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term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size
Lysosomal lumen 25 36 3.867768992233733 0.000109835639906 Q14108,P61916,P50897,P10253,P38435,P10619,P06280,P07602,P54802,Q8NHP8,Q8IV08,P16278,Q9UM22,Q13510,O00754,P46976,P11117,P04062,P17900,P15586,P13473,O14773,P06865,P08236,O00584 Localization GO Cellular component msigdb_gocc 130,256,6,144,145,25,156,36,40,44,175,179,53,313,66,331,79,213,89,218,217,121,99,246,249 249,66,121,811,213,1422,156,99,36,918,661,246,144,25,79,1584,217,730,218,179,89,145,3391,331,6,40,256,313,130,175,2134,44,381,804,652,53 1.3177131892594451,2.8070566341243905,2.0442894948035293,0.3438753282799643,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,0.4785567416325205,1.338473936006947,1.8863625663085712,4.1354813465701925,2.5638146678084146,-0.09381103021537567,1.4623099427802935,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,1.8863625663085712,-1.9788713010588765,1.0232798624432902,5.121449989369716,3.370732425976295,1.296917258531428,1.0869803140135814,1.9852909461843653,1.6861990067024655,-0.30754673593761184,3.281295714487462,0.937812905361756,0.36643501064183787,0.5008477318133796,3.0643705285634333 3430
Sphingolipid metabolic process 14 28 3.3835908688676 0.0007154452807613 P17900,P06865,P07602,Q96G23,P50897,Q8NCC3,P27544,O95470,O60512,P16278,P04062,Q13510,Q06136,P06280 Processes and pathways GO Biological process msigdb_gobp 89,99,36,68,6,108,82,147,150,179,213,313,59,156 548,1633,150,147,213,156,99,36,918,179,89,1649,82,532,6,1824,59,617,313,1305,108,68,381,1278,2972,652,1688,1973 0.6116509767559337,-0.11734646334023954,1.8465787199040886,1.866485968870282,1.4828295622266432,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,1.6457867663301875,2.431035510324411,-0.11734646334023954,2.54492504446314,0.6336831437767028,5.121449989369716,-0.18826843715602568,2.8625913164326255,0.5230949161824157,1.0869803140135814,0.04632210615831087,2.1809317216381077,2.7884960733515816,0.937812905361756,0.06950099771551356,-0.7237852836123975,0.5008477318133796,-0.11734646334023954,-0.23581657417804916 3430
Lysosome 26 50 3.358467713953567 0.0007837587630636 Q14108,P61916,P50897,O75503,P10253,Q9Y487,P10619,P06280,P07602,O15118,P54802,Q93050,P16278,Q13510,O00754,Q99523,P11117,P04062,P17900,P15586,P13473,P06865,Q9Y2T2,Q8NCC3,P08236,O14773 Processes and pathways KEGG Pathways msigdb_kegg 130,256,6,138,144,24,25,156,36,164,40,45,179,313,66,78,79,213,89,218,217,99,106,108,246,121 809,66,2153,121,164,811,1803,138,213,1422,156,99,36,918,246,2107,2785,144,25,79,611,330,217,730,218,179,89,1237,3391,6,40,2167,256,2389,2066,313,130,522,108,1553,45,381,78,2140,652,2032,1511,3135,106,24 0.3438753282799643,2.8070566341243905,-0.33156716576876,2.0442894948035293,1.7465774077703615,0.3438753282799643,-0.18826843715602568,1.9260244005596443,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,1.338473936006947,-0.30754673593761184,-0.6242916466860307,1.8863625663085712,4.1354813465701925,2.5638146678084146,0.5230949161824157,1.0232798624432902,1.4623099427802935,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,0.06950099771551356,-1.9788713010588765,5.121449989369716,3.370732425976295,-0.33156716576876,1.296917258531428,-0.42821167915506675,-0.28358176189719153,1.0869803140135814,1.9852909461843653,0.6556730905320322,2.1809317216381077,-0.07032759590587762,3.2093487244594585,0.937812905361756,2.5826783205648556,-0.30754673593761184,0.5008477318133796,-0.25967184066824295,-0.04689579872958434,-0.849577203134417,2.2197146760906703,4.186254663337337 3430
Hydrolase activity acting on glycosyl bonds 12 30 3.242201127745301 0.0011861028289441 Q9BTY2,O00754,O60476,P06865,P54802,O75503,P10253,O60502,P16278,P04062,P17900,P06280 Functions GO Molecular function msigdb_gomf 128,66,196,99,40,138,144,241,179,213,89,156 66,2260,196,241,138,213,1422,156,99,918,246,144,2375,2637,179,89,1934,2531,1389,40,1662,2499,1874,1304,3167,2960,381,128,780,2770 2.8070566341243905,-0.3797760297676727,1.5849251978248329,1.359199686384635,1.9260244005596443,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,1.338473936006947,1.8863625663085712,-0.42821167915506675,-0.5503155785430718,1.6457867663301875,2.431035510324411,-0.23581657417804916,-0.5012978577516536,-0.00018569005958125493,3.370732425976295,-0.11734646334023954,-0.4768775233718424,-0.2120155691768394,0.04632210615831087,-0.900350577456945,-0.7237852836123975,0.937812905361756,2.0049867171526095,0.38894919874105743,-0.5995724062727221 3430
Sphingolipid metabolism 13 26 3.182906844135887 0.0014580451609085 P17900,P06865,P07602,Q96G23,P27544,O95470,P16278,P04062,Q13510,P10619,Q06136,P06280,P51648 Processes and pathways Reactome Pathways msigdb_reactome 89,99,36,68,82,147,179,213,313,25,59,156,223 1632,548,1633,811,1638,147,213,156,99,36,918,25,730,179,89,1649,82,223,59,313,68,381,3003,1278,652,1973 -0.11734646334023954,0.6116509767559337,-0.11734646334023954,0.3438753282799643,-0.11734646334023954,1.866485968870282,1.4828295622266432,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,0.4114181815276483,1.6457867663301875,2.431035510324411,-0.11734646334023954,2.54492504446314,1.4417564181063023,2.8625913164326255,1.0869803140135814,2.7884960733515816,0.937812905361756,-0.7488153183487716,0.06950099771551356,0.5008477318133796,-0.23581657417804916 3430
Membrane lipid metabolic process 14 37 3.161726076968823 0.0015683702141224 P17900,P06865,P07602,Q96G23,P50897,Q8NCC3,P27544,O95470,O60512,P16278,P04062,Q13510,Q06136,P06280 Processes and pathways GO Biological process msigdb_gobp 89,99,36,68,6,108,82,147,150,179,213,313,59,156 548,1633,502,150,1805,147,213,1422,156,99,36,918,179,89,1649,82,532,6,1824,59,617,313,1305,3124,108,1007,1962,68,2965,381,2849,1620,1278,2972,652,1688,1973 0.6116509767559337,-0.11734646334023954,0.6776210718932071,1.8465787199040886,-0.18826843715602568,1.866485968870282,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,1.6457867663301875,2.431035510324411,-0.11734646334023954,2.54492504446314,0.6336831437767028,5.121449989369716,-0.18826843715602568,2.8625913164326255,0.5230949161824157,1.0869803140135814,0.04632210615831087,-0.849577203134417,2.1809317216381077,0.20754527371745304,-0.23581657417804916,2.7884960733515816,-0.7237852836123975,0.937812905361756,-0.6490720698046804,-0.09381103021537567,0.06950099771551356,-0.7237852836123975,0.5008477318133796,-0.11734646334023954,-0.23581657417804916 3430
Hydrolase activity hydrolyzing o glycosyl compounds 11 23 2.9558521092071333 0.0031180656211451 Q9BTY2,O00754,O60476,P06865,P54802,P10253,O60502,P16278,P04062,P17900,P06280 Functions GO Molecular function msigdb_gomf 128,66,196,99,40,144,241,179,213,89,156 66,196,241,213,1422,156,99,918,246,144,179,89,1389,40,1662,2499,1874,1304,2960,381,128,780,2770 2.8070566341243905,1.5849251978248329,1.359199686384635,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,1.338473936006947,1.8863625663085712,1.6457867663301875,2.431035510324411,-0.00018569005958125493,3.370732425976295,-0.11734646334023954,-0.4768775233718424,-0.2120155691768394,0.04632210615831087,-0.7237852836123975,0.937812905361756,2.0049867171526095,0.38894919874105743,-0.5995724062727221 3430
Receptor 13 42 2.9510170250608 0.0031672945832081 Q14108,P35613,O15118,Q8WTV0,P11717,P24390,Q99523,Q99720,O00264,Q14739,Q9NS69,O43731,P55899 Functions Protein Atlas Molecular function protein_atlas_molecular_function 130,254,164,71,330,13,78,47,239,50,23,123,287 239,1232,2203,164,344,123,728,856,1643,1807,1701,2479,1702,1023,611,330,1064,2267,1237,1107,13,504,254,287,1998,1435,681,130,50,1121,71,1789,544,78,874,47,906,23,3078,1912,584,833 1.359199686384635,0.06950099771551356,-0.35564345936189407,1.7465774077703615,0.9806232501634713,2.0246528531620718,0.4114181815276483,0.2986183093020084,-0.11734646334023954,-0.18826843715602568,-0.1409342612489813,-0.4768775233718424,-0.1409342612489813,0.18465877239643577,0.5230949161824157,1.0232798624432902,0.16172434863187643,-0.3797760297676727,0.06950099771551356,0.1387416835614649,4.7179169525566556,0.6776210718932071,1.296917258531428,1.1924031585962547,-0.25967184066824295,-0.02351528122041195,0.45622167162433763,1.9852909461843653,3.1189087835415297,0.1387416835614649,2.6953211040640213,-0.16457479426822091,0.6336831437767028,2.5826783205648556,0.2986183093020084,3.173240775887535,0.2759203789757193,4.236863344428605,-0.7990668710929513,-0.2120155691768394,0.567458949308088,0.3438753282799643 3430
Mitochondrial respiratory chain complex assembly 15 39 2.9366030717117795 0.0033182852773987 Q15070,O43676,Q96CU9,Q9BSK2,Q9Y6M9,P51970,P03886,Q9H061,Q9Y2R0,Q9P0J0,O43819,O75306,P47985,Q69YU5,Q6DKK2 Processes and pathways GO Biological process msigdb_gobp 350,35,103,136,373,425,15,16,81,211,360,309,439,30,31 698,35,2775,360,2104,309,1187,1920,752,753,1579,1930,610,15,2736,439,425,1394,350,1950,1537,30,31,1167,474,898,2182,103,136,2891,16,1509,3190,721,211,2197,81,546,373 0.4338422448747199,3.512707326927762,-0.6242916466860307,0.9592374039290533,-0.30754673593761184,1.0869803140135814,0.09263033605246422,-0.23581657417804916,0.38894919874105743,0.38894919874105743,-0.09381103021537567,-0.23581657417804916,0.5230949161824157,4.652417670407559,-0.5995724062727221,0.8084416390325024,0.8301027868261046,-0.00018569005958125493,0.9806232501634713,-0.23581657417804916,-0.07032759590587762,3.861838008707718,3.7926560390546924,0.1157104547340278,0.7432157338415764,0.2759203789757193,-0.33156716576876,2.239063866307495,1.965565398534416,-0.6739141572295496,4.5040637689029275,-0.04689579872958434,-0.9258372702304992,0.4338422448747199,1.5033154527373318,-0.33156716576876,2.5638146678084146,0.6336831437767028,0.9592374039290533 3430
Mitochondrial protein import 12 36 2.88351224641004 0.0039326735534057 Q9Y584,Q9Y5J9,O60830,P21796,Q5JRX3,O43615,O94826,Q9Y5L4,Q9NS69,O14925,Q99595,Q8N4H5 Processes and pathways Reactome Pathways msigdb_reactome 96,225,97,3,126,134,233,183,23,122,157,95 122,134,97,3231,1335,1578,699,233,2678,491,1290,3085,631,885,3,3111,2643,2164,1157,596,820,1538,126,95,157,3040,1412,23,298,977,2197,546,96,421,225,183 2.0442894948035293,1.965565398534416,2.3161817108012213,-1.0284638912585382,0.02309332399172761,-0.09381103021537567,0.4338422448747199,1.400546940102355,-0.5749138732638202,0.6995273401513898,0.04632210615831087,-0.8242894260138783,0.5008477318133796,0.2759203789757193,5.4060543445312685,-0.849577203134417,-0.5503155785430718,-0.33156716576876,0.1157104547340278,0.5452985658990057,0.3438753282799643,-0.07032759590587762,2.0049867171526095,2.35457505060863,1.8066716660719826,-0.7739090091989397,-0.00018569005958125493,4.236863344428605,1.1503444701717498,0.23038416792428346,-0.33156716576876,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875 3430
Exopeptidase activity 11 32 2.879119380452451 0.0039878734588845 Q9H3G5,P42785,Q9NZ08,O75844,Q9UIQ6,Q969V3,O75976,Q9HB40,P55786,O14773,P10619 Functions GO Molecular function msigdb_gomf 98,38,299,139,12,172,142,17,152,121,25 121,139,142,728,311,25,2324,3143,2582,1068,38,3322,152,3330,1437,793,845,1889,580,172,2847,1320,3171,98,2303,17,3045,3187,2716,299,12,1628 2.0442894948035293,1.9260244005596443,1.906208661011561,0.4114181815276483,1.0869803140135814,4.1354813465701925,-0.4039652952055236,-0.8749307389569164,-0.5257770590663371,0.16172434863187643,3.441890793303961,-1.2371040916101648,1.826640669391119,-1.263513845201833,-0.02351528122041195,0.36643501064183787,0.32126985958171844,-0.2120155691768394,0.567458949308088,1.7063569746264826,-0.6490720698046804,0.04632210615831087,-0.900350577456945,2.3161817108012213,-0.3797760297676727,4.454305506671291,-0.7739090091989397,-0.9258372702304992,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567 3430
Glycosidase 11 19 2.852390688437476 0.0043391733489941 Q9BTY2,O00754,O60476,P06865,P54802,P10253,O60502,P08236,P16278,P04062,P06280 Functions Protein Atlas Molecular function protein_atlas_molecular_function 128,66,196,99,40,144,241,246,179,213,156 66,2260,196,241,213,1422,156,99,918,246,144,179,1389,40,2499,1874,1304,381,128 2.8070566341243905,-0.3797760297676727,1.5849251978248329,1.359199686384635,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,1.338473936006947,1.8863625663085712,1.6457867663301875,-0.00018569005958125493,3.370732425976295,-0.4768775233718424,-0.2120155691768394,0.04632210615831087,0.937812905361756,2.0049867171526095 3430
Lytic vacuole organization 8 24 2.8087076200398 0.0049740797844377 Q14108,Q8N511,P50897,P54802,O75503,P10253,P11117,O14773 Processes and pathways GO Biological process msigdb_gobp 130,67,6,40,138,144,79,121 809,121,138,1754,213,918,144,79,482,6,2057,40,2540,1158,130,665,1078,67,1732,2888,3127,2358,1178,1627 0.3438753282799643,2.0442894948035293,1.9260244005596443,-0.16457479426822091,1.4828295622266432,0.25317576686812393,1.8863625663085712,2.5638146678084146,0.7213921450541884,5.121449989369716,-0.28358176189719153,3.370732425976295,-0.5012978577516536,0.1157104547340278,1.9852909461843653,0.4785567416325205,0.16172434863187643,2.8070566341243905,-0.1409342612489813,-0.6739141572295496,-0.849577203134417,-0.4039652952055236,0.1157104547340278,-0.09381103021537567 3430
Serine hydrolase activity 7 18 2.803145337159502 0.0050606858365604 Q16740,Q9H3G5,P42785,Q9HB40,O14773,P10619,Q5JRX3 Functions GO Molecular function msigdb_gomf 2,98,38,17,121,25,126 121,142,25,2480,2582,814,38,1482,635,704,2,868,1883,126,2505,845,98,17 2.0442894948035293,1.906208661011561,4.1354813465701925,-0.4768775233718424,-0.5257770590663371,0.3438753282799643,3.441890793303961,-0.04689579872958434,0.5008477318133796,0.4338422448747199,5.946267218904173,0.2986183093020084,-0.2120155691768394,2.0049867171526095,-0.4768775233718424,0.32126985958171844,2.3161817108012213,4.454305506671291 3430
Glycoside hydrolase superfamily [IPR017853] 8 16 2.800781471530484 0.005097902787176 Q9BTY2,P06865,P54802,P10253,O60502,P04062,P16278,P06280 Sequence InterPro Superfamily interpro_homologous_superfamily 128,99,40,144,241,213,179,156 241,213,1422,156,99,918,1988,246,144,179,1389,40,1662,1874,128,804 1.359199686384635,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,-0.25967184066824295,1.338473936006947,1.8863625663085712,1.6457867663301875,-0.00018569005958125493,3.370732425976295,-0.11734646334023954,-0.2120155691768394,2.0049867171526095,0.36643501064183787 3430
Glycosaminoglycan metabolism 10 15 2.798418287982107 0.0051353561104601 P06865,P54802,Q7LGA3,O43505,P08236,O60512,P16278,Q96L58,Q8TB61,P15586 Processes and pathways Reactome Pathways msigdb_reactome 99,40,171,146,246,150,179,215,92,218 261,146,150,787,99,918,246,218,179,40,171,92,215,2421,1465 1.2760859545124026,1.866485968870282,1.8465787199040886,0.36643501064183787,2.277678317409277,0.25317576686812393,1.338473936006947,1.4623099427802935,1.6457867663301875,3.370732425976295,1.7063569746264826,2.4119608690616183,1.4828295622266432,-0.42821167915506675,-0.02351528122041195 3430
Disproportionate short stature 15 30 2.77775675705662 0.0054735576362814 Q96MF7,Q15392,Q96HY6,P42345,Q9UHX1,Q7LGA3,Q9UBN7,O95613,Q14739,O75718,Q32P28,P16278,Q6DKJ4,P10644,Q9UBM7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,34,294,482,8,171,500,516,50,361,247,179,117,589,154 1183,606,3218,952,2630,361,516,589,179,3244,482,1864,1118,1664,1828,50,2957,34,247,117,171,2297,2610,294,290,1909,154,500,8,1467 0.09263033605246422,0.5230949161824157,-1.0027041076562464,0.23038416792428346,-0.5503155785430718,0.9592374039290533,0.6556730905320322,0.5452985658990057,1.6457867663301875,-1.0542934068429035,0.7213921450541884,-0.2120155691768394,0.1387416835614649,-0.11734646334023954,-0.18826843715602568,3.1189087835415297,-0.7237852836123975,3.583187167896173,1.338473936006947,2.083474851760708,1.7063569746264826,-0.3797760297676727,-0.5257770590663371,1.171392087430195,1.1924031585962547,-0.2120155691768394,1.826640669391119,0.6995273401513898,5.057543677692156,-0.02351528122041195 3430
Predicted secreted proteins 22 53 2.767373109829556 0.0056510039312283 Q9BTY2,Q15165,P61916,P80303,P43490,Q9HB40,Q08431,Q9H9S5,Q9Y287,Q9NZ08,P17931,P05067,Q9UM22,Q8WUJ1,Q9UMX5,P04083,Q08380,P09429,O75718,O00584,Q02818,O94919 Functions Protein Atlas Protein class protein_atlas_protein_class 128,1,256,9,11,17,404,283,166,299,301,46,53,76,77,83,93,363,361,249,125,374 249,1232,550,2477,361,660,374,728,83,46,1758,2105,2864,363,2635,1064,1989,2267,301,3244,2982,1994,11,1865,2058,256,1998,9,125,841,93,404,2282,1252,1,793,3386,1551,76,417,1318,601,2853,128,2661,2303,283,17,299,53,77,166,657 1.3177131892594451,0.06950099771551356,0.6116509767559337,-0.4768775233718424,0.9592374039290533,0.4785567416325205,0.937812905361756,0.4114181815276483,2.5260093370892096,3.191306028311356,-0.16457479426822091,-0.30754673593761184,-0.6739141572295496,0.9592374039290533,-0.5503155785430718,0.16172434863187643,-0.25967184066824295,-0.3797760297676727,1.1292601049826305,-1.0542934068429035,-0.7488153183487716,-0.25967184066824295,4.864332563034109,-0.2120155691768394,-0.28358176189719153,1.296917258531428,-0.25967184066824295,4.993390704618005,2.0246528531620718,0.32126985958171844,2.3737307600439475,0.8733052663722602,-0.3797760297676727,0.06950099771551356,6.5440889483340765,0.36643501064183787,-1.8649399009731702,-0.07032759590587762,2.601516115344004,0.8517239183017473,0.04632210615831087,0.5452985658990057,-0.6490720698046804,2.0049867171526095,-0.5503155785430718,-0.3797760297676727,1.213377883648462,4.454305506671291,1.1503444701717498,3.0643705285634333,2.601516115344004,1.7465774077703615,0.5008477318133796 3430
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 10 34 2.7582065828261446 0.0058119455625749 O15460,Q16850,Q8NB78,P13674,P16435,P30519,Q15800,Q6UW02,P09601,Q32P28 Functions GO Molecular function msigdb_gomf 434,351,135,395,519,14,178,338,20,247 2624,1574,434,2976,550,1061,1188,1421,2373,1337,20,395,519,1193,14,1819,1533,2000,734,178,351,247,1723,1667,338,1833,2403,1261,1550,135,1457,1410,1565,2363 -0.5503155785430718,-0.09381103021537567,0.8084416390325024,-0.7488153183487716,0.6116509767559337,0.16172434863187643,0.09263033605246422,-0.02351528122041195,-0.42821167915506675,0.02309332399172761,4.337593478683959,0.8948470616767685,0.6556730905320322,0.09263033605246422,4.701566951120029,-0.18826843715602568,-0.07032759590587762,-0.25967184066824295,0.4114181815276483,1.6660089911781828,0.9806232501634713,1.338473936006947,-0.1409342612489813,-0.11734646334023954,1.0019706637911983,-0.18826843715602568,-0.42821167915506675,0.06950099771551356,-0.07032759590587762,1.965565398534416,-0.02351528122041195,-0.00018569005958125493,-0.07032759590587762,-0.4039652952055236 3430
Tetrapyrrole binding 10 18 2.749625861536481 0.0059663344746667 Q16850,Q8WUJ1,Q9H7Z7,O00264,P30519,Q6UW02,P09601,O43169,P53701,Q9Y5Z4 Functions GO Molecular function msigdb_gomf 351,76,143,239,14,338,20,55,276,322 239,344,55,1290,20,2212,14,276,351,338,968,76,1213,1456,143,2766,2368,322 1.359199686384635,0.9806232501634713,2.9546651894343055,0.04632210615831087,4.337593478683959,-0.35564345936189407,4.701566951120029,1.2343164607296082,0.9806232501634713,1.0019706637911983,0.23038416792428346,2.601516115344004,0.09263033605246422,-0.02351528122041195,1.906208661011561,-0.5995724062727221,-0.4039652952055236,1.0657844750365362 3430
Vacuolar lumen 30 66 2.6935654271097764 0.0070692269306067 Q9BTY2,Q14108,P61916,P50897,Q9H7Z7,P10253,P38435,P10619,P06280,P07602,P54802,O00560,Q8NHP8,Q8IV08,P16278,Q9UM22,Q13510,Q9Y5Z4,O00754,P46976,P11117,P04062,P17900,Q9BRF8,P15586,P13473,P06865,O00584,P08236,O14773 Localization GO Cellular component msigdb_gocc 128,130,256,6,143,144,145,25,156,36,40,300,44,175,179,53,313,322,66,331,79,213,89,357,218,217,99,249,246,121 300,249,66,121,811,2901,213,1422,156,99,2105,2106,36,918,661,246,144,25,79,1584,2159,217,730,218,179,89,1650,2870,145,3391,331,1940,6,3162,2382,2328,40,2166,2694,256,2589,1434,2915,2448,1824,618,313,130,1776,175,2134,44,580,1500,2022,381,1793,357,128,804,143,3258,652,53,2362,322 1.1292601049826305,1.3177131892594451,2.8070566341243905,2.0442894948035293,0.3438753282799643,-0.6988183969795223,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,-0.30754673593761184,-0.30754673593761184,3.495034957042614,0.25317576686812393,0.4785567416325205,1.338473936006947,1.8863625663085712,4.1354813465701925,2.5638146678084146,-0.09381103021537567,-0.33156716576876,1.4623099427802935,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,-0.11734646334023954,-0.6739141572295496,1.8863625663085712,-1.9788713010588765,1.0232798624432902,-0.23581657417804916,5.121449989369716,-0.900350577456945,-0.42821167915506675,-0.4039652952055236,3.370732425976295,-0.33156716576876,-0.5749138732638202,1.296917258531428,-0.5257770590663371,-0.02351528122041195,-0.6988183969795223,-0.4525156104496164,-0.18826843715602568,0.5230949161824157,1.0869803140135814,1.9852909461843653,-0.16457479426822091,1.6861990067024655,-0.30754673593761184,3.281295714487462,0.567458949308088,-0.04689579872958434,-0.25967184066824295,0.937812905361756,-0.16457479426822091,0.9806232501634713,2.0049867171526095,0.36643501064183787,1.906208661011561,-1.0542934068429035,0.5008477318133796,3.0643705285634333,-0.4039652952055236,1.0657844750365362 3430
Respiratory chain 13 33 2.6705157576461955 0.0075734816722972 O43676,Q96CU9,Q9Y6M9,O14949,P51970,P00403,P03886,Q9P0J0,O75306,P22695,P47985,Q9UDW1,Q6DKK2 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 35,103,373,243,425,394,15,211,309,274,439,284,31 698,2257,243,35,2775,2104,309,1697,1187,1920,753,2780,1579,610,394,15,1290,3204,2578,274,2736,2688,439,3196,425,1950,1537,31,474,103,211,284,373 0.4338422448747199,-0.3797760297676727,1.338473936006947,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.977013463993979,-0.5257770590663371,1.2343164607296082,-0.5995724062727221,-0.5749138732638202,0.8084416390325024,-0.9513913766449668,0.8301027868261046,-0.23581657417804916,-0.07032759590587762,3.7926560390546924,0.7432157338415764,2.239063866307495,1.5033154527373318,1.213377883648462,0.9592374039290533 3430
Ceramide metabolic process 10 18 2.6617147749310397 0.0077743725212386 P17900,P06865,Q96G23,Q8NCC3,P27544,O95470,P04062,O60512,Q13510,P06280 Processes and pathways GO Biological process msigdb_gobp 89,99,68,108,82,147,213,150,313,156 548,1633,150,147,213,156,99,918,89,82,532,1824,313,1305,108,68,381,1278 0.6116509767559337,-0.11734646334023954,1.8465787199040886,1.866485968870282,1.4828295622266432,1.8066716660719826,2.277678317409277,0.25317576686812393,2.431035510324411,2.54492504446314,0.6336831437767028,-0.18826843715602568,1.0869803140135814,0.04632210615831087,2.1809317216381077,2.7884960733515816,0.937812905361756,0.06950099771551356 3430
Metalloprotease 9 27 2.616393334433213 0.0088864124323295 Q99797,Q9NZ08,O75844,Q9UIQ6,O75976,P42892,O95630,P55786,Q5JRX3 Functions Protein Atlas Molecular function protein_atlas_molecular_function 199,299,139,12,142,49,245,152,126 2625,951,1578,139,142,245,311,2324,2267,49,2220,152,126,793,543,1320,1008,199,1175,2303,3045,3187,2716,299,12,1628,948 -0.5503155785430718,0.23038416792428346,-0.09381103021537567,1.9260244005596443,1.906208661011561,1.338473936006947,1.0869803140135814,-0.4039652952055236,-0.3797760297676727,3.1189087835415297,-0.35564345936189407,1.826640669391119,2.0049867171526095,0.36643501064183787,0.6336831437767028,0.04632210615831087,0.20754527371745304,1.5849251978248329,0.1157104547340278,-0.3797760297676727,-0.7739090091989397,-0.9258372702304992,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567,0.25317576686812393 3430
Aminoglycan metabolic process 7 15 2.6046926268628376 0.0091956714238154 P06865,P54802,Q7LGA3,O43505,P16278,Q96L58,P15586 Processes and pathways GO Biological process msigdb_gobp 99,40,171,146,179,215,218 146,1983,1581,1422,99,918,246,218,179,40,2389,2595,171,215,1465 1.866485968870282,-0.25967184066824295,-0.09381103021537567,-0.02351528122041195,2.277678317409277,0.25317576686812393,1.338473936006947,1.4623099427802935,1.6457867663301875,3.370732425976295,-0.42821167915506675,-0.5257770590663371,1.7063569746264826,1.4828295622266432,-0.02351528122041195 3430
metalloprotease 8 27 2.590592050364623 0.009581099408509 Q99797,O75844,Q9UIQ6,P42892,O95630,P22695,P55786,Q5JRX3 Functions Panther Protein class panther_protein_class 199,139,12,49,245,274,152,126 951,1578,139,245,728,2324,2267,274,3143,2688,49,2220,152,1157,126,793,1889,1320,1008,199,1175,3045,2716,299,12,1628,948 0.23038416792428346,-0.09381103021537567,1.9260244005596443,1.338473936006947,0.4114181815276483,-0.4039652952055236,-0.3797760297676727,1.2343164607296082,-0.8749307389569164,-0.5749138732638202,3.1189087835415297,-0.35564345936189407,1.826640669391119,0.1157104547340278,2.0049867171526095,0.36643501064183787,-0.2120155691768394,0.04632210615831087,0.20754527371745304,1.5849251978248329,0.1157104547340278,-0.7739090091989397,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567,0.25317576686812393 3430
Biliary tract abnormality 9 29 2.590273720961474 0.0095899645252617 O96028,Q14108,P07602,Q96J02,Q14739,O15078,P09601,P04062,Q9UJW0 Drugs and Diseases Human Phenotype Ontology msigdb_hp 191,130,36,295,50,304,20,213,321 304,811,383,191,954,213,36,20,1989,730,3295,814,1113,1817,1941,1157,1713,2797,130,50,896,1554,295,2145,652,1909,321,2197,3048 1.1081387881403877,0.3438753282799643,0.9163495326117879,1.6052450348577447,0.23038416792428346,1.4828295622266432,3.495034957042614,4.337593478683959,-0.25967184066824295,0.4114181815276483,-1.15832093411627,0.3438753282799643,0.1387416835614649,-0.18826843715602568,-0.23581657417804916,0.1157104547340278,-0.1409342612489813,-0.6242916466860307,1.9852909461843653,3.1189087835415297,0.2759203789757193,-0.07032759590587762,1.171392087430195,-0.30754673593761184,0.5008477318133796,-0.2120155691768394,1.0657844750365362,-0.33156716576876,-0.7739090091989397 3430
Anion transmembrane transport 23 40 2.565155946646939 0.0103129442319576 P21796,P12235,P51798,Q9H2D1,P45880,Q9UHG3,Q96NB2,Q9Y6M7,Q9Y619,Q4KMQ2,Q9UBX3,P08183,O75746,Q13546,Q8TB61,Q9BQT8,Q14728,P05556,Q8IWT6,P55011,Q9BXP2,Q9Y277,P30825 Processes and pathways GO Biological process msigdb_gobp 3,631,520,151,26,27,827,835,57,821,189,323,699,706,92,486,866,856,773,495,903,911,504 1855,2935,699,1985,1520,2049,856,323,1988,631,885,3,504,26,520,2381,1657,495,1350,1247,706,866,964,1121,821,773,92,827,486,903,151,1903,1326,189,27,977,911,2722,57,835 -0.2120155691768394,-0.7237852836123975,0.4338422448747199,-0.25967184066824295,-0.07032759590587762,-0.28358176189719153,0.2986183093020084,1.0445510616836513,-0.25967184066824295,0.5008477318133796,0.2759203789757193,5.4060543445312685,0.6776210718932071,4.1354813465701925,0.6556730905320322,-0.42821167915506675,-0.11734646334023954,0.6995273401513898,0.02309332399172761,0.06950099771551356,0.4338422448747199,0.2986183093020084,0.23038416792428346,0.1387416835614649,0.3438753282799643,0.38894919874105743,2.4119608690616183,0.3438753282799643,0.7213921450541884,0.2759203789757193,1.8465787199040886,-0.2120155691768394,0.04632210615831087,1.6255321690560474,4.118520027903667,0.23038416792428346,0.2759203789757193,-0.5749138732638202,2.8994929547828066,0.3438753282799643 3430
Nadh dehydrogenase complex assembly 9 28 2.53385847637828 0.0112814284051592 Q15070,O43676,Q96CU9,Q9Y6M9,P51970,P03886,Q9H061,Q9P0J0,O75306 Processes and pathways GO Biological process msigdb_gobp 350,35,103,373,425,15,16,211,309 698,35,2775,2104,309,1187,1920,753,1579,610,15,2736,425,350,1950,1537,1167,474,898,2182,103,2891,16,1509,721,211,2197,373 0.4338422448747199,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.09381103021537567,0.5230949161824157,4.652417670407559,-0.5995724062727221,0.8301027868261046,0.9806232501634713,-0.23581657417804916,-0.07032759590587762,0.1157104547340278,0.7432157338415764,0.2759203789757193,-0.33156716576876,2.239063866307495,-0.6739141572295496,4.5040637689029275,-0.04689579872958434,0.4338422448747199,1.5033154527373318,-0.33156716576876,0.9592374039290533 3430
Signal sequence binding 9 29 2.525727896177107 0.0115458868957409 Q9Y584,P52294,O00505,O00629,O94826,P24390,O60684,Q92973,O43731 Functions GO Molecular function msigdb_gomf 96,255,226,195,233,13,110,182,123 1019,226,195,586,123,110,233,13,1427,2690,577,2443,1817,305,255,635,3116,2834,2223,1778,3097,820,1005,182,1676,2413,945,696,96 0.18465877239643577,1.4211688103555455,1.5849251978248329,0.5452985658990057,2.0246528531620718,2.122543890584666,1.400546940102355,4.7179169525566556,-0.02351528122041195,-0.5749138732638202,0.567458949308088,-0.4525156104496164,-0.18826843715602568,1.1081387881403877,1.296917258531428,0.5008477318133796,-0.849577203134417,-0.6490720698046804,-0.35564345936189407,-0.16457479426822091,-0.8242894260138783,0.3438753282799643,0.20754527371745304,1.6457867663301875,-0.11734646334023954,-0.42821167915506675,0.25317576686812393,0.45622167162433763,2.3353920752424693 3430
Protein insertion into membrane 15 29 2.521573830707524 0.0116831155346937 Q15629,P46379,Q9Y584,Q15070,Q9Y5J9,O43765,O14737,O94826,Q9Y512,Q9Y5L4,Q9P0J0,Q9NS69,Q9Y5J7,P07900,Q07812 Processes and pathways GO Biological process msigdb_gobp 64,161,96,350,225,627,70,233,546,183,211,23,421,661,617 70,811,627,233,661,2687,2944,161,2834,617,1488,350,64,1305,2804,1311,1959,1083,717,1327,23,3259,211,2197,546,96,421,225,183 2.6953211040640213,0.3438753282799643,0.5008477318133796,1.400546940102355,0.4785567416325205,-0.5749138732638202,-0.7237852836123975,1.7666401896879766,-0.6490720698046804,0.5230949161824157,-0.04689579872958434,0.9806232501634713,2.825592626630927,0.04632210615831087,-0.6242916466860307,0.04632210615831087,-0.23581657417804916,0.16172434863187643,0.4338422448747199,0.04632210615831087,4.236863344428605,-1.0542934068429035,1.5033154527373318,-0.33156716576876,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875 3430
Sensorimotor neuropathy 11 30 2.5148575231487658 0.0119080496190759 Q15120,P07602,P40939,Q13217,Q9NSE4,Q92734,P00403,P03886,Q9Y2R0,Q9NR77,O60313 Drugs and Diseases Human Phenotype Ontology msigdb_hp 415,36,386,618,400,523,394,15,81,60,94 915,1633,94,1930,394,15,1423,1106,36,837,2981,1425,386,2444,1941,2166,2646,1870,618,415,932,523,2754,802,60,400,2030,652,81,948 0.25317576686812393,-0.11734646334023954,2.35457505060863,-0.23581657417804916,0.8948470616767685,4.652417670407559,-0.02351528122041195,0.1387416835614649,3.495034957042614,0.32126985958171844,-0.7488153183487716,-0.02351528122041195,0.9163495326117879,-0.4525156104496164,-0.23581657417804916,-0.33156716576876,-0.5503155785430718,-0.2120155691768394,0.5230949161824157,0.8517239183017473,0.25317576686812393,0.6556730905320322,-0.5995724062727221,0.36643501064183787,2.8625913164326255,0.8948470616767685,-0.25967184066824295,0.5008477318133796,2.5638146678084146,0.25317576686812393 3430
Sphingolipid biosynthetic process 6 15 2.514582377505292 0.0119173457754346 Q96G23,P27544,O95470,P04062,O60512,Q06136 Processes and pathways GO Biological process msigdb_gobp 68,82,147,213,150,59 548,1633,150,147,213,1649,82,1824,59,313,1305,68,1278,1688,1973 0.6116509767559337,-0.11734646334023954,1.8465787199040886,1.866485968870282,1.4828295622266432,-0.11734646334023954,2.54492504446314,-0.18826843715602568,2.8625913164326255,1.0869803140135814,0.04632210615831087,2.7884960733515816,0.06950099771551356,-0.11734646334023954,-0.23581657417804916 3430
Protein targeting to mitochondrion 16 46 2.505275348213438 0.0122356098808262 Q9Y584,Q9Y5J9,O60830,Q5JRX3,O43615,Q99797,O14737,O14925,O94826,Q9P0J0,Q9Y5L4,Q9NS69,P55786,Q9UII2,Q99595,Q8N4H5 Processes and pathways GO Biological process msigdb_gobp 96,225,97,126,134,199,70,122,233,211,183,23,152,222,157,95 2773,70,122,134,97,1578,233,2631,1289,1700,1930,2678,661,3085,3142,1194,2944,263,2792,2380,152,2914,1157,820,2802,1538,1305,126,1607,95,368,559,157,199,649,1412,23,211,3290,222,3284,546,96,421,225,183 -0.6242916466860307,2.6953211040640213,2.0442894948035293,1.965565398534416,2.3161817108012213,-0.09381103021537567,1.400546940102355,-0.5503155785430718,0.04632210615831087,-0.1409342612489813,-0.23581657417804916,-0.5749138732638202,0.4785567416325205,-0.8242894260138783,-0.8749307389569164,0.09263033605246422,-0.7237852836123975,1.2760859545124026,-0.6242916466860307,-0.42821167915506675,1.826640669391119,-0.6988183969795223,0.1157104547340278,0.3438753282799643,-0.6242916466860307,-0.07032759590587762,0.04632210615831087,2.0049867171526095,-0.09381103021537567,2.35457505060863,0.9592374039290533,0.6116509767559337,1.8066716660719826,1.5849251978248329,0.5008477318133796,-0.00018569005958125493,4.236863344428605,1.5033154527373318,-1.1322063957742325,1.4623099427802935,-1.1061640452367623,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875 3430
Molecular transducer activity 7 34 2.492482508520628 0.0126853578482826 Q15629,Q14108,O15118,Q8WTV0,P11717,Q99523,Q99720 Functions GO Molecular function msigdb_gomf 64,130,164,71,330,78,47 1232,2203,164,344,856,1807,1023,330,1237,1194,2113,3207,1653,1245,1435,681,130,64,1121,1122,1723,71,1789,544,1216,78,47,3201,1414,3078,1052,653,1280,1571 0.06950099771551356,-0.35564345936189407,1.7465774077703615,0.9806232501634713,0.2986183093020084,-0.18826843715602568,0.18465877239643577,1.0232798624432902,0.06950099771551356,0.09263033605246422,-0.30754673593761184,-0.977013463993979,-0.11734646334023954,0.06950099771551356,-0.02351528122041195,0.45622167162433763,1.9852909461843653,2.825592626630927,0.1387416835614649,0.1387416835614649,-0.1409342612489813,2.6953211040640213,-0.16457479426822091,0.6336831437767028,0.09263033605246422,2.5826783205648556,3.173240775887535,-0.9513913766449668,-0.00018569005958125493,-0.7990668710929513,0.18465877239643577,0.5008477318133796,0.06950099771551356,-0.07032759590587762 3430
Steroid metabolism 11 28 2.487370390948344 0.012869133630913 Q16850,Q15392,P61916,O15118,O76062,Q06520,Q15800,Q14739,P54646,P04062,Q9UBM7 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 351,34,256,164,69,7,178,50,336,213,154 164,587,1421,69,1519,2901,213,1990,2213,857,385,3412,336,256,1868,2591,7,3347,50,3099,34,1880,178,351,2560,154,1800,1376 1.7465774077703615,0.5452985658990057,-0.02351528122041195,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,-0.25967184066824295,-0.35564345936189407,0.2986183093020084,0.9163495326117879,-2.360290770874015,1.0019706637911983,1.296917258531428,-0.2120155691768394,-0.5257770590663371,5.105496372209571,-1.3431986759033332,3.1189087835415297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,-0.5012978577516536,1.826640669391119,-0.16457479426822091,0.02309332399172761 3430
Membrane lipid catabolic process 7 13 2.462727636439284 0.0137884614113414 P17900,P06865,P50897,O95470,P04062,Q13510,P06280 Processes and pathways GO Biological process msigdb_gobp 89,99,6,147,213,313,156 147,213,1422,156,99,918,89,6,1824,313,381,2849,1278 1.866485968870282,1.4828295622266432,-0.02351528122041195,1.8066716660719826,2.277678317409277,0.25317576686812393,2.431035510324411,5.121449989369716,-0.18826843715602568,1.0869803140135814,0.937812905361756,-0.6490720698046804,0.06950099771551356 3430
Entry into host 8 34 2.450888055804404 0.0142504264212126 Q9BTY2,Q14108,O00505,P35613,Q96J02,O15118,Q8WTV0,P14373 Processes and pathways GO Biological process msigdb_gobp 128,130,226,254,295,164,71,251 2097,226,1232,164,3015,728,856,1643,1807,1337,1988,2479,1702,611,1064,251,2267,2271,1424,254,2053,2443,1998,1301,130,1718,1121,71,1789,295,740,128,1178,332 -0.30754673593761184,1.4211688103555455,0.06950099771551356,1.7465774077703615,-0.7739090091989397,0.4114181815276483,0.2986183093020084,-0.11734646334023954,-0.18826843715602568,0.02309332399172761,-0.25967184066824295,-0.4768775233718424,-0.1409342612489813,0.5230949161824157,0.16172434863187643,1.3177131892594451,-0.3797760297676727,-0.3797760297676727,-0.02351528122041195,1.296917258531428,-0.28358176189719153,-0.4525156104496164,-0.25967184066824295,0.04632210615831087,1.9852909461843653,-0.1409342612489813,0.1387416835614649,2.6953211040640213,-0.16457479426822091,1.171392087430195,0.4114181815276483,2.0049867171526095,0.1157104547340278,1.0232798624432902 3430
Hormone metabolic process 7 29 2.4381840499809653 0.0147612562363885 Q06520,O75844,Q9HB40,P42892,O95470,Q9UBM7,Q14849 Processes and pathways GO Biological process msigdb_gobp 7,139,17,49,147,154,62 1060,139,3417,147,1423,2267,2683,519,1194,234,49,3179,1941,2537,2281,7,62,2453,822,771,1728,2885,2076,2557,2560,17,154,1911,1914 0.16172434863187643,1.9260244005596443,-2.729289471050285,1.866485968870282,-0.02351528122041195,-0.3797760297676727,-0.5749138732638202,0.6556730905320322,0.09263033605246422,1.400546940102355,3.1189087835415297,-0.9258372702304992,-0.23581657417804916,-0.5012978577516536,-0.3797760297676727,5.105496372209571,2.8441041534478297,-0.4525156104496164,0.3438753282799643,0.38894919874105743,-0.1409342612489813,-0.6739141572295496,-0.28358176189719153,-0.5012978577516536,-0.5012978577516536,4.454305506671291,1.826640669391119,-0.2120155691768394,-0.2120155691768394 3430
Steroid binding 9 23 2.437052632237584 0.0148075239361344 Q14108,P21796,P61916,O15118,O00264,P38435,P04062,P45880,Q14849 Functions GO Molecular function msigdb_gomf 130,3,256,164,239,145,213,26,62 239,164,344,587,1519,213,1423,3018,3,1649,1704,1194,857,145,26,256,130,62,687,2355,2141,514,3377 1.359199686384635,1.7465774077703615,0.9806232501634713,0.5452985658990057,-0.07032759590587762,1.4828295622266432,-0.02351528122041195,-0.7739090091989397,5.4060543445312685,-0.11734646334023954,-0.1409342612489813,0.09263033605246422,0.2986183093020084,1.8863625663085712,4.1354813465701925,1.296917258531428,1.9852909461843653,2.8441041534478297,0.45622167162433763,-0.4039652952055236,-0.30754673593761184,0.6776210718932071,-1.6968271446485936 3430
Protein transporter activity 7 15 2.435564531142594 0.0148685722452472 Q9Y584,Q9Y5J9,O60830,Q9HD20,Q9NS69,O14925,Q99595 Functions GO Molecular function msigdb_gomf 96,225,97,105,23,122,157 122,97,233,2678,762,2834,1248,820,1890,157,105,23,653,96,225 2.0442894948035293,2.3161817108012213,1.400546940102355,-0.5749138732638202,0.38894919874105743,-0.6490720698046804,0.06950099771551356,0.3438753282799643,-0.2120155691768394,1.8066716660719826,2.2197146760906703,4.236863344428605,0.5008477318133796,2.3353920752424693,1.4417564181063023 3430
Negative regulation of rna catabolic process 14 32 2.410488287810004 0.0159311828252255 Q9Y2W1,O60506,P98175,Q9H2U1,Q99729,Q14011,P35637,P11940,P07910,O95453,Q14103,Q06787,Q92804,P67809 Processes and pathways GO Biological process msigdb_gobp 584,292,397,431,430,426,140,518,517,119,443,153,187,252 744,292,2861,1518,119,517,518,140,1863,252,397,2063,153,1825,1869,2917,2391,637,426,443,1440,1668,1961,187,1041,430,2759,1220,431,904,1687,584 0.38894919874105743,1.171392087430195,-0.6739141572295496,-0.07032759590587762,2.063896781548296,0.6556730905320322,0.6556730905320322,1.9260244005596443,-0.2120155691768394,1.3177131892594451,0.8948470616767685,-0.28358176189719153,1.826640669391119,-0.18826843715602568,-0.2120155691768394,-0.6988183969795223,-0.42821167915506675,0.5008477318133796,0.8301027868261046,0.8084416390325024,-0.02351528122041195,-0.11734646334023954,-0.23581657417804916,1.6255321690560474,0.18465877239643577,0.8301027868261046,-0.5995724062727221,0.09263033605246422,0.8301027868261046,0.2759203789757193,-0.11734646334023954,0.567458949308088 3430
Dysostosis multiplex 6 10 2.4096688996969835 0.0159670035713381 O00754,P54802,P08236,P16278,P10619,P15586 Drugs and Diseases Human Phenotype Ontology msigdb_hp 66,40,246,179,25,218 66,1422,246,25,218,179,40,1732,381,2770 2.8070566341243905,-0.02351528122041195,1.338473936006947,4.1354813465701925,1.4623099427802935,1.6457867663301875,3.370732425976295,-0.1409342612489813,0.937812905361756,-0.5995724062727221 3430
Secondary alcohol metabolic process 18 46 2.3960553203711763 0.016572588856196 Q16850,P48735,Q15392,P61916,O15118,O76062,Q06520,Q8WTV0,P05067,Q15800,Q9BQE5,Q14739,P54646,P04062,P48449,Q14849,Q9UBM7,O75874 Processes and pathways GO Biological process msigdb_gobp 351,129,34,256,164,69,7,71,46,178,19,50,336,213,112,62,154,286 164,1284,587,1421,286,69,1519,2901,213,46,3361,1990,519,2213,3384,857,385,2644,112,129,2114,3222,2164,2382,3412,336,2537,256,1868,2591,7,3347,734,50,62,3099,34,1880,178,351,71,3040,19,2141,154,1800 1.7465774077703615,0.04632210615831087,0.5452985658990057,-0.02351528122041195,1.1924031585962547,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,3.191306028311356,-1.4505344444969863,-0.25967184066824295,0.6556730905320322,-0.35564345936189407,-1.8366930943997668,0.2986183093020084,0.9163495326117879,-0.5503155785430718,2.122543890584666,1.9852909461843653,-0.30754673593761184,-1.0027041076562464,-0.33156716576876,-0.42821167915506675,-2.360290770874015,1.0019706637911983,-0.5012978577516536,1.296917258531428,-0.2120155691768394,-0.5257770590663371,5.105496372209571,-1.3431986759033332,0.4114181815276483,3.1189087835415297,2.8441041534478297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,2.6953211040640213,-0.7739090091989397,4.3877182006716735,-0.30754673593761184,1.826640669391119,-0.16457479426822091 3430
Abnormal biliary tract morphology 7 26 2.395608018835161 0.0165928243248119 Q14108,P07602,Q96J02,Q14739,O15078,P09601,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 130,36,295,50,304,20,213 304,811,954,213,36,20,1989,730,3295,814,1113,1817,1941,1157,1713,130,50,896,1554,295,2145,652,1909,321,2197,3048 1.1081387881403877,0.3438753282799643,0.23038416792428346,1.4828295622266432,3.495034957042614,4.337593478683959,-0.25967184066824295,0.4114181815276483,-1.15832093411627,0.3438753282799643,0.1387416835614649,-0.18826843715602568,-0.23581657417804916,0.1157104547340278,-0.1409342612489813,1.9852909461843653,3.1189087835415297,0.2759203789757193,-0.07032759590587762,1.171392087430195,-0.30754673593761184,0.5008477318133796,-0.2120155691768394,1.0657844750365362,-0.33156716576876,-0.7739090091989397 3430
Proportionate short stature 11 35 2.395357660651097 0.0166041597440644 Q96MF7,Q15392,Q96HY6,Q13535,Q16836,Q14739,P16278,Q96L58,P53701,Q9Y619,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,34,294,348,42,50,179,215,276,57,25 3218,2897,2630,25,589,179,2161,1763,2440,3245,2583,1862,1705,2643,386,994,634,276,840,537,348,2498,50,34,2341,42,2958,792,3170,1501,294,215,290,1323,57 -1.0027041076562464,-0.6988183969795223,-0.5503155785430718,4.1354813465701925,0.5452985658990057,1.6457867663301875,-0.33156716576876,-0.16457479426822091,-0.4525156104496164,-1.0542934068429035,-0.5257770590663371,-0.2120155691768394,-0.1409342612489813,-0.5503155785430718,0.9163495326117879,0.20754527371745304,0.5008477318133796,1.2343164607296082,0.32126985958171844,0.6336831437767028,0.9806232501634713,-0.4768775233718424,3.1189087835415297,3.583187167896173,-0.4039652952055236,3.3350234117032413,-0.7237852836123975,0.36643501064183787,-0.900350577456945,-0.04689579872958434,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,2.8994929547828066 3430
Glycosphingolipid metabolism 8 16 2.39292513340026 0.0167146513237748 P17900,P06865,P07602,P04062,P16278,Q13510,P10619,P06280 Processes and pathways Reactome Pathways msigdb_reactome 89,99,36,213,179,313,25,156 1632,811,213,156,99,36,918,25,730,179,89,313,381,3003,1278,652 -0.11734646334023954,0.3438753282799643,1.4828295622266432,1.8066716660719826,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,0.4114181815276483,1.6457867663301875,2.431035510324411,1.0869803140135814,0.937812905361756,-0.7488153183487716,0.06950099771551356,0.5008477318133796 3430
Cupped ear 6 13 2.3916125460421727 0.016774540119409 Q15392,P63241,Q01082,P78318,P42892,Q9P2D1 Drugs and Diseases Human Phenotype Ontology msigdb_hp 34,347,483,462,49,221 1473,1759,49,1431,347,462,483,1535,34,498,1607,1734,221 -0.04689579872958434,-0.16457479426822091,3.1189087835415297,-0.02351528122041195,0.9806232501634713,0.7649983512811526,0.7213921450541884,-0.07032759590587762,3.583187167896173,0.6995273401513898,-0.09381103021537567,-0.1409342612489813,1.4623099427802935 3430
Abnormal chorioretinal morphology 13 28 2.384204901448925 0.0171160693126715 O14936,Q9P2D1,P40939,P40855,Q01082,O60826,Q8NAT1,O43505,O15078,P04439,P53701,Q9Y619,Q9H9S5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 530,221,386,577,483,107,273,146,304,335,276,57,283 530,304,146,2101,107,2726,1921,1931,335,1340,1705,577,386,1817,634,276,483,921,1157,1158,896,3170,273,2607,1732,283,221,57 0.6336831437767028,1.1081387881403877,1.866485968870282,-0.30754673593761184,2.1809317216381077,-0.5995724062727221,-0.23581657417804916,-0.23581657417804916,1.0019706637911983,0.02309332399172761,-0.1409342612489813,0.567458949308088,0.9163495326117879,-0.18826843715602568,0.5008477318133796,1.2343164607296082,0.7213921450541884,0.25317576686812393,0.1157104547340278,0.1157104547340278,0.2759203789757193,-0.900350577456945,1.2552190861703458,-0.5257770590663371,-0.1409342612489813,1.213377883648462,1.4623099427802935,2.8994929547828066 3430
Calcium-binding protein 9 21 2.3791361846667867 0.0173532635389377 Q8IYU8,P80303,P43307,Q9Y376,Q14257,P41208,O43852,Q9BRK5,Q02818 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 296,9,48,148,85,116,184,90,125 184,324,2904,2827,116,48,2950,2385,9,125,85,1201,2959,1546,296,2549,3106,601,1217,90,148 1.6255321690560474,1.0445510616836513,-0.6988183969795223,-0.6490720698046804,2.083474851760708,3.155152877745957,-0.7237852836123975,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,-0.7237852836123975,-0.07032759590587762,1.1503444701717498,-0.5012978577516536,-0.8242894260138783,0.5452985658990057,0.09263033605246422,2.431035510324411,1.866485968870282 3430
Abnormality of head blood vessel 7 25 2.3667071366502976 0.0179471281963878 P17900,P06865,P07602,P03886,P16278,Q13510,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 89,99,36,15,179,313,25 3012,1853,1750,1576,15,99,36,918,25,2682,179,89,2824,1586,2828,994,2275,1660,313,707,1894,381,652,2089,657 -0.7739090091989397,-0.2120155691768394,-0.16457479426822091,-0.09381103021537567,4.652417670407559,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,-0.5749138732638202,1.6457867663301875,2.431035510324411,-0.6490720698046804,-0.09381103021537567,-0.6490720698046804,0.20754527371745304,-0.3797760297676727,-0.11734646334023954,1.0869803140135814,0.4338422448747199,-0.2120155691768394,0.937812905361756,0.5008477318133796,-0.28358176189719153,0.5008477318133796 3430
Sterol metabolic process 16 42 2.3646175309553747 0.0180486994958117 Q16850,Q15392,P61916,O15118,O76062,Q06520,Q8WTV0,P05067,Q15800,Q9BQE5,Q14739,P54646,P04062,P48449,Q9UBM7,Q14849 Processes and pathways GO Biological process msigdb_gobp 351,34,256,164,69,7,71,46,178,19,50,336,213,112,154,62 164,587,1421,69,1519,2901,213,46,3361,1990,519,2213,3384,857,385,3391,2644,112,2114,2382,3412,336,2537,256,1868,2591,7,3347,734,50,62,3099,34,1880,178,351,71,19,2141,154,1800,1376 1.7465774077703615,0.5452985658990057,-0.02351528122041195,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,3.191306028311356,-1.4505344444969863,-0.25967184066824295,0.6556730905320322,-0.35564345936189407,-1.8366930943997668,0.2986183093020084,0.9163495326117879,-1.9788713010588765,-0.5503155785430718,2.122543890584666,-0.30754673593761184,-0.42821167915506675,-2.360290770874015,1.0019706637911983,-0.5012978577516536,1.296917258531428,-0.2120155691768394,-0.5257770590663371,5.105496372209571,-1.3431986759033332,0.4114181815276483,3.1189087835415297,2.8441041534478297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,2.6953211040640213,4.3877182006716735,-0.30754673593761184,1.826640669391119,-0.16457479426822091,0.02309332399172761 3430
Endocytic vesicle membrane 11 40 2.3608264283610967 0.0182342627826359 Q15907,Q14108,Q5T9L3,Q8WTV0,Q03518,P11717,P01889,Q93050,P04439,Q9Y487,P13473 Localization GO Cellular component msigdb_gocc 389,130,230,71,74,330,329,45,335,24,217 985,1577,1925,1581,329,728,335,402,611,330,632,217,1237,2904,1027,2057,1115,1344,2538,2386,2167,2223,2389,921,74,1073,681,2498,2989,130,1598,2287,389,230,71,45,1676,1322,2974,24 0.20754527371745304,-0.09381103021537567,-0.23581657417804916,-0.09381103021537567,1.0232798624432902,0.4114181815276483,1.0019706637911983,0.8733052663722602,0.5230949161824157,1.0232798624432902,0.5008477318133796,1.4623099427802935,0.06950099771551356,-0.6988183969795223,0.18465877239643577,-0.28358176189719153,0.1387416835614649,0.02309332399172761,-0.5012978577516536,-0.42821167915506675,-0.33156716576876,-0.35564345936189407,-0.42821167915506675,0.25317576686812393,2.620328163937606,0.16172434863187643,0.45622167162433763,-0.4768775233718424,-0.7488153183487716,1.9852909461843653,-0.09381103021537567,-0.3797760297676727,0.9163495326117879,1.4211688103555455,2.6953211040640213,3.2093487244594585,-0.11734646334023954,0.04632210615831087,-0.7237852836123975,4.186254663337337 3430
Mitochondrial transmembrane transport 18 51 2.3360940223957263 0.0194863417869204 O60830,P56385,P21796,Q9BQT8,O43615,O95202,Q9BSK2,Q8IYU8,O94826,O43772,P23786,P24539,O75964,Q6P4A7,Q9H2D1,Q9Y619,O14925,Q99595 Processes and pathways GO Biological process msigdb_gobp 97,440,3,486,134,383,136,296,233,109,270,494,52,277,151,57,122,157 122,134,109,97,2317,1578,699,2262,52,233,383,1520,1930,2678,2049,491,3085,631,885,3,270,494,3111,1152,2831,2218,2381,3266,440,1350,820,2227,1538,277,296,899,1893,1083,827,157,486,136,151,1903,1326,1412,1092,977,697,948,57 2.0442894948035293,1.965565398534416,2.1420351304999743,2.3161817108012213,-0.4039652952055236,-0.09381103021537567,0.4338422448747199,-0.3797760297676727,3.1007524055777593,1.400546940102355,0.9163495326117879,-0.07032759590587762,-0.23581657417804916,-0.5749138732638202,-0.28358176189719153,0.6995273401513898,-0.8242894260138783,0.5008477318133796,0.2759203789757193,5.4060543445312685,1.2552190861703458,0.6995273401513898,-0.849577203134417,0.1157104547340278,-0.6490720698046804,-0.35564345936189407,-0.42821167915506675,-1.0801932550383022,0.8084416390325024,0.02309332399172761,0.3438753282799643,-0.35564345936189407,-0.07032759590587762,1.2343164607296082,1.1503444701717498,0.2759203789757193,-0.2120155691768394,0.16172434863187643,0.3438753282799643,1.8066716660719826,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.04632210615831087,-0.00018569005958125493,0.16172434863187643,0.23038416792428346,0.45622167162433763,0.25317576686812393,2.8994929547828066 3430
Vertebral segmentation defect 9 31 2.334921467738364 0.0195475236508286 O96028,P61978,P63241,Q9P2D1,Q9UHX1,O60826,Q6DKJ4,Q9Y619,Q9H9S5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 191,318,347,221,8,107,117,57,283 2897,1576,2725,107,2630,383,191,519,2161,3205,2980,2828,318,347,1660,1158,2797,707,117,825,870,283,2088,221,8,2089,1512,655,657,1230,57 -0.6988183969795223,-0.09381103021537567,-0.5995724062727221,2.1809317216381077,-0.5503155785430718,0.9163495326117879,1.6052450348577447,0.6556730905320322,-0.33156716576876,-0.977013463993979,-0.7488153183487716,-0.6490720698046804,1.0657844750365362,0.9806232501634713,-0.11734646334023954,0.1157104547340278,-0.6242916466860307,0.4338422448747199,2.083474851760708,0.3438753282799643,0.2986183093020084,1.213377883648462,-0.28358176189719153,1.4623099427802935,5.057543677692156,-0.28358176189719153,-0.04689579872958434,0.5008477318133796,0.5008477318133796,0.09263033605246422,2.8994929547828066 3430
Abnormal choroid morphology 13 30 2.32924143905922 0.0198462787651807 O14936,Q9P2D1,P40939,P40855,Q01082,O60826,Q8NAT1,O43505,O15078,P04439,P53701,Q9Y619,Q9H9S5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 530,221,386,577,483,107,273,146,304,335,276,57,283 530,304,146,2101,107,2726,1921,1931,335,2824,1340,1705,577,386,1817,634,276,483,921,1157,1158,768,896,3170,273,2607,1732,283,221,57 0.6336831437767028,1.1081387881403877,1.866485968870282,-0.30754673593761184,2.1809317216381077,-0.5995724062727221,-0.23581657417804916,-0.23581657417804916,1.0019706637911983,-0.6490720698046804,0.02309332399172761,-0.1409342612489813,0.567458949308088,0.9163495326117879,-0.18826843715602568,0.5008477318133796,1.2343164607296082,0.7213921450541884,0.25317576686812393,0.1157104547340278,0.1157104547340278,0.38894919874105743,0.2759203789757193,-0.900350577456945,1.2552190861703458,-0.5257770590663371,-0.1409342612489813,1.213377883648462,1.4623099427802935,2.8994929547828066 3430
Abnormal retinal artery morphology 7 22 2.325819141207538 0.0200282010643397 P17900,P06865,P07602,P03886,P16278,Q13510,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 89,99,36,15,179,313,25 3012,1750,1576,15,99,36,918,25,2682,179,89,1586,2828,2275,1660,313,707,1894,381,652,2089,657 -0.7739090091989397,-0.16457479426822091,-0.09381103021537567,4.652417670407559,2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,-0.5749138732638202,1.6457867663301875,2.431035510324411,-0.09381103021537567,-0.6490720698046804,-0.3797760297676727,-0.11734646334023954,1.0869803140135814,0.4338422448747199,-0.2120155691768394,0.937812905361756,0.5008477318133796,-0.28358176189719153,0.5008477318133796 3430
Oxidoreduction driven active transmembrane transporter activity 10 32 2.316957390766154 0.0205060529673413 O43676,P13073,Q9Y6M9,P51970,P00403,P03886,P14854,Q9P0J0,O75306,Q9UDW1 Functions GO Molecular function msigdb_gomf 35,409,373,425,394,15,424,211,309,284 698,2257,35,2775,2104,309,1697,1187,1920,753,2780,1579,610,394,15,1290,1522,409,424,2578,1025,2736,2688,439,3196,425,1950,1537,968,211,284,373 0.4338422448747199,-0.3797760297676727,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.07032759590587762,0.8517239183017473,0.8301027868261046,-0.5257770590663371,0.18465877239643577,-0.5995724062727221,-0.5749138732638202,0.8084416390325024,-0.9513913766449668,0.8301027868261046,-0.23581657417804916,-0.07032759590587762,0.23038416792428346,1.5033154527373318,1.213377883648462,0.9592374039290533 3430
Cis golgi network 6 16 2.3168520553997056 0.0205117922494131 O00461,Q08379,Q8TBA6,Q9NPR9,P24390,O43731 Localization GO Cellular component msigdb_gocc 33,387,198,41,13,123 33,123,855,13,920,762,387,398,1304,198,1674,1210,2754,1045,41,2365 3.7405615380913355,2.0246528531620718,0.2986183093020084,4.7179169525566556,0.25317576686812393,0.38894919874105743,0.9163495326117879,0.8948470616767685,0.04632210615831087,1.5849251978248329,-0.11734646334023954,0.09263033605246422,-0.5995724062727221,0.18465877239643577,3.35288880751217,-0.4039652952055236 3430
Submucous cleft of soft and hard palate 7 24 2.309608730585228 0.0209098258168187 Q15392,O43175,Q7LGA3,O75844,Q8NAT1,O43505,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 34,232,171,139,273,146,57 2201,232,146,139,954,2161,1342,994,1939,1485,2280,1869,1595,2285,34,171,825,273,581,1323,283,655,3355,57 -0.35564345936189407,1.400546940102355,1.866485968870282,1.9260244005596443,0.23038416792428346,-0.33156716576876,0.02309332399172761,0.20754527371745304,-0.23581657417804916,-0.04689579872958434,-0.3797760297676727,-0.2120155691768394,-0.09381103021537567,-0.3797760297676727,3.583187167896173,1.7063569746264826,0.3438753282799643,1.2552190861703458,0.567458949308088,0.04632210615831087,1.213377883648462,0.5008477318133796,-1.369914466388914,2.8994929547828066 3430
Respirasome 16 45 2.2981269196590843 0.0215545665266083 O43676,P13073,Q96CU9,Q9Y6M9,O14949,P51970,P00403,P03886,P14854,Q9P0J0,O75306,P22695,P14406,P47985,Q9UDW1,Q6DKK2 Localization GO Cellular component msigdb_gocc 35,409,103,373,243,425,394,15,424,211,309,274,56,439,284,31 698,2257,243,35,2775,2104,309,1697,1187,1920,753,2780,1579,610,394,15,1290,1477,1522,409,56,424,3204,3086,2578,1025,1763,274,2736,2583,2688,439,3196,425,764,1950,1537,31,968,474,103,211,284,2197,373 0.4338422448747199,-0.3797760297676727,1.338473936006947,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.04689579872958434,-0.07032759590587762,0.8517239183017473,2.9362983424259714,0.8301027868261046,-0.977013463993979,-0.8242894260138783,-0.5257770590663371,0.18465877239643577,-0.16457479426822091,1.2343164607296082,-0.5995724062727221,-0.5257770590663371,-0.5749138732638202,0.8084416390325024,-0.9513913766449668,0.8301027868261046,0.38894919874105743,-0.23581657417804916,-0.07032759590587762,3.7926560390546924,0.23038416792428346,0.7432157338415764,2.239063866307495,1.5033154527373318,1.213377883648462,-0.33156716576876,0.9592374039290533 3430
Glycosphingolipid metabolic process 6 10 2.295576510199812 0.0217001071292248 P06865,P04062,O60512,P16278,P17900,P06280 Processes and pathways GO Biological process msigdb_gobp 99,213,150,179,89,156 150,213,156,99,918,179,89,1824,617,381 1.8465787199040886,1.4828295622266432,1.8066716660719826,2.277678317409277,0.25317576686812393,1.6457867663301875,2.431035510324411,-0.18826843715602568,0.5230949161824157,0.937812905361756 3430
Cherry red spot of the macula 6 10 2.2747964698272014 0.0229181421113175 P06865,P07602,Q13510,P16278,P17900,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 99,36,313,179,89,25 99,36,918,25,2682,179,89,313,381,652 2.277678317409277,3.495034957042614,0.25317576686812393,4.1354813465701925,-0.5749138732638202,1.6457867663301875,2.431035510324411,1.0869803140135814,0.937812905361756,0.5008477318133796 3430
Decreased activity of mitochondrial complex i 10 36 2.2298271280187216 0.0257589216872247 Q9Y584,O43676,Q70HW3,Q96CU9,Q9Y6M9,P51970,P03886,O75306,Q86Y39,Q9UBX3 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,35,102,103,373,425,15,309,474,189 698,35,2104,309,1697,1920,1062,610,15,2578,2736,1937,3196,425,1592,2116,471,2454,102,474,898,2182,2608,103,1501,1455,2891,2760,1509,1142,875,721,189,2199,96,373 0.4338422448747199,3.512707326927762,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,-0.23581657417804916,0.16172434863187643,0.5230949161824157,4.652417670407559,-0.5257770590663371,-0.5995724062727221,-0.23581657417804916,-0.9513913766449668,0.8301027868261046,-0.09381103021537567,-0.30754673593761184,0.7432157338415764,-0.4525156104496164,2.239063866307495,0.7432157338415764,0.2759203789757193,-0.33156716576876,-0.5257770590663371,2.239063866307495,-0.04689579872958434,-0.02351528122041195,-0.6739141572295496,-0.5995724062727221,-0.04689579872958434,0.1387416835614649,0.2986183093020084,0.4338422448747199,1.6255321690560474,-0.33156716576876,2.3353920752424693,0.9592374039290533 3430
Azurophil granule lumen 13 44 2.202416603953538 0.0276358940795211 Q9BTY2,P61916,O00754,O00584,O00560,Q9H7Z7,P08236,P16278,P17900,P10619,P06280,P15586,Q9Y5Z4 Localization GO Cellular component msigdb_gocc 128,256,66,249,300,143,246,179,89,25,156,218,322 300,249,66,811,2901,1422,156,2105,2106,918,246,25,2159,730,218,179,89,1650,2870,1940,3162,2382,2328,2166,2694,256,2589,1434,2915,2448,1824,618,1776,2134,580,1500,2022,1793,357,128,143,3258,2362,322 1.1292601049826305,1.3177131892594451,2.8070566341243905,0.3438753282799643,-0.6988183969795223,-0.02351528122041195,1.8066716660719826,-0.30754673593761184,-0.30754673593761184,0.25317576686812393,1.338473936006947,4.1354813465701925,-0.33156716576876,0.4114181815276483,1.4623099427802935,1.6457867663301875,2.431035510324411,-0.11734646334023954,-0.6739141572295496,-0.23581657417804916,-0.900350577456945,-0.42821167915506675,-0.4039652952055236,-0.33156716576876,-0.5749138732638202,1.296917258531428,-0.5257770590663371,-0.02351528122041195,-0.6988183969795223,-0.4525156104496164,-0.18826843715602568,0.5230949161824157,-0.16457479426822091,-0.30754673593761184,0.567458949308088,-0.04689579872958434,-0.25967184066824295,-0.16457479426822091,0.9806232501634713,2.0049867171526095,1.906208661011561,-1.0542934068429035,-0.4039652952055236,1.0657844750365362 3430
Endoplasmic reticulum golgi intermediate compartment membrane 10 26 2.201197483247645 0.0277220464003515 Q12907,Q8N511,Q08379,P49257,Q03518,P24390,Q13190,O15260,Q10472,Q9Y282 Localization GO Cellular component msigdb_gocc 413,67,387,263,74,13,496,149,469,61 149,950,985,1577,13,2904,263,762,2380,2329,74,1073,387,469,413,496,2601,522,67,1895,775,3301,2190,61,2365,2036 1.8465787199040886,0.23038416792428346,0.20754527371745304,-0.09381103021537567,4.7179169525566556,-0.6988183969795223,1.2760859545124026,0.38894919874105743,-0.42821167915506675,-0.4039652952055236,2.620328163937606,0.16172434863187643,0.9163495326117879,0.7432157338415764,0.8517239183017473,0.6995273401513898,-0.5257770590663371,0.6556730905320322,2.8070566341243905,-0.2120155691768394,0.38894919874105743,-1.15832093411627,-0.33156716576876,2.8625913164326255,-0.4039652952055236,-0.25967184066824295 3430
Membrane lipid biosynthetic process 6 22 2.1983991839423087 0.0279206718058482 Q96G23,P27544,O95470,O60512,P04062,Q06136 Processes and pathways GO Biological process msigdb_gobp 68,82,147,150,213,59 548,1633,502,150,1805,147,213,1649,82,1824,59,313,1305,3124,1007,1962,68,2965,1620,1278,1688,1973 0.6116509767559337,-0.11734646334023954,0.6776210718932071,1.8465787199040886,-0.18826843715602568,1.866485968870282,1.4828295622266432,-0.11734646334023954,2.54492504446314,-0.18826843715602568,2.8625913164326255,1.0869803140135814,0.04632210615831087,-0.849577203134417,0.20754527371745304,-0.23581657417804916,2.7884960733515816,-0.7237852836123975,-0.09381103021537567,0.06950099771551356,-0.11734646334023954,-0.23581657417804916 3430
Establishment of protein localization to mitochondrial membrane 9 19 2.19704065721711 0.0280175426529836 Q9Y584,Q15070,Q9Y5J9,P0DP25,O14737,O94826,Q9P0J0,Q9Y5L4,Q9NS69 Processes and pathways GO Biological process msigdb_gobp 96,350,225,324,70,233,211,183,23 809,70,233,661,324,2687,2944,617,350,1305,1083,23,211,2197,546,96,421,225,183 0.3438753282799643,2.6953211040640213,1.400546940102355,0.4785567416325205,1.0445510616836513,-0.5749138732638202,-0.7237852836123975,0.5230949161824157,0.9806232501634713,0.04632210615831087,0.16172434863187643,4.236863344428605,1.5033154527373318,-0.33156716576876,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875 3430
Negative regulation of mrna catabolic process 12 24 2.1955044537093262 0.0281274317723188 Q9Y2W1,O60506,P98175,Q99729,Q14011,P35637,P11940,P07910,Q14103,Q06787,Q92804,P67809 Processes and pathways GO Biological process msigdb_gobp 584,292,397,430,426,140,518,517,443,153,187,252 744,292,1518,517,518,140,252,397,2063,153,1825,2917,2391,637,426,443,1440,1668,1961,187,430,1220,1687,584 0.38894919874105743,1.171392087430195,-0.07032759590587762,0.6556730905320322,0.6556730905320322,1.9260244005596443,1.3177131892594451,0.8948470616767685,-0.28358176189719153,1.826640669391119,-0.18826843715602568,-0.6988183969795223,-0.42821167915506675,0.5008477318133796,0.8301027868261046,0.8084416390325024,-0.02351528122041195,-0.11734646334023954,-0.23581657417804916,1.6255321690560474,0.8301027868261046,0.09263033605246422,-0.11734646334023954,0.567458949308088 3430
SLC superfamily of solute carriers 14 41 2.1927813113967787 0.0283231390547265 Q9BQT8,O95202,Q70HW3,Q9BSK2,Q9H2V7,O43772,P55011,Q15043,Q9H2D1,Q6NUK1,Q9Y619,Q8TB61,Q9UBX3,Q8IXU6 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 486,383,102,136,104,109,495,365,151,472,57,92,189,127 1469,109,1855,699,383,1520,2049,1988,1338,631,885,504,2381,1657,495,1350,1247,365,1121,3392,472,3103,102,127,92,827,3227,486,136,903,1010,151,104,1903,1326,652,189,977,57,834,835 -0.04689579872958434,2.1420351304999743,-0.2120155691768394,0.4338422448747199,0.9163495326117879,-0.07032759590587762,-0.28358176189719153,-0.25967184066824295,0.02309332399172761,0.5008477318133796,0.2759203789757193,0.6776210718932071,-0.42821167915506675,-0.11734646334023954,0.6995273401513898,0.02309332399172761,0.06950099771551356,0.9592374039290533,0.1387416835614649,-1.9788713010588765,0.7432157338415764,-0.8242894260138783,2.239063866307495,2.0049867171526095,2.4119608690616183,0.3438753282799643,-1.0027041076562464,0.7213921450541884,1.965565398534416,0.2759203789757193,0.20754527371745304,1.8465787199040886,2.2197146760906703,-0.2120155691768394,0.04632210615831087,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643,0.3438753282799643 3430
Regulation of alternative mrna splicing via spliceosome 9 33 2.185569742898433 0.028847098282958 P51116,P98175,Q9UHX1,P38159,P31483,P51114,Q07666,Q06787,P52756 Processes and pathways GO Biological process msigdb_gobp 197,397,8,262,364,87,403,153,507 3260,2321,1933,2268,1646,2640,364,262,1528,87,197,507,1071,397,2063,153,403,2497,1876,1878,2070,795,2181,1169,1498,1503,1406,719,1138,8,584,1182,1230 -1.0801932550383022,-0.4039652952055236,-0.23581657417804916,-0.3797760297676727,-0.11734646334023954,-0.5503155785430718,0.9592374039290533,1.2760859545124026,-0.07032759590587762,2.4691045637919236,1.5849251978248329,0.6776210718932071,0.16172434863187643,0.8948470616767685,-0.28358176189719153,1.826640669391119,0.8733052663722602,-0.4768775233718424,-0.2120155691768394,-0.2120155691768394,-0.28358176189719153,0.36643501064183787,-0.33156716576876,0.1157104547340278,-0.04689579872958434,-0.04689579872958434,-0.00018569005958125493,0.4338422448747199,0.1387416835614649,5.057543677692156,0.567458949308088,0.1157104547340278,0.09263033605246422 3430
Protein transmembrane transport 7 25 2.185084971544912 0.0288826169431983 Q15629,Q9Y584,O60830,O43615,Q9NS69,O14925,Q99595 Processes and pathways GO Biological process msigdb_gobp 64,96,97,134,23,122,157 122,134,97,2726,233,1930,2678,3085,729,762,1817,3382,3116,2834,1248,820,64,1538,2459,1216,157,1412,23,653,96 2.0442894948035293,1.965565398534416,2.3161817108012213,-0.5995724062727221,1.400546940102355,-0.23581657417804916,-0.5749138732638202,-0.8242894260138783,0.4114181815276483,0.38894919874105743,-0.18826843715602568,-1.8085387445922683,-0.849577203134417,-0.6490720698046804,0.06950099771551356,0.3438753282799643,2.825592626630927,-0.07032759590587762,-0.4525156104496164,0.09263033605246422,1.8066716660719826,-0.00018569005958125493,4.236863344428605,0.5008477318133796,2.3353920752424693 3430
Proton transmembrane transporter activity 12 35 2.183320007480901 0.0290122521608329 P56385,P13073,O95202,Q93050,P00403,P14854,P24539,Q96ES6,O75964,Q9Y487,P47985,Q9UDW1 Functions GO Molecular function msigdb_gomf 440,409,383,45,394,424,494,18,52,24,439,284 2262,52,383,394,2049,491,1290,1522,631,409,424,1025,3205,3321,494,3111,2688,1152,663,992,439,2831,3266,440,2167,1350,764,968,45,18,1903,284,2032,24,808 -0.3797760297676727,3.1007524055777593,0.9163495326117879,0.8948470616767685,-0.28358176189719153,0.6995273401513898,0.04632210615831087,-0.07032759590587762,0.5008477318133796,0.8517239183017473,0.8301027868261046,0.18465877239643577,-0.977013463993979,-1.2371040916101648,0.6995273401513898,-0.849577203134417,-0.5749138732638202,0.1157104547340278,0.4785567416325205,0.20754527371745304,0.8084416390325024,-0.6490720698046804,-1.0801932550383022,0.8084416390325024,-0.33156716576876,0.02309332399172761,0.38894919874105743,0.23038416792428346,3.2093487244594585,4.404391230829396,-0.2120155691768394,1.213377883648462,-0.25967184066824295,4.186254663337337,0.36643501064183787 3430
Antigen binding 6 10 2.181095311098165 0.0291763675900802 Q15392,Q03518,P01889,P10321,P04439,P55899 Functions GO Molecular function msigdb_gomf 34,74,329,402,335,287 985,329,335,402,532,287,74,1073,34,1839 0.20754527371745304,1.0232798624432902,1.0019706637911983,0.8733052663722602,0.6336831437767028,1.1924031585962547,2.620328163937606,0.16172434863187643,3.583187167896173,-0.18826843715602568 3430
Agitation 6 33 2.176346383561083 0.0295293696854255 Q15165,P35637,P05067,P42892,P48449,Q92804 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,140,46,49,112,187 1186,1638,2678,213,46,1475,1933,589,2941,857,140,412,49,858,112,614,2793,634,2166,483,1944,2391,766,1777,1,3150,1164,1205,2128,187,3127,3393,2560 0.09263033605246422,-0.11734646334023954,-0.5749138732638202,1.4828295622266432,3.191306028311356,-0.04689579872958434,-0.23581657417804916,0.5452985658990057,-0.7237852836123975,0.2986183093020084,1.9260244005596443,0.8517239183017473,3.1189087835415297,0.2986183093020084,2.122543890584666,0.5230949161824157,-0.6242916466860307,0.5008477318133796,-0.33156716576876,0.7213921450541884,-0.23581657417804916,-0.42821167915506675,0.38894919874105743,-0.16457479426822091,6.5440889483340765,-0.8749307389569164,0.1157104547340278,0.09263033605246422,-0.30754673593761184,1.6255321690560474,-0.849577203134417,-1.9788713010588765,-0.5012978577516536 3430
Sphingolipid metabolism 6 12 2.1709282581723435 0.029936595870077 O95470,P04062,P16278,Q13510,Q06136,P06280 Processes and pathways KEGG Pathways msigdb_kegg 147,213,179,313,59,156 548,1633,811,147,213,156,730,179,59,313,381,1278 0.6116509767559337,-0.11734646334023954,0.3438753282799643,1.866485968870282,1.4828295622266432,1.8066716660719826,0.4114181815276483,1.6457867663301875,2.8625913164326255,1.0869803140135814,0.937812905361756,0.06950099771551356 3430
Metallopeptidase activity 11 41 2.164640192434577 0.0304152504963859 Q99797,Q9NZ08,O75844,Q9UIQ6,Q969V3,O75976,P42892,O95630,P22695,P55786,Q5JRX3 Functions GO Molecular function msigdb_gomf 199,299,139,12,172,142,49,245,274,152,126 2314,2625,748,951,1578,139,142,245,728,311,2324,2267,274,3143,1068,49,3322,1654,2220,152,1157,126,793,1309,2346,543,172,2847,1320,1008,199,3171,1175,2303,3045,3187,2716,299,12,1628,948 -0.4039652952055236,-0.5503155785430718,0.38894919874105743,0.23038416792428346,-0.09381103021537567,1.9260244005596443,1.906208661011561,1.338473936006947,0.4114181815276483,1.0869803140135814,-0.4039652952055236,-0.3797760297676727,1.2343164607296082,-0.8749307389569164,0.16172434863187643,3.1189087835415297,-1.2371040916101648,-0.11734646334023954,-0.35564345936189407,1.826640669391119,0.1157104547340278,2.0049867171526095,0.36643501064183787,0.04632210615831087,-0.4039652952055236,0.6336831437767028,1.7063569746264826,-0.6490720698046804,0.04632210615831087,0.20754527371745304,1.5849251978248329,-0.900350577456945,0.1157104547340278,-0.3797760297676727,-0.7739090091989397,-0.9258372702304992,-0.5749138732638202,1.1503444701717498,4.766868416503872,-0.09381103021537567,0.25317576686812393 3430
Calmodulin 7 16 2.16358866847065 0.0304959319692155 Q8IYU8,P80303,P41208,Q14257,O43852,Q9BRK5,Q02818 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 296,9,116,85,184,90,125 184,324,2827,116,2950,2385,9,125,85,1201,2959,1546,296,2549,601,90 1.6255321690560474,1.0445510616836513,-0.6490720698046804,2.083474851760708,-0.7237852836123975,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,-0.7237852836123975,-0.07032759590587762,1.1503444701717498,-0.5012978577516536,0.5452985658990057,2.431035510324411 3430
Intracellular calcium-sensing protein 7 16 2.16358866847065 0.0304959319692155 Q8IYU8,P80303,P41208,Q14257,O43852,Q9BRK5,Q02818 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 296,9,116,85,184,90,125 184,324,2827,116,2950,2385,9,125,85,1201,2959,1546,296,2549,601,90 1.6255321690560474,1.0445510616836513,-0.6490720698046804,2.083474851760708,-0.7237852836123975,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,-0.7237852836123975,-0.07032759590587762,1.1503444701717498,-0.5012978577516536,0.5452985658990057,2.431035510324411 3430
Rna stabilization 12 27 2.1630452884772806 0.0305376964984662 Q9Y2W1,O60506,P98175,Q9H2U1,Q14011,P35637,P11940,P07910,O95453,Q14103,Q92804,P67809 Processes and pathways GO Biological process msigdb_gobp 584,292,397,431,426,140,518,517,119,443,187,252 292,2861,1518,119,517,518,140,252,397,2063,1825,1869,2917,2391,637,426,443,1440,1668,1961,187,1041,1220,431,904,1687,584 1.171392087430195,-0.6739141572295496,-0.07032759590587762,2.063896781548296,0.6556730905320322,0.6556730905320322,1.9260244005596443,1.3177131892594451,0.8948470616767685,-0.28358176189719153,-0.18826843715602568,-0.2120155691768394,-0.6988183969795223,-0.42821167915506675,0.5008477318133796,0.8301027868261046,0.8084416390325024,-0.02351528122041195,-0.11734646334023954,-0.23581657417804916,1.6255321690560474,0.18465877239643577,0.09263033605246422,0.8301027868261046,0.2759203789757193,-0.11734646334023954,0.567458949308088 3430
Vacuole organization 9 53 2.157663092965657 0.0309540354086246 Q14108,Q8N511,P50897,P54802,O75503,P10253,Q8TBX8,P11117,O14773 Processes and pathways GO Biological process msigdb_gobp 130,67,6,40,138,144,176,79,121 809,121,1577,138,1926,1754,1699,1700,213,2105,918,144,79,886,482,1114,6,2057,40,1768,2540,2168,1158,130,665,2500,1598,1304,1078,1163,1834,642,67,176,1674,1732,1895,2888,3127,2190,1221,1047,1741,2358,1178,1627,2974,979,2034,1913,3284,2367,2038 0.3438753282799643,2.0442894948035293,-0.09381103021537567,1.9260244005596443,-0.23581657417804916,-0.16457479426822091,-0.1409342612489813,-0.1409342612489813,1.4828295622266432,-0.30754673593761184,0.25317576686812393,1.8863625663085712,2.5638146678084146,0.2759203789757193,0.7213921450541884,0.1387416835614649,5.121449989369716,-0.28358176189719153,3.370732425976295,-0.16457479426822091,-0.5012978577516536,-0.33156716576876,0.1157104547340278,1.9852909461843653,0.4785567416325205,-0.4768775233718424,-0.09381103021537567,0.04632210615831087,0.16172434863187643,0.1157104547340278,-0.18826843715602568,0.5008477318133796,2.8070566341243905,1.6861990067024655,-0.11734646334023954,-0.1409342612489813,-0.2120155691768394,-0.6739141572295496,-0.849577203134417,-0.33156716576876,0.09263033605246422,0.18465877239643577,-0.1409342612489813,-0.4039652952055236,0.1157104547340278,-0.09381103021537567,-0.7237852836123975,0.23038416792428346,-0.25967184066824295,-0.2120155691768394,-1.1061640452367623,-0.4039652952055236,-0.25967184066824295 3430
calmodulin-related 7 14 2.156530850765918 0.0310422374725023 Q8IYU8,P80303,P41208,Q14257,O43852,Q9BRK5,Q02818 Functions Panther Protein class panther_protein_class 296,9,116,85,184,90,125 184,324,2943,2827,116,2385,9,125,85,1201,296,3106,601,90 1.6255321690560474,1.0445510616836513,-0.7237852836123975,-0.6490720698046804,2.083474851760708,-0.42821167915506675,4.993390704618005,2.0246528531620718,2.4880992123030645,0.09263033605246422,1.1503444701717498,-0.8242894260138783,0.5452985658990057,2.431035510324411 3430
Bruising susceptibility 13 32 2.1530193676820377 0.0313171564402816 Q14108,Q15149,Q9NWM8,P49257,P10644,P51798,Q13126,P38435,O60568,P04062,Q96L58,Q6UN15,O15360 Drugs and Diseases Human Phenotype Ontology msigdb_hp 130,454,137,263,589,520,205,145,550,213,215,540,433 2773,433,550,213,2434,589,2160,3233,2980,1650,2482,1110,145,2113,1814,263,1653,520,2280,1533,1824,2281,205,130,1875,454,540,215,648,137,1465,1180 -0.6242916466860307,0.8084416390325024,0.6116509767559337,1.4828295622266432,-0.4525156104496164,0.5452985658990057,-0.33156716576876,-1.0284638912585382,-0.7488153183487716,-0.11734646334023954,-0.4768775233718424,0.1387416835614649,1.8863625663085712,-0.30754673593761184,-0.18826843715602568,1.2760859545124026,-0.11734646334023954,0.6556730905320322,-0.3797760297676727,-0.07032759590587762,-0.18826843715602568,-0.3797760297676727,1.5441867444483162,1.9852909461843653,-0.2120155691768394,0.7867402397027633,0.6336831437767028,1.4828295622266432,0.5008477318133796,1.9458099313348363,-0.02351528122041195,0.1157104547340278 3430
Ventricular hypertrophy 13 40 2.14925775971296 0.0316139729163653 Q96MF7,P40939,P46976,O75844,O43772,P00403,P03886,P10253,P23786,P14854,O95630,Q9H9S5,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,386,331,139,109,394,15,144,270,424,245,283,156 2773,109,1335,139,752,245,394,954,15,156,144,2635,631,1645,424,1763,270,2583,1389,1706,663,3247,386,2948,331,2646,841,1947,2499,709,472,1605,2294,2608,290,1134,1140,1738,283,1909 -0.6242916466860307,2.1420351304999743,0.02309332399172761,1.9260244005596443,0.38894919874105743,1.338473936006947,0.8948470616767685,0.23038416792428346,4.652417670407559,1.8066716660719826,1.8863625663085712,-0.5503155785430718,0.5008477318133796,-0.11734646334023954,0.8301027868261046,-0.16457479426822091,1.2552190861703458,-0.5257770590663371,-0.00018569005958125493,-0.1409342612489813,0.4785567416325205,-1.0542934068429035,0.9163495326117879,-0.7237852836123975,1.0232798624432902,-0.5503155785430718,0.32126985958171844,-0.23581657417804916,-0.4768775233718424,0.4338422448747199,0.7432157338415764,-0.09381103021537567,-0.3797760297676727,-0.5257770590663371,1.1924031585962547,0.1387416835614649,0.1387416835614649,-0.1409342612489813,1.213377883648462,-0.2120155691768394 3430
Clumsiness 14 21 2.143835878008909 0.032046039478556 P42858,O14773,P15289,O00754,P07602,Q9NZJ7,O75503,P31483,Q05086,O43819,Q13510,O43681,Q9NR77,Q15067 Drugs and Diseases Human Phenotype Ontology msigdb_hp 412,121,730,66,36,652,138,364,595,360,313,811,60,666 66,121,1853,811,360,138,813,36,730,2583,364,412,595,313,666,2805,967,1134,60,652,1225 2.8070566341243905,2.0442894948035293,-0.2120155691768394,0.3438753282799643,0.9592374039290533,1.9260244005596443,0.3438753282799643,3.495034957042614,0.4114181815276483,-0.5257770590663371,0.9592374039290533,0.8517239183017473,0.5452985658990057,1.0869803140135814,0.4785567416325205,-0.6242916466860307,0.23038416792428346,0.1387416835614649,2.8625913164326255,0.5008477318133796,0.09263033605246422 3430
Cytochrome complex assembly 7 12 2.1426419142979967 0.032141862817651 Q15070,Q9BSK2,Q9Y2R0,O43819,P53701,Q69YU5,Q6DKK2 Processes and pathways GO Biological process msigdb_gobp 350,136,81,360,276,30,31 360,752,439,276,350,30,31,968,136,3190,2197,81 0.9592374039290533,0.38894919874105743,0.8084416390325024,1.2343164607296082,0.9806232501634713,3.861838008707718,3.7926560390546924,0.23038416792428346,1.965565398534416,-0.9258372702304992,-0.33156716576876,2.5638146678084146 3430
Monovalent inorganic cation homeostasis 10 28 2.1245407084655232 0.0336249557944114 Q8N511,Q15904,P50897,O75503,Q93050,P55011,P06576,Q9Y5X3,Q9Y487,Q92544 Processes and pathways GO Biological process msigdb_gobp 67,522,6,138,45,495,491,574,24,511 138,1754,1642,1423,491,2158,2581,1650,6,2057,2384,495,2167,595,522,67,511,45,1732,2888,1215,903,2421,2032,24,574,3403,835 1.9260244005596443,-0.16457479426822091,-0.11734646334023954,-0.02351528122041195,0.6995273401513898,-0.33156716576876,-0.5257770590663371,-0.11734646334023954,5.121449989369716,-0.28358176189719153,-0.42821167915506675,0.6995273401513898,-0.33156716576876,0.5452985658990057,0.6556730905320322,2.8070566341243905,0.6776210718932071,3.2093487244594585,-0.1409342612489813,-0.6739141572295496,0.09263033605246422,0.2759203789757193,-0.42821167915506675,-0.25967184066824295,4.186254663337337,0.5895763319810627,-2.211483395059946,0.3438753282799643 3430
Electron transport 17 46 2.1226415601616053 0.0337838995379646 Q16134,Q86Y39,O43676,Q96CU9,Q9Y6M9,O14949,P51970,P00403,P03886,Q9P0J0,Q9H1E5,O75306,O43169,P22695,P47985,Q9UDW1,Q6DKK2 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 224,474,35,103,373,243,425,394,15,211,279,309,55,274,439,284,31 698,2257,243,55,467,35,2775,2104,309,1697,1187,1920,753,2780,1579,2373,610,394,15,1290,3175,3204,2578,1763,2213,274,2736,2583,2688,3248,439,3196,425,224,1950,1537,2603,31,474,103,2557,279,1736,211,284,373 0.4338422448747199,-0.3797760297676727,1.338473936006947,2.9546651894343055,0.7432157338415764,3.512707326927762,-0.6242916466860307,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,0.09263033605246422,-0.23581657417804916,0.38894919874105743,-0.6242916466860307,-0.09381103021537567,-0.42821167915506675,0.5230949161824157,0.8948470616767685,4.652417670407559,0.04632210615831087,-0.9258372702304992,-0.977013463993979,-0.5257770590663371,-0.16457479426822091,-0.35564345936189407,1.2343164607296082,-0.5995724062727221,-0.5257770590663371,-0.5749138732638202,-1.0542934068429035,0.8084416390325024,-0.9513913766449668,0.8301027868261046,1.4417564181063023,-0.23581657417804916,-0.07032759590587762,-0.5257770590663371,3.7926560390546924,0.7432157338415764,2.239063866307495,-0.5012978577516536,1.2343164607296082,-0.1409342612489813,1.5033154527373318,1.213377883648462,0.9592374039290533 3430
Sterol metabolism 10 26 2.103386470923036 0.0354320001129395 Q16850,Q15392,P61916,O15118,O76062,Q15800,Q14739,P54646,P04062,Q9UBM7 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 351,34,256,164,69,178,50,336,213,154 164,587,1421,69,1519,2901,213,1990,2213,857,385,3412,336,256,1868,2591,3347,50,3099,34,1880,178,351,154,1800,1376 1.7465774077703615,0.5452985658990057,-0.02351528122041195,2.714006070492743,-0.07032759590587762,-0.6988183969795223,1.4828295622266432,-0.25967184066824295,-0.35564345936189407,0.2986183093020084,0.9163495326117879,-2.360290770874015,1.0019706637911983,1.296917258531428,-0.2120155691768394,-0.5257770590663371,-1.3431986759033332,3.1189087835415297,-0.8242894260138783,3.583187167896173,-0.2120155691768394,1.6660089911781828,0.9806232501634713,1.826640669391119,-0.16457479426822091,0.02309332399172761 3430
Retrograde vesicle mediated transport golgi to endoplasmic reticulum 7 27 2.1010419956309203 0.0356372799257465 P42858,P24390,Q9P2W9,O43731,Q8TD16,Q9Y282,Q6NUQ1 Processes and pathways GO Biological process msigdb_gobp 412,13,177,123,314,61,258 744,1057,1854,985,123,1577,531,13,760,412,1864,1938,762,2058,2951,1943,2118,413,258,314,1674,1210,2754,776,177,2419,61 0.38894919874105743,0.16172434863187643,-0.2120155691768394,0.20754527371745304,2.0246528531620718,-0.09381103021537567,0.6336831437767028,4.7179169525566556,0.38894919874105743,0.8517239183017473,-0.2120155691768394,-0.23581657417804916,0.38894919874105743,-0.28358176189719153,-0.7237852836123975,-0.23581657417804916,-0.30754673593761184,0.8517239183017473,1.296917258531428,1.0869803140135814,-0.11734646334023954,0.09263033605246422,-0.5995724062727221,0.38894919874105743,1.6861990067024655,-0.42821167915506675,2.8625913164326255 3430
Heterogeneous 13 47 2.099378790217319 0.0357835228618343 P61916,Q15555,P40939,Q16836,P11717,O75844,P01889,P05067,P03886,Q8TB36,Q9BQE5,Q9Y619,Q9NR77 Drugs and Diseases Human Phenotype Ontology msigdb_hp 256,265,386,42,330,139,329,46,15,368,19,57,60 1918,2572,787,139,2728,423,329,954,15,2680,1383,46,813,1106,330,631,1856,1586,1705,1424,1813,386,1428,1027,2793,520,2874,256,2595,1250,2545,894,766,265,1880,42,2883,368,2607,3420,1735,19,1844,60,1414,2037,57 -0.23581657417804916,-0.5257770590663371,0.36643501064183787,1.9260244005596443,-0.5995724062727221,0.8301027868261046,1.0232798624432902,0.23038416792428346,4.652417670407559,-0.5749138732638202,-0.00018569005958125493,3.191306028311356,0.3438753282799643,0.1387416835614649,1.0232798624432902,0.5008477318133796,-0.2120155691768394,-0.09381103021537567,-0.1409342612489813,-0.02351528122041195,-0.18826843715602568,0.9163495326117879,-0.02351528122041195,0.18465877239643577,-0.6242916466860307,0.6556730905320322,-0.6739141572295496,1.296917258531428,-0.5257770590663371,0.06950099771551356,-0.5012978577516536,0.2759203789757193,0.38894919874105743,1.2760859545124026,-0.2120155691768394,3.3350234117032413,-0.6739141572295496,0.9592374039290533,-0.5257770590663371,-2.9207032885706705,-0.1409342612489813,4.3877182006716735,-0.18826843715602568,2.8625913164326255,-0.00018569005958125493,-0.25967184066824295,2.8994929547828066 3430
Abnormality of pulmonary circulation 12 31 2.099025641748188 0.0358146404207186 Q14108,Q9NZ08,O75844,P51970,P00403,P03886,Q8IZA0,P14854,P01889,P04062,Q6NUK1,O14678 Drugs and Diseases Human Phenotype Ontology msigdb_hp 130,299,139,425,394,15,272,424,329,213,472,466 466,3334,139,2781,610,394,329,954,15,213,2635,424,1025,2980,2824,3111,1652,1428,1653,520,425,130,2748,2993,1722,472,272,1732,1740,299,2368 0.7432157338415764,-1.31656044562432,1.9260244005596443,-0.6242916466860307,0.5230949161824157,0.8948470616767685,1.0232798624432902,0.23038416792428346,4.652417670407559,1.4828295622266432,-0.5503155785430718,0.8301027868261046,0.18465877239643577,-0.7488153183487716,-0.6490720698046804,-0.849577203134417,-0.11734646334023954,-0.02351528122041195,-0.11734646334023954,0.6556730905320322,0.8301027868261046,1.9852909461843653,-0.5995724062727221,-0.7488153183487716,-0.1409342612489813,0.7432157338415764,1.2552190861703458,-0.1409342612489813,-0.1409342612489813,1.1503444701717498,-0.4039652952055236 3430
Bulbar signs 7 13 2.092422498816832 0.0364007379082944 P07602,Q9Y263,P35637,Q99720,P03886,P04062,Q15043 Drugs and Diseases Human Phenotype Ontology msigdb_hp 36,527,140,47,15,213,365 811,15,213,813,36,730,140,858,365,523,47,652,527 0.3438753282799643,4.652417670407559,1.4828295622266432,0.3438753282799643,3.495034957042614,0.4114181815276483,1.9260244005596443,0.2986183093020084,0.9592374039290533,0.6556730905320322,3.173240775887535,0.5008477318133796,0.6556730905320322 3430
Dementia 18 58 2.0858150691568813 0.036995377873342 P17900,Q14108,P61916,P07602,Q9Y287,O15118,P06865,P35637,P00403,P03886,P05067,P31483,P27544,P04062,Q9Y487,Q13510,Q06787,O60313 Drugs and Diseases Human Phenotype Ontology msigdb_hp 89,130,256,36,166,164,99,140,394,15,46,364,82,213,24,313,153,94 915,164,811,94,1186,812,2678,394,15,213,2322,1641,46,99,36,1933,2732,730,89,564,1763,576,2111,82,2583,364,140,663,992,412,858,2793,840,2166,256,1662,1944,153,2391,313,130,766,1399,1205,2128,3170,2460,1082,1790,3127,499,1134,3393,652,722,166,24,2368 0.25317576686812393,1.7465774077703615,0.3438753282799643,2.35457505060863,0.09263033605246422,0.3438753282799643,-0.5749138732638202,0.8948470616767685,4.652417670407559,1.4828295622266432,-0.4039652952055236,-0.11734646334023954,3.191306028311356,2.277678317409277,3.495034957042614,-0.23581657417804916,-0.5995724062727221,0.4114181815276483,2.431035510324411,0.5895763319810627,-0.16457479426822091,0.567458949308088,-0.30754673593761184,2.54492504446314,-0.5257770590663371,0.9592374039290533,1.9260244005596443,0.4785567416325205,0.20754527371745304,0.8517239183017473,0.2986183093020084,-0.6242916466860307,0.32126985958171844,-0.33156716576876,1.296917258531428,-0.11734646334023954,-0.23581657417804916,1.826640669391119,-0.42821167915506675,1.0869803140135814,1.9852909461843653,0.38894919874105743,-0.00018569005958125493,0.09263033605246422,-0.30754673593761184,-0.900350577456945,-0.4525156104496164,0.16172434863187643,-0.16457479426822091,-0.849577203134417,0.6995273401513898,0.1387416835614649,-1.9788713010588765,0.5008477318133796,0.4338422448747199,1.7465774077703615,4.186254663337337,-0.4039652952055236 3430
Mitochondrial substrate/solute carrier [IPR018108] 10 20 2.078414386499124 0.0376712087853632 Q9BQT8,Q70HW3,Q9BSK2,P12235,O43772,Q9H2D1,Q6NUK1,Q9Y619,Q9NZJ7,Q9UBX3 Sequence InterPro Repeat interpro_repeat 486,102,136,631,109,151,472,57,652,189 109,1855,699,2049,631,885,2381,1350,1247,472,102,486,136,151,1903,652,189,977,57,834 2.1420351304999743,-0.2120155691768394,0.4338422448747199,-0.28358176189719153,0.5008477318133796,0.2759203789757193,-0.42821167915506675,0.02309332399172761,0.06950099771551356,0.7432157338415764,2.239063866307495,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643 3430
Mitochondrial carrier domain superfamily [IPR023395] 10 20 2.078414386499124 0.0376712087853632 Q9BQT8,Q70HW3,Q9BSK2,P12235,O43772,Q9H2D1,Q6NUK1,Q9Y619,Q9NZJ7,Q9UBX3 Sequence InterPro Superfamily interpro_homologous_superfamily 486,102,136,631,109,151,472,57,652,189 109,1855,699,2049,631,885,2381,1350,1247,472,102,486,136,151,1903,652,189,977,57,834 2.1420351304999743,-0.2120155691768394,0.4338422448747199,-0.28358176189719153,0.5008477318133796,0.2759203789757193,-0.42821167915506675,0.02309332399172761,0.06950099771551356,0.7432157338415764,2.239063866307495,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643 3430
SLC25 family of mitochondrial transporters 10 20 2.078414386499124 0.0376712087853632 Q9BQT8,Q70HW3,Q9BSK2,P12235,O43772,Q9H2D1,Q6NUK1,Q9Y619,Q9NZJ7,Q9UBX3 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 486,102,136,631,109,151,472,57,652,189 109,1855,699,2049,631,885,2381,1350,1247,472,102,486,136,151,1903,652,189,977,57,834 2.1420351304999743,-0.2120155691768394,0.4338422448747199,-0.28358176189719153,0.5008477318133796,0.2759203789757193,-0.42821167915506675,0.02309332399172761,0.06950099771551356,0.7432157338415764,2.239063866307495,0.7213921450541884,1.965565398534416,1.8465787199040886,-0.2120155691768394,0.5008477318133796,1.6255321690560474,0.23038416792428346,2.8994929547828066,0.3438753282799643 3430
Confusion 6 19 2.076281867547062 0.0378678893319728 O00754,Q16836,Q9NZ08,P01889,P05067,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 66,42,299,329,46,57 66,1853,2678,329,46,2820,1338,758,1760,2111,2787,1068,386,1653,42,299,977,2368,57 2.8070566341243905,-0.2120155691768394,-0.5749138732638202,1.0232798624432902,3.191306028311356,-0.6490720698046804,0.02309332399172761,0.38894919874105743,-0.16457479426822091,-0.30754673593761184,-0.6242916466860307,0.16172434863187643,0.9163495326117879,-0.11734646334023954,3.3350234117032413,1.1503444701717498,0.23038416792428346,-0.4039652952055236,2.8994929547828066 3430
Udp glycosyltransferase activity 8 17 2.07271291706947 0.0381990049233122 P06865,P46976,Q8NAT1,O43505,O60512,Q96L58,Q8N4A0,Q10472 Functions GO Molecular function msigdb_gomf 99,331,273,146,150,215,281,469 1982,146,952,150,550,99,918,1645,331,732,469,1126,281,273,1263,215,782 -0.25967184066824295,1.866485968870282,0.23038416792428346,1.8465787199040886,0.6116509767559337,2.277678317409277,0.25317576686812393,-0.11734646334023954,1.0232798624432902,0.4114181815276483,0.7432157338415764,0.1387416835614649,1.213377883648462,1.2552190861703458,0.06950099771551356,1.4828295622266432,0.38894919874105743 3430
Gingival overgrowth 10 30 2.0706796765629343 0.0383887407178173 O00754,Q99519,P10644,Q14739,P08236,P16278,Q6DKJ4,Q6UN15,Q9UBM7,P20700 Drugs and Diseases Human Phenotype Ontology msigdb_hp 66,381,589,50,246,179,117,540,154,564 66,1576,952,1421,1699,2434,246,589,179,564,3205,2828,2113,1709,1660,1870,2333,50,1875,707,117,540,1959,1554,2965,381,154,2089,1512,657 2.8070566341243905,-0.09381103021537567,0.23038416792428346,-0.02351528122041195,-0.1409342612489813,-0.4525156104496164,1.338473936006947,0.5452985658990057,1.6457867663301875,0.5895763319810627,-0.977013463993979,-0.6490720698046804,-0.30754673593761184,-0.1409342612489813,-0.11734646334023954,-0.2120155691768394,-0.4039652952055236,3.1189087835415297,-0.2120155691768394,0.4338422448747199,2.083474851760708,0.6336831437767028,-0.23581657417804916,-0.07032759590587762,-0.7237852836123975,0.937812905361756,1.826640669391119,-0.28358176189719153,-0.04689579872958434,0.5008477318133796 3430
Micromelia 8 24 2.0640871548519675 0.039009453641319 P48735,Q15392,Q96HY6,Q9UHX1,O43175,Q14739,Q9UBM7,O75874 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,34,294,8,232,50,154,286 744,3218,232,2725,2044,2630,361,286,516,589,129,1591,537,1777,50,34,2175,2297,294,1909,154,8,1097,3355 0.38894919874105743,-1.0027041076562464,1.400546940102355,-0.5995724062727221,-0.28358176189719153,-0.5503155785430718,0.9592374039290533,1.1924031585962547,0.6556730905320322,0.5452985658990057,1.9852909461843653,-0.09381103021537567,0.6336831437767028,-0.16457479426822091,3.1189087835415297,3.583187167896173,-0.33156716576876,-0.3797760297676727,1.171392087430195,-0.2120155691768394,1.826640669391119,5.057543677692156,0.16172434863187643,-1.369914466388914 3430
Organic acid transmembrane transport 8 29 2.0601062540281285 0.0393883841356295 P08183,Q9BQT8,O43772,P23786,Q9H2D1,Q9Y619,Q9UBX3,O14678 Processes and pathways GO Biological process msigdb_gobp 323,486,109,270,151,57,189,466 466,109,2935,699,1985,1520,856,323,1988,1338,270,1192,504,2642,2218,2381,1657,1247,964,1121,773,827,486,151,1903,1326,189,977,57 0.7432157338415764,2.1420351304999743,-0.7237852836123975,0.4338422448747199,-0.25967184066824295,-0.07032759590587762,0.2986183093020084,1.0445510616836513,-0.25967184066824295,0.02309332399172761,1.2552190861703458,0.09263033605246422,0.6776210718932071,-0.5503155785430718,-0.35564345936189407,-0.42821167915506675,-0.11734646334023954,0.06950099771551356,0.23038416792428346,0.1387416835614649,0.38894919874105743,0.3438753282799643,0.7213921450541884,1.8465787199040886,-0.2120155691768394,0.04632210615831087,1.6255321690560474,0.23038416792428346,2.8994929547828066 3430
Disproportionate short limb short stature 11 24 2.043627509936031 0.040990359436545 Q96MF7,Q15392,P42345,Q7LGA3,Q9UBN7,Q14739,O75718,Q32P28,Q6DKJ4,P10644,Q9UBM7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,34,482,171,500,50,361,247,117,589,154 1183,606,3218,2630,361,589,3244,482,1864,1118,1664,1828,50,34,247,117,171,2297,2610,290,1909,154,500,1467 0.09263033605246422,0.5230949161824157,-1.0027041076562464,-0.5503155785430718,0.9592374039290533,0.5452985658990057,-1.0542934068429035,0.7213921450541884,-0.2120155691768394,0.1387416835614649,-0.11734646334023954,-0.18826843715602568,3.1189087835415297,3.583187167896173,1.338473936006947,2.083474851760708,1.7063569746264826,-0.3797760297676727,-0.5257770590663371,1.1924031585962547,-0.2120155691768394,1.826640669391119,0.6995273401513898,-0.02351528122041195 3430
Slender long bone 7 15 2.0427067002174857 0.0410814811626061 Q96MF7,Q96J02,P37268,Q32P28,Q96L58,Q9Y487,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,295,385,247,215,24,57 516,2161,385,2341,247,2958,1962,295,215,290,1323,1047,1620,24,57 0.6556730905320322,-0.33156716576876,0.9163495326117879,-0.4039652952055236,1.338473936006947,-0.7237852836123975,-0.23581657417804916,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,0.18465877239643577,-0.09381103021537567,4.186254663337337,2.8994929547828066 3430
Intrinsic component of mitochondrial inner membrane 19 30 2.0423791947434062 0.0411139318811191 Q8NE86,Q5XKP0,Q16891,Q9Y512,Q6P4A7,Q99595,Q9NVH1,Q9NX63,Q96NB2,Q13505,Q6UXV4,Q9Y2R0,Q16134,Q15070,O60830,O43819,Q9H9P8,O14925,O75880 Localization GO Cellular component msigdb_gocc 899,896,405,546,277,157,829,298,827,596,844,81,224,350,97,360,777,122,752 122,360,97,1335,752,1520,2643,2908,1350,596,350,224,405,1305,896,277,844,899,827,157,2661,3394,1326,777,829,298,2307,81,948,546 2.0442894948035293,0.9592374039290533,2.3161817108012213,0.02309332399172761,0.38894919874105743,-0.07032759590587762,-0.5503155785430718,-0.6988183969795223,0.02309332399172761,0.5452985658990057,0.9806232501634713,1.4417564181063023,0.8733052663722602,0.04632210615831087,0.2759203789757193,1.2343164607296082,0.32126985958171844,0.2759203789757193,0.3438753282799643,1.8066716660719826,-0.5503155785430718,-1.9788713010588765,0.04632210615831087,0.38894919874105743,0.3438753282799643,1.1503444701717498,-0.3797760297676727,2.5638146678084146,0.25317576686812393,0.6336831437767028 3430
Abnormal arterial physiology 7 30 2.040947604428506 0.0412560353452537 Q9NWM8,Q9NZ08,O75844,P01889,P05067,Q14739,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 137,299,139,329,46,50,156 1573,434,1576,550,2937,139,329,954,2680,46,156,2161,2904,2482,1705,2828,1653,2165,1530,1660,1533,50,707,2011,2014,137,299,2089,1229,657 -0.09381103021537567,0.8084416390325024,-0.09381103021537567,0.6116509767559337,-0.7237852836123975,1.9260244005596443,1.0232798624432902,0.23038416792428346,-0.5749138732638202,3.191306028311356,1.8066716660719826,-0.33156716576876,-0.6988183969795223,-0.4768775233718424,-0.1409342612489813,-0.6490720698046804,-0.11734646334023954,-0.33156716576876,-0.07032759590587762,-0.11734646334023954,-0.07032759590587762,3.1189087835415297,0.4338422448747199,-0.25967184066824295,-0.25967184066824295,1.9458099313348363,1.1503444701717498,-0.28358176189719153,0.09263033605246422,0.5008477318133796 3430
Phagocytic vesicle membrane 7 23 2.0346410816142124 0.0418870005535669 Q15907,Q03518,P01889,Q93050,P04439,Q9Y487,P13473 Localization GO Cellular component msigdb_gocc 389,74,329,45,335,24,217 985,1577,329,335,402,611,632,217,2904,1027,2057,1115,2538,2386,2167,921,74,1073,389,45,1322,2974,24 0.20754527371745304,-0.09381103021537567,1.0232798624432902,1.0019706637911983,0.8733052663722602,0.5230949161824157,0.5008477318133796,1.4623099427802935,-0.6988183969795223,0.18465877239643577,-0.28358176189719153,0.1387416835614649,-0.5012978577516536,-0.42821167915506675,-0.33156716576876,0.25317576686812393,2.620328163937606,0.16172434863187643,0.9163495326117879,3.2093487244594585,0.04632210615831087,-0.7237852836123975,4.186254663337337 3430
Retinal detachment 7 16 2.033645193252392 0.0419873817386389 Q96MF7,Q99496,Q8NAT1,O43505,P04439,O75533,Q9H9S5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,559,273,146,335,588,283 146,588,335,1705,1653,634,1533,922,1664,273,290,559,283,1626,1465,1693 1.866485968870282,0.5452985658990057,1.0019706637911983,-0.1409342612489813,-0.11734646334023954,0.5008477318133796,-0.07032759590587762,0.25317576686812393,-0.11734646334023954,1.2552190861703458,1.1924031585962547,0.6116509767559337,1.213377883648462,-0.09381103021537567,-0.02351528122041195,-0.11734646334023954 3430
Hyperlipidemia 10 30 2.033367879163404 0.0420153699948198 Q96MF7,P49257,Q92734,O43707,P50402,O75844,P23786,P28070,O95470,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,263,523,479,396,139,270,80,147,156 1853,479,1335,139,147,954,156,1583,1765,270,80,955,1389,3391,263,396,2218,2874,922,1664,1947,1258,557,523,1962,290,1794,977,1053,2931 -0.2120155691768394,0.7213921450541884,0.02309332399172761,1.9260244005596443,1.866485968870282,0.23038416792428346,1.8066716660719826,-0.09381103021537567,-0.16457479426822091,1.2552190861703458,2.5638146678084146,0.23038416792428346,-0.00018569005958125493,-1.9788713010588765,1.2760859545124026,0.8948470616767685,-0.35564345936189407,-0.6739141572295496,0.25317576686812393,-0.11734646334023954,-0.23581657417804916,0.06950099771551356,0.6116509767559337,0.6556730905320322,-0.23581657417804916,1.1924031585962547,-0.16457479426822091,0.23038416792428346,0.18465877239643577,-0.6988183969795223 3430
Nuclear inner membrane 7 23 2.029637364301258 0.0423934139775941 O76062,O75844,P50402,Q99720,Q14739,Q8IXM6,Q9H1E5 Localization GO Cellular component msigdb_gocc 69,139,396,47,50,242,279 139,69,628,564,1863,858,396,2387,1071,441,1663,866,50,1884,2124,242,3211,1791,47,1794,279,1416,2254 1.9260244005596443,2.714006070492743,0.5008477318133796,0.5895763319810627,-0.2120155691768394,0.2986183093020084,0.8948470616767685,-0.42821167915506675,0.16172434863187643,0.8084416390325024,-0.11734646334023954,0.2986183093020084,3.1189087835415297,-0.2120155691768394,-0.30754673593761184,1.359199686384635,-0.977013463993979,-0.16457479426822091,3.173240775887535,-0.16457479426822091,1.2343164607296082,-0.00018569005958125493,-0.35564345936189407 3430
Hallucinations 9 48 2.0270781466499805 0.0426544213858199 O00754,P07602,P50897,O75503,P35637,P05067,Q9BQE5,O60313,Q6DKK2 Drugs and Diseases Human Phenotype Ontology msigdb_hp 66,36,6,138,140,46,19,94,31 3343,915,66,811,94,1186,138,812,2678,213,46,36,2820,2323,730,2161,2437,2579,1586,2787,140,1068,412,1428,1026,2908,6,2832,1656,2166,2221,1944,2067,2391,3184,31,1205,2128,367,2460,3127,3393,19,1274,652,977,2197,2368 -1.3431986759033332,0.25317576686812393,2.8070566341243905,0.3438753282799643,2.35457505060863,0.09263033605246422,1.9260244005596443,0.3438753282799643,-0.5749138732638202,1.4828295622266432,3.191306028311356,3.495034957042614,-0.6490720698046804,-0.4039652952055236,0.4114181815276483,-0.33156716576876,-0.4525156104496164,-0.5257770590663371,-0.09381103021537567,-0.6242916466860307,1.9260244005596443,0.16172434863187643,0.8517239183017473,-0.02351528122041195,0.18465877239643577,-0.6988183969795223,5.121449989369716,-0.6490720698046804,-0.11734646334023954,-0.33156716576876,-0.35564345936189407,-0.23581657417804916,-0.28358176189719153,-0.42821167915506675,-0.9258372702304992,3.7926560390546924,0.09263033605246422,-0.30754673593761184,0.9592374039290533,-0.4525156104496164,-0.849577203134417,-1.9788713010588765,4.3877182006716735,0.06950099771551356,0.5008477318133796,0.23038416792428346,-0.33156716576876,-0.4039652952055236 3430
Signaling 6 20 2.023029657816916 0.0430700898886355 O15173,P43490,Q8WUJ1,P17931,O00264,Q96PC5 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 344,11,76,301,239,193 239,344,2320,301,1391,11,1865,617,1248,2917,705,792,379,1206,76,1895,739,193,1615,2421 1.359199686384635,0.9806232501634713,-0.4039652952055236,1.1292601049826305,-0.00018569005958125493,4.864332563034109,-0.2120155691768394,0.5230949161824157,0.06950099771551356,-0.6988183969795223,0.4338422448747199,0.36643501064183787,0.937812905361756,0.09263033605246422,2.601516115344004,-0.2120155691768394,0.4114181815276483,1.6052450348577447,-0.09381103021537567,-0.42821167915506675 3430
Regulation of endothelial cell migration 7 30 2.015566036984118 0.0438453742144349 P57105,P42785,Q8WTV0,P09429,P04083,P09601,Q9H6U6 Processes and pathways GO Biological process msigdb_gobp 227,38,71,363,83,20,419 1573,1232,1753,2523,660,83,1383,491,1758,363,20,632,2051,2160,2270,2824,1587,3111,2904,38,2793,227,2833,2446,1593,2393,71,1791,419,1414 -0.09381103021537567,0.06950099771551356,-0.16457479426822091,-0.5012978577516536,0.4785567416325205,2.5260093370892096,-0.00018569005958125493,0.6995273401513898,-0.16457479426822091,0.9592374039290533,4.337593478683959,0.5008477318133796,-0.28358176189719153,-0.33156716576876,-0.3797760297676727,-0.6490720698046804,-0.09381103021537567,-0.849577203134417,-0.6988183969795223,3.441890793303961,-0.6242916466860307,1.4211688103555455,-0.6490720698046804,-0.4525156104496164,-0.09381103021537567,-0.42821167915506675,2.6953211040640213,-0.16457479426822091,0.8517239183017473,-0.00018569005958125493 3430
Mitochondrial membrane organization 16 50 2.0134016739123144 0.0440723896575072 Q9Y584,Q15070,Q9Y5J9,P0DP25,O95202,O14737,Q9NX63,O94826,Q16891,Q9P0J0,Q9Y5L4,Q9NS69,P45880,Q9UII2,Q9Y5Z4,O60313 Processes and pathways GO Biological process msigdb_gobp 96,350,225,324,383,70,298,233,405,211,183,23,26,222,322,94 809,70,94,1334,1335,233,383,2680,2049,661,1932,324,631,2737,2687,2944,2643,2644,26,1113,2792,1817,1297,617,596,350,405,1538,1305,896,844,714,1168,643,1083,2661,3394,23,829,298,211,222,2197,948,546,96,421,225,183,322 0.3438753282799643,2.6953211040640213,2.35457505060863,0.02309332399172761,0.02309332399172761,1.400546940102355,0.9163495326117879,-0.5749138732638202,-0.28358176189719153,0.4785567416325205,-0.23581657417804916,1.0445510616836513,0.5008477318133796,-0.5995724062727221,-0.5749138732638202,-0.7237852836123975,-0.5503155785430718,-0.5503155785430718,4.1354813465701925,0.1387416835614649,-0.6242916466860307,-0.18826843715602568,0.04632210615831087,0.5230949161824157,0.5452985658990057,0.9806232501634713,0.8733052663722602,-0.07032759590587762,0.04632210615831087,0.2759203789757193,0.32126985958171844,0.4338422448747199,0.1157104547340278,0.5008477318133796,0.16172434863187643,-0.5503155785430718,-1.9788713010588765,4.236863344428605,0.3438753282799643,1.1503444701717498,1.5033154527373318,1.4623099427802935,-0.33156716576876,0.25317576686812393,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875,1.0657844750365362 3430
Mitochondrial fusion 10 14 2.012270655392658 0.0441914139900909 Q9NQG6,P02786,Q9UJZ1,Q9NX63,Q8N2A8,Q8TB36,Q8NAN2,Q8IWA4,Q07812,O60313 Processes and pathways GO Biological process msigdb_gobp 259,728,697,298,427,368,51,714,617,94 94,728,617,1607,714,427,51,368,1793,259,298,697,948,834 2.35457505060863,0.4114181815276483,0.5230949161824157,-0.09381103021537567,0.4338422448747199,0.8301027868261046,3.1189087835415297,0.9592374039290533,-0.16457479426822091,1.296917258531428,1.1503444701717498,0.45622167162433763,0.25317576686812393,0.3438753282799643 3430
Lysosomal transport 9 44 2.011724282423196 0.0442490094425729 Q14108,P07602,O15118,Q9Y2T2,P11717,Q99523,Q96L92,P13473,Q9UNK0 Processes and pathways GO Biological process msigdb_gobp 130,36,164,106,330,78,188,217,260 809,2153,359,2315,164,1803,1285,1754,36,1584,611,330,217,1237,1296,2057,1115,2166,681,130,2174,2882,2701,684,933,2408,1732,188,3127,78,1044,1140,1221,1738,2358,652,1375,1178,1799,1279,1627,979,260,106 0.3438753282799643,-0.33156716576876,0.9592374039290533,-0.4039652952055236,1.7465774077703615,-0.18826843715602568,0.04632210615831087,-0.16457479426822091,3.495034957042614,-0.09381103021537567,0.5230949161824157,1.0232798624432902,1.4623099427802935,0.06950099771551356,0.04632210615831087,-0.28358176189719153,0.1387416835614649,-0.33156716576876,0.45622167162433763,1.9852909461843653,-0.33156716576876,-0.6739141572295496,-0.5749138732638202,0.45622167162433763,0.25317576686812393,-0.42821167915506675,-0.1409342612489813,1.6255321690560474,-0.849577203134417,2.5826783205648556,0.18465877239643577,0.1387416835614649,0.09263033605246422,-0.1409342612489813,-0.4039652952055236,0.5008477318133796,0.02309332399172761,0.1157104547340278,-0.16457479426822091,0.06950099771551356,-0.09381103021537567,0.23038416792428346,1.296917258531428,2.2197146760906703 3430
Regulation of blood pressure 6 19 2.0062158171918747 0.044833227019184 P42785,P09493,Q9UIQ6,Q9HB40,P42892,P09601 Processes and pathways GO Biological process msigdb_gobp 38,201,12,17,49,20 3352,1423,201,20,3160,503,38,49,2792,2793,2833,3237,999,793,1048,17,299,12,574 -1.369914466388914,-0.02351528122041195,1.5645724906173264,4.337593478683959,-0.900350577456945,0.6776210718932071,3.441890793303961,3.1189087835415297,-0.6242916466860307,-0.6242916466860307,-0.6490720698046804,-1.0284638912585382,0.20754527371745304,0.36643501064183787,0.18465877239643577,4.454305506671291,1.1503444701717498,4.766868416503872,0.5895763319810627 3430
Abnormal thoracic spine morphology 7 31 2.0004992558528123 0.0454463801927673 O00754,Q96J02,Q9UHX1,O75844,P08236,P04062,P51648 Drugs and Diseases Human Phenotype Ontology msigdb_hp 66,295,8,139,246,213,223 1573,982,66,2627,952,2630,587,139,1421,1930,954,213,813,246,758,1760,2580,3235,1817,223,1533,2499,2957,3212,1732,2555,2610,295,873,400,8 -0.09381103021537567,0.20754527371745304,2.8070566341243905,-0.5503155785430718,0.23038416792428346,-0.5503155785430718,0.5452985658990057,1.9260244005596443,-0.02351528122041195,-0.23581657417804916,0.23038416792428346,1.4828295622266432,0.3438753282799643,1.338473936006947,0.38894919874105743,-0.16457479426822091,-0.5257770590663371,-1.0284638912585382,-0.18826843715602568,1.4417564181063023,-0.07032759590587762,-0.4768775233718424,-0.7237852836123975,-0.977013463993979,-0.1409342612489813,-0.5012978577516536,-0.5257770590663371,1.171392087430195,0.2986183093020084,0.8948470616767685,5.057543677692156 3430
Platyspondyly 13 35 1.9982421094760323 0.0456904182900725 P48735,O00754,Q96HY6,Q9UBN7,Q14739,P08236,Q32P28,Q96AY3,P16278,Q96L58,Q6NUK1,Q6NUQ1,O75874 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,66,294,500,50,246,247,448,179,215,472,258,286 2624,66,3218,952,550,2630,286,2431,1930,1422,246,179,2980,3244,2440,1862,129,1591,995,921,1533,50,2957,247,792,472,258,1494,448,2610,294,215,2715,500,2309 -0.5503155785430718,2.8070566341243905,-1.0027041076562464,0.23038416792428346,0.6116509767559337,-0.5503155785430718,1.1924031585962547,-0.4525156104496164,-0.23581657417804916,-0.02351528122041195,1.338473936006947,1.6457867663301875,-0.7488153183487716,-1.0542934068429035,-0.4525156104496164,-0.2120155691768394,1.9852909461843653,-0.09381103021537567,0.20754527371745304,0.25317576686812393,-0.07032759590587762,3.1189087835415297,-0.7237852836123975,1.338473936006947,0.36643501064183787,0.7432157338415764,1.296917258531428,-0.04689579872958434,0.8084416390325024,-0.5257770590663371,1.171392087430195,1.4828295622266432,-0.5749138732638202,0.6995273401513898,-0.3797760297676727 3430
Ventricular arrhythmia 11 43 1.9973303390934016 0.0457893096662012 P0DP25,P46976,P09493,P50402,O43772,P23786,P03886,P10253,P42892,O75306,P13473 Drugs and Diseases Human Phenotype Ontology msigdb_hp 324,331,201,396,109,270,15,144,49,309,217 109,2572,309,1637,394,954,15,755,1642,2820,201,324,144,631,217,2051,1856,2437,1763,270,1706,1068,2871,49,331,2114,2908,396,1299,2745,1947,894,1719,1038,1450,557,2608,1732,1134,623,1045,1794,3213 2.1420351304999743,-0.5257770590663371,1.0869803140135814,-0.11734646334023954,0.8948470616767685,0.23038416792428346,4.652417670407559,0.38894919874105743,-0.11734646334023954,-0.6490720698046804,1.5645724906173264,1.0445510616836513,1.8863625663085712,0.5008477318133796,1.4623099427802935,-0.28358176189719153,-0.2120155691768394,-0.4525156104496164,-0.16457479426822091,1.2552190861703458,-0.1409342612489813,0.16172434863187643,-0.6739141572295496,3.1189087835415297,1.0232798624432902,-0.30754673593761184,-0.6988183969795223,0.8948470616767685,0.04632210615831087,-0.5995724062727221,-0.23581657417804916,0.2759203789757193,-0.1409342612489813,0.18465877239643577,-0.02351528122041195,0.6116509767559337,-0.5257770590663371,-0.1409342612489813,0.1387416835614649,0.5230949161824157,0.18465877239643577,-0.16457479426822091,-0.977013463993979 3430
Abnormal delivery 7 22 1.996593385183712 0.045869372017957 O75844,Q6YHK3,O75718,Q9Y487,Q9UBM7,O60313,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 139,463,361,24,154,94,57 1853,94,361,139,3220,954,813,2161,2326,1591,1027,483,1533,463,1833,3211,1501,1458,2087,154,24,57 -0.2120155691768394,2.35457505060863,0.9592374039290533,1.9260244005596443,-1.0027041076562464,0.23038416792428346,0.3438753282799643,-0.33156716576876,-0.4039652952055236,-0.09381103021537567,0.18465877239643577,0.7213921450541884,-0.07032759590587762,0.7649983512811526,-0.18826843715602568,-0.977013463993979,-0.04689579872958434,-0.02351528122041195,-0.28358176189719153,1.826640669391119,4.186254663337337,2.8994929547828066 3430
Ascites 9 29 1.994534403713033 0.0460936840883163 Q14108,P61916,P63241,O15118,Q14739,P08236,P04062,Q13510,Q01844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 130,256,347,164,50,246,213,313,124 164,786,2261,1472,2781,213,246,589,788,2822,2271,3391,2165,1941,256,347,593,1394,124,1662,1713,313,130,50,1829,381,2145,1909,3048 1.7465774077703615,0.36643501064183787,-0.3797760297676727,-0.04689579872958434,-0.6242916466860307,1.4828295622266432,1.338473936006947,0.5452985658990057,0.36643501064183787,-0.6490720698046804,-0.3797760297676727,-1.9788713010588765,-0.33156716576876,-0.23581657417804916,1.296917258531428,0.9806232501634713,0.5452985658990057,-0.00018569005958125493,2.0246528531620718,-0.11734646334023954,-0.1409342612489813,1.0869803140135814,1.9852909461843653,3.1189087835415297,-0.18826843715602568,0.937812905361756,-0.30754673593761184,-0.2120155691768394,-0.7739090091989397 3430
Telangiectasia 8 38 1.9925895448990425 0.0463064109721933 Q13535,P03886,Q8IZA0,Q14739,O75306,O95453,P10619,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 348,15,272,50,309,119,25,156 1805,2861,309,953,119,954,15,156,2434,25,2375,2324,758,1760,2824,1763,955,1705,3247,1814,2444,1866,537,1713,1250,1664,348,50,2174,2014,272,739,2559,381,2611,2142,3008,2420 -0.18826843715602568,-0.6739141572295496,1.0869803140135814,0.23038416792428346,2.063896781548296,0.23038416792428346,4.652417670407559,1.8066716660719826,-0.4525156104496164,4.1354813465701925,-0.42821167915506675,-0.4039652952055236,0.38894919874105743,-0.16457479426822091,-0.6490720698046804,-0.16457479426822091,0.23038416792428346,-0.1409342612489813,-1.0542934068429035,-0.18826843715602568,-0.4525156104496164,-0.2120155691768394,0.6336831437767028,-0.1409342612489813,0.06950099771551356,-0.11734646334023954,0.9806232501634713,3.1189087835415297,-0.33156716576876,-0.25967184066824295,1.2552190861703458,0.4114181815276483,-0.5012978577516536,0.937812905361756,-0.5257770590663371,-0.30754673593761184,-0.7488153183487716,-0.42821167915506675 3430
Severe short stature 7 24 1.9805430064933505 0.0476425458530798 Q96MF7,Q15392,P16278,Q96L58,P53701,Q9Y619,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 290,34,179,215,276,57,25 3218,2897,2630,25,179,1763,2440,2583,1862,2643,994,634,276,840,537,34,2958,3170,1501,294,215,290,1323,57 -1.0027041076562464,-0.6988183969795223,-0.5503155785430718,4.1354813465701925,1.6457867663301875,-0.16457479426822091,-0.4525156104496164,-0.5257770590663371,-0.2120155691768394,-0.5503155785430718,0.20754527371745304,0.5008477318133796,1.2343164607296082,0.32126985958171844,0.6336831437767028,3.583187167896173,-0.7237852836123975,-0.900350577456945,-0.04689579872958434,1.171392087430195,1.4828295622266432,1.1924031585962547,0.04632210615831087,2.8994929547828066 3430
Azurophil granule membrane 7 22 1.976785004085192 0.0480659374706435 P07602,P42785,Q07065,P10253,O15260,Q9NQX7,P13473 Localization GO Cellular component msigdb_gocc 36,38,113,144,149,220,217 149,2629,3157,1186,36,144,611,217,2112,38,2163,1115,113,1078,1729,341,3282,3171,1010,220,652,1973 1.8465787199040886,-0.5503155785430718,-0.900350577456945,0.09263033605246422,3.495034957042614,1.8863625663085712,0.5230949161824157,1.4623099427802935,-0.30754673593761184,3.441890793303961,-0.33156716576876,0.1387416835614649,2.122543890584666,0.16172434863187643,-0.1409342612489813,1.0019706637911983,-1.1061640452367623,-0.900350577456945,0.20754527371745304,1.4623099427802935,0.5008477318133796,-0.23581657417804916 3430
Protein localization to mitochondrion 21 59 1.9739480742604516 0.0483876475731555 O43615,P49257,Q9NS69,P55786,Q9Y5J7,Q99595,Q9Y5L4,P0DP25,O14737,Q99797,Q9P0J0,Q9UII2,Q8N4H5,Q9Y584,Q15070,Q9Y5J9,O60830,O94826,Q8TB36,O14925,Q5JRX3 Processes and pathways GO Biological process msigdb_gobp 134,263,23,152,421,157,183,324,70,199,211,222,95,96,350,225,97,233,368,122,126 2773,809,915,70,122,134,97,1578,233,2631,1289,1700,1930,2678,661,324,3085,435,2376,3142,2687,1194,1810,2944,263,2792,2380,1297,152,2914,617,1157,350,820,2802,1538,1305,126,1607,95,368,1083,559,157,199,649,1412,23,211,3290,222,2197,3284,546,96,421,225,183,834 -0.6242916466860307,0.3438753282799643,0.25317576686812393,2.6953211040640213,2.0442894948035293,1.965565398534416,2.3161817108012213,-0.09381103021537567,1.400546940102355,-0.5503155785430718,0.04632210615831087,-0.1409342612489813,-0.23581657417804916,-0.5749138732638202,0.4785567416325205,1.0445510616836513,-0.8242894260138783,0.8084416390325024,-0.42821167915506675,-0.8749307389569164,-0.5749138732638202,0.09263033605246422,-0.18826843715602568,-0.7237852836123975,1.2760859545124026,-0.6242916466860307,-0.42821167915506675,0.04632210615831087,1.826640669391119,-0.6988183969795223,0.5230949161824157,0.1157104547340278,0.9806232501634713,0.3438753282799643,-0.6242916466860307,-0.07032759590587762,0.04632210615831087,2.0049867171526095,-0.09381103021537567,2.35457505060863,0.9592374039290533,0.16172434863187643,0.6116509767559337,1.8066716660719826,1.5849251978248329,0.5008477318133796,-0.00018569005958125493,4.236863344428605,1.5033154527373318,-1.1322063957742325,1.4623099427802935,-0.33156716576876,-1.1061640452367623,0.6336831437767028,2.3353920752424693,0.8517239183017473,1.4417564181063023,1.6457867663301875,0.3438753282799643 3430
Muscle abnormality related to mitochondrial dysfunction 10 37 1.9734395561923808 0.0484455046505949 O43676,Q96CU9,Q9Y6M9,P14854,P00403,P03886,Q9Y2R0,O75306,Q9UBX3,O60313 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,103,373,424,394,15,81,309,189,94 698,2257,35,94,2104,309,1697,1920,1062,3219,610,394,15,631,424,2578,2736,1863,3196,2116,1305,474,898,2182,1893,103,1134,2891,2469,2764,875,721,189,81,2721,1570,373 0.4338422448747199,-0.3797760297676727,3.512707326927762,2.35457505060863,-0.30754673593761184,1.0869803140135814,-0.1409342612489813,-0.23581657417804916,0.16172434863187643,-1.0027041076562464,0.5230949161824157,0.8948470616767685,4.652417670407559,0.5008477318133796,0.8301027868261046,-0.5257770590663371,-0.5995724062727221,-0.2120155691768394,-0.9513913766449668,-0.30754673593761184,0.04632210615831087,0.7432157338415764,0.2759203789757193,-0.33156716576876,-0.2120155691768394,2.239063866307495,0.1387416835614649,-0.6739141572295496,-0.4525156104496164,-0.5995724062727221,0.2986183093020084,0.4338422448747199,1.6255321690560474,2.5638146678084146,-0.5749138732638202,-0.07032759590587762,0.9592374039290533 3430
Hexosyltransferase activity 12 36 1.968080603496111 0.0490587642243649 Q6ZXV5,P06865,Q2TAA5,P46976,Q13126,Q8NAT1,O43505,O60512,P04062,Q96L58,Q8N4A0,Q10472 Functions GO Molecular function msigdb_gomf 289,99,556,331,205,273,146,150,213,215,281,469 2624,1982,146,952,150,550,1805,2523,213,917,1384,1583,99,918,2159,1645,1389,331,1815,1533,1662,732,469,205,556,289,1126,281,273,1263,1673,215,941,1970,3416,782 -0.5503155785430718,-0.25967184066824295,1.866485968870282,0.23038416792428346,1.8465787199040886,0.6116509767559337,-0.18826843715602568,-0.5012978577516536,1.4828295622266432,0.25317576686812393,-0.00018569005958125493,-0.09381103021537567,2.277678317409277,0.25317576686812393,-0.33156716576876,-0.11734646334023954,-0.00018569005958125493,1.0232798624432902,-0.18826843715602568,-0.07032759590587762,-0.11734646334023954,0.4114181815276483,0.7432157338415764,1.5441867444483162,0.6116509767559337,1.1924031585962547,0.1387416835614649,1.213377883648462,1.2552190861703458,0.06950099771551356,-0.11734646334023954,1.4828295622266432,0.25317576686812393,-0.23581657417804916,-2.697856726640414,0.38894919874105743 3430
Metatarsus adductus 6 13 1.9605213438284703 0.0499348857703383 O96028,Q15392,O95202,P08236,Q96L58,Q9UBM7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 191,34,383,246,215,154 383,191,246,1650,1817,441,1869,2797,34,215,1047,154,2974 0.9163495326117879,1.6052450348577447,1.338473936006947,-0.11734646334023954,-0.18826843715602568,0.8084416390325024,-0.2120155691768394,-0.6242916466860307,3.583187167896173,1.4828295622266432,0.18465877239643577,1.826640669391119,-0.7237852836123975 3430
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