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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:33063fefa80d5337b9a8ceecfcc51c0d6ce6c5b0da035d7a2bf3e6a41ed7587d
+size 58351

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 2468,
+    "annotations_size": 52,
+    "title": "Average number of proteins per term",
+    "value": 2.3076923076923075
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C413/C413_val_log2fc"}

interpro_active_site/result.tsv

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+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.964705882352941	1.7484222955378037	0.0803909300076641	0.98719531814025	0.2762202243298093	3	Q9HB40,P10619	2
+ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]	0.7831456535126627	1.5961153281635694	0.1104630470564731	0.9977273754374688	0.3191154692742557	4	P25705	1
+Histidine acid phosphatase active site [IPR033379]	0.9225466342254632	1.1148997982375224	0.2648933631858736	0.9999998877418516	0.5988893428550187	2	Q9NPH0	1
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.5914069952379943	0.3536519170647668	0.7235997612734619	1.0	0.9567375452951876	3	P00390	1

interpro_active_site/selections.json

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+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK4", "CAPN1", "CASP2", "CASP3", "CDC34", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCS1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MDH1", "MDH2", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PREP", "PRKAA2", "PRKACA", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "RNASET2", "ROCK1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "VRK2"], "leading_proteins": ["ACP6", "ATP5A1", "CTSA", "GSR", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:eca5e81f636d6aa1206e011328de66c52c21b55aa74e4df00d8a00080a2b1d48
+size 56876

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	5	6	2.5088682548478696	0.0121118647835629	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	7.712537917689981e-09	1.0	1.0	1.5040937032126972e-08	9.6474859037805e-07

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2468,
+    "annotations_size": 27,
+    "title": "Average number of proteins per term",
+    "value": 4.148148148148148
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C413/C413_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9057676685621424	2.5088682548478696	0.0121118647835629	0.2803691450892229	0.1680032629543322	6	Q9BVA1,Q13885,P68371,P07437,Q9BUF5	5
+Peptidase M16, zinc-binding site [IPR001431]	0.6925200619354892	1.3923289230864375	0.1638228169284949	0.9920190527038948	0.4914684507854849	5	P22695	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "APOBEC3C", "CALM3", "CALU", "CAMK4", "CAPN1", "CDK1", "CDK12", "CDK2", "CDK4", "CDK5", "CDK6", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "IDE", "ILKAP", "IQGAP1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN2", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SPTAN1", "SRI", "SRPK1", "STK26", "TKT", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "UQCRC2"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]", "1": "Proteasome beta-type subunit, conserved site [IPR016050]", "2": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:7c07cdb60a225ddc92980b6128280b6718f27d2bee505bcdf49cbe4011e451c3
+size 64348

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	5	6	2.5088682548478696	0.0121118647835629	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.4467970406321997e-06	1.0	1.0	2.765770662469611e-06	0.0001461959825676
+Intermediate filament protein, conserved site [IPR018039]	4	7	2.018142006649203	0.0435764738996147	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.0569887833052036	1.0	1.0	0.0693365470158766	0.0013613651941044

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2468,
+    "annotations_size": 249,
+    "title": "Average number of proteins per term",
+    "value": 2.5461847389558234
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C413/C413_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.9057676685621424	2.5088682548478696	0.0121118647835629	0.9518900838574916	0.4704942067499918	6	Q9BVA1,Q13885,P68371,P07437,Q9BUF5	5
+Intermediate filament protein, conserved site [IPR018039]	0.7621730534860718	2.018142006649203	0.0435764738996147	0.9999847975936508	0.4704942067499918	7	P02545,Q16352,P08670,P48681	4
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7313843060455997	1.8607428822583392	0.0627804949852395	0.9999999026158508	0.4704942067499918	8	P49721,Q99436,P20618,P28072,P28074	5
+Syntaxin/epimorphin, conserved site [IPR006012]	0.736225481364402	1.7853028800532629	0.0742122019697146	0.99999999541487	0.4704942067499918	6	O43752,Q9P2W9,Q86Y82,Q13190	4
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6863217168362798	1.5610642435055166	0.1185085936232723	0.9999999999999772	0.4980705947577174	6	P33991	1
+Tetraspanin, conserved site [IPR018503]	0.9736415247364144	1.3068252485310807	0.1912720680732416	1.0	0.5879845055584835	2	O60637	1
+ABC transporter-like, conserved site [IPR017871]	0.6110967394226849	1.285408224108433	0.1986496688213872	1.0	0.5888543754348265	9	P33527,O75027	2
+Guanylate kinase, conserved site [IPR020590]	0.8348884381338728	1.2345069113572136	0.2170140729462351	1.0	0.6004056018179171	3	Q9NZW5,Q14168	2
+Haem oxygenase conserved site [IPR018207]	0.9399837793998352	1.1800851279872948	0.2379663589767011	1.0	0.6460795268552815	2	P30519	1
+Thioredoxin, conserved site [IPR017937]	0.5662326642206563	1.0725512663929766	0.2834725002807845	1.0	0.7129762885850035	9	Q9H3N1,Q9H1E5	2
+Phosphofructokinase, conserved site [IPR015912]	0.7712723281047711	0.9846216137511538	0.324809968934904	1.0	0.7505213579159778	3	P17858	1
+Sterol reductase, conserved site [IPR018083]	0.7708964716737601	0.9831627679110392	0.3255273359635566	1.0	0.7505213579159778	3	Q14739	1
+Glycoside hydrolase, family 29, conserved site [IPR018526]	0.823600973236005	0.7571471606557408	0.448961702458547	1.0	0.9020463506354762	2	Q9BTY2	1
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.7725060827250599	0.5864421507239798	0.5575784258011858	1.0	0.9641460279478836	2	P27361	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.452130164490122	0.5543997541404841	0.5793052943176928	1.0	0.9772386134894944	8	P51648	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.7169505271695051	0.4189109593271182	0.6752812073265848	1.0	1.0	2	O00429	1
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.6125760649087131	0.4170222671700632	0.676662120622552	1.0	1.0	3	Q9H3P7,Q5T8D3	2
+Clathrin adaptor complex, small chain [IPR000804]	0.539148073022301	0.2171167633040373	0.8281173503251578	1.0	1.0	3	Q92572,P53680	2
+Aldehyde dehydrogenase, glutamic acid active site [IPR029510]	0.3636307179233726	0.1831681283883186	0.8546661011258934	1.0	1.0	8	P51648	1
+14-3-3 protein, conserved site [IPR023409]	0.3379366368805875	0.0788609468873493	0.937143226328957	1.0	1.0	6	P63104,P31946,P27348,P62258,P61981	5
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.5113544201135389	0.0555208911776015	0.9557234868655532	1.0	1.0	2	Q16836	1
+Profilin conserved site [IPR027310]	0.4521492295214864	0.0261438809506948	0.9791425770738588	1.0	1.0	2	P35080	1
+Actin/actin-like conserved site [IPR020902]	0.3360389610389583	0.0242110203109597	0.9806842877708216	1.0	1.0	4	P61163,P61158,P42025	3
+Ras GTPase-activating protein, conserved site [IPR023152]	0.4067315490673185	0.0164153492890525	0.9869030344375032	1.0	1.0	2	P21359	1
+Ubiquitin interacting motif [IPR003903]	0.3884833738848371	0.014385222131607	0.9885226492023658	1.0	1.0	2	O14964	1
+Ribosomal protein S2, conserved site [IPR018130]	0.3641524736415297	0.0127170549696883	0.9898535316685816	1.0	1.0	2	Q9Y399	1
+Cadherin conserved site [IPR020894]	0.3874239350912673	0.0086540865069123	0.993095124176446	1.0	1.0	3	Q14126,Q14574	2
+Heat shock protein Hsp90, conserved site [IPR019805]	0.3764705882352889	0.0032261771226133	0.9974258875487731	1.0	1.0	3	P07900,P14625	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bax inhibitor 1, conserved site [IPR006213]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR1B", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARHGEF7", "ARIH2", "ATAD1", "ATP5C1", "ATP5O", "ATP7B", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BLM", "BOP1", "BPTF", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD4", "CMPK1", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CSTB", "CSTF1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIS3", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPRS", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FDFT1", "FDPS", "FEN1", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "INTS12", "IQGAP1", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MGST2", "MID1", "MIF", "MPHOSPH8", "MPI", "MPP1", "MPP2", "MPP6", "MRPL3", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NEFM", "NES", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KB", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2E", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RBBP4", "RCL1", "RDH13", "RDX", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLC4A2", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP2", "TBL1XR1", "TBL3", "TCP1", "THOC6", "TK1", "TLN1", "TM7SF2", "TMBIM6", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC5", "UBA1", "UBA2", "UHRF1", "USP10", "USP14", "USP24", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB7", "ABCC1", "ACBD3", "ACBD5", "ACTR1A", "ACTR1B", "ACTR3", "ALDH3A2", "AP2S1", "AP3S1", "DNM1L", "DSC3", "DSG2", "FUCA2", "HADH", "HGS", "HMOX2", "HSP90AA1", "HSP90B1", "INA", "LBR", "LMNA", "MAPK3", "MCM4", "MPP2", "MPP6", "MRPS2", "NES", "NF1", "PFKL", "PFN2", "PSMB1", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "STX12", "STX18", "STX5", "STX6", "TMX1", "TMX4", "TSPAN3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4B", "TUBB6", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "1": "Tubulin/FtsZ, GTPase domain [IPR003008]", "2": "P-type ATPase, haloacid dehalogenase domain [IPR044492]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "1": "Tubulin/FtsZ, GTPase domain [IPR003008]", "2": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "3": "PDZ domain [IPR001478]", "4": "K Homology domain, type 1 [IPR004088]", "5": "14-3-3 domain [IPR023410]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:c47cb779a07667a7dace1cb8ef09c2fbbdc609f69715f5bdd6c6cbcad3848c87
+size 123146

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	5	6	2.5088682548478696	0.0121118647835629	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	9.822353481558534e-07	1.0	1.0	1.8818469985730976e-06	0.0001016217979366
+Tubulin/FtsZ, GTPase domain [IPR003008]	5	6	2.5088682548478696	0.0121118647835629	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.4467970406321997e-06	1.0	1.0	2.765770662469611e-06	0.0001461959825676
+GOLD domain [IPR009038]	2	7	2.450932226773726	0.0142486778549772	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	0.0311737062966536	0.0619434524836269	0.0066572828402184	0.003355333516566	0.0228394808772788
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	6	2.3254012510786986	0.0200505146526808	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0019123837561572	0.0015075035399645	0.0001778916397324	0.00262770885776	0.000160552482799
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	6	7	2.0989192024931533	0.0358240238048703	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.0114139717359059	1.0	0.191600110602388	0.0153906222854723	0.0004973671187583
+Intermediate filament, rod domain [IPR039008]	4	7	2.018142006649203	0.0435764738996147	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.0813655366945302	1.0	1.0	0.0983610682747182	0.0035606647558243
+ABC transporter type 1, transmembrane domain [IPR011527]	2	5	1.9990243614660257	0.0456057180661624	2.3689320388349513	6.349514563106796	0.6640264147492347	0.3307390797434538	1.7803691733569	2.1393617497725477	1.1694677427725269	0.279101120079799	0.0037697619939986	0.0711332726649859	0.1349531130589082	0.0051503840765812	0.0338099842169397

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2468,
+    "annotations_size": 2206,
+    "title": "Average number of proteins per term",
+    "value": 2.048050770625567
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C413/C413_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,165 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.9057676685621424	2.5088682548478696	0.0121118647835629	0.9999999999978848	0.59270955545224	6	Q9BVA1,Q13885,P68371,P07437,Q9BUF5	5
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.9057676685621424	2.5088682548478696	0.0121118647835629	0.9999999999978848	0.59270955545224	6	Q9BVA1,Q13885,P68371,P07437,Q9BUF5	5
+GOLD domain [IPR009038]	0.8629923701805394	2.450932226773726	0.0142486778549772	0.9999999999999822	0.59270955545224	7	Q9Y3B3,Q15363	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.8613928420849606	2.3254012510786986	0.0200505146526808	1.0	0.59270955545224	6	O15173,O43169	2
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7805770012190212	2.0989192024931533	0.0358240238048703	1.0	0.59270955545224	7	P35670,P98194,P05023,P16615,P23634,Q9HD20	6
+Intermediate filament, rod domain [IPR039008]	0.7621730534860718	2.018142006649203	0.0435764738996147	1.0	0.59270955545224	7	P02545,Q16352,P08670,P48681	4
+ABC transporter type 1, transmembrane domain [IPR011527]	0.8329297511760333	1.9990243614660257	0.0456057180661624	1.0	0.59270955545224	5	P33527,O75027	2
+Major facilitator superfamily domain [IPR020846]	0.8200509579470134	1.94470346840895	0.0518106778667606	1.0	0.59270955545224	5	P53985,Q6NT16,Q7L0J3	3
+Peptidase M16, C-terminal [IPR007863]	0.7334227651841688	1.8903637099564752	0.0587093334341399	1.0	0.59270955545224	7	P22695,Q5JRX3	2
+Peptidase M16, N-terminal [IPR011765]	0.7334227651841688	1.8903637099564752	0.0587093334341399	1.0	0.59270955545224	7	P22695,Q5JRX3	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7799431587494858	1.7736678542309343	0.0761181066585003	1.0	0.59270955545224	5	P98194,P16615,P05023,P23634	4
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7799431587494858	1.7736678542309343	0.0761181066585003	1.0	0.59270955545224	5	P98194,P16615,P05023,P23634	4
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.7069938378940381	1.654514723914806	0.098022974184867	1.0	0.6125741672855998	6	O95140,O00429,Q9H4M9,O60313	4
+Dynamin, N-terminal [IPR045063]	0.7069938378940381	1.654514723914806	0.098022974184867	1.0	0.6125741672855998	6	O95140,O00429,Q9H4M9,O60313	4
+ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]	0.7831456535126627	1.5961153281635694	0.1104630470564731	1.0	0.6257267518604803	4	P25705	1
+ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]	0.7831456535126627	1.5961153281635694	0.1104630470564731	1.0	0.6257267518604803	4	P25705	1
+MCM OB domain [IPR033762]	0.6863217168362798	1.5610642435055166	0.1185085936232723	1.0	0.6257267518604803	6	P33991	1
+MCM domain [IPR001208]	0.6863217168362798	1.5610642435055166	0.1185085936232723	1.0	0.6257267518604803	6	P33991	1
+MCM N-terminal domain [IPR027925]	0.6863217168362798	1.5610642435055166	0.1185085936232723	1.0	0.6257267518604803	6	P33991	1
+MCM, AAA-lid domain [IPR041562]	0.6863217168362798	1.5610642435055166	0.1185085936232723	1.0	0.6257267518604803	6	P33991	1
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.7402475169157053	1.414681714271674	0.1571618380952206	1.0	0.672326372574249	4	Q9NZW5,Q14168	2
+Guanylate kinase-like domain [IPR008144]	0.7402475169157053	1.414681714271674	0.1571618380952206	1.0	0.672326372574249	4	Q9NZW5,Q14168	2
+LEM domain [IPR003887]	0.6449205733548123	1.3718111475519177	0.1701222360699839	1.0	0.683738789465237	6	P50402,Q86XL3	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.6873976784103513	1.369702666174285	0.1707797360952108	1.0	0.683738789465237	5	Q9UIQ6	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.6873976784103513	1.369702666174285	0.1707797360952108	1.0	0.683738789465237	5	Q9UIQ6	1
+Zinc finger, CHHC-type [IPR012996]	0.859229208924948	1.3310146834286958	0.183184179523405	1.0	0.6972141793151274	3	P55795,P52597	2
+ABC transporter-like, ATP-binding domain [IPR003439]	0.6110967394226849	1.285408224108433	0.1986496688213872	1.0	0.7034047663242059	9	P33527,O75027	2
+Intermediate filament head, DNA-binding domain [IPR006821]	0.8397565922920855	1.2537887490169637	0.2099187997026728	1.0	0.7080747280490768	3	Q16352,P08670	2
+C2 domain [IPR000008]	0.6185105133715398	1.2499181625347398	0.2113294439391757	1.0	0.7095780111565018	6	Q9BSJ8,Q86YQ8	2
+Reticulon [IPR003388]	0.957015409570153	1.2440947601666674	0.2134646893028933	1.0	0.712696957599466	2	O95197	1
+Rpn11/EIF3F, C-terminal [IPR024969]	0.6923089511269485	1.2106948786734075	0.2260123659139012	1.0	0.7304352623418305	4	Q7L5N1	1
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.8249709048058382	1.1952698334074634	0.2319816219959771	1.0	0.7320529566602012	3	P61289	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.8249709048058382	1.1952698334074634	0.2319816219959771	1.0	0.7320529566602012	3	P61289	1
+ERAP1-like C-terminal domain [IPR024571]	0.8121703853955329	1.144739021842342	0.2523172817595829	1.0	0.7320529566602012	3	P55786,Q9UIQ6	2
+NOPS [IPR012975]	0.8097363083164275	1.135147668719025	0.2563134515751732	1.0	0.735812669166204	3	Q8WXF1,Q15233	2
+Band 7 domain [IPR001107]	0.5636033513809082	1.100502690830791	0.271113157863009	1.0	0.7466612062993732	7	Q99623,Q9UJZ1,P27105	3
+Zinc finger, RanBP2-type [IPR001876]	0.5648608985822872	1.0861776049907146	0.2774004233306411	1.0	0.7563315076306301	8	P35637,Q92804,Q01844	3
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.6494539262245054	1.0286744399508765	0.3036326847547714	1.0	0.7831238114729435	4	P13674	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.6494539262245054	1.0286744399508765	0.3036326847547714	1.0	0.7831238114729435	4	P13674	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.5600269501650651	1.0230575283434271	0.3062806464815533	1.0	0.7831238114729435	10	Q9UHX1	1
+Phosphofructokinase domain [IPR000023]	0.7712723281047711	0.9846216137511538	0.324809968934904	1.0	0.8050907769330317	3	P17858	1
+Peptidase M28 [IPR007484]	0.76174784961356	0.9477434399054616	0.3432600805785579	1.0	0.8184959312675782	3	Q969V3	1
+Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]	0.8771289537712861	0.9475117570970392	0.3433780680973024	1.0	0.8184959312675782	2	P06865	1
+Glycoside hydrolase family 20, catalytic domain [IPR015883]	0.8771289537712861	0.9475117570970392	0.3433780680973024	1.0	0.8184959312675782	2	P06865	1
+FAD-binding domain, PCMH-type [IPR016166]	0.8657745336577415	0.9063854803742613	0.3647318552364662	1.0	0.846055176289847	2	Q15392	1
+FAD linked oxidase, N-terminal [IPR006094]	0.8657745336577415	0.9063854803742613	0.3647318552364662	1.0	0.846055176289847	2	Q15392	1
+Phox homology [IPR001683]	0.6193597478825811	0.9021067397689964	0.3670001689765323	1.0	0.8466289779198418	4	O60749	1
+L27 domain, C-terminal [IPR014775]	0.8592862935928628	0.8830451117159744	0.3772118982616417	1.0	0.849554653450766	2	Q9NZW5	1
+L27 domain [IPR004172]	0.8592862935928628	0.8830451117159744	0.3772118982616417	1.0	0.849554653450766	2	Q9NZW5	1
+FAD/NAD(P)-binding domain [IPR023753]	0.5705688675734422	0.8529912236410028	0.3936641711636479	1.0	0.8701634885641356	5	P00390,O95831	2
+MHC class I-like antigen recognition-like [IPR011161]	0.8459042984590426	0.8353128923932441	0.4035415603311298	1.0	0.876193584734717	2	P04439	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8459042984590426	0.8353128923932441	0.4035415603311298	1.0	0.876193584734717	2	P04439	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8459042984590426	0.8353128923932441	0.4035415603311298	1.0	0.876193584734717	2	P04439	1
+Immunoglobulin C1-set [IPR003597]	0.8459042984590426	0.8353128923932441	0.4035415603311298	1.0	0.876193584734717	2	P04439	1
+Glycosyl transferase, family 1 [IPR001296]	0.837388483373882	0.8052496440566755	0.4206756339176407	1.0	0.8871992814744889	2	Q2TAA5	1
+Dynamin, GTPase domain [IPR001401]	0.7172413793103394	0.7785579135580306	0.4362401790342916	1.0	0.9006057558085186	3	O00429,O60313	2
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.8292781832927791	0.7768643822691337	0.4372387871581702	1.0	0.9006057558085186	2	Q14011	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8240064882400624	0.7585512113529508	0.4481210674144515	1.0	0.9093014715776172	2	Q9NVI7	1
+Alpha-L-fucosidase, C-terminal [IPR031919]	0.823600973236005	0.7571471606557408	0.448961702458547	1.0	0.9093014715776172	2	Q9BTY2	1
+Fatty acid desaturase domain [IPR005804]	0.8191403081913963	0.7417477340809953	0.4582401927679471	1.0	0.9143865741229628	2	O15121	1
+Complex 1 LYR protein domain [IPR008011]	0.8183292781832854	0.738956866574617	0.4599331895765446	1.0	0.915715357586514	2	Q9Y6M9	1
+CARG-binding factor, N-terminal [IPR012956]	0.8130575831305766	0.720885894928604	0.4709797218073843	1.0	0.9203804020051216	2	Q14103	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8126520681265204	0.7195009093044071	0.4718323421636698	1.0	0.9203804020051216	2	Q92945	1
+Immunoglobulin-like domain [IPR007110]	0.4849365434609529	0.7063231300322466	0.4799872125154709	1.0	0.923148902187558	8	P35613,P04439	2
+EF-hand, Ca insensitive [IPR014837]	0.6945233265720019	0.6948646625436727	0.4871401201301659	1.0	0.9280061355847548	3	Q13813,O43707	2
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8045417680454128	0.691959522512014	0.4889627489994308	1.0	0.9290713387534404	2	P13674	1
+Lamin tail domain [IPR001322]	0.6864097363083086	0.665533051477428	0.5057096109082746	1.0	0.9390664601748504	3	P02545,Q03252	2
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.6839756592292014	0.6567970404316691	0.511311427474185	1.0	0.9390664601748504	3	Q96G23,Q15629	2
+Fibronectin type II domain [IPR000562]	0.7935928629359259	0.6552817061700877	0.5122863968796649	1.0	0.9390664601748504	2	Q9UBV2	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.7899432278994298	0.6431917149066797	0.520099708624417	1.0	0.9390664601748504	2	P35611	1
+Post-SET domain [IPR003616]	0.7891321978913151	0.6405146340756861	0.5218380782577909	1.0	0.9390664601748504	2	Q03164	1
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.787915652879151	0.6365056371271158	0.5244469079489644	1.0	0.9390664601748504	2	O60749	1
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.7789943227899404	0.6073556380322466	0.5436149220906312	1.0	0.9460937754200788	2	P23634	1
+SCP2 sterol-binding domain [IPR003033]	0.6539553752535421	0.5517656528782524	0.5811089224315713	1.0	0.9573901430517756	3	Q6YN16,P51659	2
+BRO1 domain [IPR004328]	0.7603406326034002	0.5479214693786539	0.5837458263572315	1.0	0.9573901430517756	2	Q5VW32	1
+Syntaxin, N-terminal domain [IPR006011]	0.6449094262832511	0.5212190741396282	0.6022141681398967	1.0	0.969716069439148	3	Q86Y82	1
+Sec23, C-terminal [IPR037550]	0.740875912408756	0.4883264425158674	0.6253186346639805	1.0	0.982137058367908	2	Q15436	1
+MIRO domain [IPR020860]	0.7396593673965934	0.4846907599459686	0.6278957219130055	1.0	0.9830475096075172	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.7396593673965934	0.4846907599459686	0.6278957219130055	1.0	0.9830475096075172	2	Q8IXI1	1
+EF hand associated, type-2 [IPR013567]	0.7396593673965934	0.4846907599459686	0.6278957219130055	1.0	0.9830475096075172	2	Q8IXI1	1
+Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]	0.7311435523114285	0.4595510460765343	0.6458385041760502	1.0	0.9873123405629542	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, central domain [IPR012000]	0.7311435523114285	0.4595510460765343	0.6458385041760502	1.0	0.9873123405629542	2	A1L0T0	1
+Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]	0.7311435523114285	0.4595510460765343	0.6458385041760502	1.0	0.9873123405629542	2	A1L0T0	1
+LEM-like domain [IPR013146]	0.7234387672343854	0.4372883245637051	0.6619022615602554	1.0	0.9873123405629542	2	P42167	1
+Cyclic nucleotide-binding domain [IPR000595]	0.6178307824468569	0.4333803073024665	0.6647385045894418	1.0	0.9873123405629542	3	P10644	1
+SUN coiled coil domain 2 [IPR040994]	0.7210056772100495	0.4303564602027114	0.6669363622203441	1.0	0.9873123405629542	2	Q9UH99	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.720194647201946	0.4280565408330652	0.6686099562427061	1.0	0.9873123405629542	2	O43390	1
+Dynamin GTPase effector [IPR003130]	0.7169505271695051	0.4189109593271182	0.6752812073265848	1.0	0.9873123405629542	2	O00429	1
+Dynamin stalk domain [IPR000375]	0.7169505271695051	0.4189109593271182	0.6752812073265848	1.0	0.9873123405629542	2	O00429	1
+GTPase effector domain [IPR020850]	0.7169505271695051	0.4189109593271182	0.6752812073265848	1.0	0.9873123405629542	2	O00429	1
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.6125760649087131	0.4170222671700632	0.676662120622552	1.0	0.9873123405629542	3	Q9H3P7,Q5T8D3	2
+DNA mismatch repair protein MutS, clamp [IPR007861]	0.7064071370640668	0.3898000067832887	0.6966844387522653	1.0	0.9873123405629542	2	P43246	1
+STAT transcription factor, protein interaction [IPR013799]	0.7011354420113507	0.3756062993313013	0.7072096069488487	1.0	0.9873123405629542	2	P42224	1
+STAT transcription factor, DNA-binding [IPR013801]	0.7011354420113507	0.3756062993313013	0.7072096069488487	1.0	0.9873123405629542	2	P42224	1
+STAT transcription factor, all-alpha domain [IPR013800]	0.7011354420113507	0.3756062993313013	0.7072096069488487	1.0	0.9873123405629542	2	P42224	1
+Chromo shadow domain [IPR008251]	0.5955375253549602	0.3656846959209142	0.7146003672280588	1.0	0.9873123405629542	3	P83916,Q13185	2
+Chromo domain subgroup [IPR017984]	0.5955375253549602	0.3656846959209142	0.7146003672280588	1.0	0.9873123405629542	3	P83916,Q13185	2
+Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]	0.5914069952379943	0.3536519170647668	0.7235997612734619	1.0	0.9873123405629542	3	P00390	1
+Serine-tRNA ligase catalytic core domain [IPR033729]	0.6905920519059208	0.3479711752694002	0.7278618311114289	1.0	0.9873123405629542	2	P49591	1
+Tudor domain [IPR002999]	0.4152605419126821	0.3411646478865756	0.7329796353342539	1.0	0.9873123405629542	6	Q14739	1
+PDZ domain [IPR001478]	0.4155823229937059	0.3265778405184209	0.7439872060334916	1.0	0.9873123405629542	12	Q96RT1,Q9HD26,Q14160,Q9NZW5,Q00013,Q14168	6
+Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]	0.5784963829658853	0.3171447580555305	0.7511337644281704	1.0	0.9873123405629542	3	Q13464	1
+Tim44-like domain [IPR007379]	0.6759935117599314	0.3114326999896279	0.7554716980474887	1.0	0.9873123405629542	2	O43615	1
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.672343876723438	0.3026225280576644	0.7621775441295897	1.0	0.9873123405629542	2	Q5BKZ1	1
+Myosin tail [IPR002928]	0.5679513184584074	0.288623682069723	0.7728693707498806	1.0	0.9873123405629542	3	P35579,P35580	2
+AGC-kinase, C-terminal [IPR000961]	0.4540143672626128	0.2810892648579227	0.7786419347754898	1.0	0.9873123405629542	4	P51812	1
+Zinc finger, C3HC4 RING-type [IPR018957]	0.6565287915652872	0.2660013839801106	0.7902381431498773	1.0	0.9873123405629542	2	O75150	1
+Methyltransferase type 11 [IPR013216]	0.6496350364963486	0.2508496698574328	0.8019303380085909	1.0	0.9873123405629542	2	Q8N6R0	1
+Kinesin-like [IPR022164]	0.6480129764801279	0.2473576225527793	0.8046314675710033	1.0	0.9873123405629542	2	Q9Y3P9	1
+Ras GTPase-activating domain [IPR001936]	0.551255036271888	0.2459937576677009	0.8056870647182774	1.0	0.9873123405629542	3	Q14C86	1
+Ribosome receptor lysine/proline rich [IPR007794]	0.6155717761557145	0.1835122268494145	0.8543961260420285	1.0	0.9873123405629542	2	Q9P2E9	1
+FATC domain [IPR003152]	0.51845841784989	0.1719252535138593	0.8634962927547774	1.0	0.9873123405629542	3	P78527,P42345	2
+PIK-related kinase [IPR014009]	0.51845841784989	0.1719252535138593	0.8634962927547774	1.0	0.9873123405629542	3	P78527,P42345	2
+PIK-related kinase, FAT [IPR003151]	0.51845841784989	0.1719252535138593	0.8634962927547774	1.0	0.9873123405629542	3	P78527,P42345	2
+Exportin-2, central domain [IPR013713]	0.5135902636916713	0.1620752387638628	0.8712466049749623	1.0	0.9873123405629542	3	O15397,P55060	2
+K Homology domain, type 1 [IPR004088]	0.3964402558617464	0.1386251241830276	0.8897463887688355	1.0	0.9873123405629542	20	Q92945,P61978,Q9NQT5,Q96AE4,Q9Y6M1,Q96PU8,Q96I24,Q07666,P51116	9
+Aldehyde dehydrogenase domain [IPR015590]	0.356997674621847	0.1321330532203914	0.8948790524214747	1.0	0.9873123405629542	10	P51648	1
+CBS domain [IPR000644]	0.4880324543610481	0.115362929037027	0.9081574610793504	1.0	0.9922711040817468	3	P54619,P51798	2
+U-box domain [IPR003613]	0.3892045454545425	0.1132662632824606	0.9098194630799364	1.0	0.9929403722533952	4	Q9UMS4,Q7Z6E9,P19474	3
+Ku70/Ku80, N-terminal alpha/beta [IPR005161]	0.5575831305758265	0.0983629059809678	0.9216441285400894	1.0	0.9958415354447288	2	P13010	1
+Ku70/Ku80 beta-barrel domain [IPR006164]	0.5575831305758265	0.0983629059809678	0.9216441285400894	1.0	0.9958415354447288	2	P13010	1
+Ku70/Ku80 C-terminal arm [IPR005160]	0.5575831305758265	0.0983629059809678	0.9216441285400894	1.0	0.9958415354447288	2	P13010	1
+G-protein gamma-like domain [IPR015898]	0.5462287104622886	0.0859190826327574	0.9315307418570158	1.0	0.9958415354447288	2	P63218	1
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.5409570154095694	0.0805843368700253	0.9357725230562828	1.0	0.9958415354447288	2	Q6P1M0	1
+rRNA-processing arch domain [IPR025696]	0.5401459854014531	0.0797879988263264	0.9364058694412094	1.0	0.9958415354447288	2	Q15477	1
+ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]	0.5401459854014531	0.0797879988263264	0.9364058694412094	1.0	0.9958415354447288	2	Q15477	1
+14-3-3 domain [IPR023410]	0.3379366368805875	0.0788609468873493	0.937143226328957	1.0	0.9958415354447288	6	P63104,P31946,P27348,P62258,P61981	5
+Peptidase M41 [IPR000642]	0.5263584752635835	0.0672181948359739	0.9464080004984894	1.0	0.997409730974761	2	Q9Y4W6	1
+Dbl homology (DH) domain [IPR000219]	0.525141930251412	0.0661947833498509	0.947222749951099	1.0	0.997409730974761	2	Q14155	1
+PurM-like, C-terminal domain [IPR010918]	0.4503042596348797	0.0616914512875567	0.9508085478877047	1.0	0.9997538878171006	3	O15067,P49903	2
+FDF domain [IPR019050]	0.5158150851581448	0.0587918218745653	0.9531179223934044	1.0	1.0	2	Q96F86	1
+DFDF domain [IPR025762]	0.5158150851581448	0.0587918218745653	0.9531179223934044	1.0	1.0	2	Q96F86	1
+Lsm14-like, N-terminal [IPR025609]	0.5158150851581448	0.0587918218745653	0.9531179223934044	1.0	1.0	2	Q96F86	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.5113544201135389	0.0555208911776015	0.9557234868655532	1.0	1.0	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.5113544201135389	0.0555208911776015	0.9557234868655532	1.0	1.0	2	Q16836	1
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.5052716950527126	0.0513308349249977	0.9590618977670812	1.0	1.0	2	Q96EY1	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.4389452332657075	0.0489626505092149	0.9609490607963008	1.0	1.0	3	Q96EY1,P31689	2
+Acyltransferase, C-terminal domain [IPR032098]	0.4975669099756717	0.0464539679822547	0.9629484226770446	1.0	1.0	2	Q92604	1
+DNA mismatch repair protein MutS, core [IPR007696]	0.4355734957018201	0.0454737790011221	0.9637296745977408	1.0	1.0	3	P43246	1
+DNA mismatch repair protein MutS, connector domain [IPR007860]	0.4355734957018201	0.0454737790011221	0.9637296745977408	1.0	1.0	3	P43246	1
+DNA mismatch repair protein MutS-like, N-terminal [IPR007695]	0.4355734957018201	0.0454737790011221	0.9637296745977408	1.0	1.0	3	P43246	1
+DNA mismatch repair protein MutS, C-terminal [IPR000432]	0.4355734957018201	0.0454737790011221	0.9637296745977408	1.0	1.0	3	P43246	1
+Heat shock chaperonin-binding [IPR006636]	0.4955393349553846	0.0452477194890693	0.9639098585234548	1.0	1.0	2	P54727	1
+Man1/Src1, C-terminal [IPR018996]	0.4886455798864547	0.0413773723073244	0.9669950516281828	1.0	1.0	2	Q8NC56	1
+Peptidase M16, middle/third domain [IPR032632]	0.4858069748580693	0.0398843486482623	0.968185329143766	1.0	1.0	2	O43847	1
+PABP, RNA recognition motif 2 [IPR045305]	0.4789132197891262	0.0364922089690408	0.9708898909154178	1.0	1.0	2	Q13310	1
+TOG domain [IPR034085]	0.3213149026014023	0.035698337848471	0.9715228959136144	1.0	1.0	6	Q8TEX9,O00410	2
+BAR domain [IPR004148]	0.4162271805273688	0.0278884954878832	0.9777510841467096	1.0	1.0	3	Q9Y371,Q68EM7	2
+CRAL-TRIO lipid binding domain [IPR001251]	0.4537712895377173	0.0266559374147155	0.9787341574812998	1.0	1.0	2	P21359	1
+Gelsolin-like domain [IPR007123]	0.3378392697059809	0.0265024919983417	0.9788565459712352	1.0	1.0	4	Q15437,Q15436	2
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.4525547445255422	0.0262706268105201	0.9790414832318322	1.0	1.0	2	Q15008	1
+PurM-like, N-terminal domain [IPR016188]	0.4501216545012134	0.0255226647469144	0.9796380705204693	1.0	1.0	2	P49903	1
+Jumonji, helical domain [IPR041070]	0.4432278994322795	0.0235611701646238	0.9812026452659262	1.0	1.0	2	O75151	1
+Ras-associating (RA) domain [IPR000159]	0.4355231143552322	0.0216272109405084	0.98274532741381	1.0	1.0	2	Q9Y4G8	1
+ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]	0.4351175993511678	0.021532529857405	0.982820854400031	1.0	1.0	2	Q14240	1
+Histone deacetylase domain [IPR023801]	0.4294403892943925	0.0202774032902379	0.9838220816432404	1.0	1.0	2	Q13547	1
+Cadherin prodomain [IPR014868]	0.3872668288726697	0.0142768797566297	0.9886090850340896	1.0	1.0	2	Q14574	1
+Cadherin, cytoplasmic domain [IPR000233]	0.3872668288726697	0.0142768797566297	0.9886090850340896	1.0	1.0	2	Q14574	1
+Staufen, C-terminal [IPR032478]	0.3860502838605026	0.0141715255847355	0.9886931369977608	1.0	1.0	2	O75569	1
+IBR domain [IPR002867]	0.3746958637469629	0.0133209335248752	0.989371747131693	1.0	1.0	2	Q9Y4X5	1
+Ariadne domain [IPR045840]	0.3746958637469629	0.0133209335248752	0.989371747131693	1.0	1.0	2	Q9Y4X5	1
+TRIAD supradomain [IPR044066]	0.3746958637469629	0.0133209335248752	0.989371747131693	1.0	1.0	2	Q9Y4X5	1
+Cadherin-like [IPR002126]	0.3874239350912673	0.0086540865069123	0.993095124176446	1.0	1.0	3	Q14126,Q14574	2
+Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]	0.3157467532467501	0.0016509366418597	0.9986827437409802	1.0	1.0	4	Q6PI48,Q15046,O43776	3

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin [IPR002453]", "1": "Tubulin [IPR000217]", "2": "Proteasome B-type subunit [IPR023333]", "3": "P-type ATPase [IPR001757]"}