Upload folder using huggingface_hub

interpro_active_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/basic/idx2term.json

@@ -0,0 +1 @@
+{}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:9ff450642c0dd0f68bacea18badc891a899f6fbfce2dd33adc522fc731340005
+size 85078

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3069,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 2.509433962264151
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C431/C431_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.9360939028366532	3.834173863864372	0.0001259870082788	0.0066554855946278	0.0004769508170555	2	Q9NPH0	1
+Serine carboxypeptidase, serine active site [IPR018202]	0.9315068493150628	3.4736268203807215	0.0005134746419424	0.026853988944917	0.0012959121915689	3	Q9HB40,P10619	2

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MDH1", "MDH2", "MTMR2", "NEK9", "NME1", "NME2", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKN1", "PKN2", "PLK1", "PREP", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "VRK1", "WNK1"], "leading_proteins": ["ACP6", "CTSA", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:026af8402957734be59bdba9d306b5f9ff9fa6cf647f463e0a56424abfb836ba
+size 77485

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	8	36	2.196231456029029	0.0280753809620415	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.0008980191984192	0.0551599902794207	0.0072060328618288	0.0001202222452146	0.0003936097898921

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3069,
+    "annotations_size": 29,
+    "title": "Average number of proteins per term",
+    "value": 4.482758620689655
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C431/C431_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.5080154731830914	2.1962314560290292	0.0280753809620415	0.5621302857105652	0.0370084567226911	36	P80303,O43852,Q9NWM8,Q9Y680,Q96AY3,Q02818,Q14257,P41208	8
+Beta tubulin, autoregulation binding site [IPR013838]	0.3756527415143529	0.2547903665640945	0.7988850161457959	1.0	0.7988850161457959	5	Q13885,Q9BVA1,Q13509,P68371	4

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CETN2", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAPK1", "MAPK3", "MCCC1", "MICU1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO5A", "NRDC", "NUCB1", "NUCB2", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDHA", "SDHB", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK4", "TKT", "TLK2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "NUCB1", "NUCB2", "RCN2", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Thioredoxin, conserved site [IPR017937]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Thioredoxin, conserved site [IPR017937]", "1": "Annexin repeat, conserved site [IPR018252]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:4b4f49dedacb8f43fbc5e09fa306aaa283c44938776f88dcca0a4b84b6cd354e
+size 147439

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Thioredoxin, conserved site [IPR017937]	5	11	2.345482218420809	0.0190024849739887	3.905339805825242	10.99514563106796	0.4926509002179139	0.4659055513701703	2.3960466288532025	1.0404329420711995	1.0069927416530815	0.3218319873274993	0.0090696802174768	1.0	0.1277572387780678	0.0442367692127036	2.7323384312904545e-05
+Intermediate filament protein, conserved site [IPR018039]	3	8	2.000162502594784	0.0454827194033091	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.1114782806348729	1.0	1.0	1.0	0.0539281835546241

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3069,
+    "annotations_size": 271,
+    "title": "Average number of proteins per term",
+    "value": 2.7232472324723247
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C431/C431_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,29 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Haem oxygenase conserved site [IPR018207]	0.9918487120965116	4.0888699905216965	4.334797074667662e-05	0.0116788215818454	0.0003263138908986	2	P30519	1
+Lysosome-associated membrane glycoprotein, conserved site [IPR018134]	0.7277469840234823	2.8020105450536383	0.0050785213606467	0.7483675776812335	0.0104263582479945	2	P13473	1
+Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]	0.7416163748685767	2.566538909851281	0.0102719100138992	0.9390732632111148	0.0179334688047885	3	P55899	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.6481904140854218	2.3688348371356125	0.0178442200421253	0.9923988008221726	0.0282794364410291	2	P10644	1
+Thioredoxin, conserved site [IPR017937]	0.7449194505600811	2.345482218420809	0.0190024849739887	0.9944791891353604	0.0294267053025768	11	P07237,O95881,Q9H3N1,Q9H1E5,Q96JJ7	5
+Heat shock protein Hsp90, conserved site [IPR019805]	0.6565557729941223	2.123870061835878	0.0336810104282754	0.9999071762024356	0.048293935587633	3	P14625,P07900	2
+Intermediate filament protein, conserved site [IPR018039]	0.744599901226493	2.0001625025947836	0.0454827194033091	0.9999966779319864	0.0616290847914839	8	P07196,Q16352,P08670	3
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.6827507780880893	1.9921797828651144	0.0463513356351299	0.9999974042807542	0.0624879263385117	4	Q8N4Q0	1
+Histidine triad, conserved site [IPR019808]	0.5686338441473697	1.9113248917783063	0.0559628421497921	0.999999833258754	0.0729131260701619	2	Q96C86	1
+Actin, conserved site [IPR004001]	0.5617867623084397	1.8708046463625576	0.061372163371526	0.9999999648666564	0.0780838322708148	2	P61163	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.7091481818932872	1.8298146186743935	0.0672776640793637	0.999999993648239	0.0851974157266709	8	P49720,P49721,P28070,P28072	4
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7215417370256825	1.7972139596626548	0.0723016592151355	0.9999999985302708	0.0911337192897754	7	Q9P2W9,Q13190,Q86Y82,P56962	4
+Annexin repeat, conserved site [IPR018252]	0.7169441723800349	1.691213822087229	0.0907959720573114	0.9999999999937306	0.1123548330024265	6	P20073,P50995,P08133,P04083,P09525	5
+NUDIX hydrolase, conserved site [IPR020084]	0.5581038569270796	1.5818234787247625	0.1136898735592883	0.9999999999999938	0.1369331365980762	3	Q9BQG2	1
+Actin/actin-like conserved site [IPR020902]	0.5414220482713547	1.4870973267004113	0.136989107498866	1.0	0.1614089049225769	3	P61158,P61163	2
+Guanylate kinase, conserved site [IPR020590]	0.6498219670768343	1.4543940128113473	0.1458370989261719	1.0	0.1710902762294051	7	Q9NZW5,O14936,Q14168	3
+UbiE/COQ5 methyltransferase, conserved site [IPR023576]	0.4365829801108528	1.1034539123075184	0.2698300953851511	1.0	0.3009216290097776	2	Q5HYK3	1
+EGF-like calcium-binding, conserved site [IPR018097]	0.4052820345614597	0.9077427747464984	0.3640141388163329	1.0	0.4026442106907193	2	Q07954	1
+Mrp, conserved site [IPR000808]	0.401369416367789	0.8833737332178885	0.3770343778064524	1.0	0.4153508796160512	2	Q9Y5Y2	1
+Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]	0.4298760600130448	0.8430139245354699	0.3992206562099643	1.0	0.4380113272587057	3	O60568,Q02809	2
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.3805021193348565	0.7542399610561581	0.4507051463381701	1.0	0.4846868835620798	2	O43175	1
+14-3-3 protein, conserved site [IPR023409]	0.5078718312567487	0.7045454130207223	0.4810931792095396	1.0	0.509481711343295	6	P62258,P27348,P63104,P61981	4
+Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]	0.4055745742684065	0.7042427431208546	0.4812816166194964	1.0	0.509481711343295	3	Q9H3P7	1
+Thiosulphate sulfurtransferase, conserved site [IPR001307]	0.3589827192696434	0.6234389063613498	0.5329961376773709	1.0	0.5620309467337257	2	P25325	1
+ABC transporter-like, conserved site [IPR017871]	0.3762910973878655	0.2841421104280537	0.776301476847195	1.0	0.7968852281272342	10	P08183,O15439	2
+Tubulin, conserved site [IPR017975]	0.3756527415143529	0.2547903665640945	0.7988850161457959	1.0	0.816972978775512	5	Q13885,Q9BVA1,Q13509,P68371	4
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.2938682322243965	0.1417740952113068	0.887258446380454	1.0	0.8971904439145636	3	O43175,Q9UBQ7	2
+AMP-binding, conserved site [IPR020845]	0.3452247528265625	0.0718091037223059	0.9427538278039508	1.0	0.9497631499437572	7	Q9UKU0	1

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3'5'-cyclic nucleotide phosphodiesterase, conserved site [IPR023174]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ephrin, conserved site [IPR019765]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Heavy-metal-associated, conserved site [IPR017969]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium/solute symporter, conserved site [IPR018212]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACBD5", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "ARIH2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "ATP7B", "ATR", "BAG6", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BDH2", "BOP1", "BPNT1", "BPTF", "BRD1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDH2", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ5", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1", "DNM1L", "DNM2", "DNM3", "DNMT1", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DUS2", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFNB1", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "ENO1", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXO3", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IVD", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF18A", "KIF18B", "KIF1A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NF1", "NFKB2", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDE8A", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "PPIB", "PPIC", "PPID", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RCL1", "RDH13", "RDX", "RIOK2", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "RTN4IP1", "S100A11", "SART1", "SBDS", "SCAF11", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLC5A6", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX12", "STX17", "STX18", "STX3", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM33", "TRIM4", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TST", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP36", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB1", "ABCC4", "ACBD3", "ACSL6", "ACTR1A", "ACTR3", "ANXA1", "ANXA11", "ANXA4", "ANXA6", "ANXA7", "CASK", "COQ5", "DCPS", "FCGRT", "GRHPR", "HMOX2", "HSP90AA1", "HSP90B1", "INA", "LAMP2", "LRP1", "MPP2", "MPP6", "MPST", "NEFL", "NUBP2", "NUDT12", "P4HB", "PHGDH", "PLOD1", "PLOD3", "PRKAR1A", "PSMB2", "PSMB3", "PSMB4", "PSMB6", "STX12", "STX17", "STX18", "STX5", "TMX1", "TMX3", "TMX4", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4B", "TXNDC12", "VIM", "YWHAE", "YWHAG", "YWHAQ", "YWHAZ", "ZADH2"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-hand domain [IPR002048]", "1": "Thioredoxin domain [IPR013766]", "2": "K Homology domain, type 1 [IPR004088]", "3": "RNA recognition motif domain [IPR000504]", "4": "K Homology domain [IPR004087]", "5": "Immunoglobulin-like domain [IPR007110]", "6": "DnaJ domain [IPR001623]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:6695f6d15599357a4bf026745f31a637035ff80883a517172f63be30c7b80253
+size 909052

interpro_domain/df_merge.tsv

@@ -0,0 +1,8 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	3	10	2.619979001699884	0.0087935181366025	3.1262135922330097	10.111650485436892	0.9686720267359892	0.3700536707457866	1.7316562118191232	1.203619216216406	0.9607394322697528	0.3108814801432357	0.0005835015228144	0.0607401038440192	0.0067896670197663	0.0002054625318554	0.0027630263410089
+EF-hand domain [IPR002048]	10	41	2.4789516016404214	0.0131769184643337	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.0003368775195487	0.0832266786690803	0.0161267578272062	2.961562075578077e-05	0.0003176274883727
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	4	5	2.3267909799320954	0.0199763927278191	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.1551324096650766	1.0	1.0	0.4185863086244521	0.088385561156941
+MHC class I-like antigen recognition-like [IPR011161]	3	5	2.283929058116915	0.0223757005553435	1.6286407766990292	3.3519417475728157	0.7088257141352072	0.3792248400111384	0.978137271268229	0.8617667089672962	1.1217132539816763	0.2987888107271844	0.0090696802174768	1.0	1.0	0.0442367692127036	0.0277461310389573
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	6	2.273909306782594	0.0229714400168798	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0004143495648334	0.0561990347849709	0.0001833288791406	0.0001450038876457	0.0001575214550341
+Cyclic nucleotide-binding domain [IPR000595]	2	5	2.0100991624668234	0.0444206947024183	1.4902912621359223	4.660194174757281	-0.0126471736913758	0.4102849468515657	0.986512397936728	0.870814795980239	1.213781652340298	0.307139032821674	0.27754648329827	1.0	1.0	1.0	0.0105668672564949
+Intermediate filament, rod domain [IPR039008]	3	8	2.000162502594784	0.0454827194033091	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	0.1551324096650766	1.0	1.0	1.0	0.088385561156941

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3069,
+    "annotations_size": 2558,
+    "title": "Average number of proteins per term",
+    "value": 2.168491008600469
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C431/C431_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,192 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Marvel domain [IPR008253]	0.9465275513531132	3.88245791019135	0.0001034059190034	0.2324303218854978	0.0005615973265624	2	O43760	1
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.969341161121982	3.642441112421325	0.0002700647714508	0.4988846605900106	0.0010249639248832	3	Q15629,Q96G23	2
+GMP phosphodiesterase, delta subunit [IPR008015]	0.8793609390283743	3.5663474742399943	0.0003619913357304	0.6039209531968056	0.0012547070959329	2	A6NIH7	1
+Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]	0.8597978480599924	3.4718380027447773	0.0005169081588136	0.7335564637323255	0.0016125013051772	2	P13674	1
+Glycosyl transferase, family 1 [IPR001296]	0.857841538963154	3.462323983803147	0.0005355320750217	0.7459585888465068	0.0016524620601998	2	Q9BT22	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8575154874470146	3.4607371875663184	0.0005386984427973	0.7480090010912906	0.0016542504401866	2	Q9NVI7	1
+Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]	0.8500163025758041	3.4241516386441804	0.0006167219772237	0.7936252277610039	0.0018301331992323	2	Q8TEU7	1
+Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]	0.8500163025758041	3.4241516386441804	0.0006167219772237	0.7936252277610039	0.0018301331992323	2	Q8TEU7	1
+CARG-binding factor, N-terminal [IPR012956]	0.8483860449951068	3.4161755254933652	0.0006350729766491	0.8030947708088627	0.0018629778374637	2	Q99729	1
+Far upstream element-binding protein, C-terminal [IPR015096]	0.8421910661884544	3.3857917169620433	0.0007097322980931	0.8373475854838673	0.0020284862776784	2	Q92945	1
+Choline/carnitine acyltransferase domain [IPR039551]	0.8376263449625128	3.36332764799146	0.0007700890547492	0.8606332994545854	0.0021599646952288	2	P23786	1
+Legume-like lectin [IPR005052]	0.8369742419302371	3.3601132031087664	0.0007791054167736	0.8638132834878047	0.0021828605214752	2	P49257	1
+CNNM, transmembrane domain [IPR002550]	0.829475057059015	3.3230514274881062	0.0008903849771471	0.8975744766904398	0.0023695792870442	2	Q6P4Q7	1
+Ion transporter-like, CBS domain [IPR044751]	0.829475057059015	3.3230514274881062	0.0008903849771471	0.8975744766904398	0.0023695792870442	2	Q6P4Q7	1
+Zinc finger, CHHC-type [IPR012996]	0.8975864318330048	3.319128605644101	0.0009029883209652	0.9008268170491828	0.0023911429865725	3	P52597,P31943	2
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.8249103358330596	3.3004053975925887	0.0009654525680153	0.9154845221051292	0.0025013856612313	2	O60506	1
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.822301923703957	3.2874351540371403	0.0010110447088802	0.9247967368188578	0.0026018635465952	2	Q14011	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.8121943267036352	3.236970115903493	0.0012080606190632	0.9545929161516186	0.0029828369339417	2	P51114	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.8708803410262709	3.1953050868674797	0.001396830973811	0.9720011393649096	0.0033300033839782	3	Q5HYI7	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.8708803410262709	3.1953050868674797	0.001396830973811	0.9720011393649096	0.0033300033839782	3	Q5HYI7	1
+Reticulon [IPR003388]	0.8705153294194286	3.193599017968411	0.0014051114039783	0.9725887706070252	0.0033435116012806	3	O95197,Q9NQC3	2
+Tim10-like [IPR004217]	0.8672537508153835	3.1783377688853673	0.0014812208433911	0.9774443984229042	0.003479304790996	3	P62072,Q9Y5J9	2
+SUN coiled coil domain 2 [IPR040994]	0.7981741115096166	3.1664230869953607	0.0015432615148283	0.9807590071320074	0.003577467291864	2	Q9UH99	1
+Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]	0.8555120678408346	3.123148613500603	0.0017892737622291	0.9897559875365926	0.0040113604590553	3	P13674,O15460	2
+KHDRBS, Qua1 domain [IPR032571]	0.7743723508314373	3.0451690981287545	0.0023254952055644	0.9974085668528836	0.0049366113990322	2	O75525	1
+Sam68, tyrosine-rich domain [IPR032335]	0.7743723508314373	3.0451690981287545	0.0023254952055644	0.9974085668528836	0.0049366113990322	2	O75525	1
+Tim44-like domain [IPR007379]	0.7727420932507292	3.036794277295185	0.0023910858388722	0.9978097107560294	0.0050506998974692	2	O43615	1
+FCP1 homology domain [IPR004274]	0.7698076296054753	3.0216967816431795	0.0025136220046506	0.9984003009407793	0.0052660483930355	2	Q05D32	1
+Fatty acid desaturase domain [IPR005804]	0.7574176719921917	2.957625977752459	0.0031001803982337	0.999644711188134	0.0062149384472429	2	O15121	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.8039791258969265	2.8761994850969677	0.0040249525187359	0.9999669207519764	0.0076668960925618	3	P05023,P16615	2
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.8039791258969265	2.8761994850969677	0.0040249525187359	0.9999669207519764	0.0076668960925618	3	P05023,P16615	2
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.8033268101761191	2.8730228958522948	0.0040656465035644	0.9999702035839964	0.0077265406806224	3	Q5BKZ1,O43823	2
+N-acetylgalactosaminyltransferase [IPR045885]	0.8000652315720738	2.857120547963154	0.0042750344342192	0.9999825989466636	0.0080123314581026	3	Q10471,Q10472	2
+PSI domain [IPR016201]	0.7199217476361377	2.760445387085284	0.0057722608010855	0.9999996294297592	0.0102751865895453	2	O15031	1
+Intermediate filament head, DNA-binding domain [IPR006821]	0.839151712887434	2.748066336184783	0.0059947879032626	0.999999790975846	0.0105537972859917	4	P07196,Q16352,P08670	3
+Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]	0.7055754809259871	2.6836633650857906	0.0072820388372472	0.9999999924037364	0.0123688282507824	2	Q15418	1
+SUN domain [IPR012919]	0.7636629039606607	2.6774084196819787	0.0074194132433735	0.9999999946684044	0.0125604626582062	3	Q9UH99	1
+RBM1CTR [IPR012604]	0.7032931203130265	2.6713783095160575	0.007554045709635	0.9999999962315532	0.0127210328671799	2	P38159	1
+OCRE domain [IPR041591]	0.761904761904747	2.6686237982736607	0.0076162704744968	0.9999999967899856	0.0127920398101282	3	P52756,P98175	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.7026410172807502	2.667864756051302	0.007633497896861	0.999999996929412	0.012804254177161	2	Q8IWA4	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.8269723154678161	2.619979001699884	0.0087935181366025	0.999999999845882	0.0144283639470361	10	P62942,Q9NWM8,Q9Y680	3
+MHC class I, alpha chain, C-terminal [IPR010579]	0.7472105675658851	2.594818883723399	0.0094640775825169	0.9999999999727072	0.0153346399335208	3	P10321	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.7472105675658851	2.594818883723399	0.0094640775825169	0.9999999999727072	0.0153346399335208	3	P10321	1
+Peptidase M28 [IPR007484]	0.7463744886482251	2.5905987100100036	0.0095809140229143	0.999999999979816	0.0154624467322492	3	Q969V3	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7438975972007036	2.5780832056784075	0.0099350072097132	0.9999999999919136	0.0158835927765291	3	P51114	1
+Agenet-like domain [IPR008395]	0.7438975972007036	2.5780832056784075	0.0099350072097132	0.9999999999919136	0.0158835927765291	3	P51114	1
+Fxr1, tudor domain [IPR041560]	0.7438975972007036	2.5780832056784075	0.0099350072097132	0.9999999999919136	0.0158835927765291	3	P51114	1
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7438975972007036	2.5780832056784075	0.0099350072097132	0.9999999999919136	0.0158835927765291	3	P51114	1
+Glycosyltransferase 2-like [IPR001173]	0.791751299919599	2.5263025432722066	0.0115270166122813	0.9999999999998682	0.017946505474264	4	Q10471,Q10472	2
+Survival motor neuron [IPR010304]	0.6755787414411571	2.5206518481837628	0.0117137685222561	0.9999999999999188	0.0181709035051129	2	Q16637	1
+EF-hand domain [IPR002048]	0.5177678281166275	2.4789516016404214	0.0131769184643337	0.999999999999998	0.0200753766716889	41	P80303,O43852,Q9NWM8,Q9Y680,Q66K14,Q96AY3,Q02818,Q14257,Q6NUK1,P41208	10
+Immunoglobulin C1-set [IPR003597]	0.7785967021646998	2.4636492672824377	0.0137530616560179	0.9999999999999996	0.0208044540012383	4	P55899,P10321	2
+ERAP1-like C-terminal domain [IPR024571]	0.7755301794453389	2.448973544988718	0.0143263970170228	1.0	0.0214434895082179	4	Q9UIQ6,Q9NZ08,P55786	3
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.6481904140854218	2.3688348371356125	0.0178442200421253	1.0	0.0258761422152815	2	P10644	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.8045039164490937	2.3267909799320954	0.0199763927278191	1.0	0.0284460614405881	5	P35670,P05023,Q9HD20,P16615	4
+Chromo domain subgroup [IPR017984]	0.6924331376386087	2.31350933723686	0.0206946519920292	1.0	0.0291985216743578	3	P45973,Q13185	2
+Chromo shadow domain [IPR008251]	0.6924331376386087	2.31350933723686	0.0206946519920292	1.0	0.0291985216743578	3	P45973,Q13185	2
+Ras-associating (RA) domain [IPR000159]	0.6915359094166791	2.308819223200183	0.0209536148478117	1.0	0.0294501905388475	3	Q8TEU7	1
+Acyltransferase, C-terminal domain [IPR032098]	0.6888454011741474	2.2947389488225647	0.0217480892672756	1.0	0.0302839479290643	3	Q9NUQ2,Q92604	2
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.6881930854533476	2.2913215411664978	0.0219448236316122	1.0	0.0305080754617739	3	Q9UL46,Q06323	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.6881930854533476	2.2913215411664978	0.0219448236316122	1.0	0.0305080754617739	3	Q9UL46,Q06323	2
+Methyltransferase type 11 [IPR013216]	0.6341701988914203	2.289998636901458	0.0220213956668433	1.0	0.0305812867078096	2	Q6FI81	1
+MHC class I-like antigen recognition-like [IPR011161]	0.7951318932190263	2.283929058116915	0.0223757005553435	1.0	0.0309556744297289	5	Q9UNN8,P55899,P10321	3
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.847433088551318	2.273909306782594	0.0229714400168798	1.0	0.0317283712544161	6	O43169,Q8WUJ1,O15173	3
+Isochorismatase-like [IPR000868]	0.6266710140202312	2.2475163877464444	0.0246070444518984	1.0	0.0336064173560897	2	Q96AB3	1
+CELF1/2, RNA recognition motif 3 [IPR034199]	0.617867623084442	2.1973657505835376	0.0279943352777307	1.0	0.0370649635820058	2	Q92879	1
+CELF1/2, RNA recognition motif 1 [IPR034196]	0.617867623084442	2.1973657505835376	0.0279943352777307	1.0	0.0370649635820058	2	Q92879	1
+CELF1/2, RNA recognition motif 2 [IPR034198]	0.617867623084442	2.1973657505835376	0.0279943352777307	1.0	0.0370649635820058	2	Q92879	1
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.7216042544310662	2.1864948515605893	0.0287794209449121	1.0	0.0380453533731706	4	P21912	1
+NOPS [IPR012975]	0.6647097195042267	2.1673479730633156	0.0302083311235796	1.0	0.039505578228076	3	Q15233,P23246	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.6617742987605821	2.151721552337472	0.0314192916202205	1.0	0.0407558559657829	3	P51809,O15498	2
+Longin domain [IPR010908]	0.6617742987605821	2.151721552337472	0.0314192916202205	1.0	0.0407558559657829	3	P51809,O15498	2
+FKBP3, basic tilted helix bundle domain [IPR041200]	0.6054776654711382	2.12627014504314	0.0334807724191972	1.0	0.0429292310016573	2	Q9ULT8	1
+Disks large homologue 1, N-terminal PEST domain [IPR019590]	0.5983045321160678	2.084835393955611	0.0370842447258257	1.0	0.0469146874424639	2	Q92796	1
+PDZ-associated domain of NMDA receptors [IPR019583]	0.5983045321160678	2.084835393955611	0.0370842447258257	1.0	0.0469146874424639	2	Q92796	1
+Cyclic nucleotide-binding domain [IPR000595]	0.7363647524335005	2.0100991624668234	0.0444206947024183	1.0	0.0548663143644549	5	Q6P4Q7,Q8TEU7	2
+Ricin B, lectin domain [IPR000772]	0.6850810959495661	2.0039566479609467	0.0450747045231285	1.0	0.055486570822985	4	Q10471,Q10472	2
+Intermediate filament, rod domain [IPR039008]	0.744599901226493	2.0001625025947836	0.0454827194033091	1.0	0.0559081192857591	8	P07196,Q16352,P08670	3
+L27 domain, C-terminal [IPR014775]	0.6786296900489354	1.9713148478504663	0.0486878740723981	1.0	0.0593347221901831	4	Q9NZW5,O14936,Q14168	3
+Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]	0.5787414411476935	1.9708142237943276	0.048745129154438	1.0	0.0593762097033583	2	Q8WUM0	1
+EF-hand, Ca insensitive [IPR014837]	0.6200260926288198	1.9263708185579649	0.0540580884520824	1.0	0.0648900001222088	3	O43707,P12814	2
+Heat shock protein DnaJ, cysteine-rich domain [IPR001305]	0.6164846667621835	1.906989937740417	0.056521890513518	1.0	0.0675213864190363	3	O60884	1
+MRH domain [IPR044865]	0.6137470981534824	1.8919803088157656	0.0584936044546982	1.0	0.0695614319828535	3	P11717	1
+LEM domain [IPR003887]	0.7580346356488764	1.8786943763141877	0.0602862361413747	1.0	0.0713284884595913	6	P50402,Q86XL3	2
+RuvB-like, AAA-lid domain [IPR041048]	0.5575480925986258	1.8456321488944325	0.0649456352199338	1.0	0.0764875390849864	2	Q9Y265	1
+TIP49, P-loop domain [IPR010339]	0.5575480925986258	1.8456321488944325	0.0649456352199338	1.0	0.0764875390849864	2	Q9Y265	1
+PITH domain [IPR010400]	0.5568959895663469	1.8417534881488224	0.065511216349861	1.0	0.0769726672875018	2	O43396	1
+PTBP1, RNA recognition motif 2-like [IPR021790]	0.6480932360315133	1.8152176035051648	0.0694904754880814	1.0	0.0808352143240164	4	Q8WVV9	1
+EF hand associated, type-2 [IPR013567]	0.5484186501467192	1.7911873288810105	0.073263238884095	1.0	0.0846465063529878	2	Q8IXI1	1
+MIRO domain [IPR020860]	0.5484186501467192	1.7911873288810105	0.073263238884095	1.0	0.0846465063529878	2	Q8IXI1	1
+EF hand associated, type-1 [IPR013566]	0.5484186501467192	1.7911873288810105	0.073263238884095	1.0	0.0846465063529878	2	Q8IXI1	1
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.5396152592109452	1.7383979617304637	0.0821407156075211	1.0	0.0940536931620586	2	P51784	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.5383110531463919	1.730553581647727	0.083531416776168	1.0	0.0956032949053413	2	P35611	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.6298765759367289	1.7208765252501557	0.0852732321830824	1.0	0.0975095788664841	4	P14625,P07900	2
+L27 domain [IPR004172]	0.67538362548664	1.716860585742895	0.0860046479067697	1.0	0.0983020059631443	5	Q9NZW5,O14936,Q14168	3
+CTP synthase, N-terminal [IPR017456]	0.5337463319204414	1.703050725650037	0.0885585759926499	1.0	0.101085603475769	2	Q9NRF8	1
+CTP synthase GATase domain [IPR033828]	0.5337463319204414	1.703050725650037	0.0885585759926499	1.0	0.101085603475769	2	Q9NRF8	1
+Arfaptin homology (AH) domain [IPR010504]	0.5311379197913164	1.6873019277716226	0.0915453105147872	1.0	0.10435512669199	2	P53365	1
+ABC transporter type 1, transmembrane domain [IPR011527]	0.7122893859233123	1.6697578215459723	0.0949672885312375	1.0	0.1080633114158833	6	P08183,O15439	2
+Band 7 domain [IPR001107]	0.6728543264642118	1.6523115673770223	0.0984710524355327	1.0	0.1119009116526401	8	O75477,O94905	2
+Zinc finger, RanBP2-type [IPR001876]	0.6694621610343955	1.6355689955756152	0.1019298236752548	1.0	0.1154723157490265	8	P35637,P52756,Q92804,P98175	4
+Ribosomal protein S7 domain [IPR023798]	0.5158134985327566	1.5943086059271925	0.1108669310980585	1.0	0.1249879284922141	2	Q9Y2R9	1
+Syntaxin, N-terminal domain [IPR006011]	0.6053111761291774	1.5922906896905462	0.1113194039277689	1.0	0.1253875100163949	4	Q86Y82	1
+Lamin tail domain [IPR001322]	0.5521852576646937	1.5482989001319356	0.1215503491468723	1.0	0.1361321335891854	3	Q03252,P20700	2
+Phospholipid/glycerol acyltransferase [IPR002123]	0.6807233057933544	1.5231676111068468	0.1277167770447356	1.0	0.1426012726671469	6	Q9NUQ2	1
+Domain of unknown function DUF5600 [IPR040990]	0.5024453863710389	1.512564019099342	0.1303904395357875	1.0	0.1454595483351698	2	Q9H223	1
+EH domain-containing protein, N-terminal [IPR031692]	0.5024453863710389	1.512564019099342	0.1303904395357875	1.0	0.1454595483351698	2	Q9H223	1
+Peptidase M41 [IPR000642]	0.4942940984675554	1.462455726979103	0.1436163680649529	1.0	0.1593107846965089	2	Q9Y4W6	1
+Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]	0.5344012755124816	1.4470206023542815	0.1478911534392155	1.0	0.163910559141037	3	O14874	1
+Histidine kinase domain [IPR005467]	0.5344012755124816	1.4470206023542815	0.1478911534392155	1.0	0.163910559141037	3	O14874	1
+FAD dependent oxidoreductase [IPR006076]	0.5756547022381227	1.4351552741472258	0.1512428554907621	1.0	0.167262959077116	4	Q96CU9	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.4877730681447536	1.4222355165061216	0.154957891466509	1.0	0.1710756522966466	2	P62495	1
+eRF1 domain 2 [IPR005141]	0.4877730681447536	1.4222355165061216	0.154957891466509	1.0	0.1710756522966466	2	P62495	1
+eRF1 domain 3 [IPR005142]	0.4877730681447536	1.4222355165061216	0.154957891466509	1.0	0.1710756522966466	2	P62495	1
+Ribosomal L28e/Mak16 [IPR029004]	0.4864688620802002	1.4141779452100982	0.1573096618529785	1.0	0.1735971160569107	2	P46779	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.6536707720476412	1.3961652236271958	0.162664746406882	1.0	0.1791202846787792	6	P13674,O15460	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.6536707720476412	1.3961652236271958	0.162664746406882	1.0	0.1791202846787792	6	P13674,O15460	2
+AP180 N-terminal homology (ANTH) domain [IPR011417]	0.4805999347896935	1.3778658529380674	0.1682447094635981	1.0	0.1850257810867945	2	O00291	1
+Exportin-2, central domain [IPR013713]	0.5215264187866734	1.3732348731145032	0.1696793416705873	1.0	0.1865233158544745	3	O95373,O15397	2
+Thioredoxin domain [IPR013766]	0.4494547772294547	1.3514731349650222	0.1765439200298773	1.0	0.1935702303628058	24	O43819,P07237,O95881,Q9BS26,Q8IXB1,Q9H3N1,Q9H1E5,Q9Y320,Q96JJ7	9
+K Homology domain, type 1 [IPR004088]	0.4552685450119848	1.3446180793470746	0.1787486018394846	1.0	0.1958196674541334	23	Q92667,Q9Y6M1,P51116,Q96I24,Q96AE4,P61978,P51114,Q9Y2W6,Q92945,Q07666,O75525	11
+Arf GTPase activating protein [IPR001164]	0.5140247879973822	1.3300852041311102	0.1834901998825577	1.0	0.2005845860254627	3	Q8N6T3,Q8N6H7	2
+GOLD domain [IPR009038]	0.6336530966054756	1.3015067920974173	0.1930850411585916	1.0	0.2104437730224445	6	Q9H3P7,Q9Y3A6,P49755	3
+Sorting nexin, N-terminal [IPR005329]	0.4626671014020181	1.266433781148287	0.2053578230221169	1.0	0.2227757893513889	2	O60749	1
+Exosome complex component, N-terminal domain [IPR025721]	0.4623410498858673	1.264401948614591	0.2060857938349904	1.0	0.2234707336286162	2	Q9Y3B2	1
+SWIB domain [IPR019835]	0.4584284316921976	1.240006326583867	0.2149730541159162	1.0	0.231830131715225	2	Q92925	1
+SWIB/MDM2 domain [IPR003121]	0.4584284316921976	1.240006326583867	0.2149730541159162	1.0	0.231830131715225	2	Q92925	1
+Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]	0.4548418650146683	1.2176231525807617	0.2233672120244647	1.0	0.2405782435194024	2	Q7Z4V5	1
+Major facilitator superfamily domain [IPR020846]	0.5735533117351947	1.2095817099071688	0.2264394399126117	1.0	0.2437845485254464	5	Q9H2V7,Q6NT16	2
+Ribosomal protein S10 domain [IPR027486]	0.4532116074339702	1.2074431011988291	0.2272615451215052	1.0	0.244566694329327	2	P82664	1
+Man1/Src1, C-terminal [IPR018996]	0.4440821649820515	1.1503787067288376	0.2499879263371447	1.0	0.2685716571064326	2	Q9Y2U8	1
+HDGF-related, PWWP domain [IPR035496]	0.5196070729335116	1.1339509350354224	0.2568151297356769	1.0	0.2757905549386488	4	P51858	1
+RNA recognition motif domain, eukaryote [IPR003954]	0.4882992767390667	1.1137652635832416	0.2653799026492343	1.0	0.284391198565874	14	Q14011,Q9UHX1,P38159	3
+Peptidase M16, C-terminal [IPR007863]	0.5800692669697174	1.1130091582774488	0.2657044961953114	1.0	0.2845006702668927	7	Q5JRX3	1
+Peptidase M16, N-terminal [IPR011765]	0.5800692669697174	1.1130091582774488	0.2657044961953114	1.0	0.2845006702668927	7	Q5JRX3	1
+EGF-like domain [IPR000742]	0.4749531673374545	1.1040133706732944	0.2695873376949362	1.0	0.2882961579530296	3	P07942	1
+SCP2 sterol-binding domain [IPR003033]	0.4726027397260195	1.0903726032361538	0.2755490450966356	1.0	0.2945484568981169	3	Q6YN16,P51659	2
+RNA recognition motif domain [IPR000504]	0.3047339698387938	1.0829404507203224	0.2788348557065827	1.0	0.2978119252181372	120	Q99729,P38159,P51991,P23588,O14979,Q9BWF3,Q8IY67,Q15233,Q13242,Q9UKA9,O43390,P26368,Q8WUA2,Q96PK6,P98179,Q9Y6M1,Q9UHX1,P23246,P31942,P22626,Q92804,P55795,P98175,Q8WVV9,Q8N684,O60506,P07910,Q96I25,Q14103,Q13151,Q14011,P78332,Q01085,P52756,O75494,P35637,P52597,Q07955,P62995,Q93062,Q01844,P31943	42
+Plectin/S10, N-terminal [IPR005326]	0.4300619497880623	1.0626339066294035	0.2879480043550857	1.0	0.3072886921736793	2	P46783	1
+IPT domain [IPR002909]	0.4677126015625938	1.0619901609765152	0.2882401518867654	1.0	0.3074721887099024	3	O15031	1
+Fibronectin type III [IPR003961]	0.5790309351921221	1.0413975101879367	0.2976910976145395	1.0	0.3171569461466022	6	Q8NAT1,Q15375	2
+CS domain [IPR007052]	0.5355659264698385	1.0338871390609108	0.301188928092849	1.0	0.320749907602626	9	Q9P035	1
+Stromalin conservative domain [IPR020839]	0.4225627649168545	1.0156979978357847	0.309773221754666	1.0	0.3296172634144907	2	Q8WVM7	1
+STAG [IPR013721]	0.4225627649168545	1.0156979978357847	0.309773221754666	1.0	0.3296172634144907	2	Q8WVM7	1
+Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]	0.408868601238995	0.9301107132716884	0.3523137644170067	1.0	0.3722505614947142	2	P51784	1
+Zinc finger, C3HC4 RING-type [IPR018957]	0.4432485322896142	0.92017149460923	0.357483147914323	1.0	0.3774006984584557	3	Q5VTR2,O75150	2
+Domain of unknown function DUF4749 [IPR031847]	0.4069122921421576	0.917906795016772	0.3586676639224326	1.0	0.3784950017795308	2	Q96HC4	1
+EGF-like calcium-binding domain [IPR001881]	0.4052820345614597	0.9077427747464984	0.3640141388163329	1.0	0.3836622031694189	2	Q07954	1
+K Homology domain [IPR004087]	0.3988653036630917	0.8794832463330932	0.3791393131023168	1.0	0.399274748009768	22	Q92667,Q9Y6M1,P51116,Q96I24,Q96AE4,P61978,P51114,Q9Y2W6,Q92945,Q07666,O75525	11
+FF domain [IPR002713]	0.3964786436256914	0.852969002649924	0.3936764940535042	1.0	0.4139023722929978	2	O75400	1
+Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]	0.4298760600130448	0.8430139245354699	0.3992206562099643	1.0	0.4195589312181958	3	O60568,Q02809	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.4629690048939445	0.8284486750454646	0.4074164502336166	1.0	0.4279964187669779	4	Q9UNH7,O60749,Q9Y5X3	3
+Target SNARE coiled-coil homology domain [IPR000727]	0.4925065046075294	0.8076917316701275	0.4192680646007143	1.0	0.4400852315341104	9	O15400,Q13190,Q86Y82,P56962	4
+AMP-binding enzyme, C-terminal domain [IPR025110]	0.4920069239274636	0.797264897082842	0.4252972025719002	1.0	0.444953065103853	5	Q9UKU0	1
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.5207447776534627	0.7647654048799961	0.4444112515735754	1.0	0.4636231572288768	6	Q9NZ08,P55786	2
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.5207447776534627	0.7647654048799961	0.4444112515735754	1.0	0.4636231572288768	6	Q9NZ08,P55786	2
+14-3-3 domain [IPR023410]	0.5078718312567487	0.7045454130207223	0.4810931792095396	1.0	0.5016782295487661	6	P62258,P27348,P63104,P61981	4
+Acyl-CoA-binding protein, ACBP [IPR000582]	0.4055745742684065	0.7042427431208546	0.4812816166194964	1.0	0.5016782295487661	3	Q9H3P7	1
+EH domain [IPR000261]	0.4267536704730824	0.6368586261323055	0.5242169345867915	1.0	0.5448788779654663	4	Q9H223,Q96D71,Q9H4M9	3
+Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]	0.3824062382680391	0.5748728103364641	0.5653773197703673	1.0	0.5855203173978136	3	P10586	1
+Importin-alpha, importin-beta-binding domain [IPR002652]	0.4448433420365578	0.5652562354752373	0.5718994916047615	1.0	0.5920351677559611	5	P52292,O00505,O60684,O00629	4
+Immunoglobulin-like domain [IPR007110]	0.4028481795919258	0.5629180100206524	0.5734907157774811	1.0	0.5933650201277254	13	P55899,P04439,P35613,Q08722,P10321	5
+G-patch domain [IPR000467]	0.3872723314282026	0.500187587251156	0.6169429977132139	1.0	0.6366035450384837	14	Q96I25,Q8IWZ8,P98175	3
+BAR domain [IPR004148]	0.3512720156555748	0.408563563399953	0.6828599747389279	1.0	0.6998220414191416	3	Q68EM7,Q9Y371	2
+Aminotransferase, class I/classII [IPR004839]	0.4084929795129589	0.3958700688135934	0.6922008827155821	1.0	0.7088587808013498	5	O15269	1
+Dynamin, N-terminal [IPR045063]	0.4051016753390878	0.3706307718326138	0.7109125592975098	1.0	0.7271148847193243	9	Q8IWA4	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.4051016753390878	0.3706307718326138	0.7109125592975098	1.0	0.7271148847193243	9	Q8IWA4	1
+Septin-type guanine nucleotide-binding (G) domain [IPR030379]	0.3994778067885165	0.3558036413277247	0.7219876219270303	1.0	0.7381472169821517	5	Q9NVA2,Q15019,Q14141,Q9UHD8	4
+tRNA synthetases class I, catalytic domain [IPR032678]	0.3113791979132745	0.3509562615771721	0.7256211619894648	1.0	0.7415656941146828	2	Q9HA77	1
+Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]	0.3022497554613687	0.3028039882316002	0.7620392438597128	1.0	0.7753764462184348	2	Q86YP4	1
+Immunoglobulin subtype 2 [IPR003598]	0.4068045970872432	0.2972070981352642	0.7663084030639811	1.0	0.779100514720852	7	P35613	1
+Chaperone DnaJ, C-terminal [IPR002939]	0.3569331158238139	0.2947597238132748	0.7681774358576505	1.0	0.7806904572601788	4	O60884,Q96EY1,P31689	3
+Guanylate kinase-like domain [IPR008144]	0.3863284406306466	0.2855261858672412	0.7752410455687544	1.0	0.7869311883193943	9	Q9NZW5,O14936,Q14168,Q07157	4
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.3863284406306466	0.2855261858672412	0.7752410455687544	1.0	0.7869311883193943	9	Q9NZW5,O14936,Q14168,Q07157	4
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3762910973878655	0.2841421104280537	0.776301476847195	1.0	0.7876950328342422	10	P08183,O15439	2
+NUDIX hydrolase domain [IPR000086]	0.4050930911447814	0.258259308573602	0.7962067882741584	1.0	0.8069322362936994	6	Q9BQG2	1
+DnaJ domain [IPR001623]	0.3348926743186671	0.2552901587835818	0.798499000338234	1.0	0.808365455419678	16	Q9UGP8,Q13217,O60884,O14976,Q8IXB1,Q9NXW2,Q96KC8	7
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.3756527415143529	0.2547903665640945	0.7988850161457959	1.0	0.808365455419678	5	Q13885,Q9BVA1,Q13509,P68371	4
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.3756527415143529	0.2547903665640945	0.7988850161457959	1.0	0.808365455419678	5	Q13885,Q9BVA1,Q13509,P68371	4
+Zinc finger, CCHC-type [IPR001878]	0.3874145818922317	0.2197049781138502	0.8261009274196447	1.0	0.8339250877424828	7	Q9NUD5	1
+D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]	0.2938682322243965	0.1417740952113068	0.887258446380454	1.0	0.8935461046618903	3	O43175,Q9UBQ7	2
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]	0.2938682322243965	0.1417740952113068	0.887258446380454	1.0	0.8935461046618903	3	O43175,Q9UBQ7	2
+Alpha/beta hydrolase fold-1 [IPR000073]	0.3575630619867718	0.1360682056366261	0.8917673619486084	1.0	0.8977335347754979	8	Q9NUJ1,P07099	2
+Rhodanese-like domain [IPR001763]	0.3162209110005513	0.1275506011581971	0.8985046262624135	1.0	0.904160044838416	4	Q99956	1
+Tyrosine-specific protein phosphatases domain [IPR000387]	0.362339263055029	0.1066897861313234	0.9150350858416064	1.0	0.9204324614954106	6	Q99956,P10586	2
+VHS domain [IPR002014]	0.3022498769998707	0.0782754086239246	0.9376089785072784	1.0	0.9427687763449758	4	O14964,Q92783	2
+AMP-dependent synthetase/ligase [IPR000873]	0.3452247528265625	0.0718091037223059	0.9427538278039508	1.0	0.9475694662170948	7	Q9UKU0	1
+Dynamin, GTPase domain [IPR001401]	0.3214751958224607	0.0599328558048448	0.9522091117708948	1.0	0.9566971358640806	5	P50570,O60313,O00429,Q05193	4
+CBS domain [IPR000644]	0.3389341247034513	0.0370167125073882	0.9704716802186996	1.0	0.9746629595600448	6	Q8NE01,Q6P4Q7	2
+Rho GTPase-activating protein domain [IPR000198]	0.3116667880598639	0.0310353704650637	0.975241331698617	1.0	0.9790688094525364	5	O00459	1
+Protein-tyrosine phosphatase, catalytic [IPR003595]	0.3089789216610455	0.0234979346266378	0.9812530859604492	1.0	0.9847176908147622	5	P10586	1

interpro_family/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]"}

interpro_family/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Mitochondrial carrier protein [IPR002067]", "1": "Annexin [IPR001464]"}