diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cf1ac64dd837eb5e626b47a909e471e60e7c1bd5 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:698b34a41690f06699e7d70e5317a2aefaff5cbb60f3a7057e5556dc142ed6d3 +size 74177 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5dae34e35dda32a96b3004a6b088e5ecf7b025f5 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 55, + "title": "Average number of proteins per term", + "value": 2.3454545454545452 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9c7ad6db525f8f9a2006b0eeb5f296fe6727780d --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..714b64dbe6a0805f5dc34c05ade96ccd0ca372bf --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein-tyrosine phosphatase, active site [IPR016130] 0.7475423030037595 1.9059118602760496 0.0566616420166723 0.9595692150252766 0.0916585385563817 5 Q06124,Q9Y217 2 +Tyrosine-protein kinase, active site [IPR008266] 0.4866500533997882 0.7114169791273878 0.4768258804312135 0.9999999999999996 0.494819309881448 3 P08069,Q13308 2 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..eb067ea80f5e26354d2522bb1ca562ecb44f4791 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K4", "MAPK1", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TXNRD2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["IGF1R", "MTMR6", "PTK7", "PTPN11"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..465c03bba181ece1b3cfc758ab37913f62157507 --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein kinase, ATP binding site [IPR017441]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ca42eea503e4989224afc07f57f72407663179d5 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15ebee6df36a5d6fd4e4469560dfc3848365ae51812530d3f7092981b4bdc17e +size 152659 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..257bbf1a01978eeca42757872684132878f9f250 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a750efc3cece497fd82e523e0f4b65a7137322718c3347ad21e83515c387c26 +size 67402 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..9aed39511efe3787171c1f245f51ba9acae7fead --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 3.806451612903226 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..cb9a61f202066b730a011157d6d42e2bbc7b1dc5 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..65123e40c939cdc10128f3141cf34e6f6bae3e08 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Beta tubulin, autoregulation binding site [IPR013838] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.1167651593718568 0.0413052768843338 4 P07437,Q9BVA1,P68371 3 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.6896797153024917 1.661954654851331 0.096521866778835 0.9570021221938438 0.1662321038968825 2 O15270 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.5384290217989485 0.8920402164261976 0.3723713768252183 0.9999994644685432 0.4275375067252507 32 P80303,Q14257,O43852,Q9BPX6 4 +Protein kinase, ATP binding site [IPR017441] 0.4249879613142504 0.2946602512176263 0.768253430576133 1.0 0.7938618782620042 31 Q13555,Q02750,P31751,Q15418,Q7L7X3,P51812 6 +Peptidase M16, zinc-binding site [IPR001431] 0.2959674514509485 0.0313458679346518 0.9749937110412216 1.0 0.9749937110412216 5 O43847,P22695 2 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2277c036d3eab0daf3f0d134118766385ba45965 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "LETM1", "MACF1", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TAOK1", "TBK1", "TKT", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["AKT2", "CALU", "CAMK2G", "MAP2K1", "MICU1", "NRDC", "NUCB2", "RCN2", "RPS6KA1", "RPS6KA3", "SPTLC2", "TAOK1", "TUBB", "TUBB2B", "TUBB4B", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..51dfa88214da95d148dbffb95702a7d49fe6a369 --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "14-3-3 protein, conserved site [IPR023409]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9812e6e5121ba0b5ce3e83a558e8a4e982265bb3 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bf97fbf9fd94034fe353d0a936e9576f661c458b775f15656d09ec15178e767 +size 135681 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..6944ce98ae42925c8fea7207f518ea7970a2771d --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f11fd59bdfb5a44cbb653d8fe026df514a888eeabb1fb01bec6c423c75ebb3a8 +size 104916 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7b57f4796965e95acd5e8b9397177f99a1d37f18 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 3 8 2.103424254989008 0.0354287000581681 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0073045224575045 0.0461123069087121 0.0038356556834428 0.0014512760162947 0.0009118158302113 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6b08053b963166071cb83a340acfb114c6c3b277 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 259, + "title": "Average number of proteins per term", + "value": 2.6563706563706564 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..bd156ebd037fbd275f83ecd21db3a2868fd4f9f2 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..74a50c9dc005e1afae62e69a48a1e3ddb72e3692 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,23 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tubulin, conserved site [IPR017975] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.645615039415073 0.0680995721282667 4 P07437,Q9BVA1,P68371 3 +Haem oxygenase conserved site [IPR018207] 0.961209964412814 2.828944238364937 0.00467018352802 0.7025207585554116 0.0680995721282667 2 P30519 1 +Guanylate kinase, conserved site [IPR020590] 0.8283475783475766 2.2683797711751628 0.0233060696342155 0.99777439235867 0.0804836271368243 4 O14936,Q14168,Q9NZW5 3 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.7930565378443377 2.1141219392840016 0.0345048537988892 0.999887727199614 0.1015540583399126 4 P48735 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.7930087995545346 2.103424254989008 0.0354287000581681 0.9999123820791468 0.10231491205195 8 P49721,P28074,P28072 3 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.7757208971164249 2.0426132702052024 0.0410907364163739 0.9999809288812848 0.1052150463798231 3 P01889,P04439 2 +Syntaxin/epimorphin, conserved site [IPR006012] 0.7554760599960736 1.9417435569749664 0.0521681528835342 0.9999990593980084 0.1195712530693396 5 Q9P2W9 1 +DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.6889679715302486 1.658700992761141 0.0971760592580728 0.999999999996829 0.1770314262686313 2 O15160 1 +Ubiquitin specific protease, conserved site [IPR018200] 0.6601291415901305 1.4753351469157778 0.1401224616394007 1.0 0.2265066994725471 14 Q96K76,Q8TEY7,P40818 3 +Thioredoxin, conserved site [IPR017937] 0.6536814343773623 1.4505751280931871 0.1468982052115937 1.0 0.2305856675745622 10 Q9H3N1,Q8IXB1,Q9H1E5,O43396 4 +Annexin repeat, conserved site [IPR018252] 0.6161361271243933 1.2831073210839974 0.1994544792212313 1.0 0.2822880334333275 7 P12429,P04083,P50995 3 +Actin, conserved site [IPR004001] 0.5975088967971487 1.2349211167846477 0.2168598635560954 1.0 0.299449663000262 2 O96019 1 +Ribosomal RNA adenine methylase transferase, conserved site [IPR020596] 0.5918149466192159 1.2083001048839015 0.2269318481464353 1.0 0.3077243385860039 2 Q9UNQ2 1 +DnaJ domain, conserved site [IPR018253] 0.5238222983995261 0.8303115792944545 0.406362642941386 1.0 0.4714162691952762 9 Q9NVH1,Q99543,Q9UBS4,Q96KC8 4 +Sterol reductase, conserved site [IPR018083] 0.5099644128113839 0.8279278388180145 0.4077113679526714 1.0 0.4714162691952762 2 Q14739 1 +14-3-3 protein, conserved site [IPR023409] 0.4878831076265084 0.6864183575243016 0.4924493315457794 1.0 0.5474488994473786 6 Q04917,P61981,P31946,P63104,P62258 5 +RNA polymerase, beta subunit, conserved site [IPR007121] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5474488994473786 3 P30876,Q9NW08 2 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.4737355887024673 0.6144095193546951 0.5389447468634239 1.0 0.5939859125005396 7 P51648 1 +Oxysterol-binding protein, conserved site [IPR018494] 0.4435747931316665 0.5020941899767134 0.6156012669170752 1.0 0.6643363672146769 5 Q9BZF3 1 +Alcohol dehydrogenase, zinc-type, conserved site [IPR002328] 0.4049822064056922 0.3787058514236199 0.7049063076654625 1.0 0.7421574540055073 2 Q00796 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.8722717805569966 6 Q14566 1 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.275997150997149 0.0060245593198355 0.9951931262109128 1.0 1.0 4 P42345,O00443,P42356 3 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..dd9560c0f472d717bff02ff16f5e52b17c796121 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX35", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MFSD14B", "MID1", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NEFM", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ACTL6A", "ALDH3A2", "ANXA1", "ANXA11", "ANXA3", "CASK", "DIMT1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "HLA-A", "HLA-B", "HMOX2", "IDH2", "LBR", "MCM6", "MPP2", "MPP6", "MTOR", "OSBPL6", "PI4KA", "PIK3C2A", "POLR1C", "POLR2B", "POLR3B", "PSMB2", "PSMB5", "PSMB6", "SORD", "STX18", "TMX1", "TMX4", "TUBB", "TUBB2B", "TUBB4B", "TXNL1", "USP33", "USP47", "USP8", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..3d600e125326bf1e19497a955f36c799201185f6 --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "GOLD domain [IPR009038]", "1": "RNA recognition motif domain, eukaryote [IPR003954]", "2": "DnaJ domain [IPR001623]", "3": "EF-hand domain [IPR002048]", "4": "14-3-3 domain [IPR023410]", "5": "Thioredoxin domain [IPR013766]", "6": "K Homology domain, type 1 [IPR004088]", "7": "K Homology domain [IPR004087]", "8": "RNA recognition motif domain [IPR000504]", "9": "Band 7 domain [IPR001107]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..582ba1b4a685204feabc4839712f604e2a280094 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db718f5a6fe26bf860951580f8e35cc9296dea9ffbd757781a311da8797155cf +size 127408 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8122a9452ac1896cfa18f5ee064a6fd1c56c0af4 --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d64d5ca7ccb4533b5d6b3db12e375df690e3f06d5ab57252f202c8036e57e4aa +size 142919 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e3a3f20ecf59f3821b008fb5f2062d929e2aa917 --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3887eeb2f2a428148daa020963dd2fd016cb1dfa095b224fb823e4247e573f7 +size 133316 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f719c17ec5b88549e4833d3ae1d291edb3a0beec --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:98e8670738e11b23aa2d5e2dc8906869c3f133c177e43655e96d7da60d84b949 +size 134102 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..436e30583e7617e6aca8d90bf4b2484ae19edb83 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:efce6de7ca03f38824a679903816cc34ccc611e5b23e45096ca6d8c913b1dd76 +size 128059 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..db84d48bb1cac9847bb0e8cc738e222f63fd336f --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c86f304e261f54527590e8d3cb24c4ec823eddd6fde6fe012a99a25ba43257f1 +size 142359 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..733fdf1190ed5d0342806b7431d7a47df0070bba --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5449a7ea93f73c8a66942fd40e221d87e497ae8c7e74a42ce2499bedca571f67 +size 147641 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e4973a8895c536629d8cdd616e0853616833626d --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:49d4da415789fe0797935ca37822ee5b1a90c605a1ce4c3d46c352493cac6562 +size 141298 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..c3f48fa205460aeb73844856cf58297d3eaa8a4e --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c423b21d62c83ccd6aabb1c30eb4df6e12cf1b672d87f512a79723dfcd4aa20 +size 148988 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..3b537e58d026f3ee5cfc280ce51ce4453d24a1ff --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a1bf95b83918966f88096dea3846a9fe93ae0581f004f5cc245db1d51866f28 +size 122525 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e87c758ad2542d2bf25ff5f37ed5153063ee6dff --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d903b6fbd05eeea1f672c8c335dcf109bf28a15575a8446e8c69a3965e73fc65 +size 446927 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f0bc80eb2279f55c027ad318cf9d42c1d184c806 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 5 2.6094504570171084 0.0090687776771443 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 1.3401087212461636e-05 0.0550816697898294 0.0001725606130307 0.0001383364889708 0.0001575214550341 +Aminopeptidase N-like , N-terminal domain [IPR045357] 4 6 2.0719030355602435 0.0382744848323288 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.004624601375411 0.0005968088999726 0.0024164244761899 0.0146338936924203 0.0003286021100258 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 4 6 2.0719030355602435 0.0382744848323288 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.004624601375411 0.0005968088999726 0.0024164244761899 0.0146338936924203 0.0003286021100258 +Guanylate kinase-like domain [IPR008144] 3 5 2.071010991447226 0.0383577688996716 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 1.0 1.0 1.0 0.3058660732099017 0.0048822579474643 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 3 5 2.071010991447226 0.0383577688996716 2.9975728155339807 6.963592233009709 0.5006632403339694 0.4738825144563896 2.043814711463587 1.6869386038453082 0.907662015536667 0.3076020117251588 1.0 1.0 1.0 0.3547863423381785 0.0097510399506001 +Phospholipid/glycerol acyltransferase [IPR002123] 3 5 2.0623568046617664 0.0391737785591121 2.4611650485436893 6.109223300970874 0.4541526786138767 0.3733328307275969 1.647577392422315 1.6678607828333205 1.200305691546449 0.3080828121567173 1.0 1.0 1.0 0.3225700131084155 0.0062633876942655 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5cec6a488cf8bb6aed27fc6bb16c886aab5396c1 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 2406, + "title": "Average number of proteins per term", + "value": 2.117206982543641 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..aed66d6b42cb304b15ebde9ab263cc83846f3994 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6c1c9d17901c9a462dc35bf7038ce37bbf3e4a91 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,211 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Reticulon [IPR003388] 0.9921708185053386 2.952299165935488 0.0031541717600862 0.9995000142136176 0.0674277867868435 2 Q9NQC3 1 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.99993471450197 0.0674277867868435 4 P07437,Q9BVA1,P68371 3 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.99993471450197 0.0674277867868435 4 P07437,Q9BVA1,P68371 3 +FAD linked oxidase, N-terminal [IPR006094] 0.964768683274024 2.843220239207112 0.0044660197779802 0.9999789647193782 0.0674277867868435 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.964768683274024 2.843220239207112 0.0044660197779802 0.9999789647193782 0.0674277867868435 2 Q15392 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9565836298932396 2.8103473069245903 0.0049488065043599 0.9999934522449588 0.0674277867868435 2 Q15629 1 +Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936] 0.9305785274703232 2.702333858277699 0.0068854586153468 0.9999999396865236 0.0674277867868435 3 Q9Y282 1 +Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542] 0.9305785274703232 2.702333858277699 0.0068854586153468 0.9999999396865236 0.0674277867868435 3 Q9Y282 1 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.9227758007117488 2.673124551158895 0.007514834341864 0.9999999868779316 0.0674277867868435 2 Q15418 1 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.9220640569395052 2.6702104217010953 0.0075803725728831 0.9999999888056268 0.0674277867868435 2 Q32P28 1 +Zinc finger, CHHC-type [IPR012996] 0.9216803132787464 2.665801083791098 0.0076805122596301 0.9999999912187164 0.0674277867868435 3 P31943,P52597 2 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9091556822230116 2.6094504570171084 0.0090687776771443 0.999999999697524 0.0674277867868435 5 O43169,O00264,O15173,Q8WUJ1 4 +GMP phosphodiesterase, delta subunit [IPR008015] 0.9049483802064882 2.596659192991696 0.0094135273372968 0.9999999998690524 0.0674277867868435 3 Q13432,A6NIH7 2 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.9047712671170594 2.595924167163269 0.0094336883196908 0.9999999998753104 0.0674277867868435 3 P52888 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.8996084015663983 2.5744691000518314 0.0100394053649566 0.9999999999713788 0.0692221033014298 3 Q9ULX6,O43823 2 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8971530249110313 2.567552117186184 0.0102419392098433 0.999999999982506 0.0692221033014298 2 Q7L576 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8946619217081851 2.5572149225204557 0.0105514003660358 0.999999999991756 0.0697384572486567 2 O60506 1 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.8854092526690398 2.5187053105563475 0.0117787191181544 0.999999999999584 0.0719767981810884 2 P51114 1 +LEM-like domain [IPR013146] 0.8846975088967977 2.515735557122162 0.0118784270730039 0.9999999999996736 0.0720348473706707 2 P42167 1 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.8740213523131766 2.471060727624604 0.0134712940253902 0.9999999999999932 0.0744840248494142 2 O15254 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8701067615658373 2.454619457232606 0.0141033797213649 0.9999999999999986 0.0754060702435648 2 Q9NVI7 1 +RBM1CTR [IPR012604] 0.8619217081850542 2.420137081810819 0.0155146572238071 1.0 0.0776962901518074 2 P38159 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8394446422214354 2.3202786677099696 0.0203258073456831 1.0 0.0827477030012074 3 P01889,P10321 2 +MHC class I, alpha chain, C-terminal [IPR010579] 0.8394446422214354 2.3202786677099696 0.0203258073456831 1.0 0.0827477030012074 3 P01889,P10321 2 +Marvel domain [IPR008253] 0.8370106761565923 2.3143125074613375 0.0206505862100145 1.0 0.0836698993812601 2 O43760 1 +CARG-binding factor, N-terminal [IPR012956] 0.8355871886121009 2.3082253836645292 0.0209866040479418 1.0 0.0844377413701472 2 Q99729 1 +KHDRBS, Qua1 domain [IPR032571] 0.8352313167259774 2.3067029264831937 0.0210713870034977 1.0 0.084496261884026 2 O75525 1 +Sam68, tyrosine-rich domain [IPR032335] 0.8352313167259774 2.3067029264831937 0.0210713870034977 1.0 0.084496261884026 2 O75525 1 +Zinc finger, CW-type [IPR011124] 0.8338078291815059 2.3006103928148507 0.021413663067896 1.0 0.0852914680610176 2 Q8NB78 1 +ERAP1-like C-terminal domain [IPR024571] 0.8305163243109857 2.2777722011716484 0.0227401534015598 1.0 0.0875719461411369 4 Q9UIQ6,P55786 2 +Methyltransferase type 11 [IPR013216] 0.8281138790035566 2.2761969811757385 0.0228342225268298 1.0 0.0875719461411369 2 Q8N6R0 1 +L27 domain, C-terminal [IPR014775] 0.8283475783475766 2.2683797711751628 0.0233060696342155 1.0 0.0879110598629028 4 O14936,Q14168,Q9NZW5 3 +L27 domain [IPR004172] 0.8283475783475766 2.2683797711751628 0.0233060696342155 1.0 0.0879110598629028 4 O14936,Q14168,Q9NZW5 3 +Ion transporter-like, CBS domain [IPR044751] 0.8103202846975106 2.1994591253592857 0.0278452924809453 1.0 0.0966873840358497 2 Q8NE01 1 +CNNM, transmembrane domain [IPR002550] 0.8103202846975106 2.1994591253592857 0.0278452924809453 1.0 0.0966873840358497 2 Q8NE01 1 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.8095407618369541 2.1910552028053876 0.0284477979390365 1.0 0.097354979552734 3 P20020,P16615 2 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.8095407618369541 2.1910552028053876 0.0284477979390365 1.0 0.097354979552734 3 P20020,P16615 2 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.7930565378443377 2.1141219392840016 0.0345048537988892 1.0 0.1042640205849911 4 P48735 1 +Nucleotidyl transferase domain [IPR005835] 0.7850533807829199 2.089335333365129 0.0366775478901686 1.0 0.1073554503938512 2 Q96IJ6 1 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7854626481670466 2.0719030355602435 0.0382744848323288 1.0 0.1089558407161945 6 P09960,Q9NZ08,Q9UIQ6,P55786 4 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7854626481670466 2.0719030355602435 0.0382744848323288 1.0 0.1089558407161945 6 P09960,Q9NZ08,Q9UIQ6,P55786 4 +Guanylate kinase-like domain [IPR008144] 0.784341146535358 2.071010991447226 0.0383577688996716 1.0 0.1089558407161945 5 O14936,Q14168,Q9NZW5 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.784341146535358 2.071010991447226 0.0383577688996716 1.0 0.1089558407161945 5 O14936,Q14168,Q9NZW5 3 +FAD dependent oxidoreductase [IPR006076] 0.7814168743325223 2.067783115442334 0.0386604221029063 1.0 0.1089558407161945 3 P43304,Q96CU9 2 +Phospholipid/glycerol acyltransferase [IPR002123] 0.7823964319507879 2.0623568046617664 0.0391737785591121 1.0 0.1095494860548001 5 Q8NF37,O15228,Q99943 3 +MHC class I-like antigen recognition-like [IPR011161] 0.7759971509971415 2.0386036687360183 0.0414895987924042 1.0 0.113699493332728 4 P01889,P04439,P10321 3 +Immunoglobulin C1-set [IPR003597] 0.7759971509971415 2.0386036687360183 0.0414895987924042 1.0 0.113699493332728 4 P01889,P04439,P10321 3 +Tim44-like domain [IPR007379] 0.7729537366548063 2.0361239505475774 0.0417379102926118 1.0 0.1141152410954819 2 O43615 1 +PTB/PI domain [IPR006020] 0.7737090549671737 2.0337069612753953 0.0419811498760587 1.0 0.1145200074850309 3 Q9UKG1 1 +Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.7625502358688186 1.9841547932454071 0.0472385863902424 1.0 0.1230247913028024 3 Q06124 1 +Dynamin, GTPase domain [IPR001401] 0.760876236748181 1.976698989064151 0.0480756651574729 1.0 0.1243763982461074 3 O60313 1 +PITH domain [IPR010400] 0.7551601423487577 1.9573203802565473 0.0503098128476318 1.0 0.126558753878156 2 O43396 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.7526690391459232 1.9462361348879016 0.051626381188762 1.0 0.1285205453579767 2 Q92945 1 +Protein kinase, C-terminal [IPR017892] 0.7520135775230343 1.9261214904663075 0.0540892058224757 1.0 0.1322547044805657 5 P51812,Q15418 2 +AWS domain [IPR006560] 0.746263345195737 1.9176761597923624 0.0551520864667938 1.0 0.1339010293028314 2 O96028 1 +GRAM domain [IPR004182] 0.7466280541169703 1.9130075983157877 0.0557470797294128 1.0 0.1343293480785064 3 Q66K14 1 +GOLD domain [IPR009038] 0.7409950931769254 1.8665963035256232 0.0619579841930555 1.0 0.140646458194063 8 P49755,Q15363,Q9Y3A6,O76054,Q9Y3B3 5 +Ariadne domain [IPR045840] 0.7213523131672634 1.8058366506872712 0.0709438587153989 1.0 0.1525388061387399 2 O95376 1 +Legume-like lectin [IPR005052] 0.7163701067615826 1.7833250276447823 0.0745334096050942 1.0 0.1572346979590094 2 Q12907 1 +Protein-tyrosine phosphatase, catalytic [IPR003595] 0.7161294244889109 1.762812653829845 0.0779320925164919 1.0 0.162482335004055 5 Q06124,Q9Y217 2 +Ataxin-2, C-terminal [IPR009818] 0.7129015222411115 1.7541098804933972 0.0794116809814151 1.0 0.1647107796907628 4 Q9BPZ3 1 +Acyltransferase, C-terminal domain [IPR032098] 0.7096085409252733 1.7526993542940958 0.0796536266153902 1.0 0.1649521008859293 2 Q92604 1 +Tyrosine-specific protein phosphatases domain [IPR000387] 0.7121669331045811 1.7507519174346036 0.0799886522259927 1.0 0.1649521008859293 4 Q06124 1 +ATP-sulfurylase PUA-like domain [IPR025980] 0.7074733096085392 1.7430105961312403 0.081331763933369 1.0 0.1652738378578428 2 O43252 1 +Sulphate adenylyltransferase [IPR002650] 0.7074733096085392 1.7430105961312403 0.081331763933369 1.0 0.1652738378578428 2 O43252 1 +Sulphate adenylyltransferase catalytic domain [IPR024951] 0.7074733096085392 1.7430105961312403 0.081331763933369 1.0 0.1652738378578428 2 O43252 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.706385621140973 1.7242897856868435 0.084655542319985 1.0 0.1693110846399701 4 Q32P28 1 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.7063856211409728 1.7242897856868435 0.084655542319985 1.0 0.1693110846399701 4 Q32P28 1 +Fxr1, tudor domain [IPR041560] 0.7020224742342613 1.7110358662180072 0.0870744920462542 1.0 0.1718631893874387 3 P51114 1 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7020224742342613 1.7110358662180072 0.0870744920462542 1.0 0.1718631893874387 3 P51114 1 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7020224742342613 1.7110358662180072 0.0870744920462542 1.0 0.1718631893874387 3 P51114 1 +Agenet-like domain [IPR008395] 0.7020224742342613 1.7110358662180072 0.0870744920462542 1.0 0.1718631893874387 3 P51114 1 +AGC-kinase, C-terminal [IPR000961] 0.699644351466514 1.677456360386551 0.0934532762039317 1.0 0.180044345362947 7 P51812,Q15418 2 +LEM domain [IPR003887] 0.6981294390557212 1.674013186240746 0.0941280078611652 1.0 0.1810327633205145 6 Q86XL3,P50402,P42167 3 +DNA-directed RNA polymerase, insert domain [IPR011262] 0.6889679715302486 1.658700992761141 0.0971760592580728 1.0 0.1845348055050696 2 O15160 1 +DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263] 0.6889679715302486 1.658700992761141 0.0971760592580728 1.0 0.1845348055050696 2 O15160 1 +SET domain [IPR001214] 0.6909710062047805 1.6407562039247767 0.1008480328435543 1.0 0.1889722484591836 6 Q03164,Q9H7B4 2 +Cold-shock (CSD) domain [IPR019844] 0.6814712533951122 1.6167597598849277 0.1059301486632366 1.0 0.195196279713092 3 P67809 1 +Post-SET domain [IPR003616] 0.6829997844156975 1.6166473593344612 0.1059544228201572 1.0 0.195196279713092 4 Q03164 1 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6704626334519559 1.5738151982153292 0.1155301793809298 1.0 0.2047848581065296 2 P51784 1 +Sec7 domain [IPR000904] 0.6701067615658353 1.5721774958542245 0.1159093929667776 1.0 0.2049066858766105 2 Q6DN90 1 +MOSC, N-terminal beta barrel [IPR005303] 0.669395017793593 1.568901517342829 0.1166708882801317 1.0 0.2050475947421453 2 Q5VT66 1 +Molybdenum cofactor sulfurase, C-terminal [IPR005302] 0.669395017793593 1.568901517342829 0.1166708882801317 1.0 0.2050475947421453 2 Q5VT66 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.6593489306613693 1.499653157996053 0.1337042701961508 1.0 0.2250947057042926 5 Q9HD20,P16615,P20020 3 +CAP Gly-rich domain [IPR000938] 0.6550373798504916 1.4945111552000412 0.1350420684595676 1.0 0.2263370586602594 3 Q99426,Q15813 2 +ABC transporter type 1, transmembrane domain [IPR011527] 0.6565183678245435 1.4936976034233036 0.1352546752286061 1.0 0.2264598111343259 4 O75027,P33527 2 +Alpha/beta hydrolase fold-1 [IPR000073] 0.6558120491629768 1.4904045261330887 0.1361179031541708 1.0 0.2272725017272276 4 P07099 1 +Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766] 0.6480427046263321 1.4702860428592943 0.1414842995306435 1.0 0.2329987848533391 2 Q9UJ83 1 +Thiamine pyrophosphate enzyme, central domain [IPR012000] 0.6480427046263321 1.4702860428592943 0.1414842995306435 1.0 0.2329987848533391 2 Q9UJ83 1 +Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001] 0.6480427046263321 1.4702860428592943 0.1414842995306435 1.0 0.2329987848533391 2 Q9UJ83 1 +RNA polymerase Rpb2, domain 4 [IPR007646] 0.6441281138790012 1.4521411520205625 0.1464623615124867 1.0 0.2375508760289875 2 Q9NW08 1 +RNA polymerase Rpb2, domain 5 [IPR007647] 0.6441281138790012 1.4521411520205625 0.1464623615124867 1.0 0.2375508760289875 2 Q9NW08 1 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.6316725978647652 1.3942900281641668 0.1632300409451281 1.0 0.2517646660816643 2 Q8WUM0 1 +Chromo domain subgroup [IPR017984] 0.6333609459539082 1.3935676063280278 0.1634482163007313 1.0 0.2517646660816643 3 P83916 1 +Chromo shadow domain [IPR008251] 0.6333609459539082 1.3935676063280278 0.1634482163007313 1.0 0.2517646660816643 3 P83916 1 +Myb domain [IPR017930] 0.6309534570239613 1.353668798071186 0.1758420669581391 1.0 0.2625351215902535 7 Q99543 1 +Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791] 0.622775800711755 1.3528708873543316 0.1760968814362002 1.0 0.2626714796872274 2 Q9NVE7 1 +Immunoglobulin-like domain [IPR007110] 0.6311673185329723 1.3420474658581636 0.1795806058498339 1.0 0.2660535330509239 10 P35613,P01889,P04439,P10321 4 +EF-hand, Ca insensitive [IPR014837] 0.6214170548118115 1.3377351699223774 0.1809827819031446 1.0 0.2676364924763159 3 O43707 1 +PB1 domain [IPR000270] 0.6128113879003655 1.3064024791307378 0.1914157232232096 1.0 0.2776047197559026 2 Q13501 1 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.6198233373617944 1.275251858423034 0.2022201113922632 1.0 0.2886788933027315 15 Q96K76,Q8TEY7,P40818 3 +Ubiquitin specific protease domain [IPR028889] 0.6198233373617944 1.275251858423034 0.2022201113922632 1.0 0.2886788933027315 15 Q96K76,Q8TEY7,P40818 3 +NOPS [IPR012975] 0.6063798774960554 1.2672865053577396 0.2050528639641964 1.0 0.2906485814808111 3 Q15233 1 +Rab-GTPase-TBC domain [IPR000195] 0.6015167576229822 1.2193095360792905 0.2227267305727001 1.0 0.306392517871879 6 Q66K14 1 +Major facilitator superfamily domain [IPR020846] 0.5999365093641392 1.211803298817775 0.2255876852612828 1.0 0.3090910995094797 6 Q8NHS3,Q14728,Q5SR56 3 +Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598] 0.5918149466192159 1.2083001048839015 0.2269318481464353 1.0 0.3102261515001837 2 Q9UNQ2 1 +START domain [IPR002913] 0.5896797153024851 1.1983155164208306 0.2307942082211522 1.0 0.3133695626298489 2 Q9NQZ5 1 +Glycosyltransferase 2-like [IPR001173] 0.5841856179526821 1.1453027020079436 0.2520837870843444 1.0 0.3326780588464016 5 Q86SF2,Q9Y673,Q10472 3 +N-acetylgalactosaminyltransferase [IPR045885] 0.5790064061809759 1.138822531832129 0.2547771819803508 1.0 0.3353650997168132 3 Q10472 1 +Sec63 domain [IPR004179] 0.5789950491769846 1.1387692294523135 0.2547994190699645 1.0 0.3353650997168132 3 Q9UGP8 1 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.5857906066030293 1.1271093170829636 0.2596962645612386 1.0 0.3397657490670691 9 O15254,Q709F0,Q92947 3 +CBS domain [IPR000644] 0.5761025890142477 1.1070699262776584 0.2682636967539946 1.0 0.345341067089412 5 Q8NE01 1 +Exoribonuclease, phosphorolytic domain 1 [IPR001247] 0.5765802134903752 1.100853301914188 0.2709605090097038 1.0 0.3482537311310617 6 Q96B26,Q9NQT4 2 +Cold-shock protein, DNA-binding [IPR002059] 0.5707958715367148 1.0909675309971414 0.2752871699002575 1.0 0.3512900128505768 4 P67809 1 +Cold shock domain [IPR011129] 0.5707958715367148 1.0909675309971414 0.2752871699002575 1.0 0.3512900128505768 4 P67809 1 +PABP, RNA recognition motif 2 [IPR045305] 0.557295373665478 1.0469775189862296 0.2951099468432363 1.0 0.3674870416441775 2 Q13310 1 +Phox homology [IPR001683] 0.5600589610921787 1.0091840432735804 0.3128863777869028 1.0 0.3800124305680405 8 Q96L92 1 +EF hand associated, type-2 [IPR013567] 0.5473309608540867 1.0005475411126368 0.3170456025665835 1.0 0.3814047766026918 2 Q8IXI1 1 +MIRO domain [IPR020860] 0.5473309608540867 1.0005475411126368 0.3170456025665835 1.0 0.3814047766026918 2 Q8IXI1 1 +EF hand associated, type-1 [IPR013566] 0.5473309608540867 1.0005475411126368 0.3170456025665835 1.0 0.3814047766026918 2 Q8IXI1 1 +Exoribonuclease, phosphorolytic domain 2 [IPR015847] 0.5508698606876694 0.987982235754188 0.323161348285957 1.0 0.3875788131734518 5 Q9NQT4 1 +SCP2 sterol-binding domain [IPR003033] 0.5339978640085463 0.928331221457414 0.3532357835096231 1.0 0.4113675194211778 3 P51659,Q6YN16 2 +Myosin tail [IPR002928] 0.5306049822064037 0.9229187597524304 0.3560495435426212 1.0 0.4132453751809019 2 P35580 1 +EB1, C-terminal [IPR004953] 0.5266903914590771 0.9048238348044066 0.3655587224581165 1.0 0.4208298020259465 2 Q15555 1 +RNA recognition motif domain, eukaryote [IPR003954] 0.540356394422123 0.8878045862476287 0.374645875513157 1.0 0.4267982843203862 13 Q96E39,Q14011,P31483,Q9UHX1,P38159 5 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.5185053380782945 0.8671017700696871 0.3858862508486311 1.0 0.4356838665142217 2 P14866 1 +DnaJ domain [IPR001623] 0.5352614609881722 0.849020538049726 0.3958698641396823 1.0 0.4434704077284092 17 Q13217,Q9UBS4,Q9UGP8,Q99543,Q8IXB1,Q96KC8,O14976 7 +MoaB/Mog domain [IPR001453] 0.512455516014225 0.8393317747134904 0.4012831573109654 1.0 0.4473991086608817 2 Q9NQX3 1 +Immunoglobulin I-set [IPR013098] 0.5087219651121389 0.8116267641887207 0.4170058290139971 1.0 0.4602367085356316 3 Q8WX93,P10586 2 +OCRE domain [IPR041591] 0.5017793594305955 0.790598090460686 0.4291785615031731 1.0 0.4697923653214897 2 P98175 1 +Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.5021627945805683 0.7435375084332095 0.4571563215343865 1.0 0.4979258078821793 7 Q8N8N7,Q8N4Q0 2 +AMP-binding enzyme, C-terminal domain [IPR025110] 0.4909220363118624 0.7306550188307073 0.4649898969220771 1.0 0.5062288199070215 3 P33121,Q4G176 2 +SANT domain [IPR017884] 0.5022975539710777 0.7293182924787239 0.4658069852788626 1.0 0.5068890124744204 9 Q99543 1 +Glutaredoxin, PICOT-like [IPR033658] 0.4879003558718858 0.7278683870683094 0.4666941565712506 1.0 0.5076248375725266 2 Q86SX6 1 +EF-hand domain [IPR002048] 0.4973106882736101 0.7237457790116683 0.4692218225474773 1.0 0.5101435630588479 40 Q96AY3,O43852,Q66K14,Q8IYU8,Q14257,Q8NF37,P80303,Q15293,Q9UJS0,Q9BPX6 10 +Tyrosine-protein kinase, catalytic domain [IPR020635] 0.4864768683274062 0.7214805392021257 0.4706139098619286 1.0 0.5114259562456189 2 P08069 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.4832740213523034 0.7071422786915822 0.4794780645583558 1.0 0.5196505510483802 2 P42285 1 +rRNA-processing arch domain [IPR025696] 0.4832740213523034 0.7071422786915822 0.4794780645583558 1.0 0.5196505510483802 2 P42285 1 +ZU5 domain [IPR000906] 0.482562277580071 0.7039626427882043 0.4814560383690551 1.0 0.5215593103628756 2 Q12955 1 +Kinesin-like KIF1-type [IPR022140] 0.481850533807831 0.7007854792123897 0.4834369013821371 1.0 0.5232340012260107 2 O60333 1 +C2 domain [IPR000008] 0.4946383903441283 0.6938387738783771 0.4877833235127475 1.0 0.5269899759190259 9 Q96PU5,Q99829,Q96J02 3 +Kinesin-like [IPR022164] 0.4820220719117141 0.6906736109259743 0.4897706766110867 1.0 0.5286622915775482 3 O60333,Q9Y3P9 2 +Kinesin-associated [IPR032405] 0.4820220719117024 0.6906736109259214 0.48977067661112 1.0 0.5286622915775482 3 O60333,Q15058 2 +Zinc finger, RanBP2-type [IPR001876] 0.4931291012451886 0.6868805674901803 0.4921579935298303 1.0 0.5307629459582124 9 Q92804 1 +14-3-3 domain [IPR023410] 0.4878831076265084 0.6864183575243016 0.4924493315457794 1.0 0.5308391987899397 6 Q04917,P61981,P31946,P63104,P62258 5 +RNA polymerase, beta subunit, protrusion [IPR007644] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5308442322891799 3 P30876,Q9NW08 2 +RNA polymerase Rpb2, domain 7 [IPR007641] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5308442322891799 3 P30876,Q9NW08 2 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5308442322891799 3 P30876,Q9NW08 2 +RNA polymerase Rpb2, domain 2 [IPR007642] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5308442322891799 3 P30876,Q9NW08 2 +RNA polymerase Rpb2, domain 3 [IPR007645] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5308442322891799 3 P30876,Q9NW08 2 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.4768683274021351 0.6786167816550678 0.4973807068922653 1.0 0.5344787765890087 2 O15344 1 +G-protein, beta subunit [IPR001632] 0.4722419928825625 0.6581492493509211 0.5104422321171502 1.0 0.5472923397833617 2 Q9NVX2 1 +Sterile alpha motif domain [IPR001660] 0.4766468301581773 0.635867356900496 0.5248628805608786 1.0 0.5622529343853401 6 Q9Y3Z3 1 +Cyclic nucleotide-binding domain [IPR000595] 0.4693732193732339 0.6239227072532412 0.532678346907868 1.0 0.5691048413234149 4 Q9Y4G8,P13861,Q6P4Q7 3 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.471850234392259 0.5978820706914657 0.5499186239617657 1.0 0.5866220153595681 8 Q96AY3,P62942 2 +Thioredoxin domain [IPR013766] 0.4846341261170191 0.586349926513944 0.5576403865541497 1.0 0.5944200872185523 23 Q6ZRP7,Q9Y320,O43819,Q8IXB1,Q9H3N1,Q9H1E5,O43396 7 +PDZ domain [IPR001478] 0.4775914616109403 0.5836103410914214 0.5594825011828817 1.0 0.5956260609938112 14 O14936,Q96L92,Q9NZW5,Q14168 4 +Helicase/UvrB, N-terminal [IPR006935] 0.4516014234875458 0.5684221092381678 0.5697483813031488 1.0 0.6062868666144962 2 P19447 1 +DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.4519230769230978 0.5480546641696566 0.5836543687243045 1.0 0.6199878194925724 4 P42694,O60306,Q9HCE1 3 +Exosome complex component, N-terminal domain [IPR025721] 0.4437722419928843 0.5351714090951112 0.592531334720293 1.0 0.6285848286318452 2 Q13868 1 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.44764957264957 0.5298175865070451 0.5962384106428225 1.0 0.6322387025150422 4 P05771,Q13464,Q9H0H5 3 +Glutathione S-transferase, N-terminal [IPR004045] 0.4543414797640404 0.5291662502143393 0.5966901267388309 1.0 0.632438962525827 7 Q8TB36,Q9H7Z7 2 +ARID DNA-binding domain [IPR001606] 0.4410822356710611 0.5128199137553064 0.6080772985563916 1.0 0.6433746615332798 3 O14497,Q8IVW6 2 +BAT2, N-terminal [IPR009738] 0.4352313167259807 0.4994677981231042 0.6174498669533777 1.0 0.652430557703042 2 Q9Y520 1 +HECT domain [IPR000569] 0.4458855072614579 0.4844801085512557 0.6280451778679694 1.0 0.6630437463581985 8 Q96PU5,Q96J02 2 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.4295373665480439 0.476024512947478 0.6340569143459334 1.0 0.6685104890080262 2 Q9BSJ2 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.4295373665480439 0.476024512947478 0.6340569143459334 1.0 0.6685104890080262 2 Q9BSJ2 1 +Peptidase M16, middle/third domain [IPR032632] 0.4209964412811361 0.441444527525516 0.6588912124902542 1.0 0.6925697934694415 2 O43847 1 +K Homology domain, type 1 [IPR004088] 0.4549416945348454 0.4395514473228314 0.6602620125134038 1.0 0.6934048023165645 25 P51116,Q96I24,P61978,Q07666,O75525,P51114,O75179,Q92945 8 +Brix domain [IPR007109] 0.4271464196651117 0.4340614107914093 0.6642438468931955 1.0 0.6969780617640768 5 Q96G21,Q8TDN6,Q9NQ55,Q9H9Y2 4 +K Homology domain [IPR004087] 0.4511600886099293 0.4234451883569107 0.671970481254708 1.0 0.7047781071921655 24 P51116,Q96I24,P61978,Q07666,O75525,P51114,O75179,Q92945 8 +Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075] 0.428752171074678 0.4215092780764102 0.6733832376097151 1.0 0.7056446296554767 7 Q92947 1 +Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786] 0.428752171074678 0.4215092780764102 0.6733832376097151 1.0 0.7056446296554767 7 Q92947 1 +Syntaxin, N-terminal domain [IPR006011] 0.4175863296546827 0.4168753860093724 0.6767695581258417 1.0 0.7082677498263485 3 O15400,Q86Y82 2 +NLE [IPR012972] 0.4106761565836286 0.4006796089235997 0.6886560255013401 1.0 0.7191434016303057 2 Q9NVX2 1 +PurM-like, N-terminal domain [IPR016188] 0.4039145907473349 0.374628949393482 0.7079364399640211 1.0 0.737357175131357 2 P49903 1 +PurM-like, C-terminal domain [IPR010918] 0.4040583837664668 0.3643089545359495 0.7156273139093632 1.0 0.7447228880907992 3 P49903,O15067 2 +Protein of unknown function DUF3715 [IPR022188] 0.3989323843416422 0.3557901648363981 0.7219977151046608 1.0 0.7497309031255132 2 Q9UK61 1 +RNA recognition motif domain [IPR000504] 0.2763092876689826 0.3362250794889633 0.7367011419870217 1.0 0.764009891215851 112 P23588,Q96E39,P62995,Q15233,O60506,P51991,P22626,Q92804,P52597,P31483,Q14011,O43390,P31942,O14979,Q96PK6,Q9BWF3,Q13242,Q99729,Q9UHX1,Q01844,Q01085,P31943,Q14103,P55795,P07910,Q16629,P35637,P38159,Q07955,Q9Y6M1 30 +SANT/Myb domain [IPR001005] 0.4153440116787637 0.3351297543632125 0.7375272086330702 1.0 0.7645370374714204 11 Q99543 1 +Band 7 domain [IPR001107] 0.4035650623885906 0.3224463101450049 0.7471146056202917 1.0 0.7738087564022479 7 Q14254,O75955,O94905,O75477,Q99623,Q9UJZ1 6 +Peptidase M16, C-terminal [IPR007863] 0.4011783024968606 0.3134788205919768 0.7539169091174696 1.0 0.7798469833777436 7 O43847,P22695,Q5JRX3 3 +Peptidase M16, N-terminal [IPR011765] 0.4011783024968606 0.3134788205919768 0.7539169091174696 1.0 0.7798469833777436 7 O43847,P22695,Q5JRX3 3 +Heat shock chaperonin-binding [IPR006636] 0.3812744749021035 0.2810908700199173 0.778640703651559 1.0 0.8037663198671436 3 P54727,Q9NRR5 2 +GYF domain [IPR003169] 0.3779359430605064 0.2800494005262378 0.7794396044451428 1.0 0.8041731081882563 2 O95400 1 +Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0.3854649091556799 0.2752895167009036 0.7830938179017721 1.0 0.8064445249746239 5 Q9P2J5,Q15031,P41252,Q9NSE4 4 +Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0.3854649091556799 0.2752895167009036 0.7830938179017721 1.0 0.8064445249746239 5 Q9P2J5,Q15031,P41252,Q9NSE4 4 +NAD-dependent epimerase/dehydratase [IPR001509] 0.3592025631897499 0.2078933703682952 0.8353122257663497 1.0 0.8544903125824138 3 Q9NRG7,Q13630 2 +MCM N-terminal domain [IPR027925] 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.8653741877393618 6 Q14566 1 +MCM domain [IPR001208] 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.8653741877393618 6 Q14566 1 +MCM OB domain [IPR033762] 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.8653741877393618 6 Q14566 1 +MCM, AAA-lid domain [IPR041562] 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.8653741877393618 6 Q14566 1 +RasGAP protein, C-terminal [IPR000593] 0.3473309608540923 0.1818297775863136 0.8557163149153915 1.0 0.8705511432077936 2 P46940 1 +Immunoglobulin subtype 2 [IPR003598] 0.3516209476309119 0.1652957292492933 0.8687112201491596 1.0 0.8819068336197797 5 P35613,Q8WX93,Q13308,P10586 4 +Immunoglobulin subtype [IPR003599] 0.3516209476309119 0.1652957292492933 0.8687112201491596 1.0 0.8819068336197797 5 P35613,Q8WX93,Q13308,P10586 4 +Nuclear transport factor 2 domain [IPR002075] 0.3436609686609663 0.1517668751825407 0.8793708092144155 1.0 0.8904739759974257 4 Q9UN86,Q13283,Q9UBU9 3 +Nuclear transport factor 2, eukaryote [IPR018222] 0.3436609686609663 0.1517668751825407 0.8793708092144155 1.0 0.8904739759974257 4 Q9UN86,Q13283,Q9UBU9 3 +TRIAD supradomain [IPR044066] 0.3387076762528525 0.1474420671700871 0.8827831035331037 1.0 0.8928020794874517 3 O95376 1 +IBR domain [IPR002867] 0.3387076762528525 0.1474420671700871 0.8827831035331037 1.0 0.8928020794874517 3 O95376 1 +Dynamin, N-terminal [IPR045063] 0.3467623642240403 0.1334669889627206 0.8938240696579687 1.0 0.902314524786875 7 O00429,O60313 2 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.3467623642240403 0.1334669889627206 0.8938240696579687 1.0 0.902314524786875 7 O00429,O60313 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.3319088319088322 0.1198518275280168 0.904600525370096 1.0 0.9118009484878304 4 P08069,P41240,Q13308 3 +Sirtuin family, catalytic core domain [IPR026590] 0.3227758007117477 0.1151399233203666 0.9083342160816752 1.0 0.9151809564038988 2 Q8IXJ6 1 +La-type HTH domain [IPR006630] 0.3327161050928851 0.1128395820067315 0.9101577368255158 1.0 0.916634372039427 5 Q71RC2 1 +ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650] 0.3156583629893312 0.0980018935642423 0.9219307897609116 1.0 0.9281027113660056 2 Q96I99 1 +Disulphide isomerase [IPR005788] 0.320270751692191 0.0821503003037964 0.93452719440402 1.0 0.9399968351739434 5 P07237,Q8NBS9,P30101,P13667 4 +Glutathione S-transferase, C-terminal-like [IPR010987] 0.3220328981148209 0.0396524458804053 0.9683702145231488 1.0 0.9736308968419122 11 Q8TB36,Q9H7Z7 2 +SPRY-associated [IPR006574] 0.2938034188034187 0.0353827556423033 0.9717745351057748 1.0 0.9762378001939432 4 P19474,O15344,Q14258 3 +Butyrophylin-like, SPRY domain [IPR003879] 0.2938034188034187 0.0353827556423033 0.9717745351057748 1.0 0.9762378001939432 4 P19474,O15344,Q14258 3 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.2853580334877041 0.0129613651092361 0.989658616446766 1.0 0.9933744810892444 5 P55039,A4D1E9,Q9Y295,Q9NTK5 4 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7fd92f0cc45ab04fe115459b037dcb04abe6c22e --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3, C-terminal [IPR007177]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase alpha 1 catalytic subunit, C-terminal [IPR039137]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "APPL1, BAR domain [IPR037929]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acetyl-coenzyme A synthetase, N-terminal domain [IPR032387]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein ClpS, core [IPR003769]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Aurora-A binding [IPR015128]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BCL-6 corepressor, PCGF1 binding domain [IPR032365]", "BCL-6 corepressor, non-ankyrin-repeat domain [IPR031628]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BEACH domain [IPR000409]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BR140-related, PWWD domain [IPR035502]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BRPF2, PHD domain [IPR042009]", "BRPF2, ePHD domain [IPR042004]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-mannosidase, Ig-fold domain [IPR041625]", "Beta-trefoil DNA-binding domain [IPR015350]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bms1/Tsr1-type G domain [IPR030387]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "COG complex component, COG2, C-terminal [IPR024603]", "COMM domain [IPR017920]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CPL domain [IPR012959]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRAL/TRIO, N-terminal domain [IPR011074]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cation/H+ exchanger [IPR006153]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomal CEP44 domain [IPR029157]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Chromosome segregation protein Spc25, C-terminal [IPR013255]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Conserved oligomeric Golgi complex, subunit 2, N-terminal [IPR024602]", "Conserved oligomeric Golgi complex, subunit 4 [IPR013167]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DNAJC17, RNA recognition motif [IPR034254]", "DOCKER domain [IPR027357]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyl-phosphate beta-glucosyltransferase [IPR035518]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERCC4 domain [IPR006166]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enhancer of polycomb-like, N-terminal [IPR019542]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FMP27, C-terminal [IPR019443]", "FMP27, GFWDK domain [IPR019441]", "FMP27, N-terminal [IPR019439]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Fascin domain [IPR022768]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Furin-like cysteine-rich domain [IPR006211]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gasdermin, PUB domain [IPR041263]", "Gasdermin, pore forming domain [IPR040460]", "Gcp-like domain [IPR000905]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HBS1-like protein, N-terminal [IPR015033]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone chaperone domain CHZ [IPR019098]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IQ motif and SEC7 domain-containing protein, PH domain [IPR033742]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Interferon gamma receptor, poxvirus/mammal [IPR021126]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KASH domain [IPR012315]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Large proline-rich protein BAG6 [IPR021925]", "Lariat debranching enzyme, C-terminal [IPR007708]", "Lariat debranching enzyme, N-terminal metallophosphatase domain [IPR041816]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "LsmAD domain [IPR009604]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Macro domain [IPR002589]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannosidase Ig/CBM-like domain [IPR041447]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Morc, S5 domain 2-like [IPR041006]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH:ubiquinone oxidoreductase intermediate-associated protein 30 [IPR013857]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal [IPR018849]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, C-terminal [IPR032630]", "P-type ATPase, N-terminal [IPR032631]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA1, UBA-like autoinhibitory domain [IPR028797]", "PRKCBP1, PHD finger [IPR044075]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C1A, propeptide [IPR012599]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor 38, C-terminal [IPR024767]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "Quinolinate phosphoribosyl transferase, C-terminal [IPR002638]", "Quinolinate phosphoribosyl transferase, N-terminal [IPR022412]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM8, RNA recognition motif [IPR033744]", "RBP-J/Cbf11/Cbf12, DNA binding [IPR015351]", "RBP-Jkappa, IPT domain [IPR038007]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING finger protein 219, RING finger [IPR035691]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Receptor L-domain [IPR000494]", "Redoxin [IPR013740]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rhodanese-like domain [IPR001763]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SNAP-25 domain [IPR000928]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Sequestosome-1, PB1 domain [IPR034866]", "Sequestosome-1, UBA domain [IPR033741]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine proteases, trypsin domain [IPR001254]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein Lsm4 [IPR034101]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TANK binding kinase 1, ubiquitin-like domain [IPR041087]", "TANK-binding kinase 1, coiled-coil domain 1 [IPR041309]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBC1D8B, PH-GRAM domain 1 [IPR036012]", "TBC1D8B, PH-GRAM domain 2 [IPR036015]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIID subunit TAF5, NTD2 domain [IPR007582]", "TGS [IPR004095]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim44-like domain [IPR007379]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uracil-DNA glycosylase-like [IPR005122]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS9 domain [IPR003123]", "VWA N-terminal [IPR013608]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region [IPR013680]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WIBG, Mago-binding [IPR015362]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZO-1, SH3 domain [IPR035597]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA splicing factor Cwf21 domain [IPR013170]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNase Z endonuclease [IPR027794]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "APLP2", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8A", "ARMCX3", "ARMT1", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATXN10", "ATXN2L", "AUP1", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BCAP31", "BCOR", "BCS1L", "BIRC6", "BLVRA", "BLVRB", "BMS1", "BOP1", "BPTF", "BRD1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "C11orf58", "C1orf35", "CACNA2D1", "CACYBP", "CAD", "CALU", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CENPF", "CEP170", "CEP44", "CEP55", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP2L", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLTC", "CLUH", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNPY2", "COA3", "COG2", "COG4", "COIL", "COLEC12", "COMMD4", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CRKL", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNBL1", "CTPS1", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWF19L1", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCTN1", "DCUN1D1", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DFFA", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DPH5", "DPM1", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "EARS2", "ECE1", "ECI2", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM208A", "FAM208B", "FAM49B", "FAM8A1", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBXO7", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPS", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPB11", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INCENP", "INTS1", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPK1", "IVD", "IWS1", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA1147", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIN", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LRSAM1", "LSM12", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MANBA", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARS", "MAT2A", "MAT2B", "MATR3", "MBD3", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "METTL13", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD8", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPHOSPH8", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYADM", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCL", "NCLN", "NCSTN", "NDUFA10", "NDUFA9", "NDUFAF1", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDZD11", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITRM1", "PKM", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POR", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS7", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RAVER1", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RSF1", "RSL24D1", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL2", "SDAD1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A4", "SLC2A1", "SLC38A1", "SLC3A2", "SLC7A1", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPC25", "SPECC1", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STOML2", "STRBP", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "TIA1", "TIAL1", "TIMM44", "TIMM50", "TJP1", "TKT", "TLN1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TSR3", "TST", "TSTA3", "TTC4", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL5", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "URB2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VCP", "VIM", "VIRMA", "VPS16", "VPS29", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YBX3", "YKT6", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ACAD11", "ACOX3", "ACSF3", "ACSL1", "ACTN4", "AGPAT1", "AKAP8", "AKAP8L", "ALG5", "ANK3", "ANKLE2", "ANKRD17", "APPL1", "AQR", "ARID1A", "ARID3B", "ARIH2", "ATAD3A", "ATP13A1", "ATP2A2", "ATP2B1", "BRIX1", "BSG", "CALU", "CASK", "CBX1", "CD2BP2", "CIRBP", "CNNM3", "CNNM4", "CPNE1", "CSK", "CYB5B", "CYB5D2", "CYFIP1", "DHCR24", "DIMT1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNM1L", "DRG1", "DRG2", "EIF4B", "EMD", "EPHX1", "ERAP1", "ERCC3", "ERGIC3", "ERLIN1", "ERLIN2", "EWSR1", "EXOSC2", "EXOSC5", "EXOSC8", "FAM208A", "FKBP10", "FKBP1A", "FLOT1", "FLOT2", "FOXRED1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "GAK", "GALNT1", "GALNT7", "GCDH", "GDAP1", "GLRX5", "GMPPA", "GNPAT", "GPD2", "GPHN", "GTPBP10", "HACL1", "HELZ", "HLA-A", "HLA-B", "HLA-C", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPR", "HSD17B4", "HSDL2", "IARS", "IARS2", "IDH2", "IGF1R", "IGF2BP2", "IMP4", "IQGAP1", "IQSEC1", "ITCH", "KDM1B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF14", "KIF1B", "KMT2A", "LARP4", "LARS", "LARS2", "LMAN2", "LNPEP", "LPCAT1", "LPGAT1", "LTA4H", "MAPRE2", "MARC1", "MCM6", "METTL13", "MFSD10", "MFSD14B", "MFSD8", "MICU1", "MICU2", "MID1", "MOV10", "MPP2", "MPP6", "MTMR6", "MYH10", "NEDD4L", "NLE1", "NONO", "NPEPPS", "NRDC", "NSD2", "NUCB2", "NUP133", "NXF1", "OLA1", "OPA1", "P3H1", "P4HB", "PABPC4", "PAIP2", "PALLD", "PANK4", "PAPSS1", "PDIA3", "PDIA4", "PFAS", "PGRMC1", "PGRMC2", "PHB2", "PITRM1", "POLR1C", "POLR2B", "POLR3B", "PPAN", "PRKAR2A", "PRKCB", "PRRC2C", "PTGES2", "PTGR2", "PTK7", "PTPN11", "PTPRF", "PUF60", "QSOX2", "RABGAP1", "RACGAP1", "RAD23B", "RAPGEF2", "RBM10", "RBM14", "RBM4", "RBMX", "RBMXL1", "RCN1", "RCN2", "RHOT2", "ROCK1", "RPF1", "RPS6KA1", "RPS6KA3", "RTN4", "SAMHD1", "SCO2", "SDR39U1", "SEC14L2", "SEC63", "SEPHS1", "SIRT2", "SKIV2L2", "SLC25A13", "SMYD3", "SNX27", "SQSTM1", "SRSF1", "SRSF7", "SRSF9", "STARD7", "STOML2", "STX12", "STX7", "SUCLG2", "SYNCRIP", "SYNGR2", "TAF15", "TBC1D9B", "TBCB", "TBCE", "THOP1", "TIA1", "TIAL1", "TIMM44", "TMED10", "TMED2", "TMED5", "TMED7", "TMPO", "TMX1", "TMX2", "TMX4", "TRA2B", "TRAM1", "TRIM21", "TRIM25", "TSTA3", "TUBB", "TUBB2B", "TUBB4B", "TUBGCP2", "TXNDC5", "TXNL1", "UBQLN4", "UNC119", "UNC119B", "UQCRC2", "USP11", "USP33", "USP47", "USP8", "YBX1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZADH2"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..18feebdc8be79f3f7f761f1457b29593a5bed697 --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]", "1": "14-3-3 protein [IPR000308]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..92fc9b2d81991fc45e8e6ef4a638858abaa3403e --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:379aec81bab55689bfcda5e907c36aa8f6ba49a0edd92bfc4b3d97017e9e3eab +size 133845 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9bd761e4e3f0ef72f1e3a8ded60d99ba8843c713 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fb7393b7e218bd6690833407590c708ddfe9bcb6739e0c0e4f7afd342d9ac9a +size 127624 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9f4e6a6f1d9ed316345ce8c63b920a70f3a0fcb0 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ad4988b029a59703cce86a8f0eaa6b88ecce46c302b45e542c025e9b41e37397 +size 499928 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a0f45ceb321822e902872969b2fb30c3052410e9 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Major facilitator superfamily [IPR011701] 4 6 2.442214805354076 0.0145974581558763 1.900485436893204 4.145631067961165 1.0239318262629833 0.2378354197978781 1.3191273068698348 1.552684909115802 1.329586452483978 0.2573287434106264 0.0397170539104867 1.0 0.2052107238795277 0.112413166150522 0.0052134507581354 +Proteasome B-type subunit [IPR023333] 3 7 2.1374938772718277 0.032557843183733 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0058945182768218 0.04159641685533 0.003087611696091 0.0010341818226167 0.0005688349419973 +Transmembrane emp24 domain-containing protein [IPR015720] 4 6 2.078052773310134 0.0377044987623718 2.6432038834951457 5.099514563106796 0.3626508447128717 0.2724944971681708 1.287119696753696 0.8431907483703972 1.4713835809049645 0.2794327521776852 1.0 1.0 1.0 1.0 1.3106068439724131e-05 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 4 6 2.0719030355602435 0.0382744848323288 2.121359223300971 5.466019417475728 1.4317001483019938 0.1783942022754649 1.021530403905949 0.5881604361499402 0.986353205880356 0.2226891741813114 0.004624601375411 0.0005968088999726 0.0024164244761899 0.0146338936924203 0.0003286021100258 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5eee36f30e1ff4bf3f366186f2843b92d45bed32 --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 2191, + "title": "Average number of proteins per term", + "value": 1.2752167959835692 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b7534e86aabc726ff481492710136a29fae096ff --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1308201a803974968148eda4bbfdfe516a5162be --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,98 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.999644128113879 2.981790711466718 0.0028656782806741 0.9981409965340328 0.0480632607295877 2 Q99595 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.980071174377224 2.9043181962964666 0.003680538900505 0.9996899996989428 0.0480632607295877 2 Q9NPR9 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9790035587188622 2.9000706848864133 0.0037307851788557 0.9997224297094088 0.0480632607295877 2 Q9H2D1 1 +Beta tubulin [IPR002453] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.9998455441289752 0.0480632607295877 4 P07437,Q9BVA1,P68371 3 +Tubulin [IPR000217] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.9998455441289752 0.0480632607295877 4 P07437,Q9BVA1,P68371 3 +Haem oxygenase-like [IPR016053] 0.961209964412814 2.828944238364937 0.00467018352802 0.9999648659668104 0.0480632607295877 2 P30519 1 +Haem oxygenase [IPR002051] 0.961209964412814 2.828944238364937 0.00467018352802 0.9999648659668104 0.0480632607295877 2 P30519 1 +Porin, eukaryotic type [IPR001925] 0.9555001779992918 2.8037843850621114 0.0050506668638463 0.999984797503794 0.0480632607295877 3 P45880,P21796 2 +Calcium uptake protein 1/2/3 [IPR039800] 0.952313167259789 2.7931425287881715 0.0052198686886486 0.99998952674505 0.0480632607295877 2 Q9BPX6 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9402135231316774 2.7441945211494825 0.00606595817824 0.9999983766002196 0.0480632607295877 2 Q9Y487 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9402135231316774 2.7441945211494825 0.00606595817824 0.9999983766002196 0.0480632607295877 2 Q9Y487 1 +Endoplasmic reticulum vesicle transporter [IPR045888] 0.9305785274703232 2.702333858277699 0.0068854586153468 0.9999997335866064 0.0480632607295877 3 Q9Y282 1 +Ribosomal protein S6 kinase II [IPR016239] 0.9227758007117488 2.673124551158895 0.007514834341864 0.999999933574155 0.0480632607295877 2 Q15418 1 +Eukaryotic porin/Tom40 [IPR027246] 0.9144362994496416 2.6334647491673215 0.0084518608629715 0.9999999916142064 0.0487316503967649 4 P45880,P21796 2 +Copper chaperone SCO1/SenC [IPR003782] 0.9053380782918152 2.601425551933604 0.0092837212843677 0.999999998666742 0.0497062316210973 2 O75880 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.9053380782918152 2.601425551933604 0.0092837212843677 0.999999998666742 0.0497062316210973 2 O75880 1 +Peptidase M3A/M3B [IPR045090] 0.9047712671170594 2.595924167163269 0.0094336883196908 0.9999999990431 0.0497062316210973 3 P52888 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.9000000000000061 2.5793501031370227 0.0098986408022025 0.99999999965792 0.0501611097536677 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.9000000000000061 2.5793501031370227 0.0098986408022025 0.99999999965792 0.0501611097536677 2 O96005 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.8996084015663983 2.5744691000518314 0.0100394053649566 0.9999999997494836 0.0501611097536677 3 Q9ULX6,O43823 2 +HnRNP R/Q splicing factor [IPR006535] 0.8946619217081851 2.5572149225204557 0.0105514003660358 0.9999999999193536 0.0506201317108683 2 O60506 1 +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.8843416370106835 2.5142502793184582 0.0119285747180164 0.9999999999961872 0.0514478488330197 2 P48735 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.8764684941260357 2.4776159651376184 0.0132263420134015 0.9999999999997858 0.053785278322853 3 P28072,P28074 2 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.8740213523131766 2.471060727624604 0.0134712940253902 0.9999999999998758 0.0540187184366551 2 O15254 1 +Acyl-CoA oxidase [IPR012258] 0.8740213523131766 2.471060727624604 0.0134712940253902 0.9999999999998758 0.0540187184366551 2 O15254 1 +Derlin [IPR007599] 0.8708185053380773 2.457611197735906 0.013986450374626 0.9999999999999604 0.0546244434417215 2 Q9BUN8 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8701067615658373 2.454619457232606 0.0141033797213649 0.9999999999999696 0.054788129378565 2 Q9NVI7 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.8683274021352325 2.4471354001884325 0.0143996732329987 0.9999999999999842 0.0549646063649829 2 Q96J02 1 +Major facilitator superfamily [IPR011701] 0.870095778748769 2.442214805354076 0.0145974581558763 0.9999999999999898 0.055273264992939 6 Q8NHS3,Q14728,Q96ES6,Q5SR56 4 +Amino acid/polyamine transporter I [IPR002293] 0.8640569395017904 2.4291462161830446 0.015134427405185 0.9999999999999968 0.0555677274373711 2 P30825 1 +Bcl2-like [IPR002475] 0.8508896797153094 2.373435215713086 0.0176234843670952 1.0 0.0593134473860303 2 Q07820 1 +Bcl-2 family [IPR026298] 0.8508896797153094 2.373435215713086 0.0176234843670952 1.0 0.0593134473860303 2 Q07820 1 +Aminopeptidase N-type [IPR034016] 0.8305163243109857 2.2777722011716484 0.0227401534015598 1.0 0.0659502698861141 4 Q9UIQ6,P55786 2 +Protein arginine N-methyltransferase [IPR025799] 0.8299626274656255 2.2753752069011544 0.0228834313698858 1.0 0.0659502698861141 4 Q86X55 1 +Ancient conserved domain protein family [IPR045095] 0.8103202846975106 2.1994591253592857 0.0278452924809453 1.0 0.0726103114047404 2 Q8NE01 1 +Proteasome B-type subunit [IPR023333] 0.8004648991587813 2.1374938772718273 0.032557843183733 1.0 0.0795360291248118 7 P49721,P28074,P28072 3 +TAF15/EWS/TLS family [IPR034870] 0.7913848344606749 2.111666212852884 0.034715088961174 1.0 0.0822278485556025 3 Q92804,P35637 2 +Transmembrane emp24 domain-containing protein [IPR015720] 0.7868398672645119 2.078052773310134 0.0377044987623718 1.0 0.086958480829849 6 P49755,Q15363,Q9Y3B3,Q9Y3A6 4 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.7824606009470249 2.0723878425362616 0.0382292862309481 1.0 0.0875355460667035 3 P12235 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7854626481670466 2.0719030355602435 0.0382744848323288 1.0 0.087535904245963 6 P09960,Q9NZ08,Q9UIQ6,P55786 4 +Dynamin [IPR022812] 0.760876236748181 1.976698989064151 0.0480756651574729 1.0 0.1005093343129993 3 O60313 1 +Nonaspanin (TM9SF) [IPR004240] 0.7554501661482054 1.952492382445644 0.0508797744741769 1.0 0.1043797620532973 3 Q9HD45 1 +Proteasome, subunit alpha/beta [IPR001353] 0.7219933483501126 1.7758934622584626 0.0757504787432912 1.0 0.1352327456755379 14 P49721,P60900,P28072,P28074 4 +Adenylyl-sulfate kinase [IPR002891] 0.7074733096085392 1.7430105961312403 0.081331763933369 1.0 0.1419790499167694 2 O43252 1 +Nucleosome assembly protein (NAP) [IPR002164] 0.7090690826596874 1.73658006914484 0.0824613200430417 1.0 0.1432895962802391 4 Q99733,P55209 2 +Prefoldin alpha-like [IPR004127] 0.7028469750889813 1.7219899184390708 0.0850713447785911 1.0 0.1458461004772247 2 P61758 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7020224742342613 1.7110358662180072 0.0870744920462542 1.0 0.1481212826656391 3 P51114 1 +SCAMP [IPR007273] 0.688425616919422 1.648741986216715 0.0992005045966362 1.0 0.1617174892643079 3 O15127 1 +Tumour protein D52 [IPR007327] 0.6580071174377328 1.5163849042944744 0.1294220539039576 1.0 0.193294969395754 2 O43399 1 +P-type ATPase [IPR001757] 0.6593489306613693 1.499653157996053 0.1337042701961508 1.0 0.1979365243241665 5 Q9HD20,P16615,P20020 3 +Erlin1/2 [IPR033294] 0.6309608540925231 1.390979259821456 0.1642317160873565 1.0 0.227135282263723 2 O75477 1 +Prefoldin beta-like [IPR002777] 0.6301543298450961 1.3785909677352437 0.1680209029556441 1.0 0.230660274671564 3 O15212 1 +Tropomyosin [IPR000533] 0.6264878747249787 1.3614546698385723 0.1733700494424321 1.0 0.2348048596067045 3 P09493 1 +Annexin [IPR001464] 0.6161361271243933 1.2831073210839974 0.1994544792212313 1.0 0.258124491419798 7 P12429,P04083,P50995 3 +Ribosomal RNA adenine dimethylase [IPR011530] 0.5918149466192159 1.2083001048839015 0.2269318481464353 1.0 0.2817040675857449 2 Q9UNQ2 1 +Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737] 0.5918149466192159 1.2083001048839015 0.2269318481464353 1.0 0.2817040675857449 2 Q9UNQ2 1 +Mitochondrial carrier protein [IPR002067] 0.5901994325882511 1.1436277913597093 0.2527780310481762 1.0 0.3039718254810944 10 P12235,Q9HC21,P53007,Q9UJS0,P12236 5 +Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515] 0.557295373665478 1.0469775189862296 0.2951099468432363 1.0 0.3397137787957797 2 Q13310 1 +Mitochondrial Rho GTPase [IPR021181] 0.5473309608540867 1.0005475411126368 0.3170456025665835 1.0 0.3558588145054951 2 Q8IXI1 1 +Glutathione Transferase family [IPR040079] 0.5529937407756168 0.9636548242970756 0.3352190104869859 1.0 0.3701939778109808 10 Q8TB36,Q9H7Z7,Q13505 3 +Dynein family light intermediate chain [IPR022780] 0.5330960854092514 0.9344499722459724 0.3500718305739116 1.0 0.3825473220884989 2 Q9Y6G9 1 +Dynein 1 light intermediate chain [IPR008467] 0.5330960854092514 0.9344499722459724 0.3500718305739116 1.0 0.3825473220884989 2 Q9Y6G9 1 +Microtubule-associated protein RP/EB [IPR027328] 0.5266903914590771 0.9048238348044066 0.3655587224581165 1.0 0.3943570462362054 2 Q15555 1 +HnRNP-L/PTB [IPR006536] 0.5185053380782945 0.8671017700696871 0.3858862508486311 1.0 0.4094318525953273 2 P14866 1 +Isoleucine-tRNA ligase [IPR002301] 0.5177935943060408 0.8638294915152614 0.3876815644307276 1.0 0.410343143800833 2 Q9NSE4 1 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.5099644128113839 0.8279278388180145 0.4077113679526714 1.0 0.4276187683984217 2 Q14739 1 +Intracellular chloride channel [IPR002946] 0.4953736654804261 0.7615496369350376 0.4463288430493275 1.0 0.4621486271838736 2 O00299 1 +ClpA/B family [IPR001270] 0.495017793594306 0.7599404863425449 0.4472901596596625 1.0 0.4629252431810678 2 Q15645 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.4889679715302372 0.7326652695375087 0.4637626115326978 1.0 0.4797468752918513 2 Q9Y3C6 1 +Monothiol glutaredoxin-related [IPR004480] 0.4879003558718858 0.7278683870683094 0.4666941565712506 1.0 0.4825516267331807 2 Q86SX6 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.4832740213523034 0.7071422786915822 0.4794780645583558 1.0 0.4939052371637788 2 P42285 1 +14-3-3 protein [IPR000308] 0.4878831076265084 0.6864183575243016 0.4924493315457794 1.0 0.5063146341702499 6 Q04917,P61981,P31946,P63104,P62258 5 +DNA-directed RNA polymerase, subunit 2 [IPR015712] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5069668061905992 3 P30876,Q9NW08 2 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.4772241992882563 0.6801960048015301 0.4963803617182085 1.0 0.5091616912568329 2 Q13868 1 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.4661921708185098 0.6315680448256944 0.5276691728768621 1.0 0.5408017696846904 2 Q9H9Q2 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.4612099644128135 0.6098457646725041 0.5419639823813571 1.0 0.554361851259362 2 Q9H267 1 +U3 snoRNP protein/Ribosome production factor 1 [IPR044281] 0.4597864768683286 0.6036688570016988 0.5460638233921125 1.0 0.5580344389235627 2 Q96G21 1 +Palmitoyl protein thioesterase [IPR002472] 0.4590747330960716 0.6005854654673666 0.5481161210502687 1.0 0.5596097023397665 2 P50897 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4548042704626318 0.5821579485195358 0.5604602953172739 1.0 0.5716799381006272 2 O60884 1 +Isocitrate dehydrogenase NAD-dependent [IPR004434] 0.4530249110320291 0.5745177270149917 0.5656175082118804 1.0 0.576671922053155 2 O43837 1 +Actin family [IPR004000] 0.457784111150684 0.5628708875410325 0.5735228054332666 1.0 0.5844597519554824 5 P61163,O96019,Q9NZ32,P61160 4 +DNA2/NAM7-like helicase [IPR045055] 0.4519230769230978 0.5480546641696566 0.5836543687243045 1.0 0.5942317480831557 4 P42694,O60306,Q9HCE1 3 +Oxysterol-binding protein [IPR000648] 0.4435747931316665 0.5020941899767134 0.6156012669170752 1.0 0.6258850931857595 5 Q9BZF3 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.4382342470630162 0.5009113176672625 0.616433537009047 1.0 0.6264405749475056 3 P04899,Q14344 2 +Protein PRRC2 [IPR033184] 0.4352313167259807 0.4994677981231042 0.6174498669533777 1.0 0.6271825027792538 2 Q9Y520 1 +Gamma-tubulin complex component protein [IPR007259] 0.4295373665480439 0.476024512947478 0.6340569143459334 1.0 0.6437528727210102 2 Q9BSJ2 1 +KH domain-containing BBP-like [IPR045071] 0.4339048056034624 0.4722141851779071 0.636773915659802 1.0 0.6462119727700909 4 O75525 1 +Ribonuclease CAF1 [IPR006941] 0.4220640569395043 0.4457268407688264 0.6557945737527253 1.0 0.6648986168867289 2 Q9UIV1 1 +Sec1-like protein [IPR001619] 0.4127492877492906 0.387176709287687 0.6986253914119827 1.0 0.7066889347108283 4 O00186,Q9H267,Q96AX1 3 +Prohibitin [IPR000163] 0.402846975088962 0.370566008251056 0.710960803733083 1.0 0.7188348504749353 2 Q99623 1 +Importin beta family [IPR040122] 0.4060030803965705 0.3611217526617741 0.718008432664335 1.0 0.7256256807968441 4 Q8TEX9 1 +Protein disulphide isomerase [IPR005792] 0.3844784620861565 0.2923520071051541 0.7700174987983697 1.0 0.7763959226264279 3 P07237,P13667 2 +Mini-chromosome maintenance protein [IPR031327] 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.8519712722369658 6 Q14566 1 +E3 ubiquitin ligase RBR family [IPR031127] 0.3387076762528525 0.1474420671700871 0.8827831035331037 1.0 0.8848022780608555 3 O95376 1 +Sirtuin family [IPR003000] 0.3227758007117477 0.1151399233203666 0.9083342160816752 1.0 0.9095796469081124 2 Q8IXJ6 1 +La domain containing protein [IPR045180] 0.3327161050928851 0.1128395820067315 0.9101577368255158 1.0 0.9109893108198744 5 Q71RC2 1 +Succinate--CoA synthetase, beta subunit [IPR005809] 0.3156583629893312 0.0980018935642423 0.9219307897609116 1.0 0.9223517627242728 2 Q96I99 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d5534b0a68b630b59915b2fc77abb6584dd0462f --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "16S/18S rRNA aminocarboxypropyltransferase Tsr3 [IPR022968]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5-formyltetrahydrofolate cyclo-ligase [IPR002698]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Acetoacetyl-CoA synthase [IPR005914]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA-binding domain-containing protein 5 [IPR016347]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat-containing protein 6 [IPR040104]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BBP/SF1 family [IPR031150]", "BCP1 family [IPR025602]", "BRCA1-A complex subunit BRE [IPR010358]", "BRI3-binding protein [IPR033367]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beta tubulin [IPR002453]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicaudal-D protein [IPR018477]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD34/Podocalyxin [IPR013836]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COG complex component, COG2 [IPR009316]", "COMM domain-containing protein 4 [IPR037356]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cation/H+ exchanger, CPA1 family [IPR018422]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell cycle regulator Mat89Bb [IPR019355]", "Cell division cycle protein 123 [IPR009772]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein I [IPR012485]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Complex I intermediate-associated protein 30, mitochondrial [IPR039131]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1C [IPR027333]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XPF [IPR006167]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dim1 family [IPR004123]", "Dimethylarginine dimethylaminohydrolase [IPR033199]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphthine synthase [IPR004551]", "Divalent ion tolerance protein, CutA [IPR004323]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein light chain Tctex-1 like [IPR005334]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Erg28 [IPR005352]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Sec10-like [IPR009976]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM98 [IPR018797]", "FMP27 [IPR045167]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gasdermin-E [IPR042377]", "Gem-associated protein 4 [IPR033265]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HEXIM [IPR024872]", "HIRA-interacting protein 3 [IPR037647]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IQ motif and SEC7 domain-containing protein 1 [IPR030737]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon gamma receptor alpha subunit [IPR008355]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intracellular chloride channel [IPR002946]", "Intraflagellar transport protein 25 [IPR033558]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intron Large complex component GCFC2-like [IPR012890]", "Iron regulatory protein 1 [IPR029784]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Kae1/TsaD family [IPR017861]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Spc25 [IPR045143]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "MDN2-binding protein [IPR039061]", "METTL16/RlmF family [IPR010286]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MKRN-like [IPR045072]", "MOB kinase activator family [IPR005301]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter protein 1 [IPR006844]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonic aciduria and homocystinuria type D protein [IPR019362]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthiotransferase [IPR005839]", "Methyltransferase METTL16/PsiM [IPR017182]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microtubule associated protein 1 [IPR026074]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial outer membrane transport complex protein, metaxin [IPR017410]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 [IPR033202]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Na+/H+ exchanger [IPR004709]", "Na+/H+ exchanger, isoform 6/7/9 [IPR002090]", "Nck-associated protein 1 [IPR019137]", "Negative cofactor 2 complex subunit beta [IPR042225]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Neurochondrin [IPR008709]", "Neurofilament medium polypeptide [IPR027697]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nicotinate-nucleotide pyrophosphorylase [IPR004393]", "Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD [IPR027277]", "Nitric oxide synthase-interacting protein [IPR016818]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC family [IPR037898]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ORC ubiquitin ligase 1 [IPR039209]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIB [IPR006408]", "P-type ATPase, subfamily IV [IPR006539]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PH-interacting protein [IPR028738]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic antigen Ma [IPR026523]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Partner of Y14 and mago [IPR039333]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, chymotrypsin family [IPR001314]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phospholipid-transporting ATPase IG [IPR030363]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Podocalyxin [IPR017403]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable E3 ubiquitin-protein ligase makorin-2 [IPR026293]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM8A1 [IPR039871]", "Protein FRG1 [IPR010414]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein NDRG3 [IPR030692]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A11 [IPR028482]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein TFG [IPR033512]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "RAD3/XPD family [IPR001945]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase, Rpb8 [IPR005570]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab21 [IPR041833]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rad21/Rec8-like protein [IPR039781]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulon-4-interacting protein 1 [IPR037397]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleases P/MRP protein subunit Rpp20/Pop7 [IPR014612]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L51, mitochondrial [IPR019373]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S26e [IPR000892]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small acidic protein [IPR026714]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of hairless-like [IPR040159]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetracycline resistance protein TetA/multidrug resistance protein MdtG [IPR001958]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 21A/21B [IPR040364]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor TFIID subunit 2 [IPR037813]", "Transcription initiation factor TFIID subunit 5 [IPR037783]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transgelin-2 [IPR001061]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin polyglutamylase TTLL4 [IPR027748]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Type-1 angiotensin II receptor-associated protein [IPR009436]", "Tyrosine-protein kinase, insulin-like receptor [IPR016246]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "UAA transporter [IPR013657]", "UAP56-interacting factor [IPR009782]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier 1 [IPR005375]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YEATS [IPR005033]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 638 [IPR033096]", "Zinc transporter Msc2-like [IPR045316]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea and eukaryote [IPR034680]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-specific 2-thiouridylase [IPR004506]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AACS", "AAR2", "AARS", "AARS2", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABHD12", "ABRAXAS2", "ACAA2", "ACADM", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGL", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APLP2", "APOL2", "APOOL", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC6", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "B3GALT6", "B4GAT1", "BABAM2", "BAIAP2", "BANF1", "BASP1", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUD31", "BYSL", "C11orf58", "C12orf43", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CAST", "CBFB", "CBR1", "CBX3", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC37", "CDC42", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK5RAP3", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CENPF", "CENPI", "CEP170", "CEP44", "CEP55", "CEPT1", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHERP", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CIAPIN1", "CIP2A", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG7", "COIL", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF7", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX54", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAH", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM213A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNTB", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALK1", "GALM", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GCAT", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMFB", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOLIM4", "GOLM1", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPS1", "GPX8", "GRPEL1", "GRSF1", "GSDME", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS5", "HCFC1", "HDAC1", "HDAC2", "HDHD2", "HDHD5", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB3", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO4", "IPO5", "IQSEC1", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KHDRBS3", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1147", "KIAA2013", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG3", "LIMA1", "LLGL1", "LMAN1", "LNPEP", "LONP1", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANF", "MAP1B", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MAU2", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKRN2", "MLEC", "MMADHC", "MMS19", "MOB4", "MOGS", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MTX3", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "NAA15", "NAA25", "NAA35", "NAA40", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NAT10", "NAXE", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCLN", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF1", "NDUFB10", "NDUFB4", "NDUFB5", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NEDD4L", "NEFM", "NELFB", "NELFCD", "NELFE", "NF1", "NHP2", "NIP7", "NIPBL", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NSA2", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PAWR", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDXDC1", "PEBP1", "PECR", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITPNB", "PKM", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POLA1", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PTBP1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM39", "RBM45", "RBM5", "RBM8A", "RBPJ", "RCC2", "RCL1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "ROCK1", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTFDC1", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARS", "SARS2", "SART1", "SBDS", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3BGRL", "SH3GL1", "SH3GLB1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMPD4", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1L", "SPR", "SPTBN1", "SQLE", "SRFBP1", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TARS", "TARS2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TECR", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TK1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMX2", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL5", "UBR1", "UBR4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WBP11", "WBP2", "WDR11", "WDR12", "WDR18", "WDR33", "WDR46", "WDR82", "WFS1", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YEATS2", "YIF1A", "YIPF5", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7A", "ZCCHC3", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10"], "leading_proteins": ["ACOX3", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "AKAP8", "AKAP8L", "ANXA1", "ANXA11", "ANXA3", "AQR", "ARIH2", "ATAD3A", "ATP13A1", "ATP2A2", "ATP2B1", "ATP6V0A2", "CARM1", "CLIC1", "CLPTM1", "CNNM3", "CNOT7", "COPS7B", "DERL1", "DIMT1", "DNAJA2", "DYNC1LI1", "ERAP1", "ERGIC3", "ERLIN1", "EXOSC2", "FUS", "FXR1", "GDAP1", "GLRX5", "GNA13", "GNAI2", "GPR108", "HELZ", "HMOX2", "HNRNPL", "IARS2", "IDH2", "IDH3B", "IMP4", "IPO4", "ITCH", "KHDRBS3", "LARP4", "LBR", "LNPEP", "LTA4H", "MAPRE2", "MCL1", "MCM6", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MICU1", "MOV10", "MTX1", "NAP1L1", "NAP1L4", "NPEPPS", "OPA1", "OSBPL6", "P4HB", "PABPC4", "PAPSS1", "PDIA4", "PFDN6", "PHB2", "POLR2B", "POLR3B", "PPIL1", "PPT1", "PRRC2C", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PTGES2", "RHOT2", "RPS6KA1", "SCAMP2", "SCO1", "SIRT2", "SKIV2L2", "SLC25A1", "SLC25A13", "SLC25A19", "SLC25A32", "SLC25A4", "SLC25A6", "SLC7A1", "STXBP3", "SUCLG2", "SYNCRIP", "TAF15", "THOP1", "TIMM17A", "TM9SF3", "TMED10", "TMED2", "TMED5", "TMED7", "TPD52L2", "TPM1", "TRIP13", "TUBB", "TUBB2B", "TUBB4B", "TUBGCP2", "VBP1", "VDAC1", "VDAC2", "VPS33A", "VPS33B", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a5d23ef0d4602d3777a6897315361ae03a307f5d --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/plot_0.png b/interpro_homologous_superfamily/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1c6a894ebc86b53d7804dd6b96855c8ec9770a4c --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a10492774f02481a3ebd1a513f5f53726142ea9dd9dfd68f66c1520b55d33aa8 +size 196643 diff --git a/interpro_homologous_superfamily/basic/idx2term.json b/interpro_homologous_superfamily/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cbcf1ac92cb5da54006d796b7a66086a839a9f6d --- /dev/null +++ b/interpro_homologous_superfamily/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Nucleophile aminohydrolases, N-terminal [IPR029055]", "2": "Chaperone J-domain superfamily [IPR036869]", "3": "Tetratricopeptide-like helical domain superfamily [IPR011990]", "4": "14-3-3 domain superfamily [IPR036815]", "5": "C2 domain superfamily [IPR035892]", "6": "EF-hand domain pair [IPR011992]", "7": "HAD-like superfamily [IPR036412]", "8": "HAD superfamily [IPR023214]", "9": "Band 7/SPFH domain superfamily [IPR036013]", "10": "K Homology domain, type 1 superfamily [IPR036612]", "11": "HotDog domain superfamily [IPR029069]", "12": "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "13": "Immunoglobulin-like fold [IPR013783]", "14": "Thioredoxin-like superfamily [IPR036249]", "15": "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "16": "RNA-binding domain superfamily [IPR035979]", "17": "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/basic/plot_0.png b/interpro_homologous_superfamily/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..bd10f3d980520a8075f69a06f1b46f7f472f49ad --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1d64dfff025ce0ad071ef5e0317c29ef274c9b0ee3a0b7b46cd453456117284 +size 142012 diff --git a/interpro_homologous_superfamily/basic/plot_1.png b/interpro_homologous_superfamily/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..21abdda77636eb51db2a1b7ad3b97352a63cac29 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24aa47d8fe54ddf0690dffceb6f704fb3c1ee5a139ec691bb343928a5fbfeb88 +size 139687 diff --git a/interpro_homologous_superfamily/basic/plot_10.png b/interpro_homologous_superfamily/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..8b94e535bb0c05e55297ca59a14f2509ff40c59a --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d426be43c3ab45f4731ce1719f3742b025b78b79d061de519b4e7baf14ec8ea +size 154672 diff --git a/interpro_homologous_superfamily/basic/plot_11.png b/interpro_homologous_superfamily/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..30926c93a119a77e79a221c0f694f083542972a2 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8656317b22759c19043b23b43f7ffa126c0ad984ecd385a4ae342c203011fef +size 137470 diff --git a/interpro_homologous_superfamily/basic/plot_12.png b/interpro_homologous_superfamily/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..43cfb0f187f3d59d18043d7ce05fce13f5658070 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d1af3aec2cea8e6e794e7c98128125c9b04657eabbd18d13a379f3560cf58b1 +size 149504 diff --git a/interpro_homologous_superfamily/basic/plot_13.png b/interpro_homologous_superfamily/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..5fa85b8c30bca10083cb480d799af309f0614730 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:40ada65b711179a2a313db049e108eecc22258a3c4b1b264c56122044460de60 +size 144775 diff --git a/interpro_homologous_superfamily/basic/plot_14.png b/interpro_homologous_superfamily/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..de8629ce9af8547e6912bd89f0ff9a23bb337055 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d77f4266c5919f5303a88cb2c58876400acf42c68051137ff1d1939c31f5081 +size 150583 diff --git a/interpro_homologous_superfamily/basic/plot_15.png b/interpro_homologous_superfamily/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..2695dc65051e7600f4ea0120a1c53c1a25ac4c0c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f44cb309ecec7d5b3c4d4adb4338278107a22353ccefb21955bc0f4778d1e948 +size 156302 diff --git a/interpro_homologous_superfamily/basic/plot_16.png b/interpro_homologous_superfamily/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..d3a0321dcb20bee23eb8fadbdd100b0a33a6dcf6 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a508eb5b913d1280b654b8b9a968def56b1ef762782d74e58f0b676de518b6a3 +size 152592 diff --git a/interpro_homologous_superfamily/basic/plot_17.png b/interpro_homologous_superfamily/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..198682d378e4ab2ba6d13f0055b77fb0fd3d9720 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e1b7d2ed3e67dd87c98d536745d912a95e958763ef55ef91867b231f4d59a83 +size 151248 diff --git a/interpro_homologous_superfamily/basic/plot_2.png b/interpro_homologous_superfamily/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..b2dae455b14ad2ee203387613f49e2a952c32fe2 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bbf290badd542b2095eed96ee075ed3b76606c8d83cbdee78cee10024badcc28 +size 141508 diff --git a/interpro_homologous_superfamily/basic/plot_3.png b/interpro_homologous_superfamily/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..32d0e3c6277014763e31bca9653da2414bfc7f4d --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ee32bc722a5ad3630675ffc48dbd440f3c5db116677e6d9f0ebbdb833ae5e86 +size 149853 diff --git a/interpro_homologous_superfamily/basic/plot_4.png b/interpro_homologous_superfamily/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..d43ad2a78a613cdb6b631f55717f4d1041525fd8 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:937072b6587cf479f98c1ab783efbe558118c645d48c3e2f14e73e6936de6662 +size 133841 diff --git a/interpro_homologous_superfamily/basic/plot_5.png b/interpro_homologous_superfamily/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..8b37c9fe55427bb2cf53bd817d947556d1151eea --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:96fd9bed8fa2cfdcb2c4309d3c73cb41aeb7f4dcfb5a514a0c5563f533de412a +size 139011 diff --git a/interpro_homologous_superfamily/basic/plot_6.png b/interpro_homologous_superfamily/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..01e06b43c9ebb9fb81a6c8492b6131b15005f406 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bf01796811a66b0ff84839c753cf58374fca98fd5662fb1e41fa76cd7249d81f +size 140735 diff --git a/interpro_homologous_superfamily/basic/plot_7.png b/interpro_homologous_superfamily/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..3dbd5857f1ae2dcc6b22dff151028a9d27664994 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7bf39ce8e8089d58d7f630b6f86b4329f163524bdc2f0bfc141c14e60580e3b7 +size 139134 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..75736ec65d9d4bca9faba40093a596c725327078 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1d4cfd6d531b42e57f779f35126796c16c9a003cbd059fda01b9353d928cee9 +size 137813 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..93e08f933de488da64f52474c73cf0ab04c79cf5 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f6170041d8c02b78889bf64ab769fdd1b5df1122da914b229ebf097c6714c0f +size 130365 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..64db8e1f3a882aa8ea6dc68604716e940d45a396 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e11d556f40fc0ebcced0daf584528ef616b09dd1d975283106f152d1fd431bc0 +size 197706 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..30424f850050b99d89e350954e0ca095cc7bc455 --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 4 5 2.8153220606250997 0.0048728373467756 3.7524271844660193 6.847087378640777 0.510735400099038 0.3891602594566672 2.000453572849188 1.1755668998633355 1.2190917823770269 0.3170422836523225 3.7847211828509623e-06 1.0 2.674004210290638e-05 6.786735540833244e-05 0.0017429018144962 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 4 5 2.6094504570171084 0.0090687776771443 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 1.3401087212461636e-05 0.0550816697898294 0.0001725606130307 0.0001383364889708 0.0001575214550341 +Mitochondrial carrier domain superfamily [IPR023395] 10 19 2.133132555493161 0.0329138538362077 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0001334964242414 0.0136970422924113 0.00553293278753 2.8354518268714176e-05 1.1521546305420906e-06 +GOLD domain superfamily [IPR036598] 3 5 1.9752615573292225 0.0482384734127181 1.6893203883495145 3.9635922330097086 0.2675315261133384 0.342496534532029 0.9581447102086512 0.7543625282431146 1.3547328505855056 0.3000927322795711 1.0 1.0 1.0 1.0 0.0009118158302113 +Histidine phosphatase superfamily [IPR029033] 0 5 1.9723467056002533 0.0485700412846341 1.1262135922330097 5.514563106796117 0.7684120115144248 0.3501978831807532 1.087703661549979 0.6771453167512235 0.986671075305162 0.2738673806375665 0.2028965966813109 0.0771453392642774 0.1500965904253892 0.3388735835116871 0.5711774547855736 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5612c581bafbc412fa99afbe23778c52dc9631d5 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 917, + "title": "Average number of proteins per term", + "value": 4.608505997818975 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a649f2364e3c09ee279d52f18c4bf18e9e886927 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6fe81760a19bd6ca5cf27e185c52d721e04f1b71 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,117 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.974596183040014 0.0786631747582242 4 P07437,Q9BVA1,P68371 3 +Tubulin, C-terminal [IPR023123] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.974596183040014 0.0786631747582242 4 P07437,Q9BVA1,P68371 3 +Tubulin/FtsZ, C-terminal [IPR008280] 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.974596183040014 0.0786631747582242 4 P07437,Q9BVA1,P68371 3 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.964768683274024 2.843220239207112 0.0044660197779802 0.9835019385127391 0.0786631747582242 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.964768683274024 2.843220239207112 0.0044660197779802 0.9835019385127391 0.0786631747582242 2 Q15392 1 +Haem oxygenase-like, multi-helical [IPR016084] 0.961209964412814 2.828944238364937 0.00467018352802 0.9863305205176022 0.0786631747582242 2 P30519 1 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.9590309939437116 2.8153220606250993 0.0048728373467756 0.9886588119145356 0.0786631747582242 5 P07437,Q9BVA1,Q9BUF5,P68371 4 +Porin domain superfamily [IPR023614] 0.9144362994496416 2.6334647491673215 0.0084518608629715 0.99958336274313 0.0786631747582242 4 P45880,P21796 2 +Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080] 0.9124555160142432 2.63076686158181 0.0085192455642912 0.9996085352943548 0.0786631747582242 2 P52888 1 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.9091556822230116 2.6094504570171084 0.0090687776771443 0.9997645488181324 0.0786631747582242 5 O43169,O00264,O15173,Q8WUJ1 4 +GMP phosphodiesterase, delta subunit superfamily [IPR037036] 0.9049483802064882 2.596659192991696 0.0094135273372968 0.9998288706934368 0.0786631747582242 3 Q13432,A6NIH7 2 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.9047712671170594 2.595924167163269 0.0094336883196908 0.9998320349451147 0.0786631747582242 3 P52888 1 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.8790035587188662 2.491938996797378 0.0127047856043738 0.9999919103773502 0.0843914920788848 2 P49356 1 +Ribokinase-like [IPR029056] 0.8779359430605084 2.4874695077353035 0.0128655482007074 0.9999930325201032 0.0843914920788848 2 Q9BRR6 1 +Bcl-2-like superfamily [IPR036834] 0.8508896797153094 2.373435215713086 0.0176234843670952 0.9999999170339984 0.0914643320418998 2 Q07820 1 +L27 domain superfamily [IPR036892] 0.8283475783475766 2.2683797711751628 0.0233060696342155 0.9999999995939924 0.1008328509084047 4 O14936,Q14168,Q9NZW5 3 +Restriction endonuclease type II-like [IPR011335] 0.8195729537366649 2.239447077534154 0.025126841128928 0.9999999999266468 0.1043465278699563 2 Q9BQP7 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8205455668156689 2.234507041152111 0.0254497297740168 0.9999999999458632 0.1043465278699563 4 P52888 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.7923985085228474 2.133132555493161 0.0329138538362077 0.999999999999953 0.1122805260079961 19 Q70HW3,Q9NZJ7,O43772,Q9HC21,Q9UJS0,Q00325,Q9Y619,Q9Y6C9,Q9H2D1,Q9UBX3 10 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.7759971509971415 2.0386036687360183 0.0414895987924042 1.0 0.1307878580526759 4 P01889,P04439,P10321 3 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.7759971509971415 2.0386036687360183 0.0414895987924042 1.0 0.1307878580526759 4 P01889,P04439,P10321 3 +Isoprenoid synthase domain superfamily [IPR008949] 0.7697508896797178 2.021987504743684 0.0431776427458081 1.0 0.1339153643338493 2 P37268 1 +GOLD domain superfamily [IPR036598] 0.7629234766834188 1.9752615573292225 0.0482384734127181 1.0 0.1386667088384405 5 Q15363,O76054,Q9Y3B3 3 +PITH domain superfamily [IPR037047] 0.7551601423487577 1.9573203802565473 0.0503098128476318 1.0 0.1405934092806056 2 O43396 1 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.7398153215461272 1.8824090026438849 0.0597805045153903 1.0 0.1526432970594349 3 O43813 1 +NAP-like superfamily [IPR037231] 0.7090690826596874 1.73658006914484 0.0824613200430417 1.0 0.1904711095200737 4 Q99733,P55209 2 +Protein-tyrosine phosphatase-like [IPR029021] 0.7043688228393881 1.699458613903453 0.0892328061139164 1.0 0.1981285932856966 7 O14976,Q9Y217,Q06124 3 +LEM/LEM-like domain superfamily [IPR011015] 0.6981294390557212 1.674013186240746 0.0941280078611652 1.0 0.2027984918576273 6 Q86XL3,P50402,P42167 3 +DNA-directed RNA polymerase, insert domain superfamily [IPR036643] 0.6889679715302486 1.658700992761141 0.0971760592580728 1.0 0.2070122009131826 2 O15160 1 +RNA polymerase, RBP11-like subunit [IPR036603] 0.6889679715302486 1.658700992761141 0.0971760592580728 1.0 0.2070122009131826 2 O15160 1 +Sec7 domain superfamily [IPR035999] 0.6701067615658353 1.5721774958542245 0.1159093929667776 1.0 0.2265603433652613 2 Q6DN90 1 +Sec7, C-terminal domain superfamily [IPR023394] 0.6701067615658353 1.5721774958542245 0.1159093929667776 1.0 0.2265603433652613 2 Q6DN90 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.6769716436484151 1.5713377983479269 0.1161042058170211 1.0 0.2265603433652613 7 P09960,Q9NZ08,Q9UIQ6,P55786 4 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.6769716436484151 1.5713377983479269 0.1161042058170211 1.0 0.2265603433652613 7 P09960,Q9NZ08,Q9UIQ6,P55786 4 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.6711257280068638 1.5316208519057677 0.1256160238572956 1.0 0.2401582718592929 17 P49721,P60900,P28074,Q06203,P28072 5 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.6593489306613693 1.499653157996053 0.1337042701961508 1.0 0.2480124187697648 5 Q9HD20,P16615,P20020 3 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.6593489306613693 1.499653157996053 0.1337042701961508 1.0 0.2480124187697648 5 Q9HD20,P16615,P20020 3 +P-type ATPase, A domain superfamily [IPR008250] 0.6593489306613693 1.499653157996053 0.1337042701961508 1.0 0.2480124187697648 5 Q9HD20,P16615,P20020 3 +CAP Gly-rich domain superfamily [IPR036859] 0.6550373798504916 1.4945111552000412 0.1350420684595676 1.0 0.249554400773907 3 Q99426,Q15813 2 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.6565183678245435 1.4936976034233036 0.1352546752286061 1.0 0.249554400773907 4 O75027,P33527 2 +Prefoldin [IPR009053] 0.6502465995052078 1.4570104297706048 0.1451135012254309 1.0 0.2609197659288631 5 P61758,O15212,Q99471 3 +Six-hairpin glycosidase superfamily [IPR008928] 0.627758007117434 1.3760746777173185 0.168798514354731 1.0 0.281433159387797 2 P35573 1 +AF1104-like superfamily [IPR036075] 0.622775800711755 1.3528708873543316 0.1760968814362002 1.0 0.2883586433517779 2 Q9NVE7 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.6311673185329723 1.3420474658581636 0.1795806058498339 1.0 0.2924173449294873 10 P35613,P01889,P04439,P10321 4 +Annexin superfamily [IPR037104] 0.6161361271243933 1.2831073210839974 0.1994544792212313 1.0 0.3137217108848528 7 P12429,P04083,P50995 3 +K homology domain-like, alpha/beta [IPR015946] 0.5989323843416315 1.241574944521311 0.2143934309270343 1.0 0.3271194278870058 2 O75616 1 +K homology domain superfamily, prokaryotic type [IPR009019] 0.5989323843416315 1.241574944521311 0.2143934309270343 1.0 0.3271194278870058 2 O75616 1 +Rab-GTPase-TBC domain superfamily [IPR035969] 0.6015167576229822 1.2193095360792905 0.2227267305727001 1.0 0.3337261632927549 6 Q66K14 1 +Acyl-CoA N-acyltransferase [IPR016181] 0.6001564931708332 1.2013821632172472 0.2296029918849629 1.0 0.3423511277374162 8 O60502 1 +Ricin B-like lectins [IPR035992] 0.5790064061809759 1.138822531832129 0.2547771819803508 1.0 0.3667671520816039 3 Q10472 1 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.5857906066030293 1.1271093170829636 0.2596962645612386 1.0 0.3715155610025832 9 O15254,Q709F0,Q92947 3 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.5857906066030293 1.1271093170829636 0.2596962645612386 1.0 0.3715155610025832 9 O15254,Q709F0,Q92947 3 +Exoribonuclease, PH domain 2 superfamily [IPR036345] 0.5765802134903752 1.100853301914188 0.2709605090097038 1.0 0.3816755557018408 6 Q96B26,Q9NQT4 2 +PNPase/RNase PH domain superfamily [IPR027408] 0.5765802134903752 1.100853301914188 0.2709605090097038 1.0 0.3816755557018408 6 Q96B26,Q9NQT4 2 +PX domain superfamily [IPR036871] 0.5600589610921787 1.0091840432735804 0.3128863777869028 1.0 0.4140213685867098 8 Q96L92 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.5625480196574913 0.9841320541782508 0.3250505882135073 1.0 0.4252088293748733 18 Q96CU9,O95831,Q9UHG3,Q8NB78 4 +SCP2 sterol-binding domain superfamily [IPR036527] 0.5339978640085463 0.928331221457414 0.3532357835096231 1.0 0.4489647083744853 3 P51659,Q6YN16 2 +Homeobox-like domain superfamily [IPR009057] 0.549196889780339 0.9208930753437377 0.3571062542574883 1.0 0.4523017060139734 16 Q96G23,Q99543,Q8NB78 3 +MFS transporter superfamily [IPR036259] 0.5409025481314187 0.917879856279578 0.3586817686476613 1.0 0.453670595655042 8 Q8NHS3,Q14728,Q96ES6,Q5SR56 4 +EB1, C-terminal domain superfamily [IPR036133] 0.5266903914590771 0.9048238348044066 0.3655587224581165 1.0 0.4583586920909371 2 Q15555 1 +NTF2-like domain superfamily [IPR032710] 0.5258212450679182 0.8536752103792125 0.3932849732071886 1.0 0.4827875775515287 7 Q13555,Q9UBU9,O43615 3 +Chaperone J-domain superfamily [IPR036869] 0.5352614609881722 0.849020538049726 0.3958698641396823 1.0 0.4853110500215088 17 Q13217,Q9UBS4,Q9UGP8,Q99543,Q8IXB1,Q96KC8,O14976 7 +MoaB/Mog-like domain superfamily [IPR036425] 0.512455516014225 0.8393317747134904 0.4012831573109654 1.0 0.4899237547989967 2 Q9NQX3 1 +Rhomboid-like superfamily [IPR035952] 0.5145679773639222 0.8384651100263404 0.4017695350150987 1.0 0.4899237547989967 3 Q9BUN8 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3569498740368713 0.7697731067948484 0.44143449511103 1.0 0.5277645789006709 78 O76024,Q96DB5,Q96BR5,O00231,O43765,Q9UJX3,O75718,Q7Z4L5,Q6PGP7,Q9Y262,Q9Y6X3,Q9H7B4,O75153,P13674,Q13451,Q92791,Q9UJX4,Q13217,Q8IWR0,Q32P28,Q6DKK2 21 +START-like domain superfamily [IPR023393] 0.4878917378917461 0.7065103673149222 0.4798708078007414 1.0 0.5685291095003616 4 Q14849,Q9NQZ5,P48739 3 +RNA polymerase Rpb2, domain 2 superfamily [IPR037034] 0.4804270462633448 0.6944386741338588 0.4874071472731018 1.0 0.5752282548898769 2 P30876 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.4931291012451886 0.6868805674901803 0.4921579935298303 1.0 0.5789436372147175 9 Q92804 1 +14-3-3 domain superfamily [IPR036815] 0.4878831076265084 0.6864183575243016 0.4924493315457794 1.0 0.5789436372147175 6 Q04917,P61981,P31946,P63104,P62258 5 +RNA polymerase Rpb2, OB-fold [IPR014724] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5790207730559259 3 P30876,Q9NW08 2 +DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033] 0.4805980776076918 0.684312584379046 0.4937778021043992 1.0 0.5790207730559259 3 P30876,Q9NW08 2 +Immunoglobulin E-set [IPR014756] 0.4974494991753585 0.6765573092872444 0.4986868730739524 1.0 0.5825425001386171 14 Q13432,A6NIH7,O43924 3 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.4766468301581773 0.635867356900496 0.5248628805608786 1.0 0.6100117382437588 6 Q9Y3Z3 1 +Cyclic nucleotide-binding-like [IPR018490] 0.4693732193732339 0.6239227072532412 0.532678346907868 1.0 0.6175297649993867 4 Q9Y4G8,P13861,Q6P4Q7 3 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.4612099644128135 0.6098457646725041 0.5419639823813571 1.0 0.6275012270753845 2 Q9H267 1 +C2 domain superfamily [IPR035892] 0.4829423259531911 0.6032801746745785 0.546322319404513 1.0 0.6307921600664159 15 Q9UGP8,Q96PU5,P05771,Q99829,Q96J02,O14976 6 +Pyridoxal phosphate-dependent transferase, small domain [IPR015422] 0.4777844453765724 0.6027125326942582 0.5466999427435244 1.0 0.6307921600664159 11 O15269 1 +HSP20-like chaperone [IPR008978] 0.4710466190288036 0.5865395689645662 0.5575129790828628 1.0 0.6414547074265812 9 P04792 1 +Pyridoxal phosphate-dependent transferase [IPR015424] 0.4744588742793735 0.5810638817403863 0.5611974000643951 1.0 0.644077616844869 12 O15269 1 +Pyridoxal phosphate-dependent transferase, major domain [IPR015421] 0.4744588742793735 0.5810638817403863 0.5611974000643951 1.0 0.644077616844869 12 O15269 1 +PDZ superfamily [IPR036034] 0.4746225739979792 0.5646007041524553 0.5723453862192827 1.0 0.6536794498234805 15 O14936,Q96L92,Q9NZW5,Q14168 4 +Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069] 0.4642534864658976 0.5641640645129049 0.572642481570611 1.0 0.6536794498234805 8 Q709F0,Q92947 2 +EF-hand domain pair [IPR011992] 0.4628803886119004 0.5624040821842634 0.5738407383946584 1.0 0.6536794498234805 44 Q96AY3,O43852,Q66K14,Q8IYU8,Q14257,Q8NF37,P80303,Q15293,Q9UJS0,Q9BPX6 10 +ARID DNA-binding domain superfamily [IPR036431] 0.4410822356710611 0.5128199137553064 0.6080772985563916 1.0 0.6833608717351156 3 O14497,Q8IVW6 2 +Oxysterol-binding protein superfamily [IPR037239] 0.4435747931316665 0.5020941899767134 0.6156012669170752 1.0 0.690950259195787 5 Q9BZF3 1 +G protein alpha subunit, helical insertion [IPR011025] 0.4382342470630162 0.5009113176672625 0.616433537009047 1.0 0.6910385738842251 3 P04899,Q14344 2 +HECT, E3 ligase catalytic domain [IPR035983] 0.4458855072614579 0.4844801085512557 0.6280451778679694 1.0 0.7023383269572292 8 Q96PU5,Q96J02 2 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.4295373665480439 0.476024512947478 0.6340569143459334 1.0 0.7081975523206101 2 Q9BSJ2 1 +Sec1-like, domain 2 [IPR027482] 0.4127492877492906 0.387176709287687 0.6986253914119827 1.0 0.7709259734353647 4 O00186,Q9H267,Q96AX1 3 +Sec1-like, domain 1 [IPR043154] 0.4127492877492906 0.387176709287687 0.6986253914119827 1.0 0.7709259734353647 4 O00186,Q9H267,Q96AX1 3 +Sec1-like, domain 3a [IPR043127] 0.4127492877492906 0.387176709287687 0.6986253914119827 1.0 0.7709259734353647 4 O00186,Q9H267,Q96AX1 3 +Sec1-like superfamily [IPR036045] 0.4127492877492906 0.387176709287687 0.6986253914119827 1.0 0.7709259734353647 4 O00186,Q9H267,Q96AX1 3 +PurM-like, C-terminal domain superfamily [IPR036676] 0.4040583837664668 0.3643089545359495 0.7156273139093632 1.0 0.7849644101135 3 P49903,O15067 2 +PurM-like, N-terminal domain superfamily [IPR036921] 0.4040583837664668 0.3643089545359495 0.7156273139093632 1.0 0.7849644101135 3 P49903,O15067 2 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.3967971530249148 0.3478128495221166 0.7279807389613377 1.0 0.7947123066994604 2 Q9NVN8 1 +HAD-like superfamily [IPR036412] 0.4235556114338145 0.3289775151179598 0.7421726833028794 1.0 0.8082807014118057 17 P16615,Q969T7,Q3ZCQ8,Q9HD20,P20020 5 +HAD superfamily [IPR023214] 0.4235556114338145 0.3289775151179598 0.7421726833028794 1.0 0.8082807014118057 17 P16615,Q969T7,Q3ZCQ8,Q9HD20,P20020 5 +Band 7/SPFH domain superfamily [IPR036013] 0.4035650623885906 0.3224463101450049 0.7471146056202917 1.0 0.8117347077651748 7 Q14254,O75955,O94905,O75477,Q99623,Q9UJZ1 6 +K Homology domain, type 1 superfamily [IPR036612] 0.429055009195996 0.3163913506605056 0.7517054812126269 1.0 0.8147918750259798 27 P51116,Q96I24,P61978,Q07666,O75525,P51114,O75179,Q92945 8 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4011783024968606 0.3134788205919768 0.7539169091174696 1.0 0.8162240916891613 7 O43847,P22695,Q5JRX3 3 +Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008] 0.3854649091556799 0.2752895167009036 0.7830938179017721 1.0 0.8388984007195386 5 Q9P2J5,Q15031,P41252,Q9NSE4 4 +Papain-like cysteine peptidase superfamily [IPR038765] 0.4133822302276175 0.2593610866564316 0.7953566510015257 1.0 0.8470871648878039 23 Q96K76,Q8TEY7,P40818,Q96RU2 4 +WW domain superfamily [IPR036020] 0.3713926117908898 0.2174909097806705 0.8278257904079351 1.0 0.8705772030923647 6 Q96J02 1 +HotDog domain superfamily [IPR029069] 0.3702779757662077 0.2138376956043287 0.8306736279461719 1.0 0.8725403400076056 6 Q8WUY1,Q9NPJ3,O14734,Q9Y305,P51659 5 +Zinc finger, CCCH-type superfamily [IPR036855] 0.3673451591875087 0.1871232922844113 0.8515639661031378 1.0 0.8863611315738676 8 Q9H000,Q8IWR0 2 +S-adenosyl-L-methionine-dependent methyltransferase [IPR029063] 0.3838854267117538 0.1295045961723648 0.8969583883596441 1.0 0.9252090462607352 27 Q9BV86,Q08J23,O60678,P49327,Q8N6R0,P21964,Q86X55 7 +Sirtuin, catalytic core small domain superfamily [IPR026591] 0.3227758007117477 0.1151399233203666 0.9083342160816752 1.0 0.9337920136175966 2 Q8IXJ6 1 +Immunoglobulin-like fold [IPR013783] 0.3739830653618524 0.0938159884076607 0.925255330789257 1.0 0.9490178023953596 27 Q8IZA0,P08236,P04439,P15260,P01889,P10321 6 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3483729948399957 0.064967100992033 0.9482001945010056 1.0 0.9693417818923326 17 Q9H7Z7,Q13505 2 +Thioredoxin-like superfamily [IPR036249] 0.3623530259900063 0.0530512127974721 0.9576911032203024 1.0 0.9779540552928924 49 O75880,Q6ZRP7,Q9Y320,Q8TED1,Q8TB36,O43819,O95881,Q9H7Z7,Q8IXB1,Q96CS3,Q9H3N1,O75368,Q9H1E5,O43396 14 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.2553553134158786 0.0458588218111076 0.963422775059029 1.0 0.9827126637698882 121 P23588,Q96E39,P62995,Q15233,O60506,P51991,P22626,Q92804,P52597,P98175,P31483,Q14011,Q13151,O43390,P31942,O14979,Q96PK6,Q9BWF3,Q13242,Q99729,Q13595,Q9Y2U8,Q9UHX1,Q01844,Q01085,P31943,Q14103,P55795,P07910,Q9UBU9,P23246,Q12849,P98179,Q16629,P35637,P38159,P43243,Q07955,Q9Y6M1 39 +RNA-binding domain superfamily [IPR035979] 0.2546420120354263 0.0346460109265463 0.9723620120905916 1.0 0.9907288500967472 122 P23588,Q96E39,P62995,Q15233,O60506,P51991,P22626,Q92804,P52597,P31483,Q14011,O43390,P31942,O14979,Q96PK6,Q9BWF3,Q13242,Q99729,Q9UHX1,Q01844,Q01085,P31943,Q14103,P55795,P07910,Q9UBU9,Q16629,P35637,Q71RC2,P38159,Q07955,Q9Y6M1 32 +Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080] 0.3070613409415103 0.0297503995503947 0.9762661166617173 1.0 0.9936026958699165 8 P26640,Q9P2J5,Q15031,P41252,Q9NSE4,P49589,P54136 7 +Beta-grasp domain superfamily [IPR012675] 0.2980263850796925 0.0198412743321187 0.9841699922000284 1.0 1.0 7 Q9BW92,Q9NTK5,P21912 3 +Zinc finger, CCHC-type superfamily [IPR036875] 0.2833989733896749 0.0098147315998322 0.9921691029119624 1.0 1.0 5 Q9NUD5 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.275997150997149 0.0060245593198355 0.9951931262109128 1.0 1.0 4 P42345,O00443,P42356 3 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2300f23490d2efb0fb3c2624cd18c5e28d1acfbe --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "5-formyltetrahydrofolate cyclo-ligase-like domain superfamily [IPR024185]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "B30.2/SPRY domain superfamily [IPR043136]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "Beta-trefoil domain superfamily [IPR036358]", "BolA-like superfamily [IPR036065]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PBDC1-like domain superfamily [IPR023139]", "PCGF Ub-like fold discriminator superfamily [IPR038227]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S1, PA clan, chymotrypsin-like fold [IPR043504]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Quinolinate phosphoribosyl transferase, N-terminal domain superfamily [IPR037128]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RBP-J/Cbf11, DNA binding domain superfamily [IPR037095]", "RGS domain superfamily [IPR036305]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Receptor L-domain superfamily [IPR036941]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S26e superfamily [IPR038551]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIID subunit TAF5, NTD2 domain superfamily [IPR037264]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Tctex-1-like superfamily [IPR038586]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tma16 superfamily [IPR038356]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WIBG, N-terminal domain superfamily [IPR036348]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YEATS superfamily [IPR038704]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8A", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATXN10", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCL2L13", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRD1", "BRD2", "BSG", "BTF3", "BUB1B", "BUB3", "BZW1", "BZW2", "C1QBP", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKAL1", "CEBPZ", "CELF1", "CEP170", "CEPT1", "CERS2", "CFL1", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHTF18", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COA7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCUN1D1", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FKBP10", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GORASP2", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INTS1", "INTS14", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIAA0368", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MANBA", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "METTL13", "METTL16", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL47", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP3", "NCDN", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA9", "NDUFAF1", "NDUFS1", "NDUFS3", "NDUFV2", "NECAP2", "NEDD4L", "NEK9", "NELFE", "NENF", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4KA", "PICALM", "PIK3C2A", "PIK3R4", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA1", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RIPK1", "RMDN1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP12", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A11", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SBNO1", "SCAF11", "SCAF4", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDAD1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC3A2", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMU1", "SMYD3", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRAP", "STRBP", "STUB1", "STX12", "STX4", "STX5", "STX7", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TECR", "TELO2", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFRC", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "TIA1", "TIAL1", "TIGAR", "TIMM44", "TIMM50", "TJP1", "TK1", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM14C", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL5", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WFS1", "WIZ", "WNK1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMYND8", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB7", "ABCC1", "ACAD11", "ACOT13", "ACOT8", "ACOT9", "ACOX3", "ADPGK", "AGL", "AIFM1", "ANAPC5", "ANAPC7", "ANKLE2", "ANKRD17", "ANXA1", "ANXA11", "ANXA3", "ARID1A", "ARID3B", "ATP13A1", "ATP2A2", "ATP2B1", "BSG", "CALU", "CAMK2G", "CARM1", "CARS", "CASK", "CERS2", "CIRBP", "CLUH", "CNNM4", "COA7", "COMT", "CPNE1", "CRTAP", "CYB5B", "CYB5D2", "DERL1", "DHCR24", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "EIF3L", "EIF4B", "EMD", "ERAL1", "ERAP1", "ERLIN1", "ERLIN2", "EWSR1", "EXOSC5", "EXOSC8", "FAF2", "FASN", "FDFT1", "FKBP10", "FKBP5", "FLOT1", "FLOT2", "FNTB", "FOXRED1", "FUBP3", "FUS", "FXR1", "FXR2", "GAK", "GALNT1", "GCDH", "GDAP1", "GNA13", "GNAI2", "GNL3L", "GPHN", "GPX8", "GRSF1", "GUSB", "HLA-A", "HLA-B", "HLA-C", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPR", "HSD17B4", "HSDL2", "HSPB1", "IARS", "IARS2", "IFNGR1", "IGF2BP2", "IQSEC1", "ITCH", "KDM1B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "LANCL1", "LARP4", "LARS", "LARS2", "LEMD3", "LNPEP", "LPCAT1", "LTA4H", "MAPRE2", "MATR3", "MAU2", "MCL1", "METTL13", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MICU1", "MICU2", "MKRN2", "MPP2", "MPP6", "MTCH1", "MTCH2", "MTMR6", "MTOR", "MTX1", "NAP1L1", "NAP1L4", "NEDD4L", "NONO", "NPEPPS", "NRDC", "NSUN2", "NT5C3B", "NTMT1", "NUCB2", "NXF1", "OLA1", "OSBPL6", "P3H1", "P3H4", "P4HA1", "PANK4", "PCYOX1", "PDE6D", "PFAS", "PFDN5", "PFDN6", "PGRMC1", "PGRMC2", "PHB2", "PI4KA", "PIK3C2A", "PITPNB", "PITRM1", "POLR1C", "POLR2B", "POLR3B", "PPAT", "PRKAR2A", "PRKCB", "PRMT3", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSMD11", "PTGES2", "PTPN11", "PUF60", "QSOX2", "RAPGEF2", "RARS", "RBM10", "RBM14", "RBM3", "RBM4", "RBMX", "RBMXL1", "RCN1", "RCN2", "RMDN1", "SAMHD1", "SCO1", "SCO2", "SDHB", "SEC14L2", "SEC63", "SEPHS1", "SFPQ", "SGTA", "SH3BGRL", "SIRT2", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SMYD3", "SNX27", "SPTLC1", "SRSF1", "SRSF7", "SRSF9", "STARD3", "STARD7", "STOML2", "STXBP3", "SYNCRIP", "TAF15", "TARS2", "TBC1D9B", "TBCB", "TBCE", "THEM6", "THOP1", "TIA1", "TIAL1", "TIMM44", "TIMM50", "TMED2", "TMED7", "TMPO", "TMX1", "TMX2", "TMX4", "TRA2A", "TRA2B", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TXNDC12", "TXNL1", "UNC119", "UNC119B", "UQCRC2", "USP28", "USP33", "USP47", "USP8", "VARS1", "VBP1", "VDAC1", "VDAC2", "VPS33A", "VPS33B", "WFS1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H7A", "ZCCHC3"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f2fb8b0188e2674d0e142a44f4ee941ea728aad1 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e59094b15a5024fa9c5e3b1cfc5d8fe501dbc9916c1901b3670711ba14057264 +size 62864 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..440404fe976e3da4873185fa5bee3d71cd2f3523 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.25 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7ed4d0856f25a025523de639281978b2c226d3b8 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..fda6b565b3b8db5de7802faa85bcc002a5d6d535 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.6593489306613693 1.499653157996053 0.1337042701961508 0.4367973434885177 0.1782723602615344 5 Q9HD20,P16615,P20020 3 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cf76aee8f45c986f98f417a28f49c7913b684d87 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "EIF5A", "FASN", "LRP1", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP2A2", "ATP2B1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1b7de153b079a1c26968ba9e55d0cfb8a4d1a948 --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed4014ff5a37afb099b21a2ec3b12591762082c9cd0f1b5aaa51952e793be751 +size 185349 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a7de5bb6d189f5099479205b30e348acbc638238 --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b0a8b49b905b8f44d9b53e9646d131983e3d7d73509f4e8e1ad70136aa7261b +size 143388 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..aa64de6815eeff733464d044025bcb51bb8f2975 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6000234d4d141f54ea99ad9e1139e83c0c5f532d83145b30e745e8b17a9d7bd8 +size 72444 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e8cffa22877484ae3d5e89bc4a0b80854ecae59f --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 10 19 2.133132555493161 0.0329138538362077 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0001334964242414 0.0136970422924113 0.00553293278753 2.8354518268714176e-05 1.1521546305420906e-06 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b55722bf83ca8f12a0728bef0606beae98119b94 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 74, + "title": "Average number of proteins per term", + "value": 5.108108108108108 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b16eff8f41f5a30d9573c49cebb370f7c3b34fe8 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2d688c0e0c9e22036efa635098c376ef1c2e25e5 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7923985085228474 2.133132555493161 0.0329138538362077 0.915972395625979 0.1082830124673919 19 Q70HW3,Q9NZJ7,O43772,Q9HC21,Q9UJS0,Q00325,Q9Y619,Q9Y6C9,Q9H2D1,Q9UBX3 10 +HEAT repeat [IPR000357] 0.6957039083661557 1.6752398447881385 0.093887182771553 0.9993215962317932 0.2241177911320944 4 P30154 1 +Annexin repeat [IPR018502] 0.6161361271243933 1.2831073210839974 0.1994544792212313 0.9999999291130386 0.304239860692917 7 P12429,P04083,P50995 3 +HEAT, type 2 [IPR021133] 0.3235344561879998 0.0430600216943735 0.9656536877877422 1.0 0.9788818204971632 11 Q9BU89 1 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..9b4f3ed6ed62c8a3e2b49a0acbc59299dd2a7ebc --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Furin-like repeat [IPR006212]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMCX3", "ARPC1A", "ASPH", "BCOR", "BIRC6", "BOP1", "BUB3", "CAST", "CDC16", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1C", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "EDC4", "EHMT1", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HTT", "HUWE1", "IFIT5", "IGF1R", "IGF2R", "IPO4", "IPO5", "JUP", "KAT7", "KDELC2", "KDM2A", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRP1", "LRPPRC", "LRRC40", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MPDU1", "MPHOSPH8", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NLE1", "NOL10", "NOP2", "NOP9", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "PAFAH1B1", "PAK1IP1", "PDCD11", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP5C", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP5", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SGTA", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SRP72", "STIP1", "STRAP", "STUB1", "SUGT1", "SYNE2", "TAF5", "TAGLN2", "TBL2", "TBL3", "TEX10", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TP53BP2", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WFS1", "XAB2", "XPO1", "YTHDC2"], "leading_proteins": ["ANXA1", "ANXA11", "ANXA3", "DOHH", "MTCH1", "MTCH2", "PPP2R1B", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f31cb712e627a7e3324e11fda847e31879470761 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Mitochondrion organization", "2": "Ion transmembrane transport", "3": "Ion transport", "4": "Cation transport", "5": "Cation transmembrane transport", "6": "Protein targeting", "7": "Inorganic ion transmembrane transport", "8": "Mitochondrial transport", "9": "Cellular respiration"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..43633816442b8c3f713c54264448a668dfd9e532 --- /dev/null +++ b/msigdb_gobp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ac41e2e016e082909293a87ca8d23f80b61d4c9e73f5919aa32eec2c6f96be1 +size 217046 diff --git a/msigdb_gobp/advanced/plot_1.png b/msigdb_gobp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ee617301f18adccb29956aebd1d7f934885d16d9 --- /dev/null +++ b/msigdb_gobp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:86ce91ea42dac79bdaf7893faa7b57df7c8c5c565879e55d5b93e3da5a00e480 +size 217118 diff --git a/msigdb_gobp/advanced/plot_2.png b/msigdb_gobp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..bc651468609667457fc4ca59c596395e21b3b4c4 --- /dev/null +++ b/msigdb_gobp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e5cfff550e35bb98d293154f0118bab6900cfe54d58c57e0293a1c705508b7c0 +size 216964 diff --git a/msigdb_gobp/advanced/plot_3.png b/msigdb_gobp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4c5db67064da4192b3a8b6715fd8703af8dc3459 --- /dev/null +++ b/msigdb_gobp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84529ade0d2eba21f654bec9fe47c07bf1b78b370cf89eab10a995f098f26245 +size 219680 diff --git a/msigdb_gobp/advanced/plot_4.png b/msigdb_gobp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..79c8ef293151487a6f65b9139e5497dc58d00aad --- /dev/null +++ b/msigdb_gobp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d31e08e09df84acdb07513623f59f27d984b379c94de75903a3dfedb8d543188 +size 213913 diff --git a/msigdb_gobp/advanced/plot_5.png b/msigdb_gobp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..e38a9788bea6f447b6335de53bb87ddee49acec2 --- /dev/null +++ b/msigdb_gobp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:802e6f71c334bcd9a490e910d0e6785c67d7fbd461ab5a9ae6c7ff2ff3b6b7b2 +size 213109 diff --git a/msigdb_gobp/advanced/plot_6.png b/msigdb_gobp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..268f03f807808412aaacbac1444cc8958ba1b8a7 --- /dev/null +++ b/msigdb_gobp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa87ad13120500f7420fba0689648987f677e432cf31a7a5a1296cf6a3ea397c +size 209174 diff --git a/msigdb_gobp/advanced/plot_7.png b/msigdb_gobp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..6f6b513c01c6939c882a8339c0bacdf89e7211fb --- /dev/null +++ b/msigdb_gobp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:392bb68a6d822b935d447b4226567f686999b894df571956e6a58dad09d27329 +size 212923 diff --git a/msigdb_gobp/advanced/plot_8.png b/msigdb_gobp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..41dab44cd31ba37c24fdeba1afb12f8bc50c6d84 --- /dev/null +++ b/msigdb_gobp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79cccdf771434ce0d8c414be24225e072ea5204567c0d7668389814f7e377624 +size 205544 diff --git a/msigdb_gobp/advanced/plot_9.png b/msigdb_gobp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..47a13332d7d58c1546e73d32fcb84266759ca5c6 --- /dev/null +++ b/msigdb_gobp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0316fdf9ee1988237265ba82e611e6b0a37629928512abda22a1a6270264aac2 +size 206665 diff --git a/msigdb_gobp/basic/idx2term.json b/msigdb_gobp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e36ff0c68e514a699b533a622e1875b90de9b30 --- /dev/null +++ b/msigdb_gobp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Mitochondrion organization", "2": "Ion transmembrane transport", "3": "Ion transport", "4": "Cation transport", "5": "Cation transmembrane transport", "6": "Protein targeting", "7": "Inorganic ion transmembrane transport", "8": "Mitochondrial transport", "9": "Cellular respiration", "10": "Energy derivation by oxidation of organic compounds", "11": "Cytochrome complex assembly", "12": "Anion transport", "13": "Membrane organization", "14": "Calcium ion import", "15": "Aerobic respiration", "16": "Protein transmembrane import into intracellular organelle", "17": "Anion transmembrane transport", "18": "Intracellular protein transport", "19": "Negative regulation of multicellular organismal process", "20": "Protein transmembrane transport", "21": "Mitochondrial transmembrane transport", "22": "Response to endoplasmic reticulum stress", "23": "Metal ion transport", "24": "Mitochondrial respiratory chain complex assembly", "25": "Intracellular protein transmembrane transport", "26": "Atp metabolic process", "27": "Inorganic anion transport", "28": "Positive regulation of catabolic process", "29": "Endomembrane system organization", "30": "Ion homeostasis", "31": "Peptide catabolic process", "32": "Nitrogen compound transport", "33": "Regulation of cell death", "34": "Regulation of immune response", "35": "Cristae formation", "36": "Antigen processing and presentation of peptide antigen via mhc class i", "37": "Positive regulation of cell death", "38": "Cellular homeostasis", "39": "Programmed cell death", "40": "Macroautophagy", "41": "Antigen processing and presentation of peptide antigen", "42": "Negative regulation of cell death", "43": "Chemical homeostasis", "44": "Positive regulation of macroautophagy", "45": "Nadh dehydrogenase complex assembly", "46": "Apoptotic signaling pathway", "47": "Response to oxidative stress", "48": "Regulation of autophagy", "49": "Protein catabolic process"} \ No newline at end of file diff --git a/msigdb_gobp/basic/plot_0.png b/msigdb_gobp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b361c13e295c5c8d4a4b8550015242e2b69d971b --- /dev/null +++ b/msigdb_gobp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8cc4b37cf50198c7a31f812ba0adcd9b9ebf399f2cc9ca7b0b66ac14aeba4ec +size 139901 diff --git a/msigdb_gobp/basic/plot_1.png b/msigdb_gobp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e351736f65030cc8b434843c02f16baa89624508 --- /dev/null +++ b/msigdb_gobp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c7cf16602de59406dcb81c56c28177f117451df181a1d09c62598c59c5fd72b2 +size 140484 diff --git a/msigdb_gobp/basic/plot_10.png b/msigdb_gobp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..14b9a1f1ef965264986d6091505a92a0b7dc62b2 --- /dev/null +++ b/msigdb_gobp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:560f04f99e25e8c0805322782bc0f4d58ef074f2ad928a363c4949b4c8aa0262 +size 148619 diff --git a/msigdb_gobp/basic/plot_11.png b/msigdb_gobp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..96076b6dd89a36976aa05e8676484c7c314f7ea8 --- /dev/null +++ b/msigdb_gobp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c15cadfe3bb4d65c218744ab395f3048c1301fc11dc1cc6aaf744e24403aac6f +size 138976 diff --git a/msigdb_gobp/basic/plot_12.png b/msigdb_gobp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..7e6f54ba796acf731a855a8352fea08ee5d3d9ec --- /dev/null +++ b/msigdb_gobp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ae441e5835449512241aee6bd5118522c8bbbbdc82c88297ce34a22775917f0 +size 133057 diff --git a/msigdb_gobp/basic/plot_13.png b/msigdb_gobp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..fbd7d9004e9a6e50cd5f3964365508bb4280c34d --- /dev/null +++ b/msigdb_gobp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d272a5c33e0bdcffd6f510c8dacf59ae1db615ae23c6c8f7ff2b28096e5ae7dd +size 142438 diff --git a/msigdb_gobp/basic/plot_14.png b/msigdb_gobp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..79be2e9494f40b20d23ddb2394fa46d43f7f43f4 --- /dev/null +++ b/msigdb_gobp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a2f2bc5224263c2990bea0ffc5f040cd0f743cf1bcc2452788c4e910ff214f5 +size 129861 diff --git a/msigdb_gobp/basic/plot_15.png b/msigdb_gobp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..edad4586a31ebeff72eace61b29b95992b09efdb --- /dev/null +++ b/msigdb_gobp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9477ea7a24c35d2c6087dd436f1d620906e7e0641eadc0bb3b57628587300233 +size 143038 diff --git a/msigdb_gobp/basic/plot_16.png b/msigdb_gobp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..d108eaa777ce913c515a37b5cdf9dab5914e9ea2 --- /dev/null +++ b/msigdb_gobp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8af1df1bca9ee11568c6af1a8b147f3f95e3322f5f047c424479ab52f83194ee +size 139666 diff --git a/msigdb_gobp/basic/plot_17.png b/msigdb_gobp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..d8c49d30352d2d081409625785a8be61abc8c560 --- /dev/null +++ b/msigdb_gobp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f07ea691d79cc4a85d0fe8f9dffe2f275ac2e7a635b78c6483e0a5f981e75f6 +size 137176 diff --git a/msigdb_gobp/basic/plot_18.png b/msigdb_gobp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..feff1303081ca41aaab42adbb4a58584815436f2 --- /dev/null +++ b/msigdb_gobp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ffbe6db40ff71f84831a83a8db613a55e951b36963c3989e34a5a87eb7b3447e +size 136853 diff --git a/msigdb_gobp/basic/plot_19.png b/msigdb_gobp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..845a6db345ab7d97f116eb9286c8f8982808560b --- /dev/null +++ b/msigdb_gobp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c2dca4156d958a8a508f6216af3394c1675512cf0f396dd661335cf2345c5ef +size 147502 diff --git a/msigdb_gobp/basic/plot_2.png b/msigdb_gobp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..59eabb4ebb509eed8ed0eb5053048f38e3ced886 --- /dev/null +++ b/msigdb_gobp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0bb9714f50a39c9beb25b686070875a5fa6acabdf4a23b379ea59e1848d0a544 +size 143451 diff --git a/msigdb_gobp/basic/plot_20.png b/msigdb_gobp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..45d64f9e33942621d3d1d5dc49ca412d83422553 --- /dev/null +++ b/msigdb_gobp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac160ae89b0e7a72beae77c81d26220a4aa591acc98d94945c9baea7d8c19cb6 +size 138142 diff --git a/msigdb_gobp/basic/plot_21.png b/msigdb_gobp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..514c63628404b2de61bc525e70987c8a686a88df --- /dev/null +++ b/msigdb_gobp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:26850e72c422b3e86ecb9073e8e5c1c93c3f1dd9f4983d097e7606abf64a72e5 +size 138855 diff --git a/msigdb_gobp/basic/plot_22.png b/msigdb_gobp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..bcd6332597680a8fb4f00cc77490b2afde17a196 --- /dev/null +++ b/msigdb_gobp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2314de3dd0a32cb331e6fe3a9bcfa8d4e1c4ab971aed274f4a7f43ff49f22f46 +size 143546 diff --git a/msigdb_gobp/basic/plot_23.png b/msigdb_gobp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..ffcb14fec8a45d6e55c205bda63bfb9a2d76fa89 --- /dev/null +++ b/msigdb_gobp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97dc4d2f6aac51c090ad7a51fab8d9af7d105d158a8cd689f936b649a6ae403a +size 138606 diff --git a/msigdb_gobp/basic/plot_24.png b/msigdb_gobp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..867aeee23f927992845b4f2a6133f7ef9201f3dc --- /dev/null +++ b/msigdb_gobp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:afad619289bb29eb834a0e0f709ffb194750ae5cee344517610141f685fc8633 +size 140469 diff --git a/msigdb_gobp/basic/plot_25.png b/msigdb_gobp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..209be2ba379e22cac65b992d73873491bb5a517f --- /dev/null +++ b/msigdb_gobp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b08179b78316808176f1baa59160effb9202b3af891d8843a050d7c50ee23fb9 +size 136238 diff --git a/msigdb_gobp/basic/plot_26.png b/msigdb_gobp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..7c6a5f66e28a1ee2111f5aa842af16a4a3a2a49a --- /dev/null +++ b/msigdb_gobp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3af987fa0a6cdfc70d54e7a53c095227393b75982ad8452e16d25f7e55a4e7a +size 141017 diff --git a/msigdb_gobp/basic/plot_27.png b/msigdb_gobp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..58514cdd4df5fe3e4b17c6e02a633b06a800699e --- /dev/null +++ b/msigdb_gobp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e5691c6df76289fa53086356067e15adc38bb68515528fdf96583cf6f163bdac +size 121543 diff --git a/msigdb_gobp/basic/plot_28.png b/msigdb_gobp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..f81a67fa9142ce47eb58f47d93c5f548f55716bb --- /dev/null +++ b/msigdb_gobp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:063310feeea1a2890c73ed0b71ca94a8a89568a2074d3c0a9ff35332aa0a54ee +size 151250 diff --git a/msigdb_gobp/basic/plot_29.png b/msigdb_gobp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..246a3d76b8ce485fba4febaaefd71e8a5f994877 --- /dev/null +++ b/msigdb_gobp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53bb9f98d5e64f1653bfb6b2a236eb5214a860cb55478ff05ab246eeeae06a78 +size 142557 diff --git a/msigdb_gobp/basic/plot_3.png b/msigdb_gobp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..83b13c7eeed5a4128f33d42b7a9b7dbbe7b14080 --- /dev/null +++ b/msigdb_gobp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1d14621e99b6e13031e60061c5ecd974ac6bb793e7952ec9110ca9015e37b00 +size 131345 diff --git a/msigdb_gobp/basic/plot_30.png b/msigdb_gobp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..21fef396da0bfeae8e042db24950742bb8997ca2 --- /dev/null +++ b/msigdb_gobp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc89009b0fcdd97751da1c397a7dd49c3a5b4dbf62e1b9bc51b7edd76fd96558 +size 139097 diff --git a/msigdb_gobp/basic/plot_31.png b/msigdb_gobp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..aa66ca76deeb798ed982a2cc64d5ab18e765ba8f --- /dev/null +++ b/msigdb_gobp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3c65973bc3a0c6cc67961d23258ee642722dbc793001c9ae96364eea9ac31355 +size 136287 diff --git a/msigdb_gobp/basic/plot_32.png b/msigdb_gobp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..71d1e3d402b3e0ce683e8dc1eba0e91ad63b0885 --- /dev/null +++ b/msigdb_gobp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58f1afbe13b64d2aa19e668c98b394149ba7b7067ab6fafcdd5d251ce65503a0 +size 139346 diff --git a/msigdb_gobp/basic/plot_33.png b/msigdb_gobp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..9c623897d7ac2c29e61964c27e0f26f1e5e551ea --- /dev/null +++ b/msigdb_gobp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b874125ffefdf6b2bfb5f78869e183a5f7e21224204e16f67d0fa5b36180f94 +size 138967 diff --git a/msigdb_gobp/basic/plot_34.png b/msigdb_gobp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..4eca8b7f2314ffe01669c798c34d35fa1e7f3481 --- /dev/null +++ b/msigdb_gobp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:977ee8c972937cb39466e9bb84593ccebba61ee3639d789225f1047f243ed7ff +size 146768 diff --git a/msigdb_gobp/basic/plot_35.png b/msigdb_gobp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..350c954071f5fa7e11e671f66155d03860f9571b --- /dev/null +++ b/msigdb_gobp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:13535fceef8d342ee11c54b29e4a5301cf51cdd87d355a72dd36ed0f3719adc1 +size 128824 diff --git a/msigdb_gobp/basic/plot_36.png b/msigdb_gobp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..82c43c7e446bbdfc245c368c8f5a5952812365c5 --- /dev/null +++ b/msigdb_gobp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:728cd3d1893db819d84e7e6eac180dc987e6faa6ea21d4464064810dd6deb4f7 +size 140121 diff --git a/msigdb_gobp/basic/plot_37.png b/msigdb_gobp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..e98229d23324fb9d852ed570b18cdb7466cb2ee4 --- /dev/null +++ b/msigdb_gobp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fc9099a5910a619f32f0c9d6b8741d7a981b64760ca682321739193fb30a2c3 +size 146111 diff --git a/msigdb_gobp/basic/plot_38.png b/msigdb_gobp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..62e791c02d386350f3b26673d8f018fed8ff3f29 --- /dev/null +++ b/msigdb_gobp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c96a083ee19b028cee54cc0375bf94dfb992e52d9c25e75f1a444b41d5f31833 +size 138407 diff --git a/msigdb_gobp/basic/plot_39.png b/msigdb_gobp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..d23ec2a50c0f36049563cea51c33486e18fcc04d --- /dev/null +++ b/msigdb_gobp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cccb9aba5d2a2d527f7b1ff439a22e29d70aa3558e4903794b88d6843e7d834 +size 136906 diff --git a/msigdb_gobp/basic/plot_4.png b/msigdb_gobp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..09de821243079554097fcedbcf85adfaae8a168a --- /dev/null +++ b/msigdb_gobp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:471b4a34d56f66c56d3f53573163601d9572abe3bb12a1638e169a1cb4b50262 +size 141535 diff --git a/msigdb_gobp/basic/plot_40.png b/msigdb_gobp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..347ca3c1d81d37d3a44909d4c788228595cfb457 --- /dev/null +++ b/msigdb_gobp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff75e911b4bc6a7e34a1205df65fa33e5f95d43bea0983c0c09b42ecb989bb3d +size 138523 diff --git a/msigdb_gobp/basic/plot_41.png b/msigdb_gobp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..04b95408e4354ec7c4cc203e1e512561bfc7de2e --- /dev/null +++ b/msigdb_gobp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5140ac6251ee06d1958df65011905c4394c586c8bd6f1841da75d73aea90051a +size 137978 diff --git a/msigdb_gobp/basic/plot_42.png b/msigdb_gobp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..3c43c80c646ada65549a8d94e2fc2dae04247b01 --- /dev/null +++ b/msigdb_gobp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed210ed8cd27947f3ef659372994997c731199706dd96ec1f9e27fddf138d606 +size 144692 diff --git a/msigdb_gobp/basic/plot_43.png b/msigdb_gobp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..c4bd680a2ad21354545eb7cb7ea1718d824a385e --- /dev/null +++ b/msigdb_gobp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d00a8b9021ab94918f4dcaa9d578e8c18fcd391c7824531a34ebfe955a22c930 +size 138623 diff --git a/msigdb_gobp/basic/plot_44.png b/msigdb_gobp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..fb7fabfb6dffdb2210dba16f301ea9617e0988e0 --- /dev/null +++ b/msigdb_gobp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5af0e544ac86204f157a5bccbd2f1e9a8419f1889a6893974661e393931314cf +size 141803 diff --git a/msigdb_gobp/basic/plot_45.png b/msigdb_gobp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..6c157abd0e1683dfee5fc6ff369491fe83d73e99 --- /dev/null +++ b/msigdb_gobp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:48271d5f87fd6b47f6f072acd1f3ec9fe5f7e605fe693eab396552fb5f4caa04 +size 142022 diff --git a/msigdb_gobp/basic/plot_46.png b/msigdb_gobp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..6214e8e13b76cac94d3aafa74e76b2c4a26ea634 --- /dev/null +++ b/msigdb_gobp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:93b852699958efafba79b68b0c2367d44560d5de128defa1c5311c31956b4bb3 +size 145963 diff --git a/msigdb_gobp/basic/plot_47.png b/msigdb_gobp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..cd87f19dc90b2e45577c892f49fd329e966ce69b --- /dev/null +++ b/msigdb_gobp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b60dfa8f7077601c8ec671df7195a4789379047a343beb588515c44ed186aa34 +size 146666 diff --git a/msigdb_gobp/basic/plot_48.png b/msigdb_gobp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..1e22d96d25dc8f08fd6dfb5cff9e56a417d9ca95 --- /dev/null +++ b/msigdb_gobp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fc09967a6d7dd42fb0f35a47239441a5716756ba3c3159ca54b9126a0c369cd +size 142120 diff --git a/msigdb_gobp/basic/plot_49.png b/msigdb_gobp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..accb9cc5099658d0a921809e1b39b2a5b41ddaa6 --- /dev/null +++ b/msigdb_gobp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e2c18715a8d37d8fda031e6aa8f49d08bf6560f1147c113874eee2c515327ea7 +size 142509 diff --git a/msigdb_gobp/basic/plot_5.png b/msigdb_gobp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..46b79eb91fe3d09013235f99367858a0c4c71156 --- /dev/null +++ b/msigdb_gobp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:40709a522515ddf34a67966bcb9b1d8662dd2c98a03a700f0123158b1a2722be +size 146582 diff --git a/msigdb_gobp/basic/plot_6.png b/msigdb_gobp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..e86891209d8421b29b0533269bb414f2d7e33099 --- /dev/null +++ b/msigdb_gobp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:496103e88adf5a784ec73afd9d7e329d2329d34269eb228842cab90d536d5f94 +size 142264 diff --git a/msigdb_gobp/basic/plot_7.png b/msigdb_gobp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..0033c553eb1f80e5c7aef3ae9a2337b21519aae3 --- /dev/null +++ b/msigdb_gobp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:56c99edfe0515e0e24cdd0dfca81cf477b7abf5004847b1d980a1aa564c485b1 +size 150934 diff --git a/msigdb_gobp/basic/plot_8.png b/msigdb_gobp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..730b6a99c366ec3cb5b854fb6246f3c050731833 --- /dev/null +++ b/msigdb_gobp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a3eaef5b1be9224087da4c84c74bb41976d2e0f609eacce181be5bf89504f07 +size 139995 diff --git a/msigdb_gobp/basic/plot_9.png b/msigdb_gobp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..3031f5c126efb37e7f510c63ab83298c83f076d0 --- /dev/null +++ b/msigdb_gobp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0aa5e0076aa767efd739eb06dae589a8d2f02601e9b7993961ef49ccba4e4b48 +size 141439 diff --git a/msigdb_gobp/consensus.joblib b/msigdb_gobp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..d4f51601d428302197e1dd26bdc1fced03aa19ef --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b9a41f364e5ae83823dd69a3a3c64df9a8a1cc6dec88faffde4ed0a3865a0d47 +size 597356 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4af2ecc14cc09fbbd45f2d680334712870bce120 --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,73 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transmembrane transport 66 187 5.306030119263454 1.1203845305850289e-07 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 7.440685656151208e-08 0.0001606735243173 5.302219872230687e-07 7.82622781015395e-08 7.51757219418728e-10 +Mitochondrion organization 36 155 4.594323466263173 4.3415548589553765e-06 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 5.28361901427443e-08 5.377830354354308e-07 6.094472005286434e-07 3.730290623450159e-09 1.7503425761996569e-07 +Ion transmembrane transport 44 138 4.561007748129047 5.090870226265309e-06 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 8.627957107725086e-06 0.0051922940908961 9.944478448510458e-05 0.0001019450878114 1.795276661008256e-06 +Ion transport 55 187 4.1527990482259405 3.284331325725809e-05 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 8.22473396769118e-05 0.0275105950473259 0.0008841592536808 0.0012635112119426 7.6066093075301725e-06 +Cation transport 39 140 3.572389556137985 0.000353738683561 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.0144102807727248 0.2049440017828421 0.0194901677966796 0.0165145667809775 0.0010883558942636 +Cation transmembrane transport 31 107 3.538882287901665 0.0004018249903452 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0107468198818363 0.0983453945097603 0.02582531067498 0.0183743758498551 0.0012725535521377 +Protein targeting 24 99 3.274814238828604 0.001057314740136 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 0.0004905725944783 0.0001566733401048 2.4795332817630947e-05 0.000361151327296 8.47743088056497e-05 +Inorganic ion transmembrane transport 26 98 3.118478992380004 0.0018178710079068 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0153277997204818 0.0764214663672128 0.0160285035525861 0.0364820146963056 0.0086724606829118 +Mitochondrial transport 24 77 2.925167548656282 0.0034427080844476 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 1.4206651846583549e-05 1.0357624154063389e-06 4.355766731388173e-06 2.911883135638024e-06 1.507120619652375e-07 +Cellular respiration 21 91 2.7314455647582405 0.0063057156886041 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 0.0008970038959173 0.0117896569513851 0.0021212312663664 0.0020124241157655 4.273566554426358e-05 +Positive regulation of mitochondrial translation 1 5 2.5233304915235397 0.0116249090420104 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.0163228381361592 0.0021914548918381 0.0086772133501052 0.0491545726752397 0.1630814235328921 +Negative regulation of developmental growth 0 7 2.443953789619668 0.0145272871434427 2.6067961165048543 10.118932038834952 0.4177621670448362 0.5151603515616955 2.0822300468824904 1.7258544598953018 0.8590834947670382 0.302034516552393 0.5140510672551 0.225458320485449 0.4040169080940247 0.7320297781445764 0.9324291724885764 +Energy derivation by oxidation of organic compounds 25 109 2.442371205874749 0.0145911349189622 30.652912621359224 122.18932038834951 0.2541815110246533 0.5071130371174295 12.61138398748304 8.311769788309597 1.4201467433346076 0.3884313364311733 0.0049469030990045 0.0270033829491375 0.0083544602520331 0.0058252678926633 0.000124864957028 +Mitochondrial cytochrome c oxidase assembly 3 5 2.399670912867466 0.0164098171746742 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 0.2543811559285687 0.0987043131013681 0.1898352204968973 0.0970188007029606 0.0200033311952484 +Cytochrome complex assembly 6 8 2.392158038295956 0.0167496283667762 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.0741572201711518 0.1484538203623246 0.277861461810767 0.0085651992096032 0.0010440793255692 +Negative regulation of axonogenesis 0 5 2.381567712347513 0.0172391211024409 1.4951456310679612 5.604368932038835 0.5111440741336667 0.4854399038461674 1.2969253139844743 1.1453919241926127 0.8397552514706781 0.2885954943863668 0.3299756870465455 0.1321770275159086 0.2496255286594674 0.5184405571056024 0.7757910097923159 +Response to food 2 5 2.373826684457392 0.0176048118567022 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 0.1591808937815334 1.0 0.1169218221283287 0.2712176839291556 0.0225979674873623 +Respiratory chain complex iv assembly 4 6 2.337507958933575 0.0194127875870182 2.7475728155339807 6.451456310679611 1.036831430168084 0.2562354664331627 1.605321530277248 1.669274831081891 1.262804896468415 0.2848709091577191 0.2836730084964235 0.1114021565620111 0.2127898194125335 0.1203326107508497 0.0062616815035888 +Telencephalon glial cell migration 1 7 2.332181842410732 0.0196911269774784 2.233009708737864 7.087378640776699 0.5492028042680085 0.4450257844422223 1.419037575500536 1.003458060873564 0.9197644287936114 0.2957414671751674 0.0207808863220497 0.0771453392642774 0.0111011801010317 0.0617128865328283 0.1985866733922443 +Cerebral cortex radially oriented cell migration 1 7 2.332181842410732 0.0196911269774784 2.233009708737864 7.087378640776699 0.5492028042680085 0.4450257844422223 1.419037575500536 1.003458060873564 0.9197644287936114 0.2957414671751674 0.0367196691105464 0.1029565435856987 0.0199028792923938 0.1046379555654025 0.3080842130268088 +Cellular response to increased oxygen levels 1 6 2.330664603586911 0.0197710520297571 1.6504854368932038 6.385922330097087 1.138869139630967 0.2726341581961526 1.2184562719610088 0.8029653015671253 0.9206381175249092 0.2739573544488438 0.0105293638672671 0.0013899505248691 0.0055563644779973 0.0323840811666381 0.018020673376298 +Protein import into mitochondrial matrix 4 9 2.327731267757449 0.0199263777425282 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0163228381361592 0.0021914548918381 0.0086772133501052 1.8964525874379697e-05 0.0005289198821125 +Anion transport 23 62 2.3164816089396463 0.0205319874502474 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 0.0013353856304222 0.0142646004278545 0.0029148698196075 0.0032121107226409 3.682848707849801e-05 +Regulation of mitophagy 1 5 2.3153734365027465 0.0205925039595926 2.033980582524272 6.730582524271845 0.7938894190377023 0.2859156513857533 1.5052692819802862 1.0417203147023346 1.2011910390869405 0.2760404746280959 0.1478851848182938 0.0550816697898294 0.1084298440104649 0.2532529321952443 0.1125747569923622 +Membrane organization 62 207 2.313520292872754 0.020694050362086 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 0.0228900865550381 0.1016481811051282 0.0285240963328225 0.0042460338898449 1.8437973987366657e-05 +Phosphatidic acid metabolic process 3 5 2.27173925510253 0.0231022637175843 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.2931808389803924 0.1155957163384056 0.2202973788945578 0.1283849415189241 0.0351238878380088 +Calcium ion import 5 11 2.268003511682726 0.0233289926406834 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.001383488860649 0.1604648724397155 0.0051311282902344 0.0002252796239266 0.0017617577033715 +Ether biosynthetic process 2 5 2.267293604542337 0.0233722959004765 2.279126213592233 4.927184466019417 0.4312886834031472 0.4962399070037939 1.3837655160783582 0.5481999094578265 0.9002858560873801 0.3118323573140075 0.1248399455976769 1.0 1.0 0.2159896916124382 0.0105668672564949 +Aerobic respiration 20 78 2.261600963274053 0.0237220684498205 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 0.0002545700653152 0.0065027336576065 0.0007797311297257 0.0004442680711859 2.6998527597199017e-05 +Response to l glutamate 1 5 2.244973802200426 0.0247698144252244 1.029126213592233 4.37378640776699 1.2967513270419406 0.258405010407401 0.7465949978845596 0.5879801140961596 0.7687098467942305 0.2572187080379352 0.0058945182768218 1.0 0.0824659877424542 0.018519525655472 0.0675218785318175 +Heparan sulfate proteoglycan metabolic process 1 5 2.2449461028414293 0.0247715927918648 1.766990291262136 5.121359223300971 0.5642898647972117 0.4173053251695717 1.1613006057834978 1.389918659730618 1.0230121456430192 0.3027926697750463 1.0 1.0 1.0 1.0 0.3080842130268088 +Heparan sulfate proteoglycan biosynthetic process 1 5 2.2449461028414293 0.0247715927918648 1.7160194174757282 5.026699029126213 0.5645930836787868 0.419729099473023 1.1572631253827 1.3516497566885952 1.0187409340025655 0.3042431327777389 1.0 1.0 1.0 1.0 0.2348875720984273 +Proteoglycan biosynthetic process 1 5 2.2449461028414293 0.0247715927918648 2.6432038834951457 6.677184466019417 0.8965384350791714 0.2873226841395866 1.6239641738792057 1.992745053805788 1.1569297556833695 0.2755887487741971 1.0 1.0 1.0 1.0 0.5122684088981724 +Protein transmembrane import into intracellular organelle 5 12 2.23208844397013 0.0256091180463793 4.951456310679611 13.45631067961165 1.503963012554726 0.1758225015375162 2.735521961789203 1.4944992929031071 1.2360761671845495 0.245991671368161 0.0070972540024064 0.0086801325315587 0.0028129637769054 6.623444919887721e-05 0.0027845492980534 +Embryonic brain development 1 5 2.2206613710447525 0.026373905683956 2.0776699029126213 5.808252427184466 0.2082893655462703 0.5907884890214666 1.5776923075332223 0.8358646789542162 0.7882499395935315 0.2926913643556508 0.1703279603954981 1.0 0.1253337423142017 0.2887519731811417 0.1457988469723397 +Amyloid beta formation 2 8 2.2177599344968937 0.0265712052706141 3.4466019417475726 11.150485436893204 0.7369482521385301 0.3719348072839057 1.602353580483856 1.6769930201386472 1.043709172018907 0.2948415726419107 0.0100668052313682 0.0110614955842043 0.0040337600577914 0.0474710620888575 0.0807266025333323 +Inorganic anion transmembrane transport 3 7 2.214361641563848 0.0268039113806513 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0559891440928278 0.1280604643503683 0.0307863463383066 0.0316151554384263 0.0498364179528963 +Regulation of toll like receptor signaling pathway 1 8 2.19885617867266 0.0278881503939487 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 0.1064120376614914 0.0165768393094286 0.0603249601752956 0.2676442975527425 0.6118727801456982 +Prostate gland development 1 6 2.1970486475041917 0.0280169720532263 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.3388733146593771 1.0 1.0 0.5300461112646178 0.4482773855235765 +Anion transmembrane transport 18 38 2.195127683943127 0.0281544398677022 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 0.0001148537248898 0.0018506188949832 9.101916222152158e-05 0.0003528406397473 1.6129202922500524e-06 +Nucleotide transmembrane transport 1 6 2.1672260240968937 0.0302176239693465 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0184946027378239 0.0727733471903131 0.0098557770733155 0.0553069748090555 0.0397387250697101 +Regulation of oxidative phosphorylation 0 5 2.143709806531616 0.032056145957283 2.0266990291262137 8.405339805825243 0.5212596953879275 0.3786062166885635 1.6210885042287937 1.4888813260225289 1.142050430358633 0.295953719868097 0.1921839078428937 0.0727733471903131 0.1419203898220533 0.3225700131084155 0.5492603500015365 +Intracellular protein transport 63 291 2.131325445638384 0.0330623401746867 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 0.0696985219702995 0.0138463598347011 0.0052236373578226 0.0020579014087447 2.026169279359473e-05 +Negative regulation of amyloid precursor protein catabolic process 1 7 2.123883078622168 0.0336799216866228 2.645631067961165 8.78883495145631 0.7296788020743029 0.3749260712143212 1.4314957008524525 1.1001198531094605 1.057374600950545 0.3066940057573566 0.0207808863220497 0.0028214739728005 0.0111011801010317 0.0617128865328283 0.0465653262864464 +Amyloid precursor protein catabolic process 3 13 2.099946261137555 0.0357335686492086 4.62621359223301 16.47087378640777 1.203006467000838 0.2754962460876 2.1329801006381106 2.1803683249886516 0.947433834000198 0.2709877848980267 0.0026477667531553 0.0011325878612279 0.0007806859566535 0.02082153573846 0.0187017730028202 +Mitochondrial electron transport ubiquinol to cytochrome c 2 5 2.094808493872385 0.0361880197568105 1.5048543689320388 4.206310679611651 0.8658650693935839 0.2665349265497743 0.9514810775456936 0.7935779738409815 1.3072925004771625 0.2886561243868636 0.0058945182768218 1.0 0.0824659877424542 0.0010341818226167 0.0076703518288617 +Lipophagy 2 5 2.086783835464221 0.0369076789616367 1.7451456310679612 4.766990291262136 0.2177000001101043 0.5599395204867244 1.3655258698104875 0.4664237727947306 0.8255666981734041 0.3051358138683513 0.0768774564217346 0.0279227766388577 0.0557540441617295 0.0080925194523707 0.0020376306093415 +Positive regulation of glucose import 3 5 2.0572569706097537 0.0396615140508096 1.5533980582524272 4.643203883495145 0.3596176533471029 0.4856975847415271 1.101439088125439 1.2272700097688862 0.9775890060329886 0.3007705393502626 1.0 1.0 1.0 0.3703176202019055 0.0618109910728358 +Positive regulation of glucose transmembrane transport 3 5 2.0572569706097537 0.0396615140508096 1.7111650485436891 5.388349514563107 0.2279507932540534 0.4992874334544594 1.1539596676255852 1.4054886149562396 0.971817002394224 0.2991132937072021 1.0 1.0 1.0 0.4147125777305785 0.088385561156941 +Negative regulation of multicellular organismal process 23 94 2.052655443738588 0.0401060062209983 18.75728155339806 105.0873786407767 -0.2928772776162281 0.6614464056408763 7.687735812996985 12.497849753788916 0.7546000625094377 0.3272041972626839 0.4086095891938924 0.644300944549216 0.643120509591608 0.6730406210527211 0.8003376510278422 +Sulfur compound transport 2 8 2.048183473387477 0.0405420251790735 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0092669436222975 0.1444128696349771 0.0037031463805551 0.0440381918347023 0.07392944267488 +L alpha amino acid transmembrane transport 4 11 2.047431833147644 0.0406157034876355 4.480582524271845 10.533980582524272 0.7590361902351016 0.3223730555033793 2.606398335255894 1.1951807271273862 1.273814103695318 0.3116596719827348 0.3563182260625978 1.0 0.2709026461704186 0.1876112798662428 0.0203628052401783 +Protein transmembrane transport 9 21 2.045989074265562 0.0407574456335717 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0006511757732204 0.0019447965050573 0.0001404709982685 4.061824500192176e-06 6.470525843091244e-06 +Mitochondrial transmembrane transport 21 45 2.0404838296995367 0.0413021599850578 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 1.3486103848593806e-08 2.604053999318058e-06 1.3213559978348707e-06 1.3610535960463702e-10 5.718781720245928e-11 +Lipoprotein localization 3 7 2.02246659356937 0.0431281714025528 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.0004576058289099 0.0550816697898294 0.0055563644779973 0.0001383364889708 0.0019884945269669 +Cerebellar cortex formation 2 6 2.021859333872775 0.0431908859667617 1.6553398058252426 5.220873786407767 0.2521110595791076 0.5027949697945344 1.5288950356918125 1.0414940787680762 0.9282578099105055 0.2889735945613402 1.0 1.0 1.0 0.0491545726752397 0.0334620993119388 +Endoplasmic reticulum tubular network organization 1 8 2.0199783310381063 0.0433856352442192 4.150485436893204 10.555825242718448 0.8961707031484618 0.3171343629503343 2.1669796342432037 1.8339543060404635 1.2935176897309475 0.3199619326088047 0.0207808863220497 0.0028214739728005 0.0111011801010317 0.0617128865328283 0.0078812527225172 +Vitamin transmembrane transport 3 5 2.017673783828504 0.0436252468973099 2.9344660194174756 6.094660194174757 1.6910321805591797 0.1136175735100163 1.344920850275403 0.8913122381585616 1.0580472895861666 0.1862049292817703 0.1813283262685859 0.0683810764565047 0.1336663515258769 0.3058660732099017 0.0334620993119388 +Purine containing compound transmembrane transport 2 5 2.01287575508829 0.0441277017643328 3.6432038834951457 8.228155339805825 0.8480777288434221 0.3004167480224937 2.0847056152178514 1.431742605530374 1.2278207398320582 0.2967021731271802 0.1703279603954981 1.0 0.1253337423142017 0.2887519731811417 0.1457988469723397 +Nucleotide transport 3 9 2.01219309292714 0.0441995863172379 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.0459772463951516 0.1155957163384056 0.0251008323038497 0.1283849415189241 0.0351238878380088 +Regulation of mitochondrial gene expression 1 9 2.0111160477034087 0.0443132005067568 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 0.0492344028755968 0.0070670490819082 0.0269433955752302 0.1365592686609386 0.3798345415961738 +L amino acid transport 4 12 2.009900652129253 0.0444417047339551 5.114077669902913 11.91504854368932 0.7755289387861473 0.3283794523692901 2.998235059113201 1.3256494094845783 1.3058948249973923 0.3189923022900864 0.3648685595715168 1.0 0.277861461810767 0.1963700434786238 0.0229507437408614 +Response to endoplasmic reticulum stress 26 73 1.9965220299199349 0.045877130280604 20.766990291262136 81.87135922330097 0.3895578367391949 0.6272162805638101 7.658618957730667 6.11384352257493 0.925049322897134 0.3624458148773257 0.7468644857856499 1.0 0.2965849437799202 0.0225483019498731 3.682848707849801e-05 +Antigen processing and presentation of endogenous antigen 4 6 1.995812335041218 0.0459543536504294 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 1.0 1.0 1.0 0.3058660732099017 0.0048822579474643 +Antigen processing and presentation of endogenous peptide antigen 4 6 1.995812335041218 0.0459543536504294 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 1.0 1.0 1.0 0.2887519731811417 0.003721367796782 +Mitochondrial calcium ion transmembrane transport 2 7 1.9942705158054208 0.046122499561058 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.001120485924295 0.0727733471903131 0.0098557770733155 0.0060877577335729 0.0062633876942655 +Metal ion transport 19 90 1.99285929726394 0.0462768564218989 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.1784767388061347 0.4913390105790043 0.2364961234198578 0.2162923061857961 0.247832396276347 +Positive regulation of erbb signaling pathway 0 5 1.986064746621762 0.0470261350860334 1.5 5.803398058252427 0.1697330179396052 0.559951300945358 1.3679763241010316 1.2356705293417043 0.8062713301941858 0.2749583692357806 0.2134682598557817 0.0814971443263516 0.1581956798045988 0.3547863423381785 0.5920308942141137 +Mitochondrial respiratory chain complex assembly 12 30 1.9759032863738792 0.0481657319236696 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 2.5902409586595547e-05 0.0089029299634258 0.0017133517402868 1.069692559312704e-05 2.8683931545955265e-05 +Endoplasmic reticulum membrane organization 3 7 1.9719517520315613 0.0486151146086444 3.5679611650485437 8.12621359223301 0.656874598832497 0.271683145803182 1.813579499342004 1.2879547393790816 1.532817064292788 0.2945772195616556 0.0123366773007521 0.0595353304203936 0.0065261066260236 0.0376759114543004 0.0027630263410089 +Bergmann glial cell differentiation 3 5 1.9669716908804635 0.049186474523799 1.4635922330097086 4.883495145631068 0.2432230701216105 0.5985855589785339 1.362156595626081 0.8623851647068913 0.8032194403691936 0.2972106684584192 1.0 1.0 1.0 0.0004465916791071 0.0001708540892308 +Intracellular protein transmembrane transport 8 18 1.9635849550183724 0.0495782435455698 7.233009708737864 21.9004854368932 1.450039081018812 0.2247265328975946 3.8281123729210935 2.4627910122818513 1.3220665029303609 0.2876555154826584 0.0028766502725946 0.018891152845815 0.000850654769639 8.835116681609278e-05 0.0002580266226921 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..81495b1bb90fc7e50f10b401d50096f7ecbe8434 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 6337, + "title": "Average number of proteins per term", + "value": 17.34448477197412 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6a03d71217e33bc13241aea6c5320fb3cf2ca948 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..06d527ddd37f5bacf503df470f9121006cb7b0f2 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,1636 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.6093404254563732 5.306030119263454 1.1203845305850289e-07 0.0007097357351701 0.000709987677038 187 Q99595,Q9NS69,O60830,Q70HW3,Q14728,P13073,P12235,Q8IYU8,Q01650,Q96ES6,P62942,P21796,Q9HD20,Q8NEW0,O43865,P23786,Q9UHG3,Q9Y619,Q15041,P45880,Q9H2D1,P56134,P20020,O75964,P00403,Q9Y4W6,P24539,O95831,P52789,P06576,Q13423,P38435,P30825,Q9BPX6,Q9UBX3,Q9BZF1,P53985,Q15388,P47985,P16615,Q7KZN9,Q06124,Q8IXU6,O14925,Q8NE01,Q9HC21,P42858,Q9UGP8,Q9UDW1,Q4KMQ2,Q8TB61,Q15629,Q8NHS3,Q9UJS0,O75844,Q07820,O43772,Q5SR56,Q9Y4C2,Q00325,Q3ZCQ8,Q96PU5,Q96GC9,P31751,Q6P4A7,Q9Y277 66 +Mitochondrion organization 0.5656336471777265 4.594323466263173 4.3415548589553765e-06 0.0271374713624534 0.0107536148746165 155 Q99595,Q9NS69,O60830,O75880,O43676,O43819,P21796,P03886,Q8N4H5,P45880,P14406,P30536,Q8N2A8,Q9Y2R0,P55786,Q5TC12,O95831,O60313,Q15070,Q15388,P47985,Q13505,O14925,Q96A26,P42858,O96000,O75153,Q9Y6M9,Q9BQP7,Q9H061,Q5JRX3,Q3ZCQ8,Q96CU9,Q9BUK6,Q9Y6C9,Q6DKK2 36 +Ion transmembrane transport 0.5803623392148738 4.561007748129047 5.090870226265309e-06 0.0317460942214488 0.0107536148746165 138 P13073,Q14728,Q70HW3,P12235,Q8IYU8,Q01650,Q96ES6,P62942,P21796,Q9HD20,Q8NEW0,O43865,Q9UHG3,Q9Y619,Q15041,P45880,Q9H2D1,P56134,P20020,O75964,P00403,P24539,Q13423,P30825,Q9BPX6,Q9UBX3,P53985,Q7KZN9,P47985,P16615,Q9HC21,P42858,Q9UDW1,Q4KMQ2,Q8TB61,Q9UJS0,O75844,O43772,Q9Y4C2,Q00325,Q96PU5,Q96GC9,Q6P4A7,Q9Y277 44 +Ion transport 0.51896336064274 4.1527990482259405 3.284331325725809e-05 0.1878997566136879 0.0520320190278127 187 P13073,Q14728,Q70HW3,P04083,P12235,Q8IYU8,Q9NZJ7,Q01650,Q96ES6,P62942,P21796,Q9HD20,Q8NEW0,O43865,O76024,Q9UHG3,Q9Y619,Q15041,P45880,Q9H2D1,P56134,P20020,P30536,O75964,P00403,Q9Y4W6,Q15042,P24539,O15173,Q13423,P30825,Q9BPX6,Q9UBX3,P53985,Q13555,Q7KZN9,P47985,P16615,Q8NE01,Q9HC21,P42858,O14936,Q9UDW1,Q4KMQ2,Q8TB61,Q9UJS0,O75844,P51809,O43772,Q9Y4C2,Q00325,Q96PU5,Q96GC9,Q6P4A7,Q9Y277 55 +Cation transport 0.4958815779278688 3.572389556137985 0.000353738683561 0.8937583018195459 0.1603769123659739 140 P13073,P12235,Q70HW3,Q8IYU8,Q96ES6,P62942,P21796,Q9HD20,Q8NEW0,O43865,O76024,Q9Y619,P56134,P20020,P30536,O75964,P00403,Q9Y4W6,P24539,O15173,Q13423,P30825,Q9BPX6,Q13555,Q7KZN9,P47985,P16615,Q9HC21,P42858,O14936,Q9UDW1,Q4KMQ2,O75844,P51809,O43772,Q00325,Q96PU5,Q96GC9,Q01650 39 +Cation transmembrane transport 0.5278499350619967 3.538882287901665 0.0004018249903452 0.9216740800911228 0.1603769123659739 107 P13073,P12235,Q70HW3,Q8IYU8,Q96ES6,P62942,P21796,Q9HD20,Q8NEW0,Q9Y619,P56134,P20020,O75964,P00403,Q9Y4W6,P24539,Q13423,P30825,Q9BPX6,Q7KZN9,P47985,P16615,Q9HC21,P42858,Q9UDW1,Q4KMQ2,O43772,Q00325,Q96PU5,Q96GC9,Q01650 31 +Protein targeting 0.5111386476652867 3.2748142388286037 0.001057314740136 0.9987736930661668 0.1603769123659739 99 Q99595,Q9NS69,O60830,O60725,Q8N4H5,P43307,Q15041,P30536,P55786,O95831,Q15388,O14925,Q9Y5M8,Q9UGP8,Q15005,P40855,Q15629,P46379,Q8TB36,Q9Y4C2,Q5JRX3,Q3ZCQ8,P31751,Q9Y2T2 24 +Inorganic ion transmembrane transport 0.4977771356214737 3.118478992380004 0.0018178710079068 0.9999901725599856 0.1603769123659739 98 P13073,P12235,Q8IYU8,Q96ES6,P62942,P21796,Q9HD20,Q9UHG3,P56134,P20020,O75964,P00403,Q9Y4W6,P24539,Q13423,Q9BPX6,Q9UBX3,Q7KZN9,P47985,P16615,P42858,Q9UDW1,Q4KMQ2,Q00325,Q96PU5,Q96GC9 26 +Mitochondrial transport 0.5850736409737487 2.925167548656282 0.0034427080844476 0.99999999967723 0.1603769123659739 77 Q99595,Q9NS69,O60830,P12235,Q8N4H5,P23786,P45880,P56134,P30536,O75964,P55786,P24539,Q9P0J0,O95831,P52789,Q9UBX3,Q15070,Q15388,O14925,Q9UJS0,O43772,Q8TB36,Q5JRX3,Q3ZCQ8 24 +Dna methylation involved in gamete generation 0.9498220640569432 2.7830893443027245 0.0053843976581429 0.9999999999999988 0.1603769123659739 2 Q8N2A8 1 +Ornithine transport 0.9469750889679748 2.771584557913021 0.0055784181609248 0.9999999999999996 0.1603769123659739 2 P30825 1 +Phosphatidylcholine acyl chain remodeling 0.939501779359434 2.7413059286439014 0.0061195499828414 1.0 0.1603769123659739 2 Q96N66 1 +Cellular respiration 0.4668723882273566 2.7314455647582405 0.0063057156886041 1.0 0.1603769123659739 91 P13073,O43676,O43819,P36404,P03886,P14406,O75964,P00403,P24539,Q13423,Q15070,Q7KZN9,P47985,O75874,O96000,Q9UDW1,Q9UJS0,Q9Y6M9,O14949,O75306,P48735 21 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.9359430604982236 2.726847409449943 0.0063942601253443 1.0 0.1603769123659739 2 O75844 1 +Mitochondrial proton transporting atp synthase complex assembly 0.9330960854092524 2.7152618954331107 0.0066223377562322 1.0 0.1603769123659739 2 Q5TC12 1 +Calcium ion import into sarcoplasmic reticulum 0.9309608540925304 2.7065618311523183 0.0067983921140737 1.0 0.1603769123659739 2 O75844 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.9312922748309022 2.7052571325033323 0.0068251535904995 1.0 0.1603769123659739 3 Q96GC9,O43865 2 +Prenylation 0.9262329059183336 2.6845128651103245 0.0072635587775033 1.0 0.1603769123659739 3 Q92696 1 +Autophagosome membrane docking 0.918640516068096 2.653283100320677 0.007971298316405 1.0 0.1603769123659739 3 Q96GC9 1 +T cell tolerance induction 0.9128113879003584 2.632231155024774 0.0084826127730466 1.0 0.1603769123659739 2 P01889 1 +Lymphocyte anergy 0.9128113879003584 2.632231155024774 0.0084826127730466 1.0 0.1603769123659739 2 P01889 1 +Negative regulation of lipid transport 0.9113879003558708 2.626372399061437 0.0086300342617637 1.0 0.1603769123659739 2 Q06124 1 +Regulation of response to food 0.908185053380789 2.613174759101276 0.008970541947473 1.0 0.1629674508536708 2 P80303 1 +Negative regulation of response to food 0.908185053380789 2.613174759101276 0.008970541947473 1.0 0.1629674508536708 2 P80303 1 +Regulation of appetite 0.908185053380789 2.613174759101276 0.008970541947473 1.0 0.1629674508536708 2 P80303 1 +Fatty acid elongation 0.9078291814946632 2.6117070338328077 0.009009142033157 1.0 0.1629674508536708 2 Q9NZ01 1 +Negative regulation of glial cell proliferation 0.8985765124555216 2.5734532355379085 0.0100689253091537 1.0 0.1666697939010463 2 Q96G23 1 +Regulation of lipophagy 0.8930137192737713 2.5469822167703127 0.0108658970277344 1.0 0.1695304978844624 3 O15269 1 +Positive regulation of mitochondrial translation 0.8886595272093758 2.5233304915235393 0.0116249090420104 1.0 0.1720607735488639 5 Q567V2 1 +Azole transmembrane transport 0.8832740213523226 2.509792841077282 0.0120802006294991 1.0 0.1720607735488639 2 P30825 1 +Quaternary ammonium group transport 0.8832740213523209 2.5097928410772754 0.0120802006294993 1.0 0.1720607735488639 2 O43772 1 +Calcium import into the mitochondrion 0.8846989446124482 2.509144103199148 0.0121024101596596 1.0 0.1720607735488639 4 Q9BPX6,P21796 2 +Response to light intensity 0.8822064056939489 2.505332994755315 0.0122336156380602 1.0 0.1720607735488639 2 P31751 1 +Negative regulation of tumor necrosis factor superfamily cytokine production 0.8830450477053966 2.505257864699681 0.0122362147679737 1.0 0.1720607735488639 3 O43823 1 +Gdp metabolic process 0.8804270462633472 2.4978945633913305 0.0124933346405686 1.0 0.1720607735488639 2 O14936 1 +Cardiac epithelial to mesenchymal transition 0.8808241243779047 2.495933384206269 0.0125626191246586 1.0 0.1720607735488639 3 Q9NQC3 1 +Purine deoxyribonucleoside triphosphate metabolic process 0.8779359430605018 2.487469507735278 0.0128655482007082 1.0 0.1720607735488639 2 Q9Y3Z3 1 +Positive regulation of mitochondrial calcium ion concentration 0.8785485293373502 2.4831971775538877 0.0130208990868234 1.0 0.1720607735488639 4 Q9BPX6 1 +Organic cation transport 0.8778582193968881 2.480279907570749 0.0131279282018599 1.0 0.1720607735488639 4 O43772,Q70HW3 2 +Regulation of mast cell activation 0.8758007117437804 2.4785232890491837 0.0131927498168065 1.0 0.1720607735488639 2 P09601 1 +Regulation of mast cell activation involved in immune response 0.8758007117437804 2.4785232890491837 0.0131927498168065 1.0 0.1720607735488639 2 P09601 1 +Growth plate cartilage development 0.8732496205514397 2.4640531917925212 0.013737572266451 1.0 0.1725915627281091 3 O75844 1 +Bone growth 0.8732496205514397 2.4640531917925212 0.013737572266451 1.0 0.1725915627281091 3 O75844 1 +Regulation of translation initiation in response to endoplasmic reticulum stress 0.8718861209964424 2.4620967924996857 0.013812738432799 1.0 0.1725915627281091 2 Q15363 1 +Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation 0.8718861209964424 2.4620967924996857 0.013812738432799 1.0 0.1725915627281091 2 Q15363 1 +Ephrin receptor signaling pathway 0.870560966636474 2.452707590549169 0.0141785542480505 1.0 0.1725915627281091 3 Q14155 1 +Phosphatidylethanolamine biosynthetic process 0.8690391459074739 2.4501298298645517 0.0142804713276201 1.0 0.1725915627281091 2 Q9Y6K0 1 +Regulation of caveolin mediated endocytosis 0.8683274021352423 2.4471354001884715 0.0143996732329971 1.0 0.1725915627281091 2 Q13432 1 +Cellular copper ion homeostasis 0.8682547025504183 2.442963320690653 0.0145672177252562 1.0 0.1725915627281091 3 O75880 1 +Copper ion homeostasis 0.8682547025504183 2.442963320690653 0.0145672177252562 1.0 0.1725915627281091 3 O75880 1 +Energy derivation by oxidation of organic compounds 0.4331599644098345 2.442371205874749 0.0145911349189622 1.0 0.1725915627281091 109 P13073,O43676,O43819,P36404,P03886,P56134,P14406,O75964,P00403,P24539,P13807,Q13423,Q15070,Q7KZN9,P47985,O75874,O96000,Q9UDW1,Q9UJS0,P46976,Q9Y6M9,O14949,O75306,P48735,P31751 25 +Positive regulation of cell migration involved in sprouting angiogenesis 0.8676847448137246 2.4405534255639196 0.0146647766333769 1.0 0.1725915627281091 3 P09601 1 +Regulation of cell migration involved in sprouting angiogenesis 0.8676847448137246 2.4405534255639196 0.0146647766333769 1.0 0.1725915627281091 3 P09601 1 +Positive regulation of endothelial cell apoptotic process 0.8676713890632893 2.440496946472053 0.0146670699465454 1.0 0.1725915627281091 3 Q53EL6 1 +Endothelial cell apoptotic process 0.8676713890632893 2.440496946472053 0.0146670699465454 1.0 0.1725915627281091 3 Q53EL6 1 +Positive regulation of mitophagy 0.8624498988497723 2.4183870145281317 0.0155894861370682 1.0 0.1725915627281091 3 P21796 1 +Nucleobase transport 0.8619967701093749 2.416465535190196 0.0156720098063187 1.0 0.1725915627281091 3 Q9Y277 1 +Forebrain regionalization 0.8608540925266976 2.4156288765611076 0.0157080625466174 1.0 0.1725915627281091 2 Q7Z4L5 1 +Negative regulation of lipase activity 0.8609631810898001 2.4120809886239485 0.0158617577003252 1.0 0.1725915627281091 3 P04083 1 +Proton transporting two sector atpase complex assembly 0.8592135840193493 2.401101236774264 0.0163458136211889 1.0 0.1725915627281091 4 Q5TC12,Q8N511 2 +Mitochondrial cytochrome c oxidase assembly 0.8595959341948695 2.399670912867466 0.0164098171746742 1.0 0.1725915627281091 5 O75880,Q9Y2R0,Q15070 3 +Peptidyl arginine methylation to asymmetrical dimethyl arginine 0.8570030746006474 2.3952608370250577 0.0166085454319484 1.0 0.1725915627281091 3 Q86X55 1 +Cytochrome complex assembly 0.858237481064774 2.392158038295956 0.0167496283667762 1.0 0.1725915627281091 8 O75880,P47985,Q9Y2R0,O43819,Q6DKK2,Q15070 6 +Positive regulation of biomineralization 0.8540925266903912 2.3870205418068706 0.0169855421741069 1.0 0.1733291155512333 2 Q4KMQ2 1 +Positive regulation of bone mineralization 0.8540925266903912 2.3870205418068706 0.0169855421741069 1.0 0.1733291155512333 2 Q4KMQ2 1 +Regulation of modification of postsynaptic structure 0.8526188708249158 2.376600237167722 0.01747301325837 1.0 0.1733951319779426 3 Q9UQB8 1 +Regulation of modification of synaptic structure 0.8526188708249158 2.376600237167722 0.01747301325837 1.0 0.1733951319779426 3 Q9UQB8 1 +Calmodulin dependent kinase signaling pathway 0.8524315568519438 2.3758020512539453 0.0175108539255939 1.0 0.1733951319779426 3 O75844 1 +Regulation of calcium ion import 0.8528866610183177 2.3740629975215226 0.0175935484505971 1.0 0.1733951319779426 4 P21796 1 +Response to food 0.8535752538380353 2.373826684457392 0.0176048118567022 1.0 0.1733951319779426 5 P80303,Q9UMX5 2 +Phosphatidylethanolamine metabolic process 0.8504805980776076 2.3674841210295647 0.0179094885412947 1.0 0.1743512416805754 3 Q9Y6K0,P35790 2 +Calcium ion regulated exocytosis of neurotransmitter 0.8483985765124636 2.3628537239506984 0.0181348258976972 1.0 0.1752992091799921 2 P16615 1 +Positive regulation of erad pathway 0.8467911019144982 2.3479320713081036 0.0188779637944389 1.0 0.1798942203990371 4 Q4ZIN3,P46379 2 +Respiratory chain complex iv assembly 0.8458022577089261 2.337507958933575 0.0194127875870182 1.0 0.1799304771004491 6 O75880,O43819,Q9Y2R0,Q15070 4 +Negative regulation of lipid localization 0.8430046279814947 2.335534757168429 0.0195155023758009 1.0 0.1799304771004491 3 P31751,Q06124 2 +Telencephalon glial cell migration 0.8446123234969981 2.332181842410732 0.0196911269774784 1.0 0.1799304771004491 7 Q9NQC3 1 +Cerebral cortex radially oriented cell migration 0.8446123234969981 2.332181842410732 0.0196911269774784 1.0 0.1799304771004491 7 Q9NQC3 1 +Aromatic amino acid transport 0.8418708376787386 2.3306789207290985 0.0197702965098971 1.0 0.1799304771004491 3 P30825 1 +Cellular response to increased oxygen levels 0.8442247765910302 2.330664603586911 0.0197710520297571 1.0 0.1799304771004491 6 Q8N511 1 +Protein import into mitochondrial matrix 0.8432666573660965 2.3277312677574495 0.0199263777425282 1.0 0.1799304771004491 9 Q99595,Q15388,O60830,O14925 4 +Detection of other organism 0.8391459074733197 2.3234350785777744 0.0201557914970051 1.0 0.1803418758778243 2 P01889 1 +Negative regulation of natural killer cell mediated immunity 0.8391459074733197 2.3234350785777744 0.0201557914970051 1.0 0.1803418758778243 2 P01889 1 +Protection from natural killer cell mediated cytotoxicity 0.8391459074733197 2.3234350785777744 0.0201557914970051 1.0 0.1803418758778243 2 P01889 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.8394446422214354 2.3202786677099696 0.0203258073456831 1.0 0.1803418758778243 3 P01889,P10321 2 +Fatty acid beta oxidation using acyl coa oxidase 0.8402351668998244 2.319738310089714 0.020355038064965 1.0 0.1803418758778243 4 O15254 1 +Anion transport 0.6401597319519213 2.3164816089396463 0.0205319874502474 1.0 0.1803418758778243 62 Q14728,P12235,P04083,Q9NZJ7,Q01650,P21796,O43865,Q9UHG3,Q9Y619,Q15041,P45880,Q9H2D1,P30536,P30825,Q9UBX3,P53985,Q9HC21,Q4KMQ2,Q8TB61,Q9UJS0,Q9Y4C2,Q00325,Q9Y277 23 +Regulation of mitophagy 0.840024722551335 2.3153734365027465 0.0205925039595926 1.0 0.1803418758778243 5 P21796 1 +Respiratory chain complex iii assembly 0.8380974062313351 2.3144980872605947 0.0206404160526068 1.0 0.1803418758778243 3 Q6DKK2 1 +Membrane organization 0.3890337462960219 2.313520292872754 0.020694050362086 1.0 0.1803418758778243 207 Q9NS69,P50402,P04083,P12235,Q9NZJ7,Q9NQC3,O14964,Q9UQB8,Q9NX63,O60343,O15118,P57088,Q15041,Q86XL3,P45880,Q15392,O43765,P30536,O15228,Q9ULX6,Q9H3K2,P53992,Q5JRA6,Q9Y4W6,O00429,Q53EZ4,O15258,P42356,Q9P0J0,P52789,Q9P2W9,Q9BZF1,O60313,Q15070,P49755,P16615,Q13505,Q13190,Q96S97,Q96A33,O43760,Q4KMQ2,Q15629,Q8NCW5,Q8N1F7,Q6UXV4,O75844,P46379,P51809,Q15363,Q9HCU5,Q9BVK6,O15027,Q3ZCQ8,P55735,Q8NFQ8,Q53H12,Q96GC9,O14976,P31751,Q9Y512,Q9NPA0 62 +Phosphate ion transport 0.8357119582905126 2.304253308410716 0.0212084283190672 1.0 0.1823771844671884 3 Q9UBX3 1 +Phosphate ion transmembrane transport 0.8357119582905126 2.304253308410716 0.0212084283190672 1.0 0.1823771844671884 3 Q9UBX3 1 +Positive regulation of vesicle fusion 0.8352362915971726 2.3022090044488426 0.0213233884253853 1.0 0.1830979843518526 3 P04083 1 +Chloride transmembrane transport 0.8331148476973642 2.289012582965032 0.0220786212985977 1.0 0.1886009922438639 4 Q9UHG3 1 +Angiotensin activated signaling pathway 0.8319828962146427 2.288213666830628 0.0221250812053082 1.0 0.1887034180323527 3 O43865 1 +Cellular response to ether 0.8302491103202859 2.2853601245028576 0.0222917201314418 1.0 0.1889016706738656 2 P11802 1 +Response to ether 0.8305446778212903 2.282019557789915 0.0224881856048777 1.0 0.1889016706738656 3 P11802,Q14103 2 +Positive regulation of collagen metabolic process 0.828825622775812 2.279252444051045 0.0226520632016162 1.0 0.1889016706738656 2 P08670 1 +Positive regulation of fatty acid biosynthetic process 0.8284697508896918 2.277724847828696 0.0227429763359148 1.0 0.1889016706738656 2 P04083 1 +Phosphatidylglycerol acyl chain remodeling 0.8284697508896904 2.2777248478286887 0.0227429763359152 1.0 0.1889016706738656 2 Q8NF37 1 +Peptidyl arginine n methylation 0.8299626274656255 2.2753752069011544 0.0228834313698858 1.0 0.1889016706738656 4 Q86X55 1 +Peptidyl arginine methylation 0.8299626274656255 2.2753752069011544 0.0228834313698858 1.0 0.1889016706738656 4 Q86X55 1 +Positive regulation of fatty acid metabolic process 0.8287646849412673 2.274347356461447 0.0229451099589843 1.0 0.1889016706738656 3 P31751,P04083 2 +Phosphatidic acid metabolic process 0.829969023419199 2.27173925510253 0.0231022637175843 1.0 0.1889016706738656 5 Q9NPH0,Q8NF37,Q99943 3 +Endocrine process 0.8270462633452057 2.2716117587090134 0.0231099700464656 1.0 0.1889016706738656 2 Q06124 1 +Regulation of vasoconstriction 0.8270462633451956 2.2716117587089695 0.0231099700464683 1.0 0.1889016706738656 2 P20020 1 +Negative regulation of nik nf kappab signaling 0.8288280951306505 2.270461671812708 0.0231795862796788 1.0 0.1889016706738656 4 Q99829,O43657 2 +Calcium ion import 0.8290494066328458 2.268003511682726 0.0233289926406834 1.0 0.1889016706738656 11 P16615,Q8IYU8,P21796,Q9BPX6,O75844 5 +Ether biosynthetic process 0.8289473226425215 2.2672936045423375 0.0233722959004765 1.0 0.1889016706738656 5 P49327,O00116 2 +Aerobic respiration 0.5034595083357735 2.2616009632740535 0.0237220684498205 1.0 0.1900464573533659 78 P13073,O43676,P36404,P03886,P56134,P14406,O75964,P00403,P24539,Q13423,Q15070,Q7KZN9,P47985,O75874,O96000,Q9UDW1,Q9Y6M9,O14949,O75306,P48735 20 +Regulation of chondrocyte differentiation 0.8255728136495183 2.2563480280359283 0.0240488437472707 1.0 0.1916949972659811 4 P16435,Q06124 2 +Regulation of cartilage development 0.8255728136495183 2.2563480280359283 0.0240488437472707 1.0 0.1916949972659811 4 P16435,Q06124 2 +Response to l glutamate 0.8238255930157867 2.244973802200426 0.0247698144252244 1.0 0.1950032093441581 5 O95831 1 +Heparan sulfate proteoglycan metabolic process 0.8238192449079729 2.2449461028414293 0.0247715927918648 1.0 0.1950032093441581 5 Q99805 1 +Heparan sulfate proteoglycan biosynthetic process 0.8238192449079729 2.2449461028414293 0.0247715927918648 1.0 0.1950032093441581 5 Q99805 1 +Proteoglycan biosynthetic process 0.8238192449079729 2.2449461028414293 0.0247715927918648 1.0 0.1950032093441581 5 Q99805 1 +Protein transmembrane import into intracellular organelle 0.8205494789421331 2.23208844397013 0.0256091180463793 1.0 0.1983923973837479 12 Q99595,Q15388,O60830,O14925,O95831 5 +Humoral immune response mediated by circulating immunoglobulin 0.8167259786477008 2.2271625239982034 0.0259364137633408 1.0 0.1993382199469532 2 Q9UQ84 1 +Mda 5 signaling pathway 0.816725978647689 2.22716252399815 0.0259364137633444 1.0 0.1993382199469532 2 O75179 1 +Regulation of mda 5 signaling pathway 0.816725978647689 2.22716252399815 0.0259364137633444 1.0 0.1993382199469532 2 O75179 1 +Alpha beta t cell proliferation 0.8168622648213195 2.2228705700971796 0.02622452876892 1.0 0.2004491273221313 3 Q96J02 1 +Positive regulation of receptor catabolic process 0.8153024911032127 2.2210137674068515 0.0263500289267466 1.0 0.2004491273221313 2 Q96J02 1 +Embryonic brain development 0.8182613488831108 2.2206613710447525 0.026373905683956 1.0 0.2004491273221313 5 Q9BVA1 1 +Motor neuron apoptotic process 0.8157181732586887 2.2179065095112995 0.02656120758236 1.0 0.201411124515344 3 P49327 1 +Amyloid beta formation 0.8185874010559968 2.2177599344968937 0.0265712052706141 1.0 0.201411124515344 8 Q9NQC3,O95197 2 +Inorganic anion transmembrane transport 0.8177805851896834 2.214361641563848 0.0268039113806513 1.0 0.2026925852257605 7 Q9UHG3,Q9UBX3,Q00325 3 +Protein transport along microtubule 0.8127447490210091 2.20499212824229 0.0274546469156018 1.0 0.2045518702257307 3 Q14168,P04792 2 +Protein localization to presynapse 0.8127447490210091 2.20499212824229 0.0274546469156018 1.0 0.2045518702257307 3 Q14168,P04792 2 +Axo dendritic protein transport 0.8127447490210091 2.20499212824229 0.0274546469156018 1.0 0.2045518702257307 3 Q14168,P04792 2 +Positive regulation of ire1 mediated unfolded protein response 0.811387900355874 2.204082426700276 0.0275185477900854 1.0 0.2045518702257307 2 P18031 1 +Positive regulation of endoplasmic reticulum unfolded protein response 0.811387900355874 2.204082426700276 0.0275185477900854 1.0 0.2045518702257307 2 P18031 1 +Regulation of perk mediated unfolded protein response 0.811387900355874 2.204082426700276 0.0275185477900854 1.0 0.2045518702257307 2 P18031 1 +Regulation of toll like receptor signaling pathway 0.8143361858012912 2.19885617867266 0.0278881503939487 1.0 0.2045518702257307 8 Q9NQC3 1 +Prostate gland development 0.8136703664850833 2.1970486475041913 0.0280169720532263 1.0 0.2045518702257307 6 P04083 1 +Anion transmembrane transport 0.7540732197003672 2.195127683943127 0.0281544398677022 1.0 0.2049924973255456 38 P12235,Q14728,P30825,Q01650,Q9HC21,Q9Y4C2,P21796,Q9UJS0,Q00325,Q9Y277,Q4KMQ2,Q9UHG3,Q9Y619,Q8TB61,P45880,Q9H2D1,Q9UBX3,P53985 18 +Negative regulation of hormone metabolic process 0.8092526690391444 2.194833398470944 0.0281755507606991 1.0 0.2049924973255456 2 O60678 1 +Response to auditory stimulus 0.805338078291827 2.177851661783628 0.0294170822525521 1.0 0.2086613050802621 2 P42858 1 +Phosphatidylserine metabolic process 0.8056247775008947 2.1739914251199264 0.0297057791837687 1.0 0.2098612293060672 3 Q9BZF1,Q8NCC3 2 +Intracellular distribution of mitochondria 0.8035587188612259 2.170121926244742 0.0299976105590802 1.0 0.210514793037532 2 O75153 1 +Nucleotide transmembrane transport 0.8069132150406617 2.1672260240968937 0.0302176239693465 1.0 0.2108888370556647 6 Q9H2D1 1 +Maintenance of protein localization in endoplasmic reticulum 0.8024911032028598 2.165480858457097 0.0303508797244513 1.0 0.2108888370556647 2 O43292 1 +Protein retention in er lumen 0.8024911032028598 2.165480858457097 0.0303508797244513 1.0 0.2108888370556647 2 O43292 1 +Inflammatory cell apoptotic process 0.8043107523150357 2.163603921864204 0.0304947602920588 1.0 0.2108888370556647 4 O75844 1 +Negative regulation of leukocyte mediated immunity 0.8041293062375141 2.162808292363607 0.0305559275496367 1.0 0.2108888370556647 4 P01889,P09601 2 +Er overload response 0.80341426112655 2.1596721798809524 0.0307980563267895 1.0 0.2108888370556647 4 O76024,Q96A33 2 +Modified amino acid transport 0.8026704031549663 2.1564085375564783 0.0310517786120148 1.0 0.2108888370556647 4 Q9H2D1 1 +Positive regulation of heart rate 0.797153024911045 2.142239265001145 0.0321742333587369 1.0 0.2113776353854033 2 P16615 1 +Actin myosin filament sliding 0.79743681025276 2.138207055416029 0.0324999420100278 1.0 0.2113776353854033 3 P60660,P14649 2 +Positive regulation of blood circulation 0.79743681025276 2.138207055416029 0.0324999420100278 1.0 0.2113776353854033 3 P05023,P16615 2 +Regulation of phospholipid catabolic process 0.7953736654804329 2.1344786570469494 0.0328036189201814 1.0 0.2113776353854033 2 O75874 1 +Positive regulation of nitric oxide synthase activity 0.7953736654804298 2.134478657046936 0.0328036189201825 1.0 0.2113776353854033 2 P00374 1 +Phosphatidylcholine catabolic process 0.7953736654804255 2.134478657046917 0.0328036189201841 1.0 0.2113776353854033 2 Q8NCC3 1 +Intracellular protein transport 0.3530613052184116 2.131325445638384 0.0330623401746867 1.0 0.2118463596430639 291 Q99595,Q9NS69,O60830,P50402,O60725,P18031,O14964,Q9UKG1,O43865,Q8N4H5,P43307,Q15041,Q9BUN8,O43765,P30536,Q9Y678,Q9Y282,P53992,P55786,Q9BW83,Q9P0J0,O95831,Q9P2W9,Q96CS3,Q9Y5X3,P04792,O15260,Q15070,P49755,Q15388,Q06124,O14925,Q9Y5M8,Q13190,Q9Y3A6,Q9UGP8,Q96L92,Q14168,Q15005,O75312,P40855,Q15629,Q8TCT9,Q8N1F7,Q7Z4Q2,P46379,Q9HCU5,Q15363,Q9BVK6,O15027,Q8TB36,Q9Y4C2,Q9GZP9,Q5JRX3,Q9Y679,Q3ZCQ8,P55735,O95376,Q53H12,Q9Y3B3,P31751,Q9Y512,Q9Y2T2 63 +Plasma membrane phospholipid scrambling 0.7956620929526084 2.130432108597134 0.0331359553005587 1.0 0.2119017505621445 3 Q96GC9 1 +Detection of external biotic stimulus 0.7956568173727402 2.1304089865848783 0.033137862522816 1.0 0.2119017505621445 3 P01889,P04439 2 +Detection of biotic stimulus 0.7959401709401631 2.126826275201185 0.03343452029406 1.0 0.2133681320276519 4 P01889,P04439,P30536 3 +Peripheral nervous system axon regeneration 0.7945735088841983 2.1256597703643676 0.0335315989357305 1.0 0.2135575301062557 3 Q96G23 1 +Negative regulation of amyloid precursor protein catabolic process 0.7974140267903076 2.123883078622168 0.0336799216866228 1.0 0.213774162792679 7 Q9NQC3 1 +Positive regulation of calcium ion import 0.7893238434163835 2.1080425541654275 0.0350273087082635 1.0 0.2183156968228176 2 O14936 1 +Amyloid precursor protein catabolic process 0.7911319450355054 2.099946261137555 0.0357335686492086 1.0 0.2205037494888568 13 Q9NQC3,Q15392,O95197 3 +Cartilage development involved in endochondral bone morphogenesis 0.7898400588196202 2.099930348355578 0.035734968633323 1.0 0.2205037494888568 4 O75844 1 +Mitochondrial electron transport ubiquinol to cytochrome c 0.7896980919641048 2.094808493872385 0.0361880197568105 1.0 0.2213547115819577 5 O14949,Q9UDW1 2 +Modification of postsynaptic actin cytoskeleton 0.7875382335360399 2.0897608780918335 0.0366392852836634 1.0 0.2226108828787874 4 Q9UQB8,Q7L576 2 +Positive regulation of epithelial cell apoptotic process 0.7872187724447799 2.0883486113703267 0.0367663994156759 1.0 0.2231692271045387 4 Q53EL6 1 +Lipophagy 0.7878901645464635 2.086783835464221 0.0369076789616367 1.0 0.2234683338215843 5 O15269,P42858 2 +Response to glycoside 0.7843416370106773 2.0862137357331805 0.0369592665657816 1.0 0.2234683338215843 2 P05023 1 +Cdp choline pathway 0.7846208615165612 2.081911232622678 0.0373505785902006 1.0 0.2247774136050345 3 Q9Y6K0,P35790 2 +Positive regulation of rig i signaling pathway 0.7831968672125424 2.0756347346888946 0.0379277463622145 1.0 0.2265298102708326 3 Q9NUD5,O75179 2 +Mitochondrial adp transmembrane transport 0.7824606009470249 2.0723878425362616 0.0382292862309481 1.0 0.2276421645653671 3 P12235 1 +Regulation of glial cell proliferation 0.7820332806579352 2.0705028618655392 0.0384052783219532 1.0 0.2278785100432752 3 Q96G23 1 +Positive regulation of t cell mediated cytotoxicity 0.7815661605619305 2.063323994317482 0.0390818558485375 1.0 0.2303829958252858 4 Q9NUQ9,P01889 2 +Regulation of t cell mediated cytotoxicity 0.7815661605619305 2.063323994317482 0.0390818558485375 1.0 0.2303829958252858 4 Q9NUQ9,P01889 2 +Regulation of cell maturation 0.7790035587188628 2.062767894304112 0.0391346857614844 1.0 0.2304800219986312 2 Q8IXJ6 1 +Positive regulation of glucose import 0.7812512703300478 2.0572569706097537 0.0396615140508096 1.0 0.2329332850231517 5 P31751,Q9BZF1,Q06124 3 +Positive regulation of glucose transmembrane transport 0.7812512703300478 2.0572569706097537 0.0396615140508096 1.0 0.2329332850231517 5 P31751,Q9BZF1,Q06124 3 +Negative regulation of multicellular organismal process 0.4083314581555116 2.052655443738588 0.0401060062209983 1.0 0.2351080124167128 94 P04083,Q07021,Q9NQC3,O14964,Q9UIQ6,Q4VCS5,P05023,P20020,P30536,O43823,P16989,Q16850,P16615,Q06124,P15260,P35080,Q8NCW5,P09601,Q9UBS4,Q96J02,Q96G23,Q53EL6,Q92945 23 +Sulfur compound transport 0.7807631193957656 2.0481834733874775 0.0405420251790735 1.0 0.2370062855717612 8 Q70HW3,Q9UBX3 2 +L alpha amino acid transmembrane transport 0.7805186434341501 2.047431833147644 0.0406157034876355 1.0 0.2372181686646511 11 Q9UJS0,P30825,Q9Y619,Q01650 4 +Protein transmembrane transport 0.7714931590002608 2.045989074265562 0.0407574456335717 1.0 0.2372923977690964 21 Q99595,Q9NS69,O60830,Q15388,O14925,Q07820,Q3ZCQ8,O95831,Q15629 9 +Mitochondrial transmembrane transport 0.697577981064264 2.0404838296995367 0.0413021599850578 1.0 0.237550689254026 45 Q99595,P12235,O60830,Q8IYU8,P21796,P23786,Q9Y619,P56134,Q9H2D1,O75964,Q9Y4W6,P24539,O95831,Q9BPX6,Q15388,O14925,Q9UJS0,O43772,Q00325,Q3ZCQ8,Q6P4A7 21 +Negative regulation of lymphocyte mediated immunity 0.774870680365863 2.0388504405563235 0.0414649563869238 1.0 0.2375799535478628 3 P01889 1 +Regulation of endoplasmic reticulum tubular network organization 0.7754172089208635 2.0360256160672776 0.0417477830888357 1.0 0.2385533827177206 4 Q15042,Q15041 2 +Phosphatidylinositol acyl chain remodeling 0.7734541422694153 2.032577874715189 0.0420951887054272 1.0 0.2398895780811984 3 Q96N66 1 +Lipoprotein localization 0.7748209873648727 2.02246659356937 0.0431281714025528 1.0 0.2430899827963017 7 Q13432,A6NIH7,Q96GC9 3 +Cerebellar cortex formation 0.774288809715419 2.021859333872775 0.0431908859667617 1.0 0.2430899827963017 6 Q7Z4L5,Q06124 2 +Endoplasmic reticulum tubular network organization 0.7745380240836595 2.0199783310381063 0.0433856352442192 1.0 0.2430899827963017 8 Q9NQC3 1 +Vitamin transmembrane transport 0.7723839239686913 2.0176737838285037 0.0436252468973099 1.0 0.2442165985761954 5 P38435,Q9HC21,Q9H2D1 3 +Purine containing compound transmembrane transport 0.7713115862022256 2.01287575508829 0.0441277017643328 1.0 0.2444090562760358 5 P12235,Q8TB61 2 +Regulation of dendrite extension 0.7689355684351412 2.012541276310126 0.0441629101509746 1.0 0.2444090562760358 3 Q9Y263 1 +Nucleotide transport 0.7729692045048451 2.0121930929271397 0.0441995863172379 1.0 0.2444090562760358 9 Q9HC21,Q9H2D1,Q8TB61 3 +Regulation of mitochondrial gene expression 0.7727332944727595 2.0111160477034087 0.0443132005067568 1.0 0.244548135061775 9 Q567V2 1 +L amino acid transport 0.7721308137689246 2.009900652129253 0.0444417047339551 1.0 0.244548135061775 12 Q9UJS0,P30825,Q9Y619,Q01650 4 +Response to endoplasmic reticulum stress 0.5172295362231787 1.9965220299199349 0.045877130280604 1.0 0.2498135170342582 73 P18031,O76024,Q9BUN8,O43765,Q9UBU6,Q8IXB1,O95831,Q96HY6,Q96CS3,Q9H3N1,O60313,P16615,Q4ZIN3,Q9Y4P3,Q96A33,Q96JB5,Q8TCT9,P27824,P46379,Q15363,Q13217,O15027,O95881,Q9GZP9,Q9Y679,Q9UM00 26 +Antigen processing and presentation of endogenous antigen 0.768496139961206 1.995812335041218 0.0459543536504294 1.0 0.2498135170342582 6 Q9NZ08,P01889,P04439,P10321 4 +Antigen processing and presentation of endogenous peptide antigen 0.768496139961206 1.995812335041218 0.0459543536504294 1.0 0.2498135170342582 6 Q9NZ08,P01889,P04439,P10321 4 +Mitochondrial calcium ion transmembrane transport 0.7685822753603746 1.9942705158054208 0.046122499561058 1.0 0.2504485709643973 7 Q9BPX6,P21796 2 +Metal ion transport 0.4040423928093111 1.9928592972639396 0.0462768564218989 1.0 0.2507756678317282 90 Q8IYU8,P62942,P21796,Q9HD20,Q8NEW0,O43865,O76024,P20020,P30536,O15173,Q9BPX6,Q13555,P16615,P42858,O14936,Q4KMQ2,O75844,Q96PU5,Q96GC9 19 +Leukotriene biosynthetic process 0.7622775800711726 1.9889199455079252 0.0467100398592823 1.0 0.2519161894368274 2 P09960 1 +Lipid droplet formation 0.7638888888888816 1.9846324479388369 0.0471853795093901 1.0 0.2533594439210762 4 Q9Y679,Q14534,O96017 3 +Mitochondrial respiratory chain complex assembly 0.7393053080613384 1.9759032863738792 0.0481657319236696 1.0 0.2567427305042877 30 O75880,P47985,Q9Y2R0,O43676,Q9H061,O96000,P03886,O95831,Q9Y6M9,Q96CU9,Q6DKK2,Q15070 12 +Endoplasmic reticulum membrane organization 0.7636567856625283 1.9719517520315613 0.0486151146086444 1.0 0.2567427305042877 7 Q9NQC3,Q15363,Q9P2W9 3 +Bergmann glial cell differentiation 0.761079172557294 1.9669716908804635 0.049186474523799 1.0 0.2567427305042877 5 P08670,Q7Z4L5,Q06124 3 +Response to angiotensin 0.7595989718711424 1.965437695442145 0.0493636001952539 1.0 0.2567427305042877 4 O43865 1 +Base excision repair ap site formation 0.7569395017793565 1.965229972557336 0.0493876263980948 1.0 0.2567427305042877 2 P13051 1 +Intracellular protein transmembrane transport 0.7583588734864128 1.9635849550183724 0.0495782435455698 1.0 0.2570775328159889 18 Q99595,Q15388,O60830,O14925,Q3ZCQ8,O95831,Q15629,P31751 8 +Tolerance induction 0.757246713808595 1.9605137500761567 0.0499357724424425 1.0 0.2576897312441027 3 P01889 1 +Regulation of tolerance induction 0.757246713808595 1.9605137500761567 0.0499357724424425 1.0 0.2576897312441027 3 P01889 1 +Negative regulation of blood circulation 0.7558920908354543 1.9544661334001148 0.0506461162311162 1.0 0.2596637852399545 3 P16615 1 +Negative regulation of amyloid precursor protein biosynthetic process 0.7533807829181639 1.949404347523354 0.0512471557549845 1.0 0.2612656685594021 2 Q9Y287 1 +Amyloid beta metabolic process 0.758739074549615 1.946588713866297 0.0515840627604677 1.0 0.2624590985052749 10 Q9NQC3,O95197 2 +C4 dicarboxylate transport 0.757313681737832 1.9453318862143416 0.0517350468063282 1.0 0.2624590985052749 6 Q9UBX3 1 +Positive regulation by symbiont of entry into host 0.7523131672597873 1.9446516435053267 0.0518169192014248 1.0 0.2624590985052749 2 P19474 1 +Atp metabolic process 0.3987548919052739 1.9430742681172253 0.0520071855524413 1.0 0.2628146210891712 97 P13073,O43676,P36404,P03886,P56134,P14406,P30536,O75964,P00403,Q9BRR6,P24539,P52789,Q7KZN9,P47985,O96000,Q9UDW1,Q9UJS0,Q9Y6M9,O14949,O75306 20 +Somatic diversification of immune receptors via somatic mutation 0.7562639155205257 1.940579689532706 0.0523092796190876 1.0 0.2635049257915685 6 Q9Y3Z3,Q9UQ84 2 +Regulation of sulfur metabolic process 0.7512455516014396 1.9398966307825944 0.052392253636506 1.0 0.2635049257915685 2 Q15120 1 +Magnesium ion homeostasis 0.7523501004967774 1.9386355049522 0.052545737050111 1.0 0.2636502312114201 3 Q8NE01 1 +Very long chain fatty acid metabolic process 0.7553103860241902 1.9340163946717597 0.0531111121390637 1.0 0.2643866551418053 7 Q9P035,Q9NZ01 2 +Inorganic anion transport 0.7499674332910864 1.9336783256668968 0.0531526903346473 1.0 0.2643866551418053 20 P21796,Q00325,Q9UHG3,P45880,Q9UBX3,P30536,Q9Y277 7 +Positive regulation of cholesterol biosynthetic process 0.7491103202847136 1.930379694623037 0.0535598089839051 1.0 0.265162898071099 2 P16435 1 +Positive regulation of cholesterol metabolic process 0.7491103202847136 1.930379694623037 0.0535598089839051 1.0 0.265162898071099 2 P16435 1 +Glycosphingolipid biosynthetic process 0.7491103202847128 1.930379694623037 0.0535598089839051 1.0 0.265162898071099 2 Q99805 1 +Positive regulation of alcohol biosynthetic process 0.7491103202847136 1.930379694623037 0.0535598089839051 1.0 0.265162898071099 2 P16435 1 +Positive regulation of catabolic process 0.3807980507329617 1.9281235065824631 0.0538397657868134 1.0 0.2659256397435987 133 P12235,Q969T7,P21796,O60506,O43765,O15269,Q8NF37,Q15042,Q9P0J0,Q96HY6,Q13190,Q4ZIN3,Q9NQT4,P42858,Q14103,Q96JB5,Q86UE4,Q6PKG0,P67809,P46379,O95376,Q9UJX6,P09601,Q96PU5,Q9H000,Q96J02,P31751,Q9H074,Q92945 29 +Mitochondrial electron transport cytochrome c to oxygen 0.753166006752013 1.9265425453167744 0.0540366647993604 1.0 0.26606864400431 6 P00403,Q7KZN9,P13073 3 +Response to increased oxygen levels 0.7540787029603673 1.9255748340170236 0.0541574835523943 1.0 0.2662490329956729 9 Q8N511 1 +Positive regulation of response to endoplasmic reticulum stress 0.7520028167943806 1.918943251335051 0.0549915161122416 1.0 0.2680624904640578 7 P18031,Q4ZIN3,O43765,P46379 4 +Endomembrane system organization 0.3700433171867235 1.917941037612025 0.0551184879337587 1.0 0.2684322365131114 152 P50402,Q9NQC3,O14964,Q9UQB8,P57088,O95197,Q86XL3,Q15041,O43765,Q9ULX6,Q5JRA6,Q15042,P40818,Q9P2W9,Q14155,O15260,Q8N5M9,P49755,P16615,Q13190,Q9Y3A6,P42858,Q96A33,O43760,Q4KMQ2,Q12907,Q15629,Q8N1F7,O75844,P46379,Q02750,Q15363,Q9BVK6,O15027,O14976,Q8NFQ8,Q96GC9,Q9Y3B3,P31751,Q9NPA0 40 +Histone h3 k36 trimethylation 0.7462633451957372 1.9176761597923635 0.0551520864667935 1.0 0.2684322365131114 2 Q96ST2 1 +Regulation of vesicle fusion 0.7474291601636647 1.910780249504364 0.0560328268687295 1.0 0.2714256007179481 4 P31751,P04083 2 +Glial cell proliferation 0.7473702819683983 1.9105150834052076 0.0560669262016402 1.0 0.2714256007179481 4 Q96G23 1 +Chloride transport 0.7505690463961414 1.908769998357562 0.0562917687197372 1.0 0.2720878654465976 10 Q9UHG3,P30536 2 +Regulation of amyloid precursor protein catabolic process 0.747844672008523 1.8960210243778184 0.0579572644915984 1.0 0.2765528791314254 11 Q9NQC3,O95197 2 +Adp transport 0.7434234021553054 1.892723873078109 0.058394599917128 1.0 0.2765528791314254 4 P12235 1 +Regulation of histone h3 k14 acetylation 0.7418612178954158 1.8916076355073903 0.0585432778077157 1.0 0.2768572772145481 3 Q03164 1 +Ion homeostasis 0.3945753246511452 1.8908592147566228 0.0586431400934484 1.0 0.2770625007244484 97 O75880,Q8IYU8,O43819,P62942,Q8N511,Q9HD20,Q8NEW0,O76024,P20020,P30536,Q9Y487,P30519,Q9Y4W6,Q93050,Q9Y5X3,Q9BPX6,P16615,Q8NE01,P42858,Q96A33,P09601,Q96PU5 22 +Estrogen biosynthetic process 0.7402135231316738 1.890627276610514 0.0586741164545068 1.0 0.2770625007244484 2 Q8NBQ5 1 +Amino acid import across plasma membrane 0.745302523197513 1.8883402795699205 0.0589802831265806 1.0 0.278093790307397 7 P30825,Q01650 2 +Peptide catabolic process 0.7457247837707629 1.8862803498048344 0.0592571858193804 1.0 0.2787716871951239 10 P42892,P55786,P09960,Q9UIQ6,Q99829,Q9NZ08 6 +Collagen biosynthetic process 0.74130477431449 1.883160942853115 0.0596785602860789 1.0 0.2799896303177027 4 P08670,Q92791 2 +Mitochondrion distribution 0.7401083638130396 1.8777567073802104 0.0604144551856555 1.0 0.2802682302426789 4 O75153 1 +Intraciliary transport involved in cilium assembly 0.7370106761565853 1.8762778373900748 0.0606171386578395 1.0 0.2810027854240888 2 A0AVF1 1 +Retina morphogenesis in camera type eye 0.7381196083688136 1.8747785482032315 0.0608231955449127 1.0 0.2813405767650455 3 Q8NBN7 1 +Eye photoreceptor cell development 0.7381196083688136 1.8747785482032315 0.0608231955449127 1.0 0.2813405767650455 3 Q8NBN7 1 +Negative regulation of vascular associated smooth muscle cell migration 0.7359430604982196 1.8714901917528803 0.0612771681038775 1.0 0.2821503936053759 2 P09493 1 +Positive regulation of striated muscle contraction 0.7348754448398558 1.8667003047228028 0.0619434511757961 1.0 0.283419241950195 2 P05023 1 +Cerebellar granular layer morphogenesis 0.734519572953737 1.86510317849805 0.0621669431357834 1.0 0.2834803579540556 2 Q15058 1 +Cerebellar granular layer development 0.734519572953737 1.86510317849805 0.0621669431357834 1.0 0.2834803579540556 2 Q15058 1 +Peptidyl proline hydroxylation 0.738564807922077 1.860119644830713 0.0628686004001182 1.0 0.2845702290968208 6 Q32P28,P13674 2 +Negative regulation of glycoprotein metabolic process 0.7346419510389535 1.8591118549544257 0.0630112852503366 1.0 0.2845992834438392 3 Q9Y287 1 +Endoplasmic reticulum calcium ion homeostasis 0.7382075840165367 1.858489219717437 0.0630995728639094 1.0 0.2845992834438392 6 O76024,P16615,Q96A33 3 +Nitrogen compound transport 0.3378977395714445 1.8546877618448745 0.0636408273845352 1.0 0.2862774914779697 521 Q99595,Q9NS69,O60830,O60725,A6NIH7,Q9HD20,Q8N4H5,P43307,Q9H2D1,Q9Y282,P55786,Q13432,O95831,O15173,Q9P2W9,P30825,Q16850,Q9Y5M8,Q96L92,Q8TB61,Q15629,P46379,Q9BTX1,O43772,Q32P28,Q96GC9,Q6P4A7,Q9Y277,P04083,Q08J23,O43865,Q9Y619,Q9ULX6,O43823,P53992,Q8NFH4,Q96CS3,P04792,O15260,Q15070,Q15388,Q06124,O14925,Q15005,Q96KC8,Q8TCT9,Q07820,O15027,Q5JRX3,Q3ZCQ8,P55735,Q9Y3B3,P31751,Q92945,P50402,Q9NZJ7,Q9BUN8,P30536,O95070,Q9BW83,Q9Y5X3,P53985,Q13555,Q13190,Q9HC21,Q9UGP8,Q14168,Q12907,P40855,Q8N1F7,Q9UJS0,P51809,P67809,Q15363,Q8TB36,Q9Y4C2,Q9GZP9,Q9Y679,Q9Y2T2,Q01650,P12235,Q96ST2,Q14C86,Q15041,P22626,O43765,Q9Y678,Q96PC5,Q15042,Q9P0J0,Q8N5M9,P49755,Q9Y3A6,L0R6Q1,Q07666,O75312,Q7Z4Q2,Q8TD16,P27824,Q9HCU5,Q9BVK6,O95376,Q8IUD2,Q53H12,Q12769,Q07955,Q9Y6M1 107 +Cerebral cortex cell migration 0.7382838277306671 1.85409737908884 0.0637252296164443 1.0 0.2864019716875232 8 Q9NQC3 1 +Negative regulation of alpha beta t cell activation 0.7353249238498607 1.8504859033217411 0.0642435479380378 1.0 0.2883205895998766 5 P04083 1 +Cellular response to vascular endothelial growth factor stimulus 0.7340179389560431 1.8502020686521297 0.0642844309303896 1.0 0.2883205895998766 4 P04083 1 +Regulation of golgi organization 0.7339181490978781 1.8440848393735467 0.0651707770060232 1.0 0.2900191108758211 5 Q9P2W9,Q13190 2 +Regulation of cell death 0.3386109776862404 1.8410501007385691 0.0656142170961586 1.0 0.291174575447029 306 Q9NS69,P12235,P04083,Q9UMX5,Q9NZJ7,Q9NQC3,Q01105,P61289,P21796,O15118,P49327,O76024,Q15041,Q86XL3,P45880,Q15392,P30536,P00403,O15269,Q9BXK5,P61978,P30154,P16989,Q96K76,O95831,Q96HY6,Q14155,P04792,O60313,O60443,Q9NR28,Q4ZIN3,Q96A26,P42858,Q15418,Q4KMQ2,Q99720,Q86UE4,P51812,Q9NXR7,P46379,Q9NVI7,Q07820,Q13217,P09601,Q96J02,Q9Y6C9,P31751,P16435,Q53EL6 50 +Regulation of dna templated transcription in response to stress 0.7355264830740955 1.838776816446044 0.0659480195235342 1.0 0.2916347520730192 10 P09601,Q15418 2 +Er associated misfolded protein catabolic process 0.7338077059878567 1.8383867755446783 0.0660054324088554 1.0 0.2916850942642379 6 Q9BUN8,P46379 2 +Ethanol catabolic process 0.7274021352313325 1.8331087729824231 0.0667863967223052 1.0 0.2937051669017548 2 P30837 1 +Primary alcohol catabolic process 0.7274021352313325 1.8331087729824231 0.0667863967223052 1.0 0.2937051669017548 2 P30837 1 +Regulation of calcium ion dependent exocytosis 0.7315070261281986 1.833104793537804 0.0667869884023084 1.0 0.2937051669017548 5 P16615 1 +Purine deoxyribonucleotide metabolic process 0.7288101327586816 1.8327866107440296 0.0668343110847433 1.0 0.2937094516948812 3 Q9Y3Z3 1 +Cellular iron ion homeostasis 0.7339506303244175 1.8310847793738612 0.0670878899710021 1.0 0.2944154838962884 12 Q8N511,Q9Y487 2 +Regulation of immune response 0.3838960605377745 1.8294981519038336 0.0673250159184331 1.0 0.295047459111418 112 Q96IZ0,P04083,Q07021,P18031,Q9NQC3,Q15233,Q9UKG1,P62942,O96028,P01889,Q5RKV6,Q9NUQ9,O43657,Q9NPR9,Q96PK6,O75179,Q9NZ08,Q9NUD5,Q06124,P04439,Q9Y3Z3,P19474,P17931,Q07666,P05771,Q96FZ2,P51812,Q9NR50,P51809,P46379,Q14671,P09601,Q9H000,Q96J02,P43243 35 +Thymus development 0.730327207660594 1.8196151857631555 0.0688176274479563 1.0 0.299929370796217 7 O95067,O75844 2 +Cristae formation 0.7307417974322451 1.819251415610884 0.0688730819061413 1.0 0.299963339094946 8 Q5XKP0,Q9Y4W6,Q9NX63,O95202,Q9NVH1,Q6UXV4,Q9Y512 7 +Antigen processing and presentation of peptide antigen via mhc class i 0.7303247052561063 1.8156059260342192 0.0694308439272111 1.0 0.3008248534272899 9 P04439,Q9UIQ6,Q9NZ08,P01889,P10321 5 +Positive regulation of autophagy of mitochondrion 0.7287364892680294 1.8151698973869488 0.0694978042319003 1.0 0.3008248534272899 6 P42858,P21796 2 +Amino acid transmembrane transport 0.730295021869697 1.814439475328224 0.0696100929285186 1.0 0.300842411287616 13 Q9UJS0,P30825,Q9Y619,Q01650 4 +Positive regulation of cell death 0.3855205136797824 1.8124952681228204 0.0699097044239407 1.0 0.3013243295249968 106 Q9NR28,Q9NS69,P00403,P04083,Q07820,Q9NZJ7,Q96A26,P42858,P09601,O95831,Q14155,Q9Y6C9,O60443,Q53EL6,P30536 15 +Cop9 signalosome assembly 0.7227758007117417 1.8122599144602105 0.0699460452471627 1.0 0.3013243295249968 2 Q99627 1 +Protein localization to endoplasmic reticulum exit site 0.7246284257915501 1.8075794024645553 0.0706719863771565 1.0 0.3020751361025695 4 O15027 1 +Regulation of erad pathway 0.7269856815192584 1.8071427841539265 0.0707400192482583 1.0 0.3020751361025695 6 Q4ZIN3 1 +Glyoxylate metabolic process 0.7227448387342477 1.8053376350243588 0.0710218637748578 1.0 0.3026668128724104 3 P48735 1 +Steroid catabolic process 0.7216535321939181 1.800391367109864 0.0717988629985415 1.0 0.304340732322246 3 Q8WTV0 1 +Homologous chromosome pairing at meiosis 0.7260693864303417 1.7976074778483335 0.0722392325008205 1.0 0.3051866775717998 8 Q9BTX1,P46379 2 +Tetrapyrrole catabolic process 0.7236331727465259 1.797169298561181 0.0723087469278507 1.0 0.3052516229862259 5 P30519 1 +Iron ion homeostasis 0.7251923718289232 1.79532066314911 0.0726026247116577 1.0 0.3054998889759465 16 Q8N511,Q9Y487,P30519 3 +Integrated stress response signaling 0.7215782798395549 1.7936970651534778 0.0728615340123277 1.0 0.3061827195199741 4 P18031,Q15363 2 +Perk mediated unfolded protein response 0.7215782798395549 1.7936970651534778 0.0728615340123277 1.0 0.3061827195199741 4 P18031,Q15363 2 +Protein insertion into mitochondrial inner membrane 0.719833711296484 1.7921381329297967 0.073110841869511 1.0 0.3068234469715836 3 Q9P0J0 1 +Cellular homeostasis 0.3733693263128762 1.7893701703795313 0.0735552200346127 1.0 0.3076175816829411 129 O75880,Q8IYU8,Q9NQC3,P62995,O43819,P62942,Q8N511,Q9HD20,Q7L7X3,Q8NEW0,O76024,P20020,Q9Y487,Q9Y4W6,Q93050,P52789,P06576,Q9BPX6,P16615,P42858,Q9Y263,Q96A33,Q4KMQ2,Q07820,P09601,Q15120,Q96PU5 27 +Amyloid precursor protein metabolic process 0.7238577777978741 1.7888444355938011 0.0736398724022442 1.0 0.3076175816829411 16 Q9NQC3,Q15392,O95197 3 +Prostate gland growth 0.7188735070499368 1.7877808998372586 0.0738113635944421 1.0 0.308130837350448 3 Q9NZJ7 1 +Programmed cell death 0.3325323709846664 1.7867715930418249 0.0739744124010441 1.0 0.308315135837023 365 Q9NS69,Q03164,P04083,Q14728,Q9NZJ7,Q9NQC3,P21796,O14681,Q7L7X3,O43865,O76024,O95197,Q86XL3,P45880,Q96KA5,Q15392,P30536,O15269,P61978,Q96K76,O95831,Q96HY6,Q14155,P04792,O60313,O60443,Q9NR28,Q96A26,P42858,Q15418,P51114,Q99720,Q86UE4,P51812,O75844,P46379,Q96RU2,Q07820,O95470,P09601,Q3ZCQ8,Q96J02,Q9Y6C9,P31751,P16435,Q53EL6 46 +Macroautophagy 0.3863838309279924 1.781493787175298 0.0748318189462857 1.0 0.310143385652461 94 P12235,P50851,P21796,O14681,O15118,Q9Y487,O15269,Q93050,Q15042,Q96HY6,Q9Y5X3,P16615,P42858,Q9Y263,Q8NHS3,P51809,Q6PKG0,Q86VR2,P09601,Q96GC9,Q9Y679 21 +Synaptonemal complex organization 0.7211231122553744 1.7802211059638855 0.0750397825985107 1.0 0.3105099700732871 6 P46379 1 +Antigen processing and presentation of peptide antigen 0.7224517568217077 1.7775691432027425 0.0754746454332382 1.0 0.3105099700732871 10 P04439,Q9UIQ6,Q9NZ08,P01889,P10321 5 +Regulation of cellular response to osmotic stress 0.717451471213761 1.7748863494812872 0.0759166546587706 1.0 0.3115827982983351 4 Q9BPX6 1 +Neutrophil differentiation 0.7173165363814571 1.7742707514181475 0.0760183761317419 1.0 0.3117983492212611 4 P49327,Q8N5M9 2 +Positive regulation of pattern recognition receptor signaling pathway 0.7209674176474694 1.7739252852951708 0.0760755096728926 1.0 0.3118308569192243 8 Q9NQC3,O75179 2 +Epithelial cell differentiation involved in prostate gland development 0.7152860152504773 1.771486180430185 0.0764798887562487 1.0 0.3130188706466283 3 Q9NZJ7 1 +Amyloid precursor protein biosynthetic process 0.7167030682945905 1.771471564533185 0.0764823171978166 1.0 0.3130188706466283 4 Q96IZ0,Q9Y287 2 +Regulation of response to osmotic stress 0.7168840828743565 1.7662727293004583 0.0773501044596349 1.0 0.3148154219400814 5 Q9BPX6 1 +Forebrain cell migration 0.719553207521465 1.7653680782770438 0.0775019246906478 1.0 0.3152308708373784 9 Q9NQC3 1 +Regulation of collagen metabolic process 0.7134565063830458 1.7631671292394546 0.0778723059522952 1.0 0.3165341903910807 3 P08670 1 +Copi coated vesicle budding 0.7154330082403759 1.7596186721162683 0.0784724834553927 1.0 0.3175187739513956 5 P49755,Q9BVK6,Q15363 3 +Golgi vesicle budding 0.7154330082403759 1.7596186721162683 0.0784724834553927 1.0 0.3175187739513956 5 P49755,Q9BVK6,Q15363 3 +Negative regulation of insulin secretion involved in cellular response to glucose stimulus 0.7103202846975195 1.7559270867580252 0.0791008592378883 1.0 0.318869048976144 2 Q8N5M9 1 +Cerebellar purkinje cell layer morphogenesis 0.7114307716918405 1.7539485752301842 0.0794393191572124 1.0 0.3196234701582574 3 Q7Z4L5 1 +Positive regulation of epithelial to mesenchymal transition 0.7121697095475885 1.7507646110203627 0.0799864647940977 1.0 0.3210367662202462 4 Q92769 1 +Negative regulation of cell death 0.3571848603407543 1.7475021515015776 0.0805502720292856 1.0 0.3210367662202462 190 P12235,P04083,Q9UMX5,Q01105,P61289,P21796,O15118,P49327,O76024,Q15041,Q86XL3,P45880,Q15392,P61978,P16989,Q96K76,Q9P0J0,Q96HY6,P04792,O60313,P13051,Q4ZIN3,P42858,Q15418,O75312,Q86UE4,P51812,Q9NXR7,P46379,Q92769,Q9NVI7,Q6FI81,Q07820,Q13217,P09601,Q96J02,P31751,P16435,Q53EL6 39 +Cardiac atrium development 0.7071174377224355 1.7413949951067145 0.0816143649014899 1.0 0.3210367662202462 2 O96028 1 +Hepatocyte apoptotic process 0.7071174377224207 1.7413949951066472 0.0816143649015017 1.0 0.3210367662202462 2 Q13131 1 +Regulation of hepatocyte apoptotic process 0.7071174377224207 1.7413949951066472 0.0816143649015017 1.0 0.3210367662202462 2 Q13131 1 +Negative regulation of hepatocyte apoptotic process 0.7071174377224207 1.7413949951066472 0.0816143649015017 1.0 0.3210367662202462 2 Q13131 1 +Regulation of skeletal muscle adaptation 0.7076586056288754 1.736762408679268 0.0824291168478574 1.0 0.3217126764289043 3 P16615 1 +Skeletal muscle adaptation 0.7076586056288754 1.736762408679268 0.0824291168478574 1.0 0.3217126764289043 3 P16615 1 +Positive regulation of steroid metabolic process 0.7073691705233328 1.7354426563168563 0.0826624301478686 1.0 0.3217126764289043 3 Q13131,P16435 2 +Positive regulation of steroid biosynthetic process 0.7073691705233328 1.7354426563168563 0.0826624301478686 1.0 0.3217126764289043 3 Q13131,P16435 2 +Regulation of hormone biosynthetic process 0.707369170523331 1.7354426563168488 0.08266243014787 1.0 0.3217126764289043 3 P05023,P16435 2 +Regulation of steroid hormone biosynthetic process 0.707369170523331 1.7354426563168488 0.08266243014787 1.0 0.3217126764289043 3 P05023,P16435 2 +Chemical homeostasis 0.3579602915478025 1.730558810195446 0.0835304835149768 1.0 0.3236033834746522 162 O75880,Q9P035,Q8IYU8,Q9NQC3,P42785,P62995,O43819,P62942,Q8N511,O15118,Q9HD20,Q8NEW0,O76024,P20020,Q9Y487,P30519,P30536,Q9Y4W6,Q93050,Q8NF37,P52789,Q9Y5X3,P06576,O15260,Q9BPX6,P53985,P16615,Q06124,Q8NE01,P42858,Q5BJF2,Q96A33,O15254,Q15067,P09601,Q15120,Q96PU5,Q9Y6C9 38 +Regulation of glucose import 0.7116959281612555 1.728581536048427 0.0838840165603915 1.0 0.3241298859409764 9 P31751,Q9BZF1,Q06124,P52789 4 +Positive regulation of macroautophagy 0.7110202849963402 1.7263649119599274 0.0842817841226839 1.0 0.3252701985295055 16 P12235,O15269,Q15042,P21796,P42858,P09601 6 +Negative regulation of muscle tissue development 0.7049726157534215 1.7245091332797529 0.0846159715957766 1.0 0.3257321863219916 3 P16989 1 +Negative regulation of muscle organ development 0.7049726157534215 1.7245091332797529 0.0846159715957766 1.0 0.3257321863219916 3 P16989 1 +Maintenance of protein location in mitochondrion 0.7049209690033775 1.724273397242568 0.0846584994275398 1.0 0.3257321863219916 3 P30536 1 +Positive regulation of neuron apoptotic process 0.7086029017143166 1.7163270427949902 0.0861022014197498 1.0 0.3294772448500991 8 O95831 1 +Vascular associated smooth muscle cell migration 0.7019767044322833 1.710826713561584 0.0871131066333978 1.0 0.3313539956397613 3 P09493 1 +Postsynaptic modulation of chemical synaptic transmission 0.7024080673969987 1.7060486594994069 0.0879990202527922 1.0 0.3332425890024047 4 P40818 1 +Homologous chromosome segregation 0.7063645982549582 1.703555422675351 0.088464175500587 1.0 0.3344853700162411 9 Q9BTX1,P46379 2 +Regulation of protein tyrosine kinase activity 0.7066202444069684 1.7030128819285488 0.0885656577003022 1.0 0.3346693934685839 10 O95684 1 +Modification of synaptic structure 0.7045687428688568 1.7003887804131212 0.0890578208017058 1.0 0.3359566988614539 7 Q9UQB8,O00264,Q7L576 3 +Carnitine metabolic process 0.699459271764267 1.6925072497635778 0.0905492989944818 1.0 0.3395330814958766 4 P23786 1 +Nadh dehydrogenase complex assembly 0.6985198782738768 1.6882914739085382 0.0913552910978117 1.0 0.3415448257739426 22 O43676,Q9H061,P03886,Q96CU9,Q15070,Q9Y6M9 6 +Insulin processing 0.6953736654804272 1.6879528654747051 0.0914202772889716 1.0 0.3415862601298426 2 Q969M3 1 +Torc1 signaling 0.7009823081147961 1.6872424738083884 0.0915567373801504 1.0 0.3416372389481585 6 Q8NHS3,Q6PKG0 2 +Dna templated transcription termination 0.7012540858867327 1.6849574747938525 0.0919967763798523 1.0 0.3423197941767985 7 O75844 1 +Apoptotic signaling pathway 0.3690207884887618 1.6844272032512888 0.0920991371720012 1.0 0.3423197941767985 122 Q9NR28,Q96RU2,P61978,Q07820,O95470,Q96A26,P42858,P09601,Q3ZCQ8,Q96K76,O76024,O95831,P45880,P04792,O60313,O60443,P46379 17 +Signaling receptor ligand precursor processing 0.6956212175151328 1.6817483966088962 0.0926176390324859 1.0 0.34355150032358 3 Q969M3,P42892 2 +Regulation of jun kinase activity 0.6969667770807968 1.6810493372481532 0.0927533318003939 1.0 0.34355150032358 4 Q53EL6 1 +Lysosomal protein catabolic process 0.6991497189085618 1.6787460526854443 0.0932015465060356 1.0 0.3443837902091824 6 Q8N511 1 +Protein catabolic process in the vacuole 0.6991497189085618 1.6787460526854443 0.0932015465060356 1.0 0.3443837902091824 6 Q8N511 1 +Response to oxidative stress 0.3955012142846609 1.677888231559968 0.0933689203818757 1.0 0.3445683861851488 84 Q9NR28,P04083,P16615,P28074,O43169,P09601,O95831,Q99720,P04792,Q15392,P30519 11 +Post translational protein modification 0.7012806063327948 1.6777614602241817 0.0933936758277418 1.0 0.3445683861851488 10 Q32P28,P46977,O60725 3 +Regulation of autophagy 0.4204976245664826 1.6776541945322443 0.0934146263951531 1.0 0.3445683861851488 81 O15269,Q8TEY7,Q07820,Q9NZJ7,Q93050,P21796,P42858,P09601,Q9Y487,Q8NHS3,Q86UE4,P04792,O75844,P30536 14 +Cerebellar cortex morphogenesis 0.6995177636710698 1.6768662871494775 0.0935686318903532 1.0 0.3448549872619703 7 Q02750,Q7Z4L5,Q06124,Q15058 4 +Protein catabolic process 0.3383683497675296 1.6766999812897154 0.0936011642876106 1.0 0.3448549872619703 246 P60900,Q8N511,Q9UIQ6,Q9NUJ1,O76024,Q9UHG3,Q9BUN8,Q9UBU6,Q8TEY7,P28074,Q8NF37,O60502,Q16740,Q96K76,Q96HY6,P40818,Q96CS3,Q9Y5X3,P28072,Q16850,Q13190,Q4ZIN3,Q9Y263,Q96A33,Q96JB5,Q8NHS3,Q8TCT9,Q99436,O75844,P46379,P49721,Q96RU2,Q9UJX4,Q13217,Q9GZP9,Q15369,Q96PU5,Q9H000,Q96J02 39 +Retinal rod cell development 0.6903914590747465 1.6652074601056333 0.0958713731410716 1.0 0.3495609272698337 2 P54802 1 +Retinal rod cell differentiation 0.6903914590747465 1.6652074601056333 0.0958713731410716 1.0 0.3495609272698337 2 P54802 1 +Camera type eye photoreceptor cell differentiation 0.6903914590747465 1.6652074601056333 0.0958713731410716 1.0 0.3495609272698337 2 P54802 1 +Neuromuscular synaptic transmission 0.6900355871886231 1.6635811647647467 0.096196158502857 1.0 0.3505434482073633 2 Q8IUD2 1 +Negative regulation of response to wounding 0.6933434492245336 1.6578519622107306 0.0973473501839268 1.0 0.3513312705762887 5 Q96G23 1 +Regulation of receptor catabolic process 0.688616702586909 1.6496196351216643 0.0990207564541623 1.0 0.3537173244926869 3 Q96J02 1 +Positive regulation of nlrp3 inflammasome complex assembly 0.6868327402135241 1.6489348948657452 0.0991609733543084 1.0 0.3538193063886556 2 Q9H6R0 1 +Striated muscle adaptation 0.6896961511328418 1.647565288652163 0.0994419083024351 1.0 0.3540950106746097 4 P16615 1 +I kappab phosphorylation 0.6881392514577129 1.6474266065656935 0.0994703902755809 1.0 0.3540950106746097 3 Q96HY6 1 +Regulation of post translational protein modification 0.6880596307968163 1.6470608558444086 0.0995455379157335 1.0 0.3540950106746097 3 Q32P28 1 +Regulation of glucose transmembrane transport 0.6945732481822272 1.645969737823093 0.0997699896244381 1.0 0.3543959777186461 10 Q06124,Q9UKG1,P52789,P31751,Q9BZF1 5 +Cerebellar purkinje cell layer development 0.6922904667022753 1.6431309714021862 0.1003558380889944 1.0 0.3554806852822569 7 O14949,Q7Z4L5,P54802 3 +Er nucleus signaling pathway 0.6942982576252938 1.6422513234510565 0.1005379303288513 1.0 0.3558142196014434 12 Q15363,P16615,P18031,Q96A33,O76024,Q9UM00 6 +Regulation of hormone metabolic process 0.6912671377848169 1.6421337164144114 0.1005622956140421 1.0 0.3558142196014434 6 O75844,P16435,O60678 3 +Purine nucleotide transport 0.6912023725649832 1.6380442518152862 0.1014124629726711 1.0 0.3569564540026329 7 P12235,Q8TB61 2 +Glycolipid biosynthetic process 0.6915304161105073 1.6363404382551767 0.1017683572637595 1.0 0.3572886869697752 8 Q8NBX0,O43292 2 +Positive regulation of anion transmembrane transport 0.6866550495702872 1.6335333315132614 0.1023568764279021 1.0 0.3583621690185723 4 Q9Y4C2 1 +Enzyme linked receptor protein signaling pathway 0.3740491620805956 1.6292457788006087 0.103260999384886 1.0 0.3589415300592096 96 P18031,O14964,Q9NQC3,Q9UKG1,Q9UQB8,P62942,Q9UIQ6,P08670,Q15750,Q96PK6,Q9Y5X3,Q14155,P04792,Q9BZF1,Q8IXJ6,P11802,Q06124,Q92572,P43490,Q92896,Q8N1F7,O95470,Q7L576,P31751,Q53EL6 25 +Embryonic heart tube development 0.6855255406820233 1.6283177552849208 0.1034575265677624 1.0 0.3589415300592096 4 Q15363 1 +Regulation of dna methylation 0.6890570271800612 1.6247103703505112 0.1042242866369882 1.0 0.3601250296720799 8 Q03164,O75844 2 +Endoplasmic reticulum organization 0.6564268520761444 1.6244074428954292 0.1042888796461583 1.0 0.3601518421349892 37 Q9NQC3,P57088,O95197,Q15041,O43765,Q5JRA6,O00429,Q15042,Q9P2W9,Q8N5M9,Q96A33,Q12907,Q15629,P46379,Q15363,O15027,Q8NFQ8,O14976,Q9NPA0 19 +Regulation of secondary metabolic process 0.6807829181494779 1.6212232635691173 0.1049697652902663 1.0 0.3617147377076769 2 Q9UKG1 1 +Hydrogen peroxide biosynthetic process 0.6819499404215177 1.6189637142925262 0.1054550705884957 1.0 0.36306810540496 3 P00403 1 +Protein insertion into er membrane 0.6886170482479753 1.6160299278752954 0.1060878427381468 1.0 0.3634388980426595 11 O43765,P46379,Q15629,Q96A33 4 +Protein localization to mitochondrion 0.5891974666329992 1.6159962658186324 0.1060951205538094 1.0 0.3634388980426595 54 Q99595,Q9NS69,O60830,Q15388,P55786,O14925,Q5JRX3,Q3ZCQ8,Q8N4H5,O95831,Q9Y6C9,Q15070 12 +Regulation of er to golgi vesicle mediated transport 0.6842490946281461 1.6157077946522302 0.1061575049322756 1.0 0.3634388980426595 5 Q9HCU5,Q9NR31,Q9P2W9 3 +Mitochondrial calcium ion homeostasis 0.6868534160320974 1.6143402028984426 0.1064536543576584 1.0 0.3634681075778456 8 Q9BPX6 1 +Nuclear pore complex assembly 0.687288862032567 1.6135949710818838 0.1066153083710799 1.0 0.3636165904085686 9 Q9NQC3 1 +Vacuolar acidification 0.6871220935785016 1.6128057416435713 0.1067867183233342 1.0 0.3638212010833165 9 Q8N511,Q9Y487 2 +Negative regulation of amyloid beta clearance 0.6820613477010313 1.6123086206633666 0.1068947983294241 1.0 0.3639937329465669 4 Q16850 1 +Protein targeting to peroxisome 0.67782128871486 1.5999426410173752 0.1096113085954817 1.0 0.3702921093710755 3 Q9UJ83,P40855 2 +Regulation of protein folding 0.6774652901388455 1.5983012538766324 0.1099759484992537 1.0 0.3702921093710755 3 Q9H2J4,O14737 2 +Positive regulation of anion transport 0.6825158920167504 1.5973653032512198 0.1101843019323878 1.0 0.3702921093710755 7 Q9Y4C2,Q15041 2 +Response to dietary excess 0.6743772241992882 1.5918171583739464 0.1114257936378175 1.0 0.3724183830605786 2 Q06481 1 +Positive regulation of myotube differentiation 0.6743772241992871 1.5918171583739416 0.1114257936378186 1.0 0.3724183830605786 2 P42345 1 +Neutrophil degranulation 0.6758957147273998 1.5910621071467708 0.111595599233675 1.0 0.3725928937533185 3 P51809 1 +Neutrophil activation involved in immune response 0.6758957147273998 1.5910621071467708 0.111595599233675 1.0 0.3725928937533185 3 P51809 1 +Response to interleukin 12 0.6740213523131662 1.5901815920052502 0.111793878582078 1.0 0.3730583510134956 2 P07237 1 +Negative regulation of interleukin 12 production 0.6729537366548204 1.5852737160181216 0.1129041581883401 1.0 0.3757739760711718 2 Q07021 1 +Fc gamma receptor signaling pathway 0.6742613029547854 1.5835198420239005 0.1133030278079116 1.0 0.3762030114369057 3 Q06481,Q9UKG1 2 +Regulation of fc gamma receptor signaling pathway involved in phagocytosis 0.6742613029547854 1.5835198420239005 0.1133030278079116 1.0 0.3762030114369057 3 Q06481,Q9UKG1 2 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.6818953746532631 1.5825961675910092 0.1135135375729547 1.0 0.3766153338218924 12 Q9NR28,Q96A26,O95831,Q9NZJ7 4 +Mammary gland epithelium development 0.6782619075204067 1.5815015431763118 0.1137634063817016 1.0 0.3771324783341859 6 Q9NQC3 1 +Negative regulation of cell killing 0.6733080594306748 1.5791190353686786 0.1143087562827429 1.0 0.3780660691877568 3 P01889 1 +Cellular response to mineralocorticoid stimulus 0.6745546977149848 1.5775522283462542 0.1146685145047488 1.0 0.3786630413843633 4 O95831 1 +Astrocyte development 0.6755196775913912 1.5751283467598804 0.1152268221551517 1.0 0.3798800786349883 5 P15260 1 +Dicarboxylic acid transport 0.6800851651391779 1.5731426351833224 0.1156857946223466 1.0 0.3808316262450963 13 Q9H2D1,Q9UBX3,Q9UJS0,Q15041 4 +Metal ion homeostasis 0.4705881020047249 1.5718113759539123 0.1159943024918381 1.0 0.3814841587061096 73 O75880,Q8IYU8,O43819,P62942,Q8N511,Q9HD20,Q8NEW0,O76024,P20020,Q9Y487,P30519,Q9Y5X3,Q9BPX6,P16615,Q8NE01,P42858,Q96A33,P09601,Q96PU5 19 +Organic acid transmembrane transport 0.6685361594481467 1.568036388910966 0.1168726402833839 1.0 0.3821636096779625 27 P30825,Q01650,O43772,P31751,Q9UJS0,P23786,Q9Y619,Q9H2D1,Q9UBX3,P53985 10 +Cell proliferation in forebrain 0.6722661105627779 1.566938466515713 0.1171290752891849 1.0 0.3823462930643067 4 Q15058 1 +Arf protein signal transduction 0.6705840455840477 1.55913250924264 0.1189650206614605 1.0 0.3866058132982951 4 Q6DN90,Q8N6T3,Q15555 3 +Peptidyl arginine modification 0.67253901717387 1.5547357337841512 0.120009020450037 1.0 0.389131635419475 6 Q9ULX3,Q86X55 2 +Negative regulation of gliogenesis 0.6688995277761443 1.5442755010385842 0.1225216049748687 1.0 0.3942185346320894 5 Q96G23,P30536 2 +Early endosome to golgi transport 0.6700809397162958 1.5432241752549023 0.1227763935865242 1.0 0.394340601195035 6 O15260,Q13190 2 +Regulation of pattern recognition receptor signaling pathway 0.6730534467967205 1.5397589063624073 0.1236191321316699 1.0 0.3960437008687526 16 Q9NQC3,O75179,Q9NPR9,O43657 4 +Synaptic membrane adhesion 0.6619217081850525 1.534458482093172 0.1249168997111498 1.0 0.3991406064055033 2 Q16539 1 +Bile acid and bile salt transport 0.6601423487544466 1.5262458786846715 0.1269486415950234 1.0 0.401033669884179 2 Q13131 1 +Neurotrophin trk receptor signaling pathway 0.6633515611714765 1.525521209961609 0.1271291474108182 1.0 0.4014037903051098 4 Q06124 1 +Glycerol ether metabolic process 0.6658731176752535 1.5234977482671028 0.1276342236219987 1.0 0.4023970522848785 6 P49327,O00116 2 +Negative regulation of endoplasmic reticulum unfolded protein response 0.6642804858486433 1.5227104609119395 0.1278311596477817 1.0 0.4026173253916464 5 O76024,Q96HY6 2 +Chondrocyte proliferation 0.6587188612099697 1.5196725984948285 0.128593281696983 1.0 0.4043474943697038 2 Q14789 1 +Regulation of response to extracellular stimulus 0.6614772669239426 1.5167986304440568 0.1293175329421534 1.0 0.4056951423346484 4 P80303 1 +Attachment of gpi anchor to protein 0.6611203054521458 1.5151368493364803 0.1297377515055859 1.0 0.4061944073852849 4 Q92643,O43292 2 +Peroxisomal transport 0.6606125356125325 1.5127726982369705 0.1303374060398008 1.0 0.4061944073852849 4 Q9UJ83,O75381,P40855 3 +Negative regulation of immune effector process 0.6657247460587494 1.5111775795222844 0.1307432130958041 1.0 0.4069350399745142 9 P04083,P04439,Q9UKG1,P09601,P01889 5 +Cellular protein catabolic process 0.3405809627763006 1.5083889256517058 0.1314550156786988 1.0 0.4077512700373156 211 P60900,Q8N511,O76024,Q9UHG3,Q9BUN8,Q9UBU6,Q8TEY7,P28074,Q16740,Q96K76,Q96HY6,P40818,Q96CS3,Q9Y5X3,P28072,Q4ZIN3,Q9Y263,Q96A33,Q96JB5,Q8NHS3,Q8TCT9,Q99436,O75844,Q96RU2,P49721,P46379,Q9UJX4,Q13217,Q9GZP9,Q15369,Q96PU5,Q9H000,Q96J02,Q9Y679 34 +Regulation of cell communication by electrical coupling 0.6555160142348735 1.5048725146627966 0.1323568559135961 1.0 0.4089778093888778 2 P30626 1 +Purine ribonucleoside metabolic process 0.663327747154775 1.503151581695385 0.1327999599236766 1.0 0.4097781067327529 8 Q13126,O60725 2 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.6623166735971651 1.5023160514848937 0.1330155051443304 1.0 0.4097808731646194 7 Q9NUD5,O75179,Q07021,O43657 4 +Microtubule anchoring at centrosome 0.6548042704626312 1.5015817187150118 0.1332051675614161 1.0 0.4100274151883434 2 Q15154 1 +Positive regulation of dna demethylation 0.6540925266903903 1.4982902457460323 0.1340578572479764 1.0 0.4117909071160576 2 Q93009 1 +Bradykinin catabolic process 0.6572977173561344 1.497330404517909 0.1343073072976561 1.0 0.4120339063268739 4 Q99829 1 +Process utilizing autophagic mechanism 0.3491539277361967 1.4952602999277882 0.1348465217646073 1.0 0.4129470850567183 137 P12235,P50851,Q9NZJ7,P21796,O14681,O15118,Q9Y487,P30536,O15269,Q8TEY7,Q93050,Q15042,Q96HY6,P52789,Q9Y5X3,P04792,P16615,P42858,Q9Y263,Q8NHS3,Q86UE4,O75844,P51809,Q6PKG0,Q07820,O15027,Q86VR2,P09601,Q96GC9,Q9Y679,Q92889 31 +Microtubule anchoring at microtubule organizing center 0.6550373798504865 1.4945111552000174 0.1350420684595739 1.0 0.4131603227985629 3 Q8TD16,Q15154 2 +Regulation of blood pressure 0.6636466576695963 1.4943259292313789 0.1350904511343889 1.0 0.4131603227985629 17 Q6P179,P42892,P42785,Q6RW13,Q9NZ08,P09601,Q9UIQ6,Q9Y5X3,P05023,P20020 10 +Regulation of histone phosphorylation 0.6556773231090314 1.4897763165215727 0.1362830603665603 1.0 0.4154044028585343 4 Q9ULX6 1 +Protein targeting to mitochondrion 0.6109715648363591 1.485518248188591 0.1374065931140224 1.0 0.4176237796467916 44 Q99595,Q9NS69,O60830,Q15388,P55786,O14925,Q5JRX3,Q3ZCQ8,Q8N4H5,O95831 10 +Carboxylic acid transport 0.6425148085523895 1.4760280458496593 0.1399363633942572 1.0 0.4212716079949681 32 P04083,P30825,Q9NZJ7,Q01650,Q9UJS0,Q9Y619,Q15041,Q9H2D1,Q9UBX3,P53985 10 +Ph reduction 0.6593929300771706 1.4737402365055956 0.1405515448714254 1.0 0.4221209193602951 12 Q8N511,Q9Y487 2 +Regulation of cardiac conduction 0.6521640239453482 1.4733859279793422 0.1406470025173993 1.0 0.4222075106360776 4 P20020,P16615 2 +Neutral lipid metabolic process 0.6574661618395831 1.4717728437478406 0.141082229218532 1.0 0.4223748698590959 9 Q92604,Q8N2K0,Q06124,Q8NCC3,Q96N66 5 +Inner mitochondrial membrane organization 0.658740978764414 1.4698181434965534 0.1416110138774695 1.0 0.4231263531841762 17 Q9H3K2,Q13505,Q5XKP0,Q9Y4W6,Q9NX63,O95202,Q9P0J0,Q9NVH1,Q53H12,O75431,Q6UXV4,Q9Y512,O60313 13 +Nuclear pore organization 0.6576025227668694 1.4650477939369833 0.14290787855803 1.0 0.4249681963501812 12 Q9NQC3 1 +Hypothalamus development 0.648085877638233 1.462200165109395 0.1436863664150263 1.0 0.4262830074775382 3 O14949 1 +Phosphatidylinositol dephosphorylation 0.6493806236100007 1.4603895365842303 0.1441830468331302 1.0 0.4269569942904421 4 Q9NTJ5,Q9Y217 2 +Negative regulation of amyloid fibril formation 0.6502465995052078 1.4570104297706048 0.1451135012254309 1.0 0.4289743112238074 5 P61758,O15212,Q99471 3 +Regulation of amyloid fibril formation 0.6502465995052078 1.4570104297706048 0.1451135012254309 1.0 0.4289743112238074 5 P61758,O15212,Q99471 3 +Cell volume homeostasis 0.6484358271952549 1.4559758621560333 0.1453992924070546 1.0 0.4289743112238074 4 P51790,Q4KMQ2 2 +Modification of postsynaptic structure 0.6513253925948126 1.4551094130104891 0.1456389736569971 1.0 0.4289743112238074 6 Q9UQB8,Q7L576 2 +Natural killer cell mediated immunity 0.6532122625066505 1.4550982066072853 0.1456420756053913 1.0 0.4289743112238074 8 P07437,P04439,P68371,P01889,P51809 5 +Protein k63 linked deubiquitination 0.6511849570615498 1.4454517128129158 0.1483310469150183 1.0 0.4351730760650328 8 Q8TEY7,P40818 2 +Endoplasmic reticulum to cytosol transport 0.6527801341556456 1.4436523157821697 0.1488368009416936 1.0 0.4356290650197099 11 Q8TCT9,Q9BUN8,Q9GZP9,Q96CS3 4 +Cardiac cell development 0.6520943499368996 1.442943375098483 0.1490364230649725 1.0 0.4356290650197099 10 O75844 1 +Macropinocytosis 0.6432894268422935 1.4398710508109511 0.1499038847515008 1.0 0.437007402990915 3 Q06481,Q9UKG1 2 +Negative regulation of vascular associated smooth muscle cell proliferation 0.6464451045293685 1.439170408657981 0.1501022472147324 1.0 0.437332386482648 5 P09601 1 +Negative regulation of receptor signaling pathway via stat 0.6428963816638353 1.4380400851272557 0.1504226809040036 1.0 0.4376623181307031 3 O14964 1 +Negative regulation of receptor signaling pathway via jak stat 0.6428963816638353 1.4380400851272557 0.1504226809040036 1.0 0.4376623181307031 3 O14964 1 +Cell motility involved in cerebral cortex radial glia guided migration 0.6409252669039233 1.4372816904564878 0.1506379692304063 1.0 0.4376858372366276 2 O94901 1 +Positive regulation of amyloid precursor protein biosynthetic process 0.6405693950178081 1.4356299039538851 0.1511076808117391 1.0 0.4384475152491475 2 Q96IZ0 1 +Axon ensheathment in central nervous system 0.6405693950177906 1.4356299039538032 0.1511076808117624 1.0 0.4384475152491475 2 P18074 1 +Activation of phospholipase d activity 0.6422214311142898 1.434895472543402 0.1513168860534164 1.0 0.4388535958446224 3 P18085,Q14344 2 +Transition metal ion homeostasis 0.6482987046912014 1.4304114131914871 0.1525989744740026 1.0 0.4415615074163262 22 O75880,O43819,Q8N511,P09601,Q9Y487,P30519 6 +Regulation of hydrolase activity 0.3389803790963168 1.4293135140199618 0.1529141435222702 1.0 0.442134206262289 152 P04083,Q9NZJ7,Q14C86,P61289,P62942,P36404,P49327,Q4VCS5,Q15041,Q15392,Q9BXK5,Q8IZ81,Q15042,Q96K76,Q9P0J0,O95831,Q96HY6,Q14155,P30086,Q9NR28,Q96A26,P42858,Q15418,Q9Y263,Q96JB5,P51812,Q15363,Q66K14,P04080,P31751,P16435 31 +Ventricular system development 0.6477794049505787 1.4292359309710534 0.1529364336637111 1.0 0.442134206262289 8 Q96N66 1 +Proteolysis 0.3181372458492247 1.4289759574880598 0.1530111438456836 1.0 0.4421484808709972 340 P67812,P52888,Q9NZJ7,P60900,P42785,P61289,Q9UIQ6,P49327,O76024,Q9UHG3,P36551,Q15041,Q9BUN8,Q15392,O43765,Q9UBU6,Q9BXK5,Q8TEY7,Q9NY33,P55786,Q9Y4W6,P28074,Q9BT78,Q16740,Q96K76,Q9P0J0,Q8IXB1,O95831,Q96HY6,P40818,Q96CS3,P28072,Q9NZ08,P30086,O43292,Q9NR28,P49755,Q4ZIN3,Q96A26,Q15418,Q96A33,Q9Y263,Q96JB5,Q15005,Q99829,Q96FZ2,Q96KC8,Q8TCT9,Q92896,P51812,Q9NXR7,Q99436,O75844,P46379,P49721,Q96RU2,P27824,Q92769,Q9UJX4,P42892,Q13217,P09960,P04080,Q9GZP9,Q5JRX3,P38159,Q15369,Q96PU5,Q9H000,Q96J02,Q9BYT8,Q96FW1,Q9Y679,P16435 74 +Protein insertion into membrane 0.6478029492188861 1.427845410228651 0.1533363590911043 1.0 0.4422815236960983 22 Q9NS69,Q96A33,Q9P0J0,Q53H12,Q15629,Q9Y512,O43765,Q15070,P46379 9 +Positive regulation of t cell mediated immunity 0.6439294744275732 1.427355448067683 0.1534774656484328 1.0 0.4422999996874869 5 Q9NUQ9,P01889 2 +Cellular component disassembly involved in execution phase of apoptosis 0.6437387965597621 1.426459610550873 0.1537357174766129 1.0 0.4422999996874869 5 O95831 1 +Calcium ion regulated exocytosis 0.6470324416934768 1.4256773825649802 0.1539614880305264 1.0 0.4422999996874869 8 P16615,P51809 2 +Cellular transition metal ion homeostasis 0.6493875514482318 1.424350466603216 0.1543450453536274 1.0 0.4422999996874869 18 O75880,O43819,Q8N511,P09601,Q9Y487 5 +Membrane protein proteolysis 0.6486090417371329 1.423473237447714 0.1545990149224689 1.0 0.4426994837612679 11 P38159,Q9NZ08,Q16740,Q8TCT9 4 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.6490370507801833 1.4218226698590062 0.1550777367364011 1.0 0.4427948280727751 13 O95881,O76024,Q8IXB1,O95831,O60313,P46379 6 +Cellular response to dexamethasone stimulus 0.6438990130059432 1.4200952836176453 0.1555799431758637 1.0 0.4437039153489868 6 Q9H7B4 1 +Lipid metabolic process 0.3266599268105982 1.4140190298668882 0.1573563151224497 1.0 0.4461597176424894 237 P04083,Q9P035,Q9Y217,P07099,Q9NZJ7,Q9NPH0,Q06136,Q8N8N7,O60678,O15118,Q9BQE5,P49327,P21964,P23786,Q709F0,Q99805,Q9BWD1,Q15392,Q92947,P30536,O15228,Q9BZF3,O15269,Q8N2A8,Q86UY6,Q8NCC3,Q8NF37,Q9H7Z7,Q9NZ01,P06576,P38435,Q9BZF1,O43292,P49356,P53985,Q16850,P51648,Q06124,O75874,Q96N66,P11802,Q9NTJ5,Q8NBN7,Q9Y263,O15254,Q99829,P48449,O75844,Q9BY49,Q15067,O00116,P53396,Q9BT22,O95470,Q15800,P16435,P35790,Q15120,O76054,Q8NBX0,Q9Y6K0,P37268,P31751,Q96G23,Q14534,Q8N4Q0,Q99943 67 +Calcium ion export 0.637220106148189 1.4115782148144589 0.1580741906695828 1.0 0.4475943459665534 3 P20020 1 +Atp transport 0.6418504007039979 1.4104252985298036 0.1584141396792038 1.0 0.4481564299763905 6 P12236,P12235,Q6NUK1 3 +Acute inflammatory response 0.6401461380162501 1.409573107402082 0.1586657724160607 1.0 0.448251550225718 5 P42785,Q9BQE5 2 +Gpi anchor metabolic process 0.6400863410930171 1.409291925587667 0.1587488653882549 1.0 0.448251550225718 5 Q92643,O43292,Q96S52 3 +Positive regulation of amino acid transport 0.6383672579336466 1.408874853529335 0.1588721763937135 1.0 0.448251550225718 4 Q15041 1 +Phosphatidylcholine metabolic process 0.645315570469354 1.4075254291307768 0.1592716422566127 1.0 0.4491786368403003 11 Q8WTV0,Q8NCC3,Q96N66,Q8NF37,P35790,Q9Y6K0 6 +Establishment of protein localization to membrane 0.465993521389244 1.4068191977449265 0.1594810084067461 1.0 0.4495690170256007 71 Q9NS69,O60725,O15118,Q9HD20,P43307,Q15041,O43765,Q15042,Q9P0J0,Q15070,Q9UGP8,Q96A33,P40855,Q15629,P46379,O15027,Q9Y4C2,Q53H12,P31751,Q9Y512 20 +Positive regulation of neuron differentiation 0.6428755110206316 1.4058621012274346 0.1597650770509981 1.0 0.4501695390272012 8 Q8WUJ1 1 +L glutamate transmembrane transport 0.6388353283635171 1.403408438884105 0.1604950779691552 1.0 0.4516183475000359 5 Q9UJS0 1 +Generation of precursor metabolites and energy 0.3375751308709982 1.4018764313758676 0.1609521495875256 1.0 0.4521071684114141 161 P13073,P12235,O43676,O43819,P36404,P03886,P56134,P14406,O75964,P00403,Q9BRR6,P24539,P13807,Q9P0J0,P52789,Q13423,Q15070,Q7KZN9,P47985,O75874,O96000,Q9UDW1,Q9UJS0,P46976,Q9Y6M9,O14949,Q15067,O43175,O75306,P48735,P31751,P16435 32 +Fatty acid transmembrane transport 0.6390366408969232 1.397136216694246 0.1623726127589675 1.0 0.4539080911877945 6 O43772,P23786 2 +Neurotrophin signaling pathway 0.6369378817284546 1.3944816481697004 0.1631722075147306 1.0 0.4544945547223323 5 Q06124 1 +Genitalia development 0.636418544271889 1.3920377089944642 0.1639109792930178 1.0 0.4554462524052081 5 Q15392 1 +Negative regulation of cholesterol metabolic process 0.6309608540925231 1.390979259821456 0.1642317160873565 1.0 0.4554462524052081 2 O75477 1 +Negative regulation of alcohol biosynthetic process 0.6309608540925231 1.390979259821456 0.1642317160873565 1.0 0.4554462524052081 2 O75477 1 +Response to dexamethasone 0.6405602945499911 1.3908399155413562 0.1642739761127738 1.0 0.4554462524052081 9 Q9H7B4,P40818 2 +Crd mediated mrna stabilization 0.6403660142588822 1.3899079587320649 0.1645568285420275 1.0 0.4554462524052081 9 O60506,Q9H074,P67809 3 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.640366014258882 1.3899079587320635 0.164556828542028 1.0 0.4554462524052081 9 O60506,Q9H074,P67809 3 +Chromosome attachment to the nuclear envelope 0.6306049822064138 1.3893236870392374 0.1647343441780102 1.0 0.4554462524052081 2 O94901 1 +Ventricular cardiac muscle cell development 0.6306049822064022 1.3893236870391834 0.1647343441780266 1.0 0.4554462524052081 2 P06493 1 +Ventricular cardiac muscle cell differentiation 0.6306049822064022 1.3893236870391834 0.1647343441780266 1.0 0.4554462524052081 2 P06493 1 +Cellular response to oxygen levels 0.6285048974640053 1.3874545521133976 0.1653032003364334 1.0 0.4554462524052081 31 P55786,O75306,Q96A26,Q9Y4P3,Q8N511,P09601,Q15120,O95831,Q9Y487 9 +Establishment of protein localization 0.314156448460315 1.3858391991747423 0.1657960098506432 1.0 0.4556154876077737 467 Q99595,Q9NS69,O60830,O60725,P18031,O14964,A6NIH7,Q9UKG1,Q9HD20,P33176,Q8N4H5,P43307,Q9Y282,P55786,Q13432,O95831,Q9P2W9,Q16850,Q9Y5M8,Q96L92,Q9H7B4,Q15629,P46379,Q9BTX1,Q32P28,Q96GC9,P04083,O43865,O43823,P53992,Q8NFH4,Q96CS3,P04792,O15260,Q15070,Q15388,Q06124,O14925,Q96A33,Q15005,Q96KC8,Q8TCT9,Q07820,O15027,Q5JRX3,Q3ZCQ8,P55735,Q9Y3B3,P31751,P50402,Q9BUN8,P30536,O95070,Q9BW83,Q9Y5X3,P53985,Q13555,Q13190,Q9UGP8,Q14168,Q12907,P40855,Q8N1F7,P51809,Q15363,Q8TB36,Q9Y4C2,Q9GZP9,Q969T9,Q9Y679,Q9Y2T2,Q14C86,O96028,O15118,P48643,Q15041,O43765,Q9Y678,Q96PC5,Q15042,Q9P0J0,P52789,Q8N5M9,P49755,Q9Y3A6,O75312,Q7Z4Q2,Q8TD16,P27824,Q9HCU5,Q9BVK6,O95376,Q8IUD2,Q53H12,Q12769,Q9Y512,Q9NPA0 97 +Amino acid transport 0.6410463101837895 1.3839477819976227 0.166374444428105 1.0 0.4570068722760734 19 Q9UJS0,Q9Y619,Q15041,P30825,Q6P4A7,Q01650 6 +Negative regulation of steroid metabolic process 0.6311854752581035 1.383408071680024 0.1665397769785066 1.0 0.4571887871414713 3 P05023,O75477 2 +Ribonucleoside metabolic process 0.6389314727170864 1.383025298987388 0.1666571087733626 1.0 0.4571887871414713 9 Q13126,O60725 2 +Regulation of autophagy of mitochondrion 0.6406877995204306 1.3809156178183306 0.1673049073130532 1.0 0.4580149060978897 13 P42858,P21796,P30536 3 +Oxidative phosphorylation 0.5549358216729584 1.377520773582 0.1683512966846814 1.0 0.4582618735220573 54 P13073,O43676,P03886,P36542,P56134,P14406,P00403,O75964,Q9H3K2,P24539,P06576,P56385,Q7KZN9,P47985,O96000,Q9UDW1,P15954,Q9Y6M9,O95168,O14949,O75306,Q9Y375 22 +Nucleotide excision repair dna incision 0.6316704292408255 1.3774861334957422 0.1683619990239302 1.0 0.4582618735220573 4 P18074,Q92889 2 +Localization within membrane 0.335630612719292 1.3754839042414142 0.1689814724220084 1.0 0.4583482425157277 152 Q9NS69,O00264,O60725,Q9NZJ7,O14964,Q9UKG1,O15118,Q9HD20,P43307,Q99805,Q15041,O43765,Q15042,Q9P0J0,Q15070,Q96S97,Q96A33,Q9UGP8,Q96L92,Q14168,P35613,P40855,Q15629,Q8NCW5,Q9HD45,P46379,Q9BTX1,Q15363,O15027,Q9Y4C2,Q53H12,O14976,P31751,Q9Y512,Q9NPA0 35 +Toll like receptor signaling pathway 0.6382763126292995 1.3709680040132817 0.170384930423884 1.0 0.4596816970313565 12 Q9NQC3,Q9NPR9 2 +Activin receptor signaling pathway 0.6280427850298482 1.368723526161345 0.1710857134451866 1.0 0.4609567032747227 3 P62942 1 +Regulation of activin receptor signaling pathway 0.6280427850298482 1.368723526161345 0.1710857134451866 1.0 0.4609567032747227 3 P62942 1 +Regulation of mrna export from nucleus 0.632718690577273 1.367267795458663 0.1715413821017297 1.0 0.4614257061705627 6 Q9ULX6,Q08J23 2 +Regulation of keratinocyte migration 0.6294857822985511 1.3672369608756705 0.1715510436701666 1.0 0.4614257061705627 4 P42345,Q15555 2 +Keratinocyte migration 0.6294857822985511 1.3672369608756705 0.1715510436701666 1.0 0.4614257061705627 4 P42345,Q15555 2 +Regulation of cellular response to stress 0.3390266694758326 1.3659269911266851 0.1719618799890867 1.0 0.462138436594929 140 P18031,Q15233,O96028,P61160,Q7L7X3,P49327,O76024,P57088,O43765,P61978,P16989,Q96K76,Q99543,Q96HY6,P04792,Q9BPX6,O60313,P51116,O43813,Q4ZIN3,P51114,Q9NXR7,O75844,P46379,P67809,Q02750,Q15363,Q07820,O95881,P35637,Q96FW1,Q96J02,Q96G23,Q92889,Q53EL6 35 +Regulation of response to external stimulus 0.3478207253752141 1.365286685560759 0.1721629620630389 1.0 0.4624580708916707 117 P04083,Q07021,Q9UMX5,P18031,P60900,Q15233,Q9UKG1,P01889,Q9NUQ9,Q8N2K0,O43657,Q8IZ81,Q96PK6,O75179,Q9NZ08,P04792,Q9NUD5,Q9BVA1,Q06124,P04439,Q9Y3Z3,P80303,O14936,Q4KMQ2,O75844,P51809,Q02750,Q9H000,Q96J02,Q96G23,Q53EL6 31 +T cell mediated cytotoxicity 0.6321288738583968 1.364477442720817 0.1724173489261431 1.0 0.4625777900698429 6 Q9NUQ9,P01889 2 +Negative regulation of protein metabolic process 0.3200832856155718 1.3591716648638883 0.1740921978734955 1.0 0.4629789312289243 255 Q969T7,P18031,Q9NQC3,Q01105,P62942,O60506,O60678,O95197,Q15041,Q12972,O95071,Q15392,O43765,P30536,O95684,Q15750,P31483,Q14011,Q9Y287,Q5JVF3,Q96K76,O75718,Q8IXB1,Q9BWF3,Q96HY6,P61758,P04792,P00374,P30086,P49755,Q5PRF9,Q8IXJ6,Q16850,P51116,Q92990,Q9BPZ3,Q9NQT4,Q96S97,Q15418,Q9Y263,P19474,Q96JB5,P51114,Q14103,Q9H7B4,Q96KC8,Q92896,P51812,Q6PKG0,P46379,P67809,Q15363,Q92769,Q13217,P04080,Q96B26,Q9H074,Q32P28,Q96FW1,O15212,Q9Y6M1,P16435,Q53EL6,Q92945 64 +Positive regulation of amine transport 0.6293993667281954 1.358980449699048 0.1741527838887702 1.0 0.4629789312289243 5 Q15041 1 +Triglyceride metabolic process 0.6313531727508628 1.3555698685926116 0.1752360642573598 1.0 0.4646321921334264 7 Q92604,Q06124,Q96N66 3 +Organic anion transport 0.5956237975802425 1.3505809373979825 0.1768297105925607 1.0 0.4651597658883591 42 Q14728,P12235,P04083,P30825,Q9NZJ7,Q01650,Q9HC21,Q9UJS0,Q8TB61,Q9Y619,Q15041,Q9H2D1,Q9UBX3,P53985 14 +Caveolin mediated endocytosis 0.62510487617844 1.3466711466221142 0.178086168943838 1.0 0.4673010569760254 4 Q13432 1 +Chemokine c c motif ligand 5 production 0.6206405693950134 1.342919829882365 0.1792979346748764 1.0 0.4698970273096327 2 O00571 1 +Regulation of establishment or maintenance of cell polarity 0.6271692103046398 1.3410015617231004 0.1799199455478164 1.0 0.4705977773829481 6 Q9NUQ9 1 +Neural retina development 0.6267683258665906 1.339103109596903 0.1805371083181501 1.0 0.4712835251821994 6 P20020,Q8NBN7 2 +Regulation of endoplasmic reticulum unfolded protein response 0.6274752912733826 1.3371205974464888 0.1811832748067543 1.0 0.4724931738479022 7 P18031,O76024,Q96HY6 3 +Negative regulation of defense response to virus 0.6262877857295567 1.3368272614350554 0.181279028361708 1.0 0.4725484174118239 6 Q07021,Q96J02,Q92890,O43657 4 +Collagen fibril organization 0.6268070846828294 1.3339402842275048 0.1822234278786978 1.0 0.4744247586143419 7 Q96AY3,Q92791,P13674 3 +Progesterone receptor signaling pathway 0.6215162887760945 1.3298127759997949 0.1835799654380565 1.0 0.4769244881864729 4 Q969T9 1 +Regulation of production of small rna involved in gene silencing by rna 0.6242405073249465 1.327129233370589 0.1844659365533902 1.0 0.4786898607448133 6 O75844 1 +Adipose tissue development 0.6275707724404769 1.3246644823998437 0.1852824583895422 1.0 0.4802187888811981 10 O15173 1 +Cell growth 0.3496851703764126 1.323584679154395 0.1856410161824588 1.0 0.480472844983372 86 O95684,Q9NVI7,Q9NQC3,Q9GZP9,Q5BJF2,Q15418,Q7L576,O14681,Q96K76,Q9Y263,Q99829,Q96J02,P51812 13 +Regulation of defense response to virus 0.6288889301999028 1.3229852499688903 0.1858402830471164 1.0 0.480472844983372 13 Q8IZ81,O75844,Q96J02,O43657 4 +Regulation of alcohol biosynthetic process 0.6232675575997926 1.322519192536147 0.1859953226842217 1.0 0.480472844983372 6 Q13131,P16435,O76054 3 +Regulation of cholesterol biosynthetic process 0.6232675575997926 1.322519192536147 0.1859953226842217 1.0 0.480472844983372 6 Q13131,P16435,O76054 3 +Negative regulation of blood pressure 0.6198143278371404 1.3218138344039512 0.1862301504140953 1.0 0.480472844983372 4 P42785 1 +Cellular response to lipid 0.3729364985088828 1.3211781681188404 0.1864419639914962 1.0 0.480472844983372 83 P04083,O15118,P08670,P20020,P30536,O43823,Q9P0J0,O95831,Q96HY6,O15173,P40818,P11802,Q9Y263,Q14103,Q9H7B4,Q86UE4,Q8TB36,Q969T9,Q15120,Q86X55,Q53EL6 21 +Regulation of synaptic vesicle recycling 0.6213298472777811 1.3209226821717244 0.1865271458892108 1.0 0.4804969607723288 5 Q7L576 1 +Intracellular lipid transport 0.6257460836847771 1.3196733877363604 0.1869440888652573 1.0 0.4811798095609813 9 P23786 1 +Threonine catabolic process 0.6149466192170772 1.3163661477535078 0.1880511788403598 1.0 0.4822664185800729 2 O75600 1 +Sensory perception of light stimulus 0.6271874652875179 1.312982143349246 0.1891889653123466 1.0 0.4845959875441959 14 Q9ULX3,O43924,Q13432,Q92696,O60313 5 +Organic acid transport 0.5894153472990917 1.312455319360267 0.1893665521877181 1.0 0.4848548853388161 42 P04083,P30825,Q01650,O43772,P31751,Q9UJS0,Q6P4A7,P23786,Q9Y619,Q15041,Q9H2D1,Q9UBX3,P53985 13 +Cellular response to corticosteroid stimulus 0.6262055868107224 1.312010753648996 0.1895165062143746 1.0 0.485042851324916 12 P04083,O95831,Q9H7B4 3 +Deadenylation dependent decapping of nuclear transcribed mrna 0.6131672597864797 1.3080633036462246 0.1908518388227449 1.0 0.4870834082238157 2 Q9UIV1 1 +Head morphogenesis 0.6180655946107506 1.305513457869227 0.1917180676078858 1.0 0.4883126504904664 5 O95470,Q06124 2 +O glycan processing 0.6155699451972139 1.3018568572249156 0.1929653230265287 1.0 0.4910928722968322 4 Q10472,O43505 2 +Cellular ion homeostasis 0.393324691120868 1.2990912098610683 0.1939126293671473 1.0 0.4923879604099832 80 O75880,P16615,Q8IYU8,Q9Y4W6,Q93050,O43819,P42858,Q8N511,P09601,Q96A33,Q9HD20,Q8NEW0,O76024,Q96PU5,P62942,P20020,Q9BPX6,Q9Y487 18 +Embryonic hemopoiesis 0.6130508432923603 1.2985575723573546 0.1940958063916897 1.0 0.4923879604099832 3 Q03164 1 +Regulation of translation in response to endoplasmic reticulum stress 0.6147563818925117 1.2980301195004456 0.1942769852463532 1.0 0.4926503623473953 4 Q15363 1 +Negative regulation of exocytosis 0.6188010885852362 1.2958095945273522 0.1950410917262051 1.0 0.4934033526023799 7 P09601 1 +Regulation of ire1 mediated unfolded protein response 0.6156109977110886 1.2939215355981764 0.1956925249471064 1.0 0.4941820123817161 5 P18031,P57088,Q96HY6 3 +Negative regulation of anoikis 0.6119775324372083 1.29352800207784 0.1958285056536848 1.0 0.4941820123817161 3 Q07820 1 +Lipid biosynthetic process 0.3415712278878938 1.2924063898293705 0.1962164450120034 1.0 0.4941820123817161 122 P04083,Q9P035,Q9Y217,Q9NPH0,Q06136,O60678,P49327,Q99805,Q15392,P30536,O15228,Q9BZF3,O15269,Q8NF37,Q9H7Z7,Q9NZ01,O43292,Q16850,O75874,Q96N66,Q9NTJ5,P48449,Q9BY49,O00116,P53396,O95470,Q15800,P16435,P35790,O76054,Q8NBX0,Q9Y6K0,P37268,Q96G23,Q14534,Q99943 36 +Regulation of cell population proliferation 0.3303969917872947 1.2915692734562518 0.1965063506503872 1.0 0.4942320668971023 187 P04083,Q9NQC3,P55209,P43307,Q96DY7,Q15392,O95684,Q96HY6,P30825,O60443,O14936,P43490,O75844,P09601,P16435,Q32P28,Q96J02,P31751,Q96G23,Q14534,Q53EL6 21 +Fc receptor signaling pathway 0.6150355361590572 1.2912033447514657 0.1966331756106552 1.0 0.4942320668971023 5 Q06481,Q9UKG1 2 +Lipoprotein metabolic process 0.6210221798497015 1.28248069012465 0.1996740745006819 1.0 0.4971995391465634 14 Q9BQE5,Q9NUJ1 2 +Intraciliary transport 0.6131381676135749 1.2822397243799502 0.1997585650413682 1.0 0.4971995391465634 5 A0AVF1,Q7Z4L5,Q9BW83 3 +Glycine metabolic process 0.6152687712391143 1.278972237420722 0.2009068325225858 1.0 0.4986864855838723 7 P23378,O43175 2 +Regulation of b cell apoptotic process 0.6060498220640518 1.2748320919569518 0.2023686791531145 1.0 0.5013331977299791 2 P14174 1 +Negative regulation of b cell apoptotic process 0.6060498220640518 1.2748320919569518 0.2023686791531145 1.0 0.5013331977299791 2 P14174 1 +Smad protein signal transduction 0.6145244895636983 1.2702842401809835 0.2039833998885014 1.0 0.5043475634387178 8 Q8N1F7,P08670,Q9UIQ6 3 +Mitophagy 0.6172258583741104 1.2680772768839947 0.2047703553454301 1.0 0.5057013802899417 12 P12235,P21796,P50851 3 +Negative regulation of lymphocyte apoptotic process 0.6062655749376982 1.2667504902254414 0.2052445201581321 1.0 0.5061462718149452 3 P14174,P78540 2 +Negative regulation of leukocyte apoptotic process 0.6062655749376982 1.2667504902254414 0.2052445201581321 1.0 0.5061462718149452 3 P14174,P78540 2 +Cytosolic calcium ion transport 0.6172368445989306 1.2663027020989206 0.2054047299301573 1.0 0.5061462718149452 21 P16615,Q8IYU8,P62942,P21796,P42858,P20020,Q9BPX6 7 +Negative regulation of protein k63 linked ubiquitination 0.6079843135645738 1.2661613544438806 0.2054553202053224 1.0 0.5061462718149452 4 Q96FW1,Q9Y263 2 +Negative regulation of protein polyubiquitination 0.6079843135645738 1.2661613544438806 0.2054553202053224 1.0 0.5061462718149452 4 Q96FW1,Q9Y263 2 +Regulation of rig i signaling pathway 0.6113522070665904 1.2660097167358857 0.2055096035000558 1.0 0.5061462718149452 6 O75179,Q9NUD5,Q14671,Q07021 4 +Pore complex assembly 0.6176072036891059 1.2655748954347714 0.2056653187028536 1.0 0.5063329932478569 14 Q9NQC3,Q9BTX1,Q4KMQ2 3 +Positive regulation of intracellular signal transduction 0.3409260248687906 1.2650604173337163 0.2058496707554817 1.0 0.5063933864819441 116 Q9Y4R8,Q9UMX5,Q07021,P18031,Q9NQC3,P62942,Q7L7X3,Q15750,O43657,O00429,Q5JVF3,O75179,Q9NUD5,Q9BZF1,O60443,Q06124,Q96AG4,Q01085,P19474,Q96JB5,P05771,Q8TB61,Q99829,Q86UE4,Q02750,Q07820,P09601,P55735,Q53EL6 29 +Atp synthesis coupled electron transport 0.5988215295300342 1.2635527765704002 0.2063905923914739 1.0 0.5071941256889028 35 P00403,Q7KZN9,P47985,O14949,O43676,O75306,O96000,P03886,Q9UDW1,Q9Y6M9 10 +Cellular response to lipoprotein particle stimulus 0.6050615262842631 1.2611037994821193 0.2072714518987861 1.0 0.5083965025230864 3 O15118 1 +Establishment of protein localization to organelle 0.3279224628792561 1.2428927144815345 0.2139073707652607 1.0 0.5181907746605824 169 Q99595,Q9NS69,O60830,O14964,Q9UKG1,P48643,Q8N4H5,Q9UFC0,O43765,P30536,P55786,Q15042,Q9P0J0,O95831,P52789,Q15070,Q15388,O14925,Q9Y5M8,Q9UGP8,Q15005,O75312,P40855,Q15629,Q7Z4Q2,Q8N1F7,P46379,Q8TB36,O95376,Q5JRX3,Q3ZCQ8,P55735,Q53H12,Q9Y512,Q9Y2T2 35 +Protein hydroxylation 0.6115148685982271 1.237485620866329 0.2159068493540674 1.0 0.5212196968978002 13 Q96AY3,Q32P28,Q92791,P13674 4 +Leukocyte mediated cytotoxicity 0.6104675388229485 1.2349815787156662 0.2168373600716964 1.0 0.5224060224015583 12 P07437,Q9NUQ9,P04439,P68371,P01889,P51809 6 +N terminal protein amino acid modification 0.6059338197421437 1.2344442950541683 0.2170373919657602 1.0 0.522521986911913 7 Q9BV86 1 +Positive regulation of ossification 0.6010217333204148 1.233372975171941 0.2174366428949812 1.0 0.522521986911913 4 Q4KMQ2,Q06124 2 +Regulation of proteolysis 0.3303060179738974 1.2302172960979758 0.218615744673704 1.0 0.5241649542176551 140 Q9NZJ7,P61289,P49327,Q15041,Q15392,O43765,Q9BXK5,Q96K76,Q9P0J0,O95831,Q96HY6,P30086,Q9NR28,P49755,Q4ZIN3,Q96A26,Q15418,Q96JB5,Q92896,Q96KC8,P51812,P46379,Q92769,P04080,Q9H000,Q96J02,P16435 27 +Negative regulation of jnk cascade 0.6017248614443867 1.2282828471827454 0.2193408077292908 1.0 0.5253051293201346 5 Q96J02 1 +Negative regulation of tyrosine phosphorylation of stat protein 0.5960854092526663 1.2282666482866176 0.2193468866205403 1.0 0.5253051293201346 2 Q8WXW3 1 +Mitochondrial electron transport nadh to ubiquinone 0.6091097193896758 1.2223608451255934 0.2215711992586582 1.0 0.5282772522656487 20 P03886,Q9Y6M9,O43676 3 +Negative regulation of cellular response to insulin stimulus 0.6021535249058031 1.222334024137045 0.2215813376238116 1.0 0.5282772522656487 6 P18031,Q13131,P05771,Q9HCD5 4 +Multicellular organism aging 0.605229192518204 1.220851084377536 0.2221424079345606 1.0 0.5292167064215454 9 O75844 1 +Phosphatidylcholine biosynthetic process 0.6030172834630313 1.2205252018975905 0.2222658418238738 1.0 0.5292832600368085 7 Q9Y6K0,Q8NF37 2 +Membrane lipid biosynthetic process 0.6087161202644702 1.2203363651001122 0.2223373896509364 1.0 0.5292832600368085 20 O15269,Q9P035,O95470,Q06136,Q8NBX0,Q96G23,O43292 7 +Protein ufmylation 0.596603030116799 1.2125557002626048 0.2252997346126339 1.0 0.5311627193185965 4 Q96HY6 1 +Positive regulation of mitochondrion organization 0.6073575133433786 1.211520827431614 0.2256958573560359 1.0 0.5314881635322184 18 Q8N2A8,P21796,Q96A26 3 +Regulation of neuron projection regeneration 0.5978416175809455 1.209913885781 0.2263119383842853 1.0 0.5322179412973407 5 Q96G23 1 +Dna methylation 0.6065558021340705 1.2080110474035122 0.2270430129996106 1.0 0.5322179412973407 16 Q03164,Q8N2A8,O75844 3 +Proteasomal protein catabolic process 0.3306082717617164 1.204250069558329 0.2284929388857532 1.0 0.5327944698186828 136 P60900,P61289,O76024,Q9BUN8,O43765,Q9UBU6,P28074,Q96HY6,Q96CS3,P28072,Q4ZIN3,Q9Y263,Q96A33,Q8TCT9,Q99436,P46379,P49721,Q9UJX4,Q9GZP9,Q96PU5,Q9H000,Q96J02,Q9Y679 23 +Tail anchored membrane protein insertion into er membrane 0.6007433400804342 1.204197641291372 0.2285131974370777 1.0 0.5327944698186828 8 O43765,P46379 2 +Multicellular organism reproduction 0.3399594311840731 1.204178351159263 0.2285206515649644 1.0 0.5327944698186828 106 Q9BTX1,Q15363,Q99417,Q8N2A8,P04083,Q06124,Q9BPZ3,O95470,Q08J23,Q8NB78,Q9BW83,Q9BQE5,O75718,O95067,P46379 15 +Histone h4 r3 methylation 0.5907473309608521 1.2033078944439142 0.2288571952433709 1.0 0.5333828783586765 2 O14744 1 +Protein localization to endoplasmic reticulum 0.5936259982532125 1.2021575423671638 0.2293024955959981 1.0 0.5340288712571447 32 Q9NQC3,Q9Y5M8,O15027,Q9UGP8,Q15005,Q96HY6,Q15629,O43765,O43292,P46379 10 +Dendrite extension 0.5951127654824814 1.1970036265702642 0.2313051412203242 1.0 0.5365229428672015 5 Q9Y263,Q7L576 2 +Regulation of apoptotic signaling pathway 0.3621864457856811 1.1958662832558349 0.2317487445518815 1.0 0.5371638203195788 83 P18031,Q15233,P61289,P49327,O76024,P45880,Q9H3K2,P61978,P30154,P16989,Q96K76,Q9P0J0,P04792,O60313,O60443,P42858,Q07820,O95881,P09601 19 +Ribonucleoprotein complex localization 0.5978015958086833 1.1956280425689083 0.2318417431539794 1.0 0.5371638203195788 7 Q9ULX6,Q08J23 2 +Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.5929642542851167 1.1954096027990788 0.2319270356384932 1.0 0.5371638203195788 4 O43657 1 +Long chain fatty acid transport 0.6016517695617136 1.1952092974874984 0.2320052668793888 1.0 0.5371638203195788 11 O43772,P04083,P23786 3 +Dna deamination 0.5927409262971397 1.1943572065825063 0.2323382688366932 1.0 0.5377383526727996 4 Q9NQT4 1 +Regulation of translation in response to stress 0.6013827222601942 1.1938979605172666 0.2325178854160823 1.0 0.5378279169285485 11 Q15363,P51812,Q15418 3 +Negative regulation of smooth muscle cell differentiation 0.5917879930956269 1.189866607874778 0.2340988247814355 1.0 0.5398414310916874 4 Q53EL6 1 +Multi organism reproductive process 0.3304138602006372 1.1877450000141574 0.2349338889831238 1.0 0.5413024016113245 134 Q9BTX1,Q99417,Q8N2A8,O95470,Q08J23,Q9UIQ6,Q8NB78,Q9BQE5,Q96GC9,P45880,P46379 11 +Positive regulation of wound healing 0.5960585592150565 1.1873066012014977 0.23510670523711 1.0 0.5413642159808344 7 P04083 1 +Cellular response to nutrient 0.59468561490106 1.1868579406210271 0.2352836598275023 1.0 0.5413916312007561 6 Q8TB36,P09601 2 +Methylation 0.3394241103656173 1.1827108434945428 0.2369237652318547 1.0 0.5434006159119191 93 Q03164,Q8N2A8,Q9BV86,O60725,Q08J23,Q8NB78,O75648,Q9H7B4,O75844 9 +Regulation of vascular endothelial growth factor receptor signaling pathway 0.5902206528046375 1.1824805217309065 0.2370150897848102 1.0 0.5434006159119191 4 P18031,O14964 2 +Regulation of dendritic cell differentiation 0.5881597325084883 1.1817882157640571 0.2372897448024757 1.0 0.5436388694191211 3 P01889 1 +Calcium ion transport 0.5304322569314346 1.1767286762468283 0.2393038183211711 1.0 0.5474614789535239 53 Q13555,P16615,Q8IYU8,Q9BPX6,P62942,P21796,P42858,O14936,O76024,Q4KMQ2,Q96GC9,O75844,P20020,P30536 14 +Regulation of bone mineralization 0.5907780428595493 1.176494142164577 0.2393974718736289 1.0 0.547478087067191 5 Q4KMQ2,O75844 2 +Positive regulation of oligodendrocyte differentiation 0.5879317967304015 1.171694134604581 0.241319878746778 1.0 0.5506820567584921 4 Q92769 1 +Chemical synaptic transmission postsynaptic 0.5937548513696157 1.1706666032438438 0.241732814245251 1.0 0.5510290805295525 8 Q9UQB8,Q14168 2 +Regulation of postsynaptic membrane potential 0.5937548513696157 1.1706666032438438 0.241732814245251 1.0 0.5510290805295525 8 Q9UQB8,Q14168 2 +Lipoprotein catabolic process 0.5871878520091381 1.1681882522716294 0.2427308380958917 1.0 0.552310707724835 4 Q9NUJ1 1 +Protein depalmitoylation 0.5871878520091381 1.1681882522716294 0.2427308380958917 1.0 0.552310707724835 4 Q9NUJ1 1 +Negative regulation of release of cytochrome c from mitochondria 0.5884928121347214 1.1656814501944193 0.243743262785459 1.0 0.5537474833811639 5 Q9H3K2,O60313 2 +Protein quality control for misfolded or incompletely synthesized proteins 0.5955655528094695 1.1655431811710488 0.2437991918310631 1.0 0.5537474833811639 11 Q9BUN8,Q16740,P46379 3 +Protein k48 linked deubiquitination 0.5944396983041127 1.1641853096789707 0.2443489222402821 1.0 0.5543174464043166 10 Q8TEY7,P40818 2 +Isocitrate metabolic process 0.5873972165917777 1.1604976509005134 0.2458462496126738 1.0 0.5560055973574284 5 P48735 1 +Positive regulation of protein kinase b signaling 0.5942686417861509 1.1499148578983982 0.2501789406845427 1.0 0.5625177430354613 14 Q9NQC3,Q99829 2 +Ether metabolic process 0.5891324597286063 1.1484875771750904 0.250767338500107 1.0 0.5625177430354613 8 P49327,O00116,P07099 3 +Response to misfolded protein 0.5888825388009986 1.1472884693067575 0.2512624179852207 1.0 0.5634288544841981 8 Q9BUN8,P46379 2 +Protein import 0.3791995196532859 1.1453468984243496 0.2520654858609934 1.0 0.5644546445104577 80 Q99595,Q9NS69,O60830,Q15388,O14925,Q3ZCQ8,O95831 7 +Vascular endothelial growth factor receptor signaling pathway 0.5870171422288989 1.14414076265685 0.2525652650580718 1.0 0.5649509652922702 7 P18031,O14964,P04792 3 +Regulation of anion transport 0.5917859633708223 1.1434299996758526 0.2528601027974255 1.0 0.5653604209754949 12 O43865,Q9Y4C2,Q15041 3 +Histone h4 k16 acetylation 0.5880188383613123 1.1431445499077562 0.252978580149674 1.0 0.5653604209754949 8 O75844 1 +Nuclear transcribed mrna catabolic process exonucleolytic 3 5 0.5889260819429052 1.1422290287141297 0.2533588326940457 1.0 0.5653604209754949 9 Q96B26,Q9NQT4,Q6PGP7 3 +Regulation of biomineralization 0.584970699420159 1.1407024316213463 0.253993774331525 1.0 0.566078473774044 6 Q4KMQ2,O75844 2 +Protein exit from endoplasmic reticulum 0.5932125444915243 1.14056270264829 0.2540519456230679 1.0 0.566078473774044 20 Q9HCU5,O15027,Q9GZP9,P55735,Q96CS3,Q8TCT9,Q9BUN8,Q9Y679,O15260 9 +Lipid droplet organization 0.5882738524568412 1.139083717312116 0.254668238159488 1.0 0.566853749637048 9 Q15042,Q96CS3,Q9Y679,Q14534,O96017 5 +Positive regulation of interleukin 2 production 0.5844475679042773 1.1382173191061535 0.2550297485486867 1.0 0.5669349104551817 6 P04083,Q92990 2 +Regulation of glycoprotein metabolic process 0.5874934175731815 1.1353202538304064 0.2562411590246367 1.0 0.5683299879339297 9 Q96IZ0,Q9Y287,Q99805 3 +Pyridine containing compound metabolic process 0.5849372238518968 1.1342119003235132 0.256705673398788 1.0 0.5683299879339297 7 P43490 1 +Negative regulation of dna binding 0.5870812817949682 1.1333328771905369 0.2570744901665973 1.0 0.5688132137519998 9 Q92769,Q99829,P09601 3 +Excretion 0.5831550615219853 1.1320775837015076 0.2576018181827311 1.0 0.5693835792898385 6 P09601,Q9Y5X3 2 +U4 snrna 3 end processing 0.5842670087424142 1.1310127087723645 0.2580497424112948 1.0 0.5699760256745819 7 Q96B26,Q9NQT4 2 +Positive regulation of map kinase activity 0.58209169181438 1.1270266177367163 0.2597312271725667 1.0 0.5714988842335261 6 P18031 1 +Pyridine nucleotide metabolic process 0.5759704751510565 1.1153353099310437 0.2647067595605961 1.0 0.5777288977593948 4 P43490 1 +Pattern recognition receptor signaling pathway 0.5849059221324588 1.1133390675538437 0.2655628336139695 1.0 0.5777288977593948 26 O43657,Q9NQC3,Q9NPR9,O75179,Q96J02,P51812 6 +Mitochondrial genome maintenance 0.5802020866077241 1.1116120604106752 0.2663049847805507 1.0 0.5777288977593948 7 Q9BQP7,O60313 2 +Regulation of phospholipase a2 activity 0.5749768494638688 1.1106552947396695 0.2667167519781066 1.0 0.5777288977593948 4 P04083 1 +Sphingolipid biosynthetic process 0.5855888759016856 1.1068915710356029 0.2683408105932576 1.0 0.5777288977593948 14 O15269,Q9P035,O95470,Q06136,Q96G23 5 +Cytoplasmic pattern recognition receptor signaling pathway 0.5853561522373131 1.1057383033099617 0.2688398060455876 1.0 0.5777288977593948 14 Q14671,Q07021,O43657,O75179,Q8ND56,Q96J02,Q9NUD5 7 +Cell migration involved in sprouting angiogenesis 0.5775861488583324 1.1056294777408502 0.2688869255269059 1.0 0.5777288977593948 6 P09601 1 +Regulation of amyloid beta clearance 0.5787296341310539 1.104585930518833 0.2693390502679482 1.0 0.5777288977593948 7 Q16850 1 +Regulation of receptor clustering 0.5693950177935871 1.103472982251303 0.2698218181720531 1.0 0.5777288977593948 2 Q15334 1 +Regulation of response to stress 0.3149640580692242 1.1007188877326488 0.2710190232163942 1.0 0.5777288977593948 222 P04083,Q07021,P18031,P60900,Q15233,Q9UKG1,O96028,P61160,Q7L7X3,P49327,O76024,P57088,P01889,O95071,O43765,P61978,O43657,Q8IZ81,P16989,Q96K76,Q96PK6,Q99543,Q96HY6,Q9NZ08,P04792,Q9BPX6,O60313,Q9NUD5,P51116,Q06124,P04439,O43813,Q9Y3Z3,Q4ZIN3,O14936,P51114,Q4KMQ2,Q9NXR7,O75844,P46379,P51809,P67809,Q02750,Q15363,Q07820,O95881,P35637,Q96FW1,Q9H000,Q96J02,Q96G23,Q92889,Q53EL6 53 +Response to nicotine 0.5725206265324467 1.099088192086653 0.2717295998152305 1.0 0.5778061848451911 4 P09601 1 +Fc epsilon receptor signaling pathway 0.5676156583629821 1.095159044508626 0.2734469648549791 1.0 0.5795429485906363 2 P19174 1 +B cell apoptotic process 0.5695977216091113 1.094678786945949 0.2736573852650412 1.0 0.5796197262952236 3 P14174,Q9Y3T9 2 +Regulation of cysteine type endopeptidase activity 0.5590594299559691 1.0946588497829677 0.2736661229407147 1.0 0.5796197262952236 40 Q9NR28,Q9BXK5,Q9NZJ7,Q96A26,Q15418,P16435,P49327,Q96K76,O95831,Q15041,P51812,Q15392 12 +Response to abiotic stimulus 0.3187684247361029 1.090485364036308 0.2754993970163113 1.0 0.5811716640786834 187 P04083,Q8N511,P49327,Q70UQ0,P20020,Q9Y487,P30519,P30536,P00403,P55786,Q14011,Q6RW13,P16989,Q13432,Q96K76,Q99543,O95831,Q9BPX6,Q96A26,P42858,Q8NBN7,Q9Y4P3,Q9NXR7,O75844,Q96RU2,O75306,Q13217,P09601,Q7L576,Q15120,P31751 31 +Regulation of morphogenesis of an epithelium 0.5665480427046188 1.0901714798380633 0.2756376139918299 1.0 0.5812697370603083 2 Q99623 1 +Negative regulation of cysteine type endopeptidase activity 0.5831366323517824 1.0885014312856496 0.2763738050615449 1.0 0.5822409583361072 18 Q96K76,P51812,Q15392,Q15418 4 +Cellular macromolecule localization 0.3036377015905361 1.0843164884951937 0.2782244970159309 1.0 0.5849100733035726 481 Q99595,Q9NS69,O60830,O60725,P50851,Q9NQC3,P18031,O14964,Q9UKG1,Q9HD20,P33176,Q8N4H5,Q9UFC0,P43307,O95071,Q9Y282,P55786,Q5JRA6,P31483,O00429,O15258,O95831,Q9P2W9,Q9Y5M8,Q96L92,Q15629,Q9HD45,P46379,Q9Y6C9,O00264,O43865,Q96DY7,P53992,Q7Z4L5,Q96HY6,Q96CS3,P04792,O15260,Q15070,O43292,Q15388,Q06124,O14925,Q96A33,O14936,Q15005,Q8TCT9,O15027,Q5JRX3,Q3ZCQ8,P55735,Q9Y3B3,P31751,P50402,Q99805,Q9BUN8,P30536,Q9BW83,Q9Y5X3,Q13190,Q9Y6X3,Q9UGP8,Q96JB5,Q14168,P40855,Q8N1F7,P67809,Q15363,Q8TB36,Q9Y4C2,Q9GZP9,Q96PU5,Q9Y679,Q9Y2T2,P36404,O15118,P48643,Q4VCS5,Q15041,O43765,Q9Y678,Q15042,Q9P0J0,P52789,Q9BZF1,Q99729,P49755,Q9Y3A6,Q96S97,P35613,O75312,Q7Z4Q2,Q8TD16,Q9HCU5,Q9BVK6,O95376,Q8NFQ8,Q53H12,O14976,Q9Y512,Q9NPA0 101 +Maternal process involved in female pregnancy 0.5768838411901063 1.0841772210496194 0.2782862294323007 1.0 0.5849100733035726 9 Q15363,Q9BQE5 2 +Walking behavior 0.5693531021851598 1.0841757846556834 0.2782868661843571 1.0 0.5849100733035726 4 O75844,O15118 2 +Positive regulation of autophagy 0.5800921053277486 1.0835191060190497 0.2785780750524245 1.0 0.5853280045116757 25 P12235,O15269,Q15042,P42858,P21796,P09601,Q86UE4 7 +Positive regulation of osteoblast differentiation 0.5667497330010638 1.0813245609769726 0.2795527657650778 1.0 0.586179061949446 3 Q96AC1,O00299 2 +Negative regulation of transcription regulatory region dna binding 0.5637010676156509 1.0768745860422209 0.2815362981773632 1.0 0.5880341204844928 2 P30626 1 +Erad pathway 0.5679720553160519 1.075427711627445 0.2821832804833688 1.0 0.5890178719110011 34 Q9UBU6,Q4ZIN3,Q9GZP9,Q96A33,O76024,Q8IXB1,Q96CS3,Q8TCT9,Q9BUN8,Q9Y679,O43765,P46379 12 +Positive regulation of blood vessel endothelial cell migration 0.575981585318046 1.0747312416814538 0.2824950721882144 1.0 0.5891424271397414 10 P04083,P09601 2 +Cellular response to leucine 0.5653257386970468 1.0746492982378986 0.2825317715129674 1.0 0.5891424271397414 3 Q9P2J5,P42345 2 +Response to leucine 0.5653257386970468 1.0746492982378986 0.2825317715129674 1.0 0.5891424271397414 3 Q9P2J5,P42345 2 +Cellular response to leucine starvation 0.5646137415450354 1.0713121726741697 0.2840290883260237 1.0 0.5910976462141255 3 Q9P2J5,P42345 2 +Establishment of protein localization to mitochondrial membrane 0.5768800452475841 1.070408280836063 0.2844355735361403 1.0 0.5917492545957063 12 Q9NS69,Q9P0J0,Q53H12,Q9Y512,Q15070 5 +Cytokine production 0.3301133174748861 1.068927875776508 0.2851021699458262 1.0 0.5923581806382626 89 P04083,Q07021,Q99943,Q9UKG1,P01889,P20020,P30536,Q9NUQ9,O43823,P31483,P04792,Q9NUD5,P49755,Q06124,P15260,Q92990,P04439,Q92769,P09601,Q8NCF5,Q96J02,Q9Y6M1,Q53EL6,Q01650 24 +Regulation of protein localization to centrosome 0.5615658362989273 1.0669054103351492 0.2860145514829781 1.0 0.5926992193419335 2 P37198 1 +Execution phase of apoptosis 0.5753622794289525 1.0629790556785397 0.2877914495423124 1.0 0.594243863066026 12 Q7L7X3,O95831 2 +Membrane protein ectodomain proteolysis 0.5718505530487217 1.0599341307869616 0.2891745668653327 1.0 0.5948102368543958 9 P38159,Q9NZ08,Q8TCT9 3 +Regulation of muscle organ development 0.570207269133579 1.057745001991409 0.2901717126586478 1.0 0.5964379315983949 8 Q13131,Q8IXJ6,P49454,P16989 4 +Sphingoid metabolic process 0.5651700959139293 1.0554069547022809 0.2912392435075892 1.0 0.5980502547335038 5 O15269 1 +Regulation of protein k63 linked ubiquitination 0.5649936441975061 1.0545737700522173 0.2916203053220383 1.0 0.598444907650828 5 Q96FW1,Q9Y263 2 +Regulation of mitochondrial fusion 0.5649105140626337 1.0541812478538846 0.2917999436920004 1.0 0.5986196967226309 5 Q8N2A8 1 +Hormone catabolic process 0.5596416496399607 1.0480185886337718 0.2946300426261679 1.0 0.6008489912331265 3 P42892 1 +Positive regulation of smooth muscle cell apoptotic process 0.5633025310610122 1.0465898344492393 0.2952887923915819 1.0 0.6016865200596317 5 O95140,Q53EL6 2 +Diencephalon development 0.5629785457793091 1.0450605420745125 0.2959949891557929 1.0 0.6020092152898907 5 O14949 1 +Fatty acid alpha oxidation 0.5585617657529349 1.04296218700716 0.2969658059904572 1.0 0.602584794288033 3 Q9UJ83,A1L0T0 2 +Positive regulation of execution phase of apoptosis 0.5605008685722241 1.0425355044165237 0.297163473516862 1.0 0.6027820871822651 4 Q8IXJ6,Q13625 2 +Positive regulation of organic acid transport 0.5641830723258944 1.0420407974082495 0.2973927645395884 1.0 0.6027820871822651 6 Q15041 1 +Regulation of rna export from nucleus 0.5676590676924662 1.03975978960052 0.2984515149145941 1.0 0.6027820871822651 9 Q9ULX6,Q96ST2,Q08J23 3 +Mitochondrion localization 0.5708454065192778 1.0371307827079002 0.2996749108326524 1.0 0.6036363350116078 13 O75153,Q9BUK6 2 +Electron transport chain 0.4723163808543403 1.0368566292884185 0.2998026791431165 1.0 0.6037018041722051 62 P13073,O43676,O43819,P03886,P00403,Q9H3K2,Q9P0J0,P43304,Q7KZN9,P47985,O96000,P21912,Q9UDW1,P15954,Q9UJS0,Q9Y6M9,O14949,Q6FI81,O43175,O75306,P23378,P16435,Q9Y375 23 +Negative regulation of vascular endothelial growth factor receptor signaling pathway 0.5569151508535218 1.0352542209270814 0.3005502030114293 1.0 0.6045060527576094 3 P18031 1 +Regulation of phospholipid biosynthetic process 0.5605855210152619 1.0337678130522538 0.3012447222045167 1.0 0.6048955898349563 5 Q8NF37 1 +Calcium mediated signaling 0.5712003761770326 1.032926278169293 0.3016384001024854 1.0 0.6052826287047024 15 P16615,O75844 2 +Regulation of cellular amide metabolic process 0.3153966977364507 1.032597960808782 0.3017920828740676 1.0 0.6053138171997576 174 P23588,Q969T7,Q9NQC3,O60506,Q567V2,P55010,O95197,P08670,Q9Y2R0,Q14011,P16989,P04792,P49755,P51116,P15260,Q9BPZ3,Q9NQT4,Q15418,Q14103,Q07666,P51114,Q96KC8,P51812,Q6PKG0,P67809,Q15363,Q13217,Q7L576,Q71RC2,Q96B26,Q15120,Q9Y6M1,P31751,Q9H074,Q92945 35 +Odontogenesis of dentin containing tooth 0.5610126163169782 1.0270194343282408 0.3044113129722903 1.0 0.6082191214192586 6 P35613,Q92769 2 +Positive regulation of vascular associated smooth muscle cell apoptotic process 0.5551398545798943 1.0269468598139329 0.3044454873192186 1.0 0.6082191214192586 3 Q53EL6 1 +Regulation of lymphocyte apoptotic process 0.5586034912718126 1.024418771287187 0.3056375194651162 1.0 0.609639584781379 5 P14174,P17931,P78540,Q9Y3T9 4 +Glial cell migration 0.5668160534830036 1.0211805968287977 0.3071688834059678 1.0 0.6099502129319283 12 Q9NQC3,Q96G23,Q96N66 3 +Negative regulation of muscle cell differentiation 0.5628422783892296 1.0165954583297296 0.3093459156353417 1.0 0.6099502129319283 9 O75179,Q53EL6 2 +Exonucleolytic catabolism of deadenylated mrna 0.5639266451834463 1.0164114052269837 0.3094335167175503 1.0 0.6099502129319283 10 Q9NQT4,Q969T7 2 +Insulin receptor signaling pathway 0.5679845754238908 1.0162146326006878 0.3095271898541334 1.0 0.6099502129319283 24 Q13131,P11802,Q9HCD5,Q06124,Q92572,O14654,Q9UQB8,P18031,Q9UKG1,P05771,P43490,Q9Y5X3,P31751,Q9BZF1 14 +Positive regulation of cellular response to insulin stimulus 0.5586815094203113 1.0159813016365085 0.3096382907767336 1.0 0.6099502129319283 6 Q06124,Q9Y5X3 2 +L serine transport 0.5501779359430581 1.0138020130224852 0.3106772345712845 1.0 0.6102794902288375 2 Q15758 1 +Positive regulation of hexokinase activity 0.5498220640569367 1.012144669311255 0.3114688871094659 1.0 0.6106994004719866 2 P49792 1 +Regulation of hexokinase activity 0.5498220640569367 1.012144669311255 0.3114688871094659 1.0 0.6106994004719866 2 P49792 1 +Negative regulation of mitophagy 0.5498220640569316 1.0121446693112297 0.3114688871094782 1.0 0.6106994004719866 2 P04637 1 +Amino acid import 0.563043407413507 1.0121438077362777 0.3114692989979946 1.0 0.6106994004719866 10 P30825,Q01650 2 +Carbohydrate derivative transport 0.5657212074260383 1.0119424040704663 0.3115655928240386 1.0 0.6106994004719866 13 Q8WTV0,P12235,Q9NZJ7,Q9HC21,L0R6Q1,Q8TB61 6 +Positive regulation of cell population proliferation 0.3264114024635942 1.0114065223183055 0.3118219007514224 1.0 0.6110127968651095 101 O95684,P04083,Q9NQC3,P09601,P43490,P55209,P43307,P30825 8 +Dna dealkylation involved in dna repair 0.5515342514478154 1.0100850913007948 0.3124545243653047 1.0 0.6114960842813268 3 Q8N3C0 1 +Intrinsic apoptotic signaling pathway 0.4330981627065429 1.0068352734964177 0.3140139407200284 1.0 0.6140796037642826 69 Q9NR28,Q96RU2,Q07820,P09601,Q96K76,O76024,O95831,P45880,P04792,O60313,O60443,P46379 12 +Positive regulation of monooxygenase activity 0.5522691820102539 1.0038778960855812 0.3154374719775663 1.0 0.615679818056875 4 P16435,P00374 2 +Glycolytic fermentation 0.5500177999287955 1.002997837571706 0.3158619045994122 1.0 0.6160716803467144 3 P04637,O75746 2 +Fermentation 0.5500177999287955 1.002997837571706 0.3158619045994122 1.0 0.6160716803467144 3 P04637,O75746 2 +Sarcoplasmic reticulum calcium ion transport 0.556839846951618 1.0003045767632217 0.3171631329896762 1.0 0.6180647505904798 7 O75844 1 +Negative regulation of programmed necrotic cell death 0.5514586589309481 1.0000756711252188 0.3172738888544786 1.0 0.6180647505904798 4 P12235 1 +Negative regulation of necrotic cell death 0.5514586589309481 1.0000756711252188 0.3172738888544786 1.0 0.6180647505904798 4 P12235 1 +Transition metal ion transport 0.5603166161103629 0.9989742356130332 0.3178071723664704 1.0 0.6184562629828426 10 Q9HD20,O15173 2 +Response to progesterone 0.5547878837789288 0.9975581165457292 0.3184936793005009 1.0 0.6194887801495623 6 P30536 1 +Mast cell activation involved in immune response 0.5507402557755611 0.9967062808428422 0.3189071001199917 1.0 0.6199123599571741 4 P09601 1 +Mast cell activation 0.5507402557755611 0.9967062808428422 0.3189071001199917 1.0 0.6199123599571741 4 P09601 1 +Signal peptide processing 0.552673755416706 0.9964745988499596 0.3190196029195142 1.0 0.6199408842995896 5 P67812,Q15005 2 +Chondroitin sulfate proteoglycan biosynthetic process 0.545195729537363 0.9906134340853832 0.3218743753240414 1.0 0.6235762508188476 2 Q96L58 1 +Chondroitin sulfate biosynthetic process 0.545195729537363 0.9906134340853832 0.3218743753240414 1.0 0.6235762508188476 2 Q96L58 1 +Natural killer cell activation 0.555945774752247 0.9895335267890152 0.3224021747718211 1.0 0.6239191925636737 8 Q96L92,P46379 2 +Respiratory electron transport chain 0.5232004336074068 0.9876607972667876 0.3233188000526852 1.0 0.6239191925636737 47 P00403,Q7KZN9,P47985,O14949,O43676,O75306,O43819,O96000,P03886,Q9UDW1,Q9UJS0,Q9Y6M9 12 +Intestinal epithelial cell development 0.5441281138789952 0.9856486899909818 0.3243055362230569 1.0 0.6241956509948388 2 Q9NQ88 1 +Intestinal epithelial cell differentiation 0.5441281138789952 0.9856486899909818 0.3243055362230569 1.0 0.6241956509948388 2 Q9NQ88 1 +Regulation of t cell mediated immunity 0.5522448201500246 0.985535509395389 0.324361098110463 1.0 0.6241956509948388 6 Q9NUQ9,P01889 2 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.5593337867885833 0.9846470929536028 0.3247974490425012 1.0 0.6246559740765797 12 Q14671,Q07021,O43657,O75179,Q8ND56,Q9NUD5 6 +Intermediate filament bundle assembly 0.5437722419928758 0.983994129890974 0.3251183991477835 1.0 0.624893932483926 2 P58107 1 +Regulation of synaptic vesicle exocytosis 0.557135355050796 0.9836213759274262 0.3253017109218561 1.0 0.6250566834784118 10 P16615,Q15042,O14936,P35080,P05771 5 +Copii coated vesicle cargo loading 0.5555416675226654 0.981535936002446 0.3263285221055056 1.0 0.6256638465788131 9 Q15437,P53992,P55735,Q5JRA6 4 +3 utr mediated mrna destabilization 0.5509312089783642 0.9793287062139716 0.3274175910057506 1.0 0.6256638465788131 6 Q92945 1 +Regulation of lipopolysaccharide mediated signaling pathway 0.5427046263345169 0.9790315398533256 0.3275643958198699 1.0 0.6256638465788131 2 P14174 1 +Nephron morphogenesis 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Renal vesicle development 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Cell differentiation involved in metanephros development 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Metanephric renal vesicle morphogenesis 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Metanephric nephron morphogenesis 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Metanephric nephron development 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Regulation of epithelial cell differentiation involved in kidney development 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Nephron tubule epithelial cell differentiation 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Positive regulation of mesenchymal cell proliferation 0.5423487544483917 0.9773777129407804 0.3283821924761136 1.0 0.6256638465788131 2 P35222 1 +Mitochondrial atp synthesis coupled proton transport 0.5556041118783616 0.9762364106172546 0.3289473236697469 1.0 0.6263639393314862 10 O75964,P24539,P06576,P36542,P56134 5 +Cerebellar cortex development 0.5589926768313591 0.9753381630333552 0.3293925460852338 1.0 0.6266704281018445 14 Q02750,O14949,Q06124,P58546,Q15058,Q7Z4L5,P54802 7 +Photoreceptor cell development 0.5453260591225115 0.9713356433821264 0.3313811648790092 1.0 0.6292965063944507 4 Q8NBN7 1 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.5491506273864145 0.9709194266636294 0.3315884033957759 1.0 0.6295014117193025 6 O95881,O76024,O60313 3 +Mesenchymal cell proliferation 0.5425418298326791 0.9681029926663548 0.332992935435433 1.0 0.6310422134337028 3 P35222,P02545 2 +Regulation of mesenchymal cell proliferation 0.5425418298326791 0.9681029926663548 0.332992935435433 1.0 0.6310422134337028 3 P35222,P02545 2 +Positive regulation of peptidyl tyrosine phosphorylation 0.5574831948239596 0.9678944603168148 0.333097081258598 1.0 0.6310422134337028 14 Q13432,Q92769,Q06124 3 +Neuron development 0.3106719546425769 0.963702705117007 0.3351949977290005 1.0 0.6338796480479487 155 O00264,Q9NZJ7,Q9NQC3,Q9UQB8,Q8WWV3,O60678,P61160,Q7L7X3,P08670,P30536,Q8TEY7,Q9Y4W6,Q9BW83,Q13555,Q9BVA1,Q06124,Q8NBN7,Q9Y263,P35613,O75312,Q99829,Q8NHS3,P54802,Q02750,O14949,Q92769,O43175,P42892,Q86VR2,Q9UJX6,Q7L576,Q32P28,Q96PU5,Q86X55,O14976,Q96G23 36 +Positive regulation of calcium ion transport 0.5581435799323827 0.96186455114977 0.3361176473449516 1.0 0.6338885576675803 18 P42858,O14936,O76024,Q96GC9,P30536 5 +Selective autophagy 0.557645526912092 0.9617006282791496 0.3362000066783552 1.0 0.6338885576675803 24 P12235,O15269,P42858,P21796,Q86VR2,Q96HY6,Q9Y679 7 +Atp synthesis coupled proton transport 0.552037633484795 0.9538342265063594 0.3401675613830619 1.0 0.638129028670014 11 O75964,P24539,P06576,P36542,P56134 5 +Positive regulation of cytoplasmic translation 0.5529681855902451 0.9536248097074076 0.3402735927717286 1.0 0.638129028670014 12 O60506,Q9H074,P16989,P67809 4 +Development of secondary sexual characteristics 0.5370106761565826 0.9525939675015512 0.3407958348922046 1.0 0.6383899165935404 2 Q99623 1 +Development of secondary female sexual characteristics 0.5370106761565826 0.9525939675015512 0.3407958348922046 1.0 0.6383899165935404 2 Q99623 1 +Negative regulation of neuron projection development 0.5551879249395577 0.9507277821056818 0.3417425811882788 1.0 0.6383899165935404 16 Q92769,Q9NQC3,Q86X55,P08670,Q96G23 5 +Peptidyl tyrosine dephosphorylation 0.5489388065563283 0.949890817869864 0.3421677329120269 1.0 0.6386718843128345 9 Q3ZCQ8,Q9Y217,Q06124,P24666 4 +Regulation of nik nf kappab signaling 0.5526160197410915 0.9476688953860488 0.3432980405294534 1.0 0.640035211190099 13 Q53EL6,Q99829,O43657 3 +Adaptive thermogenesis 0.554715805916359 0.9462801148286856 0.3440057329935706 1.0 0.64094924002969 24 Q9UIQ6 1 +Fatty acid transport 0.5528062902298999 0.9448536025036072 0.3447336216608723 1.0 0.6417676147076815 14 O43772,P04083,P23786 3 +Nuclear transcribed mrna catabolic process exonucleolytic 0.5516170527402602 0.9390005952035704 0.3477304387469795 1.0 0.6435783282462328 14 Q96B26,Q9NQT4,Q6PGP7,Q969T7 4 +Regulation of release of cytochrome c from mitochondria 0.5476990651069746 0.9381686953544986 0.3481577232759911 1.0 0.6435783282462328 10 Q9H3K2,O00429,Q96A26,O14737,O60313 5 +Alpha linolenic acid metabolic process 0.5338078291814881 0.9377467988311904 0.3483745473611574 1.0 0.6435783282462328 2 O14734 1 +Response to hyperoxia 0.538023735840015 0.937189308525108 0.3486611883678234 1.0 0.6435783282462328 4 P49327 1 +Establishment of protein localization to endoplasmic reticulum 0.5535408072395683 0.9368133183576234 0.3488545932658686 1.0 0.6435783282462328 21 Q9Y5M8,Q9UGP8,Q15005,Q15629,O43765,P46379 6 +Negative regulation of phosphoprotein phosphatase activity 0.5392692440986524 0.9334856926449564 0.3505692541761618 1.0 0.6446474580441077 5 P62942 1 +T cell chemotaxis 0.5347098611605492 0.931640500819452 0.3515223449842837 1.0 0.6446474580441077 3 P55011,Q9H4A3 2 +Lymphocyte chemotaxis 0.5347098611605492 0.931640500819452 0.3515223449842837 1.0 0.6446474580441077 3 P55011,Q9H4A3 2 +Adenylate cyclase activating adrenergic receptor signaling pathway 0.5323843416370115 0.9311541068892972 0.351773853545275 1.0 0.6446474580441077 2 Q9Y4G8 1 +Adrenergic receptor signaling pathway 0.5323843416370115 0.9311541068892972 0.351773853545275 1.0 0.6446474580441077 2 Q9Y4G8 1 +Gamma aminobutyric acid signaling pathway 0.5323843416370065 0.931154106889274 0.351773853545287 1.0 0.6446474580441077 2 P55011 1 +Response to acetylcholine 0.5323843416370038 0.9311541068892616 0.3517738535452934 1.0 0.6446474580441077 2 P46109 1 +Histone h3 k36 methylation 0.5363147371349526 0.9292114553767332 0.3527795119156902 1.0 0.6459300106933629 4 Q96ST2,O96028 2 +Regulation of amino acid transport 0.540010966678835 0.9278355173828848 0.3534928972098463 1.0 0.6468623995434006 6 Q15041 1 +Regulation of ion transport 0.3962539784233471 0.9273023107658322 0.3537695949165755 1.0 0.6469437560919818 74 Q13555,P51809,P62942,P21796,P42858,Q9Y4C2,O14936,O76024,O43865,Q4KMQ2,Q96PU5,Q15041,Q96GC9,O75844,P20020,P30536 16 +Peptidyl lysine hydroxylation 0.5397420014464394 0.9265698868680396 0.3541498958313216 1.0 0.6469437560919818 6 Q96AY3 1 +Regulation of fertilization 0.5306049822063973 0.9229187597524012 0.3560495435426365 1.0 0.6500391695274237 2 Q9NVM9 1 +Monocarboxylic acid transport 0.5402438849386063 0.9216190650799166 0.3567273103670398 1.0 0.6506989132736195 7 P04083 1 +Memory 0.5385212061180753 0.920827141867491 0.3571406820195499 1.0 0.6510933549936387 6 O00264 1 +Regulation of response to endoplasmic reticulum stress 0.5502279422031947 0.9199422445080284 0.3576029414683352 1.0 0.6515611961141002 20 P18031,Q4ZIN3,O95881,O76024,Q96HY6,O43765,O60313,P46379 8 +In utero embryonic development 0.3519522840660611 0.9188481803674317 0.3581749875051059 1.0 0.6522007969709299 81 Q96AY3,Q02750,Q15363,P53992,Q15293,P67809,Q9NQC3,O43772,Q08J23,O43819,P23786,Q4VCS5,O95067,Q8TCT9 14 +Microtubule cytoskeleton organization 0.3073306412459987 0.918680449758864 0.3582627385601715 1.0 0.6522007969709299 149 P07437,O95684,Q9BVA1,Q8TEY7,Q9BV86,O94927,Q9BUF5,P42858,P68371,Q96DB5,O95067,Q14155 12 +Macromolecule depalmitoylation 0.5349974215505822 0.91347766626657 0.3609913744631474 1.0 0.6542885877878372 5 Q9NUJ1 1 +Regulation of peptidase activity 0.42244041183049 0.9129514592471452 0.3612680714327982 1.0 0.6542885877878372 69 Q9NR28,Q9BXK5,Q9NZJ7,P61289,P04080,Q96A26,Q15418,P16435,P49327,Q96K76,Q9P0J0,O95831,Q96HY6,Q15041,P51812,Q15392,P30086 17 +Cdp diacylglycerol metabolic process 0.5362208538772615 0.9100141983040534 0.3628150219859734 1.0 0.6553611558905963 6 O95674,Q99943,O96017 3 +Columnar cuboidal epithelial cell differentiation 0.5374893608151868 0.9086062711389298 0.3635579951217453 1.0 0.6558118460251922 7 P07437 1 +Amyloid fibril formation 0.5385199840558386 0.906568947424758 0.3646347890318515 1.0 0.6568194025283806 8 P61758,P62942 2 +Mitochondrial membrane organization 0.5276530948765864 0.90499515860793 0.3654679520434998 1.0 0.6571760636076834 40 Q9NS69,P12235,Q5XKP0,Q9NX63,P45880,Q9H3K2,Q9Y4W6,O95202,Q9P0J0,Q9NVH1,P52789,O60313,Q15070,Q13505,Q9UII2,O14737,Q6UXV4,Q3ZCQ8,O95140,Q53H12,Q9Y512 21 +Protein localization to microtubule end 0.5266903914590771 0.9048238348044066 0.3655587224581165 1.0 0.6571760636076834 2 Q15555 1 +Neuron death 0.4554579285905469 0.9040827320326718 0.3659515340477517 1.0 0.6575091781288921 62 Q9NR28,Q9UMX5,Q07820,Q4ZIN3,Q96A26,P09601,O95831,Q99720,P31751,Q15392 10 +Dna methylation or demethylation 0.5468498862456682 0.9024182583491056 0.3668347256295896 1.0 0.6585358799758384 21 Q03164,Q8N2A8,O75844 3 +Tricarboxylic acid metabolic process 0.5387298184417182 0.9011129332838969 0.3675282770755292 1.0 0.6590870179867147 9 P48735,P53396 2 +Mammary gland development 0.5456627871024711 0.9008760259793992 0.3676542393011215 1.0 0.6590870179867147 17 P00403,Q13505,Q9NQC3,P49327,P31751 5 +Ethanol metabolic process 0.5280792084080633 0.9008618722707948 0.3676617655961869 1.0 0.6590870179867147 3 P30837 1 +Vesicle cargo loading 0.542817324085498 0.8997965791050223 0.3682285152022879 1.0 0.6591706499539262 13 P49755,Q15363,P53992,Q96PC5,Q5JRA6,Q15437,P55735 7 +Positive regulation of cysteine type endopeptidase activity 0.5452085560035485 0.894983989716615 0.370795646558935 1.0 0.6616111856482496 23 Q9NR28,Q9BXK5,Q9NZJ7,Q96A26,P49327,O95831 6 +Phosphatidylglycerol metabolic process 0.5387022785172872 0.8949820047131487 0.3707967076864382 1.0 0.6616111856482496 10 Q92604,Q8NCC3,Q8NF37,Q9UJZ1,O95674 5 +Immune response regulating signaling pathway 0.5030094340396067 0.8946969395751418 0.3709491151346427 1.0 0.6616111856482496 49 Q96IZ0,Q07021,Q9NQC3,Q9UKG1,O43657,Q9NPR9,Q9H4A3,Q8ND56,O75179,Q9NUD5,P04439,Q07666,P17931,P05771,P51812,Q9NR50,P46379,Q14671,Q96J02 19 +Gamete generation 0.3164706578887551 0.8941528247396516 0.3712401290337268 1.0 0.6618667784892943 89 Q9BTX1,Q99417,Q8N2A8,Q9BPZ3,O95470,Q08J23,Q8NB78,Q9BW83,O95067,P46379 10 +Receptor diffusion trapping 0.5241992882562179 0.8933262925669163 0.371682461721075 1.0 0.6619875660276707 2 Q15334 1 +Neurotransmitter gated ion channel clustering 0.5241992882562179 0.8933262925669163 0.371682461721075 1.0 0.6619875660276707 2 Q15334 1 +Macromolecule catabolic process 0.2908529801090067 0.8906062807336338 0.3731404285567188 1.0 0.6634261539592354 386 Q969T7,P60900,P61289,Q08J23,O60506,Q8N511,Q9UIQ6,Q9NUJ1,O76024,Q9UHG3,Q12972,P08670,Q9BUN8,Q92804,O43765,Q9UBU6,Q8TEY7,Q14011,P28074,Q8NF37,O60502,Q16740,P16989,Q96K76,Q9P0J0,Q8IXB1,O95831,Q96HY6,P40818,Q96CS3,Q9Y5X3,P28072,P13489,Q99729,Q6PGP7,Q16850,P51116,P08236,Q13190,Q4ZIN3,Q9NQT4,Q9Y263,Q96A33,Q96JB5,Q14103,P51114,O75312,Q8NHS3,Q8TCT9,P54802,Q99436,O75844,P46379,P49721,Q96RU2,P67809,P27824,Q6PKG0,Q9UJX4,Q13217,O95376,P35637,Q9GZP9,Q9UJX6,Q15369,Q96PU5,Q9Y4Z0,Q96J02,Q9H000,Q9Y679,Q9H074,Q92945 72 +Response to hydrogen peroxide 0.543945371818136 0.8897232830874561 0.3736144888459245 1.0 0.6635636255091434 24 Q99720,O95831,P09601 3 +Schwann cell development 0.5298665421054469 0.8894966014440857 0.3737362488957387 1.0 0.6635938944388614 5 P31751 1 +Amine transport 0.5331124769214555 0.8879626613707952 0.3745608364799291 1.0 0.6646855280798966 7 Q15041 1 +Negative regulation of nervous system development 0.5435554465944916 0.886868247212387 0.3751498387433236 1.0 0.6652919780928204 19 Q9NQC3,Q96G23 2 +Meiosis i cell cycle process 0.5428330219948124 0.8867425270631875 0.3752175366425343 1.0 0.6652919780928204 17 O95067,Q9BTX1,P46379 3 +Intracellular transport 0.2965768501624672 0.8855949431590996 0.3758358375104782 1.0 0.6657950814435099 488 Q99595,Q9NS69,O60830,O60725,P18031,O14964,Q9UKG1,P61160,Q8N4H5,P23786,P43307,P45880,O75964,Q9Y282,P55786,O95831,Q9P2W9,Q9UBX3,P07437,Q9Y5M8,Q96L92,Q15629,O75844,P46379,O43772,Q08J23,O43865,Q9ULX6,P53992,Q96RQ1,Q7Z4L5,Q96CS3,P04792,O15260,O60313,Q15070,Q15388,P16615,Q06124,O14925,P42858,Q15005,Q8TCT9,O15027,Q5JRX3,Q3ZCQ8,P55735,Q9Y3B3,P31751,P50402,Q9NZJ7,Q9BUN8,P30536,O95070,Q9BW83,P24539,Q9Y5X3,Q13190,Q9UGP8,Q14168,Q12907,P40855,Q8N1F7,Q9UJS0,P51809,Q02750,Q15363,Q8TB36,Q9Y4C2,Q9GZP9,Q9Y679,Q9Y2T2,P12235,Q96ST2,O15118,Q15041,P56134,P22626,O43765,Q9Y678,Q96PC5,Q9P0J0,P52789,P06576,P49755,Q9Y3A6,Q07666,O75312,Q7Z4Q2,Q8TD16,Q9HCU5,Q9BVK6,O95376,Q8IUD2,Q53H12,Q12769,O14976,Q9Y512 98 +Regulation of transcription regulatory region dna binding 0.5340375423691818 0.8853225224769522 0.3759827060003986 1.0 0.6657950814435099 8 O75844 1 +Rna stabilization 0.5409817426772913 0.8850322124840561 0.3761392580364955 1.0 0.6657950814435099 28 Q14011,Q08J23,O60506,P35637,P16989,Q14103,Q92804,Q9H074,P67809 9 +Granulocyte activation 0.5318686911923561 0.882104323819159 0.3777203942291383 1.0 0.6674886051952174 7 P04083,P51809 2 +Regulation of neuron projection arborization 0.5236739053043843 0.8804665184156355 0.3786066353701374 1.0 0.6676457995409866 3 Q15334,Q9HCE1 2 +Regulation of defense response 0.3484827810213302 0.8800319340862228 0.3788420102096412 1.0 0.6677946644502076 81 P04083,Q07021,P18031,P60900,Q15233,Q9UKG1,P01889,Q8N2K0,O43657,Q8IZ81,Q96PK6,Q9NZ08,Q9NUD5,Q8IXJ6,Q06124,P04439,Q9Y3Z3,P51809,O75844,Q9H000,Q96J02,Q53EL6 22 +Thymocyte apoptotic process 0.5209964412811315 0.8785650953418523 0.3796371282150326 1.0 0.6688241538778598 2 P04637 1 +Connective tissue development 0.5415967450359432 0.87555947745884 0.3812695629430638 1.0 0.6706503906402336 22 Q06124,P43490,Q96HY6,O15173,O75844 5 +Regulation of epithelial cell apoptotic process 0.5345420951816423 0.8750714751059121 0.3815350166014972 1.0 0.670862208713565 10 O76024,Q53EL6,P09601 3 +Cellular response to fatty acid 0.5244067034403197 0.873792835343497 0.3822310829196698 1.0 0.6717133589744724 4 Q15120 1 +Protein folding 0.3158637502969355 0.8733602017920606 0.382466776305272 1.0 0.6717549782279681 95 P62942,P36404,P48643,O76024,O75718,Q99543,Q8IXB1,P61758,P04792,Q6ZRP7,Q15813,Q96A33,P40855,Q96KC8,P27824,Q13451,Q13217,Q9UBS4,Q32P28,P48723,O15212 21 +Negative regulation of intracellular signal transduction 0.3146879871415504 0.8713131094660348 0.383583214454779 1.0 0.6733426121883476 89 Q07021,P18031,O76024,P45880,Q9NUQ9,O43657,P16989,Q96K76,Q9P0J0,P04792,O60313,P30086,Q96S97,Q96JB5,Q99829,Q07820,O95881,Q9H000,Q96J02,Q53EL6 20 +Regulation of digestive system process 0.5192170818505236 0.8703753789001933 0.3840952973180105 1.0 0.6736816770285725 2 Q9H4A3 1 +Neuron cellular homeostasis 0.529212877953644 0.8696077922272057 0.3845147779535249 1.0 0.6740443009381708 7 Q7L7X3,Q13131,P20020 3 +Cellular response to hydrogen peroxide 0.539376856675546 0.8673722261160669 0.3857380944836808 1.0 0.6755203896243055 18 Q99720,O95831 2 +Positive regulation of calcium mediated signaling 0.518505338078282 0.8671017700696304 0.3858862508486622 1.0 0.6755203896243055 2 Q8IWX8 1 +Positive regulation of calcineurin mediated signaling 0.518505338078282 0.8671017700696304 0.3858862508486622 1.0 0.6755203896243055 2 Q8IWX8 1 +Regulation of translational initiation by eif2 alpha phosphorylation 0.5226528234374294 0.8656586413547781 0.3866773869770781 1.0 0.675873965734695 4 Q15363 1 +Positive regulation of fatty acid transport 0.5181494661921684 0.8654654633040265 0.3867833639803306 1.0 0.675873965734695 2 P14174 1 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.5298224874230003 0.8653867440802828 0.3868265542343558 1.0 0.675873965734695 8 P46379,Q9UGP8 2 +Negative regulation of g protein coupled receptor signaling pathway 0.5244032775204791 0.8640298564586696 0.3875714894444533 1.0 0.676781628164646 5 P31946,P16949,P04899,P50570 4 +Neuron projection arborization 0.524047025293901 0.8623718310787439 0.3884829364138618 1.0 0.6779995505520908 5 Q9NZI8,Q15334,Q13464,Q9HCE1 4 +Cotranslational protein targeting to membrane 0.5349196252962755 0.8613623832840497 0.3890384871302874 1.0 0.678035449104684 13 P43307,Q15629,Q9UGP8 3 +Proton transmembrane transport 0.5182696518067507 0.8609589292201296 0.3892606637044484 1.0 0.6780950279193116 41 P00403,P13073,P12235,O75964,Q7KZN9,P47985,Q96ES6,P56385,Q00325,P05023,P24539,Q9UDW1,P06576,P36542,P56134,Q13423 16 +Neutral lipid biosynthetic process 0.5227514911929639 0.8563451630297311 0.3918068870762625 1.0 0.679868631818805 5 Q92604,Q8NCC3 2 +Embryonic axis specification 0.5244611480046556 0.8549243825476172 0.3925930113016544 1.0 0.68018707037421 6 Q8N2A8 1 +Embryonic pattern specification 0.5244611480046556 0.8549243825476172 0.3925930113016544 1.0 0.68018707037421 6 Q8N2A8 1 +Neuron differentiation 0.3052198798118259 0.8548751646456142 0.392620260912907 1.0 0.68018707037421 183 O00264,Q9NZJ7,Q9NQC3,Q9UQB8,Q8WWV3,O60678,P61160,Q7L7X3,P08670,P30536,Q8TEY7,Q9Y4W6,Q9BW83,Q7Z4L5,O60443,Q13555,Q9BVA1,Q06124,Q8NBN7,Q9Y263,Q8WUJ1,Q96JB5,P35613,O75312,Q99829,Q8NHS3,P54802,Q02750,O14949,Q92769,O43175,P42892,Q86VR2,Q9UJX6,Q7L576,Q32P28,Q96PU5,Q86X55,O14976,Q96G23 40 +Attachment of mitotic spindle microtubules to kinetochore 0.524445133243397 0.8548495960916026 0.3926344174576077 1.0 0.68018707037421 6 Q96DB5 1 +Regulation of peptidyl tyrosine phosphorylation 0.5370978268977906 0.8528531589734047 0.3937407401943529 1.0 0.6815446792165021 23 Q13432,O95684 2 +Regulation of focal adhesion disassembly 0.5176219295122791 0.8525263323016293 0.3939220303322379 1.0 0.6816722846027832 3 Q6DN90,Q15555 2 +Hormone biosynthetic process 0.5276536529322047 0.8484518509121743 0.3961863765704216 1.0 0.6840962039037499 9 Q8NBQ5,P05023,P16435,Q53GQ0,P30536 5 +Cell recognition 0.5358722707809046 0.8480835480439205 0.3963914432540059 1.0 0.6842424440013001 19 Q9NQC3 1 +Sterol biosynthetic process 0.5361444472036513 0.8479119276139798 0.3964870213622808 1.0 0.6842424440013001 23 Q16850,P53396,Q15800,P16435,O76054,P48449,Q15392,Q14534 8 +Regulation of nucleobase containing compound transport 0.5287189983808016 0.8472749950133011 0.3968418607106798 1.0 0.6846683559280093 10 Q9ULX6,Q96ST2,Q08J23 3 +Camera type eye morphogenesis 0.522182473682298 0.8442904480551128 0.3985071224272507 1.0 0.6867400996878602 6 P54802,Q8NBN7 2 +Regulation of protein stability 0.3136757967757974 0.8432875199006682 0.3990676608916295 1.0 0.6867400996878602 96 Q96RU2,Q8TEY7,Q9NQC3,O15027,P42858,Q96K76,O76024,Q32P28,O75718,Q96HY6,P40818,P48449,P40855,Q9BUN8,Q96PU5,P46379 16 +Cell junction disassembly 0.5178062678062738 0.8432239198556214 0.399103223071906 1.0 0.6867400996878602 4 Q6DN90,Q15555,Q00535 3 +Neutrophil mediated immunity 0.5198179270792137 0.8427156067559952 0.3993875165928471 1.0 0.6867473058326484 5 Q8N5M9,P51809 2 +Hindbrain morphogenesis 0.5270821473005747 0.8394780886996503 0.4012010798678309 1.0 0.6884406290610465 10 Q02750,Q7Z4L5,Q06124 3 +Regulation of catabolic process 0.2956512358290191 0.8387355294941248 0.4016177359454538 1.0 0.6889690288809801 278 P12235,Q969T7,Q9NZJ7,P18031,P61289,Q08J23,P21796,O60506,P36404,O15118,P08670,Q92804,O43765,Q9Y487,P30536,O15269,Q8TEY7,Q14011,Q93050,Q8NF37,Q15042,P16989,Q9P0J0,O95831,Q96HY6,P40818,Q9Y5X3,P04792,Q99729,Q16850,P51116,P11802,O75874,Q13190,Q4ZIN3,Q9NQT4,P42858,Q14103,Q96JB5,P51114,Q8NHS3,Q86UE4,O75844,P46379,P67809,Q6PKG0,Q07820,O95376,P35637,Q9UJX6,P09601,Q96B26,Q96PU5,Q9H000,Q96J02,P31751,Q92889,Q9H074,Q92945 59 +Bone mineralization 0.5224881410746749 0.8380481673856905 0.4020036518321537 1.0 0.6892259926792119 7 Q4KMQ2,O75844 2 +Anterior posterior axis specification 0.5224611991842625 0.8379219813273108 0.402074522499291 1.0 0.6892259926792119 7 Q8N2A8 1 +Intrinsic apoptotic signaling pathway in response to dna damage 0.534180890978663 0.83737854469146 0.4023798218510717 1.0 0.6895297271688051 22 Q96RU2,Q07820,P09601,Q96K76,P46379 5 +Regulation of calcium ion transport 0.5295440124498837 0.8367176924243617 0.4027512718197572 1.0 0.6899796727552856 31 Q13555,P62942,P21796,P42858,O14936,O76024,Q96GC9,P30536 8 +Mitotic g2 dna damage checkpoint signaling 0.5236196556356749 0.8361343200889819 0.4030793428195656 1.0 0.6901685478107504 8 Q7L7X3,Q96JB5 2 +Calcium ion transmembrane transport 0.5205508782888145 0.8301716441393888 0.4064417448669108 1.0 0.6934898592411455 37 P16615,Q8IYU8,P62942,P21796,P42858,Q4KMQ2,P20020,Q96GC9,Q9BPX6 9 +Gland development 0.458379573838997 0.8287602906199215 0.407240062210243 1.0 0.6944780070576722 59 P00403,Q02750,P04083,Q13505,Q9NZJ7,Q9NQC3,Q15418,Q9UGP8,Q96JB5,P49327,P09601,P52789,O95067,O75844,P31751,P30536 16 +Regulation of insulin receptor signaling pathway 0.5266626891134025 0.8262755574354802 0.4086477956089696 1.0 0.6956817984697626 12 P11802,Q9HCD5,Q06124,P18031,P05771,Q9Y5X3,Q9BZF1 7 +Lung associated mesenchyme development 0.5085409252668932 0.8214198845835418 0.4114071410143953 1.0 0.6987636163517082 2 P35222 1 +Regulation of receptor signaling pathway via stat 0.5185242044071403 0.8195058944309254 0.412497840334975 1.0 0.7003508543605452 7 Q9NX40,Q6IA86 2 +Protein targeting to membrane 0.5281030101815154 0.8193921964921176 0.4125626857074191 1.0 0.7003508543605452 29 O60725,Q9Y4C2,Q9UGP8,P40855,Q15041,P43307,Q15629,P31751,P46379 9 +Collagen metabolic process 0.5203214604365143 0.8137746981353476 0.4157740323969205 1.0 0.7031811751595244 9 P08670,Q32P28 2 +Endoplasmic reticulum unfolded protein response 0.528889160990141 0.8129738615942026 0.4162330445268163 1.0 0.7037536828085472 19 Q15363,P18031,Q9GZP9,Q9Y4P3,Q96JB5,O76024,Q96HY6,Q9BUN8 8 +Ubiquitin dependent erad pathway 0.5257494682407189 0.8109093842613173 0.4174177107587948 1.0 0.7053802754875955 30 Q9UBU6,Q9GZP9,Q96A33,O76024,Q8IXB1,Q96CS3,Q9BUN8,Q9Y679,O43765,P46379 10 +Negative regulation of organ growth 0.5056939501779277 0.8084234928882403 0.4188468323511642 1.0 0.705725173254275 2 P11413 1 +Regulation of cell growth involved in cardiac muscle cell development 0.5056939501779277 0.8084234928882403 0.4188468323511642 1.0 0.705725173254275 2 P11413 1 +Negative regulation of cell growth involved in cardiac muscle cell development 0.5056939501779277 0.8084234928882403 0.4188468323511642 1.0 0.705725173254275 2 P11413 1 +Negative regulation of cardiac muscle tissue growth 0.5056939501779277 0.8084234928882403 0.4188468323511642 1.0 0.705725173254275 2 P11413 1 +Glucosylceramide metabolic process 0.5049822064056875 0.805178585110797 0.4207166323371889 1.0 0.7077465620177446 2 Q13131 1 +Positive regulation of nervous system process 0.5049822064056828 0.8051785851107759 0.4207166323372011 1.0 0.7077465620177446 2 O75746 1 +Histone h2a k63 linked ubiquitination 0.5071692712627502 0.8045169730461426 0.4210984709524887 1.0 0.7082009051024207 3 Q96FW1 1 +Reticulophagy 0.5092857403488592 0.8039506573551003 0.4214254723055264 1.0 0.7083748588859737 4 Q96HY6 1 +Pancreas development 0.5134144262372002 0.8035163364966639 0.4216763582530767 1.0 0.7085157491712012 6 P04083 1 +Positive regulation of deoxyribonuclease activity 0.5039145907473197 0.8003144536710607 0.4235286309394097 1.0 0.710098606130978 2 P23396 1 +Regulation of heterotypic cell cell adhesion 0.5083973751354456 0.7998694561137973 0.4237864360383818 1.0 0.7101173473712832 4 Q96S97 1 +Physiological cardiac muscle hypertrophy 0.5058739765040895 0.7985920526317207 0.4245269973963492 1.0 0.7105725257529492 3 P11413,Q96HC4 2 +Positive regulation of smooth muscle cell migration 0.503202846975078 0.7970738846822681 0.4254081223786314 1.0 0.7110886574963718 2 Q96N67 1 +Positive regulation of signaling 0.3017339325202741 0.7970169343833675 0.4254411963593825 1.0 0.7110886574963718 206 Q9Y4R8,Q9UMX5,Q07021,P18031,Q9NQC3,Q9UQB8,Q9NX40,P62942,P33176,Q7L7X3,P49327,P57088,O95071,Q15750,O43657,P30154,O00429,Q15042,Q96K76,Q7Z4L5,O75179,P40818,Q9Y5X3,Q9NUD5,Q9BZF1,O60443,Q06124,Q9BPZ3,P42858,Q96AG4,Q96JB5,Q14168,Q8TB61,Q99829,Q86UE4,Q8N1F7,P51809,Q02750,Q07820,P42892,Q969T9,P09601,Q7L576,P55735,P16435,Q53EL6,Q99943 47 +Regulation of cilium assembly 0.5223428597700601 0.7959352160525652 0.4260696911020551 1.0 0.7110886574963718 14 P42858,Q9Y277 2 +Motor behavior 0.5051619793520777 0.7953377131645476 0.4264170814491517 1.0 0.7112937733991246 3 Q13131,Q14203 2 +Adiponectin activated signaling pathway 0.5071225071225225 0.7940173861287632 0.4271853099038054 1.0 0.7117881967015887 4 Q06481,P33121,Q9UKG1 3 +Regulation of anion transmembrane transport 0.5112862464888022 0.7936570815935261 0.4273950920248923 1.0 0.7117881967015887 6 Q9Y4C2 1 +Cartilage development 0.5190515188871714 0.7897764579648873 0.4296583300926075 1.0 0.7138817089137005 12 Q06124,O75844,Q96HY6 3 +Male meiosis i 0.5014234875444846 0.7889802713575814 0.4301235373986853 1.0 0.7144673280459946 2 Q15645 1 +Ovulation cycle 0.5133915423639805 0.7881523913956255 0.4306075729598304 1.0 0.7150839071924647 8 O95470 1 +Fc receptor mediated stimulatory signaling pathway 0.5057316686198747 0.787639490202204 0.430907608776863 1.0 0.7152073118960139 4 Q06481,Q9UKG1 2 +Regulation of fc receptor mediated stimulatory signaling pathway 0.5057316686198747 0.787639490202204 0.430907608776863 1.0 0.7152073118960139 4 Q06481,Q9UKG1 2 +Epithelial cell apoptotic process 0.5170031731651704 0.7855974794323607 0.4321033416192958 1.0 0.7162461406086116 11 O76024,Q53EL6,P09601 3 +Regulation of anoikis 0.5071265682555126 0.7840546982212665 0.4330080156232947 1.0 0.7171907462114006 5 O96017,Q07820 2 +Positive regulation of protein metabolic process 0.2869174801756779 0.780969020575475 0.4348207155028112 1.0 0.7196288519564676 284 Q9Y4R8,Q03164,Q07021,Q9NZJ7,P61289,P62942,O60506,Q567V2,Q7L7X3,P49327,O76024,Q86XL3,P08670,Q9BUN8,O43765,Q9ULX6,O43823,Q9BXK5,Q9Y2R0,Q14011,Q8NF37,Q15042,P16989,Q13432,Q9P0J0,O95831,Q96HY6,Q9BZF1,Q9NR28,P51116,Q06124,P15260,Q13190,Q4ZIN3,Q96A26,Q14103,Q96JB5,Q07666,P51114,P35080,Q9H7B4,Q6PKG0,P46379,P67809,Q02750,Q92769,Q13217,O95376,Q969T9,Q9UJX6,Q71RC2,Q96PU5,Q9H000,Q96J02,P31751,Q9H074 56 +Positive regulation of lipid biosynthetic process 0.5144727550355037 0.7796941927075055 0.4355708978868422 1.0 0.7206821879657753 10 Q8WTV0,Q13131,Q92604,P04083,P16435 5 +Nerve growth factor signaling pathway 0.4992882562277584 0.7792830597162661 0.435812991413965 1.0 0.7208913696773392 2 Q9Y4G8 1 +Male meiotic nuclear division 0.5016019935920264 0.7790931537233876 0.4359248427652775 1.0 0.7208913696773392 3 Q15645,Q8NI77 2 +Anoikis 0.5076214188737177 0.7767163746902696 0.4373261238335386 1.0 0.7223047584842213 6 Q9Y3E5,O96017,Q07820 3 +Regulation of water loss via skin 0.5055219095119304 0.7766768756556102 0.4373494332182353 1.0 0.7223047584842213 5 P16949,Q9Y3B8,Q15149,Q9NWH9 4 +Body morphogenesis 0.5075201297488481 0.7762488601407531 0.4376020619117859 1.0 0.722533680650075 6 O95470,Q06124 2 +Secondary alcohol metabolic process 0.5091572111471923 0.7733118501262474 0.4393378443179738 1.0 0.7238253067299197 38 Q16850,P53396,O75874,Q15800,P16435,Q9BQE5,P48735,O76054,P48449,P37268,Q15392,Q14534 12 +Regulation of low density lipoprotein particle clearance 0.5040541708648955 0.7699369961839264 0.4413372667946151 1.0 0.7262504942343537 5 Q92945 1 +Neuropeptide signaling pathway 0.4994660021359851 0.7693689417749189 0.4416743207424662 1.0 0.7266070016991196 3 Q9Y4G8,Q9Y3E5 2 +Positive regulation of interferon gamma production 0.5031449638943921 0.7657660297128841 0.4438155303941919 1.0 0.728616325416579 5 Q9NUQ9,Q01650 2 +Positive regulation of reproductive process 0.5050227194932838 0.7647339701803467 0.4444299735861048 1.0 0.7294360897734126 6 Q92769,Q07021 2 +Endothelial cell morphogenesis 0.4953736654804174 0.7615496369349968 0.4463288430493519 1.0 0.7317945351626761 2 Q9NWH9 1 +Negative regulation of cellular amide metabolic process 0.3247790317643587 0.7573822321244511 0.4488208978286108 1.0 0.7345588887001243 83 Q969T7,Q9NQC3,O60506,O95197,P31483,Q14011,Q9BWF3,P00374,P51116,Q9BPZ3,Q9NQT4,Q14103,P51114,Q6PKG0,P67809,Q96B26,Q9Y6M1,Q9H074,Q92945 19 +Mitotic dna replication 0.5082731026051149 0.7571797555764008 0.4489421770452235 1.0 0.7345588887001243 9 O75844 1 +Positive regulation of small molecule metabolic process 0.5128314421466352 0.7548320180568135 0.45034977997138 1.0 0.7359277398123057 13 P31751,P04083,P16435 3 +Secondary metabolite biosynthetic process 0.4962620149519278 0.7548159195227834 0.4503594405857853 1.0 0.7359277398123057 3 Q9Y4G8,Q9UKG1 2 +Regulation of response to wounding 0.5161323812814615 0.7544851662656116 0.4505579492157809 1.0 0.735976941248146 17 O14936,Q96G23,Q4KMQ2,P04083 4 +Tetrapyrrole metabolic process 0.5175292611512682 0.7543787474699784 0.4506218292635011 1.0 0.735976941248146 20 Q7KZN9,Q9H3L0,O00264,P09601,P30536,P30519 6 +Neuron apoptotic process 0.4984854179976 0.7535699553658725 0.4511074907636474 1.0 0.7363905638766702 42 Q9NR28,O43813,Q07820,Q01105,Q96A26,P09601,P49327,O76024,O95831,Q99720,P31751 11 +Signal transduction in absence of ligand 0.5099297158227662 0.7520810244161097 0.4520023345442836 1.0 0.7366119643774076 11 P30154,Q07820 2 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.4956116520546164 0.7518669086608514 0.4521311000550878 1.0 0.7366119643774076 3 P42892 1 +Regulation of dendrite development 0.514806931080116 0.7479837787938948 0.4544699418725202 1.0 0.7392578693988294 17 Q9UQB8,Q8WWV3,Q9UJX6,Q7L576,Q96PU5,Q86X55 6 +Vasculogenesis 0.5047164510908857 0.7477452328724388 0.454613842046274 1.0 0.7392578693988294 8 O95470,Q4VCS5,Q92990 3 +Cellular response to biotic stimulus 0.5122397325103734 0.7467340587043417 0.4552241066023896 1.0 0.7395098610714189 32 Q8WTV0,Q9NUQ9,O43823,P11802,Q86UE4,Q9UM00,Q9Y263,Q96A33,O76024,O75844,P08670,Q53EL6,P30536 13 +Lipid translocation 0.5010943845491427 0.7466709744587315 0.4552621945306416 1.0 0.7395098610714189 6 Q96GC9 1 +Regulation of membrane lipid distribution 0.5010943845491427 0.7466709744587315 0.4552621945306416 1.0 0.7395098610714189 6 Q96GC9 1 +Negative regulation of leukocyte cell cell adhesion 0.5121053376201586 0.7465217588017385 0.4553522925517874 1.0 0.7395098610714189 14 Q96IZ0,P04083,Q5JRA6,Q92990,P17931,Q96J02 6 +Nik nf kappab signaling 0.5117883878620723 0.7449984667162914 0.4562726468006293 1.0 0.7404352785596895 14 Q53EL6,Q99829,O43657 3 +Regulation of myeloid leukocyte mediated immunity 0.502059123317627 0.7430594211321999 0.4574457058721735 1.0 0.7416689384214922 7 P09601 1 +Regulation of systemic arterial blood pressure 0.5001409612889804 0.7422965180559732 0.4579077010006434 1.0 0.7419910728955625 6 P42785,P09493,P42892 3 +Trna methylation 0.5065142308757564 0.7422532779503941 0.4579338939710502 1.0 0.7419910728955625 10 O75648 1 +Positive regulation of t cell proliferation 0.5027876348305858 0.7388017875271228 0.4600273662278336 1.0 0.7446215631636734 8 P30825 1 +Negative regulation of response to stimulus 0.2982900178965433 0.7359783439620445 0.4617438771614843 1.0 0.7463668024037421 208 P50402,P04083,Q07021,Q9UMX5,P18031,O14964,Q15233,Q9UKG1,P61289,P62942,O76024,P45880,P01889,O95071,O43765,Q9NUQ9,O43657,P16989,Q9NPR9,Q96K76,Q9P0J0,Q96HY6,Q9Y5X3,P04792,O60313,Q8N5M9,P30086,P04439,Q9Y3Z3,Q96S97,P42858,P80303,O14936,Q96JB5,Q99829,Q92896,P67809,Q07820,O95881,Q9UJX6,P09601,Q96FW1,Q9H000,Q96J02,Q96G23,Q92889,Q53EL6 47 +Negative regulation of glucose import 0.4896797153024926 0.7358659998155744 0.4618122506272528 1.0 0.7463668024037421 2 Q06481 1 +Negative regulation of calcium ion dependent exocytosis 0.4896797153024826 0.73586599981553 0.4618122506272799 1.0 0.7463668024037421 2 P04899 1 +Vesicle targeting to from or within golgi 0.5087272218972037 0.7352318736729652 0.4621982904061317 1.0 0.7466098818005752 13 P49755,Q9BVK6,Q15363,Q9HCU5,Q8N6H7,O15027,Q9NR31 7 +Nerve development 0.4982842370062414 0.7337886291245815 0.4630775717941096 1.0 0.7472682893963005 6 Q9H061,Q9Y4W6 2 +Regulation of lipase activity 0.5057443224486274 0.7323432185305839 0.4639591066045154 1.0 0.7483097120266772 11 P04083,P16435 2 +Regulation of phosphatidylcholine metabolic process 0.4934517363088201 0.731649729786538 0.4643823867439198 1.0 0.748707998076089 4 Q8NF37 1 +Regulation of cell aging 0.5068180141671657 0.7315515244917126 0.4644423450271588 1.0 0.748707998076089 12 O75844 1 +Negative regulation of response to endoplasmic reticulum stress 0.5053832398266628 0.7306438922466972 0.4649966948750588 1.0 0.7494110008706122 11 O95881,O76024,O60313,Q96HY6,O43765 5 +Positive regulation of phospholipase activity 0.4974551421760161 0.729994358669355 0.4653936328994434 1.0 0.74947889496411 6 P18085,Q9Y263 2 +Positive regulation of lipase activity 0.4974551421760161 0.729994358669355 0.4653936328994434 1.0 0.74947889496411 6 P18085,Q9Y263 2 +Regulation of mitochondrion organization 0.5043021528314929 0.7281015471138355 0.4665514268617161 1.0 0.7507710492693487 36 Q8N2A8,P21796,Q96A26,P42858,Q9Y6C9,O60313,P30536 7 +Response to iron ion 0.4946371997362007 0.7268994148775703 0.4672875756576335 1.0 0.7514968562494087 5 P09601 1 +Ire1 mediated unfolded protein response 0.4967305081149299 0.7266806194415804 0.4674216284899071 1.0 0.7514968562494087 6 P18031,Q96HY6 2 +Regulation of fatty acid biosynthetic process 0.4983975954530363 0.7262035478598378 0.4677139973248647 1.0 0.7514968562494087 7 P04083 1 +Negative regulation of glucose transmembrane transport 0.4898540405838268 0.7258376989891955 0.467938273002364 1.0 0.751666625099108 3 P05771,Q06481 2 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.5055080864728628 0.7253533733268582 0.4682352699134011 1.0 0.7519530931173904 12 O60506,Q9H074,P67809 3 +Regulation of translational fidelity 0.5056910206120141 0.720778543507671 0.471045778731948 1.0 0.7557005316011024 13 Q99543 1 +Chromatin remodeling at centromere 0.4861209964412689 0.7198850259748557 0.4715957882855868 1.0 0.7563914225172776 2 Q9NRZ9 1 +Regulation of membrane repolarization 0.4949181607268286 0.7184030815423118 0.4725087873249225 1.0 0.7573194196139614 6 O75844 1 +Regulation of gliogenesis 0.5022996763830124 0.7161556133751767 0.4738952671536296 1.0 0.7588595361405756 11 Q92769,Q96G23,P30536 3 +Antigen processing and presentation 0.5092012033945246 0.7149072781078266 0.4746663394565757 1.0 0.759777871466613 19 P04439,Q9UIQ6,Q9NZ08,P01889,P10321 5 +Positive regulation of blood pressure 0.487226486868485 0.7140079067263796 0.4752222902889729 1.0 0.7602836792631208 3 P09493 1 +Detection of stimulus 0.502529941820815 0.711290467198779 0.4769042576405864 1.0 0.7612449069693693 12 Q8WTV0,P04439,Q13432,P01889,P30536 5 +Regulation of macroautophagy 0.4824820349064363 0.7093725594843392 0.4780933116034807 1.0 0.7623747648795312 46 P12235,O15269,Q93050,Q15042,P21796,P42858,P09601,O15118,Q9Y5X3,Q9Y487 10 +Regulation of ph 0.5079399286656378 0.7086799077853844 0.4785231360284832 1.0 0.7626763362707489 19 Q8N511,Q9Y487 2 +Regulation of cellular ph 0.5079399286656378 0.7086799077853844 0.4785231360284832 1.0 0.7626763362707489 19 Q8N511,Q9Y487 2 +Negative regulation of muscle hypertrophy 0.4882478632478698 0.7081162586169641 0.4788730637890364 1.0 0.7630421436336745 4 P11413,O94826,P02545 3 +Homeostatic process 0.2852939053735273 0.7032551413196475 0.4818967609483258 1.0 0.765917734013336 268 O75880,P04083,Q9P035,Q8IYU8,Q9NQC3,P42785,Q9NX40,O43819,P62995,Q8N511,Q9UIQ6,P62942,Q9HD20,Q7L7X3,Q8NEW0,O76024,P23786,O15118,P49327,O95067,P20020,Q9Y487,P30519,P30536,Q9Y4W6,Q93050,Q8NF37,P52789,Q9Y5X3,P06576,P04792,O15260,Q9BPX6,P53985,P16615,Q06124,Q8NE01,P42858,Q5BJF2,Q9Y263,Q96A33,Q96JB5,O15254,Q4KMQ2,Q15067,Q07820,P09601,Q15120,Q96PU5,Q9Y6C9 50 +Regulation of cell projection organization 0.3034082108056494 0.702539230822417 0.4823429450115681 1.0 0.7660995814807431 101 Q9NQC3,Q9UQB8,Q8WWV3,P08670,Q14155,Q13555,P51116,P42858,P51114,P35080,Q02750,Q66K14,Q92769,Q86VR2,Q9UJX6,Q7L576,Q32P28,Q96PU5,Q86X55,O14976,Q96G23,Q9Y277 22 +Jnk cascade 0.5038754313437912 0.7025063015224222 0.4823634732693964 1.0 0.7660995814807431 15 Q9P035,Q53EL6,Q96J02 3 +Regulation of neuron differentiation 0.5034363140034757 0.700400536052898 0.4836772015998494 1.0 0.7672130449461517 15 Q99829,Q8WUJ1 2 +Fat cell proliferation 0.481138790035591 0.6976108142001437 0.4854206167352601 1.0 0.769027612062836 2 Q13501 1 +Rig i signaling pathway 0.4982455665661556 0.6971740630353619 0.4856938686549674 1.0 0.7691106929460841 11 Q14671,Q07021,O75179,Q8ND56,Q9NUD5 5 +Muscle adaptation 0.498867744972495 0.6940544930928775 0.4876480355843136 1.0 0.7713993014223153 12 P16615,P09601 2 +Positive regulation of calcium ion transmembrane transporter activity 0.4958341637721811 0.6924338191966631 0.4886649336773683 1.0 0.7726221768247213 10 Q96GC9 1 +Cell projection organization 0.2954867879683628 0.6919378134109807 0.4889763826868059 1.0 0.7729217603108727 211 O00264,Q9NQC3,Q9UQB8,A6NIH7,Q8WWV3,O60678,P61160,Q7L7X3,P08670,P30536,O95684,Q8TEY7,Q9Y4W6,Q9BW83,Q7Z4L5,Q14155,Q13555,Q9BVA1,P51116,Q06124,P42858,Q9Y263,P35613,P51114,Q4KMQ2,O75312,Q99829,P35080,Q02750,Q66K14,Q92769,O43175,P42892,Q86VR2,Q9UJX6,Q7L576,Q32P28,Q96PU5,Q86X55,O14976,Q96G23,Q9Y277 42 +Negative regulation of smooth muscle cell proliferation 0.4905052281132394 0.6900787409735677 0.4901446713842252 1.0 0.7739724822333395 7 O95140,P09493,Q53EL6,P09601 4 +Negative regulation of inflammatory response to antigenic stimulus 0.4855271016863454 0.6856408500062958 0.4929396149691198 1.0 0.7767399601030569 5 Q9H000 1 +Response to oxygen levels 0.4496418123686743 0.6836617925956162 0.4941887552269279 1.0 0.7780556874218739 56 P55786,Q96A26,Q8N511,O95831,Q9Y487,P30519 6 +Lactation 0.4921549216068701 0.6823954751202186 0.4949889161778615 1.0 0.77884643797166 9 P00403,Q13505 2 +Response to virus 0.3307354817356941 0.6822834736021972 0.4950597210272758 1.0 0.77884643797166 81 Q9NVI7,P15260,O43657,Q9Y3Z3,Q9NQT4,Q13217,Q9NUD5,Q9Y679,P48643,O75179,Q96J02,P04792,O60443,O75844 14 +Vesicle targeting rough er to cis golgi 0.4934679191126108 0.6814696658941658 0.4955743544834012 1.0 0.7794163748874253 10 P49755,Q15363,O15027 3 +Protein polyubiquitination 0.479899602509041 0.678832314674206 0.4972441161381469 1.0 0.7803415445687802 45 Q9UJX4,P55786,P52888,O95376,Q9UJX6,Q9Y263,Q9UIQ6,Q96PU5,Q9H000,Q96J02,O95071,Q96FW1 12 +Negative regulation of cell development 0.50296647050531 0.6787551085587898 0.4972930420360073 1.0 0.7803415445687802 22 Q9NQC3,Q96G23 2 +Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.4897303169354465 0.6787008888843301 0.4973274028449213 1.0 0.7803415445687802 8 O95881,O76024,O60313 3 +Vascular associated smooth muscle cell proliferation 0.4928566979199548 0.678642188793672 0.4973646044679349 1.0 0.7803415445687802 10 Q14344,P09601,O95140,P09493,Q53EL6 5 +Acetyl coa biosynthetic process 0.4874593455420091 0.676218995500349 0.498901613935669 1.0 0.7823656341277739 7 P53396 1 +Negative regulation of intrinsic apoptotic signaling pathway 0.5007484755924669 0.6758402059043337 0.4991421046620101 1.0 0.7824645219315185 30 Q07820,P18031,O95881,P16989,Q96K76,O76024,Q9P0J0,P45880,P04792,O60313 10 +Response to inorganic substance 0.2997179545338921 0.6731791716014366 0.5008333103667622 1.0 0.7844177509445002 91 P04083,O15118,O43865,P36551,P30536,P31939,O95831,O60888,Q14103,Q14168,P35613,Q99829,Q99720,Q9UJS0,Q92769,P09960,P09601,Q96PU5,P35611 19 +Regulation of transport 0.2819949646785867 0.6729911558977828 0.5009529174802576 1.0 0.7844177509445002 285 Q03164,P50402,P04083,Q96ST2,Q14C86,P18031,O14964,Q9UKG1,P21796,Q08J23,O60343,P62942,P33176,O43865,O76024,Q86U90,Q15041,P05023,P20020,P30536,Q9ULX6,Q9Y282,Q9BZF3,P61978,P55786,Q15042,Q13432,Q7Z4L5,P52789,Q9P2W9,Q9Y5X3,O15260,Q9BZF1,Q8N5M9,P53985,Q13555,P49755,Q16850,P16615,Q06124,P42858,Q9Y263,O14936,Q07666,P35080,Q4KMQ2,Q12907,O75312,Q96KC8,Q8NCW5,O75844,P51809,Q02750,Q9HCU5,Q9Y4C2,Q9GZP9,O95376,P09601,Q7L576,Q32P28,Q96PU5,Q96GC9,P31751 63 +Mitotic g2 m transition checkpoint 0.4943278639314279 0.6727803772305835 0.5010870233594558 1.0 0.784433909839148 12 Q7L7X3,Q96JB5,Q9Y619 3 +Porphyrin containing compound metabolic process 0.4998025320412804 0.6715783943534511 0.5018521366542976 1.0 0.7850498617571671 18 Q7KZN9,O00264,P09601,P30536,P30519 5 +Regulation of t cell differentiation 0.4906788321890863 0.6685834474399646 0.5037612343647146 1.0 0.7872589253191608 10 O96005 1 +Low density lipoprotein particle clearance 0.487165491799168 0.6669946157084056 0.5047755726658831 1.0 0.7881061210177505 8 P09601,Q92945 2 +Regulation of the force of heart contraction 0.4790749658190218 0.6669551030916456 0.5048008119316789 1.0 0.7881061210177505 4 P16615 1 +Protein localization to organelle 0.2820586921828511 0.6648834379704778 0.5061250496681642 1.0 0.7897843978692825 290 Q99595,Q9NS69,O60830,Q9NQC3,O14964,Q9UKG1,P36404,P48643,Q8N4H5,Q9UFC0,Q96DY7,O95071,O43765,P30536,P55786,P31483,Q5JRA6,O00429,Q15042,O15258,Q9P0J0,Q7Z4L5,O95831,Q96HY6,P52789,Q9BZF1,Q15070,O43292,P49755,Q15388,O14925,Q9Y5M8,Q9Y6X3,Q96A33,Q96JB5,Q9UGP8,Q15005,O75312,P40855,Q15629,Q7Z4Q2,Q8N1F7,Q8TD16,P46379,P67809,O15027,Q8TB36,O95376,O14976,Q5JRX3,Q3ZCQ8,P55735,Q8NFQ8,Q53H12,Q9Y6C9,Q9Y679,Q9Y512,Q9Y2T2,Q9NPA0 59 +Peripheral nervous system development 0.48819109611612 0.6641973111615245 0.5065640341857665 1.0 0.790274811579321 9 P21266,P31751,P51648 3 +Ceramide biosynthetic process 0.4856513453774399 0.6601004490542633 0.5091893705482242 1.0 0.7926143554812324 8 O15269 1 +Leukocyte homeostasis 0.4853792951728333 0.6588630951448677 0.5099836862105942 1.0 0.7932662296309612 8 O95067,P04083 2 +Regulation of lipoprotein particle clearance 0.481492835811714 0.6575831462106367 0.510806027276772 1.0 0.7941329536291801 6 Q92945 1 +Sertoli cell development 0.4745461018155955 0.657398193190591 0.5109249130928015 1.0 0.7941329536291801 3 P51153,P51659 2 +Negative regulation of nitric oxide metabolic process 0.4745049355969454 0.6572158077082672 0.5110421626794692 1.0 0.7941329536291801 3 Q92945 1 +Formation of translation preinitiation complex 0.482486409775573 0.6536964716598919 0.5133073768855234 1.0 0.7968713491728472 7 P55010 1 +Response to interleukin 1 0.4872274649301349 0.652695502098565 0.5139526027902552 1.0 0.7976776007547997 10 P04083 1 +Srp dependent cotranslational protein targeting to membrane 0.4853940959780924 0.651407459200162 0.5147834968099261 1.0 0.7987715522244128 9 Q15629 1 +Sertoli cell differentiation 0.474715099715104 0.6475488432168668 0.5172767937820819 1.0 0.8012669377162193 4 Q14151,P51153,P51659 3 +Astrocyte differentiation 0.487424477912652 0.6469178994599478 0.5176850805722482 1.0 0.8015075386235858 11 P08670,Q7Z4L5,Q06124,P15260 4 +Lipoprotein biosynthetic process 0.4841533149078496 0.6457478732863073 0.5184426513070606 1.0 0.8022884203499006 9 Q92643,Q15042,O43292,Q96S52 4 +Negative regulation of t cell proliferation 0.4784101106290936 0.6437531528406392 0.5197355165210173 1.0 0.8036176582642992 6 Q96J02,Q92990 2 +Negative regulation of leukocyte proliferation 0.4784101106290936 0.6437531528406392 0.5197355165210173 1.0 0.8036176582642992 6 Q96J02,Q92990 2 +Purine ribonucleoside salvage 0.4782396557572332 0.6429900399166636 0.5202305627489261 1.0 0.8036176582642992 6 Q13126 1 +Purine nucleoside biosynthetic process 0.4782396557572332 0.6429900399166636 0.5202305627489261 1.0 0.8036176582642992 6 Q13126 1 +Nucleoside salvage 0.4782396557572332 0.6429900399166636 0.5202305627489261 1.0 0.8036176582642992 6 Q13126 1 +Regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4841601885266103 0.6386321617169564 0.5230622536789453 1.0 0.8067884846543042 10 Q07820 1 +Negative regulation of guanyl nucleotide exchange factor activity 0.4702741189035279 0.6385234258215289 0.5231330098539586 1.0 0.8067884846543042 3 P16949,Q9NWH9 2 +Female meiosis chromosome segregation 0.4672597864768689 0.6362430136936467 0.524618041405361 1.0 0.8085227611025845 2 Q15003 1 +Regulation of anaphase promoting complex dependent catabolic process 0.4672597864768689 0.6362430136936463 0.5246180414053612 1.0 0.8085227611025845 2 P24941 1 +Response to topologically incorrect protein 0.4631679562558937 0.6336877816106542 0.5262846003879695 1.0 0.8096627681147146 49 Q15363,Q13217,Q9GZP9,Q9Y4P3,Q96JB5,O76024,P48723,Q96HY6,Q15629,Q96CS3,Q9BUN8,P04792,P46379 13 +Schwann cell differentiation 0.4761077954541137 0.6334603602272104 0.5264330588505397 1.0 0.8096627681147146 6 P31751 1 +Response to hepatocyte growth factor 0.4710700437309533 0.6314087343715457 0.527773306477259 1.0 0.8113778367652571 4 Q8IXJ6,Q9UKG1 2 +Negative regulation of cell population proliferation 0.3075033609136072 0.6290645026938518 0.5293068285790228 1.0 0.8123948719510348 84 P50402,Q15392,P09601,O14936,Q32P28,Q96J02,Q96DY7,Q53EL6,Q96G23,O60443 10 +Regulation of guanyl nucleotide exchange factor activity 0.4704415954415951 0.6286340843461875 0.5295886406864012 1.0 0.8123948719510348 4 P16949,Q9NWH9,Q9Y2S7 3 +Sterol metabolic process 0.4885391963607363 0.6270145729807787 0.530649682602182 1.0 0.813038452284823 34 Q16850,P53396,Q15800,P16435,Q9BQE5,O76054,P48449,P37268,Q15392,Q14534 10 +Endoplasmic reticulum to golgi vesicle mediated transport 0.4380321970364023 0.6252272620599582 0.5318219116158072 1.0 0.814440660683753 57 Q9Y678,P49755,Q9Y282,Q9HCU5,P53992,Q96PC5,Q15363,Q13190,O95070,Q9Y3A6,Q96RQ1,O15027,P55735,Q12907,Q9P2W9,Q9Y3B3,P51809 17 +Dna modification 0.4923150189090702 0.6248534523631841 0.5320672449308474 1.0 0.8144903122345809 27 Q03164,Q8N2A8,Q8NB78,O75844 4 +Regulation of translational initiation in response to stress 0.4741049609930133 0.6245323759946804 0.5322780148333917 1.0 0.8145486066165667 6 Q15363 1 +Cellular response to topologically incorrect protein 0.4901989020910418 0.6229124323905881 0.5333420677232037 1.0 0.8148862643802306 31 Q15363,P18031,Q9GZP9,Q9Y4P3,Q96JB5,O76024,P48723,Q96HY6,Q9BUN8,Q9Y679,P46379 11 +Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.4640569395017668 0.6222392206541133 0.5337845799972101 1.0 0.8148862643802306 2 P04637 1 +Cell surface receptor signaling pathway involved in heart development 0.4640569395017659 0.6222392206541093 0.5337845799972127 1.0 0.8148862643802306 2 P35222 1 +Wnt signaling pathway involved in heart development 0.4640569395017659 0.6222392206541093 0.5337845799972127 1.0 0.8148862643802306 2 P35222 1 +Canonical wnt signaling pathway involved in heart development 0.4640569395017659 0.6222392206541093 0.5337845799972127 1.0 0.8148862643802306 2 P35222 1 +Cell proliferation involved in heart morphogenesis 0.4640569395017659 0.6222392206541093 0.5337845799972127 1.0 0.8148862643802306 2 P35222 1 +Specification of animal organ identity 0.4640569395017659 0.6222392206541093 0.5337845799972127 1.0 0.8148862643802306 2 P35222 1 +Regulation of cellular response to insulin stimulus 0.4858519470326567 0.6219803016744291 0.5339548207386122 1.0 0.8149498311706612 14 Q9HCD5,Q06124,P18031,P05771,Q9BZF1,Q9Y5X3,P20020 7 +Nadp metabolic process 0.4850321211324712 0.6181523901856186 0.5364748902528529 1.0 0.8171551809700525 14 Q13423,P48735 2 +Regulation of filopodium assembly 0.4763028933733287 0.6178271818604922 0.5366892635627833 1.0 0.8171551809700525 8 P51114 1 +Tumor necrosis factor superfamily cytokine production 0.4867254481556114 0.6164086882253652 0.537624820577679 1.0 0.8179900331334338 16 P04792,O43823,Q06124,P15260 4 +Negative regulation of cell activation 0.4873305781393094 0.6151073460581927 0.5384838310239266 1.0 0.8191003449828668 17 P04083,P09601 2 +Sodium ion homeostasis 0.4732832590940576 0.6123915676528138 0.5402787194748626 1.0 0.8208725668585685 7 Q96PU5,Q9Y5X3 2 +Positive regulation of cardiac muscle cell proliferation 0.464222143111431 0.6119729407774134 0.5405556606439355 1.0 0.8208725668585685 3 Q16539,P06493 2 +Regulation of cardiac muscle cell proliferation 0.464222143111431 0.6119729407774134 0.5405556606439355 1.0 0.8208725668585685 3 Q16539,P06493 2 +Positive regulation of transcription from rna polymerase ii promoter in response to stress 0.464222143111425 0.6119729407773886 0.5405556606439519 1.0 0.8208725668585685 3 Q92616,P04637 2 +Regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.4642221431114235 0.6119729407773818 0.5405556606439563 1.0 0.8208725668585685 3 Q8IXJ6,P04637 2 +Morphogenesis of an endothelium 0.4642221431114203 0.6119729407773687 0.540555660643965 1.0 0.8208725668585685 3 P67870,P35222 2 +Endocrine system development 0.4747433086624574 0.6108266060377641 0.5413143775463074 1.0 0.8218277936058817 8 P04083,P30536 2 +Autophagy of mitochondrion 0.4893964634802675 0.6090698654812403 0.5424781307203022 1.0 0.8225360461040802 26 P12235,P50851,Q9UII2,O00429,P21796,P42858,O95140,P52789,P30536 9 +Plasma lipoprotein particle clearance 0.4759676543110957 0.6086412557668038 0.5427622524704434 1.0 0.8225360461040802 9 P09601,Q92945 2 +Positive regulation of cell growth 0.4860507102135696 0.6085552485410723 0.5428192748630682 1.0 0.8225360461040802 33 O95684,Q9GZP9,Q15418,Q9Y263,Q7L576,Q96K76,P51812 7 +Vasoconstriction 0.4657536680574036 0.6080146052738253 0.5431777871848298 1.0 0.8226858597969089 4 P20020 1 +Neuron projection regeneration 0.4765663928017835 0.604059481978712 0.545804096506916 1.0 0.8256769060788557 10 Q96G23,P30536 2 +Regulation of smoothened signaling pathway 0.4745200705794692 0.6021230114202601 0.5470922580460345 1.0 0.8267302938241391 9 Q7Z4L5 1 +Cardiac muscle cell proliferation 0.4643874643874662 0.6020321599733632 0.5471527303611234 1.0 0.8267302938241391 4 Q16539,P10644,P06493 3 +Regulation of histone h4 acetylation 0.4687356170733435 0.6007220046039256 0.5480251603561541 1.0 0.8276538229687675 6 O75844 1 +Positive regulation of cell cycle g1 s phase transition 0.4832240499413845 0.5998936033937006 0.5485771456971369 1.0 0.8282900577276047 16 P04083,Q96HY6,Q96DY7 3 +Viral protein processing 0.4703647488689225 0.5994032939063225 0.5489039809756595 1.0 0.8284382827322768 7 Q10472 1 +Protein polyglutamylation 0.4587188612099626 0.5990450487988689 0.549142844234626 1.0 0.8285519533130536 2 Q14679 1 +Cell part morphogenesis 0.2952786738442892 0.5981189735020177 0.549760551063412 1.0 0.8288918896238026 98 O00264,Q9NQC3,Q9UQB8,O60678,P61160,Q7L7X3,Q8TEY7,Q9Y4W6,Q14155,Q9BVA1,Q06124,Q9Y263,P35613,Q99829,Q02750,P42892,Q9UJX6,Q7L576,Q96PU5 19 +Face development 0.4700961426621703 0.5900608496064154 0.5551498550567375 1.0 0.8344806579630341 8 Q02750,O95470,Q06124 3 +Cdc42 protein signal transduction 0.4565836298932352 0.589820701463067 0.5553108623370564 1.0 0.8344806579630341 2 A0MZ66 1 +Endothelin receptor signaling pathway 0.4565836298932246 0.5898207014630226 0.5553108623370862 1.0 0.8344806579630341 2 P46109 1 +Glycerophospholipid biosynthetic process 0.4830568504855676 0.588376349695985 0.5562797086058568 1.0 0.8355402970929877 32 Q9Y217,Q96N66,Q9NPH0,Q9NTJ5,Q8NF37,P35790,Q9Y6K0,O43292,Q99943 9 +Regulation of phospholipid metabolic process 0.469359802335575 0.5867838746710118 0.5573488680884429 1.0 0.836749532593334 8 Q8WTV0,Q8NF37,O75874 3 +Response to interleukin 7 0.4707644440184617 0.5852772205855643 0.5583613291268295 1.0 0.8376738269552693 9 P31939,P67809 2 +Positive regulation of calcium ion transmembrane transport 0.4766765172932605 0.585080960149077 0.5584932805564167 1.0 0.8376738269552693 13 Q96GC9 1 +Mannosylation 0.4627830522809986 0.5846236966393564 0.5588007704901956 1.0 0.8379366972542285 5 Q9BT22 1 +Amyloid beta clearance 0.4750232243683772 0.5836340154591094 0.559466569748629 1.0 0.8381761883159788 12 Q16850 1 +Regulation of wound healing 0.4747416543385523 0.5823514253171849 0.5603299931675063 1.0 0.8391214585249785 12 O14936,P04083 2 +Negative regulation of establishment of protein localization to mitochondrion 0.4548042704626378 0.5821579485195618 0.5604602953172564 1.0 0.8391214585249785 2 P49257 1 +Response to lipid 0.2929372789848582 0.5817253844462483 0.5607516703041555 1.0 0.8392733431075657 124 P04083,O15118,P08670,P20020,P30536,O15228,O43823,Q9NXN4,Q9P0J0,O95831,Q96HY6,O15173,P40818,P11802,O75874,Q9Y263,Q14103,Q99829,Q9H7B4,Q86UE4,P51812,Q92769,Q8TB36,Q969T9,Q13126,Q15120,Q86X55,P16435,Q53EL6 29 +Cellular response to virus 0.4831622905235805 0.5806289825953772 0.5614905345523322 1.0 0.839586011670158 22 O75179,O60443,O43657 3 +Negative regulation of lipid biosynthetic process 0.4691654701743957 0.578134491461444 0.5631733220287272 1.0 0.8407136258412353 9 P05023,Q8NF37,O60678 3 +Negative regulation of ion transmembrane transport 0.4749996893503152 0.5773966766896695 0.5636715186911412 1.0 0.8410610816919618 13 Q96PU5,P21796 2 +Regulation of cell differentiation 0.2894797910939385 0.5744735165255397 0.5656474168732522 1.0 0.8430507841361203 187 P04083,Q9NQC3,Q9UQB8,Q9NX40,Q08J23,P55209,P01889,P30536,O75179,Q14155,Q06124,Q15418,Q8WUJ1,Q96JB5,Q99829,P51812,P67809,Q02750,O96005,Q7L576,P16435,Q96J02,Q9BYT8,P35611,Q9Y6C9,Q96G23,Q53EL6,Q8N4Q0 28 +Regulation of jnk cascade 0.4714358658198417 0.5739302310952691 0.5660150147370562 1.0 0.8433663645400247 11 Q53EL6,Q96J02 2 +Regulation of calcium ion transmembrane transport 0.4811679735347868 0.5729779015902934 0.5666596566136226 1.0 0.84393002208238 21 Q96GC9,P21796 2 +Organophosphate ester transport 0.4816889856953466 0.5718387719865682 0.5674312075585706 1.0 0.8445132616645659 23 P12235,Q9HC21,Q4KMQ2,Q8TB61,Q96GC9,Q9H2D1 6 +Postsynapse to nucleus signaling pathway 0.4523131672597872 0.5714680593536321 0.5676824056954914 1.0 0.8445132616645659 2 P52292 1 +Positive regulation of granulocyte chemotaxis 0.4543668070521217 0.5692546239125216 0.5691833557636781 1.0 0.8455027954698613 3 Q07021 1 +Positive regulation of neutrophil migration 0.4543668070521217 0.5692546239125216 0.5691833557636781 1.0 0.8455027954698613 3 Q07021 1 +Regulation of leukocyte mediated cytotoxicity 0.4607950285077873 0.5658648402734316 0.571485664445363 1.0 0.8471633086223158 6 Q9NUQ9,P01889 2 +Positive regulation of cell killing 0.4607950285077873 0.5658648402734316 0.571485664445363 1.0 0.8471633086223158 6 Q9NUQ9,P01889 2 +Cell cell signaling 0.2864809309044911 0.5642604608230164 0.57257688595671 1.0 0.8483562605348776 153 P50402,P04083,Q9UQB8,Q9UIQ6,Q13432,Q96K76,Q7Z4L5,P40818,P53985,Q13555,Q9BVA1,P16615,Q06124,Q9BPZ3,Q15418,O14936,Q14168,P43490,P51812,Q7L576 20 +Temperature homeostasis 0.4802068589393847 0.5627360423226581 0.5736146375752496 1.0 0.8494966016158814 25 Q9UIQ6 1 +Membrane raft organization 0.4632651988978769 0.559808020652997 0.5756103922320808 1.0 0.851375929194104 8 Q96S97,O15118 2 +Protein heterotetramerization 0.4591808121929085 0.558834102514081 0.5762749460394234 1.0 0.851375929194104 6 Q9Y285,Q9NSD9 2 +Negative regulation of transmembrane transport 0.4754055424830106 0.5588313404720949 0.5762768312356195 1.0 0.851375929194104 17 P31751,Q96PU5,P21796 3 +Regulation of superoxide metabolic process 0.453333618250334 0.5541056802688217 0.5795065229241902 1.0 0.8548559488805222 4 P00374 1 +Glycerolipid biosynthetic process 0.4719932459359055 0.5532698971266279 0.5800786108658034 1.0 0.855470830127204 37 Q8WTV0,Q92643,Q92604,Q99943,Q9Y217,Q8NCC3,Q96N66,Q9NPH0,Q9NTJ5,Q8NF37,Q10713,P42356,P35790,Q9Y6K0,O43292,O15228,O96017 17 +Protein folding in endoplasmic reticulum 0.4634381848066038 0.552701627721741 0.5804677385870354 1.0 0.8556464432254114 9 Q13217,Q8IXB1,P27824 3 +Postsynaptic signal transduction 0.4526353276353292 0.5511081962182323 0.5815595071616746 1.0 0.856687667964635 4 P04899,P46109,P52292 3 +Regulation of leukocyte degranulation 0.4550563510617829 0.5510787866929349 0.5815796666535995 1.0 0.856687667964635 5 P09601 1 +Axoneme assembly 0.4499822000712039 0.5504740373005846 0.5819942796114725 1.0 0.8570991749704628 3 A0AVF1,Q15555 2 +Positive regulation of g1 s transition of mitotic cell cycle 0.4673937938361039 0.5490832613488353 0.5829483118067325 1.0 0.8577944328758386 12 P04083,Q96DY7 2 +Vitamin transport 0.4588648816451837 0.5487992960669045 0.5831431934399736 1.0 0.8577944328758386 7 P38435,Q9HC21,Q9H2D1 3 +Protein maturation by protein folding 0.4561795230449507 0.5458142280628636 0.5851936419813741 1.0 0.8598126847289514 6 O76024 1 +Regulation of skeletal muscle tissue development 0.4536123430337586 0.5448593972337217 0.5858502233857485 1.0 0.8605778547972852 5 P16989 1 +Negative regulation of epithelial cell apoptotic process 0.4558607806895675 0.5444355681720351 0.5861417753979632 1.0 0.8608065888057689 6 P09601 1 +Positive regulation of meiotic cell cycle 0.4455516014234816 0.5426862578468638 0.5873458375114171 1.0 0.8613771285141982 2 Q8IXJ6 1 +Striated muscle cell proliferation 0.4527965799786195 0.5413530769762536 0.588264242936801 1.0 0.862524411728484 5 Q06330,Q16539,P10644,P06493 4 +Regulation of ossification 0.4620854452097619 0.5392144422325272 0.5897388962159682 1.0 0.8634842233039705 10 Q4KMQ2,Q06124,O75844 3 +Positive regulation of cellular amide metabolic process 0.4221428188938504 0.5358462268038792 0.5920648308204304 1.0 0.8654936177414226 58 P51116,Q9Y2R0,P15260,Q14011,Q13217,O60506,P16989,Q567V2,Q14103,Q07666,P51114,Q71RC2,P08670,Q9H074,Q6PKG0,P67809 16 +Organic hydroxy compound metabolic process 0.2906385655220393 0.5354402982686505 0.592345430468262 1.0 0.8657041035233802 99 Q9BQE5,P21964,Q15392,Q9BZF3,O15269,Q16850,P51648,O75874,Q8NBN7,P48449,P30837,Q9BY49,P53396,Q15800,P48735,O76054,P37268,P16435,Q14534 19 +Response to mitochondrial depolarisation 0.4555939676272624 0.5345861549437442 0.5929360594600468 1.0 0.8659681513708958 7 O95140,P52789,Q13501,Q9UII2 4 +Peptidyl tyrosine modification 0.4731999050793376 0.5332965953831595 0.5938282840781675 1.0 0.8664724467426541 31 Q02750,O95684,Q92769,Q06124,Q13432 5 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.4609211680021099 0.5269076476692629 0.5982577227824395 1.0 0.869930975051014 11 P04792,P15260 2 +Segmentation 0.457108086705285 0.5248834260813978 0.5996642317034016 1.0 0.8705778319139645 9 Q8N2A8 1 +Amino acid betaine metabolic process 0.4480805361229067 0.5211872647681182 0.6022363249127818 1.0 0.8733115768815328 5 P23786 1 +Biomineralization 0.4576563388382282 0.5196990352556671 0.603273359426145 1.0 0.8744152055543186 10 Q4KMQ2,P20020,O75844 3 +Myeloid leukocyte activation 0.4665133405232197 0.5175548999909031 0.6047688553488042 1.0 0.8755815024778095 17 P09601,P15260 2 +Chromosome organization involved in meiotic cell cycle 0.4653213575325555 0.5168172911726244 0.6052837084036515 1.0 0.8761267382717999 16 Q9BTX1,P46379 2 +Positive regulation of gene expression 0.286368276777149 0.5152710048583304 0.6063636575169988 1.0 0.8772891547226533 206 P04083,Q07021,Q96I24,Q96E39,Q01650,P62995,O14964,Q9UKG1,O60506,O96028,Q567V2,P08670,O95071,Q92804,Q9NUQ9,Q9Y2R0,Q14011,P16989,Q7Z4L5,Q96HY6,P04792,Q9NUD5,Q99729,P49755,P51116,Q06124,P15260,P04439,Q52LJ0,Q14103,Q07666,P51114,O75312,Q96FZ2,O75844,P67809,Q02750,Q15363,Q6PKG0,Q92769,Q13217,P35637,Q969T9,P09601,Q71RC2,P38159,Q9H074,Q99943 48 +Amp biosynthetic process 0.4562982003338033 0.5137472421321989 0.6074287179165747 1.0 0.8774278061174684 10 P55263,Q06203 2 +Regulation of myosin light chain phosphatase activity 0.438434163701055 0.5127833884433403 0.6081028509598079 1.0 0.8778013135608889 2 Q13464 1 +Platelet derived growth factor receptor signaling pathway 0.4524293320563327 0.512545668735906 0.6082691667723246 1.0 0.8778414278834481 8 P18031,O95470,Q06124 3 +Positive regulation of response to wounding 0.4538384975862126 0.510642522691654 0.6096013946091308 1.0 0.8781641367670066 9 P04083 1 +Skin epidermis development 0.4583492869279845 0.5087081883276964 0.6109567820088095 1.0 0.8793170855302808 12 O75844 1 +Spinal cord development 0.4514145040480669 0.5081686124859499 0.6113351007940948 1.0 0.8796473532117557 8 O43175 1 +Cellular hormone metabolic process 0.4618615280813918 0.5062859726991567 0.61265590884405 1.0 0.8811621639456979 15 Q8NBQ5,P42892,O95470,Q8NBN7,O60678,Q9Y394,P30536 7 +Negative regulation of translational elongation 0.4359430604982185 0.5024189951977648 0.6153728200887423 1.0 0.8837252171111536 2 P49458 1 +Protein localization to synapse 0.4519272850906199 0.50236024766065 0.6154141365175194 1.0 0.8837252171111536 9 Q9UQB8,Q14168,P04792 3 +Regulation of superoxide anion generation 0.4382342470630198 0.500911317667278 0.6164335370090361 1.0 0.8849885192628596 3 P04899,Q9NY61 2 +Dendritic cell chemotaxis 0.439745135090597 0.4964853349887192 0.6195520315044469 1.0 0.8874550686355516 4 Q4KMQ2 1 +Negative regulation of immune response 0.4645880132544178 0.4911317393288047 0.623333274270899 1.0 0.8908279926750009 22 P04083,P04439,Q9Y3Z3,P09601,P19474,P17931,Q9H000,P01889 8 +Hormone metabolic process 0.4657573997573531 0.4908209959634259 0.623553058684412 1.0 0.8908279926750009 28 Q8NBQ5,Q06124,P42892,O95470,Q8NBN7,O60678,Q969M3,Q9Y394,O75844,P05023,P16435,P30536 12 +Response to acid chemical 0.4616362632031093 0.4907587176264132 0.623597111309778 1.0 0.8908279926750009 18 Q9UQB8,Q15388,Q99729,O95831 4 +Positive regulation of neuron death 0.4555452724005474 0.4898223904911394 0.6242595851859041 1.0 0.891176614400332 13 O95831 1 +Regulation of cytoplasmic translational elongation 0.4320284697508918 0.4862440539402009 0.6267941401619259 1.0 0.8931851734216606 2 Q9H2P9 1 +Regulation of dna helicase activity 0.4339622641509496 0.4831842825760634 0.6289648942908521 1.0 0.8956038232231409 3 P49736,P33993 2 +Regulation of organic acid transport 0.4492356591868608 0.4830549095943512 0.6290567488032508 1.0 0.8956038232231409 10 P31751,Q15041 2 +Regulation of protein localization to chromatin 0.433606265574944 0.4817145933234608 0.6300087077910774 1.0 0.8959526887954031 3 Q9BYW2,Q7Z5K2 2 +Stress granule disassembly 0.4336062655749302 0.4817145933234033 0.6300087077911183 1.0 0.8959526887954031 3 P33176,Q07866 2 +Cytokine production involved in immune response 0.4488744457459416 0.4814971847650753 0.630163180103178 1.0 0.8959712973555842 10 P09601,Q01650 2 +Negative regulation of cell cycle g2 m phase transition 0.4574828232135307 0.4812604070427165 0.6303314329172114 1.0 0.8960094864056458 16 Q7L7X3,Q96K76,Q96JB5,Q9Y619 4 +Regulation of smooth muscle cell differentiation 0.4403759916002457 0.4784747683849709 0.6323123286154391 1.0 0.8980549329465027 6 Q53EL6 1 +Cellular response to unfolded protein 0.4631851074168841 0.478240613005525 0.6324789594035414 1.0 0.8980549329465027 26 Q15363,P18031,Q9GZP9,Q9Y4P3,Q96JB5,O76024,P48723,Q96HY6,Q9BUN8 9 +Positive regulation of canonical wnt signaling pathway 0.4554486610074781 0.4775008200456466 0.6330055370419174 1.0 0.8984000197613955 15 Q96K76,Q7Z4L5 2 +Lipopolysaccharide mediated signaling pathway 0.4399465269341774 0.476675560418763 0.6335931685654981 1.0 0.8986302393016028 6 Q86UE4 1 +Negative regulation of peptidase activity 0.460210695425294 0.4746598279622741 0.6350294555061222 1.0 0.900264353365167 34 P04080,Q15418,Q96K76,P51812,Q15392,P30086 6 +Negative regulation of secretion 0.4588406583766653 0.4738587496902223 0.6356006366221614 1.0 0.900469759506961 19 Q16850,P04083,P09601 3 +Positive regulation of dna dependent dna replication 0.4341168091168059 0.4730896506117557 0.63614922013286 1.0 0.9007740880165256 4 O95785,P24941,Q9UJZ1 3 +Positive regulation of mononuclear cell migration 0.4411651997292675 0.4729597662482163 0.6362418838507131 1.0 0.9007740880165256 7 P17931,Q4KMQ2,Q07021 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.4385096252497076 0.4706684029241632 0.6378775516984629 1.0 0.9022980704132574 6 O95140,P52789 2 +Copii coated vesicle budding 0.4587647091974368 0.4698145955675106 0.6384874856532976 1.0 0.9025932563992882 20 P49755,Q9HCU5,Q15363,P53992,Q5JRA6,Q15437,O15027,P55735 8 +Metal ion export 0.4404047276125667 0.4697637175189762 0.6385238391096748 1.0 0.9025932563992882 7 P05023,Q4KMQ2,P20020 3 +Positive regulation of leukocyte proliferation 0.4463276350895552 0.4631696597499083 0.6432427618921652 1.0 0.9076440396594636 11 P30825 1 +Protein o linked glycosylation 0.4477724282272105 0.4623910077148832 0.643800946682664 1.0 0.9079964462278308 12 O60502 1 +Peptidyl proline modification 0.4598800428180812 0.4621682424393661 0.6439606752724145 1.0 0.9079964462278308 26 Q96AY3,Q9BV86,P62942,O75718,Q32P28,P13674 6 +Regulation of lipid transport 0.4515340347054293 0.460116933813737 0.6454322899373133 1.0 0.9087101580388256 15 P31751,Q9BZF3,O15260,Q06124 4 +Nucleobase containing compound transport 0.2854371660607742 0.4594101884362598 0.6459396331998342 1.0 0.9087559155744316 105 P12235,Q96ST2,Q08J23,P51991,Q9H2D1,P22626,Q9ULX6,Q5JVF3,Q8NFH4,Q15388,Q9HC21,L0R6Q1,Q07666,Q8TB61,Q8N1F7,Q8TD16,P12236,P67809,Q9BTX1,Q9UBU9,Q9BW27,Q16629,P55735,Q12769,Q07955,Q9Y6M1,Q92945 27 +Nuclear transcribed mrna catabolic process deadenylation dependent decay 0.459169991593614 0.4587294309892368 0.6464284765828061 1.0 0.9087559155744316 26 Q969T7,Q9NQT4,O60506,Q14103,Q96B26,Q9H074,P67809 7 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.4469129985844771 0.4586735322585734 0.6464686235457688 1.0 0.9087559155744316 12 Q96RU2,P46379 2 +Cellular response to chemical stress 0.3653682893748332 0.4571076390352929 0.6475936798507465 1.0 0.9089142163607448 70 Q9NR28,Q92769,P04083,P16615,Q8TED1,O43813,Q07820,Q9BPX6,Q15233,P16989,P09601,P49327,O95831,Q99720,P04792,P09493,P00374,P30536 18 +Meiotic chromosome segregation 0.4560035726007493 0.4570945212610508 0.6476031080589801 1.0 0.9089142163607448 20 Q9BTX1,Q92791,P61160,Q15003,Q9BZD4,Q92889,O60216,O94901,P46379 9 +2fe 2s cluster assembly 0.427554289782839 0.4569149055117011 0.6477322099358096 1.0 0.9089142163607448 3 O76003,Q86SX6 2 +Positive regulation of lipid metabolic process 0.4507951724325124 0.4568524752899087 0.6477770852018683 1.0 0.9089142163607448 15 Q8WTV0,Q13131,Q92604,P04083,Q9UJZ1,P31751,P16435 7 +Regulation of translational elongation 0.4324902030637603 0.4559026919761053 0.6484599536526534 1.0 0.9089474290273388 5 P63241,P38919,P49458,Q9H2P9 4 +Embryo implantation 0.4428166958527796 0.4555568993257826 0.6487086426574149 1.0 0.9089474290273388 10 Q96GC9,P35613 2 +Midbrain development 0.4528571121907776 0.4554905195001834 0.6487563865378969 1.0 0.9089474290273388 17 O14949,O15027 2 +Smooth muscle cell differentiation 0.4368258623643252 0.4547976355967886 0.6492548314238011 1.0 0.9091053300036176 7 Q53EL6 1 +Regulation of entry of bacterium into host cell 0.423843416370098 0.4528900432274421 0.6506279209356001 1.0 0.9103619198429892 2 Q9BTY2 1 +Entry of bacterium into host cell 0.423843416370098 0.4528900432274421 0.6506279209356001 1.0 0.9103619198429892 2 Q9BTY2 1 +Endochondral bone morphogenesis 0.4316451265675596 0.4524293805123862 0.6509596851007431 1.0 0.910625060592364 5 O75844 1 +Release of cytochrome c from mitochondria 0.4482994784613983 0.451769900204883 0.6514347558327827 1.0 0.9109270335144006 14 Q9H3K2,O00429,Q96A26,Q3ZCQ8,O60313 5 +Negative regulation of proteolysis 0.4132695626006432 0.4512985887324192 0.6517743618690182 1.0 0.911094085404604 57 P04080,Q15418,Q96K76,Q96HY6,Q96KC8,P51812,Q15392,P30086,P46379 9 +Response to caffeine 0.4261386547591291 0.4511657923746557 0.65187006205215 1.0 0.911094085404604 3 Q92769 1 +Cellular response to retinoic acid 0.4308846198812466 0.4493097704151044 0.6532082105881116 1.0 0.9123606855844972 5 Q9P0J0 1 +Hindbrain development 0.4566394004357549 0.4483405760521506 0.6539074210387377 1.0 0.9131254368287188 31 Q02750,O14949,Q06124,P31939,Q14103,O95456,Q7Z4L5,O15228 8 +Gmp metabolic process 0.4474341956129714 0.4479925319655543 0.6541585863092303 1.0 0.9131254368287188 14 O14936,Q14168,P55263,Q06203 4 +Regulation of regulated secretory pathway 0.4509325685382287 0.4468864368101141 0.6549570574095438 1.0 0.9131254368287188 17 P16615,Q15042,P09601,O14936,P51809 5 +Positive regulation of phagocytosis 0.4346490829597222 0.4457566244362675 0.6557730571260059 1.0 0.9131254368287188 7 Q4KMQ2 1 +Cardiolipin acyl chain remodeling 0.4202846975089009 0.4385962341938908 0.6609541261695344 1.0 0.9175354872752308 2 Q6UWP7 1 +Regulation of phospholipase activity 0.4369307888123361 0.4385389170655959 0.6609956653624938 1.0 0.9175354872752308 9 P04083 1 +Erbb signaling pathway 0.452612784712589 0.4381121227622955 0.6613050069669764 1.0 0.9175354872752308 21 Q9NQC3,Q06124 2 +Positive regulation of ion transport 0.4462823666144521 0.4379788347694998 0.6614016263016025 1.0 0.9175354872752308 41 P51809,Q9Y4C2,P42858,O14936,O43865,O76024,Q4KMQ2,Q15041,Q96GC9,P20020,P30536 11 +Gliogenesis 0.434178933860828 0.4373207366956532 0.661878758660283 1.0 0.9177955565930446 48 Q02750,P04083,Q06124,P15260,Q96N66,Q9NQC3,O43175,Q7Z4L5,P08670,P31751,Q96G23,P30536 12 +Cytoplasmic sequestering of nf kappab 0.4252136752136697 0.4367051092252417 0.6623252234380086 1.0 0.9182137258645068 4 Q9UN86,O60826,O75832 3 +Glial cell development 0.4478132693744825 0.4330213051671343 0.6649992919879295 1.0 0.9213162469015104 17 P15260,P08670,O43175 3 +Neuron projection guidance 0.4477671724461665 0.4328171663038868 0.665147601231598 1.0 0.9213202948644016 17 Q9BVA1,Q8TEY7,O00264,P42892,Q7L576,P35613 6 +Response to corticosteroid 0.453330626874236 0.4319044541020125 0.6658108573994779 1.0 0.9220374570237088 25 P04083,O95831,Q99829,Q9H7B4,P40818 5 +Insulin metabolic process 0.4211463154147432 0.4310549560543462 0.6664284116364707 1.0 0.922655210043376 3 Q96HE7,Q969M3 2 +Protein localization to nuclear envelope 0.4331092318594765 0.4308441825267811 0.6665816713732684 1.0 0.922655210043376 8 Q9BZF1 1 +Neurogenesis 0.2775512172929055 0.4306900751338706 0.6666937362772005 1.0 0.922655210043376 231 P04083,O00264,Q9NZJ7,Q9NQC3,Q9UQB8,Q8WWV3,O60678,P61160,Q7L7X3,P55209,P08670,P30536,Q8TEY7,Q9Y4W6,Q969G3,Q9BW83,Q7Z4L5,O60443,Q13555,Q9BVA1,Q06124,P15260,Q96N66,Q8NBN7,Q9Y263,Q8WUJ1,Q96JB5,P35613,O75312,Q99829,Q8NHS3,P54802,Q02750,O14949,Q92769,O43175,P42892,O75306,Q86VR2,Q9UJX6,Q9UBS4,Q7L576,Q32P28,Q96PU5,Q86X55,O14976,P31751,Q96G23 48 +Cell activation 0.2825211043230053 0.4286250235762943 0.6681961318625427 1.0 0.9245325082124308 116 P04083,O96005,P15260,P04792,Q15418,P09601,Q9UQ84,Q96L92,P30825,P46379 10 +Cytoplasmic sequestering of transcription factor 0.4253651585322332 0.4268467820582315 0.6694909296097908 1.0 0.9248767680937352 5 Q9UN86,O60826,P30626,O75832 4 +Regulation of nucleotide biosynthetic process 0.4267951528214108 0.4224562986289473 0.6726919923636279 1.0 0.9281186927081012 6 Q15120 1 +Organelle inheritance 0.4285098712365574 0.4205208436101724 0.6741050058693809 1.0 0.9296634215874358 7 Q13190 1 +Positive regulation of response to cytokine stimulus 0.4342851174838195 0.4196443518491132 0.6747452830843974 1.0 0.9303439640787264 10 Q99829 1 +Positive regulation of gliogenesis 0.4281384699538196 0.4190069875595945 0.675211025628019 1.0 0.9305490872513116 7 Q92769,P30536 2 +Negative regulation by host of viral transcription 0.4198717948717976 0.4152675672161126 0.6779460409089813 1.0 0.9329025625574052 4 Q13148,Q13547,P52926 3 +Purine nucleoside metabolic process 0.431284939352845 0.4150939953099824 0.6780730950196321 1.0 0.9329025625574052 9 O60725 1 +Negative regulation of cytokine production 0.44955296044626 0.4140844861804231 0.6788122340041098 1.0 0.9337167629442248 25 O43823,P04083,Q07021,P09601,Q96J02,P20020,Q53EL6,P30536 8 +Mechanoreceptor differentiation 0.4306833501637843 0.4126160657171631 0.6798879286722967 1.0 0.934503662934245 9 O60443,Q9BW83 2 +Protein k63 linked ubiquitination 0.4372986408555873 0.4107893428717223 0.681227008309595 1.0 0.9348319779412227 13 O95376,Q9Y263,P19474,Q96J02,O95071,Q96FW1 6 +Regulation of neurotransmitter transport 0.4384235138673029 0.4091197685818544 0.6824517694769141 1.0 0.935218947841816 14 P16615,Q15042,O14936,P35080,P05771 5 +Steroid hormone biosynthetic process 0.4229309532801825 0.4068685970766817 0.684104501341694 1.0 0.93652413588298 6 Q8NBQ5,P30536 2 +Negative regulation of hydrolase activity 0.4124076373657305 0.4064371999358186 0.6844213912614587 1.0 0.9367555845407914 55 Q15363,P04083,P62942,P36404,P04080,Q15418,P16435,Q96K76,Q4VCS5,Q15041,P51812,Q15392,P30086 13 +Positive regulation of epithelial cell proliferation 0.4397463973241177 0.4029963396109945 0.6869509172718575 1.0 0.9394498307283444 16 Q9NQC3 1 +Interferon gamma production 0.4261876668034546 0.4024906949749748 0.6873229350300729 1.0 0.9395093699925738 8 Q9NUQ9,P04439,Q01650 3 +Intrinsic apoptotic signaling pathway in response to oxidative stress 0.4327005740646482 0.3983014411456912 0.6904079982877154 1.0 0.942410083932124 12 Q9NR28,P04792 2 +Aromatic amino acid family metabolic process 0.4151485984413973 0.3965745504156064 0.6916812226973552 1.0 0.9428229529432436 4 Q92947 1 +Regulation of plasma lipoprotein particle levels 0.4303017894934029 0.3955702603997499 0.6924220800170338 1.0 0.943099899547518 11 P09601,Q92945 2 +T cell homeostasis 0.4148110785664702 0.3952484697372018 0.6926595249127554 1.0 0.943099899547518 4 O95067 1 +Regulation of membrane tubulation 0.4092526690391395 0.3951504003360643 0.6927318949782009 1.0 0.943099899547518 2 P50570 1 +Xmp metabolic process 0.4221089567796811 0.3946437658738319 0.6931058092483635 1.0 0.9431845857556824 7 Q06203 1 +Negative regulation of atp dependent activity 0.4220526837662238 0.394418320592187 0.6932722199351111 1.0 0.9431845857556824 7 P49736,Q15070 2 +Xenobiotic metabolic process 0.4299971918479647 0.3943125100068758 0.6933503283011895 1.0 0.9431845857556824 11 O43169,P07099 2 +Negative regulation of apoptotic signaling pathway 0.4077078399365722 0.3937443397399026 0.6937698018944451 1.0 0.9431845857556824 56 Q07820,P18031,Q15233,P61289,P42858,O95881,P16989,P09601,Q96K76,O76024,Q9P0J0,P45880,P04792,O60313 14 +Positive regulation of anoikis 0.4104239414868376 0.3887756154483691 0.697442140629075 1.0 0.9453317596914113 3 O96017 1 +Regulation of execution phase of apoptosis 0.4183891660726939 0.3887617466660159 0.6974524008928058 1.0 0.9453317596914113 6 O00273,Q8IXJ6,Q13625,P63167,P04637 5 +Positive regulation of proteolysis 0.324680487770229 0.3885527101236592 0.6976070549147757 1.0 0.9453317596914113 77 Q9NR28,Q92769,Q9BXK5,Q9NZJ7,Q4ZIN3,P61289,Q96A26,Q96JB5,P49327,Q9P0J0,O95831,Q96HY6,Q9H000,O43765,P46379 15 +Maternal placenta development 0.4156797396749738 0.3882272444576324 0.6978478731002717 1.0 0.9453317596914113 5 Q15363 1 +Atp biosynthetic process 0.4385627167872536 0.3875107518909998 0.6983781266680853 1.0 0.9458478710612644 18 O75964,P00403,P24539,P06576,P36542,P56134,Q9UJS0 7 +Negative regulation of cell projection organization 0.4435444476570993 0.3860762046574233 0.6994402321691702 1.0 0.946881596081186 25 Q92769,Q9NQC3,P35080,Q86X55,P08670,Q96G23 6 +Regulation of plasma membrane organization 0.4093983624065531 0.3848006394436387 0.7003851253314626 1.0 0.9474516855607036 3 P35579,P50570 2 +Regulation of striated muscle cell differentiation 0.4214272213390463 0.3833019294476587 0.7014959088162014 1.0 0.9478489027557884 8 Q9BYT8 1 +Fibroblast proliferation 0.4322473878566411 0.3829925749920385 0.7017252694214782 1.0 0.9478489027557884 14 P50402,O75844 2 +Cell junction maintenance 0.419127305257477 0.3827491819109291 0.7019057442555461 1.0 0.9478489027557884 7 Q96S97 1 +Molting cycle 0.4305273445655933 0.3823620250387734 0.7021928539095392 1.0 0.9478489027557884 13 O75844 1 +Maintenance of protein localization in organelle 0.4304119087875336 0.3818820159939088 0.7025488803386128 1.0 0.9478489027557884 13 O43292,P36404,P52789,P30536 4 +Negative regulation of response to external stimulus 0.4383479723206849 0.3817232609532589 0.7026666445490202 1.0 0.9478489027557884 39 O43657,Q9Y3Z3,O14936,P80303,Q96J02,P01889,Q96G23 7 +Negative regulation of ion transport 0.433087629524702 0.3803367990800345 0.7036954225839838 1.0 0.948791041045682 15 Q96PU5,P21796 2 +Locomotor rhythm 0.4079253070032187 0.3791132759493508 0.704603748116158 1.0 0.9488885581738976 3 P54802 1 +Regulation of mitochondrial membrane permeability 0.4296782796598217 0.3788351227804693 0.7048103037629039 1.0 0.9488885581738976 13 P45880,P12235 2 +Response to redox state 0.4049822064056911 0.3787058514236154 0.7049063076654658 1.0 0.9488885581738976 2 Q8IXJ6 1 +I kappab kinase nf kappab signaling 0.4355231728807138 0.3786259471715396 0.7049656512360281 1.0 0.9488885581738976 41 Q9P035,O43657,P09601,Q8TB61,Q96HY6,Q99829,Q86UE4,P04792 8 +Response to arsenic containing substance 0.4242228451562738 0.378306884915202 0.7052026314078321 1.0 0.94900596203683 10 P36551,P09601 2 +De novo amp biosynthetic process 0.4179199691330114 0.377962613149072 0.7054583677658188 1.0 0.9491485512806782 7 Q06203 1 +Response to x ray 0.4258080685860987 0.3771245433538998 0.7060810525524801 1.0 0.9494393076503196 11 P04083 1 +Triglyceride biosynthetic process 0.4096917504913001 0.3752993752065143 0.7074378307642579 1.0 0.950314276713616 4 Q92604 1 +Camera type eye development 0.4406991862652044 0.3751554599870038 0.7075448528489279 1.0 0.950314276713616 24 Q8NF37,Q8NBN7,Q15042,Q15293,P08670,P20020,P54802 7 +Phospholipid dephosphorylation 0.4112466776004933 0.3709123739521913 0.7107027984593026 1.0 0.9508041389430916 5 Q9Y217 1 +Activation of phospholipase c activity 0.402846975088962 0.370566008251056 0.710960803733083 1.0 0.9508041389430916 2 Q99623 1 +Regulation of phospholipase c activity 0.402846975088962 0.370566008251056 0.710960803733083 1.0 0.9508041389430916 2 Q99623 1 +Activation of protein kinase c activity 0.402846975088962 0.370566008251056 0.710960803733083 1.0 0.9508041389430916 2 Q99623 1 +Regulation of transmembrane transport 0.374983271507903 0.3703266342591295 0.7111391310205293 1.0 0.9508041389430916 65 Q06124,P62942,P21796,P42858,Q9Y4C2,O43865,Q4KMQ2,Q96PU5,P52789,Q15041,Q96GC9,P31751,O75844 13 +Golgi organization 0.4248558982370272 0.3701687854211608 0.7112567328763935 1.0 0.9508041389430916 47 P49755,Q02750,Q9BVK6,Q15363,Q13190,Q9Y3A6,O15027,P42858,Q12907,Q9P2W9,Q14155,Q9Y3B3,O15260,Q96GC9 14 +Cellular monovalent inorganic cation homeostasis 0.4395778559912832 0.3700568488122105 0.7113401329855131 1.0 0.9508041389430916 24 Q8N511,Q9Y487 2 +Polyadenylation dependent snorna 3 end processing 0.4129788175420763 0.367507917901521 0.7132401868032097 1.0 0.9519516271596432 6 Q9NQT4 1 +Cellular response to hormone stimulus 0.2786603266274149 0.3671494431617635 0.7135075482990223 1.0 0.9519516271596432 109 P04083,P18031,Q9UQB8,P42785,Q9UKG1,O60343,O15118,O43865,P05023,P20020,O43823,Q6RW13,O95831,Q96HY6,O15173,P40818,Q9Y5X3,Q9BZF1,P11802,Q06124,P43490,Q9H7B4,Q969T9,Q7L576,Q86X55,P31751,P16435 27 +Positive regulation of vacuole organization 0.4096900605628741 0.3648890044485089 0.715194262441982 1.0 0.9523670579473122 5 Q9H2M9,P07355,Q15042,Q6UWE0 4 +Cellular response to molecule of bacterial origin 0.4388222623006361 0.3643692811847059 0.7155822712019564 1.0 0.9523670579473122 25 Q8WTV0,Q9NUQ9,O43823,P11802,Q86UE4,Q9Y263,P08670,Q53EL6,P30536 9 +Bile acid metabolic process 0.4187198466227905 0.3641987892103576 0.7157095710665011 1.0 0.9523670579473122 9 Q9BZF3 1 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.4066295162048866 0.3635176065204198 0.7162182630911704 1.0 0.9523670579473122 4 Q9NPA0 1 +Tor signaling 0.4304264125419613 0.363258324313145 0.716411922368031 1.0 0.9523670579473122 16 Q8NHS3,P55735,Q6PKG0,O75844 4 +Positive regulation of muscle tissue development 0.4037023851904662 0.3629553334735254 0.7166382509695359 1.0 0.9523670579473122 3 Q13131,P35222 2 +Positive regulation of skeletal muscle tissue development 0.4037023851904662 0.3629553334735254 0.7166382509695359 1.0 0.9523670579473122 3 Q13131,P35222 2 +Protein localization to membrane raft 0.403702385190462 0.3629553334735094 0.7166382509695479 1.0 0.9523670579473122 3 Q14254,P05026 2 +Regulation of toll like receptor 4 signaling pathway 0.4037023851904546 0.3629553334734808 0.7166382509695692 1.0 0.9523670579473122 3 Q06481,Q9UKG1 2 +Toll like receptor 4 signaling pathway 0.4037023851904546 0.3629553334734808 0.7166382509695692 1.0 0.9523670579473122 3 Q06481,Q9UKG1 2 +Microtubule based process 0.2778771627052498 0.361558867392199 0.7176817069802437 1.0 0.9532485804095168 195 Q96P70,P36404,P61160,P33176,Q7L7X3,Q96DB5,Q9BZD4,Q9BSJ2,Q14679,O95067,O14530,A0AVF1,Q9Y6A5,O95684,Q9Y678,Q8TEY7,Q9BV86,O94927,P29372,Q13561,Q9BW83,P68371,Q8ND56,Q7Z4L5,Q96PK6,Q14155,P61758,P04792,O60313,O94901,P53985,O43633,P07437,Q9BVA1,Q13131,Q15813,Q9HBM1,Q92572,Q9BUF5,Q15004,P42858,Q14168,Q15005,O75312,Q8TD16,O75935,O96017,Q5SNT2,Q9UJX6,Q15058,Q9NRG9,Q9Y2T2 52 +Demethylation 0.4280922270775377 0.3594005773332855 0.7192954428906226 1.0 0.95444029489743 15 Q16850,Q8NB78 2 +Hippo signaling 0.4052685957925772 0.3583189347957758 0.720104649663788 1.0 0.95480260303115 4 Q4VCS5 1 +Interleukin 12 production 0.4126265177022614 0.3571852988570128 0.7209530907956512 1.0 0.95480260303115 7 P01889 1 +Negative regulation of phosphatase activity 0.4098631062130805 0.3554304940602202 0.7222671073266236 1.0 0.9552557468285424 6 P62942 1 +Positive regulation of translation 0.4019122741455765 0.3554160006111106 0.7222779635941647 1.0 0.9552557468285424 56 P51116,Q9Y2R0,Q14011,Q13217,O60506,P16989,Q567V2,Q14103,Q07666,P51114,Q71RC2,P08670,Q9H074,Q6PKG0,P67809 15 +Mitochondrial fusion 0.4237825216425586 0.3545869251029758 0.7228990727478963 1.0 0.9553725597504524 13 Q9Y6C9,Q8TB36,O60313,Q8N2A8 4 +Lymphocyte homeostasis 0.4067179506323374 0.3534722178800806 0.7237344531582577 1.0 0.9558647110233424 5 O95067 1 +Regulation of cell killing 0.4115709503908074 0.3530837421057742 0.7240256608666629 1.0 0.9558647110233424 7 Q9NUQ9,P01889 2 +Monovalent inorganic cation homeostasis 0.4366461556203577 0.352543348646533 0.7244308149470937 1.0 0.956200390401944 26 Q93050,Q8N511,Q96PU5,P06576,P05023,Q9Y5X3,Q9Y487 7 +Terpenoid metabolic process 0.4277757521212933 0.3521500671337645 0.7247257219945573 1.0 0.9563904415409225 16 Q9BY49,P51648,Q8NBN7,P48449,P37268 5 +Synaptic signaling 0.3304734390892216 0.3513012296545683 0.725362372531249 1.0 0.9568320888281692 75 Q9BVA1,P16615,Q9UQB8,Q9BPZ3,Q15418,Q13432,O14936,P40818,P51812 9 +Cellular response to vitamin d 0.4029605264096672 0.3495558438337565 0.726672054175856 1.0 0.9575021248102068 4 Q8TB36 1 +Cellular response to reactive oxygen species 0.4354903938413908 0.3492236564179027 0.7269214076238435 1.0 0.9575021248102068 25 Q99720,O95831 2 +Membrane lipid metabolic process 0.4354081049782097 0.3446149000749685 0.7303839026079579 1.0 0.958832220029948 32 O15269,Q9P035,Q9NZJ7,O95470,Q06136,Q9NZ01,Q8NBX0,Q96G23,O43292 9 +Organelle disassembly 0.4311150181853945 0.3435250674060923 0.7312034858548091 1.0 0.9589479490608288 39 P12235,P50851,Q13190,P21796,P42858,Q86VR2,P33176,P52789,Q96HY6,P30536 10 +N terminal protein amino acid acetylation 0.4038982285243657 0.3427448033582274 0.7317904538046085 1.0 0.959037570371288 5 Q86UY6 1 +Export across plasma membrane 0.4111318913616212 0.342736029423771 0.7317970550510327 1.0 0.959037570371288 8 P05023,Q4KMQ2,P20020 3 +Regulation of t cell proliferation 0.4250199693504928 0.340696633731874 0.7333319731181898 1.0 0.9601319107856032 16 P04083,P04439,Q92990,P17931,Q96J02,P30825 6 +Positive regulation of dendrite morphogenesis 0.4127200167873022 0.3405716344402014 0.7334260865626716 1.0 0.9601319107856032 9 Q9UQB8,Q9UJX6 2 +Defense response 0.276454922413164 0.3400480266177399 0.7338203606105751 1.0 0.9601940171772072 190 P04083,P42785,P60900,O60506,Q9BQE5,P08670,P01889,P10321,O43823,O43657,P68371,O75179,Q9NZ08,Q9NUD5,Q9BPX6,P07437,Q06124,P15260,Q9Y3Z3,Q9NQT4,Q9Y263,Q4KMQ2,O75844,P51809,Q9NVI7,Q13217,P09601,Q96J02,Q53EL6 29 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.414083028116216 0.3378773245831193 0.7354556360576954 1.0 0.9611896588210188 10 Q96K76 1 +Rna decapping 0.3995726495726472 0.33681783817049 0.7362542250923936 1.0 0.9611896588210188 4 Q9UIV1,Q9BQG2,Q96C86 3 +Methylguanosine cap decapping 0.3995726495726472 0.33681783817049 0.7362542250923936 1.0 0.9611896588210188 4 Q9UIV1,Q9BQG2,Q96C86 3 +De novo protein folding 0.4266618736523939 0.3366225973261806 0.7364014192166712 1.0 0.9611896588210188 18 Q99543,P62942,P48723 3 +Response to reactive oxygen species 0.4337354333490019 0.3357968350327284 0.7370240770148766 1.0 0.9616062540752056 31 Q99720,O95831,P09601 3 +Regionalization 0.4273965095667515 0.3348050007689302 0.7377721879520784 1.0 0.962140701388722 19 Q15363,Q7Z4L5,Q8N2A8 3 +Cellular response to insulin like growth factor stimulus 0.3932384341637053 0.3346499085606685 0.7378891918493276 1.0 0.962140701388722 2 P08069 1 +Regulation of natural killer cell mediated immunity 0.398526538003466 0.3329151693396317 0.7391983185071984 1.0 0.9630302262225428 4 P01889 1 +Plasma membrane to endosome transport 0.3985042735042724 0.3328322672577525 0.7392608997980905 1.0 0.9630302262225428 4 Q99523,P61020,P51148 3 +Second messenger mediated signaling 0.4279027189088127 0.3324101549417105 0.7395795715671978 1.0 0.9631309510410492 20 P16615,O75844 2 +Innate immune response 0.2758834383610171 0.3322340482982432 0.7397125356977727 1.0 0.9631309510410492 114 P04083,Q07021,P18031,Q15233,Q9UKG1,O60506,P61160,P08670,P01889,P10321,O43823,P68371,O75179,Q96PK6,Q9NZ08,Q9NUD5,P07437,Q06124,P04439,Q9Y3Z3,P51809,Q9NVI7,Q96J02 23 +Immune response regulating cell surface receptor signaling pathway 0.4316027163810996 0.3317374348423688 0.7400875309407955 1.0 0.9633979346512128 25 Q96IZ0,P04439,Q9UKG1,Q9H4A3,Q07666,P17931,P05771,Q9NR50,P46379 9 +Negative regulation of protein secretion 0.4124680778873602 0.3315598491595439 0.7402216417574174 1.0 0.9633979346512128 10 Q16850 1 +Chromosome movement towards spindle pole 0.3974358974358962 0.3288619846599569 0.7422600093469507 1.0 0.964489450812388 4 Q15398,P61158,P61160 3 +Regulation of cell cycle phase transition 0.2750553726700556 0.3288383164003005 0.7422778998914339 1.0 0.964489450812388 101 P04083,P61289,Q9UKG1,Q08J23,Q7L7X3,Q9Y619,Q96DY7,Q9UJX3,Q5JVF3,Q96K76,O75179,Q96HY6,O60216,Q8IXJ6,P11802,Q06124,Q96JB5,Q8N6R0,Q9NXR7,P49454,Q96RU2,O96017,Q9UJX4,Q15058 24 +Mitochondrial fission 0.4095586154539711 0.3283098062710423 0.7426774304088279 1.0 0.9647439153038666 9 Q9NUQ9,O60313,Q8TB36 3 +Negative regulation of stress activated protein kinase signaling cascade 0.4092737723848605 0.327211553221674 0.7435078832388244 1.0 0.9653714376637806 9 Q96J02 1 +Sprouting angiogenesis 0.4128590809732301 0.3253650399659786 0.7449048113622272 1.0 0.9664793746482552 11 P09601 1 +Cellular response to vitamin 0.3989336131295904 0.3241112115755861 0.7458538390990994 1.0 0.9665151043455804 5 Q8TB36 1 +Ventricular cardiac muscle tissue development 0.4039698795069632 0.3239750222636807 0.745956944584365 1.0 0.9665151043455804 7 P62942,O75844 2 +Regulation of intrinsic apoptotic signaling pathway 0.4183799654066268 0.3231013797969826 0.7466184653336436 1.0 0.9666433083882456 46 P61978,Q07820,P18031,Q15233,O95881,P16989,Q96K76,O76024,Q9P0J0,P45880,P04792,O60313,O60443 13 +Mature ribosome assembly 0.3957982465839896 0.3228061621047464 0.7468420459612681 1.0 0.9666433083882456 4 Q7Z2Z2,Q07021 2 +Regulation of synapse structure or activity 0.4304845722412758 0.3215569377490833 0.7477883711258375 1.0 0.9666433083882456 28 Q9UQB8,P07437,O00264 3 +Protein deneddylation 0.4055970672584169 0.3214894995754545 0.7478394684069714 1.0 0.9666433083882456 8 Q92905,Q7L5N1,Q9BT78,Q99627 4 +Positive regulation of actin filament polymerization 0.407747327301226 0.321344816269001 0.7479490973493286 1.0 0.9666433083882456 9 Q9UQB8 1 +Vascular associated smooth muscle cell apoptotic process 0.3952275904792507 0.3207045544051751 0.748434295547088 1.0 0.9666433083882456 4 Q53EL6 1 +Regulation of mrna catabolic process 0.3317015954642285 0.3205320135919358 0.7485650661167602 1.0 0.9666433083882456 74 Q969T7,O60506,P08670,Q92804,Q14011,P16989,Q5JVF3,Q99729,Q5PRF9,P51116,Q9NQT4,Q14103,P51114,Q6PKG0,P67809,P07910,P35637,Q96B26,Q9H074,Q92945 20 +Autophagosome maturation 0.4239125702839919 0.3201415585954922 0.7488610229263257 1.0 0.9666433083882456 19 Q8NHS3,P16615,Q96GC9 3 +Regulation of protein phosphorylation 0.2717288882828195 0.3197974647999443 0.7491218695746686 1.0 0.9666433083882456 144 Q9Y4R8,P18031,Q7L7X3,P49327,O95067,O95684,Q9ULX6,O43823,Q13432,Q8IXB1,Q96HY6,P04792,Q9BZF1,P51116,Q06124,Q96S97,P42858,Q96JB5,P51114,P35080,Q9H7B4,Q02750,Q15363,Q92769,Q13217,P31751,Q53EL6 27 +Regulation of metal ion transport 0.4099851095047047 0.316707422042377 0.7514656165240661 1.0 0.9687299302278612 50 Q13555,P62942,P21796,P42858,O14936,O76024,O43865,Q4KMQ2,Q96PU5,Q96GC9,P30536 11 +Regulation of extent of cell growth 0.4251460445074255 0.31645620187426 0.7516562640561779 1.0 0.9687299302278612 21 Q9NQC3 1 +Mesodermal cell differentiation 0.3879003558718818 0.3152259069370325 0.7525901366415959 1.0 0.9689483331771216 2 P52926 1 +Negative regulation of response to biotic stimulus 0.4247718570179031 0.3148658205297333 0.7528635338510155 1.0 0.9691034357127534 21 Q8IXJ6,Q07021,P04439,O43657,Q9Y3Z3,Q96J02,P01889 7 +Extrinsic apoptotic signaling pathway 0.4291437778725245 0.3145577483445054 0.7530974636376695 1.0 0.9692076821835728 32 Q9NR28,P30154,Q07820,P61289,P42858,P09601,P49327 7 +Regulation of protein polyubiquitination 0.4000968292101254 0.3094414988757638 0.7569857067956631 1.0 0.9709700188878144 7 Q96FW1,Q9Y263 2 +Response to amine 0.3947975274131963 0.3088430485286209 0.7574409208332193 1.0 0.9709700188878144 5 Q92769 1 +Male gamete generation 0.3631540382678705 0.3085324132639805 0.7576772401735936 1.0 0.9709700188878144 66 Q9BTX1,Q99417,Q8N2A8,Q9BPZ3,O95470,Q08J23,Q9BW83,O75718,P46379 9 +Water homeostasis 0.4043641735595111 0.308455965002477 0.757735402539204 1.0 0.9709700188878144 9 O76024 1 +Interleukin 1 production 0.4020747233073546 0.3081847312135228 0.7579417701434048 1.0 0.9709700188878144 8 P49755,P04792,P04083 3 +Cellular response to heat 0.4239814352162406 0.3075920742443119 0.7583927518445404 1.0 0.9709700188878144 22 Q99543 1 +Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery 0.3944502378546285 0.3075718999066972 0.7584081049335099 1.0 0.9709700188878144 5 Q5JVF3,P57740 2 +Primary alcohol metabolic process 0.4152650258810123 0.307113388892177 0.7587570669926553 1.0 0.9709700188878144 15 Q9BY49,P51648,Q8NBN7 3 +Skeletal muscle cell differentiation 0.3990486814121549 0.3055442339009857 0.7599516857898609 1.0 0.9721061430864651 7 Q9BYT8 1 +Cell death in response to oxidative stress 0.42289495310533 0.3029671304828508 0.7619149111217336 1.0 0.9736321635063294 22 Q9NR28,Q99720,P04792 3 +Regulation of stress activated protein kinase signaling cascade 0.4242811305212347 0.3021597943690965 0.7625302519937383 1.0 0.973635745896498 24 Q02750,Q7L7X3,Q96J02,Q53EL6,O75844 5 +Protein kinase b signaling 0.4223258971312669 0.3005516071002529 0.763756438001099 1.0 0.9743118124901704 22 Q07021,Q9NQC3,Q9H000,Q99829,Q86UE4,Q9BZF1 6 +Snorna localization 0.3866144535421902 0.2999433581447613 0.7642203610160219 1.0 0.9744194019634872 3 Q8WWY3,Q9Y2X3 2 +Extrinsic apoptotic signaling pathway via death domain receptors 0.4080773108570392 0.2993614305809842 0.764664287439099 1.0 0.9745932400445636 12 P09601 1 +Positive regulation of immune system process 0.2728972792951575 0.2989444525048253 0.7649824288730642 1.0 0.9748026647433355 102 P04083,Q07021,Q15233,Q9UKG1,O96028,P01889,Q5RKV6,Q9NUQ9,Q5JRA6,O00429,Q5JVF3,Q96PK6,O75179,P30825,Q9NUD5,Q06124,P04439,Q07666,P17931,P05771,Q4KMQ2,Q96FZ2,Q9NR50,P51809,P46379,P09601,Q96J02,P43243,Q01650 29 +Negative regulation of ryanodine sensitive calcium release channel activity 0.388763907490656 0.2972179850470188 0.76630009187804 1.0 0.9749134073943264 4 P62942 1 +Positive regulation of sequestering of calcium ion 0.388763907490656 0.2972179850470188 0.76630009187804 1.0 0.9749134073943264 4 P62942 1 +Negative regulation of calcium ion transport into cytosol 0.388763907490656 0.2972179850470188 0.76630009187804 1.0 0.9749134073943264 4 P62942 1 +Response to epidermal growth factor 0.4072439122928761 0.2961547671736132 0.767111890672779 1.0 0.9749675192926996 12 Q9UQB8 1 +Gmp biosynthetic process 0.4052078371133252 0.2958316573717131 0.7673586454063863 1.0 0.9750846810257214 11 P55263,Q06203 2 +Response to electrical stimulus 0.3939214610100222 0.295631103386007 0.7675118177302034 1.0 0.9750846810257214 6 Q7L576 1 +Terpenoid biosynthetic process 0.3881500030209195 0.2950182797848176 0.7679799156141205 1.0 0.97531548947062 4 P48449,O60678 2 +Regulation of tor signaling 0.4049425322685872 0.294822456399154 0.7681295107863142 1.0 0.97531548947062 11 O75844 1 +Response to interleukin 4 0.3959664917108432 0.2941744159842687 0.7686246292378494 1.0 0.9755205839135292 7 P49327,P11802 2 +Body fluid secretion 0.4043958975039146 0.2927463112794154 0.7697160685129882 1.0 0.9759285166400172 11 P00403,Q13505 2 +Response to vitamin d 0.3891179665812531 0.2882714171241469 0.7731389847284396 1.0 0.9782783476010054 5 Q8TB36 1 +Negative regulation of viral transcription 0.3831049597800131 0.2875058620428917 0.7737250140690821 1.0 0.9782783476010054 3 P19474 1 +Tetrapyrrole biosynthetic process 0.4046554436560715 0.2862594157710265 0.774679439544028 1.0 0.9788920455414766 12 Q7KZN9,O00264,P30536 3 +Acidic amino acid transport 0.3981683519592104 0.2852716533667129 0.7754360282819792 1.0 0.9796527334973888 9 Q9UJS0,Q15041 2 +Negative regulation of gtpase activity 0.3956712292928176 0.284447305892681 0.7760676106038678 1.0 0.9798198638215324 8 Q15363,P36404 2 +Dendritic cell migration 0.3879810527175795 0.2842098474102814 0.7762495693647222 1.0 0.9798198638215324 5 Q4KMQ2 1 +Rhythmic behavior 0.3847713704594421 0.2830109949541713 0.7771684086696564 1.0 0.9801163432360614 4 P54802 1 +Pigment metabolic process 0.4215601570595516 0.2829763246463465 0.777194985760014 1.0 0.9801163432360614 27 Q7KZN9,O00264,P09601,Q06203,P30536,P30519 6 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.380918476326103 0.2798490896759363 0.779593287633866 1.0 0.9817731843672116 3 O95140,Q16543 2 +Negative regulation of rig i signaling pathway 0.3802684813671181 0.2775867321476452 0.7813296182365099 1.0 0.982102092247381 3 Q07021 1 +Positive regulation of oxidative stress induced cell death 0.3860781749231552 0.2774549318614205 0.7814308069814149 1.0 0.982102092247381 5 Q96IZ0,Q07820 2 +Regulation of membrane depolarization 0.3913178583822233 0.2772876631516864 0.7815592316874771 1.0 0.982102092247381 7 P30536 1 +Negative regulation of peptide secretion 0.3907737780524194 0.2753322213616368 0.7830610116639465 1.0 0.9826570366509424 7 Q06124 1 +Negative regulation of hormone secretion 0.3907737780524194 0.2753322213616368 0.7830610116639465 1.0 0.9826570366509424 7 Q06124 1 +Positive regulation of hydrolase activity 0.2821857894003599 0.2739982650103026 0.7840859549780188 1.0 0.9828339634152232 83 Q9NR28,Q66K14,Q9BXK5,Q9NZJ7,Q8IZ81,P61289,Q15042,Q96A26,Q9Y263,P49327,O95831,Q96HY6,Q14155,P31751 14 +Regulation of stress granule assembly 0.3791384834460716 0.2736689286400872 0.7843390578093601 1.0 0.9828339634152232 3 Q13131,Q9UN86 2 +Myeloid cell activation involved in immune response 0.392531543623335 0.2730283765244511 0.7848314026535217 1.0 0.9828339634152232 8 P09601 1 +Positive regulation of oxidoreductase activity 0.3899944065233193 0.2725389183740521 0.7852076708368527 1.0 0.9828339634152232 7 P16435,P00374 2 +Tubulin complex assembly 0.3846703007882546 0.2724922533785046 0.7852435469104111 1.0 0.9828339634152232 5 P61758 1 +Protein o linked mannosylation 0.3784264862940578 0.2712103680631482 0.7862292391663726 1.0 0.9830894397265176 3 O60762,O43505 2 +Protein mannosylation 0.3784264862940578 0.2712103680631482 0.7862292391663726 1.0 0.9830894397265176 3 O60762,O43505 2 +Negative regulation of extrinsic apoptotic signaling pathway 0.4119149539851544 0.2709673437281256 0.7864161488721866 1.0 0.9830894397265176 19 P42858,P09601,Q07820 3 +Cellular response to inorganic substance 0.4192717709443265 0.2684110135079814 0.7883829629035204 1.0 0.9840053290850732 31 P09601,Q14168,O95831,Q99829,P35611,P30536 6 +Positive regulation of epithelial cell migration 0.4189367640550648 0.2683269977408711 0.7884476267443168 1.0 0.9840053290850732 29 Q9NQC3,P04083,P09601 3 +Positive regulation of glial cell differentiation 0.3834031647878175 0.2680514452822894 0.7886597195492269 1.0 0.9840053290850732 5 Q92769 1 +Transposition 0.3743772241992886 0.2678443012920355 0.788819168652702 1.0 0.9840053290850732 2 Q9HCE1 1 +Regulation of transposition 0.3743772241992886 0.2678443012920355 0.788819168652702 1.0 0.9840053290850732 2 Q9HCE1 1 +Dendritic transport 0.3828992881632422 0.266292396098616 0.7900140287867621 1.0 0.9849142042930772 5 P33176 1 +Negative regulation of calcium mediated signaling 0.3736654804270539 0.2654266682811031 0.7906807943692384 1.0 0.9851640176794856 2 P42345 1 +Negative regulation of calcineurin mediated signaling 0.3736654804270539 0.2654266682811031 0.7906807943692384 1.0 0.9851640176794856 2 P42345 1 +Negative regulation of dna binding transcription factor activity 0.4146321251255317 0.264539160003628 0.791364493868473 1.0 0.9858220557587012 23 Q92769,P09601,Q96JB5,O76024,Q96J02 5 +Response to calcium ion 0.4114169210796546 0.2640477205344491 0.7917431475065111 1.0 0.9859732423648144 20 Q14103,O43865,Q99829,P35611,Q9UJS0 5 +Regulation of protein export from nucleus 0.3997405543436866 0.2605323618580672 0.7944531558040762 1.0 0.9878570384467246 13 Q06124 1 +Antiviral innate immune response 0.3808336302101819 0.259122164258312 0.7955409840818146 1.0 0.9886925311093272 5 P35232,Q9H078,Q9NVI7,Q99623 4 +Mitotic chromosome condensation 0.3948277355866889 0.257126926716308 0.7970807916670535 1.0 0.9898297034673952 11 Q9ULX6 1 +Filopodium assembly 0.3900864287697214 0.2558857750825218 0.7980390388820191 1.0 0.9907745133245583 9 P51114 1 +Regulation of protein deubiquitination 0.3788950486607684 0.2524536996510523 0.8006903975693818 1.0 0.9919688935664376 5 Q96J02 1 +Positive regulation of necrotic cell death 0.384309644927494 0.2524465682686891 0.8006959091321544 1.0 0.9919688935664376 7 P30536 1 +Trna aminoacylation for mitochondrial protein translation 0.3867124848481928 0.2522622211342973 0.8008383871683598 1.0 0.9919688935664376 8 Q5JTZ9 1 +Lymphocyte mediated immunity 0.4154916374780832 0.2513445194369506 0.8015477580785164 1.0 0.9924595824430557 31 P07437,Q9NUQ9,P13051,Q07021,P04439,O96028,Q9UQ84,P33176,P68371,Q96FZ2,P01889,P51809 12 +Interstrand cross link repair 0.3753561253561263 0.2504623736378523 0.802229799024865 1.0 0.9928287888825535 4 P55072,Q92889,Q16658 3 +Development of primary female sexual characteristics 0.3905909779877082 0.2496120470166755 0.8028873812751514 1.0 0.9928287888825535 10 O95470 1 +Immune response 0.2717631949286786 0.2490957470312176 0.8032867191719606 1.0 0.9928287888825535 199 Q6P179,Q07021,P04083,P18031,Q9NQC3,Q15233,Q9UKG1,O60506,P62942,O96028,P61160,P49327,P08670,P01889,Q9Y487,P10321,Q9NUQ9,O43823,O43657,Q9NPR9,P68371,O75179,Q96PK6,Q9NZ08,Q9NUD5,P07437,P13051,Q06124,P04439,Q9Y3Z3,Q07666,Q96FZ2,P51812,P51809,P46379,Q9NVI7,P09601,Q9UQ84,Q9H000,Q96J02,Q96FW1,Q01650 42 +Regulation of dendrite morphogenesis 0.3966501173707353 0.2490605724614356 0.8033139271993566 1.0 0.9928287888825535 13 Q9UQB8,Q96PU5,Q9UJX6 3 +Urogenital system development 0.413022432786997 0.2481998370256236 0.8039797924413834 1.0 0.9929487321576782 38 P04083,Q9NZJ7,O95470,O76024,O75844,P46379 6 +Regulation of protein kinase activity 0.2637655965922766 0.247523280886716 0.8045032763971136 1.0 0.99301465962768 87 O95684,P42858,Q13432,Q7L7X3,Q96JB5,Q9H7B4,O95067,P04792,Q53EL6 9 +Fibroblast migration 0.3978687038370785 0.2466266854467924 0.8051971503625359 1.0 0.993524376532445 14 O95470 1 +Alcohol metabolic process 0.3232615070259967 0.2465845109349286 0.8052297929415555 1.0 0.993524376532445 74 Q9BY49,Q16850,P51648,O15269,O75874,P53396,Q8NBN7,Q15800,P16435,Q9BQE5,P48735,O76054,P48449,P30837,P37268,Q15392,Q14534 17 +Regulation of calcineurin mediated signaling 0.3739316239316239 0.2456587553903041 0.8059464023211163 1.0 0.9937077660186784 4 Q8IWX8,P42345,P26599 3 +Stress activated protein kinase signaling cascade 0.4139418648833989 0.245158051802316 0.8063340551935552 1.0 0.9937287721080248 30 Q02750,Q9P035,Q7L7X3,Q96J02,Q53EL6,O75844 6 +Negative regulation of mrna catabolic process 0.4121414090344207 0.2422279087356964 0.808603570816087 1.0 0.9953360596540642 27 Q14011,O60506,P35637,P16989,Q14103,Q99729,Q92804,Q9H074,P67809 9 +Regulation of antigen receptor mediated signaling pathway 0.378728514131212 0.242051835033995 0.8087399986048251 1.0 0.9953360596540642 6 P17931,P05771 2 +Embryo development ending in birth or egg hatching 0.2691709386281239 0.2399191402972494 0.8103929423411484 1.0 0.9957125766950008 110 Q96AY3,Q02750,Q15363,P53992,Q15293,O43175,P67809,Q9NQC3,O43772,Q08J23,O43819,P23786,Q4VCS5,O95067,O60313,Q8TCT9 16 +Defense response to symbiont 0.381239970137907 0.2393264708740252 0.8108524409285511 1.0 0.9957125766950008 57 Q9NVI7,P15260,O43657,Q9Y3Z3,Q9NQT4,Q13217,O75179,Q96J02,Q9NUD5,O75844 10 +Response to axon injury 0.3939670678196785 0.2392245700798306 0.8109314515264161 1.0 0.9957125766950008 13 Q96G23,P30536 2 +Negative regulation of b cell activation 0.3688145247419053 0.238796556015376 0.811263340890096 1.0 0.9959271195700384 3 Q96IZ0,Q96FV9 2 +Negative regulation of signaling 0.2695858223766402 0.2379039940976335 0.811955557603401 1.0 0.9960051042455966 177 P50402,Q07021,P18031,O14964,Q15233,P61289,P62942,O76024,P45880,Q9NUQ9,O43657,P16989,Q9NPR9,Q96K76,Q9P0J0,Q96HY6,Q9Y5X3,P04792,O60313,Q8N5M9,P30086,Q06124,Q9Y3Z3,Q96S97,P42858,Q96JB5,Q99829,Q92896,Q07820,O95881,Q9UJX6,P09601,Q9H000,Q96J02,Q53EL6 35 +Positive regulation of ubiquitin dependent protein catabolic process 0.4088388221795963 0.2371022020927536 0.8125775040497853 1.0 0.9962708330091268 24 Q8IXJ6,O95376,Q96JB5,Q9H000,Q96HY6,O43765,O75832,Q9Y5A7 8 +Aminoacyl trna metabolism involved in translational fidelity 0.3847142691015993 0.2369160767503564 0.8127218975640693 1.0 0.9962708330091268 9 Q5JTZ9,Q9BW92 2 +Positive regulation of glycoprotein metabolic process 0.3740648379052298 0.236099126786404 0.8133557515029666 1.0 0.9962899778591828 5 Q96IZ0,P62820,P35222,Q92542 4 +Response to steroid hormone 0.3634397701396261 0.2357867521610483 0.8135981486047985 1.0 0.9962899778591828 63 P04083,O75874,Q969T9,O15118,O95831,Q96HY6,O15173,P40818,Q99829,Q9H7B4,P16435,P30536,Q86X55 13 +Regulation of protein acetylation 0.4064559771268552 0.2351861439138267 0.8140642599699781 1.0 0.9962899778591828 22 Q03164,Q96ST2,Q01105,Q969T9,Q7L7X3,O75844 6 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.3600890537949471 0.2350065570550411 0.8142036439377534 1.0 0.9962899778591828 64 P11802,Q8IXJ6,Q06124,Q92572,Q9NQC3,O14964,Q9UQB8,Q9UKG1,P18031,O95470,P31751,Q7L576,P43490,Q9Y5X3,Q14155,P04792,Q9BZF1 17 +Coronary vasculature development 0.3707264957264952 0.2349705087529322 0.8142316230602349 1.0 0.9962899778591828 4 Q9BYW2,Q13308,Q15750 3 +Negative regulation of lymphocyte activation 0.3978238074208718 0.233436628121639 0.8154223735637554 1.0 0.9968778604075488 16 P17931,P04083,Q96J02,Q92990 4 +Erythrocyte maturation 0.3670345318618765 0.2329570500509369 0.81579475733044 1.0 0.9970475173004818 3 P18074,P11413 2 +Peroxisome fission 0.369968877847414 0.2324685962570419 0.8161740757039908 1.0 0.9971264927195276 4 P40855 1 +Myotube differentiation 0.3957004385671622 0.2319367701419758 0.816587124682391 1.0 0.9972466003299888 15 Q9H7B4 1 +Positive regulation of wnt signaling pathway 0.3997256252687442 0.2287505311116439 0.8190628177446841 1.0 0.9977909387783744 18 Q96K76,Q7Z4L5 2 +Glycerolipid metabolic process 0.3907393058534723 0.2275197022849664 0.8200196507097386 1.0 0.9983601395864772 52 Q92643,Q9Y217,Q9NPH0,Q10713,O15228,Q8N2K0,Q8NCC3,Q8NF37,P42356,Q9BZF1,O43292,Q8WTV0,Q06124,Q96N66,Q9NTJ5,O96017,Q92604,P35790,Q53H12,Q9Y6K0,Q99943 21 +Glutamine metabolic process 0.39057634724182 0.2269622756880878 0.8204530763427742 1.0 0.9986959555866616 13 Q9NQR4,O43175 2 +Response to hormone 0.2663573424330747 0.2250090163422353 0.8219722600821666 1.0 0.9999977961742776 155 P04083,P18031,Q9UQB8,P42785,Q9UKG1,O60343,O15118,P21266,O43865,P05023,Q15392,P20020,P30536,O43823,Q6RW13,Q96PK6,O95831,Q96HY6,O15173,P40818,Q9Y5X3,Q9BZF1,P11802,Q06124,O75874,P35613,P43490,Q99829,Q9H7B4,P09960,Q969T9,P09601,Q7L576,Q86X55,P31751,P16435 36 +Regulation of lymphocyte differentiation 0.3935887438964652 0.2241857628348428 0.8226127611627987 1.0 1.0 15 O96005 1 +Apoptotic mitochondrial changes 0.408170041368219 0.2232695502293724 0.8233257245165035 1.0 1.0 28 P12235,Q9H3K2,O00429,Q96A26,Q3ZCQ8,P52789,P45880,O60313 8 +Positive regulation of erk1 and erk2 cascade 0.3872070417656261 0.2222397394627172 0.8241272599115739 1.0 1.0 12 Q06124 1 +Muscle cell development 0.4056500467390578 0.2207513244332956 0.8252860659981516 1.0 1.0 25 O75844,Q9H7B4 2 +Blood vessel endothelial cell migration 0.401574461776506 0.2204122993246355 0.8255500674615786 1.0 1.0 21 P04083,Q5JRA6,P42785,P09601,Q4VCS5,P06576,P04792 7 +Regulation of t cell activation 0.4083191034852468 0.2196372997051815 0.8261536396838047 1.0 1.0 31 P04083,O96005,Q06124,Q96J02,P30825 5 +Positive regulation of endothelial cell migration 0.3984419528585335 0.2184075301363674 0.8271115989588091 1.0 1.0 19 Q8WTV0,P04083,P09601,P12429,P06576,P04792 6 +Regulation of meiotic nuclear division 0.3620505517977979 0.2168870180742483 0.8282963948887341 1.0 1.0 3 Q15645,Q8IXJ6 2 +Regulation of alpha beta t cell activation 0.3810781678429738 0.2162812408508581 0.8287685306577899 1.0 1.0 10 P04083,Q96J02 2 +Cellular modified amino acid metabolic process 0.3987201086592123 0.2157290335938821 0.8291989685166148 1.0 1.0 46 P23786,Q9UHG3,O60725 3 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.3643416931074478 0.2141853249004476 0.8304025395778067 1.0 1.0 4 Q07820 1 +Glycoside catabolic process 0.3700151680928991 0.2129794215454537 0.8313430136795825 1.0 1.0 6 Q9NUJ1 1 +T cell mediated immunity 0.3772110690118044 0.2112126403250776 0.8327213476906099 1.0 1.0 9 Q9NUQ9,P01889 2 +Steroid metabolic process 0.3655136506298107 0.2085160158323654 0.8348260786371573 1.0 1.0 61 Q9BZF3,Q16850,P53396,O95470,Q15800,O15118,P16435,Q9BQE5,O76054,P48449,P38435,P37268,Q15392,Q14534,P30536 15 +Glucose import 0.383224003530573 0.2083211097337492 0.834978250018453 1.0 1.0 12 P31751,Q9BZF1,Q06124,P52789 4 +Positive regulation of muscle cell apoptotic process 0.3736201426031778 0.2075304509702824 0.8355956138528886 1.0 1.0 8 O95140,Q53EL6 2 +Regulation of meiotic cell cycle 0.3621794871794859 0.2073029828177487 0.8357732447947894 1.0 1.0 4 Q15645,Q8IXJ6,Q9H6S0 3 +Regulation of adaptive immune response 0.3950693478373344 0.2057271128200488 0.8370040785814581 1.0 1.0 19 Q9NUQ9,P04083,P04439,O96028,Q96FZ2,P01889 6 +Sphingolipid metabolic process 0.4011234357600933 0.2025318159033913 0.8395009882527018 1.0 1.0 25 O15269,Q9P035,Q9NZJ7,O95470,Q06136,Q9NZ01,Q96G23 7 +Dsrna processing 0.3871358459316476 0.2009704744709358 0.8407216609914729 1.0 1.0 15 Q02750,Q8IWR0,O75844 3 +Oxaloacetate metabolic process 0.3681848399759135 0.198299978933529 0.8428103681704031 1.0 1.0 7 Q9NQR4 1 +Actin cytoskeleton reorganization 0.3929422755244215 0.1978325876778902 0.8431760487524591 1.0 1.0 19 P04083 1 +Histone h4 deacetylation 0.3621833275697406 0.1975179264867735 0.8434222544526024 1.0 1.0 5 Q92769 1 +Monocyte chemotaxis 0.3651004322659603 0.1971479233518578 0.8437117818642172 1.0 1.0 6 P04083 1 +Tyrosine phosphorylation of stat protein 0.3619350530351962 0.1967376069725052 0.8440328790810063 1.0 1.0 5 Q9UIV1,Q92769 2 +Hepatocyte growth factor receptor signaling pathway 0.3615847611585434 0.1956384940629364 0.8448931285358525 1.0 1.0 5 P18031,Q8IXJ6 2 +Unsaturated fatty acid metabolic process 0.3922427810909145 0.1952540997583338 0.8451940285030441 1.0 1.0 19 P04083,P07099,Q8N8N7,Q9H7Z7,Q9Y263,Q8N4Q0 6 +Positive regulation of peptidase activity 0.4028792488799912 0.1949481144683726 0.8454335668343806 1.0 1.0 34 Q9NR28,Q9BXK5,Q9NZJ7,P61289,Q96A26,P49327,O95831,Q96HY6 8 +Cellular response to steroid hormone stimulus 0.3932622043996713 0.1942654358613483 0.8459680482276015 1.0 1.0 47 P04083,Q969T9,O15118,O95831,Q96HY6,O15173,P40818,Q9H7B4,Q86X55 9 +Glucan biosynthetic process 0.371963856769203 0.1938075080331603 0.8463266079206717 1.0 1.0 9 P31751,P46976 2 +Purine containing compound salvage 0.3690829615071765 0.1927054879996522 0.8471896252147795 1.0 1.0 8 Q13126 1 +Dna double strand break processing 0.3542185831256706 0.1924937363125236 0.847355473867405 1.0 1.0 3 P49959,Q9H4L7 2 +Regulation of membrane permeability 0.3865334631984505 0.1923629319084354 0.8474579261775714 1.0 1.0 16 P45880,P12235 2 +Positive regulation of adaptive immune response 0.3845354343680017 0.1918205926595158 0.8478827398857507 1.0 1.0 15 Q9NUQ9,P04439,O96028,Q96FZ2,P01889 5 +Carbohydrate transmembrane transport 0.3804189690807715 0.1913951270966966 0.8482160375126917 1.0 1.0 13 Q06124,Q9UKG1,P52789,P31751,Q9BZF1 5 +3 utr mediated mrna stabilization 0.3709270291431071 0.1904254292392223 0.8489757725810818 1.0 1.0 9 P98175,P07910,Q92615,Q13151,P16989,Q16539 6 +Histone phosphorylation 0.3876044478040847 0.1899644703905286 0.8493369720506663 1.0 1.0 17 Q9ULX6,O75844 2 +Hepaticobiliary system development 0.3994227987118496 0.1896125462409797 0.8496127550912029 1.0 1.0 27 P04083,P09601,Q15418,Q9UGP8,O75844 5 +Vasculature development 0.2688582853882981 0.1880812056335218 0.8508129939039704 1.0 1.0 84 P04083,P42785,O14964,Q4VCS5,Q96AY3,Q9H6E4,Q15750,Q5JRA6,O75179,P52789,P13489,P06576,Q9NZ08,P04792,Q92990,P35613,P12429,Q8NCW5,Q86UE4,Q02750,Q15363,O95470,P09601,Q53EL6 24 +Positive regulation of transport 0.2645546670959112 0.1873916085814368 0.8513536014506053 1.0 1.0 158 Q03164,P50402,P04083,O14964,Q9UKG1,P33176,O43865,O76024,Q15041,O95071,P20020,P30536,Q9Y282,P61978,P55786,Q15042,Q9P2W9,Q9Y5X3,Q9BZF1,P49755,Q06124,P42858,Q9Y263,O14936,Q07666,Q4KMQ2,Q12907,O75312,P51809,Q9Y4C2,O95376,Q96PU5,Q96GC9,P31751 34 +Transcription coupled nucleotide excision repair 0.3557692307692324 0.1873779393280815 0.8513643181278665 1.0 1.0 4 P19447,P18074,Q93009 3 +Clathrin dependent endocytosis 0.3866744793569457 0.1866535414772484 0.8519322843460126 1.0 1.0 17 Q13432 1 +Membrane repolarization 0.369543661751745 0.1859427401077818 0.8524896648575808 1.0 1.0 9 Q96PU5,O75844 2 +Cellular sodium ion homeostasis 0.3584339618820559 0.1858498891503729 0.8525624801159488 1.0 1.0 5 Q96PU5 1 +Heart morphogenesis 0.394869034045125 0.1857484999989627 0.852641992602587 1.0 1.0 23 Q15363,Q9NQC3,P62942,Q53EL6,O75844 5 +Negative regulation of nuclear division 0.3846284262637137 0.1856532728040072 0.8527166740574432 1.0 1.0 16 Q5JVF3,Q96DY7,O43684,O60216,P49454 5 +Defense response to other organism 0.2640052528893448 0.1847593857947427 0.8534177647834404 1.0 1.0 141 P04083,Q07021,P18031,Q15233,Q9UKG1,O60506,P61160,P08670,P01889,P10321,O43823,O43657,Q8IZ81,P68371,O75179,Q96PK6,Q9NZ08,Q9NUD5,Q8N5M9,P07437,Q06124,P15260,P04439,Q9Y3Z3,Q9NQT4,O75844,P51809,Q9NVI7,Q13217,Q96J02 30 +Histone h3 deacetylation 0.3598297160593093 0.1806409814645969 0.8566493864510274 1.0 1.0 6 Q92769,Q8IXJ6 2 +Protein heterooligomerization 0.3622228206453329 0.1794096430499395 0.8576160601755096 1.0 1.0 7 Q9Y285,Q9NSD9 2 +Detoxification of nitrogen compound 0.3528454195439008 0.1785326142811143 0.8583047101204404 1.0 1.0 4 Q5VT66,P21266 2 +Reactive nitrogen species metabolic process 0.3838537795133347 0.1767076793500731 0.8597380085565927 1.0 1.0 17 O43169,P16435,Q92945 3 +Response to estrogen 0.3691326312231323 0.1766128214215062 0.8598125223689097 1.0 1.0 10 Q969T9,P09601 2 +Spermatid differentiation 0.3853090685491714 0.1758652036186765 0.8603998427227906 1.0 1.0 18 Q8N2A8 1 +Positive regulation of leukocyte cell cell adhesion 0.3867128098767297 0.1751829843481481 0.860935854102681 1.0 1.0 19 P30825,P04083,Q06124 3 +Meiotic cell cycle 0.3849646286446276 0.174554406038101 0.8614297771447219 1.0 1.0 50 Q9BTX1,Q8N2A8,Q08J23,Q9UQ84,O95067,P46379 6 +Thrombin activated receptor signaling pathway 0.3474546101815627 0.1723027439015457 0.8631995272939634 1.0 1.0 3 P16949,Q9NWH9 2 +Metencephalon development 0.3947976618869007 0.1712191608964471 0.8640514417463903 1.0 1.0 27 Q02750,O14949,Q06124,P31939,Q14103,Q7Z4L5,O15228 7 +G protein coupled receptor signaling pathway 0.3970059968993625 0.1711856977425755 0.864077753045227 1.0 1.0 37 P04083,Q8TEY7,O43813,Q9NZJ7,Q6RW13,O43865,Q9BYT8,Q99720 8 +Regulation of fat cell differentiation 0.374103574812985 0.170201910784212 0.8648513490569743 1.0 1.0 13 Q8IXJ6,Q8N4Q0,Q86X55 3 +Regulation of dna binding 0.3907458284231073 0.1701920091161196 0.8648591358444333 1.0 1.0 23 P09601,Q96HY6,O75844 3 +Bone morphogenesis 0.3615277054436483 0.1688319827369588 0.8659288008388493 1.0 1.0 8 O75844 1 +Nuclear membrane organization 0.3889898476016303 0.1681614872995641 0.8664562381159011 1.0 1.0 22 Q86XL3,Q9ULX6 2 +Dendritic spine morphogenesis 0.377191050351942 0.1666391104112961 0.8676540182785626 1.0 1.0 15 Q9UQB8,O60678 2 +Glycerophospholipid metabolic process 0.3875109626453648 0.1643995874597431 0.8694165883148162 1.0 1.0 47 Q92643,Q9Y217,Q9NPH0,Q10713,O15228,Q8N2K0,Q8NCC3,Q8NF37,P42356,Q9BZF1,O43292,Q8WTV0,Q96N66,Q9NTJ5,O96017,Q92604,P35790,Q9Y6K0,Q99943 19 +Lymphocyte activation 0.2579462346167966 0.163553670631041 0.8700825189371546 1.0 1.0 90 Q9NUQ9,P04083,P13051,O96005,Q06124,P04439,P62942,O96028,Q9UQ84,Q96L92,Q96J02,P30825,P51809,P46379 14 +Central nervous system development 0.2634842848361094 0.1622685161161892 0.8710944065643016 1.0 1.0 161 Q9NQC3,Q9UQB8,P62995,Q86XL3,P08670,P20020,O15228,Q9Y6A5,Q15042,P31939,P24539,O95456,Q7Z4L5,P51648,Q06124,P15260,Q96N66,Q14103,Q96JB5,O75312,P51812,P54802,P46379,Q02750,O14949,O43175,O15027,Q9Y320 28 +Negative regulation of proteasomal ubiquitin dependent protein catabolic process 0.3734192554520706 0.1609016981916269 0.8721708247703361 1.0 1.0 14 P46379 1 +Serine family amino acid biosynthetic process 0.3521157656730254 0.1573897717843669 0.8749376739289068 1.0 1.0 6 O43175 1 +Cellular response to calcium ion 0.3629892914572563 0.1572139929345825 0.8750762006687736 1.0 1.0 10 Q99829 1 +Cell morphogenesis involved in neuron differentiation 0.2949401797579901 0.1542854690792269 0.8773846541271242 1.0 1.0 78 Q02750,Q9BVA1,O00264,Q8TEY7,Q06124,Q9NQC3,Q9UQB8,Q9Y4W6,P42892,Q9UJX6,O60678,P61160,Q7L576,P35613,Q96PU5 15 +Axon development 0.3386725757155047 0.1541526695651345 0.8774893602361478 1.0 1.0 67 Q02750,Q9BVA1,O00264,Q8TEY7,Q9Y4W6,Q9NQC3,Q9UQB8,Q06124,P42892,Q7L576,P35613,O75312,Q96G23,P30536 14 +Intermembrane lipid transfer 0.3504469455659823 0.1525049332808994 0.8787886997553342 1.0 1.0 6 P30536 1 +Regulation of peptidyl lysine acetylation 0.3802518237132675 0.152457966611979 0.8788257406116875 1.0 1.0 19 Q03164,Q96ST2,Q01105,Q969T9,O75844 5 +Icosanoid metabolic process 0.378535645644225 0.1523300620540331 0.8789266155004265 1.0 1.0 18 P04083,P07099,Q8N8N7,Q9H7Z7,Q9Y263,Q8N4Q0 6 +Cardiac conduction 0.3723860115446597 0.1507082836388095 0.8802058384778344 1.0 1.0 15 P05023,P16615,P20020,O75844 4 +Lung cell differentiation 0.3429487179487213 0.1497570865977461 0.8809562673820035 1.0 1.0 4 P09960,Q06330,P35222 3 +Protein localization to phagophore assembly site 0.3461094891692752 0.1492958894999321 0.8813201586282939 1.0 1.0 5 O95140,P50851 2 +Cell cycle dna replication 0.3706706927879346 0.1451282594170233 0.8846096066978908 1.0 1.0 15 Q14566,O75844 2 +Lipid homeostasis 0.3811708073447356 0.1449509610683256 0.8847495901618749 1.0 1.0 21 Q9NQC3,Q9Y6C9,O15254,Q5BJF2 4 +Phospholipid biosynthetic process 0.3867632712645443 0.143819667583413 0.8856428718484424 1.0 1.0 44 O15269,Q9Y217,O75874,Q96N66,Q9NPH0,Q9NTJ5,Q8NF37,P35790,Q9Y6K0,O43292,Q99943 11 +Positive regulation of protein targeting to membrane 0.3500156942922878 0.1427592206191671 0.886480344352077 1.0 1.0 7 P31751 1 +Long term synaptic potentiation 0.3553667374028462 0.1420257588848404 0.8870596592775504 1.0 1.0 9 Q9BPZ3 1 +Protein localization to golgi apparatus 0.3489646503138953 0.1397349061252626 0.8888694458658846 1.0 1.0 7 P49755,Q8TD16 2 +Positive regulation of response to oxidative stress 0.331672597864776 0.1379699170808005 0.8902641928245982 1.0 1.0 2 Q96IZ0 1 +Positive regulation of response to reactive oxygen species 0.331672597864776 0.1379699170808005 0.8902641928245982 1.0 1.0 2 Q96IZ0 1 +Muscle cell apoptotic process 0.3638423431122718 0.1373542954352765 0.8907507555217056 1.0 1.0 13 P09601 1 +Regulation of leukocyte differentiation 0.3816972023222161 0.1372075295092082 0.8908667595132056 1.0 1.0 23 P04083,O96005 2 +Positive regulation of lamellipodium organization 0.3631536546517021 0.1352222511721176 0.8924361547764492 1.0 1.0 13 Q14155 1 +Regulation of mitochondrial atp synthesis coupled electron transport 0.3338845574061625 0.1343538606517562 0.8931227646273114 1.0 1.0 3 Q9H3K2 1 +Aspartate family amino acid metabolic process 0.3749013998790643 0.1342522951512986 0.8932030746078299 1.0 1.0 19 Q13126,Q9NQR4,O43175 3 +Adult behavior 0.3712827044772107 0.1342083046252052 0.8932378591833119 1.0 1.0 17 Q92769,Q8N2K0,P04080,O15118,O75844 5 +Regulation of leukocyte proliferation 0.3744284418121015 0.1326703459044616 0.8944540960484038 1.0 1.0 19 P04083,P04439,Q92990,P17931,Q96J02,P30825 6 +Embryonic placenta morphogenesis 0.336452159576263 0.1318729683635449 0.8950847699891595 1.0 1.0 4 Q15363,Q9BYW2 2 +Positive regulation of proteasomal ubiquitin dependent protein catabolic process 0.3784227013286678 0.1304025146942594 0.8962479771418461 1.0 1.0 22 Q8IXJ6,O95376,Q9H000,Q96HY6,O43765,O75832,Q9Y5A7 7 +Amide transport 0.387217374530551 0.130393617070456 0.8962550163175251 1.0 1.0 32 P04083,Q06124,Q9NZJ7,Q9H2D1,P53985 5 +Regulation of intracellular estrogen receptor signaling pathway 0.3538739023680318 0.1297454087568251 0.8967678551901548 1.0 1.0 10 Q969T9,Q96HY6 2 +Divalent inorganic cation homeostasis 0.3779611252283618 0.1295599233678463 0.8969146124388536 1.0 1.0 49 P16615,Q8IYU8,Q8NE01,Q9BPX6,P62942,P42858,Q96A33,Q9HD20,Q8NEW0,O76024,P20020 11 +Neuron death in response to oxidative stress 0.3496960802471662 0.1255274539641451 0.9001059918101944 1.0 1.0 9 O43813,Q07820 2 +Retina development in camera type eye 0.3618162690035114 0.1240649380420305 0.9012638590208948 1.0 1.0 14 Q8NF37,Q8NBN7,P20020 3 +Neural precursor cell proliferation 0.3764570726934728 0.1236265732306132 0.9016109514880366 1.0 1.0 22 O95456 1 +Negative regulation of cellular macromolecule biosynthetic process 0.2569481428327788 0.1227387334205655 0.9023139909083112 1.0 1.0 96 Q969T7,O60506,Q10713,Q9NVN8,P31483,Q14011,Q9Y287,Q99543,Q9BWF3,Q8ND56,P00374,Q5PRF9,P51116,Q9BPZ3,Q9NQT4,Q14103,P51114,Q6PKG0,P67809,P07910,Q14671,Q96B26,Q9Y6M1,Q92889,Q9H074,Q92945 26 +Negative regulation of oxidative phosphorylation 0.3256227758007141 0.1222767851132051 0.9026798168163156 1.0 1.0 2 Q6L8Q7 1 +Double strand break repair via break induced replication 0.3452211126961469 0.1209391814623379 0.903739207605658 1.0 1.0 8 Q9Y248,Q9BRT9,P49736,P33991,Q14566,P33992,P33993 7 +Inner cell mass cell proliferation 0.3322649572649559 0.1207794773814971 0.9038657057660386 1.0 1.0 4 P61201,O75312,Q9BRT9 3 +Attachment of spindle microtubules to kinetochore 0.3703638411885523 0.1192616406239257 0.9050680728945024 1.0 1.0 19 Q8IXJ6,Q9HBM1,Q15005,Q96DB5,Q9BZD4,O43684 6 +Regeneration 0.3820570690986387 0.1167107163915443 0.9070892978645112 1.0 1.0 29 Q02750,P04083,P09601,Q96G23,P30536 5 +Maintenance of protein location in cell 0.3635303421097895 0.1159241096376375 0.9077126877845064 1.0 1.0 16 O43292,P36404,P52789,P30536 4 +Steroid biosynthetic process 0.3808609974547077 0.115864012886468 0.907760317112865 1.0 1.0 44 Q9BZF3,Q16850,P53396,Q15800,P16435,O76054,P48449,Q15392,Q14534,P30536 10 +Acylglycerol homeostasis 0.3227758007117477 0.1151399233203666 0.9083342160816752 1.0 1.0 2 Q8WTV0 1 +Peptidyl lysine deacetylation 0.3227758007117477 0.1151399233203666 0.9083342160816752 1.0 1.0 2 Q8IXJ6 1 +Smooth muscle cell apoptotic process 0.3400718653259945 0.1150056397564411 0.9084406518284964 1.0 1.0 7 O95140,Q53EL6 2 +Regulation of extrinsic apoptotic signaling pathway 0.3795182114268946 0.1135027559250831 0.9096319782904134 1.0 1.0 27 Q07820,P42858,P09601,P30154 4 +Regulation of growth 0.2590272887270405 0.1127825128407062 0.9102029826076032 1.0 1.0 107 Q9NQC3,O14681,O76024,O95067,O95684,Q9Y4W6,P16989,Q96K76,Q9P0J0,P11802,Q5BJF2,Q15418,Q9Y263,P51812,O75844,Q9NVI7,O95470,Q9GZP9,Q7L576,Q96PU5,Q96J02 21 +Cell cycle g2 m phase transition 0.3817964596054067 0.110730971760045 0.9118296850867892 1.0 1.0 41 Q9ULX6,O43823,P11802,Q7L7X3,Q96K76,Q07666,Q96JB5,Q9Y619,O95067,Q9NXR7,P49454,O60216,O96017 13 +Regulation of response to biotic stimulus 0.3474357852424254 0.1101367758937659 0.912300902609376 1.0 1.0 62 Q07021,P18031,Q15233,Q9UKG1,P01889,O43657,Q8IZ81,Q96PK6,O75179,Q9NZ08,Q9NUD5,Q8IXJ6,P04439,Q06124,Q9Y3Z3,P19474,O75844,Q14671,Q96J02 19 +Response to molecule of bacterial origin 0.3827088476298518 0.1101330147607734 0.9123038854140976 1.0 1.0 34 Q8WTV0,Q9NUQ9,O43823,P11802,Q86UE4,Q92769,Q9Y263,P08670,P51812,Q53EL6,P30536 11 +Mrna catabolic process 0.257988753405009 0.1096904959950566 0.9126548380290642 1.0 1.0 103 Q969T7,O60506,P08670,Q92804,Q5RKV6,Q14011,P16989,Q5JVF3,P13489,Q99729,Q6PGP7,Q5PRF9,P51116,Q9NQT4,Q14103,P51114,Q6PKG0,P67809,P07910,P35637,Q96B26,Q9Y4Z0,Q9H074,Q92945 24 +Activation of protein kinase b activity 0.3241766393805641 0.1093832843613674 0.9128984913377718 1.0 1.0 3 Q9BZF1 1 +Cellular response to stress 0.2567084690367466 0.1093620564153541 0.912915327784398 1.0 1.0 411 P04083,Q9P035,Q7L7X3,O76024,P21964,Q9BUN8,P30536,Q9UBU6,Q8TEY7,P61978,P55786,Q96K76,Q99543,O95831,Q96HY6,Q96CS3,P04792,Q9BPX6,O60313,Q9H3N1,Q14566,Q9NR28,Q9NWY4,P16615,P51116,Q06124,Q9Y3Z3,Q4ZIN3,Q96A26,Q9Y4P3,Q15418,Q96A33,Q96JB5,P51114,Q8TCT9,Q99720,P51812,Q9NXR7,O75844,P46379,Q96RU2,Q9BQP7,P67809,Q02750,Q15363,Q8TED1,Q07820,Q13217,O15027,P35637,Q9GZP9,P09601,Q9UQ84,Q15120,P48723,Q96J02,Q9Y679,Q96G23,Q53EL6 59 +Labyrinthine layer development 0.3378988679825974 0.1091999468486516 0.9130439024668492 1.0 1.0 7 Q02750 1 +Negative regulation of defense response 0.3790368191706266 0.1084817044324153 0.9136135926089032 1.0 1.0 28 Q8IXJ6,Q07021,P04439,O43657,Q9Y3Z3,P19474,Q9H000,Q96J02,P01889 9 +Vesicle uncoating 0.3272792022792007 0.108020676019827 0.9139792910828276 1.0 1.0 4 O14976,Q99961,Q9UN37 3 +Protein lipid complex subunit organization 0.3269230769230762 0.1071282321811227 0.9146872500024076 1.0 1.0 4 Q8WTV0,O95573,Q9Y5X1 3 +Cell communication by electrical coupling involved in cardiac conduction 0.3269230769230749 0.1071282321811196 0.91468725000241 1.0 1.0 4 P05023,P05026,P30626 3 +Regulation of response to cytokine stimulus 0.3697227150054617 0.1061641570437153 0.9154521087236052 1.0 1.0 21 Q99829,Q9Y3Z3,Q06124 3 +Protein k48 linked ubiquitination 0.3480472656214978 0.1054344405821757 0.9160310887205844 1.0 1.0 11 Q96PU5,O95376,Q96J02 3 +Cellular metabolic compound salvage 0.3420029722426413 0.1041592679458501 0.9170429575633934 1.0 1.0 9 Q13126 1 +Response to cold 0.3526439948843505 0.1038571417692777 0.9172827190260742 1.0 1.0 13 P00403,Q13217,Q14011 3 +Tumor necrosis factor mediated signaling pathway 0.3446038527626602 0.1034818828500546 0.917580527685149 1.0 1.0 10 Q99829 1 +Skeletal system morphogenesis 0.361056023602502 0.1019429290689603 0.9188019749681268 1.0 1.0 17 O95470,O75844 2 +Positive regulation of transporter activity 0.369746524000957 0.1011011671309511 0.9194701515584158 1.0 1.0 22 Q96GC9,Q03164,P42858 3 +Negative regulation of nf kappab transcription factor activity 0.3516037731621529 0.1008742537156645 0.9196502813941788 1.0 1.0 13 P19474,Q96JB5,Q96J02 3 +Response to fatty acid 0.3405181392986097 0.100171857798182 0.920207887837426 1.0 1.0 9 Q15120,P11802,O15228 3 +Response to retinoic acid 0.339910454384815 0.098552863965993 0.9214932968493073 1.0 1.0 9 Q9P0J0,Q8TB36,Q9NXN4 3 +Regulation of osteoblast differentiation 0.3270395439971416 0.0984544220324753 0.92157146200978 1.0 1.0 5 O00299,P35222,Q96AC1,P17844 4 +Multi multicellular organism process 0.374153513048579 0.0981398436416221 0.9218212495658022 1.0 1.0 26 Q9BQE5,Q9UIQ6 2 +Positive regulation of alpha beta t cell activation 0.3334255647783829 0.0975463388458668 0.922292536585492 1.0 1.0 7 P04083 1 +Negative regulation of helicase activity 0.3230056980056981 0.0974789175183412 0.9223460758708846 1.0 1.0 4 P49736,P04637,P33993 3 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.3230056980056961 0.0974789175183364 0.9223460758708883 1.0 1.0 4 P08069,Q969H8,Q05086 3 +Cellular senescence 0.3683570457874237 0.0965565495007102 0.9230785636722256 1.0 1.0 22 O60313,O75844,P67809 3 +Histone serine phosphorylation 0.3182627269490975 0.0950880910783153 0.9242448571565498 1.0 1.0 3 P52926,Q13131 2 +Mitotic nuclear membrane disassembly 0.3182627269490961 0.0950880910783117 0.9242448571565528 1.0 1.0 3 P53350,P05771 2 +Regulation of muscle adaptation 0.3439495679435939 0.0941353490600734 0.925001640556677 1.0 1.0 11 P16615 1 +Carbohydrate transport 0.3561479465748478 0.0936194345191682 0.9254114709041372 1.0 1.0 16 Q06124,Q9UKG1,L0R6Q1,P52789,P31751,Q9BZF1 6 +Cochlea development 0.3250267154019671 0.0935090897103146 0.9254991287920236 1.0 1.0 5 Q9BW83 1 +Regulation of type i interferon mediated signaling pathway 0.3512803683077498 0.0929424725486602 0.9259492635439815 1.0 1.0 14 Q06124 1 +Regulation of muscle cell differentiation 0.358041683903019 0.0928446986011224 0.9260269399995488 1.0 1.0 17 O75179,Q53EL6,Q9BYT8 3 +Adult locomotory behavior 0.3510761185141343 0.0923617053387469 0.926410664046006 1.0 1.0 14 P04080,Q8N2K0,O75844,O15118 4 +Regulation of calcium ion transmembrane transporter activity 0.3555453377780567 0.0918488460532429 0.9268181345127736 1.0 1.0 16 Q96GC9,P42858 2 +Regulation of neuron projection development 0.3543443095736456 0.0915693950000425 0.9270401685114368 1.0 1.0 58 Q13555,Q02750,Q92769,Q9NQC3,Q9UQB8,Q86VR2,Q8WWV3,Q9UJX6,Q7L576,O14976,Q32P28,Q96PU5,Q86X55,P08670,Q96G23 15 +Epithelial cell proliferation 0.3778545726749917 0.0910626796085135 0.927442786750534 1.0 1.0 34 Q9NQC3,P09601,Q15418 3 +Positive regulation of translational initiation 0.3454638616058975 0.0908977290708284 0.92757385466302 1.0 1.0 12 Q07666,Q13217 2 +Negative regulation of cell morphogenesis involved in differentiation 0.3161267354930637 0.0900977503411549 0.9282095369182912 1.0 1.0 3 O43707,Q9ULV4 2 +Cell communication by electrical coupling 0.3271560940840979 0.0899653993374792 0.928314710623286 1.0 1.0 6 P05026,Q12955,Q16643,P05023,P30626 5 +Regulation of stem cell differentiation 0.3568801990372309 0.0893900710933041 0.9287719140024686 1.0 1.0 17 Q9Y6C9,Q08J23,Q96J02 3 +Regulation of cholesterol metabolic process 0.3333259054861837 0.0892955874597466 0.9288470007595468 1.0 1.0 8 P16435 1 +Positive regulation of intrinsic apoptotic signaling pathway 0.3522681638908676 0.0889562882376122 0.929116649272065 1.0 1.0 15 O60443 1 +Positive regulation of membrane protein ectodomain proteolysis 0.3150587397650454 0.0876371494803994 0.9301650747429028 1.0 1.0 3 O43847,Q9Y5X1 2 +Regulation of lipid biosynthetic process 0.3708592378678617 0.0868281538146619 0.9308081086220424 1.0 1.0 26 P04083,P11802,Q92604,O75874,Q8NF37,O60678,O76054,P05023,P16435,P30536 10 +Inflammasome complex assembly 0.3177835829025442 0.0850966263759745 0.9321845723421178 1.0 1.0 4 Q9H6R0,Q8IXJ6 2 +Deoxyribonucleoside monophosphate catabolic process 0.3099644128113954 0.0850230853899733 0.932243037672824 1.0 1.0 2 O43598 1 +Regulation of axonogenesis 0.3613113191477876 0.0849124423382845 0.93233099995892 1.0 1.0 20 Q9NQC3,Q7L576 2 +Positive regulation of fibroblast proliferation 0.3250178189593657 0.0847662645900955 0.9324472139361416 1.0 1.0 6 Q5TBB1,P11802,Q08211,P14174,Q7Z5K2 5 +Negative regulation of proteasomal protein catabolic process 0.3529543022418703 0.0843231663421957 0.9327994939167136 1.0 1.0 16 P46379 1 +Positive regulation of i kappab kinase nf kappab signaling 0.3716865908059182 0.0823300220787043 0.9343842812853208 1.0 1.0 28 O43657,P09601,O75179,Q8TB61,Q86UE4 5 +Ribonucleoside triphosphate biosynthetic process 0.3652854989363437 0.0816880100389532 0.934894813095748 1.0 1.0 23 P00403,O75964,P24539,P06576,P36542,P56134,Q9UJS0 7 +Circulatory system process 0.3343667794915574 0.0814827783950117 0.9350580201830994 1.0 1.0 65 Q6P179,P16615,Q9NZ08,P42785,Q6RW13,O00429,P42892,Q01650,Q9UIQ6,P09601,Q96PU5,Q9Y5X3,P05023,P30825,P20020,O75844,P53985 17 +Positive regulation of cell aging 0.3232359230220907 0.0805049045038486 0.9358356956680298 1.0 1.0 6 Q96IZ0,P78540,P02545,P04637,O43324 5 +Regulation of membrane protein ectodomain proteolysis 0.3151709401709388 0.0791093669796843 0.9369456330935224 1.0 1.0 4 O43847,Q9Y5X1,Q13464 3 +Response to estradiol 0.3487607851847427 0.0790431376982802 0.9369983114565636 1.0 1.0 15 O95831 1 +Protein localization to cytoplasmic stress granule 0.3223780773374924 0.0784765500047767 0.9374489830701732 1.0 1.0 6 P67809 1 +Secretory granule localization 0.3107867568529754 0.0780259883826676 0.937807380267859 1.0 1.0 3 P33176,Q12756 2 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.334927977745701 0.0779280858340506 0.9378852580747388 1.0 1.0 10 P04792 1 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3749472264151624 0.0777873238335582 0.9379972300097756 1.0 1.0 37 Q4ZIN3,Q96JB5,Q9H000,Q96HY6,O43765,P46379 6 +Positive regulation of protein phosphorylation 0.2817589676815508 0.0767842601648162 0.9387951723369408 1.0 1.0 79 Q02750,Q9Y4R8,Q92769,P51116,Q06124,Q15750,P18031,Q13432,Q7L7X3,P51114,P49327,P35080,Q99627,Q9H7B4,Q96HY6,P31751,Q9BZF1,O96017 18 +Regulation of cell activation 0.3537590607465704 0.0759677648536599 0.9394447439844876 1.0 1.0 57 Q9NUQ9,P04083,P04439,Q06124,Q92990,O96005,O96028,Q15418,P09601,Q5JVF3,Q96FZ2,Q96J02,P30825,Q5RKV6,P51809 15 +Developmental process involved in reproduction 0.2578908836924479 0.0737954396434326 0.9411731557703296 1.0 1.0 128 Q02750,Q9BTX1,Q15363,Q99417,Q8N2A8,P04083,Q06124,Q9NZJ7,Q9BPZ3,O95470,O75874,Q08J23,Q9BW83,O75718,Q15392,P46379 16 +Modification dependent macromolecule catabolic process 0.2588163408435817 0.0735912858208885 0.9413356052455262 1.0 1.0 166 O76024,Q9UHG3,Q9BUN8,Q9UBU6,Q8TEY7,Q96K76,Q96HY6,P40818,Q96CS3,Q9Y263,Q96A33,Q96JB5,O75844,Q96RU2,P46379,Q9UJX4,Q9GZP9,Q15369,Q96PU5,Q9H000,Q96J02 21 +Nuclear envelope organization 0.3715965151403763 0.0732237805021961 0.9416280430763756 1.0 1.0 31 Q86XL3,P50402,Q9ULX6,O75844 4 +Phospholipid catabolic process 0.3295224471620399 0.0720487788560267 0.9425630887745452 1.0 1.0 9 Q8N2K0,Q8NCC3,O75874 3 +Reactive oxygen species biosynthetic process 0.3295220057197493 0.0720476999986634 0.942563947346882 1.0 1.0 9 P00403 1 +Growth 0.2555430399925991 0.0712739097211885 0.9431797594346047 1.0 1.0 146 P04083,Q9NZJ7,Q9NQC3,O14681,O76024,O95067,O95684,Q9Y4W6,P16989,Q96K76,Q9P0J0,P11802,Q06124,Q5BJF2,Q15418,Q9Y263,O75312,Q99829,P51812,O75844,Q15363,Q9NVI7,O95470,O95376,Q9GZP9,Q7L576,Q96PU5,Q96J02,P16435 29 +Lung epithelium development 0.3188958916340579 0.0703980679603536 0.9438768289794636 1.0 1.0 6 Q02750 1 +Embryo development 0.2586075906695075 0.0679651432223742 0.9458133817771994 1.0 1.0 167 Q03164,Q9NQC3,P62995,Q08J23,O43819,P23786,Q4VCS5,O95067,Q96AY3,Q8N2A8,P53992,P16989,O60313,Q9BVA1,Q96S97,Q14168,O75312,Q8TCT9,P54802,P67809,Q02750,Q15363,P46379,Q92769,O43175,P42892,O43772,Q15293 28 +Purine nucleoside monophosphate biosynthetic process 0.3389802557551491 0.0664713520870678 0.9470025649749308 1.0 1.0 13 P55263,Q06203 2 +Alpha ketoglutarate transport 0.3010676156583725 0.0660577680681137 0.9473318335738764 1.0 1.0 2 Q02978 1 +Protein refolding 0.3326172940886679 0.0646980393923173 0.9484144238920912 1.0 1.0 11 P62942,P48723,O60884 3 +Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.3154899587486018 0.0627379735591407 0.9499751584123796 1.0 1.0 6 P04792 1 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.3622193530580486 0.062630116964698 0.9500610466181454 1.0 1.0 25 P49755,Q9Y282,Q96RQ1,P42858,Q12907,Q9P2W9 6 +Leukocyte mediated immunity 0.3695681664740988 0.0621841306047765 0.9504161999734492 1.0 1.0 43 P07437,Q9NUQ9,P13051,Q07021,P04439,O96028,P09601,Q9UQ84,P33176,P68371,Q96FZ2,P01889,Q8N5M9,P51809 14 +Biological process involved in intraspecies interaction between organisms 0.3033107867568576 0.0621003325050393 0.9504829322104592 1.0 1.0 3 Q15334,Q15154 2 +T cell proliferation 0.3568747460673263 0.0606184604811751 0.9516630712219774 1.0 1.0 22 P30825,P04083 2 +Cardiocyte differentiation 0.3466606825668423 0.0602409018393897 0.9519637698920932 1.0 1.0 17 O75844 1 +Regulation of mitochondrial dna replication 0.302242791028842 0.0599183286627231 0.9522206819599266 1.0 1.0 3 Q04837,Q9UJZ1 2 +Regulation of trans synaptic signaling 0.3625510105665646 0.0598398701026541 0.9522831707062698 1.0 1.0 50 Q9BVA1,P16615,Q9UQB8,Q9BPZ3,Q15042,Q9UJX6,Q7L576,P33176,O14936,Q14168,P35080,P05771,Q8IUD2,P40818,Q9UBB6 15 +Tetrahydrofolate biosynthetic process 0.3101515416345645 0.0595205891634888 0.952537466766694 1.0 1.0 5 P31939 1 +Skin development 0.3685491073165308 0.0578626909455007 0.953858001618535 1.0 1.0 33 Q15392,P04083,O75844 3 +Regulation of inflammatory response 0.3642563759634467 0.0571503457434278 0.9544254318233862 1.0 1.0 28 P60900,P04083,Q53EL6,P51809 4 +Regulation of lymphocyte migration 0.304302143513607 0.0556988152810137 0.9555817433080034 1.0 1.0 4 Q5JRA6 1 +Regulation of ion transmembrane transport 0.355487802993865 0.0546748917697142 0.9563974728987996 1.0 1.0 54 P62942,P42858,P21796,Q9Y4C2,O43865,Q4KMQ2,Q96PU5,Q96GC9,O75844 9 +Negative regulation of rna catabolic process 0.3681314045495822 0.054559654478923 0.9564892819164426 1.0 1.0 34 Q14011,Q08J23,O60506,P35637,P16989,Q14103,Q99729,Q92804,Q9H074,P67809 10 +Placenta blood vessel development 0.3113412106166429 0.0537309668146061 0.9571495104801082 1.0 1.0 6 Q02750 1 +Kinetochore assembly 0.3030626780626785 0.053182853353568 0.9575862173210544 1.0 1.0 4 Q15398,P49454,Q7Z3K3 3 +Receptor catabolic process 0.3138714830769881 0.051407733985591 0.9590006220944932 1.0 1.0 7 Q96J02 1 +Granulocyte differentiation 0.3099468617406893 0.0507837733045658 0.959497821218788 1.0 1.0 6 P49327 1 +Odontogenesis 0.3169154161608686 0.0504016576003769 0.959802315493024 1.0 1.0 8 P35613,Q92769 2 +Protein localization to microtubule 0.3122994652406395 0.0480424482260361 0.9616824128531384 1.0 1.0 7 O15344,Q15555,P29372,Q96JM3,Q15691,O60610 6 +Regulation of attachment of spindle microtubules to kinetochore 0.3122994652406336 0.0480424482260235 0.9616824128531484 1.0 1.0 7 Q8IXJ6,Q9P258,P14635,Q9H0H5,P60953,Q96R06 6 +Positive regulation of mrna splicing via spliceosome 0.342108479731026 0.0479896220985707 0.9617245134443702 1.0 1.0 17 Q14011,P38159,Q96E39 3 +Inflammatory response 0.3417902551683668 0.046120165483213 0.9632144733776218 1.0 1.0 60 P04083,P42785,P60900,Q9Y263,P09601,Q9BQE5,Q4KMQ2,Q9H000,Q96J02,Q53EL6,P51809 11 +Dephosphorylation 0.29074718051255 0.0453108827590009 0.9638595131614474 1.0 1.0 76 Q9NQG5,Q13555,Q9Y217,Q969T7,P24666,P18031,Q9NPH0,P30154,P62942,Q06124,Q9NTJ5,P42858,Q96JB5,Q3ZCQ8,Q12972,P05023,Q9H857,Q86XL3 18 +Positive regulation of organelle organization 0.2558035385103307 0.0442707067479768 0.9646886214017304 1.0 1.0 130 P12235,P04083,Q9UQB8,P21796,P36404,P48643,P22626,Q8N2A8,Q15042,Q9P2W9,O15260,Q96A26,P42858,Q14103,P35080,Q9Y6X9,Q9UJX4,Q7L576,P31751 19 +Positive regulation of transmembrane transport 0.3647668186809346 0.042473717956584 0.966121062870164 1.0 1.0 34 Q06124,Q9Y4C2,P42858,Q4KMQ2,Q15041,Q96GC9,P31751,Q9BZF1 8 +Phospholipid metabolic process 0.3387790540772012 0.0424724947931487 0.9661220379334976 1.0 1.0 61 Q92643,Q9Y217,P14324,Q9NPH0,Q10713,O15228,O15269,Q8N2K0,Q8NCC3,Q8NF37,P42356,Q9BZF1,O43292,Q8WTV0,O75874,Q96N66,Q9NTJ5,Q9Y263,O96017,Q92604,P35790,Q9Y6K0,P37268,Q99943 24 +Negative regulation of binding 0.3626164178317089 0.042021887266352 0.9664812500106184 1.0 1.0 31 Q92769,P16615,Q8TEY7,P09601,Q99829,P40855 6 +Negative regulation of innate immune response 0.3257090761438758 0.0409388539579856 0.9673446424188163 1.0 1.0 12 P01889 1 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.3157779915370504 0.0404389461564897 0.967743181087086 1.0 1.0 9 P62942,Q92896 2 +Establishment of endothelial intestinal barrier 0.3043478260869504 0.0393545896824694 0.9686076840227464 1.0 1.0 6 Q9Y624,Q9Y4G8,P62820,Q07157,P49327 5 +Response to nitrogen compound 0.2601909507716994 0.0385466343095312 0.9692518502892566 1.0 1.0 203 P04083,P18031,Q9UQB8,Q9UKG1,O60343,P61160,O15118,O43865,O76024,P08670,Q9BUN8,P20020,O43765,P30536,Q9UBU6,Q6RW13,Q8IXB1,O95831,Q13242,Q96CS3,Q9Y5X3,Q9NUD5,Q9BZF1,Q99729,Q15388,P11802,Q06124,Q4ZIN3,Q96A33,Q14103,P35613,P43490,Q8TCT9,P27824,Q6PKG0,P46379,P49721,Q92769,P23378,P09960,Q9GZP9,Q9Y679,Q7L576,Q86X55,P31751,P16435 46 +Cardiolipin metabolic process 0.3036350677120414 0.0379461984754812 0.9697305784967094 1.0 1.0 6 Q96BW9,Q99623,Q6UWP7,Q9UJZ1,P40939 5 +Meiotic cell cycle process 0.3633971790406089 0.0359387341437418 0.9713312104241814 1.0 1.0 35 O95067,Q9BTX1,Q08J23,P46379 4 +Cellular component morphogenesis 0.2532519699959313 0.0354624646657866 0.9717109763946146 1.0 1.0 110 O00264,Q9NQC3,Q9UQB8,O60678,P61160,Q7L7X3,O15228,Q8TEY7,Q9Y4W6,Q14155,Q9BVA1,Q06124,Q9Y263,P35613,Q99829,Q02750,P42892,Q9UJX6,Q7L576,Q96PU5 20 +Regulation of cell cycle g1 s phase transition 0.3621766372203525 0.0354502819019328 0.9717206907256748 1.0 1.0 33 P04083,P61289,Q9UKG1,Q15058,Q8N6R0,O75179,Q96HY6,Q96DY7,O96017 9 +Plasma membrane organization 0.3562410498410566 0.0354185627693763 0.9717459830483388 1.0 1.0 27 Q9UQB8,P31751,P16615,Q96GC9 4 +Positive regulation of immune effector process 0.3624644825008672 0.0343695716358146 0.972582447447034 1.0 1.0 34 Q9NUQ9,P04083,P04439,O96028,P09601,O75179,P01889,P51809,Q01650 9 +Regulation of cytoplasmic translation 0.3337441868743773 0.0330489414544261 0.9736355592999442 1.0 1.0 16 O60506,Q9H074,P16989,P67809 4 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.3384356279674969 0.0322325732139097 0.9742865799995996 1.0 1.0 18 P46379,Q96RU2 2 +Antigen receptor mediated signaling pathway 0.3405712477860073 0.031721079278859 0.974694484510824 1.0 1.0 19 Q96IZ0,P04439,Q9H4A3,Q07666,P17931,P05771,Q9NR50 7 +Ribonucleoprotein complex disassembly 0.2960456002849996 0.031489778544432 0.9748789436439004 1.0 1.0 5 P33176,P55072,Q14562,Q07866 4 +Regulation of immune system process 0.2566215216862236 0.0309172630681549 0.9753355225666452 1.0 1.0 169 P04083,Q07021,P18031,Q9NQC3,Q15233,Q9UKG1,P62942,O96028,P01889,Q5RKV6,Q9NUQ9,Q5JRA6,O43657,O00429,Q9NPR9,Q5JVF3,Q96PK6,O75179,Q9NZ08,P30825,Q9NUD5,Q06124,P04439,Q92990,Q9Y3Z3,P19474,P17931,Q07666,P05771,Q4KMQ2,Q96FZ2,P51812,Q9NR50,P51809,P46379,O96005,P09601,Q9H000,Q96J02,Q01650 40 +Centromere complex assembly 0.3033868092691574 0.029936114405048 0.9761180036175968 1.0 1.0 7 P49321,Q92674,Q9NRZ9,Q7Z3K3,Q15398,P49454 6 +Trna modification 0.3479096935208772 0.0294051270932918 0.9765414837451633 1.0 1.0 23 O75648,Q08J23,Q5JTZ9 3 +Male sex differentiation 0.3435355746616709 0.028072246855643 0.977604529147824 1.0 1.0 21 Q15392 1 +Negative regulation of reactive oxygen species metabolic process 0.3093875485566364 0.027098679577812 0.9783810279194508 1.0 1.0 9 Q8IXJ6,P52789,Q9NY61 3 +Cell fate specification 0.2935518346989651 0.026959055569773 0.9784923910735464 1.0 1.0 5 P05556,Q06330,Q9UJX6,P35222 4 +Relaxation of muscle 0.28881766381766 0.0265216801795584 0.9788412413973592 1.0 1.0 4 P05023,P05026,P30626 3 +Response to testosterone 0.3125996681870858 0.0264458230069322 0.9789017454420496 1.0 1.0 10 Q13126 1 +Negative regulation of cell differentiation 0.3135942768082179 0.0264217005232211 0.9789209856761992 1.0 1.0 69 P04083,Q06124,Q9NQC3,O75179,Q8N4Q0,Q96G23,Q53EL6,P30536 8 +Regulation of oxidoreductase activity 0.3220143374080559 0.0255942599469769 0.9795809644706056 1.0 1.0 13 Q8TCT9,Q15070 2 +Negative regulation of developmental process 0.245273427527857 0.0233203545327202 0.9813947355590448 1.0 1.0 90 Q92769,P04083,Q06124,P67809,Q9NQC3,P16989,Q9UBS4,O75179,Q4VCS5,Q86X55,Q8NCW5,Q96G23,Q53EL6,Q8N4Q0,P30536 15 +Pinocytosis 0.3036888183389798 0.0231500465267117 0.9815305850116752 1.0 1.0 8 Q9Y5X3 1 +Mitochondrial translation 0.3603959178502467 0.0226825712902007 0.9819034783553796 1.0 1.0 37 Q9Y2R0,Q567V2 2 +Response to zinc ion 0.2908364817587265 0.0221698374874323 0.9823124778729851 1.0 1.0 5 P30536 1 +Protein localization to cell junction 0.3314886664680823 0.0212010179818159 0.9830853022338067 1.0 1.0 17 Q9UQB8,Q14168,P04792,Q5T2T1 4 +Negative regulation of cell cycle 0.2795521036386847 0.0211645942398396 0.9831143576556958 1.0 1.0 78 Q06124,Q08J23,Q7L7X3,Q96K76,Q96JB5,Q8N6R0,Q9Y619,Q96DY7,Q53EL6,Q96RU2 10 +Glycoprotein biosynthetic process 0.3597859826943647 0.0195413371617007 0.9844092610441716 1.0 1.0 41 P04843,Q10472,Q9BT22,Q9Y287,O60502,P46977,Q99805,Q7LGA3 8 +Reproduction 0.2592825773262729 0.0190075298814237 0.9848350985190292 1.0 1.0 209 P04083,Q9NZJ7,Q08J23,Q9UIQ6,Q8NB78,Q9BQE5,O95067,P45880,Q15392,Q8N2A8,Q9BW83,O75718,Q06124,O75874,Q9BPZ3,P46379,Q02750,Q9BTX1,Q15363,Q99417,Q92791,O95470,Q9UQ84,Q96GC9 24 +Polysaccharide biosynthetic process 0.3189624495819737 0.0189045083107916 0.9849172830725884 1.0 1.0 13 P13807,P31751,Q7LGA3,P46976 4 +Xenobiotic catabolic process 0.2889205557534691 0.0188806166148588 0.9849363424861728 1.0 1.0 5 P21266,P78417,P33121,Q08257 4 +Regulation of ryanodine sensitive calcium release channel activity 0.2889205557534665 0.0188806166148541 0.9849363424861766 1.0 1.0 5 P78417,P62942,P17612,P30626 4 +Female sex differentiation 0.3117622981015044 0.0176407562664004 0.9859254429295764 1.0 1.0 11 O95470 1 +Regulation of phosphatase activity 0.3243228068405572 0.0173596763787768 0.9861496778920686 1.0 1.0 15 Q96JB5,P42858 2 +Asymmetric cell division 0.2878517990737418 0.0170780273373202 0.9863743680015432 1.0 1.0 5 Q96N67,Q92974,P61158,P61160 4 +Regulation of dendritic spine development 0.3148018657820173 0.0169401442615809 0.9864843668658028 1.0 1.0 12 Q9UQB8,Q92769 2 +Tricarboxylic acid cycle 0.3392179156450732 0.0166922571832384 0.9866821241745902 1.0 1.0 21 Q13423 1 +Negative regulation of translational initiation 0.2999449623092262 0.0161011222253203 0.9871537182253692 1.0 1.0 8 Q9BPZ3,Q6PKG0 2 +Activation of immune response 0.3582770355815528 0.0156599862213231 0.9875056494494014 1.0 1.0 43 Q96IZ0,Q07021,P04439,P23246,P43243,Q15233,Q9UKG1,Q9H4A3,Q07666,P17931,Q96PK6,P05771,Q9UJZ1,Q9NUD5,Q9NR50,P46379 16 +Regulation of protein targeting to membrane 0.2994088167631854 0.0151155531179407 0.9879399927859144 1.0 1.0 8 P31751 1 +Deoxyribonucleoside monophosphate metabolic process 0.2911617961510984 0.014992486056774 0.9880381749680752 1.0 1.0 6 P04818,P33316,O43598,P00491,P55263 5 +Centromeric sister chromatid cohesion 0.2864267901674332 0.0147103582859105 0.9882632555360872 1.0 1.0 5 P30153,P35222,Q9GZZ1,O60566 4 +Bone development 0.34013551744711 0.0135905387900608 0.9891566527267792 1.0 1.0 22 Q06124,O96028,Q32P28,P16435,O75844 5 +Phosphatidylinositol metabolic process 0.3379953087033162 0.0135488154032376 0.9891899401081016 1.0 1.0 21 Q92643,Q92604,Q9Y217,Q96N66,Q9NTJ5,P42356,O43292,O96017 8 +Response to type i interferon 0.327423130076187 0.0116165153953354 0.9907315701684872 1.0 1.0 17 Q06124 1 +Insulin secretion 0.3392143311894315 0.0111924263914659 0.9910699222304644 1.0 1.0 22 Q13555,P04083,Q06124,P53985 4 +Negative regulation of t cell receptor signaling pathway 0.27859120915713 0.009909411870489 0.99209356265945 1.0 1.0 4 P17931 1 +Negative regulation of antigen receptor mediated signaling pathway 0.27859120915713 0.009909411870489 0.99209356265945 1.0 1.0 4 P17931 1 +Phosphatidylinositol biosynthetic process 0.3292210283792701 0.0096208900891411 0.992323758757643 1.0 1.0 18 Q92643,Q9Y217,Q96N66,Q9NTJ5,P42356,O43292,O96017 7 +Negative regulation of macroautophagy 0.30754217428637 0.0092514909724874 0.9926184834862332 1.0 1.0 11 P09601 1 +Cellular response to oxygen radical 0.2719829120683582 0.0076765625583409 0.9938750494115492 1.0 1.0 3 P00374,P32119 2 +Oocyte maturation 0.2763532763532724 0.006550109723747 0.9947738059506012 1.0 1.0 4 P30153,Q15645,Q8IXJ6 3 +Anatomical structure maturation 0.3476072050751432 0.0055396213367388 0.9955800442688952 1.0 1.0 28 Q08J23,Q8N2A8,Q9NZJ7 3 +Female gamete generation 0.3299167712701998 0.0052324050147216 0.9958251638727154 1.0 1.0 19 Q8N2A8 1 +Nucleus organization 0.3247824348034119 0.005029755194901 0.995986852906436 1.0 1.0 64 Q9NQC3,Q86XL3,O75844,Q9BTX1 4 +Circadian regulation of gene expression 0.329748031433135 0.0048338776211943 0.9961431386973876 1.0 1.0 19 P43490 1 +Poly a plus mrna export from nucleus 0.3044002040438041 0.0032523675047809 0.9974049907568348 1.0 1.0 11 Q5JVF3,Q8N1F7,Q96ST2 3 +Rrna pseudouridine synthesis 0.2731481481481455 0.0019087164934662 0.998477065503639 1.0 1.0 4 Q9UJK0,Q9NX24,Q9NY12 3 +Positive regulation of fat cell differentiation 0.2826086956521682 0.0010820150890265 0.9991366770343668 1.0 1.0 6 Q96A49,Q00839,Q16539,Q86X55,O96017 5 +Response to oxygen radical 0.2720797720797712 0.0004056385920816 0.999676347238988 1.0 1.0 4 P00374,Q9NNW7,P32119 3 +Superoxide anion generation 0.2720797720797692 0.0004056385920788 0.9996763472389902 1.0 1.0 4 P04899,P08754,Q9NY61 3 +Protein localization to microtubule organizing center 0.295041027470577 0.0002795768847352 0.9997769299230184 1.0 1.0 9 Q15154,Q14789,P37198,Q13561,Q9UNZ2,Q15691,Q8WXW3,Q96R06 8 +Activation of gtpase activity 0.319396447401137 8.139464754660827e-05 0.9999350564674624 1.0 1.0 16 Q66K14,P31751,Q9UJX6 3 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..e9fd200cc4879acddc36617a646caafa3b7832c5 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Arterial endothelial cell differentiation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Bile acid signaling pathway", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone mineralization", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in cardiac muscle cell fate commitment", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac cell fate commitment", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell fate commitment", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell myoblast differentiation", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in bone marrow", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cold", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to progesterone stimulus", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal aorta development", "Dorsal aorta morphogenesis", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocardial cushion development", "Endocardial cushion formation", "Endocardial cushion morphogenesis", "Endocardium development", "Endocardium morphogenesis", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial to mesenchymal transition involved in endocardial cushion formation", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart field specification", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus development", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell fate commitment", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 4 production", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Mast cell migration", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell fate commitment", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of behavior", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of ceramide biosynthetic process", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of feeding behavior", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sphingolipid biosynthetic process", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parathyroid gland development", "Paraxial mesoderm development", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion mediated by integrin", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cell adhesion mediated by integrin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell proliferation in bone marrow", "Positive regulation of cell proliferation involved in heart morphogenesis", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 4 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of mast cell chemotaxis", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic development", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Quaternary ammonium group transport", "Quinolinate metabolic process", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of bile acid secretion", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of eating behavior", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of mast cell chemotaxis", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription from rna polymerase ii promoter involved in heart development", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wnt signaling pathway involved in heart development", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Sebaceous gland development", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary heart field specification", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transcription by rna polymerase iii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Thyroid hormone transport", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription factor catabolic process", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Triglyceride biosynthetic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Urogenital system development", "Uronic acid metabolic process", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APOBEC3C", "APOL2", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C19orf70", "C1QBP", "C2orf49", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC6", "CCDC8", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CENPF", "CENPI", "CEP44", "CEP55", "CEPT1", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COG2", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM213A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOLM1", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANBA", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMADHC", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL51", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS27", "MRPS28", "MRPS30", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NF1", "NFATC2IP", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDS5A", "PDS5B", "PDXDC1", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RIPK1", "RMDN1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIP1", "STMN1", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TECR", "TELO2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTC4", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WFS1", "WIZ", "WNK1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCRB1", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AAAS", "AARS2", "AATF", "ABHD10", "ABHD12", "ACAD11", "ACAT2", "ACLY", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACTN4", "ACTR2", "ACTR3", "ADD1", "ADK", "ADPGK", "AFG3L2", "AGK", "AGPAT1", "AGPS", "AGTRAP", "AHCYL1", "AIFM1", "AKAP8", "AKAP8L", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "AMOT", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANKRD17", "ANO6", "ANXA1", "ANXA2", "ANXA3", "AP3M1", "AP3S1", "APLP2", "APOL2", "APOOL", "APPL1", "ARF4", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGEF2", "ARHGEF7", "ARIH2", "ARL2", "ARL6IP1", "ASCC3", "ATAD3A", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATPAF1", "ATPIF1", "AUP1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BCL2L13", "BICD2", "BSG", "BUB1B", "BUB3", "C19orf70", "C1QBP", "CAMK2G", "CANX", "CARM1", "CASK", "CCDC134", "CCDC22", "CCDC47", "CCNB1", "CCNB2", "CCT5", "CDC37", "CDC42", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDS2", "CENPF", "CENPI", "CEP55", "CEPT1", "CERS2", "CHAMP1", "CHCHD3", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CIAPIN1", "CIRBP", "CLCN3", "CLIC1", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "CNNM3", "CNOT7", "COA3", "COMT", "COPG1", "COPS2", "COPS4", "COPS5", "COPS6", "COPS8", "CORO1C", "COX15", "COX2", "COX4I1", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPT2", "CRKL", "CRTAP", "CRYZ", "CSNK2B", "CSTB", "CTNNB1", "CUTA", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DBN1", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DDRGK1", "DDX3X", "DDX5", "DERL1", "DERL2", "DFFA", "DHCR24", "DHFR", "DHRS7", "DHX33", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DLGAP5", "DNAJA2", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNPH1", "DOCK7", "DPH5", "DPM1", "DPP3", "DUT", "DYNLL1", "ECE1", "EEF1E1", "EFL1", "EI24", "EIF2B3", "EIF4A3", "EIF4B", "EIF5", "EIF5A", "ELMOD2", "ELOC", "ELP2", "EMC7", "EMD", "EPHX1", "EPPK1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC2", "ERGIC3", "ERLIN1", "ERO1A", "EXO1", "EXOSC5", "EXOSC6", "EXOSC8", "F11R", "FAF2", "FAM162A", "FAM49B", "FAM8A1", "FAM98B", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FERMT2", "FGFR1OP", "FKBP10", "FKBP1A", "FKBP5", "FLOT2", "FNTB", "FOXRED1", "FSCN1", "FUBP3", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP2", "G6PD", "GAK", "GALNT1", "GAPVD1", "GAR1", "GCAT", "GCDH", "GCN1", "GDAP1", "GDAP2", "GGCX", "GHITM", "GINS2", "GINS4", "GLDC", "GLG1", "GLMN", "GLRX3", "GLRX5", "GNA13", "GNAI2", "GNAI3", "GNL3L", "GNPAT", "GOLGB1", "GPAA1", "GPD2", "GPR108", "GPX8", "GSDME", "GSTM3", "GSTO1", "GUSB", "GYG1", "GYS1", "HACD3", "HACL1", "HADHA", "HAUS5", "HDAC1", "HDAC2", "HEATR3", "HELLS", "HGS", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMCES", "HMGA2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPK", "HNRNPU", "HPF1", "HS2ST1", "HSD17B11", "HSD17B12", "HSD17B4", "HSPA13", "HSPB1", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IKBIP", "ILVBL", "INTS13", "IPO9", "IQSEC1", "IRS4", "ITCH", "ITGB1", "ITM2B", "IWS1", "JAGN1", "KDM1B", "KDSR", "KHDRBS1", "KHSRP", "KIF14", "KIF18A", "KIF1A", "KIF5B", "KLC1", "KMT2A", "KPNA2", "LANCL1", "LARP1", "LARP4", "LARP4B", "LARS", "LCLAT1", "LETM1", "LGALS3", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRBA", "LRRC59", "LRSAM1", "LRWD1", "LSM14A", "LSM4", "LSS", "LTA4H", "MAP2K1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MATR3", "MAU2", "MBOAT7", "MCL1", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "METTL13", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MKRN2", "MMADHC", "MORC2", "MOV10", "MPG", "MPP2", "MPP7", "MPV17L2", "MRE11", "MSMO1", "MSTO1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTMR6", "MTOR", "MTPN", "MTX1", "MTX2", "MYADM", "MYCBP", "MYDGF", "MYH9", "MYL6", "MYL6B", "NAA40", "NAA50", "NAGLU", "NAMPT", "NAP1L1", "NASP", "NAXE", "NCAPH", "NCDN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4L", "NENF", "NFATC2IP", "NHP2", "NIT2", "NLN", "NNT", "NOB1", "NOC2L", "NONO", "NOP58", "NPC1", "NPEPPS", "NRDC", "NSD2", "NSFL1C", "NSUN2", "NT5C3B", "NT5DC2", "NTMT1", "NUB1", "NUCB2", "NUDT12", "NUF2", "NUP107", "NUP160", "NUP37", "NUP62", "NUP85", "NUP93", "NXF1", "OCIAD1", "OPA1", "OSBPL6", "OSBPL8", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HB", "PAIP1", "PAIP2", "PAWR", "PCID2", "PCLAF", "PCM1", "PCYOX1", "PDCD4", "PDCD5", "PDCL3", "PDE12", "PDE6D", "PDK3", "PDLIM5", "PEBP1", "PECR", "PEX14", "PEX19", "PFDN5", "PFDN6", "PFN2", "PGRMC1", "PGRMC2", "PHB", "PHB2", "PHGDH", "PI4KA", "PIBF1", "PIGK", "PIGS", "PITRM1", "PLA2G15", "PLAA", "PLCG1", "PLD6", "PLEC", "PLK1", "PMPCA", "PNP", "POGZ", "POLDIP2", "POR", "PPAT", "PPP1R8", "PPP2R1A", "PPP2R1B", "PRCP", "PRDX2", "PREB", "PRKAA1", "PRKACA", "PRKAR1A", "PRKCB", "PRMT3", "PRMT5", "PRPF31", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSME3", "PSMG1", "PTBP1", "PTGES2", "PTGR2", "PTK7", "PTPN1", "PTPN11", "PTRH2", "PUM1", "QSOX2", "RAB13", "RAB1A", "RAB3GAP1", "RAB3GAP2", "RAB5B", "RAB5C", "RABGGTA", "RACGAP1", "RAD21", "RANBP2", "RAPGEF2", "RBM10", "RBM14", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCC2", "RCN1", "RDH13", "RER1", "RETREG3", "REXO2", "RMDN1", "RNASEH2B", "RNH1", "ROCK1", "RPN1", "RPRD1B", "RPS3", "RPS6KA1", "RPS6KA3", "RTN3", "RTN4", "RTN4IP1", "SACM1L", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SCARB1", "SCCPDH", "SCO1", "SCO2", "SDHB", "SEC11A", "SEC13", "SEC14L2", "SEC16A", "SEC23B", "SEC24C", "SEC63", "SET", "SETD2", "SFPQ", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SHTN1", "SIGMAR1", "SIRT2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A6", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC7A1", "SLC7A5", "SLTM", "SMARCAD1", "SMARCE1", "SMYD3", "SNX27", "SNX5", "SNX9", "SORT1", "SPAG5", "SPC25", "SPCS2", "SPTLC1", "SQLE", "SQSTM1", "SRI", "SRP9", "SRPRB", "SRSF1", "SRSF7", "SRSF9", "SSBP1", "SSR1", "STMN1", "STOML2", "STT3A", "STX18", "STX5", "SUN1", "SURF4", "SYAP1", "SYNCRIP", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAMM41", "TAOK1", "TARDBP", "TARS2", "TBC1D4", "TBC1D9B", "TBCE", "TBL2", "TCAF1", "TECR", "TELO2", "THOC1", "THOP1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TJP1", "TM9SF2", "TM9SF3", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM199", "TMEM201", "TMEM259", "TMEM33", "TMEM97", "TMX1", "TMX2", "TOMM20", "TOMM22", "TOMM5", "TOMM70", "TOR1AIP2", "TP53", "TP53BP2", "TPM1", "TRA2B", "TRAM1", "TRIM21", "TRIP13", "TRMU", "TSPAN6", "TSPO", "TSR3", "TTC19", "TTC21B", "TTC26", "TTC37", "TTLL4", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TXNDC12", "TXNDC9", "TXNRD2", "TYMS", "UBE3A", "UBR5", "UFD1", "UNC119", "UNC119B", "UNG", "UQCR10", "UQCRFS1", "UQCRQ", "USP28", "USP33", "USP47", "USP7", "USP8", "VAMP7", "VBP1", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS4A", "WAPL", "WBP2", "WFS1", "WIZ", "WNK1", "YBX1", "YBX3", "YIF1A", "YIPF5", "YRDC", "YTHDC2", "YWHAB", "ZADH2", "ZC3H7A", "ZCCHC3", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_gocc/advanced/idx2term.json b/msigdb_gocc/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..d3ed58882c460df88ffe0906bed67f39ddabb422 --- /dev/null +++ b/msigdb_gocc/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Nuclear outer membrane endoplasmic reticulum membrane network", "1": "Organelle subcompartment", "2": "Endoplasmic reticulum", "3": "Mitochondrial envelope", "4": "Envelope", "5": "Intrinsic component of organelle membrane", "6": "Organelle inner membrane", "7": "Membrane protein complex", "8": "Mitochondrial protein containing complex", "9": "Inner mitochondrial membrane protein complex"} \ No newline at end of file diff --git a/msigdb_gocc/advanced/plot_0.png b/msigdb_gocc/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..aaf30bebceec9b9cf672c015de4a97e849441949 --- /dev/null +++ b/msigdb_gocc/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d17c1f9f218a5287502543df555abf67125a002ebd926cb1d2f5f4ccbedff8d4 +size 227894 diff --git a/msigdb_gocc/advanced/plot_1.png b/msigdb_gocc/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..18047ecc1fc2c1571aa731a412151529790c1ce2 --- /dev/null +++ b/msigdb_gocc/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c167cb9d0907ea4a40623abdb356a5435d6eeb57ce293b2694aa74a460df461 +size 224616 diff --git a/msigdb_gocc/advanced/plot_2.png b/msigdb_gocc/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..96ed97812ee48331c7d6a6f08ac428ecc26b2630 --- /dev/null +++ b/msigdb_gocc/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41ac2255837a673bd6d4541581e70c9f3d68da021823d066092cac2f09ff8064 +size 225448 diff --git a/msigdb_gocc/advanced/plot_3.png b/msigdb_gocc/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4594028dd57c97eef387eb50ff6642619f499154 --- /dev/null +++ b/msigdb_gocc/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c7fd02e4ab832c29b4676569db03e501a338f6cb17a6a660a1e6e1c9c615372 +size 221316 diff --git a/msigdb_gocc/advanced/plot_4.png b/msigdb_gocc/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..47be0b6f2bb0f7764d974e8e3f4376b4c21a4b55 --- /dev/null +++ b/msigdb_gocc/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90bbcaffe67a7b305fe3ff1a6cdf8aa4b729bdd41fc4817560babf8b88d463d6 +size 224683 diff --git a/msigdb_gocc/advanced/plot_5.png b/msigdb_gocc/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..e8855f0c1cfb454a315f4e306433292fd50a3b63 --- /dev/null +++ b/msigdb_gocc/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79230fdbe27ae5b1a4ec0dcba2c92a476ffff9badcf7d7bfe7c91f2479ac8884 +size 215461 diff --git a/msigdb_gocc/advanced/plot_6.png b/msigdb_gocc/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4727c8ab02e561b02b0e589837cdcf42e5a126d5 --- /dev/null +++ b/msigdb_gocc/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d38a5b21754e5755614e09417b9a0a82dfa6f381499cb9b776325ab03bf55f7 +size 222558 diff --git a/msigdb_gocc/advanced/plot_7.png b/msigdb_gocc/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..8e4634d4268a08f01e1e6b0be2bb5b08a1debfc7 --- /dev/null +++ b/msigdb_gocc/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29f18be9e7edd1385f7d63fee01a746d2a3bdd11d6ecf87714103c1a40180365 +size 220223 diff --git a/msigdb_gocc/advanced/plot_8.png b/msigdb_gocc/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e2dbc7e00e016eb3f2704749574130d485639a10 --- /dev/null +++ b/msigdb_gocc/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d1dba783c3e31afd8ed13e280e38db1dbecd815c0902a86cd0e9bdfe0cb2bbe +size 219602 diff --git a/msigdb_gocc/advanced/plot_9.png b/msigdb_gocc/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c81a2e346467d8511f931f6528153c9a5924b87d --- /dev/null +++ b/msigdb_gocc/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e613fc4f29a0886502124dd876d65d43ad163650eca1b6bed1f451d2f5e9b74 +size 210475 diff --git a/msigdb_gocc/basic/idx2term.json b/msigdb_gocc/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..646e1a053a27df06b417b240770ecf3d3c294494 --- /dev/null +++ b/msigdb_gocc/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Nuclear outer membrane endoplasmic reticulum membrane network", "1": "Organelle subcompartment", "2": "Endoplasmic reticulum", "3": "Mitochondrial envelope", "4": "Envelope", "5": "Intrinsic component of organelle membrane", "6": "Organelle inner membrane", "7": "Membrane protein complex", "8": "Mitochondrial protein containing complex", "9": "Inner mitochondrial membrane protein complex", "10": "Mitochondrion", "11": "Golgi membrane", "12": "Intrinsic component of endoplasmic reticulum membrane", "13": "Outer membrane", "14": "Intrinsic component of golgi membrane", "15": "Proton transporting two sector atpase complex proton transporting domain", "16": "Intrinsic component of mitochondrial inner membrane", "17": "Intrinsic component of mitochondrial membrane", "18": "Respirasome", "19": "Mitochondria associated endoplasmic reticulum membrane", "20": "Organelle membrane contact site", "21": "Respiratory chain complex iv", "22": "Endoplasmic reticulum golgi intermediate compartment membrane", "23": "Proton transporting two sector atpase complex", "24": "Cytochrome complex", "25": "Mib complex", "26": "Nuclear envelope", "27": "Golgi apparatus", "28": "Nuclear membrane", "29": "Oxidoreductase complex", "30": "Transporter complex", "31": "Copii coated er to golgi transport vesicle", "32": "Proton transporting atp synthase complex", "33": "Organelle envelope lumen", "34": "Endoplasmic reticulum golgi intermediate compartment", "35": "Er to golgi transport vesicle membrane", "36": "Endoplasmic reticulum protein containing complex", "37": "Vesicle membrane", "38": "Lipid droplet", "39": "Coated vesicle", "40": "Rough endoplasmic reticulum", "41": "Vacuolar membrane", "42": "Intrinsic component of plasma membrane", "43": "Endoplasmic reticulum exit site", "44": "Microtubule", "45": "Transport vesicle", "46": "Early endosome", "47": "Peptidase complex", "48": "Collagen containing extracellular matrix", "49": "Transport vesicle membrane"} \ No newline at end of file diff --git a/msigdb_gocc/basic/plot_0.png b/msigdb_gocc/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7ebf65f530b8347c9cd87d8ed9501b8c327684fc --- /dev/null +++ b/msigdb_gocc/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b15e13330ae16a004f61949e7c17e7fbebd6ec4ef44a5254f32cd5b9f6b60267 +size 146219 diff --git a/msigdb_gocc/basic/plot_1.png b/msigdb_gocc/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..e90f32854aa7700537de819f4a363997024c6f1a --- /dev/null +++ b/msigdb_gocc/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62ad46344e40ca1cdebad3b670971a93a0c7f3012aca19b6e8bb98985eac77f1 +size 139706 diff --git a/msigdb_gocc/basic/plot_10.png b/msigdb_gocc/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..ecbc1a5a8abad297845a48c435771ab25b44500f --- /dev/null +++ b/msigdb_gocc/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f8629dc0391fec512208abbb330e8bea3cf32d39bdd2b546468f91c62d990cc4 +size 136131 diff --git a/msigdb_gocc/basic/plot_11.png b/msigdb_gocc/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..d21236ee65cb2420d270f442686faaf9439be224 --- /dev/null +++ b/msigdb_gocc/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b194951c0bf691afb899b271aabeca93b5974c7eecaaa7e2b7b4bae842e532f4 +size 140359 diff --git a/msigdb_gocc/basic/plot_12.png b/msigdb_gocc/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..27bc60f192c335b5f93d540f32ac806a97587a79 --- /dev/null +++ b/msigdb_gocc/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f191b534b129e86a4419a916439e70ee5ac4bf0a53824eecbe03e5f5d8e3411 +size 139408 diff --git a/msigdb_gocc/basic/plot_13.png b/msigdb_gocc/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..95808e7a50c821543e97f7fa320f3cd4614e31e9 --- /dev/null +++ b/msigdb_gocc/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:613fdae9038eb41e35f1d4aeb19de7bf24f7e839848e131f68412d3bc8fd2f9b +size 129392 diff --git a/msigdb_gocc/basic/plot_14.png b/msigdb_gocc/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..95c0208bf1e3dea2443febc799e3eedd540f61a0 --- /dev/null +++ b/msigdb_gocc/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:363390974fadcf8b503fe206265fb5a87da051cc3adefaa2d5fcd3718ece44a4 +size 135859 diff --git a/msigdb_gocc/basic/plot_15.png b/msigdb_gocc/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..7b1111247f503efc832a76e9bbd6d65f85d934fd --- /dev/null +++ b/msigdb_gocc/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa68ff85e9d631b74f6de3e2af122286ec69083c85272e83fe89993f4a9701ae +size 132651 diff --git a/msigdb_gocc/basic/plot_16.png b/msigdb_gocc/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..c46f4f2e880c4fb4747468cd6af342dda7aeae2a --- /dev/null +++ b/msigdb_gocc/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6efd95aff4377047b815c6dbb87f1cad311efe25444e570cb7ace10b43a8723 +size 138810 diff --git a/msigdb_gocc/basic/plot_17.png b/msigdb_gocc/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..c533ab5c96346d9d8654c3e8e481d7f34acfc7b9 --- /dev/null +++ b/msigdb_gocc/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6e3786abbc11308c67cdfddccf7259bb8bcd288ae23220240722498b832cc4d +size 138825 diff --git a/msigdb_gocc/basic/plot_18.png b/msigdb_gocc/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..e6d8f01732b71176ccc6d381168abb174dfa1d25 --- /dev/null +++ b/msigdb_gocc/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d55bb7de0f3297a01d2f73ed8132f292e491f460708a15e766ccf6c3d5ec3f1 +size 131735 diff --git a/msigdb_gocc/basic/plot_19.png b/msigdb_gocc/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..d4d42dd823076d93d35df70441d2d93351ef1441 --- /dev/null +++ b/msigdb_gocc/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e3192de1ba3a9eb247027915901d0ec3904dd68b2bf3985ed977a35fdd9411eb +size 139620 diff --git a/msigdb_gocc/basic/plot_2.png b/msigdb_gocc/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ef84f7cb70ddfeb48099f49bbd7290554dbe6549 --- /dev/null +++ b/msigdb_gocc/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:044a972f38b7cc8c9b12b1c9c7d2e7b5b3ac5a70f6dc966b2d142ce1432a4b97 +size 137624 diff --git a/msigdb_gocc/basic/plot_20.png b/msigdb_gocc/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..498d2af3a6d32f6cfa1293053d69a524e64b46aa --- /dev/null +++ b/msigdb_gocc/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:852dfd9c2419e39af73db7965b679b220a6a2fdfbfe5ff79924e4cf6f45ccfd5 +size 138563 diff --git a/msigdb_gocc/basic/plot_21.png b/msigdb_gocc/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..570d5d635c42a89bc635733665af543666335714 --- /dev/null +++ b/msigdb_gocc/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:69a0bf94164f3bc900facd501f483708b1c83debce3dee4c30f066085591b7d4 +size 136964 diff --git a/msigdb_gocc/basic/plot_22.png b/msigdb_gocc/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..01570d5814831b02385182b3b4627ae2a190a1a9 --- /dev/null +++ b/msigdb_gocc/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ec926610c9a595d7141c0c00182c71fe582f76292f63882263a2a1a69cc15864 +size 142645 diff --git a/msigdb_gocc/basic/plot_23.png b/msigdb_gocc/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..e2835924200853f9062731569f8480632e5d2355 --- /dev/null +++ b/msigdb_gocc/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33195c78a2d02c240f88f6b8c52d2c9add2c7710a01d05a6a8241aaa0586f9b1 +size 144148 diff --git a/msigdb_gocc/basic/plot_24.png b/msigdb_gocc/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..387f54f8f3349fb34800fad74de07f7e2d173f9c --- /dev/null +++ b/msigdb_gocc/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6fb2ea07e36f367b3a246e9618be7c815f05cd88ce894978d569e84f6db4cc4b +size 134268 diff --git a/msigdb_gocc/basic/plot_25.png b/msigdb_gocc/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..f7e2239576822b6a011d862289da8aa17fa09a27 --- /dev/null +++ b/msigdb_gocc/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e36dfba64918951f0312ce863668682ba978d1d06ac3bd0f75d086660b3e243a +size 131807 diff --git a/msigdb_gocc/basic/plot_26.png b/msigdb_gocc/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..417b39ab8f6b11a44df12fbf9fcac9705f335914 --- /dev/null +++ b/msigdb_gocc/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42560bb6695ec2d6e80c14f5bba10d63fa5f0ada51b41d7b681fc87ccc759f06 +size 137608 diff --git a/msigdb_gocc/basic/plot_27.png b/msigdb_gocc/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..34c4f221cee63a1d4c6050671d556e6df8af87af --- /dev/null +++ b/msigdb_gocc/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14d4044007052d09ca5b6eced2798c1761af730bb407e29883121a6bb1be185e +size 137985 diff --git a/msigdb_gocc/basic/plot_28.png b/msigdb_gocc/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..82a820fd838cccc0e843d7f9f13216c1d4214cd4 --- /dev/null +++ b/msigdb_gocc/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:85538406d1b261dbe2c647c7ebc985eb0a24d19fd8c2f56f1d2bf6675c23058b +size 141641 diff --git a/msigdb_gocc/basic/plot_29.png b/msigdb_gocc/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..62552d2bd55516d1eb2d9eff9e01a98c441a360e --- /dev/null +++ b/msigdb_gocc/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8e723766736dc806864daaa130761bf8fca5d6848bb99e26a5c01964057809a +size 146488 diff --git a/msigdb_gocc/basic/plot_3.png b/msigdb_gocc/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..abb5deefe7eff8a7f8f199e84dbc312419beff1a --- /dev/null +++ b/msigdb_gocc/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0848c20a4e9a7aa078a9d0b9687f901c3178add5f4a311a4fe42992819b5e17b +size 136014 diff --git a/msigdb_gocc/basic/plot_30.png b/msigdb_gocc/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..3a843dc4ba3d4a1a7f17e5a640dd181748db3300 --- /dev/null +++ b/msigdb_gocc/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5fd8c7fc0739a4ecd8339c6efe97d9ca08eae8e505c0913a29083c2cee0cb52e +size 135653 diff --git a/msigdb_gocc/basic/plot_31.png b/msigdb_gocc/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..cbb640850f2aa9c59a591ea0de7090547957d433 --- /dev/null +++ b/msigdb_gocc/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fd665219f70945b893fdd2e2c541f8be6b0c789e158083c84fd3b93f00009a4 +size 143170 diff --git a/msigdb_gocc/basic/plot_32.png b/msigdb_gocc/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..1454d8814fbd5e459947b4b37f7ac85848388eac --- /dev/null +++ b/msigdb_gocc/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba1f297b4e143eff59f77716ca0478d6f845726bafbfd0d792e530e73e46fdf0 +size 144783 diff --git a/msigdb_gocc/basic/plot_33.png b/msigdb_gocc/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..290e06a6470bfe2e507fc0ccf2946b6198ff3c34 --- /dev/null +++ b/msigdb_gocc/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fdea6b8456fc440abfd2fbbbbae46fd1204e26178a54e4127a43fd033673868 +size 138191 diff --git a/msigdb_gocc/basic/plot_34.png b/msigdb_gocc/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..714edb536ad63fd561fa574111b2c55366ecc631 --- /dev/null +++ b/msigdb_gocc/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3db0ad49428723fa8fb23fa337844046f12f5ce572f60bcedf17da5c4beda7d7 +size 144615 diff --git a/msigdb_gocc/basic/plot_35.png b/msigdb_gocc/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..f1b0f915297915c2ee5878482def824d5bdbc45f --- /dev/null +++ b/msigdb_gocc/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2347f93851ae8822d9125aca3ba7612a896fbc2550930ff8f22238b9c21d056 +size 145270 diff --git a/msigdb_gocc/basic/plot_36.png b/msigdb_gocc/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..13cee3c3ac7d08498200f4296db7959cf0a6a5f4 --- /dev/null +++ b/msigdb_gocc/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4bdf8e9d78e015dfbb34477fd543b8f38b33c20b319bfcaf989ed99f83ed092b +size 145048 diff --git a/msigdb_gocc/basic/plot_37.png b/msigdb_gocc/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..7c9869fccb843c8f50409f7f8ea2f850a4f5aeeb --- /dev/null +++ b/msigdb_gocc/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cf0e556a60b7c51bf1238952fe06a9c5d78ede11a5333c2104d49c404b2f3b19 +size 143435 diff --git a/msigdb_gocc/basic/plot_38.png b/msigdb_gocc/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..1dcc94cc3162d34933088711c4a52c96c4594775 --- /dev/null +++ b/msigdb_gocc/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe5951b266f47222db1d9507e8f29c901cc915f50bdabc3b67598ede44ecc642 +size 134723 diff --git a/msigdb_gocc/basic/plot_39.png b/msigdb_gocc/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..fe122716758bdaa0f2dccb09f6827ca624e9f494 --- /dev/null +++ b/msigdb_gocc/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9563982abb5ef4f0f092fb3d2a279186298228764af138889c2e68e77ab702be +size 144205 diff --git a/msigdb_gocc/basic/plot_4.png b/msigdb_gocc/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..76daed41f0685ab94a7bae2ca1cad6b2d33f1b5d --- /dev/null +++ b/msigdb_gocc/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0d0e038c89bf531cc2c38b797c4049ee59ae5a155167270c3e0c3ee1d478aa3 +size 136604 diff --git a/msigdb_gocc/basic/plot_40.png b/msigdb_gocc/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..76d5ea137cd4768a3bd7d885a5ad1a17240019f1 --- /dev/null +++ b/msigdb_gocc/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52247b402b70c1d66123c6c14684490134c729d3d1615ed8fdd6112d19439a2d +size 139948 diff --git a/msigdb_gocc/basic/plot_41.png b/msigdb_gocc/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..aa3ab796a420df47a67abf46e0ca666a74cf3d0b --- /dev/null +++ b/msigdb_gocc/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72e12aa5023ce7ce720e7cd14ff0c3b9457012abac9e3e6853499fcc0714a51a +size 143054 diff --git a/msigdb_gocc/basic/plot_42.png b/msigdb_gocc/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..a1c7156870755bca765a6d1f9cf5634f19cf14c5 --- /dev/null +++ b/msigdb_gocc/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3d3c1ba43221bff2c44a7279675f4451edc33ed419b7668dae4cc76afba6ea2 +size 145733 diff --git a/msigdb_gocc/basic/plot_43.png b/msigdb_gocc/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..1c04242c60df3517e20a6e35ca0ca8b65cbfb428 --- /dev/null +++ b/msigdb_gocc/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d8b78995b200d5683ce8ecfe7e2c6cad0cba0ececb09218044bdf1b6e6d121c +size 140413 diff --git a/msigdb_gocc/basic/plot_44.png b/msigdb_gocc/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..df2d5cd61eadc1cd28192e4319a0ab70b6f7fa7f --- /dev/null +++ b/msigdb_gocc/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc64a763732ca744cc656a6b06622cb13aa14a0c46d655d09792d21383a9a673 +size 140217 diff --git a/msigdb_gocc/basic/plot_45.png b/msigdb_gocc/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..ccc099292b2a62aad1597ae47c7229ba5a3ffc66 --- /dev/null +++ b/msigdb_gocc/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d1e1ac2aad45b39def5f98405f80493252c8036aa3b4d71d19b588463fc3c159 +size 146542 diff --git a/msigdb_gocc/basic/plot_46.png b/msigdb_gocc/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..438d676a9c22eab5cf20a9aba1526ca6afed281e --- /dev/null +++ b/msigdb_gocc/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a34630f22cca21c230d26b61b7b67f5367ef6343b36f9580ac97d288f2d07bdd +size 144610 diff --git a/msigdb_gocc/basic/plot_47.png b/msigdb_gocc/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..175773ac08ee5dc8f153c522e4542a581fee7159 --- /dev/null +++ b/msigdb_gocc/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d149872c92f8247a5804fdffd20c8afd3ec16ea5953ce004ed324163075df29 +size 146340 diff --git a/msigdb_gocc/basic/plot_48.png b/msigdb_gocc/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..56366dab4a552d0349965db7c31e948cd8a2a8ce --- /dev/null +++ b/msigdb_gocc/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cc14b90d30430e7ad78fe34bca21bbbe8c188b11a89d03d358713114a12af108 +size 150320 diff --git a/msigdb_gocc/basic/plot_49.png b/msigdb_gocc/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..11ec01f3e525c2f11f1dc0fc111ad6c193c6454f --- /dev/null +++ b/msigdb_gocc/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bc39abf1d21be79b91d4b14b7e20a39ae4f7d4dff619ef35ea9b276bee495135 +size 149746 diff --git a/msigdb_gocc/basic/plot_5.png b/msigdb_gocc/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..0560d2691184efdc19ad72de365924c6abdc1719 --- /dev/null +++ b/msigdb_gocc/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2209fd11ca9543dd62ec41bcba9ae6fc02806de6a33764991b41356c84f8cdfe +size 146781 diff --git a/msigdb_gocc/basic/plot_6.png b/msigdb_gocc/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d9a3c80dbc59ae569c8e0f15ed12521b2d13fc7b --- /dev/null +++ b/msigdb_gocc/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6450f1d6172f3853232961d6f09320f5dc39209faf7f5cab7d870d79ca3a794c +size 139587 diff --git a/msigdb_gocc/basic/plot_7.png b/msigdb_gocc/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..062bcc8c3940d9b6b39bef3be13a31317d727a4b --- /dev/null +++ b/msigdb_gocc/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:32e0e293c9680301d0a1028f9e287c8b674e7a16b4b5a00a2e7088135236dd09 +size 144868 diff --git a/msigdb_gocc/basic/plot_8.png b/msigdb_gocc/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..498fbe6de6ad4f6b7f70797ea3152f0fb1a9b2ce --- /dev/null +++ b/msigdb_gocc/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6d0c48566be08602660398ec30cf4275ddf5bf48d30fb82029b50e98f896891 +size 135337 diff --git a/msigdb_gocc/basic/plot_9.png b/msigdb_gocc/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..15775c8163ac44b7be7d6bc6c29ced0947b0fde5 --- /dev/null +++ b/msigdb_gocc/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43e26d28ffdc76504f70a4f6466e69f0496a90610517002ef06601b8101084c7 +size 143854 diff --git a/msigdb_gocc/consensus.joblib b/msigdb_gocc/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..99dc63a2edde481f7aac18dfbd131569d564857d --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c4745b8abd0363fba6952cc91c038abd326027b6222caecc307b97699a37418 +size 149026 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..46d2647c4209bd0debbaf5b06c9f78fc996a43ef --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,24 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nuclear outer membrane endoplasmic reticulum membrane network 108 262 6.186626389046957 6.146540687206506e-10 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 5.602268538151958e-10 3.0789681733403155e-05 2.2300466683878464e-08 4.236413888379707e-14 1.721621459492293e-26 +Organelle subcompartment 109 313 5.627956853434282 1.823566862528873e-08 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 2.61776913612644e-08 0.0001040884367284 2.154940747734648e-07 1.1580701475459463e-10 4.983315903723454e-18 +Endoplasmic reticulum 149 407 5.59224887018247 2.2414722055415797e-08 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 7.155335984690982e-08 0.0031895953463959 1.550483710300823e-06 2.2283764544733137e-11 8.310035303649849e-22 +Mitochondrial envelope 81 263 5.014158529085452 5.326605723193338e-07 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 1.7679473547122283e-16 2.1778442080805034e-10 1.3117994566590616e-10 1.181049740909699e-14 1.1495628256874181e-17 +Envelope 112 425 4.917891629109039 8.74813173239061e-07 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 4.2599028005160745e-17 5.65377522753309e-09 1.6950221025689017e-12 1.4085418493193533e-15 2.766661681773376e-21 +Intrinsic component of organelle membrane 56 109 4.77646256028133 1.7840575103900136e-06 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 0.0001729321569991 0.0027217046165537 0.0001283930384216 3.2846794740631988e-06 6.750702420855934e-13 +Organelle inner membrane 60 209 4.556261201441363 5.20721767682808e-06 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 6.043534095057011e-13 7.18909174359896e-07 8.598458053211164e-10 3.0440157987343395e-11 3.032383535631773e-14 +Membrane protein complex 75 259 4.121848434269405 3.75844460487329e-05 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 6.415887359779165e-06 8.423078084060036e-06 1.4125833357799697e-05 5.347804606738824e-07 1.9322861899182823e-10 +Mitochondrial protein containing complex 20 139 3.2577045557655726 0.0011231727587839 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 3.9771315494108666e-08 2.2745072988397365e-07 1.1523760892180409e-07 1.978352808444242e-07 2.272949686816068e-07 +Inner mitochondrial membrane protein complex 37 69 2.761569373064116 0.0057524294380617 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 1.8107629485150177e-08 3.3004639644405576e-05 4.546126432246246e-07 1.5626928598434242e-08 7.149111845568422e-10 +Mitochondrion 101 533 2.6263420888845603 0.0086308028622161 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 7.314487358993236e-11 3.929323194805106e-06 3.0307204855298757e-05 1.0174578925562202e-12 6.661678935282673e-13 +Tim23 mitochondrial import inner membrane translocase complex 3 6 2.458885766621401 0.0139368955581689 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.0088507375273171 0.0011617774889038 0.0046590638338273 9.399325491902678e-05 0.0013781701696679 +Golgi membrane 33 109 2.2225032324862277 0.0262493158225287 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.4956827550873697 0.3234724753330111 0.2176248359113487 0.5732849956792068 0.008896134421103 +Intrinsic component of endoplasmic reticulum membrane 25 44 2.13966572206906 0.0323817911157224 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 0.0013945096505443 0.0212801192322264 0.0012481565311226 4.881808377102356e-05 3.159203327889139e-08 +Proteasome core complex beta subunit complex 3 7 2.1374938772718277 0.032557843183733 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 0.0058945182768218 0.04159641685533 0.003087611696091 0.0010341818226167 0.0005688349419973 +Proton transporting v type atpase complex 2 11 2.1073810897460548 0.0350845594353308 3.1723300970873787 11.17233009708738 1.083137374920517 0.3054753623634815 1.8106779848505148 1.1913569842207026 0.9186852151104662 0.2868810804648729 0.0207808863220497 0.0028214739728005 0.0111011801010317 0.0072626368836444 0.0465653262864464 +Ciliary transition zone 0 5 2.099137888108178 0.0358047473694405 1.9635922330097089 6.907766990291262 0.9295898692526422 0.3532985326295446 1.5457849700174688 1.7711928579014855 0.854807445224746 0.2896111184937897 0.5008531752546105 0.2180755491779121 0.3924527927004838 0.7186004308696157 0.9253181096180496 +Outer membrane 19 74 2.0767307552738195 0.0378264163470642 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 1.0943201266948905e-07 0.0001903287561044 0.000317870383057 1.5828240095211134e-06 2.1295337549166104e-05 +Pore complex 2 9 2.0153349627369845 0.0438695639252668 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0013474758590725 0.0028214739728005 0.0111011801010317 0.0072626368836444 0.0078812527225172 +Postsynaptic cytosol 1 5 2.00716144663543 0.0447324752348679 1.0655339805825244 5.839805825242719 0.6842461209696534 0.4705435342470324 1.4888180156744395 0.7231054665083247 0.8090294271856947 0.3031424553191165 0.1248399455976769 1.0 1.0 0.0227865880642579 0.0817606313480972 +Lumenal side of endoplasmic reticulum membrane 4 7 1.9879037403651372 0.0468223370073579 3.0776699029126213 7.361650485436893 0.5475818769285827 0.3637002691484017 1.5990854205757892 0.8689828861838115 1.1522443815379428 0.2937666584254462 1.0 1.0 1.0 0.0683566835720805 0.0013369974246366 +Intrinsic component of golgi membrane 6 9 1.9830711423287064 0.0473594834799622 4.655339805825243 10.08495145631068 1.3178763872097854 0.2129685736028588 2.6046347098798024 1.9780511021437377 1.2704958978874823 0.2699640456705705 0.1064120376614914 0.1801156574188796 0.0603249601752956 0.2676442975527425 0.051296284939533 +Cytoplasmic ubiquitin ligase complex 4 7 1.9721595971097456 0.0485913903084735 2.483009708737864 7.910194174757281 0.4696225379870448 0.4249570308862076 1.3355492924362993 1.5900763128676454 0.9748020228745546 0.2768294000718119 1.0 1.0 1.0 0.2887519731811417 0.0003671727016274 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..041d5bce76ecc29f96e4943bb77dbbc43dcdb32e --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 895, + "title": "Average number of proteins per term", + "value": 26.06927374301676 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fa36edf66af1649f78c44b1538c7cfc65c45f3d9 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7347313b9691f751ccbcc7a40666afa14b935034 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,217 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nuclear outer membrane endoplasmic reticulum membrane network 0.6171343886230647 6.186626389046957 6.146540687206506e-10 5.501152412556029e-07 5.501153923999825e-07 262 O60725,Q9NQC3,Q8N511,Q9HD20,Q9BQE5,P43307,O95197,Q86XL3,Q15392,P30519,Q9Y282,O15269,Q9BRR6,Q9P2W9,Q16850,P51648,Q96N66,Q9Y5M8,O95772,Q4ZIN3,Q5BJF2,Q8TB61,Q15629,Q99720,O75844,O95470,Q15800,P09601,Q96GC9,Q96G23,P67812,O43852,O00264,P07099,Q06136,O43865,P01889,Q9BZF3,P53992,Q96RQ1,Q8NF37,Q9NZ01,Q96HY6,Q96CS3,O15260,O43292,P16615,Q96A33,Q15005,Q96KC8,Q8TCT9,Q86UE4,Q9BT22,O15027,P55735,Q9Y6K0,Q9Y3B3,P16435,Q14534,Q99943,P50402,Q9P035,O14681,O76024,P46977,Q70UQ0,Q9BUN8,Q07065,P10321,Q9UBU6,Q10472,O95070,Q5VV42,Q9NZ08,Q9H3N1,Q13555,P04843,Q13190,Q9NTJ5,Q9Y4P3,Q9UGP8,Q12907,P48449,P51809,Q15363,Q9GZP9,P37268,Q9Y679,Q9Y320,P62942,Q15041,Q9Y678,Q96PC5,Q6RW13,Q15042,P38435,Q9BZF1,Q8N5M9,P49755,P04439,Q9Y3A6,Q9UKR5,Q96AG4,P35613,Q8TD16,P27824,Q9HCU5,Q9BVK6 108 +Organelle subcompartment 0.5553410462702112 5.627956853434282 1.823566862528873e-08 1.6320790383791385e-05 6.6870587468307114e-06 313 O60725,Q9NQC3,Q8N511,Q9HD20,Q9BQE5,P43307,O95197,Q86XL3,Q15392,P30519,Q9Y282,O15269,Q9BRR6,Q9NPR9,O00461,Q9P2W9,Q16850,P51648,Q96N66,Q9Y5M8,O95772,Q4ZIN3,Q5BJF2,Q8TB61,Q15629,Q99720,O75844,O95470,Q15800,P09601,Q96GC9,Q96G23,P67812,O43852,O00264,P07099,Q06136,O43865,P01889,Q9BZF3,P53992,Q96RQ1,Q8NF37,Q9NZ01,Q96HY6,Q96CS3,O15260,O43292,P16615,Q96A33,Q15005,Q96KC8,Q8TCT9,Q86UE4,Q9BT22,O15027,P55735,Q9Y6K0,Q9Y3B3,P16435,Q14534,Q99943,P50402,Q9P035,O14681,O76024,P46977,Q70UQ0,Q9BUN8,Q07065,P10321,Q9UBU6,Q10472,O95070,Q5VV42,Q9NZ08,Q9H3N1,Q13555,P04843,Q13190,Q9NTJ5,Q9Y4P3,Q9UGP8,Q12907,P48449,P51809,Q15363,Q9GZP9,P37268,Q9Y679,Q9Y320,P62942,Q15041,Q9Y678,Q96PC5,Q6RW13,Q15042,P38435,Q9BZF1,Q8N5M9,P49755,P04439,Q9Y3A6,Q9UKR5,Q96AG4,P35613,P27824,Q9HCU5,Q9BVK6 109 +Endoplasmic reticulum 0.5179082059256158 5.59224887018247 2.2414722055415794e-08 2.006097524126999e-05 6.6870587468307114e-06 407 Q6P179,O60725,P50851,Q9NQC3,P18031,Q8N511,Q9HD20,Q9BQE5,P57088,P43307,O95197,Q86XL3,P05023,Q15392,Q9Y673,P30519,Q9H6E4,Q9Y282,O15269,Q8N2K0,Q5JRA6,O00429,Q9BRR6,O95456,O15173,Q9P2W9,Q16850,P51648,Q96N66,Q9Y5M8,O95772,Q4ZIN3,Q5BJF2,P80303,Q8TB61,Q15629,Q99720,Q14257,O75844,O95470,Q15800,P09601,Q32P28,Q96GC9,Q96G23,P67812,O43852,O00264,P07099,Q9UQB8,Q06136,O43865,P01889,P84157,Q96AY3,Q9BZF3,P53992,Q96RQ1,Q8NF37,Q9NZ01,Q96HY6,Q96CS3,O15260,O43292,P16615,P42858,Q96A33,Q15005,Q96KC8,Q8TCT9,Q86UE4,P13674,Q92791,Q9BT22,O15027,P55735,P48723,Q9Y6K0,Q9Y3B3,P16435,Q14534,Q99943,P50402,Q9UMX5,Q9P035,Q9Y217,O60506,O14681,O76024,P46977,Q70UQ0,Q9BUN8,Q07065,P30536,P10321,Q9UBU6,Q10472,O95070,O43390,O75718,Q5VV42,Q9NZ08,Q9H3N1,Q13555,P04843,Q13190,Q9NTJ5,Q9Y4P3,Q9UGP8,Q12907,P48449,P51809,Q02750,Q15363,Q8TED1,Q13217,Q9GZP9,Q15293,P37268,Q9Y679,Q9Y320,Q01105,P62942,O15118,Q15041,Q9Y678,Q96PC5,Q6RW13,Q15042,Q8IXB1,P52789,P38435,Q9BZF1,Q8N5M9,P49755,P04439,Q9Y3A6,Q9UKR5,Q96AG4,P35613,P27824,Q9HCU5,Q9BVK6,Q92604,O95881,Q9UBS4,Q8NFQ8,Q9UM00,Q9NPA0 149 +Mitochondrial envelope 0.5329338743169727 5.014158529085452 5.326605723193338e-07 0.0004766177208656 0.0001191828030566 263 Q99595,Q9NS69,O60830,Q70HW3,O43676,P52888,O43169,P21796,Q567V2,P03886,Q8N4H5,P23786,P45880,Q9H2D1,P14406,O75964,Q8N2A8,Q9Y2R0,O95831,Q13423,Q9BPX6,Q9UBX3,Q13505,Q96A26,Q9UDW1,Q9Y6M9,O14949,Q8WY22,O43772,Q9H061,P09601,Q96CU9,Q9BUK6,Q9Y6C9,Q6DKK2,Q6P4A7,Q9Y277,O00264,Q8IYU8,Q9Y619,Q96AY3,O60313,Q15070,Q9NR28,Q15388,P47985,O14925,O96000,Q07820,Q00325,Q3ZCQ8,Q9BYT8,O75880,Q9NZJ7,O43819,Q709F0,Q96BR5,P30536,P00403,P82933,P24539,Q7KZN9,Q9HC21,Q8NBN7,Q9UJS0,Q9NVI7,O75306,Q8TB36,Q5T9A4,Q9Y320,P13073,P12235,P36404,P36551,P56134,O15228,Q9BXK5,Q9Y4W6,P54886,Q9P0J0,P52789 81 +Envelope 0.4761282480639262 4.917891629109039 8.74813173239061e-07 0.0007826517007819 0.0001565915580099 425 Q99595,Q9NS69,O60830,Q70HW3,O43676,P52888,Q9NQC3,O43169,P21796,Q567V2,P03886,Q8N4H5,P23786,P45880,Q9H2D1,P14406,Q9H1E5,O75964,Q8N2A8,Q9Y2R0,Q99543,O95831,O15173,Q13423,Q9BPX6,Q9UBX3,P07437,Q13505,Q96A26,Q5BJF2,P80303,Q9UDW1,Q99720,Q9Y6M9,O75844,Q9BTX1,O14949,Q8WY22,O43772,Q9H061,P09601,Q96CU9,Q9BUK6,Q9Y6C9,Q6DKK2,Q6P4A7,Q9Y277,O00264,Q8IYU8,Q9Y619,Q96AY3,Q9BZF3,Q8NFH4,O60313,Q15070,Q9NR28,Q15388,P47985,O14925,O96000,Q99829,Q96KC8,Q86UE4,Q07820,Q00325,Q3ZCQ8,P55735,Q9BYT8,Q9Y6K0,O75880,P50402,Q14728,Q9P035,Q9Y217,Q9NZJ7,O43819,O14681,Q709F0,Q96BR5,P30536,P00403,P82933,P24539,O75179,P42167,Q6ZRP7,Q7KZN9,P42166,Q9HC21,Q8NBN7,Q8N1F7,Q9UJS0,P67809,Q9NVI7,O75306,Q8TB36,Q5T9A4,Q9Y320,P13073,P12235,P62995,P36404,O15118,P36551,P56134,O15228,Q9BXK5,Q9Y4W6,P54886,Q9P0J0,P52789,P06576 112 +Intrinsic component of organelle membrane 0.6426057940148745 4.77646256028133 1.7840575103900136e-06 0.0015954587963837 0.0002661219119666 109 Q99595,O75880,O60830,P12235,Q9P035,Q9NQC3,O43819,Q9NX63,O15118,O76024,P57088,Q15041,Q86XL3,Q9BUN8,P01889,P20020,P10321,Q9Y282,Q9H3K2,Q9Y2R0,Q9Y4W6,O95070,O15258,Q9Y287,Q9NZ01,Q9NVH1,Q9BPX6,Q15070,O43292,Q6ZRP7,Q15388,Q13505,P04439,O14925,Q9HC21,Q9Y4P3,L0R6Q1,Q96A33,Q8TB61,Q15629,Q8TCT9,Q6UXV4,P27824,O75844,Q9HCU5,P42892,O95470,Q8TB36,Q9GZP9,Q00325,Q53H12,Q9Y679,Q9Y512,Q6P4A7,Q9UM00,Q9NPA0 56 +Organelle inner membrane 0.5398021787666245 4.556261201441363 5.20721767682808e-06 0.0046496288066669 0.0006657799743945 209 Q99595,O75880,O60830,Q70HW3,P50402,O43676,Q14728,Q8IYU8,P13073,P12235,P62995,O43819,Q567V2,P03886,P23786,Q709F0,Q9Y619,P36551,P56134,Q9H2D1,P14406,Q9H1E5,O75964,P00403,Q9Y2R0,Q9Y4W6,P82933,P54886,P24539,Q9P0J0,O95831,Q13423,Q9BPX6,Q9UBX3,Q15070,O60313,Q7KZN9,P47985,Q13505,O14925,Q9HC21,Q8NBN7,O96000,Q9UDW1,Q99720,Q9UJS0,Q9Y6M9,O75844,O14949,Q9NVI7,O43772,O75306,Q9H061,Q00325,Q5T9A4,Q3ZCQ8,Q96CU9,Q9Y6C9,Q6DKK2,Q6P4A7 60 +Membrane protein complex 0.4765365519250374 4.121848434269405 3.75844460487329e-05 0.0330792209711028 0.0042047599017021 259 Q99595,Q9NS69,O60830,P67812,P13073,O43676,P12235,Q8IYU8,Q01650,P62942,P21796,Q8N511,P49327,P03886,Q8N4H5,P46977,Q15041,P45880,P01889,Q9BUN8,P14406,P56134,Q9Y487,P10321,O75964,Q9UBU6,P00403,O15269,P53992,Q9Y678,Q9Y4W6,Q93050,P24539,Q9P0J0,Q9P2W9,Q96CS3,Q9Y5X3,P06576,Q9BPX6,O43292,Q9NR28,Q15388,P47985,P49755,P04843,Q13505,P04439,O14925,Q9Y5M8,Q13190,O96000,Q9UGP8,Q07666,Q9UDW1,Q15005,Q4KMQ2,Q8TCT9,Q6UXV4,Q9Y6M9,P51809,O14949,Q5T2T1,O75306,Q9GZP9,Q9UJX6,Q3ZCQ8,P55735,Q53H12,Q96CU9,Q9Y3B3,Q9Y679,Q9Y512,Q9Y2T2,Q9Y375,Q9Y277 75 +Mitochondrial protein containing complex 0.4726496067533781 3.2577045557655726 0.0011231727587839 0.6342497556691187 0.091385419919238 139 Q99595,Q9NS69,O60830,O43676,Q8IYU8,P21796,Q567V2,P03886,Q8N4H5,P14406,O75964,Q9BPX6,Q15388,P47985,Q13505,O14925,Q9UDW1,Q9Y6M9,O14949,Q96CU9 20 +Uniplex complex 0.952313167259789 2.7931425287881715 0.0052198686886486 0.9907581954928548 0.1505225293889921 2 Q9BPX6 1 +Inner mitochondrial membrane protein complex 0.6430626567997687 2.761569373064116 0.0057524294380617 0.9942771557745884 0.1505225293889921 69 Q99595,P13073,O60830,O43676,Q8IYU8,Q9NX63,P03886,P36542,P56134,P14406,P00403,O75964,Q9Y4W6,P24539,Q9NVH1,Q9P0J0,P06576,P56385,Q9BPX6,P47985,Q13505,O14925,Q96IX5,O96000,P21912,Q9UDW1,P15954,Q6UXV4,Q9Y6M9,P12236,O14949,O75306,Q3ZCQ8,Q53H12,Q96CU9,Q9Y512,Q9Y375 37 +Mitochondrion 0.3707424971504177 2.6263420888845603 0.0086308028622161 0.99957273077038 0.1639639525815371 533 Q99595,Q9NS69,O60830,Q70HW3,O43676,P52888,Q9NPH0,O43169,P21796,Q567V2,P03886,Q8N4H5,P23786,P45880,Q9H2D1,P14406,O75964,Q8N2A8,Q9Y2R0,O95831,Q13423,Q9BPX6,Q9UBX3,Q3SXM5,Q13505,Q96A26,Q9UDW1,Q9Y6M9,O14949,Q99417,O00116,Q8WY22,O43772,Q9H061,P09601,P48735,O75648,Q8NBX0,Q96CU9,Q9BUK6,Q9Y6C9,Q6DKK2,Q6P4A7,Q9HC38,Q9Y277,O00264,Q8IYU8,Q08J23,Q9NUJ1,Q9Y619,Q5JTZ9,Q92947,Q96AY3,O43823,Q16740,Q5TC12,O60313,Q15070,O43292,Q9NR28,Q15388,P47985,O14925,O96000,P13674,Q9BQP7,Q9H3L0,Q9BY49,Q07820,Q00325,Q5JRX3,Q3ZCQ8,Q15120,P48723,Q9BYT8,P16435,O75880,Q9UMX5,Q9NZJ7,O43819,Q709F0,Q96BR5,Q9BWD1,P30536,P00403,Q9NUQ9,Q5JPH6,P82933,Q9H7Z7,P24539,Q7KZN9,O75874,Q9HC21,Q8NBN7,Q8N6R0,P30837,Q9UJS0,Q02750,Q9NVI7,O75306,Q8TB36 101 +Excitatory synapse 0.908086793723443 2.607076797994964 0.0091318876224628 0.9997282385273798 0.166796722900087 4 Q9UQB8 1 +Extrinsic component of endosome membrane 0.889996440014244 2.5343754560209577 0.0112647962512151 0.9999604999464612 0.1867035674969914 3 P04083,P40818 2 +Signal peptidase complex 0.8781243273048128 2.484584254378203 0.0129702811333558 0.999991575286454 0.1903016658090736 3 P67812 1 +Tim23 mitochondrial import inner membrane translocase complex 0.8739912896547406 2.458885766621401 0.0139368955581689 0.999996494785186 0.1924311423522245 6 Q99595,O60830,O14925 3 +Hrd1p ubiquitin ligase erad l complex 0.8661445354218572 2.434037644556648 0.014931442112277 0.9999985793759236 0.1924311423522245 3 Q9BUN8,Q9GZP9 2 +Er ubiquitin ligase complex 0.8664529914529929 2.4319335152820147 0.0150184637809713 0.9999986873764743 0.1924311423522245 4 Q9UBU6,Q9GZP9,Q9BUN8 3 +Vacuolar proton transporting v type atpase v0 domain 0.8609910962516707 2.4121994364185153 0.0158566052584179 0.9999993872943737 0.1924311423522245 3 Q9Y487 1 +Proton transporting v type atpase v0 domain 0.8609910962516707 2.4121994364185153 0.0158566052584179 0.9999993872943737 0.1924311423522245 3 Q9Y487 1 +Dendrite membrane 0.854092526690391 2.3870205418068706 0.0169855421741069 0.9999997806612986 0.1924311423522245 2 Q14168 1 +Zymogen granule membrane 0.8409252669039138 2.331029783270914 0.0197517892664529 0.999999982389482 0.2115302043533301 2 Q15363 1 +Mhc protein complex 0.8394446422214354 2.3202786677099696 0.0203258073456831 0.9999999895746038 0.2115302043533301 3 P01889,P10321 2 +Mhc class i protein complex 0.8394446422214354 2.3202786677099696 0.0203258073456831 0.9999999895746038 0.2115302043533301 3 P01889,P10321 2 +Golgi membrane 0.4157426125654713 2.2225032324862273 0.0262493158225287 0.9999999999542112 0.2310845384807682 109 O95197,P01889,Q15392,P10321,Q9Y678,Q8IZA0,Q9Y282,Q10472,O95070,Q6RW13,Q8NF37,Q9Y287,Q9H7Z7,Q9BW83,O00461,Q9P2W9,O15260,Q7LGA3,Q6ZRP7,P49755,P04439,Q13190,Q9NTJ5,L0R6Q1,P35613,Q12907,Q8TB61,Q92896,Q15363,Q9BVK6,O15027,Q8IUD2,Q9Y3B3 33 +Mitochondrial crista 0.8153024911032143 2.2210137674068577 0.0263500289267462 0.9999999999582596 0.2310845384807682 2 O60313 1 +Derlin 1 retrotranslocation complex 0.8124286269753944 2.2036180137573615 0.0275512193478093 0.999999999986173 0.232625861474428 3 Q8TCT9 1 +Phagocytic cup 0.809735057161672 2.1873566220039127 0.0287165002197384 0.999999999995272 0.2387435919391023 4 P04083 1 +Intrinsic component of endoplasmic reticulum membrane 0.7188003915051949 2.1396657220690596 0.0323817911157224 0.9999999999998396 0.2387435919391023 44 Q9P035,Q9NQC3,O76024,Q15041,Q86XL3,Q9BUN8,P01889,P10321,Q9Y282,Q9NZ01,O43292,P04439,Q9Y4P3,Q96A33,Q8TB61,Q15629,Q8TCT9,P27824,O75844,Q9HCU5,O95470,Q9GZP9,Q9Y679,Q9UM00,Q9NPA0 25 +Proteasome core complex beta subunit complex 0.8004648991587813 2.1374938772718273 0.032557843183733 0.9999999999998638 0.2387435919391023 7 P49721,P28074,P28072 3 +Mitochondrial permeability transition pore complex 0.7951105518616945 2.123173059735743 0.0337393526025457 0.9999999999999544 0.2415737646342279 4 P21796 1 +Proton transporting v type atpase complex 0.7935955552237162 2.1073810897460548 0.0350845594353308 0.9999999999999868 0.2448553835972373 11 Q8N511,Q9Y487 2 +Histone pre mrna 3 end processing complex 0.7886600156707325 2.0996912469329474 0.035756010072488 0.999999999999993 0.2448553835972373 3 O60506 1 +Outer membrane 0.5181150217647454 2.0767307552738195 0.0378264163470642 0.999999999999999 0.2493176982716807 74 P50402,Q9NS69,O00264,Q9NZJ7,O43169,P21796,Q8N4H5,P45880,Q8N2A8,O60313,Q15388,Q13505,Q99720,Q8WY22,Q07820,P09601,Q9BUK6,Q9Y6C9,Q9Y277 19 +Pore complex 0.7736575313850493 2.0153349627369845 0.0438695639252668 1.0 0.2707811014697506 9 P45880,P21796 2 +Dendritic shaft 0.7679002034337523 2.007944211110813 0.0446492203838724 1.0 0.2723507845932433 3 Q9UQB8 1 +Postsynaptic cytosol 0.7700351647297786 2.00716144663543 0.0447324752348679 1.0 0.2723507845932433 5 Q9UQB8 1 +Lumenal side of endoplasmic reticulum membrane 0.7671760575290898 1.9879037403651376 0.0468223370073579 1.0 0.2753001419030545 7 Q8TCT9,P01889,P04439,P10321 4 +Intrinsic component of golgi membrane 0.76659962282485 1.9830711423287064 0.0473594834799622 1.0 0.2753001419030545 9 Q9Y282,O95070,O15258,L0R6Q1,Q8TB61,Q6ZRP7 6 +Cytoplasmic ubiquitin ligase complex 0.7637026029856621 1.972159597109746 0.0485913903084735 1.0 0.2753001419030545 7 Q9UBU6,Q9GZP9,Q8TEY7,Q9BUN8 4 +Er membrane insertion complex 0.7574576376735664 1.9614550672446496 0.0498259616337095 1.0 0.2804668909570443 3 P46379 1 +Tor complex 0.7434163701067595 1.9049563692517408 0.0567857428658031 1.0 0.298024116775071 2 Q9Y4R8 1 +Torc1 complex 0.7434163701067595 1.9049563692517408 0.0567857428658031 1.0 0.298024116775071 2 Q9Y4R8 1 +Micos complex 0.7297008547008526 1.8306263708733184 0.0671563296876347 1.0 0.3274035711243452 4 Q6UXV4,Q9NX63,Q5XKP0 3 +Cis golgi network 0.731182814890057 1.821292123305514 0.0685624631402006 1.0 0.3313871693504643 8 P49755,O00461,Q9NPR9 3 +Postsynaptic density membrane 0.7225868208670818 1.798289269172418 0.0721311793602641 1.0 0.3397758185654548 4 Q99720 1 +Integral component of synaptic vesicle membrane 0.7217220938337445 1.794352013634455 0.0727570009674254 1.0 0.340929402438983 4 O76024 1 +Proteasome core complex 0.7219933483501126 1.7758934622584626 0.0757504787432912 1.0 0.3409830060270248 14 P49721,P60900,P28072,P28074 4 +Proton transporting two sector atpase complex proton transporting domain 0.7193471658740569 1.7644049191338982 0.0776638305754287 1.0 0.3458165590298939 9 O75964,Q93050,P24539,P56385,P56134,Q9Y487 6 +Mcrd mediated mrna stability complex 0.712573439169691 1.7464943453696935 0.0807250887989352 1.0 0.3473507426684954 5 O60506,Q9H074 2 +Zymogen granule 0.7054451458121076 1.7266657229846556 0.0842277149973425 1.0 0.3560560955927391 3 Q15363 1 +Intrinsic component of mitochondrial inner membrane 0.6917816772488424 1.6911983996860929 0.0907989165621432 1.0 0.3668719221764079 27 Q99595,O75880,O60830,Q9H3K2,Q9Y2R0,Q13505,Q9Y4W6,O14925,Q9HC21,O43819,Q9NX63,Q00325,Q53H12,Q6UXV4,Q9Y512,Q6P4A7,Q15070 17 +Inflammasome complex 0.6868327402135241 1.6489348948657452 0.0991609733543084 1.0 0.3792695348380599 2 Q9H6R0 1 +Nlrp3 inflammasome complex 0.6868327402135241 1.6489348948657452 0.0991609733543084 1.0 0.3792695348380599 2 Q9H6R0 1 +Pole plasm 0.6870772516909907 1.6425472640621437 0.1004766395301173 1.0 0.3801966519915671 3 P42694,Q9HCE1 2 +Intrinsic component of mitochondrial membrane 0.6525559644270508 1.636787130150441 0.1016749557795462 1.0 0.3801966519915671 39 Q99595,O75880,P12235,O60830,O43819,Q9NX63,Q9H3K2,Q9Y2R0,Q9Y4W6,Q9BPX6,Q15070,Q15388,Q13505,O14925,Q9HC21,Q6UXV4,Q8TB36,Q00325,Q53H12,Q9Y512,Q6P4A7 21 +Respirasome 0.6476897317844045 1.626865353985694 0.1037656976812619 1.0 0.3821823021593805 40 P00403,Q7KZN9,P47985,O14949,O43676,O75306,O96000,P03886,Q9UDW1,Q96CU9,Q13423,Q6DKK2,P14406,Q9Y6M9 14 +Postsynaptic recycling endosome 0.6800711743772236 1.6179591469596666 0.1056714021477793 1.0 0.3827140487383184 2 P20338 1 +Calcium channel complex 0.6864041922541219 1.6155896311497089 0.1061830672050954 1.0 0.3827140487383184 7 Q9BPX6,Q8IYU8 2 +Mitochondria associated endoplasmic reticulum membrane 0.6845966739902122 1.6037116974896637 0.108777616277814 1.0 0.3863332006692204 8 Q15388,Q96N66,O43865,P27824,Q9Y320 5 +Cul4a ring e3 ubiquitin ligase complex 0.6747330960854141 1.5934525278530032 0.1110587099017506 1.0 0.3913289187482944 2 Q92990 1 +Outer mitochondrial membrane protein complex 0.680001737842673 1.5740986029882569 0.1154646555007823 1.0 0.3950978125507692 16 Q9NS69,Q8N4H5,Q13505 3 +Respiratory chain complex iii 0.676820585909965 1.5670261205445744 0.1171085862622913 1.0 0.3985254171283299 8 O14949,Q9UDW1 2 +Endoplasmic reticulum tubular network 0.670776981743654 1.5384490981180718 0.1239388452880412 1.0 0.4170122801984845 8 Q9NQC3,P50402 2 +Chromaffin granule membrane 0.6597864768683325 1.524602823503589 0.1273581927328506 1.0 0.4200433862650465 2 P20073 1 +Chromaffin granule 0.6597864768683325 1.524602823503589 0.1273581927328506 1.0 0.4200433862650465 2 P20073 1 +Extrinsic component of organelle membrane 0.6676894366797475 1.5205378691850444 0.1283758486176596 1.0 0.4200433862650465 9 P04083,P40818,Q9Y5X3 3 +Gpi anchor transamidase complex 0.6611203054521458 1.5151368493364803 0.1297377515055859 1.0 0.4200433862650465 4 Q92643,O43292 2 +Lumenal side of membrane 0.6592446684002358 1.4802665517190907 0.1388021258775698 1.0 0.4318626417830187 9 Q8TCT9,P01889,P04439,P10321 4 +Intraciliary transport particle 0.6535439914781384 1.4798257112663935 0.1389197652061244 1.0 0.4318626417830187 4 Q7Z4L5 1 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.6522551455659651 1.4664292109682016 0.1425313932042822 1.0 0.4398813686821813 5 O75964 1 +Prefoldin complex 0.6502465995052078 1.4570104297706048 0.1451135012254309 1.0 0.4416782318615287 5 P61758,O15212,Q99471 3 +Proton transporting atp synthase complex coupling factor f o 0.6510511823743103 1.4538177273459554 0.1459968472913604 1.0 0.4416782318615287 6 O75964,P56134,P24539 3 +Organelle membrane contact site 0.654589367811184 1.448980707602152 0.1473429703567799 1.0 0.4425233505681812 13 Q15388,Q96N66,O95772,Q9NTJ5,O43865,Q9Y320 6 +Respiratory chain complex iv 0.6487766394108144 1.4269796944159536 0.1535857476297151 1.0 0.4489242701708105 10 P00403,P13073,P47985,P15954,P14406 5 +Epsilon dna polymerase complex 0.6368814524741935 1.4099983499321664 0.1585401701344446 1.0 0.4562490426698648 3 Q07864,Q9NR33 2 +Cation channel complex 0.6430235956861237 1.4026528413503154 0.1607203863518487 1.0 0.4570351711566379 9 Q9BPX6,P62942,Q8IYU8 3 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6389573563448476 1.3966300039307271 0.1625248628504936 1.0 0.4570351711566379 25 P49755,Q15363,Q9Y282,Q10472,Q13190,O95070,Q9Y3A6,Q96RQ1,Q8N511,Q12907,Q96GC9,Q9Y3B3,O15260 13 +Proton transporting two sector atpase complex 0.6424722195258338 1.39657687685452 0.1625408477543941 1.0 0.4570351711566379 21 O75964,Q93050,P56385,Q8N511,P61421,P24539,P06576,P36542,P56134,Q9Y487 10 +Myofilament 0.6354888408142754 1.39538899079417 0.1628985693843212 1.0 0.4570351711566379 4 P09493,P67936 2 +Striated muscle thin filament 0.6354888408142754 1.39538899079417 0.1628985693843212 1.0 0.4570351711566379 4 P09493,P67936 2 +Nadh dehydrogenase complex 0.6405942033835366 1.3839595699304803 0.1663708347408783 1.0 0.4600663553560796 20 P03886,Q9Y6M9,O43676,Q96CU9 4 +Presynaptic cytosol 0.6342228538085479 1.3817020598662697 0.1670632016656155 1.0 0.4600663553560796 5 Q9UQB8 1 +Cytochrome complex 0.6389596011157622 1.3706710487837264 0.1704775237390681 1.0 0.4650281184836188 17 P00403,Q7KZN9,O14949,P47985,Q9UDW1,P14406 6 +Myosin ii complex 0.6257759797764131 1.3498226692680628 0.1770728714693552 1.0 0.4682179391900438 4 P14649 1 +Mib complex 0.629900994571459 1.3359282442673808 0.1815727281317882 1.0 0.4682179391900438 10 Q13505,Q5XKP0,Q9NX63,Q9NVH1,O75431,Q6UXV4,Q9Y512 7 +Nuclear stress granule 0.620149519401938 1.331802802121888 0.1829249969444037 1.0 0.4691056511898034 3 P31483,Q92797 2 +Nuclear envelope 0.3320967671081106 1.3117644132152046 0.189599635627671 1.0 0.4750900049027639 166 P50402,Q14728,Q9P035,Q9Y217,Q9NQC3,O14681,Q9H1E5,Q9BZF3,Q99543,Q8NFH4,O75179,O15173,P42167,Q6ZRP7,P07437,P42166,Q5BJF2,P80303,Q99829,Q96KC8,Q86UE4,Q99720,Q8N1F7,O75844,Q9BTX1,P55735,Q9Y6K0 27 +Golgi apparatus 0.3143237669620087 1.3106988677719018 0.1899595213612148 1.0 0.4750900049027639 270 O43852,Q9UQB8,Q9NX40,P36404,O14681,O15118,Q8NEW0,P49327,Q99805,O95197,P01889,Q15392,P10321,Q9Y678,Q8IZA0,Q9Y282,O43823,Q8N2A8,Q8TEY7,Q10472,O95070,Q93050,Q96RQ1,Q8NF37,Q9Y287,Q9H7Z7,Q6RW13,Q9NPR9,Q9BW83,O95456,Q15042,O00461,Q9P2W9,Q5VW38,O15260,Q7LGA3,Q6ZRP7,P49755,P04439,Q13190,Q9Y3A6,Q9NTJ5,P42858,L0R6Q1,P80303,P35613,Q12907,Q8TB61,Q92896,Q8TD16,P51809,Q02750,Q15363,Q9BVK6,O15027,Q9UJX6,O14976,Q8IUD2,Q96PU5,Q9Y6K0,Q9Y3B3,Q9Y2T2,Q9UM00 63 +Nuclear membrane 0.3472068206844211 1.2847521158484487 0.1988789201583907 1.0 0.4863295998408734 98 P50402,Q14728,Q9P035,P62995,O14681,P56134,Q9H1E5,Q9BZF3,Q99543,O75179,Q9BZF1,Q6ZRP7,Q5BJF2,Q99829,Q96KC8,Q86UE4,Q8N1F7,Q99720,O75844,P67809,Q9BTX1,Q9Y6K0 22 +Oxidoreductase complex 0.5422382907810406 1.258939818452398 0.208052070088039 1.0 0.5009320150440167 53 P47985,O14949,O43676,O43169,O96000,P03886,Q9UDW1,Q96CU9,Q9Y6M9 9 +Transporter complex 0.5680530593821602 1.2572457769043124 0.2086646518208152 1.0 0.5009320150440167 46 P47985,O14949,O43676,Q8IYU8,P03886,Q9UDW1,Q96CU9,Q9BPX6,Q9Y6M9 9 +Ion channel complex 0.6148570062285604 1.2539462864703443 0.2098615295265813 1.0 0.5022087404446264 13 Q9BPX6,Q4KMQ2,P62942,Q8IYU8 4 +Copii coated er to golgi transport vesicle 0.6024953638340345 1.252032863384843 0.2105578892739563 1.0 0.5025314957338425 32 P49755,Q15363,Q9Y282,P53992,P04439,Q13190,O95070,Q9Y3A6,Q96RQ1,O15027,P55735,Q12907,Q9Y3B3,P01889,P10321 15 +Cytosolic region 0.599895231556836 1.2056227091777971 0.2279629989209275 1.0 0.5206101197884391 7 Q9UQB8 1 +Crd mediated mrna stability complex 0.5944287708711684 1.1856376643151674 0.2357654214056315 1.0 0.5280038660235267 6 O60506 1 +Nata complex 0.5772241992882516 1.1400697459309808 0.2542572450392706 1.0 0.5577456723287921 2 Q9BXJ9 1 +Proton transporting atp synthase complex 0.5865961082149939 1.1261603285394994 0.260097662126928 1.0 0.5650179796203897 10 O75964,P56385,P24539,P06576,P36542,P56134 6 +Nuclear pore outer ring 0.5841975626698626 1.1194283697651266 0.2629574335991038 1.0 0.5684707803652124 9 P55735,Q12769,Q8NFH4,Q9BW27 4 +Organelle envelope lumen 0.574926397511701 1.0889094126144463 0.2761938350361657 1.0 0.5843817549819581 31 Q96AY3,Q9NR28,P07437,Q8IYU8,P52888,O14925,O95831,Q9BYT8,Q9BPX6,O60313 10 +Messenger ribonucleoprotein complex 0.5711125952855488 1.083480079687826 0.278595388084921 1.0 0.5866891113788336 5 P51991,Q99729,P67809 3 +Copi coated vesicle 0.5766434016233378 1.0733444292185828 0.2831166078094353 1.0 0.5934177142609945 11 Q9Y678,Q15363,Q9Y3B3,Q8N511 4 +Endoplasmic reticulum golgi intermediate compartment 0.532467977630735 1.0685587552649989 0.285268541853674 1.0 0.5937566161838098 48 Q9Y678,P49755,Q9Y282,Q15363,Q10472,Q9Y217,Q13190,O95070,Q9Y3A6,Q96RQ1,Q8N511,P80303,Q12907,Q96GC9,Q9Y3B3,O15260 16 +Schaffer collateral ca1 synapse 0.5739705835507158 1.0561683383308975 0.2908913131927915 1.0 0.601264954520897 12 Q9UQB8,Q9BVA1 2 +Intrinsic component of peroxisomal membrane 0.558362989323842 1.0519580758015197 0.2928187848297354 1.0 0.6038544065037171 2 Q8WVX9 1 +Copi coated vesicle membrane 0.5706324981893012 1.0488381550356334 0.2942526134090117 1.0 0.6050860615888916 10 Q15363,Q9Y3B3,Q8N511 3 +Keratin filament 0.5551601423487473 1.0370195035131584 0.2997267677601587 1.0 0.6087759751233311 2 P58107 1 +Copii vesicle coat 0.5680428692559998 1.036310753964001 0.3000571907342086 1.0 0.6087759751233311 10 P55735,P53992 2 +Cornified envelope 0.5605481823396932 1.0335916539092376 0.3013271027705426 1.0 0.6087759751233311 5 P04083 1 +Sarcoplasmic reticulum membrane 0.5581546126703081 1.0000835189254986 0.3172700912809314 1.0 0.6296158130741323 8 Q13555,P16615 2 +Er to golgi transport vesicle membrane 0.557431447233185 0.9568508155070986 0.338642559459934 1.0 0.642200062024173 21 P49755,Q15363,P53992,Q13190,O15027,P55735,Q9Y3B3,P01889,P10321 9 +Chloride channel complex 0.5407276987733365 0.9498227388329368 0.3422023298103989 1.0 0.6461415299162595 4 Q4KMQ2 1 +Endoplasmic reticulum protein containing complex 0.4898195199077334 0.9447554853528188 0.3447837227634374 1.0 0.6480848952693765 55 P67812,P62942,P46977,Q15041,Q9BUN8,Q9UBU6,O15269,Q8IXB1,Q96CS3,O43292,P04843,P04439,Q9Y5M8,Q9UGP8,Q15005,Q8TCT9,P13674,Q9GZP9,Q9UBS4,Q9Y679 20 +Dendrite cytoplasm 0.5461242569498065 0.9305977181326464 0.3520616953142634 1.0 0.6480848952693765 10 Q9UQB8,P33176,P27824 3 +Myosin filament 0.5306049822064037 0.9229187597524304 0.3560495435426212 1.0 0.650518330756049 2 P35580 1 +Rough endoplasmic reticulum membrane 0.5483076999669474 0.922726599032911 0.3561497006373899 1.0 0.650518330756049 14 Q9Y5M8,Q96A33,Q5BJF2,Q9UGP8 4 +Anchored component of synaptic membrane 0.5241992882562179 0.8933262925669163 0.371682461721075 1.0 0.6719390627394377 2 Q15334 1 +Cul2 ring ubiquitin ligase complex 0.5273884132849721 0.8876391655155867 0.3747348790138209 1.0 0.6728965959715523 4 Q15369 1 +Vesicle membrane 0.3013227844526437 0.8863959215058252 0.3754042162022626 1.0 0.6728965959715523 230 Q14728,P04083,O00264,Q9NZJ7,P42785,Q8N511,Q9UIQ6,O43924,O15118,O76024,Q99805,P01889,P20020,Q07065,Q9Y487,P30519,P10321,Q9Y678,Q9BZF3,P53992,Q93050,Q8NF37,Q9Y287,O00461,P40818,Q9Y5X3,O15260,Q13555,Q13190,O95772,P42858,Q96L92,O43760,Q4KMQ2,Q99829,P51809,Q15363,O15027,Q5T9A4,P55735,Q96J02,Q9Y3B3,Q9Y2T2 43 +Spectrin associated cytoskeleton 0.5194019223923126 0.8607339840880389 0.3893845713942059 1.0 0.6887335798375777 3 Q12955,Q01082 2 +Nuclear inner membrane 0.5381548179721778 0.8578661999944958 0.3909663499344322 1.0 0.6888088251797576 21 Q99720,P50402,Q9H1E5,O75844 4 +Lipid droplet 0.5349934769139614 0.8527314707043318 0.3938082345439189 1.0 0.6924525931567925 28 Q01105,Q8NF37,O43760,Q8NBX0,P48449,Q96CS3,Q99720,Q9Y679,Q07065 9 +Coated vesicle 0.3316357056397643 0.8376282644259349 0.4022395135857484 1.0 0.7003975966133168 83 Q8N511,P01889,P10321,Q9Y678,Q9Y282,P53992,O95070,Q96RQ1,Q5VW38,P49755,P04439,Q13190,Q9Y3A6,Q12907,P51809,Q15363,Q9BVK6,O15027,P55735,Q9Y3B3 20 +Intraciliary transport particle b 0.5125913067383835 0.8293785772072174 0.4068902198468556 1.0 0.7057495092304957 3 Q9BW83 1 +Golgi cisterna membrane 0.526371807553369 0.8248772291302678 0.4094412953116486 1.0 0.7066348453562052 12 O00461,Q10472 2 +Rough endoplasmic reticulum 0.5202168981075025 0.776817230173947 0.4372666096923101 1.0 0.7301373426765253 29 P04843,Q9UQB8,Q9Y5M8,Q5BJF2,Q9UGP8,Q96A33,Q5VV42,Q15041,Q8TCT9,Q07065 10 +Golgi cisterna 0.5175235632851717 0.7726246641565062 0.4397445434302103 1.0 0.7329075723836839 14 Q15363,O00461,Q10472 3 +Vacuolar membrane 0.3076304469529752 0.7642108102844196 0.444741625458297 1.0 0.7343660926954417 108 P51809,Q9NZJ7,P42785,O95772,Q93050,Q8NF37,Q8N511,Q9UIQ6,O15118,P55735,Q99829,Q8NHS3,Q9Y2T2,O15260,Q96GC9,Q07065,Q9Y487,Q01650 18 +Intrinsic component of plasma membrane 0.4329964531381666 0.7614196996753175 0.4464064246980315 1.0 0.7343660926954417 63 P12235,O00264,Q9UIQ6,O15118,P36551,Q99805,P01889,P20020,P10321,O43657,P30825,P53985,Q9NR28,P16615,P04439,O43813,P15260,P35613,Q12907,Q9UJS0,O96005,Q00325 22 +Endoplasmic reticulum exit site 0.5155515720853134 0.7487586765534747 0.4540026705933138 1.0 0.7359436859551054 18 Q9HCU5,P53992,P04439,Q96PC5,Q5JRA6,Q9Y3A6,Q15437,O15027,Q9NR31 9 +Juxtaparanode region of axon 0.4855799969528628 0.6961008888819684 0.4863656499077118 1.0 0.7690764252074241 4 Q14168 1 +Microtubule 0.302335219248113 0.6880601551382562 0.4914149006276069 1.0 0.7728234697835634 105 P07437,Q9BVA1,Q9Y5M8,Q9UQB8,O94927,Q9BUF5,P68371,Q96DB5 8 +Dynactin complex 0.4855559883916588 0.6857710316413781 0.4928575063498002 1.0 0.7728234697835634 5 O75935 1 +Gap junction 0.4829059829059858 0.684093337449073 0.4939162287331824 1.0 0.7728234697835634 4 Q69YQ0,Q16643,Q99797 3 +Sperm midpiece 0.4840672662737678 0.6790675246873789 0.4970950781932104 1.0 0.7753199234549946 5 Q15388 1 +Specific granule membrane 0.4886137501088392 0.6524100700261978 0.5141366698509922 1.0 0.7961112794405502 11 Q07065,O00264,P30519 3 +Sperm connecting piece 0.4690391459074748 0.6440499243307835 0.5195430607245295 1.0 0.802451625905293 2 P47756 1 +Transport vesicle 0.3007686761252139 0.6244235994351914 0.5323494305620073 1.0 0.8105636049053458 85 O76024,P01889,P20020,P10321,Q9Y678,P53992,O00429,Q9BT78,O00461,Q96A57,P61421,O15260,P49755,P04439,Q92572,Q13190,Q9UKR5,O43760,P51809,Q15363,Q9BVK6,O15027,P55735,Q9Y3B3 24 +Early endosome 0.3194540580152902 0.6241536187601768 0.5325267035579255 1.0 0.8105636049053458 82 Q02750,Q9BZF3,P04083,Q9BUN8,P31751,P42858,Q9UIQ6,Q96L92,P40818,Q96J02,Q5VW38,P01889,Q9Y5X3,P10321 14 +Hops complex 0.4613741545033853 0.5995597781082861 0.548799659770602 1.0 0.8245990460519085 3 Q9H269,Q9H267 2 +Postsynaptic specialization membrane 0.4646223255148221 0.56579163640361 0.5715354326408684 1.0 0.8453146074370124 8 Q99720 1 +Perinucleolar compartment 0.4514061943752276 0.5565574524614292 0.5778298305852503 1.0 0.8502778175891631 3 Q9H2J4,P58107 2 +Origin recognition complex 0.4595464790550623 0.5517715475417618 0.5811048832915433 1.0 0.8502778175891631 7 Q9UFC0,Q9Y619 2 +Caspase complex 0.4551106933617091 0.551313155722426 0.5814190216363886 1.0 0.8502778175891631 5 Q92643,O43292 2 +Ciliary tip 0.4590607846437107 0.5496532074587807 0.5825572569996131 1.0 0.8505526019814906 7 Q7Z4L5 1 +Peptidase complex 0.4208348359713605 0.5037269208118426 0.6144532878965177 1.0 0.8855647224917605 57 P67812,P49721,P60900,P61289,P28074,Q15005,P28072,P04792,Q99436,O43396,O43292 11 +Sarcoplasm 0.4628166412561724 0.4961826231187703 0.619765569837812 1.0 0.8875805176332804 18 Q13555,O43852,P16615,P62942 4 +Gtpase complex 0.4383903133903126 0.4908270309399808 0.6235487899110763 1.0 0.8886563168318683 4 P04899,P63218,Q14344 3 +Gamma tubulin complex 0.4295373665480439 0.476024512947478 0.6340569143459334 1.0 0.8964943733643134 2 Q9BSJ2 1 +Equatorial microtubule organizing center 0.4295373665480439 0.476024512947478 0.6340569143459334 1.0 0.8964943733643134 2 Q9BSJ2 1 +Nucleotide activated protein kinase complex 0.433404558404557 0.4701501248288203 0.6382477645677738 1.0 0.8995775579341063 4 Q13131,P10644,P13861 3 +Iron sulfur cluster assembly complex 0.427554289782839 0.4569149055117011 0.6477322099358096 1.0 0.9072305600822372 3 O76003,Q86SX6 2 +Collagen containing extracellular matrix 0.4577545051871876 0.4529681214295674 0.6505716967402708 1.0 0.9097838571602224 25 P04083,P04080,O14936,Q32P28,P84157 5 +Endoplasmic reticulum quality control compartment 0.4301325981258699 0.4462307087054375 0.6554306027111629 1.0 0.915148813457864 5 Q9BUN8 1 +Transport vesicle membrane 0.4451601007491948 0.4317208793696048 0.6659442903892168 1.0 0.92129720550864 41 P49755,Q15363,P53992,Q13190,O15027,O43760,O76024,P55735,Q9Y3B3,P01889,P20020,P51809,P10321 13 +Cul4b ring e3 ubiquitin ligase complex 0.418149466192173 0.4300833664254048 0.667134999272456 1.0 0.9214287412790866 2 Q16531 1 +Golgi associated vesicle membrane 0.4448109533277816 0.4197729159425474 0.6746513522657307 1.0 0.9286351092331292 17 Q15363,Q9Y3B3,Q9Y287,Q8N511 4 +Microbody lumen 0.4448818871044805 0.4152250340850247 0.6779771741854299 1.0 0.930658851067423 18 O15254,Q15067,O00116,O75874 4 +Anchored component of membrane 0.4298428728966411 0.4091608441084724 0.6824216273657233 1.0 0.932469246553164 9 Q9ULX3,P36551 2 +Anaphase promoting complex 0.4260812966347088 0.3858539338575876 0.6996048490082154 1.0 0.9429914756963144 10 Q96DE5,Q9UJX6,Q9UJX4 3 +Emc complex 0.4066295162048866 0.3635176065204198 0.7162182630911704 1.0 0.9563797136655484 4 Q9NPA0 1 +Annulate lamellae 0.4064837905236859 0.3525774819273133 0.72440522160845 1.0 0.9563797136655484 5 P63241,P49792,Q8TD16,Q9Y5L0 4 +Brush border membrane 0.4098206111052893 0.3463138242793532 0.7291068804116883 1.0 0.9563797136655484 7 Q14728 1 +Nuclear outer membrane 0.4122421151844226 0.3387095714761207 0.7348285294612233 1.0 0.9563797136655484 9 Q99720 1 +Synaptic vesicle membrane 0.4198078307394107 0.3317717381340094 0.7400616263705564 1.0 0.9563797136655484 14 O00429,O76024,P20020,O43760 4 +Secretory granule membrane 0.3820784600638673 0.3213701778101741 0.7479298801202132 1.0 0.9563797136655484 61 Q15363,P10321,O00264,Q9NZJ7,P42785,Q93050,Q8NF37,Q4KMQ2,Q99829,P01889,O15260,Q07065,P51809,P30519 14 +Smooth endoplasmic reticulum 0.4074249341528138 0.3201097847884644 0.7488851084431087 1.0 0.9563797136655484 9 Q13217,O00264 2 +Platelet alpha granule lumen 0.4073749464012584 0.319918417788458 0.7490301756576925 1.0 0.9563797136655484 9 Q6UXV4,Q9NUQ9,Q8NBX0 3 +Polymeric cytoskeletal fiber 0.2717091077395056 0.3194796370547493 0.7493628302617878 1.0 0.9563797136655484 144 P07437,Q9BVA1,P04083,Q9Y5M8,Q9UQB8,O94927,Q9BUF5,P68371,Q96DB5,P08670 10 +Platelet alpha granule 0.4102258233298402 0.3005427548316394 0.763763189186538 1.0 0.9604539939414348 13 Q6UXV4,Q9NUQ9,Q8NBX0,P51809 4 +Phagophore assembly site membrane 0.3822064056939573 0.2949476466821552 0.7680338732967165 1.0 0.9613850581826032 2 Q7Z3C6 1 +Nuclear exosome rnase complex 0.3968788910490981 0.2724395834879505 0.785284040098492 1.0 0.9764496724726108 10 Q96B26,Q9NQT4 2 +Intrinsic component of mitochondrial outer membrane 0.3968587110120725 0.2723653470370968 0.7853411148807017 1.0 0.9764496724726108 10 Q15388,Q8TB36,O96008 3 +Mitotic spindle pole 0.4016756591571946 0.267791590057847 0.7888597445418366 1.0 0.9765626681848916 13 Q96DB5 1 +Cytoplasmic exosome rnase complex 0.397722016213135 0.2677548131974365 0.7888880548577393 1.0 0.9765626681848916 11 Q96B26,Q9NQT4 2 +Cyclin dependent protein kinase holoenzyme complex 0.3953156815384643 0.2589095550844633 0.7957050256160907 1.0 0.9822841350708982 11 O95067,P11802 2 +Microbody membrane 0.4100669583998821 0.2497068344400846 0.8028140724891846 1.0 0.9824347118894546 22 Q9BY49,Q15067,O00116,P51648,Q8TB36,P40855 6 +Nucleoid 0.4139160416069389 0.2440050063428456 0.8072269425923075 1.0 0.9824347118894546 32 P21796 1 +Mhc class i peptide loading complex 0.3620505517977925 0.2168870180742312 0.8282963948887474 1.0 0.9824347118894546 3 P30101,P04439 2 +Azurophil granule membrane 0.4000070910472493 0.2143464622495033 0.8302768882525962 1.0 0.9824347118894546 21 Q9NZJ7,P42785,Q8NF37,Q99829,O15260,Q07065 6 +Cop9 signalosome 0.3794779907176073 0.2108228876748098 0.8330254781343971 1.0 0.982454670276805 10 Q92905,Q9BT78,Q9H9Q2,Q99627,Q7L5N1 5 +Lateral plasma membrane 0.391723782643879 0.1933466494098064 0.8466874945699989 1.0 0.985911785018017 19 P04083,P36404,Q5T2T1,P53985 4 +Endoplasmic reticulum lumen 0.3823434122583125 0.1907445330578102 0.8487257468527978 1.0 0.985911785018017 53 Q96AY3,P27824,O43852,Q6P179,Q8TED1,Q13217,O95881,Q9UBS4,O76024,O75718,Q8IXB1,Q32P28,Q15293,Q9NZ08,Q14257,P13674,Q07065 17 +Mcm complex 0.3630197521286817 0.1905725871018656 0.8488604688696013 1.0 0.985911785018017 6 Q14566 1 +Lewy body 0.3517265930936332 0.1849588366300694 0.8532613220587228 1.0 0.9866523039309522 3 Q9Y4X5,Q13501 2 +Endopeptidase complex 0.383921594588959 0.1782536497624169 0.8585237779027182 1.0 0.9867871439729732 51 P49721,P60900,P61289,P28074,P28072,P04792,Q99436,O43292 8 +Pericentriolar material 0.345551601423495 0.176616041255908 0.8598099930697589 1.0 0.9867871439729732 2 Q15154 1 +Gemini of coiled bodies 0.3539322651604744 0.1721737533248487 0.8633009315428357 1.0 0.9867871439729732 5 O75312,Q16637 2 +Immunological synapse 0.3699135207007598 0.1638348454721226 0.8698611595813761 1.0 0.987976824651436 12 Q96L92,P17931,P20020 3 +Proteasome complex 0.3849708194417594 0.1453362648944251 0.8844453834362289 1.0 0.998777719843394 46 P49721,P60900,P61289,P28074,P28072,P04792,Q99436 7 +Intrinsic component of synaptic vesicle membrane 0.3557903509070312 0.1432832408491247 0.8860664911236367 1.0 0.998777719843394 9 O76024,P20020 2 +Intercellular bridge 0.373528378021346 0.1355013092111517 0.8922155292036811 1.0 1.0 18 Q13432,P21266,Q53EZ4,Q9UJX6 4 +Vacuole 0.2649028141297641 0.1329042661174003 0.8942690929639499 1.0 1.0 192 P50995,P50851,Q9NZJ7,P42785,O14964,Q9NX40,Q8N511,Q9UIQ6,P61160,O15118,Q9UHG3,Q07065,Q9Y487,Q9NXN4,Q8NCC3,Q93050,Q8NF37,Q9H7Z7,P68371,Q96CS3,P38435,O15260,P07437,P08236,O95772,P42858,Q5BJF2,Q99829,Q8NHS3,P54802,P46976,P51809,P53396,P42892,Q13217,P55735,Q15165,Q96GC9,Q9Y679,Q9Y2T2,Q01650 41 +Centrosome 0.2596198802073759 0.1273497328967257 0.8986635995444794 1.0 1.0 144 P50402,P36404,P48643,O95067,Q9Y6A5,O95684,Q86UY6,Q8TEY7,P28074,O94927,Q9BW83,Q13432,Q14155,O43292,P53985,Q9NQR4,Q96JB5,Q8N1F7,O75935,O75934,Q6DKK2 21 +Ribonucleoprotein granule 0.2580029198262777 0.1230928476867775 0.902033574928358 1.0 1.0 99 P60900,Q08J23,P51991,Q07065,P61978,P31483,Q14011,Q9BWF3,Q99729,Q5PRF9,P07437,P51116,P42694,Q01085,P19474,P51114,Q16637,Q6PKG0,P67809,Q14671,Q71RC2,Q9Y4Z0 22 +Nuclear ubiquitin ligase complex 0.3599956217830591 0.1117052768470444 0.9110570952015448 1.0 1.0 15 Q9NXR7,Q96DE5,Q9UJX6,Q9UJX4 4 +Specific granule 0.3795813531838091 0.1104669719231018 0.9120390421150466 1.0 1.0 28 O00264,Q9NQR4,Q7L576,Q07065,P30519 5 +Elongator holoenzyme complex 0.3279914529914541 0.1098131509707412 0.9125575611580076 1.0 1.0 4 Q9H9T3,Q6IA86,Q96EB1 3 +Spectrin 0.3276353276353246 0.1089156496842488 0.9132693938366896 1.0 1.0 4 Q13813,Q01082,P05771 3 +Dna replication preinitiation complex 0.3454675231977224 0.1058559808204449 0.9156966199806448 1.0 1.0 10 Q9Y248,Q9BRT9,P49736,P33991,Q9BRX5,Q9UBD5,Q14566,P33992,P33993 9 +Outer kinetochore 0.3247863247863249 0.1018268149884203 0.918894140990707 1.0 1.0 4 P53350,P49454,O60566 3 +Plasma membrane signaling receptor complex 0.3273241970370103 0.0903780799665004 0.9279867750495784 1.0 1.0 6 Q9NR28 1 +Cytoplasmic side of endoplasmic reticulum membrane 0.3246650369072306 0.0839174447475087 0.9331220695803528 1.0 1.0 6 Q8TCT9 1 +Nbaf complex 0.321568627450976 0.0686274308300827 0.9452861836915188 1.0 1.0 7 Q96GM5,Q12824,O14497,P51532,Q92922,Q969G3 6 +Golgi stack 0.3593050091936904 0.0629149288104616 0.949834246924492 1.0 1.0 23 Q15363,P04439,Q10472,Q10713,Q14789,O00461,Q14746 7 +Npbaf complex 0.3216833095577744 0.0611244058880017 0.9512601324004252 1.0 1.0 8 Q96GM5,Q12824,O14497,P51532,Q92922,Q969G3,O96019 7 +Microbody 0.3641133211850836 0.0560300762911729 0.955317847373061 1.0 1.0 48 Q9BY49,Q15067,P51648,O00116,O75874,P48735,O15254,Q709F0,P40855,P08670,Q8N4Q0 11 +Chromatin silencing complex 0.3114754098360592 0.0540167429462238 0.9569218247740968 1.0 1.0 6 Q8IXJ6,Q13185,O43159,Q15022,Q96EB6 5 +Swi snf complex 0.3217980734926873 0.0537950108503835 0.95709848453028 1.0 1.0 9 Q96GM5,Q12824,O14497,P51532,Q92922,Q969G3,Q86U86,O96019 8 +Neuron spine 0.3628443200347208 0.0525118615681967 0.958120844210976 1.0 1.0 28 P51116,Q9UQB8,Q7L576,Q14168,P51114,P40818,P20020 7 +Perinuclear region of cytoplasm 0.2577242491166547 0.0491582723865937 0.9607931648490012 1.0 1.0 169 Q9Y217,Q9UIQ6,Q7L7X3,Q8NEW0,Q07065,Q9Y487,O95684,Q9BZF3,Q8TEY7,Q10472,Q93050,Q9H7Z7,O95831,P42858,P51114,Q86UE4,O75935,O15027,P09601,Q7L576 20 +Specific granule lumen 0.328767541687944 0.0481292462066127 0.9616132381054074 1.0 1.0 12 Q9NQR4 1 +External encapsulating structure 0.3607236175869423 0.0387378509185045 0.9690993953765064 1.0 1.0 30 P04083,P04080,O14936,Q32P28,P84157 5 +Insulin responsive compartment 0.287646849412608 0.0324256679095759 0.9741325932157644 1.0 1.0 3 P51153,P20338 2 +Early endosome membrane 0.3617212857438278 0.0270334510655756 0.9784330536824828 1.0 1.0 41 Q9BZF3,P04083,Q96L92,Q96J02,P01889,P10321 6 +Golgi associated vesicle 0.3448916556730546 0.0020137495319424 0.9983932614250768 1.0 1.0 27 Q9Y678,P49755,Q9BVK6,Q15363,Q9Y287,P42356,Q8N511,Q9Y3B3 8 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..74f7ccbe3bdda7a85ee965e4a01def78dca20e3a --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "L type voltage gated calcium channel complex", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Muscle myosin complex", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Picln sm protein complex", "Pigment granule", "Pinosome", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Smad protein complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAMP", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRD1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "C12orf43", "C19orf70", "C1QBP", "C1orf35", "C2orf49", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CAST", "CBFB", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC58", "CCDC8", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CENPF", "CENPI", "CEP170", "CEP44", "CEP55", "CEPT1", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP2L", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CRKL", "CRNKL1", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX35", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DPM1", "DPYSL2", "DR1", "DRG1", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "ELAC2", "ELAVL1", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAHD1", "FAM162A", "FAM208A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGB1", "GOLIM4", "GOLM1", "GORASP2", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSR", "GSTK1", "GSTM2", "GSTM3", "GTF2F1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS5", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HP1BP3", "HPF1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "ISOC1", "IST1", "ITCH", "ITGB1", "ITM2B", "ITPK1", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANBA", "MANF", "MAP1B", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL13", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD8", "MGAT1", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMADHC", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NF1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALLD", "PARK7", "PARN", "PARP1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDZD11", "PECR", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHF6", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA2", "PPAN", "PPIB", "PPID", "PPIF", "PPIH", "PPIL1", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRSS3", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPN1", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RMDN1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT2", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STMN1", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF2", "TAF5", "TAF6L", "TAMM41", "TAOK1", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TKT", "TLN1", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT112", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC37", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "UBA1", "UBA2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGGT1", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WFS1", "WIZ", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYND8", "ZNF207", "ZNF326", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABHD10", "ABHD12", "ACAD11", "ACAT2", "ACLY", "ACOX1", "ACOX3", "ACP6", "ACTL6A", "ACTR2", "ADPGK", "AFG3L2", "AGK", "AGPAT1", "AGPS", "AGTRAP", "AHCYL1", "AIFM1", "AKAP8", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALG1", "ALG5", "ANAPC16", "ANAPC2", "ANAPC5", "ANK3", "ANKLE2", "ANKRD17", "ANO6", "ANXA1", "ANXA11", "ANXA7", "AP3M1", "AP3S1", "APOL2", "APOOL", "ARHGEF7", "ARID1A", "ARIH1", "ARL2", "ARL6IP1", "ATAD3A", "ATAD3B", "ATG9A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATPAF1", "AUP1", "BABAM2", "BAG6", "BAIAP2", "BCAS2", "BCL2L13", "BICD2", "BRI3BP", "BSG", "BUB1B", "C19orf70", "CALU", "CAMK2G", "CANX", "CAPZB", "CASK", "CBX3", "CCDC134", "CCDC47", "CCNB2", "CCT5", "CDK4", "CDK5RAP3", "CDKAL1", "CENPF", "CEP55", "CEPT1", "CERS2", "CHCHD3", "CIRBP", "CKAP4", "CLPP", "CLPTM1", "COA3", "COA7", "COG2", "COPG1", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COX15", "COX2", "COX4I1", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPT2", "CRTAP", "CSTB", "CYB5B", "CYFIP1", "CYP51A1", "DBN1", "DCTN3", "DDB1", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHX33", "DIABLO", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC3", "DNM1L", "EARS2", "ECE1", "EI24", "EIF5A", "ELOC", "ELP2", "ELP3", "ELP4", "EMC7", "EMD", "EPHX1", "EPPK1", "ERAP1", "ERAP2", "ERC1", "ERG28", "ERGIC2", "ERGIC3", "EXOSC5", "EXOSC8", "FAF2", "FAM162A", "FAM49B", "FAM8A1", "FAR1", "FASN", "FDFT1", "FGFR1OP", "FKBP10", "FKBP1A", "FOXRED1", "FXR1", "FXR2", "GAK", "GALNT1", "GCDH", "GDAP1", "GDAP2", "GGCX", "GHITM", "GINS2", "GINS3", "GINS4", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GNA13", "GNAI2", "GNG5", "GNPAT", "GOLGB1", "GOLIM4", "GPAA1", "GPR107", "GPR108", "GPX8", "GSTM3", "GUSB", "GYG1", "HACD3", "HAUS5", "HELZ", "HGS", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPA3", "HNRNPAB", "HNRNPK", "HNRNPR", "HS2ST1", "HSDL1", "HSPA13", "HSPB1", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IFT27", "IKBIP", "ITCH", "ITM2B", "JAGN1", "KDSR", "KHDRBS1", "KIAA0319L", "KIF5B", "LANCL1", "LARP1", "LARP4", "LGALS3", "LLGL1", "LMAN2", "LNPEP", "LPCAT1", "LPGAT1", "LRBA", "LRRC59", "LRWD1", "LSM4", "LSS", "MAP2K1", "MBOAT7", "MCL1", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "METTL13", "MFSD10", "MFSD8", "MGME1", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMADHC", "MOV10", "MPP2", "MPP7", "MPV17L2", "MRPS9", "MSMO1", "MSTO1", "MTCH1", "MTCH2", "MTDH", "MTMR6", "MTX1", "MTX2", "MXRA7", "MYCBP", "MYH10", "MYL6B", "NAA15", "NAA40", "NAGLU", "ND1", "NDC1", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NEDD4L", "NENF", "NIT2", "NLN", "NNT", "NOB1", "NPC1", "NSUN2", "NUCB2", "NUP160", "NUP37", "NUP85", "NUP93", "OCIAD1", "OPA1", "ORC3", "OSBPL6", "OSBPL8", "OXA1L", "P3H1", "P3H4", "P4HA1", "PAIP1", "PBRM1", "PCM1", "PCYOX1", "PDCL3", "PDE6D", "PDIA3", "PDK3", "PECR", "PEX19", "PFDN5", "PFDN6", "PGRMC1", "PGRMC2", "PI4KA", "PIGK", "PITRM1", "PLA2G15", "PLD6", "PLK1", "PMPCA", "POLE", "POLE4", "PON2", "POR", "PRCP", "PREB", "PRKAA1", "PRKAR1A", "PRKAR2A", "PRKCB", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PSME3", "PSMG1", "PTGES2", "PTPN1", "PUM1", "QSOX2", "RAB13", "RAB3GAP1", "RAB4A", "RANBP2", "RBM4", "RCN1", "RCN2", "RDH13", "RER1", "RMDN1", "RPN1", "RRP8", "RTN3", "RTN4", "SACM1L", "SAMD4B", "SAMM50", "SAR1A", "SCCPDH", "SCO1", "SCO2", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC23B", "SEC24C", "SEC63", "SET", "SFXN4", "SGPL1", "SIGMAR1", "SIRT1", "SIRT2", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A6", "SLC30A7", "SLC35A4", "SLC35B2", "SLC7A1", "SLC7A5", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCD1", "SMARCE1", "SMN1*", "SNX27", "SNX5", "SPCS2", "SPECC1L", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQSTM1", "SRPRB", "SSR1", "STARD3NL", "STT3A", "STX18", "STX5", "SURF4", "SUZ12", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TAOK1", "TBL2", "TECR", "TELO2", "THOP1", "TIA1", "TIAL1", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TM9SF2", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM199", "TMEM230", "TMEM259", "TMEM33", "TMEM97", "TMPO", "TMX1", "TMX2", "TMX4", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOR1AIP2", "TPM1", "TPM4", "TRA2B", "TRAM1", "TRIM21", "TRMU", "TSPAN6", "TSPO", "TTC19", "TTC21B", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TXNDC12", "TXNL1", "UNC119", "UQCR10", "UQCRFS1", "UQCRQ", "USMG5", "USP33", "USP8", "VAMP7", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS33B", "WFS1", "YBX1", "YIF1A", "ZADH2", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_gomf/advanced/idx2term.json b/msigdb_gomf/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..86efc3e5850863663bcf3ba17c86cc6775211a79 --- /dev/null +++ b/msigdb_gomf/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Ion transmembrane transporter activity", "2": "Oxidoreductase activity", "3": "Cation transmembrane transporter activity", "4": "Fad binding", "5": "Lipid binding", "6": "Inorganic molecular entity transmembrane transporter activity", "7": "Monooxygenase activity", "8": "Active transmembrane transporter activity", "9": "Protein transmembrane transporter activity"} \ No newline at end of file diff --git a/msigdb_gomf/advanced/plot_0.png b/msigdb_gomf/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b53ecc54d0b77c0f84dfd17c55f671e94b06aefd --- /dev/null +++ b/msigdb_gomf/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e300d688653e787c3ed455f084439462ba3f0e978f62cb2b1b962b6ab37b695 +size 216050 diff --git a/msigdb_gomf/advanced/plot_1.png b/msigdb_gomf/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d996ea9b775c5aa478b8ee1cdabf0f9a2d99af95 --- /dev/null +++ b/msigdb_gomf/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5d960a1ae229e2a9f56a72d2ac6b04eb95b4a0eebcc3d269840efb14d470949 +size 212375 diff --git a/msigdb_gomf/advanced/plot_2.png b/msigdb_gomf/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..71a18332c31006682f0bbfbd5f3c484ff2cbfa95 --- /dev/null +++ b/msigdb_gomf/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2775b858753751dad75a6f1dfa7ca4762e877b7c9a1f120f4b7f61e140c3f1a2 +size 218777 diff --git a/msigdb_gomf/advanced/plot_3.png b/msigdb_gomf/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..23ea34df5512b118892f37d127398fc78aaf7079 --- /dev/null +++ b/msigdb_gomf/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27d01a638dfef3e808bcea5331227b4d885af7fe34a0d00574aca215623cc9d9 +size 210452 diff --git a/msigdb_gomf/advanced/plot_4.png b/msigdb_gomf/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..e4071b84ff2b68f41a6c641fbe46b9c0864ceb38 --- /dev/null +++ b/msigdb_gomf/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b088cc0978d15018a5b498c212a19c9f49f0dc369c0d32257f35f92a059eb3e6 +size 192127 diff --git a/msigdb_gomf/advanced/plot_5.png b/msigdb_gomf/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..1df940b9d696a97f20d2cb91faa6233c9bb57b68 --- /dev/null +++ b/msigdb_gomf/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52abefc5c3008120c5b82ed8451357b4700a76c41887411458fd5c72ede58698 +size 218391 diff --git a/msigdb_gomf/advanced/plot_6.png b/msigdb_gomf/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..cf53b7a3d38c315ccbc6fcf3d4293fc95a6de297 --- /dev/null +++ b/msigdb_gomf/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d738cffd9bfd0705cbb8ffcfdd274ade30046499b219a7a601bdfce4bc30a041 +size 210157 diff --git a/msigdb_gomf/advanced/plot_7.png b/msigdb_gomf/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..ceb97e144abd131efcc52f79a2765dfbd0af24f7 --- /dev/null +++ b/msigdb_gomf/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:df5c5b57f4a54a67c6064cbe185a797893e0c605eee8b88befb19fe72d4d3848 +size 194126 diff --git a/msigdb_gomf/advanced/plot_8.png b/msigdb_gomf/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..fc461ee0713579dc450b41f5955597488599ec68 --- /dev/null +++ b/msigdb_gomf/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f21a67b8bd5c4a70b588e4bc42a8a8388b159543a4d2468c86e48efb8c74d6f +size 212624 diff --git a/msigdb_gomf/advanced/plot_9.png b/msigdb_gomf/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..bb5979e5d67a427f5ce5fb68859bee407777be18 --- /dev/null +++ b/msigdb_gomf/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:311df0821a60f4f0239977fda0d35bb9fc85a00216087597df55694e66266043 +size 196110 diff --git a/msigdb_gomf/basic/idx2term.json b/msigdb_gomf/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..b6d517af287f2790db06b93310de0a18eeeb458c --- /dev/null +++ b/msigdb_gomf/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Ion transmembrane transporter activity", "2": "Oxidoreductase activity", "3": "Cation transmembrane transporter activity", "4": "Fad binding", "5": "Lipid binding", "6": "Inorganic molecular entity transmembrane transporter activity", "7": "Monooxygenase activity", "8": "Active transmembrane transporter activity", "9": "Protein transmembrane transporter activity", "10": "Protein transporter activity", "11": "Macromolecule transmembrane transporter activity", "12": "Nucleobase containing compound transmembrane transporter activity", "13": "Transition metal ion binding", "14": "O acyltransferase activity", "15": "Peptidase activity", "16": "Tetrapyrrole binding", "17": "Primary active transmembrane transporter activity", "18": "Organic acid transmembrane transporter activity", "19": "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "20": "Oxidoreduction driven active transmembrane transporter activity", "21": "Atpase coupled cation transmembrane transporter activity", "22": "Anion transmembrane transporter activity", "23": "Cholesterol binding", "24": "Proton transmembrane transporter activity", "25": "Misfolded protein binding", "26": "Metalloendopeptidase activity", "27": "Lamin binding", "28": "Atpase coupled transmembrane transporter activity", "29": "Steroid binding", "30": "Secondary active transmembrane transporter activity", "31": "Active ion transmembrane transporter activity", "32": "Organic anion transmembrane transporter activity", "33": "Zinc ion binding", "34": "Alcohol binding", "35": "Metalloaminopeptidase activity", "36": "Protein methyltransferase activity", "37": "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "38": "Passive transmembrane transporter activity", "39": "Sterol binding", "40": "Endopeptidase activity", "41": "Flavin adenine dinucleotide binding", "42": "Aminopeptidase activity", "43": "Oxidoreductase activity acting on the ch ch group of donors", "44": "Nf kappab binding", "45": "Peptide binding", "46": "Proton transporting atp synthase activity rotational mechanism", "47": "Proton channel activity", "48": "Metalloexopeptidase activity", "49": "Electron transfer activity"} \ No newline at end of file diff --git a/msigdb_gomf/basic/plot_0.png b/msigdb_gomf/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..a6a3aa07e8c12fcb0252cd03fe3c3feef78cf3ec --- /dev/null +++ b/msigdb_gomf/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b243a2c42e988ff9e962e085a99394a563b358cb2bdf2a769e9adf36c0cdb5d1 +size 138517 diff --git a/msigdb_gomf/basic/plot_1.png b/msigdb_gomf/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b619c03a7042c1a792f66d8beae85ecdac7d4fa8 --- /dev/null +++ b/msigdb_gomf/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72493212e6f78e914268fa21848501b4c5b46be6ea8cac4d07767d50ca0fc15a +size 146305 diff --git a/msigdb_gomf/basic/plot_10.png b/msigdb_gomf/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..c1440bffee12daa51a5e77b45be6c6dbc69cf469 --- /dev/null +++ b/msigdb_gomf/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b4255d7476b670ea288679e9550a5621aae223e8e454e721010c67d1d30993e +size 136745 diff --git a/msigdb_gomf/basic/plot_11.png b/msigdb_gomf/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..93036a3ed04e6c29550d90f9a55e0083091e7058 --- /dev/null +++ b/msigdb_gomf/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ec626d74406bce5d96cfd13497ce168a5ace528ae9f0a9bccb3507fe2fca9fe +size 141900 diff --git a/msigdb_gomf/basic/plot_12.png b/msigdb_gomf/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..d4984b9a3a16b23df04ee672f96c8ba4fac24c73 --- /dev/null +++ b/msigdb_gomf/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:084632c5cbfaf7913513a9ea5fe3756c81dc46f1614dd01378d4b141431303fa +size 141595 diff --git a/msigdb_gomf/basic/plot_13.png b/msigdb_gomf/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..7f5a8f1bba9ce3d681fa2ae232d5a93541262356 --- /dev/null +++ b/msigdb_gomf/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d156febdab18949fed036935248376e31bb01b0741eef4781592e1532e57bc83 +size 140017 diff --git a/msigdb_gomf/basic/plot_14.png b/msigdb_gomf/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..03a7921f8e62030e888dd9738852972f443e9f04 --- /dev/null +++ b/msigdb_gomf/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b937c1bdb6b5f3dcc152f8d2d52c415ef6965c531306e1c74ea266f423b4d6d +size 136393 diff --git a/msigdb_gomf/basic/plot_15.png b/msigdb_gomf/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..4d52be5865728be3970473368da5c602e3278c04 --- /dev/null +++ b/msigdb_gomf/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bea1e84b8f8f9180660556eac420213b4226165b7620719b9dd2d25e140409f9 +size 132745 diff --git a/msigdb_gomf/basic/plot_16.png b/msigdb_gomf/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..e8c23fc792310fa52e1605a4093989e07747a7d7 --- /dev/null +++ b/msigdb_gomf/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67ec846621402e32c876545e89f0ba0feaeede4dd89620029f9cfbfbfe176938 +size 130130 diff --git a/msigdb_gomf/basic/plot_17.png b/msigdb_gomf/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..2ad7d71defd6def1d757a8cc93214280e7738541 --- /dev/null +++ b/msigdb_gomf/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a94af374b36476a4c524d8b1055eefbc831cdc1e4a8ea275a15b44ebe7e4c37f +size 140701 diff --git a/msigdb_gomf/basic/plot_18.png b/msigdb_gomf/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..bcfed868fa33ff5ba7a6934693182f072dc11d36 --- /dev/null +++ b/msigdb_gomf/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94f1609d80990981d055793223265aad0f2201fbe305326279d693c2f6922d4a +size 129147 diff --git a/msigdb_gomf/basic/plot_19.png b/msigdb_gomf/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..9b6ed13156f82fab9aa8358248b0095a9554da33 --- /dev/null +++ b/msigdb_gomf/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a6e68c2f511318b741c018f3f3bc4889a8df99468de32f3cee09e712d0a15e7 +size 139211 diff --git a/msigdb_gomf/basic/plot_2.png b/msigdb_gomf/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e3adf4ae64954c688e947a183c3281150b2ec383 --- /dev/null +++ b/msigdb_gomf/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8d46044c5b6f7364ec45d31fb5de1dc79af07d95c7f54811c88dd8c9f01e204 +size 146034 diff --git a/msigdb_gomf/basic/plot_20.png b/msigdb_gomf/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..d2e217c7ef315a77b1246c9ec141c179feddfa22 --- /dev/null +++ b/msigdb_gomf/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6ed94ab84acb6aed5e78e1aeac3424e590e1f55dd7fc17a1b6faa69a68a66ea +size 140181 diff --git a/msigdb_gomf/basic/plot_21.png b/msigdb_gomf/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..25afc31ea3aa0f8c0aa97fc6058489cc8806f3ff --- /dev/null +++ b/msigdb_gomf/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:621d26bac2eec86238542f2ba37e9035dfc0c12f345e179b2d2a476cd3217b90 +size 137944 diff --git a/msigdb_gomf/basic/plot_22.png b/msigdb_gomf/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..60c545d0873c87f6ecac020c9ef820227dfd922e --- /dev/null +++ b/msigdb_gomf/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc91f182a9b9789e51fec9d9615ed673aaa486c1b8af5e09516ec3a6b62a6a8a +size 138106 diff --git a/msigdb_gomf/basic/plot_23.png b/msigdb_gomf/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..865f78fb10bd4392e2511a0d0d5ad17640e57f01 --- /dev/null +++ b/msigdb_gomf/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f834b6a9247e5b6364579da0d904647e9235ad588e13228c7d866256990ebc6e +size 121660 diff --git a/msigdb_gomf/basic/plot_24.png b/msigdb_gomf/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..f044be0a818a498a9fc6473ec7e12c82ebeb4349 --- /dev/null +++ b/msigdb_gomf/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:373e648e28c509fec6c01ea9cd9894b099a1311160bfe80e8875bd9ad37bd71b +size 140441 diff --git a/msigdb_gomf/basic/plot_25.png b/msigdb_gomf/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..fad06e32c59cf1035ab6076f47653318a8aebccf --- /dev/null +++ b/msigdb_gomf/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bf5b1e9d28787ca29e0a104e0a914d0a892f260be9d0083afeac04899555130e +size 134600 diff --git a/msigdb_gomf/basic/plot_26.png b/msigdb_gomf/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..74dce8a4cfd3c444eb36a27996f005549a5d204f --- /dev/null +++ b/msigdb_gomf/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8808b1a89edf8944dda4378a508d4aa91b4781cea20e7f258b2b61244a97a7fa +size 138361 diff --git a/msigdb_gomf/basic/plot_27.png b/msigdb_gomf/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..67f142760f57c67c8f1487c948b4c95ae9d00076 --- /dev/null +++ b/msigdb_gomf/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a17ccc59233529a6e5750c3efa3599429d75306690bc6ffd8083b1fe2ba5f89 +size 125549 diff --git a/msigdb_gomf/basic/plot_28.png b/msigdb_gomf/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..70c7d419ba98bb3bae53b6b055f87dc2ac65ea43 --- /dev/null +++ b/msigdb_gomf/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b11d3440cbb176b12c9855751b9e6a99b673cd9de976559e277f8bf0ec2b720 +size 141803 diff --git a/msigdb_gomf/basic/plot_29.png b/msigdb_gomf/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..88b605f498847499f188860014179ca9f18517de --- /dev/null +++ b/msigdb_gomf/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8d050d6bc7f2f7de4e9967e382f395d2fcb1029d24079d859e763566c44dd177 +size 131998 diff --git a/msigdb_gomf/basic/plot_3.png b/msigdb_gomf/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..652bdcd58429b2777b94017d92acd7059867b8c1 --- /dev/null +++ b/msigdb_gomf/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dbdce804ce2251104c8d1a9935a2d134629f83ac60f7a0c7650bf269a4a65d41 +size 141638 diff --git a/msigdb_gomf/basic/plot_30.png b/msigdb_gomf/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..1c4b33d1ba9b68d73cc8aaa95c9db344b3463cd6 --- /dev/null +++ b/msigdb_gomf/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:acfe27aa9c5048d3baf10bc9c73eaf9bbff58c822087765dc7918aaa45ac7e77 +size 142531 diff --git a/msigdb_gomf/basic/plot_31.png b/msigdb_gomf/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..6a8cc2a757981adacca0a65f50ef85f16af011e6 --- /dev/null +++ b/msigdb_gomf/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b8330bdcbb509a5e405e5d933a9de1fc8c8e1a01f3dfb8dbfa8aadca98f5fc8 +size 142717 diff --git a/msigdb_gomf/basic/plot_32.png b/msigdb_gomf/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..60acd94a1d2a172d1eb415266a1ce80d64af6408 --- /dev/null +++ b/msigdb_gomf/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:587b5cfac1e7933de22383d01ba23980bd4fb412cb9c81c5edce65094d2c3571 +size 142297 diff --git a/msigdb_gomf/basic/plot_33.png b/msigdb_gomf/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..dec93cc3ecae1186e5dd562b163730a4fcabd2b5 --- /dev/null +++ b/msigdb_gomf/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de0348185310f7ddaa017dc8d16f9e4b2a1be3caa59ac2ba11d26cb5fb129702 +size 136429 diff --git a/msigdb_gomf/basic/plot_34.png b/msigdb_gomf/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..2edc69afac30a60f9dae643a3258e8b858b2338c --- /dev/null +++ b/msigdb_gomf/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:144a192be90fde5d9509e9980f0128c7f48f3051ed410f76bc967a7f4bb57796 +size 131184 diff --git a/msigdb_gomf/basic/plot_35.png b/msigdb_gomf/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..52946446da51445dcf8247b5aa62861d45a88f0e --- /dev/null +++ b/msigdb_gomf/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8891a0bac78eede3bb385bb7b9c654dcbfa9f1c854839156f6220142d9d2166b +size 138324 diff --git a/msigdb_gomf/basic/plot_36.png b/msigdb_gomf/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..126d1126e4c8da3ea4a949b7249c1826a2b7b77a --- /dev/null +++ b/msigdb_gomf/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ef64287c5bf2218d3522585e0c46876ae34b79426b0364d142e05fc95195477 +size 140489 diff --git a/msigdb_gomf/basic/plot_37.png b/msigdb_gomf/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..27986ee5db6e2943cf4433713c0880e924c6f234 --- /dev/null +++ b/msigdb_gomf/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fbf4ca71b60a5da0a0f342d4f489124c8b86b159baf72adce7c5611e645d206 +size 146491 diff --git a/msigdb_gomf/basic/plot_38.png b/msigdb_gomf/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..ebfbc1d8e53356b54b42f64d29b054b500f4ed2e --- /dev/null +++ b/msigdb_gomf/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e4e45dcd83e90dd3b81672b2da0996d682dc29ffd38bca7adc6ab969aba20a0 +size 142766 diff --git a/msigdb_gomf/basic/plot_39.png b/msigdb_gomf/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..0df95392dee6e0768b465d7f35a04e3d13f5b696 --- /dev/null +++ b/msigdb_gomf/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7cbe08551ceb4c010dc47aee8c0eef1d1aff5b8d10c1f4e97b56e5fa5a2b8574 +size 131838 diff --git a/msigdb_gomf/basic/plot_4.png b/msigdb_gomf/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ab651b9d4ed8b09eedb7a58b00fc1902068fea1f --- /dev/null +++ b/msigdb_gomf/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0a83464f51ae3b1006cead37b9c59aaf1b33003723701874f8038eae4de7d8f7 +size 128877 diff --git a/msigdb_gomf/basic/plot_40.png b/msigdb_gomf/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..2d39c7ecb9259c25d219b1a5e4d6a53644a8cd0f --- /dev/null +++ b/msigdb_gomf/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f50f7277ef37ec134ee59cbe80f58f3229f27b83cd928fb501d84cce2e25cee8 +size 133143 diff --git a/msigdb_gomf/basic/plot_41.png b/msigdb_gomf/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..4fddcd2ae477ccc3e5ebde3ca9a80cea817e4639 --- /dev/null +++ b/msigdb_gomf/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81083ce0b21f677ac4dbda868e9601132622062d982a2180f295a468cf93986d +size 141662 diff --git a/msigdb_gomf/basic/plot_42.png b/msigdb_gomf/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..6da7a561bab7645bc3f089eab051e5bf7ff49f64 --- /dev/null +++ b/msigdb_gomf/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6df928d3a61d987f1d79a9d266db1790354b263566329acef216d1cb59cf193f +size 136930 diff --git a/msigdb_gomf/basic/plot_43.png b/msigdb_gomf/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..d74a205f67591a013eecdfa8f2dbf8bef3d4f94a --- /dev/null +++ b/msigdb_gomf/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3537026e64cce8da8f207f3b20ec9bd8131cf7f46f0a46ae8052b7d6cc81e1f1 +size 145738 diff --git a/msigdb_gomf/basic/plot_44.png b/msigdb_gomf/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..3da170634ce911b15e966f1ba4fe1841aab5f380 --- /dev/null +++ b/msigdb_gomf/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a705a4feb8cc953e5ce300e9c640d55d64b80aa2f0fc518f5f7bd7c14116c736 +size 134990 diff --git a/msigdb_gomf/basic/plot_45.png b/msigdb_gomf/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..5677a8fcc703e92cc8d7290aef691a92c8bf4642 --- /dev/null +++ b/msigdb_gomf/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aca0e0baf825e081e84cb9928255552278a92a975a8bed7a6e4e358e5f0b4b11 +size 141669 diff --git a/msigdb_gomf/basic/plot_46.png b/msigdb_gomf/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..b4cd26cd9141591be03ecdb819e28ca85fa75d74 --- /dev/null +++ b/msigdb_gomf/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2232a8a0d1677635f6bb8f026b560d1c7a26b8f1e837bfface53cb51f47ff9d2 +size 143874 diff --git a/msigdb_gomf/basic/plot_47.png b/msigdb_gomf/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..1bbe3fd362702d5812a904e3379fd2dfa1566d07 --- /dev/null +++ b/msigdb_gomf/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94abd2eab2595ab45abe9553e01063a048b9c2ccd78d01e6d92c9f647fac4061 +size 136351 diff --git a/msigdb_gomf/basic/plot_48.png b/msigdb_gomf/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..6f7e5e9ab221ad8d767bedd679258dd3c6638bf2 --- /dev/null +++ b/msigdb_gomf/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:23dc10b821d51e34d4ef87959148df1a87dc621f9a1a1673bc2e5c716e0c3543 +size 140270 diff --git a/msigdb_gomf/basic/plot_49.png b/msigdb_gomf/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..d874b61e7075f6b333a772ac080c3c61354a14db --- /dev/null +++ b/msigdb_gomf/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38bd2b380d05614949f00286820cacc568812c35cfaf493b508ff4957d85700e +size 140330 diff --git a/msigdb_gomf/basic/plot_5.png b/msigdb_gomf/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..ae24def568d2f3140579ac130562f39e56f773ac --- /dev/null +++ b/msigdb_gomf/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f15e003789b16e40f451d338443002c5c724cfb8984a937d784e1cd433b1800a +size 134746 diff --git a/msigdb_gomf/basic/plot_6.png b/msigdb_gomf/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..caad355e9fef279e5c0c24a586b1e93631704fe5 --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:628ab7e208a1387f14dd4cdd48af38cfaac4f1cb19bf7fc90f89d1b9802d84de +size 142492 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..4ff8849ab93f7d66e129f280e9d730f200a3bc1b --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47b3d3067fe9591ccd35857184d14124c42563107d2b40b380966b71307d15e3 +size 138742 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..c0593d0033c64811fbae023d5c05e4deceb1e76e --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0ef9eed4c98486421220f381446285718bd611a113e9425a0dc9349a4e3e0a4 +size 143897 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c5cb1e899cbe964d080df640f1f7ad0dc55b8527 --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c89031630f9efb6433a6141e21aca0efc665f7e41c5c58bcc5769541dd364643 +size 139489 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9aafca01c6a0b7fbf18ad164b44f3a3c5cd93e22 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:48fa38440a6089c3d4bd62db843b57b7af24caf5d04e278dafbacaa14f2608e4 +size 215850 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a13a64114676167cd236b619c22d2316a39d0455 --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,33 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter activity 61 155 5.486044779609316 4.110327444711227e-08 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 1.5073667288277727e-08 3.4547551545681746e-06 6.59952159755069e-08 2.116731900426553e-09 8.266300873318396e-12 +Ion transmembrane transporter activity 34 91 4.458498723263175 8.253568857696791e-06 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 1.4273980411660314e-05 0.000566057670652 3.552855094755929e-05 5.655627891867588e-05 9.434878857162134e-07 +Oxidoreductase activity 56 210 3.155215988085019 0.0016037932824164 52.54126213592233 227.42961165048544 0.490492706528076 0.5955656171597654 20.033606385640603 16.688970744458114 1.2909283370539455 0.4039853598071011 1.2699362241227542e-08 0.0064661593883476 3.95463018417858e-05 9.815387729765069e-09 1.7638221039862145e-12 +Cation transmembrane transporter activity 31 64 2.524470027232668 0.0115872885514376 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.0116140917770048 0.0229384919777869 0.0063945833178523 0.0038163131290227 5.353801158021762e-05 +Sphingolipid binding 2 5 2.447932752486219 0.0143678469052745 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0231783227289601 0.0031646532309382 0.0124120710913681 0.0683566835720805 0.0539281835546241 +Voltage gated anion channel activity 3 5 2.4212569621186315 0.0154669396880733 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0002545015529425 0.0009534063593398 0.0038356556834428 0.0014512760162947 0.0009118158302113 +Fad binding 6 9 2.387767812894664 0.0169510472805936 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0003504793884845 0.1155957163384056 0.0018516158363228 0.0003345965146668 0.0001788650990257 +Abc type transporter activity 0 5 2.382497587365082 0.0171956446603327 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 0.2836730084964235 0.1114021565620111 0.2127898194125335 0.4559893986318888 0.7122509845733965 +Symporter activity 2 6 2.351872859457452 0.0186791583271614 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 1.0 1.0 1.0 0.6578404755542322 0.3610395035532395 +Lipid binding 16 125 2.340869527471994 0.0192388890974604 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0064786474228849 0.1596751302288143 0.0034878607778692 0.0426982558951842 0.1459118749743994 +Sulfur compound transmembrane transporter activity 2 6 2.3308573032959634 0.0197608853222834 2.9635922330097086 6.752427184466019 1.4746434057995097 0.1672652154050841 1.7026919602194592 1.5538455059459366 1.0954441166028872 0.2266277553273111 0.0064491952639604 0.1280604643503683 0.0025491163441 0.0316151554384263 0.0498364179528963 +Inorganic molecular entity transmembrane transporter activity 28 65 2.31375921876608 0.0206809335124964 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.0049469030990045 0.0054817326666829 0.0021602927162131 0.0058252678926633 0.0016589718556063 +Oxidoreductase activity acting on a heme group of donors 3 6 2.2962109775631645 0.0216638211824025 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 1.0 1.0 1.0 1.0 0.0048822579474643 +Oxidoreductase activity acting on other nitrogenous compounds as donors 0 6 2.27965273454058 0.0226282926585144 0.9053398058252428 4.968446601941747 0.7298979816211466 0.356591048806678 1.1939453367119757 0.8074137752294054 0.9976202195593978 0.2661615032217306 0.0891072447823885 0.0325017468768143 0.0647424502180396 0.1565948204648432 0.2942334307578267 +Monooxygenase activity 5 8 2.274666427126928 0.0229259479338139 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 2.4131411533756725e-05 0.1197698958477507 0.0269433955752302 0.0004026692559945 0.0002314752232909 +Active transmembrane transporter activity 21 62 2.26033239516145 0.0238006288559571 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 0.051679739669598 0.0692226115210366 0.0124876133563347 0.0095419748981567 0.0003180568974199 +L amino acid transmembrane transporter activity 3 9 2.2598668258451866 0.0238295173837033 3.628640776699029 8.201456310679612 0.919975936290114 0.2876791162304417 2.2759730869054327 1.0290432051153906 1.15482978403653 0.2925518180165951 0.3209592115478971 1.0 0.2423974925429197 0.1532325517723639 0.0498364179528963 +Protein transmembrane transporter activity 6 11 2.2504588475959544 0.0244198330156841 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 0.0013474758590725 6.357667188483331e-05 0.0005152543640852 1.7947231953922547e-06 4.811826196161669e-07 +Anion channel activity 3 8 2.246124533891227 0.0246960322916915 4.20873786407767 11.21116504854369 1.03959259790327 0.2192420598609839 2.3076742714116403 2.0905640066649145 1.3937691950814175 0.2662450395835827 0.0058378935913216 0.0075879492488378 0.0288389511657702 0.0288428745821564 0.0446088038944012 +Protein transporter activity 6 14 2.2277412710114386 0.0258977731775493 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 0.0002996168458583 5.086318889591563e-06 8.353230020730173e-05 1.4102019694801708e-06 1.4175664763662648e-06 +Macromolecule transmembrane transporter activity 6 12 2.159131212965489 0.030839988734066 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.0021943875549203 0.0001055314719321 0.0008461128461095 5.2899810750338045e-06 2.1902966903943494e-06 +Acylglycerol o acyltransferase activity 4 6 2.1420126386425693 0.0321924650165297 2.6601941747572817 6.820388349514563 0.8174935736497821 0.2734948556707107 1.708365471336677 1.514259678343348 1.2372108727630755 0.2654117957889352 0.2443554045423122 1.0 0.1820374447866984 0.0895680133917324 0.0028145739091465 +Lysophospholipid acyltransferase activity 3 5 2.1311606044421745 0.0330759133141282 2.4733009708737863 5.805825242718447 0.4588868874829844 0.3808793592027135 1.45207109427004 1.4282738065746603 1.1906123473894044 0.3028968768080747 0.2239007401958742 1.0 0.1662183776826317 0.0752233407476578 0.0118865434534573 +Peptide antigen binding 4 6 2.1059506390524474 0.0352086402708198 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 0.1813283262685859 0.0683810764565047 0.1336663515258769 0.0491545726752397 0.0005289198821125 +Threonine type endopeptidase activity 3 8 2.103424254989008 0.0354287000581681 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 0.0073045224575045 0.0461123069087121 0.0038356556834428 0.0014512760162947 0.0009118158302113 +Threonine type peptidase activity 3 8 2.103424254989008 0.0354287000581681 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 0.0142690277877654 0.0639684350193291 0.0075668597133861 0.0040998381065295 0.003721367796782 +Organophosphate ester transmembrane transporter activity 3 8 2.075803052058074 0.03791216998495 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 0.0338146253630333 0.0987043131013681 0.0182841548675732 0.0970188007029606 0.0200033311952484 +Nucleotide transmembrane transporter activity 3 8 2.075803052058074 0.03791216998495 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 0.0310048988007753 0.0944323477659319 0.016724444992627 0.0895680133917324 0.017002584405276 +Prenyltransferase activity 2 5 2.042934472644688 0.0410589252397861 2.099514563106796 6.009708737864078 0.6003375563696288 0.3888587975741492 1.4081247453019228 2.026499903013553 1.0962032128239394 0.3008779016140248 1.0 1.0 1.0 0.0491545726752397 0.0334620993119388 +Trna methyltransferase activity 1 5 2.0292084367943515 0.0424370646173952 3.0145631067961167 8.354368932038835 0.0860527239710543 0.5964711998733863 2.1519423498517547 2.316185208946292 0.8346999218487118 0.2982134343185151 0.3476536493790907 1.0 1.0 0.1789098805923502 0.4647244871500471 +C4 dicarboxylate transmembrane transporter activity 1 5 2.010141499090057 0.0444162149432656 2.5800970873786406 5.762135922330097 0.7175594553016044 0.3314419534241876 1.791536735339018 0.4257754786552994 1.1176795047305017 0.2969876515759702 0.1364388664089949 1.0 0.0998570540504815 0.2348471946143729 0.0968157430558884 +Protein phosphatase 2a binding 0 7 1.976305021166412 0.0481202412648389 2.478155339805826 9.699029126213592 0.3163362844130395 0.5697991817121072 1.90604773194484 1.6682934217035197 0.7750405605100804 0.2910102683704078 0.2931808389803924 0.1155957163384056 0.2202973788945578 0.4690935769156698 0.7262550906181415 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..61eb16e1dc5957d0bce24bf1a6c375cec9ad691f --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 1344, + "title": "Average number of proteins per term", + "value": 15.146577380952381 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..af6fb87876dcbb22f00729d376312e1826e6e8c9 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6ca82df0420b124c454af76a4451abd6c04ef2eb --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,387 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.6418957340749074 5.486044779609316 4.110327444711227e-08 5.524127613810451e-05 5.52428008582629e-05 155 Q99595,Q9NS69,O60830,Q70HW3,Q14728,O43676,P13073,Q01650,P12235,Q96ES6,P21796,O15118,Q9HD20,Q8NEW0,P03886,Q9Y619,P45880,Q9H2D1,P56134,P20020,Q9Y487,P30536,O75964,P00403,Q9BZF3,Q93050,P24539,Q9P0J0,O15173,P06576,Q13423,P38435,P30825,Q9BZF1,Q9UBX3,P53985,Q15388,P47985,P16615,Q7KZN9,Q8IXU6,O14925,Q8NE01,Q9HC21,O96000,Q9UGP8,Q9UDW1,Q4KMQ2,Q8TB61,Q99829,Q8NHS3,Q9UJS0,Q9Y6M9,Q07820,O43772,O75306,Q5SR56,Q00325,Q96GC9,Q6P4A7,Q9Y277 61 +Ion transmembrane transporter activity 0.6332221433246878 4.458498723263175 8.253568857696791e-06 0.0110315436155142 0.0055463982723729 91 P13073,Q14728,Q70HW3,P12235,Q01650,Q96ES6,P21796,Q9HD20,Q8NEW0,Q9Y619,P45880,Q9H2D1,P56134,Q9Y487,O75964,P00403,Q93050,P24539,Q13423,P30825,Q9UBX3,P53985,Q7KZN9,P47985,P16615,Q9HC21,Q9UDW1,Q4KMQ2,Q8TB61,Q9UJS0,O43772,Q00325,Q6P4A7,Q9Y277 34 +Oxidoreductase activity 0.441410673081222 3.155215988085019 0.0016037932824164 0.8843548130589021 0.1207062819549802 210 P13073,Q9Y320,Q9BU89,O43676,O43169,Q06136,Q8N8N7,O43819,Q8NB78,P49327,P03886,Q709F0,Q9UHG3,P36551,Q15392,P14406,Q92947,O43396,P30519,P00403,P54886,Q9H7Z7,Q9NZ01,Q9P0J0,O95831,Q13423,Q9H3N1,Q6ZRP7,Q3SXM5,Q7KZN9,P47985,Q16850,P51648,O75874,Q8NBN7,O96000,Q9UDW1,O15254,P30837,P13674,Q9Y6M9,Q9BY49,Q15067,O00116,Q8TED1,O43175,O75306,Q15800,P09601,P48735,Q32P28,Q8NBX0,Q96CU9,P16435,Q14534,Q8N4Q0 56 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.961209964412814 2.828944238364937 0.00467018352802 0.998147888960302 0.1207062819549802 2 P30519 1 +L ornithine transmembrane transporter activity 0.9469750889679748 2.771584557913021 0.0055784181609248 0.99945699058776 0.1291863284287024 2 P30825 1 +Protein prenyltransferase activity 0.9262329059183336 2.6845128651103245 0.0072635587775033 0.9999444290436286 0.1328939125719118 3 Q92696 1 +Ribosomal protein s6 kinase activity 0.9227758007117488 2.673124551158895 0.007514834341864 0.9999604552744912 0.1328939125719118 2 Q15418 1 +Porin activity 0.9144362994496416 2.6334647491673215 0.0084518608629715 0.999988889020804 0.1336108299781553 4 P45880,P21796 2 +Wide pore channel activity 0.9144362994496416 2.6334647491673215 0.0084518608629715 0.999988889020804 0.1336108299781553 4 P45880,P21796 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.9110003559985812 2.6217355614655697 0.0087483281533315 0.999992566288641 0.1336108299781553 3 Q16850,Q15800 2 +Solute proton symporter activity 0.9056939501779356 2.6028951288222464 0.0092440225322001 0.9999962046971624 0.134404664652703 2 Q00325 1 +Organic hydroxy compound transmembrane transporter activity 0.8868327402135223 2.5246416098745805 0.0115816333109171 0.9999998413484328 0.1389490683391582 2 Q14728 1 +Cation transmembrane transporter activity 0.6537108116602728 2.524470027232668 0.0115872885514376 0.9999998425637407 0.1389490683391582 64 P13073,P12235,Q70HW3,Q96ES6,Q9HD20,Q8NEW0,Q9Y619,Q6P4Q7,P36542,P05023,P56134,P20020,Q9Y487,P00403,O75964,Q93050,P24539,P06576,P56385,Q13423,P30825,Q7KZN9,P47985,P16615,Q9HC21,Q9UDW1,Q4KMQ2,O43772,Q00325,Q9UM00,Q01650 31 +Azole transmembrane transporter activity 0.8832740213523226 2.509792841077282 0.0120802006294991 0.9999999194713196 0.1389490683391582 2 P30825 1 +Quaternary ammonium group transmembrane transporter activity 0.8832740213523209 2.5097928410772754 0.0120802006294993 0.9999999194713196 0.1389490683391582 2 O43772 1 +Phosphatidylinositol monophosphate phosphatase activity 0.8829181494661913 2.5083064932538246 0.0121311392446585 0.9999999248630108 0.1389490683391582 2 Q9Y217 1 +Guanylate kinase activity 0.8804270462633472 2.4978945633913305 0.0124933346405686 0.999999954100503 0.1389490683391582 2 O14936 1 +Ceramide binding 0.8796710450478393 2.4879387883052844 0.0128485845383023 0.9999999716997446 0.1389490683391582 4 P45880,P21796 2 +Peroxisome targeting sequence binding 0.876868327402136 2.482997605475146 0.0130281963385108 0.9999999778395688 0.1389490683391582 2 P40855 1 +Solute cation symporter activity 0.8782676645747398 2.48201035770653 0.0130643477823371 0.999999978904104 0.1389490683391582 4 Q00325 1 +Organic cation transmembrane transporter activity 0.8778582193968881 2.480279907570749 0.0131279282018599 0.9999999806538684 0.1389490683391582 4 O43772,Q70HW3 2 +Acyl coa oxidase activity 0.8740213523131766 2.471060727624604 0.0134712940253902 0.9999999878808296 0.1389490683391582 2 O15254 1 +Sphingolipid binding 0.8708881557511976 2.447932752486219 0.0143678469052745 0.9999999964291204 0.1389490683391582 5 P45880,P21796 2 +Phosphatidylglycerol binding 0.868195952911186 2.442714947525831 0.0145772460087956 0.999999997316165 0.1389490683391582 3 O60443 1 +Cardiolipin binding 0.868195952911186 2.442714947525831 0.0145772460087956 0.999999997316165 0.1389490683391582 3 O60443 1 +Voltage gated anion channel activity 0.864638653412805 2.4212569621186315 0.0154669396880733 0.9999999992028706 0.1398159846488756 5 P45880,P21796,Q9Y277 3 +Protein arginine omega n asymmetric methyltransferase activity 0.8570030746006474 2.3952608370250577 0.0166085454319484 0.9999999998323816 0.1398159846488756 3 Q86X55 1 +Fad binding 0.8569237295672498 2.3877678128946633 0.0169510472805936 0.9999999998950472 0.1398159846488756 9 O00116,Q8NB78,O15254,O95831,Q15392,Q14534 6 +P type calcium transporter activity 0.8540925266903988 2.3870205418069044 0.0169855421741054 0.999999999899882 0.1398159846488756 2 P16615 1 +O acetyltransferase activity 0.8530249110320369 2.3824945302759057 0.0171957874372516 0.9999999999248964 0.1398159846488756 2 Q8NF37 1 +Peptide receptor activity 0.849110320284709 2.3658783582941467 0.0179873532832426 0.9999999999745696 0.1398159846488756 2 Q99720 1 +Symporter activity 0.8491176135591496 2.351872859457452 0.0186791583271614 0.9999999999901368 0.14089513613692 6 Q96ES6,Q00325 2 +Lipid binding 0.4152933330478384 2.340869527471994 0.0192388890974604 0.9999999999954188 0.1420717964120153 125 Q9BZF3,P04083,O00264,O95772,A6NIH7,P21796,O43292,Q13432,Q9BQE5,Q96L92,O15254,O15173,P45880,O60313,O60443,P30086 16 +Sulfur compound transmembrane transporter activity 0.8442691792954037 2.3308573032959634 0.0197608853222834 0.99999999999776 0.142225155032436 6 Q70HW3,Q9UBX3 2 +Aromatic amino acid transmembrane transporter activity 0.8418708376787386 2.3306789207290985 0.0197702965098971 0.9999999999977888 0.142225155032436 3 P30825 1 +Tap binding 0.8394446422214354 2.3202786677099696 0.0203258073456831 0.9999999999989678 0.142225155032436 3 P01889,P10321 2 +G protein coupled receptor activity 0.8390886436454391 2.31875156426434 0.0204085108465781 0.9999999999990784 0.142225155032436 3 Q99720,Q6RW13 2 +Procollagen proline dioxygenase activity 0.8383577575630361 2.3156154791250283 0.0205792729246543 0.999999999999271 0.142225155032436 3 Q32P28 1 +Peptidyl proline dioxygenase activity 0.8383577575630361 2.3156154791250283 0.0205792729246543 0.999999999999271 0.142225155032436 3 Q32P28 1 +Inorganic molecular entity transmembrane transporter activity 0.6176726462552978 2.3137592187660796 0.0206809335124964 0.999999999999366 0.142225155032436 65 P13073,P12235,Q96ES6,P21796,Q9HD20,Q6P4Q7,P36542,P05023,P45880,P56134,P20020,Q9Y487,P00403,O75964,Q93050,P24539,P06576,P56385,Q13423,Q9UBX3,Q7KZN9,P47985,P16615,Q9UDW1,Q4KMQ2,Q00325,Q9UM00,Q9Y277 28 +Structural constituent of eye lens 0.836993934877142 2.3097605275362567 0.0209014157376468 0.9999999999995316 0.142225155032436 3 P08670 1 +Oxidoreductase activity acting on a heme group of donors 0.836301627606214 2.2962109775631645 0.0216638211824025 0.9999999999998356 0.1455808783457448 6 P00403,Q7KZN9,P16435 3 +Single stranded dna exodeoxyribonuclease activity 0.831918105136077 2.2838376628334927 0.0223810733109226 0.9999999999999386 0.1465040120764661 4 Q9UQ84 1 +Protein arginine n methyltransferase activity 0.8299626274656255 2.2753752069011544 0.0228834313698858 0.9999999999999692 0.1465040120764661 4 Q86X55 1 +Monooxygenase activity 0.8314392054280187 2.274666427126928 0.0229259479338139 0.999999999999971 0.1465040120764661 8 Q16850,Q9BU89,Q15800,P09601,P30519 5 +2 acylglycerol 3 phosphate o acyltransferase activity 0.8287646849412765 2.274347356461484 0.0229451099589821 0.9999999999999718 0.1465040120764661 3 Q8NF37,Q96N66 2 +Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 0.8259786476868334 2.2670241026550464 0.0233887533695209 0.9999999999999848 0.1465040120764661 2 Q8IXB1 1 +Active transmembrane transporter activity 0.6324233238571451 2.26033239516145 0.0238006288559571 0.9999999999999912 0.1465040120764661 62 P13073,P12235,O43676,Q96ES6,Q9HD20,P03886,P20020,P00403,Q9P0J0,Q9UBX3,P53985,Q7KZN9,P47985,P16615,Q15388,O96000,Q9UDW1,Q9Y6M9,O75306,Q00325,Q01650 21 +L amino acid transmembrane transporter activity 0.8279408009948177 2.2598668258451866 0.0238295173837033 0.9999999999999916 0.1465040120764661 9 Q9UJS0,P30825,Q9Y619 3 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.8246113455024844 2.2564190459476956 0.0240443999580577 0.9999999999999938 0.1465040120764661 3 P16435 1 +Protein transmembrane transporter activity 0.8251464061920454 2.2504588475959544 0.0244198330156841 0.9999999999999964 0.1475626102070714 11 Q99595,Q9NS69,O60830,Q15388,Q07820,O14925 6 +Anion channel activity 0.8249830393594202 2.246124533891227 0.0246960322916915 0.9999999999999974 0.1475626102070714 8 P45880,P21796,Q9Y277 3 +Protein transporter activity 0.8181637504149795 2.2277412710114386 0.0258977731775493 0.9999999999999996 0.1526605576781858 14 Q99595,Q9NS69,O60830,Q15388,O14925,Q9HD20 6 +Non membrane spanning protein tyrosine phosphatase activity 0.8156583629893351 2.222551361426858 0.0262460670458226 0.9999999999999996 0.1540380528802867 2 Q06124 1 +Palmitoyltransferase activity 0.8062727917603012 2.1722028427540487 0.0298403663651063 1.0 0.1650430139699708 4 P23786 1 +Macromolecule transmembrane transporter activity 0.804524359829712 2.159131212965489 0.030839988734066 1.0 0.1671310117669971 12 Q99595,Q9NS69,O60830,Q15388,Q07820,O14925 6 +Acylglycerol o acyltransferase activity 0.8012177568505819 2.1420126386425693 0.0321924650165297 1.0 0.1695355726063867 6 Q99943,Q8NF37,Q8NCC3,Q96N66 4 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.7978159461801269 2.135080821336234 0.0327544089254638 1.0 0.170627618588463 4 O15254,Q15067 2 +Lysophospholipid acyltransferase activity 0.7979078361422446 2.1311606044421745 0.0330759133141282 1.0 0.1712873997075039 5 Q99943,Q8NF37,Q96N66 3 +Phospholipid scramblase activity 0.7956620929526084 2.130432108597134 0.0331359553005587 1.0 0.1712873997075039 3 Q96GC9 1 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.7950115900706138 2.1227371851589685 0.0337758811465753 1.0 0.172603742437252 4 Q15418 1 +Isocitrate dehydrogenase activity 0.7930565378443377 2.1141219392840016 0.0345048537988892 1.0 0.1742904662334741 4 P48735 1 +Peptide antigen binding 0.7930989478700876 2.1059506390524474 0.0352086402708198 1.0 0.1744182156709815 6 P01889,Q15392,Q01650,P10321 4 +Threonine type endopeptidase activity 0.7930087995545346 2.103424254989008 0.0354287000581681 1.0 0.1744182156709815 8 P49721,P28074,P28072 3 +Threonine type peptidase activity 0.7930087995545346 2.103424254989008 0.0354287000581681 1.0 0.1744182156709815 8 P49721,P28074,P28072 3 +Ubiquinol cytochrome c reductase activity 0.7877227608072337 2.090576533852967 0.0365660411223545 1.0 0.1748923817382365 4 Q9UDW1 1 +Oxidoreductase activity acting on diphenols and related substances as donors 0.7877227608072337 2.090576533852967 0.0365660411223545 1.0 0.1748923817382365 4 Q9UDW1 1 +Organophosphate ester transmembrane transporter activity 0.7868768216843484 2.075803052058074 0.03791216998495 1.0 0.1800493161122716 8 Q9HC21,Q9H2D1,Q8TB61 3 +Nucleotide transmembrane transporter activity 0.7868768216843484 2.075803052058074 0.03791216998495 1.0 0.1800493161122716 8 Q9HC21,Q9H2D1,Q8TB61 3 +Beta 2 microglobulin binding 0.7754448398576494 2.04710422533155 0.0406478522090398 1.0 0.1876979439533081 2 P04439 1 +P type transmembrane transporter activity 0.7775800994486759 2.045636859419435 0.0407921121634238 1.0 0.1876979439533081 4 P20020,P16615 2 +Prenyltransferase activity 0.7780384900041349 2.042934472644688 0.0410589252397861 1.0 0.1876979439533081 5 Q92696,P49356 2 +Gpi anchor binding 0.7722419928825779 2.0329843584993665 0.0420541032912724 1.0 0.1909483608901019 2 O43292 1 +Trna methyltransferase activity 0.7749640734070233 2.0292084367943515 0.0424370646173952 1.0 0.1920120245653165 5 O75648 1 +Immunoglobulin binding 0.7722911760911196 2.0274250224822294 0.0426189650822432 1.0 0.1920120245653165 3 P17931 1 +C4 dicarboxylate transmembrane transporter activity 0.7707007326895203 2.0101414990900572 0.0444162149432656 1.0 0.1952958601604271 5 Q9UBX3 1 +Solute anion antiporter activity 0.7668748701943415 1.9979704474985436 0.0457198641367386 1.0 0.1985301458021007 4 P12235,P12236 2 +Translation activator activity 0.7645106394118953 1.987411250077534 0.0468768419973975 1.0 0.2012858646789209 4 Q9H074 1 +Nucleobase containing compound transmembrane transporter activity 0.7604930986429466 1.9546897026127945 0.0506197062429829 1.0 0.2099780407116329 10 P12235,Q9HC21,L0R6Q1,P51991,Q8TB61,Q9H2D1 6 +Leucine zipper domain binding 0.7533807829181514 1.949404347523298 0.0512471557549911 1.0 0.2112766175911292 2 Q96IZ0 1 +Lrr domain binding 0.7533807829181514 1.949404347523298 0.0512471557549911 1.0 0.2112766175911292 2 Q96IZ0 1 +Peptidyl proline 4 dioxygenase activity 0.7523131672598031 1.9446516435053969 0.0518169192014164 1.0 0.2123229859960477 2 P13674 1 +Procollagen proline 4 dioxygenase activity 0.7523131672598031 1.9446516435053969 0.0518169192014164 1.0 0.2123229859960477 2 P13674 1 +Dipeptidyl peptidase activity 0.7531865807233061 1.9423763837460035 0.0520915521271927 1.0 0.2127995320940639 3 Q9NY33 1 +Histone methyltransferase activity h3 k36 specific 0.746263345195737 1.9176761597923624 0.0551520864667938 1.0 0.2206083458671752 2 O96028 1 +Voltage gated channel activity 0.7515780420005341 1.913448160181928 0.0556907039800227 1.0 0.2214732246290376 10 P45880,P21796 2 +Transition metal ion binding 0.3686093876088849 1.9037679338907156 0.0569404144562843 1.0 0.2244220440740358 167 O75880,Q03164,Q9BU89,O43819,Q8N8N7,Q9UIQ6,Q8NB78,Q92696,Q5JTZ9,P00403,O43823,P53992,Q8TEY7,Q9NY33,P55786,Q5JPH6,Q10472,P51003,Q9NZ08,P49356,O60888,Q16850,Q9Y3Z3,Q99829,P13674,P46976,Q15800,Q5JRX3,Q32P28,Q8N4Q0 30 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7449823717258313 1.899754921023325 0.0574652892344662 1.0 0.2258285050617621 4 P46977 1 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.7416370106761583 1.8969982816192208 0.0578281648872245 1.0 0.226591993027492 2 Q9BV57 1 +Adp transmembrane transporter activity 0.7434234021553054 1.892723873078109 0.058394599917128 1.0 0.2281463438622676 4 P12235 1 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.7402135231316738 1.890627276610514 0.0586741164545068 1.0 0.2285739493184266 2 Q8NBQ5 1 +O acyltransferase activity 0.7452938942233851 1.8850396383644017 0.059424486427182 1.0 0.2307073055262196 9 Q8NCC3,Q96N66,Q8NF37,P23786,O15228,Q99943 6 +Nedd8 specific protease activity 0.7386970452118318 1.8773775663735115 0.060466363951309 1.0 0.2307073055262196 3 Q9BT78,Q96FW1 2 +Mitochondrial ribosome binding 0.7367006907737303 1.868389263869407 0.0617078324544688 1.0 0.2307073055262196 3 Q15070 1 +Ganglioside binding 0.7330960854092701 1.8587121925907408 0.0630679443048651 1.0 0.232054220300578 2 Q9NZJ7 1 +Glycosphingolipid binding 0.7330960854092701 1.8587121925907408 0.0630679443048651 1.0 0.232054220300578 2 Q9NZJ7 1 +Polynucleotide adenylyltransferase activity 0.732028469750906 1.8539163535041692 0.0637511278896165 1.0 0.2328302062055561 2 P51003 1 +Inorganic anion transmembrane transporter activity 0.735261814587289 1.839424662301848 0.0658527494521079 1.0 0.239205662874684 14 P45880,P21796,Q9UBX3 3 +G protein beta subunit binding 0.7284697508896911 1.837914203016552 0.066075048886891 1.0 0.2393662148355299 2 P48643 1 +Carbohydrate derivative transmembrane transporter activity 0.7305262228195526 1.82053142418652 0.0686781152652287 1.0 0.2479617076045141 7 P12235,Q8TB61,L0R6Q1 3 +Ion gated channel activity 0.7231316725978809 1.8138651274815705 0.0696984927199171 1.0 0.2479617076045141 2 Q4KMQ2 1 +Intracellular calcium activated chloride channel activity 0.7231316725978809 1.8138651274815705 0.0696984927199171 1.0 0.2479617076045141 2 Q4KMQ2 1 +Gated channel activity 0.7297180257585687 1.811074117304399 0.0701293794304342 1.0 0.2486909919643896 12 P45880,P21796 2 +Phosphatidylcholine binding 0.7268984227117428 1.8038173969240736 0.0712599376691178 1.0 0.2500609823166956 7 P21796 1 +Long chain acyl coa dehydrogenase activity 0.7222517590263006 1.79676384198108 0.0723731188808411 1.0 0.251993450196504 4 Q9NZ01 1 +Mhc protein binding 0.7249982233502977 1.792639548652912 0.0730305783403162 1.0 0.2536255743911758 8 P07437,Q9NUQ9,P68371,Q9BUN8 4 +Lipase inhibitor activity 0.7216918233950064 1.7882908639612485 0.0737290930703289 1.0 0.2540817976577489 5 P04083 1 +Purine nucleotide transmembrane transporter activity 0.7216315274829475 1.7825584155859984 0.0746582141649296 1.0 0.2553196942434236 6 P12235,Q8TB61 2 +Peptidase activity 0.3839737993951069 1.7735698750467723 0.0761343243345131 1.0 0.2577444128604174 102 P67812,P52888,P42785,P60900,Q9UIQ6,Q8TEY7,Q9NY33,P55786,P28074,Q9BT78,Q16740,Q96K76,P40818,P28072,O43292,Q15005,Q99829,Q8TCT9,O75844,Q96RU2,P49721,Q5JRX3,Q9BYT8 23 +Tetrapyrrole binding 0.720764421860837 1.7699911490118154 0.0767286151913033 1.0 0.2584467100938055 14 Q16850,O00264,O43169,Q9H7Z7,P09601,Q8WUJ1,O15173,P30519 8 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.7133960918607808 1.7446381306761491 0.0810478790638309 1.0 0.2637490301738227 6 P51812,Q15418 2 +Protein kinase b binding 0.7053380782918166 1.7333135442843162 0.0830399547036075 1.0 0.268282930580886 2 Q9UKG1 1 +Mhc class i protein binding 0.7108216827755366 1.729445263506325 0.0837294349286352 1.0 0.2698617758850978 7 P07437,P68371,Q9BUN8 3 +O methyltransferase activity 0.7073964095171886 1.7169331703396222 0.0859913833717223 1.0 0.2764890412717578 6 O60725 1 +Primary active transmembrane transporter activity 0.643889320814851 1.7128706309674904 0.0867363424108387 1.0 0.2775562957146839 45 P00403,P13073,Q7KZN9,P47985,P16615,O43676,Q15388,O75306,O96000,Q9HD20,Q9P0J0,P03886,Q9UDW1,P20020,Q9Y6M9 15 +Gtpase activating protein binding 0.7030725211525208 1.7090978247182853 0.087432830466001 1.0 0.2786637241594447 4 P07437 1 +Tau protein kinase activity 0.7028752384204994 1.7081925802155018 0.0876006148245713 1.0 0.2786637241594447 4 Q7L7X3 1 +Volume sensitive anion channel activity 0.6978647686832743 1.699309470918737 0.0892608890198669 1.0 0.2818734284273113 2 Q9C0H2 1 +Thiol oxidase activity 0.69562121751514 1.681748396608927 0.0926176390324799 1.0 0.2876340211565162 3 P07237,Q6ZRP7 2 +Phospholipase a2 inhibitor activity 0.6900067495671678 1.6560022207753828 0.0977213690897826 1.0 0.2968519592168251 3 P04083 1 +Udp glucosyltransferase activity 0.6926604257433249 1.6546915797085375 0.0979870759713876 1.0 0.2968519592168251 5 P13807,P46976 2 +Insulin receptor substrate binding 0.687544483985765 1.6521911098015425 0.0984955981929587 1.0 0.2968519592168251 2 P08069 1 +Oligosaccharyl transferase activity 0.6916140054640572 1.649848205885429 0.0989739863828018 1.0 0.2968951557875671 5 P46977,P04843 2 +Dicarboxylic acid transmembrane transporter activity 0.6903416309131747 1.6378280552386026 0.1014575673500037 1.0 0.3008749113700252 6 Q9UBX3 1 +Organic acid transmembrane transporter activity 0.6884323521282284 1.627156548316104 0.103703853551591 1.0 0.3008749113700252 20 P30825,Q9UJS0,Q9Y619,Q9H2D1,Q9UBX3,P53985 6 +Antigen binding 0.6842656869094691 1.6021521582726996 0.1091219664584488 1.0 0.3091718579674892 8 P01889,Q15392,Q01650,P10321 4 +Cadherin binding involved in cell cell adhesion 0.6847371509985093 1.5992079401871266 0.1097744066383437 1.0 0.3091718579674892 10 P04083 1 +Copper chaperone activity 0.6775197070934471 1.5985521646932574 0.1099201457999576 1.0 0.3091718579674892 3 O75880 1 +Metallochaperone activity 0.6775197070934471 1.5985521646932574 0.1099201457999576 1.0 0.3091718579674892 3 O75880 1 +Atp transmembrane transporter activity 0.6781586436441295 1.587408481176329 0.1124201596831711 1.0 0.3141220262249105 5 P12235,P12236 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.6739730572488591 1.5742943746928195 0.115419409668362 1.0 0.3211670529902248 24 Q16850,Q9BU89,Q15800,Q8NB78,P09601,Q32P28,P16435,P13674,P30519 9 +Mitogen activated protein kinase p38 binding 0.6700892662886435 1.5642487011793151 0.1177591741211045 1.0 0.3243203483991077 3 Q15750 1 +Amino acid transmembrane transporter activity 0.6771105713620706 1.5608948674640504 0.1185485585166525 1.0 0.3258267129782844 11 Q9UJS0,P30825,Q9Y619 3 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.6699404069008694 1.5491308014539842 0.1213502798734618 1.0 0.3283958567179058 5 Q9UHG3 1 +Nadh dehydrogenase activity 0.6735994422259632 1.5487657105547428 0.1214380511821422 1.0 0.3283958567179058 19 P03886,Q9Y6M9,O95831,O43676 4 +Oxidoreduction driven active transmembrane transporter activity 0.6641080016294456 1.544454028552791 0.1224783799279778 1.0 0.3298816485434914 27 P00403,P13073,Q7KZN9,P47985,O43676,O75306,O96000,P03886,Q9UDW1,Q9Y6M9 10 +Atpase coupled cation transmembrane transporter activity 0.6733096008484132 1.540240833203268 0.1235016599937657 1.0 0.3306498626127911 13 P16615,Q9HD20,P06576,P05023,P20020 5 +Anion transmembrane transporter activity 0.6318150755426667 1.5325605704993537 0.1253841628269241 1.0 0.3327878476877918 40 Q14728,P30825,Q01650,Q9HC21,P21796,Q9UJS0,Q9Y277,Q4KMQ2,Q8TB61,Q9Y619,P45880,Q9H2D1,Q9UBX3,P53985 14 +Copper ion binding 0.6638191312938165 1.5054823882382595 0.1322001014321081 1.0 0.3456749733944618 8 O75880,O43819,O60888 3 +Lys48 specific deubiquitinase activity 0.6545584045584057 1.484558028084158 0.1376609407791424 1.0 0.3558673278805961 4 Q9H8M7,O94966,Q93009 3 +Cholesterol binding 0.6619886538971456 1.4844606169739802 0.1376867637633259 1.0 0.3558673278805961 14 Q9BZF3,O95772,P21796,O15118,P45880,P30536 6 +Ephrin receptor binding 0.6523472091335093 1.482014426756335 0.1383364563149283 1.0 0.3560423857444025 3 P18031 1 +Calcium cation antiporter activity 0.6487544483985808 1.4735830831940846 0.1405938788965854 1.0 0.3596570503691948 2 O95202 1 +Proton transmembrane transporter activity 0.6335201247341016 1.4628183886782504 0.1435170799859439 1.0 0.3618892223285342 35 P00403,P13073,P12235,O75964,Q7KZN9,P47985,Q93050,Q96ES6,Q00325,P24539,Q9UDW1,Q13423,P56134,Q9Y487 14 +Phosphatidylinositol phosphate phosphatase activity 0.6493806236100007 1.4603895365842303 0.1441830468331302 1.0 0.3622093737265925 4 Q9NTJ5,Q9Y217 2 +Quaternary ammonium group binding 0.6531227804096149 1.445309037975533 0.1483711003569281 1.0 0.3699643021887039 11 P21796 1 +Phosphatidylinositol 3 kinase binding 0.6432894268423001 1.4398710508109818 0.1499038847514922 1.0 0.3724044752421543 3 P08069,O14654 2 +Potassium channel inhibitor activity 0.6422292938072369 1.4349321080526485 0.151306445079943 1.0 0.3751953176890101 3 Q96PU5 1 +Misfolded protein binding 0.6466065193764858 1.4099224639673975 0.1585625787660218 1.0 0.3846716712302047 13 Q13217,Q9GZP9,Q8IXB1,P48723,Q9BUN8,P46379 6 +Translation repressor activity mrna regulatory element binding 0.6392266295930504 1.3980337760023211 0.1621029246962191 1.0 0.3896224603572132 6 Q9BPZ3 1 +Metalloendopeptidase activity 0.6442521609712991 1.397235742241576 0.1623426918155055 1.0 0.3896224603572132 14 O43847,P52888,Q9Y4W6,P42892,Q5JRX3,P22695,Q9BYT8,O75844 8 +Lamin binding 0.6354048818710557 1.3702046723291652 0.1706230202113587 1.0 0.3992342201465922 8 Q9ULX6,P42166,Q5SNT2,P42167,O94901 5 +Ubiquitin specific protease binding 0.6330475334286095 1.3636267435307403 0.1726850706788067 1.0 0.3992342201465922 7 Q9BUN8,P46379 2 +Atpase coupled transmembrane transporter activity 0.6364913751657139 1.3592180409689207 0.1740775061005701 1.0 0.3992342201465922 18 Q15388,P16615,Q9HD20,P06576,P05023,P20020 6 +Steroid binding 0.6340535544582111 1.3565546942153448 0.1749227455776949 1.0 0.3992342201465922 22 Q9BZF3,O00264,O95772,P21796,O15118,O15173,P38435,P45880,P30536 9 +Transferase activity transferring sulphur containing groups 0.6287864466908002 1.348658877339098 0.1774465598407846 1.0 0.4001479470235143 6 O75648,Q5VV42 2 +Secondary active transmembrane transporter activity 0.633516606054626 1.343311065360872 0.1791712705717729 1.0 0.4020164930182405 17 P12235,P53985,Q96ES6,P53007,Q02978,Q00325,Q9UBX3,P12236,Q01650 9 +Active ion transmembrane transporter activity 0.6082327956323096 1.3306433767235106 0.183306382587131 1.0 0.4089283063722003 36 P00403,P13073,P12235,Q7KZN9,P47985,P16615,Q96ES6,P53007,Q02978,Q00325,P61421,Q9HD20,Q9UDW1,P06576,P05023,P20020,P12236 17 +Organic anion transmembrane transporter activity 0.6226407891564671 1.3291514353725815 0.1837980136850618 1.0 0.4089810105839787 28 Q14728,P30825,Q01650,Q9HC21,Q9UJS0,Q8TB61,Q9Y619,Q9H2D1,Q9UBX3,P53985 10 +Cyclin dependent protein serine threonine kinase regulator activity 0.6228533480892245 1.328111866016449 0.1841411540106279 1.0 0.4090672908930313 5 O95067,P49736,P11802 3 +Zinc ion binding 0.3420025018340636 1.3112471954254132 0.1897742620496614 1.0 0.4174412572745416 125 Q03164,Q6P179,P18031,Q8N8N7,Q8WWV3,Q9UIQ6,Q8NB78,Q92696,P36551,O95071,Q5JTZ9,O43823,P53992,Q8TEY7,Q9NY33,P55786,Q5JPH6,Q8NCC3,Q9Y4W6,Q9BWF3,Q9NZ08,Q9NUD5,P49356,Q8IXJ6,O43813,Q9Y3Z3,P19474,O75312,Q9Y6X9,Q99829,P42892,P09960,O95376,Q5JRX3,Q14527,Q8N4Q0 36 +Alcohol binding 0.6266114434507232 1.308561154666933 0.1906830465021047 1.0 0.418754925651681 17 Q9BZF3,O95772,P21796,O15118,P45880,P30536 6 +Macrolide binding 0.6127391686098387 1.272591845457471 0.2031629137431754 1.0 0.4389886753550285 6 Q96AY3,P62942 2 +Fk506 binding 0.6127391686098387 1.272591845457471 0.2031629137431754 1.0 0.4389886753550285 6 Q96AY3,P62942 2 +Translation repressor activity 0.6134206142915478 1.2603325630135491 0.2075494178214858 1.0 0.4448906181053859 9 Q9BPZ3,P00374,Q14011 3 +Phosphoric diester hydrolase activity 0.6135833871561742 1.25697143433656 0.2087639795917297 1.0 0.4467815104638293 10 Q8N2A8 1 +L ascorbic acid binding 0.6072055801295291 1.25420027534355 0.20976921982809 1.0 0.4482191278997663 5 Q32P28 1 +Oligopeptide binding 0.605654567306453 1.246866941791661 0.2124462899332977 1.0 0.4517845153011901 5 Q9H7Z7,O43813 2 +Metalloaminopeptidase activity 0.6099694060889111 1.2357409406667583 0.2165548742158147 1.0 0.4569069873564443 11 Q9NY33,P55786,P09960,Q9UIQ6,Q9NZ08 5 +Protein methyltransferase activity 0.6064367281209154 1.2158443007986433 0.2240442393256299 1.0 0.4639683476943707 23 Q03164,Q9BV86,O60725,O96028,O60678,Q9H7B4,Q86X55 7 +Dynactin binding 0.5985095925738478 1.2130738782699284 0.2251015760319259 1.0 0.464028041127549 5 P42858,Q9Y5X3 2 +S adenosyl l methionine binding 0.5907473309608482 1.203307894443896 0.228857195243378 1.0 0.464028041127549 2 Q9UJK0 1 +Solute sodium symporter activity 0.5903914590747326 1.2016437854959008 0.2295015695113536 1.0 0.464028041127549 2 P55011 1 +Structural constituent of postsynapse 0.5893238434163641 1.196651358650474 0.2314424733983078 1.0 0.464028041127549 2 P12814 1 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.6035264410581381 1.1958096715055138 0.2317708408696945 1.0 0.464028041127549 14 Q9BY49,Q8N8N7,Q9H7Z7,Q9NZ01,Q15392,Q8N4Q0 6 +Insulin receptor binding 0.5975324751736334 1.1943432562037255 0.2323437235445919 1.0 0.464028041127549 7 P18031,Q8WWQ0,Q06124,O14654 4 +Proteasome binding 0.600505286651003 1.1935925070277404 0.2326374064450691 1.0 0.464028041127549 10 O95456,P46379 2 +Phosphatidylcholine transporter activity 0.588256227758001 1.1916588066426157 0.2333950564004636 1.0 0.464028041127549 2 P48739 1 +Sphingolipid transporter activity 0.588256227758001 1.1916588066426157 0.2333950564004636 1.0 0.464028041127549 2 P48739 1 +Phosphatidylinositol bisphosphate phosphatase activity 0.5893064612739137 1.1871712115247852 0.2351600938591023 1.0 0.4668466265090598 3 Q9Y217 1 +Membrane insertase activity 0.5894446197789875 1.1701849675333242 0.2419265409509539 1.0 0.474354398923357 5 Q15070,Q9NPA0 2 +Passive transmembrane transporter activity 0.5932398004286094 1.1691425068325083 0.2423462204367488 1.0 0.474354398923357 28 O75964,Q9UM00,P56385,P21796,P24539,Q4KMQ2,P06576,P36542,P56134,P45880,Q9Y277 11 +Sterol binding 0.5989104000853669 1.1688542229401506 0.2424623696623589 1.0 0.474354398923357 17 Q9BZF3,O95772,P21796,O15118,P45880,P30536 6 +Glucocorticoid receptor binding 0.5832740213523123 1.1683595330320415 0.2426617708376102 1.0 0.474354398923357 2 Q04917 1 +Iron ion binding 0.5985264776708109 1.1677320384046717 0.2429148692218308 1.0 0.474354398923357 16 Q32P28,Q16850,Q9BU89,Q15800 4 +Histone methyltransferase activity 0.5968758523582952 1.1594507948700603 0.2462724822349613 1.0 0.4785598038751492 16 Q03164,Q9H7B4,Q9BV86,Q86X55 4 +Pre mrna intronic binding 0.5871091311487302 1.159134591995235 0.2464013275904786 1.0 0.4785598038751492 5 P22626 1 +Endopeptidase activity 0.4997540226540379 1.1406533865322483 0.2540141914902634 1.0 0.4898720065544943 59 P67812,P49721,Q8TEY7,P52888,P60900,P28074,Q16740,Q5JRX3,Q96K76,Q99829,P40818,O75844,Q8TCT9,P28072,O43292,Q96RU2 16 +Cdp alcohol phosphatidyltransferase activity 0.5793561682769901 1.1404641016793915 0.2540930002820736 1.0 0.4898720065544943 3 Q9Y6K0 1 +Acetylgalactosaminyltransferase activity 0.5790064061809759 1.138822531832129 0.2547771819803508 1.0 0.4898720065544943 3 Q10472 1 +Polypeptide n acetylgalactosaminyltransferase activity 0.5790064061809759 1.138822531832129 0.2547771819803508 1.0 0.4898720065544943 3 Q10472 1 +Flavin adenine dinucleotide binding 0.5885096351404443 1.1376771020061982 0.2552553382390088 1.0 0.4900902494188969 27 O00116,Q8NB78,P16435,O15254,Q709F0,O95831,Q15392,Q14534,Q92947 9 +Aminopeptidase activity 0.5861630666900666 1.1125461381874455 0.2659034041237231 1.0 0.4995460185050997 13 Q9NY33,P55786,P09960,Q9UIQ6,Q9NZ08 5 +Rna strand annealing activity 0.5767989398339386 1.1103628130671894 0.2668427158928876 1.0 0.4995460185050997 5 P51114 1 +Oxidoreductase activity acting on the ch ch group of donors 0.5825938466669673 1.1056804821910726 0.2688648408267486 1.0 0.4995460185050997 27 Q7KZN9,Q9BY49,Q15067,Q8N8N7,Q9H7Z7,Q9NZ01,P49327,O15254,Q709F0,Q15392,Q92947,Q8N4Q0 12 +Neurotrophin receptor binding 0.5697508896797154 1.1051359559738154 0.2691006825875686 1.0 0.4995460185050997 2 P62993 1 +Neurotrophin trk receptor binding 0.5697508896797154 1.1051359559738154 0.2691006825875686 1.0 0.4995460185050997 2 P62993 1 +Nf kappab binding 0.5843378700285586 1.103553315109543 0.2697869520116267 1.0 0.5001291910394845 13 O43823,P60900,Q96JB5,Q99829,Q86UE4 5 +Neurotransmitter receptor regulator activity 0.567971530249105 1.0968217030260223 0.2727193409231048 1.0 0.502683241409014 2 P49354 1 +Peptide binding 0.4425524778777471 1.090143456452069 0.2756499562175727 1.0 0.5068037498719805 69 Q6P179,O00264,Q9UIQ6,P01889,Q15392,P10321,P55786,Q9Y287,Q9H7Z7,Q9NZ08,P61758,Q15388,P04439,O43813,P40855,Q9NXR7,P42892,O15212,Q9BYT8,Q01650 20 +Proton transporting atp synthase activity rotational mechanism 0.5780466969623371 1.0847328254381072 0.2780400049103857 1.0 0.5091086738413603 10 O75964,P24539,P06576,P36542,P56134 5 +Proton channel activity 0.5780466969623371 1.0847328254381072 0.2780400049103857 1.0 0.5091086738413603 10 O75964,P24539,P06576,P36542,P56134 5 +Double stranded rna adenosine deaminase activity 0.5537366548042664 1.0303832666587518 0.3028301251685379 1.0 0.5370717433413696 2 Q9NZI8 1 +Adenosine deaminase activity 0.5537366548042664 1.0303832666587518 0.3028301251685379 1.0 0.5370717433413696 2 Q9NZI8 1 +Calcium dependent phospholipid binding 0.5656123673875924 1.0245587453765466 0.3055714387223935 1.0 0.5403789653196013 10 Q99829,P12429,P04083,P50995 4 +L serine transmembrane transporter activity 0.5501779359430581 1.0138020130224852 0.3106772345712845 1.0 0.5451047039997472 2 Q15758 1 +Protein carrier chaperone 0.5576044227767617 1.0039393399921834 0.3154078529475264 1.0 0.5496094241200759 7 Q15070,P40855 2 +Antiporter activity 0.5596426532917469 1.0012218969784104 0.3167195425386062 1.0 0.5499626165011458 9 P12236,P12235,Q02978,Q9UBX3 4 +Metalloexopeptidase activity 0.5643683865685643 0.9925479113488502 0.3209303198300968 1.0 0.5544091900406813 19 Q9NY33,P55786,P09960,Q9UIQ6,P36551,Q99829,Q9NZ08,O75844 8 +Cysteine type endopeptidase inhibitor activity 0.5561841328583912 0.9846184885004274 0.3248115046326527 1.0 0.5590862192168167 9 P51812,Q15418 2 +Electron transfer activity 0.5202406540140531 0.9684353145243376 0.3328270097481387 1.0 0.5691087800273517 47 P00403,P13073,Q7KZN9,P47985,Q6FI81,O43676,O43175,O75306,O96000,Q9P0J0,P03886,Q9UDW1,P16435,P14406,Q9Y6M9 15 +Atpase activator activity 0.5543842090548938 0.9605203660362336 0.336793386012804 1.0 0.5751592259227556 12 Q99543,Q8IXB1,Q96KC8 3 +Metallopeptidase activity 0.5406485325678115 0.9585837333339606 0.3377684904598279 1.0 0.5760924507335136 38 Q9NY33,Q9Y4W6,P52888,P55786,P42892,P09960,Q9UIQ6,Q5JRX3,P36551,Q99829,Q9BYT8,Q9NZ08,O75844 13 +Protein tyrosine phosphatase activity 0.5489388065563283 0.949890817869864 0.3421677329120269 1.0 0.5806482740325306 9 Q3ZCQ8,Q9Y217,Q06124,P24666 4 +Dynein heavy chain binding 0.5330960854092514 0.9344499722459724 0.3500718305739116 1.0 0.5890138695770787 2 Q9Y6G9 1 +Phospholipid transporter activity 0.5429187969498769 0.9342701570961854 0.3501645542327631 1.0 0.5890138695770787 7 Q96GC9,Q4KMQ2 2 +Intramembrane lipid transporter activity 0.5387112015239716 0.9308699538582192 0.3519208384483623 1.0 0.5904888974714093 5 Q96GC9 1 +C acyltransferase activity 0.5446237407359746 0.929249286360522 0.3527599104851542 1.0 0.5905437390236085 9 O15269 1 +Oxidoreductase activity acting on nad p h 0.5482651997889033 0.9171476173446544 0.3590652917231383 1.0 0.5987391464961512 26 Q7KZN9,O43676,O96000,P03886,O95831,Q13423,P16435,Q9Y6M9 8 +Palmitoyl protein hydrolase activity 0.5349974215505822 0.91347766626657 0.3609913744631474 1.0 0.6012049656486619 5 Q9NUJ1 1 +Racemase and epimerase activity 0.5293848425080232 0.9069151345014722 0.3644516771403201 1.0 0.606216651084889 3 Q8NCW5 1 +Transmembrane transporter binding 0.5461818890014911 0.9034423588394384 0.3662911673102653 1.0 0.6077720109444403 25 P16615,Q9Y4C2,P42858,P21796,Q96PU5,P30536 6 +Acyl coa dehydrogenase activity 0.5369254054335931 0.8990056193989394 0.3686496674912185 1.0 0.6082406249244917 8 Q92947,Q9NZ01 2 +Ww domain binding 0.528846153846154 0.8944163068612728 0.3710991908021452 1.0 0.6082406249244917 4 Q9Y2W2,P50570,Q9Y4G8 3 +Collagen binding 0.5346894936502277 0.8884098803934565 0.3743203125277379 1.0 0.6120273723081261 8 Q32P28,Q92791 2 +Cullin family protein binding 0.5267094017094079 0.8844841005747544 0.3764349415369428 1.0 0.6138836768582135 4 P63208,O60826,Q16531 3 +Molybdopterin cofactor binding 0.5243859024563858 0.8837597512433044 0.3768259177143052 1.0 0.6138836768582135 3 Q5VT66,Q969Z3 2 +Phosphotransferase activity for other substituted phosphate groups 0.5241465821895024 0.8725859403142204 0.3828888066815836 1.0 0.6194349757406458 4 Q9Y6K0 1 +Structural constituent of cytoskeleton 0.5398485865532933 0.8723590126114319 0.3830125532922581 1.0 0.6194349757406458 26 P07437,P68371,Q9BUF5,Q9BVA1 4 +Insulin like growth factor receptor binding 0.5167259786476845 0.8589236102263001 0.3903826624275446 1.0 0.6266063610677107 2 Q04917 1 +Atp dependent peptidase activity 0.5220052804906823 0.8528759417354208 0.3937281045229874 1.0 0.6287664081888243 5 Q16740 1 +Protein kinase a regulatory subunit binding 0.5239811354547272 0.8450440919451958 0.39808622161558 1.0 0.6338752337795022 7 Q9ULX6 1 +Demethylase activity 0.5204856054870899 0.8145492086920567 0.415330393877293 1.0 0.6512971872202366 9 Q16850 1 +Cation channel activity 0.5274175587466566 0.8075999757329558 0.4193209007144878 1.0 0.6560736793483953 18 O75964,P24539,Q4KMQ2,P06576,P36542,P56134,Q9UM00 7 +Fatty acid binding 0.5104480970546527 0.7744101919184131 0.4386882584413123 1.0 0.6800426982066018 8 O15254 1 +Cysteine type endopeptidase activity 0.5169807460359825 0.7502976620471548 0.4530754503970249 1.0 0.6919697787881834 21 Q96K76,O43292,Q8TEY7,P40818 4 +Exodeoxyribonuclease activity 0.5048694706667761 0.7412916713750092 0.4585166104940423 1.0 0.6986919778956836 9 Q9UQ84 1 +Hydrolase activity acting on ether bonds 0.4946744694086021 0.7091253807855825 0.4782466739113094 1.0 0.7173700108669641 7 P07099 1 +Lipase activity 0.5021014268942248 0.7037448628283819 0.481591676262699 1.0 0.7199768775273276 13 Q8N2A8 1 +Phospholipase activity 0.5021014268942248 0.7037448628283819 0.481591676262699 1.0 0.7199768775273276 13 Q8N2A8 1 +Phospholipid binding 0.3618236826960458 0.7018890148031729 0.4827483801662366 1.0 0.7209042477149135 76 P04083,P50995,Q8NCC3,Q9NZJ7,O14964,P21796,O43292,Q96L92,P35080,O76054,Q99829,Q9Y5X3,P45880,Q9BZF1,O60313,O60443,P30086 17 +Histone lysine n methyltransferase activity 0.4970169167011111 0.6979247024886901 0.4852242849761958 1.0 0.7216872885975694 10 Q9H7B4 1 +Lysine n methyltransferase activity 0.4970169167011111 0.6979247024886901 0.4852242849761958 1.0 0.7216872885975694 10 Q9H7B4 1 +Ferrous iron binding 0.4811387900355875 0.6976108142001282 0.4854206167352699 1.0 0.7216872885975694 2 P22830 1 +Scaffold protein binding 0.502587819817524 0.6963342805471092 0.4862195095970496 1.0 0.7220762661861156 15 Q9UQB8,P08670,Q9NZJ7 3 +Vitamin transmembrane transporter activity 0.4894663253026795 0.6935953490253604 0.4879360113027675 1.0 0.7230275625037702 6 Q9HC21,Q9H2D1 2 +Spectrin binding 0.48651474012948 0.6900941841680442 0.4901349603051756 1.0 0.7254861086455463 5 P35611 1 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.4775800711743817 0.6817758961147584 0.4953806679565087 1.0 0.7316391403665359 2 Q13630 1 +Co smad binding 0.4768683274021355 0.6786167816550699 0.497380706892264 1.0 0.7337866850309581 2 Q93008 1 +Guanyl nucleotide binding 0.3005957546132867 0.668118870808515 0.5040577169632985 1.0 0.7411964678322464 98 P07437,Q9BVA1,Q9Y5M8,Q9BUF5,P55010,P68371,O60313 7 +Glycolipid binding 0.4833062144960284 0.649447820127271 0.5160489632829961 1.0 0.753061679318509 8 O43292 1 +Channel inhibitor activity 0.4792400762317197 0.6474712588954293 0.517326989984638 1.0 0.7541078899559148 6 Q96PU5,P62942 2 +Molecular function activator activity 0.4892040130731047 0.6430785691019634 0.5201731196793031 1.0 0.757435181851553 13 Q99543,Q8IXB1,Q96KC8 3 +Camp binding 0.469206123175508 0.6338215778538941 0.5261972694995296 1.0 0.7612584824621828 3 Q9Y4G8,P13861 2 +Kinase inhibitor activity 0.4909618295527438 0.6324311680439804 0.5271051728284428 1.0 0.7617519917004594 17 O95684,P04792 2 +Pentosyltransferase activity 0.4883234487196648 0.6285440326814788 0.529647610760871 1.0 0.7637836790371358 15 Q13126,Q9ULX3,P43490 3 +Centromeric dna binding 0.4670701317194732 0.624438786800508 0.5323394592183703 1.0 0.7668426936650479 3 P43246,Q99661 2 +Mirna binding 0.4850038272907986 0.623522800675358 0.5329410237582466 1.0 0.7668872975707531 13 Q14671,Q8IWR0,Q9BWF3,P43243,P22626,P67809 6 +Poly a binding 0.4807668890952542 0.6163270490655032 0.5376786900003501 1.0 0.772051452308195 11 O14979,Q07666,Q71RC2 3 +Receptor tyrosine kinase binding 0.4814682500450009 0.6071458597471834 0.543754118102588 1.0 0.7799418727106492 13 O75312,Q06124 2 +Signal recognition particle binding 0.4692580280522953 0.60303043388698 0.5464884433244521 1.0 0.7811282205220196 6 Q9BUN8 1 +Cytoskeletal anchor activity 0.4656002262957576 0.5969602731172677 0.5505339044516573 1.0 0.7838109826091393 5 Q9UQB8 1 +Peptide hormone binding 0.4593788485519017 0.590895536503866 0.55459041685912 1.0 0.7879170404425553 3 P42892 1 +Transferase activity transferring alkyl or aryl other than methyl groups 0.4819753188965153 0.5897134018752521 0.5553828086989459 1.0 0.788209603897976 17 O00116,O43813,P14324,P21266,Q92696,P37268,P49356 7 +Leucine binding 0.4551601423487405 0.5836887125404977 0.5594297627243296 1.0 0.7928212137204248 2 Q8IWV7 1 +Structural constituent of muscle 0.4656960980295294 0.5787453666617582 0.5627609998855472 1.0 0.7961587198380793 7 P09493,Q12797,P60660,P14649 4 +Chloride channel inhibitor activity 0.4560341758632971 0.5764340026731151 0.5643218668270742 1.0 0.7966896943441047 3 Q9UNK0,Q9H4A3 2 +Nad dependent protein deacetylase activity 0.4573516859688129 0.5714252004435759 0.5677114507021672 1.0 0.8006339871392579 4 Q92769 1 +N methyltransferase activity 0.4774867509604596 0.5529899371290776 0.5802703007768015 1.0 0.811533074135298 22 Q03164,O96028,O75648,Q9H7B4,Q86X55 5 +Calcium ion transmembrane transporter activity 0.4657828219106896 0.5485437993909407 0.5833185634020519 1.0 0.8141019202620537 11 P16615,P20020,O95202,Q9UM00 4 +Hsp70 protein binding 0.4697188120614656 0.5474845491528828 0.5840458826133035 1.0 0.8142714380002903 14 Q99543 1 +Signaling receptor binding 0.2850676752159791 0.5420150818382071 0.5878081161948538 1.0 0.8174636551920587 145 P04083,Q07021,Q9UMX5,P62942,Q9BQE5,Q9BUN8,P01889,Q9NUQ9,Q8TEY7,P68371,Q9Y5X3,P06576,Q9NZ08,P07437,P08236,Q06124,P04439,O43813,O14936,O75312,P43490,Q92896,Q9NXR7,P27824,P46379,Q9BY49,Q9UBS4,Q3ZCQ8,Q96J02 29 +Transferase activity transferring one carbon groups 0.4400552123147542 0.5346963243628311 0.5928598635815026 1.0 0.8197568484089912 52 Q03164,O60725,Q9BV86,Q08J23,O96028,O60678,P31939,Q52LJ0,Q8N6R0,P21964,O75648,Q9H7B4,Q86X55 13 +Ubiquitin binding 0.4731451689182071 0.5272927053651137 0.5979903391300814 1.0 0.8243066828623891 26 Q8TEY7,O14964,Q9Y263,Q9Y679,O95071,Q96CS3,P04792,Q96FW1 8 +Cytokine receptor binding 0.4689236301350024 0.5244398286973582 0.5999726605236302 1.0 0.8245466986201926 18 Q3ZCQ8,Q9NZ08,Q9NXR7,Q96J02 4 +Glucosyltransferase activity 0.4506748862089212 0.5049841502170086 0.6135699683352203 1.0 0.8388993259842686 8 P13807,P46976 2 +Acyltransferase activity 0.451038890510906 0.5029179502615622 0.615021960229595 1.0 0.8393988589059364 45 Q86UY6,O15269,P53396,Q96N66,Q8NF37,Q969G3,P49327,P23786,Q9BWD1,Q96G23,O15228,Q99943 12 +Endoribonuclease activity producing 5 phosphomonoesters 0.4567513025665509 0.5016457084127433 0.6159167608629503 1.0 0.8393988589059364 12 Q8N2A8 1 +Amyloid beta binding 0.4550394444065719 0.5009914560601002 0.6163771359716597 1.0 0.8393988589059364 11 P61758,O15212,Q9Y287,O00264 4 +G protein beta gamma subunit complex binding 0.4382342470630162 0.5009113176672625 0.616433537009047 1.0 0.8393988589059364 3 P04899,Q14344 2 +Ubiquitin like protein ligase binding 0.2873069139307538 0.4962814873609864 0.6196958257162106 1.0 0.8421346711451841 97 P07437,Q9NQC3,O75306,Q96JB5,O76024,Q96HY6,Q96J02,Q96CS3,Q8TCT9,Q9BUN8,Q9Y679,P46379 12 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.4556195697548746 0.4901508085052118 0.6240271869485934 1.0 0.8448900996131584 13 Q8N2A8 1 +S adenosylmethionine dependent methyltransferase activity 0.4601391422125025 0.4881045409670813 0.6254757948018863 1.0 0.845132664770119 37 Q03164,O60725,Q08J23,O75648,Q9H7B4 5 +Ubiquitin like protein specific protease activity 0.4642173475732187 0.483850997380894 0.6284916194140475 1.0 0.8472344398119156 29 Q8TEY7,Q9BT78,Q96K76,P40818,Q96RU2 5 +Pdz domain binding 0.4507367581887706 0.4752679151136678 0.6345960249852405 1.0 0.8520450125675957 12 Q9UQB8,Q8IUD2,Q15067,P20020 4 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.4599152064944839 0.4718962763508507 0.6370008260557252 1.0 0.8528607732847479 21 P03886,Q9Y6M9,O43676 3 +Metal ion transmembrane transporter activity 0.4578819154404573 0.469460977321377 0.63874017143532 1.0 0.8528607732847479 19 P16615,Q9HD20,Q6P4Q7,P20020,Q9UM00 5 +Protein phosphatase regulator activity 0.4534903378642372 0.4633658684164169 0.6431021394120751 1.0 0.8557715597721078 16 Q86XL3,Q01105,P30154 3 +Calcium channel regulator activity 0.4335072212209709 0.4600920900935221 0.645450121419894 1.0 0.8580464522139837 5 P62942 1 +Insulin binding 0.4209964412811426 0.4414445275255421 0.6588912124902353 1.0 0.8652434321680589 2 P08069 1 +Sterol transporter activity 0.4371384691581396 0.4394077273368615 0.6603661283775604 1.0 0.865884952721406 9 Q9BZF3,P30536,O15118 3 +Endopeptidase regulator activity 0.4537629113843265 0.4378004277690597 0.6615309608494142 1.0 0.8665668726916304 23 Q15418,P51812,P30086 3 +Polyubiquitin modification dependent protein binding 0.4411461653617996 0.433919944201878 0.6643465762848497 1.0 0.8694077882442435 12 P46379 1 +Hormone binding 0.4334347648313446 0.4321904045126123 0.6656030327775411 1.0 0.8702047432422327 8 P05023,P30536,P42892 3 +Adenylyltransferase activity 0.4303612932957289 0.4280895035118191 0.6685859584617533 1.0 0.8715611330481051 7 Q9NVV4,O43252,P51003 3 +Regulatory rna binding 0.4431698695502155 0.4234856719611897 0.6719409501465503 1.0 0.8750858885629492 15 Q14671,Q8IWR0,Q9BWF3,P43243,P22626,P67809 6 +Cell cell adhesion mediator activity 0.4425875522019771 0.4153105754535052 0.677914560424753 1.0 0.878608649190808 16 P04083 1 +Protease binding 0.4479479579989408 0.4136216004490444 0.6791512514918738 1.0 0.8793634701397672 22 Q9BUN8,P04080,P46379,Q9NZJ7 4 +Mrna 3 utr au rich region binding 0.4341304916314155 0.4042766303842693 0.6860093084904886 1.0 0.8856834876188441 12 P31483,Q01085,Q14103,Q96B26,Q92945 5 +Exopeptidase activity 0.4473815724078462 0.4007302971135816 0.6886187021429171 1.0 0.886596334140273 29 Q9NY33,P55786,P42785,Q9UIQ6,Q99829,O75844 6 +Vitamin b6 binding 0.4389660590202759 0.3996300647291237 0.6894290091617656 1.0 0.886596334140273 16 O15269 1 +Metallocarboxypeptidase activity 0.4153399610834894 0.3973269789199202 0.6911263550267761 1.0 0.886596334140273 4 Q99829 1 +Mrna 3 utr binding 0.4251889113690156 0.3954785199751771 0.6924897709331619 1.0 0.886596334140273 49 P07910,P51116,P31483,Q14011,P35637,Q01085,P16989,Q14103,P48643,Q71RC2,P51114,Q96B26,Q9BWF3,Q9Y6M1,Q92945,P22626,Q92804,Q6PKG0 18 +Protein tyrosine kinase binding 0.4373077821322329 0.3924996534047928 0.6946890673912827 1.0 0.8883559529722967 16 Q07666,O75312,Q06124 3 +Glutathione transferase activity 0.4185037045164113 0.3892154581720808 0.6971167692959415 1.0 0.8892670314593142 6 P21266,O14880,O43813 3 +Molecular transducer activity 0.4440260266092441 0.3855596623431929 0.6998228122944288 1.0 0.891273197123449 31 Q99720,P15260,Q6RW13,O15118,Q9UGP8,P49327,Q4VCS5,O15173,Q15629,Q9BUN8,P30536 11 +Minor groove of adenine thymine rich dna binding 0.414841268331949 0.3849343123213521 0.7002860834541385 1.0 0.891273197123449 5 Q03164 1 +Omega peptidase activity 0.4342227868802699 0.3459284390695161 0.7293964953095613 1.0 0.9153210921531748 24 Q96K76,Q8TEY7,P40818,Q96RU2 4 +Rna 7 methylguanosine cap binding 0.4052294021548341 0.3376970354193129 0.7355915090520218 1.0 0.919092688933171 6 Q7L576 1 +Fibronectin binding 0.3879003558718933 0.3152259069370741 0.7525901366415644 1.0 0.9306368164901058 2 Q53GQ0 1 +Carboxylic ester hydrolase activity 0.4276885270307071 0.3120827849554199 0.7549776092478377 1.0 0.9326193996590936 26 Q9HDC9,Q8N2K0,Q8NCC3,Q9NUJ1,Q9Y3E5,P35790,Q15165,Q5JTZ9,Q9BW92 9 +Atpase binding 0.4276859531636494 0.3102253332131873 0.7563896070896274 1.0 0.9330576039911496 27 Q93050,Q16740,O76024,Q8IXB1,P40855,Q9BUN8,Q9Y487 7 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.3782918149466218 0.2812805140510799 0.7784952547629294 1.0 0.946019550091661 2 O60762 1 +Ubiquitin like protein binding 0.4195355942814249 0.2700789173103123 0.7870995411655921 1.0 0.9498748053023524 30 Q8TEY7,O14964,Q9Y263,Q9Y679,O95071,Q96CS3,P04792,Q96FW1 8 +Inositol phosphate phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Inositol polyphosphate 5 phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Phosphatidylinositol trisphosphate phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Inositol trisphosphate phosphatase activity 0.3722419928825666 0.2606150971246125 0.7943893461010745 1.0 0.9498748053023524 2 Q10713 1 +Enzyme regulator activity 0.2711950339805341 0.2434033329875557 0.8076929620886399 1.0 0.9566625472209468 212 P04083,Q9P035,Q9NZJ7,Q14C86,Q01105,O43169,P61289,O43924,P55010,Q7L7X3,Q86XL3,O95067,Q12972,O95684,Q9BXK5,P30154,Q8IZ81,Q15042,P13489,Q96CS3,Q14155,P04792,P30086,A4D1U4,Q15418,Q9Y263,P80303,P51812,Q02750,Q66K14,Q13217,P04080,Q5JRX3,Q9Y679 34 +Glucose binding 0.379027412843247 0.2430712616976634 0.8079501935033502 1.0 0.9566625472209468 6 P13807 1 +Aminoacyl trna editing activity 0.3847142691015993 0.2369160767503564 0.8127218975640693 1.0 0.9573165909957136 9 Q5JTZ9,Q9BW92 2 +Oxidoreductase activity acting on a sulfur group of donors 0.4096442258276287 0.2342139138068088 0.8148189137468744 1.0 0.9574732324640826 26 Q9Y320,O43819,Q8IXB1,Q9UHG3,Q9H3N1,O43396,Q6ZRP7 7 +Protein kinase a binding 0.3923569049905659 0.2333779004271769 0.8154679723265252 1.0 0.9574732324640826 13 Q9ULX6 1 +Cell adhesion mediator activity 0.4001048622366413 0.2301905383720815 0.8179437137527907 1.0 0.9574732324640826 18 P04083 1 +Alpha tubulin binding 0.3825047116423659 0.2292494416925027 0.8186750467196875 1.0 0.9574732324640826 9 Q7L7X3 1 +Transcription coactivator binding 0.3645425418298353 0.2248699002688486 0.8220804857335 1.0 0.9590939000224168 3 Q00059,P42224 2 +Cyclin binding 0.384692835782989 0.2209646225248621 0.8251199792548998 1.0 0.9593090416250736 11 Q96JB5,O14976,P11802 3 +Mitogen activated protein kinase binding 0.3713158406103087 0.2172386171620713 0.828022391059801 1.0 0.9603147172983526 6 Q96JB5 1 +Complement binding 0.3620505517977956 0.2168870180742408 0.8282963948887399 1.0 0.9603147172983526 3 Q07021,P35232 2 +Opsonin binding 0.3620505517977956 0.2168870180742408 0.8282963948887399 1.0 0.9603147172983526 3 Q07021,P35232 2 +Nad binding 0.4055238934512009 0.2121661955444363 0.8319773784118603 1.0 0.9603147172983526 28 O43175,O75874,P48735,P30837,Q13423 5 +Ether hydrolase activity 0.3663234835771313 0.2106887178592291 0.8331301788466363 1.0 0.9603147172983526 5 P07099 1 +Epoxide hydrolase activity 0.3663234835771313 0.2106887178592291 0.8331301788466363 1.0 0.9603147172983526 5 P07099 1 +Calcium ion binding 0.3305560774261725 0.2036201385959776 0.8386503545114161 1.0 0.9625500225989267 71 Q96AY3,O43852,P04083,P16615,Q8IYU8,Q14257,Q8NF37,Q96A33,P80303,Q9BPX6 10 +Hydrolase activity acting on ester bonds 0.2642998068368764 0.1969312724019563 0.8438813210147229 1.0 0.9636051764590736 143 Q9HDC9,Q9Y217,Q969T7,P24666,P18031,Q9NPH0,Q9NUJ1,P49327,Q12972,P05023,Q5JTZ9,Q5RKV6,Q8N2A8,Q8N2K0,Q8NCC3,Q9ULX3,Q9H857,Q13555,Q06124,Q9Y3Z3,Q9NQT4,Q9NTJ5,Q9BQP7,P09601,Q9UQ84,Q3ZCQ8,P35790,Q96B26,Q15165,Q92889 30 +3 5 dna helicase activity 0.3698244685021192 0.1951036653477749 0.8453117931867264 1.0 0.9636051764590736 8 Q8N3C0,Q14566 2 +Ribosomal large subunit binding 0.3538753352951483 0.1816307908121216 0.8558724831821221 1.0 0.9694847958703317 4 P98179,Q9NTK5 2 +Hydrolase activity hydrolyzing n glycosyl compounds 0.3579558317556174 0.1748924194122139 0.8611641669049162 1.0 0.9717923092529028 6 O43598,P13051 2 +Dioxygenase activity 0.3785641797685382 0.1712716297142781 0.8640101870399579 1.0 0.9722585451305564 15 Q32P28,P13674 2 +Molecular function regulator 0.2599344553117609 0.1679114512441073 0.8666529412476294 1.0 0.9730840042078646 268 P04083,Q9UMX5,Q9P035,Q9NZJ7,Q14C86,Q01105,O43169,P62942,P61289,O43924,P55010,Q7L7X3,Q86XL3,O95067,Q12972,O95684,Q9BXK5,P30154,Q8IZ81,Q15042,Q99543,Q8IXB1,Q96CS3,Q14155,P04792,P30086,A4D1U4,Q15418,Q9Y263,P80303,P43490,Q96KC8,P51812,Q02750,Q66K14,Q13217,P04080,Q5JRX3,Q96PU5,Q9Y679 40 +N acyltransferase activity 0.3805150575237066 0.1651258017575022 0.8688449649048018 1.0 0.974076885748186 17 Q96G23,Q86UY6 2 +Poly purine tract binding 0.3709670978967739 0.1528996729790498 0.8784773938024362 1.0 0.9762470770760724 14 O14979,Q07666,Q71RC2 3 +Lipid transfer activity 0.3504469455659823 0.1525049332808994 0.8787886997553342 1.0 0.9762470770760724 6 P30536 1 +Translation initiation factor binding 0.3743144586904967 0.1504913648105249 0.8803769630378142 1.0 0.9762470770760724 16 O75312,Q9Y4P3,P55010 3 +Ubiquitin conjugating enzyme binding 0.3473911128808916 0.1436966064893894 0.8857400510173834 1.0 0.9762470770760724 6 Q9Y679 1 +Beta tubulin binding 0.3732541474186436 0.1406707413360274 0.8881300602446418 1.0 0.9762470770760724 17 P50402,Q9UKG1,P42858,Q7L7X3,P48643 5 +Phosphatase regulator activity 0.3761644705284515 0.1384989639483439 0.8898460883752775 1.0 0.9762470770760724 19 Q86XL3,Q01105,P30154 3 +Endoribonuclease activity 0.376104627441309 0.1382970421409086 0.8900056630787045 1.0 0.9762470770760724 19 Q8N2A8,Q9UQ84 2 +Ionotropic glutamate receptor binding 0.3395083719273168 0.1308920049797531 0.8958607393706233 1.0 0.9765100030122608 5 P27824,Q15334,O75955,Q13501 4 +Amp activated protein kinase activity 0.3266903914590835 0.1249942404194677 0.9005281100594869 1.0 0.976958093885786 2 Q13131 1 +Calcium dependent protein binding 0.3702834242816055 0.1248614438250248 0.9006332428009591 1.0 0.976958093885786 18 P12429,O76024,P04083,P50995 4 +Camp dependent protein kinase activity 0.3268066927732351 0.1159649066630318 0.9076803545299136 1.0 0.9799317664090772 3 Q13131,P54619 2 +Cyclic nucleotide dependent protein kinase activity 0.3268066927732351 0.1159649066630318 0.9076803545299136 1.0 0.9799317664090772 3 Q13131,P54619 2 +K63 linked polyubiquitin modification dependent protein binding 0.3239587041651871 0.1088440756972481 0.91332616411575 1.0 0.9835820228938844 3 Q6P2Q9,Q13501 2 +Histone serine kinase activity 0.3181494661921799 0.1038851685998309 0.9172604771610628 1.0 0.9861592910461224 2 Q13131 1 +Protein disulfide isomerase activity 0.3412489926628901 0.1021289283277926 0.9186543395757034 1.0 0.9861592910461224 9 Q92643,Q6ZRP7 2 +K48 linked polyubiquitin modification dependent protein binding 0.3240740740740744 0.1000800093874244 0.920280805839798 1.0 0.9871168420181072 4 P55072,Q9NRR5,Q92890 3 +Protein deacetylase activity 0.3267965506418522 0.097853071286865 0.9220489647607468 1.0 0.9874722627700888 5 Q92769 1 +Sh3 domain binding 0.3596952136242923 0.0978119547136794 0.92208161441701 1.0 0.9874722627700888 17 O43813,Q16204,O75525,P40818,O75368 5 +2 oxoglutarate dependent dioxygenase activity 0.3466646640604902 0.0941993892264128 0.9249507699448496 1.0 0.989756237902769 12 Q32P28 1 +17 beta hydroxysteroid dehydrogenase nadplus activity 0.3194444444444463 0.0889748697702836 0.9291018819107256 1.0 0.99203778875182 4 Q8NBQ5,Q53GQ0,P51659 3 +Estradiol 17 beta dehydrogenase activity 0.3194444444444463 0.0889748697702836 0.9291018819107256 1.0 0.99203778875182 4 Q8NBQ5,Q53GQ0,P51659 3 +Ribosome binding 0.3763663609298215 0.0843050656116728 0.9328138849670664 1.0 0.9937868550259948 35 Q99543,Q15070,P46379 3 +Plus end directed microtubule motor activity 0.3246483059889178 0.0838772520178781 0.9331540260735158 1.0 0.9937868550259948 6 P33176,Q15058 2 +Rna polymerase iii transcription regulatory region sequence specific dna binding 0.3085409252669107 0.0818807160371764 0.9347415693126402 1.0 0.9942791897058004 2 P42345 1 +Mdm2 mdm4 family protein binding 0.3232815476509126 0.0806132048087252 0.9357495644662892 1.0 0.9942791897058004 6 Q96JB5 1 +Nadplus binding 0.3232359230220886 0.0805049045038436 0.9358356956680338 1.0 0.9942791897058004 6 Q16836,Q8IXJ6,Q7Z2W4,P00367,P40939 5 +Molecular function inhibitor activity 0.333382019344294 0.0740247216482852 0.9409907141919454 1.0 0.9989664453980842 10 Q96PU5,P62942,Q9H4A3 3 +Annealing activity 0.3216528091868329 0.0610543016111643 0.9513159632454722 1.0 1.0 8 P51114 1 +Nucleoside binding 0.3102956893480556 0.0598281773057388 0.9522924835230157 1.0 1.0 5 O43707,P30876,Q9NW08,Q9H9Y6 4 +Lysophospholipase activity 0.304271197950602 0.0556356162062597 0.9556320908041424 1.0 1.0 4 Q8NCC3 1 +Peptidase regulator activity 0.3638678336889774 0.0523849784600702 0.9582219431349186 1.0 1.0 29 P61289,P04080,Q15418,P51812,P30086 5 +Signaling receptor regulator activity 0.3345393485518469 0.0415557637223475 0.9668528381914324 1.0 1.0 15 P43490 1 +Enzyme inhibitor activity 0.3151389133155787 0.0368016681634904 0.9706431439489492 1.0 1.0 69 O95684,P04083,Q01105,P51812,Q13217,P04080,O43924,Q15418,Q96CS3,Q12972,P04792,P30086 12 +Microtubule minus end binding 0.2945156695156677 0.0366898293689615 0.9707323181722792 1.0 1.0 4 Q96CW5,Q9UPN3,Q9BSJ2 3 +Phosphatidylinositol bisphosphate binding 0.3236866394231379 0.0293460689002919 0.9765885850386952 1.0 1.0 13 O60443,Q9Y5X3 2 +Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 0.2942643391521161 0.0282405949830874 0.9774702600100192 1.0 1.0 5 Q8NBQ5,Q53GQ0,P51659,Q99714 4 +Cysteine type peptidase activity 0.3594297555868629 0.0178940626805562 0.9857233655516048 1.0 1.0 39 Q8TEY7,Q9BT78,Q96K76,P40818,O43292,Q96RU2 6 +S100 protein binding 0.3008718760527624 0.017819117526645 0.9857831536001004 1.0 1.0 8 P16615 1 +N6 methyladenosine containing rna binding 0.2909819316881291 0.0146847769650675 0.988283664272581 1.0 1.0 6 P22626 1 +Structural constituent of nuclear pore 0.3288362160915045 0.0026917235616749 0.9978523179216512 1.0 1.0 19 Q9BTX1,Q9BW27,Q9BVL2,P57740,Q12769,Q99567,Q8N1F7 7 +2 iron 2 sulfur cluster binding 0.2956733653532984 0.0013711754427824 0.9989059606268732 1.0 1.0 9 P47985,Q6FI81,P21912 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..234797aa7f45e9c64ac0884353e8382d67c5d024 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromatin insulator sequence binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor activity", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Igg binding", "Immune receptor activity", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interferon receptor activity", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin v binding", "Myristoyltransferase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreduction driven active transmembrane transporter activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphatidylserine flippase activity", "Phosphatidylserine floppase activity", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion antiporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Potassium proton antiporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein glutamic acid ligase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein hormone receptor activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase inhibitor activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Thyroid hormone transmembrane transporter activity", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridylyltransferase activity", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in cardiac muscle cell action potential", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Zinc ion binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8A", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATXN2L", "AUP1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CENPF", "CEP44", "CEP55", "CEPT1", "CERS2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "COG2", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FAM49B", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GIGYF2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPR107", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIAA1147", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MAK16", "MANBA", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMS19", "MOGS", "MORC2", "MORF4L1", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL47", "MRPL51", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NF1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIPK1", "RMDN1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCB", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STMN1", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TECR", "TELO2", "TERF2IP", "TES", "TFAM", "TFB1M", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TK1", "TKT", "TLN1", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM192", "TMEM201", "TMEM43", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC21B", "TTC26", "TTC4", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL5", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UCHL5", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS25", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "VWA8", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WFS1", "WIZ", "WNK1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512B", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABHD10", "ABHD12", "ACAD11", "ACAT2", "ACLY", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACTN1", "ACTN4", "ADD1", "ADI1", "AFG3L2", "AGPAT1", "AGPS", "AGTRAP", "AIFM1", "AKAP8", "AKAP8L", "ALDH18A1", "ALDH1B1", "ALDH3A2", "AMOT", "ANKLE2", "ANO6", "ANXA1", "ANXA11", "ANXA3", "APMAP", "APOL2", "APPL1", "ARHGEF7", "ARIH2", "ASCC3", "ASPH", "ATIC", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "AUP1", "BABAM2", "BAG6", "BAIAP2", "BCL2L13", "C1QBP", "CALU", "CAMK2G", "CANX", "CARM1", "CASK", "CCDC22", "CCDC47", "CCDC6", "CCNB2", "CCT5", "CDK4", "CDK5RAP3", "CDKAL1", "CEPT1", "CERS2", "CHKA", "CIAPIN1", "CIRBP", "CLPP", "CNNM3", "CNNM4", "COMT", "COPS4", "COX15", "COX2", "COX4I1", "COX7A2", "CPNE1", "CPOX", "CPT2", "CSTB", "CUTA", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DDB1", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DHFR", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNM2", "DNPH1", "DOHH", "DPM1", "DPP3", "DYNC1LI1", "EARS2", "ECE1", "EIF5", "ELMOD2", "EMC7", "EMD", "EPHX1", "ERAP1", "ERAP2", "ERC1", "ERCC4", "EXO1", "EXOSC5", "EXOSC6", "EXOSC8", "FAF2", "FAM49B", "FAM98B", "FASN", "FDFT1", "FDPS", "FECH", "FGFR1OP", "FKBP10", "FKBP1A", "FLOT1", "FNTA", "FNTB", "FOXRED1", "FUS", "FXR1", "FXR2", "GAK", "GALNT1", "GAPVD1", "GCDH", "GGCX", "GLG1", "GLUD1", "GNA13", "GNAI2", "GNPAT", "GPAA1", "GPX8", "GRB2", "GSDME", "GSTM3", "GUSB", "GYG1", "GYS1", "HACD3", "HADH", "HADHA", "HDAC2", "HGS", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HM13", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSPA13", "HSPB1", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IGF1R", "IGF2BP1", "IGF2BP2", "IRS4", "ITCH", "ITM2B", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA1147", "KIF14", "KIF2C", "KIF5B", "KMT2A", "LANCL1", "LARP1", "LARP4", "LETM1", "LGALS3", "LLGL1", "LNPEP", "LPCAT1", "LTA4H", "MACF1", "MAP2K1", "MARC1", "MARC2", "MATR3", "MBOAT7", "MCL1", "MCM2", "MCM6", "METTL13", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MGME1", "MGST3", "MICU1", "MICU2", "MINDY3", "MORC2", "MSH2", "MSMO1", "MTAP", "MTCH1", "MTDH", "MTMR6", "MTOR", "MTPAP", "MYL6", "MYL6B", "NAA40", "NAMPT", "NAXE", "ND1", "NDC1", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NEDD4L", "NENF", "NLN", "NNT", "NOB1", "NPC1", "NPEPPS", "NRDC", "NSD2", "NSUN2", "NT5C3B", "NT5DC2", "NTMT1", "NUCB2", "NUP107", "NUP160", "NUP58", "NUP85", "NUP88", "NUP93", "OLA1", "OPA1", "OSBPL6", "OSBPL8", "OTUB1", "OXA1L", "P3H1", "P3H4", "P4HA1", "P4HB", "PAIP1", "PAIP2", "PAPOLA", "PAPSS1", "PAWR", "PCYOX1", "PDE6D", "PEBP1", "PECR", "PEX19", "PFDN6", "PFN2", "PGRMC1", "PGRMC2", "PHB", "PHGDH", "PHIP", "PIGK", "PITPNB", "PITRM1", "PLA2G15", "PLAA", "PLD6", "PMPCA", "POLR1B", "POLR2B", "POLR3B", "PON2", "POR", "PPP1R8", "PPP2R1B", "PRCP", "PRKAA1", "PRKAG1", "PRKAR2A", "PRMT3", "PRPF8", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSME3", "PSMG1", "PTGES2", "PTGR2", "PTPN1", "PTPN11", "PTRH2", "PUM1", "QSOX2", "RAB3GAP1", "RABGGTA", "RAPGEF2", "RBM3", "RBM4", "RCN2", "RDH13", "RNH1", "RPN1", "RPS6KA1", "RPS6KA3", "RTN4", "RTN4IP1", "SACM1L", "SAMHD1", "SCCPDH", "SCO1", "SCO2", "SDHB", "SEC11A", "SEC14L2", "SEC24C", "SEC63", "SET", "SFXN4", "SH3BGRL", "SIGMAR1", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A6", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC7A1", "SLC7A5", "SMARCE1", "SMYD3", "SNX27", "SNX5", "SPCS2", "SPTLC1", "SQLE", "SQSTM1", "SRPRB", "STARD3NL", "STAT1", "STT3A", "STX8", "SUN1", "TAB1", "TAF15", "TAOK1", "TARS2", "TBC1D9B", "TBL2", "TCAF1", "TECR", "TFAM", "THOP1", "TIA1", "TIAL1", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TMCO1", "TMEM201", "TMPO", "TMX1", "TMX2", "TOMM20", "TOMM22", "TPM1", "TRAM1", "TRIM21", "TRMU", "TSPO", "TSR3", "TSTA3", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TXNL1", "UBQLN4", "UBR1", "UBR5", "UFD1", "UNC119", "UNC119B", "UNG", "UQCR10", "UQCRC2", "UQCRFS1", "USP19", "USP28", "USP33", "USP47", "USP7", "USP8", "USP9X", "VBP1", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "WBP11", "WFS1", "WNK1", "YBX1", "YBX3", "YWHAH", "ZADH2", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_hp/advanced/idx2term.json b/msigdb_hp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bd6fc6fbfa9d7f311e1aa90f87f3161014575c1d --- /dev/null +++ b/msigdb_hp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Abnormality of the mitochondrion", "1": "Abnormal circulating protein concentration", "2": "Abnormality of skin pigmentation", "3": "Abnormality of the cerebrospinal fluid", "4": "Hypertrophic cardiomyopathy", "5": "Increased serum lactate", "6": "Abnormal muscle fiber morphology", "7": "Functional motor deficit", "8": "Abnormal myocardium morphology", "9": "Progressive external ophthalmoplegia"} \ No newline at end of file diff --git a/msigdb_hp/advanced/plot_0.png b/msigdb_hp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..53c4d744a96181d925bb628a73ed8850a85cf81e --- /dev/null +++ b/msigdb_hp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:488998e9526f5df9a570e51295f72dc838e1905fa23c0d274a5712d581a46ac0 +size 210879 diff --git a/msigdb_hp/advanced/plot_1.png b/msigdb_hp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..49e4790f86c2a45888de4760d258917ab2932d32 --- /dev/null +++ b/msigdb_hp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8426410597d94a62294f2b5ab1988596148d4a3ed87f0d3b989e6b709f423af +size 219755 diff --git a/msigdb_hp/advanced/plot_2.png b/msigdb_hp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..035628228136c0f7a4b7a140aab9a2f7900dad72 --- /dev/null +++ b/msigdb_hp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64859b978d9b79743c34c6e277c16a9f6a08a2687718dc207b6c71e5f7feefe6 +size 212765 diff --git a/msigdb_hp/advanced/plot_3.png b/msigdb_hp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..bea3b4ea7e07a1be577797a32ace1c0bd323692d --- /dev/null +++ b/msigdb_hp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c96ffa6aa63550df684ecbf1631c717a11a8c96cbe769d5d88b615b6c98ca8f +size 214065 diff --git a/msigdb_hp/advanced/plot_4.png b/msigdb_hp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ddeb3676b806a59dae0966fc5ddcd53db96f8f55 --- /dev/null +++ b/msigdb_hp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fc68829d77fa0a7410d34bc44a15418051a3c57833727e9a08345e16e9cb461 +size 212659 diff --git a/msigdb_hp/advanced/plot_5.png b/msigdb_hp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..e5957fe48593b8c2e54990c264d1fa026f33cc99 --- /dev/null +++ b/msigdb_hp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5eb3919cdd93693c7f5124a3b3f1d2616e9c1cb620f880acb23f544ea92d38a8 +size 212323 diff --git a/msigdb_hp/advanced/plot_6.png b/msigdb_hp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..14fc52a375943dbf104f68bb9bc2f7dc0de0c4d5 --- /dev/null +++ b/msigdb_hp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7311ff1e4a4c810c73e0c2260322b49bc72088844811681b5a0fe475d31321a4 +size 208958 diff --git a/msigdb_hp/advanced/plot_7.png b/msigdb_hp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..4c2eb67b1f5f57d7ff911719fcf17c3675712819 --- /dev/null +++ b/msigdb_hp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b6838b4e93bfd05a3f5eeca96f979355ab8610a83ac2489ddf9313b604cdb31 +size 213666 diff --git a/msigdb_hp/advanced/plot_8.png b/msigdb_hp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..3bbd3c4bc52fb4919e53111184d6e85e37f60680 --- /dev/null +++ b/msigdb_hp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0728a1b2879c2698207ae4a003468fbb4bb387676723ee94c29f7e7cd806b8f7 +size 217822 diff --git a/msigdb_hp/advanced/plot_9.png b/msigdb_hp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..a2df3dde17f89523b9e53ff9b97b7cc2a88d3590 --- /dev/null +++ b/msigdb_hp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cc966cb6a88e9719ea53a017713e0a4a76fac45a6a3c470d1924e9deef1a49c0 +size 193304 diff --git a/msigdb_hp/basic/idx2term.json b/msigdb_hp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2619013e7effb64583dd3bd0816edd3ffe31aadf --- /dev/null +++ b/msigdb_hp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Abnormality of the mitochondrion", "1": "Abnormal circulating protein concentration", "2": "Abnormality of skin pigmentation", "3": "Abnormality of the cerebrospinal fluid", "4": "Hypertrophic cardiomyopathy", "5": "Increased serum lactate", "6": "Abnormal muscle fiber morphology", "7": "Functional motor deficit", "8": "Abnormal myocardium morphology", "9": "Progressive external ophthalmoplegia", "10": "Mania", "11": "Limitation of joint mobility", "12": "Ragged red muscle fibers", "13": "Basal ganglia calcification", "14": "Cognitive impairment", "15": "Limb joint contracture", "16": "Abnormal nervous system electrophysiology", "17": "Muscle weakness", "18": "Central scotoma", "19": "Abnormality of circulating enzyme level", "20": "Depression", "21": "Abnormal corpus striatum morphology", "22": "Abnormal ldl cholesterol concentration", "23": "Abnormality of the thyroid gland", "24": "Abnormality of neuronal migration", "25": "Cystic hygroma", "26": "Muscle abnormality related to mitochondrial dysfunction", "27": "Glucose intolerance", "28": "Abnormal cortical gyration", "29": "Abnormal brainstem mri signal intensity", "30": "Abnormality of the optic nerve", "31": "Abnormal cellular phenotype", "32": "Abnormal sternum morphology", "33": "Mitochondrial myopathy", "34": "Abnormality of lipoprotein cholesterol concentration", "35": "Abnormality of the female genitalia", "36": "Phenotypic variability", "37": "Peripheral neuropathy", "38": "Abnormality of the achilles tendon", "39": "Achilles tendon contracture", "40": "Ptosis", "41": "Gait disturbance", "42": "Abnormal peripheral nervous system morphology", "43": "Weakness due to upper motor neuron dysfunction", "44": "Abnormal circulating lipid concentration", "45": "Abnormal brain lactate level by mrs", "46": "Abnormality of muscle size", "47": "Polyneuropathy", "48": "Abnormality of the nasal tip", "49": "Abnormality of the basal ganglia"} \ No newline at end of file diff --git a/msigdb_hp/basic/plot_0.png b/msigdb_hp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..75306d32e866217243bc015d615d49ee9f69e660 --- /dev/null +++ b/msigdb_hp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7bc835f738d7a1df56875ac76df3957bd6ece97a5f6fe272397fd5022cadc2b4 +size 142048 diff --git a/msigdb_hp/basic/plot_1.png b/msigdb_hp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..a1d85c46d9c4825893f0d94614f8b6551fbd5bb9 --- /dev/null +++ b/msigdb_hp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e63b719d52ac1be5b257a554b074cc63b7d148bf8d915bfecb003edf0785ce68 +size 149715 diff --git a/msigdb_hp/basic/plot_10.png b/msigdb_hp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..1c2666d3ed557cf37372a06085505d29f754543b --- /dev/null +++ b/msigdb_hp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ec44c884a63746e16161a3b3273692f1accb46200eb45ba2e315fadeeb9aba55 +size 126445 diff --git a/msigdb_hp/basic/plot_11.png b/msigdb_hp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..39caf6fc256e87bd36b7548100da7ab2d656f934 --- /dev/null +++ b/msigdb_hp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:530ed3141d645312d6dc2b1cd5327a469eb321fe0bd11fd95fb37fd2e20aadda +size 139383 diff --git a/msigdb_hp/basic/plot_12.png b/msigdb_hp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..f9bb0a3d92bd490152ba736c9599d611ff66a87e --- /dev/null +++ b/msigdb_hp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43465a2f3e6ca0e6393d9dccf195e61bdc889ca2235047b5fe8c6a2203ba943f +size 137006 diff --git a/msigdb_hp/basic/plot_13.png b/msigdb_hp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..d26ac48d8ee1985e0a6a0d439ce3b75033152a79 --- /dev/null +++ b/msigdb_hp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:73e59711d4a51657a184bbb615b54d38fc6072d01c51cd59fffb20bb8dbf5126 +size 134593 diff --git a/msigdb_hp/basic/plot_14.png b/msigdb_hp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..4a909a2e6a10f375645e1c44ee0f1617d4854d6d --- /dev/null +++ b/msigdb_hp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b7632d001fa0342e0f94f03acd92ff9b98a0a236e6b1793b7fb7ef4df1cc0e8 +size 136374 diff --git a/msigdb_hp/basic/plot_15.png b/msigdb_hp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..6ae834406f00e5365cac8ce5a37b86df2e8b40d8 --- /dev/null +++ b/msigdb_hp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:912c04cf224fa6e93d75413655e062ac284ce5095ecffd8750376d91a94ddd9c +size 139322 diff --git a/msigdb_hp/basic/plot_16.png b/msigdb_hp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..50f282e93bbb6ea0126e828ac38ca0685345108f --- /dev/null +++ b/msigdb_hp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c80d92fedfb82da504235ea09d5129d71e323c1b118247e576c8186f1df8b95 +size 148714 diff --git a/msigdb_hp/basic/plot_17.png b/msigdb_hp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..ea2c47ec65bf9676f385a75bea384d0bbd5c1f31 --- /dev/null +++ b/msigdb_hp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4edffa629102d707ca2470d06c187551a8e017d369f98b860ed209e5a0a864c3 +size 138117 diff --git a/msigdb_hp/basic/plot_18.png b/msigdb_hp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..1962f8fdd4c8e26027d67af80f79b41da2dc8779 --- /dev/null +++ b/msigdb_hp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:51a96bc8d237465ffa20bbf88fa886a7b8a330fdea590e459dc10cfb834a5250 +size 131682 diff --git a/msigdb_hp/basic/plot_19.png b/msigdb_hp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..a07e0bcc1ba4f28eaf0d8049b793e484e5b5735c --- /dev/null +++ b/msigdb_hp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90399ccba7e0f5d8f68077894bfe25a921911d8ed5c00dbb79eb0d9d001f5a42 +size 148084 diff --git a/msigdb_hp/basic/plot_2.png b/msigdb_hp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6bd2fbe35246c86e716133cce4249c33950b93d4 --- /dev/null +++ b/msigdb_hp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7133788392f988ed1f3a90dd6c512dae3eb791c06b37f31950e100bec9a3ba2 +size 146992 diff --git a/msigdb_hp/basic/plot_20.png b/msigdb_hp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..423a4e5464b2f6cf6904628f5a62d45ed5ce4e49 --- /dev/null +++ b/msigdb_hp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed9cc84187416a24c656807c333b96935c2999b7e3f972f9e8601e26c5556db1 +size 137665 diff --git a/msigdb_hp/basic/plot_21.png b/msigdb_hp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..84093c68ebc907b733bd5aac4fcae1de7811dd3d --- /dev/null +++ b/msigdb_hp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a067ca910b90206f5c6d8cbbac899e93193ed800dc983df8a169097e1dd06af +size 140839 diff --git a/msigdb_hp/basic/plot_22.png b/msigdb_hp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..fd1eb72aebd71183d4fe2f3c094b79ada6de12b6 --- /dev/null +++ b/msigdb_hp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ccff0aff40c2288009f56883f8eb655241638c3ba7d9df18f5d4323fcb651a7 +size 127966 diff --git a/msigdb_hp/basic/plot_23.png b/msigdb_hp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..cb6cdaadb6da187b688f1a1a4e41196309790014 --- /dev/null +++ b/msigdb_hp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bf9d2ee3b67abf55e7c3a9df17c39c01b59818b8c874bf673c9ff09784737cfb +size 142281 diff --git a/msigdb_hp/basic/plot_24.png b/msigdb_hp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..c0f708d493e240dc7aaae825774681e4961872fa --- /dev/null +++ b/msigdb_hp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd9afcb78f5282257cb1f0ee87158b985d46f7d9bcea36cab64f64e0205a3205 +size 141047 diff --git a/msigdb_hp/basic/plot_25.png b/msigdb_hp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..30304daac6a46520c4ba42165dc46001881b1493 --- /dev/null +++ b/msigdb_hp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:37a27bafef35a0a60431ebba3b626e1cc8d8e790f9364b45d43a717ef192a553 +size 128337 diff --git a/msigdb_hp/basic/plot_26.png b/msigdb_hp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..ad0b60541ae8eab2a0a3167d6b2bdfd6d1ea6168 --- /dev/null +++ b/msigdb_hp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eaa236823104d37ea32ba5fbec288f427c88c8653aabcbd90c4bf33fa6ae2764 +size 140238 diff --git a/msigdb_hp/basic/plot_27.png b/msigdb_hp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..b8627535c94d0dfbbeea735f69371f43f333c24b --- /dev/null +++ b/msigdb_hp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:503b730c92744ef7875e8a49909302eced07e097b3a233a0cfb35b818852407a +size 137924 diff --git a/msigdb_hp/basic/plot_28.png b/msigdb_hp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..1769e9eb87bf82d5ff972ee6dece135a8d904490 --- /dev/null +++ b/msigdb_hp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ebd56f022a8a2299f6fc63f0661a95ac056fb9ef479606fc5dcd6ae771a9b84 +size 140851 diff --git a/msigdb_hp/basic/plot_29.png b/msigdb_hp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..a0b396135e0af6bc3677683c5a40480d08499b07 --- /dev/null +++ b/msigdb_hp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fd1b6c2f5d0a4bc3bac98da6b48a6ebdbbdfc1c20e13dca9001b4c86298b553 +size 138063 diff --git a/msigdb_hp/basic/plot_3.png b/msigdb_hp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..b5443246fcc17c7fc8c63e930c1772596c545db8 --- /dev/null +++ b/msigdb_hp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ea671b788a29c6a9795cb8075b5ec8967a02fe5b25900eeeef447501ebd7326 +size 146120 diff --git a/msigdb_hp/basic/plot_30.png b/msigdb_hp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..b138ccd28455bafdf6fcec1bdb9ecbc9081e7b69 --- /dev/null +++ b/msigdb_hp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9076df0d42c809f819362e869543c49c7844da83d2aaa12f8e4d7707fa6fe35 +size 144101 diff --git a/msigdb_hp/basic/plot_31.png b/msigdb_hp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..62e9773404c08c701eac2efb34eb7e8b05778cf0 --- /dev/null +++ b/msigdb_hp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be5ea4db887947b020a257acc6c2122138086d653f3ffa73bb892c6139922eb0 +size 139117 diff --git a/msigdb_hp/basic/plot_32.png b/msigdb_hp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..48b6c7cddf73d2a49a42d4ad8b0a7ce7d6ee4b88 --- /dev/null +++ b/msigdb_hp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f2e3d701d1c15f8afe14f762595cc287541edef75ff65c4b9849c03767244b2d +size 144740 diff --git a/msigdb_hp/basic/plot_33.png b/msigdb_hp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..1f4889a8ff19df2b7a55ecadbeb5da11af230d9a --- /dev/null +++ b/msigdb_hp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8ebca91ed3f9ca25559b4a1703da4bb81c7d37380fd65e3220b3bd5948100bfb +size 134653 diff --git a/msigdb_hp/basic/plot_34.png b/msigdb_hp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..dc363fbc95ec21ead700162755d61f4949b4bd22 --- /dev/null +++ b/msigdb_hp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d39f7caeaa37ae6fc434bb79da6975d04a46b4c19ab1491fc9b71ce55fe991a4 +size 139619 diff --git a/msigdb_hp/basic/plot_35.png b/msigdb_hp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..c1f6dd2745704998cee1604496551ff2c9e4e865 --- /dev/null +++ b/msigdb_hp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0137508900b3285836df66205589ced2ba5d22aae44a1f69e033636c771e6152 +size 139812 diff --git a/msigdb_hp/basic/plot_36.png b/msigdb_hp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..c8cccce9f0e5a8cd9832c2464d0a9af6a8b46d25 --- /dev/null +++ b/msigdb_hp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b58611f4f9605c7436bf423823070173264c0f7c12df41c532410ffc3f237de0 +size 141146 diff --git a/msigdb_hp/basic/plot_37.png b/msigdb_hp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..8f24f731e6eea8b3be3f2ed9f4df877f7f86c992 --- /dev/null +++ b/msigdb_hp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:572ae026e7a618208a7808bfe3a46db97b220b6f3de73e35917c5387fb8b945b +size 137824 diff --git a/msigdb_hp/basic/plot_38.png b/msigdb_hp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..c29cf10059927a2a1d5ee72c37bda9ea8f5adb1e --- /dev/null +++ b/msigdb_hp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:047532727d9741f60e72f7b0752e24180b19b559e2777aac1e29da20d321dd43 +size 138919 diff --git a/msigdb_hp/basic/plot_39.png b/msigdb_hp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..23c4a55fcf58c67c53ce7ee602c20da09e2b9e59 --- /dev/null +++ b/msigdb_hp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52c3f5f3cdb121e5209813cef52c6ac368806492edc731f8fe58fe4992573fee +size 136573 diff --git a/msigdb_hp/basic/plot_4.png b/msigdb_hp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..8e02ab0fd39d09f888f22ff8294294d5ce12fc3d --- /dev/null +++ b/msigdb_hp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3695dfc3ea126acff2c2e632307ab932ed7bc584af264f345df82718bc57dc65 +size 145739 diff --git a/msigdb_hp/basic/plot_40.png b/msigdb_hp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..4d76cbb0d32adb0b41cab8da2a6e08158954b675 --- /dev/null +++ b/msigdb_hp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0d88bb132a8846ab546f8b96cd8ca76018e68765723160ac52c9977e8d9328f5 +size 132072 diff --git a/msigdb_hp/basic/plot_41.png b/msigdb_hp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..c80937de447da813e16465ecc893078399d888af --- /dev/null +++ b/msigdb_hp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:917aaa896c7a318baad9e01b96b7e6f96f13d55fed9ce9af35dd079d2d725806 +size 137737 diff --git a/msigdb_hp/basic/plot_42.png b/msigdb_hp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..4cf2b16d9e2107f07ad6565bd6ecbe52b5c72c96 --- /dev/null +++ b/msigdb_hp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a937e028e6085d50ba37f4ff01afa72cae6ad8dd7131669ffdcb6bd84e8d2ad +size 149219 diff --git a/msigdb_hp/basic/plot_43.png b/msigdb_hp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..c9bbe3a184f0aa3837d795536dec8fcbf05e39b2 --- /dev/null +++ b/msigdb_hp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ee9365d5ff990f0398b7d3b6bf34b317af0ddd1c48216960cb562fc6fa7a17d +size 146664 diff --git a/msigdb_hp/basic/plot_44.png b/msigdb_hp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..173445f8ec8921c13e2baceaefd7e608b9806cf3 --- /dev/null +++ b/msigdb_hp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a620b2e74f502f3f828b492e6b6e66743a83771980c2b2bd58f4d5599e8d73df +size 141348 diff --git a/msigdb_hp/basic/plot_45.png b/msigdb_hp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..c66ea967c190b3a403ddf597fea295e1a1ac7ece --- /dev/null +++ b/msigdb_hp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f28d0fce9c57c09dfb1833bc6ad9ee35fc4997a55a31e11c91207bd2fab700f +size 127507 diff --git a/msigdb_hp/basic/plot_46.png b/msigdb_hp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..466305431a907827d52c00eb9a2e2cc6c56faddc --- /dev/null +++ b/msigdb_hp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:290059c695269f4094298ef37ed737db5b59757c3ca3ed8af1ccd1b1ec2d0798 +size 140610 diff --git a/msigdb_hp/basic/plot_47.png b/msigdb_hp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..465dec142f829f9245c333cd4352e55232740e8f --- /dev/null +++ b/msigdb_hp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a609d4c426ac7fee689dc987227dd29937a35c5201e09990b401cba80e387e45 +size 127706 diff --git a/msigdb_hp/basic/plot_48.png b/msigdb_hp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..fb88bd36c6909feb56c861be343afabda9585025 --- /dev/null +++ b/msigdb_hp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c7364e4aad90058c020be23477e2715143908de33ecd59eb1ce402e25236bced +size 141215 diff --git a/msigdb_hp/basic/plot_49.png b/msigdb_hp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..550d2954dee2bc02fd2f1f0cc6567fcca4cbbe20 --- /dev/null +++ b/msigdb_hp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a5033f722714cae1d405e3f7ed6f6c8935167bdb5f227a11bd2dcfeb557d59d +size 143232 diff --git a/msigdb_hp/basic/plot_5.png b/msigdb_hp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..0fe84a6c96b40e005f3155156da846ce0a2ec9ab --- /dev/null +++ b/msigdb_hp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bddd7c5bb976def8f9f49ec6a88f526abc65a28b98d04c8b0a47c4a5af4e3961 +size 142095 diff --git a/msigdb_hp/basic/plot_6.png b/msigdb_hp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..0065f1ad3a5881e275157c056726004981d7a9c7 --- /dev/null +++ b/msigdb_hp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3ebbcf73f0a7250477535643a4a1aa6da8f9819f2fd0444230506d21049258c +size 140911 diff --git a/msigdb_hp/basic/plot_7.png b/msigdb_hp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..b87ba508841378d5ec1dd3113d0d01793b973963 --- /dev/null +++ b/msigdb_hp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:34e5960ebcd61c0deb9f27cf49a5996657cc97a2875110a6851d7ada14d82a1e +size 138628 diff --git a/msigdb_hp/basic/plot_8.png b/msigdb_hp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..a2bf0ceb088073df5055b14e81f0b8c45e3cf08e --- /dev/null +++ b/msigdb_hp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0ed2b3a863c08b34855193051645615cd3a4ecdd5bcb8b2546c218eaddc7ce7 +size 145221 diff --git a/msigdb_hp/basic/plot_9.png b/msigdb_hp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..4bb12d6bf0bac5af15b9ea2692d16081b1c1a91f --- /dev/null +++ b/msigdb_hp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92d19710d05d0839ef96ad7415ad90172e4f454c80d04d686afc18a0055d55df +size 132144 diff --git a/msigdb_hp/consensus.joblib b/msigdb_hp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..fa1e18dbc89113e297d2e673d03d5af3a3954c32 --- /dev/null +++ b/msigdb_hp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:400a312d5451ad1b26d075f01cbc6bc7f8f41a90f851b6994de9b779ec1c03db +size 380120 diff --git a/msigdb_hp/df_merge.tsv b/msigdb_hp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..71e1d371555949146fbc13404237e9ebd88a5a4b --- /dev/null +++ b/msigdb_hp/df_merge.tsv @@ -0,0 +1,50 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Abnormality of the mitochondrion 24 79 2.660885139618964 0.0077935538301694 24.216019417475728 91.8883495145631 0.797381253925538 0.4153343301115782 10.704523845407817 8.200885590005743 1.4941762160347407 0.3812617801525748 5.561412999334502e-05 0.000938900775095 0.0008706359135815 1.6637000746656064e-06 2.466049003727128e-07 +Abnormal circulating protein concentration 30 130 2.646555877609825 0.0081316069662145 32.71116504854369 148.9271844660194 0.3300298217826257 0.7446264209348606 9.601606439314072 14.083300681736008 0.6353139637633994 0.3197600075827534 0.0326183931669793 0.2741371023198267 0.1627186649646421 0.0024884143356326 0.002205675175381 +Abnormality of skin pigmentation 27 114 2.532657271394084 0.0113201575235648 26.3373786407767 128.95145631067962 0.1990504083782209 0.7377192576079741 10.52829110144782 14.962820356630305 0.6200550523080489 0.2977060696441045 0.3896213231114779 0.8391723218997238 0.2946258068243917 0.0407152046568232 0.0750025122429805 +Abnormality of the cerebrospinal fluid 30 118 2.481105673070176 0.0130975537678512 33.26456310679612 139.65776699029126 0.6333875809946081 0.5372237787257415 11.267291201647208 15.193792257662585 1.1555525507377646 0.3935007134599857 0.3087431538373553 0.1294501791221148 0.2010885902719557 0.1970930435639763 0.029693288534937 +Basal ganglia cysts 0 6 2.44623800587328 0.0144355670934213 1.5436893203883495 6.509708737864078 0.6375864218957229 0.3423964855972016 1.553428397761971 0.5418441296142611 1.195152711044975 0.2990830010801169 0.0891072447823885 0.0325017468768143 0.0647424502180396 0.1565948204648432 0.2942334307578267 +Abnormal caudate nucleus morphology 4 7 2.4188585646841134 0.0155692925301551 2.8519417475728157 10.133495145631068 0.4630014218675518 0.4635627378613905 1.7037711217888412 1.7774598482419672 0.9891574305728495 0.3131768373752813 0.2443554045423122 1.0 0.1820374447866984 0.0132372029803992 0.0028145739091465 +Fluctuations in consciousness 4 6 2.3812695848813856 0.0172530804925568 2.871359223300971 7.104368932038835 1.0899440920546752 0.2545542015295898 1.680977263462837 1.481694234866534 1.1451509420956862 0.2733842157028129 0.2239007401958742 0.0858288536093336 0.1662183776826317 0.3703176202019055 0.0017429018144962 +Short nail 1 5 2.3584352932862367 0.0183521589494439 1.5946601941747574 4.990291262135922 0.8281151844707718 0.3406921792672602 1.016022432607237 0.7372889940840268 0.9280165491339682 0.2589439848544906 0.0058945182768218 0.04159641685533 0.003087611696091 0.018519525655472 0.0675218785318175 +Hypertrophic cardiomyopathy 22 96 2.3047715866074605 0.0211793692087387 26.796116504854368 107.3495145631068 0.4274787301303976 0.4988726739093555 10.944572821213892 9.196568310864103 1.312724112644841 0.3809066370755179 0.0835252540369047 0.2932939394519023 0.1738229287918353 0.0012548377438148 0.0001218854837124 +Hypertensive crisis 2 5 2.2605955787397813 0.0237843117868201 1.395631067961165 5.060679611650485 0.3087228319795289 0.5364905267937495 1.3169103071557433 1.083283181236265 0.8549837548996176 0.296767935945726 1.0 1.0 1.0 0.003279014583115 0.0225979674873623 +Increased serum lactate 22 87 2.2594376635366147 0.0238561737960334 28.99514563106796 103.9126213592233 0.2156320103365802 0.4835633979758786 13.01418105275692 9.239117761559864 1.4606133548257267 0.3784654233889921 0.0004745772618802 0.1956460215772666 0.0244714513307757 0.0002695489258897 8.806190960704186e-07 +Abnormal muscle fiber morphology 19 61 2.254920322686785 0.0241383304473246 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 5.276814221018997e-05 0.0009131204909424 0.0001426533890264 1.531824572400153e-06 8.223202442636171e-07 +Abnormality of the umbilical cord 2 6 2.249394074282276 0.0244874352817325 2.3276699029126213 7.713592233009709 0.8125665705120105 0.3888135484058521 1.4654305864343329 1.3565768271996297 0.908107514682906 0.2917208108772662 0.2931808389803924 1.0 0.2202973788945578 0.1283849415189241 0.1298078118605267 +Extrapyramidal muscular rigidity 1 5 2.234984595957661 0.0254183600514616 1.614077669902913 5.344660194174757 0.243693314495368 0.4651337602063284 1.1799686822347295 1.006119929092187 1.0315279294489466 0.306042856733725 0.1478851848182938 1.0 0.1084298440104649 0.0323840811666381 0.1125747569923622 +Hemianopia 3 8 2.2302173368567635 0.0257330178484764 2.0776699029126213 7.611650485436893 0.5790308557992101 0.4109966183023263 1.4034584217287485 1.4877037085527185 1.0055409588864108 0.2887898466516661 0.0630468588552109 0.1362745587685063 0.0348321279589049 0.1702739325736192 0.0612536211646263 +Abnormal circulating copper concentration 1 5 2.2150385546843987 0.0267574183048404 1.8422330097087376 5.575242718446602 0.7192357902216235 0.3771156375814327 1.260629702441343 1.0104640332277932 0.9717173289058264 0.2836036003591781 0.1011761938407991 0.0370595951599339 0.073646168181401 0.1768749528600843 0.0542215392640632 +Abnormal labia minora morphology 3 6 2.214970504062357 0.0267620891404429 1.883495145631068 7.293689320388349 0.2965930607959125 0.5453998549506068 1.5108087647888606 1.3719304592549786 0.8241748721821589 0.2957704591591225 1.0 1.0 1.0 0.4559893986318888 0.0308662830144804 +Ascending tubular aorta aneurysm 1 5 2.196317991576538 0.0280691908536288 1.3907766990291262 4.655339805825243 0.9226580213396618 0.308376966533443 1.1148653010373335 0.8882434018008132 0.9888017972034884 0.2648823222498504 0.1703279603954981 1.0 0.1253337423142017 0.0432719236791885 0.1457988469723397 +Large earlobe 0 6 2.191145483924986 0.0284412661776496 1.2475728155339805 7.186893203883495 0.5422037004137905 0.5009307849178536 1.6813855047465125 0.9761839007134184 0.8151491063772431 0.2957012312846327 0.2443554045423122 0.0944323477659319 0.1820374447866984 0.4002719515071794 0.6487121027608701 +Abnormal muscle glycogen content 3 5 2.1842732847309363 0.0289421726351015 1.6966019417475728 4.512135922330097 0.3043369892913118 0.5468257743353838 1.251285981916172 0.9938394221699504 0.8529624348688617 0.30477178619368 0.0073045224575045 1.0 1.0 0.0014512760162947 0.0009118158302113 +Congenital hypothyroidism 1 5 2.1780798876878045 0.0294000896663404 1.233009708737864 4.118932038834951 0.7961562393873879 0.4000524828086099 1.1208862954307102 0.5770117405905518 0.9009690295738 0.3048952861463933 0.1703279603954981 1.0 0.1253337423142017 0.2887519731811417 0.1457988469723397 +Functional motor deficit 37 124 2.1773815940713903 0.0294521078218317 29.844660194174757 142.42233009708738 0.5480906983959746 0.6328805215223481 10.059055989942786 15.366123577335584 0.9036149646030954 0.3745397139529565 0.2115055330152495 0.0926073217778258 0.1353609157777671 0.0071500439243703 0.0017704565545225 +Abnormal placental size 2 5 2.1534446566512084 0.0312837491719513 1.1601941747572817 4.043689320388349 0.90090382190186 0.3404709358270125 0.9944349818715904 0.2044029443827893 0.9631405643658416 0.2828995708650892 0.1011761938407991 1.0 0.073646168181401 0.0146338936924203 0.0053031795330487 +Transposition of the great arteries 1 5 2.138293019717397 0.0324929687408763 1.203883495145631 5.665048543689321 0.7562120366134815 0.4185380653537092 1.1667665326732786 1.0969692349824032 0.827947918729971 0.2809375696957198 0.3816324585246899 1.0 0.2915824887707032 0.2140290435859761 0.5274882304980407 +Bulbar signs 4 11 2.136340285999881 0.0326516874567826 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0666829380567259 0.1403531442218371 0.0369282917904302 0.0407347123090255 0.0179733508374719 +Limited extraocular movements 2 5 2.109580824998077 0.0348944774158703 2.1990291262135924 6.609223300970874 0.2570750514290227 0.5659845824641874 1.6441124820159343 1.202833377738869 0.8489856977549731 0.3050991448868925 0.1703279603954981 1.0 0.1253337423142017 0.2887519731811417 0.0277461310389573 +Hypolipoproteinemia 3 6 2.098985921202344 0.0358181418266889 2.012135922330097 7.419902912621359 -0.2067428439258897 0.2858857288987706 1.2818176948709763 0.8394936004146474 1.4245908115561985 0.2564092064487511 0.1921839078428937 1.0 1.0 0.3225700131084155 0.0062633876942655 +Hypocholesterolemia 4 7 2.0967536185941413 0.0360153913334728 3.2645631067961167 8.048543689320388 1.205673434171466 0.2055905154190861 1.747510449264718 1.0646904903887575 1.232151298114248 0.2464368010987078 0.1591808937815334 1.0 1.0 0.2712176839291556 0.0002457979454447 +Mitochondrial respiratory chain defects 2 5 2.080129825073018 0.0375136266423861 1.8033980582524272 5.177184466019417 1.0048180638921334 0.285673153216041 1.1353491002390874 1.0681459460620504 1.0953831291184488 0.2879410254685434 0.0184946027378239 0.0727733471903131 0.1419203898220533 0.0553069748090555 0.0397387250697101 +Abnormal myocardium morphology 45 149 2.075126563395594 0.0379748064310496 39.25970873786408 168.2597087378641 0.3575832300862268 0.6390291398034755 13.965214340125677 16.3501737739829 0.9922765990658236 0.3661562236284471 0.1061144995038523 0.3182553603760399 0.3721354382290351 0.0012245623106281 1.4944970582672433e-05 +Increased muscle lipid content 2 8 2.072254550943537 0.0382417084935431 2.483009708737864 9.390776699029129 0.3904725741109144 0.5181959742704619 1.7755629956050702 1.1256982207133752 0.8681411855670575 0.2996266757182204 0.0033116660049969 0.1029565435856987 0.1975594178204269 0.0170176746213231 0.0233101974365333 +Abnormal circulating acetylcarnitine concentration 1 6 2.070903259970509 0.0383678374702192 1.7475728155339805 6.606796116504855 1.2739071869107932 0.2367430781797907 1.3686393682873708 0.7076231425197869 0.8717674578101685 0.2465605045996027 0.0105293638672671 0.0550816697898294 0.1084298440104649 0.0323840811666381 0.1125747569923622 +Abnormal endocrine physiology 1 6 2.0169610034773577 0.0436995830409587 1.5072815533980584 4.864077669902913 0.5780846062951066 0.4240047630925435 1.154327185344247 0.5176223402938378 0.9656380632011404 0.3051266181071854 0.1364388664089949 1.0 0.0998570540504815 0.2348471946143729 0.0968157430558884 +Progressive sensorineural hearing impairment 4 10 2.0168697321527764 0.0437091094849262 3.1092233009708736 10.177184466019416 0.6816533912969537 0.4125027093829873 1.9409267075593708 1.400472817159746 0.9707665840558262 0.3067183945172701 0.0459772463951516 0.1155957163384056 0.0251008323038497 0.0237046415332288 0.0074494564855197 +Progressive external ophthalmoplegia 5 8 2.012900335090824 0.0441251153235549 3.378640776699029 10.228155339805824 0.6986896615619974 0.3934319655103426 1.8174798771838792 2.269764004486748 0.9524665755192452 0.2940766219203315 0.3025633942128303 0.1197698958477507 0.2277340705622599 0.0262058522408301 0.008785557350241 +Endocarditis 2 5 2.010530100167306 0.0443751137579071 1.6699029126213591 5.055825242718447 1.0315066990472646 0.3137673633075574 1.128951309195931 0.7031759081548564 0.9300019606367588 0.2935479974969262 1.0 1.0 1.0 0.2532529321952443 0.018020673376298 +Mania 8 14 2.0093128044866253 0.0445039708187982 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.3388733146593771 0.1362745587685063 0.2567853086841904 8.049397313815918e-05 1.0771282196058985e-05 +Abnormality of circulating adrenocorticotropin level 3 9 2.0046353857272226 0.0450020407981841 2.6067961165048543 8.526699029126213 0.4678017709762634 0.488215339376942 1.5566183247401906 1.8673915603090907 0.8467951338817273 0.2872828179813482 0.3209592115478971 1.0 0.2423974925429197 0.1532325517723639 0.0498364179528963 +Macrogyria 2 5 1.9960967401006904 0.0459233938102314 1.5024271844660195 5.648058252427185 0.9880312678764684 0.314713035809367 1.057793055191099 0.9137148736849272 0.850980571286911 0.2493075505833739 0.2543811559285687 0.0987043131013681 0.1898352204968973 0.0150601402708497 0.088385561156941 +Limitation of joint mobility 24 85 1.9927770834052172 0.0462858622358539 21.060679611650485 97.9368932038835 0.3085934150476662 0.6495028096480517 7.742751544501191 10.216391648179064 0.8329388631334591 0.334643383369233 0.481881993932746 0.7250699228374891 0.4762657143534315 0.2023140819149558 0.0062019621034948 +Diffuse white matter abnormalities 3 5 1.9913037394703588 0.0464475046050605 2.9514563106796117 8.87135922330097 0.5952845668725205 0.3852144131329246 1.9847899342355348 1.8774220853320651 1.0510828155917642 0.2960660984241839 1.0 1.0 1.0 0.1283849415189241 0.0351238878380088 +Ragged red muscle fibers 7 16 1.9909672624896708 0.0464844864867408 5.233009708737864 17.730582524271846 1.450228655394427 0.2143723456093393 2.356374883616516 2.3878203593303375 1.2019998086948689 0.268108115907532 0.0001515131202945 0.0007945346802546 0.0004905065400264 0.0003037206293647 7.999759770652472e-05 +Degeneration of the striatum 1 5 1.9899211829678016 0.046599618492586 1.8932038834951457 3.9466019417475726 -0.2208237751780239 0.6131195486980414 1.2476200361279972 0.7050876877203788 0.7706398530337517 0.2901342554773621 1.0 1.0 1.0 0.018519525655472 0.0675218785318175 +Vasculitis 3 6 1.9811969870591888 0.0475691869876113 2.361650485436894 8.87378640776699 0.3757790321326342 0.558567904308775 1.71735436464403 1.649828538608041 0.796059568569427 0.3023411355445772 1.0 1.0 1.0 0.1617118829485157 0.0553856285019619 +Basal ganglia calcification 5 8 1.9802212664387184 0.0476786712412837 2.2063106796116503 7.344660194174757 0.7754851929382625 0.4050161590811829 1.490637115556397 1.3943873732460157 0.8989440633592655 0.3080162794814239 0.3388733146593771 0.1362745587685063 0.2567853086841904 0.0375621633755105 0.0612536211646263 +Decreased circulating cortisol level 2 8 1.9790240760651672 0.0478132956302317 2.5606796116504853 8.04368932038835 0.1947165538163931 0.4986395179547063 1.6919878365694236 1.428908871717281 0.9516774885421178 0.2953741886368603 0.2543811559285687 1.0 0.1898352204968973 0.4147125777305785 0.088385561156941 +Poor wound healing 1 6 1.973146400537916 0.0484788850799351 1.779126213592233 5.665048543689321 0.5228882363471196 0.4337271195964888 1.28178092640413 0.7564876346199129 0.966090262178579 0.3006630201307761 0.1591808937815334 0.0595353304203936 0.1169218221283287 0.0376759114543004 0.1289341732663725 +Cognitive impairment 38 151 1.9709834782965077 0.048725765631747 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 0.0362815433178721 0.1605759209977755 0.0643029549566581 0.0059289881442161 6.999987962051208e-05 +Hip pain 1 5 1.9647842969354623 0.0494392084372456 1.424757281553398 5.0 0.859024349165147 0.3344821452752615 1.281560293450117 0.0 0.9235596175512634 0.2706747767807553 0.0891072447823885 1.0 0.0647424502180396 0.1565948204648432 0.0419919493306108 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..1ba87d871d5793c49d2777f439e06d81e46ca3b8 --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 4507, + "title": "Average number of proteins per term", + "value": 21.251608608830708 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fdc713cdee113f48f3e27796b0c3bcfff4fe1d31 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e54427049d39c5f866409a1238cd70659ee0c426 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1458 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Social and occupational deterioration 0.9480427046263388 2.775900783917145 0.0055049004508738 0.9999999999843278 0.1836099134524617 2 Q9BQE5 1 +Negativism 0.9480427046263388 2.775900783917145 0.0055049004508738 0.9999999999843278 0.1836099134524617 2 Q9BQE5 1 +Chronic axonal neuropathy 0.9341637010676208 2.719608413344241 0.006535926574364 0.999999999999854 0.1836099134524617 2 O15269 1 +Abnormal mitochondrial number 0.920640569395018 2.664379016747072 0.0077130605039907 0.9999999999999992 0.1836099134524617 2 P46976 1 +Abnormality of the mitochondrion 0.5356648612043167 2.660885139618964 0.0077935538301694 0.9999999999999996 0.1836099134524617 79 O75880,P13073,P12235,Q70HW3,O43676,P03886,P23786,P00403,Q5JPH6,Q9Y2R0,Q9Y4W6,Q9UBX3,Q7KZN9,O96000,P46976,Q9Y6M9,Q9BQP7,O43772,O75306,P35637,Q00325,Q3ZCQ8,O75648,Q96CU9 24 +Axial dystonia 0.9163701067615708 2.6468596001659543 0.0081243075645336 1.0 0.1836099134524617 2 Q99720 1 +Retrocollis 0.9163701067615708 2.6468596001659543 0.0081243075645336 1.0 0.1836099134524617 2 Q99720 1 +Abnormal circulating protein concentration 0.4347539425986472 2.6465558776098255 0.0081316069662145 1.0 0.1836099134524617 130 P50402,P12235,Q14C86,Q08J23,Q8N511,P23786,Q96BR5,P36551,Q9Y487,O14979,O95831,Q8NFH4,P42167,Q9BPX6,P53985,P47985,P42166,P15260,Q9Y4P3,Q8N1F7,Q9UJS0,Q9BQP7,O43772,O95470,Q9BT22,Q9Y285,Q5JRX3,O75648,Q15120,Q9BUK6 30 +Severe lactic acidosis 0.9140442033258116 2.6343187474802563 0.0084306302281973 1.0 0.1836099134524617 3 Q70HW3 1 +Neck flexor weakness 0.9082997452872212 2.6079631800604743 0.0091082751120588 1.0 0.1836099134524617 4 Q99720,P46976 2 +Increased muscle glycogen content 0.9030141026822348 2.5886282989492972 0.0096359043874361 1.0 0.1836099134524617 3 O75648 1 +Short umbilical cord 0.9010998434392242 2.5806727726657335 0.0098608000397484 1.0 0.1836099134524617 3 O75844 1 +Psoriasiform dermatitis 0.8985404058383811 2.570023878544178 0.010169150529051 1.0 0.1836099134524617 3 P01889,Q15800 2 +Upper airway obstruction 0.8987479068152169 2.5681107971588677 0.0102254466999263 1.0 0.1836099134524617 4 Q96HY6,O75844 2 +Posterior polar cataract 0.893594306049827 2.552780704300828 0.0106866757885653 1.0 0.1864646007203726 2 P08670 1 +Abnormality of skin pigmentation 0.4365063954307188 2.5326572713940836 0.0113201575235648 1.0 0.1918043231530331 114 Q9NZJ7,Q06136,Q08J23,P49327,P03886,P21964,P36551,Q96AY3,P00403,Q8IZA0,P53992,P40818,Q13423,Q7LGA3,Q6PGP7,P07437,P16615,P51648,Q06124,P11802,P42858,O75312,O75844,Q02750,Q9UJX6,O75648,Q92889 27 +Polar cataract 0.8878604485582041 2.525439236083862 0.0115553762668274 1.0 0.1921539545705401 3 P08670,Q9Y287 2 +Lymphangioma 0.8843416370106835 2.5142502793184582 0.0119285747180164 1.0 0.1921539545705401 2 P48735 1 +Visceral angiomatosis 0.8843416370106835 2.5142502793184582 0.0119285747180164 1.0 0.1921539545705401 2 P48735 1 +Hemangiomatosis 0.8843416370106835 2.5142502793184582 0.0119285747180164 1.0 0.1921539545705401 2 P48735 1 +Chondrosarcoma 0.8846564613741604 2.512016782657568 0.0120043379664391 1.0 0.1921539545705401 3 P48735,Q92804 2 +Abnormality of hand joint mobility 0.8814946619217094 2.5023584255273335 0.0123368956053726 1.0 0.1921539545705401 2 P51812 1 +Hyperextensibility of the finger joints 0.8814946619217094 2.5023584255273335 0.0123368956053726 1.0 0.1921539545705401 2 P51812 1 +Elevated circulating long chain fatty acid concentration 0.8786476868327512 2.49044943518263 0.0127581648469781 1.0 0.1921539545705401 2 P23786 1 +Abnormality of the cerebrospinal fluid 0.4297727283754143 2.481105673070176 0.0130975537678512 1.0 0.1921539545705401 118 P13073,O43676,Q9NZJ7,Q08J23,O43819,O96028,P03886,P21964,P23786,Q15392,Q92947,P00403,P53992,Q969G3,Q9P0J0,O95831,Q7KZN9,P08236,Q9Y3Z3,Q9HC21,O96000,O75312,P40855,Q8NCW5,Q9Y6M9,Q02750,O75306,Q96CU9,P16435,Q92889 30 +Reduced factor xiii activity 0.8750889679715355 2.4755390697592525 0.0133035205134228 1.0 0.1921539545705401 2 Q06124 1 +Reduced factor xii activity 0.8750889679715355 2.4755390697592525 0.0133035205134228 1.0 0.1921539545705401 2 Q06124 1 +Amegakaryocytic thrombocytopenia 0.8750889679715355 2.4755390697592525 0.0133035205134228 1.0 0.1921539545705401 2 Q06124 1 +Centrocecal scotoma 0.8725525097899746 2.461112998047683 0.0138506735214674 1.0 0.19262050551255 3 P03886,O60313 2 +Small placenta 0.8730893908651316 2.4600988712984164 0.0138898744822673 1.0 0.19262050551255 4 O75844 1 +Abnormality of krebs cycle metabolism 0.8718752924384536 2.4549532009855453 0.0140902930507531 1.0 0.1942047424457018 4 P03886 1 +Ketotic hypoglycemia 0.8658517180684414 2.432798322087766 0.0149826435460354 1.0 0.1989281475417908 3 Q13423 1 +Abnormal caudate nucleus morphology 0.8645842174624226 2.4188585646841134 0.0155692925301551 1.0 0.2006266347133107 7 Q9BVA1,O43819,P42858,Q92947 4 +Fasting hypoglycemia 0.8618014932972943 2.415637334203645 0.0157076977307508 1.0 0.2006266347133107 3 O43772 1 +Widened cerebral subarachnoid space 0.8589410382327587 2.403496332146557 0.0162391299199715 1.0 0.2006266347133107 3 P03886 1 +Smooth muscle antibody positivity 0.8576512455516051 2.4020897007583204 0.0163017104957905 1.0 0.2006266347133107 2 Q96J02 1 +Decreased ldl cholesterol concentration 0.8583125667497354 2.400826484335425 0.0163580910853802 1.0 0.2006266347133107 3 P37268,Q15800 2 +Neuroinflammation 0.8579565681737281 2.3993137703711667 0.0164258327511008 1.0 0.2006266347133107 3 Q9NZ08,P01889 2 +Pleuritis 0.8579565681737281 2.3993137703711667 0.0164258327511008 1.0 0.2006266347133107 3 Q9NZ08,P01889 2 +Pulmonary embolism 0.8579565681737281 2.3993137703711667 0.0164258327511008 1.0 0.2006266347133107 3 Q9NZ08,P01889 2 +Orchitis 0.8579565681737281 2.3993137703711667 0.0164258327511008 1.0 0.2006266347133107 3 Q9NZ08,P01889 2 +Fluctuations in consciousness 0.8559194964377683 2.3812695848813856 0.0172530804925568 1.0 0.2045346624127311 6 P00403,P03886,O43819,Q9UJS0 4 +Abnormal circulating long chain fatty acid concentration 0.8526736197878625 2.3768335203149435 0.0174619672399731 1.0 0.2045346624127311 3 P23786 1 +Mitochondrial inheritance 0.8516078196919696 2.3685873854056547 0.0178561616412293 1.0 0.2045346624127311 4 O75648,P03886 2 +Short nail 0.8499983083388581 2.3584352932862367 0.0183521589494439 1.0 0.2051911808444502 5 Q9Y487 1 +Lacticaciduria 0.848252697762357 2.354205043230465 0.0185623687451266 1.0 0.2051911808444502 4 P03886 1 +Stuttering 0.8456433992843502 2.3468255083448657 0.0189341195594168 1.0 0.2051911808444502 3 P03886 1 +Limb fasciculations 0.8441123902962598 2.336423466971884 0.0194691820744115 1.0 0.2066134811091467 4 P04792 1 +Retinal thinning 0.8391459074733227 2.323435078577787 0.0201557914970045 1.0 0.2074416279156899 2 P51648 1 +Oromandibular dystonia 0.8398478063110348 2.322007765799201 0.0202325174788564 1.0 0.2077174402669842 3 Q99720 1 +Pericarditis 0.8392480817388489 2.315485340663754 0.0205863859010013 1.0 0.2099159304430162 4 Q9NZ08,P01889 2 +Hypertrophic cardiomyopathy 0.4285936900565733 2.3047715866074605 0.0211793692087387 1.0 0.2142532726324181 96 P50402,O43676,O43819,P03886,P01889,Q5JTZ9,P00403,Q13423,O60313,Q7KZN9,P47985,Q06124,Q9Y3Z3,Q9Y4P3,O96000,Q9Y6M9,Q02750,Q9NVI7,O75306,Q9H061,Q00325,Q96CU9 22 +Mixed demyelinating and axonal polyneuropathy 0.8341046635813637 2.297343582439803 0.0215991774342043 1.0 0.2168095605700647 3 P00403,P03886 2 +Ankylosis 0.8338086719008855 2.292011385791139 0.0219049861773235 1.0 0.2179748448109102 4 O75844 1 +Abnormal response to endocrine stimulation test 0.8324789771084538 2.2862633533687897 0.0222388564204965 1.0 0.219803784840302 4 Q13423 1 +Aplasia hypoplasia of the patella 0.832020963606477 2.284282561621635 0.0223549300827019 1.0 0.2204675489775441 4 Q9Y619 1 +Elevated diastolic blood pressure 0.8270462633451947 2.2716117587089655 0.0231099700464685 1.0 0.2230334796561748 2 P35611 1 +Elevated systolic blood pressure 0.8270462633451947 2.2716117587089655 0.0231099700464685 1.0 0.2230334796561748 2 P35611 1 +Elevated mean arterial pressure 0.8270462633451947 2.2716117587089655 0.0231099700464685 1.0 0.2230334796561748 2 P35611 1 +Abnormal circulating citrulline concentration 0.8280220212414372 2.2669689708377874 0.0233921213018177 1.0 0.2247937968172553 4 P03886,Q9Y619 2 +Concentric hypertrophic cardiomyopathy 0.8262470332598331 2.26348407049386 0.0236058654798057 1.0 0.2258845768948711 3 P03886 1 +Hypertensive crisis 0.8274089585194184 2.2605955787397813 0.0237843117868201 1.0 0.2271099432694883 5 P01889,P21964 2 +Increased serum lactate 0.4267630178072077 2.2594376635366147 0.0238561737960334 1.0 0.22731453551527 87 O75880,P13073,Q70HW3,O43819,P03886,Q9BWD1,Q5JTZ9,P00403,Q5JPH6,O95831,Q9UBX3,Q7KZN9,Q9Y6M9,O14949,Q9NVI7,O75306,Q00325,Q5JRX3,Q3ZCQ8,O75648,Q96CU9,Q6P4A7 22 +Abnormal muscle fiber morphology 0.6386807424870927 2.2549203226867855 0.0241383304473246 1.0 0.2291234563062449 61 P50402,Q70HW3,O43676,P03886,P23786,Q9H2D1,P00403,Q5JPH6,O14979,O95831,Q9BPX6,O60313,P51114,Q99720,P46976,Q9BQP7,P35637,O75648,Q9BUK6 19 +Abnormality of the umbilical cord 0.8255852515913832 2.249394074282276 0.0244874352817325 1.0 0.2313728947898715 6 O75844,O43175 2 +Large placenta 0.8204766932961252 2.2385346915377644 0.0251862077324638 1.0 0.2327941549697511 3 O75844 1 +Stroke like episode 0.821309600418109 2.2378299042938496 0.0252321495016156 1.0 0.2327941549697511 4 O76024,P03886 2 +Thin clavicles 0.8201206947201194 2.236993115109856 0.0252867900253364 1.0 0.2327941549697511 3 O75844 1 +Bull s eye maculopathy 0.8188612099644274 2.236377559510168 0.0253270498206297 1.0 0.2327941549697511 2 Q8NHS3 1 +Extrapyramidal muscular rigidity 0.8215375699350778 2.234984595957661 0.0254183600514616 1.0 0.2328466438047517 5 Q9BPX6 1 +Hemianopia 0.8213937978872217 2.2302173368567635 0.0257330178484764 1.0 0.2331051779959875 8 P00403,Q9BVA1,P03886 3 +Hypopigmentation of the fundus 0.8176633544216354 2.2263447241480847 0.0259910999162424 1.0 0.2331051779959875 3 Q9Y619 1 +Generalized lymphadenopathy 0.8160142348754602 2.224088685547017 0.0261424779913974 1.0 0.2331051779959875 2 P15260 1 +Depletion of mitochondrial dna in muscle tissue 0.8169233331473313 2.2187364910360423 0.0265046569117157 1.0 0.2333012297020822 4 Q9UBX3 1 +Synostosis of metacarpals metatarsals 0.8145907473309706 2.2179377697596245 0.0265590757825426 1.0 0.2333012297020822 2 P16435 1 +Maturity onset diabetes of the young 0.8142348754448412 2.21639936617969 0.0266641630712085 1.0 0.2333012297020822 2 P61457 1 +Abnormal circulating copper concentration 0.8169766605586285 2.2150385546843987 0.0267574183048404 1.0 0.2333012297020822 5 Q9Y487 1 +Abnormal labia minora morphology 0.8177418694130618 2.214970504062357 0.0267620891404429 1.0 0.2333012297020822 6 Q15042,Q9Y619,P16435 3 +Lambdoidal craniosynostosis 0.8141990130482207 2.211310749668113 0.0270143254600594 1.0 0.2347544975078283 3 P16435 1 +Corneal erosion 0.8120990217471953 2.1976885606318435 0.0279713072993346 1.0 0.2373002287434228 4 P51648 1 +Ascending tubular aorta aneurysm 0.8127052737157905 2.196317991576538 0.0280691908536288 1.0 0.2373002287434228 5 O75844 1 +Nonketotic hypoglycemia 0.8117557645825202 2.196189065132841 0.0280784137202945 1.0 0.2373002287434228 4 P23786 1 +Abnormal muscle glycogen content 0.8099618162332605 2.1842732847309363 0.0289421726351015 1.0 0.2420081114404504 5 O75648,P46976,Q9BUK6 3 +Cerebral hamartoma 0.8073597267667186 2.181555447581776 0.0291423580313505 1.0 0.2432307549024018 3 Q92947 1 +Congenital hypothyroidism 0.8085525626229164 2.1780798876878045 0.0294000896663404 1.0 0.2436069198186779 5 Q13423 1 +Functional motor deficit 0.4037568056380985 2.1773815940713903 0.0294521078218317 1.0 0.2436069198186779 124 P12235,Q07021,Q9NZJ7,O43819,P03886,P23786,Q15041,Q9H2D1,Q92947,P00403,Q9NXN4,Q69YN2,Q9Y2R0,P61978,P31483,O00429,Q969G3,P13807,P04792,Q9BPX6,O43292,Q15813,Q9Y3Z3,Q9HC21,P42858,Q9Y6X9,Q99720,Q8TD16,P46976,Q9BQP7,Q15067,Q9Y285,P35637,Q15120,Q53H12,Q9BUK6,Q92889 37 +Tritanomaly 0.8035587188612225 2.1701219262447276 0.0299976105590813 1.0 0.2436069198186779 2 O60313 1 +Anomalous trichromacy 0.8035587188612225 2.1701219262447276 0.0299976105590813 1.0 0.2436069198186779 2 O60313 1 +Temporal optic disc pallor 0.8035587188612225 2.1701219262447276 0.0299976105590813 1.0 0.2436069198186779 2 O60313 1 +Morning glory anomaly 0.8035587188612225 2.1701219262447276 0.0299976105590813 1.0 0.2436069198186779 2 O60313 1 +Hydranencephaly 0.8032028469751006 2.168575172441935 0.0301149517843528 1.0 0.2436069198186779 2 O43175 1 +Hepatic cysts 0.803603594562402 2.160502682751791 0.0307337761505217 1.0 0.2438384346886163 4 Q7Z4L5,Q9UGP8 2 +Abnormal placental size 0.8029566148775578 2.1534446566512084 0.0312837491719513 1.0 0.244815184655672 5 O75844,O43175 2 +Transposition of the great arteries 0.7995224440376099 2.138293019717397 0.0324929687408763 1.0 0.249481788952521 5 O75844 1 +Bulbar signs 0.7999422019256504 2.136340285999881 0.0326516874567826 1.0 0.2502740737546244 11 Q99720,P03886,P35637,Q9NZJ7 4 +Exostoses 0.7970085470085352 2.1315286950950156 0.0330456110356685 1.0 0.2523518585554822 4 P48735,Q06124,O75874 3 +Abnormality of circulating leptin level 0.7965883280481731 2.129679406048498 0.0331980903413797 1.0 0.2523518585554822 4 O75844 1 +Hypoplastic labia minora 0.7957712143631037 2.126082396177225 0.0334963994340189 1.0 0.2523518585554822 4 Q9Y619 1 +Clitoral hypoplasia 0.7957712143631037 2.126082396177225 0.0334963994340189 1.0 0.2523518585554822 4 Q9Y619 1 +Abnormality of the distal phalanges of the toes 0.7924265452391179 2.111344046690444 0.0347427506712902 1.0 0.2568623238294691 4 O75844 1 +Limited extraocular movements 0.7930303532234476 2.109580824998077 0.0348944774158703 1.0 0.2568623238294691 5 Q9BVA1,O43819 2 +Protrusio acetabuli 0.790249423362746 2.1066782438516416 0.0351454793036316 1.0 0.2568623238294691 3 Q96AY3 1 +Hypolipoproteinemia 0.7915346041665907 2.098985921202344 0.0358181418266889 1.0 0.2589426310611402 6 P37268,Q9UJS0,Q15800 3 +Absent brainstem auditory responses 0.7884150650862507 2.0986139756038735 0.0358509433730089 1.0 0.2589426310611402 3 O60313 1 +Hypocholesterolemia 0.7913463168090408 2.0967536185941413 0.0360153913334728 1.0 0.2592993110862016 7 P37268,Q9NVI7,Q15800,Q9NZJ7 4 +Recurrent pancreatitis 0.787135363645215 2.092983900751189 0.036350591722275 1.0 0.2609381692695122 3 P03886 1 +Mitochondrial respiratory chain defects 0.7863922246922344 2.080129825073018 0.0375136266423861 1.0 0.2679459830067103 5 P03886,O75648 2 +Abnormal myocardium morphology 0.3803156910492792 2.075126563395594 0.0379748064310496 1.0 0.2699565498182032 149 P50402,P12235,Q07021,O43676,O43819,P49327,P03886,O76024,P23786,P01889,Q5JTZ9,P22626,P00403,P13807,Q9P0J0,P42167,P40818,Q13423,Q9NZ08,O60313,Q7KZN9,P47985,P08236,Q06124,P42166,Q9Y3Z3,Q9Y4P3,O96000,P40855,P54802,P46976,Q9Y6M9,Q9BQP7,Q02750,Q9NVI7,O43772,Q9BT22,O75306,Q9H061,Q00325,P48735,Q53H12,Q96CU9,Q92889,Q9Y375 45 +Increased muscle lipid content 0.7860903493327226 2.0722545509435375 0.0382417084935431 1.0 0.2705735952596529 8 O75648,P23786 2 +Abnormal circulating acetylcarnitine concentration 0.7852388362466531 2.0709032599705095 0.0383678374702192 1.0 0.2706745817915278 6 P23786 1 +Abnormality of the fetal cardiovascular system 0.782002675452727 2.0652588870967516 0.0388985113712891 1.0 0.2709669099697069 4 P47985 1 +Increased total bilirubin 0.779389115113352 2.0536680481125527 0.0400078310751232 1.0 0.2736431208336217 4 P23786 1 +Multiple suture craniosynostosis 0.7782956878004921 2.048814560898149 0.0404802513913638 1.0 0.2755959109076686 4 P21964 1 +Tricuspid atresia 0.7782956878004921 2.048814560898149 0.0404802513913638 1.0 0.2755959109076686 4 P21964 1 +Increased circulating acth level 0.7760032262550944 2.043862448732568 0.040967137742629 1.0 0.278275971309098 3 P40818 1 +Abnormal endocrine physiology 0.7731982578263681 2.0169610034773577 0.0436995830409587 1.0 0.2883093725968895 6 Q13423 1 +Progressive sensorineural hearing impairment 0.774003852109033 2.0168697321527764 0.0437091094849262 1.0 0.2883093725968895 10 O76024,P03886,O60313,O60443 4 +Agenesis of cerebellar vermis 0.7679715302491241 2.0141247356878105 0.0439964391240204 1.0 0.2886345722444832 2 O43924 1 +Progressive external ophthalmoplegia 0.77297871295161 2.0129003350908237 0.0441251153235549 1.0 0.2890579865745086 8 Q9BQP7,P00403,P12235,P03886,O60313 5 +Endocarditis 0.7707875384915854 2.010530100167306 0.0443751137579071 1.0 0.2894336290982453 5 Q9NZ08,P01889 2 +Mania 0.7711314889159336 2.0093128044866253 0.0445039708187982 1.0 0.2898546191912189 14 P00403,P16615,P53992,Q9UJS0,P03886,P21964,P40818,P51812 8 +Abnormality of circulating adrenocorticotropin level 0.7713143558588527 2.0046353857272226 0.0450020407981841 1.0 0.2914140774100804 9 Q13423,P16435,P40818 3 +Macrogyria 0.7675657660876805 1.9960967401006904 0.0459233938102314 1.0 0.2953356352748095 5 O14936,Q15392 2 +Limitation of joint mobility 0.4136361033361416 1.9927770834052176 0.0462858622358539 1.0 0.2953356352748095 85 P50402,O76024,P23786,P01889,Q96AY3,Q15042,P54886,O14979,Q7LGA3,P51648,Q06124,O75874,P08236,Q9HC21,Q9Y4P3,Q8TD16,P54802,O75844,Q9BT22,Q9UJX6,P48735,Q96J02,P37268,P16435 24 +Neuronal loss in basal ganglia 0.7656045491524418 1.992298341437228 0.0463383335787683 1.0 0.2953356352748095 4 O43819,P42858 2 +Diffuse white matter abnormalities 0.7664969532019833 1.9913037394703588 0.0464475046050605 1.0 0.2953356352748095 5 Q3ZCQ8,O43819,O14936 3 +Ragged red muscle fibers 0.7658860229413749 1.9909672624896708 0.0464844864867408 1.0 0.2953356352748095 16 Q9BQP7,P00403,Q70HW3,P03886,O75648,O95831,Q9H2D1 7 +Blurred vision 0.7652170000597209 1.9905672316425764 0.0465284857642258 1.0 0.2953356352748095 4 O75306,P03886 2 +Degeneration of the striatum 0.7661887491089916 1.9899211829678016 0.046599618492586 1.0 0.2953356352748095 5 Q9Y3Z3 1 +Night sweats 0.7637280390671914 1.9893971400914767 0.0466573850720049 1.0 0.2953356352748095 3 P15260 1 +Unconjugated hyperbilirubinemia 0.7630887219425326 1.9865519241249463 0.0469720733412919 1.0 0.2958718740061062 3 O14936 1 +Tongue nodules 0.761209964412826 1.9841866200791192 0.047235039569232 1.0 0.2958718740061062 2 O43924 1 +Vasculitis 0.7652526123690553 1.9811969870591888 0.0475691869876113 1.0 0.2958718740061062 6 Q9Y3Z3,P01889,Q9NZ08 3 +Basal ganglia calcification 0.7657940612013932 1.9802212664387184 0.0476786712412837 1.0 0.2958718740061062 8 P00403,Q9Y3Z3,Q92889,P03886,O60313 5 +Decreased circulating cortisol level 0.7655313076840811 1.9790240760651672 0.0478132956302317 1.0 0.2958718740061062 8 Q13423,P16435 2 +Talipes valgus 0.7606332209072605 1.9756161450419 0.0481982686655668 1.0 0.2958718740061062 3 P49589 1 +Poor wound healing 0.7634680519247408 1.973146400537916 0.0484788850799351 1.0 0.2958718740061062 6 O15269 1 +Distal sensory loss of all modalities 0.7608508787474626 1.9710431300177067 0.0487189427295167 1.0 0.2958718740061062 4 O15269 1 +Cognitive impairment 0.3734888450519395 1.9709834782965072 0.048725765631747 1.0 0.2958718740061062 151 Q03164,P12235,Q9NZJ7,O43819,O15118,Q9BQE5,P03886,P21964,O76024,P49327,Q9Y619,P01889,Q5JTZ9,P22626,Q92947,Q9Y487,P00403,Q9NXN4,Q9Y2R0,Q9Y4W6,Q9Y287,Q969G3,O95831,Q9NZ08,O60313,Q9BVA1,P42858,Q9Y263,P40855,Q8NHS3,Q99720,Q9UJS0,O75306,O95470,Q13217,P04080,P35637,Q6DKK2 38 +Hashimoto thyroiditis 0.7580071174377379 1.9699726296835909 0.0488415074906831 1.0 0.2958718740061062 2 Q96J02 1 +Follicular thyroid carcinoma 0.7580071174377232 1.969972629683525 0.0488415074906907 1.0 0.2958718740061062 2 P21912 1 +Conjunctival hamartoma 0.7580071174377232 1.969972629683525 0.0488415074906907 1.0 0.2958718740061062 2 P21912 1 +Choking episodes 0.7572953736654969 1.9668111167125588 0.0492049904954929 1.0 0.2968766963362609 2 P42858 1 +Staring gaze 0.7572953736654969 1.9668111167125588 0.0492049904954929 1.0 0.2968766963362609 2 P42858 1 +Hip pain 0.7605927883433012 1.9647842969354623 0.0494392084372456 1.0 0.2970966832355551 5 O75844 1 +Spinal deformities 0.7575649697401314 1.9619340370042584 0.0497701644509607 1.0 0.2978939325105975 3 Q9BQP7,Q8TB36 2 +Arterial thrombosis 0.7588896369633754 1.9571209460671088 0.0503332503310045 1.0 0.3004661711812417 5 Q9NZ08,P01889 2 +Deep plantar creases 0.7586104153091666 1.9558640147949151 0.0504811754142848 1.0 0.3006416829868618 5 Q9Y487 1 +Hypothalamic hamartoma 0.7548042704626485 1.955737688410003 0.050496062574008 1.0 0.3006416829868618 2 O43924 1 +Retinal telangiectasia 0.7579871864712976 1.953057938317755 0.0508127302567518 1.0 0.3013328621936584 5 P03886 1 +Limb joint contracture 0.4008533467127836 1.9521545761686667 0.0509198552880558 1.0 0.3014192595077276 87 P50402,Q08J23,P23786,Q9Y619,Q86XL3,Q15392,Q96AY3,Q8IZA0,Q15042,P54886,O60313,Q7LGA3,Q9HC21,Q9Y6X9,Q99720,Q8TD16,O75844,O43175,P42892,P35637,Q9UJX6,P37268,P16435,Q92889 24 +Abnormal nervous system electrophysiology 0.3717621249659107 1.9501047672706553 0.051163633169351 1.0 0.3022208318404522 164 P13073,Q9NZJ7,Q08J23,O96028,Q9BQE5,P03886,P21964,Q9Y619,Q5JTZ9,P00403,O15269,Q9NZ01,O75179,O95831,P04792,O60313,Q9UBX3,O43292,Q96N66,Q9Y263,Q96A33,O14936,P48449,P40855,Q8NHS3,Q99720,Q02750,Q15067,O43175,Q8TB36,P04080,Q3ZCQ8,Q15120 33 +Crumpled long bones 0.7523131672598008 1.9446516435053856 0.0518169192014177 1.0 0.3048810115415009 2 O75718 1 +Nonprogressive cerebellar ataxia 0.7512455516014228 1.9398966307825216 0.0523922536365148 1.0 0.3070801090096373 2 Q69YN2 1 +Ependymoma 0.7496218481958727 1.9264244522678955 0.0540513966546682 1.0 0.3128003549231505 3 O75874 1 +Genetic anticipation 0.7469750889679756 1.9208535705918783 0.0547501705538362 1.0 0.3146461439314743 2 P54886 1 +Hydrocele testis 0.7506212376933223 1.91983262831596 0.0548790440449371 1.0 0.3146461439314743 5 Q9NVI7,Q9UBX3 2 +Venous insufficiency 0.7505583224861212 1.9195483625071827 0.0549149718893102 1.0 0.3146461439314743 5 P21964 1 +Varicose veins 0.7505583224861212 1.9195483625071827 0.0549149718893102 1.0 0.3146461439314743 5 P21964 1 +Tall chin 0.746263345195727 1.9176761597923184 0.0551520864667993 1.0 0.3146461439314743 2 Q9UJX6 1 +Sacrococcygeal teratoma 0.746263345195727 1.9176761597923184 0.0551520864667993 1.0 0.3146461439314743 2 Q9UJX6 1 +Neoplasm of the middle ear 0.746263345195727 1.9176761597923184 0.0551520864667993 1.0 0.3146461439314743 2 Q9UJX6 1 +Bilateral camptodactyly 0.746263345195727 1.9176761597923184 0.0551520864667993 1.0 0.3146461439314743 2 Q9UJX6 1 +Short middle phalanx of finger 0.7469328251127533 1.914374271280821 0.0555723506022218 1.0 0.3159819788926514 3 Q03164 1 +Arm dystonia 0.747085569765673 1.9092327440613304 0.0562320740208506 1.0 0.3171939394392662 4 Q99720 1 +Respiratory arrest 0.7479359802996008 1.9003792618869475 0.0573833664059266 1.0 0.3191323416440079 7 P23786 1 +Contractures of the large joints 0.7423487544484131 1.900182273500397 0.0574092037251685 1.0 0.3191323416440079 2 Q9Y263 1 +Abnormal arm span 0.743165650162566 1.897468193841667 0.0577661727468654 1.0 0.3191323416440079 3 Q9UJX6 1 +Increased arm span 0.743165650162566 1.897468193841667 0.0577661727468654 1.0 0.3191323416440079 3 Q9UJX6 1 +Muscle weakness 0.3500009046101722 1.8973674982710265 0.0577794521370114 1.0 0.3191323416440079 247 P50402,P13073,Q70HW3,P12235,O43676,Q9NZJ7,O43819,P03886,P23786,Q96BR5,P36551,P01889,Q5JTZ9,Q92804,P22626,P00403,O15269,P61978,Q9Y4W6,P54886,Q969G3,O14979,O95831,P04792,Q9BPX6,O60313,P47985,Q06124,Q9HC21,Q9BUF5,P42858,O96000,Q9Y263,O14936,P51114,Q16637,P40855,Q99720,P51812,Q9Y6M9,P46976,Q9BQP7,Q15067,O43772,O75306,Q8TB36,P35637,Q13126,Q3ZCQ8,O75648,Q15120,Q96CU9,Q9BUK6,Q6DKK2 54 +Corneal neovascularization 0.7436770389309436 1.8884087751608816 0.0589710942025623 1.0 0.3244764855944007 5 P21964 1 +Central scotoma 0.7453980042268822 1.88476151717487 0.0594620427036483 1.0 0.3258381652758136 10 O75306,O00429,Q9H061,Q9Y287,Q8WWV3,P03886,Q8NHS3,O60313 8 +Rheumatoid factor positive 0.7407906754544594 1.8808390860845323 0.0599938114500198 1.0 0.3269553908164925 4 P15260 1 +Generalized edema 0.7398817964687601 1.876732972847454 0.0605547010686688 1.0 0.3281344152145046 4 O43175 1 +Ureteral duplication 0.7419918745520327 1.875748388694066 0.0606898380007105 1.0 0.3281344152145046 6 P23786 1 +Decreased number of large peripheral myelinated nerve fibers 0.7392749761212333 1.8739905798651817 0.0609317235091135 1.0 0.3281344152145046 4 O15269 1 +Hypokinesia 0.7430718619752787 1.8739435326327367 0.0609382084611804 1.0 0.3281344152145046 10 P42858,O95831 2 +Raynaud phenomenon 0.7418003597339013 1.8723082163153344 0.0611639747145675 1.0 0.3289570811915944 7 O75844 1 +Bilateral tonic clonic seizure with focal onset 0.7330960854092701 1.8587121925907408 0.0630679443048651 1.0 0.3348023851378414 2 Q9NZJ7 1 +Hyperesthesia 0.7330960854092701 1.8587121925907408 0.0630679443048651 1.0 0.3348023851378414 2 Q9NZJ7 1 +Abnormality of circulating enzyme level 0.4286187068856594 1.8576412381511211 0.0632199782685689 1.0 0.3351738356269434 82 Q9BQP7,P50402,P47985,P42166,O43772,Q08J23,Q5JRX3,O14979,O75648,Q15120,P23786,O95831,Q96BR5,Q9BUK6,P42167,Q9BPX6,P53985 17 +Slow decrease in visual acuity 0.7389505329154453 1.8571722578160137 0.0632866505698976 1.0 0.3351738356269434 8 O75306,O00429,P03886,Q969G3 4 +Diaphyseal thickening 0.7323843416370136 1.8555152137294917 0.0635226887372053 1.0 0.3359264314031148 2 P08236 1 +Generalized clonic seizure 0.7336182336182175 1.848391145424127 0.0645457787265377 1.0 0.3378229134866159 4 O14936,Q4G176,Q9NZJ7 3 +Retinal hemorrhage 0.7356425372192961 1.8467745186085336 0.0647798263922903 1.0 0.3378229134866159 6 Q9Y487 1 +Depression 0.3913735421694619 1.8457270811846 0.0649318429824878 1.0 0.3378229134866159 95 P12235,Q9NZJ7,Q08J23,P03886,P21964,O76024,P49589,P36551,P01889,Q5JTZ9,Q92804,P00403,Q9NXN4,P53992,Q9NZ01,P40818,Q96N66,P42858,Q9Y4P3,P51812,P35637,Q9BUK6,Q6DKK2 23 +Perisylvian polymicrogyria 0.7340836684761394 1.8448381825254068 0.0650610812797265 1.0 0.3378229134866159 5 Q9BVA1,Q15042,P42356 3 +Type 1 muscle fiber atrophy 0.735000214015425 1.8438389585574797 0.0652066131804463 1.0 0.3378229134866159 6 P50402 1 +Pleural effusion 0.7357030562639074 1.840604946853696 0.0656794722945581 1.0 0.3389544732318332 9 Q02750,Q9NZ08,P01889,Q06124 4 +Progressive leukoencephalopathy 0.7295807497775499 1.8362690251175664 0.0663178784761551 1.0 0.3415939180480355 3 Q5JTZ9 1 +Proximal upper limb amyotrophy 0.7330455056432578 1.8349005074777032 0.0665204324793506 1.0 0.3418558599594453 6 O14979,P50402 2 +Abnormality of the musculature of the upper arm 0.7330455056432578 1.8349005074777032 0.0665204324793506 1.0 0.3418558599594453 6 O14979,P50402 2 +Increased circulating igg level 0.7303297285445699 1.833480241362214 0.06673118429659 1.0 0.3421586434866115 4 P15260 1 +Furrowed tongue 0.7307720141717674 1.829755353207792 0.0672865296817293 1.0 0.3442229163173145 5 Q15042,P61978,P21912 3 +Abnormality of the alveolar ridges 0.7308931871817973 1.8250497583320164 0.0679935208925197 1.0 0.3462791071703334 6 Q15392 1 +Macrovesicular hepatic steatosis 0.7314986355914981 1.8250071631115867 0.0679999483963547 1.0 0.3462791071703334 7 O75648,P23786 2 +Heat intolerance 0.7283571124849921 1.8245258106609856 0.068072617917221 1.0 0.3462791071703334 4 P61978 1 +Goiter 0.7301833213043607 1.8217988532939828 0.0684855118225358 1.0 0.3466977811970956 6 P48735,P12235,O75874,P21912 4 +Broad palm 0.7300357519867295 1.8211229208687656 0.0685881738101668 1.0 0.3466977811970956 6 O95831 1 +Adrenal hyperplasia 0.7288379396322134 1.8209367771294145 0.0686164679005567 1.0 0.3466977811970956 5 P40818 1 +Abnormal corpus striatum morphology 0.7301430453182617 1.814957952468164 0.0695303714613024 1.0 0.3493571729945265 14 Q9BVA1,Q9Y3Z3,O43819,P42858,O95831,Q92947 6 +Hemoptysis 0.7256966464224532 1.8124370628585615 0.069918690422488 1.0 0.3505153144269862 4 Q9NZ08,P01889 2 +Abnormality of the tonsils 0.7275291966660278 1.8096353304675388 0.0703523572480033 1.0 0.3507500819875566 6 P21964,P53992 2 +Abnormal ldl cholesterol concentration 0.7281887393457687 1.8044677654094712 0.0711580080503149 1.0 0.3528225795947167 10 P50402,Q15800,Q8N511,P37268,Q9UJS0 5 +Abnormality of the musculature of the thigh 0.7264004829872426 1.8044584410691225 0.071159468571466 1.0 0.3528225795947167 6 O14979 1 +Abnormality of the thyroid gland 0.3866877527560235 1.8008323536279571 0.0717293077462704 1.0 0.3535257387806057 100 P12235,Q07021,P49327,P03886,P21964,O76024,P00403,P53992,P61978,Q969G3,Q13423,O60313,Q6PGP7,O75874,Q9Y3Z3,Q9Y4P3,Q9Y263,P42892,O95470,Q9Y285,Q9UJX6,P48735,Q96J02,Q9BUK6 24 +Abnormality of neuronal migration 0.374121054237632 1.800137549254685 0.0718389218435329 1.0 0.3535257387806057 129 Q08J23,O43924,Q7L7X3,P23786,Q86XL3,Q15392,Q9Y487,P61978,Q9NZ01,Q969G3,P07437,Q9BVA1,Q96N66,Q9HC21,Q9Y263,O14936,P40855,P51812,O43175,Q96PU5,P37268,Q9Y320 22 +Primary adrenal insufficiency 0.7271820878527036 1.7990675488124872 0.0720079961713198 1.0 0.3535257387806057 12 Q13423,P16435,Q969G3 3 +Cystic hygroma 0.7258467023172855 1.798967121382837 0.0720238817601592 1.0 0.3535257387806057 7 Q02750,Q06124,P61978,Q53EZ4,Q14739,Q99567 6 +Muscle abnormality related to mitochondrial dysfunction 0.7101254343654603 1.7979411862570012 0.0721863284470398 1.0 0.3535257387806057 28 P00403,Q9Y2R0,O43676,O75306,Q9UBX3,O96000,P03886,O75648,Q96CU9,Q9BUK6,O60313,Q9Y6M9 12 +Progressive hearing impairment 0.7266621451269623 1.7971424274847394 0.0723130116393391 1.0 0.3535257387806057 13 P03886,O76024,O60313,O60443 4 +Vitiligo 0.7241433936107837 1.794098852053175 0.0727973922566072 1.0 0.3535257387806057 6 P00403,P49327,P03886 3 +Hypoketotic hypoglycemia 0.7245080880252546 1.7927906704083825 0.0730064018482936 1.0 0.3535257387806057 7 O43772,P23786 2 +Neoplasm of the gallbladder 0.7188735070499368 1.7877808998372586 0.0738113635944421 1.0 0.3535257387806057 3 Q9NZJ7 1 +Vegetative state 0.7188735070499368 1.7877808998372586 0.0738113635944421 1.0 0.3535257387806057 3 Q9NZJ7 1 +Progressive peripheral neuropathy 0.7188735070499368 1.7877808998372586 0.0738113635944421 1.0 0.3535257387806057 3 Q9NZJ7 1 +Biliary tract neoplasm 0.7188735070499368 1.7877808998372586 0.0738113635944421 1.0 0.3535257387806057 3 Q9NZJ7 1 +Glucose intolerance 0.3868075509457374 1.7867878736818663 0.0739717800051602 1.0 0.3535257387806057 94 P12235,O43676,P50851,P18031,Q06136,Q9UKG1,P03886,O76024,P49589,P00403,Q5JRA6,O00429,P40818,O60313,Q9Y3Z3,Q9Y4P3,O96000,Q9Y6M9,O75844,P61457,O75306,Q13217,Q9Y6M1,Q96CU9,Q96J02,P31751,Q9Y375 27 +Abnormal cortical gyration 0.3788252602082866 1.784650717433338 0.0743179893832826 1.0 0.3535257387806057 115 P07437,Q9BVA1,Q9Y320,O43175,Q96N66,Q9HC21,Q08J23,Q9NZ01,Q969G3,O14936,Q7L7X3,Q9Y263,P23786,P40855,Q86XL3,P37268,Q15392,Q9Y487 18 +Joint hemorrhage 0.7163701067615746 1.7833250276447454 0.0745334096051002 1.0 0.3535257387806057 2 P38435 1 +Neoplasm of the adrenal cortex 0.7195284894757837 1.7783887849266875 0.0753400233549985 1.0 0.3535257387806057 5 P48735,O75874 2 +Connective tissue nevi 0.7135231316725992 1.770440336763278 0.0766538152027347 1.0 0.3568995300813279 2 Q9Y2U8 1 +Alkalosis 0.7175922598720743 1.7695187198104103 0.0768073496021539 1.0 0.357188850440916 5 P01889,Q9Y619 2 +Rhizomelia 0.7206517558012707 1.7691163579621303 0.0768744586038803 1.0 0.357188850440916 10 Q03164,O75718,Q15392,O00116 4 +Episodic vomiting 0.7194918759682432 1.767066833049987 0.0772170362614841 1.0 0.3580423687556677 8 P00403,P03886,Q9Y619,P61978 4 +Premature rupture of membranes 0.7167542232643963 1.7601160992142495 0.07838812364816 1.0 0.3603837388964796 6 Q9Y487 1 +Cytochrome c oxidase negative muscle fibers 0.7163825267383995 1.7584039473913111 0.0786788019671902 1.0 0.3603837388964796 6 O75648,Q9Y2R0 2 +Abnormal brainstem mri signal intensity 0.716981803239774 1.7581750732040315 0.0787177251527531 1.0 0.3603837388964796 17 O43676,P03886,O95831,Q96CU9,Q9Y6M9 5 +Focal cortical dysplasia 0.710676156583631 1.7575406041940491 0.0788257072056246 1.0 0.3603837388964796 2 P42345 1 +Hypoglycemic seizures 0.7162387673527814 1.7519314689940748 0.0797855926294706 1.0 0.3632052728751188 8 Q13423,P31751 2 +Abnormality of the proximal phalanx of the thumb 0.709252669039148 1.751085139817253 0.0799312455333653 1.0 0.3632052728751188 2 Q15233 1 +Chylothorax 0.7106851814816267 1.7505536974516005 0.0800228169436416 1.0 0.3632052728751188 3 Q06124 1 +Male infertility 0.712178300052603 1.744679617928544 0.0810406531221461 1.0 0.3671933254299995 5 Q06124,P51809 2 +Delayed menarche 0.7133754988144707 1.7445431505689155 0.0810644239633568 1.0 0.3671933254299995 6 Q9UJS0,Q06124,O75844 3 +Myositis 0.7137733254644428 1.73831889835614 0.0821546382068341 1.0 0.3690279749091213 9 Q9Y3Z3,P01889,P49327,Q9NZ08 4 +Neoplasm of the tongue 0.7117615071354575 1.7370965929602415 0.0823701226444588 1.0 0.3690279749091213 6 O43924,Q969G3 2 +Focal t2 hyperintense brainstem lesion 0.7132770744365728 1.7339661638446486 0.0829240869520693 1.0 0.3700053766597063 14 P03886,Q9Y6M9,O43676,Q96CU9 4 +Weakness of long finger extensor muscles 0.7049822064056921 1.7316965670132425 0.0833276022072262 1.0 0.3700053766597063 2 P31483 1 +Cystic liver disease 0.7091424886748053 1.730727692260246 0.0835003437243009 1.0 0.3700053766597063 5 Q7Z4L5,Q9UGP8 2 +Abnormality of the optic nerve 0.352669745667561 1.730318223359555 0.0835734354203641 1.0 0.3700053766597063 213 O43676,Q9NZJ7,O43819,O96028,P49327,P03886,P21964,O76024,P01889,P00403,P53992,P61978,Q9Y4W6,Q15042,Q9Y287,P31939,Q969G3,Q9P0J0,O95831,P38435,Q9NZ08,Q9BPX6,O60313,Q7LGA3,O43292,Q15813,Q7KZN9,P47985,Q9HC21,P42858,O96000,Q9Y263,O14936,P40855,Q8NHS3,P51812,Q9Y6M9,Q02750,Q15067,Q9NVI7,O75306,Q9H061,Q3ZCQ8,O75648,Q96PU5,Q96CU9,Q9BUK6,P37268 48 +Occipital meningocele 0.7085213378636003 1.72787094191406 0.0840113650258653 1.0 0.3704884757060423 5 P21964 1 +Cavernous hemangioma 0.7066533629388821 1.7255166323118172 0.0844344090242315 1.0 0.3715890740787663 4 Q02750,P21912 2 +Decreased pulmonary function 0.7060186394621522 1.7226079916961483 0.0849594388245229 1.0 0.3732087629455409 4 Q969G3 1 +Patchy changes of bone mineral density 0.705484330484306 1.720158940368197 0.0854035543117051 1.0 0.3744297852946059 4 Q13126,Q14739,Q15813 3 +Intestinal pseudo obstruction 0.7092503459484204 1.7193501262562838 0.0855506377434707 1.0 0.3745590926123369 8 P00403,P03886 2 +Myeloid leukemia 0.7032953805057781 1.716851125910639 0.0860063767737746 1.0 0.3745590926123369 3 Q06124 1 +Juvenile myelomonocytic leukemia 0.7032953805057781 1.716851125910639 0.0860063767737746 1.0 0.3745590926123369 3 Q06124 1 +Pectus excavatum of inferior sternum 0.7032953805057781 1.716851125910639 0.0860063767737746 1.0 0.3745590926123369 3 Q06124 1 +Abnormal cellular phenotype 0.3570537530625063 1.7150216913768002 0.0863412500697922 1.0 0.3756177741935844 158 O75880,P13073,P12235,Q70HW3,O43676,Q9NZJ7,P49327,P03886,P21964,P23786,P00403,P53992,Q9Y2R0,Q5JPH6,Q9Y4W6,Q969G3,Q9P0J0,Q9UBX3,Q6PGP7,Q7KZN9,P15260,O96000,Q9UJS0,P46976,Q9Y6M9,O75844,Q9BQP7,O43772,O75306,P35637,Q00325,P09601,Q3ZCQ8,O75648,Q96CU9,Q96J02 36 +Psychotic mentation 0.7058671351029073 1.7098608957967236 0.0872915990157277 1.0 0.3766958594940688 6 P03886,P40818 2 +Abnormal sternum morphology 0.3792743036736741 1.7058767421466765 0.0880310308860004 1.0 0.3785838322549654 100 Q03164,P50402,Q08J23,Q9Y619,Q9Y487,Q96AY3,P61978,O75718,Q7Z4L5,O95831,Q7LGA3,P07437,Q06124,Q9Y4P3,Q9Y263,Q96A33,P51812,P55795,Q02750,Q96J02,Q9BUK6 21 +Spastic ataxia 0.7037547760486957 1.7000851718520045 0.0891149060086839 1.0 0.3806224288025751 6 Q9H3L0,Q9Y4W6 2 +Mitochondrial myopathy 0.7016383280344839 1.698531607265734 0.0894074724054569 1.0 0.3806224288025751 21 P00403,P12235,O43676,O75306,O96000,P03886,Q53H12,Q96CU9,Q9BUK6,O60313,Q9Y6M9 11 +Redundant neck skin 0.7032921713442253 1.697943231695035 0.0895184767097247 1.0 0.3806224288025751 6 Q9Y487 1 +Abnormality of lipoprotein cholesterol concentration 0.7057468719640536 1.6970776449348164 0.0896819820209682 1.0 0.3806536215418816 12 P50402,Q15800,Q8N511,P37268,Q9UJS0 5 +Abnormality of the female genitalia 0.3718161933284736 1.6970102137376608 0.08969472954903 1.0 0.3806536215418816 116 Q08J23,O96028,P49327,P21964,Q9Y619,Q5JTZ9,Q15392,P53992,Q15042,Q16740,Q9BW83,P40818,Q06124,O75874,Q9Y4P3,P40855,P51812,O75844,P51809,O43175,P48735,P31751,P16435 23 +Synostosis involving digits 0.6967971530249197 1.6944436805466938 0.0901810051468001 1.0 0.3819979231171657 2 Q15233 1 +Porokeratosis 0.69679715302491 1.6944436805466516 0.0901810051468081 1.0 0.3819979231171657 2 P14324 1 +Tetany 0.7000952190145946 1.6890495155369547 0.0912099413379734 1.0 0.3852701083507463 5 P21964,P53992 2 +Phenotypic variability 0.3791831427107257 1.6880649785419564 0.0913987562830229 1.0 0.3857061746887495 90 Q70HW3,P50995,Q9NZJ7,P03886,P36551,P00403,Q9Y4W6,O00429,Q969G3,O14979,O60313,P00374,Q9BVA1,Q92733,Q9Y3Z3,Q9BUF5,Q9Y263,P21912,Q8TD16,P46976,Q14671,O95470,Q9H061,Q15058,O95140,Q53H12,Q6P4A7,Q9Y375 28 +Cardiovascular calcification 0.7029260013600673 1.687386533392475 0.0915290515558444 1.0 0.3858947009936304 9 O75844 1 +Decreased plasma carnitine 0.7009562033384316 1.676225682077486 0.0936939955278162 1.0 0.3925524381941605 10 O43772,O75648,P23786 3 +Hypothermia 0.7004715127047059 1.675832078857862 0.0937710887679434 1.0 0.3925524381941605 9 O43772,P03886 2 +Clonic seizure 0.6970362349070285 1.6749248159029655 0.0939489839591889 1.0 0.3925524381941605 5 O14936,Q4G176,Q9NZJ7 3 +Vocal cord paresis 0.6951525781045129 1.672702731068909 0.0943858313406016 1.0 0.3925524381941605 4 Q8TB36,O95140 2 +Diastasis recti 0.6918149466192172 1.6717104885423577 0.0945814248957501 1.0 0.3925524381941605 2 P42345 1 +Peripheral neuropathy 0.3540801641796103 1.6711150324578097 0.0946989587021727 1.0 0.3925524381941605 149 P12235,Q9NZJ7,O43819,P48643,P03886,O76024,Q96BR5,P36551,Q15041,P01889,P22626,Q92947,P00403,O15269,Q9Y2R0,Q9Y4W6,Q15042,P54886,Q9P0J0,O95831,P04792,Q9BPX6,O60313,Q15813,Q7KZN9,Q9Y3Z3,Q9HC21,Q9Y6X9,Q15067,Q9NVI7,O75306,O95470,Q8TB36,Q13217,Q15120,Q96CU9 36 +Abnormality of the achilles tendon 0.6997639602333754 1.6684555621705637 0.0952253263646076 1.0 0.3933827185383013 12 P50402,Q8N2K0,Q08J23,Q15041,Q8TD16,O60313 6 +Fatty replacement of skeletal muscle 0.6955028112371626 1.6678381887430018 0.0953478526704501 1.0 0.3935281794741013 5 P51114 1 +Episodic hypertension 0.6900355871886132 1.6635811647647012 0.0961961585028661 1.0 0.3943390026977832 2 P21912 1 +Decreased calvarial ossification 0.6927767669098763 1.6617637373458265 0.0965601557571607 1.0 0.3943390026977832 4 O75844 1 +Achilles tendon contracture 0.6975614408214112 1.660143057914813 0.0968856765982262 1.0 0.3943390026977832 10 P50402,Q8N2K0,Q08J23,Q9Y3E5,Q8TD16,O60313 6 +Dystrophic toenail 0.6936389325877702 1.6531612235897784 0.0982980558746429 1.0 0.3985768740425163 6 O75844 1 +Small earlobe 0.6935947929061392 1.6529560862106534 0.0983398011837759 1.0 0.3985768740425163 6 P21964 1 +Elevated gamma glutamyltransferase level 0.6888678733063108 1.6507731592145731 0.0987849027695126 1.0 0.3996620796967627 3 Q9UJS0 1 +Distal sensory impairment of all modalities 0.6912004212146584 1.6479334132760666 0.0993663358955712 1.0 0.4012939748040676 5 O15269 1 +Ptosis 0.3509701581443665 1.6473492944198584 0.0994862711606208 1.0 0.4014186429014485 193 Q03164,P50402,P12235,O43676,Q9NZJ7,Q08J23,O43819,O96028,P03886,P21964,O76024,Q86XL3,P01889,P53992,Q5JPH6,P61978,Q9Y4W6,Q15042,Q969G3,Q9BPX6,O60313,Q7LGA3,Q7KZN9,Q06124,Q9Y3Z3,Q9BUF5,P42858,O96000,Q96A33,P40855,Q9Y6M9,Q9BQP7,Q02750,O75306,O95470,P35637,O75648,Q96CU9,Q96J02 39 +Gait disturbance 0.3219699000540781 1.6467905125199511 0.0996011121272082 1.0 0.401522551303513 275 Q03164,P50402,P12235,Q9NZJ7,O43819,O43924,O15118,P48643,P49327,P03886,P49589,Q96BR5,Q9Y619,Q15041,P01889,P22626,Q96AY3,P00403,O15269,Q9NXN4,P61978,Q9Y4W6,Q969G3,O95831,P40818,Q9NZ08,P04792,Q9BPX6,O60313,Q7LGA3,O43292,Q9BVA1,Q96N66,Q9Y3Z3,Q9HC21,P42858,Q9Y4P3,O14936,Q99720,P51812,P46976,O75844,P55795,Q9H3L0,O14949,Q15067,Q9NVI7,Q13217,Q8TB36,P35637,Q5JRX3,O75648,Q15120,Q96CU9,Q9BUK6 55 +Steroid resistant nephrotic syndrome 0.6905939511479634 1.645125085440874 0.0999440184094937 1.0 0.4024276780367471 5 Q8N1F7,Q12769,Q9BW27 3 +Aplasia hypoplasia involving the femoral head and neck 0.6938976161868792 1.6448331904622775 0.1000042155316522 1.0 0.4024276780367471 9 O95831,P15260 2 +Hemorrhage of the eye 0.6929343135745224 1.6381894979414535 0.1013821697223438 1.0 0.4061934669841008 10 Q9Y487 1 +Multiple enchondromatosis 0.6900525037577966 1.636482677551695 0.1017386081875013 1.0 0.4064243542032349 6 P48735,Q06124 2 +Abnormal peripheral nervous system morphology 0.3566524443682339 1.6362744164510423 0.1017821679506165 1.0 0.4064243542032349 140 P12235,Q9NZJ7,O43819,P48643,P03886,O76024,Q96BR5,Q9Y619,P22626,Q92947,P00403,O15269,Q9Y4W6,Q969G3,O95831,P04792,Q9BPX6,O60313,Q9HC21,Q9BUF5,Q16637,P40855,Q99720,P51812,Q9BQP7,Q15067,Q9NVI7,Q8TB36,P35637,Q15120,Q6DKK2 31 +Weakness due to upper motor neuron dysfunction 0.3662653647454651 1.6361462377405864 0.1018089851110388 1.0 0.4064243542032349 120 Q9NZJ7,P48643,P49327,P03886,Q9Y619,Q15041,P01889,P00403,Q5JPH6,Q9Y4W6,P54886,Q969G3,Q9P0J0,O95831,P40818,Q13423,Q9NZ08,O60313,Q9UBX3,Q7KZN9,Q9BVA1,Q9Y3Z3,O75306,P35637,Q96CU9,Q6DKK2 26 +Abnormal circulating lipid concentration 0.5237222668614878 1.6282165753700908 0.1034789713622419 1.0 0.4094642001138054 66 O75880,P50402,Q9NZJ7,Q8N511,P23786,Q15392,P42858,Q9Y4P3,P40855,Q9UJS0,O75844,Q9NVI7,O43772,Q9Y285,O95470,Q15800,O75648,P37268,P31751 19 +Abnormality of skeletal muscle fiber size 0.6890409464850814 1.6205870671383502 0.1051062277103975 1.0 0.4113680528447862 17 Q9BPX6,O95831,Q9BUK6 3 +Abnormal brain lactate level by mrs 0.6882432658498149 1.618110784727382 0.1056387247172034 1.0 0.4113680528447862 9 P00403,O75306,O00429,O43819,P03886 5 +Increased ldl cholesterol concentration 0.6868719730692183 1.6177804413420964 0.1057099229021854 1.0 0.4113680528447862 7 P50402,Q8N511 2 +Abnormality of muscle size 0.350494022513896 1.6172301932870454 0.1058286011614342 1.0 0.4113680528447862 171 P50402,P12235,O43819,P48643,P49589,Q96BR5,P22626,Q92804,Q9Y487,O15269,P61978,Q9Y4W6,Q9BW83,O14979,O95831,P40818,P04792,O60313,Q7LGA3,Q9BVA1,Q9HC21,Q9Y4P3,Q96A33,Q16637,P55263,Q99720,P51812,P46976,Q9BQP7,Q9NVI7,O43175,Q8TB36,P35637,Q13126,O75648,Q15120,Q9BUK6,Q6DKK2,Q6P4A7 39 +Polyneuropathy 0.6879865613800491 1.61536633416017 0.1062313862975536 1.0 0.4113680528447862 17 Q9NZJ7,Q9HC21,Q15120,P03886,O95831,O60313 6 +Abnormal left ventricular outflow tract morphology 0.6821908743441495 1.6129075546058522 0.1067645936640495 1.0 0.4113680528447862 4 O43684,Q06124 2 +Subvalvular aortic stenosis 0.6821908743441495 1.6129075546058522 0.1067645936640495 1.0 0.4113680528447862 4 O43684,Q06124 2 +Abnormality of macular pigmentation 0.6818985602323105 1.611555849640333 0.1070586246777236 1.0 0.4113680528447862 4 Q8NHS3 1 +Symptomatic seizures 0.6865072942960608 1.6098958143640418 0.1074206029212971 1.0 0.4113680528447862 9 Q13423,P31751,P53985 3 +Upper limb spasticity 0.6833422161608278 1.60521925663859 0.1084455610754884 1.0 0.412943182721197 6 Q99720 1 +Abnormality of circulating glucocorticoid level 0.686054340227484 1.603769126015275 0.108764952343507 1.0 0.4135799598394112 11 Q13423,P16435 2 +Hyperlipoproteinemia 0.6819576395829324 1.5912722119017566 0.1115483276935838 1.0 0.4219809499872913 8 P50402,Q8N511 2 +Turricephaly 0.6818035273618006 1.5905454342272043 0.111711912877628 1.0 0.4219809499872913 8 P21964,P53992 2 +Abnormality of body mass index 0.6757069425563782 1.5901911984878927 0.111791713841763 1.0 0.4219809499872913 3 P42858 1 +Abnormality of the nasal tip 0.3711647214765091 1.58842688870033 0.112189841245885 1.0 0.4231293845148149 89 Q03164,P53992,P61978,O43924,Q969G3,Q96A33,O14936,P21964,P23786,O95831,Q9Y487,P51812,P16435,O43292,O75844 15 +Bile duct proliferation 0.6748608173096561 1.5862868817595384 0.112674246737312 1.0 0.4239308006592909 3 Q9NSD9 1 +Abnormal sputum 0.6771912223950177 1.5829079501936734 0.1134424464289542 1.0 0.4239308006592909 5 Q9NZ08,P01889 2 +Lactose intolerance 0.673440156931817 1.5797289687244482 0.1141689485306229 1.0 0.4240538606236794 3 Q14566 1 +Abnormality of the basal ganglia 0.47807223461745 1.5766149068088269 0.1148841606379176 1.0 0.4247661337405791 72 P00403,Q7KZN9,Q9BVA1,Q96N66,Q9Y3Z3,O43819,Q08J23,P42858,Q9NZ01,P03886,P23786,O95831,Q96CU9,Q9BPX6,O60313,Q92947 16 +Decreased activity of mitochondrial complex i 0.6701057127291075 1.5763862849202892 0.1149368072076075 1.0 0.4247661337405791 27 Q70HW3,Q5JPH6,O43676,O96000,P03886,O75648,Q96CU9,Q9UBX3,Q9Y6M9 9 +Myopathy 0.4110999165577121 1.57543078786356 0.1151570425096624 1.0 0.4250719005659693 81 P50402,P12235,O43676,P03886,O76024,P23786,P00403,O14979,P42167,P40818,O60313,P42166,Q9Y4P3,P51114,P46976,Q9BQP7,O75306,Q00325,Q13126,O75648,Q9BUK6 21 +Abnormal middle phalanx morphology of the hand 0.6764636513634097 1.5730965598588014 0.1156964613951061 1.0 0.4267135446053546 6 Q03164,Q15233 2 +Abnormal brainstem morphology 0.4634306122464158 1.5710008633787549 0.1161824482454225 1.0 0.4267598160082473 74 P07437,Q9BVA1,O43676,O75306,Q13217,O43819,Q969G3,O96000,O14936,P03886,O95831,Q96CU9,O60313,Q9Y6M9 14 +Autoamputation 0.6749497808963482 1.5660169168124445 0.1173446568332201 1.0 0.4295884528359609 6 O15269 1 +Ventricular preexcitation 0.6734857326208323 1.565656289423062 0.1174291044805644 1.0 0.4295884528359609 5 P00403,P03886 2 +Bruxism 0.674590835567183 1.5643377881778513 0.1177382622838578 1.0 0.4300213517936364 6 P42858 1 +Enlarged ovaries 0.6712224077585455 1.5620954566099658 0.1182655030613921 1.0 0.4315398466234845 4 P16435,P21912 2 +Abnormal erythrocyte sedimentation rate 0.6731870733404395 1.557769179220729 0.1192879746208626 1.0 0.4339232458565196 6 P15260 1 +Abnormal circulating non proteinogenic amino acid concentration 0.6722296355243285 1.5532873463902896 0.1203545018864153 1.0 0.4364669438010081 6 P03886,Q9Y619 2 +Abnormal mitochondria in muscle tissue 0.6754618512644014 1.553203105189903 0.1203746197347799 1.0 0.4364669438010081 17 P00403,O43676,O75306,O96000,P03886,Q96CU9,Q9Y6M9 7 +Thoracic kyphoscoliosis 0.671931260417322 1.5518903511007849 0.120688462039199 1.0 0.437253133770635 6 O75844 1 +Cervical spinal canal stenosis 0.6654804270462649 1.5508701189029384 0.1209328125995412 1.0 0.437786495089263 2 Q9NSE4 1 +Mental deterioration 0.36808332802046 1.5495647156585235 0.1212460273309445 1.0 0.4385680940453991 90 Q03164,Q9NZJ7,O43819,O15118,Q9BQE5,P03886,P21964,O76024,P22626,Q5JTZ9,Q92947,Q9Y487,P00403,Q9NXN4,Q9Y287,O60313,P42858,Q8NHS3,O75306,O95470,P04080,P35637 22 +Exercise induced muscle cramps 0.6679504039736919 1.539846818783438 0.1235976965266947 1.0 0.4452876244970528 5 P23786 1 +Tetraplegia 0.6721245643817999 1.536938238552102 0.1243084344017757 1.0 0.446776805302076 11 O95831 1 +Absent nipple 0.6619217081850517 1.5344584820931686 0.1249168997111507 1.0 0.4486059497993278 2 Q6NUK1 1 +Coxa vara 0.6705394148009892 1.531433254514349 0.1256623505922576 1.0 0.4498492566475814 10 Q96AY3,O95831,Q96HY6,Q9Y487 4 +Unexplained fevers 0.6662155856099536 1.5251042039982308 0.1272331088187082 1.0 0.4530003648884254 6 Q9Y3Z3 1 +Abnormality of amino acid metabolism 0.6614453542185836 1.524239280403855 0.1274489489284156 1.0 0.4530003648884254 3 P18074,Q92889 2 +Flat nasal alae 0.6614453542185836 1.524239280403855 0.1274489489284156 1.0 0.4530003648884254 3 P18074,Q92889 2 +Atrophy degeneration involving the spinal cord 0.6655390966928924 1.5219307549953591 0.1280264320430446 1.0 0.4530003648884254 6 P48643,Q13217,P54886 3 +Enchondroma 0.6683605602801219 1.5210049316365957 0.1282585997428125 1.0 0.4530003648884254 10 Q9Y3Z3,Q06124,P48735 3 +Broad phalanx of the toes 0.6622722772884029 1.5204990458672336 0.1283855983662416 1.0 0.4530003648884254 4 O14936 1 +Proximal amyotrophy 0.66860734600905 1.5184062443977588 0.1289120184746837 1.0 0.4530003648884254 12 Q9BQP7,Q16637,P35637,O14979 4 +Head titubation 0.6646667503676515 1.517837569965701 0.1290553513460701 1.0 0.4530003648884254 6 Q99720 1 +Branchial cyst 0.6572953736654892 1.5130965131180247 0.1302551452067173 1.0 0.4553983392351804 2 Q9UHX1 1 +Spondyloepiphyseal dysplasia 0.6572953736654814 1.5130965131179896 0.1302551452067262 1.0 0.4553983392351804 2 Q9NSE4 1 +Poikiloderma 0.661916636978976 1.511662569335346 0.1306197254365546 1.0 0.456005501582147 5 Q92889,P18074,Q9H1A4,O75431 4 +Skin plaque 0.6615598657929909 1.5099944567722283 0.1310448386264622 1.0 0.4571355167875117 5 Q06136 1 +Schizophrenia 0.6658862052066197 1.5073643781981567 0.1317172842315555 1.0 0.4580584021098736 18 P16615,P53992,Q9NZJ7,Q9BQE5,P21964,Q9BUK6 6 +Prolonged partial thromboplastin time 0.6608478802992468 1.5066649868202415 0.1318965505554947 1.0 0.4580584021098736 5 O60762,Q7Z2Z2,P38435,P49257 4 +Abnormal thyroid hormone level 0.6540925266904001 1.4982902457460778 0.1340578572479647 1.0 0.4640543491678778 2 O14654 1 +Optic neuropathy 0.6641543618466313 1.4968603152190134 0.1344296081576885 1.0 0.4649840705807385 17 P03886,Q9Y6M9,O43676,Q96CU9 4 +Abnormal lower limb bone morphology 0.3430311639146101 1.4958406432083382 0.1346951872296358 1.0 0.4655454055551906 150 Q03164,Q9NZJ7,Q08J23,O43924,P21964,Q9Y619,Q15392,Q9Y487,Q96AY3,P53992,O75718,Q7Z4L5,O95831,Q96HY6,Q7LGA3,Q13555,P15260,P42858,Q96A33,O14936,P51812,O75844,O00116,O43175,O75648,Q32P28,P16435 27 +Hypogonadism 0.3797530830838607 1.49331249933218 0.1353554052265975 1.0 0.467110881589797 84 Q9BQP7,P00403,P51809,Q06124,O43175,Q9BT22,O95470,Q16740,Q969G3,Q9BW83,Q9Y4P3,P03886,O76024,P48449,O60313,O75844 16 +Platybasia 0.6565379017576689 1.4864954967847406 0.1371481071095868 1.0 0.471852304383899 5 P21964 1 +Disproportionate short limb short stature 0.6595072954800814 1.4725953908829317 0.1408601683713497 1.0 0.4816819262895851 16 Q03164,O00116,O75718,Q32P28,Q15392,Q7LGA3 6 +Vascular skin abnormality 0.3608334510034619 1.4718589022111068 0.1410589836494571 1.0 0.4819960874208516 102 P51648,P53992,Q06124,Q9Y3Z3,Q06136,Q08J23,Q13126,P03886,P21964,Q99829,P40818,Q9Y487,P01889,O75844 14 +Dyschromatopsia 0.6536578153099931 1.4660926773458165 0.1426230403780546 1.0 0.4828598563033517 6 O60313,Q9H061,Q9Y6X9,Q9Y4W6 4 +Posterior pharyngeal cleft 0.6469750889679757 1.4653392983704854 0.1428283697504642 1.0 0.4828598563033517 2 P29372 1 +Airway obstruction 0.6577924402812099 1.4646300672449992 0.14302187411585 1.0 0.4828598563033517 13 P53992,P09601,P21964,Q96HY6,O75844 5 +Lower limb pain 0.6500871930590912 1.4636896013071985 0.1432787780223536 1.0 0.4831778054378058 4 O95140,P54886 2 +Increased circulating igm level 0.6539584647323798 1.462816057507302 0.1435177180364903 1.0 0.4831778054378058 7 P49327,P15260 2 +Vaginal neoplasm 0.64973895237717 1.4620632045242432 0.1437238906616693 1.0 0.4834056531433908 4 O43684,O60566 2 +Nasogastric tube feeding in infancy 0.6550988402715314 1.4604606976741228 0.1441635015484408 1.0 0.484161625543087 9 O75648,Q9NZJ7 2 +Feeding difficulties in infancy 0.3418220902890662 1.4579996516192395 0.1448406390423193 1.0 0.4860735369796972 145 O75880,Q9NZJ7,Q01105,O43819,O43924,Q7L7X3,O76024,P21964,P23786,Q9Y619,Q9Y487,P53992,P61978,Q7Z4L5,O95831,O60313,P47985,Q06124,Q9Y3Z3,Q9BUF5,Q9Y263,Q9UGP8,O14936,P40855,Q99720,P51812,Q02750,Q9NVI7,O75306,Q9Y285,P35637,O75648,Q96J02,P37268 34 +Abnormal circulating fatty acid anion concentration 0.655571722582602 1.457145567806068 0.1450762021983793 1.0 0.4861508795653574 11 O43772,O75648,P23786 3 +Chronic fatigue 0.652529384735022 1.4560533301046092 0.1453778775769059 1.0 0.4864276868887267 7 Q13423 1 +Alopecia totalis 0.6513357642925951 1.4551582677759327 0.1456254511791432 1.0 0.4867365131241791 6 O75844 1 +Acantholysis 0.646211148363919 1.445578865365545 0.1482953580409312 1.0 0.4914464549194683 4 P01889 1 +Generalized hyperkeratosis 0.646839306521592 1.4410211592643265 0.1495787051206241 1.0 0.49460838149571 5 O75844,P21912 2 +Functional abnormality of the inner ear 0.334815207913571 1.436788626034042 0.150778063209265 1.0 0.4978437588894926 217 P12235,O43676,Q9NZJ7,O96028,P03886,O76024,P01889,Q92947,P00403,O15269,P61978,Q16740,O95831,P42167,Q9NZ08,O60313,O60443,Q7LGA3,Q9NR28,Q06124,P42166,Q9Y4P3,O96000,Q9Y263,O14936,P40855,P55263,P51812,Q9Y6M9,O75844,P46976,Q02750,Q15067,O75306,O95470,Q13217,Q9H061,P35637,P38159,Q15120,Q96CU9 41 +Short ribs 0.6491925556092052 1.43596642554058 0.1510118951729868 1.0 0.4978863288549024 8 Q7Z4L5,Q9Y619 2 +Chronic pulmonary obstruction 0.6462659049858478 1.4312617783355874 0.1523552038212434 1.0 0.4990049154100585 6 P21964,P09601 2 +Puberty and gonadal disorders 0.3389282652924062 1.4304094311955935 0.1525995429910518 1.0 0.4990049154100585 150 P03886,O76024,P00403,Q16740,Q969G3,Q9BW83,Q13423,O60313,Q7LGA3,Q06124,O75874,P42858,Q9Y4P3,O14936,P48449,Q9UJS0,O75844,P51809,Q9BQP7,Q02750,O43175,Q9BT22,O95470,Q15800,P48735,O75648,P16435 27 +Thick hair 0.6456953133913369 1.4236786665616572 0.1545395119996881 1.0 0.5021698490141274 7 Q9Y487 1 +Distal peripheral sensory neuropathy 0.6427210172952501 1.421677214444891 0.1551199777572405 1.0 0.5026355855972628 5 P03886 1 +Toe walking 0.6470689656483406 1.417071914076823 0.1564619030403566 1.0 0.5033360435423894 20 P50402,Q9NZJ7,P54886,P35637,Q9Y6X9,O95831,Q99720 7 +Hypoventilation 0.6466538964953363 1.4140074392195086 0.1573597182349229 1.0 0.505863231158914 11 O43819,P61978 2 +Underdeveloped supraorbital ridges 0.6457127541346162 1.4122258076603178 0.1578834838648997 1.0 0.5071852186593748 10 Q02750,Q08J23,P40855,P16435 4 +Brittle hair 0.6456596763332755 1.4041717683996104 0.1602677064905102 1.0 0.5119337195500598 14 Q02750,Q9NVI7,P49589,Q9Y487,O75844 5 +Abnormal activity of mitochondrial respiratory chain 0.5973825355933563 1.400809367687681 0.1612710866128714 1.0 0.5119337195500598 44 Q7KZN9,Q70HW3,Q5JPH6,Q9Y2R0,O43676,O75306,O96000,Q3ZCQ8,P03886,O75648,Q96CU9,Q9UBX3,Q9Y6M9 13 +Biliary atresia 0.6348270948991116 1.400411904575506 0.1613900071728387 1.0 0.5119337195500598 3 Q92889 1 +Abnormal circulating serine concentration 0.6344458126344436 1.3986322080594291 0.161923302797327 1.0 0.5119337195500598 3 O43175 1 +Optic disc pallor 0.6117346631302086 1.3956444495158726 0.1628215901247376 1.0 0.5120983298619627 39 Q9Y375,O43676,P04439,Q9Y4W6,O75306,Q9H061,Q9Y287,Q8WWV3,O96000,O14936,P03886,O95831,Q9BUK6,Q6P4Q7,Q96CU9,Q8NHS3,O60313,Q9Y6M9 18 +Breech presentation 0.6405471824295205 1.3947551296674914 0.1630896939752526 1.0 0.5125838568664322 8 O60313,Q9Y619 2 +Decreased absent ankle reflexes 0.6424597302510989 1.3936868639588995 0.1634121847007423 1.0 0.5131184479810998 11 P12235,Q15120,O60313,Q15041 4 +Scotoma 0.6432114300328914 1.393288300473248 0.163532627100674 1.0 0.5131184479810998 13 P04439,O75306,Q9H061,Q9Y287,Q8WWV3,P03886,Q8NHS3,O60313 8 +Abnormal circulating metabolite concentration 0.3166535472571139 1.3900528290417085 0.1645128357929601 1.0 0.5142436168003256 301 O75880,P50402,P12235,Q70HW3,O43676,Q9NZJ7,Q14C86,Q08J23,O43819,Q8N511,P48643,P03886,P21964,P23786,Q96BR5,Q9Y619,P36551,Q9BWD1,Q15392,Q92947,Q9Y487,P53992,O14979,O95831,Q8NFH4,P40818,P42167,Q13423,Q9BPX6,P53985,P47985,P42166,P15260,P42858,Q9Y4P3,O96000,Q9UGP8,O14936,P40855,P55263,Q8N1F7,Q9UJS0,Q9Y6M9,O75844,Q9BQP7,Q9H3L0,Q9NVI7,O43175,O43772,O95470,Q9BT22,Q9Y285,O75306,Q15800,Q5JRX3,P48735,O75648,Q15120,Q96CU9,Q9BUK6,P37268,P31751 62 +Atrial flutter 0.6306049822064022 1.3893236870391834 0.1647343441780266 1.0 0.5142436168003256 2 O75694 1 +Abnormality of acid base homeostasis 0.3367693758085784 1.3887251199019166 0.1649163525997301 1.0 0.5142436168003256 146 O75880,P13073,Q70HW3,O43676,O43819,P03886,P23786,Q9Y619,Q9BWD1,P01889,Q5JTZ9,Q92947,P00403,Q5JPH6,O95831,P40818,Q9UBX3,P53985,Q7KZN9,P47985,Q9HC21,O96000,Q9UJS0,Q9Y6M9,Q9H3L0,O14949,Q9NVI7,O75306,Q00325,Q5JRX3,Q3ZCQ8,P48735,O75648,Q96CU9,Q6P4A7 35 +Fragile nails 0.6400967629453985 1.3886163032868135 0.1649494571091814 1.0 0.5142436168003256 9 Q9Y487 1 +Joint hypermobility 0.3787380271421839 1.3884930187543127 0.1649869691354051 1.0 0.5142436168003256 83 Q03164,P53992,Q06124,Q9Y285,Q01105,Q08J23,P42858,Q9Y4P3,Q9Y263,Q15042,O75648,P21964,O75179,Q96PU5,Q9Y619,P51812,Q7LGA3,Q9Y487 18 +Skeletal muscle atrophy 0.338625995348223 1.3874704909126077 0.1652983432495003 1.0 0.5147830657978075 143 P50402,P12235,P50995,O43819,P48643,P49589,Q96BR5,P22626,Q92804,O15269,Q8N2K0,Q9Y4W6,P31483,P54886,Q9BW83,O14979,O95831,P40818,P04792,O60313,Q15813,Q9BVA1,Q9HC21,Q16637,Q9Y6X9,P55263,Q99720,P51812,Q8TD16,P46976,Q9BQP7,Q9NVI7,O43175,Q8TB36,P35637,Q13126,Q96B26,Q15120,Q15165,Q9BUK6,Q6DKK2,Q6P4A7 42 +Choanal stenosis 0.6337364866721347 1.387174759651273 0.1653884799811904 1.0 0.5147830657978075 4 P16435 1 +Sparse lateral eyebrow 0.6340158286453302 1.380727296202476 0.167362825180269 1.0 0.5186643110678216 5 Q08J23 1 +Intellectual disability mild 0.3516963918855891 1.380687467252144 0.1673750764092088 1.0 0.5186643110678216 110 Q01105,Q15233,Q08J23,Q8WWV3,Q7L7X3,P49589,P21964,Q9UBB6,P53992,Q9Y4W6,Q9NZ01,Q7LGA3,O43292,Q6PGP7,P16615,Q06124,Q96N66,P42858,P51812,Q9BT22,Q13217,P04080,Q15800,Q5JRX3,Q9UJX6,Q92889,O75648,Q9BUK6,Q6P4A7 29 +Axonal degeneration 0.6353073870674564 1.3743684531969915 0.1693273247275384 1.0 0.5211427452383756 7 Q6DKK2 1 +Slender long bone 0.6376456561081532 1.3659919522289763 0.1719414893755777 1.0 0.5232547553110931 13 Q32P28,Q9Y619,Q96J02,P37268,Q9Y487 5 +Multifocal cerebral white matter abnormalities 0.6320045817872106 1.363889390739045 0.1726023803761904 1.0 0.5248869898555287 6 Q9Y619 1 +Hyperpigmentation of the skin 0.3992745904567501 1.363545158816463 0.1727107623598289 1.0 0.5248869898555287 80 P07437,P16615,P51648,Q06124,Q06136,O75648,P40818,Q13423,O75844 9 +Abnormal b cell morphology 0.632371786885524 1.36041380634953 0.1736990118926531 1.0 0.5252600659677888 7 Q13432,P49327 2 +Advanced ossification of carpal bones 0.6241992882562419 1.3595027878288686 0.1739873196809707 1.0 0.5252600659677888 2 Q9BYW2 1 +Abnormal circulating follicle stimulating hormone concentration 0.6320634030466747 1.3589474108127964 0.1741632537671056 1.0 0.5254041397110744 7 P16435,Q969G3 2 +Abnormal waist to hip ratio 0.6305212775297345 1.356870480579819 0.1748223678796445 1.0 0.5270397404906743 6 P18031,P31751,O76024,Q9Y6M1 4 +Acne 0.6353661374293782 1.3548034026533746 0.1754802022281953 1.0 0.5277365032756979 13 P53992,P21964,P40818,Q9NZ08,P01889 5 +Urticaria 0.63370488133031 1.3543054390755993 0.1756389516116145 1.0 0.5277365032756979 10 P49327,P51648,Q92889 3 +Bradycardia 0.6325964926282364 1.352607007320181 0.1761812126362354 1.0 0.5286524419290498 9 O43772,P47985 2 +Autoamputation of digits 0.6215614603175503 1.338410941852243 0.1807625139997493 1.0 0.5381087520454888 3 P48643 1 +Acral ulceration 0.6215614603175503 1.338410941852243 0.1807625139997493 1.0 0.5381087520454888 3 P48643 1 +Abnormality of thyroid physiology 0.424885074629967 1.333215821204867 0.1824609888175103 1.0 0.5411085149578136 76 P00403,P53992,P61978,Q9Y3Z3,Q9Y285,O95470,Q9Y4P3,Q969G3,O76024,P03886,P21964,Q96J02,Q9BUK6,Q13423,O60313 15 +Decreased circulating iga level 0.6262691604844409 1.3313797846990445 0.1830640776435037 1.0 0.5411085149578136 7 P13051,P50851,Q96J02 3 +Punctate cataract 0.6196051283741326 1.3292545402774845 0.1837640067212924 1.0 0.5425507568885612 3 P08670 1 +Spondyloepimetaphyseal dysplasia 0.6257872998004831 1.3290859495486065 0.1838196152138524 1.0 0.5425507568885612 7 O95831 1 +Abnormal placenta morphology 0.6270006608160266 1.3257076912045496 0.184936538840589 1.0 0.5438709575210223 9 O75844,Q6PGP7,O43175 3 +Generalized limb muscle atrophy 0.6223182432097739 1.3180204539285214 0.1874968009284841 1.0 0.5450253691194424 6 P49589,O43819 2 +Antineutrophil antibody positivity 0.6167800689759456 1.3160270615612153 0.1881649599178727 1.0 0.5450253691194424 3 Q96J02 1 +Aplasia hypoplasia of the phalanges of the toes 0.6165895336418632 1.3151347307320955 0.1884646260832352 1.0 0.5451925993306426 3 Q9ULC3,P02545 2 +Thin ribs 0.626509774599409 1.3112891541320488 0.189760091264056 1.0 0.5465661924976675 13 Q32P28,O95831,O75844 3 +Polymicrogyria 0.46156607090941 1.310689621939808 0.1899626463222399 1.0 0.5467188039427429 70 P07437,Q9BVA1,O43175,Q96N66,Q01105,Q08J23,Q9NZ01,Q7L7X3,P23786,P40855,Q9Y487,P37268,Q15392,Q9Y320 14 +Widow s peak 0.6168091168091163 1.3076846887500044 0.1909802787162617 1.0 0.5485966323608615 4 O15344,Q69YQ0,P29372 3 +Nuclear cataract 0.6174050264090748 1.302394286371472 0.1927816347660362 1.0 0.5530660903186031 5 P08670 1 +Hyporeflexia 0.347412631708769 1.299030042568645 0.1939336192804057 1.0 0.5549579822836754 104 P12235,Q9NZJ7,P03886,Q96BR5,O15269,O14979,O95831,P04792,Q9HC21,Q16637,Q9Y6X9,Q99720,Q8TD16,P54802,Q9BQP7,Q15067,Q8TB36,P35637,O75648,Q15120,Q9BUK6 21 +Polycystic liver disease 0.6130323946735553 1.2899196739834842 0.197078549098403 1.0 0.5625288288704893 4 Q9UGP8 1 +Increased connective tissue 0.6173034403806397 1.2886717403529024 0.1975122310118071 1.0 0.5633046240342382 7 O95831 1 +Elevated circulating follicle stimulating hormone level 0.6127133470647594 1.2884185267374646 0.1976003129793944 1.0 0.5633046240342382 4 P16435 1 +Rectal prolapse 0.6181179406468319 1.2875022632787494 0.1979192812468742 1.0 0.5638572696458041 8 P51812,Q08J23 2 +Myoclonic spasms 0.6121363682358829 1.285703638462545 0.1985465109460982 1.0 0.5641129745918116 4 Q969G3 1 +Hemifacial spasm 0.6121363682358829 1.285703638462545 0.1985465109460982 1.0 0.5641129745918116 4 Q969G3 1 +Hemiparesis 0.6209417039896069 1.2801228061392835 0.2005019490153601 1.0 0.5676270629473794 16 P00403,Q9BVA1,Q969G3,P03886,Q9NZ08,P01889,O60313 7 +Wormian bones 0.6196918761853306 1.2738621738613976 0.2027122660293863 1.0 0.5710151143715275 16 Q96AY3,Q32P28,O95831,Q9Y487,O75844 5 +Abnormal cerebral cortex morphology 0.3283370137815551 1.2713013287255464 0.2036214698316369 1.0 0.5723464470399157 203 Q08J23,O43819,O43924,Q7L7X3,P03886,O76024,P23786,Q9Y619,Q86XL3,Q15392,Q92947,Q9Y487,P00403,Q9NZ01,Q969G3,Q7LGA3,P07437,Q9BVA1,Q96N66,Q9HC21,P42858,Q9Y4P3,Q9Y263,O14936,P40855,P51812,Q02750,Q9H3L0,O43175,O75306,P35637,O75648,Q96PU5,P37268,Q9Y320 35 +Microcytic anemia 0.6136191382776055 1.2711065144851732 0.2036907580882259 1.0 0.5723464470399157 7 Q9UBX3 1 +Abnormality of the pulmonary veins 0.6124249241932916 1.2711006172328805 0.203692855791441 1.0 0.5723464470399157 6 Q15392 1 +Abnormal testis morphology 0.3287065112077045 1.2677364130325612 0.2048920965967269 1.0 0.5746413686132222 195 Q06136,Q08J23,O43924,O96028,P49327,O76024,P21964,P46977,Q9Y619,Q86XL3,P01889,Q9Y487,P53992,P61978,Q15042,Q969G3,Q9BW83,Q13423,Q9NZ08,Q9UBX3,Q7LGA3,P07437,Q06124,P42858,Q9Y4P3,P51114,P48449,P40855,P51809,Q02750,Q9NVI7,O43175,O95470,P38159,O75648,Q96PU5,P37268,P16435 38 +Deep palmar crease 0.6161741616618635 1.265960018487954 0.2055273967556181 1.0 0.5754440494699837 11 P61978,Q9Y487 2 +Hyperconvex nail 0.612520086160931 1.2658652450825576 0.2055613311840856 1.0 0.5754440494699837 7 P51812,O96028,Q9Y619 3 +Abnormality of skull ossification 0.6163608795643518 1.263842713815882 0.2062864866467759 1.0 0.5763099184091414 12 Q9HC21,O75718,Q32P28,O75844,Q15813 5 +Venous thrombosis 0.6163778427675312 1.2594872958576475 0.2078543760732922 1.0 0.5789862008419828 14 O75874,P48735,P40818,Q9NZ08,P01889 5 +Short chin 0.6130651056928389 1.258619654369432 0.208167744454871 1.0 0.5793526469501734 9 Q08J23,O75844 2 +Ureteropelvic junction obstruction 0.6043042634359945 1.2575520842592711 0.208553791433232 1.0 0.5794033927183241 3 Q9UJX6 1 +Limited hip movement 0.615935107116073 1.2572947387599434 0.2086469284184247 1.0 0.5794033927183241 14 Q96AY3,Q9UJX6,Q8TD16,Q7LGA3,O75844 5 +Abnormal circulating fatty acid concentration 0.6145620783069257 1.2490455136890872 0.2116484274685957 1.0 0.584629260801127 15 O75880,O75648,O43772,P23786 4 +Pain 0.3281516012694874 1.2483738256789736 0.2118941897419797 1.0 0.5848175830784461 159 P50402,P12235,Q70HW3,Q9NZJ7,Q14C86,P49327,P21964,P23786,P36551,P01889,Q92804,O15269,P53992,Q969G3,Q8NFH4,Q96HY6,P40818,Q13423,Q9NZ08,O60313,Q14566,Q06124,O75874,Q9Y4P3,Q9UGP8,O14936,Q8N1F7,O75844,P35637,Q15800,P48735,Q9BUK6 32 +Abnormality of reproductive system physiology 0.3334035326473427 1.2472023159615342 0.2123233239448227 1.0 0.5851910217300282 136 P03886,O76024,P01889,Q5JTZ9,P00403,Q16740,Q969G3,Q9BW83,P40818,Q13423,O60313,Q06124,P42858,Q9Y4P3,P48449,Q9UJS0,O75844,P51809,Q9BQP7,O43175,Q9BT22,O95470,Q9BUK6,P31751,P16435 25 +Limb pain 0.6096683501941688 1.2470053024575736 0.2123955533305186 1.0 0.5851910217300282 8 O15269,P36551 2 +Abnormality of metacarpal epiphyses 0.6047956972500627 1.242805706695964 0.2139394391027198 1.0 0.5871636943506625 5 P51812,P16435 2 +Peripheral axonal degeneration 0.4984240292185342 1.2423842480126208 0.2140948246238909 1.0 0.5871636943506625 62 P12235,Q9NZJ7,P48643,P03886,O76024,Q96BR5,P22626,P00403,O15269,Q9Y4W6,P54886,O95831,P04792,Q9BPX6,O60313,Q15813,Q9HC21,Q15067,Q9NVI7,Q8TB36,Q6DKK2 21 +Birth length less than 3rd percentile 0.6027374838485376 1.2414545957161416 0.2144378613049014 1.0 0.5871636943506625 4 Q9Y619 1 +Mild short stature 0.5985597409213533 1.2306016887150553 0.2184718733432555 1.0 0.5956761846086225 3 Q13555 1 +Abnormality of central nervous system electrophysiology 0.334387682385228 1.2295461950943083 0.2188670889845816 1.0 0.5960906982243735 131 P13073,Q9NZJ7,Q08J23,Q9BQE5,P03886,P21964,Q5JTZ9,P00403,Q9NZ01,O75179,O60313,Q9UBX3,O43292,Q96N66,Q9Y263,Q96A33,O14936,P48449,P40855,Q8NHS3,Q02750,Q15067,O43175,P04080,Q3ZCQ8 25 +Aplasia hypoplasia of the femur 0.6094068145319287 1.2249539358172596 0.2205925768839713 1.0 0.5982014103586396 14 O00116,P15260,O95831 3 +Abnormality of the curvature of the vertebral column 0.3015831362614982 1.223874896761626 0.2209994248227782 1.0 0.5989203873306094 275 P50402,Q01105,Q08J23,O96028,Q7L7X3,P21964,P01889,P22626,Q9Y487,O15228,Q96AY3,P53992,P61978,Q15042,P54886,Q969G3,O75718,Q7Z4L5,O95831,Q96HY6,P40818,O75179,Q7LGA3,Q15813,P51648,Q06124,O75874,P08236,Q9Y3Z3,P42858,Q9Y4P3,Q9Y263,Q96A33,O14936,Q9Y6X9,P48449,Q99720,P51812,Q8TD16,O75844,P55795,Q9BQP7,Q02750,Q9NVI7,O43175,Q9BT22,Q9Y285,Q8TB36,P35637,Q9UJX6,P48735,O75648,Q32P28,Q96PU5,Q96CU9,Q9BUK6,Q96J02,P16435,Q92889,Q9Y375,Q9UM00 61 +Areflexia of lower limbs 0.6096107121140459 1.2229618777007136 0.2213440954120185 1.0 0.5991578606738542 18 P12235,Q15067,Q13217,Q15120,Q16637,Q15041,P04792,O60313 8 +Impaired glucose tolerance 0.6021624476993837 1.222376404424634 0.2215653179776961 1.0 0.5993966915519068 6 O76024,P40818 2 +Retinal arteriolar tortuosity 0.6036128313135747 1.2130577052652851 0.2251077589343679 1.0 0.6049854916620133 9 P21964,P53992 2 +Exercise intolerance 0.6009444042537632 1.2111242010826473 0.2258478074571273 1.0 0.6066126747373497 28 P00403,Q9BQP7,P12235,Q9Y2R0,Q9Y285,P13807,P03886,P23786,Q53H12,Q9H2D1,Q92947 11 +Abnormality of the clitoris 0.6068014631695896 1.210366042107903 0.2261384662007373 1.0 0.6070316064125807 15 Q15042,Q9Y619,P40855,P16435,P51809 5 +Hypoparathyroidism 0.6047242371607954 1.206842127987939 0.2274929484890493 1.0 0.6095783108443195 12 P03886,Q08J23,P53992,P21964 4 +Chordee 0.5950901435956981 1.205427170880873 0.2280384375684265 1.0 0.6104408180547009 4 P16435 1 +Abnormal vitamin b12 level 0.5950299009280045 1.205143306293483 0.2281479841339941 1.0 0.6104408180547009 4 Q9H3L0 1 +Oligomenorrhea 0.59844800982531 1.204732361414141 0.228306638835301 1.0 0.6104408180547009 6 P40818 1 +Central hypoventilation 0.5980141294654973 1.2026711846258995 0.2291035889637489 1.0 0.6109355025121349 6 O43819 1 +Gastritis 0.5960461673149366 1.2014197097037205 0.2295884343846408 1.0 0.6111835482498487 5 P49327,Q6PGP7 2 +Proximal tubulopathy 0.6043219740681102 1.1966214275632117 0.2314541447465095 1.0 0.6147105659236997 19 P00403,O43676,O96000,P03886,Q96CU9,Q9Y6M9 6 +Decreased circulating total igm 0.5947365550694791 1.1952236769689122 0.2319996502051835 1.0 0.6157964802560437 5 P49327 1 +Redundant skin 0.6032453318998569 1.1906363877507495 0.2337963602732615 1.0 0.6198354092656411 18 Q02750,P54886,Q9Y4P3,O96000,P51812,Q9Y487 6 +Abnormal tricuspid valve morphology 0.5975110605472237 1.1836327218730676 0.2365584815609818 1.0 0.6264213139808137 9 P21964,P53992 2 +Multiple lentigines 0.5901900802594451 1.182336447318444 0.2370722291710199 1.0 0.6270449160057433 4 Q06124 1 +Decreased circulating copper concentration 0.587905713108163 1.180595786044088 0.2377633384570785 1.0 0.6280310838348612 3 Q14746 1 +Encephalopathy 0.3383032020710809 1.180344778927466 0.2378631151777475 1.0 0.6280310838348612 86 P00403,Q7KZN9,Q15067,Q9NVI7,O43676,Q9NZJ7,O43772,O96000,Q3ZCQ8,P03886,P23786,Q96CU9,Q9Y619,Q92947,Q9UJS0,Q9Y6M9 16 +Bowing of the arm 0.5913046522917134 1.1789858237379562 0.238403820806458 1.0 0.6283905975171031 5 Q32P28 1 +Abnormal circulating igm level 0.598177057905834 1.178272816002936 0.2386878614638317 1.0 0.6285714532401177 11 P49327,P13051,P15260 3 +Skin erosion 0.5927379802889133 1.1776045462491411 0.2389542965943769 1.0 0.6287022853186555 6 O75844 1 +Arrhinencephaly 0.5978934577335892 1.1768904361584038 0.2392392398242342 1.0 0.6290847455588237 11 P21964,P53992 2 +Respiratory insufficiency 0.3237052687460865 1.1751544782271006 0.2399329185674792 1.0 0.6305409119438069 159 P50402,Q70HW3,O43676,Q9NZJ7,Q08J23,O43819,P03886,O76024,P23786,Q9Y619,Q92804,Q96AY3,Q7Z4L5,O95831,O96000,Q9Y263,Q9UGP8,Q16637,P40855,Q9Y6M9,Q9BQP7,Q15067,O43772,Q9BT22,P35637,Q00325,O75648,Q96CU9 28 +Disproportionate short stature 0.5998399667733736 1.1746687082579632 0.2401272830597562 1.0 0.6306839538172038 20 Q03164,O00116,O75718,Q32P28,Q96HY6,Q15392,Q7LGA3 7 +Abnormal size of the clitoris 0.5979550704204134 1.1736666980576689 0.2405285541470854 1.0 0.6310769513641346 12 P51809,Q9Y619,P40855,P16435 4 +Leukoencephalopathy 0.3675319330963317 1.1732464796162154 0.2406969778999217 1.0 0.6310769513641346 82 O43676,Q9NZJ7,Q01105,O96028,Q7L7X3,P03886,Q96BR5,Q5JTZ9,Q5JPH6,P54886,O95831,O60313,Q9Y3Z3,O96000,Q9Y263,Q9Y6X9,Q9Y6M9,O75306,Q9Y285,O75648,Q96CU9 21 +Moderately reduced visual acuity 0.5860259351716748 1.1717716251879933 0.2412887576450533 1.0 0.6322607155268926 3 O60313 1 +Paroxysmal involuntary eye movements 0.599178520926959 1.1710033326426623 0.2415974375774694 1.0 0.6327017147946861 16 P03886,Q9Y6M9,O43676,Q96CU9 4 +Thickened skin 0.3380204663116932 1.1699741658002452 0.2420113653808702 1.0 0.6332839637135094 89 P07437,P50402,O15269,P51648,P16615,O43175,P42166,O95470,Q06136,Q15800,P42167,P48449,P40855,P31751,O75844 15 +Excessive wrinkled skin 0.59454272627425 1.1693168008293071 0.2422760165858046 1.0 0.6332839637135094 9 Q06124,Q9Y487 2 +Increased intramyocellular lipid droplets 0.5885476303442506 1.1659408238573412 0.2436383719045101 1.0 0.6349270036080903 5 Q9BUK6 1 +Megaloblastic anemia 0.5916613717985418 1.160621561126959 0.2457958332050016 1.0 0.6385024900604855 8 Q9H3L0,O43175 2 +Meningocele 0.5893372007032818 1.1552168229408435 0.2480016473007942 1.0 0.6407781762578317 7 P21964 1 +3 methylglutaconic aciduria 0.5864818166722565 1.1415852099434791 0.253626474620678 1.0 0.6487483093730964 7 Q3ZCQ8,Q9NVI7,Q53H12 3 +Melanocytic nevus 0.5904544876420462 1.1406302379144924 0.2540238285094331 1.0 0.6491092490716903 11 Q96AY3,Q92889,Q06124,P21912 4 +Peripheral cyanosis 0.5850731046032613 1.1290123759256607 0.258892612963105 1.0 0.6527933282494235 8 Q9Y3Z3 1 +Thin nail 0.5747330960854111 1.12842308977577 0.2591412809647373 1.0 0.6527933282494235 2 Q9H1A4 1 +Cortical dysplasia 0.5884733472667363 1.1281721723436031 0.2592472137514574 1.0 0.6527933282494235 25 P07437,Q9BVA1,Q08J23,Q96N66 4 +Multifactorial inheritance 0.5860030927818564 1.1281338843930533 0.2592633808667557 1.0 0.6527933282494235 9 P01889,P35611,P10321 3 +Centrally nucleated skeletal muscle fibers 0.5841055045506981 1.124370761392303 0.2608557705865051 1.0 0.6549732356731914 8 P51114,Q9BPX6 2 +Pes cavus 0.3559902170542368 1.1233631526399526 0.2612832924461419 1.0 0.6556814025917381 83 Q08J23,P49589,Q96BR5,P05023,O15269,Q8N2K0,O00429,P54886,O95831,P04792,O60313,Q7LGA3,P42858,Q9Y6X9,Q99720,Q8TB36,O75648,Q15120,Q9BUK6 19 +Decreased activity of mitochondrial complex iv 0.5885691663897752 1.1216620761846678 0.262006146928432 1.0 0.656764017912371 14 Q70HW3 1 +Abnormality of long bone morphology 0.3198553974354343 1.119278441492826 0.2630213700489774 1.0 0.6585762860059673 152 Q08J23,O96028,Q9Y619,P22626,Q9Y487,O15228,Q96AY3,O75718,Q7Z4L5,O95831,Q96HY6,P38435,Q7LGA3,Q15813,P08236,Q06124,O75874,P42858,Q9Y4P3,O14936,P40855,P51812,O75844,Q02750,O00116,Q13126,P48735,O75648,Q32P28,Q96J02,P37268,P16435 32 +Parathyroid adenoma 0.5784904030563784 1.1183621568046436 0.2634123500211527 1.0 0.6588232306022949 5 P48735 1 +Neoplasm of the parathyroid gland 0.5784904030563784 1.1183621568046436 0.2634123500211527 1.0 0.6588232306022949 5 P48735 1 +Amyotrophic lateral sclerosis 0.5888117176525787 1.1178785282761114 0.2636188766192795 1.0 0.6589740859251763 17 P50995,P31483,P35637,Q15165,Q99720,P22626,Q92804 7 +Cerebral dysmyelination 0.5801702106677769 1.1114599482413678 0.2663704206589743 1.0 0.6634982681512509 7 O43175 1 +Shoulder girdle muscle weakness 0.5852198575182599 1.1112534835956829 0.2664592556808884 1.0 0.6634982681512509 12 O14979,P12235,P46976,Q9NZJ7 4 +Bladder neoplasm 0.5766185681871566 1.1095098567965307 0.267210294650241 1.0 0.6642448078937099 5 O96017 1 +Bilateral sensorineural hearing impairment 0.5861434462749538 1.1092616890005993 0.2673173071197636 1.0 0.6642448078937099 23 P00403,Q15067,Q9NZJ7,Q13217,P35637,P03886 6 +Cerebral hypoplasia 0.585481758616477 1.1091891621878265 0.2673485869800731 1.0 0.6642448078937099 13 Q86XL3,Q92947 2 +Feeding difficulties 0.3031865814411295 1.1082063701748042 0.2677727003502854 1.0 0.664754018315541 298 O75880,Q03164,O43676,Q9NZJ7,Q08J23,O43819,O43924,Q7L7X3,P03886,P21964,P23786,O76024,Q9Y619,P46977,Q15392,Q92947,Q9Y487,P53992,P61978,Q9NZ01,Q969G3,Q7Z4L5,O95831,O75179,O60313,Q7LGA3,P53985,P47985,Q06124,Q96N66,Q9Y3Z3,Q9HC21,Q9BUF5,P42858,O96000,Q96A33,O14936,Q9Y263,Q9UGP8,P40855,Q99720,P51812,Q9Y6M9,P55795,Q02750,Q9NVI7,O43175,Q9Y285,P35637,O75648,Q96CU9,Q96J02 52 +Abnormal blood transition element cation concentration 0.5829116245889452 1.1038730233596223 0.2696482224927907 1.0 0.6652391626299994 11 O43819,Q9Y487 2 +Retinal dysplasia 0.5768971469069281 1.1023580513617903 0.2703060409275317 1.0 0.6652391626299994 6 P07437,O43924,O43505 3 +Delayed eruption of permanent teeth 0.5739546451023345 1.0969141315374762 0.2726789306300938 1.0 0.665800400171142 5 Q9UJX6,Q5JRA6 2 +Cerebellar vermis atrophy 0.580794944144855 1.0935617743619663 0.2741472219934324 1.0 0.665800400171142 11 P07437 1 +Abnormal circulating iga level 0.5798611368749396 1.0935223286054108 0.2741645308448719 1.0 0.665800400171142 10 P49327,P13051,Q96J02 3 +Hyperthyroidism 0.5781685254620197 1.090367428788675 0.2755513235294111 1.0 0.6662606304436997 9 P21964,P53992,Q9BUK6 3 +Cns demyelination 0.5807909046352124 1.0895578562454076 0.2759079559993298 1.0 0.6666282157685484 12 P51648,P40855,Q9NZJ7 3 +Agenesis of permanent teeth 0.5651245551601372 1.0835224084523332 0.2785766100460596 1.0 0.6681544983034834 2 Q9ULC3 1 +Abnormal number of permanent teeth 0.5651245551601372 1.0835224084523332 0.2785766100460596 1.0 0.6681544983034834 2 Q9ULC3 1 +Abnormal mitochondrial morphology 0.5792973498247453 1.082243619922151 0.2791442908499921 1.0 0.6681544983034834 12 Q9BQP7,P35637,P46976 3 +Anarthria 0.5739832481850079 1.0819443863216829 0.2792772403654346 1.0 0.6681544983034834 7 Q99720,P54886,P35637 3 +Capillary hemangioma 0.5724583513394172 1.0812879601689336 0.2795690413699074 1.0 0.6681544983034834 6 P16435,Q7LGA3 2 +Peripheral axonal neuropathy 0.5276421213648228 1.0810596727201385 0.2796705705059867 1.0 0.6681544983034834 50 P12235,Q9NZJ7,P48643,P03886,O76024,Q96BR5,P22626,P00403,O15269,Q9Y4W6,P54886,O95831,P04792,Q9BPX6,O60313,Q15813,Q9HC21,Q15067,Q9NVI7 19 +Limb girdle muscular dystrophy 0.5730432017358718 1.0774615711243505 0.2812741099893845 1.0 0.6686194165201245 7 O14979 1 +Aplasia hypoplasia of the ribs 0.5801899300835396 1.0735436499980964 0.2830272649564835 1.0 0.6720779152575719 18 Q03164,Q7Z4L5,Q96HY6,Q9Y619 4 +Elfin facies 0.570657761600829 1.0727441167383844 0.2833859403869847 1.0 0.6725752676799053 6 Q9Y285 1 +Titubation 0.572978356947424 1.071020362790173 0.2841602738545201 1.0 0.6729018050098006 8 Q99720,P35637 2 +Osteoarthritis 0.5741397427328214 1.0709580766055589 0.2841882804304836 1.0 0.6729018050098006 9 P01889,O75844 2 +Increased circulating lactate dehydrogenase concentration 0.5748012061576506 1.064376554015889 0.2871581506863294 1.0 0.6781809868677631 11 P23786,Q5JRX3 2 +Metatarsus adductus 0.5752981237952957 1.0626650585697963 0.287933871910039 1.0 0.6783679878194177 12 Q15392,Q08J23,O96028 3 +Abnormalities of placenta or umbilical cord 0.5764855934790025 1.0617992690909 0.2883268217026247 1.0 0.6785843265868039 14 O75844,P16435,O43175 3 +Abnormality of upper limb joint 0.3301986633404163 1.061228361746252 0.2885861331365267 1.0 0.6788401367673934 95 Q03164,P50402,O96028,P23786,Q9Y619,Q15392,Q96AY3,Q8IZA0,Q15042,P54886,O95831,Q7LGA3,Q06124,Q9Y4P3,Q9Y6X9,O75844,Q02750,O43175,P42892,Q96J02,P37268,P16435 22 +Retinopathy 0.5754837211170963 1.0589783631146308 0.2896096337361789 1.0 0.6794216911825967 25 P07437,P11802,P51648,O75306,Q9UKG1,O43819,O96028,P49327,Q8NHS3,Q9NZ08,P01889,Q92889,Q9Y375 13 +Psychomotor deterioration 0.5714727596479127 1.058115170613838 0.2900029388762752 1.0 0.6794216911825967 9 Q03164,Q9Y487 2 +Sensory neuropathy 0.5705856334442776 1.0513120122972166 0.2931153118423082 1.0 0.683809087241485 29 P00403,O15269,Q15067,P48643,P03886,O95831,Q15041,P22626,O60313 9 +Ovarian carcinoma 0.5580071174377186 1.050297779869629 0.2935812256073382 1.0 0.683809087241485 2 Q8WX93 1 +Extrahepatic cholestasis 0.5580071174377186 1.050297779869629 0.2935812256073382 1.0 0.683809087241485 2 Q8WX93 1 +Peritoneal abscess 0.5580071174377186 1.050297779869629 0.2935812256073382 1.0 0.683809087241485 2 Q8WX93 1 +Functional intestinal obstruction 0.5580071174377186 1.050297779869629 0.2935812256073382 1.0 0.683809087241485 2 Q8WX93 1 +Generalized hyperpigmentation 0.5729632804329915 1.0475485380287912 0.2948466581082007 1.0 0.6849865402544644 13 Q13423,P51648,P40818 3 +Retinal vascular tortuosity 0.5717284751750284 1.041474102174968 0.2976555665688238 1.0 0.6893800814623274 13 P03886,P21964,P53992,Q9Y4P3 4 +Deformed sella turcica 0.558056095180994 1.0405948213998697 0.2980636356787012 1.0 0.6896164301868102 3 P08236 1 +J shaped sella turcica 0.558056095180994 1.0405948213998697 0.2980636356787012 1.0 0.6896164301868102 3 P08236 1 +Abnormality of the posterior pituitary 0.5674722633332355 1.0388610152005695 0.2988693795959141 1.0 0.6903628728775059 9 Q9UHX1,O76024,P42356,Q969G3 4 +Widely spaced incisors 0.5593080702540251 1.036929565144023 0.2997686840782068 1.0 0.6917856933643001 4 Q9BSJ2 1 +Fetal ultrasound soft marker 0.5698739871860357 1.0361291606873704 0.3001418895982488 1.0 0.6919383613397992 12 P16435,Q06124,P61978 3 +Neoplasm of the male external genitalia 0.5666109194860272 1.034717232861546 0.3008009857022991 1.0 0.6931032937424652 9 Q13423,Q01844,P51809 3 +Cerebellar hypoplasia 0.3276564539775295 1.0339550008367815 0.3011572005492597 1.0 0.6934570899609543 105 Q5XKP0,Q15233,Q10713,O43924,Q9Y3E5,P23786,O43684,Q9Y487,P98175,Q69YN2,Q9Y4W6,Q53EZ4,Q15042,P42356,Q969G3,Q8NFH4,P00374,O43505,O43292,P07437,Q9BVA1,Q9HC21,O14936,Q8TD16,P49454,P55795,Q9BQP7,Q9NVI7,O43175,Q9UJX6,Q15058,Q96B26,Q9BUK6,Q9UM00 34 +Neoplasm of the pituitary gland 0.5712280097345815 1.0330637724777345 0.3015740555800272 1.0 0.6934664635199912 15 Q969G3,P48735,P40818,O75874 4 +Abnormal size of pituitary gland 0.5603104185771571 1.032469946516981 0.3018520194764744 1.0 0.6937484085682262 5 Q969G3 1 +Abnormality of the nail 0.3278459478633869 1.031350637800218 0.3023764200165415 1.0 0.6937484085682262 94 Q13555,P16615,Q06136,Q08J23,P04080,Q9Y4P3,Q969G3,O14936,P23786,Q9Y619,Q9Y487,P51812,O75844,P10321 14 +Mixed hypo and hyperpigmentation of the skin 0.5537366548042683 1.03038326665876 0.3028301251685341 1.0 0.6937484085682262 2 P02545 1 +Horizontal pendular nystagmus 0.5537366548042655 1.0303832666587471 0.3028301251685401 1.0 0.6937484085682262 2 P37198 1 +Abnormality of alkaline phosphatase level 0.5712982027501845 1.0284427417817503 0.303741611739136 1.0 0.6949053015778102 18 Q96AY3,Q9UJS0,Q8N511,Q96A33 4 +Motor axonal neuropathy 0.5691819242488801 1.0256616756306756 0.3050510849236272 1.0 0.6971933264456328 14 O15269,Q9Y6X9,O95831,Q96IJ6,P22626,O60313 6 +Meningitis 0.5584728746258314 1.023802806639024 0.3059284244689684 1.0 0.6981364096615902 5 Q9NZ08,P01889 2 +Undetectable light and dark adapted electroretinogram 0.553933784264858 1.021305013892332 0.3071099516821012 1.0 0.6989788208642196 3 P37198,Q15555 2 +Left ventricular systolic dysfunction 0.5597671839488274 1.021121409670898 0.307196920784083 1.0 0.6989788208642196 6 O75844 1 +Increased csf lactate 0.5462389295018822 1.017120773170633 0.309095979303257 1.0 0.6996036921612634 40 P00403,P13073,Q7KZN9,O43676,O75306,Q9HC21,O43819,O96000,Q9P0J0,P03886,O95831,Q96CU9,Q8NCW5,Q9Y6M9 14 +Anencephaly 0.5673693216236511 1.016700684553796 0.3092958400012544 1.0 0.6996036921612634 14 Q9Y3Z3,P21964,P53992 3 +Leiomyosarcoma 0.5588025659301444 1.0165543778088588 0.3093654667134231 1.0 0.6996036921612634 6 P07954,P35222,O60566,P63167,O96017 5 +Reduced tendon reflexes 0.3130063826951096 1.015704095564699 0.309770317140013 1.0 0.6998169520551571 147 P50402,P12235,Q9NZJ7,O43819,P03886,Q96BR5,Q15041,Q96AY3,O15269,P61978,P54886,O14979,O95831,P04792,O60313,Q9HC21,P51114,Q16637,Q9Y6X9,P40855,Q99720,Q8TD16,P54802,Q9BQP7,Q15067,Q9BT22,Q13217,Q8TB36,P35637,O75648,Q15120,Q9BUK6 32 +Pituitary adenoma 0.564342284491708 1.013513948680968 0.3108147369558991 1.0 0.7014732195594579 11 P48735,P40818,O75874 3 +Neurodegeneration 0.563193989564027 1.0107625215095792 0.3121301049896692 1.0 0.7023316940531398 29 Q9Y3Z3,P42858,Q8NHS3,Q6DKK2,Q5JTZ9,Q92804 6 +Back pain 0.5678187509310348 1.0101312266900306 0.3124324232136375 1.0 0.7026611434250819 19 P50402,Q969G3,Q9UGP8,P36551,P01889 5 +Decreased proportion of cd4 positive helper t cells 0.5524469968439045 1.0047121477677194 0.3150354770236678 1.0 0.7064004452466025 4 Q13432 1 +Abnormal proportion of cd4 positive t cells 0.5524469968439045 1.0047121477677194 0.3150354770236678 1.0 0.7064004452466025 4 Q13432 1 +Personality changes 0.56478262030905 0.9986275310954152 0.3179751582464267 1.0 0.7105176193438996 16 P03886,P42858 2 +Neoplasm of the oral cavity 0.5594044656632693 0.9945708332580246 0.319945038941166 1.0 0.71222877131329 10 O43924,Q969G3 2 +Sensory axonal neuropathy 0.5615874279617796 0.9916434223054292 0.3213714993786225 1.0 0.71222877131329 13 P48643,P22626,Q15067,O95831 4 +Abnormal sternal ossification 0.5495970986737877 0.9913461293263984 0.3215165954110799 1.0 0.71222877131329 4 Q9Y619 1 +Abnormal circulating cholesterol concentration 0.5589414652134186 0.9874574295430016 0.3234184424683124 1.0 0.71222877131329 29 P50402,Q9NVI7,Q9NZJ7,P42858,Q8N511,Q15800,P37268,Q9UJS0,Q15392 9 +Pathologic fracture 0.5598679400350848 0.9872528987150988 0.323518674944427 1.0 0.71222877131329 12 O15269 1 +Abnormality of mouth size 0.3230228964147582 0.9870058151988006 0.3236397878077697 1.0 0.71222877131329 111 Q01105,Q08J23,P21964,Q9Y619,Q15392,Q9Y487,P53992,Q15042,P54886,P31939,Q969G3,Q7LGA3,P07437,P42858,Q9Y4P3,P51812,O75844,P55795,Q02750,Q9NVI7,O75648,P16435 22 +Cryptorchidism 0.3123694642798619 0.9822480845935352 0.3259776438644726 1.0 0.7140524900996957 165 Q08J23,O43924,O96028,P21964,P46977,Q9Y619,Q86XL3,Q9Y487,P53992,P61978,Q15042,Q969G3,Q9BW83,Q13423,Q7LGA3,P07437,Q06124,P42858,Q9Y4P3,P51114,P48449,P40855,P51809,Q02750,Q9NVI7,O43175,O95470,O75648,Q96PU5,P37268,P16435 31 +High hypermetropia 0.5541393027973818 0.9809101357473604 0.3266370587325489 1.0 0.7140800404808342 8 P68371 1 +Periorbital fullness 0.5616082430883179 0.9793785398189582 0.3273929766105321 1.0 0.714556971226958 18 P07437,O75179,P40855,P51812,Q7LGA3 5 +Posteriorly rotated ears 0.3232154479036924 0.9709116943899124 0.3315922541656506 1.0 0.7181577556581391 94 Q02750,P07437,Q06124,Q08J23,Q15042,O43924,Q9Y4P3,P16435,Q9BW83,Q9Y263,O96028,P23786,Q9Y619,Q96J02,P40855,P37268,Q15392,Q7LGA3 18 +Uveitis 0.5500610248033163 0.9681121320834084 0.3329883714824744 1.0 0.7201432774815317 7 P49327,P01889,Q92889 3 +Synovitis 0.5416693489522278 0.964035942888632 0.3350279060104992 1.0 0.7220678820936685 3 Q06124 1 +Delayed cranial suture closure 0.5569374069646623 0.9603949315930236 0.336856488012311 1.0 0.7236473743906033 25 Q08J23,P54886,O75718,Q32P28,P40855,O75844,P51812,P16435,Q9Y487 9 +Acute lymphoblastic leukemia 0.5529396808947091 0.958201888083585 0.3379609653452453 1.0 0.7256741642739498 11 Q9BYW2,Q08J23,Q9UJX6,O43684,O96017 5 +Thickened nuchal skin fold 0.5501259505649726 0.955575315079612 0.3392868377763949 1.0 0.7271354150538335 9 Q06124,P61978 2 +Osteomyelitis 0.5539004055834029 0.9539569096138564 0.340105454616898 1.0 0.7279952197657575 13 O15269,P15260 2 +Abnormal circulating methionine concentration 0.5462593551204575 0.9500879641607736 0.3420675583011303 1.0 0.7279952197657575 7 P55263,Q9H3L0,Q9UJS0 3 +Lipoma 0.5427901719646134 0.950002640548084 0.3421109109083369 1.0 0.7279952197657575 5 Q9BUK6,P21912 2 +Abnormal size of the palpebral fissures 0.3479165879231402 0.9487086611334252 0.3427688077419493 1.0 0.7280202716743476 82 Q13555,P07437,Q03164,Q02750,P61978,Q08J23,P42858,Q9Y4P3,O75648,Q9Y619,P51812,Q7LGA3,P55795,O75844 14 +Partial agenesis of the corpus callosum 0.5484478366939852 0.9475405592648014 0.3433633988043969 1.0 0.7288355006129262 9 Q15392 1 +Abnormal circulating porphyrin concentration 0.5370776254460996 0.9426524806544392 0.3458586867436861 1.0 0.7321797815798576 3 P36551 1 +Pace of progression 0.3100221125844524 0.9407624370246076 0.3468266144044276 1.0 0.7329467898079085 144 P50402,P12235,Q5XKP0,P49736,Q10713,Q9Y3E5,Q96BR5,P05023,Q5JTZ9,Q9NXN4,Q8N2K0,Q69YN2,Q9Y4W6,P31483,O00429,P54886,O14979,Q9P0J0,O95831,P04792,O60313,Q15813,Q9NR28,Q9BUF5,Q16637,Q9Y6X9,Q8NHS3,Q99720,P55263,Q8NBU5,Q8N1F7,Q9Y6M9,P46976,Q8NCW5,Q9BQP7,Q02750,Q6IA86,Q14671,P54802,Q9BW27,O95470,Q8TB36,Q9UBS4,Q13126,O95140,Q15120,Q12769,Q9NRG9 48 +Cortical myoclonus 0.5341637010676166 0.9393955673491324 0.3475276880007554 1.0 0.7329467898079085 2 Q9Y4G8 1 +Reduced antigen specific t cell proliferation 0.5341637010676088 0.939395567349097 0.3475276880007736 1.0 0.7329467898079085 2 P17812 1 +Abnormal t cell proliferation 0.5341637010676088 0.939395567349097 0.3475276880007736 1.0 0.7329467898079085 2 P17812 1 +Membranoproliferative glomerulonephritis 0.5341637010676075 0.9393955673490908 0.3475276880007767 1.0 0.7329467898079085 2 Q03252 1 +Neck muscle weakness 0.5511125013415118 0.9365181247747322 0.3490064851021688 1.0 0.734445332338343 14 Q99720,P35637,P46976 3 +Large basal ganglia 0.5493379197278152 0.9359619848855174 0.349292760932437 1.0 0.734531512668147 12 Q08J23,Q96N66 2 +Quadriceps muscle weakness 0.5377080132951824 0.9357150564355466 0.3494199163879536 1.0 0.734531512668147 4 P12235 1 +Misalignment of incisors 0.5393658710366858 0.9339386761222812 0.3503355268704602 1.0 0.7361129228928505 5 Q96N67,Q8WVM7,Q99496,Q9BSJ2 4 +Increased serum pyruvate 0.5497749292148623 0.9326099543134212 0.351021391912937 1.0 0.7365239354523311 28 Q70HW3,O43676,O96000,Q5JRX3,P03886,O95831,Q96CU9,Q9Y6M9 8 +Moderate global developmental delay 0.5452349118865176 0.9321708268983387 0.351248249474037 1.0 0.7366569848206072 9 O95831 1 +Trichorrhexis nodosa 0.5342741389046897 0.9296151984607685 0.3525703554052763 1.0 0.7374985334651962 3 Q6PGP7 1 +Arthropathy 0.5382941919587529 0.9289156718689778 0.3529327904708821 1.0 0.7374985334651962 5 O15269 1 +Basal ganglia gliosis 0.5414171692936269 0.9271664645358532 0.3538401116775982 1.0 0.7385983367508181 7 O43819 1 +Epiphyseal stippling 0.5452895025313306 0.9265864651442705 0.3541412849362801 1.0 0.7386000792261984 10 P38435,O00116,P40855 3 +Low alkaline phosphatase 0.5331609213235808 0.9244424742609508 0.3552559891539497 1.0 0.7405822123574706 3 Q92643 1 +Giant platelets 0.5306049822063962 0.9229187597523956 0.3560495435426394 1.0 0.7415505049661163 2 Q14739 1 +Oral ulcer 0.5402728186258132 0.9217558338132562 0.3566559497459669 1.0 0.7420521086386088 7 Q9NZ08,P01889 2 +Intrauterine growth retardation 0.3086869119464007 0.9177328080070244 0.3587587671008461 1.0 0.7447838615032304 175 O75880,Q03164,O43676,Q08J23,O43924,O96028,P03886,P21964,P49589,Q9Y619,Q15392,Q9Y487,P53992,Q15042,P54886,Q969G3,Q6PGP7,P47985,Q06124,O96000,Q9UJS0,Q9Y6M9,O75844,O43175,Q9BT22,O75306,Q96CU9,P37268,Q6P4A7 29 +Aphthous ulcer 0.537261886863355 0.9149062913640228 0.3602408269657411 1.0 0.7471722996477658 6 Q9NZ08,P01889 2 +Abnormal circulating igg level 0.5447495717443781 0.9136721747217876 0.3608891291749065 1.0 0.7480015908439969 12 P49327,P13051,P15260 3 +Fetal distress 0.5489593082557573 0.9134666834699752 0.3609971482204228 1.0 0.7480015908439969 20 Q9NVI7,O43676,O96000,P03886,Q96CU9,Q9Y6M9 6 +Anodontia 0.5307091287105238 0.913058653614198 0.3612116943224155 1.0 0.7480015908439969 3 P51812 1 +Delusions 0.5480638916927774 0.912882165748563 0.3613045181423078 1.0 0.7480015908439969 17 Q9NZJ7,P42858,Q9BQE5,P21964,Q9UJS0 5 +Hip contracture 0.5443727231798107 0.9118433201659129 0.3618512022365641 1.0 0.7485176023845916 12 Q96AY3,Q8TD16,Q7LGA3,Q9UJX6 4 +Cerebellar atrophy 0.316010175954742 0.9112296522447156 0.3621743834501711 1.0 0.7485176023845916 118 P13073,P12235,P49589,P46977,Q96BR5,Q5JTZ9,Q9NXN4,Q9Y4W6,O60313,O43292,Q15813,P07437,Q9BVA1,P42858,Q9Y263,O14936,O75312,Q8NHS3,Q9BQP7,Q9NVI7,Q9BT22,Q13217,Q5JRX3,O75648,Q96CU9,Q6DKK2,Q9Y320 27 +External ophthalmoplegia 0.546584082133751 0.9108315050117394 0.3623841598409538 1.0 0.7485176023845916 15 Q9BQP7,P00403,P12235,Q07021,P03886,O60313 6 +Abnormal femoral neck head morphology 0.5303952085697804 0.9093046912696536 0.3631893149818452 1.0 0.7494937008347878 39 Q96AY3,P15260,Q96A33,O75718,O95831,Q96HY6,Q9Y619,O75844,P51812,Q9Y487 10 +Abnormal csf protein level 0.5399281624691181 0.8953444142024901 0.3706030049264619 1.0 0.760868600163683 11 P03886,Q9NZJ7 2 +Spontaneous abortion 0.524199288256225 0.8933262925669491 0.3716824617210574 1.0 0.7617884742959554 2 P50570 1 +Portal vein thrombosis 0.5238434163700969 0.8916849486255904 0.3725618232816035 1.0 0.7619169573700062 2 P35222 1 +Splanchnic vein thrombosis 0.5238434163700969 0.8916849486255904 0.3725618232816035 1.0 0.7619169573700062 2 P35222 1 +Epigastric pain 0.5238434163700969 0.8916849486255904 0.3725618232816035 1.0 0.7619169573700062 2 P35222 1 +Dyspnea 0.315883961487416 0.8866353850872726 0.3752752365071687 1.0 0.7656702086635625 89 Q9BQP7,Q9NZJ7,P35637,Q00325,P03886,O75648,P23786,O95831,Q9Y619,P01889,Q92804,P46976,O75844 13 +Difficulty standing 0.5287351096796706 0.8842164750510948 0.376579366434814 1.0 0.767636003854232 5 O43292 1 +Abnormal pulmonary valve morphology 0.5374974812482913 0.8836407209846542 0.3768901896661729 1.0 0.7677926111362205 11 P21964,P53992 2 +Abnormal greater sciatic notch morphology 0.526210264887881 0.8821655396233028 0.3776872942377483 1.0 0.7688512353791922 4 Q96HY6 1 +Abnormality of hair growth 0.5261249901886627 0.8817694869868051 0.3779014754454137 1.0 0.7689283257742687 4 P04080 1 +Laryngeal cleft 0.5213523131672624 0.8802039958245746 0.3787488092342439 1.0 0.7689283257742687 2 Q69YQ0 1 +Diminished ability to concentrate 0.5213523131672622 0.8802039958245743 0.3787488092342441 1.0 0.7689283257742687 2 Q96RR1 1 +Nocturnal seizures 0.5213523131672498 0.8802039958245177 0.3787488092342748 1.0 0.7689283257742687 2 Q9NQX3 1 +Acute coronary syndrome 0.5414429734552658 0.8798065311531647 0.378964125955695 1.0 0.7690190525359377 17 Q06124,Q9Y4P3,Q9NZ08,P01889,O75844 5 +Hypoplastic nipples 0.5348609154471781 0.8765958769883934 0.3807061794346631 1.0 0.770877368233994 10 P07437 1 +Visual impairment 0.2972196324795151 0.8733096475336728 0.382494323449847 1.0 0.7730606232560632 243 P12235,O43676,Q9NZJ7,Q01105,Q08J23,O43819,P36404,Q7L7X3,P49327,P03886,P01889,P00403,Q5JPH6,Q9Y4W6,Q15042,Q9Y287,Q9NZ01,Q969G3,Q13432,P68371,O95831,P40818,Q9NZ08,O60313,Q7LGA3,O43292,Q9BVA1,Q96N66,P42858,Q9Y4P3,O96000,Q96A33,O14936,P48449,P40855,Q8NHS3,Q9Y6M9,O43175,O75306,Q9H061,O75648,Q96CU9,P37268,Q6P4A7 44 +Infertility 0.5352782254302145 0.8729672494017129 0.3826809290798802 1.0 0.7730606232560632 11 P51809,Q06124,P40818 3 +Abnormal internal genitalia 0.3155863765785084 0.8723562485264152 0.3830140607345882 1.0 0.7730606232560632 107 O96028,P49327,P21964,P57740,Q5JTZ9,O43684,P53992,Q15437,O95202,Q16740,O15160,Q9BW83,P40818,O60216,P13051,Q8WWQ0,Q06124,O75874,Q9BYW2,Q01844,Q9Y4P3,P21912,O75312,P51812,Q9NR50,O75844,O96017,P51809,O43175,Q15058,P48735,P31751,P16435,Q92889 34 +Short attention span 0.3137032001885682 0.8710242185624977 0.3837409295714269 1.0 0.7734885373785426 115 P00403,Q03164,Q9BVA1,P53992,Q96N66,Q9NZJ7,Q08J23,P42858,Q9NZ01,P03886,O75648,P21964,O75179,P51812,Q7LGA3,P55795 16 +Abnormal blistering of the skin 0.5382260337556442 0.8696237935791573 0.3845060304701093 1.0 0.7738773385012901 15 P49327,P01889,Q9NZ08,Q06136 4 +Abnormal pericardium morphology 0.5318927353697932 0.8685700924809692 0.3850823187311289 1.0 0.7743577672436563 9 Q9NZ08,P47985,P01889 3 +Motor delay 0.306103094650619 0.8683494793671839 0.3852030428578383 1.0 0.7743577672436563 193 Q03164,Q08J23,O43819,P03886,Q9Y487,P00403,P61978,Q9NZ01,O75179,Q9BPX6,O60313,P07437,Q9BVA1,P47985,Q96N66,P42858,O14936,P51114,Q99720,P51812,P35637,Q3ZCQ8,O75648,Q15120,Q96J02,Q9BUK6,P16435 27 +Polycystic kidney dysplasia 0.5361553311234337 0.8673658747328601 0.3857415733856906 1.0 0.774404129732431 13 P21964,P23786 2 +Abnormality of pelvic girdle bone morphology 0.3117318105888411 0.8666487066264783 0.3861345177723569 1.0 0.7748478502226237 126 O96028,Q9Y619,P01889,Q9Y487,O15228,Q96AY3,Q8IZA0,P61978,P54886,O75718,Q7Z4L5,O95831,Q96HY6,Q7LGA3,P08236,P15260,P42858,Q9Y4P3,Q96A33,Q8TD16,P51812,O75844,Q9NVI7,O75648,P16435,Q92889 26 +Abnormal cartilage morphology 0.5336962868457483 0.8653663974362249 0.3868377181452027 1.0 0.7754991938379908 11 P48735,Q7LGA3,Q06124 3 +Asymmetric growth 0.5305156112197685 0.862029180186987 0.3886714605252725 1.0 0.7771704847326546 9 P07437 1 +Psychosis 0.5346540827288299 0.8595783162381014 0.3900215321287472 1.0 0.7787266656273815 30 P00403,Q6DKK2,P51812,Q9Y287,Q5JRX3,O15118,O76024,P03886,P36551,P40818,Q9UJS0 11 +Aplasia hypoplasia of the cerebellum 0.3117765597589318 0.8478472512806821 0.3965230442350504 1.0 0.7883234937659341 116 Q5XKP0,Q15233,Q10713,O43924,Q9Y3E5,O96028,P23786,O43684,Q9Y487,P98175,Q69YN2,Q9Y4W6,Q53EZ4,P53007,Q15042,P42356,Q969G3,Q8NFH4,P00374,O60216,O43505,O43292,P07437,Q9BVA1,Q9HC21,O14936,Q8TD16,P51812,P49454,P55795,Q9BQP7,Q9NVI7,O43175,Q9UJX6,Q15058,Q96B26,Q9BUK6,Q9UM00 38 +Abnormal delivery 0.5357028838852557 0.8453373657819622 0.3979225042220382 1.0 0.7907569340955584 21 O75844,O60313,Q9Y619,Q9Y487 4 +Aplasia cutis congenita over the scalp vertex 0.513167259786468 0.8425934519633829 0.399455854481513 1.0 0.7927554100168116 2 Q15149 1 +Congenital localized absence of skin 0.513167259786468 0.8425934519633829 0.399455854481513 1.0 0.7927554100168116 2 Q15149 1 +Round face 0.5327801176585781 0.8395330011744614 0.4011702783361723 1.0 0.7954573006868143 16 Q03164,Q32P28,P40818 3 +Abnormal epiphyseal ossification 0.5293915808311623 0.8345556989167678 0.4039679142535144 1.0 0.7985610988692113 13 P38435,O00116,Q96HY6,P40855 4 +Restrictive cardiomyopathy 0.5113879003558613 0.8344420748062568 0.4040319159874213 1.0 0.7985610988692113 2 O95235 1 +Abnormality of coordination 0.2890942963988176 0.8334363233231558 0.4045986962168102 1.0 0.7985610988692113 281 P12235,O43676,Q9NZJ7,Q01105,O43819,O43924,O96028,O15118,P49327,P03886,O76024,P49589,Q96BR5,Q9Y619,P01889,Q5JTZ9,Q92947,Q9Y487,P00403,Q9NXN4,Q9Y4W6,Q9Y287,P54886,Q969G3,O95831,Q9NZ08,Q9BPX6,O60313,O43292,P07437,Q9BVA1,Q7KZN9,P42858,Q9Y4P3,O96000,O14936,P40855,Q8NHS3,Q99720,Q9Y6M9,P55795,Q9H3L0,O14949,Q15067,Q9NVI7,O75306,O95470,Q13217,P04080,P35637,Q5JRX3,Q96CU9,Q9BUK6,Q6DKK2,Q6P4A7 55 +Biconcave vertebral bodies 0.5196403619394729 0.8324446025898014 0.405158034963335 1.0 0.7985610988692113 6 Q96AY3 1 +Abnormal epidermal morphology 0.5308181209323176 0.8298562615621126 0.4066200566303113 1.0 0.7994790838343147 16 P01889,P16615,O75844,Q06136 4 +Ventricular tachycardia 0.5282448561446315 0.8290059074919196 0.407101064433049 1.0 0.7994790838343147 13 O43772,P23786 2 +Abnormally folded helix 0.5305645071403942 0.8286062476390248 0.4073272515721491 1.0 0.7995748792838311 16 P21964,P23786 2 +Broad alveolar ridges 0.5099644128113848 0.8279278388180183 0.4077113679526691 1.0 0.7996323478514709 2 P21281 1 +Abnormality of prenatal development or birth 0.3034528010306256 0.8273650694516362 0.4080301728184821 1.0 0.7999095210495427 205 Q70HW3,O43676,O96028,O15118,P03886,P21964,P23786,Q9Y619,Q9Y487,P53992,P61978,O75718,O60313,Q7LGA3,Q7KZN9,Q06124,Q9HC21,Q9Y4P3,O96000,P51114,Q16637,P40855,Q9Y6M9,O75844,Q02750,Q9NVI7,O43175,O43772,Q9BT22,Q9Y285,O75306,Q96CU9,P16435 33 +Pectus excavatum 0.3963108772841835 0.8215568510645032 0.411329155483414 1.0 0.8050305718677737 72 Q03164,P50402,Q9Y4R8,Q08J23,Q9Y487,P61978,P54886,P42356,Q9NSD9,O75718,Q7LGA3,O60216,P07437,Q06124,Q9UHX1,Q9Y4P3,Q96A33,P51812,Q02750,Q9UJX6,Q96J02,Q9BUK6 22 +Abnormality of the supraorbital ridges 0.5305495253170771 0.8213084764744831 0.4114705806736247 1.0 0.8050305718677737 19 Q02750,Q08J23,P38159,P40855,P51812,P16435,Q6PGP7 7 +Contractures of the joints of the upper limbs 0.4533224926759105 0.8211945041665867 0.4115354864839917 1.0 0.8050305718677737 60 Q96AY3,P50402,Q8IZA0,O43175,P42892,P37268,Q15042,P54886,P35637,P16435,P23786,Q9Y6X9,Q9Y619,Q99720,Q15392,Q7LGA3,O75844 17 +Submucous cleft of soft and hard palate 0.5303093974092101 0.8187070877974779 0.4129535517842244 1.0 0.8073925120621859 20 Q02750,O43175,Q08J23,Q9Y619,Q15392,Q7LGA3,O75844 7 +Abnormality of femur morphology 0.4564821973669929 0.814530877577922 0.4153408906804383 1.0 0.8096122935276763 59 Q96AY3,O00116,P15260,Q9NZJ7,Q96A33,O75718,Q32P28,O95831,Q96HY6,Q9Y619,O75844,P51812,P16435,Q9Y487 14 +Abnormal iliac wing morphology 0.5204762484881886 0.8145050558178818 0.4153556770597046 1.0 0.8096122935276763 9 O95831 1 +Poor eye contact 0.5221103770274259 0.8141815171029467 0.4155409722050005 1.0 0.8096122935276763 34 P03886,Q9Y6M9,O43676,Q96CU9 4 +Entropion 0.5217110201192282 0.8139492434594712 0.4156740286716314 1.0 0.8096122935276763 10 O75844 1 +Abnormal lung lobation 0.5234932998990678 0.8110538598993207 0.4173347411858477 1.0 0.8113493396083064 12 P53992,Q9UHX1,Q14739,P21964,O60566,O43684 6 +Abnormal metabolic brain imaging by mrs 0.5261718579912043 0.8105119704465019 0.4176459879945131 1.0 0.8113493396083064 15 P00403,Q9NZJ7,O75306,Q14353,O00429,O43819,P03886 7 +Pseudoepiphyses of the metacarpals 0.5105275851362895 0.8096602268932103 0.418135483059936 1.0 0.8119502895954898 4 P51812 1 +Papilledema 0.528246444117306 0.8082848919596642 0.4189265976998606 1.0 0.8125599806728984 20 P47985,P42858,Q969G3,O75648 4 +Broad foot 0.5176683419060196 0.808174169914883 0.4189903250685192 1.0 0.8125599806728984 8 O95831 1 +Abnormal femoral neck morphology 0.5230296558911395 0.8063298911647039 0.4200526596878768 1.0 0.8126506690135128 32 Q96AY3,Q96A33,O95831,Q96HY6,Q9Y619,O75844,P51812,Q9Y487 8 +Premature graying of hair 0.5156533939396494 0.8061076740016807 0.4201807671423081 1.0 0.8126506690135128 7 Q13126 1 +Opsoclonus 0.5049822064056966 0.8051785851108393 0.4207166323371645 1.0 0.8126506690135128 2 O60333 1 +Saccadic oscillation 0.5049822064056966 0.8051785851108393 0.4207166323371645 1.0 0.8126506690135128 2 O60333 1 +Hypometric saccades 0.5049822064056932 0.805178585110824 0.4207166323371734 1.0 0.8126506690135128 2 P49959 1 +Spontaneous recurrent epistaxis 0.5049822064056849 0.8051785851107862 0.4207166323371951 1.0 0.8126506690135128 2 P35579 1 +Rhabdomyolysis 0.5221444500362857 0.8045854696720417 0.4210589298064939 1.0 0.8126506690135128 12 P23786 1 +Abnormal corpus callosum morphology 0.2931694412981584 0.8013802068026387 0.4229115702376154 1.0 0.8156022452122089 247 Q03164,Q9NZJ7,Q01105,Q08J23,O43924,O96028,Q7L7X3,P03886,P23786,Q86XL3,Q15392,P00403,Q5JPH6,P61978,Q9NZ01,Q969G3,O95831,O60313,Q9UBX3,Q7LGA3,P07437,Q9BVA1,Q96N66,Q9Y3Z3,Q9HC21,P42858,Q9Y263,Q96A33,O14936,P48449,P51812,Q9NVI7,O43175,O75648,Q96PU5,P37268,Q9Y320 37 +Abnormal astrocyte morphology 0.5249137935663628 0.8008070686164658 0.4232433462184048 1.0 0.815892968950535 16 O75874,Q9BYW2,Q9UJX6,P48735,O95831,O96017 6 +Polycythemia 0.5035587188611987 0.7986939488194901 0.4244678963958059 1.0 0.8175541919042296 2 P07954 1 +Abnormal circulating carbohydrate concentration 0.519198870971056 0.7977559005109278 0.4250121572091294 1.0 0.8182527947635825 34 Q70HW3,O43676,O96000,Q5JRX3,P03886,O95831,Q96CU9,Q9BWD1,Q9UJS0,Q9Y6M9 10 +Abnormality of the fontanelles or cranial sutures 0.3089161051389564 0.797427247518959 0.425202939882551 1.0 0.818270559372612 89 Q96AY3,P53992,P61978,Q9BT22,Q08J23,O75718,Q32P28,O95831,P21964,Q9Y619,Q9Y487,P51812,P16435,O75844 14 +Abnormality of subcutaneous fat tissue 0.5225052815578951 0.796722269055983 0.425612347716414 1.0 0.818708856661493 14 O75844,Q9Y487 2 +Steppage gait 0.5251905783278839 0.794440172793013 0.4269392249838257 1.0 0.8204520565965195 19 O15269,P31483,Q8TB36,O43819,Q15120,Q96BR5,P05023,P04792 8 +Impaired pain sensation 0.5242042797389422 0.7942246122449136 0.4270646826659496 1.0 0.8204520565965195 17 P04792,O15269,O95831,P61978 4 +Increased urine proteinogenic amino acid derivative level 0.5024911032028371 0.7938350895706321 0.4272914419473324 1.0 0.8205083120779384 2 Q9NQX3 1 +Bulbar palsy 0.5192835958953724 0.7908865011819952 0.4290102262514845 1.0 0.8210404160357052 12 P31483,P35637,Q9Y263,P43243 4 +Abnormality of metacarpophalangeal joint 0.5038804114218232 0.7894845241263958 0.4298288714249729 1.0 0.8210404160357052 3 P16435 1 +Bilateral cryptorchidism 0.5162122363634064 0.7879096660802918 0.4307495467706428 1.0 0.8217966016722501 10 P37268,P48449,O43924 3 +Malignant neoplasm of the central nervous system 0.5241409067779608 0.7875854583333529 0.4309392232801126 1.0 0.8217966016722501 20 P07437,Q06124,O75874,Q9UJX6,P21912,P48735 6 +Increased circulating prolactin concentration 0.511512959637421 0.7868326527480879 0.4313798361295218 1.0 0.8219759520714963 7 Q9BUK6 1 +Decreased head circumference 0.2856360430281593 0.7866126042854404 0.4315086785622846 1.0 0.8219759520714963 394 Q03164,O43676,Q9NZJ7,Q06136,Q08J23,Q7L7X3,P03886,P21964,P23786,P46977,Q9Y619,Q86XL3,Q15392,Q9Y487,P53992,P61978,Q16740,Q9NZ01,Q969G3,O75179,Q8NFH4,Q9BPX6,Q7LGA3,P07437,Q9BVA1,Q7KZN9,P51648,Q96N66,Q9Y3Z3,Q9HC21,P42858,Q9Y4P3,O96000,Q96A33,O14936,Q9Y263,P48449,Q99720,P51812,Q9Y6M9,P55795,Q9BQP7,O43175,O43772,O95470,Q9BT22,Q9Y285,P35637,Q15800,O75648,Q96CU9,P16435 52 +Cerebral edema 0.5126206777222545 0.784550375728724 0.4327172350505031 1.0 0.822448265733246 8 Q9UJS0,P23786 2 +Genu varum 0.5140160516980472 0.7840910625254807 0.4329866792955794 1.0 0.822448265733246 9 Q9Y619 1 +Spastic diplegia 0.5236408902128981 0.7833940538163972 0.4333957468640912 1.0 0.822448265733246 22 P51648,Q9NZJ7,Q15042,P35637,Q99720,Q92947 6 +Late onset 0.5132183708498418 0.7803457553956458 0.4351873875119372 1.0 0.825153367907573 9 P18031,P31483,P31751,O76024,Q9Y6M1 5 +Lack of skin elasticity 0.519842245049292 0.7796544554593042 0.4355942935720183 1.0 0.8255577770970763 15 O75844,P40818 2 +Sensorimotor neuropathy 0.5212608097812429 0.779050120822044 0.4359501907013627 1.0 0.8255577770970763 28 P00403,Q8N2K0,Q9Y2R0,Q9NZJ7,Q9Y4W6,Q13217,P03886,Q15120,O95831,P05023,O60313 11 +Increased intracranial pressure 0.5209439821420311 0.7781444040126134 0.4364838878123689 1.0 0.8262212861698223 17 Q9NZ08,P01889,Q969G3,Q9NZJ7 4 +Lumbar scoliosis 0.5032051282051351 0.7760715962943031 0.4377067133903507 1.0 0.8274933545513049 4 P27635,O95340,P21281 3 +Astrocytoma 0.5117153283042091 0.7732949557984283 0.4393478403428783 1.0 0.8286506373311883 9 P48735,Q9UJX6,O75874,O96017 4 +Lymphocytosis 0.500166099225205 0.7725542560338645 0.4397862254579017 1.0 0.8286506373311883 3 P49327 1 +Thoracic kyphosis 0.5170655901455778 0.7704139070520627 0.4410544064922532 1.0 0.8302230239237915 14 O95831 1 +Neuronal loss in central nervous system 0.5147808859470299 0.7693843902030647 0.4416651524993247 1.0 0.8307950093132122 12 O43819,P42858,P35637,Q9NZJ7 4 +Abnormal csf metabolite level 0.4865357861756092 0.7678272488459709 0.4425898236013754 1.0 0.8318400062432856 48 P00403,P13073,Q7KZN9,O43676,O75306,Q9HC21,Q9Y3Z3,O43819,O96000,Q9P0J0,P03886,O95831,Q96CU9,Q8NCW5,Q9Y6M9 15 +Abnormality of the parathyroid gland 0.5194433210058017 0.7639748402763152 0.4448822360679285 1.0 0.834925363725503 20 P00403,P53992,Q08J23,P48735,P03886,P21964 6 +Large for gestational age 0.5081757967154122 0.7638235077829006 0.4449724259304766 1.0 0.834925363725503 8 P31751,Q9UKG1,Q9UM00 3 +Abnormal pleura morphology 0.517276144007589 0.763406367603572 0.445221083588867 1.0 0.8350442878630976 16 Q02750,Q06124,P49327,Q9NZ08,P01889 5 +Avascular necrosis 0.5186253062683822 0.7616602368071805 0.4462628132239068 1.0 0.8356071870378678 19 Q06124,P40818,Q9Y619,Q9NZ08,P01889,O75844 6 +Hypointensity of cerebral white matter on mri 0.5042572245708834 0.7612092899413366 0.4465320703313362 1.0 0.8357641366209853 6 Q9Y3Z3 1 +Hyperlipidemia 0.5188907171381428 0.7602125320261827 0.4471275552196827 1.0 0.8358792754223066 25 P50402,Q9Y285,O95470,P23786,P31751,O75844 6 +Ambiguous genitalia 0.5152953666049098 0.7575774747828123 0.4487039691728161 1.0 0.8359139020746202 15 Q15392,P16435,O43175 3 +Abnormality of immune serum protein physiology 0.5049418087897892 0.7563696813828737 0.4494275805379479 1.0 0.8359761062668309 7 Q9Y3Z3 1 +Elevated hemoglobin a1c 0.4986276375821344 0.7551751640861362 0.4501438884299951 1.0 0.8367702623970572 4 Q9UKG1,Q969M3 2 +Wide cranial sutures 0.5045869073039143 0.754729160977348 0.4504115057855027 1.0 0.8367702623970572 7 O75718,O75844 2 +Abnormality of hepatobiliary system physiology 0.427379065749245 0.7513606823933265 0.4524356182175639 1.0 0.8391470499203953 64 Q9BT22,O75306,O43772,O43819,Q8N511,Q96A33,P03886,O75648,P23786,Q9Y619,P40855,P55263,Q96J02,P01889 14 +Adrenal insufficiency 0.5171012864241419 0.75008512822711 0.4532034357990473 1.0 0.8395346835784243 24 O95470,Q969G3,P40855,Q13423,P16435 5 +Multiple prenatal fractures 0.5034355108952625 0.7494103786510914 0.4536098973812112 1.0 0.8399424024228098 7 Q32P28 1 +Inflammation of the large intestine 0.5069748272525805 0.7444132326094741 0.4566265159426592 1.0 0.8437948779637413 10 P49327,P01889,Q6PGP7 3 +Shield chest 0.4980475984883156 0.742442939879274 0.4578190112886191 1.0 0.8456517556876256 5 Q06124 1 +Allergic rhinitis 0.4907473309608458 0.7406712462163489 0.4588927976827386 1.0 0.8468130721104377 2 O95394 1 +Agenesis of corpus callosum 0.3978047332118731 0.740475717273147 0.4590113900966939 1.0 0.8468130721104377 70 P00403,Q9BVA1,P61978,O43175,Q969G3,P03886,P23786,Q86XL3,Q15392,Q7LGA3 10 +Molar tooth sign on mri 0.4952552541628522 0.7398341333955645 0.4594006448066154 1.0 0.8470289833139049 4 O43924 1 +Kyphosis 0.3027843204320272 0.7383502305115565 0.4603016499431833 1.0 0.848151895459496 128 Q9Y4R8,P50402,O96028,P01889,Q9Y487,Q96AY3,Q15042,P54886,O95831,P40818,Q7LGA3,P51648,Q06124,P08236,P42858,Q9Y4P3,Q9Y263,Q8TD16,P51812,O75844,Q9BQP7,Q02750,Q9BT22,Q8TB36,Q9UJX6,O75648,Q32P28,Q9Y375 28 +Postaxial foot polydactyly 0.500888319514518 0.7376633294356364 0.460719061182947 1.0 0.8484469304698421 7 Q7Z4L5,O43924 2 +Dilated cardiomyopathy 0.5105505984775658 0.7374466240481696 0.4608507911000892 1.0 0.8484469304698421 32 P00403,Q9BQP7,P42166,O75306,O43819,P03886,P23786,P42167 8 +Thoracic scoliosis 0.5066042146435901 0.7363923180528736 0.4614919783128512 1.0 0.8484469304698421 11 O75844 1 +Focal emotional seizure 0.5052275315055665 0.7362240799493033 0.4615943401566507 1.0 0.8484469304698421 10 Q7L7X3,O43175 2 +Abnormal circulating aspartate family amino acid concentration 0.5022117178133705 0.7361344522619314 0.4616488778985754 1.0 0.8484469304698421 8 P55263,Q9H3L0,Q9UJS0 3 +Abnormal circulating sulfur amino acid concentration 0.5022117178133705 0.7361344522619314 0.4616488778985754 1.0 0.8484469304698421 8 P55263,Q9H3L0,Q9UJS0 3 +Elevated hepatic transaminase 0.3164658423218395 0.7359197695314545 0.4617795252812342 1.0 0.8484469304698421 84 O75880,Q15067,O43772,Q9Y3Z3,Q9Y285,Q8N511,Q9UJS0,O75648,P23786,Q9Y619,P40855,P55263,P01889 13 +Elbow flexion contracture 0.5139649134674131 0.7341876510314368 0.4628343787205664 1.0 0.8496922789790602 22 Q96AY3,P50402,P23786,P37268,P16435,Q7LGA3 6 +Muscle fiber atrophy 0.5124719018095593 0.7335768679396326 0.4632066634434832 1.0 0.8500294919135909 18 P50402,P61978,P35637,P23786,Q99720 5 +Aplasia hypoplasia involving bones of the lower limbs 0.3226051857074002 0.7320022298272133 0.4641672067733848 1.0 0.8509179650737982 83 Q96AY3,Q03164,O00116,P15260,Q08J23,P42858,O75648,Q7Z4L5,O95831,Q96HY6,Q9Y619 11 +Abnormality of hindbrain morphology 0.2915789561976193 0.7316980350368943 0.4643528960259133 1.0 0.8509179650737982 236 P13073,P12235,Q9UM00,Q15233,O43924,O96028,P49589,P46977,P23786,Q96BR5,Q5JTZ9,Q9Y487,Q9NXN4,Q8N2K0,Q69YN2,Q9Y4W6,O00429,Q53EZ4,Q15042,P54886,P42356,Q969G3,Q8NFH4,P00374,O60216,O60313,O43292,Q15813,P07437,Q9BVA1,Q9HC21,P42858,Q9Y4P3,Q9Y263,O14936,O75312,Q9Y6X9,Q8NHS3,Q99720,P51812,Q8NCW5,Q8TD16,P55795,Q9BQP7,Q9NVI7,O43175,Q9BT22,Q13217,P35637,Q9UJX6,Q5JRX3,Q96B26,O75648,Q96CU9,Q9BUK6,Q6DKK2,P16435,Q9Y320 58 +Abnormality of skeletal maturation 0.3093955542776948 0.7299383301406324 0.4654278814490926 1.0 0.852024151783534 85 Q03164,P13073,Q06124,Q08J23,P54886,Q15800,Q969G3,Q9Y4P3,O96028,O75179,O95831,P48449,Q9Y619,Q9BUK6,Q96J02,P51812,P16435,P51809 18 +Abnormality of tibia morphology 0.5061680606367864 0.728475210942132 0.4663227378160783 1.0 0.85331570415634 12 Q32P28,O95831 2 +Dicarboxylic aciduria 0.5118336154141504 0.7259131943015065 0.4678919873684202 1.0 0.8547990219170936 20 Q9H3L0,O43772,P48735,P23786,Q92947 5 +Abnormal pyramidal sign 0.3046379568276588 0.7244783196970522 0.4687721325777134 1.0 0.8557132448472071 109 Q9NZJ7,P48643,P49327,P49589,Q9Y619,P01889,Q9Y4W6,P54886,O95831,Q9NZ08,O60313,P51648,Q9Y3Z3,P42858,Q9Y263,Q99720,P51812,Q15067,O75306,Q13217,P35637,Q6DKK2 22 +Abnormal retinal morphology 0.2976936602349737 0.7186570951378224 0.4723522250750984 1.0 0.8590706044259783 191 Q9Y4R8,Q9NZJ7,Q9UKG1,O43819,O43924,P36404,O96028,P49327,P03886,P21964,O76024,Q6P4Q7,Q9Y619,P01889,Q92947,Q9Y487,P00403,Q8N2K0,P53992,Q15042,Q9Y287,Q9BW83,Q13432,Q9P0J0,P68371,Q7Z4L5,P38435,Q9NZ08,O60313,Q7LGA3,P07437,Q7KZN9,P11802,P51648,P04439,P42858,Q9Y4P3,O14936,O75312,Q9Y6X9,P40855,Q8NHS3,P51812,Q15067,O75306,O75648,Q96CU9,Q9BUK6,Q92889,Q9Y375,Q9UM00 51 +Memory impairment 0.5010399904084781 0.7174297034411042 0.473108997121372 1.0 0.8597992943653321 37 P00403,Q9NZJ7,Q9Y4W6,P42858,Q9UJS0,Q969G3,P49327,P03886,Q9NZ08,P01889 10 +Abnormal external genitalia 0.2881945273236343 0.7155751326617488 0.4742537330765419 1.0 0.8602748755740084 253 Q06136,Q08J23,O43924,O96028,P49327,O76024,P21964,P46977,P49589,Q9Y619,Q86XL3,P01889,Q15392,Q9Y487,P53992,P61978,Q15042,P54886,P31939,Q969G3,Q9BW83,Q13423,Q9NZ08,Q9UBX3,Q7LGA3,Q6PGP7,P07437,Q06124,Q9Y3Z3,P42858,Q9Y4P3,O14936,P51114,P48449,P40855,O75844,P51809,Q02750,Q9NVI7,O43175,O95470,P38159,O75648,Q96PU5,P37268,P16435 46 +Hyperconvex fingernails 0.49209186474873 0.7153322712335424 0.4744037521845539 1.0 0.8602748755740084 5 P51812 1 +Failure to thrive 0.2879127702950415 0.7151506816431932 0.4745159397996417 1.0 0.8602748755740084 255 O75880,Q03164,P13073,P12235,O43676,Q9NZJ7,O43819,O43924,O96028,P03886,P21964,P46977,P49589,Q9Y619,Q5JTZ9,Q15392,Q92947,Q9Y487,O15228,P00403,P53992,Q5JPH6,Q15042,P54886,Q9P0J0,P40818,Q13423,Q8N5M9,Q7KZN9,Q06124,Q9Y4P3,O96000,Q9Y263,O14936,P40855,P55263,Q9UJS0,Q9Y6M9,O75844,P55795,Q02750,Q9H3L0,Q15067,O00116,O43175,O75306,Q15800,Q00325,Q3ZCQ8,Q96CU9,Q96J02,P37268 52 +Posterior embryotoxon 0.5043372015833276 0.7143472383855625 0.4750124887949281 1.0 0.8605807640474776 13 Q7LGA3,P21964,P53992,Q9Y4P3 4 +Ulnar claw 0.4869425891400047 0.7127316597764458 0.4760118215033504 1.0 0.861157849357841 3 P04792 1 +Mildly elevated creatine kinase 0.5094954377948251 0.7126753788814775 0.47604665538864 1.0 0.861157849357841 21 O75648,Q9BPX6 2 +Autoimmune antibody positivity 0.4998638141536037 0.7111691298205222 0.4769794357168651 1.0 0.8619720617424383 10 P15260,Q96J02 2 +Aplasia hypoplasia involving the pelvis 0.5046605854443721 0.7108561985806716 0.4771733512419311 1.0 0.8619720617424383 14 O95831,P15260 2 +Frontotemporal dementia 0.5009549470363494 0.7098509007020423 0.4777966006152967 1.0 0.8620613606777991 11 P31483,P22626,P35637 3 +Abnormal auditory evoked potentials 0.4946310004181428 0.7089263656491686 0.4783701726183 1.0 0.8627508475352855 7 O60313,Q9NZJ7 2 +Femoral bowing 0.4921654995401158 0.705859771476915 0.4802753469755325 1.0 0.8651482769059652 6 Q32P28 1 +Chorea 0.388672392021774 0.7038783583692659 0.4815085299939383 1.0 0.8666768948413258 71 Q9NZJ7,Q96N66,O43819,Q08J23,P42858,Q9NZ01,P35637,Q7L7X3,O14936,P03886,Q99720,Q9BPX6,Q92947 13 +Abnormal renal tubule morphology 0.5070355672405547 0.7020455041754758 0.4826507859990494 1.0 0.8673487076405201 20 P03886,O43819,P23786,Q9Y4P3 4 +Hypermethioninemia 0.4890494874919112 0.7015459300563008 0.4829623815393429 1.0 0.867561360541179 5 P55263,Q9UJS0 2 +Painless fractures due to injury 0.4818505338078254 0.7007854792123648 0.4834369013821527 1.0 0.8678491130533948 2 Q9H4A3 1 +Occipital encephalocele 0.4842557265581324 0.7006720830791143 0.4835076820228698 1.0 0.8678491130533948 3 O43505 1 +Abnormality of the abdominal wall 0.3032693882624756 0.7002967536588843 0.4837419987016322 1.0 0.8679240398679365 102 P07437,P53992,Q06124,O14936,Q32P28,P21964,Q96HY6,O75844,P51812,Q9Y487 10 +Ichthyosis 0.5050105091323884 0.6986653382646655 0.4847612004302917 1.0 0.8690607519249501 30 P50402,P51648,O43175,O95470,Q15800,P48449,P40855 7 +Scrotal hypoplasia 0.5036643008611824 0.6936316692971712 0.4879132278427525 1.0 0.8722142375536488 17 P07437,P16435 2 +Progressive spasticity 0.5010165270414407 0.6934913114859788 0.4880012765218242 1.0 0.8722142375536488 14 P51812,O60313,Q9NZJ7 3 +Intellectual disability progressive 0.497375271293192 0.6931096287552365 0.4882407554879737 1.0 0.8722142375536488 11 Q15067,O95831 2 +Hypoplastic toenails 0.5050676644842824 0.6922880292309348 0.4887564661514438 1.0 0.8722142375536488 20 Q08J23,P23786,Q969G3 3 +Erythema 0.5045846950692109 0.6921510048603524 0.4888425036743991 1.0 0.8722142375536488 19 P51648,Q06136,P03886,P40818,P01889 5 +Congenital posterior urethral valve 0.4819202898900883 0.6902186031544892 0.4900567262128354 1.0 0.87224132337969 3 Q9UJX6 1 +Urethral valve 0.4819202898900883 0.6902186031544892 0.4900567262128354 1.0 0.87224132337969 3 Q9UJX6 1 +Abnormal bone structure 0.2936316878288457 0.6900668844709196 0.490152127129162 1.0 0.87224132337969 150 P12235,Q9NZJ7,O96028,Q9Y619,Q86XL3,P22626,Q15392,Q9Y487,O15228,Q96AY3,P61978,Q15042,P54886,O75718,O95831,Q96HY6,P40818,P38435,O43292,Q15813,O75874,Q9HC21,Q9Y4P3,P40855,O75844,P51809,Q02750,O00116,O43175,Q13126,P48735,Q32P28 32 +Scaling skin 0.49209147015053 0.6895079368223022 0.4905036803538976 1.0 0.87224132337969 8 O75844 1 +Meningioma 0.4920481809768929 0.6893095456747944 0.4906284921553867 1.0 0.87224132337969 8 P21912,Q969G3,O96017 3 +Generalized joint laxity 0.4977361746955157 0.6887420628783263 0.490985601061761 1.0 0.87224132337969 12 Q9Y487 1 +Dysuria 0.4919240262120207 0.6887406057767653 0.4909865181748998 1.0 0.87224132337969 8 P01889 1 +Vertebral compression fracture 0.5008880921475024 0.6881993422580712 0.4913272580798544 1.0 0.8725027392300646 15 Q96AY3,Q32P28,Q96HY6,P40818 4 +Fetal onset 0.4876377942641711 0.68530744645575 0.4931499338502834 1.0 0.874705530052431 6 Q9Y285 1 +Inverted nipples 0.4875082168955394 0.6847207744910567 0.4935201371465147 1.0 0.875017804138215 6 P61978 1 +Pulmonary infiltrates 0.4891898754792302 0.6840876125621804 0.4939198435513352 1.0 0.8750380247192877 7 Q9NZ08,P01889,P15260 3 +Abnormal joint morphology 0.2907998561834141 0.6784572518734642 0.4974818193184727 1.0 0.8792747292817084 229 Q9Y4R8,Q03164,P50402,P50851,Q9NZJ7,O96028,P49327,P49589,P21964,P23786,Q9Y619,Q15041,Q86XL3,P01889,Q15392,Q92947,Q9Y487,P10321,Q96AY3,Q8IZA0,O15269,P53992,Q15042,P54886,O75718,O95831,Q96HY6,P38435,Q9NZ08,Q7LGA3,P08236,Q06124,Q9Y3Z3,P42858,Q9Y4P3,Q96A33,O75312,Q9Y6X9,Q8TD16,O75844,Q02750,O43175,P42892,Q9UJX6,Q9UBS4,Q96PU5,Q96J02,P37268,P16435,Q92889 50 +Panniculitis 0.4873527130743776 0.6757346553881639 0.4992091288779456 1.0 0.8806147395882469 7 Q9Y3Z3,P49327 2 +Abnormal involuntary eye movements 0.2865725118866192 0.6754147317489669 0.4994123084951318 1.0 0.8806147395882469 250 P12235,O43676,Q9NZJ7,Q08J23,O43819,O43924,O96028,P03886,O76024,P49589,P01889,Q5JTZ9,Q15392,Q9NXN4,Q9Y4W6,P54886,Q9BW83,O95831,P40818,O60313,Q7LGA3,O43292,Q7KZN9,Q06124,Q9Y3Z3,P42858,Q9Y4P3,O96000,Q9Y263,O14936,P40855,Q99720,Q9Y6M9,Q02750,Q9H3L0,Q15067,Q9NVI7,O43175,O43772,Q9BT22,O75306,Q9H061,P35637,O75648,Q96CU9,Q6DKK2 46 +Abnormal ureter morphology 0.5020482126015529 0.6741542731832396 0.5002132375910551 1.0 0.8815270150519382 22 Q9UJX6,O14936,O76024,P23786,Q92889,Q7LGA3,O75844 7 +Herpes simplex encephalitis 0.4754448398576438 0.6723066391306487 0.5013885040273163 1.0 0.8823722646149551 2 P42224 1 +Lissencephaly 0.4765306932582003 0.6719999921130609 0.5015837013409175 1.0 0.8823722646149551 46 Q9BVA1,O14936,P23786,Q86XL3,Q15392,Q9Y487 6 +Abnormal protein glycosylation 0.495705237062212 0.6683007297794376 0.5039416475990974 1.0 0.8843492984125498 14 Q8N511,Q9Y487 2 +Spinal rigidity 0.493322193159747 0.6680822957613154 0.5040810622635545 1.0 0.8843492984125498 12 Q9BQP7 1 +Progressive cerebellar ataxia 0.4974781664870826 0.6660291692303284 0.5053924561973875 1.0 0.8859602489621259 32 Q7KZN9,O75306,P42858,P35637,O76024,Q9BUK6,Q9Y619,Q96CU9,Q9Y487 9 +Abnormal upper motor neuron morphology 0.4906754359552738 0.6619500314423701 0.5080032460593089 1.0 0.8888084743747302 11 Q99720,P35637 2 +Hyperactive patellar reflex 0.4858107981538336 0.6608258716080131 0.5087239892062576 1.0 0.8889993678726537 8 P13073,Q15233,P54886,Q15041 4 +Primitive neuroectodermal tumor 0.4951031762722428 0.6606243679659666 0.5088532377518091 1.0 0.8889993678726537 15 P07437,Q06124,Q9UJX6,P21912 4 +Abnormal systemic blood pressure 0.3225865657635089 0.6595731079516329 0.5095278163431638 1.0 0.8897488834787444 82 P00403,P53992,Q9NZJ7,O43772,Q9Y4P3,Q9BW83,P03886,P21964,P40818,Q96J02,Q13423,P35611,P01889,P16435,O75844 15 +Esophageal carcinoma 0.4718861209964338 0.6565797430860423 0.5114511775278778 1.0 0.8920706103398396 2 P42224 1 +Posterior pituitary dysgenesis 0.4764094241706275 0.6550777233128982 0.5124177138962867 1.0 0.8927842136478292 4 Q9UHX1,P42356 2 +Infectious encephalitis 0.4841945132545695 0.6534792211293367 0.5134473809306614 1.0 0.8934777397121587 8 Q9NZ08,P01889 2 +Unilateral renal agenesis 0.4966129088028702 0.6531114036165165 0.5136844610612261 1.0 0.8935452975696434 19 Q06124,O75179,Q86XL3,P16435,Q7LGA3 5 +Wide anterior fontanel 0.4957559908698931 0.6519493307297105 0.5144338598992046 1.0 0.8940738714819167 18 Q08J23,O75718,Q32P28,P16435,Q9Y487 5 +Localized skin lesion 0.2938683908933155 0.651246372364844 0.5148874602022728 1.0 0.8940738714819167 189 Q03164,Q9NZJ7,Q06136,Q08J23,O96028,P48643,P49327,P21964,P36551,Q9Y619,P01889,Q15392,Q96AY3,Q8IZA0,O15269,P53992,P61978,P54886,P40818,P38435,Q9NZ08,Q7LGA3,Q6PGP7,P16615,Q06124,O75874,P42858,Q9Y4P3,O75844,Q02750,P35637,Q13126,P48735,O75648,Q96PU5 35 +Abnormal intraocular pressure 0.4753272070538721 0.6502668931629495 0.5155198383375474 1.0 0.8941154894030714 4 P04439 1 +Abnormality of the amniotic fluid 0.3509311951846704 0.6487857605792657 0.5164768625612006 1.0 0.8943677035291945 77 Q70HW3,P53992,O43175,Q9BT22,Q9Y285,P51114,P21964,P23786,O75844 9 +Pseudoepiphyses 0.4771722236505559 0.6481755032396869 0.51687144410073 1.0 0.8943677035291945 5 P51812,O95202,O96028 3 +Pseudoepiphyses of hand bones 0.4771722236505559 0.6481755032396869 0.51687144410073 1.0 0.8943677035291945 5 P51812,O95202,O96028 3 +Abnormality of bladder morphology 0.4821336569422702 0.6441332818318024 0.5194890101458727 1.0 0.8943677035291945 8 P16435 1 +Congenital craniofacial dysostosis 0.4690391459074778 0.6440499243307964 0.519543060724521 1.0 0.8943677035291945 2 Q6NUK1 1 +Long hallux 0.4690391459074759 0.6440499243307876 0.5195430607245268 1.0 0.8943677035291945 2 O60762 1 +Mild postnatal growth retardation 0.4690391459074687 0.6440499243307581 0.5195430607245459 1.0 0.8943677035291945 2 Q9Y3E5 1 +Abnormal thyroid stimulating hormone level 0.4690391459074676 0.6440499243307534 0.519543060724549 1.0 0.8943677035291945 2 O14654 1 +Abnormal urine hormone level 0.4690391459074611 0.6440499243307239 0.5195430607245681 1.0 0.8943677035291945 2 P04637 1 +Increased urinary cortisol level 0.4690391459074611 0.6440499243307239 0.5195430607245681 1.0 0.8943677035291945 2 P04637 1 +Incomitant strabismus 0.4916036480863006 0.6440319074679416 0.5195547435802084 1.0 0.8943677035291945 15 O60313,P42858,O75648 3 +Ankle clonus 0.4858849320323153 0.6398202571528463 0.5222894613402946 1.0 0.8951976114890193 11 P42858,Q9NZJ7 2 +Abnormality of the intrinsic pathway 0.4858544725836919 0.6396799722999921 0.5223806785480631 1.0 0.8951976114890193 11 Q02750,Q06124,Q9Y487 3 +Hypoplasia of the corpus callosum 0.2918484817997679 0.6393363064041152 0.5226041744921894 1.0 0.8952370876258665 161 Q9UM00,Q9NZJ7,Q01105,Q08J23,O43924,Q7L7X3,P03886,P49589,P00403,Q5JPH6,P61978,Q15042,Q9NZ01,Q969G3,O95831,Q9UBX3,Q7LGA3,Q15813,P07437,Q9BVA1,Q96N66,Q9Y3Z3,Q9Y263,O14936,P48449,Q8TD16,O43175,Q9UJX6,Q96B26,Q96PU5,P37268,Q9Y320 32 +Abnormal morphology of the musculature of the neck 0.4857141447239182 0.6390337452068765 0.5228009795054982 1.0 0.8952370876258665 11 Q99720,P35637 2 +Polyphagia 0.4790613770750659 0.6382651540943578 0.5233010910626641 1.0 0.895516712290583 7 Q4J6C6,P42858 2 +Abnormality of the phalanges of the toes 0.4893100094344452 0.6381720886455357 0.5233616641165733 1.0 0.895516712290583 14 O14936,Q7LGA3,O75844 3 +Blepharophimosis 0.4751755172384605 0.6367015252360286 0.5243192798944201 1.0 0.8964745806085551 44 P07437,Q03164,Q08J23,P42858,Q9Y4P3,O75648,Q9Y619,Q7LGA3,O75844 9 +Aplasia hypoplasia involving bones of the thorax 0.4937692430162709 0.6338786938507717 0.5261599912556374 1.0 0.8979822391648649 28 Q03164,Q06124,Q7Z4L5,Q96HY6,Q9Y619,O75844 6 +Adrenocortical carcinoma 0.4692061231755055 0.6338215778538846 0.5261972694995358 1.0 0.8979822391648649 3 P04637,O96017 2 +Prominent superficial blood vessels 0.4840635772894465 0.6314414692933276 0.5277519083743245 1.0 0.8987391395043071 11 Q9Y487 1 +Shawl scrotum 0.47338234225728 0.6313109116852625 0.5278372536649436 1.0 0.8987391395043071 5 Q9Y619,Q9UM00 2 +Decreased fertility in males 0.4804898956224304 0.6290904707946056 0.529289828664842 1.0 0.9008720762056054 9 Q02750,Q06124,P51809 3 +Congenital hepatic fibrosis 0.464056939501774 0.622239220654145 0.5337845799971892 1.0 0.9058711705083612 2 Q10713 1 +Short palpebral fissure 0.4906493147534551 0.6221627067484556 0.5338348854826287 1.0 0.9058711705083612 30 P07437,Q03164,Q9Y619,O75844 4 +Foot dorsiflexor weakness 0.4905732703249278 0.6217608919047803 0.5340991054056119 1.0 0.9059784223045138 30 Q99720,O15269,Q8TB36,O43819,P54886,Q9Y6X9,Q96BR5,P05023,P04792,P46976,Q15813 11 +Limb muscle weakness 0.3693955063246053 0.6204890386657431 0.5349358683868379 1.0 0.9064780035286476 73 P50402,P12235,O15269,Q15067,Q9Y4W6,Q8TB36,O43819,P54886,Q969G3,Q13126,Q15120,Q16637,Q96BR5,P36551,Q99720,P04792,P46976,Q15813 18 +Obstructive sleep apnea 0.47942779326642 0.6170443293488854 0.5372054868971814 1.0 0.9081541912615004 10 P51114,Q15233,Q96A33 3 +Peripheral demyelination 0.4856870805531983 0.6161435762529363 0.5377997640286099 1.0 0.9081541912615004 15 P03886,Q92947,Q9NZJ7 3 +Gonadal neoplasm 0.490150653159225 0.6149749307172061 0.5385712764022945 1.0 0.908844062858406 22 O75874,Q01844,Q9UJX6,P48735,Q13423,P51809 6 +Progressive 0.2944458540474175 0.6132135609952689 0.5397351391789744 1.0 0.9100584632546344 89 P12235,Q5JTZ9,Q9Y4W6,P54886,O95831,O60313,Q15813,Q9NR28,Q16637,P55263,Q8N1F7,Q99720,Q6IA86,P54802,Q9Y6M9,Q9BQP7,Q02750,O95470,Q9UBS4,Q13126 20 +Esophageal varix 0.4642221431114278 0.6119729407774013 0.5405556606439434 1.0 0.9109032838298315 3 P04062,Q9NSD9 2 +Abnormal bleeding 0.2946392141438254 0.6118448689143985 0.5406404003205678 1.0 0.9109032838298315 90 Q02750,P53992,Q06124,Q9UJS0,Q969G3,Q9UGP8,Q13126,O76024,P21964,P23786,Q4KMQ2,P40818,Q9Y487,Q9NZ08,P01889,Q92947,O75844 17 +Tremor 0.2886722045926438 0.6102268827781543 0.5417115241534252 1.0 0.9112987162893664 149 Q9NZJ7,O43924,P03886,O76024,Q96BR5,Q5JTZ9,Q92947,Q9Y287,O95831,Q9BPX6,O60313,O43292,Q9Y3Z3,P42858,Q9Y4P3,O14936,Q16637,Q99720,Q9UJS0,P04080,P35637,Q5JRX3,Q15120,Q9BUK6,Q6DKK2,Q6P4A7 26 +Cerebellar cortical atrophy 0.4632120256686497 0.6075641410359649 0.543476589849655 1.0 0.9116596212533138 3 Q9Y263 1 +Focal non motor seizure 0.4786287888950269 0.6065610170518803 0.5441422774733433 1.0 0.9120899269376376 11 Q7L7X3,Q01105,O43175 3 +Myopia 0.2992945493906695 0.60648653853122 0.5441917186627889 1.0 0.9120899269376376 85 Q13555,Q02750,Q15067,P51648,Q06124,P61978,Q9NVI7,Q08J23,P42858,O43819,Q969G3,Q9Y4P3,O14936,Q9Y487,O43292 15 +Impaired visuospatial constructive cognition 0.4752572520912056 0.6054407120628768 0.5448862070156679 1.0 0.912598340772804 9 P03886,P42858 2 +Fatigable weakness of swallowing muscles 0.4820546057917214 0.6042858219214338 0.5456536309214872 1.0 0.9135441733146892 14 Q15165,P35637,P50995,Q92804 4 +Abnormal thoracic spine morphology 0.4872124125459441 0.5982110448487159 0.5496991226957735 1.0 0.9192927443376072 24 O95831,O75844,P51648 3 +Autistic behavior 0.2898880177254908 0.5971507354097028 0.5504067471082874 1.0 0.9197971281755604 168 O43676,Q08J23,Q7L7X3,P03886,P21964,O76024,P53992,Q9NZ01,Q969G3,O75179,Q7LGA3,Q96N66,P42858,Q9Y4P3,O96000,O14936,P48449,P51812,Q9Y6M9,P55795,Q15067,O75648,Q96CU9,Q9BUK6 24 +Abnormality of fontanelles 0.4784759666963085 0.5966037489513715 0.5507719676752354 1.0 0.9197971281755604 38 Q9BT22,Q08J23,P54886,O75718,Q32P28,Q9Y619,Q9Y487,P40855,O75844,P51812,P16435,O15228 12 +Cardiac conduction abnormality 0.4863405340006762 0.5953701282722509 0.5515960885047089 1.0 0.9206865745468956 28 P00403,P50402,Q06124,O43772,O43819,P03886,P23786,P46976 8 +Muscle stiffness 0.4851608945904755 0.5947878553169639 0.5519852866045643 1.0 0.9206865745468956 20 Q9Y3Z3,Q15392,P23786,Q9NZJ7 4 +Abnormal circulating progesterone level 0.467190572367707 0.5939054283395077 0.5525753681272139 1.0 0.9206865745468956 6 P16435 1 +Decreased circulating progesterone 0.467190572367707 0.5939054283395077 0.5525753681272139 1.0 0.9206865745468956 6 P16435 1 +Abnormal choroid plexus morphology 0.4669571856998112 0.5928771505006969 0.5532633707763035 1.0 0.9209496870849188 6 O43175 1 +Abnormality of retinal pigmentation 0.4115195203562473 0.592753255263464 0.5533462952354027 1.0 0.9209496870849188 63 P00403,Q7KZN9,Q15067,P51648,O75306,Q15042,Q9BW83,Q13432,O76024,P03886,Q7Z4L5,Q9BUK6,P40855,Q96CU9,Q8NHS3,P51812 16 +Abnormal conjugate eye movement 0.2758427711984578 0.5916490047500432 0.5540856513119845 1.0 0.9218398045268048 273 Q03164,P12235,O43676,Q9NZJ7,Q08J23,O43819,O43924,O96028,P03886,P21964,Q9Y619,Q15392,Q9Y487,P53992,Q969G3,O75179,O60313,Q7LGA3,Q7KZN9,Q9BVA1,Q06124,P42858,Q9Y4P3,O96000,O14936,P40855,Q99720,P51812,Q9Y6M9,P55795,Q02750,Q15067,Q9NVI7,O43175,Q9BT22,O95470,O75306,Q9H061,P35637,O75648,Q96PU5,Q96CU9,P16435 43 +Noncompaction cardiomyopathy 0.458949236799493 0.5890336046931788 0.5558387310734287 1.0 0.9237334664262328 3 Q15233 1 +Long fingers 0.3804543144883986 0.587472483475558 0.5568864255897581 1.0 0.9244519779495542 70 Q03164,P07437,P53992,Q9Y285,Q06136,Q969G3,P21964,P23786,P51812,P16435,P55795 11 +Lower limb spasticity 0.3849125684661355 0.5857361462636058 0.5580528396046853 1.0 0.9260471826577013 69 Q7KZN9,Q6DKK2,Q9Y4W6,Q9NZJ7,Q9Y3Z3,O75306,P54886,P35637,P48643,Q9P0J0,O95831,Q9Y619,Q15041,P40818,Q99720,Q96CU9,O60313 17 +Large fleshy ears 0.4555160142348641 0.5852203738163876 0.5583995472548238 1.0 0.9262814720196876 2 P21281 1 +Elevated pulmonary artery pressure 0.4833702111511971 0.5836573731007254 0.5594508516678176 1.0 0.9273427688366508 21 O75844,P03886,O96000,P01889 4 +Hypoglycemic coma 0.4699151392450401 0.5814810830433099 0.56091626403592 1.0 0.928068887791369 9 Q13423 1 +Abnormality of temperature regulation 0.2927929735572739 0.5812940718342336 0.5610422753182738 1.0 0.928068887791369 92 P00403,Q02750,P47985,P15260,Q9NZJ7,O43772,Q9Y3Z3,P61978,Q9HC21,Q8N1F7,Q14C86,O14936,P03886,P23786,Q8NFH4,Q9NZ08,P01889 17 +Narrow palate 0.4812469650565286 0.578730099145332 0.5627713032184698 1.0 0.9297691582132124 32 Q06124,P61978,Q9NZ01,P23786,Q9Y619,P51812,P16435 7 +Fatigable weakness of respiratory muscles 0.4772999727411867 0.5769951561778366 0.5639427276799212 1.0 0.9306848222628844 15 Q15165,P35637,P50995,Q92804 4 +Thyroiditis 0.4631338841259373 0.5760856575782055 0.5645572852816734 1.0 0.9313542037937416 6 P49327,P50851,Q96J02 3 +Cyanosis 0.4803012543014173 0.5744060149535273 0.5656930835570217 1.0 0.9320317862320344 19 O43772,Q9Y3Z3,P51812,O75844 4 +Hypersplenism 0.4627174335627347 0.5742628724976903 0.5657899292530411 1.0 0.9320317862320344 6 Q96J02,Q9NZJ7 2 +Fatigable weakness of bulbar muscles 0.4767090353293162 0.574255082185812 0.565795200162158 1.0 0.9320317862320344 15 Q15165,P35637,P50995,Q92804 4 +Photophobia 0.4761753437143097 0.5702408787332461 0.568514333639571 1.0 0.9349092596718932 36 P51648,P04439,Q9Y4W6,Q9NZJ7,P04080,Q9Y287,Q8WWV3,Q13432,P49327,P48449,Q9NZ08,P01889,Q92889 13 +Prenatal maternal abnormality 0.4687013664577219 0.5686517874270107 0.5695924725897776 1.0 0.9349092596718932 10 O43772 1 +Recurrent paroxysmal headache 0.470234446934569 0.5685152070396082 0.569685182781551 1.0 0.9349092596718932 11 P03886 1 +Angiofibromas 0.4566312634950328 0.5683110589105917 0.5698237710935634 1.0 0.9349092596718932 4 P21912 1 +Adenoma sebaceum 0.4566312634950328 0.5683110589105917 0.5698237710935634 1.0 0.9349092596718932 4 P21912 1 +Visual field defect 0.4688786634315099 0.5667985941406128 0.5708510258512636 1.0 0.9362538477116612 41 P00403,Q9BVA1,Q9H061,Q9Y287,Q969G3,P03886,P40855,Q8NHS3,P01889,O60313 10 +Hyperventilation 0.4607041266873034 0.5654684034360576 0.5717552096219183 1.0 0.9373956819810788 6 P47985,P03886 2 +Cone shaped epiphysis 0.4672785772222798 0.5622933028127944 0.5739162005441969 1.0 0.9386573705682666 10 O95831 1 +Inappropriate crying 0.4619230982571468 0.5621629064217674 0.5740050316961709 1.0 0.9386573705682666 7 O43175 1 +Abnormal clavicle morphology 0.4760592516361764 0.561890103958376 0.5741908965291127 1.0 0.9386573705682666 17 Q96AY3,O75844,Q9Y619 3 +Female infertility 0.4498220640569408 0.5608237117696099 0.5749177204654679 1.0 0.9388256384526766 2 Q15645 1 +Hemiplegia hemiparesis 0.4778266723323517 0.560567884166403 0.5750921502969999 1.0 0.9388256384526766 32 P00403,Q9BVA1,Q9Y3Z3,Q969G3,P03886,P01889,O60313 7 +Stillbirth 0.4698614252353047 0.5602112593586738 0.5753353479934087 1.0 0.9388256384526766 12 O75844,O43175 2 +Nasal speech 0.4791105290621122 0.5596700354201877 0.5757045245498065 1.0 0.9390880536177988 29 Q9BQP7,P53992,P42858,O75648,P21964,Q9Y487 6 +Ectrodactyly 0.4734754728456444 0.5593065187111775 0.5759525472662217 1.0 0.9391527245039296 15 Q8TB36,O96028,P48449,Q99720,P04792 5 +Abnormal cardiac ventricular function 0.4742021342094636 0.5577262117431464 0.5770313560154259 1.0 0.940220610938776 16 P00403,P03886,O75844 3 +Narrow nasal ridge 0.4607721309709071 0.5571251844518751 0.5774419017258781 1.0 0.940220610938776 7 P54886,O75844 2 +Limited elbow movement 0.4781022954967568 0.5564062709837956 0.5779331529204197 1.0 0.9403340212577974 30 Q96AY3,P50402,Q06124,P23786,Q96J02,P37268,P16435,Q7LGA3 8 +Curly hair 0.465832678686442 0.5558469172347315 0.5783155090083711 1.0 0.9403340212577974 10 Q02750,P55795,Q96A33 3 +Variable expressivity 0.3945605223311644 0.5558021616783504 0.5783461075941012 1.0 0.9403340212577974 66 P00403,Q9BVA1,Q70HW3,Q9NZJ7,Q9Y3Z3,O95470,Q9BUF5,Q9H061,P03886,Q6P4A7,P46976 11 +Abnormal circulating albumin concentration 0.4778456299225646 0.5518080497813185 0.5810798715275785 1.0 0.9440982381729728 28 Q5XKP0,Q14C86,P15260,Q9BW27,Q9BT22,Q9Y285,O95470,Q9NSD9,Q8NFH4,Q12769,Q8N1F7,Q9UJS0,Q6PGP7 13 +Abnormal dentin morphology 0.4552253103985689 0.551807553794098 0.5810802113804807 1.0 0.9440982381729728 5 Q96AY3 1 +Aplasia hypoplasia of the clavicles 0.4645173378926935 0.5499963117609226 0.5823219032971134 1.0 0.9457747092468792 10 O75844 1 +Constitutional symptom 0.2874701246630465 0.5495093369393289 0.5826559587404541 1.0 0.9459763710530356 213 P50402,P12235,Q70HW3,Q07021,Q9NZJ7,Q14C86,P49327,P21964,P23786,P36551,P01889,P22626,Q92804,O15269,P53992,P54886,Q969G3,Q8NFH4,Q96HY6,P40818,Q13423,Q9NZ08,O60313,Q14566,Q06124,P15260,O75874,Q9Y4P3,Q9UGP8,O14936,Q9Y6X9,Q99720,P51812,Q8N1F7,Q9UJS0,O75844,Q9H3L0,Q12769,P42892,P23378,P35637,Q15800,Q9UBS4,Q3ZCQ8,P48735,Q53H12,Q15165,Q9BUK6,Q92889 49 +Abnormal basal ganglia mri signal intensity 0.4770893913748872 0.5480247779167856 0.5836748894109887 1.0 0.9466076741904734 24 Q7KZN9,O75306,P03886,Q96CU9,Q9BPX6,Q92947 6 +Cerebellar cyst 0.4753353444998665 0.5473961227804336 0.5841066184213441 1.0 0.9469670968435244 32 P07437,P23786,Q9Y487,O43175 4 +Male reproductive system neoplasm 0.4652803040656882 0.5462987791457588 0.5848605753220992 1.0 0.9475077688629407 11 Q13423,Q01844,P51809 3 +Laryngomalacia 0.4675504904698198 0.5435073818693553 0.5867805097280718 1.0 0.9499352576668174 13 P21964,P53992,P16435 3 +Abnormal elasticity of skin 0.4412791723126409 0.5427369289784475 0.5873109441336599 1.0 0.9501913247881826 52 Q02750,P07437,Q06124,O43175,P54886,Q9Y4P3,O96000,Q13126,P40818,O75844,P51812,Q9Y487 12 +Positional foot deformity 0.3180196615848004 0.5423696320655501 0.5875638954792273 1.0 0.9501913247881826 81 O96028,P21964,Q9Y619,Q15392,Q9Y487,Q96AY3,P53992,P61978,Q53EZ4,P54886,P42356,P40818,P04792,O60216,P08236,Q9HC21,Q9UHX1,Q96A33,Q8TD16,Q9NVI7,Q8TB36,Q9UJX6,P16435,Q9UM00 24 +Limb girdle muscle weakness 0.4756355396902878 0.5422152964303727 0.5876701989322242 1.0 0.9501913247881826 23 P12235,Q9NZJ7,O14979,Q13126,Q9Y6X9,O60313,P46976 7 +Abnormality of the shoulder girdle musculature 0.4756827734355034 0.5420530125530827 0.5877819865785341 1.0 0.9501913247881826 29 P50402,Q06124,O14979,O60313,P46976,Q9Y487 6 +Head tremor 0.4639834864588923 0.5405142674593814 0.588842424332328 1.0 0.9512232281239436 11 Q99720,P35637 2 +Neoplasm of fatty tissue 0.4583087276972578 0.5380734385903974 0.5905263490719479 1.0 0.9532405505596588 8 Q15437,O95140,Q9BUK6,P21912 4 +Abnormality of peripheral nerves 0.4593673924536982 0.5307247291038628 0.5956095469502984 1.0 0.9595724900289584 43 O15269,Q8N2K0,Q9NZJ7,Q8TB36,Q9Y3E5,P48643,Q9H4A3,Q15120,O95140,O95831,Q9Y6X9,Q9Y619,P43243,Q99720,P04792,Q92889 16 +Craniofacial hyperostosis 0.4526455850192108 0.5305737588294136 0.5957141839585147 1.0 0.9595724900289584 6 P51812 1 +Multiple renal cysts 0.4659152865216621 0.5301999481401499 0.5959733070036997 1.0 0.9596469077047785 14 P21964,P53992,Q9Y4P3 3 +Abnormal nerve conduction velocity 0.4652505263849275 0.5293947385264522 0.5965316473123572 1.0 0.9602029051559978 39 O15269,Q9NZJ7,Q8TB36,Q15120,O95831,Q9Y619,Q99720,P04792 8 +Seborrheic dermatitis 0.4543057441237689 0.5290117975294352 0.5967972659311542 1.0 0.9602874964483086 7 P21964 1 +Headache 0.3950620394699626 0.5266400633121349 0.5984435650273436 1.0 0.962566222342082 65 P00403,P12235,Q14C86,Q8N1F7,Q9Y3Z3,Q969G3,P03886,P23786,Q8NFH4,P40818,Q9NZ08,P01889,O60313,Q92947 14 +Coxa valga 0.4693353834858951 0.5263564244328955 0.5986405860272588 1.0 0.962566222342082 18 Q9Y619,O75844,Q96A33 3 +Emg chronic denervation signs 0.4634400258921883 0.5249905129057093 0.5995897860642203 1.0 0.9633950596216652 13 Q9NZJ7,O43819,P22626,P04792,O60313 5 +Dermal atrophy 0.4723121858309094 0.5236379114822037 0.6005304076263847 1.0 0.9633950596216652 25 Q15392,O75844 2 +Microdontia 0.472260877185499 0.5233854713254856 0.6007060325521569 1.0 0.9633950596216652 25 Q96A33,Q7LGA3,Q9Y619,Q9Y487 4 +Abnormality of the intrahepatic bile duct 0.443574225703102 0.523297274872593 0.6007673971015086 1.0 0.9633950596216652 3 Q10713,P02545 2 +Type i diabetes mellitus 0.4600935761802165 0.523243509830954 0.6008048066570602 1.0 0.9633950596216652 11 P00403,P50851,Q13217,P03886,Q96J02 5 +Focal t2 hyperintense basal ganglia lesion 0.4686128140538201 0.5229939982197426 0.6009784298654366 1.0 0.9633950596216652 18 O75306,Q7KZN9,P03886,Q96CU9 4 +Tetraplegia tetraparesis 0.4596560012088911 0.5226004996942694 0.6012522927285608 1.0 0.9633950596216652 42 Q5JPH6,Q9NZJ7,Q8NCW5,P54886,P35637,O95831,Q13423,Q9UBX3,Q15813 9 +Fibrous tissue neoplasm 0.4684794075628142 0.5223736746000742 0.6014101816059634 1.0 0.9633950596216652 18 Q13126,Q15392,Q969G3 3 +Abnormal endocardium morphology 0.4628080440077368 0.5221557139453952 0.6015619177326885 1.0 0.9633950596216652 13 Q9NZ08,P01889,Q9Y4P3,Q06124 4 +Generalized muscle weakness 0.4710119813463506 0.5219270536595871 0.6017211211082734 1.0 0.9633950596216652 31 P12235,P50995,P42858,P35637,P21912,O95831,Q9Y6X9,Q15165,Q5JTZ9,Q92804 10 +Epidermal acanthosis 0.4521534042868609 0.5197285350953432 0.6032527954201299 1.0 0.964819144413955 7 Q06136 1 +Soft tissue sarcoma 0.4713864898635417 0.5190636075632784 0.6037163854265795 1.0 0.9652138243726548 28 Q02750,Q06124,Q969G3,Q13126,Q15392 5 +Abnormality of pulmonary circulation 0.4713200067080885 0.5187603275445002 0.603927886561102 1.0 0.9652138243726548 25 P00403,O96000,P49327,P03886,Q9NZ08,P01889,O75844 7 +Hypoplasia of the pons 0.4655218147089179 0.5177336179434057 0.6046441392760489 1.0 0.9656254005066326 16 Q9BVA1 1 +Muscle fibrillation 0.4643315845050361 0.5174699259633284 0.604828157450682 1.0 0.9656254005066326 15 P04792,P51114,O95831 3 +Micromelia 0.4694956047035113 0.5169899029411882 0.6051632072963062 1.0 0.9658181923811798 21 O43175,P48735,O75718,Q7Z4L5,Q96HY6,Q15392 6 +Impairment in personality functioning 0.2861613980502494 0.5146972321931838 0.6067646078573952 1.0 0.9671146515219852 188 Q03164,P12235,Q9NZJ7,Q08J23,P03886,P21964,O76024,P49589,P36551,P01889,Q5JTZ9,Q92804,P00403,Q9NXN4,P53992,Q9Y4W6,Q9NZ01,Q969G3,P40818,Q7LGA3,Q7KZN9,P16615,Q96N66,P42858,Q9Y4P3,P51812,P55795,O43175,O75306,P35637,O75648,Q96CU9,Q9BUK6,Q6DKK2 34 +Hypoplasia of teeth 0.4683650224842828 0.5145981386177166 0.6068338660981083 1.0 0.9671146515219852 20 P51648,O75844 2 +Dilated fourth ventricle 0.467524217516146 0.5133403768167206 0.607713244654305 1.0 0.9677092372995552 34 P07437,O43175,O14936,P23786,Q9Y487 5 +Telecanthus 0.4682177108293335 0.513232497666501 0.6077886960576584 1.0 0.9677092372995552 33 Q03164,P53992,Q08J23,P21964,Q86XL3,O75844 6 +Oval face 0.4485665518762033 0.5131088704153849 0.6078751669256004 1.0 0.9677092372995552 6 O14936 1 +Abnormal jejunum morphology 0.4384341637010632 0.5127833884433751 0.6081028509597834 1.0 0.9677092372995552 2 P49454 1 +Choroid plexus carcinoma 0.4407262370950549 0.5113274755093188 0.6091217690305781 1.0 0.9677655507652028 3 P04637,O96017 2 +Anterior open bite malocclusion 0.4380782918149333 0.5112994434897101 0.6091413946403559 1.0 0.9677655507652028 2 P21281 1 +Progressive spastic quadriplegia 0.4501801585288278 0.511251716324086 0.6091748097450367 1.0 0.9677655507652028 7 Q9NZJ7 1 +Diminished movement 0.4658318438814179 0.5100938623572608 0.6099857049261246 1.0 0.9682970930471494 18 P51114,P42858,O95831 3 +Hepatitis 0.4612424044370395 0.5091260887383623 0.6106638462103389 1.0 0.9682970930471494 14 P49327,Q9Y619,Q96J02 3 +Abnormality of the breast 0.2864729039246733 0.5086892917762802 0.6109700294032083 1.0 0.9682970930471494 90 P07437,Q15067,Q06124,P61978,O75874,O96028,Q96A33,P48735,P23786,Q9Y619,P31751,Q7LGA3,P51809 13 +Abnormality of earlobe 0.4686981796957711 0.5086275736485806 0.61101329767608 1.0 0.9682970930471494 23 Q15392,P21964,P53992,P16435 4 +Hypoplasia of the iris 0.444616789378321 0.5064940975870775 0.612509832186682 1.0 0.9698076939336014 5 Q7LGA3,O96028,O95202 3 +Abnormality of the gastric mucosa 0.4605277503819477 0.5059194218682644 0.6129132173758123 1.0 0.9698076939336014 14 P49327,O76024,Q9Y4P3,Q6PGP7 4 +Gout 0.4419515669515699 0.5057354120693166 0.6130424051512826 1.0 0.9698076939336014 4 P00492,Q9UBS4,P61619 3 +Aplasia hypoplasia of the nasal bone 0.4385902456390217 0.5023959974188614 0.6153889940018613 1.0 0.9717614380202252 3 P10644,Q6NUK1 2 +Medulloblastoma 0.4408831908831909 0.5012510537965258 0.6161944478118584 1.0 0.9717614380202252 4 P35222,P04637,O96017 3 +Microglossia 0.4382342470630126 0.5009113176672471 0.6164335370090579 1.0 0.9717614380202252 3 Q9UBM7,Q03252 2 +Aplasia hypoplasia of the tongue 0.4382342470630126 0.5009113176672471 0.6164335370090579 1.0 0.9717614380202252 3 Q9UBM7,Q03252 2 +Abnormality of the 5th toe 0.4493931704156129 0.4994769389749762 0.6174434289020361 1.0 0.9726730283332669 8 Q7Z4L5,O43924 2 +Ventricular arrhythmia 0.4652959772934559 0.4978694604062202 0.6185760538837615 1.0 0.9735295600740652 33 P00403,P50402,P12235,O75306,O43772,P03886,P23786,P46976 8 +Emg myopathic abnormalities 0.4667327104438425 0.4975171174633337 0.6188244349959817 1.0 0.9735295600740652 24 P50402,P12235,P51114,Q9BUK6,P46976 5 +Generalized abnormality of skin 0.2852384851439835 0.497479206566853 0.6188511625498552 1.0 0.9735295600740652 189 Q06136,Q08J23,O15118,P49327,P03886,P21964,P36551,P01889,Q9Y487,P00403,Q8IZA0,O15269,P53992,Q15042,P54886,P40818,P38435,P51648,Q06124,Q9Y3Z3,Q9Y4P3,O14936,Q99829,P40855,P51812,Q9UJS0,O75844,Q02750,O43175,O43772,O75306,P04080,Q00325,Q13126,O75648,P37268 36 +Enlarged thorax 0.4594787170339199 0.4955471943621129 0.6202139168929635 1.0 0.9747194228057184 15 Q02750,Q32P28,Q06124,O75844 4 +Talipes equinovarus 0.4060387943181837 0.4940540878250933 0.6212679813613358 1.0 0.9756212256708988 61 O96028,P21964,Q9Y619,Q15392,Q9Y487,Q96AY3,P53992,P61978,Q53EZ4,P54886,P40818,P04792,P08236,Q9HC21,Q96A33,Q8TD16,Q8TB36,Q9UJX6,P16435,Q9UM00 20 +Abnormality of the nasal bone 0.4387464387464397 0.4923127525991601 0.6224982662986753 1.0 0.9765400926585904 4 P35222,P10644,Q6NUK1 3 +Papilloma 0.4494387603242155 0.4916241778938098 0.622985048093988 1.0 0.9766238649598624 9 P16615,Q92889,P21912 3 +Absent septum pellucidum 0.463918643158219 0.4826492440172751 0.6293448076235548 1.0 0.9831740200899 25 Q15392,Q08J23,Q9NZ01,Q96N66 4 +Episodic pain 0.4538186224591188 0.4822042101171926 0.6296608863531217 1.0 0.9833269628529172 13 P23786 1 +Bowel diverticulosis 0.4451528127676075 0.4813616214522358 0.6302595082247158 1.0 0.9835801951415492 8 Q9Y4P3 1 +Abnormality of complement system 0.4328942684229298 0.4787787738759079 0.6320960186044233 1.0 0.9842238353257764 3 Q03252,P02545 2 +Aplasia hypoplasia of the earlobes 0.4444495723727465 0.4783731681582302 0.6323846275698435 1.0 0.9842238353257764 8 P21964 1 +Rapidly progressive 0.4444289972982648 0.4782858026765234 0.6324467998570591 1.0 0.9842238353257764 8 Q8NHS3,Q8TB36 2 +Abnormality of fundus pigmentation 0.4350020964242791 0.4767500488220917 0.6335401191126357 1.0 0.9842238353257764 4 Q9Y619 1 +Pulmonary artery dilatation 0.4525377804915136 0.4765707430097599 0.6336678210426632 1.0 0.9842238353257764 13 O75648,P42858 2 +Narrow mouth 0.3762243825664244 0.4751965342304609 0.6346468971496 1.0 0.9842238353257764 68 P07437,P53992,Q9NVI7,Q15042,P54886,P42858,P16435,O75648,P21964,Q9Y619,O75844,Q15392,Q7LGA3,Q9Y487 14 +Abnormality of female external genitalia 0.4622140492190193 0.4749499847504355 0.634822622812973 1.0 0.9842238353257764 30 Q08J23,Q15042,P16435,P40855,Q9Y619,Q15392,P51809 7 +Ovarian neoplasm 0.4559462377969631 0.4743554396251344 0.6352464635037078 1.0 0.9842238353257764 16 O75874,Q01844,P51809,P48735 4 +Facial diplegia 0.4471397418744562 0.4740332057830042 0.6354762282666984 1.0 0.9842238353257764 10 P12235,O43819 2 +Fine hair 0.4500353162652137 0.4722133207179636 0.6367745326299883 1.0 0.984574939018644 12 Q02750,P49589,Q08J23,P04080 4 +Acute hepatic failure 0.4481951044074711 0.4712175956129469 0.6374853546670707 1.0 0.9849662301969446 11 P01889,O75648 2 +Aplasia hypoplasia of the nails 0.4158220432316641 0.4689067868719019 0.6391362649292032 1.0 0.986028294441298 57 P16615,Q08J23,Q969G3,O14936,P23786,O75844,P51812,Q9Y487 8 +Germ cell neoplasia 0.4420815847717732 0.4683444157834895 0.639538310559999 1.0 0.986028294441298 8 Q9UJX6,P51809,O96017 3 +Dry skin 0.4610752009681085 0.4681124469988361 0.6397041785991471 1.0 0.986028294441298 29 Q02750,P11802,P51648,Q9Y3Z3,Q06136,Q08J23,P04080,P37268,Q6PGP7 9 +Abnormality of toe 0.2809428678262884 0.4672310021375689 0.6403346152336322 1.0 0.9866626020027284 155 Q03164,P13073,Q08J23,O43924,P21964,P23786,Q96BR5,P53992,P61978,Q969G3,Q7Z4L5,P04792,Q7LGA3,P42858,Q9Y4P3,Q9Y263,Q96A33,O14936,Q99720,P51812,O75844,O43175,Q8TB36,O75648,Q96PU5,Q96J02,P37268 27 +Truncus arteriosus 0.4430843244971226 0.4644663579847732 0.6423136571190433 1.0 0.9892724646255556 9 P21964 1 +Abnormality of cranial sutures 0.3475488043067047 0.4642517550055361 0.6424673849476372 1.0 0.9892724646255556 74 Q96AY3,P53992,P61978,Q08J23,O75718,P21964,O95831,Q32P28,Q9Y619,O75844,P51812,P16435,Q9Y487 13 +Slowly progressive 0.4209872728274904 0.4635257775356381 0.6429875422225126 1.0 0.9893466064572092 55 P50402,P12235,Q96BR5,P05023,Q9NXN4,Q8N2K0,Q69YN2,Q9Y4W6,P31483,P54886,O14979,Q9P0J0,O95831,P04792,Q9Y6X9,Q16637,Q99720,P46976,Q15120 19 +Ventriculomegaly 0.2808605134891849 0.461424359552068 0.6444941780783995 1.0 0.990363198295038 157 Q9NZJ7,Q01105,O43819,Q7L7X3,P23786,Q86XL3,Q15392,Q92947,Q9Y487,Q969G3,P07437,Q9BVA1,Q9Y3Z3,Q9HC21,P42858,Q9Y263,O14936,P51812,O43175,O75306,Q96CU9,Q9Y320 22 +Abnormal midbrain morphology 0.4380886037835574 0.4600639040842529 0.6454703520641099 1.0 0.9911873515342224 7 O43924,Q15813 2 +Contractures of the joints of the lower limbs 0.4332516851584364 0.4587910754912989 0.6463842041496028 1.0 0.9922525913154836 50 Q96AY3,P50402,Q9Y4R8,Q8IZA0,Q9HC21,P37268,Q08J23,Q8TD16,P35637,Q9UJX6,Q92889,P23786,Q86XL3,Q99720,O60313,Q7LGA3 16 +Abnormal glycosylation 0.455390172877573 0.4580729542870915 0.6469000288795503 1.0 0.9925998024575572 19 Q9BT22,Q8N511,Q9Y487 3 +Abnormality of the parathyroid morphology 0.4348502851089552 0.455459634102104 0.6487786014414016 1.0 0.9940290367649808 6 P48735 1 +Abnormality of the upper arm 0.4528015956092662 0.4552418008021737 0.6489352910132913 1.0 0.9940290367649808 17 P50402,O00116,O14979,P16435,O15228 5 +Involuntary movements 0.2721035086387239 0.4539973044360998 0.6498307669315269 1.0 0.9944948273549716 287 Q03164,P13073,P12235,Q9NZJ7,Q01105,Q08J23,O43819,O43924,O96028,Q7L7X3,P48643,P03886,O76024,P49589,Q96BR5,Q9Y619,Q9BWD1,P22626,Q5JTZ9,Q92947,P00403,Q9Y4W6,Q9Y287,P54886,Q9NZ01,Q969G3,Q9P0J0,O95831,P40818,P04792,Q9BPX6,Q9UBX3,O60313,O43292,Q96N66,Q9Y3Z3,P42858,Q9Y4P3,O14936,P51114,Q16637,Q9Y6X9,Q8NCW5,Q99720,Q9UJS0,Q8TD16,Q6IA86,P55795,O14949,O43175,P61457,O75306,P23378,P04080,P35637,Q5JRX3,Q3ZCQ8,Q15120,Q96CU9,Q9BUK6,Q6DKK2,Q6P4A7 62 +Abnormal circulating androgen level 0.4499288464793896 0.4530317291824098 0.6505258942004579 1.0 0.9952207077941152 15 Q13423,P16435,Q969G3 3 +Oligohydramnios 0.4577707560202069 0.4525933490667809 0.6508415888416699 1.0 0.9953658096061778 30 Q07021,Q9Y285,Q53EZ4,Q9UHX1,Q9NSD9,P51114,P23786,P16435,Q92889,Q7LGA3 10 +Motor polyneuropathy 0.4419406833550184 0.4518351384932789 0.6513877537257646 1.0 0.9957538380035128 10 O43819,P36551,Q15041 3 +Limb girdle muscle atrophy 0.4430967423335176 0.4493262671459238 0.6531963119073279 1.0 0.996599789358946 11 O14979,P50402 2 +Aplasia hypoplasia involving the skeletal musculature 0.4393495153494374 0.4486847819492231 0.6536590641328803 1.0 0.996968325565784 9 Q9Y487 1 +Cerebral visual impairment 0.4157297319436709 0.447646029855654 0.6544086777207148 1.0 0.997436560868198 56 P00403,P12235,O43175,Q96N66,Q01105,Q08J23,Q9NZ01,Q96A33,Q7L7X3,P03886,Q96CU9,P37268 12 +Abnormal corneal epithelium morphology 0.4496181239126057 0.4461585100254698 0.6554827506989291 1.0 0.998735888235319 16 Q9NZ08,P01889,P51648,O75844 4 +Limb dystonia 0.4453865889854783 0.445407000042007 0.6560256544172991 1.0 0.9991376053509344 13 Q99720,P35637,Q92947 3 +Abnormal atrioventricular conduction 0.4436077327682423 0.4444447144858745 0.6567210913649664 1.0 0.9991376053509344 12 O43772,Q06124 2 +Early onset of sexual maturation 0.4472964945215453 0.4436464699911547 0.6572982027658134 1.0 0.9991376053509344 41 O75874,P42858,Q9Y4P3,O14936,P48735,O75648,Q13423,Q7LGA3 8 +Woolly hair 0.4292682187967588 0.4426987254044372 0.6579836645058788 1.0 0.9998423384787576 5 Q96A33 1 +Tissue ischemia 0.4495589152265188 0.4407682141642939 0.6593808071077911 1.0 1.0 17 Q9NZ08,P01889,Q9Y4P3,O75844 4 +Focal segmental glomerulosclerosis 0.4530250981046446 0.4400052036351433 0.6599333384899004 1.0 1.0 21 P00403,O95470,P03886,Q8NFH4,Q8N1F7 5 +Lipodystrophy 0.4528269251768778 0.4396649600053627 0.6601797845417776 1.0 1.0 35 P50402,Q9Y3Z3,P42167,P40818,O75844,P31751,Q9Y487 7 +Inappropriate antidiuretic hormone secretion 0.419928825622766 0.4371740763995367 0.6619851086027955 1.0 1.0 2 Q13724 1 +Lactic acidosis 0.3539460765536529 0.4364474707262171 0.6625121034291861 1.0 1.0 72 P00403,P47985,Q70HW3,Q5JPH6,O43676,O75306,Q9HC21,O43819,Q00325,O96000,P03886,O75648,Q96CU9,Q9UJS0,Q5JTZ9,Q6P4A7,Q9Y6M9 17 +Xerostomia 0.4473521704032258 0.4361593715482557 0.6627211031875235 1.0 1.0 16 Q15165,P35637,P50995,Q92804 4 +Squamous cell carcinoma of the skin 0.427502671891688 0.4355083518149821 0.6631934781156676 1.0 1.0 5 P19447,P18074,Q92889,P02545 4 +Abnormal circulating estrogen level 0.4398462849067764 0.4355049004172728 0.6631959827804816 1.0 1.0 11 P16435,Q969G3 2 +Broad nasal tip 0.4338093895920997 0.4350795106744373 0.6635047151488473 1.0 1.0 48 P61978,O43924,Q969G3,O14936,O95831,P51812,O43292,Q9Y487 8 +Spastic gait 0.4510056535227295 0.4342649608358576 0.6640960451646944 1.0 1.0 20 Q15041,Q9NVI7,P48643,P40818,Q9Y619 5 +Widened subarachnoid space 0.4536191950761784 0.4332721092319716 0.6648170978835466 1.0 1.0 25 Q7L7X3,P03886,O95831,P51812,Q92947 5 +Reduced visual acuity 0.282540831488058 0.4322586639836226 0.6655534265779828 1.0 1.0 98 O43676,Q9NZJ7,O75306,Q9Y4W6,Q9H061,P36404,O96000,Q969G3,P49327,P03886,P68371,Q96CU9,Q8NHS3,Q9NZ08,P01889,O60313,Q9Y6M9 17 +Abnormality of the inner ear 0.4351932712894903 0.4312877301020404 0.6662591708432772 1.0 1.0 9 Q9Y619 1 +Abnormal abdomen morphology 0.2814506865619651 0.4283422474920683 0.6684019648077748 1.0 1.0 191 O75880,O43676,Q9NZJ7,P03886,P21964,P23786,Q9Y619,P01889,Q15392,Q92947,P53992,Q5JPH6,Q96HY6,Q9NZ08,Q06124,P15260,Q9Y3Z3,Q9HC21,O96000,Q96A33,O14936,Q9UGP8,P40855,Q9UJS0,Q9Y6M9,Q15067,Q9NVI7,O43772,Q9BT22,Q9Y285,P09601,O75648,Q96CU9,Q96J02,P31751 35 +Optic atrophy 0.2791926157977157 0.4272169331581334 0.6692213289464848 1.0 1.0 160 Q9NZJ7,O43819,O96028,P03886,P21964,O76024,P01889,P00403,P53992,Q9Y4W6,Q15042,P31939,Q9P0J0,Q9BPX6,O60313,O43292,Q7KZN9,Q9HC21,Q9Y263,O14936,P40855,Q8NHS3,P51812,Q02750,Q15067,Q9NVI7,O75306,Q9H061,Q3ZCQ8,Q96PU5,Q96CU9 31 +Wide intermamillary distance 0.4498647468639319 0.4255408540926323 0.6704424462316796 1.0 1.0 21 P07437,P23786,Q06124 3 +Knee flexion contracture 0.4512707903701088 0.4239629076671587 0.6715928646901446 1.0 1.0 24 Q96AY3,P37268,P23786,Q86XL3,Q8TD16,Q7LGA3 6 +Slanting of the palpebral fissure 0.2791079702132284 0.42385309894894 0.6716729505715258 1.0 1.0 161 Q03164,P21964,Q86XL3,Q15392,Q9Y487,P53992,P61978,Q9BW83,O75179,Q7LGA3,P07437,Q06124,P42858,O14936,P40855,P51812,O75844,Q02750,O75648,P16435 20 +Congenital nystagmus 0.4444622361343796 0.4234846599817258 0.6719416883373752 1.0 1.0 16 O75648,P42858 2 +Neurofibrillary tangles 0.4216182615268464 0.4222424926137353 0.672848028601255 1.0 1.0 4 Q9Y287,O15118 2 +Gastroesophageal reflux 0.282128164238224 0.4208996955069609 0.6738283275769588 1.0 1.0 115 Q03164,P12235,Q9NZJ7,Q01105,O96028,Q7L7X3,P21964,Q9Y619,Q8IZA0,O15269,P53992,Q9Y4P3,Q96A33,Q9UGP8,P55795,O43175,Q96PU5,Q96J02,P16435 19 +High narrow palate 0.4510099525713297 0.4195876807055033 0.6747866894652914 1.0 1.0 26 Q06124,P61978,P23786,Q9Y619,P16435 5 +Abnormal globus pallidus morphology 0.4278692513368763 0.4179105705101226 0.6760125037263947 1.0 1.0 7 O43819,Q92947 2 +Ventricular hypertrophy 0.4490933439278715 0.4169143356505657 0.6767410674307743 1.0 1.0 34 O75880,P00403,P12235,Q07021,O43772,P13807,P03886,P23786,P46976,O75844 10 +Abnormal gallbladder morphology 0.4506724271882377 0.4167337701821146 0.6768731504843919 1.0 1.0 29 P47985,P53992,Q9NZJ7,Q9Y4P3,Q96A33,P21964 6 +Abnormal circulating bilirubin concentration 0.4503564326057752 0.4164841558838706 0.6770557588992494 1.0 1.0 26 Q9UGP8,O14936,O75648,P23786,P40855,P55263,Q9UJS0 7 +Hallux valgus 0.4394455799794065 0.4134851676841299 0.6792511872313831 1.0 1.0 14 Q15233,Q9Y4P3,Q96J02 3 +Abdominal distention 0.4420850737496463 0.4131261783567697 0.6795141705262311 1.0 1.0 16 O75648,Q96HY6,Q9NZJ7 3 +Abnormality of the cerebral subcortex 0.2722964730170475 0.4130079581255344 0.679600783160468 1.0 1.0 315 Q03164,P12235,Q9NZJ7,Q01105,Q08J23,O43819,O43924,O96028,Q7L7X3,P03886,P23786,Q9Y619,Q86XL3,Q5JTZ9,Q15392,Q92947,P00403,Q5JPH6,P61978,Q9NZ01,Q969G3,O95831,Q9BPX6,Q9UBX3,O60313,Q7LGA3,P07437,Q9BVA1,Q7KZN9,Q96N66,Q9Y3Z3,Q9HC21,P42858,Q9Y263,Q96A33,O14936,P48449,P51812,Q15067,Q9NVI7,O43175,O75306,Q9Y285,Q3ZCQ8,O75648,Q96PU5,Q96CU9,Q9BUK6,P37268,Q9Y320 50 +Flat forehead 0.416482493466758 0.4125069118107685 0.6799679156647824 1.0 1.0 3 Q13555 1 +Abnormal peripheral nervous system physiology 0.427842597058266 0.411589618032551 0.6806402424579776 1.0 1.0 49 O15269,Q9NZJ7,Q8TB36,Q15120,O95831,Q9Y619,Q99720,P04792,O60313 9 +Abnormal upper limb bone morphology 0.2774872774808727 0.411369602058089 0.6808015400515148 1.0 1.0 87 Q96AY3,Q02750,O00116,Q06124,Q08J23,P42858,O43924,Q9Y4P3,O96028,O75648,Q32P28,P51812,P16435,Q7LGA3,O75844 15 +Increased bone mineral density 0.4473779365549296 0.4110180280120518 0.6810593154900588 1.0 1.0 22 Q02750,Q9Y4P3,Q13126,Q15392,Q15813 5 +Migraine 0.4471904858281242 0.4101626455221021 0.6816866407332136 1.0 1.0 22 P00403,P12235,P03886,Q9NZ08,P01889,O60313 6 +Aplasia hypoplasia involving the skeleton 0.2712945775747197 0.4083454649766082 0.6830200649610798 1.0 1.0 268 Q03164,P13073,Q08J23,O43924,O96028,P21964,Q9Y619,Q86XL3,Q15392,O15228,Q96AY3,P53992,Q15042,P54886,Q969G3,O75718,Q7Z4L5,O95831,Q96HY6,P38435,Q7LGA3,Q15813,Q13555,P07437,Q06124,P15260,O75874,Q9HC21,P42858,Q9Y4P3,Q9Y263,Q96A33,O14936,P40855,P51812,O75844,P55795,Q02750,O00116,Q9NVI7,O43175,Q9BT22,P48735,O75648,Q32P28,Q96PU5,Q9BUK6,P37268,P16435 49 +Horizontal nystagmus 0.4457366310160446 0.4068107712382248 0.6841469750429683 1.0 1.0 21 Q69YN2,Q9NZJ7,Q9H061,P54886,O95831,O60313 6 +Shallow orbits 0.427164193483661 0.4064589932472555 0.6844053812902668 1.0 1.0 8 O75844 1 +Demyelinating peripheral neuropathy 0.4384091395005681 0.4029675793329545 0.6869720750292472 1.0 1.0 15 Q13217,P03886,Q9Y3Z3,Q9Y4W6 4 +Hemivertebrae 0.4317334485370698 0.4014961152506955 0.6880548977065128 1.0 1.0 11 P16435,O60216,Q9Y619,Q9UM00 4 +Aphasia 0.4446827671711174 0.4010248577802774 0.6884018225758255 1.0 1.0 36 P00403,P53992,P42858,P03886,P21964,O75648 6 +Atrophy degeneration involving the corticospinal tracts 0.4309327931498911 0.3981791992992078 0.6904980975882349 1.0 1.0 11 P35637 1 +Serositis 0.44093876630186 0.3978778551628124 0.6907202243486719 1.0 1.0 18 Q9BW27,Q14C86,Q9NZ08,P49327,Q8NFH4,Q12769,Q8N1F7,P01889 8 +Abnormality of adrenal physiology 0.4466608667165239 0.397624395286006 0.6909070752911397 1.0 1.0 30 O95470,Q969G3,P40855,Q13423,P16435 5 +External ear malformation 0.434134846577413 0.3974416538052105 0.6910418042265671 1.0 1.0 13 P07437,P40855,Q15813 3 +Abnormality of the palpebral fissures 0.2797110203081001 0.3972456586114057 0.6911863155392526 1.0 1.0 191 Q03164,Q08J23,P21964,Q9Y619,Q86XL3,Q15392,Q9Y487,P53992,P61978,Q9BW83,O75179,Q7LGA3,Q13555,P07437,Q06124,P42858,Q9Y4P3,O14936,P40855,P51812,O75844,P55795,Q02750,Q9NVI7,O75648,P16435 26 +Downslanted palpebral fissures 0.2804216693056095 0.3967779336052607 0.6915312243226288 1.0 1.0 119 Q03164,P53992,Q06124,P61978,P42858,P16435,O14936,Q9BW83,O75648,P21964,Q9Y487,P51812,Q15392,O75844 14 +Delayed closure of the anterior fontanelle 0.4320587591424491 0.3956270608255934 0.692380170903081 1.0 1.0 12 P51812,P40855,Q9Y487 3 +Abnormal arterial physiology 0.4435539165046315 0.3907180886312185 0.6960056268272217 1.0 1.0 23 Q9Y3Z3,Q9Y4P3,Q9NZ08,P01889,O75844 5 +Abnormality of the septum pellucidum 0.4444331493706144 0.3907146574172772 0.6960081633473731 1.0 1.0 33 Q9BVA1,Q96N66,Q08J23,Q9NZ01,Q15392 5 +Distal arthrogryposis 0.4133344200214418 0.3894623999612898 0.6969341198203747 1.0 1.0 4 P42356,Q96A33 2 +Tongue fasciculations 0.4282876070059853 0.3872731873593072 0.6985539732067458 1.0 1.0 11 P51114,O95831 2 +Rimmed vacuoles 0.4330552475448665 0.3863849812463965 0.6992115713856055 1.0 1.0 14 P31483,P50402,P22626,O14979 4 +Colitis 0.4198765728789834 0.3857284079050782 0.6996978215093894 1.0 1.0 7 P49327,Q6PGP7 2 +Abnormal femoral head morphology 0.4350618953534748 0.3828936558760868 0.7017986154557856 1.0 1.0 16 O95831 1 +Erythroid hyperplasia 0.4056939501779303 0.3814314761810456 0.7028831085917482 1.0 1.0 2 Q86SX6 1 +Hypertriglyceridemia 0.4379098407730653 0.3800183030078659 0.7039318287341763 1.0 1.0 19 P50402,P31751,Q9Y285,O95470 4 +Optic nerve hypoplasia 0.4343748330125767 0.3799669109942366 0.7039699775317976 1.0 1.0 16 Q9NVI7,P61978,Q9UHX1,Q15058,O14936,O75312,P37268,P49454 8 +Motor regression 0.4049822064056877 0.3787058514236022 0.7049063076654756 1.0 1.0 2 P51659 1 +Fat malabsorption 0.4154800783371066 0.3772901122560629 0.7059580194558159 1.0 1.0 6 Q14739,Q96A33,Q9Y3E5 3 +Relative macrocephaly 0.4420226812566089 0.3769417600070083 0.7062168865049607 1.0 1.0 32 P42858,O75648,Q96J02,Q15392,O75844 5 +Abnormal peripheral myelination 0.4420871765543467 0.3763834838227465 0.7066318228257782 1.0 1.0 27 P03886,O15269,Q92947,Q9NZJ7 4 +Abnormally lax or hyperextensible skin 0.4411902165532379 0.3745108254512519 0.708024304105763 1.0 1.0 33 Q02750,P07437,Q06124,P54886,Q9Y4P3,O96000,P51812,Q9Y487 8 +Neonatal hypoglycemia 0.4250774496589095 0.3741481507855024 0.7082940967162663 1.0 1.0 11 O43772,Q9BYW2,Q9UKG1,Q9UJX6,P31751 5 +Decreased circulating igg level 0.4210582939303116 0.3735295498654278 0.7087543565740613 1.0 1.0 9 P49327,P13051 2 +Abnormal venous morphology 0.4396866667764042 0.3731987835633882 0.7090005014607461 1.0 1.0 23 P21964,P53992,Q9Y487 3 +Cessation of head growth 0.4166478736769936 0.3729382141834141 0.7091944296151023 1.0 1.0 7 Q9Y263 1 +Abnormal atrioventricular valve morphology 0.4413114328644104 0.3722975166962313 0.7096713473452145 1.0 1.0 31 P53992,Q06124,P21964,O75844,P51812,P55795 6 +Abnormality of the anterior fontanelle 0.4413725237483688 0.3722044098114571 0.7097406630422562 1.0 1.0 28 Q08J23,O75718,Q32P28,Q9Y619,P51812,P16435,Q9Y487 7 +Young adult onset 0.426290988181112 0.3718093625582426 0.7100347923421475 1.0 1.0 12 Q9NZJ7,P31483,O15118,Q9H269,P36551,P38435,Q14566 7 +Coarse hair 0.4323587148921777 0.3714114600954213 0.7103310911406975 1.0 1.0 16 Q06124,Q9Y487,Q96A33 3 +Lens subluxation 0.4058383766464954 0.3711007302332873 0.7105625071562711 1.0 1.0 3 Q9Y467,Q99496 2 +Neoplasm of the respiratory system 0.4260778367346926 0.3709367797949902 0.7106846199754455 1.0 1.0 12 Q01844,Q9UJX6,O96017,P30154 4 +Abnormal macroscopic urine appearance 0.434364072619845 0.3693554226717015 0.7118628200418409 1.0 1.0 18 Q14C86,P23786,Q8NFH4,P36551,Q8N1F7 5 +Axonal degeneration regeneration 0.4130785287047869 0.3678964178466025 0.7129504713549917 1.0 1.0 6 Q8TB36 1 +Mortality aging 0.2738949155251406 0.3678003418510093 0.7130221141026973 1.0 1.0 87 Q15067,O43175,Q9NZJ7,Q9BT22,Q9HC21,O43819,Q9Y4P3,O96000,P16435,P51114,O75718,P40855,P51812,Q5JTZ9,O75844 15 +Abnormality of adrenal morphology 0.4388917524155271 0.3646866868009484 0.71534529758345 1.0 1.0 25 O75844,P16435,P40818,P48735 4 +Impaired t cell function 0.4182328810184351 0.3622641867160184 0.7171546180436263 1.0 1.0 9 P21964 1 +Decreased muscle mass 0.4277267991833909 0.3578811532801019 0.7204322553742024 1.0 1.0 15 Q9Y285,P46976,Q9Y487 3 +Cerebral palsy 0.4191014086163274 0.3577252504967373 0.7205489347400789 1.0 1.0 10 P48735,Q9BVA1 2 +Dyskinesia 0.4094777840022973 0.3542996151670516 0.7231143561216271 1.0 1.0 53 Q96N66,O43819,Q08J23,Q9NZ01,O14936,P03886,Q9BPX6,Q9UBX3 8 +Thickened helices 0.4068804916281993 0.3540937049893743 0.7232686595613895 1.0 1.0 5 Q06124 1 +Abnormal spermatogenesis 0.4247724443349102 0.3519789248427283 0.7248540679331288 1.0 1.0 14 Q13423,P16435,P51809 3 +Abdominal pain 0.3207136933198778 0.3504140944599076 0.7260279502793865 1.0 1.0 77 Q70HW3,Q14C86,Q8N1F7,P35637,Q9Y4P3,Q9UGP8,O14936,P49327,Q8NFH4,P23786,P40818,Q13423,Q9NZ08,P01889,Q14566 15 +Cerebral calcification 0.4364001992714391 0.3488766870034167 0.7271818879318146 1.0 1.0 28 O43175,Q9Y3Z3,P03886,P23786,O60313 5 +Functional abnormality of the gastrointestinal tract 0.2700919473485578 0.3474242952861126 0.7282725837366604 1.0 1.0 254 Q03164,P12235,Q9NZJ7,Q01105,O43819,O96028,O15118,Q7L7X3,P49327,P03886,P21964,O76024,P36551,Q9Y619,P01889,Q92947,P00403,Q8IZA0,O15269,P53992,Q9NXN4,P61978,Q9Y4W6,P54886,Q9NZ08,O60313,Q6PGP7,Q15813,P15260,O75874,Q9BUF5,P42858,Q9Y4P3,Q9Y263,Q96A33,Q9UGP8,Q99720,Q9UJS0,P55795,Q9BQP7,Q02750,Q15067,O43175,O75306,P35637,P48735,Q96PU5,Q96J02,P16435 49 +Abnormality of cardiovascular system electrophysiology 0.2734440370725145 0.3473227031152974 0.7283488965567464 1.0 1.0 90 Q9BQP7,O75880,P47985,P50402,P00403,Q06124,P12235,Q9NZJ7,O43772,O75306,Q8TB36,O43819,Q9Y4P3,P03886,P23786,P40855,P01889,P46976 18 +Fatigue 0.3197081337145682 0.3408115371493175 0.7332454645121591 1.0 1.0 77 Q9H3L0,P12235,Q70HW3,Q07021,Q9NZJ7,P35637,Q92889,P49327,O60313,Q9Y6X9,Q53H12,P40818,Q15165,Q13423,Q9NZ08,P01889,Q92804 17 +Abnormality of pain sensation 0.4329417297699916 0.3402119814530178 0.7336968958924825 1.0 1.0 24 O15269,P61978,P48643,O95831,P04792 5 +Proximal muscle weakness in upper limbs 0.4162746822666073 0.3388080292036053 0.7347543522350584 1.0 1.0 11 P50402,O95140,Q9Y6X9,P36551 4 +Delayed gross motor development 0.2730702310258418 0.3381398589910832 0.7352577946196037 1.0 1.0 91 Q03164,P61978,Q96N66,Q01105,Q15233,Q15042,P42858,P35637,Q9UJX6,O14936,Q3ZCQ8,O75648,P49589,Q9Y6X9,P48449,Q99720,Q7LGA3 17 +Scapular winging 0.4299721553183053 0.3371421652171841 0.7360097329202173 1.0 1.0 21 O60313,Q06124,Q9Y487 3 +Aplasia hypoplasia of the extremities 0.2743966270010586 0.3351339075492712 0.7375240758312951 1.0 1.0 166 Q03164,Q08J23,Q9Y619,Q15392,Q96AY3,Q969G3,O75718,Q7Z4L5,O95831,Q96HY6,Q7LGA3,Q13555,P15260,P42858,Q96A33,O14936,P51812,O75844,O00116,O43175,P48735,O75648,Q32P28,P16435 24 +Cutis laxa 0.4309550383270022 0.3343369336833924 0.7381253232995353 1.0 1.0 23 Q02750,P54886,Q9Y4P3,O96000,P51812,Q9Y487 6 +Congenital malformation of the right heart 0.4065363986623261 0.3337184333791855 0.738592038428904 1.0 1.0 7 P01889 1 +Abnormality of lower limb joint 0.2717035855149096 0.3329529679749771 0.7391697855703105 1.0 1.0 148 Q9Y4R8,Q9NZJ7,O96028,P49589,P21964,P23786,Q9Y619,Q15041,Q86XL3,Q9Y487,Q96AY3,P53992,P54886,O75718,O95831,Q96HY6,Q7LGA3,P08236,P42858,Q9Y4P3,Q96A33,O75312,Q8TD16,O75844,Q02750,Q9UJX6,Q96PU5,P37268,P16435,Q92889 30 +Receptive language delay 0.4200409236560166 0.3327132258793532 0.7393507650139923 1.0 1.0 14 O75648,P42858 2 +Absent facial hair 0.4122648656731844 0.3307673637005237 0.7408202145330323 1.0 1.0 10 O75844 1 +Arteriovenous malformation 0.4028629759786531 0.3287489948937781 0.742345418166737 1.0 1.0 6 P08236,Q92889 2 +Recurrent fractures 0.432062138212726 0.327686444111385 0.7431487540118697 1.0 1.0 30 Q96AY3,Q13126,P48735,O75718,Q32P28,P40818,P16435 7 +Hepatic failure 0.4279417626677778 0.3270035413998434 0.7436652066901859 1.0 1.0 39 O43772,P03886,O75648,P23786,Q9Y619,P01889 6 +Ectopic calcification 0.415508616811779 0.3264560488864825 0.7440793372326369 1.0 1.0 48 P00403,P08236,O00116,O43175,O00429,Q9Y3Z3,Q92889,P03886,P23786,P40855,P38435,O75844,O60313,O15228 14 +Glioma 0.4149399414851201 0.3261391507306483 0.744319076999203 1.0 1.0 12 P48735,Q9UJX6,O75874,O96017 4 +Somatic sensory dysfunction 0.2699356506487093 0.3258481438210757 0.744539251347839 1.0 1.0 86 O15269,P61978,Q9NZJ7,P04792,Q13217,Q8TB36,O43819,P54886,P48643,P49327,Q15120,O95831,Q96BR5,Q9Y619,Q9BUK6,Q9Y6X9,Q9NZ08,P01889 18 +Anonychia 0.4146613066420086 0.3250392659954214 0.7451513538202854 1.0 1.0 12 P16615 1 +Aplasia hypoplasia of the nipples 0.417589645352864 0.3228488228300236 0.7468097359035384 1.0 1.0 14 P07437,Q96A33 2 +Subcutaneous nodule 0.4232365302841255 0.3223159042107433 0.7472133857051511 1.0 1.0 18 Q06124,O75874,P35637,P49327,P48735,Q9NZ08,P01889 7 +Progressive gait ataxia 0.4076340149034618 0.3209105745044735 0.7482781601388151 1.0 1.0 9 P07602,P54886,Q9NZJ7 3 +Incisor macrodontia 0.420180834842584 0.3208275828466675 0.7483410553645686 1.0 1.0 16 O75648,P42858 2 +Abnormal incisor morphology 0.420180834842584 0.3208275828466675 0.7483410553645686 1.0 1.0 16 O75648,P42858 2 +Neoplasm of head and neck 0.4050052584606703 0.3192421189877658 0.7495429202484969 1.0 1.0 8 O60216,P21912 2 +Upper motor neuron dysfunction 0.2683067194496877 0.3167911146233797 0.7514021067425789 1.0 1.0 321 Q9Y4R8,Q9NZJ7,Q01105,Q08J23,O43819,O15118,Q7L7X3,P48643,P03886,P49327,P49589,Q9Y619,Q15041,Q86XL3,P01889,Q5JTZ9,Q92804,Q15392,Q92947,Q9Y487,P00403,P22626,Q9NXN4,Q5JPH6,Q9Y4W6,Q15042,Q9Y287,P54886,Q9NZ01,Q969G3,Q9P0J0,O95831,P40818,Q13423,Q9NZ08,Q9UBX3,O60313,O43292,Q15813,Q7KZN9,Q9BVA1,P51648,Q96N66,Q9Y3Z3,P42858,Q9Y4P3,Q9Y263,O14936,Q9Y6X9,P40855,Q8NCW5,Q99720,P51812,Q8TD16,Q6IA86,Q15067,Q9NVI7,O43175,O75306,Q13217,P35637,Q9UJX6,Q3ZCQ8,Q96B26,Q15165,Q96CU9,Q6DKK2,Q92889,Q9Y320 69 +Dysphagia 0.2744982928661271 0.3166404731019165 0.7515164216726147 1.0 1.0 130 Q03164,P12235,Q9NZJ7,Q01105,O43819,O15118,Q7L7X3,P03886,O76024,P01889,Q92947,Q8IZA0,Q9NXN4,Q9Y4W6,O60313,O75874,Q9BUF5,P42858,Q9Y263,Q99720,Q9BQP7,Q15067,O75306,P35637,P48735 25 +Ophthalmoparesis 0.3641488374192075 0.3160834803844153 0.7519391451937016 1.0 1.0 66 P00403,Q7KZN9,P12235,Q9BQP7,Q5JPH6,Q9Y4W6,O75306,O43819,Q969G3,O76024,P03886,Q96CU9,P01889,Q9BPX6,O60313 15 +Hypopigmented skin patches 0.4248664992041756 0.3152678848335684 0.7525582667555955 1.0 1.0 21 Q8IZA0,P53992,Q9NZJ7,Q15437,P21912,P07602,P49327,P42345,P21964,Q92889 10 +Low set posteriorly rotated ears 0.3745279046077994 0.3143519759675655 0.7532537262973285 1.0 1.0 63 Q02750,P07437,Q06124,Q15042,Q08J23,O43924,O96028,Q9BW83,Q9Y4P3,Q9Y263,P16435,P40855,Q96J02,P37268,Q15392 15 +Flat face 0.4245031445380339 0.3137249501176279 0.7537299493403253 1.0 1.0 21 Q13555,P07437,Q03164,P08236,P40855,Q9Y487 6 +Morphological abnormality of the pyramidal tract 0.421139910202964 0.3136382378509618 0.7537958142574017 1.0 1.0 18 Q9Y619,P35637,O95831 3 +Abnormal enchondral ossification 0.4253695427456307 0.3135256694332308 0.7538813216658284 1.0 1.0 22 O00116,O96028,Q96HY6,P40855,Q9Y619,P38435 6 +Spasticity 0.2669560984852617 0.3107092739396519 0.7560216464045337 1.0 1.0 266 Q9Y4R8,Q9NZJ7,Q01105,Q08J23,O43819,O15118,Q7L7X3,P48643,P03886,Q9Y619,Q15041,Q86XL3,Q5JTZ9,Q92804,Q15392,Q92947,Q9Y487,Q9NXN4,Q5JPH6,Q9Y4W6,Q15042,Q9Y287,P54886,Q9NZ01,Q9P0J0,O95831,P40818,Q9UBX3,O60313,O43292,Q15813,Q7KZN9,P51648,Q96N66,Q9Y3Z3,P42858,Q9Y4P3,Q9Y263,O14936,Q9Y6X9,P40855,Q99720,P51812,Q8TD16,Q6IA86,Q9NVI7,O43175,O75306,P35637,Q9UJX6,Q3ZCQ8,Q96B26,Q15165,Q96CU9,Q6DKK2,Q92889,Q9Y320 57 +Loss of speech 0.4217211960237003 0.3063143671158414 0.7593653012635107 1.0 1.0 20 O15118,Q9Y3Z3,Q5JTZ9,Q9NZJ7 4 +Teratoma 0.3879949138535505 0.3048846576049811 0.7604540012631134 1.0 1.0 3 Q9UJX6 1 +Central nervous system cyst 0.4166483765654221 0.3048204691145126 0.7605028908791498 1.0 1.0 45 P07437,O43175,Q9Y285,P23786,Q9Y487 5 +Gastrointestinal hemorrhage 0.425974043004286 0.3025537041466147 0.7622300004112319 1.0 1.0 27 P53992,Q9UJS0,Q9UGP8,O76024,P21964,Q9NZ08,P01889 7 +Athetosis 0.4134822375470979 0.3000246090919746 0.7641583844757305 1.0 1.0 15 O14949,Q92947,Q96CU9 3 +Neoplasm by histology 0.2699020136179996 0.2996139230602511 0.7644716627511121 1.0 1.0 91 Q02750,P07437,P11802,Q6PGP7,Q06124,O75874,O43924,Q969G3,Q9UJX6,Q13126,P48735,P49327,Q15392,Q92804,Q92947,P51809 16 +Hyperostosis 0.4097529078632778 0.2987032113373533 0.7651665065695368 1.0 1.0 13 Q02750,P51812,P22626 3 +Abnormality of chromosome segregation 0.3918662236684502 0.2981677019611695 0.7655751713345584 1.0 1.0 5 Q15437,Q14739,O60566 3 +Pterygium 0.4056430187122872 0.2974892582400398 0.7660930076805277 1.0 1.0 11 Q96AY3 1 +Abnormal ilium morphology 0.4127395880043129 0.2970851038088358 0.766401536688351 1.0 1.0 15 P01889,O95831 2 +Abnormal circulating glutamine family amino acid concentration 0.3941349426566338 0.2964086579169385 0.766918014194107 1.0 1.0 6 O96000 1 +Genital neoplasm 0.4252071161668907 0.2959648981280219 0.7672568883226538 1.0 1.0 32 O75874,Q15437,Q9BYW2,Q01844,Q9UJX6,P21912,P48735,Q13423,O43684,P51809,O96017 11 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2744137040046563 0.2957353132368316 0.7674322267295279 1.0 1.0 203 Q03164,Q08J23,O43924,O96028,P21964,Q9Y619,Q86XL3,Q15392,O15228,P53992,Q15042,Q7Z4L5,O95831,Q96HY6,Q7LGA3,Q15813,P07437,Q06124,Q9HC21,P42858,Q9Y4P3,Q9Y263,O14936,P40855,P55795,O75844,Q02750,Q9NVI7,O43175,Q9BT22,O75648,Q96PU5,Q9BUK6,P37268,P16435 35 +Dystonia 0.269964769465179 0.2955318223079379 0.7675876466271421 1.0 1.0 151 Q9NZJ7,Q01105,Q08J23,O43819,O15118,Q7L7X3,P03886,P49589,Q5JTZ9,Q92947,Q9NXN4,Q5JPH6,Q9Y4W6,P54886,Q9NZ01,Q9BPX6,Q7KZN9,Q96N66,Q9Y3Z3,P42858,Q9Y263,O14936,Q99720,Q9H3L0,O14949,Q15067,O75306,P35637,Q96CU9,Q6DKK2 30 +Abnormal circulating gonadotropin concentration 0.4082303071376266 0.292802518893729 0.7696731027988553 1.0 1.0 13 P16435,Q969G3 2 +Extramedullary hematopoiesis 0.3841584548117093 0.2912204370520802 0.7708827331298522 1.0 1.0 3 P98175 1 +Abnormality of the antihelix 0.4015172470536314 0.2896647434825868 0.7720727310715896 1.0 1.0 10 Q08J23,P16435 2 +Focal dystonia 0.4138889954746032 0.2896339565218516 0.772096286387459 1.0 1.0 17 Q99720,Q9NXN4,P35637 3 +Joint laxity 0.3568416066617518 0.2887003806040801 0.7728106714169702 1.0 1.0 67 Q96AY3,P61978,Q969G3,Q96A33,Q32P28,Q96HY6,Q9Y619,Q9BUK6,P55795,Q9Y487 10 +Abnormality of the adrenal glands 0.3941173956419425 0.2885895630177241 0.7728954833430255 1.0 1.0 55 O75874,O95470,Q969G3,P48735,P40818,P40855,Q13423,P16435,O75844 9 +Acidemia 0.4030831267944744 0.2877781300506684 0.7735165792050995 1.0 1.0 11 P48735,Q92947 2 +Abnormality of the urethra 0.2727129264275991 0.2870580197285019 0.7740678953874005 1.0 1.0 111 Q02750,P07437,P51809,P53992,Q06124,Q08J23,Q9Y4P3,Q969G3,O96028,P21964,P48449,Q9Y619,P40855,P37268,P01889,P16435,Q9UBX3,O75844 18 +Primary gonadal insufficiency 0.3980637832361363 0.2848851510866019 0.7757321325240012 1.0 1.0 9 O76024,P51809 2 +Abnormal thorax morphology 0.2736896225367973 0.2838931891244822 0.7764922361481479 1.0 1.0 199 Q03164,P50402,Q08J23,P21964,Q9Y619,Q9Y487,Q96AY3,P53992,P61978,O75718,Q7Z4L5,O95831,Q96HY6,O60313,Q7LGA3,P07437,P51648,Q06124,P42858,Q9Y4P3,Q9Y263,Q96A33,P51812,O75844,P55795,Q02750,Q9NVI7,O75648,Q32P28,Q96J02,Q9BUK6,P16435 32 +Multifocal epileptiform discharges 0.4173596491786593 0.2837786112829519 0.7765800466995139 1.0 1.0 21 Q08J23,Q9UBX3,Q9NZ01,Q96N66 4 +Neoplasm of the larynx 0.3849715099715095 0.2837175634907758 0.7766268338776705 1.0 1.0 4 P43246,P04637,O96017 3 +Melanoma 0.4122463267274989 0.283082165162995 0.7771138528015555 1.0 1.0 17 P49959,P11802,Q06124,Q15437,P18074,P21912,Q92889,O96017 8 +Hypogonadotropic hypogonadism 0.4203374763274501 0.2822737996385728 0.7777335739023319 1.0 1.0 25 P00403,Q06124,Q9Y4P3,Q969G3,P03886 5 +Prominent digit pad 0.4146152868566682 0.2818493330246069 0.7780590414092736 1.0 1.0 19 O75648,P42858,P55795 3 +Epicanthus inversus 0.3809184763260935 0.2798490896759033 0.7795932876338914 1.0 1.0 3 O14974,Q16531 2 +Abnormal motor nerve conduction velocity 0.4122865965807427 0.2776897846873019 0.781250502951107 1.0 1.0 18 Q8TB36,P48643,O95140,Q9Y6X9,Q99720,P04792 6 +Pigmentary retinopathy 0.4182151302777759 0.2773400170433618 0.7815190350463372 1.0 1.0 39 P00403,Q7KZN9,Q15067,O75306,Q9BW83,Q9P0J0,O76024,P03886,Q9Y6X9,Q96CU9,Q9BUK6,Q8NHS3 12 +Streak ovary 0.3886416554547109 0.2766131034342257 0.7820772020783091 1.0 1.0 6 P51809 1 +Aplasia hypoplasia of the cerebral white matter 0.3955306103986629 0.2755718355132622 0.7828769443249983 1.0 1.0 9 P00403,P03886 2 +Abnormal fingertip morphology 0.4193043193954771 0.2752625200449998 0.7831145572589313 1.0 1.0 26 O75844,O75648,P42858,P55795 4 +Spastic paraparesis 0.4128128305606969 0.2745732977026678 0.7836440834473848 1.0 1.0 19 Q9Y4W6,Q9Y3Z3,P21912,Q9Y619,Q6DKK2,Q15813 6 +Prominent supraorbital ridges 0.395107418155034 0.2740253286358715 0.7840651569534138 1.0 1.0 9 P38159,P51812 2 +Proximal muscle weakness in lower limbs 0.4078979455113181 0.2718740722634561 0.7857188479051551 1.0 1.0 16 P50402,P12235,Q16637,P36551 4 +Cutaneous photosensitivity 0.411768919099341 0.2703820292862327 0.7868663639645084 1.0 1.0 19 Q9Y3Z3,Q06136,Q08J23,P04080,P36551,P37268 6 +Abnormal circulating dicarboxylic acid concentration 0.416826093417968 0.2703750327432427 0.786871746031722 1.0 1.0 39 Q9H3L0,Q9UGP8,O14936,P48735,O75648,P23786,P40855,P55263,P37268,Q9UJS0,Q92947 11 +Aplasia hypoplasia of the proximal phalanges of the hand 0.3750889679715378 0.2702697813967987 0.786952711505192 1.0 1.0 2 P42345 1 +Shortening of all distal phalanges of the fingers 0.3927674236298141 0.2655232112562274 0.7906064313754739 1.0 1.0 9 P51812 1 +Hereditary nonpolyposis colorectal carcinoma 0.3852459016393362 0.2646021435761284 0.791315968643235 1.0 1.0 6 P35222,O60566,P63167,P04637,O96017 5 +Pontocerebellar atrophy 0.3729537366548065 0.2630169207884369 0.7925375372459393 1.0 1.0 2 O60762 1 +Bone cyst 0.3758231648757746 0.2622874541746277 0.7930998336622339 1.0 1.0 3 P21912 1 +Hamartomatous polyposis 0.3758231648757746 0.2622874541746277 0.7930998336622339 1.0 1.0 3 P21912 1 +Abnormality of hair texture 0.4113093953970291 0.2619636389173509 0.7933494754151433 1.0 1.0 43 Q02750,Q9NVI7,Q06124,O43175,Q08J23,P04080,Q96A33,P49589,Q9Y487,O75844,P51812,P54802,P55795,Q6PGP7 14 +Atrophy degeneration affecting the brainstem 0.3940033080237975 0.2619239183365872 0.7933800990115509 1.0 1.0 10 Q13217,O60313 2 +Finger swelling 0.3722419928825664 0.2606150971246119 0.7943893461010749 1.0 1.0 2 P28070 1 +Heart block 0.4126560286410754 0.2602495041776281 0.7946713206171501 1.0 1.0 22 P46976,O43772,P23786,Q06124 4 +Annular pancreas 0.3752224991100058 0.260243624617594 0.7946758556233251 1.0 1.0 3 Q96T58,Q9Y4R8 2 +Rigidity 0.4002468745367224 0.2598632311126512 0.7949692744424859 1.0 1.0 50 P12235,Q9NZJ7,Q9BPX6,Q9Y3Z3,Q9Y287,P42858,Q9Y263,O14936,Q96CU9,Q15392,Q92947 11 +Deviation of the hallux 0.4160871278857164 0.2591226031620576 0.7955406454489338 1.0 1.0 27 O75648,P42858,Q7LGA3,Q96J02 4 +Abnormal oral frenulum morphology 0.3989852885398599 0.2577149037535655 0.7966269430204389 1.0 1.0 13 O75844 1 +Congenital sensorineural hearing impairment 0.3854143851069818 0.2563118395197744 0.7977100559283972 1.0 1.0 7 Q16740 1 +Diffuse mesangial sclerosis 0.403062307794739 0.2532221033971177 0.8000965869605716 1.0 1.0 16 Q9BW27,Q14C86,O95470,Q8NFH4,Q12769,Q8N1F7 6 +Spina bifida 0.4153057005263226 0.2511858096666946 0.8016704551819893 1.0 1.0 30 P53992,Q06124,O43175,Q9HC21,Q08J23,P21964 6 +Neoplasm of the breast 0.4104243600086216 0.2511557171222918 0.8016937200105885 1.0 1.0 22 P11802,O75874,P21912,P49327,P48735,O96017 6 +Abnormal renal physiology 0.2676615931506015 0.2500917443708047 0.8025164002017224 1.0 1.0 143 O43676,Q14C86,O43819,P49327,P03886,O76024,P23786,P01889,Q92947,P00403,Q9BW83,Q7Z4L5,Q8NFH4,Q9NZ08,Q9Y4P3,O96000,P40855,Q8N1F7,Q9Y6M9,P51809,O43772,O95470,Q9BT22,O75306,P09601,Q96CU9 26 +Periventricular cysts 0.3808344740570399 0.249264985822105 0.8031558139061046 1.0 1.0 6 Q9Y285 1 +Ovarian cyst 0.4002272618905819 0.2488002622982299 0.8035152882007166 1.0 1.0 15 Q15437,Q9BYW2,Q9Y4P3,P21912,P31751,P16435 6 +Macule 0.3851102983331625 0.2477569014924587 0.8043225030005163 1.0 1.0 56 Q02750,P16615,Q8WWQ0,Q06124,Q15437,Q15233,Q06136,Q96PZ0,P42858,Q92889,P21912,P42345,O75648,O75844,P01889,O43684,Q7LGA3,Q6PGP7 18 +Contractures involving the joints of the feet 0.4084434998356847 0.2474892682367836 0.8045295959332313 1.0 1.0 21 Q8IZA0,P50402,Q08J23,Q92889,Q8TD16,O60313 6 +Abnormal cortical bone morphology 0.3974711925764704 0.2451514011652244 0.8063392045455511 1.0 1.0 14 Q15058,Q9H4A3,Q9NSD9,P40855,Q86XL3,Q15813 6 +Cerebral cortical atrophy 0.2656865574631472 0.2442109551055976 0.8070674429458087 1.0 1.0 92 O43924,P03886,O76024,Q9Y619,P00403,Q15042,P54886,Q7LGA3,P42858,Q9Y4P3,Q9Y263,O14936,Q8TD16,P51812,Q02750,Q9H3L0,Q96B26,O75648,Q92889 19 +Abnormal biliary tract morphology 0.4074770122526696 0.2436318811519168 0.8075159345677212 1.0 1.0 21 Q5XKP0,Q9NZJ7,Q10713,P09601,P07602,P21266,Q9NSD9,Q96J02,Q92889 9 +Sloping forehead 0.4133806585745417 0.2434462387030643 0.8076597276754882 1.0 1.0 35 O43175,Q08J23,O14936,P23786,Q86XL3 5 +Scleral staphyloma 0.3732193732193778 0.2432691764757276 0.8077968808545912 1.0 1.0 4 P40939,P36404,Q969N2 3 +Emg abnormality 0.3577084944537914 0.2419518282930398 0.808817489759527 1.0 1.0 65 P50402,P12235,O15269,P42166,Q9NZJ7,P04792,Q8TB36,O43819,P51114,Q15120,P42167,Q16637,Q9BUK6,P22626,O60313,P46976 16 +Impaired tandem gait 0.3980840760487323 0.2407747432550313 0.8097297057827306 1.0 1.0 15 O75648,P42858 2 +Heterogeneous 0.4124130517267563 0.2404969152208857 0.809945054398411 1.0 1.0 36 Q9BQE5,P03886,P21964,Q9Y619,P01889,O75844 6 +Abnormal lactate dehydrogenase level 0.3977744916580806 0.2396216101156298 0.8106236103298106 1.0 1.0 15 P23786,Q5JRX3 2 +Sleep apnea 0.402446157150098 0.2391338326643173 0.8110018080207093 1.0 1.0 18 P51114,Q96A33 2 +Infantile spasms 0.4100983968435255 0.2390061171577469 0.8111008393844685 1.0 1.0 25 P03886,Q9UBX3,Q92947 3 +Duplication involving bones of the feet 0.403655044026485 0.238391300861156 0.8115776138755715 1.0 1.0 19 P53992,O43924,Q9Y263,Q7Z4L5,P21964 5 +Abnormal cerebral ventricle morphology 0.2710468691341253 0.2367752657136895 0.8128311410860292 1.0 1.0 198 Q9NZJ7,Q01105,Q08J23,O43819,O96028,Q7L7X3,P21964,P23786,Q86XL3,Q15392,Q92947,Q9Y487,P53992,Q15042,Q969G3,Q15813,P07437,Q9BVA1,P08236,Q9Y3Z3,Q9HC21,P42858,Q9Y263,O14936,O75312,P40855,Q8TD16,P51812,Q02750,O43175,O75306,Q9UJX6,Q96CU9,P16435,Q92889,Q9Y320 36 +Abnormality of the ureter 0.3726505013886292 0.2365770213442698 0.812984948506901 1.0 1.0 60 P53992,P61978,O14936,O76024,P21964,P23786,Q86XL3,P16435,Q7LGA3,O75844 10 +Cutis marmorata 0.4002150024544906 0.2363635431694159 0.8131505831057377 1.0 1.0 17 Q9Y3Z3,Q08J23 2 +Biparietal narrowing 0.3843490487064088 0.2356433266432807 0.8137094502140823 1.0 1.0 9 O43924 1 +Atrophy degeneration affecting the central nervous system 0.2641793542373829 0.2354298571119575 0.8138751146073426 1.0 1.0 259 O75880,P13073,Q9UM00,Q9NZJ7,Q01105,Q08J23,O43819,O43924,O15118,Q7L7X3,P48643,P03886,O76024,P49589,Q9Y619,P22626,Q5JTZ9,Q92804,Q92947,P00403,Q9NXN4,Q15042,P54886,Q9NZ01,O95831,O60313,Q7LGA3,P08236,Q96N66,Q9Y3Z3,P42858,Q9Y4P3,Q9Y263,Q96A33,O14936,Q16637,Q9Y6X9,P40855,Q8NHS3,Q99720,P51812,P55263,Q8NCW5,Q8TD16,Q02750,Q9H3L0,Q9BT22,O75306,Q13217,P35637,Q9UJX6,Q5JRX3,Q3ZCQ8,Q96B26,O75648,Q15165,Q6DKK2,Q92889,Q9Y320 59 +Freckling 0.3887115826846841 0.2351035542160874 0.8141283601418421 1.0 1.0 11 P11802,Q06124 2 +Tube feeding 0.3779268443241752 0.2348910463141411 0.8142932991822089 1.0 1.0 58 P61978,Q9NZJ7,Q96N66,P37268,Q08J23,P35637,Q9NZ01,Q7L7X3,O75648,Q96J02,Q99720 11 +Hydrocephalus 0.3600238575530611 0.234545570560917 0.81456145943566 1.0 1.0 64 Q02750,P53992,P08236,Q08J23,O96028,Q969G3,P16435,P21964,P23786,P40855,Q15392,Q92947 12 +Abnormal subarachnoid space morphology 0.4108032291325975 0.2344417353883641 0.8146420611382215 1.0 1.0 28 Q7L7X3,P03886,O95831,P51812,Q92947 5 +Hypoplastic fingernail 0.3942014951543925 0.2331139086501222 0.8156729548601664 1.0 1.0 14 P51812 1 +Broad finger 0.4110890597638906 0.2326529735657037 0.8160308888232706 1.0 1.0 30 Q08J23,P42858,O14936,O75648,P51812 5 +Thoracic aortic aneurysm 0.4110609654643024 0.231207947333117 0.8171532561859489 1.0 1.0 32 P42858,Q9Y4P3,O75648,P01889,Q7LGA3,O75844 6 +High pitched voice 0.3897306719964028 0.2311970457516479 0.8171617249892995 1.0 1.0 12 P07237,Q9Y6X9,Q92889,O75844 4 +Premature skin wrinkling 0.3986288615645286 0.2303779742937013 0.8177980748539788 1.0 1.0 17 Q02750,Q06124,O75844,Q9Y487 4 +Skin nodule 0.4043468838355197 0.226805957143212 0.8205746312807354 1.0 1.0 22 P11802,P16615,Q06124,O75874,Q92990,Q15437,P35637,P21912,P49327,Q9NSE4,P48735,Q9NZ08,P01889 13 +Intellectual disability severe 0.2679911798427455 0.2242142797488563 0.8225905726834051 1.0 1.0 117 Q01105,Q08J23,O96028,Q7L7X3,Q86XL3,P61978,Q15042,P31939,Q9NZ01,Q969G3,Q7KZN9,Q96N66,P42858,P51812,O14949,Q15067,O75306,Q3ZCQ8,Q96CU9,Q9Y320 20 +Functional abnormality of the middle ear 0.2667596427489946 0.2239879941306731 0.8227666452084299 1.0 1.0 85 P53992,P61978,P42858,O43924,O75648,P21964,O95831,P01889,P16435,O75844 10 +Macrodontia 0.396857283139247 0.2237423564500615 0.8229577856480459 1.0 1.0 17 O75648,P42858 2 +Malar prominence 0.3597864768683355 0.2199054389160672 0.8259448003525454 1.0 1.0 2 Q9Y4W2 1 +Dysplasia of the femoral head 0.3627625489498084 0.2191571117569777 0.826527663194137 1.0 1.0 3 Q96L58,O75431 2 +Abnormal hair quantity 0.2698229124763886 0.2189734210322107 0.8266707522708341 1.0 1.0 193 Q03164,Q06136,Q08J23,O43819,P49327,P03886,P49589,P36551,P01889,Q9Y487,P00403,Q15042,P54886,Q969G3,Q9BW83,Q9P0J0,P40818,Q6PGP7,P07437,P47985,Q7KZN9,P08236,Q06124,Q9Y263,Q96A33,O75312,P48449,P54802,O75844,P51809,Q02750,O43175,O75306,P04080,Q9UJX6,O75648,Q96CU9,Q9BUK6,P16435,Q92889 40 +Abnormality of the scrotum 0.4027101154177694 0.2176774867692319 0.8276804060229974 1.0 1.0 43 P07437,P42858,O75648,P46977,Q9Y619,P16435,Q7LGA3 7 +Prominent occiput 0.3813583981535279 0.2172416176441287 0.828020052851449 1.0 1.0 10 O43175 1 +Lower limb amyotrophy 0.3891309317019518 0.2147971867646756 0.8299254463451706 1.0 1.0 14 P04792,Q15120,Q9Y6X9,Q9NVI7 4 +Severe short stature 0.3994239891978842 0.2121007437397025 0.8320284394839841 1.0 1.0 21 Q15392,Q9Y619 2 +Neoplasm of striated muscle 0.369572897817763 0.2115377208321096 0.8324677011373725 1.0 1.0 6 O43684,O60566,O96017 3 +Rhabdomyosarcoma 0.369572897817763 0.2115377208321096 0.8324677011373725 1.0 1.0 6 O43684,O60566,O96017 3 +Abnormal esophagus physiology 0.2698311311292488 0.211477343408225 0.832514809766244 1.0 1.0 208 Q03164,P12235,Q9NZJ7,Q01105,O43819,O96028,O15118,Q7L7X3,P03886,P21964,O76024,Q9Y619,P01889,Q92947,Q8IZA0,O15269,P53992,Q9NXN4,Q9Y4W6,O60313,O75874,Q9BUF5,P42858,Q9Y4P3,Q9Y263,Q96A33,Q9UGP8,Q99720,P55795,Q9BQP7,Q15067,O43175,O75306,P35637,P48735,Q96PU5,Q96J02,P16435 38 +Hepatoblastoma 0.3747326356798304 0.2112199760070941 0.8327156237764142 1.0 1.0 8 Q969G3 1 +Nephropathy 0.3974956591292206 0.2096231241974709 0.8339618301099496 1.0 1.0 20 P00403,O76024,P03886,Q7Z4L5 4 +Abnormal pattern of respiration 0.265413360708898 0.2094918575946633 0.8340642910718707 1.0 1.0 155 O75880,Q9NZJ7,O43819,O43924,P03886,O76024,P23786,Q9Y619,P01889,Q92804,P61978,O95831,O60313,Q7KZN9,P47985,Q96A33,O14936,P51114,P51812,P46976,O75844,Q9BQP7,O43772,P35637,Q00325,O75648,Q96CU9 27 +Premature loss of teeth 0.381357167433473 0.2094351675887106 0.8341085416793195 1.0 1.0 11 O75844 1 +Brisk reflexes 0.3956737092443142 0.2079847887471115 0.8352408444716515 1.0 1.0 19 Q99720,P49589,P35637,Q5JRX3 4 +Hyperpituitarism 0.3951228361925678 0.2059266664334334 0.8368481950351407 1.0 1.0 19 P16435,Q969G3,Q9BUK6 3 +Abnormal morphology of the limbic system 0.3753733528756494 0.2050624605806526 0.8375233252652066 1.0 1.0 9 Q7L7X3 1 +Constipation 0.2808383149201391 0.2046603896031562 0.8378374697972466 1.0 1.0 82 P00403,Q03164,P12235,P53992,P61978,Q9Y4P3,P03886,P21964,O76024,Q13423,P37268,P16435,Q7LGA3,P55795 14 +Abnormality of fibula morphology 0.3774669481906059 0.2040253611525168 0.838333680394546 1.0 1.0 10 Q96HY6 1 +Abnormality of dental morphology 0.3825105207721023 0.2038646070934442 0.8384593036612942 1.0 1.0 54 P04080,P42858,Q96A33,O75648,Q9Y619,P51812,Q7LGA3,Q9Y487 8 +Skin dimple 0.3972322993004781 0.2037134026521392 0.8385774680174598 1.0 1.0 21 Q03164,P61978,Q08J23,Q9Y4P3,O96028 5 +Aortic regurgitation 0.3994249387709797 0.2033052995899502 0.8388964135547197 1.0 1.0 23 P54886,P49327,Q96PU5,Q9NZ08,P01889,O75844 6 +Cystinuria 0.3533807829181579 0.1999829793531382 0.8414938927436546 1.0 1.0 2 Q4J6C6 1 +Tip toe gait 0.3533807829181496 0.1999829793531129 0.8414938927436744 1.0 1.0 2 O75477 1 +Difficulty running 0.3785041917132201 0.199725888174012 0.8416949658493642 1.0 1.0 11 Q9BPX6,Q9Y6X9 2 +Abnormality of epiphysis morphology 0.3911097136713352 0.1989545749529488 0.842298278107465 1.0 1.0 49 O00116,Q06124,O96028,Q7Z4L5,O95831,Q96HY6,Q9Y619,P40855,P38435,P51812,P16435,Q7LGA3,O15228 13 +Tinnitus 0.3862666942365687 0.1978989022977146 0.8431241630326713 1.0 1.0 15 Q9NR28,O95831 2 +Bilateral polymicrogyria 0.3742302253330891 0.19323277409799 0.846776672383788 1.0 1.0 10 Q7L7X3,Q01105 2 +Abnormality of refraction 0.266130869704472 0.1917150033258571 0.8479654530327756 1.0 1.0 123 P12235,Q07021,Q08J23,O43819,Q9Y487,P61978,P54886,Q969G3,P68371,Q7LGA3,O43292,Q15813,Q13555,P51648,Q06124,P42858,Q9Y4P3,Q96A33,O14936,Q02750,Q15067,Q9NVI7,Q9UJX6,O75648,Q53H12,Q92889 26 +Nausea and vomiting 0.266063260405478 0.1900233391567186 0.8492908417290317 1.0 1.0 125 O43676,Q9NZJ7,P49327,P03886,P23786,P36551,Q9Y619,P01889,Q92804,P00403,Q8IZA0,P61978,Q969G3,Q13423,Q9NZ08,Q9Y4P3,O96000,Q9UJS0,Q9Y6M9,Q9BQP7,O43175,O75306,P35637,O75648,Q96CU9 25 +Eeg with continuous slow activity 0.3531505873976527 0.1892508906410544 0.8498961832921592 1.0 1.0 3 P55072,Q13501 2 +Collectionism 0.3531505873976527 0.1892508906410544 0.8498961832921592 1.0 1.0 3 P55072,Q13501 2 +Lack of insight 0.3531505873976527 0.1892508906410544 0.8498961832921592 1.0 1.0 3 P55072,Q13501 2 +Abnormal fear anxiety related behavior 0.265026736994963 0.1888224536036384 0.8502319729677068 1.0 1.0 107 P00403,Q03164,P53992,P42858,P35637,P03886,O75648,P21964,O76024,P40818,Q9BUK6,Q6DKK2,Q92804,Q7LGA3,P55795 15 +Hypergonadotropic hypogonadism 0.3853320474517376 0.1881238370229487 0.8507795754523566 1.0 1.0 16 Q9BQP7,P48449,Q16740 3 +Abnormality of the knee 0.311983944569501 0.1869547828801523 0.8516960858131033 1.0 1.0 75 Q96AY3,Q02750,P53992,P08236,P37268,Q9Y4P3,P21964,P23786,O95831,Q9Y619,Q15041,Q86XL3,Q96HY6,O75312,Q96PU5,Q7LGA3 16 +Pancreatic cysts 0.3554131054131062 0.1862923337804742 0.8522155189926304 1.0 1.0 4 Q9Y5S9,Q9UBS4,Q14697 3 +Renal tubular atrophy 0.3554131054131036 0.1862923337804663 0.8522155189926366 1.0 1.0 4 P57740,Q96AX1,Q8WUM0 3 +Insulin resistant diabetes mellitus 0.3670760734107007 0.1862637425827593 0.8522379390906996 1.0 1.0 8 O75844 1 +Focal onset seizure 0.3073550231674152 0.1847764723553012 0.8534043624172092 1.0 1.0 76 P00403,Q9BVA1,O43175,Q9NZJ7,Q96N66,Q08J23,Q9NZ01,Q7L7X3,O14936,P03886,Q9UBX3 11 +Distal lower limb amyotrophy 0.3727154009844193 0.1804663522318482 0.8567864677110963 1.0 1.0 11 P04792,Q15120,Q9Y6X9 3 +Apneic episodes precipitated by illness fatigue stress 0.3466192170818591 0.1797373669533042 0.8573587565481304 1.0 1.0 2 P53007 1 +Cranial hyperostosis 0.3717891979191364 0.1774407126740143 0.8591622305659545 1.0 1.0 11 P51812,P22626 2 +Advanced eruption of teeth 0.3716295710324675 0.1769208352873118 0.8595705725878036 1.0 1.0 11 O75844 1 +Abnormality of the helix 0.3985943690299773 0.176437156018142 0.8599505162271499 1.0 1.0 33 Q02750,P53992,Q06124,P21964,P23786,Q7LGA3,O75844 7 +X linked dominant inheritance 0.385052983429597 0.1749596517888162 0.8611113377077564 1.0 1.0 18 O14936,P51812,P55795 3 +Abnormal pons morphology 0.3877666537696854 0.1735880058876964 0.8621892588243041 1.0 1.0 20 Q9BVA1 1 +Sclerocornea 0.3565711891653537 0.1706857884368079 0.8644708380228794 1.0 1.0 6 P49454,O95202,O96028 3 +Hyperorality 0.3534022087637993 0.170587721651809 0.8645479531083116 1.0 1.0 5 Q13501,P55072,Q14203,Q05086 4 +Abnormality of the calvaria 0.2658251094718971 0.1701254316167433 0.8649114935084092 1.0 1.0 222 Q03164,P13073,Q01105,Q08J23,O43924,O96028,P21964,Q9Y619,P22626,Q15392,Q9Y487,O15228,Q96AY3,P53992,P61978,Q15042,P54886,P31939,O75718,O75179,O95831,Q6PGP7,P07437,Q06124,Q9Y3Z3,Q96A33,O14936,P40855,P55263,P51812,O75844,Q02750,Q15067,Q9NVI7,O43175,Q9BT22,Q32P28,Q96J02,P16435 39 +Cerebellar malformation 0.3869376595798978 0.1685652824441334 0.8661385903204417 1.0 1.0 48 P07437,O43175,Q969G3,P23786,P16435,Q9Y487 6 +Gastrointestinal inflammation 0.3830137424282254 0.1677923832123969 0.8667466148606731 1.0 1.0 18 P50851,O43175,P49327,P01889,Q6PGP7 5 +Generalized onset seizure 0.2594667174765593 0.1658823756678556 0.8682495175074418 1.0 1.0 93 Q9Y320,Q9NVI7,O43175,Q96N66,Q9NZJ7,P61978,Q08J23,P04080,Q9NZ01,Q9Y263,O14936,Q7L7X3,P03886,Q9Y619,Q8NHS3,P51812,O43292 17 +Dementia 0.3715945134089053 0.1656426087675513 0.8684382135057951 1.0 1.0 56 P00403,Q9NZJ7,P04080,Q9Y287,P42858,P35637,O15118,O76024,P03886,P22626,Q5JTZ9,O60313,Q92947,Q9Y487 14 +Irregular hyperpigmentation 0.3643107365888576 0.1656001652189627 0.8684716172618323 1.0 1.0 59 P07437,P16615,Q06124,Q06136,P42858,O75648,Q7LGA3,O75844 8 +Abnormality on pulmonary function testing 0.3823562497740972 0.1654981916166165 0.8685518730881094 1.0 1.0 18 Q9Y285,P01889,Q96J02 3 +External genital hypoplasia 0.2632982660712318 0.1652024367967759 0.8687846473335861 1.0 1.0 108 P07437,P51809,Q06124,O43175,O95470,Q9Y3Z3,Q9Y4P3,Q9BW83,O14936,P51114,P46977,P48449,Q9Y619,P16435,O75844 15 +Abnormality of the tongue 0.2866448965407349 0.1641315930398371 0.8696275514094904 1.0 1.0 80 P61978,O43924,Q969G3,Q96A33,Q9Y4P3,O75648,P51114,O95831,Q16637,P01889,Q7LGA3,O75844 12 +Hand tremor 0.367605140730992 0.163968694872131 0.8697557880984648 1.0 1.0 11 Q16637 1 +Global brain atrophy 0.3819013323051043 0.1639156384100187 0.8697975559440698 1.0 1.0 18 O43819,P35637,Q9NZJ7 3 +Renal dysplasia 0.3649940424435773 0.1634673730703744 0.8701504601037551 1.0 1.0 10 O75306,Q53EZ4,O43819,O14936 4 +Metaphyseal widening 0.3761970455643152 0.1633076666518478 0.8702761978238713 1.0 1.0 15 O95831 1 +Nasogastric tube feeding 0.3862727496785939 0.1630856831404784 0.8704509720796134 1.0 1.0 21 Q08J23,Q96N66 2 +Aplasia hypoplasia involving the vertebral column 0.3719311793955895 0.1630812589431641 0.8704544554467786 1.0 1.0 13 O95831 1 +Motor neuron atrophy 0.3885869907850242 0.1621763223964134 0.8711670049439992 1.0 1.0 23 P50995,P35637,Q16637,Q15165,Q99720,P22626,Q92804 7 +Intestinal polyp 0.3776611766392796 0.161681494579464 0.8715566779764781 1.0 1.0 16 P42892,Q15437,P21912,P42345,O43684,O96017 6 +Astrocytosis 0.353528153955805 0.1615647731185019 0.8716485997611692 1.0 1.0 6 P55265,P37198,P42345,P55072,Q13501 5 +Joint stiffness 0.384000906226638 0.1609155149269516 0.8721599424071806 1.0 1.0 49 Q96AY3,P50402,P08236,P51648,O75874,Q15042,Q9Y4P3,P48735,O76024,P01889,P16435,O75844 12 +Abnormal diaphysis morphology 0.3706517959966919 0.1600873711351466 0.8728122492465911 1.0 1.0 56 Q96AY3,Q02750,P08236,Q06124,Q9Y4P3,Q13126,O75718,Q32P28,Q96HY6,Q9Y619,P51812,P16435,Q7LGA3,Q9Y487,Q15813 15 +Distal amyotrophy 0.3836300452268354 0.1589639976392146 0.8736972388179969 1.0 1.0 49 Q9Y3E5,P48643,Q96BR5,O15269,Q8N2K0,Q9Y4W6,P31483,P04792,Q15813,P21912,Q9Y6X9,Q9BUK6,Q8TD16,Q99720,Q9NVI7,Q8TB36,P35637,Q15120,O95140,P43243 20 +Abnormal lower motor neuron morphology 0.3632612771214411 0.1580579732472337 0.8744111167442978 1.0 1.0 10 Q99720 1 +Lower limb hyperreflexia 0.3815907586392498 0.1571016990830338 0.8751646985368837 1.0 1.0 19 P13073,Q9Y4W6,Q15233,P54886,P40818,Q15041 6 +Generalized amyotrophy 0.387200464684904 0.157075936089077 0.8751850023624237 1.0 1.0 23 Q9BQP7,O43819,P35637,P49589,P22626 5 +Respiratory failure 0.365418920769981 0.1569431136714453 0.8752896810647963 1.0 1.0 58 Q9BQP7,Q70HW3,Q9NZJ7,Q9BT22,P35637,P23786,Q16637,Q9Y619,Q92804 9 +Abnormal 3rd finger morphology 0.3380782918149554 0.1553557474523922 0.8765408689389205 1.0 1.0 2 Q9Y3E5 1 +Unilateral ptosis 0.3380782918149494 0.1553557474523753 0.8765408689389338 1.0 1.0 2 Q9UHX1 1 +Platyspondyly 0.3919846838358052 0.15491359365891 0.8768894368322222 1.0 1.0 29 Q96AY3,P48735,Q32P28,O95831 4 +Antenatal onset 0.3595989671159616 0.1547429462689753 0.8770239715284067 1.0 1.0 9 Q9Y285 1 +Abnormality of the kidney 0.2590564615313176 0.1547373891301758 0.8770283527156992 1.0 1.0 293 Q9Y4R8,Q03164,Q07021,O43676,Q14C86,Q08J23,O43819,O43924,O96028,P49327,P03886,P21964,P23786,O76024,P36551,Q86XL3,P01889,Q15392,Q92947,P00403,P53992,P61978,Q15042,P54886,Q969G3,Q9BW83,O75718,Q7Z4L5,Q8NFH4,O75179,P40818,Q9NZ08,Q7LGA3,Q6PGP7,P11802,Q06124,Q92733,Q9Y4P3,O96000,Q9UGP8,O14936,O75312,P40855,Q8N1F7,Q9Y6M9,P51809,Q9BQP7,Q02750,O43175,O43772,O95470,Q9BT22,O75306,Q9UJX6,P09601,Q9UBS4,Q96CU9,Q12769,P16435,Q92889,Q9Y375,Q9UM00 62 +Abnormal adipose tissue morphology 0.3759753073673018 0.1547202746693706 0.8770418455925957 1.0 1.0 53 P50402,O43175,Q9Y3Z3,P42167,P40818,Q9BUK6,O75844,P31751,Q9Y487 9 +Hypoplastic labia majora 0.3620448742130861 0.1542942604474752 0.8773777226265322 1.0 1.0 10 Q9Y619 1 +Abnormal labia majora morphology 0.3620448742130861 0.1542942604474752 0.8773777226265322 1.0 1.0 10 Q9Y619 1 +Patent ductus arteriosus 0.285340836200281 0.1517357892289937 0.8793953282671172 1.0 1.0 80 Q02750,P53992,Q06124,O43175,Q6PGP7,P42892,Q9UM00,Q9Y4P3,Q969G3,Q9UJX6,P21964,Q96PU5,P40855,Q15392,Q92889,O75844 16 +Tapered finger 0.392840471366032 0.1516545947525227 0.8794593709737879 1.0 1.0 34 Q03164,Q06136,P23786 3 +Abnormal ovarian physiology 0.3852180013794172 0.149849026179891 0.8808837287108657 1.0 1.0 23 Q5JTZ9,O75844 2 +Azoospermia 0.3672591145436025 0.1480684343178916 0.8822887605759453 1.0 1.0 13 Q13423,P51809 2 +Dilation of lateral ventricles 0.3816176732948201 0.1465188998583068 0.8835117709932065 1.0 1.0 21 Q7L7X3,Q01105,Q9BVA1,Q92947 4 +Difficulty walking 0.3437787972073718 0.1440778765433656 0.885438974392696 1.0 1.0 65 Q9NZJ7,Q15041,P31483,Q969G3,P04792,Q9BPX6,O43292,Q9HC21,Q9Y3Z3,P42858,Q9Y6X9,Q8TD16,Q99720,P46976,Q15067,P35637,Q15120,Q9BUK6,Q92889 19 +Aortic aneurysm 0.3775417989247304 0.143610141472798 0.8858083319393648 1.0 1.0 51 P61978,Q9Y3Z3,P54886,Q9Y4P3,P42858,Q9UJX6,P49589,O75648,Q96PU5,P01889,Q7LGA3,O75844 12 +Breast carcinoma 0.3722079122124546 0.1435585481726219 0.8858490752731298 1.0 1.0 16 P48735,O96017,O75874,P21912 4 +Unusual infection by anatomical site 0.3584912430350817 0.1434597364129163 0.8859271079624722 1.0 1.0 10 Q9NZ08,P01889 2 +Papule 0.3756392392800816 0.1425354863927302 0.8866570514185492 1.0 1.0 18 P16615,Q92990,P49327,P38435,Q9NZ08,P01889,Q92889,O75844 8 +Aplasia hypoplasia of the thymus 0.3630243268264664 0.1420946008673062 0.88700528278877 1.0 1.0 12 P21964 1 +Abnormality of the thymus 0.3630243268264664 0.1420946008673062 0.88700528278877 1.0 1.0 12 P21964 1 +Severe global developmental delay 0.3694899057929284 0.1407942930473853 0.888032451644093 1.0 1.0 55 O43175,Q9BT22,Q9HC21,P42858,Q96A33,O14936,P03886,O75648,P40855,P55263,P51812,Q7LGA3 12 +Abnormality of the hypothalamus pituitary axis 0.3463166067953591 0.1402998830172677 0.8884230567494027 1.0 1.0 64 Q03164,O14654,Q15233,Q10713,Q9NSE4,O76024,P57740,P42356,Q969G3,P40818,Q96IJ6,Q15813,O75874,Q9UHX1,P51809,Q9Y285,Q9UBS4,P16435,P48735,Q9BUK6,Q9NRG9,Q92889,Q9UM00 23 +Abnormality of the ovary 0.367094762901076 0.1393446855723408 0.8891777803137113 1.0 1.0 56 P49327,P57740,Q5JTZ9,Q15437,Q9BW83,P40818,Q8WWQ0,Q06124,O75874,Q01844,Q9Y4P3,P21912,O75312,Q9NR50,O75844,P51809,O96017,P48735,P31751,P16435 20 +Abnormal bronchus morphology 0.3723460125821091 0.1376842984410135 0.8904899292325104 1.0 1.0 17 Q13432,Q96HY6 2 +Abnormality of the voice 0.2620732739789522 0.1358677333699647 0.8919258439320368 1.0 1.0 122 Q9BQP7,P53992,Q06124,Q9Y3Z3,P42858,P03886,O75648,P21964,Q96HY6,Q9Y487,Q6DKK2,O60313,O75844 13 +Abnormal cns myelination 0.261767917780253 0.1357590911747244 0.8920117320826544 1.0 1.0 119 Q7KZN9,Q15067,P51648,O43676,O43175,Q9NZJ7,O75306,Q9Y3Z3,O43819,P35637,O96000,P03886,O95831,Q96CU9,P40855,Q99720,Q7LGA3,Q9Y6M9 18 +Generalized hypotonia 0.2593263643621767 0.1350154108935021 0.892599689769284 1.0 1.0 306 O75880,Q03164,P13073,Q70HW3,P12235,O43676,Q9NZJ7,Q01105,Q08J23,O43819,Q8N511,O43924,O96028,O15118,P46977,P23786,Q9Y619,Q9BWD1,Q92947,Q9Y487,O15228,P61978,P54886,P31939,Q9NZ01,O95831,Q9UBX3,O43292,Q13555,P07437,Q7KZN9,Q96N66,Q96A33,P40855,P55263,P51812,Q9Y6M9,Q9H3L0,O14949,Q9NVI7,O43772,O95470,Q9BT22,Q9Y285,Q3ZCQ8,O75648,Q96CU9,Q9BUK6,Q96J02,Q6P4A7 50 +Persistent head lag 0.3472499070148691 0.1348464988442963 0.8927332407957398 1.0 1.0 7 Q15233,Q9NSD9 2 +Prematurely aged appearance 0.3881750225036138 0.1318834938830959 0.8950764445527564 1.0 1.0 35 Q02750,Q06124,Q15042,Q9Y4P3,Q13126,P49327,O75844,Q9Y487 8 +Hamartoma 0.3733472883329357 0.1290710130716904 0.8973014583385011 1.0 1.0 19 P11802,O75874,Q15437,Q02978,O43924,P21912,P48735,Q92947 8 +Abnormality of the gallbladder 0.3874910018457732 0.1290402404722313 0.8973258077002098 1.0 1.0 35 P47985,P53992,Q9NZJ7,Q9Y4P3,Q96A33,P21964,P40855 7 +Abnormality of the nasal septum 0.3419083926088907 0.128341539297467 0.8978786932964411 1.0 1.0 6 P51812 1 +Multiple joint contractures 0.3694487976693396 0.1282661192110271 0.8979383765426958 1.0 1.0 17 O75844 1 +Thin skin 0.3814645179396639 0.1278989288837687 0.8982289587122363 1.0 1.0 25 Q13126,O75844,Q9Y619 3 +Decreased circulating androgen concentration 0.3552077388727323 0.1259943712884975 0.8997363801301237 1.0 1.0 11 P16435,Q969G3 2 +Malrotation of small bowel 0.3304013015897901 0.1251814119829139 0.9003799325695407 1.0 1.0 3 O96028 1 +Abnormality of abdominal situs 0.3304013015897901 0.1251814119829139 0.9003799325695407 1.0 1.0 3 O96028 1 +Ectopia pupillae 0.3304013015897901 0.1251814119829139 0.9003799325695407 1.0 1.0 3 O96028 1 +Hypoplastic pubic rami 0.3304013015897901 0.1251814119829139 0.9003799325695407 1.0 1.0 3 O96028 1 +Rib segmentation abnormalities 0.3304013015897901 0.1251814119829139 0.9003799325695407 1.0 1.0 3 O96028 1 +Craniofacial asymmetry 0.3304013015897901 0.1251814119829139 0.9003799325695407 1.0 1.0 3 O96028 1 +Severe muscular hypotonia 0.3834218014248037 0.1246516651278568 0.9007993244781558 1.0 1.0 28 Q01105,Q7L7X3,O95831,P40855,Q92947 5 +Abnormality of the pulmonary vasculature 0.3863551265573803 0.124341906359368 0.9010445682607864 1.0 1.0 35 Q06124,P42858,O75718,O75648,Q15392,Q7LGA3 6 +Dyscalculia 0.3570082226728916 0.1238596594706582 0.901426394004334 1.0 1.0 12 P22626,P35637 2 +Breathing dysregulation 0.3278746885012532 0.1186766468951409 0.905531538850221 1.0 1.0 3 O75380,Q10713 2 +Decreased corneal reflex 0.3278746885012489 0.11867664689513 0.9055315388502296 1.0 1.0 3 Q12756,Q9H4A3 2 +Abnormality of taste sensation 0.3278746885012489 0.11867664689513 0.9055315388502296 1.0 1.0 3 Q12756,Q9H4A3 2 +Malabsorption 0.3822574234282558 0.1185960440042216 0.9055953996602856 1.0 1.0 43 Q08J23,Q9Y4P3,P09601,Q96A33,O76024,P40855,Q9NZ08,P01889,Q14566 9 +Color vision defect 0.3639527228845232 0.1172341886855579 0.9066744750553588 1.0 1.0 16 Q9Y4W6,Q9H061,Q8WWV3,Q13432,Q9Y6X9,Q6P4Q7,O60313 7 +Abnormal pulmonary thoracic imaging finding 0.3689464112543685 0.1146650944232268 0.908710582003847 1.0 1.0 19 P53992,P15260,P21964,Q9NZ08,P01889 5 +Increased susceptibility to fractures 0.3763227469415587 0.1145121995712546 0.9088317761544968 1.0 1.0 48 Q96AY3,O15269,Q13126,P48735,O75718,Q32P28,P40818,P16435 8 +Polyhydramnios 0.3812378010536686 0.1139108889085332 0.9093084336550236 1.0 1.0 43 P53992,Q70HW3,P21964,O75844 4 +Displacement of the urethral meatus 0.2583282669580949 0.1138243811676713 0.9093770108213926 1.0 1.0 103 Q02750,P07437,P51809,P53992,Q06124,Q08J23,O96028,Q969G3,P21964,P48449,Q9Y619,P40855,P37268,P16435,Q9UBX3,O75844 16 +Abnormal nephron morphology 0.3581191215922998 0.1134351582633927 0.9096855673233166 1.0 1.0 58 P00403,Q14C86,Q8N1F7,O75306,O95470,O43819,Q9Y4P3,P03886,P23786,Q8NFH4,Q9NZ08,P01889 12 +Abnormal vascular physiology 0.3807996680706089 0.111905596236171 0.910898259323383 1.0 1.0 43 P00403,Q9Y3Z3,Q9Y4P3,O96000,P49327,P03886,Q9NZ08,P01889,O75844 9 +Developmental regression 0.2593295537100628 0.111830179673128 0.9109580576904994 1.0 1.0 110 P13073,Q9NZJ7,O43819,P03886,O76024,P01889,Q92947,Q5JPH6,O95831,Q9NZ08,Q9Y3Z3,P42858,Q9Y4P3,O14936,P40855,P55795,Q15067,O75306,O95470 19 +Premature ovarian insufficiency 0.3660158680924 0.1111939966676863 0.9114625120778704 1.0 1.0 18 P49327,Q5JTZ9,Q9NR50,P40818 4 +Blindness 0.3292139489299949 0.1111021573433048 0.911535338022615 1.0 1.0 68 O43676,Q9NZJ7,O75306,Q969G3,O96000,P49327,P03886,Q96CU9,Q8NHS3,Q9NZ08,P01889,Q9Y6M9 12 +Spinal muscular atrophy 0.354905952625541 0.1104198110997119 0.9120764422125296 1.0 1.0 13 Q8TD16,Q16637,Q9Y6X9,Q99720,Q15813 5 +Multiple cafe au lait spots 0.3522020608298749 0.1098081331102761 0.9125615407651222 1.0 1.0 12 Q02750,O43684,Q15437,P21912,Q92889 5 +Asthma 0.3670542768142524 0.1085939257631639 0.9135245788006308 1.0 1.0 19 Q08J23,P21964 2 +Scleroderma 0.3262108262108229 0.1053509426411428 0.9160973414597964 1.0 1.0 4 Q14739,Q9Y2U8,P02545 3 +Esophageal neoplasm 0.332994540497167 0.1046333019065295 0.9166667886380336 1.0 1.0 6 O60216 1 +Joint contracture of the hand 0.3811431205911977 0.1043791772832413 0.9168684465299376 1.0 1.0 39 Q8IZA0,O43175,P42892,Q15042,P16435,Q9Y6X9,Q9Y619,Q15392,O75844 9 +Abnormal sacrum morphology 0.3768128599809748 0.1037964934779076 0.917330849238948 1.0 1.0 27 Q03164,P61978,Q08J23,O96028,Q9Y4P3,Q9UJX6,P01889 7 +Aplasia hypoplasia of the humerus 0.3384826256375901 0.1026632685658823 0.918230226994734 1.0 1.0 8 O00116 1 +Abnormality of the humerus 0.3466378190357025 0.1015092913424927 0.9191461822339048 1.0 1.0 11 P16435,O00116 2 +Abnormal circulating sex hormone concentration 0.3713293726353066 0.1014646761582358 0.9191815971503045 1.0 1.0 23 Q13423,P16435,Q969G3 3 +Preaxial foot polydactyly 0.3241167534298759 0.1001843942108603 0.9201979352929686 1.0 1.0 4 O95202,O96028 2 +Cachexia 0.359640888658248 0.0976478471115444 0.9222119295220794 1.0 1.0 17 Q99720,P35637 2 +Blepharitis 0.3496475686255503 0.0953250679580615 0.9240566319635304 1.0 1.0 13 P04080,Q92889,Q15800 3 +Postaxial polydactyly 0.3587879307225131 0.0950793193547245 0.9242518244129084 1.0 1.0 17 Q7Z4L5,O43924,P61978,Q9BW83 4 +Rieger anomaly 0.3219800012931236 0.0950033584144571 0.9243121593596246 1.0 1.0 4 O95202,O96028 2 +Radial deviation of the hand or of fingers of the hand 0.3441589935848138 0.0947044838402411 0.9245495563991392 1.0 1.0 11 Q06124,O43175 2 +Proximal muscle weakness 0.3648070427767098 0.0941402218306804 0.9249977698373032 1.0 1.0 53 P50402,P12235,Q8TB36,P35637,Q13126,P51114,Q9Y6X9,P36551,Q16637,Q9BUK6,Q99720,P22626,Q9BPX6,O60313 14 +Abnormality of the periorbital region 0.3474338592728239 0.0936879773578722 0.92535702094651 1.0 1.0 61 Q02750,P07437,Q14C86,Q08J23,Q9Y4P3,P38159,O75179,Q8NFH4,P40855,Q12769,Q8N1F7,P51812,P16435,Q7LGA3,Q6PGP7 15 +Abnormal umbilicus morphology 0.3628432430676894 0.0932123510816915 0.9257348623662864 1.0 1.0 54 P07437,P53992,O14936,P21964,O75844,Q9Y487 6 +Abnormal circulating creatinine concentration 0.3282252316464674 0.0925998352995755 0.926221474599194 1.0 1.0 6 Q10471,Q9UBS4,P00492,Q14697,Q16658 5 +Abnormal blood potassium concentration 0.348421390822336 0.0918871138228153 0.9267877298249636 1.0 1.0 13 Q13423 1 +Motor seizure 0.2534507377362475 0.0916460667886759 0.9269792494278376 1.0 1.0 94 O43175,Q96N66,Q9NZJ7,Q08J23,Q9NZ01,O14936,P03886,Q9Y619,Q8NHS3,Q9UBX3,Q92947,O43292 12 +Pulmonary artery stenosis 0.3454109402175865 0.090752906155524 0.9276889310047932 1.0 1.0 12 Q9Y4P3,Q06124 2 +Upper limb muscle weakness 0.3680784245934427 0.0907277612384666 0.9277089113193024 1.0 1.0 23 P46976,P50402,P36551,Q969G3 4 +Abnormal glomerular mesangium morphology 0.3572875414906565 0.0905983853967106 0.9278117149243084 1.0 1.0 17 Q9BW27,Q14C86,O95470,Q8NFH4,Q12769,Q8N1F7 6 +Abnormality of lower limb epiphysis morphology 0.3447539864983343 0.0889599452805112 0.9291137428966476 1.0 1.0 12 O95831 1 +Abnormal eating behavior 0.3581102870428343 0.0868760275805495 0.9307700546802582 1.0 1.0 18 Q4J6C6,P53007,P42858,Q969G3,Q9UJS0,Q6IA86 6 +Postaxial hand polydactyly 0.3437515992409572 0.0862415062246945 0.9312744364015916 1.0 1.0 12 Q7Z4L5,O43924,Q9BW83 3 +Distal muscle weakness 0.3575429102751689 0.0854485585230439 0.931904790174463 1.0 1.0 56 O15269,Q9Y4W6,P04792,Q8TB36,P35637,O95831,Q96BR5,P36551,Q9Y6X9,Q99720,P22626,P46976 12 +Intestinal malrotation 0.3701319848214704 0.0843635968113544 0.9327673496073576 1.0 1.0 26 P53992,Q9Y2U8,O96028,O95202,Q14739,Q9NSD9,P21964,O75312,Q15392,P49454,O60216 11 +Spina bifida occulta 0.352940885916973 0.0842845686514409 0.9328301811749083 1.0 1.0 16 Q08J23,Q06124 2 +Spastic paraplegia 0.3760451022269511 0.0840817851911145 0.9329914066664736 1.0 1.0 40 Q7KZN9,O75306,P54886,P48643,O95831,Q9Y619,Q15041,P40818,Q96CU9,O60313 10 +Cavum septum pellucidum 0.3396955135034234 0.0827706552835974 0.9340339027307292 1.0 1.0 11 Q9BVA1,O96028 2 +Abnormal reflex 0.2567169874683061 0.0824014221910243 0.9343275051529027 1.0 1.0 303 P50402,P13073,P12235,Q9NZJ7,Q08J23,O43819,P48643,P49327,P03886,P49589,Q96BR5,Q9Y619,Q15041,Q86XL3,P01889,Q96AY3,O15269,Q9NXN4,P61978,Q9Y4W6,Q15042,P54886,O14979,O95831,P40818,Q9NZ08,P04792,O60313,O43292,Q7KZN9,Q9BVA1,Q96N66,Q9HC21,P42858,Q9Y4P3,Q9Y263,O14936,P51114,Q16637,P40855,Q99720,P51812,Q9BQP7,O14949,Q15067,Q9BT22,O75306,Q8TB36,Q13217,P35637,Q5JRX3,Q3ZCQ8,O75648,Q15120,Q96CU9,Q9BUK6,Q6DKK2,Q9Y320 58 +Arachnodactyly 0.3725655278021695 0.0821939516648326 0.9344924830450718 1.0 1.0 29 P53992,Q9Y285,Q969G3,P21964,P16435,P55795 6 +Diastema 0.3272727272727236 0.0821798264156485 0.9345037153637948 1.0 1.0 7 Q8WVM7,Q8TC12,O15347,Q8WXI9,Q9BSJ2,Q99496 6 +Clonus 0.3693227983423682 0.0816353683315008 0.934936675286648 1.0 1.0 26 Q9NZJ7,P42858,P35637,P48643,Q3ZCQ8,P40818,Q9Y619,Q99720 8 +Abnormality of the pituitary gland 0.3501716484762177 0.0807740576672131 0.9356216396216924 1.0 1.0 59 Q03164,O14654,Q15233,O76024,Q9NSE4,P57740,P42356,Q969G3,P40818,Q96IJ6,Q15813,O75874,Q9UHX1,P51809,Q9Y285,Q9UBS4,P16435,P48735,Q9BUK6,Q9NRG9,Q9UM00 21 +Distal sensory impairment 0.3753697222409696 0.0801941356651845 0.93608285420293 1.0 1.0 39 O15269,Q8TB36,P48643,Q15120,O95831,Q96BR5,Q9Y6X9,Q9BUK6,P04792 9 +Tachycardia 0.365680624446392 0.0782353319352355 0.937640857317466 1.0 1.0 24 O43772,P23786 2 +Functional abnormality of male internal genitalia 0.3696772229799058 0.0753939971068656 0.9399012352325248 1.0 1.0 28 Q9Y4P3,Q9UBS4,O76024,Q13423,P16435,P51809 6 +Generalized hirsutism 0.3647683206551074 0.075294462094041 0.9399804275854692 1.0 1.0 24 P07437,Q03164,Q06136,P40818 4 +Abnormal cranial nerve physiology 0.3492144123290142 0.0752600950067165 0.9400077709710336 1.0 1.0 59 Q9BQP7,P12235,Q06124,O75874,Q9NZJ7,P51812,O43819,Q9BUF5,Q969G3,P48735,P40855,Q9NZ08,P01889 13 +Abnormal toenail morphology 0.3730602135590478 0.074879625410823 0.9403104876054054 1.0 1.0 42 Q08J23,P04080,Q969G3,P23786,O75844 5 +Neoplasm of the adrenal gland 0.342075986536698 0.0745978207557725 0.9405347080787994 1.0 1.0 13 P48735,O96017,O75874,P21912 4 +Increased circulating gonadotropin level 0.3331091887628876 0.0733410366375707 0.9415347370941164 1.0 1.0 10 P16435 1 +Abnormal tongue physiology 0.3512129599975897 0.0729466688304374 0.9418485564823764 1.0 1.0 17 P51114,O95831 2 +Skin ulcer 0.3667060845967211 0.0729144868483355 0.941874165792104 1.0 1.0 26 O15269,O75874,P48643,P48735,P01889 5 +Dental malocclusion 0.3570197033022171 0.0719088431225227 0.9426744524768988 1.0 1.0 20 P51812,Q9Y4P3,Q06124,P61978 4 +Hyperextensible skin 0.3382983399934237 0.0718206320528887 0.9427446532158938 1.0 1.0 12 Q02750,P54886,Q06124 3 +Hammertoe 0.3506622244044797 0.0713855572920522 0.9430909038948 1.0 1.0 17 Q99720,Q8TB36,Q96BR5 3 +Abnormal patella morphology 0.3634821237093522 0.0711801356267877 0.943254390783199 1.0 1.0 24 Q96AY3,P53992,Q9Y4P3,P21964,Q9Y619 5 +Restrictive ventilatory defect 0.3320955934224975 0.0708147106671822 0.9435452237991164 1.0 1.0 10 P01889 1 +Glioblastoma multiforme 0.3220617548625692 0.0697725359441534 0.944374707030662 1.0 1.0 7 O75874 1 +Stenosis of the external auditory canal 0.3219250817935201 0.069454659516259 0.94462772191855 1.0 1.0 7 P16435 1 +Vascular dilatation 0.3353682984958419 0.069353397654657 0.9447083228364744 1.0 1.0 64 Q06124,P61978,Q9Y3Z3,P54886,Q9Y4P3,P42858,Q9UGP8,Q9UJX6,P49589,O75648,Q96PU5,P38435,P01889,Q7LGA3,O75844 15 +Papillary thyroid carcinoma 0.3215686274509715 0.0686274308300721 0.9452861836915272 1.0 1.0 7 Q96GM5,Q12824,O14497,P51532,Q15437,Q969G3 6 +Abnormal shape of the palpebral fissure 0.3337065055431588 0.0674104944667146 0.946254914818024 1.0 1.0 11 O75179,Q92889,P55795 3 +Low hanging columella 0.3305773699531019 0.0670709062086765 0.9465252552069368 1.0 1.0 10 P55795 1 +Absent hair 0.3333519150791357 0.0665247094030039 0.9469600860209644 1.0 1.0 11 O75844 1 +Stage 5 chronic kidney disease 0.3668534074931325 0.0658046342387845 0.9475333666468148 1.0 1.0 28 Q14C86,O95470,Q9UBS4,Q7Z4L5,Q8NFH4,P23786,Q8N1F7 7 +Abnormal aortic arch morphology 0.3329751879816759 0.065586534961805 0.9477070095740884 1.0 1.0 11 P21964 1 +Increased laxity of ankles 0.3003558718861298 0.0646100073362283 0.9484845166583904 1.0 1.0 2 O95140 1 +Neoplasm of the ear 0.308427431286171 0.0642995264765681 0.9487317304933628 1.0 1.0 4 Q9UJX6 1 +Impaired social interactions 0.3698603497465045 0.0634353087358407 0.9494198715524294 1.0 1.0 43 P03886,Q9Y6M9,O43676,Q96CU9 4 +Nail dysplasia 0.3609577432038404 0.0632140124670635 0.9495960867612498 1.0 1.0 24 P16615,O96028,Q9Y619,P51812,P10321 5 +Abnormality of the thoracic cavity 0.3278419809372734 0.060447975005465 0.951798849957694 1.0 1.0 10 P01889,Q969G3,Q92990 3 +Abnormal labia morphology 0.3458452618762136 0.0580128150113987 0.9537384208162012 1.0 1.0 17 P51809,Q15042,Q9Y619,P16435 4 +Incomplete penetrance 0.3664570802496819 0.0551264034566752 0.9560377612065988 1.0 1.0 31 Q14671,P50995,Q92733,Q969G3,P21912,O14979,P03886,P36551,O60313 9 +Diffuse cerebral atrophy 0.3372461976970886 0.0550899375139057 0.956066812672469 1.0 1.0 14 Q9NZJ7,O00429,Q10713,O14936,Q9H269,Q14746 6 +Tremor by anatomical site 0.3582971844433912 0.0549757540150168 0.9561577800663624 1.0 1.0 24 Q9Y4W6,P35637,Q15120,Q16637,Q99720 5 +Disproportionate tall stature 0.3565017558004957 0.0543936522720154 0.9566215361227846 1.0 1.0 23 O75648,P16435,P42858,Q7LGA3 4 +Abnormal shoulder morphology 0.3632208244669714 0.0537440064681892 0.9571391213531024 1.0 1.0 28 P42858,Q9Y4P3,O75648,Q9Y619,Q7LGA3 5 +Fever 0.2996905965977293 0.0535737142799383 0.9572747993930232 1.0 1.0 74 P00403,P61978,Q9NZJ7,Q14C86,P15260,Q9Y3Z3,Q8N1F7,O14936,P03886,P23786,Q8NFH4,Q9NZ08,P01889 13 +Long clavicles 0.2983416880874162 0.0521458724685391 0.9584124617183184 1.0 1.0 3 Q15813 1 +Speech apraxia 0.356675339998761 0.0500338484654187 0.9600954149159904 1.0 1.0 24 O75648,P42858,Q9Y619 3 +Thyroid carcinoma 0.3321435526239217 0.0492506008934648 0.9607195864822362 1.0 1.0 13 P49327,O96017,Q969G3,P21912 4 +Spinal canal stenosis 0.3086936660253194 0.0481692789391695 0.9615813336105354 1.0 1.0 6 Q15813 1 +Abnormal head movements 0.3257160952663245 0.0480968943460437 0.9616390212958554 1.0 1.0 11 Q99720 1 +Megalocornea 0.3191438244355073 0.0478120879196487 0.9618660028083128 1.0 1.0 9 Q9Y4P3,Q96EK5,O96028 3 +Abnormal carotid artery morphology 0.3341573757139168 0.0473264057683016 0.9622530828978376 1.0 1.0 14 Q9Y4P3,O75844 2 +Large hands 0.3251157879165701 0.046700786165917 0.9627517037613764 1.0 1.0 11 P51812,Q9UJX6,O43175 3 +Abnormal nasal base 0.3219129193433346 0.0466351471971581 0.9628040190813528 1.0 1.0 10 Q96GM5,Q12824,O14497,P51532,Q96ST3,Q13868,Q93008,Q969G3,P21281 9 +Myalgia 0.3661020805435745 0.044468832220025 0.9645306956756016 1.0 1.0 36 P12235,P53992,P21964,P23786,Q9BUK6,Q9NZ08,P01889,O60313 8 +Abnormal thyroid morphology 0.3646484779084074 0.0440226720469792 0.9648863317040036 1.0 1.0 33 P12235,P50851,O14654,O75874,Q15437,P42892,Q969G3,P21912,P49327,P48735,Q96J02,O96017 12 +Ankyloblepharon 0.2975506210475719 0.0423752970406038 0.9661995207618934 1.0 1.0 4 P18074,Q92889 2 +Abnormality of the metaphysis 0.3657979088407899 0.0423387685083527 0.9662286401802442 1.0 1.0 40 Q13126,P48735,Q7Z4L5,O95831,Q96HY6 5 +Atrial arrhythmia 0.3199463369735583 0.0422182974620921 0.9663246762986056 1.0 1.0 10 P50402 1 +Sideroblastic anemia 0.312777190973202 0.0414810632880773 0.9669123891661332 1.0 1.0 8 O76024,Q92889 2 +Increased blood pressure 0.3221007502630471 0.0410405044861695 0.9672636051379668 1.0 1.0 67 P00403,P53992,P42892,Q9Y4P3,Q9UBS4,Q9BW83,P03886,P21964,P36551,P40818,P35611,Q96J02,P01889,P16435,O75844 15 +Delayed ability to walk 0.3452006510348538 0.0405353775604544 0.9676663029942244 1.0 1.0 58 P61978,Q96N66,Q01105,P35637,O14936,Q3ZCQ8,O75648,P48449,Q99720 9 +Areflexia 0.2941154760516867 0.0405075520243035 0.96768848634003 1.0 1.0 75 P12235,O15269,Q15067,P61978,Q9BT22,Q13217,Q8TB36,O43819,P54886,P51114,Q15120,O95831,Q9Y6X9,Q16637,Q15041,P04792,O60313 17 +Prominent nose 0.3307116892807046 0.0389109330433231 0.9689613998633602 1.0 1.0 14 Q08J23,Q9UJX6,P40855 3 +Morphological abnormality of the corticospinal tract 0.3277764560740485 0.0387781230512499 0.9690672869889332 1.0 1.0 13 P35637 1 +Abnormal mitral valve physiology 0.3623953045764594 0.0385898529208097 0.9692173924642832 1.0 1.0 32 O75306,P51812,O43819,Q9Y4P3,P49327,Q9NZ08,P01889,O75844 8 +Abnormality of the peripheral nervous system 0.2491391756781145 0.0382685820777132 0.9694735402987072 1.0 1.0 95 O15269,P53992,Q9NZJ7,Q15120,P21964,O95831,Q9Y619,Q99720,P04792,O60313 10 +Chronic kidney disease 0.3635239322391799 0.0380819113212017 0.9696223735225336 1.0 1.0 34 O95470,Q7Z4L5,P23786,Q92947 4 +Short columella 0.2861209964412886 0.037812740710064 0.9698369860201436 1.0 1.0 2 P49454 1 +Renal tubular dysfunction 0.3590266500426251 0.0365769488468684 0.9708223233840272 1.0 1.0 29 P00403,O43676,O43819,O96000,P03886,P40855,Q96CU9,Q9Y6M9 8 +Excessive daytime somnolence 0.3267582352015206 0.0363958597869467 0.9709667154053824 1.0 1.0 13 P42858 1 +Poor motor coordination 0.3172497574948133 0.0362956035132881 0.9710466555198496 1.0 1.0 10 Q92947 1 +Long philtrum 0.2531001996213364 0.0354236785036594 0.9717419038427396 1.0 1.0 109 Q13555,P07437,Q03164,P53992,P42858,Q9Y4P3,Q9Y263,O14936,O75648,P21964,O75718,P51812,P16435,Q7LGA3,Q9Y487 15 +Abnormal neuron morphology 0.3574971696882629 0.0353804794124365 0.9717763501380046 1.0 1.0 28 P50995,P54886,P35637,Q16637,Q15165,Q99720,P22626,Q92804 8 +Profound global developmental delay 0.3199736260410495 0.035057753307735 0.9720336886641237 1.0 1.0 11 P37268,O60313,P40855 3 +Pituitary growth hormone cell adenoma 0.2927350427350434 0.0334414988811031 0.9733225168340456 1.0 1.0 4 P10644,Q9UBS4,Q14697 3 +Pseudobulbar paralysis 0.3081497417538502 0.0319313258754352 0.9745268169351144 1.0 1.0 8 Q15233,P54886 2 +Adducted thumb 0.3484413225524405 0.0309012940684401 0.975348257899952 1.0 1.0 23 Q86XL3,P54886,Q9Y4P3,O43175 4 +Abnormal social behavior 0.3411010564022158 0.0297965277173074 0.9762293280189512 1.0 1.0 59 Q15067,O43676,Q9NZJ7,Q9Y4P3,O96000,P03886,Q96CU9,Q9Y6M9 8 +Abnormal cerebral artery morphology 0.3267266597138766 0.029501976424825 0.9764642426698747 1.0 1.0 14 P38435,Q9Y3Z3,Q9UBS4 3 +Gastrostomy tube feeding in infancy 0.355581072595029 0.0294104620840515 0.9765372288786452 1.0 1.0 28 P37268,P35637,Q7L7X3,Q96J02,Q99720 5 +Congenital malformation of the great arteries 0.2482930716995937 0.0288932448049632 0.9769497332389638 1.0 1.0 95 Q02750,P53992,Q06124,O43175,Q6PGP7,P42892,Q9UM00,Q9Y4P3,Q969G3,Q9UJX6,P21964,Q96PU5,P40855,P01889,Q15392,Q92889,O75844 17 +Dysmetric saccades 0.2942351217842043 0.0281878398786478 0.9775123357429902 1.0 1.0 5 O95140,Q9Y4W6 2 +Broad long bones 0.3569453528242077 0.0265178706233178 0.978844279914787 1.0 1.0 30 O14936,O75648,Q08J23,P42858 4 +Poor suck 0.3428323167885018 0.0261891307826947 0.9791064852894158 1.0 1.0 21 O75306,Q15233,O43819,Q9Y263,O75648,P22695 6 +Central adrenal insufficiency 0.2928393302458096 0.0256878610822122 0.9795063061165789 1.0 1.0 5 Q9NRG9,Q9NSE4,P35222,Q9NW13 4 +Abnormality of the lens 0.2578495085965428 0.0250960635053771 0.9799783400624827 1.0 1.0 183 P12235,Q06136,Q08J23,P36404,P49327,P03886,P21964,P23786,O76024,P08670,P01889,P22626,O15228,P00403,P53992,Q15042,Q9Y287,O14979,P40818,Q9NZ08,O60313,Q7LGA3,Q9BVA1,Q9Y4P3,O14936,P48449,P40855,P51812,Q9UJS0,Q9NVI7,O43175,Q15800,Q13126 33 +Broad thumb 0.3497977623326329 0.0249798756681327 0.9800710154902588 1.0 1.0 25 O75648,Q08J23,P42858 3 +Dysphasia 0.3323593224227285 0.0233020618644678 0.9814093270314864 1.0 1.0 17 P21964 1 +Peptic ulcer 0.3107585746210583 0.0226731960941038 0.9819109567563328 1.0 1.0 10 O76024 1 +Clinodactyly 0.2532125173586141 0.0214920754272909 0.982853124897312 1.0 1.0 119 Q03164,Q06124,O43175,Q08J23,P42858,O43924,Q969G3,Q9Y4P3,O75648,Q8NFH4,Q9Y619,Q96J02,P51812,P16435,Q7LGA3 15 +Abnormal left ventricle morphology 0.3512927317374144 0.020465055925999 0.9836723875663624 1.0 1.0 27 O75880,P00403,P12235,Q07021,Q06124,P13807,P03886 7 +Abnormality of bone mineral density 0.2528970347615501 0.0197095260258849 0.9842750915869768 1.0 1.0 118 P12235,Q9NZJ7,O96028,Q15392,Q9Y487,O15228,Q96AY3,P61978,Q15042,P54886,O75718,O95831,Q96HY6,P40818,O43292,Q9HC21,Q9Y4P3,P51809,O75844,Q02750,O43175,Q13126,Q32P28 23 +Aplasia hypoplasia of the optic nerve 0.3355409017467154 0.0188904226287212 0.9849285198142615 1.0 1.0 19 Q9NVI7,P61978,Q9UHX1,O14936,O75312,P37268,P49454 7 +Leukodystrophy 0.3523468089573335 0.0177915785223969 0.9858051230636392 1.0 1.0 51 Q7KZN9,Q15067,O43676,Q9NZJ7,Q9Y3Z3,O43819,O96000,P03886,Q96CU9,Q9Y6M9 10 +Neoplasm of the nervous system 0.3587855831019639 0.0176769998701862 0.9858965292262072 1.0 1.0 43 P07437,Q06124,O43924,Q969G3,P48735,Q92947 6 +Aplasia hypoplasia of the hallux 0.3322683872565654 0.0168851498530575 0.9865282397801876 1.0 1.0 18 O75648,P42858,Q7LGA3 3 +Upper limb amyotrophy 0.3210198492497732 0.0166348612695665 0.9867279131303086 1.0 1.0 14 P31483,Q8TB36,Q15120,Q9Y6X9,P04792 5 +Attention deficit hyperactivity disorder 0.2439566545598946 0.0154149994717597 0.98770109700071 1.0 1.0 89 Q9BVA1,P53992,Q08J23,P42858,O75648,P21964,O75179,P51812,Q7LGA3,P55795 10 +Aganglionic megacolon 0.331560628800792 0.0151791361591169 0.9878892666787245 1.0 1.0 18 P53992,Q96EK5,P42892,Q9BYW2,Q9UJX6,Q10713,P21964,Q92889 8 +Abnormality of coagulation 0.3538982693111072 0.0145866862418863 0.9883619209642118 1.0 1.0 49 P47985,Q06124,O75874,P48735,O75648,Q4KMQ2,Q9Y619,P40855,Q9UJS0,Q9Y487 10 +Abnormal renal pelvis morphology 0.3555824083596309 0.0140529297629192 0.9887877533507808 1.0 1.0 47 Q02750,P61978,Q5JRA6,Q08J23,Q15042,Q9UJX6,O76024,O75718,P23786,P40855,P16435,O43505 12 +Insomnia 0.319619642691048 0.0135872372573932 0.989159286725516 1.0 1.0 14 Q9UJS0,P42858,Q9Y4P3 3 +Chorioretinal dysplasia 0.2744749021003976 0.0112917189160929 0.9909907032642647 1.0 1.0 3 Q01968,O43505 2 +Respiratory distress 0.3567750916259026 0.0112894005190316 0.9909925529595855 1.0 1.0 44 Q9NZJ7,Q00325,P03886,O75648,P23786,O95831,Q9Y619 7 +Down sloping shoulders 0.3388874153288891 0.010346191437816 0.9917450808617352 1.0 1.0 22 O75648,P42858,Q7LGA3 3 +Macular thickening 0.2882656166151626 0.0101174512884541 0.99192757954179 1.0 1.0 6 P04439 1 +Sleep disturbance 0.2533273921127066 0.0100176186770516 0.9920072304044404 1.0 1.0 133 Q01105,Q08J23,Q7L7X3,O76024,P49589,P61978,Q9NZ01,Q969G3,O95831,P40818,Q7LGA3,Q96N66,P42858,Q9Y4P3,Q96A33,O14936,P51114,Q8NHS3,Q9UJS0,P51812,Q9NVI7,O75648 22 +Frontal cortical atrophy 0.3237182643194755 0.0095269895180957 0.9923986771399028 1.0 1.0 16 O75648,P42858 2 +Colorectal polyposis 0.2919307277110415 0.009081916897941 0.9927537783376356 1.0 1.0 7 O96017,P21912 2 +Large intestinal polyposis 0.2919307277110415 0.009081916897941 0.9927537783376356 1.0 1.0 7 O96017,P21912 2 +Epileptic spasm 0.3446535741606458 0.0087339110617396 0.9930314358036012 1.0 1.0 55 O43175,Q96N66,Q08J23,Q9NZ01,O14936,P03886,Q9UBX3,Q92947 8 +Pectus carinatum 0.3532655579595275 0.0086187776666022 0.9931232955043474 1.0 1.0 32 Q96AY3,Q02750,Q06124,Q9Y263,Q9Y619,P51812,P55795 7 +Broad based gait 0.3311806275347963 0.0082382276773971 0.9934269196786456 1.0 1.0 19 Q03164,P42858 2 +Emg neuropathic changes 0.340041975003511 0.0080444736508993 0.9935815079014784 1.0 1.0 23 Q9NZJ7,Q8TB36,O43819,P22626,Q16637,P04792,O60313 7 +Joint hyperflexibility 0.3539285535004887 0.0055270511754207 0.9955900736529976 1.0 1.0 34 P53992,Q06124,Q08J23,P21964,Q9Y619 5 +Tetraparesis 0.3521624149571178 0.0051430761919629 0.9958964370021246 1.0 1.0 32 Q5JPH6,Q9NZJ7,P35637,Q8NCW5,Q9UBX3,Q15813 6 +Regional abnormality of skin 0.2518271131568855 0.0034353796687349 0.9972589689933532 1.0 1.0 119 Q96AY3,P16615,Q06124,O43175,P61978,P42166,Q06136,P42858,Q9Y4P3,Q9Y263,O75648,P42167,Q96J02,P40855,P51812,Q7LGA3,P55795,Q9Y487 18 +Phimosis 0.2731481481481453 0.0019087164934659 0.9984770655036392 1.0 1.0 4 Q9BYW2,Q9UJX6,P49711 3 +Aortic root aneurysm 0.3375584296625573 0.0016078961335077 0.9987170850524928 1.0 1.0 23 P49589,P42858,Q7LGA3,O75648 4 +Left ventricular hypertrophy 0.3375575884073105 0.0016057408931345 0.9987188046832912 1.0 1.0 23 O75880,P00403,P12235,Q07021,Q15233,P13807,P03886 7 +Postural tremor 0.3164591650556611 0.0003115262522589 0.9997514380170582 1.0 1.0 15 O75306,P03886,P35637 3 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..120249b3818918ae27a0990df20b840a217a8fdd --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar ridge overgrowth", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of the ears", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 5th toe", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatological manifestations of systemic disorders", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the 5th toe", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgenesis of the cerebellar vermis", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged epiphyses", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hypertrichosis", "Facial hypotonia", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Helicobacter pylori infection", "Hemangioblastoma", "Hemangiomatosis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic ilia", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens subluxation", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip movement", "Limited wrist movement", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuchal rigidity", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Photosensitive tonic clonic seizure", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent infection of the gastrointestinal tract", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Reflex seizure", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowed slurred speech", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced primary teeth", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zonular cataract"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APPL1", "APRT", "ARCN1", "ARHGDIA", "ARHGEF2", "ARID1A", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP5A1", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATXN10", "B3GALT6", "B4GAT1", "BANF1", "BAZ1B", "BCAP31", "BCOR", "BCS1L", "BICD2", "BLVRA", "BMS1", "BPTF", "BUB1B", "BUB3", "C19orf70", "C1QBP", "CACNA2D1", "CAD", "CALD1", "CALR", "CAMK2G", "CAPN1", "CARS", "CASK", "CAST", "CBFB", "CCDC22", "CCDC47", "CCDC8", "CCT5", "CD2AP", "CDC42", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CENPF", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHEK2", "CHMP2B", "CHMP4B", "CHORDC1", "CISD2", "CKAP2L", "CLASP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNP", "COA3", "COA7", "COG2", "COG4", "COG7", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT2", "CRKL", "CRTAP", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL3", "CUL4B", "CWF19L1", "CYB5R3", "CYC1", "DARS", "DARS2", "DBR1", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DHCR24", "DHCR7", "DHFR", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DIP2B", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJB11", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPM1", "DSG2", "DSP", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FAH", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FIP1L1", "FKBP10", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GCDH", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GNAI2", "GNAI3", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GRHPR", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HCFC1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGA2", "HMGB3", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP2", "IGF2R", "IMPAD1", "INTS1", "IQSEC1", "IRF2BPL", "IRS4", "ITCH", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KMT2A", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRSAM1", "LSS", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MANBA", "MAP1B", "MAP2K1", "MAPK1", "MAPRE2", "MARS", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MFF", "MFN2", "MFSD8", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMADHC", "MOGS", "MORC2", "MPDU1", "MPG", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFS", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MYH9", "MYO6", "NAA15", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPH", "NCDN", "NCSTN", "ND1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NEDD4L", "NEK9", "NF1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOVA2", "NPC1", "NPC2", "NPM1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NT5C2", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OSGEP", "OXCT1", "P3H1", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PAPSS2", "PARK7", "PARN", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDK3", "PEPD", "PEX14", "PEX19", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PITRM1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCSH", "PRKDC", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PTCD3", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RBPJ", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RTN4IP1", "SALL2", "SAMHD1", "SARS", "SARS2", "SBDS", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIL1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC9A3R1", "SLC9A6", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SNAP29", "SNRNP200", "SNRPE", "SON", "SORD", "SPART", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SRP54", "SRP72", "SSBP1", "STAG1", "STAG2", "STARD7", "STAT1", "STAT3", "STT3A", "STT3B", "STUB1", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAF2", "TALDO1", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D8B", "TBCD", "TBCE", "TBK1", "TBL2", "TCF20", "TCOF1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM50", "TKT", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOMM40", "TOP2A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TPRKB", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXNL4A", "TXNRD2", "UBA1", "UBE3A", "UBE4A", "UBR1", "UBTF", "UFD1", "UFM1", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VAPB", "VARS1", "VCL", "VCP", "VIM", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VRK1", "WARS", "WARS2", "WBP11", "WDR1", "WDR11", "WDR36", "WFS1", "WNK1", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YEATS2", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZFR", "ZMPSTE24", "ZNF687", "ZPR1"], "leading_proteins": ["AAAS", "AARS2", "ABHD12", "ACAT2", "ACOX1", "ACSF3", "ADAR", "ADD1", "ADK", "AFG3L2", "AGK", "AGPS", "AIFM1", "AKT2", "ALDH18A1", "ALDH3A2", "ALG1", "ANAPC1", "ANAPC2", "ANKLE2", "ANKRD17", "ANO6", "ANXA11", "APOL2", "APPL1", "ARID1A", "ARL2", "ARL6IP1", "ATAD1", "ATAD3A", "ATIC", "ATP1A1", "ATP2A2", "ATP6V0A2", "ATP6V1B2", "B3GALT6", "B4GAT1", "BICD2", "BUB1B", "BUB3", "C19orf70", "C1QBP", "CAMK2G", "CARS", "CASK", "CCDC47", "CCT5", "CDK4", "CENPF", "CEP55", "CHEK2", "CLPP", "CNNM4", "COA3", "COA7", "COG2", "COMT", "COX15", "COX2", "COX4I1", "CPNE1", "CPOX", "CPT2", "CRTAP", "CSTB", "CTCF", "CTNNB1", "CTPS1", "CWF19L1", "DCTN1", "DDB1", "DDRGK1", "DHCR24", "DHCR7", "DHFR", "DIABLO", "DNAJB11", "DNAJC3", "DNM1L", "DNM2", "DOCK7", "DPM1", "DYNLL1", "EARS2", "ECE1", "EFL1", "EIF2B3", "ELP2", "EMD", "ERAP1", "ERCC2", "ERCC3", "ERCC4", "ERLIN1", "EWSR1", "EXOSC2", "EXOSC8", "FARSA", "FARSB", "FASN", "FDFT1", "FDPS", "FH", "FKBP10", "FOXRED1", "FSCN1", "FUS", "FXR1", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GATAD2B", "GBA", "GCDH", "GDAP1", "GDAP2", "GGCX", "GLDC", "GLMN", "GLRX5", "GMPPA", "GNPAT", "GPAA1", "GPHN", "GSDME", "GSTM3", "GUSB", "GYG1", "GYS1", "HADHA", "HLA-A", "HLA-B", "HLA-C", "HMGB3", "HMOX1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HPRT1", "HS2ST1", "HSD17B4", "HSPB1", "HTT", "IARS2", "IDH1", "IDH2", "IFNGR1", "IFT27", "IGF2BP2", "IRS4", "ITCH", "ITM2B", "JAGN1", "KDSR", "KIAA0319L", "KIF14", "KIF1A", "KIF1B", "KIF20A", "KIFBP", "KMT2A", "LAS1L", "LBR", "LEMD3", "LETM1", "LMAN1", "LMNA", "LMNB2", "LRBA", "LSS", "MAP2K1", "MAPRE2", "MATR3", "MBOAT7", "MCM2", "MCM6", "MFN2", "MFSD8", "MGME1", "MIA3", "MICU1", "MID1", "MMADHC", "MOGS", "MORC2", "MPG", "MRE11", "MSH2", "MSMO1", "MSTO1", "MTAP", "MTCH1", "MTOR", "MTX2", "MYH9", "NAGLU", "NAXE", "NCDN", "ND1", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS6", "NEDD4L", "NNT", "NONO", "NPC1", "NSD2", "NSUN2", "NUP107", "NUP133", "NUP155", "NUP160", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "OCRL", "OPA1", "P3H1", "P4HB", "PALLD", "PAPSS2", "PCBD1", "PDE6D", "PDK3", "PEX19", "PGM3", "PHGDH", "PHIP", "PI4KA", "PIGK", "PIGT", "PITRM1", "PLAA", "PLEC", "PMPCA", "POLR1C", "PON2", "POR", "PPP1R12A", "PPP2R1B", "PRCC", "PREPL", "PRKAR1A", "PSAP", "PSMB4", "PTPN1", "PTPN11", "PTRH2", "PUF60", "PUM1", "PUS7", "RAB23", "RAB3GAP1", "RAD21", "RAPGEF2", "RBM10", "RBM28", "RBM8A", "RBMX", "RDH11", "RNF2", "RPL10", "RPS6KA3", "RTN4IP1", "SALL2", "SAMHD1", "SCO1", "SCO2", "SDHB", "SEC23B", "SEC24C", "SEC61A1", "SEC63", "SET", "SETD2", "SFXN4", "SGPL1", "SIGMAR1", "SIN3A", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SMARCA4", "SMARCB1", "SMARCD1", "SMARCE1", "SMN1*", "SPECC1L", "SPEN", "SPTLC1", "SQSTM1", "STAG1", "STAT1", "STT3A", "TAF15", "TAOK1", "TBCE", "TBL2", "TECR", "TELO2", "TIA1", "TIMM50", "TMCO1", "TMEM126A", "TMEM199", "TMPO", "TMX2", "TP53", "TRIP13", "TRMU", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TWNK", "UBE3A", "UNC119", "UNG", "UQCRC2", "UQCRFS1", "UQCRQ", "USP8", "USP9X", "VAMP7", "VCP", "VIM", "VPS16", "VPS33A", "WFS1", "WNK1", "YIPF5", "ZMPSTE24", "ZPR1"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5f1e8929ffc3ce1f9126f42fee0a5ea7a0ffcfbb --- /dev/null +++ b/msigdb_kegg/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Steroid biosynthesis"} \ No newline at end of file diff --git a/msigdb_kegg/advanced/plot_0.png b/msigdb_kegg/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..fdb36898f23f89c3954f589914db36bfa47c1b77 --- /dev/null +++ b/msigdb_kegg/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2b1cba628184d1f5bdad041112cef5abd8877d718a980034e5912ea6a6d25d6 +size 186079 diff --git a/msigdb_kegg/basic/idx2term.json b/msigdb_kegg/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ebb7e144bcc3f45dd40b401cf6d6b2aa6208f5f2 --- /dev/null +++ b/msigdb_kegg/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Steroid biosynthesis", "1": "Huntingtons disease", "2": "Oxidative phosphorylation", "3": "Calcium signaling pathway", "4": "Parkinsons disease", "5": "P53 signaling pathway", "6": "Glycerophospholipid metabolism", "7": "Natural killer cell mediated cytotoxicity", "8": "Neurotrophin signaling pathway", "9": "Porphyrin and chlorophyll metabolism", "10": "Glioma", "11": "Cardiac muscle contraction", "12": "Progesterone mediated oocyte maturation", "13": "Alzheimers disease", "14": "Peroxisome", "15": "Fatty acid metabolism", "16": "Oocyte meiosis", "17": "Proteasome", "18": "Drug metabolism cytochrome p450", "19": "Valine leucine and isoleucine biosynthesis"} \ No newline at end of file diff --git a/msigdb_kegg/basic/plot_0.png b/msigdb_kegg/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..370466ed5342f008236808e7bffed9a52f5c6583 --- /dev/null +++ b/msigdb_kegg/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:96292d281911bf446cd01d082a497071278c21111695dcc79bbcbad885b15514 +size 135966 diff --git a/msigdb_kegg/basic/plot_1.png b/msigdb_kegg/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..66e84080af3fe7329f75d92bbce13db8f8f3bb89 --- /dev/null +++ b/msigdb_kegg/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f7db0ceac23326b6276f729a79e2ca552aff359a09e9df3ad4736c561b7e5226 +size 141435 diff --git a/msigdb_kegg/basic/plot_10.png b/msigdb_kegg/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..2f64ceaef99c50bb880745fb3dc80a4ad679fe36 --- /dev/null +++ b/msigdb_kegg/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24f747d2e503a9a74ea85c9d8a093c651a4c845caa98f1652dad2f4322e2ff11 +size 130312 diff --git a/msigdb_kegg/basic/plot_11.png b/msigdb_kegg/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..d43bee3139b8e1fc35d45a3dea81a68e487d642b --- /dev/null +++ b/msigdb_kegg/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8bd581bcfda4a7a12c0061499433c8ae3bfbf6e7b4763636d0e9082caf2fb49 +size 141461 diff --git a/msigdb_kegg/basic/plot_12.png b/msigdb_kegg/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..d4956d50f5d4db38b0a9de2c92f3fcb01d700e36 --- /dev/null +++ b/msigdb_kegg/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ad05ce908ce1b057810c1ad6b5adb4b0558beecd25c1ee4aef2fd9f84708b70 +size 153189 diff --git a/msigdb_kegg/basic/plot_13.png b/msigdb_kegg/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..9211f469aac7443d2793175a0acd3b3935004b05 --- /dev/null +++ b/msigdb_kegg/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9015bf060d126e57ec49b444e4c58560fdec69150aeab0f16cec6720b6e9225c +size 145794 diff --git a/msigdb_kegg/basic/plot_14.png b/msigdb_kegg/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..c4ea95008d05481df941d4b7a472528f673fcddc --- /dev/null +++ b/msigdb_kegg/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e45395e11bbe359a5186a70f362c1f2e8198df4a9b20cf9b5e90e41fa68022a +size 136880 diff --git a/msigdb_kegg/basic/plot_15.png b/msigdb_kegg/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..4e0f89202445186f566a2373b7064d205067499e --- /dev/null +++ b/msigdb_kegg/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e9ce43de72f37522feb5334c7efd696f65961629e30e23d73536a934d6a5a52 +size 138543 diff --git a/msigdb_kegg/basic/plot_16.png b/msigdb_kegg/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..3197498eacd89812b2808398b7d48e17696fa134 --- /dev/null +++ b/msigdb_kegg/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe852f88496a86d8bc15ec705eaa84dac11aaf32e1432be42e93b3933f30d7e6 +size 146713 diff --git a/msigdb_kegg/basic/plot_17.png b/msigdb_kegg/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..0afde52c5dd7b5d7449c232fb9446ae52da71223 --- /dev/null +++ b/msigdb_kegg/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb58c316e9e73500be94e4f1984f3ac4766f131d0e2f5f2240b58556d86ee3f9 +size 142570 diff --git a/msigdb_kegg/basic/plot_18.png b/msigdb_kegg/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..3671406d80f3546745a9a49d2718e7f15c1cdb55 --- /dev/null +++ b/msigdb_kegg/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ef36cba09b756774b95aa48b27a12cb0415c9fe6a66b9f834eec9d4c2b799c0e +size 150668 diff --git a/msigdb_kegg/basic/plot_19.png b/msigdb_kegg/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..53b973b993a9555fcde568b596e0dd88b3480f38 --- /dev/null +++ b/msigdb_kegg/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb10ed25e033f56c89716595c9556bb404703d62980e49879bc5f2ee53b41d14 +size 145042 diff --git a/msigdb_kegg/basic/plot_2.png b/msigdb_kegg/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..33537e9ae58c0d238b3efcdf816ccc82971195d4 --- /dev/null +++ b/msigdb_kegg/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:96438a6af5ba176862cb2205fc0d5850e5420d0de7e25213dbe3b393b148d43d +size 137118 diff --git a/msigdb_kegg/basic/plot_3.png b/msigdb_kegg/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f082597b8f027fef474fef0341ee35900ec830b4 --- /dev/null +++ b/msigdb_kegg/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f9dd7c5df62365e41383fd15fd45ee272336e590badb359316d07fa81723d8c6 +size 135888 diff --git a/msigdb_kegg/basic/plot_4.png b/msigdb_kegg/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..c633b23d8b8ca93db3a5119e16dbfa48fa1c505c --- /dev/null +++ b/msigdb_kegg/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6dba24fa1a14c7ac6b8cbd644a6e639cb33c1ad06c61937f823356151a88cd91 +size 136759 diff --git a/msigdb_kegg/basic/plot_5.png b/msigdb_kegg/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..5cf58e8a21c80ce3c7fbfa7f267a42a19941bc4c --- /dev/null +++ b/msigdb_kegg/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a83d174fcd4cb13014da04a029bbf5aacbd28596e0ed8937167ab11ae76863c7 +size 134031 diff --git a/msigdb_kegg/basic/plot_6.png b/msigdb_kegg/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..570ec60b9fa46136f577f23dc38603b56cdc8c66 --- /dev/null +++ b/msigdb_kegg/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:662f1638742a1629aa291fc2a218e83f392b11cf30b32d62f829b781a60e6cb1 +size 137337 diff --git a/msigdb_kegg/basic/plot_7.png b/msigdb_kegg/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..a58320c4f79ae211e45e32f8cf9394fe1cc7c1fc --- /dev/null +++ b/msigdb_kegg/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5217c1f3c542e26e3e2e405fb34b314ce7db0b7011a8d0eca5fc0a8afa7416bb +size 141475 diff --git a/msigdb_kegg/basic/plot_8.png b/msigdb_kegg/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..fd9761f509f264060f9f4d6db12343a9b17ac1dc --- /dev/null +++ b/msigdb_kegg/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a80f4ae9eedfda4837f45e1be6e115a9a2b4f561d8986841a4b06d39a4e7ad90 +size 143068 diff --git a/msigdb_kegg/basic/plot_9.png b/msigdb_kegg/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..b94c67101e9ca3239efdafa2259d2c31b415263d --- /dev/null +++ b/msigdb_kegg/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e04e8c517757abd04e072c2a73e552fcf50f8fc0b94e6e83b9ccf6cf2c9e5e04 +size 141009 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0105c67d44b59ac2a894d0dbd625216f59d11ce5 --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cbeba29745a17071c2db9a5db40cc1e13012987bd71d415396af6f1e8a3b9c9 +size 72408 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..03beffd00556f689479fe9f3260dddd2e591247a --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Steroid biosynthesis 5 8 2.228457897998285 0.025849995892581 4.451456310679611 10.919902912621358 0.8535439655720318 0.1867209176898754 2.1463612955879627 1.3314318120676296 1.5430058140543457 0.1933818217769055 0.0007425743792719 0.0639684350193291 0.0075668597133861 0.0040998381065295 2.7323384312904545e-05 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..62cfb731c38c84cac88a238f2c387eddd9f40ea8 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 179, + "title": "Average number of proteins per term", + "value": 14.603351955307263 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..10148642a8a7829b56963585ef5d84b9dc9cf587 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8e7a5fd2ef23ec5554f2d1784beaf95210fda17e --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,81 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Renin angiotensin system 0.8782936287474641 2.4821200787724043 0.0130603255938404 0.9049354097906096 0.2612458377935888 4 Q9UIQ6,P52888 2 +Alpha linolenic acid metabolism 0.8740213523131766 2.471060727624604 0.0134712940253902 0.911764955860742 0.2612458377935888 2 O15254 1 +Graft versus host disease 0.8397435897435863 2.3176205558744583 0.0204699520373763 0.9753294085981709 0.2612458377935888 4 P49327,P01889,P10321 3 +Allograft rejection 0.8397435897435863 2.3176205558744583 0.0204699520373763 0.9753294085981709 0.2612458377935888 4 P49327,P01889,P10321 3 +Autoimmune thyroid disease 0.8397435897435863 2.3176205558744583 0.0204699520373763 0.9753294085981709 0.2612458377935888 4 P49327,P01889,P10321 3 +Cytokine cytokine receptor interaction 0.8257481192268923 2.261329719236292 0.0237388472272421 0.9864382578817948 0.2612458377935888 3 P15260 1 +Steroid biosynthesis 0.8209971961883791 2.228457897998285 0.025849995892581 0.9907949793266336 0.2612458377935888 8 Q16850,Q15800,P48449,Q15392,Q14534 5 +Gap junction 0.7596779153753451 1.9533318264284003 0.0507802886032324 0.9999111519461604 0.3635868663991445 13 P07437,Q9BVA1,P68371 3 +Biosynthesis of unsaturated fatty acids 0.7427261738383517 1.874568828299705 0.0608520649036383 0.9999868360136086 0.3906412733137298 8 Q9BY49,O15254,Q9NZ01 3 +Nicotinate and nicotinamide metabolism 0.7377959109143764 1.8566099657407489 0.0633666650645066 0.9999918537028114 0.391125277467127 6 Q13423 1 +Ether lipid metabolism 0.7150192431519684 1.763784841807085 0.0777682105140797 0.9999994914006348 0.4285455559074111 4 O00116 1 +Type i diabetes mellitus 0.7099824680549317 1.7345897433717568 0.082813497471057 0.999999809488921 0.4285455559074111 5 P49327,P01889,P10321 3 +Riboflavin metabolism 0.7087853674632134 1.7290853329576474 0.0837938237807787 0.9999998426794354 0.4285455559074111 5 Q9NPH0 1 +Huntingtons disease 0.4831985133497983 1.6880509394717496 0.0914014509725185 0.9999999646332648 0.4544683256689114 73 P00403,P13073,P47985,O14949,O43676,O75306,P21796,P42858,O96000,P24539,Q9UDW1,P45880,P14406,Q9Y6M9,Q9Y277 15 +Oxidative phosphorylation 0.5839314255228443 1.6136735424533504 0.1065982556754474 0.9999999982726652 0.4980809498990147 55 P00403,P13073,O75964,Q7KZN9,P47985,O43676,O14949,O75306,Q93050,O96000,P24539,P03886,Q9UDW1,P56134,P14406,Q9Y6M9,Q9Y487 17 +Calcium signaling pathway 0.6864960853073331 1.6048790247861815 0.1085204304249249 0.9999999988252656 0.4980809498990147 15 Q13555,P12235,P16615,P21796,P45880,Q9Y277 6 +Pathogenic escherichia coli infection 0.673275564581932 1.5444131906730196 0.1224882665362008 0.9999999999304536 0.5263171057808803 18 P07437,Q9BVA1,P68371 3 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.6611203054521458 1.5151368493364803 0.1297377515055859 0.9999999999842464 0.5263171057808803 4 Q92643,O43292 2 +Parkinsons disease 0.5954694484178039 1.507366435282889 0.1317167572431783 0.9999999999895192 0.5263171057808803 49 P00403,P13073,P47985,O14949,O43676,O75306,P21796,O96000,P24539,P03886,Q9UDW1,P45880,P14406,Q9Y6M9,Q9Y277 15 +Abc transporters 0.6565183678245435 1.4936976034233036 0.1352546752286061 0.9999999999949536 0.5263171057808803 4 O75027,P33527 2 +P53 signaling pathway 0.6467013336062039 1.4142371573784795 0.157292281434179 0.9999999999999504 0.5745983342187357 11 P11802,O14681,P49327,O95067,O96017 5 +Glycerophospholipid metabolism 0.626349820410842 1.3088397088083488 0.190588652957842 1.0 0.6396443115138636 14 Q92604,Q8NCC3,Q96N66,Q8NF37,O96017,P35790,P43304,O15228,Q99943 9 +O glycan biosynthesis 0.6155699451972139 1.3018568572249156 0.1929653230265287 1.0 0.6396443115138636 4 Q10472,O43505 2 +Protein export 0.6164833943915321 1.2600100031100037 0.2076657537201671 1.0 0.6485876418212383 14 P67812,Q9Y5M8,Q15070,Q15005 4 +Natural killer cell mediated cytotoxicity 0.6126431997661808 1.2409891658436791 0.2146097512140885 1.0 0.6511041604630822 14 Q02750,Q06124,P15260,P49327,P01889,P10321 6 +Epithelial cell signaling in helicobacter pylori infection 0.5946264261859302 1.1478388381468727 0.2510351008410008 1.0 0.7247626298474055 20 Q93050,Q9Y487 2 +Ppar signaling pathway 0.5765989610378763 1.0731280647768566 0.2832136605786244 1.0 0.7921132069308401 11 P23786 1 +Neurotrophin signaling pathway 0.5763962162506151 1.0606473789131796 0.2888501822907301 1.0 0.7954489635390876 24 Q13555,Q06124,P31751,Q15418,P51812 5 +Jak stat signaling pathway 0.5647752916259149 1.038061265320957 0.2992415332835745 1.0 0.8115793099660581 7 Q06124,P15260 2 +Non small cell lung cancer 0.5567012686125119 0.9931412585625328 0.3206411199110395 1.0 0.8314485473018493 8 Q02750,P31751,P11802 3 +Melanoma 0.5535253783049183 0.984556333256281 0.3248420476976785 1.0 0.8314485473018493 7 Q02750,P31751 2 +Porphyrin and chlorophyll metabolism 0.5497743387105357 0.9380841349173196 0.3482011743067161 1.0 0.8660978330228477 12 Q7KZN9,Q5JPH6,P09601,P36551,P30519 5 +Primary bile acid biosynthesis 0.5338078291814933 0.9377467988312136 0.3483745473611455 1.0 0.8660978330228477 2 P51659 1 +Glioma 0.5446020773970807 0.9178858190744972 0.3586786465861862 1.0 0.8704673726680805 11 Q02750,Q13555,P11802,P42345,P05771,P08069,P31751 7 +Mtor signaling pathway 0.5417738492570285 0.9156356625183562 0.3598580199856869 1.0 0.8704673726680805 9 P51812,P31751,Q15418 3 +Cardiac muscle contraction 0.5404921356575966 0.8704649825343563 0.3840463478314047 1.0 0.904907989112114 23 P00403,P13073,P47985,P16615,O14949,Q9UDW1,P15954,P05023,P09493,P14406 10 +Small cell lung cancer 0.5169891017855085 0.8201107562681895 0.4121529709120914 1.0 0.9200073752790834 6 P31751 1 +Cell adhesion molecules cams 0.5130221410252083 0.786426025958332 0.4316179410865164 1.0 0.9200073752790834 8 P01889,P04439,P10321 3 +Glycine serine and threonine metabolism 0.5100772771096287 0.7801631988022854 0.4352948208289082 1.0 0.9200073752790834 7 P23378,O43175 2 +Long term potentiation 0.5170316566214428 0.7801233924871199 0.4353182486075249 1.0 0.9200073752790834 12 Q13555,P51812,Q15418 3 +Vibrio cholerae infection 0.5203898562092938 0.7704547406339148 0.4410301925413389 1.0 0.9200073752790834 19 Q9Y487 1 +Bladder cancer 0.4991898655873184 0.7577373056678945 0.4486082611072655 1.0 0.9200073752790834 4 Q02750 1 +Progesterone mediated oocyte maturation 0.5084992386662146 0.7063748662798157 0.4799550467454891 1.0 0.9347363057832518 25 Q02750,Q9UJX4,P31751,Q9UJX6,Q15418,O95067,P51812 7 +Sphingolipid metabolism 0.497541819119485 0.7003637407496472 0.4837001744085332 1.0 0.9347363057832518 10 O95470,O15269 2 +Erbb signaling pathway 0.498699121570766 0.6992937207611899 0.4843684904014003 1.0 0.9347363057832518 11 Q02750,P31751,P05771,Q13555 4 +Dilated cardiomyopathy 0.4936211300408614 0.6891476878193432 0.490730332783134 1.0 0.9347363057832518 9 P16615 1 +Alzheimers disease 0.458757303975895 0.658981129837195 0.5099078862285404 1.0 0.9418145042495122 52 P00403,P13073,P47985,P16615,O14949,O43676,O75306,O96000,P24539,P49327,Q9UDW1,P14406,Q9Y6M9 13 +Chronic myeloid leukemia 0.491216607779107 0.6582636150193683 0.5103687536994563 1.0 0.9418145042495122 12 Q02750,P31751,P11802,Q06124 4 +Endometrial cancer 0.4810306307389422 0.639141191154715 0.5227310854808436 1.0 0.9547843296027654 8 Q02750,P31751 2 +Hypertrophic cardiomyopathy hcm 0.4784767192591636 0.6127225800111427 0.5400597896440618 1.0 0.9764717408715864 10 P50402,P16615,P09493 3 +Metabolism of xenobiotics by cytochrome p450 0.4663676732511005 0.5817076722642849 0.5607636027858647 1.0 1.0 7 P21266,O14880,P07099 3 +Apoptosis 0.4546511751904167 0.4797226625402365 0.6314246111332962 1.0 1.0 14 P31751,O95831 2 +N glycan biosynthesis 0.4478180586658346 0.4559466964840243 0.6484283090669776 1.0 1.0 13 Q9BT22,P46977,P04843 3 +Peroxisome 0.4574804543890298 0.4499569512663673 0.652741481334838 1.0 1.0 27 Q9BY49,Q15067,O00116,O75874,P48735,O15254,P40855 7 +Fatty acid metabolism 0.4547494396302277 0.4386374473930411 0.6609242585524282 1.0 1.0 25 P51648,O15254,P23786,P30837,Q9BWD1,Q92947 6 +Long term depression 0.430161689424405 0.4104705859613543 0.6814607762547225 1.0 1.0 9 Q02750,P05771,Q14344,P30154 4 +Vegf signaling pathway 0.4247167915199736 0.3726812795041596 0.7093856711055988 1.0 1.0 11 P04792,P31751 2 +Cysteine and methionine metabolism 0.4199886451592393 0.3325020041971939 0.7395102265821518 1.0 1.0 14 Q13126 1 +Colorectal cancer 0.4086650412987898 0.3090747527512494 0.7572646639490559 1.0 1.0 11 Q02750,P31751,Q9UJX6 3 +Ecm receptor interaction 0.3880384478462127 0.3050409301240314 0.7603349791983902 1.0 1.0 3 Q7L0J3,Q08722 2 +Fc epsilon ri signaling pathway 0.3969703348619213 0.2808533000349671 0.7788229206438901 1.0 1.0 9 Q02750,P31751 2 +Melanogenesis 0.3940911499605274 0.2786821635273497 0.7804887518822743 1.0 1.0 8 Q02750,Q13555 2 +Antigen processing and presentation 0.3976138355472293 0.2326529373276712 0.8160309169650177 1.0 1.0 16 P01889,P10321,P04439,P61289 4 +Viral myocarditis 0.3822196293186138 0.228266133344092 0.819439351241452 1.0 1.0 9 P01889,P10321 2 +Oocyte meiosis 0.4051083443666904 0.2103013821244252 0.8334324566300033 1.0 1.0 38 Q13555,Q02750,P30154,Q15418,O95067,P51812 6 +Thyroid cancer 0.3735108625690435 0.2071691774377575 0.8358777379539073 1.0 1.0 8 Q02750 1 +Proteasome 0.4053522557774569 0.2059222055657351 0.83685167962207 1.0 1.0 34 P49721,P60900,P28074,P28072,Q99436 5 +T cell receptor signaling pathway 0.3746408315588005 0.1868058789009204 0.8518128373640674 1.0 1.0 11 Q02750,P31751 2 +Tryptophan metabolism 0.3794078915768373 0.1809179133217466 0.8564320080729624 1.0 1.0 14 Q9BWD1,P51648,Q92947 3 +Gnrh signaling pathway 0.3674049205238669 0.1790799156847154 0.8578749520352411 1.0 1.0 9 Q02750,Q13555 2 +Toll like receptor signaling pathway 0.3564372375496136 0.1373078501185063 0.890787465711685 1.0 1.0 10 Q02750,P31751 2 +Hedgehog signaling pathway 0.326806692773233 0.1159649066630265 0.907680354529918 1.0 1.0 3 Q9ULC3,P48729 2 +Rig i like receptor signaling pathway 0.3320270751692154 0.1110591696072479 0.911569426317178 1.0 1.0 5 Q14258,Q9UHD2,Q16539,O00571 4 +Renal cell carcinoma 0.3515421189334559 0.0868828787308738 0.9307646088447132 1.0 1.0 15 P31751,Q15369,Q06124 3 +Prostate cancer 0.3371566158638184 0.0688806597116241 0.9450846132642684 1.0 1.0 12 P31751 1 +Aldosterone regulated sodium reabsorption 0.3176929399519383 0.0521177992877239 0.958434830459121 1.0 1.0 8 Q96PU5,P05023,P05771 3 +B cell receptor signaling pathway 0.3118580994368739 0.0395485704391089 0.9684530301727428 1.0 1.0 8 Q02750,P31751 2 +Drug metabolism cytochrome p450 0.2890235210263673 0.0113768115126601 0.9909228135561308 1.0 1.0 6 Q9Y2Q3,P11766,P78417,P21266,O14880 5 +Sulfur metabolism 0.2718504431826593 0.0074877410541714 0.994025702843728 1.0 1.0 3 O43252 1 +Valine leucine and isoleucine biosynthesis 0.2901960784313651 0.0061590509843945 0.995085819379387 1.0 1.0 7 P26640,Q9P2J5,Q15031,P41252,P08559,Q9NSE4 6 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6770a335fbdb270daf048ead05e112dcb62ffd27 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AACS", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN4", "ADAR", "ADH5", "ADI1", "ADK", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "APPL1", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "B3GALT6", "B4GAT1", "BAIAP2", "BCAS2", "BDH2", "BIRC6", "BLVRA", "BLVRB", "BNIP1", "BPNT1", "BUB1B", "BUB3", "BUD31", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CBR1", "CCDC6", "CCNB1", "CCNB2", "CD47", "CDC16", "CDC23", "CDC27", "CDC42", "CDC5L", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDS2", "CFL1", "CFL2", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHORDC1", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT7", "CNOT9", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPOX", "CPT2", "CRKL", "CRNKL1", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DARS", "DARS2", "DBT", "DCPS", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPM1", "DPYSL2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "ELOC", "EMD", "ENAH", "ENDOD1", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "EPS15", "ERCC2", "ERCC3", "ERCC4", "ERO1A", "EXO1", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAH", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GCAT", "GCDH", "GCLM", "GFPT1", "GGA2", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GRB2", "GRHPR", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HDAC1", "HDAC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFNGR1", "IGF1R", "IGF2BP1", "IGF2R", "IMPDH2", "IQGAP1", "IQGAP2", "IQSEC1", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDSR", "LAMP1", "LAP3", "LARS", "LARS2", "LCLAT1", "LDHA", "LDHB", "LIG3", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LYPLA1", "M6PR", "MAD2L1", "MANBA", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MFSD8", "MGAT1", "MGST3", "MID1", "MIF", "MOGS", "MPG", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR6", "MTOR", "MTR", "MUT", "MYH10", "MYH9", "MYL6", "MYL6B", "NAE1", "NAGLU", "NAMPT", "NANS", "NARS", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NEDD4L", "NEFM", "NF1", "NIT2", "NLN", "NME1", "NNT", "NPC1", "NPC2", "NSD2", "NSDHL", "NSF", "NT5C2", "NUDT12", "NUDT5", "NUDT9", "OAT", "OCRL", "OGDH", "ORC2", "ORC3", "ORC5", "OXA1L", "OXCT1", "P4HA1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PECR", "PEX14", "PEX19", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHF5A", "PHGDH", "PI4KA", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PKM", "PLA2G15", "PLCG1", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PMPCA", "PNP", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "PPA1", "PPA2", "PPAT", "PPID", "PPIH", "PPIL1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPT1", "PPT2", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRSS3", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QPRT", "RAB13", "RAB23", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAC1", "RAD21", "RAD23B", "RAD50", "RALA", "RAPGEF2", "RARS", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RBPJ", "RCOR1", "RDH11", "RDX", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RIPK1", "RNASEH2A", "RNASEH2B", "ROCK1", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RSL24D1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC63", "SEPHS1", "SETD2", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC38A1", "SLC9A6", "SLIT2", "SLK", "SLTM", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SNAP23", "SNAP29", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SV2A", "SYMPK", "TAB1", "TAF2", "TAF5", "TAF6L", "TALDO1", "TAOK1", "TARS", "TARS2", "TBK1", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TK1", "TKT", "TLN1", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRA2A", "TRA2B", "TRIM21", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSPO", "TSTA3", "TTC37", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TXNDC12", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR5", "UGDH", "UGP2", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USP39", "USP8", "VAMP7", "VAPA", "VARS1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS4A", "VPS4B", "VTA1", "WARS", "WARS2", "WBP11", "WDR61", "XAB2", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX3", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ACAT2", "ACOX1", "ACOX3", "ACP6", "ADH5", "AGPAT1", "AGPS", "AIFM1", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "ANAPC2", "ANAPC5", "ATP1A1", "ATP2A2", "ATP5F1", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "B4GAT1", "CAMK2G", "CCNB2", "CD47", "CDK4", "CHEK2", "CHKA", "COX15", "COX2", "COX4I1", "COX7A2", "COX7C", "CPOX", "CPT2", "CSNK1A1", "CYP51A1", "DDX3X", "DHCR24", "EARS2", "EI24", "ELOC", "EMD", "EPHX1", "FASN", "GALNT1", "GCDH", "GLDC", "GNA13", "GNPAT", "GPAA1", "GPD2", "GSTK1", "GSTM3", "GSTO1", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HSD17B4", "HSPB1", "HTT", "IARS", "IARS2", "IDH1", "IDH2", "IFNGR1", "IGF1R", "LARS", "LARS2", "LNPEP", "LPCAT1", "LPGAT1", "LSS", "MAP2K1", "MAPK14", "MBOAT7", "MGST3", "MSMO1", "MTAP", "MTOR", "ND1", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NEDD4L", "NNT", "OXA1L", "PAPSS1", "PDHA1", "PECR", "PEX19", "PHGDH", "PIGK", "PLA2G15", "PPP2R1B", "PRKCB", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PSME3", "PTPN11", "RAB23", "RPN1", "RPS6KA1", "RPS6KA3", "SEC11A", "SGPL1", "SLC25A4", "SPCS2", "SPTLC1", "SQLE", "SRPRB", "STT3A", "SV2A", "TBK1", "TECR", "THOP1", "TPM1", "TRIM25", "TUBB", "TUBB2B", "TUBB4B", "UQCR10", "UQCRFS1", "UQCRQ", "VARS1", "VDAC1", "VDAC2", "VDAC3"]} \ No newline at end of file diff --git a/msigdb_reactome/advanced/idx2term.json b/msigdb_reactome/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..4da52471b14ee202d37a4410b3da25e520cc65d7 --- /dev/null +++ b/msigdb_reactome/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport of small molecules", "1": "Deubiquitination", "2": "Assembly and cell surface presentation of nmda receptors", "3": "Protein localization", "4": "The citric acid tca cycle and respiratory electron transport", "5": "Organelle biogenesis and maintenance", "6": "Cytokine signaling in immune system", "7": "Selective autophagy", "8": "Mitotic g2 g2 m phases"} \ No newline at end of file diff --git a/msigdb_reactome/advanced/plot_0.png b/msigdb_reactome/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..37ee3e13cbc806190c03753d5bebe43ecc71c989 --- /dev/null +++ b/msigdb_reactome/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64d1f71979591c9cfe0defac828c8026b5f95240c03f3d759470f37dfe0bc1d2 +size 218167 diff --git a/msigdb_reactome/advanced/plot_1.png b/msigdb_reactome/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..045637f95c0547e1c59c508c1374f735dab0aebb --- /dev/null +++ b/msigdb_reactome/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5bc2c4fd10674dd9e41ac8312c5d470968357e7cc2227f58ddb3b30490f3036a +size 206426 diff --git a/msigdb_reactome/advanced/plot_2.png b/msigdb_reactome/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0b897b856256162a03246cf983313aab2f81e737 --- /dev/null +++ b/msigdb_reactome/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa21c607bdd80b9b9a2a96d23851c1b906876275bb7fc3ffa6f2016fe6a3d1c9 +size 193420 diff --git a/msigdb_reactome/advanced/plot_3.png b/msigdb_reactome/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..85057d1f2c1cf86a49511922be3692287a9267b8 --- /dev/null +++ b/msigdb_reactome/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:32e3dec47030dc20631b283d8d52018f16ecfdf07f8fa48015a7127476e613cf +size 207012 diff --git a/msigdb_reactome/advanced/plot_4.png b/msigdb_reactome/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..183c8b7060703bdd8eccac0f41db3b96c3d2a926 --- /dev/null +++ b/msigdb_reactome/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9faab2057c1a3caccfdc10644f0ea4eb07f65d1cc550b65fc2360749331ba78d +size 207419 diff --git a/msigdb_reactome/advanced/plot_5.png b/msigdb_reactome/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..31fa1cdff9009c4e22ec8926e8ff971e47242758 --- /dev/null +++ b/msigdb_reactome/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ac3ef509b824db5d743a5bb3e20b48bd99bf7c9d626f7127d1493338b4d2cb8 +size 210459 diff --git a/msigdb_reactome/advanced/plot_6.png b/msigdb_reactome/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..a5d3b5bba0b52770197aa242f4f6246e4ab81c60 --- /dev/null +++ b/msigdb_reactome/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:204e51d9f28288fbf282f491d354b1b8bc04707f45dc357b6379247018b08e57 +size 216090 diff --git a/msigdb_reactome/advanced/plot_7.png b/msigdb_reactome/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..1054e4f2f2fff5409685b69648c57dce3875ae04 --- /dev/null +++ b/msigdb_reactome/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7c0834a9e7f00cf5b976418d9dd4497a2f0302801559a9d058f95666efe9984 +size 200482 diff --git a/msigdb_reactome/advanced/plot_8.png b/msigdb_reactome/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..cfd09707517c6620a52a5301a6ad3a08977367b9 --- /dev/null +++ b/msigdb_reactome/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:017c4392645f18bb272b5708ab6bec185bb316068843cada85c66cee3321370a +size 207124 diff --git a/msigdb_reactome/basic/idx2term.json b/msigdb_reactome/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ee3ac83f53bee05f026b01df75a31e3dc4600b7c --- /dev/null +++ b/msigdb_reactome/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport of small molecules", "1": "Deubiquitination", "2": "Assembly and cell surface presentation of nmda receptors", "3": "Protein localization", "4": "The citric acid tca cycle and respiratory electron transport", "5": "Organelle biogenesis and maintenance", "6": "Cytokine signaling in immune system", "7": "Selective autophagy", "8": "Mitotic g2 g2 m phases", "9": "Mitotic prometaphase", "10": "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "11": "Signaling by interleukins", "12": "Signaling by receptor tyrosine kinases", "13": "Activation of nmda receptors and postsynaptic events", "14": "Mapk family signaling cascades", "15": "Ub specific processing proteases", "16": "Mitotic metaphase and anaphase", "17": "Mitochondrial protein import", "18": "Interferon gamma signaling", "19": "Class i mhc mediated antigen processing presentation", "20": "Recruitment of numa to mitotic centrosomes", "21": "Interferon alpha beta signaling", "22": "Glycerophospholipid biosynthesis", "23": "Adaptive immune system", "24": "M phase", "25": "Antigen presentation folding assembly and peptide loading of class i mhc", "26": "Antigen processing ubiquitination proteasome degradation", "27": "Regulation of tp53 expression and degradation", "28": "Slc mediated transmembrane transport", "29": "Autophagy", "30": "Metabolism of lipids", "31": "Separation of sister chromatids", "32": "Gpcr ligand binding", "33": "Cristae formation", "34": "The role of gtse1 in g2 m progression after g2 checkpoint", "35": "Formation of atp by chemiosmotic coupling", "36": "Hedgehog off state", "37": "Signaling by gpcr", "38": "Phospholipid metabolism", "39": "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "40": "Regulation of plk1 activity at g2 m transition", "41": "Signaling by hedgehog", "42": "Neurotransmitter receptors and postsynaptic signal transmission", "43": "Cholesterol biosynthesis", "44": "Cilium assembly", "45": "Nuclear envelope ne reassembly", "46": "Ion channel transport", "47": "Neuronal system", "48": "Stimuli sensing channels", "49": "Transmission across chemical synapses"} \ No newline at end of file diff --git a/msigdb_reactome/basic/plot_0.png b/msigdb_reactome/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..bb7a6e41b5e7cbcd7b78381142279551ff886c5e --- /dev/null +++ b/msigdb_reactome/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:681266e02b3a0baa1843ea81c7b38722e5f2fb44380408de2c50caee1e1e24fc +size 143325 diff --git a/msigdb_reactome/basic/plot_1.png b/msigdb_reactome/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..6d7ed46ec4a4d971f2ba9c2ee42f052895b5dba0 --- /dev/null +++ b/msigdb_reactome/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1a8c150fba7f6cbcee7f589a26d623872ca2c1063e3defe19fc4d948d38a71d +size 139038 diff --git a/msigdb_reactome/basic/plot_10.png b/msigdb_reactome/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..5661719756ca8e3e7a8ac0736c956b4044ae0e19 --- /dev/null +++ b/msigdb_reactome/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da32dbf55e0f807c5e74f0df61113ee885827000d6f9395491c4fec3b44c7ebb +size 132239 diff --git a/msigdb_reactome/basic/plot_11.png b/msigdb_reactome/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..b5620ade64cf7be1379fa7b8d6ce1bd7165c3888 --- /dev/null +++ b/msigdb_reactome/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ebef9c960f5c7d62a23d96a7abd8f5fb16d7da20ed7447175189532126513763 +size 141586 diff --git a/msigdb_reactome/basic/plot_12.png b/msigdb_reactome/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..333199ff7f9e3cd4eccc7ac38abc1d336d8aa822 --- /dev/null +++ b/msigdb_reactome/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8600b328ba7a113974a5573f8b49b9d64a24a0aaeb6bcb05c9cfdf1bc8d76446 +size 150262 diff --git a/msigdb_reactome/basic/plot_13.png b/msigdb_reactome/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..5fc0b55f024869f71097b2938e9c58f4975cbdee --- /dev/null +++ b/msigdb_reactome/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0ccd61dd2b6441b1df2f8f2fea24124aa5a9af2f2243c529abf7f584a71da1d +size 142983 diff --git a/msigdb_reactome/basic/plot_14.png b/msigdb_reactome/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..39d3916fb9371d202a25a89ff5cae9107e779a7a --- /dev/null +++ b/msigdb_reactome/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6bbde95c52ec297a70b766f63eea10933e0eb694d119a2718ef3a35ccf67a21 +size 145505 diff --git a/msigdb_reactome/basic/plot_15.png b/msigdb_reactome/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..3ddca8518986021b7945b4eb32e4d27c7a17db40 --- /dev/null +++ b/msigdb_reactome/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:af4b2bda5344a8ee367ab44e20e13fb03de75361db3bf38ec43be1113252515f +size 147907 diff --git a/msigdb_reactome/basic/plot_16.png b/msigdb_reactome/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..76ae9db817b30ccd9c4279eae64dc6034308c88b --- /dev/null +++ b/msigdb_reactome/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:03c1c7b8c0192e83185733d5aa43905af1e7cbbf4017edf6151c5338a59767e3 +size 144367 diff --git a/msigdb_reactome/basic/plot_17.png b/msigdb_reactome/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..95701b3e877c38f3ec10e573fd6876a83e4f3b95 --- /dev/null +++ b/msigdb_reactome/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:099ff07815886127bc46d3d064b5a10bb9f5c2c39e0cdd33960bb3dda6dbf88e +size 135721 diff --git a/msigdb_reactome/basic/plot_18.png b/msigdb_reactome/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..daa7b7c62337e8e4a26fe83bf23c0fbfe377430c --- /dev/null +++ b/msigdb_reactome/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7a02e0a29a14783861f3b20b054db47e9bf31df3f47ff27f4743309c75677a7e +size 137313 diff --git a/msigdb_reactome/basic/plot_19.png b/msigdb_reactome/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..c85137ca21469f2cf7940212d189a9edb5a091cf --- /dev/null +++ b/msigdb_reactome/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c90a714f61bbdddab6965f246c51620b3f86dc0af6eaa233deb3d2b1358b4fd +size 146439 diff --git a/msigdb_reactome/basic/plot_2.png b/msigdb_reactome/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9d8b1b79ac332677291c213bbf518162d5172bf9 --- /dev/null +++ b/msigdb_reactome/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8adf51a7217a9b259cfbd264eeec1c5bce189b09e56e6581891634a6a3bde5c8 +size 142406 diff --git a/msigdb_reactome/basic/plot_20.png b/msigdb_reactome/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..1ca38a094288b422c0f61971f05a375edcbcf015 --- /dev/null +++ b/msigdb_reactome/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53119723fb132f48328a6c3a7942ac67111c398403434cb7a7d37325fdb1e619 +size 140317 diff --git a/msigdb_reactome/basic/plot_21.png b/msigdb_reactome/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..176c7034f6d0a92660efca26f1f6686edfd17729 --- /dev/null +++ b/msigdb_reactome/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:23cf7af06e6628873f9fac1803a34188ef1870bbd0d69a0c1afbd6d379eee117 +size 137129 diff --git a/msigdb_reactome/basic/plot_22.png b/msigdb_reactome/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..51464b6fdb5d4aade584677eafab242693bf8073 --- /dev/null +++ b/msigdb_reactome/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7f5442f1cac8b5f79e50ec9e241a05729d00bbd969613ec671ba997c9b76148 +size 140757 diff --git a/msigdb_reactome/basic/plot_23.png b/msigdb_reactome/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..ab52f4a62be2256eca7cd27355cdbfc739808f7e --- /dev/null +++ b/msigdb_reactome/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae6509f0f9c919b16bcade511da78ba88e736675da44541f52c92ad0f33cdff7 +size 139717 diff --git a/msigdb_reactome/basic/plot_24.png b/msigdb_reactome/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..28b9288de9596e56ea67c7d059ccf087e42c8402 --- /dev/null +++ b/msigdb_reactome/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a67ed97b3bd1969c88a86cdce51140f94ccae8635193df746b613d88fee19c3b +size 133132 diff --git a/msigdb_reactome/basic/plot_25.png b/msigdb_reactome/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..ac6c902ff7a65707ec7b1afc1411fdf68d43e8f5 --- /dev/null +++ b/msigdb_reactome/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cae6c76980bb4dab465263ea16b0668375fc4fc0555c60c2286061a472c4bc6b +size 138413 diff --git a/msigdb_reactome/basic/plot_26.png b/msigdb_reactome/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..9dce403c99d2e8ad8bd1ebfe8f235b6d3b5762a0 --- /dev/null +++ b/msigdb_reactome/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e86cd754541e693f09cc58f1d51eb8cfce8407d140ad48e687301ed8db33b05 +size 146876 diff --git a/msigdb_reactome/basic/plot_27.png b/msigdb_reactome/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..aeb2c0a6b0ced419c246cc0ce6ae4b73cab623b1 --- /dev/null +++ b/msigdb_reactome/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4359e0c9f0eccc20eb10785c044c7bcca42dd236968065866fb66455fee82279 +size 140071 diff --git a/msigdb_reactome/basic/plot_28.png b/msigdb_reactome/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..6393bf9884fd9dbc576ec30c025cb2d0ce674531 --- /dev/null +++ b/msigdb_reactome/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d899357d689c91a551a50cb434e866b708aefc74c24d5de47617f99d458a0094 +size 140228 diff --git a/msigdb_reactome/basic/plot_29.png b/msigdb_reactome/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..9a9701c7d8252e597e4f10ee0a745249fa584204 --- /dev/null +++ b/msigdb_reactome/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:87ff1cfee4f6f1c2e672d26999355c670162ed2d1ee1900c29f23317ed832480 +size 130521 diff --git a/msigdb_reactome/basic/plot_3.png b/msigdb_reactome/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..3904707645e26032c19bec73ed1d97dcf2450952 --- /dev/null +++ b/msigdb_reactome/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a734cd3729f1e0c7e1c17baa4b65173625e5d7319f7a421a8243b0e13d161732 +size 133920 diff --git a/msigdb_reactome/basic/plot_30.png b/msigdb_reactome/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..e1b454d990152778860601741d0ad074b4cf2a5e --- /dev/null +++ b/msigdb_reactome/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fae987b560ebc3c3cd2dd73b4f2e6c711d165204cfadeb43dcc41f16ba51ec49 +size 134977 diff --git a/msigdb_reactome/basic/plot_31.png b/msigdb_reactome/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..4cd3dfbf8443d43f321769652a57bcd08547fd4b --- /dev/null +++ b/msigdb_reactome/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a336fc3b3231ec54feff8536ee95686472c507632103f058b335706aeb60580 +size 148133 diff --git a/msigdb_reactome/basic/plot_32.png b/msigdb_reactome/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..3392046e50e53624ace9a9e60f6a264339a744d8 --- /dev/null +++ b/msigdb_reactome/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f0f137d1e104432783863cdf986629554c0d2a32b3104520196e54d1c91c931 +size 133937 diff --git a/msigdb_reactome/basic/plot_33.png b/msigdb_reactome/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..51a5db22e00dd016f07dd323676eb23d1ee93e40 --- /dev/null +++ b/msigdb_reactome/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9bb56cee9a8193f10e1b41d092acb650ff932d58940744aa31b27525d3d1a3aa +size 133232 diff --git a/msigdb_reactome/basic/plot_34.png b/msigdb_reactome/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..431a5efd88155dcea09c81aeb30732b7cf921793 --- /dev/null +++ b/msigdb_reactome/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:604c9a56504abd49c03bdc51ccd2ecff6ced69468760c970221e5cc7cc278b71 +size 142081 diff --git a/msigdb_reactome/basic/plot_35.png b/msigdb_reactome/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..d0b73377c94cb2d8a97e7a7f71517924dfd774e3 --- /dev/null +++ b/msigdb_reactome/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6daf14ca4e967c7079ad185a8b9966fe4445c82b3b48f63c1989eb6cb672e141 +size 144529 diff --git a/msigdb_reactome/basic/plot_36.png b/msigdb_reactome/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..03f73eb7dab5354d8a451b2b05c7c985e93c18b2 --- /dev/null +++ b/msigdb_reactome/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7dc2b64e6075e5997d1b424ceb5b55b268cd31b0285e697b1b54c35a7cca5278 +size 137126 diff --git a/msigdb_reactome/basic/plot_37.png b/msigdb_reactome/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..dcf8f04afcb9efe6e3187fd9b32899c7083f6cb2 --- /dev/null +++ b/msigdb_reactome/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6cf7436128869c1615d71317ba0a131ca2cef3eb905ea54fcfed53e1865fa096 +size 135680 diff --git a/msigdb_reactome/basic/plot_38.png b/msigdb_reactome/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..2440d7afd3de3e7863844e95ab92156591f7a7b0 --- /dev/null +++ b/msigdb_reactome/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:034ee9f0b6c7f8dc9ad9acb2a9316f0dd928be55b421b8acf2d7351f03988cbe +size 138861 diff --git a/msigdb_reactome/basic/plot_39.png b/msigdb_reactome/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..9ab104e39c237e9ae2c4ddfcae0af6f61098b5b3 --- /dev/null +++ b/msigdb_reactome/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7916992ab71d38f40c50eb236c82ce6e4f15803c044a698e50ea35564a69428 +size 144872 diff --git a/msigdb_reactome/basic/plot_4.png b/msigdb_reactome/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..a2c68f7abe1e2282858f0529056cb6f82b359d59 --- /dev/null +++ b/msigdb_reactome/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1df4984cb1456be3b256a4998a67b22509e7b9694b7f11c60d1e696eb06b27c1 +size 147682 diff --git a/msigdb_reactome/basic/plot_40.png b/msigdb_reactome/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..17269d961f11d9198bb601642c3a30d397c6bf78 --- /dev/null +++ b/msigdb_reactome/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6daaabd1570bdb25abb642f22d0d4a099f7113f477e7ff139ba14f010fc2a3dd +size 141034 diff --git a/msigdb_reactome/basic/plot_41.png b/msigdb_reactome/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..9db9dcf78a10acdeae3b897b86032abdb32e74e8 --- /dev/null +++ b/msigdb_reactome/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7071b900126451c47af89acd44de97133225077bfaaa9dbf0ba6925f170816a0 +size 139182 diff --git a/msigdb_reactome/basic/plot_42.png b/msigdb_reactome/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..89065dce193dca7fa3c757ff13dd27bdc1a13a5b --- /dev/null +++ b/msigdb_reactome/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:331a9ccb045bd4ce2c757533e1ec15773659d2e3b3656ef2673d15fb761121b0 +size 143786 diff --git a/msigdb_reactome/basic/plot_43.png b/msigdb_reactome/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..155f7c03b4224b7dd569048d9eb87fffb019c907 --- /dev/null +++ b/msigdb_reactome/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aab6adb68814805db67dc0f8148513e243de1d29a983fc1344622c1a63c7073b +size 138065 diff --git a/msigdb_reactome/basic/plot_44.png b/msigdb_reactome/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..c8d0c0e31553688f4426c0b15b6070dc2d529580 --- /dev/null +++ b/msigdb_reactome/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed26f3277144a692d0f2b483eb723b24a38f8ef8cc81099eb6c6809fd9de018a +size 132244 diff --git a/msigdb_reactome/basic/plot_45.png b/msigdb_reactome/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..e261f762b7ec87d28afebe2d7ef011a0a4ec21d4 --- /dev/null +++ b/msigdb_reactome/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:987d5439116dc987c7c15e9cd4c2ef2d30dc83f00877aa1e8d8154325091fecb +size 150105 diff --git a/msigdb_reactome/basic/plot_46.png b/msigdb_reactome/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..0f3e89a7eedd86d650557b86296ffa63cedc3616 --- /dev/null +++ b/msigdb_reactome/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:844a6237f5c2c364965814546ba9e3443e7f7bc9e714a3c14adab6e040935887 +size 134458 diff --git a/msigdb_reactome/basic/plot_47.png b/msigdb_reactome/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..41b1a44fe58ea88312b82647fcf5e4a2e506ff13 --- /dev/null +++ b/msigdb_reactome/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4df631af2f9098d938aedf279a3a0a9acf30278aee09eb8052ccb77f7302a8e1 +size 143902 diff --git a/msigdb_reactome/basic/plot_48.png b/msigdb_reactome/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..c173510ab570faedef9119996ef23b92c422ad2b --- /dev/null +++ b/msigdb_reactome/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50829daf967f84c297a6031d091efd9cdf8a68d676b7e5b5eae4ed4871ec064d +size 136329 diff --git a/msigdb_reactome/basic/plot_49.png b/msigdb_reactome/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..fb09db1c7d240cbe3a339318dc9ca1ccd8a3c4fe --- /dev/null +++ b/msigdb_reactome/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aea614d5bd0976bc4284cedd96badaad0de26a78841fe33f719f3634250e91a9 +size 145814 diff --git a/msigdb_reactome/basic/plot_5.png b/msigdb_reactome/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..46d67d8c7fee216d9b88c9f8fa5085202a50ef57 --- /dev/null +++ b/msigdb_reactome/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e90a6270f60b6aecd0163f59ef0ab9ae0091495bc5a19fd2ad442ef132e96dd +size 137332 diff --git a/msigdb_reactome/basic/plot_6.png b/msigdb_reactome/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..32e61ece2ed08191e5d4f6751e246aa8cb0c8c47 --- /dev/null +++ b/msigdb_reactome/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eeb4dc8c5f57c003f1f5d389a5d1bf1adcbdc28e7782161c5afd75f1fadbd8a3 +size 142744 diff --git a/msigdb_reactome/basic/plot_7.png b/msigdb_reactome/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..2634067a995fbf179407b6672bf15c398d2f73c7 --- /dev/null +++ b/msigdb_reactome/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a8ec1345af941328da4b718e37aac854cee2d156198c5333b9aa6e32adff29d +size 133062 diff --git a/msigdb_reactome/basic/plot_8.png b/msigdb_reactome/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..1de30d77e12f56b7d9e431e5b23241286c053250 --- /dev/null +++ b/msigdb_reactome/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba855292c8638ab2bf436b218261676b19c1cd8b7beef86e5f462c397d5923d0 +size 132252 diff --git a/msigdb_reactome/basic/plot_9.png b/msigdb_reactome/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..d8cb543bd041b68a8d60202faff60230c51f7eda --- /dev/null +++ b/msigdb_reactome/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d254934299165a3ff00e68b26afc8ffc9e0c4cba7dd1fa6ce486927780cea3fb +size 141655 diff --git a/msigdb_reactome/consensus.joblib b/msigdb_reactome/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..13cccddaa6ef4fb9be93eb0c6e6bcb421201098b --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:990819384f6759ecb720e74a6b60a58c3a8238904a61b8b9bbbf2210a33fa94b +size 183828 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..93f5bd68742a8c0a869836b7c1264f1a9a2b816a --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,26 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport of small molecules 35 137 3.586419633672352 0.0003352493204897 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 0.000134572176089 0.001776683555075 0.0002288389739331 0.0018514693185375 3.3294778640996965e-05 +Activation of ampk downstream of nmdars 2 5 2.639105315686044 0.0083125152968723 3.354368932038835 6.451456310679611 0.5566970459139938 0.4440483464816752 1.771033196282823 1.4598419968812493 1.088746190595968 0.3283169353723064 0.0025355024962392 1.0 0.0009803497739799 0.0132372029803992 0.0790607116166092 +Synaptic adhesion like molecules 0 5 2.5437808378327187 0.0109659864832496 1.6674757281553398 5.951456310679611 1.045730316736721 0.2890276876766184 1.4188777313077996 1.1438195320406324 0.8614150619700692 0.2468687149363868 0.1364388664089949 0.0506073598520519 0.0998570540504815 0.2348471946143729 0.4217257773445009 +Deubiquitination 16 82 2.4996662162183827 0.0124310368596818 21.274271844660195 90.48543689320388 0.4172727973060445 0.5987827475213043 11.64961844468234 9.030277095459189 1.0784969503501256 0.3703499256790007 0.1693360503645068 0.085412898243946 0.1591127653551485 0.0026091159714749 0.0406614656106359 +Assembly and cell surface presentation of nmda receptors 5 7 2.491283414838517 0.0127282543337015 4.021844660194175 10.050970873786408 0.6119431771279947 0.4638365400303644 2.466672711798564 1.7830986526204615 1.029606868598912 0.3372268056856337 0.0058378935913216 1.0 0.0023011729003655 0.0042306660622233 0.001918269568256 +Sphingolipid de novo biosynthesis 4 9 2.4047878789211388 0.0161818554383899 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0005399457624048 0.1280604643503683 0.0307863463383066 0.0005695758393465 0.0119362160344991 +Protein localization 26 65 2.3446375689144463 0.0190455830167539 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 2.656795912988199e-06 0.0005165575391543 7.726867136605417e-06 2.771629741540472e-07 7.671538691914916e-10 +Carboxyterminal post translational modifications of tubulin 2 5 2.3282242326888696 0.0199002000785348 3.2111650485436893 5.764563106796117 0.4532219515804401 0.4130550911105556 1.6044754161745491 1.1192952677926271 1.149295682796638 0.3146953714506392 0.0042187298845272 1.0 0.0016492758756177 0.0213395532455881 0.1188827437046941 +The citric acid tca cycle and respiratory electron transport 22 80 2.299063657984422 0.0215013247891353 27.99757281553398 94.17961165048544 0.4883573568636233 0.4259472248586306 12.60942373482268 7.020896123249261 1.7895370613076145 0.38969273744301 0.0002667601605869 0.0066467044558672 0.0008091544089646 0.0004702534061255 2.646923931759353e-06 +Pink1 prkn mediated mitophagy 3 9 2.2969640692126267 0.0216208195294849 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0013474758590725 6.357667188483331e-05 0.0005152543640852 0.0006049883657283 0.0078812527225172 +Transport of inorganic cations anions and amino acids oligopeptides 2 10 2.263644454742345 0.0235959913364778 3.45873786407767 9.99514563106796 1.347451847228265 0.1988162564497566 2.1544143797408783 1.7967002462592632 1.0339867286779445 0.2465647399589519 0.0202509901610398 0.1878492321971458 0.0083373177591013 0.0884797465964613 0.1636366172223574 +Amino acid transport across the plasma membrane 1 5 2.25147757759044 0.0243553054889902 1.6019417475728157 3.9466019417475726 0.6798215426479346 0.3497589750262466 1.2195001827124836 1.03907310581091 1.144086667263588 0.2965730694092905 0.2028965966813109 1.0 0.1500965904253892 0.3388735835116871 0.1985866733922443 +Rho gtpases activate iqgaps 2 9 2.178567028716814 0.0293638477699464 4.924757281553398 10.973300970873789 0.1392446665740701 0.6096259755368159 2.979162045691005 1.3207697728641727 0.9184481670839386 0.3154644259160195 0.004723284297047 1.0 0.0018516158363228 0.0237046415332288 0.1298078118605267 +Mitophagy 3 12 2.1285853200546434 0.0332885841195425 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.003748436319949 0.0001849020150097 0.0014613866465803 0.0023669228385379 0.0269295467729808 +Organelle biogenesis and maintenance 25 79 2.107215342405137 0.0350989176230429 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.0029306763739106 0.0367932036645418 0.0009935643985759 0.0283661385295202 0.0369254089750933 +Gamma carboxylation hypusine formation and arylsulfatase activation 1 8 2.0906152919887693 0.0365625638307995 3.029126213592233 10.00485436893204 0.7807506256376007 0.3924946945170767 1.4628493985065265 1.556376089571428 0.8873758348558936 0.2775880490120545 0.0559891440928278 0.1280604643503683 0.2423974925429197 0.1532325517723639 0.1645088237572309 +Ras processing 3 6 2.088891906045202 0.0367174546100108 1.3519417475728157 4.871359223300971 1.1011688928930974 0.2799307194914149 1.0191949595335985 0.8620674500492106 1.0561018280407846 0.2880746444526379 0.2239007401958742 0.0858288536093336 0.1662183776826317 0.0752233407476578 0.0118865434534573 +Synthesis of pa 3 8 2.0376104295061466 0.0415889081851807 2.9635922330097086 8.558252427184467 0.9129149199765416 0.2964837496518883 1.9473992387004595 1.904008254033093 1.1909456358572703 0.2923824193190221 0.0428038646952677 0.0060764540616979 0.0233124310373507 0.0213395532455881 0.0062616815035888 +Gap junction trafficking and regulation 2 10 2.037066334681612 0.041643394980583 4.633495145631068 11.28640776699029 0.0348608183519093 0.586148089004064 2.81796325564593 1.3583648468018643 0.9454550113075428 0.3181586964978685 0.0058378935913216 1.0 0.0023011729003655 0.0288428745821564 0.1526461610854137 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 3 6 2.012835449302925 0.0441319432339881 2.808252427184466 8.344660194174757 -0.0367658334436417 0.47043079112258 1.6023738016949065 1.4573701647671262 1.0676278865531703 0.3078458831035016 0.2443554045423122 1.0 0.1820374447866984 0.0895680133917324 0.017002584405276 +Post chaperonin tubulin folding pathway 2 8 2.009783412249988 0.0444541171620693 4.631067961165049 9.669902912621358 0.1824952152215168 0.5047249093477747 2.528441291450786 1.207889513967516 1.0855078483623932 0.3264088774408823 0.0016013950645132 1.0 0.0006140521777265 0.0085625102176751 0.0013369974246366 +Cytokine signaling in immune system 29 165 2.006779379534418 0.0447731594342928 40.29368932038835 173.29854368932038 -0.0419239880059683 0.7354133819481531 16.66208005117109 10.373402219489734 0.7729691766579994 0.321411905304117 0.1485838039352038 0.8483649334693243 0.5156149932176817 0.000490359593774 0.000713008924681 +Selective autophagy 7 27 2.000233907165708 0.0454750120557339 7.315533980582524 31.50728155339806 0.9304065525388932 0.4028226131520862 3.350474746292583 3.101431769008479 1.074438805028982 0.3502038092942861 0.0002480615722608 0.0037980660192356 3.96522323168705e-05 0.0001901167909256 0.0153483993146073 +Mitotic g2 g2 m phases 11 77 1.994157964827118 0.0461347942784557 25.512135922330096 89.70388349514563 0.5564324413272281 0.5721896286221594 11.374146646790262 7.343161700072858 1.2377579618165189 0.3831596446417351 0.003258888841079 0.0568182225456719 0.0003818801352559 0.0017587325082107 0.037022484571323 +Mitochondrial calcium ion transport 4 14 1.9644031003668485 0.0494833635901794 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 6.483657403485675e-06 0.0043047615253927 0.0009803497739799 0.0001141854355465 0.0003689915939861 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..91d1e3f19829b730ac7bc85e4d8000fcb67a0b2e --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 1372, + "title": "Average number of proteins per term", + "value": 17.831632653061224 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e12931134f7cfe10f367530fc752759897ce5dd6 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..21f111f84c9208bcf2650ec06d24a822e1a34b19 --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,450 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport of small molecules 0.5006563048416983 3.5864196336723517 0.0003352493204897 0.368741091447466 0.076660344618664 137 P12235,Q70HW3,Q8IYU8,Q01650,P60900,P61289,P21796,P36404,O15118,Q9HD20,Q8NEW0,P45880,Q9BUN8,P20020,Q9Y487,P30519,P28074,Q93050,P28072,P30825,Q9BPX6,Q9UBX3,P53985,Q13555,P16615,Q4KMQ2,Q8TB61,P40855,Q99436,P49721,Q9GZP9,P09601,Q96PU5,P35611,Q9Y277 35 +Gap junction assembly 0.9740121039515844 2.878324060528089 0.00399794218224 0.9958975490685864 0.1870697887820304 3 Q9BVA1,P68371 2 +Transport of connexons to the plasma membrane 0.9740121039515844 2.878324060528089 0.00399794218224 0.9958975490685864 0.1870697887820304 3 Q9BVA1,P68371 2 +Release of apoptotic factors from the mitochondria 0.9320284697508944 2.7109130352639528 0.0067098221938892 0.9999026209827828 0.1870697887820304 2 O60443 1 +Creb phosphorylation 0.9227758007117488 2.673124551158895 0.007514834341864 0.9999679844295992 0.1870697887820304 2 Q15418 1 +Activation of ampk downstream of nmdars 0.91626293790029 2.639105315686044 0.0083125152968723 0.999989376441092 0.1870697887820304 5 Q9BVA1,P68371 2 +Downregulation of erbb2 erbb3 signaling 0.9113879003558706 2.626372399061437 0.0086300342617637 0.9999931536468202 0.1870697887820304 2 P40818 1 +Deubiquitination 0.489073110756455 2.4996662162183827 0.0124310368596818 0.9999999648020296 0.1870697887820304 82 P49721,Q15388,Q96RU2,P28072,Q8TEY7,P28074,P60900,P21796,Q8NB78,Q96K76,Q96FW1,P40818,P45880,Q9NXR7,Q99436,Q9Y277 16 +Assembly and cell surface presentation of nmda receptors 0.8814279767090782 2.491283414838517 0.0127282543337015 0.9999999767103064 0.1870697887820304 7 Q13555,Q9BVA1,Q9BUF5,O14936,P68371 5 +Ras activation upon ca2 influx through nmda receptor 0.8790048652240059 2.4882874718615913 0.0128359930633354 0.9999999799489904 0.1870697887820304 3 Q13555 1 +Long term potentiation 0.8790048652240059 2.4882874718615913 0.0128359930633354 0.9999999799489904 0.1870697887820304 3 Q13555 1 +Unblocking of nmda receptors glutamate binding and activation 0.8790048652240059 2.4882874718615913 0.0128359930633354 0.9999999799489904 0.1870697887820304 3 Q13555 1 +Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8781243273048128 2.484584254378203 0.0129702811333558 0.9999999833630208 0.1870697887820304 3 P67812 1 +Synthesis secretion and deacylation of ghrelin 0.8781243273048128 2.484584254378203 0.0129702811333558 0.9999999833630208 0.1870697887820304 3 P67812 1 +Alpha oxidation of phytanate 0.8784390888334968 2.482734746694347 0.013037813155839 0.9999999848537466 0.1870697887820304 4 P51648 1 +Pre notch processing in golgi 0.8747330960854147 2.474046557508525 0.0133592286069026 0.999999990312145 0.1889573365842312 2 P16615 1 +Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.871199029610491 2.4520856517261187 0.014203084959649 0.9999999970050616 0.1895022369278749 4 P67812 1 +Incretin synthesis secretion and inactivation 0.871199029610491 2.4520856517261187 0.014203084959649 0.9999999970050616 0.1895022369278749 4 P67812 1 +Synthesis of pe 0.8690391459074739 2.4501298298645517 0.0142804713276201 0.9999999973108756 0.1895022369278749 2 Q9Y6K0 1 +Bmal1 clock npas2 activates circadian gene expression 0.8669039145907573 2.4411433123314072 0.0146408433778095 0.9999999983717098 0.1895022369278749 2 P43490 1 +Sphingolipid de novo biosynthesis 0.8608126207586166 2.4047878789211388 0.0161818554383899 0.9999999998098292 0.2000135645177563 9 Q96G23,O95470,O15269,P51648 4 +Myoclonic epilepsy of lafora 0.846619217081858 2.3552874087028632 0.0185083841812219 0.999999999992614 0.2016494082549551 2 P46976 1 +Protein localization 0.6217545047307295 2.3446375689144463 0.0190455830167539 0.9999999999965152 0.2016494082549551 65 Q99595,P50402,P12235,O60830,Q9NS69,P21796,Q8N4H5,O43765,O15228,Q15388,P51648,Q13505,O75874,Q13190,O14925,O15254,P40855,Q9UJS0,P46379,Q9BY49,Q15067,O00116,Q8TB36,P09601,Q5JRX3,Q3ZCQ8 26 +Carboxyterminal post translational modifications of tubulin 0.8429958937932989 2.3282242326888696 0.0199002000785348 0.999999999998946 0.2016494082549551 5 Q9BVA1,P68371 2 +Endosomal vacuolar pathway 0.8397435897435739 2.3176205558744094 0.020469952037379 0.9999999999995254 0.2016494082549551 4 P01889,Q9UIQ6,P10321 3 +Proton coupled monocarboxylate transport 0.8348754448398554 2.3051801988074776 0.0211564833708965 0.9999999999998186 0.2016494082549551 2 P53985 1 +Transport of bile salts and organic acids metal ions and amine compounds 0.8351726593093673 2.3019354909981184 0.0213388103649792 0.9999999999998596 0.2016494082549551 3 Q8NEW0,P53985 2 +The citric acid tca cycle and respiratory electron transport 0.4888189753227682 2.299063657984422 0.0215013247891353 0.9999999999998882 0.2016494082549551 80 O75880,P13073,O43676,O43819,P21796,P03886,P56134,O75964,P00403,P24539,Q9P0J0,P06576,Q13423,P53985,P47985,O96000,Q9UDW1,Q9Y6M9,O14949,O75306,P48735,Q15120 22 +Pink1 prkn mediated mitophagy 0.8363039250040998 2.2969640692126267 0.0216208195294849 0.9999999999999054 0.2016494082549551 9 Q9NS69,Q8N4H5,P21796 3 +Acyl chain remodelling of pg 0.8284697508896904 2.2777248478286887 0.0227429763359152 0.9999999999999803 0.2041037952871139 2 Q8NF37 1 +Transport of inorganic cations anions and amino acids oligopeptides 0.8285025206256671 2.263644454742345 0.0235959913364778 0.999999999999994 0.2075237186772281 10 P30825,Q70HW3 2 +Amino acid transport across the plasma membrane 0.825316673593832 2.25147757759044 0.0243553054889902 0.999999999999998 0.2089796744764246 5 P30825 1 +Wax and plasmalogen biosynthesis 0.8227668101473466 2.244163984478124 0.02482185237144 0.9999999999999988 0.2089796744764246 4 O00116 1 +Formation of fibrin clot clotting cascade 0.8167259786476946 2.2271625239981767 0.0259364137633426 0.9999999999999998 0.2089796744764246 2 P42785 1 +Intrinsic pathway of fibrin clot formation 0.8167259786476946 2.2271625239981767 0.0259364137633426 0.9999999999999998 0.2089796744764246 2 P42785 1 +Tysnd1 cleaves peroxisomal proteins 0.8174029808958286 2.220826409716373 0.0263627210959653 1.0 0.2089796744764246 4 O00116 1 +Notch3 activation and transmission of signal to the nucleus 0.8118195664368557 2.200969956688141 0.0277381507735308 1.0 0.2160201320007926 3 P67809 1 +Cytochrome p450 arranged by substrate type 0.8068396286752937 2.1792886004171095 0.0293102355370296 1.0 0.2160201320007926 3 Q16850 1 +Rho gtpases activate iqgaps 0.8097333243237324 2.178567028716814 0.0293638477699464 1.0 0.2160201320007926 9 Q9BVA1,P68371 2 +Platelet calcium homeostasis 0.8055991178700324 2.173879506238528 0.0297141855161813 1.0 0.2160201320007926 3 P16615 1 +Reduction of cytosolic ca levels 0.8055991178700324 2.173879506238528 0.0297141855161813 1.0 0.2160201320007926 3 P16615 1 +Regulation of ifng signaling 0.8047163303985334 2.16538210141165 0.0303584355937307 1.0 0.2160201320007926 4 P15260 1 +Synthesis of pips at the er membrane 0.8021352313167287 2.1639332983563206 0.0304694689325912 1.0 0.2160201320007926 2 Q9NTJ5 1 +Mapk3 erk1 activation 0.8032569034729846 2.1636576272397745 0.0304906352645699 1.0 0.2160201320007926 3 Q06124 1 +Flt3 signaling 0.8042155771478907 2.163186593591792 0.0305268309743838 1.0 0.2160201320007926 4 Q06124 1 +Mitophagy 0.7978523084978081 2.1285853200546434 0.0332885841195425 1.0 0.2222940159140184 12 Q9NS69,Q8N4H5,P21796 3 +Organelle biogenesis and maintenance 0.4787782146226064 2.107215342405137 0.0350989176230429 1.0 0.2293129284705473 79 A6NIH7,Q9NX63,O43924,P48643,P36542,P56134,O75964,O95684,O94927,Q13561,Q9BW83,Q9NVH1,P68371,Q7Z4L5,P24539,P06576,P07437,Q9BVA1,Q13505,Q9BUF5,Q6UXV4,O75935,P48735,Q86X55,Q9Y512 25 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.7901629332972789 2.0906152919887693 0.0365625638307995 1.0 0.2343085940694646 8 O60725 1 +Ras processing 0.7892694729001412 2.088891906045202 0.0367174546100108 1.0 0.2343085940694646 6 O43924,O60725,P49356 3 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.783575335404309 2.0722265177720907 0.0382443215137895 1.0 0.235296901869593 4 P12235,P36404 2 +Regulation of ifna signaling 0.780559116662123 2.06399713587392 0.0390179879484637 1.0 0.2389851761843407 3 Q06124 1 +Vegfr2 mediated cell proliferation 0.7772072905473613 2.0491880170198 0.0404437333638301 1.0 0.2454877537054899 3 O43865 1 +Synthesis of pa 0.7784274229400501 2.0376104295061466 0.0415889081851807 1.0 0.2466317919295756 8 Q9NPH0,Q8NF37,Q8N2A8 3 +Gap junction trafficking and regulation 0.7784106881428898 2.0370663346816116 0.041643394980583 1.0 0.2466317919295756 10 Q9BVA1,P68371 2 +Tp53 regulates transcription of cell death genes 0.7755527822506081 2.0366283517482047 0.041687299403619 1.0 0.2466317919295756 4 Q92696 1 +Rsk activation 0.7727214751375807 2.02933191311133 0.0424244949155825 1.0 0.2480910274194532 3 Q15418 1 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.7722801866478215 2.0128354493029255 0.0441319432339881 1.0 0.2490026743751812 6 Q13555,P51812,Q15418 3 +Post chaperonin tubulin folding pathway 0.7722924033059216 2.0097834122499876 0.0444541171620693 1.0 0.2490026743751812 8 Q9BVA1,P68371 2 +Cytokine signaling in immune system 0.3753122746587403 2.006779379534418 0.0447731594342928 1.0 0.2490026743751812 165 P04083,P60900,P08670,P01889,P52597,P10321,P30154,P28074,O14979,Q8NFH4,P28072,Q13555,Q06124,P15260,Q9Y3Z3,Q15418,Q8N1F7,P51812,Q99436,P51809,P49721,Q9BTX1,Q07820,P09601,Q13126,P55735,Q15369,P31751,Q53EL6 29 +Nicotinamide salvaging 0.7675226403431429 2.0062672619001174 0.0448277409407213 1.0 0.2490026743751812 3 P43490 1 +Selective autophagy 0.7511491402568873 2.0002339071657076 0.0454750120557339 1.0 0.2505691427327988 27 Q9NS69,Q9BVA1,Q9BUF5,P21796,P68371,Q8N4H5,P08670 7 +Mitotic g2 g2 m phases 0.4844856314345734 1.994157964827118 0.0461347942784557 1.0 0.2531877510001654 77 P49721,P07437,O95684,Q9BVA1,P28074,O94927,Q9BUF5,P60900,P68371,O95067,P28072 11 +Mitochondrial calcium ion transport 0.7615919006008598 1.9644031003668485 0.0494833635901794 1.0 0.2659360539527495 14 P45880,Q9BPX6,P21796,Q9Y277 4 +Mitotic prometaphase 0.4266129078227991 1.9326369502583405 0.0532809372165423 1.0 0.276554409013397 83 P07437,O95684,Q9BVA1,O94927,Q9BUF5,Q7L7X3,P55735,P68371,Q15005,Q8NFH4,O95067,O75935 12 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7540199949585553 1.9247613658483345 0.0542592193682329 1.0 0.2798633420045701 10 P50402,P51648,Q13190,P09601,P46379 5 +Signaling by interleukins 0.3957996182470959 1.9127697204108964 0.0557775391303307 1.0 0.2807076667675931 99 P04083,P60900,P61289,P08670,P52597,P30154,P28074,O14979,P28072,Q06124,Q15418,P51812,Q99436,P51809,P49721,Q02750,Q07820,P09601,Q13126,Q53EL6 20 +Ctla4 inhibitory signaling 0.7475843177726342 1.9061019504794192 0.0566369797057744 1.0 0.2807076667675931 5 P31751,Q06124 2 +Gastrin creb signalling pathway via pkc and mapk 0.746276778542967 1.905589070637469 0.056703541231091 1.0 0.2807076667675931 4 Q15418 1 +Constitutive signaling by akt1 e17k in cancer 0.7434163701067784 1.9049563692518243 0.0567857428657923 1.0 0.2807076667675931 2 P31751 1 +Cd28 dependent pi3k akt signaling 0.7434163701067784 1.9049563692518243 0.0567857428657923 1.0 0.2807076667675931 2 P31751 1 +Aggrephagy 0.7452664175812429 1.8844027106519512 0.0595105234675574 1.0 0.2874945006953833 12 Q9BVA1,Q9BUF5,P68371 3 +Formation of tubulin folding intermediates by cct tric 0.7418599088654704 1.868042726121804 0.0617561157141546 1.0 0.2929584641623646 11 Q9BVA1,P68371 2 +Ptk6 regulates proteins involved in rna processing 0.7365610537557932 1.867760273742331 0.0617954930578203 1.0 0.2929584641623646 3 Q07666,O75525 2 +Class b 2 secretin family receptors 0.7284697508896805 1.837914203016504 0.0660750488868981 1.0 0.3021832235760811 2 Q9Y3E5 1 +Intraflagellar transport 0.7347810804909767 1.8352964596876948 0.066461775359534 1.0 0.3029420458248527 10 Q9BVA1,Q9BUF5,P68371,Q7Z4L5 4 +Thromboxane signalling through tp receptor 0.7287290850836636 1.832420289882995 0.0668888274303634 1.0 0.3037370847018595 3 Q13685,Q14344 2 +Signaling by receptor tyrosine kinases 0.386842518781664 1.8244320822188196 0.0680867754753289 1.0 0.3062788719742665 105 Q06124,Q9UQB8,Q93050,P51812,P31751,P31943,Q15418,Q7L576,O43865,P40818,Q96J02,Q14155,P04792,Q9Y487,P52597 15 +Activation of nmda receptors and postsynaptic events 0.723702943908891 1.79889976502698 0.0720345377818592 1.0 0.3179126954764267 19 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,Q14155,P51812 8 +Heme degradation 0.7236331727465259 1.797169298561181 0.0723087469278507 1.0 0.3179126954764267 5 P30519 1 +Nod1 2 signaling pathway 0.7197427248857189 1.7853342544311486 0.0742071158305797 1.0 0.3211740155191021 4 Q15750,Q96J02 2 +Ros and rns production in phagocytes 0.7178447499421916 1.7573792967910584 0.0788531797684366 1.0 0.3349827599279261 9 Q9Y487 1 +Synthesis of pc 0.7159804403477128 1.7565515192472645 0.0789942826718761 1.0 0.3349827599279261 6 Q9Y6K0,Q8NF37 2 +Mapk family signaling cascades 0.4426403159157932 1.7401920071664942 0.0818253086396554 1.0 0.3365880733441354 79 P49721,Q13555,Q02750,Q06124,O60725,P30154,P28074,P60900,P61289,O43924,Q14168,P28072,P04792,Q99436,P30086,P49356 16 +G alpha q signalling events 0.712714282632678 1.73822578618464 0.0821710371713184 1.0 0.3365880733441354 7 P04083,Q15418 2 +Apoptotic factor mediated response 0.7085097436777954 1.734019369724483 0.0829146464222509 1.0 0.3385681395575249 4 O60443 1 +Ub specific processing proteases 0.516053902025914 1.7290141917263415 0.0838065551527578 1.0 0.3386007791531075 69 P49721,Q15388,P28072,Q8TEY7,P60900,P28074,P21796,Q96K76,P40818,P45880,Q9Y277 11 +Caspase mediated cleavage of cytoskeletal proteins 0.7072807647038466 1.722163291464944 0.0850399425072729 1.0 0.3421548419940719 5 P08670 1 +Post translational modification synthesis of gpi anchored proteins 0.7040270651910934 1.7013457393451417 0.0888780838362715 1.0 0.3514142104419726 6 Q9ULX3 1 +Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0.6972718930892445 1.6893075502980248 0.0911605072165349 1.0 0.3524852957988849 3 P17931 1 +Mitotic metaphase and anaphase 0.3628808192768809 1.6839155983139318 0.0921979813582731 1.0 0.3524852957988849 135 P50402,P60900,Q7L7X3,Q86XL3,O95067,Q96DE5,P30154,P28074,P68371,Q8NFH4,P42167,P28072,Q9BVA1,P42166,Q9BUF5,Q15005,Q8N1F7,Q99436,P49721,Q9BTX1,P55735 21 +Insulin receptor recycling 0.7006428042158257 1.6747418191509815 0.093984898553264 1.0 0.3524852957988849 10 Q9Y487 1 +Mitochondrial protein import 0.6792666545692857 1.6668124091870848 0.0955517119692206 1.0 0.3524852957988849 31 Q99595,Q9NS69,O60830,Q15388,Q13505,O14925,P21796,Q5JRX3,Q8N4H5 9 +Interferon gamma signaling 0.6983646190051558 1.661526001546365 0.0966078512443961 1.0 0.3524852957988849 13 Q13555,Q06124,P04439,P15260,P18031,P01889,P10321 7 +Shc related events triggered by igf1r 0.687544483985765 1.6521911098015425 0.0984955981929587 1.0 0.3541745198495939 2 P08069 1 +Dap12 interactions 0.6919975711370332 1.6516237614728866 0.0986112730193475 1.0 0.3541745198495939 5 P01889 1 +Transport of vitamins nucleosides and related molecules 0.6937023644599517 1.6497284418013214 0.0989984902692033 1.0 0.3546046493305255 7 P12235,P36404,Q8TB61 3 +Class i mhc mediated antigen processing presentation 0.3728533038057317 1.637066024098854 0.1016166747912041 1.0 0.3593274956215536 104 Q6P179,P52888,P60900,P61289,Q9UIQ6,P01889,O00231,P10321,P53992,P55786,P28074,Q9NZ08,P28072,P04439,Q99436,P27824,P49721,Q9UJX4,O95376,Q9UJX6,P55735,Q15369,Q96PU5,Q96J02 24 +Recruitment of numa to mitotic centrosomes 0.6778472230542713 1.6175006622710608 0.1057702528383837 1.0 0.3595172156691956 27 P07437,O95684,Q9BVA1,O94927,Q9BUF5,P68371 6 +Phase i functionalization of compounds 0.6880321756348325 1.61171885999109 0.1070231316999481 1.0 0.359891511500806 14 O43169,Q16850,P07099,P16435 4 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6768683274021527 1.6032605853937008 0.1088771344851977 1.0 0.3634535973569132 2 P11802 1 +Ptk6 regulates cell cycle 0.6768683274021527 1.6032605853937008 0.1088771344851977 1.0 0.3634535973569132 2 P11802 1 +Activated tak1 mediates p38 mapk activation 0.6743772241992966 1.591817158373985 0.1114257936378089 1.0 0.3692661566934473 2 Q15750 1 +Adp signalling through p2y purinoceptor 1 0.6743772241992873 1.5918171583739416 0.1114257936378186 1.0 0.3692661566934473 2 P63218 1 +Peroxisomal lipid metabolism 0.6814898279828815 1.5819041149363988 0.1136714614246878 1.0 0.3728201596964312 11 Q9BY49,O15254,P51648 3 +Heme signaling 0.6753537223313677 1.5812559691525858 0.1138195227584173 1.0 0.3728201596964312 4 P09601 1 +Irs mediated signalling 0.6736642807589515 1.5734236985826116 0.1156207431424563 1.0 0.3759044066148105 4 Q06124 1 +Striated muscle contraction 0.6746927781815446 1.5712782489129498 0.1161180312657208 1.0 0.3760189923092032 5 P08670,P09493,P67936 3 +Pregnenolone biosynthesis 0.6734064746187063 1.5652870582383858 0.1175156162821728 1.0 0.3784775247397681 5 O95772 1 +Interferon alpha beta signaling 0.6677436814147432 1.5180511965561014 0.1290014928232494 1.0 0.3988652085640712 10 P04439,Q06124,Q9Y3Z3,P01889,P10321 5 +Attachment of gpi anchor to upar 0.6611203054521458 1.5151368493364803 0.1297377515055859 1.0 0.3988652085640712 4 Q92643,O43292 2 +Glycerophospholipid biosynthesis 0.6582002562067204 1.5129364839594468 0.1302957934340116 1.0 0.3988652085640712 27 Q92604,Q8N2A8,Q8NCC3,Q96N66,Q9NPH0,Q8NF37,P35790,Q99829,Q9Y6K0,Q9BZF1,O15228,Q99943 12 +Adaptive immune system 0.3440720206297325 1.51035853752622 0.1309519623893797 1.0 0.3988652085640712 169 P52888,P60900,P61289,Q9UIQ6,O43865,P01889,P10321,P53992,P55786,P30154,P28074,P68371,P28072,Q9NZ08,Q9BVA1,Q06124,Q9BUF5,O75935,Q99436,P49721,Q9UJX4,P55735,Q15369,Q96PU5,Q96J02,P31751 26 +M phase 0.3430738670148191 1.5052539658970667 0.1322587954765961 1.0 0.3996895757574667 183 P50402,P60900,Q01105,Q7L7X3,Q86XL3,O95067,Q96DE5,O95684,P30154,P28074,O94927,P68371,Q8NFH4,P42167,P28072,P07437,Q9BVA1,P42166,Q9BUF5,Q9Y6X3,Q15005,Q8N1F7,O75935,Q99436,P49721,Q9BTX1,Q9UJX4,P55735 28 +Dag and ip3 signaling 0.66048537209241 1.4936694677265805 0.1352620325984546 1.0 0.4053270801175502 7 O43865 1 +Peptide ligand binding receptors 0.6588459776537995 1.4904985794620682 0.1360931897028532 1.0 0.4053270801175502 6 Q9BYT8,P04083,Q9NZJ7 3 +Class a 1 rhodopsin like receptors 0.6588459776537995 1.4904985794620682 0.1360931897028532 1.0 0.4053270801175502 6 Q9BYT8,P04083,Q9NZJ7 3 +Platelet sensitization by ldl 0.6573279201820244 1.4901944201092818 0.1361731231244562 1.0 0.4053270801175502 5 Q06124 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.6625508241905855 1.487218489549867 0.1369571142524748 1.0 0.4053270801175502 14 P53992,P04439,P55735,Q9NZ08,P01889,P27824,P10321 7 +Platelet homeostasis 0.6590734437850809 1.479449007370052 0.1390203503684346 1.0 0.4074857325363311 9 P16615,Q06124,P30154 3 +Tp53 regulates transcription of death receptors and ligands 0.6492971117116253 1.467834458160189 0.142149194999078 1.0 0.4137228389893145 3 P49327 1 +Flt3 signaling in disease 0.6499715033193398 1.4631493094199182 0.1434265277681219 1.0 0.4151502027381082 4 Q06124 1 +Kinesins 0.6571478297439488 1.460869615403223 0.1440512265404714 1.0 0.4155538910424847 16 Q9BVA1,P68371 2 +Antigen processing ubiquitination proteasome degradation 0.3762660185073315 1.4521275909834803 0.1464661314645703 1.0 0.4169118928825529 84 P49721,Q9UJX4,P55786,P52888,P28074,P60900,Q9UIQ6,Q15369,Q96PU5,Q96J02,P28072,Q99436 12 +Regulation of tp53 expression and degradation 0.6516191312299816 1.4438201534328814 0.1487895714444769 1.0 0.4212158108452745 9 P30154,P24941,P06493,P42345,P31751,O96017 6 +Cooperation of prefoldin and tric cct in actin and tubulin folding 0.6522648446660023 1.4365789183653042 0.1508376773630764 1.0 0.4222397924108717 16 Q9BVA1,P68371 2 +Nrif signals cell death from the nucleus 0.6405693950177906 1.4356299039538032 0.1511076808117624 1.0 0.4222397924108717 2 Q13501 1 +Nr1h2 and nr1h3 mediated signaling 0.6388684743362318 1.40356434512232 0.1604486186807219 1.0 0.438630458105068 5 Q8NB78 1 +Negative regulation of met activity 0.641695801102771 1.400235180485321 0.1614429041048179 1.0 0.4403571857491258 8 P18031,P40818 2 +Aurka activation by tpx2 0.6372736818775172 1.3774081295568534 0.1683861008515266 1.0 0.4498459205537315 23 P07437,O95684,O94927,P68371 4 +Slc mediated transmembrane transport 0.6381750823144272 1.3744393633220164 0.1693053228272476 1.0 0.4501684165096585 21 P12235,Q70HW3,Q01650,P36404,Q8NEW0,Q8TB61,P30825,Q9UBX3,P53985 9 +Autophagy 0.6015354049503536 1.3511900392822795 0.1766345645117988 1.0 0.4598531736436205 40 Q9NS69,Q9BVA1,Q9BUF5,P21796,P68371,Q8N4H5,P08670 7 +Metabolism of lipids 0.3331927067025068 1.3326948115189243 0.1826319766418154 1.0 0.4736693231617594 156 Q9P035,Q9Y217,Q9NZJ7,Q9NPH0,Q06136,Q8N8N7,P23786,Q709F0,Q9BWD1,Q15392,P30536,Q9BZF3,O15269,Q8N2A8,P53992,Q8NF37,Q9H7Z7,Q9NZ01,Q16850,P51648,Q96N66,O95772,Q9NTJ5,O15254,Q99829,P48449,Q9BY49,Q15067,O00116,P53396,O43772,O95470,Q15800,P35790,Q86X55,Q9Y6K0,Q96G23,Q14534,Q99943 39 +Iron uptake and transport 0.6306168798660955 1.3294894236434052 0.1836865528312876 1.0 0.4746100762420464 18 P30519,P09601,Q9Y487 3 +Sealing of the nuclear envelope ne by escrt iii 0.62823520465078 1.3246369663111996 0.1852915889744033 1.0 0.4764887092324821 11 Q9BVA1,P68371 2 +Heparan sulfate heparin hs gag metabolism 0.620781441779976 1.3183344113113404 0.1873917263854805 1.0 0.4787736473014511 5 P08236,Q7LGA3 2 +O linked glycosylation of mucins 0.6155699451972139 1.3018568572249156 0.1929653230265287 1.0 0.4864557576648102 4 Q10472,O43505 2 +O linked glycosylation 0.6155699451972139 1.3018568572249156 0.1929653230265287 1.0 0.4864557576648102 4 Q10472,O43505 2 +Downregulation of erbb2 signaling 0.6188776708154247 1.3017103932155034 0.1930154053476138 1.0 0.4864557576648102 6 P40818 1 +Separation of sister chromatids 0.3481632042320377 1.3000333585210753 0.1935895362135469 1.0 0.4864557576648102 100 P28070,P60900,P61289,Q7L7X3,Q9BZD4,P57740,O00231,O43684,Q96DE5,Q9UJX3,P30154,P28074,P68371,Q8NFH4,P28072,O60216,Q9BVA1,Q9HBM1,Q9BUF5,Q15005,P49454,Q99436,P49721,Q9UJX4,Q9BW27,Q9UJX6,P55735,Q12769 28 +Signaling by insulin receptor 0.6237355265749966 1.2947274966886235 0.1954142509705527 1.0 0.4901432400943297 15 Q93050,Q06124,Q9Y487 3 +Gpcr ligand binding 0.6175577333172011 1.2848185251365096 0.1988557072408392 1.0 0.4942573013304917 8 P04083,Q9NZJ7,P42892,P07602,Q9Y3E5,Q9BYT8 6 +P75 ntr receptor mediated signalling 0.6180470919022568 1.272097296177014 0.2033385517510364 1.0 0.5007012290238381 12 Q9NQC3 1 +Notch4 activation and transmission of signal to the nucleus 0.6046263345195677 1.268182482735257 0.2047327911679104 1.0 0.5007012290238381 2 Q92542 1 +G alpha 12 13 signalling events 0.6079123430944235 1.257541575552653 0.2085575940929511 1.0 0.5062056867944988 5 Q14155,Q14344 2 +Signalling to ras 0.5931601782831271 1.2052605657798094 0.2281027278241185 1.0 0.5313360654918348 3 P62993 1 +Raf independent mapk1 3 activation 0.5924904426240313 1.1931768371184626 0.2328001241162876 1.0 0.5345229516520658 4 Q06124 1 +Negative regulation of nmda receptor mediated neuronal transmission 0.5920312258889604 1.1910128254439658 0.2336485499914111 1.0 0.5345229516520658 4 Q13555 1 +Complex i biogenesis 0.6008507003728686 1.1814651494213562 0.2374179901924855 1.0 0.5384090620563474 21 P03886,Q9Y6M9,O43676 3 +Caspase activation via extrinsic apoptotic signalling pathway 0.5822935929438969 1.1542515210550184 0.2483970655422198 1.0 0.5508948620614814 3 P49327 1 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5839844339520434 1.1443508953709545 0.2524781439940056 1.0 0.5569132050800252 5 P01889,P10321 2 +Recruitment of mitotic centrosome proteins and complexes 0.5911443685514803 1.1424053415350248 0.2532855720036782 1.0 0.5575598353774053 25 P07437,O95684,O94927,P68371 4 +Metabolism of steroid hormones 0.5856272225970953 1.1375056352691442 0.2553269701659424 1.0 0.5595984074563466 7 O95772 1 +Cristae formation 0.5908016888283201 1.127426674650757 0.2595621262831999 1.0 0.5661673088403026 18 O75964,Q13505,Q9NX63,P24539,Q9NVH1,P06576,P36542,P56134,Q6UXV4,Q9Y512 10 +Anchoring of the basal body to the plasma membrane 0.5886751561184502 1.125581207493744 0.2603428262003171 1.0 0.5664142969287933 24 P07437,O95684,O94927,P68371 4 +Pyruvate metabolism 0.5861482164885113 1.1158021064617731 0.2645068519432469 1.0 0.5675118578128606 12 Q15120,P21796,P53985 3 +Nicotinate metabolism 0.5759704751510565 1.1153353099310437 0.2647067595605961 1.0 0.5675118578128606 4 P43490 1 +The role of gtse1 in g2 m progression after g2 checkpoint 0.5458202385420261 1.1143361787552106 0.265134991672534 1.0 0.5675118578128606 46 P49721,Q9BVA1,P60900,P28074,Q9BUF5,P68371,O95067 7 +P38mapk events 0.5704626334519523 1.1084620778716816 0.267662307954253 1.0 0.5685582151300577 2 Q16539 1 +Formation of atp by chemiosmotic coupling 0.5818586113413629 1.108152482250912 0.2677959684714488 1.0 0.5685582151300577 9 O75964,P24539,P06576,P36542,P56134 5 +Signaling by fgfr4 in disease 0.5697508896797154 1.1051359559738154 0.2691006825875686 1.0 0.5685582151300577 2 P62993 1 +Transferrin endocytosis and recycling 0.583040433788956 1.1045005701147703 0.2693760563800937 1.0 0.5685582151300577 11 Q9Y487 1 +Regulation of signaling by cbl 0.5693950177935945 1.1034729822513365 0.2698218181720386 1.0 0.5685582151300577 2 P62993 1 +Erythropoietin activates ras 0.5693950177935945 1.1034729822513365 0.2698218181720386 1.0 0.5685582151300577 2 P62993 1 +Processing of smdt1 0.580712166443158 1.1026263268408212 0.2701894724962081 1.0 0.5685582151300577 9 Q9BPX6 1 +Signaling by ntrk3 trkc 0.5699537201851153 1.096348382405696 0.2729263437137168 1.0 0.5701731210426315 3 Q8WX92,P62993 2 +Signaling by erythropoietin 0.5695977216091095 1.0946787869459411 0.2736573852650446 1.0 0.5706047607654121 3 P19174,P62993 2 +Hedgehog off state 0.541549227715844 1.0868548160606444 0.2771009776873163 1.0 0.5751626949878942 46 P49721,Q9BVA1,P60900,P28074,Q9BUF5,P68371,Q7Z4L5,P28072 8 +Signaling by gpcr 0.5674539527371145 1.072461941025055 0.2835125995841894 1.0 0.583177341273625 34 P04083,P30154,Q9NZJ7,P31751,Q15418,O43865,Q9BYT8,Q14155,P51812 9 +Glycogen storage diseases 0.5641876375447714 1.069315194745213 0.2849276660997821 1.0 0.5845296447514331 3 P46976 1 +Cyclin a b1 b2 associated events during g2 m transition 0.5732921692154754 1.0668760299471618 0.2860278201861796 1.0 0.5853987341701474 9 O95067 1 +Phospholipid metabolism 0.5560279102353054 1.0625647081770373 0.2879793987226866 1.0 0.5853987341701474 39 Q9Y217,Q9NPH0,Q10713,O15228,Q8N2A8,Q8NCC3,Q8NF37,P42356,P43304,Q9BZF1,Q96N66,Q9NTJ5,Q99829,O96017,Q92604,P35790,Q53H12,Q9Y6K0,Q99943 19 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5127903366231082 1.0536620099357263 0.2920376879246982 1.0 0.5888793004872509 53 O75880,P13073,O43676,O43819,P03886,P36542,P56134,P00403,O75964,P24539,Q9P0J0,P06576,P56385,P47985,O96000,P21912,Q9UDW1,P15954,Q9Y6M9,O95168,O14949,O75306,Q9Y375 23 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5660696844642892 1.0509837719210773 0.2932660431596221 1.0 0.5888793004872509 6 Q06124 1 +Activation of puma and translocation to mitochondria 0.5580071174377146 1.0502977798696107 0.2935812256073467 1.0 0.5888793004872509 2 Q13625 1 +Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.5580071174377146 1.0502977798696107 0.2935812256073467 1.0 0.5888793004872509 2 P24941 1 +Tp53 regulates transcription of genes involved in cytochrome c release 0.5580071174377146 1.0502977798696107 0.2935812256073467 1.0 0.5888793004872509 2 Q13625 1 +Interleukin 4 and interleukin 13 signaling 0.5703764862406571 1.0385864490057857 0.298997110728803 1.0 0.5922331311489425 12 P08670,P04083,P09601 3 +Peptide hormone metabolism 0.5684786894036977 1.0384186316605113 0.2990751990915901 1.0 0.5922331311489425 10 P67812,Q15005 2 +Sulfur amino acid metabolism 0.567026420683558 1.0367160546398169 0.2998682075893777 1.0 0.5922331311489425 9 Q9UBX3 1 +Ion homeostasis 0.5675432107083607 1.0338943325071135 0.3011855648219494 1.0 0.5922331311489425 10 Q13555,O43865,P16615,P20020 4 +Cardiac conduction 0.5675432107083607 1.0338943325071135 0.3011855648219494 1.0 0.5922331311489425 10 Q13555,O43865,P16615,P20020 4 +Regulation of plk1 activity at g2 m transition 0.5673683914139657 1.0336572027723128 0.3012964471880188 1.0 0.5922331311489425 29 O95684,P07437,O94927,P68371,O95067 5 +Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5634601440059036 1.0317992752544014 0.3021661588701696 1.0 0.5930929470241384 7 P09601,Q15750,Q96J02 3 +Maturation of sars cov 2 nucleoprotein 0.5553577785688817 1.0279664451220225 0.3039656119962584 1.0 0.5957725995126664 3 Q96SB4,Q99873 2 +Metabolism of porphyrins 0.5641101083324279 1.0172979631911003 0.3090117052593006 1.0 0.6022216755905689 10 Q7KZN9,P09601,P30519 3 +Signaling by erbb2 0.5611747902356439 1.0085820343954897 0.3131751269453779 1.0 0.6077457909039018 9 P40818 1 +Signaling by hedgehog 0.5125580584793225 1.0023881067538531 0.3161561839907616 1.0 0.6100791623562939 51 P49721,Q9BVA1,P60900,P28074,Q9BUF5,Q9GZP9,P68371,Q7Z4L5,Q96J02,P28072,Q99436 11 +Ion transport by p type atpases 0.5608028545216023 1.001321971148465 0.3166711740995214 1.0 0.6102146781805384 10 Q13555,Q9HD20,P16615,P20020 4 +Neurotransmitter receptors and postsynaptic signal transmission 0.5601172061463271 0.9997481393491688 0.3174324090203524 1.0 0.6104380190612898 30 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,Q14155,P51812 8 +Cholesterol biosynthesis 0.5618226945826392 0.9893024508222704 0.3225151853228001 1.0 0.617142028260644 14 Q16850,Q15800,P48449,Q9BWD1,Q15392,Q14534 6 +Translocation of slc2a4 glut4 to the plasma membrane 0.5567890499924588 0.9813668977307118 0.3264118439167633 1.0 0.6208076113685395 30 P68371,Q9BVA1,Q9UIQ6 3 +Cilium assembly 0.5159849354206049 0.9807962695990048 0.3266932182274675 1.0 0.6208076113685395 49 O95684,P07437,Q9BVA1,O94927,A6NIH7,Q9BUF5,O43924,P68371,Q7Z4L5,O75935 10 +Nuclear envelope ne reassembly 0.5123630549151373 0.9782615476518594 0.3279449827082281 1.0 0.6223243655265408 50 P50402,Q9BVA1,Q9BTX1,P42166,Q9BUF5,P55735,P68371,Q8NFH4,P42167,O95067,Q86XL3 11 +Ion channel transport 0.5568569608101938 0.9666938584085352 0.3336970982347347 1.0 0.6246008441719727 27 Q13555,P16615,Q93050,Q9HD20,Q4KMQ2,Q96PU5,Q9Y487 7 +Erk mapk targets 0.5507809170770595 0.9587125355841682 0.3377035816208318 1.0 0.6286693541163925 9 P51812,Q15418 2 +Mapk targets nuclear events mediated by map kinases 0.5507809170770595 0.9587125355841682 0.3377035816208318 1.0 0.6286693541163925 9 P51812,Q15418 2 +Neuronal system 0.5179594884826494 0.9536253437280332 0.3402733223608116 1.0 0.6308851328095049 47 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,P21964,O95197,Q14155,P51812 10 +Insulin receptor signalling cascade 0.542484362395619 0.9485671929942175 0.3428407832730951 1.0 0.6339320143540248 5 Q06124 1 +Adrenaline noradrenaline inhibits insulin secretion 0.5323843416370012 0.93115410688925 0.3517738535452994 1.0 0.6405463669005022 2 P63218 1 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.5339978640085428 0.9283312214573975 0.3532357835096316 1.0 0.6405463669005022 3 O14734,P51659 2 +Stimuli sensing channels 0.5431009995028495 0.928326877627692 0.3532380360702345 1.0 0.6405463669005022 8 Q9C0H2,Q9H4A3,Q96PU5,Q4KMQ2,Q12797 5 +Mrna decay by 3 to 5 exoribonuclease 0.5500521383423549 0.9279741263429354 0.3534209910668222 1.0 0.6405463669005022 15 Q96B26,Q9NQT4,Q6PGP7,Q969T7 4 +Transmission across chemical synapses 0.5368030324611952 0.9250058773039044 0.3549628502706108 1.0 0.642492124764219 37 Q13555,Q9BVA1,Q9BUF5,Q15418,O14936,P68371,P21964,Q14155,P51812 9 +Cd163 mediating an anti inflammatory response 0.5306049822064066 0.9229187597524442 0.3560495435426141 1.0 0.6433687552301881 2 Q16539 1 +Protein protein interactions at synapses 0.5462202948667859 0.9164007400539496 0.3594567473229082 1.0 0.6463625915164222 13 O14936,O95197 2 +Transcriptional regulation by mecp2 0.5450814072217314 0.9108410593093014 0.3623791249677612 1.0 0.6483975920157053 13 Q13555,Q92769,P18031,P42858,Q13451 5 +Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.5277580071174375 0.9097555868463562 0.3629514217697243 1.0 0.6483975920157053 2 P06493 1 +Sema4d induced cell migration and growth cone collapse 0.5309829059829182 0.9043589907966838 0.3658050760121636 1.0 0.650879925674798 4 P35580,Q13464,P60660 3 +Epha mediated growth cone collapse 0.5309829059829182 0.9043589907966838 0.3658050760121636 1.0 0.650879925674798 4 P35580,Q13464,P60660 3 +Mitochondrial biogenesis 0.5423958967199345 0.9020636193658008 0.3670230733091248 1.0 0.650879925674798 30 O75964,Q13505,Q9NX63,P24539,Q9NVH1,P48735,P06576,P36542,P56134,Q6UXV4,Q9Y512,Q86X55 12 +Ethanol oxidation 0.5280792084080633 0.9008618722707948 0.3676617655961869 1.0 0.650879925674798 3 P30837 1 +Hs gag degradation 0.5262396510186842 0.8923396968039493 0.3722108829010875 1.0 0.65546615310992 3 P08236 1 +Met activates pi3k akt signaling 0.5238434163701092 0.8916849486256467 0.3725618232815733 1.0 0.65546615310992 2 P62993 1 +Death receptor signalling 0.5411403976184272 0.8808851735449067 0.3783799730862833 1.0 0.6621649529009959 16 Q9NQC3,P49327,Q92769,Q14155 4 +Met receptor recycling 0.5242165242165332 0.872910436307392 0.3827118973881789 1.0 0.6651699663999855 4 P20338,P46109,P62993 3 +Mecp2 regulates neuronal receptors and channels 0.5296533801367292 0.871679294478627 0.3833833589687425 1.0 0.6651699663999855 7 Q92769,Q13451 2 +Peroxisomal protein import 0.5397850649622296 0.8715400463725961 0.3834593499158263 1.0 0.6651699663999855 17 Q9BY49,Q15067,O00116,O75874,O15254 5 +Interaction between l1 and ankyrins 0.5215379138483449 0.8705943807535694 0.3839756657352509 1.0 0.6651699663999855 3 Q13813,Q12955 2 +Signaling by flt3 fusion proteins 0.5215379138483379 0.8705943807535369 0.3839756657352686 1.0 0.6651699663999855 3 Q14789,P62993 2 +Inlb mediated entry of listeria monocytogenes into host cell 0.5245901639344205 0.8555268923983909 0.3922595231915498 1.0 0.6738799925263717 6 O14964,Q99961,P62993,Q92783,P42566 5 +Respiratory electron transport 0.5097918165538053 0.8505887323437049 0.3949978507620648 1.0 0.6765755945637365 44 O75880,P13073,P00403,P47985,O14949,O43676,O75306,O43819,O96000,P03886,Q9UDW1,Q9Y6M9 12 +Transcriptional activation of mitochondrial biogenesis 0.5302250195824485 0.8487106742436091 0.3960423051318265 1.0 0.6766750219686998 11 P48735,Q86X55 2 +Diseases of signal transduction by growth factor receptors and second messengers 0.3092398594049712 0.8324819779667952 0.40513694656176 1.0 0.6873519736161892 127 P60900,P61289,P62942,P49589,O95684,P30154,P28074,Q6RW13,Q9NRY5,P28072,P30086,Q13555,Q06124,P51114,Q99436,P49721,Q02750,Q9GZP9,P31751 19 +Atf4 activates genes in response to endoplasmic reticulum stress 0.5249655412320864 0.8181206972017027 0.4132882716987689 1.0 0.6975534006928591 12 Q96B26,Q9NQT4,Q92945 3 +Recycling pathway of l1 0.5301733470512091 0.8180193335120066 0.4133461477866578 1.0 0.6975534006928591 20 P68371,Q9BUF5,Q9BVA1,Q15418 4 +Initiation of nuclear envelope ne reformation 0.5282544067758106 0.8117685197150876 0.4169244688274451 1.0 0.7010053569010475 18 O95067,P50402,P42167,Q86XL3 4 +Nuclear events kinase and transcription factor activation 0.5229116453553656 0.80826381178734 0.4189387302002187 1.0 0.7035299116703796 12 P51812,Q15418 2 +Ksrp khsrp binds and destabilizes mrna 0.5231810786035187 0.8045473854821859 0.4210809144527165 1.0 0.7062628540698376 13 Q96B26,Q9NQT4,Q92945 3 +Raf activation 0.5119696871323186 0.7815101624385099 0.4345025020282755 1.0 0.7199727449067561 8 Q13555,P30154 2 +Costimulation by the cd28 family 0.515745288966573 0.7796234250517877 0.4356125635254249 1.0 0.7200728158516662 11 P31751,Q06124 2 +Regulation of mecp2 expression and activity 0.5114610025965409 0.7721027428799839 0.4400535778194581 1.0 0.7247941281732252 9 Q13555,P42858 2 +Synthesis of very long chain fatty acyl coas 0.5062607114536906 0.7624706630801407 0.4457791459919209 1.0 0.7298436614569398 7 Q9NZ01 1 +Signaling by egfr 0.5098968519347498 0.7461487509230125 0.4555775626301122 1.0 0.7405834311949216 12 Q14155,O14964,Q06124 3 +Vitamin b5 pantothenate metabolism 0.4963980539172427 0.7450274214505359 0.4562551429616639 1.0 0.7408071670336128 4 P49327,Q9NVE7 2 +Cell surface interactions at the vascular wall 0.5089381379032519 0.7313189179401394 0.4645843778689773 1.0 0.750723864045 14 P35613,Q01650,Q06124,P53985 4 +Cargo concentration in the er 0.5077293306743742 0.730477103108088 0.4650986038179665 1.0 0.750723864045 13 P49755,Q9HCU5,Q15363,P53992,Q96PC5,Q13190,Q12907 7 +Runx1 regulates expression of components of tight junctions 0.4825622775800709 0.7039626427882043 0.4814560383690551 1.0 0.7683623800076462 2 Q13951 1 +G alpha i signalling events 0.5021295243022965 0.677756125349864 0.4979263338101525 1.0 0.7834345527379922 20 O43865,P04083,P30154,Q9NZJ7 4 +Pi3k akt signaling in cancer 0.486697253797937 0.6727587843798356 0.5011007626749753 1.0 0.7852797117871003 7 Q06124 1 +Traf6 mediated irf7 activation 0.4754448398576438 0.6723066391306487 0.5013885040273163 1.0 0.7852797117871003 2 Q14258 1 +Traf3 dependent irf activation pathway 0.4754448398576438 0.6723066391306487 0.5013885040273163 1.0 0.7852797117871003 2 Q14258 1 +Irf3 mediated activation of type 1 ifn 0.4754448398576383 0.6723066391306235 0.5013885040273323 1.0 0.7852797117871003 2 Q9NZI8 1 +Met activates ras signaling 0.4793447293447306 0.6681593292372718 0.5040318936237842 1.0 0.7876215923141594 4 Q9NWH9,Q96P70,P62993 3 +Perk regulates gene expression 0.4929453022715109 0.6552700629436532 0.5122938919086133 1.0 0.7969016096356206 14 Q96B26,Q9NQT4,Q92945 3 +Regulation of innate immune responses to cytosolic dna 0.4757834757834823 0.6522943493967126 0.5142113045746948 1.0 0.798107619775059 4 Q9NZI8,P19474,Q9UJV9 3 +G protein mediated events 0.4854539256676577 0.6516805833687084 0.514607250877789 1.0 0.798107619775059 9 O43865 1 +Signaling by moderate kinase activity braf mutants 0.4869366276408465 0.6513597022180729 0.5148143174205009 1.0 0.798107619775059 10 Q13555,P30086 2 +Response of eif2ak1 hri to heme deficiency 0.4702741189035174 0.6385234258214825 0.5231330098539888 1.0 0.8081006163183786 3 P08243,P20042 2 +Circadian clock 0.4789988679051646 0.6299647151874128 0.5287176701395129 1.0 0.8141421362866572 8 P43490,Q86X55 2 +Signaling by notch2 0.4640569395017775 0.6222392206541606 0.533784579997179 1.0 0.8201035204435941 2 Q92542 1 +Ire1alpha activates chaperones 0.4904659595878838 0.6165322392205067 0.5375433008769634 1.0 0.8233420055949724 22 Q9HCU5,O95070,Q9Y5M8,Q13217,O76024,P43307,P35611 7 +Muscle contraction 0.4901586314352786 0.6129531330001438 0.5399073293416643 1.0 0.8258114335080975 24 Q13555,P04083,P16615,P05023,P60660,P14649,O43865,P08670,P20020 9 +Signaling by braf and raf1 fusions 0.4878897515735209 0.6056802370384233 0.5447271099335711 1.0 0.8322556735287968 21 Q13555,Q02750,Q6RW13,Q9NRY5,P51114,Q53H12,P30086 7 +Unfolded protein response upr 0.4789612445508939 0.5993542836631418 0.5489366559835775 1.0 0.837754273647907 38 Q9HCU5,O95070,Q9Y5M8,Q9NQT4,Q13217,Q9UBS4,Q96B26,O76024,P43307,P35611,Q5RKV6,Q92945 12 +Post translational protein modification 0.2806212083325643 0.5954743207343233 0.5515264592628961 1.0 0.8389072085462234 353 O43852,Q9BU89,O60725,P60900,P61289,P21796,Q8NB78,Q92696,O76024,P46977,P45880,Q9BUN8,Q07065,P53992,Q8TEY7,Q10472,P61978,P28074,Q9BT78,Q9ULX3,Q96K76,P68371,Q8NFH4,P40818,P28072,O43292,Q15388,Q9BVA1,P04843,Q13190,Q9BUF5,Q12907,Q8N1F7,O75935,Q9NXR7,Q99436,Q96RU2,P49721,Q9BTX1,Q15363,Q9BT22,Q13217,O15027,Q9GZP9,P55735,Q15369,Q15293,Q9Y3B3,Q96FW1,Q9Y277 50 +Cellular response to chemical stress 0.3761410721739701 0.5915149122240708 0.5541754665001333 1.0 0.8399354476508766 71 O75880,P13073,P00403,P49721,Q8TED1,P60900,P28074,O43819,P09601,Q86X55,Q8TCT9,P28072,Q99436,P30519 14 +Pkmts methylate histone lysines 0.4737174384090126 0.5911845236349444 0.5543967912112957 1.0 0.8399354476508766 10 Q9H7B4 1 +Copi independent golgi to er retrograde traffic 0.4858158815005078 0.590804752339438 0.5546512504166867 1.0 0.8399354476508766 25 Q9BVA1,Q10472,Q9BUF5,Q15042,P68371,O75935 6 +G beta gamma signalling through cdc42 0.4565836298932431 0.5898207014631011 0.5553108623370335 1.0 0.8400071699298898 2 P63218 1 +Nrage signals death through jnk 0.4631051396968588 0.5860313649685883 0.557854437617292 1.0 0.8403775913171848 5 Q14155,Q9NY61 2 +Interleukin 17 signaling 0.4780673069864235 0.5858082156294598 0.5580044021586454 1.0 0.8403775913171848 14 P51812,Q15418,P30154 3 +Extra nuclear estrogen signaling 0.4725236937450786 0.5858061052959996 0.5580058204737284 1.0 0.8403775913171848 10 P04792 1 +Basigin interactions 0.4652119720646643 0.576611875939141 0.5642016748101697 1.0 0.8469198006997296 7 P53985,Q01650 2 +Negative regulation of mapk pathway 0.4660934033218306 0.5722929393152242 0.5671235323633896 1.0 0.850375394975487 8 P30086,P30154 2 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4658859669725418 0.5635418151616735 0.5730659946789891 1.0 0.8583477562222414 9 Q96DE5,Q9UJX6,Q9UJX4 3 +Cytoprotection by hmox1 0.4185171646493371 0.559766287947263 0.5756388611516225 1.0 0.8598360957078377 60 O75880,P13073,P00403,P49721,P60900,P28074,O43819,P09601,Q86X55,Q8TCT9,P28072,Q99436,P30519 13 +Hcmv early events 0.4691210948915628 0.5593252359916973 0.5759397754777718 1.0 0.8598360957078377 40 Q9BTX1,Q9BVA1,Q9BUF5,P68371,Q8NFH4 5 +Dex h box helicases activate type i ifn and inflammatory cytokines production 0.4459074733095959 0.544192268432831 0.5863091716891926 1.0 0.8677628733091394 2 Q08211 1 +Signaling by retinoic acid 0.4564575838723531 0.5383306337060524 0.5903488060545183 1.0 0.8709231848460206 7 Q15120 1 +Signaling by fgfr2 0.4729393263498012 0.5333952253930674 0.5937600219382551 1.0 0.8730234571094724 21 Q06124,P52597 2 +Signaling by fgfr 0.4729393263498012 0.5333952253930674 0.5937600219382551 1.0 0.8730234571094724 21 Q06124,P52597 2 +Myd88 independent tlr4 cascade 0.470311858482805 0.5309072172622994 0.5954830761905388 1.0 0.8730234571094724 18 P51812,Q06124,Q15418,P30154 4 +Map2k and mapk activation 0.4565196715623228 0.5302755685525311 0.5959208832995253 1.0 0.8730234571094724 8 P30086 1 +Ngf stimulated transcription 0.4421502313990786 0.5173037549817185 0.6049441332268457 1.0 0.8810863596467434 3 P50570,Q00535 2 +Signaling by vegf 0.4697788220986684 0.5158556469463691 0.6059552335743459 1.0 0.8816230969925796 22 Q9UQB8,P04792,O43865,Q7L576 4 +Fgfr2 alternative splicing 0.4645817745872958 0.5134394618784354 0.6076439475768545 1.0 0.8822089905560256 16 P31483,P31943,P52597 3 +Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.4690137069738553 0.5080564305173894 0.6114137692099746 1.0 0.884940024214814 29 P68371,Q9BUF5,Q9BVA1 3 +Hur elavl1 binds and stabilizes mrna 0.4449706571418798 0.5079904840611515 0.6114600167315187 1.0 0.884940024214814 5 Q01105,P39687 2 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.4633759376771944 0.5031469053613202 0.6148609909160991 1.0 0.8867498526084212 17 O43852,Q5JRA6,Q13217,Q02818,O76024,O43493,Q15293,Q07065 8 +Adp signalling through p2y purinoceptor 12 0.4382342470630144 0.5009113176672546 0.6164335370090526 1.0 0.8867498526084212 3 P04899,P63218 2 +Gaba receptor activation 0.4382342470630144 0.5009113176672546 0.6164335370090526 1.0 0.8867498526084212 3 P04899,P63218 2 +Gaba b receptor activation 0.4382342470630144 0.5009113176672546 0.6164335370090526 1.0 0.8867498526084212 3 P04899,P63218 2 +Josephin domain dubs 0.4334519572953751 0.4921097260498759 0.6226417769774726 1.0 0.891342644926049 2 P54727 1 +G alpha z signalling events 0.4383903133903202 0.4908270309400129 0.6235487899110537 1.0 0.891342644926049 4 P04899,P05771,P63218 3 +G alpha s signalling events 0.4383903133903168 0.4908270309399981 0.6235487899110641 1.0 0.891342644926049 4 P04899,P63218,Q9Y3E5 3 +Activation of ppargc1a pgc 1alpha by phosphorylation 0.4330960854092542 0.4906415624029644 0.623679984787906 1.0 0.891342644926049 2 Q16539 1 +Collagen biosynthesis and modifying enzymes 0.4488460443930566 0.4890752258497614 0.6247884400980348 1.0 0.8919976480900144 9 Q32P28,P13674 2 +Trna modification in the nucleus and cytosol 0.4491026251127185 0.4824810631509533 0.6294642476134076 1.0 0.8962116873834525 10 O75648,Q08J23 2 +Signal amplification 0.4387027797576559 0.4714747728110918 0.6373017306343522 1.0 0.9042171400520488 6 P04899,Q14344,Q13685,Q16539,P63218 5 +Negative regulation of the pi3k akt network 0.4444964232364753 0.4627144259402393 0.6435690765511388 1.0 0.9121660878390108 10 P31751,Q06124 2 +Egfr downregulation 0.4382917419456331 0.4524062022584562 0.6509763796492072 1.0 0.9182303918623002 8 Q14155 1 +Disorders of transmembrane transporters 0.3462314417820992 0.4521040830288824 0.6511940023921414 1.0 0.9182303918623002 74 P49721,Q9BTX1,Q9BUN8,Q8N1F7,P60900,P28074,Q9GZP9,P55735,Q8NFH4,P28072,Q99436,P53985 12 +Cell cycle mitotic 0.2780997545314678 0.4509294958359168 0.652040364198889 1.0 0.9184798559351908 233 P50402,P60900,Q7L7X3,Q9Y619,Q86XL3,O95067,Q96DE5,O95684,P30154,P28074,O94927,P68371,Q8NFH4,P42167,P28072,Q14566,P07437,Q9BVA1,P42166,Q9BUF5,Q9Y6X3,Q15005,Q8N1F7,O75935,Q99436,P49721,Q9BTX1,P55735,P31751 29 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.4431081518514572 0.4423036460548742 0.658269492903417 1.0 0.9224658007744098 12 Q9UJX4,Q9UJX6,Q96DE5,O43684,Q9UJX3 5 +Apc cdc20 mediated degradation of nek2a 0.4431081518514572 0.4423036460548742 0.658269492903417 1.0 0.9224658007744098 12 Q9UJX4,Q9UJX6,Q96DE5,O43684,Q9UJX3 5 +Diseases of mitotic cell cycle 0.442903351025716 0.4414266624915896 0.6589041434102927 1.0 0.9224658007744098 12 Q96DE5,P11802,Q9UJX6,Q9UJX4 4 +Toll like receptor tlr1 tlr2 cascade 0.4465293292052809 0.4381119485551307 0.6613051332445896 1.0 0.9231732455451448 15 P51812,Q15418,P30154 3 +Transcriptional regulation of white adipocyte differentiation 0.4305952597733146 0.437942368332791 0.6614280614948085 1.0 0.9231732455451448 6 Q86X55 1 +Class i peroxisomal membrane protein import 0.4363757210558338 0.4362190346458184 0.6626778188073552 1.0 0.9238818807953508 9 P51648,P40855 2 +Translation of sars cov 1 structural proteins 0.4286706467162501 0.4300801762089002 0.6671373198411135 1.0 0.9273681892826826 6 Q10472 1 +Protein folding 0.4506496393368833 0.4221381463573573 0.6729241859113935 1.0 0.92976030520688 33 Q9BVA1,Q9BUF5,P36404,P48643,P68371,P61758,Q9Y2T2,Q15813 8 +Disinhibition of snare formation 0.4175863296546875 0.4168753860093925 0.6767695581258271 1.0 0.9325933004286316 3 P05771,O00186 2 +Heme biosynthesis 0.4222777341839973 0.4144224769601818 0.6785647306122977 1.0 0.9325933004286316 5 Q7KZN9 1 +Pyruvate metabolism and citric acid tca cycle 0.4500650143247872 0.4137704583944986 0.6790422208556315 1.0 0.9325933004286316 29 Q13423,P48735,Q15120,P21796 4 +Nuclear signaling by erbb4 0.416162335350661 0.4112424074283952 0.6808947953393247 1.0 0.9325933004286316 3 P16949,Q92542 2 +Toll like receptor cascades 0.4484801217360945 0.4109532961813268 0.6811067811781777 1.0 0.9325933004286316 24 Q06124,P30154,Q15418,P51812,O60443 5 +Rhov gtpase cycle 0.4362775614113661 0.406469228871803 0.6843978619654527 1.0 0.9331686370187624 13 Q14155 1 +Asparagine n linked glycosylation 0.2811073889018282 0.4026415767275154 0.6872119189191788 1.0 0.9353717785288822 104 P46977,Q9BUN8,Q9Y673,Q9Y678,P53992,Q96PC5,Q5JRA6,Q13561,P68371,P49755,Q9BVA1,P04843,Q13190,Q9BUF5,Q12907,O75935,P27824,Q9HCU5,Q15363,Q9BVK6,Q9BT22,O15027,Q9GZP9,P55735,Q9Y3B3 25 +Rnd1 gtpase cycle 0.4291498733062306 0.3908193784972641 0.6959307499660901 1.0 0.9441863254825388 11 P38159,P51648 2 +G2 m checkpoints 0.3340854949412996 0.3845483141425121 0.7005720939058033 1.0 0.9469802096933616 75 P49721,P60900,P61289,P28074,Q9UQ84,Q9Y619,O95067,P28072,Q9NXR7,Q14566,Q99436 11 +L1cam interactions 0.4418822907744957 0.3762496605098044 0.7067312993755024 1.0 0.9534270823433524 32 P68371,Q9BUF5,Q9BVA1,Q15418 4 +Apoptosis 0.2910082362104721 0.3705565862726349 0.7109678225586076 1.0 0.9572599141809712 83 P49721,Q9NR28,P28072,P28074,P60900,P61289,Q99436,P35611,P08670,P31751,O60313,O60443 12 +G1 s specific transcription 0.4157410417589158 0.3524111044211406 0.7245299753682661 1.0 0.9653705301466928 9 P00374,Q9Y619 2 +Intra golgi and retrograde golgi to er traffic 0.3107822759523575 0.3519573629709322 0.7248702385273365 1.0 0.9653705301466928 79 Q9Y678,Q15363,Q9BVA1,P49755,Q10472,Q13190,Q9BUF5,Q15042,Q8TD16,O75935,P68371,O00461,Q9P2W9,Q9Y3B3,O15260 15 +Oncogenic mapk signaling 0.4335997031696794 0.3431453154264272 0.7314891416205951 1.0 0.9684107115901178 24 Q13555,Q02750,Q6RW13,Q9NRY5,P51114,Q53H12,P30086 7 +Regulation of runx3 expression and activity 0.4335648958289596 0.3410662995465023 0.7330536708137341 1.0 0.9684107115901178 35 P49721,P60900,P28074,P28072,Q99436 5 +Signaling by notch3 0.4083485669735576 0.3406508804988333 0.7333664208033035 1.0 0.9684107115901178 7 P67809 1 +Biological oxidations 0.4252429463659157 0.3295897001387632 0.7417100062296562 1.0 0.9719270784546644 42 Q16850,P07099,O43169,Q9NUJ1,Q8TB61 5 +Signaling by notch 0.4054685825749903 0.329238677285685 0.7419752908049269 1.0 0.9719270784546644 53 P49721,Q15363,P16615,P60900,P61289,P28074,Q96J02,P28072,Q99436,P67809 10 +Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.4114864635416825 0.3277368715134693 0.7431106223139969 1.0 0.9719270784546644 10 Q96DE5,Q9UJX6,Q9UJX4 3 +Potential therapeutics for sars 0.4294095642701953 0.3263172015322352 0.7441843749701944 1.0 0.9719270784546644 37 Q99720,P07437,P21964,P15260 4 +Opioid signalling 0.421202888608311 0.3249977026546937 0.7451828104161304 1.0 0.9719270784546644 16 O43865,P30154 2 +Abc transporter disorders 0.4247501083423451 0.3153206164792027 0.7525182331525835 1.0 0.9766016490202032 40 P49721,Q9BUN8,P60900,P28074,Q9GZP9,P28072,Q99436 7 +Defective cftr causes cystic fibrosis 0.4247501083423451 0.3153206164792027 0.7525182331525835 1.0 0.9766016490202032 40 P49721,Q9BUN8,P60900,P28074,Q9GZP9,P28072,Q99436 7 +Cell death signalling via nrage nrif and nade 0.4030033358285267 0.3116756126101664 0.7552870636866638 1.0 0.9785211061171886 8 Q14155,Q9NY61,Q14344 3 +Abc family proteins mediated transport 0.4125792178076026 0.3095488839826668 0.7569040327303709 1.0 0.979690880100065 48 P49721,Q9BUN8,P60900,P28074,Q9GZP9,P40855,P28072,Q99436 8 +Cell cycle checkpoints 0.2738748213157705 0.3059016984524513 0.7596794927344748 1.0 0.9820920486063888 129 P49721,Q9UJX4,P30154,P28074,P60900,P61289,Q9UQ84,Q7L7X3,P55735,Q9NXR7,Q15005,Q8NFH4,Q9Y619,O95067,P28072,Q96DE5,Q14566,Q99436 18 +Rhou gtpase cycle 0.4107939911100848 0.2959361894155399 0.7672788130682022 1.0 0.9832629875601504 14 Q14155,O43396 2 +Citric acid cycle tca cycle 0.4164066557958106 0.2942765129836162 0.7685466184072902 1.0 0.983624963110823 18 Q13423 1 +Negative regulation of notch4 signaling 0.4216246719287412 0.2906705694794202 0.7713032823252286 1.0 0.9862330879312337 38 P49721,P60900,P61289,P28074,P28072,Q99436 6 +Cyclin a cdk2 associated events at s phase entry 0.4187519005160734 0.2843624883489214 0.7761326028504665 1.0 0.9891056138902916 40 P49721,P60900,P61289,P28074,P28072,P31751,Q99436 7 +E2f mediated regulation of dna replication 0.4018220023202506 0.2830292554233478 0.7771544109138004 1.0 0.9891056138902916 11 Q9Y619 1 +Hcmv infection 0.40573527215098 0.2806850330757285 0.7789519893341299 1.0 0.9904746333331104 49 Q9BTX1,Q9BVA1,P61978,Q9BUF5,P55735,P68371,Q8NFH4 7 +Resolution of sister chromatid cohesion 0.3811713760945653 0.2739924756264291 0.7840904040600494 1.0 0.9931596588576322 59 Q9BVA1,Q9BUF5,Q7L7X3,P55735,P68371,Q15005,Q8NFH4,O95067 8 +Antigen processing cross presentation 0.4078541045853984 0.2732214455270575 0.7846829957738144 1.0 0.9931596588576322 47 P49721,P60900,P28074,Q9UIQ6,P28072,P01889,Q99436,P10321 8 +Postmitotic nuclear pore complex npc reformation 0.4161761821936345 0.270970100505118 0.786414028569481 1.0 0.9944332232233436 23 Q9BTX1,Q9BW27,P55735,Q8NFH4,Q92973,Q12769,Q8N1F7 7 +Regulation of hmox1 expression and activity 0.4121458324210736 0.2663456757555241 0.7899729989175186 1.0 0.9961791861349591 43 P49721,P60900,P28074,P09601,P28072 5 +Collagen formation 0.3962607013354129 0.2623725874200646 0.7930342046571013 1.0 0.9982045218252688 11 Q32P28,P13674 2 +Hdl clearance 0.3711743772241987 0.2570273023190665 0.7971576967069272 1.0 1.0 2 Q8WTV0 1 +Cdt1 association with the cdc6 orc origin complex 0.4136269262214114 0.2544614117020306 0.7991391121120115 1.0 1.0 39 P49721,P60900,Q9Y619,P28074 4 +Foxo mediated transcription 0.3932944247014073 0.2515495848290147 0.8013892311064426 1.0 1.0 11 P31751 1 +Apc c cdc20 mediated degradation of cyclin b 0.3930229948307031 0.2505661430431445 0.8021495607109266 1.0 1.0 11 Q96DE5,Q9UJX6,Q9UJX4 3 +Host interactions of hiv factors 0.2660543827200732 0.2486143765710537 0.8036590867124285 1.0 1.0 92 P49721,Q9BTX1,P12235,Q8N1F7,P28074,P60900,P55735,Q15369,Q8NFH4,P28072,Q99436 11 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.4098702612680345 0.2396521144560692 0.8105999602919121 1.0 1.0 40 P49721,Q03164,P60900,P28074,Q96J02,P28072,Q99436 7 +Rho gtpase cycle 0.2675293089637462 0.2295048276523545 0.8184765688356006 1.0 1.0 138 P50402,P51648,Q13505,P42166,Q9UQB8,Q9BT78,Q7L576,P42167,Q96HY6,O15173,Q96CS3,Q86XL3,P08670,Q07065,Q14155,P30519 16 +Cellular response to hypoxia 0.408666397647599 0.2271942287477388 0.8202727151618694 1.0 1.0 38 P49721,P60900,P28074,Q15369,P28072,Q99436 6 +Depolymerisation of the nuclear lamina 0.3841225947021618 0.2267857007075586 0.8205903832127672 1.0 1.0 10 P50402,P42167 2 +Cyclin d associated events in g1 0.3783939116228583 0.2235111846947794 0.8231376791720548 1.0 1.0 8 P30154 1 +Signaling by the b cell receptor bcr 0.4039986730435656 0.2191255357657878 0.8265522594503962 1.0 1.0 42 P49721,P60900,P61289,P28074,O43865,P28072,Q99436 7 +Regulation of mrna stability by proteins that bind au rich elements 0.3644540611129818 0.2015251923810767 0.8402879328202253 1.0 1.0 61 P49721,Q01105,P61289,P60900,P28074,Q9NQT4,Q14103,Q96B26,P28072,P04792,O00231,Q99436,Q92945 13 +Calnexin calreticulin cycle 0.36785929915691 0.1972522622607323 0.843630134539898 1.0 1.0 7 Q9GZP9 1 +Intrinsic pathway for apoptosis 0.3911655978043595 0.1969035921105285 0.8439029826138822 1.0 1.0 18 Q9NR28,O60443 2 +Hedgehog ligand biogenesis 0.4009910205958408 0.1910625905908146 0.8484765560582663 1.0 1.0 38 P49721,P60900,P28074,Q9GZP9,P28072,Q99436 6 +Mitotic g1 phase and g1 s transition 0.3327861533222878 0.1906946304504917 0.8487648457757286 1.0 1.0 70 P49721,P30154,P60900,P28074,Q9Y619,P28072,P31751,Q14566,Q99436 9 +Transcriptional regulation by runx3 0.3996841849517549 0.190197966124594 0.8491540048294404 1.0 1.0 40 P49721,P60900,P28074,P28072,Q99436 5 +Sphingolipid metabolism 0.3945456757337117 0.1888811043796902 0.8501860035217748 1.0 1.0 22 Q96G23,O95470,O15269,P51648 4 +Signaling by notch4 0.3983100479151031 0.187030941689328 0.851636373023039 1.0 1.0 41 P49721,P60900,P61289,P28074,P28072,Q99436 6 +Cell cycle 0.2586937881200163 0.184959559473415 0.8532607550944897 1.0 1.0 272 P50402,P60900,Q01105,P61289,Q7L7X3,Q9Y619,Q86XL3,O95067,Q96DE5,O95684,P30154,P28074,O94927,P68371,Q8NFH4,P42167,P28072,Q14566,P07437,Q9BVA1,P42166,Q9BUF5,Q9Y6X3,Q15005,Q8N1F7,O75935,Q9NXR7,Q99436,P49721,Q9BTX1,Q9UJX4,Q9UQ84,P55735,P31751 34 +Uch proteinases 0.3960344050822595 0.1843187430649314 0.8537634109863665 1.0 1.0 43 P49721,P60900,Q8NB78,P28074 4 +Transcriptional regulation by ventx 0.3760408342293154 0.1766256308213083 0.8598024601195631 1.0 1.0 13 Q96DE5,Q9UJX6,Q9UJX4 3 +Auf1 hnrnp d0 binds and destabilizes mrna 0.3968082549668721 0.1766154874791365 0.8598104280818164 1.0 1.0 40 P49721,P60900,P28072,P28074 4 +Intra golgi traffic 0.3664730821333773 0.1761157046281881 0.8602030432559731 1.0 1.0 9 O00461 1 +Integrin cell surface interactions 0.3514957264957244 0.1745016697400081 0.8614712186373392 1.0 1.0 4 P05556,P35613,Q08722 3 +Intracellular signaling by second messengers 0.3147114000719569 0.1740154026136839 0.8618533573766691 1.0 1.0 74 Q13555,P49721,Q06124,P30154,P60900,P28074,O43865,P28072,P31751,Q99436 10 +Constitutive signaling by overexpressed erbb2 0.3470986116055561 0.1712631133576767 0.8640168831784214 1.0 1.0 3 Q16543,P62993 2 +Regulation of pten stability and activity 0.3960734419564619 0.1705813247905954 0.8645529833425045 1.0 1.0 39 P49721,P60900,P28074,P28072,P31751,Q99436 6 +Copi dependent golgi to er retrograde traffic 0.3948502473783431 0.1705379004982097 0.8645871306033552 1.0 1.0 41 Q9Y678,P49755,Q9BVA1,Q9BVK6,Q15363,Q9BUF5,P68371,Q9P2W9,Q9Y3B3,O15260 10 +Phosphorylation of the apc c 0.371889400782234 0.1702352426301681 0.8648251366003779 1.0 1.0 12 Q96DE5,Q9UJX6,Q9UJX4 3 +Degradation of gli1 by the proteasome 0.3958316764096384 0.1694695947001486 0.8654272863357706 1.0 1.0 39 P49721,P60900,P28074,Q96J02,P28072,Q99436 6 +Cross presentation of soluble exogenous antigens endosomes 0.3968803483103079 0.1689588687682741 0.8658289941596795 1.0 1.0 35 P49721,P60900,P28074,P28072,Q99436 5 +Degradation of axin 0.3968803483103079 0.1689588687682741 0.8658289941596795 1.0 1.0 35 P49721,P60900,P28074,P28072,Q99436 5 +Signaling by erbb2 ecd mutants 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3 +Signaling by egfr in cancer 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3 +Constitutive signaling by ligand responsive egfr cancer variants 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3 +Constitutive signaling by egfrviii 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3 +Signaling by erbb2 in cancer 0.3472222222222241 0.1619592094673499 0.8713379758315334 1.0 1.0 4 P19174,Q16543,P62993 3 +Er to golgi anterograde transport 0.3396747460367042 0.1613131350041081 0.8718467785066175 1.0 1.0 67 Q9Y678,P49755,Q9BVA1,Q9HCU5,P53992,Q96PC5,Q15363,Q13190,O15027,Q9BUF5,P55735,P68371,Q12907,Q9Y3B3,O75935 15 +Metabolism of polyamines 0.3943603090185318 0.1594061884156795 0.8733488636031856 1.0 1.0 37 P49721,P60900,P28074,P28072,Q99436 5 +Scf skp2 mediated degradation of p27 p21 0.3934822017382032 0.1587314861443225 0.8738804303093914 1.0 1.0 39 P49721,P60900,P61289,P28074,P28072,Q99436 6 +Hedgehog on state 0.393347050022399 0.1581174369041872 0.8743642607894855 1.0 1.0 39 P49721,P60900,P28074,Q96J02,P28072,Q99436 6 +Regulation of pyruvate dehydrogenase pdh complex 0.3498460952030462 0.1507590165848722 0.880165816695915 1.0 1.0 6 Q15120 1 +Transcriptional regulation by runx1 0.3472259482666134 0.1463760501422129 0.8836245328751915 1.0 1.0 64 P49721,Q03164,Q06124,P60900,P28074,Q969G3,Q96J02,P28072,Q99436 9 +Regulation of glucokinase by glucokinase regulatory protein 0.3875017254821782 0.1430596112276307 0.8862431023445232 1.0 1.0 27 Q9BTX1,Q9BW27,Q9BVL2,P55735,P57740,Q8NFH4,Q12769,Q99567,Q8N1F7,Q9NRG9 10 +Sumoylation of ubiquitinylation proteins 0.3875017254821782 0.1430596112276307 0.8862431023445232 1.0 1.0 27 Q9BTX1,Q9BW27,Q9BVL2,P55735,P57740,Q8NFH4,Q12769,Q99567,Q8N1F7,Q9NRG9 10 +Sumoylation of sumoylation proteins 0.3875017254821782 0.1430596112276307 0.8862431023445232 1.0 1.0 27 Q9BTX1,Q9BW27,Q9BVL2,P55735,P57740,Q8NFH4,Q12769,Q99567,Q8N1F7,Q9NRG9 10 +Hemostasis 0.2606641976629967 0.1352767201394003 0.892393090510049 1.0 1.0 106 O43852,Q07021,Q9NZJ7,P18031,P42785,P33176,P20020,Q9NUQ9,P30154,P68371,P53985,Q9BVA1,P16615,Q06124,Q9BUF5,P35613,Q92896,Q6UXV4,Q92769,Q8NBX0,Q01650 21 +Tnf signaling 0.3317906728373124 0.1288116890551748 0.8975066560616409 1.0 1.0 3 P63244,Q15750 2 +Tnfr1 induced nfkappab signaling pathway 0.3317906728373124 0.1288116890551748 0.8975066560616409 1.0 1.0 3 P63244,Q15750 2 +Nuclear pore complex npc disassembly 0.3862198638891151 0.1280866151337501 0.8980804283708186 1.0 1.0 31 O95067,Q9BTX1,Q8NFH4,P55735 4 +Regulation of lipid metabolism by pparalpha 0.3607875412267213 0.1279682760471837 0.8981740786351906 1.0 1.0 13 Q15067,P23786,Q86X55 3 +Rhobtb1 gtpase cycle 0.3728655854155491 0.1274749498178293 0.8985644985678312 1.0 1.0 19 P62995,P08670,Q9BT78,P38159 4 +Transport to the golgi and subsequent modification 0.3280283930356083 0.1273832493952707 0.8986370732801947 1.0 1.0 69 Q9Y678,P49755,Q9BVA1,Q9HCU5,P53992,Q96PC5,Q15363,Q13190,O15027,Q9BUF5,P55735,P68371,Q12907,Q9Y3B3,O75935 15 +Switching of origins to a post replicative state 0.3603242957977433 0.1264123621251549 0.899405517092636 1.0 1.0 58 P49721,Q9UJX4,P60900,P28074,Q9Y619,P28072,Q96DE5,Q14566,Q99436 9 +Plasma lipoprotein assembly 0.3266903914590836 0.124994240419468 0.9005281100594866 1.0 1.0 2 P07237 1 +Signaling by notch1 0.3445698524967702 0.1191333542153672 0.9051697060642891 1.0 1.0 8 Q96J02 1 +Stabilization of p53 0.3845836725538458 0.1172077834610438 0.906695399125054 1.0 1.0 37 P49721,P60900,P28074,P28072,Q99436 5 +Clec7a dectin 1 signaling 0.3826427512259598 0.1171414794796238 0.9067479401161128 1.0 1.0 42 P49721,P60900,O43865,P28074 4 +Purine ribonucleoside monophosphate biosynthesis 0.3461201475563078 0.1154481287783748 0.908089932707923 1.0 1.0 9 Q06203 1 +Mapk6 mapk4 signaling 0.378749469007518 0.1149513454186571 0.9084836870362364 1.0 1.0 46 P49721,P60900,P28072,P28074 4 +Unwinding of dna 0.3453442739921556 0.1132947687421135 0.9097968644779496 1.0 1.0 9 Q9Y248,Q9BRT9,P49736,P33991,Q9BRX5,Q14566,P33992,P33993 8 +Degradation of dvl 0.3831123497901348 0.1108510638185498 0.9117344517625736 1.0 1.0 36 P49721,P60900,P28074,P28072,Q99436 5 +Phosphorylation of emi1 0.3246707013171999 0.1106091784881448 0.9119262687712292 1.0 1.0 3 P53350,P06493 2 +Regulation of tp53 activity through acetylation 0.3470894761046959 0.1103552369704068 0.9121276519551692 1.0 1.0 10 P31751 1 +Vasopressin regulates renal water homeostasis via aquaporins 0.3269230769230755 0.107128232181121 0.914687250002409 1.0 1.0 4 P63218,P10644,P13861 3 +Glucagon signaling in metabolic regulation 0.3269230769230755 0.107128232181121 0.914687250002409 1.0 1.0 4 P63218,P10644,P13861 3 +Neurexins and neuroligins 0.3426146067222229 0.1058147403449243 0.9157293413471724 1.0 1.0 9 O14936 1 +Insulin processing 0.3334291371011158 0.1057525876911887 0.915778655300568 1.0 1.0 6 P33176,O00471,Q8NEW0 3 +Displacement of dna glycosylase by apex1 0.3226056843050702 0.1055176637708332 0.9159650545682962 1.0 1.0 3 P13051 1 +Orc1 removal from chromatin 0.37292593912089 0.1041404351240801 0.9170579027045088 1.0 1.0 49 P49721,P60900,P28074,Q9Y619,P28072,Q14566,Q99436 7 +G1 s dna damage checkpoints 0.3811516362094734 0.1034304485751393 0.9176213472638124 1.0 1.0 38 P49721,P60900,P28074,P28072,Q99436 5 +Ovarian tumor domain proteases 0.3321454027084731 0.102457313232229 0.9183936935896996 1.0 1.0 6 Q14258,P04637,P06493,P55072,Q96FW1 5 +Toll like receptor 9 tlr9 cascade 0.3610319720160698 0.1018695801894947 0.9188601958119956 1.0 1.0 17 P51812,Q15418,P30154 3 +Asymmetric localization of pcp proteins 0.3805868152612884 0.1005496463293361 0.9199079704387872 1.0 1.0 36 P49721,P60900,P28074,P28072,Q99436 5 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.3270395439971473 0.0984544220324895 0.9215714620097688 1.0 1.0 5 P46940,P63218,P10644,P13861 4 +Aquaporin mediated transport 0.3270395439971454 0.0984544220324848 0.9215714620097726 1.0 1.0 5 P10644,P63218,Q99797,P13861 4 +Smooth muscle contraction 0.3480208556022967 0.0979640978944716 0.9219608019275274 1.0 1.0 12 P04083,P60660,P14649 3 +Golgi to er retrograde transport 0.342637045013551 0.0973971332809399 0.922411021217241 1.0 1.0 63 Q9Y678,P49755,Q9BVA1,Q15363,Q10472,Q9Y3B3,Q15042,Q9BUF5,O75935,P68371,Q9P2W9,Q8TD16,O15260 13 +Translation of sars cov 2 structural proteins 0.3543458126290212 0.0949507179984882 0.9243539713235748 1.0 1.0 15 P46977,P04843,Q10472 3 +Sumoylation of rna binding proteins 0.3774202011208876 0.0907263583736175 0.9277100260461713 1.0 1.0 33 Q9BTX1,P07910,P61978,Q9BW27,P55735,Q8NFH4,Q12769,Q8N1F7,Q9NRG9 9 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3736157213022666 0.0906244488229345 0.9277910045143508 1.0 1.0 46 P49721,Q9UJX4,P60900,P61289,P28074,Q9UJX6,O00231,P28072,Q96DE5,Q99436 10 +Rho gtpases activate formins 0.3592431994134051 0.083965299850445 0.9330840210169944 1.0 1.0 55 Q9BVA1,Q9BUF5,Q7L7X3,P55735,P68371,Q15005,Q8NFH4 7 +Adora2b mediated anti inflammatory cytokines production 0.327272727272725 0.0821798264156519 0.934503715363792 1.0 1.0 7 P04899,P13861,P08754,Q9Y3E5,P10644,P63218 6 +Interferon signaling 0.3450346407559533 0.0792261595630409 0.9368527376637816 1.0 1.0 61 Q13555,Q9BTX1,Q06124,P15260,Q9Y3Z3,P55735,Q8NFH4,P01889,P10321 9 +Glycogen synthesis 0.3207847217102634 0.0747491376107373 0.940414310840162 1.0 1.0 6 P46976 1 +C type lectin receptors clrs 0.3711813854192278 0.0719264385614713 0.9426604496071368 1.0 1.0 44 P49721,P60900,O43865,P28074 4 +Apoptotic cleavage of cellular proteins 0.3437329043597913 0.0652896144883114 0.9479434111400746 1.0 1.0 15 P08670 1 +Downstream signaling events of b cell receptor bcr 0.3713833844868901 0.064749824693684 0.9483731916549551 1.0 1.0 40 P49721,P60900,P61289,P28074,P28072,Q99436 6 +Regulation of ras by gaps 0.3712232535249148 0.0631642559930484 0.949635707504478 1.0 1.0 37 P49721,P60900,P28074,P28072,Q99436 5 +Nuclear envelope breakdown 0.3701630100107522 0.0625705973773136 0.9501084434175336 1.0 1.0 42 P50402,Q9BTX1,P42166,P55735,Q8NFH4,P42167,O95067 7 +Copii mediated vesicle transport 0.3631710706144779 0.0613821490209383 0.9510548685672447 1.0 1.0 26 P49755,Q15363,P53992,Q13190,O15027,P55735,Q12907 7 +Rnd2 gtpase cycle 0.3337313291990979 0.0602263734903914 0.9519753408281976 1.0 1.0 12 P38159,P51648,Q07065 3 +Fc epsilon receptor fceri signaling 0.3659837197865968 0.055777628106168 0.9555189573775 1.0 1.0 46 P49721,P60900,O43865,P28074 4 +Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3254817987152096 0.0548603365022055 0.9562497311513722 1.0 1.0 10 P27348,Q04917,O96017,P61981,P06493,Q9Y3B8,P63104,P62258,P31946 9 +Regulation of hsf1 mediated heat shock response 0.3626412168026282 0.0544007933913396 0.9566158467577393 1.0 1.0 49 Q9BTX1,P55735,Q99543,Q8NFH4,P04792 5 +Programmed cell death 0.2505350229983104 0.0538517419153797 0.9570532852070686 1.0 1.0 95 P49721,Q9NR28,P28072,P28074,P60900,P61289,Q99436,P35611,P08670,P31751,O60313,O60443 12 +Interleukin 1 signaling 0.3672551712585986 0.050443466269735 0.95976899938019 1.0 1.0 42 Q02750,P49721,P60900,P28074,P28072,Q99436 6 +Synthesis of pi 0.2918149466192245 0.0480395023863201 0.9616847605823988 1.0 1.0 2 O96017 1 +Rac2 gtpase cycle 0.3650358778992245 0.0476527596486846 0.961992983637691 1.0 1.0 32 P50402,Q13505,Q7L576,P42167,O15173,Q86XL3 6 +Hsf1 dependent transactivation 0.3305462946246925 0.0453723967534492 0.9638104825210958 1.0 1.0 13 P04792 1 +Cellular response to heat stress 0.3518961350379077 0.0451968085524091 0.9639504380589125 1.0 1.0 55 Q13555,Q9BTX1,P55735,Q99543,Q8NFH4,P48723,P04792 7 +Transport of the slbp dependant mature mrna 0.3623779840911095 0.0441998410276195 0.9647451087727386 1.0 1.0 30 Q9BTX1,Q9UBU9,Q9BW27,P55735,Q8NFH4,Q12769,Q8N1F7,Q9NRG9 8 +Fceri mediated nf kb activation 0.3658594362974542 0.0422628231658465 0.96628918160712 1.0 1.0 38 P49721,P60900,P28074,P28072,Q99436 5 +Tcr signaling 0.363690303415465 0.0347641139077591 0.9722678362770548 1.0 1.0 41 P49721,P60900,P28074,P28072,Q99436 5 +Pre notch expression and processing 0.3069258122356644 0.0294805661217774 0.9764813181929128 1.0 1.0 8 P16615 1 +N glycan trimming in the er and calnexin calreticulin cycle 0.3226252289189215 0.026957729379826 0.978493448835593 1.0 1.0 13 Q9BUN8,Q9GZP9 2 +Rhoa gtpase cycle 0.3591862773007259 0.01835344444287 0.985356892131948 1.0 1.0 37 P42166,P42167,Q96HY6,O15173,Q96CS3,Q14155,P30519 7 +Nef mediated downregulation of mhc class i complex cell surface expression 0.2813390313390284 0.0141686804780055 0.9886954068366004 1.0 1.0 4 O43747,P04439,Q10567 3 +Dectin 1 mediated noncanonical nf kb signaling 0.3582034842516484 0.0133862976170854 0.9893195987814264 1.0 1.0 39 P49721,P60900,P28074,P28072,Q99436 5 +Tnfr2 non canonical nf kb pathway 0.3582034842516484 0.0133862976170854 0.9893195987814264 1.0 1.0 39 P49721,P60900,P28074,P28072,Q99436 5 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7084fdc8435ed72c29a0774e413c683cd3c16515 --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha defensins", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective cftr causes cystic fibrosis", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Defensins", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression in beta cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sodium proton exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 dependent activation of irf3 irf7", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc transporters"], "available_proteins": ["AAAS", "AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARL8A", "ARMCX3", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRD1", "BRD2", "BSG", "BUB1B", "BUB3", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCDC8", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDS2", "CENPF", "CENPI", "CEPT1", "CERS2", "CFL1", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT7", "CNOT9", "COG2", "COG4", "COG7", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CRKL", "CRNKL1", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPYSL2", "DR1", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFTUD2", "EHD1", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM49B", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "FYTTD1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOLIM4", "GOLM1", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IRS4", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JMJD6", "JUP", "KARS", "KAT7", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC41", "LRSAM1", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAD2L1", "MAGED2", "MAGT1", "MANBA", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MED24", "MED4", "MFAP1", "MFN1", "MFN2", "MGAT1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MLEC", "MMADHC", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPI", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MYBBP1A", "MYDGF", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA35", "NAE1", "NAGLU", "NAMPT", "NANS", "NAPA", "NARS", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCKAP1", "NCL", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NIT2", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NT5C2", "NT5C3B", "NUB1", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF5A", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIR", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PMPCA", "PMPCB", "PNO1", "PNP", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PTBP1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QPRT", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDX", "REPS1", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEH1L", "SENP3", "SEPT2", "SEPT7", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SGTA", "SH3GL1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35B2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A6", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRAP", "STT3A", "STUB1", "STX18", "STX4", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SWAP70", "SYMPK", "SYNE2", "TAB1", "TACC3", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCP1", "TECR", "TERF2IP", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TK1", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMU", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSPO", "TSR1", "TSR3", "TST", "TSTA3", "TTC21B", "TTC26", "TTC37", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR1", "UBR4", "UBTF", "UCHL5", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VPS25", "VPS26A", "VPS29", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VRK1", "VRK3", "VTA1", "WAPL", "WARS", "WARS2", "WBP11", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WFS1", "WNK1", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YEATS2", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCRB1", "ZFYVE16", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AAAS", "AAMP", "AATF", "ABHD10", "ACAD11", "ACAT2", "ACLY", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ADD1", "AGK", "AGPAT1", "AGPS", "AGTRAP", "AHCYL1", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "ALG5", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKLE2", "ANO6", "ANP32A", "ANXA1", "AP1B1", "AP1G1", "AP3M1", "APOOL", "ARHGEF7", "ARIH2", "ARL2", "ASNS", "ASPH", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BICD2", "BSG", "BUB3", "C1QBP", "CALU", "CAMK2G", "CANX", "CARM1", "CARS", "CASK", "CBFB", "CCNB2", "CCT5", "CD47", "CDC37", "CDK1", "CDK2", "CDK4", "CDK5", "CENPF", "CEPT1", "CERS2", "CHCHD3", "CHEK2", "CHKA", "CKAP4", "COMT", "COPG1", "COPS4", "COX15", "COX2", "COX4I1", "COX7C", "CPNE1", "CPT2", "CRKL", "CYB5B", "CYFIP1", "CYP51A1", "DCTN2", "DCTN3", "DDRGK1", "DDX41", "DERL1", "DERL2", "DHCR24", "DHFR", "DHX9", "DIABLO", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC3", "DNM2", "DOHH", "ECE1", "EIF2S2", "ELOC", "EMD", "EPHX1", "EPS15", "ERAP1", "ERAP2", "EXO1", "EXOC5", "EXOSC5", "EXOSC6", "EXOSC8", "FAF2", "FAM114A2", "FAM49B", "FASN", "FGFR1OP", "FKBP1A", "FKBP5", "FNTB", "FXR1", "GALNT1", "GDAP1", "GINS2", "GINS3", "GINS4", "GLG1", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GOLGB1", "GOLIM4", "GPAA1", "GPD2", "GPX8", "GRB2", "GSDME", "GUSB", "GYG1", "HACD3", "HAUS5", "HDAC2", "HGS", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPK", "HS2ST1", "HSD17B4", "HSPA13", "HSPB1", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IFT27", "IGF1R", "IGF2BP1", "IPO9", "IQGAP1", "ITCH", "ITGB1", "KDM1B", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF5B", "KMT2A", "LGALS3", "LMAN2", "LNPEP", "LPCAT1", "LPGAT1", "LSS", "MAP2K1", "MAPK14", "MAU2", "MBOAT7", "MCL1", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MPP2", "MSMO1", "MTAP", "MTCH1", "MTMR6", "MTOR", "MTX1", "MYH10", "MYL6", "MYL6B", "NAMPT", "NCSTN", "ND1", "NDC1", "NDUFA13", "NDUFAF1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4L", "NELFB", "NLN", "NNT", "NOB1", "NPC1", "NPEPPS", "NSUN2", "NT5C3B", "NUCB1", "NUF2", "NUP107", "NUP160", "NUP37", "NUP58", "NUP85", "NUP88", "NUP93", "NXF1", "OPA1", "OSBPL6", "OSBPL8", "OTUB1", "P3H1", "P4HA1", "P4HB", "PANK4", "PDCD4", "PDE6D", "PDK3", "PEBP1", "PECR", "PEX19", "PGRMC2", "PI4KA", "PIGK", "PITRM1", "PLA2G15", "PLCG1", "PLD6", "PLK1", "PMPCA", "POR", "PPAT", "PPP2R1B", "PRCP", "PREB", "PRKAR1A", "PRKAR2A", "PRKCB", "PRMT1", "PSAP", "PSMA6", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSME3", "PTGES2", "PTGR2", "PTPN1", "PTPN11", "PTRH2", "RAB3GAP1", "RAB4A", "RABGGTA", "RACK1", "RAD21", "RAD23B", "RBMX", "RCN1", "REXO2", "ROCK1", "RPN1", "RPS6KA1", "RPS6KA3", "RTN3", "RTN4", "SACM1L", "SAMHD1", "SAMM50", "SCARB1", "SCCPDH", "SCO1", "SCO2", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC24C", "SET", "SGPL1", "SGTA", "SH3GL1", "SIGMAR1", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A4", "SLC30A7", "SLC35B2", "SLC7A1", "SLC7A5", "SLTM", "SMARCE1", "SMYD3", "SPC25", "SPCS2", "SPTAN1", "SPTLC1", "SQLE", "SQSTM1", "SRPK1", "SRPRB", "SSR1", "STAM", "STARD3NL", "STMN1", "STT3A", "STX18", "STX5", "STXBP3", "SURF4", "TAB1", "TAOK1", "TBCE", "TECR", "TGOLN2", "THOP1", "TIA1", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TMED10", "TMED2", "TMED7", "TMED9", "TMPO", "TNPO1", "TOMM20", "TOMM22", "TOMM5", "TP53", "TP53BP2", "TPM1", "TPM4", "TRA2B", "TRIM21", "TRIM25", "TRMU", "TSPO", "TTC21B", "TTC37", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TXNL1", "UNC119B", "UNG", "UQCR10", "UQCRFS1", "UQCRQ", "USP28", "USP33", "USP47", "USP8", "VAMP7", "VBP1", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "WFS1", "WNK1", "YBX1", "YIF1A", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ"]} \ No newline at end of file diff --git a/msigdb_wp/advanced/idx2term.json b/msigdb_wp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..362372847ec1c070dcfefbec81b8325c486c62b5 --- /dev/null +++ b/msigdb_wp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Alzheimers disease and mirna effects", "1": "Alzheimers disease", "2": "Overlap between signal transduction pathways contributing to lmna laminopathies", "3": "Allograft rejection"} \ No newline at end of file diff --git a/msigdb_wp/advanced/plot_0.png b/msigdb_wp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0dd95da5859c3e236fc90f6d8fb1b66ae70c0c2d --- /dev/null +++ b/msigdb_wp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5704ebe39aad8fbf806149d23c185af687e36018032f50657b7f229262627d8e +size 205637 diff --git a/msigdb_wp/advanced/plot_1.png b/msigdb_wp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d76cececbded0d949d7c7daea39537b2e8693642 --- /dev/null +++ b/msigdb_wp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:078f40314b458296744a4e283268920341c405f2b3c1ee6fa3171d3e789123bb +size 201478 diff --git a/msigdb_wp/advanced/plot_2.png b/msigdb_wp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..e4dbe6b8a6719bdafd9c08f01f8d0ff7680d3f41 --- /dev/null +++ b/msigdb_wp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:070a9444966f8e7335023bbabb2069da16351b955dc9c64d045247803f3b192f +size 200524 diff --git a/msigdb_wp/advanced/plot_3.png b/msigdb_wp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..0ef05a3c213f433cad04dedc03130f44dce70120 --- /dev/null +++ b/msigdb_wp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1241e7fe93b3be8035771e66d4538224c6723dbfa442155ee0401557b6a36d34 +size 188376 diff --git a/msigdb_wp/basic/idx2term.json b/msigdb_wp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..eb03f8937ad2a5d2237b3f588c6a0abd4d8c437b --- /dev/null +++ b/msigdb_wp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Alzheimers disease and mirna effects", "1": "Alzheimers disease", "2": "Overlap between signal transduction pathways contributing to lmna laminopathies", "3": "Allograft rejection", "4": "Mitochondrial complex iv assembly", "5": "Vitamin d receptor pathway", "6": "Electron transport chain oxphos system in mitochondria", "7": "Nonalcoholic fatty liver disease", "8": "Modulators of tcr signaling and t cell activation", "9": "Oxidative phosphorylation", "10": "Cholesterol metabolism with bloch and kandutschrussell pathways", "11": "Proteasome degradation", "12": "Envelope proteins and their potential roles in edmd physiopathology", "13": "Head and neck squamous cell carcinoma", "14": "Myometrial relaxation and contraction pathways", "15": "Egfegfr signaling pathway", "16": "Ranklrank signaling pathway", "17": "Ethanol effects on histone modifications", "18": "Angiopoietinlike protein 8 regulatory pathway", "19": "Photodynamic therapyinduced unfolded protein response", "20": "Mecp2 and associated rett syndrome", "21": "Hepatitis b infection"} \ No newline at end of file diff --git a/msigdb_wp/basic/plot_0.png b/msigdb_wp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f3b405f0c3f92809c2b3f91cf4d26fff7d1be4fc --- /dev/null +++ b/msigdb_wp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:794e4bf815bb78c7e21a58a038a47c18ed20a9b54a2a4b851be5eea32c02eacb +size 147267 diff --git a/msigdb_wp/basic/plot_1.png b/msigdb_wp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..55010f38b80f746e0561af471639fe1ad5b4830a --- /dev/null +++ b/msigdb_wp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:068b3484b10d822be1de2a3df83c953423526bc3824476a0a916604329ac3a2e +size 137161 diff --git a/msigdb_wp/basic/plot_10.png b/msigdb_wp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..d12de00fbecb523d133e1c737b53ee32ef8809cb --- /dev/null +++ b/msigdb_wp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d96ef2c2c6ee6fbe2340f45b7e8593386ba6e53378b47fe4ec63953b33ef970f +size 144835 diff --git a/msigdb_wp/basic/plot_11.png b/msigdb_wp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..22ac65ec9f00005dafea8b58d500a184b826623a --- /dev/null +++ b/msigdb_wp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ad3c60a77124236f7d541d4ca067398d0eb7df71e3b46b4452dc216a767f9b29 +size 145994 diff --git a/msigdb_wp/basic/plot_12.png b/msigdb_wp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..89a4f0d95fc44309264f992d15b1f38cf551c7a8 --- /dev/null +++ b/msigdb_wp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c62e65cc4f6373b6bc9e935f7f14c736974aef9139335b80051213d4ffa1dc54 +size 142707 diff --git a/msigdb_wp/basic/plot_13.png b/msigdb_wp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..077a074630a21b8ba639ed1b899fa18eef7b03e0 --- /dev/null +++ b/msigdb_wp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c1083920483537fafa21cdf055de63a3e18b6f5b18e62c9877ae0aca1195b2a8 +size 152333 diff --git a/msigdb_wp/basic/plot_14.png b/msigdb_wp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..700a03df354e8b3f2122e850256d2b3cf00a075d --- /dev/null +++ b/msigdb_wp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1994361ce1561f5e3a340a3f9ba2e286efcb31d056b6329fc745bf09db7ba94d +size 152548 diff --git a/msigdb_wp/basic/plot_15.png b/msigdb_wp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..8ae49b78de54f82dbdbb039a6a74b376c8162d27 --- /dev/null +++ b/msigdb_wp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ddbdb41b61237b0d35bb63cb9ff5b4db801d8a9f8f3dfe9fe8020e3b426bfa89 +size 151524 diff --git a/msigdb_wp/basic/plot_16.png b/msigdb_wp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..0644df3da71c4a8e2085a7f907d986b9784bba5b --- /dev/null +++ b/msigdb_wp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b4d8e9e1476d7e3c08b7061d937e92599d4e41d3c95e5eca5cccd16a7dab412 +size 148251 diff --git a/msigdb_wp/basic/plot_17.png b/msigdb_wp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..65a540af35ef6321aabcc41e82959ee452bd1097 --- /dev/null +++ b/msigdb_wp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31dc75ad391e1b0f7864dd3446ae18b7dc54e4f70bc75d552c07b6cb704cbdb4 +size 144905 diff --git a/msigdb_wp/basic/plot_18.png b/msigdb_wp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..f1b4612fe6bcd9bb5d94aec95921e4b79e029327 --- /dev/null +++ b/msigdb_wp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3121cf76357750156b27ad7123d600cc4f8ca3729316eca3f2b84bd8ed27b106 +size 146829 diff --git a/msigdb_wp/basic/plot_19.png b/msigdb_wp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..ba305cb78e1f2189835fefa12b2f541bd86812ba --- /dev/null +++ b/msigdb_wp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15235419f7715291c84607ce1a8bd405fac6fe5f80f06c1beb7dc1f72a1b8266 +size 151959 diff --git a/msigdb_wp/basic/plot_2.png b/msigdb_wp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..99b1ebda35d0a920f299268af0cf472f7e42beb2 --- /dev/null +++ b/msigdb_wp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17b7b7dfcc39477f8ab1ff9e1b8a33048da2706f19d99c2f0b3ee0a7ead3ab0f +size 142385 diff --git a/msigdb_wp/basic/plot_20.png b/msigdb_wp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..7b22dc1b3b5a0ebfaa1864917546c46a130b7d57 --- /dev/null +++ b/msigdb_wp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c597696a165cc66b826d173eea5623eefca75b4965e59d2f94d81e06e907869 +size 142037 diff --git a/msigdb_wp/basic/plot_21.png b/msigdb_wp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..a13068918fba0f0778ba645944f07640e7a732c0 --- /dev/null +++ b/msigdb_wp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2630f18299af328f3e2f542e7e0e60ffd5347f1311442b21fc807bb3e0a5081f +size 137921 diff --git a/msigdb_wp/basic/plot_3.png b/msigdb_wp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..7286673dfce59bcf35e16e3207c2c089bbcea86f --- /dev/null +++ b/msigdb_wp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1daed186df15acdf181e30255f279bd790e091023bada2c1641221cb7cd681c9 +size 131641 diff --git a/msigdb_wp/basic/plot_4.png b/msigdb_wp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7cee3202d1f5bb253659b53d81368ab33261500b --- /dev/null +++ b/msigdb_wp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ec05f92fdf864dc156d47fcb286788b97c87003ffef71f49f99dcc62dd7dda8 +size 136763 diff --git a/msigdb_wp/basic/plot_5.png b/msigdb_wp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..70e282e097f08afe27aed468f53c2023a33fd267 --- /dev/null +++ b/msigdb_wp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:087556cb5a50211164dc4c928299fa81516153f37265ce6a7abec09aaef423a0 +size 135162 diff --git a/msigdb_wp/basic/plot_6.png b/msigdb_wp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..abbccbb51c065229e135c8d197c14e5340c9c115 --- /dev/null +++ b/msigdb_wp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9588cba0b433272ec9b8614bc5df1ea2d5f624638611a52dbc8eea6b0a91e29f +size 143877 diff --git a/msigdb_wp/basic/plot_7.png b/msigdb_wp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..0b64ce1a45abd3093f56d67b8ae256eee29cf780 --- /dev/null +++ b/msigdb_wp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c368ba37998d58dbd743ec642b7ccfa1d7675276b5b941fc2733df0d68daeef1 +size 141664 diff --git a/msigdb_wp/basic/plot_8.png b/msigdb_wp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..ab17b65edd391787a29e7e0451b602c36030d5b3 --- /dev/null +++ b/msigdb_wp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8165fcd18d7933e0e05bfbd2a5d352936cf84601cf0e4fd7e925ad0101293fca +size 141269 diff --git a/msigdb_wp/basic/plot_9.png b/msigdb_wp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..f906e7d999341d665ae497435b3329a64a5a7aa6 --- /dev/null +++ b/msigdb_wp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b488026305363ac31e5ad2e5c878c8679111aa1e5f4193475255091e1571fe4a +size 142578 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ed9bf1cc6ebe47a94f301b0dfae835956ba151db --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c0210bdbefd51115d0c0f40890bbbf9e049fde688616c17e6893ae43a2e828b2 +size 106332 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..25c1eec9427de99e4d44aa35ba8809c05c947f49 --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Alzheimers disease and mirna effects 14 73 2.652274882014581 0.007995142271111 19.78640776699029 84.62864077669903 0.8675405351918691 0.5019659822826982 9.06411947478317 6.212690980603589 1.0744065053186531 0.3869842050583563 1.242059637152688e-05 0.0023336679986501 1.840528961883049e-05 8.86462613009299e-05 0.0016022636688124 +Influence of laminopathies on wnt signaling 2 9 2.471391181903304 0.0134588505288426 2.929611650485437 10.199029126213592 1.172665957836072 0.274405530989148 1.5096443497648335 1.3031697834850824 0.8784257604250459 0.2713478851839423 0.0594814219557023 0.1321770275159086 0.032784445092202 0.1617118829485157 0.1766336232289773 +Alzheimers disease 13 71 2.4496969477246497 0.0142976494458308 18.929611650485437 83.0752427184466 0.8523996335219438 0.5089902911900335 9.09856474570077 6.061710858604258 1.0800674607776464 0.3865214102951685 5.613783179315315e-05 0.0021841382931177 1.6128911479806496e-05 0.0002670057770289 0.0031261199916538 +Acquired partial lipodystrophy barraquersimons syndrome 0 5 2.4395478555028083 0.0147056547623691 1.7402912621359223 4.497572815533981 0.9065154927122356 0.2548673055649036 1.4953091418597944 0.5048251951988992 1.235575791841686 0.2574096858611674 0.0891072447823885 0.0325017468768143 0.0647424502180396 0.1565948204648432 0.2942334307578267 +Cholesterol biosynthesis with skeletal dysplasias 1 5 2.426511091450213 0.0152447843289127 2.703883495145631 6.024271844660194 1.6250539245333766 0.1427602110791373 1.3052115351448448 0.7101163612316155 0.9675759117714408 0.205892393525391 0.0034987262668531 0.0325017468768143 0.0018236078239645 0.0111508905617615 0.0419919493306108 +Overlap between signal transduction pathways contributing to lmna laminopathies 6 14 2.105733304287328 0.0352275251642018 4.927184466019417 14.766990291262136 1.2077866030529698 0.2877996039599693 1.943257907759383 1.4611731122572065 0.935661776029738 0.2919054664837305 0.1193276501658733 0.1916891885455893 0.0681167311872175 0.0931972749461429 0.0055591316089767 +Familial partial lipodystrophy fpld 2 8 2.0408657869946096 0.0412641693136912 2.7354368932038833 7.351941747572815 1.0487704575374006 0.2220749325398317 1.64741826657551 0.7567951823729889 1.2080189526980365 0.2461617416466816 0.0310048988007753 0.0944323477659319 0.016724444992627 0.0895680133917324 0.0790607116166092 +Allograft rejection 5 9 1.9854674689505916 0.0470924859836894 3.3300970873786406 9.83980582524272 0.7953176037476221 0.3759733848734315 1.6481136585050014 1.3214319833302084 0.931941180031962 0.288328422601957 1.0 1.0 1.0 0.0345219152795696 0.0027845492980534 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c1d6546a3d809fa78762618340ac7d5fa59df991 --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 586, + "title": "Average number of proteins per term", + "value": 9.319112627986348 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..54038fc5dfa701ef97e8df61f5b2d09f95b7b43e --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..71a218cd7680d11dff1d64a9f223b6d22f3c8cfa --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,151 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Alzheimers disease and mirna effects 0.5928406775053837 2.652274882014581 0.007995142271111 0.9909408776620212 0.1337723513211494 73 P49721,P07437,Q9BVA1,P28072,Q9NQC3,P28074,P60900,Q9BUF5,P21796,P68371,O95197,Q96GC9,P45880,Q9Y277 14 +Metabolism of spingolipids in er and golgi apparatus 0.8964044143823482 2.5611262221677715 0.0104333442390438 0.9978580908835628 0.1337723513211494 3 O95470,Q06136 2 +Oxidation by cytochrome p450 0.89535281473535 2.553899227698514 0.0106524081597023 0.9981187089712252 0.1337723513211494 4 O43169,Q16850 2 +Copper homeostasis 0.8846092050704368 2.5118186490974828 0.0120110794815904 0.9991591557182192 0.1337723513211494 3 O75880 1 +Urea cycle and related diseases 0.8772241992882628 2.484488507755124 0.0129737695693419 0.9995250861290764 0.1337723513211494 2 Q9Y619 1 +Influence of laminopathies on wnt signaling 0.8761047421120427 2.471391181903304 0.0134588505288426 0.9996439508211404 0.1337723513211494 9 O75844,O60725 2 +Alzheimers disease 0.5864153723334851 2.4496969477246497 0.0142976494458308 0.9997837111026284 0.1337723513211494 71 P49721,P07437,Q9BVA1,P28072,Q9NQC3,P28074,P60900,Q9BUF5,P21796,P68371,O95197,P45880,Q9Y277 13 +Kennedy pathway from sphingolipids 0.8693485226059121 2.447586268961792 0.0143816691693385 0.999794249730098 0.1337723513211494 3 Q9Y6K0,O95470 2 +Cholesterol biosynthesis with skeletal dysplasias 0.86586801330151 2.426511091450213 0.0152447843289127 0.9998768660649472 0.1353552063142858 5 Q15392 1 +Nanomaterial induced apoptosis 0.8579565681737411 2.399313770371226 0.0164258327510982 0.9999390507020048 0.1395005506107761 3 Q9NR28,O95831 2 +Triacylglyceride synthesis 0.8533285866856577 2.3796238104671055 0.0173303200906931 0.999964450956222 0.140153007513346 3 O00116,Q99943 2 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.8533837757841891 2.3761905433009742 0.0174924271984495 0.9999677268635704 0.140153007513346 4 P09601 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.8508896797153094 2.373435215713086 0.0176234843670952 0.999970153632146 0.140153007513346 2 Q07820 1 +Eicosanoid synthesis 0.8263345195729546 2.268553591723348 0.0232954865008181 0.9999989971590192 0.1735550825615177 2 Q9H7Z7 1 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.7917600465792004 2.1057333042873276 0.0352275251642018 0.9999999992535616 0.219609890917258 14 P50402,P42166,O60725,P42167,P55209,O75844 6 +Familial partial lipodystrophy fpld 0.7791462907275665 2.0408657869946096 0.0412641693136912 0.999999999981138 0.2492866311115781 8 O75844,O60725 2 +Apoptosis modulation by hsp70 0.7692778716321136 2.0140606282290032 0.044003168515371 0.9999999999964724 0.2604631994950243 3 O95831 1 +Allograft rejection 0.7671230374115695 1.9854674689505911 0.0470924859836894 0.9999999999994706 0.2690988888346523 9 Q9BY49,P49327,P08670,P01889,P10321 5 +Mirna regulation of p53 pathway in prostate cancer 0.7534873311961342 1.9437210426507068 0.0519290996740449 0.9999999999999732 0.2766404764453665 3 O14681 1 +Irinotecan pathway 0.7338078291815038 1.8619081813628937 0.0626160336506864 1.0 0.3027417861712447 2 O15118 1 +Apoptosis modulation and signaling 0.7399720323857175 1.861881734096135 0.0626197622589614 1.0 0.3027417861712447 8 Q9NR28,O95831,Q07820 3 +Mitochondrial complex iv assembly 0.7403352368383642 1.8609031741096116 0.0627578514655862 1.0 0.3027417861712447 11 P00403,Q7KZN9,Q9Y2R0,O43819,P14406 5 +Hostpathogen interaction of human coronaviruses mapk signaling 0.7240655758191598 1.793741509514284 0.0728544365855365 1.0 0.3350384646934648 6 P51812,Q15418 2 +Mitochondrial complex iii assembly 0.7250006798128404 1.7908031060182974 0.0733248966680681 1.0 0.3350384646934648 9 O14949,Q9UDW1,Q6DKK2 3 +Praderwilli and angelman syndrome 0.7067316969573396 1.7196362406664427 0.0854985842444828 1.0 0.3630592055599055 5 P11802,Q7L576 2 +Vitamin d receptor pathway 0.7067300098644059 1.7023627271884971 0.0886873926572076 1.0 0.3738907345116809 11 Q92604,P04080,Q5VV42,Q96KA5,P20020 5 +Sphingolipid metabolism overview 0.697848423700511 1.6727092955121328 0.094384538420069 1.0 0.384092635515003 6 Q96G23,O95470,O15269 3 +Sphingolipid metabolism integrated pathway 0.697848423700511 1.6727092955121328 0.094384538420069 1.0 0.384092635515003 6 Q96G23,O95470,O15269 3 +Type ii interferon signaling ifng 0.6918989522966053 1.6450722279669086 0.0999549169945905 1.0 0.3984597371348984 6 P01889,P15260 2 +Sphingolipid pathway 0.6885046552462544 1.6221116728867848 0.1047794392520184 1.0 0.4068668308728673 8 Q96G23,O95470,O15269 3 +Tryptophan metabolism 0.6863735066805585 1.60361196160095 0.1087996124532728 1.0 0.4068668308728673 13 Q15392,P51648 2 +Striated muscle contraction pathway 0.6794300727211668 1.593321054225923 0.1110881858374814 1.0 0.4068668308728673 5 O43707,P08670,P09493 3 +Signal transduction through il1r 0.6743772241992966 1.591817158373985 0.1114257936378089 1.0 0.4068668308728673 2 Q15750 1 +Mirnas involvement in the immune response in sepsis 0.6743772241992966 1.591817158373985 0.1114257936378089 1.0 0.4068668308728673 2 Q15750 1 +Monoamine transport 0.6743772241992874 1.5918171583739424 0.1114257936378184 1.0 0.4068668308728673 2 O15127 1 +Pathogenic escherichia coli infection 0.673275564581932 1.5444131906730196 0.1224882665362008 1.0 0.4265484285003482 18 P07437,Q9BVA1,P68371 3 +Progeriaassociated lipodystrophy 0.668830684438867 1.5232556050883483 0.1276947693915184 1.0 0.4351730868988343 10 O60725 1 +Apoptosis 0.6664961563128202 1.512076124938749 0.1305144977789565 1.0 0.4351730868988343 10 Q9NR28,Q07820 2 +Electron transport chain oxphos system in mitochondria 0.6035944794384731 1.50843564655485 0.1314430654967469 1.0 0.4351730868988343 47 O75880,P13073,P12235,O43676,P03886,P36542,P56134,P14406,P00403,O75964,P24539,P06576,P56385,Q7KZN9,P47985,O96000,P21912,Q9UDW1,P15954,Q9Y6M9,P12236,O95168,O14949,O75306 24 +Relationship between inflammation cox2 and egfr 0.6475834932969144 1.45986269474869 0.1443278137392309 1.0 0.4672335808686954 3 P31751 1 +Cellular proteostasis 0.6502465995052078 1.4570104297706048 0.1451135012254309 1.0 0.4672335808686954 5 P61758,O15212,Q99471 3 +Mitochondrial complex i assembly model oxphos system 0.6474860356529206 1.4192030483893128 0.1558398274962655 1.0 0.4883536840257306 20 P03886,Q9Y6M9,O43676,Q96CU9 4 +Photodynamic therapyinduced ap1 survival signaling 0.64214691234516 1.411825196271201 0.1580014376030327 1.0 0.491459898204954 6 Q07820 1 +Nonalcoholic fatty liver disease 0.5940373740404897 1.3408444239275674 0.1799709694662052 1.0 0.516975431898021 42 P00403,P13073,P47985,O14949,O43676,O75306,O96000,P49327,Q9UDW1,Q96J02,Q96GC9,P31751,P14406,Q9Y6M9 14 +Cytosine methylation 0.6247049577736078 1.336846940832464 0.1812726032488147 1.0 0.5181743683112462 5 P48735 1 +Bdnftrkb signaling 0.6251005940131384 1.3258166604892154 0.1849004330944774 1.0 0.5259789019095329 7 Q15418 1 +Nocgmppkg mediated neuroprotection 0.6143701092410838 1.2962130710958326 0.1949020874940368 1.0 0.543869634626217 4 P30536 1 +Small cell lung cancer 0.611264067039408 1.2655913959193308 0.2056594080987359 1.0 0.5620588755527924 6 P31751 1 +Tcell receptor tcr signaling pathway 0.6151692872965646 1.2610672242763117 0.2072846280818583 1.0 0.5620588755527924 11 Q02750,P08670,Q06124 3 +Omega3 omega6 fatty acid synthesis 0.6061999991110346 1.249445907917314 0.211502026259486 1.0 0.5685329696699944 5 O15254 1 +Glycerophospholipid biosynthetic pathway 0.6010197920687735 1.2169489974719505 0.2236236216276987 1.0 0.5810297126956213 6 Q9Y6K0,O00116 2 +Eicosanoid metabolism via lipooxygenases lox 0.5828359289574027 1.1389174362250731 0.2547375923896746 1.0 0.6004439931889981 5 O15254,Q15067,Q8N8N7 3 +Ppar signaling pathway 0.5765989610378763 1.0731280647768566 0.2832136605786244 1.0 0.6234021834864343 11 P23786 1 +Mitochondrial long chain fatty acid betaoxidation 0.5770589960530766 1.0712843172296074 0.2840416091994504 1.0 0.6234021834864343 12 O43772,P23786 2 +Kisspeptinkisspeptin receptor system in the ovary 0.5644836709815161 1.0612629995067748 0.2885703958649983 1.0 0.6259905250762468 4 Q02750,P31751 2 +Neuroinflammation 0.5624668097347866 1.051777875597918 0.2929014719627285 1.0 0.6259905250762468 4 P00403,P42345 2 +Lncrnamediated mechanisms of therapeutic resistance 0.5580071174377145 1.05029777986961 0.2935812256073469 1.0 0.6259905250762468 2 P08183 1 +Lung fibrosis 0.5510387138553837 0.9887769774846432 0.322772270721638 1.0 0.6584904343596482 5 P09601 1 +Eicosanoid metabolism via cyclooxygenases cox 0.5492584650177964 0.9803998554647678 0.3268887810802381 1.0 0.661591269878488 5 O15254,Q8N8N7 2 +Disruption of postsynaptic signaling by cnv 0.5523974965209811 0.9792007304522156 0.3274808077898918 1.0 0.661591269878488 7 Q13555,Q7L576 2 +Modulators of tcr signaling and t cell activation 0.553122169586713 0.9642735902033996 0.3349087779391575 1.0 0.6702859413462985 10 Q9NQG5,Q14344,O95376,Q93034,O96000,Q15366 6 +Histone modifications 0.542206516955008 0.9309000705536478 0.3519052580302313 1.0 0.6955534612862616 7 Q03164,Q9H7B4 2 +Ketogenesis and ketolysis 0.5365218338541452 0.9114283517644424 0.362069720822789 1.0 0.7028952303877835 6 O43772,P23786 2 +Molybdenum cofactor moco biosynthesis 0.5241992882562281 0.8933262925669635 0.3716824617210497 1.0 0.7188314276189277 2 Q969Z3 1 +Extracellular vesiclemediated signaling in recipient cells 0.5240299038803795 0.8821129800589813 0.3777157136060571 1.0 0.7257095349939328 3 P42345,P35222 2 +Tcell antigen receptor tcr pathway during staphylococcus aureus infection 0.5291687962662577 0.8769376688473098 0.3805204946348941 1.0 0.7269833437537471 6 Q02750 1 +Mir124 predicted interactions with cell cycle and differentiation 0.5185053380782821 0.8671017700696309 0.385886250848662 1.0 0.7318101715123494 2 Q13131 1 +Thermogenesis 0.5389796280626921 0.8637319154015842 0.387735176961401 1.0 0.7329445603205839 24 O43772,P51812,P23786,Q15418 4 +Oxidative phosphorylation 0.5371556383241752 0.8558327048857052 0.3920903222833147 1.0 0.7340732551374519 25 O75964,O75306,O96000,P24539,P03886,P56134,Q9Y6M9 7 +Endothelin pathways 0.5178670523497082 0.8164365901350388 0.4142504763747943 1.0 0.7631125812365266 7 Q02750,P00403,P16615 3 +Il1 signaling pathway 0.5189960505817857 0.8144022885657376 0.4154145280110102 1.0 0.7631125812365266 8 Q02750,Q06124 2 +Vitamin dsensitive calcium signaling in depression 0.511206043700521 0.8028526586935678 0.4220599016473509 1.0 0.7698243100054873 5 Q8NB78 1 +Spinal cord injury 0.5210646286138534 0.7787387653802579 0.4361336156396622 1.0 0.7814847423158374 17 Q9NQC3,P04083 2 +Camkk2 pathway 0.5115666119211957 0.7659935556596681 0.4436801366710214 1.0 0.7878683639067229 10 Q14155,P09601 2 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.5178477174957872 0.7577885920491768 0.4485775528511024 1.0 0.789442765792365 19 Q16850,Q15800,P48449,Q9BWD1,P37268,Q15392,Q14534 7 +Bladder cancer 0.4991898655873184 0.7577373056678945 0.4486082611072655 1.0 0.789442765792365 4 Q02750 1 +Netrinunc5b signaling pathway 0.5069978172443633 0.7445210668098216 0.4565613010508915 1.0 0.8000192650107756 10 Q06124,P30154 2 +Mirna regulation of prostate cancer signaling pathways 0.5020938017747867 0.74321933824862 0.4573488972331225 1.0 0.8000192650107756 7 Q8NCF5 1 +Sphingolipid metabolism in senescence 0.5029914328545114 0.7194021379325697 0.4718931799574315 1.0 0.8133217748678084 11 Q96G23,O15269 2 +Complement and coagulation cascades 0.4822064056939526 0.7023737503230356 0.4824461110223146 1.0 0.8208323703483457 2 P49257 1 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.4976870667660387 0.694565339287746 0.4873277400647571 1.0 0.8253585424218141 11 Q96AY3,Q32P28,P13674 3 +Parkinubiquitin proteasomal system pathway 0.5013083531229166 0.6868639571229851 0.4921684616966977 1.0 0.829145597100508 32 P07437,P68371,Q9BUF5,Q9BVA1 4 +Sars coronavirus and innate immunity 0.4754448398576438 0.6723066391306487 0.5013885040273163 1.0 0.8383209812833118 2 P42224 1 +Serine metabolism 0.4818228846122458 0.6689834091818087 0.5035060613245701 1.0 0.8383209812833118 5 O43175 1 +Erbb signaling pathway 0.4913217001874939 0.6587530994927713 0.5100543289567665 1.0 0.8443272225103536 12 Q02750,P31751,P05771,Q13555 4 +Phosphoinositides metabolism 0.4783427838246935 0.643451715797484 0.5199310355638902 1.0 0.8503944861039109 6 Q9Y217 1 +Insulin signaling in adipocytes normal condition 0.4735063704115133 0.6421879135008642 0.5207511797018602 1.0 0.8503944861039109 4 P31751,O60343 2 +Insulin signaling in adipocytes diabetic condition 0.4735063704115133 0.6421879135008642 0.5207511797018602 1.0 0.8503944861039109 4 P31751,O60343 2 +Endometrial cancer 0.4810306307389422 0.639141191154715 0.5227310854808436 1.0 0.8508900446993731 8 Q02750,P31751 2 +Ptf1a related regulatory pathway 0.4640569395017659 0.6222392206541093 0.5337845799972127 1.0 0.8569801750092236 2 P35222 1 +B cell receptor signaling pathway 0.4814446937758046 0.6070370145542076 0.543826348087654 1.0 0.8683439781454093 13 Q06124,Q15418 2 +Fatty acid betaoxidation 0.4842391103597047 0.6004247841718083 0.5482231745082102 1.0 0.8729858159288347 17 O43772,P23786 2 +Metastatic brain tumor 0.4565836298932245 0.5898207014630216 0.5553108623370868 1.0 0.8794923387284673 2 P04637 1 +Ccl18 signaling pathway 0.4708402125573805 0.5856161272848289 0.558133508274139 1.0 0.8809552570997777 9 Q96GC9,P08670,Q86UE4 3 +Oxidative damage response 0.4567461730153006 0.5795058589204853 0.562247894462998 1.0 0.8809552570997777 3 P45985,P12004 2 +Proteasome degradation 0.4670012741899924 0.5471900252672963 0.5842481882682793 1.0 0.8972929411260614 40 P49721,P04843,P60900,P61289,P28074,P28072,P01889,Q99436,P10321 9 +Onecarbon metabolism and related pathways 0.4647605774232355 0.5439789379237054 0.5864559666404121 1.0 0.8972929411260614 11 Q9Y6K0,O43865 2 +Cholesterol biosynthesis pathway 0.4624729199927768 0.5337930444649446 0.5934847265663596 1.0 0.9056824212705384 11 Q14534,Q16850,P48449,Q15800 4 +Cerebral organic acidurias including diseases 0.4436124513452364 0.5127265085696324 0.6081426439747855 1.0 0.9143019225250965 4 P48735 1 +Metapathway biotransformation phase i and ii 0.4664683602626377 0.5091506112170308 0.6106466586151924 1.0 0.915189109842718 19 Q86UY6,Q16850,P21964,P07099 4 +Envelope proteins and their potential roles in edmd physiopathology 0.460428078114443 0.4998197500909238 0.6172020026570411 1.0 0.922654014176087 15 Q02750,P50402,P42166,Q9Y2U8,P33176,Q14739,P42167,O94901 8 +Ferroptosis 0.460022373631922 0.4695890295520948 0.6386486640195588 1.0 0.923390951017189 22 P45880,P04792,P09601,Q9Y277 4 +Translation inhibitors in chronically activated pdgfra cells 0.4523296585620902 0.4636381590625877 0.6429070102645276 1.0 0.923390951017189 15 Q02750,P31751,Q53EL6,Q15418 4 +Kit receptor signaling pathway 0.4404255568634725 0.4240904196341612 0.671499872123622 1.0 0.9282271059197098 13 P51812,Q06124,Q15418 3 +Cardiac progenitor differentiation 0.4149466192170832 0.4174059263366825 0.6763815208344395 1.0 0.9282271059197098 2 Q16539 1 +Adipogenesis 0.4383515750677964 0.4152563269296279 0.6779542684874331 1.0 0.9282271059197098 13 P43490 1 +Regulation of sister chromatid separation at the metaphaseanaphase transition 0.4203679398997801 0.3790681388860433 0.7046372652738255 1.0 0.9450893573520468 8 O60216,O43684,Q9UJX6,O60566 4 +Head and neck squamous cell carcinoma 0.4243616408720922 0.378869105912901 0.7047850668307925 1.0 0.9450893573520468 10 Q13131,P11802,P62942,P42345,P31751 5 +Il5 signaling pathway 0.4141764757030992 0.3545944208860394 0.7228934563979403 1.0 0.9532589605272987 8 Q06124,Q15418 2 +Nrp1triggered signaling pathways in pancreatic cancer 0.4054885942406725 0.3297299194219842 0.7416040444608429 1.0 0.967884120387648 7 P31751 1 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.3881766381766367 0.2951136036459236 0.767907098074851 1.0 0.9868279812979444 4 P08069,P42345,P49770 3 +Interleukin11 signaling pathway 0.3996224028955533 0.2906627247480335 0.7713092826118781 1.0 0.9890311588852532 9 Q06124,Q15418 2 +Myometrial relaxation and contraction pathways 0.4095360291194413 0.2667593509276204 0.7896544536548378 1.0 1.0 18 Q13555,P16615,P78417,P05771,P63218 5 +Physicochemical features and toxicityassociated pathways 0.3962515311946802 0.2623389166752882 0.7930601611744885 1.0 1.0 11 Q02750,P35080 2 +4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression 0.3711865648237736 0.226534332949811 0.8207858593477686 1.0 1.0 5 Q02750,Q13131 2 +Pancreatic adenocarcinoma pathway 0.3816703731683695 0.1956799728740579 0.8448606606945548 1.0 1.0 13 Q02750,P31751,P30086 3 +Nephrotic syndrome 0.3784064481831825 0.191853042050822 0.8478573210706921 1.0 1.0 12 Q7Z4L5,O75844 2 +Chromosomal and microsatellite instability in colorectal cancer 0.3806029539716992 0.1849912323244534 0.8532359124781654 1.0 1.0 14 Q02750,P31751,Q9UJX6 3 +Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3606662261353366 0.1745827150720978 0.861407531360169 1.0 1.0 7 O14964,P31943 2 +Pi3kaktmtor vitd3 signaling 0.3467426130295522 0.1702258150070394 0.8648325505509771 1.0 1.0 3 P42345,P00338 2 +Egfegfr signaling pathway 0.3963534908882191 0.1682667385679299 0.8663734395139597 1.0 1.0 37 P00403,Q06124,Q15418,P40818,Q96J02,P51812,P30086 7 +Glycogen synthesis and degradation 0.3754528370704165 0.1676239300219547 0.8668791441328314 1.0 1.0 14 P13807,P46976,P30154 3 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.3729146835915535 0.1662940757316813 0.8679255280181091 1.0 1.0 13 P08670,P04792 2 +Preimplantation embryo 0.3545370029168995 0.1560091527774366 0.8760258066893865 1.0 1.0 7 Q99729,Q92945 2 +Ciliopathies 0.379076984832242 0.1484120710490173 0.8820175742480274 1.0 1.0 19 Q13432,Q7Z4L5,O43924 3 +Cardiac hypertrophic response 0.3545644589663043 0.1477594162113204 0.8825326388566654 1.0 1.0 8 P31751 1 +Tolllike receptor signaling pathway 0.3564372375496136 0.1373078501185063 0.890787465711685 1.0 1.0 10 Q02750,P31751 2 +Ranklrank signaling pathway 0.3589584848443814 0.1296930260181463 0.8968093003967608 1.0 1.0 12 Q02750,Q15750,P42345,O95340,P31751 5 +Gpr143 in melanocytes and retinal pigment epithelium cells 0.3266903914590779 0.1249942404194534 0.9005281100594982 1.0 1.0 2 P05771 1 +Genes related to primary cilium development based on crispr 0.3615843001603949 0.1165345873435989 0.9072288760868804 1.0 1.0 15 O95684,Q7Z4L5 2 +Nongenomic actions of 125 dihydroxyvitamin d3 0.3371942719539679 0.1156073799979078 0.9079637137364174 1.0 1.0 6 Q13555 1 +Ethanol effects on histone modifications 0.345701034605784 0.1142834291842813 0.9090131180253156 1.0 1.0 9 Q9H9T3,P04818,Q92769,Q99707,O14929,Q13547,P00374,P05091 8 +Somatroph axis gh and its relationship to dietary restriction and aging 0.3228907084371726 0.1062153608622543 0.91541148368362 1.0 1.0 3 P08069,P42345 2 +Melanoma 0.3363233698006006 0.0891496192923017 0.9289630038551212 1.0 1.0 9 Q02750,P31751 2 +Calcium regulation in cardiac cells 0.3656135121839495 0.0877056793268826 0.9301106055717788 1.0 1.0 22 Q13555,P62942,P16615 3 +Angiopoietinlike protein 8 regulatory pathway 0.3628724055747799 0.07902676921058 0.9370113308935044 1.0 1.0 22 Q02750,P31751,Q15418,P13807,P49327,P51812 6 +Embryonic stem cell pluripotency pathways 0.3283289955649748 0.06914690248657 0.9448726875574482 1.0 1.0 9 Q02750,P31751,Q06124 3 +Tumor suppressor activity of smarcb1 0.3290470333342035 0.0633462352909334 0.949490799228086 1.0 1.0 10 Q969G3 1 +Sarscov2 innate immunity evasion and cellspecific immune response 0.3286933565727162 0.0624924372800943 0.9501706843463782 1.0 1.0 10 P35613,Q6PKG0 2 +Intracellular trafficking proteins involved in cmt neuropathy 0.3245627224441498 0.0527163323342248 0.957957925798934 1.0 1.0 10 P04792 1 +Glioblastoma signaling pathways 0.3376871139962634 0.049474328014152 0.9605412954162738 1.0 1.0 15 Q02750,P31751,P11802 3 +Glycerolipids and glycerophospholipids 0.2918149466192245 0.0480395023863201 0.9616847605823988 1.0 1.0 2 O96017 1 +Photodynamic therapyinduced unfolded protein response 0.3208422555317693 0.0442202955005855 0.9647288044060364 1.0 1.0 10 P27797,P23381,Q13217,Q9UBS4,P05198,Q9BY44,P08243,P14625,O43776 9 +Aryl hydrocarbon receptor pathway wp2873 0.2928393302458126 0.0256878610822175 0.9795063061165744 1.0 1.0 5 P07900,Q15185,Q16543,Q01650 4 +Mecp2 and associated rett syndrome 0.3406587992898595 0.0204417215345995 0.9836910018230338 1.0 1.0 21 P52597,P67809,P35637,P31943,Q13451 5 +Transsulfuration and onecarbon metabolism 0.3255602469049229 0.0136799184767296 0.989085344683845 1.0 1.0 16 O43865 1 +Interleukin1 il1 structural pathway 0.2902746491463026 0.0134811367347594 0.9892439349413388 1.0 1.0 6 Q02750 1 +Synaptic signaling pathways associated with autism spectrum disorder 0.2978201077570602 0.0122301446068824 0.9902419997035414 1.0 1.0 8 Q13131,P31751 2 +Hepatitis b infection 0.3344994019940636 0.0104450270079311 0.991666225747314 1.0 1.0 20 Q02750,Q15750,P49327,P31751,Q9Y277 5 +Complement system 0.2953017162090692 0.0007285992834935 0.999418661932123 1.0 1.0 9 Q99829 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5a1683ec4bc6b85da1e2978f95b8f4a9f7dc42a8 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanomaterialinduced inflammasome activation", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selective expression of chemokine receptors during tcell polarization", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AAR2", "AARS", "AASS", "ABCB1", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "AMOT", "ANAPC1", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APEX1", "APLP2", "APMAP", "APPL1", "APRT", "ARCN1", "ARF4", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL6", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG9A", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "B3GALT6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BLVRA", "BLVRB", "BPTF", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "C1QBP", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPZB", "CARM1", "CASK", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CENPF", "CEP170", "CEP44", "CEPT1", "CERS2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHKA", "CHMP5", "CHMP6", "CHORDC1", "CHTF18", "CIP2A", "CKB", "CLASP1", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT9", "CNP", "COA3", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT2", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DARS", "DBNL", "DCAF1", "DCAF7", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDAH2", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DOCK1", "DPM1", "DPYSL2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERCC2", "ERCC3", "ERCC4", "ERI1", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC2", "EXOSC7", "EXOSC9", "EZR", "F11R", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FKBP10", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GCC2", "GCDH", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GIGYF2", "GLA", "GLB1", "GLRX", "GLS", "GLUD1", "GM2A", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GRB2", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIRIP3", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF2", "IMP3", "IMPAD1", "IMPDH2", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ITCH", "ITGB1", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIF1B", "KIF22", "KIF23", "KIF2C", "KIF4A", "KIF5B", "KLC1", "KMT2A", "KPNA1", "KPNA4", "KPNB1", "KTN1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG3", "LIN28B", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LPGAT1", "LRP1", "LRPPRC", "LRRC59", "LRSAM1", "LRWD1", "LSM2", "LSM4", "LSM7", "LSS", "LTA4H", "LZTFL1", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARS", "MAT2A", "MAT2B", "MAU2", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDC1", "MDH1", "MDH2", "ME2", "MECP2", "MFAP1", "MFN2", "MGST3", "MIA3", "MIF", "MKI67", "MMADHC", "MOGS", "MORF4L1", "MOV10", "MPDU1", "MPG", "MPI", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTMR6", "MTOR", "MTR", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1C", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NCAPG", "NCBP1", "NCDN", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NONO", "NOP2", "NPC1", "NPC2", "NSDHL", "NSF", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OXCT1", "P3H1", "P4HA1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA6", "PDLIM5", "PDS5A", "PDS5B", "PEBP1", "PECR", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIBF1", "PIGT", "PIK3C2A", "PIK3R4", "PKM", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PMPCA", "PNP", "PNPT1", "PODXL", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "QPRT", "RAB10", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RBPJ", "RCC1", "RCN1", "RDX", "RECQL", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RTCB", "RTN3", "RTN4", "RUVBL1", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SARS", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDHA", "SDHB", "SEC13", "SEC14L2", "SEC23A", "SEC23B", "SEC24A", "SEC24C", "SEC31A", "SELENBP1", "SEPT11", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3GL1", "SH3GLB1", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35B2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOD2", "SORT1", "SPEN", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STIP1", "STMN1", "STRAP", "STUB1", "STX4", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TAF5", "TALDO1", "TAOK1", "TARDBP", "TBC1D4", "TBCA", "TBK1", "TBL2", "TCF20", "TCP1", "TECR", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFRC", "THRAP3", "TIGAR", "TJP1", "TK1", "TKT", "TLN1", "TMED10", "TMEM43", "TMOD3", "TMPO", "TMPO", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRIP4", "TRMT2A", "TRRAP", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC21B", "TTC26", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TXNDC5", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE3A", "UBR5", "UBTF", "UCHL5", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS33A", "VPS4A", "WAPL", "WARS", "WDHD1", "WDR1", "WDR5", "WFS1", "WNK1", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ACAT2", "ACOX1", "ACOX3", "ACTN4", "AGPAT1", "AGPS", "AHCYL1", "AIFM1", "AKT2", "ALDH2", "ALDH3A2", "ANAPC2", "ANXA1", "ARHGEF7", "ARIH2", "ASNS", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "BSG", "BUB1B", "BUB3", "CALR", "CAMK2G", "CDC37", "CDK4", "CDKAL1", "CEPT1", "CERS2", "CHEK2", "CLPTM1L", "COA3", "COMT", "COX15", "COX2", "COX4I1", "COX7A2", "COX7C", "CPNE1", "CPT2", "CSTB", "CTNNB1", "CUL5", "CYB5B", "CYFIP1", "CYP51A1", "DHCR24", "DHFR", "DIABLO", "DNAJB11", "DNAJC3", "EI24", "EIF2A", "EIF2B2", "EIF2S1", "ELP3", "EMD", "EPHX1", "FASN", "FDFT1", "FGFR1OP", "FKBP10", "FKBP1A", "FKBP5", "FOXRED1", "FUS", "GNA13", "GNG5", "GSTO1", "GYG1", "GYS1", "HAT1", "HDAC1", "HDAC2", "HGS", "HLA-B", "HLA-C", "HMOX1", "HNRNPAB", "HNRNPF", "HNRNPH1", "HSP90AA1", "HSP90B1", "HSPB1", "ICMT", "IDH2", "IFNGR1", "IGF1R", "ITCH", "KDM1B", "KDSR", "KHSRP", "KIF5B", "KMT2A", "LARP1", "LBR", "LDHA", "LEMD3", "LMAN1", "LPGAT1", "LSS", "MAP2K1", "MAP2K4", "MAPK14", "MARC2", "MCL1", "MSMO1", "MTDH", "MTMR6", "MTOR", "MTR", "NAA40", "NAMPT", "NAP1L1", "NARS", "ND1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NFATC2IP", "NPC1", "P3H1", "P4HA1", "PAPSS2", "PCBP2", "PCNA", "PDCD4", "PDE6D", "PEBP1", "PECR", "PFDN5", "PFDN6", "PFN2", "PHGDH", "PPP2R1B", "PRKAA1", "PRKCB", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PSME3", "PTGES2", "PTGES3", "PTGR2", "PTPN11", "RAD21", "RPN1", "RPRD1B", "RPS6KA1", "RPS6KA3", "RTN3", "RTN4", "SCAMP2", "SCO1", "SCO2", "SDHB", "SGPL1", "SLC25A15", "SLC25A20", "SLC25A4", "SLC25A6", "SLC7A5", "SMARCE1", "SMYD3", "SPTLC1", "SQLE", "STAT1", "SUN1", "TAB1", "TBC1D4", "TMPO", "TP53", "TPM1", "TSPO", "TTC19", "TTC21B", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TYMS", "UNC119", "UQCR10", "UQCRFS1", "UQCRQ", "USP8", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "WARS", "YBX1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..15f802caf6af65652341957c3b7286520a1d9511 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "er"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..420b2d7427ae88dcd2d583b11c020bb8388f5c79 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b985841aecca7e629af0edee0fd86a2bb1b3e38fb241bae55e3ad7cc6be4ac92 +size 194537 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7bcf989469f51c947374b6441f27ebbdd9de6c3e --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "vesicles"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c33c2850c88d1aa7ebbb85087b4da9196d0051d7 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d433d3184b9f58eaefcddd94b588ef0cb5b1c30961b25b102cc5d48c6981abe +size 128244 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f6147a3e33db38ebdefbf00d232d949833e902a7 --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:179ee4669ae768173307e7be80736ab7f325fb6707b6fe1245ebc937f9f1ba7a +size 137790 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..1db1994aa731493680ebbb1afbfce52d37d41267 --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d94797e233f04485c014459b7946dd345f23c008225ae914791873760eb8e4f +size 63300 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..100cf607105604cc3c4bebdda163f52d0be8f152 --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 30 78 2.863825592139053 0.004185584024231 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 4.371684809409929e-08 0.0043644807500144 7.726867136605417e-06 2.771629741540472e-07 2.883904987384341e-11 +mitochondria 3 10 2.0075790706743373 0.04468804045065 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 0.0005891399824163 0.0016377422378922 0.0065261066260236 0.0001960616495152 0.0027630263410089 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..81a5800bac7da9e5a406da19b9075c7f82447b39 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 88.23529411764706 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..91ec1fe5872e6d35d9e3bba4138dbb71812a6f8e --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f55097b093f79cc1825ebb8aa96f7a1e513f6406 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.5677960882588186 2.863825592139053 0.004185584024231 0.0688214692252958 0.0711549284119284 78 O00264,Q9NQC3,Q06136,P46977,Q15041,Q15392,Q07065,Q9Y487,O15269,Q8NF37,O15173,Q9P2W9,Q9BZF1,P49755,Q16850,P04843,Q96N66,Q9Y5M8,Q13190,Q9NTJ5,Q9UKR5,Q96A33,P48449,Q96GC9,P27824,Q15363,O96005,O95470,Q9Y6K0,Q9UM00 30 +mitochondria 0.7719797238418347 2.0075790706743373 0.04468804045065 0.5403061960347617 0.298280462601893 10 P45880,P21796,Q9Y277 3 +vesicles 0.3077583655530853 0.9138631326652392 0.360788767922849 0.9995034594043518 1.0 156 O00264,O14964,Q06136,Q9UKG1,P61160,P05023,Q15392,P20020,Q9Y678,Q8IZA0,O15269,P53992,O00429,Q93050,Q8NF37,O15258,P42356,Q6RW13,O15173,Q9Y5X3,Q5VW38,P30825,Q9BZF1,P53985,P49755,P04439,Q8IXU6,Q9UKR5,Q96L92,P48449,Q15363,O96005,O95470,O15027,Q969T9,P55735,Q9Y6K0,O14976,P31751,Q9UM00,Q01650 41 +focal_adhesions 0.4916552036406724 0.7133508789260273 0.4756286610032449 0.9999828658689928 1.0 5 Q14155 1 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..aefbbc757966553f68c8b6af6466792672cef980 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGTRAP", "AHCY", "AHSA1", "AKAP12", "AKAP8L", "AKR1A1", "AKT2", "ALDH9A1", "ANAPC16", "ANAPC2", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "APLP2", "APPL1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARPC2", "ARPC3", "ATG9A", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOP1", "BPNT1", "BRD2", "BTF3", "BUB1B", "BYSL", "C1orf123", "CAD", "CALD1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDS2", "CEP170", "CEPT1", "CHEK2", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP6", "CHMP7", "CKAP2", "CKAP2L", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLINT1", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COMMD4", "COPA", "COPB2", "COPG1", "COPG2", "COPZ1", "CORO1C", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DRG1", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "EBNA1BP2", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC4", "EMC7", "EMG1", "ENO1", "EPS15", "ERG28", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNL2", "GNL3", "GORASP2", "GPR107", "GRB2", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HMGN2", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPB11", "HSPBP1", "HSPH1", "HUS1", "IDI1", "IGF1R", "IGF2BP1", "IGF2BP3", "ILF3", "IMP3", "INTS14", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IST1", "KDSR", "KIAA0319L", "KIAA0368", "KIF11", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LAMP1", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LMAN1", "LMNA", "LMNB1", "LPCAT1", "LSM14A", "LSS", "LTV1", "MAP2K1", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MBOAT7", "MDH1", "MECP2", "MED24", "MED4", "MFN1", "MFN2", "MIF", "MKI67", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTOR", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO6", "NANS", "NAPA", "NCAPH", "NCKAP1", "NCL", "NCLN", "NECAP2", "NEK9", "NHP2", "NIFK", "NOL10", "NOL11", "NOM1", "NONO", "NOP2", "NOP58", "NPM1", "NSA2", "NSDHL", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIN4", "PKM", "PKN2", "PLK1", "PMPCA", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "PPM1G", "PRKAA1", "PRKACA", "PRKDC", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTGES3", "PTK7", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB23", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB7A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAN", "RANBP1", "RANBP2", "RANBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM8A", "RBMX", "REEP5", "RER1", "RHOG", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAR1A", "SARS", "SBDS", "SCAMP2", "SCAMP4", "SCD", "SCFD1", "SCYL2", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SLC16A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC2A1", "SLC35F2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX9", "SPTLC1", "SPTLC2", "SQSTM1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIP1", "STT3A", "STT3B", "STX12", "STX18", "STX5", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TAOK1", "TARDBP", "TCF25", "TCOF1", "TFRC", "TIA1", "TJP1", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM24", "TRIM28", "TRIM33", "TRMT1L", "TRRAP", "TSG101", "TSR1", "TUBB4B", "U2AF2", "U2SURP", "UBA1", "UBE2M", "UBTF", "UGDH", "UPF1", "USP10", "USP36", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS25", "VPS29", "VPS33A", "VPS35", "VPS4A", "VRK3", "WAPL", "WBP2", "WDR12", "WDR3", "WDR46", "WDR75", "WNK1", "XPO1", "XPO4", "XPO5", "XPOT", "YIPF5", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326", "ZYX"], "leading_proteins": ["ACTR2", "AGTRAP", "AKT2", "APPL1", "ARHGEF7", "ARL6IP1", "ATP1A1", "ATP2B1", "ATP6V0A1", "ATP6V0A2", "CANX", "CCDC47", "CEPT1", "CKAP4", "CLPTM1", "COPG1", "CYP51A1", "DHCR24", "DNM1L", "ERG28", "GAK", "GPR107", "HGS", "HLA-A", "KDSR", "KIAA0319L", "LPCAT1", "LSS", "MBOAT7", "OSBPL8", "PGRMC1", "PGRMC2", "PI4KA", "RER1", "RPN1", "RTN4", "SACM1L", "SEC13", "SEC16A", "SEC24C", "SGPL1", "SLC16A1", "SLC35F2", "SLC7A1", "SLC7A5", "SNX27", "SNX5", "SPTLC1", "SRPRB", "STT3A", "STX18", "STX5", "TMCO1", "TMED10", "TMED2", "VDAC1", "VDAC2", "VDAC3", "VMP1", "WBP2"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json b/panther_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..853d8cfd8129bb407e06fe9e11c50722cd137624 --- /dev/null +++ b/panther_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "transmembrane signal receptor", "1": "oxidase"} \ No newline at end of file diff --git a/panther_protein_class/advanced/plot_0.png b/panther_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f199f3e51c861aa3904a817418cca860cee36d46 --- /dev/null +++ b/panther_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b4973ee13f7460db4cacabe63d76607dc68039fe0e5a21387c41c228c27b55e +size 190801 diff --git a/panther_protein_class/advanced/plot_1.png b/panther_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4981107234ef2a5baab2328fc3b4364545dcb786 --- /dev/null +++ b/panther_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:083e9e684d68c071b63d30bfa89a2314ea6612c0d14ca744d2b105b16354b2da +size 194425 diff --git a/panther_protein_class/basic/idx2term.json b/panther_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..37edd67a23a7aeea9bf1f74903da0b3474ea135f --- /dev/null +++ b/panther_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "transmembrane signal receptor", "1": "oxidase", "2": "acyltransferase", "3": "primary active transporter", "4": "oxidoreductase", "5": "transporter", "6": "ATP synthase", "7": "metalloprotease", "8": "protein modifying enzyme", "9": "chaperone", "10": "dehydrogenase", "11": "protease", "12": "scaffold/adaptor protein", "13": "glycosyltransferase", "14": "transferase", "15": "kinase"} \ No newline at end of file diff --git a/panther_protein_class/basic/plot_0.png b/panther_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2a3700e8c8a961d30e7902477be5eefd59ccfd1d --- /dev/null +++ b/panther_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c34dfeabec219ff457c417fad92012dcf283f5956c06249674cbf39788baf22a +size 140518 diff --git a/panther_protein_class/basic/plot_1.png b/panther_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9c7cf65f4b52ec3ee48c74acf93332bb68d7506d --- /dev/null +++ b/panther_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc6efb92a510a0b83a62c1da37b92ee7be8c13ee85d1b2a4e548aed5adfbd834 +size 130270 diff --git a/panther_protein_class/basic/plot_10.png b/panther_protein_class/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..a2aa051c42dc248acfb7fab7267aa06fde912fd8 --- /dev/null +++ b/panther_protein_class/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2cdbcf48da083edffca0d316a930c10be135a5dc5aee43f922a0f20458a3e843 +size 146024 diff --git a/panther_protein_class/basic/plot_11.png b/panther_protein_class/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..abde0dcf91fcdcc068c4362fb06e4d3c3ca9b3ac --- /dev/null +++ b/panther_protein_class/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d5dde47ef517f7f300bde93dac65a1c885ff60ae744d3f18db7727c532f43762 +size 140635 diff --git a/panther_protein_class/basic/plot_12.png b/panther_protein_class/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..20ca5200d8b7bba373e2c4d31a96a73fd4cbd391 --- /dev/null +++ b/panther_protein_class/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3cd9dfd658e01b23935c2867bb6ef3f5848b81a529acd974f227998f562960e2 +size 149687 diff --git a/panther_protein_class/basic/plot_13.png b/panther_protein_class/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..42f101d9e0be39e7d72b0e0c5c1009b95da89700 --- /dev/null +++ b/panther_protein_class/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:342d803da9d6de68a73514d73dfdc1723b883939bcad4b59bda6bf20630c7c4e +size 144439 diff --git a/panther_protein_class/basic/plot_14.png b/panther_protein_class/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..a1e3fa85bb8828d25be08d344cfd7ebd47abefec --- /dev/null +++ b/panther_protein_class/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:386c516e759ab15c58d34a3faacbae4b49ce2a65219001de1c6b3d4ac82b1829 +size 145915 diff --git a/panther_protein_class/basic/plot_15.png b/panther_protein_class/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..9141cf64f0db7a9bbd495953acc60be447bde923 --- /dev/null +++ b/panther_protein_class/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:351f420d2d11d321914139d0a9af3db0732514c0409711a9e9870519040c1bd8 +size 134808 diff --git a/panther_protein_class/basic/plot_2.png b/panther_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..1453c9a0927f042c012f46a8ee9bca58432f485a --- /dev/null +++ b/panther_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0604d468fabae38fa56fa4ee8d5638055a3a78a448f75e758dba01c7d14259a6 +size 133382 diff --git a/panther_protein_class/basic/plot_3.png b/panther_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..ed03def7c04123aecad34bb30f785ee6677b1c93 --- /dev/null +++ b/panther_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d1c28935affb45a7d6fb87dbd7eee0b1813edbd100acd5253b365ee39741d7df +size 135163 diff --git a/panther_protein_class/basic/plot_4.png b/panther_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..a97bf9ccedc87575397f7f7df82f81d133f98102 --- /dev/null +++ b/panther_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:46a04be06ffe23186f2a05521707856e1f1a9afb0433f71baae7ecabf13eec21 +size 134256 diff --git a/panther_protein_class/basic/plot_5.png b/panther_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..91cfcff60550b80a7960dbac48c6d549c48768c0 --- /dev/null +++ b/panther_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6890eddf3d0168fea7d533973240e38489a1d0a25394a3261c26eaaf6e02b733 +size 130143 diff --git a/panther_protein_class/basic/plot_6.png b/panther_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4bb9454106f9c5b25e2e4278557bf762eba305fe --- /dev/null +++ b/panther_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ec957d91e528ecf6a027428dc7984b7c36293962b9d1acc280b7f30b45d9a51a +size 133585 diff --git a/panther_protein_class/basic/plot_7.png b/panther_protein_class/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..57fd83625999c69bb8f624f516cb45e19904d36d --- /dev/null +++ b/panther_protein_class/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f74d0a7ddb76bb0f9da134f0936a439b4ddae6bfe595a2e4564d51b1cf49549d +size 137609 diff --git a/panther_protein_class/basic/plot_8.png b/panther_protein_class/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..6a1438df91a3ffcddafd162d0edec03d75860a48 --- /dev/null +++ b/panther_protein_class/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42583f046486565d90d5fe450c8e2df347422a8214863e69dc404b741b7acd56 +size 139131 diff --git a/panther_protein_class/basic/plot_9.png b/panther_protein_class/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..37dca875aab4c245c2bf593a945fe328fa0a7969 --- /dev/null +++ b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78d26195811a7966316705719bf34a036ea7872d3578d6f5c53324270740fc8a +size 139069 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..261a3944f573122b79b2d8bd0a72e46499b2e4d7 --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:494d42530856b8051a598109bdaa96de37de9f7cf6ac2b78d06100c707adf679 +size 76165 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5984dfc06a2014fdceefec7cb308bba1ed7a9341 --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +transmembrane signal receptor 6 8 2.56171095445718 0.0104157964098106 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.0013537832825369 1.0 0.0113667517638714 0.0232165330960884 0.1588595559179819 +mitochondrial carrier protein 4 6 2.4241555774420527 0.0153440304790823 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 0.0123366773007521 0.0595353304203936 0.1169218221283287 0.003279014583115 0.0002457979454447 +oxygenase 3 6 2.3952686406676613 0.0166081919232941 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.003748436319949 0.1071891284628969 0.0215793786244467 0.0191106391622076 0.0269295467729808 +calmodulin-related 4 9 2.346543993038728 0.018948429162015 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 1.622281536927146e-05 1.0 0.0016492758756177 0.0002756043574713 0.0010205277760807 +oxidase 7 13 1.9882048316535847 0.0467890408418949 5.111650485436893 13.890776699029129 1.1786899361665428 0.2351652471103072 2.6295852591466065 1.831549924215542 1.2715889014379809 0.2754701040210626 0.0703871957606151 0.1444128696349771 0.2709026461704186 0.0440381918347023 0.0001380057592112 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f3d76695e41668db1acbc60e13fc197d328b99db --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 154, + "title": "Average number of proteins per term", + "value": 12.753246753246753 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4b58e1cb101b36f1a9a73078f9c40f7d16b3996e --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a30e65db684a961e11c9dab8ab7212272c42d924 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,48 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +G-protein coupled receptor 0.980071174377224 2.9043181962964666 0.003680538900505 0.4332565956682225 0.1386374753663164 2 Q9NPR9 1 +tubulin 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.4603397396688415 0.1386374753663164 4 P07437,Q9BVA1,P68371 3 +voltage-gated ion channel 0.9154749384829308 2.6377731706557985 0.0083452381594479 0.7248831080036569 0.1386374753663164 4 P45880,P21796 2 +amino acid transporter 0.9052022725222468 2.595060949663963 0.0094574146330699 0.7685456631137069 0.1386374753663164 4 P30825 1 +transmembrane signal receptor 0.8975607188517711 2.56171095445718 0.0104157964098106 0.80060046417886 0.1386374753663164 8 O00264,P15260,Q8WUJ1,O15173,Q96GC9,Q99720 6 +mitochondrial carrier protein 0.8658845008577867 2.4241555774420527 0.0153440304790823 0.9075693942831816 0.1575320462519125 6 Q9Y6C9,Q70HW3,Q00325,Q9NZJ7 4 +oxygenase 0.8591668258580334 2.3952686406676613 0.0166081919232941 0.924160707772916 0.1598538472617057 6 Q16850,P09601,P30519 3 +calmodulin-related 0.8475360679997478 2.3465439930387277 0.018948429162015 0.947453599206589 0.1716504759382535 9 P80303,Q14257,O43852,Q9BPX6 4 +major histocompatibility complex protein 0.7759971509971415 2.0386036687360183 0.0414895987924042 0.9985347497197058 0.2218614724168609 4 P01889,P04439,P10321 3 +oxidase 0.7671172209169344 1.9882048316535852 0.0467890408418949 0.9993761069731796 0.225069156806174 13 O75880,P13073,O43819,Q15800,Q8NB78,P14406,Q6ZRP7 7 +DNA glycosylase 0.7569395017793565 1.965229972557336 0.0493876263980948 0.9995902364748692 0.225069156806174 2 P13051 1 +viral or transposable element protein 0.7313167259786639 1.8507178924506775 0.0642101486202888 0.9999635696814294 0.2672530510141752 2 Q9NUD5 1 +acyltransferase 0.6738164335149986 1.542660532031822 0.1229131627518942 0.9999999983073804 0.3839250035208392 15 Q99943,Q8NCC3,Q8NF37,Q92696,P23786,Q9BWD1,O15228,P49356 8 +primary active transporter 0.6683699880451605 1.5294655503747256 0.1261490729766377 0.9999999990420296 0.3839250035208392 21 Q9NS69,Q15388,P16615,Q9GZP9,Q8N4H5,Q9BUN8,Q6P4A7,O60888 8 +oxidoreductase 0.6205835678220846 1.43191788610204 0.1521673227813726 0.9999999999908848 0.3992945725855161 38 P00403,O14949,Q15067,O43676,O75306,O43169,O96000,O15254,O95831,Q8N4Q0,P16435,Q9Y6M9,Q9Y320 13 +secondary carrier transporter 0.6421176002814615 1.3920284071917932 0.1639137959165735 0.9999999999989366 0.3992945725855161 11 Q96ES6,Q9UBX3,Q8TB61 3 +esterase 0.6352385215351087 1.3791851231506873 0.1678376837159332 0.9999999999994847 0.3992945725855161 6 Q9NUJ1 1 +ATP-binding cassette (ABC) transporter 0.6332097451912732 1.376931511843863 0.1685334234938866 0.999999999999547 0.3992945725855161 5 P28288,O75027,P33527 3 +transporter 0.5402895567654734 1.337799084138719 0.1809619405317832 0.9999999999999556 0.4098255712043327 56 Q99595,O60830,O43772,Q567V2,P55735,Q8NFH4,Q9Y619,Q99805,Q8N1F7,Q9H2D1,Q9HD45,Q15070,P53985 13 +calcium-binding protein 0.6161361271243933 1.2831073210839974 0.1994544792212313 0.9999999999999988 0.438799854286709 7 P12429,P04083,P50995 3 +ATP synthase 0.6191723692554197 1.2740917933812683 0.2026308865090025 0.9999999999999992 0.4395092467941744 20 O75964,Q93050,P56385,P61421,P24539,P06576,P36542,P56134,Q9Y487 9 +methyltransferase 0.6152393752146113 1.261408503718085 0.2071617061080906 0.9999999999999996 0.4430958713978604 11 P21964,Q9BV86 2 +lyase 0.6032771551444881 1.2114391376938702 0.2257271472496718 1.0 0.4663976458594501 9 Q9UHG3 1 +guanyl-nucleotide exchange factor 0.5988584365002803 1.1951543489221657 0.2320267308645989 1.0 0.4663976458594501 8 Q14155,Q14C86 2 +translation factor 0.5970749941979978 1.192159212768025 0.233198822929725 1.0 0.4663976458594501 7 P51114,Q53EL6 2 +SNARE protein 0.5774456154363659 1.0868840014938663 0.2770880775776314 1.0 0.5333945493369405 9 Q9P2W9,Q13190 2 +metalloprotease 0.57599611948753 1.0617064240095198 0.2883689821032376 1.0 0.5367474501402705 25 Q9NY33,P55786,P52888,Q9UIQ6,Q5JRX3,Q9BYT8,O75844 7 +RNA methyltransferase 0.5687873179078891 1.0351184084129927 0.3006136166308746 1.0 0.5465002296513449 11 O75648 1 +protein modifying enzyme 0.5719375409571335 1.032923421322525 0.3016397371452228 1.0 0.5465002296513449 22 Q92791,O60725,Q15418,O75718,Q86X55,P51812,P13674 7 +protease inhibitor 0.5433692799155272 0.9364020617724946 0.3490662168136849 1.0 0.6078099537536209 7 P30086 1 +histone modifying enzyme 0.5388306383551118 0.8900581670713206 0.3734346537944404 1.0 0.6319663371905915 11 Q03164,Q9H7B4 2 +chaperone 0.4641239885843373 0.8420109129729336 0.3997818449944572 1.0 0.657581348481672 58 Q7KZN9,Q9Y2R0,Q13451,P62942,O95456,Q5TC12,Q8IXB1,Q99543,Q96KC8,P61758,O15260,P27824,P46379,Q15813 14 +ion channel 0.4957264957265059 0.7419749503931131 0.4581025127886686 1.0 0.7023266468646304 4 P51790,Q9C0H2,O00299 3 +actin and actin related protein 0.457784111150684 0.5628708875410325 0.5735228054332666 1.0 0.7956983066371447 5 P61163,O96019,Q9NZ32,P61160 4 +dehydrogenase 0.4089736381443067 0.5434712073659929 0.586805409854585 1.0 0.8060594980811537 62 Q3SXM5,P51648,O75874,O43175,Q9NZ01,P48735,P03886,Q709F0,Q96CU9,Q13423,Q92947 11 +protease 0.4695899245338433 0.5340737422985338 0.5932905156092247 1.0 0.8060594980811537 36 P49721,P60900,P28074,Q9BT78,Q15005,P28072 6 +heterotrimeric G-protein 0.4383903133903126 0.4908270309399808 0.6235487899110763 1.0 0.8181637850876848 4 P04899,P63218,Q14344 3 +transfer/carrier protein 0.4343935042241688 0.4125678474958975 0.6799232621033156 1.0 0.8628465303326269 11 Q9Y5M8 1 +protein-binding activity modulator 0.4190216342708359 0.4014332643641274 0.6881011627529614 1.0 0.8628465303326269 5 O14530,O14737 2 +hydrolase 0.4176646584778951 0.2850418312441907 0.7756120939590958 1.0 0.914880592988786 21 Q9Y3Z3,O43865,O60502,P07099 4 +scaffold/adaptor protein 0.3539113700045893 0.266376618926281 0.7899491703104242 1.0 0.914880592988786 67 Q9ULX6,Q9NZW5,O43823,Q5T2T1,Q9UQB8,Q8IZ81,Q9UKG1,Q96AG4,Q9UGP8,O14936,Q96L92,Q14168,P35613,Q7L576,Q9Y5X3,Q9Y679,Q5BKZ1,Q9UBB6 18 +zinc finger transcription factor 0.3672960456002762 0.2138255771304543 0.8306830785413162 1.0 0.9279581635289444 5 Q5VZL5,Q8WU90,Q9H1B7,Q9UGU0 4 +glycosyltransferase 0.3926949010314008 0.1819146144386628 0.8556497352020136 1.0 0.9279581635289444 22 P04843,Q10472,Q9BT22,P46977,P46976 5 +transferase 0.3847199757415729 0.1326085244243794 0.8945029904506061 1.0 0.9435168529410504 27 P53396,Q06203,P21266,P43490,Q96IJ6,Q9Y6K0,P37268,O95674,Q7LGA3,O43505 10 +kinase 0.3361891401421242 0.0456789115551843 0.963566172402084 1.0 1.0 15 Q8WVC6,Q9BRR6,P35790,Q53H12,P52789 5 +nucleotide phosphatase 0.2985393658710366 0.036147691324149 0.9711645949776871 1.0 1.0 5 Q9H857,P49902,Q9BX68,Q5TFE4 4 +C2H2 zinc finger transcription factor 0.2863247863247851 0.0222795377963843 0.9822249713042246 1.0 1.0 4 Q9Y467,O95785,Q7Z3K3 3 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b99907db1d943ce1692b883e181657afb17b78fb --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "zinc finger transcription factor"], "available_proteins": ["AACS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APPL1", "APRT", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGDIA", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6", "ARL6IP5", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "B3GALT6", "B4GAT1", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCLAF1", "BDH2", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CD47", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKN2AIP", "CDS2", "CEBPZ", "CEP170", "CEPT1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COA3", "COG4", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBR1", "DBT", "DCAF13", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDOST", "DEK", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DSG2", "DSP", "DSTN", "DTYMK", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GINS2", "GLA", "GLB1", "GLB1L2", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPR107", "GPR108", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGA2", "HMGCR", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUS1", "HUWE1", "IARS", "IARS2", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "ISOC1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0368", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KLC1", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LDHA", "LDHB", "LENG8", "LETM1", "LGALS3", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MANBA", "MAP1B", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MECP2", "MED24", "MED4", "METTL13", "METTL16", "MFAP1", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MKRN2", "MMS19", "MOB4", "MOGS", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCOA5", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NENF", "NF1", "NHP2", "NIP7", "NIPBL", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R4", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSMG1", "PSPC1", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QSOX2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM34", "RBM4", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNMT", "RNPS1", "ROCK1", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTN4IP1", "S100A11", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL2", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC35B2", "SLC38A1", "SLC7A1", "SLC7A5", "SLC9A6", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP23", "SNAP29", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAT1", "STAT3", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SWAP70", "SYNCRIP", "SYNGR2", "TAB1", "TAF15", "TAF2", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TECR", "TERF2IP", "TES", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TJP1", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM259", "TMOD3", "TMPO", "TMX2", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TP53", "TP53BP1", "TP53BP2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRAPPC4", "TRIM21", "TRIM24", "TRIM26", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBR1", "UBR4", "UBR5", "UBTF", "UCHL5", "UFL1", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNG", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VARS1", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VMP1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VRK1", "VRK3", "VTA1", "WARS", "WARS2", "WDHD1", "WDR1", "WDR33", "WDR82", "WIZ", "WNK1", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YEATS2", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZCCHC3", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF207", "ZNF326", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ABCD3", "ABHD10", "ACAD11", "ACAT2", "ACLY", "ACOX1", "ACOX3", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ADPGK", "AGK", "AGPAT1", "AHCYL1", "AIFM1", "AKAP8", "AKAP8L", "ALDH3A2", "ALG1", "ANXA1", "ANXA11", "ANXA3", "APPL1", "ARHGEF7", "ATP2A2", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATPAF1", "AUP1", "B4GAT1", "BAG6", "BAIAP2", "BSG", "CALU", "CANX", "CARM1", "CASK", "CDS2", "CEPT1", "CHKA", "CLCN3", "CLIC1", "COA3", "COMT", "COPS4", "COX15", "COX2", "COX4I1", "COX7A2", "CPT2", "CRTAP", "CUTA", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DCAKD", "DERL1", "DERL2", "DNAJC1", "DNAJC10", "DNAJC2", "DPP3", "ELMOD2", "EPHX1", "FDFT1", "FKBP1A", "FKBP5", "FNTB", "FOXRED1", "FXR1", "GALNT1", "GAPVD1", "GCDH", "GMPPA", "GNA13", "GNAI2", "GNG5", "GNPAT", "GPR108", "GSTM3", "GYG1", "HINT2", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HS2ST1", "HSDL1", "ICMT", "IDH1", "IDH2", "IFNGR1", "IRF2BPL", "KDM1B", "KMT2A", "LNPEP", "LPCAT1", "LRRC59", "MFSD3", "MGEA5", "MICU1", "MPP2", "MPP6", "MPP7", "MPV17L2", "MSMO1", "MTCH1", "MTCH2", "NAMPT", "NCDN", "ND1", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NLN", "NNT", "NPEPPS", "NT5C2", "NT5DC1", "NT5DC2", "NTMT1", "NUCB2", "NUP37", "NUP93", "OXA1L", "P3H4", "P4HA1", "PCYOX1", "PDCD4", "PDCD5", "PEBP1", "PGRMC1", "PGRMC2", "PHGDH", "PITRM1", "PLA2G15", "POGZ", "POR", "PPAT", "PSMA6", "PSMB2", "PSMB5", "PSMB6", "PSMG1", "QSOX2", "RABGGTA", "RCN2", "RPN1", "RPS6KA1", "RPS6KA3", "SALL2", "SAMHD1", "SCO1", "SCO2", "SEC13", "SEC63", "SFXN4", "SIGMAR1", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC35B2", "SLC7A1", "SMYD3", "SNX27", "SNX5", "SPCS2", "SRPRB", "STT3A", "STX18", "STX5", "SURF4", "TBCE", "TCF20", "TECR", "THOP1", "TIMM17A", "TIMM17B", "TM9SF2", "TM9SF3", "TMX2", "TOMM20", "TOMM22", "TOMM5", "TRMU", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TXNDC9", "UNG", "UQCRQ", "VBP1", "VDAC1", "VDAC2", "VMP1", "WIZ", "ZADH2", "ZC3H15", "ZCCHC3", "ZMPSTE24", "ZMYM4", "ZNF326"]} \ No newline at end of file diff --git a/pharos_dto/advanced/idx2term.json b/pharos_dto/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9de3bdc33047dba62d3c3c3c22943c56a729761b --- /dev/null +++ b/pharos_dto/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter", "1": "Oxidoreductase", "2": "SLC25 family of mitochondrial transporters"} \ No newline at end of file diff --git a/pharos_dto/advanced/plot_0.png b/pharos_dto/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..6dd38ee6a27bd46f928f95344adfb33f137a55b3 --- /dev/null +++ b/pharos_dto/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab51216e7f5e95886173894c8fe76b27090c72b49918d9589152d66ad43d486f +size 218351 diff --git a/pharos_dto/advanced/plot_1.png b/pharos_dto/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..fb9ab76a5c8827ac8e990663423b408d83246cbe --- /dev/null +++ b/pharos_dto/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9dadd8944efc807d12d7e7dc5f9bdc8d5642053094c156ac78c6df38be38e0e +size 216787 diff --git a/pharos_dto/advanced/plot_2.png b/pharos_dto/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..356dc5fde146c5d5534bd09811a9e8afbc8281eb --- /dev/null +++ b/pharos_dto/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f39b7e3f72330170261f078421e2464d92bb6fc9efaa7d7337818ba87ec63b93 +size 198923 diff --git a/pharos_dto/basic/idx2term.json b/pharos_dto/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..98d53ffeb9226f21af09e127beda9455f2ec2c55 --- /dev/null +++ b/pharos_dto/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter", "1": "Oxidoreductase", "2": "SLC25 family of mitochondrial transporters", "3": "Calcium-binding protein", "4": "Oxidase", "5": "Signaling", "6": "SLC superfamily of solute carriers", "7": "F-type and V-type ATPases", "8": "Glycosyltransferase", "9": "Transferase", "10": "Protease", "11": "Metalloprotease", "12": "Exoribonuclease", "13": "Reductase", "14": "Dehydrogenase", "15": "Epigenetic regulator", "16": "Enzyme modulator", "17": "Zinc finger transcription factor"} \ No newline at end of file diff --git a/pharos_dto/basic/plot_0.png b/pharos_dto/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..10879ee19d4e801d9ffc20ddcf4ced7917e4ec58 --- /dev/null +++ b/pharos_dto/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2a092ae1e7cdc5e2779d00917f7ec1ed55b14d57c2bd6d0931362c1411e696c +size 140694 diff --git a/pharos_dto/basic/plot_1.png b/pharos_dto/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9feb18bdf67cee021b5e0721889148d2f04ea75e --- /dev/null +++ b/pharos_dto/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7d6ecac696d7b407c3350ec72bb3cea613b344225a8f213e33b495e6fb90ff4 +size 138189 diff --git a/pharos_dto/basic/plot_10.png b/pharos_dto/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..a41608804e2b7d96cf46a6d79ed5499a03d9b735 --- /dev/null +++ b/pharos_dto/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f715540e68b23b67923aa524ba9104ef4b337f6d4fd7f8d1413978f750cad85 +size 141025 diff --git a/pharos_dto/basic/plot_11.png b/pharos_dto/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..8b530dc75a2a1faa74441a3fa0d11dae01f903f2 --- /dev/null +++ b/pharos_dto/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65c4de7ce417feea6ec65bbe4450aac4699371e52d477f274fb4d304f0efda6f +size 136878 diff --git a/pharos_dto/basic/plot_12.png b/pharos_dto/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..08a8c86feac377c20625ea7a6692b18453da6ff1 --- /dev/null +++ b/pharos_dto/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:563ad447df9a186688f3ced72ca5311190afc284efd3af7da771728af7fc068b +size 137243 diff --git a/pharos_dto/basic/plot_13.png b/pharos_dto/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..28388fa253f1c1276edcdd104580338e164d0367 --- /dev/null +++ b/pharos_dto/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ffa2851bb86c41b1983179eac6d86d64f223a2b38104c14d2083033b746e4f98 +size 141762 diff --git a/pharos_dto/basic/plot_14.png b/pharos_dto/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..4208c63a549aa33ddca2b4858bd604521da8167f --- /dev/null +++ b/pharos_dto/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3518b5d9b855c78ba8fd88477f0a0c1315edd3a8e9306fd8458345d7ce1aea2b +size 147339 diff --git a/pharos_dto/basic/plot_15.png b/pharos_dto/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..a1851bf9bd7a15d194a6e99bd88d56d5143a8cac --- /dev/null +++ b/pharos_dto/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f65e967fd7feab0ade22579ff6df756ac1ea844ee13feece8584d9b4a6e6cb4f +size 147045 diff --git a/pharos_dto/basic/plot_16.png b/pharos_dto/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..d001e908625510192905ecabccd9c4d7a9ae95cd --- /dev/null +++ b/pharos_dto/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c01e367e6301c615c916a7246aedcb0d99603a8a649f0f95d3b22579aff255c +size 144922 diff --git a/pharos_dto/basic/plot_17.png b/pharos_dto/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..872ef0b564f4a4bd090a4978f1a4926e7f48ba5f --- /dev/null +++ b/pharos_dto/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:842e7963657ac2569f5cb5dfc7b5bda8f4286a3f33a331b7f9151b242dc51acc +size 146101 diff --git a/pharos_dto/basic/plot_2.png b/pharos_dto/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..886a090a24af014ba6f1dc1237f99e4a492633ef --- /dev/null +++ b/pharos_dto/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b477f5086b8193161bd542a835b1e00728f6236193638a6e26b5d7164d28a22e +size 143395 diff --git a/pharos_dto/basic/plot_3.png b/pharos_dto/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..de420170b125f43e909971ae957413db87b8237c --- /dev/null +++ b/pharos_dto/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ec5afe6146c378fd916fe6b07608f76e87415689d6ae9722ace31cab9cc9ea8 +size 131174 diff --git a/pharos_dto/basic/plot_4.png b/pharos_dto/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..5926c1cfa83ac95251e1e13f97a7e878bc570f3e --- /dev/null +++ b/pharos_dto/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db55f17c9a26e6ba9a780fb4bf307e6850f0a1ee93ee1b67381af318001838c1 +size 127475 diff --git a/pharos_dto/basic/plot_5.png b/pharos_dto/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..3822af4107099d0ea09ebac4696e5ed8d22b1fa9 --- /dev/null +++ b/pharos_dto/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a058e590c3e5816e1af8ba294c2dbaf71f00a6a609e1947e5ae040e24784b1c8 +size 129864 diff --git a/pharos_dto/basic/plot_6.png b/pharos_dto/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..b83d2b69cfd6813f2c6c642a94de04b4dee50f0b --- /dev/null +++ b/pharos_dto/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c9995c74a4ebb5ed0f8f509426613a081ea977928622db3bda0a20c6cf16a8ad +size 138549 diff --git a/pharos_dto/basic/plot_7.png b/pharos_dto/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..8c5d7986b2d99ad6c812a2be040d982cdcf8ee97 --- /dev/null +++ b/pharos_dto/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:25488e226ebba667ff21814b9431e49f7147db7d411a65e9cb0b737b45e3a8ee +size 134413 diff --git a/pharos_dto/basic/plot_8.png b/pharos_dto/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b046e5977272cadf983d6491b0d19875d3382297 --- /dev/null +++ b/pharos_dto/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3b053abc3b3f8eac00edd865fdc336915d3673e5d070c755962debce422115a4 +size 136701 diff --git a/pharos_dto/basic/plot_9.png b/pharos_dto/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..fd88d1ae77cd14485fa2d73b78a1693e0d2e3538 --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b5b27ed5855e7c2f2629fe046122c8729d6074b0fe06ede64e63cdf054123e17 +size 138073 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..54dbff234f107360a6a41bf6a7f4c2cebf62a7d2 --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f66b4d8387162971e8844558156867a81bc8c39d2a1a70b5bb096438ea2b9a7 +size 409804 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2c7e52aa0fc3cb3b23f94ef562d1505fa00bb152 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter 43 168 3.040338437103907 0.0023631243936159 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 0.0587423121585141 0.1961623101425298 0.042244985540561 0.0033450279656374 2.2837637642916155e-05 +Oxidoreductase 28 110 3.0193137629883786 0.00253348002205 26.983009708737864 113.91747572815534 0.6392672411957 0.4324241122550336 10.483097938966514 7.235161275092307 1.3581321831066435 0.3819609334162012 4.187834328148188e-06 0.0170487305613109 3.0496966784221825e-05 3.1227581482175416e-06 5.058544245975961e-10 +V-type ATPase 1 8 2.312827769505632 0.0207321103546176 2.1310679611650487 7.861650485436893 0.6837768677711683 0.4403825457983871 1.5224232807818976 0.6368804388372676 0.8614537460314041 0.3094257476404272 0.1478851848182938 0.0550816697898294 0.1084298440104649 0.0323840811666381 0.1125747569923622 +Mitochondrial nucleotide transporter subfamily 3 8 2.159883570863039 0.0307816839129895 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0163228381361592 0.0021914548918381 0.0086772133501052 0.0491545726752397 0.0048822579474643 +SLC25 family of mitochondrial transporters 10 19 2.133132555493161 0.0329138538362077 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 0.0001171672450263 0.0130148737777564 0.0051311282902344 2.3610052517109835e-05 8.556622581523825e-07 +Methyltransferase 2 10 2.0206903148723883 0.0433118330450144 3.3980582524271843 13.567961165048544 0.2813543039069018 0.5594325728630254 2.032931814792849 2.1012577644512356 0.837855175821081 0.2997884915740831 0.3979570763548807 0.1644315705571846 0.3050454458143302 0.0624604060693988 0.1108133555378902 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c8e099e25cc588dd61110865222349bbdd7b88e5 --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 1848, + "title": "Average number of proteins per term", + "value": 3.1222943722943723 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..36021fb39a406abeffbc86ce1454cfcd4783f010 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d8f94e0afc02fc2982548e6d13a2ec46a41a8bd8 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,74 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.4439860792255209 3.040338437103907 0.0023631243936159 0.9873768388848504 0.0478963212182118 168 P12235,Q70HW3,Q9NZJ7,Q96ES6,Q9BQE5,Q8NEW0,Q9Y619,Q99805,P56134,Q9H2D1,P20020,Q9Y487,Q9Y678,P53992,Q93050,P24539,Q8NFH4,Q9P2W9,P06576,P30825,Q9UBX3,Q15070,P53985,P49755,Q15388,P16615,Q8IXU6,Q13190,Q9HC21,O43760,Q12907,Q8TB61,Q8N1F7,Q9UJS0,Q9HD45,P51809,Q15363,Q9Y3B3,O43772,Q00325,P55735,Q9Y6C9,Q01650 43 +Oxidoreductase 0.4797260342750801 3.0193137629883786 0.00253348002205 0.9907931898046232 0.0478963212182118 110 O75880,O43169,O43819,Q8N8N7,P03886,Q709F0,Q15392,P14406,P00403,Q9H7Z7,Q9NZ01,O95831,Q13423,O15260,Q6ZRP7,Q16850,Q9UDW1,O15254,P30837,Q9Y6M9,Q9BY49,Q15067,Q8TED1,O43175,Q15800,Q96CU9,Q14534,Q8N4Q0 28 +Tubulin 0.9743589743589742 2.8783759263548196 0.0039972848597742 0.999389837851838 0.0478963212182118 4 P07437,Q9BVA1,P68371 3 +SLC35 family of nucleotide sugar transporters 0.9298932384341676 2.702208281423522 0.0068880598654517 0.9999971641717468 0.0478963212182118 2 Q8TB61 1 +RSK subfamily 0.9227758007117488 2.673124551158895 0.007514834341864 0.9999991169266524 0.0478963212182118 2 Q15418 1 +RSK family 0.9227758007117488 2.673124551158895 0.007514834341864 0.9999991169266524 0.0478963212182118 2 Q15418 1 +Miscellaneous SLC25 mitochondrial transporters 0.9067615658363036 2.6073022716558003 0.0091258760078123 0.9999999561303224 0.0478963212182118 2 Q9Y6C9 1 +Mitochondrial amino acid transporter subfamily 0.8733172345047766 2.4610641813005976 0.0138525582872439 0.999999999993624 0.0541887103543728 4 O43772,Q9Y619 2 +SLC7 family 0.8640569395017904 2.4291462161830446 0.015134427405185 0.9999999999994238 0.0561614896481564 2 P30825 1 +Ca2+-ATPases 0.8540925266903988 2.3870205418069044 0.0169855421741054 0.9999999999999822 0.058462979252849 2 P16615 1 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8418708376787386 2.3306789207290985 0.0197702965098971 1.0 0.0628712692712059 3 P30825 1 +V-type ATPase 0.8401038776332133 2.312827769505632 0.0207321103546176 1.0 0.0647178039448199 8 Q9Y487 1 +Aspartic protease 0.8300430702465362 2.2798581947244956 0.0226161001899733 1.0 0.0684035239788393 3 Q5BJF2 1 +Protein arginine methyltransferase 0.8299626274656255 2.2753752069011544 0.0228834313698858 1.0 0.0686502941096574 4 Q86X55 1 +Mitochondrial nucleotide transporter subfamily 0.8055996738965642 2.159883570863039 0.0307816839129895 1.0 0.0812636455302923 8 Q9HC21,Q9H2D1,Q70HW3 3 +SLC25 family of mitochondrial transporters 0.7923985085228474 2.133132555493161 0.0329138538362077 1.0 0.0841283566933773 19 Q70HW3,Q9NZJ7,O43772,Q9HC21,Q9UJS0,Q00325,Q9Y619,Q9Y6C9,Q9H2D1,Q9UBX3 10 +Phospholipase 0.7915817276224526 2.1076175803712975 0.0350640816532121 1.0 0.0878027410503199 4 Q8N2A8 1 +Lipase 0.7915817276224526 2.1076175803712975 0.0350640816532121 1.0 0.0878027410503199 4 Q8N2A8 1 +SET domain 0.7777791502690388 2.0517162865082734 0.0401972430153438 1.0 0.0953476310162783 3 Q9H7B4 1 +Methyltransferase 0.7748367896646596 2.0206903148723883 0.0433118330450144 1.0 0.0992832611765589 10 Q08J23,Q9BV86 2 +Intracellular calcium-sensing protein 0.7469975011376863 1.892535816447399 0.0584196262336269 1.0 0.1180431220028897 12 P80303,Q14257,O43852,Q9BPX6 4 +Calmodulin 0.7469975011376863 1.892535816447399 0.0584196262336269 1.0 0.1180431220028897 12 P80303,Q14257,O43852,Q9BPX6 4 +Calcium-binding protein 0.7427016508697807 1.8770961203878056 0.0605049210459909 1.0 0.1204882479450336 15 O43852,Q9BPX6,P80303,P43307,Q14257 5 +Oxidase 0.71827879386007 1.772060911900172 0.0763844465541783 1.0 0.1404561763503697 19 O75880,Q15067,O43169,O43819,Q15800,O15254,Q709F0,O15260,P14406,Q6ZRP7 10 +Protein methyltransferase 0.7147425960424789 1.744963698610127 0.0809911881081095 1.0 0.1454302407143568 8 O96028,Q9H7B4,Q86X55 3 +Acyltransferase 0.7026426867575083 1.6884614508814209 0.0913226828882263 1.0 0.1556466350130034 8 Q92696,Q8NF37,P49356 3 +AGC group 0.699644351466514 1.677456360386551 0.0934532762039317 1.0 0.1581516981912691 7 P51812,Q15418 2 +Signaling 0.6978797831443094 1.6642726691467975 0.096057951611082 1.0 0.16065719672035 17 Q96PC5,O00264,Q07820,Q8IZ81,Q5JRA6,P42166,Q8WUJ1,P43490,Q99627,O15173,Q96GC9 11 +STE group 0.6841877494902812 1.615423051012753 0.1062191117227802 1.0 0.1706636782715378 5 Q7L7X3 1 +CDK1 subfamily 0.6768683274021344 1.6032605853936173 0.1088771344852161 1.0 0.1733031391289229 2 P06493 1 +CAMK group 0.6783811794410166 1.588443530826545 0.1121860806303725 1.0 0.1771964760725883 5 Q13555,O96017,O14936 3 +SLC superfamily of solute carriers 0.6390008236706846 1.5399203436318598 0.1235797712584954 1.0 0.1884285621169137 38 Q70HW3,P30825,Q8IXU6,Q9NZJ7,O43772,Q9HC21,Q01650,Q9UJS0,Q00325,Q8NEW0,Q8TB61,Q9Y619,Q9Y6C9,Q9H2D1,Q9UBX3,P53985 16 +F-type and V-type ATPases 0.6705769308867285 1.5267227841478843 0.1268299593473898 1.0 0.1915933546478823 15 Q93050,P56385,P24539,P06576,P36542,P56134,Q9Y487 7 +ATP-binding cassette transporter family 0.6565183678245435 1.4936976034233036 0.1352546752286061 1.0 0.2017357867816498 4 O75027,P33527 2 +Protease inhibitor 0.6564707831760654 1.4746986391585888 0.1402935821168665 1.0 0.2061102986387826 7 P30086 1 +Writer 0.6413606496673352 1.3946787787731654 0.163112727038162 1.0 0.2302370565611824 9 O96028,Q9H7B4,Q86X55 3 +Glycosyltransferase 0.6246363161373265 1.2992103026645074 0.1938717667616414 1.0 0.2579373829917302 15 P04843,Q10472,Q9BT22,P46977,P46976 5 +Transferase 0.3395133708781433 1.2328967560777668 0.2176142858888896 1.0 0.2784980611652826 114 Q08J23,Q92696,P21964,P23786,P46977,Q8N128,Q9BWD1,Q9NZW5,O15269,Q10472,Q9BV86,Q8NF37,P49356,P04843,Q96N66,Q9NQT4,Q14168,P46976,P53396,Q9BT22,Q13126,Q9Y6K0,Q9Y679 23 +Extracellular matrix glycoprotein 0.5740101538801601 1.1061025091197394 0.2686821528279994 1.0 0.3201656182298923 4 Q32P28 1 +Oxygenase 0.5756455823943857 1.1049089561428052 0.269199041248831 1.0 0.3204007933409193 5 Q16850 1 +SNARE protein 0.5774456154363659 1.0868840014938663 0.2770880775776314 1.0 0.3273596803266239 9 Q9P2W9,Q13190 2 +Protease 0.3227634374523254 0.9671655116754584 0.3334613000592545 1.0 0.3716745974122451 105 P67812,P52888,P42785,Q9UIQ6,Q06203,Q8TEY7,Q9NY33,P55786,P61978,Q96K76,P40818,Q9NZ08,Q5BJF2,Q8TCT9,O75844,Q96RU2,Q66K14,Q5JRX3,Q9BYT8,Q96FW1,Q92945 21 +F-type ATPase 0.5326501780782831 0.885784766287584 0.3757335202765322 1.0 0.4036950845761811 7 P36542,P56134,P24539,P06576 4 +Receptor 0.5324594889167295 0.8297023881326528 0.4067070709031599 1.0 0.4287476708665371 24 Q13432,A6NIH7,P15260,Q567V2 4 +Intracellular chloride channel (clic) family 0.4953736654804261 0.7615496369350376 0.4463288430493275 1.0 0.4659975717260776 2 O00299 1 +TK group 0.4866500533997882 0.7114169791273878 0.4768258804312135 1.0 0.4969961799418402 3 P08069,Q13308 2 +Phosphatase inhibitor 0.4936164430109378 0.704283941546793 0.4812559647803698 1.0 0.5013309035592578 7 Q99733,P55209 2 +Metalloprotease 0.5011940026647884 0.703311721546111 0.481861507462141 1.0 0.501678910304246 35 Q9NY33,P55786,P52888,Q9UIQ6,Q5JRX3,Q9BYT8,O75844 7 +Histone deacetylase 0.4573516859688129 0.5714252004435759 0.5677114507021672 1.0 0.5887378007281734 4 Q92769 1 +Actin and actin related protein 0.457784111150684 0.5628708875410325 0.5735228054332666 1.0 0.5944308157266835 5 P61163,O96019,Q9NZ32,P61160 4 +Phosphatase modulator 0.4593739601850943 0.5348044061042981 0.5927851159536965 1.0 0.6137069435755917 9 Q99733,P55209 2 +Heterotrimeric G-protein 0.4383903133903126 0.4908270309399808 0.6235487899110763 1.0 0.6446088433378315 4 P04899,P63218,Q14344 3 +CAMKL family 0.4330960854092557 0.49064156240297 0.623679984787902 1.0 0.6446088433378315 2 Q13131 1 +Eraser 0.4431231836094703 0.4812136982457263 0.6303646261696738 1.0 0.6507898486936073 7 Q92769,Q8NB78 2 +Exoribonuclease 0.4448804851944397 0.4721044568329783 0.6368522314428771 1.0 0.656753863675467 9 Q15024,Q06265,Q13868,Q8IV48,Q96B26,Q6L8Q7,Q9Y2L1,Q9NQT5 8 +Reductase 0.4557222131291131 0.4683675671496571 0.6395217572882264 1.0 0.6591389891068836 17 O95168,O95881,Q9H7Z7,Q9UDW1,Q15392,P00374 6 +Microtubule family cytoskeletal protein 0.4418683346570176 0.4005704798281645 0.6887363833667752 1.0 0.708283158854647 39 P07437,P68371,Q9BVA1 3 +Extracellular structure 0.4225513876484425 0.3795219424980103 0.7043003131657368 1.0 0.7234835901780331 9 Q32P28,O75718,Q92791 3 +Acetyltransferase 0.4244986075711752 0.3328850664083351 0.7392210424690373 1.0 0.7576708189033726 17 P23786 1 +Dehydrogenase 0.4017372383801179 0.3061675396860649 0.7594770859787134 1.0 0.778000917344048 53 Q9BY49,O43175,O75306,P54886,Q8N8N7,Q9NZ01,P03886,O95831,Q96CU9,P30837,Q13423,Q8N4Q0 12 +Epigenetic regulator 0.4190361124268765 0.2701342938560913 0.7870569398131275 1.0 0.8053605895762235 28 Q6PL18,Q92769,O96028,Q8NB78,O60678,Q16637,Q9H7B4,Q86X55 8 +Cellular structure 0.2653459796939079 0.2311358349590965 0.8172092764833199 1.0 0.8352891277329508 94 P07437,P68371,Q4ZIN3,Q9BVA1 4 +Decarboxylase 0.364898540405842 0.2260188598968475 0.82118675176949 1.0 0.8388906120895618 3 Q9UJ83,A1L0T0 2 +Translation initiation factor 0.396731851264024 0.2174682679137657 0.8278434337884599 1.0 0.845223572177389 18 P23588,O75153,P55010 3 +Ion channel 0.3563547246665844 0.1700313288013824 0.864985498554719 1.0 0.8787758116157892 6 Q4KMQ2,Q9C0H2 2 +HDAC class III 0.3227758007117477 0.1151399233203666 0.9083342160816752 1.0 0.9187748392550278 2 Q8IXJ6 1 +Bromodomain 0.3216957605985007 0.0855054352302021 0.9318595746096644 1.0 0.9420549747695076 5 P51532,Q6PL18,Q8WWQ0,P25440 4 +Enzyme modulator 0.2522078624997873 0.0511380412368674 0.959215523110868 1.0 0.9691800364728724 100 P04080,Q7L576,Q99733,Q15005,P55209,O95067,O60313,P30086,P46379 9 +Translation factor 0.3550415192381247 0.04511718135938 0.9640139066227392 1.0 0.9734960106223072 24 P23588,O75153,Q53EL6,P55010 4 +Ubiquitin-protein ligase 0.3289303475415054 0.0346620459292495 0.9723492256894132 1.0 0.9813770448247054 14 Q96PU5,Q9H000,Q96J02 3 +C2H2 zinc finger transcription factor 0.2863247863247851 0.0222795377963843 0.9822249713042246 1.0 0.9908033553330824 4 Q9Y467,O95785,Q7Z3K3 3 +Esterase 0.3015083692672048 0.0118360832712281 0.9905563923950358 1.0 0.9986624185193814 9 Q969T7 1 +Zinc finger transcription factor 0.286528866714179 0.0072752624536691 0.9941952316196674 1.0 1.0 6 Q7Z3K3,O95785,P41223,Q9Y467,Q8WU90 5 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..018a680898afa8429b384be491056416bec08a63 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3'-5' exoribonuclease 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L51, mitochondrial", "39S ribosomal protein L9, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S26", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-1", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-formyltetrahydrofolate cyclo-ligase", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "Acetoacetyl-CoA synthetase", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Activating signal cointegrator 1", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-CoA-binding domain-containing protein 5", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Apoptosis-stimulating of p53 protein 2", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beta-galactosidase", "Beta-galactosidase-1-like protein 2", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Beta-mannosidase", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Bromodomain", "Bromodomain-containing protein 2", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "Ca2+-ATPases", "Cadherin", "Calcium channel auxiliary subunit 2 types 1-4 (cca-2) family", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmodulin", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cathepsin B", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Chaperone", "Chaperonin", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 6", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Choline/ethanolaminephosphotransferase 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1C", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA repair endonuclease XPF", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC3", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 4", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dynein light chain Tctex-type 1", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endothelin-converting enzyme 1", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Eraser", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Flavin reductase (NADPH)", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-mannose 4,6 dehydratase", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogenin-1", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "High mobility group protein HMGI-C", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SMYD3", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Hydrolase", "Hydroxylase", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "INSR family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 1 receptor", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Interferon gamma receptor 1", "Interferon-induced, double-stranded rna-activated protein kinase", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KH domain-containing, RNA-binding, signal transduction-associated protein 3", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF14", "Kinesin-like protein KIF18A", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Lanosterol 14-alpha demethylase", "Large neutral amino acids transporter small subunit 1", "Large proline-rich protein BAG6", "Lariat debranching enzyme", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "M-phase phosphoprotein 8", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Mannose-6-phosphate isomerase", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1B", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light chain 6B", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 6", "N(G),N(G)-dimethylarginine dimethylaminohydrolase 2", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ domain-containing protein 11", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phospholipid-transporting ATPase IG", "Phospholipid-transporting ATPases", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphoribosyltransferase domain-containing protein 1", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable ATP-dependent RNA helicase DHX34", "Probable ATP-dependent RNA helicase DHX35", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable E3 ubiquitin-protein ligase makorin-2", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA N6-adenosine threonylcarbamoyltransferase", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRG1", "Protein LSM14 homolog A", "Protein NDRG3", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A11", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein Wiz", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c beta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Recombining binding protein suppressor of hairless", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Rho GDP-dissociation inhibitor 1", "Rho-associated protein kinase 1", "Rho-related GTP-binding protein RhoG", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p20", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC7 family", "SLC9 family of sodium/hydrogen exchangers", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Secretory carrier-associated membrane protein 4", "Selenide, water dikinase 1", "Selenocysteine-specific elongation factor", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase tao1", "Serine/threonine-protein kinase tbk1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serpin B6", "Serpin H1", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium-coupled neutral amino acid transporter 1", "Sodium/hydrogen exchanger 6", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Switch-associated protein 70", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptosomal-associated protein 23", "Synaptosomal-associated protein 29", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10B", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 8B", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "Targeting protein for Xklp2", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin reductase 2, mitochondrial", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription initiation factor TFIID subunit 2", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor CTCF", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 4", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Trypsin-3", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2B chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin polyglutamylase TTLL4", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type II cytokine receptor", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm4", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 33", "Ubiquitin carboxyl-terminal hydrolase 36", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Voltage-dependent calcium channel subunit alpha-2/delta-1", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 82", "WNK family", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YEATS domain-containing protein 2", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger and BTB domain-containing protein 10", "Zinc finger transcription factor", "Zinc transporter 7", "Zyxin", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase"], "available_proteins": ["AACS", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APLP2", "APOBEC3C", "APOL2", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC3", "ARPC4", "ASAH1", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATIC", "ATP11C", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "BAG6", "BAIAP2", "BCAP31", "BCAS2", "BCLAF1", "BLMH", "BLVRA", "BLVRB", "BOP1", "BPNT1", "BRD2", "BRIX1", "BUB1B", "BUB3", "BUD31", "BZW1", "BZW2", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC37", "CDC42", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKN2AIP", "CEBPZ", "CEP170", "CEPT1", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTOP", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNP", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRNKL1", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNND1", "CTPS1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBR1", "DBT", "DCAF13", "DCPS", "DCTN1", "DCTN2", "DDAH2", "DDB1", "DDI2", "DDOST", "DENR", "DERL1", "DERL2", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX34", "DHX35", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPH5", "DPM1", "DPP3", "DPYSL2", "DSG2", "DSP", "DTYMK", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC4", "ERH", "ERI1", "ERMP1", "ERO1A", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GINS2", "GLB1", "GLB1L2", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNPDA1", "GNS", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPR107", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSPT1", "GSR", "GSS", "GTF2F1", "GTF3C3", "GTF3C5", "GTPBP1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDI1", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHDRBS3", "KHSRP", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "M6PR", "MACF1", "MAGED2", "MAGT1", "MANBA", "MAP1B", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME2", "MECP2", "MFAP1", "MFN1", "MFN2", "MFSD3", "MFSD5", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MKRN2", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL51", "MRPL9", "MRPS11", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NCAPD2", "NCAPD3", "NCBP1", "NCL", "NCOA5", "ND1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA9", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NEDD4L", "NEK9", "NF1", "NHP2", "NIPBL", "NKRF", "NLN", "NME1", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSUN2", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDZD11", "PEBP1", "PECR", "PEPD", "PES1", "PEX14", "PEX19", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PIR", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNP", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP7", "PPA1", "PPA2", "PPAT", "PPIL1", "PPM1F", "PPM1G", "PPP1CA", "PPP1CB", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA1", "PRKACA", "PRKAG1", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD7", "PSMD8", "PSPC1", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM3", "RBM4", "RBMX", "RBMXL1", "RBPJ", "RCL1", "RCN1", "RCN2", "RDH11", "RDX", "RECQL", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIPK1", "RNASEH2A", "RNF14", "RNH1", "RNPS1", "ROCK1", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "S100A11", "SAE1", "SALL2", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT2", "SIN3A", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A6", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMYD3", "SNAP23", "SNAP29", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPTLC1", "SPTLC2", "SQLE", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAT1", "STAT3", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYNCRIP", "SYNGR2", "TAB1", "TAF15", "TAF2", "TAF6L", "TAGLN2", "TAOK1", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TECR", "TES", "TFIP11", "TFRC", "TGOLN2", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TJP1", "TK1", "TKT", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM259", "TMEM97", "TMOD3", "TMPO", "TNPO1", "TNPO3", "TOMM20", "TOMM40", "TOP1", "TP53", "TP53BP1", "TP53BP2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIP4", "TRMT6", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TXNRD2", "TYMS", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2L3", "UBE4A", "UCHL5", "UGGT1", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP19", "USP28", "USP33", "USP36", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VMP1", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VRK1", "VRK3", "WARS", "WDHD1", "WDR1", "WDR33", "WDR82", "WIZ", "WNK1", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YEATS2", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZFR", "ZMPSTE24", "ZMYM4", "ZNF207", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCC1", "ACAD11", "ACAT2", "ACLY", "ACOX1", "ACOX3", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "AIFM1", "ALDH18A1", "ALDH1B1", "ALG1", "ANO6", "APOL2", "ATAD2", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "AUP1", "BAG6", "BRD2", "BUD31", "CALU", "CAMK2G", "CARM1", "CASK", "CCNB2", "CDK1", "CEPT1", "CHEK2", "CLIC1", "CLUH", "COMT", "COPG1", "COPS8", "COX2", "COX7A2", "CPT2", "CRTAP", "CSTB", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DHCR24", "DHFR", "DIS3", "DPP3", "EIF4B", "EIF5", "ELMOD2", "ERAP1", "ERI1", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "FAM177A1", "FNTB", "FOXRED1", "GALNT1", "GNA13", "GNAI2", "GNG5", "GPX8", "GYG1", "HACL1", "HDAC2", "HM13", "HNRNPK", "IFNGR1", "IGF1R", "ILVBL", "ITCH", "KDM1B", "KHSRP", "LMAN2", "LNPEP", "LPCAT1", "MBOAT7", "MCL1", "MFSD3", "MIA2", "MIA3", "MICU1", "MKRN2", "MPP2", "MPP6", "MPV17L2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "NAMPT", "NAP1L1", "NAP1L4", "ND1", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4L", "NLN", "NNT", "NPEPPS", "NSD2", "NSUN2", "NT5C3B", "NTMT1", "NUCB2", "NUP37", "NUP93", "OPA1", "OTUB1", "OXA1L", "P3H1", "P3H4", "PDCD4", "PDE12", "PEBP1", "PECR", "PGRMC1", "PGRMC2", "PHGDH", "PHIP", "PITRM1", "PLD6", "POGZ", "PPAT", "PRCP", "PRKAA1", "PRMT3", "PTGES2", "PTGR2", "PTK7", "QSOX2", "RABGGTA", "RCN2", "RPN1", "RPS6KA1", "RPS6KA3", "SALL2", "SCO1", "SCO2", "SEC11A", "SEC13", "SEC24C", "SIRT2", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC7A1", "SLC7A5", "SMARCA4", "SMN1*", "SMYD3", "SPCS2", "SPTLC1", "SQLE", "SSR1", "STT3A", "STX18", "STX5", "SURF4", "SYNGR2", "TAOK1", "TBC1D9B", "TECR", "THOP1", "TM9SF2", "TM9SF3", "TMED10", "TMED2", "TMED7", "TMEM259", "TMEM97", "TMPO", "TOMM20", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TXNDC12", "UNC119", "UNC119B", "UQCR10", "USP28", "USP33", "USP47", "USP8", "VAMP7", "VMP1", "WIZ", "ZADH2", "ZC3H15", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5caa491b9aa6e04692523f9ba93639712ee5eb71 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9c9df8ea6b745cb3bf2cfbeef266157c6df09479 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66f99b680392ac888f9d6fe5c43c30cc4e7bc76868c7c3e0c34c2376463dd173 +size 202426 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8a1fdd7a413878380ac3bc59fc785bad9e9e1fdd --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tdark", "1": "Tclin", "2": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..b1804ededdf7eb0b288ef060309ed7fe6b69276a --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2fef5b8227dba7f995d1619840b676cdffb6ff53204cabf6e9a2b0f68c343d5b +size 131411 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..905837507171952d84e84f32367ff5b7690fe381 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27e557a03c67e964f8078f440611618fbc45272a9fbb47e727ca94ae0dc8c133 +size 128228 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..041aef69c2e065adaa813e8068384d541fa07aa8 --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f7fac65db4efe15216e5bfd4fcce9c954d8d63024f27b56852de571a9dd4af4 +size 133900 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3a71a3543ceac9b0fc49a300d4c3ab9134d679c3 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c19f46ac136adf9dad04159e460ed3a6d51914ce21804212aa5e2f1da65c56f +size 63404 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..26a69bba87e7b4d636b55c36e53bd382c71de593 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tdark 50 274 2.0802178282142667 0.0375055577228748 74.3131067961165 324.373786407767 0.5859664552431031 0.6577158703271868 20.515717939687796 49.369088361677456 1.229854636263473 0.4013924214985833 0.9784060630451272 0.5296573722165894 0.8640082370181309 0.999754037698828 0.9999999412689629 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..8fbb19de08ac6559008e710009d3f614e8c60c2a --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 702.75 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e5b352e52a670f7d98bdc8bf1d21107347d32838 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b431560f1724f2b4aef61f562dac8da79e06567b --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tdark 0.3460021493020352 2.0802178282142667 0.0375055577228748 0.1417912823196948 0.1135992449501603 274 O60830,Q96E39,Q6UW68,Q969T7,Q96ES6,Q9HD20,Q92696,Q8N4H5,Q1KMD3,Q96DB5,Q99805,Q70UQ0,Q96DE5,P14406,Q9H1E5,P84157,O75964,Q9NUQ9,Q6ZT21,O95070,P82933,Q9NRY5,Q96SK2,Q9NPR9,Q5TC12,Q8NFH4,Q8WUA4,Q5VW38,Q9NUD5,Q3SXM5,A4D1U4,Q8IXU6,Q9Y5M8,Q9Y6X3,Q8NBN7,Q8WUJ1,Q8N6R0,Q15005,Q8IX18,Q15629,O75935,Q9HD45,Q66K14,Q8WVC6,Q9H4I3,Q5SR56,Q9BSC4,Q9Y3B3,Q9HC38,Q9Y320 50 +Tclin 0.4992707054896715 1.9048496138919504 0.0567996224750801 0.2085638859849022 0.1135992449501603 74 O43676,P62942,O43924,Q06203,P03886,P21964,P28074,Q9P0J0,P68371,P38435,P07437,Q9BVA1,Q9BUF5,O96000,Q99720,Q9Y6M9,Q02750,P49721,O75306,P48735 20 +Tchem 0.2715726300247869 0.4558999751664401 0.6484619073895757 0.984728223206796 0.8646158765194342 281 Q03164,O60725,P07099,P42785,Q9UIQ6,Q7L7X3,O43865,P23786,P45880,P30536,P30519,O15269,P55786,O60502,Q9H7Z7,Q13432,Q96K76,Q9NZ08,P04792,P49356,P53985,Q13555,Q16850,Q06124,O75874,P42858,Q5BJF2,Q15418,Q9Y263,O14936,P43490,P48449,Q9H7B4,P51812,P13674,P53396,Q07820,O95470,P09601,Q5JRX3,Q13126,Q15120,P31751,Q14534,Q53EL6 45 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..cf1ac1dcf9b622d42e6f0f357cb4822bc5ccd40f --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2orf49", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CENPF", "CENPI", "CEP170", "CEP44", "CEP55", "CEPT1", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP2L", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG4", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FAU", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOLIM4", "GOLM1", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1147", "KIAA2013", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM12", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANBA", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMADHC", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RIPK1", "RMDN1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STMN1", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMPO", "TMPO", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOR1AIP2", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL5", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WFS1", "WIZ", "WNK1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ACLY", "AHCYL1", "AKT2", "ANAPC16", "ATP13A1", "ATP5L", "ATPAF1", "CAMK2G", "CASK", "COMT", "COX7A2", "CPT2", "CYB5D2", "CYP51A1", "DCAKD", "DCTN3", "DHX40", "EPHX1", "ERAP1", "FAM114A2", "FAM49B", "FKBP1A", "FNTB", "GGCX", "GLOD4", "GPR107", "GPR108", "GTF3C2", "HMOX1", "HMOX2", "HNRNPUL2", "HSDL1", "HSPB1", "HTT", "ICMT", "IDH1", "IDH2", "IKBIP", "KIAA1147", "KMT2A", "LNPEP", "LSS", "MAP2K1", "MAU2", "MCL1", "METTL13", "MFSD14B", "MFSD3", "MGEA5", "MRPS9", "MTAP", "MXRA7", "NAMPT", "ND1", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NOL10", "NPEPPS", "NT5C3B", "NUP37", "P4HA1", "PDCD4", "PDE6D", "PDK3", "PITRM1", "PLAA", "PPAT", "PRCP", "PSMB2", "PSMB5", "PTGES2", "PTPN11", "RABGGTA", "RBMXL1", "RDH13", "RMDN1", "RPS6KA1", "RPS6KA3", "SGPL1", "SIGMAR1", "SLC16A1", "SLC35F2", "SMYD3", "SPCS2", "SPTLC1", "SQLE", "SRPRB", "TAOK1", "TBC1D9B", "TIMM17B", "TM9SF2", "TM9SF3", "TMED7", "TMEM205", "TMEM209", "TMEM97", "TMPPE", "TMX2", "TMX4", "TOMM5", "TRABD", "TRAM1", "TSPO", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UNC119", "USP47", "VDAC2", "YIF1A", "ZCCHC3"]} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/idx2term.json b/protein_atlas_biological_process/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..70295c4f8b4238b6b4daf12bc0160ae8b1e3145c --- /dev/null +++ b/protein_atlas_biological_process/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Apoptosis"} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/plot_0.png b/protein_atlas_biological_process/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7aabbd0c7176299a34eca8d6262c7884d855790a --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2315878f6e89fb93b4e0f838b546d9acfedbd9e0ae1743ef5da434473a1538e4 +size 224779 diff --git a/protein_atlas_biological_process/advanced/plot_1.png b/protein_atlas_biological_process/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7f7c1de06da6f1e9b0d4567a15bad1267fc07db5 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47ec0d29cb3278de8752b92081d26f1f11001394c65318d2bd99fa46df32dba0 +size 210539 diff --git a/protein_atlas_biological_process/basic/idx2term.json b/protein_atlas_biological_process/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7f511fb1c5a73aa751f417d4923ba155d2714580 --- /dev/null +++ b/protein_atlas_biological_process/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Apoptosis", "2": "Phospholipid metabolism", "3": "Adaptive immunity", "4": "Respiratory chain", "5": "Translocation", "6": "Protein transport", "7": "Electron transport", "8": "Phospholipid biosynthesis", "9": "Ion transport", "10": "Hydrogen ion transport", "11": "Lipid metabolism", "12": "Neurogenesis", "13": "Lipid transport", "14": "ER-Golgi transport", "15": "Steroid biosynthesis", "16": "Immunity", "17": "Host-virus interaction", "18": "Differentiation"} \ No newline at end of file diff --git a/protein_atlas_biological_process/basic/plot_0.png b/protein_atlas_biological_process/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..49e06282ef0ddbf15943d7ff75428e7c3c017135 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0662491be171668793cdc3ea9c8e90390c4e11eb5ef43bb5850982733e49ccb8 +size 136921 diff --git a/protein_atlas_biological_process/basic/plot_1.png b/protein_atlas_biological_process/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8f80de5d361be31b7e71798790fb5d6b5d26bc43 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6bb21e6a915906b3beb2824279c7addc26383f085212242428855e3f1d3c3205 +size 137667 diff --git a/protein_atlas_biological_process/basic/plot_10.png b/protein_atlas_biological_process/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..5120605f8ece5b54247b4f703173c4bc51272ec7 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:51db65565b396a3faefc6f8c8d0eef0fe917d60f4fba3840d95dbc5efbb8de7c +size 135587 diff --git a/protein_atlas_biological_process/basic/plot_11.png b/protein_atlas_biological_process/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..a59aa82a8667160240ec90e0c030585ebc515a9c --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:585fe64e82da41bf625014a91618215ad76fbacff296071f7cd1c244654cd9b9 +size 133233 diff --git a/protein_atlas_biological_process/basic/plot_12.png b/protein_atlas_biological_process/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..7e511a87951fe2949caffa266fcc9e83967b5ec9 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:602095146c3d2865ef5b4ba274fec05841e800c6ce46e5c3aa454cf1af4cd833 +size 135322 diff --git a/protein_atlas_biological_process/basic/plot_13.png b/protein_atlas_biological_process/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..99932b2545532c45a61f754f3fbf59ca4fbe6bdd --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d4ebd650bf023da1137f0bfb93cf277b2fbe5faeb8cc64ed92448f3bbc6090f +size 132815 diff --git a/protein_atlas_biological_process/basic/plot_14.png b/protein_atlas_biological_process/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..9b2b11caf9e3c674f13c8759d6668f2f5d1860b9 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a721e90b4e7641778383e325171f10a4d34e07bae630fa4da39aa211cc6bbad +size 144776 diff --git a/protein_atlas_biological_process/basic/plot_15.png b/protein_atlas_biological_process/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..17af0e06bcad8dff399a0f29f0caf09ca232ec4a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:10ca94aacac50784acfe3e6a35d2c0aa009dfc3a610ea24486a710a49a28d71c +size 139556 diff --git a/protein_atlas_biological_process/basic/plot_16.png b/protein_atlas_biological_process/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..d5368152aadfe9549eea0c13d794a3d936d2a576 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:832b4f2a14b12ba7b89683ffb270a595c001bfe5c0ae8fe310cae6d924d2dd15 +size 140354 diff --git a/protein_atlas_biological_process/basic/plot_17.png b/protein_atlas_biological_process/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..9498ccd5d8713bbf186b4463726b3f211ea3f741 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f9f1f76f65d1e69e6a94403674ef356a363b86d47fcb7840a29febb4d5c7ecf2 +size 141730 diff --git a/protein_atlas_biological_process/basic/plot_18.png b/protein_atlas_biological_process/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..71a70d487e1fc161e26a8112aa3d2137ac80bcbd --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41ad8461293c78f5cc674a186ed69afaf2547d11943b7b03825228950eff678e +size 146397 diff --git a/protein_atlas_biological_process/basic/plot_2.png b/protein_atlas_biological_process/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a0786f00ace61cf53f74ae5d30c0fc500b410e39 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0554c3195f5662c5266fc10fc07454621d758d9f22ccbd5f351dbdec5cc4d60b +size 134753 diff --git a/protein_atlas_biological_process/basic/plot_3.png b/protein_atlas_biological_process/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..7de96bc70fcf8d4ef888f2b04879b8578f37799d --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:16323a2764777cdb725d1d0ac25552134454eace95347ae581cdaab8441cead4 +size 127979 diff --git a/protein_atlas_biological_process/basic/plot_4.png b/protein_atlas_biological_process/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ee00f682f28343931ed174688e0b982739919358 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6325359dcfa9a6ec95b95f639e0da9fdd68209cd1e404f8098429ff8d2c176e +size 131273 diff --git a/protein_atlas_biological_process/basic/plot_5.png b/protein_atlas_biological_process/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..a7d57bc268ca1581f07a493dac4e79b825299df1 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1be23218378203f0b4cb05cba01d291751602196b459c411df24bf6d95c458f2 +size 130812 diff --git a/protein_atlas_biological_process/basic/plot_6.png b/protein_atlas_biological_process/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..2cbcee338083bb6ba8acea6d010a82368d996483 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a34667410a807e2781b6db86e33e35ccc73ea237cdce3f12fc9209e8a6bb00f3 +size 134642 diff --git a/protein_atlas_biological_process/basic/plot_7.png b/protein_atlas_biological_process/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..c0eeab1c28b4832e9949d35758bc7b61e6728a28 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9de358fe83abc2d4d653414e0690d90af4bb5e14c5756e2e055ea90cb6ffc915 +size 132597 diff --git a/protein_atlas_biological_process/basic/plot_8.png b/protein_atlas_biological_process/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..31b6cf645383d4d06d72521f8281ed03cec40d03 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e17ec1fd45eb9230dd2d1b4b6f88e14f9ff8268dccd9cd30ac0b4651ff4f226e +size 136747 diff --git a/protein_atlas_biological_process/basic/plot_9.png b/protein_atlas_biological_process/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..ef714f9cfaa21c50cb96f0d6f8132fbbd3af494a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00de93257ed2a0dc5152239dfff4400b5c14b3258e3183bad1d17b1ca6a0ccf8 +size 130754 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..159deae1adc84f53991f9bde9401708598583b0c --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:28f49c8147443347aaeacb1356c29a95f4a3907e79e7587e04f0e1b1d7b9776f +size 77858 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dab75f1d3e2123606cfee2a0a00cfdc858a12784 --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 98 445 4.634357984393365 3.5804693292451617e-06 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 8.939001772517145e-11 1.3452179311911677e-07 3.3474503817062715e-10 5.269629646561488e-09 8.343512076787582e-12 +Apoptosis 38 110 2.4970785740974835 0.0125221206776704 26.983009708737864 120.21844660194176 0.6636399997719048 0.5877814963058052 7.904294191754799 11.993762517847651 0.9312427807662368 0.388650277956022 0.1112157122712446 0.5169656199025946 0.2669973594045687 0.169004833616953 0.0319905892359216 +Symport 1 5 2.276314228100484 0.0228272091378067 2.844660194174758 6.961165048543689 0.6469017708869542 0.3932450371351912 1.8940749800794765 1.272733699501336 1.0491712043829624 0.3136298512602674 1.0 1.0 1.0 0.5632177822757789 0.4967295098899271 +Amino-acid transport 2 8 2.001150056172565 0.0453762213457038 3.063106796116505 7.016990291262136 0.9299828460487652 0.271909550896337 1.9171930478617292 1.3907470472448622 1.1684874391815692 0.271335812648974 0.0559891440928278 1.0 0.2423974925429197 0.1532325517723639 0.1645088237572309 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7ba364287f64eb94202e5526d1ac158e28ab40c2 --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 166, + "title": "Average number of proteins per term", + "value": 28.1144578313253 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7019e30ce32138346065f90502500bc96cf3c1e2 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..291cecbdbc0c923eaa0c40e65ee313a77720f09a --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,49 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.462713503567562 4.634357984393365 3.5804693292451617e-06 0.0005941823763922 0.0005943579086548 445 Q99595,Q9NS69,O60830,Q70HW3,O43676,O43169,A6NIH7,P21796,Q9HD20,Q9BQE5,P03886,Q8N4H5,P23786,O95197,P45880,Q9H2D1,Q9H1E5,Q9Y487,O75964,Q9Y282,Q13432,O00461,Q9P2W9,P30825,Q9BPX6,Q9UBX3,Q13505,Q96L92,Q9UDW1,Q8TB61,Q15629,Q8NHS3,Q99720,Q9Y6M9,P46379,Q9BTX1,O14949,O43772,Q5SR56,Q96CU9,Q9Y6C9,Q6DKK2,Q6P4A7,Q9Y277,Q9Y619,Q9BZF3,O43823,P53992,Q93050,Q96RQ1,Q8NFH4,Q15388,P47985,P16615,Q8IXU6,O14925,O96000,O15027,Q00325,Q3ZCQ8,P55735,Q9Y3B3,P31751,Q92945,Q14728,Q9NZJ7,Q96ES6,Q8NEW0,Q9BUN8,P00403,O95070,Q9BW83,P24539,Q9Y5X3,Q9H3N1,P53985,Q13190,Q8NE01,Q9HC21,Q9UGP8,Q4KMQ2,Q12907,Q8N1F7,Q9UJS0,P51809,Q15363,O75306,Q9Y4C2,O76054,Q9Y2T2,Q01650,P12235,Q96ST2,O15118,P56134,P22626,P20020,O43396 98 +Glyoxylate bypass 0.8843416370106835 2.5142502793184582 0.0119285747180164 0.8635842832251175 0.1385781354995529 2 P48735 1 +Apoptosis 0.436828058091985 2.4970785740974835 0.0125221206776704 0.8765348565355464 0.1385781354995529 110 Q03164,Q14728,Q07021,Q9NZJ7,P61289,P21796,O14681,Q7L7X3,O95197,Q15041,Q96KA5,Q9H3K2,Q9BXK5,P31483,Q9P0J0,O95831,O60313,O60216,Q9NR28,Q9UHX1,Q96A26,Q01085,P42858,P05771,O14737,Q9NXR7,P12236,O96017,P46379,Q6FI81,Q07820,O95470,P09601,O95140,Q96J02,P31751,Q9H8M7,Q53EL6 38 +Symport 0.8310209870278391 2.2763142281004836 0.0228272091378067 0.9783605261372964 0.1531075992051732 5 Q00325 1 +Glycogen biosynthesis 0.7832131153371594 2.0706221731666634 0.0383941183869476 0.9984950556975538 0.2055943113623646 4 P31751,P46976 2 +Amino-acid transport 0.7703925886776543 2.001150056172565 0.0453762213457038 0.9995510963219276 0.2202686995329715 8 P30825,Q6P4A7 2 +Viral RNA replication 0.720284697508899 1.8010166770653968 0.0717002514231728 0.9999956724046106 0.3051856855447868 2 Q15365 1 +Calcium transport 0.7041108902925597 1.7017337824981351 0.0888052845295033 0.999999802549639 0.3595531032170134 6 Q9BPX6,P16615,P20020 3 +Phospholipid metabolism 0.6998958478936499 1.6690872116229925 0.0951000973368929 0.9999999375273556 0.3666828637151351 12 Q96N66,Q9NPH0,Q8NF37,Q9Y6K0,Q99943 5 +Adaptive immunity 0.6851777315209273 1.5978230580711614 0.1100823614852686 0.9999999960909678 0.3710347590144119 13 P04083,Q6P179,Q07021,P04439,Q9NZ08,P01889,Q96FW1,P10321 8 +Respiratory chain 0.6693956054187237 1.5814914801234805 0.1137657054722252 0.9999999980363702 0.3710347590144119 28 P00403,P47985,O14949,O43676,O96000,P03886,Q9UDW1,Q96CU9,Q6DKK2,Q9Y6M9 10 +Purine salvage 0.670557668600908 1.5520093340614245 0.1206599902203375 0.9999999994629256 0.3710347590144119 5 Q13126 1 +GPI-anchor biosynthesis 0.6611203054521458 1.5151368493364803 0.1297377515055859 0.9999999999040768 0.373778986886657 4 Q92643,O43292 2 +Unfolded protein response 0.665844858706081 1.511749985085694 0.1305974773459404 0.9999999999185916 0.373778986886657 9 Q13217,Q9BUN8,Q96CS3,Q15629 4 +Translocation 0.6040972686385865 1.4645072590726105 0.1430554011307043 0.9999999999925844 0.3775748272523759 45 Q99595,Q9NS69,O60830,Q9BTX1,O14925,Q3ZCQ8,Q8NFH4,Q15629 8 +Protein transport 0.3343458801419404 1.4449318079068685 0.1484770408339044 0.9999999999974142 0.3791875196681252 220 Q99595,Q9NS69,O60830,A6NIH7,Q9HD20,Q8N4H5,Q9BUN8,O43823,P53992,O95070,Q9BW83,Q13432,Q8NFH4,Q9P2W9,Q9Y5X3,Q15388,Q13505,O14925,Q9UGP8,Q96L92,Q12907,Q15629,Q8N1F7,P51809,Q9BTX1,O15027,Q3ZCQ8,P55735,Q9Y3B3 29 +Electron transport 0.6097270992820845 1.4181645038812 0.1561427425347066 0.9999999999994236 0.3868611232949447 41 P00403,P47985,O14949,O43676,O75306,O43169,O96000,P03886,Q9UDW1,Q9Y6M9,Q96CU9,Q6DKK2,Q9H3N1,Q9H1E5,O43396 15 +Phospholipid biosynthesis 0.6374381824740527 1.3693329391005575 0.1708952261293057 0.9999999999999692 0.4047349314713234 11 Q96N66,Q8NF37,P35790,Q9Y6K0,Q99943 5 +Ion transport 0.5788005587439322 1.3487636143211543 0.1774129052353292 0.9999999999999916 0.4047349314713234 47 P21796,Q8NEW0,Q6P4Q7,P36542,P05023,P45880,P56134,P20020,Q9Y487,O75964,Q93050,P24539,P06576,P56385,P61421,Q9BPX6,P16615,Q8NE01,Q4KMQ2,Q9UM00,Q9Y277 21 +Sphingolipid metabolism 0.6314259887230944 1.3469825793663683 0.1779858433578711 0.9999999999999926 0.4047349314713234 9 O95470,Q06136,O15269 3 +Vision 0.612272902831456 1.26468636742366 0.2059837787680687 1.0 0.4559107636733254 7 Q13432,O60313 2 +Sensory transduction 0.612272902831456 1.26468636742366 0.2059837787680687 1.0 0.4559107636733254 7 Q13432,O60313 2 +Hydrogen ion transport 0.6009197130232524 1.1792292406035727 0.2383069055616165 1.0 0.4944868290403542 19 O75964,Q93050,P56385,P24539,P06576,P36542,P56134,Q9Y487 8 +Transcription termination 0.5768683274021318 1.1384058395443202 0.2549510567887076 1.0 0.5134380793753934 2 Q08211 1 +ATP synthesis 0.581865679373726 1.1195512477912302 0.2629050406440267 1.0 0.5134380793753934 7 O75964,P36542,P56134,P06576 4 +Lipid metabolism 0.3240893504295322 0.987277039221812 0.323506843582527 1.0 0.5901333630186756 106 Q9P035,Q9Y217,Q9NPH0,Q06136,O15118,P23786,Q709F0,Q15392,O15269,Q8N2A8,Q8NF37,Q9H7Z7,Q9NZ01,Q16850,P51648,Q96N66,O15254,P48449,Q9BY49,Q15067,O00116,P53396,O95470,Q15800,P35790,Q9Y6K0,P37268,Q96G23,Q99943 29 +Neurogenesis 0.5340841172969598 0.957085684577298 0.3385240085198706 1.0 0.5915261622557739 41 Q13555,Q9BVA1,Q9NQC3,Q969G3,Q8WUJ1,Q7L576,P55209,Q16637,Q14155 9 +Cholesterol biosynthesis 0.5239975735520455 0.8084855825404325 0.4188111024244401 1.0 0.655146998722777 13 Q15392,Q16850 2 +Sterol biosynthesis 0.5023188017033617 0.6996896167165785 0.4841211623040538 1.0 0.7175367227006512 14 Q15392,Q16850 2 +Spermatogenesis 0.4999934042233728 0.6638752817971536 0.5067701378524432 1.0 0.7444587865796952 22 Q08J23,Q8N2A8,P46379 3 +Lipid transport 0.486345527884395 0.6066716224624473 0.544068858237106 1.0 0.776302164443976 18 Q9BZF3,O15118,Q9BQE5,Q4KMQ2,Q99720,Q9BZF1 6 +Notch signaling pathway 0.4643874643874687 0.6020321599733749 0.5471527303611157 1.0 0.776302164443976 4 Q96T58,Q9NVX2,Q92542 3 +Cilium biogenesis/degradation 0.4778043770501824 0.5744931567164644 0.5656341300724785 1.0 0.7957225897629783 16 A6NIH7 1 +Stress response 0.4790837332416731 0.5615080841210002 0.5744512208507628 1.0 0.7963666145800535 30 Q14011,P04792,Q15418,O95197 4 +Methionine biosynthesis 0.4288256227758018 0.4731154310396652 0.6361308282165676 1.0 0.8459774070773296 2 Q9BV57 1 +Meiosis 0.4553883042946063 0.4718537530678084 0.6370311800281097 1.0 0.8459774070773296 16 Q8N2A8 1 +ER-Golgi transport 0.4283550044206184 0.3906858497453121 0.6960294595130767 1.0 0.8958338761695317 47 Q9Y678,P49755,Q9Y282,Q15363,P53992,O95070,Q96RQ1,O15027,P55735,Q9P2W9,O95197 11 +Steroid biosynthesis 0.4403046974031966 0.3905091908816979 0.6961600603968048 1.0 0.8958338761695317 19 Q16850,Q15800,P48449,P37268,Q15392 5 +Immunity 0.3304127281389019 0.3507451584438963 0.7257795435929033 1.0 0.9267646479724766 75 Q6P179,P04083,Q07021,Q15233,P01889,P10321,O43823,Q96PK6,O75179,Q9NZ08,Q9NUD5,Q8N5M9,Q8IXJ6,P04439,Q9Y3Z3,P17931,P46379,Q9UQ84,Q96J02,Q96FW1 20 +Cholesterol metabolism 0.4267927993938816 0.3234785802286674 0.746332826803263 1.0 0.9342873929012802 21 Q16850,Q15392 2 +Sterol metabolism 0.4118514960327413 0.2569618860304632 0.7972081958731212 1.0 0.9659602957294752 22 Q16850,Q15392 2 +Steroid metabolism 0.4027553198232817 0.2163765080000118 0.8286942764388023 1.0 0.9845078858299332 23 Q16850,Q15392 2 +Host-virus interaction 0.2648034755469813 0.1782465461100531 0.8585293564654477 1.0 0.9971779031182636 230 P12235,Q01105,P61289,P21796,O60506,O15118,O95197,Q9BUN8,P08670,P01889,P22626,O43765,P10321,Q9ULX6,Q8IZA0,P61978,P28074,O60502,O75525,Q9P0J0,O75179,P28072,P04792,P13051,P04439,Q9Y3Z3,Q96JB5,O43760,P35613,Q15629,Q99436,P49721,Q9GZP9,Q15369,Q96PU5,Q96J02,Q86X55,Q9Y679,Q9Y2T2 39 +Antiport 0.3425963409785134 0.1302362940217049 0.8963794806239225 1.0 1.0 6 P12235,O95202,P12236 3 +Purine biosynthesis 0.3461201475563078 0.1154481287783748 0.908089932707923 1.0 1.0 9 Q06203 1 +DNA synthesis 0.290850836596659 0.0380902716840652 0.969615707754352 1.0 1.0 3 P49454,P35232 2 +Glucose metabolism 0.3098671735723584 0.0208725012616946 0.9833473626583644 1.0 1.0 10 Q15120 1 +Differentiation 0.2873082221334156 0.0181420420843795 0.98552553872927 1.0 1.0 76 Q13555,Q8N2A8,O96005,Q07820,Q08J23,Q9BW83,Q7L576,P51114,Q99829,P46379 10 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5a5f2cf2c11e4a7ed5e8aa1e979c77d21a377f3b --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Biological rhythms", "Biomineralization", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cytoplasmic inwards viral transport", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "Digestion", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Methionine biosynthesis", "Methotrexate resistance", "Microtubular inwards viral transport", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF3", "ABHD12", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP8", "AKAP8L", "AKT2", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEX1", "API5", "APOBEC3C", "APOL2", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL8A", "ARMT1", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "AUP1", "BABAM2", "BAG6", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BICD2", "BIRC6", "BMS1", "BNIP1", "BOP1", "BPTF", "BRD1", "BRD2", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "CACNA2D1", "CACYBP", "CAD", "CAMK2G", "CAND1", "CANX", "CAPRIN1", "CARM1", "CARS", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CENPF", "CEP55", "CEPT1", "CERS2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "COG2", "COG7", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS6", "COPS7B", "COPZ1", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CRNKL1", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DCAF1", "DCAF13", "DCAF7", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX35", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPYSL2", "DR1", "DSG2", "DTYMK", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECH1", "ECHS1", "ECI1", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESS2", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXRED1", "FRG1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCC2", "GCFC2", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GHITM", "GINS2", "GINS3", "GINS4", "GLRX", "GM2A", "GMPS", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLIM4", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GRB2", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSS", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPB11", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INCENP", "INTS13", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITPA", "IVD", "IWS1", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0319L", "KIF11", "KIF18A", "KIF1B", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LAMP1", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPGAT1", "LRP1", "LRPPRC", "LRRC41", "LRSAM1", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAD2L1", "MAGT1", "MANF", "MAP2K4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDC1", "MDH1", "MDH2", "MECP2", "MED24", "MED4", "MFAP1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGME1", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MKRN2", "MLEC", "MMS19", "MOB4", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MRE11", "MRPL41", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MTX3", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAMPT", "NAP1L1", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NHP2", "NIP7", "NIPBL", "NKRF", "NLE1", "NME1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NPC1", "NPC2", "NPLOC4", "NPM1", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NUDC", "NUDCD1", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PANK4", "PAPOLA", "PARK7", "PARN", "PARP1", "PAWR", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK3", "PDS5A", "PDS5B", "PECR", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF5A", "PHF6", "PHGDH", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIR", "PITHD1", "PITPNB", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PNN", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POP7", "PPAT", "PPID", "PPIF", "PPIH", "PPIL1", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1R8", "PPP2R1A", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA1", "PRKAG1", "PRKCB", "PRKDC", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRSS3", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RAPGEF2", "RARS", "RBBP5", "RBBP6", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCOR1", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RIF1", "RIPK1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDHA", "SDHB", "SEC13", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT2", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMU1", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SON", "SORT1", "SPAG5", "SPC24", "SPC25", "SPECC1L", "SPEN", "SPTLC1", "SPTLC2", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STAT1", "STAT3", "STAU1", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "TACC3", "TAF2", "TAF5", "TAF6L", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBCB", "TBK1", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TECR", "TERF2IP", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TK1", "TLN1", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM14C", "TMEM214", "TMX1", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TP53BP2", "TPI1", "TPR", "TPRKB", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TSR3", "TTC19", "TTC26", "TTC4", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBL5", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "VAMP7", "VAPA", "VAPB", "VARS1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VTA1", "WAPL", "WARS", "WARS2", "WBP11", "WDR12", "WDR33", "WDR36", "WDR43", "WDR5", "WDR6", "WDR61", "WDR75", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "ZBTB10", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCRB1", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ACAD11", "ACLY", "ACOX1", "ACOX3", "ACP6", "ADI1", "AGPAT1", "AGPS", "AIFM1", "AKAP8", "AKAP8L", "AKT2", "ALDH3A2", "ANKRD17", "ANO6", "ANXA1", "AP3M1", "APOL2", "ARHGEF7", "ARL6IP1", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5I", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "AUP1", "BABAM2", "BAG6", "BCL2L13", "BSG", "C1QBP", "CAMK2G", "CARM1", "CDK5RAP3", "CENPF", "CEPT1", "CERS2", "CHEK2", "CHKA", "CIAPIN1", "CIRBP", "CLPTM1", "CLPTM1L", "CNNM3", "CNNM4", "COPG1", "COX2", "CPNE1", "CPT2", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DERL1", "DERL2", "DHCR24", "DHX9", "DIABLO", "DNAJC3", "EI24", "ELOC", "ERAP1", "ERAP2", "ERGIC2", "ERGIC3", "EXO1", "FAF2", "FAM162A", "FDFT1", "FOXRED1", "FXR1", "GHITM", "GOLIM4", "GPAA1", "GYG1", "HACD3", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HNRNPA2B1", "HNRNPK", "HSPB1", "HTT", "IDH2", "IFT27", "ITCH", "IWS1", "JAGN1", "KDSR", "KHDRBS3", "KHSRP", "KIAA0319L", "KMT2A", "LETM1", "LGALS3", "LMAN2", "LPCAT1", "LSS", "MBOAT7", "MCL1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MGEA5", "MICU1", "MINDY3", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTMR6", "MTX1", "NAP1L1", "NCSTN", "ND1", "NDC1", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NEDD4L", "NLE1", "NONO", "NPC1", "NSUN2", "NUP37", "NUP93", "OPA1", "OSBPL6", "OSBPL8", "OTUB1", "PCBP1", "PDCD4", "PDCD5", "PDK3", "PECR", "PHB", "PIGK", "PLD6", "PPAT", "PRKCB", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PSME3", "PTGES2", "PUF60", "RAD21", "RBM14", "RPS6KA1", "RTN3", "RTN4", "SAMHD1", "SEC13", "SEC14L2", "SEC16A", "SEC24C", "SEC63", "SET", "SFXN4", "SGPL1", "SGTA", "SIGMAR1", "SIRT2", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A6", "SLC30A7", "SLC35B2", "SLC35F2", "SLC7A1", "SLC7A5", "SMARCE1", "SMN1*", "SNX27", "SNX5", "SPEN", "SPTLC1", "STX18", "STX5", "SYNCRIP", "SYNGR2", "TAOK1", "TCAF1", "TECR", "TIA1", "TIAL1", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TMCO1", "TMED10", "TMED2", "TMED7", "TMX1", "TMX4", "TOMM20", "TOMM22", "TOMM5", "TRAM1", "TTC19", "TUBB2B", "TXNL1", "UNC119", "UNC119B", "UNG", "UQCR10", "UQCRFS1", "UQCRQ", "VAMP7", "VDAC1", "VDAC2", "VDAC3", "VIM", "YIF1A", "ZCCHC3"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e26eb379e10df789e521b26c68f7cfbfe5f61ad6 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease", "1": "FDA approved drug targets"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/plot_0.png b/protein_atlas_disease_involvement/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..94143002ede83fa53ab08e873a9321b7db9350a4 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3cf4ee1e2f28fa874a404fe9b24bb908c3cd3e1abc0c8382823597c31fc41312 +size 210407 diff --git a/protein_atlas_disease_involvement/advanced/plot_1.png b/protein_atlas_disease_involvement/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..bc3e1310ff034a90aa440cf0ad14d4984b6c3ad1 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7eb725e766c7467d0811bfdc6536d81f0f3f409ae63d319a0bd506dd2c902041 +size 210026 diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cf5cdc7eefbe0bc312c16dbbc0ca9b9b36af33e2 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease", "1": "FDA approved drug targets", "2": "Deafness", "3": "Diabetes mellitus", "4": "Charcot-Marie-Tooth disease", "5": "Amyotrophic lateral sclerosis", "6": "Neurodegeneration", "7": "Neuropathy", "8": "Proto-oncogene", "9": "Cancer-related genes"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..1c318771a0751e883689d6e4491287140dda60a1 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bfa8653c4909d519f12b51413e9ce3dedad5a8924df46c879434703374a0a599 +size 141524 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4789ef8aaf71890376d83dde2a74fa9782686a84 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5f2b171e9f603f43a5988e98ebe09c6148dc8cce71ddcc2230b80e0fbb3242a +size 145558 diff --git a/protein_atlas_disease_involvement/basic/plot_2.png b/protein_atlas_disease_involvement/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..905fb62f5f806cfc45b9025c62968728f82357c0 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6479d9b387d5cea4e236ec0a01a084157e9a740aa0c30e03241914f7a484a78 +size 129293 diff --git a/protein_atlas_disease_involvement/basic/plot_3.png b/protein_atlas_disease_involvement/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..e8a207dd2eb16a62fa078070b30858324c463e76 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca01e9366ec36c5043615c8579a58f060cea181679f252cb1168214849043e00 +size 134906 diff --git a/protein_atlas_disease_involvement/basic/plot_4.png b/protein_atlas_disease_involvement/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..649ec1bc40b4813d8aaa14eb1ede225e8a7da16d --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63a2744429360500e0a6e383c4270e7f0de73f6ad58479b489ea283b3bcab1dd +size 151095 diff --git a/protein_atlas_disease_involvement/basic/plot_5.png b/protein_atlas_disease_involvement/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..f07cd818b2feb88b9eee2b2fc1bb8e0a7cdc6b63 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2c6e77305ce320820b7410e900056987d2c609f3a092c970d39ada53f7e6c18c +size 147929 diff --git a/protein_atlas_disease_involvement/basic/plot_6.png b/protein_atlas_disease_involvement/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..7a3b4f6c34a635092dedaee19371f22d3db2039d --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d67eafb5059dadc5ead8f377c2b63df4b36df0959a22754dd9ac3d521fc0cde1 +size 143795 diff --git a/protein_atlas_disease_involvement/basic/plot_7.png b/protein_atlas_disease_involvement/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fc8ce58afa520d7e43ca7c0fcf5c50e25ce88558 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:247fb001f62ef64ba168c083e6ae7a950e4c2e062c6e8896daf024a98eecc40b +size 142511 diff --git a/protein_atlas_disease_involvement/basic/plot_8.png b/protein_atlas_disease_involvement/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..d1ebed786acdd2de2095e0a4287f66f32902f92b --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47f377fe24ca95ae20ad7a594d0d6030786b47767f37e6191735f809c6be11cc +size 144757 diff --git a/protein_atlas_disease_involvement/basic/plot_9.png b/protein_atlas_disease_involvement/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..eaa62bccc20c251a8d90f42d36e8795ca450d3d7 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:507e1f663ed8fe8a4ad2574b49b4fceaf1d04d9ce343d65dc56208c46f668f00 +size 142654 diff --git a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..2cb562d14ab9a5628e9018e5c7f707a348fc7839 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3f3ac414256bbd7176b7cd23d4fd76e755748580c4c3692029c8feb7ecc741d0 +size 74936 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0852a1c529f369bfac766285a5ea6b1774d62bb4 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 22 77 2.722806141169676 0.0064730028898372 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 1.2694032450483084e-05 0.0077142504779524 0.0010405769745358 1.137527056377041e-05 1.6129529088515749e-06 +FDA approved drug targets 27 109 2.488573095156127 0.0128256869235048 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 0.0006550905750623 0.1692658520693615 0.0005769894192108 0.0009822569935543 0.0003413792750152 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b2c97fc0961a9c55cc8cf4ceec37a322e1100d93 --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 112, + "title": "Average number of proteins per term", + "value": 19.982142857142858 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..960e327fc1c06ba974d4b944816203b7fc6a8e31 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..829de82cce707906df2f2c88d6d9012ac0e931d2 --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,31 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.562416520191711 2.722806141169676 0.0064730028898372 0.5168039878708184 0.1021131913967981 77 O75880,P13073,Q70HW3,O43676,O43819,P03886,Q5JTZ9,P00403,Q5JPH6,Q9Y2R0,O95831,O60313,Q9UBX3,Q7KZN9,P47985,Q9Y6M9,Q9BQP7,O14949,O75306,Q96CU9,Q6DKK2,Q6P4A7 22 +FDA approved drug targets 0.4368658293942019 2.488573095156127 0.0128256869235048 0.7644349937685374 0.1198927258027458 109 P12235,P04083,P62942,P36404,P49327,P03886,P21964,P23786,P20020,P28074,P31939,P68371,Q13423,P38435,P49356,P07437,Q16850,P16615,P15260,O75874,Q16637,Q99720,P49721,Q02750,P53396,P48735,Q14534 27 +Rhizomelic chondrodysplasia punctata 0.8530249110320394 2.382494530275915 0.0171957874372512 0.8566805795684556 0.1198927258027458 2 O00116 1 +Progressive external ophthalmoplegia 0.8035112422289232 2.1647681766417444 0.0304054430353972 0.9685153472429644 0.1362163847985797 3 Q9BQP7 1 +Meckel syndrome 0.7790035587188764 2.0627678943041707 0.0391346857614789 0.9885659042178824 0.1685801848186785 2 Q7Z4L5 1 +Hirschsprung disease 0.7594306049822045 1.9762925507210225 0.0481216528194776 0.9960086284500788 0.179283066834047 2 P42892 1 +Joubert syndrome 0.7310966191509435 1.8369594005603869 0.06621588912772 0.99953483638802 0.1901584508283242 4 Q7Z4L5 1 +Dystroglycanopathy 0.6985765124555158 1.7025522210226138 0.0886518979209527 0.9999694760404384 0.2421710382230904 2 O43505 1 +Xeroderma pigmentosum 0.6614453542185836 1.524239280403855 0.1274489489284156 0.9999997663451756 0.30370813361665 3 P18074,Q92889 2 +Cockayne syndrome 0.6614453542185836 1.524239280403855 0.1274489489284156 0.9999997663451756 0.30370813361665 3 P18074,Q92889 2 +Amyloidosis 0.6222232433300083 1.3331346992712363 0.182487604054915 0.9999999998417416 0.3753225002895276 4 P03886 1 +Deafness 0.5611017120166792 1.2340773438871773 0.217174084966975 0.9999999999987684 0.4193706468327792 47 Q9NR28,Q15067,Q06124,Q13217,Q9Y287,Q16740,O76024,P68371,O95831,O75648,O60313,O60443 12 +Primary microcephaly 0.6016668331874526 1.2086280880482865 0.2268057603839479 0.999999999999692 0.4305465281864774 8 Q86XL3 1 +Diabetes mellitus 0.5953629072900983 1.1686613169189768 0.2425401131213607 0.9999999999999692 0.4527415444932066 10 Q13217,Q9UKG1,P13807,P03886,O76024,Q5VV42,P31751 7 +Osteogenesis imperfecta 0.5888248560635924 1.1527708085377408 0.2490044690668447 0.9999999999999882 0.4571885333686329 7 Q96AY3,Q32P28 2 +Nemaline myopathy 0.5576512455515976 1.048637593715523 0.2943449465485726 1.0 0.4994944547490928 2 Q9Y281 1 +Non-syndromic deafness 0.5317755232982881 0.8317049730622219 0.4055754929199517 1.0 0.6308952112088138 17 Q9NR28,O76024,O60443,O75648 4 +Gaucher disease 0.5049822064056901 0.8051785851108101 0.4207166323371814 1.0 0.6367603084022204 2 P07602 1 +Craniosynostosis 0.4745247216454976 0.6467039160565079 0.5178235881350277 1.0 0.7160029860632482 4 P07237,P16435 2 +Primary ciliary dyskinesia 0.4498220640569349 0.5608237117695845 0.5749177204654852 1.0 0.7575386434368746 2 P49454 1 +Charcot-Marie-Tooth disease 0.4759957934939184 0.5480367359755185 0.5836666786532474 1.0 0.7601240466181826 21 Q8TB36,Q15120,Q9Y6X9,O95831,P04792,P54802 6 +Amyotrophic lateral sclerosis 0.4613321027462005 0.5038956682005822 0.614334694762646 1.0 0.7768318764744462 15 P50995,P35637,Q9NRR5,P43243,Q99720,Q13501 6 +Neurodegeneration 0.287584778261943 0.4996750520607116 0.6173039018413009 1.0 0.7768318764744462 119 P50995,P03886,Q96BR5,Q15041,P05023,Q5JTZ9,O15269,Q9NXN4,Q69YN2,Q9Y4W6,Q9Y287,P54886,Q9NSD9,O95831,Q96A57,P04792,O60313,Q15813,P42858,Q16637,Q9Y6X9,Q8NHS3,Q99720,Q8NCW5,Q8TD16,P54802,Q13217,Q8TB36,P04080,P35637,Q96B26,Q15120,Q9Y320 33 +Neuropathy 0.4487017906977167 0.4783344945549203 0.632412148718072 1.0 0.7870017850713785 44 O15269,Q15067,Q9HC21,Q13217,Q8TB36,P48643,Q15120,O95831,Q96BR5,Q9Y6X9,P05023,P04792,P54802 13 +Glaucoma 0.4129583481666098 0.3986515540952808 0.6901499691026283 1.0 0.8401825710814605 3 Q9UHD2,Q9UM00 2 +Leigh syndrome 0.409022924318387 0.3432416334378205 0.7314166860827898 1.0 0.8808459015190586 7 O43819 1 +Proto-oncogene 0.4286010133335145 0.3260099441568163 0.7444168314580468 1.0 0.8869647353542686 38 Q03164,Q8WY22,Q01105,Q06136,Q16204,P35637,O96028,P49589,P31751,Q92804 10 +Congenital disorder of glycosylation 0.4051733662413515 0.2676007821592661 0.789006628838195 1.0 0.9043255828134418 15 Q9BT22,Q8N511 2 +Lissencephaly 0.3195840299991434 0.0563446338183015 0.955067262642428 1.0 1.0 8 O43505,Q9Y320 2 +Cancer-related genes 0.2558560278689065 0.0160057873528023 0.9872297746472172 1.0 1.0 341 Q99595,Q03164,P04083,Q07021,P50995,P07099,Q01105,Q06136,Q15233,O96028,O14681,P33176,Q9BQE5,P49327,P46977,P49589,P21266,O95067,P05023,P01889,Q5JTZ9,Q92804,P22626,O95684,Q16204,P31939,Q969G3,Q99543,P52789,P40818,P04792,P11802,P04843,Q06124,O75874,P08236,P04439,Q92733,Q15418,P80303,P43490,Q9H7B4,Q8N1F7,P51812,P27824,P67809,Q02750,Q13451,Q92769,P53396,Q07820,P09960,P04080,P35637,P09601,P38159,P48735,Q8IUD2,Q96PU5,Q86X55,P31751,Q92889 62 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..0623acee1c2be8f5e1db1455dc2390396728a7f8 --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AARS", "AARS2", "ABCB1", "ABCB7", "ABCC1", "ABHD12", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD5", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKR1B1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APPL1", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATP11C", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATXN10", "B3GALT6", "B4GAT1", "BANF1", "BAZ1B", "BCAP31", "BCLAF1", "BCOR", "BCS1L", "BICD2", "BIRC6", "BLMH", "BLVRB", "BMS1", "BPTF", "BRI3BP", "BUB1B", "C19orf70", "C1QBP", "CACNA2D1", "CAD", "CALR", "CAMK2G", "CANX", "CAPN1", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC6", "CCDC8", "CCNB1", "CCNB2", "CCT5", "CDC16", "CDC27", "CDC37", "CDC42", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKAL1", "CENPF", "CEP55", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHEK2", "CHMP2B", "CHMP4B", "CISD2", "CKAP2L", "CKB", "CKMT1A*", "CLIC1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "COA3", "COA7", "COG2", "COG7", "COLGALT1", "COMT", "COPA", "COPB2", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT2", "CRTAP", "CSDE1", "CSE1L", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTCF", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CYB5R3", "CYC1", "CYP51A1", "DAD1", "DARS", "DARS2", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIS3", "DKC1", "DLD", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPM1", "DSG2", "DSP", "DYNC1H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHMT1", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EZR", "FAF1", "FAH", "FAM120A", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FBXO7", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GALK1", "GALM", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GCDH", "GCLM", "GDAP1", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI3", "GNPAT", "GNS", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GRB2", "GSDME", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUSB", "GYG1", "GYS1", "H4C1*", "HADH", "HADHA", "HADHB", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGA2", "HMGB3", "HMGCR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2R", "ILF3", "IMPAD1", "IMPDH2", "INTS1", "IPO7", "IQSEC1", "IRF2BPL", "IRS4", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF1B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KMT2A", "KTN1", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRP1", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MARS", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MDC1", "MDH1", "MDH2", "MECP2", "MFN2", "MFSD8", "MGME1", "MICU1", "MID1", "MIF", "MIPEP", "MKI67", "MMADHC", "MOGS", "MORC2", "MPDU1", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFS", "MTOR", "MTPAP", "MTR", "MUT", "MYH10", "MYH9", "MYO6", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPH", "NCSTN", "ND1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NEDD4L", "NEK9", "NF1", "NHLRC2", "NHP2", "NIPBL", "NME1", "NNT", "NONO", "NOP56", "NPC1", "NPC2", "NPM1", "NSD2", "NSDHL", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OPA1", "OSGEP", "OXCT1", "P3H1", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAPSS2", "PARK7", "PARN", "PARP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE6D", "PDHA1", "PDHB", "PDK3", "PEPD", "PEX14", "PEX19", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POLR3B", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PTPN11", "PTRH2", "PUF60", "PUM1", "PURA", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QPRT", "RAB10", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RBM10", "RBM12", "RBM15", "RBM28", "RBMX", "RBPJ", "RDH11", "RDX", "REPS1", "RFC1", "RFC2", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "ROCK1", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS26", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RTN4IP1", "SAMHD1", "SARS", "SART1", "SBDS", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SIGMAR1", "SIL1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC38A1", "SLC3A2", "SLC9A3R1", "SLC9A6", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOD2", "SON", "SORD", "SPART", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRP54", "SRP72", "SRSF3", "SSB", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TAF15", "TAF2", "TALDO1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBC1D8B", "TBCD", "TBCE", "TBK1", "TBL2", "TCEA1", "TCF20", "TCOF1", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM50", "TK1", "TKT", "TMCO1", "TMEM199", "TMEM230", "TMEM43", "TMTC3", "TMX2", "TNPO3", "TOP1", "TOP2A", "TOP2B", "TOR1AIP1", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPRKB", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TTC21B", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "UBA1", "UBE3A", "UBQLN4", "UBR1", "UBR5", "UBTF", "UFM1", "UGDH", "UGP2", "UMPS", "UNC119", "UNG", "UPF3B", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USP8", "USP9X", "UTP4", "VAPB", "VARS1", "VCL", "VCP", "VIM", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VRK1", "WARS", "WARS2", "WBP2", "WDR1", "WDR11", "WDR36", "WDR5", "WFS1", "WNK1", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "XRN1", "YARS", "YARS2", "YBX1", "YEATS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZMPSTE24"], "leading_proteins": ["AARS2", "ACLY", "ACOX1", "AFG3L2", "AGPS", "AIFM1", "AKT2", "ALDH18A1", "ALG1", "ANKLE2", "ANXA1", "ANXA11", "APOL2", "APPL1", "ARL2", "ARL6IP1", "ATIC", "ATP1A1", "ATP2A2", "ATP2B1", "B4GAT1", "BICD2", "BRI3BP", "C1QBP", "CANX", "CARM1", "CARS", "CCDC6", "CCNB2", "CCT5", "CDK4", "CDKAL1", "CENPF", "CFL2", "CLPP", "COA3", "COA7", "COMT", "COX15", "COX2", "COX4I1", "CPT2", "CSTB", "CWF19L1", "CYP51A1", "DIABLO", "DNAJC2", "DNAJC3", "EARS2", "ECE1", "EI24", "EPHX1", "ERC1", "ERCC2", "ERCC4", "EXOSC8", "FARSB", "FASN", "FGFR1OP", "FKBP10", "FKBP1A", "FKBP5", "FNTB", "FOXRED1", "FUS", "GDAP1", "GDAP2", "GGCX", "GSDME", "GSTM3", "GUSB", "GYS1", "HDAC2", "HK2", "HLA-A", "HLA-B", "HMOX1", "HNRNPA2B1", "HSPB1", "HTT", "IDH1", "IDH2", "IFNGR1", "ITM2B", "KDSR", "KIF5B", "KMT2A", "LTA4H", "MAP2K1", "MATR3", "MCL1", "MFSD8", "MGME1", "MORC2", "NAGLU", "NAMPT", "NAXE", "ND1", "NDUFB3", "NDUFB9", "NDUFS2", "NEDD4L", "NNT", "NONO", "NSD2", "NUCB2", "NUP93", "OPA1", "P3H1", "P4HB", "PDK3", "POR", "PRCC", "PSAP", "PSMB2", "PSMB5", "PTPN11", "RBMX", "RPN1", "RPS6KA1", "RPS6KA3", "SCO1", "SCO2", "SET", "SFXN4", "SIGMAR1", "SLC25A10", "SLC25A19", "SLC25A26", "SLC25A4", "SMARCE1", "SMN1*", "SMYD3", "SPTLC1", "SQLE", "SQSTM1", "STT3A", "TAF15", "TBCE", "TBK1", "TIMM17A", "TMCO1", "TMEM199", "TMEM230", "TMX2", "TRMU", "TTC19", "TTC21B", "TUBB", "TUBB4B", "UBQLN4", "UQCRFS1", "UQCRQ", "USP8", "WFS1", "YBX1"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/protein_atlas_molecular_function/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/idx2term.json b/protein_atlas_molecular_function/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9aa351358d7a5a1ba3699c9230b5149e33daf651 --- /dev/null +++ b/protein_atlas_molecular_function/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Oxidoreductase", "1": "Metalloprotease", "2": "Translocase", "3": "Chaperone", "4": "Transferase", "5": "Receptor", "6": "Protease", "7": "Acyltransferase", "8": "Methyltransferase", "9": "Glycosyltransferase"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/plot_0.png b/protein_atlas_molecular_function/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..4475b781bac05aa187c6766d145f3809810550fc --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8508b2e2b4d98e47489eeaa352196933bdf4ea9e1c7e187a623a13e11f588bd5 +size 138473 diff --git a/protein_atlas_molecular_function/basic/plot_1.png b/protein_atlas_molecular_function/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ff4d86c2b010a3946bfd75bf9c7114f22819d794 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:421ba1b3701b71052832b826ff4505d207adf5553aba4eebd52d89c2eb22cb19 +size 134934 diff --git a/protein_atlas_molecular_function/basic/plot_2.png b/protein_atlas_molecular_function/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ac2f1f26768217ba5f42f1d7e7ab1dc4f95f22c6 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63aaea870dfd4b8c7ddb9a3679390c568997e57dafadbe58e53cd3e01e6392e8 +size 132965 diff --git a/protein_atlas_molecular_function/basic/plot_3.png b/protein_atlas_molecular_function/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..1aa7ea11c8e73e90376cb186a748377a646dd1c4 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a5b500605d97e101693f264170e139046f267698ed500f2ef78afa9189e4ee4d +size 137689 diff --git a/protein_atlas_molecular_function/basic/plot_4.png b/protein_atlas_molecular_function/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..bc46d3018f8ed11c4eec35ab17500cd4f3b49e3c --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ddd57188086dde7de128dc9615091930ae87bf8879b376b944fd1505cbf53319 +size 136659 diff --git a/protein_atlas_molecular_function/basic/plot_5.png b/protein_atlas_molecular_function/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..898bb83a113a7695a8a3fff720b8c39faa376c29 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a19b5a0ccab8626c7969dc3734b99ff973a9b29358d047536c905f8b1b4df95 +size 131712 diff --git a/protein_atlas_molecular_function/basic/plot_6.png b/protein_atlas_molecular_function/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..45ecbc7f04cfd047752409dcab20f7b473296f84 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74e53f3adf49582033b225ee2e41dc3fac40e28e8adb1e6eeb07a0ee6dff37dd +size 134429 diff --git a/protein_atlas_molecular_function/basic/plot_7.png b/protein_atlas_molecular_function/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..0670354d870c7015a09ec465007f7bedea96d9d6 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:087944032253f3a57b61ae6363503a43157356bd08988135075939b5cc0e008a +size 139265 diff --git a/protein_atlas_molecular_function/basic/plot_8.png b/protein_atlas_molecular_function/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..0fe716f25f25493474a4806772fbf068bea875b3 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:358efcb209e182390171096252a9b097cca80c4e91458927cff911a88961012e +size 135627 diff --git a/protein_atlas_molecular_function/basic/plot_9.png b/protein_atlas_molecular_function/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9a06774cdf68e0ea665c3e6b55031488105cfbae --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:439394819b9e9677bb7886208f0b9271b7fd88915efb391428137db4ff73231b +size 150925 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e8ea44c743e3c846082463ef7afa041e0a793a2c --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f56d4131bbd84e323d3d8c3d15db850cfaf2bd412d5800062d460d35380917d +size 73258 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..50034156602cfa21005b36fefc0d94a14797f5fa --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 34.670103092783506 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..615b5e40da161464e329a7f81233bef61efddb01 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7b145779858a8ec7618c208f1d3b69321bc3a5b5 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,25 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Monooxygenase 0.9533807829181516 2.7974471843477633 0.0051508187739304 0.3940274597494138 0.0624536776339063 2 Q16850 1 +Prenyltransferase 0.9262329059183336 2.6845128651103245 0.0072635587775033 0.5069459546421561 0.0704565201417829 3 Q92696 1 +Porin 0.9144362994496416 2.6334647491673215 0.0084518608629715 0.5610258257444859 0.0745300457916583 4 P45880,P21796 2 +Threonine protease 0.8764684941260357 2.4776159651376184 0.0132263420134015 0.7251459746223003 0.0901369853961321 3 P28072,P28074 2 +Phospholipase A2 inhibitor 0.7889679715302649 2.106485085061549 0.0351622373428324 0.9689496561772734 0.1624160486787973 2 P04083 1 +Oxidoreductase 0.3709824184970646 1.9324080733004405 0.0533091583632865 0.995077417010839 0.2068395344495517 152 P13073,Q9BU89,Q06136,Q8N8N7,Q8NB78,P49327,Q709F0,Q9UHG3,P36551,Q15392,Q92947,P30519,P54886,Q9NZ01,O95831,Q6ZRP7,Q16850,P51648,O75874,Q8NBN7,O15254,P30837,P13674,Q9BY49,Q15067,Q8TED1,O43175,O75306,Q15800,P09601,P48735,Q32P28,Q8NBX0,Q96CU9,P16435,Q14534,Q8N4Q0 37 +Aminopeptidase 0.6824545481523376 1.5883331697386434 0.1122110207435822 0.9999903162024006 0.3401396566289837 10 Q9UIQ6,Q9NY33,P55786 3 +Metalloprotease 0.6297761448155488 1.3538806986070842 0.1757744423049589 0.9999999928142936 0.4262530225895255 26 Q9NY33,Q9Y4W6,P55786,P52888,P42892,P09960,Q9UIQ6,Q5JRX3,Q9BYT8,Q9NZ08,O75844 11 +Translocase 0.6288678305684396 1.3238702759212042 0.1855461314946094 0.9999999977403063 0.428523208451836 20 P00403,P47985,P16615,O75306,Q9HD20,P03886,Q13423,P20020 8 +Chaperone 0.3414179563411363 1.2116900941361397 0.2256310324192756 0.9999999999830976 0.4863602254371052 90 O75880,Q01105,O43819,Q99733,P48643,O43765,O95456,Q99543,P61758,P04792,Q15813,Q96A33,Q9UGP8,Q96KC8,P27824,Q13451,P46379,Q13217,Q9UBS4,O15212 20 +Transferase 0.3040016265623365 1.1276902788178698 0.259450744565515 0.9999999999997778 0.5315767850105168 296 Q03164,O60725,Q08J23,O96028,O60678,Q06203,Q7L7X3,Q92696,P49327,P21964,P23786,P46977,Q9BWD1,O15228,O15269,Q86UY6,Q10472,Q9BV86,Q8NCC3,Q8NF37,P54886,P31939,Q9BRR6,P13807,P51003,Q5VV42,P52789,Q7LGA3,P49356,Q13555,P11802,Q96N66,Q15418,O14936,Q8N6R0,P43490,Q9H7B4,P55263,P51812,P46976,Q02750,O00116,P53396,Q9BT22,Q13126,P35790,O75648,Q15120,Q96PU5,Q9H000,Q96J02,Q86X55,Q9Y6K0,P37268,P31751,Q96G23,Q99943 57 +Receptor 0.5678699535488695 1.0748432428677686 0.2824449163810958 0.9999999999999896 0.5542097592997933 34 Q9NS69,P15260,Q9Y5M8,O15173,Q99720,P30825 6 +Protease inhibitor 0.5570707459011732 1.0083575936284748 0.3132828231984179 1.0 0.5783999645466538 6 P30086 1 +Chloride channel 0.5407276987733365 0.9498227388329368 0.3422023298103989 1.0 0.6136169851046913 4 Q4KMQ2 1 +Protease 0.3887685603223317 0.9116263842532908 0.3619654284034457 1.0 0.6269758313416828 75 P67812,Q8TEY7,Q9NY33,P52888,P55786,P28074,Q16740,Q9UIQ6,Q5JRX3,Q96K76,Q15005,P40818,Q9BYT8,Q8TCT9,P28072,O75844,Q96RU2 17 +Acyltransferase 0.5433330750731283 0.8977388527724977 0.3693247907411634 1.0 0.6285000824893483 28 O15269,Q86UY6,Q8NCC3,Q96N66,Q8NF37,P23786,Q9BWD1,O15228,Q99943 9 +Muscle protein 0.5189673836972817 0.8293118267569182 0.4069279803232881 1.0 0.6805519670923957 6 P60660,P14649 2 +Methyltransferase 0.5099724154342432 0.768858878553016 0.4419770912816143 1.0 0.7266403026155355 37 Q03164,O60725,Q9BV86,Q08J23,O96028,Q8N6R0,P21964,Q9H7B4,Q86X55 9 +Guanine-nucleotide releasing factor 0.4955683447964573 0.6584556435320963 0.5102453903809372 1.0 0.7957183212687221 16 P80303,A4D1U4,Q14155 3 +Endonuclease 0.4316794535264338 0.3630240633847001 0.7165869088027415 1.0 0.967840573946988 17 Q8N2A8,Q9UQ84 2 +tRNA-binding 0.4040597915849248 0.2510439036350391 0.8017801656076395 1.0 0.9900842182545024 17 O75648,Q08J23 2 +Thiol protease 0.3996079507387086 0.1965146721760836 0.8442073498233547 1.0 0.9900842182545024 25 Q96K76,Q8TEY7,P40818,Q96RU2 4 +Glycosyltransferase 0.3955987036328284 0.1693273045552741 0.8655392001406699 1.0 0.9900842182545024 29 Q9BT22,Q06203,Q13126,P46977,P43490 5 +Dioxygenase 0.329704721706189 0.0433512355432209 0.9654215495251266 1.0 1.0 13 Q32P28 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1a64b862b491f2a1fb0779b26ec1ee36d8c73173 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AACS", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABCB1", "ABCC1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APEH", "APEX1", "APLP2", "APOBEC3C", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BANF1", "BAZ1B", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BPNT1", "BPTF", "BRD1", "BRD2", "BSG", "BTF3", "BUB1B", "BZW1", "BZW2", "C12orf43", "CACNA2D1", "CAD", "CALD1", "CALR", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX3", "CBX8", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC37", "CDC42", "CDC5L", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CENPF", "CEP55", "CEPT1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHKA", "CHORDC1", "CHTF18", "CHTOP", "CIRBP", "CKB", "CKMT1A*", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT7", "CNOT9", "CNP", "COLEC12", "COLGALT1", "COMT", "COPA", "COPS5", "CORO1C", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A2", "CSRP2", "CSTB", "CTBP1", "CTBP2", "CTCF", "CTNNB1", "CTPS1", "CTSA", "CTSB", "CTSC", "CUL5", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCPS", "DCTPP1", "DCXR", "DDAH2", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERI1", "ERMP1", "ERO1A", "ERP44", "ESD", "ETFDH", "EWSR1", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "F11R", "FAH", "FAHD1", "FAM120A", "FAM208A", "FAM213A", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLB1L2", "GLDC", "GLO1", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HINT2", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IFNGR1", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA1147", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KRR1", "KYAT3", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD3", "LGALS3", "LIG3", "LIMA1", "LIN28B", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRP1", "LRPAP1", "LRPPRC", "LRSAM1", "LRWD1", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAGED2", "MANBA", "MANF", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL13", "METTL16", "MFN1", "MFN2", "MGAT1", "MGEA5", "MGME1", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA40", "NAA50", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP3", "NCL", "NCOA5", "ND1", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFV2", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NF1", "NHP2", "NIFK", "NIP7", "NIPBL", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OSGEP", "OTUB1", "OXCT1", "P3H1", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDXDC1", "PEBP1", "PECR", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF5A", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIGK", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKCB", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRSS3", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB18", "RAB1A", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REXO2", "REXO4", "RFC1", "RFC3", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRP1B", "RRP8", "RRP9", "RSF1", "RTCB", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30BP", "SARNP", "SARS", "SARS2", "SART3", "SCAF1", "SCAF4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC14L2", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOD2", "SON", "SORD", "SORT1", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAT1", "STAT3", "STAU1", "STMN1", "STRBP", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SWAP70", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCP1", "TECR", "TERF2IP", "TFAM", "TFB1M", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMM50", "TJP1", "TK1", "TKT", "TMCO1", "TMEM109", "TMOD3", "TMPPE", "TMTC3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSNAX", "TSR3", "TST", "TSTA3", "TTLL4", "TTYH3", "TUFM", "TWF1", "TWNK", "TXNDC12", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBLCP1", "UBR1", "UBR4", "UBR5", "UBTF", "UCHL5", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VPS4A", "VPS4B", "VRK1", "WARS", "WARS2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WNK1", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "ZADH2", "ZBTB10", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC3", "ZCRB1", "ZFR", "ZMPSTE24", "ZNF207", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZRANB2"], "leading_proteins": ["ACAD11", "ACAT2", "ACLY", "ACOX1", "ACOX3", "ADK", "ADPGK", "AFG3L2", "AGPAT1", "AGPS", "AIFM1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALG1", "ANO6", "ANXA1", "ARHGEF7", "ATIC", "ATP13A1", "ATP2A2", "ATP2B1", "BAG6", "CAMK2G", "CANX", "CARM1", "CASK", "CCDC47", "CCT5", "CDK4", "CDKAL1", "CEPT1", "CERS2", "CHKA", "CLPP", "COMT", "COX2", "COX4I1", "CPOX", "CPT2", "CYP51A1", "DHCR24", "DNAJB11", "DNAJC1", "DNAJC2", "DNAJC3", "DOHH", "DPP3", "ECE1", "ERAP1", "EXO1", "FASN", "FDFT1", "FKBP5", "FNTB", "FOXRED1", "GALNT1", "GCDH", "GNPAT", "GPX8", "GYG1", "GYS1", "HK2", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSPB1", "ICMT", "IDH1", "IDH2", "IFNGR1", "ITCH", "KDM1B", "KDSR", "KIAA1147", "KMT2A", "LNPEP", "LPCAT1", "LTA4H", "MAP2K1", "MBOAT7", "METTL13", "MKRN2", "MSMO1", "MTAP", "MYL6", "MYL6B", "NAA40", "NAMPT", "NAP1L4", "ND1", "NDUFS2", "NEDD4L", "NLN", "NNT", "NPEPPS", "NSD2", "NSUN2", "NTMT1", "NUCB2", "P3H1", "P4HA1", "PAPOLA", "PCYOX1", "PDK3", "PEBP1", "PECR", "PFDN6", "PGRMC2", "PHGDH", "PITRM1", "PLA2G15", "PLD6", "POR", "PPAT", "PRMT3", "PSMB5", "PSMB6", "PSMG1", "PTGR2", "QSOX2", "RABGGTA", "RDH13", "RPS6KA1", "RPS6KA3", "SCCPDH", "SCO1", "SCO2", "SEC11A", "SEC63", "SET", "SGTA", "SIGMAR1", "SLC7A1", "SMYD3", "SPCS2", "SPTLC1", "SQLE", "SRPRB", "STT3A", "TAOK1", "TBCE", "TECR", "THOP1", "TOMM22", "TRMU", "UQCRFS1", "USP28", "USP33", "USP47", "USP8", "VBP1", "VDAC1", "VDAC2", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a0da9d997edad89e4a04aa9b468aa1d01739cd3b --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "FDA approved drug targets"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..98956e7d11d4126ea579a2949042ae38427069e5 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c10a581ecf22e21e0262a444515db3e7f2e92952e6adfad3b03c9505c5a87051 +size 213581 diff --git a/protein_atlas_protein_class/advanced/plot_1.png b/protein_atlas_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..411723478da5490e28f140b43a210c6749143d03 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d35dc7f90ef2d729365876ea89fc2654947ec4d391df83e38bf64d93fea98f57 +size 210346 diff --git a/protein_atlas_protein_class/advanced/plot_2.png b/protein_atlas_protein_class/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..1c2f2c78d0817e78725184f2d567b291b14323e2 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e329acbca7deb7c51bed43335ac56c356bfbe2a87a65fae70d41d11875f60218 +size 200413 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9147db22105be4325dd0c7ab4563f5342da29d55 --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "FDA approved drug targets", "3": "Metabolic proteins", "4": "Human disease related genes", "5": "Cancer-related genes"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3ab7793e7041da1a1ff9eebe4be53dd0711b0c18 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5ae9168c686774f052752954b798910ef25907f7c0c041fbdb06b941dd8aa50 +size 138795 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..97485ae28ff14b66c47063cc541b3ef788a83249 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:03f6cc512d86d1edae6c90082cf3a21f67d8c0231caf74d481b0b60550024e68 +size 139841 diff --git a/protein_atlas_protein_class/basic/plot_2.png b/protein_atlas_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..4789ef8aaf71890376d83dde2a74fa9782686a84 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5f2b171e9f603f43a5988e98ebe09c6148dc8cce71ddcc2230b80e0fbb3242a +size 145558 diff --git a/protein_atlas_protein_class/basic/plot_3.png b/protein_atlas_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..3fd1fef90e97adf47f583d3f2e2002c93130dc84 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:18d90aec94c4d4cd96a143641d3b084b1140d3e2703f0211f9e0088d8bb348e8 +size 134436 diff --git a/protein_atlas_protein_class/basic/plot_4.png b/protein_atlas_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..b534651855a14e0087c9b567089654fc5f597bc1 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e3d296fb0bdaadaea6f49dd608ea36fffe1382d96b2efa8c9d7d274c87062f2 +size 141552 diff --git a/protein_atlas_protein_class/basic/plot_5.png b/protein_atlas_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..eaa62bccc20c251a8d90f42d36e8795ca450d3d7 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:507e1f663ed8fe8a4ad2574b49b4fceaf1d04d9ce343d65dc56208c46f668f00 +size 142654 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9c2cf5f63f9eb56f3cef34030e261701501ecca1 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0729c431acc86c082fd20e75739d770bafe7f38a81d3fe5a5f63fdb02301d6a5 +size 84831 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ec8cbceb43db60a32e826194851fe5abcf7dcf5a --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 194 472 7.472202936059061 7.88632580918742e-14 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 1.1876590788162938e-17 2.0428617306995395e-10 4.605135540340365e-16 3.7315277707026654e-16 3.3432947379431455e-24 +Transporters 76 328 3.2398804798092296 0.0011957981145043 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 1.0298214062666192e-05 0.451997100673039 0.0027993114703992 2.1690172703538777e-05 2.671109220110293e-09 +FDA approved drug targets 27 109 2.488573095156127 0.0128256869235048 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 0.0006550905750623 0.1692658520693615 0.0005769894192108 0.0009822569935543 0.0003413792750152 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..04125dbb2901f5c3118cffdc7695c3c160a9cb28 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 456.05 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..11e4440f19a9169d1e990c551d654e9d5b39d785 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b32acd2c78c89f2032ac3e785c69d155cd06ca61 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,7 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.625643909045796 7.472202936059061 7.88632580918742e-14 1.5772851618363017e-12 7.886425809187419e-13 472 Q99595,Q9NS69,O60830,Q70HW3,Q9HDC9,O43676,O60725,Q9NQC3,O43169,Q8N511,Q9UIQ6,Q567V2,Q9HD20,Q9BQE5,P03886,P43307,O95197,Q86XL3,Q15392,Q9H1E5,Q9Y487,P30519,O75964,Q9Y282,O15269,Q8N2A8,Q9Y2R0,Q6ZT21,Q96SK2,Q9NPR9,O95831,O00461,O15173,Q9P2W9,Q13423,Q5VW38,P30825,Q9UBX3,Q3SXM5,Q16850,P51648,Q13505,P15260,Q96N66,Q9Y5M8,O95772,Q4ZIN3,Q96A26,Q5BJF2,Q9UDW1,Q8TB61,Q15629,Q8NHS3,Q99720,Q9HD45,O75844,Q9BTX1,O96005,Q8WY22,Q9H4I3,O43772,O95470,Q5SR56,Q9H061,Q15800,P09601,Q8NBX0,Q96GC9,Q9Y6C9,Q96G23,Q6P4A7,P67812,O00264,Q06136,Q9Y619,P01889,Q92804,O43657,Q93050,Q96RQ1,Q8NF37,Q9NZ01,Q96CS3,O15260,Q15070,O43292,Q9NR28,Q15388,P16615,Q8IXU6,O14925,P42858,Q96A33,O14936,O43760,Q15005,Q96KC8,Q8TCT9,Q86UE4,P51812,Q8WVC6,Q07820,Q9BT22,Q00325,Q3ZCQ8,Q9Y6K0,Q9Y3B3,P16435,Q14534,Q99943,O75880,P50402,Q14728,Q9P035,Q6UW68,Q9NZJ7,Q9NX40,Q96ES6,O43819,O14681,Q8NEW0,O76024,P46977,Q99805,Q70UQ0,Q9BUN8,Q96KA5,Q07065,P10321,P00403,Q9UBU6,Q10472,O95070,Q9Y287,P24539,P51003,Q5VV42,Q9H3N1,Q6ZRP7,P53985,Q13555,Q7KZN9,P04843,Q13190,Q8NE01,Q9HC21,Q9NTJ5,Q9UGP8,Q4KMQ2,Q12907,Q8N1F7,P51809,Q15363,O75306,Q8TB36,Q9GZP9,P37268,Q9Y679,Q9Y320,Q01650,P13073,P12235,P62942,O15118,P36551,Q15041,P56134,P20020,Q8IZA0,Q9BXK5,Q96PC5,Q8NCC3,Q9Y4W6,Q6RW13,Q9P0J0,Q8IXB1,P38435,Q9BZF1,Q8N5M9,P49755,P42694,P04439,Q9Y3A6,Q9Y262,Q9UKR5,Q96S97,Q96AG4,Q52LJ0,P35613,P35080,Q92896,P27824,Q9HCU5,Q9BVK6 194 +Transporters 0.4094881056818558 3.2398804798092296 0.0011957981145043 0.023646214425373 0.0059789905725216 328 P13073,P12235,Q70HW3,P04083,Q6UW68,Q8IYU8,Q9NZJ7,P62942,Q8N511,O14681,Q9HD20,Q8NEW0,O43865,O76024,P46977,Q9Y619,Q99805,O95067,P45880,Q9H2D1,Q9BUN8,Q07065,P00403,Q9UBU6,Q93050,Q9Y287,Q8NFH4,Q5VW38,P30825,Q9BPX6,Q9UBX3,O60443,O15260,O60313,Q15070,Q9H3N1,P53985,P16615,Q13555,P04843,Q8IXU6,Q96N66,Q13190,Q8NE01,Q9HC21,Q5BJF2,Q96A33,Q9UGP8,Q96L92,Q4KMQ2,Q8TB61,P40855,Q15629,Q8NHS3,Q99720,Q8N1F7,Q9UJS0,O75844,Q9Y6K0,Q9BTX1,Q15363,O96005,Q8WY22,Q9Y3B3,O43772,Q5SR56,Q9H061,P04080,Q00325,Q9GZP9,P55735,Q96GC9,Q9Y6C9,Q6P4A7,Q9Y320,Q01650 76 +FDA approved drug targets 0.4368658293942019 2.488573095156127 0.0128256869235048 0.2275383558089733 0.0461549820726348 109 P12235,P04083,P62942,P36404,P49327,P03886,P21964,P23786,P20020,P28074,P31939,P68371,Q13423,P38435,P49356,P07437,Q16850,P16615,P15260,O75874,Q16637,Q99720,P49721,Q02750,P53396,P48735,Q14534 27 +Metabolic proteins 0.3011960072640069 1.2758165601146785 0.2020203721936806 0.9890393557631936 0.4489341604304014 787 Q70HW3,O43676,O60725,P52888,Q9NPH0,P03886,P23786,Q9UHG3,Q9H2D1,Q15392,Q9Y487,P30519,O75964,O15269,Q8N2A8,P55786,Q6ZT21,O60502,Q9BRR6,Q13423,P30825,Q9UBX3,Q16850,P51648,Q96N66,Q15418,Q9UDW1,O15254,P43490,Q8TB61,Q9H7B4,Q9Y6M9,O75844,Q9BTX1,O14949,O00116,O43772,O95470,Q15800,P09601,Q13126,P48735,O75648,Q8NBX0,Q96G23,Q9HC38,Q8N4Q0,P67812,Q03164,P07099,Q06136,O43865,P21964,Q9Y619,Q92947,Q96AY3,Q8TEY7,Q93050,Q8NF37,Q9NZ01,Q96K76,Q8NFH4,P40818,O43292,P49356,P47985,P16615,Q06124,Q9NQR4,O96000,O14936,Q15005,P51812,P13674,P46976,Q96RU2,Q9BY49,P53396,O43175,Q9BT22,Q9Y285,Q00325,P55735,Q15120,Q96J02,Q9BYT8,Q9Y6K0,P31751,P16435,Q14534,Q99943,Q9P035,Q9Y217,O43924,Q06203,Q7L7X3,Q8NEW0,P46977,Q709F0,Q9BWD1,P00403,Q86UY6,Q10472,P30154,Q9H7Z7,P24539,P51003,Q7LGA3,P53985,Q13555,P04843,O75874,Q9HC21,Q9NTJ5,Q8NBN7,Q8N6R0,P48449,P30837,P55263,Q8N1F7,Q9UJS0,Q9NXR7,Q02750,Q15067,Q8TED1,O75306,P35790,Q96PU5,Q9H000,Q86X55,P37268,Q01650,P13073,P12235,Q969T7,P62942,O96028,O60678,O15118,P49327,P49589,P36551,P56134,P20020,O15228,Q9Y678,Q8NCC3,P54886,P31939,P13807,Q9P0J0,P52789 152 +Human disease related genes 0.2608929847133462 0.0453960615003702 0.9637916202205056 1.0 1.0 819 Q70HW3,O43676,Q8N511,Q9BQE5,P03886,P23786,Q86XL3,Q15392,Q9Y487,O15269,P68371,O95831,Q13423,Q9BPX6,Q9UBX3,O60443,P07437,Q9BVA1,P51648,P15260,Q96N66,Q8NHS3,Q99720,Q9Y6M9,O75844,O14949,O00116,O43772,O95470,Q9H061,Q15800,P09601,P48735,O75648,Q32P28,Q96CU9,Q6DKK2,Q6P4A7,Q03164,P07099,Q06136,Q08J23,P21964,Q9Y619,P08670,P01889,Q5JTZ9,Q92947,Q96AY3,Q16740,Q9NZ01,O14979,Q7Z4L5,Q8NFH4,Q96HY6,P40818,P04792,O60313,O43292,Q9NR28,P16615,Q06124,Q9Y3Z3,P42858,O96000,O14936,Q16637,P51812,P46976,P55795,Q9BQP7,Q9H3L0,O43175,Q9BT22,Q9Y285,P04080,P35637,Q00325,Q3ZCQ8,Q15120,Q96J02,P31751,P16435,O75880,P50402,O43819,O43924,O76024,P46977,Q96BR5,P10321,P00403,Q5JPH6,P61978,Q9Y287,Q9H7Z7,Q969G3,Q9BW83,O75718,Q5VV42,P53985,Q13555,Q7KZN9,O75874,Q9HC21,Q9Y4P3,Q9Y263,Q9UGP8,Q4KMQ2,P48449,P40855,P55263,Q8N1F7,Q9UJS0,Q02750,Q15067,Q9NVI7,O75306,Q13217,Q8TB36,Q969T9,P38159,Q96PU5,Q9Y320,P12235,Q01105,O96028,O15118,P48643,P49589,P36551,Q15041,P22626,O15228,Q9NXN4,Q9Y4W6,Q16204,Q15042,P54886,P31939,P13807,Q9P0J0,P38435,Q6PGP7,Q15813,P13051,P11802,P08236 148 +Cancer-related genes 0.2558560278689065 0.0160057873528023 0.9872297746472172 1.0 1.0 341 Q99595,Q03164,P04083,Q07021,P50995,P07099,Q01105,Q06136,Q15233,O96028,O14681,P33176,Q9BQE5,P49327,P46977,P49589,P21266,O95067,P05023,P01889,Q5JTZ9,Q92804,P22626,O95684,Q16204,P31939,Q969G3,Q99543,P52789,P40818,P04792,P11802,P04843,Q06124,O75874,P08236,P04439,Q92733,Q15418,P80303,P43490,Q9H7B4,Q8N1F7,P51812,P27824,P67809,Q02750,Q13451,Q92769,P53396,Q07820,P09960,P04080,P35637,P09601,P38159,P48735,Q8IUD2,Q96PU5,Q86X55,P31751,Q92889 62 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d39889db6e28bc5adb6bd3a2a6f48f70dc634879 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOL2", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARL8A", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ARPC4", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATIC", "ATP11C", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "B3GALT6", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1A", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BCS1L", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2orf49", "CAB39", "CACNA2D1", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CENPF", "CENPI", "CEP170", "CEP44", "CEP55", "CEPT1", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP4B", "CHMP5", "CHMP6", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP2L", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COPZ1", "CORO1C", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRKL", "CRNKL1", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPH5", "DPM1", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERG28", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM213A", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD5", "FBL", "FBXO7", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGB1", "GOLIM4", "GOLM1", "GORASP2", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS5", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICE1", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDI1", "IFIT5", "IFNGR1", "IFT27", "IGBP1", "IGF1R", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "IRS4", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1147", "KIAA2013", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LPGAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM12", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAK16", "MANBA", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED24", "MED4", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MLEC", "MMADHC", "MMS19", "MOB4", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS17", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTMR6", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH9", "MYL6", "MYL6B", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPG", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "NDC1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFV2", "NECAP2", "NEDD4L", "NEFM", "NEK9", "NELFCD", "NELFE", "NENF", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NT5DC1", "NT5DC2", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PDZD11", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITHD1", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "PON2", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB10", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB21", "RAB23", "RAB2A", "RAB35", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RIPK1", "RMDN1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL2", "SDAD1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SHTN1", "SIGMAR1", "SIL1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC38A1", "SLC3A2", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX3", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPCS3", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STMN1", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF2", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D10B", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCF25", "TCOF1", "TCP1", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TK1", "TKT", "TLN1", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED4", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM14C", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM33", "TMEM43", "TMEM65", "TMEM97", "TMOD3", "TMPPE", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPAN6", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTLL12", "TTLL4", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "TYMS", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBL5", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UFM1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS16", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR43", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR75", "WDR77", "WDR82", "WFS1", "WIZ", "WNK1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ACAD11", "ACAT2", "ACLY", "ACOX1", "ACOX3", "ACP6", "ADK", "ADPGK", "AFG3L2", "AGPAT1", "AGPS", "AGTRAP", "AHCYL1", "AIFM1", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALG1", "ANKLE2", "ANO6", "ANXA1", "ANXA11", "APMAP", "APOL2", "ARL2", "ARL6IP1", "ATAD3A", "ATIC", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5J2", "ATP5L", "ATP6V0A1", "ATP6V0A2", "AUP1", "BABAM2", "BCL2L13", "BRI3BP", "BSG", "C1QBP", "CAMK2G", "CANX", "CARM1", "CARS", "CASK", "CCDC47", "CCDC6", "CCNB2", "CCT5", "CDK4", "CDKAL1", "CEPT1", "CERS2", "CHKA", "CKAP4", "CLPP", "CLPTM1", "CLPTM1L", "CNNM3", "COA3", "COA7", "COMT", "COPG1", "COX15", "COX2", "COX4I1", "CPOX", "CPT2", "CRTAP", "CSTB", "CYB5B", "CYP51A1", "DCAKD", "DDRGK1", "DERL1", "DERL2", "DHCR24", "DIABLO", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "EARS2", "EI24", "EIF3L", "EMD", "EPHX1", "ERC1", "ERCC4", "ERG28", "ERGIC2", "ERGIC3", "FAF2", "FAM162A", "FAM8A1", "FAM98B", "FARSA", "FASN", "FDFT1", "FGFR1OP", "FKBP10", "FKBP1A", "FKBP5", "FNTB", "FOXRED1", "FUS", "GALNT1", "GCDH", "GDAP1", "GDAP2", "GGCX", "GLG1", "GLOD4", "GNPAT", "GOLIM4", "GPAA1", "GPR107", "GPR108", "GPX8", "GSDME", "GSTM3", "GUSB", "GYG1", "GYS1", "HACD3", "HDAC2", "HELZ", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HS2ST1", "HSDL1", "HSPB1", "HTT", "ICMT", "IDH1", "IDH2", "IFNGR1", "IFT27", "IKBIP", "ITCH", "ITM2B", "JAGN1", "KDSR", "KIAA0319L", "KIF5B", "KMT2A", "LMAN2", "LNPEP", "LPCAT1", "LRRC59", "LSS", "LTA4H", "MAP2K1", "MBOAT7", "MCL1", "METTL13", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MIA2", "MICU1", "MICU2", "MKRN2", "MMADHC", "MPV17L2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTMR6", "MTX1", "MYADM", "NAA40", "NAMPT", "ND1", "NDC1", "NDUFA13", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NEDD4L", "NIT2", "NLN", "NNT", "NONO", "NPC1", "NPEPPS", "NSD2", "NSUN2", "NT5C3B", "NUCB2", "NUP37", "NUP93", "OCIAD1", "OPA1", "OSBPL8", "OXA1L", "P3H1", "P4HA1", "PAPOLA", "PCYOX1", "PDE6D", "PDK3", "PECR", "PEX19", "PFN2", "PGRMC1", "PGRMC2", "PHGDH", "PLA2G15", "PLAA", "PLD6", "POR", "PPAT", "PPP2R1B", "PRCC", "PREB", "PRMT3", "PSMB2", "PSMB5", "PTGES2", "PTPN11", "QSOX2", "RAB3GAP1", "RBMX", "RDH13", "RPN1", "RPS6KA1", "RPS6KA3", "RTN3", "RTN4", "SACM1L", "SAMHD1", "SCCPDH", "SCO1", "SCO2", "SEC11A", "SEC13", "SEC63", "SET", "SFXN4", "SGPL1", "SIGMAR1", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC30A7", "SLC35B2", "SLC35F2", "SLC7A1", "SLC7A5", "SMARCE1", "SMN1*", "SMYD3", "SNX27", "SPCS2", "SPTLC1", "SQLE", "SRPRB", "SSR1", "STARD3NL", "STT3A", "STX18", "STX5", "SURF4", "SYNGR2", "TAF15", "TAOK1", "TBCE", "TBL2", "TECR", "THOP1", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TM9SF2", "TM9SF3", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM126A", "TMEM199", "TMEM205", "TMEM209", "TMEM259", "TMEM97", "TMPPE", "TMX1", "TMX2", "TMX4", "TOMM20", "TOMM22", "TRABD", "TRAM1", "TRMU", "TSPAN6", "TTC19", "TTC21B", "TTC37", "TUBB", "TUBB2B", "TUBB4B", "UNG", "UQCR10", "UQCRFS1", "UQCRQ", "USP28", "USP33", "USP47", "USP8", "VAMP7", "VDAC2", "VIM", "VMP1", "WBP2", "WFS1", "YBX1", "YIF1A", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..35b3d80785c78ccf8aa3e8f4eb1f45055c7dcd06 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Endoplasmic reticulum", "1": "Mitochondria"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..205dada86f0756f83dea388dc0b39134b6bae76b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52a17817e92a15609a07f9aa1a8aacc7e2bc56e76444a286579c242060ac67d2 +size 201848 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_1.png b/protein_atlas_subcellular_location_all/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5015b6e30ff1e82a53e0d42f34011c1abd03236d --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2257141039e9b48e8f24442ee82e107e2217043810648e11294586f275217f0d +size 208357 diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..f3cf9a0508d4f9b4b90f3f1a058119d802cc3f17 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Endoplasmic reticulum", "1": "Mitochondria", "2": "Golgi apparatus", "3": "Vesicles", "4": "Microtubules", "5": "Nuclear membrane", "6": "Centrosome"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png b/protein_atlas_subcellular_location_all/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5babc4d0ec0315faf2fca6d116c80c9e799cde85 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68a7438d243f9b60befb2d035624b26be4377bc57dd77cdab64e1376e326d7ae +size 137825 diff --git a/protein_atlas_subcellular_location_all/basic/plot_1.png b/protein_atlas_subcellular_location_all/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b042ebdd30b59c1a04dd15d205b5de0baf0c4a29 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e83c82e9c53719720df7cb260dab2dfeba21a86199b990958e0533304ff0c08f +size 137780 diff --git a/protein_atlas_subcellular_location_all/basic/plot_2.png b/protein_atlas_subcellular_location_all/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..a809caba6f099d0379b7c7c7dfa34f86255bf18c --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4772d763d8f73d799a0978fe40d93923a8ad6e22fc6fda9bc6abd8821a7e1374 +size 140026 diff --git a/protein_atlas_subcellular_location_all/basic/plot_3.png b/protein_atlas_subcellular_location_all/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..16217a9b0cf092c1fb74e19191ed850b666b41dd --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c7fdac5b98d35263a0afe2a0c30da5f09949a89c899969bdf4d5a61be1c300f9 +size 133857 diff --git a/protein_atlas_subcellular_location_all/basic/plot_4.png b/protein_atlas_subcellular_location_all/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..69147ddb6378dcb871236bef496468b3f497038e --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f50b7b3d255af9a7535e33b1f4d45f231d9c82c145ba6d47895255e0ea6dc1e +size 139146 diff --git a/protein_atlas_subcellular_location_all/basic/plot_5.png b/protein_atlas_subcellular_location_all/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..3a5836f5c5b89ad6a964776dfae9cbe8ac696913 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:190a97784ab060d8879a1464d1d79bee53146bf80f17d594cf95306abeeaf879 +size 145767 diff --git a/protein_atlas_subcellular_location_all/basic/plot_6.png b/protein_atlas_subcellular_location_all/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..2c6eccef61d75c77c6c03e8f33f7026eed433d3b --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78c633a4cfde390d74c8944f8e75acc8a372bec1fbe953352332d0f7ce0d29a6 +size 142447 diff --git a/protein_atlas_subcellular_location_all/consensus.joblib b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..adda7c14a875e99e555f66a6935e50fe24759407 --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cd5fa4891027029680983faf9801493d2821911df7ce6b0f4bbdea91e7d687b7 +size 74271 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db1b15e63f18ed598376a12813a7d2fc91e6a043 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Endoplasmic reticulum 52 175 3.86350333199976 0.000111772368001 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 1.5194758095710045e-07 0.0056186732669075 2.453656014131603e-05 8.602904438030162e-14 2.858508560525609e-18 +Mitochondria 70 347 2.8193070608667465 0.0048127454368454 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 6.563300024994513e-08 0.00190508121096 0.0004500690184254 3.8917193113621366e-10 3.5256473996098876e-10 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..eacff5498572c5295a764e7d560e898d164b763c --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 2812, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 130.66666666666666 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..487835443d06ea014d26550d90c10d1f63e0e397 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C424/C424_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d3e8bfa61b77a8dfda84c0d38b81e89af00f34e3 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,15 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.5012500411716754 3.86350333199976 0.000111772368001 0.0036818994194306 0.0036884881440358 175 P50402,O43852,Q9P035,O00264,Q6UW68,Q9NQC3,O43169,O14681,P21964,P43307,O95197,Q86XL3,Q70UQ0,Q9BUN8,Q96KA5,P84157,O15269,Q8NF37,Q9NZ01,Q96HY6,Q9P2W9,Q96CS3,O15260,Q9H3N1,O43292,Q16850,P51648,P04843,Q4ZIN3,Q5BJF2,Q8WUJ1,Q96A33,Q9UGP8,Q96KC8,Q8TCT9,Q86UE4,Q14257,P13674,P67809,Q92791,Q15293,O96005,Q9BT22,O95470,O15027,Q13217,Q9GZP9,Q15800,P35790,Q96GC9,Q96G23,Q99943 52 +Mitochondria 0.3848932641819101 2.8193070608667465 0.0048127454368454 0.147177644471337 0.0794102997079491 347 Q99595,Q9NS69,O60830,Q70HW3,Q8IYU8,Q9NX40,O43819,Q9NUJ1,Q8N4H5,P23786,Q96BR5,P45880,Q9H2D1,Q5JTZ9,Q92947,O75964,Q96AY3,Q5JPH6,Q9Y2R0,Q6ZT21,P82933,Q16740,Q9H7Z7,P24539,Q5TC12,O95831,Q13423,Q9BPX6,Q9UBX3,O60313,Q15070,O43292,Q3SXM5,Q15388,P47985,Q9NR28,Q7LGA3,Q13505,Q7KZN9,O14925,Q9HC21,Q96A26,Q8NBN7,Q14168,P30837,Q9UJS0,P13674,Q9Y6M9,Q9BQP7,O14949,Q99417,Q9NVI7,Q8WY22,Q9H4I3,O43772,Q07820,O75306,Q8TB36,Q00325,Q5JRX3,Q3ZCQ8,P48735,O75648,Q15120,Q96CU9,Q9BYT8,Q9Y6C9,Q6DKK2,Q6P4A7,Q9Y277 70 +Golgi apparatus 0.357720609430465 1.705778716790882 0.0880492871947391 0.9522410120467376 0.4150894967751988 145 P67812,Q6P179,P50851,P36404,O14681,Q8NEW0,O95067,O00231,Q5BKZ1,Q9Y678,Q9UBU6,Q8IZA0,Q69YN2,Q8TEY7,O95070,Q93050,Q96RQ1,Q6RW13,Q9Y287,Q9NPR9,O95456,O00461,P40818,Q5VW38,O15260,Q6ZRP7,P49755,A4D1U4,P04439,Q8IXU6,Q13190,Q9NTJ5,P80303,O43760,Q92896,Q8TD16,Q9HD45,O15027,P09601,O15212,O14976,Q8N4Q0 42 +Mitotic spindle 0.6599749094673893 1.4776658101752589 0.1394972499786284 0.9929721146865984 0.4671704511697905 18 P07437,Q9BVA1,P68371 3 +Peroxisomes 0.6432382228448715 1.3922378269644229 0.1638503915926135 0.9972749674553542 0.4915511747778405 14 Q9BY49,O15254,O00116,P40855 4 +Cytokinetic bridge 0.6299227955992581 1.327321338035785 0.1844024082503512 0.9988013128583086 0.507106622688466 19 P07437,P68371,Q9BVA1 3 +Vesicles 0.3101069518320034 1.269853753848735 0.2041367289895095 0.9994658425826042 0.5171186235889769 285 P42785,Q96ES6,Q8N8N7,O60506,O15118,Q9HD20,Q7L7X3,P21964,Q8N128,Q5BKZ1,Q9Y487,P30519,Q9Y6A5,P53992,Q8NCC3,O95070,Q93050,Q96RQ1,Q9NRY5,Q96SK2,Q9Y287,Q6RW13,Q9NPR9,Q96K76,P52789,Q9Y5X3,P61758,Q9NUD5,Q9BZF1,Q8N5M9,Q3SXM5,P08236,Q9BPZ3,O95772,Q52LJ0,Q96JB5,Q96L92,P35613,O75312,Q8TB61,Q8NHS3,O75153,Q9HD45,P46976,P13674,O75368,P67809,P51809,Q15363,Q92791,Q9Y4C2,Q9Y679,P55735,Q32P28,Q8NBX0,Q9Y4Z0,Q15369,Q96J02,Q14534,P31751,P16435,Q6P4A7,Q8N4Q0,Q01650 64 +Focal adhesion sites 0.5977356317461451 1.1701506359409626 0.2419403542012188 0.9998927958787468 0.5322687792426815 23 Q9Y487,O60888 2 +Rods & Rings 0.508956950131785 0.802439862768199 0.4222985620133026 0.9999999863159768 0.8709907841524367 4 Q99943 1 +Microtubules 0.4443624241231719 0.4744675531500387 0.635166530607431 0.9999999999999964 1.0 46 P07437,O60830,Q9BVA1,Q9BUF5,P68371 5 +Nuclear membrane 0.3869476076750714 0.3556719568763543 0.7220862486744355 1.0 1.0 61 P67812,P50402,Q14728,Q9BTX1,Q6UW68,Q96G23,Q96SK2,Q99829,O15260,Q9H1E5 10 +Midbody ring 0.4010756450049322 0.3424503740278202 0.7320119844867929 1.0 1.0 4 Q06203 1 +Intermediate filaments 0.3954050886483274 0.1837630880512293 0.8541993144165221 1.0 1.0 24 Q3SXM5,P08670,Q96K76 3 +Centrosome 0.368511543067657 0.1352374378242995 0.8924241478704036 1.0 1.0 55 O95684,P28074,Q9BRR6,Q96DB5,O43292,P49356 6 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..d883ed7776b4847351393454eaf5d635a0f8f969 --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AACS", "AAMP", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABRAXAS2", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPS", "AGTRAP", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK6", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT2", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG5", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOOL", "APPL1", "APRT", "AQR", "ARCN1", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP5", "ARMC6", "ARMCX3", "ARMT1", "ARPC1A", "ARPC2", "ARPC3", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATG9A", "ATIC", "ATP13A1", "ATP1B3", "ATP2B1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN10", "ATXN2L", "AUP1", "BABAM2", "BAG6", "BAIAP2", "BANF1", "BASP1", "BAZ1B", "BCAP31", "BCAS2", "BCCIP", "BCL2L13", "BCLAF1", "BCOR", "BDH2", "BICD2", "BIRC6", "BLMH", "BLVRA", "BLVRB", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRI3BP", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD31", "BYSL", "BZW1", "BZW2", "C11orf58", "C12orf43", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2orf49", "CAB39", "CACYBP", "CAD", "CALD1", "CALR", "CALU", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBFB", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC43", "CCDC47", "CCDC58", "CCDC6", "CCDC8", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC27", "CDC37", "CDC42", "CDC5L", "CDC73", "CDCA2", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CENPF", "CENPI", "CEP170", "CEP55", "CERS2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHEK2", "CHID1", "CHKA", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHTF18", "CHTOP", "CIAPIN1", "CIP2A", "CIRBP", "CISD2", "CKAP2", "CKAP2L", "CKAP5", "CKB", "CLCN3", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG2", "COG7", "COIL", "COLEC12", "COLGALT1", "COMMD4", "COMT", "COPA", "COPB1", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7B", "COPS8", "COTL1", "COX15", "COX4I1", "COX5B", "COX6C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF1", "CPSF2", "CPSF7", "CPT2", "CPVL", "CRKL", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSTB", "CSTF1", "CSTF3", "CTBP1", "CTBP2", "CTCF", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTR9", "CTSA", "CTSB", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWF19L1", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAZAP1", "DBN1", "DBNL", "DBR1", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCXR", "DDA1", "DDAH2", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX10", "DDX17", "DDX18", "DDX19A", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENR", "DERL1", "DERL2", "DFFA", "DHCR7", "DHFR", "DHRS13", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX34", "DHX35", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIMT1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLGAP5", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC17", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DPH5", "DPP3", "DPYSL2", "DR1", "DRG1", "DRG2", "DSG2", "DSP", "DTYMK", "DUSP3", "DUT", "DYNC1H1", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "DYNLL2", "DYNLT1", "EARS2", "EBNA1BP2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EEFSEC", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMOD2", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC4", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERI1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ETFA", "ETFB", "EWSR1", "EXO1", "EXOC6", "EXOC7", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM162A", "FAM177A1", "FAM208A", "FAM208B", "FAM49B", "FAM8A1", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXO7", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP10", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYTTD1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNT2", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDAP2", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA2", "GHITM", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLB1", "GLB1L2", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI2", "GNAI3", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGB1", "GOLIM4", "GOLM1", "GORASP2", "GOT1", "GPAA1", "GPD2", "GPHN", "GPI", "GPR107", "GPR108", "GPS1", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSDME", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GTF2F1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HEXA", "HEXIM1", "HGS", "HIBCH", "HINT2", "HIRIP3", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPB11", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IARS", "IARS2", "IBA57", "ICE1", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFIT5", "IFNGR1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "ILF2", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPAD1", "IMPDH2", "INCENP", "INTS1", "INTS13", "INTS14", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQSEC1", "IRF2BPL", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGB1", "ITM2B", "ITPA", "ITPK1", "IVD", "IWS1", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHDRBS3", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1147", "KIAA2013", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIN", "KLC1", "KMT2A", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMTOR1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG3", "LIMA1", "LIN28B", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRSAM1", "LRWD1", "LSM12", "LSM14A", "LSM2", "LSM4", "LSM6", "LSM7", "LSM8", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZTFL1", "MACF1", "MAD2L1", "MAGED2", "MAK16", "MANBA", "MANF", "MAP1B", "MAP2K1", "MAP2K4", "MAP4", "MAPK1", "MAPK14", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARS", "MAT2A", "MAT2B", "MATR3", "MAU2", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MDC1", "MDH1", "MDH2", "MDN1", "ME2", "MECP2", "MED4", "METTL13", "METTL16", "MFAP1", "MFF", "MFN1", "MFN2", "MFSD10", "MFSD14B", "MFSD3", "MFSD8", "MGEA5", "MGME1", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MKRN2", "MMS19", "MOGS", "MORC2", "MORF4L1", "MORF4L2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH8", "MPI", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL51", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTHFD1L", "MTHFD2", "MTHFS", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MTX3", "MUT", "MXRA7", "MYADM", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NCAPD2", "NCAPD3", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCKAP1", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA9", "NDUFAF1", "NDUFAF2", "NDUFAF4", "NDUFB4", "NDUFB5", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV2", "NECAP2", "NEFM", "NELFCD", "NELFE", "NF1", "NFATC2IP", "NHLRC2", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSUN2", "NSUN5", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B3", "PAICS", "PAIP1", "PAIP2", "PAK1IP1", "PAK2", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PAPSS2", "PARK7", "PARN", "PARP1", "PAWR", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXDC1", "PEBP1", "PECR", "PEF1", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF3", "PHF5A", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIK3C2A", "PIK3R4", "PIN4", "PIR", "PITPNB", "PITRM1", "PKM", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLRG1", "PLS3", "PMPCA", "PMPCB", "PNN", "PNO1", "PNP", "PNPT1", "PODXL", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2H", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POP1", "POP7", "POR", "PPA1", "PPA2", "PPAT", "PPIB", "PPID", "PPIF", "PPIL1", "PPIL4", "PPM1F", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP3CA", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA1", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCB", "PRKCSH", "PRKDC", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRSS3", "PRTFDC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG1", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR2", "PYGB", "PYGL", "PYM1", "QARS", "QKI", "QPRT", "QSOX2", "RAB13", "RAB14", "RAB1A", "RAB23", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM8A", "RBMX", "RBMXL1", "RBPJ", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDX", "RECQL", "REEP5", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOT2", "RIC8A", "RIF1", "RIPK1", "RMDN1", "RNASEH2A", "RNASEH2B", "RNF14", "RNF2", "RNF20", "RNF219", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "RPA1", "RPA2", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS23", "RPS24", "RPS25", "RPS26", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SBNO1", "SCAF1", "SCAF11", "SCAF4", "SCAMP2", "SCAMP3", "SCAMP4", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SDAD1", "SDE2", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC14L2", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3BGRL", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT2", "SHTN1", "SIN3A", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC35B2", "SLC35F2", "SLC3A2", "SLC7A5", "SLC9A3R1", "SLC9A6", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SMYD3", "SNAP23", "SNAP29", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX2", "SNX27", "SNX5", "SNX6", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPC24", "SPC25", "SPCS2", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTLC1", "SQLE", "SQSTM1", "SRCAP", "SREK1", "SRFBP1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STMN1", "STOML2", "STRAP", "STT3B", "STUB1", "STX12", "STX18", "STX4", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SWAP70", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "TAB1", "TACC3", "TAF15", "TAF5", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TARDBP", "TARS", "TARS2", "TBC1D15", "TBC1D4", "TBC1D8B", "TBC1D9B", "TBCA", "TBCB", "TBK1", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TECR", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFG", "TFIP11", "TFRC", "TGOLN2", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TJP1", "TKT", "TLN1", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM115", "TMEM126A", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM259", "TMEM97", "TMOD3", "TMPPE", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO3", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP1", "TOX4", "TP53", "TP53BP1", "TP53BP2", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSNAX", "TSPAN6", "TSPYL1", "TSR1", "TSR3", "TST", "TSTA3", "TTC1", "TTC19", "TTC21B", "TTC27", "TTC37", "TTC38", "TTC4", "TTLL12", "TTLL4", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TXNRD2", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2O", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBFD1", "UBLCP1", "UBQLN4", "UBR1", "UBR4", "UBR5", "UBTF", "UBXN4", "UCHL5", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "URB2", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP24", "USP28", "USP33", "USP36", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VIM", "VIRMA", "VMP1", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS4A", "VPS4B", "VPS50", "VRK1", "VRK3", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR46", "WDR5", "WDR6", "WDR61", "WDR70", "WDR77", "WDR82", "WIZ", "WNK1", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YBX3", "YEATS2", "YIF1A", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZBTB10", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3HAV1", "ZC3HC1", "ZCCHC3", "ZFR", "ZFYVE16", "ZMYM4", "ZMYND8", "ZNF207", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF687", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AARS2", "ABHD10", "ACOX3", "ADPGK", "AGPAT1", "AGPS", "AGTRAP", "AIFM1", "AKT2", "ALDH1B1", "ALDH3A2", "ALG1", "ANKLE2", "ARL2", "ATAD3A", "ATP13A1", "ATP5F1", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATPAF1", "AUP1", "BICD2", "BRI3BP", "BSG", "CALU", "CCDC47", "CCNB2", "CDK5RAP3", "CERS2", "CHKA", "CLPP", "CLPTM1", "CLPTM1L", "CLUH", "COA3", "COA7", "COMT", "COPG1", "COX15", "CPNE1", "CPT2", "CUTA", "CWF19L1", "CYB5B", "CYB5D2", "CYP51A1", "DDRGK1", "DERL1", "DERL2", "DIABLO", "DNAJC1", "DNAJC3", "EARS2", "EI24", "ELOC", "EMD", "ERAP2", "ERGIC2", "FAF2", "FAM114A2", "FAM162A", "FAM177A1", "FAM8A1", "FAM98B", "FGFR1OP", "FKBP10", "FNTB", "FOXRED1", "GAK", "GCDH", "GDAP1", "GLG1", "GOLIM4", "GPAA1", "GPR107", "GPR108", "GUSB", "GYG1", "HACD3", "HK2", "HLA-A", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSDL1", "IDH2", "IKBIP", "ITCH", "ITM2B", "JAGN1", "KIAA0319L", "KIAA1147", "LPCAT1", "LRBA", "LSM4", "MCL1", "MFSD10", "MFSD3", "MFSD8", "MGME1", "MICU1", "MICU2", "MPP2", "MRPS9", "MSMO1", "MTCH2", "MTDH", "MTX1", "MXRA7", "MYCBP", "NDC1", "NDUFB9", "NDUFS2", "NLN", "NNT", "NPC1", "NUCB2", "OCIAD1", "OPA1", "OSBPL8", "OXA1L", "P3H1", "P3H4", "P4HA1", "PAIP2", "PDK3", "PECR", "PEX19", "PFDN6", "PGRMC1", "PITRM1", "PLA2G15", "POR", "PPAT", "PRCP", "PSMB5", "PSMD11", "PSMG1", "PTGES2", "PTGR2", "QSOX2", "RCN1", "RCN2", "RDH13", "RMDN1", "RPN1", "RTN3", "RTN4", "SACM1L", "SCCPDH", "SCO2", "SEC11A", "SEC13", "SEC16A", "SEC24C", "SEC63", "SFXN4", "SGPL1", "SH3BGRL", "SLC25A10", "SLC25A13", "SLC25A19", "SLC25A20", "SLC25A26", "SLC25A3", "SLC25A32", "SLC30A7", "SLC35B2", "SLC35F2", "SLC7A5", "SNX27", "SNX5", "SPTLC1", "SQLE", "SSR1", "STARD3NL", "STX18", "STX5", "SURF4", "SYNCRIP", "SYNGR2", "TACC3", "TAOK1", "TCAF1", "TECR", "TIMM17A", "TIMM17B", "TIMM23", "TIMM50", "TM9SF3", "TMED10", "TMED2", "TMEM205", "TMEM209", "TMEM259", "TMEM97", "TMPPE", "TMX1", "TMX4", "TOMM20", "TOMM22", "TOMM5", "TRABD", "TRMU", "TTC19", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UQCRFS1", "UQCRQ", "USP33", "USP47", "USP8", "VAMP7", "VBP1", "VDAC2", "VDAC3", "VIM", "VMP1", "YBX1", "YIF1A", "ZADH2", "ZCCHC3", "ZNF326", "ZPR1"]} \ No newline at end of file