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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:a00557d94d589367ec942bbd07a3ef716ac70b3d74f67375084e6f2255d7b57e
+size 66672

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2808,
+    "annotations_size": 55,
+    "title": "Average number of proteins per term",
+    "value": 2.3454545454545452
+}

interpro_active_site/paths.json

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+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C427/C427_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Protein-tyrosine phosphatase, active site [IPR016130]	0.7023101297235099	1.300163963845563	0.193544778653552	0.9999927236397296	0.3942578824424207	5	Q06124	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.3354173010748647	0.7176904516193667	0.4729481720082189	0.9999999999999994	0.650303736511301	36	P45985,P19784,Q02750,P11802,O96017,Q99986,Q9NYV4,P51812	8

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine proteases, trypsin family, histidine active site [IPR018114]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "BLMH", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CHEK2", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "GUSB", "HADHB", "HMGCS1", "IGF1R", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K4", "MAPK1", "MDH1", "MDH2", "MTMR6", "NEK9", "NME1", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKACA", "PRKCB", "PRPF4B", "PRSS3", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TXNRD1", "TXNRD2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["CDK12", "CDK4", "CHEK2", "CSNK2A2", "MAP2K1", "MAP2K4", "PTPN11", "RPS6KA3", "VRK1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]", "1": "Protein kinase, ATP binding site [IPR017441]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:c0e614a1e7e38cb6b6b70d8890edb216871ceaceb4a16457ae647e50834c8a92
+size 63410

interpro_binding_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2808,
+    "annotations_size": 31,
+    "title": "Average number of proteins per term",
+    "value": 3.806451612903226
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C427/C427_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,6 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.3707184036632981	0.94604053397887	0.34412791232617	0.999997903988737	0.6068767729384094	32	Q15293,Q96AY3,O43852,P80303,Q14257	5
+Protein kinase, ATP binding site [IPR017441]	0.3690013889231463	0.9299826616109362	0.3523800617061732	0.9999985844456828	0.6068767729384094	31	P45985,P19784,Q02750,P11802,Q96SB4,Q99986,Q9NYV4,P51812	8
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.6627450980392111	0.5047015540011929	0.6137684694213446	0.9999999999998443	0.7046971315578401	3	Q9H0C8,P49593	2
+Peptidase M16, zinc-binding site [IPR001431]	0.3888066883102169	0.2022678628478879	0.8397073224279463	1.0	0.8676975665088779	5	O43847	1
+Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]	0.2868852459016323	0.0244610058843992	0.980484887197264	1.0	0.980484887197264	2	P00505	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APOBEC3C", "ARG2", "BPNT1", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "IGF1R", "ILKAP", "IQGAP1", "IQGAP2", "IQSEC1", "LETM1", "MACF1", "MAP2K1", "MAP2K4", "MAPK1", "MAPK14", "MCCC1", "MICU1", "MYH10", "MYH9", "MYO1B", "MYO1C", "MYO1D", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKAA1", "PRKACA", "PRKCB", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "TAOK1", "TBK1", "TKT", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CDK12", "CDK4", "CSNK2A2", "FKBP10", "GOT2", "ILKAP", "MAP2K1", "MAP2K4", "NRDC", "NUCB2", "PPM1F", "RCN1", "RCN2", "RPS6KA3", "SRPK1", "VRK1"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Zinc finger, RING-type, conserved site [IPR017907]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Zinc finger, RING-type, conserved site [IPR017907]", "1": "Zinc finger, PHD-type, conserved site [IPR019786]", "2": "Bromodomain, conserved site [IPR018359]", "3": "DnaJ domain, conserved site [IPR018253]", "4": "Heat shock protein 70, conserved site [IPR018181]", "5": "WD40 repeat, conserved site [IPR019775]", "6": "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "7": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:b88cd6d2462ea278ca3fabd0c8caac873bfdaa1ce1ed93b6ae2ef36e12298a7e
+size 84318

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Zinc finger, RING-type, conserved site [IPR017907]	10	14	2.3224550639058963	0.0202084453524715	4.609223300970874	14.776699029126211	-0.045326225777209	0.5577732895844865	3.238903742779499	4.550007017672923	0.8841385018499901	0.2924846286854669	1.0	1.0	0.0749593493234848	0.1008932065693596	0.2233586761767504

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 2808,
+    "annotations_size": 259,
+    "title": "Average number of proteins per term",
+    "value": 2.6525096525096523
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C427/C427_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,33 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Zinc finger, RING-type, conserved site [IPR017907]	0.7059674020206437	2.3224550639058963	0.0202084453524715	0.994946105696383	0.1586056771603071	14	O95376,O15344,Q99496,Q9H000,Q99590,Q14258,Q96T88,P19474,Q9UPN9,Q5VTR2	10
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.8338840316462839	1.6275136045666947	0.1036280615880873	0.9999999999995052	0.3354958493914328	4	P48735	1
+Zinc finger, PHD-type, conserved site [IPR019786]	0.5365313805919906	1.469027955525721	0.1418252068786425	1.0	0.3894734402255938	15	Q9NRL2,O96028,Q14839,Q9UIG0,Q9ULU4,O95696,Q9UPN9,P29375,Q9BTC0	9
+Annexin repeat, conserved site [IPR018252]	0.6650156628256575	1.4597426634277484	0.1443608118210695	1.0	0.3894734402255938	7	P50995,P04083,P12429	3
+Intermediate filament protein, conserved site [IPR018039]	0.7212141816193303	1.376439939432785	0.1686854699517868	1.0	0.4283287913481645	5	P07197,Q03252	2
+Bromodomain, conserved site [IPR018359]	0.5938344952870259	1.3559822096201652	0.175104828541641	1.0	0.4319252437360478	9	Q8WWQ0,Q9NRL2,Q9UIG0,P51532,O95696	5
+Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]	0.5882159280467814	1.2200768956562695	0.2224357261719138	1.0	0.4901183900410453	8	P30414	1
+HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]	0.8392729864575887	1.1938681989464035	0.2325295289178508	1.0	0.4901183900410453	2	P52926	1
+DNA topoisomerase, type IIA, conserved site [IPR018522]	0.8157519600855294	1.1010728619223906	0.2708649470934685	1.0	0.5314698583121845	2	P11388	1
+AT hook, DNA-binding motif [IPR017956]	0.8395721925133655	1.091078342147227	0.2752384118398641	1.0	0.5325501561873661	3	P52926,Q6ZRS2	2
+Calreticulin/calnexin, conserved site [IPR018124]	0.7801140413399836	0.9623199888571256	0.3358888911399607	1.0	0.5775120934613766	2	P27797	1
+DnaJ domain, conserved site [IPR018253]	0.5086774318393413	0.9500704363142068	0.3420764638473432	1.0	0.5790706152709928	9	Q9NVH1,Q8WXX5,O60884,Q99543,Q9UBS4	5
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.6250228525262214	0.8258819137155644	0.408871081247625	1.0	0.6496785892216865	4	P42345,P78527	2
+Chromo domain, conserved site [IPR023779]	0.52568814083573	0.7793714386823597	0.4357609433724287	1.0	0.6727265259786059	6	P45973,O14646	2
+ATPase, AAA-type, conserved site [IPR003960]	0.3879222307296814	0.7551404257238777	0.4501647294178288	1.0	0.6856045895624885	17	Q8NBU5,Q6PL18	2
+Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]	0.3953931267001886	0.6240730023767976	0.5325796431680114	1.0	0.7496637368506247	13	P23381	1
+Heat shock protein 70, conserved site [IPR018181]	0.4192280200142875	0.610384423396319	0.5416071840832937	1.0	0.753367071526726	10	P38646,P54652,P48723,Q0VDF9,P34932,Q9Y4L1,P11142,P0DMV9,O95757	9
+WD40 repeat, conserved site [IPR019775]	0.3006182977596409	0.5721149929212415	0.5672440724425274	1.0	0.7651886185552844	45	Q8WWQ0,Q8WUA4,Q96DI7,Q9Y5J1,Q9NV06,Q8NFH4,Q9GZL7,Q9BQ67,Q13347,Q9BZH6,Q8TED0,Q9UMS4,Q9NVX2,P61964,Q9UNX4,Q9GZS3,Q9BV38,Q8NI36	18
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.5050050994270807	0.4162869084938461	0.6772000710862383	1.0	0.8082710525868005	4	Q13363	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.3402496445787843	0.4025737732491589	0.6872618066787772	1.0	0.8165174675679051	14	Q93008,Q8TEY7,Q9P275,Q96RU2	4
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.5923022095509574	0.3284848332489217	0.7425451099938081	1.0	0.8701530572776872	2	P28482	1
+Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]	0.5801853171774718	0.2975159650206756	0.7660726211944344	1.0	0.8818347061749267	2	Q00796	1
+ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]	0.2761168982213301	0.2426367081799405	0.8082868417877538	1.0	0.9141759476988132	20	Q9GZR7,P38919,Q9Y6V7,Q9BUQ8,Q9H0S4,Q13206,Q9NVP1,Q8TDD1,P17844,Q92841,Q86XP3	11
+DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]	0.285244873537204	0.2243135579335315	0.8225133272847129	1.0	0.9182368610635372	15	P18074,Q08211,O60231,Q8IX18,Q14839	5
+Ribosomal protein L24/L26, conserved site [IPR005825]	0.5220955096222324	0.1735286556067943	0.8622359056208118	1.0	0.9422746816700012	2	P61254	1
+Dynamin, GTPase region, conserved site [IPR019762]	0.5138987883107569	0.1594510588945748	0.8733135142534503	1.0	0.9463941430612705	2	P50570	1
+Dynein light chain, type 1/2, conserved site [IPR019763]	0.5085531004989249	0.1507315263172131	0.8801875029502189	1.0	0.9498690136004444	2	Q96FJ2	1
+Ribosomal protein L24e, conserved site [IPR023442]	0.4839629365644982	0.1152562195136204	0.9082420388020014	1.0	0.967140919050031	2	Q9UHA3	1
+14-3-3 protein, conserved site [IPR023409]	0.292875042575616	0.0919510062427383	0.9267369659580292	1.0	0.9757108706631284	6	P61981,Q04917	2
+Cullin, conserved site [IPR016157]	0.2708413508290656	0.0473276664246808	0.9622520781654308	1.0	0.9948406644437932	5	Q13620	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.3889483065953578	0.0447433336638797	0.9643118929967652	1.0	0.9948406644437932	3	P46940,P21359	2
+Ribosomal protein S2, conserved site [IPR018130]	0.3521026372059801	0.0305414377821222	0.9756352462112876	1.0	0.9948406644437932	2	P08865	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class II, conserved site [IPR002011]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AACS", "AAMP", "ABCB1", "ABCB7", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APLP2", "ARHGEF7", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAZ1A", "BAZ1B", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1C", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX35", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSG2", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLB1L2", "GLO1", "GMPPA", "GNPDA1", "GNS", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGA2", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IGF1R", "ILVBL", "IMPAD1", "IMPDH2", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF14", "KIF18A", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME2", "MID1", "MIF", "MKRN2", "MPHOSPH8", "MPI", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NEFM", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSF", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL6", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RCL1", "RDH13", "RDX", "RIDA", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMU1", "SNRNP40", "SNU13", "SORD", "SPTBN1", "SRCAP", "SRM", "STAM", "STMN1", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TUBB", "TUBB2B", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBFD1", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP33", "USP36", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ANXA1", "ANXA11", "ANXA3", "ARIH2", "ATAD1", "ATAD2", "BAZ1A", "BAZ1B", "BRD1", "CALR", "CBX5", "CHD1", "CHD4", "CTBP1", "CUL4B", "DCAF13", "DDX10", "DDX17", "DDX18", "DDX23", "DDX24", "DDX42", "DDX47", "DDX49", "DDX5", "DDX54", "DHX16", "DHX40", "DHX9", "DIDO1", "DNAJA2", "DNAJB11", "DNAJC11", "DNAJC2", "DNAJC9", "DNM2", "DYNLL2", "EIF3I", "EIF4A3", "ERCC2", "GRWD1", "GTF3C2", "HMGA2", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HYOU1", "IDH2", "IQGAP1", "KDM5A", "LMNB2", "MAPK1", "MID1", "MKRN2", "MTOR", "NEFM", "NF1", "NKTR", "NLE1", "NSD2", "NUP37", "PHIP", "PRKDC", "PRPF19", "RNF2", "RNF20", "RPL26", "RPSA", "RSL24D1", "SCAF11", "SMARCA4", "SNRNP40", "SORD", "SRCAP", "TOP2A", "TRIM21", "TRIM25", "TRIM33", "UHRF1", "USP28", "USP33", "USP36", "USP9X", "UTP15", "UTP18", "WARS", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "YWHAG", "YWHAH", "ZMYND8"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Bromodomain [IPR001487]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "Bromodomain [IPR001487]", "2": "Zinc finger, RING-type [IPR001841]", "3": "Zinc finger, PHD-finger [IPR019787]", "4": "Zinc finger, PHD-type [IPR001965]", "5": "Double-stranded RNA-binding domain [IPR014720]", "6": "K Homology domain, type 1 [IPR004088]", "7": "K Homology domain [IPR004087]", "8": "GTP binding domain [IPR006073]", "9": "SAP domain [IPR003034]", "10": "DnaJ domain [IPR001623]", "11": "EF-hand domain [IPR002048]", "12": "Protein kinase domain [IPR000719]", "13": "Helicase, C-terminal [IPR001650]", "14": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "15": "DEAD/DEAH box helicase domain [IPR011545]", "16": "Ubiquitin specific protease domain [IPR028889]", "17": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "18": "SNF2, N-terminal [IPR000330]", "19": "RNA helicase, DEAD-box type, Q motif [IPR014014]", "20": "G-patch domain [IPR000467]", "21": "CS domain [IPR007052]", "22": "ATPase, AAA-type, core [IPR003959]", "23": "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "24": "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]"}