Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.8798628933208432 2.3959699134140764 0.0165764509056183 0.99999999993016 1.0 6 P11310 1 Heme degradation 0.8814145571868196 2.2389195544101548 0.0251611509085596 0.9999999999999996 1.0 5 P09601,P30519,P33527 3 Metabolism of porphyrins 0.7735098157960097 1.8428713976541216 0.0653477892676588 1.0 1.0 11 P09601,P30519,P08397,P33527 4 Methionine salvage pathway 0.8195352226695923 1.837919425477759 0.0660742792155417 1.0 1.0 4 Q9BV20,Q13126 2 Dna repair 0.3201940759627398 1.7387706463525718 0.0820751137827111 1.0 1.0 116 Q99627,Q9UQ84,O94782,Q96RL1,Q9HAW4,P61088,Q9NXR7,Q9BT78,P25490,Q13472,Q13535,P23025,Q13098,Q9UNS1,P20585,Q9H981,P15927,Q9BXW9,Q86WJ1,P56282,Q9NRF9,Q15554,Q92890 23 Budding and maturation of hiv virion 0.7206942736277905 1.701686408067326 0.0888141696913049 1.0 1.0 7 Q9NZZ3 1 Endosomal sorting complex required for transport escrt 0.6987961331604409 1.5825493496322194 0.1135242158045994 1.0 1.0 8 Q9NP79,Q9NZZ3,A5D8V6 3 Ikk complex recruitment mediated by rip1 0.7174446384314683 1.565099878113463 0.1175594921622877 1.0 1.0 5 P61088 1 Synthesis of leukotrienes lt and eoxins ex 0.8286369072081127 1.516083262270792 0.1294983000382861 1.0 1.0 3 P33527 1 Beta oxidation of hexanoyl coa to butanoyl coa 0.7324790039926627 1.4871694025880036 0.1369700750495002 1.0 1.0 4 Q16836 1 Beta oxidation of lauroyl coa to decanoyl coa coa 0.7324790039926627 1.4871694025880036 0.1369700750495002 1.0 1.0 4 Q16836 1 Platelet sensitization by ldl 0.6654535263379718 1.4838650435426088 0.1378447272174738 1.0 1.0 6 Q16539,Q16537 2 Beta oxidation of butanoyl coa to acetyl coa 0.8159342592514194 1.4679481558137455 0.142118306035115 1.0 1.0 3 Q16836 1 Class i mhc mediated antigen processing presentation 0.3358537172617444 1.4419854212350582 0.1493064864082556 1.0 1.0 113 O43242,P28066,O43164,P04439,Q63HN8,P61088,Q9ULT8,Q9NZ08,A0AVT1,Q9UJX3,Q14139,P20618,O75832,P28072,Q9BSL1,Q15345,Q16763,P62195,P09429,P22314,Q13867,P49721,O95352,P60900,O94979,Q9UL46,Q14997 27 Metabolism of folate and pterines 0.6612278990046137 1.4170866165377018 0.1564576049676616 1.0 1.0 8 P49914,P00374 2 Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.8003708652009551 1.4088957710044268 0.1588659902328757 1.0 1.0 3 P00374 1 Diseases of dna repair 0.6693630412133531 1.3656886493328524 0.1720367084944776 1.0 1.0 12 Q9UQ84,P20585 2 Glycogen synthesis 0.669062499999959 1.3602640371698111 0.1737463844434654 1.0 1.0 5 P46976,Q96G03,P36871,P13807 4 Interleukin 4 and interleukin 13 signaling 0.6673302329925901 1.3566875097745568 0.1748805228083401 1.0 1.0 12 P09601 1 Rhobtb3 atpase cycle 0.6671364288526862 1.3520859502268772 0.1763478213075744 1.0 1.0 5 Q15345 1 Glutathione synthesis and recycling 0.6652613358237893 1.3441235424757014 0.1789084403391196 1.0 1.0 5 Q8WUX2 1 Glycogen breakdown glycogenolysis 0.6361114492940705 1.3297318414356984 0.1836066397880316 1.0 1.0 7 P10253,Q96G03,P46976 3 Formation of fibrin clot clotting cascade 0.7783733857758179 1.32536155793925 0.185051260803986 1.0 1.0 3 P42785 1 Fanconi anemia pathway 0.6430646083434036 1.2915514902834195 0.1965125126245122 1.0 1.0 10 P15927,O94782,Q13535,Q9BXW9,Q92889 5 Mismatch repair 0.6516923706282339 1.287438419802977 0.1979415203714056 1.0 1.0 12 Q9UQ84,P15927 2 Cell extracellular matrix interactions 0.6202174627019018 1.2838343881910834 0.1991999084888056 1.0 1.0 6 Q96AC1,Q14315,P12814,Q13418 4 Cd163 mediating an anti inflammatory response 0.7620237351655204 1.263292908820917 0.2064839337089363 1.0 1.0 3 Q16539,P78536 2 Egfr downregulation 0.6256421825110995 1.2596748738042605 0.2077866730478499 1.0 1.0 8 P60953,O14964,Q14155,P42566 4 Nicotinate metabolism 0.6646524035233617 1.2108266047536074 0.2259618664622751 1.0 1.0 4 P43490 1 Glycogen metabolism 0.6113475523255153 1.1513816647849224 0.2495752535365449 1.0 1.0 10 P10253,Q96G03,P13807,P11216,P46976,Q16851,P36871 7 Keratinization 0.5895129729010857 1.147937496668897 0.2509943673902666 1.0 1.0 6 P14923,P15924 2 Formation of the cornified envelope 0.5895129729010857 1.147937496668897 0.2509943673902666 1.0 1.0 6 P14923,P15924 2 Glycogen storage diseases 0.7253530563918027 1.124501827791302 0.2608001955445584 1.0 1.0 3 P46976 1 Phenylalanine and tyrosine metabolism 0.7240698476582045 1.1196634453912866 0.2628572079230196 1.0 1.0 3 P61457 1 Vitamin b5 pantothenate metabolism 0.6074687328183979 1.0990580477800402 0.2717427472130662 1.0 1.0 5 Q13057,Q9NRN7 2 Syndecan interactions 0.6370297040596077 1.0986861208125906 0.2719049984908035 1.0 1.0 4 P12814,Q9Y296 2 Regulation of runx1 expression and activity 0.7162694783127532 1.0902891479499195 0.2755857940201278 1.0 1.0 3 Q00534 1 Smooth muscle contraction 0.5873313632839172 1.0245891449118802 0.3055570885768288 1.0 1.0 11 P04083,Q9Y490,P60660,P18206,P09493 5 Nephrin family interactions 0.5567613205823897 0.9799630341240284 0.3271043660439323 1.0 1.0 7 Q01082,Q9Y5K6,P12814,O14936,O43707 5 Nicotinamide salvaging 0.6851378478156354 0.9738768397914138 0.3301176945307409 1.0 1.0 3 P43490 1 Hdr through mmej alt nhej 0.5538276891072966 0.9671875976465046 0.3334502610420442 1.0 1.0 7 Q92878,P49916,P49959,P39748,P09874 5 Regulation of tp53 activity through methylation 0.6042156461312289 0.966750361946484 0.3336688442052811 1.0 1.0 4 Q9H9B1 1 Interaction between l1 and ankyrins 0.5998912781481821 0.9495191401900644 0.3423566420030999 1.0 1.0 4 Q12955 1 Maturation of sars cov 2 nucleoprotein 0.5422948911412372 0.9407694168755316 0.3468230367194331 1.0 1.0 6 P49841,P49840 2 Cdc6 association with the orc origin complex 0.5943980932504618 0.9276960714265458 0.3535652468933863 1.0 1.0 4 Q9UBD5 1 Hsf1 activation 0.5779591652187898 0.9246965647733408 0.355123766827071 1.0 1.0 14 P04792 1 Role of abl in robo slit signaling 0.592657544377704 0.920797502553084 0.3571561591371686 1.0 1.0 4 Q01518 1 Rho gtpase cycle 0.2987717545306457 0.9207420675820446 0.3571851074171719 1.0 1.0 153 O15498,Q07960,Q08378,Q13505,Q8NBN3,P15924,P52565,Q5VTR2,Q96JJ3,Q9BT78,P30519,Q15904,Q9H8V3,Q9NZM3,Q9Y2I1,P42166,P80723,Q13098,P60953,Q92888,Q68EM7,Q96N67,Q99707,Q9BSJ8,O14964,Q9UDY2,Q15058,Q13112,Q99832,P14923,Q13464,Q00610,Q9UQB8,O60610,Q9UNZ2,Q96KM6,O60879,Q14155,P12814,Q12792,Q16543 41 Pkmts methylate histone lysines 0.5719284812495079 0.8987789908604035 0.3687703927338863 1.0 1.0 14 Q8WTS6,Q9H7B4,Q9H9B1 3 Rna polymerase iii transcription termination 0.5324288703396187 0.8980585800920876 0.3691543195867148 1.0 1.0 6 O15160 1 Nrage signals death through jnk 0.546656461274696 0.8910322988726589 0.3729118428858036 1.0 1.0 9 Q92888,Q14155 2 Mitochondrial fatty acid beta oxidation 0.577968884920514 0.8888715161268269 0.374072135174559 1.0 1.0 16 P11310 1 Alk mutants bind tkis 0.5477264809586979 0.8502182738831169 0.395203743822109 1.0 1.0 5 Q9HC35,Q00610,Q9NR09 3 Map3k8 tpl2 dependent mapk1 3 activation 0.546671230236259 0.8459084755113274 0.3976038039919976 1.0 1.0 5 Q02750,O15111,O14920 3 Hdr through single strand annealing ssa 0.5737917593355772 0.8379736787976023 0.4020454864187237 1.0 1.0 18 Q9UQ84,P15927,Q13472,Q13535 4 Rna polymerase iii transcription initiation from type 3 promoter 0.5440582425211133 0.835253929054668 0.403574751217453 1.0 1.0 5 O15160 1 Rna polymerase iii chain elongation 0.5440582425211133 0.835253929054668 0.403574751217453 1.0 1.0 5 O15160 1 Iron uptake and transport 0.5730882311494186 0.8349939349528948 0.4037211232576272 1.0 1.0 18 P09601 1 Nucleotide biosynthesis 0.5560814123502666 0.831294347940138 0.405807366773488 1.0 1.0 14 Q06203,P31939,Q02127,P30520,P22102 5 Arms mediated activation 0.8360911645332486 0.8246550349329758 0.4095674666513984 1.0 1.0 2 P46108 1 Metalloprotease dubs 0.5200493711307882 0.8218387475871497 0.4111686777705607 1.0 1.0 7 Q9NXR7,Q96RL1 2 Methylation 0.5137735068506601 0.8181477472154904 0.4132728276403723 1.0 1.0 6 Q99707 1 Diseases of mismatch repair mmr 0.6405371642723274 0.8106351268434099 0.4175752382464543 1.0 1.0 3 P43246,P20585 2 Metabolism of cofactors 0.5373626172166999 0.808070068205243 0.4190502472272883 1.0 1.0 5 P00374 1 Nucleotide salvage 0.5137424570597198 0.7951487082491506 0.4265270039727635 1.0 1.0 7 P00813 1 P130cas linkage to mapk signaling for integrins 0.8264127380580688 0.7927894759086616 0.4279004890870759 1.0 1.0 2 P46108 1 Depolymerisation of the nuclear lamina 0.522123353979839 0.7868328440988515 0.4313797240998276 1.0 1.0 9 P14635,P02545,P42166,P50402,Q8NC56 5 Chrebp activates metabolic gene expression 0.5309780494850699 0.7823182465773687 0.4340275660983703 1.0 1.0 5 Q99943,Q13085,O00763 3 Cobalamin cbl vitamin b12 transport and metabolism 0.5302798099962245 0.7795125589455543 0.4356778424177947 1.0 1.0 5 P33527 1 Maturation of sars cov 1 nucleoprotein 0.8214174211676536 0.7764655870353335 0.4374741321486455 1.0 1.0 2 P49841 1 Pyruvate metabolism 0.5370470497251262 0.769870387195634 0.4413767814777523 1.0 1.0 13 Q04760,P53985 2 Butyrate response factor 1 brf1 binds and destabilizes mrna 0.5190048398924223 0.753122702392672 0.4513761832811593 1.0 1.0 10 Q9NPD3,Q9NPI6,Q9NQT5 3 Cell cycle checkpoints 0.283096411329035 0.7437826492544961 0.4570079786595773 1.0 1.0 150 Q04917,O43242,Q9UQ84,P28066,P31946,Q96RL1,Q9HAW4,P61088,Q9NXR7,Q7L590,O00311,Q13472,P53350,Q14566,P30154,Q9UJX3,Q13535,P20618,O75832,P28072,Q9HBM1,Q96DE5,Q8NBT2,Q16537,P15927,Q16763,P40938,P62195,Q13409,P28070,P49721,P60900,Q9UL46,Q96FJ2,O00139,Q9UBD5,Q14997,Q9Y619 38 Inlb mediated entry of listeria monocytogenes into host cell 0.495568829824505 0.7415263527531338 0.458374359403247 1.0 1.0 6 P42566 1 Platelet aggregation plug formation 0.5166580141075519 0.725233814565145 0.4683086014846296 1.0 1.0 5 P46108 1 Integrin signaling 0.5166580141075519 0.725233814565145 0.4683086014846296 1.0 1.0 5 P46108 1 Formation of incision complex in gg ner 0.5348506291704013 0.7251520951090369 0.4683587279114629 1.0 1.0 15 Q86WJ1,P61088,P15927,P23025 4 Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.5157388688542771 0.719808374945707 0.4716429877262884 1.0 1.0 11 Q9NPD3,Q9NPI6,Q9NQT5,P31946 4 Urea cycle 0.8017483609116425 0.7130830660662992 0.4757943575150525 1.0 1.0 2 P78540 1 Hiv elongation arrest and recovery 0.5296671719018182 0.7039906035650507 0.4814386253211373 1.0 1.0 15 Q9Y5B9,Q8WX92,Q8IXH7,P35269,Q14241 5 Transcriptional regulation by tp53 0.2546049631430859 0.6984477087125135 0.4848972490545806 1.0 1.0 120 Q8WX92,Q04917,Q9UQ84,O00267,P31946,Q9H9B1,Q14004,Q14241,Q8IXH7,Q13526,P35269,Q13472,P15954,P30154,Q13535,P00403,P00390,Q9NQ88,Q9NZN8,Q9NVI1,P15927,P19784,Q9BXW9,P40938,Q9Y5B9,Q16539,O95983 27 Transcriptional regulation by ventx 0.5137428912964277 0.6926586803448462 0.4885237754297264 1.0 1.0 12 Q96DE5,Q9H9B1,P04637,Q9UJX3,Q16763,Q9H1A4,Q9HCE1 7 Pexophagy 0.7945675928816711 0.6903289056603191 0.4899873741172804 1.0 1.0 2 P50542 1 Platelet homeostasis 0.5151924288227114 0.6802584785125945 0.4963408103636693 1.0 1.0 13 Q16539,Q16537,P23634 3 Repression of wnt target genes 0.5292137521051672 0.676751305754314 0.4985637581736069 1.0 1.0 4 Q13363 1 Mrna decay by 3 to 5 exoribonuclease 0.5146723346653539 0.6606038533186882 0.5088663972300551 1.0 1.0 14 Q9NPD3,Q969T7,Q9NQT5 3 Pi5p regulates tp53 acetylation 0.5972514509596941 0.6586599817797852 0.5101141361485484 1.0 1.0 3 Q13526 1 Dna damage recognition in gg ner 0.516182469226982 0.6497437218108284 0.5158577769416823 1.0 1.0 15 P25490,Q99627,Q9H981,Q13098 4 Sensory processing of sound by outer hair cells of the cochlea 0.5154237356274922 0.6467284487831046 0.5178077075746623 1.0 1.0 15 Q12965,Q01082,P35579,P15311,Q00013,P23634,Q12792,P26038 8 Dna replication initiation 0.4813401307341809 0.6403000444633739 0.5219775518514074 1.0 1.0 8 P56282,Q9NRF9 2 Interferon alpha beta signaling 0.488730794439521 0.6301208278956926 0.5286155336618634 1.0 1.0 10 Q9Y3Z3,P04439 2 Sema4d induced cell migration and growth cone collapse 0.4615089678602082 0.6031204739881366 0.5464285470812653 1.0 1.0 6 Q13464,Q7Z406,P60660 3 Pp2a mediated dephosphorylation of key metabolic factors 0.5802623360399723 0.6014625187439518 0.547531968919651 1.0 1.0 3 P30154,Q14738 2 Diseases of immune system 0.5762023735165496 0.588040059148896 0.5565054047744873 1.0 1.0 3 P09429,O15111 2 Trna modification in the nucleus and cytosol 0.4834261530001743 0.5728365782650658 0.5667553498524214 1.0 1.0 12 Q9H974,Q08J23,Q6YHU6,P07814,Q9UJA5 5 Regulation of expression of slits and robos 0.2484192204601873 0.5599254733159583 0.5755302727822653 1.0 1.0 126 P18621,O00231,Q9Y5S9,O43242,P62273,P11940,P61927,P61254,P28066,Q04637,P35268,P47914,P62857,P63220,P20618,O75832,P28072,Q8TEY7,P62195,P28070,P49721,P60900,Q9UL46,P83881,Q14997,O43347 26 Purine ribonucleoside monophosphate biosynthesis 0.4655348912326338 0.5403048909988002 0.5889867859330138 1.0 1.0 10 P31939,P30520,Q06203 3 Met activates ras signaling 0.4900231195356812 0.5367820759075327 0.5914181541478558 1.0 1.0 4 Q96S59,Q96P70 2 Aspartate and asparagine metabolism 0.4645903493676667 0.5281405299598497 0.5974018020220251 1.0 1.0 5 P08243 1 Erks are inactivated 0.4416913086001677 0.5069097867247839 0.6122181184613407 1.0 1.0 7 Q8IV63,P51452 2 Rna polymerase iii transcription initiation from type 1 promoter 0.4553416409215239 0.5023342678492942 0.61543240819192 1.0 1.0 10 O15160,Q9BUI4 2 Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4689926994369563 0.4863625826560357 0.6267101148196459 1.0 1.0 14 P49368,Q99471 2 Folding of actin by cct tric 0.4411926340857324 0.4863443657044324 0.6267230285532275 1.0 1.0 8 Q99832,P49368,P50991 3 Galactose catabolism 0.7255697783328094 0.4849432708380768 0.6277165869937171 1.0 1.0 2 Q96G03 1 Recycling of eif2 gdp 0.4326806795623104 0.4738263717834801 0.6356237271286993 1.0 1.0 7 P49770 1 Sulfur amino acid metabolism 0.4483184588099632 0.4600339414039771 0.6454918582101825 1.0 1.0 11 Q9BV20,Q13126,Q99757,Q9BV57 4 Rnd3 gtpase cycle 0.4695664785369733 0.4591041026653767 0.6461594106493167 1.0 1.0 16 Q9Y2I1 1 Regulation of bach1 activity 0.5348827573671098 0.4578160847275992 0.6470845788850255 1.0 1.0 3 Q13309 1 Rna polymerase iii transcription 0.4469153693300164 0.4550730048435125 0.6490567182436224 1.0 1.0 11 O15160,Q9BUI4 2 Rnd2 gtpase cycle 0.4633663060694792 0.4515780049241331 0.6515730182947146 1.0 1.0 15 Q07960,Q15058,Q9Y2I1 3 Vxpx cargo targeting to cilium 0.4279549736350727 0.4389699127346794 0.6606833373479142 1.0 1.0 8 O00471,Q9NV70 2 Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4463437203990009 0.4371924754893692 0.6619717662254458 1.0 1.0 12 P09601 1 Tp53 regulates transcription of genes involved in cytochrome c release 0.7059007180767989 0.4317648688971847 0.6659123152312221 1.0 1.0 2 P04637 1 Processing of dna double strand break ends 0.5090564838952197 0.430813283684808 0.666604140015427 1.0 1.0 32 Q9NXR7,Q9UQ84,P15927,Q13535,Q96RL1,Q9HAW4,P61088,Q9UNS1 8 E2f enabled inhibition of pre replication complex formation 0.4147236583314744 0.4282955820526431 0.668435935016837 1.0 1.0 6 Q9UBD5,Q9Y619 2 Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4242161749770483 0.4259470147172535 0.6701464554232042 1.0 1.0 8 Q9UJX3,Q96DE5,Q16763,Q9H1A4 4 Creatine metabolism 0.5221736414740757 0.4204463678635345 0.6741594012339289 1.0 1.0 3 Q14353,P12277 2 Trna modification in the mitochondrion 0.4099641262925334 0.4118032569020557 0.6804836340095282 1.0 1.0 6 Q969Y2 1 Rrna processing in the mitochondrion 0.4288034778657223 0.4059909198680254 0.6847492721569142 1.0 1.0 5 O15091 1 Phosphorylation of the apc c 0.4318280927707515 0.4031702355486882 0.6868229943846085 1.0 1.0 11 Q96DE5,P53350,Q9UJX4,Q9UJX3,Q16763,Q9H1A4 6 Rhou gtpase cycle 0.452678159783659 0.4015130510280955 0.6880424313433235 1.0 1.0 16 P60953,Q00610,Q9NZM3,O14964,Q14155 5 Negative regulation of met activity 0.4159697592644134 0.3978171499732115 0.690764974575786 1.0 1.0 8 O14964,P42566,Q9NWH9 3 Rho gtpases activate rocks 0.4203742460588932 0.3962512619602247 0.6919196780335091 1.0 1.0 9 Q7Z406,Q13464,O14974,P60660 4 Recognition of dna damage by pcna containing replication complex 0.459376090018948 0.3863584288642592 0.6992312333605857 1.0 1.0 19 P56282,P15927,Q9NRF9 3 Signaling by robo receptors 0.241184907615637 0.3787759643431224 0.7048542374352893 1.0 1.0 139 P18621,O00231,Q9Y5S9,O43242,P62273,P11940,P61927,P61254,O94813,P28066,Q04637,P35268,P47914,P62857,P63220,P20618,O75832,P28072,P60953,P49207,Q8TEY7,P62195,Q01518,P28070,Q9UNM6,P49721,Q8N8S7,P60900,P35080,Q9UL46,P83881,Q14997,O43347 33 Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4139546302229584 0.3750554864220987 0.7076192012664919 1.0 1.0 9 Q96DE5,P30260,Q9UJX4,Q9UJX3,Q16763,Q9H1A4 6 Post translational modification synthesis of gpi anchored proteins 0.4027036865852718 0.3703585938539321 0.7111153210537804 1.0 1.0 7 Q9ULX3 1 Atf4 activates genes in response to endoplasmic reticulum stress 0.4212559328665836 0.3684784667601268 0.7125164984388828 1.0 1.0 11 Q9NPD3,Q9NQT5 2 Prolactin receptor signaling 0.4951756938586367 0.3460211273308897 0.729326837055144 1.0 1.0 3 P63208 1 Transcriptional regulation by e2f6 0.4094737899701746 0.3457009507333351 0.7295674696879675 1.0 1.0 10 O00311,P31350,Q9H9B1 3 Regulation of hmox1 expression and activity 0.4971994174021631 0.3426710268410733 0.7318459616725184 1.0 1.0 44 P09601,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P19784,P62195,P20618,O75832,P28072,P28070 13 Maturation of sars cov 1 spike protein 0.4080826605295281 0.3418686829974288 0.7324497185194596 1.0 1.0 5 P26572,Q13724 2 Insulin processing 0.39842320928517 0.3408813559376797 0.733192900923727 1.0 1.0 8 O00471 1 Auf1 hnrnp d0 binds and destabilizes mrna 0.4939339181244023 0.3367768764783216 0.7362851057404101 1.0 1.0 42 O00231,P49721,O43242,P60900,P04792,Q9UL46,Q14997,P28066,Q04637,P62195,P20618,O75832,P28072,P28070 14 G alpha 12 13 signalling events 0.4104887929795271 0.3346875324557092 0.7378608072583699 1.0 1.0 11 Q92888 1 Rho gtpases activate cit 0.4062709710621456 0.3218966361409096 0.7475310016449193 1.0 1.0 11 O14974,P60660,Q15334,Q15058,Q7Z406 5 Tp53 regulates transcription of dna repair genes 0.4633319899634835 0.3147339330360957 0.7529636777762616 1.0 1.0 28 Q8WX92,Q9Y5B9,Q8IXH7,O00267,P35269,Q14004,Q13535,Q9BXW9,Q14241 9 Hiv infection 0.2223601606603861 0.3078613374841483 0.7581878460633129 1.0 1.0 126 Q8WX92,O43242,O00267,P28066,P04439,Q14241,Q9NZZ3,A5D8V6,Q8IXH7,P35269,O75832,P28072,Q9NP79,P62195,Q9Y5B9,P49721,P60900,Q9UL46,Q14997,O15504 20 Regulation of lipid metabolism by pparalpha 0.4457396358486588 0.304345687666225 0.7608645412078905 1.0 1.0 23 P11310 1 Signaling by interleukins 0.2515015381307544 0.2949088756183296 0.7680634915696114 1.0 1.0 111 P09601,O00231,O43242,P28066,P78417,Q8IV63,P61088,P30154,P20618,O75832,P28072,P04083,Q9H3K6,Q00169,O00170,P62195,P09429,Q13126,P28070,Q16539,P49721,P60900,P46108,Q99439,Q9UL46,P51452,Q14997 27 Sumoylation of transcription cofactors 0.3902133573629242 0.2882305441785134 0.7731702695392328 1.0 1.0 10 Q13363,Q9UIS9 2 G2 m checkpoints 0.3633933826394454 0.2826569136892635 0.7774398477054734 1.0 1.0 93 Q04917,O43242,Q9UQ84,P28066,P31946,Q96RL1,Q9HAW4,P61088,Q9NXR7,Q7L590,O00311,Q13472,Q14566,Q13535,P20618,O75832,P28072,P15927,P40938,P62195,P28070,P49721,P60900,Q9UL46,Q9UBD5,Q14997,Q9Y619 27 Rhov gtpase cycle 0.4093176840196495 0.28179467176559 0.778100956756435 1.0 1.0 15 P60953,Q96KM6,Q14155,Q00610 4 Phosphorylation of emi1 0.4627629589714583 0.2667382304812528 0.7896707163327223 1.0 1.0 3 P53350 1 Activation of bh3 only proteins 0.3854179364767188 0.2625882120941224 0.7928679866966968 1.0 1.0 11 Q96FJ2 1 Global genome nucleotide excision repair gg ner 0.4650217935108327 0.2578406671281132 0.7965298775100906 1.0 1.0 41 Q86WJ1,P56282,Q99627,Q9BT78,Q9NRF9,P25490,Q9H981,P15927,P23025,P61088,Q13098 11 Sensory processing of sound 0.4182397937393118 0.2563436957907966 0.7976854597534697 1.0 1.0 20 Q12965,Q01082,P35579,P15311,Q00013,P23634,Q12792,P26038 8 Apc c cdc20 mediated degradation of cyclin b 0.3770044152049614 0.2521057828354683 0.8009593002478972 1.0 1.0 10 Q96DE5,Q9UJX4,Q9UJX3,Q16763,Q9H1A4 5 Signaling by egfr 0.3854548730411682 0.2511871861062532 0.8016693910478496 1.0 1.0 12 P60953,P42566,O14964,Q14155,P78536 5 Apc cdc20 mediated degradation of nek2a 0.3765117976831131 0.2508128589580483 0.8019587992857133 1.0 1.0 10 Q9UJX3,Q96DE5,Q16763,Q9H1A4 4 Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3765117976831131 0.2508128589580483 0.8019587992857133 1.0 1.0 10 Q9UJX3,Q96DE5,Q16763,Q9H1A4 4 Antigen processing ubiquitination proteasome degradation 0.3734164213919875 0.2463601745845342 0.8054034323576011 1.0 1.0 89 O00231,O43242,P28066,O43164,Q9UJX4,Q63HN8,P61088,Q9ULT8,A0AVT1,P28074,Q9UJX3,Q14139,P20618,O75832,P28072,Q9BSL1,Q15345,Q99436,Q7Z6Z7,Q16763,P62195,Q9H1A4,P22314,Q13867,P28070,Q9UNM6,P49721,O95352,P60900,Q9UL46,P46934,Q14997 32 Inhibition of replication initiation of damaged dna by rb1 e2f1 0.3547723160940598 0.2433076715186254 0.8077670619225326 1.0 1.0 6 P49642 1 Translation of sars cov 1 structural proteins 0.363059597768499 0.2398064121317749 0.8104803358382875 1.0 1.0 8 P49841,P49840,Q13724,P26572 4 G1 s specific transcription 0.3740648123731009 0.2331998094984441 0.8156062537703923 1.0 1.0 11 P04818,P00374 2 Glutathione conjugation 0.3857847391901506 0.2309961146146427 0.8173178205016371 1.0 1.0 14 O43708,P14550,Q8WUX2,P78417,P48637,Q99735,P10768 7 Cargo trafficking to the periciliary membrane 0.4042222654426536 0.2300729624402515 0.8180350742043696 1.0 1.0 19 P49368,O00471,O75695,Q9NV70 4 Mapk6 mapk4 signaling 0.4578096974407225 0.2297343615822872 0.8182981922566575 1.0 1.0 48 O00231,O43242,P04792,P28066,P28074,P20618,O75832,P28072,P60953,P62195,Q9HCE1,P28070,Q9UNM6,P49721,P60900,Q9UL46,Q14997,Q16181,P25685 19 Pyruvate metabolism and citric acid tca cycle 0.437722947246736 0.229349340339395 0.8185974072690474 1.0 1.0 31 Q9H9P8,P53985,Q04760,P48735 4 Dual incision in gg ner 0.421947004164058 0.2272463444416624 0.8202321925454537 1.0 1.0 25 Q86WJ1,P56282,Q9NRF9,P15927,P23025 5 Neddylation 0.4409246349977881 0.2254606661245057 0.821620921516204 1.0 1.0 66 O00231,Q99627,O43242,P28066,Q9BT78,P20618,O75832,P28072,Q9H0A8,Q13098,Q15345,P61962,P62195,P28070,P49721,P60900,Q9UL46,Q14997,O75147 19 Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.6137995629097667 0.2250974939256576 0.8219034305163395 1.0 1.0 2 O00767 1 Tp53 regulates transcription of death receptors and ligands 0.6137995629097664 0.2250974939256576 0.8219034305163395 1.0 1.0 2 P04637 1 Sema4d in semaphorin signaling 0.3563782062859767 0.2229713898317009 0.8235577735871444 1.0 1.0 8 Q13464,Q9NWH9,P60660,Q7Z406,P35579 5 Metabolism of polyamines 0.4474310774397743 0.2205699172923899 0.8254273266803964 1.0 1.0 39 Q9UNM6,O00231,P49721,O43242,P60900,P52788,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 15 Cell death signalling via nrage nrif and nade 0.3814071255090344 0.2204389332311202 0.8255293267190251 1.0 1.0 14 Q92888,Q14155,P42575,Q9H8V3 4 Regulation of mrna stability by proteins that bind au rich elements 0.4452130970288099 0.2198109679278915 0.8260183773627896 1.0 1.0 62 O00231,O43242,P04792,P28066,P31946,Q04637,Q9NQT5,Q9NPI6,P20618,O75832,P28072,Q01105,Q9NPD3,P62195,P28070,Q16539,P49721,P60900,Q9UL46,Q92973,Q14997 21 G2 m dna damage checkpoint 0.4469956481061696 0.2195774462994216 0.8262002579891883 1.0 1.0 39 Q04917,Q9NXR7,Q9UQ84,P15927,Q13535,Q96RL1,P61088 7 Pentose phosphate pathway 0.3547485258357127 0.2189802246467329 0.8266654523746035 1.0 1.0 8 O95336,Q96G03,P29401,P60891 4 Activation of nima kinases nek9 nek6 nek7 0.3596045208707292 0.2151463208832624 0.8296532405561914 1.0 1.0 5 P53350 1 Metabolism of water soluble vitamins and cofactors 0.4422109029791229 0.2148675770325299 0.8298705642486879 1.0 1.0 37 P43490,P00374,Q9H2D1,O00764,P49914,P33527,Q13057 7 Hiv transcription elongation 0.397483784449633 0.2142742998849085 0.8303331583250708 1.0 1.0 19 Q8WX92,Q9Y5B9,Q8IXH7,P35269,Q14241 5 Activated tak1 mediates p38 mapk activation 0.3744573706691324 0.2129364924877039 0.8313764981591514 1.0 1.0 4 P61088 1 Rhobtb1 gtpase cycle 0.3959271372536844 0.2107332702491204 0.8330954116303024 1.0 1.0 19 Q7Z6E9,Q9UM54,Q13464,P38159,Q9BT78,Q13618,P62995,P61201,Q99832,Q13098,Q5VTR2 11 Cdt1 association with the cdc6 orc origin complex 0.4426976892428684 0.2050681216050109 0.8375189024004619 1.0 1.0 41 Q9UNM6,O00231,P49721,O43242,P60900,Q9UBD5,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,Q9Y619,P28070 16 Defects in cobalamin b12 metabolism 0.3701338720408392 0.2042416462443756 0.8381646682102146 1.0 1.0 4 P22033,Q99707 2 Processive synthesis on the c strand of the telomere 0.3678650187867534 0.1986213365892069 0.8425589619542733 1.0 1.0 13 P15927 1 Synthesis of pips at the plasma membrane 0.3360425132854072 0.1971048252675781 0.8437455074844027 1.0 1.0 6 Q9BTU6,Q01968,P61106,O00443,P20339 5 Gap filling dna repair synthesis and ligation in gg ner 0.3895384110345352 0.1966306968476987 0.844116546935334 1.0 1.0 19 P56282,P15927 2 Degradation of axin 0.4333999163004476 0.1958674546209047 0.8447139112809281 1.0 1.0 37 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Cross presentation of soluble exogenous antigens endosomes 0.4333999163004476 0.1958674546209047 0.8447139112809281 1.0 1.0 37 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Adaptive immune system 0.2422790382698917 0.1954668993479928 0.8450274483468234 1.0 1.0 182 O43242,P28066,P31946,O43164,P04439,Q63HN8,P61088,Q9ULT8,Q9NZ08,A0AVT1,P30154,Q14139,Q9UJX3,P20618,O75832,P28072,Q9BSL1,Q15345,Q16537,P53680,Q16763,P62195,P09429,P22314,Q13409,Q13867,P28070,P61163,P49721,O95352,P60900,Q8N8S7,O94979,Q9UJW0,Q9UL46,Q96FJ2,O00139,Q14997 38 Regulation of pyruvate dehydrogenase pdh complex 0.3383315820041855 0.1915058192500706 0.8481293218119339 1.0 1.0 7 O43708,P11177,Q8NCN5,P08559 4 Myogenesis 0.3334859880776818 0.1912741708715973 0.8483107961384568 1.0 1.0 6 P60953,Q16539 2 Homologous dna pairing and strand exchange 0.3864045270763244 0.1899671276092832 0.8493348898087871 1.0 1.0 19 Q9UQ84,P15927,Q13535 3 Stabilization of p53 0.4327632346876472 0.1890362375426292 0.8500644153345174 1.0 1.0 39 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P04637,P62195,P20618,O75832,P28072,P28070 15 Asymmetric localization of pcp proteins 0.4296476892747513 0.1853939225774301 0.8529200748777197 1.0 1.0 38 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Rho gtpases activate paks 0.3574802131525052 0.1849991748192496 0.8532296828012831 1.0 1.0 12 P60953,O14974,P60660,P35240,Q7Z406,P35579 6 Tp53 regulates transcription of caspase activators and caspases 0.4221861140848146 0.1849885808380056 0.8532379921672855 1.0 1.0 3 P42575 1 Translesion synthesis by polh 0.3567647954654229 0.1834822052720511 0.8544196798946828 1.0 1.0 12 P35249,P15927,P40938,P27694,Q92890,Q8TAT6 6 Antigen presentation folding assembly and peptide loading of class i mhc 0.3721318844941568 0.1826254649746788 0.8550919022020076 1.0 1.0 16 Q9NZ08,P04439 2 Metabolism of rna 0.1772464621140966 0.1749877782102503 0.8610892369886669 1.0 1.0 451 Q9Y5S9,Q9NXG2,Q9ULX3,Q9H974,O15091,P62273,O43242,P04792,O75494,O00267,P61254,P28066,Q16637,P61927,Q05519,P31946,Q04637,Q969T7,P47914,O60231,O00566,Q8WUA2,Q9NQT5,P62857,P35269,Q9NPF4,Q13769,P63220,Q9BV38,Q9NPI6,Q9UJA5,O75937,P09234,O75832,P28072,O43818,Q01105,Q9NPD3,P33240,Q08J23,Q92733,Q9NZN8,Q6YHU6,Q10570,Q92917,Q9H2H8,P62195,Q6PGP7,Q9UBB9,Q7L014,Q16539,P49721,P60900,Q9UL46,P62314,P83881,P07814,Q969Y2,P82979,Q14997,Q8N1F7,O15504 62 Degradation of dvl 0.4189652700340024 0.165230525695544 0.8687625394373351 1.0 1.0 38 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 E2f mediated regulation of dna replication 0.3477629716071229 0.1651572487475648 0.86882021365317 1.0 1.0 12 Q9UBD5,P30154,Q9Y619,P49642 4 Oncogene induced senescence 0.3208523541573219 0.1641786775618027 0.8695904861725976 1.0 1.0 6 Q00534,Q9HCE1 2 Ikba variant leads to eda id 0.5760224789260006 0.1636054761731903 0.8700417334364374 1.0 1.0 2 O15111 1 Nf kb is activated and signals survival 0.5760224789260007 0.1636054761731903 0.8700417334364374 1.0 1.0 2 Q13501 1 P75ntr recruits signalling complexes 0.5760224789260007 0.1636054761731903 0.8700417334364374 1.0 1.0 2 Q13501 1 P75ntr signals via nf kb 0.5760224789260007 0.1636054761731903 0.8700417334364374 1.0 1.0 2 Q13501 1 Regulation of ras by gaps 0.4179541028281296 0.1611627192019286 0.8719652430004472 1.0 1.0 39 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Regulation of runx3 expression and activity 0.4137340701327279 0.1610955434637707 0.8720181502034232 1.0 1.0 36 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,P28066,P28074,P62195,P20618,O75832,P28072,P28070 13 Mastl facilitates mitotic progression 0.3456133391405565 0.1602463864206724 0.8726869904130463 1.0 1.0 4 P30154 1 Pcna dependent long patch base excision repair 0.3702661222047794 0.1583170115625119 0.8742070039019969 1.0 1.0 19 P56282,P15927 2 Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3392611572514816 0.1567592348798238 0.8754346014175138 1.0 1.0 11 P27348,O14757,Q04917,P14635,P61981,P31946 6 Perk regulates gene expression 0.3505151510465686 0.1552461424192718 0.8766272728335227 1.0 1.0 14 Q9NPD3,Q9NQT5 2 Uptake and function of anthrax toxins 0.5691539182016797 0.1539631648965398 0.8776387793774363 1.0 1.0 2 Q02750 1 Attachment of gpi anchor to upar 0.3412804332136427 0.1534135432191737 0.8780721653671779 1.0 1.0 4 O43292 1 Infectious disease 0.1757946124897466 0.1511353214364223 0.8798689700362765 1.0 1.0 347 Q8WX92,P09601,O43242,P62273,O00267,P61927,P61254,P28066,O00410,P04439,P19525,Q63HN8,P35268,Q14241,P47914,P49841,Q9NZZ3,A5D8V6,O00505,P26572,Q92747,Q8IXH7,Q96JJ3,Q13217,P62857,P35269,P63220,P20618,O75832,P28072,P49840,P78536,P61160,Q9NP79,O14964,P62195,Q14457,O15144,Q13409,Q9Y5B9,Q16539,P49721,P60900,P46108,O95983,Q9UQB8,Q9UL46,Q96FJ2,P83881,P42566,Q13263,Q14997,Q8N1F7,O15504 54 Hdr through homologous recombination hrr 0.3912175231238713 0.1496528267311528 0.8810385277436905 1.0 1.0 28 Q9UQ84,P56282,P15927,Q9NRF9 4 Rhof gtpase cycle 0.3569788911078549 0.1469587800583292 0.8831645557402827 1.0 1.0 17 Q07960,Q9BSJ8,O60610,O60879,P42166,P80723 6 Cellular responses to stimuli 0.231357738069416 0.1461966876618634 0.8837661203302758 1.0 1.0 325 P48723,P09601,O43242,P62273,P04792,P61927,P61254,P28066,P49748,Q9H9B1,P35268,P49841,P47914,O43909,Q99543,Q13217,Q9NQT5,P62857,P30519,Q9Y490,P63220,P15954,Q9UJX3,Q13535,P00403,P20618,O75832,P28072,P21281,P00390,P34932,P49840,Q9NPD3,Q96DE5,Q0VDF9,P08243,P15927,Q9Y5K8,P19784,Q16763,P33527,P62195,Q13409,Q99757,P28070,Q00534,P49721,Q16539,P60900,O94979,Q9UJW0,P30043,Q96FJ2,Q9UL46,P83881,Q9NWM8,Q14997,Q15554,Q8N1F7,O15504 60 Muscle contraction 0.384688884768092 0.1429405865476915 0.886337104244886 1.0 1.0 27 Q12797,P04083,Q9Y490,P60660,P18206,P09493,P23634 7 Rna polymerase ii transcription 0.1886668212796015 0.1428999607332844 0.8863691895850263 1.0 1.0 311 Q8WX92,Q04917,Q9Y5S9,O43242,Q9UQ84,O00267,P28066,Q05519,Q9H9B1,Q14004,P31946,Q9UBL3,P42858,Q14241,P49841,Q8IXH7,O00311,Q9BY77,Q13526,P35269,P25490,Q13472,Q13769,P15954,Q9UJX3,P30154,Q13535,O15047,P00403,P20618,O75832,P28072,P00390,P33240,Q96DE5,Q7KZ85,Q9NQ88,Q9NZN8,Q10570,Q9NVI1,P15927,Q8N201,P19784,Q9BXW9,P62195,Q16763,P40938,P28070,P31350,Q9Y5B9,Q00534,P49721,Q16539,P42575,P60900,O95983,Q9UL46,Q13263,Q8WYQ5,P82979,Q12824,Q14997,Q9UHY1 63 Signaling by rho gtpases miro gtpases and rhobtb3 0.2523816213774723 0.1425230829485273 0.8866668479220972 1.0 1.0 251 Q04917,O14974,O15498,Q07960,Q08378,Q13505,P31946,P60660,Q8NBN3,P15924,P52565,Q5VTR2,Q92747,Q96JJ3,Q9BT78,Q13526,P30519,Q9Y6G9,Q15904,P53350,Q15334,P30154,Q9Y2I1,Q9H8V3,P42166,P80723,Q9NZM3,Q13098,P61160,Q15345,Q92888,Q68EM7,P60953,Q9HBM1,Q8NBT2,Q96N67,Q99707,Q9BSJ8,Q16537,O14964,Q9UDY2,Q15058,Q13112,Q99832,P52306,P14923,O15144,Q13409,Q16539,Q13464,Q00610,Q9UQB8,P35080,Q96FJ2,O60610,Q96KM6,Q9UNZ2,O00139,O60879,Q14155,Q7Z406,P12814,Q12792,Q16543,P35579 65 Cell cycle 0.2261327511731937 0.1416639930303419 0.8873454174348849 1.0 1.0 305 Q68CZ6,Q04917,O14974,O43242,Q8N1F7,Q9UQ84,P28066,P31946,Q9BPX3,Q96RL1,Q9HAW4,P61088,P49841,P04183,Q9NXR7,Q7L590,O60763,O00311,Q96CW5,P49642,Q9UH99,Q13472,P04818,P00374,O60216,Q14566,P30154,P53350,Q9UJX3,P42166,Q13535,P20618,O75832,P28072,Q01105,Q9HBM1,Q96DE5,Q8NBT2,Q16537,P15927,P19784,Q16763,P40938,P62195,Q9H6D7,Q13409,P28070,P31350,Q9UIS9,P56282,P61163,P49721,Q00534,P60900,Q9NRF9,Q9UL46,Q96FJ2,Q15154,P53990,Q92973,Q15554,O00139,Q9HC35,Q9UBD5,Q14997,Q9Y619,Q86XI2,O15504 68 Formation of tc ner pre incision complex 0.3690358273857735 0.1398137989773437 0.8888071103811923 1.0 1.0 22 Q99627,Q9BT78,P23193,Q93009,P23025,Q9UNP9,Q13098 7 Diseases of signal transduction by growth factor receptors and second messengers 0.2008787301955257 0.1381393448273533 0.8901302911622413 1.0 1.0 148 O00231,O43242,P28066,P31946,P31939,Q13501,Q63HN8,P49841,Q99956,Q9NR09,Q8IWJ2,P35269,Q6WCQ1,Q9Y490,P30154,Q96PU8,P20618,O75832,P28072,P49840,P78536,P49815,Q16537,Q86WB0,P18206,P49589,P62195,P28070,Q9UNM6,P49721,O95352,Q13363,Q00610,P62753,P60900,O94979,Q9UL46,Q9HC35,P02545,Q14789,Q16543,Q14997,P35579 43 Cellular response to chemical stress 0.3747429015611906 0.1378131350427358 0.8903881031545013 1.0 1.0 76 P09601,O43242,P28066,P30519,P15954,P00403,P20618,O75832,P00390,P28072,P19784,P62195,P33527,P28070,Q99757,P49721,P60900,Q9UL46,P30043,Q14997 20 Gap junction degradation 0.319062500000012 0.1376678653758447 0.8905029172443977 1.0 1.0 5 Q9UM54,P09496,Q00610,Q96CW1 4 Dectin 1 mediated noncanonical nf kb signaling 0.4065866046444427 0.137651925814526 0.8905155152394204 1.0 1.0 42 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Tnfr2 non canonical nf kb pathway 0.4065866046444427 0.137651925814526 0.8905155152394204 1.0 1.0 42 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Dna damage reversal 0.3187953303018207 0.1372469455148129 0.8908356048181687 1.0 1.0 5 Q6P6C2,Q8N3C0 2 Innate immune system 0.1928219133086532 0.1365072720090877 0.8914202761327363 1.0 1.0 283 P09601,P42785,P28066,P04439,Q8IV63,O00264,P61088,P15924,P81605,P30519,O75787,P28072,P68402,P46976,Q9BUI4,O15160,O15144,P49721,O95352,P60900,P46108,Q9UQB8,P53990,O00764,P31949,P36871,Q14997 27 Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.3287836165612836 0.1352717260885598 0.8923970388943667 1.0 1.0 4 P30154,Q14738 2 Dna damage bypass 0.3739635552466288 0.1341933229104596 0.8932497057033724 1.0 1.0 25 P56282,P15927,O94782,Q9NRF9 4 Rho gtpase effectors 0.1981647457454901 0.1332822070762988 0.8939701987453865 1.0 1.0 113 Q04917,O14974,P31946,P60660,Q92747,Q13526,P53350,P30154,Q9HBM1,Q8NBT2,Q16537,Q15058,Q13409,O15144,Q16539,Q9UQB8,P35080,Q96FJ2,O00139,O60879,Q7Z406 21 Cristae formation 0.3547983512361089 0.1321584044265683 0.8948590009265591 1.0 1.0 19 Q13505 1 Developmental biology 0.1601347177393953 0.1317049451253798 0.8952176739507243 1.0 1.0 262 Q14966,P61254,Q04637,P35268,P49841,Q92747,Q9Y490,P20618,P61160,P53680,P14923,O15144,P28070,P49721,Q00610,Q9Y2W1,Q14155,Q7Z406,P18621,O00231,P62273,P11940,O94813,Q9NR77,P15924,Q9NVC6,P62857,P25490,Q15334,P28072,P60953,P49207,Q8TEY7,Q9UNM6,Q13464,P62753,P60900,P83881,Q14997,P35579,O43347,Q9Y5S9,Q01082,Q14574,Q96P70,P28066,P62277,P47914,Q96S59,O60244,P15311,P63220,P28074,Q99436,Q12955,O75448,O60271,P18077,O15143,P35080,Q14185,P62847,O43242,Q9NWH9,P61927,P60660,Q9UBL3,P26038,P35241,P38919,P46778,P46779,Q07020,O75832,Q00169,P19784,P62195,Q01518,Q16539,Q8N8S7,Q9UL46 81 Degradation of gli1 by the proteasome 0.4014978112167534 0.1316294957836873 0.8952773542504886 1.0 1.0 41 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Clec7a dectin 1 induces nfat activation 0.551358101779575 0.1311549473385737 0.89565273483007 1.0 1.0 2 O43865 1 Cytoprotection by hmox1 0.3921034702520927 0.1307457190158886 0.8959764642010726 1.0 1.0 66 P09601,P62195,P33527,P49721,O43242,P60900,Q9UL46,P30519,P30043,P28066,Q14997,P15954,P19784,P00403,P20618,O75832,P28072,P28070 18 Cell cycle mitotic 0.1996078561870045 0.1306477147941496 0.8960539952422717 1.0 1.0 257 Q68CZ6,O14974,O43242,Q8N1F7,P28066,Q9BPX3,P49841,P04183,Q7L590,O60763,O00311,Q96CW5,P49642,P04818,P00374,O60216,Q14566,P30154,P53350,Q9UJX3,P42166,P20618,O75832,P28072,Q01105,Q9HBM1,Q96DE5,Q8NBT2,Q16537,P15927,P19784,Q16763,P40938,P62195,Q9H6D7,Q13409,Q9UIS9,P28070,P31350,P56282,P61163,P49721,Q00534,P60900,Q9NRF9,Q9UL46,Q96FJ2,Q15154,P53990,Q92973,Q9HC35,O00139,Q9UBD5,Q14997,Q9Y619,Q86XI2,O15504 57 Rnd1 gtpase cycle 0.3320736216388262 0.1301385660340784 0.8964567982728224 1.0 1.0 13 P15924 1 Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.3156736370616293 0.1299046695409953 0.8966418498376085 1.0 1.0 9 A0AVT1,P45974,Q93009,Q16763,P22314 5 Signaling by alk in cancer 0.3882624066177391 0.1287859100326099 0.897527054843051 1.0 1.0 33 P62753,Q9NR09,Q00610,Q8IWJ2,O94979,Q86WB0,P31939,P18206,Q9HC35,Q13501,Q63HN8,P49589 12 Cytokine signaling in immune system 0.2100171141532529 0.128680971340128 0.8976100928813886 1.0 1.0 176 P09601,O43242,P78344,P28066,Q04637,P04439,P19525,Q8IV63,P61088,O00505,O43432,Q13526,P30154,P20618,O75832,P28072,P78536,P04083,P61221,Q9Y3Z3,Q9H3K6,Q00169,O00170,P62195,P09429,Q13126,Q16539,P49721,P60900,P46108,Q99439,Q9UL46,P29372,P51452,Q14997,Q8N1F7,O15504 37 Mitotic metaphase and anaphase 0.1876960969734403 0.1284454365157957 0.8977964757838266 1.0 1.0 135 O00231,O43242,P28066,Q9UJX4,Q8NC56,P14635,Q9Y6G9,O60216,P53350,P30154,P28074,Q86Y07,P42166,Q9UJX3,P20618,O75832,P28072,Q9HBM1,Q96DE5,Q8NBT2,Q16537,Q16763,P62195,Q9H1A4,Q13409,P28070,Q9UNM6,P49721,P60900,Q9UL46,Q96FJ2,P53990,Q92973,P02545,O00139,Q14997,Q8N1F7 37 Signaling by wnt in cancer 0.3182128245740087 0.1271904697877304 0.8987896481278719 1.0 1.0 10 P49841,Q13363,Q16537 3 Apoptotic cleavage of cell adhesion proteins 0.3000349009212854 0.125824997286709 0.8998704540541933 1.0 1.0 6 P15924 1 Homology directed repair 0.4011972450321009 0.1257955599142346 0.8998937565290954 1.0 1.0 47 Q9NXR7,P56282,Q9UQ84,Q9NRF9,Q13472,P15927,Q13535,Q96RL1,Q9HAW4,P61088,Q9UNS1 11 Hedgehog on state 0.3969150231756927 0.1253186558459879 0.9002712833822086 1.0 1.0 41 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P48729,P28070 15 Acyl chain remodeling of cl 0.382261086820733 0.1247835561013552 0.9006949059608664 1.0 1.0 3 P40939,Q6UWP7 2 Termination of translesion dna synthesis 0.3499211778049277 0.1247455428106793 0.9007250010318636 1.0 1.0 19 P56282,P15927 2 Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.3559130993994424 0.12430995590294 0.9010698647759368 1.0 1.0 21 P56282,P15927 2 Association of tric cct with target proteins during biosynthesis 0.3418948491111487 0.1227606171619389 0.9022966612590622 1.0 1.0 17 P61962,P49368,Q15477,Q99832,P51784 5 Nervous system development 0.1860509880997886 0.1216412988303617 0.9031831045956396 1.0 1.0 217 P18621,O00231,Q9Y5S9,P35579,Q01082,O43242,P62273,Q9NWH9,P11940,Q96P70,P61254,O94813,Q9NR77,P28066,Q04637,P61927,P60660,P62277,P35268,P49841,P47914,P26038,P35241,P38919,Q96S59,Q92747,P46778,P46779,P15311,P62857,Q9Y490,P63220,Q07020,Q15334,P28074,P20618,O75832,P28072,P61160,P60953,Q99436,P49207,Q12955,Q8TEY7,Q00169,P19784,P53680,P62195,Q01518,O15144,P18077,P28070,O15143,Q9UNM6,P49721,Q13464,Q8N8S7,Q00610,P62753,P60900,P35080,Q14185,Q16539,Q9UL46,P83881,P62847,Q14155,Q7Z406,Q14997,O43347 70 Darpp 32 events 0.3014383989993736 0.1208760391648578 0.9037892209667526 1.0 1.0 7 P13861,P30153,P10644,Q14738,P30154,P62136 6 Metabolism of amino acids and derivatives 0.2045698736991355 0.1208443829190357 0.9038142951941444 1.0 1.0 196 O43242,P62273,P61927,P61254,Q9NR77,P54687,P28066,P23378,P47914,P62857,P63220,Q9BV20,P52788,P28072,O75832,Q9BV57,P52758,Q99707,P08559,Q02252,P08243,P62195,Q13126,Q99757,P49721,P78540,P60900,Q96I15,Q9UL46,P83881,P07814,Q14997 32 G1 s dna damage checkpoints 0.3933348914037989 0.1206335426697289 0.9039812996395726 1.0 1.0 41 Q9UNM6,O00231,P49721,Q99436,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P04637,P62195,P20618,O75832,P28072,P28070 16 M phase 0.1956139068120334 0.1181361923468253 0.9059597468836352 1.0 1.0 192 Q68CZ6,O00231,O43242,Q8N1F7,P28066,Q9H8Y8,Q9UJX4,Q9BPX3,Q8NC56,O60763,Q96CW5,P14635,Q9Y6G9,O60216,P53350,P30154,P28074,Q86Y07,P42166,Q9UJX3,P20618,O75832,P28072,Q01105,Q9HBM1,Q96DE5,P62820,Q99436,Q8NBT2,Q16537,P19784,Q16763,P62195,Q9H6D7,Q9H1A4,Q13409,Q9UIS9,P28070,Q9UNM6,P61163,P49721,P60900,Q9UL46,Q96FJ2,Q15154,P53990,Q14204,Q92973,Q9HC35,P02545,O00139,P49790,P35658,Q9BW27,Q99567,Q14997,Q86XI2,O15504 58 Nod1 2 signaling pathway 0.3031710797092867 0.116827274014209 0.9069969302048656 1.0 1.0 8 Q16539,P61088 2 Mitotic g1 phase and g1 s transition 0.3464775286290361 0.1160580669450477 0.9076065218990363 1.0 1.0 80 O43242,P28066,P04183,Q7L590,O00311,P49642,P04818,P00374,Q14566,P30154,P20618,O75832,P28072,P15927,P62195,P28070,P31350,P56282,P49721,Q00534,P60900,Q9NRF9,Q9UL46,Q9UBD5,Q9Y619 25 Transcriptional regulation by runx3 0.3887621225514387 0.1149556610462779 0.9084802663394866 1.0 1.0 41 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,P28066,P28074,P04637,P62195,P20618,O75832,P28072,P28070 14 Regulation of runx2 expression and activity 0.3879599107769759 0.1112850350409204 0.911390321998357 1.0 1.0 44 Q9UNM6,O00231,P49721,Q99436,O43242,P60900,P28072,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P49841,P28070 16 Rrna processing 0.1698289748424465 0.1102992836618163 0.9121720253539276 1.0 1.0 163 O00566,Q9NPD3,Q9NXG2,Q9ULX3,P62273,Q9NQT5,P62857,P61254,P83881,Q9BV38,P47914 11 Switching of origins to a post replicative state 0.3817531949396333 0.1075325676835234 0.9143664898297996 1.0 1.0 59 O00231,O43242,P28066,Q9UJX4,Q14566,P28074,Q9UJX3,P20618,O75832,P28072,Q96DE5,Q16763,P62195,Q9H1A4,P28070,Q9UNM6,P49721,P60900,Q9UL46,Q9UBD5,Q14997,Q9Y619 22 Transcription of the hiv genome 0.3462807751320105 0.1073333831302156 0.9145245015995158 1.0 1.0 22 Q8WX92,Q9Y5B9,Q8IXH7,P35269,Q14241 5 Degradation of beta catenin by the destruction complex 0.3846143708655419 0.1058885347843058 0.9156707908404708 1.0 1.0 51 O00231,O43242,P28066,Q04726,P49841,P48729,P28074,P30154,P20618,O75832,P28072,Q16537,P62195,P28070,Q9UNM6,P49721,Q13363,P60900,Q9UL46,Q14997 20 Regulation of pten localization 0.3651869616180775 0.1050728342966883 0.9163180150493664 1.0 1.0 3 Q93009 1 Insulin receptor recycling 0.302730683411523 0.1043170615448467 0.9169177386274984 1.0 1.0 10 Q15904,P21281,Q9Y5K8,P38606 4 Erk mapk targets 0.3020368574155698 0.1033869651968429 0.9176558569734734 1.0 1.0 10 Q16539,Q8IV63,P51452 3 Mapk targets nuclear events mediated by map kinases 0.3020368574155698 0.1033869651968429 0.9176558569734734 1.0 1.0 10 Q16539,Q8IV63,P51452 3 Rac1 gtpase cycle 0.3792188540407383 0.1019260854575923 0.9188153445853752 1.0 1.0 44 P60953,Q68EM7,Q96N67,O15498,Q8IZP0,Q9UQB8,Q07960,Q9BSJ8,Q14185,Q9H8V3,Q9Y2I1,Q86Y07,P42166,Q13112,Q16513,Q14155,P52565 17 Detoxification of reactive oxygen species 0.3005290358632674 0.1013932361798087 0.9192383055512828 1.0 1.0 10 P00390,Q99757 2 Prevention of phagosomal lysosomal fusion 0.2993292495067309 0.1013620174460836 0.9192630868253556 1.0 1.0 4 Q9H267,O14964 2 Cdc42 gtpase cycle 0.3648175830622591 0.0999040552891247 0.9204204968060344 1.0 1.0 33 Q68EM7,Q96N67,O15498,Q9UQB8,Q07960,Q9H8V3,Q14155,P42166,P14923,P52565 10 Dna replication 0.2815023815137378 0.0988851987020391 0.921229421027298 1.0 1.0 92 O00231,O43242,P28066,Q9UJX4,Q7L590,O00311,P49642,P28340,Q14566,P28074,Q9UJX3,P20618,O75832,P28072,Q96DE5,P15927,Q16763,P40938,P62195,Q9H1A4,P28070,P56282,P49721,Q9UNM6,P60900,Q9NRF9,Q9UL46,O60684,P18858,Q9UBD5,Q14997,Q9Y619 32 Nucleotide excision repair 0.3767298396809019 0.0982962378376093 0.9216970654869174 1.0 1.0 51 Q86WJ1,P56282,Q99627,Q9BT78,Q9NRF9,P25490,Q9H981,P15927,P23025,P61088,Q13098 11 Orc1 removal from chromatin 0.3763990522203808 0.0979983595950831 0.9219335959525689 1.0 1.0 51 P49721,O43242,P60900,Q9UBD5,Q9UL46,Q14997,P28066,Q14566,P62195,P20618,O75832,P28072,Q9Y619,P28070 14 Formation of rna pol ii elongation complex 0.3450403296003888 0.0966200348504268 0.9230281454246688 1.0 1.0 25 Q8WX92,Q9Y5B9,Q8IXH7,P35269,Q7KZ85,Q14241 6 Regulation of tp53 activity through phosphorylation 0.3596108725631515 0.0963202427503142 0.923266234444014 1.0 1.0 32 Q9Y5B9,Q9UQ84,Q13526,Q13472,P15927,P19784,Q13535 7 Activation of bad and translocation to mitochondria 0.2884824475729755 0.0962984145874231 0.9232835702126057 1.0 1.0 8 Q04917 1 Listeria monocytogenes entry into host cells 0.2884575117312897 0.0962666639039179 0.9233087864401252 1.0 1.0 8 P42566 1 P75 ntr receptor mediated signalling 0.3339631101027238 0.096210703736125 0.9233532299016276 1.0 1.0 21 Q92888,P42575,Q9NQC3,Q9H8V3,Q14155,P52565,P78536 7 Rab gefs exchange gtp for gdp on rabs 0.3506169984112097 0.0951643480895183 0.9241842875327636 1.0 1.0 28 O95248,O43617,Q9Y296,Q5VZ89 4 Hedgehog ligand biogenesis 0.3704417883360219 0.0947735341042506 0.9244947089537828 1.0 1.0 42 Q9UNM6,O00231,P49721,O43242,P60900,P28070,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P78536 15 Separation of sister chromatids 0.2009112251045575 0.094706201488462 0.9245481920463924 1.0 1.0 105 O43242,P28066,O60216,P53350,P30154,Q9UJX3,P20618,O75832,P28072,Q9HBM1,Q96DE5,Q8NBT2,Q16537,Q16763,P62195,Q13409,P49721,P60900,Q9UL46,Q96FJ2,O00139,Q14997 22 Regulation of pten stability and activity 0.369832869228605 0.093151889919989 0.9257828944115098 1.0 1.0 44 Q9UNM6,O00231,P49721,Q99436,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P19784,P46934,P62195,P20618,O75832,P28072,P28070 17 Negative regulation of notch4 signaling 0.3651980205246484 0.091545448501069 0.9270591951380556 1.0 1.0 40 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,P28066,P28074,P62195,P20618,O75832,P28072,P28070 13 Synthesis of dna 0.2970564903019905 0.0911917211036657 0.9273402531470388 1.0 1.0 85 O00231,O43242,P28066,Q9UJX4,P49642,P28340,Q14566,P28074,Q9UJX3,P20618,O75832,P28072,Q96DE5,P15927,Q16763,P40938,P62195,Q9H1A4,P28070,P56282,P49721,Q9UNM6,P60900,Q9NRF9,Q9UL46,P18858,Q9UBD5,Q14997,Q9Y619 29 Nonhomologous end joining nhej 0.3234345357214414 0.0911805359412351 0.9273491405893964 1.0 1.0 19 P61088,Q9NXR7 2 Eukaryotic translation initiation 0.1955988170058744 0.0905574691183627 0.9278442277436978 1.0 1.0 102 P18621,P62273,P11940,P61927,P61254,Q04637,Q14232,P62277,P35268,P47914,P46778,P46779,P62857,P63220,P23588,Q07020,P49770,O75822,P49207,O15372,P18077,P62753,O00303,Q15056,Q13347,O60841,P83881,P62847,O15371,P60228 30 Condensation of prometaphase chromosomes 0.2917368628809343 0.0905083858504584 0.9278832303605486 1.0 1.0 10 Q9NTJ3,P19784,Q9BPX3,P14635 4 Activation of the pre replicative complex 0.3389566403870638 0.0903455447046572 0.9280126286662144 1.0 1.0 25 P56282,Q7L590,O00311,Q9NRF9,P15927,Q9UBD5 6 Rhoj gtpase cycle 0.3334968085975631 0.0899236046501705 0.928347923341262 1.0 1.0 23 Q14155,P42166 2 S phase 0.225099511649321 0.0897673924679966 0.928472060585855 1.0 1.0 98 O43242,P28066,P49841,P49642,O60216,Q14566,Q9UJX3,P20618,O75832,P28072,Q96DE5,P15927,Q16763,P40938,P62195,P28070,P56282,P49721,P60900,Q9NRF9,Q9UL46,Q9UBD5,Q14997,Q9Y619 24 Programmed cell death 0.191075135637845 0.0894998650666098 0.9286846608156688 1.0 1.0 101 Q04917,O00231,O43242,P28066,P31946,Q15149,Q9HAW4,P15924,P20618,O75832,P28072,Q9UDY2,P62195,P09429,Q9UKG1,P28070,Q9UNM6,P49721,Q13464,P60900,Q9UL46,Q96FJ2,P02545,P04637,Q16543,Q14997 26 Cellular response to hypoxia 0.3624755655653568 0.0892191593783084 0.9289077391156332 1.0 1.0 40 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Fructose metabolism 0.3477003722809899 0.0883962129990663 0.929561771104268 1.0 1.0 3 Q3LXA3 1 Ksrp khsrp binds and destabilizes mrna 0.2972234510935722 0.0881675906465299 0.9297434758920176 1.0 1.0 12 Q9NPD3,Q9NQT5 2 Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3288569796835559 0.0879522668932116 0.929914614550253 1.0 1.0 22 P56282,P15927,Q9NRF9 3 The role of gtse1 in g2 m progression after g2 checkpoint 0.3638818232117368 0.0875913065862739 0.9302015119609676 1.0 1.0 47 Q9UNM6,O00231,P49721,O43242,P14635,P60900,Q9UL46,Q14997,P28066,P53350,P28074,P04637,P62195,P20618,O75832,P28072,P28070 17 Rac2 gtpase cycle 0.3559429261604092 0.0873249063296725 0.9304132572501288 1.0 1.0 36 P60953,Q68EM7,Q8IZP0,Q07960,Q9BSJ8,Q13505,Q14185,Q86Y07,Q13112,P42166,P52565 11 Metabolism of vitamins and cofactors 0.3630212170815469 0.0872696598992448 0.93045716987978 1.0 1.0 45 P43490,P00374,Q9H2D1,O00764,P49914,P35270,P33527,Q13057 8 Ire1alpha activates chaperones 0.3380430518974176 0.0872106512760181 0.9305040731225108 1.0 1.0 26 Q13217,O94979,Q9Y490,P49748,Q9NWM8,O43909 6 Slc transporter disorders 0.3496233272949553 0.086943155577078 0.9307166961849964 1.0 1.0 32 P53985 1 Mapk family signaling cascades 0.2490169974000822 0.0867769643386296 0.9308487983334608 1.0 1.0 92 Q01082,O00231,O43242,P07196,P04792,P28066,P31946,Q99956,Q96S59,Q9Y490,Q15334,P30154,P20618,O75832,P28072,P60953,Q16537,P18206,P62195,Q9HCE1,P28070,Q9UNM6,P49721,P60900,Q9UL46,Q14997,Q16181,P25685 28 Organelle biogenesis and maintenance 0.2471471844251216 0.0864522538816808 0.9311069097867888 1.0 1.0 92 Q16539,Q9NV70,P18085,Q6UXV4,O00471,Q13505,Q96FJ2,P49368,P53350,O75695,Q9H6D7,Q13409,Q9UIS9,P48735 14 Condensation of prophase chromosomes 0.2876637978368591 0.085885310193806 0.9315575891261578 1.0 1.0 10 Q9NTJ3,P14635,P53350,Q9UPP1,Q86XI2,Q01105 6 Mitotic g2 g2 m phases 0.2622754397067387 0.0858105329727144 0.931617033264612 1.0 1.0 89 Q68CZ6,O14974,O43242,P28066,Q96CW5,P53350,P30154,P20618,O75832,P28072,P62195,Q9H6D7,Q13409,P28070,Q9UIS9,P61163,P49721,P60900,Q9UL46,Q15154,Q14997 21 Aggrephagy 0.2978767946408193 0.0849903196455317 0.932269086667372 1.0 1.0 13 Q96FJ2 1 Runx1 regulates transcription of genes involved in differentiation of hscs 0.3566468337734038 0.0840064721357951 0.9330512859405518 1.0 1.0 41 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Apoptosis 0.2106071823259115 0.0836653395628336 0.9333225155126356 1.0 1.0 92 Q04917,O00231,O43242,P28066,P31946,Q15149,Q9HAW4,P15924,P20618,O75832,P28072,Q9UDY2,P62195,P09429,Q9UKG1,P28070,Q9UNM6,P49721,Q13464,P60900,Q9UL46,Q96FJ2,P02545,P04637,Q14997 25 Cellular response to starvation 0.1422830427786698 0.0833475730811975 0.9335751740083524 1.0 1.0 92 P62273,P62857,P61927,P61254,P83881,P63220,P08243,P47914 8 Signaling by wnt 0.2151265832509903 0.0824079906131649 0.9343222820741786 1.0 1.0 90 O43242,P28066,Q9UBL3,Q04726,P49841,O60493,P30154,P20618,O75832,P28072,Q16537,P19784,P53680,P62195,P28070,P49721,Q13363,Q00610,P60900,Q9UL46,Q9HCK8,Q14997 22 Clec7a dectin 1 signaling 0.3560418567203906 0.0821194639081677 0.9345517154372024 1.0 1.0 48 P49721,O43242,P60900,Q9UL46,O75832,Q14997,P28066,P62195,P20618,P61088,P28072,P28070 12 Hedgehog off state 0.354206394245587 0.0810658823931132 0.935389558263668 1.0 1.0 49 Q9UNM6,O00231,P49721,Q99436,O43242,P60900,P28072,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P49841,P48729,P28070 17 Regulation of hsf1 mediated heat shock response 0.3507081650153156 0.0809981827490733 0.9354433977138932 1.0 1.0 55 P48723,Q99543,P04792,P15927,O15504 5 Nonsense mediated decay nmd 0.1913792769134675 0.0802380621201528 0.9360479185426014 1.0 1.0 87 Q9Y5S9,P62273,P62857,P61254,P83881,Q9NPI6,P47914 7 Dna double strand break repair 0.3441014699487387 0.07996243161178 0.9362671354864056 1.0 1.0 59 Q9NXR7,P56282,Q9UQ84,Q9NRF9,Q13472,P15927,Q13535,Q96RL1,Q9HAW4,P61088,Q9UNS1 11 Processive synthesis on the lagging strand 0.2946529052327722 0.0783676606187042 0.9375355974797316 1.0 1.0 14 P49642,P28340,P15927,P18858,P27694 5 Inactivation of cdc42 and rac1 0.3349198283825669 0.0783000557364097 0.9375893731292876 1.0 1.0 3 O94813 1 Ub specific processing proteases 0.2873821900126952 0.0781398077411817 0.937716841983348 1.0 1.0 77 O00231,O43242,P28066,Q9HAW4,P51784,Q15388,Q9Y4E8,O60493,P20618,O75832,P28072,Q8TEY7,O14964,P62195,Q14457,P28070,P49721,P60900,Q9UL46,Q9UPU5,Q14997,Q92890 22 Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3490530924351671 0.0780531673369434 0.9377857605341896 1.0 1.0 49 O00231,O43242,P28066,Q9UJX4,P53350,P28074,Q9UJX3,P20618,O75832,P28072,Q96DE5,Q16763,P62195,Q9H1A4,P28070,Q9UNM6,P49721,P60900,Q9UL46,Q14997 20 Dna replication pre initiation 0.3229719268572679 0.07784605834107 0.9379505083275306 1.0 1.0 67 O43242,P28066,Q7L590,O00311,P49642,Q14566,P20618,O75832,P28072,P15927,P62195,P28070,P56282,P49721,P60900,Q9NRF9,Q9UL46,Q9UBD5,Q14997,Q9Y619 20 Downstream signaling events of b cell receptor bcr 0.3485628116291038 0.0778298016922878 0.9379634400222968 1.0 1.0 43 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P28072,P28070 14 Scf skp2 mediated degradation of p27 p21 0.347019501134323 0.0774360950976798 0.9382766272401226 1.0 1.0 41 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,P28066,P28074,P62195,P20618,O75832,P28072,P28070 13 Sumoylation of transcription factors 0.3332292317301644 0.0770890880640998 0.938552673631906 1.0 1.0 3 Q13330,P04637 2 Signaling by met 0.3092907512634848 0.0752478401446653 0.9400175212883322 1.0 1.0 20 Q96S59,Q96N67,P46108,P42566 4 Response of eif2ak4 gcn2 to amino acid deficiency 0.1854107143086191 0.0751882270121811 0.9400649513226964 1.0 1.0 79 P62273,P62857,P61254,P83881,P63220,P08243,P47914 7 Eukaryotic translation elongation 0.1813386087227255 0.0751854694244411 0.9400671453491228 1.0 1.0 79 P62273,P62857,P61254,P83881,P47914 5 Transcription coupled nucleotide excision repair tc ner 0.3407604281872917 0.0735275227288435 0.9413863433746958 1.0 1.0 42 P56282,Q99627,Q9BT78,Q9NRF9,P15927,P23025,Q13098 7 Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.318407397403951 0.0729013150249811 0.9418846474914812 1.0 1.0 25 P60953,Q99439,Q9UL46,P78417,Q00169,Q9H3K6,O00170,Q13126 8 Nuclear events kinase and transcription factor activation 0.2808027780575567 0.0719963657935721 0.9426048000240836 1.0 1.0 12 Q16539,Q8IV63,P51452 3 Signaling by notch4 0.3360127823282377 0.0709951046657405 0.9434016515721044 1.0 1.0 43 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,P28066,P28074,P62195,P20618,O75832,P28072,P28070 13 Transport to the golgi and subsequent modification 0.1867628674277506 0.0707907015238576 0.9435643323679674 1.0 1.0 72 O60763,P61163,P62820,O15498,Q9Y296,O94979,P35606,Q9UJW0,Q96FJ2,Q9Y6G9,Q12955,Q8IUR0,Q14789,Q13409,O43617,P26572,P18085,P24390 18 Chromatin modifying enzymes 0.2531661963317829 0.0707758866866782 0.9435761233228328 1.0 1.0 71 Q8WTS6,Q9H7B4,Q6IA86,O95983,Q9ULM3,Q9H9B1,Q9H9T3,Q9UBL3,Q12824 9 Golgi to er retrograde transport 0.1707792457719241 0.0701570449490503 0.9440686632047282 1.0 1.0 71 A2RRP1,P35606,P18085,P48444,Q9Y6G9,Q6NUQ1,P62820,P68402,Q9H2M9,Q9NP72,Q13409,P24390,P61163,Q8TD16,P84085,Q9UJW0,Q96FJ2,O00139,Q9BW19 19 Negative regulators of ddx58 ifih1 signaling 0.2603712918587341 0.0700682771548444 0.944139315787148 1.0 1.0 7 Q86UT6,Q13526 2 Transcriptional regulation by runx1 0.2894449376962056 0.0699300095308243 0.9442493674390312 1.0 1.0 66 Q00534,O00231,P49721,O43242,P60900,P20618,Q9UL46,Q14997,P28066,Q12824,P19784,O15047,P62195,Q9UBL3,O75832,P28072,Q9HCE1,P28070 18 Metabolism of nucleotides 0.3303566334762212 0.0694428469934838 0.9446371242464124 1.0 1.0 49 Q9Y3D8,P31939,P49902,Q9UKK9,Q02127,P23921,P04183,P04818,P00390,P30520,P22102,Q05682,P00813,Q9Y3Z3,Q9NRF8,P31350,Q06203,O43598,P00491 19 Signaling by vegf 0.3151864338854804 0.0693083182976453 0.9447442046180304 1.0 1.0 26 Q9UQB8,P04792 2 Pcp ce pathway 0.3305697368972887 0.0692451739677096 0.9447944657508442 1.0 1.0 48 P49721,O43242,Q00610,P60900,Q9UL46,Q14997,P28066,P53680,P62195,P20618,O75832,P28072,P28070 13 Signaling by braf and raf1 fusions 0.3106611481686206 0.0690483426439233 0.9449511394269584 1.0 1.0 24 O95352,Q6WCQ1,P31946,P18206,Q96PU8 5 Hiv life cycle 0.2215483861705189 0.0689931334689838 0.9449950851747424 1.0 1.0 69 Q8WX92,Q9Y5B9,Q8IXH7,P35269,Q14241,Q9NZZ3,A5D8V6,O15504 8 Er to golgi anterograde transport 0.2155636330170063 0.0689626278727559 0.9450193672837166 1.0 1.0 69 Q01082,O15498,Q9Y296,P35606,P18085,O60763,P48444,Q15436,Q9Y6G9,Q5JRA6,O43617,P62820,P53992,Q12955,Q13409,P24390,P61163,O94979,P84085,Q9UJW0,Q96FJ2,Q14204,Q8IUR0,Q14789 24 Tcf dependent signaling in response to wnt 0.2788717311064303 0.0688850540773406 0.9450811153760345 1.0 1.0 66 O43242,P28066,Q9UBL3,Q04726,P49841,P30154,P20618,O75832,P28072,Q16537,P19784,P62195,P28070,P49721,Q13363,P60900,Q9UL46,Q9HCK8,Q14997 19 Rhobtb gtpase cycle 0.3178802202691385 0.0686847960655025 0.9452405206029584 1.0 1.0 28 Q13464,Q13618,Q9BT78,Q12792,Q8WWQ0,P12814,Q99832,Q16543,Q13098,Q5VTR2 10 Activation of atr in response to replication stress 0.312007749260867 0.0685525875307118 0.9453457596992714 1.0 1.0 25 Q7L590,O00311,Q14566,P15927,Q13535,P40938,Q9HAW4,Q9UBD5 8 Cellular response to heat stress 0.2879673065846019 0.0684256907432667 0.9454467714975194 1.0 1.0 64 P48723,Q99543,P04792,P15927,O15504 5 E3 ubiquitin ligases ubiquitinate target proteins 0.2884664895807254 0.0678705856287904 0.945888654011589 1.0 1.0 16 P61088,P04439 2 Pten regulation 0.2388032550226781 0.0672724129366572 0.9463648384114356 1.0 1.0 66 O00231,O43242,P28066,Q93009,P28074,P20618,O75832,P28072,Q99436,P19784,P62195,Q9HCE1,P28070,Q9UNM6,P49721,P60900,O95983,Q9UL46,P04637,P46934,Q14997 21 Tcr signaling 0.3255647363358768 0.0671658119612084 0.946449701743513 1.0 1.0 47 P49721,Q8N8S7,O43242,P60900,Q9UL46,O75832,Q14997,P28066,P62195,P20618,P61088,P28072,P28070 13 Apc c mediated degradation of cell cycle proteins 0.3112059808897598 0.0670887210596397 0.946511072956268 1.0 1.0 56 O00231,O43242,P28066,Q9UJX4,P14635,P53350,P28074,Q9UJX3,P20618,O75832,P28072,Q96DE5,Q16763,P62195,Q9H1A4,P28070,Q9UNM6,P49721,P60900,Q9UL46,Q14997 21 Golgi cisternae pericentriolar stack reorganization 0.2736980854226813 0.0661819155581045 0.947232994498713 1.0 1.0 12 P53350,O60763,P62820,Q9H8Y8 4 Phase ii conjugation of compounds 0.3099793191955806 0.0661068287098889 0.9472927742219974 1.0 1.0 26 O43708,P14550,Q99707,Q8WUX2,P78417,P48637,Q99735,Q8TB61,P10768 9 Antigen processing cross presentation 0.3059214251016006 0.0644287337624719 0.9486288513166306 1.0 1.0 53 P49721,O43242,P60900,Q9UL46,Q14997,P28066,P09429,P04439,P62195,P20618,O75832,P28072,P28070 13 Cilium assembly 0.2728888316762433 0.0640377400544205 0.9489401762456356 1.0 1.0 59 P61163,P18085,P49368,O00471,Q96FJ2,Q15154,Q92973,P53350,Q9UIS9,Q9H6D7,Q13409,O75695,Q9NV70 13 Signaling by hedgehog 0.2916785329286839 0.0638997099852261 0.949050083206966 1.0 1.0 56 Q9UNM6,O00231,P49721,Q99436,O43242,P60900,P28072,P28070,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P49841,P48729,P78536 18 Interleukin 12 signaling 0.3064691683247954 0.0632029803161273 0.9496048715775642 1.0 1.0 27 P60953,Q99439,Q9UL46,P78417,Q00169,Q9H3K6,O00170,Q13126 8 Mitotic prophase 0.1682083193153596 0.0626246186605492 0.9500654250352256 1.0 1.0 59 Q8N1F7,Q9H8Y8,P50402,Q8NC56,Q9UPP1,Q9NTJ3,O60763,P14635,P53350,P30154,O95347,Q86Y07,P42166,Q01105,P62820,P20700,P49792,P02545,P49790,P35658,Q9BW27,Q99567,Q86XI2,O15504 24 Sensory perception 0.307996406714358 0.0624761750778748 0.9501836344013864 1.0 1.0 29 P23634 1 Rhob gtpase cycle 0.2933258235183525 0.0624155709680822 0.950231895296744 1.0 1.0 21 Q92888,Q13464,Q07960,O60610,Q9H8V3,Q9UDY2,P14923 7 Cyclin a cdk2 associated events at s phase entry 0.3121629780280146 0.0620368976857587 0.9505334484723152 1.0 1.0 43 Q9UNM6,O00231,P49721,O43242,P60900,Q9UL46,P28066,P28074,P62195,P20618,O75832,P28072,P28070 13 Regulation of tp53 activity 0.2949700642175064 0.0611011790071466 0.9512786301952464 1.0 1.0 50 Q9Y5B9,Q16539,O95983,Q9UQ84,Q13526,Q13472,Q9H9B1,P49959,P30154,P15927,P19784,Q13535,Q93009,P40938,P04637 15 Transcriptional regulation by runx2 0.2804449312267323 0.0610417697319559 0.951325943623323 1.0 1.0 53 Q9UNM6,O00231,P49721,Q99436,O43242,P14635,P60900,P28072,Q9UL46,Q14997,P28066,P28074,P62195,P20618,O75832,P49841,P28070 17 Meiotic recombination 0.2695890928265934 0.0609458740510331 0.9514023151139648 1.0 1.0 13 P15927 1 Trna processing 0.2585767354841817 0.0609207323202994 0.9514223381068648 1.0 1.0 55 Q9H974,Q08J23,O15091,P33240,Q6YHU6,Q10570,P07814,Q9UJA5,Q969Y2,Q8N1F7,O15504 11 Beta catenin independent wnt signaling 0.2695399633063757 0.0608395413099628 0.951486999219683 1.0 1.0 54 Q9UNM6,O00231,P49721,O43242,Q00610,P60900,Q9UL46,Q14997,P28066,P28074,P53680,P62195,P20618,O75832,P28072,Q9HCE1,P28070 17 Cytosolic trna aminoacylation 0.2942481886163844 0.0605869900169372 0.9516881349515692 1.0 1.0 23 Q9Y285,P07814,Q9NSD9,P49589 4 Mitochondrial translation 0.2292717377130508 0.0602948275318385 0.9519208214844694 1.0 1.0 55 Q15070,P82650,Q9NQ50,P09001,Q9BYD6,Q96E11,Q9BRJ2,Q13084,P82673,Q9BYC9,Q9BYD2,Q96A35,Q9BYD1,Q8TAE8 14 Unfolded protein response upr 0.3060730960725607 0.06018296215317 0.9520099153476778 1.0 1.0 42 Q9NPD3,Q13217,O94979,Q9NQT5,P49748,P08243,Q9NWM8 7 Rac3 gtpase cycle 0.3064385164266703 0.0600713278757804 0.9520988257509546 1.0 1.0 33 P60953,Q68EM7,O15498,Q8IZP0,Q9UQB8,Q07960,Q9BSJ8,Q13112,P42166 9 Dual incision in tc ner 0.3052593292192501 0.0596316284588815 0.9524490273162852 1.0 1.0 33 P56282,P15927,P23025 3 Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.2583874960062147 0.0591183285795397 0.9528578600780092 1.0 1.0 52 O00303,P62753,P62273,Q15056,P62857,P11940,O15372,Q13347,P63220,P23588,Q04637,O15371,P62277,O75822,P60228 15 Copi independent golgi to er retrograde traffic 0.2964138461930833 0.0590933499187396 0.9528777553833144 1.0 1.0 26 P61163,P68402,Q9H2M9,Q8TD16,Q9UJW0,Q96FJ2,Q9Y6G9,Q9NP72,Q13409 9 Creb1 phosphorylation through the activation of adenylate cyclase 0.3010618363522762 0.0590073193130144 0.9529462783034284 1.0 1.0 3 P13861,P10644 2 Pka activation in glucagon signalling 0.3010618363522762 0.0590073193130144 0.9529462783034284 1.0 1.0 3 P13861,P10644 2 Pka mediated phosphorylation of creb 0.3010618363522762 0.0590073193130144 0.9529462783034284 1.0 1.0 3 P13861,P10644 2 Interleukin 1 family signaling 0.2676831837748493 0.0589880643118627 0.9529616148571424 1.0 1.0 51 O00231,P49721,O43242,P60900,Q9UL46,O75832,Q14997,P28066,P09429,P62195,P20618,P61088,P28072,P28070 14 Cytosolic sensors of pathogen associated dna 0.2776905216874479 0.058983331199025 0.9529653847707384 1.0 1.0 17 O15160,Q9BUI4 2 Uch proteinases 0.278835328943474 0.0587012576791356 0.9531900575843212 1.0 1.0 49 P49721,O43242,P60900,Q9UL46,P25490,Q14997,P28066,Q9Y4E8,Q9H981,P62195,P20618,O75832,P28072,P28070 14 C type lectin receptors clrs 0.2598631017471997 0.0585905603305106 0.9532782295324468 1.0 1.0 51 P49721,O43242,P60900,Q9UL46,O75832,Q14997,P28066,P62195,P20618,P61088,P28072,P28070 12 Ros and rns production in phagocytes 0.2530953538487747 0.0585292160054996 0.9533270913704056 1.0 1.0 9 P21281,Q9Y5K8,P38606 3 Formation of xylulose 5 phosphate 0.2994312584107662 0.058317577342683 0.9534956666475524 1.0 1.0 3 P14550 1 Interleukin 1 signaling 0.2741845164079423 0.058308441492284 0.9535029436186796 1.0 1.0 49 O00231,P49721,O43242,P60900,Q9UL46,O75832,Q14997,P28066,P09429,P62195,P20618,P61088,P28072,P28070 14 Nuclear events stimulated by alk signaling in cancer 0.2623139736036104 0.0582222193811866 0.9535716222341516 1.0 1.0 12 Q9HC35,Q00610,Q86WB0 3 Sars cov 1 infection 0.2652380450895203 0.0581642585401056 0.9536177900555752 1.0 1.0 13 Q14457,P49841,P49840,P26572 4 Deadenylation dependent mrna decay 0.2997357805789025 0.057980874783128 0.9537638626067684 1.0 1.0 39 Q9NPD3,Q9NQT5,P11940,Q9NZN8,Q04637,Q9NPI6,Q969T7,Q6PGP7,Q6P2E9 9 Rhoa gtpase cycle 0.2764628023474905 0.0579590548028108 0.9537812432037373 1.0 1.0 48 Q92888,Q13464,O15498,Q07960,P30519,Q15904,Q9H8V3,Q9UDY2,Q14155,P42166,Q8NBN3,P14923,P52565 13 Resolution of abasic sites ap sites 0.2943914875716001 0.0576238350447525 0.954048263595224 1.0 1.0 27 P56282,P15927 2 Fceri mediated nf kb activation 0.2867736674216465 0.0576069942131959 0.954061678350844 1.0 1.0 45 P49721,O43242,P60900,Q9UL46,O75832,Q14997,P28066,P62195,P20618,P61088,P28072,P28070 12 Mhc class ii antigen presentation 0.1986795324507533 0.0570134118122532 0.9545345114387124 1.0 1.0 50 P61163,Q00610,O94979,Q9UJW0,Q96FJ2,Q9Y6G9,O00139,P53680,Q13409 9 Copi mediated anterograde transport 0.1962518785098184 0.0570077551567586 0.9545390174680806 1.0 1.0 50 Q01082,O60763,P61163,P62820,O15498,P35606,P84085,Q9UJW0,P48444,Q96FJ2,Q9Y6G9,Q12955,Q14789,Q13409,P24390,P18085 16 Meiosis 0.292733230455972 0.0565286562358341 0.9549206676423336 1.0 1.0 28 P20700,Q92878,Q8N3U4,Q9UH99,Q13472,Q8WXH0,O60216,Q15554,P15927,P02545,Q13535,P54132,P49959,Q14683,P27694 15 Reproduction 0.292733230455972 0.0565286562358341 0.9549206676423336 1.0 1.0 28 P20700,Q92878,Q8N3U4,Q9UH99,Q13472,Q8WXH0,O60216,Q15554,P15927,P02545,Q13535,P54132,P49959,Q14683,P27694 15 Autophagy 0.2825290777320677 0.0561699121299022 0.9552064499498838 1.0 1.0 43 Q15388,Q7Z3C6,O95352,Q96FJ2,Q9Y6G9,Q8N4H5,Q13501,P19784,P50542,Q9Y4P1,P61088,Q14457,Q13409,A5D8V6 14 Rho gtpases activate wasps and waves 0.2722030860918022 0.0560051463376176 0.955337707413513 1.0 1.0 17 O15144 1 Hcmv infection 0.1954864973514427 0.0557567925910955 0.9555355558826903 1.0 1.0 48 Q96FJ2,A5D8V6 2 Signaling by the b cell receptor bcr 0.241651005437409 0.0556168692540991 0.9556470255837632 1.0 1.0 47 P49721,O43242,P60900,Q9UL46,Q14997,P28066,P62195,P20618,O75832,P28072,P28070 11 Base excision repair 0.2890445564771547 0.0546640905816273 0.9564060781309414 1.0 1.0 31 P56282,P15927,Q9NRF9 3 Defective cftr causes cystic fibrosis 0.2613185218327619 0.0541824902483428 0.956789770947848 1.0 1.0 43 P49721,O43242,P60900,Q9UL46,Q14997,P28066,P62195,P20618,O75832,P28072,P28070 11 Recruitment of mitotic centrosome proteins and complexes 0.2861972981883924 0.0538812205800891 0.9570297987345028 1.0 1.0 32 P61163,Q96CW5,Q15154,P53350,Q9H6D7,Q13409,Q9UIS9 7 Interleukin 12 family signaling 0.2821807986342011 0.0528611432462583 0.957842544284135 1.0 1.0 30 P60953,Q99439,Q9UL46,P78417,Q00169,Q9H3K6,O00170,Q13126 8 Dna double strand break response 0.2731769389941388 0.0527224131359181 0.957953080758814 1.0 1.0 21 P61088,Q9NXR7 2 Mitochondrial biogenesis 0.2757234365631484 0.0517682663692429 0.9587133414010932 1.0 1.0 33 Q13505 1 Protein folding 0.2743711050190809 0.0515292835458256 0.9589037679457408 1.0 1.0 33 Q99471,P61962,P49368,O15212,Q15477,O75347,P19784,Q99832,P51784 9 Rho gtpases activate pkns 0.2664648148759265 0.0514773018316387 0.9589451883807848 1.0 1.0 19 Q04917,O14974,Q7Z406,P60660 4 Nuclear envelope breakdown 0.1711495006080343 0.0513436399572633 0.9590516942840994 1.0 1.0 41 P20700,P14635,P53350,P02545,P49790,Q86Y07,P35658,P42166,P50402,Q9BW27,Q8NC56,Q99567,Q8N1F7,O15504 14 Hats acetylate histones 0.2719154702895822 0.0512442354853097 0.9591309033067784 1.0 1.0 23 Q9ULM3,Q9H9T3 2 Rab regulation of trafficking 0.2443257977152053 0.0505764361527484 0.9596630400144964 1.0 1.0 38 O95248,O43617,Q9Y296,Q5VZ89 4 Recruitment of numa to mitotic centrosomes 0.2630215967605187 0.0501940209546654 0.9599677761369898 1.0 1.0 34 P61163,Q96CW5,Q15154,P53350,Q9H6D7,Q13409,Q9UIS9 7 Rhog gtpase cycle 0.2264761582472269 0.0499508225544162 0.9601615772792268 1.0 1.0 38 P60953,Q96JJ3,O15498,Q07960,Q9BSJ8,Q14185,Q86Y07,Q13112,P42166,P52565 10 Regulation of plk1 activity at g2 m transition 0.2089230000745829 0.0496538566399832 0.9603982281351487 1.0 1.0 38 P61163,O14974,Q15154,P53350,Q9H6D7,Q13409,Q9UIS9 7 Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.2483457397204329 0.0493343627402404 0.9606528353414596 1.0 1.0 13 Q13371,P49368,P17987,P19784,P50991,Q99832 6 Oncogenic mapk signaling 0.2647423254365814 0.0490545588031045 0.9608758166010012 1.0 1.0 29 O95352,Q6WCQ1,P31946,P18206,Q96PU8,Q99956 6 Diseases of mitotic cell cycle 0.2497472495872264 0.048918481455939 0.9609842604220178 1.0 1.0 14 Q00534,Q96DE5,Q9UJX3,Q16763,Q9H1A4 5 Protein ubiquitination 0.2610677267985627 0.04801673438549 0.9617029058787888 1.0 1.0 24 Q14527,A0AVT1,P55072,P45974,Q6PD62,P04439,P61086,P50542,Q93009,Q16763,P61088,P22314,Q8N7H5,Q5VTR2 14 Anchoring of the basal body to the plasma membrane 0.234331627776944 0.0474618434263005 0.9621451405799356 1.0 1.0 33 P61163,Q15154,P53350,Q9H6D7,Q13409,Q9UIS9 6 Translocation of slc2a4 glut4 to the plasma membrane 0.2333112437405247 0.0474125610735391 0.9621844179907028 1.0 1.0 33 Q04917,O00471,Q9BZE9,Q9NV70 4 Aurka activation by tpx2 0.2051328417827315 0.0466018458795539 0.9628305608314632 1.0 1.0 33 P61163,Q15154,P53350,Q9H6D7,Q13409,Q9UIS9 6 Hcmv late events 0.2221860977864133 0.0464281867001988 0.9629689709929684 1.0 1.0 32 A5D8V6 1 Rhoc gtpase cycle 0.2182657011141465 0.0463047131068755 0.963067382824586 1.0 1.0 32 P42166 1 Copii mediated vesicle transport 0.2388887909486874 0.0454531848590165 0.96374608937292 1.0 1.0 28 O60763,P62820,O15498,Q9Y296,O94979,Q8IUR0,O43617 7 Death receptor signalling 0.2301227131082542 0.0452466061755219 0.9639107459103042 1.0 1.0 29 Q92888,P42575,Q9NQC3,Q9H8V3,Q14155,P52565,P78536 7 Regulation by c flip 0.4208554480174745 0.0451554218045215 0.9639834262264216 1.0 1.0 2 P49327 1 Caspase activation via death receptors in the presence of ligand 0.4208554480174745 0.0451554218045215 0.9639834262264216 1.0 1.0 2 P49327 1 Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.1923881500332729 0.0446426020796898 0.964392184942454 1.0 1.0 30 P61163,Q02790,Q9UJW0,Q96FJ2,Q9Y6G9,Q14204,P25685,Q13409,P31948 9 Small interfering rna sirna biogenesis 0.2462344794911973 0.0445746870362798 0.964446319418282 1.0 1.0 3 Q99598 1 Rhoq gtpase cycle 0.2416747129044382 0.044147929663472 0.9647864876570428 1.0 1.0 22 Q68EM7,Q07960,Q14155,Q13112,P14923 5 Rhod gtpase cycle 0.2001801993392074 0.0435879401313158 0.965232864943167 1.0 1.0 28 Q68EM7,Q07960,Q9BSJ8,O60610,O60879,P12814,P42166 7 Telomere c strand lagging strand synthesis 0.2314406360753613 0.0426940834095839 0.9659453960261912 1.0 1.0 22 P49642,P28340,P35249,P15927,P54132,P40938,P18858,Q15554,P27694 9 Meiotic synapsis 0.2324194966183564 0.0422883615464696 0.9662688231282428 1.0 1.0 18 P20700,Q9UH99,Q14683,Q8WXH0,O60216,P02545,Q15554,Q13535,Q8N3U4 9 Lagging strand synthesis 0.2284279687857288 0.0416928765611041 0.966743532705882 1.0 1.0 19 P49642,P28340,P35249,P15927,P18858,P40938,P27694 7 Semaphorin interactions 0.2235019049932735 0.0407134847013635 0.9675243112724884 1.0 1.0 17 Q13464,Q9Y490,P60660,Q7Z406,P49841 5 Rhobtb2 gtpase cycle 0.2128545039633725 0.0398370127777365 0.9682230677112034 1.0 1.0 19 Q13618,Q12792,P12814,Q99832,Q16543,Q8WWQ0 6 Kinesins 0.199799889487449 0.0384366141109444 0.9693395687009414 1.0 1.0 18 O00139 1