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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Response of eif2ak4 gcn2 to amino acid deficiency 0.4769576719010811 2.904509035969584 0.0036782958582373 0.9925619976904764 0.5574231731880368 73 P83881,P27635,P61313,P18621,P08708,P62910,P62266,P42766,P40429,P08243,P18077,Q02878,P60866,Q9Y3U8,P39023,Q92616,P62917,Q07020,Q02543,P36578,P62899 21
Eukaryotic translation elongation 0.4713927213408722 2.81893519600303 0.0048183244797415 0.998377618483836 0.5574231731880368 74 P83881,P27635,Q05639,P61313,P13639,P18621,P08708,P62910,P62266,P42766,P40429,P18077,Q02878,P60866,Q9Y3U8,P39023,P62917,Q07020,Q02543,P36578,P62899 21
Defects in biotin btn metabolism 0.881350180327071 2.7861466905135033 0.0053338728182839 0.9991855827871882 0.5574231731880368 7 Q13085,Q96RQ3,P11498,P50747 4
Selenoamino acid metabolism 0.4826873499090301 2.718048970530637 0.0065668118153767 0.999843532570222 0.5574231731880368 85 P83881,P27635,P07814,P14868,P61313,P18621,P08708,P62910,P62266,P42766,Q16881,P40429,P18077,P49591,Q02878,P60866,Q9P2J5,Q9Y3U8,Q15046,P39023,P62917,Q07020,Q02543,P36578,P62899 25
Biotin transport and metabolism 0.8335862726102524 2.683507160637505 0.0072854415039116 0.9999402359482668 0.5574231731880368 9 Q96RQ3,P50747,Q13085,P11498,P05165 5
Defects in vitamin and cofactor metabolism 0.8195202692695005 2.618625408256843 0.008828483404361 0.9999924504419572 0.5574231731880368 9 Q13085,Q96RQ3,P11498,P50747 4
Nonsense mediated decay nmd 0.4590873523465023 2.5272338483565453 0.0114964924980072 0.999999790576461 0.5574231731880368 81 P83881,P27635,P61313,P18621,P08708,P62910,P62266,P42766,P40429,P18077,Q02878,P60866,Q9Y3U8,Q9BZI7,P15170,P39023,P62917,Q07020,Q9NPI6,Q02543,P36578,P62899,Q04637 23
Metabolism of water soluble vitamins and cofactors 0.5944554005327984 2.4939771268940985 0.0126320684259821 0.9999999545960472 0.5574231731880368 28 Q96RQ3,Q9H2D1,P11586,P50747,Q13085,P11498,P05165,O00763,P49327 9
Parasite infection 0.60245345984031 2.470719912930318 0.0134841382992205 0.9999999855982138 0.5574231731880368 19 Q7L576,O15143,Q14185,Q9UQB8,P61160,P35579,Q9Y2A7 7
Protein ubiquitination 0.5920491458475774 2.4379247728521705 0.0147718477331799 0.999999997465097 0.5574231731880368 25 P49427,A0AVT1,P78527,Q5VTR2,Q92541,Q93008,Q14527 7
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.7900603941638591 2.37690685477031 0.0174584960993069 0.999999999932903 0.5574231731880368 7 P09874,Q93008,Q9UPN9 3
Nuclear events stimulated by alk signaling in cancer 0.6890933725635261 2.272415102285271 0.0230614504031212 0.9999999999999666 0.5574231731880368 12 P33176,P40763,Q00610,Q9HC35,Q86WB0 5
Downregulation of smad2 3 smad4 transcriptional activity 0.8703978051428984 2.255012993856622 0.0241325131908582 0.9999999999999922 0.5574231731880368 5 P09874,Q93008,Q9UPN9 3
Signaling by alk in cancer 0.5562409063325754 2.2470277142908026 0.02463825597443 0.999999999999996 0.5574231731880368 30 Q9P2E9,P10644,P33176,P40763,Q9NR09,P12270,Q00610,Q9HC35,P35579,Q14203,P18206,Q86WB0 12
Cytosolic trna aminoacylation 0.5658887461278312 2.238180357146339 0.0252092960681364 0.9999999999999982 0.5574231731880368 23 P23381,P26640,O43776,P07814,P49588,P26639,P54136,Q15046,P49591,P14868,Q9NSD9,Q9P2J5 12
Cellular response to starvation 0.4298824599274153 2.1824150957353443 0.0290789112108829 1.0 0.5574231731880368 81 P83881,P27635,P61313,P18621,P08708,P38606,P62910,P62266,P42766,P40429,P08243,P18077,Q02878,P60866,Q9Y3U8,P39023,Q92616,P62917,Q07020,Q02543,P36578,P62899 22
Signaling by tgfb family members 0.5744620550896467 2.1517031381030485 0.0314207428330117 1.0 0.5574231731880368 17 Q7Z3T8,P09874,P22681,Q9UPN9,Q93008 5
Rho gtpases activate wasps and waves 0.5897422522027617 2.1404859171191504 0.0323155177118268 1.0 0.5574231731880368 15 Q7L576,O15143,Q9UQB8,P61160,Q9Y2A7 5
Fcgamma receptor fcgr dependent phagocytosis 0.54937245876168 2.127881714426459 0.0333468920306199 1.0 0.5574231731880368 24 Q7L576,O15143,Q14185,Q9UQB8,P61160,P28482,P35579,P07900,Q9Y2A7 9
E3 ubiquitin ligases ubiquitinate target proteins 0.5781912255331603 2.1192268699090415 0.0340712985225684 1.0 0.5574231731880368 16 Q5VTR2,Q92541,P78527,Q14527 4
Unwinding of dna 0.7258546490701194 2.0770799293313664 0.037794182685592 1.0 0.5574231731880368 7 P49736,P25205,P33991,P33993 4
Tp53 regulates transcription of dna repair genes 0.539779773757469 2.045873575424657 0.0407688107835144 1.0 0.5574231731880368 20 Q9NYV4,P19447,P24928,Q08945,Q9Y5B9,Q14676,Q9NVI1 7
Trna aminoacylation 0.5170744347599563 2.0434433961408045 0.0410085653070391 1.0 0.5574231731880368 35 P23381,P26640,O43776,P07814,P49588,P26639,Q9HA77,Q15046,P49591,P14868,Q9NSD9,Q9P2J5,Q9BW92,Q5JPH6,Q9NP81 15
Dna strand elongation 0.5367016763857478 2.02462217274139 0.0429061756975264 1.0 0.5574231731880368 19 P33992,P12004,P25205,P28340,P35251,Q9Y2S7,P39748,P33993,P33991,P49736 10
Metabolism of vitamins and cofactors 0.5100942539633921 2.01096966147543 0.0443286613485973 1.0 0.5574231731880368 36 Q96RQ3,Q9H2D1,P11586,Q9NVE7,P50747,Q13085,P11498,P05165,O00763,P29375,P49327 11
Mecp2 regulates neuronal receptors and channels 0.7068362704844643 1.9863952092567627 0.0469894581726113 1.0 0.5604778201343309 7 Q13547,Q92769,Q9NWH9 3
Cell surface interactions at the vascular wall 0.6359829396097344 1.9852047273550677 0.0471216985791353 1.0 0.5604778201343309 12 P53985,P14174 2
Visual phototransduction 0.8043793985363635 1.9790172796475376 0.0478140608003292 1.0 0.5604778201343309 5 P50579 1
Sensory perception 0.5298777850385437 1.9775678580706852 0.0479774782555324 1.0 0.5604778201343309 21 P50579,P35579 2
Metabolism of folate and pterines 0.7737383091110703 1.964239072544063 0.0495023736071607 1.0 0.5604778201343309 6 Q9H2D1 1
Processive synthesis on the c strand of the telomere 0.6912334986906455 1.9561757213661857 0.0504444575256437 1.0 0.5620339246372487 8 P54132,P12004,Q9Y2S7,P39748,Q15554 5
Transcriptional regulation by mecp2 0.6280578069796962 1.9416549190473944 0.0521788896130168 1.0 0.5659094274865353 12 Q96ST3,Q13547,Q92769,Q9NWH9,Q9BZK7,Q9HCE1,Q16566 7
Signaling by alk 0.8549959382615752 1.93686800442204 0.0527614804573912 1.0 0.5659094274865353 4 Q13547,Q92769,P40763 3
Stat3 nuclear events downstream of alk signaling 0.8549959382615752 1.93686800442204 0.0527614804573912 1.0 0.5659094274865353 4 Q13547,Q92769,P40763 3
Cohesin loading onto chromatin 0.6856979373346003 1.929075179459546 0.0537215298141102 1.0 0.5715970772221333 8 Q9Y6X3,Q14683,Q29RF7,Q9NTI5,Q9UQE7 5
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.6737936244810745 1.9168158104120436 0.0552613356337814 1.0 0.5821935754596425 9 Q8IZH2,Q9NPI6,Q9Y2L1 3
Eukaryotic translation initiation 0.4342126187373675 1.9142131957010953 0.0555929203634395 1.0 0.5821935754596425 97 P83881,P27635,P49770,Q13144,P61313,P18621,P08708,P62910,P62266,P42766,O75821,P18077,Q02878,P60866,Q9Y3U8,O60841,P62917,Q07020,Q02543,P36578,P62899,Q14152,Q04637 23
Mitotic telophase cytokinesis 0.6616604785471475 1.904157822150178 0.0568896329861243 1.0 0.5911188427464485 10 Q9Y6X3,Q14683,Q29RF7,Q9NTI5,Q9UQE7 5
Regulation of mecp2 expression and activity 0.6690016848885108 1.8928444967078255 0.0583785521797972 1.0 0.5977201620237783 9 Q96ST3,Q13547,Q92769,Q9BZK7,Q16566 5
Hdms demethylate histones 0.6862695449674915 1.8874040894509 0.0591059955095625 1.0 0.5977201620237783 7 Q7LBC6,O75151 2
Signaling by tgf beta receptor complex 0.5392401020016507 1.8675460604504883 0.0618253708863725 1.0 0.6090756089151828 16 P09874,Q93008,P22681,Q9UPN9 4
Alk mutants bind tkis 0.7705821109961177 1.8347655670638727 0.0665404325501555 1.0 0.6366818366309844 5 P10644,Q00610,Q9NR09 3
Negative regulation of met activity 0.7385468816749782 1.8098448955307769 0.070319843491762 1.0 0.6633006513761949 6 P22681,Q9NWH9 2
Inlb mediated entry of listeria monocytogenes into host cell 0.7615002464988868 1.7956846527925856 0.072544684063587 1.0 0.6683908560055953 5 P22681,Q9NWH9 2
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.6394716267505413 1.790508330129201 0.0733722293058773 1.0 0.6683908560055953 10 P49427,Q93008,A0AVT1,P22314 4
Signaling by ptk6 0.6187020702964783 1.77991997981594 0.0750890573771085 1.0 0.6702580321884888 11 Q14185,P22681,P40763,P11802 4
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.6374153062703913 1.779919977590188 0.0750890577414171 1.0 0.6702580321884888 10 Q8IZH2,Q9NPI6,Q9Y2L1 3
Processive synthesis on the lagging strand 0.6576768230294555 1.748271398311449 0.0804170434257636 1.0 0.6900301145565523 7 P28340,P39748,P12004,Q9Y2S7 4
Pregnenolone biosynthesis 0.8045766992846366 1.7320620995843043 0.083262506341879 1.0 0.6979875154217182 4 O95772 1
Loss of function of mecp2 in rett syndrome 0.7164031832836373 1.711609373967831 0.0869686796617426 1.0 0.7006197006453322 6 Q96ST3,Q13547,Q16566 3
Regulation of tp53 activity through acetylation 0.6489189728629113 1.705326212273376 0.0881336015219429 1.0 0.7006197006453322 7 Q13547,Q92769,Q14839 3
Regulation of tp53 activity through phosphorylation 0.4912384597456916 1.7041805730570552 0.0883473574229403 1.0 0.7006197006453322 23 P54132,Q92547,O60934,P19784,Q08945,Q92804,Q9Y5B9 7
Raf independent mapk1 3 activation 0.7085977258972775 1.6767977827566989 0.09358203147463 1.0 0.7104653024128308 6 P28482,P36507 2
Uptake and function of diphtheria toxin 0.7904142973192481 1.673947189934913 0.0941409786858569 1.0 0.7104653024128308 4 P07900,P13639,Q16881 3
Establishment of sister chromatid cohesion 0.7049055403689269 1.6602992854298215 0.0968542594189496 1.0 0.7104653024128308 6 Q9NTI5,Q29RF7,Q14683 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7272130298471784 1.6470280285840455 0.0995522848635612 1.0 0.7104653024128308 5 P46939,P51532 2
Chrebp activates metabolic gene expression 0.7267035859709844 1.644806889499498 0.1000096409646502 1.0 0.7104653024128308 5 Q13085,O00763,P49327 3
Hur elavl1 binds and stabilizes mrna 0.7266419201812316 1.6445380080306082 0.1000651200199214 1.0 0.7104653024128308 5 Q01105,O14980,P35658 3
Rhou gtpase cycle 0.5531379301922689 1.6343155036214505 0.1021926199670144 1.0 0.7104653024128308 13 Q93008,Q9UM54,O14964,Q00610 4
Prolonged erk activation events 0.6969948956286831 1.6248846287916487 0.1041871440323671 1.0 0.7104653024128308 6 P36507,P46109 2
Negative regulation of fgfr1 signaling 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Negative regulation of fgfr2 signaling 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Signaling by fgfr4 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Negative regulation of fgfr4 signaling 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Spry regulation of fgf signaling 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Signaling by fgfr1 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Signaling by fgfr3 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Negative regulation of fgfr3 signaling 0.6927769290717296 1.6059659299280429 0.1082813959765718 1.0 0.7104653024128308 6 P28482,P22681 2
Interleukin 6 signaling 0.7707936470275385 1.5930657596032638 0.1111454396535716 1.0 0.7104653024128308 4 P22681,P40763 2
Interleukin 6 family signaling 0.7707936470275385 1.5930657596032638 0.1111454396535716 1.0 0.7104653024128308 4 P22681,P40763 2
Mitochondrial trna aminoacylation 0.49524955228338 1.5775203481232445 0.1146758438348933 1.0 0.7104653024128308 16 Q9HA77,Q5JPH6 2
Listeria monocytogenes entry into host cells 0.6226879426659391 1.5758685988133148 0.1150560890235952 1.0 0.7104653024128308 7 P22681,Q9NWH9 2
G0 and early g1 0.6858069217128648 1.574651838307189 0.1153368303345989 1.0 0.7104653024128308 6 P24941,Q13547 2
Telomere c strand lagging strand synthesis 0.5002768816764283 1.5688427013280049 0.1166845957780799 1.0 0.7104653024128308 15 P54132,P12004,P28340,P35251,P49643,Q9Y2S7,P39748,Q15554 8
Formation of rna pol ii elongation complex 0.4698786851421693 1.5478244509430403 0.1216645679247743 1.0 0.7223833720533475 22 P19447,Q6PD62,P24928,Q08945,Q92541,Q7KZ85,Q9Y5B9 7
Rna polymerase i transcription initiation 0.4743810383531145 1.5314627573811637 0.1256550640465876 1.0 0.7427610452531627 18 O94776,O95602,Q3B726,P17480,Q13547,P19447,Q92769,Q14839,Q13330 9
Srp dependent cotranslational protein targeting to membrane 0.3874006826097185 1.5285790653475215 0.1263688290816444 1.0 0.7436749676043679 88 P83881,P27635,O76094,P51571,P61011,P61313,P18621,P08708,P62910,P62266,P42766,P62241,P40429,P18077,Q02878,P09132,P60866,Q9Y3U8,P39023,P62917,Q07020,Q02543,P36578,P62701,P62899 25
Golgi cisternae pericentriolar stack reorganization 0.5957854901706736 1.5206248833247722 0.1283539987379134 1.0 0.7487316593044949 9 Q9H8Y8,P62820 2
Hdr through mmej alt nhej 0.6723486601951741 1.5140177488560929 0.1300213379560224 1.0 0.7551457619279907 6 O60934,P09874 2
Regulation of tp53 activity 0.4440560450368501 1.488333849540379 0.1366628723465885 1.0 0.780092790647909 37 P54132,O60934,Q93009,O94776,Q92547,O60921,Q13547,Q92769,O14744,P19784,Q08945,Q14839,P24941,Q92804,Q9Y5B9 15
Folding of actin by cct tric 0.5964198535394655 1.4833095803629424 0.1379921781309434 1.0 0.7843145167271572 8 P40227,Q99832,P48643,P49368,P17987,P50991,P78371 7
Activation of atr in response to replication stress 0.4717655418130076 1.464404062583526 0.1430835787575437 1.0 0.8063608463878523 17 P33992,P25205,P33993,P33991,Q13416,P49736 6
Activation of the pre replicative complex 0.4770220494971521 1.4560564520164594 0.1453770146227309 1.0 0.8158288162372662 16 Q07864,P33992,P25205,P33993,Q13416,P33991,P49736 7
Dual incision in gg ner 0.4761342936218187 1.4501283143918184 0.1470227406512356 1.0 0.8181600211972528 16 Q07864,P12004,P28340,P35251,P19447,Q9Y2S7,P09874,Q13620 8
Recycling of eif2 gdp 0.5962061718417138 1.4440969293748391 0.1487117117186165 1.0 0.8215202308075433 7 P49770 1
Resolution of abasic sites ap sites 0.4687107023707557 1.4435630088793177 0.1488619365598631 1.0 0.8215202308075433 17 Q07864,P12004,P29372,Q96T60,P28340,P35251,Q9Y2S7,P09874,P39748 9
Dna repair 0.3691279132322493 1.4278391595382678 0.153338158635953 1.0 0.8375131279623174 82 Q07864,P20585,P54132,P19447,P78527,P24928,P09874,P39748,P24941,Q9NVI1,O60934,Q92547,Q93009,P12004,Q14676,Q9UNS2,P13010,P29372,P28340,P35251,Q8TAT6,Q15554,Q9BT78,P30876,O60921,P52701,P18074,Q96T60,Q9Y2S7,P54727,Q13620,Q9HCS7,P61201 33
Nucleotide biosynthesis 0.5343038530529243 1.4152439792653366 0.1569969739142291 1.0 0.8453683210766186 12 P31939,P49915,P22102,P27708,P30520 5
Sting mediated induction of host immune responses 0.6496584528257173 1.4113557567009989 0.1581397416359951 1.0 0.8480881305478769 6 P78527,P13010 2
Dna damage recognition in gg ner 0.4956335086138678 1.406899501198606 0.1594571915246079 1.0 0.8515227483881513 14 Q9UNS2,P09874,P54727,Q9BT78,P61201 5
Foxo mediated transcription 0.5809728598324403 1.4048675519829554 0.160060666990254 1.0 0.8515227483881513 8 Q13547,Q92769 2
Signaling by met 0.4723378872721477 1.386224170662544 0.1656784631142391 1.0 0.8709579286242612 15 O14964,P40763,Q9NWH9,P46109,P22681 5
Insulin receptor signalling cascade 0.6654567897407848 1.3756998034136323 0.1689145928427111 1.0 0.8774616794103494 5 P28482,Q06124,Q99570 3
Constitutive signaling by egfrviii 0.7173055629952358 1.370894329296988 0.170407899348381 1.0 0.8774616794103494 4 P22681 1
Constitutive signaling by ligand responsive egfr cancer variants 0.7173055629952356 1.3708943292969873 0.1704078993483813 1.0 0.8774616794103494 4 P22681 1
Signaling by egfr in cancer 0.7173055629952356 1.3708943292969873 0.1704078993483813 1.0 0.8774616794103494 4 P22681 1
Atf4 activates genes in response to endoplasmic reticulum stress 0.5661118002711931 1.3672917960716782 0.171533862140369 1.0 0.8774616794103494 9 Q9Y2L1,P08243 2
Uptake and actions of bacterial toxins 0.5629878991224456 1.3132647980305991 0.1890937359834992 1.0 0.92461275315461 8 Q16881,Q8WUM4,P36507,P13639,P07900 5
Cargo concentration in the er 0.5151179671012265 1.3058077164349702 0.1916179552912946 1.0 0.9248344451084692 12 P49257,Q15436 2
Flt3 signaling in disease 0.6243902439024318 1.2965741187854762 0.1947777623170186 1.0 0.9248344451084692 6 Q06124,Q01082,P62993,Q9UBW7,P22681 5
Purine ribonucleoside monophosphate biosynthesis 0.5501850766354286 1.284683857805931 0.1989027813596331 1.0 0.9248344451084692 9 P31939,P49915,P30520,P22102 4
Signaling by scf kit 0.6217159245143088 1.284409146990237 0.1989988341323338 1.0 0.9248344451084692 6 P22681,P40763 2
Irf3 mediated induction of type i ifn 0.6426306698712791 1.2747046121719263 0.202413813759382 1.0 0.9248344451084692 5 P78527 1
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.8546488022736501 1.271506604384381 0.203548479398586 1.0 0.9248344451084692 3 Q13547,Q92769 2
Condensation of prometaphase chromosomes 0.5533044447012281 1.2638722887819405 0.2062758695137678 1.0 0.9248344451084692 8 O95347,Q15021,P19784,Q15003 4
Downstream signal transduction 0.6388894516032962 1.258138894470466 0.2083415291986692 1.0 0.9248344451084692 5 Q06124,P46109,P40763 3
Signaling by pdgf 0.6388894516032962 1.258138894470466 0.2083415291986692 1.0 0.9248344451084692 5 Q06124,P46109,P40763 3
Negative feedback regulation of mapk pathway 0.6899543650362238 1.256769084514014 0.2088372638052911 1.0 0.9248344451084692 4 P36507 1
Response of mtb to phagocytosis 0.4885468319577267 1.2508139308903858 0.2110023711023398 1.0 0.9248344451084692 13 P28482,O14964,Q9H267,P06733 4
Infection with mycobacterium tuberculosis 0.4885468319577267 1.2508139308903858 0.2110023711023398 1.0 0.9248344451084692 13 P28482,O14964,Q9H267,P06733 4
Ncam signaling for neurite out growth 0.6141047573493184 1.249779469596135 0.2113801177908272 1.0 0.9248344451084692 6 Q13813,P62993,O15020,P28482 4
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.6874694783961511 1.2463986458380127 0.2126180781580484 1.0 0.9248344451084692 4 Q99570,O14654 2
Mismatch repair 0.5486204324671892 1.2399732204271892 0.2149852993963938 1.0 0.9248344451084692 8 P20585,P52701,P12004,Q9Y2S7 4
Formation of tc ner pre incision complex 0.4276017939582031 1.2397223209589356 0.2150781182455925 1.0 0.9248344451084692 22 Q93009,Q9UNS2,P30876,P18074,P19447,P24928,Q13620,Q9BT78,P61201 9
Copii mediated vesicle transport 0.4277569331367099 1.2389352203973134 0.2153694890735986 1.0 0.9248344451084692 23 P49257,Q15436,Q9HCU5 3
Deadenylation dependent mrna decay 0.4250868027172046 1.2328037055558454 0.2176490085104894 1.0 0.9248344451084692 29 Q9NQT5,Q96C86,Q9Y450,Q6PGP7,Q9Y2L1,Q9Y333,Q8IZH2,Q9NPI6,Q96F86,Q04637 10
Growth hormone receptor signaling 0.6325127954517646 1.229902897592965 0.2187334690424527 1.0 0.926482528109752 5 P40763 1
Deactivation of the beta catenin transactivating complex 0.6073279107801806 1.2189424030152467 0.2228660541246312 1.0 0.930957330562342 6 Q13547,Q15291,Q9HCK8 3
Mrna decay by 3 to 5 exoribonuclease 0.4983428754413482 1.2100458073871811 0.2262613161502944 1.0 0.9345576101859988 12 Q9NQT5,Q96C86,Q9Y2L1,Q9Y450 4
Nucleotide salvage 0.6031197785751363 1.1997957940892685 0.2302186580411602 1.0 0.9450333802306888 6 P55263,P04183 2
Sphingolipid de novo biosynthesis 0.5308087842992851 1.1841085053109617 0.2363701137251932 1.0 0.9633034302169212 9 Q06136 1
Transcription of the hiv genome 0.4304481138326212 1.1823664596633143 0.2370603255819128 1.0 0.9633034302169212 17 P19447,P24928,Q08945,Q92804,Q9Y5B9 5
Rhobtb3 atpase cycle 0.8298122524057763 1.1790004954279534 0.2383979785564465 1.0 0.9633034302169212 3 O14964 1
Association of tric cct with target proteins during biosynthesis 0.4350662672869609 1.175638346831459 0.239739425114136 1.0 0.9633034302169212 16 Q15477,Q9Y2T2,P40227,Q99832,P40763,P48643,P49368,P17987,P50991,P61962,P78371 11
Bbsome mediated cargo targeting to cilium 0.5959349593495948 1.167115379350639 0.2431637778513988 1.0 0.9682868998274266 6 P48643,P49368,P17987,P50991,P78371 5
Leishmania infection 0.4132755707552886 1.1642858524225108 0.2443081879867201 1.0 0.9699399702159336 32 Q7L576,O15143,Q14185,P10644,Q9UQB8,P61160,P28482,P35579,Q9Y3E5,Q9Y2A7 10
Map2k and mapk activation 0.5189022136673007 1.158598843091724 0.2466197406863055 1.0 0.9721434906530836 10 P46940,P18206,P36507 3
Er to golgi anterograde transport 0.3136451048277114 1.1504739494055676 0.2499487177255719 1.0 0.9721434906530836 63 Q9HCU5,P53621,P49257,Q15436,P24390,P35606,Q92538,Q14203,P62820,Q14204 10
Metabolism of steroids 0.4020886855538015 1.1380120610338134 0.2551154460955815 1.0 0.9778200095306152 37 P53602,P14324,P51659,Q15436,O95772,Q13085,P30536,O00763,Q15392,P49327,Q9BWD1 11
Ripk1 mediated regulated necrosis 0.5338797246875756 1.1317774413598047 0.2577280140921461 1.0 0.9836624163775428 7 P07900,P49327 2
Signaling by erbb4 0.5848542486671502 1.116760063272622 0.2640969288269521 1.0 0.9843004311429446 6 Q15334,P61201 2
Transcription of e2f targets under negative control by dream complex 0.6549828498103315 1.1110160558192623 0.2665614383298087 1.0 0.9843004311429446 4 Q13547 1
Meiosis 0.4089295208437926 1.1082695300898506 0.2677454304697875 1.0 0.9843004311429446 21 P54132,O60934,Q14683,Q15554,Q9BTC0,P24941,P11802 7
Reproduction 0.4089295208437926 1.1082695300898506 0.2677454304697875 1.0 0.9843004311429446 21 P54132,O60934,Q14683,Q15554,Q9BTC0,P24941,P11802 7
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4462888813420623 1.0994125327349848 0.2715881666442181 1.0 0.9843004311429446 14 Q07864,P12004,P28340,Q9Y2S7,P09874,P39748 6
Mapk1 erk2 activation 0.8043036946812845 1.0844847058401788 0.2781499445451387 1.0 0.9843004311429446 3 P28482,P36507 2
Transport to the golgi and subsequent modification 0.3096742331938238 1.080155438812252 0.2800729679966598 1.0 0.9843004311429446 64 Q9HCU5,P53621,P49257,Q15436,P24390,P35606,Q92538,Q14203,P62820,Q14204 10
Diseases of dna repair 0.5170246414230167 1.0789527394703626 0.2806087963656885 1.0 0.9843004311429446 8 O60934,P52701,P54132 3
Formation of tubulin folding intermediates by cct tric 0.4593468445508472 1.0772333924958415 0.281376010671075 1.0 0.9843004311429446 13 P04350,P40227,Q99832,P48643,P49368,P17987,P68371,P50991,P78371,Q9BVA1 10
Interleukin 3 interleukin 5 and gm csf signaling 0.5756104469314505 1.0748211110746144 0.28245482685058 1.0 0.9843004311429446 6 P22681,P46109 2
Signal transduction by l1 0.5224489125232776 1.0745651289133102 0.2825694710892228 1.0 0.9843004311429446 7 P36507,P19784 2
Rho gtpases activate nadph oxidases 0.6458804766525912 1.0732122509837363 0.2831758952047565 1.0 0.9843004311429446 4 Q99570 1
Oncogene induced senescence 0.5741665157877989 1.0682774971302176 0.2853953560353215 1.0 0.9843004311429446 6 P28482,P11802 2
Prevention of phagosomal lysosomal fusion 0.6445810631982744 1.067822568893893 0.2856005555803755 1.0 0.9843004311429446 4 O14964 1
Rhobtb1 gtpase cycle 0.4068560739854023 1.0610728205779891 0.288656808624157 1.0 0.9905524900769794 18 Q7Z6E9,Q9UM54,Q5VTR2,P61201,Q8IYB3 5
Metabolism of steroid hormones 0.5929660710701676 1.0551359255270671 0.2913631635098364 1.0 0.9931162680311474 5 O95772 1
Suppression of phagosomal maturation 0.5182866359763654 1.0537696361372568 0.291988398267974 1.0 0.9931162680311474 7 O14964 1
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.7930988033009123 1.0432013163840617 0.2968550639420555 1.0 0.9931162680311474 3 P11802 1
Interaction between l1 and ankyrins 0.6352558895207137 1.0292043327840503 0.3033836667250966 1.0 0.9959269584432524 4 Q13813,O15020,Q12955 3
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.3986958612671578 1.0277071287125878 0.3040876135025578 1.0 0.9959269584432524 28 Q13451,Q14203,P08238,P31689,P68371,Q96FJ2,P0DMV9,P07900,P25685,Q9BVA1,Q9Y6G9,P11142,Q14204 13
Neurexins and neuroligins 0.5127632081108314 1.0262130017226554 0.3047911941635575 1.0 0.9959269584432524 7 Q15334 1
Polymerase switching on the c strand of the telomere 0.4657642700128639 1.02478613965487 0.3054641077500377 1.0 0.9959269584432524 12 P12004,P28340,P35251,P49643,Q9Y2S7,Q15554 6
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5853680876058098 1.0217173671971282 0.3069146888302201 1.0 0.9959269584432524 5 O95864 1
Vitamin b5 pantothenate metabolism 0.6320122214130541 1.0157990408150073 0.3097250928905215 1.0 0.9959269584432524 4 P49327 1
Notch1 intracellular domain regulates transcription 0.5620974734682906 1.0136838860764914 0.3107336155093148 1.0 0.9959269584432524 6 Q13547,Q92769 2
Lagging strand synthesis 0.462621891412643 1.0070281179275278 0.3139212621996212 1.0 0.9959269584432524 12 P12004,P28340,P35251,P49643,Q9Y2S7,P39748 6
Chromatin modifying enzymes 0.3191533305441441 1.006127579392479 0.3143542034860915 1.0 0.9959269584432524 57 O94776,Q15291,O75151,P51610,Q13330,Q03164,Q13547,Q9ULM3,Q86U86,Q99873,Q14839,P51532,P11802,Q92769,P29375,O14744,Q9Y4A5,Q96GM5,Q7LBC6 19
Polb dependent long patch base excision repair 0.7818598280803049 1.0019765705322825 0.316354908793524 1.0 0.9959269584432524 3 P09874 1
Negative regulation of nmda receptor mediated neuronal transmission 0.6284479021075118 1.0010870301037358 0.3167847348602508 1.0 0.9959269584432524 4 Q16566 1
Smad2 smad3 smad4 heterotrimer regulates transcription 0.7810981815371594 0.999190293418602 0.3177025170811896 1.0 0.9959269584432524 3 Q13547 1
Ca dependent events 0.5587782498844407 0.9987065879072112 0.3179368483816054 1.0 0.9959269584432524 6 P10644,Q16566 2
Base excision repair 0.3918000446288982 0.9860857968860112 0.3240910127181127 1.0 0.9959269584432524 21 Q07864,P12004,P29372,P28340,P35251,Q96T60,Q9Y2S7,P09874,P39748,Q15554 10
Signaling by flt3 fusion proteins 0.6238830219333906 0.982275577608362 0.3259641028733955 1.0 0.9959269584432524 4 P62993,Q01082,Q9UBW7 3
Signaling by braf and raf1 fusions 0.3903001974351365 0.9812733802266084 0.326457946208829 1.0 0.9959269584432524 20 Q7Z2W4,O15164,O00203,P46940,P28482,P36507,Q6WCQ1,P18206 8
Slc mediated transmembrane transport 0.3897598034555329 0.9774727123918852 0.3283351806242187 1.0 0.9959269584432524 20 P53985,Q99808,P04920 3
Formation of incision complex in gg ner 0.4904958939902904 0.9757999667320728 0.3291636012562668 1.0 0.9959269584432524 9 P09874,P19447,P54727,Q13620 4
Hdr through homologous recombination hrr 0.3940152724744481 0.9728591507981516 0.3306233096069237 1.0 0.9959269584432524 18 O60934,Q92547,P54132,Q07864,P12004,P28340,P35251,Q9Y2S7 8
Microrna mirna biogenesis 0.4830578226661866 0.9702433150865976 0.331925224743625 1.0 0.9959269584432524 10 Q9UPY3,Q9HAV4,P24928 3
Perk regulates gene expression 0.4689744030148786 0.9644284080841152 0.3348311853683574 1.0 0.9959269584432524 11 Q9Y2L1,P08243 2
Trafficking of ampa receptors 0.493072520793521 0.9576873832121282 0.3382204207163599 1.0 0.9974127706269597 8 Q15334 1
Global genome nucleotide excision repair gg ner 0.3883753810504048 0.9537076255916568 0.3402316591093792 1.0 0.999227509250762 29 Q07864,Q9UNS2,P12004,P18074,P19447,P28340,P35251,Q9Y2S7,P09874,P54727,Q13620,Q9BT78,P61201 13
Estrogen dependent nuclear events downstream of esr membrane signaling 0.7685660880478966 0.9534968483900744 0.3403383922485679 1.0 0.999227509250762 3 O14980 1
Hiv transcription initiation 0.4853099491611439 0.949221891845299 0.342507769589895 1.0 0.9993716331205472 9 P19447,Q92804,P24928 3
Diseases of mismatch repair mmr 0.7648108078116533 0.9398646613698683 0.3472869860403436 1.0 0.9993716331205472 3 P52701 1
Mecp2 regulates transcription of neuronal ligands 0.7643017991189901 0.938019171481986 0.3482345578403547 1.0 0.9993716331205472 3 Q13547 1
Notch hlh transcription pathway 0.6126879842214397 0.9363055056282464 0.3491159142867488 1.0 0.9993716331205472 4 Q13547,Q92769 2
Gluconeogenesis 0.3831264582376971 0.9309916439366646 0.3518578866049959 1.0 0.9993716331205472 20 P06744,P17174,P11498,P06733,P09972 5
Egfr downregulation 0.5375135680535712 0.903264773699582 0.3663853875454457 1.0 0.9993716331205472 6 P22681 1
Interleukin 7 signaling 0.8725649350649345 0.9015918767429392 0.3672737077704715 1.0 0.9993716331205472 2 P40763 1
Homology directed repair 0.3812398458205831 0.9005692879505482 0.367817370055169 1.0 0.9993716331205472 29 Q07864,P54132,O60934,Q92547,O60921,P12004,P28340,P35251,Q9Y2S7,P09874,P39748,P24941,Q14676 13
Cargo recognition for clathrin mediated endocytosis 0.3788054335825783 0.8800300700290653 0.3788430199939423 1.0 1.0 25 P61201,P22681,O43493,Q00610 4
Telomere c strand synthesis initiation 0.5987002437042992 0.879256498861722 0.3792622166518675 1.0 1.0 4 P49643,Q15554,Q9NYB0 3
P75ntr negatively regulates cell cycle via sc1 0.8660714285714333 0.8790695158381662 0.3793635851810495 1.0 1.0 2 Q13547 1
Nucleotide excision repair 0.3644787280375177 0.8763601646189892 0.380834266992331 1.0 1.0 40 Q07864,Q93009,Q9UNS2,P30876,P12004,P18074,P19447,P28340,P35251,Q9Y2S7,P24928,P09874,P54727,Q13620,Q9BT78,Q9HCS7,P61201 17
Miscellaneous transport and binding events 0.5516936583375127 0.8748710141191098 0.3816440921727002 1.0 1.0 5 Q9UNS2,Q9H0U3 2
Mrna decay by 5 to 3 exoribonuclease 0.4818581983974366 0.873265734252593 0.3825182528959816 1.0 1.0 7 Q9NPI6,Q96F86,Q8IZH2 3
Transcription coupled nucleotide excision repair tc ner 0.3726230516796047 0.8647844863682527 0.3871570875736394 1.0 1.0 34 Q07864,Q93009,Q9UNS2,P30876,P12004,P18074,P19447,P28340,P35251,Q9Y2S7,P24928,Q13620,Q9BT78,Q9HCS7,P61201 15
Regulation of cholesterol biosynthesis by srebp srebf 0.3733105595243411 0.8564845080062531 0.3917298383395604 1.0 1.0 21 P53602,O76062,P14324,P53992,Q15436,Q13085,O00763,P49327 8
Pi3k akt signaling in cancer 0.475088615582612 0.8401554625841305 0.4008212262658845 1.0 1.0 7 P42345,P49841,Q06124,Q9NWH9 4
Dag and ip3 signaling 0.5213707530301147 0.8315916596388601 0.4056394714029345 1.0 1.0 6 Q16566 1
Met activates rap1 and rac1 0.5413508833261181 0.8303486848942432 0.4063416695935893 1.0 1.0 5 P62993,Q9NWH9,P46109 3
Uptake and function of anthrax toxins 0.7297236072285374 0.814140655423667 0.4155643777321411 1.0 1.0 3 P36507 1
Signaling by fgfr2 0.3648355446207401 0.8124562706244676 0.4165298690255659 1.0 1.0 19 P30876,P52272,P24928,P28482,P22681 5
Signaling by fgfr 0.3648355446207401 0.8124562706244676 0.4165298690255659 1.0 1.0 19 P30876,P52272,P24928,P28482,P22681 5
Interleukin 20 family signaling 0.7286842704790651 0.8104690954345476 0.4176706200922782 1.0 1.0 3 P40763 1
Gap junction degradation 0.5354509899440543 0.8051116499453159 0.4207552536314305 1.0 1.0 5 Q00610 1
Transcriptional regulation of granulopoiesis 0.4674667600702044 0.803102026215716 0.4219157666789725 1.0 1.0 7 P24941,P11802,P40763,P35659 4
Oas antiviral response 0.7262294580203479 0.8018109285515498 0.4226623359906809 1.0 1.0 3 P21333 1
Hiv transcription elongation 0.3778487720407818 0.8007044716696471 0.423302753209799 1.0 1.0 16 P19447,Q08945,Q9Y5B9,P24928 4
Aryl hydrocarbon receptor signalling 0.7246655533426527 0.7963052199745547 0.4258546522863373 1.0 1.0 3 O00170 1
Influenza infection 0.3684983067693814 0.7830782606010417 0.4335811563514813 1.0 1.0 119 P83881,P27635,P24928,P09874,P61313,P18621,P08708,P62910,P62266,O00629,P42766,P40429,P18077,Q02878,P60866,Q9Y3U8,O14980,P62917,Q00610,P07900,Q07020,Q02543,P30876,P36578,P12270,P62899,P35658 27
Estrogen dependent gene expression 0.3639111990963964 0.7776268477483086 0.4367890287809797 1.0 1.0 24 P30876,P08238,Q14683,Q13547,O14646,P24928,Q99873,P07900,Q9UQE7 9
Creatine metabolism 0.8352272727272745 0.7738155777792497 0.4390398590692574 1.0 1.0 2 P12277 1
Regulation of pten gene transcription 0.3734696236202409 0.7729482694698548 0.4395529963192699 1.0 1.0 16 O94776,Q13547,Q92769,P28482,Q14839,Q13330 6
Ptk6 regulates cell cycle 0.8348214285714279 0.7724519053298992 0.4398468217274427 1.0 1.0 2 P11802 1
Polymerase switching 0.4443014826323244 0.7707584075425036 0.4408501446632251 1.0 1.0 10 P12004,P28340,P35251,P49643,Q9Y2S7 5
Sema4d in semaphorin signaling 0.4548248180226096 0.7675882432445977 0.4427318493036383 1.0 1.0 8 Q7Z406,P35580,Q9NWH9,P35579 4
Constitutive signaling by aberrant pi3k in cancer 0.5695976869844149 0.7623970167287001 0.4458230862337105 1.0 1.0 4 Q06124,Q9NWH9 2
Oncogenic mapk signaling 0.3613569238337774 0.7599895182030497 0.4472608503398974 1.0 1.0 24 Q7Z2W4,O15164,O00203,P21359,P46940,P28482,P36507,Q6WCQ1,P18206 9
Tp53 regulates transcription of cell cycle genes 0.4411074615369952 0.7546447172257712 0.4504621851142327 1.0 1.0 10 P24941,A5YKK6,Q99873,P12004 4
Sars cov 2 infection 0.3578551758538476 0.7508550823894614 0.4527398752871465 1.0 1.0 21 Q9H0U3,Q99570 2
Antigen processing ubiquitination proteasome degradation 0.3007639028885754 0.7395235426339604 0.4595891494086177 1.0 1.0 76 Q9ULT8,Q15386,P49427,A0AVT1,Q7Z6E9,Q13867,Q13200,P51665,O95376,Q7Z6Z7 10
Scavenging by class f receptors 0.5629738884803112 0.7362331339427928 0.4615888310730347 1.0 1.0 4 Q9Y4L1 1
Fatty acyl coa biosynthesis 0.3858450503342255 0.7326439181562757 0.4637756373547979 1.0 1.0 14 P53396,Q9NZ01,Q9P035,Q13085,P49327 5
Signaling by csf3 g csf 0.4524750255630432 0.7310470253431544 0.4647504299534792 1.0 1.0 7 Q93034,P62993,Q06124,P40763 4
Purine salvage 0.5170975060969727 0.7274876043687589 0.4669273060719754 1.0 1.0 5 P55263 1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.4394603062643123 0.7187905161864182 0.4722700019492216 1.0 1.0 9 Q03164,Q15291,Q96ST3,Q13547,Q99873 5
Nephrin family interactions 0.495344342010581 0.7180777413966267 0.4727093536996565 1.0 1.0 6 P46940,O43707 2
Hiv elongation arrest and recovery 0.3953929474178299 0.7075040800448662 0.47925327809092 1.0 1.0 13 Q08945,Q9Y5B9,P24928 3
Regulation of runx1 expression and activity 0.6981838699716396 0.7044109923604529 0.481176862390791 1.0 1.0 3 Q06124 1
Regulation of signaling by cbl 0.6975794308801737 0.7023456867007443 0.4824636080009656 1.0 1.0 3 P22681 1
Condensation of prophase chromosomes 0.4408613558287051 0.6999557510371982 0.4839549386994748 1.0 1.0 8 O95347,Q01105,P42695 3
Synthesis of very long chain fatty acyl coas 0.4898900223089845 0.6946923481205612 0.4872481244160345 1.0 1.0 6 Q9P035,Q9NZ01,O60488 3
Piwi interacting rna pirna biogenesis 0.4421855685135397 0.6823493018903717 0.4950181052033331 1.0 1.0 7 P07900,P24928 2
Dna double strand break repair 0.3414440118386767 0.6774953637427304 0.498091710679869 1.0 1.0 39 Q07864,P54132,O60934,Q92547,P12004,P13010,P28340,P35251,P78527,Q9Y2S7,P09874,P39748,P24941,Q14676 14
Interleukin 37 signaling 0.8039772727272718 0.6707289200996985 0.5023932358661864 1.0 1.0 2 P40763 1
Signaling by leptin 0.8039772727272718 0.6707289200996985 0.5023932358661864 1.0 1.0 2 P40763 1
Signaling by vegf 0.3430910300279455 0.6683177696629534 0.5039307728151903 1.0 1.0 19 Q7L576,Q14185,Q9UQB8,P07900 4
Endosomal sorting complex required for transport escrt 0.4340711914442784 0.6675323755535529 0.5044321367849158 1.0 1.0 8 Q9UN37 1
Irs mediated signalling 0.6853430775476952 0.6608820573359191 0.5086879536026474 1.0 1.0 3 Q06124,Q99570 2
Met activates ptpn11 0.6853430775476879 0.6608820573358949 0.508687953602663 1.0 1.0 3 Q06124,Q9NWH9 2
Met receptor recycling 0.6853430775476876 0.6608820573358946 0.5086879536026632 1.0 1.0 3 Q9NWH9,P46109 2
Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.5434118122521184 0.6601382180964557 0.5091651350201816 1.0 1.0 4 P35659 1
Toll like receptor cascades 0.3393104907082175 0.6440085583035337 0.5195698843155321 1.0 1.0 19 Q06124,P09429,Q9BQ95,P28482,Q99570 5
Rna polymerase i transcription termination 0.4183556701198926 0.6419170900480529 0.520927017168082 1.0 1.0 10 P17480,P19447,O95602,Q3B726 4
Extension of telomeres 0.3420916161321175 0.6403246322019469 0.5219615699552937 1.0 1.0 22 P54132,P40938,P12004,O60832,P28340,P35251,P49643,Q9Y2S7,P39748,Q15554,P24941 11
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4317783694937647 0.6338407124454907 0.5261847806593183 1.0 1.0 7 P63241 1
Formation of the beta catenin tcf transactivating complex 0.4209638287823841 0.6293389039425538 0.5291272069279496 1.0 1.0 9 Q13547,P51532,Q9Y4A5 3
Dual incision in tc ner 0.3423969566609106 0.6259688678545856 0.5313353614598166 1.0 1.0 26 Q07864,Q93009,P30876,P12004,P18074,P19447,P28340,P35251,Q9Y2S7,P24928,Q13620 11
Hdr through single strand annealing ssa 0.3925284340245479 0.6240484283959069 0.5325957810746613 1.0 1.0 12 O60934,Q92547 2
Homologous dna pairing and strand exchange 0.3925284340245479 0.6240484283959069 0.5325957810746613 1.0 1.0 12 O60934,Q92547 2
Transcriptional activation of mitochondrial biogenesis 0.4141074360218851 0.6213321185664165 0.5343811251387254 1.0 1.0 10 O00411 1
Rho gtpases activate cit 0.4188447482449193 0.6192683466746212 0.5357395932455491 1.0 1.0 9 Q15334,P35579 2
Apoptosis induced dna fragmentation 0.4124576348648991 0.6133827956301713 0.5396232591146719 1.0 1.0 10 P09429 1
Regulated necrosis 0.3772248782620981 0.6082255431281542 0.543037895674678 1.0 1.0 13 P07900,P49327,P09429 3
Carnitine metabolism 0.4855073390039277 0.5979179620092593 0.5498946741167039 1.0 1.0 5 Q13085 1
Integration of energy metabolism 0.3357228836846705 0.5937590152109401 0.5526733049461947 1.0 1.0 23 P53396,P10644,Q13085,P46940,O00763,P49327 6
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.4842899313203106 0.5930499843526968 0.5531477013337096 1.0 1.0 5 Q99808 1
Glucuronidation 0.663151367338777 0.5875464309104026 0.5568367765293047 1.0 1.0 3 O60701 1
Signaling by moderate kinase activity braf mutants 0.3950474390324196 0.5795748274077569 0.5622013724854391 1.0 1.0 11 P46940,P18206,P36507 3
Regulation of innate immune responses to cytosolic dna 0.6570976149833138 0.5680052315384765 0.5700314156189425 1.0 1.0 3 P19474 1
Rhov gtpase cycle 0.3696205451503777 0.5678690849663987 0.5701238652881939 1.0 1.0 13 P46940,Q93008,Q96KM6,Q00610 4
Rna polymerase i transcription 0.3291546152815816 0.5579776541866409 0.5768596432063813 1.0 1.0 22 O94776,O95602,Q3B726,P17480,P19447,Q13547,Q92769,Q14839,Q13330 9
Ksrp khsrp binds and destabilizes mrna 0.4056107521829494 0.5573366464284694 0.5772974420076449 1.0 1.0 9 Q9Y2L1 1
Rho gtpases activate paks 0.3984834680947656 0.547149092739431 0.5842763070132135 1.0 1.0 10 P21333,P35579 2
Eph ephrin signaling 0.3297071523702053 0.5467892830141522 0.5845235066727152 1.0 1.0 25 P35580,Q00610,O15143,P35579 4
Rab regulation of trafficking 0.329978285088755 0.5453061185857383 0.5855429966396224 1.0 1.0 26 Q9UL25,Q7Z392,Q8TC07,P62820 4
Dna damage bypass 0.3271319814184005 0.539942056203089 0.5892369931850427 1.0 1.0 18 Q07864,P40938,P12004,P28340,P35251,P55072,Q9Y2S7,Q8TAT6,Q13620 9
Ret signaling 0.6482236876992136 0.5397555019853348 0.589365658194756 1.0 1.0 3 Q06124 1
Rac2 gtpase cycle 0.32950091596644 0.5381419203889729 0.5904790733585135 1.0 1.0 30 Q14185 1
Gap junction trafficking and regulation 0.386426473146182 0.5377547916359057 0.5907463466661638 1.0 1.0 11 Q07157,Q9UM54,Q00610 3
Meiotic recombination 0.401082485647014 0.5365590349707324 0.591572247150137 1.0 1.0 9 O60934,P54132,P11802 3
Toll like receptor 9 tlr9 cascade 0.3345540193948356 0.5188411211193952 0.6038715395613989 1.0 1.0 15 Q99570,P09429 2
Negative regulation of the pi3k akt network 0.3971719326043974 0.5188008199281386 0.6038996460953936 1.0 1.0 9 P28482,Q06124,Q14738,Q9NWH9 4
Transport of vitamins nucleosides and related molecules 0.4004206345159649 0.5126560439910137 0.6081919424241466 1.0 1.0 8 P12235,Q99808 2
Translation of sars cov 2 structural proteins 0.3299763101823121 0.5114544059248357 0.6090329067886819 1.0 1.0 16 Q9H0U3 1
Assembly of collagen fibrils and other multimeric structures 0.6361335039729588 0.5020731592923684 0.6156160598146165 1.0 1.0 3 Q15149 1
Signaling by egfr 0.3979483609400442 0.5017334501586712 0.6158550314686329 1.0 1.0 8 P22681 1
Aggrephagy 0.32949800770264 0.490915240796664 0.6234863970962556 1.0 1.0 15 Q96FJ2,P07900,Q9BVA1,Q9Y6G9,Q14204 5
Protein methylation 0.3983480480633263 0.4845011903548604 0.6280302197623824 1.0 1.0 7 P13639,P11142,O60678 3
Mitotic g1 phase and g1 s transition 0.2619943720167543 0.4843517658380563 0.6281362437642619 1.0 1.0 67 Q07864,Q13200,P04183,P24941,P49736,P12004,P62333,Q13547,O43913,P33993,P33991,P11802,O43242,P25205,P51665,P33992,O00487,P49643,P62191,Q15008,Q13416 21
Signal attenuation 0.6296828739108722 0.4823731457291529 0.6295408943487861 1.0 1.0 3 P28482 1
Cell cell communication 0.3163613895285379 0.480386253935169 0.6309527668217378 1.0 1.0 22 Q06124,P62993,P19022,P21333,Q9BY67,P55196,P46940,Q15149,Q13813,O43707 10
Rho gtpase effectors 0.3011446684556299 0.4754542281259014 0.6344632504198813 1.0 1.0 93 O15143,P21333,P43034,P46940,Q99570,Q9Y2A7,Q86UP2,Q15334,Q9P258,P35580,Q14204,Q7L576,O14980,O75122,Q9UQB8,P33176,P28482,Q9HD26,P35579,Q9BVA1,Q16513,P61160,Q96FJ2,P46060,Q14008 25
Regulation of expression of slits and robos 0.3338715844457862 0.4691348114994161 0.6389732776706827 1.0 1.0 117 P27635,Q13200,P61313,P18621,P08708,P62910,P62266,P18077,Q02878,P60866,Q9Y3U8,Q9BZI7,P15170,P62917,P51665,Q02543,P36578,P62899,Q04637 19
Apoptotic cleavage of cell adhesion proteins 0.4511033969873211 0.4648945478597729 0.6420069751098554 1.0 1.0 5 P15924 1
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.7345779220779206 0.4596685887991703 0.6457541191542391 1.0 1.0 2 Q96T60 1
Activation of gene expression by srebf srebp 0.3170205881878307 0.4591730814016019 0.6461098794475209 1.0 1.0 17 P53602,P14324,Q13085,O00763,P49327 5
Nuclear signaling by erbb4 0.6181313358956153 0.4478474234378866 0.6542633151376003 1.0 1.0 3 P61201 1
Processing of dna double strand break ends 0.3074850275894226 0.4432418664500617 0.6575907993906638 1.0 1.0 20 P54132,Q92547,O60934,Q14676 4
Cytosolic sensors of pathogen associated dna 0.331958689326998 0.4369542190721703 0.6621445497602081 1.0 1.0 14 Q9H2U1,P78527,P13010 3
Downregulation of erbb2 signaling 0.4805064717925416 0.4319312458590775 0.6657913844479646 1.0 1.0 4 P07900 1
Resolution of sister chromatid cohesion 0.2874873641779815 0.4262207330446462 0.6699470112255046 1.0 1.0 49 O14980,O75122,Q14683,P49792,Q14738,Q29RF7,Q15691,P43034,Q9NTI5,Q96FJ2,P46060,Q14008,Q9P258,Q9BVA1,Q9UQE7,Q9Y6G9,Q14204 17
Negative epigenetic regulation of rrna expression 0.3055516704507907 0.4123672491650318 0.6800702644369232 1.0 1.0 23 O95602,Q3B726,Q96ST3,P19447,Q13547,Q92769,P26358 7
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3113799695806594 0.4106851145050086 0.6813034432890048 1.0 1.0 16 Q07864,P40938,P12004,P28340,P35251,P55072,Q9Y2S7,Q8TAT6 8
G1 s specific transcription 0.3722469275065843 0.4101907469933253 0.6816660280182234 1.0 1.0 9 Q13547,P04183 2
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3138532351890746 0.4080898512244082 0.6832077106106467 1.0 1.0 15 O43493 1
Rhof gtpase cycle 0.3258098348183025 0.406513755318868 0.6843651521791181 1.0 1.0 14 P80723,Q5JTV8 2
Epigenetic regulation of gene expression 0.3019611563608335 0.4052317253975933 0.6853071869881968 1.0 1.0 40 O94776,P49841,O95602,Q3B726,P18074,P17480,P19447,Q13547,Q92769,Q96ST3,O00159,O75533,Q9BQG0,P35659,P26358,Q9NR30,Q14839,Q13330 18
Trna processing in the mitochondrion 0.4718409936863997 0.4030926612570224 0.686880059172049 1.0 1.0 4 Q7L0Y3 1
Intracellular signaling by second messengers 0.2581929937447859 0.4023274869095692 0.6874430282134851 1.0 1.0 70 O94776,Q13200,Q13330,Q93009,P62333,Q13547,O75832,Q14839,O43242,P10644,Q92769,P28482,P51665,P55036,Q9HCE1,Q16566,Q06124,O00487,P49841,P42345,Q15022,P19784,Q14738,Q15008,Q9NWH9,P62191,P25787 27
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5992691839220512 0.3937099554375019 0.6937951904435216 1.0 1.0 3 P07900,P35270 2
Rho gtpases activate rocks 0.3717616150141035 0.3908735577795967 0.695890700042846 1.0 1.0 8 Q7Z406,P35580,P35579 3
S phase 0.2691374225296498 0.3887749496632741 0.6974426331822752 1.0 1.0 78 Q07864,Q13200,P39748,P24941,P49736,P12004,P62333,O43913,Q9NTI5,O75832,P33993,P33991,P11802,O43242,P25205,P28340,P35251,Q29RF7,P51665,P55036,P40938,P33992,O00487,Q14683,P49643,P62191,Q15008,Q9Y2S7,Q13416,Q9UQE7 30
Signaling by erbb2 in cancer 0.4671027349931915 0.3876476219830411 0.6982768220421092 1.0 1.0 4 P07900 1
Constitutive signaling by overexpressed erbb2 0.4671027349931915 0.3876476219830411 0.6982768220421092 1.0 1.0 4 P07900 1
Signaling by erbb2 ecd mutants 0.4671027349931915 0.3876476219830411 0.6982768220421092 1.0 1.0 4 P07900 1
Ngf stimulated transcription 0.5964271213966663 0.3858092715155091 0.6996379282623284 1.0 1.0 3 Q00535,Q14839 2
Response of eif2ak1 hri to heme deficiency 0.5964153248369095 0.385776623693327 0.6996621092985722 1.0 1.0 3 P08243 1
Semaphorin interactions 0.2995095152215739 0.3855426281806323 0.6998354300462171 1.0 1.0 18 P08238,Q9NWH9,Q7Z406,P35579,P07900,P35580 6
Hdacs deacetylate histones 0.3323799651558176 0.3837597270254775 0.7011565398849513 1.0 1.0 13 O94776,Q13547,Q92769,Q14839,Q13330 5
Rhog gtpase cycle 0.3042238878123666 0.3833345620775599 0.7014717160199435 1.0 1.0 32 Q14185 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.3059472894185314 0.3828964453316631 0.7017965471066288 1.0 1.0 16 P04350,P40227,O15212,Q99832,P48643,P49368,P17987,P68371,P50991,P78371,Q9BVA1 11
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.5950195308596918 0.3819222230223232 0.7025190559684686 1.0 1.0 3 P40763 1
Signaling by kit in disease 0.5950195308596918 0.3819222230223232 0.7025190559684686 1.0 1.0 3 P40763 1
Interleukin 2 family signaling 0.5950195308596918 0.3819222230223232 0.7025190559684686 1.0 1.0 3 P40763 1
Rhobtb gtpase cycle 0.3022195486385168 0.3801906764417424 0.703803879678105 1.0 1.0 26 Q7Z6E9,Q9UM54,Q5VTR2,Q13618,P61201,Q8IYB3 6
Factors involved in megakaryocyte development and platelet production 0.297749044556683 0.3782224489949305 0.7052653500969113 1.0 1.0 40 Q96ST3,Q14185,Q13547,P10644,Q92769,P33176,Q9H4M9,O95239,P24941,Q9BVA1 10
Negative regulation of mapk pathway 0.3600856405806054 0.3777843615340238 0.7055907919888047 1.0 1.0 10 P28482,P36507 2
Epha mediated growth cone collapse 0.4094167773388552 0.375875000445538 0.7070098267434628 1.0 1.0 6 Q7Z406,P35580,P35579 3
Sema4d induced cell migration and growth cone collapse 0.4094167773388552 0.375875000445538 0.7070098267434628 1.0 1.0 6 Q7Z406,P35580,P35579 3
Free fatty acids regulate insulin secretion 0.7033279220779203 0.3752247751407294 0.7074933061389845 1.0 1.0 2 O60488 1
Signaling by notch1 pest domain mutants in cancer 0.3716693577505652 0.3746625983017142 0.7079114116053171 1.0 1.0 7 Q13547,Q92769 2
Translesion synthesis by polh 0.3582613101092914 0.370295745234889 0.7111621436777136 1.0 1.0 10 Q8TAT6,P35251,P40938,P12004 4
Signaling by erbb2 0.3695956452013988 0.3665515610227561 0.7139535454801182 1.0 1.0 7 Q93034,P07900,O60610 3
Class i mhc mediated antigen processing presentation 0.2899917523686161 0.3639839452788125 0.7158699981047048 1.0 1.0 94 Q9ULT8,Q15386,P49427,A0AVT1,Q7Z6E9,P09429,Q13867,Q13200,Q15436,P51665,O95376,Q7Z6Z7 12
Recognition of dna damage by pcna containing replication complex 0.3265736389105091 0.3575099295472098 0.7207100940178464 1.0 1.0 13 Q07864,P12004,P28340,Q9Y2S7,Q13620 5
Pcna dependent long patch base excision repair 0.3255406824607446 0.3529202901798222 0.724148199009413 1.0 1.0 13 Q07864,P12004,P28340,Q9Y2S7,P39748 5
Rna polymerase iii transcription 0.3557788274815212 0.3435047582654616 0.7312187617859509 1.0 1.0 9 Q9Y5Q9,Q12789 2
Signaling by receptor tyrosine kinases 0.2856660207904518 0.3401865679134664 0.733716032879572 1.0 1.0 93 Q14185,P52272,P24928,Q99570,P38606,Q9Y2A7,Q13547,P40763,Q15334,P22681,P36507,Q14839,Q7L576,O14964,Q9UQB8,Q92769,P46109,P28482,Q00610,P07900,O14654,P30876,P16949,Q96ST3,Q9NWH9,P61201 26
Nonhomologous end joining nhej 0.3226151062294328 0.3400568079148433 0.7338137477590616 1.0 1.0 13 O60934,P78527,Q14676 3
Positive epigenetic regulation of rrna expression 0.2933884749252468 0.3296505857999598 0.7416639951777457 1.0 1.0 27 O94776,O95602,Q3B726,Q13547,O75533,Q92769,O00159,Q9BQG0,P35659,Q14839,Q9NR30,Q13330 12
Interleukin 15 signaling 0.6850649350649463 0.3295926121272611 0.7417078056305095 1.0 1.0 2 P40763 1
Pi 3k cascade fgfr2 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Downstream signaling of activated fgfr4 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Tie2 signaling 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Downstream signaling of activated fgfr1 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Frs mediated fgfr1 signaling 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr1 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Activated ntrk2 signals through frs2 and frs3 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Stat5 activation 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Frs mediated fgfr4 signaling 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr4 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Pi 3k cascade fgfr3 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Downstream signaling of activated fgfr2 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Signaling by flt3 itd and tkd mutants 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Stat5 activation downstream of flt3 itd mutants 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Signal regulatory protein family interactions 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Frs mediated fgfr3 signaling 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Frs mediated fgfr2 signaling 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Downstream signaling of activated fgfr3 0.6850649350649332 0.3295926121272297 0.7417078056305333 1.0 1.0 2 Q06124 1
Signaling by erythropoietin 0.685064935064933 0.3295926121272285 0.7417078056305342 1.0 1.0 2 P46109 1
Erythropoietin activates ras 0.685064935064933 0.3295926121272285 0.7417078056305342 1.0 1.0 2 P46109 1
Type i hemidesmosome assembly 0.684659090909108 0.3286119451033701 0.7424490181858605 1.0 1.0 2 Q15149 1
Aurka activation by tpx2 0.2919584296609892 0.3256649719507644 0.7446778489619938 1.0 1.0 26 P43034,Q14008,Q14203,Q15154,Q14204 5
Golgi associated vesicle biogenesis 0.292161576355688 0.3233115179639263 0.7464593319576036 1.0 1.0 27 O43493,Q92572 2
Galactose catabolism 0.6822240259740239 0.3227592279171146 0.7468775931356602 1.0 1.0 2 P51570 1
Maturation of sars cov 2 nucleoprotein 0.405774639293188 0.3080729049708721 0.7580268579059475 1.0 1.0 5 Q96SB4,Q99873 2
Sema3a pak dependent axon repulsion 0.4041546578536168 0.3029481068610752 0.7619294089439519 1.0 1.0 5 P07900 1
Josephin domain dubs 0.6712662337662388 0.2970962711501448 0.7663930111107631 1.0 1.0 2 P54727 1
Trans golgi network vesicle budding 0.2876379064843682 0.2928261907907633 0.7696550079538831 1.0 1.0 33 O14964,O43493,Q92538,Q00610,Q92572 5
Signaling by notch1 0.3460693433634186 0.2923514655561957 0.7700179128155011 1.0 1.0 8 Q13547,Q92769,Q9BZK7 3
Regulation of ifna signaling 0.5598863174989908 0.2908387379547132 0.7711746567304878 1.0 1.0 3 P18031,Q06124 2
Regulation of ifng signaling 0.5598863174989908 0.2908387379547132 0.7711746567304878 1.0 1.0 3 P18031,Q06124 2
Dna damage reversal 0.6655844155844135 0.2842329757698084 0.7762318461155253 1.0 1.0 2 Q8N3C0 1
Hats acetylate histones 0.2749093593582856 0.2841689342447929 0.7762809213862705 1.0 1.0 19 Q9ULM3 1
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.381933656760102 0.2833512679600725 0.7769075806868704 1.0 1.0 6 P12004 1
Rna polymerase ii transcribes snrna genes 0.2836310997091829 0.2779207552856698 0.7810731908994681 1.0 1.0 16 Q9BXP5,Q8N201,P24928 3
Gap filling dna repair synthesis and ligation in gg ner 0.3161367212811905 0.2732213192959134 0.7846830928016972 1.0 1.0 12 Q07864,P12004,P28340,P35251,Q9Y2S7,P49916 6
Aspartate and asparagine metabolism 0.3943918162913792 0.2728567111944376 0.7849633636840503 1.0 1.0 5 P08243 1
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3403254193549103 0.2719516706104517 0.7856591804657713 1.0 1.0 8 P07900,P09429 2
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.3918175837749691 0.2651551545265182 0.7908899402097715 1.0 1.0 5 O60934 1
Resolution of d loop structures 0.3918175837749691 0.2651551545265182 0.7908899402097715 1.0 1.0 5 O60934 1
Mrna capping 0.329770733574603 0.2614111734260321 0.7937754413843232 1.0 1.0 10 P19447,P24928 2
Met promotes cell motility 0.3404942006178769 0.2603747813346361 0.7945746938321909 1.0 1.0 7 Q9NWH9 1
Rab gefs exchange gtp for gdp on rabs 0.2723429382157156 0.2586436307307649 0.79591021592114 1.0 1.0 21 Q9UL25,Q7Z392 2
Transcriptional regulation by tp53 0.2706263831560632 0.2578591965472515 0.7965155765732796 1.0 1.0 90 P54132,O94776,P06744,P19447,P24928,A5YKK6,P24941,Q9NVI1,O60934,Q92547,Q93009,P12004,Q16881,Q13547,Q08945,Q99873,Q14839,Q92804,Q14676,Q9NYV4,Q92769,Q9HCE1,P30876,O60921,P18074,O14744,P19784,P49327,P42704,Q9Y5B9 30
Glycogen metabolism 0.3390935708423866 0.2556545539736519 0.7982175898134585 1.0 1.0 7 P35573 1
Circadian clock 0.3317053317053328 0.25482185834233 0.79886069193768 1.0 1.0 9 P63208,Q86X55,P62136,Q13616,P43490,Q9BZK7,P62140,Q96EB6 8
Tnf signaling 0.651785714285712 0.2542920579193277 0.7992699350512704 1.0 1.0 2 Q96BN8 1
Regulation of tnfr1 signaling 0.651785714285712 0.2542920579193277 0.7992699350512704 1.0 1.0 2 Q96BN8 1
Nr1h2 and nr1h3 mediated signaling 0.3718910232758781 0.2523355875713406 0.8007816829929373 1.0 1.0 6 P49327,Q9BZK7 2
Orc1 removal from chromatin 0.2619185503605024 0.2401384972303045 0.8102228907339168 1.0 1.0 48 O43242,P33992,P25205,O00487,P62333,Q13200,P55036,P62191,Q15008,O43913,O75832,P33993,P33991,P51665,P24941,Q13416,P49736 17
Grb2 sos provides linkage to mapk signaling for integrins 0.6428571428571406 0.2359222568218277 0.8134929972265397 1.0 1.0 2 P62993 1
Meiotic synapsis 0.2866369230642342 0.235233082300363 0.8140278303316484 1.0 1.0 14 Q15554,Q14683 2
Signaling by robo receptors 0.3169609071753534 0.2307697513939054 0.8174936818799567 1.0 1.0 128 P27635,Q13200,P61313,P18621,P08708,P62910,P62266,P18077,Q02878,P60866,Q9Y3U8,Q9BZI7,P15170,O75122,P62917,P51665,Q02543,P36578,P62899,Q04637 20
Synthesis of pc 0.531635136733795 0.2266586090888658 0.8206892146171483 1.0 1.0 3 P35790 1
Anchoring of the basal body to the plasma membrane 0.2700409855868 0.2198286618513479 0.8260045966561422 1.0 1.0 27 P43034,Q14008,Q14203,Q15154,Q14204 5
Regulation of plk1 activity at g2 m transition 0.2717024269236263 0.2192424356902908 0.8264612005950351 1.0 1.0 30 P43034,Q14008,Q14203,Q15154,Q14204 5
Assembly and cell surface presentation of nmda receptors 0.3262132787255294 0.2140855852952126 0.8304803164794117 1.0 1.0 7 Q9BVA1,Q15334 2
Regulation of tp53 expression and degradation 0.3259850881996103 0.213379820096545 0.8310307192915305 1.0 1.0 7 Q93009,P24941 2
Processing and activation of sumo 0.6241883116883093 0.2001318998459202 0.8413774255405524 1.0 1.0 2 Q9UBE0 1
Sumo is conjugated to e1 uba2 sae1 0.6241883116883093 0.2001318998459202 0.8413774255405524 1.0 1.0 2 Q9UBE0 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.6241883116883093 0.2001318998459202 0.8413774255405524 1.0 1.0 2 Q9UBE0 1
Pten regulation 0.2381969836730477 0.199704035839808 0.8417120572142531 1.0 1.0 55 O94776,Q13200,Q13330,Q93009,P62333,Q13547,O75832,Q14839,O43242,Q92769,P28482,P51665,P55036,Q9HCE1,O00487,P42345,Q15022,P19784,P62191,Q15008 20
Rac1 gtpase cycle 0.266095683505439 0.1935342419481673 0.8465405917463573 1.0 1.0 36 Q7L576,Q14185,Q9UQB8,P46940,Q16513,Q9Y2A7 6
Inactivation of csf3 g csf signaling 0.3646839420197483 0.190292226992737 0.8490801443293523 1.0 1.0 5 Q93034,P40763 2
Glycogen breakdown glycogenolysis 0.3634482376487495 0.1871698165072259 0.8515274895443763 1.0 1.0 5 P35573 1
Mitotic prometaphase 0.2381564062226588 0.1859327407476347 0.8524975064610012 1.0 1.0 75 P43034,Q15003,Q14203,O95347,Q9NTI5,Q9HC35,Q9P258,Q9NTJ3,Q14204,O14980,O75122,P49792,Q29RF7,Q15021,P07900,Q9BVA1,Q14683,P19784,Q14738,Q96FJ2,P46060,Q14008,Q15154,Q9UQE7,Q9Y6G9 25
Clathrin mediated endocytosis 0.2592474437707416 0.185618062588267 0.8527442878287075 1.0 1.0 43 P61201,P22681,O43493,Q00610 4
Signaling by ntrk2 trkb 0.3937208335566694 0.1835063513057747 0.8544007357725862 1.0 1.0 4 P62993,Q06124 2
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.2526751830604767 0.1813677351233077 0.856078942504646 1.0 1.0 47 P20042,O15372,Q9Y262,P62701,O00303,P62244,O75821,P62241,P61247,Q04637,O15371,Q14152,P62847,P60866,P08708,P25398,P62266 17
Toll like receptor tlr1 tlr2 cascade 0.2804272032349121 0.1796083117394567 0.8574600789782247 1.0 1.0 13 P09429 1
Cytochrome p450 arranged by substrate type 0.5065561168693677 0.1770991526861407 0.8594305074647726 1.0 1.0 3 P16435 1
Regulation of mrna stability by proteins that bind au rich elements 0.2221676602456234 0.1760091680140028 0.8602867398578131 1.0 1.0 59 O14980,Q9NQT5,O43242,O00487,P62333,Q13200,P39687,P62191,Q9Y2L1,Q15008,Q01105,O75832,Q8IZH2,P51665,Q9NPI6,P35658,P11142,Q04637 18
Recruitment of mitotic centrosome proteins and complexes 0.2583838601084954 0.1741142258691185 0.8617756933383351 1.0 1.0 27 P43034,Q14008,Q14203,Q15154,Q14204 5
Sensory processing of sound 0.256572660620793 0.1734484529113815 0.8622989422914586 1.0 1.0 16 P15311,Q00013,P52907,P35579,Q13813,O00159,P47756 7
Death receptor signalling 0.2536201360175812 0.1729828877301414 0.8626648784600492 1.0 1.0 17 Q9NY61,Q96BN8,Q14344,Q13547,Q92769,Q92974,Q9NQC3,P49327 8
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.2935045725594759 0.1684886736807404 0.8661988533887819 1.0 1.0 11 Q13547,Q92769,O94776,Q14839 4
Formation of the early elongation complex 0.289666037348826 0.1574440687346119 0.8748948846891131 1.0 1.0 11 P19447,P24928 2
Rrna processing in the mitochondrion 0.3506817526638708 0.1564437860860459 0.8756832257354343 1.0 1.0 5 Q7L0Y3 1
Cyclin d associated events in g1 0.3016003993514709 0.152400768812125 0.8788708507367906 1.0 1.0 8 P11802 1
Signaling by cytosolic fgfr1 fusion mutants 0.3044765923937426 0.1519051620668425 0.8792617368061881 1.0 1.0 7 P40763,O15164,Q9UBW7 3
Fgfr1 mutant receptor activation 0.3044765923937426 0.1519051620668425 0.8792617368061881 1.0 1.0 7 P40763,O15164,Q9UBW7 3
Signaling by fgfr1 in disease 0.3044765923937426 0.1519051620668425 0.8792617368061881 1.0 1.0 7 P40763,O15164,Q9UBW7 3
Rmts methylate histone arginines 0.2393973354581217 0.1484939534346615 0.8819529575154879 1.0 1.0 19 O14744,Q86U86,Q99873,Q92922,Q96GM5,P51532,P11802 7
Chaperone mediated autophagy 0.3329277970259517 0.1482146491735971 0.8821733711358799 1.0 1.0 6 P07900,P08238 2
Collagen formation 0.2785240466853561 0.1481427255971812 0.8822301312749294 1.0 1.0 12 Q15149 1
B wich complex positively regulates rrna expression 0.2427265867561206 0.1481044340925066 0.8822603501403263 1.0 1.0 18 O95602,Q3B726,O75533,Q9BQG0,P35659,Q9NR30,O00159 7
Base excision repair ap site formation 0.3458221879477737 0.1454936971653963 0.8843210917355036 1.0 1.0 5 Q15554 1
Recognition and association of dna glycosylase with site containing an affected purine 0.3458221879477737 0.1454936971653963 0.8843210917355036 1.0 1.0 5 Q15554 1
Deadenylation of mrna 0.2914402020532911 0.1428047178327976 0.8864444109821892 1.0 1.0 10 Q04637 1
Termination of translesion dna synthesis 0.267983103040486 0.1422462949732772 0.8868854654434679 1.0 1.0 13 Q07864,P40938,P12004,P28340,P35251,Q9Y2S7 6
Telomere maintenance 0.251198379417505 0.1411570403549494 0.8877458830174141 1.0 1.0 30 P54132,P30876,P40938,P12004,O60832,P28340,P35251,P49643,Q9Y2S7,P24928,P39748,Q15554,P24941,O15514 14
Tcf dependent signaling in response to wnt 0.2268922997878955 0.138030100524463 0.8902166284552295 1.0 1.0 55 Q15291,Q13200,Q9HCK8,Q13618,P62333,Q13547,O75832,P51532,O14980,O43242,P51665,P55036,P49841,O00487,P19784,Q14738,Q15008,Q9Y4A5,Q6P1J9,P62191 20
Trna processing in the nucleus 0.2507751152735467 0.134046645051651 0.8933656898258813 1.0 1.0 35 P78346,Q92499,Q99575,P12270,P49790,Q9Y224,Q9Y3I0,Q9BQ52,P35658 9
Synthesis of dna 0.2200881919201595 0.1318354206819662 0.8951144694091611 1.0 1.0 69 Q07864,Q13200,P39748,P24941,P49736,P12004,P62333,O43913,O75832,P33993,P33991,O43242,P25205,P28340,P35251,P51665,P55036,P40938,P33992,O00487,P49643,P62191,Q15008,Q9Y2S7,Q13416 25
Hiv life cycle 0.2086033994894854 0.1264736448314815 0.8993570098840089 1.0 1.0 62 P30876,O14980,P13010,P30419,P19447,P12270,Q8WUM4,P24928,P39748,Q08945,P46060,Q92804,P35658,Q9UN37,Q9Y5B9 15
Downregulation of tgf beta receptor signaling 0.3363770350533382 0.1254066766738712 0.9002016026239179 1.0 1.0 5 O14980 1
Sensory processing of sound by outer hair cells of the cochlea 0.275399959795108 0.1198618753743597 0.9045925657272342 1.0 1.0 11 Q13813,Q00013,O00159,P35579 4
Transport of connexons to the plasma membrane 0.3333984787511076 0.1194018210079293 0.9049570186616792 1.0 1.0 5 Q9BVA1,P68371 2
Gap junction assembly 0.3333984787511076 0.1194018210079293 0.9049570186616792 1.0 1.0 5 Q9BVA1,P68371 2
Zbp1 dai mediated induction of type i ifns 0.5689935064935037 0.1155296112502998 0.9080253512244444 1.0 1.0 2 Q9NZI8 1
Rip mediated nfkb activation via zbp1 0.5689935064935037 0.1155296112502998 0.9080253512244444 1.0 1.0 2 Q9NZI8 1
Inhibition of dna recombination at telomere 0.2799002657910424 0.1141307149578715 0.9091341742848508 1.0 1.0 10 Q15554,P24928 2
Unfolded protein response upr 0.2440977381645498 0.1130732349319977 0.9099724943104356 1.0 1.0 34 Q9HCU5,Q9Y2L1,P08243,Q9Y4L1,Q14203 5
Transcriptional regulation by runx1 0.204426963243957 0.1123280235183318 0.910563322854324 1.0 1.0 61 Q07157,Q15291,Q13200,Q03164,P62333,Q13547,Q86U86,O75832,Q99873,P51532,O43242,Q96J02,P51665,Q9HCE1,Q06124,O00487,Q96ST3,P19784,P62191,Q15008,Q92922,Q96GM5 22
Apoptotic execution phase 0.2386647111349832 0.1113775978758898 0.9113169238266374 1.0 1.0 27 P26583,Q15149,P15924,P09429 4
Interferon gamma signaling 0.2811446859171288 0.1097001178748853 0.9126472069308308 1.0 1.0 9 P29372,P19474,Q06124,O15344 4
L1cam interactions 0.2418850556119429 0.10583903469773 0.915710065499221 1.0 1.0 35 P19784,Q15334,P36507,Q00610,O95239 5
Neddylation 0.2076040006464104 0.1056192309897384 0.9158844659737282 1.0 1.0 64 Q15291,Q13200,Q13618,P62333,Q8N668,O75832,Q9UNS2,O43242,P61962,P51665,P55036,Q9BT78,O00487,Q86VP6,Q93034,P62191,Q15008,Q13620,P25787,P61201 20
G2 m checkpoints 0.2217771179297161 0.1031256606101665 0.9178632393745334 1.0 1.0 74 P54132,Q92547,O60934,P33992,P25205,Q13200,P33993,P33991,Q14676,P51665,Q13416,P49736 12
Sumoylation 0.2094534840656034 0.1001479964230032 0.9202268312015522 1.0 1.0 66 P54132,P12004,Q14683,Q96ST3,Q13547,Q92769,P49792,P12270,P49790,P09874,P46060,P26358,Q9UQE7,P35658,Q14676,Q13330 16
Interferon signaling 0.2158718152089259 0.0989625425583039 0.9211680107731332 1.0 1.0 56 O43432,O75369,O00629,Q06124,P29372,P19474,P49792,P12270,P21333,P49790,Q04637,Q6L8Q7,P35658,P78344 14
Translesion synthesis by polk 0.2820369447577961 0.0988855393786357 0.9212291505324316 1.0 1.0 7 P35251,P12004 2
Cyclin a b1 b2 associated events during g2 m transition 0.2817167560779535 0.0982131232496095 0.9217630619987712 1.0 1.0 7 P24941 1
Trna processing 0.2338103400310909 0.0976305011241028 0.9222257038029936 1.0 1.0 46 P78346,P07814,Q99575,P12270,P49790,Q7L0Y3,Q9Y224,Q9Y3I0,Q92499,P35658,Q08J23 11
Signaling by fgfr in disease 0.238104491533501 0.0896121873452895 0.928595399273762 1.0 1.0 14 P30876,O15164,P40763,P24928,Q9UBW7,O15514 6
Copi mediated anterograde transport 0.2252768198959803 0.0876165231044373 0.930181469146941 1.0 1.0 50 P53621,P24390,P35606,Q92538,Q14203,P62820,Q14204 7
Rhoc gtpase cycle 0.2266318812594987 0.0849072793516081 0.9323351046029806 1.0 1.0 26 P49257,Q16513 2
Synthesis of udp n acetyl glucosamine 0.5413961038961007 0.084882338565034 0.9323549328901176 1.0 1.0 2 Q16222 1
Cell junction organization 0.2265126913247475 0.084395983800473 0.9327416003587978 1.0 1.0 15 P21333,Q15149,Q9BY67,P55196 4
Glycogen synthesis 0.4425497360942023 0.0836208233955407 0.9333579102447194 1.0 1.0 3 Q96G03,Q16851 2
Signaling by fgfr2 iiia tm 0.2732915278112796 0.0813698670609363 0.935147812227622 1.0 1.0 7 P24928 1
Fgfr2 mutant receptor activation 0.2732915278112796 0.0813698670609363 0.935147812227622 1.0 1.0 7 P24928 1
Rho gtpases activate iqgaps 0.2634364820846904 0.0790668684260731 0.9369794361499336 1.0 1.0 10 P04350,Q13885,P63000,P35221,P46940,Q9BUF5,P68371,P60953,Q9BVA1 9
Rrna processing 0.3131974371670289 0.0783206602658074 0.937572983425554 1.0 1.0 152 P83881,P27635,Q9Y2R4,P46087,P61313,Q8IY37,P18621,Q9BQ52,P08708,P62910,P62266,P42766,Q2NL82,P62241,P50914,O15213,P40429,P18077,Q02878,Q7L0Y3,Q92979,P60866,P56182,Q9Y3U8,Q9NQT5,Q14137,P39023,P62917,Q07020,Q8IY81,Q68CQ4,Q02543,P78346,Q14692,Q13895,P36578,P62701,Q9Y2L1,O75691,P62899,Q14690 41
Copi independent golgi to er retrograde traffic 0.2241386547325776 0.0740711190594794 0.9409537957663716 1.0 1.0 28 P68402,Q15042,P43034,P68371,Q8TD16,Q96FJ2,Q14203,Q9BVA1,Q9Y6G9,Q14204 10
Asparagine n linked glycosylation 0.2453992544944689 0.0740513314933311 0.9409695407195836 1.0 1.0 96 Q8NFW8,Q9HCU5,P53621,P49257,Q15436,Q9H0U3,P24390,Q9NR45,P35606,Q92538,Q14203,P62820,Q14204 13
Rna polymerase iii transcription initiation from type 1 promoter 0.2664791503898369 0.0737791859947934 0.9411860890496124 1.0 1.0 8 Q12789 1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0.3319467396259343 0.0725562145452289 0.942159270567846 1.0 1.0 4 A5YKK6 1
G2 m dna damage checkpoint 0.2207656648026843 0.0699751861714838 0.9442134097796496 1.0 1.0 27 O60934,Q92547,Q14676 3
Dna replication pre initiation 0.2056656017585465 0.0684221724872703 0.9454495720960112 1.0 1.0 57 Q07864,O43242,P33992,P25205,O00487,P62333,P49643,Q13200,P62191,Q15008,O43913,P33993,P33991,P51665,P24941,Q13416,P49736 17
Diseases of signal transduction by growth factor receptors and second messengers 0.2795906646517476 0.0664168056582387 0.9470459907640318 1.0 1.0 125 Q7Z2W4,P26641,O15164,Q9P2E9,Q13200,P24928,P46940,Q14203,P62333,Q13547,P40763,Q9NR09,O00203,P22681,O75832,P36507,Q9HC35,Q9BZK7,Q86WB0,Q7KZF4,O43242,P10644,Q92769,P49792,P33176,Q9UBW7,P21359,P28482,Q6WCQ1,Q00610,P51665,P35579,P55036,P07900,Q9UBV2,P31939,P30876,P49841,O00487,Q06124,P42345,P62191,Q14738,Q15008,Q9NWH9,P12270,P18206,P25787,O15514 49
Recruitment of numa to mitotic centrosomes 0.2220377343657098 0.0633610934984038 0.9494789678612854 1.0 1.0 31 P43034,Q14008,Q14203,Q15154,Q14204 5
Phase ii conjugation of compounds 0.2028704679329008 0.0581236301115145 0.9536501521017352 1.0 1.0 21 O60701,Q9NUJ1,P48506,Q8TB61,Q9NZL9,P10768 6
Sumoylation of dna damage response and repair proteins 0.2226988785824595 0.0567721054519402 0.9547267347128928 1.0 1.0 38 P54132,Q14683,P12270,P49790,P09874,Q9UQE7,P35658,Q14676 8
Apoptotic cleavage of cellular proteins 0.2085391040044498 0.0565459017026366 0.9549069297245624 1.0 1.0 16 Q13813,Q07157,Q15149,P15924 4
Chromosome maintenance 0.219490398309735 0.0538984632838625 0.957016061009832 1.0 1.0 34 P54132,P30876,P40938,P12004,O60832,P28340,P35251,P49643,Q9Y2S7,P24928,P39748,Q15554,P24941,O15514 14
Nervous system development 0.3410033320598553 0.052744194511421 0.9579357258826022 1.0 1.0 190 P27635,O15143,Q14185,Q13200,P61313,P18621,P08708,P62910,P62266,O15020,P18077,Q02878,Q15334,P36507,P60866,P51532,P35580,Q9Y3U8,Q9BZI7,P15170,O75122,Q92769,P62917,Q00610,P51665,P35579,P07900,Q02543,P46939,P36578,P19784,Q9NWH9,P62899,O95239,Q04637 35
Tbc rabgaps 0.2315982292438311 0.0485095687497148 0.9613101386615828 1.0 1.0 12 Q8TC07 1
Signaling by insulin receptor 0.2236709478540906 0.0483689183967266 0.9614222298263122 1.0 1.0 13 P28482,Q99570,P38606 3
Endogenous sterols 0.4906655844155806 0.0464615412256111 0.9629423866204913 1.0 1.0 2 Q16850 1
Antiviral mechanism by ifn stimulated genes 0.2149839606013393 0.0453126351136259 0.9638581164193476 1.0 1.0 46 O43432,O75369,O00629,P12270,P21333,P49790,Q6L8Q7,P35658,Q04637,P78344 10
Fceri mediated mapk activation 0.2840308817553872 0.0426387108891499 0.9659895367097188 1.0 1.0 5 P62993,P28482,P27361,P63000 4
Keratinization 0.2838705456547025 0.0424566791636211 0.9661346456076524 1.0 1.0 5 P07384,P15924 2
Formation of the cornified envelope 0.2838705456547025 0.0424566791636211 0.9661346456076524 1.0 1.0 5 P07384,P15924 2
Polo like kinase mediated events 0.4825487012986974 0.0421735633900182 0.9663603371628936 1.0 1.0 2 Q09028 1
Plasma lipoprotein assembly 0.4797077922077883 0.0407780400871163 0.9674728462661684 1.0 1.0 2 P07237 1
Signaling by fgfr2 in disease 0.2412247896886962 0.035005398387343 0.9720754362223832 1.0 1.0 8 P24928 1
Cd28 co stimulation 0.2767167817960226 0.0347456751858267 0.9722825393659732 1.0 1.0 5 P42345,P62993,Q13177,P63000 4
Trafficking and processing of endosomal tlr 0.4634740259740221 0.0337763833902089 0.9730554685220932 1.0 1.0 2 P14625 1
Rho gtpases activate ktn1 0.2412337763322377 0.0318154747229672 0.9746192058394728 1.0 1.0 7 Q86UP2 1
Caspase mediated cleavage of cytoskeletal proteins 0.2625132995561539 0.031207424126 0.9751041192031766 1.0 1.0 6 Q15149 1
Inositol phosphate metabolism 0.356069833536344 0.0241570785279356 0.9807273145023492 1.0 1.0 3 Q9NPH2,Q9UNW1 2
Switching of origins to a post replicative state 0.195384219404762 0.0229134834463615 0.9817192849849636 1.0 1.0 54 O43242,P33992,P25205,O00487,P62333,Q13200,P62191,Q15008,O43913,O75832,P33993,P33991,P51665,P24941,Q13416,P49736 16
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0.3451075923670353 0.0206657304720346 0.9835123063001996 1.0 1.0 3 P10809,P46087 2
Mhc class ii antigen presentation 0.1987758905822055 0.018860703463329 0.9849522280536436 1.0 1.0 49 Q14807,O15020,Q15436,P33176,Q96FJ2,Q00610,O95239,Q14203,Q9BVA1,Q9Y6G9,Q14204 11
Cobalamin cbl vitamin b12 transport and metabolism 0.337861609115776 0.018710681682379 0.9850719069969884 1.0 1.0 3 P33527 1
P75 ntr receptor mediated signalling 0.1875292257812993 0.0184120837873841 0.985310112608988 1.0 1.0 14 Q9NQC3,Q13547,Q92769 3
Bmal1 clock npas2 activates circadian gene expression 0.3365814047909118 0.0183921847227424 0.9853259870773587 1.0 1.0 3 P43490,Q9BZK7 2
Interleukin 12 family signaling 0.1745792452402669 0.0182071143861809 0.9854736271186436 1.0 1.0 27 P40763,P14174,O14979 3
Fceri mediated ca 2 mobilization 0.377435064935061 0.0163972177879391 0.986917499335444 1.0 1.0 2 P62993 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.377435064935061 0.0163972177879391 0.986917499335444 1.0 1.0 2 P62993 1
Sumoylation of transcription factors 0.3244011368250138 0.015731125700826 0.987448895348185 1.0 1.0 3 Q12888,Q13330 2
Synthesis of ip2 ip and ins in the cytosol 0.3559253246753207 0.0151009234806595 0.9879516642155016 1.0 1.0 2 Q9NPH2 1
Telomere extension by telomerase 0.2195791458125894 0.0148086473329654 0.9881848407644944 1.0 1.0 9 O60832,Q15554,Q9NX24,P24941,Q9NYB0 5
Dap12 signaling 0.3222402597402561 0.0140954970345029 0.9887537929456554 1.0 1.0 2 P62993 1
Mapk family signaling cascades 0.2036609309880969 0.0138936199951264 0.9889148517460136 1.0 1.0 80 Q13200,P46940,P25685,Q13618,O15020,Q15334,P36507,Q13813,O14980,O43242,O60725,P21359,P28482,P51665,Q9HCE1,Q06124,O00487,P62191,Q14738,Q9NWH9,P18206 21
Constitutive signaling by akt1 e17k in cancer 0.3065237786151223 0.0128699913008351 0.989731516117102 1.0 1.0 3 P42345 1
Gene silencing by rna 0.1933438948888392 0.0120961027464296 0.9903489417235398 1.0 1.0 41 P30876,Q9UPY3,O15397,P12270,P49790,P24928,Q9HAV4,P07900,Q9BQ52,P35658 10
Interleukin 1 family signaling 0.1940895155225032 0.0116039606604483 0.9907415867224918 1.0 1.0 43 O43242,Q06124,O00487,P09429,P62333,Q13200,P40763,P62191,Q15008,O75832,P51665,P55036 12
Transcriptional regulation of white adipocyte differentiation 0.2202222578497374 0.0107101249538585 0.9914547200222792 1.0 1.0 7 P11802 1
Regulation of ras by gaps 0.1876976724305349 0.0102536469572657 0.99181891675726 1.0 1.0 38 O43242,O00487,P62333,Q13200,P62191,Q15008,P21359,O75832,P51665,P55036,Q13618 11
Protein folding 0.1711829352081189 0.0091998616955438 0.9926596759361416 1.0 1.0 32 Q15477,P04350,Q9Y2T2,Q9BTW9,P40227,Q99426,P40763,O15212,P48643,Q99832,P49368,P17987,P68371,P50991,P61962,P19784,P78371,Q9BVA1 18
Signaling by hippo 0.2416807288971695 0.0075165216297915 0.9940027399129991 1.0 1.0 5 Q07157 1
Sars cov infections 0.1887810617108581 0.0074699069010757 0.9940399320411928 1.0 1.0 52 Q96SB4,Q13547,Q9H0U3,Q92769,Q14839,Q13618,Q99570 7
Signaling by hedgehog 0.1841401463262008 0.0053671575885211 0.9957176483845748 1.0 1.0 55 O43242,P49841,O00487,P62333,Q96J02,Q13200,P10644,P62191,Q6P1J9,Q15008,Q9BVA1,P68371,O75832,P51665,P55036,Q13618,Q9UBV2 17
Synthesis of bile acids and bile salts 0.2411183155938847 0.0049925212072499 0.9960165609573088 1.0 1.0 4 P51659 1
Bile acid and bile salt metabolism 0.2411183155938847 0.0049925212072499 0.9960165609573088 1.0 1.0 4 P51659 1
N glycan trimming in the er and calnexin calreticulin cycle 0.1702888621521226 0.0032154407229021 0.9974344539119092 1.0 1.0 13 P55072,P62191,P54727,Q14697,Q9BUN8,Q9UBV2 6