msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Metabolism of lipids	0.4202537067025537	3.874398807680913	0.0001068882463872	0.1385317459220818	0.0027110746129135	183	Q8NCC3,Q9H2C2,P35790,P48651,O43772,P23786,Q06136,P48449,P53007,Q9NPH0,Q9HCL2,Q15165,Q10713,P37268,Q14914,Q14739,Q15436,Q15392,Q9UBM7,Q6IAN0,P50897,P06280,Q16850,P50416,Q9NRA0,Q9BWD1,Q96N66,Q96G23,P49748,P10619,Q16739,P16278,Q9NXE4,Q99538,Q8IV08,Q96EK7,P35610,Q9BY49,Q9C0D9,P04062,P38435,Q9UMR5,O75376,P04035	44
The canonical retinoid cycle in rods twilight vision	0.9211384524162476	3.790095281120888	0.0001505895092428	0.1894872317060799	0.0035980749275137	2	Q8TC12	1
Maturation of sars cov 1 nucleoprotein	0.9190631485324658	3.7804890134206826	0.0001565206266276	0.1961666953116125	0.0036391045690924	2	P49841	1
Protein localization	0.5154930265737436	3.670803441494885	0.0002417892319559	0.2863315372889785	0.0038769652710177	76	O60830,Q13505,P49069,O43933,P50542,P21796,Q5JRX3,Q99595,Q9NS69,O14925,Q15388,Q10713,P50402,P05067,Q13190,P12235,Q93008,Q9NR77,P09601,Q9UJ83,P46379,Q9Y512,Q8N4H5,Q9BY49	24
Transport of small molecules	0.4101577868289383	3.549725800876191	0.0003856325901254	0.4161208291936452	0.0055849608250801	155	P28072,Q13546,Q8WTV0,Q9BUN8,Q8TDW0,Q8N4V1,Q99436,Q9UBX3,Q9UBV2,P20618,P21796,P28288,Q9Y277,Q93050,Q9H2J7,P11166,P12236,P61421,P53985,O15118,Q10713,P30519,P08183,P12235,P51798,P49721,P45880,Q92530,P28074,P35612,P09601,P21281,P28070,Q9C0H2,Q9HD20,Q14997,P30825,P60900,Q9NUT2,P35610,Q9UI12,P27105,Q4KMQ2,Q70HW3,Q13555	45
Clec7a dectin 1 induces nfat activation	0.8532463682182094	3.469671175267809	0.000521095899967	0.5167002638571762	0.0070575609752822	2	O43865	1
Synthesis secretion and deacylation of ghrelin	0.8470204565668634	3.4396303416033867	0.0005825092159934	0.5564022616236495	0.0075240773732487	2	P67812	1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip	0.8470204565668634	3.4396303416033867	0.0005825092159934	0.5564022616236495	0.0075240773732487	2	P67812	1
Heme degradation	0.9027909444312144	3.310782747755555	0.0009303540838261	0.7270449225658209	0.0112855995385866	3	P30519	1
Synthesis of pe	0.8962562137759742	3.2813095789775217	0.0010332626683338	0.7635802870528254	0.0119842333266719	3	P35790	1
Vitamin d calciferol metabolism	0.8911625148279944	3.258260055960833	0.0011209762847146	0.7908365013680129	0.0128177206325977	3	P38435,Q99538	2
Downregulation of erbb4 signaling	0.8075896827749817	3.2466792364287085	0.0011675990194954	0.8040218814490532	0.0132422815625707	2	P46934	1
Metabolism of steroids	0.5708065016113024	3.1595619672130626	0.0015800649573263	0.8898523823446608	0.0154258643429614	44	P48449,Q9HCL2,Q9H2C2,P37268,Q15436,Q14739,P04062,Q15392,Q9UBM7,P38435,Q16850,Q99538,P04035	13
Transport and synthesis of paps	0.7752742365846492	3.0849631259233044	0.0020357739068606	0.9417376522885824	0.0178372554132616	2	O43252	1
Glycerophospholipid biosynthesis	0.6310775560423392	3.0536924500055913	0.002260436846396	0.9574416289512996	0.0191109660649851	29	Q9NPH0,Q8NCC3,P35790,P48651,Q9C0D9,Q8IV08	6
Sulfide oxidation to sulfate	0.7678624369997153	3.047402405106056	0.0023082846886883	0.960195657872016	0.0193979345826523	2	Q9UBX3	1
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde	0.758968277497782	3.002093728687162	0.0026812960622812	0.9763745689266072	0.0216208555311121	2	Q13555	1
Camk iv mediated phosphorylation of creb	0.758968277497782	3.002093728687162	0.0026812960622812	0.9763745689266072	0.0216208555311121	2	Q13555	1
Abc transporters in lipid homeostasis	0.7494811740290561	2.9534782031287357	0.0031421479753512	0.9876017180483472	0.0249050933273581	2	P28288	1
Ngf stimulated transcription	0.819672037415349	2.9275403311392005	0.00341654746201	0.9915555349614734	0.0267757511769887	3	P50570	1
Incretin synthesis secretion and inactivation	0.811657353626021	2.889598902175587	0.0038573364693021	0.9954443600935134	0.0292101625443781	3	P67812	1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1	0.811657353626021	2.889598902175587	0.0038573364693021	0.9954443600935134	0.0292101625443781	3	P67812	1
Hs gag degradation	0.8018979833926432	2.843155859180327	0.0044669220429436	0.9980604810995416	0.0329290797480254	3	P16278,P54802	2
Formation of xylulose 5 phosphate	0.8016287729675807	2.8418709454424644	0.0044849642667561	0.9981089014765364	0.0329290797480254	3	Q7Z4W1	1
Neurotransmitter clearance	0.7239845834568641	2.821336819364922	0.0047823961197361	0.9987535382885044	0.0345670600364351	2	P05091	1
Metabolism of fat soluble vitamins	0.8718481162859696	2.818568568702609	0.0048238306724233	0.998823870761566	0.0346868236496418	4	Q8TC12,P09455,Q6NUM9	3
Hs gag biosynthesis	0.7198339756893097	2.7996175642439645	0.0051163182068214	0.9992195069103416	0.0357690698354865	2	Q7LGA3	1
Smac xiap regulated apoptotic response	0.7121257041209735	2.759125574271556	0.0057956259693019	0.9996990052296192	0.0390574793583391	2	Q9NR28	1
P75ntr negatively regulates cell cycle via sc1	0.7112362881707743	2.754440303269394	0.0058792614328981	0.9997323349577376	0.0393850728788462	2	Q13547	1
Vitamin c ascorbate metabolism	0.7800083133078732	2.7380082992948314	0.0061812516008425	0.9998248041917552	0.0408665686406418	3	P78417	1
Antigen processing ubiquitination proteasome degradation	0.4035126868181001	2.71001169431274	0.0067280835903178	0.9999187022938292	0.0440642094295464	95	P28072,Q7Z7E8,Q96J02,Q99436,P20618,P55786,Q9UII4,P49427,P63208,Q6UWE0,Q9UJX6,P49721,P28074,Q92530,P46934,P28070,Q14997,Q14999,P60900,Q15386,Q9UIQ6,Q12834,O94822	23
Linoleic acid la metabolism	0.6990809368514663	2.6901346671341084	0.0071423190427066	0.9999545676782228	0.0463420235561665	2	O95864	1
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10	0.7680376605518429	2.679927807916965	0.007363803955481	0.9999667187235922	0.0468162991124669	3	Q7Z434	1
Rora activates gene expression	0.6967091609843004	2.6775275307058597	0.0074167757016874	0.999969106394922	0.0468162991124669	2	P50416	1
Bmal1 clock npas2 activates circadian gene expression	0.6967091609842937	2.6775275307058197	0.0074167757016883	0.999969106394922	0.0468162991124669	2	P43490	1
Cholesterol biosynthesis	0.6704908232720496	2.6407286413003073	0.0082727950661285	0.9999907283605228	0.0506164434967075	18	P48449,Q9H2C2,P37268,Q14739,Q15392,Q9UBM7,Q16850,P04035	8
Traf3 dependent irf activation pathway	0.7536336157075346	2.6094917599389875	0.0090676829861133	0.9999969705130805	0.0547997668511627	3	Q7Z434	1
Phospholipid metabolism	0.5139802344501723	2.6092395271324453	0.0090743699947086	0.9999969988981572	0.0547997668511627	43	Q9NPH0,Q8NCC3,P35790,P48651,Q9C0D9,Q8IV08	6
Activation of irf3 irf7 mediated by tbk1 ikk epsilon	0.7437722419928819	2.5609211891702945	0.0104395035097339	0.999999561390536	0.0604278315189996	3	Q9UHD2,Q6SZW1	2
Akt phosphorylates targets in the cytosol	0.8091889469946557	2.5374212434574197	0.0111672491575864	0.9999998428317696	0.0630700913960856	4	P31751,P49841	2
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects	0.8017994383994613	2.5036323486526513	0.0122925695552729	0.9999999678998016	0.0676517427240986	4	P06400	1
Mitochondrial protein import	0.5160764439560065	2.4757649042592753	0.013295109140512	0.9999999922150316	0.0713333740423625	36	O60830,O14925,Q9Y512,Q15388,Q13505,P21796,Q5JRX3,Q99595,Q9NS69,P12235	10
Ptk6 regulates proteins involved in rna processing	0.6584642751260079	2.4715137957032876	0.013454236001124	0.9999999937835214	0.0719105717301458	2	P23246	1
Innate immune system	0.3120730013187581	2.4639420235495666	0.0137418337242187	0.999999995860918	0.0728891940885368	302	P17931,P28072,P78527,O15260,P42785,Q9BRF8,P04066,Q9BUI4,P20618,Q7L576,Q93050,Q8IZP0,Q9UII4,O43865,P61421,Q969Q5,Q13464,P30519,Q9NQX7,P05067,Q07065,P06280,Q9Y2A7,P49721,Q92530,Q13685,Q6SZW1,P09601,O15126,Q7Z434,Q86UT6,P21281,P63167,P10619,P28070,P16278,Q14997,O60784,P42025,Q13576,Q9UQB8,Q99538,Q8IV08,Q9UI12,P10253,P27105,Q4KMQ2,Q14019,Q08209,Q99536,P07384,Q8NF37,P14174	53
Ra biosynthesis pathway	0.7889486999632807	2.444550236481836	0.0145032880771696	0.9999999985907904	0.0763474976137796	4	O94788	1
Transcriptional regulation by runx2	0.4567295963431561	2.437072554967019	0.0148067081206997	0.9999999990828988	0.0776517211593087	54	P28072,P28070,P31751,Q14997,P20618,P49841,P49721,P06400,Q92530	9
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.7199509512495059	2.41569468733456	0.0157052240308994	0.9999999997431815	0.080547012952591	12	P09601,P05067,Q13190,P49069,P46379	5
Carnitine metabolism	0.8282831503148802	2.3786997990395085	0.0173738186494554	0.9999999999759164	0.0871815719999651	5	O43772,P23786	2
Ub specific processing proteases	0.4077047747525437	2.3682960506929973	0.0178702299322239	0.9999999999880992	0.0884006055157888	77	P28072,P61289,Q13546,Q99436,P20618,P21796,Q9Y277,Q16186,P25787,Q96K76,Q15388,Q92890,Q93008,P49720,P49721,P28074,P45880,Q92530,P28070,Q14997,P60900,Q12834	22
Synthesis of pc	0.8237487001800796	2.358788736003959	0.0183346903529599	0.999999999993848	0.0897434843592251	5	P35790	1
Interleukin 37 signaling	0.6913688245770618	2.298020606109754	0.0215606163548383	0.9999999999999376	0.1000772732330802	3	Q9UHD2	1
Regulation by c flip	0.6792350055787543	2.2359923897990774	0.0253522696634163	0.9999999999999998	0.1140852134853733	3	Q13546	1
Caspase activation via death receptors in the presence of ligand	0.6792350055787543	2.2359923897990774	0.0253522696634163	0.9999999999999998	0.1140852134853733	3	Q13546	1
Apc c mediated degradation of cell cycle proteins	0.4238809417920939	2.216354348914824	0.0266672435700341	1.0	0.1184739005738777	57	P25787,P28072,P61289,Q12834,P63208,Q9UJX6,Q96DE5,Q99436,P28070,Q14997,P20618,P06400,O60566,P60900,P49720,P49721,P28074,Q92530	18
Rhoa gtpase cycle	0.4437356255172651	2.210502742768365	0.0270702903780888	1.0	0.1194767016558576	52	Q9BST9,Q92888,Q8NBN3,O15173,Q13464,P30519,P63167,P42166,Q14739,Q9UDY2,Q86VI3,P27105,Q13190,O75116,P49257,P28288,P11274	17
Vitamin b2 riboflavin metabolism	0.6092499258820099	2.198776808042376	0.0278937963529417	1.0	0.1206198458088342	2	Q8NFF5	1
Inflammasomes	0.7874332242501336	2.1977090929705363	0.0279698431568722	1.0	0.1206198458088342	5	P09601	1
The nlrp3 inflammasome	0.7874332242501336	2.1977090929705363	0.0279698431568722	1.0	0.1206198458088342	5	P09601	1
Purinergic signaling in leishmaniasis infection	0.7874332242501336	2.1977090929705363	0.0279698431568722	1.0	0.1206198458088342	5	P09601	1
Regulation of hmox1 expression and activity	0.4594338793698572	2.1970772171388626	0.0280149319297937	1.0	0.1206198458088342	47	P28072,P09601,P28070,P20618,P49721,Q92530	6
S phase	0.3681299412382854	2.1917287411150883	0.0283990991478773	1.0	0.1218976717270425	99	P28072,P61289,Q07864,P49005,Q99436,Q9NTI5,Q7Z5K2,P31751,P49643,P20618,P35251,P49841,P25787,O75832,P63208,P09884,Q9UJX6,P40938,P30260,Q8WVM7,P49720,P49721,P28074,Q92530,P35250,O00231,P33993,P28070,P28340,Q9Y619,O43913,Q14997,P56282,P60900,Q96DE5,O75419,Q9UBD5,P06400	38
Regulation of cholesterol biosynthesis by srebp srebf	0.5430779537198043	2.1863002103978766	0.0287936487654927	1.0	0.122460792767873	24	P48449,Q9HCL2,P37268,Q9UBM7,Q16850,P04035	6
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.7334368212200683	2.184632796417819	0.028915781245387	1.0	0.1226064280769451	4	P12235,P12236	2
Cytoprotection by hmox1	0.410637971848564	2.171902487507905	0.0298630188193047	1.0	0.1258577379242602	68	P28072,P61289,Q99436,P20618,P25787,Q9P0S2,P00403,P63208,P30519,P49720,P49721,P28074,Q92530,P09601,P28070,O75880,Q14997,O43819,P60900,P13073,O75376	21
Traf6 mediated irf7 activation	0.726535083479718	2.1517871483946753	0.031414122508568	1.0	0.1296529612409833	4	Q7Z434	1
Rac2 gtpase cycle	0.4777927592439482	2.13317047053713	0.0329107445632268	1.0	0.1350308490167689	36	Q9Y512,Q86XL3,Q13505,O15173,P42166,Q14739,Q7L576,Q9Y2A7,Q8IZP0	9
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux	0.718071559818405	2.111350940190022	0.0347421585871907	1.0	0.1404791629829887	4	O75376	1
Class i mhc mediated antigen processing presentation	0.355189773641153	2.1007766621240744	0.0356605760313333	1.0	0.1437760218604334	116	P28072,Q9UIQ6,Q9NZ08,Q12834,Q6UWE0,Q9UJX6,P28070,Q03518,O94822,Q14997,P20618,P55786,Q14999,Q9UII4,P49721,Q92530	16
Constitutive signaling by akt1 e17k in cancer	0.7573445771721248	2.062096662819388	0.0391985340207206	1.0	0.1540336759405781	5	P31751,P49841	2
Ptk6 regulates cell cycle	0.5843462792766124	2.0575027538350334	0.0396378902985836	1.0	0.154887554528079	2	P11802	1
Hedgehog off state	0.416712717861609	2.0396500611788366	0.0413851921430725	1.0	0.1612635280435369	55	P28072,P61289,Q8NCM8,Q96J02,Q99436,P20618,P10644,P49841,P25787,O75832,P63208,Q7Z4L5,P49720,P49721,P28074,Q92530,O00231,Q15008,P28070,P68371,P48729,Q14997,P60900,Q13885,P48556,P17252	26
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.4325748299506209	2.0170850299462284	0.0436866405894151	1.0	0.1669667496499566	50	P25787,P28072,P61289,Q12834,Q9UJX6,Q96DE5,Q99436,P28070,Q14997,P20618,P06400,P60900,P49720,P49721,P28074,Q92530	16
Abc family proteins mediated transport	0.4195305542094482	1.9870897529430296	0.0469124515884415	1.0	0.174803729788324	53	P25787,P28072,P61289,Q9BUN8,O75832,Q9NUT2,Q99436,P28070,Q9UBV2,Q14997,P20618,P08183,P28288,P60900,P49720,P49721,P28074,Q92530	18
Cell cycle mitotic	0.2929199826819658	1.9634184041681737	0.0495975770562928	1.0	0.1821594742811814	274	O75330,P49005,Q15005,Q8IXJ6,P49643,P49721,P28074,Q92530,P35250,Q12769,Q92674,Q13547,P42695,P60900,Q99640,Q96DE5,Q6KC79,Q15021,P28072,Q86XI2,P00374,Q8NBT2,Q92621,Q96EE3,Q99436,Q9HBM1,P31751,P20618,P49841,Q86XL3,P63208,P50748,Q14739,Q9BZD4,Q9Y570,P49720,Q16537,Q96CW5,Q6IBW4,P63167,P28070,Q9P258,O43913,Q14997,Q12834,Q9BTX1,Q9UBD5,P06400,Q9H6D7,Q07864,P61289,Q5SRE5,O95684,P21127,Q15003,Q00534,Q9BPX3,Q9NQS7,P25787,O75832,P09884,Q9UJX6,Q96BD8,Q8TD19,P30153,Q8WVM7,Q96SN8,Q9BS16,P41208,P42166,P04183,Q7Z5K2,P35251,P50402,P04818,O75935,O60566,Q9Y6X3,Q9Y619,Q15154	80
Deubiquitination	0.3538451194400767	1.9632209854298923	0.0496205019547304	1.0	0.1821594742811814	96	P28072,Q13546,Q99436,P20618,P21796,Q9Y277,Q16186,Q96K76,Q15388,Q92890,Q93008,P49721,P28074,P45880,Q92530,Q7Z434,P28070,Q14997,P60900,O95630,Q12834,Q96RL1	22
Antigen processing cross presentation	0.4235940576894501	1.9561251230186465	0.0504504163030625	1.0	0.1837554327487527	51	P28072,Q9UIQ6,P28070,Q03518,P20618,P49721,Q92530	7
Cyclin a cdk2 associated events at s phase entry	0.4419870577802969	1.9408051725362587	0.0522819133860883	1.0	0.1889462931958374	44	P25787,P28072,P61289,P63208,Q99436,P28070,P31751,P20618,P06400,P60900,P49720,P49721,P28074,Q92530	14
Activation of gene expression by srebf srebp	0.5578556983753284	1.9154621155381408	0.05543359609918	1.0	0.1977745947784046	18	P48449,Q9HCL2,Q9UBM7,Q16850,P04035	5
Role of phospholipids in phagocytosis	0.6143048044342236	1.896850847769703	0.0578476261671161	1.0	0.2024161197417861	3	Q8IV08	1
Gamma carboxylation hypusine formation and arylsulfatase activation	0.7002710911157717	1.8942972517887169	0.0581855656031944	1.0	0.2024161197417861	9	P38435,O60725,Q9HA64,P49366	4
Heme signaling	0.7191352503859293	1.8871712916116712	0.059137290300935	1.0	0.2044461609266478	5	P09601	1
Alpha oxidation of phytanate	0.6716736930787074	1.8866634890617875	0.0592056014333763	1.0	0.2044461609266478	4	Q9BY49	1
Glycogen storage diseases	0.6716688682136857	1.8866398676124587	0.0592087806554593	1.0	0.2044461609266478	4	P10253,Q04446	2
Free fatty acids regulate insulin secretion	0.5532167210198726	1.877933959911004	0.0603901999488327	1.0	0.2064811983544649	2	O95573	1
Regulation of runx2 expression and activity	0.4328520686474564	1.8733803430333484	0.0610158824540756	1.0	0.2070977032200377	45	P28072,P28070,P20618,P49841,P49721,Q92530	6
Myoclonic epilepsy of lafora	0.5505484731692947	1.8623946418764248	0.0625474838522412	1.0	0.2106420832895809	2	P13807	1
Small interfering rna sirna biogenesis	0.6665867611596326	1.8617306067274104	0.0626410721327694	1.0	0.2106420832895809	4	Q15631	1
Metabolism of porphyrins	0.7172081686642493	1.860497794411891	0.0628151302139539	1.0	0.2106420832895809	8	P30519	1
Switching of origins to a post replicative state	0.3918436114887511	1.858687255572845	0.0630714809538954	1.0	0.2109945226155496	60	P25787,P28072,P61289,P63208,Q9UJX6,Q96DE5,Q99436,Q9Y619,P28070,O43913,Q14997,P20618,Q9UBD5,P60900,P49720,P49721,P28074,Q92530	18
Degradation of beta catenin by the destruction complex	0.4173484209578137	1.854934446338788	0.0636055882689041	1.0	0.2122722383615342	50	P25787,P28072,P61289,P49720,O75832,P63208,Q13547,Q99436,P28070,Q16537,P30153,Q14997,P20618,P60900,P49841,P49721,P28074,Q92530	18
G1 s specific transcription	0.667208878748119	1.8536408008757543	0.0637905662827762	1.0	0.2123814796288134	10	P00374,P09884,Q13547,P04818,Q9Y619,P04183	6
Signaling by the b cell receptor bcr	0.4245927412326929	1.8410010135144403	0.0656214101793506	1.0	0.2165504793087637	47	P25787,P28072,P61289,O43865,P63208,Q99436,P28070,Q08209,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	16
Class a 1 rhodopsin like receptors	0.7356175565043006	1.8409185568643096	0.0656334945735546	1.0	0.2165504793087637	7	P42892,P05067	2
Peptide ligand binding receptors	0.7356175565043006	1.8409185568643096	0.0656334945735546	1.0	0.2165504793087637	7	P42892,P05067	2
Nicotinamide salvaging	0.6037672261280935	1.84071255068699	0.0656636937258832	1.0	0.2165504793087637	3	Q9BQG2	1
Iron uptake and transport	0.5451678186183505	1.8306825605235744	0.0671479375661934	1.0	0.2198858518892953	18	P09601,P61421,Q9UI12,P30519,Q93050	5
Cdt1 association with the cdc6 orc origin complex	0.4350739284629702	1.8294158962999096	0.067337328032567	1.0	0.2199896313944522	42	P25787,P28072,P61289,Q99436,Q9Y619,P28070,O43913,Q14997,P20618,Q9UBD5,P60900,P49720,P49721,P28074,Q92530	15
Ion channel transport	0.4750832234825364	1.8250330593688948	0.0679960406614534	1.0	0.2216226091652514	29	P61421,Q9UI12,P21281,P27105,Q9C0H2,Q9HD20,Q4KMQ2,P51798,Q93050	9
Adenylate cyclase inhibitory pathway	0.6005338078291678	1.823429052880795	0.0682384333902919	1.0	0.2218942064789212	3	P08754,P63096	2
Prolactin receptor signaling	0.5987713062047719	1.8139968127453985	0.0696782164632872	1.0	0.2260490975960131	3	P63208	1
Ddx58 ifih1 mediated induction of interferon alpha beta	0.5548225859665257	1.809977890143872	0.0702992159399573	1.0	0.2275345852348967	17	Q13546,Q7Z434,Q86UT6,Q96J02,P05067,Q9UHD2,Q9UII4	7
Phase i functionalization of compounds	0.5997041292138654	1.805654680920374	0.0709722956980205	1.0	0.2278504677847859	13	P07099,P30837	2
Degradation of gli1 by the proteasome	0.4305646963719921	1.8051568191957923	0.0710501458683741	1.0	0.2278504677847859	43	P25787,P28072,P61289,P63208,Q96J02,Q99436,P28070,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	14
Degradation of axin	0.4387454463822455	1.798459647269626	0.0721041978082783	1.0	0.2289075886029333	38	P28072,P28070,P20618,P49721,Q92530	5
Cross presentation of soluble exogenous antigens endosomes	0.4387454463822455	1.798459647269626	0.0721041978082783	1.0	0.2289075886029333	38	P28072,P28070,P20618,P49721,Q92530	5
Orc1 removal from chromatin	0.4057382436879316	1.7973704907719132	0.0722768222331964	1.0	0.2289075886029333	52	P25787,P28072,P61289,P63208,Q99436,Q9Y619,P28070,O43913,Q14997,P20618,Q9UBD5,P60900,P49720,P49721,P28074,Q92530	16
Asymmetric localization of pcp proteins	0.436919014168672	1.7954565457650769	0.0725809901973575	1.0	0.2289075886029333	39	P28072,P28070,P20618,P49721,Q92530	5
Degradation of dvl	0.436919014168672	1.7954565457650769	0.0725809901973575	1.0	0.2289075886029333	39	P28072,P28070,P20618,P49721,Q92530	5
Separation of sister chromatids	0.3389628345273409	1.7904711436009058	0.0733782021812694	1.0	0.2295125382127149	111	P28072,P61289,Q15005,Q8NBT2,Q96EE3,Q99436,Q9NTI5,Q9HBM1,Q7Z5K2,P20618,Q9NQS7,O14777,P25787,O75832,P50748,Q9UJX6,P30260,Q96BD8,Q9BZD4,P30153,Q8WVM7,Q9BS16,O60566,P49720,P49721,P28074,Q16537,Q92530,O00231,Q12769,Q92674,P63167,P28070,Q9P258,Q02224,Q8WUM0,Q14204,Q14997,P60900,Q13885,Q12834,Q96DE5	42
Cytosolic sulfonation of small molecules	0.6516118426098987	1.7880100345908607	0.0737743888970114	1.0	0.2302355089738949	4	O43252,Q9NX62	2
Regulation of ras by gaps	0.4319509452583939	1.7633487399613903	0.0778416895807345	1.0	0.2401642277376197	40	P28072,P28070,P20618,P49721,Q92530	5
Caspase activation via extrinsic apoptotic signalling pathway	0.6920521140122312	1.7614576524563066	0.0781609744751823	1.0	0.2401642277376197	5	Q13546,Q9UKG1,P49327	3
Tnfr2 non canonical nf kb pathway	0.4256743746666513	1.756589677367688	0.0789877737287014	1.0	0.2421713062671177	43	P25787,P28072,P61289,P63208,Q99436,P28070,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	13
Dectin 1 mediated noncanonical nf kb signaling	0.4274348472881076	1.7543553863765085	0.079369630808556	1.0	0.2421783152727814	42	P25787,P28072,P61289,P63208,Q99436,P28070,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	13
Synthesis of dna	0.3440667026985248	1.7411660806228637	0.0816544709916406	1.0	0.2456769044378113	87	P28072,P61289,Q07864,P49005,Q99436,P49643,P20618,P35251,P25787,O75832,P63208,P09884,Q9UJX6,P40938,P30260,P49720,P49721,P28074,Q92530,P35250,O00231,P33993,P49642,P28070,P28340,Q9Y619,O43913,Q14997,P56282,P60900,P48556,Q96DE5,O75419,Q9UBD5	34
Signaling by hedgehog	0.3816789411708034	1.736839309865338	0.0824155382979439	1.0	0.2467749995023116	60	P28072,P61289,Q8NCM8,Q96J02,Q99436,Q9UBV2,P20618,P10644,P49841,P25787,O75832,P63208,Q7Z4L5,P49720,P49721,P28074,Q92530,O00231,Q15008,P28070,P68371,P48729,Q14997,P60900,Q13885,P48556,P17252	27
Sphingolipid metabolism	0.4663184364523858	1.7349263321772046	0.0827538544015693	1.0	0.2467919567934015	28	Q96G23,P10619,Q16739,P16278,P04062,P06280,Q06136,Q9NRA0	8
Signaling by vegf	0.4492198944522149	1.721674668755966	0.0851284685534023	1.0	0.2515979102372804	32	Q13685,O43865,Q13464,P31751,Q9UQB8,Q9Y2A7	6
Traf6 mediated nf kb activation	0.7274293814683415	1.71026759514398	0.0872164011381591	1.0	0.2566811805648353	6	P05067	1
Glycogen metabolism	0.6157365247024869	1.7043151951564988	0.0883222176841389	1.0	0.2582311546349052	11	P10253,P06737,Q04446,P46020	4
Regulation of pten stability and activity	0.4160133258896126	1.6806455505689846	0.0928317825717477	1.0	0.2664252644623993	44	P28072,P28070,P31751,P20618,P49721,Q92530	6
Stabilization of p53	0.4248335562872386	1.6797287147508844	0.0930101102460132	1.0	0.2664252644623993	39	P28072,P28070,P20618,P49721,Q92530	5
Cellular response to hypoxia	0.4194386775299368	1.6754784716949174	0.0938403915426013	1.0	0.2671578493916917	42	P28072,P28070,P20618,P49721,Q92530	5
Synthesis of pa	0.6777828649240036	1.6726279349784037	0.0944005640419896	1.0	0.268205268510337	8	Q9NPH0,Q9HCL2	2
Downstream signaling events of b cell receptor bcr	0.4149409940727487	1.669831451387298	0.0949527158011478	1.0	0.2686795913643027	44	P25787,P28072,P61289,P63208,Q99436,P28070,Q08209,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	15
Glycosaminoglycan metabolism	0.555251405028606	1.6650809883906683	0.0958965991280083	1.0	0.2697091850475233	15	Q7LGA3,O75330,Q9UHD1,P54802,P16278,O43252,Q8NCH0,P06865,P08236	9
Sphingolipid de novo biosynthesis	0.5841979219660501	1.659463268277748	0.0970224764339156	1.0	0.2712351796098442	12	Q9NRA0,Q96G23	2
Hedgehog on state	0.41556344636258	1.6558083141697353	0.0977606435386593	1.0	0.27185562997919	43	P25787,P28072,P61289,O75832,Q96J02,Q99436,P28070,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	14
Wax and plasmalogen biosynthesis	0.6249171801603915	1.655470719677674	0.0978290510749486	1.0	0.27185562997919	4	O00116,Q6IAN0	2
Heparan sulfate heparin hs gag metabolism	0.7145010284440075	1.6528907223847578	0.0983531056494255	1.0	0.2724089446012002	6	Q7LGA3,P16278,P54802,P08236	4
Rac3 gtpase cycle	0.4255030502346595	1.6411035719681264	0.1007759174107352	1.0	0.2766850065500744	35	Q9UQB8,O15173,P50402,P42166,Q14739,Q7L576,Q9Y2A7,Q8IZP0,P11274	9
Rhoc gtpase cycle	0.4244303819454433	1.6402397961901474	0.1009553178021418	1.0	0.2766850065500744	36	Q9BST9,Q92888,Q86VI3,Q13464,P63167,P42166,P27105,Q14739,Q9UDY2,Q13190,O75116,P49257,P28288,P11274	14
Synthesis of diphthamide eef2	0.5111176993774207	1.6302754965127562	0.1030432839576735	1.0	0.2796442811126423	2	P13639	1
G1 s dna damage checkpoints	0.4165917541133899	1.6301705800867818	0.1030654499483103	1.0	0.2796442811126423	41	P28072,P28070,P20618,P49721,Q92530	5
Map3k8 tpl2 dependent mapk1 3 activation	0.6174970220338293	1.6183952257010428	0.1055774502633424	1.0	0.2843253728134415	4	P63208	1
Mitotic g2 g2 m phases	0.3311271665868573	1.6112176823871394	0.1071322850971545	1.0	0.2874029571356357	97	P28072,O75330,Q9H6D7,P61289,O95684,Q99436,P21127,P20618,P07437,P25787,Q99996,P61163,O75832,P63208,O75935,P30153,Q9Y570,Q96SN8,Q9BSJ2,P49720,P49721,O94927,P28074,Q92530,P41208,O00231,Q96CW5,Q15008,P63167,P68371,P63151,P28070,Q14204,Q14997,Q9BVA1,Q15154,P60900,Q99640,Q13885,P48556,P30307,O14980,O95067,P17252	44
G alpha i signalling events	0.4669148282919617	1.603626101231575	0.108796493825197	1.0	0.2907492507397508	24	O43865,P63096,P05067,P52292,Q08209,P30153,Q9NZJ7,Q00535,Q13555	9
Slc mediated transmembrane transport	0.4812281002682756	1.5979412172076397	0.1100560599499269	1.0	0.2926619446746552	21	P11166,P12236,P53985,P05141,Q9UBX3,Q70HW3,P30825,Q8TB61,P12235,Q9H2J7	10
Tcf dependent signaling in response to wnt	0.3690655647879884	1.5960444027629104	0.1104788801425957	1.0	0.2926619446746552	62	P28072,P61289,Q99436,P31751,P20618,Q9UBL3,P49841,P25787,O75832,P30153,P49720,P49721,P28074,Q16537,Q92530,Q13547,P28070,Q14997,P60900	19
Gap junction assembly	0.6129592398884283	1.595675868177825	0.1105611790993141	1.0	0.2926619446746552	4	Q13885,P68371	2
Transport of connexons to the plasma membrane	0.6129592398884283	1.595675868177825	0.1105611790993141	1.0	0.2926619446746552	4	Q13885,P68371	2
Clec7a dectin 1 signaling	0.3918730310416881	1.580622470317096	0.113964384883088	1.0	0.2993979602860787	50	P25787,P28072,P61289,O43865,P49427,P63208,Q99436,P28070,Q08209,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	17
Auf1 hnrnp d0 binds and destabilizes mrna	0.4095295971100832	1.5773620540427786	0.1147122414352883	1.0	0.3002318514113081	42	P25787,P28072,P61289,Q14103,Q99436,P28070,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	13
Amino acid transport across the plasma membrane	0.6089935190527428	1.5757933890379543	0.1150734264614465	1.0	0.3006131646324306	4	P30825	1
Post chaperonin tubulin folding pathway	0.6328773986741418	1.5583506125601605	0.119150157212986	1.0	0.3101016218509618	9	Q13885,Q99426,P68371,Q9BTW9,Q15813	5
Defective cftr causes cystic fibrosis	0.405544763663118	1.5555380473176703	0.1198179804591994	1.0	0.3106804511906751	43	P25787,P28072,P61289,Q9BUN8,Q99436,P28070,Q9UBV2,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	14
Interleukin 1 family signaling	0.3866292100367852	1.5539357887656675	0.1201997338646374	1.0	0.3110920755865848	51	P25787,P28072,P61289,P63208,P05067,Q99436,P28070,Q9UHD2,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	16
Gpcr ligand binding	0.6095105791190675	1.5522635363564934	0.1205991789413332	1.0	0.3115128371341918	10	P42892,P05067	2
Uch proteinases	0.3990379832260458	1.5513871990231944	0.120808921067812	1.0	0.3115128371341918	46	P25787,P28072,P61289,Q99436,P28070,P49721,Q14997,P20618,P60900,P49720,Q16186,P28074,Q92530	13
C type lectin receptors clrs	0.3734551177438637	1.5444409669396628	0.1224815419991389	1.0	0.3145359766290604	55	P25787,P28072,P61289,O43865,P49427,Q16512,P63208,Q99436,P28070,Q08209,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	18
Synthesis of pyrophosphates in the cytosol	0.4965905721909406	1.5437134883902996	0.1226577571944149	1.0	0.3145359766290604	2	Q9BW91	1
Galactose catabolism	0.4945152683071568	1.5313086578982198	0.1256931267900904	1.0	0.3205519412654044	2	Q96G03	1
Abc transporter disorders	0.4004885779758075	1.523665249807524	0.1275923544039332	1.0	0.3228241637145715	44	P25787,P28072,P61289,Q9BUN8,Q99436,P28070,Q9UBV2,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	14
Hedgehog ligand biogenesis	0.4053472326949904	1.519703376921979	0.1285855425081141	1.0	0.3237848949437171	41	P25787,P28072,P61289,Q99436,P28070,Q9UBV2,Q14997,P20618,P60900,P49720,P49721,P28074,Q92530	13
Interleukin 1 signaling	0.3911867562862398	1.51786844721924	0.129047565639583	1.0	0.3243628001211142	48	P28072,P05067,P28070,P20618,P49721,Q92530	6
Stimuli sensing channels	0.599714273006149	1.500532462703632	0.1334765310318251	1.0	0.3321091198383311	10	Q13546,P27105,Q9C0H2,Q4KMQ2,P51798	5
Signaling by insulin receptor	0.5185170339934897	1.5002183128087554	0.1335578610962751	1.0	0.3321091198383311	16	Q9UI12,P31751,Q93050,P61421	4
Mitotic g1 phase and g1 s transition	0.3358330663397031	1.4934830998860882	0.1353107748357198	1.0	0.3346782462692007	80	P28072,P61289,Q07864,P00374,Q99436,Q00534,P31751,P49643,P20618,P25787,O75832,P63208,P09884,P04818,P49720,P49721,P28074,Q92530,Q13547,P28070,P04183,Q9Y619,O43913,P60900,Q9UBD5,P06400	26
Regulation of runx1 expression and activity	0.5923104130217923	1.4918955103771312	0.1357265398404923	1.0	0.3351124302256403	4	Q00534	1
Scf skp2 mediated degradation of p27 p21	0.4002687188305623	1.4853794340468962	0.1374433404394976	1.0	0.3385255747822756	42	P25787,P28072,P61289,P63208,Q99436,P28070,P20618,P60900,P49720,P49721,P28074,Q92530	12
Suppression of apoptosis	0.5909048137245647	1.4848096085641564	0.1375942658792475	1.0	0.3385255747822756	4	P49840	1
Biological oxidations	0.3987498118970243	1.4547322312395023	0.1457434059113067	1.0	0.3535490423635257	41	P78417,Q99707,P48507,P07099,P30837,Q8WUX2,O43252,Q16850,Q9NX62,O00170,Q9UI30,Q9NUJ1	12
Mitotic metaphase and anaphase	0.2980712632106836	1.4538729265755226	0.1459815400726816	1.0	0.3535490423635257	145	P28072,P61289,Q15005,Q8NBT2,Q92621,Q96EE3,Q5SRE5,Q99436,Q9NTI5,Q8IXJ6,Q9HBM1,Q7Z5K2,P20618,Q9NQS7,O14777,P25787,Q86XL3,O75832,P50748,Q9UJX6,P50402,P30260,Q96BD8,Q14739,Q86Y07,Q9BZD4,P30153,Q8WVM7,Q9BS16,O60566,P49720,P49721,P28074,Q92530,Q16537,O00231,Q12769,Q92674,P63167,P42166,P28070,Q9P258,Q02224,Q8WUM0,Q14204,Q14997,P60900,Q13885,Q12834,Q9BTX1,Q96DE5,O95067	52
Interleukin 9 signaling	0.479988141120674	1.4442391308621538	0.148671721176651	1.0	0.3588184274073153	2	P42224	1
Interleukin 21 signaling	0.479988141120674	1.4442391308621538	0.148671721176651	1.0	0.3588184274073153	2	P42224	1
Mucopolysaccharidoses	0.5817633878987477	1.4386687136102647	0.1502444076672944	1.0	0.3614733371514725	4	P16278,P54802	2
Circadian clock	0.5878621595737521	1.4377876540825083	0.1504943133855012	1.0	0.3614733371514725	10	Q9BWF3,Q96EB6,P43490,P63208,P50416,O75376	6
Visual phototransduction	0.6291444706612683	1.4375946129376072	0.1505491103118319	1.0	0.3614733371514725	8	Q8TC12,P50579,Q6NUM9	3
Negative regulators of ddx58 ifih1 signaling	0.6269951634799326	1.4271472927387052	0.1535374431781284	1.0	0.3673837619785406	8	Q86UT6,Q96J02,Q9UII4,Q7Z434	4
Dna damage reversal	0.5791530449765843	1.425476344432102	0.1540195533490371	1.0	0.3679062960991555	4	Q8N3C0,Q6P6C2	2
Wnt mediated activation of dvl	0.4755410613697102	1.4175124952357303	0.1563331437455095	1.0	0.3727944197008304	2	P19784	1
Oncogene induced senescence	0.6412009925811861	1.4045071408702072	0.1601678867697413	1.0	0.3812870342044184	7	Q00534,P06400	2
Mapk6 mapk4 signaling	0.3755401031724989	1.4035308391640435	0.1604586024330827	1.0	0.3813146824461982	50	P25787,P28072,P61289,Q16512,Q99436,P28070,Q92530,Q14997,P20618,P60900,P49720,P49721,P28074,Q9HCE1	14
Regulation of mecp2 expression and activity	0.5610074461989906	1.402633392984027	0.1607261887300104	1.0	0.3813146824461982	11	P42858,Q14739,O75376,Q13555,Q9HCE1	5
Condensation of prophase chromosomes	0.5380378696111103	1.392201463767378	0.1638613996563358	1.0	0.3861261022307238	12	Q6IBW4,P42695,Q86XI2	3
Glycogen breakdown glycogenolysis	0.6367245121919737	1.3835663339212363	0.1664912828058256	1.0	0.389400293172471	7	P10253	1
Diseases of metabolism	0.38440355793246	1.3792523902770075	0.1678169500633135	1.0	0.389400293172471	45	Q99707,P48507,P54802,P10253,P08236,P10619,Q9BT22,Q06210,P16278,Q7Z4W1,Q9Y223,Q8NCH0,Q2TAA5,P06865,Q04446	15
Regulation of runx3 expression and activity	0.3947791180593271	1.3787801136328934	0.167962559896406	1.0	0.389400293172471	38	P28072,P49721,P20618,Q92530	4
Neddylation	0.3256162804739819	1.348477782333687	0.1775047614010863	1.0	0.4089776128478248	80	P28072,P61289,Q99436,P20618,P25787,O75832,P63208,Q86VX2,P49720,P49721,P28074,Q92530,Q16531,Q9BTE7,P28070,Q14997,Q14999,P60900,Q9NV06,P61201,Q7L5N1,Q5TAQ9	22
Sialic acid metabolism	0.6041230720957944	1.345545962531582	0.178448988821787	1.0	0.4095151814678345	5	P16278,P10619	2
Metabolism of polyamines	0.3884453986737185	1.3400134965089423	0.1802409571170697	1.0	0.4115157695226061	40	P28072,P28070,P20618,P49721,Q92530	5
Interleukin 6 family signaling	0.510993091648001	1.336009590605013	0.1815461385896402	1.0	0.4117997777765009	3	Q06124	1
Interleukin 6 signaling	0.510993091648001	1.336009590605013	0.1815461385896402	1.0	0.4117997777765009	3	Q06124	1
Interleukin 20 family signaling	0.510993091648001	1.336009590605013	0.1815461385896402	1.0	0.4117997777765009	3	Q06124	1
Cyclin a b1 b2 associated events during g2 m transition	0.525325097382225	1.318153884870122	0.1874521392509764	1.0	0.4224486821568856	12	P30307,P63151,O14980,P30153,Q9Y570,O95067,P53350,Q99640	8
Diseases of carbohydrate metabolism	0.5644479633596065	1.3134772423279766	0.1890221845347111	1.0	0.4252999152030999	10	P54802,P10253,P16278,Q7Z4W1,P08236	5
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway	0.4574562703824555	1.3085692803245124	0.190680292476105	1.0	0.4283397874463229	2	P18887	1
Transport of inorganic cations anions and amino acids oligopeptides	0.5605102667173686	1.2925447308506886	0.1961685656805962	1.0	0.4385499184686406	10	Q9UBX3,P30825	2
Ctla4 inhibitory signaling	0.6317028994565008	1.2811230702185064	0.2001504417282564	1.0	0.4467357859374684	6	P31751,P30153,Q16537	3
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components	0.4524162466646962	1.2781589716289057	0.2011933792572624	1.0	0.4476312026537178	2	P12814	1
M phase	0.282770674666946	1.256577932193527	0.2089065097854141	1.0	0.4605007241845479	210	P28072,Q9H6D7,Q86XI2,P61289,Q15005,Q8NBT2,Q92621,Q96EE3,Q5SRE5,O95684,Q99436,Q15003,Q8IXJ6,Q9HBM1,Q7Z5K2,Q9BPX3,P20618,Q9NQS7,P25787,Q86XL3,O75832,P50748,Q9UJX6,P50402,O75935,Q96BD8,Q14739,Q8TD19,Q9BZD4,P30153,Q8WVM7,Q96SN8,Q9BS16,O60566,P49720,P49721,P28074,Q92530,Q16537,P41208,Q9Y6X3,Q12769,Q96CW5,Q92674,Q6IBW4,P63167,P42166,P28070,Q9P258,P42695,Q14997,Q15154,P60900,Q12834,Q9BTX1,Q96DE5,Q6KC79,Q15021,P06400	59
Diseases associated with n glycosylation of proteins	0.5847930404632024	1.2531693056120994	0.2101440979709865	1.0	0.4619722593977327	5	O75340,Q9BT22,Q2TAA5	3
Negative regulation of notch4 signaling	0.3781485043944287	1.2516203485751132	0.210708236255519	1.0	0.4619722593977327	41	P25787,P28072,P61289,P63208,Q99436,P28070,P20618,P60900,P49720,P49721,P28074,Q92530	12
Rnd3 gtpase cycle	0.480011500199082	1.2515454422883376	0.2107355452631605	1.0	0.4619722593977327	16	O43396,Q13464,Q9NNW5,Q07065,P12277,O75976	6
Cellular response to chemical stress	0.3232373080135713	1.2509553347300086	0.2109507736461331	1.0	0.4619722593977327	78	P28072,P61289,Q99436,P20618,P25787,Q9P0S2,P00390,P00403,P63208,P30519,P49720,P49721,P28074,Q92530,P09601,P28070,O75880,Q14997,O43819,P60900,P13073,O75376	22
Irf3 mediated induction of type i ifn	0.6226627188838505	1.2402923472187628	0.2148672819483343	1.0	0.4667377501125141	6	P78527,Q9UJV9	2
Sting mediated induction of host immune responses	0.6226627188838505	1.2402923472187628	0.2148672819483343	1.0	0.4667377501125141	6	P78527,Q9UJV9	2
Cdc6 association with the orc origin complex	0.5425026766562493	1.2397438741548996	0.2150701436281261	1.0	0.4667377501125141	4	O43913,Q9UBD5	2
Beta catenin independent wnt signaling	0.3408650797123366	1.238789864132723	0.2154233285077049	1.0	0.4667377501125141	57	P25787,P28072,P61289,O75832,Q99436,P07737,P28070,Q08209,Q92530,Q14997,P20618,P60900,P49720,P49721,P28074,Q9HCE1	16
Insulin receptor recycling	0.5503762041762299	1.2386668587602785	0.2154688968261355	1.0	0.4667377501125141	10	Q9UI12,Q93050,P61421	3
Pink1 prkn mediated mitophagy	0.5498969661945952	1.2361192236384175	0.2164142502267099	1.0	0.467334178121146	10	P21796,Q9NS69,Q15388	3
Fceri mediated nf kb activation	0.3676205477154927	1.2258072965123217	0.2202712007647589	1.0	0.4720097159244834	46	P25787,P28072,P61289,P49427,P63208,Q99436,P28070,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	15
Adaptive immune system	0.2851504683913493	1.2236363714181888	0.2210894325287906	1.0	0.4730364392295444	195	P50570,P28072,Q7Z7E8,Q96J02,Q99436,P31751,P20618,P55786,Q9UII4,O43865,P49427,P63208,Q6UWE0,Q9UJX6,O75935,Q15436,P49720,P49721,P28074,Q92530,Q9NZ08,P46934,P63167,P10619,P28070,Q9NZ32,Q14997,P42025,Q14999,Q5KU26,P60900,Q99538,Q15386,Q9UIQ6,Q12834,Q03518,Q08209,O94822,P78310	39
Signaling by ctnnb1 phospho site mutants	0.6017561671906451	1.219720201477652	0.2225709607907982	1.0	0.4740251760353641	7	P30153,P49841,Q16537	3
Disassembly of the destruction complex and recruitment of axin to the membrane	0.6017561671906451	1.219720201477652	0.2225709607907982	1.0	0.4740251760353641	7	P30153,P49841,Q16537	3
Beta catenin phosphorylation cascade	0.6017561671906451	1.219720201477652	0.2225709607907982	1.0	0.4740251760353641	7	P30153,P49841,Q16537	3
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.5271869108209151	1.2147205913340315	0.2244726762277165	1.0	0.4756407570668404	11	P05067,P09601	2
Pcp ce pathway	0.355674243234199	1.214142336577441	0.2246933755606077	1.0	0.4756407570668404	51	P28072,P28070,P20618,P49721,Q92530	5
Ros and rns production in phagocytes	0.5647176898079935	1.212656105329767	0.2252613285708427	1.0	0.476120535388372	9	Q9UI12,Q93050,P61421	3
Transferrin endocytosis and recycling	0.5264463355709361	1.2106056748826413	0.2260465682906502	1.0	0.4770574323229306	11	Q9UI12,Q93050,P61421	3
Sulfur amino acid metabolism	0.5258398961477055	1.207236267777674	0.2273411669141145	1.0	0.4790648456875978	11	Q9UBX3,Q13126	2
Mitophagy	0.4983090833900859	1.204630496795677	0.2283459781595831	1.0	0.4802266777328744	13	P21796,Q9NS69	2
Mitotic prometaphase	0.3040490065936248	1.1915978296209109	0.2334189764433736	1.0	0.4896533415616634	103	Q9H6D7,P17252,Q15005,Q8NBT2,O95684,Q96EE3,Q15003,Q9HBM1,Q9NTI5,Q7Z5K2,O43684,Q9BPX3,Q9NQS7,P07437,O14777,Q99996,P61163,P50748,O75935,Q96BD8,Q8TD19,Q9BZD4,P30153,Q8WVM7,Q96SN8,Q9BS16,Q9BSJ2,O60566,O94927,Q16537,P41208,Q12769,Q96CW5,Q92674,P63167,P68371,Q9P258,Q02224,Q8WUM0,Q14204,Q9BVA1,Q15154,Q13885,Q12834,O14980,Q15021,O95067,O60216,P43034	49
Rhob gtpase cycle	0.4026406180509762	1.1875756544043357	0.2350006341425481	1.0	0.4908652472996596	27	Q9BST9,Q92888,Q86VI3,Q13464,P63167,P27105,Q9UDY2,O75116,P11274	9
The role of gtse1 in g2 m progression after g2 checkpoint	0.353235236449017	1.1874445427914826	0.2350523191370412	1.0	0.4908652472996596	51	P28072,P28070,P20618,P49721,Q92530	5
Retrograde transport at the trans golgi network	0.4256298582147433	1.184702937749733	0.236134920534945	1.0	0.4922085022701798	21	P20645,Q5VZE5,Q96MW5,O60499	4
Fc epsilon receptor fceri signaling	0.3390112371924542	1.180426877800442	0.2378304771669519	1.0	0.4935964295540242	56	P25787,P28072,P61289,O43865,P49427,Q16512,P63208,Q99436,P28070,Q08209,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	18
Deactivation of the beta catenin transactivating complex	0.5561531472101596	1.1691384899049593	0.2423478385830151	1.0	0.500994628616161	9	P31751,Q9UBL3	2
Diseases of glycosylation	0.4368922946484694	1.1628844739316029	0.2448763775651432	1.0	0.5028981491924923	19	Q9BT22,P10619,Q06210,P16278,Q9Y223,Q2TAA5,P06865,Q8NCH0	8
Regulation of innate immune responses to cytosolic dna	0.4794232282612997	1.1619109783254162	0.2452716272725243	1.0	0.5028981491924923	3	Q9UJV9	1
Keratinization	0.5653938059346586	1.160460621755245	0.2458613173829962	1.0	0.5028981491924923	5	P07384	1
Formation of the cornified envelope	0.5653938059346586	1.160460621755245	0.2458613173829962	1.0	0.5028981491924923	5	P07384	1
Glycosphingolipid metabolism	0.4640783766850681	1.1486132756994245	0.2507154804083975	1.0	0.5113276245171265	16	P10619,Q16739,P04062,P16278,Q9NXE4,P06280,O43681,P06865	8
Regulation of tnfr1 signaling	0.599580962509682	1.1361156115566324	0.2559081821549331	1.0	0.5203963762480055	6	Q96EP0,Q96BN8	2
Cytosolic trna aminoacylation	0.4105447894420426	1.1286361132810787	0.2590513698444252	1.0	0.5244944280594677	23	P49589,Q13155,Q9NSD9,Q9P2J5,P41252,P07814,P26640,O43324,O43776	9
Opioid signalling	0.4314132280892823	1.124173885265695	0.2609392657953657	1.0	0.5275511243254134	19	O43865,P63096,P52292,Q08209,P30153,Q00535,Q13555	7
Methylation	0.5791489314238264	1.113877699905902	0.2653316574395605	1.0	0.5319359553671719	7	P78417,Q99707,Q9UI30	3
Regulation of ifng signaling	0.4703784275743284	1.1120964593112668	0.2660966789281009	1.0	0.5319359553671719	3	Q06124	1
Regulation of ifna signaling	0.4703784275743284	1.1120964593112668	0.2660966789281009	1.0	0.5319359553671719	3	Q06124	1
Mapk family signaling cascades	0.299916207433341	1.1119523563681584	0.2661586357321046	1.0	0.5319359553671719	92	P28072,P28070,Q9Y4G8,O60725,Q14997,P20618,P49721,Q92530	8
Signaling by notch4	0.3594289755846626	1.1073850201155526	0.2681274996947369	1.0	0.535062693451301	44	P25787,Q06330,P28072,P61289,P63208,Q99436,P28070,P20618,P60900,P49720,P49721,P28074,Q92530	13
Branched chain amino acid catabolism	0.4660198189585681	1.105829775792889	0.2688002045188939	1.0	0.535062693451301	15	Q02252	1
Metabolism of carbohydrates	0.2987130329344111	1.1048535593450015	0.2692230483373388	1.0	0.535062693451301	100	O75330,Q00796,Q92621,Q96EE3,Q5SRE5,Q9UBX3,P52789,P46020,P19367,P08236,P11166,Q7LGA3,P53007,P09972,P30153,Q93063,O43252,P06865,Q04446,Q12769,Q8WUM0,P08237,P16278,P78406,Q9BRR6,Q9BTX1,Q9UHD1,P10253,P54802,A6NDG6,P06737,Q7Z4W1,Q8TB61,P17252,Q8NCH0	35
Mitochondrial calcium ion transport	0.4572769572739424	1.1047744010190026	0.269257355414203	1.0	0.535062693451301	16	P21796	1
Signaling by wnt	0.3003062363601385	1.0934532484958353	0.2741948450892952	1.0	0.5430527779425222	88	P28072,P61289,Q99436,P31751,P20618,Q9UBL3,P49841,Q9HCE1,P25787,O75832,P63208,P30153,Q96QK1,P49720,P49721,P28074,Q16537,Q92530,Q13547,P07737,P28070,Q14997,P60900,Q9UBQ0,Q08209	25
Cyclin d associated events in g1	0.5208818157140692	1.0821493283266836	0.2791861799689854	1.0	0.5493152973076927	10	P30154,P63208,P63151,Q00534,P30153,P06400	6
Neutrophil degranulation	0.2802748636636091	1.0812690916713126	0.2795774320431519	1.0	0.5493152973076927	181	P17931,O15260,P04066,P42785,Q9BRF8,P20618,Q7L576,Q93050,Q969Q5,Q13464,P30519,Q9NQX7,Q07065,P06280,O15126,P63167,P10619,P16278,O60784,P42025,Q13576,P10253,P27105,Q4KMQ2,Q14019,Q99536,P07384,P14174	28
Runx1 regulates transcription of genes involved in differentiation of hscs	0.3582745529846506	1.0812637021843818	0.2795798287372486	1.0	0.5493152973076927	43	P28072,P28070,P20618,P49721,Q92530	5
Transport of vitamins nucleosides and related molecules	0.5663115224067491	1.0539665985956226	0.2918982096901814	1.0	0.567919110903491	7	P12235,P12236,Q8TB61	3
Peptide hormone metabolism	0.470145581915828	1.0370506031071236	0.2997122745168838	1.0	0.5807477970189273	13	P67812,Q15005	2
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein	0.4050976625773678	1.0324952797801088	0.301840157752369	1.0	0.5831953186489679	21	Q86YN1,P10619,Q9BT22,Q06210,P16278,O60547,Q9Y673,Q9Y223,Q2TAA5	9
Rho gtpases activate wasps and waves	0.3975100520188562	1.028715440327888	0.3036134121765221	1.0	0.5850009806439895	23	Q7L576,Q9Y2A7,Q9UQB8	3
Cell cycle	0.257770304202103	1.0254117897931554	0.3051689275448788	1.0	0.586378311191606	324	O75330,P49005,Q15005,Q8IXJ6,Q15554,P49643,P49721,P28074,Q92530,P35250,O96028,Q12769,Q92674,Q13547,P42695,P60900,Q99640,Q96DE5,Q6KC79,Q15021,P28072,Q86XI2,P00374,Q8NBT2,Q92621,Q96EE3,Q99436,Q9HBM1,P31751,P20618,P49841,Q86XL3,P63208,P50748,Q14739,Q9BZD4,Q9Y570,P49720,Q16537,Q96CW5,Q6IBW4,P63167,P28070,Q9P258,O43913,Q14997,Q12834,Q96RL1,Q9BTX1,Q9UBD5,P06400,P30876,Q9H6D7,P61289,Q07864,O95684,Q5SRE5,P21127,Q15003,Q00534,Q9BPX3,Q9NQS7,P25787,O75832,P09884,Q9UQ84,Q9UJX6,Q96BD8,Q8TD19,P30153,Q8WVM7,Q96SN8,Q9BS16,P41208,P62487,P42166,P04183,Q7Z5K2,P35251,P50402,P04818,O75935,O60566,Q9Y6X3,Q9UH99,Q9Y619,Q15154	87
Fcgamma receptor fcgr dependent phagocytosis	0.3587598748615357	1.0222045213175452	0.3066841113134977	1.0	0.5884791406909619	36	O43865,Q9UQB8,Q7L576,Q9Y2A7,Q8IV08	5
Synthesis of active ubiquitin roles of e1 and e2 enzymes	0.4917754436679506	1.0186271733353622	0.3083799987368172	1.0	0.5901098741260082	11	Q96BN8,Q93008,P49427	3
Transcriptional regulation by runx3	0.3512297417441929	1.011258816083996	0.3118925718826246	1.0	0.5943924353355791	43	P25787,Q06330,P28072,P61289,Q99436,P28070,P20618,P60900,P49720,P49721,P28074,Q92530	12
Diseases of mitotic cell cycle	0.4655055976537536	1.0095977946582542	0.3126880266443612	1.0	0.5950883999575497	13	Q9UJX6,Q00534,P06400	3
Tcr signaling	0.3306266506382234	0.992221822651804	0.3210893293710399	1.0	0.6077606709261882	53	P25787,P28072,P61289,P49427,Q16512,P63208,Q99436,P28070,Q14997,P20618,P19838,P60900,P49720,P49721,P28074,Q92530	16
Pp2a mediated dephosphorylation of key metabolic factors	0.4451628995445011	0.9739007221289856	0.3301058351623054	1.0	0.6200974206276307	3	P30153	1
Intraflagellar transport	0.4659842202987905	0.973561902941807	0.3302741100547166	1.0	0.6200974206276307	12	A0AVF1,P63167,Q8NCM8	3
Sema4d induced cell migration and growth cone collapse	0.5485162085712605	0.971327544374562	0.3313851966577199	1.0	0.6213472437332249	7	Q13464,P60660	2
Signaling by interleukins	0.2886924520916828	0.9638891228073192	0.3351015177609189	1.0	0.6270571509663931	110	Q13126,P28072,P09601,P05067,P28070,Q15833,Q14997,P20618,P49721,Q92530	10
Ikk complex recruitment mediated by rip1	0.4431274069541222	0.962811351901648	0.3356422028478252	1.0	0.6270571509663931	3	Q6SZW1	1
Plasma lipoprotein clearance	0.4571491408722629	0.960327652783247	0.3368903369314004	1.0	0.6282914706140423	13	P35610,Q8WTV0	2
Leishmania infection	0.3416575755859526	0.959155460692	0.3374804343101814	1.0	0.6285516767192296	46	O43865,P09601,P05067,Q9UQB8,Q9Y2A7	5
Disorders of transmembrane transporters	0.3055925357590287	0.9579717277156284	0.3380770151905112	1.0	0.628823248254351	76	P28072,P61289,Q9BUN8,Q92621,Q96EE3,Q5SRE5,Q99436,Q9UBV2,P20618,P25787,P11166,P53985,P49720,P49721,P28074,Q92530,Q12769,P28070,Q14997,P60900,Q9BTX1	21
Apc cdc20 mediated degradation of nek2a	0.4793766959718922	0.9505690848112592	0.3418231684830717	1.0	0.6315805563362715	11	O60566,Q9UJX6,Q12834	3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.4793766959718922	0.9505690848112592	0.3418231684830717	1.0	0.6315805563362715	11	O60566,Q9UJX6,Q12834	3
Downregulation of smad2 3 smad4 transcriptional activity	0.5572225310482944	0.946235551577161	0.3440284568715825	1.0	0.6348144144654202	6	Q93008,O75376	2
G2 m checkpoints	0.2872505982478291	0.9220160026468068	0.3565202285700861	1.0	0.6501251226866277	92	P28072,O96028,Q96RL1,P28070,Q92530,O43913,Q14997,P20618,Q9UBD5,P49721,Q99640	11
Regulation of mrna stability by proteins that bind au rich elements	0.3121418509270985	0.9196498542113752	0.3577557652956871	1.0	0.6515264916285685	66	P25787,P28072,P61289,Q14103,Q9NPI6,Q99436,P28070,Q13868,Q96B26,Q14997,P20618,Q9Y2L1,P60900,P49720,P49721,P28074,Q92530	17
Zbp1 dai mediated induction of type i ifns	0.5093353646468897	0.8948676720920716	0.3708578298989016	1.0	0.6684065538875552	5	Q9UHD2,Q13546	2
Notch hlh transcription pathway	0.507692100432602	0.8871877354307016	0.3749778344022134	1.0	0.6737524993224643	5	Q13547,O75376	2
Rac1 gtpase cycle	0.3322537783982218	0.8801064161583276	0.3788016636461195	1.0	0.6792137799310242	47	Q9UQB8,Q86VI3,P50402,P63167,P42166,Q14739,Q13576,Q7L576,Q9Y2A7,Q8IZP0,P11274	11
Fatty acid metabolism	0.3095141254907197	0.8705304522639776	0.3840105848470494	1.0	0.6859087911160486	58	Q15165,Q14914,O43772,P23786,P50897,Q9UMR5	6
Mrna decay by 3 to 5 exoribonuclease	0.4200753009929278	0.8675696240573082	0.3856299814333916	1.0	0.6870419209445484	16	Q13868,Q9Y2L1,Q6PGP7,Q969T7,Q96B26	5
Toll like receptor cascades	0.3594708144483784	0.8537592802230359	0.3932383806874664	1.0	0.6971249520658584	29	P50570,Q13546,Q6SZW1,P63208,Q9BQ95,P05067,Q9UHD2,P30153,P19838,Q99538	10
Binding and uptake of ligands by scavenger receptors	0.5215376567938619	0.8474775266000463	0.3967290082574939	1.0	0.7023311757857919	7	Q8WTV0	1
Regulation of lipid metabolism by pparalpha	0.3788275941975597	0.8406301454846723	0.400555165263341	1.0	0.7039268634783051	21	P23786,P50416,O75376,P04035,Q96EK7	5
Epha mediated growth cone collapse	0.505771563724331	0.8402824588585869	0.4007500341238803	1.0	0.7039268634783051	8	Q13464,P60660	2
Pten regulation	0.3061654286196275	0.8364155837874241	0.4029211486172812	1.0	0.7043546395001345	63	P28072,P28070,P31751,Q14997,P20618,P49721,Q92530	7
Polymerase switching on the c strand of the telomere	0.4067440889440714	0.8331392163566477	0.4047662185413307	1.0	0.7066944616585187	17	P49005,P40938,P09884,P49642,P28340,Q15554,P35251,P49643,P35250	9
Diseases associated with glycosylation precursor biosynthesis	0.5038039817709916	0.8309954537441373	0.4059761976316287	1.0	0.7079209946201527	8	P16278,P10619,Q9Y223	3
Fatty acyl coa biosynthesis	0.405739960551463	0.8266831316905684	0.4084166846981245	1.0	0.7104005924612017	17	P50897,Q9UMR5	2
Mismatch repair	0.4398401952175655	0.824705104653684	0.4095390329108674	1.0	0.7114656922922292	12	Q9UQ84,P49005	2
Signaling by notch1	0.4871526959763117	0.8229813354581746	0.4105186074629832	1.0	0.7122804196652507	9	Q13547,Q06330,Q96J02,O75376	4
Mitotic spindle checkpoint	0.3045183068344544	0.8135115352476479	0.4159248353851223	1.0	0.7180880511908981	61	Q15005,Q8NBT2,Q96EE3,Q9HBM1,Q9NQS7,O14777,P50748,Q9UJX6,P30260,Q96BD8,Q9BZD4,P30153,Q9BS16,O60566,Q16537,Q12769,Q92674,P63167,Q02224,Q9P258,Q14204,Q12834,Q96DE5	23
Ca2 pathway	0.5120576323000299	0.8045330906836378	0.4210891665046052	1.0	0.7243149041602026	7	Q08209,Q9HCE1	2
Recruitment of mitotic centrosome proteins and complexes	0.3342551294790272	0.8001223583119346	0.4236399082978086	1.0	0.7269098057508525	37	Q9H6D7,P17252,O95684,P21127,P07437,Q13409,Q99996,P61163,O75935,P30153,Q96SN8,Q9BSJ2,O94927,P41208,Q96CW5,P63167,P68371,Q14204,Q15154,P43034	20
Notch1 intracellular domain regulates transcription	0.5096671000075493	0.7937621703553939	0.4273338994102673	1.0	0.7288785467494877	7	Q13547,Q06330,O75376	3
Intracellular signaling by second messengers	0.2804232264149044	0.793649082618475	0.4273997499936064	1.0	0.7288785467494877	84	P28072,P61289,Q99436,P31751,P49840,P20618,P49841,Q9HCE1,P25787,O43865,O75832,Q96B36,P52292,P84095,P49720,P49721,P28074,Q16537,Q92530,Q13547,P46934,P28070,Q14997,P60900,Q13555	25
Trna modification in the nucleus and cytosol	0.4147077078777093	0.7892291371766375	0.4299780951049725	1.0	0.732098071347524	15	Q9H974,Q9UI30,Q96PZ0	3
Dna replication	0.2777737546949286	0.7886147325473675	0.4303372175662865	1.0	0.732098071347524	93	P28072,P61289,Q07864,P49005,Q99436,P49643,P20618,P35251,P25787,O75832,P63208,P09884,Q9UJX6,P40938,P30260,P49720,P49721,P28074,Q92530,P35250,O00231,P33993,P28070,P28340,Q9Y619,O43913,Q14997,P56282,P60900,P52294,Q96DE5,O75419,Q9UBD5	33
Resolution of sister chromatid cohesion	0.2997794497901401	0.7810704436473914	0.4347610643583173	1.0	0.7375570926266498	68	Q15005,Q8NFH4,Q8NBT2,Q96EE3,Q9NTI5,Q9HBM1,Q7Z5K2,O43684,Q9NQS7,O14777,Q13409,P50748,Q96BD8,Q9BZD4,P30153,Q8WVM7,Q9BS16,O60566,P53350,Q16537,P30154,Q12769,Q92674,P63167,Q02224,Q8WUM0,Q9P258,P68371,Q14204,Q9BVA1,O43264,Q13885,Q12834,O14980,O95067,O60216,P43034	37
Polymerase switching	0.4196154795793189	0.7785802690980231	0.4362270056573165	1.0	0.7375570926266498	14	P49005,P40938,P09884,P49642,P28340,P49643,P35251,P35250	8
Plasma lipoprotein assembly remodeling and clearance	0.4056712325192927	0.7777466357740951	0.436718393196855	1.0	0.7375570926266498	16	P35610,Q8WTV0	2
Cargo concentration in the er	0.4254871228125386	0.7765818499926888	0.437405513207693	1.0	0.7378242937421182	13	Q13190,Q15436,Q96PC5,Q9HCU5	4
Glycogen synthesis	0.515167014627351	0.7618731145136233	0.4461357376137136	1.0	0.7473720656400303	6	Q04446	1
Nr1h2 and nr1h3 mediated signaling	0.5148786420319494	0.7606317843713588	0.4468770297202828	1.0	0.7474741684170199	6	O75376	1
G protein mediated events	0.4429675950583073	0.7544060489451604	0.450605440508339	1.0	0.7509929523607786	11	O43865,P63096,P52292,P17252,Q13555	5
Activation of ampk downstream of nmdars	0.5127307581285383	0.7513980563865021	0.4524131320968467	1.0	0.7522244568237202	6	Q13885,Q13131,P68371	3
Initiation of nuclear envelope ne reformation	0.3842413261199649	0.7398454586274115	0.4593937720840273	1.0	0.7569438033162125	18	P50402,P42166,Q14739,Q86XL3	4
Intra golgi and retrograde golgi to er traffic	0.2739123380064405	0.7285445727969803	0.4662802939506076	1.0	0.7634518897430724	99	P53365,Q9H2M9,O15260,P20645,Q5VZE5,P63167,O75935,O60499,Q86Y91,Q9P2W9,Q13190,Q9NZ32,Q9Y678,O00461,Q96MW5,P84085,Q9NRW7	17
Apoptosis	0.2744937059945421	0.7272989723142835	0.4670428275494176	1.0	0.7638039207871483	90	P28072,Q13464,P63167,P28070,P31751,Q9UKG1,P20618,P49721,Q92530	9
Maturation of sars cov 2 nucleoprotein	0.5043673592152339	0.7156568275894052	0.4742032747667495	1.0	0.7683084416952561	6	P49840,P49841,Q96SB4	3
Selective autophagy	0.3345493749942116	0.7145558503117811	0.4748835337499018	1.0	0.7685180157553514	32	P21796,P63167,Q9NS69	3
Metabolism of folate and pterines	0.4635606113949377	0.7086484880474646	0.4785426385246558	1.0	0.7730871934427527	9	Q9H2D1	1
Cohesin loading onto chromatin	0.4476778164850581	0.7034484001616853	0.4817763527972332	1.0	0.7759425549989503	10	Q9Y6X3,Q8WVM7,Q7Z5K2	3
Conversion from apc c cdc20 to apc c cdh1 in late anaphase	0.4623105399966305	0.7026843710574602	0.4822524696660142	1.0	0.7759425549989503	9	Q9UJX6,Q12834	2
Ire1alpha activates chaperones	0.3465740977818997	0.6970186610962882	0.4857911154371295	1.0	0.7802521332122562	25	O14773,P61421,P49748,Q06210,P49840,O95070,Q14999,Q9HCU5	8
Chrebp activates metabolic gene expression	0.4658752860139907	0.6955317903922631	0.4867220956251166	1.0	0.7802521332122562	5	O00763,Q13085,P49327	3
Advanced glycosylation endproduct receptor signaling	0.4597389474300557	0.690449154145569	0.4899117745580437	1.0	0.7819530040142688	9	P05067	1
Peroxisomal protein import	0.3571293746440337	0.6868089216095632	0.4922031469692767	1.0	0.7847124457395896	21	Q9BY49,Q93008,O43933,Q9UJ83	4
Signaling by retinoic acid	0.4114678743840776	0.6679773310156223	0.5041480628431336	1.0	0.7973770381702624	12	Q8TC12,O94788	2
Negative regulation of nmda receptor mediated neuronal transmission	0.4925669883870459	0.6658636011849379	0.5054982877404364	1.0	0.7981927039588921	6	Q13555	1
Transcriptional regulation by mecp2	0.3996466976919784	0.6634039026620726	0.5070719070914085	1.0	0.7992828366017117	14	P42858,Q14739,O75376,Q13555,Q9HCE1	5
Synthesis of substrates in n glycan biosythesis	0.3784307703971362	0.6546958248825008	0.5126636139050058	1.0	0.8071848097037054	17	Q86YN1,P10619,Q06210,P16278,O60547,Q9Y223	6
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism	0.4563332708993213	0.6531345579956003	0.5136695350149774	1.0	0.8078568222614356	5	P30153,P17252	2
Rip mediated nfkb activation via zbp1	0.4231328942765697	0.6484432116358647	0.5166983293890046	1.0	0.8117051458306997	4	Q13546	1
Hyaluronan uptake and degradation	0.453891433953087	0.642386097588645	0.5206225241512721	1.0	0.8142022659092203	5	Q9UHD1,O75330,P08236	3
Hyaluronan metabolism	0.453891433953087	0.642386097588645	0.5206225241512721	1.0	0.8142022659092203	5	Q9UHD1,O75330,P08236	3
Egr2 and sox10 mediated initiation of schwann cell myelination	0.4440984512925938	0.6171095208750548	0.5371624892165578	1.0	0.8307557344313727	9	Q16850,Q9NR77	2
E2f enabled inhibition of pre replication complex formation	0.4790717437470422	0.609968372786655	0.5418827585628136	1.0	0.8336115396108649	6	O43913,Q9UBD5	2
Parasite infection	0.3290337948482706	0.6064362499017789	0.5442251031031056	1.0	0.8351969404057561	28	Q7L576,Q9Y2A7,Q9UQB8	3
Cell cycle checkpoints	0.2540889379086788	0.6049232232185986	0.5452300117973792	1.0	0.8358196334696086	153	P28072,O96028,Q12834,Q96RL1,Q92674,P50748,Q9UQ84,P63167,Q9UJX6,P28070,Q92530,O43913,Q14997,P20618,Q9UBD5,P49721,Q99640	17
Intrinsic pathway for apoptosis	0.3547532233426091	0.6007185803981147	0.5480274414287685	1.0	0.8382656587643991	19	P31751,P63167	2
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.4241460584968234	0.5884608616054634	0.5562229967728238	1.0	0.8489399130176031	10	Q9UJX6,P06400	2
Recruitment of numa to mitotic centrosomes	0.3090232693161031	0.5870689640854595	0.557157390609127	1.0	0.8493805519560785	40	Q9H6D7,P17252,O95684,P07437,Q13409,Q99996,P61163,O75935,P30153,Q96SN8,Q9BSJ2,O94927,P41208,Q96CW5,P63167,P68371,Q14204,Q9BVA1,Q15154,Q13885,P43034	21
Signaling by notch1 pest domain mutants in cancer	0.4485462768137754	0.5789845298736608	0.5625996117012695	1.0	0.8533879493333458	8	Q13547,Q06330,O75376	3
Tnf signaling	0.4484755298518963	0.5786759847654056	0.5628078232162568	1.0	0.8533879493333458	8	Q96EP0,Q96BN8	2
Condensation of prometaphase chromosomes	0.4152156288336019	0.5462219667463332	0.5849133681067817	1.0	0.881961280013806	10	Q9BPX3,Q15003,Q15021	3
Rho gtpases activate rocks	0.3878829652030666	0.5436102191298873	0.5867097260593634	1.0	0.881961280013806	12	O75116,Q13464,P60660	3
Transcriptional regulation by runx1	0.2783821321009448	0.5419356664516056	0.5878628254082061	1.0	0.8827434245903633	70	P17931,P28072,Q9HCL2,P28070,Q00534,Q14997,P20618,Q9UBL3,P49721,Q92530	10
Crmps in sema3a signaling	0.4280273604618905	0.5314991240430307	0.5950729481560768	1.0	0.890693951370952	5	Q00535,P49841	2
Dual incision in gg ner	0.3263476501977229	0.5282395575941665	0.5973330768709995	1.0	0.892270979768248	24	Q07864,P49005,Q16531,Q92759,P28340,P35251,P19447,P35250	8
Phase ii conjugation of compounds	0.3182765543735359	0.5258944780626911	0.5989615257892702	1.0	0.892270979768248	28	P78417,Q99707,P48507,Q8WUX2,O43252,Q9NX62,Q9UI30,Q9NUJ1	8
Metalloprotease dubs	0.4475112079204515	0.5255294266493435	0.5992152024120081	1.0	0.892270979768248	7	Q96RL1	1
Costimulation by the cd28 family	0.3746190651650408	0.5253719265958622	0.5993246652636905	1.0	0.892270979768248	14	P31751,P30153,Q16512,Q16537	4
Apc c cdc20 mediated degradation of cyclin b	0.3976451418500683	0.5239901603860743	0.6002853836397306	1.0	0.8927485183128189	11	Q9UJX6,Q12834	2
Glutathione synthesis and recycling	0.4571620421905914	0.5220836918121708	0.6016120606679736	1.0	0.8937687163278202	6	P48507	1
Protein ubiquitination	0.3180201872057669	0.5175690587830406	0.6047589743931847	1.0	0.8958632566707067	27	P78527,P49427,Q9BUN8,Q96BN8,Q14527,Q6PD62,P50542,Q93008	8
Nuclear signaling by erbb4	0.3942447797649364	0.5172974674115858	0.6049485217088213	1.0	0.8958632566707067	4	O75376	1
Rho gtpases activate formins	0.2758524823047545	0.4978175895272447	0.6186126170773061	1.0	0.907778732394054	65	Q15005,Q8NFH4,Q8NBT2,Q96EE3,Q9HBM1,O43684,Q9NQS7,O14777,Q13409,P50748,Q96BD8,Q9BZD4,Q9NSV4,P30153,Q9BS16,O60566,P53350,Q16537,P30154,Q12769,Q92674,P63167,P07737,Q02224,Q8WUM0,Q9P258,P68371,Q14204,Q9BVA1,O43264,Q13885,Q12834,O14980,P43034	34
Metabolism of vitamins and cofactors	0.288566214633878	0.4971528596604666	0.6190812611633181	1.0	0.907778732394054	50	Q8TC12,P78417,Q6NUM9,P00374,Q99707,P09455,O96007,Q9H2D1,Q8N0U8,Q9BQG2,Q9HC21	11
Arms mediated activation	0.317521494218795	0.496778837481582	0.6193450202703248	1.0	0.907778732394054	2	P46108	1
Signaling by erbb4	0.4286543468885678	0.4941327474243044	0.6212124318807153	1.0	0.9083766692595364	8	P46934,O75376,P61201	3
Assembly and cell surface presentation of nmda receptors	0.4020804758250411	0.4857813952270822	0.6271221665701101	1.0	0.9141435970379348	10	Q13885,O14936,P68371,Q13555	4
Unwinding of dna	0.4143283374801726	0.4837945539912783	0.6285316804660384	1.0	0.9150175142502152	9	P33992,P33993,P49736,O75419,Q14566	5
Gluconeogenesis	0.3358974091705347	0.4830875894529156	0.6290335456386784	1.0	0.9150175142502152	19	Q9UBX3	1
Darpp 32 events	0.4011057776437289	0.4813836817353233	0.6302438322749022	1.0	0.9158230687744672	10	Q08209,P30153,Q00535,P10644,P17252	5
Host interactions of hiv factors	0.2547254599454367	0.4671402173756147	0.6403995620614624	1.0	0.920038505742266	96	P28072,Q9BTX1,P28070,Q14997,P20618,P12235,P49721,Q92530	8
Miscellaneous transport and binding events	0.4321225758510981	0.4639771993111009	0.642664081393306	1.0	0.9205579459496588	7	Q8N4V1,P35612	2
Activation of nima kinases nek9 nek6 nek7	0.4094750456698571	0.4559426606007187	0.6484312113308006	1.0	0.9212926553482508	5	Q8TD19,O95067	2
Signaling by notch	0.2715583685442317	0.4529349507366221	0.6505955827481655	1.0	0.9212926553482508	60	P25787,Q06330,P28072,P61289,P63208,Q13547,Q96J02,Q99436,P28070,Q9UBV2,Q92530,O75376,P20618,P60900,P49720,P49721,P28074,Q9HCE1	18
Potential therapeutics for sars	0.2939382038911518	0.4528720482213789	0.6506408794402851	1.0	0.9212926553482508	38	Q99720	1
Activation of bh3 only proteins	0.3825272655419416	0.452461701209705	0.6509364058375524	1.0	0.9212926553482508	11	P31751	1
Myd88 independent tlr4 cascade	0.3173098740283624	0.4506023308330959	0.6522761864454991	1.0	0.9219101115415108	23	Q13546,Q6SZW1,P63208,P05067,Q9UHD2,P30153,P19838	7
Syndecan interactions	0.4063207213554015	0.4434852753937948	0.6574147673650428	1.0	0.9254224020930724	5	O14936,P17252,Q9Y296	3
Transcriptional regulation by ventx	0.3665219268914123	0.4374866090426618	0.6617584854197818	1.0	0.9262794803564008	12	Q9UJX6,P19838,Q96DE5,Q9HCE1	4
Cilium assembly	0.2689885465519778	0.4319794851018192	0.6657563234696553	1.0	0.9262794803564008	68	Q9H6D7,P17252,Q8NCM8,Q15051,O95684,A6NIH7,P07437,O60645,Q99996,P61163,Q10713,O75935,P30153,Q96SN8,Q7Z4L5,O94927,P41208,P49368,P50991,P63167,P68371,Q14204,Q96KP1,Q9BVA1,Q15154,Q13885,Q9H0F7,A0AVF1,P43034,Q92538	30
Unfolded protein response upr	0.2891064928481728	0.4271170836150881	0.6692940504630078	1.0	0.9262794803564008	42	O14773,P61421,P08243,P49748,Q06210,P49840,Q13868,O95070,Q9Y2L1,Q14999,Q96B26,Q9HCU5	12
Assembly of the hiv virion	0.3708764684600554	0.4181918935275341	0.6758068222449447	1.0	0.9262794803564008	4	Q9NZ09,Q9H9H4	2
Stat5 activation downstream of flt3 itd mutants	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Pi 3k cascade fgfr2	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Regulation of kit signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	P17252	1
Frs mediated fgfr1 signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Pi 3k cascade fgfr1	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Pi 3k cascade fgfr4	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Tie2 signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Frs mediated fgfr4 signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Pi 3k cascade fgfr3	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Frs mediated fgfr3 signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Shc1 events in erbb2 signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	P17252	1
Frs mediated fgfr2 signaling	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Signaling by flt3 itd and tkd mutants	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Egfr transactivation by gastrin	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	P17252	1
Stat5 activation	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Activated ntrk2 signals through frs2 and frs3	0.3012155351319268	0.4152708750506158	0.677943619673036	1.0	0.9262794803564008	2	Q06124	1
Dna double strand break response	0.3151557613935229	0.4116327171175152	0.6806086474688215	1.0	0.9290108250675206	21	O95677,O96028	2
Programmed cell death	0.2511726866377611	0.4084068915261945	0.6829749747469609	1.0	0.9302054037947142	102	P28072,Q13464,P63167,P28070,P31751,Q9UKG1,P20618,P49721,Q92530	9
Cytosolic sensors of pathogen associated dna	0.3295925978591206	0.4071799747741357	0.683875808249502	1.0	0.9302054037947142	18	P78527,Q13546,Q9UHD2,Q9BUI4,Q9UJV9,P19838	6
Inactivation of csf3 g csf signaling	0.3964391691394682	0.4052678800290514	0.6852806138728298	1.0	0.9302806460888624	5	P42224,P40763,Q93034,Q15369	4
Disinhibition of snare formation	0.3297746144721237	0.3922453396732465	0.6948769465954803	1.0	0.9374790527086024	3	P17252,O00186	2
Recognition of dna damage by pcna containing replication complex	0.311059897468185	0.3870502893195678	0.698718978241283	1.0	0.941134793565075	21	Q07864,P49005,Q16531,P40938,P28340,P35251,P56282,P35250	8
G alpha z signalling events	0.4207788586996638	0.3861642744313052	0.699375010379355	1.0	0.941134793565075	6	P17252,P08754,P63096	3
Carboxyterminal post translational modifications of tubulin	0.3911009555893359	0.3851600111823726	0.700118868585403	1.0	0.941134793565075	5	Q13885,P68371	2
E2f mediated regulation of dna replication	0.3503480567687337	0.3799530382166277	0.7039802755588715	1.0	0.9433741444809086	13	P09884,Q9Y619,O43913,P49643,Q9UBD5,P06400	6
Metabolism of water soluble vitamins and cofactors	0.2822641438119685	0.3679607131579492	0.7129025285066131	1.0	0.951028723063436	41	P78417,P43490,P00374,Q99707,O96007,Q9H2D1,Q9BQG2,Q9HC21,Q9NVE7	9
Mitotic telophase cytokinesis	0.3474122191282761	0.3662983391521792	0.7141424687751416	1.0	0.951028723063436	13	Q9NTI5,Q6KC79,Q7Z5K2,O95235,Q8WVM7,O60216,Q9Y6X3	7
Adrenaline noradrenaline inhibits insulin secretion	0.3571640462770803	0.3636854553099639	0.7160929056580765	1.0	0.9512274379213248	4	P63218,P04899,P63096	3
Aurka activation by tpx2	0.2822765773682064	0.3609715475823969	0.7181207168310608	1.0	0.951356505203542	36	P41208,Q13409,O75330,Q9H6D7,Q99996,P17252,P61163,O95684,P63167,O75935,P68371,P30153,Q14204,Q96SN8,P07437,Q15154,P43034,O94927	18
Synthesis of pips at the golgi membrane	0.4018504376342213	0.350923548592998	0.725645704366725	1.0	0.952637114593952	7	Q10713,Q9NTJ5,Q9UBF8	3
Sensory perception	0.2936523313935844	0.3504906144436608	0.7259705326060937	1.0	0.952637114593952	27	Q8TC12,P50579,Q6NUM9	3
Rab geranylgeranylation	0.2990677661146305	0.3503905341645804	0.726045629335176	1.0	0.952637114593952	24	Q969Q5,P53611	2
Cdc42 gtpase cycle	0.2802427247171686	0.3469003317847409	0.7286661973807147	1.0	0.952637114593952	35	P63167,P42166,P27105,Q14739,Q13576,Q9UQB8,P11274	7
Rhog gtpase cycle	0.277661401207332	0.328192579310513	0.7427660582562656	1.0	0.9629727242262924	35	Q86XL3,O15173,P50402,P42166,Q14739,Q96JJ3,Q13190,P49257,Q13576,Q7L576	10
Signaling by cytosolic fgfr1 fusion mutants	0.3824210453666478	0.3154359430327417	0.7524306801269107	1.0	0.9674108744488852	8	O95684,O15164	2
Establishment of sister chromatid cohesion	0.3792608005120657	0.3043756666886041	0.7608417040527855	1.0	0.9755277363544446	8	Q8WVM7	1
Dna double strand break repair	0.2555503756521914	0.3021497703255185	0.7625378931310589	1.0	0.9768047391348276	59	P78527,O96028,P49005,Q96RL1,O95677,Q9UQ84	6
Butyrate response factor 1 brf1 binds and destabilizes mrna	0.330854711217376	0.2928941894185491	0.7696030303658112	1.0	0.9831467283519292	13	Q9NPI6,Q13868,Q96B26	3
Pi3k akt signaling in cancer	0.3446349616351255	0.2901135431068713	0.7717293752469667	1.0	0.9834883608584144	11	P31751,P49841	2
Telomere c strand lagging strand synthesis	0.2856003121881221	0.2838785656865377	0.7765034431486946	1.0	0.9834883608584144	25	P49643,P49005,P35251,Q15554	4
Purine salvage	0.3621079479991069	0.2833762186094514	0.7768884563636695	1.0	0.9834883608584144	5	P00813	1
Semaphorin interactions	0.2895650146508897	0.2832838314739571	0.7769592704852517	1.0	0.9834883608584144	23	P60660,Q9BPU6,Q13464,Q00535,O75116,O94887,P49841	7
Gab1 signalosome	0.3013048635824448	0.2773493529666486	0.7815118671064583	1.0	0.9834883608584144	3	P41240,Q06124	2
Dna strand elongation	0.2809684350153298	0.2743243366447298	0.7838353836735603	1.0	0.9834883608584144	29	P49005,P33993,P40938,P09884,P49642,P28340,O75419,P49643,P35251,P35250	10
Platelet sensitization by ldl	0.3866767244381779	0.27357240023054	0.7844132465115852	1.0	0.9834883608584144	6	P30153,Q16537	2
Tristetraprolin ttp zfp36 binds and destabilizes mrna	0.3215756753329806	0.2693258986775972	0.7876789039796237	1.0	0.9834883608584144	14	Q9NPI6,Q13868,Q96B26	3
G beta gamma signalling through cdc42	0.3572700296736012	0.2677318686147865	0.7889057174197269	1.0	0.9834883608584144	5	P63218,Q13153,P60953,Q16512	4
Adp signalling through p2y purinoceptor 12	0.3572700296735877	0.2677318686147432	0.7889057174197602	1.0	0.9834883608584144	5	P63218,P08754,P04899,P63096	4
Gaba b receptor activation	0.3572700296735877	0.2677318686147432	0.7889057174197602	1.0	0.9834883608584144	5	P63218,P08754,P04899,P63096	4
Gaba receptor activation	0.3572700296735877	0.2677318686147432	0.7889057174197602	1.0	0.9834883608584144	5	P63218,P08754,P04899,P63096	4
Copi dependent golgi to er retrograde traffic	0.2610434442244024	0.2611142244093	0.7940044226081664	1.0	0.988078652576621	50	O15260,Q9P2W9	2
Activation of nmda receptors and postsynaptic events	0.2831489129889538	0.2582232730332373	0.7962345975616958	1.0	0.9886040627102826	24	Q13885,Q13131,Q14012,O14936,P68371,P52292,P10644,P17252,Q13555	9
Dna replication pre initiation	0.250283136890931	0.2489792701583129	0.8033768165932749	1.0	0.9926000237973444	67	P28072,P28070,O43913,Q14997,P20618,P49721,Q92530	7
P130cas linkage to mapk signaling for integrins	0.2924080664294194	0.2451884599448133	0.8063105113562072	1.0	0.992805195648401	3	Q05397,P46108	2
Dna damage bypass	0.2762383352722701	0.2446773323348364	0.806706280812375	1.0	0.992805195648401	27	Q07864,Q15004,P49005,Q16531,P28340,Q92890,P35251,P56282,P35250	9
Microrna mirna biogenesis	0.3215005070952987	0.2423900767518055	0.808477922764576	1.0	0.992805195648401	12	O75569,P62487	2
Cd209 dc sign signaling	0.3747398591176547	0.2382461829620615	0.811690159337314	1.0	0.9941683481068024	6	P19838,Q16512	2
Translesion synthesis by y family dna polymerases bypasses lesions on dna template	0.2811031723728857	0.2378354498732203	0.8120087224177794	1.0	0.9941683481068024	23	Q07864,Q15004,P49005,P28340,Q92890,P35251,P56282,P35250	8
Nicotinate metabolism	0.3194955343032779	0.2311287704465292	0.817214764580499	1.0	0.9947650427962876	4	Q9BQG2	1
Purine ribonucleoside monophosphate biosynthesis	0.3366089404607363	0.2252719336484797	0.8217677322457348	1.0	0.9959896174090044	10	Q06203,P20839,P30520,P31939,P22102	5
Mapk1 erk2 activation	0.2861803084223025	0.2238457312567274	0.8228773443225352	1.0	0.9959896174090044	3	P36507,Q06124	2
Rho gtpases activate iqgaps	0.3267153710409683	0.223727933720132	0.822969008873913	1.0	0.9959896174090044	11	Q13885,Q13576,Q86VI3,P68371	4
Atf4 activates genes in response to endoplasmic reticulum stress	0.3128513433797547	0.2207977260956426	0.825249934202748	1.0	0.9959896174090044	13	Q13868,Q96B26,P08243	3
Interconversion of nucleotide di and triphosphates	0.2923798815106251	0.2206685310728361	0.8253505360034474	1.0	0.9959896174090044	18	Q9NRF8,P04818,Q9Y3D8,P17812,P23921	5
Ca dependent events	0.3601335000068999	0.2171128726956067	0.8281203822715275	1.0	0.9976061599903115	7	P17252,P52292,Q13555	3
Amino acids regulate mtorc1	0.3123916431383861	0.2087887590283079	0.834613146946471	1.0	1.0	12	Q9UI12,P21281,P61421	3
Tgf beta receptor signaling activates smads	0.3471933471933441	0.202213892736239	0.8397495126448089	1.0	1.0	8	Q9Y4E8,Q9Y3F4,Q9UNE7,Q9Y5K5,O14980,P62136,P62140	7
Signaling by wnt in cancer	0.3385746322700119	0.2016443121577371	0.8401948006234916	1.0	1.0	9	P30153,P49841,Q16537	3
Inhibition of replication initiation of damaged dna by rb1 e2f1	0.3520938256716306	0.19476727237543	0.8455751444548889	1.0	1.0	7	P09884,P30153,P49643,P06400	4
Regulation of insulin secretion	0.3024152874701748	0.1937920146741365	0.8463387398523179	1.0	1.0	14	P11166,O43865,P63096,O95573,P17252	5
Translation of sars cov 1 structural proteins	0.3508825775598936	0.1915048457948408	0.8481300844040705	1.0	1.0	7	P49841	1
Downregulation of tgf beta receptor signaling	0.3491686460807625	0.1869356635619295	0.8517110765675115	1.0	1.0	7	Q9Y4E8,Q9Y3F4,Q9UNE7,Q9Y5K5,O14980,P62136	6
Diseases of dna repair	0.3148982826341591	0.1841995449246765	0.8538569164700254	1.0	1.0	11	Q9UQ84	1
Rab regulation of trafficking	0.255586679113521	0.1787330273953037	0.8581473346297182	1.0	1.0	38	Q9H2M9,Q5VZ89,Q9Y296,Q4KMP7,P31751,Q15276,Q9Y3P9	7
Signaling by scf kit	0.3437897510647004	0.1729582787452693	0.862684222045262	1.0	1.0	7	P17252,Q06124,O14757	3
Rho gtpase cycle	0.2282208050046099	0.1683166906301263	0.866334143959826	1.0	1.0	167	Q03001,Q13505,P28288,Q7L576,O94887,Q8IZP0,Q86XL3,O43396,Q8NBN3,Q13464,P30519,Q9NNW5,P50402,Q14739,Q96JJ3,Q13190,Q07065,P84095,Q9Y2A7,Q93008,P11274,Q5VTR2,Q8WWQ0,Q99707,O15173,P63167,P42166,Q9UDY2,Q9HD26,Q13576,Q9UQB8,P12277,O75976,Q9BST9,Q9Y512,Q86VI3,P27105,P61201,P49257	39
Anchoring of the basal body to the plasma membrane	0.2533447705584267	0.1662702335495441	0.8679442901418029	1.0	1.0	37	P41208,Q13409,Q9H6D7,Q99996,P17252,P61163,Q15051,O95684,P63167,O75935,P68371,P30153,Q14204,Q96SN8,P07437,Q15154,P43034,O94927	18
Transcriptional activity of smad2 smad3 smad4 heterotrimer	0.3123246433856294	0.1511297415849617	0.879873371557802	1.0	1.0	10	Q93008,O75376	2
Mapk3 erk1 activation	0.2886383862355449	0.1447610956195729	0.8848994997952286	1.0	1.0	4	Q02750,Q06124,P27361	3
Formation of tubulin folding intermediates by cct tric	0.2921950098027182	0.142494883855466	0.8866891202288845	1.0	1.0	12	Q13885,P50990,P49368,P50991,P68371,Q9BVA1	6
Sars cov 1 infection	0.2816310296830811	0.1331984917753967	0.8940364036083546	1.0	1.0	15	P49841,P06400	2
Dscam interactions	0.2835953722930976	0.1327400929055653	0.8943989338595315	1.0	1.0	4	Q13153,P63000,Q16512	3
Antigen presentation folding assembly and peptide loading of class i mhc	0.2829198040331236	0.1283247923076591	0.8978919458794272	1.0	1.0	14	Q9NZ08,Q03518	2
Negative regulation of mapk pathway	0.2869461790068491	0.1272013310145017	0.8987810519427075	1.0	1.0	12	Q99956,P30154,P31946,Q02750,P36507,P30153,P27361,Q14738,P30086,P53041,Q16537	11
Nucleotide salvage	0.3178236294807451	0.126441118528816	0.8993827554389207	1.0	1.0	8	P04183,P00813	2
Nuclear events kinase and transcription factor activation	0.2843545508625726	0.1254583438737968	0.9001607011892754	1.0	1.0	13	P50570,P30154,Q8IV63,Q14839,P28482,P30153,P27361,P51812,Q00535,P51452,Q14738,Q15418	12
Signaling by braf and raf1 fusions	0.2565351957449374	0.1236876174403873	0.9015626162209978	1.0	1.0	23	Q9NRY5,O43252,O15164	3
Global genome nucleotide excision repair gg ner	0.2455498129547279	0.1209844573415135	0.90370334600195	1.0	1.0	41	P41208,Q07864,P49005,Q16531,Q92759,P40938,P28340,P61201,P35251,Q7L5N1,P56282,P19447,Q9BT78,P35250	14
Flt3 signaling in disease	0.3014836795252313	0.1196636039674446	0.904749632956082	1.0	1.0	5	Q92614,Q06124,Q01082,Q14789	4
Response of mtb to phagocytosis	0.2815259101345821	0.1173390060209595	0.9065914161759896	1.0	1.0	13	Q9UI12,P23246,P49840	3
Infection with mycobacterium tuberculosis	0.2815259101345821	0.1173390060209595	0.9065914161759896	1.0	1.0	13	Q9UI12,P23246,P49840	3
Perk regulates gene expression	0.276231947007066	0.1163663830280034	0.9073621768154988	1.0	1.0	15	Q13868,Q96B26,P08243	3
Glucose metabolism	0.2316053490384796	0.1143163666534893	0.9089870088367312	1.0	1.0	59	P09972,P53007,Q12769,Q9BRR6,Q92621,Q96EE3,Q5SRE5,Q9BTX1,Q8WUM0,A6NDG6,Q9UBX3,P08237,P30153,P52789,P19367,P17252	16
Homology directed repair	0.2399546702087597	0.0964536788259502	0.9231602612736298	1.0	1.0	45	O96028,P49005,Q96RL1	3
Metabolism of nitric oxide nos3 activation and regulation	0.3135086745005445	0.096001009814238	0.9235197705527278	1.0	1.0	6	Q9Y314	1
Cargo trafficking to the periciliary membrane	0.249740390033459	0.0944583876926604	0.9247450364092756	1.0	1.0	22	P49368,P50991,Q10713,A6NIH7,Q9H0F7,Q96KP1,O60645,Q92538	8
Ion homeostasis	0.2816864121221595	0.0928026169950934	0.9260603719239991	1.0	1.0	11	O43865	1
Negative regulation of fgfr1 signaling	0.2863501483679604	0.0904806384884982	0.9279052790858362	1.0	1.0	5	Q06124,P27361,P30153,P62993	4
Negative regulation of fgfr3 signaling	0.2863501483679604	0.0904806384884982	0.9279052790858362	1.0	1.0	5	Q06124,P27361,P30153,P62993	4
Spry regulation of fgf signaling	0.2863501483679604	0.0904806384884982	0.9279052790858362	1.0	1.0	5	Q06124,P27361,P30153,P62993	4
Negative regulation of fgfr4 signaling	0.2863501483679604	0.0904806384884982	0.9279052790858362	1.0	1.0	5	Q06124,P27361,P30153,P62993	4
Negative regulation of fgfr2 signaling	0.2863501483679604	0.0904806384884982	0.9279052790858362	1.0	1.0	5	Q06124,P27361,P30153,P62993	4
Vitamin b5 pantothenate metabolism	0.2859289093161231	0.089736503090685	0.9284966076752688	1.0	1.0	5	Q9NVE7,P49327	2
Loss of function of mecp2 in rett syndrome	0.3082344142400642	0.0869618762467985	0.9307018156121948	1.0	1.0	6	Q13547,O75376	2
Mapk targets nuclear events mediated by map kinases	0.284101040118873	0.0831553375919665	0.9337280251275206	1.0	1.0	10	P30154,Q8IV63,P28482,P30153,P27361,P51812,P51452,Q14738,Q15418	9
Erk mapk targets	0.284101040118873	0.0831553375919665	0.9337280251275206	1.0	1.0	10	P30154,Q8IV63,P28482,P30153,P27361,P51812,P51452,Q14738,Q15418	9
Signaling by csf3 g csf	0.3016627078384784	0.0830915818747163	0.9337787193908452	1.0	1.0	7	Q06124,Q93034,P42224,Q15369,Q15370,P40763	6
Defects in biotin btn metabolism	0.3051350549124402	0.0818880588324369	0.934735730218238	1.0	1.0	6	P11498,Q9HCC0,P05166,Q96RQ3,Q13085	5
Peroxisomal lipid metabolism	0.2659482135749357	0.0770974529815568	0.9385460191977162	1.0	1.0	13	Q9BY49,Q9UJ83	2
Depolymerisation of the nuclear lamina	0.2867344281357163	0.0755032996934825	0.9398142722571396	1.0	1.0	9	P42166	1
Rho gtpase effectors	0.2195292096377974	0.0676633636704784	0.9460536139992266	1.0	1.0	130	Q15005,Q8NBT2,Q16512,Q96EE3,Q9HBM1,Q9NQS7,Q7L576,Q8IZP0,O43663,P50748,Q13464,Q96BD8,Q9BZD4,P30153,Q9BS16,P84095,O60566,Q9Y2A7,Q16537,Q12769,Q92674,P63167,P07737,Q9P258,Q9HD26,O75116,Q9UQB8,Q13576,Q9BST9,Q12834,P60660,Q86VI3	32
Cardiac conduction	0.2623198155548891	0.0664095866912237	0.9470517379777176	1.0	1.0	12	P17252,O43865,Q99996,Q13555	4
Cooperation of pdcl phlp1 and tric cct in g protein beta folding	0.2610764198632221	0.0638177415502833	0.9491153513402336	1.0	1.0	12	P50990,P49368,P50991,P67870,P78371,P17987,P19784,P63218,Q99832,Q9UBI6,P48643	11
Integrin signaling	0.2926684476105718	0.0632318448596196	0.9495818869781764	1.0	1.0	6	P18031,Q05397,P41240,P62993,P46108	5
Platelet aggregation plug formation	0.2926684476105718	0.0632318448596196	0.9495818869781764	1.0	1.0	6	P18031,Q05397,P41240,P62993,P46108	5
Signaling by ptk6	0.2605879065125726	0.0628118160820293	0.9499163565774916	1.0	1.0	12	P23246,Q07666,Q96JJ3,P20936,P46108	5
Copi independent golgi to er retrograde traffic	0.2385341305775546	0.0627644857248264	0.9499540463722702	1.0	1.0	29	Q13885,Q9H2M9,P47756,P61163,Q8TD16,P63167,O75935,P68371,Q9UJW0,Q14204,Q9NZ32,Q9BVA1,P43034,Q10472	14
Regulation of plk1 activity at g2 m transition	0.233993438930908	0.0625186205180018	0.9501498339156124	1.0	1.0	41	Q9H6D7,O95684,P43034,P07437,Q13409,Q99996,P61163,P63208,O75935,P30153,Q96SN8,O94927,P41208,P63167,P68371,Q14204,Q15154,O95067,P17252	19
Raf independent mapk1 3 activation	0.2865201900237522	0.0593155388306399	0.9527007847090524	1.0	1.0	7	P06493,Q06124,Q02750,P36507,P27361,Q99956	6
Erks are inactivated	0.2865201900237512	0.0593155388306385	0.9527007847090536	1.0	1.0	7	P30154,Q8IV63,P30153,P27361,P51452,Q14738	6
Tbc rabgaps	0.2492269988209464	0.0576432877239724	0.9540327683588914	1.0	1.0	17	Q4KMP7,Q9Y3P9,Q15276	3
Glycolysis	0.2302389294101068	0.0547526006189266	0.9563355629438126	1.0	1.0	48	P09972,Q12769,Q9BRR6,Q92621,Q96EE3,Q5SRE5,Q9BTX1,Q8WUM0,A6NDG6,P08237,P30153,P52789,P19367,P17252	14
Signaling by hippo	0.2819018877343213	0.0529293781224524	0.9577881768407162	1.0	1.0	7	Q4VCS5	1
Phosphorylation of the apc c	0.2615328255540738	0.0519183107697108	0.9585937840673548	1.0	1.0	11	P30260,Q9UJX6,Q9UJX2,Q96DE5	4
Signaling by nuclear receptors	0.2219468666388785	0.0479839138622123	0.9617290627171402	1.0	1.0	62	Q8TC12,P62487,Q9HCL2,O94788,P31751,Q8WVM7,P50416,O75376,Q9HCE1	9
Transport to the golgi and subsequent modification	0.2210783643400913	0.0466553713187233	0.9627879001122096	1.0	1.0	75	P04066,Q9UJW0,O95249,O00743,Q9HCU5,P61163,O75935,Q15436,Q13190,P84085,O95487,P47756,Q8IUR0,Q96PC5,O15027,P63167,P68371,Q9H0U4,Q9Y6Y8,Q14204,Q9NZ32,Q13885,P53621,Q9Y296,Q9H9E3,O94979,Q9Y678,Q96MW5,P49257,Q92538,Q5H9R7	31
Er to golgi anterograde transport	0.2225610935918576	0.0463040895905332	0.9630678797855968	1.0	1.0	73	Q9UJW0,O95249,O00743,Q9HCU5,P61163,O75935,Q15436,Q13190,P84085,O95487,P47756,Q8IUR0,Q96PC5,O15027,P63167,P68371,Q9H0U4,Q9Y6Y8,Q14204,Q9NZ32,Q13885,P53621,Q9Y296,Q9H9E3,O94979,Q9Y678,Q96MW5,P49257,Q92538,Q5H9R7	30
Postmitotic nuclear pore complex npc reformation	0.2340654354414482	0.0440000606235912	0.9649043555450731	1.0	1.0	22	Q92621,Q96EE3,Q12769,Q9BTX1	4
Signaling by receptor tyrosine kinases	0.2180034302452752	0.0396238635681322	0.9683930020001374	1.0	1.0	122	Q13685,O43865,P62487,P61421,Q9UI12,P46934,Q13464,Q7L576,P21281,Q9Y2A7,P61201,P31751,Q8IZP0,Q9UQB8,Q93050,O75376,P42566	17
Fanconi anemia pathway	0.2678084095105034	0.0392155178381948	0.9687185617074046	1.0	1.0	8	Q9BXW9	1
Folding of actin by cct tric	0.2607662607662608	0.0309677792667557	0.9752952357624236	1.0	1.0	8	P50990,P49368,P50991,P78371,P17987,Q99832,P48643	7
Rnd2 gtpase cycle	0.2421063306834199	0.0309447165182496	0.9753136283585604	1.0	1.0	14	O43396,Q9NNW5,Q07065	3
Nephrin family interactions	0.2551990493167029	0.0284062152132123	0.9773381671796676	1.0	1.0	9	P46940,P16333,O43707,Q01082,O00401,O14936,Q13813,P12814	8
Signaling by tgfb family members	0.2274140199821209	0.0266801346888095	0.9787148577139516	1.0	1.0	21	Q93008,O75376,Q7Z3T8	3
Alpha linolenic omega3 and linoleic omega6 acid metabolism	0.2585345657908424	0.026431460001355	0.978913201457859	1.0	1.0	7	Q15067,O95864	2
Metabolism of amino acids and derivatives	0.2168858180114981	0.0193196956072179	0.9845860720379628	1.0	1.0	197	Q13126,Q02252,P28072,P35610,P28070,P61313,Q9UBX3,Q14997,P57772,P20618,P78330,Q9NR77,P49721,P27635,Q92530	15
Bbsome mediated cargo targeting to cilium	0.2478103294239283	0.0181011344332635	0.9855581729536635	1.0	1.0	8	P49368,Q9H0F7,P50991	3
Mhc class ii antigen presentation	0.2155425902036039	0.0147032264791291	0.988268945279259	1.0	1.0	55	P50570,Q9UJW0,Q00610,Q13409,P61163,O75935,Q15436,O95487,P47756,P63167,P10619,Q02224,P68371,Q10567,Q14204,Q9NZ32,P42025,Q9BVA1,Q99538,Q13885,O94979,O95235	22
Gap junction degradation	0.2429934163634488	0.0142926231865189	0.9885965248759884	1.0	1.0	6	P50570,Q00610	2
Cytokine signaling in immune system	0.2159071549594914	0.0131326878589797	0.989521932304016	1.0	1.0	175	Q13126,P28072,P14174,P09601,Q9BTX1,P05067,P28070,Q15833,P31751,Q14997,P20618,P49721,Q92530	13
Integration of energy metabolism	0.2213310432227991	0.0112595518305907	0.991016367253641	1.0	1.0	24	P11166,O43865,P63096,O95573,O00763,P30153,P49327,P10644,P17252,P53396,Q13085	11
Raf activation	0.228489552201793	0.0071033373568335	0.9943324044548724	1.0	1.0	11	Q13555,Q16537	2
Mitotic prophase	0.2143199998445133	0.0065831229039816	0.9947474658116956	1.0	1.0	63	Q86XI2,Q9BTX1,Q6IBW4,Q8TD19,P42695,P06400	6
Autophagy	0.2166014685034443	0.0063070172386921	0.994967761683006	1.0	1.0	52	Q15388,Q9Y4P8,P63167,Q8N4H5,P21796,Q9NS69	6
Cytosolic iron sulfur cluster assembly	0.2209696741675273	0.0031911159908999	0.9974538621404448	1.0	1.0	6	Q96T76,O75027,P28340	3