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- interpro_active_site/advanced/idx2term.json +1 -0
- interpro_active_site/basic/idx2term.json +1 -0
- interpro_active_site/basic/plot_0.png +3 -0
- interpro_active_site/consensus.joblib +3 -0
- interpro_active_site/df_merge.tsv +1 -0
- interpro_active_site/metrics.json +7 -0
- interpro_active_site/paths.json +1 -0
- interpro_active_site/result.tsv +9 -0
- interpro_active_site/selections.json +1 -0
- interpro_binding_site/advanced/idx2term.json +1 -0
- interpro_binding_site/basic/idx2term.json +1 -0
- interpro_binding_site/basic/plot_0.png +3 -0
- interpro_binding_site/consensus.joblib +3 -0
- interpro_binding_site/df_merge.tsv +1 -0
- interpro_binding_site/metrics.json +7 -0
- interpro_binding_site/paths.json +1 -0
- interpro_binding_site/result.tsv +4 -0
- interpro_binding_site/selections.json +1 -0
- interpro_conserved_site/advanced/idx2term.json +1 -0
- interpro_conserved_site/basic/idx2term.json +1 -0
- interpro_conserved_site/basic/plot_0.png +3 -0
- interpro_conserved_site/basic/plot_1.png +3 -0
- interpro_conserved_site/basic/plot_2.png +3 -0
- interpro_conserved_site/consensus.joblib +3 -0
- interpro_conserved_site/df_merge.tsv +1 -0
- interpro_conserved_site/metrics.json +7 -0
- interpro_conserved_site/paths.json +1 -0
- interpro_conserved_site/result.tsv +42 -0
- interpro_conserved_site/selections.json +1 -0
- interpro_domain/advanced/idx2term.json +1 -0
- interpro_domain/basic/idx2term.json +1 -0
- interpro_domain/basic/plot_0.png +3 -0
- interpro_domain/basic/plot_1.png +3 -0
- interpro_domain/basic/plot_10.png +3 -0
- interpro_domain/basic/plot_11.png +3 -0
- interpro_domain/basic/plot_12.png +3 -0
- interpro_domain/basic/plot_13.png +3 -0
- interpro_domain/basic/plot_14.png +3 -0
- interpro_domain/basic/plot_15.png +3 -0
- interpro_domain/basic/plot_16.png +3 -0
- interpro_domain/basic/plot_2.png +3 -0
- interpro_domain/basic/plot_3.png +3 -0
- interpro_domain/basic/plot_4.png +3 -0
- interpro_domain/basic/plot_5.png +3 -0
- interpro_domain/basic/plot_6.png +3 -0
- interpro_domain/basic/plot_7.png +3 -0
- interpro_domain/basic/plot_8.png +3 -0
- interpro_domain/basic/plot_9.png +3 -0
- interpro_domain/consensus.joblib +3 -0
- interpro_domain/df_merge.tsv +3 -0
interpro_active_site/advanced/idx2term.json
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{}
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interpro_active_site/basic/idx2term.json
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{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
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interpro_active_site/basic/plot_0.png
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Git LFS Details
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interpro_active_site/consensus.joblib
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oid sha256:1f487467bbb198b792d899c5fa4e54a0344fe481e6dcdbcf369ead1ebe015209
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size 75860
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interpro_active_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_active_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3210,
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"annotations_size": 53,
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"title": "Average number of proteins per term",
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"value": 2.830188679245283
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}
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interpro_active_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C409/C409_val_log2fc"}
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interpro_active_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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ATP:guanido phosphotransferase active site [IPR022415] 0.8114089775561117 1.4781607937239114 0.1393647451188435 0.999648913588897 0.3887542890157215 2 P12532 1
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Serine/threonine-protein kinase, active site [IPR008271] 0.3078290296994877 0.9689817681156068 0.3325542858526202 0.9999999995056378 0.6294777553638884 53 Q86Y07,P06493,O14757,P28482,P19525,Q7KZI7,P11802,O15111,O43318,Q99640,O14976,Q9H4A3,Q9Y6R4,O00311,P49840,O96017,Q14004,Q9NYV4,P49841,P78362,Q00534,Q96KB5,Q9UL54,P53350 24
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ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.5826059850374127 0.5043483769865547 0.6140165876378934 1.0 0.7568111429025197 2 P53597 1
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Peptidase family C14A, His active site [IPR016129] 0.5473610887388074 0.2564467419494981 0.797605899358103 1.0 0.8887404998191512 3 P42575 1
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Peptidase family C14A, cysteine active site [IPR033139] 0.5473610887388074 0.2564467419494981 0.797605899358103 1.0 0.8887404998191512 3 P42575 1
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Protein-tyrosine phosphatase, active site [IPR016130] 0.4378445179837574 0.2470144301157192 0.804897056439986 1.0 0.8887404998191512 5 Q06124,O75319 2
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Cysteine peptidase, cysteine active site [IPR000169] 0.3754287496102176 0.0305789152483492 0.9756053574797756 1.0 0.9760681701666538 3 P07384,P17655 2
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Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999] 0.3740560276462231 0.0299985994244389 0.9760681701666538 1.0 0.9760681701666538 3 P00390 1
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interpro_active_site/selections.json
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{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP2", "CASP3", "CASP6", "CDC42BPB", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP11", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MARK3", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN2", "PLK1", "PREP", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RIPK1", "RNGTT", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK2", "TIGAR", "TOP1", "TOP3A", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["CAPN1", "CAPN2", "CASP2", "CDC7", "CDK1", "CDK12", "CDK13", "CDK4", "CDK6", "CHEK1", "CHEK2", "CHUK", "CKMT1A*", "DUSP11", "EIF2AK2", "GAK", "GSK3A", "GSK3B", "GSR", "MAP3K4", "MAP3K7", "MAPK1", "MARK2", "PBK", "PKMYT1", "PLK1", "PTPN11", "SRPK2", "SUCLG1", "TAOK2", "VRK2", "WNK1"]}
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interpro_binding_site/advanced/idx2term.json
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{}
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interpro_binding_site/basic/idx2term.json
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{"0": "Protein kinase, ATP binding site [IPR017441]"}
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interpro_binding_site/basic/plot_0.png
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interpro_binding_site/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:f6be79e838b65a176dbaaf9a21332fca825fa6c3f1345c903749e3ee7ab858ac
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size 75104
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interpro_binding_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_binding_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3210,
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"annotations_size": 31,
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"title": "Average number of proteins per term",
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"value": 4.870967741935484
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}
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interpro_binding_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C409/C409_val_log2fc"}
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interpro_binding_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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Protein kinase, ATP binding site [IPR017441] 0.3457377972250771 1.4248390534855766 0.1542037304366759 0.9944379008631332 0.2811950378551149 53 P06493,O14757,P28482,Q7KZI7,P11802,O15111,O43318,Q99640,Q9P289,Q9Y6R4,O00311,P49840,Q16539,Q14004,Q9NYV4,P49841,P78362,Q00534,Q13043,Q8TF76,Q9UL54,P53350 22
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Peptidase M16, zinc-binding site [IPR001431] 0.5612339670917224 0.665170537330705 0.5059414226625052 0.9999999996785364 0.6032378500976023 5 Q10713,P22695,P14735 3
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PPM-type phosphatase, divalent cation binding [IPR000222] 0.5748129675810538 0.4765121461459561 0.6337095562031005 0.99999999999997 0.6635432219036059 2 Q9H0C8 1
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interpro_binding_site/selections.json
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{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "ARG2", "AURKA", "AURKB", "BPNT1", "CALU", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK6", "CHEK1", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HASPIN", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP3K4", "MAP3K7", "MAP4K4", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MARK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1G", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK3", "STK4", "TAOK2", "TKT", "TTK", "TUBB", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CDC7", "CDK1", "CDK12", "CDK13", "CDK4", "CDK6", "CHEK1", "CHUK", "GSK3A", "GSK3B", "HASPIN", "IDE", "ILKAP", "MAP3K4", "MAP3K7", "MAPK1", "MAPK14", "MARK2", "PKMYT1", "PLK1", "PMPCA", "SRPK2", "STK26", "STK4", "TAOK2", "UQCRC2"]}
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interpro_conserved_site/basic/idx2term.json
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{"0": "WD40 repeat, conserved site [IPR019775]", "1": "Ubiquitin specific protease, conserved site [IPR018200]", "2": "Chaperonin TCP-1, conserved site [IPR002194]"}
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interpro_conserved_site/basic/plot_0.png
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interpro_conserved_site/basic/plot_1.png
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interpro_conserved_site/basic/plot_2.png
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interpro_conserved_site/consensus.joblib
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oid sha256:627e88b1672faea68647756f4a514a4d857bb0de8dd9dd3975081a0ce905a247
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size 98409
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interpro_conserved_site/df_merge.tsv
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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interpro_conserved_site/metrics.json
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{
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"type_of_task": "ranksum",
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"signature_size": 3210,
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"annotations_size": 277,
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"title": "Average number of proteins per term",
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| 6 |
+
"value": 2.7617328519855597
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| 7 |
+
}
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interpro_conserved_site/paths.json
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{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C409/C409_val_log2fc"}
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interpro_conserved_site/result.tsv
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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
|
| 2 |
+
Haem oxygenase conserved site [IPR018207] 0.9476309226932677 2.0870689794703785 0.0368818996555337 0.9999698537066032 0.1702714367430476 2 P30519 1
|
| 3 |
+
Ribosomal protein L24/L26, conserved site [IPR005825] 0.8759351620947651 1.7685272915479353 0.0769727938273399 0.9999999997685712 0.2698919479768754 2 P61254 1
|
| 4 |
+
Aldo/keto reductase, conserved site [IPR018170] 0.8569201995012481 1.68319333355966 0.0923376709326304 0.9999999999977868 0.3119211566870565 2 P15121 1
|
| 5 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752] 0.8541147132169591 1.6705812985453323 0.0948044089541086 0.9999999999989584 0.3163954371119049 2 O43175 1
|
| 6 |
+
Thioredoxin, conserved site [IPR017937] 0.5333782134812384 1.5564429151074997 0.1196028070297707 0.9999999999999996 0.3328206112390269 13 P07237,Q9H1E5,Q8NBS9,Q9H3N1 4
|
| 7 |
+
3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.8806610061250282 1.416469710654454 0.1566380263185869 1.0 0.416091924611906 3 Q08426 1
|
| 8 |
+
HMG box A DNA-binding domain, conserved site [IPR017967] 0.8346727940155451 1.2359260152091414 0.2164860658639307 1.0 0.4915737943654235 3 P09429 1
|
| 9 |
+
Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.7484413965087313 1.1949269688068846 0.2321155649742383 1.0 0.5087302823454506 2 P04439 1
|
| 10 |
+
Polyamine biosynthesis domain, conserved site [IPR030373] 0.7468827930174595 1.187961161792067 0.2348487114011876 1.0 0.5087302823454506 2 P19623 1
|
| 11 |
+
ABC transporter-like, conserved site [IPR017871] 0.4613196034011773 1.1689409409511995 0.2424274269660631 1.0 0.5087302823454506 14 P08183,P33527 2
|
| 12 |
+
Ribosomal S11, conserved site [IPR018102] 0.7369077306733198 1.143469485168548 0.2528437171905235 1.0 0.5226694750878733 2 P62263 1
|
| 13 |
+
Proteasome beta-type subunit, conserved site [IPR016050] 0.5301757133170903 1.0437484973769484 0.2966017655172486 1.0 0.5785823172413934 8 P28072,P49721 2
|
| 14 |
+
Mini-chromosome maintenance, conserved site [IPR018525] 0.5449798365475328 0.9261594574957492 0.3543631184450113 1.0 0.6023365743250315 6 P33992,P25205,P33991,Q14566 4
|
| 15 |
+
WD40 repeat, conserved site [IPR019775] 0.3151831973005214 0.8753492456592363 0.3813839066867435 1.0 0.6142054776292322 47 Q13347,O43172,Q9NV06,O60508,Q9GZL7,Q8TEQ6,P63244,P61962,Q04726,Q12788,Q8WWQ0,P78406,Q9UFC0,O43660,O43818,P43034,O75530,P62873 18
|
| 16 |
+
S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.6720698254364134 0.8602229659763488 0.389666147304482 1.0 0.6162144150614974 2 P23526 1
|
| 17 |
+
DNA ligase, ATP-dependent, conserved site [IPR016059] 0.6499376558603541 0.7672175117344046 0.4429522028235235 1.0 0.6415772130233436 2 P18858 1
|
| 18 |
+
Ubiquitin specific protease, conserved site [IPR018200] 0.3814587174506427 0.7284055222861622 0.4663653838173545 1.0 0.6590980169255469 16 P40818,O94966,O94782,Q9UPU5,Q86UV5,Q9P275,P51784,Q9Y4E8 8
|
| 19 |
+
Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.6327930174563643 0.6970582237361207 0.4857663570925581 1.0 0.6722484079438416 2 P24534 1
|
| 20 |
+
Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.4870294088537482 0.667754603358791 0.5042902488241938 1.0 0.6748231832091869 6 Q9UBF8,Q13535 2
|
| 21 |
+
DnaJ domain, conserved site [IPR018253] 0.3819982930210678 0.5915698464996586 0.5541386706549809 1.0 0.7008968574037886 12 O60884,Q96KC8,P31689,Q99543 4
|
| 22 |
+
Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.6493127478268368 0.5487383396153055 0.5831850310100095 1.0 0.7178894845687346 3 Q16539 1
|
| 23 |
+
ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.5826059850374127 0.5043483769865547 0.6140165876378934 1.0 0.7459762928758616 2 P53597 1
|
| 24 |
+
Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.6173994387277911 0.4469830195400947 0.654887320253013 1.0 0.771931011532275 3 Q9Y2T2,Q9BXS5 2
|
| 25 |
+
Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892] 0.362405862283508 0.4090933746422687 0.6824711381888344 1.0 0.7943046440265006 11 Q9UNP9,P30405,Q08752 3
|
| 26 |
+
Serpin, conserved site [IPR023795] 0.5252493765586105 0.3163260762867164 0.7517550205352441 1.0 0.8607632993140455 2 P35237 1
|
| 27 |
+
4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.5713751494420425 0.3159998873673115 0.7520025936245451 1.0 0.8607632993140455 3 O00217 1
|
| 28 |
+
D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.5497716579417455 0.2924165350702928 0.7699681672864391 1.0 0.8741032063046871 4 O43175 1
|
| 29 |
+
Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.3744787359189414 0.242599329572936 0.8083158006254321 1.0 0.9075371069934368 6 Q08426 1
|
| 30 |
+
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.2876656684499227 0.2183728989015931 0.8271385795434076 1.0 0.9164695461340956 17 Q9H2U1,Q7Z478 2
|
| 31 |
+
DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.4666458852867911 0.1722229762848876 0.8632622352930361 1.0 0.9387823245077062 2 P28340 1
|
| 32 |
+
AMP-binding, conserved site [IPR020845] 0.338001526731965 0.167138775581319 0.8672608566123303 1.0 0.9387823245077062 7 Q4G176,O60488,Q6P1M0,P33121 4
|
| 33 |
+
Polyprenyl synthetase, conserved site [IPR033749] 0.4638403990025018 0.1666936510749402 0.8676111013500822 1.0 0.9387823245077062 2 O95749 1
|
| 34 |
+
Aminotransferase, class IV, conserved site [IPR018300] 0.4507481296758188 0.1425753164160788 0.8866255929376585 1.0 0.9519197257508968 2 P54687 1
|
| 35 |
+
GTP1/OBG, conserved site [IPR006074] 0.4264339152119778 0.1050246714192862 0.9163562320161238 1.0 0.97534005240109 2 P55039 1
|
| 36 |
+
Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.4239401496259425 0.1016900239198238 0.9190027208544568 1.0 0.97534005240109 2 P06730 1
|
| 37 |
+
Chaperonin TCP-1, conserved site [IPR002194] 0.2945034353529006 0.0816708381205616 0.9349084686764556 1.0 0.9798346665457748 8 P50990,P50991,P78371,P48643,P49368,Q99832,P17987 7
|
| 38 |
+
Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.3879738060112828 0.0366377353699188 0.970773855242688 1.0 0.9992960683773926 4 P48735,O75874 2
|
| 39 |
+
IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.3291770573566164 0.032537891285393 0.9740430991404188 1.0 0.9992960683773926 2 P12268 1
|
| 40 |
+
Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842] 0.3042394014962676 0.0271695034227335 0.978324539465955 1.0 0.9999848613729504 2 P60891 1
|
| 41 |
+
Zinc finger, RING-type, conserved site [IPR017907] 0.2312578750030076 0.0207640334893948 0.9834338886669558 1.0 1.0 15 O60858,Q9H000,O95376,Q14527 4
|
| 42 |
+
Phosphofructokinase, conserved site [IPR015912] 0.319925163704401 0.0156943279483668 0.9874782520825802 1.0 1.0 3 P08237,P17858 2
|
interpro_conserved_site/selections.json
ADDED
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{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "Dihydroorotate dehydrogenase, conserved site [IPR001295]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase, RluC/RluD, conserved site [IPR006224]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPA, conserved site [IPR022658]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "Zinc finger, XPA-type, conserved site [IPR022652]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCC1", "ABCC4", "ABCD1", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATR", "BAG6", "BAX", "BAZ1A", "BAZ1B", "BCAT1", "BCAT2", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CHAF1B", "CHD1", "CHD1L", "CHD2", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COQ6", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHODH", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EHHADH", "EIF3I", "EIF4A1", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GRHPR", "GRWD1", "GSPT1", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "IVD", "KAT2A", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF13B", "KIF14", "KIF18A", "KIF1A", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MIF", "MKRN2", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MVK", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NF2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCGF6", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL3", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RECQL5", "RIDA", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RPUSD2", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE1", "SYNE2", "TAP1", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TTF2", "TUBB", "TUBB4B", "TUBB6", "TUFM", "TXN2", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "UIMC1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP33", "USP34", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR77", "XPA", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCC1", "ACSF3", "ACSL1", "ACSL4", "AHCY", "AKR1B1", "AP1M1", "AP3M1", "ARIH2", "ATR", "BCAT1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT7", "CCT8", "CDC40", "DCAF13", "DCAF7", "DHX29", "DHX36", "DNAJA1", "DNAJA2", "DNAJC1", "DNAJC2", "DRG2", "EED", "EEF1B2", "EHHADH", "EIF3I", "EIF4E", "GEMIN5", "GGPS1", "GNB1", "HLA-A", "HLTF", "HMGB1", "HMOX2", "IDH1", "IDH2", "IMPDH2", "LIG1", "LRWD1", "MAPK14", "MCM3", "MCM4", "MCM5", "MCM6", "MKRN2", "NDUFS8", "P4HB", "PAFAH1B1", "PFKL", "PFKM", "PHGDH", "PHIP", "PI4KB", "PLRG1", "POLD1", "PPID", "PPIE", "PPIF", "PRPF4", "PRPS1", "PSMB2", "PSMB6", "RACK1", "RAE1", "RPL26", "RPS14", "RRP9", "SERPINB6", "SLC27A4", "SRM", "SUCLG1", "TBL3", "TCP1", "TLE3", "TMX1", "TMX4", "TRIM13", "TXNDC5", "USP1", "USP11", "USP15", "USP19", "USP24", "USP36", "USP48", "USP8", "WDR12"]}
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{"0": "CS domain [IPR007052]", "1": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "2": "K Homology domain, type 1 [IPR004088]", "3": "Ubiquitin-associated domain [IPR015940]", "4": "Zinc finger C2H2-type [IPR013087]", "5": "RNA recognition motif domain [IPR000504]", "6": "Protein kinase domain [IPR000719]", "7": "K Homology domain [IPR004087]", "8": "Zinc finger, LIM-type [IPR001781]", "9": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "10": "Ubiquitin specific protease domain [IPR028889]", "11": "MPN domain [IPR037518]", "12": "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "13": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "14": "Glutathione S-transferase, C-terminal [IPR004046]", "15": "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "16": "Aminoacyl-tRNA synthetase, class Ia [IPR002300]"}
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interpro_domain/consensus.joblib
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version https://git-lfs.github.com/spec/v1
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oid sha256:2d79bd007e5ee50c8227f1d139fe141f3bdc48334a8a741e6081a9ce54fe70b0
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size 360067
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term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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Zinc finger, RanBP2-type [IPR001876] 2 9 2.086219990936934 0.0369587002072964 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 1.0 1.0 1.0 0.0130923880875091 0.0786846017539525
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LEM domain [IPR003887] 2 6 2.0089565720913667 0.0445417395249103 2.237864077669903 5.759708737864078 0.8787481060627674 0.3228260833428172 1.2758866328838632 0.4653299410110203 1.033781091163317 0.2887768895441466 0.0013376518177504 0.0273477531405618 0.0013106969968569 0.0080285789318432 0.0020257428393968
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