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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/basic/plot_0.png +3 -0
  4. interpro_active_site/consensus.joblib +3 -0
  5. interpro_active_site/df_merge.tsv +1 -0
  6. interpro_active_site/metrics.json +7 -0
  7. interpro_active_site/paths.json +1 -0
  8. interpro_active_site/result.tsv +7 -0
  9. interpro_active_site/selections.json +1 -0
  10. interpro_binding_site/advanced/idx2term.json +1 -0
  11. interpro_binding_site/basic/idx2term.json +1 -0
  12. interpro_binding_site/consensus.joblib +3 -0
  13. interpro_binding_site/df_merge.tsv +1 -0
  14. interpro_binding_site/metrics.json +7 -0
  15. interpro_binding_site/paths.json +1 -0
  16. interpro_binding_site/result.tsv +2 -0
  17. interpro_binding_site/selections.json +1 -0
  18. interpro_conserved_site/advanced/idx2term.json +1 -0
  19. interpro_conserved_site/basic/idx2term.json +1 -0
  20. interpro_conserved_site/basic/plot_0.png +3 -0
  21. interpro_conserved_site/basic/plot_1.png +3 -0
  22. interpro_conserved_site/consensus.joblib +3 -0
  23. interpro_conserved_site/df_merge.tsv +1 -0
  24. interpro_conserved_site/metrics.json +7 -0
  25. interpro_conserved_site/paths.json +1 -0
  26. interpro_conserved_site/result.tsv +22 -0
  27. interpro_conserved_site/selections.json +1 -0
  28. interpro_domain/advanced/idx2term.json +1 -0
  29. interpro_domain/basic/idx2term.json +1 -0
  30. interpro_domain/basic/plot_0.png +3 -0
  31. interpro_domain/basic/plot_1.png +3 -0
  32. interpro_domain/basic/plot_2.png +3 -0
  33. interpro_domain/basic/plot_3.png +3 -0
  34. interpro_domain/basic/plot_4.png +3 -0
  35. interpro_domain/basic/plot_5.png +3 -0
  36. interpro_domain/basic/plot_6.png +3 -0
  37. interpro_domain/basic/plot_7.png +3 -0
  38. interpro_domain/consensus.joblib +3 -0
  39. interpro_domain/df_merge.tsv +2 -0
  40. interpro_domain/metrics.json +7 -0
  41. interpro_domain/paths.json +1 -0
  42. interpro_domain/result.tsv +181 -0
  43. interpro_domain/selections.json +0 -0
  44. interpro_family/advanced/idx2term.json +1 -0
  45. interpro_family/basic/idx2term.json +1 -0
  46. interpro_family/basic/plot_0.png +3 -0
  47. interpro_family/consensus.joblib +3 -0
  48. interpro_family/df_merge.tsv +1 -0
  49. interpro_family/metrics.json +7 -0
  50. interpro_family/paths.json +1 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
interpro_active_site/basic/plot_0.png ADDED

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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 2063,
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+ "annotations_size": 47,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.1914893617021276
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+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C411/C411_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Protein-tyrosine phosphatase, active site [IPR016130] 0.7068737542827128 1.125508219678034 0.2603737360754183 0.999999302443727 0.6926018565787789 3 P51452 1
3
+ Thiolase, active site [IPR020610] 0.41700308332475 0.2713634770468719 0.786111489567179 1.0 0.9949615225954882 4 P42765 1
4
+ ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.341994062716974 0.1048514485609164 0.9164936849572336 1.0 0.9949615225954882 4 P06576 1
5
+ ATP:guanido phosphotransferase active site [IPR022415] 0.4051431344007802 0.0143862889822177 0.9885217980668106 1.0 0.9949615225954882 2 P12277 1
6
+ Peptidase S9, serine active site [IPR002471] 0.3813682678311511 0.01152580280925 0.9908039434951136 1.0 0.9949615225954882 2 P13798 1
7
+ Serine/threonine-protein kinase, active site [IPR008271] 0.3327346808137363 0.0063148369310011 0.9949615225954882 1.0 0.9949615225954882 31 Q99570,P24941,P17612,P06493,Q96KB5,P28482,P51812 7
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
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+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK4", "CAPN1", "CASP3", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSNK1A1", "CSNK2A2", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "UBA1", "UBA2", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["ACAA2", "APEH", "ATP5B", "CDK1", "CDK2", "CKB", "DUSP3", "MAPK1", "PBK", "PIK3R4", "PRKACA", "RPS6KA3"]}
interpro_binding_site/advanced/idx2term.json ADDED
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+ {}
interpro_binding_site/basic/idx2term.json ADDED
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interpro_binding_site/consensus.joblib ADDED
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interpro_binding_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 2063,
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+ "annotations_size": 26,
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+ "title": "Average number of proteins per term",
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+ "value": 3.9615384615384617
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+ }
interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C411/C411_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838] 0.3061620572537581 0.0084042233593696 0.993294478872357 1.0 1.0 2 P17174 1
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "APOBEC3C", "CALM3", "CALU", "CAMK4", "CAPN1", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EIF2AK2", "FKBP10", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PGD", "PKN2", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK1", "RPS6KA3", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SPTAN1", "SRI", "SRPK1", "STK26", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UQCRC2", "VRK1"], "leading_proteins": ["GOT1"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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+ {}
interpro_conserved_site/basic/idx2term.json ADDED
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+ {"0": "Kinesin motor domain, conserved site [IPR019821]", "1": "Mini-chromosome maintenance, conserved site [IPR018525]"}
interpro_conserved_site/basic/plot_0.png ADDED

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interpro_conserved_site/basic/plot_1.png ADDED

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interpro_conserved_site/consensus.joblib ADDED
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interpro_conserved_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_conserved_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "annotations_size": 229,
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+ "title": "Average number of proteins per term",
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+ "value": 2.4366812227074237
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C411/C411_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,22 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Phosphofructokinase, conserved site [IPR015912] 0.8824107307754159 1.8357122097951049 0.0664002311999343 0.9999998531721545 0.6128312080757938 3 P08237 1
3
+ Intermediate filament protein, conserved site [IPR018039] 0.606108715744746 1.4710229173163174 0.1412849192601655 0.9999999999999992 0.637826772254301 7 Q16352,P07197 2
4
+ Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364] 0.9519650655021856 1.2116608984793136 0.2256422126807211 1.0 0.7381723814840735 2 Q8N4Q0 1
5
+ Kinesin motor domain, conserved site [IPR019821] 0.558323970436632 1.1612109931762131 0.2455561052412718 1.0 0.7518398619415192 9 P52732,Q14807,Q99661,O95235,O95239 5
6
+ Sugar transporter, conserved site [IPR005829] 0.8694808345463384 0.9144154911267556 0.360498564966752 1.0 0.8981089876983342 2 Q7L0J3 1
7
+ Polyamine biosynthesis domain, conserved site [IPR030373] 0.8660844250363918 0.9024584327378222 0.3668133929348625 1.0 0.8981089876983342 2 P19623 1
8
+ Zinc finger, RING-type, conserved site [IPR017907] 0.5021133502212798 0.8521197326678933 0.394147640901934 1.0 0.9402063517348218 10 Q9UPN9,O15164,Q99496,O15344 4
9
+ Actinin-type actin-binding domain, conserved site [IPR001589] 0.5119060538457846 0.7769753414435823 0.4371733186819848 1.0 0.946832103454261 14 P46939,O15020 2
10
+ Thioredoxin, conserved site [IPR017937] 0.4417118164528431 0.5993930295489418 0.5489108241178777 1.0 0.946832103454261 6 Q9H3N1,P07237 2
11
+ DnaJ domain, conserved site [IPR018253] 0.4642290904637054 0.5544698058228469 0.5792573642524836 1.0 0.946832103454261 5 P25685 1
12
+ RNA polymerase, beta subunit, conserved site [IPR007121] 0.7612809315866165 0.5539426547553353 0.5796180920064085 1.0 0.946832103454261 2 P30876 1
13
+ Mini-chromosome maintenance, conserved site [IPR018525] 0.4297520661157077 0.5466862306559345 0.5845943155763931 1.0 0.946832103454261 6 Q14566,P33992,P25205,P33991,P49736 5
14
+ Heat shock protein 70, conserved site [IPR018181] 0.4123718966799787 0.5244263432418443 0.5999820379500065 1.0 0.946832103454261 7 P0DMV9,P34932 2
15
+ Zinc finger, PHD-type, conserved site [IPR019786] 0.4334871157857274 0.5099837254080968 0.6100628635570979 1.0 0.946832103454261 11 Q9UPN9 1
16
+ Mitogen-activated protein (MAP) kinase, conserved site [IPR003527] 0.7190684133915677 0.4300268605886838 0.6671761021809195 1.0 0.9653410939645108 2 P28482 1
17
+ DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.6627850557981589 0.2866105231544268 0.7744105560282246 1.0 0.9708542148437228 2 P09884 1
18
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.3614640836113422 0.2794742588457217 0.7798808897893914 1.0 0.9708542148437228 6 Q9P2W9,O43752,Q12846 3
19
+ Thiolase, conserved site [IPR020613] 0.3732202908239744 0.2311331452825847 0.8172113659691087 1.0 0.9708542148437228 5 P42765,Q9BWD1 2
20
+ FERM conserved site [IPR019747] 0.3259738049618133 0.2014955574709174 0.8403111028238615 1.0 0.9708542148437228 7 Q9Y2J2 1
21
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.6152353226589085 0.1889826122612337 0.8501064446343696 1.0 0.9708542148437228 2 Q16836 1
22
+ Ribosomal protein L24e, conserved site [IPR023442] 0.467734109655512 0.0318005758552299 0.974631087403904 1.0 0.9973864309162426 2 P83731 1
interpro_conserved_site/selections.json ADDED
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+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Annexin repeat, conserved site [IPR018252]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AHCY", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA2", "ANXA6", "ANXA7", "AP2M1", "AP2S1", "AP3M1", "APEX1", "ARHGEF7", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BLM", "BOP1", "BPTF", "BRD2", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CETN2", "CHAF1B", "CHD1", "CHD4", "CMPK1", "COLEC12", "COPA", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CYP51A1", "DCAF7", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJB1", "DNAJC1", "DNAJC11", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DST", "DTYMK", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A3", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "ERCC2", "ETFA", "ETFB", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GNPDA1", "GNS", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "IQGAP1", "IVD", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP43", "OSBP", "OSBPL9", "P4HB", "PAICS", "PAK1IP1", "PBRM1", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF3", "PHGDH", "PHIP", "PLEC", "PLOD1", "PLRG1", "PLS1", "PLS3", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPIF", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP4", "RCL1", "RDX", "RNF2", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPTBN1", "SPTBN2", "SRM", "STMN1", "STOM", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TMBIM6", "TMX1", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TSFM", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC5", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP24", "USP48", "USP5", "USP7", "USP9X", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACAA2", "ACAT2", "DNAJB1", "EPB41L3", "HADH", "HSPA1B", "HSPA4", "INA", "KIF11", "KIF20A", "KIF22", "KIF2C", "KIF4A", "MAPK1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MID1", "NEFM", "P4HB", "PFKM", "POLA1", "POLR2B", "RNF2", "RPL24", "SPTBN2", "SRM", "STX18", "STX4", "STX6", "SV2A", "TMX1", "TRIM24", "TRIM33", "UTRN", "ZADH2"]}
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
2
+ B-box-type zinc finger [IPR000315] 2 5 2.1938701741947626 0.0282447441405855 2.150485436893204 6.019417475728155 0.1378906185367559 0.5071478683401887 1.8477682043932235 1.6174448417195804 0.9644160769127244 0.3051430714909308 1.0 0.2827159209662828 0.2012424218570439 0.2308247548684397
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2063,
4
+ "annotations_size": 1959,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.0040837161817255
7
+ }
interpro_domain/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C411/C411_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,181 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ B-box-type zinc finger [IPR000315] 0.8284368975798985 2.1938701741947626 0.0282447441405855 1.0 0.5467418922072542 5 Q9UPN9,O15344 2
3
+ B-box, C-terminal [IPR003649] 0.8356309188628911 1.9526364492053 0.0508626889502383 1.0 0.5467418922072542 4 Q9UPN9,O15344 2
4
+ Alcohol dehydrogenase, N-terminal [IPR013154] 0.8868105406438318 1.853235674509172 0.0638485864724751 1.0 0.5510104885444002 3 Q8N4Q0 1
5
+ Phosphofructokinase domain [IPR000023] 0.8824107307754159 1.8357122097951049 0.0664002311999343 1.0 0.5517687229915528 3 P08237 1
6
+ Intermediate filament head, DNA-binding domain [IPR006821] 0.8774701569384884 1.8160085430559467 0.0693690616530053 1.0 0.5573541680013557 3 P07197 1
7
+ Band 7 domain [IPR001107] 0.6740863871812794 1.8083850943425492 0.0705465861816201 1.0 0.5573541680013557 7 Q9UJZ1,P27105 2
8
+ HECT domain [IPR000569] 0.7310651465363467 1.7610101277772152 0.0782366888430132 1.0 0.5733540080104528 5 Q9ULT8,Q7Z6Z7,Q05086 3
9
+ LSM domain, eukaryotic/archaea-type [IPR001163] 0.6691836572308344 1.7017053963378022 0.0888106083201707 1.0 0.5782083648487218 6 P62304,P62310,P62314 3
10
+ Myb domain [IPR017930] 0.6657066863794392 1.6848157142275952 0.0920241321289663 1.0 0.5804973714031904 6 Q96KC8,Q8TAQ2,Q9UKL0 3
11
+ BRCT domain [IPR001357] 0.6430076509420082 1.6550886087860108 0.0979065252095305 1.0 0.5804973714031904 7 Q14676 1
12
+ WW domain [IPR001202] 0.6544660558697255 1.6300776128870638 0.1030850945603196 1.0 0.5813701630020462 6 O75400,Q96J02,P46939 3
13
+ PUA domain [IPR002478] 0.813559985199171 1.5589132166331918 0.1190169217342798 1.0 0.6121518813445349 3 Q9Y221 1
14
+ Intermediate filament, rod domain [IPR039008] 0.606108715744746 1.4710229173163174 0.1412849192601655 1.0 0.6248322812617495 7 Q16352,P07197 2
15
+ Polyketide synthase, enoylreductase domain [IPR020843] 0.7838850361097079 1.4384832926422726 0.1502969745824918 1.0 0.6273083124027284 3 Q8N4Q0 1
16
+ AGC-kinase, C-terminal [IPR000961] 0.7090820786789661 1.4164342696508534 0.1566483962454641 1.0 0.6285767825683675 4 Q16513,P17612,P51812 3
17
+ Myosin, N-terminal, SH3-like [IPR004009] 0.649670522614683 1.3878508803269185 0.1651824576994887 1.0 0.6407770982837592 5 Q9UM54,Q9Y4I1 2
18
+ SWIRM domain [IPR007526] 0.6901743644737605 1.335114539679788 0.1818388614449122 1.0 0.6418021008649449 4 Q8TAQ2,Q8NB78 2
19
+ Desmoplakin, spectrin-like domain [IPR041573] 0.6839528602718037 1.3083374071557856 0.1907588926654368 1.0 0.6418021008649449 4 Q03001,P15924 2
20
+ Desmoplakin, SH3 domain [IPR041615] 0.6839528602718037 1.3083374071557856 0.1907588926654368 1.0 0.6418021008649449 4 Q03001,P15924 2
21
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.9737991266375547 1.2917573045220996 0.1964412054379702 1.0 0.6498316173709872 2 Q9NUQ9 1
22
+ Major facilitator superfamily domain [IPR020846] 0.7341855996932423 1.2362977112110498 0.2163479215761972 1.0 0.6632638159120036 3 Q7L0J3 1
23
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.5576855771478895 1.22744543181442 0.219655219561941 1.0 0.6692666389780839 7 P98194,P23634,Q9HD20 3
24
+ Forkhead-associated (FHA) domain [IPR000253] 0.6022036755491947 1.1680824076164982 0.2427735258066499 1.0 0.697153288380985 5 Q12756,P55196,Q14676 3
25
+ Kinesin motor domain [IPR001752] 0.558323970436632 1.1612109931762131 0.2455561052412718 1.0 0.6991924566390283 9 P52732,Q14807,Q99661,O95235,O95239 5
26
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.7068737542827128 1.125508219678034 0.2603737360754183 1.0 0.7245343025166826 3 P51452 1
27
+ MRG domain [IPR026541] 0.9262493934983022 1.1178806052639223 0.2636179894327615 1.0 0.7304492804791792 2 Q9UBU8 1
28
+ RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.9155749636099 1.0791907942470182 0.2805026826286356 1.0 0.7458593759455655 2 Q9UPN9 1
29
+ SANT domain [IPR017884] 0.5348550247142925 1.0783099608118198 0.2808954533395664 1.0 0.7458593759455655 8 Q8TAQ2,Q9UKL0 2
30
+ Immunoglobulin subtype [IPR003599] 0.5813565928187044 1.0718179541664232 0.2838018072324979 1.0 0.7472684682371821 5 Q13308,Q8WX93 2
31
+ SANT/Myb domain [IPR001005] 0.5400420905223766 1.0370012805402211 0.2997352603705374 1.0 0.762229309720415 10 Q96L91,Q8TAQ2,Q9UKL0 3
32
+ Immunoglobulin I-set [IPR013098] 0.9034449296458048 1.0354352356927197 0.3004656974033228 1.0 0.762229309720415 2 Q8WX93 1
33
+ Phosphoribosyltransferase domain [IPR000836] 0.5726542073888043 1.0317825225420847 0.3021740085488016 1.0 0.762833611787503 5 P11172 1
34
+ Phox homology [IPR001683] 0.612452577000786 1.0017975612257806 0.3164413753403374 1.0 0.7729534342789539 4 Q9Y5X1 1
35
+ Ran binding domain [IPR000156] 0.6749354417285638 0.9969536785158268 0.3187869945990971 1.0 0.7757810216392934 3 Q9UKX7 1
36
+ C2 domain [IPR000008] 0.5589473427928706 0.96898736664465 0.3325514924875321 1.0 0.7902174443276656 5 Q96J02,Q86YQ8 2
37
+ Spermidine synthase, tetramerisation domain [IPR035246] 0.8660844250363918 0.9024584327378222 0.3668133929348625 1.0 0.8297776405997639 2 P19623 1
38
+ Polyamine biosynthesis domain [IPR030374] 0.8660844250363918 0.9024584327378222 0.3668133929348625 1.0 0.8297776405997639 2 P19623 1
39
+ Immunoglobulin-like domain [IPR007110] 0.4842081051911933 0.8606674948732665 0.3894212005861452 1.0 0.8590947431849759 7 Q13308,Q8WX93 2
40
+ Condensin complex subunit 1, C-terminal [IPR032682] 0.8495875788452272 0.8448292305939837 0.3982061917231356 1.0 0.864145524343151 2 P42695 1
41
+ Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.5230535124599798 0.8068743128146778 0.4197388994231836 1.0 0.8677442091341787 5 P23634 1
42
+ Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.5230535124599798 0.8068743128146778 0.4197388994231836 1.0 0.8677442091341787 5 P23634 1
43
+ Peptidase S8/S53 domain [IPR000209] 0.8369723435225691 0.8013151120562733 0.4229492443602543 1.0 0.8677442091341787 2 O14773 1
44
+ Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.8364871421640006 0.7996519898161288 0.4239124564542997 1.0 0.8677442091341787 2 Q13243 1
45
+ Extended PHD (ePHD) domain [IPR034732] 0.8330907326540516 0.7880329750823928 0.430677418024481 1.0 0.8677637740039392 2 Q8IWS0 1
46
+ Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.4815209593624859 0.7829345502850406 0.4336655471784512 1.0 0.8677740622294033 6 Q15031,Q5ST30 2
47
+ Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.4815209593624859 0.7829345502850406 0.4336655471784512 1.0 0.8677740622294033 6 Q15031,Q5ST30 2
48
+ GAR domain [IPR003108] 0.830664725861237 0.7797585986880473 0.4355329797889307 1.0 0.8706215381699135 2 Q03001 1
49
+ FAD linked oxidase, N-terminal [IPR006094] 0.8267831149927236 0.7665639980853831 0.4433407875934132 1.0 0.8790532417970611 2 Q15392 1
50
+ FAD-binding domain, PCMH-type [IPR016166] 0.8267831149927236 0.7665639980853831 0.4433407875934132 1.0 0.8790532417970611 2 Q15392 1
51
+ MIT domain [IPR007330] 0.8229015041242131 0.7534256300591015 0.4511941860063655 1.0 0.8865490575591476 2 O75351 1
52
+ SET domain [IPR001214] 0.5515175619923389 0.7479148571505612 0.4545115154501187 1.0 0.8893271456294839 4 Q03164,Q96KQ7 2
53
+ La-type HTH domain [IPR006630] 0.4956607568033326 0.6866611895980467 0.4922962592447346 1.0 0.9194483914593488 5 Q6PKG0,P05455,Q92615 3
54
+ Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786] 0.4595594094321635 0.6803298783437155 0.496295610048177 1.0 0.9215638151343742 6 Q709F0 1
55
+ Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075] 0.4595594094321635 0.6803298783437155 0.496295610048177 1.0 0.9215638151343742 6 Q709F0 1
56
+ VHS domain [IPR002014] 0.797671033478897 0.6695268725024568 0.5031594445977761 1.0 0.9229559921269423 2 Q9UJY4 1
57
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.4357992301678011 0.6297640468561169 0.5288489718133222 1.0 0.9456756147054156 7 Q709F0 1
58
+ Dilute domain [IPR002710] 0.7850557981562344 0.6286647588913623 0.5295685543106294 1.0 0.9456926143067668 2 Q9Y4I1 1
59
+ Xrn1, helical domain [IPR041412] 0.7831149927219868 0.6224491830499768 0.5336465486323667 1.0 0.9467807920645912 2 Q8IZH2 1
60
+ Putative 5-3 exonuclease [IPR004859] 0.7831149927219868 0.6224491830499768 0.5336465486323667 1.0 0.9467807920645912 2 Q8IZH2 1
61
+ Methyltransferase type 11 [IPR013216] 0.7811741872877304 0.6162532663434004 0.5377273777014635 1.0 0.9467807920645912 2 Q8N6R0 1
62
+ Importin-beta, N-terminal domain [IPR001494] 0.4572005174621188 0.6132811656997345 0.5396904446966431 1.0 0.9467807920645912 11 Q8TEX9 1
63
+ Zinc finger, double-stranded RNA binding [IPR022755] 0.573449222282716 0.6070877550540421 0.5437926759512377 1.0 0.9467807920645912 3 Q9UKJ3 1
64
+ Translation initiation factor, beta propellor-like domain [IPR013979] 0.5731428761378223 0.605982663069073 0.5445262657316268 1.0 0.9467807920645912 3 P55884 1
65
+ Pleckstrin homology domain [IPR001849] 0.4600689588861315 0.598539552935775 0.5494799755065287 1.0 0.9467807920645912 12 O15020 1
66
+ DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.7612809315866165 0.5539426547553353 0.5796180920064085 1.0 0.9576602891628118 2 P30876 1
67
+ RNA polymerase Rpb2, domain 3 [IPR007645] 0.7612809315866165 0.5539426547553353 0.5796180920064085 1.0 0.9576602891628118 2 P30876 1
68
+ RNA polymerase, beta subunit, protrusion [IPR007644] 0.7612809315866165 0.5539426547553353 0.5796180920064085 1.0 0.9576602891628118 2 P30876 1
69
+ RNA polymerase Rpb2, domain 2 [IPR007642] 0.7612809315866165 0.5539426547553353 0.5796180920064085 1.0 0.9576602891628118 2 P30876 1
70
+ RNA polymerase Rpb2, domain 7 [IPR007641] 0.7612809315866165 0.5539426547553353 0.5796180920064085 1.0 0.9576602891628118 2 P30876 1
71
+ Immunoglobulin subtype 2 [IPR003598] 0.5005061977196915 0.5483336175279683 0.5834628482285384 1.0 0.9576602891628118 4 Q8WX93 1
72
+ MCM OB domain [IPR033762] 0.4297520661157077 0.5466862306559345 0.5845943155763931 1.0 0.9576602891628118 6 Q14566,P33992,P25205,P33991,P49736 5
73
+ MCM, AAA-lid domain [IPR041562] 0.4297520661157077 0.5466862306559345 0.5845943155763931 1.0 0.9576602891628118 6 Q14566,P33992,P25205,P33991,P49736 5
74
+ MCM N-terminal domain [IPR027925] 0.4297520661157077 0.5466862306559345 0.5845943155763931 1.0 0.9576602891628118 6 Q14566,P33992,P25205,P33991,P49736 5
75
+ MCM domain [IPR001208] 0.4297520661157077 0.5466862306559345 0.5845943155763931 1.0 0.9576602891628118 6 Q14566,P33992,P25205,P33991,P49736 5
76
+ von Willebrand factor, type A [IPR002035] 0.4293863490875128 0.5450962569426998 0.5856873169128338 1.0 0.9576602891628118 6 Q86YQ8 1
77
+ Transcription factor IIS, N-terminal [IPR017923] 0.7520621057738963 0.5258596587417184 0.598985719863457 1.0 0.9624170119809478 2 P23193 1
78
+ Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617] 0.7520621057738963 0.5258596587417184 0.598985719863457 1.0 0.9624170119809478 2 P23193 1
79
+ Protein kinase, C-terminal [IPR017892] 0.7442988840368814 0.5026315172560558 0.6152233660942872 1.0 0.9641780593429669 2 P51812 1
80
+ FF domain [IPR002713] 0.7418728772440556 0.4954547384797906 0.6202791638641221 1.0 0.967268350277769 2 O75400 1
81
+ Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.5407404632122453 0.4927766971064394 0.6221703778561547 1.0 0.967268350277769 3 Q9H0H5 1
82
+ Amine oxidase [IPR002937] 0.7375060650169871 0.4826377911008483 0.6293529410368273 1.0 0.9707871100808196 2 Q8NB78 1
83
+ SAP domain [IPR003034] 0.4272607782658846 0.4591104664673106 0.6461548409615276 1.0 0.9775836952294586 12 P35659,Q8IX12 2
84
+ SMCs flexible hinge [IPR010935] 0.4392179131096076 0.4553149154883478 0.6488826971888226 1.0 0.9783961678133632 5 Q9NTJ3,A6NHR9,Q14683 3
85
+ JmjC domain [IPR003347] 0.7268316351285807 0.4518739994779678 0.6513597562836047 1.0 0.9783961678133632 2 Q7LBC6 1
86
+ SH2 domain [IPR000980] 0.4065662265886373 0.4487896254111805 0.6535834234321884 1.0 0.9783961678133632 6 P46109 1
87
+ Ancestral coatomer element 1, Sec16/Sec31 [IPR024298] 0.7171276079573108 0.4246368717589977 0.6711014097451948 1.0 0.9803401617504968 2 O94979 1
88
+ Zinc finger C2H2-type [IPR013087] 0.412506375000796 0.4237562161873283 0.6717436123674108 1.0 0.9803401617504968 11 O95785,Q68CP9 2
89
+ Calponin homology domain [IPR001715] 0.4601914557646731 0.4043634123422208 0.685945501034432 1.0 0.9803401617504968 20 Q69YQ0,P46939,O15020 3
90
+ HR1 rho-binding domain [IPR011072] 0.7083939835031543 0.4007484829752007 0.6886053114879112 1.0 0.9803401617504968 2 Q16513 1
91
+ JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3828392962989733 0.4005466343352695 0.6887539426064899 1.0 0.9803401617504968 7 O15372,Q92905 2
92
+ DNA mismatch repair protein MutS, clamp [IPR007861] 0.7079087821445904 0.3994392595137828 0.6895695710342897 1.0 0.9803401617504968 2 P43246 1
93
+ PDZ domain [IPR001478] 0.4060921862030699 0.3985365747248765 0.6902347035957312 1.0 0.9803401617504968 11 Q14160,Q07157,O00151,Q00013,Q09666,Q9NZW5,P55196 7
94
+ Immunoglobulin V-set domain [IPR013106] 0.705967976710344 0.3942215537402478 0.6934174739555417 1.0 0.9803401617504968 2 Q92692 1
95
+ CD80-like, immunoglobulin C2-set [IPR013162] 0.705967976710344 0.3942215537402478 0.6934174739555417 1.0 0.9803401617504968 2 Q92692 1
96
+ Alanyl-tRNA synthetase, class IIc, core domain [IPR018165] 0.5040607791699305 0.3752289853055813 0.7074901752629592 1.0 0.9803401617504968 3 Q9BTE6 1
97
+ GYF domain [IPR003169] 0.6943231441048052 0.3635740604865851 0.7161760997391318 1.0 0.9803401617504968 2 O95400 1
98
+ RecF/RecN/SMC, N-terminal [IPR003395] 0.4130223517978559 0.3589475607213568 0.7196343189485557 1.0 0.9803401617504968 5 Q9NTJ3,Q14683,O95347,Q96SB8 4
99
+ LIS1 homology motif [IPR006594] 0.4105901401257999 0.3504506583257382 0.7260005139588552 1.0 0.9803401617504968 5 Q14978,Q9Y4B6,O95684 3
100
+ MPN domain [IPR037518] 0.374850763610968 0.3466773097639009 0.7288337584566364 1.0 0.9803401617504968 8 O15372,Q92905 2
101
+ Replication factor C, C-terminal [IPR013748] 0.6870451237263492 0.3450106000669347 0.7300864017665065 1.0 0.9803401617504968 2 P35249 1
102
+ GHMP kinase N-terminal domain [IPR006204] 0.6783114992721999 0.3233579236827517 0.7464241913041392 1.0 0.9803401617504968 2 P53602 1
103
+ DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.6627850557981589 0.2866105231544268 0.7744105560282246 1.0 0.9803401617504968 2 P09884 1
104
+ DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.6627850557981589 0.2866105231544268 0.7744105560282246 1.0 0.9803401617504968 2 P09884 1
105
+ Disulphide isomerase [IPR005788] 0.3882410106899951 0.2764270750349351 0.7822200636758982 1.0 0.9803401617504968 5 Q8NBS9,P30101,Q15084,P07237 4
106
+ TRASH domain [IPR011017] 0.4679611650485403 0.2734282412633574 0.7845240462112033 1.0 0.9803401617504968 3 Q5VZL5,P83731 2
107
+ 2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041] 0.6506550218340676 0.2595199164469843 0.795234117179676 1.0 0.9803401617504968 2 P28331 1
108
+ FERM, N-terminal [IPR018979] 0.3533033082992177 0.2524908913591074 0.8006616537331595 1.0 0.9803401617504968 6 Q9Y2J2 1
109
+ FERM, C-terminal PH-like domain [IPR018980] 0.3533033082992177 0.2524908913591074 0.8006616537331595 1.0 0.9803401617504968 6 Q9Y2J2 1
110
+ SWAP/Surp [IPR000061] 0.3500265407369692 0.2420117804956582 0.8087710350117763 1.0 0.9803401617504968 6 Q12872 1
111
+ STAT transcription factor, DNA-binding [IPR013801] 0.6414361960213549 0.2399137053601852 0.8103971557694645 1.0 0.9803401617504968 2 P40763 1
112
+ STAT transcription factor, protein interaction [IPR013799] 0.6414361960213549 0.2399137053601852 0.8103971557694645 1.0 0.9803401617504968 2 P40763 1
113
+ STAT transcription factor, all-alpha domain [IPR013800] 0.6414361960213549 0.2399137053601852 0.8103971557694645 1.0 0.9803401617504968 2 P40763 1
114
+ Thiolase, N-terminal [IPR020616] 0.3732202908239744 0.2311331452825847 0.8172113659691087 1.0 0.9803401617504968 5 P42765,Q9BWD1 2
115
+ Thiolase, C-terminal [IPR020617] 0.3732202908239744 0.2311331452825847 0.8172113659691087 1.0 0.9803401617504968 5 P42765,Q9BWD1 2
116
+ Clp ATPase, C-terminal [IPR019489] 0.6327025715672047 0.2221405991213567 0.8242044337753127 1.0 0.9803401617504968 2 O76031 1
117
+ DnaJ domain [IPR001623] 0.3501742144116533 0.2070196746735687 0.8359944931589112 1.0 0.9803401617504968 11 P25685,Q13217 2
118
+ FERM domain [IPR000299] 0.3259738049618133 0.2014955574709174 0.8403111028238615 1.0 0.9803401617504968 7 Q9Y2J2 1
119
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.6152353226589085 0.1889826122612337 0.8501064446343696 1.0 0.9803401617504968 2 Q16836 1
120
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.6152353226589085 0.1889826122612337 0.8501064446343696 1.0 0.9803401617504968 2 Q16836 1
121
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.6103833090732711 0.18034481999311 0.8568818711977961 1.0 0.9803401617504968 2 Q13505 1
122
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.6103833090732711 0.18034481999311 0.8568818711977961 1.0 0.9803401617504968 2 Q13505 1
123
+ Myosin head, motor domain [IPR001609] 0.3223201377179107 0.1754055573679415 0.8607609741364604 1.0 0.9803401617504968 8 Q9UM54,Q9Y4I1 2
124
+ Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186] 0.4256776193930778 0.1752738462685316 0.8608644612941088 1.0 0.9803401617504968 3 P60510 1
125
+ Pre-SET domain [IPR007728] 0.6069868995633229 0.1744476526886923 0.8615136669730179 1.0 0.9803401617504968 2 Q96KQ7 1
126
+ Translation initiation factor IF2/IF5 domain [IPR002735] 0.6035904900533788 0.1686736713651736 0.8660533292247667 1.0 0.9803401617504968 2 P55010 1
127
+ Band 4.1, C-terminal [IPR008379] 0.4103030802731301 0.1457687057994465 0.8841039811325835 1.0 0.9803401617504968 3 Q9Y2J2 1
128
+ FERM adjacent (FA) [IPR014847] 0.4103030802731301 0.1457687057994465 0.8841039811325835 1.0 0.9803401617504968 3 Q9Y2J2 1
129
+ SAB domain [IPR007477] 0.4103030802731301 0.1457687057994465 0.8841039811325835 1.0 0.9803401617504968 3 Q9Y2J2 1
130
+ Arfaptin homology (AH) domain [IPR010504] 0.5875788452207721 0.1431145844781254 0.8861996867628792 1.0 0.9803401617504968 2 P53365 1
131
+ Sorting nexin Vps5-like, C-terminal [IPR015404] 0.5759340126152428 0.1262420667009291 0.8995403133025908 1.0 0.9803401617504968 2 Q9UNH7 1
132
+ Nuclear transport factor 2 domain [IPR002075] 0.5676855895196575 0.1151559991889964 0.9083214741479092 1.0 0.9803401617504968 2 Q9UBU9 1
133
+ Nuclear transport factor 2, eukaryote [IPR018222] 0.5676855895196575 0.1151559991889964 0.9083214741479092 1.0 0.9803401617504968 2 Q9UBU9 1
134
+ ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.341994062716974 0.1048514485609164 0.9164936849572336 1.0 0.9803401617504968 4 P06576 1
135
+ ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.341994062716974 0.1048514485609164 0.9164936849572336 1.0 0.9803401617504968 4 P06576 1
136
+ Ubiquitin-associated domain [IPR015940] 0.2958226794011119 0.1010233344371418 0.919531936732224 1.0 0.9803401617504968 6 Q7Z6Z7 1
137
+ SH3 domain [IPR001452] 0.3589095519084843 0.0994894590129713 0.920749656865946 1.0 0.9803401617504968 21 Q14847,Q99961,P15924,P46109,Q5JRA6,Q9NZW5,Q03001,Q9UPN3 8
138
+ Domain of unknown function DUF1747 [IPR013719] 0.5507035419699258 0.0945465935237167 0.9246749719013668 1.0 0.9803401617504968 2 Q08945 1
139
+ Zinc finger, RING-type [IPR001841] 0.3187120569131972 0.0836667621006694 0.9333213844572932 1.0 0.986969181852954 15 Q9UPN9,O15164,O15344 3
140
+ Zinc finger, PHD-type [IPR001965] 0.3156594821792901 0.0698857979966549 0.944284557046578 1.0 0.994292684849046 16 Q8IWS0,Q9UPN9,O15164 3
141
+ SCP2 sterol-binding domain [IPR003033] 0.3563106796116517 0.0687105314221619 0.945220035155484 1.0 0.994292684849046 3 P22307,Q6YN16 2
142
+ PIK-related kinase [IPR014009] 0.3504854368932067 0.0627525715600293 0.9499635337982631 1.0 0.994292684849046 3 P78527,Q9Y4A5 2
143
+ FATC domain [IPR003152] 0.3504854368932067 0.0627525715600293 0.9499635337982631 1.0 0.994292684849046 3 P78527,Q9Y4A5 2
144
+ PIK-related kinase, FAT [IPR003151] 0.3504854368932067 0.0627525715600293 0.9499635337982631 1.0 0.994292684849046 3 P78527,Q9Y4A5 2
145
+ Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.3504854368932067 0.0627525715600293 0.9499635337982631 1.0 0.994292684849046 3 P78527,Q9Y4A5 2
146
+ Aminotransferase, class I/classII [IPR004839] 0.3064594463331677 0.0576627903620603 0.9540172333447388 1.0 0.994292684849046 4 P17174,Q6YP21,O15269 3
147
+ Dynein heavy chain, tail [IPR013594] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
148
+ Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
149
+ Dynein heavy chain, C-terminal domain [IPR041228] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
150
+ Dynein heavy chain region D6 P-loop domain [IPR004273] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
151
+ Dynein heavy chain, coiled coil stalk [IPR024743] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
152
+ Dynein heavy chain, AAA module D4 [IPR024317] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
153
+ Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
154
+ Dynein heavy chain, linker [IPR013602] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
155
+ Dynein heavy chain AAA lid domain [IPR041658] 0.5094614264920043 0.0561638904199986 0.9552112470065874 1.0 0.994292684849046 2 Q8NCM8 1
156
+ Bromodomain [IPR001487] 0.2688941636277476 0.0349305699607313 0.972135104177726 1.0 1.0 12 Q9UPN9,O15164 2
157
+ Metallo-beta-lactamase [IPR001279] 0.4687045123726413 0.0322286292451508 0.9742897251973224 1.0 1.0 2 Q9BQ52 1
158
+ Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164] 0.4502668607472145 0.0250510214546822 0.9800142671241828 1.0 1.0 2 Q5JTZ9 1
159
+ DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.2901186470774856 0.0231091605194774 0.981563198600646 1.0 1.0 3 P43246 1
160
+ DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.2901186470774856 0.0231091605194774 0.981563198600646 1.0 1.0 3 P43246 1
161
+ DNA mismatch repair protein MutS, connector domain [IPR007860] 0.2901186470774856 0.0231091605194774 0.981563198600646 1.0 1.0 3 P43246 1
162
+ DNA mismatch repair protein MutS, core [IPR007696] 0.2901186470774856 0.0231091605194774 0.981563198600646 1.0 1.0 3 P43246 1
163
+ Band 4.1 domain [IPR019749] 0.2363642867967269 0.0229070064864141 0.9817244514952316 1.0 1.0 8 Q9Y2J2 1
164
+ FERM central domain [IPR019748] 0.2363642867967269 0.0229070064864141 0.9817244514952316 1.0 1.0 8 Q9Y2J2 1
165
+ Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.4313440077632279 0.0195477667664972 0.9844041319414976 1.0 1.0 2 O94776 1
166
+ Syntaxin, N-terminal domain [IPR006011] 0.2786407766990336 0.0192262398291515 0.9846606251128184 1.0 1.0 3 Q12846,O15400 2
167
+ RNA recognition motif domain, eukaryote [IPR003954] 0.2412053550997168 0.0183232412973495 0.9853809867036653 1.0 1.0 10 Q9Y4C8,Q01085,P11940 3
168
+ Dbl homology (DH) domain [IPR000219] 0.41387675885493 0.0158356201271697 0.9873655312430188 1.0 1.0 2 Q14155 1
169
+ Kinesin-like [IPR022164] 0.4133915574963674 0.0157485554486817 0.9874349901440348 1.0 1.0 2 Q12756 1
170
+ ATP:guanido phosphotransferase, N-terminal [IPR022413] 0.4051431344007802 0.0143862889822177 0.9885217980668106 1.0 1.0 2 P12277 1
171
+ ATP:guanido phosphotransferase, catalytic domain [IPR022414] 0.4051431344007802 0.0143862889822177 0.9885217980668106 1.0 1.0 2 P12277 1
172
+ GCF, C-terminal [IPR022783] 0.3871906841339174 0.0120987693644514 0.9903468142258738 1.0 1.0 2 P16383 1
173
+ Zinc finger, PHD-finger [IPR019787] 0.2577946505648644 0.0115274542060226 0.9908026259586538 1.0 1.0 15 Q9UPN9,O15164 2
174
+ Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.3813682678311511 0.01152580280925 0.9908039434951136 1.0 1.0 2 P13798 1
175
+ Protein kinase domain [IPR000719] 0.3503954985083637 0.0114539680030897 0.9908612555946408 1.0 1.0 33 Q99570,P24941,Q13308,P17612,P06493,Q96KB5,P28482,P51812 8
176
+ Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.3779718583212049 0.0112243921252722 0.9910444188670108 1.0 1.0 2 P09874 1
177
+ Ribosomal protein L11, N-terminal [IPR020784] 0.3770014556040775 0.011142461635072 0.9911097858523616 1.0 1.0 2 Q9Y3B7 1
178
+ Ribosomal protein L11, C-terminal [IPR020783] 0.3770014556040775 0.011142461635072 0.9911097858523616 1.0 1.0 2 Q9Y3B7 1
179
+ SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.3556525958272704 0.0097444744589369 0.9922251573193536 1.0 1.0 2 Q08J23 1
180
+ ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650] 0.2896652110625881 0.0082571078421623 0.993411855999029 1.0 1.0 2 Q96I99 1
181
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.2804463852498754 0.0082058157356165 0.993452779792469 1.0 1.0 2 O60506 1
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Mini-chromosome maintenance protein [IPR031327]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: fb1a99089095f9df1c21dccfe997108ee24bed7f2af9b2ed4cd8ee2ed7e4173e
  • Pointer size: 131 Bytes
  • Size of remote file: 140 kB
interpro_family/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:068faca78f6a1f97fdf6f70623022f4c50b09348cd46da4ad147a4efad6c0a84
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+ size 116853
interpro_family/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_50 pval_100 pval_250 pval_500
interpro_family/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 2063,
4
+ "annotations_size": 1662,
5
+ "title": "Average number of proteins per term",
6
+ "value": 1.256317689530686
7
+ }
interpro_family/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C411/C411_val_log2fc"}