diff --git "a/C028.tsv" "b/C028.tsv" new file mode 100644--- /dev/null +++ "b/C028.tsv" @@ -0,0 +1,201 @@ +term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size +Transporter activity 46 161 4.7727882574864 1.8169278581670056e-06 P13073,Q9BSK2,Q9H2V7,Q96ES6,O95202,O60830,Q8WTV0,Q9Y487,Q8TAD4,O43772,Q9NS69,P08183,Q7Z3C6,P21796,P04062,Q99595,Q9H2D1,Q14849,P45880,P51798,O14925,Q9UM00,Q8IXU6,Q7L0J3,Q9BQT8,Q9UDW1,Q7KZN9,Q6N075,Q9Y619,O43676,O00299,Q15388,Q9H936,O75964,P53985,O15118,Q03518,Q70HW3,Q9C0H2,Q9Y6M7,P30536,Q9HC21,Q9P0J0,P41440,Q9UBX3,Q9Y277 Functions GO Molecular function msigdb_gomf 253,255,271,12,262,17,18,153,280,23,24,147,278,26,158,32,35,294,38,291,169,310,48,53,56,59,192,328,72,73,198,205,78,81,82,208,87,88,94,102,100,112,249,243,259,260 1715,592,198,1762,1763,169,208,435,73,624,23,874,17,673,1344,526,323,1912,1160,2613,81,2728,1385,2935,262,3055,1388,959,158,2991,2644,1161,1962,1864,2969,147,2061,651,2396,2115,2695,527,751,253,1821,350,3096,2647,1166,3009,2649,26,2318,554,2779,752,1968,100,1866,1259,1723,1208,1091,2959,243,38,1093,2701,1262,1495,3182,1869,291,722,2168,2999,1630,82,1211,1827,1355,2554,2074,1131,3026,1733,1687,479,87,458,1640,1102,1177,294,1504,205,1835,2440,1325,328,2290,1643,2026,1589,88,192,53,278,48,2092,1796,2599,280,638,824,18,1113,793,12,2411,1372,1187,2572,32,831,664,2919,56,255,3059,698,1232,2767,94,2768,35,1852,271,78,1234,469,112,483,2873,24,1290,249,259,59,867,1710,1025,310,391,260,153,2393,72,987,102,1240 -0.0606293056858646,0.6581956434453833,1.2558874980500507,-0.08979570423491805,-0.08979570423491805,1.383857498630824,1.2182943630695027,0.8353709145003145,2.152686522096174,0.6352911062035237,3.222435477932678,0.44544306819693447,3.6453743945093926,0.5889482912953588,0.16298471623624555,0.7258739119100094,0.9822208710006587,-0.1790423277350827,0.26881271098746073,-0.7355890326334656,2.025517574520846,-0.8791073450641793,0.13593136335059053,-1.2195274337089115,1.0828619555333547,-1.5841846451243686,0.13593136335059053,0.39603391908014063,1.4545942332074184,-1.3786049993712943,-0.7710198034073763,0.26881271098746073,-0.20938691832830006,-0.14899690656748693,-1.2984677625692256,1.5065684931882488,-0.2709736160130218,0.612209574085093,-0.5292875863064875,-0.30221572716540523,-0.8427789578797747,0.7258739119100094,0.5418751241716249,1.102589523776575,-0.11924966294507812,0.9409952878769652,-1.7972452332773272,-0.7710198034073763,0.26881271098746073,-1.419122462160247,-0.7710198034073763,3.0940370861233606,-0.462913985518726,0.7034844439548688,-0.9526617479367557,0.5418751241716249,-0.20938691832830006,1.8007392900685555,-0.14899690656748693,0.21636733085825482,-0.0606293056858646,0.2427051145911597,0.3203531886001632,-1.258847985434175,1.1221876398575348,2.7295242300793277,0.3203531886001632,-0.8427789578797747,0.21636733085825482,0.08107837999042887,-3.4444654431431783,-0.14899690656748693,1.0430115443451933,0.5655044371788908,-0.3337570158659335,-1.3786049993712943,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-0.11924966294507812,0.16298471623624555,-0.6656250951850902,-0.2709736160130218,0.29469410743066005,-1.459939156603208,-0.0606293056858646,-0.031744908526115174,0.7920526088666452,1.9818952092384208,0.813790292416791,-0.0031371136066703498,0.3203531886001632,0.26881271098746073,1.0430115443451933,0.08107837999042887,1.2371500809699392,-0.11924966294507812,-0.5629231723307153,0.18979526604543842,0.9822208710006587,-0.4301759669868179,-0.0031371136066703498,-0.24003068040751657,0.025199324650836994,1.9524555180193348,1.2930133010682965,2.3661987741265276,1.063003214209736,2.492284212516803,-0.2709736160130218,-0.08979570423491805,-0.7004574638193659,1.063003214209736,0.6352911062035237,0.4940482237889104,3.4188452578218076,0.3203531886001632,0.5180573956646057,3.985962658179109,-0.5292875863064875,0.16298471623624555,0.26881271098746073,-0.6656250951850902,2.9598669449402526,0.4940482237889104,0.612209574085093,-1.1417840001131578,2.301101464563815,1.102589523776575,-1.5841846451243686,0.5889482912953588,0.2427051145911597,-0.9157349411807121,1.9077445032407137,-0.9157349411807121,2.863316355216428,-0.11924966294507812,1.0828619555333547,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,0.7920526088666452,-1.065237448909853,3.193291468873368,0.21636733085825482,1.1221876398575348,1.102589523776575,2.2746598733113577,0.4698445071041799,-0.031744908526115174,0.3710194511388473,1.0228851550061475,0.8991926986389834,1.102589523776575,1.5065684931882488,-0.49595119132772597,2.166487793701175,0.39603391908014063,1.8007392900685555,0.2427051145911597 3193 +Anion transport 24 71 4.708945884855958 2.4900116244452875e-06 Q13546,P08183,P21796,Q9H2D1,P51798,P45880,Q7L0J3,Q9NZJ7,Q9BQT8,Q6N075,P07602,Q9Y619,O00299,Q9H936,P53985,Q9C0H2,Q9Y6M7,P30536,Q9UBX3,Q9HC21,P14174,P41440,Q9UHG3,Q9Y277 Processes and pathways GO Biological process msigdb_gobp 265,147,26,35,291,38,53,321,56,328,67,72,198,78,82,94,102,100,259,112,242,243,123,260 198,1763,572,624,874,1159,346,1160,1084,1567,1161,1441,67,147,2061,2396,2695,527,751,242,26,752,100,1259,243,38,1869,291,1630,82,1681,1211,2974,1733,479,2706,265,1102,818,1504,1835,1054,328,2290,1643,53,638,824,1372,1187,664,56,698,94,2576,35,1852,78,1234,112,2106,1290,321,259,123,1025,260,2355,72,987,102 1.2558874980500507,-0.08979570423491805,0.680925878721421,0.6352911062035237,0.44544306819693447,0.26881271098746073,0.9409952878769652,0.26881271098746073,0.3203531886001632,0.025199324650836994,0.26881271098746073,0.10863077097339395,2.1802255667070183,1.5065684931882488,-0.2709736160130218,-0.5292875863064875,-0.8427789578797747,0.7258739119100094,0.5418751241716249,1.1221876398575348,3.0940370861233606,0.5418751241716249,1.8007392900685555,0.21636733085825482,1.1221876398575348,2.7295242300793277,-0.14899690656748693,1.0430115443451933,-0.0031371136066703498,2.025517574520846,-0.031744908526115174,0.2427051145911597,-1.2984677625692256,-0.0606293056858646,0.7920526088666452,-0.8427789578797747,1.0828619555333547,0.3203531886001632,0.4940482237889104,0.08107837999042887,-0.11924966294507812,0.34579373996602075,0.9822208710006587,-0.4301759669868179,-0.0031371136066703498,2.3661987741265276,0.6352911062035237,0.4940482237889104,0.16298471623624555,0.26881271098746073,0.612209574085093,2.301101464563815,0.5889482912953588,1.9077445032407137,-0.6656250951850902,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,1.7058661157411827,-0.2709736160130218,0.21636733085825482,1.0026222188239642,1.102589523776575,1.6409002994968682,0.3710194511388473,1.102589523776575,-0.462913985518726,2.166487793701175,0.39603391908014063,1.8007392900685555 3193 +SLC superfamily of solute carriers 19 44 4.216785688097684 2.478092816549093e-05 Q9BSK2,Q9H2V7,O95202,Q8TAD4,O43772,Q9H2D1,Q8IXU6,Q7L0J3,Q9Y6C9,Q9NZJ7,Q9BQT8,Q9Y619,Q9H936,P53985,Q70HW3,Q9Y6M7,Q9HC21,P41440,Q9UBX3 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 255,271,262,280,23,35,48,53,182,321,56,72,78,82,88,102,112,243,259 23,874,1160,262,1161,2061,2695,527,751,243,1630,82,1211,1733,479,1504,1835,328,2290,1643,88,53,48,280,638,1372,664,56,255,698,2768,35,1852,271,78,1234,469,112,321,259,1025,72,182,102 3.222435477932678,0.44544306819693447,0.26881271098746073,1.0828619555333547,0.26881271098746073,-0.2709736160130218,-0.8427789578797747,0.7258739119100094,0.5418751241716249,1.1221876398575348,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-0.0606293056858646,0.7920526088666452,0.08107837999042887,-0.11924966294507812,0.9822208710006587,-0.4301759669868179,-0.0031371136066703498,1.9524555180193348,2.3661987741265276,2.492284212516803,1.063003214209736,0.6352911062035237,0.16298471623624555,0.612209574085093,2.301101464563815,1.102589523776575,0.5889482912953588,-0.9157349411807121,2.863316355216428,-0.11924966294507812,1.0828619555333547,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,1.0026222188239642,1.102589523776575,0.3710194511388473,2.166487793701175,1.3478507399601813,1.8007392900685555 3193 +Receptor 10 28 4.0634032183649005 4.836237981398206e-05 Q9BUN8,Q9UQB8,Q567V2,A6NIH7,Q8WTV0,Q14108,Q9NR77,Q12959,P57105,Q13432 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 297,33,11,15,18,51,52,121,317,31 15,1624,1958,1083,2059,627,1441,1162,1773,921,317,1132,121,31,325,51,11,1219,18,1983,297,1419,52,645,799,2045,1471,33 3.752502074253957,-0.0031371136066703498,-0.20938691832830006,0.3203531886001632,-0.2709736160130218,0.6352911062035237,0.10863077097339395,0.26881271098746073,-0.08979570423491805,0.42084065117869884,1.0026222188239642,0.29469410743066005,1.6409002994968682,2.9809050828258044,0.9822208710006587,2.391845426042903,4.059893846292876,0.2427051145911597,3.4188452578218076,-0.20938691832830006,1.0430115443451933,0.13593136335059053,2.391845426042903,0.6352911062035237,0.5180573956646057,-0.24003068040751657,0.10863077097339395,2.906613677473012 3193 +Anion transmembrane transport 16 41 4.048150064941305 5.1624045030562726e-05 Q9H2D1,Q9Y6M7,P45880,P51798,Q9Y619,Q9UHG3,Q13546,Q9H936,Q9UBX3,Q9HC21,P53985,P08183,Q9BQT8,P41440,P21796,Q9Y277 Processes and pathways GO Biological process msigdb_gobp 35,102,38,291,72,123,265,78,259,112,82,147,56,243,26,260 874,346,1160,1084,1161,1441,147,2061,527,751,26,1259,243,38,1869,291,1630,82,1211,1733,479,265,1102,1835,638,824,1372,56,698,35,78,1234,112,2106,259,123,1025,260,2355,72,102 0.44544306819693447,0.9409952878769652,0.26881271098746073,0.3203531886001632,0.26881271098746073,0.10863077097339395,1.5065684931882488,-0.2709736160130218,0.7258739119100094,0.5418751241716249,3.0940370861233606,0.21636733085825482,1.1221876398575348,2.7295242300793277,-0.14899690656748693,1.0430115443451933,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-0.0606293056858646,0.7920526088666452,1.0828619555333547,0.3203531886001632,-0.11924966294507812,0.6352911062035237,0.4940482237889104,0.16298471623624555,2.301101464563815,0.5889482912953588,2.863316355216428,2.068511822464931,0.2427051145911597,1.7058661157411827,-0.2709736160130218,1.102589523776575,1.6409002994968682,0.3710194511388473,1.102589523776575,-0.462913985518726,2.166487793701175,1.8007392900685555 3193 +Peptidase activity 25 114 3.9581200776339953 7.55419806961477e-05 O75844,Q16740,Q9NZ08,P49721,P42785,P28072,Q96FW1,Q9HB40,Q9HD42,P60900,P67812,Q9Y4E8,Q9NY33,Q9UIQ6,P28070,P10619,P40818,Q9H3G5,Q5JRX3,P81605,P20618,Q6GQQ9,P55786,P28074,P42892 Functions GO Molecular function msigdb_gomf 129,3,272,8,9,20,150,22,283,30,292,173,309,47,55,60,314,83,84,92,95,355,101,105,120 1527,2050,1666,747,1909,1562,3084,129,1124,1816,1485,1719,749,2231,2797,60,452,2161,1391,2004,95,2066,2468,55,20,105,2956,2235,2697,2509,2010,314,2012,9,120,2620,1919,1446,8,1825,352,2280,2325,2999,724,2653,101,30,1097,292,92,854,2125,855,3001,928,1101,2806,1738,3,1055,1547,84,3003,355,1220,1223,2027,659,1591,2340,520,1461,1061,825,2185,1111,1279,1892,2567,150,2252,662,859,446,1373,795,738,2946,942,831,2919,943,1374,83,2742,944,1602,22,2188,283,2930,3081,1751,309,272,1521,470,47,1989,173,1663,1905,2821 0.053269504024264246,-0.2709736160130218,-0.031744908526115174,0.5418751241716249,-0.1790423277350827,0.025199324650836994,-1.7540346313524435,1.5912312904288737,0.29469410743066005,-0.11924966294507812,0.08107837999042887,-0.0606293056858646,0.5418751241716249,-0.3977371338220593,-0.9898877670258749,2.261350745716217,0.813790292416791,-0.3337570158659335,0.13593136335059053,-0.24003068040751657,1.8775608468012885,-0.2709736160130218,-0.5968579512594566,2.301101464563815,3.308198222205599,1.7694486191853893,-1.258847985434175,-0.3977371338220593,-0.8427789578797747,-0.631091924935383,-0.24003068040751657,1.0026222188239642,-0.24003068040751657,4.117747886511145,1.6409002994968682,-0.7355890326334656,-0.1790423277350827,0.10863077097339395,4.132037847844936,-0.11924966294507812,0.9409952878769652,-0.4301759669868179,-0.462913985518726,-1.3786049993712943,0.5655044371788908,-0.7710198034073763,1.8007392900685555,3.0017959971834336,0.3203531886001632,1.0430115443451933,1.9077445032407137,0.4698445071041799,-0.30221572716540523,0.4698445071041799,-1.3786049993712943,0.42084065117869884,0.3203531886001632,-0.9898877670258749,-0.0606293056858646,4.794145306453435,0.34579373996602075,0.053269504024264246,2.0110474795908226,-1.3786049993712943,0.9409952878769652,0.2427051145911597,0.2427051145911597,-0.24003068040751657,0.612209574085093,0.025199324650836994,-0.462913985518726,0.7480967979523666,0.10863077097339395,0.34579373996602075,0.4940482237889104,-0.3337570158659335,0.3203531886001632,0.21636733085825482,-0.14899690656748693,-0.6656250951850902,1.5065684931882488,-0.3977371338220593,0.612209574085093,0.4698445071041799,0.8353709145003145,0.16298471623624555,0.5180573956646057,0.5655044371788908,-1.2195274337089115,0.42084065117869884,0.4940482237889104,-1.1417840001131578,0.42084065117869884,0.16298471623624555,2.025517574520846,-0.8791073450641793,0.42084065117869884,0.025199324650836994,3.24170793389333,-0.3337570158659335,1.063003214209736,-1.1805061058028332,-1.7111232730375066,-0.0606293056858646,1.0228851550061475,1.0828619555333547,0.08107837999042887,0.813790292416791,2.5046047789471104,-0.20938691832830006,1.383857498630824,-0.0031371136066703498,-0.14899690656748693,-0.9898877670258749 3193 +Ion transmembrane transporter activity 26 99 3.9551848665459657 7.647549328204661e-05 P13073,Q96ES6,O95202,Q9Y487,Q8TAD4,O43772,P21796,Q9H2D1,P45880,P51798,Q9UM00,Q9BQT8,Q9UDW1,Q7KZN9,Q9Y619,O00299,Q9H936,O75964,P53985,Q70HW3,Q9C0H2,Q9Y6M7,Q9HC21,P41440,Q9UBX3,Q9Y277 Functions GO Molecular function msigdb_gomf 253,12,262,153,280,23,26,35,38,291,310,56,59,192,72,198,78,81,82,88,94,102,112,243,259,260 198,1763,624,23,874,1160,2613,81,262,959,2991,2644,1161,1962,1864,2969,2061,651,2396,2115,2695,527,751,253,1821,2647,1166,3009,2649,26,554,2779,1866,1259,1723,1208,2959,243,38,1093,2701,1869,291,1630,82,1211,1827,1355,2554,2074,3026,1733,1687,479,458,1102,1177,1504,1835,328,2290,1643,2026,1589,88,192,2599,280,638,824,1113,793,12,1372,1187,664,56,3059,698,94,2768,35,1852,78,1234,469,112,483,1290,259,59,1710,1025,310,260,153,72,987,102 1.2558874980500507,-0.08979570423491805,0.6352911062035237,3.222435477932678,0.44544306819693447,0.26881271098746073,-0.7355890326334656,2.025517574520846,1.0828619555333547,0.39603391908014063,-1.3786049993712943,-0.7710198034073763,0.26881271098746073,-0.20938691832830006,-0.14899690656748693,-1.2984677625692256,-0.2709736160130218,0.612209574085093,-0.5292875863064875,-0.30221572716540523,-0.8427789578797747,0.7258739119100094,0.5418751241716249,1.102589523776575,-0.11924966294507812,-0.7710198034073763,0.26881271098746073,-1.419122462160247,-0.7710198034073763,3.0940370861233606,0.7034844439548688,-0.9526617479367557,-0.14899690656748693,0.21636733085825482,-0.0606293056858646,0.2427051145911597,-1.258847985434175,1.1221876398575348,2.7295242300793277,0.3203531886001632,-0.8427789578797747,-0.14899690656748693,1.0430115443451933,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-0.11924966294507812,0.16298471623624555,-0.6656250951850902,-0.2709736160130218,-1.459939156603208,-0.0606293056858646,-0.031744908526115174,0.7920526088666452,0.813790292416791,0.3203531886001632,0.26881271098746073,0.08107837999042887,-0.11924966294507812,0.9822208710006587,-0.4301759669868179,-0.0031371136066703498,-0.24003068040751657,0.025199324650836994,1.9524555180193348,1.2930133010682965,-0.7004574638193659,1.063003214209736,0.6352911062035237,0.4940482237889104,0.3203531886001632,0.5180573956646057,3.985962658179109,0.16298471623624555,0.26881271098746073,0.612209574085093,2.301101464563815,-1.5841846451243686,0.5889482912953588,1.9077445032407137,-0.9157349411807121,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,0.7920526088666452,0.21636733085825482,1.102589523776575,2.2746598733113577,-0.031744908526115174,0.3710194511388473,1.0228851550061475,1.102589523776575,1.5065684931882488,2.166487793701175,0.39603391908014063,1.8007392900685555 3193 +Anion transmembrane transporter activity 15 46 3.818609873196536 0.0001342058081328 Q9H2D1,Q9Y6M7,P45880,P51798,Q9Y619,O00299,Q9H936,Q9UBX3,Q9HC21,P53985,Q9Y277,Q9BQT8,P41440,P21796,Q9C0H2 Functions GO Molecular function msigdb_gomf 35,102,38,291,72,198,78,259,112,82,260,56,243,26,94 198,1763,624,874,1160,1161,2061,2396,2695,527,751,26,1259,243,38,1869,291,1630,82,1211,479,1102,1504,1835,328,2290,1643,638,824,1372,1187,664,56,698,94,35,78,1234,112,1290,259,1025,260,72,987,102 1.2558874980500507,-0.08979570423491805,0.6352911062035237,0.44544306819693447,0.26881271098746073,0.26881271098746073,-0.2709736160130218,-0.5292875863064875,-0.8427789578797747,0.7258739119100094,0.5418751241716249,3.0940370861233606,0.21636733085825482,1.1221876398575348,2.7295242300793277,-0.14899690656748693,1.0430115443451933,-0.0031371136066703498,2.025517574520846,0.2427051145911597,0.7920526088666452,0.3203531886001632,0.08107837999042887,-0.11924966294507812,0.9822208710006587,-0.4301759669868179,-0.0031371136066703498,0.6352911062035237,0.4940482237889104,0.16298471623624555,0.26881271098746073,0.612209574085093,2.301101464563815,0.5889482912953588,1.9077445032407137,2.863316355216428,2.068511822464931,0.2427051145911597,1.7058661157411827,0.21636733085825482,1.102589523776575,0.3710194511388473,1.102589523776575,2.166487793701175,0.39603391908014063,1.8007392900685555 3193 +Ion transmembrane transport 33 154 3.7875015254917455 0.0001521697510451 P13073,P78417,O75844,Q96ES6,Q13546,O95202,Q8TAD4,O43772,P08183,P62942,P21796,P42858,Q9H2D1,P45880,P51798,Q16611,Q9BQT8,Q9UDW1,Q7KZN9,Q9Y619,O00299,Q9H936,O75964,P53985,Q70HW3,Q9C0H2,Q9Y6M7,P41440,Q9UBX3,Q9HC21,Q12959,Q9UHG3,Q9Y277 Processes and pathways GO Biological process msigdb_gobp 253,1,129,12,265,262,280,23,147,148,26,155,35,38,291,171,56,59,192,72,198,78,81,82,88,94,102,243,259,112,121,123,260 198,1762,1763,1247,23,874,1159,1716,346,673,2673,1344,2674,3084,1160,129,1084,2613,81,262,1817,959,2991,2644,1720,1161,1441,1962,1864,2231,2969,147,2061,651,2396,2115,1087,527,751,253,1821,2063,1771,2647,1166,3009,2649,2545,26,554,2779,577,3034,2957,2508,1866,1259,1723,1208,2959,243,155,38,1394,1395,1093,2701,559,1869,291,1630,82,2369,1211,1827,1355,2554,2074,1045,148,1,3026,1733,1687,479,1874,1359,1688,2438,121,458,265,2656,1268,1102,1177,2865,1504,2712,1835,171,2026,1589,88,192,2810,1105,2898,2961,2599,280,638,824,587,1113,12,2411,2605,1372,2946,1414,465,1894,56,2575,3059,698,94,2768,1190,35,1852,78,1234,469,112,483,2106,2847,1290,259,59,1340,123,1710,1025,1558,310,260,2355,1905,72,987,102 1.2558874980500507,-0.08979570423491805,-0.08979570423491805,0.21636733085825482,3.222435477932678,0.44544306819693447,0.26881271098746073,-0.0606293056858646,0.9409952878769652,0.5889482912953588,-0.8067497779060742,0.16298471623624555,-0.8067497779060742,-1.7540346313524435,0.26881271098746073,1.5912312904288737,0.3203531886001632,-0.7355890326334656,2.025517574520846,1.0828619555333547,-0.11924966294507812,0.39603391908014063,-1.3786049993712943,-0.7710198034073763,-0.0606293056858646,0.26881271098746073,0.10863077097339395,-0.20938691832830006,-0.14899690656748693,-0.3977371338220593,-1.2984677625692256,1.5065684931882488,-0.2709736160130218,0.612209574085093,-0.5292875863064875,-0.30221572716540523,0.3203531886001632,0.7258739119100094,0.5418751241716249,1.102589523776575,-0.11924966294507812,-0.2709736160130218,-0.08979570423491805,-0.7710198034073763,0.26881271098746073,-1.419122462160247,-0.7710198034073763,-0.6656250951850902,3.0940370861233606,0.7034844439548688,-0.9526617479367557,0.680925878721421,-1.5010550842325505,-1.258847985434175,-0.631091924935383,-0.14899690656748693,0.21636733085825482,-0.0606293056858646,0.2427051145911597,-1.258847985434175,1.1221876398575348,1.4720196860623391,2.7295242300793277,0.13593136335059053,0.13593136335059053,0.3203531886001632,-0.8427789578797747,0.7034844439548688,-0.14899690656748693,1.0430115443451933,-0.0031371136066703498,2.025517574520846,-0.49595119132772597,0.2427051145911597,-0.11924966294507812,0.16298471623624555,-0.6656250951850902,-0.2709736160130218,0.34579373996602075,1.5065684931882488,5.401623940688195,-1.459939156603208,-0.0606293056858646,-0.031744908526115174,0.7920526088666452,-0.14899690656748693,0.16298471623624555,-0.031744908526115174,-0.5629231723307153,1.6409002994968682,0.813790292416791,1.0828619555333547,-0.7710198034073763,0.21636733085825482,0.3203531886001632,0.26881271098746073,-1.065237448909853,0.08107837999042887,-0.8427789578797747,-0.11924966294507812,1.383857498630824,-0.24003068040751657,0.025199324650836994,1.9524555180193348,1.2930133010682965,-0.9898877670258749,0.3203531886001632,-1.103361115024735,-1.258847985434175,-0.7004574638193659,1.063003214209736,0.6352911062035237,0.4940482237889104,0.680925878721421,0.3203531886001632,3.985962658179109,-0.5292875863064875,-0.7004574638193659,0.16298471623624555,-1.2195274337089115,0.13593136335059053,0.813790292416791,-0.14899690656748693,2.301101464563815,-0.6656250951850902,-1.5841846451243686,0.5889482912953588,1.9077445032407137,-0.9157349411807121,0.26881271098746073,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,0.7920526088666452,-0.2709736160130218,-1.0274130001280428,0.21636733085825482,1.102589523776575,2.2746598733113577,0.18979526604543842,1.6409002994968682,-0.031744908526115174,0.3710194511388473,0.053269504024264246,1.0228851550061475,1.102589523776575,-0.462913985518726,-0.14899690656748693,2.166487793701175,0.39603391908014063,1.8007392900685555 3193 +Lysosome 20 49 3.758215908990208 0.0001711291887434 P16278,Q9Y487,P04062,P50897,O14617,Q13510,P10253,Q14108,Q9NZJ7,O75503,P10619,Q8NCC3,P07602,Q9UBR2,Q15904,O15118,P54802,P17900,O00203,P11117 Processes and pathways KEGG Pathways msigdb_kegg 263,153,158,37,415,50,303,51,321,184,60,64,67,470,460,208,339,350,472,125 472,1243,415,1666,208,624,1958,184,158,2501,996,1389,67,2645,1769,303,60,125,1915,1162,1303,2365,1672,263,350,1773,3113,37,724,339,1043,2554,1131,1635,1875,50,51,460,64,793,942,1144,321,470,1710,1293,1616,503,153 0.7920526088666452,0.21636733085825482,0.856796727704752,-0.031744908526115174,1.2182943630695027,0.6352911062035237,-0.20938691832830006,1.3296832447901088,1.4545942332074184,-0.631091924935383,0.3710194511388473,0.13593136335059053,2.1802255667070183,-0.7710198034073763,-0.08979570423491805,1.0228851550061475,2.261350745716217,1.6244355839494933,-0.1790423277350827,0.26881271098746073,0.18979526604543842,-0.49595119132772597,-0.031744908526115174,1.0828619555333547,0.9409952878769652,-0.08979570423491805,-1.928672515138034,2.8414299150165303,0.5655044371788908,0.9616792082789943,0.34579373996602075,-0.6656250951850902,0.29469410743066005,-0.0031371136066703498,-0.14899690656748693,2.4045866103244666,2.391845426042903,0.813790292416791,2.2075129346838036,0.5180573956646057,0.42084065117869884,0.29469410743066005,1.0026222188239642,0.813790292416791,-0.031744908526115174,0.21636733085825482,0.025199324650836994,0.7701555617414707,1.5065684931882488 3193 +Predicted secreted proteins 17 48 3.671791860504015 0.0002408558094739 P09429,P43490,P11047,Q9NZ08,Q15165,Q8N128,P80303,P26583,Q9HB40,O60888,P14174,Q9BTY2,O94919,P81605,Q9UMX5,Q8WUJ1,Q02818 Functions Protein Atlas Protein class protein_atlas_protein_class 312,96,349,272,10,358,46,107,22,118,242,320,275,92,29,62,63 708,1030,2113,118,394,625,275,749,1567,1720,1348,1864,312,349,242,1391,2937,107,96,1969,1783,1131,2015,46,92,2075,63,1831,535,2437,2439,1976,10,2249,358,3124,62,1649,1334,767,320,1467,2742,1070,22,272,29,2048 0.5655044371788908,0.34579373996602075,-0.30221572716540523,1.6409002994968682,0.8780699365084367,0.6352911062035237,1.063003214209736,0.5418751241716249,0.025199324650836994,-0.0606293056858646,0.16298471623624555,-0.14899690656748693,1.0026222188239642,0.9409952878769652,1.1221876398575348,0.13593136335059053,-1.2195274337089115,1.7536794627358119,1.8775608468012885,-0.20938691832830006,-0.08979570423491805,0.29469410743066005,-0.24003068040751657,2.516874712130047,1.9077445032407137,-0.2709736160130218,2.22106366880997,-0.11924966294507812,0.7258739119100094,-0.5629231723307153,-0.5629231723307153,-0.20938691832830006,4.067187229909847,-0.3977371338220593,0.9409952878769652,-2.0177869473716163,2.2345531829313767,-0.0031371136066703498,0.18979526604543842,0.5418751241716249,1.0026222188239642,0.10863077097339395,-0.8791073450641793,0.34579373996602075,3.24170793389333,1.0828619555333547,3.0328607875428633,-0.24003068040751657 3193 +Amide binding 28 100 3.658061803399122 0.0002541297746154 Q9H7Z7,P10321,Q9NZ08,Q96AY3,P24390,P00374,Q9Y680,O00505,Q8WTV0,P62942,P21796,P45880,Q9UIQ6,O43731,Q9NZJ7,Q6UX04,Q02252,P04439,P07602,Q15392,P35610,Q15388,Q03518,Q9NQX7,P55786,Q92973,P42892,P41440 Functions GO Molecular function msigdb_gomf 0,377,272,269,13,14,144,261,18,148,26,38,47,49,321,189,191,311,67,70,324,205,87,220,101,370,120,243 803,591,1526,1242,261,622,2051,1666,2694,49,712,3137,2728,14,3020,311,1033,67,750,1769,377,960,1391,2366,26,2065,2937,13,806,2547,2957,2275,324,2401,2402,1726,2855,243,120,2238,38,2430,1577,2165,2432,2279,629,1579,510,2999,101,2197,2074,2555,148,2370,1449,191,1830,87,756,3105,2127,1402,2594,2285,2128,2836,2784,205,70,1740,189,2839,937,18,2527,370,269,1846,1284,410,1414,521,3073,1374,1418,2350,0,2871,220,2043,272,321,1613,705,47,2420,2268,144 0.4940482237889104,0.6581956434453833,0.053269504024264246,0.21636733085825482,1.0828619555333547,0.6352911062035237,-0.2709736160130218,-0.031744908526115174,-0.8427789578797747,2.4299070151136095,0.5655044371788908,-2.199606848682473,-0.8791073450641793,3.902465612713916,-1.459939156603208,1.0026222188239642,0.34579373996602075,2.1802255667070183,0.5418751241716249,-0.08979570423491805,0.8991926986389834,0.39603391908014063,0.13593136335059053,-0.49595119132772597,3.0940370861233606,-0.2709736160130218,-1.2195274337089115,3.9784678086896657,0.4940482237889104,-0.6656250951850902,-1.258847985434175,-0.4301759669868179,0.9822208710006587,-0.5292875863064875,-0.5292875863064875,-0.0606293056858646,-1.065237448909853,1.1221876398575348,1.6409002994968682,-0.3977371338220593,2.7295242300793277,-0.5629231723307153,0.025199324650836994,-0.3337570158659335,-0.5629231723307153,-0.4301759669868179,0.6352911062035237,0.025199324650836994,0.7480967979523666,-1.3786049993712943,1.8007392900685555,-0.3655974840969154,-0.2709736160130218,-0.6656250951850902,1.5065684931882488,-0.49595119132772597,0.10863077097339395,1.2930133010682965,-0.11924966294507812,1.9818952092384208,0.5418751241716249,-1.8407550802597537,-0.30221572716540523,0.13593136335059053,-0.7004574638193659,-0.4301759669868179,-0.30221572716540523,-1.0274130001280428,-0.9526617479367557,1.2371500809699392,2.1802255667070183,-0.0606293056858646,1.3114045548408733,-1.0274130001280428,0.42084065117869884,3.4188452578218076,-0.631091924935383,0.9201671263885668,1.0828619555333547,-0.11924966294507812,0.21636733085825482,0.8780699365084367,0.13593136335059053,0.7480967979523666,-1.6685111568748416,0.16298471623624555,0.13593136335059053,-0.462913985518726,5.424822935915991,-1.065237448909853,1.1993188415722877,-0.24003068040751657,1.0828619555333547,1.0026222188239642,0.025199324650836994,0.5889482912953588,2.5046047789471104,-0.5292875863064875,-0.3977371338220593,1.5407221737348815 3193 +Carboxylic acid transport 11 33 3.5915173477765325 0.0003287582880406 P07602,Q9H2D1,Q9Y619,Q9H936,P53985,Q7L0J3,P14174,Q9NZJ7,P41440,Q9BQT8,Q9UBX3 Processes and pathways GO Biological process msigdb_gobp 67,35,72,78,82,53,242,321,243,56,259 1763,572,346,1160,1084,1567,1441,67,2061,242,752,1259,243,1630,82,1211,2974,479,818,1835,1643,53,824,1372,56,35,1852,78,1234,321,259,1025,72 -0.08979570423491805,0.680925878721421,0.9409952878769652,0.26881271098746073,0.3203531886001632,0.025199324650836994,0.10863077097339395,2.1802255667070183,-0.2709736160130218,1.1221876398575348,0.5418751241716249,0.21636733085825482,1.1221876398575348,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-1.2984677625692256,0.7920526088666452,0.4940482237889104,-0.11924966294507812,-0.0031371136066703498,2.3661987741265276,0.4940482237889104,0.16298471623624555,2.301101464563815,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,1.0026222188239642,1.102589523776575,0.3710194511388473,2.166487793701175 3193 +Vacuolar lumen 17 63 3.5806068965816045 0.0003427970628724 Q9H7Z7,Q9BRF8,P07602,P46976,Q8IV08,P50897,P16278,Q8NHP8,Q13510,P10253,Q14108,P54802,Q9NZJ7,Q9BTY2,P11117,P10619,P04062 Localization GO Cellular component msigdb_gocc 0,66,67,254,267,37,263,111,50,303,51,339,321,320,125,60,158 708,1243,1666,624,3092,158,2501,996,1389,1864,2362,67,2645,915,303,60,125,1255,1568,1303,2365,1672,263,350,1257,1168,1127,1091,3113,254,2433,37,2939,1782,724,881,339,2982,2885,1131,2329,1501,1734,1637,50,51,1319,267,791,111,825,2634,2143,663,942,66,320,1600,0,2816,321,1616,1902 0.5655044371788908,0.21636733085825482,-0.031744908526115174,0.6352911062035237,-1.7972452332773272,1.4545942332074184,-0.631091924935383,0.3710194511388473,0.13593136335059053,-0.14899690656748693,-0.49595119132772597,2.1802255667070183,-0.7710198034073763,0.42084065117869884,1.0228851550061475,2.261350745716217,1.6244355839494933,0.21636733085825482,0.025199324650836994,0.18979526604543842,-0.49595119132772597,-0.031744908526115174,1.0828619555333547,0.9409952878769652,0.21636733085825482,0.26881271098746073,0.29469410743066005,0.3203531886001632,-1.928672515138034,1.102589523776575,-0.5629231723307153,2.8414299150165303,-1.2195274337089115,-0.08979570423491805,0.5655044371788908,0.44544306819693447,0.9616792082789943,-1.3383867666926692,-1.103361115024735,0.29469410743066005,-0.462913985518726,0.08107837999042887,-0.0606293056858646,-0.0031371136066703498,2.4045866103244666,2.391845426042903,0.18979526604543842,1.0828619555333547,0.5180573956646057,1.7218891114806851,0.4940482237889104,-0.7355890326334656,-0.30221572716540523,0.612209574085093,0.42084065117869884,2.193900422541388,1.0026222188239642,0.025199324650836994,5.424822935915991,-0.9898877670258749,1.0026222188239642,0.025199324650836994,-0.14899690656748693 3193 +Inorganic anion transport 11 27 3.5725716871566124 0.0003534926713046 Q9Y6M7,P30536,P51798,P45880,O00299,Q9UHG3,Q9UBX3,Q9Y277,P08183,P21796,Q9C0H2 Processes and pathways GO Biological process msigdb_gobp 102,100,291,38,198,123,259,260,147,26,94 198,624,147,2396,26,100,1259,38,1869,291,1681,1211,1733,479,1504,328,824,1187,698,94,2576,1290,259,123,260,987,102 1.2558874980500507,0.6352911062035237,1.5065684931882488,-0.5292875863064875,3.0940370861233606,1.8007392900685555,0.21636733085825482,2.7295242300793277,-0.14899690656748693,1.0430115443451933,-0.031744908526115174,0.2427051145911597,-0.0606293056858646,0.7920526088666452,0.08107837999042887,0.9822208710006587,0.4940482237889104,0.26881271098746073,0.5889482912953588,1.9077445032407137,-0.6656250951850902,0.21636733085825482,1.102589523776575,1.6409002994968682,1.102589523776575,0.39603391908014063,1.8007392900685555 3193 +Lysosomal lumen 14 35 3.55812111799245 0.0003735170835459 P07602,P46976,P50897,Q8IV08,P16278,Q8NHP8,Q13510,P10253,Q14108,P54802,Q9NZJ7,P11117,P10619,P04062 Localization GO Cellular component msigdb_gocc 67,254,37,267,263,111,50,303,51,339,321,125,60,158 708,1243,1666,624,158,2501,996,1389,67,2645,915,303,60,125,1255,1303,2365,1672,263,350,1091,3113,254,37,339,1131,50,51,267,791,111,942,1600,321,1616 0.5655044371788908,0.21636733085825482,-0.031744908526115174,0.6352911062035237,1.4545942332074184,-0.631091924935383,0.3710194511388473,0.13593136335059053,2.1802255667070183,-0.7710198034073763,0.42084065117869884,1.0228851550061475,2.261350745716217,1.6244355839494933,0.21636733085825482,0.18979526604543842,-0.49595119132772597,-0.031744908526115174,1.0828619555333547,0.9409952878769652,0.3203531886001632,-1.928672515138034,1.102589523776575,2.8414299150165303,0.9616792082789943,0.29469410743066005,2.4045866103244666,2.391845426042903,1.0828619555333547,0.5180573956646057,1.7218891114806851,0.42084065117869884,0.025199324650836994,1.0026222188239642,0.025199324650836994 3193 +Intrinsic component of organelle membrane 41 124 3.554636835588433 0.0003785014994115 O75844,Q15629,P10321,O60499,O00767,Q96K12,Q9UBM7,O60830,P12235,Q99595,Q9BUN8,Q9Y282,Q13505,O43505,O14925,Q16611,Q9UM00,Q14739,Q7L0J3,P57105,P04439,Q9NQC3,O95470,Q6UXV4,P17152,Q15070,Q15388,Q5SNT2,O15118,Q03518,Q9BWH2,O15126,Q8IWA4,Q8TB61,Q9HC21,Q9Y2R0,Q86XL3,Q9P0I2,Q9GZY8,P42892,Q8TCT9 Localization GO Cellular component msigdb_gocc 129,130,377,376,506,270,141,17,527,32,297,570,166,39,169,171,310,175,53,317,311,195,574,203,200,326,205,609,208,87,482,594,233,638,112,116,494,646,247,120,520 772,1715,506,169,208,594,746,39,874,1766,376,17,2541,129,2360,1767,2728,1384,2730,574,1388,3020,311,377,527,1303,200,2647,998,2547,2399,2697,3118,120,2981,2324,1629,1781,2624,882,317,1871,2074,3026,1733,87,814,1502,166,2864,175,2202,326,1879,1179,205,130,819,171,1789,1881,2628,1883,609,1838,2026,203,1181,53,889,494,935,1224,233,2915,2563,1136,1696,3050,2599,638,520,1016,1061,1984,2032,826,270,1372,2529,1650,32,1894,2722,1514,297,1467,482,247,1114,863,1234,2667,112,2037,644,195,2873,1023,1291,1709,2495,646,1422,141,1855,2536,310,570,116,2048,1905,1476,2693 0.5180573956646057,-0.0606293056858646,0.7480967979523666,1.383857498630824,1.2182943630695027,0.6581956434453833,0.5418751241716249,2.7180994529009332,0.44544306819693447,-0.08979570423491805,0.8991926986389834,3.6453743945093926,-0.6656250951850902,1.5912312904288737,-0.49595119132772597,-0.08979570423491805,-0.8791073450641793,0.13593136335059053,-0.8791073450641793,0.680925878721421,0.13593136335059053,-1.459939156603208,1.0026222188239642,0.8991926986389834,0.7258739119100094,0.18979526604543842,1.2558874980500507,-0.7710198034073763,0.3710194511388473,-0.6656250951850902,-0.5292875863064875,-0.8427789578797747,-1.9730801058799055,1.6409002994968682,-1.3383867666926692,-0.462913985518726,-0.0031371136066703498,-0.08979570423491805,-0.7355890326334656,0.44544306819693447,1.0026222188239642,-0.14899690656748693,-0.2709736160130218,-1.459939156603208,-0.0606293056858646,1.9818952092384208,0.4940482237889104,0.08107837999042887,1.41943529737493,-1.065237448909853,1.3659083845750073,-0.3655974840969154,0.9822208710006587,-0.14899690656748693,0.26881271098746073,1.2371500809699392,1.5912312904288737,0.4940482237889104,1.383857498630824,-0.08979570423491805,-0.14899690656748693,-0.7355890326334656,-0.14899690656748693,0.6581956434453833,-0.11924966294507812,-0.24003068040751657,1.2558874980500507,0.26881271098746073,2.3661987741265276,0.44544306819693447,0.7701555617414707,0.42084065117869884,0.2427051145911597,1.1610022318711952,-1.1417840001131578,-0.6656250951850902,0.29469410743066005,-0.031744908526115174,-1.5424702465695177,-0.7004574638193659,0.6352911062035237,0.7480967979523666,0.3710194511388473,0.34579373996602075,-0.20938691832830006,-0.24003068040751657,0.4940482237889104,1.0828619555333547,0.16298471623624555,-0.631091924935383,-0.0031371136066703498,2.9598669449402526,-0.14899690656748693,-0.8427789578797747,0.08107837999042887,1.0430115443451933,0.10863077097339395,0.7920526088666452,1.1221876398575348,0.3203531886001632,0.4698445071041799,0.2427051145911597,-0.7710198034073763,1.7058661157411827,-0.24003068040751657,0.6352911062035237,1.2930133010682965,-1.065237448909853,0.3710194511388473,0.21636733085825482,-0.031744908526115174,-0.5968579512594566,0.6352911062035237,0.13593136335059053,1.5576536448951719,-0.11924966294507812,-0.631091924935383,1.0228851550061475,0.7034844439548688,1.6735598720423626,-0.24003068040751657,-0.14899690656748693,0.10863077097339395,-0.8067497779060742 3193 +Cytoprotection by hmox1 9 63 3.54060626279857 0.0003992088418456 P30519,P09601,P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 6,7,8,105,20,119,55,30,95 525,2356,1907,1762,2050,1993,417,1766,913,2360,959,7,1350,2115,253,1034,1916,1165,95,1166,2467,119,2162,2468,2400,55,20,105,6,1259,2996,1040,1628,2998,1261,1446,8,352,924,3068,30,478,1631,2434,2802,1266,1500,729,1545,1639,1584,1048,167,929,1739,1886,520,2215,795,2143,2575,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.08979570423491805,-0.2709736160130218,-0.24003068040751657,0.856796727704752,-0.08979570423491805,0.42084065117869884,-0.49595119132772597,0.39603391908014063,4.132037847844936,0.16298471623624555,-0.30221572716540523,1.102589523776575,0.34579373996602075,-0.1790423277350827,0.26881271098746073,1.8775608468012885,0.26881271098746073,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,4.195509236421808,0.21636733085825482,-1.3786049993712943,0.34579373996602075,-0.0031371136066703498,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,0.42084065117869884,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.08107837999042887,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.34579373996602075,1.41943529737493,0.42084065117869884,-0.0606293056858646,-0.14899690656748693,0.7480967979523666,-0.3655974840969154,0.5180573956646057,-0.30221572716540523,-0.6656250951850902,0.08107837999042887,0.21636733085825482 3193 +Transport of small molecules 29 147 3.536542107286813 0.0004054018701937 P30519,P09601,P49721,Q13546,O95202,Q8WTV0,Q9Y487,P28072,Q9UBV2,Q8TAD4,P08183,P21796,P60900,Q9BUN8,P45880,Q14997,P28070,O76003,Q9H936,P53985,O15118,Q70HW3,Q9C0H2,P20618,Q9Y6M7,P28074,P25787,Q9UBX3,Q9Y277 Processes and pathways Reactome Pathways msigdb_reactome 6,7,8,265,262,18,153,20,152,280,147,26,30,297,38,167,55,187,78,82,208,88,94,95,102,105,119,259,260 525,2356,1907,2050,1993,208,417,673,3084,913,187,2729,2059,262,627,749,2991,2644,1161,2000,1486,147,2061,1769,7,676,2695,527,751,2829,1821,1916,2647,1089,95,3009,2649,576,26,2467,119,2162,2468,577,2400,55,20,105,752,6,2508,3012,1259,2426,324,1207,1000,2996,1039,1208,3113,2959,1726,2998,38,1261,1446,8,352,1869,291,1731,82,2369,1211,3068,2982,2624,30,478,2554,1131,1631,2434,2802,2370,1266,2514,3026,1686,1635,729,855,2861,1545,265,1692,2656,1584,167,929,1504,1835,460,1740,1643,88,974,1105,613,2599,280,638,824,18,587,1648,793,1846,1373,795,2143,1414,831,664,1894,619,297,94,2768,1852,78,483,2873,1290,152,259,1195,1710,1558,1523,1295,744,260,153,1905,102 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3193 +Organic acid transmembrane transporter activity 7 20 3.5291650392617786 0.0004168730644757 Q9H2D1,Q9Y619,Q9H936,P53985,P08183,Q9BQT8,P41440 Functions GO Molecular function msigdb_gomf 35,72,78,82,147,56,243 1763,1160,147,2061,1259,243,1630,82,479,1835,1643,1372,56,35,1852,78,1234,259,1025,72 -0.08979570423491805,0.26881271098746073,1.5065684931882488,-0.2709736160130218,0.21636733085825482,1.1221876398575348,-0.0031371136066703498,2.025517574520846,0.7920526088666452,-0.11924966294507812,-0.0031371136066703498,0.16298471623624555,2.301101464563815,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,1.102589523776575,0.3710194511388473,2.166487793701175 3193 +transporter 19 56 3.4891905834605104 0.0004844855906855 Q9H2V7,Q567V2,Q92544,O00505,O60830,O43772,Q99595,Q9H2D1,O14617,O15397,Q9NR77,Q6N075,Q9Y619,Q15070,P53985,Q9Y5L0,Q92973,P41440,Q9HD45 Functions Panther Protein class panther_protein_class 271,11,407,261,17,23,32,35,415,416,52,328,72,326,82,222,370,243,258 1242,261,622,415,1624,416,711,624,23,712,17,2641,775,2401,2470,243,1262,2432,1579,510,2999,1630,82,1681,925,2476,2552,2074,1924,2836,326,11,328,2206,1225,2030,2251,937,407,370,2945,464,2572,32,832,664,2606,35,271,1419,258,52,1755,1558,222,72 0.21636733085825482,1.0828619555333547,0.6352911062035237,0.856796727704752,-0.0031371136066703498,0.856796727704752,0.5655044371788908,0.6352911062035237,3.222435477932678,0.5655044371788908,3.6453743945093926,-0.7710198034073763,0.5180573956646057,-0.5292875863064875,-0.5968579512594566,1.1221876398575348,0.21636733085825482,-0.5629231723307153,0.025199324650836994,0.7480967979523666,-1.3786049993712943,-0.0031371136066703498,2.025517574520846,-0.031744908526115174,0.42084065117869884,-0.5968579512594566,-0.6656250951850902,-0.2709736160130218,-0.1790423277350827,-1.0274130001280428,0.9822208710006587,4.059893846292876,0.9822208710006587,-0.3655974840969154,0.2427051145911597,-0.24003068040751657,-0.3977371338220593,0.42084065117869884,0.8780699365084367,0.9201671263885668,-1.2195274337089115,0.813790292416791,-0.6656250951850902,2.9598669449402526,0.4940482237889104,0.612209574085093,-0.7004574638193659,2.863316355216428,1.0828619555333547,0.13593136335059053,1.102589523776575,2.391845426042903,-0.0606293056858646,0.053269504024264246,1.1993188415722877,2.166487793701175 3193 +Receptor 8 34 3.4849546405724223 0.0004922204748938 P24390,Q14739,Q8WTV0,O43731,Q14108,O15118,Q9NS69,Q99720 Functions Protein Atlas Molecular function protein_atlas_molecular_function 13,175,18,49,51,208,24,57 1526,1030,208,435,49,749,1441,236,2001,2994,1443,1914,1915,1162,1391,1773,13,1000,2015,2439,51,175,2081,1835,342,18,1936,1113,1414,57,24,2154,1812,2850 0.053269504024264246,0.34579373996602075,1.2182943630695027,0.8353709145003145,2.4299070151136095,0.5418751241716249,0.10863077097339395,1.1416579910536835,-0.24003068040751657,-1.3786049993712943,0.10863077097339395,-0.1790423277350827,-0.1790423277350827,0.26881271098746073,0.13593136335059053,-0.08979570423491805,3.9784678086896657,0.3710194511388473,-0.24003068040751657,-0.5629231723307153,2.391845426042903,1.3659083845750073,-0.2709736160130218,-0.11924966294507812,0.9616792082789943,3.4188452578218076,-0.1790423277350827,0.3203531886001632,0.13593136335059053,2.2879099390267865,3.193291468873368,-0.30221572716540523,-0.08979570423491805,-1.0274130001280428 3193 +Transmembrane transport 47 211 3.474835157317425 0.0005111673625006 P13073,P78417,O75844,Q15629,Q9BSK2,Q9H2V7,Q96ES6,Q13546,O95202,O60830,Q8WTV0,Q8TAD4,O43772,Q9NS69,P08183,P62942,P21796,P42858,P04062,Q99595,Q9H2D1,P45880,P51798,O14925,Q16611,Q8IXU6,Q7L0J3,Q9BQT8,Q9UDW1,Q7KZN9,Q9Y619,O00299,Q15388,Q9H936,O75964,P53985,Q03518,Q70HW3,Q9C0H2,Q9Y6M7,P41440,Q9UBX3,Q9HC21,P23786,Q12959,Q9UHG3,Q9Y277 Processes and pathways GO Biological process msigdb_gobp 253,1,129,130,255,271,12,265,262,17,18,280,23,24,147,148,26,155,158,32,35,38,291,169,171,48,53,56,59,192,72,198,205,78,81,82,87,88,94,102,243,259,112,113,121,123,260 1715,2876,198,1762,1763,169,711,1247,23,874,1159,1716,17,346,673,2673,1344,2674,1083,3084,1160,129,1084,2613,81,2728,262,1817,713,1388,959,158,2991,2644,1720,1161,1441,2114,1962,1864,2231,2731,2969,147,2061,651,2396,2115,3041,2695,1489,1087,527,751,253,1821,2063,1771,2647,1166,3009,2649,2545,26,113,554,2779,577,3034,752,2957,2508,529,1866,3108,1259,1723,1208,1091,2959,243,155,38,1394,1395,1093,2701,1495,1129,2324,559,1869,291,2882,1630,82,2369,1211,1827,1355,2859,2197,2554,2074,1045,148,1,3026,1733,1687,479,87,1874,2739,1359,1688,2438,121,458,265,2656,1268,1102,1177,2865,1504,2712,205,130,1835,635,171,759,2084,2560,2290,1643,2026,1589,2630,88,192,53,3049,2810,48,1105,2898,2811,2961,1796,2599,280,638,2136,824,18,587,1113,12,2411,2605,1372,1650,2946,32,1414,831,664,465,1894,56,2575,255,3059,698,1945,1232,94,2768,1190,35,1852,271,78,1234,2668,469,112,483,2106,2847,2873,24,1290,259,59,867,1340,123,1710,1025,1558,569,310,260,2355,1905,72,987,102 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3193 +SLC25 family of mitochondrial transporters 10 21 3.4700015791024423 0.0005204553049991 Q9BSK2,Q9H2D1,Q9Y619,Q9H936,Q9HC21,Q9Y6C9,O43772,Q9BQT8,Q70HW3,Q9UBX3 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 255,35,72,78,112,182,23,56,88,259 23,874,1160,1161,527,751,1630,1733,479,2290,88,56,255,35,78,112,321,259,1025,72,182 3.222435477932678,0.44544306819693447,0.26881271098746073,0.26881271098746073,0.7258739119100094,0.5418751241716249,-0.0031371136066703498,-0.0606293056858646,0.7920526088666452,-0.4301759669868179,1.9524555180193348,2.301101464563815,1.102589523776575,2.863316355216428,2.068511822464931,1.7058661157411827,1.0026222188239642,1.102589523776575,0.3710194511388473,2.166487793701175,1.3478507399601813 3193 +Mitochondrial carrier domain superfamily [IPR023395] 10 21 3.4700015791024423 0.0005204553049991 Q9BSK2,Q9H2D1,Q9Y619,Q9H936,Q9HC21,Q9Y6C9,O43772,Q9BQT8,Q70HW3,Q9UBX3 Sequence InterPro Superfamily interpro_homologous_superfamily 255,35,72,78,112,182,23,56,88,259 23,874,1160,1161,527,751,1630,1733,479,2290,88,56,255,35,78,112,321,259,1025,72,182 3.222435477932678,0.44544306819693447,0.26881271098746073,0.26881271098746073,0.7258739119100094,0.5418751241716249,-0.0031371136066703498,-0.0606293056858646,0.7920526088666452,-0.4301759669868179,1.9524555180193348,2.301101464563815,1.102589523776575,2.863316355216428,2.068511822464931,1.7058661157411827,1.0026222188239642,1.102589523776575,0.3710194511388473,2.166487793701175,1.3478507399601813 3193 +Mitochondrial substrate/solute carrier [IPR018108] 10 21 3.4700015791024423 0.0005204553049991 Q9BSK2,Q9H2D1,Q9Y619,Q9H936,Q9HC21,Q9Y6C9,O43772,Q9BQT8,Q70HW3,Q9UBX3 Sequence InterPro Repeat interpro_repeat 255,35,72,78,112,182,23,56,88,259 23,874,1160,1161,527,751,1630,1733,479,2290,88,56,255,35,78,112,321,259,1025,72,182 3.222435477932678,0.44544306819693447,0.26881271098746073,0.26881271098746073,0.7258739119100094,0.5418751241716249,-0.0031371136066703498,-0.0606293056858646,0.7920526088666452,-0.4301759669868179,1.9524555180193348,2.301101464563815,1.102589523776575,2.863316355216428,2.068511822464931,1.7058661157411827,1.0026222188239642,1.102589523776575,0.3710194511388473,2.166487793701175,1.3478507399601813 3193 +Molecular transducer activity 9 31 3.462461120000917 0.0005352592426948 Q9BUN8,Q15629,P30536,Q8WTV0,Q14108,Q5KU26,O15118,Q99720,Q4VCS5 Functions GO Molecular function msigdb_gomf 297,130,100,18,51,342,208,57,28 1030,208,435,1441,1914,1162,1773,100,1040,921,1577,1449,2706,1132,2439,51,2081,130,1835,28,342,1219,18,1936,1113,1650,57,297,1947,1422,867 0.34579373996602075,1.2182943630695027,0.8353709145003145,0.10863077097339395,-0.1790423277350827,0.26881271098746073,-0.08979570423491805,1.8007392900685555,0.34579373996602075,0.42084065117869884,0.025199324650836994,0.10863077097339395,-0.8427789578797747,0.29469410743066005,-0.5629231723307153,2.391845426042903,-0.2709736160130218,1.5912312904288737,-0.11924966294507812,3.0328607875428633,0.9616792082789943,0.2427051145911597,3.4188452578218076,-0.1790423277350827,0.3203531886001632,-0.0031371136066703498,2.2879099390267865,1.0430115443451933,-0.1790423277350827,0.13593136335059053,0.4698445071041799 3193 +Endopeptidase activity 13 61 3.462216860995565 0.0005357452858762 O75844,Q16740,P67812,Q9NZ08,P49721,P28074,Q9Y4E8,P28072,Q5JRX3,P28070,P42892,P60900,P20618 Functions GO Molecular function msigdb_gomf 129,3,292,272,8,105,173,20,84,55,120,30,95 1666,1909,1562,3084,129,2231,2161,1391,2004,95,2066,2468,55,20,105,2235,2697,2010,314,2012,120,2620,1919,1446,8,2280,2325,724,2653,30,292,855,928,1101,2806,3,1055,84,3003,1591,520,1461,1061,1111,1279,1892,662,446,1373,795,942,831,2919,1374,272,1521,470,1989,173,1663,1905 -0.031744908526115174,-0.1790423277350827,0.025199324650836994,-1.7540346313524435,1.5912312904288737,-0.3977371338220593,-0.3337570158659335,0.13593136335059053,-0.24003068040751657,1.8775608468012885,-0.2709736160130218,-0.5968579512594566,2.301101464563815,3.308198222205599,1.7694486191853893,-0.3977371338220593,-0.8427789578797747,-0.24003068040751657,1.0026222188239642,-0.24003068040751657,1.6409002994968682,-0.7355890326334656,-0.1790423277350827,0.10863077097339395,4.132037847844936,-0.4301759669868179,-0.462913985518726,0.5655044371788908,-0.7710198034073763,3.0017959971834336,1.0430115443451933,0.4698445071041799,0.42084065117869884,0.3203531886001632,-0.9898877670258749,4.794145306453435,0.34579373996602075,2.0110474795908226,-1.3786049993712943,0.025199324650836994,0.7480967979523666,0.10863077097339395,0.34579373996602075,0.3203531886001632,0.21636733085825482,-0.14899690656748693,0.612209574085093,0.8353709145003145,0.16298471623624555,0.5180573956646057,0.42084065117869884,0.4940482237889104,-1.1417840001131578,0.16298471623624555,1.0828619555333547,0.08107837999042887,0.813790292416791,-0.20938691832830006,1.383857498630824,-0.0031371136066703498,-0.14899690656748693 3193 +Tetrapyrrole binding 11 16 3.46098743061063 0.0005381979402858 Q9H7Z7,Q7KZN9,P30519,P09601,Q9NRV9,O43169,Q99707,P53701,Q6UW02,Q16850,Q8WUJ1 Functions GO Molecular function msigdb_gomf 0,192,6,7,109,45,308,363,442,93,62 1526,435,45,651,7,1967,6,363,93,442,192,62,1282,308,0,109 0.053269504024264246,0.8353709145003145,2.516874712130047,0.612209574085093,4.132037847844936,-0.20938691832830006,4.195509236421808,0.9201671263885668,1.9077445032407137,0.8353709145003145,1.2930133010682965,2.2345531829313767,0.21636733085825482,1.0228851550061475,5.424822935915991,1.7536794627358119 3193 +Sphingolipid metabolic process 10 26 3.439756117297581 0.0005822385950002 Q8NCC3,P07602,P50897,Q96G23,P16278,Q06136,Q13510,Q9NZJ7,Q16880,P04062 Processes and pathways GO Biological process msigdb_gobp 64,67,37,41,263,16,50,321,188,158 1668,1381,1909,574,158,996,1389,67,2645,263,350,2318,1536,37,16,50,188,2628,64,41,832,1235,1709,321,2495,2691 -0.031744908526115174,0.13593136335059053,-0.1790423277350827,0.680925878721421,1.4545942332074184,0.3710194511388473,0.13593136335059053,2.1802255667070183,-0.7710198034073763,1.0828619555333547,0.9409952878769652,-0.462913985518726,0.053269504024264246,2.8414299150165303,3.703535835976282,2.4045866103244666,1.3114045548408733,-0.7355890326334656,2.2075129346838036,2.671958061458734,0.4940482237889104,0.2427051145911597,-0.031744908526115174,1.0026222188239642,-0.5968579512594566,-0.8067497779060742 3193 +Mitotic g1 phase and g1 s transition 35 78 3.4174446605514808 0.000632119436065 Q13416,P49721,Q99436,P00374,Q9UBD5,P28072,P35244,O00231,P31751,P09884,P06400,P60900,Q14566,P24941,Q99741,O43242,O75419,P28070,Q9NRF9,Q06323,Q9Y619,P14635,Q9NR33,Q7L590,P11802,P20618,P49642,P51665,P61289,P33991,Q07864,P28074,P31350,P06493,P25787 Processes and pathways Reactome Pathways msigdb_reactome 632,8,795,14,800,20,397,525,529,777,277,30,293,422,697,417,301,55,588,729,72,209,221,216,215,95,598,352,478,719,225,105,718,236,119 525,2356,1907,2050,1993,417,906,301,913,14,1203,277,236,777,2733,215,2828,209,1163,1916,95,422,781,2467,119,2162,2468,1676,2400,55,20,105,1536,1537,718,529,719,1627,1038,397,2996,1209,2998,1261,598,1311,1446,8,1494,352,3068,30,478,1631,2434,2802,1872,1266,1634,729,225,1545,1639,632,3120,1584,293,929,216,795,2143,697,221,588,800,1523,1295,72 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.0228851550061475,0.42084065117869884,3.902465612713916,0.2427051145911597,1.063003214209736,1.1416579910536835,0.5180573956646057,-0.8791073450641793,1.1993188415722877,-1.0274130001280428,1.2182943630695027,0.26881271098746073,-0.1790423277350827,1.8775608468012885,0.856796727704752,0.5180573956646057,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.031744908526115174,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.053269504024264246,0.053269504024264246,0.5655044371788908,0.7258739119100094,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.6581956434453833,0.18979526604543842,0.10863077097339395,4.132037847844936,0.08107837999042887,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.14899690656748693,0.21636733085825482,-0.0031371136066703498,0.5655044371788908,1.1802219848882647,0.053269504024264246,-0.0031371136066703498,0.6352911062035237,-1.9730801058799055,0.025199324650836994,1.0430115443451933,0.42084065117869884,1.1993188415722877,0.5180573956646057,-0.30221572716540523,0.5889482912953588,1.1993188415722877,0.680925878721421,0.5180573956646057,0.08107837999042887,0.21636733085825482,2.166487793701175 3193 +Lipid localization 20 69 3.403330932036937 0.0006656959782707 P09455,Q9H2V7,P35790,Q8WTV0,O43772,P08183,Q7Z3C6,Q9BQE5,P04062,Q14849,Q14108,Q9NZJ7,Q99720,P07602,P35610,Q9H6V9,O15118,P30536,P23786,P14174 Processes and pathways GO Biological process msigdb_gobp 128,271,145,18,23,147,278,27,158,294,51,321,57,67,324,80,208,100,113,242 772,2051,208,804,23,874,597,995,2587,550,1533,3066,158,1567,1864,67,2645,2314,147,128,2695,242,2677,350,2318,2065,113,752,100,529,3108,1259,324,145,1262,2324,1131,1686,2739,51,1320,294,1740,1365,1643,278,935,3124,18,2411,57,27,2722,1467,1232,2767,2531,271,546,80,2458,321,2691,1120,801,1558,1426,1294,2693 0.5180573956646057,-0.2709736160130218,1.2182943630695027,0.4940482237889104,3.222435477932678,0.44544306819693447,0.6581956434453833,0.3710194511388473,-0.7004574638193659,0.7034844439548688,0.053269504024264246,-1.6685111568748416,1.4545942332074184,0.025199324650836994,-0.14899690656748693,2.1802255667070183,-0.7710198034073763,-0.462913985518726,1.5065684931882488,1.6078795867372875,-0.8427789578797747,1.1221876398575348,-0.8067497779060742,0.9409952878769652,-0.462913985518726,-0.2709736160130218,1.6735598720423626,0.5418751241716249,1.8007392900685555,0.7258739119100094,-1.8845641737373735,0.21636733085825482,0.9822208710006587,1.5236941588049682,0.21636733085825482,-0.462913985518726,0.29469410743066005,-0.031744908526115174,-0.8791073450641793,2.391845426042903,0.18979526604543842,1.0430115443451933,-0.0606293056858646,0.16298471623624555,-0.0031371136066703498,1.063003214209736,0.42084065117869884,-2.0177869473716163,3.4188452578218076,-0.5292875863064875,2.2879099390267865,3.0940370861233606,-0.8427789578797747,0.10863077097339395,0.2427051145911597,-0.9157349411807121,-0.631091924935383,1.0828619555333547,0.7258739119100094,2.0399178851551123,-0.5629231723307153,1.0026222188239642,-0.8067497779060742,0.3203531886001632,0.5180573956646057,0.053269504024264246,0.13593136335059053,0.21636733085825482,-0.8067497779060742 3193 +Membrane lipid metabolic process 11 34 3.349933271860096 0.0008083103022749 Q8NCC3,P07602,P50897,Q8NBX0,Q96G23,P16278,Q06136,Q13510,Q9NZJ7,Q16880,P04062 Processes and pathways GO Biological process msigdb_gobp 64,67,37,133,41,263,16,50,321,188,158 1668,1381,1909,2056,574,158,2501,996,1389,67,2645,263,350,2318,1536,37,16,50,188,2628,133,64,1061,1984,41,2529,521,832,863,1235,1709,321,2495,2691 -0.031744908526115174,0.13593136335059053,-0.1790423277350827,-0.2709736160130218,0.680925878721421,1.4545942332074184,-0.631091924935383,0.3710194511388473,0.13593136335059053,2.1802255667070183,-0.7710198034073763,1.0828619555333547,0.9409952878769652,-0.462913985518726,0.053269504024264246,2.8414299150165303,3.703535835976282,2.4045866103244666,1.3114045548408733,-0.7355890326334656,1.574489660490009,2.2075129346838036,0.34579373996602075,-0.20938691832830006,2.671958061458734,-0.631091924935383,0.7480967979523666,0.4940482237889104,0.4698445071041799,0.2427051145911597,-0.031744908526115174,1.0026222188239642,-0.5968579512594566,-0.8067497779060742 3193 +Biliary tract abnormality 10 26 3.333293830593396 0.0008582425229084 P07602,P09601,Q9UJW0,O95202,Q14739,Q14108,P54098,Q9Y5L0,P14174,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 67,7,240,262,175,51,85,222,242,158 624,262,1818,914,158,67,7,242,2365,2366,2010,578,2167,85,855,2478,51,175,1838,1279,2298,2264,321,240,1198,222 0.6352911062035237,1.0828619555333547,-0.11924966294507812,0.42084065117869884,1.4545942332074184,2.1802255667070183,4.132037847844936,1.1221876398575348,-0.49595119132772597,-0.49595119132772597,-0.24003068040751657,0.680925878721421,-0.3337570158659335,1.9965069209559112,0.4698445071041799,-0.5968579512594566,2.391845426042903,1.3659083845750073,-0.11924966294507812,0.21636733085825482,-0.4301759669868179,-0.3977371338220593,1.0026222188239642,1.1416579910536835,0.26881271098746073,1.1993188415722877 3193 +Nucleophile aminohydrolases, N-terminal [IPR029055] 7 18 3.2997232259259883 0.0009678022451871 P49721,P28074,P28072,P28070,P25787,P60900,P20618 Sequence InterPro Superfamily interpro_homologous_superfamily 8,105,20,55,119,30,95 1993,214,95,2467,119,2162,2468,2400,55,20,105,1446,8,30,2372,1971,1223,795 -0.24003068040751657,1.1993188415722877,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.10863077097339395,4.132037847844936,3.0017959971834336,-0.49595119132772597,-0.20938691832830006,0.2427051145911597,0.5180573956646057 3193 +Proteasome, subunit alpha/beta [IPR001353] 6 14 3.2946549678981785 0.0009854259294761 P49721,P28074,P28072,P28070,P60900,P20618 Sequence InterPro Family interpro_family 8,105,20,55,30,95 1993,95,2467,119,2162,2468,2400,55,20,105,1446,8,30,795 -0.24003068040751657,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.10863077097339395,4.132037847844936,3.0017959971834336,0.5180573956646057 3193 +Proteasome core complex 6 14 3.2946549678981785 0.0009854259294761 P49721,P28074,P28072,P28070,P60900,P20618 Localization GO Cellular component msigdb_gocc 8,105,20,55,30,95 1993,95,2467,119,2162,2468,2400,55,20,105,1446,8,30,795 -0.24003068040751657,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.10863077097339395,4.132037847844936,3.0017959971834336,0.5180573956646057 3193 +Mitochondrial transmembrane transport 13 51 3.290594465917672 0.0009997592728927 Q99595,Q9BSK2,Q9H2D1,Q9Y619,O14925,Q15388,Q9H936,O60830,O75964,P23786,O43772,Q9BQT8,P21796 Processes and pathways GO Biological process msigdb_gobp 32,255,35,72,169,205,78,17,81,113,23,56,26 169,711,23,17,673,3084,1160,2613,81,2728,262,713,1388,1161,1962,3041,527,751,26,113,554,2779,1723,2701,2324,1630,1827,1355,1733,205,2084,2560,2026,1105,2811,2599,2136,587,1372,32,1894,56,255,35,78,1234,2668,1025,1558,1905,72 1.383857498630824,0.5655044371788908,3.222435477932678,3.6453743945093926,0.5889482912953588,-1.7540346313524435,0.26881271098746073,-0.7355890326334656,2.025517574520846,-0.8791073450641793,1.0828619555333547,0.5655044371788908,0.13593136335059053,0.26881271098746073,-0.20938691832830006,-1.5424702465695177,0.7258739119100094,0.5418751241716249,3.0940370861233606,1.6735598720423626,0.7034844439548688,-0.9526617479367557,-0.0606293056858646,-0.8427789578797747,-0.462913985518726,-0.0031371136066703498,-0.11924966294507812,0.16298471623624555,-0.0606293056858646,1.2371500809699392,-0.2709736160130218,-0.6656250951850902,-0.24003068040751657,0.3203531886001632,-0.9898877670258749,-0.7004574638193659,-0.30221572716540523,0.680925878721421,0.16298471623624555,2.9598669449402526,-0.14899690656748693,2.301101464563815,1.102589523776575,2.863316355216428,2.068511822464931,0.2427051145911597,-0.7710198034073763,0.3710194511388473,0.053269504024264246,-0.14899690656748693,2.166487793701175 3193 +Organic anion transmembrane transporter activity 8 29 3.279931208229845 0.0010383240110132 Q9H2D1,Q9Y6M7,Q9Y619,Q9H936,Q9HC21,P53985,Q9BQT8,P41440 Functions GO Molecular function msigdb_gomf 35,102,72,78,112,82,56,243 1763,874,1160,1161,2061,2695,527,751,1259,243,1630,82,479,1102,1835,2290,1643,638,1372,664,56,35,78,1234,112,259,1025,72,102 -0.08979570423491805,0.44544306819693447,0.26881271098746073,0.26881271098746073,-0.2709736160130218,-0.8427789578797747,0.7258739119100094,0.5418751241716249,0.21636733085825482,1.1221876398575348,-0.0031371136066703498,2.025517574520846,0.7920526088666452,0.3203531886001632,-0.11924966294507812,-0.4301759669868179,-0.0031371136066703498,0.6352911062035237,0.16298471623624555,0.612209574085093,2.301101464563815,2.863316355216428,2.068511822464931,0.2427051145911597,1.7058661157411827,1.102589523776575,0.3710194511388473,2.166487793701175,1.8007392900685555 3193 +Transporter 58 182 3.2785551859475515 0.0010433996054877 Q9BSK2,O00629,O60499,Q12907,Q9H2V7,P52294,Q92544,Q96ES6,P24390,Q9P2W9,O95202,O00505,Q9Y487,Q8TAD4,O43772,P08183,Q9BQE5,O60749,P12235,Q9H2D1,Q96FZ7,Q8IXU6,O43731,O95721,O14617,Q7L0J3,Q9Y6C9,P24539,Q9BQT8,Q9NZJ7,Q6N075,Q9Y619,Q15070,Q9HC07,Q15388,Q9H936,P53985,Q9Y5L0,Q03518,Q70HW3,Q9Y296,Q02978,O95487,P17900,Q9Y6M7,O15400,O60664,Q13190,O00203,Q92973,Q8TB61,Q8WUX9,Q9HC21,Q96A65,Q9HD45,P41440,Q9UBX3,Q9UNK0 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 255,622,376,631,271,510,407,12,13,414,262,261,153,280,23,147,27,274,527,35,566,48,49,302,415,53,182,554,56,321,328,72,326,469,205,78,82,222,87,88,485,479,213,350,102,595,597,226,472,370,638,639,112,388,258,243,259,124 2463,2876,472,1665,261,622,2747,415,2158,595,49,1296,23,874,376,597,712,274,1299,673,843,1160,2613,1301,262,1386,3019,995,213,302,1388,2991,2644,1161,1962,147,2061,1769,2695,1915,527,751,1303,1821,350,2647,3009,2649,13,554,2779,752,2163,1259,920,1723,2470,2959,243,1094,1262,961,1495,1781,1497,1579,510,1630,2368,1783,1731,82,1870,1681,2369,2550,1211,2476,1827,1043,1355,2552,2554,2074,1003,2370,3026,1733,1635,682,479,87,1875,2405,1924,2707,631,226,2128,2374,2287,2836,1504,326,1322,2712,2019,205,1835,328,2290,1643,88,53,2206,935,48,1225,1136,2030,280,1227,638,2251,937,639,1935,407,370,793,388,1371,2945,12,566,1372,1185,2214,2572,832,664,27,56,2606,255,2790,2349,698,2768,1652,35,1852,271,78,1234,469,112,258,2873,321,1556,2691,837,414,1988,1660,259,1710,1152,1755,1025,124,1808,485,2111,745,153,222,72,904,182,102 -0.5968579512594566,-1.103361115024735,0.7920526088666452,-0.031744908526115174,1.0828619555333547,0.6352911062035237,-0.9157349411807121,0.856796727704752,-0.3337570158659335,0.6581956434453833,2.4299070151136095,0.18979526604543842,3.222435477932678,0.44544306819693447,0.8991926986389834,0.6581956434453833,0.5655044371788908,1.063003214209736,0.18979526604543842,0.5889482912953588,0.4698445071041799,0.26881271098746073,-0.7355890326334656,0.18979526604543842,1.0828619555333547,0.13593136335059053,-1.459939156603208,0.3710194511388473,1.1993188415722877,1.0228851550061475,0.13593136335059053,-1.3786049993712943,-0.7710198034073763,0.26881271098746073,-0.20938691832830006,1.5065684931882488,-0.2709736160130218,-0.08979570423491805,-0.8427789578797747,-0.1790423277350827,0.7258739119100094,0.5418751241716249,0.18979526604543842,-0.11924966294507812,0.9409952878769652,-0.7710198034073763,-1.419122462160247,-0.7710198034073763,3.9784678086896657,0.7034844439548688,-0.9526617479367557,0.5418751241716249,-0.3337570158659335,0.21636733085825482,0.42084065117869884,-0.0606293056858646,-0.5968579512594566,-1.258847985434175,1.1221876398575348,0.3203531886001632,0.21636733085825482,0.39603391908014063,0.08107837999042887,-0.08979570423491805,0.08107837999042887,0.025199324650836994,0.7480967979523666,-0.0031371136066703498,-0.49595119132772597,-0.08979570423491805,-0.0606293056858646,2.025517574520846,-0.14899690656748693,-0.031744908526115174,-0.49595119132772597,-0.6656250951850902,0.2427051145911597,-0.5968579512594566,-0.11924966294507812,0.34579373996602075,0.16298471623624555,-0.6656250951850902,-0.6656250951850902,-0.2709736160130218,0.3710194511388473,-0.49595119132772597,-1.459939156603208,-0.0606293056858646,-0.0031371136066703498,0.5889482912953588,0.7920526088666452,1.9818952092384208,-0.14899690656748693,-0.5292875863064875,-0.1790423277350827,-0.8427789578797747,0.6352911062035237,1.1802219848882647,-0.30221572716540523,-0.49595119132772597,-0.4301759669868179,-1.0274130001280428,0.08107837999042887,0.9822208710006587,0.18979526604543842,-0.8427789578797747,-0.24003068040751657,1.2371500809699392,-0.11924966294507812,0.9822208710006587,-0.4301759669868179,-0.0031371136066703498,1.9524555180193348,2.3661987741265276,-0.3655974840969154,0.42084065117869884,2.492284212516803,0.2427051145911597,0.29469410743066005,-0.24003068040751657,1.063003214209736,0.2427051145911597,0.6352911062035237,-0.3977371338220593,0.42084065117869884,0.6352911062035237,-0.1790423277350827,0.8780699365084367,0.9201671263885668,0.5180573956646057,0.8991926986389834,0.16298471623624555,-1.2195274337089115,3.985962658179109,0.7034844439548688,0.16298471623624555,0.26881271098746073,-0.3655974840969154,-0.6656250951850902,0.4940482237889104,0.612209574085093,3.0940370861233606,2.301101464563815,-0.7004574638193659,1.102589523776575,-0.9526617479367557,-0.462913985518726,0.5889482912953588,-0.9157349411807121,-0.0031371136066703498,2.863316355216428,-0.11924966294507812,1.0828619555333547,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,1.102589523776575,-1.065237448909853,1.0026222188239642,0.053269504024264246,-0.8067497779060742,0.4940482237889104,0.8780699365084367,-0.20938691832830006,-0.0031371136066703498,1.102589523776575,-0.031744908526115174,0.29469410743066005,-0.0606293056858646,0.3710194511388473,1.6409002994968682,-0.08979570423491805,0.7920526088666452,-0.2709736160130218,0.5655044371788908,1.5065684931882488,1.1993188415722877,2.166487793701175,0.44544306819693447,1.3478507399601813,1.8007392900685555 3193 +Protease 19 85 3.2323332688519995 0.0012278376505552 O75844,Q16740,Q9NZ08,P42785,P28072,Q96FW1,Q9HB40,P67812,Q9Y4E8,Q9NY33,Q9UIQ6,P10619,P40818,Q9H3G5,Q5JRX3,P81605,P55786,P28074,P42892 Functions Protein Atlas Molecular function protein_atlas_molecular_function 129,3,272,9,20,150,22,292,173,309,47,60,314,83,84,92,101,105,120 1527,2050,1666,1909,1562,3084,129,1124,1485,1719,2231,2797,60,452,1391,2004,20,105,2956,2235,2010,314,2012,9,120,2620,1919,1825,2280,2325,2999,724,2653,101,1097,292,92,854,2125,928,1101,2806,1738,3,1055,84,3003,355,1223,659,1591,520,1061,1111,1279,1892,150,2252,662,859,446,1373,795,2946,942,831,1374,83,2742,944,1602,22,2930,3081,1751,309,272,1521,470,47,1989,173,1663,1905,2821 0.053269504024264246,-0.2709736160130218,-0.031744908526115174,-0.1790423277350827,0.025199324650836994,-1.7540346313524435,1.5912312904288737,0.29469410743066005,0.08107837999042887,-0.0606293056858646,-0.3977371338220593,-0.9898877670258749,2.261350745716217,0.813790292416791,0.13593136335059053,-0.24003068040751657,3.308198222205599,1.7694486191853893,-1.258847985434175,-0.3977371338220593,-0.24003068040751657,1.0026222188239642,-0.24003068040751657,4.117747886511145,1.6409002994968682,-0.7355890326334656,-0.1790423277350827,-0.11924966294507812,-0.4301759669868179,-0.462913985518726,-1.3786049993712943,0.5655044371788908,-0.7710198034073763,1.8007392900685555,0.3203531886001632,1.0430115443451933,1.9077445032407137,0.4698445071041799,-0.30221572716540523,0.42084065117869884,0.3203531886001632,-0.9898877670258749,-0.0606293056858646,4.794145306453435,0.34579373996602075,2.0110474795908226,-1.3786049993712943,0.9409952878769652,0.2427051145911597,0.612209574085093,0.025199324650836994,0.7480967979523666,0.34579373996602075,0.3203531886001632,0.21636733085825482,-0.14899690656748693,1.5065684931882488,-0.3977371338220593,0.612209574085093,0.4698445071041799,0.8353709145003145,0.16298471623624555,0.5180573956646057,-1.2195274337089115,0.42084065117869884,0.4940482237889104,0.16298471623624555,2.025517574520846,-0.8791073450641793,0.42084065117869884,0.025199324650836994,3.24170793389333,-1.1805061058028332,-1.7111232730375066,-0.0606293056858646,1.0228851550061475,1.0828619555333547,0.08107837999042887,0.813790292416791,2.5046047789471104,-0.20938691832830006,1.383857498630824,-0.0031371136066703498,-0.14899690656748693,-0.9898877670258749 3193 +Organic acid transmembrane transport 9 29 3.2313722163235923 0.0012319739519415 Q9H2D1,Q9Y619,Q9H936,P53985,O43772,P23786,P08183,Q9BQT8,P41440 Processes and pathways GO Biological process msigdb_gobp 35,72,78,82,23,113,147,56,243 23,346,1160,1084,1441,147,2061,2695,113,752,529,3108,1259,243,2324,1630,82,479,1835,824,1372,56,35,1852,78,1234,259,1025,72 3.222435477932678,0.9409952878769652,0.26881271098746073,0.3203531886001632,0.10863077097339395,1.5065684931882488,-0.2709736160130218,-0.8427789578797747,1.6735598720423626,0.5418751241716249,0.7258739119100094,-1.8845641737373735,0.21636733085825482,1.1221876398575348,-0.462913985518726,-0.0031371136066703498,2.025517574520846,0.7920526088666452,-0.11924966294507812,0.4940482237889104,0.16298471623624555,2.301101464563815,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,1.102589523776575,0.3710194511388473,2.166487793701175 3193 +Sterol metabolic process 15 40 3.1887978055403163 0.0014286576774931 P48449,Q14849,Q15392,Q15036,Q9UBM7,P35610,Q9UKR5,Q14739,Q8WTV0,O15118,Q16850,Q9BQE5,P34913,P42765,P04062 Processes and pathways GO Biological process msigdb_gobp 99,294,70,367,141,324,143,175,18,208,93,27,190,61,158 208,1564,2729,3092,507,158,1720,1087,2397,2507,3102,190,324,1573,3113,61,99,2165,1782,2511,1131,1686,2516,1641,1320,175,294,367,1879,1834,70,1880,381,93,1740,18,27,141,1120,143 1.2182943630695027,0.025199324650836994,-0.8791073450641793,-1.7972452332773272,0.7480967979523666,1.4545942332074184,-0.0606293056858646,0.3203531886001632,-0.5292875863064875,-0.631091924935383,-1.8407550802597537,1.2930133010682965,0.9822208710006587,0.025199324650836994,-1.928672515138034,2.2345531829313767,1.8317054739763257,-0.3337570158659335,-0.08979570423491805,-0.631091924935383,0.29469410743066005,-0.031744908526115174,-0.631091924935383,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,0.9201671263885668,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,-0.14899690656748693,0.8991926986389834,1.9077445032407137,-0.0606293056858646,3.4188452578218076,3.0940370861233606,1.5576536448951719,0.3203531886001632,1.5407221737348815 3193 +Abnormal biliary tract morphology 9 23 3.1852942971461697 0.0014460686777961 P07602,P09601,Q9UJW0,Q14739,Q14108,P54098,Q9Y5L0,P14174,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 67,7,240,175,51,85,222,242,158 624,914,158,67,7,242,2365,2366,2010,578,2167,85,855,51,175,1838,1279,2298,2264,321,240,1198,222 0.6352911062035237,0.42084065117869884,1.4545942332074184,2.1802255667070183,4.132037847844936,1.1221876398575348,-0.49595119132772597,-0.49595119132772597,-0.24003068040751657,0.680925878721421,-0.3337570158659335,1.9965069209559112,0.4698445071041799,2.391845426042903,1.3659083845750073,-0.11924966294507812,0.21636733085825482,-0.4301759669868179,-0.3977371338220593,1.0026222188239642,1.1416579910536835,0.26881271098746073,1.1993188415722877 3193 +Glycosyltransferase 8 31 3.165695198005699 0.0015471281789432 P43490,O43505,Q2TAA5,Q16880,Q9BV10,O15294,Q9BT22,P04062 Functions Protein Atlas Molecular function protein_atlas_molecular_function 96,39,108,188,115,174,91,158 174,39,2113,2056,1347,1534,158,1085,1487,1390,2776,1568,2317,1776,96,1171,2372,814,379,188,108,1459,2789,2600,1413,91,115,230,947,1423,2157 1.3659083845750073,2.7180994529009332,-0.30221572716540523,-0.2709736160130218,0.16298471623624555,0.053269504024264246,1.4545942332074184,0.3203531886001632,0.08107837999042887,0.13593136335059053,-0.9526617479367557,0.025199324650836994,-0.462913985518726,-0.08979570423491805,1.8775608468012885,0.26881271098746073,-0.49595119132772597,0.4940482237889104,0.8991926986389834,1.3114045548408733,1.7536794627358119,0.10863077097339395,-0.9526617479367557,-0.7004574638193659,0.13593136335059053,1.9227226839549494,1.6735598720423626,1.1802219848882647,0.42084065117869884,0.13593136335059053,-0.30221572716540523 3193 +Secondary alcohol metabolic process 16 44 3.15579726681968 0.0016006007063757 P48449,Q14849,P48735,Q15392,Q15036,Q9UBM7,P35610,O75874,Q14739,Q8WTV0,O15118,Q16850,Q9BQE5,P34913,P42765,P04062 Processes and pathways GO Biological process msigdb_gobp 99,294,90,70,367,141,324,136,175,18,208,93,27,190,61,158 208,2054,1564,136,2729,3092,507,158,1720,1087,2397,2507,3102,190,324,1573,61,99,90,2165,3025,2621,1782,2511,1131,1686,2516,1641,1320,175,294,367,1879,1834,70,1880,381,93,1740,18,2985,27,141,1120 1.2182943630695027,-0.2709736160130218,0.025199324650836994,1.5576536448951719,-0.8791073450641793,-1.7972452332773272,0.7480967979523666,1.4545942332074184,-0.0606293056858646,0.3203531886001632,-0.5292875863064875,-0.631091924935383,-1.8407550802597537,1.2930133010682965,0.9822208710006587,0.025199324650836994,2.2345531829313767,1.8317054739763257,1.9227226839549494,-0.3337570158659335,-1.459939156603208,-0.7355890326334656,-0.08979570423491805,-0.631091924935383,0.29469410743066005,-0.031744908526115174,-0.631091924935383,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,0.9201671263885668,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,-0.14899690656748693,0.8991926986389834,1.9077445032407137,-0.0606293056858646,3.4188452578218076,-1.3383867666926692,3.0940370861233606,1.5576536448951719,0.3203531886001632 3193 +Lytic vacuole organization 12 24 3.145734760082257 0.0016567017640687 P50897,O95295,O00203,Q8N511,Q9HC07,Q14457,Q14108,P10253,P54802,O75503,P11117,P04062 Processes and pathways GO Biological process msigdb_gobp 37,347,472,139,469,493,51,303,339,184,125,158 472,1666,184,347,158,2645,303,125,530,37,1629,339,965,2405,51,493,1365,139,1371,1185,469,2458,837,1856 0.7920526088666452,-0.031744908526115174,1.3296832447901088,0.9409952878769652,1.4545942332074184,-0.7710198034073763,1.0228851550061475,1.6244355839494933,0.7258739119100094,2.8414299150165303,-0.0031371136066703498,0.9616792082789943,0.39603391908014063,-0.5292875863064875,2.391845426042903,0.7701555617414707,0.16298471623624555,1.5576536448951719,0.16298471623624555,0.26881271098746073,0.813790292416791,-0.5629231723307153,0.4940482237889104,-0.11924966294507812 3193 +Organic anion transport 13 45 3.124998343451882 0.0017780606112745 P07602,Q9H2D1,Q9Y6M7,Q9Y619,Q9H936,Q9HC21,P53985,Q7L0J3,P14174,Q9NZJ7,P41440,Q9BQT8,Q9UBX3 Processes and pathways GO Biological process msigdb_gobp 67,35,102,72,78,112,82,53,242,321,243,56,259 1763,572,874,346,1160,1084,1567,1161,1441,67,2061,2695,527,751,242,752,1259,243,1630,82,1211,2974,479,2706,1102,818,1835,2290,1643,53,638,824,1372,664,56,35,1852,78,1234,112,321,259,1025,72,102 -0.08979570423491805,0.680925878721421,0.44544306819693447,0.9409952878769652,0.26881271098746073,0.3203531886001632,0.025199324650836994,0.26881271098746073,0.10863077097339395,2.1802255667070183,-0.2709736160130218,-0.8427789578797747,0.7258739119100094,0.5418751241716249,1.1221876398575348,0.5418751241716249,0.21636733085825482,1.1221876398575348,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-1.2984677625692256,0.7920526088666452,-0.8427789578797747,0.3203531886001632,0.4940482237889104,-0.11924966294507812,-0.4301759669868179,-0.0031371136066703498,2.3661987741265276,0.6352911062035237,0.4940482237889104,0.16298471623624555,0.612209574085093,2.301101464563815,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,1.7058661157411827,1.0026222188239642,1.102589523776575,0.3710194511388473,2.166487793701175,1.8007392900685555 3193 +Dna replication pre initiation 31 66 3.120597131593491 0.0018048476478513 Q13416,P49721,Q99436,P52294,Q9UBD5,P28072,P35244,O00231,P09884,P60900,Q14566,Q14997,P24941,O43242,Q99741,O75419,P28070,Q9NRF9,Q06323,Q9Y619,Q9NR33,Q7L590,O60684,P20618,P49642,P51665,P61289,P33991,Q07864,P28074,P25787 Processes and pathways Reactome Pathways msigdb_reactome 632,8,795,510,800,20,397,525,777,30,293,167,422,417,697,301,55,588,729,72,221,216,712,95,598,352,478,719,225,105,119 525,2356,1907,2050,1993,417,906,712,301,913,777,1163,3067,1916,95,422,781,2467,119,2162,2468,1676,2400,55,20,105,719,1627,1038,397,2996,2998,1261,598,1311,1446,8,1494,352,510,3068,30,478,1631,2434,2802,2803,1685,729,225,1545,632,293,2836,167,929,216,795,2143,697,221,588,800,1523,1295,72 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.5655044371788908,1.0228851550061475,0.42084065117869884,0.5180573956646057,0.26881271098746073,-1.6685111568748416,-0.1790423277350827,1.8775608468012885,0.856796727704752,0.5180573956646057,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.031744908526115174,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.6581956434453833,0.18979526604543842,0.10863077097339395,4.132037847844936,0.08107837999042887,0.9409952878769652,0.7480967979523666,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.9898877670258749,-0.031744908526115174,0.5655044371788908,1.1802219848882647,0.053269504024264246,0.6352911062035237,1.0430115443451933,-1.0274130001280428,1.41943529737493,0.42084065117869884,1.1993188415722877,0.5180573956646057,-0.30221572716540523,0.5889482912953588,1.1993188415722877,0.680925878721421,0.5180573956646057,0.08107837999042887,0.21636733085825482,2.166487793701175 3193 +Activation of the pre replicative complex 15 23 3.096700502335024 0.0019568747385489 P49642,P33991,Q07864,Q13416,Q9NRF9,Q9Y619,P24941,Q9UBD5,Q99741,O75419,P35244,Q9NR33,P09884,Q7L590,Q14566 Processes and pathways Reactome Pathways msigdb_reactome 598,719,225,632,588,72,422,800,697,301,397,221,777,216,293 906,301,777,1163,422,781,1676,719,1627,1038,397,598,1311,1494,225,632,293,216,697,221,588,800,72 0.42084065117869884,1.0228851550061475,0.5180573956646057,0.26881271098746073,0.856796727704752,0.5180573956646057,-0.031744908526115174,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,0.6581956434453833,0.18979526604543842,0.08107837999042887,1.1802219848882647,0.6352911062035237,1.0430115443451933,1.1993188415722877,0.5889482912953588,1.1993188415722877,0.680925878721421,0.5180573956646057,2.166487793701175 3193 +serine protease 6 18 3.0965608596981102 0.0019577966873685 Q16740,P42785,Q9H3G5,Q9HB40,O95870,P10619 Functions Panther Protein class panther_protein_class 3,9,83,22,276,60 1666,1909,276,60,2193,2161,2235,2010,9,1919,292,3,1055,976,2344,83,22,2901 -0.031744908526115174,-0.1790423277350827,1.063003214209736,2.261350745716217,-0.3655974840969154,-0.3337570158659335,-0.3977371338220593,-0.24003068040751657,4.117747886511145,-0.1790423277350827,1.0430115443451933,4.794145306453435,0.34579373996602075,0.39603391908014063,-0.462913985518726,2.025517574520846,3.24170793389333,-1.103361115024735 3193 +Organic acid transport 12 45 3.037154917402592 0.0023882268104113 P09455,Q9H2D1,P41440,Q9Y619,Q9H936,P53985,O43772,Q7L0J3,P23786,P08183,Q9BQT8,P14174 Processes and pathways GO Biological process msigdb_gobp 128,35,243,72,78,82,23,53,113,147,56,242 1763,572,23,874,346,1160,1084,2587,3066,1567,1441,2314,147,2061,128,2695,242,113,752,529,3108,1259,243,2324,1630,82,1211,2974,479,818,1835,1643,2026,53,824,1372,56,35,1852,78,1234,259,1025,1426,72 -0.08979570423491805,0.680925878721421,3.222435477932678,0.44544306819693447,0.9409952878769652,0.26881271098746073,0.3203531886001632,-0.7004574638193659,-1.6685111568748416,0.025199324650836994,0.10863077097339395,-0.462913985518726,1.5065684931882488,-0.2709736160130218,1.6078795867372875,-0.8427789578797747,1.1221876398575348,1.6735598720423626,0.5418751241716249,0.7258739119100094,-1.8845641737373735,0.21636733085825482,1.1221876398575348,-0.462913985518726,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-1.2984677625692256,0.7920526088666452,0.4940482237889104,-0.11924966294507812,-0.0031371136066703498,-0.24003068040751657,2.3661987741265276,0.4940482237889104,0.16298471623624555,2.301101464563815,2.863316355216428,-0.11924966294507812,2.068511822464931,0.2427051145911597,1.102589523776575,0.3710194511388473,0.13593136335059053,2.166487793701175 3193 +Secondary active transmembrane transporter activity 9 22 3.023882906677722 0.002495530057839 Q9Y6M7,P51798,Q96ES6,Q9H936,O95202,P53985,P41440,Q9UBX3,Q02978 Functions GO Molecular function msigdb_gomf 102,291,12,78,262,82,243,259,479 262,1161,2061,527,751,243,1869,291,1630,82,1211,1733,479,1504,1835,2599,12,698,1852,78,259,102 1.0828619555333547,0.26881271098746073,-0.2709736160130218,0.7258739119100094,0.5418751241716249,1.1221876398575348,-0.14899690656748693,1.0430115443451933,-0.0031371136066703498,2.025517574520846,0.2427051145911597,-0.0606293056858646,0.7920526088666452,0.08107837999042887,-0.11924966294507812,-0.7004574638193659,3.985962658179109,0.5889482912953588,-0.11924966294507812,2.068511822464931,1.102589523776575,1.8007392900685555 3193 +Blood vessel endothelial cell migration 6 21 2.9948301145576792 0.0027459773577809 P14923,P09601,P42785,Q8WTV0,P04792,Q4VCS5 Processes and pathways GO Biological process msigdb_gobp 290,7,9,18,185,28 1122,1030,625,1567,185,1441,1962,312,7,290,1771,2779,1260,9,922,2780,1500,635,28,2288,18 0.29469410743066005,0.34579373996602075,0.6352911062035237,0.025199324650836994,1.3296832447901088,0.10863077097339395,-0.20938691832830006,1.0026222188239642,4.132037847844936,1.0430115443451933,-0.08979570423491805,-0.9526617479367557,0.21636733085825482,4.117747886511145,0.42084065117869884,-0.9526617479367557,0.08107837999042887,0.6352911062035237,3.0328607875428633,-0.4301759669868179,3.4188452578218076 3193 +Inorganic anion transmembrane transporter activity 8 21 2.963108748519129 0.0030454895287379 Q9Y6M7,P51798,P45880,O00299,Q9UBX3,Q9Y277,P21796,Q9C0H2 Functions GO Molecular function msigdb_gomf 102,291,38,198,259,260,26,94 198,624,2396,26,1259,38,1869,291,1211,479,1504,328,824,1187,698,94,1290,259,260,987,102 1.2558874980500507,0.6352911062035237,-0.5292875863064875,3.0940370861233606,0.21636733085825482,2.7295242300793277,-0.14899690656748693,1.0430115443451933,0.2427051145911597,0.7920526088666452,0.08107837999042887,0.9822208710006587,0.4940482237889104,0.26881271098746073,0.5889482912953588,1.9077445032407137,0.21636733085825482,1.102589523776575,1.102589523776575,0.39603391908014063,1.8007392900685555 3193 +Sphingolipid metabolism in senescence 8 12 2.958513060608809 0.003091271419175 Q96G23,P24941,P16278,Q06136,Q13510,P06400,P11802,P04062 Processes and pathways WikiPathways msigdb_wp 41,422,263,16,50,277,215,158 1668,158,2114,277,215,263,422,1168,530,16,50,41 -0.031744908526115174,1.4545942332074184,-0.30221572716540523,1.063003214209736,1.1993188415722877,1.0828619555333547,0.856796727704752,0.26881271098746073,0.7258739119100094,3.703535835976282,2.4045866103244666,2.671958061458734 3193 +Inorganic molecular entity transmembrane transporter activity 22 74 2.9358338717305528 0.0033265242064643 P13073,Q96ES6,O95202,Q9Y487,Q8TAD4,P21796,P51798,P45880,Q9UM00,Q9UDW1,Q7KZN9,Q6N075,Q9HC07,O00299,Q13423,Q9H936,O75964,Q9HD20,Q9C0H2,Q9Y6M7,Q9UBX3,Q9Y277 Functions GO Molecular function msigdb_gomf 253,12,262,153,280,26,291,38,310,59,192,328,469,198,458,78,81,483,94,102,259,260 198,624,2613,81,262,959,2991,2644,1161,1962,1864,2969,2061,651,2396,2115,527,253,1821,2647,1166,3009,2649,26,554,2779,1866,1259,1723,1208,2959,38,1093,2701,1869,291,1211,1827,1355,2554,2074,3026,1733,1687,479,458,1504,328,1589,192,2599,280,824,1113,793,12,1187,831,698,94,2768,1852,78,469,483,1290,259,59,1710,310,260,153,987,102 1.2558874980500507,0.6352911062035237,-0.7355890326334656,2.025517574520846,1.0828619555333547,0.39603391908014063,-1.3786049993712943,-0.7710198034073763,0.26881271098746073,-0.20938691832830006,-0.14899690656748693,-1.2984677625692256,-0.2709736160130218,0.612209574085093,-0.5292875863064875,-0.30221572716540523,0.7258739119100094,1.102589523776575,-0.11924966294507812,-0.7710198034073763,0.26881271098746073,-1.419122462160247,-0.7710198034073763,3.0940370861233606,0.7034844439548688,-0.9526617479367557,-0.14899690656748693,0.21636733085825482,-0.0606293056858646,0.2427051145911597,-1.258847985434175,2.7295242300793277,0.3203531886001632,-0.8427789578797747,-0.14899690656748693,1.0430115443451933,0.2427051145911597,-0.11924966294507812,0.16298471623624555,-0.6656250951850902,-0.2709736160130218,-1.459939156603208,-0.0606293056858646,-0.031744908526115174,0.7920526088666452,0.813790292416791,0.08107837999042887,0.9822208710006587,0.025199324650836994,1.2930133010682965,-0.7004574638193659,1.063003214209736,0.4940482237889104,0.3203531886001632,0.5180573956646057,3.985962658179109,0.26881271098746073,0.4940482237889104,0.5889482912953588,1.9077445032407137,-0.9157349411807121,-0.11924966294507812,2.068511822464931,0.813790292416791,0.7920526088666452,0.21636733085825482,1.102589523776575,2.2746598733113577,-0.031744908526115174,1.0228851550061475,1.102589523776575,1.5065684931882488,0.39603391908014063,1.8007392900685555 3193 +Mitochondrial transport 21 86 2.889876840927562 0.0038539278171132 O14737,Q8N4H5,O60830,O43772,Q9NS69,Q99595,Q14849,P45880,O14925,Q16611,Q96EK5,P42765,Q15388,O75964,Q5JRX3,P30536,P55786,Q9P0J0,P23786,Q9GZY8,Q9UBX3 Processes and pathways GO Biological process msigdb_gobp 252,142,17,23,24,32,294,38,169,171,186,61,205,81,84,100,101,249,113,247,259 1619,1430,252,169,1909,711,23,17,2541,3084,2613,81,2728,2730,2642,395,1346,713,1388,2773,1161,1962,915,2363,3041,527,1165,113,554,2779,2957,361,100,2618,1723,61,38,2701,578,961,1129,2324,1781,2882,101,1827,1355,1213,855,294,326,205,1788,171,2560,2628,84,2290,1460,2915,2563,142,2811,587,2032,186,1185,738,32,831,247,2668,2873,24,249,1521,2743,259,984,1025,1558,1198,2820,1476,2393,802 -0.0031371136066703498,0.10863077097339395,1.102589523776575,1.383857498630824,-0.1790423277350827,0.5655044371788908,3.222435477932678,3.6453743945093926,-0.6656250951850902,-1.7540346313524435,-0.7355890326334656,2.025517574520846,-0.8791073450641793,-0.8791073450641793,-0.7710198034073763,0.8780699365084367,0.16298471623624555,0.5655044371788908,0.13593136335059053,-0.9526617479367557,0.26881271098746073,-0.20938691832830006,0.42084065117869884,-0.49595119132772597,-1.5424702465695177,0.7258739119100094,0.26881271098746073,1.6735598720423626,0.7034844439548688,-0.9526617479367557,-1.258847985434175,0.9201671263885668,1.8007392900685555,-0.7355890326334656,-0.0606293056858646,2.2345531829313767,2.7295242300793277,-0.8427789578797747,0.680925878721421,0.39603391908014063,0.29469410743066005,-0.462913985518726,-0.08979570423491805,-1.103361115024735,1.8007392900685555,-0.11924966294507812,0.16298471623624555,0.2427051145911597,0.4698445071041799,1.0430115443451933,0.9822208710006587,1.2371500809699392,-0.08979570423491805,1.383857498630824,-0.6656250951850902,-0.7355890326334656,2.0110474795908226,-0.4301759669868179,0.10863077097339395,-1.1417840001131578,-0.6656250951850902,1.5407221737348815,-0.9898877670258749,0.680925878721421,-0.24003068040751657,1.3296832447901088,0.26881271098746073,0.5655044371788908,2.9598669449402526,0.4940482237889104,1.1221876398575348,-0.7710198034073763,-1.065237448909853,3.193291468873368,1.1221876398575348,0.08107837999042887,-0.8791073450641793,1.102589523776575,0.39603391908014063,0.3710194511388473,0.053269504024264246,0.26881271098746073,-0.9898877670258749,0.10863077097339395,-0.49595119132772597,0.5180573956646057 3193 +Retrograde transport endosome to golgi 20 32 2.8863084743257192 0.0038978990744549 O60499,P53367,Q9UID3,Q9C0C9,Q4KMP7,O60493,O60749,O60271,O15498,O75503,O15260,Q8IWJ2,P49257,Q9Y5X3,Q8IUD2,O75436,Q13190,P40616,Q9P2D3,Q14203 Processes and pathways GO Biological process msigdb_gobp 376,137,801,1067,541,774,274,907,286,184,804,462,961,872,357,843,226,488,250,758 804,286,907,774,376,274,843,184,1386,488,961,1629,137,1635,226,2374,758,1055,541,357,462,1699,1892,1185,2349,1067,250,1151,1660,801,1237,872 0.4940482237889104,1.0430115443451933,0.42084065117869884,0.5180573956646057,0.8991926986389834,1.063003214209736,0.4698445071041799,1.3296832447901088,0.13593136335059053,0.7701555617414707,0.39603391908014063,-0.0031371136066703498,1.5576536448951719,-0.0031371136066703498,1.1802219848882647,-0.49595119132772597,0.5418751241716249,0.34579373996602075,0.7258739119100094,0.9409952878769652,0.813790292416791,-0.031744908526115174,-0.14899690656748693,0.26881271098746073,-0.462913985518726,0.34579373996602075,1.1221876398575348,0.29469410743066005,-0.0031371136066703498,0.5180573956646057,0.2427051145911597,0.4698445071041799 3193 +Reductase 6 15 2.8823994938535717 0.0039465901726543 Q9H7Z7,Q15392,Q9UBM7,P00374,Q14739,Q9UDW1 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 0,70,141,14,175,59 3008,187,1385,14,2003,2505,2116,2005,718,175,70,2975,0,141,59 -1.419122462160247,1.3114045548408733,0.13593136335059053,3.902465612713916,-0.24003068040751657,-0.631091924935383,-0.30221572716540523,-0.24003068040751657,0.5655044371788908,1.3659083845750073,2.1802255667070183,-1.2984677625692256,5.424822935915991,1.5576536448951719,2.2746598733113577 3193 +S phase 38 97 2.874381337309688 0.0040481985806235 Q13416,P49721,Q99436,Q9UBD5,P28072,P35244,O00231,P31751,P09884,P06400,P60900,Q14566,Q14997,P24941,Q99741,O43242,O75419,P28070,P35251,Q9NRF9,Q06323,Q9Y619,Q15054,Q9NR33,P18858,P11802,P20618,P49642,P51665,P61289,P33991,Q07864,P28074,Q16763,P25787,P41440,Q9Y2S7,Q9H1A4 Processes and pathways Reactome Pathways msigdb_reactome 632,8,795,800,20,397,525,529,777,277,30,293,167,422,697,417,301,55,555,588,729,72,459,221,716,215,95,598,352,478,719,225,105,368,119,243,648,522 525,2356,1907,2050,1993,417,906,2358,301,913,277,777,215,2828,1163,1916,716,95,422,781,2467,119,2162,2468,1676,2400,55,20,105,1258,1865,529,719,1627,1038,397,2958,2698,555,2996,2322,1678,2236,243,2998,1261,2702,598,1311,1446,8,1494,352,3068,30,478,1631,2434,2802,1266,729,225,1008,1545,1639,632,1584,293,2129,971,167,929,459,368,886,1013,1368,795,2143,697,861,1287,522,221,588,1519,800,2109,1807,1522,2537,1523,1295,1903,1028,648,72 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3193 +Regulation of hmox1 expression and activity 8 45 2.8694361351102406 0.004112043644473 P09601,P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 7,8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,7,1916,1165,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,1500,729,1545,1639,1584,1048,167,929,520,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,4.132037847844936,-0.1790423277350827,0.26881271098746073,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.08107837999042887,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.34579373996602075,1.41943529737493,0.42084065117869884,0.7480967979523666,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Apc c mediated degradation of cell cycle proteins 18 59 2.863700188717376 0.0041872413007764 P51665,Q14997,P49721,P28074,P61289,P24941,Q9H1A4,Q16763,Q12834,P06493,O43242,P14635,P28072,P25787,P28070,P06400,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 352,167,8,105,478,422,522,368,457,236,417,209,20,119,55,277,30,95 525,2356,1907,2050,1993,2422,417,2933,1669,913,277,236,209,1916,95,422,2467,119,2162,2468,2400,55,20,105,1865,2996,2998,1261,1446,8,352,723,3068,30,478,1631,2434,2802,1266,729,457,1008,1545,815,1639,1584,167,929,368,2297,795,2143,522,2109,1807,1522,2537,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,-0.5629231723307153,0.856796727704752,-1.2195274337089115,-0.031744908526115174,0.42084065117869884,1.063003214209736,1.1416579910536835,1.2182943630695027,-0.1790423277350827,1.8775608468012885,0.856796727704752,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.14899690656748693,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,0.5655044371788908,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.813790292416791,0.3710194511388473,0.053269504024264246,0.4940482237889104,-0.0031371136066703498,0.025199324650836994,1.41943529737493,0.42084065117869884,0.9201671263885668,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.7480967979523666,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.21636733085825482 3193 +Hexosyltransferase activity 8 32 2.832882388471502 0.0046130355241458 Q9H488,O43505,Q2TAA5,Q16880,Q9BV10,O15294,Q9BT22,P04062 Functions GO Molecular function msigdb_gomf 230,39,108,188,115,174,91,158 2421,174,39,2113,2056,1563,158,1819,1440,1085,1389,2645,1568,2317,1776,254,1171,2242,814,379,188,108,658,1459,2789,2600,1413,91,115,230,947,2157 -0.5629231723307153,1.3659083845750073,2.7180994529009332,-0.30221572716540523,-0.2709736160130218,0.025199324650836994,1.4545942332074184,-0.11924966294507812,0.10863077097339395,0.3203531886001632,0.13593136335059053,-0.7710198034073763,0.025199324650836994,-0.462913985518726,-0.08979570423491805,1.102589523776575,0.26881271098746073,-0.3977371338220593,0.4940482237889104,0.8991926986389834,1.3114045548408733,1.7536794627358119,0.612209574085093,0.10863077097339395,-0.9526617479367557,-0.7004574638193659,0.13593136335059053,1.9227226839549494,1.6735598720423626,1.1802219848882647,0.42084065117869884,-0.30221572716540523 3193 +Disproportionate short stature 15 29 2.832335572048436 0.0046209325408566 P42345,Q6DKJ4,Q32P28,Q03164,Q8WVQ1,Q9UHX1,Q15392,Q9UBM7,P16278,Q14739,Q96HY6,Q9BV10,Q7LGA3,Q8WTW3,O75718 Drugs and Diseases Human Phenotype Ontology msigdb_hp 530,516,132,68,332,135,70,141,263,175,640,115,637,245,394 1156,1031,2822,394,676,263,2937,807,530,1094,68,1736,1977,175,2376,1879,70,132,516,637,1369,245,332,1464,2528,640,115,141,135 0.26881271098746073,0.34579373996602075,-1.0274130001280428,0.8780699365084367,0.5889482912953588,1.0828619555333547,-1.2195274337089115,0.4940482237889104,0.7258739119100094,0.3203531886001632,2.1802255667070183,-0.0606293056858646,-0.20938691832830006,1.3659083845750073,-0.49595119132772597,-0.14899690656748693,2.1802255667070183,1.574489660490009,0.7480967979523666,0.6352911062035237,0.16298471623624555,1.1221876398575348,0.9822208710006587,0.10863077097339395,-0.631091924935383,0.6352911062035237,1.6735598720423626,1.5576536448951719,1.574489660490009 3193 +Golgi membrane 39 135 2.825883527398114 0.0047150405102029 Q9H7Z7,P10321,Q8IV08,Q12907,O60499,P53367,P24390,Q9P2W9,Q7Z3C6,Q9UL25,P42345,P62820,Q9Y282,O43505,Q9UBF8,O15498,Q9UM00,O60476,P50570,O43731,O95721,Q14108,O14617,Q12893,P04439,Q15392,O95197,Q9HC07,Q8IUD2,Q9Y296,O00461,O95295,Q13190,Q8NCH0,Q8TB61,P40616,Q8WTW3,Q7LGA3,Q8IZA0 Localization GO Cellular component msigdb_gocc 0,377,267,631,376,137,13,414,278,299,530,532,570,39,432,286,310,419,559,49,302,51,415,581,311,70,71,469,357,485,98,347,226,234,638,488,245,637,385 1715,98,2747,415,2158,1244,746,804,286,39,1765,49,1958,419,376,1299,2823,71,1386,347,302,3020,311,3033,2396,377,2695,1162,2318,13,920,1000,1868,488,530,1094,1262,961,2431,1495,559,1781,1869,1579,137,2368,1783,1043,2654,1397,1356,2625,1313,1784,965,1003,2328,532,1922,3026,757,1132,814,1875,855,581,631,226,687,51,1405,2892,2712,2019,1053,70,1455,789,1789,2786,1181,637,278,1460,935,357,267,385,1136,892,2091,234,2524,638,1982,661,245,1935,1699,1890,1278,1413,828,1187,2573,1467,2349,2035,1144,1802,2350,2301,0,1020,1192,469,2106,2219,1235,2691,414,1988,432,1340,2151,299,310,570,485,2903,3157,2820,745,1474,904 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3193 +Endothelial cell proliferation 6 18 2.817855565569652 0.004834555216796 P09601,P26583,Q8WTV0,Q9H2J4,Q12959,P57105 Processes and pathways GO Biological process msigdb_gobp 7,107,18,248,121,317 1030,1563,1670,2853,312,7,1771,2779,107,1040,1493,317,2437,121,18,1649,248,984 0.34579373996602075,0.025199324650836994,-0.031744908526115174,-1.065237448909853,1.0026222188239642,4.132037847844936,-0.08979570423491805,-0.9526617479367557,1.7536794627358119,0.34579373996602075,0.08107837999042887,1.0026222188239642,-0.5629231723307153,1.6409002994968682,3.4188452578218076,-0.0031371136066703498,1.1221876398575348,0.39603391908014063 3193 +Cellular response to chemical stress 9 72 2.8111082560403924 0.0049371171332852 P30519,P09601,P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 6,7,8,105,20,119,55,30,95 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3193 +Regulation of ph 8 22 2.807694095894135 0.0049897600304191 Q9Y6M7,P50897,O95295,Q8N511,Q9HC07,Q92544,Q9Y487,O75503 Processes and pathways GO Biological process msigdb_gobp 102,37,347,139,469,407,153,184 184,347,1962,2396,2234,1168,37,1629,1869,2554,1785,460,139,407,793,1371,469,1340,1710,153,987,102 1.3296832447901088,0.9409952878769652,-0.20938691832830006,-0.5292875863064875,-0.3977371338220593,0.26881271098746073,2.8414299150165303,-0.0031371136066703498,-0.14899690656748693,-0.6656250951850902,-0.08979570423491805,0.813790292416791,1.5576536448951719,0.8780699365084367,0.5180573956646057,0.16298471623624555,0.813790292416791,0.18979526604543842,-0.031744908526115174,1.5065684931882488,0.39603391908014063,1.8007392900685555 3193 +Regulation of cellular ph 8 22 2.807694095894135 0.0049897600304191 Q9Y6M7,P50897,O95295,Q8N511,Q9HC07,Q92544,Q9Y487,O75503 Processes and pathways GO Biological process msigdb_gobp 102,37,347,139,469,407,153,184 184,347,1962,2396,2234,1168,37,1629,1869,2554,1785,460,139,407,793,1371,469,1340,1710,153,987,102 1.3296832447901088,0.9409952878769652,-0.20938691832830006,-0.5292875863064875,-0.3977371338220593,0.26881271098746073,2.8414299150165303,-0.0031371136066703498,-0.14899690656748693,-0.6656250951850902,-0.08979570423491805,0.813790292416791,1.5576536448951719,0.8780699365084367,0.5180573956646057,0.16298471623624555,0.813790292416791,0.18979526604543842,-0.031744908526115174,1.5065684931882488,0.39603391908014063,1.8007392900685555 3193 +Switching of origins to a post replicative state 23 60 2.8025386931835765 0.0050702134014057 Q13416,P49721,Q99436,Q9UBD5,P28072,O00231,P60900,Q14566,Q14997,P24941,O43242,Q99741,P28070,Q06323,Q9Y619,P61289,P20618,P51665,P33991,P28074,Q16763,P25787,Q9H1A4 Processes and pathways Reactome Pathways msigdb_reactome 632,8,795,800,20,525,30,293,167,422,417,697,55,729,72,478,95,352,719,105,368,119,522 525,2356,1907,2050,1993,417,906,913,1916,95,422,781,2467,119,2162,2468,2400,55,20,105,1865,719,1627,1038,2996,2998,1261,1446,8,1494,352,3068,30,478,1631,2434,2802,1266,729,1008,1545,1639,632,1584,293,167,929,368,795,2143,697,522,800,2109,1807,1522,2537,1523,1295,72 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3193 +Alcohol biosynthetic process 9 37 2.7966493900479388 0.005163553340362 P35270,P48449,Q15392,Q9UBM7,P00374,Q13510,Q16850,P42765,P04062 Processes and pathways GO Biological process msigdb_gobp 131,99,70,141,14,50,93,61,158 2612,1668,1381,1564,2729,14,3092,507,158,2543,1087,2397,2507,2063,997,2119,131,1573,61,99,1782,2511,655,2516,50,1641,175,1879,1834,70,1880,381,3131,93,2946,1606,141 -0.7355890326334656,-0.031744908526115174,0.13593136335059053,0.025199324650836994,-0.8791073450641793,3.902465612713916,-1.7972452332773272,0.7480967979523666,1.4545942332074184,-0.6656250951850902,0.3203531886001632,-0.5292875863064875,-0.631091924935383,-0.2709736160130218,0.3710194511388473,-0.30221572716540523,1.574489660490009,0.025199324650836994,2.2345531829313767,1.8317054739763257,-0.08979570423491805,-0.631091924935383,0.612209574085093,-0.631091924935383,2.4045866103244666,-0.0031371136066703498,1.3659083845750073,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,-0.14899690656748693,0.8991926986389834,-2.062793041012379,1.9077445032407137,-1.2195274337089115,0.025199324650836994,1.5576536448951719 3193 +Abnormality of corneal stroma 6 13 2.778496126676293 0.0054611164369153 O43505,P16278,Q13510,P04062,P10619,P34913 Drugs and Diseases Human Phenotype Ontology msigdb_hp 39,263,50,158,60,190 39,1564,158,60,263,2677,360,1772,190,1682,50,759,2391 2.7180994529009332,0.025199324650836994,1.4545942332074184,2.261350745716217,1.0828619555333547,-0.8067497779060742,0.9201671263885668,-0.08979570423491805,1.2930133010682965,-0.031744908526115174,2.4045866103244666,0.5418751241716249,-0.49595119132772597 3193 +Lipid binding 28 134 2.777390449963618 0.0054797308721781 P09455,P53367,A6NIH7,Q8WTV0,Q9BQE5,P21796,O60749,P04062,Q13432,P53365,P50897,P45880,Q14849,Q14108,O15294,O60443,P28070,Q9NZJ7,Q8NCC3,P09429,P07602,P35610,O14964,O15118,P30536,P30086,Q15036,O95218 Functions GO Molecular function msigdb_gomf 128,137,15,18,27,26,274,158,31,164,37,38,294,51,174,54,55,321,64,312,67,324,322,208,100,351,367,235 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3193 +Ub specific processing proteases 22 78 2.776491194526522 0.0054949123456995 P49721,Q13546,P28072,Q96FW1,P21796,P60900,P45880,Q14997,Q9Y4E8,O43242,Q96RU2,P28070,P40818,Q15388,O14964,Q12834,P20618,P61289,P51665,P28074,P25787,Q9Y277 Processes and pathways Reactome Pathways msigdb_reactome 8,265,20,150,26,30,38,167,173,417,446,55,314,205,322,457,95,478,352,105,119,260 525,2356,1907,2050,1993,322,417,774,913,2728,1485,2773,1391,1916,95,26,2467,119,2162,2468,2400,55,20,105,2996,314,2998,38,2620,1261,2431,1446,8,352,2280,2653,3068,30,478,1631,2434,2802,729,457,1545,1639,265,2864,493,2806,167,929,205,3037,2082,1591,2563,2185,1279,1892,2032,150,662,446,795,2143,1377,2769,1753,1523,1295,1989,3112,260,1475,1618,173,1760 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3193 +Synthesis of dna 35 87 2.776109202157089 0.0055013727243169 Q13416,P49721,Q99436,Q9UBD5,P28072,P35244,O00231,P09884,P60900,Q14566,Q14997,P24941,Q99741,O43242,O75419,P28070,P35251,Q9NRF9,Q06323,Q9Y619,Q15054,Q9NR33,P18858,P20618,P49642,P51665,P61289,P33991,Q07864,P28074,Q16763,P25787,P41440,Q9Y2S7,Q9H1A4 Processes and pathways Reactome Pathways msigdb_reactome 632,8,795,800,20,397,525,777,30,293,167,422,697,417,301,55,555,588,729,72,459,221,716,95,598,352,478,719,225,105,368,119,243,648,522 525,2356,1907,2050,1993,417,906,301,913,777,2828,1163,1916,716,95,422,781,2467,119,2162,2468,1676,2400,55,20,105,1258,1865,719,1627,1038,397,2958,2698,555,2996,2322,1678,2236,243,2998,1261,2702,598,1311,1446,8,1494,352,3068,30,478,1631,2434,2802,1266,729,225,1008,1545,1639,632,1584,293,971,167,929,459,368,795,2143,697,861,1287,522,221,588,800,2109,1807,1522,2537,1523,1295,1028,648,72 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.0228851550061475,0.42084065117869884,0.5180573956646057,-1.0274130001280428,0.26881271098746073,-0.1790423277350827,0.5655044371788908,1.8775608468012885,0.856796727704752,0.5180573956646057,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.031744908526115174,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.21636733085825482,-0.14899690656748693,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,-1.258847985434175,-0.8427789578797747,0.7034844439548688,-1.3786049993712943,-0.462913985518726,-0.031744908526115174,-0.3977371338220593,1.1221876398575348,-1.3786049993712943,0.21636733085825482,-0.8427789578797747,0.6581956434453833,0.18979526604543842,0.10863077097339395,4.132037847844936,0.08107837999042887,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,1.1802219848882647,0.3710194511388473,0.053269504024264246,-0.0031371136066703498,0.6352911062035237,0.025199324650836994,1.0430115443451933,0.39603391908014063,1.41943529737493,0.42084065117869884,0.813790292416791,0.9201671263885668,0.5180573956646057,-0.30221572716540523,0.5889482912953588,0.4698445071041799,0.21636733085825482,0.7480967979523666,1.1993188415722877,0.680925878721421,0.5180573956646057,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.21636733085825482,0.3710194511388473,0.6352911062035237,2.166487793701175 3193 +Cation transmembrane transporter activity 14 67 2.766951539347388 0.0056583165540773 P13073,Q7KZN9,Q9Y6M7,Q9Y619,Q96ES6,Q9H936,O95202,Q9HC21,O75964,Q9Y487,Q8TAD4,O43772,Q70HW3,Q9UDW1 Functions GO Molecular function msigdb_gomf 253,192,102,72,12,78,262,112,81,153,280,23,88,59 23,874,2613,81,262,959,2991,2644,1161,1962,1864,2969,2061,651,2115,527,253,1821,2647,1166,3009,2649,554,2779,1866,1723,1208,2959,1093,2701,1869,1211,1827,1355,2554,2074,3026,1733,1687,458,1504,1835,1589,88,192,2599,280,1113,793,12,1372,664,698,2768,1852,78,1234,469,112,483,1290,59,1710,310,153,72,102 3.222435477932678,0.44544306819693447,-0.7355890326334656,2.025517574520846,1.0828619555333547,0.39603391908014063,-1.3786049993712943,-0.7710198034073763,0.26881271098746073,-0.20938691832830006,-0.14899690656748693,-1.2984677625692256,-0.2709736160130218,0.612209574085093,-0.30221572716540523,0.7258739119100094,1.102589523776575,-0.11924966294507812,-0.7710198034073763,0.26881271098746073,-1.419122462160247,-0.7710198034073763,0.7034844439548688,-0.9526617479367557,-0.14899690656748693,-0.0606293056858646,0.2427051145911597,-1.258847985434175,0.3203531886001632,-0.8427789578797747,-0.14899690656748693,0.2427051145911597,-0.11924966294507812,0.16298471623624555,-0.6656250951850902,-0.2709736160130218,-1.459939156603208,-0.0606293056858646,-0.031744908526115174,0.813790292416791,0.08107837999042887,-0.11924966294507812,0.025199324650836994,1.9524555180193348,1.2930133010682965,-0.7004574638193659,1.063003214209736,0.3203531886001632,0.5180573956646057,3.985962658179109,0.16298471623624555,0.612209574085093,0.5889482912953588,-0.9157349411807121,-0.11924966294507812,2.068511822464931,0.2427051145911597,0.813790292416791,1.7058661157411827,0.7920526088666452,0.21636733085825482,2.2746598733113577,-0.031744908526115174,1.0228851550061475,1.5065684931882488,2.166487793701175,1.8007392900685555 3193 +secondary carrier transporter 8 14 2.764990241375564 0.0056924498727255 Q9Y6M7,Q96ES6,Q9H936,Q8TB61,O95202,Q9BQT8,Q9UBX3,Q02978 Functions Panther Protein class panther_protein_class 102,12,78,638,262,56,259,479 1160,262,1211,479,1504,1643,638,12,56,698,78,259,1025,102 0.26881271098746073,1.0828619555333547,0.2427051145911597,0.7920526088666452,0.08107837999042887,-0.0031371136066703498,0.6352911062035237,3.985962658179109,2.301101464563815,0.5889482912953588,2.068511822464931,1.102589523776575,0.3710194511388473,1.8007392900685555 3193 +Outer membrane 30 93 2.741395743338182 0.006117877256154 P09601,Q9UBM7,Q8N4H5,Q5VT66,Q9NS69,P21796,Q13057,Q9NVT9,P45880,Q13505,Q9UBF8,Q16611,O43169,Q9NQ88,Q9Y6C9,Q9NZJ7,Q99720,P57105,Q9NZ45,Q6UXV4,Q15388,Q9BWH2,P30536,Q8IWA4,Q96RL7,Q9GZY8,P50402,Q8N0X7,Q8N2A8,Q9Y277 Localization GO Cellular component msigdb_gocc 7,141,142,402,24,26,156,163,38,166,432,171,45,178,182,321,57,317,333,203,205,482,100,233,497,247,490,519,386,260 1619,1526,505,2051,45,748,2727,2674,2541,2728,2730,2587,1388,3092,2774,2363,7,3129,26,100,3108,3118,530,1628,38,490,2324,2882,1174,317,2169,156,166,2079,1324,205,1788,171,1881,2628,402,1838,611,2132,203,2760,233,2915,2563,519,386,142,2719,3039,2092,2295,1331,1648,2032,2095,2253,497,2098,663,1414,57,2870,1467,3059,482,247,2577,667,178,1608,1021,24,1609,1520,1023,163,1339,1291,1235,333,321,432,141,1855,260,2820,1476,182 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3193 +Peptide binding 17 70 2.6825539971564942 0.0073062355930619 Q9H7Z7,P04439,P10321,Q9NZ08,Q15392,P55786,Q92973,P24390,Q15388,Q9UIQ6,O00505,O43731,Q8WTV0,P42892,Q03518,Q9NQX7,Q6UX04 Functions GO Molecular function msigdb_gomf 0,311,377,272,70,101,370,13,205,47,261,49,18,120,87,220,189 591,1526,1242,261,622,1666,2694,49,712,2728,3020,311,750,1769,377,1391,2366,2937,13,2547,2957,2275,2401,2402,1726,120,2238,2430,2432,2279,1579,510,2999,101,2197,2074,2555,2370,87,756,3105,2127,1402,2594,2128,2836,2784,205,70,1740,189,2839,937,18,370,1846,410,521,3073,1374,1418,0,220,2043,272,1613,705,47,2420,2268 0.6581956434453833,0.053269504024264246,0.21636733085825482,1.0828619555333547,0.6352911062035237,-0.031744908526115174,-0.8427789578797747,2.4299070151136095,0.5655044371788908,-0.8791073450641793,-1.459939156603208,1.0026222188239642,0.5418751241716249,-0.08979570423491805,0.8991926986389834,0.13593136335059053,-0.49595119132772597,-1.2195274337089115,3.9784678086896657,-0.6656250951850902,-1.258847985434175,-0.4301759669868179,-0.5292875863064875,-0.5292875863064875,-0.0606293056858646,1.6409002994968682,-0.3977371338220593,-0.5629231723307153,-0.5629231723307153,-0.4301759669868179,0.025199324650836994,0.7480967979523666,-1.3786049993712943,1.8007392900685555,-0.3655974840969154,-0.2709736160130218,-0.6656250951850902,-0.49595119132772597,1.9818952092384208,0.5418751241716249,-1.8407550802597537,-0.30221572716540523,0.13593136335059053,-0.7004574638193659,-0.30221572716540523,-1.0274130001280428,-0.9526617479367557,1.2371500809699392,2.1802255667070183,-0.0606293056858646,1.3114045548408733,-1.0274130001280428,0.42084065117869884,3.4188452578218076,0.9201671263885668,-0.11924966294507812,0.8780699365084367,0.7480967979523666,-1.6685111568748416,0.16298471623624555,0.13593136335059053,5.424822935915991,1.1993188415722877,-0.24003068040751657,1.0828619555333547,0.025199324650836994,0.5889482912953588,2.5046047789471104,-0.5292875863064875,-0.3977371338220593 3193 +Intrinsic component of mitochondrial inner membrane 7 30 2.6649553860241117 0.007699853706665 Q99595,Q13505,Q6UXV4,O14925,Q9HC21,O60830,Q9Y2R0 Localization GO Cellular component msigdb_gocc 32,166,203,169,112,17,116 169,1766,17,2541,2360,200,3118,2981,1733,166,326,819,1881,2628,1838,2026,203,2599,1372,32,1467,1114,1234,2667,112,1023,1291,116,1905,1476 1.383857498630824,-0.08979570423491805,3.6453743945093926,-0.6656250951850902,-0.49595119132772597,1.2558874980500507,-1.9730801058799055,-1.3383867666926692,-0.0606293056858646,1.41943529737493,0.9822208710006587,0.4940482237889104,-0.14899690656748693,-0.7355890326334656,-0.11924966294507812,-0.24003068040751657,1.2558874980500507,-0.7004574638193659,0.16298471623624555,2.9598669449402526,0.10863077097339395,0.3203531886001632,0.2427051145911597,-0.7710198034073763,1.7058661157411827,0.3710194511388473,0.21636733085825482,1.6735598720423626,-0.14899690656748693,0.10863077097339395 3193 +Circulatory system process 15 73 2.652663124214065 0.0079859529491885 P78417,O75844,P41440,Q9NZ08,P09601,P14923,P42785,Q9UIQ6,P53985,Q9HB40,P08183,P15924,Q12959,P42892,O76003 Processes and pathways GO Biological process msigdb_gobp 1,129,243,272,7,290,9,47,82,22,147,86,121,120,187 505,1122,1763,2113,2795,2641,129,187,625,3092,749,2825,3122,2991,2644,2731,147,7,303,2695,1489,2777,290,86,1821,2647,2545,2508,1259,243,1493,530,9,120,922,578,851,1129,2780,2196,82,1211,1356,1045,2015,1,2974,811,2860,1176,1451,121,687,2656,427,1975,1324,1835,759,1643,1792,2898,1463,664,465,22,2847,1518,272,470,1557,47,872 0.7480967979523666,0.29469410743066005,-0.08979570423491805,-0.30221572716540523,-0.9898877670258749,-0.7710198034073763,1.5912312904288737,1.3114045548408733,0.6352911062035237,-1.7972452332773272,0.5418751241716249,-1.0274130001280428,-2.0177869473716163,-1.3786049993712943,-0.7710198034073763,-0.8791073450641793,1.5065684931882488,4.132037847844936,1.0228851550061475,-0.8427789578797747,0.08107837999042887,-0.9526617479367557,1.0430115443451933,1.9818952092384208,-0.11924966294507812,-0.7710198034073763,-0.6656250951850902,-0.631091924935383,0.21636733085825482,1.1221876398575348,0.08107837999042887,0.7258739119100094,4.117747886511145,1.6409002994968682,0.42084065117869884,0.680925878721421,0.4698445071041799,0.29469410743066005,-0.9526617479367557,-0.3655974840969154,2.025517574520846,0.2427051145911597,0.16298471623624555,0.34579373996602075,-0.24003068040751657,5.401623940688195,-1.2984677625692256,0.4940482237889104,-1.065237448909853,0.26881271098746073,0.10863077097339395,1.6409002994968682,0.5889482912953588,-0.7710198034073763,0.856796727704752,-0.20938691832830006,0.18979526604543842,-0.11924966294507812,0.5418751241716249,-0.0031371136066703498,-0.08979570423491805,-1.103361115024735,0.10863077097339395,0.612209574085093,0.813790292416791,3.24170793389333,-1.0274130001280428,0.08107837999042887,1.0828619555333547,0.813790292416791,0.053269504024264246,2.5046047789471104,0.4698445071041799 3193 +Peptidase complex 17 62 2.623179816174218 0.0087113282356336 P51665,O43396,P67812,Q14997,P49721,Q5VYK3,P61289,P28074,Q8IWV7,O43242,P28072,Q9Y6J9,P25787,P28070,P04792,P60900,P20618 Localization GO Cellular component msigdb_gocc 352,196,292,167,8,382,478,105,495,417,20,183,119,55,185,30,95 525,2356,1907,2050,1993,417,196,1909,913,185,2004,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,1041,352,2653,1042,3068,2982,30,1097,478,1631,2434,2802,292,1785,729,1545,167,1738,929,1407,2082,382,495,1061,1984,2529,795,2143,2900,863,1523,1295,1618,1905,2821,183 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,1.2745080889897082,-0.1790423277350827,0.42084065117869884,1.3296832447901088,-0.24003068040751657,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.34579373996602075,0.9409952878769652,-0.7710198034073763,0.34579373996602075,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.3203531886001632,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.0430115443451933,-0.08979570423491805,0.5655044371788908,0.053269504024264246,1.41943529737493,-0.0606293056858646,0.42084065117869884,0.13593136335059053,-0.2709736160130218,0.8991926986389834,0.7701555617414707,0.34579373996602075,-0.20938691832830006,-0.631091924935383,0.5180573956646057,-0.30221572716540523,-1.103361115024735,0.4698445071041799,0.08107837999042887,0.21636733085825482,0.025199324650836994,-0.14899690656748693,-0.9898877670258749,1.3478507399601813 3193 +Glycosyltransferase activity 9 43 2.61520356714372 0.0089174289917373 P43490,Q9H488,O43505,Q2TAA5,Q16880,Q9BV10,O15294,Q9BT22,P04062 Functions GO Molecular function msigdb_gomf 96,230,39,108,188,115,174,91,158 2421,174,39,2113,2056,1563,1347,1534,158,1819,1440,1085,1389,2645,1487,1390,2776,1568,2317,1776,96,254,1171,2242,2372,814,379,188,108,658,1840,1459,2789,2600,1413,91,115,230,2577,947,1423,1077,2157 -0.5629231723307153,1.3659083845750073,2.7180994529009332,-0.30221572716540523,-0.2709736160130218,0.025199324650836994,0.16298471623624555,0.053269504024264246,1.4545942332074184,-0.11924966294507812,0.10863077097339395,0.3203531886001632,0.13593136335059053,-0.7710198034073763,0.08107837999042887,0.13593136335059053,-0.9526617479367557,0.025199324650836994,-0.462913985518726,-0.08979570423491805,1.8775608468012885,1.102589523776575,0.26881271098746073,-0.3977371338220593,-0.49595119132772597,0.4940482237889104,0.8991926986389834,1.3114045548408733,1.7536794627358119,0.612209574085093,-0.11924966294507812,0.10863077097339395,-0.9526617479367557,-0.7004574638193659,0.13593136335059053,1.9227226839549494,1.6735598720423626,1.1802219848882647,-0.6656250951850902,0.42084065117869884,0.13593136335059053,0.34579373996602075,-0.30221572716540523 3193 +Ion transport 39 200 2.594785995425854 0.0094649831673625 P13073,P78417,O75844,Q96ES6,Q13546,O95202,Q8TAD4,O43772,P08183,P62942,P21796,P42858,Q9H2D1,P45880,P51798,Q16611,Q9UM00,Q7L0J3,Q9BQT8,Q9NZJ7,Q9UDW1,Q7KZN9,P07602,Q9Y619,O00299,Q9H936,O75964,P53985,Q70HW3,Q9C0H2,Q9Y6M7,P30536,P41440,Q9UBX3,Q9HC21,P14174,Q12959,Q9UHG3,Q9Y277 Processes and pathways GO Biological process msigdb_gobp 253,1,129,12,265,262,280,23,147,148,26,155,35,38,291,171,310,53,56,321,59,192,67,72,198,78,81,82,88,94,102,100,243,259,112,242,121,123,260 2463,198,505,1762,1763,572,2270,435,624,1247,23,874,1159,1716,346,673,2673,1344,2674,3084,1160,129,1084,2613,81,1767,262,1817,1388,959,749,1567,3122,2991,2644,1720,1161,1441,2114,1962,1864,2231,67,2969,147,2061,651,2396,2115,2695,2676,1087,527,751,253,1088,242,1821,2063,1771,2647,1166,3009,2649,2545,26,554,422,2779,577,3034,752,2957,100,2508,1866,1572,1259,720,1723,1208,2959,243,155,38,2922,1394,1395,1093,2701,559,1869,291,1497,1630,82,1681,2369,1211,1827,1355,580,2554,2074,1045,148,1,2974,3026,1733,1687,1635,1830,479,1874,1359,3105,2706,1688,2438,121,458,265,1692,2656,1268,1102,1177,2865,818,1504,2712,1835,1054,171,1325,328,2290,1643,2026,1589,88,192,53,2810,1105,2898,2961,1796,2599,280,638,824,587,1113,12,2411,2605,1372,1187,2946,1414,664,465,1894,56,2575,3059,698,94,2576,2768,1190,35,1852,78,1234,469,112,483,2106,2847,1290,321,259,59,1340,123,1710,1025,1558,310,1757,1237,260,2355,1905,72,987,102 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3193 +Regulation of endothelial cell migration 7 27 2.591775129460498 0.0095482159909727 P09429,P14923,P09601,P42785,Q8WTV0,P04792,P57105 Processes and pathways GO Biological process msigdb_gobp 312,290,7,9,18,185,317 1122,1030,2795,1563,625,1567,185,1962,1348,312,7,290,1771,2779,2547,9,922,2780,317,1500,340,3027,635,18,942,2148,1947 0.29469410743066005,0.34579373996602075,-0.9898877670258749,0.025199324650836994,0.6352911062035237,0.025199324650836994,1.3296832447901088,-0.20938691832830006,0.16298471623624555,1.0026222188239642,4.132037847844936,1.0430115443451933,-0.08979570423491805,-0.9526617479367557,-0.6656250951850902,4.117747886511145,0.42084065117869884,-0.9526617479367557,1.0026222188239642,0.08107837999042887,0.9616792082789943,-1.459939156603208,0.6352911062035237,3.4188452578218076,0.42084065117869884,-0.30221572716540523,-0.1790423277350827 3193 +Alcohol binding 7 15 2.58658291055255 0.0096932846985682 P09455,Q14849,P30536,P45880,Q14108,O15118,P21796 Functions GO Molecular function msigdb_gomf 128,294,100,38,51,208,26 208,2056,2729,2969,128,26,2065,100,324,38,1131,51,294,1232,2767 1.2182943630695027,-0.2709736160130218,-0.8791073450641793,-1.2984677625692256,1.6078795867372875,3.0940370861233606,-0.2709736160130218,1.8007392900685555,0.9822208710006587,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121 3193 +Class i mhc mediated antigen processing presentation 28 113 2.586284273381877 0.009701687949664 P10321,Q9NZ08,P49721,P28072,Q9UBS8,P60900,Q14997,P19474,Q9UIQ6,O43242,P28070,P09429,P04439,Q12834,P61088,Q03518,O95487,P20618,P61289,P51665,P49427,P55786,P28074,Q7Z7E8,Q16763,Q8IWV7,P25787,Q9H1A4 Processes and pathways Reactome Pathways msigdb_reactome 377,272,8,20,21,30,167,43,47,417,55,312,311,457,455,87,213,95,478,352,477,101,105,237,368,495,119,522 1952,2463,525,2356,1907,2050,1993,989,417,2823,913,626,1532,1301,2642,995,213,3020,311,312,377,1916,43,95,2735,2467,119,2162,2468,2547,2399,2400,55,20,105,2235,2697,1865,2996,2998,1394,1261,477,1446,8,1781,352,2325,1870,3068,2476,101,2859,30,1212,754,455,478,2074,1631,2434,2802,1266,1213,87,1785,729,457,2707,1008,1545,1639,1584,603,1048,928,2243,167,929,1693,2627,3099,1407,1455,368,3038,932,761,1460,237,495,1889,792,1113,2298,795,2143,1067,522,799,272,21,47,2109,1807,1522,2537,1523,1076,3089,1295,902,1760 -0.20938691832830006,-0.5968579512594566,0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,-1.0274130001280428,0.42084065117869884,0.6352911062035237,0.053269504024264246,0.18979526604543842,-0.7710198034073763,0.3710194511388473,1.1993188415722877,-1.459939156603208,1.0026222188239642,1.0026222188239642,0.8991926986389834,-0.1790423277350827,2.6013806888194835,1.8775608468012885,-0.8791073450641793,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.6656250951850902,-0.5292875863064875,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.3977371338220593,-0.8427789578797747,-0.14899690656748693,-1.3786049993712943,-1.3786049993712943,0.13593136335059053,0.21636733085825482,0.7920526088666452,0.10863077097339395,4.132037847844936,-0.08979570423491805,0.9409952878769652,-0.462913985518726,-0.14899690656748693,-1.6685111568748416,-0.5968579512594566,1.8007392900685555,-1.065237448909853,3.0017959971834336,0.2427051145911597,0.5418751241716249,0.813790292416791,0.7920526088666452,-0.2709736160130218,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.2427051145911597,1.9818952092384208,-0.08979570423491805,0.5655044371788908,0.813790292416791,-0.8427789578797747,0.3710194511388473,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.6581956434453833,0.34579373996602075,0.42084065117869884,-0.3977371338220593,1.41943529737493,0.42084065117869884,-0.031744908526115174,-0.7355890326334656,-1.7972452332773272,0.13593136335059053,0.10863077097339395,0.9201671263885668,-1.5010550842325505,0.42084065117869884,0.5418751241716249,0.10863077097339395,1.1416579910536835,0.7701555617414707,-0.14899690656748693,0.5180573956646057,0.3203531886001632,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.34579373996602075,0.7480967979523666,0.5180573956646057,1.0828619555333547,3.2893516380101935,2.5046047789471104,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.34579373996602075,-1.7540346313524435,0.21636733085825482,0.44544306819693447,-0.0606293056858646 3193 +Cyclin a cdk2 associated events at s phase entry 14 43 2.582247250352172 0.0098159232734933 P51665,P49721,P28074,P61289,P24941,O43242,P28072,P25787,P28070,P11802,O00231,P06400,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 352,8,105,478,422,417,20,119,55,215,525,277,30,95 525,2356,1907,2050,1993,417,913,277,215,1916,95,422,2467,119,2162,2468,2400,55,20,105,529,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.063003214209736,1.1993188415722877,-0.1790423277350827,1.8775608468012885,0.856796727704752,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.7258739119100094,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Cholesterol metabolism with bloch and kandutschrussell pathways 9 25 2.577353044776112 0.0099560205677007 Q15800,P48449,Q9BWD1,O00767,Q15392,Q9UBM7,P35610,Q14739,Q16850 Processes and pathways WikiPathways msigdb_wp 381,99,4,506,70,141,324,175,93 506,2727,1564,2587,1253,507,2397,3108,324,1573,99,1577,2511,2516,1641,1320,175,1879,1834,70,1880,381,93,4,141 0.7480967979523666,-0.8791073450641793,0.025199324650836994,-0.7004574638193659,0.21636733085825482,0.7480967979523666,-0.5292875863064875,-1.8845641737373735,0.9822208710006587,0.025199324650836994,1.8317054739763257,0.025199324650836994,-0.631091924935383,-0.631091924935383,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,-0.14899690656748693,0.8991926986389834,1.9077445032407137,4.665813426727727,1.5576536448951719 3193 +Synaptic vesicle transport 8 12 2.575082977613665 0.0100216041197862 O00203,O95295,Q9Y2T2,P50570,O14617,P78537,O43426,Q96A57 Processes and pathways GO Biological process msigdb_gobp 472,347,503,559,415,680,650,319 472,415,650,347,1572,720,559,680,1687,2128,319,503 0.7920526088666452,0.856796727704752,0.612209574085093,0.9409952878769652,0.025199324650836994,0.5655044371788908,0.7034844439548688,0.5889482912953588,-0.031744908526115174,-0.30221572716540523,1.0026222188239642,0.7701555617414707 3193 +Metapathway biotransformation phase i and ii 8 20 2.5663619768533 0.0102771517136937 P78417,P07099,Q8NCH0,Q9GZZ1,Q86UY6,Q6UW02,Q16850,P34913 Processes and pathways WikiPathways msigdb_wp 1,5,234,371,206,442,93,190 1623,3008,2500,5,2003,2116,2366,1774,190,2430,1,93,442,637,206,234,521,371,2260,2307 -0.0031371136066703498,-1.419122462160247,-0.631091924935383,4.653868521654828,-0.24003068040751657,-0.30221572716540523,-0.49595119132772597,-0.08979570423491805,1.2930133010682965,-0.5629231723307153,5.401623940688195,1.9077445032407137,0.8353709145003145,0.6352911062035237,1.2371500809699392,1.1610022318711952,0.7480967979523666,0.9201671263885668,-0.3977371338220593,-0.4301759669868179 3193 +Dna replication 38 94 2.5597258565657004 0.0104754762149719 Q13416,P49721,P52294,Q99436,Q9UBD5,P28072,P35244,O00231,P09884,P60900,Q14566,Q14997,P24941,Q99741,O43242,O75419,P28070,P35251,Q9NRF9,Q06323,Q9Y619,Q15054,Q9NR33,P18858,Q7L590,O60684,P20618,P49642,P51665,P61289,P33991,Q07864,P28074,Q16763,P25787,P41440,Q9Y2S7,Q9H1A4 Processes and pathways Reactome Pathways msigdb_reactome 632,8,510,795,800,20,397,525,777,30,293,167,422,697,417,301,55,555,588,729,72,459,221,716,216,712,95,598,352,478,719,225,105,368,119,243,648,522 525,2356,1907,2050,1993,417,906,712,301,913,777,2828,1163,3067,1916,716,95,422,781,2467,119,2162,2468,1676,2400,55,20,105,1258,1865,719,1627,1038,397,2958,2698,555,2996,2322,1678,2236,243,2998,1261,2702,598,1311,1446,8,1494,352,510,3068,30,478,1631,2434,2802,2803,1266,1685,729,225,1008,1545,1639,632,1584,293,971,2836,167,929,459,368,216,795,2143,697,861,1287,522,221,588,800,2109,1807,1522,2537,1523,1295,1028,648,72 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.5655044371788908,1.0228851550061475,0.42084065117869884,0.5180573956646057,-1.0274130001280428,0.26881271098746073,-1.6685111568748416,-0.1790423277350827,0.5655044371788908,1.8775608468012885,0.856796727704752,0.5180573956646057,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.031744908526115174,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.21636733085825482,-0.14899690656748693,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,-1.258847985434175,-0.8427789578797747,0.7034844439548688,-1.3786049993712943,-0.462913985518726,-0.031744908526115174,-0.3977371338220593,1.1221876398575348,-1.3786049993712943,0.21636733085825482,-0.8427789578797747,0.6581956434453833,0.18979526604543842,0.10863077097339395,4.132037847844936,0.08107837999042887,0.9409952878769652,0.7480967979523666,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.9898877670258749,0.21636733085825482,-0.031744908526115174,0.5655044371788908,1.1802219848882647,0.3710194511388473,0.053269504024264246,-0.0031371136066703498,0.6352911062035237,0.025199324650836994,1.0430115443451933,0.39603391908014063,-1.0274130001280428,1.41943529737493,0.42084065117869884,0.813790292416791,0.9201671263885668,1.1993188415722877,0.5180573956646057,-0.30221572716540523,0.5889482912953588,0.4698445071041799,0.21636733085825482,0.7480967979523666,1.1993188415722877,0.680925878721421,0.5180573956646057,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.21636733085825482,0.3710194511388473,0.6352911062035237,2.166487793701175 3193 +Abnormal pulmonary interstitial morphology 12 30 2.5577468892734645 0.0105352743251168 Q8IZA0,O00203,P09601,Q9UJW0,O14617,Q13510,Q14108,P15924,P14174,Q9Y285,P04062,Q13432 Drugs and Diseases Human Phenotype Ontology msigdb_hp 385,472,7,240,415,50,51,86,242,590,158,31 472,415,2160,2312,158,7,242,86,2063,2366,1040,578,1577,1783,2704,2552,2124,2435,31,50,51,1324,2895,2179,385,2841,2264,3082,240,590 0.7920526088666452,0.856796727704752,-0.3337570158659335,-0.462913985518726,1.4545942332074184,4.132037847844936,1.1221876398575348,1.9818952092384208,-0.2709736160130218,-0.49595119132772597,0.34579373996602075,0.680925878721421,0.025199324650836994,-0.08979570423491805,-0.8427789578797747,-0.6656250951850902,-0.30221572716540523,-0.5629231723307153,2.9809050828258044,2.4045866103244666,2.391845426042903,0.18979526604543842,-1.103361115024735,-0.3337570158659335,0.8991926986389834,-1.0274130001280428,-0.3977371338220593,-1.7111232730375066,1.1416579910536835,0.680925878721421 3193 +Organophosphate ester transport 7 25 2.546538451555696 0.0108797224656038 Q9BSK2,Q9H2D1,Q9HC21,Q8WTV0,Q14108,P08183,P41440 Processes and pathways GO Biological process msigdb_gobp 255,35,112,18,51,147,243 874,1161,147,527,751,2318,2065,1259,243,1262,1131,2706,51,2290,278,638,824,18,2411,664,255,1232,35,112,2691 0.44544306819693447,0.26881271098746073,1.5065684931882488,0.7258739119100094,0.5418751241716249,-0.462913985518726,-0.2709736160130218,0.21636733085825482,1.1221876398575348,0.21636733085825482,0.29469410743066005,-0.8427789578797747,2.391845426042903,-0.4301759669868179,1.063003214209736,0.6352911062035237,0.4940482237889104,3.4188452578218076,-0.5292875863064875,0.612209574085093,1.102589523776575,0.2427051145911597,2.863316355216428,1.7058661157411827,-0.8067497779060742 3193 +Orc1 removal from chromatin 21 52 2.544353034388281 0.0109480371495354 Q13416,P49721,Q99436,Q9UBD5,P28072,O00231,P60900,Q14566,Q14997,P24941,O43242,Q99741,P28070,Q06323,Q9Y619,P61289,P20618,P51665,P33991,P28074,P25787 Processes and pathways Reactome Pathways msigdb_reactome 632,8,795,800,20,525,30,293,167,422,417,697,55,729,72,478,95,352,719,105,119 525,2356,1907,2050,1993,417,906,913,1916,95,422,781,2467,119,2162,2468,2400,55,20,105,719,1627,1038,2996,2998,1261,1446,8,1494,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,632,1584,293,167,929,795,2143,697,800,1523,1295,72 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.42084065117869884,-0.1790423277350827,1.8775608468012885,0.856796727704752,0.5180573956646057,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.08107837999042887,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.6352911062035237,0.025199324650836994,1.0430115443451933,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.5889482912953588,0.5180573956646057,0.08107837999042887,0.21636733085825482,2.166487793701175 3193 +golgi 19 63 2.5403771010331164 0.0110733003319396 Q9NR31,Q15437,P53367,Q9Y487,Q8TAD4,Q7Z3C6,P62820,P53365,Q9UBF8,Q9UM00,Q8IXU6,Q5VW38,Q15904,Q96A49,Q13190,Q969E2,P40616,Q7Z392,Q8IZA0 Localization OpenCell Localization opencell_localization 523,514,137,153,280,278,532,164,432,310,48,65,460,616,226,110,488,384,385 2747,2158,1763,1480,594,990,746,2359,1301,3019,1769,652,1570,2318,920,1208,488,1495,164,137,1783,1870,2550,2476,1313,1784,1003,532,1635,2126,226,970,1455,514,460,1054,65,384,278,48,385,892,2091,280,1935,1699,110,616,1802,768,1020,523,2219,2691,1988,432,1152,310,2820,1474,1121,153,904 -0.9157349411807121,-0.3337570158659335,-0.08979570423491805,0.08107837999042887,0.6581956434453833,0.3710194511388473,0.5418751241716249,-0.49595119132772597,0.18979526604543842,-1.459939156603208,-0.08979570423491805,0.612209574085093,0.025199324650836994,-0.462913985518726,0.42084065117869884,0.2427051145911597,0.7701555617414707,0.08107837999042887,1.41943529737493,1.5576536448951719,-0.08979570423491805,-0.14899690656748693,-0.6656250951850902,-0.5968579512594566,0.18979526604543842,-0.08979570423491805,0.3710194511388473,0.7258739119100094,-0.0031371136066703498,-0.30221572716540523,1.1802219848882647,0.39603391908014063,0.10863077097339395,0.7480967979523666,0.813790292416791,0.34579373996602075,2.193900422541388,0.8991926986389834,1.063003214209736,2.492284212516803,0.8991926986389834,0.44544306819693447,-0.2709736160130218,1.063003214209736,-0.1790423277350827,-0.031744908526115174,1.7378265912614526,0.6581956434453833,-0.08979570423491805,0.5418751241716249,0.3710194511388473,0.7480967979523666,-0.3655974840969154,-0.8067497779060742,-0.20938691832830006,0.856796727704752,0.29469410743066005,1.0228851550061475,-0.9898877670258749,0.10863077097339395,0.3203531886001632,1.5065684931882488,0.44544306819693447 3193 +Glycoprotein biosynthetic process 14 49 2.5343900028305755 0.0112643285696181 Q9H488,O14734,Q8WVQ1,O43505,Q8NCH0,P35610,Q2TAA5,O60476,Q9BV10,O15294,O60502,O15118,Q9NQX7,Q9BT22 Processes and pathways GO Biological process msigdb_gobp 230,251,332,39,234,324,108,419,115,174,300,208,220,91 2421,251,208,174,2639,39,419,300,2113,2056,1563,2311,1819,1440,720,324,2276,1171,1448,1922,2242,1971,814,2286,1318,789,108,658,637,1459,1224,234,2600,332,1461,1413,832,91,115,2768,230,2301,469,220,2494,947,1340,1759,2157 -0.5629231723307153,1.102589523776575,1.2182943630695027,1.3659083845750073,-0.7710198034073763,2.7180994529009332,0.856796727704752,1.0228851550061475,-0.30221572716540523,-0.2709736160130218,0.025199324650836994,-0.462913985518726,-0.11924966294507812,0.10863077097339395,0.5655044371788908,0.9822208710006587,-0.4301759669868179,0.26881271098746073,0.10863077097339395,-0.1790423277350827,-0.3977371338220593,-0.20938691832830006,0.4940482237889104,-0.4301759669868179,0.18979526604543842,0.5180573956646057,1.7536794627358119,0.612209574085093,0.6352911062035237,0.10863077097339395,0.2427051145911597,1.1610022318711952,-0.7004574638193659,0.9822208710006587,0.10863077097339395,0.13593136335059053,0.4940482237889104,1.9227226839549494,1.6735598720423626,-0.9157349411807121,1.1802219848882647,-0.4301759669868179,0.813790292416791,1.1993188415722877,-0.5968579512594566,0.42084065117869884,0.18979526604543842,-0.0606293056858646,-0.30221572716540523 3193 +Cdt1 association with the cdc6 orc origin complex 8 42 2.532430411895784 0.0113274851407036 P49721,Q9Y619,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,72,105,20,119,55,30,95 525,2356,1907,2050,1993,417,906,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,632,167,929,795,2143,697,800,1523,1295,72 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.6352911062035237,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.5889482912953588,0.5180573956646057,0.08107837999042887,0.21636733085825482,2.166487793701175 3193 +Hedgehog ligand biogenesis 8 40 2.5185830104067155 0.011782810581586 P49721,P28074,Q9UBV2,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,152,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1486,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,2982,30,478,1631,2434,2802,729,1545,167,929,795,2143,152,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.08107837999042887,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,1.5065684931882488,0.08107837999042887,0.21636733085825482 3193 +Deubiquitination 27 100 2.5137750847726927 0.0119446583660356 Q6P4R8,P49721,Q13546,Q8NB78,P28072,Q96FW1,P21796,P60900,P45880,Q14997,Q9Y4E8,O43242,O15294,Q96RU2,P28070,P40818,Q15388,O14964,Q12834,P20618,Q6GQQ9,P51665,P61289,P28074,P06493,P25787,Q9Y277 Processes and pathways Reactome Pathways msigdb_reactome 383,8,265,279,20,150,26,30,38,167,173,417,174,446,55,314,205,322,457,95,355,352,478,105,236,119,260 525,2356,1907,2050,1993,322,174,417,774,913,2728,1485,1719,2968,2773,236,1391,1916,95,26,1675,782,2467,119,2162,2468,2400,55,20,105,2996,1574,314,2998,38,2620,1261,2431,1446,8,2683,352,2280,2653,1042,3068,2982,30,478,1631,2434,2802,1314,729,457,1545,1639,265,1503,2864,493,2806,167,929,930,205,3037,2082,355,383,2760,1591,2563,279,2345,2185,1279,1892,2032,150,662,446,795,2143,738,1377,2769,3017,2043,1753,1523,1295,1989,3112,260,1475,1618,173,2821,1760 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.9822208710006587,1.3659083845750073,0.856796727704752,0.5180573956646057,0.42084065117869884,-0.8791073450641793,0.08107837999042887,-0.0606293056858646,-1.2984677625692256,-0.9526617479367557,1.1416579910536835,0.13593136335059053,-0.1790423277350827,1.8775608468012885,3.0940370861233606,-0.031744908526115174,0.5180573956646057,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.025199324650836994,1.0026222188239642,-1.3786049993712943,2.7295242300793277,-0.7355890326334656,0.21636733085825482,-0.5629231723307153,0.10863077097339395,4.132037847844936,-0.8067497779060742,0.9409952878769652,-0.4301759669868179,-0.7710198034073763,0.34579373996602075,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.18979526604543842,0.5655044371788908,0.813790292416791,0.053269504024264246,-0.0031371136066703498,1.0828619555333547,0.08107837999042887,-1.065237448909853,0.7701555617414707,-0.9898877670258749,1.41943529737493,0.42084065117869884,0.42084065117869884,1.2371500809699392,-1.5010550842325505,-0.2709736160130218,0.9409952878769652,0.8991926986389834,-0.9157349411807121,0.025199324650836994,-0.6656250951850902,1.063003214209736,-0.462913985518726,-0.3337570158659335,0.21636733085825482,-0.14899690656748693,-0.24003068040751657,1.5065684931882488,0.612209574085093,0.8353709145003145,0.5180573956646057,-0.30221572716540523,0.5655044371788908,0.16298471623624555,-0.9157349411807121,-1.419122462160247,-0.24003068040751657,-0.0606293056858646,0.08107837999042887,0.21636733085825482,-0.20938691832830006,-1.8845641737373735,1.102589523776575,0.10863077097339395,0.025199324650836994,1.383857498630824,-0.9898877670258749,-0.0606293056858646 3193 +Cytosolic large ribosomal subunit 31 47 2.4982156865942966 0.0124820223044126 P18124,P61254,P35268,P47914,Q02878,P62750,P39023,P61513,P62899,Q02543,Q9NP64,P83881,P18077,P26373,P61927,Q9Y3U8,P62910,P62424,P42766,P83731,P51116,Q07020,P63173,P46779,P36578,P84098,P62917,P61313,P46776,P46778,P40429 Localization GO Cellular component msigdb_gocc 878,755,999,509,630,1005,508,511,785,656,160,533,1035,1037,423,448,180,926,557,681,809,813,727,476,849,602,365,364,362,628,378 1254,2993,1035,878,1722,1037,1307,2678,2679,999,849,508,378,557,362,2071,628,476,509,1172,1826,809,755,364,1044,511,423,926,1005,1542,2123,785,1400,180,1543,365,727,681,533,602,656,630,813,2024,1601,160,448 0.21636733085825482,-1.3786049993712943,0.34579373996602075,0.44544306819693447,-0.0606293056858646,0.34579373996602075,0.18979526604543842,-0.8067497779060742,-0.8067497779060742,0.3710194511388473,0.4698445071041799,0.7480967979523666,0.8991926986389834,0.7034844439548688,0.9201671263885668,-0.2709736160130218,0.6352911062035237,0.7920526088666452,0.7480967979523666,0.26881271098746073,-0.11924966294507812,0.4940482237889104,0.5418751241716249,0.9201671263885668,0.34579373996602075,0.7480967979523666,0.856796727704752,0.42084065117869884,0.3710194511388473,0.053269504024264246,-0.30221572716540523,0.5180573956646057,0.13593136335059053,1.3478507399601813,0.053269504024264246,0.9201671263885668,0.5655044371788908,0.5889482912953588,0.7258739119100094,0.6581956434453833,0.612209574085093,0.6352911062035237,0.4940482237889104,-0.24003068040751657,0.025199324650836994,1.4545942332074184,0.8353709145003145 3193 +Metabolism of steroids 10 45 2.4959437536352698 0.0125622519009529 O14734,P48449,Q9BWD1,P30536,Q15392,Q9UBM7,Q14739,Q16850,O95487,P04062 Processes and pathways Reactome Pathways msigdb_reactome 251,99,4,100,70,141,175,93,213,158 2051,506,251,1564,995,213,507,158,2397,2116,2318,2065,3102,100,1573,1091,99,1577,2167,2511,1870,784,2516,2862,1641,1320,175,294,2836,1879,1834,70,1455,1739,1880,381,93,732,1886,1329,942,4,2767,667,141 -0.2709736160130218,0.7480967979523666,1.102589523776575,0.025199324650836994,0.3710194511388473,1.1993188415722877,0.7480967979523666,1.4545942332074184,-0.5292875863064875,-0.30221572716540523,-0.462913985518726,-0.2709736160130218,-1.8407550802597537,1.8007392900685555,0.025199324650836994,0.3203531886001632,1.8317054739763257,0.025199324650836994,-0.3337570158659335,-0.631091924935383,-0.14899690656748693,0.5180573956646057,-0.631091924935383,-1.065237448909853,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,-1.0274130001280428,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,0.10863077097339395,-0.0606293056858646,-0.14899690656748693,0.8991926986389834,1.9077445032407137,0.5655044371788908,-0.14899690656748693,0.18979526604543842,0.42084065117869884,4.665813426727727,-0.9157349411807121,0.612209574085093,1.5576536448951719 3193 +Glycosylation 12 44 2.4955202418386064 0.0125772579134366 Q9H488,O43505,Q2TAA5,O60476,Q9BV10,O15294,O60502,O15118,Q8WTW3,O75503,Q9BT22,P04062 Processes and pathways GO Biological process msigdb_gobp 230,39,108,419,115,174,300,208,245,184,91,158 2421,208,174,2639,39,419,300,2113,2056,1563,184,2311,158,1819,1440,2276,1171,1448,1922,2242,1971,814,2286,1318,789,108,658,1459,1224,2600,245,1413,828,91,115,2768,230,1192,469,2417,947,1340,1759,2157 -0.5629231723307153,1.2182943630695027,1.3659083845750073,-0.7710198034073763,2.7180994529009332,0.856796727704752,1.0228851550061475,-0.30221572716540523,-0.2709736160130218,0.025199324650836994,1.3296832447901088,-0.462913985518726,1.4545942332074184,-0.11924966294507812,0.10863077097339395,-0.4301759669868179,0.26881271098746073,0.10863077097339395,-0.1790423277350827,-0.3977371338220593,-0.20938691832830006,0.4940482237889104,-0.4301759669868179,0.18979526604543842,0.5180573956646057,1.7536794627358119,0.612209574085093,0.10863077097339395,0.2427051145911597,-0.7004574638193659,1.1221876398575348,0.13593136335059053,0.4940482237889104,1.9227226839549494,1.6735598720423626,-0.9157349411807121,1.1802219848882647,0.26881271098746073,0.813790292416791,-0.5292875863064875,0.42084065117869884,0.18979526604543842,-0.0606293056858646,-0.30221572716540523 3193 +Cross presentation of soluble exogenous antigens endosomes 7 37 2.4949200582077675 0.0125985510030131 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Degradation of axin 7 37 2.4949200582077675 0.0125985510030131 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Endocytosis 41 118 2.489576702502696 0.0127895318214585 Q9NVZ3,O95782,O00429,Q9H4M9,Q8WTV0,O43426,Q08380,O60749,P22681,A0FGR8,Q13432,Q9UL25,P62820,P50897,Q9UKG1,Q9H223,Q9UHD9,Q9UBF8,O60784,P50570,Q14108,Q9UQ16,P57105,O15260,P62993,Q5VW38,Q13464,Q99816,O15118,Q5KU26,Q9Y5X3,Q7Z6M1,O15126,Q15036,Q9NX40,Q9Y2T2,Q9P2D3,Q14457,Q9UNF0,P41440,P02786 Processes and pathways GO Biological process msigdb_gobp 524,627,505,546,18,650,535,274,780,772,31,299,532,37,569,567,704,432,420,559,51,838,317,804,440,65,687,739,208,342,872,217,594,367,373,503,250,493,391,243,749 772,1241,1761,505,1122,1480,208,594,804,650,1958,274,420,2540,2309,2059,627,749,1720,1441,1864,1769,1162,845,2830,2063,2995,1570,998,1773,780,2234,2399,1168,1260,243,1170,1394,2431,559,37,1396,1629,1869,1497,1731,317,1356,1871,1921,1398,532,440,2370,2626,1687,1635,1734,1785,1359,3105,535,31,687,2128,2374,51,2942,1833,493,970,1453,367,1322,2712,2714,1882,2288,342,1740,65,1219,2809,217,1593,2091,2092,18,1890,1846,980,2142,1142,739,3058,567,1376,546,524,373,250,1151,1292,432,704,1710,2151,569,299,2390,1472,391,838,503,903,1029,872,2462 0.5180573956646057,0.21636733085825482,-0.08979570423491805,0.7480967979523666,0.29469410743066005,0.08107837999042887,1.2182943630695027,0.6581956434453833,0.4940482237889104,0.612209574085093,-0.20938691832830006,1.063003214209736,0.856796727704752,-0.6656250951850902,-0.462913985518726,-0.2709736160130218,0.6352911062035237,0.5418751241716249,-0.0606293056858646,0.10863077097339395,-0.14899690656748693,-0.08979570423491805,0.26881271098746073,0.4698445071041799,-1.0274130001280428,-0.2709736160130218,-1.3786049993712943,0.025199324650836994,0.3710194511388473,-0.08979570423491805,0.5180573956646057,-0.3977371338220593,-0.5292875863064875,0.26881271098746073,0.21636733085825482,1.1221876398575348,0.26881271098746073,0.13593136335059053,-0.5629231723307153,0.7034844439548688,2.8414299150165303,0.13593136335059053,-0.0031371136066703498,-0.14899690656748693,0.08107837999042887,-0.0606293056858646,1.0026222188239642,0.16298471623624555,-0.14899690656748693,-0.1790423277350827,0.13593136335059053,0.7258739119100094,0.8353709145003145,-0.49595119132772597,-0.7355890326334656,-0.031744908526115174,-0.0031371136066703498,-0.0606293056858646,-0.08979570423491805,0.16298471623624555,-1.8407550802597537,0.7258739119100094,2.9809050828258044,0.5889482912953588,-0.30221572716540523,-0.49595119132772597,2.391845426042903,-1.2195274337089115,-0.11924966294507812,0.7701555617414707,0.39603391908014063,0.10863077097339395,0.9201671263885668,0.18979526604543842,-0.8427789578797747,-0.8427789578797747,-0.14899690656748693,-0.4301759669868179,0.9616792082789943,-0.0606293056858646,2.193900422541388,0.2427051145911597,-0.9898877670258749,1.1993188415722877,0.025199324650836994,-0.2709736160130218,-0.2709736160130218,3.4188452578218076,-0.14899690656748693,-0.11924966294507812,0.39603391908014063,-0.30221572716540523,0.29469410743066005,0.5655044371788908,-1.5841846451243686,0.7034844439548688,0.16298471623624555,0.7258739119100094,0.7480967979523666,0.9201671263885668,1.1221876398575348,0.29469410743066005,0.21636733085825482,0.856796727704752,0.5889482912953588,-0.031744908526115174,-0.30221572716540523,0.7034844439548688,1.0430115443451933,-0.49595119132772597,0.10863077097339395,0.8991926986389834,0.4940482237889104,0.7701555617414707,0.44544306819693447,0.3710194511388473,0.4698445071041799,-0.5629231723307153 3193 +Epithelial cell proliferation 10 42 2.484919048029652 0.0129580897714109 P09429,Q86VI3,Q9NQC3,P09601,P26583,Q8WTV0,Q9H2J4,Q12959,P57105,P06400 Processes and pathways GO Biological process msigdb_gobp 312,296,195,7,107,18,248,121,317,277 1030,2270,1563,1670,1817,2853,277,312,7,349,2830,1771,2779,107,1168,720,1040,1493,317,963,1356,1006,1634,534,2200,2437,121,2709,2756,1739,2177,2630,296,18,1461,1649,2450,1414,248,195,984,1860 0.34579373996602075,-0.4301759669868179,0.025199324650836994,-0.031744908526115174,-0.11924966294507812,-1.065237448909853,1.063003214209736,1.0026222188239642,4.132037847844936,0.9409952878769652,-1.0274130001280428,-0.08979570423491805,-0.9526617479367557,1.7536794627358119,0.26881271098746073,0.5655044371788908,0.34579373996602075,0.08107837999042887,1.0026222188239642,0.39603391908014063,0.16298471623624555,0.3710194511388473,-0.0031371136066703498,0.7258739119100094,-0.3655974840969154,-0.5629231723307153,1.6409002994968682,-0.8427789578797747,-0.9157349411807121,-0.0606293056858646,-0.3337570158659335,-0.7355890326334656,1.0430115443451933,3.4188452578218076,0.10863077097339395,-0.0031371136066703498,-0.5629231723307153,0.13593136335059053,1.1221876398575348,1.2930133010682965,0.39603391908014063,-0.11924966294507812 3193 +Transcriptional regulation by runx2 16 51 2.482366533514382 0.0130512949729917 P51665,Q14997,P49721,P28074,P61289,P06493,O43242,P14635,P28072,P25787,P28070,P11802,O00231,P06400,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 352,167,8,105,478,236,417,209,20,119,55,215,525,277,30,95 525,2356,1907,2050,1993,417,913,277,236,2731,215,209,1916,95,2467,119,2162,2468,2234,2400,55,20,105,1168,529,2996,1493,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,167,929,2449,795,2143,1523,3089,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.063003214209736,1.1416579910536835,-0.8791073450641793,1.1993188415722877,1.2182943630695027,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.3977371338220593,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.26881271098746073,0.7258739119100094,-1.3786049993712943,0.08107837999042887,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.5629231723307153,0.5180573956646057,-0.30221572716540523,0.08107837999042887,-1.7540346313524435,0.21636733085825482 3193 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 15 51 2.4786568382901955 0.0131878117468604 P51665,Q14997,P49721,P28074,P61289,Q9H1A4,Q16763,Q12834,O43242,P28072,P25787,P28070,P06400,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 352,167,8,105,478,522,368,457,417,20,119,55,277,30,95 525,2356,1907,2050,1993,2422,417,913,277,1916,95,2467,119,2162,2468,2400,55,20,105,1865,2996,2998,1261,1446,8,352,723,3068,30,478,1631,2434,2802,729,457,1008,1545,1639,167,929,368,2297,795,2143,522,2109,1807,1522,2537,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,-0.5629231723307153,0.856796727704752,0.42084065117869884,1.063003214209736,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.14899690656748693,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,0.5655044371788908,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.813790292416791,0.3710194511388473,0.053269504024264246,-0.0031371136066703498,1.41943529737493,0.42084065117869884,0.9201671263885668,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.7480967979523666,-0.2709736160130218,-0.08979570423491805,0.08107837999042887,-0.631091924935383,0.08107837999042887,0.21636733085825482 3193 +Endothelial cell migration 8 35 2.4767980558431333 0.0132566885667517 P09429,P14923,P09601,P42785,Q8WTV0,P57105,P04792,Q4VCS5 Processes and pathways GO Biological process msigdb_gobp 312,290,7,9,18,317,185,28 1122,1030,572,2795,1563,625,1567,185,1441,1962,1348,312,7,290,1771,2779,2547,1260,1493,9,922,2737,2780,317,1500,340,3027,635,28,2288,18,942,3071,2148,1947 0.29469410743066005,0.34579373996602075,0.680925878721421,-0.9898877670258749,0.025199324650836994,0.6352911062035237,0.025199324650836994,1.3296832447901088,0.10863077097339395,-0.20938691832830006,0.16298471623624555,1.0026222188239642,4.132037847844936,1.0430115443451933,-0.08979570423491805,-0.9526617479367557,-0.6656250951850902,0.21636733085825482,0.08107837999042887,4.117747886511145,0.42084065117869884,-0.8791073450641793,-0.9526617479367557,1.0026222188239642,0.08107837999042887,0.9616792082789943,-1.459939156603208,0.6352911062035237,3.0328607875428633,-0.4301759669868179,3.4188452578218076,0.42084065117869884,-1.6685111568748416,-0.30221572716540523,-0.1790423277350827 3193 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 10 32 2.471694941565377 0.0134474211981681 Q15800,Q32P28,O15460,P30519,P09601,P13674,O75592,Q8NB78,Q6UW02,Q16850 Functions GO Molecular function msigdb_gomf 381,132,375,6,7,199,451,279,442,93 2421,506,375,1960,2113,451,1564,1253,1486,7,199,2507,6,807,655,2242,2861,1320,381,93,132,1219,1366,442,856,1183,279,2947,2531,2492,1473,2538 -0.5629231723307153,0.7480967979523666,0.8991926986389834,-0.20938691832830006,-0.30221572716540523,0.813790292416791,0.025199324650836994,0.21636733085825482,0.08107837999042887,4.132037847844936,1.2558874980500507,-0.631091924935383,4.195509236421808,0.4940482237889104,0.612209574085093,-0.3977371338220593,-1.065237448909853,0.18979526604543842,0.8991926986389834,1.9077445032407137,1.574489660490009,0.2427051145911597,0.16298471623624555,0.8353709145003145,0.4698445071041799,0.26881271098746073,1.063003214209736,-1.2195274337089115,-0.631091924935383,-0.5968579512594566,0.10863077097339395,-0.631091924935383 3193 +Abnormality of exocrine pancreas physiology 9 21 2.4685520356170545 0.0135660926581828 Q9UKG1,P09601,Q9UHX1,Q9UJW0,Q15904,P48506,Q8IWV7,P14174,O00330 Drugs and Diseases Human Phenotype Ontology msigdb_hp 569,7,135,240,460,578,495,242,486 486,2773,7,242,2366,1574,1040,1209,578,1173,2197,460,636,1841,495,2210,135,240,569,1617,1475 0.7701555617414707,-0.9526617479367557,4.132037847844936,1.1221876398575348,-0.49595119132772597,0.025199324650836994,0.34579373996602075,0.2427051145911597,0.680925878721421,0.26881271098746073,-0.3655974840969154,0.813790292416791,0.6352911062035237,-0.11924966294507812,0.7701555617414707,-0.3655974840969154,1.574489660490009,1.1416579910536835,0.7034844439548688,0.025199324650836994,0.10863077097339395 3193 +Disproportionate short limb short stature 12 24 2.4672139766673857 0.0136168959452667 P42345,Q6DKJ4,Q32P28,Q03164,Q8WVQ1,Q15392,Q9UBM7,Q14739,Q9BV10,Q7LGA3,Q8WTW3,O75718 Drugs and Diseases Human Phenotype Ontology msigdb_hp 530,516,132,68,332,70,141,175,115,637,245,394 1156,1031,2822,394,676,2937,530,1094,68,1736,1977,175,1879,70,132,516,637,1369,245,332,1464,2528,115,141 0.26881271098746073,0.34579373996602075,-1.0274130001280428,0.8780699365084367,0.5889482912953588,-1.2195274337089115,0.7258739119100094,0.3203531886001632,2.1802255667070183,-0.0606293056858646,-0.20938691832830006,1.3659083845750073,-0.14899690656748693,2.1802255667070183,1.574489660490009,0.7480967979523666,0.6352911062035237,0.16298471623624555,1.1221876398575348,0.9822208710006587,0.10863077097339395,-0.631091924935383,1.6735598720423626,1.5576536448951719 3193 +Cation transmembrane transport 18 118 2.465701090079451 0.0136745394459438 Q7KZN9,P78417,Q12959,P62942,Q9Y6M7,P13073,Q9Y619,Q9UDW1,Q96ES6,P42858,Q9H936,O95202,Q9HC21,O75964,Q8TAD4,O43772,Q70HW3,P21796 Processes and pathways GO Biological process msigdb_gobp 192,1,121,148,102,253,72,59,12,155,78,262,112,81,280,23,88,26 1762,1763,1247,23,1716,673,1344,2674,3084,2613,81,262,1817,959,2991,2644,1720,1161,1441,1962,1864,2231,2969,2061,651,2115,1087,527,253,1821,2063,1771,2647,1166,3009,2649,2545,26,554,2779,577,3034,2957,2508,1866,1723,1208,2959,155,1394,1395,1093,2701,559,1869,2369,1211,1827,1355,2554,2074,1045,148,1,3026,1733,1687,1874,1359,1688,2438,121,458,2656,1268,2865,1504,2712,1835,1589,88,192,2810,1105,2898,2961,2599,280,587,1113,12,2411,2605,1372,2946,1414,465,1894,2575,698,2768,1190,1852,78,1234,469,112,483,2847,1290,59,1340,1710,1558,310,1905,72,102 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3193 +Synaptic vesicle localization 8 13 2.462194037209793 0.0138089936664922 O00203,O95295,Q9Y2T2,P50570,O14617,P78537,O43426,Q96A57 Processes and pathways GO Biological process msigdb_gobp 472,347,503,559,415,680,650,319 472,415,650,347,1164,1572,720,559,680,1687,2128,319,503 0.7920526088666452,0.856796727704752,0.612209574085093,0.9409952878769652,0.26881271098746073,0.025199324650836994,0.5655044371788908,0.7034844439548688,0.5889482912953588,-0.031744908526115174,-0.30221572716540523,1.0026222188239642,0.7701555617414707 3193 +Proteasome 12 36 2.461634164662764 0.0138305659076474 P51665,Q14997,P49721,P28074,P61289,Q9Y244,O43242,P28072,P25787,P28070,P60900,P20618 Processes and pathways KEGG Pathways msigdb_kegg 352,167,8,105,478,502,417,20,119,55,30,95 525,2356,2050,1993,417,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295,502 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525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,1048,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.34579373996602075,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Regulation of ras by gaps 7 38 2.461607507387292 0.0138315937709576 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,1048,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.34579373996602075,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Vitamin metabolic process 9 29 2.453053209565039 0.0141649383974147 P09455,P78417,Q9H2D1,Q9NRN7,P00374,Q99707,Q9HC21,P41440,P04062 Processes and pathways GO Biological process msigdb_gobp 128,1,35,239,14,308,112,243,158 1815,1670,14,158,128,2695,2364,2003,3169,1259,337,2938,1091,243,578,629,1,2340,1647,1226,1282,2976,1284,942,308,35,112,239,3143 -0.11924966294507812,-0.031744908526115174,3.902465612713916,1.4545942332074184,1.6078795867372875,-0.8427789578797747,-0.49595119132772597,-0.24003068040751657,-2.9747685245557376,0.21636733085825482,0.9616792082789943,-1.2195274337089115,0.3203531886001632,1.1221876398575348,0.680925878721421,0.6352911062035237,5.401623940688195,-0.462913985518726,-0.0031371136066703498,0.2427051145911597,0.21636733085825482,-1.2984677625692256,0.21636733085825482,0.42084065117869884,1.0228851550061475,2.863316355216428,1.7058661157411827,1.1416579910536835,-2.2458099647275738 3193 +Sterol biosynthetic process 6 24 2.4506249930819486 0.0142608440284988 P48449,Q15392,Q9UBM7,Q9UKR5,P42765,Q16850 Processes and pathways GO Biological process msigdb_gobp 99,70,141,143,61,93 1564,2729,3092,507,1087,2397,2507,1573,61,99,1782,2511,2516,1641,1320,175,1879,1834,70,1880,381,93,141,143 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0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Auf1 hnrnp d0 binds and destabilizes mrna 8 42 2.4450318377225027 0.0144839355394721 Q14997,P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 167,8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,185,1255,918,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,492,729,1545,2172,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.3296832447901088,0.21636733085825482,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.7701555617414707,0.5655044371788908,0.053269504024264246,-0.3337570158659335,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Tnfr2 non canonical nf kb pathway 7 42 2.4426799875956515 0.0145786580350635 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,989,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,1212,478,1631,2434,2802,1266,729,1545,1584,167,929,1889,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.2427051145911597,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.14899690656748693,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Metabolism of polyamines 7 39 2.4369912594479293 0.0148100373381938 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,1966,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,2281,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,-0.20938691832830006,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.4301759669868179,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Cytochrome complex assembly 6 13 2.429045081634317 0.0151386498217487 Q7KZN9,Q9BSK2,Q15070,Q69YU5,Q6DKK2,Q9Y2R0 Processes and pathways GO Biological process msigdb_gobp 192,255,326,138,172,116 1766,2360,1093,363,326,138,172,192,860,2575,255,1198,116 -0.08979570423491805,-0.49595119132772597,0.3203531886001632,0.9201671263885668,0.9822208710006587,1.5576536448951719,1.383857498630824,1.2930133010682965,0.4698445071041799,-0.6656250951850902,1.102589523776575,0.26881271098746073,1.6735598720423626 3193 +Regulation of runx3 expression and activity 6 37 2.4272462847272616 0.0152139239816182 P49721,P28074,P28072,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,1209,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Cytosolic transport 40 66 2.4266476616954606 0.0152390475148482 O95782,O60499,Q96QK1,P53367,Q9UID3,Q9C0C9,Q4KMP7,O60493,P35241,O60749,Q4J6C6,Q9UL25,O60271,O15498,P42566,P28482,O94832,O75503,Q99570,O15260,Q8IWJ2,P49257,Q7Z3U7,Q9Y5X3,P61106,Q8IUD2,O75436,P15311,Q13190,Q9H3S7,Q96RL7,P40616,Q9P2R3,Q14457,Q9P2D3,Q8N2H4,Q14203,P26038,Q9UNK0,P20339 Processes and pathways GO Biological process msigdb_gobp 627,376,1185,137,801,1067,541,774,396,274,1055,299,907,286,1170,1168,675,184,1230,804,462,961,210,872,965,357,843,845,226,1145,497,488,1151,493,250,1136,758,1126,124,998 1714,1480,804,286,1958,907,774,376,274,2540,843,2497,184,675,1386,627,1915,845,998,2545,1126,2234,1168,1572,396,2068,488,1170,961,1629,137,2654,965,2885,1635,2200,1360,226,2374,758,493,1322,1055,541,210,357,462,1136,1699,1892,1185,497,1230,2349,1067,1145,2458,250,1151,1660,801,1856,299,1237,124,872 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3193 +Mitochondrion organization 54 189 2.4263725521218245 0.015250605799679 Q9BSK2,O00429,O14737,Q69YU5,Q16543,Q96CU9,Q8N4H5,O95202,O60830,Q9NUQ9,Q9NS69,Q7Z3C6,O95429,P21796,O75306,P42858,P04062,Q99595,Q9NVT9,P53365,P45880,Q13505,O14925,P14406,Q16611,Q6DKK2,Q9NQ88,Q96A26,Q9Y6C9,P42765,Q6UXV4,O43676,P17152,Q15070,Q15388,Q04837,Q5JRX3,A6NDU8,Q9UDX5,Q9BWH2,Q5T9A4,P30536,P55786,O00203,Q8IWA4,O75153,Q96RL7,Q9Y2R0,Q8N2A8,Q9P0J0,P30419,Q9GZY8,Q14457,Q9H061 Processes and pathways GO Biological process msigdb_gobp 255,505,252,138,266,408,142,262,17,284,24,278,395,26,526,155,158,32,163,164,38,166,169,42,171,172,178,181,182,61,203,73,200,326,205,456,84,449,89,482,354,100,101,472,233,106,497,116,386,249,361,247,493,126 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3193 +Lipid homeostasis 10 24 2.4249480543853865 0.0153105773130186 P09455,Q9NQC3,P35610,Q86YV9,Q8WTV0,O15118,Q5BJF2,Q9Y6C9,Q9BWH2,P34913 Processes and pathways GO Biological process msigdb_gobp 128,195,324,307,18,208,117,182,482,190 2582,208,804,995,128,997,1258,190,324,1131,2862,972,117,1740,1365,307,18,482,546,667,195,1120,2692,182 -0.7004574638193659,1.2182943630695027,0.4940482237889104,0.3710194511388473,1.6078795867372875,0.3710194511388473,0.21636733085825482,1.2930133010682965,0.9822208710006587,0.29469410743066005,-1.065237448909853,0.39603391908014063,1.6572747340816105,-0.0606293056858646,0.16298471623624555,1.0228851550061475,3.4188452578218076,0.7920526088666452,0.7258739119100094,0.612209574085093,1.2930133010682965,0.3203531886001632,-0.8067497779060742,1.3478507399601813 3193 +Mapk6 mapk4 signaling 13 49 2.420749103232247 0.0154885632701891 Q9HCE1,P51665,Q14997,P49721,P28074,P06493,O43242,P28072,P25787,P28070,P04792,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 298,352,167,8,105,236,417,20,119,55,185,30,95 525,2356,1907,2050,1993,1624,417,913,185,2853,236,1916,95,1167,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,1356,478,1631,2434,2802,729,685,1545,167,929,1363,1409,795,2143,298,1805,1523,1295,707 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34 2.414907818367503 0.0157391924226848 O00429,P53365,P30536,Q16543,P42858,Q9NQ88,Q14457,A6NDU8,Q7Z3C6,Q9BWH2,P21796,P04062 Processes and pathways GO Biological process msigdb_gobp 505,164,100,266,155,178,493,449,278,482,26,158 449,1619,505,1909,2730,158,2773,1161,527,1165,26,100,155,1129,721,2882,164,1397,1833,493,266,1458,278,1460,2719,2032,2946,1414,482,178,945,1521,984,1663 0.813790292416791,-0.0031371136066703498,0.7480967979523666,-0.1790423277350827,-0.8791073450641793,1.4545942332074184,-0.9526617479367557,0.26881271098746073,0.7258739119100094,0.26881271098746073,3.0940370861233606,1.8007392900685555,1.4720196860623391,0.29469410743066005,0.5655044371788908,-1.103361115024735,1.41943529737493,0.13593136335059053,-0.11924966294507812,0.7701555617414707,1.0828619555333547,0.10863077097339395,1.063003214209736,0.10863077097339395,-0.8427789578797747,-0.24003068040751657,-1.2195274337089115,0.13593136335059053,0.7920526088666452,1.3659083845750073,0.42084065117869884,0.08107837999042887,0.39603391908014063,-0.0031371136066703498 3193 +Runx1 regulates transcription of genes involved in differentiation of hscs 8 42 2.414593765039354 0.0157527678423587 Q03164,P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 68,8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,3067,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,2803,1685,68,729,1545,167,929,2298,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-1.6685111568748416,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.9898877670258749,-0.031744908526115174,2.1802255667070183,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Cellular ion homeostasis 22 87 2.4143532929934595 0.0157631695636095 P78417,P09601,Q8N511,Q92544,O95202,Q9Y487,Q8TAD4,P62942,P42858,P50897,Q16611,Q9UM00,O14617,Q7L0J3,O75503,O76003,P09429,Q9HC07,Q15904,Q9HD20,Q9Y6M7,O95295 Processes and pathways GO Biological process msigdb_gobp 1,7,139,407,262,153,280,148,155,37,171,310,415,53,184,187,312,469,460,483,102,347 472,415,1763,1766,1716,672,673,184,2360,187,1767,262,3019,347,749,2991,2644,1720,2114,1962,2645,2969,312,7,2396,2503,1088,2778,1821,2063,1771,2647,576,2234,3034,2547,1168,2508,2959,155,37,1629,1781,1869,2196,2369,1211,2554,1045,148,1,3026,1687,1785,2656,1975,1504,2712,460,171,1881,53,2810,1105,139,2599,280,587,407,793,826,1371,2605,2098,1894,1190,700,469,483,1340,1710,1558,310,153,1905,987,102 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3193 +Negative regulation of notch4 signaling 6 40 2.41172596194879 0.0158772100706947 P49721,P28074,P28072,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1499,1266,729,1545,1584,929,795,2143,1523,1295,2224 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.08107837999042887,0.21636733085825482,0.5655044371788908,0.053269504024264246,0.025199324650836994,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.3655974840969154 3193 +protease 6 41 2.408786036969432 0.0160056784412714 P49721,P28074,P28072,P28070,P60900,P20618 Functions Panther Protein class panther_protein_class 8,105,20,55,30,95 2356,1907,1993,417,1124,1816,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2012,2998,1261,1446,8,1825,3068,30,1097,1631,2434,2802,1545,1738,1223,795,2143,943,982,944,3081,1295,744,1902 -0.49595119132772597,-0.1790423277350827,-0.24003068040751657,0.856796727704752,0.29469410743066005,-0.11924966294507812,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-0.24003068040751657,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,-0.11924966294507812,-1.6685111568748416,3.0017959971834336,0.3203531886001632,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.053269504024264246,-0.0606293056858646,0.2427051145911597,0.5180573956646057,-0.30221572716540523,0.42084065117869884,0.39603391908014063,0.42084065117869884,-1.7111232730375066,0.21636733085825482,0.5655044371788908,-0.14899690656748693 3193 +Entry into host 6 32 2.4069513558094013 0.0160863123674577 P19474,P06493,O00505,Q8WTV0,Q14108,O15118 Processes and pathways GO Biological process msigdb_gobp 43,236,261,18,51,208 261,1030,208,774,749,1441,236,1486,2061,2994,1443,1915,1391,43,780,2426,1000,1170,2432,1829,2015,1689,51,1503,1835,18,1936,2298,1595,320,837,2850 1.0828619555333547,0.34579373996602075,1.2182943630695027,0.5180573956646057,0.5418751241716249,0.10863077097339395,1.1416579910536835,0.08107837999042887,-0.2709736160130218,-1.3786049993712943,0.10863077097339395,-0.1790423277350827,0.13593136335059053,2.6013806888194835,0.5180573956646057,-0.5629231723307153,0.3710194511388473,0.26881271098746073,-0.5629231723307153,-0.11924966294507812,-0.24003068040751657,-0.031744908526115174,2.391845426042903,0.08107837999042887,-0.11924966294507812,3.4188452578218076,-0.1790423277350827,-0.4301759669868179,0.025199324650836994,1.0026222188239642,0.4940482237889104,-1.0274130001280428 3193 +Antigen processing ubiquitination proteasome degradation 22 90 2.403950437606285 0.0162189720436971 P49721,P28072,Q9UBS8,P60900,Q14997,P19474,Q9UIQ6,O43242,P28070,Q12834,P61088,P61289,P20618,P51665,P49427,P55786,P28074,Q7Z7E8,Q16763,Q8IWV7,P25787,Q9H1A4 Processes and pathways Reactome Pathways msigdb_reactome 8,20,21,30,167,43,47,417,55,457,455,478,95,352,477,101,105,237,368,495,119,522 1952,525,2356,1907,2050,1993,417,913,626,1532,2642,1916,43,95,2735,2467,119,2162,2468,2400,55,20,105,2235,1865,2996,2998,1394,1261,477,1446,8,352,2325,3068,101,30,1212,754,455,478,1631,2434,2802,1266,1213,1785,729,457,1008,1545,1639,1584,603,1048,928,2243,167,929,1693,2627,3099,1407,368,3038,932,761,1460,237,495,1889,792,1113,2298,795,2143,1067,522,799,21,47,2109,1807,1522,2537,1523,1076,3089,1295,902 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3193 +Downstream signaling events of b cell receptor bcr 8 46 2.3953269998881885 0.0166055484328246 P49721,P28074,P28072,P25787,P28070,P62942,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,148,30,95 525,2356,1907,2050,1993,989,417,913,1387,2114,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,148,1266,756,729,3105,1545,1584,167,929,795,2143,1523,1295,1760 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,0.13593136335059053,-0.30221572716540523,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.5065684931882488,0.21636733085825482,0.5418751241716249,0.5655044371788908,-1.8407550802597537,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.0606293056858646 3193 +Intrinsic component of mitochondrial membrane 13 47 2.393170261017114 0.0167034878299054 Q99595,Q13505,Q6UXV4,O14925,P17152,Q16611,Q8IWA4,Q15388,Q9HC21,O60830,Q9Y2R0,Q9GZY8,P57105 Localization GO Cellular component msigdb_gocc 32,166,203,169,200,171,233,205,112,17,116,247,317 169,1766,17,2541,2360,2728,2730,1388,527,200,3118,2981,2324,317,1733,166,326,205,819,171,1881,2628,1838,2026,203,233,2915,2563,2599,2032,1372,32,1894,1467,482,247,1114,1234,2667,112,2873,1023,1291,1855,116,1905,1476 1.383857498630824,-0.08979570423491805,3.6453743945093926,-0.6656250951850902,-0.49595119132772597,-0.8791073450641793,-0.8791073450641793,0.13593136335059053,0.7258739119100094,1.2558874980500507,-1.9730801058799055,-1.3383867666926692,-0.462913985518726,1.0026222188239642,-0.0606293056858646,1.41943529737493,0.9822208710006587,1.2371500809699392,0.4940482237889104,1.383857498630824,-0.14899690656748693,-0.7355890326334656,-0.11924966294507812,-0.24003068040751657,1.2558874980500507,1.1610022318711952,-1.1417840001131578,-0.6656250951850902,-0.7004574638193659,-0.24003068040751657,0.16298471623624555,2.9598669449402526,-0.14899690656748693,0.10863077097339395,0.7920526088666452,1.1221876398575348,0.3203531886001632,0.2427051145911597,-0.7710198034073763,1.7058661157411827,-1.065237448909853,0.3710194511388473,0.21636733085825482,-0.11924966294507812,1.6735598720423626,-0.14899690656748693,0.10863077097339395 3193 +Sphingolipid metabolism 9 26 2.391274039969999 0.0167900154965416 P07602,Q96G23,P16278,Q06136,Q13510,Q9NZJ7,Q16880,P10619,P04062 Processes and pathways Reactome Pathways msigdb_reactome 67,41,263,16,50,321,188,60,158 772,1668,1381,624,3019,574,158,996,1389,67,2645,60,2365,263,350,2318,599,16,50,188,3136,41,2722,1235,321,2691 0.5180573956646057,-0.031744908526115174,0.13593136335059053,0.6352911062035237,-1.459939156603208,0.680925878721421,1.4545942332074184,0.3710194511388473,0.13593136335059053,2.1802255667070183,-0.7710198034073763,2.261350745716217,-0.49595119132772597,1.0828619555333547,0.9409952878769652,-0.462913985518726,0.6581956434453833,3.703535835976282,2.4045866103244666,1.3114045548408733,-2.153702990291578,2.671958061458734,-0.8427789578797747,0.2427051145911597,1.0026222188239642,-0.8067497779060742 3193 +G1 to s cell cycle control 14 27 2.391118326613725 0.016797138403451 P49642,P33991,Q07864,Q13416,Q9Y619,P24941,Q9UBD5,P06493,P14635,O75419,P35244,P11802,P06400,Q14566 Processes and pathways WikiPathways msigdb_wp 598,719,225,632,72,422,800,236,209,301,397,215,277,293 906,301,2773,277,236,215,2828,209,1163,422,781,1676,719,1627,1038,397,1209,598,1311,1494,1634,225,632,293,2573,800,72 0.42084065117869884,1.0228851550061475,-0.9526617479367557,1.063003214209736,1.1416579910536835,1.1993188415722877,-1.0274130001280428,1.2182943630695027,0.26881271098746073,0.856796727704752,0.5180573956646057,-0.031744908526115174,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,0.2427051145911597,0.6581956434453833,0.18979526604543842,0.08107837999042887,-0.0031371136066703498,1.1802219848882647,0.6352911062035237,1.0430115443451933,-0.6656250951850902,0.5180573956646057,2.166487793701175 3193 +Dectin 1 mediated noncanonical nf kb signaling 7 43 2.390356103035247 0.0168320436262727 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,989,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,1212,478,1631,2434,2802,1266,756,729,1545,1584,167,929,1889,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.2427051145911597,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5418751241716249,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-0.14899690656748693,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Signaling by notch4 6 42 2.387147868721351 0.0169796602669376 P49721,P28074,P28072,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1499,1266,729,1545,1047,1584,929,1461,795,2143,1523,1295,2224 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P51665,P49721,P28074,P61289,P24941,O43242,P28072,P25787,P28070,P11802,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 352,8,105,478,422,417,20,119,55,215,30,95 525,2356,1907,2050,1993,417,913,215,1916,95,422,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,1.1993188415722877,-0.1790423277350827,1.8775608468012885,0.856796727704752,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Protein targeting to mitochondrion 11 48 2.383356342689944 0.0171555788894834 Q99595,P30536,P55786,O14925,Q15388,Q8N4H5,O60830,Q9P0J0,Q5JRX3,Q9GZY8,Q9NS69 Processes and pathways GO Biological process msigdb_gobp 32,100,101,169,205,142,17,249,84,247,24 1619,1430,252,169,1909,711,17,3084,2728,2730,2642,395,1346,713,1388,915,3041,1165,100,2618,961,1129,1781,101,1213,855,205,1788,2560,2628,84,1460,142,2811,738,32,831,247,2668,24,249,1521,2743,984,2820,1476,2393,802 -0.0031371136066703498,0.10863077097339395,1.102589523776575,1.383857498630824,-0.1790423277350827,0.5655044371788908,3.6453743945093926,-1.7540346313524435,-0.8791073450641793,-0.8791073450641793,-0.7710198034073763,0.8780699365084367,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.42084065117869884,-1.5424702465695177,0.26881271098746073,1.8007392900685555,-0.7355890326334656,0.39603391908014063,0.29469410743066005,-0.08979570423491805,1.8007392900685555,0.2427051145911597,0.4698445071041799,1.2371500809699392,-0.08979570423491805,-0.6656250951850902,-0.7355890326334656,2.0110474795908226,0.10863077097339395,1.5407221737348815,-0.9898877670258749,0.5655044371788908,2.9598669449402526,0.4940482237889104,1.1221876398575348,-0.7710198034073763,3.193291468873368,1.1221876398575348,0.08107837999042887,-0.8791073450641793,0.39603391908014063,-0.9898877670258749,0.10863077097339395,-0.49595119132772597,0.5180573956646057 3193 +Cholesterol binding 6 13 2.377440879770348 0.0174332373258396 Q14849,P30536,P45880,Q14108,O15118,P21796 Functions GO Molecular function msigdb_gomf 294,100,38,51,208,26 208,2729,2969,26,2065,100,324,38,1131,51,294,1232,2767 1.2182943630695027,-0.8791073450641793,-1.2984677625692256,3.0940370861233606,-0.2709736160130218,1.8007392900685555,0.9822208710006587,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121 3193 +Stabilization of p53 7 40 2.3714860134327083 0.0177167172217305 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1533,2773,1916,95,2467,119,2162,2468,2400,55,20,105,2996,1209,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.053269504024264246,-0.9526617479367557,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +membrane traffic protein 22 63 2.364926653303836 0.0180336420547755 O95782,O00429,Q12907,A6NIH7,Q9H4M9,Q9HD42,Q13432,P43307,Q9H223,Q96FZ7,P50570,P78537,Q00765,Q8IUD2,Q9Y296,O00203,Q9Y2T2,Q9NX40,Q96RL7,Q8WUX9,Q9H269,Q96A65 Functions Panther Protein class panther_protein_class 627,505,631,15,546,283,31,36,567,566,559,680,682,357,485,472,503,373,497,639,642,388 15,472,505,1480,1958,748,1299,843,2059,627,1162,1773,2163,2069,1726,1170,36,2922,961,559,1781,2550,2859,2370,680,682,1875,2405,631,31,2288,357,1136,1227,1983,639,735,388,1846,980,566,2348,1185,497,3079,1144,567,642,1145,546,1192,2106,283,2491,373,1556,1151,1292,1152,1856,838,485,503 3.752502074253957,0.7920526088666452,0.7480967979523666,0.08107837999042887,-0.20938691832830006,0.5418751241716249,0.18979526604543842,0.4698445071041799,-0.2709736160130218,0.6352911062035237,0.26881271098746073,-0.08979570423491805,-0.3337570158659335,-0.2709736160130218,-0.0606293056858646,0.26881271098746073,2.8523931916992176,-1.1805061058028332,0.39603391908014063,0.7034844439548688,-0.08979570423491805,-0.6656250951850902,-1.065237448909853,-0.49595119132772597,0.5889482912953588,0.5889482912953588,-0.14899690656748693,-0.5292875863064875,0.6352911062035237,2.9809050828258044,-0.4301759669868179,0.9409952878769652,0.29469410743066005,0.2427051145911597,-0.20938691832830006,0.6352911062035237,0.5655044371788908,0.8991926986389834,-0.11924966294507812,0.39603391908014063,0.7034844439548688,-0.462913985518726,0.26881271098746073,0.7701555617414707,-1.7111232730375066,0.29469410743066005,0.7034844439548688,0.6352911062035237,0.29469410743066005,0.7258739119100094,0.26881271098746073,-0.2709736160130218,1.063003214209736,-0.5968579512594566,0.9201671263885668,0.053269504024264246,0.29469410743066005,0.21636733085825482,0.29469410743066005,-0.11924966294507812,0.4940482237889104,0.7920526088666452,0.7701555617414707 3193 +Lysosomal transport 17 39 2.3608743403678503 0.0182319072484906 P07602,O95295,O00203,Q9Y2T2,Q96FZ7,Q8IWJ2,O14964,Q99816,Q9UID3,O14617,Q8WUX9,Q14108,Q9HD42,O15118,Q9H269,Q9NZJ7,Q9UNK0 Processes and pathways GO Biological process msigdb_gobp 67,347,472,503,566,462,322,739,801,415,639,51,283,208,642,321,124 472,415,322,1480,208,1958,347,67,1255,1915,1162,1303,1773,1394,1629,1497,2982,51,2786,2809,462,639,1371,566,1185,739,1652,642,283,2458,321,1556,837,1151,801,1856,1294,124,503 0.7920526088666452,0.856796727704752,0.9822208710006587,0.08107837999042887,1.2182943630695027,-0.20938691832830006,0.9409952878769652,2.1802255667070183,0.21636733085825482,-0.1790423277350827,0.26881271098746073,0.18979526604543842,-0.08979570423491805,0.13593136335059053,-0.0031371136066703498,0.08107837999042887,-1.3383867666926692,2.391845426042903,-0.9526617479367557,-0.9898877670258749,0.813790292416791,0.6352911062035237,0.16298471623624555,0.7034844439548688,0.26881271098746073,0.5655044371788908,-0.0031371136066703498,0.6352911062035237,1.063003214209736,-0.5629231723307153,1.0026222188239642,0.053269504024264246,0.4940482237889104,0.29469410743066005,0.5180573956646057,-0.11924966294507812,0.21636733085825482,1.6409002994968682,0.7701555617414707 3193 +Asymmetric localization of pcp proteins 7 38 2.344267604417391 0.0190644872665659 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,2942,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,-1.2195274337089115,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Sterol binding 6 14 2.337624576587621 0.0194067318790616 Q14849,P30536,P45880,Q14108,O15118,P21796 Functions GO Molecular function msigdb_gomf 294,100,38,51,208,26 208,2729,2969,26,2318,2065,100,324,38,1131,51,294,1232,2767 1.2182943630695027,-0.8791073450641793,-1.2984677625692256,3.0940370861233606,-0.462913985518726,-0.2709736160130218,1.8007392900685555,0.9822208710006587,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121 3193 +Cellular transition metal ion homeostasis 12 21 2.330383727779973 0.0197858790294445 O00203,P09601,Q8N511,Q9H3K6,P21399,Q15904,O14617,Q9Y487,O60826,O75027,Q8TAD4,O76003 Processes and pathways GO Biological process msigdb_gobp 472,7,139,700,576,460,415,153,672,673,280,187 472,415,1766,672,673,2360,187,749,1720,7,576,2508,2959,2554,1504,460,139,280,1190,700,153 0.7920526088666452,0.856796727704752,-0.08979570423491805,0.5889482912953588,0.5889482912953588,-0.49595119132772597,1.3114045548408733,0.5418751241716249,-0.0606293056858646,4.132037847844936,0.680925878721421,-0.631091924935383,-1.258847985434175,-0.6656250951850902,0.08107837999042887,0.813790292416791,1.5576536448951719,1.063003214209736,0.26881271098746073,0.5889482912953588,1.5065684931882488 3193 +E2f mediated regulation of dna replication 8 12 2.329274182357477 0.0198445451897808 P49642,Q13416,Q9Y619,P06493,Q9UBD5,P14635,P09884,P06400 Processes and pathways Reactome Pathways msigdb_reactome 598,632,72,236,800,209,777,277 906,277,236,777,209,1536,1537,598,1311,632,800,72 0.42084065117869884,1.063003214209736,1.1416579910536835,0.5180573956646057,1.2182943630695027,0.053269504024264246,0.053269504024264246,0.6581956434453833,0.18979526604543842,0.6352911062035237,0.5180573956646057,2.166487793701175 3193 +Antigen processing cross presentation 15 52 2.3234426660633765 0.0201553843069313 P09429,P04439,P51665,P10321,Q14997,P49721,P28074,Q9UIQ6,O43242,P28072,P25787,Q03518,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 312,311,352,377,167,8,105,47,417,20,119,87,55,30,95 2463,525,2356,1907,2050,1993,989,417,2823,913,3020,311,312,377,1916,95,2467,119,2162,2468,2547,2400,55,20,105,2697,2996,2998,1261,1446,8,352,3068,2859,30,478,2074,1631,2434,2802,87,729,2707,1545,167,929,795,2143,47,1523,1295,1760 -0.5968579512594566,0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,-1.0274130001280428,0.42084065117869884,-1.459939156603208,1.0026222188239642,1.0026222188239642,0.8991926986389834,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.6656250951850902,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-0.8427789578797747,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.065237448909853,3.0017959971834336,0.7920526088666452,-0.2709736160130218,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.9818952092384208,0.5655044371788908,-0.8427789578797747,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,2.5046047789471104,0.08107837999042887,0.21636733085825482,-0.0606293056858646 3193 +Steroid metabolic process 18 67 2.3224893966601106 0.0202065987086348 O14734,P48449,Q14849,P30536,Q15392,Q15036,Q9UBM7,P35610,Q9UKR5,Q14739,Q8WTV0,Q13510,O15118,Q16850,Q9BQE5,P34913,P42765,P04062 Processes and pathways GO Biological process msigdb_gobp 251,99,294,100,70,367,141,324,143,175,18,50,208,93,27,190,61,158 251,208,1564,2729,574,3092,507,158,2991,1720,3166,1087,2397,2116,2507,2318,2065,3102,3164,752,100,190,324,1573,1091,3113,61,99,2165,2780,2167,1782,2511,1131,1686,2516,1874,50,1641,1320,175,294,367,1879,1834,70,1408,1739,1880,381,93,732,1740,1365,1329,18,3132,942,2764,27,2767,2350,141,1120,1425,143,3089 1.102589523776575,1.2182943630695027,0.025199324650836994,-0.8791073450641793,0.680925878721421,-1.7972452332773272,0.7480967979523666,1.4545942332074184,-1.3786049993712943,-0.0606293056858646,-2.823589938644955,0.3203531886001632,-0.5292875863064875,-0.30221572716540523,-0.631091924935383,-0.462913985518726,-0.2709736160130218,-1.8407550802597537,-2.7243005898102766,0.5418751241716249,1.8007392900685555,1.2930133010682965,0.9822208710006587,0.025199324650836994,0.3203531886001632,-1.928672515138034,2.2345531829313767,1.8317054739763257,-0.3337570158659335,-0.9526617479367557,-0.3337570158659335,-0.08979570423491805,-0.631091924935383,0.29469410743066005,-0.031744908526115174,-0.631091924935383,-0.14899690656748693,2.4045866103244666,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,0.9201671263885668,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,0.13593136335059053,-0.0606293056858646,-0.14899690656748693,0.8991926986389834,1.9077445032407137,0.5655044371788908,-0.0606293056858646,0.16298471623624555,0.18979526604543842,3.4188452578218076,-2.1080983881921154,0.42084065117869884,-0.9157349411807121,3.0940370861233606,-0.9157349411807121,-0.462913985518726,1.5576536448951719,0.3203531886001632,0.13593136335059053,1.5407221737348815,-1.7540346313524435 3193 +Signaling by the b cell receptor bcr 8 49 2.3184361661918453 0.0204256284174575 P49721,P28074,P28072,P25787,P28070,P62942,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,148,30,95 525,2356,1907,2050,1993,989,417,1159,913,1387,2114,2063,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,148,440,1266,756,729,3105,1545,1584,167,929,795,2143,1523,1295,1760 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.26881271098746073,0.42084065117869884,0.13593136335059053,-0.30221572716540523,-0.2709736160130218,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,1.5065684931882488,0.8353709145003145,0.21636733085825482,0.5418751241716249,0.5655044371788908,-1.8407550802597537,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.0606293056858646 3193 +Thin eyebrow 7 14 2.311092168734594 0.0208277644624532 P48449,P14923,P41227,Q9UM00,O75419,P15924,Q96EK5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 99,290,223,310,301,86,186 1157,301,3091,290,86,223,628,99,353,1828,1879,186,2305,310 0.26881271098746073,1.0228851550061475,-1.7972452332773272,1.0430115443451933,1.9818952092384208,1.1802219848882647,0.6352911062035237,1.8317054739763257,0.9409952878769652,-0.11924966294507812,-0.14899690656748693,1.3296832447901088,-0.4301759669868179,1.0228851550061475 3193 +Abc transporter disorders 8 41 2.305520029619876 0.0211374663012797 P49721,P28074,Q9UBV2,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,152,20,119,55,30,95 525,2356,1907,2050,1993,417,913,2729,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,2982,30,478,1631,2434,2802,729,1545,167,929,795,2143,297,152,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.8791073450641793,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,1.0430115443451933,1.5065684931882488,0.08107837999042887,0.21636733085825482 3193 +Defective cftr causes cystic fibrosis 8 41 2.305520029619876 0.0211374663012797 P49721,P28074,Q9UBV2,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,152,20,119,55,30,95 525,2356,1907,2050,1993,417,913,2729,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,2982,30,478,1631,2434,2802,729,1545,167,929,795,2143,297,152,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.8791073450641793,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,1.0430115443451933,1.5065684931882488,0.08107837999042887,0.21636733085825482 3193 +Protein insertion into membrane 11 26 2.300412818490553 0.0214248432937549 Q15629,O14737,Q15070,P46379,Q7L5D6,Q9P0J0,P30419,Q9NPA0,Q9P0I2,Q9NS69,Q8WWC4 Processes and pathways GO Biological process msigdb_gobp 130,252,326,75,343,249,361,644,646,24,587 252,624,1482,2728,915,361,2618,75,2074,2202,326,130,2628,1883,343,1696,587,826,644,24,646,249,1198,1476,2393,802 1.102589523776575,0.6352911062035237,0.08107837999042887,-0.8791073450641793,0.42084065117869884,0.9201671263885668,-0.7355890326334656,2.0968345345583104,-0.2709736160130218,-0.3655974840969154,0.9822208710006587,1.5912312904288737,-0.7355890326334656,-0.14899690656748693,0.9616792082789943,-0.031744908526115174,0.680925878721421,0.4940482237889104,0.6352911062035237,3.193291468873368,0.6352911062035237,1.1221876398575348,0.26881271098746073,0.10863077097339395,-0.49595119132772597,0.5180573956646057 3193 +Vacuole organization 22 54 2.30005536628235 0.0214450835175243 Q16706,Q8N511,Q7Z3C6,P04062,P42345,P62820,P53365,P50897,Q9UHD9,Q9P253,P10253,Q14108,O75503,Q9HC07,P54802,O95295,O00203,P50851,Q9H2M9,Q14457,Q9H269,P11117 Processes and pathways GO Biological process msigdb_gobp 789,139,278,158,530,532,164,37,704,837,303,51,184,469,339,347,472,721,768,493,642,125 472,1666,2823,184,2730,347,1346,158,1864,2645,303,125,1821,998,530,721,37,1629,164,339,1397,965,532,2405,51,493,818,1179,789,1365,278,935,139,1698,1935,1371,2411,2741,1185,1802,642,768,469,945,2458,837,704,1856,2391,1294,1808,1238,2820,1663 0.7920526088666452,-0.031744908526115174,-1.0274130001280428,1.3296832447901088,-0.8791073450641793,0.9409952878769652,0.16298471623624555,1.4545942332074184,-0.14899690656748693,-0.7710198034073763,1.0228851550061475,1.6244355839494933,-0.11924966294507812,0.3710194511388473,0.7258739119100094,0.5655044371788908,2.8414299150165303,-0.0031371136066703498,1.41943529737493,0.9616792082789943,0.13593136335059053,0.39603391908014063,0.7258739119100094,-0.5292875863064875,2.391845426042903,0.7701555617414707,0.4940482237889104,0.26881271098746073,0.5180573956646057,0.16298471623624555,1.063003214209736,0.42084065117869884,1.5576536448951719,-0.031744908526115174,-0.1790423277350827,0.16298471623624555,-0.5292875863064875,-0.8791073450641793,0.26881271098746073,-0.08979570423491805,0.6352911062035237,0.5418751241716249,0.813790292416791,0.42084065117869884,-0.5629231723307153,0.4940482237889104,0.5889482912953588,-0.11924966294507812,-0.49595119132772597,0.21636733085825482,-0.08979570423491805,0.2427051145911597,-0.9898877670258749,-0.0031371136066703498 3193 +Regulation of runx2 expression and activity 7 42 2.2983975774983154 0.0215391712705148 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,1493,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1266,729,1545,1639,1584,167,929,795,2143,1523,3089,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.08107837999042887,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,0.5655044371788908,0.053269504024264246,-0.0031371136066703498,0.025199324650836994,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,-1.7540346313524435,0.21636733085825482 3193 +Retinoblastoma gene in cancer 22 48 2.2968360198557964 0.0216281259211295 P09455,P00374,P35244,P33981,P09884,P06400,Q14566,P24941,O75419,P09429,Q9Y619,O14757,P14635,Q15054,P11802,P49642,Q14527,P33991,Q07864,P31350,P26583,P06493 Processes and pathways WikiPathways msigdb_wp 128,14,397,654,777,277,293,422,301,312,72,571,209,459,215,598,605,719,225,718,107,236 571,301,1252,877,14,2773,277,236,312,128,777,2733,215,2828,209,1163,1490,2005,422,781,847,107,1676,718,654,719,1038,397,2958,1678,2236,598,1130,1006,1634,225,1639,3120,605,293,2129,459,1588,2215,2456,1859,1903,72 0.680925878721421,1.0228851550061475,0.21636733085825482,0.44544306819693447,3.902465612713916,-0.9526617479367557,1.063003214209736,1.1416579910536835,1.0026222188239642,1.6078795867372875,0.5180573956646057,-0.8791073450641793,1.1993188415722877,-1.0274130001280428,1.2182943630695027,0.26881271098746073,0.08107837999042887,-0.24003068040751657,0.856796727704752,0.5180573956646057,0.4698445071041799,1.7536794627358119,-0.031744908526115174,0.5655044371788908,0.612209574085093,0.5655044371788908,0.34579373996602075,0.8780699365084367,-1.258847985434175,-0.031744908526115174,-0.3977371338220593,0.6581956434453833,0.29469410743066005,0.3710194511388473,-0.0031371136066703498,1.1802219848882647,-0.0031371136066703498,-1.9730801058799055,0.6581956434453833,1.0430115443451933,-0.30221572716540523,0.813790292416791,0.025199324650836994,-0.3655974840969154,-0.5629231723307153,-0.11924966294507812,-0.14899690656748693,2.166487793701175 3193 +Hedgehog on state 13 43 2.2965212536898227 0.0216460953571826 P51665,Q14997,P49721,Q9Y496,P61289,P28074,O43242,P28072,P48729,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 352,167,8,504,478,105,417,20,338,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,338,2431,1446,8,352,3068,30,478,1631,2434,2802,729,1545,1048,167,929,2177,2298,795,2143,1523,1295,504 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.9616792082789943,-0.5629231723307153,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,0.34579373996602075,1.41943529737493,0.42084065117869884,-0.3337570158659335,-0.4301759669868179,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,0.7701555617414707 3193 +Carboxylic acid binding 9 30 2.2952434837860736 0.0217191744696734 P09455,P07602,Q32P28,O15460,P13674,P00374,P34896,Q9NZJ7,P41440 Functions GO Molecular function msigdb_gomf 128,67,132,375,199,14,337,321,243 2421,2051,375,2113,451,14,1033,1085,67,128,960,1162,2777,199,2065,2319,1491,337,2938,243,578,629,2475,2242,1581,972,132,1284,2492,321 -0.5629231723307153,-0.2709736160130218,0.8991926986389834,-0.30221572716540523,0.813790292416791,3.902465612713916,0.34579373996602075,0.3203531886001632,2.1802255667070183,1.6078795867372875,0.39603391908014063,0.26881271098746073,-0.9526617479367557,1.2558874980500507,-0.2709736160130218,-0.462913985518726,0.08107837999042887,0.9616792082789943,-1.2195274337089115,1.1221876398575348,0.680925878721421,0.6352911062035237,-0.5968579512594566,-0.3977371338220593,0.025199324650836994,0.39603391908014063,1.574489660490009,0.21636733085825482,-0.5968579512594566,1.0026222188239642 3193 +Metabolism of vitamins and cofactors 12 44 2.2936967686368983 0.0218079224964782 P09455,P78417,P43490,P35270,Q9H2D1,O75874,P00374,Q99707,Q9NRN7,Q9HC21,P41440,Q13057 Processes and pathways Reactome Pathways msigdb_reactome 128,1,96,131,35,136,14,308,239,112,243,156 2051,549,136,2967,14,3092,1033,1671,915,128,2695,960,2734,2364,1967,1259,337,2938,131,243,96,1577,629,1,156,2862,1327,611,2913,1647,3124,1226,1933,1282,1284,308,35,112,2105,2872,239,568,2921,2580 -0.2709736160130218,0.7034844439548688,1.5576536448951719,-1.2984677625692256,3.902465612713916,-1.7972452332773272,0.34579373996602075,-0.031744908526115174,0.42084065117869884,1.6078795867372875,-0.8427789578797747,0.39603391908014063,-0.8791073450641793,-0.49595119132772597,-0.20938691832830006,0.21636733085825482,0.9616792082789943,-1.2195274337089115,1.574489660490009,1.1221876398575348,1.8775608468012885,0.025199324650836994,0.6352911062035237,5.401623940688195,1.4720196860623391,-1.065237448909853,0.18979526604543842,0.6581956434453833,-1.1417840001131578,-0.0031371136066703498,-2.0177869473716163,0.2427051145911597,-0.1790423277350827,0.21636733085825482,0.21636733085825482,1.0228851550061475,2.863316355216428,1.7058661157411827,-0.2709736160130218,-1.065237448909853,1.1416579910536835,0.7034844439548688,-1.1417840001131578,-0.6656250951850902 3193 +Rhizomelia 7 14 2.2846645412440414 0.022332505310894 Q03164,Q15392,Q9UBM7,Q14739,Q9BV10,Q8WTW3,O75718 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,70,141,175,115,245,394 1156,1031,2822,394,530,1094,68,175,1879,70,245,2528,115,141 0.26881271098746073,0.34579373996602075,-1.0274130001280428,0.8780699365084367,0.7258739119100094,0.3203531886001632,2.1802255667070183,1.3659083845750073,-0.14899690656748693,2.1802255667070183,1.1221876398575348,-0.631091924935383,1.6735598720423626,1.5576536448951719 3193 +Water soluble vitamin metabolic process 7 21 2.264734496795516 0.0235289772116209 P78417,Q9H2D1,Q9NRN7,P00374,Q99707,Q9HC21,P41440 Processes and pathways GO Biological process msigdb_gobp 1,35,239,14,308,112,243 14,2695,2364,2003,1259,337,2938,243,578,629,1,2340,1226,1282,2976,1284,308,35,112,239,3143 3.902465612713916,-0.8427789578797747,-0.49595119132772597,-0.24003068040751657,0.21636733085825482,0.9616792082789943,-1.2195274337089115,1.1221876398575348,0.680925878721421,0.6352911062035237,5.401623940688195,-0.462913985518726,0.2427051145911597,0.21636733085825482,-1.2984677625692256,0.21636733085825482,1.0228851550061475,2.863316355216428,1.7058661157411827,1.1416579910536835,-2.2458099647275738 3193 +Heterogeneous 16 40 2.2646799189008053 0.0235323286453101 O75844,Q16836,P35222,Q14126,P51798,Q9Y619,P53634,P00367,P50570,P07196,Q9NR77,P54098,P15924,P04792,Q9BQE5,P12235 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,295,720,427,291,72,724,575,559,551,52,85,86,185,27,527 991,129,1533,575,3020,914,2773,185,1720,2230,551,1162,527,86,1774,1675,848,720,2426,1574,2855,559,2780,291,724,85,1173,1131,427,758,1011,1880,295,1284,27,2105,52,1947,1811,72 0.3710194511388473,1.5912312904288737,0.053269504024264246,0.680925878721421,-1.459939156603208,0.42084065117869884,-0.9526617479367557,1.3296832447901088,-0.0606293056858646,-0.3977371338220593,0.7034844439548688,0.26881271098746073,0.7258739119100094,1.9818952092384208,-0.08979570423491805,-0.031744908526115174,0.4698445071041799,0.5655044371788908,-0.5629231723307153,0.025199324650836994,-1.065237448909853,0.7034844439548688,-0.9526617479367557,1.0430115443451933,0.5655044371788908,1.9965069209559112,0.26881271098746073,0.29469410743066005,0.856796727704752,0.5418751241716249,0.3710194511388473,-0.14899690656748693,1.0430115443451933,0.21636733085825482,3.0940370861233606,-0.2709736160130218,2.391845426042903,-0.1790423277350827,-0.08979570423491805,2.166487793701175 3193 +Abc family proteins mediated transport 9 51 2.2401042925532137 0.0250841529347527 P49721,P28074,Q9UBV2,P28072,P28070,P25787,P08183,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,152,20,55,119,147,30,95 525,2356,1907,2050,1993,417,673,913,2729,2000,147,1916,1089,95,2467,119,2162,2468,2400,55,20,105,752,1259,2996,1726,2998,1261,1446,8,352,3068,2982,2624,30,478,1631,2434,2802,729,1545,167,929,613,795,2143,297,2873,152,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.5889482912953588,0.42084065117869884,-0.8791073450641793,-0.24003068040751657,1.5065684931882488,-0.1790423277350827,0.3203531886001632,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.5418751241716249,0.21636733085825482,-1.3786049993712943,-0.0606293056858646,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,-1.3383867666926692,-0.7355890326334656,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.6581956434453833,0.5180573956646057,-0.30221572716540523,1.0430115443451933,-1.065237448909853,1.5065684931882488,0.08107837999042887,0.21636733085825482 3193 +Necrotic cell death 8 17 2.2389326725716385 0.0251602972199527 O00429,P30536,Q13546,Q13510,O15294,O60443,Q7Z3C6,P16989 Processes and pathways GO Biological process msigdb_gobp 505,100,265,50,174,54,278,313 505,174,54,959,2773,1085,527,313,2957,100,1577,50,265,278,1112,2253,1805 0.7480967979523666,1.3659083845750073,2.3403299146257823,0.39603391908014063,-0.9526617479367557,0.3203531886001632,0.7258739119100094,1.0026222188239642,-1.258847985434175,1.8007392900685555,0.025199324650836994,2.4045866103244666,1.0828619555333547,1.063003214209736,0.3203531886001632,-0.3977371338220593,-0.08979570423491805 3193 +Pcp ce pathway 7 47 2.236856169192776 0.0252957420417561 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,2059,627,2114,1086,1769,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,1731,3068,30,478,1631,2434,2802,2370,1635,729,1545,2942,167,929,1846,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,0.42084065117869884,-0.2709736160130218,0.6352911062035237,-0.30221572716540523,0.3203531886001632,-0.08979570423491805,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.0606293056858646,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.49595119132772597,-0.0031371136066703498,0.5655044371788908,0.053269504024264246,-1.2195274337089115,1.41943529737493,0.42084065117869884,-0.11924966294507812,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Steroid binding 8 19 2.229432312005525 0.025785154320904 Q14849,P30536,P45880,P35610,Q14108,O15118,P21796,P04062 Functions GO Molecular function msigdb_gomf 294,100,38,324,51,208,26,158 1526,208,435,2729,158,2991,2969,26,2318,2065,100,324,1091,38,1131,51,294,1232,2767 0.053269504024264246,1.2182943630695027,0.8353709145003145,-0.8791073450641793,1.4545942332074184,-1.3786049993712943,-1.2984677625692256,3.0940370861233606,-0.462913985518726,-0.2709736160130218,1.8007392900685555,0.9822208710006587,0.3203531886001632,2.7295242300793277,0.29469410743066005,2.391845426042903,1.0430115443451933,0.2427051145911597,-0.9157349411807121 3193 +Hypomimic face 7 13 2.22416143439726 0.0261375847467588 P35270,Q6P1N0,Q04637,P54098,Q96RR1,P12235,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 131,543,492,85,445,527,158 650,2540,158,527,131,85,492,1504,543,1794,1185,445,2306 0.612209574085093,-0.6656250951850902,1.4545942332074184,0.7258739119100094,1.574489660490009,1.9965069209559112,0.7701555617414707,0.08107837999042887,0.7258739119100094,-0.08979570423491805,0.26881271098746073,0.8353709145003145,-0.4301759669868179 3193 +Alcohol metabolic process 20 86 2.2237676136667672 0.0261640834388781 P35270,Q9UBM7,O75874,P00374,Q8WTV0,Q9BQE5,P04062,Q14849,Q14739,Q13510,P42765,P34913,Q15392,P35610,Q9BY49,O15118,P48735,Q16850,P48449,Q15036 Processes and pathways GO Biological process msigdb_gobp 131,141,136,14,18,27,158,294,175,50,61,190,70,324,345,208,90,93,99,367 2612,208,1668,1381,650,3008,2054,2056,1564,136,1670,2729,3117,14,3092,507,158,1720,3040,2543,1087,2777,2397,2003,2116,2507,2063,997,3102,2119,1823,190,131,324,1573,61,1727,99,90,2165,3025,2621,3086,2780,599,1782,2511,3147,655,1131,1686,1923,2516,2126,855,50,1641,1320,175,294,367,1879,1834,70,1880,381,3131,93,1836,1740,611,2249,2762,1933,18,2946,2985,27,1599,345,2188,1606,141,1120,2392,1990 -0.7355890326334656,1.2182943630695027,-0.031744908526115174,0.13593136335059053,0.612209574085093,-1.419122462160247,-0.2709736160130218,-0.2709736160130218,0.025199324650836994,1.5576536448951719,-0.031744908526115174,-0.8791073450641793,-1.9730801058799055,3.902465612713916,-1.7972452332773272,0.7480967979523666,1.4545942332074184,-0.0606293056858646,-1.5424702465695177,-0.6656250951850902,0.3203531886001632,-0.9526617479367557,-0.5292875863064875,-0.24003068040751657,-0.30221572716540523,-0.631091924935383,-0.2709736160130218,0.3710194511388473,-1.8407550802597537,-0.30221572716540523,-0.11924966294507812,1.2930133010682965,1.574489660490009,0.9822208710006587,0.025199324650836994,2.2345531829313767,-0.0606293056858646,1.8317054739763257,1.9227226839549494,-0.3337570158659335,-1.459939156603208,-0.7355890326334656,-1.7540346313524435,-0.9526617479367557,0.6581956434453833,-0.08979570423491805,-0.631091924935383,-2.339113975187537,0.612209574085093,0.29469410743066005,-0.031744908526115174,-0.1790423277350827,-0.631091924935383,-0.30221572716540523,0.4698445071041799,2.4045866103244666,-0.0031371136066703498,0.18979526604543842,1.3659083845750073,1.0430115443451933,0.9201671263885668,-0.14899690656748693,-0.11924966294507812,2.1802255667070183,-0.14899690656748693,0.8991926986389834,-2.062793041012379,1.9077445032407137,-0.11924966294507812,-0.0606293056858646,0.6581956434453833,-0.3977371338220593,-0.9157349411807121,-0.1790423277350827,3.4188452578218076,-1.2195274337089115,-1.3383867666926692,3.0940370861233606,0.025199324650836994,0.9616792082789943,-0.3337570158659335,0.025199324650836994,1.5576536448951719,0.3203531886001632,-0.49595119132772597,-0.20938691832830006 3193 +Corneal opacity 11 52 2.222991850070817 0.0262163495327221 O75844,O43505,Q9UBM7,P34913,P16278,O95202,Q06136,Q13510,P53701,P10619,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,39,141,190,263,262,16,50,363,60,158 1243,1157,989,39,473,2933,1669,2822,1083,129,1564,1251,262,1818,914,158,2501,996,777,60,263,2677,360,1772,190,2698,1726,2473,599,962,363,1682,2624,2330,2126,16,1132,2478,50,1052,2021,1505,759,2290,3006,1338,1900,141,2459,2391,2048,1760 0.21636733085825482,0.26881271098746073,0.3710194511388473,2.7180994529009332,0.7920526088666452,-1.2195274337089115,-0.031744908526115174,-1.0274130001280428,0.3203531886001632,1.5912312904288737,0.025199324650836994,0.21636733085825482,1.0828619555333547,-0.11924966294507812,0.42084065117869884,1.4545942332074184,-0.631091924935383,0.3710194511388473,0.5180573956646057,2.261350745716217,1.0828619555333547,-0.8067497779060742,0.9201671263885668,-0.08979570423491805,1.2930133010682965,-0.8427789578797747,-0.0606293056858646,-0.5968579512594566,0.6581956434453833,0.39603391908014063,0.9201671263885668,-0.031744908526115174,-0.7355890326334656,-0.462913985518726,-0.30221572716540523,3.703535835976282,0.29469410743066005,-0.5968579512594566,2.4045866103244666,0.34579373996602075,-0.24003068040751657,0.08107837999042887,0.5418751241716249,-0.4301759669868179,-1.3786049993712943,0.18979526604543842,-0.14899690656748693,1.5576536448951719,-0.5629231723307153,-0.49595119132772597,-0.24003068040751657,-0.0606293056858646 3193 +Endoplasmic reticulum 137 464 2.221964025280372 0.0262857368930586 Q9NR31,O00429,Q15437,P07099,P30519,P09601,O00767,P04035,P24390,Q9NX74,Q06136,Q9BQE5,Q9UMX5,P42345,Q9UQB8,P62820,P83881,P43307,Q9Y282,Q9H223,Q96G23,P80303,O43731,Q13510,Q14108,O95674,Q7L0J3,Q99720,P10619,Q02818,Q86UE4,Q15392,O95197,O95470,P00367,P21399,P27105,Q9H6V9,Q6NUM9,Q9BU23,Q03518,Q9BT22,Q16850,O60506,P48449,P30536,O00213,P51648,Q2TAA5,Q8TB61,Q96HY6,Q9BV10,Q9P0I2,Q5BJF2,Q9NPA0,Q12959,Q9UNK0,P46778,O43681,O75844,Q15629,Q32P28,Q02878,Q8N511,Q9UBM7,Q9BRR6,Q9UKR5,Q9Y680,Q9UBV2,Q9BRK5,P62942,P42858,O60725,P04062,Q16611,Q14739,O75503,Q16880,Q9NQC3,Q5VUD6,Q6NUQ1,P13674,Q9H3N1,O15118,O95487,Q9H488,Q13190,P06493,Q9H2J4,Q8IV08,Q9NZ08,Q96AY3,Q7Z3C6,Q9UL25,Q9BUN8,Q14849,P67812,O43852,O15498,Q9UM00,Q86YV9,P62847,P55327,Q9BTY2,Q96A57,P04439,Q8WVQ1,Q13641,P35610,P11047,P46776,Q15800,P10321,O15460,Q5VYK3,Q9P2W9,O75718,Q07065,Q14257,Q01105,Q9UBF8,O60476,P62266,O15173,Q9UBR2,Q15904,P48723,Q9HD20,Q9Y296,Q9Y244,Q96RL7,Q86XL3,Q14457,P50402,P48651,Q8TCT9,Q99735 Localization GO Cellular component msigdb_gocc 523,505,514,5,6,7,506,507,13,548,16,27,29,530,33,532,533,36,570,567,41,46,49,50,51,550,53,57,60,63,585,70,71,574,575,576,577,80,611,619,87,91,93,596,99,100,591,599,108,638,640,115,646,117,644,121,124,628,624,129,130,132,630,139,141,140,143,144,152,151,148,155,157,158,171,175,184,188,195,201,202,199,212,208,213,230,226,236,248,267,272,269,278,299,297,294,292,288,286,310,307,305,316,320,319,311,332,325,324,349,362,381,377,375,382,414,394,399,400,425,432,419,439,435,470,460,454,483,485,502,497,494,493,490,489,520,521 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3193 +Negative regulation of autophagy 9 21 2.220535676569427 0.0263824266857155 P42345,P30536,P09601,Q9NNW5,Q9NQ88,Q14457,Q04637,O15118,P10619 Processes and pathways GO Biological process msigdb_gobp 530,100,7,547,178,493,492,208,60 208,1382,2823,2773,2002,7,60,100,1040,530,786,1314,492,493,1935,2741,547,178,1947,1521,648 1.2182943630695027,0.13593136335059053,-1.0274130001280428,-0.9526617479367557,-0.24003068040751657,4.132037847844936,2.261350745716217,1.8007392900685555,0.34579373996602075,0.7258739119100094,0.5180573956646057,0.18979526604543842,0.7701555617414707,0.7701555617414707,-0.1790423277350827,-0.8791073450641793,0.7258739119100094,1.3659083845750073,-0.1790423277350827,0.08107837999042887,0.6352911062035237 3193 +Positive regulation of epithelial cell proliferation 6 20 2.219286867481295 0.0264672144735831 P09429,Q86VI3,Q9NQC3,P09601,P26583,Q9H2J4 Processes and pathways GO Biological process msigdb_gobp 312,296,195,7,107,248 1030,1563,1817,2853,312,7,349,2830,1771,107,720,1040,1356,2709,1739,2630,296,1649,248,195 0.34579373996602075,0.025199324650836994,-0.11924966294507812,-1.065237448909853,1.0026222188239642,4.132037847844936,0.9409952878769652,-1.0274130001280428,-0.08979570423491805,1.7536794627358119,0.5655044371788908,0.34579373996602075,0.16298471623624555,-0.8427789578797747,-0.0606293056858646,-0.7355890326334656,1.0430115443451933,-0.0031371136066703498,1.1221876398575348,1.2930133010682965 3193 +Cellular monovalent inorganic cation homeostasis 8 26 2.2188228571152444 0.0264987783505961 Q9Y6M7,P50897,O95295,Q8N511,Q9HC07,Q92544,Q9Y487,O75503 Processes and pathways GO Biological process msigdb_gobp 102,37,347,139,469,407,153,184 184,347,2991,2644,1962,2396,2234,1168,37,1629,1869,2369,1211,2554,1785,460,139,407,793,1371,469,1340,1710,153,987,102 1.3296832447901088,0.9409952878769652,-1.3786049993712943,-0.7710198034073763,-0.20938691832830006,-0.5292875863064875,-0.3977371338220593,0.26881271098746073,2.8414299150165303,-0.0031371136066703498,-0.14899690656748693,-0.49595119132772597,0.2427051145911597,-0.6656250951850902,-0.08979570423491805,0.813790292416791,1.5576536448951719,0.8780699365084367,0.5180573956646057,0.16298471623624555,0.813790292416791,0.18979526604543842,-0.031744908526115174,1.5065684931882488,0.39603391908014063,1.8007392900685555 3193 +Vacuolar transport 20 46 2.2145779112560886 0.026789049543479 Q9UID3,Q9HD42,Q96FZ7,O14617,Q9P253,Q14108,Q9NZJ7,P07602,Q8IWJ2,O14964,Q99816,O15118,O95295,O00203,Q9Y2T2,Q96RL7,Q8WUX9,Q14457,Q9H269,Q9UNK0 Processes and pathways GO Biological process msigdb_gobp 801,283,566,415,837,51,321,67,462,322,739,208,347,472,503,497,639,493,642,124 472,415,322,1480,208,1958,347,67,1255,1915,1162,1303,1773,1394,1629,1497,2982,2554,51,493,2786,2809,462,639,2345,1371,566,1185,497,1230,739,1652,642,1145,864,283,2458,321,1556,837,1151,801,1856,1294,124,503 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P62273,P61254,P08708,Q07020,P18077,P62081,Q9BXW9,P61313,P62847,P62899,P42766,P62244 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1004,755,916,813,1035,601,412,364,305,785,557,438 1435,916,1035,1539,557,2071,1353,1312,755,364,1044,601,438,1004,305,1828,785,1543,813,412,1617 0.10863077097339395,0.42084065117869884,0.34579373996602075,0.053269504024264246,0.7034844439548688,-0.2709736160130218,0.16298471623624555,0.18979526604543842,0.5418751241716249,0.9201671263885668,0.34579373996602075,0.6581956434453833,0.8353709145003145,0.3710194511388473,1.0228851550061475,-0.11924966294507812,0.5180573956646057,0.053269504024264246,0.4940482237889104,0.8780699365084367,0.025199324650836994 3193 +Dna replication 17 32 2.212811315734212 0.0269106568158066 P49642,P33991,Q07864,Q13416,Q9Y619,P24941,Q9UBD5,Q99741,O75419,P35244,Q15054,P35251,P41440,P09884,Q9Y2S7,Q7L590,Q14566 Processes and pathways WikiPathways msigdb_wp 598,719,225,632,72,422,800,697,301,397,459,555,243,777,648,216,293 906,301,777,2828,1163,422,781,1676,1258,719,1627,1038,397,2958,2698,555,1678,2236,243,2702,598,1311,1494,225,632,293,459,216,697,800,648,72 0.42084065117869884,1.0228851550061475,0.5180573956646057,-1.0274130001280428,0.26881271098746073,0.856796727704752,0.5180573956646057,-0.031744908526115174,0.21636733085825482,0.5655044371788908,-0.0031371136066703498,0.34579373996602075,0.8780699365084367,-1.258847985434175,-0.8427789578797747,0.7034844439548688,-0.031744908526115174,-0.3977371338220593,1.1221876398575348,-0.8427789578797747,0.6581956434453833,0.18979526604543842,0.08107837999042887,1.1802219848882647,0.6352911062035237,1.0430115443451933,0.813790292416791,1.1993188415722877,0.5889482912953588,0.5180573956646057,0.6352911062035237,2.166487793701175 3193 +G1 s dna damage checkpoints 7 42 2.207257241743365 0.0272960927048222 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,571,1993,417,913,1533,2773,1916,95,422,2467,119,2162,2468,2400,55,20,105,2996,1209,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,729,1545,167,929,795,2143,1523,1295 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,0.680925878721421,-0.24003068040751657,0.856796727704752,0.42084065117869884,0.053269504024264246,-0.9526617479367557,-0.1790423277350827,1.8775608468012885,0.856796727704752,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,0.2427051145911597,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482 3193 +Transition metal ion homeostasis 12 25 2.20423402366253 0.0275078901464673 O00203,P30519,P09601,Q8N511,Q9H3K6,P21399,Q15904,O14617,Q9Y487,O60826,Q8TAD4,O76003 Processes and pathways GO Biological process msigdb_gobp 472,6,7,139,700,576,460,415,153,672,280,187 472,415,1766,672,673,2360,187,749,2825,1720,7,576,6,2508,2959,2554,2128,1504,460,139,2961,280,1190,700,153 0.7920526088666452,0.856796727704752,-0.08979570423491805,0.5889482912953588,0.5889482912953588,-0.49595119132772597,1.3114045548408733,0.5418751241716249,-1.0274130001280428,-0.0606293056858646,4.132037847844936,0.680925878721421,4.195509236421808,-0.631091924935383,-1.258847985434175,-0.6656250951850902,-0.30221572716540523,0.08107837999042887,0.813790292416791,1.5576536448951719,-1.258847985434175,1.063003214209736,0.26881271098746073,0.5889482912953588,1.5065684931882488 3193 +Slc mediated transmembrane transport 9 21 2.2010281862385983 0.0277340285069325 Q9Y6M7,Q9H936,Q8TB61,Q99808,P53985,Q8TAD4,Q70HW3,Q9UBX3,P12235 Processes and pathways Reactome Pathways msigdb_reactome 102,78,638,664,82,280,88,259,527 1161,2061,2695,527,751,2508,1000,1039,82,1211,1504,1835,1643,88,280,638,664,1852,78,259,102 0.26881271098746073,-0.2709736160130218,-0.8427789578797747,0.7258739119100094,0.5418751241716249,-0.631091924935383,0.3710194511388473,0.34579373996602075,2.025517574520846,0.2427051145911597,0.08107837999042887,-0.11924966294507812,-0.0031371136066703498,1.9524555180193348,1.063003214209736,0.6352911062035237,0.612209574085093,-0.11924966294507812,2.068511822464931,1.102589523776575,1.8007392900685555 3193 +Sparse and thin eyebrow 6 12 2.199185157219552 0.0278647593021563 P48449,P14923,P41227,Q9UM00,P15924,Q96EK5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 99,290,223,310,86,186 1157,3091,290,86,223,628,99,353,1828,1879,186,310 0.26881271098746073,-1.7972452332773272,1.0430115443451933,1.9818952092384208,1.1802219848882647,0.6352911062035237,1.8317054739763257,0.9409952878769652,-0.11924966294507812,-0.14899690656748693,1.3296832447901088,1.0228851550061475 3193 +Proteasome complex 15 49 2.1980023440792618 0.0279489388951215 P51665,O43396,Q14997,P49721,Q5VYK3,P61289,P28074,Q8IWV7,O43242,P28072,P25787,P28070,P04792,P60900,P20618 Localization GO Cellular component msigdb_gocc 352,196,167,8,382,478,105,495,417,20,119,55,185,30,95 525,2356,1907,2050,1993,417,196,913,185,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,2653,1042,3068,2982,30,478,1631,2434,2802,1785,729,1545,167,929,1407,2082,382,495,795,2143,2900,1523,1295,2821 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.856796727704752,1.2745080889897082,0.42084065117869884,1.3296832447901088,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-0.7710198034073763,0.34579373996602075,-1.6685111568748416,-1.3383867666926692,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,-0.08979570423491805,0.5655044371788908,0.053269504024264246,1.41943529737493,0.42084065117869884,0.13593136335059053,-0.2709736160130218,0.8991926986389834,0.7701555617414707,0.5180573956646057,-0.30221572716540523,-1.103361115024735,0.08107837999042887,0.21636733085825482,-0.9898877670258749 3193 +Regulation of autophagy 24 89 2.196632086077132 0.0280467327556046 O75844,O00429,P09601,Q13137,Q9NNW5,Q9Y487,P42858,P21796,P12235,P04062,P19474,Q9NQ88,Q9NZJ7,P04792,P10619,P09429,P07602,Q9NZ45,Q96DM3,O15118,P30536,Q14457,Q04637,Q96A65 Processes and pathways GO Biological process msigdb_gobp 129,505,7,512,547,153,155,26,527,158,43,178,321,185,60,312,67,333,211,208,100,493,492,388 1619,1432,505,1122,2904,208,1668,1381,1382,1909,2823,843,129,1532,1346,158,1768,2773,185,1161,2231,67,2002,3033,312,7,60,527,43,1165,3009,2649,26,2234,100,1208,2959,1040,530,2012,155,1394,1129,2625,2554,3077,786,1314,1687,492,2783,512,687,1833,493,2806,818,1053,1222,585,2208,2719,2484,1698,1935,793,388,211,2741,1185,2946,1230,768,2187,547,178,1947,333,321,1521,1660,704,1710,1237,648,2820,153,872,1760 -0.0031371136066703498,0.10863077097339395,0.7480967979523666,0.29469410743066005,-1.1417840001131578,1.2182943630695027,-0.031744908526115174,0.13593136335059053,0.13593136335059053,-0.1790423277350827,-1.0274130001280428,0.4698445071041799,1.5912312904288737,0.053269504024264246,0.16298471623624555,1.4545942332074184,-0.08979570423491805,-0.9526617479367557,1.3296832447901088,0.26881271098746073,-0.3977371338220593,2.1802255667070183,-0.24003068040751657,-1.5010550842325505,1.0026222188239642,4.132037847844936,2.261350745716217,0.7258739119100094,2.6013806888194835,0.26881271098746073,-1.419122462160247,-0.7710198034073763,3.0940370861233606,-0.3977371338220593,1.8007392900685555,0.2427051145911597,-1.258847985434175,0.34579373996602075,0.7258739119100094,-0.24003068040751657,1.4720196860623391,0.13593136335059053,0.29469410743066005,-0.7355890326334656,-0.6656250951850902,-1.7111232730375066,0.5180573956646057,0.18979526604543842,-0.031744908526115174,0.7701555617414707,-0.9526617479367557,0.7480967979523666,0.5889482912953588,-0.11924966294507812,0.7701555617414707,-0.9898877670258749,0.4940482237889104,0.34579373996602075,0.2427051145911597,0.680925878721421,-0.3655974840969154,-0.8427789578797747,-0.5968579512594566,-0.031744908526115174,-0.1790423277350827,0.5180573956646057,0.8991926986389834,1.2182943630695027,-0.8791073450641793,0.26881271098746073,-1.2195274337089115,0.2427051145911597,0.5418751241716249,-0.3337570158659335,0.7258739119100094,1.3659083845750073,-0.1790423277350827,0.9822208710006587,1.0026222188239642,0.08107837999042887,-0.0031371136066703498,0.5889482912953588,-0.031744908526115174,0.2427051145911597,0.6352911062035237,-0.9898877670258749,1.5065684931882488,0.4698445071041799,-0.0606293056858646 3193 +Abnormality of the shoulder girdle musculature 12 32 2.1955895459433004 0.0281213351731155 O00429,P46976,P07602,P11047,Q14331,Q9Y487,P54098,Q96RR1,Q9Y5L0,Q9NZJ7,P50402,P12235 Drugs and Diseases Human Phenotype Ontology msigdb_hp 505,254,67,349,306,153,85,445,222,321,490,527 1992,505,1481,748,1563,2822,914,2230,551,67,349,527,2545,2237,254,490,85,2982,2739,1971,1268,306,1059,2295,445,1514,321,1424,153,222,1759,871 -0.24003068040751657,0.7480967979523666,0.08107837999042887,0.5418751241716249,0.025199324650836994,-1.0274130001280428,0.42084065117869884,-0.3977371338220593,0.7034844439548688,2.1802255667070183,0.9409952878769652,0.7258739119100094,-0.6656250951850902,-0.3977371338220593,1.102589523776575,0.7701555617414707,1.9965069209559112,-1.3383867666926692,-0.8791073450641793,-0.20938691832830006,0.21636733085825482,1.0228851550061475,0.34579373996602075,-0.4301759669868179,0.8353709145003145,0.08107837999042887,1.0026222188239642,0.13593136335059053,1.5065684931882488,1.1993188415722877,-0.0606293056858646,0.4698445071041799 3193 +Regulation of mrna stability by proteins that bind au rich elements 15 63 2.195175978943442 0.0281509766750054 P51665,Q14997,P49721,P28074,P61289,Q92973,O43242,Q04637,P28072,P20618,P25787,P28070,P04792,P60900,Q01105 Processes and pathways Reactome Pathways msigdb_reactome 352,167,8,105,478,370,417,492,20,95,119,55,185,30,425 525,2356,1907,2050,1993,1624,417,913,2312,185,1255,918,1916,95,2467,119,2162,2468,2400,55,20,105,1492,2401,2996,1777,2998,1261,1446,8,352,3068,30,478,1631,2434,2802,1499,425,492,2655,729,1545,1217,2172,167,929,2518,2520,635,2289,691,2212,370,3052,795,2143,2262,1420,1523,1295,953,1080 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,-0.0031371136066703498,0.856796727704752,0.42084065117869884,-0.462913985518726,1.3296832447901088,0.21636733085825482,0.42084065117869884,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,0.08107837999042887,-0.5292875863064875,-1.3786049993712943,-0.08979570423491805,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.08107837999042887,0.856796727704752,0.7701555617414707,-0.7710198034073763,0.5655044371788908,0.053269504024264246,0.2427051145911597,-0.3337570158659335,1.41943529737493,0.42084065117869884,-0.631091924935383,-0.631091924935383,0.6352911062035237,-0.4301759669868179,0.5889482912953588,-0.3655974840969154,0.9201671263885668,-1.5424702465695177,0.5180573956646057,-0.30221572716540523,-0.3977371338220593,0.13593136335059053,0.08107837999042887,0.21636733085825482,0.42084065117869884,0.34579373996602075 3193 +Golgi apparatus 63 166 2.193023231588843 0.0283057053330615 Q16706,O60499,P09601,Q9H2V7,Q96K12,Q93050,P53367,P24390,P16278,Q9BV57,Q9UID3,Q14CX7,Q9BRK5,Q9HB40,Q8TAD4,O00231,Q8NC54,P53365,P50897,P67812,Q8TDW0,Q9UBF8,Q96MW5,P80303,O60476,P50570,Q8IXU6,Q9NWM8,Q9UQ16,P55327,O95456,O60637,Q12893,P40818,Q02818,Q8N3C0,Q8IYS2,Q5VW38,O15260,P04439,Q8WVQ1,Q99996,Q6NUQ1,Q9HC07,Q8IWJ2,Q9NRZ9,Q5KU26,Q96A49,P18858,O00461,P50851,Q13190,O95295,O00203,Q8NCH0,Q969E2,P40616,Q9NUJ3,Q08378,Q8NE00,O15258,Q9HD45,Q8IZA0 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 789,376,7,271,270,793,137,13,263,411,801,788,151,22,280,525,692,164,37,292,824,432,828,46,419,559,48,836,838,316,805,58,581,314,63,586,193,65,804,311,332,465,202,469,462,743,342,616,716,98,721,226,347,472,234,110,488,645,757,387,746,258,385 1813,1906,1431,472,525,98,2747,2158,1480,1244,990,746,804,991,1957,3008,1765,1296,419,2727,376,58,1299,2879,2359,2822,1862,2309,347,805,1533,311,1720,2826,7,2193,1162,2365,263,716,2318,13,1675,1822,1205,2678,2698,920,1039,488,314,2922,1576,1094,1495,559,721,37,3086,1130,164,137,2368,1783,316,1043,292,46,1922,3026,1450,63,757,814,1875,581,226,2687,1833,3045,1405,788,1504,789,2629,342,2022,2337,65,2658,1365,202,1884,1366,1181,2983,1840,2338,974,935,462,1981,48,1593,2339,193,385,586,892,2091,692,234,387,280,1982,1059,2601,824,332,1699,1278,1113,793,110,616,270,828,895,1286,2573,465,3175,151,2790,411,1802,271,2350,2742,2301,1946,1020,2187,2104,2769,22,469,2106,258,2490,743,2219,645,2610,836,2149,432,2817,1855,801,1293,3060,838,2903,1618,904 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3193 +Apoptosis 18 119 2.192656788235967 0.0283321162900396 O14737,Q03164,O95197,P09601,Q9UHX1,P46379,P42858,Q16611,Q13546,P06493,Q9NQ88,O15294,Q9P0J0,Q96A26,Q9H2J4,P52756,Q9UDX5,P21796 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 252,68,71,7,135,75,155,171,265,236,178,174,249,181,248,304,89,26 591,3115,1241,2582,252,174,1909,473,2358,748,1669,1563,913,2394,2730,71,574,1346,713,1387,1533,1768,2773,1720,2114,236,7,751,1165,1352,26,1304,2234,1168,2957,879,529,2012,155,75,852,1041,2682,1781,304,478,1448,2513,2910,1687,561,68,1831,2127,2437,1502,2078,685,687,265,2479,2864,493,1321,1102,2081,1103,635,171,1456,1883,2087,1743,1884,1411,1981,2444,2294,1983,2094,2211,2603,1649,2032,181,1283,2604,2605,2298,2486,2034,2098,2144,1895,834,1801,1803,248,1114,1377,1602,178,2490,1117,1947,2043,321,249,89,2669,770,135,3054,2153,1859,985,2820,1475,2461 0.6581956434453833,-1.9730801058799055,0.21636733085825482,-0.7004574638193659,1.102589523776575,1.3659083845750073,-0.1790423277350827,0.7920526088666452,-0.49595119132772597,0.5418751241716249,-0.031744908526115174,0.025199324650836994,0.42084065117869884,-0.5292875863064875,-0.8791073450641793,2.166487793701175,0.680925878721421,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.053269504024264246,-0.08979570423491805,-0.9526617479367557,-0.0606293056858646,-0.30221572716540523,1.1416579910536835,4.132037847844936,0.5418751241716249,0.26881271098746073,0.16298471623624555,3.0940370861233606,0.18979526604543842,-0.3977371338220593,0.26881271098746073,-1.258847985434175,0.44544306819693447,0.7258739119100094,-0.24003068040751657,1.4720196860623391,2.0968345345583104,0.4698445071041799,0.34579373996602075,-0.8067497779060742,-0.08979570423491805,1.0228851550061475,0.7920526088666452,0.10863077097339395,-0.631091924935383,-1.1417840001131578,-0.031744908526115174,0.7034844439548688,2.1802255667070183,-0.11924966294507812,-0.30221572716540523,-0.5629231723307153,0.08107837999042887,-0.2709736160130218,0.5889482912953588,0.5889482912953588,1.0828619555333547,-0.5968579512594566,-1.065237448909853,0.7701555617414707,0.18979526604543842,0.3203531886001632,-0.2709736160130218,0.3203531886001632,0.6352911062035237,1.383857498630824,0.10863077097339395,-0.14899690656748693,-0.2709736160130218,-0.0606293056858646,-0.14899690656748693,0.13593136335059053,-0.20938691832830006,-0.5629231723307153,-0.4301759669868179,-0.20938691832830006,-0.2709736160130218,-0.3655974840969154,-0.7004574638193659,-0.0031371136066703498,-0.24003068040751657,1.3478507399601813,0.21636733085825482,-0.7004574638193659,-0.7004574638193659,-0.4301759669868179,-0.5968579512594566,-0.24003068040751657,-0.2709736160130218,-0.30221572716540523,-0.14899690656748693,0.4940482237889104,-0.08979570423491805,-0.08979570423491805,1.1221876398575348,0.3203531886001632,0.16298471623624555,0.025199324650836994,1.3659083845750073,-0.5968579512594566,0.3203531886001632,-0.1790423277350827,-0.24003068040751657,1.0026222188239642,1.1221876398575348,1.9524555180193348,-0.7710198034073763,0.5418751241716249,1.574489660490009,-1.5424702465695177,-0.30221572716540523,-0.11924966294507812,0.39603391908014063,-0.9898877670258749,0.10863077097339395,-0.5629231723307153 3193 +Protein targeting 26 114 2.188564874144636 0.0286284812072064 Q15629,O14737,Q16543,Q8N4H5,O60830,Q9NS69,O95429,O60725,Q99595,P43307,O14925,O14617,Q14108,P57105,P46379,Q8IWJ2,Q15388,O14964,Q7L5D6,Q5JRX3,P30536,P55786,O00203,Q9Y2T2,Q9P0J0,Q9GZY8 Processes and pathways GO Biological process msigdb_gobp 130,252,266,142,17,24,395,157,32,36,169,415,51,317,75,462,205,322,343,84,100,101,472,503,249,247 2581,1619,1430,472,415,252,572,169,322,1909,711,624,1482,157,17,1083,3084,1300,2728,2730,2642,395,1346,713,1388,915,2001,2675,3041,1255,1303,1165,1773,577,2321,3034,100,2880,529,1492,2618,2402,1726,36,75,1394,961,1210,1129,1629,1781,101,2624,317,2859,1097,2197,2074,2198,1045,1543,1499,1213,1687,855,2438,51,1738,205,130,1788,266,2560,2628,84,2630,343,2206,2809,1460,3049,462,142,2811,497,3106,1650,738,1230,32,831,247,864,2668,1608,24,945,249,1521,2743,867,1613,1340,984,3126,868,1294,503,2820,2355,1476,2393,802,1812 -0.7004574638193659,-0.0031371136066703498,0.10863077097339395,0.7920526088666452,0.856796727704752,1.102589523776575,0.680925878721421,1.383857498630824,0.9822208710006587,-0.1790423277350827,0.5655044371788908,0.6352911062035237,0.08107837999042887,1.4545942332074184,3.6453743945093926,0.3203531886001632,-1.7540346313524435,0.18979526604543842,-0.8791073450641793,-0.8791073450641793,-0.7710198034073763,0.8780699365084367,0.16298471623624555,0.5655044371788908,0.13593136335059053,0.42084065117869884,-0.24003068040751657,-0.8067497779060742,-1.5424702465695177,0.21636733085825482,0.18979526604543842,0.26881271098746073,-0.08979570423491805,0.680925878721421,-0.462913985518726,-1.5010550842325505,1.8007392900685555,-1.103361115024735,0.7258739119100094,0.08107837999042887,-0.7355890326334656,-0.5292875863064875,-0.0606293056858646,2.8523931916992176,2.0968345345583104,0.13593136335059053,0.39603391908014063,0.2427051145911597,0.29469410743066005,-0.0031371136066703498,-0.08979570423491805,1.8007392900685555,-0.7355890326334656,1.0026222188239642,-1.065237448909853,0.3203531886001632,-0.3655974840969154,-0.2709736160130218,-0.3655974840969154,0.34579373996602075,0.053269504024264246,0.08107837999042887,0.2427051145911597,-0.031744908526115174,0.4698445071041799,-0.5629231723307153,2.391845426042903,-0.0606293056858646,1.2371500809699392,1.5912312904288737,-0.08979570423491805,1.0828619555333547,-0.6656250951850902,-0.7355890326334656,2.0110474795908226,-0.7355890326334656,0.9616792082789943,-0.3655974840969154,-0.9898877670258749,0.10863077097339395,-1.5424702465695177,0.813790292416791,1.5407221737348815,-0.9898877670258749,0.7701555617414707,-1.8407550802597537,-0.0031371136066703498,0.5655044371788908,0.2427051145911597,2.9598669449402526,0.4940482237889104,1.1221876398575348,0.4698445071041799,-0.7710198034073763,0.025199324650836994,3.193291468873368,0.42084065117869884,1.1221876398575348,0.08107837999042887,-0.8791073450641793,0.4698445071041799,0.025199324650836994,0.18979526604543842,0.39603391908014063,-2.0177869473716163,0.4698445071041799,0.21636733085825482,0.7701555617414707,-0.9898877670258749,-0.462913985518726,0.10863077097339395,-0.49595119132772597,0.5180573956646057,-0.08979570423491805 3193 +Arthritis 12 40 2.1861274051082837 0.0288062855088839 O75844,Q9H488,P10321,Q8WVQ1,P51798,Q9NZ08,Q14739,Q13510,Q14108,P14174,P28070,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,230,377,332,291,272,175,50,51,242,55,158 1430,375,911,129,1534,3020,914,158,996,2315,377,2734,242,2677,1774,2735,55,1577,721,291,1783,1870,2801,2738,2074,2126,50,51,175,2376,820,332,2185,640,497,230,1751,272,2949,1525 0.10863077097339395,0.8991926986389834,0.42084065117869884,1.5912312904288737,0.053269504024264246,-1.459939156603208,0.42084065117869884,1.4545942332074184,0.3710194511388473,-0.462913985518726,0.8991926986389834,-0.8791073450641793,1.1221876398575348,-0.8067497779060742,-0.08979570423491805,-0.8791073450641793,2.301101464563815,0.025199324650836994,0.5655044371788908,1.0430115443451933,-0.08979570423491805,-0.14899690656748693,-0.9898877670258749,-0.8791073450641793,-0.2709736160130218,-0.30221572716540523,2.4045866103244666,2.391845426042903,1.3659083845750073,-0.49595119132772597,0.4940482237889104,0.9822208710006587,-0.3337570158659335,0.6352911062035237,0.7701555617414707,1.1802219848882647,-0.0606293056858646,1.0828619555333547,-1.2195274337089115,0.08107837999042887 3193 +Regulation of pten stability and activity 7 42 2.1845643603691696 0.0289208034695029 P49721,P28074,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 8,105,20,119,55,30,95 525,2356,1907,2050,1993,417,913,1916,1165,95,2467,119,2162,2468,2400,55,20,105,529,2996,2998,1394,1261,1446,8,352,3068,30,478,1631,2434,2802,1500,729,1545,167,929,795,2143,1523,3089,1295 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Localization GO Cellular component msigdb_gocc 67,377,6,354,9,420,302,303,280,86,321,399,220 2463,1526,594,804,1716,420,2308,2540,451,2059,302,3020,67,303,377,1915,1162,1303,86,1351,577,6,2508,1392,1000,2276,9,923,1495,1396,1629,1497,2368,1871,1784,965,2513,2626,399,2706,1360,1216,1318,2711,2019,932,354,1365,2524,2093,280,1461,793,1280,2919,1144,2768,1605,220,321,2691,839 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3193 +Endosomal transport 40 71 2.181182712728014 0.029169904943737 Q15057,O60499,P53367,Q9UID3,Q9C0C9,Q9H4M9,Q9HD42,Q4KMP7,O60493,O60749,Q4J6C6,O60271,Q9H223,Q96FZ7,O15498,O60784,O14617,P78537,O60826,O75503,Q96D71,O15260,Q4V328,Q8IWJ2,Q15904,O14964,P49257,Q9Y5X3,P61106,Q8IUD2,O75436,O00203,Q13190,Q15036,Q9Y5X1,P40616,Q8WUX9,Q9P2D3,Q9H269,Q14203 Processes and pathways GO Biological process msigdb_gobp 380,376,137,801,1067,546,283,541,774,274,1055,907,567,566,286,420,415,680,672,184,980,804,688,462,460,322,961,872,965,357,843,472,226,367,1029,488,639,250,642,758 472,415,322,804,286,907,774,376,274,420,672,843,184,1386,488,1170,961,1629,2737,137,2982,2625,1784,965,1398,680,1635,226,2128,2374,2942,758,367,380,1322,1179,460,1054,1055,541,688,1365,2809,357,462,639,1699,2345,1892,980,566,1185,2349,1067,567,642,1145,546,283,2458,1556,250,1151,1292,1660,801,3074,1294,1237,1029,872 0.7920526088666452,0.856796727704752,0.9822208710006587,0.4940482237889104,1.0430115443451933,0.42084065117869884,0.5180573956646057,0.8991926986389834,1.063003214209736,0.856796727704752,0.5889482912953588,0.4698445071041799,1.3296832447901088,0.13593136335059053,0.7701555617414707,0.26881271098746073,0.39603391908014063,-0.0031371136066703498,-0.8791073450641793,1.5576536448951719,-1.3383867666926692,-0.7355890326334656,-0.08979570423491805,0.39603391908014063,0.13593136335059053,0.5889482912953588,-0.0031371136066703498,1.1802219848882647,-0.30221572716540523,-0.49595119132772597,-1.2195274337089115,0.5418751241716249,0.9201671263885668,0.8991926986389834,0.18979526604543842,0.26881271098746073,0.813790292416791,0.34579373996602075,0.34579373996602075,0.7258739119100094,0.5889482912953588,0.16298471623624555,-0.9898877670258749,0.9409952878769652,0.813790292416791,0.6352911062035237,-0.031744908526115174,-0.462913985518726,-0.14899690656748693,0.39603391908014063,0.7034844439548688,0.26881271098746073,-0.462913985518726,0.34579373996602075,0.7034844439548688,0.6352911062035237,0.29469410743066005,0.7258739119100094,1.063003214209736,-0.5629231723307153,0.053269504024264246,1.1221876398575348,0.29469410743066005,0.21636733085825482,-0.0031371136066703498,0.5180573956646057,-1.6685111568748416,0.21636733085825482,0.2427051145911597,0.3710194511388473,0.4698445071041799 3193 +Interleukin 1 signaling 13 47 2.181049497583952 0.0291797556225108 P09429,P51665,Q14997,P49721,P28074,P61289,O43242,P61088,P28072,P25787,P28070,P60900,P20618 Processes and pathways Reactome Pathways msigdb_reactome 312,352,167,8,105,478,417,455,20,119,55,30,95 525,2356,1907,2050,1993,989,417,913,1720,312,1916,95,2467,119,2162,2468,2400,55,20,105,2996,2998,1261,1446,8,352,3068,30,455,478,1631,2434,2802,1266,2200,756,729,1545,1584,167,929,3037,795,2143,1523,1295,1760 0.7258739119100094,-0.49595119132772597,-0.1790423277350827,-0.2709736160130218,-0.24003068040751657,0.3710194511388473,0.856796727704752,0.42084065117869884,-0.0606293056858646,1.0026222188239642,-0.1790423277350827,1.8775608468012885,-0.5968579512594566,1.6409002994968682,-0.3337570158659335,-0.5968579512594566,-0.5292875863064875,2.301101464563815,3.308198222205599,1.7694486191853893,-1.3786049993712943,-1.3786049993712943,0.21636733085825482,0.10863077097339395,4.132037847844936,0.9409952878769652,-1.6685111568748416,3.0017959971834336,0.813790292416791,0.7920526088666452,-0.0031371136066703498,-0.5629231723307153,-0.9898877670258749,0.21636733085825482,-0.3655974840969154,0.5418751241716249,0.5655044371788908,0.053269504024264246,0.025199324650836994,1.41943529737493,0.42084065117869884,-1.5010550842325505,0.5180573956646057,-0.30221572716540523,0.08107837999042887,0.21636733085825482,-0.0606293056858646 3193