Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Sphingolipid metabolism	0.7478723459454395	3.3876699408270996	0.0007048903400694	0.6164494115383049	0.4789729860772165	24	P51648,A0FGR8,P16278,P04062,P10619,P06280,O95470,Q96G23,P07602,P17900,Q13510,P06865,Q06136	13
Slc mediated transmembrane transport	0.7097069785297524	3.0756695558459626	0.0021003047220868	0.942577311614106	0.5286366263530318	22	Q8NEW0,P11166,Q70HW3,Q9H2H9,P04920,O00400,P35613,Q9UBX3,P12236,P53985,Q8TB61,Q96QD8	12
Glycerophospholipid biosynthesis	0.6455428644966617	2.853141872984268	0.0043289290388319	0.9972489840750977	0.7353768204715818	27	Q9NPH0,Q8NF37,Q9NQZ5,Q6P1A2,Q8IV08,P35790,P48651	7
Ion channel transport	0.6237717307936962	2.7029045107951792	0.0068736490009611	0.9999150579451774	0.8492080902096488	27	Q96PU5,Q9Y487,Q93050,P16615,P05023,P98194,Q9C0H2,Q9HD20,P51790,P51798,P21281	11
Glycosphingolipid metabolism	0.784385229202635	2.6275148526834595	0.0086011086885526	0.9999920271266018	0.8740439357402792	15	A0FGR8,P16278,P04062,P10619,P06280,P07602,P17900,Q13510,P06865	9
Mitochondrial protein import	0.585931272922023	2.564777300516049	0.0103242045387434	0.9999992502482796	0.8740439357402792	34	Q9NS69,Q99595,Q15388,O14925,Q10713,Q8N4H5,Q13505,Q5JRX3,P21796,Q9NX63,Q9Y5J7,O75431	12
Synthesis of pa	0.861483294144259	2.457936929559683	0.0139737712563241	0.9999999950520264	0.8740439357402792	8	Q9NPH0	1
Rac2 gtpase cycle	0.5546844406138194	2.3585735617961685	0.0183453234153889	0.9999999999881988	0.8740439357402792	32	P02786,Q86XL3,Q13505,Q14739,Q9H0H5,O15173,Q7L576	7
Cholesterol biosynthesis	0.7296857075962504	2.343954667193022	0.0190804903715753	0.9999999999957366	0.8740439357402792	15	Q9BWD1,Q14739,Q16850,Q14534,Q15392,P48449,P37268,Q9UBM7	8
Glycosaminoglycan metabolism	0.7742833906384516	2.3244237121341196	0.0201027959096378	0.9999999999989664	0.8740439357402792	12	P16278,P54802,O43505,Q8TB61,P15586,P06865	6
Stimuli sensing channels	0.8283699963024092	2.2594949015579093	0.0238526170962334	0.9999999999999944	0.8740439357402792	7	P51790,Q96PU5,Q9C0H2	3
Metabolism of porphyrins	0.8154292304445441	2.2569042869291653	0.0240140561224828	0.9999999999999954	0.8740439357402792	8	Q7KZN9,P22830,P30519,P09601	4
Phospholipid metabolism	0.5562092408800446	2.242889811929701	0.0249039209083388	0.9999999999999988	0.8740439357402792	40	Q9NPH0,Q8NF37,O95674,Q9BTU6,Q8NCC3,Q9NQZ5,Q6P1A2,Q8IV08,P35790,P48651	10
Pink1 prkn mediated mitophagy	0.8090294065465762	2.175590532587569	0.0295858918922888	1.0	0.8740439357402792	7	Q9NS69,P21796	2
Selective autophagy	0.5406138845683991	2.139638305204042	0.0323840084631152	1.0	0.8740439357402792	28	Q9NS69,Q15388,Q8N4H5,P50542,P04350,P21796,P07900,P08670,P68371,Q13885,Q8IWA4,P54619	12
Mitochondrial calcium ion transport	0.686537899250964	2.113265230812678	0.0345780728871019	1.0	0.8740439357402792	15	Q9BPX6,Q9Y277,P21796,P45880,O95202,Q8WWC4,Q99623	7
Synthesis of pc	0.8534965866506625	2.05254524315634	0.040116702829666	1.0	0.9082674844982191	5	Q9NQZ5,P35790	2
Keratan sulfate keratin metabolism	0.8500419268979338	2.038396061390278	0.0415103398737135	1.0	0.9082674844982191	5	P06865,P16278,O43505	3
Mitophagy	0.7392626069397735	2.022751713765315	0.0430987522592531	1.0	0.9082674844982191	10	Q9NS69,P21796	2
Copi dependent golgi to er retrograde traffic	0.5344775846911038	1.994338027260667	0.0461151261445011	1.0	0.9082674844982191	45	Q86Y91,O14579,Q9P2W9,P24390,P04350,Q9BVK6,O75396,Q9H0H5,O15260,Q15363,P49755,Q9Y3B3,P68371,Q9BVA1,Q13885,Q8N6T3,P52732	17
Heme degradation	0.8374178331451301	1.9865128502551064	0.0469764074116541	1.0	0.9101162151381792	5	P30519,P09601	2
Rac3 gtpase cycle	0.507087866029884	1.957801313898634	0.0502533312012831	1.0	0.926378208667791	30	P02786,Q9UQB8,Q14739,Q9H0H5,O15173,Q7L576	6
Vitamin d calciferol metabolism	0.9329381252315684	1.9140507655547505	0.0556136695298183	1.0	0.926378208667791	3	Q99538,P04062	2
Transport of inorganic cations anions and amino acids oligopeptides	0.7268830404641193	1.9075968088364637	0.0564433479185972	1.0	0.926378208667791	9	Q9UBX3,P04920,Q70HW3,Q9H2H9	4
Autophagy	0.5078866014139176	1.89179494232644	0.0585183074411665	1.0	0.926378208667791	38	Q9NS69,Q15388,Q8N4H5,Q9NT62,P50542,P04350,P21796,P07900,P08670,O43633,P42345,Q13885,Q8IWA4,P68371,P54619	15
Activation of ampk downstream of nmdars	0.7538615218010174	1.8872555474126311	0.0591259622863586	1.0	0.926378208667791	6	Q13885,P54619,P04350,P68371	4
Cristae formation	0.5658725348186731	1.8846113565498244	0.0594823279272966	1.0	0.926378208667791	20	Q13505,Q5XKP0,Q9BUR5,Q9NX63,O75964,P56385,P24539,O75431,Q6UXV4	9
Mucopolysaccharidoses	0.8724981467753965	1.8786921919168065	0.060286534578624	1.0	0.926378208667791	4	P15586,P16278,P54802	3
Rhog gtpase cycle	0.4977044107135751	1.8741247273058856	0.0609132358746065	1.0	0.926378208667791	34	P02786,Q13190,Q86XL3,Q14739,O95202,O15173,Q7L576	7
Heparan sulfate heparin hs gag metabolism	0.8663397296424549	1.8543851278398027	0.0636840809693308	1.0	0.926378208667791	4	P16278,P54802	2
Peptide ligand binding receptors	0.7405027021857972	1.8282328508763663	0.0675146127032404	1.0	0.926378208667791	6	P42892,P07602,Q9NZJ7	3
Class a 1 rhodopsin like receptors	0.7405027021857972	1.8282328508763663	0.0675146127032404	1.0	0.926378208667791	6	P42892,P07602,Q9NZJ7	3
Transport of bile salts and organic acids metal ions and amine compounds	0.9103371619118216	1.8251526953313513	0.0679779900397241	1.0	0.926378208667791	3	Q8NEW0,P35613	2
Diseases of carbohydrate metabolism	0.726824303828171	1.809696733049592	0.070342829437326	1.0	0.926378208667791	7	P15586,P10253,P54802,P16278	4
Response to elevated platelet cytosolic ca2	0.5014624228671198	1.8057793790715564	0.070952807721649	1.0	0.926378208667791	27	Q9NUQ9,Q08380,P07602,Q9NZJ7,Q8NBX0,Q9NTK5,O43852,O94919,Q6UXV4	9
Rhoa gtpase cycle	0.4966106715285386	1.800220542273438	0.0718258214425064	1.0	0.926378208667791	38	P02786,Q13190,Q14739,P41440,Q9H0H5,O15173,Q8NBN3,P30519	8
Class i peroxisomal membrane protein import	0.7125477623032803	1.7899968246504734	0.0734544218687858	1.0	0.926378208667791	8	P51648,Q9NR77,P40855	3
Ire1alpha activates chaperones	0.5329994138930831	1.7780427787923778	0.0753968292143971	1.0	0.926378208667791	21	Q8N6T3,Q9NWM8,P35611,P43307,O95070,P61421,Q13217,Q9Y5M8,O14773	9
Ras processing	0.7836088054076193	1.7623114806504103	0.0780166852066268	1.0	0.926378208667791	5	O43924	1
Gamma carboxylation hypusine formation and arylsulfatase activation	0.6929403666218785	1.7463847978463514	0.0807441097587249	1.0	0.926378208667791	9	Q9BU89,O60725,P49366	3
Pre notch processing in golgi	0.8903297517599142	1.7459951258619015	0.0808117987995695	1.0	0.926378208667791	3	Q15363,Q9UBV2	2
Keratan sulfate degradation	0.8354198845933065	1.7315939452363216	0.0833458850151873	1.0	0.926378208667791	4	P16278,P06865	2
Synaptic adhesion like molecules	0.7149315899816657	1.7142577323646846	0.0864814021559157	1.0	0.926378208667791	6	O95197	1
Unwinding of dna	0.667572236606536	1.674597285073386	0.0940132723169808	1.0	0.926378208667791	10	Q14566,P33991	2
Hs gag degradation	0.8721748795850367	1.6738288946430215	0.0941642318689872	1.0	0.926378208667791	3	P16278,P54802	2
Sphingolipid de novo biosynthesis	0.6762551113892397	1.6661773921341008	0.0956780875033502	1.0	0.926378208667791	9	P51648,O95470,Q96G23,O15269,Q06136	5
Abc family proteins mediated transport	0.5035846666209134	1.653391765816111	0.0982511575896538	1.0	0.926378208667791	51	O75477,P33527,P49721,Q99436,O75832,P20618,O75027,O00231,P28072,P28074,O94905,P60900,Q9UBV2,Q9BUN8,P08183,P40855,P28070,P61289	18
Peptide hormone metabolism	0.6436766905122757	1.6087875364692827	0.1076628070936875	1.0	0.9505179260777646	11	P67812	1
Activation of the pre replicative complex	0.6321770030668163	1.6069310888014223	0.1080694856864097	1.0	0.9505179260777646	12	O75419,Q14566,P33991	3
Gap junction assembly	0.7441891201665902	1.5951607373437369	0.1106762961910332	1.0	0.9505179260777646	5	Q13885,P04350,P68371	3
Transport of connexons to the plasma membrane	0.7441891201665902	1.5951607373437369	0.1106762961910332	1.0	0.9505179260777646	5	Q13885,P04350,P68371	3
Ros and rns production in phagocytes	0.6533734909174823	1.5552192603781831	0.1198938587221911	1.0	0.9505179260777646	9	Q9Y487	1
Gpcr ligand binding	0.6486402553543307	1.5321351519199404	0.1254890869289164	1.0	0.9505179260777646	9	P42892,P07602,Q9NZJ7	3
Intra golgi traffic	0.6475041153154424	1.5265877535919978	0.1268635541572338	1.0	0.9505179260777646	9	O00461,Q13190,O95249	3
Striated muscle contraction	0.7259072249906274	1.5169144405258428	0.1292882872175127	1.0	0.9505179260777646	5	Q9NYL9,P08670,P09493	3
Signaling by erbb4	0.6628338278931566	1.4783186371696555	0.1393225115230776	1.0	0.9505179260777646	6	P49768,P16949,Q92542,P62993,P61201	5
Kinesins	0.5171373078116892	1.459224097962311	0.144503438284631	1.0	0.9505179260777646	19	Q86Y91,P04350,Q9H0H5,P68371,Q13885,P52732	6
Protein localization	0.5101521990177034	1.4570359859414028	0.145106446983422	1.0	0.9505179260777646	68	Q9NS69,Q99595,P51648,O15254,Q15067,P21796,O14925,Q15388,P46379,Q8N4H5,O00116,Q13505,Q9BY49,Q13011,P40855,O75381,Q13190,P50402,Q9NX63,P09601,Q9NR77,O75431	22
Cargo concentration in the er	0.5918934519404718	1.4516775054704212	0.1465912968248954	1.0	0.9505179260777646	13	Q12907,Q13190,Q15363,O75396,Q96PC5,O95487	6
Nr1h2 and nr1h3 mediated signaling	0.7062865293869095	1.4325037269635368	0.151999712262056	1.0	0.9505179260777646	5	Q8NB78,Q9HCE1	2
Transferrin endocytosis and recycling	0.6086103785950528	1.4285415619477568	0.1531360407162165	1.0	0.9505179260777646	11	P02786,Q9Y487,Q93050,Q15904,P21281	5
Sialic acid metabolism	0.7601097029147512	1.4280748794578633	0.1532703070782632	1.0	0.9505179260777646	4	P16278	1
Abc transporter disorders	0.4564486748772156	1.4188701698239206	0.1559368704747976	1.0	0.9505179260777646	41	O75477,P49721,Q99436,O75832,P20618,O00231,P28072,P28074,O94905,P60900,Q9UBV2,P28070,P61289	13
Defective cftr causes cystic fibrosis	0.4564486748772155	1.4188701698239206	0.1559368704747976	1.0	0.9505179260777646	41	O75477,P49721,Q99436,O75832,P20618,O00231,P28072,P28074,O94905,P60900,Q9UBV2,P28070,P61289	13
Peroxisomal lipid metabolism	0.6158780496112835	1.416247521831163	0.1567030466726455	1.0	0.9505179260777646	10	P51648,Q15067,O15254	3
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation	0.8054835124120074	1.4066751314594812	0.159523743197699	1.0	0.9505179260777646	3	P31749,P00374	2
O linked glycosylation	0.8048343641945616	1.4040645841425652	0.1602996185539731	1.0	0.9505179260777646	3	O43505	1
O linked glycosylation of mucins	0.8048343641945616	1.4040645841425652	0.1602996185539731	1.0	0.9505179260777646	3	O43505	1
Assembly and cell surface presentation of nmda receptors	0.6109183353466401	1.3911896921137092	0.1641679121700139	1.0	0.9505179260777646	10	P07196,Q13885,P04350,P68371	4
Processing of smdt1	0.610538866779252	1.389270813269918	0.1647504155987396	1.0	0.9505179260777646	10	Q9BPX6,Q10713,Q9UJZ1,Q9Y4W6,Q8WWC4,Q99623	6
Insulin receptor recycling	0.6101871872901103	1.387492245039047	0.1652917142105763	1.0	0.9505179260777646	10	Q9Y487	1
Transport of vitamins nucleosides and related molecules	0.6159082571590512	1.3713954034842408	0.1702517295755741	1.0	0.9505179260777646	9	O00400,Q99808,P12236,P12235,Q8TB61,Q9Y289	6
Intraflagellar transport	0.5957620486045979	1.3618880292997295	0.1732332245747647	1.0	0.9505179260777646	11	P04350,Q7Z4L5,A0AVF1,Q9BVA1,Q13885,P68371	6
Recruitment of numa to mitotic centrosomes	0.4328346613185153	1.3484049906674618	0.1775281596932407	1.0	0.9505179260777646	30	Q14203,P07437,O75935,O43805,P04350,P07900,Q13561,Q15691,O94927,Q9BSJ2,Q9BVA1,P68371,Q13885,P53350	14
Constitutive signaling by overexpressed erbb2	0.7906632085957755	1.3470588869836015	0.1779612678830848	1.0	0.9505179260777646	3	Q16543,P07900	2
Cargo trafficking to the periciliary membrane	0.5132819616482038	1.344965164471735	0.1786364844476093	1.0	0.9505179260777646	18	O43924,A6NIH7	2
Iron uptake and transport	0.5124353399603211	1.3395148841136564	0.1804031122753018	1.0	0.9505179260777646	18	Q93050,P30519,Q9Y487	3
Heme biosynthesis	0.7881841883223826	1.337085021444992	0.1811948858654657	1.0	0.9505179260777646	3	Q7KZN9	1
Recruitment of mitotic centrosome proteins and complexes	0.4432906861686321	1.3217689337146692	0.1862451061599193	1.0	0.9505179260777646	26	Q14203,P07437,O75935,O43805,P04350,P07900,P06493,Q13561,O94927,Q9BSJ2,Q15691,P68371,P62258,P53350	14
Energy dependent regulation of mtor by lkb1 ampk	0.7332914189257518	1.3189424865638546	0.1871883407977912	1.0	0.9505179260777646	4	Q9Y376,P54619	2
Alpha oxidation of phytanate	0.7812716184453822	1.3092747121617154	0.1904413123446833	1.0	0.9505179260777646	3	P51648	1
Diseases of glycosylation	0.5630686906766181	1.293498026171492	0.1958388663000545	1.0	0.9505179260777646	13	P10619,Q9BV10,P16278,O43505	4
Mtor signalling	0.5780786064827472	1.2697086260086774	0.2041884390068786	1.0	0.9774358848839666	11	Q9Y376,P62942,P31749,P42345,P54619	5
Basigin interactions	0.6138229817294135	1.2526898656216376	0.2103185955932951	1.0	0.9926583428919548	6	P35613	1
Copi mediated anterograde transport	0.4471932536429484	1.2460000836885787	0.2127643644590291	1.0	0.9926583428919548	47	Q13190,O75935,O14579,P24390,Q9BVK6,Q15363,Q13561,Q9Y3B3,P68371,O95249	10
Metabolism of fat soluble vitamins	0.7654448678390706	1.2456308861594283	0.2128999377449232	1.0	0.9926583428919548	3	Q8N0U8	1
Regulation of tp53 expression and degradation	0.6053281540375327	1.2445876809336491	0.2132833509641098	1.0	0.9926583428919548	7	P06493,P31749,P30154,P42345	4
Post chaperonin tubulin folding pathway	0.5773273515462685	1.2205195474950967	0.2222679839645778	1.0	1.0	10	P04350,Q99426,Q9BTW9,Q9BUF5,O75347,Q9BVA1,P68371,Q13885	8
Intra golgi and retrograde golgi to er traffic	0.4967570972085739	1.208299097663836	0.2269322354326872	1.0	1.0	78	Q8N2H4,O14579,P24390,Q9Y3B3,O95249,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q8N1B4,Q13885,O00461,P52732,Q86Y91,O95721,Q13190,Q9UJW0,O15260,Q9BVA1,Q8N6T3,Q9P2W9,Q10472,Q15363,Q9H0H5,P49755,P11717,Q6NUQ1	29
Activation of atr in response to replication stress	0.5369702959505812	1.2049767551927473	0.2282122755409663	1.0	1.0	14	O75419,Q14566,P33991	3
Nuclear signaling by erbb4	0.7045959970348548	1.201961705658655	0.2293783652030696	1.0	1.0	4	P16949,P61201,Q92542	3
Ion transport by p type atpases	0.5648137485688511	1.2002874035657594	0.2300277401614048	1.0	1.0	11	Q9HD20,P16615,P05023	3
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux	0.7490782976637099	1.1799177881818488	0.2380329142936377	1.0	1.0	3	Q8NB78	1
Slc transporter disorders	0.4114217384998775	1.1643864757130526	0.2442674258738764	1.0	1.0	33	Q8NFH4,Q7Z3B4,P35613,O00400,P53985,Q8N1F7,Q9BTX1	7
Cilium assembly	0.4443617625104979	1.1451416483970578	0.2521504853552299	1.0	1.0	52	P50991,O43805,P07900,O94927,O43924,A6NIH7,P07437,O75935,P04350,Q13561,P68371,Q13885,P53350,Q10713,Q9BVA1,Q92973,Q7Z4L5,Q15691,A0AVF1	19
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.6381164256581288	1.1370204033530231	0.2555297563243384	1.0	1.0	5	P12236,P05141,P12235,Q99808	4
Regulation of runx3 expression and activity	0.4135684962284384	1.133684430520911	0.256926942817272	1.0	1.0	36	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Signaling by insulin receptor	0.5137402386727533	1.1305249545298337	0.258255089415677	1.0	1.0	15	Q9Y487	1
Golgi to er retrograde transport	0.4636726455978724	1.129973345674289	0.258487456011814	1.0	1.0	64	O14579,P24390,Q9Y3B3,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q13885,P52732,Q86Y91,Q9UJW0,O15260,Q9BVA1,Q8N6T3,Q9P2W9,Q10472,Q9H0H5,Q15363,P49755,Q6NUQ1	22
Carboxyterminal post translational modifications of tubulin	0.5869241173333141	1.1279497632476136	0.2593411359096773	1.0	1.0	6	Q13885,P04350,P68371	3
Peroxisomal protein import	0.4795770875859715	1.126628038278637	0.2598997793915698	1.0	1.0	18	O15254,O00116,Q15067,Q9BY49,Q13011	5
Amino acid transport across the plasma membrane	0.6839381761070538	1.117822305246208	0.2636428931008794	1.0	1.0	4	Q9H2H9	1
Pre notch expression and processing	0.5708457055393568	1.1122665325570391	0.2660235690119485	1.0	1.0	8	Q9UBV2,Q15363	2
Diseases associated with glycosylation precursor biosynthesis	0.5831168297806396	1.110273144881296	0.2668813417402846	1.0	1.0	6	P16278	1
Hedgehog ligand biogenesis	0.4159574049455591	1.1057345916034111	0.268841413053257	1.0	1.0	39	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,Q9UBV2,P07237,P28070,P61289	11
Glutamate neurotransmitter release cycle	0.7304281183646087	1.1052672478839722	0.2690438052757933	1.0	1.0	3	Q96QD8	1
Metabolism of polyamines	0.4130419987463842	1.0966891061451898	0.2727773202197889	1.0	1.0	38	P49721,Q9H2H9,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	10
Cdt1 association with the cdc6 orc origin complex	0.4075268710152185	1.0651640623736809	0.2868016932890764	1.0	1.0	37	P49721,Q99436,Q9Y619,O75832,P20618,P28072,P28074,P60900,P28070,P61289	10
Anchoring of the basal body to the plasma membrane	0.4097898974188424	1.0533524098312794	0.292179506897692	1.0	1.0	26	Q14203,P07437,O75935,O43805,P04350,P07900,P06493,Q13561,O94927,Q15691,P68371,P62258,P53350	13
Rac1 gtpase cycle	0.4023457715845296	1.02025783394639	0.3076061954908284	1.0	1.0	37	P02786,Q9UQB8,Q14739,Q9H0H5,Q96F07,Q7L576	6
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	0.5044745433905613	1.019146328638804	0.3081335025272298	1.0	1.0	14	Q13217,O43852,Q02818,Q07065,P07237	5
Sema4d induced cell migration and growth cone collapse	0.6106785317018879	1.0179957758674485	0.3086799635217354	1.0	1.0	5	P35579,P35580,Q7Z406,Q13464	4
Epha mediated growth cone collapse	0.6106785317018879	1.0179957758674485	0.3086799635217354	1.0	1.0	5	P35579,P35580,Q7Z406,Q13464	4
Aurka activation by tpx2	0.4043173358017022	1.0091735253870635	0.3128914211090627	1.0	1.0	26	Q14203,P07437,O75935,O43805,P04350,P07900,P06493,Q13561,O94927,Q15691,P68371,P62258,P53350	13
Conversion from apc c cdc20 to apc c cdh1 in late anaphase	0.555141527478435	1.0063091534805622	0.314266878667254	1.0	1.0	7	P30260,Q96DE5,Q9UJX3,Q9UJX4	4
Notch4 activation and transmission of signal to the nucleus	0.7043349388662568	1.001503389272973	0.3165835023767012	1.0	1.0	3	Q92542,P63104	2
Noncanonical activation of notch3	0.7043349388662568	1.001503389272973	0.3165835023767012	1.0	1.0	3	Q92542,P67809	2
Acyl chain remodelling of pc	0.9218518518518536	1.00057297281517	0.3170333020069447	1.0	1.0	2	Q8NF37	1
Dna damage recognition in gg ner	0.4711349272692818	0.99992985278304	0.3173444561993845	1.0	1.0	17	Q16531	1
Endosomal vacuolar pathway	0.7035686526481126	0.9984720041062968	0.3180505333559571	1.0	1.0	3	Q9UIQ6	1
Orc1 removal from chromatin	0.4160912102532405	0.996360168385317	0.3190751789603954	1.0	1.0	46	P49721,Q99436,Q9Y619,O75832,P20618,P28072,P28074,P60900,P33991,Q14566,P28070,P61289	12
Cytochrome p450 arranged by substrate type	0.7027877298705805	0.995383801943152	0.3195496336442729	1.0	1.0	3	Q16850	1
Cooperation of prefoldin and tric cct in actin and tubulin folding	0.470193153289279	0.9939892790830696	0.3202280869041856	1.0	1.0	17	P50991,P04350,Q9UHV9,Q9BVA1,P68371,Q13885,Q99471,O15212	8
Rhoc gtpase cycle	0.4051459017168517	0.9804687861916886	0.3268547700476032	1.0	1.0	24	P02786,Q14739,P41440,Q9H0H5	4
Metabolism of cofactors	0.6498112375042447	0.9794974565869778	0.3273342447075538	1.0	1.0	4	P31749,P00374	2
Signaling by notch4	0.4066913542176739	0.9623282305127218	0.3358847524634765	1.0	1.0	43	P49721,Q99436,O75832,P20618,P31749,P28072,Q92542,P28074,P60900,P28070,P61289	11
Proton coupled monocarboxylate transport	0.9100000000000006	0.9588765272873208	0.3376209509436094	1.0	1.0	2	P35613	1
Runx1 regulates transcription of genes involved in differentiation of hscs	0.3986563937924801	0.940244257222786	0.3470922851285889	1.0	1.0	40	P49721,Q99436,P20618,Q03164,P28072,P28074,P60900,P28070,P61289	9
Degradation of axin	0.3905679425376534	0.9340292958791848	0.3502887813767015	1.0	1.0	36	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Cross presentation of soluble exogenous antigens endosomes	0.3905679425376534	0.9340292958791848	0.3502887813767015	1.0	1.0	36	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Transport of small molecules	0.5625614452183876	0.930116111513749	0.3523109697120954	1.0	1.0	147	Q9BPX6,Q70HW3,O00400,Q8N4V1,O75027,P38571,P21796,P45880,O00231,Q9C0H2,Q9UBV2,Q8TB61,Q9BUN8,Q99797,P30519,P61289,Q99623,P49721,P11166,Q9Y487,O15439,Q93050,Q9UJZ1,P20618,P16615,P61916,P28072,Q8WWC4,O94905,P28074,P60900,Q9HD20,P51790,P40855,O75477,P02786,O15118,Q9H2H9,Q99436,O75832,Q10713,Q8WTV0,P12236,P08183,P09601,P21281,Q8NEW0,P33527,Q96PU5,P04920,Q9Y277,P35613,Q9UBX3,P05023,P35611,O43242,O95202,P98194,Q15904,P53985,P51798,Q96QD8,P07237,P28070	64
Hyaluronan uptake and degradation	0.5897937133765949	0.9278340682743312	0.3534936490124556	1.0	1.0	5	P06865	1
Hyaluronan metabolism	0.5897937133765949	0.9278340682743312	0.3534936490124556	1.0	1.0	5	P06865	1
Protein protein interactions at synapses	0.504221846484684	0.9220770906039132	0.3564883657926918	1.0	1.0	12	O95197	1
Phase i functionalization of compounds	0.4938641471284494	0.9095723824503916	0.3630480689288715	1.0	1.0	13	O43169,Q16850	2
Switching of origins to a post replicative state	0.4175314241694913	0.902048824209552	0.3670309322808998	1.0	1.0	53	P49721,Q99436,Q9Y619,O75832,P20618,Q9UJX4,O00231,P28072,P28074,P60900,Q96DE5,P33991,Q14566,P28070,P61289	15
Degradation of dvl	0.3886319423056957	0.9010884278158594	0.3675413052425433	1.0	1.0	37	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Stabilization of p53	0.3880558630520152	0.8960759187117496	0.3702122175270288	1.0	1.0	37	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
G1 s dna damage checkpoints	0.3880558630520152	0.8960759187117496	0.3702122175270288	1.0	1.0	37	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Flt3 signaling	0.6277307772384855	0.890857557747663	0.3730055920554227	1.0	1.0	4	P31749	1
Synthesis of pg	0.8896296296296329	0.8879611781707007	0.3745616343356022	1.0	1.0	2	Q8IV08	1
Regulation of ras by gaps	0.3885297487135273	0.8842130806036127	0.3765811984778622	1.0	1.0	38	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Interleukin 4 and interleukin 13 signaling	0.4877855315719739	0.8758613866780326	0.3811053932446056	1.0	1.0	13	P08670,P31749,P09601	3
Downstream signaling events of b cell receptor bcr	0.3888261638114282	0.8708900956172616	0.383814165222835	1.0	1.0	39	P49721,Q99436,P62942,O75832,P20618,P28072,P28074,P60900,P28070,P61289	10
Complex i biogenesis	0.3867950295103917	0.8674328034301352	0.3857049148729159	1.0	1.0	26	Q9P0J0,Q9Y6M9,Q86Y39,O96000,O43676	5
Plasma lipoprotein clearance	0.4934607004463008	0.864111565071607	0.3875266064505303	1.0	1.0	12	Q8WTV0,O15118	2
Transcriptional regulation by ventx	0.507186179946537	0.8620854464333326	0.3886404994101913	1.0	1.0	10	P30260,Q9UJX3,Q9UJX4,Q96DE5,Q9HCE1	5
Negative regulation of notch4 signaling	0.3892909421209921	0.8591099469334873	0.3902798599940458	1.0	1.0	40	P49721,Q99436,O75832,P20618,P31749,P28072,P28074,P60900,P28070,P61289	10
Dna replication pre initiation	0.4119690366231804	0.854657221158776	0.3927409396342805	1.0	1.0	53	P49721,Q99436,Q9Y619,O75832,P20618,O75419,P28072,P28074,P60900,P33991,Q14566,P28070,P61289	13
Unfolded protein response upr	0.3778304603654025	0.8390667262206303	0.4014318666649656	1.0	1.0	35	Q92945,Q8N6T3,Q9NWM8,P35611,P43307,O95070,P61421,Q13217,Q9Y5M8,O14773	10
Pyruvate metabolism	0.4547831534726866	0.8363650995558998	0.4029495402729064	1.0	1.0	16	P21796,P35613	2
Retrograde transport at the trans golgi network	0.4954529762913136	0.836347372590929	0.4029595099649534	1.0	1.0	11	Q8N1B4,Q8N2H4,P11717,P20645	4
Golgi associated vesicle biogenesis	0.3838173598785135	0.8271765431687029	0.4081370048265438	1.0	1.0	25	P02786,Q9BXS5,Q9Y5X1,O75976,Q9Y5X3,O60749,P50570,P11717	8
Signal regulatory protein family interactions	0.6595516964348668	0.82655501281463	0.4084893248375016	1.0	1.0	3	P62993	1
Respiratory electron transport	0.3961987673195885	0.8254791076488538	0.4090996391806518	1.0	1.0	46	Q7L592,Q9P0J0,Q9Y6M9,Q86Y39,Q16134,P00403,O14949,P13073,O96000,Q9UDW1,O43676	11
Ub specific processing proteases	0.4272494865968884	0.8240194947990448	0.4099284810781329	1.0	1.0	64	Q15388,P49721,Q86UV5,Q99436,Q9Y277,O75832,P20618,Q96RU2,P21796,P45880,P28072,P28074,P60900,Q96K76,Q9UPU5,P28070,P61289	17
Plasma lipoprotein assembly remodeling and clearance	0.4701403411798153	0.822825771374983	0.4106070790345519	1.0	1.0	14	Q8WTV0,P07237,P61916,O15118	4
Regulation of hmox1 expression and activity	0.3894211957794059	0.7978814476942764	0.4249392904191342	1.0	1.0	44	P49721,Q99436,Q8TCT9,P20618,P28072,P28074,P60900,P09601,P28070,P61289	10
Metabolism of steroids	0.3799710209917272	0.7940429035693325	0.4271704550172193	1.0	1.0	39	P04062,Q9BWD1,Q16850,Q14739,Q14534,Q15392,Q99538,P48449,P37268,Q53GQ0,Q15800,P30536,Q9H4L5,Q9UBM7,P38435	15
Cargo recognition for clathrin mediated endocytosis	0.3720447179607168	0.7835332761360152	0.4333140207923103	1.0	1.0	28	Q14108,P02786,Q9BT78	3
Egr2 and sox10 mediated initiation of schwann cell myelination	0.5114366030484556	0.779318180089798	0.435792307933762	1.0	1.0	6	Q9NR77	1
Tysnd1 cleaves peroxisomal proteins	0.552572338967152	0.7691336089853026	0.4418139981486879	1.0	1.0	5	Q15067	1
Transcriptional regulation by runx3	0.3784159767485972	0.7648837670892163	0.4443407609419623	1.0	1.0	40	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Trans golgi network vesicle budding	0.3656427648305905	0.7647267055491368	0.4444343003501791	1.0	1.0	33	P02786,O14976,Q9BXS5,Q9Y5X1,O75976,Q9Y5X3,O60749,P50570,O43633,P11717,P15586	11
Dna strand elongation	0.3776583594239656	0.752989572135723	0.4514561803423276	1.0	1.0	23	O75419,Q14566,P33991	3
Metabolism of folate and pterines	0.4960286979485739	0.7501645001127837	0.4531556365824751	1.0	1.0	8	Q9H2D1,P41440	2
Regulation of pten stability and activity	0.3766833000104917	0.7498826153250577	0.4533254057049043	1.0	1.0	40	P49721,Q99436,O75832,P20618,P31749,P28072,P28074,P60900,P28070,P61289	10
Constitutive signaling by akt1 e17k in cancer	0.6374278917918725	0.7423577769174118	0.4578705944928725	1.0	1.0	3	P31749	1
Asymmetric localization of pcp proteins	0.3687964050971359	0.7285078361554788	0.4663027735475453	1.0	1.0	37	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Signaling by the b cell receptor bcr	0.3753302979519284	0.7226487832891283	0.4698956890546628	1.0	1.0	41	P49721,Q99436,P62942,P20618,P28072,P28074,P60900,P28070,P61289	9
Scf skp2 mediated degradation of p27 p21	0.3716942150307121	0.7222833320932753	0.4701202984304102	1.0	1.0	39	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Cdc42 gtpase cycle	0.3707168120716536	0.710315862364992	0.4775082853953076	1.0	1.0	24	Q14739,Q9UQB8,Q9H0H5	3
Cyclin a cdk2 associated events at s phase entry	0.3736103395983191	0.7077979538113416	0.4790707372426555	1.0	1.0	41	P49721,Q99436,O75832,P20618,P31749,P28072,P28074,P60900,P28070,P61289	10
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins	0.3975534878370144	0.7026287835665302	0.4822871198732739	1.0	1.0	55	Q7L592,Q9P0J0,Q9Y6M9,Q86Y39,Q16134,P00403,O14949,P20674,P13073,P56385,O96000,O75964,Q9UDW1,O95168,P24539,O43676	16
Cytoprotection by hmox1	0.4073531006689609	0.6991419501595026	0.4844633242157945	1.0	1.0	61	P33527,P49721,Q99436,Q8TCT9,P20618,O75832,O00231,P28072,P28074,P60900,P13073,P09601,P00403,P30519,P28070,P61289	16
Immunoregulatory interactions between a lymphoid and a non lymphoid cell	0.5322332323611052	0.6841464896663528	0.4938826679425347	1.0	1.0	5	Q5KU26	1
Lipophagy	0.6216338714530839	0.6834818837483416	0.4943023938836286	1.0	1.0	3	P54619	1
Platelet calcium homeostasis	0.5746113415001359	0.6828129593484613	0.4947250396881435	1.0	1.0	4	P16615,P23634	2
Reduction of cytosolic ca levels	0.5746113415001359	0.6828129593484613	0.4947250396881435	1.0	1.0	4	P16615,P23634	2
Signaling by notch	0.3926554663674856	0.6756839497604861	0.4992413284776362	1.0	1.0	54	P49721,Q99436,O75832,P20618,P16615,P31749,Q15363,P28072,Q92542,P28074,P60900,Q9UBV2,P28070,P61289	14
Disorders of transmembrane transporters	0.4248435486385284	0.6658694769503701	0.5054945317355537	1.0	1.0	74	O00400,O00231,Q9UBV2,Q9BUN8,Q9BTX1,P61289,Q8NFH4,P49721,P20618,P28072,P28074,O94905,P60900,O75477,Q99436,O75832,P35613,P53985,P28070	19
Rna polymerase iii transcription initiation from type 1 promoter	0.4794063079777518	0.6516047541806468	0.5146561800040703	1.0	1.0	7	Q9Y5Q8,Q9Y5Q9,P62875,Q9UKN8,P19388,O14802	6
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.3741005344963946	0.6509896628639938	0.515053159785305	1.0	1.0	45	P49721,Q99436,O75832,P20618,Q9UJX4,O00231,P28072,P28074,P60900,Q96DE5,P28070,P61289	12
Platelet activation signaling and aggregation	0.3743684421958524	0.6382610051101346	0.5233037914151282	1.0	1.0	46	Q9NUQ9,Q8N2K0,Q08380,P31749,P07602,Q9NZJ7,Q8NBX0,Q9NTK5,O43852,O94919,Q6UXV4	11
Hedgehog on state	0.3634973451428575	0.6359894409510758	0.5247833042911507	1.0	1.0	40	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Binding and uptake of ligands by scavenger receptors	0.4756473040887949	0.6344617203569747	0.525779541026995	1.0	1.0	7	Q5KU26	1
Copi independent golgi to er retrograde traffic	0.3604215453679593	0.6300815376014642	0.528641238324969	1.0	1.0	24	Q9UJW0,O75935,Q10472,P04350,Q13561,Q9BVA1,P68371,Q13885	8
Acyl chain remodelling of pg	0.810370370370377	0.6248861227741744	0.5320458008784974	1.0	1.0	2	Q8NF37	1
Integrin signaling	0.5173926658334148	0.623232998159639	0.5331314201846333	1.0	1.0	5	P31749	1
Platelet aggregation plug formation	0.5173926658334148	0.623232998159639	0.5331314201846333	1.0	1.0	5	P31749	1
Diseases associated with n glycosylation of proteins	0.5583913738468138	0.62147087454995	0.5342898520841746	1.0	1.0	4	Q9BV10	1
Er to golgi anterograde transport	0.4061833148518004	0.6057465134525574	0.5446830919446237	1.0	1.0	67	O14579,P24390,Q96PC5,Q9Y3B3,O95249,Q12907,O15020,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q13885,Q13190,Q9UJW0,Q8IUR0,Q9BVA1,Q8N6T3,Q15363,P49755,O95487	22
The role of gtse1 in g2 m progression after g2 checkpoint	0.3736192318911838	0.6021412190927095	0.5470801390980897	1.0	1.0	48	P49721,Q99436,O75832,P20618,P04350,P07900,O43242,O00231,P28072,P28074,P60900,Q15691,P68371,Q13885,P28070,P53350,P61289	17
Cd28 dependent pi3k akt signaling	0.8022222222222252	0.599382184563029	0.5489180544049488	1.0	1.0	2	P31749	1
Regulation of lipid metabolism by pparalpha	0.4289454837207592	0.5909226167900271	0.5545722712629839	1.0	1.0	14	Q15067,P23786	2
Signaling by gpcr	0.3456862339408106	0.5906815790210659	0.5547337928380092	1.0	1.0	33	Q15418,Q8N2K0,P31749,P07602,Q9NZJ7,P52292,P42892,P30154	8
Ldl clearance	0.4512511501090768	0.5821427476340347	0.5604705333841102	1.0	1.0	10	P61916,O15118	2
Rhobtb3 atpase cycle	0.5433654558932637	0.5658857471897574	0.5714714511012129	1.0	1.0	4	P51151,O60664,O14964	3
Mtorc1 mediated signalling	0.4563159915365661	0.5638686719423001	0.5728435120695483	1.0	1.0	8	P42345,P62942	2
Synthesis of substrates in n glycan biosythesis	0.4334074360693989	0.5466925605401973	0.5845899660978977	1.0	1.0	12	P16278	1
Postmitotic nuclear pore complex npc reformation	0.349922447264996	0.5406524175026801	0.5887471811117446	1.0	1.0	23	Q8NFH4,Q7Z3B4,Q8NFH5,Q92973,P55735,Q8N1F7,Q9BVL2,Q9BTX1	8
Uch proteinases	0.3590854679523019	0.537874826373622	0.5906634688487065	1.0	1.0	44	P49721,Q8NB78,Q99436,P20618,P28072,P28074,P60900,P28070,P61289	9
Signaling by erbb2 ecd mutants	0.5319162591830764	0.524456215143733	0.5999612659147753	1.0	1.0	4	Q16543,P07900	2
Signaling by egfr in cancer	0.5319162591830764	0.524456215143733	0.5999612659147753	1.0	1.0	4	Q16543,P07900	2
Constitutive signaling by egfrviii	0.5319162591830764	0.524456215143733	0.5999612659147753	1.0	1.0	4	Q16543,P07900	2
Constitutive signaling by ligand responsive egfr cancer variants	0.5319162591830764	0.524456215143733	0.5999612659147753	1.0	1.0	4	Q16543,P07900	2
Signaling by erbb2 in cancer	0.5319162591830764	0.524456215143733	0.5999612659147753	1.0	1.0	4	Q16543,P07900	2
Phosphorylation of the apc c	0.4391138613510951	0.5233464655945345	0.6007331712659476	1.0	1.0	10	P30260,Q9UJX3,Q9UJX4,P06493,Q96DE5,P53350	6
Regulation of glucokinase by glucokinase regulatory protein	0.3434174588327489	0.518864148581572	0.6038554801970117	1.0	1.0	26	Q8NFH4,Q7Z3B4,Q8NFH5,Q9BW27,Q92621,Q99567,P35658,P49792,P55735,P12270,Q8N1F7,Q9BVL2,Q9BTX1	13
Sumoylation of sumoylation proteins	0.3434174588327489	0.518864148581572	0.6038554801970117	1.0	1.0	26	Q8NFH4,Q7Z3B4,Q8NFH5,Q9BW27,Q92621,Q99567,P35658,P49792,P55735,P12270,Q8N1F7,Q9BVL2,Q9BTX1	13
Sealing of the nuclear envelope ne by escrt iii	0.4367319648704689	0.5119265084453974	0.6087024449308736	1.0	1.0	10	Q13885,O43633,P04350,P68371	4
Degradation of gli1 by the proteasome	0.3471548589941651	0.5110771061779588	0.6092970660707586	1.0	1.0	39	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein	0.4054912785883744	0.4990144282106138	0.6177692196654703	1.0	1.0	15	P10619,P16278	2
Cellular response to hypoxia	0.3455717930143199	0.4975910938998104	0.6187722823342716	1.0	1.0	39	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Transport to the golgi and subsequent modification	0.3960778566410102	0.4952593731883155	0.620417044787078	1.0	1.0	69	O14579,P24390,Q96PC5,Q9Y3B3,O95249,Q12907,O15020,O75935,P04350,Q9BVK6,O75396,Q13561,P68371,Q13885,Q13190,Q9UJW0,Q8IUR0,Q9BVA1,Q8N6T3,Q15363,P49755,O95487	22
Synthesis of very long chain fatty acyl coas	0.4437192057405362	0.4920749588459749	0.6226663538469719	1.0	1.0	7	Q9P035	1
Muscle contraction	0.3423337078188256	0.4907648306519867	0.6235927871972549	1.0	1.0	24	P16615,P23634,P05023,P08670,P09493,Q9NYL9,P06753	7
Gap junction trafficking and regulation	0.4206711375152348	0.4818226672937173	0.6299319254989071	1.0	1.0	12	Q9BVA1,Q13885,P04350,P68371	4
Notch3 activation and transmission of signal to the nucleus	0.5172303361083601	0.4726451675218761	0.6364663523763887	1.0	1.0	4	Q92542,P67809	2
Fceri mediated nf kb activation	0.3434691403457587	0.4648267027794457	0.642055563655767	1.0	1.0	40	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Formation of atp by chemiosmotic coupling	0.4301250548395381	0.4615796592340493	0.6443827840995051	1.0	1.0	9	P56134,P36542,O75964,P56385,P24539	5
Creb phosphorylation	0.7462962962963031	0.435029911724799	0.66354071597919	1.0	1.0	2	Q15418	1
Cs ds degradation	0.7451851851851925	0.4319792842332937	0.665756469462286	1.0	1.0	2	P06865	1
Chondroitin sulfate dermatan sulfate metabolism	0.7451851851851925	0.4319792842332937	0.665756469462286	1.0	1.0	2	P06865	1
Diseases associated with glycosaminoglycan metabolism	0.7451851851851925	0.4319792842332937	0.665756469462286	1.0	1.0	2	P06865	1
Release of apoptotic factors from the mitochondria	0.5487176366756672	0.4308767935857838	0.6665579579864984	1.0	1.0	3	O60443	1
Budding and maturation of hiv virion	0.421826419779557	0.409924070949578	0.6818616471782595	1.0	1.0	8	Q96PU5,O43633	2
Ptk6 regulates proteins involved in rna processing	0.73703703703704	0.4098940244931421	0.6818836889785844	1.0	1.0	2	P23246	1
Metabolism of steroid hormones	0.4981346656186344	0.4078266269535438	0.6834009635876455	1.0	1.0	4	P30536	1
Gab1 signalosome	0.5400649296954491	0.4036336003519624	0.6864821736132063	1.0	1.0	3	P62993	1
Antigen processing cross presentation	0.3479309708204622	0.4006811290826635	0.6886549061478866	1.0	1.0	47	P49721,P61289,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,Q9UIQ6	10
Enos activation	0.539106532935415	0.4006592207460238	0.6886710381915828	1.0	1.0	3	P31749	1
Downregulation of erbb2 signaling	0.4547558114767042	0.3815116437500158	0.7028236329154205	1.0	1.0	5	P31749,Q16543	2
Apc c cdc20 mediated degradation of cyclin b	0.4121453485962364	0.3811088487953876	0.7031224816451218	1.0	1.0	9	P30260,Q9UJX3,Q9UJX4,P06493,Q96DE5	5
Visual phototransduction	0.4899050385690461	0.3808859335021386	0.7032878906109317	1.0	1.0	4	Q6NUM9	1
Tgf beta receptor signaling activates smads	0.408564279189218	0.3805101683711855	0.7035667499338765	1.0	1.0	10	Q96PU5	1
Signaling by braf and raf1 fusions	0.3288588642439629	0.379649310805841	0.7042057518021538	1.0	1.0	22	Q9NRY5	1
Pi3k akt signaling in cancer	0.4156976112942943	0.3734706714624402	0.7087981696290371	1.0	1.0	7	P31749,P42345,P62993	3
Aberrant regulation of mitotic exit in cancer due to rb1 defects	0.4132477190229744	0.3732601396412648	0.7089548400851833	1.0	1.0	8	P30260,Q96DE5,Q9UJX3,Q9UJX4	4
Rna polymerase iii transcription	0.4131403118039944	0.3728059502022959	0.7092928739868072	1.0	1.0	8	Q12789,Q9Y5Q8,Q9Y5Q9,P62875,Q9UKN8,P19388,O14802	7
Sumoylation of rna binding proteins	0.3183716537887328	0.3704384825186391	0.7110558050598019	1.0	1.0	30	Q8NFH4,Q7Z3B4,P61978,Q8NFH5,Q92621,Q99567,P35658,P55735,P07910,Q8N1F7,Q9BVL2,Q9BTX1	12
Interleukin 1 signaling	0.3345812330768665	0.3612788470848016	0.7178910049598466	1.0	1.0	42	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Rna polymerase iii transcription initiation from type 3 promoter	0.5235272323082613	0.3535807882745647	0.7236530741860925	1.0	1.0	3	P19388,O14802	2
Rna polymerase iii chain elongation	0.5235272323082613	0.3535807882745647	0.7236530741860925	1.0	1.0	3	P19388,O14802	2
Dna damage reversal	0.4807264640474564	0.3516113314094081	0.7251297659880644	1.0	1.0	4	Q6P6C2,Q8N3C0,Q9H1I8	3
Rnd1 gtpase cycle	0.3937277195732708	0.3494368658299309	0.7267613606005219	1.0	1.0	12	P51648,P02786,P38159,O75976	4
Rhod gtpase cycle	0.3219236383855198	0.3438022386768138	0.7309950165289383	1.0	1.0	25	Q14739,O15173,Q9H0H5	3
Sumoylation of ubiquitinylation proteins	0.3192627610160651	0.3400375592409527	0.733828243208573	1.0	1.0	27	Q8NFH4,Q7Z3B4,Q8NFH5,Q9BW27,Q92621,Q99567,P35658,P49792,P55735,P12270,Q8N1F7,Q9BVL2,Q9BTX1	13
Gastrin creb signalling pathway via pkc and mapk	0.4425179444721022	0.3382261972805656	0.7351927353987386	1.0	1.0	5	Q15418,P62993	2
Deubiquitination	0.3936173121756586	0.3347169747048882	0.7378385953948765	1.0	1.0	80	Q86UV5,P21796,P45880,P61289,Q15388,P49721,P20618,P28072,P28074,P60900,Q8NB78,Q99436,O75832,Q96K76,Q9UPU5,Q9Y277,O95630,Q96RU2,P28070	19
Nuclear import of rev protein	0.3132485029940183	0.3282780589272593	0.7427014322191043	1.0	1.0	30	P37198,Q9UKX7,P78406,P49792,O75694,Q14974,Q9BTX1,Q8NFH4,Q7Z3B4,Q8TEM1,Q12769,P35658,Q8N1F7,P55735,P12270,Q8NFH5,Q9BW27,Q92621,P52948,P57740,P06748,Q8WUM0,Q96EE3,Q5SRE5,Q99567,P18754,P62826,Q9BVL2,Q9NRG9	29
Tcr signaling	0.3322868437221282	0.3281941422321187	0.7427648766082351	1.0	1.0	43	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Depolymerisation of the nuclear lamina	0.4007112194466352	0.3211225938087634	0.7481174889211784	1.0	1.0	8	P50402,P42167,P06493,Q9Y2U8	4
Bicarbonate transporters	0.696666666666671	0.308474205841748	0.7577215246580455	1.0	1.0	2	P04920	1
Export of viral ribonucleoproteins from nucleus	0.3130142109199877	0.3015203981555321	0.7630176978522307	1.0	1.0	28	P37198,Q9UKX7,P78406,P49792,O75694,Q9BTX1,Q8NFH4,Q7Z3B4,Q8TEM1,Q12769,P35658,Q8N1F7,P55735,P12270,O14980,Q8NFH5,Q9BW27,Q92621,P52948,P57740,Q8WUM0,Q96EE3,Q5SRE5,Q99567,P62826,Q9BVL2,Q9NRG9	27
Interleukin 1 family signaling	0.3299738541589391	0.2953561758135183	0.7677218073477348	1.0	1.0	44	P49721,Q99436,O75832,P20618,P28072,P28074,P60900,P28070,P61289	9
Nade modulates death signalling	0.6903703703703694	0.2939472472047059	0.7687982139999683	1.0	1.0	2	P62258	1
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling	0.3926344291136606	0.2885366728662407	0.7729359626724777	1.0	1.0	8	Q15418	1
Antigen presentation folding assembly and peptide loading of class i mhc	0.3764348190262365	0.2883037215980212	0.7731142586247117	1.0	1.0	13	P10321,Q9NZ08	2
Cytosolic iron sulfur cluster assembly	0.4276836628511209	0.2879854748451033	0.7733578572818374	1.0	1.0	5	O75027	1
Activation of nmda receptors and postsynaptic events	0.3148335002657749	0.2826078095309333	0.7774774931459338	1.0	1.0	23	Q15418,P07196,P04350,P52292,P68371,Q13885,P54619	7
Formation of tubulin folding intermediates by cct tric	0.3732032978906245	0.2729751444435522	0.7848723220791958	1.0	1.0	13	P50991,P04350,Q9BVA1,P68371,Q13885	5
Collagen biosynthesis and modifying enzymes	0.3839621523608718	0.2726979706081181	0.7850853948224277	1.0	1.0	10	O15460,P07237,P13674,Q32P28	4
Mitochondrial biogenesis	0.3080454480062097	0.2715139496696833	0.785995772247428	1.0	1.0	33	Q13505,Q5XKP0,Q9NX63,Q9BUR5,O75964,P56385,P24539,O75431,Q6UXV4,P54619	10
Copii mediated vesicle transport	0.3093031401605725	0.2636980389237414	0.7920126067775519	1.0	1.0	27	Q12907,Q13190,Q15363,O75396,Q8IUR0,O95487	6
Signaling by flt3 fusion proteins	0.4498514087221418	0.2597933465512891	0.795023183474552	1.0	1.0	4	Q01082,P62993	2
Lysosome vesicle biogenesis	0.3686113437254424	0.2514680597939364	0.801452253521344	1.0	1.0	13	Q9BXS5,P09497,P50570,O43633,P15586,P20645	6
Methionine salvage pathway	0.4858735706362125	0.2507367847721358	0.8020176187976842	1.0	1.0	3	Q13126	1
Fcgamma receptor fcgr dependent phagocytosis	0.3101910136989415	0.2499855083047984	0.8025985556074389	1.0	1.0	23	Q96F07,Q9UQB8,Q8IV08	3
Signaling by type 1 insulin like growth factor 1 receptor igf1r	0.4458858413639761	0.2488110850676786	0.8035069160675317	1.0	1.0	4	O14654,Q06124,P62993	3
Signalling to ras	0.4451445515196523	0.2467799394954734	0.8050785363798454	1.0	1.0	4	P11233,P11234,P62993	3
Potential therapeutics for sars	0.3062477301533527	0.2426644482055318	0.8082653505494095	1.0	1.0	34	Q99720,P21964,P07437,P62942,P05023	5
Recycling of eif2 gdp	0.3821337867535962	0.2425922978095806	0.8083212484686484	1.0	1.0	7	Q9NR50	1
G alpha q signalling events	0.3786777279723149	0.2410828927038607	0.8094908714400557	1.0	1.0	9	Q15418,Q8N2K0,P62993	3
Mitotic g1 phase and g1 s transition	0.3551598380419838	0.2318203970781618	0.8166775139831572	1.0	1.0	64	P49721,Q99436,Q9Y619,O75832,P20618,P31749,O75419,O00231,P28072,P28074,P60900,P33991,Q14566,P28070,P61289	15
Nicotinamide salvaging	0.4749837735399391	0.2241791638690625	0.822617895715315	1.0	1.0	3	P43490	1
Regulation of tp53 activity through methylation	0.6551851851851858	0.219750539556934	0.8260654417012887	1.0	1.0	2	O14744	1
G2 m checkpoints	0.3678701473544732	0.2192712060421821	0.8264387903711259	1.0	1.0	73	P49721,Q99436,O75832,P20618,Q9UQ84,O75419,P28072,P28074,P60900,P33991,Q14566,O96028,P28070,P61289	14
Bile acid and bile salt metabolism	0.4037787558046412	0.2128398832921511	0.8314518540336955	1.0	1.0	5	Q9H4L5	1
Synthesis of bile acids and bile salts	0.4037787558046412	0.2128398832921511	0.8314518540336955	1.0	1.0	5	Q9H4L5	1
Nephrin family interactions	0.3736549165120564	0.2119371184043122	0.8321560920067577	1.0	1.0	7	Q13813,P46940,O14936,Q9Y5K6,Q01082,O43707	6
Mhc class ii antigen presentation	0.3354862378377835	0.2057021816836012	0.8370235542685398	1.0	1.0	54	Q14203,O15020,Q9UJW0,O75935,P10619,P52732,Q9BXS5,O95487,P04350,Q9H0H5,Q99538,Q13561,P50570,Q9BVA1,P68371,Q13885,Q9UQ16	17
Degradation of the extracellular matrix	0.371795602610023	0.2053611838552012	0.8372899447253763	1.0	1.0	7	Q92542	1
Signaling by hedgehog	0.3369055976360408	0.2039185238677073	0.8384171692657967	1.0	1.0	55	P49721,Q99436,O75832,P20618,O43242,O00231,P28072,P28074,P60900,P07237,Q9UBV2,Q13885,P68371,P28070,P61289	15
Hedgehog off state	0.3285887768336817	0.2036592615650479	0.8386197794765373	1.0	1.0	50	P49721,Q99436,O75832,P20618,O43242,P28072,O00231,P28074,P60900,P68371,Q13885,P28070,P61289	13
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components	0.3685164793899214	0.2016761271705081	0.8401699268617315	1.0	1.0	9	P30260,Q96DE5,Q9UJX4	3
Apc cdc20 mediated degradation of nek2a	0.3685164793899214	0.2016761271705081	0.8401699268617315	1.0	1.0	9	P30260,Q96DE5,Q9UJX4	3
Flt3 signaling in disease	0.3969508848896229	0.1928268510246845	0.8470945740322919	1.0	1.0	5	P62993,Q01082	2
Met activates ras signaling	0.4602097522472178	0.1906123545026876	0.8488293101725866	1.0	1.0	3	P62993	1
Rho gtpases activate iqgaps	0.3598585971430049	0.1841844907025071	0.8538687259641204	1.0	1.0	11	Q13885,P04350,P68371	3
Cd28 co stimulation	0.3654282922207965	0.1830009894607869	0.8547972422512764	1.0	1.0	6	P31749,P42345	2
Regulation of runx2 expression and activity	0.312026347083975	0.1793321554109627	0.8576768997281268	1.0	1.0	42	P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289	8
Nuclear envelope ne reassembly	0.323208913100421	0.1747869880506957	0.8612470129763861	1.0	1.0	49	P30153,P42167,Q9BTX1,Q8NFH4,Q7Z3B4,Q86Y07,P04350,P06493,Q8N1F7,P68371,Q13885,Q9Y2U8,Q8NFH5,P50402,Q9BVA1,Q86XL3,Q14739,Q92973,O43633,Q9BVL2	20
Tp53 regulates metabolic genes	0.2938642257146237	0.1735153539365471	0.8622463602337878	1.0	1.0	30	O94925,P31749,Q9NQ88,P00403,P20674,P13073,O75880,P54619	8
Aggrephagy	0.3470176648843439	0.1711576464781822	0.8640998092174916	1.0	1.0	14	P04350,P07900,P08670,P68371,Q13885	5
Nicotinate metabolism	0.4148908983500759	0.1700468828424739	0.8649732663466252	1.0	1.0	4	P43490	1
Regulation of plk1 activity at g2 m transition	0.2927701001269132	0.1650528497451446	0.8689023843644668	1.0	1.0	30	P07437,O75935,O43805,P04350,P07900,Q13561,Q15691,O94927,P68371	9
Rna polymerase iii transcription termination	0.4125277983691644	0.164581504992844	0.8692733895619185	1.0	1.0	4	P62875,P19388,O14802	3
Rhobtb gtpase cycle	0.294955003492364	0.163997406978041	0.869733185106861	1.0	1.0	28	Q16543,P62995,P07900,P08670,P07910,Q9BT78,Q99832,Q9NYL9,P38159	9
Transcriptional activity of smad2 smad3 smad4 heterotrimer	0.3576017638426776	0.1612409308343592	0.8719036447159112	1.0	1.0	9	P50750,Q96PU5	2
Irs mediated signalling	0.4457206372730616	0.1605395332764479	0.872456082406583	1.0	1.0	3	Q06124,P62993	2
Apoptotic factor mediated response	0.3584036664027911	0.1603734331860368	0.8725869159776554	1.0	1.0	6	O60443	1
Synthesis of pips at the er membrane	0.6214814814814837	0.1603448001985835	0.8726094699359526	1.0	1.0	2	Q9NTJ5	1
P38mapk events	0.44497962208225	0.1590786656698428	0.8736068964972876	1.0	1.0	3	P11233,P11234	2
Diseases of mitotic cell cycle	0.3535410252937895	0.1515635158409965	0.8795312110356119	1.0	1.0	10	P30260,Q96DE5,Q9UJX4	3
Tnfr2 non canonical nf kb pathway	0.3047951349694354	0.1494907716568046	0.8811663906988199	1.0	1.0	40	P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289	8
Dectin 1 mediated noncanonical nf kb signaling	0.3047951349694353	0.149490771656804	0.8811663906988203	1.0	1.0	40	P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289	8
Protein folding	0.2945344830535127	0.1494731516374927	0.8811802932440775	1.0	1.0	34	P50991,P04062,Q9Y2T2,P04350,Q9BVA1,P68371,Q13885,Q99471,O15212	9
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.2899045667233744	0.1430518642188221	0.8862492206365928	1.0	1.0	30	Q9UJW0,O75935,P04350,P07900,Q13561,Q9BVA1,P68371,Q13885	8
Ctla4 inhibitory signaling	0.3765938179430496	0.1373419168929278	0.8907605394484797	1.0	1.0	5	P31749	1
Signaling by hippo	0.3505192878338281	0.1359689424359629	0.8918458332551022	1.0	1.0	6	P31946,Q13043,Q4VCS5,P62258,Q07157	5
Neurotransmitter release cycle	0.3500501184228537	0.1345507861909557	0.8929670545785804	1.0	1.0	6	Q96QD8	1
Tp53 regulates transcription of death receptors and ligands	0.6007407407407439	0.1296068282182423	0.8968775006821503	1.0	1.0	2	P04637	1
Recycling pathway of l1	0.2921724842365402	0.1290679202943834	0.8973039055486862	1.0	1.0	22	Q15418,P04350,P50570,Q9BVA1,P68371,Q13885,Q9UQ16	7
P75 ntr receptor mediated signalling	0.3405251148349897	0.1279348059902627	0.8982005661654173	1.0	1.0	13	Q9NQC3	1
Regulated necrosis	0.3172763551449177	0.1201234998227095	0.9043853170121384	1.0	1.0	18	Q16543,P41440,P07900,O60443,O43633,Q8WUM4	6
Synthesis of dna	0.3514332514103226	0.1190144623444251	0.9052638979257486	1.0	1.0	71	P49721,Q99436,Q9Y619,O75832,P20618,P41440,Q9UJX4,O75419,O00231,P28072,P28074,P60900,Q96DE5,P33991,Q14566,P28070,P61289	17
Sting mediated induction of host immune responses	0.3445845697329386	0.1183188640132093	0.9058150110649748	1.0	1.0	6	P12956,P19474,P78527,P49959,Q9UJV9	5
Pkmts methylate histone lysines	0.3253706042251609	0.1105805543713189	0.9119489682654502	1.0	1.0	16	Q03164	1
Methylation	0.3416964007913537	0.1099592906993874	0.912441660391336	1.0	1.0	6	P21964	1
Ripk1 mediated regulated necrosis	0.3405972860778701	0.1098899532924602	0.9124966503983988	1.0	1.0	11	Q16543,P41440,O75955,P07900,O00560,Q8WUM4	6
Degradation of beta catenin by the destruction complex	0.3075625813536511	0.1063492928979454	0.9153052232337102	1.0	1.0	45	P49721,Q99436,O75832,P20618,P28072,O00231,P28074,P60900,P30154,P28070,P61289	11
Pcp ce pathway	0.3105982795372534	0.1040982645307242	0.917091368080974	1.0	1.0	47	P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289	8
Death receptor signalling	0.3140933968449652	0.1037976872342182	0.9173299018763534	1.0	1.0	18	Q9NQC3,Q8TCT8	2
Sulfur amino acid metabolism	0.3403804502961686	0.101835270590796	0.9188874292852078	1.0	1.0	9	Q9UBX3,Q13126	2
Hur elavl1 binds and stabilizes mrna	0.3611420096403448	0.0996586665083292	0.920615316463685	1.0	1.0	5	Q15717,P39687,P35658,Q01105	4
Senescence associated secretory phenotype sasp	0.3268767629672173	0.0988325622056715	0.9212712141515556	1.0	1.0	15	P30260,Q15418,Q9UJX3,Q9UJX4,P51812,Q96DE5	6
Cellular response to chemical stress	0.3468779321495527	0.0970951062350578	0.9226508671592542	1.0	1.0	70	P33527,P49721,Q99436,Q8TCT9,P20618,O75832,O00231,P28072,P28074,P60900,P13073,P09601,P00403,P07237,P30519,P28070,P61289	17
Rsk activation	0.3763901094248166	0.0911220507893765	0.9273956115342628	1.0	1.0	4	Q15418	1
Nuclear receptor transcription pathway	0.5670370370370417	0.0889202985002882	0.9291452515814064	1.0	1.0	2	Q9UHY1	1
Dissolution of fibrin clot	0.3994071878473516	0.0838058149961509	0.933210824589158	1.0	1.0	3	P60903,P35237	2
Nuclear pore complex npc disassembly	0.2823299546959419	0.0731223340862934	0.9417087692	1.0	1.0	28	Q8NFH4,Q7Z3B4,Q8NFH5,Q92621,Q99567,P35658,P55735,P06493,Q8N1F7,Q9BVL2,Q9BTX1	11
Organelle biogenesis and maintenance	0.3666095334239652	0.0726034543898101	0.942121677771992	1.0	1.0	85	Q14203,P56134,P50991,O43805,P07900,Q9BUR5,O94927,O43924,A6NIH7,Q6UXV4,P07437,O75935,Q13505,P04350,Q13561,P68371,Q13885,P53350,P54619,Q10713,Q9NX63,Q9BVA1,P56385,Q16891,Q92973,Q7Z4L5,Q15691,Q5XKP0,O75964,A0AVF1,P24539,O75431	32
Ncam signaling for neurite out growth	0.3219075264286125	0.0568987565746951	0.9546258448197767	1.0	1.0	6	O15020,P62993	2
Pd 1 signaling	0.5303703703703683	0.0567493262118274	0.9547448806622107	1.0	1.0	2	P41240	1
Biological oxidations	0.2891129404921569	0.0566245948991841	0.9548442420778758	1.0	1.0	38	P16435,O43169,Q9NUJ1,Q9H2H9,P21964,Q16850,Q8TB61	7
Auf1 hnrnp d0 binds and destabilizes mrna	0.2938978259604513	0.0546601803978155	0.9564091933487004	1.0	1.0	41	P49721,Q99436,P20618,P28072,P28074,P60900,P28070,P61289	8
Apc c mediated degradation of cell cycle proteins	0.3104728510666063	0.0544663922103489	0.956563583957994	1.0	1.0	51	P49721,Q99436,O75832,P20618,Q9UJX4,O00231,P28072,P28074,P60900,Q96DE5,P28070,P61289	12
Rho gtpases activate wasps and waves	0.3184914209228799	0.0510078482858775	0.959319266663332	1.0	1.0	14	Q96F07,Q9UQB8	2
Formation of tc ner pre incision complex	0.2793757887909888	0.0468157009118879	0.962660115236076	1.0	1.0	26	Q16531	1
Synthesis of pips at the golgi membrane	0.3181287361265418	0.0370569958746017	0.970439560779078	1.0	1.0	8	Q10713,Q9BTU6	2
Signaling by leptin	0.4951851851851916	0.0360284296375621	0.9712596900924166	1.0	1.0	2	Q06124	1
Interleukin 37 signaling	0.4951851851851916	0.0360284296375621	0.9712596900924166	1.0	1.0	2	Q06124	1
Activation of smo	0.4792592592592551	0.02934848458854	0.976586658428176	1.0	1.0	2	P48729	1
Smooth muscle contraction	0.3162393162393119	0.027054630073676	0.9784161614573552	1.0	1.0	11	P18206,P04083,P67936,Q13177,Q9Y490,P09493,Q05682,P07355,P06753,P60660	10
Inhibition of replication initiation of damaged dna by rb1 e2f1	0.329132690882132	0.0240592791646197	0.9808053244312174	1.0	1.0	4	P30154,P30153,P49643	3
Dna replication initiation	0.3290107447202636	0.0196113669081414	0.984353396096388	1.0	1.0	3	Q07864,P49643	2
Cd163 mediating an anti inflammatory response	0.4448148148148221	0.0193826726724864	0.9845358330172505	1.0	1.0	2	P35579	1
Signaling by erbb2	0.3110378394051266	0.0186990805594997	0.9850811617346906	1.0	1.0	8	P31749,Q16543,P07900	3
Miro gtpase cycle	0.3221459682737674	0.0168041136959448	0.986592888106436	1.0	1.0	4	Q8IWA4	1
Ngf stimulated transcription	0.3544444444444407	0.0103811849040366	0.9917171616146984	1.0	1.0	2	P50570	1
Ns1 mediated effects on host pathways	0.2742234142413744	0.0100456849415129	0.991984837892101	1.0	1.0	33	Q8NFH4,Q7Z3B4,Q8NFH5,Q86U42,Q92621,P35658,P52292,P55735,Q8N1F7,Q9BVL2,Q9BTX1	11
Reactions specific to the complex n glycan synthesis pathway	0.338888888888888	0.0100163225222138	0.9920082645344904	1.0	1.0	2	P04066	1
N glycan antennae elongation in the medial trans golgi	0.338888888888888	0.0100163225222138	0.9920082645344904	1.0	1.0	2	P04066	1
Pyroptosis	0.3041127732888067	0.008231234047538	0.9934324995987416	1.0	1.0	7	O60443	1
Initiation of nuclear envelope ne reformation	0.2975180841340489	0.0049194353030556	0.9960748743557216	1.0	1.0	17	Q86XL3,P30153,Q86Y07,P42167,Q14739,P50402,P06493,Q9Y2U8	8
Vegfr2 mediated vascular permeability	0.3073171690868391	0.0047979128641021	0.9961718340890372	1.0	1.0	9	P31749,P07900	2
Aryl hydrocarbon receptor signalling	0.290848462393474	0.0047555206920634	0.9962056577627232	1.0	1.0	3	P08238,O00170	2
Dap12 interactions	0.3071946255555544	0.0033712014301551	0.9973101755224992	1.0	1.0	4	P10321	1
Suppression of apoptosis	0.2782512041496803	0.0018722305239396	0.9985061770433878	1.0	1.0	3	P28482,P23246	2
Cytochrome c mediated apoptotic response	0.2782512041496792	0.0018722305239393	0.998506177043388	1.0	1.0	3	P28482,Q9NR28	2
Formation of apoptosome	0.2782512041496792	0.0018722305239393	0.998506177043388	1.0	1.0	3	P28482,Q9NR28	2