ligdis's picture
Upload folder using huggingface_hub
ff51dfa verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Antigen processing ubiquitination proteasome degradation 0.5198788870631648 3.5529785259524753 0.0003808955566952 0.3975120380954986 0.480007931067013 76 P60900,P49720,O94874,O00231,P55786,Q9H1A4,Q9UJX4,P19474,Q13867,P49427,Q92990,Q15386,A0AVT1,P28070,P28072,Q9UIQ6,P68036,P28074,P49721,Q9C0C9,Q13618,P52888,Q9Y4B6,Q99436,Q15008,Q9UJX3,P20618,O95376 28
Mitotic g2 g2 m phases 0.5075328225344499 3.3811556442626345 0.0007218164376947 0.6172458900557757 0.480007931067013 79 P60900,P49720,Q13885,P30153,O75935,O00231,P30154,Q13561,Q9H6D7,P28070,P14635,Q9BV73,O95684,P28074,P49721,P68371,P24941,Q9BVA1,Q99436,Q15691,P07437,P20618 22
G2 m checkpoints 0.4848172371518192 3.1765094363298374 0.0014905894014727 0.8624768357257042 0.6476326544465414 74 P60900,Q8N257,P49721,P49720,Q99436,P28070,P40938,P33991,Q9UQ84,Q14566,P24941,O60921,P14635,P20618,P28074 15
Deubiquitination 0.4607414744989921 2.801088698969859 0.0050930518189631 0.9988762312251795 0.6476326544465414 72 P60900,P49720,O00231,P45880,O15294,Q8N257,Q9Y4A5,P28070,Q8NB78,Q9Y3E5,Q93009,P28074,Q9UPU5,P49721,P21796,O14964,Q99436,Q86UV5,P20618 19
Organelle biogenesis and maintenance 0.4416204136627538 2.6409742398337026 0.0082668004681814 0.9999839618891802 0.6476326544465414 76 Q92973,A6NIH7,Q13885,P30153,O75935,Q13561,Q10713,P04350,Q9H6D7,Q13505,P78371,Q9BV73,Q9BZK7,P48643,O95684,O00411,P68371,Q9BVA1,Q15691,P07437,Q8IYI6,Q92538,O75964,P54646 24
Transferrin endocytosis and recycling 0.8127140156654341 2.558924086177576 0.0104996666887287 0.999999199785109 0.6476326544465414 9 Q9Y487,Q93050 2
Mapk family signaling cascades 0.4367354308623395 2.5349047548903205 0.0112477903277694 0.9999997073616728 0.6476326544465414 80 Q99436,P49721,P60900,P49720,P28070,Q9Y4G8,P30153,O15020,Q13618,O00231,P20618,P30154,P28074,O60725 14
Class i mhc mediated antigen processing presentation 0.4426719605339667 2.4508717963602455 0.0142510701204789 0.9999999948808485 0.6476326544465414 94 P60900,P49720,O94874,O00231,Q9NZ08,Q9H1A4,P55786,Q9UJX4,P19474,Q13867,P49427,Q92990,Q15386,A0AVT1,P28070,P28072,Q9UIQ6,Q15436,P68036,P28074,P49721,Q9C0C9,Q13618,P52888,Q9Y4B6,Q99436,P09429,Q15008,Q9UJX3,P20618,O95376,O94979 32
Iron uptake and transport 0.6666390912977853 2.4394792067134414 0.0147084491109437 0.9999999972386022 0.6476326544465414 16 Q9Y487,Q93050,P30519 3
Insulin receptor recycling 0.8238991821799604 2.4169651347174983 0.0156505161244646 0.999999999226264 0.6476326544465414 8 Q9Y487,Q93050 2
Sealing of the nuclear envelope ne by escrt iii 0.7430343775413519 2.353701256948608 0.0185875427803023 0.9999999999854594 0.6476326544465414 10 P68371,Q8NC56,Q13885,Q9UN37,Q9BVA1,O43633 6
Dna replication 0.4141956902592925 2.3147049289933657 0.0206290858437452 0.9999999999990884 0.6476326544465414 75 P60900,Q8N257,P49721,P49720,Q99436,P28070,P40938,P33991,Q14566,P24941,P20618,Q07864,Q9H1A4,P28074 14
Phase i functionalization of compounds 0.6781602837902909 2.2771312724833934 0.0227783877280827 0.9999999999999508 0.6476326544465414 13 O43169,Q16850,P07099 3
Ros and rns production in phagocytes 0.8281846527600136 2.2618954222983887 0.0237038652739822 0.999999999999986 0.6476326544465414 7 Q9Y487,Q93050 2
Cyclin a b1 b2 associated events during g2 m transition 0.8263351536952667 2.25389147419144 0.0242029961743723 0.999999999999993 0.6476326544465414 7 P30153,P14635,P24941 3
Ion channel transport 0.6072665699480575 2.2461525688721045 0.0246942371346634 0.9999999999999964 0.6476326544465414 23 Q9HD20,P23634,Q9Y487,Q93050 4
Signaling by insulin receptor 0.6719272791197112 2.2427181392840154 0.0249149961624077 0.9999999999999972 0.6476326544465414 13 Q9Y487,Q93050 2
Transport of inorganic cations anions and amino acids oligopeptides 0.7438569262312645 2.2311469205141714 0.0256713986049543 0.999999999999999 0.6476326544465414 9 Q70HW3 1
Cilium assembly 0.5521181865648218 2.222600994636478 0.0262427170926324 0.9999999999999996 0.6476326544465414 48 Q92973,A6NIH7,Q13885,P30153,O75935,Q13561,Q10713,P04350,Q9H6D7,P78371,Q9BV73,P48643,O95684,P68371,Q9BVA1,Q15691,P07437,Q8IYI6,Q92538 19
Signaling by the b cell receptor bcr 0.5713765935076374 2.184281323339566 0.0289415823024064 1.0 0.6476326544465414 41 P60900,P49721,Q99436,P49720,O43865,P28070,P28074,P20618,P62942 9
Purine salvage 0.859746651289211 2.182346121124702 0.0290839975307832 1.0 0.6476326544465414 5 P00813 1
Mitotic g1 phase and g1 s transition 0.4450931473349223 2.1815159054587117 0.0291452793239928 1.0 0.6476326544465414 67 P60900,P49721,Q99436,P49720,P28070,P33991,Q14566,P24941,P30153,P14635,O00231,P20618,Q07864,P28074 14
Cargo trafficking to the periciliary membrane 0.6360706519085857 2.1796796457102454 0.0292812163700382 1.0 0.6476326544465414 15 Q8IYI6,A6NIH7,P78371,Q92538,Q10713 5
S phase 0.4045448143096735 2.157548283712354 0.0309629692778101 1.0 0.6476326544465414 78 P60900,P49720,Q9Y2S7,P33991,Q14566,O00231,Q9H1A4,Q9UJX4,P28070,P28072,O43242,P28074,P49721,P24941,P11802,P49841,Q29RF7,Q99436,Q15008,P40938,Q9UJX3,Q9Y619,P20618,Q07864 24
Ub specific processing proteases 0.4801061616707676 2.1509017991361294 0.0314839515125324 1.0 0.6476326544465414 61 P60900,P49720,P45974,O00231,P45880,Q8N257,Q9Y4A5,P28070,P28072,O43242,Q9Y3E5,Q93009,P28074,Q9UPU5,P49721,Q8IXI2,P21796,O14964,Q99436,Q15008,Q92890,Q86UV5,P20618 23
The role of gtse1 in g2 m progression after g2 checkpoint 0.5467425071414477 2.1462637090494483 0.0318519452441874 1.0 0.6476326544465414 47 P60900,P49721,Q99436,P49720,Q15691,P68371,P28070,Q13885,Q9BVA1,P14635,O00231,P20618,P28074 13
Synthesis of dna 0.4267588972711237 2.1297472430586075 0.0331924863609096 1.0 0.6476326544465414 69 P60900,P49721,Q99436,P49720,P28070,P40938,P33991,Q14566,P24941,P20618,Q07864,Q9H1A4,P28074 13
Nucleotide salvage 0.8281756132172055 2.105521754238876 0.0352459157081004 1.0 0.6476326544465414 6 P00813 1
Degradation of dvl 0.5709855489106589 2.1053086563234187 0.0352644490952733 1.0 0.6476326544465414 37 P60900,P49721,Q99436,P49720,P28070,Q13618,P20618,P28074 8
Regulation of ras by gaps 0.567930152708888 2.099140360132534 0.0358045295189972 1.0 0.6476326544465414 38 P60900,P49721,Q99436,P49720,P28070,Q13618,O00231,P20618,P28074 9
G1 s dna damage checkpoints 0.5677308895580019 2.0976433862742083 0.0359366594362169 1.0 0.6476326544465414 38 P60900,P49721,Q99436,P49720,P28070,P24941,P20618,P28074 8
Apc c mediated degradation of cell cycle proteins 0.5331821622884756 2.0973942201701257 0.0359586923154866 1.0 0.6476326544465414 49 P60900,P49721,Q99436,P49720,P28070,P24941,P14635,P20618,Q9H1A4,P28074 10
Downstream signaling events of b cell receptor bcr 0.5622950859570005 2.0744196947478604 0.0380403497844732 1.0 0.6476326544465414 39 P60900,P49721,Q99436,P49720,P28070,P28074,P20618,P62942 8
Mastl facilitates mitotic progression 0.8327619415608136 2.071006053665959 0.0383582303349814 1.0 0.6476326544465414 5 P30153,P14635 2
Regulation of tp53 expression and degradation 0.7815317947076965 2.057835194189417 0.0396059563929576 1.0 0.6476326544465414 7 P30153,P24941,Q93009 3
Interleukin 1 family signaling 0.5484107502727069 2.050867884631894 0.0402798144313758 1.0 0.6476326544465414 43 P60900,P49721,Q99436,P49720,P09429,P28070,P40763,P20618,P28074 9
Regulation of runx3 expression and activity 0.5667661872095109 2.0450695649633053 0.0408480003094355 1.0 0.6476326544465414 35 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Tcf dependent signaling in response to wnt 0.5007208217352308 2.0427224352436646 0.0410799226117688 1.0 0.6476326544465414 55 P60900,Q8N257,Q9Y4A5,P49720,P49721,Q99436,P28070,P30153,Q13618,O00231,P30154,P49841,P20618,P28074 14
Carnitine metabolism 0.8251271873901225 2.039270786481922 0.0414230095687297 1.0 0.6476326544465414 5 O43772 1
Signaling by vegf 0.5735469796238057 2.03320860667684 0.0420314518977578 1.0 0.6476326544465414 19 Q14185,Q7L576,Q9UQB8,Q96F07 4
Hedgehog ligand biogenesis 0.5550589240595851 2.019282337280121 0.0434578826238358 1.0 0.6476326544465414 39 P60900,P49721,Q99436,P49720,P28070,P20618,Q9UBV2,P28074 8
Negative regulation of notch4 signaling 0.5535907721992286 2.0080636459696732 0.0446365287900667 1.0 0.6476326544465414 39 P60900,P49721,Q99436,P49720,P28070,O00231,P20618,P28074 8
Scf skp2 mediated degradation of p27 p21 0.5516723981368493 1.9933886161906704 0.0462189094528888 1.0 0.6476326544465414 39 P60900,P49721,Q99436,P49720,P28070,P24941,P20618,P28074 8
Cytoprotection by hmox1 0.4751582793390639 1.991271473890023 0.0464510498119492 1.0 0.6476326544465414 59 P60900,P49721,Q99436,P49720,P28070,P30519,P40763,Q13618,P20618,Q9BZK7,P28074 11
Class a 1 rhodopsin like receptors 0.8116866585681718 1.9831567270888928 0.0473499257959333 1.0 0.6476326544465414 5 P07602,P42892 2
Peptide ligand binding receptors 0.8116866585681718 1.9831567270888928 0.0473499257959333 1.0 0.6476326544465414 5 P07602,P42892 2
Interleukin 1 signaling 0.544770955623331 1.9780828861739792 0.047919356877595 1.0 0.6476326544465414 41 P60900,P49721,Q99436,P49720,P09429,P28070,P20618,P28074 8
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.6683180894604178 1.973635237145116 0.0484232340095782 1.0 0.6476326544465414 10 Q16763,A0AVT1,Q93009,Q96BN8,P68036,P49427 6
Degradation of axin 0.5542914946837657 1.966108609072215 0.049286066155042 1.0 0.6476326544465414 36 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Cross presentation of soluble exogenous antigens endosomes 0.5542914946837657 1.966108609072215 0.049286066155042 1.0 0.6476326544465414 36 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Transcriptional regulation by runx3 0.5480684215483754 1.965770440127684 0.0493251338207278 1.0 0.6476326544465414 39 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Uch proteinases 0.5366231758181377 1.9569571266463937 0.0503525092154439 1.0 0.6476326544465414 43 P60900,O15294,P49721,P49720,Q99436,P28070,O00231,P20618,P28074 9
Stabilization of p53 0.5509539737248946 1.9553485326685065 0.0505419464543155 1.0 0.6476326544465414 37 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Fcgamma receptor fcgr dependent phagocytosis 0.5635478093452954 1.954140595373884 0.0506845923253198 1.0 0.6476326544465414 24 Q9UQB8,O15143,Q7L576,Q14185,Q8IV08,Q96F07 6
Signaling by notch4 0.5413591507756502 1.9513781450250076 0.0510120793173611 1.0 0.6476326544465414 41 P60900,P49721,Q99436,P49720,P28070,O00231,P20618,P28074 8
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5432605600422679 1.946794412069365 0.051559387165615 1.0 0.6476326544465414 40 P60900,Q8N257,P49721,P49720,Q99436,Q03164,P28070,P20618,P28074 9
Cyclin a cdk2 associated events at s phase entry 0.5426457627669037 1.9420226941598495 0.0521343530126416 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P24941,P20618,P28074 8
Degradation of beta catenin by the destruction complex 0.5243048497858087 1.931908935771895 0.0533707466744373 1.0 0.6476326544465414 46 P60900,P49721,Q99436,P49720,P28070,P30153,O00231,P30154,P20618,P28074 10
Switching of origins to a post replicative state 0.4921390380713868 1.921351128925548 0.054687455321424 1.0 0.6476326544465414 54 P60900,P49721,Q99436,P49720,P28070,P33991,Q14566,P24941,P20618,Q9H1A4,P28074 11
Orc1 removal from chromatin 0.5152602687360448 1.9134348132921923 0.0556924111941299 1.0 0.6476326544465414 48 P60900,P49721,Q99436,P49720,P28070,P33991,Q14566,P24941,P20618,P28074 10
Regulation of pten stability and activity 0.5438740114742581 1.9018896487978212 0.0571855827242731 1.0 0.6476326544465414 37 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Regulation of plk1 activity at g2 m transition 0.5532067130366941 1.8996046057480225 0.0574850273580271 1.0 0.6476326544465414 30 Q15691,Q9H6D7,P68371,P30153,P14635,O75935,Q9BV73,O95684 8
Intracellular signaling by second messengers 0.3998830553639565 1.89220084908566 0.0584642252946463 1.0 0.6476326544465414 70 P60900,P49721,Q99436,P49720,O43865,P28070,Q93009,P30153,O00231,P20618,P28074 11
Cellular response to chemical stress 0.4188081234767891 1.885393001844075 0.0593767981508501 1.0 0.6476326544465414 67 P60900,P49721,Q99436,P49720,P28070,P30519,P40763,Q13618,P20618,Q9BZK7,P28074 11
Formation of tubulin folding intermediates by cct tric 0.606756792684361 1.8753061250983256 0.060750621204477 1.0 0.6476326544465414 13 P68371,Q9BUF5,Q13885,Q9BVA1,P78371,P48643,P04350 7
Rho gtpases activate wasps and waves 0.5830494210327091 1.8632460584662371 0.0624276554866753 1.0 0.6476326544465414 15 O15143,Q9UQB8,Q7L576 3
Aurka activation by tpx2 0.5497005192563171 1.8601925505127512 0.0628582886413409 1.0 0.6476326544465414 26 Q15691,Q9H6D7,P68371,P30153,O75935,Q9BV73,O95684 7
Abc family proteins mediated transport 0.5074949406743717 1.8473133863780065 0.0647017339556259 1.0 0.6476326544465414 48 P60900,P49721,Q99436,P49720,P28070,P08183,P20618,Q9UBV2,P28074 9
Metabolism of polyamines 0.5312510768764571 1.8360750846968663 0.0663465526182849 1.0 0.6476326544465414 39 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.5240917160255641 1.835059420536066 0.0664968856738057 1.0 0.6476326544465414 42 P60900,P49721,Q99436,P49720,Q15008,P28070,P28072,O43242,P28074,Q9UJX3,O00231,P20618,Q9H1A4,Q9UJX4 14
Assembly and cell surface presentation of nmda receptors 0.7310036570499837 1.8318940035623408 0.0669672141225081 1.0 0.6476326544465414 7 Q9BUF5,P68371,Q13885,Q9BVA1,Q15334,P04350 6
Anchoring of the basal body to the plasma membrane 0.5452664512951622 1.831046866689978 0.0670935481004229 1.0 0.6476326544465414 27 Q15691,Q9H6D7,P68371,P30153,O75935,Q9BV73,O95684 7
Parasite infection 0.5429582395275426 1.8309597747387227 0.0671065472838132 1.0 0.6476326544465414 19 Q14185,Q7L576,Q9UQB8,O15143 4
Transcriptional regulation by ventx 0.6169278394875192 1.823169922299348 0.0682776590161173 1.0 0.6476326544465414 11 Q16763,Q9H9B1,Q96KQ7,Q9UJX3,Q9UJX2,Q9H1A4,Q9UJX4 7
Regulation of hmox1 expression and activity 0.5206638273246593 1.8076480371530812 0.0706612967586404 1.0 0.6476326544465414 42 P60900,P49721,Q99436,P49720,P28070,Q13618,P20618,P28074 8
Hedgehog on state 0.5243656412135269 1.7993214500182677 0.0719678469330646 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,Q13618,P20618,P28074 8
Phosphorylation of the apc c 0.6882709711628036 1.7876542084677047 0.0738318138543112 1.0 0.6476326544465414 8 Q16763,Q9UJX3,P14635,Q9H1A4,Q9UJX4 5
Apc c cdc20 mediated degradation of cyclin b 0.6882709711628036 1.7876542084677047 0.0738318138543112 1.0 0.6476326544465414 8 Q16763,Q9UJX3,P14635,Q9H1A4,Q9UJX4 5
Carboxyterminal post translational modifications of tubulin 0.7530463038180248 1.786232200749298 0.0740616693569493 1.0 0.6476326544465414 6 Q14166,P68371,Q13885,Q9BVA1,P04350 5
Asymmetric localization of pcp proteins 0.5285651733978971 1.7855210935804746 0.0741768330048671 1.0 0.6476326544465414 37 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Degradation of gli1 by the proteasome 0.5224255212918696 1.7840859318604527 0.0744097028898727 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Transcriptional regulation by runx2 0.5058867990962669 1.7784417310688834 0.0753313339588865 1.0 0.6476326544465414 46 P60900,P49721,Q99436,P49720,Q15008,P28070,P28072,O43242,P14635,O00231,P11802,P49841,P20618,P42224,P28074 15
Recruitment of mitotic centrosome proteins and complexes 0.5373191508331548 1.7751628924137677 0.0758709948464004 1.0 0.6476326544465414 27 Q15691,Q9H6D7,P68371,P30153,O75935,Q9BV73,O95684 7
Signaling by interleukins 0.3881669527757 1.7741197545537672 0.0760433438400542 1.0 0.6476326544465414 93 Q99436,P49721,P60900,P09429,P49720,P28070,O14979,P14174,Q13126,P78417,P30153,P40763,O00231,P20618,P30154,P28074,P52597 17
Abc transporter disorders 0.5200898878397909 1.7657224632241757 0.0774424222488401 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P20618,Q9UBV2,P28074 8
Defective cftr causes cystic fibrosis 0.5200898878397909 1.7657224632241757 0.0774424222488401 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P20618,Q9UBV2,P28074 8
Metabolism of folate and pterines 0.7482515679013315 1.7655297571354236 0.0774747736406054 1.0 0.6476326544465414 6 Q9H2D1 1
Dna replication pre initiation 0.4615980921201121 1.762059545673564 0.0780592373738529 1.0 0.6476326544465414 57 P60900,Q8N257,P49721,P49720,Q99436,P28070,P33991,Q14566,P24941,P20618,Q07864,P28074 12
Regulation of mrna stability by proteins that bind au rich elements 0.4499926214084939 1.7417163489455734 0.0815580902949797 1.0 0.6476326544465414 59 P60900,P49721,Q99436,P49720,Q15008,Q92973,P28070,P28072,O43242,Q01105,Q92945,O00231,Q9NPI6,P20618,P39687,Q14103,P28074,Q9NQT5 18
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.7963090530091466 1.7356384241734115 0.0826277874238314 1.0 0.6476326544465414 4 P30153 1
Transport of connexons to the plasma membrane 0.7527405602923178 1.733535641748398 0.0830005082339377 1.0 0.6476326544465414 5 Q9BVA1,P04350,Q13885,P68371 4
Gap junction assembly 0.7527405602923178 1.733535641748398 0.0830005082339377 1.0 0.6476326544465414 5 Q9BVA1,P04350,Q13885,P68371 4
Recruitment of numa to mitotic centrosomes 0.5292997530974667 1.733278602640183 0.0830461620306033 1.0 0.6476326544465414 31 Q15691,P07437,Q9H6D7,P68371,Q13885,P30153,Q9BVA1,O75935,Q13561,Q9BV73,O95684 11
Activation of ampk downstream of nmdars 0.7086963593536544 1.7306254123432043 0.0835185962109084 1.0 0.6476326544465414 7 P68371,Q13885,Q9BVA1,P54646,P04350 5
Regulation of runx2 expression and activity 0.5134208547036206 1.7131591763124605 0.0866832597215736 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,O00231,P20618,P28074 8
Dectin 1 mediated noncanonical nf kb signaling 0.5133483139294036 1.7125864018990282 0.0867886567058293 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Tnfr2 non canonical nf kb pathway 0.5133483139294036 1.7125864018990282 0.0867886567058293 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Homologous dna pairing and strand exchange 0.5872027612889164 1.7080545084614822 0.0876262288260365 1.0 0.6476326544465414 12 Q9UQ84,O60921 2
Hdr through single strand annealing ssa 0.5872027612889164 1.7080545084614822 0.0876262288260365 1.0 0.6476326544465414 12 Q9UQ84,O60921 2
Separation of sister chromatids 0.3792372990859371 1.7040273497241274 0.0883759778313189 1.0 0.6476326544465414 89 P60900,P49720,Q13885,P49792,P30153,O75122,Q8WUM0,O43264,Q9UJX2,O00231,P30154,Q9H1A4,P04350,Q9UJX4,P28070,P28072,O43242,Q8NFH4,P28074,P49721,Q16763,Q96FJ2,P68371,Q9BVA1,Q29RF7,Q99436,Q15691,Q15008,Q9BUF5,Q9UJX3,P20618 31
Clec7a dectin 1 signaling 0.5049661111196511 1.7013219896874134 0.088882540980739 1.0 0.6476326544465414 43 P60900,P49721,Q99436,P49720,O43865,P28070,P20618,P28074 8
Fceri mediated nf kb activation 0.5115727983295121 1.6985603550701425 0.0894020516194846 1.0 0.6476326544465414 40 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Pregnenolone biosynthesis 0.7848147784691422 1.688084497467404 0.0913950098843767 1.0 0.6476326544465414 4 P30536 1
Signaling by hedgehog 0.4627022140207199 1.6876333314887304 0.0914816367592565 1.0 0.6476326544465414 55 P60900,P49721,Q99436,P49720,Q15008,P68371,P28070,P28072,P13861,Q13885,Q9BVA1,Q13618,O00231,P20618,P49841,Q9UBV2,P04350,P28074 18
Diseases of dna repair 0.6669899100376415 1.6853279960553682 0.0919253071884331 1.0 0.6476326544465414 8 P43246,Q9UQ84,P52701,P20585,O60934 5
Rhobtb1 gtpase cycle 0.5201685270919071 1.685305007723459 0.0919297400688092 1.0 0.6476326544465414 18 P61201,Q8N684,Q9BT78,Q13618,Q5VTR2,P08670 6
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.7839025953716297 1.6843038698706336 0.0921229578998295 1.0 0.6476326544465414 4 P30153 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.5427489263142152 1.6827399071540003 0.0924254526559238 1.0 0.6476326544465414 16 P68371,Q9BUF5,O15212,Q13885,P78371,Q9BVA1,P48643,P04350 8
Neddylation 0.4182667140072506 1.6822573342703897 0.0925189506352202 1.0 0.6476326544465414 64 P60900,P49721,Q99436,P49720,P61201,P28070,Q9BT78,Q8N668,Q13618,O00231,P20618,P28074 12
Gpcr ligand binding 0.6640336566563769 1.6710468758406558 0.0947124192243791 1.0 0.6543231170056483 8 Q9BYT8,P07602,P42892,Q9UBI6 4
C type lectin receptors clrs 0.4938955415648247 1.6537140072307044 0.0981856352544503 1.0 0.6595297721637321 45 P60900,P49721,Q99436,P49720,O43865,P28070,P20618,P28074 8
Signaling by notch 0.4536275053108752 1.6419116763082515 0.1006083096926837 1.0 0.6624210489666801 56 P60900,Q8N257,P49721,P49720,Q99436,P28070,O00231,P20618,Q9BZK7,Q9UBV2,P28074 11
Pp2a mediated dephosphorylation of key metabolic factors 0.8750581149566913 1.6274165731027332 0.1036486539996452 1.0 0.6733111325741684 3 P30153 1
Apc cdc20 mediated degradation of nek2a 0.6532418637144333 1.6187842728933746 0.105493687134341 1.0 0.6733111325741684 8 Q16763,Q9UJX3,Q9UJX2,Q9H1A4,Q9UJX4 5
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.6532418637144333 1.6187842728933746 0.105493687134341 1.0 0.6733111325741684 8 Q16763,Q9UJX3,Q9UJX2,Q9H1A4,Q9UJX4 5
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.7115025217279479 1.6057116518151549 0.1083372799780992 1.0 0.6733111325741684 6 Q9UJX3,Q16763,Q9UJX4,Q9H1A4 4
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.7115025217279479 1.6057116518151549 0.1083372799780992 1.0 0.6733111325741684 6 Q9UJX3,Q16763,Q9UJX4,Q9H1A4 4
Signaling by wnt 0.3599499988583184 1.5941095827026883 0.110911492981206 1.0 0.6771940101354866 77 Q99436,P49721,P60900,Q8N257,Q9Y4A5,P49720,P28070,Q9UBI6,P30153,Q13618,O00231,P20618,P30154,P49841,P28074 15
Cellular response to hypoxia 0.4983159705850282 1.593442989557069 0.1110608481472095 1.0 0.6771940101354866 40 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Cdt1 association with the cdc6 orc origin complex 0.4997146733552468 1.5895306342192588 0.1119406435191496 1.0 0.6771940101354866 39 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Fc epsilon receptor fceri signaling 0.4831712833787264 1.5869400514106096 0.1125262227367989 1.0 0.6771940101354866 46 P60900,P49721,Q99436,P49720,O43865,P28070,P20618,P28074 8
Initiation of nuclear envelope ne reformation 0.5049780305272357 1.5828975964625092 0.1134448066729605 1.0 0.6796468147524212 18 P30153,Q86XL3,Q8IXJ6 3
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5071415362322328 1.5617778798974251 0.1183403245391105 1.0 0.6981269044368446 28 Q96FJ2,P68371,Q02790,Q15185,Q13885,Q9BVA1,Q13451,O75935,Q13561,Q14203,P04350 11
Hedgehog off state 0.4670894280123911 1.5541723099734006 0.1201433205879154 1.0 0.6988018827664999 50 P60900,P49721,Q99436,P49720,Q15008,P68371,P28070,P28072,P13861,O43242,Q9BUF5,Q13885,Q9BVA1,O00231,P20618,P49841,P04350,P28074 18
Regulation of tp53 activity through phosphorylation 0.505203191788147 1.5539303189034992 0.1202010387407428 1.0 0.6988018827664999 23 Q9UQ84,P24941,O60921,Q92804 4
Cell cycle checkpoints 0.3902401887298635 1.5534317466682848 0.1203200234237056 1.0 0.6988018827664999 116 P60900,P49720,P33991,Q14566,P30153,O75122,O43264,O00231,P30154,Q9H1A4,Q8N257,P28070,Q9UQ84,P14635,P28074,P49721,P24941,Q99436,Q15691,P40938,O60921,P20618 22
Striated muscle contraction 0.7505872850601354 1.5456094409712289 0.1221989197447608 1.0 0.7035695379243805 4 P08670,P67936 2
Nuclear signaling by erbb4 0.8534302062361498 1.542504024730833 0.1229511606660109 1.0 0.7048493262318732 3 P61201 1
Post chaperonin tubulin folding pathway 0.5835562835838006 1.5250271366864163 0.1272523292764207 1.0 0.7232717860582887 10 P68371,Q99426,Q13885,Q15813,Q9BTW9,Q9BVA1,P04350 7
Biological oxidations 0.4967325668340612 1.5119381528806275 0.1305495969334471 1.0 0.7346159012430754 34 Q9NUJ1,O43169,Q16850,P07099 4
Processing of dna double strand break ends 0.4952450081121874 1.5011172535147213 0.1333252369910442 1.0 0.7411153289968935 20 Q8N257,P24941,O60921,Q9UQ84 4
Transport of small molecules 0.4017100465868422 1.497161211779455 0.1343513154401352 1.0 0.7411153289968935 137 P60900,P49720,Q70HW3,Q93050,Q9UBI6,P04920,Q9HD20,Q8WTV0,P28070,P30519,P11166,P28074,P49721,Q99808,Q9Y487,P38606,Q8N4V1,Q99436,P08183,P23634,P20618,Q9UBV2 22
Metabolism of steroid hormones 0.6976281069140187 1.4956615620279092 0.1347418717291548 1.0 0.7411153289968935 5 P30536 1
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7375406778153605 1.4910102115789774 0.1359588139270986 1.0 0.7439723728781754 4 Q9BZK7 1
Auf1 hnrnp d0 binds and destabilizes mrna 0.4818850908807042 1.4774732740776635 0.1395488172104939 1.0 0.7544712475201502 41 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Ion transport by p type atpases 0.57290511908069 1.4675964355468665 0.1422138768089806 1.0 0.7626792586933238 10 Q9HD20 1
Mrna decay by 3 to 5 exoribonuclease 0.5427027669952144 1.452997417345427 0.1462244710788192 1.0 0.7810383394973074 12 Q969T7,Q6PGP7,Q9NQT5 3
Negative regulation of mapk pathway 0.56783071259881 1.4401738880596604 0.1498182088300024 1.0 0.7934907308719078 10 P30153,P30154,P28482 3
Signaling by receptor tyrosine kinases 0.3618723173225183 1.4313226873171585 0.1523377546777473 1.0 0.7984582813785064 93 Q9UQB8,P61201,Q9Y487,O43865,P38606,Q93050,P30153,Q96F07,P40763,P30154,Q14185,Q7L576,P52597,P16949,P46109 15
Mismatch repair 0.6117300368970996 1.4161035328567315 0.1567451938963944 1.0 0.8049077524409443 8 P20585,Q9UQ84,P52701,P43246 4
Signaling by erbb4 0.6673436230706519 1.4114165570674102 0.1581218237573556 1.0 0.8057548873459117 6 P62993,P61201,Q96J02,P16949,Q15334 5
Interferon gamma signaling 0.5807020663455522 1.4082849407121163 0.1590467130452233 1.0 0.8071618422266655 9 P19474 1
Senescence associated secretory phenotype sasp 0.4876672527334249 1.394329212779824 0.1632182132573998 1.0 0.822273574364931 17 Q8N257,Q16763,Q9H9B1,Q96KQ7,P24941,Q9UJX3,P40763,P11802,Q9H1A4,Q9UJX4,P28482 11
Transcriptional regulation of granulopoiesis 0.635281012344747 1.3919907620101255 0.163925195402665 1.0 0.8227189052284698 7 Q8N257,P40763,Q03164 3
Cholesterol biosynthesis 0.4956736635684691 1.3819359200766104 0.1669913775469615 1.0 0.8278253448143813 16 Q15392,P14324,Q9BWD1,Q16850,P37268 5
Tcr signaling 0.4647243254073749 1.370459786337736 0.1705434202204978 1.0 0.8278253448143813 43 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Signaling by ctnnb1 phospho site mutants 0.6565341965923582 1.363582038482784 0.172699148303064 1.0 0.8278253448143813 6 P30153,P30154 2
Beta catenin phosphorylation cascade 0.6565341965923582 1.363582038482784 0.172699148303064 1.0 0.8278253448143813 6 P30153,P30154 2
Disassembly of the destruction complex and recruitment of axin to the membrane 0.6565341965923582 1.363582038482784 0.172699148303064 1.0 0.8278253448143813 6 P30153,P30154 2
Antigen processing cross presentation 0.4485989795636367 1.361937618337263 0.1732175729431291 1.0 0.8278253448143813 49 P60900,P49721,Q99436,P49720,P09429,P28070,Q9UIQ6,P20618,P28074 9
Regulation of tp53 activity through methylation 0.7067880922066777 1.3618630062345825 0.1732411229272366 1.0 0.8278253448143813 4 Q9H9B1,O14744 2
Regulation of tp53 activity 0.4736192820294327 1.3605479343736584 0.1736565948896333 1.0 0.8278253448143813 37 P40938,Q9H9B1,Q9UQ84,Q92804,P30153,Q93009,P24941,O60921,P30154 9
Pten regulation 0.4278273423973602 1.3551976640188108 0.1753545887594498 1.0 0.8299701176159014 55 P60900,P49721,Q99436,P49720,P28070,Q93009,P20618,P28074 8
Hur elavl1 binds and stabilizes mrna 0.6634532562296952 1.3466253072367331 0.178100939290815 1.0 0.8339972947583455 5 Q01105 1
Role of phospholipids in phagocytosis 0.9209245742092445 1.3446912206970645 0.1787249709565901 1.0 0.8339972947583455 2 Q8IV08 1
Growth hormone receptor signaling 0.6614416988205486 1.3378304544187505 0.1809517118530266 1.0 0.8364579883164719 5 P42224,P40763 2
Mitotic prometaphase 0.3382839742202868 1.332290933582288 0.182764605239087 1.0 0.8401567316472458 75 Q13885,P30153,O75122,O43264,O75935,Q13561,P30154,P04350,Q9H6D7,P14635,Q8NFH4,Q9BV73,O95684,Q96FJ2,P68371,Q9BVA1,Q29RF7,Q15691,P07437 19
Diseases of mitotic cell cycle 0.5648917371619802 1.3259396256459968 0.1848596962374902 1.0 0.8448913951747834 9 Q16763,P24941,Q9UJX3,P11802,Q9H1A4,Q9UJX4 6
Diseases of mismatch repair mmr 0.7963488843813353 1.3174759109938785 0.1876791504532398 1.0 0.8519224235590749 3 P52701,P43246 2
Interaction between l1 and ankyrins 0.6950252875039603 1.31235916207889 0.1893989790597712 1.0 0.8539004818626974 4 O15020,Q13813 2
Copi independent golgi to er retrograde traffic 0.4695048610618717 1.289003167198972 0.1973969854964266 1.0 0.872608096988447 28 Q96FJ2,P68371,Q15042,Q13885,Q9BVA1,O75935,Q13561,P04350,Q8TD16 9
Uptake and actions of bacterial toxins 0.5851579494923826 1.2853759748421958 0.1986609325478321 1.0 0.872608096988447 8 Q16881,Q7L0J3,Q8WUM4 3
Miscellaneous transport and binding events 0.6491766910239083 1.2841751362987717 0.1990806828224833 1.0 0.872608096988447 5 P35611,Q8N4V1 2
Circadian clock 0.5548329450788643 1.273448499930997 0.2028589364083384 1.0 0.8778505895513139 9 Q9BZK7 1
Heme signaling 0.6458303902372762 1.2695298952802307 0.2042521350521848 1.0 0.8791434939139349 5 Q9BZK7 1
Slc mediated transmembrane transport 0.4611393397786612 1.2655131742199888 0.2056874288246799 1.0 0.8798069784536615 20 P04920,Q99808,P11166,Q70HW3 4
Mitotic metaphase and anaphase 0.3717256433376372 1.261146897653051 0.207255926603721 1.0 0.8809736435386257 121 P60900,P49720,Q92973,Q8N1F7,Q13885,P30153,O75122,O43264,O00231,P30154,Q9H1A4,P28070,Q9UN37,P14635,Q8NFH4,P28074,P49721,P68371,Q9BVA1,Q86XL3,Q29RF7,Q99436,Q15691,Q8IXJ6,Q8NC56,O43633,P20618 27
Protein ubiquitination 0.4646203281664863 1.2599842634217957 0.2076750391487134 1.0 0.8809736435386257 25 Q16763,Q92541,A0AVT1,P45974,Q6PD62,Q93009,O75150,Q14527,Q5VTR2,Q96BN8,P04439,P68036,P49427 13
Intraflagellar transport 0.5315128972144352 1.243079390300113 0.2138385796218687 1.0 0.8970000925963533 10 P68371,Q92973,Q13885,Q9BVA1,P04350 5
Signaling by pdgfr in disease 0.6744916892107294 1.2259150742611025 0.2202306355041705 1.0 0.9030108078271648 4 P42224,P40763 2
Rhobtb3 atpase cycle 0.772192858353058 1.2222413935078371 0.2216163546666743 1.0 0.9030108078271648 3 Q13618 1
Ctla4 inhibitory signaling 0.6725970732708739 1.2179416374805718 0.2232461519709963 1.0 0.9030108078271648 4 P30153 1
Platelet sensitization by ldl 0.6725970732708739 1.2179416374805718 0.2232461519709963 1.0 0.9030108078271648 4 P30153 1
Darpp 32 events 0.5704720794190952 1.212971595000715 0.2251406807325779 1.0 0.9030108078271648 8 P30153,P30154 2
Metabolism of steroids 0.4531536452325147 1.2004165546960903 0.2299776026488078 1.0 0.9030108078271648 37 P30536,Q15392,Q9BWD1,Q16850,Q15436,Q9BZK7 6
Sphingolipid de novo biosynthesis 0.5384093409706172 1.187665039121734 0.2349654027568419 1.0 0.9030108078271648 9 O15121,Q96G23,Q06136 3
Condensation of prophase chromosomes 0.5635578949292095 1.1788780480532934 0.2384467400574403 1.0 0.9030108078271648 8 Q8N257,Q01105 2
Diseases of signal transduction by growth factor receptors and second messengers 0.3683889542133458 1.177711225439564 0.2389117501745994 1.0 0.9030108078271648 125 P60900,P49720,Q9UBW7,P12270,P30153,P40763,O00231,P30154,Q7Z2W4,P62942,Q86WB0,P28070,P28072,O43242,P06753,P42224,Q9BZK7,P67936,O95684,P28074,P30876,P33176,P21359,Q00610,P49721,Q9NRY5,P49841,P35579,Q9NR09,Q99436,P51114,Q15008,P20618,Q14203,Q9UBV2,O94979 36
Ncam signaling for neurite out growth 0.6135839304641342 1.1730512344304236 0.2407752605236637 1.0 0.9030108078271648 6 O15020,Q13813,P28482 3
Activation of atr in response to replication stress 0.4539545826137621 1.170089617698117 0.2419649061436937 1.0 0.9030108078271648 17 P33991,P24941,P40938,O60921 4
Mapk6 mapk4 signaling 0.4317816385308578 1.1676671147324773 0.2429410666122327 1.0 0.9030108078271648 47 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Disorders of transmembrane transporters 0.3355124921110786 1.1669800284274072 0.2432184349617465 1.0 0.9030108078271648 71 P60900,P49721,Q99436,P49720,Q15008,P28070,P28072,Q8N1F7,O43242,P12270,Q99567,P11166,O00231,Q8NFH4,P20618,Q9UBV2,P28074 17
Unwinding of dna 0.5870442433729752 1.1668745076673157 0.2432610521109079 1.0 0.9030108078271648 7 P33991 1
Platelet homeostasis 0.5147295875762453 1.1517785563503762 0.2494120817775029 1.0 0.9065541048408896 10 P30153,P23634,Q9UBI6 3
Synthesis of substrates in n glycan biosythesis 0.5146060699561166 1.1511068109955314 0.2496882963109989 1.0 0.9065541048408896 10 Q16222,P34949,Q8NFW8 3
Bmal1 clock npas2 activates circadian gene expression 0.7529411764705805 1.1465523987816182 0.2515666593500993 1.0 0.9065541048408896 3 Q9BZK7,Q86X55 2
Tp53 regulates transcription of cell cycle genes 0.5122872428199123 1.138497285036057 0.2549128919078427 1.0 0.9097705199011724 10 Q9NZN8,P14635,Q86X55,P24941 4
Cyclin d associated events in g1 0.5524220636062128 1.1239959856595738 0.2610147289528837 1.0 0.9232701848599344 8 P30153,P30154,P24941 3
G2 m dna damage checkpoint 0.4451300226616839 1.11357452436089 0.2654617606050045 1.0 0.9294618787970887 27 Q8N257,P14635,O60921,Q9UQ84 4
Signaling by wnt in cancer 0.5733789819661419 1.103110081618279 0.2699793632465956 1.0 0.9350847737447192 7 P30153,P30154 2
Irf3 mediated induction of type i ifn 0.6069574728240392 1.0995253066829431 0.2715390018378736 1.0 0.9356136591823104 5 P78527,P49959,P13010 3
Selective autophagy 0.4414975546672791 1.0873038760934866 0.276902536161038 1.0 0.9362005550773038 27 P68371,Q9NS69,P21796,Q13885,Q9BVA1,P08670,P54646,P04350 8
Prolonged erk activation events 0.5940140747158488 1.086312823385492 0.2773406155642539 1.0 0.9362005550773038 6 P28482,P46109 2
Signaling by ptk6 0.4833545138169707 1.0724488498652511 0.2835184766965024 1.0 0.9511539530485492 11 Q14185,P40763,P11802,P24941 4
Vxpx cargo targeting to cilium 0.5896654754823951 1.0670752659748364 0.285937849822691 1.0 0.9511539530485492 6 Q8IYI6 1
Signaling by braf and raf1 fusions 0.4319375128675533 1.0629364891031683 0.2878107540449122 1.0 0.9539369086053898 20 P51114,Q6WCQ1,P41240,Q7Z2W4,Q9NRY5,P36507,P28482 7
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5871846197151567 1.0561085524575726 0.2909186234906085 1.0 0.9539369086053898 6 P14635,Q86X55 2
Condensation of prometaphase chromosomes 0.538380836307359 1.0549135333706376 0.2914648721596429 1.0 0.9539369086053898 8 Q9BPX3,Q15021,Q9NTJ3,Q15003,P19784,P14635 6
Pink1 prkn mediated mitophagy 0.5601920124240112 1.0417125308405848 0.2975449775829719 1.0 0.9644612553267512 7 Q9NS69 1
Sema4d induced cell migration and growth cone collapse 0.5785887726109801 1.018164628083689 0.3085997261915034 1.0 0.9731574061495224 6 P35579,P35580 2
Epha mediated growth cone collapse 0.5785887726109801 1.018164628083689 0.3085997261915034 1.0 0.9731574061495224 6 P35579,P35580 2
E2f mediated regulation of dna replication 0.5053560254158038 1.015338495454439 0.3099445002388097 1.0 0.9731574061495224 9 P30153,P14635,P30154 3
Cytochrome c mediated apoptotic response 0.6239588369356234 1.014057963261287 0.3105550949676141 1.0 0.9731574061495224 4 P42574,P28482 2
Signaling by alk in cancer 0.4314492261041449 1.0089790698857228 0.3129846720838696 1.0 0.9731574061495224 30 Q00610,Q86WB0,O94979,P12270,P40763,P06753,Q14203,P35579,P67936,Q9NR09,P33176,P28482 12
Transcriptional regulation of white adipocyte differentiation 0.5520675183616335 1.0039881201493928 0.3153843397778177 1.0 0.9731574061495224 7 Q9BZK7,P11802 2
Gap junction trafficking and regulation 0.4693568105870411 0.9933039203083672 0.3205618676488786 1.0 0.9731574061495224 11 Q00610,P68371,Q9BUF5,Q13885,Q9BVA1,Q07157,P04350 7
Kinesins 0.4252731575774106 0.979380200932161 0.3273921561548198 1.0 0.9731574061495224 17 P68371,Q9NSK0,Q13885,Q9BVA1,Q12756,P52732,P04350,P33176 8
Regulation of lipid metabolism by pparalpha 0.4506243811079521 0.9545511719824236 0.3398047197070228 1.0 0.983708984883 13 Q9BZK7,Q16881,P23786,P37268 4
Hdr through homologous recombination hrr 0.4108239304485228 0.9388882293799692 0.3477881331503412 1.0 0.9919248094134157 18 Q9UQ84,Q07864,O60921 3
Beta catenin independent wnt signaling 0.3953799349741089 0.9337636319945782 0.3504258332186145 1.0 0.9919248094134157 51 P60900,P49721,Q99436,P49720,P28070,Q9UBI6,P20618,P28074 8
Transcriptional regulation by runx1 0.3626180413315095 0.9317915155370596 0.3514442802361246 1.0 0.9919248094134157 61 P60900,Q8N257,P49721,P49720,Q99436,Q03164,P28070,P20618,P28074 9
Regulation of cholesterol biosynthesis by srebp srebf 0.4131379786566051 0.9234927501635858 0.3557504767595483 1.0 0.9919248094134157 21 P14324,Q16850,Q15436,Q9BZK7,P37268 5
Aggrephagy 0.4312052144299638 0.9186252736327624 0.3582916078232765 1.0 0.9962728969766828 15 P68371,Q13885,Q9BVA1,P08670,P04350 5
Ptk6 regulates cell cycle 0.8106244931062401 0.915310222841576 0.3600287938775852 1.0 0.9962728969766828 2 P24941 1
Activation of nmda receptors and postsynaptic events 0.4095266115312184 0.9082614882904712 0.363740084450443 1.0 0.9962728969766828 20 P52292,P13861,P68371,Q9BUF5,P10644,Q13885,P54646,Q9BVA1,P49593,Q15334,P04350,Q14168,P28482 13
Fcgr3a mediated il10 synthesis 0.5980970191009184 0.9069662905520054 0.3644246235778867 1.0 0.9962728969766828 4 O43865 1
Pcp ce pathway 0.4012130408808685 0.9033785471140872 0.3663250217578073 1.0 0.9963441287073288 47 P60900,P49721,Q99436,P49720,P28070,P20618,P28074 7
Intra golgi and retrograde golgi to er traffic 0.3069712224861574 0.8927411010303485 0.3719958344343104 1.0 1.0 77 Q8TBA6,P24390,Q13885,O43264,O75935,Q13561,P04350,O43493,O00461,P53621,O14653,P52732,Q96FJ2,Q99747,P68371,Q9BVA1,P11717,Q12756,Q9Y3Q3,P35606,Q15042,Q9NSK0,Q92538,Q14203,Q8TD16,Q9Y678 26
Rora activates gene expression 0.8033252230332444 0.8877712829453234 0.3746637930778473 1.0 1.0 2 Q9BZK7 1
Interferon alpha beta signaling 0.4800176278912333 0.8844068464267517 0.3764766284548222 1.0 1.0 9 P42224,Q9Y3Z3,Q13325 3
Small interfering rna sirna biogenesis 0.6836932970024452 0.8782919127699261 0.3797853234651078 1.0 1.0 3 Q9UPY3 1
Mitophagy 0.5019996012537271 0.8773592335206208 0.3802915484112565 1.0 1.0 8 Q9NS69 1
Transcriptional activation of mitochondrial biogenesis 0.4624255464024283 0.8692033789389434 0.384735899593092 1.0 1.0 10 Q9BZK7 1
Glycerophospholipid biosynthesis 0.4031600544811416 0.8547507359409224 0.3926891562814645 1.0 1.0 21 Q8IV08,Q9NPH0,P35790 3
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6762677484786929 0.8501387239888011 0.3952479644481839 1.0 1.0 3 P42224,P40763 2
Signaling by kit in disease 0.6762677484786929 0.8501387239888011 0.3952479644481839 1.0 1.0 3 P42224,P40763 2
Interleukin 2 family signaling 0.6762677484786929 0.8501387239888011 0.3952479644481839 1.0 1.0 3 P42224,P40763 2
Late endosomal microautophagy 0.5184692504234814 0.8493623611678854 0.3956796902253929 1.0 1.0 7 Q99816,P08670 2
Protein folding 0.4096331166759952 0.8477272270631548 0.3965898995349504 1.0 1.0 32 P04062,Q9Y2T2,O15212,P50990,Q99426,P68371,Q9BUF5,Q13885,Q15813,Q9UBI6,Q9BTW9,P78371,Q9BVA1,P40763,P48643,P04350 16
Autophagy 0.4067806095997547 0.8286800771830661 0.4072854621654467 1.0 1.0 34 Q99816,P68371,Q9NS69,P21796,Q13885,Q9BVA1,O43633,P08670,P54646,P04350 10
Uptake and function of diphtheria toxin 0.5771103896103903 0.8212682596061306 0.4114934829858034 1.0 1.0 4 Q16881,P07900,P08238 3
Notch3 activation and transmission of signal to the nucleus 0.6672125778251403 0.8160355051556198 0.4144798291510796 1.0 1.0 3 Q9Y6A5 1
Metabolism of water soluble vitamins and cofactors 0.4040812948009642 0.8146301295137997 0.4152840586903321 1.0 1.0 28 P78417,P11166,P34896,Q9H2D1 4
Phase ii conjugation of compounds 0.3966491605543397 0.8101745665052084 0.4178398528685427 1.0 1.0 21 Q9NUJ1,P78417 2
Rac2 gtpase cycle 0.4041924062037172 0.8097445594760532 0.4180870022540146 1.0 1.0 30 Q14185,P49257,Q86XL3,Q13505 4
Recognition and association of dna glycosylase with site containing an affected purine 0.5396804224580407 0.8096455218010006 0.4181439370083613 1.0 1.0 5 Q8N257 1
Base excision repair ap site formation 0.5396804224580407 0.8096455218010006 0.4181439370083613 1.0 1.0 5 Q8N257 1
G alpha i signalling events 0.3942473746422268 0.8039382008280288 0.4214326666129171 1.0 1.0 20 O43865,P07602,Q9UBI6,P30153,P63096 5
Nr1h2 and nr1h3 mediated signaling 0.5286853896009631 0.8006919043432493 0.4233100304387862 1.0 1.0 6 Q9BZK7 1
Downstream signal transduction 0.5358235631441429 0.7933835382951514 0.427554398733097 1.0 1.0 5 P40763,P46109 2
Signaling by pdgf 0.5358235631441429 0.7933835382951514 0.427554398733097 1.0 1.0 5 P40763,P46109 2
Bbsome mediated cargo targeting to cilium 0.5268394252157307 0.7927820252877668 0.4279048307237665 1.0 1.0 6 P78371,P48643 2
Leishmania infection 0.4019818424153146 0.7914348565983331 0.42869027626881 1.0 1.0 32 Q9UQB8,P35579,O43865,Q9Y2Z0,Q9UBI6,O15143,Q7L576,P63096,Q14185,Q96F07 10
Protein localization 0.3502025775458965 0.7656030646791259 0.443912520395604 1.0 1.0 60 Q8NBU5,Q9NS69,Q13505,Q3ZCQ8,P46379,Q99595 6
Interleukin 21 signaling 0.7700729927007224 0.7646659896978625 0.444470463230979 1.0 1.0 2 P40763 1
Interleukin 9 signaling 0.7700729927007224 0.7646659896978625 0.444470463230979 1.0 1.0 2 P40763 1
Adaptive immune system 0.3601261198766158 0.7620555415238527 0.4460268556953488 1.0 1.0 159 P60900,P49720,Q13885,P30153,O94874,O75935,O00231,P30154,Q13561,Q9NZ08,P55786,Q9H1A4,Q9UJX4,P19474,P62942,Q13867,P04350,P49427,Q92990,Q15386,A0AVT1,P28070,P28072,O43242,Q9UIQ6,Q15436,P52732,P68036,P28074,P33176,Q00610,P49721,Q96FJ2,O43865,P68371,Q9C0C9,Q9BVA1,Q13618,P52888,P78310,Q9Y4B6,Q99436,P09429,Q15008,Q9NSK0,O15020,Q9UJX3,P20618,Q14203,O95376,O94979 51
Metabolism of porphyrins 0.4971372682315714 0.7529733990106523 0.4514658992089297 1.0 1.0 7 P30519 1
Vitamin c ascorbate metabolism 0.6482823705556222 0.745670030366782 0.4558667674830925 1.0 1.0 3 P11166 1
M phase 0.3662519362032838 0.7437877366287765 0.4570049004064189 1.0 1.0 171 P60900,P49720,Q92973,Q8N1F7,Q13885,P12270,P30153,O75122,O43264,O75935,O00231,P30154,Q13561,Q9H1A4,P04350,Q9UJX4,Q8N257,Q9H6D7,P28070,P28072,Q9UN37,P14635,Q8NFH4,Q9BV73,O95684,P28074,P49721,Q96FJ2,P68371,Q01105,Q08379,Q15003,Q9BVA1,Q86XL3,P42695,Q29RF7,Q99436,Q15691,Q15008,P07437,Q8IXJ6,Q8NC56,Q99567,Q9UJX3,O43633,P20618,Q14203,Q9Y6X3 48
Signaling by notch3 0.5143067979619409 0.7394337051046898 0.4596436819241063 1.0 1.0 6 P67809,Q9Y6A5 2
Apoptotic cleavage of cell adhesion proteins 0.5224138305802303 0.7373014898492425 0.4609390264099333 1.0 1.0 5 Q07157,P42574,P15924 3
Response of eif2ak1 hri to heme deficiency 0.6434077079107426 0.7277792123509086 0.4667487515802162 1.0 1.0 3 P05198,P08243 2
Mitochondrial protein import 0.3926981088408948 0.724968354867899 0.4684714443767765 1.0 1.0 31 Q13505,Q3ZCQ8,Q99595,Q9NS69 4
Pyroptosis 0.510137577390032 0.7218356020987823 0.4703955578690606 1.0 1.0 6 P09429,O43633 2
Erks are inactivated 0.5061307789880439 0.7050002261181924 0.4808100954456895 1.0 1.0 6 P30153 1
Rhobtb gtpase cycle 0.386619449186183 0.701827213388092 0.4827869254018688 1.0 1.0 26 P61201,Q8N684,Q9BT78,Q13618,Q5VTR2,P08670 6
Sialic acid metabolism 0.5436120659053486 0.6877860784132857 0.4915875042255071 1.0 1.0 4 Q8NFW8 1
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3789340128310262 0.6806457779117185 0.4960956532881511 1.0 1.0 22 O14979,P14174,P52597,Q13126 4
Toll like receptor tlr1 tlr2 cascade 0.4020714685996049 0.6728159757917248 0.5010643727859074 1.0 1.0 13 P30153,P09429 2
Nuclear envelope ne reassembly 0.3727560118311033 0.6623882794079065 0.5077224132439297 1.0 1.0 47 P68371,Q92973,Q8N1F7,Q13885,Q8NC56,Q9UN37,Q8IXJ6,P30153,Q9BVA1,P14635,Q8NFH4,Q86XL3,O43633 13
Uptake and function of anthrax toxins 0.624158821799139 0.6581912162594666 0.5104152682953114 1.0 1.0 3 Q8WUM4 1
Interleukin 12 family signaling 0.3810814082742935 0.6577988793392582 0.5106673746052084 1.0 1.0 27 O14979,P14174,Q13126,P40763,P52597 5
Arachidonic acid metabolism 0.4906064819556508 0.6405641723990765 0.5218058832995578 1.0 1.0 6 Q8N8N7 1
Homology directed repair 0.3799514065156924 0.6404467528545831 0.5218821959249129 1.0 1.0 29 Q8N257,Q9UQ84,P24941,O60921,Q07864 5
Endosomal sorting complex required for transport escrt 0.4495181762048738 0.6295792780623701 0.5289698847463926 1.0 1.0 8 Q99816,O43633,Q9UN37 3
Negative feedback regulation of mapk pathway 0.5274797804473553 0.6254409193509664 0.5316817129341647 1.0 1.0 4 P28482 1
Ras activation upon ca2 influx through nmda receptor 0.7295214922952167 0.6212634914437594 0.5344262706563079 1.0 1.0 2 Q15334 1
Unblocking of nmda receptors glutamate binding and activation 0.7295214922952167 0.6212634914437594 0.5344262706563079 1.0 1.0 2 Q15334 1
Long term potentiation 0.7295214922952167 0.6212634914437594 0.5344262706563079 1.0 1.0 2 Q15334 1
Rho gtpase effectors 0.2998355605802162 0.6204966448903984 0.5349308622230557 1.0 1.0 93 Q9UQB8,P35080,Q13885,P30153,O75122,O43264,P30154,P04350,Q8N257,Q8NFH4,P35580,Q96F07,P68371,Q9BVA1,P35579,Q15691,Q9NSK0,O15143,Q16513,Q7L576 20
Translation of replicase and assembly of the replication transcription complex 0.6099377355417429 0.6080052099930846 0.5431840184422019 1.0 1.0 3 O43633 1
Golgi to er retrograde transport 0.3165608615050727 0.6075163231569557 0.5435083132848357 1.0 1.0 65 Q13885,P24390,O43264,O75935,Q13561,P04350,P52732,Q96FJ2,Q99747,P68371,Q9BVA1,Q12756,Q9Y3Q3,P35606,Q15042,Q9NSK0,Q92538,Q8TD16,Q9Y678 19
Aryl hydrocarbon receptor signalling 0.6095287436834356 0.6065789239958725 0.5441303906125758 1.0 1.0 3 Q15185 1
Cohesin loading onto chromatin 0.4431947081860402 0.6008324684326847 0.5479515761708622 1.0 1.0 8 Q9Y6X3 1
Sensory processing of sound by outer hair cells of the cochlea 0.3973830446965349 0.5984935305238352 0.5495106743848099 1.0 1.0 11 P23634,Q00013 2
Apoptosis 0.2875865561571527 0.5956617002474814 0.5514012490458398 1.0 1.0 81 Q99436,P49721,P60900,P09429,P49720,P28070,O00429,P40763,P20618,P26583,P28074 11
Signaling by cytosolic fgfr1 fusion mutants 0.4585529208018785 0.5844511226628207 0.5589168403963578 1.0 1.0 7 O95684 1
Signaling by fgfr1 in disease 0.4585529208018785 0.5844511226628207 0.5589168403963578 1.0 1.0 7 O95684 1
Fgfr1 mutant receptor activation 0.4585529208018785 0.5844511226628207 0.5589168403963578 1.0 1.0 7 O95684 1
Myd88 independent tlr4 cascade 0.3858819395470646 0.582602581940345 0.5601608668871525 1.0 1.0 13 P30153,P09429 2
Intrinsic pathway for apoptosis 0.3636308056410877 0.5815067033087803 0.5608990017393927 1.0 1.0 17 Q96FJ2,P27348,P42574,P40763,P28482 5
Complex i biogenesis 0.3585605164720378 0.567444167135387 0.5704124496421121 1.0 1.0 20 Q9Y6M9,O96000,O75306 3
Downregulation of erbb2 signaling 0.5117963773167744 0.5663589085642595 0.5711498223613456 1.0 1.0 4 Q96RT1,Q93034 2
Toll like receptor 9 tlr9 cascade 0.372115006312725 0.5618012394994473 0.5742514475084088 1.0 1.0 15 P30153,P09429 2
Interleukin 12 signaling 0.3616948780746103 0.5485751415024044 0.5832970492165472 1.0 1.0 24 O14979,P14174,P52597,Q13126 4
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4660583171738491 0.5417562493696111 0.5879864343995413 1.0 1.0 6 Q9Y2Z0,P42575 2
Smac xiap regulated apoptotic response 0.7051905920519065 0.5398530981450284 0.589298345257478 1.0 1.0 2 P42574 1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3778994813798041 0.5391513002158523 0.589782460427867 1.0 1.0 13 Q16222,P34949,Q8NFW8 3
Cardiac conduction 0.3979361500982001 0.5371465575051574 0.5911663832928635 1.0 1.0 10 P23634 1
Ion homeostasis 0.3979361500982001 0.5371465575051574 0.5911663832928635 1.0 1.0 10 P23634 1
Ire1alpha activates chaperones 0.3555151390553719 0.5370486957437557 0.5912339778593032 1.0 1.0 21 Q9HCU5,P51858,O14653,Q14203,O94979 5
Sensing of dna double strand breaks 0.503492724870012 0.5357744274276524 0.5921144579713853 1.0 1.0 4 O60934,P49959 2
Budding and maturation of hiv virion 0.4462071759198426 0.5327035805066861 0.5942387872171018 1.0 1.0 7 Q99816,O43633,Q9UN37 3
Sirt1 negatively regulates rrna expression 0.5004459873434256 0.5246841292767257 0.5998027918958644 1.0 1.0 4 Q8N257 1
Dna damage recognition in gg ner 0.3703033631794969 0.5228511369029292 0.6010778504308827 1.0 1.0 14 P61201 1
Formation of apoptosome 0.5847260577593962 0.5220755586430734 0.601617723225955 1.0 1.0 3 P28482 1
Constitutive signaling by overexpressed erbb2 0.4985747665993764 0.5179092292861861 0.6045216023518529 1.0 1.0 4 P62993,Q96RT1 2
Signaling by erbb2 ecd mutants 0.4985747665993764 0.5179092292861861 0.6045216023518529 1.0 1.0 4 P62993,Q96RT1 2
Signaling by erbb2 in cancer 0.4985747665993764 0.5179092292861861 0.6045216023518529 1.0 1.0 4 P62993,Q96RT1 2
Activation of gene expression by srebf srebp 0.3528953336834679 0.5159361933097574 0.6058989745023335 1.0 1.0 17 Q9BZK7,P14324,Q16850,P37268 4
Cargo concentration in the er 0.3755218365100079 0.5047863619298435 0.6137088957064074 1.0 1.0 12 Q15436 1
Cell surface interactions at the vascular wall 0.3748165673123833 0.5011472519132953 0.6162674940372326 1.0 1.0 12 P14174,P78310 2
Folding of actin by cct tric 0.4205263612449501 0.5005817606333848 0.6166655015517679 1.0 1.0 8 P78371,P48643 2
Nucleotide biosynthesis 0.3724947257316636 0.4892143980658376 0.6246899171541362 1.0 1.0 12 P30520,P49915,P22102,P27708,Q06203 5
Erk mapk targets 0.4342197879801596 0.4837399021520386 0.6285704709962732 1.0 1.0 7 P30153 1
Mapk targets nuclear events mediated by map kinases 0.4342197879801596 0.4837399021520386 0.6285704709962732 1.0 1.0 7 P30153 1
Interleukin 27 signaling 0.5717801844263235 0.4796914311404283 0.6314468218124187 1.0 1.0 3 P40763 1
Interleukin 35 signalling 0.5717801844263235 0.4796914311404283 0.6314468218124187 1.0 1.0 3 P40763 1
Integration of energy metabolism 0.3489767005385977 0.4756810963565678 0.6343015903636242 1.0 1.0 23 O43865,Q9UBI6,P30153,P63096,P11166,P30154 6
Mitotic telophase cytokinesis 0.3850193389053585 0.4750703261874758 0.63473684809213 1.0 1.0 10 Q9Y6X3 1
Inactivation of csf3 g csf signaling 0.4559990424624914 0.4747417822517276 0.6349710330776026 1.0 1.0 5 P42224,P40763,Q93034 3
Transport to the golgi and subsequent modification 0.3071540578237639 0.4699232899820342 0.6384098240752727 1.0 1.0 64 Q9HCU5,Q13885,P24390,O75935,Q13561,P04350,P53621,Q15436,P49257,Q96FJ2,Q99747,P68371,Q08379,Q9BVA1,Q9Y3Q3,P35606,O15020,Q92538,Q14203,O94979,Q9Y678 21
Linoleic acid la metabolism 0.6828872668288642 0.4689781252322973 0.6390852718801505 1.0 1.0 2 O95864 1
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.3718949877954187 0.4687301652744793 0.6392625223494917 1.0 1.0 11 P78371,P48643,Q9UBI6,P50990 4
Sensory perception 0.3445929341592938 0.4682069266644596 0.639636619244903 1.0 1.0 21 P50579,P23634 2
Nuclear events kinase and transcription factor activation 0.3825370510047256 0.4633794967199282 0.6430923725005626 1.0 1.0 10 P30153 1
Suppression of apoptosis 0.4821428571428533 0.4596845388653412 0.6457426688035941 1.0 1.0 4 P23246,P49840,P28482 3
Purine ribonucleoside monophosphate biosynthesis 0.3918762314422712 0.4550861177864193 0.6490472848142723 1.0 1.0 9 Q06203,P49915,P22102,P30520 4
Er to golgi anterograde transport 0.3088538014463554 0.4524126795450875 0.6509717142510096 1.0 1.0 63 Q9HCU5,Q13885,P24390,O75935,Q13561,P04350,P53621,Q15436,P49257,Q96FJ2,Q99747,P68371,Q08379,Q9BVA1,Q9Y3Q3,P35606,O15020,Q92538,Q14203,O94979,Q9Y678 21
Beta oxidation of lauroyl coa to decanoyl coa coa 0.4780844155844121 0.4456772880479603 0.6558303727775305 1.0 1.0 4 Q16836,P40939,P30084 3
Beta oxidation of hexanoyl coa to butanoyl coa 0.4780844155844121 0.4456772880479603 0.6558303727775305 1.0 1.0 4 Q16836,P40939,P30084 3
Deadenylation dependent mrna decay 0.3496295305807674 0.4362149640870471 0.6626807718802645 1.0 1.0 29 Q9Y450,Q6PGP7,Q969T7,P23588,Q96F86,Q9NQT5 6
Cdc42 gtpase cycle 0.3452266218959068 0.427073882360191 0.669325515371693 1.0 1.0 26 Q9UQB8 1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3848249896371505 0.4239012122909164 0.6716378600081594 1.0 1.0 9 Q03164 1
Activated notch1 transmits signal to the nucleus 0.6662611516626102 0.418809129021899 0.6753556325219741 1.0 1.0 2 Q96J02 1
Noncanonical activation of notch3 0.6662611516626074 0.4188091290218905 0.6753556325219803 1.0 1.0 2 P67809 1
Thrombin signalling through proteinase activated receptors pars 0.439766289179104 0.4159942008443229 0.6774142467402517 1.0 1.0 5 Q14344,Q9UBI6 2
Rac3 gtpase cycle 0.3462630715329112 0.41456398087982 0.6784611206231443 1.0 1.0 29 P49257,Q9UQB8 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4159962152447364 0.4121098808844482 0.6802588866958903 1.0 1.0 7 O60725 1
Opioid signalling 0.3350563323235909 0.411063203727151 0.6810261903961521 1.0 1.0 17 P30153,P63096,O43865,Q9UBI6 4
Muscle contraction 0.3352745753583991 0.4008213117971292 0.6885516869820418 1.0 1.0 22 P08670,P67936,O43865,P23634 4
Signal attenuation 0.5453339097248284 0.3973986849587747 0.6910734850830935 1.0 1.0 3 P28482 1
Meiotic recombination 0.376639369032939 0.3885651331862368 0.6975978634596662 1.0 1.0 9 Q8N257,P49959,P24941,P11802,O60934 5
Regulated necrosis 0.348844261119462 0.3884654034960441 0.6976716517475379 1.0 1.0 13 O15294,P09429,O43633,Q8WUM4 4
Dna repair 0.2713207674222703 0.3844014505618197 0.7006809255688147 1.0 1.0 82 Q8N257,P61201,P43246,P40938,Q9UQ84,P52701,O60921,Q93009,P24941,P29372,Q9NVI1,Q07864 12
Transcriptional regulation by tp53 0.2778778844688254 0.3812201374471605 0.7030399078191152 1.0 1.0 90 P43246,P30153,P00390,P30154,Q9NQ88,Q16881,Q9UQ84,Q93009,Q9NVI1,P14635,P30876,P42575,Q9NZN8,Q92804,P24941,P30044,P40938,Q86X55,Q9H9B1,O14744,O60921,P54646 22
Activation of ppargc1a pgc 1alpha by phosphorylation 0.652879156528783 0.3802522657476015 0.7037581653070775 1.0 1.0 2 P54646 1
Translocation of slc2a4 glut4 to the plasma membrane 0.3412829349155528 0.3778342073238795 0.705553760346072 1.0 1.0 30 P68371,Q8IYI6,Q13885,Q9UIQ6,Q9BVA1,P35579,P54646 7
Regulation of insulin secretion 0.3492627454179137 0.37432114320894 0.7081654035957983 1.0 1.0 12 P63096,P11166,O43865 3
Signaling by fgfr in disease 0.3410555170372863 0.3682809618701816 0.71266374672486 1.0 1.0 14 P30876,O95684,P40763 3
Association of tric cct with target proteins during biosynthesis 0.3321745808615836 0.366958459702757 0.713650004012194 1.0 1.0 16 P78371,P40763,Q9Y2T2 3
Hiv transcription initiation 0.3714732193473187 0.3667767818743048 0.7137855278657328 1.0 1.0 9 Q92804 1
Mtor signalling 0.3583215202781589 0.3540423618474308 0.7233071364564725 1.0 1.0 10 P23588,P62942 2
Golgi cisternae pericentriolar stack reorganization 0.3663770146260365 0.3456963073463635 0.7295709596781634 1.0 1.0 9 P14635 1
Map2k and mapk activation 0.3555736371033453 0.3422346113152816 0.7321743400403489 1.0 1.0 10 P18206,P27361,P41240,Q02750,P31946,P30086,P46940,P36507,P28482 9
Cytokine signaling in immune system 0.3208280998548099 0.3421290660435053 0.7322537643444829 1.0 1.0 151 P60900,P49720,P30153,P40763,O00231,P30154,Q9Y4X5,P52597,P19474,P46109,P28070,O00629,P28074,P49721,P14174,Q13126,P29372,Q99436,P09429,O14979,P78417,P20618,Q13325 23
Signaling by hippo 0.4178711475235592 0.3413375806411965 0.7328494596048771 1.0 1.0 5 Q07157,P42574 2
Hdacs deacetylate histones 0.3377596394487819 0.3347802232569293 0.7377908800725228 1.0 1.0 13 Q9BZK7 1
Interleukin 20 family signaling 0.5227835442884502 0.3324230564567406 0.7395698309644827 1.0 1.0 3 P40763 1
Interleukin 17 signaling 0.3422630350018348 0.3296984385439075 0.7416278336976581 1.0 1.0 11 P30153 1
Dag and ip3 signaling 0.407372482024931 0.32738499602593 0.7433767132046292 1.0 1.0 6 P52292,O43865,P13861 3
Antigen presentation folding assembly and peptide loading of class i mhc 0.3388141391682688 0.3145447856323336 0.7531073071672023 1.0 1.0 11 Q15436 1
Programmed cell death 0.2712255055399926 0.3131266956191355 0.7541844080250848 1.0 1.0 89 Q99436,P49721,P60900,P09429,P49720,P28070,O00429,P40763,O00231,P20618,P26583,P28074 12
Rho gtpases activate iqgaps 0.3468656132630814 0.305721650173688 0.7598165876207084 1.0 1.0 10 Q9BVA1,Q13885,P68371 3
Anti inflammatory response favouring leishmania parasite infection 0.3351965439927022 0.2989097456613632 0.7650089109146554 1.0 1.0 11 O43865,Q9Y3E5,Q9UBI6,P63096,P35579 5
Mitochondrial biogenesis 0.3223889429930159 0.2752130329047929 0.783152574644592 1.0 1.0 28 Q9BZK7,Q13505 2
Nectin necl trans heterodimerization 0.6123276561232744 0.2745156997286706 0.7836883402326826 1.0 1.0 2 Q9BY67 1
Class b 2 secretin family receptors 0.5006533906627388 0.2739456864295277 0.7841263613361762 1.0 1.0 3 Q9UBI6 1
Activation of the pre replicative complex 0.3138089166471146 0.2723990648835579 0.7853151916402781 1.0 1.0 16 P33991,Q07864,P24941 3
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.39548887394495 0.2713315096193308 0.78613607395036 1.0 1.0 5 Q15334,P28482 2
Beta oxidation of butanoyl coa to acetyl coa 0.4993914807302109 0.2707804637925064 0.7865598863644103 1.0 1.0 3 Q16836,P30084 2
Negative regulation of the pi3k akt network 0.3471444525224728 0.270176187978372 0.7870247109552819 1.0 1.0 9 P30153 1
Rho gtpases activate cit 0.3462852868395699 0.2669620432582842 0.7894983858519398 1.0 1.0 9 P35579,Q7Z406,Q15334,P35580 4
Activation of bh3 only proteins 0.3420089467263164 0.2511799802058504 0.8016749619791645 1.0 1.0 9 Q96FJ2,Q04917,P27348,P61981,P63167,P63104,P04637,P31946 8
Formation of the beta catenin tcf transactivating complex 0.3419222192132908 0.2508636710877798 0.8019195126725065 1.0 1.0 9 Q8N257 1
Asparagine n linked glycosylation 0.2714517336447374 0.2494346015480237 0.8030246226237201 1.0 1.0 96 Q9HCU5,Q8NFW8,P24390,Q13885,O75935,Q13561,P04350,Q16222,Q15436,P49257,Q96FJ2,Q99747,P34949,P68371,Q08379,Q9BVA1,Q9Y3Q3,P35606,O15020,Q92538,Q9UBV2,Q9Y678 22
Inositol phosphate metabolism 0.488642156624931 0.2445920266228814 0.8067723384064669 1.0 1.0 3 Q9NPH2 1
Cargo recognition for clathrin mediated endocytosis 0.3124357771879977 0.2420666961325064 0.8087284835042912 1.0 1.0 25 P61201,Q9BT78,O14964,Q14108,O43493 5
Tp53 regulates transcription of death receptors and ligands 0.5952960259529562 0.2355484713163189 0.8137830622681159 1.0 1.0 2 P04637 1
Caspase activation via extrinsic apoptotic signalling pathway 0.5952960259529559 0.2355484713163186 0.8137830622681161 1.0 1.0 2 P42574 1
Interconversion of nucleotide di and triphosphates 0.3148799189247883 0.2323367082756569 0.8162765032916144 1.0 1.0 13 Q16881,P22392,P17812,P31350 4
Signaling by erbb2 0.3640796424217913 0.2318406236827495 0.81666180339718 1.0 1.0 7 P62993,P07900,O60610,Q93034,Q96RT1,Q16543 6
E3 ubiquitin ligases ubiquitinate target proteins 0.3053179641744041 0.2315871365600655 0.8168586994634932 1.0 1.0 16 Q92541,Q6PD62,Q14527,Q5VTR2,P04439,P68036,O75150 7
Estrogen dependent nuclear events downstream of esr membrane signaling 0.4819472616632725 0.2289961298924259 0.818871924111942 1.0 1.0 3 O14980,P28482 2
Phospholipid metabolism 0.3163375485240305 0.228729273558519 0.8190793408537296 1.0 1.0 30 Q8IV08,Q9NPH0,P35790 3
Mtorc1 mediated signalling 0.3628545459798519 0.2280931552275867 0.8195738211927217 1.0 1.0 7 P62942 1
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3076835112914661 0.2262079960167572 0.8210396518659615 1.0 1.0 15 O43852,O43493,Q02818 3
Copi dependent golgi to er retrograde traffic 0.3185497378879328 0.2199511229816844 0.8259092206975214 1.0 1.0 42 P68371,P35606,Q9NSK0,Q13885,P24390,Q9BVA1,Q92538,O43264,Q12756,P52732,P04350,Q9Y3Q3,Q9Y678 13
Toll like receptor cascades 0.2968464161652571 0.2198173404319154 0.8260134142059152 1.0 1.0 19 P30153,P09429 2
Dna strand elongation 0.2967144370497442 0.2191534055861236 0.826530550123296 1.0 1.0 19 P33991,P40938 2
Synthesis of very long chain fatty acyl coas 0.3713144737246147 0.2170109763832241 0.8281997908543477 1.0 1.0 6 O60488,Q9NZ01,P33121 3
Oas antiviral response 0.4734279918864001 0.2099642126578824 0.8336956045792292 1.0 1.0 3 P61221,P21333 2
Hcmv infection 0.3113718885690021 0.2088362604715426 0.8345760636213984 1.0 1.0 49 Q8N1F7,Q13885,P49792,P12270,Q8WUM0,P61978,P04350,Q8N257,Q9UN37,Q8NFH4,Q9BZK7,Q99816,Q96FJ2,P68371,Q9BVA1,P37198,Q9BUF5,Q99567,O43633 19
Hdr through mmej alt nhej 0.3647441104792889 0.1990608442695272 0.8422151499729238 1.0 1.0 6 P49959,Q92878,P09874,P39748,O60934 5
Signalling to erks 0.3264992217154232 0.1970983878476694 0.8437505449945935 1.0 1.0 9 P36507,P28482,P46109 3
Rho gtpases activate rocks 0.3385105227769042 0.1929565149128731 0.846993024094761 1.0 1.0 8 P35579,P35580 2
Dna double strand break repair 0.3146790222907799 0.1928155429530483 0.8471034303884852 1.0 1.0 39 Q8N257,Q9UQ84,P24941,O60921,Q07864 5
Nuclear events stimulated by alk signaling in cancer 0.3070720276551566 0.1927324969174682 0.8471684717133661 1.0 1.0 12 Q00610,Q86WB0,P40763,P33176 4
Metabolism of vitamins and cofactors 0.31370671087279 0.1906242947577698 0.8488199547470536 1.0 1.0 36 P78417,Q9H2D1,P11166,Q8N0U8,P34896 5
Sensory processing of sound 0.2947934994220886 0.1838797163365069 0.8541078174955434 1.0 1.0 16 P23634,Q00013 2
Regulation of localization of foxo transcription factors 0.3855519480519453 0.1787890858139072 0.8581033154594966 1.0 1.0 4 P27348,P61981,P31946 3
Signaling by csf3 g csf 0.3456314729557562 0.1782352468122996 0.8585382299211677 1.0 1.0 7 P62993,P42224,P40763,Q93034 4
Smooth muscle contraction 0.3124579717182358 0.176757638823375 0.8596987643600831 1.0 1.0 10 P67936 1
Vasopressin regulates renal water homeostasis via aquaporins 0.3604122489283894 0.176604168862684 0.8598193192813888 1.0 1.0 5 Q9UBI6 1
Aquaporin mediated transport 0.3604122489283894 0.176604168862684 0.8598193192813888 1.0 1.0 5 Q9UBI6 1
Glucagon signaling in metabolic regulation 0.3604122489283894 0.176604168862684 0.8598193192813888 1.0 1.0 5 Q9UBI6 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.4569189584934778 0.1757430378544721 0.8604958221576025 1.0 1.0 3 P24941 1
Miro gtpase cycle 0.448275862068951 0.1592535718866474 0.8734690981113087 1.0 1.0 3 O95140,Q8IXI2 2
Deadenylation of mrna 0.3069902645545213 0.1587790712709094 0.8738429383207564 1.0 1.0 10 Q9NZN8,P23588 2
Ngf stimulated transcription 0.4450304259634765 0.1533177685667753 0.8781476890431403 1.0 1.0 3 Q00535,P50570 2
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3461990749037224 0.1523278300620172 0.8789283758300206 1.0 1.0 6 Q9UBI6 1
Copi mediated anterograde transport 0.3016164661156209 0.1507778751442066 0.8801509397914851 1.0 1.0 50 Q96FJ2,Q99747,P53621,P68371,P35606,Q13885,P24390,Q08379,Q9BVA1,O15020,Q92538,O75935,Q13561,Q14203,P04350,Q9Y3Q3,Q9Y678 17
Formation of tc ner pre incision complex 0.2887486754663048 0.1494734214058825 0.8811800803911831 1.0 1.0 22 P30876,P61201,Q93009 3
Thromboxane signalling through tp receptor 0.4413807444737445 0.1468100277523766 0.8832819694500587 1.0 1.0 3 Q9UBI6 1
Maturation of sars cov 2 nucleoprotein 0.3466238271117503 0.1448982357368631 0.8847912194137655 1.0 1.0 5 P49841 1
Activation of bad and translocation to mitochondria 0.3415922014622315 0.1416472658478649 0.8873586305588848 1.0 1.0 6 Q04917,P27348,P61981,P63104,P31946 5
E2f enabled inhibition of pre replication complex formation 0.3447374965125673 0.1408150058727353 0.888016088217426 1.0 1.0 5 P14635 1
O linked glycosylation 0.4361054766734181 0.1377172164807757 0.8904639122700779 1.0 1.0 3 Q10471,Q10472 2
O linked glycosylation of mucins 0.436105476673418 0.1377172164807754 0.8904639122700782 1.0 1.0 3 Q10471,Q10472 2
Beta oxidation of very long chain fatty acids 0.4352941176470448 0.1363515871298157 0.891543344017449 1.0 1.0 3 Q15067,P51659 2
Trna processing in the mitochondrion 0.3646098418064187 0.1352668939423019 0.8924008592766166 1.0 1.0 4 Q7L0Y3 1
Heme biosynthesis 0.4307581279588349 0.1288782571434951 0.8974539814576341 1.0 1.0 3 P22830 1
Resolution of sister chromatid cohesion 0.2984756095119239 0.1234413018141126 0.9017576530298724 1.0 1.0 49 Q15691,P68371,Q13885,P30153,Q9BVA1,O75122,O43264,P14635,P30154,Q8NFH4,Q29RF7,P04350 12
Runx2 regulates bone development 0.4271805273833538 0.1231767502251326 0.901967135982054 1.0 1.0 3 P27361,P28482 2
Negative regulation of nmda receptor mediated neuronal transmission 0.356778938344485 0.1207787994656834 0.9038662427337468 1.0 1.0 4 Q15334,Q14168 2
Pka activation in glucagon signalling 0.424830138187692 0.1195233290331763 0.9048607586191828 1.0 1.0 3 P13861 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.424830138187692 0.1195233290331763 0.9048607586191828 1.0 1.0 3 P13861 1
Pka mediated phosphorylation of creb 0.424830138187692 0.1195233290331763 0.9048607586191828 1.0 1.0 3 P13861 1
Platelet aggregation plug formation 0.354707792207789 0.1171103192707394 0.90677263241314 1.0 1.0 4 P62993,P18031,P41240 3
Integrin signaling 0.354707792207789 0.1171103192707394 0.90677263241314 1.0 1.0 4 P62993,P18031,P41240 3
Mhc class ii antigen presentation 0.2972829029881455 0.1159501003233297 0.9076920891214728 1.0 1.0 49 Q00610,Q96FJ2,P42025,P68371,Q9NSK0,Q13885,Q9BVA1,O15020,O75935,Q13561,Q14203,Q15436,P52732,P04350,O94979,P33176 16
Rac1 gtpase cycle 0.2993840531084592 0.1125991361720603 0.9103483699301436 1.0 1.0 36 Q14185,Q9UQB8,Q7L576 3
Ca dependent events 0.3274165327076133 0.1111638583952987 0.9114864107797384 1.0 1.0 6 P52292,P13861,P28482 3
Ptk6 regulates proteins involved in rna processing 0.5227088402270808 0.1088059156250669 0.9133564316888756 1.0 1.0 2 Q07666 1
Synthesis of leukotrienes lt and eoxins ex 0.5158150851581429 0.1000870821112502 0.9202751908152484 1.0 1.0 2 P09960 1
Metabolism of lipids 0.2916194856199124 0.097418924809731 0.9223937163848408 1.0 1.0 141 P30536,O15121,Q9NPH0,P35790,Q15392,P07602,O43772,Q9BWD1,O95772,Q8N8N7,Q16850,Q15436,Q9BZK7,Q8IV08,P23786 15
Amino acid transport across the plasma membrane 0.4044624746450167 0.0908949516073064 0.9275760616223164 1.0 1.0 3 P08195,Q9H2H9 2
Notch3 intracellular domain regulates transcription 0.4040567951318367 0.0903791633784095 0.9279859141352343 1.0 1.0 3 P42224,Q13573 2
Fgfr2 alternative splicing 0.2754997848209777 0.0884159580668594 0.9295460782642656 1.0 1.0 13 P30876,P52597 2
Apoptotic factor mediated response 0.3119845573890771 0.0821090446634887 0.934560000811421 1.0 1.0 6 P42574,P28482 2
Hs gag degradation 0.4983779399837713 0.0804594717349954 0.9358718285598608 1.0 1.0 2 P54802 1
Trna modification in the mitochondrion 0.3949317389288555 0.0793253078658208 0.9367738769591928 1.0 1.0 3 Q7L0Y3 1
Costimulation by the cd28 family 0.2783573356877259 0.0771805921574853 0.9384798808017878 1.0 1.0 10 P30153 1
Dna damage reversal 0.4935117599351091 0.0755814606402296 0.9397520865339866 1.0 1.0 2 Q6P6C2 1
Sema4d in semaphorin signaling 0.2922041455916737 0.0743838049755479 0.9407049948587292 1.0 1.0 8 P35579,P35580 2
Cell cycle mitotic 0.3335419356264584 0.0737053172110988 0.94124486777717 1.0 1.0 213 P60900,P49720,Q9Y2S7,Q92973,P33991,Q8N1F7,Q13885,Q14566,P12270,P30153,O75122,O43264,O75935,O00231,P30154,Q13561,Q9H1A4,P04350,Q9UJX4,Q8N257,Q9H6D7,P28070,P28072,O43242,Q9UN37,P14635,Q8NFH4,Q9BV73,Q7L590,P28074,O95684,P49721,Q16763,Q96FJ2,P68371,Q01105,Q08379,Q15003,P24941,Q9BVA1,Q86XL3,P11802,P49841,P31350,P42695,Q29RF7,Q99436,Q15691,Q15008,P07437,P40938,Q8IXJ6,Q8NC56,Q99567,Q9UJX3,O43633,P20618,Q9Y619,Q07864,Q14203,Q9Y6X3 61
Serine biosynthesis 0.4882400648823963 0.0705808947877282 0.9437313162356976 1.0 1.0 2 O43175 1
Sars cov 1 infection 0.2679671533555564 0.0657408837177974 0.9475841222985332 1.0 1.0 12 P49841 1
Map3k8 tpl2 dependent mapk1 3 activation 0.3813387423934953 0.0647544663682196 0.9483694958905092 1.0 1.0 3 Q02750,P63208 2
Activation of kainate receptors upon glutamate binding 0.378316151115918 0.0618123392909569 0.9507122769461882 1.0 1.0 3 Q9UBI6 1
Vitamin b5 pantothenate metabolism 0.3084415584415546 0.0525597550875725 0.9580826834097792 1.0 1.0 4 Q9NVE7,Q9NRN7,P49327 3
Hdms demethylate histones 0.2864774161840296 0.0504943276152911 0.959728469547678 1.0 1.0 7 Q8NB78,Q7LBC6 2
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.2909923345641625 0.0504544796055461 0.959760223184835 1.0 1.0 5 Q15067,O95864,P33121 3
Caspase mediated cleavage of cytoskeletal proteins 0.2865243204068815 0.0434813010735785 0.965317870009208 1.0 1.0 6 P35611,P08670,P42574 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.2955860386590681 0.0401867426565451 0.9679442469203454 1.0 1.0 4 Q99570,O14654 2
Synthesis of pips at the early endosome membrane 0.4432278994322804 0.0387487164762443 0.9690907324199128 1.0 1.0 2 Q99570 1
G1 s specific transcription 0.2647417649451052 0.0373029721534187 0.9702434357081025 1.0 1.0 9 Q09028,P09884,P04183,P06493,P12004,Q9Y619,Q13547,P31350 8
Translesion synthesis by polh 0.259444049776837 0.0352573703618899 0.9718745157024098 1.0 1.0 10 Q8TAT6,P27694,P40938,Q92890 4
Insulin processing 0.2784524645558117 0.0335634435519802 0.973225273652888 1.0 1.0 6 Q8IYI6 1
Metabolism of nucleotides 0.2815039904476803 0.0276296489180484 0.977957534270764 1.0 1.0 36 Q16881,Q9Y3Z3,P30520,P22102,P55263,P00813,P22392,P17812,P31350,Q06203 10
Collagen biosynthesis and modifying enzymes 0.2590408979735694 0.0272629890023335 0.9782499763858096 1.0 1.0 9 Q32P28,O75718,Q8NBJ5,O00469 4
Signaling by fgfr2 0.2509445176008097 0.0268687827456778 0.9785643922840406 1.0 1.0 19 P30153,P30876,P52597 3
Signaling by fgfr 0.2509445176008097 0.0268687827456778 0.9785643922840406 1.0 1.0 19 P30153,P30876,P52597 3
Pentose phosphate pathway 0.2689963429500194 0.0258778561017891 0.97935476240221 1.0 1.0 7 P52209,O95336,P37837,P29401,Q96G03,P11908 6
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.2540632180556772 0.0250683095062018 0.9800004775852936 1.0 1.0 10 Q9NQT5,Q92973 2
Depolymerisation of the nuclear lamina 0.2574056090274281 0.024526737170547 0.9804324569490106 1.0 1.0 9 P14635 1
Plasma lipoprotein assembly 0.3880778588807776 0.0200373578065804 0.9840135713210874 1.0 1.0 2 P07237 1
Death receptor signalling 0.2478505971479231 0.0198953321958058 0.984126868777522 1.0 1.0 17 P42575 1
Notch4 activation and transmission of signal to the nucleus 0.3852392538523912 0.0194924915151951 0.9844482268094464 1.0 1.0 2 Q92542 1
Regulation of bach1 activity 0.381184103811839 0.0187672694909875 0.985026764384768 1.0 1.0 2 P63208 1
Fbxw7 mutants and notch1 in cancer 0.381184103811839 0.0187672694909875 0.985026764384768 1.0 1.0 2 P63208 1
Copii mediated vesicle transport 0.2585025601879758 0.0181473784206568 0.9855212816497811 1.0 1.0 23 Q15436 1
Translation of sars cov 1 structural proteins 0.2616822429906563 0.0172418310326221 0.9862436908034328 1.0 1.0 7 Q13724,P49840,Q14697,P49841,Q10472,P14314 6
Grb2 sos provides linkage to mapk signaling for integrins 0.3544201135442018 0.0153010513156756 0.9877920037534602 1.0 1.0 2 P62993 1
Mapk1 erk2 activation 0.2935252621297958 0.0150418418931416 0.9879987991484296 1.0 1.0 3 P28482 1
Sumo is conjugated to e1 uba2 sae1 0.3483373884833768 0.0147727816825745 0.9882134542832102 1.0 1.0 2 Q9UBE0 1
Processing and activation of sumo 0.3483373884833768 0.0147727816825745 0.9882134542832102 1.0 1.0 2 Q9UBE0 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.3483373884833768 0.0147727816825745 0.9882134542832102 1.0 1.0 2 Q9UBE0 1
Abc transporters in lipid homeostasis 0.2972424979724286 0.0125624894156144 0.9899768472866044 1.0 1.0 2 P40855 1
Clathrin mediated endocytosis 0.2810018447564125 0.0116615382878114 0.9906956495308128 1.0 1.0 43 P61201,Q14C86,O43493,Q14108 4
Oncogenic mapk signaling 0.2585469076267876 0.0104991351756735 0.9916230560428207 1.0 1.0 24 P51114,Q6WCQ1,Q7Z2W4,Q9NRY5,P21359,P28482 6
Interleukin 4 and interleukin 13 signaling 0.2413966303768963 0.0096976204761993 0.9922625396224564 1.0 1.0 11 P40763 1
G alpha 12 13 signalling events 0.2499346144564581 0.0052899591294595 0.9957792429687122 1.0 1.0 7 Q9UBI6 1
Interferon signaling 0.2702284055546026 0.0034747895180582 0.9972275246707224 1.0 1.0 56 P52292,Q9Y3Z3,O15344,O75694,Q8N1F7,P49792,P12270,P10321,Q8WUM0,Q9Y4X5,P19474,Q92621,Q8NFH4,O00629,P42224,P29372,Q04637,P04439,P37198,Q99567,Q13325 21