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Sphingolipid metabolism 0.7478723459454395 3.3876699408270996 0.0007048903400694 0.6164494115383049 0.4789729860772165 24 P51648,A0FGR8,P16278,P04062,P10619,P06280,O95470,Q96G23,P07602,P17900,Q13510,P06865,Q06136 13
Slc mediated transmembrane transport 0.7097069785297524 3.0756695558459626 0.0021003047220868 0.942577311614106 0.5286366263530318 22 Q8NEW0,P11166,Q70HW3,Q9H2H9,P04920,O00400,P35613,Q9UBX3,P12236,P53985,Q8TB61,Q96QD8 12
Glycerophospholipid biosynthesis 0.6455428644966617 2.853141872984268 0.0043289290388319 0.9972489840750977 0.7353768204715818 27 Q9NPH0,Q8NF37,Q9NQZ5,Q6P1A2,Q8IV08,P35790,P48651 7
Ion channel transport 0.6237717307936962 2.7029045107951792 0.0068736490009611 0.9999150579451774 0.8492080902096488 27 Q96PU5,Q9Y487,Q93050,P16615,P05023,P98194,Q9C0H2,Q9HD20,P51790,P51798,P21281 11
Glycosphingolipid metabolism 0.784385229202635 2.6275148526834595 0.0086011086885526 0.9999920271266018 0.8740439357402792 15 A0FGR8,P16278,P04062,P10619,P06280,P07602,P17900,Q13510,P06865 9
Mitochondrial protein import 0.585931272922023 2.564777300516049 0.0103242045387434 0.9999992502482796 0.8740439357402792 34 Q9NS69,Q99595,Q15388,O14925,Q10713,Q8N4H5,Q13505,Q5JRX3,P21796,Q9NX63,Q9Y5J7,O75431 12
Synthesis of pa 0.861483294144259 2.457936929559683 0.0139737712563241 0.9999999950520264 0.8740439357402792 8 Q9NPH0 1
Rac2 gtpase cycle 0.5546844406138194 2.3585735617961685 0.0183453234153889 0.9999999999881988 0.8740439357402792 32 P02786,Q86XL3,Q13505,Q14739,Q9H0H5,O15173,Q7L576 7
Cholesterol biosynthesis 0.7296857075962504 2.343954667193022 0.0190804903715753 0.9999999999957366 0.8740439357402792 15 Q9BWD1,Q14739,Q16850,Q14534,Q15392,P48449,P37268,Q9UBM7 8
Glycosaminoglycan metabolism 0.7742833906384516 2.3244237121341196 0.0201027959096378 0.9999999999989664 0.8740439357402792 12 P16278,P54802,O43505,Q8TB61,P15586,P06865 6
Stimuli sensing channels 0.8283699963024092 2.2594949015579093 0.0238526170962334 0.9999999999999944 0.8740439357402792 7 P51790,Q96PU5,Q9C0H2 3
Metabolism of porphyrins 0.8154292304445441 2.2569042869291653 0.0240140561224828 0.9999999999999954 0.8740439357402792 8 Q7KZN9,P22830,P30519,P09601 4
Phospholipid metabolism 0.5562092408800446 2.242889811929701 0.0249039209083388 0.9999999999999988 0.8740439357402792 40 Q9NPH0,Q8NF37,O95674,Q9BTU6,Q8NCC3,Q9NQZ5,Q6P1A2,Q8IV08,P35790,P48651 10
Pink1 prkn mediated mitophagy 0.8090294065465762 2.175590532587569 0.0295858918922888 1.0 0.8740439357402792 7 Q9NS69,P21796 2
Selective autophagy 0.5406138845683991 2.139638305204042 0.0323840084631152 1.0 0.8740439357402792 28 Q9NS69,Q15388,Q8N4H5,P50542,P04350,P21796,P07900,P08670,P68371,Q13885,Q8IWA4,P54619 12
Mitochondrial calcium ion transport 0.686537899250964 2.113265230812678 0.0345780728871019 1.0 0.8740439357402792 15 Q9BPX6,Q9Y277,P21796,P45880,O95202,Q8WWC4,Q99623 7
Synthesis of pc 0.8534965866506625 2.05254524315634 0.040116702829666 1.0 0.9082674844982191 5 Q9NQZ5,P35790 2
Keratan sulfate keratin metabolism 0.8500419268979338 2.038396061390278 0.0415103398737135 1.0 0.9082674844982191 5 P06865,P16278,O43505 3
Mitophagy 0.7392626069397735 2.022751713765315 0.0430987522592531 1.0 0.9082674844982191 10 Q9NS69,P21796 2
Copi dependent golgi to er retrograde traffic 0.5344775846911038 1.994338027260667 0.0461151261445011 1.0 0.9082674844982191 45 Q86Y91,O14579,Q9P2W9,P24390,P04350,Q9BVK6,O75396,Q9H0H5,O15260,Q15363,P49755,Q9Y3B3,P68371,Q9BVA1,Q13885,Q8N6T3,P52732 17
Heme degradation 0.8374178331451301 1.9865128502551064 0.0469764074116541 1.0 0.9101162151381792 5 P30519,P09601 2
Rac3 gtpase cycle 0.507087866029884 1.957801313898634 0.0502533312012831 1.0 0.926378208667791 30 P02786,Q9UQB8,Q14739,Q9H0H5,O15173,Q7L576 6
Vitamin d calciferol metabolism 0.9329381252315684 1.9140507655547505 0.0556136695298183 1.0 0.926378208667791 3 Q99538,P04062 2
Transport of inorganic cations anions and amino acids oligopeptides 0.7268830404641193 1.9075968088364637 0.0564433479185972 1.0 0.926378208667791 9 Q9UBX3,P04920,Q70HW3,Q9H2H9 4
Autophagy 0.5078866014139176 1.89179494232644 0.0585183074411665 1.0 0.926378208667791 38 Q9NS69,Q15388,Q8N4H5,Q9NT62,P50542,P04350,P21796,P07900,P08670,O43633,P42345,Q13885,Q8IWA4,P68371,P54619 15
Activation of ampk downstream of nmdars 0.7538615218010174 1.8872555474126311 0.0591259622863586 1.0 0.926378208667791 6 Q13885,P54619,P04350,P68371 4
Cristae formation 0.5658725348186731 1.8846113565498244 0.0594823279272966 1.0 0.926378208667791 20 Q13505,Q5XKP0,Q9BUR5,Q9NX63,O75964,P56385,P24539,O75431,Q6UXV4 9
Mucopolysaccharidoses 0.8724981467753965 1.8786921919168065 0.060286534578624 1.0 0.926378208667791 4 P15586,P16278,P54802 3
Rhog gtpase cycle 0.4977044107135751 1.8741247273058856 0.0609132358746065 1.0 0.926378208667791 34 P02786,Q13190,Q86XL3,Q14739,O95202,O15173,Q7L576 7
Heparan sulfate heparin hs gag metabolism 0.8663397296424549 1.8543851278398027 0.0636840809693308 1.0 0.926378208667791 4 P16278,P54802 2
Peptide ligand binding receptors 0.7405027021857972 1.8282328508763663 0.0675146127032404 1.0 0.926378208667791 6 P42892,P07602,Q9NZJ7 3
Class a 1 rhodopsin like receptors 0.7405027021857972 1.8282328508763663 0.0675146127032404 1.0 0.926378208667791 6 P42892,P07602,Q9NZJ7 3
Transport of bile salts and organic acids metal ions and amine compounds 0.9103371619118216 1.8251526953313513 0.0679779900397241 1.0 0.926378208667791 3 Q8NEW0,P35613 2
Diseases of carbohydrate metabolism 0.726824303828171 1.809696733049592 0.070342829437326 1.0 0.926378208667791 7 P15586,P10253,P54802,P16278 4
Response to elevated platelet cytosolic ca2 0.5014624228671198 1.8057793790715564 0.070952807721649 1.0 0.926378208667791 27 Q9NUQ9,Q08380,P07602,Q9NZJ7,Q8NBX0,Q9NTK5,O43852,O94919,Q6UXV4 9
Rhoa gtpase cycle 0.4966106715285386 1.800220542273438 0.0718258214425064 1.0 0.926378208667791 38 P02786,Q13190,Q14739,P41440,Q9H0H5,O15173,Q8NBN3,P30519 8
Class i peroxisomal membrane protein import 0.7125477623032803 1.7899968246504734 0.0734544218687858 1.0 0.926378208667791 8 P51648,Q9NR77,P40855 3
Ire1alpha activates chaperones 0.5329994138930831 1.7780427787923778 0.0753968292143971 1.0 0.926378208667791 21 Q8N6T3,Q9NWM8,P35611,P43307,O95070,P61421,Q13217,Q9Y5M8,O14773 9
Ras processing 0.7836088054076193 1.7623114806504103 0.0780166852066268 1.0 0.926378208667791 5 O43924 1
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6929403666218785 1.7463847978463514 0.0807441097587249 1.0 0.926378208667791 9 Q9BU89,O60725,P49366 3
Pre notch processing in golgi 0.8903297517599142 1.7459951258619015 0.0808117987995695 1.0 0.926378208667791 3 Q15363,Q9UBV2 2
Keratan sulfate degradation 0.8354198845933065 1.7315939452363216 0.0833458850151873 1.0 0.926378208667791 4 P16278,P06865 2
Synaptic adhesion like molecules 0.7149315899816657 1.7142577323646846 0.0864814021559157 1.0 0.926378208667791 6 O95197 1
Unwinding of dna 0.667572236606536 1.674597285073386 0.0940132723169808 1.0 0.926378208667791 10 Q14566,P33991 2
Hs gag degradation 0.8721748795850367 1.6738288946430215 0.0941642318689872 1.0 0.926378208667791 3 P16278,P54802 2
Sphingolipid de novo biosynthesis 0.6762551113892397 1.6661773921341008 0.0956780875033502 1.0 0.926378208667791 9 P51648,O95470,Q96G23,O15269,Q06136 5
Abc family proteins mediated transport 0.5035846666209134 1.653391765816111 0.0982511575896538 1.0 0.926378208667791 51 O75477,P33527,P49721,Q99436,O75832,P20618,O75027,O00231,P28072,P28074,O94905,P60900,Q9UBV2,Q9BUN8,P08183,P40855,P28070,P61289 18
Peptide hormone metabolism 0.6436766905122757 1.6087875364692827 0.1076628070936875 1.0 0.9505179260777646 11 P67812 1
Activation of the pre replicative complex 0.6321770030668163 1.6069310888014223 0.1080694856864097 1.0 0.9505179260777646 12 O75419,Q14566,P33991 3
Gap junction assembly 0.7441891201665902 1.5951607373437369 0.1106762961910332 1.0 0.9505179260777646 5 Q13885,P04350,P68371 3
Transport of connexons to the plasma membrane 0.7441891201665902 1.5951607373437369 0.1106762961910332 1.0 0.9505179260777646 5 Q13885,P04350,P68371 3
Ros and rns production in phagocytes 0.6533734909174823 1.5552192603781831 0.1198938587221911 1.0 0.9505179260777646 9 Q9Y487 1
Gpcr ligand binding 0.6486402553543307 1.5321351519199404 0.1254890869289164 1.0 0.9505179260777646 9 P42892,P07602,Q9NZJ7 3
Intra golgi traffic 0.6475041153154424 1.5265877535919978 0.1268635541572338 1.0 0.9505179260777646 9 O00461,Q13190,O95249 3
Striated muscle contraction 0.7259072249906274 1.5169144405258428 0.1292882872175127 1.0 0.9505179260777646 5 Q9NYL9,P08670,P09493 3
Signaling by erbb4 0.6628338278931566 1.4783186371696555 0.1393225115230776 1.0 0.9505179260777646 6 P49768,P16949,Q92542,P62993,P61201 5
Kinesins 0.5171373078116892 1.459224097962311 0.144503438284631 1.0 0.9505179260777646 19 Q86Y91,P04350,Q9H0H5,P68371,Q13885,P52732 6
Protein localization 0.5101521990177034 1.4570359859414028 0.145106446983422 1.0 0.9505179260777646 68 Q9NS69,Q99595,P51648,O15254,Q15067,P21796,O14925,Q15388,P46379,Q8N4H5,O00116,Q13505,Q9BY49,Q13011,P40855,O75381,Q13190,P50402,Q9NX63,P09601,Q9NR77,O75431 22
Cargo concentration in the er 0.5918934519404718 1.4516775054704212 0.1465912968248954 1.0 0.9505179260777646 13 Q12907,Q13190,Q15363,O75396,Q96PC5,O95487 6
Nr1h2 and nr1h3 mediated signaling 0.7062865293869095 1.4325037269635368 0.151999712262056 1.0 0.9505179260777646 5 Q8NB78,Q9HCE1 2
Transferrin endocytosis and recycling 0.6086103785950528 1.4285415619477568 0.1531360407162165 1.0 0.9505179260777646 11 P02786,Q9Y487,Q93050,Q15904,P21281 5
Sialic acid metabolism 0.7601097029147512 1.4280748794578633 0.1532703070782632 1.0 0.9505179260777646 4 P16278 1
Abc transporter disorders 0.4564486748772156 1.4188701698239206 0.1559368704747976 1.0 0.9505179260777646 41 O75477,P49721,Q99436,O75832,P20618,O00231,P28072,P28074,O94905,P60900,Q9UBV2,P28070,P61289 13
Defective cftr causes cystic fibrosis 0.4564486748772155 1.4188701698239206 0.1559368704747976 1.0 0.9505179260777646 41 O75477,P49721,Q99436,O75832,P20618,O00231,P28072,P28074,O94905,P60900,Q9UBV2,P28070,P61289 13
Peroxisomal lipid metabolism 0.6158780496112835 1.416247521831163 0.1567030466726455 1.0 0.9505179260777646 10 P51648,Q15067,O15254 3
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.8054835124120074 1.4066751314594812 0.159523743197699 1.0 0.9505179260777646 3 P31749,P00374 2
O linked glycosylation 0.8048343641945616 1.4040645841425652 0.1602996185539731 1.0 0.9505179260777646 3 O43505 1
O linked glycosylation of mucins 0.8048343641945616 1.4040645841425652 0.1602996185539731 1.0 0.9505179260777646 3 O43505 1
Assembly and cell surface presentation of nmda receptors 0.6109183353466401 1.3911896921137092 0.1641679121700139 1.0 0.9505179260777646 10 P07196,Q13885,P04350,P68371 4
Processing of smdt1 0.610538866779252 1.389270813269918 0.1647504155987396 1.0 0.9505179260777646 10 Q9BPX6,Q10713,Q9UJZ1,Q9Y4W6,Q8WWC4,Q99623 6
Insulin receptor recycling 0.6101871872901103 1.387492245039047 0.1652917142105763 1.0 0.9505179260777646 10 Q9Y487 1
Transport of vitamins nucleosides and related molecules 0.6159082571590512 1.3713954034842408 0.1702517295755741 1.0 0.9505179260777646 9 O00400,Q99808,P12236,P12235,Q8TB61,Q9Y289 6
Intraflagellar transport 0.5957620486045979 1.3618880292997295 0.1732332245747647 1.0 0.9505179260777646 11 P04350,Q7Z4L5,A0AVF1,Q9BVA1,Q13885,P68371 6
Recruitment of numa to mitotic centrosomes 0.4328346613185153 1.3484049906674618 0.1775281596932407 1.0 0.9505179260777646 30 Q14203,P07437,O75935,O43805,P04350,P07900,Q13561,Q15691,O94927,Q9BSJ2,Q9BVA1,P68371,Q13885,P53350 14
Constitutive signaling by overexpressed erbb2 0.7906632085957755 1.3470588869836015 0.1779612678830848 1.0 0.9505179260777646 3 Q16543,P07900 2
Cargo trafficking to the periciliary membrane 0.5132819616482038 1.344965164471735 0.1786364844476093 1.0 0.9505179260777646 18 O43924,A6NIH7 2
Iron uptake and transport 0.5124353399603211 1.3395148841136564 0.1804031122753018 1.0 0.9505179260777646 18 Q93050,P30519,Q9Y487 3
Heme biosynthesis 0.7881841883223826 1.337085021444992 0.1811948858654657 1.0 0.9505179260777646 3 Q7KZN9 1
Recruitment of mitotic centrosome proteins and complexes 0.4432906861686321 1.3217689337146692 0.1862451061599193 1.0 0.9505179260777646 26 Q14203,P07437,O75935,O43805,P04350,P07900,P06493,Q13561,O94927,Q9BSJ2,Q15691,P68371,P62258,P53350 14
Energy dependent regulation of mtor by lkb1 ampk 0.7332914189257518 1.3189424865638546 0.1871883407977912 1.0 0.9505179260777646 4 Q9Y376,P54619 2
Alpha oxidation of phytanate 0.7812716184453822 1.3092747121617154 0.1904413123446833 1.0 0.9505179260777646 3 P51648 1
Diseases of glycosylation 0.5630686906766181 1.293498026171492 0.1958388663000545 1.0 0.9505179260777646 13 P10619,Q9BV10,P16278,O43505 4
Mtor signalling 0.5780786064827472 1.2697086260086774 0.2041884390068786 1.0 0.9774358848839666 11 Q9Y376,P62942,P31749,P42345,P54619 5
Basigin interactions 0.6138229817294135 1.2526898656216376 0.2103185955932951 1.0 0.9926583428919548 6 P35613 1
Copi mediated anterograde transport 0.4471932536429484 1.2460000836885787 0.2127643644590291 1.0 0.9926583428919548 47 Q13190,O75935,O14579,P24390,Q9BVK6,Q15363,Q13561,Q9Y3B3,P68371,O95249 10
Metabolism of fat soluble vitamins 0.7654448678390706 1.2456308861594283 0.2128999377449232 1.0 0.9926583428919548 3 Q8N0U8 1
Regulation of tp53 expression and degradation 0.6053281540375327 1.2445876809336491 0.2132833509641098 1.0 0.9926583428919548 7 P06493,P31749,P30154,P42345 4
Post chaperonin tubulin folding pathway 0.5773273515462685 1.2205195474950967 0.2222679839645778 1.0 1.0 10 P04350,Q99426,Q9BTW9,Q9BUF5,O75347,Q9BVA1,P68371,Q13885 8
Intra golgi and retrograde golgi to er traffic 0.4967570972085739 1.208299097663836 0.2269322354326872 1.0 1.0 78 Q8N2H4,O14579,P24390,Q9Y3B3,O95249,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q8N1B4,Q13885,O00461,P52732,Q86Y91,O95721,Q13190,Q9UJW0,O15260,Q9BVA1,Q8N6T3,Q9P2W9,Q10472,Q15363,Q9H0H5,P49755,P11717,Q6NUQ1 29
Activation of atr in response to replication stress 0.5369702959505812 1.2049767551927473 0.2282122755409663 1.0 1.0 14 O75419,Q14566,P33991 3
Nuclear signaling by erbb4 0.7045959970348548 1.201961705658655 0.2293783652030696 1.0 1.0 4 P16949,P61201,Q92542 3
Ion transport by p type atpases 0.5648137485688511 1.2002874035657594 0.2300277401614048 1.0 1.0 11 Q9HD20,P16615,P05023 3
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.7490782976637099 1.1799177881818488 0.2380329142936377 1.0 1.0 3 Q8NB78 1
Slc transporter disorders 0.4114217384998775 1.1643864757130526 0.2442674258738764 1.0 1.0 33 Q8NFH4,Q7Z3B4,P35613,O00400,P53985,Q8N1F7,Q9BTX1 7
Cilium assembly 0.4443617625104979 1.1451416483970578 0.2521504853552299 1.0 1.0 52 P50991,O43805,P07900,O94927,O43924,A6NIH7,P07437,O75935,P04350,Q13561,P68371,Q13885,P53350,Q10713,Q9BVA1,Q92973,Q7Z4L5,Q15691,A0AVF1 19
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.6381164256581288 1.1370204033530231 0.2555297563243384 1.0 1.0 5 P12236,P05141,P12235,Q99808 4
Regulation of runx3 expression and activity 0.4135684962284384 1.133684430520911 0.256926942817272 1.0 1.0 36 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Signaling by insulin receptor 0.5137402386727533 1.1305249545298337 0.258255089415677 1.0 1.0 15 Q9Y487 1
Golgi to er retrograde transport 0.4636726455978724 1.129973345674289 0.258487456011814 1.0 1.0 64 O14579,P24390,Q9Y3B3,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q13885,P52732,Q86Y91,Q9UJW0,O15260,Q9BVA1,Q8N6T3,Q9P2W9,Q10472,Q9H0H5,Q15363,P49755,Q6NUQ1 22
Carboxyterminal post translational modifications of tubulin 0.5869241173333141 1.1279497632476136 0.2593411359096773 1.0 1.0 6 Q13885,P04350,P68371 3
Peroxisomal protein import 0.4795770875859715 1.126628038278637 0.2598997793915698 1.0 1.0 18 O15254,O00116,Q15067,Q9BY49,Q13011 5
Amino acid transport across the plasma membrane 0.6839381761070538 1.117822305246208 0.2636428931008794 1.0 1.0 4 Q9H2H9 1
Pre notch expression and processing 0.5708457055393568 1.1122665325570391 0.2660235690119485 1.0 1.0 8 Q9UBV2,Q15363 2
Diseases associated with glycosylation precursor biosynthesis 0.5831168297806396 1.110273144881296 0.2668813417402846 1.0 1.0 6 P16278 1
Hedgehog ligand biogenesis 0.4159574049455591 1.1057345916034111 0.268841413053257 1.0 1.0 39 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,Q9UBV2,P07237,P28070,P61289 11
Glutamate neurotransmitter release cycle 0.7304281183646087 1.1052672478839722 0.2690438052757933 1.0 1.0 3 Q96QD8 1
Metabolism of polyamines 0.4130419987463842 1.0966891061451898 0.2727773202197889 1.0 1.0 38 P49721,Q9H2H9,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 10
Cdt1 association with the cdc6 orc origin complex 0.4075268710152185 1.0651640623736809 0.2868016932890764 1.0 1.0 37 P49721,Q99436,Q9Y619,O75832,P20618,P28072,P28074,P60900,P28070,P61289 10
Anchoring of the basal body to the plasma membrane 0.4097898974188424 1.0533524098312794 0.292179506897692 1.0 1.0 26 Q14203,P07437,O75935,O43805,P04350,P07900,P06493,Q13561,O94927,Q15691,P68371,P62258,P53350 13
Rac1 gtpase cycle 0.4023457715845296 1.02025783394639 0.3076061954908284 1.0 1.0 37 P02786,Q9UQB8,Q14739,Q9H0H5,Q96F07,Q7L576 6
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5044745433905613 1.019146328638804 0.3081335025272298 1.0 1.0 14 Q13217,O43852,Q02818,Q07065,P07237 5
Sema4d induced cell migration and growth cone collapse 0.6106785317018879 1.0179957758674485 0.3086799635217354 1.0 1.0 5 P35579,P35580,Q7Z406,Q13464 4
Epha mediated growth cone collapse 0.6106785317018879 1.0179957758674485 0.3086799635217354 1.0 1.0 5 P35579,P35580,Q7Z406,Q13464 4
Aurka activation by tpx2 0.4043173358017022 1.0091735253870635 0.3128914211090627 1.0 1.0 26 Q14203,P07437,O75935,O43805,P04350,P07900,P06493,Q13561,O94927,Q15691,P68371,P62258,P53350 13
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.555141527478435 1.0063091534805622 0.314266878667254 1.0 1.0 7 P30260,Q96DE5,Q9UJX3,Q9UJX4 4
Notch4 activation and transmission of signal to the nucleus 0.7043349388662568 1.001503389272973 0.3165835023767012 1.0 1.0 3 Q92542,P63104 2
Noncanonical activation of notch3 0.7043349388662568 1.001503389272973 0.3165835023767012 1.0 1.0 3 Q92542,P67809 2
Acyl chain remodelling of pc 0.9218518518518536 1.00057297281517 0.3170333020069447 1.0 1.0 2 Q8NF37 1
Dna damage recognition in gg ner 0.4711349272692818 0.99992985278304 0.3173444561993845 1.0 1.0 17 Q16531 1
Endosomal vacuolar pathway 0.7035686526481126 0.9984720041062968 0.3180505333559571 1.0 1.0 3 Q9UIQ6 1
Orc1 removal from chromatin 0.4160912102532405 0.996360168385317 0.3190751789603954 1.0 1.0 46 P49721,Q99436,Q9Y619,O75832,P20618,P28072,P28074,P60900,P33991,Q14566,P28070,P61289 12
Cytochrome p450 arranged by substrate type 0.7027877298705805 0.995383801943152 0.3195496336442729 1.0 1.0 3 Q16850 1
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.470193153289279 0.9939892790830696 0.3202280869041856 1.0 1.0 17 P50991,P04350,Q9UHV9,Q9BVA1,P68371,Q13885,Q99471,O15212 8
Rhoc gtpase cycle 0.4051459017168517 0.9804687861916886 0.3268547700476032 1.0 1.0 24 P02786,Q14739,P41440,Q9H0H5 4
Metabolism of cofactors 0.6498112375042447 0.9794974565869778 0.3273342447075538 1.0 1.0 4 P31749,P00374 2
Signaling by notch4 0.4066913542176739 0.9623282305127218 0.3358847524634765 1.0 1.0 43 P49721,Q99436,O75832,P20618,P31749,P28072,Q92542,P28074,P60900,P28070,P61289 11
Proton coupled monocarboxylate transport 0.9100000000000006 0.9588765272873208 0.3376209509436094 1.0 1.0 2 P35613 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3986563937924801 0.940244257222786 0.3470922851285889 1.0 1.0 40 P49721,Q99436,P20618,Q03164,P28072,P28074,P60900,P28070,P61289 9
Degradation of axin 0.3905679425376534 0.9340292958791848 0.3502887813767015 1.0 1.0 36 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Cross presentation of soluble exogenous antigens endosomes 0.3905679425376534 0.9340292958791848 0.3502887813767015 1.0 1.0 36 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Transport of small molecules 0.5625614452183876 0.930116111513749 0.3523109697120954 1.0 1.0 147 Q9BPX6,Q70HW3,O00400,Q8N4V1,O75027,P38571,P21796,P45880,O00231,Q9C0H2,Q9UBV2,Q8TB61,Q9BUN8,Q99797,P30519,P61289,Q99623,P49721,P11166,Q9Y487,O15439,Q93050,Q9UJZ1,P20618,P16615,P61916,P28072,Q8WWC4,O94905,P28074,P60900,Q9HD20,P51790,P40855,O75477,P02786,O15118,Q9H2H9,Q99436,O75832,Q10713,Q8WTV0,P12236,P08183,P09601,P21281,Q8NEW0,P33527,Q96PU5,P04920,Q9Y277,P35613,Q9UBX3,P05023,P35611,O43242,O95202,P98194,Q15904,P53985,P51798,Q96QD8,P07237,P28070 64
Hyaluronan uptake and degradation 0.5897937133765949 0.9278340682743312 0.3534936490124556 1.0 1.0 5 P06865 1
Hyaluronan metabolism 0.5897937133765949 0.9278340682743312 0.3534936490124556 1.0 1.0 5 P06865 1
Protein protein interactions at synapses 0.504221846484684 0.9220770906039132 0.3564883657926918 1.0 1.0 12 O95197 1
Phase i functionalization of compounds 0.4938641471284494 0.9095723824503916 0.3630480689288715 1.0 1.0 13 O43169,Q16850 2
Switching of origins to a post replicative state 0.4175314241694913 0.902048824209552 0.3670309322808998 1.0 1.0 53 P49721,Q99436,Q9Y619,O75832,P20618,Q9UJX4,O00231,P28072,P28074,P60900,Q96DE5,P33991,Q14566,P28070,P61289 15
Degradation of dvl 0.3886319423056957 0.9010884278158594 0.3675413052425433 1.0 1.0 37 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Stabilization of p53 0.3880558630520152 0.8960759187117496 0.3702122175270288 1.0 1.0 37 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
G1 s dna damage checkpoints 0.3880558630520152 0.8960759187117496 0.3702122175270288 1.0 1.0 37 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Flt3 signaling 0.6277307772384855 0.890857557747663 0.3730055920554227 1.0 1.0 4 P31749 1
Synthesis of pg 0.8896296296296329 0.8879611781707007 0.3745616343356022 1.0 1.0 2 Q8IV08 1
Regulation of ras by gaps 0.3885297487135273 0.8842130806036127 0.3765811984778622 1.0 1.0 38 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Interleukin 4 and interleukin 13 signaling 0.4877855315719739 0.8758613866780326 0.3811053932446056 1.0 1.0 13 P08670,P31749,P09601 3
Downstream signaling events of b cell receptor bcr 0.3888261638114282 0.8708900956172616 0.383814165222835 1.0 1.0 39 P49721,Q99436,P62942,O75832,P20618,P28072,P28074,P60900,P28070,P61289 10
Complex i biogenesis 0.3867950295103917 0.8674328034301352 0.3857049148729159 1.0 1.0 26 Q9P0J0,Q9Y6M9,Q86Y39,O96000,O43676 5
Plasma lipoprotein clearance 0.4934607004463008 0.864111565071607 0.3875266064505303 1.0 1.0 12 Q8WTV0,O15118 2
Transcriptional regulation by ventx 0.507186179946537 0.8620854464333326 0.3886404994101913 1.0 1.0 10 P30260,Q9UJX3,Q9UJX4,Q96DE5,Q9HCE1 5
Negative regulation of notch4 signaling 0.3892909421209921 0.8591099469334873 0.3902798599940458 1.0 1.0 40 P49721,Q99436,O75832,P20618,P31749,P28072,P28074,P60900,P28070,P61289 10
Dna replication pre initiation 0.4119690366231804 0.854657221158776 0.3927409396342805 1.0 1.0 53 P49721,Q99436,Q9Y619,O75832,P20618,O75419,P28072,P28074,P60900,P33991,Q14566,P28070,P61289 13
Unfolded protein response upr 0.3778304603654025 0.8390667262206303 0.4014318666649656 1.0 1.0 35 Q92945,Q8N6T3,Q9NWM8,P35611,P43307,O95070,P61421,Q13217,Q9Y5M8,O14773 10
Pyruvate metabolism 0.4547831534726866 0.8363650995558998 0.4029495402729064 1.0 1.0 16 P21796,P35613 2
Retrograde transport at the trans golgi network 0.4954529762913136 0.836347372590929 0.4029595099649534 1.0 1.0 11 Q8N1B4,Q8N2H4,P11717,P20645 4
Golgi associated vesicle biogenesis 0.3838173598785135 0.8271765431687029 0.4081370048265438 1.0 1.0 25 P02786,Q9BXS5,Q9Y5X1,O75976,Q9Y5X3,O60749,P50570,P11717 8
Signal regulatory protein family interactions 0.6595516964348668 0.82655501281463 0.4084893248375016 1.0 1.0 3 P62993 1
Respiratory electron transport 0.3961987673195885 0.8254791076488538 0.4090996391806518 1.0 1.0 46 Q7L592,Q9P0J0,Q9Y6M9,Q86Y39,Q16134,P00403,O14949,P13073,O96000,Q9UDW1,O43676 11
Ub specific processing proteases 0.4272494865968884 0.8240194947990448 0.4099284810781329 1.0 1.0 64 Q15388,P49721,Q86UV5,Q99436,Q9Y277,O75832,P20618,Q96RU2,P21796,P45880,P28072,P28074,P60900,Q96K76,Q9UPU5,P28070,P61289 17
Plasma lipoprotein assembly remodeling and clearance 0.4701403411798153 0.822825771374983 0.4106070790345519 1.0 1.0 14 Q8WTV0,P07237,P61916,O15118 4
Regulation of hmox1 expression and activity 0.3894211957794059 0.7978814476942764 0.4249392904191342 1.0 1.0 44 P49721,Q99436,Q8TCT9,P20618,P28072,P28074,P60900,P09601,P28070,P61289 10
Metabolism of steroids 0.3799710209917272 0.7940429035693325 0.4271704550172193 1.0 1.0 39 P04062,Q9BWD1,Q16850,Q14739,Q14534,Q15392,Q99538,P48449,P37268,Q53GQ0,Q15800,P30536,Q9H4L5,Q9UBM7,P38435 15
Cargo recognition for clathrin mediated endocytosis 0.3720447179607168 0.7835332761360152 0.4333140207923103 1.0 1.0 28 Q14108,P02786,Q9BT78 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.5114366030484556 0.779318180089798 0.435792307933762 1.0 1.0 6 Q9NR77 1
Tysnd1 cleaves peroxisomal proteins 0.552572338967152 0.7691336089853026 0.4418139981486879 1.0 1.0 5 Q15067 1
Transcriptional regulation by runx3 0.3784159767485972 0.7648837670892163 0.4443407609419623 1.0 1.0 40 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Trans golgi network vesicle budding 0.3656427648305905 0.7647267055491368 0.4444343003501791 1.0 1.0 33 P02786,O14976,Q9BXS5,Q9Y5X1,O75976,Q9Y5X3,O60749,P50570,O43633,P11717,P15586 11
Dna strand elongation 0.3776583594239656 0.752989572135723 0.4514561803423276 1.0 1.0 23 O75419,Q14566,P33991 3
Metabolism of folate and pterines 0.4960286979485739 0.7501645001127837 0.4531556365824751 1.0 1.0 8 Q9H2D1,P41440 2
Regulation of pten stability and activity 0.3766833000104917 0.7498826153250577 0.4533254057049043 1.0 1.0 40 P49721,Q99436,O75832,P20618,P31749,P28072,P28074,P60900,P28070,P61289 10
Constitutive signaling by akt1 e17k in cancer 0.6374278917918725 0.7423577769174118 0.4578705944928725 1.0 1.0 3 P31749 1
Asymmetric localization of pcp proteins 0.3687964050971359 0.7285078361554788 0.4663027735475453 1.0 1.0 37 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Signaling by the b cell receptor bcr 0.3753302979519284 0.7226487832891283 0.4698956890546628 1.0 1.0 41 P49721,Q99436,P62942,P20618,P28072,P28074,P60900,P28070,P61289 9
Scf skp2 mediated degradation of p27 p21 0.3716942150307121 0.7222833320932753 0.4701202984304102 1.0 1.0 39 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Cdc42 gtpase cycle 0.3707168120716536 0.710315862364992 0.4775082853953076 1.0 1.0 24 Q14739,Q9UQB8,Q9H0H5 3
Cyclin a cdk2 associated events at s phase entry 0.3736103395983191 0.7077979538113416 0.4790707372426555 1.0 1.0 41 P49721,Q99436,O75832,P20618,P31749,P28072,P28074,P60900,P28070,P61289 10
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.3975534878370144 0.7026287835665302 0.4822871198732739 1.0 1.0 55 Q7L592,Q9P0J0,Q9Y6M9,Q86Y39,Q16134,P00403,O14949,P20674,P13073,P56385,O96000,O75964,Q9UDW1,O95168,P24539,O43676 16
Cytoprotection by hmox1 0.4073531006689609 0.6991419501595026 0.4844633242157945 1.0 1.0 61 P33527,P49721,Q99436,Q8TCT9,P20618,O75832,O00231,P28072,P28074,P60900,P13073,P09601,P00403,P30519,P28070,P61289 16
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5322332323611052 0.6841464896663528 0.4938826679425347 1.0 1.0 5 Q5KU26 1
Lipophagy 0.6216338714530839 0.6834818837483416 0.4943023938836286 1.0 1.0 3 P54619 1
Platelet calcium homeostasis 0.5746113415001359 0.6828129593484613 0.4947250396881435 1.0 1.0 4 P16615,P23634 2
Reduction of cytosolic ca levels 0.5746113415001359 0.6828129593484613 0.4947250396881435 1.0 1.0 4 P16615,P23634 2
Signaling by notch 0.3926554663674856 0.6756839497604861 0.4992413284776362 1.0 1.0 54 P49721,Q99436,O75832,P20618,P16615,P31749,Q15363,P28072,Q92542,P28074,P60900,Q9UBV2,P28070,P61289 14
Disorders of transmembrane transporters 0.4248435486385284 0.6658694769503701 0.5054945317355537 1.0 1.0 74 O00400,O00231,Q9UBV2,Q9BUN8,Q9BTX1,P61289,Q8NFH4,P49721,P20618,P28072,P28074,O94905,P60900,O75477,Q99436,O75832,P35613,P53985,P28070 19
Rna polymerase iii transcription initiation from type 1 promoter 0.4794063079777518 0.6516047541806468 0.5146561800040703 1.0 1.0 7 Q9Y5Q8,Q9Y5Q9,P62875,Q9UKN8,P19388,O14802 6
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3741005344963946 0.6509896628639938 0.515053159785305 1.0 1.0 45 P49721,Q99436,O75832,P20618,Q9UJX4,O00231,P28072,P28074,P60900,Q96DE5,P28070,P61289 12
Platelet activation signaling and aggregation 0.3743684421958524 0.6382610051101346 0.5233037914151282 1.0 1.0 46 Q9NUQ9,Q8N2K0,Q08380,P31749,P07602,Q9NZJ7,Q8NBX0,Q9NTK5,O43852,O94919,Q6UXV4 11
Hedgehog on state 0.3634973451428575 0.6359894409510758 0.5247833042911507 1.0 1.0 40 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Binding and uptake of ligands by scavenger receptors 0.4756473040887949 0.6344617203569747 0.525779541026995 1.0 1.0 7 Q5KU26 1
Copi independent golgi to er retrograde traffic 0.3604215453679593 0.6300815376014642 0.528641238324969 1.0 1.0 24 Q9UJW0,O75935,Q10472,P04350,Q13561,Q9BVA1,P68371,Q13885 8
Acyl chain remodelling of pg 0.810370370370377 0.6248861227741744 0.5320458008784974 1.0 1.0 2 Q8NF37 1
Integrin signaling 0.5173926658334148 0.623232998159639 0.5331314201846333 1.0 1.0 5 P31749 1
Platelet aggregation plug formation 0.5173926658334148 0.623232998159639 0.5331314201846333 1.0 1.0 5 P31749 1
Diseases associated with n glycosylation of proteins 0.5583913738468138 0.62147087454995 0.5342898520841746 1.0 1.0 4 Q9BV10 1
Er to golgi anterograde transport 0.4061833148518004 0.6057465134525574 0.5446830919446237 1.0 1.0 67 O14579,P24390,Q96PC5,Q9Y3B3,O95249,Q12907,O15020,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q13885,Q13190,Q9UJW0,Q8IUR0,Q9BVA1,Q8N6T3,Q15363,P49755,O95487 22
The role of gtse1 in g2 m progression after g2 checkpoint 0.3736192318911838 0.6021412190927095 0.5470801390980897 1.0 1.0 48 P49721,Q99436,O75832,P20618,P04350,P07900,O43242,O00231,P28072,P28074,P60900,Q15691,P68371,Q13885,P28070,P53350,P61289 17
Cd28 dependent pi3k akt signaling 0.8022222222222252 0.599382184563029 0.5489180544049488 1.0 1.0 2 P31749 1
Regulation of lipid metabolism by pparalpha 0.4289454837207592 0.5909226167900271 0.5545722712629839 1.0 1.0 14 Q15067,P23786 2
Signaling by gpcr 0.3456862339408106 0.5906815790210659 0.5547337928380092 1.0 1.0 33 Q15418,Q8N2K0,P31749,P07602,Q9NZJ7,P52292,P42892,P30154 8
Ldl clearance 0.4512511501090768 0.5821427476340347 0.5604705333841102 1.0 1.0 10 P61916,O15118 2
Rhobtb3 atpase cycle 0.5433654558932637 0.5658857471897574 0.5714714511012129 1.0 1.0 4 P51151,O60664,O14964 3
Mtorc1 mediated signalling 0.4563159915365661 0.5638686719423001 0.5728435120695483 1.0 1.0 8 P42345,P62942 2
Synthesis of substrates in n glycan biosythesis 0.4334074360693989 0.5466925605401973 0.5845899660978977 1.0 1.0 12 P16278 1
Postmitotic nuclear pore complex npc reformation 0.349922447264996 0.5406524175026801 0.5887471811117446 1.0 1.0 23 Q8NFH4,Q7Z3B4,Q8NFH5,Q92973,P55735,Q8N1F7,Q9BVL2,Q9BTX1 8
Uch proteinases 0.3590854679523019 0.537874826373622 0.5906634688487065 1.0 1.0 44 P49721,Q8NB78,Q99436,P20618,P28072,P28074,P60900,P28070,P61289 9
Signaling by erbb2 ecd mutants 0.5319162591830764 0.524456215143733 0.5999612659147753 1.0 1.0 4 Q16543,P07900 2
Signaling by egfr in cancer 0.5319162591830764 0.524456215143733 0.5999612659147753 1.0 1.0 4 Q16543,P07900 2
Constitutive signaling by egfrviii 0.5319162591830764 0.524456215143733 0.5999612659147753 1.0 1.0 4 Q16543,P07900 2
Constitutive signaling by ligand responsive egfr cancer variants 0.5319162591830764 0.524456215143733 0.5999612659147753 1.0 1.0 4 Q16543,P07900 2
Signaling by erbb2 in cancer 0.5319162591830764 0.524456215143733 0.5999612659147753 1.0 1.0 4 Q16543,P07900 2
Phosphorylation of the apc c 0.4391138613510951 0.5233464655945345 0.6007331712659476 1.0 1.0 10 P30260,Q9UJX3,Q9UJX4,P06493,Q96DE5,P53350 6
Regulation of glucokinase by glucokinase regulatory protein 0.3434174588327489 0.518864148581572 0.6038554801970117 1.0 1.0 26 Q8NFH4,Q7Z3B4,Q8NFH5,Q9BW27,Q92621,Q99567,P35658,P49792,P55735,P12270,Q8N1F7,Q9BVL2,Q9BTX1 13
Sumoylation of sumoylation proteins 0.3434174588327489 0.518864148581572 0.6038554801970117 1.0 1.0 26 Q8NFH4,Q7Z3B4,Q8NFH5,Q9BW27,Q92621,Q99567,P35658,P49792,P55735,P12270,Q8N1F7,Q9BVL2,Q9BTX1 13
Sealing of the nuclear envelope ne by escrt iii 0.4367319648704689 0.5119265084453974 0.6087024449308736 1.0 1.0 10 Q13885,O43633,P04350,P68371 4
Degradation of gli1 by the proteasome 0.3471548589941651 0.5110771061779588 0.6092970660707586 1.0 1.0 39 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.4054912785883744 0.4990144282106138 0.6177692196654703 1.0 1.0 15 P10619,P16278 2
Cellular response to hypoxia 0.3455717930143199 0.4975910938998104 0.6187722823342716 1.0 1.0 39 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Transport to the golgi and subsequent modification 0.3960778566410102 0.4952593731883155 0.620417044787078 1.0 1.0 69 O14579,P24390,Q96PC5,Q9Y3B3,O95249,Q12907,O15020,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q13885,Q13190,Q9UJW0,Q8IUR0,Q9BVA1,Q8N6T3,Q15363,P49755,O95487 22
Synthesis of very long chain fatty acyl coas 0.4437192057405362 0.4920749588459749 0.6226663538469719 1.0 1.0 7 Q9P035 1
Muscle contraction 0.3423337078188256 0.4907648306519867 0.6235927871972549 1.0 1.0 24 P16615,P23634,P05023,P08670,P09493,Q9NYL9,P06753 7
Gap junction trafficking and regulation 0.4206711375152348 0.4818226672937173 0.6299319254989071 1.0 1.0 12 Q9BVA1,Q13885,P04350,P68371 4
Notch3 activation and transmission of signal to the nucleus 0.5172303361083601 0.4726451675218761 0.6364663523763887 1.0 1.0 4 Q92542,P67809 2
Fceri mediated nf kb activation 0.3434691403457587 0.4648267027794457 0.642055563655767 1.0 1.0 40 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Formation of atp by chemiosmotic coupling 0.4301250548395381 0.4615796592340493 0.6443827840995051 1.0 1.0 9 P56134,P36542,O75964,P56385,P24539 5
Creb phosphorylation 0.7462962962963031 0.435029911724799 0.66354071597919 1.0 1.0 2 Q15418 1
Cs ds degradation 0.7451851851851925 0.4319792842332937 0.665756469462286 1.0 1.0 2 P06865 1
Chondroitin sulfate dermatan sulfate metabolism 0.7451851851851925 0.4319792842332937 0.665756469462286 1.0 1.0 2 P06865 1
Diseases associated with glycosaminoglycan metabolism 0.7451851851851925 0.4319792842332937 0.665756469462286 1.0 1.0 2 P06865 1
Release of apoptotic factors from the mitochondria 0.5487176366756672 0.4308767935857838 0.6665579579864984 1.0 1.0 3 O60443 1
Budding and maturation of hiv virion 0.421826419779557 0.409924070949578 0.6818616471782595 1.0 1.0 8 Q96PU5,O43633 2
Ptk6 regulates proteins involved in rna processing 0.73703703703704 0.4098940244931421 0.6818836889785844 1.0 1.0 2 P23246 1
Metabolism of steroid hormones 0.4981346656186344 0.4078266269535438 0.6834009635876455 1.0 1.0 4 P30536 1
Gab1 signalosome 0.5400649296954491 0.4036336003519624 0.6864821736132063 1.0 1.0 3 P62993 1
Antigen processing cross presentation 0.3479309708204622 0.4006811290826635 0.6886549061478866 1.0 1.0 47 P49721,P61289,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,Q9UIQ6 10
Enos activation 0.539106532935415 0.4006592207460238 0.6886710381915828 1.0 1.0 3 P31749 1
Downregulation of erbb2 signaling 0.4547558114767042 0.3815116437500158 0.7028236329154205 1.0 1.0 5 P31749,Q16543 2
Apc c cdc20 mediated degradation of cyclin b 0.4121453485962364 0.3811088487953876 0.7031224816451218 1.0 1.0 9 P30260,Q9UJX3,Q9UJX4,P06493,Q96DE5 5
Visual phototransduction 0.4899050385690461 0.3808859335021386 0.7032878906109317 1.0 1.0 4 Q6NUM9 1
Tgf beta receptor signaling activates smads 0.408564279189218 0.3805101683711855 0.7035667499338765 1.0 1.0 10 Q96PU5 1
Signaling by braf and raf1 fusions 0.3288588642439629 0.379649310805841 0.7042057518021538 1.0 1.0 22 Q9NRY5 1
Pi3k akt signaling in cancer 0.4156976112942943 0.3734706714624402 0.7087981696290371 1.0 1.0 7 P31749,P42345,P62993 3
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4132477190229744 0.3732601396412648 0.7089548400851833 1.0 1.0 8 P30260,Q96DE5,Q9UJX3,Q9UJX4 4
Rna polymerase iii transcription 0.4131403118039944 0.3728059502022959 0.7092928739868072 1.0 1.0 8 Q12789,Q9Y5Q8,Q9Y5Q9,P62875,Q9UKN8,P19388,O14802 7
Sumoylation of rna binding proteins 0.3183716537887328 0.3704384825186391 0.7110558050598019 1.0 1.0 30 Q8NFH4,Q7Z3B4,P61978,Q8NFH5,Q92621,Q99567,P35658,P55735,P07910,Q8N1F7,Q9BVL2,Q9BTX1 12
Interleukin 1 signaling 0.3345812330768665 0.3612788470848016 0.7178910049598466 1.0 1.0 42 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Rna polymerase iii transcription initiation from type 3 promoter 0.5235272323082613 0.3535807882745647 0.7236530741860925 1.0 1.0 3 P19388,O14802 2
Rna polymerase iii chain elongation 0.5235272323082613 0.3535807882745647 0.7236530741860925 1.0 1.0 3 P19388,O14802 2
Dna damage reversal 0.4807264640474564 0.3516113314094081 0.7251297659880644 1.0 1.0 4 Q6P6C2,Q8N3C0,Q9H1I8 3
Rnd1 gtpase cycle 0.3937277195732708 0.3494368658299309 0.7267613606005219 1.0 1.0 12 P51648,P02786,P38159,O75976 4
Rhod gtpase cycle 0.3219236383855198 0.3438022386768138 0.7309950165289383 1.0 1.0 25 Q14739,O15173,Q9H0H5 3
Sumoylation of ubiquitinylation proteins 0.3192627610160651 0.3400375592409527 0.733828243208573 1.0 1.0 27 Q8NFH4,Q7Z3B4,Q8NFH5,Q9BW27,Q92621,Q99567,P35658,P49792,P55735,P12270,Q8N1F7,Q9BVL2,Q9BTX1 13
Gastrin creb signalling pathway via pkc and mapk 0.4425179444721022 0.3382261972805656 0.7351927353987386 1.0 1.0 5 Q15418,P62993 2
Deubiquitination 0.3936173121756586 0.3347169747048882 0.7378385953948765 1.0 1.0 80 Q86UV5,P21796,P45880,P61289,Q15388,P49721,P20618,P28072,P28074,P60900,Q8NB78,Q99436,O75832,Q96K76,Q9UPU5,Q9Y277,O95630,Q96RU2,P28070 19
Nuclear import of rev protein 0.3132485029940183 0.3282780589272593 0.7427014322191043 1.0 1.0 30 P37198,Q9UKX7,P78406,P49792,O75694,Q14974,Q9BTX1,Q8NFH4,Q7Z3B4,Q8TEM1,Q12769,P35658,Q8N1F7,P55735,P12270,Q8NFH5,Q9BW27,Q92621,P52948,P57740,P06748,Q8WUM0,Q96EE3,Q5SRE5,Q99567,P18754,P62826,Q9BVL2,Q9NRG9 29
Tcr signaling 0.3322868437221282 0.3281941422321187 0.7427648766082351 1.0 1.0 43 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Depolymerisation of the nuclear lamina 0.4007112194466352 0.3211225938087634 0.7481174889211784 1.0 1.0 8 P50402,P42167,P06493,Q9Y2U8 4
Bicarbonate transporters 0.696666666666671 0.308474205841748 0.7577215246580455 1.0 1.0 2 P04920 1
Export of viral ribonucleoproteins from nucleus 0.3130142109199877 0.3015203981555321 0.7630176978522307 1.0 1.0 28 P37198,Q9UKX7,P78406,P49792,O75694,Q9BTX1,Q8NFH4,Q7Z3B4,Q8TEM1,Q12769,P35658,Q8N1F7,P55735,P12270,O14980,Q8NFH5,Q9BW27,Q92621,P52948,P57740,Q8WUM0,Q96EE3,Q5SRE5,Q99567,P62826,Q9BVL2,Q9NRG9 27
Interleukin 1 family signaling 0.3299738541589391 0.2953561758135183 0.7677218073477348 1.0 1.0 44 P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289 9
Nade modulates death signalling 0.6903703703703694 0.2939472472047059 0.7687982139999683 1.0 1.0 2 P62258 1
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3926344291136606 0.2885366728662407 0.7729359626724777 1.0 1.0 8 Q15418 1
Antigen presentation folding assembly and peptide loading of class i mhc 0.3764348190262365 0.2883037215980212 0.7731142586247117 1.0 1.0 13 P10321,Q9NZ08 2
Cytosolic iron sulfur cluster assembly 0.4276836628511209 0.2879854748451033 0.7733578572818374 1.0 1.0 5 O75027 1
Activation of nmda receptors and postsynaptic events 0.3148335002657749 0.2826078095309333 0.7774774931459338 1.0 1.0 23 Q15418,P07196,P04350,P52292,P68371,Q13885,P54619 7
Formation of tubulin folding intermediates by cct tric 0.3732032978906245 0.2729751444435522 0.7848723220791958 1.0 1.0 13 P50991,P04350,Q9BVA1,P68371,Q13885 5
Collagen biosynthesis and modifying enzymes 0.3839621523608718 0.2726979706081181 0.7850853948224277 1.0 1.0 10 O15460,P07237,P13674,Q32P28 4
Mitochondrial biogenesis 0.3080454480062097 0.2715139496696833 0.785995772247428 1.0 1.0 33 Q13505,Q5XKP0,Q9NX63,Q9BUR5,O75964,P56385,P24539,O75431,Q6UXV4,P54619 10
Copii mediated vesicle transport 0.3093031401605725 0.2636980389237414 0.7920126067775519 1.0 1.0 27 Q12907,Q13190,Q15363,O75396,Q8IUR0,O95487 6
Signaling by flt3 fusion proteins 0.4498514087221418 0.2597933465512891 0.795023183474552 1.0 1.0 4 Q01082,P62993 2
Lysosome vesicle biogenesis 0.3686113437254424 0.2514680597939364 0.801452253521344 1.0 1.0 13 Q9BXS5,P09497,P50570,O43633,P15586,P20645 6
Methionine salvage pathway 0.4858735706362125 0.2507367847721358 0.8020176187976842 1.0 1.0 3 Q13126 1
Fcgamma receptor fcgr dependent phagocytosis 0.3101910136989415 0.2499855083047984 0.8025985556074389 1.0 1.0 23 Q96F07,Q9UQB8,Q8IV08 3
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.4458858413639761 0.2488110850676786 0.8035069160675317 1.0 1.0 4 O14654,Q06124,P62993 3
Signalling to ras 0.4451445515196523 0.2467799394954734 0.8050785363798454 1.0 1.0 4 P11233,P11234,P62993 3
Potential therapeutics for sars 0.3062477301533527 0.2426644482055318 0.8082653505494095 1.0 1.0 34 Q99720,P21964,P07437,P62942,P05023 5
Recycling of eif2 gdp 0.3821337867535962 0.2425922978095806 0.8083212484686484 1.0 1.0 7 Q9NR50 1
G alpha q signalling events 0.3786777279723149 0.2410828927038607 0.8094908714400557 1.0 1.0 9 Q15418,Q8N2K0,P62993 3
Mitotic g1 phase and g1 s transition 0.3551598380419838 0.2318203970781618 0.8166775139831572 1.0 1.0 64 P49721,Q99436,Q9Y619,O75832,P20618,P31749,O75419,O00231,P28072,P28074,P60900,P33991,Q14566,P28070,P61289 15
Nicotinamide salvaging 0.4749837735399391 0.2241791638690625 0.822617895715315 1.0 1.0 3 P43490 1
Regulation of tp53 activity through methylation 0.6551851851851858 0.219750539556934 0.8260654417012887 1.0 1.0 2 O14744 1
G2 m checkpoints 0.3678701473544732 0.2192712060421821 0.8264387903711259 1.0 1.0 73 P49721,Q99436,O75832,P20618,Q9UQ84,O75419,P28072,P28074,P60900,P33991,Q14566,O96028,P28070,P61289 14
Bile acid and bile salt metabolism 0.4037787558046412 0.2128398832921511 0.8314518540336955 1.0 1.0 5 Q9H4L5 1
Synthesis of bile acids and bile salts 0.4037787558046412 0.2128398832921511 0.8314518540336955 1.0 1.0 5 Q9H4L5 1
Nephrin family interactions 0.3736549165120564 0.2119371184043122 0.8321560920067577 1.0 1.0 7 Q13813,P46940,O14936,Q9Y5K6,Q01082,O43707 6
Mhc class ii antigen presentation 0.3354862378377835 0.2057021816836012 0.8370235542685398 1.0 1.0 54 Q14203,O15020,Q9UJW0,O75935,P10619,P52732,Q9BXS5,O95487,P04350,Q9H0H5,Q99538,Q13561,P50570,Q9BVA1,P68371,Q13885,Q9UQ16 17
Degradation of the extracellular matrix 0.371795602610023 0.2053611838552012 0.8372899447253763 1.0 1.0 7 Q92542 1
Signaling by hedgehog 0.3369055976360408 0.2039185238677073 0.8384171692657967 1.0 1.0 55 P49721,Q99436,O75832,P20618,O43242,O00231,P28072,P28074,P60900,P07237,Q9UBV2,Q13885,P68371,P28070,P61289 15
Hedgehog off state 0.3285887768336817 0.2036592615650479 0.8386197794765373 1.0 1.0 50 P49721,Q99436,O75832,P20618,O43242,P28072,O00231,P28074,P60900,P68371,Q13885,P28070,P61289 13
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3685164793899214 0.2016761271705081 0.8401699268617315 1.0 1.0 9 P30260,Q96DE5,Q9UJX4 3
Apc cdc20 mediated degradation of nek2a 0.3685164793899214 0.2016761271705081 0.8401699268617315 1.0 1.0 9 P30260,Q96DE5,Q9UJX4 3
Flt3 signaling in disease 0.3969508848896229 0.1928268510246845 0.8470945740322919 1.0 1.0 5 P62993,Q01082 2
Met activates ras signaling 0.4602097522472178 0.1906123545026876 0.8488293101725866 1.0 1.0 3 P62993 1
Rho gtpases activate iqgaps 0.3598585971430049 0.1841844907025071 0.8538687259641204 1.0 1.0 11 Q13885,P04350,P68371 3
Cd28 co stimulation 0.3654282922207965 0.1830009894607869 0.8547972422512764 1.0 1.0 6 P31749,P42345 2
Regulation of runx2 expression and activity 0.312026347083975 0.1793321554109627 0.8576768997281268 1.0 1.0 42 P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289 8
Nuclear envelope ne reassembly 0.323208913100421 0.1747869880506957 0.8612470129763861 1.0 1.0 49 P30153,P42167,Q9BTX1,Q8NFH4,Q7Z3B4,Q86Y07,P04350,P06493,Q8N1F7,P68371,Q13885,Q9Y2U8,Q8NFH5,P50402,Q9BVA1,Q86XL3,Q14739,Q92973,O43633,Q9BVL2 20
Tp53 regulates metabolic genes 0.2938642257146237 0.1735153539365471 0.8622463602337878 1.0 1.0 30 O94925,P31749,Q9NQ88,P00403,P20674,P13073,O75880,P54619 8
Aggrephagy 0.3470176648843439 0.1711576464781822 0.8640998092174916 1.0 1.0 14 P04350,P07900,P08670,P68371,Q13885 5
Nicotinate metabolism 0.4148908983500759 0.1700468828424739 0.8649732663466252 1.0 1.0 4 P43490 1
Regulation of plk1 activity at g2 m transition 0.2927701001269132 0.1650528497451446 0.8689023843644668 1.0 1.0 30 P07437,O75935,O43805,P04350,P07900,Q13561,Q15691,O94927,P68371 9
Rna polymerase iii transcription termination 0.4125277983691644 0.164581504992844 0.8692733895619185 1.0 1.0 4 P62875,P19388,O14802 3
Rhobtb gtpase cycle 0.294955003492364 0.163997406978041 0.869733185106861 1.0 1.0 28 Q16543,P62995,P07900,P08670,P07910,Q9BT78,Q99832,Q9NYL9,P38159 9
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.3576017638426776 0.1612409308343592 0.8719036447159112 1.0 1.0 9 P50750,Q96PU5 2
Irs mediated signalling 0.4457206372730616 0.1605395332764479 0.872456082406583 1.0 1.0 3 Q06124,P62993 2
Apoptotic factor mediated response 0.3584036664027911 0.1603734331860368 0.8725869159776554 1.0 1.0 6 O60443 1
Synthesis of pips at the er membrane 0.6214814814814837 0.1603448001985835 0.8726094699359526 1.0 1.0 2 Q9NTJ5 1
P38mapk events 0.44497962208225 0.1590786656698428 0.8736068964972876 1.0 1.0 3 P11233,P11234 2
Diseases of mitotic cell cycle 0.3535410252937895 0.1515635158409965 0.8795312110356119 1.0 1.0 10 P30260,Q96DE5,Q9UJX4 3
Tnfr2 non canonical nf kb pathway 0.3047951349694354 0.1494907716568046 0.8811663906988199 1.0 1.0 40 P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289 8
Dectin 1 mediated noncanonical nf kb signaling 0.3047951349694353 0.149490771656804 0.8811663906988203 1.0 1.0 40 P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289 8
Protein folding 0.2945344830535127 0.1494731516374927 0.8811802932440775 1.0 1.0 34 P50991,P04062,Q9Y2T2,P04350,Q9BVA1,P68371,Q13885,Q99471,O15212 9
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.2899045667233744 0.1430518642188221 0.8862492206365928 1.0 1.0 30 Q9UJW0,O75935,P04350,P07900,Q13561,Q9BVA1,P68371,Q13885 8
Ctla4 inhibitory signaling 0.3765938179430496 0.1373419168929278 0.8907605394484797 1.0 1.0 5 P31749 1
Signaling by hippo 0.3505192878338281 0.1359689424359629 0.8918458332551022 1.0 1.0 6 P31946,Q13043,Q4VCS5,P62258,Q07157 5
Neurotransmitter release cycle 0.3500501184228537 0.1345507861909557 0.8929670545785804 1.0 1.0 6 Q96QD8 1
Tp53 regulates transcription of death receptors and ligands 0.6007407407407439 0.1296068282182423 0.8968775006821503 1.0 1.0 2 P04637 1
Recycling pathway of l1 0.2921724842365402 0.1290679202943834 0.8973039055486862 1.0 1.0 22 Q15418,P04350,P50570,Q9BVA1,P68371,Q13885,Q9UQ16 7
P75 ntr receptor mediated signalling 0.3405251148349897 0.1279348059902627 0.8982005661654173 1.0 1.0 13 Q9NQC3 1
Regulated necrosis 0.3172763551449177 0.1201234998227095 0.9043853170121384 1.0 1.0 18 Q16543,P41440,P07900,O60443,O43633,Q8WUM4 6
Synthesis of dna 0.3514332514103226 0.1190144623444251 0.9052638979257486 1.0 1.0 71 P49721,Q99436,Q9Y619,O75832,P20618,P41440,Q9UJX4,O75419,O00231,P28072,P28074,P60900,Q96DE5,P33991,Q14566,P28070,P61289 17
Sting mediated induction of host immune responses 0.3445845697329386 0.1183188640132093 0.9058150110649748 1.0 1.0 6 P12956,P19474,P78527,P49959,Q9UJV9 5
Pkmts methylate histone lysines 0.3253706042251609 0.1105805543713189 0.9119489682654502 1.0 1.0 16 Q03164 1
Methylation 0.3416964007913537 0.1099592906993874 0.912441660391336 1.0 1.0 6 P21964 1
Ripk1 mediated regulated necrosis 0.3405972860778701 0.1098899532924602 0.9124966503983988 1.0 1.0 11 Q16543,P41440,O75955,P07900,O00560,Q8WUM4 6
Degradation of beta catenin by the destruction complex 0.3075625813536511 0.1063492928979454 0.9153052232337102 1.0 1.0 45 P49721,Q99436,O75832,P20618,P28072,O00231,P28074,P60900,P30154,P28070,P61289 11
Pcp ce pathway 0.3105982795372534 0.1040982645307242 0.917091368080974 1.0 1.0 47 P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289 8
Death receptor signalling 0.3140933968449652 0.1037976872342182 0.9173299018763534 1.0 1.0 18 Q9NQC3,Q8TCT8 2
Sulfur amino acid metabolism 0.3403804502961686 0.101835270590796 0.9188874292852078 1.0 1.0 9 Q9UBX3,Q13126 2
Hur elavl1 binds and stabilizes mrna 0.3611420096403448 0.0996586665083292 0.920615316463685 1.0 1.0 5 Q15717,P39687,P35658,Q01105 4
Senescence associated secretory phenotype sasp 0.3268767629672173 0.0988325622056715 0.9212712141515556 1.0 1.0 15 P30260,Q15418,Q9UJX3,Q9UJX4,P51812,Q96DE5 6
Cellular response to chemical stress 0.3468779321495527 0.0970951062350578 0.9226508671592542 1.0 1.0 70 P33527,P49721,Q99436,Q8TCT9,P20618,O75832,O00231,P28072,P28074,P60900,P13073,P09601,P00403,P07237,P30519,P28070,P61289 17
Rsk activation 0.3763901094248166 0.0911220507893765 0.9273956115342628 1.0 1.0 4 Q15418 1
Nuclear receptor transcription pathway 0.5670370370370417 0.0889202985002882 0.9291452515814064 1.0 1.0 2 Q9UHY1 1
Dissolution of fibrin clot 0.3994071878473516 0.0838058149961509 0.933210824589158 1.0 1.0 3 P60903,P35237 2
Nuclear pore complex npc disassembly 0.2823299546959419 0.0731223340862934 0.9417087692 1.0 1.0 28 Q8NFH4,Q7Z3B4,Q8NFH5,Q92621,Q99567,P35658,P55735,P06493,Q8N1F7,Q9BVL2,Q9BTX1 11
Organelle biogenesis and maintenance 0.3666095334239652 0.0726034543898101 0.942121677771992 1.0 1.0 85 Q14203,P56134,P50991,O43805,P07900,Q9BUR5,O94927,O43924,A6NIH7,Q6UXV4,P07437,O75935,Q13505,P04350,Q13561,P68371,Q13885,P53350,P54619,Q10713,Q9NX63,Q9BVA1,P56385,Q16891,Q92973,Q7Z4L5,Q15691,Q5XKP0,O75964,A0AVF1,P24539,O75431 32
Ncam signaling for neurite out growth 0.3219075264286125 0.0568987565746951 0.9546258448197767 1.0 1.0 6 O15020,P62993 2
Pd 1 signaling 0.5303703703703683 0.0567493262118274 0.9547448806622107 1.0 1.0 2 P41240 1
Biological oxidations 0.2891129404921569 0.0566245948991841 0.9548442420778758 1.0 1.0 38 P16435,O43169,Q9NUJ1,Q9H2H9,P21964,Q16850,Q8TB61 7
Auf1 hnrnp d0 binds and destabilizes mrna 0.2938978259604513 0.0546601803978155 0.9564091933487004 1.0 1.0 41 P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289 8
Apc c mediated degradation of cell cycle proteins 0.3104728510666063 0.0544663922103489 0.956563583957994 1.0 1.0 51 P49721,Q99436,O75832,P20618,Q9UJX4,O00231,P28072,P28074,P60900,Q96DE5,P28070,P61289 12
Rho gtpases activate wasps and waves 0.3184914209228799 0.0510078482858775 0.959319266663332 1.0 1.0 14 Q96F07,Q9UQB8 2
Formation of tc ner pre incision complex 0.2793757887909888 0.0468157009118879 0.962660115236076 1.0 1.0 26 Q16531 1
Synthesis of pips at the golgi membrane 0.3181287361265418 0.0370569958746017 0.970439560779078 1.0 1.0 8 Q10713,Q9BTU6 2
Signaling by leptin 0.4951851851851916 0.0360284296375621 0.9712596900924166 1.0 1.0 2 Q06124 1
Interleukin 37 signaling 0.4951851851851916 0.0360284296375621 0.9712596900924166 1.0 1.0 2 Q06124 1
Activation of smo 0.4792592592592551 0.02934848458854 0.976586658428176 1.0 1.0 2 P48729 1
Smooth muscle contraction 0.3162393162393119 0.027054630073676 0.9784161614573552 1.0 1.0 11 P18206,P04083,P67936,Q13177,Q9Y490,P09493,Q05682,P07355,P06753,P60660 10
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.329132690882132 0.0240592791646197 0.9808053244312174 1.0 1.0 4 P30154,P30153,P49643 3
Dna replication initiation 0.3290107447202636 0.0196113669081414 0.984353396096388 1.0 1.0 3 Q07864,P49643 2
Cd163 mediating an anti inflammatory response 0.4448148148148221 0.0193826726724864 0.9845358330172505 1.0 1.0 2 P35579 1
Signaling by erbb2 0.3110378394051266 0.0186990805594997 0.9850811617346906 1.0 1.0 8 P31749,Q16543,P07900 3
Miro gtpase cycle 0.3221459682737674 0.0168041136959448 0.986592888106436 1.0 1.0 4 Q8IWA4 1
Ngf stimulated transcription 0.3544444444444407 0.0103811849040366 0.9917171616146984 1.0 1.0 2 P50570 1
Ns1 mediated effects on host pathways 0.2742234142413744 0.0100456849415129 0.991984837892101 1.0 1.0 33 Q8NFH4,Q7Z3B4,Q8NFH5,Q86U42,Q92621,P35658,P52292,P55735,Q8N1F7,Q9BVL2,Q9BTX1 11
Reactions specific to the complex n glycan synthesis pathway 0.338888888888888 0.0100163225222138 0.9920082645344904 1.0 1.0 2 P04066 1
N glycan antennae elongation in the medial trans golgi 0.338888888888888 0.0100163225222138 0.9920082645344904 1.0 1.0 2 P04066 1
Pyroptosis 0.3041127732888067 0.008231234047538 0.9934324995987416 1.0 1.0 7 O60443 1
Initiation of nuclear envelope ne reformation 0.2975180841340489 0.0049194353030556 0.9960748743557216 1.0 1.0 17 Q86XL3,P30153,Q86Y07,P42167,Q14739,P50402,P06493,Q9Y2U8 8
Vegfr2 mediated vascular permeability 0.3073171690868391 0.0047979128641021 0.9961718340890372 1.0 1.0 9 P31749,P07900 2
Aryl hydrocarbon receptor signalling 0.290848462393474 0.0047555206920634 0.9962056577627232 1.0 1.0 3 P08238,O00170 2
Dap12 interactions 0.3071946255555544 0.0033712014301551 0.9973101755224992 1.0 1.0 4 P10321 1
Suppression of apoptosis 0.2782512041496803 0.0018722305239396 0.9985061770433878 1.0 1.0 3 P28482,P23246 2
Cytochrome c mediated apoptotic response 0.2782512041496792 0.0018722305239393 0.998506177043388 1.0 1.0 3 P28482,Q9NR28 2
Formation of apoptosome 0.2782512041496792 0.0018722305239393 0.998506177043388 1.0 1.0 3 P28482,Q9NR28 2
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