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term	overlap	setsize	score	pval	edge	type	subtype	subtype_key	edge_idxs	ann_idxs	ann_vals	sig_size
Lysosome	25	51	4.697899573124127	2.628506108770523e-06	P06280,P16278,Q14108,Q93050,Q8NCC3,P10253,P13473,P50897,P10619,O00462,Q15904,P04062,O75503,P11117,P04066,P15586,Q9UI12,Q9Y487,P17900,O15118,Q13510,O14773,P54802,P07602,P20645	Processes and pathways	KEGG Pathways	msigdb_kegg	255,5,6,265,10,269,161,38,40,180,182,56,57,69,319,198,341,358,221,96,101,108,109,113,251	473,180,543,1515,108,96,1454,1318,57,56,319,255,347,113,2649,1214,2617,269,40,69,1039,816,161,1634,198,5,221,251,3228,38,2501,109,1183,2502,2008,1535,1894,101,6,182,10,2602,265,877,1557,641,341,1566,3177,918,358	0.7656032541864601,1.5137692083085525,0.6671297810793578,0.006307474011367515,2.1474158808446684,2.2759315653971224,0.03437193328851483,0.11769676093724667,2.8563508480242543,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,0.17253621044918402,-0.5878385067985065,1.164537106940616,3.227809668601115,2.64250124049558,0.2805565672472788,0.4385882859122563,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,1.231854696356683,-1.4336660463047972,3.2574988008466623,-0.49448594888254555,2.1474158808446684,0.19974671831673846,-0.49448594888254555,-0.2236212584096826,0.006307474011367515,-0.16521660034488708,2.2395519580884713,4.383005400114565,1.5137692083085525,4.301006972369739,-0.5565443734227432,1.187074181061587,0.41257400595833643,0.006307474011367515,0.5920441322650274,1.0039634351651625,0.006307474011367515,-1.2539690378581203,0.38643153062342506,0.9806125526787869	3367
Anion transport	18	59	4.26769454118408	1.9750351205827243e-05	Q9Y277,P21796,P41440,Q15043,P51798,P80404,Q9HC21,P14174,Q9UHG3,Q9C0H2,P08183,P07602,P30825,Q9H2D1,Q9UBX3,P30536,P45880,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	166,34,167,263,71,234,107,237,48,80,146,113,85,86,91,124,29,125	2756,961,1454,645,1517,508,1873,545,753,995,1877,113,146,1091,3263,1215,1040,361,237,34,855,124,85,167,29,71,1590,553,2067,2236,234,1186,1223,1226,764,295,2188,263,1433,3206,660,2192,125,470,80,1791,86,1972,1561,107,2207,641,91,48,2483,677,166,1452,3137	-0.7148241860051961,0.3337574021162552,0.03437193328851483,0.5667757956444454,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.490236763907363,0.30722341578558393,-0.16521660034488708,2.110076974296961,1.7808852976154201,0.25375565145434276,-1.5816442855181783,0.17253621044918402,0.2805565672472788,0.9571562106244959,1.2762487791777117,3.2722740469256966,0.41257400595833643,1.9771403969263128,2.3834885282361222,1.6181799067894833,3.403217513344748,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.2530609609086133,-0.34234834725948426,1.2983027806935246,0.19974671831673846,0.17253621044918402,0.17253621044918402,0.490236763907363,1.0963292676298746,-0.31242291199836886,1.187074181061587,0.062290731757696595,-1.3611000187999303,0.5667757956444454,-0.31242291199836886,1.9578570786990497,0.7899351985641869,2.4539090139419626,-0.1074347923116181,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,-0.31242291199836886,0.5920441322650274,2.312045215706412,3.107165693020846,-0.4637180795900233,0.5667757956444454,1.6388066898289295,0.062290731757696595,-1.1836636419604167	3367
Vacuolar lumen	21	65	4.224395995981273	2.3958246046174025e-05	P06280,P16278,Q14108,Q9UM22,P10253,O00584,P13473,P50897,P10619,Q8NHP8,O00462,P04062,Q9H7Z7,P11117,P04066,P15586,P17900,Q13510,O14773,P54802,P07602	Localization	GO Cellular component	msigdb_gocc	255,5,6,13,269,153,161,38,40,49,180,56,65,69,319,198,221,101,108,109,113	180,625,153,543,108,1454,3182,56,319,255,347,1697,2170,113,2649,648,269,40,69,1757,1812,161,1634,198,5,221,2123,2581,1759,1366,3228,3229,2500,38,2868,1763,2501,1591,109,3013,3042,2008,2353,1333,1706,1224,481,101,6,2809,441,1965,49,1117,2471,2034,1442,877,1730,1503,65,3031,641,13,2823	1.5137692083085525,0.5920441322650274,1.7406977485275759,0.6671297810793578,2.1474158808446684,0.03437193328851483,-1.2894537744189682,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.07877373131780484,-0.31242291199836886,2.110076974296961,-0.6193116841420223,0.5667757956444454,1.164537106940616,3.227809668601115,2.64250124049558,-0.1074347923116181,-0.1362485904097433,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,-0.2826609847711293,-0.5565443734227432,-0.1074347923116181,0.09006522764362623,-1.4336660463047972,-1.4336660463047972,-0.49448594888254555,3.2574988008466623,-0.8120166279085533,-0.1074347923116181,-0.49448594888254555,-0.02190402285820215,2.1474158808446684,-0.977885243317303,-1.011660171259644,-0.2236212584096826,-0.40269627647094874,0.11769676093724667,-0.07877373131780484,0.17253621044918402,0.7656032541864601,2.2395519580884713,4.383005400114565,-0.7470323872777213,0.8382620619356581,-0.19434031752410985,3.045680587864037,0.25375565145434276,-0.4637180795900233,-0.2236212584096826,0.062290731757696595,0.41257400595833643,-0.07877373131780484,0.03437193328851483,2.742374563169135,-0.977885243317303,0.5920441322650274,4.144687074033624,-0.7470323872777213	3367
Intrinsic component of plasma membrane	32	72	3.895212518815101	9.81126677614963e-05	Q15043,Q8WTV0,Q86UP2,Q9UJS0,P04439,O60637,P02786,P27105,P35613,P05067,P41440,O43657,O00264,Q8N2K0,Q99996,P53985,P16615,Q9Y4G8,Q9NR28,Q99808,Q92542,P30825,Q9H0U3,O96005,Q13641,Q9UIQ6,P10321,O15118,P01889,P51572,P20645,O00560	Localization	GO Cellular component	msigdb_gocc	263,9,397,677,389,24,529,157,286,160,167,53,304,442,184,553,305,59,196,470,218,85,622,220,607,228,229,96,598,238,251,625	680,304,625,2530,1685,782,96,1037,53,2220,24,2576,220,598,529,389,1213,160,995,1877,229,1215,1039,816,1040,305,1042,927,251,157,1217,85,2707,286,2291,167,238,553,792,2236,1186,1223,3046,975,1833,1378,607,263,2411,1433,2021,397,442,2957,1293,9,218,804,1069,470,184,987,1556,622,1308,196,2321,228,677,1623,678,59	0.5413858311413456,1.0503522207387042,0.5920441322650274,-0.525427454868466,-0.07877373131780484,0.46447550012638145,2.2759315653971224,0.2805565672472788,2.9519476787527323,-0.34234834725948426,3.5306255572552185,-0.5565443734227432,1.3639014130956277,0.6171918880980484,0.6919219483408452,0.9099236880488443,0.17253621044918402,1.7001874873242686,0.30722341578558393,-0.16521660034488708,1.3202624041063196,0.17253621044918402,0.2805565672472788,0.4385882859122563,0.2805565672472788,1.0503522207387042,0.2805565672472788,0.3601597156898264,1.231854696356683,1.7204832487252557,0.17253621044918402,2.3834885282361222,-0.6509657620201212,1.1191654406700127,-0.3724389183184647,1.6181799067894833,1.2762487791777117,0.6671297810793578,0.46447550012638145,-0.34234834725948426,0.19974671831673846,0.17253621044918402,-1.011660171259644,0.3337574021162552,-0.1362485904097433,0.09006522764362623,0.6171918880980484,1.187074181061587,-0.4331220969912666,0.062290731757696595,-0.2236212584096826,0.9099236880488443,0.8382620619356581,-0.9109430815275097,0.1451866537146581,4.324586732934785,1.3855822269020739,0.46447550012638145,0.2805565672472788,0.7899351985641869,1.5137692083085525,0.3337574021162552,0.006307474011367515,0.6171918880980484,0.1451866537146581,1.471397176367932,-0.3724389183184647,1.3421283755465698,0.5667757956444454,-0.02190402285820215,0.5667757956444454,2.840232108692598	3367
Lysosomal lumen	20	36	3.884404461668846	0.0001025810192447	P06280,P16278,Q14108,Q9UM22,P10253,O00584,P13473,P50897,P10619,Q8NHP8,O00462,P04062,P11117,P04066,P15586,P17900,Q13510,O14773,P54802,P07602	Localization	GO Cellular component	msigdb_gocc	255,5,6,13,269,153,161,38,40,49,180,56,69,319,198,221,101,108,109,113	180,153,543,108,1454,56,319,255,347,113,2649,648,269,40,69,1757,161,1634,198,5,221,1366,3228,3229,38,109,2008,101,6,441,1965,49,877,1503,641,13	1.5137692083085525,1.7406977485275759,0.6671297810793578,2.1474158808446684,0.03437193328851483,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,0.5667757956444454,1.164537106940616,3.227809668601115,2.64250124049558,-0.1074347923116181,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,0.09006522764362623,-1.4336660463047972,-1.4336660463047972,3.2574988008466623,2.1474158808446684,-0.2236212584096826,2.2395519580884713,4.383005400114565,0.8382620619356581,-0.19434031752410985,3.045680587864037,0.41257400595833643,0.03437193328851483,0.5920441322650274,4.144687074033624	3367
Corneal opacity	23	58	3.877413815337564	0.0001055727070295	P51648,P06280,Q92889,P16278,Q06136,P56589,P10619,P52732,Q9NZC9,P34913,P04062,Q9UBM7,Q16625,O75844,P04066,Q9Y4P3,O43505,O95202,O43933,Q13510,O96028,Q9NVI7,P53701	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	128,255,520,5,142,533,40,421,447,181,56,185,188,68,319,344,87,330,92,101,236,503,363	543,1170,782,87,1084,3094,2573,92,1458,3004,713,2648,68,1875,330,236,1522,56,319,255,1461,40,5,898,650,181,2539,900,2347,128,421,363,2178,533,1472,1707,973,142,2072,2953,101,1103,1652,1901,2775,188,660,3218,1847,520,3026,503,1129,447,185,1743,2042,344	0.6671297810793578,0.19974671831673846,0.46447550012638145,2.3478963961729225,0.25375565145434276,-1.1142272342228774,-0.5565443734227432,2.294021415669942,0.03437193328851483,-0.977885243317303,0.5158731784643796,-0.6193116841420223,2.6926945390869426,-0.16521660034488708,1.0039634351651625,1.2762487791777117,0.006307474011367515,2.888427682882454,1.0272097103903832,1.2095131214680288,0.03437193328851483,3.227809668601115,4.4292036485047825,0.38643153062342506,0.5667757956444454,1.5137692083085525,-0.525427454868466,0.38643153062342506,-0.40269627647094874,1.9384991366690936,0.862258844628111,0.9571562106244959,-0.31242291199836886,0.6919219483408452,0.03437193328851483,-0.07877373131780484,0.3337574021162552,1.820754742930303,-0.2530609609086133,-0.9109430815275097,2.2395519580884713,0.25375565145434276,-0.050263952997597124,-0.16521660034488708,-0.7148241860051961,1.4926272539284748,0.5667757956444454,-1.3972667312364715,-0.1362485904097433,0.7165975954483155,-0.977885243317303,0.7411577066416265,0.25375565145434276,0.8382620619356581,1.5137692083085525,-0.07877373131780484,-0.2236212584096826,1.0039634351651625	3367
Inorganic molecular entity transmembrane transporter activity	20	57	3.847003256332257	0.0001195713808237	Q15043,Q93050,O75964,Q13423,P45880,Q9Y277,P21796,Q9HD20,P16615,P51798,P13073,Q9UI12,Q9C0H2,P56385,O95202,Q9Y487,Q9UBX3,Q6P4Q7,Q9UDW1,P06576	Functions	GO Molecular function	msigdb_gomf	263,265,17,278,29,166,34,165,305,71,73,341,80,214,330,358,91,369,112,250	2756,1454,851,17,330,718,1213,995,250,1697,1810,1091,1756,3263,2060,1040,73,305,927,819,548,2897,34,378,1580,3193,759,970,2498,29,1889,2928,71,2236,2296,214,2502,2237,1186,1223,278,263,3206,369,1604,698,265,80,622,1972,165,91,112,341,166,358,3137	-0.7148241860051961,0.03437193328851483,0.41257400595833643,3.867353512797234,1.0039634351651625,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,0.2805565672472788,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,3.2722740469256966,0.9335935466195544,-0.02190402285820215,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,3.403217513344748,-0.16521660034488708,-0.8777714879158465,2.6256544201008225,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.1419011221151822,1.187074181061587,-1.3611000187999303,0.9571562106244959,-0.02190402285820215,0.5413858311413456,1.187074181061587,2.4539090139419626,0.6171918880980484,-0.19434031752410985,1.6388066898289295,2.312045215706412,2.1287815015903986,1.0039634351651625,1.6388066898289295,0.9806125526787869,-1.1836636419604167	3367
Ion transmembrane transporter activity	39	80	3.739587339706999	0.0001843225974211	P24539,Q15043,Q93050,O75746,Q9UJS0,O75964,Q13423,P45880,Q6NUK1,P21796,Q9Y277,Q9HD20,P41440,O43808,O43772,O95563,P21281,P53985,P16615,Q9BVC6,P51798,P13073,Q70HW3,Q9UI12,Q9C0H2,P56385,Q99808,P30825,Q9H2D1,O95202,Q9H0U3,Q9Y487,Q9UBX3,Q9HC21,Q6P4Q7,Q9UDW1,P12236,P06576,Q8TB61	Functions	GO Molecular function	msigdb_gomf	378,263,265,508,677,17,278,29,660,34,166,165,167,645,169,545,548,553,305,591,71,73,77,341,80,214,470,85,86,330,622,358,91,107,369,112,361,250,125	2756,961,1454,169,645,508,851,17,330,545,718,1213,995,250,1697,1810,1091,1756,3263,2060,1215,1040,361,73,305,927,819,548,2897,34,378,1580,85,3193,759,970,2498,167,29,1889,2928,71,1590,553,2236,2296,214,2502,2237,1186,1223,278,1839,263,1433,3206,660,2192,369,77,1604,125,698,265,470,591,80,622,86,1972,1561,107,165,91,112,341,677,166,358,3137	-0.7148241860051961,0.3337574021162552,0.03437193328851483,1.5974688426783576,0.5667757956444454,0.7165975954483155,0.41257400595833643,3.867353512797234,1.0039634351651625,0.6671297810793578,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,0.17253621044918402,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,3.2722740469256966,0.9335935466195544,-0.02190402285820215,2.3834885282361222,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,1.6181799067894833,3.403217513344748,-0.16521660034488708,-0.8777714879158465,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.1419011221151822,-0.1362485904097433,1.187074181061587,0.062290731757696595,-1.3611000187999303,0.5667757956444454,-0.31242291199836886,0.9571562106244959,2.5060688955133497,-0.02190402285820215,1.9578570786990497,0.5413858311413456,1.187074181061587,0.7899351985641869,0.6422200972561323,2.4539090139419626,0.6171918880980484,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,2.312045215706412,2.1287815015903986,1.0039634351651625,0.5667757956444454,1.6388066898289295,0.9806125526787869,-1.1836636419604167	3367
Membrane lipid metabolic process	17	35	3.689853311686482	0.0002243833984314	Q9H490,Q99735,P06280,P06865,P16278,P50897,P04066,Q13510,Q8NCC3,Q96G23,Q06136,P07602,Q8NBX0,P04062,Q53H12,O95470,P17900	Processes and pathways	GO Biological process	msigdb_gobp	261,260,255,347,5,38,319,101,10,43,142,113,116,56,440,123,221	448,1317,1572,123,56,319,255,347,113,2649,5,221,2002,756,1218,38,1224,142,1226,101,440,116,10,2312,1969,43,667,260,1069,261,1204,1406,641,704,1979	0.8141544886580385,0.11769676093724667,-0.02190402285820215,1.9771403969263128,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,4.4292036485047825,1.3639014130956277,-0.2236212584096826,0.490236763907363,0.17253621044918402,3.2574988008466623,0.17253621044918402,1.820754742930303,0.17253621044918402,2.2395519580884713,0.8382620619356581,2.072455559506005,4.301006972369739,-0.3724389183184647,-0.19434031752410985,3.1829254312869844,0.5667757956444454,1.2095131214680288,0.2805565672472788,1.2095131214680288,0.19974671831673846,0.09006522764362623,0.5920441322650274,0.5413858311413456,-0.19434031752410985	3367
Mitochondrial transmembrane transport	17	45	3.602996784147457	0.0003145694219419	P24539,Q99595,O95202,P21796,O14925,O43772,P23786,Q9UJZ1,O60830,O75964,P56385,Q9BSK2,P12236,Q9H2D1,Q8IYU8,O75027,P06576	Processes and pathways	GO Biological process	msigdb_gobp	378,37,330,34,262,169,207,317,47,17,214,314,361,86,150,211,250	262,376,169,47,211,2647,508,851,17,2761,330,545,716,1361,995,250,1999,1040,361,34,207,378,1580,759,2928,1181,1590,2296,214,1186,2018,150,1604,2310,1196,37,948,314,86,1972,1561,1307,677,317,1133	1.187074181061587,0.9335935466195544,1.5974688426783576,3.107165693020846,1.3855822269020739,-0.6193116841420223,0.7165975954483155,0.41257400595833643,3.867353512797234,-0.7148241860051961,1.0039634351651625,0.6671297810793578,0.5158731784643796,0.09006522764362623,0.30722341578558393,1.231854696356683,-0.2236212584096826,0.2805565672472788,0.9571562106244959,3.2722740469256966,1.4286699849010147,0.9335935466195544,-0.02190402285820215,0.490236763907363,-0.8777714879158465,0.19974671831673846,-0.02190402285820215,-0.3724389183184647,1.3855822269020739,0.19974671831673846,-0.2236212584096826,1.7608315718187155,-0.02190402285820215,-0.3724389183184647,0.19974671831673846,3.2722740469256966,0.3601597156898264,1.0503522207387042,2.3657246319376566,-0.19434031752410985,0.006307474011367515,0.1451866537146581,0.5667757956444454,1.0503522207387042,0.25375565145434276	3367
Steroid binding	7	22	3.594626799805559	0.0003248569024294	O15118,P21796,Q14108,O15173,P04062,P45880,Q14849	Functions	GO Molecular function	msigdb_gomf	96,34,6,118,56,29,31	304,96,118,1808,56,1213,1810,34,2002,2579,124,1046,1366,29,2008,6,31,1241,2479,400,880,1245	1.0503522207387042,2.2759315653971224,2.0535377021037875,-0.1362485904097433,2.888427682882454,0.17253621044918402,-0.1362485904097433,3.2722740469256966,-0.2236212584096826,-0.5565443734227432,1.9771403969263128,0.2805565672472788,0.09006522764362623,3.403217513344748,-0.2236212584096826,4.383005400114565,3.3454673481684774,0.17253621044918402,-0.4637180795900233,0.9099236880488443,0.41257400595833643,0.17253621044918402	3367
Intrinsic component of endoplasmic reticulum membrane	20	48	3.566929290581605	0.0003611888899817	Q9H490,Q86UP2,Q15629,P57088,P04439,Q15041,Q9BUN8,Q15125,Q9UBM7,O75844,Q8TCT9,Q9Y4P3,Q9Y282,P10321,Q9NQC3,P51572,Q86XL3,O95470,Q99442,Q8TB61	Localization	GO Cellular component	msigdb_gocc	261,397,11,393,389,295,301,177,185,68,201,344,84,229,106,238,111,123,383,125	680,1083,2328,963,68,628,123,598,389,229,2538,1217,1044,238,393,2237,795,1838,1480,295,177,11,2307,905,397,111,484,1547,125,201,2312,1969,431,667,383,3256,301,261,1674,106,2427,1406,704,2521,185,84,344,2113	0.5413858311413456,0.25375565145434276,-0.40269627647094874,0.3337574021162552,2.6926945390869426,0.5920441322650274,1.9771403969263128,0.6171918880980484,0.9099236880488443,1.3202624041063196,-0.525427454868466,0.17253621044918402,0.2805565672472788,1.2762487791777117,0.9099236880488443,-0.34234834725948426,0.46447550012638145,-0.1362485904097433,0.03437193328851483,1.0963292676298746,1.5348236972160396,4.156903668614397,-0.3724389183184647,0.38643153062342506,0.9099236880488443,2.1287815015903986,0.7656032541864601,0.006307474011367515,1.9578570786990497,1.450078310745009,-0.3724389183184647,-0.19434031752410985,0.862258844628111,0.5667757956444454,0.9335935466195544,-1.507173381664675,1.07339179882247,1.2095131214680288,-0.050263952997597124,2.1844760833621826,-0.4331220969912666,0.09006522764362623,0.5413858311413456,-0.49448594888254555,1.5137692083085525,2.401188502744234,1.0039634351651625,-0.2530609609086133	3367
Anion transmembrane transport	11	35	3.566330248137737	0.0003620151194976	Q9Y277,P21796,P51798,Q9HC21,Q9UHG3,P08183,P30825,Q9H2D1,Q9UBX3,P45880,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	166,34,71,107,48,146,85,86,91,29,125	645,1517,508,1873,545,995,1877,146,1091,1040,361,34,85,167,29,71,1590,553,2236,1186,1223,764,295,1433,125,86,1972,1561,107,2207,91,48,677,166,1452	0.5667757956444454,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.30722341578558393,-0.16521660034488708,1.7808852976154201,0.25375565145434276,0.2805565672472788,0.9571562106244959,3.2722740469256966,2.3834885282361222,1.6181799067894833,3.403217513344748,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,0.19974671831673846,0.17253621044918402,0.490236763907363,1.0963292676298746,0.062290731757696595,1.9578570786990497,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,-0.31242291199836886,2.312045215706412,3.107165693020846,0.5667757956444454,1.6388066898289295,0.062290731757696595	3367
Intrinsic component of organelle membrane	57	111	3.5657372936159657	0.0003628346924171	Q9H490,Q16891,O95070,Q9H3K2,O14925,Q96S52,Q86UP2,Q15629,P57088,P04439,Q9BUR5,P56589,Q9Y2R0,Q10471,P13473,Q14739,Q99595,P42892,Q96A33,O43808,Q15041,Q9P035,Q9BUN8,O60830,O95563,Q15125,Q9NX63,Q9UBM7,Q53H12,O75844,Q8TCT9,Q86Y82,Q5XKP0,Q6ZRP7,Q9Y4P3,O43752,Q9Y282,O43505,Q13505,Q86YN1,O15118,P10321,O75880,P01889,O15258,Q9NQC3,Q9HC21,Q86XL3,P51572,Q9Y512,Q15070,Q5SNT2,Q6UXV4,O95470,Q99442,Q8TB61,O76024	Localization	GO Cellular component	msigdb_gocc	261,381,377,672,262,667,397,11,393,389,412,533,26,654,161,289,37,35,431,645,295,704,301,47,545,177,316,185,440,68,201,459,581,457,344,206,84,87,99,484,96,229,597,598,475,106,107,111,238,644,366,382,121,123,383,125,628	680,3092,1083,262,2328,96,475,963,87,206,645,1455,47,2331,68,597,628,2761,752,377,123,545,1361,598,389,229,1040,161,927,1758,2538,1217,1044,3143,35,1181,2235,238,533,393,2237,1186,654,795,99,1838,289,1480,295,366,177,2247,11,767,381,440,2307,382,581,905,121,457,397,111,459,484,1289,2811,2632,1547,1604,125,201,1392,2312,1969,431,667,383,37,948,3256,808,301,412,1555,672,261,1561,2480,107,1674,106,1509,1310,316,2427,1406,704,2521,185,742,1251,1622,84,26,3053,344,1133,644,2113	0.5413858311413456,-1.1142272342228774,0.25375565145434276,1.187074181061587,-0.40269627647094874,2.2759315653971224,0.7656032541864601,0.3337574021162552,2.3478963961729225,1.4286699849010147,0.5667757956444454,0.03437193328851483,3.107165693020846,-0.40269627647094874,2.6926945390869426,0.6171918880980484,0.5920441322650274,-0.7148241860051961,0.490236763907363,0.9335935466195544,1.9771403969263128,0.6671297810793578,0.09006522764362623,0.6171918880980484,0.9099236880488443,1.3202624041063196,0.2805565672472788,1.679809873082842,0.3601597156898264,-0.1074347923116181,-0.525427454868466,0.17253621044918402,0.2805565672472788,-1.2187064928309388,3.2722740469256966,0.19974671831673846,-0.34234834725948426,1.2762487791777117,0.6919219483408452,0.9099236880488443,-0.34234834725948426,0.19974671831673846,0.5667757956444454,0.46447550012638145,2.2759315653971224,-0.1362485904097433,1.1191654406700127,0.03437193328851483,1.0963292676298746,0.9571562106244959,1.5348236972160396,-0.34234834725948426,4.156903668614397,0.490236763907363,0.9335935466195544,0.8382620619356581,-0.3724389183184647,0.9335935466195544,0.6422200972561323,0.38643153062342506,2.0154852262905982,0.8141544886580385,0.9099236880488443,2.1287815015903986,0.8141544886580385,0.7656032541864601,0.1451866537146581,-0.7470323872777213,-0.5878385067985065,0.006307474011367515,-0.02190402285820215,1.9578570786990497,1.450078310745009,0.09006522764362623,-0.3724389183184647,-0.19434031752410985,0.862258844628111,0.5667757956444454,0.9335935466195544,3.2722740469256966,0.3601597156898264,-1.507173381664675,0.46447550012638145,1.07339179882247,0.8861457519054411,0.006307474011367515,0.5667757956444454,1.2095131214680288,0.006307474011367515,-0.4637180795900233,2.165980585241542,-0.050263952997597124,2.1844760833621826,0.03437193328851483,0.1451866537146581,1.0503522207387042,-0.4331220969912666,0.09006522764362623,0.5413858311413456,-0.49448594888254555,1.5137692083085525,0.5158731784643796,0.17253621044918402,-0.02190402285820215,2.401188502744234,3.5306255572552185,-1.011660171259644,1.0039634351651625,0.25375565145434276,0.5920441322650274,-0.2530609609086133	3367
Cation transmembrane transporter activity	18	53	3.5444570269055258	0.000393422632237	Q9HD20,Q15043,Q9Y487,Q93050,O43772,P13073,Q9HC21,Q70HW3,Q9UI12,Q6P4Q7,Q9UDW1,O75964,P56385,P30825,O95202,Q13423,P06576,P16615	Functions	GO Molecular function	msigdb_gomf	165,263,358,265,169,73,107,77,341,369,112,17,214,85,330,278,250,305	169,645,851,17,330,718,1213,995,250,1697,1810,1091,1756,2060,1040,73,305,927,819,548,2897,378,1580,85,3193,759,970,2498,1889,2928,2236,2296,214,2502,2237,1186,278,263,1433,369,77,1604,698,265,470,622,1972,1561,107,165,112,341,358	1.5974688426783576,0.5667757956444454,0.41257400595833643,3.867353512797234,1.0039634351651625,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-0.2530609609086133,0.2805565672472788,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,0.9335935466195544,-0.02190402285820215,2.3834885282361222,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,-0.16521660034488708,-0.8777714879158465,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.19974671831673846,1.1419011221151822,1.187074181061587,0.062290731757696595,0.9571562106244959,2.5060688955133497,-0.02190402285820215,0.5413858311413456,1.187074181061587,0.7899351985641869,0.6171918880980484,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,2.1287815015903986,1.0039634351651625,0.9806125526787869	3367
Sphingolipid metabolic process	13	27	3.490855642185042	0.0004814763284428	P06280,P06865,P16278,P50897,Q13510,Q8NCC3,Q96G23,Q06136,P07602,P04062,Q53H12,O95470,P17900	Processes and pathways	GO Biological process	msigdb_gobp	255,347,5,38,101,10,43,142,113,56,440,123,221	448,1317,123,56,255,347,113,2649,5,221,2002,756,1218,38,1224,142,1226,101,440,10,43,1069,1204,1406,641,704,1979	0.8141544886580385,0.11769676093724667,1.9771403969263128,2.888427682882454,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,4.4292036485047825,1.3639014130956277,-0.2236212584096826,0.490236763907363,0.17253621044918402,3.2574988008466623,0.17253621044918402,1.820754742930303,0.17253621044918402,2.2395519580884713,0.8382620619356581,4.301006972369739,3.1829254312869844,0.2805565672472788,0.19974671831673846,0.09006522764362623,0.5920441322650274,0.5413858311413456,-0.19434031752410985	3367
Azurophil granule	19	68	3.471930434085495	0.0005167302199509	P06280,P16278,P10253,P42785,O00584,P27105,P13473,P10619,O00462,O15260,Q9H7Z7,P04066,P15586,Q92542,P17900,P06865,P07602,Q07065,O95721	Localization	GO Cellular component	msigdb_gocc	255,5,269,18,153,157,161,40,180,60,65,319,198,218,221,347,113,120,122	180,625,153,543,60,626,1454,2489,2052,122,3182,319,255,347,1697,2170,113,2649,269,40,1812,1039,161,1634,198,5,221,2123,157,2581,1759,2228,18,2500,2868,1822,1182,1763,2501,1591,3013,3042,2008,2353,1333,1706,1224,120,481,2809,380,769,1965,1342,218,1117,2554,2471,2034,1442,3117,1730,622,65,3031,641,1979,2823	1.5137692083085525,0.5920441322650274,1.7406977485275759,0.6671297810793578,2.775214074894696,0.5920441322650274,0.03437193328851483,-0.49448594888254555,-0.2530609609086133,1.9963496087227715,-1.2894537744189682,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.07877373131780484,-0.31242291199836886,2.110076974296961,-0.6193116841420223,1.164537106940616,3.227809668601115,-0.1362485904097433,0.2805565672472788,1.679809873082842,-0.050263952997597124,1.450078310745009,4.4292036485047825,1.3639014130956277,-0.2826609847711293,1.7204832487252557,-0.5565443734227432,-0.1074347923116181,-0.34234834725948426,3.8282095648532786,-0.49448594888254555,-0.8120166279085533,-0.1362485904097433,0.19974671831673846,-0.1074347923116181,-0.49448594888254555,-0.02190402285820215,-0.977885243317303,-1.011660171259644,-0.2236212584096826,-0.40269627647094874,0.11769676093724667,-0.07877373131780484,0.17253621044918402,2.0154852262905982,0.7656032541864601,-0.7470323872777213,0.9335935466195544,0.490236763907363,-0.19434031752410985,0.11769676093724667,1.3855822269020739,0.25375565145434276,-0.525427454868466,-0.4637180795900233,-0.2236212584096826,0.062290731757696595,-1.1488380282478365,-0.07877373131780484,0.6171918880980484,2.742374563169135,-0.977885243317303,0.5920441322650274,-0.19434031752410985,-0.7470323872777213	3367
Mitochondrial transport	34	77	3.4408111662790084	0.0005799731394726	Q9NS69,P24539,O43615,O14925,P49840,Q9UJS0,O75964,O00170,P07900,P45880,Q14849,P48506,Q5JRX3,Q10713,Q99595,O43772,O60830,Q9UJZ1,Q96EK5,Q53H12,Q9Y276,P23786,O14737,P56385,Q9UBX3,P55786,P04637,P51572,Q9P0J0,Q9Y512,Q15070,P49257,P06576,P30536	Processes and pathways	GO Biological process	msigdb_gobp	0,378,376,262,512,677,17,268,648,29,31,287,658,655,37,169,47,317,444,440,342,207,205,214,91,93,479,238,386,644,366,496,250,124	268,205,262,376,169,47,2331,2647,851,17,2761,2860,2732,2056,716,1361,479,995,250,648,2337,1999,1040,2226,207,378,1580,3240,2290,124,1934,759,2769,29,2928,287,496,512,2234,1181,238,2446,93,2296,214,2739,655,1226,31,366,1189,2018,440,658,660,1488,2811,2632,1196,444,1344,1123,37,2102,1307,1509,0,386,2566,91,677,317,342,2887,1624,644,2755	1.164537106940616,1.4286699849010147,1.187074181061587,0.9335935466195544,1.5974688426783576,3.107165693020846,-0.40269627647094874,-0.6193116841420223,0.41257400595833643,3.867353512797234,-0.7148241860051961,-0.8120166279085533,-0.682802624960496,-0.2530609609086133,0.5158731784643796,0.09006522764362623,0.7656032541864601,0.30722341578558393,1.231854696356683,0.5667757956444454,-0.40269627647094874,-0.2236212584096826,0.2805565672472788,-0.34234834725948426,1.4286699849010147,0.9335935466195544,-0.02190402285820215,-1.4703006768417601,-0.3724389183184647,1.9771403969263128,-0.19434031752410985,0.490236763907363,-0.7148241860051961,3.403217513344748,-0.8777714879158465,1.1191654406700127,0.7411577066416265,0.7165975954483155,-0.34234834725948426,0.19974671831673846,1.2762487791777117,-0.4637180795900233,2.294021415669942,-0.3724389183184647,1.3855822269020739,-0.682802624960496,0.5667757956444454,0.17253621044918402,3.3454673481684774,0.9571562106244959,0.19974671831673846,-0.2236212584096826,0.8382620619356581,0.5667757956444454,0.5667757956444454,0.03437193328851483,-0.7470323872777213,-0.5878385067985065,0.19974671831673846,0.8382620619356581,0.11769676093724667,0.25375565145434276,3.2722740469256966,-0.2530609609086133,0.1451866537146581,0.03437193328851483,4.803828948758111,0.9335935466195544,-0.525427454868466,2.312045215706412,0.5667757956444454,1.0503522207387042,1.0039634351651625,-0.8120166279085533,-0.02190402285820215,0.5920441322650274,-0.682802624960496	3367
Metal ion homeostasis	26	71	3.42408605217662	0.0006168708420044	Q96PU5,Q15043,P30519,P09601,Q8IYU8,P05067,Q96A33,Q9HD20,P09429,Q9UJZ1,Q96TC7,Q15904,Q658P3,P16615,P78417,Q8NE01,O60826,O95202,Q9Y487,O75027,Q8N511,P62942,O00203,Q6P4Q7,P51572,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	521,263,16,21,150,160,431,165,417,317,313,182,189,305,72,335,329,330,358,211,90,97,473,369,238,381	473,1515,1455,2118,329,211,597,1359,628,330,1753,529,2922,1212,1213,160,2649,1810,417,21,817,1418,305,818,927,1141,3140,2538,969,16,3125,2498,999,238,792,2236,2502,1098,97,72,1947,3101,2013,2981,1227,263,2411,182,381,189,369,1011,1490,150,90,335,1604,1292,1196,431,2603,521,313,948,1126,165,317,1623,358,1133,844	0.7656032541864601,0.006307474011367515,0.03437193328851483,-0.2826609847711293,1.0039634351651625,1.3855822269020739,0.6171918880980484,0.09006522764362623,0.5920441322650274,1.0039634351651625,-0.1074347923116181,0.6919219483408452,-0.8777714879158465,0.17253621044918402,0.17253621044918402,1.7001874873242686,-0.6193116841420223,-0.1362485904097433,0.862258844628111,3.613683844728898,0.4385882859122563,0.062290731757696595,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.22681944749468783,-1.2187064928309388,-0.525427454868466,0.3337574021162552,3.9318663108151224,-1.1836636419604167,-0.49448594888254555,0.30722341578558393,1.2762487791777117,0.46447550012638145,-0.34234834725948426,-0.49448594888254555,0.25375565145434276,2.2759315653971224,2.59178502036956,-0.19434031752410985,-1.1142272342228774,-0.2236212584096826,-0.9443136123937819,0.17253621044918402,1.187074181061587,-0.4331220969912666,1.5137692083085525,0.9335935466195544,1.4926272539284748,0.9571562106244959,0.30722341578558393,0.03437193328851483,1.7608315718187155,2.33000339930892,1.0039634351651625,-0.02190402285820215,0.1451866537146581,0.19974671831673846,0.862258844628111,-0.5565443734227432,0.7165975954483155,1.0503522207387042,0.3601597156898264,0.25375565145434276,1.6388066898289295,1.0503522207387042,-0.02190402285820215,0.9806125526787869,0.25375565145434276,0.4385882859122563	3367
Receptor	13	35	3.3686150836099618	0.000755468510067	Q9NS69,Q14739,P24390,Q5KU26,O15118,Q14108,Q8WTV0,Q99720,Q99623,P30825,O15173,P20645,P35613	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	0,289,2,193,96,6,9,20,282,85,118,251,286	304,2530,1685,96,118,529,1877,720,1929,2828,1880,1039,816,1930,251,2,85,286,422,3046,1378,6,1103,289,1433,193,9,698,282,20,0,705,490,891,2968	1.0503522207387042,-0.525427454868466,-0.07877373131780484,2.2759315653971224,2.0535377021037875,0.6919219483408452,-0.16521660034488708,0.5158731784643796,-0.19434031752410985,-0.7794292005641262,-0.16521660034488708,0.2805565672472788,0.4385882859122563,-0.19434031752410985,1.231854696356683,4.631429349052777,2.3834885282361222,1.1191654406700127,0.862258844628111,-1.011660171259644,0.09006522764362623,4.383005400114565,0.25375565145434276,1.1191654406700127,0.062290731757696595,1.471397176367932,4.324586732934785,0.5413858311413456,1.1419011221151822,3.641045663369028,4.803828948758111,0.5413858311413456,0.7656032541864601,0.41257400595833643,-0.9109430815275097	3367
SLC superfamily of solute carriers	22	38	3.317567858405514	0.0009080485520625	Q15043,O75746,Q9UJS0,Q6NUK1,P41440,O43772,O95563,Q6NT16,Q9BSK2,P53985,Q8IXU6,Q70HW3,Q99808,P30825,Q9H2D1,O95202,Q9H0U3,Q9UBX3,Q9HC21,P12236,Q9NZJ7,Q8TB61	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	263,508,677,660,167,169,545,178,314,553,70,77,470,85,86,330,622,91,107,361,641,125	2328,169,645,508,330,545,995,1091,1215,1040,361,85,167,1590,553,2236,1186,1223,263,1433,3206,178,660,2192,77,70,125,470,314,622,86,1972,1561,107,641,91,677,919	-0.40269627647094874,1.5974688426783576,0.5667757956444454,0.7165975954483155,1.0039634351651625,0.6671297810793578,0.30722341578558393,0.25375565145434276,0.17253621044918402,0.2805565672472788,0.9571562106244959,2.3834885282361222,1.6181799067894833,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.187074181061587,0.062290731757696595,-1.3611000187999303,1.5348236972160396,0.5667757956444454,-0.31242291199836886,2.5060688955133497,2.64250124049558,1.9578570786990497,0.7899351985641869,1.0503522207387042,0.6171918880980484,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,0.5920441322650274,2.312045215706412,0.5667757956444454,0.38643153062342506	3367
Endoplasmic reticulum golgi intermediate compartment	22	45	3.283163712315535	0.0010264903463403	P80303,P24390,O95070,P49755,Q8IUR0,P09429,Q02818,Q15904,Q10472,O15260,Q9Y3B3,Q9Y282,Q15084,Q8N511,P30533,O15258,P07237,P51572,Q13190,Q9BVK6,Q08379,P49257	Localization	GO Cellular component	msigdb_gocc	1,2,377,511,159,417,54,182,308,60,219,84,483,90,225,475,599,238,365,640,497,496	475,60,1037,963,1807,377,599,417,2,2538,225,496,511,1096,238,2835,2501,1591,1,54,497,308,975,365,1479,483,182,1107,159,90,1722,3105,3255,875,1023,640,669,1739,2641,1680,1079,84,219,1082,1684	0.7656032541864601,2.775214074894696,0.2805565672472788,0.3337574021162552,-0.1362485904097433,0.9335935466195544,0.6171918880980484,0.862258844628111,4.631429349052777,-0.525427454868466,1.3421283755465698,0.7411577066416265,0.7165975954483155,0.25375565145434276,1.2762487791777117,-0.7794292005641262,-0.49448594888254555,-0.02190402285820215,4.739957488800412,2.9519476787527323,0.7411577066416265,1.0503522207387042,0.3337574021162552,0.9571562106244959,0.03437193328851483,0.7656032541864601,1.5137692083085525,0.25375565145434276,1.7204832487252557,2.33000339930892,-0.07877373131780484,-1.1142272342228774,-1.507173381664675,0.41257400595833643,0.30722341578558393,0.5920441322650274,0.5667757956444454,-0.07877373131780484,-0.5878385067985065,-0.050263952997597124,0.2805565672472788,2.401188502744234,1.3855822269020739,0.2805565672472788,-0.050263952997597124	3367
Sphingolipid metabolism	11	25	3.2769277467048883	0.0010494322061453	P51648,P06280,P16278,Q13510,P10619,Q96G23,Q06136,P07602,P04062,O95470,P17900	Processes and pathways	Reactome Pathways	msigdb_reactome	128,255,5,101,40,43,142,113,56,123,221	680,448,1317,1454,1753,123,56,255,347,113,2649,40,1634,5,221,2002,756,128,142,101,43,3256,1204,641,1979	0.5413858311413456,0.8141544886580385,0.11769676093724667,0.03437193328851483,-0.1074347923116181,1.9771403969263128,2.888427682882454,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,3.227809668601115,-0.050263952997597124,4.4292036485047825,1.3639014130956277,-0.2236212584096826,0.490236763907363,1.9384991366690936,1.820754742930303,2.2395519580884713,3.1829254312869844,-1.507173381664675,0.19974671831673846,0.5920441322650274,-0.19434031752410985	3367
Inner mitochondrial membrane protein complex	24	69	3.253827219774052	0.0011386150897041	P24539,O14925,P09669,O75964,O43676,Q9BUR5,Q99623,Q8IYU8,P14406,Q99595,O60830,Q9NX63,Q86Y39,P13073,Q9Y276,P56385,Q13505,Q9P0J0,Q9UDW1,P12236,Q6UXV4,P06576,Q16891,Q96CU9	Localization	GO Cellular component	msigdb_gocc	378,262,391,17,19,412,282,150,27,37,47,316,324,73,342,214,99,386,112,361,121,250,381,126	2645,1746,262,19,47,2758,2730,2331,1261,851,17,1876,3202,3054,2827,718,250,1756,391,2060,361,73,27,2701,2896,819,2001,2580,378,1580,3141,3142,3193,2707,759,3143,1889,2928,3265,762,2296,214,99,1840,1539,381,2018,440,581,121,324,150,1604,126,947,37,282,948,412,1307,1310,1129,316,386,112,342,1133,644,920	-0.6193116841420223,-0.1074347923116181,1.187074181061587,3.735568419211056,3.107165693020846,-0.7148241860051961,-0.682802624960496,-0.40269627647094874,0.1451866537146581,0.41257400595833643,3.867353512797234,-0.16521660034488708,-1.3611000187999303,-1.0456406280505959,-0.7794292005641262,0.5158731784643796,1.231854696356683,-0.1074347923116181,0.9099236880488443,-0.2530609609086133,0.9571562106244959,2.5747617035953736,3.4175453651007617,-0.6509657620201212,-0.8447967022235733,0.4385882859122563,-0.2236212584096826,-0.5565443734227432,0.9335935466195544,-0.02190402285820215,-1.2187064928309388,-1.2187064928309388,-1.3251632411413339,-0.6509657620201212,0.490236763907363,-1.2187064928309388,-0.16521660034488708,-0.8777714879158465,-1.5816442855181783,0.490236763907363,-0.3724389183184647,1.3855822269020739,2.2759315653971224,-0.1362485904097433,0.006307474011367515,0.9335935466195544,-0.2236212584096826,0.8382620619356581,0.6422200972561323,2.0154852262905982,1.0272097103903832,1.7608315718187155,-0.02190402285820215,1.9578570786990497,0.3601597156898264,3.2722740469256966,1.1419011221151822,0.3601597156898264,0.8861457519054411,0.1451866537146581,0.1451866537146581,0.25375565145434276,1.0503522207387042,0.9335935466195544,2.1287815015903986,1.0039634351651625,0.25375565145434276,0.5920441322650274,0.38643153062342506	3367
Arthritis	15	45	3.216623195566997	0.0012970883152152	Q14739,P06280,O75844,Q13510,Q14108,P51798,Q8WVQ1,P10321,P14174,O00170,Q96HY6,P04062,P51617,Q9NZ08,P21964	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,255,68,101,6,71,103,229,237,268,281,56,307,156,285	268,3181,2759,68,2169,598,1522,56,255,1265,229,2652,237,285,2702,306,1938,1530,307,71,2406,2708,1330,2711,2237,1707,1050,1224,101,6,289,821,1717,1236,103,733,2552,281,700,2157,564,156,1075,3053,1983	1.164537106940616,-1.2894537744189682,-0.7148241860051961,2.6926945390869426,-0.31242291199836886,0.6171918880980484,0.006307474011367515,2.888427682882454,1.2095131214680288,0.1451866537146581,1.3202624041063196,-0.6193116841420223,1.2762487791777117,1.1191654406700127,-0.6509657620201212,1.0503522207387042,-0.19434031752410985,0.006307474011367515,1.0503522207387042,2.6256544201008225,-0.4331220969912666,-0.6509657620201212,0.11769676093724667,-0.6509657620201212,-0.34234834725948426,-0.07877373131780484,0.2805565672472788,0.17253621044918402,2.2395519580884713,4.383005400114565,1.1191654406700127,0.4385882859122563,-0.07877373131780484,0.17253621044918402,2.2029028392455228,0.5158731784643796,-0.525427454868466,1.1419011221151822,0.5413858311413456,-0.2826609847711293,0.6671297810793578,1.7406977485275759,0.2805565672472788,-1.011660171259644,-0.19434031752410985	3367
Organophosphate ester transport	11	25	3.1834837541751897	0.0014551427870879	Q9Y255,Q14108,P41440,Q9BZF1,Q8WTV0,Q9HC21,P08183,Q9BSK2,P12236,Q9H2D1,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	100,6,167,400,9,107,146,314,361,86,125	645,995,146,1040,361,2002,2579,167,1528,2008,934,1224,6,660,125,9,875,470,314,400,880,86,107,1979,100	0.5667757956444454,0.30722341578558393,1.7808852976154201,0.2805565672472788,0.9571562106244959,-0.2236212584096826,-0.5565443734227432,1.6181799067894833,0.006307474011367515,-0.2236212584096826,0.3601597156898264,0.17253621044918402,4.383005400114565,0.5667757956444454,1.9578570786990497,4.324586732934785,0.41257400595833643,0.7899351985641869,1.0503522207387042,0.9099236880488443,0.41257400595833643,2.3657246319376566,2.165980585241542,-0.19434031752410985,2.2759315653971224	3367
Abnormal biliary tract morphology	14	25	3.1670122366626927	0.001540138375601	Q14739,Q92889,Q10713,Q14108,Q5XKP0,Q9UJW0,Q9Y276,P14174,P07602,P09601,Q9NZJ7,P04062,O43933,P48506	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,520,655,6,581,104,342,237,113,21,641,56,92,287	1454,92,1522,56,113,21,237,1634,2925,1094,287,1586,655,690,6,289,581,520,2313,2316,1563,641,104,342,1988	0.03437193328851483,2.294021415669942,0.006307474011367515,2.888427682882454,2.110076974296961,3.613683844728898,1.2762487791777117,-0.050263952997597124,-0.8777714879158465,0.25375565145434276,1.1191654406700127,-0.02190402285820215,0.5667757956444454,0.5413858311413456,4.383005400114565,1.1191654406700127,0.6422200972561323,0.7165975954483155,-0.3724389183184647,-0.3724389183184647,0.006307474011367515,0.5920441322650274,2.2029028392455228,1.0039634351651625,-0.19434031752410985	3367
Molecular transducer activity	10	30	3.162167177751172	0.001565996326724	Q5KU26,O15118,Q14108,Q8WTV0,Q15629,Q9BUN8,Q99720,O15173,P20645,P30536	Functions	GO Molecular function	msigdb_gomf	193,96,6,9,11,301,20,118,251,124	2530,1685,96,118,2220,1877,816,251,124,632,2229,1938,726,3046,1378,6,11,1433,1954,193,1280,9,698,383,20,301,2321,2521,743,1623	-0.525427454868466,-0.07877373131780484,2.2759315653971224,2.0535377021037875,-0.34234834725948426,-0.16521660034488708,0.4385882859122563,1.231854696356683,1.9771403969263128,0.5920441322650274,-0.34234834725948426,-0.19434031752410985,0.5158731784643796,-1.011660171259644,0.09006522764362623,4.383005400114565,4.156903668614397,0.062290731757696595,-0.19434031752410985,1.471397176367932,0.1451866537146581,4.324586732934785,0.5413858311413456,0.9335935466195544,3.641045663369028,1.07339179882247,-0.3724389183184647,-0.49448594888254555,0.5158731784643796,-0.02190402285820215	3367
Inorganic anion transport	9	20	3.1588534037660274	0.0015839114119287	Q9Y277,P21796,P51798,Q9UHG3,Q9C0H2,P08183,Q9UBX3,P30536,P45880	Processes and pathways	GO Biological process	msigdb_gobp	166,34,71,48,80,146,91,124,29	2756,1454,146,3263,34,124,29,71,2067,2236,1186,1223,263,3206,80,1791,91,48,166,3137	-0.7148241860051961,0.03437193328851483,1.7808852976154201,-1.5816442855181783,3.2722740469256966,1.9771403969263128,3.403217513344748,2.6256544201008225,-0.2530609609086133,-0.34234834725948426,0.19974671831673846,0.17253621044918402,1.187074181061587,-1.3611000187999303,2.4539090139419626,-0.1074347923116181,2.312045215706412,3.107165693020846,1.6388066898289295,-1.1836636419604167	3367
Azurophil granule membrane	9	22	3.1315508802695904	0.0017388565284144	P13473,P42785,P07602,O00462,Q92542,Q07065,O95721,O15260,P27105	Localization	GO Cellular component	msigdb_gocc	161,18,113,180,218,120,122,60,157	180,60,2489,2052,122,113,269,1039,161,157,2228,18,1182,120,769,1342,218,2554,3117,622,641,1979	1.5137692083085525,2.775214074894696,-0.49448594888254555,-0.2530609609086133,1.9963496087227715,2.110076974296961,1.164537106940616,0.2805565672472788,1.679809873082842,1.7204832487252557,-0.34234834725948426,3.8282095648532786,0.19974671831673846,2.0154852262905982,0.490236763907363,0.11769676093724667,1.3855822269020739,-0.525427454868466,-1.1488380282478365,0.6171918880980484,0.5920441322650274,-0.19434031752410985	3367
Glycoprotein metabolic process	25	57	3.12338416115944	0.0017878422584716	Q96L58,Q6ZXV5,Q10471,Q9BT22,O00754,O00462,Q10472,P46977,O60502,P04843,Q9NY61,Q9H4A6,Q92542,P04844,O43505,Q9H0U3,Q2TAA5,Q16706,Q86YN1,O15118,Q8WVQ1,Q7LGA3,Q08379,O60476,P14314	Processes and pathways	GO Biological process	msigdb_gobp	410,149,654,292,543,180,308,686,62,572,741,471,218,719,87,622,222,610,484,96,103,239,497,249,629	180,1800,543,2048,96,709,87,249,62,2286,1259,1572,2825,2615,2335,572,719,629,1818,1046,2228,686,3130,2665,1826,1148,2012,497,654,308,2183,2074,2593,610,222,149,239,1285,1286,484,908,103,218,1726,410,3314,1069,1023,292,622,2157,471,741,1739,1680,1412,1989	1.5137692083085525,-0.1362485904097433,0.6671297810793578,-0.2530609609086133,2.2759315653971224,0.5158731784643796,2.3478963961729225,1.231854696356683,2.7588221406548605,-0.3724389183184647,0.1451866537146581,-0.02190402285820215,-0.7794292005641262,-0.5878385067985065,-0.40269627647094874,0.6422200972561323,0.5158731784643796,0.5920441322650274,-0.1362485904097433,0.2805565672472788,-0.34234834725948426,0.5413858311413456,-1.1836636419604167,-0.6193116841420223,-0.1362485904097433,0.22681944749468783,-0.2236212584096826,0.7411577066416265,0.5667757956444454,1.0503522207387042,-0.31242291199836886,-0.2530609609086133,-0.5565443734227432,0.6171918880980484,1.3639014130956277,1.7608315718187155,1.2762487791777117,0.1451866537146581,0.1451866537146581,0.7656032541864601,0.38643153062342506,2.2029028392455228,1.3855822269020739,-0.07877373131780484,0.8861457519054411,-1.929324312075685,0.2805565672472788,0.30722341578558393,1.1191654406700127,0.6171918880980484,-0.2826609847711293,0.7899351985641869,0.5158731784643796,-0.07877373131780484,-0.050263952997597124,0.09006522764362623,-0.19434031752410985	3367
transporter	20	57	3.121523739987722	0.0017991774111096	O43615,Q8TEX9,Q9NR77,O00410,Q99595,P41440,O43772,Q9UJZ1,O60830,O15397,P53985,Q9C0E2,Q567V2,Q99808,Q8N1F7,Q92973,P52292,Q9H2D1,Q9HD45,Q15070	Functions	Panther Protein class	panther_protein_class	376,538,148,527,37,167,169,317,47,544,553,592,64,470,334,469,466,86,114,366	527,2327,1515,1415,1805,544,376,1454,169,2394,47,2223,1137,1143,2975,167,1528,761,466,2657,1703,1590,553,2067,653,3081,1146,2237,934,2135,2016,366,64,3206,584,334,2027,1850,538,803,469,2935,1068,1300,37,1069,470,3271,592,86,1071,114,148,1565,2212,317,1988	0.6919219483408452,-0.40269627647094874,0.006307474011367515,0.062290731757696595,-0.1362485904097433,0.6671297810793578,0.9335935466195544,0.03437193328851483,1.5974688426783576,-0.4331220969912666,3.107165693020846,-0.34234834725948426,0.22681944749468783,0.22681944749468783,-0.9443136123937819,1.6181799067894833,0.006307474011367515,0.490236763907363,0.7899351985641869,-0.6193116841420223,-0.07877373131780484,-0.02190402285820215,0.6671297810793578,-0.2530609609086133,0.5667757956444454,-1.0798288811157457,0.22681944749468783,-0.34234834725948426,0.3601597156898264,-0.2826609847711293,-0.2236212584096826,0.9571562106244959,2.742374563169135,-1.3611000187999303,0.6422200972561323,1.0039634351651625,-0.2236212584096826,-0.1362485904097433,0.6919219483408452,0.46447550012638145,0.7899351985641869,-0.8777714879158465,0.2805565672472788,0.1451866537146581,3.2722740469256966,0.2805565672472788,0.7899351985641869,-1.5816442855181783,0.6422200972561323,2.3657246319376566,0.2805565672472788,2.110076974296961,1.7808852976154201,0.006307474011367515,-0.31242291199836886,1.0503522207387042,-0.19434031752410985	3367
Lytic vacuole organization	9	25	3.120844007877419	0.0018033353238087	P11117,P50897,Q14108,Q86VS8,O14773,P54802,P04062,O75503,Q8N511	Processes and pathways	GO Biological process	msigdb_gobp	69,38,6,264,108,109,56,57,90	473,108,57,814,56,2649,269,69,601,38,2235,109,2130,656,6,769,264,90,828,1344,1910,2272,2916,567,1980	0.7656032541864601,2.1474158808446684,2.8563508480242543,0.4385882859122563,2.888427682882454,-0.6193116841420223,1.164537106940616,2.64250124049558,0.6171918880980484,3.2574988008466623,-0.34234834725948426,2.1474158808446684,-0.2826609847711293,0.5667757956444454,4.383005400114565,0.490236763907363,1.187074181061587,2.33000339930892,0.4385882859122563,0.11769676093724667,-0.16521660034488708,-0.34234834725948426,-0.8447967022235733,0.6671297810793578,-0.19434031752410985	3367
Receptor	7	28	3.110986411471494	0.0018646351959232	Q567V2,Q14108,Q8WTV0,Q9UQB8,A6NIH7,Q9NR77,P20645	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	64,6,9,14,179,148,251	179,1415,963,1318,713,1809,2055,1877,816,251,2229,607,6,1103,1151,64,905,1280,1011,9,1852,301,1071,1793,148,2428,2689,14	1.5137692083085525,0.062290731757696595,0.3337574021162552,0.11769676093724667,0.5158731784643796,-0.1362485904097433,-0.2530609609086133,-0.16521660034488708,0.4385882859122563,1.231854696356683,-0.34234834725948426,0.6171918880980484,4.383005400114565,0.25375565145434276,0.22681944749468783,2.742374563169135,0.38643153062342506,0.1451866537146581,0.30722341578558393,4.324586732934785,-0.1362485904097433,1.07339179882247,0.2805565672472788,-0.1074347923116181,1.7808852976154201,-0.4331220969912666,-0.6193116841420223,4.083110142233152	3367
Organic acid transmembrane transport	12	26	3.1099736043404502	0.0018710406329851	Q15041,P41440,O43772,O75746,P31751,P23786,O95563,P08183,P30825,Q9H2D1,P53985,Q9UBX3	Processes and pathways	GO Biological process	msigdb_gobp	295,167,169,508,574,207,545,146,85,86,553,91	169,1517,508,1873,545,1877,146,1091,1215,207,855,85,574,2175,167,1181,1590,553,1223,295,1433,86,1972,1561,91,677	1.5974688426783576,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,-0.16521660034488708,1.7808852976154201,0.25375565145434276,0.17253621044918402,1.4286699849010147,0.41257400595833643,2.3834885282361222,0.6422200972561323,-0.31242291199836886,1.6181799067894833,0.19974671831673846,-0.02190402285820215,0.6671297810793578,0.17253621044918402,1.0963292676298746,0.062290731757696595,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.312045215706412,0.5667757956444454	3367
Predicted secreted proteins	19	48	3.107327435785191	0.0018878716795656	P80303,P43490,Q9UM22,Q15165,Q08380,Q9BUR5,P30740,Q9NZ08,O00584,P05067,P26583,P09429,Q9UMX5,Q8WUJ1,Q02818,Q9HB40,Q9Y4P3,Q9P2K2,P14174	Functions	Protein Atlas Protein class	protein_atlas_protein_class	1,257,13,15,143,412,530,156,153,160,294,417,45,312,54,58,344,488,237	153,2530,2286,895,1628,1874,529,753,160,1090,1697,417,2733,237,1930,2340,3076,294,530,257,2006,2406,1373,2008,1,3346,54,1101,143,2071,1895,1378,15,3343,312,3105,1198,1730,412,1556,2377,1306,58,156,488,13,45,344	1.7406977485275759,-0.525427454868466,-0.3724389183184647,0.38643153062342506,-0.050263952997597124,-0.16521660034488708,0.6919219483408452,0.490236763907363,1.7001874873242686,0.25375565145434276,-0.07877373131780484,0.862258844628111,-0.682802624960496,1.2762487791777117,-0.19434031752410985,-0.40269627647094874,-1.0798288811157457,1.0963292676298746,0.6919219483408452,1.2095131214680288,-0.2236212584096826,-0.4331220969912666,0.09006522764362623,-0.2236212584096826,4.739957488800412,-2.559722816212025,2.9519476787527323,0.25375565145434276,1.820754742930303,-0.2530609609086133,-0.16521660034488708,0.09006522764362623,3.9828351848149777,-2.471633129018289,1.0503522207387042,-1.1142272342228774,0.19974671831673846,-0.07877373131780484,0.8861457519054411,0.006307474011367515,-0.40269627647094874,0.1451866537146581,2.840232108692598,1.7406977485275759,0.7656032541864601,4.144687074033624,3.137614127937716,1.0039634351651625	3367
Organic anion transport	18	39	3.1064095960721247	0.0018937420382363	Q6NUK1,Q15041,P41440,P80404,Q9HC21,O75746,Q9UJS0,P14174,O95563,Q99808,P07602,P30825,Q9H2D1,P12236,Q9NZJ7,P53985,Q9UBX3,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	660,295,167,234,107,508,677,237,545,470,113,85,86,361,641,553,91,125	961,645,1517,508,1873,545,753,995,1877,113,1091,1215,1040,361,237,855,85,167,1590,553,2236,234,1223,1226,295,2188,1433,660,2192,125,470,86,1972,1561,107,641,91,2483,677	0.3337574021162552,0.5667757956444454,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.490236763907363,0.30722341578558393,-0.16521660034488708,2.110076974296961,0.25375565145434276,0.17253621044918402,0.2805565672472788,0.9571562106244959,1.2762487791777117,0.41257400595833643,2.3834885282361222,1.6181799067894833,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,1.2983027806935246,0.17253621044918402,0.17253621044918402,1.0963292676298746,-0.31242291199836886,0.062290731757696595,0.5667757956444454,-0.31242291199836886,1.9578570786990497,0.7899351985641869,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,0.5920441322650274,2.312045215706412,-0.4637180795900233,0.5667757956444454	3367
Endoplasmic reticulum golgi intermediate compartment membrane	14	22	3.0972446299788303	0.0019532860993614	P24390,O95070,P49257,P49755,P51572,Q13190,Q9Y3B3,Q9Y282,Q15904,Q08379,Q10472,Q9BVK6,Q8N511,O15260	Localization	GO Cellular component	msigdb_gocc	2,377,496,511,238,365,219,84,182,497,308,640,90,60	60,1037,963,1807,377,2,2538,496,511,238,2501,497,308,975,365,182,90,875,640,669,84,219	2.775214074894696,0.2805565672472788,0.3337574021162552,-0.1362485904097433,0.9335935466195544,4.631429349052777,-0.525427454868466,0.7411577066416265,0.7165975954483155,1.2762487791777117,-0.49448594888254555,0.7411577066416265,1.0503522207387042,0.3337574021162552,0.9571562106244959,1.5137692083085525,2.33000339930892,0.41257400595833643,0.5920441322650274,0.5667757956444454,2.401188502744234,1.3855822269020739	3367
Biliary tract abnormality	11	29	3.08414095484868	0.0020414085101037	Q14739,Q14108,Q9UJW0,Q9Y276,O96028,P14174,P07602,P09601,P04062,O43933,P48506	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,6,104,342,236,237,113,21,56,92,287	1454,92,330,236,1522,56,113,21,237,1634,2925,1094,287,1586,655,690,2953,6,289,581,520,2313,2316,2425,1563,641,104,342,1988	0.03437193328851483,2.294021415669942,1.0039634351651625,1.2762487791777117,0.006307474011367515,2.888427682882454,2.110076974296961,3.613683844728898,1.2762487791777117,-0.050263952997597124,-0.8777714879158465,0.25375565145434276,1.1191654406700127,-0.02190402285820215,0.5667757956444454,0.5413858311413456,-0.9109430815275097,4.383005400114565,1.1191654406700127,0.6422200972561323,0.7165975954483155,-0.3724389183184647,-0.3724389183184647,-0.4331220969912666,0.006307474011367515,0.5920441322650274,2.2029028392455228,1.0039634351651625,-0.19434031752410985	3367
Organic anion transmembrane transporter activity	13	25	3.067207742120046	0.0021606863532805	Q6NUK1,P41440,Q9HC21,O75746,Q9UJS0,O95563,Q99808,P30825,Q9H2D1,P12236,P53985,Q9UBX3,Q8TB61	Functions	GO Molecular function	msigdb_gomf	660,167,107,508,677,545,470,85,86,361,553,91,125	961,645,508,545,995,1091,1215,1040,361,85,167,1590,553,1223,1433,660,2192,125,470,86,1972,1561,107,91,677	0.3337574021162552,0.5667757956444454,0.7165975954483155,0.6671297810793578,0.30722341578558393,0.25375565145434276,0.17253621044918402,0.2805565672472788,0.9571562106244959,2.3834885282361222,1.6181799067894833,-0.02190402285820215,0.6671297810793578,0.17253621044918402,0.062290731757696595,0.5667757956444454,-0.31242291199836886,1.9578570786990497,0.7899351985641869,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,2.312045215706412,0.5667757956444454	3367
Intrinsic component of mitochondrial inner membrane	18	28	3.05856137083241	0.0022240252016421	Q13505,Q6UXV4,Q99595,Q9H3K2,O14925,Q5XKP0,O75880,Q9HC21,O60830,O95563,Q9NX63,Q9UG56,Q9Y512,Q9BUR5,Q15070,Q9Y2R0,Q53H12,Q16891	Localization	GO Cellular component	msigdb_gocc	99,121,37,672,262,581,597,107,47,545,316,742,644,412,366,26,440,381	262,1455,47,2331,597,545,3143,1186,99,366,767,381,440,581,121,1604,37,412,672,1561,2480,107,1310,316,742,26,1133,644	1.187074181061587,0.03437193328851483,3.107165693020846,-0.40269627647094874,0.6171918880980484,0.6671297810793578,-1.2187064928309388,0.19974671831673846,2.2759315653971224,0.9571562106244959,0.490236763907363,0.9335935466195544,0.8382620619356581,0.6422200972561323,2.0154852262905982,-0.02190402285820215,3.2722740469256966,0.8861457519054411,0.5667757956444454,0.006307474011367515,-0.4637180795900233,2.165980585241542,0.1451866537146581,1.0503522207387042,0.5158731784643796,3.5306255572552185,0.25375565145434276,0.5920441322650274	3367
Ceramide metabolic process	9	18	3.0580395681622385	0.0022279015646742	P06280,P06865,Q13510,Q8NCC3,Q96G23,P04062,Q53H12,O95470,P17900	Processes and pathways	GO Biological process	msigdb_gobp	255,347,101,10,43,56,440,123,221	448,1317,123,56,255,347,2649,221,756,1218,1224,1226,101,440,10,43,1069,1204	0.8141544886580385,0.11769676093724667,1.9771403969263128,2.888427682882454,1.2095131214680288,0.9806125526787869,-0.6193116841420223,1.3639014130956277,0.490236763907363,0.17253621044918402,0.17253621044918402,0.17253621044918402,2.2395519580884713,0.8382620619356581,4.301006972369739,3.1829254312869844,0.2805565672472788,0.19974671831673846	3367
Glycoprotein biosynthetic process	22	50	3.0456793808331035	0.0023215524919049	Q96L58,Q6ZXV5,Q10471,Q9BT22,Q10472,P46977,O60502,P04843,Q9NY61,Q9H4A6,Q92542,P04844,O43505,Q9H0U3,Q2TAA5,Q16706,Q86YN1,O15118,Q8WVQ1,Q7LGA3,Q08379,O60476	Processes and pathways	GO Biological process	msigdb_gobp	410,149,654,292,308,686,62,572,741,471,218,719,87,622,222,610,484,96,103,239,497,249	1800,2048,96,709,87,249,62,2286,1259,1572,2825,2615,2335,572,719,1818,1046,2228,686,3130,1826,1148,2012,497,654,308,2183,2074,610,222,149,239,1285,1286,484,908,103,218,1726,410,1069,292,622,2157,471,741,1739,1680,1412,1989	-0.1362485904097433,-0.2530609609086133,2.2759315653971224,0.5158731784643796,2.3478963961729225,1.231854696356683,2.7588221406548605,-0.3724389183184647,0.1451866537146581,-0.02190402285820215,-0.7794292005641262,-0.5878385067985065,-0.40269627647094874,0.6422200972561323,0.5158731784643796,-0.1362485904097433,0.2805565672472788,-0.34234834725948426,0.5413858311413456,-1.1836636419604167,-0.1362485904097433,0.22681944749468783,-0.2236212584096826,0.7411577066416265,0.5667757956444454,1.0503522207387042,-0.31242291199836886,-0.2530609609086133,0.6171918880980484,1.3639014130956277,1.7608315718187155,1.2762487791777117,0.1451866537146581,0.1451866537146581,0.7656032541864601,0.38643153062342506,2.2029028392455228,1.3855822269020739,-0.07877373131780484,0.8861457519054411,0.2805565672472788,1.1191654406700127,0.6171918880980484,-0.2826609847711293,0.7899351985641869,0.5158731784643796,-0.07877373131780484,-0.050263952997597124,0.09006522764362623,-0.19434031752410985	3367
Ion transport	18	43	3.0255071838496894	0.0024821650803767	Q9Y277,P21796,Q15043,P51798,Q93050,Q658P3,Q9UI12,Q6P4Q7,Q9C0H2,O75964,Q8NE01,P56385,Q15904,O95202,Q9Y487,P06576,P16615,P45880	Processes and pathways	Protein Atlas Biological process	protein_atlas_biological_process	166,34,263,71,265,189,341,369,80,17,335,214,182,330,358,250,305,29	2756,851,17,330,1361,1213,250,3263,305,927,548,2897,34,378,1580,759,970,2498,29,2928,71,792,2236,2296,214,2502,1839,263,182,189,3206,369,335,1604,265,948,591,80,1791,341,166,358,3137	-0.7148241860051961,0.41257400595833643,3.867353512797234,1.0039634351651625,0.09006522764362623,0.17253621044918402,1.231854696356683,-1.5816442855181783,1.0503522207387042,0.3601597156898264,0.6671297810793578,-0.8447967022235733,3.2722740469256966,0.9335935466195544,-0.02190402285820215,0.490236763907363,0.3337574021162552,-0.49448594888254555,3.403217513344748,-0.8777714879158465,2.6256544201008225,0.46447550012638145,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.1362485904097433,1.187074181061587,1.5137692083085525,1.4926272539284748,-1.3611000187999303,0.9571562106244959,1.0039634351651625,-0.02190402285820215,1.187074181061587,0.3601597156898264,0.6422200972561323,2.4539090139419626,-0.1074347923116181,1.0039634351651625,1.6388066898289295,0.9806125526787869,-1.1836636419604167	3367
Steroid metabolic process	17	71	3.010482479776841	0.0026083299539803	P05067,Q14739,Q9BQE5,Q16850,O15118,Q13510,P49748,Q8WTV0,Q15392,Q15800,Q15125,P34913,P04062,Q9UBM7,O95470,P30536,Q14849	Processes and pathways	GO Biological process	msigdb_gobp	160,289,3,131,96,101,233,9,79,110,177,181,56,185,123,124,31	2048,2328,96,1808,123,3182,56,1213,160,3317,1632,1633,2763,293,2002,2579,3348,3057,855,124,181,1046,2125,1366,3228,2769,930,233,1328,1586,1763,2349,2660,2008,1534,3231,1050,974,1226,101,3019,938,289,31,2459,177,2985,79,1008,1277,2842,110,131,351,769,1237,9,1609,1241,877,3152,3,2478,880,1401,1245,185,1131,1409,2483,2967	-0.2530609609086133,-0.40269627647094874,2.2759315653971224,-0.1362485904097433,1.9771403969263128,-1.2894537744189682,2.888427682882454,0.17253621044918402,1.7001874873242686,-1.9692873222146825,-0.050263952997597124,-0.050263952997597124,-0.7148241860051961,1.0963292676298746,-0.2236212584096826,-0.5565443734227432,-2.604267148830522,-1.0456406280505959,0.41257400595833643,1.9771403969263128,1.5137692083085525,0.2805565672472788,-0.2826609847711293,0.09006522764362623,-1.4336660463047972,-0.7148241860051961,0.3601597156898264,1.2983027806935246,0.11769676093724667,-0.02190402285820215,-0.1074347923116181,-0.40269627647094874,-0.6193116841420223,-0.2236212584096826,0.006307474011367515,-1.4336660463047972,0.2805565672472788,0.3337574021162552,0.17253621044918402,2.2395519580884713,-0.977885243317303,0.3601597156898264,1.1191654406700127,3.3454673481684774,-0.4637180795900233,1.5348236972160396,-0.9443136123937819,2.471357400586925,0.30722341578558393,0.1451866537146581,-0.7794292005641262,2.1287815015903986,1.9190660482263868,0.9806125526787869,0.490236763907363,0.17253621044918402,4.324586732934785,-0.02190402285820215,0.17253621044918402,0.41257400595833643,-1.2187064928309388,4.54267192090626,-0.4637180795900233,0.41257400595833643,0.09006522764362623,0.17253621044918402,1.5137692083085525,0.25375565145434276,0.09006522764362623,-0.4637180795900233,-0.9109430815275097	3367
Membrane lipid biosynthetic process	8	22	2.983684272036646	0.0028480048469958	Q9H490,Q13510,Q96G23,Q06136,Q8NBX0,P04062,Q53H12,O95470	Processes and pathways	GO Biological process	msigdb_gobp	261,101,43,142,116,56,440,123	448,1317,1572,123,56,2002,756,1224,142,1226,101,440,116,2312,1969,43,667,1069,261,1204,704,1979	0.8141544886580385,0.11769676093724667,-0.02190402285820215,1.9771403969263128,2.888427682882454,-0.2236212584096826,0.490236763907363,0.17253621044918402,1.820754742930303,0.17253621044918402,2.2395519580884713,0.8382620619356581,2.072455559506005,-0.3724389183184647,-0.19434031752410985,3.1829254312869844,0.5667757956444454,0.2805565672472788,1.2095131214680288,0.19974671831673846,0.5413858311413456,-0.19434031752410985	3367
Glycosidase	9	19	2.977416776515776	0.0029068855228135	P06280,P16278,P04066,P54802,P10253,O00462,P04062,O60476,O60502	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	255,5,319,109,269,180,56,249,62	180,543,2488,249,62,56,319,255,347,2649,269,5,1935,109,2547,2183,2593,610,1730	1.5137692083085525,0.6671297810793578,-0.49448594888254555,1.231854696356683,2.7588221406548605,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.6193116841420223,1.164537106940616,4.4292036485047825,-0.19434031752410985,2.1474158808446684,-0.525427454868466,-0.31242291199836886,-0.5565443734227432,0.6171918880980484,-0.07877373131780484	3367
Vacuole organization	12	54	2.977090852411056	0.0029099776309124	Q9UNZ2,Q14108,P50897,Q86VS8,P11117,O14773,P54802,P10253,P53365,P04062,O75503,Q8N511	Processes and pathways	GO Biological process	msigdb_gobp	296,6,38,264,69,108,109,269,147,56,57,90	473,108,1807,57,814,2795,2056,56,1697,2649,269,69,305,1758,601,1530,38,2235,147,109,2544,2130,2665,656,6,2188,2247,610,769,264,459,90,872,909,828,875,2814,1344,1910,2638,1614,1125,2272,884,2916,567,1980,2042,3157,296,2215,2887,2889,1569	0.7656032541864601,2.1474158808446684,-0.1362485904097433,2.8563508480242543,0.4385882859122563,-0.7470323872777213,-0.2530609609086133,2.888427682882454,-0.07877373131780484,-0.6193116841420223,1.164537106940616,2.64250124049558,1.0503522207387042,-0.1074347923116181,0.6171918880980484,0.006307474011367515,3.2574988008466623,-0.34234834725948426,1.7808852976154201,2.1474158808446684,-0.525427454868466,-0.2826609847711293,-0.6193116841420223,0.5667757956444454,4.383005400114565,-0.31242291199836886,-0.34234834725948426,0.6171918880980484,0.490236763907363,1.187074181061587,0.8141544886580385,2.33000339930892,0.41257400595833643,0.38643153062342506,0.4385882859122563,0.41257400595833643,-0.7470323872777213,0.11769676093724667,-0.16521660034488708,-0.5878385067985065,-0.02190402285820215,0.25375565145434276,-0.34234834725948426,0.41257400595833643,-0.8447967022235733,0.6671297810793578,-0.19434031752410985,-0.2236212584096826,-1.2187064928309388,1.0963292676298746,-0.31242291199836886,-0.8120166279085533,-0.8120166279085533,0.006307474011367515	3367
membrane trafficking regulatory protein	10	21	2.9644148296658765	0.0030325917685032	P13473,P24390,Q14108,Q9P253,Q8WTV0,Q15075,O00471,Q96EA4,O00560,Q15833	Functions	Panther Protein class	panther_protein_class	161,2,6,567,9,367,681,619,625,380	1990,681,625,682,1753,1039,161,2,6,367,2411,380,9,1439,909,828,619,1858,1562,1979,567	-0.2236212584096826,0.5413858311413456,0.5920441322650274,0.5413858311413456,-0.1074347923116181,0.2805565672472788,1.679809873082842,4.631429349052777,4.383005400114565,0.9571562106244959,-0.4331220969912666,0.9335935466195544,4.324586732934785,0.062290731757696595,0.38643153062342506,0.4385882859122563,0.6171918880980484,-0.1362485904097433,0.006307474011367515,-0.19434031752410985,0.6671297810793578	3367
Lipid localization	23	76	2.9579142222771475	0.0030972829922282	Q9BQE5,P35790,Q14108,Q9BZF1,Q8WTV0,P08183,Q99720,Q9BUR5,Q14849,O43772,Q9UJZ1,O60664,P04062,O15260,O95674,Q9H6V9,P23786,P17900,Q9Y255,O15118,P14174,P07602,P30536	Processes and pathways	GO Biological process	msigdb_gobp	3,256,6,400,9,146,20,412,31,169,317,415,56,60,436,67,207,221,100,96,237,113,124	680,3360,2328,96,60,169,645,415,1806,964,1264,436,2120,2798,56,753,1697,113,2649,1575,146,1215,237,221,2002,2579,207,855,1581,124,574,2175,1046,256,1528,1181,2008,934,1534,1224,3114,3046,1226,6,938,31,3188,769,2192,459,3343,1292,9,1609,875,1241,20,3,3256,412,2479,400,1733,880,1245,67,2916,641,1979,504,1131,542,317,3157,100,2113	0.5413858311413456,-5.050618198378846,-0.40269627647094874,2.2759315653971224,2.775214074894696,1.5974688426783576,0.5667757956444454,0.862258844628111,-0.1362485904097433,0.3337574021162552,0.1451866537146581,0.8382620619356581,-0.2826609847711293,-0.7470323872777213,2.888427682882454,0.490236763907363,-0.07877373131780484,2.110076974296961,-0.6193116841420223,-0.02190402285820215,1.7808852976154201,0.17253621044918402,1.2762487791777117,1.3639014130956277,-0.2236212584096826,-0.5565443734227432,1.4286699849010147,0.41257400595833643,-0.02190402285820215,1.9771403969263128,0.6422200972561323,-0.31242291199836886,0.2805565672472788,1.2095131214680288,0.006307474011367515,0.19974671831673846,-0.2236212584096826,0.3601597156898264,0.006307474011367515,0.17253621044918402,-1.1488380282478365,-1.011660171259644,0.17253621044918402,4.383005400114565,0.3601597156898264,3.3454673481684774,-1.2894537744189682,0.490236763907363,-0.31242291199836886,0.8141544886580385,-2.471633129018289,0.1451866537146581,4.324586732934785,-0.02190402285820215,0.41257400595833643,0.17253621044918402,3.641045663369028,4.54267192090626,-1.507173381664675,0.8861457519054411,-0.4637180795900233,0.9099236880488443,-0.07877373131780484,0.41257400595833643,0.17253621044918402,2.709311108656073,-0.8447967022235733,0.5920441322650274,-0.19434031752410985,0.7411577066416265,0.25375565145434276,0.6919219483408452,1.0503522207387042,-1.2187064928309388,2.2759315653971224,-0.2530609609086133	3367
Glycoside hydrolase superfamily [IPR017853]	8	16	2.922594810031286	0.0034712792032989	P06280,P16278,P04066,P54802,P10253,O00462,P04062,O60502	Sequence	InterPro Superfamily	interpro_homologous_superfamily	255,5,319,109,269,180,56,62	180,62,56,319,255,347,2649,1091,269,5,1935,109,2356,2593,1730,1503	1.5137692083085525,2.7588221406548605,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.6193116841420223,0.25375565145434276,1.164537106940616,4.4292036485047825,-0.19434031752410985,2.1474158808446684,-0.40269627647094874,-0.5565443734227432,-0.07877373131780484,0.03437193328851483	3367
Mitochondrial carrier domain superfamily [IPR023395]	11	19	2.909919059469373	0.0036152236841571	Q6NUK1,O43772,Q9HC21,O75746,Q9UJS0,Q70HW3,Q9BSK2,P12236,Q9H2D1,Q9NZJ7,Q9UBX3	Sequence	InterPro Superfamily	interpro_homologous_superfamily	660,169,107,508,677,77,314,361,86,641,91	169,645,508,995,1040,361,1590,1186,1223,660,77,314,86,1972,107,641,91,677,919	1.5974688426783576,0.5667757956444454,0.7165975954483155,0.30722341578558393,0.2805565672472788,0.9571562106244959,-0.02190402285820215,0.19974671831673846,0.17253621044918402,0.5667757956444454,2.5060688955133497,1.0503522207387042,2.3657246319376566,-0.19434031752410985,2.165980585241542,0.5920441322650274,2.312045215706412,0.5667757956444454,0.38643153062342506	3367
Mitochondrial substrate/solute carrier [IPR018108]	11	19	2.909919059469373	0.0036152236841571	Q6NUK1,O43772,Q9HC21,O75746,Q9UJS0,Q70HW3,Q9BSK2,P12236,Q9H2D1,Q9NZJ7,Q9UBX3	Sequence	InterPro Repeat	interpro_repeat	660,169,107,508,677,77,314,361,86,641,91	169,645,508,995,1040,361,1590,1186,1223,660,77,314,86,1972,107,641,91,677,919	1.5974688426783576,0.5667757956444454,0.7165975954483155,0.30722341578558393,0.2805565672472788,0.9571562106244959,-0.02190402285820215,0.19974671831673846,0.17253621044918402,0.5667757956444454,2.5060688955133497,1.0503522207387042,2.3657246319376566,-0.19434031752410985,2.165980585241542,0.5920441322650274,2.312045215706412,0.5667757956444454,0.38643153062342506	3367
SLC25 family of mitochondrial transporters	11	19	2.909919059469373	0.0036152236841571	Q6NUK1,O43772,Q9HC21,O75746,Q9UJS0,Q70HW3,Q9BSK2,P12236,Q9H2D1,Q9NZJ7,Q9UBX3	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	660,169,107,508,677,77,314,361,86,641,91	169,645,508,995,1040,361,1590,1186,1223,660,77,314,86,1972,107,641,91,677,919	1.5974688426783576,0.5667757956444454,0.7165975954483155,0.30722341578558393,0.2805565672472788,0.9571562106244959,-0.02190402285820215,0.19974671831673846,0.17253621044918402,0.5667757956444454,2.5060688955133497,1.0503522207387042,2.3657246319376566,-0.19434031752410985,2.165980585241542,0.5920441322650274,2.312045215706412,0.5667757956444454,0.38643153062342506	3367
Protein insertion into membrane	8	23	2.90333560619787	0.0036921075134825	Q9NS69,Q96A33,Q15629,Q9Y276,O14737,Q15070,Q9P0J0,P46379	Processes and pathways	GO Biological process	msigdb_gobp	0,431,11,342,205,366,386,30	205,1454,1992,2761,648,2290,1934,30,2237,1480,366,11,440,2307,1658,1547,1196,431,0,386,342,644,2755	1.4286699849010147,0.03437193328851483,-0.2236212584096826,-0.7148241860051961,0.5667757956444454,-0.3724389183184647,-0.19434031752410985,3.3454673481684774,-0.34234834725948426,0.03437193328851483,0.9571562106244959,4.156903668614397,0.8382620619356581,-0.3724389183184647,-0.050263952997597124,0.006307474011367515,0.19974671831673846,0.862258844628111,4.803828948758111,0.9335935466195544,1.0039634351651625,0.5920441322650274,-0.682802624960496	3367
Sterol metabolic process	14	40	2.9022121005306643	0.0037053757129128	P05067,Q14739,Q9BQE5,Q16850,O15118,P49748,Q8WTV0,Q15392,Q15800,Q15125,P34913,P04062,Q9UBM7,Q14849	Processes and pathways	GO Biological process	msigdb_gobp	160,289,3,131,96,233,9,79,110,177,181,56,185,31	96,1808,3182,56,160,1632,1633,293,3348,181,1046,2125,3228,2769,930,233,1763,2349,2660,2008,1534,3231,1050,1226,3019,938,289,31,2459,177,2985,79,2842,110,131,9,3,185,1131,2483	2.2759315653971224,-0.1362485904097433,-1.2894537744189682,2.888427682882454,1.7001874873242686,-0.050263952997597124,-0.050263952997597124,1.0963292676298746,-2.604267148830522,1.5137692083085525,0.2805565672472788,-0.2826609847711293,-1.4336660463047972,-0.7148241860051961,0.3601597156898264,1.2983027806935246,-0.1074347923116181,-0.40269627647094874,-0.6193116841420223,-0.2236212584096826,0.006307474011367515,-1.4336660463047972,0.2805565672472788,0.17253621044918402,-0.977885243317303,0.3601597156898264,1.1191654406700127,3.3454673481684774,-0.4637180795900233,1.5348236972160396,-0.9443136123937819,2.471357400586925,-0.7794292005641262,2.1287815015903986,1.9190660482263868,4.324586732934785,4.54267192090626,1.5137692083085525,0.25375565145434276,-0.4637180795900233	3367
Hydrolase activity hydrolyzing o glycosyl compounds	10	23	2.8934870120423075	0.0038099004723111	P06280,P16278,P04066,P54802,P10253,O00462,P04062,O60476,P17900,O60502	Functions	GO Molecular function	msigdb_gomf	255,5,319,109,269,180,56,249,221,62	180,543,249,62,56,319,255,347,2649,269,5,221,1935,109,2356,2183,2593,610,2084,1730,1028,2964,3002	1.5137692083085525,0.6671297810793578,1.231854696356683,2.7588221406548605,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.6193116841420223,1.164537106940616,4.4292036485047825,1.3639014130956277,-0.19434031752410985,2.1474158808446684,-0.40269627647094874,-0.31242291199836886,-0.5565443734227432,0.6171918880980484,-0.2530609609086133,-0.07877373131780484,0.30722341578558393,-0.9109430815275097,-0.9443136123937819	3367
Protein localization	31	69	2.8852127135913777	0.0039114927689711	Q9NS69,P51648,O43615,O14925,O75746,Q9UJS0,Q2T9J0,Q9NR77,P09601,P56589,Q15067,P46379,P05067,Q5JRX3,Q10713,Q99595,P21796,P50402,O60830,Q9NX63,P34913,O00116,Q9Y276,O43933,Q13505,O15254,O15228,Q13190,Q9Y512,P12236,P06576	Processes and pathways	Reactome Pathways	msigdb_reactome	0,128,376,262,508,677,395,148,21,533,279,30,160,658,655,37,34,420,47,316,181,571,342,92,99,346,474,365,644,361,250	571,2048,262,2328,474,346,376,1454,1992,645,92,47,713,3201,2331,2647,3095,508,2760,2761,2168,1361,160,250,1756,3317,21,1999,1040,361,1930,34,2579,1580,855,181,3226,3143,30,420,128,1586,533,3356,3128,655,2627,365,99,279,395,2018,658,1658,1848,2313,37,2992,1307,148,0,316,1979,2821,677,342,1132,644,2755	0.6422200972561323,-0.2530609609086133,1.187074181061587,-0.40269627647094874,0.7656032541864601,0.9806125526787869,0.9335935466195544,0.03437193328851483,-0.2236212584096826,0.5667757956444454,2.294021415669942,3.107165693020846,0.5158731784643796,-1.3611000187999303,-0.40269627647094874,-0.6193116841420223,-1.1142272342228774,0.7165975954483155,-0.7148241860051961,-0.7148241860051961,-0.31242291199836886,0.09006522764362623,1.7001874873242686,1.231854696356683,-0.1074347923116181,-1.9692873222146825,3.613683844728898,-0.2236212584096826,0.2805565672472788,0.9571562106244959,-0.19434031752410985,3.2722740469256966,-0.5565443734227432,-0.02190402285820215,0.41257400595833643,1.5137692083085525,-1.4336660463047972,-1.2187064928309388,3.3454673481684774,0.862258844628111,1.9384991366690936,-0.02190402285820215,0.6919219483408452,-3.3665191515672723,-1.1836636419604167,0.5667757956444454,-0.5878385067985065,0.9571562106244959,2.2759315653971224,1.1419011221151822,0.9099236880488443,-0.2236212584096826,0.5667757956444454,-0.050263952997597124,-0.1362485904097433,-0.3724389183184647,3.2722740469256966,-0.9443136123937819,0.1451866537146581,1.7808852976154201,4.803828948758111,1.0503522207387042,-0.19434031752410985,-0.7470323872777213,0.5667757956444454,1.0039634351651625,0.25375565145434276,0.5920441322650274,-0.682802624960496	3367
Serine hydrolase activity	6	19	2.8650394443560425	0.0041695730160689	P67812,P10619,Q9H3G5,P42785,Q16740,Q9HB40	Functions	GO Molecular function	msigdb_gomf	98,40,12,18,89,58	108,403,40,2947,2899,1094,18,2542,1703,2501,98,89,395,439,658,905,2877,12,58	2.1474158808446684,0.8861457519054411,3.227809668601115,-0.9109430815275097,-0.8447967022235733,0.25375565145434276,3.8282095648532786,-0.525427454868466,-0.07877373131780484,-0.49448594888254555,2.2759315653971224,2.33000339930892,0.9099236880488443,0.8382620619356581,0.5667757956444454,0.38643153062342506,-0.8120166279085533,4.144687074033624,2.840232108692598	3367
Anion transmembrane transporter activity	19	37	2.845756349674776	0.0044306081374885	Q15043,O75746,Q9UJS0,P45880,Q6NUK1,P21796,Q9Y277,P41440,O95563,P53985,P51798,Q9C0H2,Q99808,P30825,Q9H2D1,Q9UBX3,Q9HC21,P12236,Q8TB61	Functions	GO Molecular function	msigdb_gomf	263,508,677,29,660,34,166,167,545,553,71,80,470,85,86,91,107,361,125	2756,961,1454,645,508,545,995,1091,3263,1215,1040,361,34,85,167,29,71,1590,553,2236,1223,263,1433,3206,660,2192,125,470,80,86,1972,1561,107,91,677,166,3137	-0.7148241860051961,0.3337574021162552,0.03437193328851483,0.5667757956444454,0.7165975954483155,0.6671297810793578,0.30722341578558393,0.25375565145434276,-1.5816442855181783,0.17253621044918402,0.2805565672472788,0.9571562106244959,3.2722740469256966,2.3834885282361222,1.6181799067894833,3.403217513344748,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,0.17253621044918402,1.187074181061587,0.062290731757696595,-1.3611000187999303,0.5667757956444454,-0.31242291199836886,1.9578570786990497,0.7899351985641869,2.4539090139419626,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,2.312045215706412,0.5667757956444454,1.6388066898289295,-1.1836636419604167	3367
Lipid transporter activity	6	20	2.837578721649665	0.0045457135782691	Q9Y255,O15118,P08183,P30536,P17900,Q14849	Functions	GO Molecular function	msigdb_gomf	100,96,146,124,221,31	2328,96,146,1215,221,2002,855,124,1528,2008,934,31,2192,875,1241,2479,400,880,1245,100	-0.40269627647094874,2.2759315653971224,1.7808852976154201,0.17253621044918402,1.3639014130956277,-0.2236212584096826,0.41257400595833643,1.9771403969263128,0.006307474011367515,-0.2236212584096826,0.3601597156898264,3.3454673481684774,-0.31242291199836886,0.41257400595833643,0.17253621044918402,-0.4637180795900233,0.9099236880488443,0.41257400595833643,0.17253621044918402,2.2759315653971224	3367
Cellular ion homeostasis	27	79	2.819849017909186	0.0048046249889424	Q96PU5,Q15043,Q93050,P09601,Q8IYU8,P05067,Q96A33,P50897,Q9HD20,P09429,Q9UJZ1,Q96TC7,Q15904,O75503,P16615,P78417,Q9UI12,O60826,O95202,O75027,Q8N511,Q9Y487,P62942,O00203,P51572,P06576,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	521,263,265,21,150,160,431,38,165,417,317,313,182,57,305,72,341,329,330,211,90,358,97,473,238,250,381	473,1515,961,1455,2118,329,211,57,597,1359,628,330,1753,814,529,1213,160,250,2649,1810,417,21,3263,2946,817,1418,305,818,927,1141,2704,3140,2538,969,2581,3125,2498,999,38,2235,238,792,2236,2502,1098,97,72,1536,3101,2981,1227,263,2411,182,381,1011,1490,150,90,1604,1292,1196,803,265,431,828,2603,521,313,948,1126,165,1680,341,317,1623,358,1133,3137	0.7656032541864601,0.006307474011367515,0.3337574021162552,0.03437193328851483,-0.2826609847711293,1.0039634351651625,1.3855822269020739,2.8563508480242543,0.6171918880980484,0.09006522764362623,0.5920441322650274,1.0039634351651625,-0.1074347923116181,0.4385882859122563,0.6919219483408452,0.17253621044918402,1.7001874873242686,1.231854696356683,-0.6193116841420223,-0.1362485904097433,0.862258844628111,3.613683844728898,-1.5816442855181783,-0.9109430815275097,0.4385882859122563,0.062290731757696595,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.22681944749468783,-0.6509657620201212,-1.2187064928309388,-0.525427454868466,0.3337574021162552,-0.5565443734227432,-1.1836636419604167,-0.49448594888254555,0.30722341578558393,3.2574988008466623,-0.34234834725948426,1.2762487791777117,0.46447550012638145,-0.34234834725948426,-0.49448594888254555,0.25375565145434276,2.2759315653971224,2.59178502036956,0.006307474011367515,-1.1142272342228774,-0.9443136123937819,0.17253621044918402,1.187074181061587,-0.4331220969912666,1.5137692083085525,0.9335935466195544,0.30722341578558393,0.03437193328851483,1.7608315718187155,2.33000339930892,-0.02190402285820215,0.1451866537146581,0.19974671831673846,0.46447550012638145,1.187074181061587,0.862258844628111,0.4385882859122563,-0.5565443734227432,0.7165975954483155,1.0503522207387042,0.3601597156898264,0.25375565145434276,1.6388066898289295,-0.050263952997597124,1.0039634351651625,1.0503522207387042,-0.02190402285820215,0.9806125526787869,0.25375565145434276,-1.1836636419604167	3367
Abnormality of corneal stroma	7	17	2.815773979895209	0.0048659886598991	P16278,Q13510,P10619,P34913,O43505,P04062,O43933	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	5,101,40,181,87,56,92	87,92,56,40,5,898,650,181,900,2178,2072,101,188,3218,520,447,2042	2.3478963961729225,2.294021415669942,2.888427682882454,3.227809668601115,4.4292036485047825,0.38643153062342506,0.5667757956444454,1.5137692083085525,0.38643153062342506,-0.31242291199836886,-0.2530609609086133,2.2395519580884713,1.4926272539284748,-1.3972667312364715,0.7165975954483155,0.8382620619356581,-0.2236212584096826	3367
Transporter activity	49	144	2.810678206735689	0.0049437202923825	Q9NS69,P24539,O14925,Q15043,Q8WTV0,Q93050,O75964,P08183,O43676,Q13423,P45880,Q14849,Q99595,Q9Y277,P21796,Q9HD20,P41440,O43772,O60830,Q6NT16,Q9BSK2,P04062,P16615,Q8IXU6,P51798,P13073,Q70HW3,Q9UI12,Q9C0H2,P56385,Q8NE01,P30825,Q9H2D1,O95202,O75027,Q9Y487,Q9UBX3,P17900,Q9Y255,O15118,Q9HC21,Q6P4Q7,Q9UDW1,Q9P0J0,P12236,O15173,P06576,P30536,Q8TB61	Functions	GO Molecular function	msigdb_gomf	0,378,262,263,9,265,17,146,19,278,29,31,37,166,34,165,167,169,47,178,314,56,305,70,71,73,77,341,80,214,335,85,86,330,211,358,91,221,100,96,107,369,112,386,361,118,250,124,125	3092,2645,2756,1746,961,262,2328,96,118,963,19,1454,169,645,47,211,2758,2730,1261,508,851,17,2761,1876,3202,330,3054,545,2827,1361,718,56,1213,995,250,1697,1810,146,1091,1756,3263,2060,1215,1040,361,73,305,221,2896,927,819,548,2897,34,2002,378,1580,855,3141,124,85,3193,759,970,1366,2498,167,29,1889,2928,1528,511,3265,71,762,2834,1703,1590,553,2236,2296,214,3356,2502,2237,2008,934,1186,1223,278,936,1839,31,263,1433,1840,1539,3206,178,660,2192,369,77,70,1848,335,1604,125,9,698,265,875,1241,1300,37,470,3117,314,591,2479,400,80,622,880,86,1245,1972,1561,107,165,1509,0,386,91,112,743,341,677,1252,100,166,358,3137,920	-1.1142272342228774,-0.6193116841420223,-0.7148241860051961,-0.1074347923116181,0.3337574021162552,1.187074181061587,-0.40269627647094874,2.2759315653971224,2.0535377021037875,0.3337574021162552,3.735568419211056,0.03437193328851483,1.5974688426783576,0.5667757956444454,3.107165693020846,1.3855822269020739,-0.7148241860051961,-0.682802624960496,0.1451866537146581,0.7165975954483155,0.41257400595833643,3.867353512797234,-0.7148241860051961,-0.16521660034488708,-1.3611000187999303,1.0039634351651625,-1.0456406280505959,0.6671297810793578,-0.7794292005641262,0.09006522764362623,0.5158731784643796,2.888427682882454,0.17253621044918402,0.30722341578558393,1.231854696356683,-0.07877373131780484,-0.1362485904097433,1.7808852976154201,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,0.17253621044918402,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,1.3639014130956277,-0.8447967022235733,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,3.2722740469256966,-0.2236212584096826,0.9335935466195544,-0.02190402285820215,0.41257400595833643,-1.2187064928309388,1.9771403969263128,2.3834885282361222,-1.3251632411413339,0.490236763907363,0.3337574021162552,0.09006522764362623,-0.49448594888254555,1.6181799067894833,3.403217513344748,-0.16521660034488708,-0.8777714879158465,0.006307474011367515,0.7165975954483155,-1.5816442855181783,2.6256544201008225,0.490236763907363,-0.7794292005641262,-0.07877373131780484,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-3.3665191515672723,-0.49448594888254555,-0.34234834725948426,-0.2236212584096826,0.3601597156898264,0.19974671831673846,0.17253621044918402,1.1419011221151822,0.3601597156898264,-0.1362485904097433,3.3454673481684774,1.187074181061587,0.062290731757696595,-0.1362485904097433,0.006307474011367515,-1.3611000187999303,1.5348236972160396,0.5667757956444454,-0.31242291199836886,0.9571562106244959,2.5060688955133497,2.64250124049558,-0.1362485904097433,1.0039634351651625,-0.02190402285820215,1.9578570786990497,4.324586732934785,0.5413858311413456,1.187074181061587,0.41257400595833643,0.17253621044918402,0.1451866537146581,3.2722740469256966,0.7899351985641869,-1.1488380282478365,1.0503522207387042,0.6422200972561323,-0.4637180795900233,0.9099236880488443,2.4539090139419626,0.6171918880980484,0.41257400595833643,2.3657246319376566,0.17253621044918402,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,0.03437193328851483,4.803828948758111,0.9335935466195544,2.312045215706412,2.1287815015903986,0.5158731784643796,1.0039634351651625,0.5667757956444454,0.17253621044918402,2.2759315653971224,1.6388066898289295,0.9806125526787869,-1.1836636419604167,0.38643153062342506	3367
Carboxylic acid transport	12	29	2.799273275260618	0.0051217770818217	Q15041,P41440,P80404,O75746,P14174,O95563,P07602,P30825,Q9H2D1,Q9NZJ7,P53985,Q9UBX3	Processes and pathways	GO Biological process	msigdb_gobp	295,167,234,508,237,545,113,85,86,641,553,91	961,1517,508,1873,545,753,1877,113,1091,237,855,85,167,1590,553,2236,234,1223,1226,295,2188,1433,2192,86,1972,1561,641,91,677	0.3337574021162552,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.490236763907363,-0.16521660034488708,2.110076974296961,0.25375565145434276,1.2762487791777117,0.41257400595833643,2.3834885282361222,1.6181799067894833,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,1.2983027806935246,0.17253621044918402,0.17253621044918402,1.0963292676298746,-0.31242291199836886,0.062290731757696595,-0.31242291199836886,2.3657246319376566,-0.19434031752410985,0.006307474011367515,0.5920441322650274,2.312045215706412,0.5667757956444454	3367
Abnormal retinal artery morphology	7	20	2.77795309645446	0.0054702513868507	P16278,Q13510,P10619,Q9Y4P3,P07602,P21964,P17900	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	5,101,40,344,113,285,221	1257,2573,347,113,2649,40,2734,5,221,285,2539,2708,1472,101,1652,733,2552,641,1743,344	0.1451866537146581,-0.5565443734227432,0.9806125526787869,2.110076974296961,-0.6193116841420223,3.227809668601115,-0.682802624960496,4.4292036485047825,1.3639014130956277,1.1191654406700127,-0.525427454868466,-0.6509657620201212,0.03437193328851483,2.2395519580884713,-0.050263952997597124,0.5158731784643796,-0.525427454868466,0.5920441322650274,-0.07877373131780484,1.0039634351651625	3367
Endoplasmic reticulum lumen	16	59	2.7684017158762115	0.0056331973452481	P05067,Q14257,P30533,Q8TED1,O43852,Q86UP2,Q9Y680,P13667,Q96AY3,O95881,Q02818,Q07065,Q15084,Q9NZ08,O00584,Q9P2K2	Localization	GO Cellular component	msigdb_gocc	160,192,225,291,243,397,42,449,208,82,54,120,483,156,153,488	153,2328,3181,1454,243,2286,1628,628,82,160,599,3072,2733,449,786,629,1418,1634,1042,3076,2704,2538,1217,2581,1886,1044,225,1096,2501,1373,54,120,2071,481,1103,192,2593,483,1007,868,1106,1285,397,1603,1235,1965,291,3105,208,2603,1023,808,1730,1739,156,488,1075,1081,42	1.7406977485275759,-0.40269627647094874,-1.2894537744189682,0.03437193328851483,1.254099665260839,-0.3724389183184647,-0.050263952997597124,0.5920441322650274,2.418824969229302,1.7001874873242686,0.6171918880980484,-1.0798288811157457,-0.682802624960496,0.8141544886580385,0.46447550012638145,0.5920441322650274,0.062290731757696595,-0.050263952997597124,0.2805565672472788,-1.0798288811157457,-0.6509657620201212,-0.525427454868466,0.17253621044918402,-0.5565443734227432,-0.16521660034488708,0.2805565672472788,1.3421283755465698,0.25375565145434276,-0.49448594888254555,0.09006522764362623,2.9519476787527323,2.0154852262905982,-0.2530609609086133,0.7656032541864601,0.25375565145434276,1.471397176367932,-0.5565443734227432,0.7656032541864601,0.30722341578558393,0.41257400595833643,0.25375565145434276,0.1451866537146581,0.9099236880488443,-0.02190402285820215,0.17253621044918402,-0.19434031752410985,1.1191654406700127,-1.1142272342228774,1.407171519295945,-0.5565443734227432,0.30722341578558393,0.46447550012638145,-0.07877373131780484,-0.07877373131780484,1.7406977485275759,0.7656032541864601,0.2805565672472788,0.2805565672472788,3.197933935950603	3367
Organic acid transport	15	40	2.767284624077986	0.0056525381106515	Q15041,P41440,O43772,P80404,O75746,Q9UJS0,P31751,P23786,O95563,P14174,P08183,P30825,Q9H2D1,P53985,Q9UBX3	Processes and pathways	GO Biological process	msigdb_gobp	295,167,169,234,508,677,574,207,545,237,146,85,86,553,91	961,2328,169,645,1517,508,1873,545,1264,2798,753,1877,1575,146,1091,1215,237,207,855,1581,85,574,2175,167,1181,1590,553,2236,234,1223,1226,295,2188,1433,2192,86,1972,1561,91,677	0.3337574021162552,-0.40269627647094874,1.5974688426783576,0.5667757956444454,0.006307474011367515,0.7165975954483155,-0.16521660034488708,0.6671297810793578,0.1451866537146581,-0.7470323872777213,0.490236763907363,-0.16521660034488708,-0.02190402285820215,1.7808852976154201,0.25375565145434276,0.17253621044918402,1.2762487791777117,1.4286699849010147,0.41257400595833643,-0.02190402285820215,2.3834885282361222,0.6422200972561323,-0.31242291199836886,1.6181799067894833,0.19974671831673846,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,1.2983027806935246,0.17253621044918402,0.17253621044918402,1.0963292676298746,-0.31242291199836886,0.062290731757696595,-0.31242291199836886,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.312045215706412,0.5667757956444454	3367
Tetrapyrrole binding	9	18	2.766339342161259	0.0056689510142091	Q9H7Z7,Q16850,O43169,Q6UW02,P30519,P09601,O00264,O15173,Q8WUJ1	Functions	GO Molecular function	msigdb_gomf	65,131,39,200,16,21,304,118,312	304,1353,118,39,1756,21,996,16,363,131,200,312,3065,2745,523,65,3029,2918	1.0503522207387042,0.09006522764362623,2.0535377021037875,3.227809668601115,-0.1074347923116181,3.613683844728898,0.30722341578558393,3.9318663108151224,0.9571562106244959,1.9190660482263868,1.450078310745009,1.0503522207387042,-1.0456406280505959,-0.682802624960496,0.7165975954483155,2.742374563169135,-0.977885243317303,-0.8447967022235733	3367
Glycosylation	20	45	2.7630130883937825	0.0057270469887964	Q96L58,Q6ZXV5,Q10471,Q9BT22,Q10472,P04062,O75503,P46977,O60502,P04843,P04844,O43505,Q9H0U3,Q2TAA5,Q16706,Q86YN1,O15118,Q9UP83,Q08379,O60476	Processes and pathways	GO Biological process	msigdb_gobp	410,149,654,292,308,56,57,686,62,572,719,87,622,222,610,484,96,375,497,249	1800,96,709,87,249,62,2286,1572,2825,2615,57,2335,56,572,719,2228,686,3130,1826,1148,2012,497,654,308,2183,2074,610,222,149,1285,1286,484,908,410,2266,292,622,2157,1860,1739,1680,375,2789,1412,1989	-0.1362485904097433,2.2759315653971224,0.5158731784643796,2.3478963961729225,1.231854696356683,2.7588221406548605,-0.3724389183184647,-0.02190402285820215,-0.7794292005641262,-0.5878385067985065,2.8563508480242543,-0.40269627647094874,2.888427682882454,0.6422200972561323,0.5158731784643796,-0.34234834725948426,0.5413858311413456,-1.1836636419604167,-0.1362485904097433,0.22681944749468783,-0.2236212584096826,0.7411577066416265,0.5667757956444454,1.0503522207387042,-0.31242291199836886,-0.2530609609086133,0.6171918880980484,1.3639014130956277,1.7608315718187155,0.1451866537146581,0.1451866537146581,0.7656032541864601,0.38643153062342506,0.8861457519054411,-0.34234834725948426,1.1191654406700127,0.6171918880980484,-0.2826609847711293,-0.1362485904097433,-0.07877373131780484,-0.050263952997597124,0.9571562106244959,-0.7148241860051961,0.09006522764362623,-0.19434031752410985	3367
Liposaccharide metabolic process	7	16	2.75344377887901	0.0058971897989181	Q9H490,P06280,P16278,P04066,Q8NBX0,P04062,P17900	Processes and pathways	GO Biological process	msigdb_gobp	261,255,5,319,116,56,221	1572,56,319,255,347,2649,5,221,1224,1226,116,2312,1969,667,1069,261	-0.02190402285820215,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.6193116841420223,4.4292036485047825,1.3639014130956277,0.17253621044918402,0.17253621044918402,2.072455559506005,-0.3724389183184647,-0.19434031752410985,0.5667757956444454,0.2805565672472788,1.2095131214680288	3367
Active transmembrane transporter activity	15	59	2.735971239154471	0.0062196461772807	Q9HD20,P41440,Q15043,P51798,P13073,Q9UBX3,Q9UI12,Q9UDW1,P08183,O43676,P12236,O95202,O75027,P06576,P16615	Functions	GO Molecular function	msigdb_gomf	165,167,263,71,73,91,341,112,146,19,361,330,211,250,305	2645,1746,963,19,211,2758,2730,1261,1876,3202,330,3054,2827,718,1213,995,250,146,1091,1756,2060,1040,361,73,305,2896,927,819,548,2897,855,3141,3193,970,2498,167,1889,3265,71,762,1590,553,2236,2502,1186,1223,263,1433,1840,1539,1604,1972,165,1509,386,91,112,341,920	-0.6193116841420223,-0.1074347923116181,0.3337574021162552,3.735568419211056,1.3855822269020739,-0.7148241860051961,-0.682802624960496,0.1451866537146581,-0.16521660034488708,-1.3611000187999303,1.0039634351651625,-1.0456406280505959,-0.7794292005641262,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,1.7808852976154201,0.25375565145434276,-0.1074347923116181,-0.2530609609086133,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,-0.8447967022235733,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,0.41257400595833643,-1.2187064928309388,-1.3251632411413339,0.3337574021162552,-0.49448594888254555,1.6181799067894833,-0.16521660034488708,-1.5816442855181783,2.6256544201008225,0.490236763907363,-0.02190402285820215,0.6671297810793578,-0.34234834725948426,-0.49448594888254555,0.19974671831673846,0.17253621044918402,1.187074181061587,0.062290731757696595,-0.1362485904097433,0.006307474011367515,-0.02190402285820215,-0.19434031752410985,1.6388066898289295,0.03437193328851483,0.9335935466195544,2.312045215706412,2.1287815015903986,1.0039634351651625,0.38643153062342506	3367
Membrane lipid catabolic process	8	12	2.726767001663845	0.0063958184026104	Q99735,P06280,Q13510,P50897,P04066,P04062,O95470,P17900	Processes and pathways	GO Biological process	msigdb_gobp	260,255,101,38,319,56,123,221	123,56,319,255,347,2649,221,38,1224,101,260,1204	1.9771403969263128,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.6193116841420223,1.3639014130956277,3.2574988008466623,0.17253621044918402,2.2395519580884713,1.2095131214680288,0.19974671831673846	3367
Abnormality of head blood vessel	7	22	2.721317293465248	0.0065022317618967	P16278,Q13510,P10619,Q9Y4P3,P07602,P21964,P17900	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	5,101,40,344,113,285,221	1170,1257,2573,347,113,2649,40,2734,5,221,285,2539,1821,2708,1472,101,1652,733,2552,641,1743,344	0.19974671831673846,0.1451866537146581,-0.5565443734227432,0.9806125526787869,2.110076974296961,-0.6193116841420223,3.227809668601115,-0.682802624960496,4.4292036485047825,1.3639014130956277,1.1191654406700127,-0.525427454868466,-0.1362485904097433,-0.6509657620201212,0.03437193328851483,2.2395519580884713,-0.050263952997597124,0.5158731784643796,-0.525427454868466,0.5920441322650274,-0.07877373131780484,1.0039634351651625	3367
Intrinsic component of mitochondrial membrane	18	39	2.7094042607268025	0.0067404155338226	Q13505,Q6UXV4,Q99595,Q9H3K2,O14925,Q5XKP0,O75880,Q9HC21,O60830,O95563,Q9NX63,Q9UG56,Q9Y512,Q9BUR5,Q15070,Q9Y2R0,Q53H12,Q16891	Localization	GO Cellular component	msigdb_gocc	99,121,37,672,262,581,597,107,47,545,316,742,644,412,366,26,440,381	262,1455,47,2331,597,2761,545,1361,1040,3143,1181,1186,99,366,767,381,440,581,121,1289,2811,2632,1604,37,948,412,1555,672,1561,2480,107,1509,1310,316,742,1251,26,1133,644	1.187074181061587,0.03437193328851483,3.107165693020846,-0.40269627647094874,0.6171918880980484,-0.7148241860051961,0.6671297810793578,0.09006522764362623,0.2805565672472788,-1.2187064928309388,0.19974671831673846,0.19974671831673846,2.2759315653971224,0.9571562106244959,0.490236763907363,0.9335935466195544,0.8382620619356581,0.6422200972561323,2.0154852262905982,0.1451866537146581,-0.7470323872777213,-0.5878385067985065,-0.02190402285820215,3.2722740469256966,0.3601597156898264,0.8861457519054411,0.006307474011367515,0.5667757956444454,0.006307474011367515,-0.4637180795900233,2.165980585241542,0.03437193328851483,0.1451866537146581,1.0503522207387042,0.5158731784643796,0.17253621044918402,3.5306255572552185,0.25375565145434276,0.5920441322650274	3367
Secretory granule membrane	14	63	2.708295399391768	0.0067629797255897	P13473,P10321,Q93050,P10253,P30519,P42785,P07602,O00462,Q92542,Q07065,O95721,O15260,P27105,P35613	Localization	GO Cellular component	msigdb_gocc	161,229,265,269,16,18,113,180,218,120,122,60,157,286	304,180,2328,60,2118,1135,2489,2052,2490,1809,122,598,113,269,229,1039,816,161,3288,2340,1321,157,16,3125,1420,286,2228,18,1048,511,1182,2235,2835,2129,2130,3325,2239,3145,2011,120,2071,2873,1274,2074,691,2414,456,769,1012,1342,1293,218,265,2554,3117,1557,622,2159,641,1979,2483,1745,1414	1.0503522207387042,1.5137692083085525,-0.40269627647094874,2.775214074894696,-0.2826609847711293,0.22681944749468783,-0.49448594888254555,-0.2530609609086133,-0.49448594888254555,-0.1362485904097433,1.9963496087227715,0.6171918880980484,2.110076974296961,1.164537106940616,1.3202624041063196,0.2805565672472788,0.4385882859122563,1.679809873082842,-1.695207928870715,-0.40269627647094874,0.11769676093724667,1.7204832487252557,3.9318663108151224,-1.1836636419604167,0.062290731757696595,1.1191654406700127,-0.34234834725948426,3.8282095648532786,0.2805565672472788,0.7165975954483155,0.19974671831673846,-0.34234834725948426,-0.7794292005641262,-0.2826609847711293,-0.2826609847711293,-2.0500527607061283,-0.34234834725948426,-1.2187064928309388,-0.2236212584096826,2.0154852262905982,-0.2530609609086133,-0.8120166279085533,0.1451866537146581,-0.2530609609086133,0.5413858311413456,-0.4331220969912666,0.8141544886580385,0.490236763907363,0.30722341578558393,0.11769676093724667,0.1451866537146581,1.3855822269020739,1.187074181061587,-0.525427454868466,-1.1488380282478365,0.006307474011367515,0.6171918880980484,-0.2826609847711293,0.5920441322650274,-0.19434031752410985,-0.4637180795900233,-0.07877373131780484,0.09006522764362623	3367
Protein localization to mitochondrion	20	52	2.6910372752077047	0.0071230235629844	Q9NS69,O43615,O14925,P49840,O00170,P07900,Q5JRX3,Q99595,O60830,Q53H12,Q9Y276,O14737,P55786,O00203,P51572,Q9Y512,Q15070,P49257,Q9P0J0,P30536	Processes and pathways	GO Biological process	msigdb_gobp	0,376,262,512,268,648,658,37,47,440,342,205,93,473,238,644,366,496,386,124	268,473,747,205,262,376,47,2647,2761,2860,2732,2056,716,1361,648,1999,1577,3097,2226,2290,124,2442,1934,496,512,238,2446,93,2739,655,1226,366,1189,2018,440,658,1488,1196,1123,37,2102,1307,0,1073,386,2566,342,2887,1624,644,2755,919	1.164537106940616,0.7656032541864601,0.490236763907363,1.4286699849010147,1.187074181061587,0.9335935466195544,3.107165693020846,-0.6193116841420223,-0.7148241860051961,-0.8120166279085533,-0.682802624960496,-0.2530609609086133,0.5158731784643796,0.09006522764362623,0.5667757956444454,-0.2236212584096826,-0.02190402285820215,-1.1142272342228774,-0.34234834725948426,-0.3724389183184647,1.9771403969263128,-0.4637180795900233,-0.19434031752410985,0.7411577066416265,0.7165975954483155,1.2762487791777117,-0.4637180795900233,2.294021415669942,-0.682802624960496,0.5667757956444454,0.17253621044918402,0.9571562106244959,0.19974671831673846,-0.2236212584096826,0.8382620619356581,0.5667757956444454,0.03437193328851483,0.19974671831673846,0.25375565145434276,3.2722740469256966,-0.2530609609086133,0.1451866537146581,4.803828948758111,0.2805565672472788,0.9335935466195544,-0.525427454868466,1.0039634351651625,-0.8120166279085533,-0.02190402285820215,0.5920441322650274,-0.682802624960496,0.38643153062342506	3367
Circulatory system process	17	70	2.6710543794888006	0.0075613396055462	P42892,O75844,Q9UIQ6,P41440,P78417,P80404,P10253,P16615,P08183,P42785,P09601,P30825,Q99996,Q9HB40,Q9NZ08,Q16625,P48506	Processes and pathways	GO Biological process	msigdb_gobp	35,68,228,167,72,234,269,305,146,18,21,85,184,58,156,188,287	747,892,961,2286,1357,2223,68,1359,3328,1874,3182,529,2922,1212,1213,146,21,269,1215,1462,3162,3122,3288,305,927,3111,969,3125,85,167,2230,601,18,35,1368,287,633,512,1328,553,2236,2449,1098,72,234,2408,1828,3046,2245,2072,606,2981,1596,1227,2773,1433,188,2192,322,1720,2032,521,470,184,2785,58,1795,156,228,844	0.490236763907363,0.38643153062342506,0.3337574021162552,-0.3724389183184647,0.09006522764362623,-0.34234834725948426,2.6926945390869426,0.09006522764362623,-2.131961245664126,-0.16521660034488708,-1.2894537744189682,0.6919219483408452,-0.8777714879158465,0.17253621044918402,0.17253621044918402,1.7808852976154201,3.613683844728898,1.164537106940616,0.17253621044918402,0.03437193328851483,-1.2539690378581203,-1.1836636419604167,-1.695207928870715,1.0503522207387042,0.3601597156898264,-1.1488380282478365,0.3337574021162552,-1.1836636419604167,2.3834885282361222,1.6181799067894833,-0.34234834725948426,0.6171918880980484,3.8282095648532786,3.2722740469256966,0.09006522764362623,1.1191654406700127,0.5920441322650274,0.7165975954483155,0.11769676093724667,0.6671297810793578,-0.34234834725948426,-0.4637180795900233,0.25375565145434276,2.59178502036956,1.2983027806935246,-0.4331220969912666,-0.1362485904097433,-1.011660171259644,-0.34234834725948426,-0.2530609609086133,0.6171918880980484,-0.9443136123937819,-0.02190402285820215,0.17253621044918402,-0.7148241860051961,0.062290731757696595,1.4926272539284748,-0.31242291199836886,1.0272097103903832,-0.07877373131780484,-0.2236212584096826,0.7165975954483155,0.7899351985641869,1.5137692083085525,-0.7148241860051961,2.840232108692598,-0.1074347923116181,1.7406977485275759,1.3421283755465698,0.4385882859122563	3367
Neuromuscular process	6	26	2.6649442638112	0.0077001083666883	P05067,O75844,P78417,O14773,P04062,P17900	Processes and pathways	GO Biological process	msigdb_gobp	160,68,72,108,56,221	108,2051,2490,68,56,160,2649,269,1462,221,1815,969,601,1526,2232,1328,72,2666,865,2411,1777,1717,2367,907,1344,1026	2.1474158808446684,-0.2530609609086133,-0.49448594888254555,2.6926945390869426,2.888427682882454,1.7001874873242686,-0.6193116841420223,1.164537106940616,0.03437193328851483,1.3639014130956277,-0.1362485904097433,0.3337574021162552,0.6171918880980484,0.006307474011367515,-0.34234834725948426,0.11769676093724667,2.59178502036956,-0.6193116841420223,0.41257400595833643,-0.4331220969912666,-0.1074347923116181,-0.07877373131780484,-0.40269627647094874,0.38643153062342506,0.11769676093724667,0.30722341578558393	3367
Modified amino acid binding	7	25	2.6556202572526417	0.0079162702337178	Q99735,Q9H7Z7,Q14108,P41440,Q9BZF1,Q8WTV0,P00374	Functions	GO Molecular function	msigdb_gomf	260,65,6,167,400,9,63	2220,1927,63,1089,1697,1810,417,1757,2925,996,969,167,2126,2127,1938,2071,6,9,260,3117,400,65,1512,1984,2918	-0.34234834725948426,-0.19434031752410985,2.7588221406548605,0.25375565145434276,-0.07877373131780484,-0.1362485904097433,0.862258844628111,-0.1074347923116181,-0.8777714879158465,0.30722341578558393,0.3337574021162552,1.6181799067894833,-0.2826609847711293,-0.2826609847711293,-0.19434031752410985,-0.2530609609086133,4.383005400114565,4.324586732934785,1.2095131214680288,-1.1488380282478365,0.9099236880488443,2.742374563169135,0.03437193328851483,-0.19434031752410985,-0.8447967022235733	3367
Secondary alcohol metabolic process	14	43	2.653608076769922	0.0079636263370694	P05067,Q14739,Q9BQE5,Q16850,O15118,P49748,Q8WTV0,Q15392,Q15800,Q15125,P34913,P04062,Q9UBM7,Q14849	Processes and pathways	GO Biological process	msigdb_gobp	160,289,3,131,96,233,9,79,110,177,181,56,185,31	96,1872,2760,1808,3182,56,160,1632,1633,293,3348,181,1046,2125,2769,930,3252,233,3324,1763,2349,2660,2008,1534,3231,1050,1226,3019,938,289,31,2459,177,2985,79,2842,110,131,9,2992,3,185,1131	2.2759315653971224,-0.16521660034488708,-0.7148241860051961,-0.1362485904097433,-1.2894537744189682,2.888427682882454,1.7001874873242686,-0.050263952997597124,-0.050263952997597124,1.0963292676298746,-2.604267148830522,1.5137692083085525,0.2805565672472788,-0.2826609847711293,-0.7148241860051961,0.3601597156898264,-1.507173381664675,1.2983027806935246,-2.0500527607061283,-0.1074347923116181,-0.40269627647094874,-0.6193116841420223,-0.2236212584096826,0.006307474011367515,-1.4336660463047972,0.2805565672472788,0.17253621044918402,-0.977885243317303,0.3601597156898264,1.1191654406700127,3.3454673481684774,-0.4637180795900233,1.5348236972160396,-0.9443136123937819,2.471357400586925,-0.7794292005641262,2.1287815015903986,1.9190660482263868,4.324586732934785,-0.9443136123937819,4.54267192090626,1.5137692083085525,0.25375565145434276	3367
Ion homeostasis	30	97	2.640639098143354	0.0082749816133951	Q15043,Q93050,P30519,P09601,Q8IYU8,P48506,P05067,Q96A33,P50897,Q9HD20,Q9UJZ1,Q96TC7,Q15904,O75503,Q658P3,P16615,P78417,Q9UI12,Q8NE01,O60826,O95202,O75027,Q8N511,Q9Y487,P62942,P51572,Q6P4Q7,P06576,P30536,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	263,265,16,21,150,287,160,431,38,165,317,313,182,57,189,305,72,341,335,329,330,211,90,358,97,238,369,250,124,381	473,1515,961,1455,2118,329,211,57,597,1359,628,2616,330,1753,814,529,2922,1212,1213,160,250,2649,1810,417,21,1460,3263,2946,817,1418,305,818,927,1141,2704,3140,2538,969,2581,16,124,3125,2498,999,287,633,38,2235,238,792,2236,2502,1098,97,3216,72,1536,1947,3101,2013,2981,1476,1227,263,2411,182,381,189,369,1011,1490,150,1720,90,335,1604,1292,1196,803,265,431,828,2603,521,313,948,1126,2785,165,1680,341,317,1623,358,1133,844,3137	0.7656032541864601,0.006307474011367515,0.3337574021162552,0.03437193328851483,-0.2826609847711293,1.0039634351651625,1.3855822269020739,2.8563508480242543,0.6171918880980484,0.09006522764362623,0.5920441322650274,-0.5878385067985065,1.0039634351651625,-0.1074347923116181,0.4385882859122563,0.6919219483408452,-0.8777714879158465,0.17253621044918402,0.17253621044918402,1.7001874873242686,1.231854696356683,-0.6193116841420223,-0.1362485904097433,0.862258844628111,3.613683844728898,0.03437193328851483,-1.5816442855181783,-0.9109430815275097,0.4385882859122563,0.062290731757696595,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.22681944749468783,-0.6509657620201212,-1.2187064928309388,-0.525427454868466,0.3337574021162552,-0.5565443734227432,3.9318663108151224,1.9771403969263128,-1.1836636419604167,-0.49448594888254555,0.30722341578558393,1.1191654406700127,0.5920441322650274,3.2574988008466623,-0.34234834725948426,1.2762487791777117,0.46447550012638145,-0.34234834725948426,-0.49448594888254555,0.25375565145434276,2.2759315653971224,-1.3972667312364715,2.59178502036956,0.006307474011367515,-0.19434031752410985,-1.1142272342228774,-0.2236212584096826,-0.9443136123937819,0.03437193328851483,0.17253621044918402,1.187074181061587,-0.4331220969912666,1.5137692083085525,0.9335935466195544,1.4926272539284748,0.9571562106244959,0.30722341578558393,0.03437193328851483,1.7608315718187155,-0.07877373131780484,2.33000339930892,1.0039634351651625,-0.02190402285820215,0.1451866537146581,0.19974671831673846,0.46447550012638145,1.187074181061587,0.862258844628111,0.4385882859122563,-0.5565443734227432,0.7165975954483155,1.0503522207387042,0.3601597156898264,0.25375565145434276,-0.7148241860051961,1.6388066898289295,-0.050263952997597124,1.0039634351651625,1.0503522207387042,-0.02190402285820215,0.9806125526787869,0.25375565145434276,0.4385882859122563,-1.1836636419604167	3367
Aminoglycan metabolic process	7	13	2.6335054652888528	0.0084508475644593	P06865,P16278,P04066,P15586,P54802,Q7LGA3,O43505	Processes and pathways	GO Biological process	msigdb_gobp	347,5,319,198,109,239,87	87,1259,2055,319,347,2649,198,5,109,1535,2072,239,410	2.3478963961729225,0.1451866537146581,-0.2530609609086133,1.0272097103903832,0.9806125526787869,-0.6193116841420223,1.450078310745009,4.4292036485047825,2.1474158808446684,0.006307474011367515,-0.2530609609086133,1.2762487791777117,0.8861457519054411	3367
Organic acid transmembrane transporter activity	8	18	2.618003474502988	0.0088445904544001	P41440,O75746,O95563,P08183,P30825,Q9H2D1,P53985,Q9UBX3	Functions	GO Molecular function	msigdb_gomf	167,508,545,146,85,86,553,91	961,2328,508,545,146,1091,85,167,1590,553,1223,1433,2192,86,1972,1561,91,677	0.3337574021162552,-0.40269627647094874,0.7165975954483155,0.6671297810793578,1.7808852976154201,0.25375565145434276,2.3834885282361222,1.6181799067894833,-0.02190402285820215,0.6671297810793578,0.17253621044918402,0.062290731757696595,-0.31242291199836886,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.312045215706412,0.5667757956444454	3367
Transition metal ion homeostasis	9	24	2.597467488473928	0.0093914010251909	P05067,Q15043,P30519,O60826,P09601,Q15904,O75027,Q8N511,Q658P3	Processes and pathways	GO Biological process	msigdb_gobp	160,263,16,329,21,182,211,90,189	473,1515,1455,329,211,597,1359,529,2922,160,21,1141,16,3125,2498,2502,3101,2013,263,182,189,90,1126,358	0.7656032541864601,0.006307474011367515,0.03437193328851483,1.0039634351651625,1.3855822269020739,0.6171918880980484,0.09006522764362623,0.6919219483408452,-0.8777714879158465,1.7001874873242686,3.613683844728898,0.22681944749468783,3.9318663108151224,-1.1836636419604167,-0.49448594888254555,-0.49448594888254555,-1.1142272342228774,-0.2236212584096826,1.187074181061587,1.5137692083085525,1.4926272539284748,2.33000339930892,0.25375565145434276,0.9806125526787869	3367
Osteoarthritis	6	11	2.5864900514258333	0.0096958969350497	O75844,Q14108,Q8WVQ1,P51798,O00170,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	68,6,103,71,268,56	268,68,598,1522,56,71,6,821,103,281,564	1.164537106940616,2.6926945390869426,0.6171918880980484,0.006307474011367515,2.888427682882454,2.6256544201008225,4.383005400114565,0.4385882859122563,2.2029028392455228,1.1419011221151822,0.6671297810793578	3367
Cis golgi network	8	14	2.568076994358901	0.0102264439030022	P30533,P24390,Q86VS8,P49755,O00461,Q9NPR9,Q08379,Q99996	Localization	GO Cellular component	msigdb_gocc	225,2,264,511,51,52,497,184	51,1038,2,225,511,497,1479,610,264,909,1722,184,52,1917	2.983395828585835,0.2805565672472788,4.631429349052777,1.3421283755465698,0.7165975954483155,0.7411577066416265,0.03437193328851483,0.6171918880980484,1.187074181061587,0.38643153062342506,-0.07877373131780484,1.5137692083085525,2.9676974850627826,-0.16521660034488708	3367
Increased bone mineral density	10	29	2.5574861562754845	0.0105431754442488	Q14739,Q14108,Q15043,P51798,Q13126,P54802,Q15392,Q15125,P04062,Q14191	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,6,263,71,41,109,79,177,56,309	3190,2573,1522,56,898,650,3111,2400,2539,1821,71,109,3013,1472,2872,41,657,6,309,289,263,1652,177,79,2775,831,1743,3053,344	-1.3251632411413339,-0.5565443734227432,0.006307474011367515,2.888427682882454,0.38643153062342506,0.5667757956444454,-1.1488380282478365,-0.4331220969912666,-0.525427454868466,-0.1362485904097433,2.6256544201008225,2.1474158808446684,-0.977885243317303,0.03437193328851483,-0.8120166279085533,3.227809668601115,0.5667757956444454,4.383005400114565,1.0503522207387042,1.1191654406700127,1.187074181061587,-0.050263952997597124,1.5348236972160396,2.471357400586925,-0.7148241860051961,0.4385882859122563,-0.07877373131780484,-1.011660171259644,1.0039634351651625	3367
Abnormal delivery	6	20	2.5555546214286684	0.0106018720253684	Q9UBM7,O75844,P33991,Q9Y487,O43933,Q14191	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	185,68,140,358,92,309	1170,92,359,1628,68,3036,1522,853,2399,140,1096,1145,935,1148,309,613,1725,1308,185,358	0.19974671831673846,2.294021415669942,0.9571562106244959,-0.050263952997597124,2.6926945390869426,-1.011660171259644,0.006307474011367515,0.41257400595833643,-0.4331220969912666,1.820754742930303,0.25375565145434276,0.22681944749468783,0.3601597156898264,0.22681944749468783,1.0503522207387042,0.6171918880980484,-0.07877373131780484,0.1451866537146581,1.5137692083085525,0.9806125526787869	3367
Outer membrane	26	83	2.553864040437556	0.0106534846834092	Q9NS69,Q99720,P09601,Q99623,Q9BUR5,P45880,Q9Y277,P21796,O43169,Q92667,P50402,Q9NX63,Q96TC7,O00264,Q9UBM7,Q53H12,Q8WY22,Q13505,Q86UT6,O60313,Q9NQZ5,Q6UXV4,Q9NVT9,P30536,Q16891,Q8N2A8	Localization	GO Cellular component	msigdb_gocc	0,20,21,282,412,29,166,34,39,298,420,316,313,304,185,440,75,99,370,359,117,121,385,124,381,259	304,747,3360,39,359,1995,2793,2331,2761,1264,1361,3182,3006,2337,21,3097,34,124,2175,3143,601,1144,29,420,1181,2446,2447,3241,1188,99,2773,1189,381,440,2716,581,582,1282,121,1012,2675,370,1289,2811,2632,907,259,871,2957,1848,1116,75,298,1297,700,313,1442,282,20,2912,412,591,1555,2478,1788,2914,1403,117,0,461,1310,385,1621,1073,316,1204,641,185,1251,166,2887,644,919	1.0503522207387042,0.490236763907363,-5.050618198378846,3.227809668601115,0.9571562106244959,-0.2236212584096826,-0.7470323872777213,-0.40269627647094874,-0.7148241860051961,0.1451866537146581,0.09006522764362623,-1.2894537744189682,-0.977885243317303,-0.40269627647094874,3.613683844728898,-1.1142272342228774,3.2722740469256966,1.9771403969263128,-0.31242291199836886,-1.2187064928309388,0.6171918880980484,0.22681944749468783,3.403217513344748,0.862258844628111,0.19974671831673846,-0.4637180795900233,-0.4637180795900233,-1.4703006768417601,0.19974671831673846,2.2759315653971224,-0.7148241860051961,0.19974671831673846,0.9335935466195544,0.8382620619356581,-0.6509657620201212,0.6422200972561323,0.6422200972561323,0.1451866537146581,2.0154852262905982,0.30722341578558393,-0.6193116841420223,0.9571562106244959,0.1451866537146581,-0.7470323872777213,-0.5878385067985065,0.38643153062342506,1.2095131214680288,0.41257400595833643,-0.9109430815275097,-0.1362485904097433,0.25375565145434276,2.5405359673396357,1.07339179882247,0.1451866537146581,0.5413858311413456,1.0503522207387042,0.062290731757696595,1.1419011221151822,3.641045663369028,-0.8447967022235733,0.8861457519054411,0.6422200972561323,0.006307474011367515,-0.4637180795900233,-0.1074347923116181,-0.8447967022235733,0.09006522764362623,2.072455559506005,4.803828948758111,0.8141544886580385,0.1451866537146581,0.9335935466195544,-0.02190402285820215,0.2805565672472788,1.0503522207387042,0.19974671831673846,0.5920441322650274,1.5137692083085525,0.17253621044918402,1.6388066898289295,-0.8120166279085533,0.5920441322650274,0.38643153062342506	3367
Divalent inorganic cation homeostasis	16	46	2.547816223118522	0.0108399559317784	Q96A33,P05067,O95202,P62942,Q9HD20,Q15043,P78417,P09429,Q6P4Q7,Q9UJZ1,P51572,Q8NE01,Q96TC7,Q8IYU8,P16615,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	431,160,330,97,165,263,72,417,369,317,238,335,313,150,305,381	473,1515,2118,628,330,1753,160,2649,1810,417,817,1418,305,818,927,3140,2538,969,3125,999,238,1098,97,72,1947,2981,1227,263,2411,381,369,1011,1490,150,335,1604,1292,1196,431,2603,313,948,165,317,1623,1133	0.7656032541864601,0.006307474011367515,-0.2826609847711293,0.5920441322650274,1.0039634351651625,-0.1074347923116181,1.7001874873242686,-0.6193116841420223,-0.1362485904097433,0.862258844628111,0.4385882859122563,0.062290731757696595,1.0503522207387042,0.4385882859122563,0.3601597156898264,-1.2187064928309388,-0.525427454868466,0.3337574021162552,-1.1836636419604167,0.30722341578558393,1.2762487791777117,0.25375565145434276,2.2759315653971224,2.59178502036956,-0.19434031752410985,-0.9443136123937819,0.17253621044918402,1.187074181061587,-0.4331220969912666,0.9335935466195544,0.9571562106244959,0.30722341578558393,0.03437193328851483,1.7608315718187155,1.0039634351651625,-0.02190402285820215,0.1451866537146581,0.19974671831673846,0.862258844628111,-0.5565443734227432,1.0503522207387042,0.3601597156898264,1.6388066898289295,1.0503522207387042,-0.02190402285820215,0.25375565145434276	3367
Passive transmembrane transporter activity	7	25	2.525701464093113	0.0115467555326214	Q9Y277,P21796,P51798,Q9C0H2,O75964,P56385,P45880	Functions	GO Molecular function	msigdb_gomf	166,34,71,80,17,214,29	2756,851,17,1361,250,1697,1810,3263,34,378,1580,759,2498,29,2928,71,2296,214,2237,1604,698,591,80,166,3137	-0.7148241860051961,0.41257400595833643,3.867353512797234,0.09006522764362623,1.231854696356683,-0.07877373131780484,-0.1362485904097433,-1.5816442855181783,3.2722740469256966,0.9335935466195544,-0.02190402285820215,0.490236763907363,-0.49448594888254555,3.403217513344748,-0.8777714879158465,2.6256544201008225,-0.3724389183184647,1.3855822269020739,-0.34234834725948426,-0.02190402285820215,0.5413858311413456,0.6422200972561323,2.4539090139419626,1.6388066898289295,-1.1836636419604167	3367
Protein targeting to mitochondrion	17	40	2.515883327013561	0.0118734481363058	Q9NS69,Q5JRX3,O43615,Q99595,O14925,P49840,Q9P0J0,O60830,O14737,P51572,O00170,Q9Y512,P49257,Q53H12,P07900,P30536,P55786	Processes and pathways	GO Biological process	msigdb_gobp	0,658,376,37,262,512,386,47,205,238,268,644,496,440,648,124,93	268,205,262,376,47,2647,2761,2860,2732,2056,716,1361,648,1999,2226,124,1934,496,512,238,93,2739,655,1226,1189,2018,440,658,1488,1123,37,2102,1307,0,386,2566,2887,1624,644,2755	1.164537106940616,1.4286699849010147,1.187074181061587,0.9335935466195544,3.107165693020846,-0.6193116841420223,-0.7148241860051961,-0.8120166279085533,-0.682802624960496,-0.2530609609086133,0.5158731784643796,0.09006522764362623,0.5667757956444454,-0.2236212584096826,-0.34234834725948426,1.9771403969263128,-0.19434031752410985,0.7411577066416265,0.7165975954483155,1.2762487791777117,2.294021415669942,-0.682802624960496,0.5667757956444454,0.17253621044918402,0.19974671831673846,-0.2236212584096826,0.8382620619356581,0.5667757956444454,0.03437193328851483,0.25375565145434276,3.2722740469256966,-0.2530609609086133,0.1451866537146581,4.803828948758111,0.9335935466195544,-0.525427454868466,-0.8120166279085533,-0.02190402285820215,0.5920441322650274,-0.682802624960496	3367
Cellular response to biotic stimulus	16	36	2.513656712822549	0.0119486678262699	Q96A33,O75844,P26583,Q9NUQ9,Q8WTV0,Q8N7H5,Q86UE4,P11802,P09429,Q9Y263,P04637,P14174,P08670,P51617,P30536,O76024	Processes and pathways	GO Biological process	msigdb_gobp	431,68,294,136,9,694,171,573,417,173,479,237,390,307,124,628	1171,68,628,1574,479,390,417,1462,573,237,2439,294,2704,2581,124,3078,1368,2234,307,2931,728,2248,1656,1109,2082,1111,171,694,9,1784,431,2200,1403,136,1863,173	0.19974671831673846,2.6926945390869426,0.5920441322650274,-0.02190402285820215,0.7656032541864601,0.9099236880488443,0.862258844628111,0.03437193328851483,0.6422200972561323,1.2762487791777117,-0.4637180795900233,1.0963292676298746,-0.6509657620201212,-0.5565443734227432,1.9771403969263128,-1.0798288811157457,0.09006522764362623,-0.34234834725948426,1.0503522207387042,-0.8777714879158465,0.5158731784643796,-0.34234834725948426,-0.050263952997597124,0.25375565145434276,-0.2530609609086133,0.25375565145434276,1.5974688426783576,0.5413858311413456,4.324586732934785,-0.1074347923116181,0.862258844628111,-0.31242291199836886,0.09006522764362623,1.8799723150528511,-0.1362485904097433,1.5974688426783576	3367
Sphingolipid biosynthetic process	6	16	2.5120495605660724	0.0120032230180822	Q13510,Q96G23,Q06136,P04062,Q53H12,O95470	Processes and pathways	GO Biological process	msigdb_gobp	101,43,142,56,440,123	448,1317,123,56,2002,756,1224,142,1226,101,440,43,1069,1204,704,1979	0.8141544886580385,0.11769676093724667,1.9771403969263128,2.888427682882454,-0.2236212584096826,0.490236763907363,0.17253621044918402,1.820754742930303,0.17253621044918402,2.2395519580884713,0.8382620619356581,3.1829254312869844,0.2805565672472788,0.19974671831673846,0.5413858311413456,-0.19434031752410985	3367
Pigment granule	19	59	2.509323371912877	0.0120962692827335	Q93050,P49755,P57088,P50991,P02786,O75955,P27105,P35613,P55209,P41440,P21281,P04843,P13667,Q92542,Q15084,P07237,O14773,O43852,O00560	Localization	GO Cellular component	msigdb_gocc	265,511,393,392,529,528,157,286,164,167,548,572,449,218,483,599,108,243,625	625,108,243,1807,528,529,572,1213,1877,599,1697,648,1810,1091,754,2337,1757,1215,1039,449,1418,1758,548,3076,3224,157,1217,1886,1044,857,286,167,1938,511,392,1822,1182,2235,792,164,393,1098,2665,2131,2239,1944,1535,1227,2593,483,2247,1433,2508,1852,218,1117,265,1499,1985	0.5920441322650274,2.1474158808446684,1.254099665260839,-0.1362485904097433,0.6919219483408452,0.6919219483408452,0.6422200972561323,0.17253621044918402,-0.16521660034488708,0.6171918880980484,-0.07877373131780484,0.5667757956444454,-0.1362485904097433,0.25375565145434276,0.490236763907363,-0.40269627647094874,-0.1074347923116181,0.17253621044918402,0.2805565672472788,0.8141544886580385,0.062290731757696595,-0.1074347923116181,0.6671297810793578,-1.0798288811157457,-1.4336660463047972,1.7204832487252557,0.17253621044918402,-0.16521660034488708,0.2805565672472788,0.41257400595833643,1.1191654406700127,1.6181799067894833,-0.19434031752410985,0.7165975954483155,0.9099236880488443,-0.1362485904097433,0.19974671831673846,-0.34234834725948426,0.46447550012638145,1.6388066898289295,0.9099236880488443,0.25375565145434276,-0.6193116841420223,-0.2826609847711293,-0.34234834725948426,-0.19434031752410985,0.006307474011367515,0.17253621044918402,-0.5565443734227432,0.7656032541864601,-0.34234834725948426,0.062290731757696595,-0.49448594888254555,-0.1362485904097433,1.3855822269020739,0.25375565145434276,1.187074181061587,0.03437193328851483,-0.19434031752410985	3367
Slc mediated transmembrane transport	8	19	2.5076237153257748	0.0121546024609979	Q15043,Q70HW3,Q99808,P30825,P12236,Q8TB61,Q9UBX3,P35613	Processes and pathways	Reactome Pathways	msigdb_reactome	263,77,470,85,361,125,91,286	995,1091,1215,1040,361,3125,85,286,1637,553,2236,263,1433,2192,77,125,470,1972,91	0.30722341578558393,0.25375565145434276,0.17253621044918402,0.2805565672472788,0.9571562106244959,-1.1836636419604167,2.3834885282361222,1.1191654406700127,-0.050263952997597124,0.6671297810793578,-0.34234834725948426,1.187074181061587,0.062290731757696595,-0.31242291199836886,2.5060688955133497,1.9578570786990497,0.7899351985641869,-0.19434031752410985,2.312045215706412	3367
Glycosphingolipid metabolism	7	15	2.5012676855429063	0.0123749602639522	P06280,P16278,Q13510,P10619,P07602,P04062,P17900	Processes and pathways	Reactome Pathways	msigdb_reactome	255,5,101,40,113,56,221	680,1454,56,255,347,113,2649,40,1634,5,221,101,3256,1204,641	0.5413858311413456,0.03437193328851483,2.888427682882454,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,3.227809668601115,-0.050263952997597124,4.4292036485047825,1.3639014130956277,2.2395519580884713,-1.507173381664675,0.19974671831673846,0.5920441322650274	3367
Cellular transition metal ion homeostasis	10	20	2.4986839894630517	0.0124655414702354	P05067,Q8N511,O00203,Q15043,Q9Y487,O60826,P09601,Q15904,O75027,P02786	Processes and pathways	GO Biological process	msigdb_gobp	160,90,473,263,358,329,21,182,211,529	473,1515,1455,329,211,597,1359,529,160,21,1141,3125,2498,2502,3101,263,182,90,1126,358	0.7656032541864601,0.006307474011367515,0.03437193328851483,1.0039634351651625,1.3855822269020739,0.6171918880980484,0.09006522764362623,0.6919219483408452,1.7001874873242686,3.613683844728898,0.22681944749468783,-1.1836636419604167,-0.49448594888254555,-0.49448594888254555,-1.1142272342228774,1.187074181061587,1.5137692083085525,2.33000339930892,0.25375565145434276,0.9806125526787869	3367
Contractures of the joints of the upper limbs	19	80	2.4968693426389	0.0125295112876964	Q99720,Q9NR77,Q96L58,P42892,Q9BYW2,P16435,Q8IZA0,Q99741,O75844,Q71SY5,Q15392,P23786,Q96AY3,P35637,O43933,Q8WVQ1,Q9UP83,Q7LGA3,Q9UJX6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	20,148,410,35,432,293,172,327,68,78,79,207,208,332,92,103,375,239,254	781,892,1800,1170,711,3190,92,1356,2286,1136,2332,68,1808,1173,1522,853,1462,293,898,3111,2702,207,1419,2581,2402,332,2125,2176,1820,35,1326,1821,420,1328,2178,2661,1146,1707,1148,3260,797,1476,728,821,2302,2188,79,2254,1599,3218,1845,78,239,537,172,1851,103,1116,2680,2470,208,410,1157,2960,1300,20,327,808,432,837,1792,3027,148,254,2042,375,1411,1168,2433,1035	0.46447550012638145,0.38643153062342506,-0.1362485904097433,0.19974671831673846,0.5158731784643796,-1.3251632411413339,2.294021415669942,0.09006522764362623,-0.3724389183184647,0.22681944749468783,-0.40269627647094874,2.6926945390869426,-0.1362485904097433,0.19974671831673846,0.006307474011367515,0.41257400595833643,0.03437193328851483,1.0963292676298746,0.38643153062342506,-1.1488380282478365,-0.6509657620201212,1.4286699849010147,0.062290731757696595,-0.5565443734227432,-0.4331220969912666,1.0039634351651625,-0.2826609847711293,-0.31242291199836886,-0.1362485904097433,3.2722740469256966,0.11769676093724667,-0.1362485904097433,0.862258844628111,0.11769676093724667,-0.31242291199836886,-0.6193116841420223,0.22681944749468783,-0.07877373131780484,0.22681944749468783,-1.5442869665963095,0.46447550012638145,0.03437193328851483,0.5158731784643796,0.4385882859122563,-0.3724389183184647,-0.31242291199836886,2.471357400586925,-0.34234834725948426,-0.02190402285820215,-1.3972667312364715,-0.1362485904097433,2.4887438961354635,1.2762487791777117,0.6919219483408452,1.5974688426783576,-0.1362485904097433,2.2029028392455228,0.25375565145434276,-0.6193116841420223,-0.4637180795900233,1.407171519295945,0.8861457519054411,0.22681944749468783,-0.9109430815275097,0.1451866537146581,3.641045663369028,1.0272097103903832,0.46447550012638145,0.862258844628111,0.4385882859122563,-0.1074347923116181,-0.977885243317303,1.7808852976154201,1.231854696356683,-0.2236212584096826,0.9571562106244959,0.09006522764362623,0.22681944749468783,-0.4331220969912666,0.30722341578558393	3367
Abnormal vascular physiology	13	58	2.4854606483906325	0.0129383890982079	P05067,Q14739,P06280,O75844,Q14108,P51798,Q8IZA0,Q9UMS0,Q71SY5,P04062,P51617,Q9NZ08,Q5T2R2	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	160,289,255,68,6,71,172,302,78,56,307,156,223	892,3181,2573,2286,2894,2759,68,1631,2827,718,598,1522,56,479,160,255,2733,2399,819,3111,1580,2538,2706,1818,2539,2230,2126,1938,307,71,762,1330,1472,1148,2980,3101,6,2983,289,1652,223,3188,1903,660,78,172,1236,828,876,2752,156,447,2999,1743,302,1983,344,2918	0.38643153062342506,-1.2894537744189682,-0.5565443734227432,-0.3724389183184647,-0.8447967022235733,-0.7148241860051961,2.6926945390869426,-0.050263952997597124,-0.7794292005641262,0.5158731784643796,0.6171918880980484,0.006307474011367515,2.888427682882454,0.7656032541864601,1.7001874873242686,1.2095131214680288,-0.682802624960496,-0.4331220969912666,0.4385882859122563,-1.1488380282478365,-0.02190402285820215,-0.525427454868466,-0.6509657620201212,-0.1362485904097433,-0.525427454868466,-0.34234834725948426,-0.2826609847711293,-0.19434031752410985,1.0503522207387042,2.6256544201008225,0.490236763907363,0.11769676093724667,0.03437193328851483,0.22681944749468783,-0.9443136123937819,-1.1142272342228774,4.383005400114565,-0.9443136123937819,1.1191654406700127,-0.050263952997597124,1.3639014130956277,-1.2894537744189682,-0.16521660034488708,0.5667757956444454,2.4887438961354635,1.5974688426783576,0.17253621044918402,0.4385882859122563,0.41257400595833643,-0.682802624960496,1.7406977485275759,0.8382620619356581,-0.9443136123937819,-0.07877373131780484,1.07339179882247,-0.19434031752410985,1.0039634351651625,-0.8447967022235733	3367
Glycerophospholipid metabolic process	14	59	2.4725650178574075	0.0134147309638013	Q9H490,P35790,Q9BZF1,O15228,Q92604,Q8WTV0,Q96N66,Q8NCC3,Q6IAN0,Q9UJZ1,Q99623,Q8N2K0,Q9NPH0,O95674	Processes and pathways	GO Biological process	msigdb_gobp	261,256,400,474,398,9,137,10,517,317,282,442,88,436	3158,892,2858,474,2892,1572,1264,436,3287,2120,2439,818,2582,1759,256,1819,1525,1526,1821,1328,1707,655,1379,2014,517,1961,585,1115,442,518,10,1342,872,9,2551,1392,398,2312,1969,1440,137,805,667,2719,1158,282,1070,987,1732,913,400,1162,261,88,1309,1204,742,317,1079	-1.2539690378581203,0.38643153062342506,-0.8120166279085533,0.7656032541864601,-0.8447967022235733,-0.02190402285820215,0.1451866537146581,0.8382620619356581,-1.695207928870715,-0.2826609847711293,-0.4637180795900233,0.4385882859122563,-0.5565443734227432,-0.1074347923116181,1.2095131214680288,-0.1362485904097433,0.006307474011367515,0.006307474011367515,-0.1362485904097433,0.11769676093724667,-0.07877373131780484,0.5667757956444454,0.09006522764362623,-0.2236212584096826,0.7165975954483155,-0.19434031752410985,0.6422200972561323,0.25375565145434276,0.8382620619356581,0.7165975954483155,4.301006972369739,0.11769676093724667,0.41257400595833643,4.324586732934785,-0.525427454868466,0.09006522764362623,0.9099236880488443,-0.3724389183184647,-0.19434031752410985,0.062290731757696595,1.8603105982788577,0.46447550012638145,0.5667757956444454,-0.6509657620201212,0.22681944749468783,1.1419011221151822,0.2805565672472788,0.3337574021162552,-0.07877373131780484,0.38643153062342506,0.9099236880488443,0.22681944749468783,1.2095131214680288,2.3478963961729225,0.1451866537146581,0.19974671831673846,0.5158731784643796,1.0503522207387042,0.2805565672472788	3367
Mitochondrial calcium ion transport	7	16	2.4698593533042046	0.0135166183563664	Q9Y277,P21796,Q92667,Q9UJZ1,Q99623,Q8IYU8,P45880	Processes and pathways	Reactome Pathways	msigdb_reactome	166,34,298,317,282,150,29	2647,330,34,2707,29,655,150,1604,1196,298,522,282,948,317,166,1133	-0.6193116841420223,1.0039634351651625,3.2722740469256966,-0.6509657620201212,3.403217513344748,0.5667757956444454,1.7608315718187155,-0.02190402285820215,0.19974671831673846,1.07339179882247,0.7165975954483155,1.1419011221151822,0.3601597156898264,1.0503522207387042,1.6388066898289295,0.25375565145434276	3367
Abnormality of femur morphology	33	73	2.4696430749305582	0.0135247922017742	P06280,Q92889,P16278,Q8NCM8,Q96HY6,Q96L58,Q99575,Q9NUQ7,Q96A33,Q14739,P16435,Q96HA7,O00754,Q9NZC9,Q9H3U1,P04062,Q99741,O75844,P04066,P51798,O00116,Q14807,Q96AY3,Q9BXW9,Q9Y487,O95831,Q8WVQ1,P38398,P04637,Q7LGA3,P07602,Q9NZJ7,Q9UHX1	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	255,520,5,801,281,410,806,564,431,289,293,831,543,447,838,56,327,68,319,71,571,821,208,879,358,716,103,723,479,239,113,641,127	571,892,1800,543,1170,2218,2286,3004,2331,2332,1628,68,2797,716,2120,1522,56,319,479,255,3055,113,1462,5,293,3111,2537,2581,723,3143,1527,1326,1180,71,1097,2869,2236,1704,289,821,1651,868,1715,1844,3296,239,1544,801,2198,103,520,431,208,831,281,410,2266,806,327,879,2638,838,1860,564,1202,447,641,127,2042,1411,2386,358,2919	0.6422200972561323,0.38643153062342506,-0.1362485904097433,0.6671297810793578,0.19974671831673846,-0.34234834725948426,-0.3724389183184647,-0.977885243317303,-0.40269627647094874,-0.40269627647094874,-0.050263952997597124,2.6926945390869426,-0.7470323872777213,0.5158731784643796,-0.2826609847711293,0.006307474011367515,2.888427682882454,1.0272097103903832,0.7656032541864601,1.2095131214680288,-1.0456406280505959,2.110076974296961,0.03437193328851483,4.4292036485047825,1.0963292676298746,-1.1488380282478365,-0.525427454868466,-0.5565443734227432,0.5158731784643796,-1.2187064928309388,0.006307474011367515,0.11769676093724667,0.19974671831673846,2.6256544201008225,0.25375565145434276,-0.8120166279085533,-0.34234834725948426,-0.07877373131780484,1.1191654406700127,0.4385882859122563,-0.050263952997597124,0.41257400595833643,-0.07877373131780484,-0.1362485904097433,-1.7335697222803168,1.2762487791777117,0.006307474011367515,0.46447550012638145,-0.31242291199836886,2.2029028392455228,0.7165975954483155,0.862258844628111,1.407171519295945,0.4385882859122563,1.1419011221151822,0.8861457519054411,-0.34234834725948426,0.46447550012638145,1.0272097103903832,0.41257400595833643,-0.5878385067985065,0.4385882859122563,-0.1362485904097433,0.6671297810793578,0.19974671831673846,0.8382620619356581,0.5920441322650274,1.9578570786990497,-0.2236212584096826,0.09006522764362623,-0.40269627647094874,0.9806125526787869,-0.8447967022235733	3367
Glycosaminoglycan metabolism	7	12	2.4654652158841044	0.013683546041147	P06865,P16278,P15586,P54802,Q7LGA3,O43505,Q8TB61	Processes and pathways	Reactome Pathways	msigdb_reactome	347,5,198,109,239,87,125	922,87,596,347,2649,198,5,109,239,125,410,1680	0.3601597156898264,2.3478963961729225,0.6171918880980484,0.9806125526787869,-0.6193116841420223,1.450078310745009,4.4292036485047825,2.1474158808446684,1.2762487791777117,1.9578570786990497,0.8861457519054411,-0.050263952997597124	3367
Proton transporting two sector atpase complex	8	20	2.4650465436348994	0.0136995454824082	Q93050,P06576,Q9UI12,O75964,P56385,Q15904,Q9Y487,Q8N511	Localization	GO Cellular component	msigdb_gocc	265,250,341,17,214,182,358,90	851,17,250,548,2897,378,1580,759,970,2498,2928,2296,214,2502,182,90,265,947,341,358	0.41257400595833643,3.867353512797234,1.231854696356683,0.6671297810793578,-0.8447967022235733,0.9335935466195544,-0.02190402285820215,0.490236763907363,0.3337574021162552,-0.49448594888254555,-0.8777714879158465,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,1.5137692083085525,2.33000339930892,1.187074181061587,0.3601597156898264,1.0039634351651625,0.9806125526787869	3367
Mitochondrial membrane organization	21	42	2.4573551472034665	0.0139964242748851	Q9NS69,Q9H3K2,P49840,Q9BUR5,P45880,P48506,Q9NX63,Q53H12,Q5XKP0,Q9Y276,O14737,O95202,Q13505,O00203,P04637,O60313,Q9Y512,Q15070,Q6UXV4,Q9P0J0,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	0,672,512,412,29,287,316,440,581,342,205,330,99,473,479,359,644,366,121,386,381	473,205,359,2331,2761,330,479,995,648,2337,1040,3240,2290,1934,3143,2769,29,287,512,2234,2446,99,366,381,2018,440,581,121,1289,2811,2632,1196,412,672,0,1310,316,386,342,1133,644,2755	0.7656032541864601,1.4286699849010147,0.9571562106244959,-0.40269627647094874,-0.7148241860051961,1.0039634351651625,0.7656032541864601,0.30722341578558393,0.5667757956444454,-0.40269627647094874,0.2805565672472788,-1.4703006768417601,-0.3724389183184647,-0.19434031752410985,-1.2187064928309388,-0.7148241860051961,3.403217513344748,1.1191654406700127,0.7165975954483155,-0.34234834725948426,-0.4637180795900233,2.2759315653971224,0.9571562106244959,0.9335935466195544,-0.2236212584096826,0.8382620619356581,0.6422200972561323,2.0154852262905982,0.1451866537146581,-0.7470323872777213,-0.5878385067985065,0.19974671831673846,0.8861457519054411,0.5667757956444454,4.803828948758111,0.1451866537146581,1.0503522207387042,0.9335935466195544,1.0039634351651625,0.25375565145434276,0.5920441322650274,-0.682802624960496	3367
Ion transmembrane transport	40	135	2.441651317092498	0.014620259891964	Q15043,O75964,P08183,Q99623,Q8IYU8,Q13423,P45880,P27105,P05067,Q9Y277,P21796,Q9HD20,P41440,Q15041,O43772,Q9UJZ1,Q9UHG3,Q99996,P16615,O75844,P51798,P78417,P13073,Q70HW3,Q9UI12,Q9C0H2,P56385,P30825,Q9H2D1,P35754,O95202,O75027,Q9UBX3,P62942,Q9HC21,Q6P4Q7,Q9UDW1,P12236,P06576,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	263,17,146,282,150,278,29,157,160,166,34,165,167,295,169,317,48,184,305,68,71,72,73,77,341,80,214,85,86,213,330,211,91,97,107,369,112,361,250,125	2756,1746,961,1085,169,645,2118,1517,211,3200,2758,2793,2647,508,68,1873,851,17,330,545,2575,718,1213,160,995,1877,250,1697,1879,1810,146,1091,1756,3263,2060,1632,1040,361,73,305,818,927,819,548,2897,3111,34,378,1580,157,3140,969,3240,3125,85,3193,213,759,970,2498,167,999,29,419,1047,1889,2928,1145,71,1590,553,1824,792,2236,2296,214,2502,2237,1098,97,72,1186,1223,974,1273,863,1947,278,764,2981,1476,1839,295,263,2411,1433,369,1011,77,1490,150,1720,1604,125,1196,698,875,2603,521,3314,282,184,948,591,80,622,86,2785,1972,1561,107,165,2207,91,112,1680,48,341,677,317,166,1033,1452,1133,3137	-0.7148241860051961,-0.1074347923116181,0.3337574021162552,0.25375565145434276,1.5974688426783576,0.5667757956444454,-0.2826609847711293,0.006307474011367515,1.3855822269020739,-1.3611000187999303,-0.7148241860051961,-0.7470323872777213,-0.6193116841420223,0.7165975954483155,2.6926945390869426,-0.16521660034488708,0.41257400595833643,3.867353512797234,1.0039634351651625,0.6671297810793578,-0.5565443734227432,0.5158731784643796,0.17253621044918402,1.7001874873242686,0.30722341578558393,-0.16521660034488708,1.231854696356683,-0.07877373131780484,-0.16521660034488708,-0.1362485904097433,1.7808852976154201,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,-0.050263952997597124,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,-1.1488380282478365,3.2722740469256966,0.9335935466195544,-0.02190402285820215,1.7204832487252557,-1.2187064928309388,0.3337574021162552,-1.4703006768417601,-1.1836636419604167,2.3834885282361222,-1.3251632411413339,1.3855822269020739,0.490236763907363,0.3337574021162552,-0.49448594888254555,1.6181799067894833,0.30722341578558393,3.403217513344748,0.862258844628111,0.2805565672472788,-0.16521660034488708,-0.8777714879158465,0.22681944749468783,2.6256544201008225,-0.02190402285820215,0.6671297810793578,-0.1362485904097433,0.46447550012638145,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.25375565145434276,2.2759315653971224,2.59178502036956,0.19974671831673846,0.17253621044918402,0.3337574021162552,0.1451866537146581,0.41257400595833643,-0.19434031752410985,1.1419011221151822,0.490236763907363,-0.9443136123937819,0.03437193328851483,-0.1362485904097433,1.0963292676298746,1.187074181061587,-0.4331220969912666,0.062290731757696595,0.9571562106244959,0.30722341578558393,2.5060688955133497,0.03437193328851483,1.7608315718187155,-0.07877373131780484,-0.02190402285820215,1.9578570786990497,0.19974671831673846,0.5413858311413456,0.41257400595833643,-0.5565443734227432,0.7165975954483155,-1.929324312075685,1.1419011221151822,1.5137692083085525,0.3601597156898264,0.6422200972561323,2.4539090139419626,0.6171918880980484,2.3657246319376566,-0.7148241860051961,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,-0.31242291199836886,2.312045215706412,2.1287815015903986,-0.050263952997597124,3.107165693020846,1.0039634351651625,0.5667757956444454,1.0503522207387042,1.6388066898289295,0.30722341578558393,0.062290731757696595,0.25375565145434276,-1.1836636419604167	3367
Endoplasmic reticulum organization	10	38	2.426592366022992	0.0152413700537745	Q96A33,Q15041,Q9NQC3,Q15629,Q00765,P57088,O95197,Q9P2W9,P49257,P46379	Processes and pathways	GO Biological process	msigdb_gobp	431,295,106,11,515,393,46,81,496,30	680,526,747,1870,1315,1454,1992,1360,46,1753,30,496,393,2129,2237,515,975,795,1480,295,2188,11,2307,1106,2505,1658,1547,1066,1156,431,3256,1125,1305,2159,106,1204,1979,81	0.5413858311413456,0.6919219483408452,0.490236763907363,-0.16521660034488708,0.11769676093724667,0.03437193328851483,-0.2236212584096826,0.09006522764362623,3.122414185082993,-0.1074347923116181,3.3454673481684774,0.7411577066416265,0.9099236880488443,-0.2826609847711293,-0.34234834725948426,0.7165975954483155,0.3337574021162552,0.46447550012638145,0.03437193328851483,1.0963292676298746,-0.31242291199836886,4.156903668614397,-0.3724389183184647,0.25375565145434276,-0.49448594888254555,-0.050263952997597124,0.006307474011367515,0.2805565672472788,0.22681944749468783,0.862258844628111,-1.507173381664675,0.25375565145434276,0.1451866537146581,-0.2826609847711293,2.1844760833621826,0.19974671831673846,-0.19434031752410985,2.436398337597714	3367
Mitochondrial protein import	15	30	2.421574086160188	0.0154534506805923	Q9NS69,Q5JRX3,Q13505,O43615,Q99595,P21796,O14925,O75746,Q9UJS0,Q9Y276,O60830,Q9NX63,Q9Y512,P12236,P06576	Processes and pathways	Reactome Pathways	msigdb_reactome	0,658,99,376,37,34,262,508,677,342,47,316,644,361,250	262,376,47,3201,2331,2647,508,2761,1361,250,1756,1999,1040,361,34,1580,3143,655,99,2018,658,37,2992,1307,0,316,677,342,644,2755	1.187074181061587,0.9335935466195544,3.107165693020846,-1.3611000187999303,-0.40269627647094874,-0.6193116841420223,0.7165975954483155,-0.7148241860051961,0.09006522764362623,1.231854696356683,-0.1074347923116181,-0.2236212584096826,0.2805565672472788,0.9571562106244959,3.2722740469256966,-0.02190402285820215,-1.2187064928309388,0.5667757956444454,2.2759315653971224,-0.2236212584096826,0.5667757956444454,3.2722740469256966,-0.9443136123937819,0.1451866537146581,4.803828948758111,1.0503522207387042,0.5667757956444454,1.0039634351651625,0.5920441322650274,-0.682802624960496	3367
Phospholipid binding	24	96	2.4115203300966543	0.0158861661540066	Q9H490,Q14108,Q9BZF1,Q8WTV0,Q8NCC3,Q9UM22,P53367,P53365,P45880,P21796,P50897,P09429,O60749,Q9UJZ1,Q9Y4G8,O14964,Q9H4A6,Q13045,Q9Y5X1,Q641Q2,O14773,O60313,Q15075,P07602	Functions	GO Molecular function	msigdb_gomf	261,6,400,9,10,13,141,147,29,34,38,417,416,317,59,434,471,216,492,368,108,359,367,113	680,781,1869,892,625,108,434,1924,709,2219,359,3221,416,2489,753,1697,113,3191,1810,417,2289,1757,2061,1321,34,2002,2441,3012,2975,29,2293,1048,1528,38,1822,147,141,934,935,2071,1225,2456,216,2013,1274,1709,6,1538,1949,2459,367,2247,2906,368,942,1601,1015,1193,10,2263,9,1722,2312,2032,2959,500,3117,1499,3256,1555,400,2425,1791,880,261,471,2379,1795,2520,641,1164,1566,3177,317,1512,1864,13,3106,1252,643,705,2889,1984,59,492,844	0.5413858311413456,0.46447550012638145,-0.16521660034488708,0.38643153062342506,0.5920441322650274,2.1474158808446684,0.8382620619356581,-0.19434031752410985,0.5158731784643796,-0.34234834725948426,0.9571562106244959,-1.4336660463047972,0.862258844628111,-0.49448594888254555,0.490236763907363,-0.07877373131780484,2.110076974296961,-1.3251632411413339,-0.1362485904097433,0.862258844628111,-0.3724389183184647,-0.1074347923116181,-0.2530609609086133,0.11769676093724667,3.2722740469256966,-0.2236212584096826,-0.4637180795900233,-0.977885243317303,-0.9443136123937819,3.403217513344748,-0.3724389183184647,0.2805565672472788,0.006307474011367515,3.2574988008466623,-0.1362485904097433,1.7808852976154201,1.820754742930303,0.3601597156898264,0.3601597156898264,-0.2530609609086133,0.17253621044918402,-0.4637180795900233,1.3855822269020739,-0.2236212584096826,0.1451866537146581,-0.07877373131780484,4.383005400114565,0.006307474011367515,-0.19434031752410985,-0.4637180795900233,0.9571562106244959,-0.34234834725948426,-0.8447967022235733,0.9571562106244959,0.3601597156898264,-0.02190402285820215,0.30722341578558393,0.19974671831673846,4.301006972369739,-0.34234834725948426,4.324586732934785,-0.07877373131780484,-0.3724389183184647,-0.2236212584096826,-0.9109430815275097,0.7411577066416265,-1.1488380282478365,0.03437193328851483,-1.507173381664675,0.006307474011367515,0.9099236880488443,-0.4331220969912666,-0.1074347923116181,0.41257400595833643,1.2095131214680288,0.7899351985641869,-0.40269627647094874,-0.1074347923116181,-0.49448594888254555,0.5920441322650274,0.22681944749468783,0.006307474011367515,-1.2539690378581203,1.0503522207387042,0.03437193328851483,-0.1362485904097433,4.144687074033624,-1.1142272342228774,0.17253621044918402,0.5920441322650274,0.5413858311413456,-0.8120166279085533,-0.19434031752410985,2.840232108692598,0.7656032541864601,0.4385882859122563	3367
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	9	17	2.4045088746054257	0.0161942130105448	P05067,P14314,Q13217,P07237,Q86UP2,Q02818,O43852,Q15084,Q07065	Processes and pathways	Reactome Pathways	msigdb_reactome	160,629,481,599,397,54,243,483,120	243,628,160,599,2733,629,1418,1042,54,120,2071,481,483,1007,1106,397,1730	1.254099665260839,0.5920441322650274,1.7001874873242686,0.6171918880980484,-0.682802624960496,0.5920441322650274,0.062290731757696595,0.2805565672472788,2.9519476787527323,2.0154852262905982,-0.2530609609086133,0.7656032541864601,0.7656032541864601,0.30722341578558393,0.25375565145434276,0.9099236880488443,-0.07877373131780484	3367
Signaling receptor regulator activity	6	14	2.4006686806965445	0.0163651462903855	P05067,P30533,P43490,P26583,Q9UMX5,P14174	Functions	GO Molecular function	msigdb_gomf	160,225,257,294,45,237	160,1090,417,237,2340,294,225,257,2006,2406,1373,1895,1847,45	1.7001874873242686,0.25375565145434276,0.862258844628111,1.2762487791777117,-0.40269627647094874,1.0963292676298746,1.3421283755465698,1.2095131214680288,-0.2236212584096826,-0.4331220969912666,0.09006522764362623,-0.16521660034488708,-0.1362485904097433,3.137614127937716	3367
Vacuolar membrane	26	116	2.3986337172923475	0.016456366789652	Q14108,Q15043,Q8WTV0,Q93050,P42785,P27105,Q14849,P13473,P42892,P41440,P10619,O00462,P04062,O75503,O15260,Q16625,P11117,P51798,Q92542,Q8N511,O15118,Q9UIQ6,P07602,Q07065,O95721,P20645	Localization	GO Cellular component	msigdb_gocc	6,263,9,265,18,157,31,161,35,167,40,180,56,57,60,188,69,71,218,90,96,228,113,120,122,251	473,180,1515,96,60,1805,626,3275,1318,1172,2489,2052,57,528,1809,122,2055,56,719,1697,113,1810,1091,754,2336,1214,269,40,69,1757,1039,161,251,548,2897,2702,157,857,757,970,2498,2228,167,601,18,35,2622,1182,2235,71,1269,3081,1183,2544,2130,2502,3310,2133,2770,1535,2838,120,3046,863,1894,2014,6,31,263,188,769,441,428,90,1342,1493,9,1782,2466,218,265,828,2554,1608,2935,3024,875,1344,700,3173,3117,987,1557,1558,703,622,1858,1614,3118,2207,2916,2787,641,1979,567,1164,341,228,2043,3157,678,1745,918,2887,358,3180	0.7656032541864601,1.5137692083085525,0.006307474011367515,2.2759315653971224,2.775214074894696,-0.1362485904097433,0.5920441322650274,-1.6192482414532234,0.11769676093724667,0.19974671831673846,-0.49448594888254555,-0.2530609609086133,2.8563508480242543,0.6919219483408452,-0.1362485904097433,1.9963496087227715,-0.2530609609086133,2.888427682882454,0.5158731784643796,-0.07877373131780484,2.110076974296961,-0.1362485904097433,0.25375565145434276,0.490236763907363,-0.40269627647094874,0.17253621044918402,1.164537106940616,3.227809668601115,2.64250124049558,-0.1074347923116181,0.2805565672472788,1.679809873082842,1.231854696356683,0.6671297810793578,-0.8447967022235733,-0.6509657620201212,1.7204832487252557,0.41257400595833643,0.490236763907363,0.3337574021162552,-0.49448594888254555,-0.34234834725948426,1.6181799067894833,0.6171918880980484,3.8282095648532786,3.2722740469256966,-0.5878385067985065,0.19974671831673846,-0.34234834725948426,2.6256544201008225,0.1451866537146581,-1.0798288811157457,0.19974671831673846,-0.525427454868466,-0.2826609847711293,-0.49448594888254555,-1.889636471997411,-0.2826609847711293,-0.7148241860051961,0.006307474011367515,-0.7794292005641262,2.0154852262905982,-1.011660171259644,0.41257400595833643,-0.16521660034488708,-0.2236212584096826,4.383005400114565,3.3454673481684774,1.187074181061587,1.4926272539284748,0.490236763907363,0.8382620619356581,0.862258844628111,2.33000339930892,0.11769676093724667,0.03437193328851483,4.324586732934785,-0.1074347923116181,-0.4637180795900233,1.3855822269020739,1.187074181061587,0.4385882859122563,-0.525427454868466,-0.02190402285820215,-0.8777714879158465,-0.977885243317303,0.41257400595833643,0.11769676093724667,0.5413858311413456,-1.2539690378581203,-1.1488380282478365,0.3337574021162552,0.006307474011367515,0.006307474011367515,0.5413858311413456,0.6171918880980484,-0.1362485904097433,-0.02190402285820215,-1.1488380282478365,-0.31242291199836886,-0.8447967022235733,-0.7148241860051961,0.5920441322650274,-0.19434031752410985,0.6671297810793578,0.22681944749468783,1.0039634351651625,1.3421283755465698,-0.2236212584096826,-1.2187064928309388,0.5667757956444454,-0.07877373131780484,0.38643153062342506,-0.8120166279085533,0.9806125526787869,-1.2539690378581203	3367
Iron uptake and transport	8	18	2.3803765182329117	0.0172949564064206	Q93050,Q9UI12,P30519,P09601,Q15904,Q9Y487,P02786,Q658P3	Processes and pathways	Reactome Pathways	msigdb_reactome	265,341,16,21,182,358,529,189	1359,529,21,548,2897,1141,16,970,2498,2502,1184,2669,182,189,1779,265,341,358	0.09006522764362623,0.6919219483408452,3.613683844728898,0.6671297810793578,-0.8447967022235733,0.22681944749468783,3.9318663108151224,0.3337574021162552,-0.49448594888254555,-0.49448594888254555,0.19974671831673846,-0.6193116841420223,1.5137692083085525,1.4926272539284748,-0.1074347923116181,1.187074181061587,1.0039634351651625,0.9806125526787869	3367
Iron ion homeostasis	7	18	2.3393668763955677	0.0193164542825183	Q15043,P30519,P09601,Q15904,O75027,Q8N511,Q658P3	Processes and pathways	GO Biological process	msigdb_gobp	263,16,21,182,211,90,189	211,1359,529,2922,21,1141,16,3125,2498,2502,3101,2013,263,182,189,90,1126,358	1.3855822269020739,0.09006522764362623,0.6919219483408452,-0.8777714879158465,3.613683844728898,0.22681944749468783,3.9318663108151224,-1.1836636419604167,-0.49448594888254555,-0.49448594888254555,-1.1142272342228774,-0.2236212584096826,1.187074181061587,1.5137692083085525,1.4926272539284748,2.33000339930892,0.25375565145434276,0.9806125526787869	3367
Active ion transmembrane transporter activity	10	32	2.336744775802228	0.019452458844972	Q9HD20,P41440,P51798,Q15043,P13073,Q9UI12,Q9UDW1,O95202,P06576,P16615	Functions	GO Molecular function	msigdb_gomf	165,167,71,263,73,341,112,330,250,305	330,718,1213,995,250,1091,1756,2060,1040,361,73,305,927,819,548,2897,3193,970,2498,167,1889,71,1590,2236,2502,1186,1223,263,1972,165,112,341	1.0039634351651625,0.5158731784643796,0.17253621044918402,0.30722341578558393,1.231854696356683,0.25375565145434276,-0.1074347923116181,-0.2530609609086133,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,-1.3251632411413339,0.3337574021162552,-0.49448594888254555,1.6181799067894833,-0.16521660034488708,2.6256544201008225,-0.02190402285820215,-0.34234834725948426,-0.49448594888254555,0.19974671831673846,0.17253621044918402,1.187074181061587,-0.19434031752410985,1.6388066898289295,2.1287815015903986,1.0039634351651625	3367
Cellular response to molecule of bacterial origin	9	29	2.334829533361435	0.0195523277131439	P26583,Q9NUQ9,Q8WTV0,Q86UE4,Q9Y263,P14174,P08670,P51617,P30536	Processes and pathways	GO Biological process	msigdb_gobp	294,136,9,171,173,237,390,307,124	1171,1574,390,417,1462,573,237,2439,294,2704,2581,124,3078,1368,307,2931,2248,1656,1109,2082,1111,171,694,9,1784,2200,136,1863,173	0.19974671831673846,-0.02190402285820215,0.9099236880488443,0.862258844628111,0.03437193328851483,0.6422200972561323,1.2762487791777117,-0.4637180795900233,1.0963292676298746,-0.6509657620201212,-0.5565443734227432,1.9771403969263128,-1.0798288811157457,0.09006522764362623,1.0503522207387042,-0.8777714879158465,-0.34234834725948426,-0.050263952997597124,0.25375565145434276,-0.2530609609086133,0.25375565145434276,1.5974688426783576,0.5413858311413456,4.324586732934785,-0.1074347923116181,-0.31242291199836886,1.8799723150528511,-0.1362485904097433,1.5974688426783576	3367
Cell surface	24	74	2.3347453077829936	0.0195567298547718	Q8WTV0,P08183,P04439,Q99623,P02786,O75955,P05067,P42892,P41440,P09429,P55899,Q8TCT9,Q12846,P26038,P13667,O96005,P30533,Q13641,P10321,O15258,P01889,P07237,P14174,P06576	Localization	GO Cellular component	msigdb_gocc	9,146,389,282,529,528,160,35,167,417,422,201,452,451,449,220,225,607,229,475,598,599,237,250	1685,475,750,596,2490,528,220,3005,598,529,753,389,160,1877,250,3006,599,1697,146,1091,754,755,417,2289,229,1999,1577,1039,816,449,237,1930,2439,2340,1042,1580,451,2538,1886,1044,225,2707,167,35,2540,1938,3186,1824,422,2548,1101,2071,452,1895,975,1947,2013,1274,607,3244,1103,1596,1954,2021,201,9,2032,282,1023,1247,2321,1623,1984,3137	-0.07877373131780484,0.7656032541864601,0.490236763907363,0.6171918880980484,-0.49448594888254555,0.6919219483408452,1.3639014130956277,-0.977885243317303,0.6171918880980484,0.6919219483408452,0.490236763907363,0.9099236880488443,1.7001874873242686,-0.16521660034488708,1.231854696356683,-0.977885243317303,0.6171918880980484,-0.07877373131780484,1.7808852976154201,0.25375565145434276,0.490236763907363,0.490236763907363,0.862258844628111,-0.3724389183184647,1.3202624041063196,-0.2236212584096826,-0.02190402285820215,0.2805565672472788,0.4385882859122563,0.8141544886580385,1.2762487791777117,-0.19434031752410985,-0.4637180795900233,-0.40269627647094874,0.2805565672472788,-0.02190402285820215,0.8141544886580385,-0.525427454868466,-0.16521660034488708,0.2805565672472788,1.3421283755465698,-0.6509657620201212,1.6181799067894833,3.2722740469256966,-0.525427454868466,-0.19434031752410985,-1.2894537744189682,-0.1362485904097433,0.862258844628111,-0.525427454868466,0.25375565145434276,-0.2530609609086133,0.8141544886580385,-0.16521660034488708,0.3337574021162552,-0.19434031752410985,-0.2236212584096826,0.1451866537146581,0.6171918880980484,-1.4703006768417601,0.25375565145434276,-0.02190402285820215,-0.19434031752410985,-0.2236212584096826,1.450078310745009,4.324586732934785,-0.2236212584096826,1.1419011221151822,0.30722341578558393,0.17253621044918402,-0.3724389183184647,-0.02190402285820215,-0.19434031752410985,-1.1836636419604167	3367
Regulation of lipid metabolic process	16	53	2.3324000634723943	0.0196796547776225	O75844,Q13510,P16435,Q92604,Q96N66,Q8WTV0,Q2T9J0,Q96G23,P49748,Q9UJZ1,P07602,Q99623,P34913,Q9UBM7,O60869,P30536	Processes and pathways	GO Biological process	msigdb_gobp	68,101,293,398,137,9,395,43,233,317,113,282,181,185,210,124	3360,1927,210,2731,68,2760,1808,1264,2168,753,1213,113,573,293,2439,124,574,181,723,601,233,1181,3339,2449,2008,689,2838,1224,1226,101,1379,2014,2075,425,1008,395,3188,769,1342,872,9,398,1609,43,137,1158,282,641,185,1680,1409,317,2967	-5.050618198378846,-0.19434031752410985,1.3855822269020739,-0.682802624960496,2.6926945390869426,-0.7148241860051961,-0.1362485904097433,0.1451866537146581,-0.31242291199836886,0.490236763907363,0.17253621044918402,2.110076974296961,0.6422200972561323,1.0963292676298746,-0.4637180795900233,1.9771403969263128,0.6422200972561323,1.5137692083085525,0.5158731784643796,0.6171918880980484,1.2983027806935246,0.19974671831673846,-2.428078853113266,-0.4637180795900233,-0.2236212584096826,0.5413858311413456,-0.7794292005641262,0.17253621044918402,0.17253621044918402,2.2395519580884713,0.09006522764362623,-0.2236212584096826,-0.2530609609086133,0.862258844628111,0.30722341578558393,0.9099236880488443,-1.2894537744189682,0.490236763907363,0.11769676093724667,0.41257400595833643,4.324586732934785,0.9099236880488443,-0.02190402285820215,3.1829254312869844,1.8603105982788577,0.22681944749468783,1.1419011221151822,0.5920441322650274,1.5137692083085525,-0.050263952997597124,0.09006522764362623,1.0503522207387042,-0.9109430815275097	3367
Cristae formation	8	19	2.3302876122744616	0.0197909550476285	P24539,Q13505,O75964,P56385,Q9NX63,Q6UXV4,P06576,Q16891	Processes and pathways	Reactome Pathways	msigdb_reactome	378,99,17,214,316,121,250,381	2331,851,17,250,378,1580,759,3143,2928,2296,214,99,381,581,121,412,1310,316,644	-0.40269627647094874,0.41257400595833643,3.867353512797234,1.231854696356683,0.9335935466195544,-0.02190402285820215,0.490236763907363,-1.2187064928309388,-0.8777714879158465,-0.3724389183184647,1.3855822269020739,2.2759315653971224,0.9335935466195544,0.6422200972561323,2.0154852262905982,0.8861457519054411,0.1451866537146581,1.0503522207387042,0.5920441322650274	3367
Cation transmembrane transport	27	104	2.316139866761832	0.0205506331871971	Q15043,O75964,Q99623,Q8IYU8,Q13423,P27105,P05067,P21796,Q9HD20,O43772,Q9UJZ1,Q99996,P16615,P78417,P13073,Q70HW3,Q9UI12,P56385,P30825,P35754,O95202,O75027,P62942,Q9HC21,Q6P4Q7,Q9UDW1,P06576	Processes and pathways	GO Biological process	msigdb_gobp	263,17,282,150,278,157,160,34,165,169,317,184,305,72,73,77,341,214,85,213,330,211,97,107,369,112,250	1746,961,1085,169,2118,211,2758,2793,2647,851,17,330,2575,718,1213,160,995,1877,250,1697,1879,1810,1091,1756,2060,1632,1040,73,305,818,927,819,548,2897,3111,34,378,1580,157,3140,969,3240,3125,85,3193,213,759,970,2498,999,419,1047,1889,2928,1145,1824,792,2236,2296,214,2502,2237,1098,97,72,1186,974,1273,863,1947,278,2981,1476,263,2411,1433,369,1011,77,1490,150,1720,1604,1196,698,875,2603,521,3314,282,184,948,622,2785,1972,1561,107,165,112,1680,341,317,1033,1133	-0.1074347923116181,0.3337574021162552,0.25375565145434276,1.5974688426783576,-0.2826609847711293,1.3855822269020739,-0.7148241860051961,-0.7470323872777213,-0.6193116841420223,0.41257400595833643,3.867353512797234,1.0039634351651625,-0.5565443734227432,0.5158731784643796,0.17253621044918402,1.7001874873242686,0.30722341578558393,-0.16521660034488708,1.231854696356683,-0.07877373131780484,-0.16521660034488708,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-0.2530609609086133,-0.050263952997597124,0.2805565672472788,2.5747617035953736,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,-1.1488380282478365,3.2722740469256966,0.9335935466195544,-0.02190402285820215,1.7204832487252557,-1.2187064928309388,0.3337574021162552,-1.4703006768417601,-1.1836636419604167,2.3834885282361222,-1.3251632411413339,1.3855822269020739,0.490236763907363,0.3337574021162552,-0.49448594888254555,0.30722341578558393,0.862258844628111,0.2805565672472788,-0.16521660034488708,-0.8777714879158465,0.22681944749468783,-0.1362485904097433,0.46447550012638145,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.25375565145434276,2.2759315653971224,2.59178502036956,0.19974671831673846,0.3337574021162552,0.1451866537146581,0.41257400595833643,-0.19434031752410985,1.1419011221151822,-0.9443136123937819,0.03437193328851483,1.187074181061587,-0.4331220969912666,0.062290731757696595,0.9571562106244959,0.30722341578558393,2.5060688955133497,0.03437193328851483,1.7608315718187155,-0.07877373131780484,-0.02190402285820215,0.19974671831673846,0.5413858311413456,0.41257400595833643,-0.5565443734227432,0.7165975954483155,-1.929324312075685,1.1419011221151822,1.5137692083085525,0.3601597156898264,0.6171918880980484,-0.7148241860051961,-0.19434031752410985,0.006307474011367515,2.165980585241542,1.6388066898289295,2.1287815015903986,-0.050263952997597124,1.0039634351651625,1.0503522207387042,0.30722341578558393,0.25375565145434276	3367
Abnormality of humoral immunity	26	60	2.304164346602387	0.0212134197700526	P40763,Q14108,Q9UJS0,P09601,P02786,P13051,P19447,P48506,Q96HA7,O00754,Q9NZC9,Q15904,P04062,P51617,P28070,Q96AX1,Q13043,P26038,Q9H0U3,Q9UJW0,P04637,P42345,P14174,Q6PGP7,Q13546,Q15833	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	632,6,677,21,529,649,650,287,831,543,447,182,56,307,306,828,690,451,622,104,479,601,237,770,764,380	543,2051,2335,1574,1522,529,56,479,21,2652,3121,649,237,967,898,2399,650,2925,3111,451,2400,306,2899,632,601,287,1938,1530,2977,307,1049,2709,904,1050,1224,690,764,2183,6,2460,380,182,770,871,1969,828,831,2316,2423,622,1562,990,447,677,104,1745,2789,1081,1988,2919	0.6671297810793578,-0.2530609609086133,-0.40269627647094874,-0.02190402285820215,0.006307474011367515,0.6919219483408452,2.888427682882454,0.7656032541864601,3.613683844728898,-0.6193116841420223,-1.1836636419604167,0.5667757956444454,1.2762487791777117,0.3337574021162552,0.38643153062342506,-0.4331220969912666,0.5667757956444454,-0.8777714879158465,-1.1488380282478365,0.8141544886580385,-0.4331220969912666,1.0503522207387042,-0.8447967022235733,0.5920441322650274,0.6171918880980484,1.1191654406700127,-0.19434031752410985,0.006307474011367515,-0.9443136123937819,1.0503522207387042,0.2805565672472788,-0.6509657620201212,0.38643153062342506,0.2805565672472788,0.17253621044918402,0.5413858311413456,0.490236763907363,-0.31242291199836886,4.383005400114565,-0.4637180795900233,0.9335935466195544,1.5137692083085525,0.490236763907363,0.41257400595833643,-0.19434031752410985,0.4385882859122563,0.4385882859122563,-0.3724389183184647,-0.4331220969912666,0.6171918880980484,0.006307474011367515,0.3337574021162552,0.8382620619356581,0.5667757956444454,2.2029028392455228,-0.07877373131780484,-0.7148241860051961,0.2805565672472788,-0.19434031752410985,-0.8447967022235733	3367
Inorganic ion transmembrane transport	25	99	2.2885565328664854	0.0221051318806635	Q15043,O75964,Q99623,Q8IYU8,Q13423,P27105,P21796,Q9HD20,Q9UJZ1,Q9UHG3,Q99996,P16615,P51798,P78417,P13073,Q9UI12,P56385,P35754,O95202,O75027,Q9UBX3,P62942,Q6P4Q7,Q9UDW1,P06576	Processes and pathways	GO Biological process	msigdb_gobp	263,17,282,150,278,157,34,165,317,48,184,305,71,72,73,341,214,213,330,211,91,97,369,112,250	1746,961,1085,2118,211,2758,2793,2647,851,17,330,2575,718,1213,995,1877,250,1697,1810,1091,1756,2060,1632,1040,73,305,818,927,819,548,2897,3111,34,378,1580,157,3140,969,3240,3125,3193,213,759,970,2498,999,419,1047,1889,2928,1145,71,1824,792,2236,2296,214,2502,2237,1098,97,72,1186,1223,974,1273,863,1947,278,2981,1476,263,369,1011,1490,150,1720,1604,1196,698,875,2603,521,3314,282,184,948,622,2785,1972,165,91,112,1680,48,341,317,1033,1133	-0.1074347923116181,0.3337574021162552,0.25375565145434276,-0.2826609847711293,1.3855822269020739,-0.7148241860051961,-0.7470323872777213,-0.6193116841420223,0.41257400595833643,3.867353512797234,1.0039634351651625,-0.5565443734227432,0.5158731784643796,0.17253621044918402,0.30722341578558393,-0.16521660034488708,1.231854696356683,-0.07877373131780484,-0.1362485904097433,0.25375565145434276,-0.1074347923116181,-0.2530609609086133,-0.050263952997597124,0.2805565672472788,2.5747617035953736,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,-1.1488380282478365,3.2722740469256966,0.9335935466195544,-0.02190402285820215,1.7204832487252557,-1.2187064928309388,0.3337574021162552,-1.4703006768417601,-1.1836636419604167,-1.3251632411413339,1.3855822269020739,0.490236763907363,0.3337574021162552,-0.49448594888254555,0.30722341578558393,0.862258844628111,0.2805565672472788,-0.16521660034488708,-0.8777714879158465,0.22681944749468783,2.6256544201008225,-0.1362485904097433,0.46447550012638145,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,-0.34234834725948426,0.25375565145434276,2.2759315653971224,2.59178502036956,0.19974671831673846,0.17253621044918402,0.3337574021162552,0.1451866537146581,0.41257400595833643,-0.19434031752410985,1.1419011221151822,-0.9443136123937819,0.03437193328851483,1.187074181061587,0.9571562106244959,0.30722341578558393,0.03437193328851483,1.7608315718187155,-0.07877373131780484,-0.02190402285820215,0.19974671831673846,0.5413858311413456,0.41257400595833643,-0.5565443734227432,0.7165975954483155,-1.929324312075685,1.1419011221151822,1.5137692083085525,0.3601597156898264,0.6171918880980484,-0.7148241860051961,-0.19434031752410985,1.6388066898289295,2.312045215706412,2.1287815015903986,-0.050263952997597124,3.107165693020846,1.0039634351651625,1.0503522207387042,0.30722341578558393,0.25375565145434276	3367
SNARE protein	7	8	2.2817980666596807	0.0225012649893587	O15400,Q86Y82,Q12846,O43752,Q9P2W9,Q13190,O95721	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	626,459,452,206,81,365,122	626,206,122,452,365,459,81,678	0.5920441322650274,1.4286699849010147,1.9963496087227715,0.8141544886580385,0.9571562106244959,0.8141544886580385,2.436398337597714,0.5667757956444454	3367
SNARE protein	7	8	2.2817980666596807	0.0225012649893587	O15400,Q86Y82,Q12846,O43752,Q9P2W9,Q13190,O95721	Functions	Panther Protein class	panther_protein_class	626,459,452,206,81,365,122	626,206,122,452,365,459,81,678	0.5920441322650274,1.4286699849010147,1.9963496087227715,0.8141544886580385,0.9571562106244959,0.8141544886580385,2.436398337597714,0.5667757956444454	3367
Lysosomes	6	13	2.2791400855716364	0.0226587393104755	Q8IY95,Q8WTV0,O60749,Q9UNH7,P02786,O14964	Localization	Protein Atlas Subcellular	protein_atlas_subcellular_location_all	428,9,416,643,529,434	434,626,416,1627,529,1214,2235,1535,1709,428,9,1344,643	0.8382620619356581,0.5920441322650274,0.862258844628111,-0.050263952997597124,0.6919219483408452,0.17253621044918402,-0.34234834725948426,0.006307474011367515,-0.07877373131780484,0.862258844628111,4.324586732934785,0.11769676093724667,0.5920441322650274	3367
Glycosyltransferase	7	31	2.2703837635738155	0.0231843087436898	Q9BT22,P43490,Q13126,O43505,Q10472,P04062,Q2TAA5	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	292,257,41,87,308,56,222	709,87,2286,1572,1998,2169,56,1139,2494,1460,2762,1812,1041,1935,257,686,2356,1428,654,308,41,222,1285,1286,1235,908,410,292,1788,2157,1739	0.5158731784643796,2.3478963961729225,-0.3724389183184647,-0.02190402285820215,-0.2236212584096826,-0.31242291199836886,2.888427682882454,0.22681944749468783,-0.49448594888254555,0.03437193328851483,-0.7148241860051961,-0.1362485904097433,0.2805565672472788,-0.19434031752410985,1.2095131214680288,0.5413858311413456,-0.40269627647094874,0.062290731757696595,0.5667757956444454,1.0503522207387042,3.227809668601115,1.3639014130956277,0.1451866537146581,0.1451866537146581,0.17253621044918402,0.38643153062342506,0.8861457519054411,1.1191654406700127,-0.1074347923116181,-0.2826609847711293,-0.07877373131780484	3367
Regulation of blood pressure	6	17	2.2678089912906505	0.0233408511568375	Q9UIQ6,P42892,P42785,P09601,Q9HB40,Q9NZ08	Processes and pathways	GO Biological process	msigdb_gobp	228,35,18,21,58,156	3328,2922,1213,21,3162,927,18,35,512,1328,234,1227,2785,58,156,228,844	-2.131961245664126,-0.8777714879158465,0.17253621044918402,3.613683844728898,-1.2539690378581203,0.3601597156898264,3.8282095648532786,3.2722740469256966,0.7165975954483155,0.11769676093724667,1.2983027806935246,0.17253621044918402,-0.7148241860051961,2.840232108692598,1.7406977485275759,1.3421283755465698,0.4385882859122563	3367
Hormone metabolic process	8	26	2.266413205952767	0.0234260957864758	P42892,O75844,P16435,Q9UBM7,Q9HB40,O95470,P30536,Q14849	Processes and pathways	GO Biological process	msigdb_gobp	35,68,293,185,58,123,124,31	1927,68,123,1213,1930,2763,293,124,35,3279,1586,2660,3114,31,1277,351,582,1017,1237,2030,2603,3152,58,185,2967,2281	-0.19434031752410985,2.6926945390869426,1.9771403969263128,0.17253621044918402,-0.19434031752410985,-0.7148241860051961,1.0963292676298746,1.9771403969263128,3.2722740469256966,-1.6192482414532234,-0.02190402285820215,-0.6193116841420223,-1.1488380282478365,3.3454673481684774,0.1451866537146581,0.9806125526787869,0.6422200972561323,0.30722341578558393,0.17253621044918402,-0.2236212584096826,-0.5565443734227432,-1.2187064928309388,2.840232108692598,1.5137692083085525,-0.9109430815275097,-0.34234834725948426	3367
Neuronal loss in central nervous system	6	11	2.2560803492753205	0.0240655995567735	O15118,P07602,Q9NZJ7,P35637,Q9BTW9,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	96,113,641,332,639,56	96,1455,1753,56,113,1635,332,999,662,639,641	2.2759315653971224,0.03437193328851483,-0.1074347923116181,2.888427682882454,2.110076974296961,-0.050263952997597124,1.0039634351651625,0.30722341578558393,0.5667757956444454,0.5920441322650274,0.5920441322650274	3367
Apical plasma membrane	20	39	2.252806861924388	0.024271329354961	P15311,P04083,Q15043,P08183,P35241,O75955,O75970,P41440,P54709,Q86UE4,P21281,P53985,Q9Y4G8,Q16625,Q14254,P26038,Q99808,P30825,Q9P289,P08238	Localization	GO Cellular component	msigdb_gocc	630,753,263,146,531,528,784,167,792,171,548,553,59,188,691,451,470,85,642,754	1990,961,1924,528,784,753,1213,146,1091,1265,754,1215,2923,630,1042,927,548,451,85,531,970,2291,2498,167,553,792,2236,2502,1226,2361,691,263,822,188,171,470,2159,642,59	-0.2236212584096826,0.3337574021162552,-0.19434031752410985,0.6919219483408452,0.46447550012638145,0.490236763907363,0.17253621044918402,1.7808852976154201,0.25375565145434276,0.1451866537146581,0.490236763907363,0.17253621044918402,-0.8777714879158465,0.5920441322650274,0.2805565672472788,0.3601597156898264,0.6671297810793578,0.8141544886580385,2.3834885282361222,0.6919219483408452,0.3337574021162552,-0.3724389183184647,-0.49448594888254555,1.6181799067894833,0.6671297810793578,0.46447550012638145,-0.34234834725948426,-0.49448594888254555,0.17253621044918402,-0.40269627647094874,0.5413858311413456,1.187074181061587,0.4385882859122563,1.4926272539284748,1.5974688426783576,0.7899351985641869,-0.2826609847711293,0.5920441322650274,2.840232108692598	3367
Coated vesicle	21	83	2.2513445204623728	0.0243637250809383	P24390,O95070,Q14108,P49755,P04439,Q5VW38,P02786,P05067,P42892,O43752,Q9Y3B3,Q9Y282,Q8N511,Q9Y5X1,O00203,P10321,P51572,Q13190,Q08379,P49257,P20645	Localization	GO Cellular component	msigdb_gocc	2,377,6,511,389,23,529,160,35,206,219,84,90,492,473,229,238,365,497,496,251	473,1869,892,3327,1315,1318,206,3221,894,2825,1807,1809,1360,377,964,1754,2055,598,529,389,160,1214,2617,229,1999,1757,816,1758,251,2,1324,35,1180,496,511,1145,2976,238,2835,2406,2501,1269,2708,3081,2836,2130,2351,2133,1535,1707,497,975,2456,365,2013,6,1538,2247,1951,2017,23,1107,90,828,1608,640,1557,1858,1614,2207,1248,841,567,2641,2725,2965,1566,2043,84,219,492,1082,1684	0.7656032541864601,-0.16521660034488708,0.38643153062342506,-2.131961245664126,0.11769676093724667,0.11769676093724667,1.4286699849010147,-1.4336660463047972,0.38643153062342506,-0.7794292005641262,-0.1362485904097433,-0.1362485904097433,0.09006522764362623,0.9335935466195544,0.3337574021162552,-0.1074347923116181,-0.2530609609086133,0.6171918880980484,0.6919219483408452,0.9099236880488443,1.7001874873242686,0.17253621044918402,-0.5878385067985065,1.3202624041063196,-0.2236212584096826,-0.1074347923116181,0.4385882859122563,-0.1074347923116181,1.231854696356683,4.631429349052777,0.11769676093724667,3.2722740469256966,0.19974671831673846,0.7411577066416265,0.7165975954483155,0.22681944749468783,-0.9443136123937819,1.2762487791777117,-0.7794292005641262,-0.4331220969912666,-0.49448594888254555,0.1451866537146581,-0.6509657620201212,-1.0798288811157457,-0.7794292005641262,-0.2826609847711293,-0.40269627647094874,-0.2826609847711293,0.006307474011367515,-0.07877373131780484,0.7411577066416265,0.3337574021162552,-0.4637180795900233,0.9571562106244959,-0.2236212584096826,4.383005400114565,0.006307474011367515,-0.34234834725948426,-0.19434031752410985,-0.2236212584096826,3.558475521936399,0.25375565145434276,2.33000339930892,0.4385882859122563,-0.02190402285820215,0.5920441322650274,0.006307474011367515,-0.1362485904097433,-0.02190402285820215,-0.31242291199836886,0.17253621044918402,0.4385882859122563,0.6671297810793578,-0.5878385067985065,-0.6509657620201212,-0.9109430815275097,0.006307474011367515,-0.2236212584096826,2.401188502744234,1.3855822269020739,0.7656032541864601,0.2805565672472788,-0.050263952997597124	3367
Joint contracture of the hand	12	57	2.24939152898767	0.024487597076124	Q99741,P42892,O75844,Q8WVQ1,P16435,Q9UP83,Q8IZA0,Q71SY5,Q15392,Q9NR77,O43933,Q9UJX6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	327,35,68,103,293,375,172,78,79,148,92,254	781,1170,711,3190,92,1136,2332,68,1173,1522,853,1462,293,898,3111,2702,1419,2581,2176,1820,35,1326,2661,1146,1707,3260,797,1476,728,2302,2188,79,2254,3218,1845,78,537,172,1851,103,2680,2470,1157,2960,1300,327,432,837,1792,3027,148,254,2042,375,1168,2433,1035	0.46447550012638145,0.19974671831673846,0.5158731784643796,-1.3251632411413339,2.294021415669942,0.22681944749468783,-0.40269627647094874,2.6926945390869426,0.19974671831673846,0.006307474011367515,0.41257400595833643,0.03437193328851483,1.0963292676298746,0.38643153062342506,-1.1488380282478365,-0.6509657620201212,0.062290731757696595,-0.5565443734227432,-0.31242291199836886,-0.1362485904097433,3.2722740469256966,0.11769676093724667,-0.6193116841420223,0.22681944749468783,-0.07877373131780484,-1.5442869665963095,0.46447550012638145,0.03437193328851483,0.5158731784643796,-0.3724389183184647,-0.31242291199836886,2.471357400586925,-0.34234834725948426,-1.3972667312364715,-0.1362485904097433,2.4887438961354635,0.6919219483408452,1.5974688426783576,-0.1362485904097433,2.2029028392455228,-0.6193116841420223,-0.4637180795900233,0.22681944749468783,-0.9109430815275097,0.1451866537146581,1.0272097103903832,0.862258844628111,0.4385882859122563,-0.1074347923116181,-0.977885243317303,1.7808852976154201,1.231854696356683,-0.2236212584096826,0.9571562106244959,0.22681944749468783,-0.4331220969912666,0.30722341578558393	3367
Peptide binding	20	71	2.24228536823542	0.0249429347961525	Q99735,P24390,Q8WTV0,P04439,Q8TEX9,Q9BYT8,Q9NZ08,P42892,P55899,O00264,Q9H7Z7,Q15392,Q92973,P52292,P55786,P30533,Q14978,Q9UIQ6,P10321,O14773	Functions	GO Molecular function	msigdb_gomf	260,2,9,389,538,151,156,35,422,304,65,79,469,466,93,225,482,228,229,108	594,304,527,2327,108,963,3274,2220,2394,2761,598,389,754,1214,2617,229,1930,2925,3076,2,2538,969,3240,1636,225,1143,2767,35,3185,2127,761,1702,466,2657,1703,93,422,1704,2237,1765,2133,2931,3046,2839,1537,2741,1769,2013,2016,482,79,2308,538,9,469,2555,1608,1197,260,2854,151,1400,65,1405,156,992,2607,228,3136,2485,2918	0.6171918880980484,1.0503522207387042,0.6919219483408452,-0.40269627647094874,2.1474158808446684,0.3337574021162552,-1.6192482414532234,-0.34234834725948426,-0.4331220969912666,-0.7148241860051961,0.6171918880980484,0.9099236880488443,0.490236763907363,0.17253621044918402,-0.5878385067985065,1.3202624041063196,-0.19434031752410985,-0.8777714879158465,-1.0798288811157457,4.631429349052777,-0.525427454868466,0.3337574021162552,-1.4703006768417601,-0.050263952997597124,1.3421283755465698,0.22681944749468783,-0.7148241860051961,3.2722740469256966,-1.2894537744189682,-0.2826609847711293,0.490236763907363,-0.07877373131780484,0.7899351985641869,-0.6193116841420223,-0.07877373131780484,2.294021415669942,0.862258844628111,-0.07877373131780484,-0.34234834725948426,-0.1074347923116181,-0.2826609847711293,-0.8777714879158465,-1.011660171259644,-0.7794292005641262,0.006307474011367515,-0.682802624960496,-0.1074347923116181,-0.2236212584096826,-0.2236212584096826,0.7656032541864601,2.471357400586925,-0.3724389183184647,0.6919219483408452,4.324586732934785,0.7899351985641869,-0.525427454868466,-0.02190402285820215,0.19974671831673846,1.2095131214680288,-0.7794292005641262,1.7608315718187155,0.09006522764362623,2.742374563169135,0.09006522764362623,1.7406977485275759,0.3337574021162552,-0.5565443734227432,1.3421283755465698,-1.1836636419604167,-0.4637180795900233,-0.8447967022235733	3367
Organophosphate ester transmembrane transporter activity	8	11	2.2340845729639427	0.0254775088743117	Q6NUK1,P41440,Q9HC21,Q9BSK2,Q99808,P12236,Q9H2D1,Q8TB61	Functions	GO Molecular function	msigdb_gomf	660,167,107,314,470,361,86,125	645,995,1040,361,167,660,125,470,314,86,107	0.5667757956444454,0.30722341578558393,0.2805565672472788,0.9571562106244959,1.6181799067894833,0.5667757956444454,1.9578570786990497,0.7899351985641869,1.0503522207387042,2.3657246319376566,2.165980585241542	3367
Nucleotide transmembrane transporter activity	8	11	2.2340845729639427	0.0254775088743117	Q6NUK1,P41440,Q9HC21,Q9BSK2,Q99808,P12236,Q9H2D1,Q8TB61	Functions	GO Molecular function	msigdb_gomf	660,167,107,314,470,361,86,125	645,995,1040,361,167,660,125,470,314,86,107	0.5667757956444454,0.30722341578558393,0.2805565672472788,0.9571562106244959,1.6181799067894833,0.5667757956444454,1.9578570786990497,0.7899351985641869,1.0503522207387042,2.3657246319376566,2.165980585241542	3367
Nucleotide transport	8	11	2.2340845729639427	0.0254775088743117	Q6NUK1,P41440,Q9HC21,Q9BSK2,Q99808,P12236,Q9H2D1,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	660,167,107,314,470,361,86,125	645,995,1040,361,167,660,125,470,314,86,107	0.5667757956444454,0.30722341578558393,0.2805565672472788,0.9571562106244959,1.6181799067894833,0.5667757956444454,1.9578570786990497,0.7899351985641869,1.0503522207387042,2.3657246319376566,2.165980585241542	3367
Target SNARE coiled-coil homology domain [IPR000727]	6	7	2.2265821192652773	0.0259752150811447	O15400,Q86Y82,Q12846,O43752,Q13190,O95721	Sequence	InterPro Domain	interpro_domain	626,459,452,206,365,122	626,206,122,452,365,459,678	0.5920441322650274,1.4286699849010147,1.9963496087227715,0.8141544886580385,0.9571562106244959,0.8141544886580385,0.5667757956444454	3367
Transport of small molecules	41	138	2.22124912453598	0.0263340926149646	Q15043,Q8WTV0,Q93050,P30519,P08183,P09601,Q99623,Q8IYU8,P27105,P45880,P35613,P49721,Q9Y277,P21796,Q9HD20,Q92667,Q9BUN8,Q9UJZ1,Q15904,P28070,Q658P3,P16615,P61289,P51798,Q70HW3,Q9UI12,Q9C0H2,P30825,P20618,O95202,O75027,Q9Y487,Q9UBX3,Q9UL46,O15118,O00231,Q9BU23,P12236,Q9UEY8,P28072,Q8TB61	Processes and pathways	Reactome Pathways	msigdb_reactome	263,9,265,16,146,21,282,150,157,29,286,36,166,34,165,298,301,317,182,306,189,305,321,71,77,341,80,85,331,330,211,358,91,356,96,345,373,361,119,252,125	345,2611,1921,2388,96,388,211,2647,3160,1359,1808,1809,330,2055,529,1213,995,1755,599,146,1091,1214,21,897,1215,1040,361,1882,305,788,927,1174,331,548,2897,1141,34,3058,1817,3124,3251,157,3225,306,252,1933,855,16,3125,85,2707,1046,858,2003,286,2900,1637,970,3228,2498,2620,29,1890,3060,36,724,71,1269,553,792,2236,2295,3013,533,534,321,2502,2008,794,2590,2870,3310,2133,1184,1534,1535,1429,655,1829,1647,764,1770,2981,2669,1005,1950,263,1433,182,189,2192,77,1779,150,772,1604,125,9,1196,298,265,1608,521,522,1666,2034,282,470,948,373,301,80,622,2785,1972,165,1509,91,119,2483,341,317,356,2109,745,166,358,1133	0.9806125526787869,-0.5878385067985065,-0.19434031752410985,-0.4331220969912666,2.2759315653971224,0.9099236880488443,1.3855822269020739,-0.6193116841420223,-1.2539690378581203,0.09006522764362623,-0.1362485904097433,-0.1362485904097433,1.0039634351651625,-0.2530609609086133,0.6919219483408452,0.17253621044918402,0.30722341578558393,-0.1074347923116181,0.6171918880980484,1.7808852976154201,0.25375565145434276,0.17253621044918402,3.613683844728898,0.38643153062342506,0.17253621044918402,0.2805565672472788,0.9571562106244959,-0.16521660034488708,1.0503522207387042,0.46447550012638145,0.3601597156898264,0.19974671831673846,1.0039634351651625,0.6671297810793578,-0.8447967022235733,0.22681944749468783,3.2722740469256966,-1.0456406280505959,-0.1362485904097433,-1.1836636419604167,-1.507173381664675,1.7204832487252557,-1.4336660463047972,1.0503522207387042,1.231854696356683,-0.19434031752410985,0.41257400595833643,3.9318663108151224,-1.1836636419604167,2.3834885282361222,-0.6509657620201212,0.2805565672472788,0.41257400595833643,-0.2236212584096826,1.1191654406700127,-0.8447967022235733,-0.050263952997597124,0.3337574021162552,-1.4336660463047972,-0.49448594888254555,-0.5878385067985065,3.403217513344748,-0.16521660034488708,-1.0456406280505959,3.2722740469256966,0.5158731784643796,2.6256544201008225,0.1451866537146581,0.6671297810793578,0.46447550012638145,-0.34234834725948426,-0.3724389183184647,-0.977885243317303,0.6919219483408452,0.6919219483408452,1.0272097103903832,-0.49448594888254555,-0.2236212584096826,0.46447550012638145,-0.5565443734227432,-0.8120166279085533,-1.889636471997411,-0.2826609847711293,0.19974671831673846,0.006307474011367515,0.006307474011367515,0.062290731757696595,0.5667757956444454,-0.1362485904097433,-0.050263952997597124,0.490236763907363,-0.1074347923116181,-0.9443136123937819,-0.6193116841420223,0.30722341578558393,-0.19434031752410985,1.187074181061587,0.062290731757696595,1.5137692083085525,1.4926272539284748,-0.31242291199836886,2.5060688955133497,-0.1074347923116181,1.7608315718187155,0.490236763907363,-0.02190402285820215,1.9578570786990497,4.324586732934785,0.19974671831673846,1.07339179882247,1.187074181061587,-0.02190402285820215,0.7165975954483155,0.7165975954483155,-0.050263952997597124,-0.2236212584096826,1.1419011221151822,0.7899351985641869,0.3601597156898264,0.9571562106244959,1.07339179882247,2.4539090139419626,0.6171918880980484,-0.7148241860051961,-0.19434031752410985,1.6388066898289295,0.03437193328851483,2.312045215706412,2.0535377021037875,-0.4637180795900233,1.0039634351651625,1.0503522207387042,0.9806125526787869,-0.2530609609086133,0.5158731784643796,1.6388066898289295,0.9806125526787869,0.25375565145434276	3367
Protein transmembrane transport	7	24	2.2199295987764174	0.0264235469304949	Q9NS69,Q99595,O14925,Q15629,O60830,O43933,Q99442	Processes and pathways	GO Biological process	msigdb_gobp	0,37,262,11,47,92,383	262,376,92,47,713,2761,716,1361,1999,1462,574,511,3356,3128,1704,2237,11,2018,1601,383,37,1307,0,743	1.187074181061587,0.9335935466195544,2.294021415669942,3.107165693020846,0.5158731784643796,-0.7148241860051961,0.5158731784643796,0.09006522764362623,-0.2236212584096826,0.03437193328851483,0.6422200972561323,0.7165975954483155,-3.3665191515672723,-1.1836636419604167,-0.07877373131780484,-0.34234834725948426,4.156903668614397,-0.2236212584096826,-0.02190402285820215,0.9335935466195544,3.2722740469256966,0.1451866537146581,4.803828948758111,0.5158731784643796	3367
serine protease	6	18	2.215775878835102	0.0267068552186617	P67812,P10619,Q9H3G5,P42785,Q16740,Q9HB40	Functions	Panther Protein class	panther_protein_class	98,40,12,18,89,58	108,40,3072,2947,2899,1094,18,2542,98,89,395,439,2877,442,3347,12,58,3237	2.1474158808446684,3.227809668601115,-1.0798288811157457,-0.9109430815275097,-0.8447967022235733,0.25375565145434276,3.8282095648532786,-0.525427454868466,2.2759315653971224,2.33000339930892,0.9099236880488443,0.8382620619356581,-0.8120166279085533,0.8382620619356581,-2.559722816212025,4.144687074033624,2.840232108692598,-1.4336660463047972	3367
Dicarboxylic acid transport	6	15	2.2123731627350787	0.0269408916476612	Q15041,P41440,P80404,O75746,Q9H2D1,Q9UBX3	Processes and pathways	GO Biological process	msigdb_gobp	295,167,234,508,86,91	1517,508,1873,1877,167,2236,234,1223,295,2188,1433,86,1972,91,677	0.006307474011367515,0.7165975954483155,-0.16521660034488708,-0.16521660034488708,1.6181799067894833,-0.34234834725948426,1.2983027806935246,0.17253621044918402,1.0963292676298746,-0.31242291199836886,0.062290731757696595,2.3657246319376566,-0.19434031752410985,2.312045215706412,0.5667757956444454	3367
Toll like receptor signaling pathway	8	19	2.207810657733052	0.0272574748168676	Q5KU26,O00203,P41440,Q9NQC3,P09429,Q9H1C4,Q9NPR9,P51617	Processes and pathways	GO Biological process	msigdb_gobp	193,473,167,106,417,174,52,307	473,1922,3003,3190,528,1574,417,1999,167,307,1097,2455,691,193,1282,174,52,106,1512	0.7656032541864601,-0.19434031752410985,-0.977885243317303,-1.3251632411413339,0.6919219483408452,-0.02190402285820215,0.862258844628111,-0.2236212584096826,1.6181799067894833,1.0503522207387042,0.25375565145434276,-0.4637180795900233,0.5413858311413456,1.471397176367932,0.1451866537146581,1.5766728741783365,2.9676974850627826,2.1844760833621826,0.03437193328851483	3367
Abnormal circulating cholesterol concentration	14	33	2.194491955464038	0.0282000616457744	Q14739,P50402,Q9UJS0,Q15392,Q15800,Q15125,Q9NVI7,P07602,P34913,Q15904,Q13045,Q9NZJ7,Q9UBM7,Q8N511	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,420,677,79,110,177,503,113,181,182,216,641,185,90	2331,1522,1139,113,181,2125,3228,999,2804,420,2977,1146,2008,1707,654,216,1476,289,177,79,2842,110,182,1388,2510,90,1493,1116,808,503,641,185,677	-0.40269627647094874,0.006307474011367515,0.22681944749468783,2.110076974296961,1.5137692083085525,-0.2826609847711293,-1.4336660463047972,0.30722341578558393,-0.7470323872777213,0.862258844628111,-0.9443136123937819,0.22681944749468783,-0.2236212584096826,-0.07877373131780484,0.5667757956444454,1.3855822269020739,0.03437193328851483,1.1191654406700127,1.5348236972160396,2.471357400586925,-0.7794292005641262,2.1287815015903986,1.5137692083085525,0.09006522764362623,-0.49448594888254555,2.33000339930892,0.03437193328851483,0.25375565145434276,0.46447550012638145,0.7411577066416265,0.5920441322650274,1.5137692083085525,0.5667757956444454	3367
Regulation of system process	10	59	2.1930031556247847	0.0283071517341964	P05067,P42892,O75844,P78417,P80404,Q9UQB8,P10253,Q99996,P04062,P16615	Processes and pathways	GO Biological process	msigdb_gobp	160,35,68,72,234,14,269,184,56,305	961,1357,2223,508,68,1359,2761,2616,1522,56,1212,1213,160,3006,1810,1460,269,2061,1632,3122,3288,305,927,3111,969,3125,2443,35,512,1891,1328,2501,2710,1098,72,234,3114,1273,2839,1225,606,3101,1770,2981,2014,1103,1596,866,2411,322,1112,1720,184,2202,1733,2785,1350,14,844	0.3337574021162552,0.09006522764362623,-0.34234834725948426,0.7165975954483155,2.6926945390869426,0.09006522764362623,-0.7148241860051961,-0.5878385067985065,0.006307474011367515,2.888427682882454,0.17253621044918402,0.17253621044918402,1.7001874873242686,-0.977885243317303,-0.1362485904097433,0.03437193328851483,1.164537106940616,-0.2530609609086133,-0.050263952997597124,-1.1836636419604167,-1.695207928870715,1.0503522207387042,0.3601597156898264,-1.1488380282478365,0.3337574021162552,-1.1836636419604167,-0.4637180795900233,3.2722740469256966,0.7165975954483155,-0.16521660034488708,0.11769676093724667,-0.49448594888254555,-0.6509657620201212,0.25375565145434276,2.59178502036956,1.2983027806935246,-1.1488380282478365,0.1451866537146581,-0.7794292005641262,0.17253621044918402,0.6171918880980484,-1.1142272342228774,-0.1074347923116181,-0.9443136123937819,-0.2236212584096826,0.25375565145434276,-0.02190402285820215,0.41257400595833643,-0.4331220969912666,1.0272097103903832,0.25375565145434276,-0.07877373131780484,1.5137692083085525,-0.31242291199836886,-0.07877373131780484,-0.7148241860051961,0.11769676093724667,4.083110142233152,0.4385882859122563	3367
Regulation of cellular ph	7	19	2.185196703211525	0.0288744271506096	P50897,Q93050,P06576,Q9UI12,Q15904,O75503,Q8N511	Processes and pathways	GO Biological process	msigdb_gobp	38,265,250,341,182,57,90	57,814,250,3263,2704,2581,38,2235,2502,1536,182,90,803,265,828,1680,341,358,3137	2.8563508480242543,0.4385882859122563,1.231854696356683,-1.5816442855181783,-0.6509657620201212,-0.5565443734227432,3.2574988008466623,-0.34234834725948426,-0.49448594888254555,0.006307474011367515,1.5137692083085525,2.33000339930892,0.46447550012638145,1.187074181061587,0.4385882859122563,-0.050263952997597124,1.0039634351651625,0.9806125526787869,-1.1836636419604167	3367
Regulation of ph	7	19	2.185196703211525	0.0288744271506096	P50897,Q93050,P06576,Q9UI12,Q15904,O75503,Q8N511	Processes and pathways	GO Biological process	msigdb_gobp	38,265,250,341,182,57,90	57,814,250,3263,2704,2581,38,2235,2502,1536,182,90,803,265,828,1680,341,358,3137	2.8563508480242543,0.4385882859122563,1.231854696356683,-1.5816442855181783,-0.6509657620201212,-0.5565443734227432,3.2574988008466623,-0.34234834725948426,-0.49448594888254555,0.006307474011367515,1.5137692083085525,2.33000339930892,0.46447550012638145,1.187074181061587,0.4385882859122563,-0.050263952997597124,1.0039634351651625,0.9806125526787869,-1.1836636419604167	3367
ATP synthase	8	19	2.1849301467392266	0.0288939687148697	P24539,Q93050,Q9UI12,O75964,P56385,Q15904,Q9Y487,P06576	Functions	Panther Protein class	panther_protein_class	378,265,341,17,214,182,358,250	851,17,250,548,2897,378,1580,759,2498,2928,2296,214,2502,182,427,265,947,341,358	0.41257400595833643,3.867353512797234,1.231854696356683,0.6671297810793578,-0.8447967022235733,0.9335935466195544,-0.02190402285820215,0.490236763907363,-0.49448594888254555,-0.8777714879158465,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,1.5137692083085525,0.862258844628111,1.187074181061587,0.3601597156898264,1.0039634351651625,0.9806125526787869	3367
Abnormal leukocyte physiology	29	66	2.16974558451	0.0300261246965967	Q96DF8,P40763,Q14108,Q9UJS0,P09601,P02786,P13051,P19447,P21964,P48506,Q96HA7,O00754,Q9NZC9,Q15904,P04062,P28070,Q96AX1,Q13043,Q92766,P26038,Q9H0U3,O00203,Q9UJW0,P04637,P42345,P14174,Q6PGP7,Q13546,Q15833	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	130,632,6,677,21,529,649,650,285,287,831,543,447,182,56,306,828,690,733,451,622,473,104,479,601,237,770,764,380	473,543,2051,2335,1574,1998,1522,529,56,479,21,2762,2652,3121,649,237,967,898,2399,650,2925,3111,285,451,2400,306,2899,632,601,287,1938,1530,2708,1049,2709,1050,1224,690,764,2183,6,2460,380,182,770,871,3065,733,2552,1969,828,130,831,2316,2423,622,1562,990,447,677,104,1745,2789,1081,1988,2919	0.7656032541864601,0.6671297810793578,-0.2530609609086133,-0.40269627647094874,-0.02190402285820215,-0.2236212584096826,0.006307474011367515,0.6919219483408452,2.888427682882454,0.7656032541864601,3.613683844728898,-0.7148241860051961,-0.6193116841420223,-1.1836636419604167,0.5667757956444454,1.2762487791777117,0.3337574021162552,0.38643153062342506,-0.4331220969912666,0.5667757956444454,-0.8777714879158465,-1.1488380282478365,1.1191654406700127,0.8141544886580385,-0.4331220969912666,1.0503522207387042,-0.8447967022235733,0.5920441322650274,0.6171918880980484,1.1191654406700127,-0.19434031752410985,0.006307474011367515,-0.6509657620201212,0.2805565672472788,-0.6509657620201212,0.2805565672472788,0.17253621044918402,0.5413858311413456,0.490236763907363,-0.31242291199836886,4.383005400114565,-0.4637180795900233,0.9335935466195544,1.5137692083085525,0.490236763907363,0.41257400595833643,-1.0456406280505959,0.5158731784643796,-0.525427454868466,-0.19434031752410985,0.4385882859122563,1.9384991366690936,0.4385882859122563,-0.3724389183184647,-0.4331220969912666,0.6171918880980484,0.006307474011367515,0.3337574021162552,0.8382620619356581,0.5667757956444454,2.2029028392455228,-0.07877373131780484,-0.7148241860051961,0.2805565672472788,-0.19434031752410985,-0.8447967022235733	3367
Abnormal tissue metabolite concentration	9	15	2.165903048579884	0.0303185963105607	P06280,P06865,Q9Y276,P07602,Q9NZJ7,P56589,Q658P3,O43933,P17900	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	255,347,342,113,641,533,189,92,221	1454,92,713,255,347,113,2649,1634,221,1586,533,189,2845,641,342	0.03437193328851483,2.294021415669942,0.5158731784643796,1.2095131214680288,0.9806125526787869,2.110076974296961,-0.6193116841420223,-0.050263952997597124,1.3639014130956277,-0.02190402285820215,0.6919219483408452,1.4926272539284748,-0.7794292005641262,0.5920441322650274,1.0039634351651625	3367
Glycerolipid metabolic process	15	65	2.16266669211683	0.0305668246839136	Q9H490,P35790,Q9BZF1,O15228,Q92604,Q8WTV0,Q96N66,Q8NCC3,Q6IAN0,Q9UJZ1,Q99623,Q8N2K0,Q9NPH0,Q53H12,O95674	Processes and pathways	GO Biological process	msigdb_gobp	261,256,400,474,398,9,137,10,517,317,282,442,88,440,436	3158,892,2858,474,2892,1572,1264,436,3287,2120,2439,818,2582,1759,2175,256,1819,1525,1526,1821,1181,1328,1707,3114,655,1379,2014,1952,440,517,1961,585,1115,442,518,10,1342,872,9,2551,1392,398,2312,1969,1440,1609,137,805,667,2719,1158,282,1070,987,1732,913,400,1162,261,88,1309,1204,742,317,1079	-1.2539690378581203,0.38643153062342506,-0.8120166279085533,0.7656032541864601,-0.8447967022235733,-0.02190402285820215,0.1451866537146581,0.8382620619356581,-1.695207928870715,-0.2826609847711293,-0.4637180795900233,0.4385882859122563,-0.5565443734227432,-0.1074347923116181,-0.31242291199836886,1.2095131214680288,-0.1362485904097433,0.006307474011367515,0.006307474011367515,-0.1362485904097433,0.19974671831673846,0.11769676093724667,-0.07877373131780484,-1.1488380282478365,0.5667757956444454,0.09006522764362623,-0.2236212584096826,-0.19434031752410985,0.8382620619356581,0.7165975954483155,-0.19434031752410985,0.6422200972561323,0.25375565145434276,0.8382620619356581,0.7165975954483155,4.301006972369739,0.11769676093724667,0.41257400595833643,4.324586732934785,-0.525427454868466,0.09006522764362623,0.9099236880488443,-0.3724389183184647,-0.19434031752410985,0.062290731757696595,-0.02190402285820215,1.8603105982788577,0.46447550012638145,0.5667757956444454,-0.6509657620201212,0.22681944749468783,1.1419011221151822,0.2805565672472788,0.3337574021162552,-0.07877373131780484,0.38643153062342506,0.9099236880488443,0.22681944749468783,1.2095131214680288,2.3478963961729225,0.1451866537146581,0.19974671831673846,0.5158731784643796,1.0503522207387042,0.2805565672472788	3367
Carbohydrate derivative transport	9	14	2.1610901707650108	0.0306883747050124	Q6NUK1,P41440,Q8WTV0,Q9HC21,Q99808,P07602,Q9NZJ7,P12236,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	660,167,9,107,470,113,641,361,125	3092,645,995,113,1040,361,167,2008,660,125,9,470,107,641	-1.1142272342228774,0.5667757956444454,0.30722341578558393,2.110076974296961,0.2805565672472788,0.9571562106244959,1.6181799067894833,-0.2236212584096826,0.5667757956444454,1.9578570786990497,4.324586732934785,0.7899351985641869,2.165980585241542,0.5920441322650274	3367
Proton transmembrane transporter activity	10	31	2.157196943381185	0.0309903225380865	Q9Y487,P13073,Q93050,Q9UI12,Q9UDW1,O75964,P56385,O95202,Q13423,P06576	Functions	GO Molecular function	msigdb_gomf	358,73,265,341,112,17,214,330,278,250	851,17,330,718,995,250,1756,2060,1040,73,819,548,2897,378,1580,3193,759,970,2498,1889,2928,2296,214,2502,1186,278,265,1972,112,341,358	0.41257400595833643,3.867353512797234,1.0039634351651625,0.5158731784643796,0.30722341578558393,1.231854696356683,-0.1074347923116181,-0.2530609609086133,0.2805565672472788,2.5747617035953736,0.4385882859122563,0.6671297810793578,-0.8447967022235733,0.9335935466195544,-0.02190402285820215,-1.3251632411413339,0.490236763907363,0.3337574021162552,-0.49448594888254555,-0.16521660034488708,-0.8777714879158465,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,0.19974671831673846,1.1419011221151822,1.187074181061587,-0.19434031752410985,2.1287815015903986,1.0039634351651625,0.9806125526787869	3367
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen	10	31	2.14845473895233	0.0316776482793768	Q16850,P16435,Q6UW02,P30519,Q15800,Q6PK18,P09601,Q7LBC6,Q9BU89,Q9Y4C1	Functions	GO Molecular function	msigdb_gomf	131,293,200,16,110,612,21,613,384,593	1800,1083,3181,1994,2286,2490,2576,599,21,786,293,1581,16,1820,1331,1148,1829,938,110,131,868,1280,2365,612,200,613,384,1733,2275,2044,593	-0.1362485904097433,0.25375565145434276,-1.2894537744189682,-0.2236212584096826,-0.3724389183184647,-0.49448594888254555,-0.5565443734227432,0.6171918880980484,3.613683844728898,0.46447550012638145,1.0963292676298746,-0.02190402285820215,3.9318663108151224,-0.1362485904097433,0.11769676093724667,0.22681944749468783,-0.1362485904097433,0.3601597156898264,2.1287815015903986,1.9190660482263868,0.41257400595833643,0.1451866537146581,-0.40269627647094874,0.6171918880980484,1.450078310745009,0.6171918880980484,0.9335935466195544,-0.07877373131780484,-0.34234834725948426,-0.2236212584096826,0.6422200972561323	3367
Cristae formation	6	9	2.140828716264264	0.0322878533091719	Q5XKP0,Q9NX63,Q9BUR5,O95202,Q6UXV4,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	581,316,412,330,121,381	330,381,581,121,412,1310,316,1133,644	1.0039634351651625,0.9335935466195544,0.6422200972561323,2.0154852262905982,0.8861457519054411,0.1451866537146581,1.0503522207387042,0.25375565145434276,0.5920441322650274	3367
Inner mitochondrial membrane organization	11	19	2.129933096798207	0.0331771372262901	Q13505,Q6UXV4,Q5XKP0,O60313,Q9NX63,Q9Y512,Q9BUR5,O95202,Q53H12,Q9P0J0,Q16891	Processes and pathways	GO Biological process	msigdb_gobp	99,121,581,359,316,644,412,330,440,386,381	359,2331,2761,330,3143,99,381,440,581,121,1196,412,672,1310,316,386,1133,644,2755	0.9571562106244959,-0.40269627647094874,-0.7148241860051961,1.0039634351651625,-1.2187064928309388,2.2759315653971224,0.9335935466195544,0.8382620619356581,0.6422200972561323,2.0154852262905982,0.19974671831673846,0.8861457519054411,0.5667757956444454,0.1451866537146581,1.0503522207387042,0.9335935466195544,0.25375565145434276,0.5920441322650274,-0.682802624960496	3367
Calcium-binding protein	6	17	2.1277064444236404	0.0333614302716147	Q14257,P80303,Q9BRK5,Q02818,Q8IYU8,P43307	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	192,1,162,54,150,28	243,2538,3264,28,3082,1,54,192,1007,3311,1232,150,2418,2744,948,162,1033	1.254099665260839,-0.525427454868466,-1.5816442855181783,3.4175453651007617,-1.0798288811157457,4.739957488800412,2.9519476787527323,1.471397176367932,0.30722341578558393,-1.889636471997411,0.17253621044918402,1.7608315718187155,-0.4331220969912666,-0.682802624960496,0.3601597156898264,1.679809873082842,0.30722341578558393	3367
Loss of speech	7	20	2.1239753008352635	0.0336722089576941	O15118,Q13501,P50897,O00754,P07602,Q9NZJ7,P17900	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	96,657,38,543,113,641,221	543,96,1454,2759,1808,113,1634,221,38,1328,2178,3013,1330,2008,657,728,2250,1613,641,1983	0.6671297810793578,2.2759315653971224,0.03437193328851483,-0.7148241860051961,-0.1362485904097433,2.110076974296961,-0.050263952997597124,1.3639014130956277,3.2574988008466623,0.11769676093724667,-0.31242291199836886,-0.977885243317303,0.11769676093724667,-0.2236212584096826,0.5667757956444454,0.5158731784643796,-0.34234834725948426,-0.02190402285820215,0.5920441322650274,-0.19434031752410985	3367
Apical part of cell	24	51	2.1097453181248373	0.0348802987518597	P15311,P04083,Q15043,Q8NCM8,P08183,P35241,O75955,P05067,O75970,P41440,P54709,Q86UE4,P21281,P53985,Q15154,Q9Y4G8,Q16625,Q14254,Q16181,P26038,Q99808,P30825,Q9P289,P08238	Localization	GO Cellular component	msigdb_gocc	630,753,263,801,146,531,528,160,784,167,792,171,548,553,438,59,188,691,822,451,470,85,642,754	1990,961,1924,2219,528,784,753,1213,160,146,1091,1265,754,1215,2923,630,1042,927,548,2897,451,85,1818,531,970,2291,2498,167,553,792,2236,2449,2502,1828,1226,2361,1102,691,263,438,822,188,171,801,877,470,2159,642,3000,59,3137	-0.2236212584096826,0.3337574021162552,-0.19434031752410985,-0.34234834725948426,0.6919219483408452,0.46447550012638145,0.490236763907363,0.17253621044918402,1.7001874873242686,1.7808852976154201,0.25375565145434276,0.1451866537146581,0.490236763907363,0.17253621044918402,-0.8777714879158465,0.5920441322650274,0.2805565672472788,0.3601597156898264,0.6671297810793578,-0.8447967022235733,0.8141544886580385,2.3834885282361222,-0.1362485904097433,0.6919219483408452,0.3337574021162552,-0.3724389183184647,-0.49448594888254555,1.6181799067894833,0.6671297810793578,0.46447550012638145,-0.34234834725948426,-0.4637180795900233,-0.49448594888254555,-0.1362485904097433,0.17253621044918402,-0.40269627647094874,0.25375565145434276,0.5413858311413456,1.187074181061587,0.8382620619356581,0.4385882859122563,1.4926272539284748,1.5974688426783576,0.46447550012638145,0.41257400595833643,0.7899351985641869,-0.2826609847711293,0.5920441322650274,-0.9443136123937819,2.840232108692598,-1.1836636419604167	3367
Inorganic anion transmembrane transporter activity	6	14	2.1095479403412942	0.0348973125348233	Q9Y277,P21796,P51798,Q9C0H2,Q9UBX3,P45880	Functions	GO Molecular function	msigdb_gomf	166,34,71,80,91,29	2756,1454,3263,34,29,71,2236,1223,263,3206,80,91,166,3137	-0.7148241860051961,0.03437193328851483,-1.5816442855181783,3.2722740469256966,3.403217513344748,2.6256544201008225,-0.34234834725948426,0.17253621044918402,1.187074181061587,-1.3611000187999303,2.4539090139419626,2.312045215706412,1.6388066898289295,-1.1836636419604167	3367
Glycerophospholipid biosynthesis	11	31	2.109526693681893	0.0348991443996515	P35790,Q9BZF1,Q92604,Q96N66,Q8NCC3,Q8IV08,Q9NQZ5,Q9NPH0,Q53H12,O95674,Q8N2A8	Processes and pathways	Reactome Pathways	msigdb_reactome	256,400,398,137,10,441,117,88,440,436,259	2858,474,2489,436,2120,2226,256,1819,1465,1821,1528,2447,2625,440,585,441,259,1720,2957,10,1342,2551,398,137,2719,3117,1070,400,88,117,742	-0.8120166279085533,0.7656032541864601,-0.49448594888254555,0.8382620619356581,-0.2826609847711293,-0.34234834725948426,1.2095131214680288,-0.1362485904097433,0.03437193328851483,-0.1362485904097433,0.006307474011367515,-0.4637180795900233,-0.5878385067985065,0.8382620619356581,0.6422200972561323,0.8382620619356581,1.2095131214680288,-0.07877373131780484,-0.9109430815275097,4.301006972369739,0.11769676093724667,-0.525427454868466,0.9099236880488443,1.8603105982788577,-0.6509657620201212,-1.1488380282478365,0.2805565672472788,0.9099236880488443,2.3478963961729225,2.072455559506005,0.5158731784643796	3367
Absent septum pellucidum	11	37	2.1023213846531186	0.0355251325530932	Q6P1N0,O14974,Q96N66,O96028,Q71SY5,Q15392,Q2M1P5,O43505,Q2M389,O95202,Q8N3U4	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	258,231,137,236,78,79,246,87,310,330,353	231,711,87,2329,330,236,630,1821,2543,363,2236,1475,1895,2953,2409,1103,2073,79,246,310,258,1281,78,353,2466,1496,2556,137,1558,2816,564,1202,1129,1406,2384,2966,3250	1.2983027806935246,0.5158731784643796,2.3478963961729225,-0.40269627647094874,1.0039634351651625,1.2762487791777117,0.5920441322650274,-0.1362485904097433,-0.525427454868466,0.9571562106244959,-0.34234834725948426,0.03437193328851483,-0.16521660034488708,-0.9109430815275097,-0.4331220969912666,0.25375565145434276,-0.2530609609086133,2.471357400586925,1.254099665260839,1.0503522207387042,1.2095131214680288,0.1451866537146581,2.4887438961354635,0.9806125526787869,-0.4637180795900233,0.03437193328851483,-0.525427454868466,1.8603105982788577,0.006307474011367515,-0.7470323872777213,0.6671297810793578,0.19974671831673846,0.25375565145434276,0.09006522764362623,-0.40269627647094874,-0.9109430815275097,-1.4703006768417601	3367
Protein targeting	43	108	2.095490031832828	0.0361274536497588	Q9NS69,O43615,Q14108,O14925,Q9H9H4,P49840,Q15629,O00170,P56589,P07900,P43307,Q15005,P27105,P46379,P13473,Q5JRX3,Q99595,Q10713,Q15041,O60725,P46934,O60830,Q96RL7,Q53H12,O14964,Q7Z3B4,P31751,O14737,Q9UGP8,Q16543,O95831,O43933,P55786,O00203,P49458,P51572,Q9Y512,Q99442,P49257,Q9P0J0,P20645,P30536,O00560	Processes and pathways	GO Biological process	msigdb_gobp	0,376,6,262,401,512,11,268,533,648,28,406,157,30,161,658,37,655,295,170,419,47,700,440,434,584,574,205,743,729,716,92,93,473,603,238,644,383,496,386,251,124,625	2529,268,473,625,1515,205,262,434,376,1454,1992,92,170,47,713,2647,1629,2761,2860,2732,2056,716,1361,648,1929,1999,1757,161,2226,251,2703,157,2440,3140,124,3213,574,857,1934,2767,28,30,419,496,603,512,2235,238,93,533,3356,3128,2007,1704,2237,1705,1098,3016,1944,2739,655,1947,2456,1226,6,406,295,11,1189,729,2018,440,658,2599,1012,1658,584,942,1488,1601,1602,1193,700,3151,383,1123,1158,37,2102,2425,401,1307,0,884,386,2566,743,992,1680,2821,3157,918,2887,1624,1452,644,2755,891	-0.525427454868466,1.164537106940616,0.7656032541864601,0.5920441322650274,0.006307474011367515,1.4286699849010147,1.187074181061587,0.8382620619356581,0.9335935466195544,0.03437193328851483,-0.2236212584096826,2.294021415669942,1.5974688426783576,3.107165693020846,0.5158731784643796,-0.6193116841420223,-0.050263952997597124,-0.7148241860051961,-0.8120166279085533,-0.682802624960496,-0.2530609609086133,0.5158731784643796,0.09006522764362623,0.5667757956444454,-0.19434031752410985,-0.2236212584096826,-0.1074347923116181,1.679809873082842,-0.34234834725948426,1.231854696356683,-0.6509657620201212,1.7204832487252557,-0.4637180795900233,-1.2187064928309388,1.9771403969263128,-1.3972667312364715,0.6422200972561323,0.41257400595833643,-0.19434031752410985,-0.7148241860051961,3.4175453651007617,3.3454673481684774,0.862258844628111,0.7411577066416265,0.6171918880980484,0.7165975954483155,-0.34234834725948426,1.2762487791777117,2.294021415669942,0.6919219483408452,-3.3665191515672723,-1.1836636419604167,-0.2236212584096826,-0.07877373131780484,-0.34234834725948426,-0.07877373131780484,0.25375565145434276,-0.977885243317303,-0.19434031752410985,-0.682802624960496,0.5667757956444454,-0.19434031752410985,-0.4637180795900233,0.17253621044918402,4.383005400114565,0.8861457519054411,1.0963292676298746,4.156903668614397,0.19974671831673846,0.5158731784643796,-0.2236212584096826,0.8382620619356581,0.5667757956444454,-0.5565443734227432,0.30722341578558393,-0.050263952997597124,0.6422200972561323,0.3601597156898264,0.03437193328851483,-0.02190402285820215,-0.02190402285820215,0.19974671831673846,0.5413858311413456,-1.2187064928309388,0.9335935466195544,0.25375565145434276,0.22681944749468783,3.2722740469256966,-0.2530609609086133,-0.4331220969912666,0.9099236880488443,0.1451866537146581,4.803828948758111,0.41257400595833643,0.9335935466195544,-0.525427454868466,0.5158731784643796,0.3337574021162552,-0.050263952997597124,-0.7470323872777213,-1.2187064928309388,0.38643153062342506,-0.8120166279085533,-0.02190402285820215,0.062290731757696595,0.5920441322650274,-0.682802624960496,0.41257400595833643	3367
Calcium ion binding	17	83	2.095113616939132	0.0361608937496524	Q14257,P80303,Q9BRK5,O43852,O95202,Q8WVQ1,Q9Y680,Q9UM22,Q9H223,Q96AY3,P16615,Q02818,O75071,Q8IYU8,O60476,Q9Y4G8,P16455	Functions	GO Molecular function	msigdb_gomf	192,1,162,243,330,103,42,13,338,208,305,54,55,150,249,59,191	680,1354,1454,1085,243,249,55,2825,2490,508,1874,330,753,2121,2969,1697,1879,1810,2289,1320,817,3110,629,1418,1634,191,305,2439,1042,818,1321,1142,2538,1217,2766,3125,3264,2586,1465,1048,1822,3082,554,1643,1,54,973,3046,2839,1829,765,1103,1596,192,2772,1007,352,660,3148,1601,2811,2632,150,1342,1548,103,431,208,2744,445,3117,948,162,3256,338,1165,2725,1680,677,13,958,59,42	0.5413858311413456,0.09006522764362623,0.03437193328851483,0.25375565145434276,1.254099665260839,1.231854696356683,2.9202924545011304,-0.7794292005641262,-0.49448594888254555,0.7165975954483155,-0.16521660034488708,1.0039634351651625,0.490236763907363,-0.2826609847711293,-0.9443136123937819,-0.07877373131780484,-0.16521660034488708,-0.1362485904097433,-0.3724389183184647,0.11769676093724667,0.4385882859122563,-1.1488380282478365,0.5920441322650274,0.062290731757696595,-0.050263952997597124,1.471397176367932,1.0503522207387042,-0.4637180795900233,0.2805565672472788,0.4385882859122563,0.11769676093724667,0.22681944749468783,-0.525427454868466,0.17253621044918402,-0.7148241860051961,-1.1836636419604167,-1.5816442855181783,-0.5565443734227432,0.03437193328851483,0.2805565672472788,-0.1362485904097433,-1.0798288811157457,0.6671297810793578,-0.050263952997597124,4.739957488800412,2.9519476787527323,0.3337574021162552,-1.011660171259644,-0.7794292005641262,-0.1362485904097433,0.490236763907363,0.25375565145434276,-0.02190402285820215,1.471397176367932,-0.7148241860051961,0.30722341578558393,0.9806125526787869,0.5667757956444454,-1.2187064928309388,-0.02190402285820215,-0.7470323872777213,-0.5878385067985065,1.7608315718187155,0.11769676093724667,0.006307474011367515,2.2029028392455228,0.862258844628111,1.407171519295945,-0.682802624960496,0.8382620619356581,-1.1488380282478365,0.3601597156898264,1.679809873082842,-1.507173381664675,1.0039634351651625,0.22681944749468783,-0.6509657620201212,-0.050263952997597124,0.5667757956444454,4.144687074033624,0.3601597156898264,2.840232108692598,3.197933935950603	3367
Snare interactions in vesicular transport	8	11	2.092560294096447	0.0363884241446708	O15400,Q86Y82,Q12846,O43752,Q9P2W9,Q13190,Q9UNK0,O95721	Processes and pathways	KEGG Pathways	msigdb_kegg	626,459,452,206,81,365,678,122	626,1037,206,1807,122,452,795,365,459,81,678	0.5920441322650274,0.2805565672472788,1.4286699849010147,-0.1362485904097433,1.9963496087227715,0.8141544886580385,0.46447550012638145,0.9571562106244959,0.8141544886580385,2.436398337597714,0.5667757956444454	3367
Snap receptor activity	8	11	2.092560294096447	0.0363884241446708	O15400,Q86Y82,Q12846,O43752,Q9P2W9,Q13190,Q9UNK0,O95721	Functions	GO Molecular function	msigdb_gomf	626,459,452,206,81,365,678,122	626,1037,206,1807,122,452,795,365,459,81,678	0.5920441322650274,0.2805565672472788,1.4286699849010147,-0.1362485904097433,1.9963496087227715,0.8141544886580385,0.46447550012638145,0.9571562106244959,0.8141544886580385,2.436398337597714,0.5667757956444454	3367
Metalloprotease	6	24	2.09178214744673	0.0364580080660679	O75844,P42892,Q9BYT8,Q96KP4,Q9NZ08,P55786	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	68,35,151,183,156,93	1921,750,2647,68,403,896,2651,3121,1930,35,1589,93,658,2468,183,522,151,2377,2564,2962,2322,156,228,1133	-0.19434031752410985,0.490236763907363,-0.6193116841420223,2.6926945390869426,0.8861457519054411,0.38643153062342506,-0.6193116841420223,-1.1836636419604167,-0.19434031752410985,3.2722740469256966,-0.02190402285820215,2.294021415669942,0.5667757956444454,-0.4637180795900233,1.5137692083085525,0.7165975954483155,1.7608315718187155,-0.40269627647094874,-0.525427454868466,-0.9109430815275097,-0.3724389183184647,1.7406977485275759,1.3421283755465698,0.25375565145434276	3367
Atpase coupled transmembrane transporter activity	6	17	2.08962450942148	0.0366515430889744	Q9HD20,P51798,P08183,O75027,P06576,P16615	Functions	GO Molecular function	msigdb_gomf	165,71,146,211,250,305	963,211,1213,250,146,305,927,548,2897,855,970,2498,71,2502,165,1509,341	0.3337574021162552,1.3855822269020739,0.17253621044918402,1.231854696356683,1.7808852976154201,1.0503522207387042,0.3601597156898264,0.6671297810793578,-0.8447967022235733,0.41257400595833643,0.3337574021162552,-0.49448594888254555,2.6256544201008225,-0.49448594888254555,1.6388066898289295,0.03437193328851483,1.0039634351651625	3367
Endocytic vesicle	25	82	2.0776928104977217	0.0377376616604367	O15400,Q14108,Q8WTV0,Q93050,P08670,P04439,Q9UNK0,P02786,P13473,Q9Y5K6,Q9H1C4,O00461,Q9Y4G8,Q16625,O14964,Q5KU26,Q86Y82,Q12846,O43752,Q9H223,Q9Y487,P10321,P01889,P42345,P20645	Localization	GO Cellular component	msigdb_gocc	626,6,9,265,390,389,678,529,161,570,174,51,59,188,434,193,459,452,206,338,358,229,598,601,251	2529,1990,2486,51,434,626,963,206,3221,3004,1807,1809,2055,598,529,389,648,390,1214,2617,229,1577,1039,816,161,1418,1758,251,2538,1044,757,601,1145,1822,1182,2235,2976,1269,2449,2836,2129,2130,2502,3267,2133,1535,1707,3046,452,2456,2013,1770,2981,6,691,1381,2247,2411,2077,188,1954,193,1107,1385,2599,459,9,2421,265,1608,1158,1910,174,338,1512,2042,2043,678,358,59,1081,570	-0.525427454868466,-0.2236212584096826,-0.49448594888254555,2.983395828585835,0.8382620619356581,0.5920441322650274,0.3337574021162552,1.4286699849010147,-1.4336660463047972,-0.977885243317303,-0.1362485904097433,-0.1362485904097433,-0.2530609609086133,0.6171918880980484,0.6919219483408452,0.9099236880488443,0.5667757956444454,0.9099236880488443,0.17253621044918402,-0.5878385067985065,1.3202624041063196,-0.02190402285820215,0.2805565672472788,0.4385882859122563,1.679809873082842,0.062290731757696595,-0.1074347923116181,1.231854696356683,-0.525427454868466,0.2805565672472788,0.490236763907363,0.6171918880980484,0.22681944749468783,-0.1362485904097433,0.19974671831673846,-0.34234834725948426,-0.9443136123937819,0.1451866537146581,-0.4637180795900233,-0.7794292005641262,-0.2826609847711293,-0.2826609847711293,-0.49448594888254555,-1.5816442855181783,-0.2826609847711293,0.006307474011367515,-0.07877373131780484,-1.011660171259644,0.8141544886580385,-0.4637180795900233,-0.2236212584096826,-0.1074347923116181,-0.9443136123937819,4.383005400114565,0.5413858311413456,0.09006522764362623,-0.34234834725948426,-0.4331220969912666,-0.2530609609086133,1.4926272539284748,-0.19434031752410985,1.471397176367932,0.25375565145434276,0.09006522764362623,-0.5565443734227432,0.8141544886580385,4.324586732934785,-0.4331220969912666,1.187074181061587,-0.02190402285820215,0.22681944749468783,-0.16521660034488708,1.5766728741783365,1.0039634351651625,0.03437193328851483,-0.2236212584096826,-0.2236212584096826,0.5667757956444454,0.9806125526787869,2.840232108692598,0.2805565672472788,0.6671297810793578	3367
Delusions	9	22	2.072182281078002	0.0382484452010893	Q96DF8,Q9BQE5,Q9UJS0,Q96RL7,O00754,P07602,Q9NZJ7,P04062,P21964	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	130,3,677,700,543,113,641,56,285	543,1454,56,113,2799,1634,285,2582,2291,999,2126,1585,1898,2015,3065,130,700,3,777,641,2568,677	0.6671297810793578,0.03437193328851483,2.888427682882454,2.110076974296961,-0.7470323872777213,-0.050263952997597124,1.1191654406700127,-0.5565443734227432,-0.3724389183184647,0.30722341578558393,-0.2826609847711293,-0.02190402285820215,-0.16521660034488708,-0.2236212584096826,-1.0456406280505959,1.9384991366690936,0.5413858311413456,4.54267192090626,0.490236763907363,0.5920441322650274,-0.525427454868466,0.5667757956444454	3367
Signaling	9	17	2.0676409936236104	0.0386737942858297	P43490,Q96PC5,Q96GC9,Q99627,P42166,O00264,O15173,Q8WUJ1,Q13123	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	257,832,875,446,333,304,118,312,796	304,118,1358,2340,333,257,2006,1833,796,1106,1546,312,875,910,832,446,1680	1.0503522207387042,2.0535377021037875,0.09006522764362623,-0.40269627647094874,1.0039634351651625,1.2095131214680288,-0.2236212584096826,-0.1362485904097433,0.46447550012638145,0.25375565145434276,0.006307474011367515,1.0503522207387042,0.41257400595833643,0.38643153062342506,0.4385882859122563,0.8382620619356581,-0.050263952997597124	3367
Submucous cleft of soft and hard palate	8	26	2.064424129207946	0.0389775206458038	Q99741,Q96DF8,O75844,Q9Y2W2,Q15392,Q7LGA3,Q2M1P5,O43505	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	327,130,68,343,79,239,246,87	2283,711,87,68,1522,2399,2583,1821,687,1766,2872,1475,3101,1054,1103,1275,79,246,1845,239,353,3065,130,327,343,3250	-0.3724389183184647,0.5158731784643796,2.3478963961729225,2.6926945390869426,0.006307474011367515,-0.4331220969912666,-0.5565443734227432,-0.1362485904097433,0.5413858311413456,-0.1074347923116181,-0.8120166279085533,0.03437193328851483,-1.1142272342228774,0.2805565672472788,0.25375565145434276,0.1451866537146581,2.471357400586925,1.254099665260839,-0.1362485904097433,1.2762487791777117,0.9806125526787869,-1.0456406280505959,1.9384991366690936,1.0272097103903832,1.0039634351651625,-1.4703006768417601	3367
Mitochondrial nucleotide transporter subfamily	6	9	2.0606828252742857	0.0393333091969749	Q6NUK1,Q9HC21,Q70HW3,Q9BSK2,P12236,Q9H2D1	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	660,107,77,314,361,86	645,995,1040,361,660,77,314,86,107	0.5667757956444454,0.30722341578558393,0.2805565672472788,0.9571562106244959,0.5667757956444454,2.5060688955133497,1.0503522207387042,2.3657246319376566,2.165980585241542	3367
Abnormality of the 5th toe	6	7	2.059777368642854	0.0394198290682736	Q14739,Q10713,Q9Y263,Q2M1P5,Q9UBM7,Q8IYA6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,655,173,246,185,634	655,289,246,634,801,185,173	0.5667757956444454,1.1191654406700127,1.254099665260839,0.5920441322650274,0.46447550012638145,1.5137692083085525,1.5974688426783576	3367
Dementia	12	61	2.05941122308977	0.039454861535763	P05067,P06865,Q13510,Q14108,O15118,O60313,P07602,Q9NQZ5,P35637,P04062,Q9Y487,P17900	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	160,347,101,6,96,359,113,117,332,56,358,221	747,96,1454,359,2052,628,1361,718,56,3276,2121,160,347,113,2861,2862,1634,221,1175,2001,2341,1635,756,3142,2865,332,970,2498,999,1423,1328,2178,3013,2008,2356,1100,1273,2359,657,101,6,865,2250,1777,1012,1115,871,1392,520,2780,1344,700,1611,3314,117,641,387,1624,2889,358,2918	0.490236763907363,2.2759315653971224,0.03437193328851483,0.9571562106244959,-0.2530609609086133,0.5920441322650274,0.09006522764362623,0.5158731784643796,2.888427682882454,-1.6192482414532234,-0.2826609847711293,1.7001874873242686,0.9806125526787869,2.110076974296961,-0.8120166279085533,-0.8120166279085533,-0.050263952997597124,1.3639014130956277,0.19974671831673846,-0.2236212584096826,-0.40269627647094874,-0.050263952997597124,0.490236763907363,-1.2187064928309388,-0.8120166279085533,1.0039634351651625,0.3337574021162552,-0.49448594888254555,0.30722341578558393,0.062290731757696595,0.11769676093724667,-0.31242291199836886,-0.977885243317303,-0.2236212584096826,-0.40269627647094874,0.25375565145434276,0.1451866537146581,-0.40269627647094874,0.5667757956444454,2.2395519580884713,4.383005400114565,0.41257400595833643,-0.34234834725948426,-0.1074347923116181,0.30722341578558393,0.25375565145434276,0.41257400595833643,0.09006522764362623,0.7165975954483155,-0.7148241860051961,0.11769676093724667,0.5413858311413456,-0.02190402285820215,-1.929324312075685,2.072455559506005,0.5920441322650274,0.9335935466195544,-0.02190402285820215,-0.8120166279085533,0.9806125526787869,-0.8447967022235733	3367
Abnormality of the septum pellucidum	13	47	2.049905614967365	0.0403736421750484	Q6P1N0,O14974,Q96N66,O96028,Q71SY5,Q15392,P53701,Q2M1P5,Q9UJX6,O43505,Q2M389,O95202,Q8N3U4	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	258,231,137,236,78,79,363,246,254,87,310,330,353	231,711,87,2329,330,236,630,2581,1526,1821,2543,363,2236,1475,1895,2953,2409,1103,2073,1275,79,246,310,1903,258,1281,78,353,1390,2466,1496,2556,1157,137,3069,432,1558,2816,564,1202,1129,1406,2384,254,2966,2919,3250	1.2983027806935246,0.5158731784643796,2.3478963961729225,-0.40269627647094874,1.0039634351651625,1.2762487791777117,0.5920441322650274,-0.5565443734227432,0.006307474011367515,-0.1362485904097433,-0.525427454868466,0.9571562106244959,-0.34234834725948426,0.03437193328851483,-0.16521660034488708,-0.9109430815275097,-0.4331220969912666,0.25375565145434276,-0.2530609609086133,0.1451866537146581,2.471357400586925,1.254099665260839,1.0503522207387042,-0.16521660034488708,1.2095131214680288,0.1451866537146581,2.4887438961354635,0.9806125526787869,0.09006522764362623,-0.4637180795900233,0.03437193328851483,-0.525427454868466,0.22681944749468783,1.8603105982788577,-1.0456406280505959,0.862258844628111,0.006307474011367515,-0.7470323872777213,0.6671297810793578,0.19974671831673846,0.25375565145434276,0.09006522764362623,-0.40269627647094874,1.231854696356683,-0.9109430815275097,-0.8447967022235733,-1.4703006768417601	3367
Lipase activity	7	17	2.048396828932699	0.0405211320075915	Q9H6V9,Q8NCC3,Q8IV08,Q8NHP8,P09601,Q8N2K0,Q8N2A8	Functions	GO Molecular function	msigdb_gomf	67,10,441,49,21,442,259	3159,21,818,1759,1044,3228,3133,441,1115,259,442,518,10,49,67,1204,1684	-1.2539690378581203,3.613683844728898,0.4385882859122563,-0.1074347923116181,0.2805565672472788,-1.4336660463047972,-1.1836636419604167,0.8382620619356581,0.25375565145434276,1.2095131214680288,0.8382620619356581,0.7165975954483155,4.301006972369739,3.045680587864037,2.709311108656073,0.19974671831673846,-0.050263952997597124	3367
Hexosyltransferase activity	13	32	2.048039661573128	0.0405561133253444	Q10471,Q10472,Q9BT22,P06865,Q13126,P04844,P04843,O43505,Q96L58,Q6ZXV5,P04062,Q2TAA5,P46977	Functions	GO Molecular function	msigdb_gomf	654,308,292,347,41,719,572,87,410,149,56,222,686	1800,709,87,2286,1572,2825,56,572,719,1139,347,2649,1812,1041,1935,3229,686,1148,2356,654,308,41,222,149,1285,1286,1235,908,410,292,2157,1739	-0.1362485904097433,0.5158731784643796,2.3478963961729225,-0.3724389183184647,-0.02190402285820215,-0.7794292005641262,2.888427682882454,0.6422200972561323,0.5158731784643796,0.22681944749468783,0.9806125526787869,-0.6193116841420223,-0.1362485904097433,0.2805565672472788,-0.19434031752410985,-1.4336660463047972,0.5413858311413456,0.22681944749468783,-0.40269627647094874,0.5667757956444454,1.0503522207387042,3.227809668601115,1.3639014130956277,1.7608315718187155,0.1451866537146581,0.1451866537146581,0.17253621044918402,0.38643153062342506,0.8861457519054411,1.1191654406700127,-0.2826609847711293,-0.07877373131780484	3367
Establishment of protein localization to vacuole	8	18	2.040754752626098	0.0412752100877225	P13473,O00203,Q9H9H4,Q14108,P46934,Q9BRG1,P20645,O14964	Processes and pathways	GO Biological process	msigdb_gobp	161,473,401,6,419,638,251,434	473,1515,434,1757,161,251,419,2235,6,1012,942,1602,700,1158,638,401,3157,918	0.7656032541864601,0.006307474011367515,0.8382620619356581,-0.1074347923116181,1.679809873082842,1.231854696356683,0.862258844628111,-0.34234834725948426,4.383005400114565,0.30722341578558393,0.3601597156898264,-0.02190402285820215,0.5413858311413456,0.22681944749468783,0.5920441322650274,0.9099236880488443,-1.2187064928309388,0.38643153062342506	3367
Endocytic vesicle membrane	10	40	2.038007099919225	0.0415492228340923	P13473,Q5KU26,Q14108,P10321,Q93050,Q8WTV0,Q12846,P04439,Q9Y487,P20645	Localization	GO Cellular component	msigdb_gocc	161,193,6,229,265,9,452,389,358,251	2486,963,1807,1809,2055,598,529,389,229,1039,816,161,1758,251,2538,1145,2235,1269,2836,2129,2502,2133,1535,1707,3046,452,1770,2981,6,2247,2411,193,1385,9,265,1608,1158,1910,2042,358	-0.49448594888254555,0.3337574021162552,-0.1362485904097433,-0.1362485904097433,-0.2530609609086133,0.6171918880980484,0.6919219483408452,0.9099236880488443,1.3202624041063196,0.2805565672472788,0.4385882859122563,1.679809873082842,-0.1074347923116181,1.231854696356683,-0.525427454868466,0.22681944749468783,-0.34234834725948426,0.1451866537146581,-0.7794292005641262,-0.2826609847711293,-0.49448594888254555,-0.2826609847711293,0.006307474011367515,-0.07877373131780484,-1.011660171259644,0.8141544886580385,-0.1074347923116181,-0.9443136123937819,4.383005400114565,-0.34234834725948426,-0.4331220969912666,1.471397176367932,0.09006522764362623,4.324586732934785,1.187074181061587,-0.02190402285820215,0.22681944749468783,-0.16521660034488708,-0.2236212584096826,0.9806125526787869	3367
Hydrogen ion transport	7	18	2.0316199835096427	0.0421921420564488	Q93050,Q9UI12,O75964,P56385,Q15904,Q9Y487,P06576	Processes and pathways	Protein Atlas Biological process	protein_atlas_biological_process	265,341,17,214,182,358,250	851,17,250,548,2897,378,1580,759,970,2498,2928,2296,214,2502,182,265,341,358	0.41257400595833643,3.867353512797234,1.231854696356683,0.6671297810793578,-0.8447967022235733,0.9335935466195544,-0.02190402285820215,0.490236763907363,0.3337574021162552,-0.49448594888254555,-0.8777714879158465,-0.3724389183184647,1.3855822269020739,-0.49448594888254555,1.5137692083085525,1.187074181061587,1.0039634351651625,0.9806125526787869	3367
Hydrolase activity acting on glycosyl bonds	11	33	2.0282727683710644	0.0425324166557878	P06280,P16278,O60476,P04066,P54802,P10253,O00462,P04062,O75503,P17900,O60502	Functions	GO Molecular function	msigdb_gomf	255,5,249,319,109,269,180,56,57,221,62	180,543,2488,249,62,57,56,319,255,347,2649,269,2699,649,5,221,1176,3140,899,1935,109,2547,2356,2183,2593,610,1282,2084,3358,1730,1028,2964,3002	1.5137692083085525,0.6671297810793578,-0.49448594888254555,1.231854696356683,2.7588221406548605,2.8563508480242543,2.888427682882454,1.0272097103903832,1.2095131214680288,0.9806125526787869,-0.6193116841420223,1.164537106940616,-0.6509657620201212,0.5667757956444454,4.4292036485047825,1.3639014130956277,0.19974671831673846,-1.2187064928309388,0.38643153062342506,-0.19434031752410985,2.1474158808446684,-0.525427454868466,-0.40269627647094874,-0.31242291199836886,-0.5565443734227432,0.6171918880980484,0.1451866537146581,-0.2530609609086133,-3.5732130897558765,-0.07877373131780484,0.30722341578558393,-0.9109430815275097,-0.9443136123937819	3367
Reductase	6	16	2.024664660191364	0.0429018097863949	Q9H7Z7,Q9UDW1,Q15392,O95881,Q9UBM7,P00374	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	65,112,79,82,185,63	3301,1359,1876,82,63,2923,2763,2864,652,1178,289,79,2845,65,185,112	-1.8110727649287937,0.09006522764362623,-0.16521660034488708,2.418824969229302,2.7588221406548605,-0.8777714879158465,-0.7148241860051961,-0.8120166279085533,0.5667757956444454,0.19974671831673846,1.1191654406700127,2.471357400586925,-0.7794292005641262,2.742374563169135,1.5137692083085525,2.1287815015903986	3367
Transmembrane transport	57	187	2.023317955795705	0.0430403768153886	Q9NS69,P24539,O43615,O14925,Q15043,Q8WTV0,Q15629,O75964,P08183,Q99623,Q8IYU8,Q13423,P45880,P27105,P05067,Q99595,Q9Y277,P21796,Q9HD20,P41440,Q15041,O43772,O60830,Q9UHG3,Q9UJZ1,Q6NT16,Q9BSK2,P04062,Q99996,P16615,Q16625,O75844,Q8IXU6,P51798,P78417,P13073,Q70HW3,P23786,Q9UI12,Q9C0H2,P56385,Q8NE01,P30825,Q9H2D1,P35754,O95202,O75027,Q9UBX3,O43933,P62942,Q9HC21,Q6P4Q7,Q9UDW1,P12236,P06576,Q99442,Q8TB61	Processes and pathways	GO Biological process	msigdb_gobp	0,378,376,262,263,9,11,17,146,282,150,278,29,157,160,37,166,34,165,167,295,169,47,48,317,178,314,56,184,305,188,68,70,71,72,73,77,207,341,80,214,335,85,86,213,330,211,91,92,97,107,369,112,361,250,383,125	3092,1990,2756,1746,961,262,376,1085,169,645,92,2118,47,1517,211,3200,2758,2793,713,2647,508,68,1873,851,17,2761,330,545,2575,716,1361,718,56,1213,160,995,1877,250,1697,1879,1810,146,1091,1756,3263,2060,1999,1215,1462,1632,1040,361,73,305,818,927,819,548,2897,3111,34,207,378,1580,157,3140,969,855,3240,3125,85,574,3193,2175,213,759,970,1366,2498,167,999,29,419,1047,1889,2928,511,512,1181,1145,71,2446,1590,553,1824,792,2236,2296,214,3356,3128,1704,2502,2237,1098,97,72,1186,1223,974,3114,1273,863,1947,278,764,2981,1476,1839,295,263,2411,11,1433,2248,188,2018,178,660,2192,369,1011,2599,77,1601,1490,70,150,1720,335,1604,125,2310,9,1196,698,875,2603,521,383,3314,37,282,470,184,948,314,591,669,400,80,622,86,2785,1972,1561,1307,107,165,2207,1509,0,2606,91,112,743,1680,48,341,677,317,1512,166,1033,1452,1133,3137	-1.1142272342228774,-0.2236212584096826,-0.7148241860051961,-0.1074347923116181,0.3337574021162552,1.187074181061587,0.9335935466195544,0.25375565145434276,1.5974688426783576,0.5667757956444454,2.294021415669942,-0.2826609847711293,3.107165693020846,0.006307474011367515,1.3855822269020739,-1.3611000187999303,-0.7148241860051961,-0.7470323872777213,0.5158731784643796,-0.6193116841420223,0.7165975954483155,2.6926945390869426,-0.16521660034488708,0.41257400595833643,3.867353512797234,-0.7148241860051961,1.0039634351651625,0.6671297810793578,-0.5565443734227432,0.5158731784643796,0.09006522764362623,0.5158731784643796,2.888427682882454,0.17253621044918402,1.7001874873242686,0.30722341578558393,-0.16521660034488708,1.231854696356683,-0.07877373131780484,-0.16521660034488708,-0.1362485904097433,1.7808852976154201,0.25375565145434276,-0.1074347923116181,-1.5816442855181783,-0.2530609609086133,-0.2236212584096826,0.17253621044918402,0.03437193328851483,-0.050263952997597124,0.2805565672472788,0.9571562106244959,2.5747617035953736,1.0503522207387042,0.4385882859122563,0.3601597156898264,0.4385882859122563,0.6671297810793578,-0.8447967022235733,-1.1488380282478365,3.2722740469256966,1.4286699849010147,0.9335935466195544,-0.02190402285820215,1.7204832487252557,-1.2187064928309388,0.3337574021162552,0.41257400595833643,-1.4703006768417601,-1.1836636419604167,2.3834885282361222,0.6422200972561323,-1.3251632411413339,-0.31242291199836886,1.3855822269020739,0.490236763907363,0.3337574021162552,0.09006522764362623,-0.49448594888254555,1.6181799067894833,0.30722341578558393,3.403217513344748,0.862258844628111,0.2805565672472788,-0.16521660034488708,-0.8777714879158465,0.7165975954483155,0.7165975954483155,0.19974671831673846,0.22681944749468783,2.6256544201008225,-0.4637180795900233,-0.02190402285820215,0.6671297810793578,-0.1362485904097433,0.46447550012638145,-0.34234834725948426,-0.3724389183184647,1.3855822269020739,-3.3665191515672723,-1.1836636419604167,-0.07877373131780484,-0.49448594888254555,-0.34234834725948426,0.25375565145434276,2.2759315653971224,2.59178502036956,0.19974671831673846,0.17253621044918402,0.3337574021162552,-1.1488380282478365,0.1451866537146581,0.41257400595833643,-0.19434031752410985,1.1419011221151822,0.490236763907363,-0.9443136123937819,0.03437193328851483,-0.1362485904097433,1.0963292676298746,1.187074181061587,-0.4331220969912666,4.156903668614397,0.062290731757696595,-0.34234834725948426,1.4926272539284748,-0.2236212584096826,1.5348236972160396,0.5667757956444454,-0.31242291199836886,0.9571562106244959,0.30722341578558393,-0.5565443734227432,2.5060688955133497,-0.02190402285820215,0.03437193328851483,2.64250124049558,1.7608315718187155,-0.07877373131780484,1.0039634351651625,-0.02190402285820215,1.9578570786990497,-0.3724389183184647,4.324586732934785,0.19974671831673846,0.5413858311413456,0.41257400595833643,-0.5565443734227432,0.7165975954483155,0.9335935466195544,-1.929324312075685,3.2722740469256966,1.1419011221151822,0.7899351985641869,1.5137692083085525,0.3601597156898264,1.0503522207387042,0.6422200972561323,0.5667757956444454,0.9099236880488443,2.4539090139419626,0.6171918880980484,2.3657246319376566,-0.7148241860051961,-0.19434031752410985,0.006307474011367515,0.1451866537146581,2.165980585241542,1.6388066898289295,-0.31242291199836886,0.03437193328851483,4.803828948758111,-0.5565443734227432,2.312045215706412,2.1287815015903986,0.5158731784643796,-0.050263952997597124,3.107165693020846,1.0039634351651625,0.5667757956444454,1.0503522207387042,0.03437193328851483,1.6388066898289295,0.30722341578558393,0.062290731757696595,0.25375565145434276,-1.1836636419604167	3367
Abnormal epiphyseal ossification	13	17	2.016799172912396	0.0437164753071983	Q14739,P56589,O00116,Q14807,Q96HA7,Q15125,Q9UG56,Q2M1P5,Q96HY6,Q96L58,Q9UBM7,O43933,O75381	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	289,533,571,821,831,177,742,246,281,410,185,92,713	571,92,3004,713,897,1366,533,289,821,177,2842,246,831,281,410,185,742	0.6422200972561323,2.294021415669942,-0.977885243317303,0.5158731784643796,0.38643153062342506,0.09006522764362623,0.6919219483408452,1.1191654406700127,0.4385882859122563,1.5348236972160396,-0.7794292005641262,1.254099665260839,0.4385882859122563,1.1419011221151822,0.8861457519054411,1.5137692083085525,0.5158731784643796	3367
Regulation of hormone levels	16	59	2.016465937502606	0.0437512765955157	Q53GQ0,Q8N183,P42892,O75844,Q15043,P16435,P80404,Q12846,P17858,P53985,O95563,Q9UBM7,Q9HB40,O95470,P30536,Q14849	Processes and pathways	GO Biological process	msigdb_gobp	351,129,35,68,263,293,234,452,495,553,545,185,58,123,124,31	1990,1516,1995,1927,68,123,545,2492,753,1213,1265,1930,2763,293,495,2002,124,3125,1819,35,3279,1181,1586,553,3014,2660,2665,234,3114,2839,452,1895,3101,1770,31,263,1277,1952,1190,351,582,1385,2599,2415,129,1017,1237,1604,2030,2603,1020,701,3314,3152,58,185,2967,643,2281	-0.2236212584096826,0.006307474011367515,-0.2236212584096826,-0.19434031752410985,2.6926945390869426,1.9771403969263128,0.6671297810793578,-0.49448594888254555,0.490236763907363,0.17253621044918402,0.1451866537146581,-0.19434031752410985,-0.7148241860051961,1.0963292676298746,0.7411577066416265,-0.2236212584096826,1.9771403969263128,-1.1836636419604167,-0.1362485904097433,3.2722740469256966,-1.6192482414532234,0.19974671831673846,-0.02190402285820215,0.6671297810793578,-0.977885243317303,-0.6193116841420223,-0.6193116841420223,1.2983027806935246,-1.1488380282478365,-0.7794292005641262,0.8141544886580385,-0.16521660034488708,-1.1142272342228774,-0.1074347923116181,3.3454673481684774,1.187074181061587,0.1451866537146581,-0.19434031752410985,0.19974671831673846,0.9806125526787869,0.6422200972561323,0.09006522764362623,-0.5565443734227432,-0.4331220969912666,1.9384991366690936,0.30722341578558393,0.17253621044918402,-0.02190402285820215,-0.2236212584096826,-0.5565443734227432,0.30722341578558393,0.5413858311413456,-1.929324312075685,-1.2187064928309388,2.840232108692598,1.5137692083085525,-0.9109430815275097,0.5920441322650274,-0.34234834725948426	3367
Organelle membrane contact site	6	14	2.014945657368127	0.0439103433426273	Q5XKP0,Q96N66,P51572,Q96TC7,A0FGR8,Q14849	Localization	GO Cellular component	msigdb_gocc	581,137,238,313,680,31	680,1995,1361,1217,238,31,581,1292,1293,137,313,1158,1309,780	0.5413858311413456,-0.2236212584096826,0.09006522764362623,0.17253621044918402,1.2762487791777117,3.3454673481684774,0.6422200972561323,0.1451866537146581,0.1451866537146581,1.8603105982788577,1.0503522207387042,0.22681944749468783,0.1451866537146581,0.490236763907363	3367
Exaggerated startle response	6	9	2.0118159582934134	0.0442393410859782	P06865,P16278,Q9Y263,Q00577,P08243,P17900	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	347,5,173,535,154,221	347,2649,154,5,221,535,703,1308,173	0.9806125526787869,-0.6193116841420223,1.7406977485275759,4.4292036485047825,1.3639014130956277,0.6919219483408452,0.5413858311413456,0.1451866537146581,1.5974688426783576	3367
Trans golgi network membrane	8	24	2.011513121446564	0.0442712857689482	P05067,Q9UP83,P53367,O43752,Q9UID3,P53365,P20645,O15127	Localization	GO Cellular component	msigdb_gocc	160,375,141,206,542,147,251,435	847,435,1318,206,2219,160,1214,816,251,576,147,141,1183,2836,1826,1535,1894,2411,1482,2266,1557,542,375,2789	0.41257400595833643,0.8382620619356581,0.11769676093724667,1.4286699849010147,-0.34234834725948426,1.7001874873242686,0.17253621044918402,0.4385882859122563,1.231854696356683,0.6422200972561323,1.7808852976154201,1.820754742930303,0.19974671831673846,-0.7794292005641262,-0.1362485904097433,0.006307474011367515,-0.16521660034488708,-0.4331220969912666,0.03437193328851483,-0.34234834725948426,0.006307474011367515,0.6919219483408452,0.9571562106244959,-0.7148241860051961	3367
Establishment of protein localization to membrane	26	82	2.010097829521427	0.0444208357513724	Q9NS69,Q9H9H4,Q15629,P56589,P43307,P27105,P46379,Q96A33,Q9HD20,Q15041,O60725,Q15904,Q4J6C6,Q53H12,P31751,Q9Y276,O14737,Q9H4A6,O15118,O00203,P49458,Q9Y512,Q99442,Q15070,Q9P0J0,O00560	Processes and pathways	GO Biological process	msigdb_gobp	0,401,11,533,28,157,30,431,165,295,170,182,439,440,574,342,205,471,96,473,603,644,383,366,386,625	2529,473,625,205,1315,96,1454,1992,170,3159,1629,2761,1264,648,1929,2703,157,2290,3213,574,1934,2767,1584,28,30,2622,603,2235,1329,533,3356,3128,2836,1704,2129,2237,3216,935,1947,2456,2549,1480,295,2188,366,11,182,439,1842,440,2307,1658,1601,1602,1193,1547,1848,1196,431,1344,383,1910,2425,1125,471,1402,401,165,2207,0,884,386,743,992,1680,1566,3177,958,342,1452,644,2755	-0.525427454868466,0.7656032541864601,0.5920441322650274,1.4286699849010147,0.11769676093724667,2.2759315653971224,0.03437193328851483,-0.2236212584096826,1.5974688426783576,-1.2539690378581203,-0.050263952997597124,-0.7148241860051961,0.1451866537146581,0.5667757956444454,-0.19434031752410985,-0.6509657620201212,1.7204832487252557,-0.3724389183184647,-1.3972667312364715,0.6422200972561323,-0.19434031752410985,-0.7148241860051961,-0.02190402285820215,3.4175453651007617,3.3454673481684774,-0.5878385067985065,0.6171918880980484,-0.34234834725948426,0.11769676093724667,0.6919219483408452,-3.3665191515672723,-1.1836636419604167,-0.7794292005641262,-0.07877373131780484,-0.2826609847711293,-0.34234834725948426,-1.3972667312364715,0.3601597156898264,-0.19434031752410985,-0.4637180795900233,-0.525427454868466,0.03437193328851483,1.0963292676298746,-0.31242291199836886,0.9571562106244959,4.156903668614397,1.5137692083085525,0.8382620619356581,-0.1362485904097433,0.8382620619356581,-0.3724389183184647,-0.050263952997597124,-0.02190402285820215,-0.02190402285820215,0.19974671831673846,0.006307474011367515,-0.1362485904097433,0.19974671831673846,0.862258844628111,0.11769676093724667,0.9335935466195544,-0.16521660034488708,-0.4331220969912666,0.25375565145434276,0.7899351985641869,0.09006522764362623,0.9099236880488443,1.6388066898289295,-0.31242291199836886,4.803828948758111,0.41257400595833643,0.9335935466195544,0.5158731784643796,0.3337574021162552,-0.050263952997597124,0.006307474011367515,-1.2539690378581203,0.3601597156898264,1.0039634351651625,0.062290731757696595,0.5920441322650274,-0.682802624960496	3367
Positive regulation of peptidase activity	18	43	2.009593807705546	0.0444741971773432	P05067,Q9Y255,P40763,Q96A26,Q9NR28,P61289,Q9BXK5,P09429,P42575,O14737,P51572,P61604,Q92542,Q9NZJ7,Q96HY6,O95831,Q9P0J0,Q9UL46	Processes and pathways	GO Biological process	msigdb_gobp	160,100,632,132,196,321,374,417,549,205,238,605,218,641,281,716,386,356	1869,1921,1922,205,1357,2825,1873,2054,716,1574,160,417,1999,1176,632,549,1938,238,3013,321,605,3145,3216,1429,1829,2013,1005,2671,218,1019,132,1609,773,281,877,374,196,641,386,1407,1863,356,100	-0.16521660034488708,-0.19434031752410985,-0.19434031752410985,1.4286699849010147,0.09006522764362623,-0.7794292005641262,-0.16521660034488708,-0.2530609609086133,0.5158731784643796,-0.02190402285820215,1.7001874873242686,0.862258844628111,-0.2236212584096826,0.19974671831673846,0.5920441322650274,0.6671297810793578,-0.19434031752410985,1.2762487791777117,-0.977885243317303,1.0272097103903832,0.6171918880980484,-1.2187064928309388,-1.3972667312364715,0.062290731757696595,-0.1362485904097433,-0.2236212584096826,0.30722341578558393,-0.6193116841420223,1.3855822269020739,0.30722341578558393,1.9190660482263868,-0.02190402285820215,0.490236763907363,1.1419011221151822,0.41257400595833643,0.9571562106244959,1.471397176367932,0.5920441322650274,0.9335935466195544,0.09006522764362623,-0.1362485904097433,0.9806125526787869,2.2759315653971224	3367
Protein targeting to vacuole	6	17	2.0018360751399813	0.0453023646451351	P13473,Q9H9H4,Q14108,P46934,P20645,O14964	Processes and pathways	GO Biological process	msigdb_gobp	161,401,6,419,251,434	473,1515,434,1757,161,251,419,2235,6,1012,942,1602,700,1158,401,3157,918	0.7656032541864601,0.006307474011367515,0.8382620619356581,-0.1074347923116181,1.679809873082842,1.231854696356683,0.862258844628111,-0.34234834725948426,4.383005400114565,0.30722341578558393,0.3601597156898264,-0.02190402285820215,0.5413858311413456,0.22681944749468783,0.9099236880488443,-1.2187064928309388,0.38643153062342506	3367
Serine protease	9	30	2.001057935592613	0.0453861467585052	P67812,P10619,Q2T9J0,Q9H3G5,O14773,Q86UT6,P42785,P34913,Q9HB40	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	98,40,395,12,108,370,18,181,58	2216,108,40,2947,2899,181,1094,18,2542,1703,1002,932,98,1895,2774,2904,395,2877,370,442,3347,2469,1395,1908,12,58,1862,3237,2110,2114	-0.34234834725948426,2.1474158808446684,3.227809668601115,-0.9109430815275097,-0.8447967022235733,1.5137692083085525,0.25375565145434276,3.8282095648532786,-0.525427454868466,-0.07877373131780484,0.30722341578558393,0.3601597156898264,2.2759315653971224,-0.16521660034488708,-0.7148241860051961,-0.8447967022235733,0.9099236880488443,-0.8120166279085533,0.9571562106244959,0.8382620619356581,-2.559722816212025,-0.4637180795900233,0.09006522764362623,-0.16521660034488708,4.144687074033624,2.840232108692598,-0.1362485904097433,-1.4336660463047972,-0.2530609609086133,-0.2530609609086133	3367
Cell recognition	8	26	1.995607501576332	0.0459766623539814	P05067,Q14157,Q5KU26,Q8WTV0,Q9NQC3,P50991,P45880,P35613	Processes and pathways	GO Biological process	msigdb_gobp	160,288,193,9,106,392,29,286	2530,1354,2729,3292,160,2340,2122,451,286,3165,29,2804,2404,2868,392,1944,1333,2071,288,193,1280,9,1393,2154,106,1795	-0.525427454868466,0.09006522764362623,-0.682802624960496,-1.7335697222803168,1.7001874873242686,-0.40269627647094874,-0.2826609847711293,0.8141544886580385,1.1191654406700127,-1.2539690378581203,3.403217513344748,-0.7470323872777213,-0.4331220969912666,-0.8120166279085533,0.9099236880488443,-0.19434031752410985,0.11769676093724667,-0.2530609609086133,1.1191654406700127,1.471397176367932,0.1451866537146581,4.324586732934785,0.09006522764362623,-0.2826609847711293,2.1844760833621826,-0.1074347923116181	3367
Transporter	73	171	1.99528035283573	0.0460123115059558	O15400,P24539,P24390,Q9BQE5,Q15043,Q93050,P49755,O75746,Q00765,Q9UJS0,Q9UPT5,P08183,Q8TEX9,Q9UNK0,P13473,Q6NUK1,Q9UNZ2,O43808,Q9P253,Q12768,P41440,O43772,O60749,O60664,O95563,Q6NT16,P21281,Q9BSK2,Q92973,P53985,O00471,P16615,Q9C0E2,Q7Z3B4,Q86Y82,Q8IXU6,Q12846,Q70HW3,O43752,Q9UI12,Q9P2W9,P56385,Q9Y3B3,Q8N1F7,P30825,Q9H2D1,Q99808,O95202,Q9H0U3,O75027,Q9UBX3,Q9Y487,P17900,P52292,Q15070,Q14444,Q8TAG9,Q08379,O00203,P06576,Q9HC21,P51572,Q15075,Q9HD45,Q13190,Q9NZJ7,Q9BVK6,P12236,P49257,O95721,O00560,Q8TB61,Q15833	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	626,378,2,3,263,265,511,508,515,677,274,146,538,678,161,660,296,645,567,656,167,169,416,415,545,178,548,314,469,553,681,305,592,584,459,70,452,77,206,341,81,214,219,334,85,86,470,330,622,211,91,358,221,466,366,608,226,497,473,250,107,238,367,114,365,641,640,361,496,122,625,125,380	1990,473,681,625,2327,3327,1515,2328,1805,626,206,682,169,645,1135,415,2394,416,894,211,1627,508,851,1360,330,1753,964,1754,545,122,1361,1213,995,250,146,1091,1214,2617,1215,1039,1040,361,161,305,221,927,548,2897,2,378,1580,855,1886,85,1324,759,2975,2498,167,1180,1528,496,511,238,466,2657,1590,2835,2406,1269,553,2708,2067,792,2068,2236,3081,2296,1183,214,1146,2502,2237,2351,2133,934,1186,1535,515,1223,497,1894,656,2135,452,975,365,2013,1709,608,2016,263,366,367,2411,1433,380,3206,178,660,2192,77,584,459,70,334,2027,226,125,1850,538,1439,1782,909,803,2602,469,265,828,2935,3024,1344,1299,1300,1069,470,3,3271,314,640,592,622,1858,86,1972,1561,107,114,1509,1562,991,641,1979,567,81,2641,2325,91,341,2212,677,678,296,274,2385,1411,219,358,1988,1082,919	-0.2236212584096826,0.7656032541864601,0.5413858311413456,0.5920441322650274,-0.40269627647094874,-2.131961245664126,0.006307474011367515,-0.40269627647094874,-0.1362485904097433,0.5920441322650274,1.4286699849010147,0.5413858311413456,1.5974688426783576,0.5667757956444454,0.22681944749468783,0.862258844628111,-0.4331220969912666,0.862258844628111,0.38643153062342506,1.3855822269020739,-0.050263952997597124,0.7165975954483155,0.41257400595833643,0.09006522764362623,1.0039634351651625,-0.1074347923116181,0.3337574021162552,-0.1074347923116181,0.6671297810793578,1.9963496087227715,0.09006522764362623,0.17253621044918402,0.30722341578558393,1.231854696356683,1.7808852976154201,0.25375565145434276,0.17253621044918402,-0.5878385067985065,0.17253621044918402,0.2805565672472788,0.2805565672472788,0.9571562106244959,1.679809873082842,1.0503522207387042,1.3639014130956277,0.3601597156898264,0.6671297810793578,-0.8447967022235733,4.631429349052777,0.9335935466195544,-0.02190402285820215,0.41257400595833643,-0.16521660034488708,2.3834885282361222,0.11769676093724667,0.490236763907363,-0.9443136123937819,-0.49448594888254555,1.6181799067894833,0.19974671831673846,0.006307474011367515,0.7411577066416265,0.7165975954483155,1.2762487791777117,0.7899351985641869,-0.6193116841420223,-0.02190402285820215,-0.7794292005641262,-0.4331220969912666,0.1451866537146581,0.6671297810793578,-0.6509657620201212,-0.2530609609086133,0.46447550012638145,-0.2530609609086133,-0.34234834725948426,-1.0798288811157457,-0.3724389183184647,0.19974671831673846,1.3855822269020739,0.22681944749468783,-0.49448594888254555,-0.34234834725948426,-0.40269627647094874,-0.2826609847711293,0.3601597156898264,0.19974671831673846,0.006307474011367515,0.7165975954483155,0.17253621044918402,0.7411577066416265,-0.16521660034488708,0.5667757956444454,-0.2826609847711293,0.8141544886580385,0.3337574021162552,0.9571562106244959,-0.2236212584096826,-0.07877373131780484,0.6171918880980484,-0.2236212584096826,1.187074181061587,0.9571562106244959,0.9571562106244959,-0.4331220969912666,0.062290731757696595,0.9335935466195544,-1.3611000187999303,1.5348236972160396,0.5667757956444454,-0.31242291199836886,2.5060688955133497,0.6422200972561323,0.8141544886580385,2.64250124049558,1.0039634351651625,-0.2236212584096826,1.3421283755465698,1.9578570786990497,-0.1362485904097433,0.6919219483408452,0.062290731757696595,-0.1074347923116181,0.38643153062342506,0.46447550012638145,-0.5565443734227432,0.7899351985641869,1.187074181061587,0.4385882859122563,-0.8777714879158465,-0.977885243317303,0.11769676093724667,0.1451866537146581,0.1451866537146581,0.2805565672472788,0.7899351985641869,4.54267192090626,-1.5816442855181783,1.0503522207387042,0.5920441322650274,0.6422200972561323,0.6171918880980484,-0.1362485904097433,2.3657246319376566,-0.19434031752410985,0.006307474011367515,2.165980585241542,2.110076974296961,0.03437193328851483,0.006307474011367515,0.3337574021162552,0.5920441322650274,-0.19434031752410985,0.6671297810793578,2.436398337597714,-0.5878385067985065,-0.3724389183184647,2.312045215706412,1.0039634351651625,-0.31242291199836886,0.5667757956444454,0.5667757956444454,1.0963292676298746,1.164537106940616,-0.40269627647094874,0.09006522764362623,1.3855822269020739,0.9806125526787869,-0.19434031752410985,0.2805565672472788,0.38643153062342506	3367
Organic hydroxy compound biosynthetic process	10	58	1.9921837613079607	0.0463508992783034	Q14739,Q16850,Q13510,Q15392,Q15800,Q15125,P04062,Q9UBM7,Q9Y4G8,P00374	Processes and pathways	GO Biological process	msigdb_gobp	289,131,101,79,110,177,56,185,59,63	3158,2116,2048,2328,448,1317,1625,1808,63,3182,56,2057,2438,1632,1633,293,2829,2002,2579,855,2582,2803,2619,2125,2769,930,1763,2349,2660,1331,3231,1050,1226,101,3019,938,289,177,2985,79,2842,110,1952,131,1609,1344,1241,3314,3152,880,1245,2104,1203,185,2483,1512,59,3250	-1.2539690378581203,-0.2826609847711293,-0.2530609609086133,-0.40269627647094874,0.8141544886580385,0.11769676093724667,-0.050263952997597124,-0.1362485904097433,2.7588221406548605,-1.2894537744189682,2.888427682882454,-0.2530609609086133,-0.4637180795900233,-0.050263952997597124,-0.050263952997597124,1.0963292676298746,-0.7794292005641262,-0.2236212584096826,-0.5565443734227432,0.41257400595833643,-0.5565443734227432,-0.7470323872777213,-0.5878385067985065,-0.2826609847711293,-0.7148241860051961,0.3601597156898264,-0.1074347923116181,-0.40269627647094874,-0.6193116841420223,0.11769676093724667,-1.4336660463047972,0.2805565672472788,0.17253621044918402,2.2395519580884713,-0.977885243317303,0.3601597156898264,1.1191654406700127,1.5348236972160396,-0.9443136123937819,2.471357400586925,-0.7794292005641262,2.1287815015903986,-0.19434031752410985,1.9190660482263868,-0.02190402285820215,0.11769676093724667,0.17253621044918402,-1.929324312075685,-1.2187064928309388,0.41257400595833643,0.17253621044918402,-0.2530609609086133,0.19974671831673846,1.5137692083085525,-0.4637180795900233,0.03437193328851483,2.840232108692598,-1.4703006768417601	3367
Myoclonus	15	98	1.9900730033498049	0.0465828941957984	P05067,Q13510,P50897,Q14108,P13073,Q9UBX3,O14773,P07602,Q9NQZ5,Q9NPL8,P04062,O75503,Q9Y4G8,P00374,Q96CU9	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	160,101,38,6,73,91,108,113,117,152,56,57,59,63,126	1746,2824,108,1991,2613,849,57,2396,2335,896,3222,1361,63,718,56,3276,160,113,2438,1215,73,1699,548,2735,756,2174,3142,1143,3226,2975,2498,999,2232,3265,2348,38,1328,2659,2869,1330,1705,2625,535,1535,168,904,1536,2838,2839,655,2873,3168,101,765,6,2809,2984,728,1482,2844,662,2845,1064,1848,1660,563,126,1608,1725,773,2637,2200,2266,1665,1611,2033,1123,3134,1399,950,1972,1973,152,1308,117,1203,1738,1029,2640,641,91,1865,1567,1624,2889,59,1133,3250	-0.1074347923116181,-0.7794292005641262,2.1474158808446684,-0.2236212584096826,-0.5878385067985065,0.41257400595833643,2.8563508480242543,-0.4331220969912666,-0.40269627647094874,0.38643153062342506,-1.4336660463047972,0.09006522764362623,2.7588221406548605,0.5158731784643796,2.888427682882454,-1.6192482414532234,1.7001874873242686,2.110076974296961,-0.4637180795900233,0.17253621044918402,2.5747617035953736,-0.07877373131780484,0.6671297810793578,-0.682802624960496,0.490236763907363,-0.31242291199836886,-1.2187064928309388,0.22681944749468783,-1.4336660463047972,-0.9443136123937819,-0.49448594888254555,0.30722341578558393,-0.34234834725948426,-1.5816442855181783,-0.40269627647094874,3.2574988008466623,0.11769676093724667,-0.6193116841420223,-0.8120166279085533,0.11769676093724667,-0.07877373131780484,-0.5878385067985065,0.6919219483408452,0.006307474011367515,1.6181799067894833,0.38643153062342506,0.006307474011367515,-0.7794292005641262,-0.7794292005641262,0.5667757956444454,-0.8120166279085533,-1.2539690378581203,2.2395519580884713,0.490236763907363,4.383005400114565,-0.7470323872777213,-0.9443136123937819,0.5158731784643796,0.03437193328851483,-0.7794292005641262,0.5667757956444454,-0.7794292005641262,0.2805565672472788,-0.1362485904097433,-0.050263952997597124,0.6671297810793578,1.9578570786990497,-0.02190402285820215,-0.07877373131780484,0.490236763907363,-0.5878385067985065,-0.31242291199836886,-0.34234834725948426,-0.050263952997597124,-0.02190402285820215,-0.2236212584096826,0.25375565145434276,-1.1836636419604167,0.09006522764362623,0.3601597156898264,-0.19434031752410985,-0.19434031752410985,1.7608315718187155,0.1451866537146581,2.072455559506005,0.19974671831673846,-0.07877373131780484,0.30722341578558393,-0.5878385067985065,0.5920441322650274,2.312045215706412,-0.1362485904097433,0.006307474011367515,-0.02190402285820215,-0.8120166279085533,2.840232108692598,0.25375565145434276,-1.4703006768417601	3367
Phospholipase activity	6	15	1.985991076542372	0.0470343147572283	Q8NCC3,Q8NHP8,Q8IV08,P09601,Q8N2K0,Q8N2A8	Functions	GO Molecular function	msigdb_gomf	10,49,441,21,442,259	3159,21,818,1759,1044,3133,441,1115,259,442,518,10,49,1204,1684	-1.2539690378581203,3.613683844728898,0.4385882859122563,-0.1074347923116181,0.2805565672472788,-1.1836636419604167,0.8382620619356581,0.25375565145434276,1.2095131214680288,0.8382620619356581,0.7165975954483155,4.301006972369739,3.045680587864037,0.19974671831673846,-0.050263952997597124	3367
Cellular monovalent inorganic cation homeostasis	7	23	1.9849550235260964	0.0471494757121979	P50897,Q93050,P06576,Q9UI12,Q15904,O75503,Q8N511	Processes and pathways	GO Biological process	msigdb_gobp	38,265,250,341,182,57,90	57,814,1213,250,3263,2704,2581,38,2235,792,2236,2502,1536,182,90,803,265,828,521,1680,341,358,3137	2.8563508480242543,0.4385882859122563,0.17253621044918402,1.231854696356683,-1.5816442855181783,-0.6509657620201212,-0.5565443734227432,3.2574988008466623,-0.34234834725948426,0.46447550012638145,-0.34234834725948426,-0.49448594888254555,0.006307474011367515,1.5137692083085525,2.33000339930892,0.46447550012638145,1.187074181061587,0.4385882859122563,0.7165975954483155,-0.050263952997597124,1.0039634351651625,0.9806125526787869,-1.1836636419604167	3367