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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:87fd5937c4aeb9f3a05e58742708e54f6a32e09e2c31527408cd2bdb3c33a2aa
+size 73007

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3210,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.830188679245283
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C408/C408_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.909260991580924	1.7955591317482569	0.0725646604937597	0.9815484461528992	0.4242317923097751	3	Q9HB40,P10619	2
+Histidine acid phosphatase active site [IPR033379]	0.9230049875311732	1.1570875709678918	0.2472365841430828	0.9999997096641076	0.6025732803475672	2	Q9NPH0	1
+Cysteine peptidase, cysteine active site [IPR000169]	0.4936077330838623	0.3121240608782715	0.754946241390337	1.0	1.0	3	P17655,P07384	2
+ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]	0.5077930174563666	0.0775117565360872	0.938216439048958	1.0	1.0	2	P53597	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CASP6", "CDC42BPB", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MARK3", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNGTT", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK2", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CAPN1", "CAPN2", "CTSA", "SCPEP1", "SUCLG1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

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+{}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:49838ce78d457bea616cc156df3071f9e4bee1ec9bac251995154112b2592a74
+size 71391

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3210,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 4.870967741935484
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C408/C408_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,2 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M16, zinc-binding site [IPR001431]	0.5532014581048987	0.8823574279883835	0.3775835498820035	0.9999995864643728	0.8893027579894659	5	Q10713,O43847	2

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "ARG2", "AURKA", "AURKB", "BPNT1", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HASPIN", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MARK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK3", "STK4", "TAOK2", "TKT", "TTK", "TUBB", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["NRDC", "PMPCA"]}

interpro_conserved_site/advanced/idx2term.json

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+{}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter-like, conserved site [IPR017871]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:4eec79f845cd42d512b23abad07f58ab15f7366de14acaaa411b312be684cbd4
+size 78249

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3210,
+    "annotations_size": 277,
+    "title": "Average number of proteins per term",
+    "value": 2.7617328519855597
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C408/C408_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Proteasome beta-type subunit, conserved site [IPR016050]	0.753230347912793	1.874111970843918	0.0609149937164272	0.9999999725046592	0.5912717584645759	8	P28070,P28074,P28072,P49721	4
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.709027005966161	1.714379392317492	0.0864590707402137	0.999999999986767	0.6218114232546066	6	Q13535,P78527,Q9UBF8	3
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.8158076791528561	1.440090480080656	0.1498418021181291	1.0	0.6917696531120295	3	Q8N4Q0	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.8038498168925434	1.3942682351774682	0.1632366193329657	1.0	0.6965145610998852	3	Q08426	1
+Haem oxygenase conserved site [IPR018207]	0.9841022443890276	1.3776211481052816	0.1683202880347833	1.0	0.6965145610998852	2	P30519	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6254561243151125	1.3266987869815643	0.1846083423980733	1.0	0.7305215834895188	6	Q14566,P33993,P33992	3
+Sterol reductase, conserved site [IPR018083]	0.9470074812967588	1.2434325900860053	0.2137084670798019	1.0	0.768795394559807	2	Q14739	1
+Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.7912228135332068	2	P05067	1
+Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.7912228135332068	2	P05067	1
+Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.7912228135332068	2	P05067	1
+Ribosomal protein L24/L26, conserved site [IPR005825]	0.9021197007481312	1.082453119239675	0.2790512359042787	1.0	0.8868248827540515	2	P61254	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.7019020891799277	1.0052260380307512	0.3147880199925632	1.0	0.917130768352105	3	Q9BXS5,Q9Y2T2	2
+4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]	0.6580510958905421	0.8420292940337614	0.3997715564555146	1.0	0.9629280098971962	3	O00217	1
+Ribosomal S11, conserved site [IPR018102]	0.8216957605985057	0.8026204390614207	0.4221941510491132	1.0	0.9913581039972305	2	P62263	1
+Intermediate filament protein, conserved site [IPR018039]	0.4753085789969227	0.5958099890632569	0.5513021698113363	1.0	0.9956166458366488	8	P08670,P07196	2
+ABC transporter-like, conserved site [IPR017871]	0.4295310013056896	0.320771308738935	0.748383703648464	1.0	0.9956166458366488	14	O15439,P28288,P33897,Q03518,O75027,P08183,Q03519	7
+Dynamin, GTPase region, conserved site [IPR019762]	0.4879950109136131	0.2979513111231003	0.7657403247973202	1.0	0.9956166458366488	3	P50570,O00429	2
+Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]	0.3854689919479205	0.2658297795558984	0.7903703073469455	1.0	0.9956166458366488	6	Q08426,Q13011	2
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.3984592287478994	0.1233750895015654	0.9018100820517998	1.0	0.9956166458366488	3	P09429	1
+ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]	0.5077930174563666	0.0775117565360872	0.938216439048958	1.0	0.9956166458366488	2	P53597	1
+DNA ligase, ATP-dependent, conserved site [IPR016059]	0.496882793017464	0.0686173453280284	0.9452942118332366	1.0	0.9956166458366488	2	P49916	1
+Ribosomal protein L24e, conserved site [IPR023442]	0.4940773067331739	0.0664954097606445	0.9469834121036512	1.0	0.9956166458366488	2	Q9UHA3	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.3410868615528458	0.0417020235904224	0.966736240774326	1.0	0.9956166458366488	16	Q9UPU5	1
+Ribosomal protein S5, N-terminal, conserved site [IPR018192]	0.420511221945146	0.0309667651685853	0.9752960445078218	1.0	0.9956166458366488	2	P15880	1
+Aminotransferase, class IV, conserved site [IPR018300]	0.4173940149626015	0.0301505990375877	0.975946946856711	1.0	0.9956166458366488	2	P54687	1
+IMP dehydrogenase / GMP reductase, conserved site [IPR015875]	0.4142768079800564	0.0293767818097705	0.9765640902430814	1.0	0.9956166458366488	2	P20839	1
+Polyamine biosynthesis domain, conserved site [IPR030373]	0.3706359102244463	0.0221689983030898	0.9823131472806944	1.0	0.9956166458366488	2	P52788	1
+EGF-like calcium-binding, conserved site [IPR018097]	0.3151496259351704	0.0190091650528361	0.9848337940766853	1.0	0.9956166458366488	2	O94813	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPA, conserved site [IPR022658]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "Zinc finger, XPA-type, conserved site [IPR022652]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CHAF1B", "CHD1", "CHD1L", "CHD2", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COQ6", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EHHADH", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GRHPR", "GRWD1", "GSPT1", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KAT2A", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF18A", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NF2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCGF6", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL3", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TTF2", "TUBB", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "UIMC1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPA", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC4", "ABCD1", "ABCD3", "AP1M1", "AP3M1", "APP", "ATR", "BCAT1", "DNM1L", "DNM2", "ECH1", "EHHADH", "HMGB1", "HMOX2", "IMPDH1", "LBR", "LIG3", "MCM5", "MCM6", "MCM7", "NDUFS8", "NEFL", "PI4KB", "PRKDC", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "RPL26", "RPS14", "RPS2", "RSL24D1", "SLIT2", "SMS", "SUCLG1", "TAP1", "TAP2", "USP24", "VIM", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "ABC transporter type 1, transmembrane domain [IPR011527]", "1": "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "2": "ABC transporter-like, ATP-binding domain [IPR003439]", "3": "TGS [IPR004095]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6e83cc93f6366fcc39f2acdad6b2012c6f20cc7f7be73a827c00fa319adead77
+size 118213

interpro_domain/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	2	6	2.381598188573668	0.0172376946552343	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	0.0378187125466048	4.800413077288208e-05	0.0007187465088185	0.0053031795330487
+Aminopeptidase N-like , N-terminal domain [IPR045357]	2	6	2.381598188573668	0.0172376946552343	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	0.0378187125466048	4.800413077288208e-05	0.0007187465088185	0.0053031795330487
+KOW [IPR005824]	3	6	2.2661072739683967	0.0234448159972411	2.9393203883495147	5.349514563106796	-0.3288066047063325	0.4912799084151893	1.4593879300449948	0.8120301522939392	0.9166573511426293	0.2932365525740842	1.0	0.0331691185540615	0.0660385900079411	0.1577810442013011	0.0001708540892308

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3210,
+    "annotations_size": 2696,
+    "title": "Average number of proteins per term",
+    "value": 2.1839762611275964
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C408/C408_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,245 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.8599613981089556	2.381598188573668	0.0172376946552343	1.0	0.7710454222942713	6	P09960,P55786	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.8599613981089556	2.381598188573668	0.0172376946552343	1.0	0.7710454222942713	6	P09960,P55786	2
+Reticulon [IPR003388]	0.9054368845415972	2.270852858794193	0.0231558868229555	1.0	0.7710454222942713	4	O95197	1
+KOW [IPR005824]	0.8330371700073781	2.2661072739683967	0.0234448159972411	1.0	0.7710454222942713	6	P61254,Q92917,Q96A35	3
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.8992514036182236	2.245948024225131	0.0247073372883424	1.0	0.7710454222942713	4	Q96G23,P27544,Q15629	3
+ERAP1-like C-terminal domain [IPR024571]	0.8863738603534785	2.1938918561422605	0.0282431850047832	1.0	0.7710454222942713	4	P55786	1
+Major facilitator superfamily domain [IPR020846]	0.8601668188168234	2.087100705124643	0.0368790323501031	1.0	0.7710454222942713	4	P53985,Q7L0J3	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.742292582022722	1.8654627199417595	0.062116573029368	1.0	0.7710454222942713	6	O43169,Q9UMX5	2
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7419707124042778	1.8640111856387505	0.0623201335438758	1.0	0.7710454222942713	6	Q9HD20,P23634	2
+MHC class I-like antigen recognition-like [IPR011161]	0.7968725671245813	1.8246995914079236	0.0680463749686921	1.0	0.7710454222942713	4	P04439,Q9UNN8	2
+Extended PHD (ePHD) domain [IPR034732]	0.8835337807028038	1.6983487087413438	0.089441966586774	1.0	0.7710454222942713	3	Q03164	1
+LEM domain [IPR003887]	0.7046222257681649	1.69421816572427	0.0902238341664025	1.0	0.7710454222942713	6	Q86XL3,P42166	2
+Polyketide synthase, enoylreductase domain [IPR020843]	0.6998978951725874	1.672555674004366	0.0944147991481836	1.0	0.7710454222942713	6	Q8N4Q0	1
+Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]	0.7298712911242179	1.6660491952791183	0.0957036163462459	1.0	0.7710454222942713	5	P25398	1
+Zinc finger, CHHC-type [IPR012996]	0.8550046772684732	1.5899053105190843	0.1118561504513449	1.0	0.7710454222942713	3	P31943,P55795	2
+Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]	0.6859664159835218	1.5681496755544388	0.1168462057286967	1.0	0.7710454222942713	8	Q13535,P78527,Q9BTU6,Q9UBF8	4
+N-acetylgalactosaminyltransferase [IPR045885]	0.7181251699457598	1.4908061276450502	0.1360124025300741	1.0	0.7839453846564269	4	Q8N4A0	1
+FATC domain [IPR003152]	0.7091688128495359	1.4524583502885728	0.1463742019486571	1.0	0.8053568335787339	4	Q13535,P78527	2
+PIK-related kinase [IPR014009]	0.7091688128495359	1.4524583502885728	0.1463742019486571	1.0	0.8053568335787339	4	Q13535,P78527	2
+PIK-related kinase, FAT [IPR003151]	0.7091688128495359	1.4524583502885728	0.1463742019486571	1.0	0.8053568335787339	4	Q13535,P78527	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.6674593066208758	1.4430174263196158	0.1490155623137727	1.0	0.8099716854797004	10	O15439,P28288,P33897,Q03518,O14678,O75027,P08183,Q03519	8
+Mu homology domain [IPR028565]	0.7021210230817337	1.4222488970012848	0.1549540084190934	1.0	0.8148509211586987	4	Q9BXS5,Q9Y2T2,P48444	3
+Kinesin-associated [IPR032405]	0.8083159104795474	1.4113859895502252	0.1581308318178362	1.0	0.8148509211586987	3	Q15058	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.6961218028584707	1.3965148994197931	0.1625594970579296	1.0	0.8148509211586987	4	Q4J6C6	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.8038498168925434	1.3942682351774682	0.1632366193329657	1.0	0.8148509211586987	3	Q08426	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.8038498168925434	1.3942682351774682	0.1632366193329657	1.0	0.8148509211586987	3	Q08426	1
+FAD dependent oxidoreductase [IPR006076]	0.692668057003758	1.381693258189553	0.1670659053263334	1.0	0.8148509211586987	4	Q96CU9	1
+NOPS [IPR012975]	0.7991892734643047	1.3764017278121945	0.1686972933582473	1.0	0.8148509211586987	3	Q15233,P23246	2
+Alcohol dehydrogenase, N-terminal [IPR013154]	0.6632980815094885	1.3712939287605417	0.170283347534859	1.0	0.8148509211586987	5	Q8N4Q0	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.6868702827131072	1.3568036395183674	0.1748436107818951	1.0	0.8169693793268412	4	O00217,Q16134	2
+MD-2-related lipid-recognition domain [IPR003172]	0.9763092269326684	1.349381398836007	0.1772144923653531	1.0	0.8169693793268412	2	P17900	1
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.6541096849368624	1.3303220207763953	0.1834121947975486	1.0	0.8169693793268412	5	P05023,P23634	2
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.6541096849368624	1.3303220207763953	0.1834121947975486	1.0	0.8169693793268412	5	P05023,P23634	2
+MCM domain [IPR001208]	0.6254561243151125	1.3266987869815643	0.1846083423980733	1.0	0.8169693793268412	6	Q14566,P33993,P33992	3
+MCM N-terminal domain [IPR027925]	0.6254561243151125	1.3266987869815643	0.1846083423980733	1.0	0.8169693793268412	6	Q14566,P33993,P33992	3
+MCM, AAA-lid domain [IPR041562]	0.6254561243151125	1.3266987869815643	0.1846083423980733	1.0	0.8169693793268412	6	Q14566,P33993,P33992	3
+MCM OB domain [IPR033762]	0.6254561243151125	1.3266987869815643	0.1846083423980733	1.0	0.8169693793268412	6	Q14566,P33993,P33992	3
+Zinc finger, RanBP2-type [IPR001876]	0.6362514354613485	1.3178427955382388	0.1875562785013709	1.0	0.8169693793268412	9	P35637,O95218,Q01844,P52756	4
+FAD-binding domain, PCMH-type [IPR016166]	0.9591645885286788	1.28733491068933	0.1979775804392105	1.0	0.8241463353142452	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.9591645885286788	1.28733491068933	0.1979775804392105	1.0	0.8241463353142452	2	Q15392	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.6621045261158889	1.2504391509481554	0.2111391703234093	1.0	0.8378796848721761	4	P14866,Q8WVV9	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6216005101090022	1.2495206386973912	0.2114747096075069	1.0	0.8378796848721761	9	Q9HCL2,Q8NF37,Q9NUQ2	3
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7595445207833836	1.2244631508653576	0.2207775590085159	1.0	0.8489026757820904	3	P04439	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7595445207833836	1.2244631508653576	0.2207775590085159	1.0	0.8489026757820904	3	P04439	1
+Immunoglobulin C1-set [IPR003597]	0.7595445207833836	1.2244631508653576	0.2207775590085159	1.0	0.8489026757820904	3	P04439	1
+Acyl-CoA oxidase, C-terminal [IPR002655]	0.9407730673316708	1.2209578281710969	0.2221019874656693	1.0	0.8489026757820904	2	Q15067	1
+Peptidase M28 [IPR007484]	0.757379775400183	1.216179029388431	0.2239167303845213	1.0	0.8489026757820904	3	Q969V3	1
+Ribosomal protein L18e/L15P [IPR021131]	0.7526367764747282	1.198036853281492	0.230902670150547	1.0	0.8489026757820904	3	P46776	1
+Amyloidogenic glycoprotein, heparin-binding [IPR015849]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.8489026757820904	2	P05067	1
+Beta-amyloid precursor protein C-terminal [IPR019543]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.8489026757820904	2	P05067	1
+Pancreatic trypsin inhibitor Kunitz domain [IPR002223]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.8489026757820904	2	P05067	1
+Amyloidogenic glycoprotein, E2 domain [IPR024329]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.8489026757820904	2	P05067	1
+Amyloidogenic glycoprotein, copper-binding [IPR011178]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.8489026757820904	2	P05067	1
+Amyloidogenic glycoprotein, extracellular [IPR008154]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.8489026757820904	2	P05067	1
+Zinc finger, CW-type [IPR011124]	0.747187529846318	1.177209665144264	0.23911183190426	1.0	0.8600898811558507	3	Q8NB78	1
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.733954863466118	1.1267249683595002	0.2598587824044696	1.0	0.8790204232904014	3	Q7L576	1
+Peptidase M16, C-terminal [IPR007863]	0.5858630357865007	1.1210658317152522	0.2622598414466688	1.0	0.8791036083949875	7	Q5JRX3,O43847	2
+Peptidase M16, N-terminal [IPR011765]	0.5858630357865007	1.1210658317152522	0.2622598414466688	1.0	0.8791036083949875	7	Q5JRX3,O43847	2
+Glutamine amidotransferase type 2 domain [IPR017932]	0.7302775179295315	1.112722725035372	0.2658275324226453	1.0	0.8791036083949875	3	Q06203,P08243	2
+Agenet-like domain [IPR008395]	0.7290302463361419	1.1079765707840752	0.2678719344803792	1.0	0.8791036083949875	3	P51116,Q06787	2
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7290302463361419	1.1079765707840752	0.2678719344803792	1.0	0.8791036083949875	3	P51116,Q06787	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7290302463361419	1.1079765707840752	0.2678719344803792	1.0	0.8791036083949875	3	P51116,Q06787	2
+Fxr1, tudor domain [IPR041560]	0.7290302463361419	1.1079765707840752	0.2678719344803792	1.0	0.8791036083949875	3	P51116,Q06787	2
+Ribosomal protein L26/L24, KOW domain [IPR041988]	0.9021197007481312	1.082453119239675	0.2790512359042787	1.0	0.8914332766126465	2	P61254	1
+Rhodanese-like domain [IPR001763]	0.6197754210854639	1.069205668339705	0.2849770051261888	1.0	0.8924895817915544	4	P40818,Q8NCN5,P25325	3
+Kinesin-like [IPR022164]	0.7134277000866911	1.0487570010140974	0.2942899722398018	1.0	0.8997135039755211	3	Q12756	1
+Cyclin-like [IPR013763]	0.7100093545369497	1.0358251619767191	0.3002837165646863	1.0	0.9086025812103192	3	O95067,P14635	2
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.7040848144683471	1.0134539018963415	0.3108434042764174	1.0	0.9090758177715124	3	Q1KMD3,Q00839	2
+Peptidase M24 [IPR000994]	0.5533381592075356	0.9686870803409088	0.3327013406048151	1.0	0.9176065438294748	7	P53582,P50579	2
+Phospholipase D/Transphosphatidylase [IPR001736]	0.8665835411471341	0.9570028117558992	0.3385658358083607	1.0	0.9176065438294748	2	Q8IV08	1
+Fibronectin type III [IPR003961]	0.5685067444684125	0.9494549595715328	0.3423892692290438	1.0	0.9204740074532556	5	Q15375,P15260	2
+APC10/DOC domain [IPR004939]	0.6844681816931724	0.9398207392902652	0.3473095188767809	1.0	0.9235297126896058	3	O75592	1
+Saposin B type domain [IPR008139]	0.856920199501249	0.9233224783066758	0.3558391771378457	1.0	0.9246819227069314	2	P07602	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8553615960099765	0.9179105810397088	0.3586656816446503	1.0	0.9297718054942088	2	P98179	1
+Tudor domain [IPR002999]	0.5461703432159006	0.9165990447403009	0.3593527851315312	1.0	0.93050182219442	8	Q14739,Q16637,Q9Y2W6	3
+DNA mismatch repair protein MutS, core [IPR007696]	0.6545057686311151	0.8290520715913391	0.4070749427289941	1.0	0.96716746895572	3	P20585,P43246	2
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.6545057686311151	0.8290520715913391	0.4070749427289941	1.0	0.96716746895572	3	P20585,P43246	2
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.6545057686311151	0.8290520715913391	0.4070749427289941	1.0	0.96716746895572	3	P20585,P43246	2
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.6545057686311151	0.8290520715913391	0.4070749427289941	1.0	0.96716746895572	3	P20585,P43246	2
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.6526299046584018	0.822201610716475	0.410962162209235	1.0	0.96716746895572	3	O43823	1
+Translation initiation factor IF2/IF5 domain [IPR002735]	0.8201371571072337	0.7973663030366798	0.4252383235790038	1.0	0.969917529923007	2	P55010	1
+TOG domain [IPR034085]	0.515168842292892	0.7918920959934527	0.4284235960632623	1.0	0.9732075757470868	7	O75122,Q92616,Q7Z460	3
+Ras-associating (RA) domain [IPR000159]	0.5526523626138877	0.7881181671133572	0.4306275896300651	1.0	0.9756067072627356	4	Q96L92	1
+Cold shock domain [IPR011129]	0.5504368530259428	0.7790839513825418	0.4359302632055999	1.0	0.9772729693968848	4	Q9Y2V2,P67809	2
+Cold-shock (CSD) domain [IPR019844]	0.5504368530259428	0.7790839513825418	0.4359302632055999	1.0	0.9772729693968848	4	Q9Y2V2,P67809	2
+Cold-shock protein, DNA-binding [IPR002059]	0.5504368530259428	0.7790839513825418	0.4359302632055999	1.0	0.9772729693968848	4	Q9Y2V2,P67809	2
+HECT domain [IPR000569]	0.5201472374774305	0.7787659883509932	0.4361175763367151	1.0	0.9772729693968848	9	Q14669,P46934,Q96J02	3
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.8126558603491291	0.7722627227418716	0.4399588390314484	1.0	0.9778475103287592	2	Q96CW5	1
+Gamma tubulin complex component, C-terminal [IPR040457]	0.8126558603491291	0.7722627227418716	0.4399588390314484	1.0	0.9778475103287592	2	Q96CW5	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8114089775561117	0.7680980573555098	0.442428930964301	1.0	0.9787087992551768	2	O43390	1
+EB1, C-terminal [IPR004953]	0.8026807980049897	0.7391072028393683	0.4598419034316137	1.0	0.9964451612415433	2	Q15555	1
+L27 domain, C-terminal [IPR014775]	0.5186841043505138	0.73374086763908	0.4631066859020718	1.0	0.999634376654246	5	Q9NZW5,O14936	2
+W2 domain [IPR003307]	0.502375771774769	0.7335615106958021	0.4632160261465978	1.0	0.999634376654246	7	Q13144	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.79769326683292	0.7226734360130745	0.4698805394186374	1.0	1.0	2	Q96AE4	1
+EF-hand, Ca insensitive [IPR014837]	0.6214530714062916	0.7101933701844274	0.4775842315830061	1.0	1.0	3	O43707,P12814	2
+CARG-binding factor, N-terminal [IPR012956]	0.7858478802992543	0.6840564230287322	0.4939395375500723	1.0	1.0	2	Q99729	1
+Exportin-2, central domain [IPR013713]	0.6120985344558669	0.677371803988424	0.4981700833597977	1.0	1.0	3	O95373,O15397	2
+Fatty acid desaturase domain [IPR005804]	0.7833541147132201	0.6760044117840962	0.4990378439959402	1.0	1.0	2	O15121	1
+AP complex, mu/sigma subunit [IPR022775]	0.5030995209183647	0.6683415953934178	0.5039155675391778	1.0	1.0	5	Q9Y2T2,P48444	2
+Gelsolin-like domain [IPR007123]	0.5026500716712217	0.666475030795157	0.5051075183083145	1.0	1.0	5	O95486,Q13045	2
+PA domain [IPR003137]	0.7752493765586063	0.6500333090753775	0.5156707060233041	1.0	1.0	2	Q8TCT8	1
+GINS subunit, domain A [IPR021151]	0.7715087281795538	0.638152401991061	0.5233744779341902	1.0	1.0	2	Q9BRX5	1
+Zinc finger, CCHC-type [IPR001878]	0.4806733669563318	0.6362210263675573	0.5246323703165281	1.0	1.0	7	Q9NUD5	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.764650872817958	0.6165521688405105	0.5375301517736111	1.0	1.0	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.764650872817958	0.6165521688405105	0.5375301517736111	1.0	1.0	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.764650872817958	0.6165521688405105	0.5375301517736111	1.0	1.0	2	A1L0T0	1
+Patatin-like phospholipase domain [IPR002641]	0.7630922693266862	0.6116767171339165	0.5407516692478513	1.0	1.0	2	Q8IY17	1
+Intermediate filament, rod domain [IPR039008]	0.4753085789969227	0.5958099890632569	0.5513021698113363	1.0	1.0	8	P08670,P07196	2
+RBM1CTR [IPR012604]	0.752493765586038	0.5788693654541178	0.5626773222712607	1.0	1.0	2	P38159	1
+Cyclin, C-terminal domain [IPR004367]	0.7512468827930205	0.5750505174692684	0.5652571320252342	1.0	1.0	2	O95067	1
+Cyclin, N-terminal [IPR006671]	0.7512468827930205	0.5750505174692684	0.5652571320252342	1.0	1.0	2	O95067	1
+Copine, C2B domain [IPR037768]	0.5807330287311574	0.5706418482130275	0.5682424450779577	1.0	1.0	3	O75131	1
+Copine, C-terminal [IPR010734]	0.5807330287311574	0.5706418482130275	0.5682424450779577	1.0	1.0	3	O75131	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.4789508834338977	0.5624450733754949	0.573812816667413	1.0	1.0	11	Q9NWM8,O00170	2
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.4581772784019962	0.5544578621107525	0.5792655361287125	1.0	1.0	6	Q15428,Q12874,Q9ULV3,P43243,P09234	5
+BTB/POZ domain [IPR000210]	0.4915782907049302	0.5488836883167899	0.5830852729778466	1.0	1.0	4	Q9P2R3,Q9NXV2,Q08380	3
+MRH domain [IPR044865]	0.5735679701426928	0.5470837833177874	0.5843211728556255	1.0	1.0	3	P20645	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.4888718884208225	0.5388689631165077	0.5899772742664731	1.0	1.0	4	P07196	1
+SUN domain [IPR012919]	0.7384663341645918	0.5364304402862352	0.5916610981512909	1.0	1.0	2	Q9ULT8	1
+Dynamin, GTPase domain [IPR001401]	0.4881472239550747	0.5361977608643386	0.5918218808688347	1.0	1.0	4	O60313,P50570,O00429	3
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.5665731212971561	0.5244184437171966	0.5999875310997262	1.0	1.0	3	Q99797,P52888	2
+CBS domain [IPR000644]	0.4837907341182321	0.5202333796340204	0.6029009228549627	1.0	1.0	4	P51790	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.7288029925187067	0.5078951108173663	0.611526903674773	1.0	1.0	2	P51116	1
+Glycogen synthase kinase 3, catalytic domain [IPR039192]	0.7216334164588564	0.4871166510018958	0.6261756671019898	1.0	1.0	2	P49840	1
+CTP synthase GATase domain [IPR033828]	0.7166458852867869	0.4728679632727187	0.6363073825048742	1.0	1.0	2	P17812	1
+CTP synthase, N-terminal [IPR017456]	0.7166458852867869	0.4728679632727187	0.6363073825048742	1.0	1.0	2	P17812	1
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.7122817955112257	0.4605432779837449	0.6451263148547546	1.0	1.0	2	O94979	1
+Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]	0.7013715710723233	0.4303368123625433	0.6669506524626887	1.0	1.0	2	Q9H993	1
+Cysteine-rich flanking region, C-terminal [IPR000483]	0.6963840399002534	0.4168263809238409	0.6768054047858452	1.0	1.0	2	Q13641	1
+Leucine-rich repeat N-terminal domain [IPR000372]	0.6963840399002534	0.4168263809238409	0.6768054047858452	1.0	1.0	2	Q13641	1
+PUA domain [IPR002478]	0.4537727984792102	0.4150907859172058	0.6780754443716523	1.0	1.0	4	Q9ULC4	1
+FYVE zinc finger [IPR000306]	0.5157468038665268	0.3713023393043686	0.7104123557910431	1.0	1.0	3	Q7Z3T8,O14964	2
+Zinc finger, FYVE-related [IPR017455]	0.5157468038665268	0.3713023393043686	0.7104123557910431	1.0	1.0	3	Q7Z3T8,O14964	2
+Sec63 domain [IPR004179]	0.5123168069847057	0.3618046865811159	0.7174979897005493	1.0	1.0	3	Q8N3C0,Q9UGP8	2
+BAT2, N-terminal [IPR009738]	0.5070159027128031	0.3473586766816398	0.7283218740454496	1.0	1.0	3	Q9Y520,Q5JSZ5	2
+Proteasome alpha-subunit, N-terminal domain [IPR000426]	0.4103843524875124	0.3439633423276831	0.7308738544782276	1.0	1.0	7	P60900	1
+Zinc finger, Sec23/Sec24-type [IPR006895]	0.4307548346849619	0.3411393571634707	0.7329986736574055	1.0	1.0	4	O95486,Q15436,O95487	3
+Sec23/Sec24 beta-sandwich [IPR012990]	0.4307548346849619	0.3411393571634707	0.7329986736574055	1.0	1.0	4	O95486,Q15436,O95487	3
+Sec23/Sec24, helical domain [IPR006900]	0.4307548346849619	0.3411393571634707	0.7329986736574055	1.0	1.0	4	O95486,Q15436,O95487	3
+Sec23/Sec24, trunk domain [IPR006896]	0.4307548346849619	0.3411393571634707	0.7329986736574055	1.0	1.0	4	O95486,Q15436,O95487	3
+ABC transporter-like, ATP-binding domain [IPR003439]	0.4295310013056896	0.320771308738935	0.748383703648464	1.0	1.0	14	O15439,P28288,P33897,Q03518,O75027,P08183,Q03519	7
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4110580455600267	0.3191981948708259	0.7495762257110126	1.0	1.0	9	Q15067,O15254	2
+Lamin tail domain [IPR001322]	0.4939195509822112	0.312921605152505	0.7543402227699787	1.0	1.0	3	P20700,P02545	2
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.6543017456359149	0.3109923121466418	0.7558064660720871	1.0	1.0	2	P43246	1
+Bms1/Tsr1-type G domain [IPR030387]	0.6536783042394064	0.3095415245849245	0.7569096299928293	1.0	1.0	2	Q2NL82	1
+AARP2CN [IPR012948]	0.6536783042394064	0.3095415245849245	0.7569096299928293	1.0	1.0	2	Q2NL82	1
+Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]	0.6536783042394064	0.3095415245849245	0.7569096299928293	1.0	1.0	2	Q2NL82	1
+Dynein heavy chain region D6 P-loop domain [IPR004273]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, tail [IPR013594]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, AAA module D4 [IPR024317]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, linker [IPR013602]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain AAA lid domain [IPR041658]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, ATP-binding dynein motor region [IPR035706]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, coiled coil stalk [IPR024743]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+Dynein heavy chain, C-terminal domain [IPR041228]	0.6490024937655909	0.2987760233099801	0.7651109464111556	1.0	1.0	2	Q8NCM8	1
+GTPase effector domain [IPR020850]	0.4879950109136131	0.2979513111231003	0.7657403247973202	1.0	1.0	3	P50570,O00429	2
+Dynamin GTPase effector [IPR003130]	0.4879950109136131	0.2979513111231003	0.7657403247973202	1.0	1.0	3	P50570,O00429	2
+Dynamin stalk domain [IPR000375]	0.4879950109136131	0.2979513111231003	0.7657403247973202	1.0	1.0	3	P50570,O00429	2
+C2 DOCK-type domain [IPR027007]	0.6424563591022494	0.2840507387809158	0.7763714973769851	1.0	1.0	2	Q14185	1
+DOCKER domain [IPR027357]	0.6424563591022494	0.2840507387809158	0.7763714973769851	1.0	1.0	2	Q14185	1
+Pre-PUA domain [IPR041366]	0.6349750623441447	0.2677258904278374	0.7889103193995495	1.0	1.0	2	Q9ULC4	1
+NUC153 [IPR012580]	0.6293640897755663	0.2558413513406068	0.7980733424585278	1.0	1.0	2	Q9H501	1
+Sec24-like, trunk domain [IPR041742]	0.4676698054070981	0.2496309079123975	0.8028727940818063	1.0	1.0	3	O95486	1
+USP8 dimerisation domain [IPR015063]	0.6231296758104792	0.2430029574793257	0.8080031063763622	1.0	1.0	2	O95630	1
+CTLH, C-terminal LisH motif [IPR006595]	0.3922796120764267	0.2332361122986077	0.8155780654360529	1.0	1.0	4	Q9H7D7,Q9UL63	2
+CRIB domain [IPR000095]	0.4596195821640129	0.2318453563066406	0.8166581274426172	1.0	1.0	3	Q13177,Q9Y5S2	2
+Bromodomain [IPR001487]	0.4058460368555305	0.2145599243796181	0.8301104419084828	1.0	1.0	16	Q03164	1
+SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]	0.4483941378235004	0.2083743548865318	0.8349366786766312	1.0	1.0	3	Q96P11,P46087	2
+Glutamine amidotransferase [IPR017926]	0.3815971691190313	0.2071887514669332	0.8358624517497706	1.0	1.0	4	P17812,Q9NRF8	2
+Peptidase C2, calpain, catalytic domain [IPR001300]	0.602244389027437	0.2028675208176775	0.8392385810232705	1.0	1.0	2	P17655	1
+Peptidase C2, calpain, large subunit, domain III [IPR022682]	0.602244389027437	0.2028675208176775	0.8392385810232705	1.0	1.0	2	P17655	1
+Calpain subdomain III [IPR033883]	0.602244389027437	0.2028675208176775	0.8392385810232705	1.0	1.0	2	P17655	1
+Peptidase C2, calpain, domain III [IPR022683]	0.602244389027437	0.2028675208176775	0.8392385810232705	1.0	1.0	2	P17655	1
+RNA polymerase, N-terminal [IPR006592]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	1.0	3	O14802,P24928	2
+RNA polymerase Rpb1, domain 1 [IPR007080]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	1.0	3	O14802,P24928	2
+RNA polymerase, alpha subunit [IPR000722]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	1.0	3	O14802,P24928	2
+RNA polymerase Rpb1, domain 5 [IPR007081]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	1.0	3	O14802,P24928	2
+RNA polymerase Rpb1, domain 3 [IPR007066]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	1.0	3	O14802,P24928	2
+RNA polymerase Rpb1, domain 4 [IPR007083]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	1.0	3	O14802,P24928	2
+MIF4G-like, type 3 [IPR003890]	0.3582293197053008	0.1649915205009882	0.8689506562485827	1.0	1.0	7	Q09161	1
+VHS domain [IPR002014]	0.5782418952618515	0.1623296629303626	0.8710462568159352	1.0	1.0	2	O14964	1
+GRAM domain [IPR004182]	0.5735660847880362	0.1551352240546418	0.8767147135510456	1.0	1.0	2	Q66K14	1
+Translation initiation factor, beta propellor-like domain [IPR013979]	0.3505926388022483	0.1420197338433113	0.8870644183262215	1.0	1.0	4	Q9NV06,Q9BY44,P55884	3
+SUI1 domain [IPR001950]	0.5620324189526249	0.1383661160676828	0.8899510748554678	1.0	1.0	2	P41214	1
+Band 4.1, C-terminal [IPR008379]	0.3991269098846228	0.124301204876982	0.9010767933474044	1.0	1.0	3	Q9Y2J2,O43491	2
+SAB domain [IPR007477]	0.3991269098846228	0.124301204876982	0.9010767933474044	1.0	1.0	3	Q9Y2J2,O43491	2
+Phox homology [IPR001683]	0.3509729358625438	0.1145265771505602	0.9088203794834112	1.0	1.0	10	Q9Y2I1	1
+OBG-type guanine nucleotide-binding (G) domain [IPR031167]	0.3329173166926619	0.1122817886171366	0.9105999810638532	1.0	1.0	5	P55039,A4D1E9,Q9NTK5,Q9BZE4	4
+TGS [IPR004095]	0.3330212234706599	0.1040061704633168	0.9171644518088808	1.0	1.0	6	P26639,Q9NTK5,Q9BW92,P55039,Q9NYK5	5
+Ubiquitin-associated domain [IPR015940]	0.3703056636008001	0.1014715800800265	0.9191761169021562	1.0	1.0	17	Q9Y5A7,Q5T6F2,Q9UPU5	3
+Helicase-associated domain [IPR007502]	0.3513593904266081	0.0887001975419654	0.929320175540116	1.0	1.0	13	O60231,Q9H2U1,Q7Z478	3
+Domain of unknown function DUF1605 [IPR011709]	0.3513593904266081	0.0887001975419654	0.929320175540116	1.0	1.0	13	O60231,Q9H2U1,Q7Z478	3
+Class I myosin, motor domain [IPR036072]	0.3162819713038095	0.0883037253084352	0.9296352781564656	1.0	1.0	4	Q12965,O94832,O43795	3
+Class I myosin tail homology domain [IPR010926]	0.3162819713038095	0.0883037253084352	0.9296352781564656	1.0	1.0	4	Q12965,O94832,O43795	3
+Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]	0.3147223955084266	0.0863102774715406	0.9312197687248353	1.0	1.0	4	Q15046,O43776,Q6PI48	3
+OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]	0.3148205928237069	0.0791549678590535	0.9369093625949964	1.0	1.0	5	Q15046,O43776,P27694,Q6PI48	4
+CoA-binding [IPR003781]	0.5077930174563666	0.0775117565360872	0.938216439048958	1.0	1.0	2	P53597	1
+Extended synaptotagmin, C2B domain [IPR037749]	0.5028054862842968	0.073317060329807	0.9415538160556756	1.0	1.0	2	A0FGR8	1
+Synaptotagmin, SMP domain [IPR039010]	0.5028054862842968	0.073317060329807	0.9415538160556756	1.0	1.0	2	A0FGR8	1
+Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]	0.5028054862842968	0.073317060329807	0.9415538160556756	1.0	1.0	2	A0FGR8	1
+Extended synaptotagmin, C2A domain [IPR037733]	0.5028054862842968	0.073317060329807	0.9415538160556756	1.0	1.0	2	A0FGR8	1
+Extended synaptotagmin, C-terminal C2 domain [IPR037752]	0.5028054862842968	0.073317060329807	0.9415538160556756	1.0	1.0	2	A0FGR8	1
+DNA ligase, ATP-dependent, central [IPR012310]	0.496882793017464	0.0686173453280284	0.9452942118332366	1.0	1.0	2	P49916	1
+DNA ligase, ATP-dependent, C-terminal [IPR012309]	0.496882793017464	0.0686173453280284	0.9452942118332366	1.0	1.0	2	P49916	1
+DNA ligase, ATP-dependent, N-terminal [IPR012308]	0.496882793017464	0.0686173453280284	0.9452942118332366	1.0	1.0	2	P49916	1
+Citron homology (CNH) domain [IPR001180]	0.3429996881820991	0.0651344832206193	0.9480669250755484	1.0	1.0	3	Q8WUH2,Q9Y5S2	2
+Potassium channel tetramerisation-type BTB domain [IPR003131]	0.4912718204488856	0.0644391319527234	0.9486205719658414	1.0	1.0	2	Q9NXV2	1
+STAG [IPR013721]	0.4906483790523769	0.0639909958084785	0.9489773964184522	1.0	1.0	2	Q8N3U4	1
+Stromalin conservative domain [IPR020839]	0.4906483790523769	0.0639909958084785	0.9489773964184522	1.0	1.0	2	Q8N3U4	1
+WSTF/Acf1/Cbp146 [IPR013136]	0.4756857855361675	0.054163274522532	0.9568050803979766	1.0	1.0	2	Q9UIG0	1
+Ubiquitin conjugation factor E4, core [IPR019474]	0.4716334164588608	0.0517956678211842	0.9586915074976874	1.0	1.0	2	Q14139	1
+Diaphanous autoregulatory (DAD) domain [IPR014767]	0.3189897100093559	0.0500866473532169	0.960053340251789	1.0	1.0	3	O60610,O60879	2
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.4616583541147213	0.0464672565604221	0.9629378313630051	1.0	1.0	2	Q9NVI7	1
+Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]	0.4557356608478873	0.0436232044405321	0.9652047548329328	1.0	1.0	2	Q13555	1
+Methyltransferase type 11 [IPR013216]	0.4529301745635993	0.0423550928395536	0.9662156269217408	1.0	1.0	2	Q8N6R0	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.313371263481989	0.0418037614854536	0.9666551364042744	1.0	1.0	8	O00429,O60313,Q8IWA4,Q9H4M9	4
+Dynamin, N-terminal [IPR045063]	0.313371263481989	0.0418037614854536	0.9666551364042744	1.0	1.0	8	O00429,O60313,Q8IWA4,Q9H4M9	4
+F-box domain [IPR001810]	0.2651278852152285	0.0409851291835564	0.9673077510934712	1.0	1.0	4	Q13309,Q14241,Q8NEZ5	3
+Gamma-adaptin ear (GAE) domain [IPR008153]	0.4451371571072405	0.0390870209515702	0.9688210088425816	1.0	1.0	2	Q9UJY4	1
+Phosducin, thioredoxin-like domain [IPR024253]	0.4376558603491359	0.0362831163708307	0.9710566122597626	1.0	1.0	2	Q13371	1
+Coatomer, WD associated region [IPR006692]	0.4332917705735721	0.0347892145341327	0.9722478209818786	1.0	1.0	2	P35606	1
+Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]	0.2759588400374251	0.0344342386756768	0.9725308811375076	1.0	1.0	3	P23193,Q14241	2
+Ribosomal protein S5, C-terminal [IPR005324]	0.420511221945146	0.0309667651685853	0.9752960445078218	1.0	1.0	2	P15880	1
+Ribosomal protein S5, N-terminal [IPR013810]	0.420511221945146	0.0309667651685853	0.9752960445078218	1.0	1.0	2	P15880	1
+IMP dehydrogenase/GMP reductase [IPR001093]	0.4142768079800564	0.0293767818097705	0.9765640902430814	1.0	1.0	2	P20839	1
+MoaB/Mog domain [IPR001453]	0.4071072319202087	0.0277493669230825	0.9778620497343908	1.0	1.0	2	Q9NQX3	1
+Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]	0.4018079800498846	0.0266744796890961	0.9787193681456396	1.0	1.0	2	P07814	1
+Thioredoxin-like fold [IPR012336]	0.3943266832917774	0.0253268619448517	0.9797942480667544	1.0	1.0	2	Q6DKJ4	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.3912094763092341	0.0248199649631539	0.9801985662254904	1.0	1.0	2	P35611	1
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.3852867830424009	0.0239387199754955	0.9809014890497352	1.0	1.0	2	P54725	1
+XPC-binding domain [IPR015360]	0.3852867830424009	0.0239387199754955	0.9809014890497352	1.0	1.0	2	P54725	1
+Spermidine synthase, tetramerisation domain [IPR035246]	0.3706359102244463	0.0221689983030898	0.9823131472806944	1.0	1.0	2	P52788	1
+Polyamine biosynthesis  domain [IPR030374]	0.3706359102244463	0.0221689983030898	0.9823131472806944	1.0	1.0	2	P52788	1
+ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]	0.3690773067331747	0.0220113450845325	0.982438905662352	1.0	1.0	2	Q15477	1
+rRNA-processing arch domain [IPR025696]	0.3690773067331747	0.0220113450845325	0.982438905662352	1.0	1.0	2	Q15477	1
+PTB/PI domain [IPR006020]	0.2701160926463196	0.0217554758161707	0.9826430109234174	1.0	1.0	5	Q9Y3P9,Q9UKG1	2
+PABP, RNA recognition motif 2 [IPR045305]	0.3313591022443969	0.0195248834360548	0.9844223867135932	1.0	1.0	2	P11940	1
+Rap/Ran-GAP domain [IPR000331]	0.3266832917705815	0.0193513956874556	0.9845607837609875	1.0	1.0	2	Q86X10	1
+EGF-like calcium-binding domain [IPR001881]	0.3151496259351704	0.0190091650528361	0.9848337940766853	1.0	1.0	2	O94813	1
+SANT domain [IPR017884]	0.311215889725988	0.0172858648290274	0.9862085621523996	1.0	1.0	11	Q99543	1
+Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]	0.3268154783897024	0.007789930673479	0.993784597447536	1.0	1.0	17	Q9UPU5	1
+Ubiquitin specific protease domain [IPR028889]	0.3268154783897024	0.007789930673479	0.993784597447536	1.0	1.0	17	Q9UPU5	1
+Myb domain [IPR017930]	0.3001983290687366	0.0041247615232	0.9967089257958492	1.0	1.0	10	Q99543	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Proteasome, subunit alpha/beta [IPR001353]", "1": "Mitochondrial carrier protein [IPR002067]"}

interpro_family/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:90ca21c7a147ba1233cc3b55e748b5b1a627344c90d630ba9019d7f06ee5a30b
+size 148870

interpro_family/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]	2	6	2.381598188573668	0.0172376946552343	2.121359223300971	5.466019417475728	1.4317001483019938	0.1783942022754649	1.021530403905949	0.5881604361499402	0.986353205880356	0.2226891741813114	1.0	0.0378187125466048	4.800413077288208e-05	0.0007187465088185	0.0053031795330487
+Proteasome B-type subunit [IPR023333]	4	7	2.101682335619821	0.0355811119651543	3.699029126213592	6.970873786407767	1.6670727234653664	0.1509307531330224	1.4503762582219135	0.1681602725795027	0.9611878160538336	0.233503072382129	1.0	1.0	0.0032139762811053	0.0010588751859522	2.8311070051942505e-05

interpro_family/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3210,
+    "annotations_size": 2482,
+    "title": "Average number of proteins per term",
+    "value": 1.2723609991941982
+}

interpro_family/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C408/C408_val_log2fc"}

interpro_family/result.tsv

@@ -0,0 +1,106 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]	0.8599613981089556	2.381598188573668	0.0172376946552343	1.0	0.5290772631882599	6	P09960,P55786	2
+Aminopeptidase N-type [IPR034016]	0.8863738603534785	2.1938918561422605	0.0282431850047832	1.0	0.5290772631882599	4	P55786	1
+Nucleosome assembly protein (NAP) [IPR002164]	0.8814722395508441	2.174004574872237	0.0297047916277755	1.0	0.5290772631882599	4	Q01105,P55209,Q99733	3
+Proteasome B-type subunit [IPR023333]	0.7999387565809215	2.101682335619821	0.0355811119651543	1.0	0.5290772631882599	7	P28070,P28074,P28072,P49721	4
+Major facilitator superfamily [IPR011701]	0.8601668188168234	2.087100705124643	0.0368790323501031	1.0	0.5290772631882599	4	P53985,Q7L0J3	2
+Eukaryotic porin/Tom40 [IPR027246]	0.8578379060757381	2.077556169336544	0.0377502567260275	1.0	0.5290772631882599	4	P45880	1
+Transmembrane protein GPR107/GPR108-like [IPR009637]	0.9794200187090734	2.057184159678566	0.0396685146554243	1.0	0.5290772631882599	3	Q8NBN3,Q9NPR9	2
+P-type ATPase [IPR001757]	0.7419707124042778	1.8640111856387505	0.0623201335438758	1.0	0.5290772631882599	6	Q9HD20,P23634	2
+Peptidase S10, serine carboxypeptidase [IPR001563]	0.909260991580924	1.7955591317482569	0.0725646604937597	1.0	0.5290772631882599	3	Q9HB40,P10619	2
+Histidine phosphatase superfamily, clade-2 [IPR000560]	0.9069616787967596	1.786896254111035	0.0739542580636221	1.0	0.5290772631882599	3	Q9NPH0	1
+Porin, eukaryotic type [IPR001925]	0.903177312303544	1.772627198736933	0.0762905017256585	1.0	0.5290772631882599	3	P45880	1
+Type 1 protein exporter [IPR039421]	0.7375360446202424	1.6996516594622582	0.0891964671324019	1.0	0.529896962429788	5	O75027,Q03518,P08183	3
+Nucleobindin [IPR040250]	0.9928304239401496	1.4092678668491054	0.1587559765954287	1.0	0.5846948911461681	2	Q02818	1
+CD36 family [IPR002159]	0.9918952618453868	1.405876428372176	0.1597608218992534	1.0	0.5850402345038459	2	Q14108	1
+Haem oxygenase [IPR002051]	0.9841022443890276	1.3776211481052816	0.1683202880347833	1.0	0.5917435621846067	2	P30519	1
+Haem oxygenase-like [IPR016053]	0.9841022443890276	1.3776211481052816	0.1683202880347833	1.0	0.5917435621846067	2	P30519	1
+Mitochondrial carrier UCP-like [IPR002030]	0.9753740648379056	1.3459939188272825	0.1783044777738509	1.0	0.603754043430693	2	Q9H2D1	1
+Mini-chromosome maintenance protein [IPR031327]	0.6254561243151125	1.3266987869815643	0.1846083423980733	1.0	0.6121787758751543	6	Q14566,P33993,P33992	3
+Peptidase T1A, proteasome beta-subunit [IPR000243]	0.7798565637667643	1.3022780620720869	0.1928213482522003	1.0	0.6210302436982256	3	P28072,P28074	2
+TAF15/EWS/TLS family [IPR034870]	0.7795447458684153	1.3010827084399894	0.1932301458338101	1.0	0.6210693176272348	3	P35637,Q01844	2
+Proteasome, subunit alpha/beta [IPR001353]	0.6525184655777766	1.2964737253815777	0.194812326501462	1.0	0.6217254608969961	14	P25787,P28074,P60900,P28072,P28070,P20618,P49721	7
+V-type  ATPase, V0 complex, 116kDa subunit family [IPR002490]	0.9569825436408984	1.2794483523074272	0.2007392160701944	1.0	0.6226544058865167	2	Q93050	1
+ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]	0.9569825436408984	1.2794483523074272	0.2007392160701944	1.0	0.6226544058865167	2	Q93050	1
+HnRNP-L/PTB [IPR006536]	0.6621045261158889	1.2504391509481554	0.2111391703234093	1.0	0.6339167976488856	4	P14866,Q8WVV9	2
+Ergosterol biosynthesis ERG4/ERG24 [IPR001171]	0.9470074812967588	1.2434325900860053	0.2137084670798019	1.0	0.6339167976488856	2	Q14739	1
+Cytochrome P450 [IPR001128]	0.9417082294264336	1.2243271459229834	0.2208288404095808	1.0	0.6417428788006884	2	Q6UW02	1
+Peroxisomal acyl-coenzyme A oxidase [IPR034171]	0.9407730673316708	1.2209578281710969	0.2221019874656693	1.0	0.6417428788006884	2	Q15067	1
+Acyl-CoA oxidase [IPR012258]	0.9407730673316708	1.2209578281710969	0.2221019874656693	1.0	0.6417428788006884	2	Q15067	1
+Tricarboxylate/iron carrier [IPR004686]	0.7533288490613467	1.2006832834465062	0.2298740809935324	1.0	0.6518027477103471	3	Q96NB2	1
+Amyloidogenic glycoprotein [IPR008155]	0.9320448877805492	1.1895461954406328	0.23422480400622	1.0	0.6567840414554948	2	P05067	1
+Cleft lip and palate transmembrane protein 1-like protein [IPR030434]	0.9258104738154618	1.1671521099833604	0.2431489468579302	1.0	0.6610029420606601	2	O96005	1
+Cleft lip and palate transmembrane 1 [IPR008429]	0.9258104738154618	1.1671521099833604	0.2431489468579302	1.0	0.6610029420606601	2	O96005	1
+Fragile X mental retardation syndrome-related protein [IPR040148]	0.7290302463361419	1.1079765707840752	0.2678719344803792	1.0	0.6843382056043488	3	P51116,Q06787	2
+Tropomyosin [IPR000533]	0.7261115667986184	1.0968767744769956	0.272695262865045	1.0	0.6934729942941	3	P09493	1
+Clathrin adaptor, mu subunit [IPR001392]	0.7019020891799277	1.0052260380307512	0.3147880199925632	1.0	0.7229954961723339	3	Q9BXS5,Q9Y2T2	2
+Membrane bound O-acyl transferase, MBOAT [IPR004299]	0.8731296758104751	0.9799350201169156	0.3271181949803483	1.0	0.7322779219155694	2	P35610	1
+Nonaspanin (TM9SF) [IPR004240]	0.8728179551122215	0.9788409940313992	0.327658550902743	1.0	0.7326563273338812	2	Q9HD45	1
+Oligosaccharyl transferase, STT3 subunit [IPR003674]	0.872506234413966	0.9777471652810464	0.3281993881666303	1.0	0.7329956624631256	2	P46977	1
+HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]	0.6831930152790906	0.935060901639399	0.3497569144987089	1.0	0.7537976026418207	3	Q9H857,P49902	2
+Prenyltransferase subunit beta [IPR045089]	0.8385286783042409	0.8598589474557794	0.3898668005294787	1.0	0.7927264690221306	2	P49356	1
+Ribosomal protein L15 [IPR030878]	0.8304239401496276	0.8321902390559153	0.4053015725575632	1.0	0.8019782108214061	2	P46776	1
+DNA mismatch repair MutS family [IPR045076]	0.6545057686311151	0.8290520715913391	0.4070749427289941	1.0	0.8019782108214061	3	P20585,P43246	2
+A-kinase anchoring protein 95 (AKAP95) [IPR007071]	0.6526299046584018	0.822201610716475	0.410962162209235	1.0	0.8025030476629407	3	O43823	1
+Ribosomal protein S11 [IPR001971]	0.8216957605985057	0.8026204390614207	0.4221941510491132	1.0	0.8094029969928576	2	P62263	1
+Translation initiation factor IF2/IF5 [IPR045196]	0.8201371571072337	0.7973663030366798	0.4252383235790038	1.0	0.8112540500561779	2	P55010	1
+Gamma-tubulin complex component protein [IPR007259]	0.8126558603491291	0.7722627227418716	0.4399588390314484	1.0	0.8227138173669986	2	Q96CW5	1
+HnRNP R/Q splicing factor [IPR006535]	0.8114089775561117	0.7680980573555098	0.442428930964301	1.0	0.8227138173669986	2	O43390	1
+ABC transporter Tap-like [IPR013305]	0.8110972568578574	0.7670577730414051	0.4430471668239724	1.0	0.8227138173669986	2	Q03518	1
+Microtubule-associated protein RP/EB [IPR027328]	0.8026807980049897	0.7391072028393683	0.4598419034316137	1.0	0.8343038043254862	2	Q15555	1
+Purine 5'-nucleotidase [IPR016695]	0.7973815461346657	0.7216496456546435	0.4705099079826822	1.0	0.8410224648422258	2	Q9H857	1
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]	0.7942643391521221	0.7114337071100657	0.4768155175680628	1.0	0.8435182570234725	2	Q9H2H8	1
+Phosphatidyl serine synthase [IPR004277]	0.793329177057359	0.7083768026397346	0.4787112940577673	1.0	0.8445273071903485	2	P48651	1
+Protein arginine N-methyltransferase [IPR025799]	0.5123890236640387	0.7071722263116282	0.4794594559774265	1.0	0.8445273071903485	5	Q6P2P2,Q86X55,O14744	3
+E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]	0.7861596009975087	0.6850648854047008	0.4933029773267072	1.0	0.8526309120646849	2	Q14669	1
+MICOS complex subunit MIC26/MIC27 [IPR019166]	0.7811720698254389	0.6689820674719213	0.5035069172128128	1.0	0.8598213207960974	2	Q9BUR5	1
+MICOS complex subunit MIC26/MIC27, animal [IPR033182]	0.7811720698254389	0.6689820674719213	0.5035069172128128	1.0	0.8598213207960974	2	Q9BUR5	1
+Exportin 4/7-like [IPR044189]	0.7805486284289302	0.6669797072484127	0.5047850955860991	1.0	0.8598213207960974	2	Q9UIA9	1
+Derlin [IPR007599]	0.7711970074812999	0.6371654307553906	0.5240170924735599	1.0	0.8758319350298827	2	Q9GZP9	1
+Peroxysomal long chain fatty acyl transporter [IPR005283]	0.7671446384039928	0.6243791106042085	0.5323786404794411	1.0	0.8787183714699042	2	P28288	1
+CPSF6/7 family [IPR034772]	0.7528054862842922	0.579825451656914	0.5620323321560479	1.0	0.9069988611256896	2	Q16630	1
+Cyclin [IPR039361]	0.7512468827930205	0.5750505174692684	0.5652571320252342	1.0	0.9080700334541302	2	O95067	1
+Copine [IPR045052]	0.5807330287311574	0.5706418482130275	0.5682424450779577	1.0	0.9089711140669404	3	O75131	1
+Dynamin [IPR022812]	0.4881472239550747	0.5361977608643386	0.5918218808688347	1.0	0.9219790963593276	4	O60313,P50570,O00429	3
+Peptidase M3A/M3B [IPR045090]	0.5665731212971561	0.5244184437171966	0.5999875310997262	1.0	0.924375575536636	3	Q99797,P52888	2
+Prefoldin alpha-like [IPR004127]	0.7294264339152157	0.5097180324032082	0.6102490179150721	1.0	0.929093743061358	2	Q99471	1
+CTP synthase [IPR004468]	0.7166458852867869	0.4728679632727187	0.6363073825048742	1.0	0.9378354651883002	2	P17812	1
+Kinesin light chain [IPR002151]	0.6901496259351664	0.4002112937046898	0.6890008970323542	1.0	0.965067847874889	2	Q07866	1
+Translin family [IPR002848]	0.6836034912718247	0.3831011302485824	0.7016447816294153	1.0	0.9724111067845168	2	Q15631	1
+Protein PRRC2 [IPR033184]	0.5070159027128031	0.3473586766816398	0.7283218740454496	1.0	0.9832434440653498	3	Q9Y520,Q5JSZ5	2
+Proteasome alpha-type subunit [IPR023332]	0.4103843524875124	0.3439633423276831	0.7308738544782276	1.0	0.9832434440653498	7	P60900	1
+DnaJ homolog subfamily A member 1/2-like [IPR044713]	0.6589775561097304	0.3219873631831754	0.7474622678646863	1.0	0.9836466972193864	2	O60884	1
+Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]	0.6536783042394064	0.3095415245849245	0.7569096299928293	1.0	0.9836466972193864	2	Q2NL82	1
+SCAMP [IPR007273]	0.6474438902743194	0.2952331112174521	0.7678158095840264	1.0	0.9836466972193864	2	O15127	1
+Dedicator of cytokinesis [IPR026791]	0.6424563591022494	0.2840507387809158	0.7763714973769851	1.0	0.9836466972193864	2	Q14185	1
+Glutathione Transferase family [IPR040079]	0.3824020457422701	0.2188527183604338	0.8267647788448182	1.0	0.9836466972193864	9	Q13505	1
+RNA (C5-cytosine) methyltransferase [IPR023267]	0.4483941378235004	0.2083743548865318	0.8349366786766312	1.0	0.9836466972193864	3	Q96P11,P46087	2
+Peptidase C2, calpain family [IPR022684]	0.602244389027437	0.2028675208176775	0.8392385810232705	1.0	0.9836466972193864	2	P17655	1
+DNA-directed RNA polymerase, subunit beta-prime [IPR045867]	0.4437168693482998	0.1990598218271393	0.8422159497601149	1.0	0.9836466972193864	3	O14802,P24928	2
+Importin beta family [IPR040122]	0.3636297903597258	0.1926143543687608	0.8472610022816247	1.0	0.9836466972193864	6	O60518,Q92973	2
+Sec1-like protein [IPR001619]	0.3659906396255807	0.1880446205825211	0.8508416728863157	1.0	0.9836466972193864	5	Q9H267,Q96AX1,O00186,Q8WU76	4
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]	0.4150427377323739	0.1480573773160447	0.8822974866120641	1.0	0.9836466972193864	3	Q9H2H8	1
+Enoyl-CoA hydratase/isomerase [IPR001753]	0.3442461468161068	0.124703806799124	0.9007580435403216	1.0	0.9836466972193864	7	Q08426,Q13011	2
+Dephospho-CoA kinase [IPR001977]	0.5470698254364156	0.1186638059868404	0.9055417125238984	1.0	0.9836466972193864	2	Q13057	1
+Small GTPase Rho [IPR003578]	0.3272557993585402	0.1012810718859066	0.9193273413697732	1.0	0.9836466972193864	5	P63000,P61586	2
+Mitochondrial carrier protein [IPR002067]	0.3424015009380848	0.075419824243468	0.9398806866637668	1.0	0.9836466972193864	12	Q9UJS0,P05141,O43808,Q9H936,Q9BQT8,Q8TBP6,O75746,P12235,P12236,Q9HC21,Q6NUK1	11
+Glycosyl transferase, family 8 [IPR002495]	0.5000000000000075	0.0710532688589168	0.9433553601647512	1.0	0.9836466972193864	2	P46976	1
+DNA ligase, ATP-dependent [IPR000977]	0.496882793017464	0.0686173453280284	0.9452942118332366	1.0	0.9836466972193864	2	P49916	1
+Ribosomal protein L24e-related [IPR000988]	0.4940773067331739	0.0664954097606445	0.9469834121036512	1.0	0.9836466972193864	2	Q9UHA3	1
+Cohesin subunit Scc3/SA [IPR039662]	0.4906483790523769	0.0639909958084785	0.9489773964184522	1.0	0.9836466972193864	2	Q8N3U4	1
+FAM98 [IPR018797]	0.4791147132169655	0.0562620674941323	0.9551330367009434	1.0	0.9841062978420324	2	Q8NCA5	1
+GrpE nucleotide exchange factor [IPR000740]	0.4763092269326739	0.0545382970893375	0.9565062973135808	1.0	0.9841062978420324	2	Q8TAA5	1
+Ubiquitin conjugation factor E4 [IPR045132]	0.4716334164588608	0.0517956678211842	0.9586915074976874	1.0	0.9841062978420324	2	Q14139	1
+Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]	0.314624259432492	0.0478980935941856	0.9617974587401504	1.0	0.9844254059008976	3	O43776,Q6PI48	2
+ATPase family AAA domain-containing protein 3 [IPR039188]	0.4616583541147213	0.0464672565604221	0.9629378313630051	1.0	0.9847596610807496	2	Q9NVI7	1
+tRNA methyltransferase, Trm1 [IPR002905]	0.4488778054862927	0.0406099302136863	0.9676068675229555	1.0	0.9855280815232698	2	Q7Z2T5	1
+Ribosomal protein S5 [IPR000851]	0.420511221945146	0.0309667651685853	0.9752960445078218	1.0	0.9890977223758092	2	P15880	1
+Sorting nexin-5/6/32 [IPR014637]	0.4192643391521274	0.0306351174250615	0.9755605356299348	1.0	0.9890977223758092	2	Q9UNH7	1
+Branched-chain amino acid aminotransferase II [IPR005786]	0.4173940149626015	0.0301505990375877	0.975946946856711	1.0	0.9890977223758092	2	P54687	1
+Branched-chain aminotransferase [IPR033939]	0.4173940149626015	0.0301505990375877	0.975946946856711	1.0	0.9890977223758092	2	P54687	1
+Aminotransferase class IV [IPR001544]	0.4173940149626015	0.0301505990375877	0.975946946856711	1.0	0.9890977223758092	2	P54687	1
+Inosine-5'-monophosphate dehydrogenase [IPR005990]	0.4142768079800564	0.0293767818097705	0.9765640902430814	1.0	0.9892010699413352	2	P20839	1
+UV excision repair protein Rad23 [IPR004806]	0.3852867830424009	0.0239387199754955	0.9809014890497352	1.0	0.9916894076665754	2	P54725	1
+ATP-dependent RNA helicase Ski2-like [IPR016438]	0.3690773067331747	0.0220113450845325	0.982438905662352	1.0	0.9924352315237924	2	Q15477	1
+Sodium/potassium-transporting ATPase subunit beta [IPR000402]	0.3425810473815538	0.0200412061575698	0.9840105013977092	1.0	0.9926005084477196	2	P54709	1
+Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]	0.3313591022443969	0.0195248834360548	0.9844223867135932	1.0	0.9926005084477196	2	P11940	1

interpro_homologous_superfamily/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_homologous_superfamily/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Glycoside hydrolase superfamily [IPR017853]", "1": "Mitochondrial carrier domain superfamily [IPR023395]", "2": "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "3": "Nucleophile aminohydrolases, N-terminal [IPR029055]", "4": "Galactose-binding-like domain superfamily [IPR008979]", "5": "HAD-like superfamily [IPR036412]", "6": "HAD superfamily [IPR023214]", "7": "Alpha/Beta hydrolase fold [IPR029058]", "8": "FAD/NAD(P)-binding domain superfamily [IPR036188]", "9": "TGS-like [IPR012676]", "10": "Beta-grasp domain superfamily [IPR012675]"}