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term	overlap	setsize	score	pval	edge	type	subtype	subtype_key	edge_idxs	ann_idxs	ann_vals	sig_size
Lysosome	32	51	5.359993126342884	8.322511842194988e-08	Q8NCC3,P10253,O14773,O75503,P11279,P50897,P13473,P11717,Q14108,P07602,P11117,P20645,Q99538,O15118,Q9Y487,Q93050,P54802,O00462,P06280,P16278,Q9NZJ7,P15586,P06865,Q13510,O00754,P04062,P04066,P61916,P10619,P17900,P07686,Q15904	Processes and pathways	KEGG Pathways	msigdb_kegg	0,143,20,24,150,29,30,156,32,34,37,44,177,46,186,62,65,66,67,68,222,85,84,90,208,210,94,99,106,107,119,126	1713,66,208,1465,20,46,2814,1891,24,210,94,67,84,34,119,1897,795,143,106,37,150,156,30,633,85,68,107,44,2876,29,869,65,1746,1011,99,1232,1838,90,32,126,0,2118,62,177,2568,222,249,2857,3077,412,186	-0.07503752950409251,2.5831453876103505,1.2109881782657737,0.05307774962454346,3.9953969719732,2.8943684331092254,-0.7580513366787757,-0.1619123131620609,3.8514472696790003,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,-0.1619123131620609,0.42266415546022,1.5892312826899408,1.9473741733456051,3.192469446149936,1.5557134250916398,1.522027904662708,3.6549956055948876,0.5412829355853829,2.3177928418789855,2.554155818031785,1.9155840365977252,2.976917059317765,-0.8063746087452964,3.679843814797915,0.38263514328382814,2.640766626646635,-0.07503752950409251,0.30182221516229196,2.041867375489916,0.1786609951774037,-0.11832544439901459,2.227038925427992,3.5799366048175845,1.7543699026919297,6.753408671655479,-0.25000179333226685,2.669400494336479,1.3855706609057188,-0.5219578544209845,1.2109881782657737,1.103996441331084,-0.7580513366787757,-1.0035370570387363,0.7722057037721174,1.3510176219205223	3367
Vacuolar lumen	30	65	4.946801749651868	7.544274164808546e-07	Q92820,P10253,O14773,Q9UM22,Q8IV08,Q9BTY2,P50897,P13473,Q14108,P07602,Q99536,P11117,Q99538,O00584,Q8NHP8,O00560,P54802,O00462,P06280,P16278,Q9NZJ7,P15586,P06865,Q13510,O00754,P04066,P61916,P10619,P17900,P07686	Localization	GO Cellular component	msigdb_gocc	139,143,20,21,151,153,29,30,32,34,164,37,177,53,55,188,65,66,67,68,222,85,84,90,208,94,99,106,107,119	66,188,53,208,20,2814,2241,210,94,67,84,2159,1057,34,119,2868,143,106,37,2712,2320,30,633,85,68,107,1479,2873,3247,1994,2876,2670,3013,29,2831,2336,869,2465,65,1745,2466,99,1146,2343,2404,1410,1497,90,32,1761,151,2355,55,139,1522,2623,164,177,153,1273,2217,2224,222,21,2228	2.5831453876103505,1.3162849902600815,2.782782542710472,1.2109881782657737,3.9953969719732,-0.7580513366787757,-0.33934491131952355,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,-0.29451413807445087,0.26103110464403734,3.297852942116772,1.8193146884450921,-0.8063746087452964,1.5892312826899408,1.9473741733456051,3.192469446149936,-0.6625285072121776,-0.38449929077288447,3.6549956055948876,0.5412829355853829,2.3177928418789855,2.554155818031785,1.9155840365977252,0.05307774962454346,-0.8063746087452964,-1.416440179685344,-0.2058028271615026,-0.8063746087452964,-0.6153160198205229,-0.9536627270282968,3.679843814797915,-0.7580513366787757,-0.38449929077288447,0.38263514328382814,-0.4758002447614249,2.640766626646635,-0.07503752950409251,-0.4758002447614249,2.041867375489916,0.2199786322467286,-0.38449929077288447,-0.42998258634220327,0.09521457913715693,0.05307774962454346,2.227038925427992,3.5799366048175845,-0.07503752950409251,1.5557134250916398,-0.38449929077288447,2.782782542710472,1.6225833456176855,0.05307774962454346,-0.5684611504154431,1.4541462370669627,1.3855706609057188,1.5557134250916398,0.1786609951774037,-0.29451413807445087,-0.29451413807445087,1.2109881782657737,3.9953969719732,-0.29451413807445087	3367
Azurophil granule	25	68	4.3404994000133215	1.421592568640051e-05	P42785,Q92820,O15260,P10253,Q9BTY2,P11279,P13473,P07602,Q99536,O00584,O00560,O00462,P06280,P16278,Q9NZJ7,Q92542,P15586,P06865,O00754,P04066,P61916,P10619,P17900,P27105,P07686	Localization	GO Cellular component	msigdb_gocc	2,139,14,143,153,150,30,34,164,53,188,66,67,68,222,218,85,84,208,94,99,106,107,114,119	66,188,53,208,14,1205,2814,2313,688,1382,2241,94,67,84,2159,1057,34,119,143,106,2320,150,30,633,85,68,107,1479,114,2873,3247,2721,2,3013,2831,3155,2598,2336,869,2465,1745,2466,99,1146,2343,2404,1410,225,1497,1761,876,821,2355,883,218,139,1433,1522,2623,164,2804,153,322,2217,2224,222,1708,2228	2.5831453876103505,1.3162849902600815,2.782782542710472,1.2109881782657737,4.34342738654226,0.1786609951774037,-0.7580513366787757,-0.38449929077288447,0.5019846818620551,0.09521457913715693,-0.33934491131952355,2.1041468018137355,2.554155818031785,2.3177928418789855,-0.29451413807445087,0.26103110464403734,3.297852942116772,1.8193146884450921,1.5892312826899408,1.9473741733456051,-0.38449929077288447,1.5557134250916398,3.6549956055948876,0.5412829355853829,2.3177928418789855,2.554155818031785,1.9155840365977252,0.05307774962454346,1.8515558846925475,-0.8063746087452964,-1.416440179685344,-0.6625285072121776,6.292167445838333,-0.9536627270282968,-0.7580513366787757,-1.1554855115344582,-0.5684611504154431,-0.38449929077288447,0.38263514328382814,-0.4758002447614249,-0.07503752950409251,-0.4758002447614249,2.041867375489916,0.2199786322467286,-0.38449929077288447,-0.42998258634220327,0.09521457913715693,1.1755156156311373,0.05307774962454346,-0.07503752950409251,0.38263514328382814,0.42266415546022,-0.38449929077288447,0.38263514328382814,1.2109881782657737,1.6225833456176855,0.09521457913715693,0.05307774962454346,-0.5684611504154431,1.4541462370669627,-0.7101048204413503,1.5557134250916398,0.9217383587835264,-0.29451413807445087,-0.29451413807445087,1.2109881782657737,-0.032043988936474706,-0.29451413807445087	3367
Corneal opacity	15	58	3.7450981896573214	0.0001803232365509	P06280,P16278,P10619,Q06136,Q16625,O43933,O43505,O75844,P34913,Q13510,O00754,O96028,Q9UBM7,P04066,Q03001	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	67,68,106,11,168,15,122,113,88,90,208,92,63,94,191	208,1202,908,122,1468,2058,1979,15,2863,1471,2448,2515,113,2156,690,92,1816,210,94,67,1306,106,68,797,483,88,2254,1006,936,333,1066,696,1568,394,1405,1571,191,11,2181,1924,90,747,3284,2347,2929,168,2019,1935,1084,970,2987,1537,2046,615,63,514,2858,302	1.2109881782657737,0.1786609951774037,0.342355682402477,1.7869199137107399,0.05307774962454346,-0.25000179333226685,-0.2058028271615026,4.320727255133443,-0.8063746087452964,0.05307774962454346,-0.4758002447614249,-0.5219578544209845,1.8515558846925475,-0.29451413807445087,0.5019846818620551,2.1658669221988482,-0.11832544439901459,1.2109881782657737,2.1041468018137355,2.554155818031785,0.13707430384263497,1.9473741733456051,2.554155818031785,0.42266415546022,0.657768615715268,2.2574227850195774,-0.33934491131952355,0.30182221516229196,0.342355682402477,0.884673610049861,0.26103110464403734,0.5019846818620551,0.010659648604851009,0.7722057037721174,0.09521457913715693,0.010659648604851009,1.3162849902600815,4.783524978682848,-0.29451413807445087,-0.1619123131620609,2.227038925427992,0.46244619964697814,-1.5776059098511652,-0.38449929077288447,-0.8550813717441338,1.419946185566603,-0.2058028271615026,-0.1619123131620609,0.26103110464403734,0.342355682402477,-0.9041772408267448,0.05307774962454346,-0.2058028271615026,0.580344223839915,2.669400494336479,0.657768615715268,-0.7580513366787757,0.9585953053509725	3367
Intrinsic component of plasma membrane	23	72	3.720179200810448	0.0001990814705532	Q8WTV0,P11279,Q99808,Q9NR28,P11717,O60637,P20645,P01889,Q15043,O15118,Q99805,Q9H0U3,O00560,O43657,P30825,P05067,Q92542,P16615,P41440,Q9UIQ6,P27105,Q99996,P02786	Localization	GO Cellular component	msigdb_gocc	5,150,158,291,156,35,44,294,315,46,184,322,188,71,201,83,218,211,102,103,114,116,239	989,1201,188,786,524,908,46,1715,71,1209,35,1056,1130,294,239,527,1215,83,1001,2064,1307,1556,150,156,1310,211,346,864,44,114,927,201,3046,635,1900,102,1139,807,740,2781,1069,1495,1324,1325,2789,2183,454,315,2737,1584,1341,548,659,1345,1028,5,218,2119,184,158,116,1099,1615,322,2569,291,511,103,1285,2376,1710,988	0.30182221516229196,0.1786609951774037,1.3162849902600815,0.42266415546022,0.619171741197861,0.342355682402477,2.8943684331092254,-0.07503752950409251,2.4958131623722344,0.1786609951774037,3.218961116049131,0.26103110464403734,0.2199786322467286,0.9585953053509725,1.103996441331084,0.619171741197861,0.1786609951774037,2.3477816274627044,0.30182221516229196,-0.25000179333226685,0.13707430384263497,0.010659648604851009,1.5557134250916398,1.522027904662708,0.13707430384263497,1.2109881782657737,0.8473984012280706,0.38263514328382814,2.976917059317765,1.8515558846925475,0.342355682402477,1.246272443990728,-1.0035370570387363,0.5412829355853829,-0.1619123131620609,2.0105143282367153,0.2199786322467286,0.42266415546022,0.46244619964697814,-0.7101048204413503,0.26103110464403734,0.05307774962454346,0.13707430384263497,0.13707430384263497,-0.7101048204413503,-0.29451413807445087,0.6961379107980552,0.9217383587835264,-0.6625285072121776,0.010659648604851009,0.13707430384263497,0.619171741197861,0.5412829355853829,0.13707430384263497,0.30182221516229196,5.895453047698817,1.2109881782657737,-0.25000179333226685,1.3510176219205223,1.522027904662708,1.8515558846925475,0.26103110464403734,0.010659648604851009,0.9217383587835264,-0.5219578544209845,0.995247055805408,0.657768615715268,2.0105143282367153,0.1786609951774037,-0.38449929077288447,-0.032043988936474706,0.342355682402477	3367
Lysosomal lumen	26	36	3.700296770114654	0.000215347481151	P10253,O14773,Q9UM22,Q8IV08,P50897,P13473,Q14108,P07602,P11117,Q99538,O00584,Q8NHP8,P54802,O00462,P06280,P16278,Q9NZJ7,P15586,P06865,Q13510,O00754,P04066,P61916,P10619,P17900,P07686	Localization	GO Cellular component	msigdb_gocc	143,20,21,151,29,30,32,34,37,177,53,55,65,66,67,68,222,85,84,90,208,94,99,106,107,119	66,53,208,20,2814,210,94,67,84,34,119,2868,143,106,37,2712,30,633,85,68,107,1994,2876,2670,29,65,99,90,32,151,2355,55,177,1273,222,21	2.5831453876103505,2.782782542710472,1.2109881782657737,3.9953969719732,-0.7580513366787757,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,-0.8063746087452964,1.5892312826899408,1.9473741733456051,3.192469446149936,-0.6625285072121776,3.6549956055948876,0.5412829355853829,2.3177928418789855,2.554155818031785,1.9155840365977252,-0.2058028271615026,-0.8063746087452964,-0.6153160198205229,3.679843814797915,2.640766626646635,2.041867375489916,2.227038925427992,3.5799366048175845,1.5557134250916398,-0.38449929077288447,2.782782542710472,1.3855706609057188,0.1786609951774037,1.2109881782657737,3.9953969719732	3367
Cellular lipid catabolic process	20	62	3.611454038607109	0.0003044850516513	Q8NCC3,P49748,Q8WTV0,Q99735,Q2T9J0,P50897,O15254,O95470,Q13011,Q8NHP8,Q8IY17,P06280,P28288,Q9BWD1,P06865,Q13510,P04062,P04066,P17900,P07686	Processes and pathways	GO Biological process	msigdb_gobp	0,130,5,273,157,29,155,160,176,55,316,67,197,77,84,90,210,94,107,119	303,2763,2235,2510,155,1639,2649,3329,160,1554,210,94,2910,1984,67,84,119,2160,3336,2660,107,1390,3121,2390,1733,2250,197,3247,1651,1824,532,2331,932,1222,2593,130,579,29,1996,2400,1410,176,90,1926,750,1156,2276,157,1250,316,659,403,0,55,5,1519,2210,273,77,3139,561,564	0.9217383587835264,-0.7101048204413503,-0.33934491131952355,-0.5219578544209845,1.522027904662708,-0.032043988936474706,-0.6153160198205229,-1.9669363010637892,1.4881728202808266,0.010659648604851009,1.2109881782657737,2.1041468018137355,-0.8550813717441338,-0.2058028271615026,2.554155818031785,2.3177928418789855,1.8193146884450921,-0.29451413807445087,-2.1394401565148997,-0.6153160198205229,1.9155840365977252,0.09521457913715693,-1.1044492003404638,-0.42998258634220327,-0.07503752950409251,-0.33934491131952355,1.2813706494606423,-1.416440179685344,-0.032043988936474706,-0.11832544439901459,0.619171741197861,-0.38449929077288447,0.342355682402477,0.1786609951774037,-0.5684611504154431,1.6887973998936312,0.580344223839915,3.679843814797915,-0.2058028271615026,-0.42998258634220327,0.09521457913715693,1.3855706609057188,2.227038925427992,-0.1619123131620609,0.46244619964697814,0.2199786322467286,-0.33934491131952355,1.522027904662708,0.1786609951774037,0.9217383587835264,0.5412829355853829,0.7722057037721174,6.753408671655479,2.782782542710472,5.895453047698817,0.05307774962454346,-0.29451413807445087,1.031696165695717,2.4369781355796594,-1.1044492003404638,0.619171741197861,0.619171741197861	3367
Predicted secreted proteins	19	48	3.6093854742333953	0.0003069232405052	Q8WUJ1,P80303,Q9NZ08,Q9HB40,Q9UM22,Q9BTY2,P81605,Q9Y4P3,O00584,Q08380,Q9P2K2,Q9BUR5,Q9UMX5,P05067,O60888,Q02818,P61916,Q08431,P02786	Functions	Protein Atlas Protein class	protein_atlas_protein_class	4,10,148,16,21,153,286,302,53,69,206,203,78,83,91,93,99,243,239	53,786,1642,91,1646,574,239,2316,83,3004,2159,2958,1386,1647,2068,3120,3086,3087,929,2828,2335,1400,642,99,10,286,93,1659,69,243,2971,2183,295,3313,4,665,3219,153,203,1615,1954,1703,16,148,206,21,78,302	2.782782542710472,0.42266415546022,-0.032043988936474706,2.1965207527852213,-0.032043988936474706,0.580344223839915,1.103996441331084,-0.38449929077288447,2.3477816274627044,-0.9536627270282968,-0.29451413807445087,-0.9041772408267448,0.09521457913715693,-0.032043988936474706,-0.25000179333226685,-1.1044492003404638,-1.053799466605388,-1.053799466605388,0.342355682402477,-0.7580513366787757,-0.38449929077288447,0.09521457913715693,0.5412829355853829,2.041867375489916,4.783524978682848,0.995247055805408,2.1658669221988482,-0.032043988936474706,2.554155818031785,1.103996441331084,-0.9041772408267448,-0.29451413807445087,0.9585953053509725,-1.7978135821100152,6.042035212995324,0.5412829355853829,-1.3109065691871442,1.5557134250916398,1.246272443990728,0.010659648604851009,-0.1619123131620609,-0.032043988936474706,4.320727255133443,1.5892312826899408,1.246272443990728,3.9953969719732,2.4369781355796594,0.9585953053509725	3367
Lipid localization	20	76	3.488491403373279	0.000485754441323	Q8WTV0,P08183,O15260,Q9H4L5,Q9H6V9,Q9BQE5,Q14108,P07602,Q99720,O43772,Q14849,P35790,O15118,Q9BZF1,P28288,Q9BUR5,Q9NZJ7,P61916,P17900,P07686	Processes and pathways	GO Biological process	msigdb_gobp	5,132,14,147,19,27,32,34,36,42,49,48,46,192,197,203,222,99,107,119	989,2763,2510,46,14,42,1639,2864,2817,1381,1129,330,2956,1982,210,2316,2159,34,119,1985,132,1556,1647,107,924,3121,2390,197,575,1061,1824,530,532,48,2922,579,99,2089,2007,1410,2786,1324,1496,32,1151,49,1419,821,1250,2115,3313,2977,5,2897,889,839,36,27,2625,203,2133,192,2899,2215,147,19,2044,222,1708,279,1455,902,1964,3322,3296,1375	0.30182221516229196,-0.7101048204413503,-0.5219578544209845,2.8943684331092254,4.34342738654226,3.0585160335120065,-0.032043988936474706,-0.8063746087452964,-0.7580513366787757,0.09521457913715693,0.2199786322467286,0.884673610049861,-0.9041772408267448,-0.2058028271615026,1.2109881782657737,-0.38449929077288447,-0.29451413807445087,3.297852942116772,1.8193146884450921,-0.2058028271615026,1.6557714498436458,0.010659648604851009,-0.032043988936474706,1.9155840365977252,0.342355682402477,-1.1044492003404638,-0.42998258634220327,1.2813706494606423,0.580344223839915,0.26103110464403734,-0.11832544439901459,0.619171741197861,0.619171741197861,2.8943684331092254,-0.8550813717441338,0.580344223839915,2.041867375489916,-0.25000179333226685,-0.2058028271615026,0.09521457913715693,-0.7101048204413503,0.13707430384263497,0.05307774962454346,3.5799366048175845,0.2199786322467286,2.8943684331092254,0.09521457913715693,0.42266415546022,0.1786609951774037,-0.25000179333226685,-1.7978135821100152,-0.9041772408267448,5.895453047698817,-0.8063746087452964,0.38263514328382814,0.42266415546022,3.218961116049131,3.7292869846617753,-0.5684611504154431,1.246272443990728,-0.25000179333226685,1.3162849902600815,-0.8063746087452964,-0.29451413807445087,1.5892312826899408,4.042759805139087,-0.2058028271615026,1.2109881782657737,-0.032043988936474706,1.031696165695717,0.09521457913715693,0.38263514328382814,-0.1619123131620609,-1.853811091154964,-1.632089162713181,0.13707430384263497	3367
Regulation of lipid metabolic process	13	53	3.479405243165905	0.0005025280489971	Q92604,P49748,P07602,P61916,Q8WTV0,Q96N66,Q96G23,O75844,Q9NZJ7,P34913,Q13510,Q2T9J0,Q9UBM7	Processes and pathways	GO Biological process	msigdb_gobp	259,130,34,99,5,133,38,113,222,88,90,157,63	2763,2152,2704,1981,113,3329,2315,1129,1554,2316,1215,34,2767,694,1730,1061,1824,88,637,448,130,579,2834,2000,99,451,2785,1410,1496,90,1073,1663,1332,253,749,157,1419,821,883,2202,5,259,2897,38,133,975,2750,222,63,2144,1963,1964,3270	-0.7101048204413503,-0.29451413807445087,-0.6625285072121776,-0.2058028271615026,1.8515558846925475,-1.9669363010637892,-0.38449929077288447,0.2199786322467286,0.010659648604851009,-0.38449929077288447,0.1786609951774037,3.297852942116772,-0.7101048204413503,0.5019846818620551,-0.07503752950409251,0.26103110464403734,-0.11832544439901459,2.2574227850195774,0.5412829355853829,0.6961379107980552,1.6887973998936312,0.580344223839915,-0.7580513366787757,-0.2058028271615026,2.041867375489916,0.6961379107980552,-0.7101048204413503,0.09521457913715693,0.05307774962454346,2.227038925427992,0.26103110464403734,-0.032043988936474706,0.13707430384263497,1.0679451413858796,0.46244619964697814,1.522027904662708,0.09521457913715693,0.42266415546022,0.38263514328382814,-0.29451413807445087,5.895453047698817,1.0679451413858796,-0.8063746087452964,3.192469446149936,1.6557714498436458,0.342355682402477,-0.6625285072121776,1.2109881782657737,2.669400494336479,-0.25000179333226685,-0.1619123131620609,-0.1619123131620609,-1.4697807385854578	3367
Anion transport	18	59	3.395346924991953	0.0006854168944523	Q9H2D1,P07602,P21796,O60831,P28288,P08183,P41440,Q9UHG3,P80404,Q9UBX3,P30825,Q15043,Q9NZJ7,P45880,Q9C0H2,Q8TB61,Q9HC21,Q99808	Processes and pathways	GO Biological process	msigdb_gobp	123,34,309,362,197,132,102,74,75,142,201,315,222,115,56,270,360,158	2305,1889,2814,1639,362,630,2450,1304,2316,1001,2064,34,132,2384,3338,1556,1310,419,1647,309,197,1061,201,102,115,641,1141,807,1909,2781,75,1069,1495,1496,1758,2188,2346,315,1584,594,2019,1250,270,158,56,1530,123,2218,1872,360,2852,222,142,74,2300,1285,1372,2230,1376	-0.38449929077288447,-0.1619123131620609,-0.7580513366787757,-0.032043988936474706,0.8099100211162025,0.5412829355853829,-0.4758002447614249,0.13707430384263497,-0.38449929077288447,0.30182221516229196,-0.25000179333226685,3.297852942116772,1.6557714498436458,-0.42998258634220327,-2.197689911987167,0.010659648604851009,0.13707430384263497,0.7342826270023676,-0.032043988936474706,0.9217383587835264,1.2813706494606423,0.26103110464403734,1.246272443990728,2.0105143282367153,1.8515558846925475,0.5412829355853829,0.2199786322467286,0.42266415546022,-0.1619123131620609,-0.7101048204413503,2.4369781355796594,0.26103110464403734,0.05307774962454346,0.05307774962454346,-0.07503752950409251,-0.29451413807445087,-0.38449929077288447,0.9217383587835264,0.010659648604851009,0.580344223839915,-0.2058028271615026,0.1786609951774037,1.031696165695717,1.522027904662708,2.782782542710472,0.05307774962454346,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,-0.7580513366787757,1.2109881782657737,1.6225833456176855,2.46645778006456,-0.33934491131952355,0.1786609951774037,0.13707430384263497,-0.29451413807445087,0.13707430384263497	3367
Membrane lipid metabolic process	19	35	3.3889574771897166	0.000701588894741	Q8NCC3,Q99735,Q06136,P50897,O95470,P07602,Q96G23,Q99805,P06280,P16278,Q9NZJ7,P06865,Q13510,P04062,P04066,Q8NBX0,Q9H490,P17900,P07686	Processes and pathways	GO Biological process	msigdb_gobp	0,273,11,29,160,34,38,184,67,68,222,84,90,210,94,230,235,107,119	282,1204,1812,160,210,94,67,84,34,119,68,107,924,1899,2251,29,1410,11,1496,90,1335,230,0,1601,718,38,380,273,184,235,561,471,222,851,1708	0.995247055805408,0.1786609951774037,-0.11832544439901459,1.4881728202808266,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,2.554155818031785,1.9155840365977252,0.342355682402477,-0.1619123131620609,-0.33934491131952355,3.679843814797915,0.09521457913715693,4.783524978682848,0.05307774962454346,2.227038925427992,0.13707430384263497,1.1755156156311373,6.753408671655479,0.010659648604851009,0.5019846818620551,3.192469446149936,0.8099100211162025,1.031696165695717,1.3510176219205223,1.1398524773123389,0.619171741197861,0.6961379107980552,1.2109881782657737,0.42266415546022,-0.032043988936474706	3367
Vacuole organization	13	54	3.3854939198845724	0.0007105028350546	Q86VS8,Q14108,P54802,P11117,P10253,O14773,P07686,O75503,P04062,P53365,P16615,P50897,Q12768	Processes and pathways	GO Biological process	msigdb_gobp	161,32,65,37,143,20,119,24,210,181,211,29,127	1713,20,2648,24,1553,2584,3203,210,2159,119,143,37,211,2388,448,1228,29,1907,181,65,3283,2001,2263,127,32,2346,1929,335,821,161,2115,257,2202,1685,1349,889,1353,1608,2212,1104,2040,846,1043,2298,2044,2575,2049,2858,3322,3144,1629,3145,2994,2052	-0.07503752950409251,3.9953969719732,-0.6153160198205229,3.8514472696790003,0.010659648604851009,-0.5684611504154431,-1.3109065691871442,1.2109881782657737,-0.29451413807445087,1.8193146884450921,1.5892312826899408,3.192469446149936,1.2109881782657737,-0.42998258634220327,0.6961379107980552,0.1786609951774037,3.679843814797915,-0.1619123131620609,1.3510176219205223,2.640766626646635,-1.5776059098511652,-0.2058028271615026,-0.33934491131952355,1.7216629695769743,3.5799366048175845,-0.38449929077288447,-0.1619123131620609,0.884673610049861,0.42266415546022,1.4881728202808266,-0.25000179333226685,1.0679451413858796,-0.29451413807445087,-0.032043988936474706,0.13707430384263497,0.38263514328382814,0.13707430384263497,0.010659648604851009,-0.29451413807445087,0.26103110464403734,-0.2058028271615026,0.42266415546022,0.30182221516229196,-0.33934491131952355,-0.2058028271615026,-0.5219578544209845,-0.2058028271615026,-0.7580513366787757,-1.853811091154964,-1.1044492003404638,0.010659648604851009,-1.1044492003404638,-0.9041772408267448,-0.2058028271615026	3367
Protein localization	31	69	3.34482199720024	0.0008233539426896	Q9NR77,O43933,O15228,O14925,Q13505,Q9NS69,Q9UJ83,P56589,Q2T9J0,O15254,Q10713,P09601,P08574,P12236,Q13011,Q99595,P46379,Q5JRX3,O96008,P21796,P28288,Q9Y5L4,P51648,P05067,O75431,P34913,P50402,O60830,Q13190,Q9Y512,P60059	Processes and pathways	Reactome Pathways	msigdb_reactome	278,15,624,623,18,26,564,394,157,155,287,40,529,419,176,178,54,542,308,309,197,223,333,83,443,88,578,96,585,521,241	1200,2235,623,2510,624,155,996,2814,2150,1639,15,96,2448,3000,443,1813,2649,630,3329,1719,1554,308,83,1896,529,2160,40,2161,1310,419,2068,309,3121,1989,197,88,2330,2666,54,578,333,1996,394,241,1747,287,176,585,18,1926,157,1077,542,2021,1167,971,178,1864,847,278,26,1877,1708,564,1285,854,1120,521,223	0.1786609951774037,-0.33934491131952355,0.5412829355853829,-0.5219578544209845,0.5412829355853829,1.522027904662708,0.30182221516229196,-0.7580513366787757,-0.29451413807445087,-0.032043988936474706,4.320727255133443,2.0730777150539357,-0.4758002447614249,-0.9536627270282968,0.6961379107980552,-0.11832544439901459,-0.6153160198205229,0.5412829355853829,-1.9669363010637892,-0.07503752950409251,0.010659648604851009,0.9217383587835264,2.3477816274627044,-0.1619123131620609,0.619171741197861,-0.29451413807445087,3.1123997852653797,-0.29451413807445087,0.13707430384263497,0.7342826270023676,-0.25000179333226685,0.9217383587835264,-1.1044492003404638,-0.2058028271615026,1.2813706494606423,2.2574227850195774,-0.38449929077288447,-0.6153160198205229,2.782782542710472,0.580344223839915,0.884673610049861,-0.2058028271615026,0.7722057037721174,1.103996441331084,-0.07503752950409251,0.995247055805408,1.3855706609057188,0.580344223839915,4.183049042361933,-0.1619123131620609,1.522027904662708,0.26103110464403734,0.619171741197861,-0.2058028271615026,0.2199786322467286,0.342355682402477,1.3855706609057188,-0.11832544439901459,0.42266415546022,1.031696165695717,3.802828202328214,-0.11832544439901459,-0.032043988936474706,0.619171741197861,0.1786609951774037,0.42266415546022,0.26103110464403734,0.657768615715268,1.2109881782657737	3367
Secretory granule membrane	17	63	3.317030893880472	0.0009097955576387	P42785,P07602,O00462,Q07065,Q9Y2Q5,O15260,P01889,Q9NZJ7,P10253,P30519,Q92542,P27105,P13473,Q93050,Q08431,P11279,P11717	Localization	GO Cellular component	msigdb_gocc	2,34,66,225,281,14,294,222,143,51,218,114,30,62,243,150,156	1201,66,2510,14,2151,2513,2313,688,1645,631,1382,294,34,143,1307,150,156,30,2247,3120,2714,114,51,3248,3047,635,2721,2,1224,1010,2598,1907,2399,2543,2001,1230,1832,1833,487,225,243,2788,2271,1329,369,817,953,821,3133,883,1028,218,62,1433,2804,2568,322,2043,222,1708,2300,281,2995	0.1786609951774037,2.5831453876103505,-0.5219578544209845,4.34342738654226,-0.29451413807445087,-0.5219578544209845,-0.38449929077288447,0.5019846818620551,-0.032043988936474706,0.5412829355853829,0.09521457913715693,0.9585953053509725,3.297852942116772,1.5892312826899408,0.13707430384263497,1.5557134250916398,1.522027904662708,3.6549956055948876,-0.33934491131952355,-1.1044492003404638,-0.6625285072121776,1.8515558846925475,2.838795997863869,-1.416440179685344,-1.0035370570387363,0.5412829355853829,-0.6625285072121776,6.292167445838333,0.1786609951774037,0.30182221516229196,-0.5684611504154431,-0.1619123131620609,-0.42998258634220327,-0.5219578544209845,-0.2058028271615026,0.1786609951774037,-0.11832544439901459,-0.11832544439901459,0.657768615715268,1.1755156156311373,1.103996441331084,-0.7101048204413503,-0.33934491131952355,0.13707430384263497,0.8099100211162025,0.42266415546022,0.342355682402477,0.42266415546022,-1.1044492003404638,0.38263514328382814,0.30182221516229196,1.2109881782657737,2.669400494336479,0.09521457913715693,-0.7101048204413503,-0.5219578544209845,0.9217383587835264,-0.2058028271615026,1.2109881782657737,-0.032043988936474706,-0.33934491131952355,1.031696165695717,-0.9041772408267448	3367
Intrinsic component of endoplasmic reticulum membrane	26	48	3.110808013649881	0.001865761998377	P57088,Q9BUN8,Q86UP2,Q12981,Q86XL3,Q96A33,Q8TB61,Q9Y282,O95470,Q9Y4P3,P04439,Q9P035,P01889,Q969N2,Q9HCU5,Q15629,Q9UBM7,Q9NZ01,Q9NXW2,Q9NQC3,Q8TCT9,Q15125,Q9H490,Q96S52,O75844,O76024	Localization	GO Cellular component	msigdb_gocc	742,407,548,746,269,831,270,25,160,302,527,851,294,718,467,60,63,471,204,221,354,589,235,380,113,364	989,992,2510,1295,113,364,160,294,527,1307,2774,927,1652,1139,742,871,746,1762,1076,2188,589,60,1336,2106,548,269,1776,1597,270,354,1601,718,831,380,841,2625,407,235,467,221,204,471,851,1282,63,25,302,1375	0.30182221516229196,0.30182221516229196,-0.5219578544209845,0.13707430384263497,1.8515558846925475,0.8099100211162025,1.4881728202808266,0.9585953053509725,0.619171741197861,0.13707430384263497,-0.7101048204413503,0.342355682402477,-0.032043988936474706,0.2199786322467286,0.46244619964697814,0.38263514328382814,0.46244619964697814,-0.07503752950409251,0.26103110464403734,-0.29451413807445087,0.580344223839915,2.6979179668449453,0.13707430384263497,-0.25000179333226685,0.619171741197861,1.031696165695717,-0.07503752950409251,0.010659648604851009,1.031696165695717,0.8473984012280706,0.010659648604851009,0.5019846818620551,0.42266415546022,0.8099100211162025,0.42266415546022,-0.5684611504154431,0.7722057037721174,1.1398524773123389,0.6961379107980552,1.2109881782657737,1.246272443990728,0.6961379107980552,0.42266415546022,0.1786609951774037,2.669400494336479,3.8271781683887824,0.9585953053509725,0.13707430384263497	3367
Lipid catabolic process	21	77	3.0596097312685537	0.0022162558279195	Q8NCC3,P49748,Q8WTV0,Q99735,Q9H6V9,Q2T9J0,P50897,O15254,O95470,Q13011,Q8NHP8,Q8IY17,P06280,P28288,Q9BWD1,P06865,Q13510,P04062,P04066,P17900,P07686	Processes and pathways	GO Biological process	msigdb_gobp	0,130,5,273,19,157,29,155,160,176,55,316,67,197,77,84,90,210,94,107,119	303,2763,2235,2510,155,1639,2649,3329,160,1554,210,94,2910,1984,67,84,119,2160,3336,2767,2660,107,1390,3121,2390,1733,2250,197,3247,1651,1824,532,2331,2876,932,1222,2593,1485,130,579,29,1907,1996,2400,2838,1409,1410,176,1496,90,3266,1926,1845,750,1156,2276,157,1586,1250,316,713,659,403,464,0,55,5,1519,2128,2210,273,77,1529,19,3139,561,564	0.9217383587835264,-0.7101048204413503,-0.33934491131952355,-0.5219578544209845,1.522027904662708,-0.032043988936474706,-0.6153160198205229,-1.9669363010637892,1.4881728202808266,0.010659648604851009,1.2109881782657737,2.1041468018137355,-0.8550813717441338,-0.2058028271615026,2.554155818031785,2.3177928418789855,1.8193146884450921,-0.29451413807445087,-2.1394401565148997,-0.7101048204413503,-0.6153160198205229,1.9155840365977252,0.09521457913715693,-1.1044492003404638,-0.42998258634220327,-0.07503752950409251,-0.33934491131952355,1.2813706494606423,-1.416440179685344,-0.032043988936474706,-0.11832544439901459,0.619171741197861,-0.38449929077288447,-0.8063746087452964,0.342355682402477,0.1786609951774037,-0.5684611504154431,0.05307774962454346,1.6887973998936312,0.580344223839915,3.679843814797915,-0.1619123131620609,-0.2058028271615026,-0.42998258634220327,-0.7580513366787757,0.09521457913715693,0.09521457913715693,1.3855706609057188,0.05307774962454346,2.227038925427992,-1.4697807385854578,-0.1619123131620609,-0.11832544439901459,0.46244619964697814,0.2199786322467286,-0.33934491131952355,1.522027904662708,0.010659648604851009,0.1786609951774037,0.9217383587835264,0.5019846818620551,0.5412829355853829,0.7722057037721174,0.6961379107980552,6.753408671655479,2.782782542710472,5.895453047698817,0.05307774962454346,-0.25000179333226685,-0.29451413807445087,1.031696165695717,2.4369781355796594,0.05307774962454346,4.042759805139087,-1.1044492003404638,0.619171741197861,0.619171741197861	3367
Sphingolipid metabolic process	15	27	3.057659937785296	0.0022307256491387	Q8NCC3,O95470,P07602,P06280,P16278,Q96G23,Q06136,P17900,Q9NZJ7,Q99805,P07686,P06865,P04062,Q13510,P50897	Processes and pathways	GO Biological process	msigdb_gobp	0,160,34,67,68,38,11,107,222,184,119,84,210,90,29	282,1204,160,210,67,84,34,119,68,107,924,1899,2251,29,1410,11,1496,90,1335,0,38,184,561,471,222,851,1708	0.995247055805408,0.1786609951774037,1.4881728202808266,1.2109881782657737,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,2.554155818031785,1.9155840365977252,0.342355682402477,-0.1619123131620609,-0.33934491131952355,3.679843814797915,0.09521457913715693,4.783524978682848,0.05307774962454346,2.227038925427992,0.13707430384263497,6.753408671655479,3.192469446149936,1.3510176219205223,0.619171741197861,0.6961379107980552,1.2109881782657737,0.42266415546022,-0.032043988936474706	3367
transporter	29	57	3.055082771738963	0.0022499841712375	P49790,P61619,P55735,Q9NR77,P35658,O15397,Q99808,P57740,O75694,O43772,Q99595,Q99805,O60684,Q567V2,O15321,P53985,P52948,Q6N075,Q8TEX9,Q9C0E2,Q99567,O60830,Q96P70,P41440,Q12769,Q8N1F7,O00410,Q9H2D1,Q9HD45	Functions	Panther Protein class	panther_protein_class	739,871,870,278,636,626,158,646,526,42,178,184,791,72,685,807,806,594,355,358,765,96,502,102,584,882,477,123,124	477,1053,1465,1637,685,626,996,2814,42,791,96,526,1725,636,2395,102,2922,739,1566,938,806,1141,807,1909,1656,870,646,871,2089,584,1665,1927,72,594,1589,882,1170,1425,355,968,1031,1523,502,765,178,184,158,3278,358,123,1110,124,278,1625,2048,1964,1804	0.657768615715268,0.26103110464403734,0.05307774962454346,-0.032043988936474706,0.5019846818620551,0.5412829355853829,0.30182221516229196,-0.7580513366787757,3.0585160335120065,0.42266415546022,2.0730777150539357,0.619171741197861,-0.07503752950409251,0.5412829355853829,-0.42998258634220327,2.0105143282367153,-0.8550813717441338,0.46244619964697814,0.010659648604851009,0.342355682402477,0.42266415546022,0.2199786322467286,0.42266415546022,-0.1619123131620609,-0.032043988936474706,0.38263514328382814,0.5412829355853829,0.38263514328382814,-0.25000179333226685,0.580344223839915,-0.032043988936474706,-0.1619123131620609,2.4958131623722344,0.580344223839915,0.010659648604851009,0.38263514328382814,0.2199786322467286,0.09521457913715693,0.8473984012280706,0.342355682402477,0.30182221516229196,0.05307774962454346,0.657768615715268,0.46244619964697814,1.3855706609057188,1.3510176219205223,1.522027904662708,-1.523502876429464,0.8473984012280706,1.7869199137107399,0.26103110464403734,1.7869199137107399,1.031696165695717,0.010659648604851009,-0.2058028271615026,-0.1619123131620609,-0.07503752950409251	3367
Receptor	14	35	3.033326822929852	0.0024187349196114	Q14108,Q9NS69,Q9Y2I1,Q8WTV0,Q99720,P20645,Q14739,P30825,P24390,O15118,P55899,Q5KU26,P11279,P11717	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	32,26,135,5,36,44,76,201,47,46,86,120,150,156	1201,786,524,46,1808,239,2064,2867,1474,2523,2766,150,156,2068,44,47,201,635,86,1324,2183,32,747,76,1584,120,5,972,2750,36,26,135,567,1196,1198	0.1786609951774037,0.42266415546022,0.619171741197861,2.8943684331092254,-0.11832544439901459,1.103996441331084,-0.25000179333226685,-0.8063746087452964,0.05307774962454346,-0.5219578544209845,-0.7101048204413503,1.5557134250916398,1.522027904662708,-0.25000179333226685,2.976917059317765,2.8943684331092254,1.246272443990728,0.5412829355853829,2.3177928418789855,0.13707430384263497,-0.29451413807445087,3.5799366048175845,0.46244619964697814,2.4369781355796594,0.010659648604851009,1.8193146884450921,5.895453047698817,0.342355682402477,-0.6625285072121776,3.218961116049131,3.802828202328214,1.6557714498436458,0.619171741197861,0.2199786322467286,0.2199786322467286	3367
Steroid metabolic process	18	71	3.02501493499537	0.0024862085004269	O95470,P49748,P61916,Q8WTV0,P28288,Q15800,Q14739,Q14849,Q9H4L5,Q99538,O15118,P05067,P34913,Q13510,Q9BQE5,Q15392,Q16850,Q9UBM7	Processes and pathways	GO Biological process	msigdb_gobp	160,130,99,5,197,105,76,49,147,177,46,83,88,90,27,28,95,63	2235,2510,46,2315,160,2241,210,1215,83,2160,2818,3043,3085,694,924,3121,2872,1733,197,1061,88,532,367,1994,2876,2593,935,130,1829,1996,2336,2727,1401,99,2007,3355,2406,1409,1496,90,2927,1151,76,49,3266,589,3214,28,749,398,2098,105,95,651,821,464,5,2897,839,177,2210,27,1529,2215,1040,147,63,1455,1963,2300,3270	-0.33934491131952355,-0.5219578544209845,2.8943684331092254,-0.38449929077288447,1.4881728202808266,-0.33934491131952355,1.2109881782657737,0.1786609951774037,2.3477816274627044,-0.29451413807445087,-0.7580513366787757,-1.0035370570387363,-1.053799466605388,0.5019846818620551,0.342355682402477,-1.1044492003404638,-0.8063746087452964,-0.07503752950409251,1.2813706494606423,0.26103110464403734,2.2574227850195774,0.619171741197861,0.8099100211162025,-0.2058028271615026,-0.8063746087452964,-0.5684611504154431,0.342355682402477,1.6887973998936312,-0.11832544439901459,-0.2058028271615026,-0.38449929077288447,-0.6625285072121776,0.09521457913715693,2.041867375489916,-0.2058028271615026,-2.800617632892994,-0.42998258634220327,0.09521457913715693,0.05307774962454346,2.227038925427992,-0.8550813717441338,0.2199786322467286,2.4369781355796594,2.8943684331092254,-1.4697807385854578,0.580344223839915,-1.3109065691871442,3.7046073923024947,0.46244619964697814,0.7722057037721174,-0.25000179333226685,1.9790170949571289,2.1041468018137355,0.5412829355853829,0.42266415546022,0.6961379107980552,5.895453047698817,-0.8063746087452964,0.42266415546022,1.3855706609057188,-0.29451413807445087,3.7292869846617753,0.05307774962454346,-0.29451413807445087,0.30182221516229196,1.5892312826899408,2.669400494336479,0.09521457913715693,-0.1619123131620609,-0.33934491131952355,-1.4697807385854578	3367
Circulatory system process	16	70	3.0237361798313924	0.0024967406011155	P42785,P41440,P08183,P09601,Q9UIQ6,P80404,P42892,Q16625,Q9NZ08,Q9HB40,P30825,O75844,P10253,Q99996,P16615,Q99808	Processes and pathways	GO Biological process	msigdb_gobp	2,102,132,40,103,75,12,168,148,16,201,113,143,116,211,158	1635,570,1889,1642,415,526,113,3168,3001,574,2241,239,3003,528,1215,132,40,143,1556,2959,3042,2527,2247,211,864,1559,2716,3248,201,102,1738,448,2,12,1904,2075,803,2077,1829,807,2781,2000,3093,2606,75,489,538,1324,1922,2181,702,2184,706,1664,1245,1584,168,1250,373,2023,2203,1607,158,116,2937,16,982,148,103,2646	-0.032043988936474706,0.580344223839915,-0.1619123131620609,-0.032043988936474706,0.7342826270023676,0.619171741197861,1.8515558846925475,-1.206907661975204,-0.9536627270282968,0.580344223839915,-0.33934491131952355,1.103996441331084,-0.9536627270282968,0.619171741197861,0.1786609951774037,1.6557714498436458,3.1123997852653797,1.5892312826899408,0.010659648604851009,-0.9041772408267448,-1.0035370570387363,-0.5219578544209845,-0.33934491131952355,1.2109881782657737,0.38263514328382814,0.010659648604851009,-0.6625285072121776,-1.416440179685344,1.246272443990728,2.0105143282367153,-0.07503752950409251,0.6961379107980552,6.292167445838333,4.697545811150349,-0.1619123131620609,-0.25000179333226685,0.42266415546022,-0.25000179333226685,-0.11832544439901459,0.42266415546022,-0.7101048204413503,-0.2058028271615026,-1.053799466605388,-0.5684611504154431,2.4369781355796594,0.657768615715268,0.619171741197861,0.13707430384263497,-0.1619123131620609,-0.29451413807445087,0.5019846818620551,-0.29451413807445087,0.5019846818620551,-0.032043988936474706,0.1786609951774037,0.010659648604851009,1.419946185566603,0.1786609951774037,0.8099100211162025,-0.2058028271615026,-0.29451413807445087,0.010659648604851009,1.522027904662708,1.8515558846925475,-0.8550813717441338,4.320727255133443,0.342355682402477,1.5892312826899408,2.0105143282367153,-0.5684611504154431	3367
Glycosphingolipid metabolic process	6	9	3.016182595901115	0.0025597905985634	P06280,P16278,P17900,Q99805,P07686,P06865	Processes and pathways	GO Biological process	msigdb_gobp	67,68,107,184,119,84	210,67,84,119,68,107,1410,1496,184	1.2109881782657737,2.554155818031785,2.3177928418789855,1.8193146884450921,2.554155818031785,1.9155840365977252,0.09521457913715693,0.05307774962454346,1.3510176219205223	3367
SLC superfamily of solute carriers	15	38	3.0119981268336344	0.0025953419902149	Q9H2D1,P41440,Q6NT16,Q8IXU6,Q9Y6C9,O43772,Q70HW3,Q9UBX3,P30825,Q9BSK2,Q15043,Q9NZJ7,Q9H0U3,Q8TB61,Q99808	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	123,102,7,8,167,42,13,142,201,274,315,222,322,270,158	2510,42,1639,630,690,1304,1001,2384,1556,1310,419,201,102,1141,807,2781,1069,1495,315,1584,594,7,2019,1250,13,8,270,158,274,322,123,2218,1872,360,222,142,1285,167	-0.5219578544209845,3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.5019846818620551,0.13707430384263497,0.30182221516229196,-0.42998258634220327,0.010659648604851009,0.13707430384263497,0.7342826270023676,1.246272443990728,2.0105143282367153,0.2199786322467286,0.42266415546022,-0.7101048204413503,0.26103110464403734,0.05307774962454346,0.9217383587835264,0.010659648604851009,0.580344223839915,4.910685979818012,-0.2058028271615026,0.1786609951774037,4.433541950109594,4.889640280593516,1.031696165695717,1.522027904662708,1.031696165695717,0.9217383587835264,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627	3367
Intrinsic component of organelle membrane	56	111	2.9881320160566607	0.0028068828274081	P57088,L0R6Q1,Q9BUN8,Q9UH99,P42892,Q16134,Q86UP2,O14925,Q12981,Q16891,Q13505,Q86XL3,Q96A33,Q9Y282,Q8TB61,P56589,P13473,O95470,Q9Y4P3,P04439,Q9P035,P01889,O15118,Q99595,Q969N2,Q9HCU5,Q9NVH1,Q15629,Q9UBM7,O96008,Q9NZ01,Q10471,Q9NXW2,Q14739,Q9BUR5,O95070,Q9NQC3,O75431,Q9HC21,Q9UG56,P50416,Q8TCT9,O60830,Q6ZRP7,Q15125,Q9H490,Q9Y2R0,Q96S52,Q9Y512,O75844,Q8WVX9,O76024,O75880,O43752,O43505,Q9BPX6	Localization	GO Cellular component	msigdb_gocc	742,251,407,280,12,750,548,623,746,650,18,269,831,25,270,394,30,160,302,527,851,294,46,178,718,467,726,60,63,308,471,312,204,76,203,689,221,443,360,361,579,354,96,227,589,235,110,380,521,113,758,364,481,733,122,668	989,251,992,623,2510,46,1378,1295,122,733,1639,858,96,443,113,481,364,1719,1894,689,160,1304,308,294,527,1307,1310,30,864,2388,2774,927,1652,2666,12,579,1907,1139,394,742,871,1069,312,746,18,1762,76,1076,2188,1927,589,1929,60,750,650,1335,1336,1506,1509,2106,1339,227,548,269,2115,1776,1085,1856,880,1597,1683,270,354,758,1601,718,831,380,841,178,668,2625,1441,407,203,1950,1871,235,1872,2368,360,467,221,2631,726,1877,204,471,851,1282,63,361,1284,280,25,110,3080,302,1289,521,1375	0.30182221516229196,1.0679451413858796,0.30182221516229196,0.5412829355853829,-0.5219578544209845,2.8943684331092254,0.09521457913715693,0.13707430384263497,1.7869199137107399,0.46244619964697814,-0.032043988936474706,0.38263514328382814,2.0730777150539357,0.6961379107980552,1.8515558846925475,0.657768615715268,0.8099100211162025,-0.07503752950409251,-0.1619123131620609,0.5019846818620551,1.4881728202808266,0.13707430384263497,0.9217383587835264,0.9585953053509725,0.619171741197861,0.13707430384263497,0.13707430384263497,3.6549956055948876,0.38263514328382814,-0.42998258634220327,-0.7101048204413503,0.342355682402477,-0.032043988936474706,-0.6153160198205229,4.697545811150349,0.580344223839915,-0.1619123131620609,0.2199786322467286,0.7722057037721174,0.46244619964697814,0.38263514328382814,0.26103110464403734,0.9217383587835264,0.46244619964697814,4.183049042361933,-0.07503752950409251,2.4369781355796594,0.26103110464403734,-0.29451413807445087,-0.1619123131620609,0.580344223839915,-0.1619123131620609,2.6979179668449453,0.46244619964697814,0.5412829355853829,0.13707430384263497,0.13707430384263497,0.05307774962454346,0.05307774962454346,-0.25000179333226685,0.13707430384263497,1.1755156156311373,0.619171741197861,1.031696165695717,-0.25000179333226685,-0.07503752950409251,0.26103110464403734,-0.11832544439901459,0.38263514328382814,0.010659648604851009,-0.032043988936474706,1.031696165695717,0.8473984012280706,0.46244619964697814,0.010659648604851009,0.5019846818620551,0.42266415546022,0.8099100211162025,0.42266415546022,1.3855706609057188,0.5412829355853829,-0.5684611504154431,0.09521457913715693,0.7722057037721174,1.246272443990728,-0.1619123131620609,-0.11832544439901459,1.1398524773123389,-0.11832544439901459,-0.38449929077288447,0.8473984012280706,0.6961379107980552,1.2109881782657737,-0.5684611504154431,0.5019846818620551,-0.11832544439901459,1.246272443990728,0.6961379107980552,0.42266415546022,0.1786609951774037,2.669400494336479,0.8473984012280706,0.1786609951774037,1.031696165695717,3.8271781683887824,1.9155840365977252,-1.0035370570387363,0.9585953053509725,0.1786609951774037,0.657768615715268,0.13707430384263497	3367
Other glycan degradation	7	8	2.924862694201057	0.0034460823794457	O00462,P16278,P07686,P06865,Q9BTY2,O00754,P04066	Processes and pathways	KEGG Pathways	msigdb_kegg	66,68,119,84,153,208,94	66,208,210,94,84,119,68,153	2.5831453876103505,1.2109881782657737,1.2109881782657737,2.1041468018137355,2.3177928418789855,1.8193146884450921,2.554155818031785,1.5557134250916398	3367
Cation transmembrane transporter activity	17	53	2.915943281884724	0.003546149597124	P13073,Q13423,O43772,P47985,Q70HW3,Q9HC21,P30825,Q15043,Q9UI12,Q9H0U3,Q9Y487,Q9HD20,O75964,Q6P4Q7,P16615,Q99808,Q93050	Functions	GO Molecular function	msigdb_gomf	232,233,42,449,13,360,201,315,249,322,186,185,89,460,211,158,62	42,1639,2865,89,690,693,1215,1001,1896,2159,2710,2384,529,1385,1310,232,211,864,2249,1732,2871,1562,1989,201,1394,2719,2875,2591,449,3332,2781,645,2401,1011,871,1069,233,315,1584,460,13,1683,972,62,158,322,2218,1872,360,185,512,249,186	3.0585160335120065,-0.032043988936474706,-0.8063746087452964,2.227038925427992,0.5019846818620551,0.5019846818620551,0.1786609951774037,0.30182221516229196,-0.1619123131620609,-0.29451413807445087,-0.6625285072121776,-0.42998258634220327,0.619171741197861,0.09521457913715693,0.13707430384263497,1.1398524773123389,1.2109881782657737,0.38263514328382814,-0.33934491131952355,-0.07503752950409251,-0.8063746087452964,0.010659648604851009,-0.2058028271615026,1.246272443990728,0.09521457913715693,-0.6625285072121776,-0.8063746087452964,-0.5684611504154431,0.6961379107980552,-2.024062737158297,-0.7101048204413503,0.5412829355853829,-0.42998258634220327,0.30182221516229196,0.38263514328382814,0.26103110464403734,1.1398524773123389,0.9217383587835264,0.010659648604851009,0.6961379107980552,4.433541950109594,-0.032043988936474706,0.342355682402477,2.669400494336479,1.522027904662708,0.9217383587835264,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.3510176219205223,0.657768615715268,1.103996441331084,1.3510176219205223	3367
Cherry red spot of the macula	7	9	2.908600043148827	0.0036305099557798	P07602,P16278,P10619,P17900,P07686,P06865,Q13510	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,68,106,107,119,84,90	84,34,119,106,2769,68,107,90,222	2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,-0.7101048204413503,2.554155818031785,1.9155840365977252,2.227038925427992,1.2109881782657737	3367
Lytic vacuole organization	11	25	2.889841858416229	0.0038543566934665	Q86VS8,Q14108,P54802,P11117,P10253,O14773,P07686,O75503,P04062,P50897,Q12768	Processes and pathways	GO Biological process	msigdb_gobp	161,32,65,37,143,20,119,24,210,29,127	1713,20,24,1553,210,119,143,37,448,29,1907,65,2001,127,32,821,161,257,1349,1608,2212,1043,2044,2575,2049	-0.07503752950409251,3.9953969719732,3.8514472696790003,0.010659648604851009,1.2109881782657737,1.8193146884450921,1.5892312826899408,3.192469446149936,0.6961379107980552,3.679843814797915,-0.1619123131620609,2.640766626646635,-0.2058028271615026,1.7216629695769743,3.5799366048175845,0.42266415546022,1.4881728202808266,1.0679451413858796,0.13707430384263497,0.010659648604851009,-0.29451413807445087,0.30182221516229196,-0.2058028271615026,-0.5219578544209845,-0.2058028271615026	3367
Membrane lipid catabolic process	9	12	2.8897347245530325	0.0038556703960848	O95470,P06280,P17900,P07686,P06865,P04062,Q13510,P50897,P04066	Processes and pathways	GO Biological process	msigdb_gobp	160,67,107,119,84,210,90,29,94	160,210,94,67,84,119,107,29,1410,90,273,561	1.4881728202808266,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,1.9155840365977252,3.679843814797915,0.09521457913715693,2.227038925427992,1.031696165695717,0.619171741197861	3367
Vacuolar membrane	34	116	2.872016429757827	0.0040786176178186	P42785,Q8WTV0,Q9Y2Q5,P42892,O15260,P10253,Q8IV08,O75503,P11279,P13473,Q14108,P07602,P11117,P20645,Q16625,Q14849,Q15043,O15118,Q9H0U3,Q9Y487,Q93050,O00462,Q8IY95,Q9NZJ7,Q92542,P04062,P41440,Q9UIQ6,Q07065,P10619,Q9UI12,P27105,O75955,Q8N511	Localization	GO Cellular component	msigdb_gocc	2,5,281,12,14,143,151,24,150,30,32,34,37,44,168,49,315,46,322,186,62,66,336,222,218,210,102,103,225,106,249,114,238,257	1713,66,1465,46,14,685,1205,1890,1891,1641,2313,688,24,238,631,1382,918,210,919,2159,34,2710,2384,2711,2319,1897,143,106,37,2712,150,30,44,1732,2871,2821,114,2718,1314,2875,2591,2721,102,448,2,12,2172,2598,1907,641,1142,870,1746,3283,2001,1011,1492,2087,2467,1232,2785,225,1324,1014,1838,1663,32,49,315,168,821,151,336,257,883,2846,5,2690,553,218,62,1349,1433,761,1523,2360,889,1608,339,1097,2804,1099,2568,1038,2039,322,3073,2040,2499,2852,2044,2570,222,1708,2575,616,249,103,778,3322,1710,281,412,3145,186,3112	-0.07503752950409251,2.5831453876103505,0.05307774962454346,2.8943684331092254,4.34342738654226,0.5019846818620551,0.1786609951774037,-0.1619123131620609,-0.1619123131620609,-0.032043988936474706,-0.38449929077288447,0.5019846818620551,3.8514472696790003,1.103996441331084,0.5412829355853829,0.09521457913715693,0.342355682402477,1.2109881782657737,0.342355682402477,-0.29451413807445087,3.297852942116772,-0.6625285072121776,-0.42998258634220327,-0.6625285072121776,-0.38449929077288447,-0.1619123131620609,1.5892312826899408,1.9473741733456051,3.192469446149936,-0.6625285072121776,1.5557134250916398,3.6549956055948876,2.976917059317765,-0.07503752950409251,-0.8063746087452964,-0.7580513366787757,1.8515558846925475,-0.6625285072121776,0.13707430384263497,-0.8063746087452964,-0.5684611504154431,-0.6625285072121776,2.0105143282367153,0.6961379107980552,6.292167445838333,4.697545811150349,-0.29451413807445087,-0.5684611504154431,-0.1619123131620609,0.5412829355853829,0.2199786322467286,0.38263514328382814,-0.07503752950409251,-1.5776059098511652,-0.2058028271615026,0.30182221516229196,0.05307774962454346,-0.25000179333226685,-0.4758002447614249,0.1786609951774037,-0.7101048204413503,1.1755156156311373,0.13707430384263497,0.30182221516229196,-0.11832544439901459,-0.032043988936474706,3.5799366048175845,2.8943684331092254,0.9217383587835264,1.419946185566603,0.42266415546022,1.5557134250916398,0.884673610049861,1.0679451413858796,0.38263514328382814,-0.7580513366787757,5.895453047698817,-0.6153160198205229,0.619171741197861,1.2109881782657737,2.669400494336479,0.13707430384263497,0.09521457913715693,0.46244619964697814,0.05307774962454346,-0.38449929077288447,0.38263514328382814,0.010659648604851009,0.884673610049861,0.26103110464403734,-0.7101048204413503,0.26103110464403734,-0.5219578544209845,0.30182221516229196,-0.2058028271615026,0.9217383587835264,-1.0035370570387363,-0.2058028271615026,-0.4758002447614249,-0.7580513366787757,-0.2058028271615026,-0.5219578544209845,1.2109881782657737,-0.032043988936474706,-0.5219578544209845,0.580344223839915,1.103996441331084,2.0105143282367153,0.46244619964697814,-1.853811091154964,-0.032043988936474706,1.031696165695717,0.7722057037721174,-1.1044492003404638,1.3510176219205223,-1.053799466605388	3367
Ceramide metabolic process	10	18	2.8340174803714624	0.0045966817508227	Q8NCC3,O95470,P06280,Q96G23,P17900,P07686,Q99805,P06865,Q13510,P04062	Processes and pathways	GO Biological process	msigdb_gobp	0,160,67,38,107,119,184,84,90,210	282,1204,160,210,67,84,119,107,1899,2251,1410,1496,90,1335,0,38,184,561	0.995247055805408,0.1786609951774037,1.4881728202808266,1.2109881782657737,2.554155818031785,2.3177928418789855,1.8193146884450921,1.9155840365977252,-0.1619123131620609,-0.33934491131952355,0.09521457913715693,0.05307774962454346,2.227038925427992,0.13707430384263497,6.753408671655479,3.192469446149936,1.3510176219205223,0.619171741197861	3367
Glycoprotein metabolic process	23	57	2.8089999890531714	0.0049695648278438	Q86SF2,P35222,P35610,Q6ZXV5,O15118,Q99805,P46977,Q9H0U3,Q8WVQ1,O60502,O00462,Q10471,Q16706,O60476,Q92542,Q10472,Q08379,O00754,Q2TAA5,Q7LGA3,Q8TCJ2,O75352,O43505	Processes and pathways	GO Biological process	msigdb_gobp	256,531,532,297,46,184,422,322,318,64,66,312,335,81,218,452,212,208,350,374,661,363,122	66,1548,208,2235,46,2308,122,81,64,1642,2446,1812,3325,363,2706,1983,919,1648,531,532,2721,422,2544,2263,2180,872,2408,212,312,452,1327,1329,2096,335,350,297,374,1853,256,1776,661,318,218,3071,1606,3304,184,2034,1787,322,674,1106,1112,1187,2144,905,1121	2.5831453876103505,0.010659648604851009,1.2109881782657737,-0.33934491131952355,2.8943684331092254,-0.38449929077288447,1.7869199137107399,2.377641277448686,2.640766626646635,-0.032043988936474706,-0.4758002447614249,-0.11832544439901459,-1.9101855426565795,0.8099100211162025,-0.6625285072121776,-0.2058028271615026,0.342355682402477,-0.032043988936474706,0.619171741197861,0.619171741197861,-0.6625285072121776,0.7342826270023676,-0.5219578544209845,-0.33934491131952355,-0.29451413807445087,0.38263514328382814,-0.42998258634220327,1.2109881782657737,0.9217383587835264,0.6961379107980552,0.13707430384263497,0.13707430384263497,-0.25000179333226685,0.884673610049861,0.8473984012280706,0.9585953053509725,0.8099100211162025,-0.11832544439901459,1.0679451413858796,-0.07503752950409251,0.5412829355853829,0.9217383587835264,1.2109881782657737,-1.0035370570387363,0.010659648604851009,-1.7421936575233459,1.3510176219205223,-0.2058028271615026,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.26103110464403734,0.26103110464403734,0.2199786322467286,-0.25000179333226685,0.38263514328382814,0.26103110464403734	3367
Hydrolase activity hydrolyzing o glycosyl compounds	13	23	2.8012931227841693	0.0050898263809482	O60502,P54802,O00462,P06280,P16278,P17900,O60476,P10253,P07686,P06865,Q9BTY2,O00754,P04066	Functions	GO Molecular function	msigdb_gomf	64,65,66,67,68,107,81,143,119,84,153,208,94	66,208,81,64,210,94,67,84,119,143,68,107,1135,65,3015,1327,2096,335,1592,153,1536,3107,1882	2.5831453876103505,1.2109881782657737,2.377641277448686,2.640766626646635,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,1.5892312826899408,2.554155818031785,1.9155840365977252,0.2199786322467286,2.640766626646635,-0.9536627270282968,0.13707430384263497,-0.25000179333226685,0.884673610049861,0.010659648604851009,1.5557134250916398,0.05307774962454346,-1.053799466605388,-0.11832544439901459	3367
Glycoside hydrolase superfamily [IPR017853]	10	16	2.796625215827265	0.0051639396582707	O60502,P54802,O00462,P06280,P16278,P10253,P06865,P07686,Q9BTY2,P04066	Sequence	InterPro Superfamily	interpro_homologous_superfamily	64,65,66,67,68,143,84,119,153,94	66,64,210,94,67,84,119,2384,143,68,1135,65,3015,2096,153,1273	2.5831453876103505,2.640766626646635,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,-0.42998258634220327,1.5892312826899408,2.554155818031785,0.2199786322467286,2.640766626646635,-0.9536627270282968,-0.25000179333226685,1.5557134250916398,0.1786609951774037	3367
Liposaccharide metabolic process	10	16	2.7807906414636947	0.0054226695345462	Q8NBX0,P06280,P16278,Q9H490,P17900,Q99805,P06865,P07686,P04062,P04066	Processes and pathways	GO Biological process	msigdb_gobp	230,67,68,235,107,184,84,119,210,94	1812,210,94,67,84,119,68,107,1410,1496,230,1601,718,380,184,235	-0.11832544439901459,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,2.554155818031785,1.9155840365977252,0.09521457913715693,0.05307774962454346,1.1755156156311373,0.010659648604851009,0.5019846818620551,0.8099100211162025,1.3510176219205223,1.1398524773123389	3367
Glycosaminoglycan metabolism	8	12	2.757794201390491	0.0058192821539795	P54802,P16278,O43252,P15586,P07686,P06865,Q8TB61,O43505	Processes and pathways	Reactome Pathways	msigdb_reactome	65,68,329,85,119,84,270,122	329,122,1000,84,119,85,68,65,374,270,1606,2144	0.884673610049861,1.7869199137107399,0.30182221516229196,2.3177928418789855,1.8193146884450921,2.3177928418789855,2.554155818031785,2.640766626646635,0.8099100211162025,1.031696165695717,0.010659648604851009,-0.25000179333226685	3367
Sphingolipid metabolism	14	25	2.752271626595673	0.0059183409251639	O95470,P07602,P06280,P16278,O15269,Q96G23,P10619,Q06136,P17900,Q9NZJ7,P07686,P06865,Q13510,P04062	Processes and pathways	Reactome Pathways	msigdb_reactome	160,34,67,68,282,38,106,11,107,222,119,84,90,210	989,282,1204,2814,1723,160,210,67,84,34,119,106,633,68,107,924,1899,333,11,90,38,2625,561,222,1708	0.30182221516229196,0.995247055805408,0.1786609951774037,-0.7580513366787757,-0.07503752950409251,1.4881728202808266,1.2109881782657737,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,0.5412829355853829,2.554155818031785,1.9155840365977252,0.342355682402477,-0.1619123131620609,0.884673610049861,4.783524978682848,2.227038925427992,3.192469446149936,-0.5684611504154431,0.619171741197861,1.2109881782657737,-0.032043988936474706	3367
Sphingolipid metabolism	6	9	2.7449840707003683	0.0060513834919309	O95470,P07602,Q06136,P17900,Q13510,P04062	Processes and pathways	Protein Atlas Biological process	protein_atlas_biological_process	160,34,11,107,90,210	282,1204,160,210,34,107,11,90,471	0.995247055805408,0.1786609951774037,1.4881728202808266,1.2109881782657737,3.297852942116772,1.9155840365977252,4.783524978682848,2.227038925427992,0.6961379107980552	3367
Membrane microdomain	15	67	2.733928205147558	0.006258368878514	P19022,P21796,Q8WTV0,P41440,P09104,P09601,Q9Y2Q5,O15118,P05067,O14773,P27105,O75955,O00560,P50897,P13473	Localization	GO Cellular component	msigdb_gocc	346,309,5,102,196,40,281,46,83,20,114,238,188,29,30	522,188,1889,20,46,1890,238,2315,2157,3170,528,1215,83,1001,2064,3231,2159,1057,2319,196,40,1058,1556,30,2067,2323,1730,346,1311,864,2388,309,2073,1989,114,2960,2873,1991,1221,531,2920,635,2668,102,1137,1740,1906,29,1230,1833,1014,2789,873,1758,747,369,821,2115,5,3217,3304,1099,2758,1964,2226,1627,281	0.619171741197861,1.3162849902600815,-0.1619123131620609,3.9953969719732,2.8943684331092254,-0.1619123131620609,1.103996441331084,-0.38449929077288447,-0.29451413807445087,-1.206907661975204,0.619171741197861,0.1786609951774037,2.3477816274627044,0.30182221516229196,-0.25000179333226685,-1.3634818904670298,-0.29451413807445087,0.26103110464403734,-0.38449929077288447,1.2813706494606423,3.1123997852653797,0.26103110464403734,0.010659648604851009,3.6549956055948876,-0.25000179333226685,-0.38449929077288447,-0.07503752950409251,0.8473984012280706,0.13707430384263497,0.38263514328382814,-0.42998258634220327,0.9217383587835264,-0.25000179333226685,-0.2058028271615026,1.8515558846925475,-0.9041772408267448,-0.8063746087452964,-0.2058028271615026,0.1786609951774037,0.619171741197861,-0.8550813717441338,0.5412829355853829,-0.6153160198205229,2.0105143282367153,0.2199786322467286,-0.07503752950409251,-0.1619123131620609,3.679843814797915,0.1786609951774037,-0.11832544439901459,0.30182221516229196,-0.7101048204413503,0.38263514328382814,-0.07503752950409251,0.46244619964697814,0.8099100211162025,0.42266415546022,-0.25000179333226685,5.895453047698817,-1.3109065691871442,-1.7421936575233459,0.26103110464403734,-0.6625285072121776,-0.1619123131620609,-0.29451413807445087,0.010659648604851009,1.031696165695717	3367
Skeletal muscle hypertrophy	12	52	2.7302729200713545	0.0063281912781105	Q10713,P16278,Q9Y4P3,Q7LGA3,Q9NR77,Q96S52,O43933,P10253,P07686,O00754,P04066,P60891	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	287,68,302,374,278,380,15,143,119,208,94,31	907,570,208,1054,1202,1979,15,911,2815,389,2315,1816,94,119,143,68,1732,2164,2254,934,2078,805,1141,31,1403,1405,1408,2091,287,1238,1240,2186,2093,747,3284,1245,2928,374,2024,831,1349,380,1096,2899,1275,278,1278,2225,514,1456,302,905	0.342355682402477,0.580344223839915,1.2109881782657737,0.26103110464403734,0.1786609951774037,-0.2058028271615026,4.320727255133443,0.342355682402477,-0.7580513366787757,0.7722057037721174,-0.38449929077288447,-0.11832544439901459,2.1041468018137355,1.8193146884450921,1.5892312826899408,2.554155818031785,-0.07503752950409251,-0.29451413807445087,-0.33934491131952355,0.342355682402477,-0.25000179333226685,0.42266415546022,0.2199786322467286,3.6549956055948876,0.09521457913715693,0.09521457913715693,0.09521457913715693,-0.25000179333226685,0.995247055805408,0.1786609951774037,0.1786609951774037,-0.29451413807445087,-0.25000179333226685,0.46244619964697814,-1.5776059098511652,0.1786609951774037,-0.8550813717441338,0.8099100211162025,-0.2058028271615026,0.42266415546022,0.13707430384263497,0.8099100211162025,0.26103110464403734,-0.8063746087452964,0.1786609951774037,1.031696165695717,0.1786609951774037,-0.29451413807445087,0.657768615715268,0.09521457913715693,0.9585953053509725,0.38263514328382814	3367
Glycosidase	12	19	2.7112848245724077	0.0067023026363473	O60502,P54802,O00462,P06280,P16278,O60476,P10253,P07686,P06865,Q9BTY2,O00754,P04066	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	64,65,66,67,68,81,143,119,84,153,208,94	66,208,3259,81,64,210,94,67,84,119,143,68,1135,65,2344,1327,2096,335,153	2.5831453876103505,1.2109881782657737,-1.4697807385854578,2.377641277448686,2.640766626646635,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,1.5892312826899408,2.554155818031785,0.2199786322467286,2.640766626646635,-0.38449929077288447,0.13707430384263497,-0.25000179333226685,0.884673610049861,1.5557134250916398	3367
Dementia	18	61	2.7098602493896142	0.0067311562827248	Q14108,P07602,O96008,P61916,Q13510,Q96RL7,P17900,O15118,Q9NZJ7,P05067,Q9Y487,P42858,P06865,Q8IY17,Q9NQZ5,P04062,O60313,P04350	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,34,308,99,90,339,107,46,222,83,186,265,84,316,323,210,209,366	1635,46,2814,209,688,364,308,693,210,3337,366,83,84,34,1305,1476,633,107,1218,2164,2072,865,1899,576,2168,421,2875,2591,265,933,1829,1568,1745,99,3015,1919,1837,1923,945,90,32,1330,877,2484,3133,316,2199,758,970,1519,1608,339,721,3304,323,222,2143,1373,2994,186,3299	-0.032043988936474706,2.8943684331092254,-0.7580513366787757,1.2109881782657737,0.5019846818620551,0.8099100211162025,0.9217383587835264,0.5019846818620551,1.2109881782657737,-2.197689911987167,0.8099100211162025,2.3477816274627044,2.3177928418789855,3.297852942116772,0.13707430384263497,0.05307774962454346,0.5412829355853829,1.9155840365977252,0.1786609951774037,-0.29451413807445087,-0.25000179333226685,0.38263514328382814,-0.1619123131620609,0.580344223839915,-0.29451413807445087,0.7342826270023676,-0.8063746087452964,-0.5684611504154431,1.031696165695717,0.342355682402477,-0.11832544439901459,0.010659648604851009,-0.07503752950409251,2.041867375489916,-0.9536627270282968,-0.1619123131620609,-0.11832544439901459,-0.1619123131620609,0.342355682402477,2.227038925427992,3.5799366048175845,0.13707430384263497,0.38263514328382814,-0.4758002447614249,-1.1044492003404638,0.9217383587835264,-0.29451413807445087,0.46244619964697814,0.342355682402477,0.05307774962454346,0.010659648604851009,0.884673610049861,0.5019846818620551,-1.7421936575233459,0.9217383587835264,1.2109881782657737,-0.25000179333226685,0.13707430384263497,-0.9041772408267448,1.3510176219205223,-1.686951965968084	3367
Azurophil granule lumen	13	42	2.700202303534635	0.0069297323735417	P06280,Q99536,P16278,P61916,P10619,Q92820,P17900,O00584,P15586,P07686,Q9BTY2,O00560,P04066	Localization	GO Cellular component	msigdb_gocc	67,164,68,99,106,139,107,53,85,119,153,188,94	188,53,208,2814,2241,94,67,2159,1057,119,106,2320,633,85,68,107,1479,2873,3247,3013,2831,2336,869,2465,1745,2466,99,1146,2343,2404,1410,1497,1761,2355,139,1522,2623,164,153,2217,2224,2228	1.3162849902600815,2.782782542710472,1.2109881782657737,-0.7580513366787757,-0.33934491131952355,2.1041468018137355,2.554155818031785,-0.29451413807445087,0.26103110464403734,1.8193146884450921,1.9473741733456051,-0.38449929077288447,0.5412829355853829,2.3177928418789855,2.554155818031785,1.9155840365977252,0.05307774962454346,-0.8063746087452964,-1.416440179685344,-0.9536627270282968,-0.7580513366787757,-0.38449929077288447,0.38263514328382814,-0.4758002447614249,-0.07503752950409251,-0.4758002447614249,2.041867375489916,0.2199786322467286,-0.38449929077288447,-0.42998258634220327,0.09521457913715693,0.05307774962454346,-0.07503752950409251,-0.38449929077288447,1.6225833456176855,0.05307774962454346,-0.5684611504154431,1.4541462370669627,1.5557134250916398,-0.29451413807445087,-0.29451413807445087,-0.29451413807445087	3367
Aminoglycan metabolic process	6	13	2.698032033249179	0.0069750728489661	P54802,P16278,P07686,P15586,P06865,P04066	Processes and pathways	GO Biological process	msigdb_gobp	65,68,119,85,84,94	122,2446,918,94,84,119,85,68,65,1232,2181,374,1606	1.7869199137107399,-0.4758002447614249,0.342355682402477,2.1041468018137355,2.3177928418789855,1.8193146884450921,2.3177928418789855,2.554155818031785,2.640766626646635,0.1786609951774037,-0.29451413807445087,0.8099100211162025,0.010659648604851009	3367
Carbohydrate derivative transport	9	14	2.6937502991617177	0.0070653073828101	P07602,P61916,Q8WTV0,P41440,L0R6Q1,Q9NZJ7,Q99808,Q8TB61,Q9HC21	Processes and pathways	GO Biological process	msigdb_gobp	34,99,5,102,251,222,158,270,360	251,1639,1001,34,1310,419,102,99,2019,270,5,158,360,222	1.0679451413858796,-0.032043988936474706,0.30182221516229196,3.297852942116772,0.13707430384263497,0.7342826270023676,2.0105143282367153,2.041867375489916,-0.2058028271615026,1.031696165695717,5.895453047698817,1.522027904662708,0.8473984012280706,1.2109881782657737	3367
Late endosome	18	65	2.6822731125277124	0.0073123734855449	Q14108,P07602,Q8IY95,Q9Y2Q5,P20645,Q14849,Q15043,Q9BRK5,Q99538,Q9ULH0,P13473,O15118,Q8IV08,P42858,Q9NZJ7,Q8TAF3,P11279,P11717	Localization	GO Cellular component	msigdb_gocc	32,34,336,281,44,49,315,146,177,179,30,46,151,265,222,377,150,156	2053,787,46,1205,2905,1890,2817,2159,34,2710,1058,2712,150,156,30,2658,44,2960,2873,3173,265,1907,2001,1917,945,32,49,315,1508,654,821,151,336,1681,2616,377,2690,1349,1433,2360,1607,1608,839,177,975,2984,146,407,1273,2133,3073,2040,2219,897,2044,222,2575,2758,3141,179,3322,1710,281,988,784	-0.25000179333226685,0.42266415546022,2.8943684331092254,0.1786609951774037,-0.8550813717441338,-0.1619123131620609,-0.7580513366787757,-0.29451413807445087,3.297852942116772,-0.6625285072121776,0.26103110464403734,-0.6625285072121776,1.5557134250916398,1.522027904662708,3.6549956055948876,-0.6153160198205229,2.976917059317765,-0.9041772408267448,-0.8063746087452964,-1.206907661975204,1.031696165695717,-0.1619123131620609,-0.2058028271615026,-0.1619123131620609,0.342355682402477,3.5799366048175845,2.8943684331092254,0.9217383587835264,0.05307774962454346,0.5412829355853829,0.42266415546022,1.5557134250916398,0.884673610049861,-0.032043988936474706,-0.5684611504154431,0.8099100211162025,-0.6153160198205229,0.13707430384263497,0.09521457913715693,-0.38449929077288447,0.010659648604851009,0.010659648604851009,0.42266415546022,1.3855706609057188,0.342355682402477,-0.9041772408267448,1.5892312826899408,0.7722057037721174,0.1786609951774037,-0.25000179333226685,-1.0035370570387363,-0.2058028271615026,-0.29451413807445087,0.38263514328382814,-0.2058028271615026,1.2109881782657737,-0.5219578544209845,-0.6625285072121776,-1.1044492003404638,1.3855706609057188,-1.853811091154964,-0.032043988936474706,1.031696165695717,0.342355682402477,0.46244619964697814	3367
Hallucinations	15	52	2.679227377363747	0.007379226586204	Q6DKK2,P07602,O96008,P19022,O00754,Q9NZJ7,P05067,P35637,P42858,O75503,P04062,Q9BQE5,O76024,P50897,O60313	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	97,34,308,346,208,222,83,421,265,24,210,27,364,29,209	2761,1635,208,2814,209,688,24,364,308,210,83,34,3207,2245,633,1003,346,446,1391,736,421,1900,533,265,1484,2170,29,2080,1398,581,2082,1745,2675,1919,1411,1923,945,2931,97,2484,3133,1165,2199,1608,3304,27,1444,222,1285,854,1373,3299	-0.7101048204413503,-0.032043988936474706,1.2109881782657737,-0.7580513366787757,1.2109881782657737,0.5019846818620551,3.8514472696790003,0.8099100211162025,0.9217383587835264,1.2109881782657737,2.3477816274627044,3.297852942116772,-1.3109065691871442,-0.33934491131952355,0.5412829355853829,0.30182221516229196,0.8473984012280706,0.6961379107980552,0.09521457913715693,0.46244619964697814,0.7342826270023676,-0.1619123131620609,0.619171741197861,1.031696165695717,0.05307774962454346,-0.29451413807445087,3.679843814797915,-0.25000179333226685,0.09521457913715693,0.580344223839915,-0.25000179333226685,-0.07503752950409251,-0.6153160198205229,-0.1619123131620609,0.09521457913715693,-0.1619123131620609,0.342355682402477,-0.8550813717441338,2.0730777150539357,-0.4758002447614249,-1.1044492003404638,0.2199786322467286,-0.29451413807445087,0.010659648604851009,-1.7421936575233459,3.7292869846617753,0.09521457913715693,1.2109881782657737,0.1786609951774037,0.42266415546022,0.13707430384263497,-1.686951965968084	3367
Glycoprotein biosynthetic process	21	50	2.6334301354492675	0.0084527223769572	Q86SF2,P35222,P35610,Q6ZXV5,O15118,Q99805,P46977,Q9H0U3,Q8WVQ1,O60502,Q10471,Q16706,O60476,Q92542,Q10472,Q08379,Q2TAA5,Q7LGA3,Q8TCJ2,O75352,O43505	Processes and pathways	GO Biological process	msigdb_gobp	256,531,532,297,46,184,422,322,318,64,312,335,81,218,452,212,350,374,661,363,122	1548,2235,46,2308,122,81,64,1642,2446,1812,3325,363,2706,1983,919,531,532,2721,422,2544,2180,872,2408,212,312,452,1327,1329,335,350,297,374,1853,256,1776,661,318,218,3071,1606,184,1787,322,674,1106,1112,1187,2144,905,1121	0.010659648604851009,-0.33934491131952355,2.8943684331092254,-0.38449929077288447,1.7869199137107399,2.377641277448686,2.640766626646635,-0.032043988936474706,-0.4758002447614249,-0.11832544439901459,-1.9101855426565795,0.8099100211162025,-0.6625285072121776,-0.2058028271615026,0.342355682402477,0.619171741197861,0.619171741197861,-0.6625285072121776,0.7342826270023676,-0.5219578544209845,-0.29451413807445087,0.38263514328382814,-0.42998258634220327,1.2109881782657737,0.9217383587835264,0.6961379107980552,0.13707430384263497,0.13707430384263497,0.884673610049861,0.8473984012280706,0.9585953053509725,0.8099100211162025,-0.11832544439901459,1.0679451413858796,-0.07503752950409251,0.5412829355853829,0.9217383587835264,1.2109881782657737,-1.0035370570387363,0.010659648604851009,1.3510176219205223,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.26103110464403734,0.26103110464403734,0.2199786322467286,-0.25000179333226685,0.38263514328382814,0.26103110464403734	3367
Azurophil granule membrane	11	22	2.6244718924232475	0.008678345518577	P42785,P07602,O00462,Q07065,O15260,Q9NZJ7,P10253,P27105,Q92542,P11279,P13473	Localization	GO Cellular component	msigdb_gocc	2,34,66,225,14,222,143,114,218,150,30	66,14,2313,688,1382,34,143,150,30,114,2721,2,2598,225,821,883,218,1433,2804,322,222,1708	2.5831453876103505,4.34342738654226,-0.38449929077288447,0.5019846818620551,0.09521457913715693,3.297852942116772,1.5892312826899408,1.5557134250916398,3.6549956055948876,1.8515558846925475,-0.6625285072121776,6.292167445838333,-0.5684611504154431,1.1755156156311373,0.42266415546022,0.38263514328382814,1.2109881782657737,0.09521457913715693,-0.7101048204413503,0.9217383587835264,1.2109881782657737,-0.032043988936474706	3367
Glycerophospholipid metabolic process	16	59	2.6073647436944816	0.0091242109935094	Q92604,Q8NCC3,Q10713,Q9BZF1,Q8N9F7,Q8WTV0,Q96N66,P42356,Q96Q15,Q9H490,Q96S52,P35790,O95674,Q86TV6,Q8IY17,Q9UG56	Processes and pathways	GO Biological process	msigdb_gobp	259,0,287,192,403,5,133,198,98,235,380,48,330,182,316,361	3200,570,1975,624,2702,1812,1129,330,3230,2956,1730,1390,3189,3247,48,932,198,1485,738,1829,1571,287,1073,1663,426,182,1774,316,659,403,0,883,2202,5,3069,758,259,1601,718,2122,133,98,380,3321,975,2750,2032,1099,1951,1359,192,1868,235,2696,1706,561,361,1964,566	-1.3109065691871442,0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.11832544439901459,0.2199786322467286,0.884673610049861,-1.3634818904670298,-0.9041772408267448,-0.07503752950409251,0.09521457913715693,-1.2587149217723634,-1.416440179685344,2.8943684331092254,0.342355682402477,1.2813706494606423,0.05307774962454346,0.46244619964697814,-0.11832544439901459,0.010659648604851009,0.995247055805408,0.26103110464403734,-0.032043988936474706,0.7342826270023676,1.3510176219205223,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.7722057037721174,6.753408671655479,0.38263514328382814,-0.29451413807445087,5.895453047698817,-1.0035370570387363,0.46244619964697814,1.0679451413858796,0.010659648604851009,0.5019846818620551,-0.25000179333226685,1.6557714498436458,2.0730777150539357,0.8099100211162025,-1.853811091154964,0.342355682402477,-0.6625285072121776,-0.2058028271615026,0.26103110464403734,-0.1619123131620609,0.13707430384263497,1.3162849902600815,-0.11832544439901459,1.1398524773123389,-0.6153160198205229,-0.032043988936474706,0.619171741197861,0.8473984012280706,-0.1619123131620609,0.619171741197861	3367
Glycosphingolipid metabolism	9	15	2.603686099708991	0.0092227182318171	P07602,P06280,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510	Processes and pathways	Reactome Pathways	msigdb_reactome	34,67,68,106,107,222,119,84,90	989,2814,210,67,84,34,119,106,633,68,107,90,2625,561,222	0.30182221516229196,-0.7580513366787757,1.2109881782657737,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,0.5412829355853829,2.554155818031785,1.9155840365977252,2.227038925427992,-0.5684611504154431,0.619171741197861,1.2109881782657737	3367
Exopeptidase activity	13	31	2.586231671864463	0.0097031687585233	Q9H3G5,P42785,P55786,Q9UIQ6,P10619,Q92820,Q9NZ08,Q9HB40,O75976,O75844,O14773,Q96DE0,Q9NQH7	Functions	GO Molecular function	msigdb_gomf	1,2,162,103,106,139,148,16,175,113,20,219,61	20,113,175,239,3005,106,2657,2456,2326,1900,2,2597,869,162,3264,1241,3194,2117,139,1780,219,2124,2804,1,1954,16,61,3106,2573,148,103	3.9953969719732,1.8515558846925475,1.3855706609057188,1.103996441331084,-0.9536627270282968,1.9473741733456051,-0.6153160198205229,-0.4758002447614249,-0.38449929077288447,-0.1619123131620609,6.292167445838333,-0.5684611504154431,0.38263514328382814,1.4541462370669627,-1.4697807385854578,0.1786609951774037,-1.2587149217723634,-0.25000179333226685,1.6225833456176855,-0.07503752950409251,1.2109881782657737,-0.25000179333226685,-0.7101048204413503,6.653184264123767,-0.1619123131620609,4.320727255133443,2.6979179668449453,-1.053799466605388,-0.5219578544209845,1.5892312826899408,2.0105143282367153	3367
Abnormal vascular physiology	13	58	2.5696954864220563	0.0101787944490738	Q14108,Q71SY5,Q5T2R2,O95235,P06280,Q9Y4P3,Q14739,Q9NZ08,O75844,Q96HP0,P05067,Q8IZA0,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,33,255,284,67,302,76,148,113,272,83,152,210	570,3034,1979,1642,1644,3229,113,284,2866,693,294,1816,210,1555,83,67,1386,1003,2249,1559,1989,2774,3151,531,2254,1738,1484,1740,2079,641,2177,644,1405,872,3159,1240,32,1500,76,3284,255,1419,1510,2019,33,152,828,1349,272,2695,148,615,2225,514,1115,1460,302,3299	0.580344223839915,-1.0035370570387363,-0.2058028271615026,-0.032043988936474706,-0.032043988936474706,-1.3634818904670298,1.8515558846925475,0.995247055805408,-0.8063746087452964,0.5019846818620551,0.9585953053509725,-0.11832544439901459,1.2109881782657737,0.010659648604851009,2.3477816274627044,2.554155818031785,0.09521457913715693,0.30182221516229196,-0.33934491131952355,0.010659648604851009,-0.2058028271615026,-0.7101048204413503,-1.1554855115344582,0.619171741197861,-0.33934491131952355,-0.07503752950409251,0.05307774962454346,-0.07503752950409251,-0.25000179333226685,0.5412829355853829,-0.29451413807445087,0.5412829355853829,0.09521457913715693,0.38263514328382814,-1.1554855115344582,0.1786609951774037,3.5799366048175845,0.05307774962454346,2.4369781355796594,-1.5776059098511652,1.0679451413858796,0.09521457913715693,0.05307774962454346,-0.2058028271615026,3.4530829773454683,1.5557134250916398,0.42266415546022,0.13707430384263497,1.031696165695717,-0.6153160198205229,1.5892312826899408,0.580344223839915,-0.29451413807445087,0.657768615715268,0.26103110464403734,0.09521457913715693,0.9585953053509725,-1.686951965968084	3367
Endocytic vesicle membrane	11	40	2.540472590288584	0.0110702770493715	Q14108,P02786,Q8WTV0,P20645,Q12846,Q9Y487,P13473,Q93050,P11279,Q5KU26,P11717	Localization	GO Cellular component	msigdb_gocc	32,239,5,44,144,186,30,62,150,120,156	476,1295,2648,631,918,294,239,527,1307,150,156,30,2388,44,2774,2078,1907,1142,2676,2543,1011,2087,1232,1571,1324,144,491,2184,32,1929,2737,120,2108,5,62,761,975,2212,2858,186	0.657768615715268,0.13707430384263497,-0.6153160198205229,0.5412829355853829,0.342355682402477,0.9585953053509725,1.103996441331084,0.619171741197861,0.13707430384263497,1.5557134250916398,1.522027904662708,3.6549956055948876,-0.42998258634220327,2.976917059317765,-0.7101048204413503,-0.25000179333226685,-0.1619123131620609,0.2199786322467286,-0.6153160198205229,-0.5219578544209845,0.30182221516229196,-0.25000179333226685,0.1786609951774037,0.010659648604851009,0.13707430384263497,1.5892312826899408,0.657768615715268,-0.29451413807445087,3.5799366048175845,-0.1619123131620609,-0.6625285072121776,1.8193146884450921,-0.25000179333226685,5.895453047698817,2.669400494336479,0.46244619964697814,0.342355682402477,-0.29451413807445087,-0.7580513366787757,1.3510176219205223	3367
Hydrolase activity acting on glycosyl bonds	15	33	2.5305549852810265	0.0113882233658608	O60502,P54802,O00462,P06280,P16278,P17900,O60476,P10253,P07686,P06865,P13051,O75503,O00754,Q9BTY2,P04066	Functions	GO Molecular function	msigdb_gomf	64,65,66,67,68,107,81,143,119,84,189,24,208,153,94	66,208,3259,81,64,24,210,94,67,84,119,143,2768,189,68,107,2772,926,2587,1135,65,2344,3015,1327,2096,335,2558,1592,3334,153,1536,3107,1882	2.5831453876103505,1.2109881782657737,-1.4697807385854578,2.377641277448686,2.640766626646635,3.8514472696790003,1.2109881782657737,2.1041468018137355,2.554155818031785,2.3177928418789855,1.8193146884450921,1.5892312826899408,-0.7101048204413503,1.3162849902600815,2.554155818031785,1.9155840365977252,-0.7101048204413503,0.342355682402477,-0.5684611504154431,0.2199786322467286,2.640766626646635,-0.38449929077288447,-0.9536627270282968,0.13707430384263497,-0.25000179333226685,0.884673610049861,-0.5219578544209845,0.010659648604851009,-2.024062737158297,1.5557134250916398,0.05307774962454346,-1.053799466605388,-0.11832544439901459	3367
Receptor mediated endocytosis	9	57	2.5264659724950733	0.0115216549183718	Q14108,P41440,Q5VW38,P20645,P05067,P02786,O00560,P50897,P11717	Processes and pathways	GO Biological process	msigdb_gobp	32,102,9,44,83,239,188,29,156	2762,476,188,2511,1891,688,238,631,918,239,83,2064,2159,1897,795,156,2323,2388,44,2073,927,2328,102,1902,1009,2078,29,1142,1403,2968,2546,1832,2087,1232,2404,1837,1324,1577,3056,1663,32,1578,3098,3266,2737,9,2198,2616,1167,761,1702,3256,3143,986,2051,1888,2579	-0.7101048204413503,0.657768615715268,1.3162849902600815,-0.5219578544209845,-0.1619123131620609,0.5019846818620551,1.103996441331084,0.5412829355853829,0.342355682402477,1.103996441331084,2.3477816274627044,-0.25000179333226685,-0.29451413807445087,-0.1619123131620609,0.42266415546022,1.522027904662708,-0.38449929077288447,-0.42998258634220327,2.976917059317765,-0.25000179333226685,0.342355682402477,-0.38449929077288447,2.0105143282367153,-0.1619123131620609,0.30182221516229196,-0.25000179333226685,3.679843814797915,0.2199786322467286,0.09521457913715693,-0.9041772408267448,-0.5219578544209845,-0.11832544439901459,-0.25000179333226685,0.1786609951774037,-0.42998258634220327,-0.11832544439901459,0.13707430384263497,0.010659648604851009,-1.0035370570387363,-0.032043988936474706,3.5799366048175845,0.010659648604851009,-1.053799466605388,-1.4697807385854578,-0.6625285072121776,4.82614995544459,-0.29451413807445087,-0.5684611504154431,0.2199786322467286,0.46244619964697814,-0.032043988936474706,-1.416440179685344,-1.1044492003404638,0.342355682402477,-0.2058028271615026,-0.11832544439901459,-0.5219578544209845	3367
Sterol metabolic process	12	40	2.5118543370644555	0.0120098649470172	P61916,Q8WTV0,Q15800,Q14739,Q14849,O15118,P05067,P34913,Q9BQE5,Q15392,Q16850,Q9UBM7	Processes and pathways	GO Biological process	msigdb_gobp	99,5,105,76,49,46,83,88,27,28,95,63	46,2315,2241,210,83,2818,3043,694,2872,88,532,367,2876,2593,935,130,2336,2727,1401,99,2007,3355,2406,1496,2927,1151,76,49,3266,589,3214,28,2098,105,95,5,27,63,1455,2300	2.8943684331092254,-0.38449929077288447,-0.33934491131952355,1.2109881782657737,2.3477816274627044,-0.7580513366787757,-1.0035370570387363,0.5019846818620551,-0.8063746087452964,2.2574227850195774,0.619171741197861,0.8099100211162025,-0.8063746087452964,-0.5684611504154431,0.342355682402477,1.6887973998936312,-0.38449929077288447,-0.6625285072121776,0.09521457913715693,2.041867375489916,-0.2058028271615026,-2.800617632892994,-0.42998258634220327,0.05307774962454346,-0.8550813717441338,0.2199786322467286,2.4369781355796594,2.8943684331092254,-1.4697807385854578,0.580344223839915,-1.3109065691871442,3.7046073923024947,-0.25000179333226685,1.9790170949571289,2.1041468018137355,5.895453047698817,3.7292869846617753,2.669400494336479,0.09521457913715693,-0.33934491131952355	3367
Dysmetria	11	52	2.5118135112753723	0.0120112543411599	Q6DKK2,Q10713,P42356,P41440,O14773,Q9NPL8,Q8IV08,P07384,O75503,O60313,Q12768	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	97,287,198,102,20,87,151,240,24,209,127	2233,20,1202,1293,1979,209,2447,1813,24,240,862,1218,1315,2254,393,102,198,1995,2178,1405,1837,287,2788,127,3265,945,3284,542,2482,97,1772,1338,151,1165,2282,659,2981,1094,1437,2132,1790,87,1366,3107,2143,774,2640,514,3270,1195,302,1289	-0.33934491131952355,3.9953969719732,0.1786609951774037,0.13707430384263497,-0.2058028271615026,1.2109881782657737,-0.4758002447614249,-0.11832544439901459,3.8514472696790003,1.103996441331084,0.38263514328382814,0.1786609951774037,0.13707430384263497,-0.33934491131952355,0.7722057037721174,2.0105143282367153,1.2813706494606423,-0.2058028271615026,-0.29451413807445087,0.09521457913715693,-0.11832544439901459,0.995247055805408,-0.7101048204413503,1.7216629695769743,-1.4697807385854578,0.342355682402477,-1.5776059098511652,0.619171741197861,-0.4758002447614249,2.0730777150539357,-0.07503752950409251,0.13707430384263497,1.5557134250916398,0.2199786322467286,-0.33934491131952355,0.5412829355853829,-0.9041772408267448,0.26103110464403734,0.09521457913715693,-0.25000179333226685,-0.07503752950409251,2.3177928418789855,0.13707430384263497,-1.053799466605388,-0.25000179333226685,0.46244619964697814,-0.5684611504154431,0.657768615715268,-1.4697807385854578,0.2199786322467286,0.9585953053509725,0.1786609951774037	3367
Sphingolipid biosynthetic process	6	16	2.5046702585659	0.012256559929711	O95470,Q96G23,Q06136,Q99805,Q13510,P04062	Processes and pathways	GO Biological process	msigdb_gobp	160,38,11,184,90,210	282,1204,160,210,924,1899,1410,11,1496,90,1335,38,184,561,851,1708	0.995247055805408,0.1786609951774037,1.4881728202808266,1.2109881782657737,0.342355682402477,-0.1619123131620609,0.09521457913715693,4.783524978682848,0.05307774962454346,2.227038925427992,0.13707430384263497,3.192469446149936,1.3510176219205223,0.619171741197861,0.42266415546022,-0.032043988936474706	3367
Secondary alcohol metabolic process	12	43	2.499878540694135	0.0124235892484887	P61916,Q8WTV0,Q15800,Q14739,Q14849,O15118,P05067,P34913,Q9BQE5,Q15392,Q16850,Q9UBM7	Processes and pathways	GO Biological process	msigdb_gobp	99,5,105,76,49,46,83,88,27,28,95,63	46,1640,3329,2315,2241,210,83,2818,3043,694,2872,88,532,367,2593,935,3154,130,2880,2336,2727,1401,99,2007,3355,2406,1496,2927,1151,76,49,3266,589,3214,28,2098,105,95,5,1864,27,63,1455	2.8943684331092254,-0.032043988936474706,-1.9669363010637892,-0.38449929077288447,-0.33934491131952355,1.2109881782657737,2.3477816274627044,-0.7580513366787757,-1.0035370570387363,0.5019846818620551,-0.8063746087452964,2.2574227850195774,0.619171741197861,0.8099100211162025,-0.5684611504154431,0.342355682402477,-1.1554855115344582,1.6887973998936312,-0.8063746087452964,-0.38449929077288447,-0.6625285072121776,0.09521457913715693,2.041867375489916,-0.2058028271615026,-2.800617632892994,-0.42998258634220327,0.05307774962454346,-0.8550813717441338,0.2199786322467286,2.4369781355796594,2.8943684331092254,-1.4697807385854578,0.580344223839915,-1.3109065691871442,3.7046073923024947,-0.25000179333226685,1.9790170949571289,2.1041468018137355,5.895453047698817,-0.11832544439901459,3.7292869846617753,2.669400494336479,0.09521457913715693	3367
Organophosphate ester transmembrane transporter activity	6	11	2.4927488801289424	0.0126758460350853	P41440,Q8TB61,Q9BSK2,Q99808,Q9H2D1,Q9HC21	Functions	GO Molecular function	msigdb_gomf	102,270,274,158,123,360	1639,1001,1310,419,102,2019,270,158,274,123,360	-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706	3367
Nucleotide transmembrane transporter activity	6	11	2.4927488801289424	0.0126758460350853	P41440,Q8TB61,Q9BSK2,Q99808,Q9H2D1,Q9HC21	Functions	GO Molecular function	msigdb_gomf	102,270,274,158,123,360	1639,1001,1310,419,102,2019,270,158,274,123,360	-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706	3367
Nucleotide transport	6	11	2.4927488801289424	0.0126758460350853	P41440,Q8TB61,Q9BSK2,Q99808,Q9H2D1,Q9HC21	Processes and pathways	GO Biological process	msigdb_gobp	102,270,274,158,123,360	1639,1001,1310,419,102,2019,270,158,274,123,360	-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706	3367
Outer membrane	30	83	2.488830947758797	0.0128163891226951	Q96TC7,Q6NUM9,Q8WXH0,Q86UT6,Q8WY22,Q13505,Q9NXE4,Q9NS69,Q9BVC6,Q99720,Q99536,O43169,Q9Y6C9,P09601,P33121,Q9NQZ5,Q9UBM7,O96008,P21796,Q96RL7,Q9BUR5,Q9NZJ7,O75431,P42345,O60313,P50402,Q9NVH0,Q9Y512,Q92667,P45880	Localization	GO Cellular component	msigdb_gocc	406,493,404,496,138,18,561,26,432,36,164,283,167,40,530,323,63,308,309,339,203,222,443,448,209,578,510,521,500,115	1201,1635,2763,283,209,1296,1892,443,1719,1129,308,2241,3039,1216,40,1311,309,1061,530,2666,448,802,115,578,579,939,2400,2885,2411,18,1245,3131,650,1335,1676,1509,493,2558,1339,3133,1254,496,1085,1856,880,1165,713,2199,1345,1167,404,138,500,1604,339,406,164,2750,36,2132,203,432,1950,1529,1274,2435,2807,323,26,510,726,1111,1186,1045,1877,561,222,63,1284,1372,3145,521,167	0.1786609951774037,-0.032043988936474706,-0.7101048204413503,0.995247055805408,1.2109881782657737,0.13707430384263497,-0.1619123131620609,0.6961379107980552,-0.07503752950409251,0.2199786322467286,0.9217383587835264,-0.33934491131952355,-1.0035370570387363,0.1786609951774037,3.1123997852653797,0.13707430384263497,0.9217383587835264,0.26103110464403734,0.619171741197861,-0.6153160198205229,0.6961379107980552,0.42266415546022,1.8515558846925475,0.580344223839915,0.580344223839915,0.342355682402477,-0.42998258634220327,-0.8063746087452964,-0.42998258634220327,4.183049042361933,0.1786609951774037,-1.1044492003404638,0.5412829355853829,0.13707430384263497,-0.032043988936474706,0.05307774962454346,0.657768615715268,-0.5219578544209845,0.13707430384263497,-1.1044492003404638,0.1786609951774037,0.657768615715268,0.26103110464403734,-0.11832544439901459,0.38263514328382814,0.2199786322467286,0.5019846818620551,-0.29451413807445087,0.13707430384263497,0.2199786322467286,0.7722057037721174,1.6225833456176855,0.657768615715268,0.010659648604851009,0.884673610049861,0.7722057037721174,1.4541462370669627,-0.6625285072121776,3.218961116049131,-0.25000179333226685,1.246272443990728,0.7342826270023676,-0.1619123131620609,0.05307774962454346,0.1786609951774037,-0.42998258634220327,-0.7101048204413503,0.9217383587835264,3.802828202328214,0.657768615715268,0.5019846818620551,0.26103110464403734,0.2199786322467286,0.30182221516229196,-0.11832544439901459,0.619171741197861,1.2109881782657737,2.669400494336479,0.1786609951774037,0.13707430384263497,-1.1044492003404638,0.657768615715268,1.4541462370669627	3367
Lipid homeostasis	8	23	2.477059430715978	0.0132469841964211	Q5BJF2,P61916,Q8WTV0,Q9Y6C9,O15260,O15118,P34913,O15254	Processes and pathways	GO Biological process	msigdb_gobp	3,99,5,167,14,46,88,155	2054,46,155,14,1381,2913,2166,88,532,99,3175,1496,1926,3,821,1160,5,2897,1950,221,1455,2811,167	-0.25000179333226685,2.8943684331092254,1.522027904662708,4.34342738654226,0.09521457913715693,-0.8550813717441338,-0.29451413807445087,2.2574227850195774,0.619171741197861,2.041867375489916,-1.206907661975204,0.05307774962454346,-0.1619123131620609,6.150206234863874,0.42266415546022,0.2199786322467286,5.895453047698817,-0.8063746087452964,-0.1619123131620609,1.2109881782657737,0.09521457913715693,-0.7101048204413503,1.4541462370669627	3367
Membrane lipid biosynthetic process	9	22	2.46952428084392	0.0135292836648881	O95470,Q8NBX0,O15269,Q96G23,Q06136,Q9H490,Q99805,Q13510,P04062	Processes and pathways	GO Biological process	msigdb_gobp	160,230,282,38,11,235,184,90,210	282,1204,1812,160,210,924,1899,1410,11,1496,90,1335,230,1601,718,38,380,184,235,561,851,1708	0.995247055805408,0.1786609951774037,-0.11832544439901459,1.4881728202808266,1.2109881782657737,0.342355682402477,-0.1619123131620609,0.09521457913715693,4.783524978682848,0.05307774962454346,2.227038925427992,0.13707430384263497,1.1755156156311373,0.010659648604851009,0.5019846818620551,3.192469446149936,0.8099100211162025,1.3510176219205223,1.1398524773123389,0.619171741197861,0.42266415546022,-0.032043988936474706	3367
Sphingolipid metabolism	6	11	2.4619402016745187	0.0138187704248124	O95470,P06280,P16278,Q06136,Q13510,P04062	Processes and pathways	KEGG Pathways	msigdb_kegg	160,67,68,11,90,210	282,1204,2814,160,210,67,633,68,11,90,561	0.995247055805408,0.1786609951774037,-0.7580513366787757,1.4881728202808266,1.2109881782657737,2.554155818031785,0.5412829355853829,2.554155818031785,4.783524978682848,2.227038925427992,0.619171741197861	3367
Nucleobase containing compound transmembrane transporter activity	7	13	2.452709257645877	0.0141784885441538	Q8TB61,P41440,L0R6Q1,Q9BSK2,Q99808,Q9H2D1,Q9HC21	Functions	GO Molecular function	msigdb_gomf	270,102,251,274,158,123,360	251,1639,1001,1310,419,102,1140,2019,270,158,274,123,360	1.0679451413858796,-0.032043988936474706,0.30182221516229196,0.13707430384263497,0.7342826270023676,2.0105143282367153,0.2199786322467286,-0.2058028271615026,1.031696165695717,1.522027904662708,1.031696165695717,1.7869199137107399,0.8473984012280706	3367
Abnormality of the vasculature of the eye	17	75	2.451368933799272	0.0142314004141574	P07602,O00462,P06280,P16278,Q9Y4P3,P10619,Q14739,P01889,Q9NZ08,P17900,Q9NZJ7,P07686,P06865,P02786,P04066,Q13510,Q96DF8	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,66,67,68,302,106,76,294,148,107,222,119,84,239,94,90,290	681,66,1207,1638,1979,1640,479,1716,1300,792,2650,1721,294,239,94,527,2317,67,84,34,119,2318,106,2768,2769,68,107,797,483,1479,2164,1391,2664,1650,3233,576,1315,531,2254,3289,2590,1994,2255,1740,936,2880,2463,1228,2081,1405,1495,2406,1838,2181,1240,90,76,3284,1847,546,828,885,319,1090,969,970,2359,1349,290,2627,1876,148,222,514,302	0.5019846818620551,2.5831453876103505,0.1786609951774037,-0.032043988936474706,-0.2058028271615026,-0.032043988936474706,0.657768615715268,-0.07503752950409251,0.13707430384263497,0.42266415546022,-0.6153160198205229,-0.07503752950409251,0.9585953053509725,1.103996441331084,2.1041468018137355,0.619171741197861,-0.38449929077288447,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,-0.38449929077288447,1.9473741733456051,-0.7101048204413503,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.42266415546022,0.657768615715268,0.05307774962454346,-0.29451413807445087,0.09521457913715693,-0.6153160198205229,-0.032043988936474706,-1.3634818904670298,0.580344223839915,0.13707430384263497,0.619171741197861,-0.33934491131952355,-1.632089162713181,-0.5684611504154431,-0.2058028271615026,-0.33934491131952355,-0.07503752950409251,0.342355682402477,-0.8063746087452964,-0.4758002447614249,0.1786609951774037,-0.25000179333226685,0.09521457913715693,0.05307774962454346,-0.42998258634220327,-0.11832544439901459,-0.29451413807445087,0.1786609951774037,2.227038925427992,2.4369781355796594,-1.5776059098511652,-0.11832544439901459,0.619171741197861,0.42266415546022,0.38263514328382814,0.9217383587835264,0.26103110464403734,0.342355682402477,0.342355682402477,-0.38449929077288447,0.13707430384263497,0.995247055805408,-0.5684611504154431,-0.11832544439901459,1.5892312826899408,1.2109881782657737,0.657768615715268,0.9585953053509725	3367
Regulation of blood pressure	6	17	2.445498867156985	0.0144651903031889	P42785,Q9UIQ6,P09601,P80404,P42892,Q9HB40	Processes and pathways	GO Biological process	msigdb_gobp	2,103,40,75,12,16	3001,3003,1215,40,3042,864,2,12,2077,1829,75,1664,2937,16,148,103,2646	-0.9536627270282968,-0.9536627270282968,0.1786609951774037,3.1123997852653797,-1.0035370570387363,0.38263514328382814,6.292167445838333,4.697545811150349,-0.25000179333226685,-0.11832544439901459,2.4369781355796594,-0.032043988936474706,-0.8550813717441338,4.320727255133443,1.5892312826899408,2.0105143282367153,-0.5684611504154431	3367
Organic anion transport	12	39	2.4131268399823504	0.0158163143467868	Q9H2D1,P07602,P28288,P41440,P80404,Q9UBX3,P30825,Q9NZJ7,O60831,Q8TB61,Q9HC21,Q99808	Processes and pathways	GO Biological process	msigdb_gobp	123,34,197,102,75,142,201,222,362,270,360,158	1889,1639,362,630,2450,1304,2316,1001,2064,34,2384,1556,1310,419,1647,197,201,102,1141,807,2781,75,1495,1496,2188,2346,1584,2019,1250,270,158,123,2218,1872,360,222,142,2300,1285	-0.1619123131620609,-0.032043988936474706,0.8099100211162025,0.5412829355853829,-0.4758002447614249,0.13707430384263497,-0.38449929077288447,0.30182221516229196,-0.25000179333226685,3.297852942116772,-0.42998258634220327,0.010659648604851009,0.13707430384263497,0.7342826270023676,-0.032043988936474706,1.2813706494606423,1.246272443990728,2.0105143282367153,0.2199786322467286,0.42266415546022,-0.7101048204413503,2.4369781355796594,0.05307774962454346,0.05307774962454346,-0.29451413807445087,-0.38449929077288447,0.010659648604851009,-0.2058028271615026,0.1786609951774037,1.031696165695717,1.522027904662708,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.2109881782657737,1.6225833456176855,-0.33934491131952355,0.1786609951774037	3367
Molecular transducer activity	7	30	2.402000763822557	0.0163056743844636	Q14108,Q99720,Q8WTV0,P20645,O15118,Q5KU26,Q15629	Functions	GO Molecular function	msigdb_gomf	32,36,5,44,46,120,60	786,524,46,1808,1209,2064,156,44,1061,867,2169,1740,3193,1324,2183,32,60,1584,2102,120,2796,5,972,841,36,407,511,1282,1454,2376	0.42266415546022,0.619171741197861,2.8943684331092254,-0.11832544439901459,0.1786609951774037,-0.25000179333226685,1.522027904662708,2.976917059317765,0.26103110464403734,0.38263514328382814,-0.29451413807445087,-0.07503752950409251,-1.2587149217723634,0.13707430384263497,-0.29451413807445087,3.5799366048175845,2.6979179668449453,0.010659648604851009,-0.25000179333226685,1.8193146884450921,-0.7101048204413503,5.895453047698817,0.342355682402477,0.42266415546022,3.218961116049131,0.7722057037721174,0.657768615715268,0.1786609951774037,0.09521457913715693,-0.38449929077288447	3367
Basal part of cell	16	47	2.3937696281103005	0.0166762192864309	P42785,P19022,Q9NWH9,P41440,Q14254,O00159,P35222,P30825,Q15043,Q12846,P02786,O75955,Q6P4Q7,O94832,Q99808,Q03001	Localization	GO Cellular component	msigdb_gocc	2,346,511,102,369,522,531,201,315,144,239,238,460,365,158,191	522,1052,1292,3271,238,365,239,2316,1215,2159,2384,2711,1556,1308,2068,2323,2247,346,864,1393,201,531,635,102,2,807,740,2781,1488,191,538,1324,144,1071,873,747,1578,369,315,1584,460,1590,2119,1354,1949,158,511	0.619171741197861,0.26103110464403734,0.13707430384263497,-1.523502876429464,1.103996441331084,0.8099100211162025,1.103996441331084,-0.38449929077288447,0.1786609951774037,-0.29451413807445087,-0.42998258634220327,-0.6625285072121776,0.010659648604851009,0.13707430384263497,-0.25000179333226685,-0.38449929077288447,-0.33934491131952355,0.8473984012280706,0.38263514328382814,0.09521457913715693,1.246272443990728,0.619171741197861,0.5412829355853829,2.0105143282367153,6.292167445838333,0.42266415546022,0.46244619964697814,-0.7101048204413503,0.05307774962454346,1.3162849902600815,0.619171741197861,0.13707430384263497,1.5892312826899408,0.26103110464403734,0.38263514328382814,0.46244619964697814,0.010659648604851009,0.8099100211162025,0.9217383587835264,0.010659648604851009,0.6961379107980552,0.010659648604851009,-0.25000179333226685,0.13707430384263497,-0.1619123131620609,1.522027904662708,0.657768615715268	3367
Abnormality of corneal stroma	7	17	2.3907746868432627	0.0168128671495728	P16278,P10619,Q16625,O43933,P34913,Q13510,O43505	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	68,106,168,15,88,90,122	122,15,210,106,68,797,483,88,1006,1568,2181,90,168,1935,970,615,2858	1.7869199137107399,4.320727255133443,1.2109881782657737,1.9473741733456051,2.554155818031785,0.42266415546022,0.657768615715268,2.2574227850195774,0.30182221516229196,0.010659648604851009,-0.29451413807445087,2.227038925427992,1.419946185566603,-0.1619123131620609,0.342355682402477,0.580344223839915,-0.7580513366787757	3367
Negative regulation of dna replication	7	11	2.3897104854733646	0.0168616587887011	P31949,Q7Z5K2,Q9NZC9,Q9BZE4,P54132,Q9UNS1,Q99741	Processes and pathways	GO Biological process	msigdb_gobp	101,427,615,556,536,117,666	1555,101,1487,536,708,427,1591,666,556,615,117	0.010659648604851009,2.0105143282367153,0.05307774962454346,0.619171741197861,0.5019846818620551,0.7342826270023676,0.010659648604851009,0.5412829355853829,0.619171741197861,0.580344223839915,1.8515558846925475	3367
Abnormality of the autonomic nervous system	17	65	2.38557017542078	0.0170526685985328	Q10713,P07602,P06280,Q9UJX6,O15269,P41440,P42892,Q96RL7,Q9NZJ7,Q99996,Q96EK5,P07686,P04062,O15360,O76024,Q9UBM7,Q8N3U4	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	287,34,67,134,282,102,12,339,222,116,321,119,210,121,364,63,289	1202,282,1204,121,2814,997,479,688,364,2156,210,67,34,119,633,1218,1391,393,3289,637,3048,102,12,934,3049,1829,2081,3015,1919,1837,287,2839,1153,1926,1415,545,1338,1159,2484,3133,289,2199,969,970,2359,321,2621,837,1608,339,721,3304,116,768,1443,2627,1870,1874,1621,222,63,134,1373,2994,1804	0.1786609951774037,0.995247055805408,0.1786609951774037,1.7869199137107399,-0.7580513366787757,0.30182221516229196,0.657768615715268,0.5019846818620551,0.8099100211162025,-0.29451413807445087,1.2109881782657737,2.554155818031785,3.297852942116772,1.8193146884450921,0.5412829355853829,0.1786609951774037,0.09521457913715693,0.7722057037721174,-1.632089162713181,0.5412829355853829,-1.0035370570387363,2.0105143282367153,4.697545811150349,0.342355682402477,-1.0035370570387363,-0.11832544439901459,-0.25000179333226685,-0.9536627270282968,-0.1619123131620609,-0.11832544439901459,0.995247055805408,-0.7580513366787757,0.2199786322467286,-0.1619123131620609,0.09521457913715693,0.619171741197861,0.13707430384263497,0.2199786322467286,-0.4758002447614249,-1.1044492003404638,0.995247055805408,-0.29451413807445087,0.342355682402477,0.342355682402477,-0.38449929077288447,0.9217383587835264,-0.5684611504154431,0.42266415546022,0.010659648604851009,0.884673610049861,0.5019846818620551,-1.7421936575233459,1.8515558846925475,0.46244619964697814,0.09521457913715693,-0.5684611504154431,-0.11832544439901459,-0.11832544439901459,0.010659648604851009,1.2109881782657737,2.669400494336479,1.6557714498436458,0.13707430384263497,-0.9041772408267448,-0.07503752950409251	3367
Glycosylation	16	45	2.3698016406873355	0.017797630798503	O60502,Q86SF2,Q9UP83,Q10471,Q2TAA5,Q6ZXV5,Q16706,O60476,O15118,Q9H0U3,P46977,O75503,O75352,Q08379,O43505,P04062	Processes and pathways	GO Biological process	msigdb_gobp	64,256,473,312,350,297,335,81,46,322,422,24,363,212,122,210	1548,46,2308,122,81,64,1642,1812,3325,363,24,2706,210,1983,919,2721,422,2544,2180,872,2408,212,312,452,1327,1329,335,350,297,1853,256,1776,661,1606,2125,1787,322,674,2808,1187,2144,473,2950,905,1121	0.010659648604851009,2.8943684331092254,-0.38449929077288447,1.7869199137107399,2.377641277448686,2.640766626646635,-0.032043988936474706,-0.11832544439901459,-1.9101855426565795,0.8099100211162025,3.8514472696790003,-0.6625285072121776,1.2109881782657737,-0.2058028271615026,0.342355682402477,-0.6625285072121776,0.7342826270023676,-0.5219578544209845,-0.29451413807445087,0.38263514328382814,-0.42998258634220327,1.2109881782657737,0.9217383587835264,0.6961379107980552,0.13707430384263497,0.13707430384263497,0.884673610049861,0.8473984012280706,0.9585953053509725,-0.11832544439901459,1.0679451413858796,-0.07503752950409251,0.5412829355853829,0.010659648604851009,-0.25000179333226685,-0.07503752950409251,0.9217383587835264,0.5412829355853829,-0.7101048204413503,0.2199786322467286,-0.25000179333226685,0.6961379107980552,-0.8550813717441338,0.38263514328382814,0.26103110464403734	3367
Ion transmembrane transporter activity	26	80	2.365231914978441	0.0180187834667937	Q70HW3,Q9UBX3,Q8TB61,Q99808,Q9BVC6,O43772,P12236,Q15043,Q9H0U3,Q9Y487,Q9HD20,Q9C0H2,Q6P4Q7,Q93050,P21796,P47985,P30825,O75964,P16615,Q9HC21,P41440,P13073,Q13423,Q9UI12,P45880,Q9H2D1	Functions	GO Molecular function	msigdb_gomf	13,142,270,158,432,42,419,315,322,186,185,56,460,62,309,449,201,89,211,360,102,232,233,249,115,123	2305,1889,2814,42,1639,630,2865,89,690,1304,693,1215,1001,1896,2159,2710,2384,529,3338,1385,1556,1310,419,232,211,864,2249,1732,2871,309,1562,1989,201,1394,2719,2875,2591,102,115,449,3332,641,1141,807,2781,645,2401,1011,871,1069,1495,233,3276,315,1584,594,2019,1250,460,13,1683,270,972,62,158,432,56,322,123,2218,1872,360,185,142,512,249,1285,1372,186,1376	-0.38449929077288447,-0.1619123131620609,-0.7580513366787757,3.0585160335120065,-0.032043988936474706,0.5412829355853829,-0.8063746087452964,2.227038925427992,0.5019846818620551,0.13707430384263497,0.5019846818620551,0.1786609951774037,0.30182221516229196,-0.1619123131620609,-0.29451413807445087,-0.6625285072121776,-0.42998258634220327,0.619171741197861,-2.197689911987167,0.09521457913715693,0.010659648604851009,0.13707430384263497,0.7342826270023676,1.1398524773123389,1.2109881782657737,0.38263514328382814,-0.33934491131952355,-0.07503752950409251,-0.8063746087452964,0.9217383587835264,0.010659648604851009,-0.2058028271615026,1.246272443990728,0.09521457913715693,-0.6625285072121776,-0.8063746087452964,-0.5684611504154431,2.0105143282367153,1.8515558846925475,0.6961379107980552,-2.024062737158297,0.5412829355853829,0.2199786322467286,0.42266415546022,-0.7101048204413503,0.5412829355853829,-0.42998258634220327,0.30182221516229196,0.38263514328382814,0.26103110464403734,0.05307774962454346,1.1398524773123389,-1.523502876429464,0.9217383587835264,0.010659648604851009,0.580344223839915,-0.2058028271615026,0.1786609951774037,0.6961379107980552,4.433541950109594,-0.032043988936474706,1.031696165695717,0.342355682402477,2.669400494336479,1.522027904662708,0.7342826270023676,2.782782542710472,0.9217383587835264,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.3510176219205223,1.6225833456176855,0.657768615715268,1.103996441331084,0.1786609951774037,0.13707430384263497,1.3510176219205223,0.13707430384263497	3367
Endopeptidase activity	15	64	2.345582030411038	0.0189973977286432	Q8TCT9,Q10713,P67812,Q70CQ2,P42892,Q9NZ08,Q99538,O75844,O14773,Q4J6C6,P49721,Q92542,P07384,P60900,Q2T9J0	Functions	GO Molecular function	msigdb_gomf	354,287,285,298,12,148,177,113,20,268,22,218,240,242,157	20,1469,1813,113,2158,240,2659,2068,1730,798,1820,2663,1650,485,2455,2326,1652,1062,1137,2780,12,2877,3261,2879,22,2882,580,869,3282,242,285,287,453,1241,2613,371,157,268,542,2479,2106,298,1025,1169,354,218,1601,2120,971,1032,1352,2849,1437,2209,177,2804,1699,148,2372,1188,1117,731,2052,1289	3.9953969719732,0.05307774962454346,-0.11832544439901459,1.8515558846925475,-0.29451413807445087,1.103996441331084,-0.6153160198205229,-0.25000179333226685,-0.07503752950409251,0.42266415546022,-0.11832544439901459,-0.6153160198205229,-0.032043988936474706,0.657768615715268,-0.4758002447614249,-0.38449929077288447,-0.032043988936474706,0.26103110464403734,0.2199786322467286,-0.7101048204413503,4.697545811150349,-0.8063746087452964,-1.4697807385854578,-0.8063746087452964,3.8997452806748156,-0.8063746087452964,0.580344223839915,0.38263514328382814,-1.5776059098511652,1.103996441331084,0.995247055805408,0.995247055805408,0.6961379107980552,0.1786609951774037,-0.5684611504154431,0.8099100211162025,1.522027904662708,1.031696165695717,0.619171741197861,-0.4758002447614249,-0.25000179333226685,0.9585953053509725,0.30182221516229196,0.2199786322467286,0.8473984012280706,1.2109881782657737,0.010659648604851009,-0.25000179333226685,0.342355682402477,0.30182221516229196,0.13707430384263497,-0.7580513366787757,0.09521457913715693,-0.29451413807445087,1.3855706609057188,-0.7101048204413503,-0.032043988936474706,1.5892312826899408,-0.38449929077288447,0.2199786322467286,0.26103110464403734,0.5019846818620551,-0.2058028271615026,0.1786609951774037	3367
SLC25 family of mitochondrial transporters	8	19	2.3409697712079858	0.0192337243261373	Q9Y6C9,O43772,Q70HW3,Q9UBX3,Q9BSK2,Q9NZJ7,Q9H2D1,Q9HC21	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	167,42,13,142,274,222,123,360	42,1639,630,1001,1310,419,1141,1069,1495,2019,13,274,123,2218,360,222,142,1285,167	3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.30182221516229196,0.13707430384263497,0.7342826270023676,0.2199786322467286,0.26103110464403734,0.05307774962454346,-0.2058028271615026,4.433541950109594,1.031696165695717,1.7869199137107399,-0.29451413807445087,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627	3367
Mitochondrial carrier domain superfamily [IPR023395]	8	19	2.3409697712079858	0.0192337243261373	Q9Y6C9,O43772,Q70HW3,Q9UBX3,Q9BSK2,Q9NZJ7,Q9H2D1,Q9HC21	Sequence	InterPro Superfamily	interpro_homologous_superfamily	167,42,13,142,274,222,123,360	42,1639,630,1001,1310,419,1141,1069,1495,2019,13,274,123,2218,360,222,142,1285,167	3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.30182221516229196,0.13707430384263497,0.7342826270023676,0.2199786322467286,0.26103110464403734,0.05307774962454346,-0.2058028271615026,4.433541950109594,1.031696165695717,1.7869199137107399,-0.29451413807445087,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627	3367
Mitochondrial substrate/solute carrier [IPR018108]	8	19	2.3409697712079858	0.0192337243261373	Q9Y6C9,O43772,Q70HW3,Q9UBX3,Q9BSK2,Q9NZJ7,Q9H2D1,Q9HC21	Sequence	InterPro Repeat	interpro_repeat	167,42,13,142,274,222,123,360	42,1639,630,1001,1310,419,1141,1069,1495,2019,13,274,123,2218,360,222,142,1285,167	3.0585160335120065,-0.032043988936474706,0.5412829355853829,0.30182221516229196,0.13707430384263497,0.7342826270023676,0.2199786322467286,0.26103110464403734,0.05307774962454346,-0.2058028271615026,4.433541950109594,1.031696165695717,1.7869199137107399,-0.29451413807445087,0.8473984012280706,1.2109881782657737,1.6225833456176855,0.1786609951774037,1.4541462370669627	3367
Glycerolipid biosynthetic process	12	47	2.33350106042626	0.0196218627359128	Q92604,Q8NCC3,Q10713,P42356,Q96Q15,Q8WTV0,Q96N66,Q9H490,P35790,O95674,Q86TV6,Q9UG56	Processes and pathways	GO Biological process	msigdb_gobp	259,0,287,198,98,5,133,235,48,330,182,361	570,1975,624,2702,1812,1129,330,3230,2956,1730,3189,530,48,198,738,1571,287,1073,1663,1156,426,182,1774,0,883,2202,5,3069,758,259,1601,718,2122,133,98,380,3321,975,2032,1099,1951,1359,235,2696,1706,361,566	0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.11832544439901459,0.2199786322467286,0.884673610049861,-1.3634818904670298,-0.9041772408267448,-0.07503752950409251,-1.2587149217723634,0.619171741197861,2.8943684331092254,1.2813706494606423,0.46244619964697814,0.010659648604851009,0.995247055805408,0.26103110464403734,-0.032043988936474706,0.2199786322467286,0.7342826270023676,1.3510176219205223,-0.07503752950409251,6.753408671655479,0.38263514328382814,-0.29451413807445087,5.895453047698817,-1.0035370570387363,0.46244619964697814,1.0679451413858796,0.010659648604851009,0.5019846818620551,-0.25000179333226685,1.6557714498436458,2.0730777150539357,0.8099100211162025,-1.853811091154964,0.342355682402477,-0.2058028271615026,0.26103110464403734,-0.1619123131620609,0.13707430384263497,1.1398524773123389,-0.6153160198205229,-0.032043988936474706,0.8473984012280706,0.619171741197861	3367
Myoclonic seizure	9	56	2.3178756819966044	0.0204560784269198	P07602,P16278,Q9UJX6,Q96N66,Q9NZJ7,P07686,O75503,Q13510,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,68,134,133,222,119,24,90,210	1635,1465,2953,2512,628,2863,1812,24,1720,210,34,119,1556,68,2164,576,867,1484,1485,3309,1829,2080,3124,1404,1232,1494,2785,2610,2788,90,1761,2792,1153,954,1509,1338,1681,1516,718,2747,761,973,837,133,2035,1443,2693,2218,724,222,1961,134,326,2441,1195,1289	-0.032043988936474706,0.05307774962454346,-0.9041772408267448,-0.5219578544209845,0.5412829355853829,-0.8063746087452964,-0.11832544439901459,3.8514472696790003,-0.07503752950409251,1.2109881782657737,3.297852942116772,1.8193146884450921,0.010659648604851009,2.554155818031785,-0.29451413807445087,0.580344223839915,0.38263514328382814,0.05307774962454346,0.05307774962454346,-1.7978135821100152,-0.11832544439901459,-0.25000179333226685,-1.1044492003404638,0.09521457913715693,0.1786609951774037,0.05307774962454346,-0.7101048204413503,-0.5684611504154431,-0.7101048204413503,2.227038925427992,-0.07503752950409251,-0.7101048204413503,0.2199786322467286,0.342355682402477,0.05307774962454346,0.13707430384263497,-0.032043988936474706,0.05307774962454346,0.5019846818620551,-0.6625285072121776,0.46244619964697814,0.342355682402477,0.42266415546022,1.6557714498436458,-0.2058028271615026,0.09521457913715693,-0.6153160198205229,-0.29451413807445087,0.5019846818620551,1.2109881782657737,-0.1619123131620609,1.6557714498436458,0.9217383587835264,-0.42998258634220327,0.2199786322467286,0.1786609951774037	3367
Receptor	9	28	2.296020230170063	0.0216747246975099	Q14108,Q8WTV0,Q567V2,Q9NR77,P20645,Q9UQB8,Q9HCD5,A6NIH7,P11717	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	32,5,72,278,44,45,383,57,156	57,1637,1295,1891,2448,631,918,2064,156,44,2169,454,32,747,1583,72,2106,2796,1160,5,2027,407,1110,383,278,1047,1192,45	2.754607952931739,-0.032043988936474706,0.13707430384263497,-0.1619123131620609,-0.4758002447614249,0.5412829355853829,0.342355682402477,-0.25000179333226685,1.522027904662708,2.976917059317765,-0.29451413807445087,0.6961379107980552,3.5799366048175845,0.46244619964697814,0.010659648604851009,2.4958131623722344,-0.25000179333226685,-0.7101048204413503,0.2199786322467286,5.895453047698817,-0.2058028271615026,0.7722057037721174,0.26103110464403734,0.8099100211162025,1.031696165695717,0.30182221516229196,0.2199786322467286,2.9495075939089457	3367
Nuclear membrane	25	64	2.287973013229919	0.0221390927505416	Q8WXH0,Q9UH99,Q9BZE4,Q9H1E5,Q8WUM0,O15260,Q9NXE4,P12270,Q149N8,Q9BVC6,P57740,P67812,Q9BTX1,Q96G23,O75694,Q9Y5Q9,O75976,O00560,Q8IY37,Q8WYP5,Q9NXW2,Q14739,A2RRP1,P50402,O75179	Localization	Protein Atlas Subcellular	protein_atlas_subcellular_location_all	404,280,556,276,552,14,561,392,649,432,646,285,165,38,526,439,175,188,599,465,204,76,569,578,480	569,188,1975,1637,14,1467,480,526,175,1894,1722,3205,2767,392,2528,1218,2395,1903,739,804,578,645,646,285,812,76,1665,649,2932,2552,1506,1158,2112,1855,1593,599,1171,2894,552,404,465,38,2030,764,2804,1439,2898,165,432,2429,556,276,1791,1874,561,204,280,2856,2641,2576,3080,1969,1374,439	0.580344223839915,1.3162849902600815,-0.2058028271615026,-0.032043988936474706,4.34342738654226,0.05307774962454346,0.657768615715268,0.619171741197861,1.3855706609057188,-0.1619123131620609,-0.07503752950409251,-1.3109065691871442,-0.7101048204413503,0.7722057037721174,-0.5219578544209845,0.1786609951774037,-0.42998258634220327,-0.1619123131620609,0.46244619964697814,0.42266415546022,0.580344223839915,0.5412829355853829,0.5412829355853829,0.995247055805408,0.42266415546022,2.4369781355796594,-0.032043988936474706,0.5412829355853829,-0.8550813717441338,-0.5219578544209845,0.05307774962454346,0.2199786322467286,-0.25000179333226685,-0.11832544439901459,0.010659648604851009,0.580344223839915,0.2199786322467286,-0.8063746087452964,0.619171741197861,0.7722057037721174,0.6961379107980552,3.192469446149936,-0.2058028271615026,0.46244619964697814,-0.7101048204413503,0.09521457913715693,-0.8063746087452964,1.4541462370669627,0.7342826270023676,-0.42998258634220327,0.619171741197861,1.031696165695717,-0.07503752950409251,-0.11832544439901459,0.619171741197861,1.246272443990728,1.031696165695717,-0.7580513366787757,-0.5684611504154431,-0.5219578544209845,-1.0035370570387363,-0.1619123131620609,0.13707430384263497,0.7342826270023676	3367
Translocation	25	47	2.276335589585388	0.0228259315540144	P49790,P61619,P35658,O14925,Q8WUM0,Q9NS69,P12270,P57740,Q9UBU9,Q9BTX1,O75694,O00159,Q99442,Q99595,Q15629,Q8WYP5,P49792,Q92621,Q9Y5L4,P52948,Q99567,O60830,Q12769,Q8N1F7,P60059	Processes and pathways	Protein Atlas Biological process	protein_atlas_biological_process	739,871,636,623,552,26,392,646,852,165,526,522,841,178,60,465,804,338,223,806,765,96,584,882,241	522,623,996,96,2448,526,392,636,2395,739,804,806,870,646,241,1747,871,2885,3158,584,60,1077,1770,1771,1589,882,2284,1170,1171,1858,1425,552,465,338,1523,841,765,178,165,2626,1357,1874,26,1282,852,2576,223	0.619171741197861,0.5412829355853829,0.30182221516229196,2.0730777150539357,-0.4758002447614249,0.619171741197861,0.7722057037721174,0.5412829355853829,-0.42998258634220327,0.46244619964697814,0.42266415546022,0.42266415546022,0.38263514328382814,0.5412829355853829,1.103996441331084,-0.07503752950409251,0.38263514328382814,-0.8063746087452964,-1.1554855115344582,0.580344223839915,2.6979179668449453,0.26103110464403734,-0.07503752950409251,-0.07503752950409251,0.010659648604851009,0.38263514328382814,-0.33934491131952355,0.2199786322467286,0.2199786322467286,-0.11832544439901459,0.09521457913715693,0.619171741197861,0.6961379107980552,0.884673610049861,0.05307774962454346,0.42266415546022,0.46244619964697814,1.3855706609057188,1.4541462370669627,-0.5684611504154431,0.13707430384263497,-0.11832544439901459,3.802828202328214,0.1786609951774037,0.42266415546022,-0.5219578544209845,1.2109881782657737	3367
Retinal degeneration	19	56	2.2726916884225803	0.0230447658806249	O14773,O75648,P42858,O75503,P50897,Q6P2Q9,Q10713,P04439,Q8IY17,Q96F07,P51648,Q14191,Q13510,O00754,P04062,O60313,Q9UG56,Q7LGA3,P19447	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	20,389,265,24,29,546,287,527,316,199,333,215,90,208,210,209,361,374,483	2761,208,20,1207,209,2383,24,792,389,1726,1816,210,527,1476,797,1311,483,1479,1821,2664,531,2591,265,2723,2880,29,333,3014,2781,3157,1146,1232,2785,2610,287,1411,90,215,1152,546,374,655,316,2976,1424,885,1090,199,2127,2210,2624,2627,361,3270,2507,3299	-0.7101048204413503,1.2109881782657737,3.9953969719732,0.1786609951774037,1.2109881782657737,-0.42998258634220327,3.8514472696790003,0.42266415546022,0.7722057037721174,-0.07503752950409251,-0.11832544439901459,1.2109881782657737,0.619171741197861,0.05307774962454346,0.42266415546022,0.13707430384263497,0.657768615715268,0.05307774962454346,-0.11832544439901459,-0.6153160198205229,0.619171741197861,-0.5684611504154431,1.031696165695717,-0.6625285072121776,-0.8063746087452964,3.679843814797915,0.884673610049861,-0.9536627270282968,-0.7101048204413503,-1.1554855115344582,0.2199786322467286,0.1786609951774037,-0.7101048204413503,-0.5684611504154431,0.995247055805408,0.09521457913715693,2.227038925427992,1.2109881782657737,0.2199786322467286,0.619171741197861,0.8099100211162025,0.5412829355853829,0.9217383587835264,-0.9041772408267448,0.09521457913715693,0.38263514328382814,0.26103110464403734,1.2813706494606423,-0.25000179333226685,-0.29451413807445087,-0.5684611504154431,-0.5684611504154431,0.8473984012280706,-1.4697807385854578,-0.4758002447614249,-1.686951965968084	3367
Mental deterioration	28	100	2.24632254192356	0.0246833557121541	P42858,O75503,Q9BQE5,P50897,Q14108,O95470,P07602,Q10713,O15118,Q9Y487,Q8IY17,Q9NQZ5,P54802,O96008,P16278,Q96F07,Q96RL7,Q9NZJ7,P05067,Q9NPL8,P06865,Q13510,P04062,O60313,P04350,P61916,P17900,P07686	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	265,24,27,29,32,160,34,287,46,186,316,323,65,308,68,199,339,222,83,87,84,90,210,209,366,99,107,119	1635,46,2814,858,209,2060,688,1300,24,364,160,308,693,210,3337,366,83,84,34,119,3207,2524,1305,1476,1058,633,68,923,107,797,1218,2164,1391,2072,865,1899,576,2168,421,2875,2591,802,265,1484,933,2723,29,2832,1829,65,1568,1745,99,3157,1232,1572,3015,1919,2785,1837,2610,287,2411,1923,945,90,32,1330,2551,877,1509,1772,824,2484,3133,316,2199,758,970,1519,199,1608,339,721,3304,2210,27,2131,87,323,900,2991,222,2143,774,3270,1373,2994,186,3299	-0.032043988936474706,2.8943684331092254,-0.7580513366787757,0.38263514328382814,1.2109881782657737,-0.25000179333226685,0.5019846818620551,0.13707430384263497,3.8514472696790003,0.8099100211162025,1.4881728202808266,0.9217383587835264,0.5019846818620551,1.2109881782657737,-2.197689911987167,0.8099100211162025,2.3477816274627044,2.3177928418789855,3.297852942116772,1.8193146884450921,-1.3109065691871442,-0.5219578544209845,0.13707430384263497,0.05307774962454346,0.26103110464403734,0.5412829355853829,2.554155818031785,0.342355682402477,1.9155840365977252,0.42266415546022,0.1786609951774037,-0.29451413807445087,0.09521457913715693,-0.25000179333226685,0.38263514328382814,-0.1619123131620609,0.580344223839915,-0.29451413807445087,0.7342826270023676,-0.8063746087452964,-0.5684611504154431,0.42266415546022,1.031696165695717,0.05307774962454346,0.342355682402477,-0.6625285072121776,3.679843814797915,-0.7580513366787757,-0.11832544439901459,2.640766626646635,0.010659648604851009,-0.07503752950409251,2.041867375489916,-1.1554855115344582,0.1786609951774037,0.010659648604851009,-0.9536627270282968,-0.1619123131620609,-0.7101048204413503,-0.11832544439901459,-0.5684611504154431,0.995247055805408,-0.42998258634220327,-0.1619123131620609,0.342355682402477,2.227038925427992,3.5799366048175845,0.13707430384263497,-0.5219578544209845,0.38263514328382814,0.05307774962454346,-0.07503752950409251,0.42266415546022,-0.4758002447614249,-1.1044492003404638,0.9217383587835264,-0.29451413807445087,0.46244619964697814,0.342355682402477,0.05307774962454346,1.2813706494606423,0.010659648604851009,0.884673610049861,0.5019846818620551,-1.7421936575233459,-0.29451413807445087,3.7292869846617753,-0.25000179333226685,2.3177928418789855,0.9217383587835264,0.38263514328382814,-0.9041772408267448,1.2109881782657737,-0.25000179333226685,0.46244619964697814,-1.4697807385854578,0.13707430384263497,-0.9041772408267448,1.3510176219205223,-1.686951965968084	3367
Protein processing	14	42	2.245812042818297	0.02471604960951	Q10713,P67812,Q96F07,Q9NQH7,P42892,O75976,Q99538,O75844,Q92896,Q92542,O75503,Q2T9J0,Q15392,Q9UG56	Processes and pathways	GO Biological process	msigdb_gobp	287,285,199,61,12,175,177,113,52,218,24,157,28,361	2308,2309,1813,24,113,175,2708,3170,3039,2159,1383,1730,3280,737,1137,2780,12,2597,2542,285,287,1070,2736,28,157,542,2479,1081,1346,354,218,52,199,2983,1437,177,2804,61,361,1964,3240,1289	-0.38449929077288447,-0.38449929077288447,-0.11832544439901459,3.8514472696790003,1.8515558846925475,1.3855706609057188,-0.6625285072121776,-1.206907661975204,-1.0035370570387363,-0.29451413807445087,0.09521457913715693,-0.07503752950409251,-1.5776059098511652,0.46244619964697814,0.2199786322467286,-0.7101048204413503,4.697545811150349,-0.5684611504154431,-0.5219578544209845,0.995247055805408,0.995247055805408,0.26103110464403734,-0.6625285072121776,3.7046073923024947,1.522027904662708,0.619171741197861,-0.4758002447614249,0.26103110464403734,0.13707430384263497,0.8473984012280706,1.2109881782657737,2.810844890271643,1.2813706494606423,-0.9041772408267448,0.09521457913715693,1.3855706609057188,-0.7101048204413503,2.6979179668449453,0.8473984012280706,-0.1619123131620609,-1.3634818904670298,0.1786609951774037	3367
Glycerolipid metabolic process	23	65	2.244133583082396	0.0248238077724354	Q92604,Q8NCC3,Q8N9F7,Q8WTV0,Q96N66,Q9NXE4,Q9Y217,Q10713,Q6IAN0,P33121,P35790,Q86TV6,Q8IY17,Q9BZF1,P42356,O95674,O00443,Q9UG56,P50416,Q96Q15,Q9H490,Q96S52,Q8N2K0	Processes and pathways	GO Biological process	msigdb_gobp	259,0,403,5,133,561,566,287,426,530,48,182,316,192,198,330,570,361,579,98,235,380,659	3200,570,1975,624,2702,1812,1129,330,3230,2956,1730,1390,3189,3247,530,48,932,198,1485,738,579,1829,1571,2786,287,1073,1663,1156,1335,426,182,1774,316,659,403,0,883,2202,5,3069,758,259,1601,718,2122,2897,133,98,380,3321,975,2750,2032,1099,1951,1359,192,1868,235,2696,1706,561,361,1964,566	-1.3109065691871442,0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.11832544439901459,0.2199786322467286,0.884673610049861,-1.3634818904670298,-0.9041772408267448,-0.07503752950409251,0.09521457913715693,-1.2587149217723634,-1.416440179685344,0.619171741197861,2.8943684331092254,0.342355682402477,1.2813706494606423,0.05307774962454346,0.46244619964697814,0.580344223839915,-0.11832544439901459,0.010659648604851009,-0.7101048204413503,0.995247055805408,0.26103110464403734,-0.032043988936474706,0.2199786322467286,0.13707430384263497,0.7342826270023676,1.3510176219205223,-0.07503752950409251,0.9217383587835264,0.5412829355853829,0.7722057037721174,6.753408671655479,0.38263514328382814,-0.29451413807445087,5.895453047698817,-1.0035370570387363,0.46244619964697814,1.0679451413858796,0.010659648604851009,0.5019846818620551,-0.25000179333226685,-0.8063746087452964,1.6557714498436458,2.0730777150539357,0.8099100211162025,-1.853811091154964,0.342355682402477,-0.6625285072121776,-0.2058028271615026,0.26103110464403734,-0.1619123131620609,0.13707430384263497,1.3162849902600815,-0.11832544439901459,1.1398524773123389,-0.6153160198205229,-0.032043988936474706,0.619171741197861,0.8473984012280706,-0.1619123131620609,0.619171741197861	3367
Abnormal epiphyseal ossification	6	17	2.23285511913038	0.0255585000684117	Q96HA7,Q14739,O43933,Q2M1P5,Q9UG56,Q9UBM7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	231,76,15,217,361,63	1200,15,1471,2448,1058,1994,394,76,1243,589,2098,217,231,1605,1606,63,361	0.1786609951774037,4.320727255133443,0.05307774962454346,-0.4758002447614249,0.26103110464403734,-0.2058028271615026,0.7722057037721174,2.4369781355796594,0.1786609951774037,0.580344223839915,-0.25000179333226685,1.2109881782657737,1.1755156156311373,0.010659648604851009,0.010659648604851009,2.669400494336479,0.8473984012280706	3367
Cholesterol binding	7	14	2.221339889623096	0.0263279490283325	Q9BZF1,Q14108,P61916,Q14849,Q9H4L5,O15118,P45880	Functions	GO Molecular function	msigdb_gomf	192,32,99,49,147,46,115	46,2315,2710,309,3121,1061,532,115,99,32,49,192,2215,147	2.8943684331092254,-0.38449929077288447,-0.6625285072121776,0.9217383587835264,-1.1044492003404638,0.26103110464403734,0.619171741197861,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,1.3162849902600815,-0.29451413807445087,1.5892312826899408	3367
Serine hydrolase activity	8	19	2.2133664169176317	0.026872394023572	Q9H3G5,P42785,P10619,O75976,Q9HB40,Q4J6C6,O14773,Q2T9J0	Functions	GO Molecular function	msigdb_gomf	1,2,106,175,16,268,20,157	20,175,106,2659,2326,1062,2,3261,806,869,285,371,157,268,542,2106,3194,1,16	3.9953969719732,1.3855706609057188,1.9473741733456051,-0.6153160198205229,-0.38449929077288447,0.26103110464403734,6.292167445838333,-1.4697807385854578,0.42266415546022,0.38263514328382814,0.995247055805408,0.8099100211162025,1.522027904662708,1.031696165695717,0.619171741197861,-0.25000179333226685,-1.2587149217723634,6.653184264123767,4.320727255133443	3367
Protein maturation	17	68	2.2069572603778864	0.0273170454109894	Q8TCT9,Q10713,P67812,Q96F07,Q10471,Q9NQH7,P42892,O75976,Q99538,O75844,Q92896,Q92542,Q9BU23,O75503,Q2T9J0,Q15392,Q9UG56	Processes and pathways	GO Biological process	msigdb_gobp	354,287,285,199,312,61,12,175,177,113,52,218,220,24,157,28,361	907,2308,2309,1813,24,113,175,3168,364,1553,2708,3170,3039,2159,1383,2161,1730,3280,2774,737,3048,1137,2780,12,1906,2597,2542,940,285,312,287,1070,1756,1579,1666,2736,28,157,542,2479,1081,3020,2280,1083,1346,354,218,52,199,2983,1527,1437,177,2804,220,670,2366,1869,2806,61,1793,676,361,1964,1115,3240,3270,1289	0.342355682402477,-0.38449929077288447,-0.38449929077288447,-0.11832544439901459,3.8514472696790003,1.8515558846925475,1.3855706609057188,-1.206907661975204,0.8099100211162025,0.010659648604851009,-0.6625285072121776,-1.206907661975204,-1.0035370570387363,-0.29451413807445087,0.09521457913715693,-0.29451413807445087,-0.07503752950409251,-1.5776059098511652,-0.7101048204413503,0.46244619964697814,-1.0035370570387363,0.2199786322467286,-0.7101048204413503,4.697545811150349,-0.1619123131620609,-0.5684611504154431,-0.5219578544209845,0.342355682402477,0.995247055805408,0.9217383587835264,0.995247055805408,0.26103110464403734,-0.07503752950409251,0.010659648604851009,-0.032043988936474706,-0.6625285072121776,3.7046073923024947,1.522027904662708,0.619171741197861,-0.4758002447614249,0.26103110464403734,-0.9536627270282968,-0.33934491131952355,0.26103110464403734,0.13707430384263497,0.8473984012280706,1.2109881782657737,2.810844890271643,1.2813706494606423,-0.9041772408267448,0.05307774962454346,0.09521457913715693,1.3855706609057188,-0.7101048204413503,1.2109881782657737,0.5412829355853829,-0.38449929077288447,-0.11832544439901459,-0.7101048204413503,2.6979179668449453,-0.07503752950409251,0.5412829355853829,0.8473984012280706,-0.1619123131620609,0.26103110464403734,-1.3634818904670298,-1.4697807385854578,0.1786609951774037	3367
Cis golgi network	8	14	2.20236017064568	0.0276398769822912	Q86VS8,Q14789,Q16706,O00461,P24390,Q99996,Q9NPR9,Q08379	Localization	GO Cellular component	msigdb_gocc	161,456,335,80,47,116,154,212	80,3083,47,2328,1010,212,456,335,161,1685,1686,116,154,516	2.377641277448686,-1.053799466605388,2.8943684331092254,-0.38449929077288447,0.30182221516229196,1.2109881782657737,0.6961379107980552,0.884673610049861,1.4881728202808266,-0.032043988936474706,-0.032043988936474706,1.8515558846925475,1.5557134250916398,0.657768615715268	3367
Nuclear pore complex assembly	8	9	2.190654659327296	0.0284767925020006	P49790,P57740,Q9BTX1,Q92621,Q9NQC3,P52948,P12270,Q8WYP5	Processes and pathways	GO Biological process	msigdb_gobp	739,646,165,338,221,806,392,465	392,739,806,646,882,465,338,165,221	0.7722057037721174,0.46244619964697814,0.42266415546022,0.5412829355853829,0.38263514328382814,0.6961379107980552,0.884673610049861,1.4541462370669627,1.2109881782657737	3367
membrane trafficking regulatory protein	8	21	2.1805091222587487	0.0292197433837613	Q15075,Q14108,Q8WTV0,P24390,Q8WU76,P11279,O00560,P13473	Functions	Panther Protein class	panther_protein_class	370,32,5,47,356,150,188,30	1052,385,188,2311,1723,150,30,47,32,370,2737,876,5,356,1685,1349,1269,3073,2632,1708,2575	0.26103110464403734,0.7722057037721174,1.3162849902600815,-0.38449929077288447,-0.07503752950409251,1.5557134250916398,3.6549956055948876,2.8943684331092254,3.5799366048175845,0.8099100211162025,-0.6625285072121776,0.38263514328382814,5.895453047698817,0.8473984012280706,-0.032043988936474706,0.13707430384263497,0.1786609951774037,-1.0035370570387363,-0.5684611504154431,-0.032043988936474706,-0.5219578544209845	3367
Intracellular calcium-sensing protein	6	13	2.17901476403197	0.0293305714498097	Q14257,P31949,P80303,Q9BRK5,O43852,Q02818	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	128,101,10,146,237,93	237,101,2337,10,93,128,2793,351,1940,2487,2424,668,146	1.103996441331084,2.0105143282367153,-0.38449929077288447,4.783524978682848,2.1658669221988482,1.7216629695769743,-0.7101048204413503,0.8473984012280706,-0.1619123131620609,-0.4758002447614249,-0.42998258634220327,0.5412829355853829,1.5892312826899408	3367
Calmodulin	6	13	2.17901476403197	0.0293305714498097	Q14257,P31949,P80303,Q9BRK5,O43852,Q02818	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	128,101,10,146,237,93	237,101,2337,10,93,128,2793,351,1940,2487,2424,668,146	1.103996441331084,2.0105143282367153,-0.38449929077288447,4.783524978682848,2.1658669221988482,1.7216629695769743,-0.7101048204413503,0.8473984012280706,-0.1619123131620609,-0.4758002447614249,-0.42998258634220327,0.5412829355853829,1.5892312826899408	3367
Actin filament based transport	9	10	2.1600651512486	0.0307676263227076	Q8WXH0,Q9Y4I1,O00159,Q9UH99,Q9UM54,O43707,O43795,O94832,O00401	Processes and pathways	GO Biological process	msigdb_gobp	404,784,522,280,778,627,386,365,476	522,476,627,386,365,873,404,280,778,784	0.619171741197861,0.657768615715268,0.5412829355853829,0.7722057037721174,0.8099100211162025,0.38263514328382814,0.7722057037721174,1.031696165695717,0.46244619964697814,0.46244619964697814	3367
Abnormal tissue metabolite concentration	6	15	2.157639984750713	0.0309558333938979	P07602,P06280,P17900,O43933,P06865,P07686	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,67,107,15,84,119	2814,15,2448,67,84,34,119,633,107,1996,394,654,3020,222,854	-0.7580513366787757,4.320727255133443,-0.4758002447614249,2.554155818031785,2.3177928418789855,3.297852942116772,1.8193146884450921,0.5412829355853829,1.9155840365977252,-0.2058028271615026,0.7722057037721174,0.5412829355853829,-0.9536627270282968,1.2109881782657737,0.42266415546022	3367
Transporter activity	43	144	2.157134628530985	0.0309951761652649	Q8WTV0,Q6NT16,Q8IXU6,P08183,L0R6Q1,Q70HW3,Q9UBX3,Q9H4L5,Q9BSK2,Q8TB61,Q9NS69,Q99808,O43772,Q14849,Q15043,O15118,Q99595,Q9H0U3,Q9Y487,Q9HD20,Q9C0H2,O43676,Q93050,Q9BZF1,O96008,P21796,P28288,P30825,O75964,P16615,P04062,Q9HC21,O60830,P61916,P41440,P13073,Q13423,P17900,Q9UI12,P45880,P60059,Q9H2D1,Q9P0J0	Functions	GO Molecular function	msigdb_gomf	5,7,8,132,251,13,142,147,274,270,26,158,42,49,315,46,178,322,186,185,56,58,62,192,308,309,197,201,89,211,210,360,96,99,102,232,233,107,249,115,241,123,261	251,2232,2305,440,1889,623,2510,46,1808,1295,58,2814,42,1639,96,2447,1980,1300,2582,630,2865,89,1719,1722,1895,690,1724,1304,2866,308,693,210,1215,1001,1896,2159,2710,132,2384,529,3338,1385,1556,1310,419,232,211,107,2529,864,2249,1732,2871,309,924,1562,1989,197,2533,1061,201,1394,2719,2875,1994,2591,102,115,449,3332,2922,1010,2398,641,2177,1140,806,1141,807,2781,645,2401,241,1011,871,99,2089,1069,1495,233,1150,3276,49,315,1584,3291,2275,594,7,2019,1250,460,13,8,1167,353,1683,270,5,972,62,889,839,765,178,158,2804,274,432,2133,192,56,322,2215,123,147,2218,1872,360,185,2631,26,261,142,512,1454,249,1285,1627,3296,1372,186,1376,2147	1.0679451413858796,-0.33934491131952355,-0.38449929077288447,0.6961379107980552,-0.1619123131620609,0.5412829355853829,-0.5219578544209845,2.8943684331092254,-0.11832544439901459,0.13707430384263497,2.754607952931739,-0.7580513366787757,3.0585160335120065,-0.032043988936474706,2.0730777150539357,-0.4758002447614249,-0.2058028271615026,0.13707430384263497,-0.5684611504154431,0.5412829355853829,-0.8063746087452964,2.227038925427992,-0.07503752950409251,-0.07503752950409251,-0.1619123131620609,0.5019846818620551,-0.07503752950409251,0.13707430384263497,-0.8063746087452964,0.9217383587835264,0.5019846818620551,1.2109881782657737,0.1786609951774037,0.30182221516229196,-0.1619123131620609,-0.29451413807445087,-0.6625285072121776,1.6557714498436458,-0.42998258634220327,0.619171741197861,-2.197689911987167,0.09521457913715693,0.010659648604851009,0.13707430384263497,0.7342826270023676,1.1398524773123389,1.2109881782657737,1.9155840365977252,-0.5219578544209845,0.38263514328382814,-0.33934491131952355,-0.07503752950409251,-0.8063746087452964,0.9217383587835264,0.342355682402477,0.010659648604851009,-0.2058028271615026,1.2813706494606423,-0.5219578544209845,0.26103110464403734,1.246272443990728,0.09521457913715693,-0.6625285072121776,-0.8063746087452964,-0.2058028271615026,-0.5684611504154431,2.0105143282367153,1.8515558846925475,0.6961379107980552,-2.024062737158297,-0.8550813717441338,0.30182221516229196,-0.42998258634220327,0.5412829355853829,-0.29451413807445087,0.2199786322467286,0.42266415546022,0.2199786322467286,0.42266415546022,-0.7101048204413503,0.5412829355853829,-0.42998258634220327,1.103996441331084,0.30182221516229196,0.38263514328382814,2.041867375489916,-0.25000179333226685,0.26103110464403734,0.05307774962454346,1.1398524773123389,0.2199786322467286,-1.523502876429464,2.8943684331092254,0.9217383587835264,0.010659648604851009,-1.632089162713181,-0.33934491131952355,0.580344223839915,4.910685979818012,-0.2058028271615026,0.1786609951774037,0.6961379107980552,4.433541950109594,4.889640280593516,0.2199786322467286,0.8473984012280706,-0.032043988936474706,1.031696165695717,5.895453047698817,0.342355682402477,2.669400494336479,0.38263514328382814,0.42266415546022,0.46244619964697814,1.3855706609057188,1.522027904662708,-0.7101048204413503,1.031696165695717,0.7342826270023676,-0.25000179333226685,1.3162849902600815,2.782782542710472,0.9217383587835264,-0.29451413807445087,1.7869199137107399,1.5892312826899408,-0.29451413807445087,-0.11832544439901459,0.8473984012280706,1.3510176219205223,-0.5684611504154431,3.802828202328214,1.0679451413858796,1.6225833456176855,0.657768615715268,0.09521457913715693,1.103996441331084,0.1786609951774037,0.010659648604851009,-1.632089162713181,0.13707430384263497,1.3510176219205223,0.13707430384263497,-0.25000179333226685	3367
EF-hand domain pair [IPR011992]	13	47	2.153393750662108	0.0312877463239016	Q14257,Q13813,Q9Y680,P31949,O75071,P80303,Q66K14,Q9BRK5,P07384,O43852,Q9UBC2,Q02818,Q03001	Sequence	InterPro Superfamily	interpro_homologous_superfamily	128,214,100,101,39,10,169,146,240,237,292,93,191	627,237,39,3325,630,690,2158,240,1002,1987,1648,1730,1390,2073,3248,101,1902,1063,332,2337,10,93,191,214,128,2735,2793,169,2019,1940,1856,880,2487,2424,883,1169,832,3217,668,146,1361,1791,292,3344,1285,565,100	0.5412829355853829,1.103996441331084,3.16587922270476,-1.9101855426565795,0.5412829355853829,0.5019846818620551,-0.29451413807445087,1.103996441331084,0.30182221516229196,-0.2058028271615026,-0.032043988936474706,-0.07503752950409251,0.09521457913715693,-0.25000179333226685,-1.416440179685344,2.0105143282367153,-0.1619123131620609,0.26103110464403734,0.884673610049861,-0.38449929077288447,4.783524978682848,2.1658669221988482,1.3162849902600815,1.2109881782657737,1.7216629695769743,-0.6625285072121776,-0.7101048204413503,1.419946185566603,-0.2058028271615026,-0.1619123131620609,-0.11832544439901459,0.38263514328382814,-0.4758002447614249,-0.42998258634220327,0.38263514328382814,0.2199786322467286,0.42266415546022,-1.3109065691871442,0.5412829355853829,1.5892312826899408,0.13707430384263497,-0.07503752950409251,0.995247055805408,-2.197689911987167,0.1786609951774037,0.619171741197861,2.041867375489916	3367
Abnormal retinal vascular morphology	16	51	2.1454923049928616	0.031913506015031	Q6P2Q9,P07602,P16278,Q9Y4P3,P04439,P10619,Q9UIG0,P35222,P17900,Q9NZJ7,P07686,P06865,Q8WYQ5,O60333,Q13510,Q96DF8	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	546,34,68,302,527,106,514,531,107,222,119,84,319,479,90,290	681,1207,1638,1979,1640,479,1300,792,2650,1721,527,84,34,119,2318,106,2768,2769,68,107,1479,2164,1391,576,531,2254,3289,2590,1994,2255,936,2880,2081,1405,1495,2406,1240,90,3284,1847,546,885,319,1090,969,2359,290,2627,222,514,302	0.5019846818620551,0.1786609951774037,-0.032043988936474706,-0.2058028271615026,-0.032043988936474706,0.657768615715268,0.13707430384263497,0.42266415546022,-0.6153160198205229,-0.07503752950409251,0.619171741197861,2.3177928418789855,3.297852942116772,1.8193146884450921,-0.38449929077288447,1.9473741733456051,-0.7101048204413503,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.05307774962454346,-0.29451413807445087,0.09521457913715693,0.580344223839915,0.619171741197861,-0.33934491131952355,-1.632089162713181,-0.5684611504154431,-0.2058028271615026,-0.33934491131952355,0.342355682402477,-0.8063746087452964,-0.25000179333226685,0.09521457913715693,0.05307774962454346,-0.42998258634220327,0.1786609951774037,2.227038925427992,-1.5776059098511652,-0.11832544439901459,0.619171741197861,0.38263514328382814,0.9217383587835264,0.26103110464403734,0.342355682402477,-0.38449929077288447,0.995247055805408,-0.5684611504154431,1.2109881782657737,0.657768615715268,0.9585953053509725	3367
Phospholipid metabolism	12	52	2.1406510543508337	0.0323021883565624	Q92604,Q8NCC3,Q10713,Q9BZF1,P42356,Q96N66,P35790,O95674,Q8IV08,Q8IY17,Q9NQZ5,Q9UG56	Processes and pathways	Reactome Pathways	msigdb_reactome	259,0,287,192,198,133,48,330,151,316,323,361	570,1975,624,2702,2313,330,2956,2325,2662,2388,48,932,198,1063,738,2922,2400,2001,1404,1571,287,2010,1073,1663,1335,1774,151,316,713,2023,403,1345,0,883,2202,3069,259,133,1176,3321,975,2804,2032,1099,192,1868,3198,2696,323,1706,361,566	0.580344223839915,-0.2058028271615026,0.5412829355853829,-0.6625285072121776,-0.38449929077288447,0.884673610049861,-0.9041772408267448,-0.38449929077288447,-0.6153160198205229,-0.42998258634220327,2.8943684331092254,0.342355682402477,1.2813706494606423,0.26103110464403734,0.46244619964697814,-0.8550813717441338,-0.42998258634220327,-0.2058028271615026,0.09521457913715693,0.010659648604851009,0.995247055805408,-0.2058028271615026,0.26103110464403734,-0.032043988936474706,0.13707430384263497,-0.07503752950409251,1.5557134250916398,0.9217383587835264,0.5019846818620551,-0.2058028271615026,0.7722057037721174,0.13707430384263497,6.753408671655479,0.38263514328382814,-0.29451413807445087,-1.0035370570387363,1.0679451413858796,1.6557714498436458,0.2199786322467286,-1.853811091154964,0.342355682402477,-0.7101048204413503,-0.2058028271615026,0.26103110464403734,1.3162849902600815,-0.11832544439901459,-1.2587149217723634,-0.6153160198205229,0.9217383587835264,-0.032043988936474706,0.8473984012280706,0.619171741197861	3367
Abnormal retinal artery morphology	8	20	2.131523440898892	0.0330460434089341	P07602,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,68,106,107,222,119,84,90	1638,1979,84,34,119,106,2769,68,107,1391,2254,2081,1405,90,3284,969,2359,222,514,302	-0.032043988936474706,-0.2058028271615026,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.09521457913715693,-0.33934491131952355,-0.25000179333226685,0.09521457913715693,2.227038925427992,-1.5776059098511652,0.342355682402477,-0.38449929077288447,1.2109881782657737,0.657768615715268,0.9585953053509725	3367
Protease	23	87	2.130578090237847	0.0331239161543264	Q9H3G5,P42785,P42892,Q9NZ08,Q9HB40,O14773,Q4J6C6,Q2T9J0,P81605,P55786,Q01804,P67812,Q70CQ2,O75976,Q99538,Q9NQH7,Q9H4L4,Q8TCT9,Q9UIQ6,P10619,O75844,P07384,Q16740	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	1,2,12,148,16,20,268,157,286,162,163,285,298,175,177,61,359,354,103,106,113,240,371	2813,3166,20,1469,1813,113,175,1128,390,240,3005,106,2657,2068,1730,485,2455,2456,2326,1062,1137,2780,2,12,2877,3261,2597,2882,580,806,869,3282,162,2542,285,286,451,163,1241,2613,2736,371,157,268,542,2479,3292,1249,298,2889,3194,1025,1169,354,1601,2120,971,1032,3316,1782,1352,2124,2849,1437,2209,3304,177,1699,1,1954,359,1791,16,61,3106,509,2573,148,2372,1188,103,619,1117,731,2052,1289,2645	-0.7580513366787757,-1.206907661975204,3.9953969719732,0.05307774962454346,-0.11832544439901459,1.8515558846925475,1.3855706609057188,0.2199786322467286,0.7722057037721174,1.103996441331084,-0.9536627270282968,1.9473741733456051,-0.6153160198205229,-0.25000179333226685,-0.07503752950409251,0.657768615715268,-0.4758002447614249,-0.4758002447614249,-0.38449929077288447,0.26103110464403734,0.2199786322467286,-0.7101048204413503,6.292167445838333,4.697545811150349,-0.8063746087452964,-1.4697807385854578,-0.5684611504154431,-0.8063746087452964,0.580344223839915,0.42266415546022,0.38263514328382814,-1.5776059098511652,1.4541462370669627,-0.5219578544209845,0.995247055805408,0.995247055805408,0.6961379107980552,1.4541462370669627,0.1786609951774037,-0.5684611504154431,-0.6625285072121776,0.8099100211162025,1.522027904662708,1.031696165695717,0.619171741197861,-0.4758002447614249,-1.632089162713181,0.1786609951774037,0.9585953053509725,-0.8063746087452964,-1.2587149217723634,0.30182221516229196,0.2199786322467286,0.8473984012280706,0.010659648604851009,-0.25000179333226685,0.342355682402477,0.30182221516229196,-1.7978135821100152,-0.07503752950409251,0.13707430384263497,-0.25000179333226685,-0.7580513366787757,0.09521457913715693,-0.29451413807445087,-1.7421936575233459,1.3855706609057188,-0.032043988936474706,6.653184264123767,-0.1619123131620609,0.8473984012280706,-0.07503752950409251,4.320727255133443,2.6979179668449453,-1.053799466605388,0.657768615715268,-0.5219578544209845,1.5892312826899408,-0.38449929077288447,0.2199786322467286,2.0105143282367153,0.580344223839915,0.26103110464403734,0.5019846818620551,-0.2058028271615026,0.1786609951774037,-0.5684611504154431	3367
Cell surface	20	74	2.120901271450565	0.0339301116549111	Q8WTV0,P08183,P42892,Q12846,P11279,Q00839,P11717,O15031,P01889,P09104,P05067,P55899,Q13641,Q8TCT9,P19022,Q9NWH9,P41440,Q08431,P02786,O75955	Localization	GO Cellular component	msigdb_gocc	5,132,12,144,150,395,156,524,294,196,83,86,454,354,346,511,102,243,239,238	524,1378,1469,1000,1645,238,1130,2709,294,239,2316,527,83,2064,1896,3039,921,2159,132,2384,2711,196,2958,2525,1307,2161,1557,150,156,1986,1647,2068,1730,3120,346,1989,1393,2774,2823,1652,2328,3046,102,12,2535,1740,3282,1997,86,395,1659,243,144,2971,1325,1071,1577,2271,454,3018,747,706,2102,1341,354,5,2203,2750,2034,1364,511,2376,1970,1376	0.619171741197861,0.09521457913715693,0.05307774962454346,0.30182221516229196,-0.032043988936474706,1.103996441331084,0.2199786322467286,-0.6625285072121776,0.9585953053509725,1.103996441331084,-0.38449929077288447,0.619171741197861,2.3477816274627044,-0.25000179333226685,-0.1619123131620609,-1.0035370570387363,0.342355682402477,-0.29451413807445087,1.6557714498436458,-0.42998258634220327,-0.6625285072121776,1.2813706494606423,-0.9041772408267448,-0.5219578544209845,0.13707430384263497,-0.29451413807445087,0.010659648604851009,1.5557134250916398,1.522027904662708,-0.2058028271615026,-0.032043988936474706,-0.25000179333226685,-0.07503752950409251,-1.1044492003404638,0.8473984012280706,-0.2058028271615026,0.09521457913715693,-0.7101048204413503,-0.7580513366787757,-0.032043988936474706,-0.38449929077288447,-1.0035370570387363,2.0105143282367153,4.697545811150349,-0.5219578544209845,-0.07503752950409251,-1.5776059098511652,-0.2058028271615026,2.3177928418789855,0.7722057037721174,-0.032043988936474706,1.103996441331084,1.5892312826899408,-0.9041772408267448,0.13707430384263497,0.26103110464403734,0.010659648604851009,-0.33934491131952355,0.6961379107980552,-0.9536627270282968,0.46244619964697814,0.5019846818620551,-0.25000179333226685,0.13707430384263497,0.8473984012280706,5.895453047698817,-0.29451413807445087,-0.6625285072121776,-0.2058028271615026,0.13707430384263497,0.657768615715268,-0.38449929077288447,-0.1619123131620609,0.13707430384263497	3367
Progressive neurologic deterioration	7	21	2.1155374098416115	0.0343841699912434	P54802,P07602,P16278,Q9NZJ7,Q9NPL8,P07686,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	65,34,68,222,87,119,210	2814,210,34,119,2524,633,68,1218,2164,576,802,65,1568,1745,287,2551,1509,1772,2210,87,222	-0.7580513366787757,1.2109881782657737,3.297852942116772,1.8193146884450921,-0.5219578544209845,0.5412829355853829,2.554155818031785,0.1786609951774037,-0.29451413807445087,0.580344223839915,0.42266415546022,2.640766626646635,0.010659648604851009,-0.07503752950409251,0.995247055805408,-0.5219578544209845,0.05307774962454346,-0.07503752950409251,-0.29451413807445087,2.3177928418789855,1.2109881782657737	3367
Supranuclear gaze palsy	12	20	2.115309519531636	0.0344035756527552	P07602,Q99720,Q9UEY8,P61916,Q9UDR5,Q96RL7,O15118,Q969N2,P35637,Q9NZJ7,Q96RR1,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,36,437,99,774,339,46,718,421,222,721,210	2233,1202,46,210,34,1476,736,421,1745,99,1923,945,1330,718,339,721,36,222,774,437	-0.33934491131952355,0.1786609951774037,2.8943684331092254,1.2109881782657737,3.297852942116772,0.05307774962454346,0.46244619964697814,0.7342826270023676,-0.07503752950409251,2.041867375489916,-0.1619123131620609,0.342355682402477,0.13707430384263497,0.5019846818620551,0.884673610049861,0.5019846818620551,3.218961116049131,1.2109881782657737,0.46244619964697814,0.7342826270023676	3367
Abnormal circulating cholesterol concentration	17	33	2.112866158899682	0.0346122250865237	P07602,P61916,Q8WXH0,Q10471,Q15800,Q14739,P50402,Q7Z5J4,Q9NZJ7,O75431,P42858,P34913,Q8N511,Q15392,P37268,Q15904,Q9UBM7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,99,404,312,105,76,578,597,222,443,265,88,257,28,367,126,63	443,1816,2452,34,88,367,2876,265,3049,578,2832,646,99,1571,312,1072,2093,76,589,28,2098,105,126,597,2845,257,2846,404,1441,1537,222,63,1285	0.6961379107980552,-0.11832544439901459,-0.4758002447614249,3.297852942116772,2.2574227850195774,0.8099100211162025,-0.8063746087452964,1.031696165695717,-1.0035370570387363,0.580344223839915,-0.7580513366787757,0.5412829355853829,2.041867375489916,0.010659648604851009,0.9217383587835264,0.26103110464403734,-0.25000179333226685,2.4369781355796594,0.580344223839915,3.7046073923024947,-0.25000179333226685,1.9790170949571289,1.7543699026919297,0.580344223839915,-0.7580513366787757,1.0679451413858796,-0.7580513366787757,0.7722057037721174,0.09521457913715693,0.05307774962454346,1.2109881782657737,2.669400494336479,0.1786609951774037	3367
Vacuolar transport	8	50	2.112649274320152	0.034630797946797	Q86VS8,Q14108,P07602,P20645,O15118,P13473,P11279,P11717	Processes and pathways	GO Biological process	msigdb_gobp	161,32,34,44,46,30,150,156	1713,1465,787,2511,46,1891,2817,1553,34,2712,150,156,30,44,1009,1907,1745,1011,1324,32,954,3133,547,161,1086,2690,2118,1349,2360,3348,1608,339,975,1696,2984,430,3073,2040,1043,2219,897,2044,222,2575,616,902,2049,3322,1710,412	-0.07503752950409251,0.05307774962454346,0.42266415546022,-0.5219578544209845,2.8943684331092254,-0.1619123131620609,-0.7580513366787757,0.010659648604851009,3.297852942116772,-0.6625285072121776,1.5557134250916398,1.522027904662708,3.6549956055948876,2.976917059317765,0.30182221516229196,-0.1619123131620609,-0.07503752950409251,0.30182221516229196,0.13707430384263497,3.5799366048175845,0.342355682402477,-1.1044492003404638,0.619171741197861,1.4881728202808266,0.26103110464403734,-0.6153160198205229,-0.25000179333226685,0.13707430384263497,-0.38449929077288447,-2.3153084893943583,0.010659648604851009,0.884673610049861,0.342355682402477,-0.032043988936474706,-0.9041772408267448,0.7342826270023676,-1.0035370570387363,-0.2058028271615026,0.30182221516229196,-0.29451413807445087,0.38263514328382814,-0.2058028271615026,1.2109881782657737,-0.5219578544209845,0.580344223839915,0.38263514328382814,-0.2058028271615026,-1.853811091154964,-0.032043988936474706,0.7722057037721174	3367
Loss of speech	6	20	2.103141938379556	0.0354533638915743	P07602,P61916,P17900,Q9NZJ7,O15118,P50897	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,99,107,222,46,29	208,46,2814,3229,2315,34,633,107,29,1829,1568,1745,644,99,945,1153,877,1790,222,1460	1.2109881782657737,2.8943684331092254,-0.7580513366787757,-1.3634818904670298,-0.38449929077288447,3.297852942116772,0.5412829355853829,1.9155840365977252,3.679843814797915,-0.11832544439901459,0.010659648604851009,-0.07503752950409251,0.5412829355853829,2.041867375489916,0.342355682402477,0.2199786322467286,0.38263514328382814,-0.07503752950409251,1.2109881782657737,0.09521457913715693	3367
Arthritis	10	45	2.091819754283572	0.0364546425581158	Q14108,P06280,Q14739,P01889,Q9NZ08,O75844,Q8WVQ1,Q13510,P04062,P60891	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,67,76,294,148,113,318,90,210,31	907,3034,3229,113,2519,294,1816,210,67,2385,1307,2819,1647,1391,2821,1650,1740,1228,2079,641,1400,2081,644,31,871,1571,2406,1410,90,32,76,1243,711,828,318,969,2359,1605,339,674,509,148,676,3080,1460	0.342355682402477,-1.0035370570387363,-1.3634818904670298,1.8515558846925475,-0.5219578544209845,0.9585953053509725,-0.11832544439901459,1.2109881782657737,2.554155818031785,-0.42998258634220327,0.13707430384263497,-0.7580513366787757,-0.032043988936474706,0.09521457913715693,-0.7580513366787757,-0.032043988936474706,-0.07503752950409251,0.1786609951774037,-0.25000179333226685,0.5412829355853829,0.09521457913715693,-0.25000179333226685,0.5412829355853829,3.6549956055948876,0.38263514328382814,0.010659648604851009,-0.42998258634220327,0.09521457913715693,2.227038925427992,3.5799366048175845,2.4369781355796594,0.1786609951774037,0.5019846818620551,0.42266415546022,0.9217383587835264,0.342355682402477,-0.38449929077288447,0.010659648604851009,0.884673610049861,0.5412829355853829,0.657768615715268,1.5892312826899408,0.5412829355853829,-1.0035370570387363,0.09521457913715693	3367
External side of plasma membrane	7	22	2.0885820406726854	0.036745363227447	P41440,P08183,P42892,P55899,Q08431,P02786,P11279	Localization	GO Cellular component	msigdb_gocc	102,132,12,86,243,239,150	238,1130,2709,239,2316,2064,921,132,150,2068,1730,2774,102,12,2535,1740,86,243,747,2102,1341,2376	1.103996441331084,0.2199786322467286,-0.6625285072121776,1.103996441331084,-0.38449929077288447,-0.25000179333226685,0.342355682402477,1.6557714498436458,1.5557134250916398,-0.25000179333226685,-0.07503752950409251,-0.7101048204413503,2.0105143282367153,4.697545811150349,-0.5219578544209845,-0.07503752950409251,2.3177928418789855,1.103996441331084,0.46244619964697814,-0.25000179333226685,0.13707430384263497,-0.38449929077288447	3367
Organophosphate ester transport	11	25	2.082808568114676	0.0372686762806835	Q14108,Q9BZF1,Q9H2D1,P61916,Q8WTV0,P41440,P08183,Q9BSK2,Q8TB61,Q9HC21,Q99808	Processes and pathways	GO Biological process	msigdb_gobp	32,192,123,99,5,102,132,274,270,360,158	1639,1001,132,1310,419,924,3121,102,2922,99,2089,1410,32,2019,270,5,889,158,274,192,2215,123,360,1708,3296	-0.032043988936474706,0.30182221516229196,1.6557714498436458,0.13707430384263497,0.7342826270023676,0.342355682402477,-1.1044492003404638,2.0105143282367153,-0.8550813717441338,2.041867375489916,-0.25000179333226685,0.09521457913715693,3.5799366048175845,-0.2058028271615026,1.031696165695717,5.895453047698817,0.38263514328382814,1.522027904662708,1.031696165695717,1.3162849902600815,-0.29451413807445087,1.7869199137107399,0.8473984012280706,-0.032043988936474706,-1.632089162713181	3367
metalloprotease	8	24	2.0753862292742724	0.037950753428763	Q10713,P55786,Q9UIQ6,P42892,Q9NZ08,O75844,P02786,Q9NQH7	Functions	Panther Protein class	panther_protein_class	287,162,103,12,148,113,239,61	1469,1813,113,390,239,2657,2068,1820,2456,1394,12,580,162,287,542,2117,2124,1437,1699,61,2573,148,103,1289	0.05307774962454346,-0.11832544439901459,1.8515558846925475,0.7722057037721174,1.103996441331084,-0.6153160198205229,-0.25000179333226685,-0.11832544439901459,-0.4758002447614249,0.09521457913715693,4.697545811150349,0.580344223839915,1.4541462370669627,0.995247055805408,0.619171741197861,-0.25000179333226685,-0.25000179333226685,0.09521457913715693,-0.032043988936474706,2.6979179668449453,-0.5219578544209845,1.5892312826899408,2.0105143282367153,0.1786609951774037	3367
Arteriosclerosis	6	17	2.073195072736448	0.038154128769003	P61916,P16278,O75844,O15118,P34913,Q13510	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	99,68,113,46,88,90	46,1644,113,1816,68,797,483,3151,88,1994,2876,99,1240,90,215,970,615	2.8943684331092254,-0.032043988936474706,1.8515558846925475,-0.11832544439901459,2.554155818031785,0.42266415546022,0.657768615715268,-1.1554855115344582,2.2574227850195774,-0.2058028271615026,-0.8063746087452964,2.041867375489916,0.1786609951774037,2.227038925427992,1.2109881782657737,0.342355682402477,0.580344223839915	3367
Alcohol binding	7	17	2.072908238967245	0.038180820129104	Q9BZF1,Q14108,P61916,Q14849,Q9H4L5,O15118,P45880	Functions	GO Molecular function	msigdb_gomf	192,32,99,49,147,46,115	1975,46,1812,2315,2710,309,3121,575,1061,532,115,99,32,49,192,2215,147	-0.2058028271615026,2.8943684331092254,-0.11832544439901459,-0.38449929077288447,-0.6625285072121776,0.9217383587835264,-1.1044492003404638,0.580344223839915,0.26103110464403734,0.619171741197861,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,1.3162849902600815,-0.29451413807445087,1.5892312826899408	3367
Steroid binding	8	22	2.064700657082469	0.0389513323824173	Q14108,Q9BZF1,P61916,Q14849,Q9H4L5,O15118,P45880,P04062	Functions	GO Molecular function	msigdb_gomf	32,192,99,49,147,46,115,210	1201,46,1808,2315,210,1215,2710,309,924,3121,1061,532,1994,115,99,32,49,839,2133,192,2215,147	0.1786609951774037,2.8943684331092254,-0.11832544439901459,-0.38449929077288447,1.2109881782657737,0.1786609951774037,-0.6625285072121776,0.9217383587835264,0.342355682402477,-1.1044492003404638,0.26103110464403734,0.619171741197861,-0.2058028271615026,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,0.42266415546022,-0.25000179333226685,1.3162849902600815,-0.29451413807445087,1.5892312826899408	3367
Biliary tract abnormality	8	29	2.0611927243015336	0.039284657380425	Q14108,P07602,P09601,Q14739,O43933,Q9NZJ7,O96028,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,34,40,76,15,222,92,210	2814,15,690,92,1816,210,34,40,1647,633,3149,1062,2075,1996,287,453,1924,32,76,1509,970,971,1694,2627,2501,222,2946,854,1804	-0.7580513366787757,4.320727255133443,0.5019846818620551,2.1658669221988482,-0.11832544439901459,1.2109881782657737,3.297852942116772,3.1123997852653797,-0.032043988936474706,0.5412829355853829,-1.1554855115344582,0.26103110464403734,-0.25000179333226685,-0.2058028271615026,0.995247055805408,0.6961379107980552,-0.1619123131620609,3.5799366048175845,2.4369781355796594,0.05307774962454346,0.342355682402477,0.342355682402477,-0.032043988936474706,-0.5684611504154431,-0.4758002447614249,1.2109881782657737,-0.8550813717441338,0.42266415546022,-0.07503752950409251	3367
Incoordination	11	70	2.055832470732427	0.0397986670238117	Q6DKK2,P07602,Q9UJX6,Q9NR77,Q9NZJ7,O14773,P42858,O75503,Q13510,O00754,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	97,34,134,278,222,20,265,24,90,208,210	2233,208,20,1202,1293,2814,858,688,3325,24,912,2156,210,920,34,1386,1310,1818,633,2164,925,576,2168,2395,932,265,1484,2396,1995,1141,1745,2400,644,3157,1494,1919,2091,2408,287,945,90,2093,1761,1926,1245,2482,97,824,2484,1023,655,1424,970,1431,837,1608,721,1697,2210,1443,2627,2569,278,1185,222,2143,774,2144,134,905	-0.33934491131952355,1.2109881782657737,3.9953969719732,0.1786609951774037,0.13707430384263497,-0.7580513366787757,0.38263514328382814,0.5019846818620551,-1.9101855426565795,3.8514472696790003,0.342355682402477,-0.29451413807445087,1.2109881782657737,0.342355682402477,3.297852942116772,0.09521457913715693,0.13707430384263497,-0.11832544439901459,0.5412829355853829,-0.29451413807445087,0.342355682402477,0.580344223839915,-0.29451413807445087,-0.42998258634220327,0.342355682402477,1.031696165695717,0.05307774962454346,-0.42998258634220327,-0.2058028271615026,0.2199786322467286,-0.07503752950409251,-0.42998258634220327,0.5412829355853829,-1.1554855115344582,0.05307774962454346,-0.1619123131620609,-0.25000179333226685,-0.42998258634220327,0.995247055805408,0.342355682402477,2.227038925427992,-0.25000179333226685,-0.07503752950409251,-0.1619123131620609,0.1786609951774037,-0.4758002447614249,2.0730777150539357,0.42266415546022,-0.4758002447614249,0.30182221516229196,0.5412829355853829,0.09521457913715693,0.342355682402477,0.09521457913715693,0.42266415546022,0.010659648604851009,0.5019846818620551,-0.032043988936474706,-0.29451413807445087,0.09521457913715693,-0.5684611504154431,-0.5219578544209845,1.031696165695717,0.2199786322467286,1.2109881782657737,-0.25000179333226685,0.46244619964697814,-0.25000179333226685,1.6557714498436458,0.38263514328382814	3367
Abnormality of head blood vessel	8	22	2.053481707024245	0.0400258821018506	P07602,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,68,106,107,222,119,84,90	1202,1638,1979,84,34,119,106,2769,68,107,1391,2254,738,2081,1405,90,3284,969,2359,222,514,302	0.1786609951774037,-0.032043988936474706,-0.2058028271615026,2.3177928418789855,3.297852942116772,1.8193146884450921,1.9473741733456051,-0.7101048204413503,2.554155818031785,1.9155840365977252,0.09521457913715693,-0.33934491131952355,0.46244619964697814,-0.25000179333226685,0.09521457913715693,2.227038925427992,-1.5776059098511652,0.342355682402477,-0.38449929077288447,1.2109881782657737,0.657768615715268,0.9585953053509725	3367
Myosin head, motor domain [IPR001609]	8	10	2.0517959317019137	0.0401894988571815	Q9Y4I1,O00159,P35580,Q7Z406,Q9UM54,O43795,O94832,P35579	Sequence	InterPro Domain	interpro_domain	784,522,447,711,778,386,365,737	522,386,365,737,447,873,1842,711,778,784	0.619171741197861,0.7722057037721174,0.8099100211162025,0.46244619964697814,0.6961379107980552,0.38263514328382814,-0.11832544439901459,0.5019846818620551,0.46244619964697814,0.46244619964697814	3367
Sterol binding	7	17	2.051704254076848	0.0401984130773613	Q9BZF1,Q14108,P61916,Q14849,Q9H4L5,O15118,P45880	Functions	GO Molecular function	msigdb_gomf	192,32,99,49,147,46,115	46,2315,2710,309,924,3121,1061,532,115,99,32,49,839,2133,192,2215,147	2.8943684331092254,-0.38449929077288447,-0.6625285072121776,0.9217383587835264,0.342355682402477,-1.1044492003404638,0.26103110464403734,0.619171741197861,1.8515558846925475,2.041867375489916,3.5799366048175845,2.8943684331092254,0.42266415546022,-0.25000179333226685,1.3162849902600815,-0.29451413807445087,1.5892312826899408	3367
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	6	12	2.0490866183780425	0.0404536457635611	P09601,P51648,P05067,P60059,P46379,P50402	Processes and pathways	Reactome Pathways	msigdb_reactome	40,333,83,241,54,578	2814,2150,83,40,54,578,333,241,1747,585,2021,1708	-0.7580513366787757,-0.29451413807445087,2.3477816274627044,3.1123997852653797,2.782782542710472,0.580344223839915,0.884673610049861,1.103996441331084,-0.07503752950409251,0.580344223839915,-0.2058028271615026,-0.032043988936474706	3367
Deafness	20	53	2.045959901734988	0.0407603159732496	Q9NSV4,O43933,Q15031,O75648,Q9NR28,P60891,Q9Y276,Q7Z406,O95831,Q96RR1,Q9Y4A5,O95677,Q9UG56,O60313,P19447,Q9UM54,Q8N2K0,Q16740,O76024,P35579	Drugs and Diseases	Protein Atlas Disease involvement	protein_atlas_disease_involvement	675,15,397,389,291,31,854,711,417,721,729,692,361,209,483,778,659,371,364,737	2237,15,209,1296,2151,1472,389,364,692,417,2768,797,483,1732,1559,2872,865,3047,1134,737,1062,1319,2333,1139,1996,31,1912,1146,2786,1838,2181,1497,2791,2735,397,2551,1926,371,711,659,2199,1516,1777,1094,721,2215,291,1876,675,361,778,854,729	-0.33934491131952355,4.320727255133443,1.2109881782657737,0.13707430384263497,-0.29451413807445087,0.05307774962454346,0.7722057037721174,0.8099100211162025,0.5019846818620551,0.7342826270023676,-0.7101048204413503,0.42266415546022,0.657768615715268,-0.07503752950409251,0.010659648604851009,-0.8063746087452964,0.38263514328382814,-1.0035370570387363,0.2199786322467286,0.46244619964697814,0.26103110464403734,0.13707430384263497,-0.38449929077288447,0.2199786322467286,-0.2058028271615026,3.6549956055948876,-0.1619123131620609,0.2199786322467286,-0.7101048204413503,-0.11832544439901459,-0.29451413807445087,0.05307774962454346,-0.7101048204413503,-0.6625285072121776,0.7722057037721174,-0.5219578544209845,-0.1619123131620609,0.8099100211162025,0.5019846818620551,0.5412829355853829,-0.29451413807445087,0.05307774962454346,-0.07503752950409251,0.26103110464403734,0.5019846818620551,-0.29451413807445087,0.995247055805408,-0.11832544439901459,0.5412829355853829,0.8473984012280706,0.46244619964697814,0.42266415546022,0.5019846818620551	3367
Status epilepticus	9	53	2.043796663469733	0.0409736389302095	P07602,Q96F07,P42892,Q9H1C4,Q9NZJ7,Q9Y487,Q8IYB7,Q13510,Q15392	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,199,12,275,222,186,317,90,28	1635,1126,1720,2157,1215,34,2318,1556,1003,1990,736,2591,12,2175,3309,2723,2396,2830,1829,2080,2177,1066,696,3157,1404,1232,1494,812,2785,1752,2610,2788,90,1761,28,1077,317,199,973,2125,721,380,3294,275,1275,724,2504,2046,615,222,2143,902,186	-0.032043988936474706,0.2199786322467286,-0.07503752950409251,-0.29451413807445087,0.1786609951774037,3.297852942116772,-0.38449929077288447,0.010659648604851009,0.30182221516229196,-0.2058028271615026,0.46244619964697814,-0.5684611504154431,4.697545811150349,-0.29451413807445087,-1.7978135821100152,-0.6625285072121776,-0.42998258634220327,-0.7580513366787757,-0.11832544439901459,-0.25000179333226685,-0.29451413807445087,0.26103110464403734,0.5019846818620551,-1.1554855115344582,0.09521457913715693,0.1786609951774037,0.05307774962454346,0.42266415546022,-0.7101048204413503,-0.07503752950409251,-0.5684611504154431,-0.7101048204413503,2.227038925427992,-0.07503752950409251,3.7046073923024947,0.26103110464403734,0.9217383587835264,1.2813706494606423,0.342355682402477,-0.25000179333226685,0.5019846818620551,0.8099100211162025,-1.632089162713181,1.031696165695717,0.1786609951774037,0.5019846818620551,-0.4758002447614249,-0.2058028271615026,0.580344223839915,1.2109881782657737,-0.25000179333226685,0.38263514328382814,1.3510176219205223	3367
Cellular hormone metabolic process	7	17	2.0376271626073232	0.0415872334545541	O95470,Q8NBN7,P42892,Q14849,Q15648,Q9HB40,Q8NBQ5	Processes and pathways	GO Biological process	msigdb_gobp	160,229,12,49,398,16,464	2152,160,3085,1061,12,1996,1401,49,398,651,493,229,464,1424,2210,16,1546	-0.29451413807445087,1.4881728202808266,-1.053799466605388,0.26103110464403734,4.697545811150349,-0.2058028271615026,0.09521457913715693,2.8943684331092254,0.7722057037721174,0.5412829355853829,0.657768615715268,1.1755156156311373,0.6961379107980552,0.09521457913715693,-0.29451413807445087,4.320727255133443,0.05307774962454346	3367
Spectrin repeat [IPR002017]	7	10	2.035017774099164	0.041849084582235	Q13813,Q8WXH0,P46939,O43707,Q9UPN3,O75962,Q03001	Sequence	InterPro Repeat	interpro_repeat	214,404,332,627,565,573,191	1293,627,573,1002,332,744,191,214,404,565	0.13707430384263497,0.5412829355853829,0.580344223839915,0.30182221516229196,0.884673610049861,0.46244619964697814,1.3162849902600815,1.2109881782657737,0.7722057037721174,0.619171741197861	3367
Endocytic vesicle	14	82	2.0335905755712496	0.0419928928453534	Q14108,P02786,Q8WTV0,P20645,Q16625,Q9H1C4,O00461,Q12846,Q9Y487,P13473,Q5KU26,P11279,P11717,Q93050	Localization	GO Cellular component	msigdb_gocc	32,239,5,44,168,275,80,144,186,30,120,150,156,62	522,1052,476,80,787,1205,1295,733,3297,1471,2648,631,918,294,239,527,2868,794,1897,795,1307,1557,150,156,30,2322,2388,44,2774,1652,1314,448,2078,3155,2598,1907,2726,1142,2000,2676,2543,2001,1011,2968,2087,1232,1571,1324,144,873,1577,491,2184,32,369,2097,1929,2737,2477,168,2102,120,1508,2108,2559,2115,5,2491,62,761,975,2212,275,1361,777,2858,778,1710,186,988,1631,1888	0.619171741197861,0.26103110464403734,0.657768615715268,2.377641277448686,0.42266415546022,0.1786609951774037,0.13707430384263497,0.46244619964697814,-1.686951965968084,0.05307774962454346,-0.6153160198205229,0.5412829355853829,0.342355682402477,0.9585953053509725,1.103996441331084,0.619171741197861,-0.8063746087452964,0.42266415546022,-0.1619123131620609,0.42266415546022,0.13707430384263497,0.010659648604851009,1.5557134250916398,1.522027904662708,3.6549956055948876,-0.38449929077288447,-0.42998258634220327,2.976917059317765,-0.7101048204413503,-0.032043988936474706,0.13707430384263497,0.6961379107980552,-0.25000179333226685,-1.1554855115344582,-0.5684611504154431,-0.1619123131620609,-0.6625285072121776,0.2199786322467286,-0.2058028271615026,-0.6153160198205229,-0.5219578544209845,-0.2058028271615026,0.30182221516229196,-0.9041772408267448,-0.25000179333226685,0.1786609951774037,0.010659648604851009,0.13707430384263497,1.5892312826899408,0.38263514328382814,0.010659648604851009,0.657768615715268,-0.29451413807445087,3.5799366048175845,0.8099100211162025,-0.25000179333226685,-0.1619123131620609,-0.6625285072121776,-0.4758002447614249,1.419946185566603,-0.25000179333226685,1.8193146884450921,0.05307774962454346,-0.25000179333226685,-0.5219578544209845,-0.25000179333226685,5.895453047698817,-0.4758002447614249,2.669400494336479,0.46244619964697814,0.342355682402477,-0.29451413807445087,1.031696165695717,0.13707430384263497,0.46244619964697814,-0.7580513366787757,0.46244619964697814,-0.032043988936474706,1.3510176219205223,0.342355682402477,0.010659648604851009,-0.11832544439901459	3367
Nuclear pore organization	9	13	2.023416275880757	0.0430302475404891	P49790,P57740,Q9BTX1,Q92621,Q8WUM0,Q9NQC3,P52948,P12270,Q8WYP5	Processes and pathways	GO Biological process	msigdb_gobp	739,646,165,338,552,221,806,392,465	392,739,806,646,1589,882,1171,552,465,338,1523,165,221	0.7722057037721174,0.46244619964697814,0.42266415546022,0.5412829355853829,0.010659648604851009,0.38263514328382814,0.2199786322467286,0.619171741197861,0.6961379107980552,0.884673610049861,0.05307774962454346,1.4541462370669627,1.2109881782657737	3367
Outer mitochondrial membrane protein complex	7	14	2.022951471195132	0.0430781510835027	O96008,Q9BUR5,Q9Y512,Q16891,Q13505,O75431,Q9NS69	Localization	GO Cellular component	msigdb_gocc	308,203,521,650,18,443,26	443,1719,308,2666,18,650,1509,1339,1085,203,26,726,1877,521	0.6961379107980552,-0.07503752950409251,0.9217383587835264,-0.6153160198205229,4.183049042361933,0.5412829355853829,0.05307774962454346,0.13707430384263497,0.26103110464403734,1.246272443990728,3.802828202328214,0.5019846818620551,-0.11832544439901459,0.657768615715268	3367
Alpha/Beta hydrolase fold [IPR029058]	8	26	2.02189128991816	0.0431875837957453	Q8NCC3,Q9H3G5,P42785,P10619,Q9HB40,Q9H6V9,P34913,P50897	Sequence	InterPro Superfamily	interpro_homologous_superfamily	0,1,2,106,16,19,88,29	3036,149,106,3171,2659,88,2876,2,3261,1740,29,268,2480,3194,659,0,3315,3195,3025,2128,1,19,16,1536,2902,3328	-1.0035370570387363,1.5557134250916398,1.9473741733456051,-1.206907661975204,-0.6153160198205229,2.2574227850195774,-0.8063746087452964,6.292167445838333,-1.4697807385854578,-0.07503752950409251,3.679843814797915,1.031696165695717,-0.4758002447614249,-1.2587149217723634,0.5412829355853829,6.753408671655479,-1.7978135821100152,-1.2587149217723634,-0.9536627270282968,-0.25000179333226685,6.653184264123767,4.042759805139087,4.320727255133443,0.05307774962454346,-0.8063746087452964,-1.9101855426565795	3367
primary active transporter	6	16	2.016283003624624	0.0437703911567695	O96008,Q9BUN8,P60059,Q9NS69,O60888,P16615	Functions	Panther Protein class	panther_protein_class	308,407,241,26,91,211	91,2448,1719,308,1215,392,211,864,740,241,1584,2106,407,1872,847,26	2.1965207527852213,-0.4758002447614249,-0.07503752950409251,0.9217383587835264,0.1786609951774037,0.7722057037721174,1.2109881782657737,0.38263514328382814,0.46244619964697814,1.103996441331084,0.010659648604851009,-0.25000179333226685,0.7722057037721174,-0.11832544439901459,0.42266415546022,3.802828202328214	3367
Abnormal biliary tract morphology	7	25	2.0143046747968043	0.0439775554692227	Q14108,P07602,P09601,Q14739,O43933,Q9NZJ7,P04062	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,34,40,76,15,222,210	2814,15,1816,210,34,40,1647,633,3149,1062,2075,1996,287,453,32,76,1509,970,971,1694,2501,222,2946,854,1804	-0.7580513366787757,4.320727255133443,-0.11832544439901459,1.2109881782657737,3.297852942116772,3.1123997852653797,-0.032043988936474706,0.5412829355853829,-1.1554855115344582,0.26103110464403734,-0.25000179333226685,-0.2058028271615026,0.995247055805408,0.6961379107980552,3.5799366048175845,2.4369781355796594,0.05307774962454346,0.342355682402477,0.342355682402477,-0.032043988936474706,-0.4758002447614249,1.2109881782657737,-0.8550813717441338,0.42266415546022,-0.07503752950409251	3367
Hypermetropia	28	59	2.012371343879839	0.0441808069046976	Q9UJX6,Q96ST3,O14974,Q02809,Q8WWQ0,Q8WXI9,Q96L73,Q96A33,Q9H7D7,Q93008,Q71SY5,Q9Y4P3,P35222,Q96JM3,Q969N2,Q9ULH0,P27635,Q7Z5J4,A2RRP1,O00754,Q9H2P0,Q9UIG0,Q9H490,Q86V48,Q92878,Q7Z6Z7,Q9UHX1,Q15904	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	134,405,252,872,553,967,837,831,560,971,33,302,531,973,718,179,925,597,569,208,894,514,235,375,759,655,263,126	569,208,1202,252,2308,1979,2815,2383,1214,1985,1003,1821,925,531,2254,2591,1563,1066,1403,2602,1146,1405,872,1240,3284,126,2104,2019,2109,33,1023,597,655,375,1597,2846,553,967,1862,759,971,718,831,973,837,405,1526,1437,1443,894,235,560,1275,263,514,134,179,1881,302	0.580344223839915,1.2109881782657737,0.1786609951774037,1.0679451413858796,-0.38449929077288447,-0.2058028271615026,-0.7580513366787757,-0.42998258634220327,0.1786609951774037,-0.2058028271615026,0.30182221516229196,-0.11832544439901459,0.342355682402477,0.619171741197861,-0.33934491131952355,-0.5684611504154431,0.010659648604851009,0.26103110464403734,0.09521457913715693,-0.5684611504154431,0.2199786322467286,0.09521457913715693,0.38263514328382814,0.1786609951774037,-1.5776059098511652,1.7543699026919297,-0.25000179333226685,-0.2058028271615026,-0.25000179333226685,3.4530829773454683,0.30182221516229196,0.580344223839915,0.5412829355853829,0.8099100211162025,0.010659648604851009,-0.7580513366787757,0.619171741197861,0.342355682402477,-0.11832544439901459,0.46244619964697814,0.342355682402477,0.5019846818620551,0.42266415546022,0.342355682402477,0.42266415546022,0.7722057037721174,0.05307774962454346,0.09521457913715693,0.09521457913715693,0.38263514328382814,1.1398524773123389,0.619171741197861,0.1786609951774037,1.0679451413858796,0.657768615715268,1.6557714498436458,1.3855706609057188,-0.11832544439901459,0.9585953053509725	3367
Carboxylic acid transport	7	29	2.010073745441084	0.0444233843337302	P07602,P28288,P41440,P80404,Q9UBX3,P30825,Q9H2D1	Processes and pathways	GO Biological process	msigdb_gobp	34,197,102,75,142,201,123	1889,362,630,2450,1304,2316,2064,34,2384,1647,197,201,102,1141,807,2781,75,1495,1496,2188,2346,1584,1250,123,2218,1872,222,142,1285	-0.1619123131620609,0.8099100211162025,0.5412829355853829,-0.4758002447614249,0.13707430384263497,-0.38449929077288447,-0.25000179333226685,3.297852942116772,-0.42998258634220327,-0.032043988936474706,1.2813706494606423,1.246272443990728,2.0105143282367153,0.2199786322467286,0.42266415546022,-0.7101048204413503,2.4369781355796594,0.05307774962454346,0.05307774962454346,-0.29451413807445087,-0.38449929077288447,0.010659648604851009,0.1786609951774037,1.7869199137107399,-0.29451413807445087,-0.11832544439901459,1.2109881782657737,1.6225833456176855,0.1786609951774037	3367
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	8	17	2.009960386950095	0.0444353816097948	P19022,Q07065,P05067,Q08431,O43852,Q9BTY2,O76024,Q02818	Processes and pathways	Reactome Pathways	msigdb_reactome	346,225,83,243,237,153,364,93	237,364,83,921,1386,1648,2322,346,93,225,243,1497,1928,2793,1020,548,153	1.103996441331084,0.8099100211162025,2.3477816274627044,0.342355682402477,0.09521457913715693,-0.032043988936474706,-0.38449929077288447,0.8473984012280706,2.1658669221988482,1.1755156156311373,1.103996441331084,0.05307774962454346,-0.1619123131620609,-0.7101048204413503,0.30182221516229196,0.619171741197861,1.5557134250916398	3367
Gait ataxia	24	68	2.0072262855982506	0.0447255739904859	Q9NR77,Q15031,O14773,Q8IV08,Q9H7D7,P15289,P35251,P42858,P55265,Q14108,Q10713,P07602,O15118,Q96RR1,Q8IY17,Q9NZJ7,O00754,O75962,P31040,Q96CW1,P41440,P07384,P04350,P19447	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	278,397,20,151,560,633,393,265,644,32,287,34,46,721,316,222,208,573,576,761,102,240,366,483	2233,208,20,1293,46,2814,2512,573,366,240,34,2768,1310,1818,633,923,797,483,2071,1218,2872,2664,925,3010,576,393,2395,102,265,2722,1995,1829,1996,1568,644,1746,812,2091,1837,287,1497,1924,945,2186,32,1153,397,2930,2482,1338,151,316,2981,761,1094,973,721,560,278,1537,1185,1186,222,2143,774,902,3270,1289	-0.33934491131952355,1.2109881782657737,3.9953969719732,0.13707430384263497,2.8943684331092254,-0.7580513366787757,-0.5219578544209845,0.580344223839915,0.8099100211162025,1.103996441331084,3.297852942116772,-0.7101048204413503,0.13707430384263497,-0.11832544439901459,0.5412829355853829,0.342355682402477,0.42266415546022,0.657768615715268,-0.25000179333226685,0.1786609951774037,-0.8063746087452964,-0.6153160198205229,0.342355682402477,-0.9536627270282968,0.580344223839915,0.7722057037721174,-0.42998258634220327,2.0105143282367153,1.031696165695717,-0.6625285072121776,-0.2058028271615026,-0.11832544439901459,-0.2058028271615026,0.010659648604851009,0.5412829355853829,-0.07503752950409251,0.42266415546022,-0.25000179333226685,-0.11832544439901459,0.995247055805408,0.05307774962454346,-0.1619123131620609,0.342355682402477,-0.29451413807445087,3.5799366048175845,0.2199786322467286,0.7722057037721174,-0.8550813717441338,-0.4758002447614249,0.13707430384263497,1.5557134250916398,0.9217383587835264,-0.9041772408267448,0.46244619964697814,0.26103110464403734,0.342355682402477,0.5019846818620551,0.619171741197861,1.031696165695717,0.05307774962454346,0.2199786322467286,0.2199786322467286,1.2109881782657737,-0.25000179333226685,0.46244619964697814,0.38263514328382814,-1.4697807385854578,0.1786609951774037	3367
Endoplasmic reticulum golgi intermediate compartment	7	45	2.003965388330583	0.0450737681757613	P80303,O15260,P24390,Q9Y282,Q08379,Q02818,Q15904	Localization	GO Cellular component	msigdb_gocc	10,14,47,25,212,93,126	1378,14,1715,1295,2648,689,921,2958,47,2774,2328,868,1010,1906,1139,2399,869,2465,10,93,212,452,1325,585,456,1928,126,1508,3312,257,1686,665,3070,889,2034,2294,1037,1187,2047,2144,566,25,679,1199,1971	0.09521457913715693,4.34342738654226,-0.07503752950409251,0.13707430384263497,-0.6153160198205229,0.5019846818620551,0.342355682402477,-0.9041772408267448,2.8943684331092254,-0.7101048204413503,-0.38449929077288447,0.38263514328382814,0.30182221516229196,-0.1619123131620609,0.2199786322467286,-0.42998258634220327,0.38263514328382814,-0.4758002447614249,4.783524978682848,2.1658669221988482,1.2109881782657737,0.6961379107980552,0.13707430384263497,0.580344223839915,0.6961379107980552,-0.1619123131620609,1.7543699026919297,0.05307774962454346,-1.7978135821100152,1.0679451413858796,-0.032043988936474706,0.5412829355853829,-1.0035370570387363,0.38263514328382814,-0.2058028271615026,-0.33934491131952355,0.30182221516229196,0.2199786322467286,-0.2058028271615026,-0.25000179333226685,0.619171741197861,3.8271781683887824,0.5412829355853829,0.2199786322467286,-0.1619123131620609	3367
Lipid transporter activity	7	20	2.0032598252654443	0.0451494072593905	Q9BZF1,P61916,P08183,P17900,Q14849,Q9H4L5,O15118	Functions	GO Molecular function	msigdb_gomf	192,99,132,107,49,147,46	2510,46,132,1556,107,924,197,1061,2922,99,2089,49,1250,889,839,2133,192,2215,147,3296	-0.5219578544209845,2.8943684331092254,1.6557714498436458,0.010659648604851009,1.9155840365977252,0.342355682402477,1.2813706494606423,0.26103110464403734,-0.8550813717441338,2.041867375489916,-0.25000179333226685,2.8943684331092254,0.1786609951774037,0.38263514328382814,0.42266415546022,-0.25000179333226685,1.3162849902600815,-0.29451413807445087,1.5892312826899408,-1.632089162713181	3367
Clumsiness	7	22	1.99221904973822	0.0463470289838785	P07602,Q9NR77,Q9NZJ7,O14773,O75503,Q13510,O00754	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	34,278,222,20,24,90,208	208,20,1202,2814,858,24,920,34,633,576,2168,265,2091,945,90,1926,2482,824,721,278,222,774	1.2109881782657737,3.9953969719732,0.1786609951774037,-0.7580513366787757,0.38263514328382814,3.8514472696790003,0.342355682402477,3.297852942116772,0.5412829355853829,0.580344223839915,-0.29451413807445087,1.031696165695717,-0.25000179333226685,0.342355682402477,2.227038925427992,-0.1619123131620609,-0.4758002447614249,0.42266415546022,0.5019846818620551,1.031696165695717,1.2109881782657737,0.46244619964697814	3367
Intrinsic component of mitochondrial membrane	15	39	1.988883577367676	0.0467140548565332	P50416,O60830,O96008,Q9BPX6,Q9Y2R0,Q9BUR5,O14925,Q9Y512,Q16891,Q99595,Q13505,O75431,O75880,Q9HC21,Q9UG56	Localization	GO Cellular component	msigdb_gocc	579,96,308,668,110,203,623,521,650,178,18,443,481,360,361	623,858,96,443,481,1719,1304,308,1310,2666,579,1069,18,1927,750,650,1335,1509,1339,1085,1856,880,1683,178,668,203,1950,1871,1872,2368,360,2631,726,1877,361,1284,110,1289,521	0.5412829355853829,0.38263514328382814,2.0730777150539357,0.6961379107980552,0.657768615715268,-0.07503752950409251,0.13707430384263497,0.9217383587835264,0.13707430384263497,-0.6153160198205229,0.580344223839915,0.26103110464403734,4.183049042361933,-0.1619123131620609,0.46244619964697814,0.5412829355853829,0.13707430384263497,0.05307774962454346,0.13707430384263497,0.26103110464403734,-0.11832544439901459,0.38263514328382814,-0.032043988936474706,1.3855706609057188,0.5412829355853829,1.246272443990728,-0.1619123131620609,-0.11832544439901459,-0.11832544439901459,-0.38449929077288447,0.8473984012280706,-0.5684611504154431,0.5019846818620551,-0.11832544439901459,0.8473984012280706,0.1786609951774037,1.9155840365977252,0.1786609951774037,0.657768615715268	3367
Abnormality of the skull base	13	68	1.9877349691184316	0.0468410092857596	P49748,Q9UJX6,P80404,Q14739,Q9H490,Q12768,Q9UHX1,Q9NPL8,Q9Y487,Q2M1P5,O00754,O43505,Q9UBM7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	130,134,75,76,235,127,263,87,186,217,208,122,63	3184,208,1054,1202,2953,3147,122,1468,2058,2863,1379,2383,1471,1720,1057,346,1732,1559,2390,1392,2875,2591,738,3309,130,1995,805,1568,1746,2000,1911,1832,75,287,127,1238,2181,747,76,589,2347,217,2481,1935,1159,1023,1346,1423,758,1862,971,1432,1783,1606,837,765,2624,1443,1616,2899,235,87,63,263,902,134,186,3300	-1.2587149217723634,1.2109881782657737,0.26103110464403734,0.1786609951774037,-0.9041772408267448,-1.1554855115344582,1.7869199137107399,0.05307774962454346,-0.25000179333226685,-0.8063746087452964,0.09521457913715693,-0.42998258634220327,0.05307774962454346,-0.07503752950409251,0.26103110464403734,0.8473984012280706,-0.07503752950409251,0.010659648604851009,-0.42998258634220327,0.09521457913715693,-0.8063746087452964,-0.5684611504154431,0.46244619964697814,-1.7978135821100152,1.6887973998936312,-0.2058028271615026,0.42266415546022,0.010659648604851009,-0.07503752950409251,-0.2058028271615026,-0.1619123131620609,-0.11832544439901459,2.4369781355796594,0.995247055805408,1.7216629695769743,0.1786609951774037,-0.29451413807445087,0.46244619964697814,2.4369781355796594,0.580344223839915,-0.38449929077288447,1.2109881782657737,-0.4758002447614249,-0.1619123131620609,0.2199786322467286,0.30182221516229196,0.13707430384263497,0.09521457913715693,0.46244619964697814,-0.11832544439901459,0.342355682402477,0.09521457913715693,-0.07503752950409251,0.010659648604851009,0.42266415546022,0.46244619964697814,-0.5684611504154431,0.09521457913715693,0.010659648604851009,-0.8063746087452964,1.1398524773123389,2.3177928418789855,2.669400494336479,1.0679451413858796,0.38263514328382814,1.6557714498436458,1.3510176219205223,-1.686951965968084	3367
Pigment granule	10	59	1.963254057496853	0.0496166609004071	P41440,Q92820,P27105,O14773,Q92542,O43852,P02786,P11279,O00560,Q93050	Localization	GO Cellular component	msigdb_gocc	102,139,114,20,218,237,239,150,188,62	188,20,237,2648,238,239,1983,1215,2064,921,2159,2868,2710,2384,2711,1216,2712,1556,150,1986,2322,2388,1732,3086,2916,114,927,2823,1652,2718,635,102,1740,1010,2176,3155,2598,1907,740,643,742,3093,2263,2837,1832,2468,1232,1664,2096,1928,1929,1584,2020,2027,218,139,62,2033,784	1.3162849902600815,3.9953969719732,1.103996441331084,-0.6153160198205229,1.103996441331084,1.103996441331084,-0.2058028271615026,0.1786609951774037,-0.25000179333226685,0.342355682402477,-0.29451413807445087,-0.8063746087452964,-0.6625285072121776,-0.42998258634220327,-0.6625285072121776,0.1786609951774037,-0.6625285072121776,0.010659648604851009,1.5557134250916398,-0.2058028271615026,-0.38449929077288447,-0.42998258634220327,-0.07503752950409251,-1.053799466605388,-0.8550813717441338,1.8515558846925475,0.342355682402477,-0.7580513366787757,-0.032043988936474706,-0.6625285072121776,0.5412829355853829,2.0105143282367153,-0.07503752950409251,0.30182221516229196,-0.29451413807445087,-1.1554855115344582,-0.5684611504154431,-0.1619123131620609,0.46244619964697814,0.5412829355853829,0.46244619964697814,-1.053799466605388,-0.33934491131952355,-0.7580513366787757,-0.11832544439901459,-0.4758002447614249,0.1786609951774037,-0.032043988936474706,-0.25000179333226685,-0.1619123131620609,-0.1619123131620609,0.010659648604851009,-0.2058028271615026,-0.2058028271615026,1.2109881782657737,1.6225833456176855,2.669400494336479,-0.2058028271615026,0.46244619964697814	3367