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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +3 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/advanced/plot_0.png +3 -0
  11. interpro_binding_site/basic/idx2term.json +1 -0
  12. interpro_binding_site/basic/plot_0.png +3 -0
  13. interpro_binding_site/consensus.joblib +3 -0
  14. interpro_binding_site/df_merge.tsv +2 -0
  15. interpro_binding_site/metrics.json +7 -0
  16. interpro_binding_site/paths.json +1 -0
  17. interpro_binding_site/result.tsv +4 -0
  18. interpro_binding_site/selections.json +1 -0
  19. interpro_conserved_site/advanced/idx2term.json +1 -0
  20. interpro_conserved_site/advanced/plot_0.png +3 -0
  21. interpro_conserved_site/basic/idx2term.json +1 -0
  22. interpro_conserved_site/basic/plot_0.png +3 -0
  23. interpro_conserved_site/basic/plot_1.png +3 -0
  24. interpro_conserved_site/basic/plot_2.png +3 -0
  25. interpro_conserved_site/consensus.joblib +3 -0
  26. interpro_conserved_site/df_merge.tsv +3 -0
  27. interpro_conserved_site/metrics.json +7 -0
  28. interpro_conserved_site/paths.json +1 -0
  29. interpro_conserved_site/result.tsv +20 -0
  30. interpro_conserved_site/selections.json +1 -0
  31. interpro_domain/advanced/idx2term.json +1 -0
  32. interpro_domain/advanced/plot_0.png +3 -0
  33. interpro_domain/basic/idx2term.json +1 -0
  34. interpro_domain/basic/plot_0.png +3 -0
  35. interpro_domain/basic/plot_1.png +3 -0
  36. interpro_domain/basic/plot_2.png +3 -0
  37. interpro_domain/basic/plot_3.png +3 -0
  38. interpro_domain/consensus.joblib +3 -0
  39. interpro_domain/df_merge.tsv +5 -0
  40. interpro_domain/metrics.json +7 -0
  41. interpro_domain/paths.json +1 -0
  42. interpro_domain/result.tsv +163 -0
  43. interpro_domain/selections.json +0 -0
  44. interpro_family/advanced/idx2term.json +1 -0
  45. interpro_family/advanced/plot_0.png +3 -0
  46. interpro_family/advanced/plot_1.png +3 -0
  47. interpro_family/basic/idx2term.json +1 -0
  48. interpro_family/basic/plot_0.png +3 -0
  49. interpro_family/basic/plot_1.png +3 -0
  50. interpro_family/basic/plot_2.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
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interpro_active_site/basic/idx2term.json ADDED
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interpro_active_site/consensus.joblib ADDED
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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3069,
4
+ "annotations_size": 53,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.509433962264151
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+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C429/C429_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Histidine acid phosphatase active site [IPR033379] 0.956309096837304 1.724629770677571 0.0845942147580705 0.9907631562433432 0.1949344948772928 2 Q9NPH0 1
3
+ Serine carboxypeptidase, serine active site [IPR018202] 0.9037834311806834 1.4555621185797571 0.145513706399109 0.9997599120614268 0.2789343257728267 3 P10619,Q9HB40 2
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
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+ {"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "WNK1"], "leading_proteins": ["ACP6", "CTSA", "SCPEP1"]}
interpro_binding_site/advanced/idx2term.json ADDED
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interpro_binding_site/basic/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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+ EF-Hand 1, calcium-binding site [IPR018247] 11 36 2.0005696921397997 0.0454387824733342 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 0.0011725289770981 0.3175327074700926 0.0413282647695778 0.0028274877976514 0.000386465762899
interpro_binding_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3069,
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+ "annotations_size": 29,
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+ "title": "Average number of proteins per term",
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+ "value": 4.482758620689655
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interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C429/C429_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ EF-Hand 1, calcium-binding site [IPR018247] 0.4971022391563149 2.0005696921397993 0.0454387824733342 0.7403969545709815 0.1197931537933356 36 P41208,Q14257,O43852,Q02818,Q15293,Q9UBV8,Q9BPX6,Q9Y680,P80303,Q6NUK1,Q9NWM8 11
3
+ Peptidase M16, zinc-binding site [IPR001431] 0.6415144088525617 1.144767915265977 0.2523053094983649 0.9997822267145168 0.3723515037763479 5 Q10713 1
4
+ Beta tubulin, autoregulation binding site [IPR013838] 0.640571497773444 1.1406105676417122 0.2540320176560633 0.999796349519712 0.3723515037763479 5 P68371,Q13509,Q13885 3
interpro_binding_site/selections.json ADDED
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TLK2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "FKBP14", "FKBP7", "MICU1", "NUCB1", "NUCB2", "PEF1", "PMPCA", "RCN1", "RCN2", "SLC25A24", "TUBB2A", "TUBB3", "TUBB4B"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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+ Intermediate filament protein, conserved site [IPR018039] 4 8 1.970526575921496 0.0487780522634622 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.0113865203560243 1.0 1.0 0.0683566835720805 0.0096830476876922
interpro_conserved_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3069,
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+ "annotations_size": 271,
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+ "title": "Average number of proteins per term",
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+ "value": 2.7232472324723247
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C429/C429_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Thioredoxin, conserved site [IPR017937] 0.7576286932598842 2.5178749298221743 0.0118065236923783 0.9599891976953148 0.1082597273553034 11 P07237,O43396,Q9H3N1,Q96JJ7,O95881,Q9H1E5 6
3
+ Intermediate filament protein, conserved site [IPR018039] 0.736069057470519 1.970526575921496 0.0487780522634622 0.9999986986782732 0.2033669563599732 8 P07197,P08670,Q16352,P07196 4
4
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.727409881895878 1.92965055722511 0.0536501500113582 0.9999996763948126 0.2138116272511481 8 P49720,P49721,P28074,P28072,Q99436,P28070 6
5
+ Annexin repeat, conserved site [IPR018252] 0.758163039373837 1.851960314167572 0.0640315218910143 0.999999983714866 0.2398110097680421 6 P50995,P09525,P04083,P20073 4
6
+ Haem oxygenase conserved site [IPR018207] 0.9716335180958622 1.7876638366961743 0.0738302595228788 0.9999999990599536 0.2470123497617303 2 P30519 1
7
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.710262062951961 1.7501739974455337 0.080088294232252 0.9999999998503056 0.2578237868082376 7 Q13190,O15400,Q86Y82,Q9P2W9 4
8
+ Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.8774046299315363 1.398721239962846 0.1618965923405217 1.0 0.4220575625247514 2 P13473 1
9
+ Tubulin, conserved site [IPR017975] 0.640571497773444 1.1406105676417122 0.2540320176560633 1.0 0.523242196128547 5 P68371,Q13509,Q13885 3
10
+ Sterol reductase, conserved site [IPR018083] 0.7994783175741756 1.079323783140017 0.2804434142385337 1.0 0.5599344220067329 2 Q9UBM7 1
11
+ Acyl-CoA dehydrogenase, conserved site [IPR006089] 0.5694870415755002 1.078074970796557 0.2810003003428623 1.0 0.5599344220067329 7 Q9H845 1
12
+ Glycoside hydrolase, family 29, conserved site [IPR018526] 0.7835017932833561 1.0149766064920926 0.3101169789217706 1.0 0.5678493330256745 2 Q9BTY2 1
13
+ ABC transporter-like, conserved site [IPR017871] 0.4943149431919973 0.9593988924373076 0.3373578328549842 1.0 0.5932403221186208 10 P08183,Q03519 2
14
+ 14-3-3 protein, conserved site [IPR023409] 0.5380346065948389 0.8395506201017946 0.4011603958199046 1.0 0.6217519270387805 6 P27348,P61981,P63104,P31946,P62258 5
15
+ 4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.6909861556710044 0.6608145256457795 0.5087312662806349 1.0 0.6798947048746072 3 P21912 1
16
+ DnaJ domain, conserved site [IPR018253] 0.4064902681700896 0.4858362530769052 0.6270832683368819 1.0 0.775760125672749 10 Q9NXW2,Q99543,Q96KC8 3
17
+ Acyl-CoA-binding protein, ACBP, conserved site [IPR022408] 0.5553409760220299 0.2560452300031637 0.7979159125731072 1.0 0.866907096293958 3 Q9H3P7 1
18
+ AMP-binding, conserved site [IPR020845] 0.380679034027897 0.2243112890965999 0.8225150925799525 1.0 0.8810339529216091 7 O14975,Q9UKU0 2
19
+ Actin/actin-like conserved site [IPR020902] 0.4527071102413498 0.0751820968271143 0.9400698286977822 1.0 0.979842013758073 3 P61158,P61163 2
20
+ Ribosomal protein S9, conserved site [IPR020574] 0.3322464949461983 0.0338197953611461 0.9730208505586164 1.0 0.9988206458385798 2 P82933 1
interpro_conserved_site/selections.json ADDED
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1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXO3", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NFKB2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIOK2", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ACAD9", "ACBD3", "ACSL6", "ACTR1A", "ACTR3", "ANXA1", "ANXA11", "ANXA4", "ANXA7", "DHCR7", "DNAJB12", "DNAJC1", "DNAJC2", "FUCA2", "HMOX2", "INA", "LAMP2", "MRPS9", "NEFL", "NEFM", "P4HB", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "SDHB", "SLC27A2", "STX12", "STX18", "STX5", "STX7", "TAP2", "TMX1", "TMX3", "TMX4", "TUBB2A", "TUBB3", "TUBB4B", "TXNDC12", "TXNL1", "VIM", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YWHAZ"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "EF-hand domain [IPR002048]"}
interpro_domain/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: 2bcab42d6c14c0ff182507b68fd29660b043e48a9658ebfae856e041a5e3e4d6
  • Pointer size: 131 Bytes
  • Size of remote file: 196 kB
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "EF-hand domain [IPR002048]", "1": "Thioredoxin domain [IPR013766]", "2": "DnaJ domain [IPR001623]", "3": "14-3-3 domain [IPR023410]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 7105fcdead27dc38a8644e250221b1d357e3d94ce96c22bd10192a23e9da11ca
  • Pointer size: 131 Bytes
  • Size of remote file: 132 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: e4ce68f900d89ce4bf4d1d11556981dbfc4b01c9e258d360df4e46dc2e26081a
  • Pointer size: 131 Bytes
  • Size of remote file: 132 kB
interpro_domain/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 12a1650fc088307987170d1ceb875303416786e6a14ca0ec8468207adb5a851c
  • Pointer size: 131 Bytes
  • Size of remote file: 135 kB
interpro_domain/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: 87ea50ac3b795d7d3a27848a8968b24149e85bd503e926c8b033eaf05ca1abc4
  • Pointer size: 131 Bytes
  • Size of remote file: 132 kB
interpro_domain/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:9a4e3be9d282fbe03c9ed8c291b4043226a855f4a706f83c9f635ed1738a5a6f
3
+ size 308561
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,5 @@
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 6 2.5919055754861664 0.0095445964399552 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 8.846999344605528e-06 0.0561990347849709 0.0001833288791406 5.306786809041431e-06 0.0001560226497295
3
+ EF-hand domain [IPR002048] 17 41 2.337729750681419 0.0194012718265783 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 0.0013694726853574 0.3837477700868037 0.0732279741082547 0.002753033778234 8.662957747684397e-05
4
+ ABC transporter type 1, transmembrane domain [IPR011527] 2 6 2.006198485487689 0.0448350754046122 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 0.0592476923069855 1.0 1.0 0.3058660732099017 0.033288888151673
5
+ Intermediate filament, rod domain [IPR039008] 4 8 1.970526575921496 0.0487780522634622 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 0.019872659564244 1.0 1.0 0.0970188007029606 0.0198699646710478
interpro_domain/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3069,
4
+ "annotations_size": 2558,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.168491008600469
7
+ }
interpro_domain/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C429/C429_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,163 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.9312528151053006 2.5919055754861664 0.0095445964399552 0.9999999999778312 0.142846034259594 6 Q9UMX5,O43169,O15173,Q8WUJ1 4
3
+ EF-hand domain [IPR002048] 0.5213470570383968 2.337729750681419 0.0194012718265783 1.0 0.1623804485191817 41 P41208,Q14257,O43852,Q02818,P60660,P30626,Q15293,Q9UBV8,Q9BPX6,Q9Y680,Q8IYU8,P80303,Q6NUK1,Q96AY3,Q8NF37,Q9UJS0,Q9NWM8 17
4
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.7930635780145838 2.006198485487689 0.0448350754046122 1.0 0.2022718216666635 6 P08183,Q03519 2
5
+ Intermediate filament, rod domain [IPR039008] 0.736069057470519 1.970526575921496 0.0487780522634622 1.0 0.2120884085458286 8 P07197,P08670,Q16352,P07196 4
6
+ ERAP1-like C-terminal domain [IPR024571] 0.8880669274920064 1.9643126160533932 0.0494938495190879 1.0 0.2142221101012301 4 P55786 1
7
+ Intermediate filament head, DNA-binding domain [IPR006821] 0.8704730831973858 1.8933383523441336 0.0583128879491203 1.0 0.2294868619819087 4 P08670,Q16352,P07196 3
8
+ LEM domain [IPR003887] 0.7661708648020784 1.8875677239996431 0.0590840065012536 1.0 0.2294868619819087 6 Q86XL3,P50402 2
9
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7659583840110957 1.8866245668086832 0.0592108400735182 1.0 0.2294868619819087 6 P55786 1
10
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7659583840110957 1.8866245668086832 0.0592108400735182 1.0 0.2294868619819087 6 P55786 1
11
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.8079502030620547 1.8690473793847104 0.0616162229450758 1.0 0.2341965799309123 5 P16615,P35670,Q9HD20 3
12
+ GOLD domain [IPR009038] 0.7408864951739478 1.774708883856868 0.0759459676934009 1.0 0.261016695013309 6 Q9H3P7,Q9Y3A6,Q9Y3B3,P49755 4
13
+ GMP phosphodiesterase, delta subunit [IPR008015] 0.9683730029344636 1.7742650017347494 0.0760193267337432 1.0 0.261016695013309 2 O43924 1
14
+ Phospholipid/glycerol acyltransferase [IPR002123] 0.7349024325840512 1.7478173064813116 0.0804956675504864 1.0 0.2667201005105496 6 Q8NF37 1
15
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.9660795825179374 1.6938287786858872 0.0902978237782741 1.0 0.2851298602009429 3 Q15629,Q96G23 2
16
+ MHC class I-like antigen recognition-like [IPR011161] 0.7519362632468208 1.6288561476335597 0.1033434752497606 1.0 0.3093123947751862 5 Q9UNN8,P10321,P55899 3
17
+ FAD-binding domain, PCMH-type [IPR016166] 0.929246820997722 1.613006412309318 0.1067431146791582 1.0 0.3128304746554291 2 Q15392 1
18
+ FAD linked oxidase, N-terminal [IPR006094] 0.929246820997722 1.613006412309318 0.1067431146791582 1.0 0.3128304746554291 2 Q15392 1
19
+ Marvel domain [IPR008253] 0.9263123573524652 1.6008850388455678 0.1094023838779341 1.0 0.3194649520088532 2 O43760 1
20
+ Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.9171829149005616 1.5631592851062663 0.1180151340101056 1.0 0.3335876745734223 2 P51812 1
21
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.6011265485280252 1.542837557293583 0.1228701944024188 1.0 0.3405221639018282 10 Q9H845,O15254,P16219 3
22
+ Peptidase M16, C-terminal [IPR007863] 0.6623737259497906 1.5249005790410353 0.1272838974410213 1.0 0.3467435672567971 7 Q10713,Q5JRX3 2
23
+ Peptidase M16, N-terminal [IPR011765] 0.6623737259497906 1.5249005790410353 0.1272838974410213 1.0 0.3467435672567971 7 Q10713,Q5JRX3 2
24
+ Reticulon [IPR003388] 0.911452806257398 1.4849778037522985 0.137549703983935 1.0 0.3634836185856466 3 O95197 1
25
+ Thioredoxin domain [IPR013766] 0.4716498216660075 1.4442188044058062 0.1486774369710943 1.0 0.3759721977054736 24 P07237,O43819,Q9Y320,O43396,Q9H3N1,Q96JJ7,O95881,Q9H1E5 8
26
+ Immunoglobulin C1-set [IPR003597] 0.7582984072823824 1.4318148657790024 0.1521968116916054 1.0 0.3780906157162544 4 P55899 1
27
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.5798569262531872 1.4281752665626049 0.1532414177634851 1.0 0.3783702187635085 10 Q9Y680,Q9NWM8,P62942 3
28
+ Peptidase M28 [IPR007484] 0.8943730132316128 1.419454556180392 0.155766536666684 1.0 0.3797608298070825 3 Q969V3 1
29
+ Tim10-like [IPR004217] 0.8894324853228879 1.4004943616037493 0.1613653306710434 1.0 0.3870877322325394 3 Q9Y5J9,P62072 2
30
+ Rho GTPase-activating protein domain [IPR000198] 0.6975792229817348 1.391714534000884 0.1640088593709663 1.0 0.3906281771610166 5 O00459 1
31
+ Zinc finger, CHHC-type [IPR012996] 0.8851924331376358 1.3842217908625023 0.166290552973038 1.0 0.3945929819156135 3 P31943,P52597 2
32
+ Band 7 domain [IPR001107] 0.610944766031589 1.3633492118875137 0.172772479296094 1.0 0.4015450948232561 8 O75955,Q99623 2
33
+ Acyl-CoA oxidase, C-terminal [IPR002655] 0.8676230844473434 1.3583343647479793 0.1743576106767523 1.0 0.4024296783510239 2 O15254 1
34
+ ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8672970329312015 1.3569888825539624 0.1747847430211053 1.0 0.4024296783510239 2 Q9NVI7 1
35
+ RBM3/CIRBP, RNA recognition motif [IPR034278] 0.864688620802093 1.3462270322718812 0.1782293096568676 1.0 0.406167338164797 2 Q14011 1
36
+ Glycosyltransferase 2-like [IPR001173] 0.7245017217904883 1.2907124835126256 0.1968033942908653 1.0 0.4337993274141815 4 Q10472 1
37
+ Fibronectin type III [IPR003961] 0.6334075382373053 1.2827629153955706 0.199575150202764 1.0 0.4370832484748891 6 Q15375,Q8NAT1 2
38
+ CBS domain [IPR000644] 0.6306536644000931 1.269963991737675 0.204097456862436 1.0 0.4433913605537037 6 P51790,Q6P4Q7 2
39
+ Glycosyl transferase, family 1 [IPR001296] 0.8369742419302226 1.2321807413219052 0.2178815757122427 1.0 0.4571850633398556 2 Q9BT22 1
40
+ Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.8363221388979423 1.2295057088391386 0.2188822587473056 1.0 0.4585592283993511 2 P13674 1
41
+ Major facilitator superfamily domain [IPR020846] 0.6595979299010055 1.2245169824181272 0.2207572638885024 1.0 0.4609772090014607 5 Q6NT16,Q9H2V7 2
42
+ Cyclic nucleotide-binding domain [IPR000595] 0.6560673810033582 1.2089474376797626 0.2266830396586832 1.0 0.4687592687525558 5 Q6P4Q7 1
43
+ CNNM, transmembrane domain [IPR002550] 0.8268666449299003 1.190773728571409 0.2337424249852127 1.0 0.4741579088914941 2 Q6P4Q7 1
44
+ Ion transporter-like, CBS domain [IPR044751] 0.8268666449299003 1.190773728571409 0.2337424249852127 1.0 0.4741579088914941 2 Q6P4Q7 1
45
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.8257973202097479 1.1567781565395827 0.2473630084030391 1.0 0.4879202272715028 3 Q13505 1
46
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8257973202097479 1.1567781565395827 0.2473630084030391 1.0 0.4879202272715028 3 Q13505 1
47
+ Zinc finger C2H2 AKAP95-type [IPR034736] 0.8251793868232205 1.1544227203085091 0.2483269047487861 1.0 0.4886309402672268 3 Q5BKZ1,O43823 2
48
+ Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.640571497773444 1.1406105676417122 0.2540320176560633 1.0 0.4946076163852457 5 P68371,Q13509,Q13885 3
49
+ Tubulin/FtsZ, GTPase domain [IPR003008] 0.640571497773444 1.1406105676417122 0.2540320176560633 1.0 0.4946076163852457 5 P68371,Q13509,Q13885 3
50
+ CARG-binding factor, N-terminal [IPR012956] 0.8099119660906395 1.1216321158783271 0.2620188906143514 1.0 0.4994369017820499 2 Q99729 1
51
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.8063253994131075 1.1070657855805766 0.2682654868570293 1.0 0.5071863380489882 2 O60506 1
52
+ Protein kinase, C-terminal [IPR017892] 0.567414355738239 1.0680342159846754 0.2855050778201273 1.0 0.5232639395947202 7 P51812 1
53
+ Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075] 0.5475203922724856 1.045585491144918 0.29575245081772 1.0 0.5322321195185131 8 Q9H845 1
54
+ Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786] 0.5475203922724856 1.045585491144918 0.29575245081772 1.0 0.5322321195185131 8 Q9H845 1
55
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.7854581023801777 1.0228241672043483 0.3063909892795187 1.0 0.5425144231655447 2 Q92945 1
56
+ Alpha-L-fucosidase, C-terminal [IPR031919] 0.7835017932833561 1.0149766064920926 0.3101169789217706 1.0 0.5425144231655447 2 Q9BTY2 1
57
+ SUN coiled coil domain 2 [IPR040994] 0.7831757417671998 1.01366960085509 0.3107404341757247 1.0 0.5429467422278033 2 Q9UH99 1
58
+ Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7772341813437584 0.9731116627788972 0.3304978081907967 1.0 0.5607828061492481 3 P16615,P05023 2
59
+ Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7772341813437584 0.9731116627788972 0.3304978081907967 1.0 0.5607828061492481 3 P16615,P05023 2
60
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.4943149431919973 0.9593988924373076 0.3373578328549842 1.0 0.5665780242707555 10 P08183,Q03519 2
61
+ DnaJ domain [IPR001623] 0.4330446345591686 0.9295941051604946 0.3525812807108477 1.0 0.582994373470313 16 Q9NXW2,Q9UGP8,Q8IXB1,Q13217,Q99543,Q96KC8 6
62
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7648401826483904 0.9268779545615212 0.3539899045091972 1.0 0.582994373470313 3 Q9NUQ9,Q96F07 2
63
+ Aldehyde dehydrogenase domain [IPR015590] 0.5020820842062733 0.9044069897331228 0.3657796332017669 1.0 0.5894738647385178 9 P51648 1
64
+ Acyltransferase, C-terminal domain [IPR032098] 0.7555252817828901 0.8923617726593738 0.372199053971074 1.0 0.5924544627302362 3 Q9NUQ2 1
65
+ tRNA synthetases class I, catalytic domain [IPR032678] 0.7505705901532419 0.8845038505080968 0.3764242847819017 1.0 0.5965881787311677 2 Q9HA77 1
66
+ LEM-like domain [IPR013146] 0.7482882295402802 0.875592401833539 0.3812516574903011 1.0 0.5990428377519597 2 P42167 1
67
+ NOPS [IPR012975] 0.746575342465742 0.8594090732486644 0.3901148656596187 1.0 0.6047115581534942 3 Q8WXF1,P23246 2
68
+ Glycoside hydrolase family 20, catalytic domain [IPR015883] 0.7433974567981898 0.8565624268412492 0.391686758284512 1.0 0.6060894077531526 2 P06865 1
69
+ Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019] 0.7433974567981898 0.8565624268412492 0.391686758284512 1.0 0.6060894077531526 2 P06865 1
70
+ AMP-binding enzyme, C-terminal domain [IPR025110] 0.5727720021277349 0.8437843780519353 0.3987899066301632 1.0 0.6108410665628488 5 O14975,Q9UKU0 2
71
+ Legume-like lectin [IPR005052] 0.7398108901206354 0.8426664580449732 0.3994150113456731 1.0 0.6114324350821256 2 Q12907 1
72
+ 14-3-3 domain [IPR023410] 0.5380346065948389 0.8395506201017946 0.4011603958199046 1.0 0.6124261041068949 6 P27348,P61981,P63104,P31946,P62258 5
73
+ Syntaxin, N-terminal domain [IPR006011] 0.6117800532516149 0.8239271619259536 0.4099809458985266 1.0 0.6188277819271378 4 Q86Y82 1
74
+ Survival motor neuron [IPR010304] 0.734920117378552 0.8238020738048565 0.4100520290721261 1.0 0.6188277819271378 2 Q16637 1
75
+ Alpha/beta hydrolase fold-1 [IPR000073] 0.5018900144994529 0.8169553885546611 0.4139539228037028 1.0 0.6228130371676438 8 P38571,Q86WA6,P07099,Q9NUJ1 4
76
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.734181343770372 0.814158872145415 0.415553943116794 1.0 0.6234527780016182 3 O15460,P13674 2
77
+ N-acetylgalactosaminyltransferase [IPR045885] 0.7305840614659848 0.8011163176442405 0.42306431043441 1.0 0.6273883793014013 3 Q10472 1
78
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.725279474781628 0.7819640256407413 0.4342357157084036 1.0 0.6348258246587565 3 P10321 1
79
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.725279474781628 0.7819640256407413 0.4342357157084036 1.0 0.6348258246587565 3 P10321 1
80
+ Fzo/mitofusin HR2 domain [IPR006884] 0.7238343658298194 0.7814286306386921 0.434550437442331 1.0 0.6348258246587565 2 Q8IWA4 1
81
+ Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.5220046673211384 0.7661422745529569 0.4435916513633247 1.0 0.6443540284993665 6 Q13546,Q15375 2
82
+ LRRC8, pannexin-like TM region [IPR021040] 0.708509944571246 0.7238276866517539 0.4691715294770899 1.0 0.6637946750013253 2 Q8TDW0 1
83
+ v-SNARE, coiled-coil homology domain [IPR042855] 0.6943900848010303 0.6726089698845005 0.5011960936399151 1.0 0.6876617469277151 3 O15498,O75396 2
84
+ Longin domain [IPR010908] 0.6943900848010303 0.6726089698845005 0.5011960936399151 1.0 0.6876617469277151 3 O15498,O75396 2
85
+ Proteasome activator PA28, N-terminal domain [IPR003185] 0.6924331376386135 0.6658214107925445 0.5055252578190672 1.0 0.687720898152393 3 Q9UL46,Q06323 2
86
+ Proteasome activator PA28, C-terminal domain [IPR003186] 0.6924331376386135 0.6658214107925445 0.5055252578190672 1.0 0.687720898152393 3 Q9UL46,Q06323 2
87
+ Lamin tail domain [IPR001322] 0.6810176125244516 0.6266064435585686 0.5309172435203573 1.0 0.700766929269904 3 Q03252,P02545 2
88
+ U2A'/phosphoprotein 32 family A, C-terminal [IPR003603] 0.6798092625952186 0.6224949420435282 0.5336164686093057 1.0 0.7021585649777439 3 Q92688 1
89
+ Target SNARE coiled-coil homology domain [IPR000727] 0.4416998501821139 0.5924246939476789 0.5535662344635213 1.0 0.7174302054662266 9 Q13190,O15400,Q86Y82 3
90
+ Chromo domain subgroup [IPR017984] 0.6688259683088735 0.5854927946146619 0.5582164100906106 1.0 0.7214055019975241 3 Q13185 1
91
+ Chromo shadow domain [IPR008251] 0.6688259683088735 0.5854927946146619 0.5582164100906106 1.0 0.7214055019975241 3 Q13185 1
92
+ Exportin-2, central domain [IPR013713] 0.6591650358773485 0.5535283065084404 0.5799017031103575 1.0 0.736172980921238 3 P55060,O15397 2
93
+ AGC-kinase, C-terminal [IPR000961] 0.4155387927203632 0.5328770084468459 0.5941187216387069 1.0 0.7439558641822756 10 P51812 1
94
+ Ricin B, lectin domain [IPR000772] 0.5367241089140664 0.5323106003506884 0.5945108916287567 1.0 0.7439558641822756 4 Q10472 1
95
+ Importin-alpha, importin-beta-binding domain [IPR002652] 0.4954308093994599 0.5213232799188383 0.6021415863242352 1.0 0.7481951326577464 5 O00629,P52292,O60684,O00505 4
96
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.4615927213051235 0.498952080932057 0.617813142596314 1.0 0.7587119798958811 6 O15460,P13674 2
97
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.4615927213051235 0.498952080932057 0.617813142596314 1.0 0.7587119798958811 6 O15460,P13674 2
98
+ Arf GTPase activating protein [IPR001164] 0.6422048271363265 0.4988630120974411 0.6178758929221477 1.0 0.7587119798958811 3 Q8N6H7,Q96P47 2
99
+ EF hand associated, type-1 [IPR013566] 0.6423214867949224 0.4920873466794085 0.6226575968631496 1.0 0.7602664118262228 2 Q8IXI1 1
100
+ MIRO domain [IPR020860] 0.6423214867949224 0.4920873466794085 0.6226575968631496 1.0 0.7602664118262228 2 Q8IXI1 1
101
+ EF hand associated, type-2 [IPR013567] 0.6423214867949224 0.4920873466794085 0.6226575968631496 1.0 0.7602664118262228 2 Q8IXI1 1
102
+ Peptidase M16, middle/third domain [IPR032632] 0.6299315291816059 0.452591835928216 0.6508426786203538 1.0 0.7808573957803737 2 P14735 1
103
+ FAD dependent oxidoreductase [IPR006076] 0.5038909371896734 0.4158180550935867 0.6775431460395804 1.0 0.794635067543756 4 Q9H9P8,Q96CU9 2
104
+ Disulphide isomerase [IPR005788] 0.4507180156657858 0.3528747896454067 0.7241823115263222 1.0 0.8178624074544513 5 P07237,Q15084,P13667,Q8NBS9 4
105
+ GRAM domain [IPR004182] 0.5927885151015121 0.3521208694176346 0.7247476178954357 1.0 0.8181396322049976 3 Q66K14 1
106
+ PTBP1, RNA recognition motif 2-like [IPR021790] 0.4831973898857906 0.347409439767696 0.7282837425633288 1.0 0.8199603052275507 4 Q8WVV9,P14866,Q9UKA9 3
107
+ Putative RNA methylase domain [IPR000241] 0.5908053472448576 0.3380908655372006 0.7352947139156747 1.0 0.8228471874904937 2 Q9BV44 1
108
+ L27 domain, C-terminal [IPR014775] 0.4623164763458427 0.2830776052406732 0.7771173481991331 1.0 0.8477041265216982 4 O14936,Q9NZW5,Q14168 3
109
+ Endonuclease/exonuclease/phosphatase [IPR005135] 0.5609915198956135 0.2695975872438477 0.7874698567381186 1.0 0.852814518855253 3 Q6L8Q7,P27695 2
110
+ Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.561134659276161 0.2630130475235162 0.7925405225989655 1.0 0.8575798040643627 2 Q8WUM0 1
111
+ Zinc finger, RanBP2-type [IPR001876] 0.3821516549084164 0.2600334647226743 0.794837960134803 1.0 0.8597021150210681 8 Q92804 1
112
+ Acyl-CoA-binding protein, ACBP [IPR000582] 0.5553409760220299 0.2560452300031637 0.7979159125731072 1.0 0.8604843610295145 3 Q9H3P7 1
113
+ AP180 N-terminal homology (ANTH) domain [IPR011417] 0.557874144114761 0.2554368707290982 0.7983856963357072 1.0 0.8606281547521024 2 O00291 1
114
+ EGF-like domain [IPR000742] 0.5527515271048232 0.2499524392168463 0.8026241293297145 1.0 0.8644684306633305 3 Q07954 1
115
+ CELF1/2, RNA recognition motif 2 [IPR034198] 0.5500489077274165 0.2378182906403978 0.8120220317335376 1.0 0.8723865422823979 2 Q92879 1
116
+ CELF1/2, RNA recognition motif 3 [IPR034199] 0.5500489077274165 0.2378182906403978 0.8120220317335376 1.0 0.8723865422823979 2 Q92879 1
117
+ CELF1/2, RNA recognition motif 1 [IPR034196] 0.5500489077274165 0.2378182906403978 0.8120220317335376 1.0 0.8723865422823979 2 Q92879 1
118
+ Zinc finger, CCHC-type [IPR001878] 0.3823771483339274 0.2306514649565838 0.8175855821596101 1.0 0.8768905321443533 7 Q16629,Q9NUD5 2
119
+ BAR domain [IPR004148] 0.5424005218525673 0.2263509359718584 0.8209284850304128 1.0 0.8796939221302426 3 Q9Y371,Q99961 2
120
+ AMP-dependent synthetase/ligase [IPR000873] 0.380679034027897 0.2243112890965999 0.8225150925799525 1.0 0.8796939221302426 7 O14975,Q9UKU0 2
121
+ Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108] 0.54352787740462 0.2237516303580447 0.8229505690608563 1.0 0.8796939221302426 2 Q9P2I0 1
122
+ Beta-Casp domain [IPR022712] 0.54352787740462 0.2237516303580447 0.8229505690608563 1.0 0.8796939221302426 2 Q9P2I0 1
123
+ IPT domain [IPR002909] 0.539220349571517 0.2193455746853758 0.8263808627133313 1.0 0.8829917488808278 3 O15031 1
124
+ Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585] 0.5409194652755034 0.2182830978185644 0.8272085429348106 1.0 0.8831383359045265 2 Q13243 1
125
+ MOSC, N-terminal beta barrel [IPR005303] 0.5350505379850019 0.2063114286217456 0.8365476518179282 1.0 0.8908779739176771 2 Q5VT66 1
126
+ Molybdenum cofactor sulfurase, C-terminal [IPR005302] 0.5350505379850019 0.2063114286217456 0.8365476518179282 1.0 0.8908779739176771 2 Q5VT66 1
127
+ Ribosomal L28e/Mak16 [IPR029004] 0.5340723834365727 0.2043610618225529 0.8380713562035751 1.0 0.8920930939487574 2 P46779 1
128
+ Exosome complex component, N-terminal domain [IPR025721] 0.5291816106944824 0.1948023225875251 0.8455477039623238 1.0 0.8978460052866851 2 Q9Y3B2 1
129
+ NET domain [IPR027353] 0.5278774046299279 0.1923077571697552 0.8475011424638237 1.0 0.8988009628617168 2 P25440 1
130
+ Brdt, bromodomain, repeat I [IPR043508] 0.5278774046299279 0.1923077571697552 0.8475011424638237 1.0 0.8988009628617168 2 P25440 1
131
+ Brdt, bromodomain, repeat II [IPR043509] 0.5278774046299279 0.1923077571697552 0.8475011424638237 1.0 0.8988009628617168 2 P25440 1
132
+ Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.5180958591457356 0.1743303303105745 0.8616058640475874 1.0 0.9118691767619896 2 Q86UV5 1
133
+ DNA binding HTH domain, Psq-type [IPR007889] 0.5171177045973262 0.1726036298367989 0.8629629985278511 1.0 0.9129277709819036 2 Q96JN0 1
134
+ Ribosomal protein L10e/L16 [IPR016180] 0.5164656015650428 0.1714596675490922 0.863862341401697 1.0 0.9135013928505752 2 Q9NX20 1
135
+ EF-hand, Ca insensitive [IPR014837] 0.5101108936725293 0.1607630797935219 0.8722800049932768 1.0 0.9197412418684262 3 O43707,P12814 2
136
+ CTP synthase GATase domain [IPR033828] 0.5076622106292674 0.1565766835189247 0.8755784797147712 1.0 0.9213203418800432 2 Q9NRF8 1
137
+ CTP synthase, N-terminal [IPR017456] 0.5076622106292674 0.1565766835189247 0.8755784797147712 1.0 0.9213203418800432 2 Q9NRF8 1
138
+ eRF1 domain 1/Pelota-like [IPR005140] 0.5050537985001522 0.1523667455592498 0.878897684004269 1.0 0.922157619230074 2 P62495 1
139
+ eRF1 domain 3 [IPR005142] 0.5050537985001522 0.1523667455592498 0.878897684004269 1.0 0.922157619230074 2 P62495 1
140
+ eRF1 domain 2 [IPR005141] 0.5050537985001522 0.1523667455592498 0.878897684004269 1.0 0.922157619230074 2 P62495 1
141
+ SGS domain [IPR007699] 0.4867949135963413 0.1254225857636782 0.900189008443139 1.0 0.9383157814314044 2 Q9HB71 1
142
+ Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798] 0.4828822954026739 0.1202147921294594 0.9043130003286766 1.0 0.9411036024575894 2 Q9UKA9 1
143
+ Tudor domain [IPR002999] 0.3347655675771036 0.1118170662320762 0.9109684554892454 1.0 0.9449543021660544 9 Q14739,Q16637,O75940,Q9Y2W6 4
144
+ Cobalamin (vitamin B12)-binding domain [IPR006158] 0.4704923377893677 0.105001868349832 0.916374326188278 1.0 0.9490224803196822 2 Q99707 1
145
+ ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728] 0.4688620802086661 0.1031419633852193 0.917850300637304 1.0 0.9501663573574356 2 Q14240 1
146
+ SUN domain [IPR012919] 0.4697952688879556 0.0965397673094004 0.9230918916598514 1.0 0.9545770375109748 3 Q9UH99 1
147
+ Immunoglobulin I-set [IPR013098] 0.4662746936142824 0.0918605747943012 0.9268088157270442 1.0 0.9550708813668568 3 P10586 1
148
+ Zinc finger, C3HC4 RING-type [IPR018957] 0.4660795825179358 0.0916055318771278 0.9270114561315292 1.0 0.9550708813668568 3 O75150,Q63HN8 2
149
+ Ribosomal protein S10 domain [IPR027486] 0.4506031953048428 0.0844671067281231 0.9326850543817936 1.0 0.9589261933716352 2 P82664 1
150
+ Ubiquitin-associated domain [IPR015940] 0.3254364881303705 0.0785075118592692 0.9374243550680216 1.0 0.9630246989012048 9 Q9UPU5,Q5THJ4,Q9Y5A7 3
151
+ STAG [IPR013721] 0.4254972285621119 0.0647627370868059 0.948362910634546 1.0 0.9721151017926624 2 Q8WVM7 1
152
+ Stromalin conservative domain [IPR020839] 0.4254972285621119 0.0647627370868059 0.948362910634546 1.0 0.9721151017926624 2 Q8WVM7 1
153
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.3380035927081243 0.0640463622043186 0.9489333108585918 1.0 0.9721151017926624 6 Q99956 1
154
+ Peptidase M41 [IPR000642] 0.4206064558200213 0.0616495072599612 0.950841950799526 1.0 0.9730653348428082 2 Q9Y4W6 1
155
+ RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.4091946527551322 0.0552097724899063 0.9559713434908508 1.0 0.9761974836924536 2 O15344 1
156
+ Clp ATPase, C-terminal [IPR019489] 0.394196283012717 0.0483409764535756 0.9614444982221344 1.0 0.9806120520144416 2 Q9H078 1
157
+ Dbl homology (DH) domain [IPR000219] 0.3884540117416827 0.0225918620591698 0.9819758353085136 1.0 0.9948095788986844 3 Q8N5V2,P11274 2
158
+ DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.3685583822570126 0.0136182466853404 0.9891345470706704 1.0 0.997251952833396 3 P20585,P43246 2
159
+ DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.3685583822570126 0.0136182466853404 0.9891345470706704 1.0 0.997251952833396 3 P20585,P43246 2
160
+ DNA mismatch repair protein MutS, connector domain [IPR007860] 0.3685583822570126 0.0136182466853404 0.9891345470706704 1.0 0.997251952833396 3 P20585,P43246 2
161
+ DNA mismatch repair protein MutS, core [IPR007696] 0.3685583822570126 0.0136182466853404 0.9891345470706704 1.0 0.997251952833396 3 P20585,P43246 2
162
+ MRH domain [IPR044865] 0.3568166992824527 0.0095531875797679 0.9923777750621774 1.0 0.9992581467652644 3 P11717,P20645 2
163
+ R3H domain [IPR001374] 0.3222439660795768 0.0016967060959436 0.9986462250513704 1.0 1.0 3 Q9H6S0,O95453 2
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]"}
interpro_family/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: eb27771b83a95be27a6378985263242656a793f14e1261cecb94feab9f31e79b
  • Pointer size: 131 Bytes
  • Size of remote file: 186 kB
interpro_family/advanced/plot_1.png ADDED

Git LFS Details

  • SHA256: 55ff6cfa55b9c82a7ea7faef552f5f5563f33b335835ed79a1f0cf7379dde67a
  • Pointer size: 131 Bytes
  • Size of remote file: 179 kB
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Mitochondrial carrier protein [IPR002067]", "1": "Proteasome B-type subunit [IPR023333]", "2": "Proteasome, subunit alpha/beta [IPR001353]", "3": "14-3-3 protein [IPR000308]", "4": "Short-chain dehydrogenase/reductase SDR [IPR002347]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 9be042239d9ce8bbbe419aa2b29f8729fd95627ac04c514e0369fa301c79a255
  • Pointer size: 131 Bytes
  • Size of remote file: 134 kB
interpro_family/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: 4b856cc3ffda703e7b9936e88dbb9f6808a5cbcec024e9473bca3756a412660c
  • Pointer size: 131 Bytes
  • Size of remote file: 139 kB
interpro_family/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: dae776c39c5c9576a9683f5bcdf2c33e3b39d164e50e7fbd6bac5efefaa4c5fe
  • Pointer size: 131 Bytes
  • Size of remote file: 141 kB