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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Notch1 regulation of endothelial cell calcification 0.9340740740740756 3.225858949866747 0.0012559523619133 0.5211896334467233 0.0126894497255382 2 Q9H2H9 1
Thermogenesis 0.7206591995101578 3.209480427573173 0.0013297509954857 0.5414805818694141 0.0132073573449936 25 P51812,Q15418,O43772 3
Drug induction of bile acid pathway 0.9018518518518532 3.0832359775996996 0.002047627151535 0.6991488557733754 0.0171415644399934 2 P08183 1
Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway 0.8622222222222262 2.9043706154139644 0.0036799226663113 0.884722406164759 0.0272966415501069 2 P09601 1
Mitochondrial long chain fatty acid betaoxidation 0.7678053398533714 2.7012270438455643 0.0069084160412602 0.9827919902385016 0.045486874159309 14 P23786,Q9BY49,O43772 3
Fatty acid betaoxidation 0.6815070151416012 2.611880540481568 0.0090045712197321 0.9950112975581072 0.0561348801570538 18 P23786,O43772,P43304 3
Degradation pathway of sphingolipids including diseases 0.908987559895312 2.3964090947811862 0.0165565998123844 0.9999436192416168 0.0941958008743425 6 P16278,P06280,P17900 3
Cholesterol metabolism with bloch and kandutschrussell pathways 0.6132219064477493 2.3796418724453474 0.0173294707615661 0.9999644329466332 0.0958935915486018 21 Q16850,P48449,P37268,Q9BWD1 4
Mitochondrial complex iv assembly 0.7602121782980492 2.336855691736006 0.0194466888942252 0.9999899508489272 0.1055162934445928 10 P00403,P14406 2
Glycosaminoglycan degradation 0.8762349733886852 2.263514125900021 0.0236040148294627 0.9999991666504644 0.1257450244551378 6 P16278,P54802,P06865 3
Cholesterol biosynthesis pathway 0.7120019185438373 2.167740727261487 0.0301784188649971 0.9999999840991388 0.1392484524006956 11 Q16850,P48449 2
Hostpathogen interaction of human coronaviruses mapk signaling 0.8193546590658306 2.1298352043281996 0.0331852211311682 0.9999999974227156 0.148446867044768 7 Q15418 1
Nephrotic syndrome 0.7252355808020142 2.1022685485822357 0.0355297580356519 0.9999999993787652 0.1553764045439704 9 Q14108,O75844 2
Metapathway biotransformation phase i and ii 0.5679790306644139 2.078845009472428 0.0376315984175408 0.9999999998270048 0.1586483213861793 21 Q8NEC7,P21964,P07099,Q9H2H9,Q16850,P00390 6
Statin inhibition of cholesterol production 0.8695488234449693 2.063454885430174 0.0390694299058897 0.9999999999279692 0.1605115912324835 3 P37268 1
Influence of laminopathies on wnt signaling 0.7959400116711288 2.0289182849760112 0.0424666140308545 0.9999999999909592 0.1728155265422273 7 P50402,O60725,O75844 3
Ferroptosis 0.5517339557149352 2.0178813002754348 0.043603625009047 0.9999999999954936 0.1750118099678188 23 Q6P1A2,P09601,Q9H2H9,P37268,P45880,Q9Y277,P02786 7
Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8435059926696042 2.0045276786922064 0.0450135650076286 0.9999999999981016 0.1794418305746285 5 P09601,O15439,P07099 3
Sarscov2 and covid19 pathway 0.8533581647868443 1.9992160652030992 0.0455849810778126 0.9999999999986632 0.1804918845378256 3 Q8WTV0 1
Tyrobp causal network in microglia 0.8086980583675736 1.983126219989673 0.0473533324922965 0.9999999999995492 0.1849936856032386 6 Q15418,P61916 2
Vitamin dsensitive calcium signaling in depression 0.78977113095651 1.903053631341063 0.0570335474965155 0.9999999999999988 0.2142414027753725 6 Q8NB78 1
Familial partial lipodystrophy fpld 0.7887576259247051 1.8987480814754183 0.0575976064474381 0.9999999999999992 0.2149821489057246 6 O60725,Q03252,P02545,O75844 4
Complement system in neuronal development and plasticity 0.7166239676929305 1.8595038715295973 0.0629557510018417 1.0 0.2320255980319449 8 Q5KU26,Q8NB49,Q9NR28 3
Electron transport chain oxphos system in mitochondria 0.4485767260916124 1.8495605505195247 0.0643769130855491 1.0 0.2352944267454962 47 Q16718,P00403,O75964,P06576,P13073,O95139,P56134,O75489,O96000,O75880,P14406,P56385,P22695,Q7KZN9,P24539,O43676 16
Cytosine methylation 0.7996914583974332 1.8254280123535371 0.0679364652970559 1.0 0.2442378445648761 5 P48735 1
Acquired partial lipodystrophy barraquersimons syndrome 0.8128243143069036 1.81276041634074 0.0698687816065719 1.0 0.2481400364936433 4 O60725,Q03252,P02545 3
Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.7980733605038948 1.77690547748287 0.0755837930280485 1.0 0.2620834480144167 3 P06753,P18031 2
Ppar signaling pathway 0.5829192249677831 1.760340756317681 0.0783500477362895 1.0 0.2669367905434049 15 O15254,P23786,P11310 3
Primary focal segmental glomerulosclerosis fsgs 0.5580613439942159 1.6923215554143225 0.0905846800822469 1.0 0.3068359683710793 16 Q14108 1
Kit receptor signaling pathway 0.56681074493333 1.6640296131325178 0.0961065116558979 1.0 0.3215375689009284 15 Q15418 1
Urea cycle and related diseases 0.6074074074074103 1.65898056139513 0.0971197093779254 1.0 0.3215375689009284 2 Q9UJS0 1
7oxoc and 7betahc pathways 0.7105134126541934 1.6518934355579105 0.0985562765188396 1.0 0.3226479220113969 7 O15118 1
Cholesterol biosynthesis with skeletal dysplasias 0.7552048118797277 1.6406263318165153 0.1008750055346683 1.0 0.323020509526315 5 Q15392,Q16850 2
Oxidation by cytochrome p450 0.7529480159377882 1.6311799621243903 0.1028523521139459 1.0 0.3250145322425828 5 Q16850 1
Vitamin d metabolism 0.7606520933679166 1.624079961626774 0.1043587440105622 1.0 0.3250145322425828 3 P38435,P04062 2
Type i collagen synthesis in the context of osteogenesis imperfecta 0.6074650437791282 1.6220969581617457 0.1047825893896294 1.0 0.3250145322425828 11 Q32P28,P13674,Q96AY3,O75718,Q5JRA6,O15460 6
Egfegfr signaling pathway 0.4358527102885514 1.611467570786156 0.1070778499226188 1.0 0.3285215709667781 37 P16949,P00403,Q15418,P51812 4
Overlap between signal transduction pathways contributing to lmna laminopathies 0.589096571532394 1.583124195002388 0.1133931599468482 1.0 0.3394010083610558 12 P55209,O75844,P50402,O60725,Q9Y2U8 5
Mevalonate arm of cholesterol biosynthesis pathway 0.6559844735739702 1.5723710332651073 0.1158645280421919 1.0 0.342912189054164 8 P37268 1
Vitamin a and carotenoid metabolism 0.7376775764488879 1.5670992808385102 0.117091487283619 1.0 0.3430951083524634 5 O94788 1
Striated muscle contraction pathway 0.7367472601136349 1.563186533084861 0.1180087267405496 1.0 0.3440453426366273 5 P08670,P09493 2
Ketogenesis and ketolysis 0.7028528801688727 1.420036760570568 0.1555969792914648 1.0 0.4144537721127201 5 P23786,O43772 2
Ectoderm differentiation 0.490866340405938 1.401473301615386 0.1610725858817665 1.0 0.4213773898514071 18 P16278,O00560,O15439,Q9UPN9,Q9H6U6 5
Alzheimers disease 0.3584649000020802 1.3921532619151988 0.1638759924407729 1.0 0.4250669497949535 74 P28070,P49721,P28074,P07437,Q14790,P04350,Q99436,P45880,O95197,Q9BVA1,P68371,Q13885,P21796 13
Cellular proteostasis 0.708723840672246 1.386206648804886 0.1656838118550827 1.0 0.4253883865803934 4 O15212,Q99471 2
Arrhythmogenic right ventricular cardiomyopathy 0.5497598114458417 1.3641505713023374 0.1725201811920265 1.0 0.4302768241525239 12 P02545,P14923,P16615,P50402,P15924,P35221,P05556 7
Genes related to primary cilium development based on crispr 0.6120766774208274 1.3605967704183954 0.1736411527710943 1.0 0.4302768241525239 8 Q7Z4L5 1
Endothelin pathways 0.6409214373614294 1.336286580525773 0.1814556210251205 1.0 0.4412157424096293 7 P00403 1
Phase i biotransformations non p450 0.6888842010602187 1.32715817654873 0.1844563641149446 1.0 0.4466587990551964 3 P38571 1
Eicosanoid metabolism via lipooxygenases lox 0.6359958617920588 1.3137575458744069 0.1889278085698655 1.0 0.4537364582866444 7 O15254,Q8N8N7 2
Amino acid metabolism pathway excerpt histidine catabolism extension 0.540370370370376 1.3081652974327636 0.1908172497079532 1.0 0.4564037074647371 2 Q8TD30 1
Alzheimers disease and mirna effects 0.3497462911693936 1.302744339808538 0.1926620588962679 1.0 0.4580156863931106 75 P28070,P49721,P28074,P07437,Q14790,P04350,Q99436,P45880,O95197,Q9BVA1,P68371,Q13885,P21796 13
Nanomaterial induced apoptosis 0.6438154626587311 1.267671019012312 0.2049154584178145 1.0 0.468351125098109 6 Q9NR28,O95831 2
Sterol regulatory elementbinding proteins srebp signaling 0.4318837978895928 1.267264222448256 0.205060828791149 1.0 0.468351125098109 28 Q16850,Q8WTV0,P48449,P37268 4
Glutathione metabolism 0.6404587896918388 1.2528130290588917 0.2102737588581282 1.0 0.4698624469040363 6 O75874,P00390 2
Microrna network associated with chronic lymphocytic leukemia 0.5229629629629691 1.2166105530745244 0.2237524256389043 1.0 0.4876323349476084 2 Q07820 1
Tryptophan metabolism 0.5019571063041219 1.2049365236680325 0.2282278074923396 1.0 0.4916966734945258 14 O94788 1
22q112 copy number variation syndrome 0.4189761195087989 1.1950193469897796 0.2320794712481246 1.0 0.4978230045319345 29 O94788,P21964 2
Ciliopathies 0.4761440918003099 1.1758238376911965 0.2396652786446416 1.0 0.4982934636151448 16 O43924,Q7Z4L5,Q13432 3
Angiopoietinlike protein 8 regulatory pathway 0.4375751952776125 1.1733800585858307 0.2406434303806928 1.0 0.4982934636151448 22 Q15418,P51812 2
Eicosanoid metabolism via cyclooxygenases cox 0.601996181198338 1.1579614439028223 0.2468797710316841 1.0 0.504121184599056 7 O15254,Q8N8N7 2
Pparalpha pathway 0.6014447978626789 1.155433544744159 0.2479129317647666 1.0 0.504121184599056 7 P23786 1
Progeriaassociated lipodystrophy 0.5376081297813555 1.1529514809843464 0.2489302997946678 1.0 0.504121184599056 9 O60725,Q03252,P02545,O75844 4
Ethanol effects on histone modifications 0.5356839943372426 1.1429536979051875 0.253057815795412 1.0 0.504121184599056 9 O94788 1
Dna mismatch repair 0.4909709893469806 1.139148030015546 0.2546414174766562 1.0 0.504121184599056 14 Q9UQ84 1
Pathogenic escherichia coli infection 0.4385697487006554 1.0981949970427194 0.2721193503768342 1.0 0.520390502881097 19 P07437,P04350,Q9BVA1,P68371,Q13885 5
Adipogenesis 0.4931708495182663 1.096702836257382 0.2727713162011884 1.0 0.520390502881097 13 P17096,P14174,O75844,P43490 4
Allograft rejection 0.5245736563090599 1.0852342602904503 0.2778179138014183 1.0 0.5218088023184635 9 Q9BY49,P08670,P08183,Q14790 4
Development of ureteric collection system 0.6306731966012724 1.085222510364295 0.2778231165927656 1.0 0.5218088023184635 3 P05556 1
Endoplasmic reticulum stress response in coronavirus infection 0.522244093443901 1.073137250813001 0.2832095396179179 1.0 0.523535615823659 9 Q96C90 1
Transcriptional activation by nrf2 in response to phytochemicals 0.6261540440170227 1.066515242131735 0.2861907922624258 1.0 0.5257297939366192 3 P09601 1
Omega3 omega6 fatty acid synthesis 0.5909797293996314 1.0339296036275356 0.3011690742935573 1.0 0.533280725159957 6 O15254 1
Lung fibrosis 0.5883251535265349 1.0222266607304142 0.3066736351168471 1.0 0.5366360295835028 6 P09601,Q86TI2 2
Nicotine effect on dopaminergic neurons 0.4818518518518547 1.001494585852289 0.3165877563306714 1.0 0.5481736360971143 2 P17612 1
Cardiac progenitor differentiation 0.4774074074074158 0.9784437959485028 0.3278548762629596 1.0 0.5568781376524473 2 Q6ZN17 1
Apoptosis modulation by hsp70 0.5905091630589604 0.943161540382691 0.345598281984949 1.0 0.5769817471315672 5 O95831 1
Interactions between loxl4 and oxidative stress pathway 0.4629629629629643 0.9039807927490512 0.366005586197196 1.0 0.589228773383398 2 Q16543 1
Nonalcoholic fatty liver disease 0.3540648970345496 0.8990356022206368 0.3686336974550726 1.0 0.5918338265991028 44 P22695,P00403,P14406,O43676 4
Vitamin d receptor pathway 0.4796365839360511 0.8871046836202778 0.3750225426985059 1.0 0.5997962175125925 10 P08183 1
Mitochondrial complex iii assembly 0.5423716256163588 0.8859577527395579 0.3756402932203437 1.0 0.5997962175125925 7 P22695 1
Pregnane x receptor pathway 0.5705403048351262 0.8596279969794883 0.3899941369452091 1.0 0.611060332218964 5 P08183 1
Riboflavin and coq disorders 0.5681554267131188 0.8294253388240329 0.4068637682228302 1.0 0.6229938126877392 3 Q16134 1
Metabolism of spingolipids in er and golgi apparatus 0.5671269354363977 0.8028647532606281 0.4220529102954331 1.0 0.6305212244285393 4 Q06136,O95470 2
Folate metabolism 0.4334692797585466 0.7959071327404142 0.4260860151428354 1.0 0.6305212244285393 14 Q8WTV0 1
Oxidative stress response 0.5383345882101698 0.7272562890823204 0.4670689696854593 1.0 0.6791623231654569 5 P09601 1
Apoptosis modulation and signaling 0.4318607162971818 0.7033817950008674 0.4818178486841469 1.0 0.6920226944336031 12 Q9NR28,O95831 2
Insulin signaling 0.3480439428790387 0.6922921324974489 0.4887538898386254 1.0 0.6934861487782917 33 Q15418,P51812 2
Genes controlling nephrogenesis 0.5328377512429631 0.6677467492763874 0.5042952631381441 1.0 0.7023696027036581 4 P05556 1
Methionine de novo and salvage pathway 0.4881760316628013 0.6459648506356224 0.518302119142318 1.0 0.7121068387286514 7 Q13126 1
Nrf2are regulation 0.5175492564865072 0.6440172102756565 0.5195642739288984 1.0 0.7121068387286514 5 P09601,P48507 2
S1p receptor signal transduction 0.484691513814532 0.6309835849019836 0.5280512575628329 1.0 0.7179536819763808 7 Q9H0H5 1
Amyotrophic lateral sclerosis als 0.4339743227772088 0.6235442618021767 0.5329269254492801 1.0 0.7188957901495491 9 Q9BUN8,P07196 2
Ccl18 signaling pathway 0.4252844814349378 0.5812284607545797 0.5610864884081481 1.0 0.743883896396323 9 P08670,P00403 2
Onecarbon metabolism and related pathways 0.4030202942882963 0.5200937930257962 0.6029982043537063 1.0 0.7718817785645655 11 P34896,P35790,P48507,O43865,P34897,P00390 6
Selenium micronutrient network 0.4027515664503898 0.5187406642423692 0.603941600485161 1.0 0.7718817785645655 11 Q8WTV0 1
Mrna protein and metabolite inducation pathway by cyclosporin a 0.3833333333333339 0.5170633150515787 0.6051119612072662 1.0 0.7718817785645655 2 P08195 1
Burn wound healing 0.407952627178735 0.4986948692642313 0.6179943596621988 1.0 0.7777508860898904 9 O60885,P08670,Q99439 3
Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.4568273734682955 0.4697795065697682 0.6385125574014208 1.0 0.7978003382456984 6 P35221,P05556 2
Oxidative phosphorylation 0.3286471421487868 0.4610385482387892 0.6447709489096303 1.0 0.7988071375497745 29 Q16718,O75964,P06576,Q15904,O95139,P56134,O96000,P56385,P24539 9
Hippoyap signaling pathway 0.3685185185185158 0.4523824902778727 0.650993458804912 1.0 0.8018745592331843 2 Q13043 1
Mthfr deficiency 0.4505291552728921 0.4458719816078597 0.6556897222946203 1.0 0.8025262831325466 6 P21964,P35790 2
Brainderived neurotrophic factor bdnf signaling pathway 0.3096809595345076 0.4454564656413563 0.6559899140281396 1.0 0.8025262831325466 37 Q15418 1
Dna replication 0.3336801094977849 0.4179326844163474 0.6759963348844167 1.0 0.813416534378374 21 Q14566 1
Preimplantation embryo 0.4296581393174891 0.4061239176994884 0.6846515527520296 1.0 0.8158165352793554 7 P17096,Q99729 2
Sudden infant death syndrome sids susceptibility pathways 0.3292176949539282 0.3993656648907379 0.6896237893863684 1.0 0.8180557501627771 24 P61981,P62258,P14625,P11310,P42892,Q01082,P67809 7
Histone modifications 0.3790230150812971 0.3680093462196557 0.7128662652237541 1.0 0.8371535699822041 9 Q01105,Q9H7B4 2
Glycerophospholipid biosynthetic pathway 0.4261538235522613 0.357094869967337 0.7210207848206855 1.0 0.8450363598098434 6 Q9BTU6,O95674 2
Parkinubiquitin proteasomal system pathway 0.2962385962675564 0.308565303423175 0.7576522175352536 1.0 0.8599803188211645 36 P07437,O00231,P04350,Q9BVA1,P68371,Q13885 6
Mammary gland development pathway embryonic development stage 1 of 4 0.3311111111111079 0.305234732887115 0.7601873808009612 1.0 0.8599803188211645 2 P05556 1
Novel intracellular components of rigilike receptor rlr pathway 0.396428536087538 0.2851889356966768 0.7754993965815813 1.0 0.8722507608384005 7 Q14790 1
Gdnfret signaling axis 0.40163023341978 0.2489244032551486 0.8034192582541952 1.0 0.8937015138510436 3 O94813,P35222 2
Sphingolipid metabolism in senescence 0.3482780087377285 0.2421246144398844 0.8086836059835258 1.0 0.8941294209553701 9 Q13510 1
Nocgmppkg mediated neuroprotection 0.3974078380249852 0.2286516233468423 0.819139697632296 1.0 0.8978963452485258 5 P07196 1
Joubert syndrome 0.3292959541406635 0.2110441476669558 0.8328528222310057 1.0 0.9054763521843586 13 Q13432 1
Myometrial relaxation and contraction pathways 0.3023496312521488 0.1808878658217039 0.8564555934094549 1.0 0.9225790031947436 18 P61981,Q05682,P10644,P13861,P62258,P63218,P16615,Q99439,P63104,P78417,P31946,Q04917 12
Mitochondrial complex i assembly model oxphos system 0.2950518793153879 0.1729818823779587 0.8626656687029632 1.0 0.927563452954012 23 Q16718,Q9P0J0,Q9H845,O95139,O96000,Q7L592,O43676 7
Proximal tubule transport 0.3096827362484662 0.1204122824908544 0.9041565621742942 1.0 0.9581116553962684 12 O15439,P08183 2
Kennedy pathway from sphingolipids 0.3477483256317905 0.1093033068538166 0.9129619238225528 1.0 0.9604325265546853 4 P35790 1
3q29 copy number variation syndrome 0.3317254174396935 0.0975412429714939 0.9222965832077292 1.0 0.9637432870756836 7 Q09161,Q13177,O75592,Q8NCM8,P61088,P02786 6
Hedgehog signaling pathway wp4249 0.3395107487027385 0.0950028989338195 0.924312524321411 1.0 0.9637432870756836 4 P17612,Q9Y496,P48729 3
Pilocytic astrocytoma 0.3271582067432349 0.0940844639240116 0.9250420616260656 1.0 0.9637432870756836 3 P21359,P62993 2
Smc1smc3 role in dna damage cornelia de lange syndrome 0.3269016697588008 0.0865565318880032 0.9310240186939028 1.0 0.9647197797748102 7 Q92878,Q9UQE7,O60934,O60216,Q14683,P49959 6
Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3314794215795359 0.0795198335050647 0.9366191567089496 1.0 0.9663007497032474 5 Q96B36,Q15118,P05556,P42345 4
Ebola virus infection in host 0.2674697784226399 0.0720922936581242 0.9425284590389068 1.0 0.9706883602755704 35 O15118,P41440 2
Male infertility 0.2709332134153082 0.0455404302041449 0.9636765496685056 1.0 0.9866818916372122 21 P17096,P41440,P08183 3
Hair follicle development organogenesis part 2 of 3 0.2849203408669835 0.0441397042302344 0.9647930442118132 1.0 0.9866818916372122 3 P05556,P35222 2
Proteasome degradation 0.2592380342980971 0.0406807917226213 0.9675503749024972 1.0 0.9877779088725842 40 P28070,P49721,P28074,O00231 4
Cytosolic dnasensing pathway 0.28804751299183 0.0267976260356079 0.9786211466885352 1.0 0.9973425947121418 8 Q14258,P55265,P19388,O14802,Q9NZI8,Q14790,P62875 7
Nipbl role in dna damage cornelia de lange syndrome 0.2586248486947191 0.0076953552406288 0.9938600554633784 1.0 1.0 4 P16104 1