term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Organelle subcompartment 131 380 6.536856817946362 6.282514067830412e-11 Q6IAN0,P30519,Q15392,P24390,P01889,Q9P035,Q9BQE5,P09601,P07099,Q6NTF9,Q14108,O00461,Q99720,Q8NAT1,Q5VYK3,P43307,Q5BJF2,Q8N511,P67812,Q16706,Q9UM00,Q9UL01,Q8TB61,O95197,Q14849,Q96GC9,Q8NF37,Q9NPR9,O43731,O95487,Q96G23,Q6YHU6,O95470,P04062,Q86UE4,P51648,O75844,Q9Y282,Q03518,Q06136,Q15629,Q15800,Q9P2W9,P37268,Q9NQC3,Q9Y3B3,Q9HD20,Q9BRR6,Q86XL3,O60725,Q16850,P38435,Q8N0U8,P52292,O15127,O76062,O43292,Q9Y5M8,P48449,Q86YN1,Q5T9L3,Q8NFQ8,Q03519,A1L0T0,Q53GQ0,Q96KC8,P53367,Q8N5M9,Q8NBN3,Q9UBU6,Q9BUN8,O00264,Q96PC5,P05067,O14678,O60512,Q96L58,Q9NUQ2,Q15363,P27544,P16615,Q07065,O95249,Q9Y4P3,Q9H4A6,Q14534,Q8IV08,Q8TCT9,Q9BUR5,Q96HY6,Q8TBA6,Q15382,Q96RL7,Q9Y6B6,Q13190,P16435,Q14739,P49755,Q96A33,Q10472,O15260,Q658Y4,P42345,Q07812,Q9BT22,Q6NUM9,Q9NZ08,P51571,P35613,O95864,Q2TAA5,Q8NHH9,Q9H3N1,Q15041,Q9BVK6,Q15904,Q9UBM7,P48651,Q96N66,Q6UX53,O15269,Q969V3,Q7Z3C6,O76024,Q9BTU6,O75845,P57088,Q12907,P50570,O00767,Q9NPA0 Localization GO Cellular component msigdb_gocc 514,1,2,4,507,531,15,17,18,541,22,23,24,544,540,28,31,32,35,554,558,557,39,42,43,569,568,58,59,561,61,586,64,68,70,79,81,85,86,87,89,101,107,123,127,133,137,139,140,141,146,145,151,156,163,164,177,180,184,185,192,193,198,195,202,208,209,210,212,215,214,216,221,224,222,231,234,235,241,239,249,256,258,269,268,272,273,274,275,281,286,290,292,300,301,310,311,315,323,320,319,338,354,368,371,380,386,376,375,388,403,416,418,424,427,434,438,431,451,450,441,461,459,455,480,468,493,495,491,484,519 1241,195,812,216,1367,814,23,2818,815,484,2739,1202,1275,2740,222,867,1088,2044,678,2158,163,319,441,1673,1019,3070,177,59,1465,1618,729,702,1277,1833,231,1204,141,1998,1784,1736,1674,785,1785,624,81,468,817,455,164,2103,1787,869,2977,2292,2781,42,258,1889,2621,64,1208,561,1788,388,1738,1677,507,68,684,1627,1281,224,577,18,2209,2346,3217,3151,17,2049,1210,2210,3182,310,249,2747,2909,1567,3219,1248,2109,4,2629,239,3395,705,3298,2711,3334,1,3076,1570,1842,1341,985,375,123,145,2398,1748,354,28,2505,598,1250,184,431,873,874,2453,315,600,491,3153,376,1376,79,1174,156,209,2114,1029,2673,2716,2632,493,2060,3356,1799,1845,2871,2797,706,789,1346,948,2798,2012,2633,1641,2982,1689,1529,35,1752,1380,1531,1576,649,2551,1963,86,198,1533,1691,87,256,368,3025,1430,821,320,2013,1298,3098,495,1964,301,879,1138,1802,1487,22,2559,3185,768,272,311,605,43,3133,688,3282,424,710,2724,1064,241,290,2,990,89,1259,101,434,554,146,403,1652,202,31,1702,1703,192,2023,1032,540,3339,338,3274,514,541,380,653,1654,1914,3187,773,450,586,883,459,70,2067,140,1541,185,273,2365,3383,1442,151,852,1443,1394,32,2184,210,2242,1658,544,212,568,193,416,1588,2644,39,286,912,1112,2993,274,2690,2132,2604,2071,1447,1661,3140,588,2074,2188,461,323,718,1188,61,569,2997,281,208,234,1036,451,3176,2764,221,292,3244,1038,1113,633,2767,24,744,1316,2323,1502,15,1401,139,2733,2524,371,480,673,214,275,1770,3403,427,1504,2139,746,3210,3065,1457,1598,3289,1150,1268,1009,418,834,268,3358,2325,695,137,1871,2086,519,58,127,861,2967,2331,890,235,1010,1041,676,386,531,1195,1876,1877,2897,107,1360,438,215,1118,1509,1119,1934,1462,557,2039,558,1121,1510,1511,2700,969,85,1827,973,638,1082,133,2381,269,180,2384,811,1777,300,1778 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3430 Endoplasmic reticulum 190 488 6.3524476015768 2.1191562264243336e-10 P80303,P30519,Q15392,Q6IAN0,P24390,P01889,Q9P035,P30536,Q9BQE5,Q13641,P09601,P07099,Q6NTF9,Q14108,Q99720,Q8NAT1,Q5VYK3,P43307,Q5BJF2,Q8N511,P67812,Q02818,Q9UM00,Q9UL01,Q8TB61,O95197,Q14849,O76094,Q96GC9,Q8NF37,O43731,O95487,Q96G23,Q6YHU6,O95470,Q92643,P27635,P04062,Q86UE4,P06493,P51648,O75844,Q9Y282,Q03518,Q06136,Q8TED1,Q15629,Q92530,Q9UQB8,Q9Y680,O15118,O94832,Q15800,P46977,P50402,Q9P2W9,P50851,Q02878,Q99523,Q8TBX8,P10619,O75503,O15173,Q9Y394,P37268,O60476,Q9NQC3,Q9Y3B3,Q8IY95,Q6NUQ1,Q9HD20,Q9BRR6,Q86XL3,O60725,P46778,P26373,Q16850,P38435,P13674,O95302,Q9BU23,Q8N0U8,Q9NZ01,P52292,Q9BRK5,Q13510,P62820,O76062,Q9HCU5,O95456,O43292,Q15005,Q9Y5M8,P48449,Q86YN1,O14975,P04439,P14859,Q92542,Q5T9L3,Q8NFQ8,Q96AG4,Q03519,Q15631,A1L0T0,Q53GQ0,Q15042,O43865,Q96KC8,O00584,Q8N5M9,P27824,Q9UBU6,Q9BUN8,O00264,Q96PC5,P05067,O14678,Q14257,Q9NUQ2,P52789,P62847,Q15363,P27544,Q9NR31,P16615,Q96LJ7,Q07065,P42858,Q9Y4P3,Q14534,Q8IV08,Q8TCT9,Q9BUR5,Q96HY6,P55327,Q15382,Q96RL7,Q9Y6B6,Q13190,Q9H223,P16435,Q14739,P49755,Q96A33,Q9NWM8,Q10472,O15260,Q9UMX5,O95881,P42345,Q9BTY2,Q96AY3,Q07812,Q9BT22,Q99797,Q6NUM9,Q9NZ08,P51571,P35613,P15289,O95864,Q9H9S5,Q2TAA5,Q8NHH9,Q9H3N1,Q15041,Q9BVK6,Q15904,Q9UBM7,P48651,O43681,P83731,Q96N66,Q6UX53,O15269,Q969V3,Q7Z3C6,P62266,O76024,Q6ZXV5,Q01105,O75845,P57088,Q12907,O00767,P29692,Q9NPA0,Q9H6S0,Q9BTV4 Localization GO Cellular component msigdb_gocc 0,1,2,514,4,507,531,12,15,526,17,18,541,22,24,544,540,28,31,32,35,36,558,557,39,42,43,550,569,568,59,561,61,586,64,588,578,68,70,577,79,81,85,86,87,612,89,614,93,95,98,594,101,598,600,107,601,602,633,112,113,116,117,638,123,621,127,133,654,653,137,139,140,141,645,643,146,145,641,147,673,151,676,156,160,158,664,164,695,683,177,688,180,184,185,678,684,190,717,192,193,718,198,712,195,202,710,702,208,699,210,705,215,214,216,221,224,222,233,235,236,238,241,239,248,249,251,256,259,269,272,273,274,275,281,288,290,292,300,301,313,310,311,315,323,325,320,319,328,348,354,361,366,368,371,384,380,386,376,375,374,388,411,403,416,418,424,427,434,438,431,428,448,451,450,441,461,459,457,455,477,473,468,493,495,484,489,519,518,517 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3430 Nuclear outer membrane endoplasmic reticulum membrane network 115 314 5.873080857635064 4.277696940833311e-09 Q6IAN0,P30519,Q15392,P24390,P01889,Q9P035,Q9BQE5,P09601,P07099,Q6NTF9,Q14108,Q99720,Q8NAT1,P43307,Q5BJF2,Q8N511,P67812,Q9UM00,Q9UL01,Q8TB61,O95197,Q14849,Q96GC9,Q8NF37,O43731,O95487,Q96G23,Q6YHU6,O95470,Q86UE4,P51648,O75844,Q9Y282,Q03518,Q06136,Q15629,Q15800,Q9P2W9,P37268,Q9NQC3,Q9Y3B3,Q9HD20,Q9BRR6,Q86XL3,O60725,Q16850,P38435,Q8N0U8,P52292,O76062,O43292,Q9Y5M8,P48449,Q86YN1,Q5T9L3,Q8NFQ8,Q03519,A1L0T0,Q53GQ0,Q96KC8,Q8N5M9,Q9UBU6,Q9BUN8,O00264,Q96PC5,O14678,Q9NUQ2,Q15363,P27544,P16615,Q07065,Q9Y4P3,Q14534,Q8IV08,Q8TCT9,Q9BUR5,Q96HY6,Q15382,Q96RL7,Q9Y6B6,Q13190,P16435,Q14739,P49755,Q96A33,Q10472,O15260,P42345,Q07812,Q9BT22,Q6NUM9,Q9NZ08,P51571,P35613,O95864,Q2TAA5,Q8NHH9,Q9H3N1,Q15041,Q9BVK6,Q15904,Q9UBM7,P48651,Q96N66,Q6UX53,O15269,Q969V3,Q7Z3C6,O76024,O75845,P61970,P57088,Q12907,O00767,Q9NPA0 Localization GO Cellular component msigdb_gocc 514,1,2,4,507,531,15,17,18,541,22,24,544,28,31,32,35,558,557,39,42,43,569,568,59,561,61,586,64,70,79,81,85,86,87,89,101,107,123,127,133,137,139,140,141,146,145,151,156,164,177,180,184,185,192,193,198,195,202,208,210,215,214,216,221,222,235,241,239,249,256,269,272,273,274,275,281,290,292,300,301,310,311,315,323,320,319,354,368,371,380,386,376,375,388,403,416,418,424,427,434,438,431,451,450,441,461,459,455,468,472,493,495,484,519 1241,195,812,216,1367,2818,815,484,2739,1275,2740,222,1088,2044,678,1464,2158,319,441,1673,1019,3070,177,59,729,702,1277,1833,1204,141,1998,1674,785,1785,81,468,817,455,164,2103,1787,869,2977,2292,2781,42,1889,64,1208,561,1788,388,1738,1677,507,684,1627,1281,577,3252,18,2209,2346,17,1210,3182,310,249,2747,2909,1248,2109,4,2629,239,3395,705,2711,3334,1,3076,1570,1842,1341,985,375,123,145,2398,354,2450,28,598,1250,184,431,873,874,2453,315,1958,600,376,1376,79,1174,156,2114,1029,2673,2716,2632,493,3356,1799,1845,2797,706,789,1346,948,2798,2012,2633,1641,472,2982,1689,1529,35,1380,2551,1963,86,198,1533,1691,87,256,368,821,320,3098,495,1964,301,879,1138,1802,1487,22,2559,3185,768,272,311,43,688,3282,424,710,2724,241,290,2,990,89,1259,101,434,146,403,202,31,1702,1703,192,1032,3339,3274,514,541,380,653,1654,1914,3187,773,450,586,883,459,70,2067,140,1541,185,273,3383,1442,151,852,1443,32,2184,210,2242,1658,544,568,193,416,1588,2644,39,912,1112,2993,274,999,2690,2132,2071,1661,588,2074,2188,461,323,718,1188,61,569,2997,281,208,451,3176,221,292,3244,1038,1113,633,2767,24,744,1316,15,1401,139,2733,2524,371,673,214,275,1770,3403,427,746,1457,1598,3289,1150,1268,1009,418,834,3358,2325,695,137,1871,2086,519,127,2967,2331,890,235,1010,1041,676,386,531,1195,1876,2897,107,1360,438,215,1118,1509,1119,557,2039,558,1510,1511,85,973,638,1082,133,2381,269,1728,180,811,1777,300,1778 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5484830852023,-0.12887118746947637,-1.9633114577538548,0.7597604826477616,0.406945511095729,0.005176812076117423,-0.061384384139230704,-1.1906923971648218,0.15704238472925763,0.09253370913532158,0.24175657929060165,0.7786548166059916,0.3456433744169804,-1.4237405696271823,-0.38473594847995757,0.447397619113444,2.1028225946561765,-0.17439114903384173,-0.2667413189986047,0.6448869477951056,2.1899853400179143,-0.7574012545226345,-0.38473594847995757,0.3043501904123781,1.3995215238872651,0.24175657929060165,0.22071433819033928,0.4675011541744141,0.8349190753908383,0.6254843056815558,0.13563368348203628,-0.17439114903384173,-0.7059762210511288,2.4019708945127647,0.04905067418434559,0.7407953762815624,1.4659622290827485,0.17835812614782434,-0.01690917370953021,0.17835812614782434,0.5864529093583782,-0.24348703633272678,0.5864529093583782,-0.01690917370953021,-0.01690917370953021,2.685636217276718,0.2627094020641012,0.5074668730496471,0.19958181332532843,2.1610865858455655,-0.40868858056019347,1.1949644490190432,-0.10627094673633292,1.6603878760836814,0.3661616464083245,-0.12887118746947637,1.0895765601315317,-0.12887118746947637 3430 Transporter activity 81 173 5.68912431511688 1.2769248660942864e-08 Q9NS69,P53985,L0R6Q1,Q9H9B4,P45880,P30536,Q07820,P21796,O43676,O60830,P06576,O75964,Q9UM00,Q8TB61,Q14849,Q9C0H2,Q9UBX3,Q96GC9,Q99595,Q96ES6,Q9Y584,P04062,Q8WTV0,P03886,Q03518,Q9UDW1,Q9Y487,Q70HW3,O15118,P17900,O15173,Q9H2D1,O14925,Q13423,Q93050,Q9HD20,P38435,Q9H2V7,Q9P0J0,O43772,O95202,Q9BSK2,P13073,Q8IXU6,P24539,P12235,P47985,Q03519,P00403,P12236,P30825,O14678,Q6P4A7,P16615,Q7KZN9,Q9Y619,P20020,Q9Y277,P49755,Q9BXW6,P51798,Q96NB2,Q15388,Q07812,Q99797,Q8NE01,Q9NUT2,P55011,P14854,Q9BQT8,Q15043,Q9Y5J9,Q8NE86,P08183,O43681,P56385,Q7Z3C6,Q9Y6M9,P51970,O43808,P05141 Functions GO Molecular function msigdb_gomf 3,509,504,530,13,12,525,20,25,30,536,33,558,39,43,45,50,569,56,57,62,68,71,74,86,92,94,97,98,104,117,120,122,130,136,137,145,148,149,152,154,165,178,179,183,182,191,198,213,218,225,222,247,249,257,266,278,294,315,324,335,352,355,368,384,381,398,394,392,409,415,420,425,429,428,446,459,482,492,486,488 504,1086,2859,1941,2739,222,122,678,98,117,1019,25,2975,428,152,486,30,623,2387,1206,3093,681,2438,1369,3268,33,3150,839,3215,154,2620,937,978,2293,213,74,68,897,488,536,3234,2785,3372,429,2164,1245,2049,1739,595,182,218,178,392,249,104,3048,278,2296,1475,3333,20,1248,1049,183,2214,1286,3112,12,225,1051,2001,1094,145,2546,13,191,3255,873,315,3362,335,492,2058,2587,1290,509,394,2588,446,2360,2012,1482,1690,582,1294,739,86,198,368,525,130,2404,565,2986,43,415,355,1699,2837,905,608,3368,1182,3187,247,1107,97,257,459,1393,179,1712,381,425,39,71,802,136,57,569,352,1038,1315,2137,56,384,2963,3319,409,165,1770,1717,1006,324,746,45,1150,2034,120,148,2850,530,137,2574,3,398,149,50,92,1509,2491,967,558,2200,294,94,62,420,639,266,3330,619,482 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3430 Transporters 116 369 4.972938604134393 6.594555095094276e-07 P55060,P24390,P53985,O60831,Q9H9B4,P45880,Q2M389,P46934,Q6NTF9,Q14108,Q99720,Q9H061,O60637,Q5BJF2,Q8N511,O75955,Q9UM00,Q8TB61,Q14849,O76094,Q9C0H2,Q5VW38,Q9UBX3,Q8WTV0,P07602,Q8WY22,O75844,Q03518,Q15629,Q70HW3,O15118,Q9BTX1,Q9H2D1,Q15070,Q9Y3B3,Q93050,Q9HD20,Q9H2V7,O43772,O95202,P52292,Q9BRK5,P57105,O15127,Q9BSK2,Q9Y287,Q9Y6C9,Q96P70,P13073,Q8IXU6,O96005,P12235,Q5T9L3,Q03519,P13473,P00403,Q9UBU6,Q9BUN8,P12236,Q96PC5,P30825,P05067,O14678,Q15363,Q9NZJ7,Q6P4A7,P16615,Q8IYU8,P54646,Q07065,Q13277,Q9Y619,Q9BUR5,P20020,Q8TBA6,P21912,Q96RL7,Q9NR77,Q13190,P49755,Q96A33,Q16625,O15260,P51798,O15397,Q96NB2,Q8TAA9,Q07812,Q96KP1,Q8NE01,P35613,Q9NUT2,P55011,P14635,Q9BQT8,P11279,Q15043,Q8NHH9,Q9C0E2,Q9H3N1,Q9Y512,Q15904,P08183,O43681,Q96N66,O95067,Q969V3,Q92973,Q7Z3C6,O76024,Q6ZXV5,P57088,P50570,O43808,P05141,Q9NPA0 Functions Protein Atlas Protein class protein_atlas_protein_class 510,4,509,505,530,13,527,524,541,22,24,26,27,31,32,534,558,39,43,550,45,48,50,71,77,80,81,86,89,97,98,105,120,126,133,136,137,148,152,154,156,160,162,163,165,166,167,176,178,179,181,182,192,198,196,213,215,214,218,221,225,224,222,241,243,247,249,250,254,256,260,266,275,278,286,282,292,297,301,315,323,322,319,335,340,352,364,368,370,381,375,398,394,391,409,413,415,416,417,418,419,434,429,428,451,442,461,460,459,455,477,493,491,486,488,519 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3430 Transmembrane transport 90 213 4.964943575787215 6.87210465383364e-07 Q13546,Q9NS69,P53985,O60831,L0R6Q1,Q9H9B4,P45880,Q07820,P46934,P21796,O60830,P06576,O75964,Q9UM00,Q8TB61,Q9C0H2,O75381,Q9UBX3,Q96GC9,Q14728,Q99595,Q96ES6,Q9Y584,Q6YHU6,P23786,P04062,Q8WTV0,Q00535,Q4KMQ2,O75844,Q03518,Q15629,Q9Y6M7,Q9UDW1,Q70HW3,Q9UHG3,P78417,Q9H2D1,O14925,Q13423,Q9HD20,P38435,Q9H2V7,O43772,O95202,Q9BSK2,P13073,Q8IXU6,P24539,P12235,P47985,Q03519,P00403,P12236,P30825,P05067,O14678,P52789,Q6P4A7,P16615,Q8IYU8,Q7KZN9,P42858,Q9Y619,P20020,Q9Y277,P0DP25,P49755,Q16625,Q9P2D1,P51798,Q96NB2,Q15388,Q07812,Q99797,Q99623,Q8NE01,Q9NUT2,P55011,P14854,Q9BQT8,Q15043,Q15041,Q8NE86,P08183,P56385,P50570,O43808,P05141,Q9UJZ1 Processes and pathways GO Biological process msigdb_gobp 512,3,509,505,504,530,13,525,524,20,30,536,33,558,39,45,549,50,569,565,56,57,62,586,63,68,71,582,608,81,86,89,619,92,97,100,103,120,122,130,137,145,148,152,154,165,178,179,183,182,191,198,213,218,225,224,222,236,247,249,250,257,259,266,278,294,304,315,322,339,335,352,355,368,384,383,381,398,394,392,409,415,424,425,429,446,491,486,488,520 504,2043,2859,2738,1941,222,122,728,1996,152,486,702,2437,30,505,623,2941,2387,2860,549,2900,1369,81,817,3268,33,3150,154,937,730,2293,213,68,897,224,488,2665,1335,536,3234,2785,2390,1628,3372,429,2164,1245,2049,304,1739,3398,595,1126,3236,182,218,178,392,249,1247,2536,2746,2667,278,2296,1475,3333,3219,20,1049,63,183,2214,1520,2710,1286,3113,3076,225,1051,1842,3348,2001,1094,145,2546,259,13,524,1374,191,3255,315,2009,1574,1479,491,335,236,1290,509,1058,2170,394,2588,446,3356,2718,2360,2012,1031,103,1690,582,1294,739,86,198,2229,2119,1252,368,525,2636,1645,130,512,1802,2233,565,2986,1909,424,415,1064,355,89,1699,322,1912,991,608,1182,3187,247,1107,586,2024,97,257,3284,1393,3383,179,250,997,381,425,39,2993,71,1352,802,57,569,2997,352,1594,1113,3318,633,56,383,384,2963,1502,409,165,1770,1006,3369,746,45,1150,120,148,2144,2850,530,2851,137,924,2574,3,398,339,50,92,1509,1933,100,2491,967,520,558,294,1327,2431,2155,62,266,3330,619 0.6448869477951056,-0.2667413189986047,-0.7059762210511288,-0.6298806123677426,-0.22034471621492466,1.4328472746723286,2.233047134387105,0.406945511095729,-0.24348703633272678,1.8937948621783494,0.6642150900524303,0.4272126540305929,-0.4569583228314796,3.684618516209035,0.6448869477951056,0.5074668730496471,-0.7574012545226345,-0.4327622425712757,-0.7059762210511288,0.5864529093583782,-0.7316181307528602,0.027163091494653614,2.7510864124399865,0.3456433744169804,-1.1623836255706177,3.5731076371518076,-0.9689694457036316,1.8785482781004688,0.2627094020641012,0.406945511095729,-0.38473594847995757,1.4659622290827485,2.993031551841918,0.28357365910325655,1.4328472746723286,0.6642150900524303,-0.5798253703616462,0.04905067418434559,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-0.4327622425712757,-0.08377571033449493,-1.5143297421023834,0.7407953762815624,-0.31359071053648363,0.09253370913532158,-0.2667413189986047,1.0539628363107982,-0.12887118746947637,-1.7976755345030844,0.5273305006198339,0.15704238472925763,-1.1062863390031978,1.6444566286616846,1.4494309133701686,1.6603878760836814,0.816233531485841,1.2640484788395443,0.09253370913532158,-0.5057234167351391,-0.6298806123677426,-0.5798253703616462,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,-1.0784930750204527,3.9859536481432736,0.19958181332532843,3.0673208707632353,1.6444566286616846,-0.3371883420413084,-0.03909589167063334,-0.6047865559806115,0.07084055395748909,-0.9151668939436284,-0.8619817453617755,1.4328472746723286,0.19958181332532843,-0.17439114903384173,-1.3643448569490237,-0.24348703633272678,0.17835812614782434,2.0142315842992913,-0.5057234167351391,1.2296215579874639,4.222429217331235,0.6254843056815558,0.027163091494653614,1.5963727964305452,-1.1342490728645735,1.0181005541038732,-0.24348703633272678,-0.061384384139230704,-0.01690917370953021,0.6642150900524303,0.945614424806558,1.382778649014379,0.07084055395748909,0.6448869477951056,0.19958181332532843,-0.31359071053648363,0.816233531485841,-0.5302953342350691,0.7217588966997998,-1.4237405696271823,-0.6047865559806115,-0.40868858056019347,-0.24348703633272678,0.22071433819033928,2.4708459283490147,-0.10627094673633292,0.5471155860670778,0.07084055395748909,0.406945511095729,2.672453216244307,1.5640718300941014,-0.3371883420413084,-0.2901087935675131,0.09253370913532158,0.8535361731217637,0.6254843056815558,-0.5549954789805401,-0.08377571033449493,2.1610865858455655,0.6448869477951056,-0.151577544698465,-0.3371883420413084,0.5668228264787173,-0.7833273588538234,-0.19731314994998111,0.7597604826477616,0.7786548166059916,0.19958181332532843,0.8905672747951905,2.632715285689517,-0.10627094673633292,1.000074973722675,-0.19731314994998111,0.24175657929060165,0.5273305006198339,0.13563368348203628,-1.023405807478901,1.2811766906485145,0.17835812614782434,0.5471155860670778,-0.24348703633272678,2.552373754198136,1.2468635762934643,-1.1906923971648218,0.027163091494653614,-1.6067879521771078,1.6603878760836814,1.2640484788395443,0.24175657929060165,0.8349190753908383,0.7597604826477616,3.482324846985818,-0.7833273588538234,2.917749605386218,0.04905067418434559,0.3661616464083245,3.1527758461637907,0.5668228264787173,-0.7833273588538234,0.9089823832894932,-0.061384384139230704,0.17835812614782434,-1.2766888241918128,0.5074668730496471,3.1648792186751504,0.8349190753908383,0.8349190753908383,-0.7574012545226345,-0.01690917370953021,0.7974789711276091,1.8171233074337798,-0.12887118746947637,0.24175657929060165,-1.4839299067547875,0.406945511095729,3.3784536775429674,0.15704238472925763,2.2615667415404976,1.9392759124745347,-0.2901087935675131,-0.6804737926663148,0.6254843056815558,-0.6804737926663148,2.1028225946561765,0.28357365910325655,-0.5057234167351391,4.706308247813215,0.816233531485841,0.945614424806558,3.2845170686821423,2.6194057651180533,-0.01690917370953021,-0.19731314994998111,2.5388692262913795,-0.4569583228314796,0.2627094020641012,0.6448869477951056,0.5864529093583782,1.107291420206707,0.07084055395748909,-0.4327622425712757,-0.2901087935675131,3.0796079772709244,1.2123219939175685,-1.3057195477388794,0.5273305006198339 3430 Transporter 68 182 4.781509987633798 1.7398335752094596e-06 Q9HD45,O95249,Q9Y3B3,P24390,P53985,Q13277,Q9NUT2,Q93050,P55011,Q9Y619,Q9H9B4,Q9BQE5,Q9H2V7,Q9BQT8,P20020,O43772,O95202,P52292,P11279,P06576,Q15043,Q14444,Q9C0E2,O15400,Q9BSK2,Q9BVK6,Q9Y6C9,Q8TB61,Q13190,Q9UBX3,Q8IXU6,P08183,P24539,Q96ES6,P12235,O43731,O95487,P49755,Q9Y584,P56385,Q03519,P13473,Q92973,Q03518,P12236,Q9Y6M7,Q9Y487,P30825,Q96NB2,Q70HW3,O14678,P11166,Q15388,P17900,Q9P2W9,Q12907,Q99523,O00203,Q15363,O43808,Q9Y5K8,Q9NZJ7,P05141,Q92544,O75027,Q9H2D1,P16615,Q15070 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 129,258,133,4,509,260,398,136,394,266,530,15,148,409,278,152,154,156,413,536,415,289,417,532,165,427,167,39,301,50,179,429,183,57,182,59,561,315,62,446,198,196,460,86,218,619,94,225,352,97,222,595,355,104,107,495,633,483,241,486,639,243,488,629,623,120,249,126 2043,483,1731,1943,815,1831,1275,659,222,1123,678,532,59,152,486,622,2099,2940,932,1784,623,1737,1369,3268,2103,2781,154,258,1889,1208,561,937,2293,897,488,536,429,2164,3217,3151,595,413,182,218,196,249,104,278,1475,3333,1049,4,183,2214,1286,3017,225,1341,2001,3050,2546,1250,873,874,315,1479,1376,1174,156,3131,1290,2114,1029,1480,509,2673,901,2170,2796,394,2588,446,2507,2360,2012,1641,2677,1690,1531,1576,739,86,198,1430,2013,1643,1644,495,301,260,2512,2232,289,3133,415,126,3158,1064,241,355,1699,3368,1182,3187,97,2479,714,179,1585,1445,39,2690,828,1446,2132,629,801,460,136,803,1231,57,352,2483,1450,633,2137,2963,15,409,3162,165,427,1006,417,1150,1008,120,148,2850,530,129,2574,2089,398,925,243,3005,1876,1989,107,1360,1825,50,2491,2427,967,1121,2700,725,1827,1408,1082,133,94,62,639,1728,266,811,167,619 -0.2667413189986047,0.6642150900524303,-0.12887118746947637,-0.22034471621492466,0.3456433744169804,-0.17439114903384173,0.07084055395748909,0.4675011541744141,1.4328472746723286,0.15704238472925763,0.447397619113444,0.6060065128039738,3.104102422844003,1.8937948621783494,0.6642150900524303,0.5074668730496471,-0.2901087935675131,-0.7574012545226345,0.2627094020641012,-0.151577544698465,0.5074668730496471,-0.12887118746947637,0.027163091494653614,-1.1623836255706177,-0.2901087935675131,-0.6551091457204445,1.8785482781004688,1.2296215579874639,-0.19731314994998111,0.11413110287400714,0.5668228264787173,0.2627094020641012,-0.38473594847995757,0.28357365910325655,0.6642150900524303,0.6060065128039738,0.7407953762815624,-0.31359071053648363,-1.0784930750204527,-0.9689694457036316,0.5273305006198339,0.7786548166059916,1.6444566286616846,1.4494309133701686,1.5640718300941014,1.2640484788395443,2.4571398271524862,1.1600736506845353,-0.01690917370953021,-1.3349373118137702,0.19958181332532843,4.687680585731818,1.6444566286616846,-0.3371883420413084,0.07084055395748909,-0.8093982448803362,1.4328472746723286,0.04905067418434559,-0.24348703633272678,-0.8356157493053581,-0.5057234167351391,0.09253370913532158,0.3043501904123781,0.3043501904123781,1.0181005541038732,-0.01690917370953021,0.027163091494653614,0.13563368348203628,1.8632581140200792,-0.9419899846973533,0.07084055395748909,-0.2901087935675131,0.22071433819033928,-0.01690917370953021,0.6448869477951056,-0.5798253703616462,0.28357365910325655,-0.31359071053648363,-0.6551091457204445,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.4812782346091039,-0.40868858056019347,-0.24348703633272678,-0.08377571033449493,-0.5798253703616462,-0.10627094673633292,-0.03909589167063334,-0.061384384139230704,0.406945511095729,2.672453216244307,1.5640718300941014,0.005176812076117423,-0.24348703633272678,-0.08377571033449493,-0.08377571033449493,0.6642150900524303,1.071800525038966,1.2296215579874639,-0.4812782346091039,-0.3371883420413084,1.1249455781236504,-0.9419899846973533,0.7786548166059916,2.1899853400179143,-0.9689694457036316,0.19958181332532843,1.3491309609547064,0.8905672747951905,-0.10627094673633292,-1.4839299067547875,0.13563368348203628,-1.023405807478901,2.552373754198136,-0.4569583228314796,0.4272126540305929,1.6603878760836814,-0.061384384139230704,0.005176812076117423,3.482324846985818,-0.5798253703616462,0.3456433744169804,0.005176812076117423,-0.2901087935675131,0.5074668730496471,0.3661616464083245,0.7026504351173741,2.1174474931929272,0.3661616464083245,0.11413110287400714,3.1527758461637907,0.9089823832894932,-0.4569583228314796,0.005176812076117423,0.5074668730496471,-0.2901087935675131,-0.7574012545226345,4.131016779152228,0.7974789711276091,-0.9689694457036316,1.8171233074337798,0.7597604826477616,0.24175657929060165,0.7786548166059916,0.15704238472925763,0.24175657929060165,2.2615667415404976,1.9392759124745347,-0.6804737926663148,0.6254843056815558,2.1755552047661753,-0.5057234167351391,-0.2667413189986047,0.816233531485841,0.28357365910325655,1.3322253587909487,-0.7833273588538234,-0.17439114903384173,-0.22034471621492466,2.4019708945127647,0.04905067418434559,-0.151577544698465,3.2845170686821423,-0.4569583228314796,-0.4327622425712757,0.2627094020641012,0.17835812614782434,-0.5798253703616462,0.4272126540305929,-0.151577544698465,0.027163091494653614,0.19958181332532843,2.1610865858455655,2.6060641851362782,3.0796079772709244,0.5074668730496471,-0.10627094673633292,1.2123219939175685,0.3661616464083245,1.8016559746006866,0.5273305006198339 3430 Golgi apparatus 39 183 4.718851700677627 2.3717963770764072e-06 P80303,Q9HD45,P54646,P24390,Q93050,Q9H4A6,Q8N4Q0,P09601,O95302,Q9H2V7,O00461,Q8N4A0,O60637,Q8TBA6,Q9BRK5,P55327,P67812,Q02818,Q9H8H2,P16278,O15127,Q9Y287,Q13190,Q5VW38,Q8IXU6,P50897,Q9HB40,Q9NPR9,P49755,Q9NWM8,A1L0T0,P53367,Q8NBN3,Q9UBU6,O75071,P05067,Q13535,O60512,Q8IZA0 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 0,129,254,4,136,268,16,17,147,148,23,153,27,286,160,288,35,36,37,38,163,166,301,48,179,53,55,58,315,325,195,209,212,215,90,224,230,231,237 195,812,1614,483,813,23,1275,1779,2158,163,660,816,319,1780,3069,3110,3091,3092,621,1833,231,27,1784,2344,703,90,1736,2942,534,442,2498,147,683,1738,684,224,551,17,1338,2624,2210,374,38,1165,1248,4,2052,1568,2446,2543,1341,1342,1748,2218,2505,2005,1250,315,1479,491,601,53,2951,843,209,2114,1029,254,288,3317,35,0,1752,1532,36,2460,3025,1430,821,2013,301,1179,230,2594,1384,2917,709,605,1910,415,554,2956,2023,2838,48,1759,881,1707,541,653,1654,1914,627,2602,742,3081,497,1144,1145,1494,714,2365,2183,179,743,611,237,529,153,16,853,2241,212,2025,1186,286,999,1762,1447,365,802,136,1230,1922,1764,1035,1036,1549,1315,633,1595,2767,1502,3161,160,2324,1717,3065,1268,2651,148,1666,2248,268,3358,37,2325,411,3249,55,129,1820,2086,58,861,2331,862,890,1459,781,325,437,215,1878,2857,1934,1462,2530,969,166,2815,1882,811 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3430 Endoplasmic reticulum 87 204 4.673782937916356 2.957018557792068e-06 O60831,O43169,Q9P035,P43307,Q5BJF2,Q9UM00,O95197,Q14849,Q9H3G5,Q96GC9,Q8NF37,O43731,Q96G23,O95470,Q8WUJ1,P27635,Q86UE4,P62917,P51648,Q03518,Q9Y680,Q15800,P50402,Q9P2W9,P37268,Q9NQC3,Q86XL3,P46778,P26373,Q16850,P13674,Q8N0U8,Q9NZ01,P67809,P62820,P20042,O76062,Q9HCU5,O43292,O96005,P14859,Q5T9L3,Q96AG4,P42766,Q03519,Q15631,Q96KC8,P27824,P61513,Q9BUN8,O00264,Q99735,Q96PC5,P62277,P36578,Q14257,P62847,P27544,Q9NR31,P62750,Q5HYI8,Q8IV08,Q8TCT9,Q96HY6,P62841,Q9Y6B6,Q96KA5,Q96A33,O15260,Q96CN7,Q9BT22,P51571,Q15043,Q8NHH9,Q9H3N1,Q15041,Q9Y3U8,Q9UBM7,P48651,P83731,P21964,O15269,Q13409,P62266,P47914,O75845,O00767 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 505,10,531,28,31,558,42,43,49,569,568,59,61,64,66,578,70,580,79,86,95,101,600,107,123,127,140,645,643,146,641,151,676,665,664,663,164,695,177,181,190,192,718,197,198,712,208,705,707,214,216,744,221,738,736,233,238,239,248,255,265,273,274,281,283,300,303,323,319,343,371,376,415,416,418,424,440,438,431,448,445,441,458,457,456,468,484 216,484,2044,2158,319,441,1124,10,3070,177,59,729,1205,505,933,1785,468,817,164,1787,2977,42,1889,64,181,1677,1627,1281,3279,2665,1790,1469,1471,2049,3013,3126,641,2212,3182,190,980,2747,1091,1164,663,3346,445,3347,1841,643,239,578,3395,705,1521,3334,2262,2447,1341,985,736,123,2398,197,28,899,1523,645,900,1053,456,431,1478,874,600,2548,1135,376,1376,79,3356,1175,1688,1640,707,2012,2633,949,1176,2362,1642,457,738,2456,255,764,664,283,238,1291,2754,1060,902,580,1425,3281,665,448,846,1576,86,198,2460,952,3098,1300,1431,458,879,1487,233,3185,3027,1907,43,1909,424,415,2724,2681,712,1259,101,146,3259,31,265,192,3274,1654,1536,956,773,883,70,2067,140,1541,273,1442,151,2184,2762,568,416,1588,1112,274,2520,66,1661,1920,323,718,343,1188,2418,61,569,281,303,208,221,1038,1113,744,1316,805,2524,371,214,1457,1598,1718,1268,49,418,695,127,248,2197,676,531,1876,2897,107,438,1670,2933,1509,558,440,95,300 1.4494309133701686,0.6642150900524303,-0.2667413189986047,-0.31359071053648363,1.000074973722675,0.7217588966997998,0.15704238472925763,4.3124581612681805,-0.8619817453617755,1.6603878760836814,3.104102422844003,0.406945511095729,0.11413110287400714,0.6448869477951056,0.2627094020641012,-0.151577544698465,0.6834693746272135,0.3456433744169804,1.8171233074337798,-0.151577544698465,-0.7833273588538234,3.4479092742401036,-0.19731314994998111,3.0426662360183325,1.6444566286616846,-0.10627094673633292,-0.08377571033449493,0.07084055395748909,-1.1906923971648218,-0.5798253703616462,-0.151577544698465,-0.01690917370953021,-0.01690917370953021,-0.2667413189986047,-0.8093982448803362,-0.9419899846973533,0.487523996503178,-0.3371883420413084,-1.023405807478901,1.5963727964305452,0.24175657929060165,-0.6298806123677426,0.17835812614782434,0.13563368348203628,0.4675011541744141,-1.3643448569490237,0.7217588966997998,-1.3643448569490237,-0.17439114903384173,0.487523996503178,1.3491309609547064,0.5471155860670778,-1.7012045060061012,0.4272126540305929,-0.03909589167063334,-1.3349373118137702,-0.36090298236806184,-0.4569583228314796,0.04905067418434559,0.24175657929060165,0.406945511095729,2.2187310778900433,-0.4327622425712757,1.5640718300941014,3.706665868419647,0.28357365910325655,-0.03909589167063334,0.487523996503178,0.28357365910325655,0.19958181332532843,0.7026504351173741,0.7407953762815624,-0.01690917370953021,0.3043501904123781,0.5273305006198339,-0.5057234167351391,0.15704238472925763,0.8349190753908383,0.027163091494653614,2.777052623692763,-1.4237405696271823,0.13563368348203628,-0.10627094673633292,-0.08377571033449493,0.4272126540305929,-0.24348703633272678,-0.5549954789805401,0.2627094020641012,0.13563368348203628,-0.40868858056019347,-0.08377571033449493,0.7026504351173741,0.406945511095729,-0.4569583228314796,1.2468635762934643,0.3865954317326442,0.4675011541744141,1.1425395010761892,1.3659819254553316,0.07084055395748909,-0.6298806123677426,0.19958181332532843,0.28357365910325655,0.5471155860670778,0.005176812076117423,-1.1906923971648218,0.4675011541744141,0.7217588966997998,0.32503982365867656,-0.061384384139230704,2.672453216244307,1.5640718300941014,-0.4569583228314796,0.2627094020641012,-0.8884981438055674,0.07084055395748909,0.005176812076117423,0.7026504351173741,0.3043501904123781,-0.01690917370953021,1.3995215238872651,-1.023405807478901,-0.8093982448803362,-0.19731314994998111,3.413286496271575,-0.19731314994998111,0.7597604826477616,0.7786548166059916,-0.6047865559806115,-0.5798253703616462,0.4272126540305929,0.09253370913532158,2.5117605953310402,2.0142315842992913,-1.1342490728645735,3.6735633983186133,1.2123219939175685,1.5963727964305452,-1.1623836255706177,-0.08377571033449493,-0.03909589167063334,0.2627094020641012,0.3865954317326442,0.3043501904123781,2.9555165253944415,-0.2667413189986047,2.073453552149814,-0.03909589167063334,1.1775484830852023,0.005176812076117423,1.908998145444964,-0.31359071053648363,-0.6298806123677426,0.5668228264787173,0.7786548166059916,-0.061384384139230704,0.17835812614782434,1.1775484830852023,-0.4812782346091039,3.0302984430490625,-0.08377571033449493,-0.19731314994998111,1.000074973722675,0.4272126540305929,0.9273312549578325,0.13563368348203628,-0.4327622425712757,3.104102422844003,0.5668228264787173,1.1600736506845353,1.071800525038966,1.5152459271739311,1.4494309133701686,0.22071433819033928,0.17835812614782434,0.406945511095729,0.07084055395748909,0.3661616464083245,-0.4812782346091039,0.8535361731217637,1.4659622290827485,0.005176812076117423,-0.061384384139230704,-0.10627094673633292,0.09253370913532158,3.3551136813137883,0.7786548166059916,0.447397619113444,2.1899853400179143,1.2811766906485145,-0.31359071053648363,0.4675011541744141,0.6254843056815558,-0.17439114903384173,-0.7059762210511288,2.4019708945127647,0.7407953762815624,-0.08377571033449493,-0.7316181307528602,-0.01690917370953021,0.5864529093583782,0.7407953762815624,2.592690371019141,1.0895765601315317 3430 Mitochondrial envelope 104 320 4.6654860467880335 3.078883891838302e-06 Q9NS69,P14406,O43169,Q69YU5,P30536,P45880,Q9H9B4,Q07820,P09601,P17931,P21796,O43676,Q9H061,Q16134,Q8N4H5,O60830,P06576,O75964,Q9UBX3,Q99595,Q9Y584,P23786,Q9BXK5,P03886,Q13505,Q9Y2R0,Q8WY22,O14949,Q96A26,Q9UDW1,Q70HW3,Q9UDX5,P22695,Q9H2D1,O14925,Q15070,Q8N2A8,Q13423,Q8NAN2,Q9H2V7,Q9P0J0,Q567V2,O43772,O95202,P57105,Q9BSK2,Q9Y6C9,P13073,P24539,P12235,Q86Y39,P47985,Q7Z7H8,Q9Y5L4,P00403,O00264,P12236,Q9NZ45,P49748,Q9NUQ2,P52789,Q9NZJ7,Q6P4A7,Q8IYU8,Q7KZN9,Q96CU9,Q9Y619,Q9H4A6,Q9BUR5,Q6DKK2,P21912,Q96RL7,Q9Y277,P0DP25,Q99536,Q96NB2,Q8TB36,P42345,Q15388,Q5XKP0,Q96AY3,Q07812,Q9NPL8,Q99623,Q9NVI7,Q9P032,Q9NUT2,Q96IX5,P14854,Q9BQT8,Q9Y512,Q9Y5J9,Q8NE86,O15228,Q9BWH2,P56385,P04818,Q9Y6M9,Q14197,P22830,Q9BUK6,P51970,P05141,Q9UJZ1 Localization GO Cellular component msigdb_gocc 3,9,10,11,12,13,530,525,17,523,20,25,26,539,29,30,536,33,50,56,62,63,73,74,75,76,80,82,88,92,97,102,106,120,122,126,132,130,142,148,149,150,152,154,162,165,167,178,183,182,188,191,201,204,213,216,218,227,232,235,236,243,247,250,257,263,266,268,275,280,282,292,294,304,316,352,351,354,355,357,366,368,372,383,385,399,398,396,392,409,419,420,425,421,454,446,443,482,475,470,501,492,488,520 1086,216,1367,1941,699,3404,3278,122,82,421,2776,10,728,25,2975,152,533,1467,1833,30,623,2387,1206,2860,3093,758,681,2900,2438,2101,2663,1369,935,3268,33,2259,3150,839,3215,154,2620,937,1788,730,978,2293,1677,213,74,840,443,488,536,2864,1245,1246,2391,17,2666,304,1739,3398,3413,182,218,3390,178,9,392,3127,3128,2536,3280,523,2747,2393,3048,2296,20,282,2790,106,470,1841,63,183,2214,3112,2350,3113,12,2866,1051,1842,2396,1955,1342,2001,2545,3416,3373,1573,354,2003,13,191,3255,3170,232,3362,1172,1574,2586,492,236,2795,2224,1290,686,2911,1423,2912,2588,446,162,903,820,791,2117,878,2873,792,1177,988,1690,3024,1850,739,368,525,1298,2015,767,1485,130,75,475,3240,3185,768,126,1698,355,3134,539,2837,905,666,991,1701,797,150,1105,798,3260,357,11,280,2179,1182,2728,247,2991,585,1183,1307,97,257,2920,1538,201,1541,188,1392,1973,1543,250,1229,911,132,1586,29,2184,3357,142,716,1712,1812,425,2070,351,2993,1352,80,2606,1763,2073,1398,88,2075,366,2847,1074,263,3225,2077,1864,2027,396,352,292,2032,1817,3318,316,56,383,920,409,634,165,3177,501,275,3427,454,2696,73,745,1189,3032,1551,1357,2140,3000,1664,1981,26,2485,120,148,3066,3190,268,2037,2850,835,530,2526,2327,2851,2612,2086,2376,372,1403,2330,963,964,2574,617,2331,3,235,398,3004,2424,1321,385,1322,780,3107,1987,3037,1721,227,243,1011,399,149,50,92,102,1878,2857,967,520,1609,294,971,1993,76,3229,2255,973,1828,2616,2858,2041,1726,2816,2155,419,62,2618,420,204,266,167,482 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3430 Golgi apparatus 112 326 4.65431040397643 3.2506679008559303e-06 P80303,Q15392,P24390,P01889,L0R6Q1,P46934,Q6NTF9,Q14108,O00461,Q5VYK3,Q02818,Q9H8H2,P16278,Q16706,Q8TB61,Q9UM00,O95197,Q9UL01,P07305,Q5VW38,P50897,Q8NF37,Q9NPR9,O43731,P20337,P04062,Q9Y282,Q9UQB8,Q14789,O15118,P11166,Q9P2W9,P50851,O14773,Q99523,O75503,Q92544,O60645,O60476,O75592,Q6P6C2,Q8N2A8,Q9Y3B3,Q8IY95,Q93050,Q01968,Q8N4A0,P52292,O14617,Q9BRK5,P62820,O15127,Q7Z6Z7,Q9Y287,Q9H7Z7,Q7LGA3,O95456,P04439,Q96M27,Q86Y82,Q92542,Q5T9L3,Q9NQX7,Q15042,O75063,P53367,P61019,Q8NBN3,Q6ZRP7,Q9NX40,P05067,Q13535,O60512,O43852,O15498,Q96L58,Q8IZA0,Q15363,O43505,Q9NR31,P54646,O95249,P42858,Q9H4A6,Q8IV08,Q9BUR5,Q8TBA6,Q15382,Q96RL7,Q9Y6B6,Q13190,P49755,Q10472,O15260,Q658Y4,P42345,Q92896,P35613,P06280,Q9H9S5,Q9BQS8,Q9BVK6,Q92974,Q7Z3C6,Q9BTU6,Q96SN8,P18085,P49327,Q12907,O00203,P50570,Q9BTV4 Localization GO Cellular component msigdb_gocc 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3430 Intrinsic component of organelle membrane 62 124 4.563325746208363 5.03496013748439e-06 P01889,L0R6Q1,Q9P035,Q9H9B4,Q86XL3,Q9Y4P3,Q8TCT9,Q9BUR5,Q6NTF9,P20020,Q16134,O60830,P57105,O43819,P42892,O76062,Q9UM00,Q9Y287,Q9Y512,Q8TB61,Q15041,Q8NE86,Q9UBM7,O43292,Q86YN1,Q99595,Q14739,P20337,P12235,Q9BWH2,Q96A33,Q92643,O95470,Q5T9L3,P61020,Q03519,P13473,Q6UXV4,Q13505,Q9Y2R0,O94901,O76024,O75844,Q9Y282,Q03518,Q9BUN8,Q15629,Q96NB2,Q8TB36,O15118,Q15388,P57088,Q5XKP0,O43808,O00767,O43505,Q6P4A7,O14925,Q9NPA0,Q9BTV4,Q15070,Q9NQC3 Localization GO Cellular component msigdb_gocc 507,504,531,530,140,269,274,275,541,278,539,30,162,533,161,164,558,166,419,39,424,425,438,177,185,56,311,562,182,454,323,588,64,192,447,198,196,585,75,76,574,455,81,85,86,214,89,352,351,98,355,493,357,486,484,246,247,122,519,517,126,127 1241,504,484,122,678,98,816,1019,177,246,486,533,30,758,81,935,455,164,3150,574,64,937,2293,507,684,1210,182,196,278,562,3395,705,3334,3373,161,1172,1574,1685,1376,493,162,447,2012,1690,86,198,821,75,3185,311,3282,424,126,1434,355,89,539,666,797,1702,906,192,357,541,247,585,742,2067,140,714,185,1392,1393,1973,1543,2242,3387,425,351,39,274,613,588,2188,323,1035,352,3244,1113,56,2524,517,214,275,454,1457,1598,3190,834,530,2327,695,519,127,2574,1321,3037,676,531,1195,2897,438,1878,2857,1406,558,85,166,76,2935,269,2155,419,1777 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3430 Mitochondrion organization 64 200 4.5633147269678735 5.035224525107296e-06 P55786,Q8N2A8,Q9NS69,P42858,Q9P032,Q96CU9,P14406,Q69YU5,P30536,P45880,Q8NAN2,Q9H4A6,Q9BUR5,P21796,Q9P0J0,Q6DKK2,O43676,Q9H061,O95202,Q8N4H5,O60830,Q9Y512,Q96RL7,Q9BSK2,Q9Y5J9,Q9Y6C9,Q8NE86,Q9UBN7,P0DP25,Q9NUQ9,Q99595,P12235,Q9BWH2,O75153,Q86Y39,Q9Y584,P47985,Q99536,P04062,O14737,P03886,Q13505,Q9Y2R0,Q9Y5L4,Q7Z3C6,Q9Y6M9,Q96A26,O14965,Q8TB36,Q15388,Q5XKP0,Q9UDX5,Q9BUK6,P52789,P51970,O00203,Q07812,P27544,Q99797,P05141,Q99623,Q9NVI7,O14925,Q15070 Processes and pathways GO Biological process msigdb_gobp 128,132,3,259,399,263,9,11,12,13,142,268,275,20,149,280,25,26,154,29,30,419,292,165,420,167,425,439,304,314,56,182,454,60,188,62,191,316,68,329,74,75,76,204,459,482,88,467,351,355,357,102,501,236,492,483,368,239,384,488,383,385,122,126 1613,1995,483,1086,1367,329,122,467,728,25,2975,533,1467,30,1368,60,1561,2387,1206,2860,758,681,2900,2438,2208,935,3150,839,154,2620,1413,2820,3295,3193,730,978,2293,2978,732,74,68,3371,2784,488,1161,2391,552,304,3398,2442,182,9,1630,20,239,1520,3112,1631,3113,2215,12,1571,2867,1955,3129,1522,3373,3019,259,13,191,1682,2006,874,2009,1895,1479,601,1376,492,236,128,1799,1426,1216,2983,582,2173,368,1298,75,2917,3240,768,126,1698,355,3134,824,554,2837,905,666,3259,991,797,609,798,2409,357,11,280,585,1183,1069,543,459,1656,667,188,1392,1973,1543,2314,1976,911,132,29,2184,142,425,2959,351,1714,2993,1352,2844,88,263,3102,2027,2483,292,2032,1925,3318,316,56,383,2849,384,3085,165,3177,501,275,454,833,3385,26,3190,268,2037,2851,2330,963,3,1873,314,3004,1321,385,780,3037,399,149,3123,439,102,1878,2857,2149,520,892,1609,76,1776,1828,2041,1883,2382,2155,419,62,2618,420,204,1201,167,482 -0.08377571033449493,-0.24348703633272678,0.6642150900524303,0.17835812614782434,0.027163091494653614,0.9638324211451322,2.233047134387105,0.6834693746272135,0.406945511095729,3.8372261164826145,-0.7833273588538234,0.6060065128039738,-0.01690917370953021,3.684618516209035,0.027163091494653614,3.104102422844003,-0.061384384139230704,-0.4327622425712757,0.11413110287400714,-0.7059762210511288,0.3865954317326442,0.447397619113444,-0.7316181307528602,-0.4569583228314796,-0.3371883420413084,0.2627094020641012,-0.9689694457036316,0.32503982365867656,1.8785482781004688,-0.5549954789805401,0.005176812076117423,-0.6804737926663148,-1.2191778402877913,-1.0508669815631295,0.406945511095729,0.24175657929060165,-0.38473594847995757,-0.7833273588538234,0.406945511095729,2.86699521405523,2.993031551841918,-1.5143297421023834,-0.6551091457204445,0.6642150900524303,0.13563368348203628,-0.4327622425712757,0.5864529093583782,1.0539628363107982,-1.7976755345030844,-0.4569583228314796,1.6444566286616846,4.459556787416143,-0.08377571033449493,3.9859536481432736,1.3491309609547064,-0.03909589167063334,-0.9151668939436284,-0.08377571033449493,-0.9151668939436284,-0.3371883420413084,4.222429217331235,-0.061384384139230704,-0.7059762210511288,-0.22034471621492466,-0.9419899846973533,-0.03909589167063334,-1.5449371974827035,-0.8093982448803362,1.2296215579874639,4.222429217331235,1.5963727964305452,-0.10627094673633292,-0.24348703633272678,0.3043501904123781,-0.24348703633272678,-0.19731314994998111,-0.01690917370953021,0.5273305006198339,0.027163091494653614,0.6642150900524303,1.382778649014379,2.1755552047661753,-0.151577544698465,0.005176812076117423,0.11413110287400714,-0.7833273588538234,0.5471155860670778,-0.31359071053648363,0.8535361731217637,0.07084055395748909,2.854234483045071,-0.7316181307528602,-1.1062863390031978,0.3865954317326442,2.1899853400179143,-0.10627094673633292,0.8905672747951905,-0.9419899846973533,0.3456433744169804,0.5864529093583782,-0.6804737926663148,0.28357365910325655,0.4675011541744141,-1.1342490728645735,0.24175657929060165,0.3661616464083245,0.5273305006198339,0.3661616464083245,-0.4327622425712757,0.8905672747951905,4.282599323100913,1.1600736506845353,0.5471155860670778,0.13563368348203628,0.19958181332532843,0.6060065128039738,0.7026504351173741,-0.08377571033449493,0.4675011541744141,1.6124494198193353,0.027163091494653614,-0.22034471621492466,-0.03909589167063334,-0.38473594847995757,-0.22034471621492466,0.28357365910325655,2.1610865858455655,3.706665868419647,-0.31359071053648363,2.0290981867058675,0.7597604826477616,-0.7574012545226345,0.9089823832894932,-0.10627094673633292,-0.7833273588538234,0.04905067418434559,-0.6804737926663148,2.6592388401689844,1.2296215579874639,-0.8884981438055674,-0.24348703633272678,-0.4569583228314796,1.1249455781236504,-0.24348703633272678,-0.19731314994998111,-1.2766888241918128,1.0181005541038732,3.1648792186751504,0.8349190753908383,-0.6804737926663148,0.8349190753908383,-0.8619817453617755,1.8171233074337798,-0.9961073484547495,0.6642150900524303,1.1775484830852023,0.7217588966997998,0.3456433744169804,-1.6067879521771078,3.739581024322766,-1.023405807478901,1.1949644490190432,-0.24348703633272678,-0.6804737926663148,-0.38473594847995757,0.2627094020641012,4.706308247813215,-0.17439114903384173,1.036063009474167,-0.7833273588538234,0.07084055395748909,0.8349190753908383,0.3865954317326442,-0.8093982448803362,0.816233531485841,1.9392759124745347,-0.9151668939436284,0.7407953762815624,2.5117605953310402,-0.17439114903384173,-0.6804737926663148,-0.2901087935675131,0.6448869477951056,0.3043501904123781,-0.061384384139230704,2.854234483045071,-0.12887118746947637,-0.151577544698465,-0.24348703633272678,-0.17439114903384173,-0.40868858056019347,-0.2901087935675131,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703,0.13563368348203628,1.8016559746006866,0.6834693746272135 3430 Golgi membrane 59 136 4.336110665517773 1.4502594945620118e-05 P35613,Q15392,Q9Y3B3,P24390,O95249,P01889,L0R6Q1,Q9H4A6,Q8IV08,Q9BUR5,Q9H9S5,Q6NTF9,Q14108,O00461,Q8N4A0,P52292,O14617,Q8TBA6,P62820,Q15382,Q16706,Q9UM00,Q9UL01,Q7Z6Z7,Q8TB61,Q9Y287,O95197,Q9BVK6,Q9H7Z7,Q13190,Q7LGA3,Q8NF37,P04439,O43731,Q86Y82,P49755,Q5T9L3,Q10472,O15260,Q7Z3C6,O75063,P53367,P61019,Q8NBN3,Q9Y282,Q6ZRP7,Q14789,P42345,P11166,O60512,Q9P2W9,Q96L58,Q92896,Q8IZA0,Q12907,Q15363,P50570,O43505,O60476 Localization GO Cellular component msigdb_gocc 375,2,133,4,258,507,504,268,273,275,411,541,22,23,153,156,659,286,664,290,554,558,557,667,39,166,42,427,172,301,175,568,684,59,714,315,192,320,319,459,703,209,706,212,85,742,605,354,595,231,107,234,365,237,495,241,491,246,621 504,23,1275,659,2158,816,319,727,1019,246,59,1465,621,231,1784,703,785,42,258,2498,2944,507,684,2346,2049,1210,595,2210,3269,1248,4,1341,375,2397,1748,354,1250,873,874,315,491,1376,156,209,2114,1029,2060,1799,1845,2871,706,789,1346,1641,2304,664,1752,1691,3025,1430,821,320,2013,1298,495,301,1382,22,605,3079,1064,241,290,2,990,554,192,541,742,175,459,667,714,2414,273,237,153,853,2241,212,2129,568,39,286,2132,1447,3140,365,2731,234,1036,1038,2767,1401,275,427,2770,2139,1268,1666,268,172,2325,411,1820,2089,890,1041,1876,107,1360,1933,3086,557,2039,558,969,85,166,1827,2815,2495,1828,133,1122,811 0.6448869477951056,3.9438430597865275,0.07084055395748909,0.4675011541744141,-0.31359071053648363,0.3456433744169804,1.000074973722675,0.406945511095729,0.22071433819033928,1.2811766906485145,3.104102422844003,-0.01690917370953021,0.5074668730496471,1.3995215238872651,-0.151577544698465,0.4272126540305929,0.3661616464083245,3.4479092742401036,1.2296215579874639,-0.4812782346091039,-0.7574012545226345,0.6448869477951056,0.447397619113444,-0.40868858056019347,-0.2667413189986047,0.11413110287400714,0.5273305006198339,-0.3371883420413084,-1.1623836255706177,0.09253370913532158,4.687680585731818,0.04905067418434559,0.8349190753908383,-0.4327622425712757,-0.12887118746947637,0.8905672747951905,0.09253370913532158,0.3043501904123781,0.3043501904123781,1.0181005541038732,0.6642150900524303,0.027163091494653614,1.8632581140200792,1.4988693711510455,-0.2901087935675131,0.22071433819033928,-0.2667413189986047,-0.151577544698465,-0.17439114903384173,-0.7059762210511288,0.4272126540305929,0.3661616464083245,0.04905067418434559,-0.08377571033449493,-0.38473594847995757,0.4675011541744141,-0.12887118746947637,-0.10627094673633292,-0.8093982448803362,0.005176812076117423,0.3456433744169804,1.000074973722675,-0.24348703633272678,0.07084055395748909,0.6642150900524303,1.071800525038966,0.027163091494653614,3.9859536481432736,0.5273305006198339,-0.8619817453617755,0.19958181332532843,1.3491309609547064,1.1249455781236504,4.706308247813215,0.24175657929060165,0.5864529093583782,1.5963727964305452,0.6060065128039738,0.406945511095729,1.692107285757572,0.7026504351173741,0.4675011541744141,0.4272126540305929,-0.4327622425712757,1.1775484830852023,1.382778649014379,1.8937948621783494,0.32503982365867656,-0.3371883420413084,1.482441592729086,-0.2901087935675131,0.5668228264787173,3.482324846985818,1.1425395010761892,-0.2901087935675131,0.005176812076117423,-0.9419899846973533,0.872085387655934,-0.6047865559806115,1.3995215238872651,0.22071433819033928,0.22071433819033928,-0.6298806123677426,0.027163091494653614,1.1775484830852023,0.7597604826477616,-0.6298806123677426,-0.2901087935675131,0.09253370913532158,-0.08377571033449493,1.1949644490190432,1.7236380473068795,-0.38473594847995757,0.7974789711276091,-0.151577544698465,-0.2667413189986047,0.3043501904123781,0.22071433819033928,-0.17439114903384173,2.4019708945127647,0.04905067418434559,-0.19731314994998111,-0.8619817453617755,0.5864529093583782,-0.24348703633272678,0.5864529093583782,0.2627094020641012,2.685636217276718,1.8016559746006866,-0.151577544698465,-0.6551091457204445,-0.4569583228314796,-0.151577544698465,2.1610865858455655,0.17835812614782434,0.3661616464083245 3430 Organelle inner membrane 80 242 4.311011046680496 1.625097859014879e-05 P14406,Q69YU5,Q9H9B4,P17931,Q99720,O43676,Q9H061,Q16134,O60830,P06576,O75964,Q9UBX3,Q99595,Q9Y584,P23786,P03886,Q13505,Q9Y2R0,O75844,O14949,Q9UDW1,Q70HW3,Q9H1E5,Q9UDX5,P22695,Q9H2D1,O14925,Q15070,Q13423,Q9H2V7,Q9P0J0,Q567V2,O43772,O95202,Q8IXM6,O76062,Q9BSK2,Q9Y6C9,P13073,P24539,P12235,Q86Y39,P47985,Q7Z7H8,Q9Y5L4,P00403,P12236,P49748,Q6P4A7,Q8IYU8,Q7KZN9,Q96CU9,Q9Y619,Q9BUR5,Q6DKK2,P21912,Q14739,Q96NB2,Q5XKP0,Q9NPL8,Q99623,Q9NVI7,Q9P032,Q9NUT2,Q96IX5,P14854,Q9BQT8,Q9Y512,Q9Y5J9,Q8NE86,P56385,P04818,Q9Y6M9,Q14197,P22830,P61970,P51970,P05141,Q9UJZ1,Q9BTV4 Localization GO Cellular component msigdb_gocc 9,11,530,523,24,25,26,539,30,536,33,50,56,62,63,74,75,76,81,82,92,97,99,102,106,120,122,126,130,148,149,150,152,154,159,164,165,167,178,183,182,188,191,201,204,213,218,232,247,250,257,263,266,275,280,282,311,352,357,372,383,385,399,398,396,392,409,419,420,425,446,443,482,475,470,472,492,488,520,517 1086,1941,122,82,728,25,2975,152,533,1467,30,623,2387,1206,3093,758,681,2900,2438,2101,2663,1369,81,935,3268,33,2259,164,574,839,3215,154,2620,937,730,978,2293,213,74,443,488,536,2864,1245,1246,2391,2666,1739,3398,182,218,3390,178,9,392,3127,3128,523,2747,3048,2296,2668,282,2790,106,470,1841,63,183,2214,3112,2866,1051,2396,1955,2001,2545,3373,1573,2450,2300,2003,191,3255,3170,232,3362,1172,600,2586,492,2795,1290,686,1423,2912,2588,446,472,2550,820,791,2117,878,2873,792,1177,988,1690,739,2876,1298,2015,1485,1853,130,75,475,3240,565,311,126,539,2837,905,666,991,797,150,2882,906,1105,798,357,11,280,1182,2728,247,585,1307,97,257,2920,201,188,159,250,911,1586,3357,716,3387,1812,425,2070,1352,2606,1763,2075,1074,263,3225,2371,1864,396,352,2032,56,383,24,920,409,634,165,517,3177,275,1189,3032,1551,1357,2140,3000,1981,26,99,120,148,3066,3190,2037,2850,530,2526,2327,2851,2612,2376,372,1403,2574,617,398,3004,1321,385,1322,3107,1987,3037,1721,1011,399,149,50,92,102,1878,1406,967,520,1609,971,1993,76,3229,2255,2935,2616,2858,1726,2816,2155,419,62,2618,420,204,266,167,482 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3430 Envelope 130 493 4.1871830601632585 2.824380192700815e-05 P80303,P55060,Q9NS69,P14406,O43169,Q69YU5,P30536,P45880,Q9P035,Q9H9B4,Q07820,P09601,P21796,Q99720,O43676,Q9H061,Q8N4H5,O60830,Q5BJF2,O75964,Q9UBX3,Q99595,Q9Y584,P23786,P41208,Q86UE4,Q9BXK5,P03886,Q13505,Q9Y2R0,Q8WY22,O75844,O14949,Q96A26,Q9UDW1,Q70HW3,O15118,Q9H1E5,Q9UDX5,Q9BTX1,P22695,O15173,Q9H2D1,O14925,Q15070,Q9NQC3,Q8N2A8,Q13423,Q8NAN2,Q9H2V7,Q9P0J0,Q567V2,O43772,O95202,Q8IXM6,P57105,O76062,Q9BSK2,Q9Y6C9,Q96P70,P13073,P24539,P12235,Q86Y39,P47985,Q8NFQ8,Q7Z7H8,Q9Y5L4,Q96KC8,P00403,O00264,P12236,Q9NZ45,P05067,P49748,Q9NUQ2,P52789,Q9NZJ7,Q6P4A7,Q8IYU8,Q7KZN9,Q96CU9,Q9Y619,Q9H4A6,Q9BUR5,Q6DKK2,P21912,Q96RL7,Q9Y277,P0DP25,Q14739,Q99536,O15397,Q96NB2,Q8TB36,P42345,Q15388,Q5XKP0,Q96AY3,Q07812,Q9NPL8,Q99623,Q6NUM9,Q9NVI7,Q15154,Q9P032,Q9NUT2,Q96IX5,P14854,Q9BQT8,P42167,Q9C0E2,Q9Y512,Q9Y5J9,Q8NE86,O15228,Q9UBM7,Q9BWH2,P56385,P04818,Q9Y6M9,Q14197,P22830,P61970,P57088,Q9BUK6,P51970,P05141,Q9UJZ1,Q9BTV4 Localization GO Cellular component msigdb_gocc 0,510,3,9,10,11,12,13,531,530,525,17,20,24,25,26,29,30,31,33,50,56,62,63,65,70,73,74,75,76,80,81,82,88,92,97,98,99,102,105,106,117,120,122,126,127,132,130,142,148,149,150,152,154,159,162,164,165,167,176,178,183,182,188,191,193,201,204,208,213,216,218,227,224,232,235,236,243,247,250,257,263,266,268,275,280,282,292,294,304,311,316,340,352,351,354,355,357,366,368,372,383,380,385,378,399,398,396,392,409,414,417,419,420,425,421,438,454,446,443,482,475,470,472,493,501,492,488,520,517 1730,1086,216,2859,2257,1367,1941,1943,815,699,1831,3404,2740,3278,1088,122,82,1464,98,117,421,2776,340,10,2258,728,3043,25,2975,152,533,1467,2819,1833,30,623,934,2387,1206,2860,3093,758,681,2900,2438,3313,2101,2388,2663,3180,1369,81,935,3268,33,2259,164,3150,574,839,3215,154,2620,759,937,1788,730,978,2293,1677,213,2978,74,840,2622,443,224,488,536,3252,2864,1090,1245,1246,3235,2391,17,2666,552,1162,304,1739,3398,3413,2210,596,182,218,1837,3390,178,3074,2501,9,392,3127,3128,2536,3280,523,2747,2908,2393,3048,2296,2668,20,282,2790,106,470,1841,63,183,2214,2445,3395,3112,2350,3113,12,2866,1051,1842,2396,1955,2056,1342,2001,2545,3429,3416,3050,3373,1573,65,1095,414,354,2450,564,2300,2003,2219,13,2825,2950,191,3255,3170,2112,232,2547,1958,3362,3270,1172,600,1574,3152,2586,492,3131,236,2795,2224,2587,1290,686,2359,2911,1423,510,2912,2588,446,493,162,2507,472,1378,2550,1529,665,3199,903,0,820,791,2117,878,2873,792,1177,988,2874,1690,3024,1850,739,1963,2876,368,525,1298,3336,1644,2015,766,767,1485,1853,2016,130,75,475,989,3240,3185,768,565,311,3133,3257,126,1698,378,355,3134,539,2066,2837,905,666,991,1701,797,150,31,1490,2882,1913,906,1436,1105,798,3135,3260,357,11,280,2179,1182,380,2728,247,2991,585,742,1183,1307,97,257,2920,2479,1538,201,3059,70,2312,1541,188,1392,2183,1973,1543,159,851,250,1229,911,1585,1310,132,1917,1586,29,2184,3357,142,716,1712,3387,1812,1761,1265,425,1445,193,2070,351,2993,999,2690,2645,1446,1352,2071,80,2605,2606,1661,1662,1763,2073,1398,88,2075,718,366,2847,1074,263,3225,2077,2371,1864,2027,396,208,352,176,2193,292,3287,1038,2998,2032,1817,3318,633,316,831,2137,56,383,24,744,3319,920,409,634,165,517,105,3177,501,275,3427,1770,1455,3365,1928,1040,454,2696,73,745,1189,3032,1551,1357,2140,3000,1664,1981,2570,746,417,26,2485,99,120,148,3066,3190,268,2611,2037,1819,2850,835,530,2526,2327,2851,860,2612,2086,2376,2283,372,1403,2330,127,963,964,2812,2574,617,2331,3,2332,235,2334,398,1010,3004,2424,1321,385,1322,780,3107,1987,3037,1041,1721,227,1324,243,3005,1011,399,531,149,1876,438,2575,50,92,102,1878,2857,1406,838,2427,2970,967,520,3067,1014,1511,3144,1042,1609,294,971,1993,76,3229,2255,2935,973,1828,2616,2858,2041,1726,2816,2381,2155,419,62,3089,2618,420,1728,204,1363,266,167,482 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3430 Vacuole 56 216 4.174949148846081 2.980526231710634e-05 Q07065,P15289,P42858,Q13277,Q15165,Q93050,P06280,Q9UIQ6,Q8IV08,P38435,Q9H2V7,Q14108,Q9BQS8,P11279,Q5BJF2,Q8N511,Q13510,Q9UM22,P42892,Q15382,Q96RL7,P16278,Q14849,Q9H7Z7,Q8NCG7,P42785,P50897,P11117,Q99536,Q16625,P04062,P13473,O15260,Q8WTV0,Q9NQX7,P07602,Q969Q5,P51798,Q8NCC3,Q9Y487,P10253,Q9NX40,O15118,O14678,Q9UHG3,P42345,P17900,Q9BRF8,Q9BTY2,O14773,Q8TBX8,P10619,Q9NZJ7,O75503,Q8NHP8,P54802 Localization GO Cellular component msigdb_gocc 256,374,259,260,8,136,389,143,273,145,148,22,408,413,31,32,158,34,161,290,292,38,43,172,302,47,53,187,316,322,68,196,319,71,203,77,207,335,84,94,349,226,98,222,100,354,104,360,361,110,112,113,243,116,119,124 483,815,699,1560,659,222,110,930,98,319,532,1617,428,1465,1887,932,1621,3266,506,1737,116,534,2104,1676,1677,68,2582,1281,389,1336,2785,2390,1090,77,3011,1161,3372,2164,1415,1470,2346,3217,1948,349,113,187,2295,1282,413,196,374,642,38,3280,104,1567,1475,3333,2109,1520,3395,1476,2167,819,1893,1420,1094,145,3367,2546,2398,354,47,259,161,2301,2505,762,1635,601,53,3022,3152,1684,1685,335,1174,1637,1480,2359,124,2716,1799,1845,706,1346,1846,2360,1482,3317,2677,2401,1530,950,903,1531,1428,1294,2831,649,3056,2460,256,2266,2636,2013,1645,1965,1431,260,158,2232,2175,22,794,768,43,415,8,290,322,31,881,1108,459,273,1393,654,32,2762,84,302,568,2959,119,3286,112,71,1446,2604,717,615,136,207,1231,3206,1188,1816,546,569,3176,2483,292,2423,2522,633,316,1452,2693,3319,408,360,480,361,3427,1504,2139,3210,1665,1150,1008,1320,148,172,3249,203,2967,1875,226,2092,243,3005,1876,1989,1270,1824,100,2491,143,2253,34,1014,2288,1121,1938,3166,784,1828,94,2341,2382,639,698,1201,1777,1778 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3430 Ion transmembrane transport 64 154 4.141143868436935 3.455781097794208e-05 Q13546,P42858,P53985,Q13423,Q9NUT2,O60831,Q9HD20,Q9Y619,P55011,Q9H9B4,P45880,P14854,P46934,P21796,Q9BQT8,P20020,O43772,O95202,P06576,Q15043,O75964,Q9UM00,Q9Y277,Q15041,Q8TB61,Q8NE86,Q9C0H2,P0DP25,Q9UBX3,P13073,Q96GC9,Q14728,P08183,P24539,Q96ES6,P12235,Q6YHU6,P47985,P56385,Q00535,Q9P2D1,Q4KMQ2,O75844,P51798,P00403,P12236,Q9UDW1,Q96NB2,P30825,Q99623,Q70HW3,P05067,Q9UHG3,P78417,Q07812,P50570,O43808,Q9UJZ1,P05141,Q6P4A7,Q9H2D1,P16615,Q8IYU8,Q7KZN9 Processes and pathways GO Biological process msigdb_gobp 512,259,509,130,398,505,137,266,394,530,13,392,524,20,409,278,152,154,536,415,33,558,294,424,39,425,45,304,50,178,569,565,429,183,57,182,586,191,446,582,339,608,81,335,213,218,92,352,225,383,97,224,100,103,368,491,486,520,488,247,120,249,250,257 2859,2738,1941,1996,152,486,702,2437,505,623,2941,2387,2860,2900,1369,81,817,3268,33,154,937,213,897,224,488,2665,536,3234,2785,2390,3372,429,2164,1245,2049,304,1739,3236,182,218,178,392,249,1247,2536,2746,2667,278,2296,1475,3333,3219,20,1049,183,2214,1520,2710,3113,3076,225,1051,3348,2001,1094,2546,259,13,524,1374,191,3255,491,335,1290,509,1058,2170,394,2588,446,2360,2012,1031,103,1690,582,739,2229,1252,368,2636,1645,130,512,1802,2233,565,2986,1909,424,415,1064,1699,608,247,1107,586,97,257,1393,3383,250,997,425,39,1352,802,57,569,2997,352,1594,3318,383,1502,409,1770,1006,45,1150,120,2144,2850,530,137,924,398,339,50,92,1933,100,2491,967,520,558,294,1327,2431,2155,266,3330,619 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3430 Cognitive impairment 46 176 4.031939686779531 5.531838549255319e-05 P15289,P42858,Q9Y619,P14854,Q9BQE5,P06280,Q9H9S5,Q13426,Q14108,Q99720,Q6DKK2,P21912,Q13510,Q96RL7,P16278,Q9Y287,O95613,Q6PGP7,P49770,P50897,O43681,P12235,O95470,P21964,P04062,P13473,P03886,Q9Y2R0,P07602,Q13315,O76024,P00403,Q9Y487,P05067,O15118,P42345,Q13535,Q5XKP0,P17900,P27544,Q9NZJ7,O75503,Q03164,Q9NPL8,Q9NZ08,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,259,266,392,15,389,411,21,22,24,280,282,158,292,38,166,423,307,432,53,428,182,64,445,68,196,74,76,77,332,455,213,94,224,98,354,230,357,104,239,243,116,244,372,386,124 1367,1329,98,428,533,1467,2344,506,1206,549,116,593,455,2440,64,423,730,2293,213,507,74,68,1678,704,2784,224,389,1336,2047,77,3011,1414,1370,2786,3323,1740,595,182,196,392,374,38,1793,104,787,1474,2668,3219,1418,282,445,2109,2395,734,239,2866,871,2868,1168,1094,2546,842,354,2450,259,2002,2300,1028,2949,471,2712,432,1479,53,2951,2714,1524,2302,843,124,1423,2716,1526,2507,1175,2012,1482,1897,1531,1532,649,244,951,2172,3056,1252,1298,3396,767,1534,2985,1431,332,21,158,230,22,989,1854,1855,2469,2834,2758,1700,2177,3186,357,280,2919,307,1535,2411,3081,1183,1858,1442,1229,2184,1977,2645,613,2320,2807,2567,2846,2418,2420,2483,292,856,776,1925,3318,2849,24,15,3177,1818,3289,411,372,2735,1404,696,2968,386,243,1117,927,1153,1407,967,3040,1991,2380,1016,166,76,1326,865,94,1994,2155,1727,591,266 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3430 Vacuolar lumen 23 66 4.00037055160742 6.32433751257544e-05 P15289,Q8IV08,P38435,Q14108,Q13510,Q9UM22,P16278,Q9H7Z7,P50897,P11117,Q99536,P04062,P13473,P07602,P10253,Q9BRF8,P17900,Q9BTY2,O14773,P10619,Q9NZJ7,Q8NHP8,P54802 Localization GO Cellular component msigdb_gocc 374,273,145,22,158,34,38,172,53,187,316,68,196,77,349,360,104,361,110,113,243,119,124 815,699,1560,110,428,1677,68,2582,389,1336,2785,1090,77,3011,1161,1415,349,113,187,2295,1282,196,374,642,38,104,1476,2167,145,3367,762,1635,53,3022,1637,2359,124,2716,1846,1482,1530,950,1294,2831,2460,1431,158,22,794,273,2762,119,615,1188,2423,2522,316,360,361,1504,172,2092,243,34,1938,1201 0.3456433744169804,0.4272126540305929,-0.061384384139230704,2.360226918485896,0.7407953762815624,-0.10627094673633292,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,-0.6551091457204445,0.17835812614782434,2.8157767839559593,-0.8093982448803362,0.13563368348203628,0.005176812076117423,0.9089823832894932,2.3322196827838484,1.6124494198193353,-0.38473594847995757,0.07084055395748909,1.5640718300941014,0.8349190753908383,0.487523996503178,3.5165359909007803,2.4571398271524862,-0.01690917370953021,-0.31359071053648363,2.0142315842992913,-1.4839299067547875,0.3865954317326442,-0.08377571033449493,3.2250123758744826,-0.8093982448803362,-0.08377571033449493,-0.40868858056019347,2.2187310778900433,-0.6047865559806115,-0.17439114903384173,-0.01690917370953021,-0.03909589167063334,0.2627094020641012,0.07084055395748909,-0.6804737926663148,-0.4569583228314796,0.005176812076117423,1.8479240879335823,3.9859536481432736,0.3661616464083245,1.1775484830852023,-0.6298806123677426,2.2757707336590367,0.5273305006198339,0.13563368348203628,-0.4327622425712757,-0.4812782346091039,1.0181005541038732,0.8905672747951905,0.8905672747951905,-0.01690917370953021,1.7236380473068795,-0.2667413189986047,1.3322253587909487,3.5618375403217266,-0.19731314994998111,0.13563368348203628 3430 Ion transmembrane transporter activity 49 95 3.970418312721257 7.174655226904747e-05 P53985,Q13423,Q93050,Q9HD20,Q9Y619,P55011,Q9H9B4,P45880,P14854,P21796,Q9BQT8,P20020,O43772,O95202,P06576,Q15043,O75964,Q9UM00,Q9Y277,Q8NE86,Q8TB61,Q9C0H2,Q9UBX3,P13073,Q14728,P24539,Q96ES6,P12235,O43681,P47985,P56385,Q00535,Q4KMQ2,P51798,P00403,P12236,Q9UDW1,Q9Y6M7,Q9Y487,P30825,Q96NB2,Q70HW3,P11166,O43808,P05141,Q6P4A7,Q9H2D1,P16615,Q7KZN9 Functions GO Molecular function msigdb_gomf 509,130,136,137,266,394,530,13,392,20,409,278,152,154,536,415,33,558,294,425,39,45,50,178,565,183,57,182,428,191,446,582,608,335,213,218,92,619,94,225,352,97,595,486,488,247,120,249,257 2859,428,152,486,1369,3268,33,154,937,213,897,488,536,3234,2785,3372,2164,1245,2049,1739,595,182,218,178,392,249,278,2296,1475,3333,20,1049,183,2214,225,1051,2001,1094,2546,13,191,3255,335,1290,509,394,2588,446,2360,2012,1690,582,739,130,565,2986,415,1699,608,3368,1182,3187,247,1107,97,257,1393,425,39,802,136,57,352,1038,2963,409,1770,1006,45,1150,120,2850,530,137,50,92,2491,967,558,294,94,639,266,3330,619 -0.7059762210511288,0.7407953762815624,1.8937948621783494,0.6642150900524303,0.027163091494653614,-1.1623836255706177,3.5731076371518076,1.8785482781004688,0.2627094020641012,1.4659622290827485,0.28357365910325655,0.6642150900524303,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-1.5143297421023834,-0.31359071053648363,0.09253370913532158,-0.2667413189986047,-0.12887118746947637,0.5273305006198339,1.6444566286616846,1.4494309133701686,1.6603878760836814,0.816233531485841,1.2640484788395443,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,3.9859536481432736,0.19958181332532843,1.6444566286616846,-0.3371883420413084,1.4328472746723286,0.19958181332532843,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,4.222429217331235,1.5963727964305452,-1.1342490728645735,0.945614424806558,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.24348703633272678,-0.10627094673633292,0.5471155860670778,0.406945511095729,2.1610865858455655,0.5668228264787173,-0.7833273588538234,0.7786548166059916,-0.10627094673633292,0.5273305006198339,-1.4839299067547875,0.13563368348203628,-1.023405807478901,1.2811766906485145,0.17835812614782434,2.552373754198136,1.2468635762934643,0.027163091494653614,0.7597604826477616,3.482324846985818,0.3661616464083245,2.1174474931929272,3.1527758461637907,0.9089823832894932,0.22071433819033928,-0.7574012545226345,0.7974789711276091,-0.12887118746947637,0.24175657929060165,3.3784536775429674,0.15704238472925763,2.2615667415404976,-0.6804737926663148,0.6254843056815558,2.1028225946561765,3.2845170686821423,2.6194057651180533,-0.4569583228314796,0.2627094020641012,0.5864529093583782,1.107291420206707,2.6060641851362782,0.5074668730496471,1.2123219939175685,-1.3057195477388794,0.5273305006198339 3430 Lysosome 23 50 3.888330541960108 0.0001009361048358 P15289,Q93050,P06280,Q14108,P11279,Q13510,P16278,Q15904,P50897,P11117,P04062,P13473,P07602,Q8NCC3,Q9Y487,P10253,O15118,P17900,O14773,P10619,Q9NZJ7,O75503,P54802 Processes and pathways KEGG Pathways msigdb_kegg 374,136,389,22,413,158,38,434,53,187,68,196,77,84,94,349,98,104,110,113,243,116,124 483,1560,659,110,98,428,1465,116,68,2582,389,1336,77,3011,1415,3217,3151,349,113,187,413,2210,196,374,642,38,104,1567,3367,53,124,2360,1482,1531,2013,158,22,434,84,801,136,2522,633,2139,243,2491,1462,2530,784,94 0.6642150900524303,-0.061384384139230704,0.4675011541744141,2.360226918485896,2.5388692262913795,0.7407953762815624,-0.01690917370953021,2.3181620708424706,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,2.8157767839559593,-0.8093982448803362,0.005176812076117423,-1.0784930750204527,-0.9689694457036316,0.9089823832894932,2.3322196827838484,1.6124494198193353,0.7786548166059916,-0.3371883420413084,1.5640718300941014,0.8349190753908383,0.487523996503178,3.5165359909007803,2.4571398271524862,-0.061384384139230704,-1.4839299067547875,3.2250123758744826,2.2187310778900433,-0.40868858056019347,-0.01690917370953021,-0.03909589167063334,-0.24348703633272678,1.8479240879335823,3.9859536481432736,0.7407953762815624,2.6987880108067723,0.3661616464083245,2.1174474931929272,-0.4812782346091039,0.5074668730496471,-0.2901087935675131,1.3322253587909487,-0.4569583228314796,0.005176812076117423,-0.4812782346091039,0.3865954317326442,2.6060641851362782 3430 Anion transport 33 67 3.854075204809468 0.0001161678866721 Q13546,P53985,O60831,P55011,Q9Y619,Q9H9B4,P30536,P45880,P21796,Q9BQT8,Q15043,Q15041,Q9Y277,Q8TB61,Q9C0H2,Q9UBX3,Q14728,P08183,O43681,P12235,P07602,Q4KMQ2,P51798,P12236,Q96NB2,Q9Y6M7,P30825,Q9UHG3,Q15907,O43808,Q9NZJ7,P05141,Q9H2D1 Processes and pathways GO Biological process msigdb_gobp 512,509,505,394,266,530,12,13,20,409,415,424,294,39,45,50,565,429,428,182,77,608,335,218,352,619,225,100,111,486,243,488,120 2859,428,486,702,505,1369,817,937,1890,488,2665,77,429,2164,2049,595,182,218,1518,1418,20,1286,12,225,13,335,1290,509,901,394,1902,1690,739,512,565,424,710,415,1699,111,608,3368,1182,3187,1393,39,352,1038,2963,409,1006,45,2033,120,2850,530,2086,243,50,100,1119,967,294,2431,266,3330,619 -0.7059762210511288,0.7407953762815624,0.6642150900524303,0.4272126540305929,0.6448869477951056,0.027163091494653614,0.3456433744169804,0.2627094020641012,-0.19731314994998111,0.6642150900524303,-0.5798253703616462,2.8157767839559593,0.7407953762815624,-0.31359071053648363,-0.2667413189986047,0.5273305006198339,1.6444566286616846,1.4494309133701686,-0.03909589167063334,0.005176812076117423,3.9859536481432736,0.07084055395748909,4.222429217331235,1.4328472746723286,4.222429217331235,0.945614424806558,0.07084055395748909,0.6448869477951056,0.28357365910325655,0.816233531485841,-0.19731314994998111,-0.10627094673633292,0.406945511095729,0.6448869477951056,0.5668228264787173,0.7597604826477616,0.4272126540305929,0.7786548166059916,-0.10627094673633292,2.34624122931555,0.5273305006198339,-1.4839299067547875,0.13563368348203628,-1.023405807478901,0.027163091494653614,3.482324846985818,0.9089823832894932,0.22071433819033928,-0.7574012545226345,0.7974789711276091,0.24175657929060165,3.3784536775429674,-0.24348703633272678,2.2615667415404976,-0.6804737926663148,0.6254843056815558,-0.2667413189986047,1.3322253587909487,3.2845170686821423,2.5388692262913795,0.17835812614782434,0.2627094020641012,1.107291420206707,-0.4327622425712757,1.2123219939175685,-1.3057195477388794,0.5273305006198339 3430 Anion transmembrane transport 25 40 3.8537731676286575 0.0001163113598763 Q13546,P53985,O60831,P55011,Q9Y619,Q9H9B4,P45880,P21796,Q9BQT8,Q15041,Q9Y277,Q8TB61,Q9UBX3,Q14728,P08183,P12235,Q4KMQ2,P51798,P12236,Q96NB2,P30825,Q9UHG3,O43808,P05141,Q9H2D1 Processes and pathways GO Biological process msigdb_gobp 512,509,505,394,266,530,13,20,409,424,294,39,50,565,429,182,608,335,218,352,225,100,486,488,120 486,505,1369,817,937,488,2665,429,2164,182,218,20,225,13,335,1290,509,394,1690,739,512,565,424,1699,608,1393,39,352,409,1006,120,2850,530,50,100,967,294,2431,266,619 0.6642150900524303,0.6448869477951056,0.027163091494653614,0.3456433744169804,0.2627094020641012,0.6642150900524303,-0.5798253703616462,0.7407953762815624,-0.31359071053648363,1.6444566286616846,1.4494309133701686,3.9859536481432736,1.4328472746723286,4.222429217331235,0.945614424806558,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.10627094673633292,0.406945511095729,0.6448869477951056,0.5668228264787173,0.7597604826477616,-0.10627094673633292,0.5273305006198339,0.027163091494653614,3.482324846985818,0.9089823832894932,0.7974789711276091,0.24175657929060165,2.2615667415404976,-0.6804737926663148,0.6254843056815558,3.2845170686821423,2.5388692262913795,0.2627094020641012,1.107291420206707,-0.4327622425712757,1.2123219939175685,0.5273305006198339 3430 Lysosomal lumen 20 36 3.820429473216734 0.0001332194963437 P15289,P06280,Q8IV08,P38435,Q14108,Q13510,Q9UM22,P16278,P50897,P11117,P04062,P13473,P07602,P10253,P17900,O14773,P10619,Q9NZJ7,Q8NHP8,P54802 Localization GO Cellular component msigdb_gocc 374,389,273,145,22,158,34,38,53,187,68,196,77,349,104,110,113,243,119,124 699,1560,110,428,68,2582,389,1336,77,3011,1161,1415,349,113,187,2295,196,374,642,38,104,145,3367,762,53,124,1482,158,22,273,2762,119,2522,1504,243,34 0.4272126540305929,-0.061384384139230704,2.360226918485896,0.7407953762815624,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,2.8157767839559593,-0.8093982448803362,0.13563368348203628,0.005176812076117423,0.9089823832894932,2.3322196827838484,1.6124494198193353,-0.38473594847995757,1.5640718300941014,0.8349190753908383,0.487523996503178,3.5165359909007803,2.4571398271524862,2.0142315842992913,-1.4839299067547875,0.3865954317326442,3.2250123758744826,2.2187310778900433,-0.01690917370953021,1.8479240879335823,3.9859536481432736,1.1775484830852023,-0.6298806123677426,2.2757707336590367,-0.4812782346091039,-0.01690917370953021,1.3322253587909487,3.5618375403217266 3430 Metabolism of lipids 61 200 3.757750696887952 0.000171447566384 Q6IAN0,P54646,Q15392,Q8N2A8,P15289,Q15165,P30536,Q8NAN2,Q14534,Q16850,P38435,Q8IV08,P06280,O95864,O43772,O75448,Q13510,O76062,P16278,Q9NPH0,Q9Y6B6,Q14849,Q9H7Z7,O15228,A8MXV4,Q06520,Q9UBM7,P50897,P48449,P48651,Q14739,O43681,Q96G23,Q96N66,P23786,O95470,Q9BXW6,P04062,O15269,Q53GQ0,P07602,O00116,P51648,Q8NCC3,Q9BTU6,Q06136,O75845,Q15067,P49327,Q16836,Q15800,P17900,P49748,Q9NUQ2,Q8TBX8,P10619,P27544,Q9NZJ7,O00767,O43808,P37268 Processes and pathways Reactome Pathways msigdb_reactome 514,254,2,132,374,8,12,142,272,146,145,273,389,388,152,401,158,164,38,40,300,43,172,421,46,174,438,53,184,431,311,428,61,451,63,64,324,68,441,202,77,205,79,84,480,87,468,350,471,356,101,104,232,235,112,113,239,243,484,486,123 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3430 Ion transport 76 210 3.7153254762659897 0.000202942298461 Q13546,P42858,P53985,Q13423,Q9NUT2,O60831,Q9HD20,Q9Y619,P55011,Q9H9B4,P45880,P30536,P14854,P46934,P17931,P21796,Q9BQT8,P20020,O43772,O95202,P06576,Q15043,O75964,Q9UM00,Q9Y277,Q15041,Q8TB61,Q8NE86,Q9C0H2,P0DP25,Q9UBX3,P13073,Q96GC9,Q14728,P08183,P24539,Q96ES6,P20337,P12235,O43681,Q9UJZ1,Q6YHU6,P47985,P56385,P07602,Q99959,Q00535,Q9P2D1,Q4KMQ2,O75844,P51798,O76024,P00403,P12236,Q9Y6M7,Q9UDW1,P30825,Q96NB2,Q99623,Q70HW3,P05067,Q9UHG3,P78417,Q15907,Q07812,P50570,Q9NZJ7,O43808,O15173,P05141,Q6P4A7,Q9H2D1,P16615,Q8IYU8,Q8NE01,Q7KZN9 Processes and pathways GO Biological process msigdb_gobp 512,259,509,130,398,505,137,266,394,530,13,12,392,524,523,20,409,278,152,154,536,415,33,558,294,424,39,425,45,304,50,178,569,565,429,183,57,562,182,428,520,586,191,446,77,333,582,339,608,81,335,455,213,218,619,92,225,352,383,97,224,100,103,111,368,491,243,486,117,488,247,120,249,250,381,257 2859,2738,1367,1941,2740,1158,117,428,1996,152,486,702,2437,505,623,2941,2387,2860,2160,2900,1369,81,817,3268,33,455,154,1125,937,2293,213,732,1890,2707,897,224,488,2665,1335,536,3234,2785,2390,77,3372,429,2164,1245,2049,304,1739,595,2441,3236,182,218,178,2211,1518,2501,392,249,1247,2536,2746,523,2667,278,562,2296,1475,3333,3219,1418,20,1049,183,1419,2214,1520,2710,1286,3113,12,3076,225,1051,1571,1420,2542,3348,2001,1094,2546,259,13,2505,524,1374,191,3255,491,335,1174,1290,509,901,1058,2170,394,2588,446,1100,2360,2798,2012,1031,103,1902,1690,582,1531,2228,739,2229,1252,368,1429,2636,1645,130,512,1138,1802,2233,565,2986,1909,424,710,415,1064,1699,111,905,608,3368,1182,3187,247,1107,586,97,257,1393,3383,250,997,381,425,39,1352,802,57,569,2997,352,1594,1038,3318,383,2963,333,1502,409,1770,1006,45,2033,1150,120,2144,2850,530,137,924,2086,3428,398,243,339,50,92,1933,100,1119,2491,967,520,2615,558,2040,1608,294,1327,2431,2155,266,3330,619 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3430 Outer membrane 34 93 3.678684180929018 0.0002344403588696 Q8N2A8,Q9NS69,O43169,P30536,P45880,Q8NAN2,P09601,Q9BUR5,P21796,Q99720,Q8N4H5,P57105,Q9Y512,Q96RL7,Q9Y277,Q9Y6C9,Q9UBM7,Q9BWH2,Q99536,Q13505,Q8WY22,O00264,Q8TB36,Q9NZ45,P42345,Q15388,P61970,Q5XKP0,Q9NUQ2,P52789,Q07812,Q9NZJ7,Q99623,Q6NUM9 Localization GO Cellular component msigdb_gocc 132,3,10,12,13,142,17,275,20,24,29,162,419,292,294,167,438,454,316,75,80,216,351,227,354,355,472,357,235,236,368,243,383,380 216,1367,3404,10,1467,1833,2860,758,3150,1788,2293,1677,840,3252,2391,17,2393,20,12,1842,3416,3373,354,2450,13,600,1574,236,2912,162,472,368,525,767,75,1698,355,3134,666,797,3260,357,380,2991,585,1183,1538,1392,1973,1543,1229,132,29,2184,142,1712,351,2071,80,2073,1398,2077,2027,292,1817,316,383,24,501,275,1770,454,2696,745,835,2330,963,2331,3,235,2424,1321,780,3037,1041,227,243,438,2857,294,1828,419,167 1.4494309133701686,0.027163091494653614,-2.0313624559825123,4.3124581612681805,-0.01690917370953021,-0.17439114903384173,-0.7059762210511288,0.3865954317326442,-0.9689694457036316,-0.151577544698465,-0.38473594847995757,-0.10627094673633292,0.32503982365867656,-1.1342490728645735,-0.4327622425712757,4.05893051652828,-0.4327622425712757,3.9859536481432736,4.222429217331235,-0.17439114903384173,-2.5764377108191203,-1.5449371974827035,0.8905672747951905,-0.4569583228314796,4.222429217331235,0.5273305006198339,-0.061384384139230704,1.382778649014379,-0.7316181307528602,1.8325459149864132,0.6834693746272135,0.8535361731217637,0.6254843056815558,0.3865954317326442,2.854234483045071,-0.10627094673633292,0.8905672747951905,-0.9419899846973533,0.4675011541744141,0.3661616464083245,-1.1342490728645735,0.8905672747951905,0.8349190753908383,-0.7833273588538234,0.5471155860670778,0.13563368348203628,-0.03909589167063334,0.027163091494653614,-0.22034471621492466,-0.03909589167063334,0.11413110287400714,2.1610865858455655,3.706665868419647,-0.31359071053648363,2.0290981867058675,-0.10627094673633292,0.9089823832894932,-0.2667413189986047,2.7640846335071103,-0.2667413189986047,0.027163091494653614,-0.2667413189986047,-0.24348703633272678,1.1249455781236504,-0.151577544698465,1.0181005541038732,0.8349190753908383,3.8907768973797325,0.6642150900524303,1.1775484830852023,-0.12887118746947637,0.7217588966997998,-0.5798253703616462,0.406945511095729,0.3456433744169804,-0.38473594847995757,0.2627094020641012,-0.38473594847995757,4.706308247813215,1.3995215238872651,-0.4327622425712757,0.07084055395748909,0.3865954317326442,-0.8093982448803362,0.22071433819033928,1.4328472746723286,1.3322253587909487,0.7407953762815624,-0.6804737926663148,1.107291420206707,-0.151577544698465,0.7786548166059916,1.8016559746006866 3430 Sphingolipid metabolism 15 26 3.5780949903728376 0.0003461076725135 Q13510,P15289,O95470,P04062,P16278,P17900,P07602,P06280,P51648,P27544,P10619,Q9NZJ7,Q06136,O43681,Q96G23 Processes and pathways Reactome Pathways msigdb_reactome 158,374,64,68,38,104,77,389,79,239,113,243,87,428,61 1241,441,1673,428,1889,64,68,389,1336,77,3011,113,374,38,104,1248,239,79,87,158,61,2522,2524,1041,243,1876 0.09253370913532158,0.7217588966997998,-0.10627094673633292,0.7407953762815624,-0.19731314994998111,3.0426662360183325,2.993031551841918,0.816233531485841,0.04905067418434559,2.8157767839559593,-0.8093982448803362,2.3322196827838484,0.8349190753908383,3.5165359909007803,2.4571398271524862,0.09253370913532158,1.3491309609547064,2.777052623692763,2.672453216244307,1.8479240879335823,3.104102422844003,-0.4812782346091039,-0.4812782346091039,0.22071433819033928,1.3322253587909487,-0.17439114903384173 3430 Membrane lipid metabolic process 14 37 3.5685169884074965 0.0003590075791022 Q13510,O95470,P04062,P16278,Q8NBX0,O60512,P17900,P07602,O43292,P27544,Q8NCC3,P50897,Q06136,Q96G23 Processes and pathways GO Biological process msigdb_gobp 158,64,68,38,135,231,104,77,177,239,84,53,87,61 441,1673,177,231,1998,64,68,2582,389,1336,77,3011,38,104,1248,239,2261,53,2460,87,368,158,797,135,84,588,2188,61,3244,2522,744,834,1041,676,243,531,1876 0.7217588966997998,-0.10627094673633292,1.6603878760836814,1.3995215238872651,-0.24348703633272678,3.0426662360183325,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,2.8157767839559593,-0.8093982448803362,3.5165359909007803,2.4571398271524862,0.09253370913532158,1.3491309609547064,-0.36090298236806184,3.2250123758744826,-0.4569583228314796,2.672453216244307,0.8535361731217637,1.8479240879335823,0.3661616464083245,2.1320329656479697,2.6987880108067723,0.5471155860670778,-0.31359071053648363,3.104102422844003,-1.1062863390031978,-0.4812782346091039,0.406945511095729,0.3456433744169804,0.22071433819033928,0.4675011541744141,1.3322253587909487,0.6254843056815558,-0.17439114903384173 3430 Sphingolipid metabolic process 15 28 3.528775596271673 0.000417486985156 Q13510,O95470,P04062,P16278,O60512,P17900,P07602,P06280,Q07812,P27544,Q9NZJ7,Q8NCC3,P50897,Q06136,Q96G23 Processes and pathways GO Biological process msigdb_gobp 158,64,68,38,231,104,77,389,368,239,243,84,53,87,61 441,1673,231,64,68,389,1336,77,3011,38,104,1248,239,2261,53,2460,87,368,158,797,84,61,2522,1041,676,243,531,1876 0.7217588966997998,-0.10627094673633292,1.3995215238872651,3.0426662360183325,2.993031551841918,0.816233531485841,0.04905067418434559,2.8157767839559593,-0.8093982448803362,3.5165359909007803,2.4571398271524862,0.09253370913532158,1.3491309609547064,-0.36090298236806184,3.2250123758744826,-0.4569583228314796,2.672453216244307,0.8535361731217637,1.8479240879335823,0.3661616464083245,2.6987880108067723,3.104102422844003,-0.4812782346091039,0.22071433819033928,0.4675011541744141,1.3322253587909487,0.6254843056815558,-0.17439114903384173 3430 Mitochondrial transport 26 85 3.520854101377344 0.0004301592264195 P55786,Q9NS69,P30536,P45880,Q9P0J0,O43772,Q8N4H5,O60830,O75964,Q9Y512,Q14849,Q9UBX3,P24539,Q99595,P12235,Q9Y584,P23786,O14737,Q9Y5L4,Q8TB36,Q15388,P52789,Q07812,Q99797,O14925,Q15070 Processes and pathways GO Biological process msigdb_gobp 128,3,12,13,149,152,29,30,33,419,43,50,183,56,182,62,63,329,204,351,355,236,368,384,122,126 1995,329,122,728,152,30,1368,758,2900,3268,33,3150,2820,3295,3193,730,2293,2784,488,536,1161,2391,3398,182,1630,63,183,2214,3113,2215,12,2867,2001,3019,13,3255,1682,874,2009,1574,1376,236,128,2588,446,1426,368,1298,43,126,355,3134,991,797,609,1182,667,1973,1543,29,351,1352,631,2483,1925,56,384,833,2851,2574,3,149,3123,50,2149,967,520,1609,1828,419,62,2618,420,204,1201 -0.24348703633272678,0.9638324211451322,2.233047134387105,0.406945511095729,1.8937948621783494,3.684618516209035,0.027163091494653614,0.3865954317326442,-0.7316181307528602,-1.1623836255706177,3.5731076371518076,-0.9689694457036316,-0.6804737926663148,-1.2191778402877913,-1.0508669815631295,0.406945511095729,-0.38473594847995757,-0.6551091457204445,0.6642150900524303,0.6060065128039738,0.13563368348203628,-0.4327622425712757,-1.7976755345030844,1.6444566286616846,-0.08377571033449493,3.0673208707632353,1.6444566286616846,-0.3371883420413084,-0.9151668939436284,-0.3371883420413084,4.222429217331235,-0.7059762210511288,-0.24348703633272678,-0.8093982448803362,4.222429217331235,-1.1342490728645735,-0.10627094673633292,0.3043501904123781,-0.24348703633272678,-0.061384384139230704,0.027163091494653614,1.382778649014379,2.1755552047661753,-0.5302953342350691,0.7217588966997998,0.005176812076117423,0.8535361731217637,0.07084055395748909,3.413286496271575,2.1899853400179143,0.8905672747951905,-0.9419899846973533,0.24175657929060165,0.3661616464083245,0.5273305006198339,0.13563368348203628,0.4675011541744141,-0.22034471621492466,-0.03909589167063334,3.706665868419647,0.9089823832894932,0.04905067418434559,0.5074668730496471,-0.4569583228314796,-0.19731314994998111,3.1648792186751504,0.8349190753908383,0.3456433744169804,-0.6804737926663148,-0.5057234167351391,4.706308247813215,1.9392759124745347,-0.9151668939436284,3.2845170686821423,-0.2901087935675131,0.2627094020641012,0.6448869477951056,-0.061384384139230704,-0.151577544698465,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703,0.13563368348203628 3430 Inorganic molecular entity transmembrane transporter activity 35 71 3.514847518099686 0.0004400065524319 Q13423,Q93050,Q9HD20,P55011,P14854,P45880,P21796,P20020,O95202,P06576,Q15043,O75964,Q9UM00,Q9Y277,Q8NE86,Q9C0H2,P13073,Q9UBX3,O43681,P24539,P12235,Q96ES6,P47985,P56385,Q00535,Q4KMQ2,P51798,P00403,Q9UDW1,Q9Y487,Q9Y6M7,P05141,Q99797,P16615,Q7KZN9 Functions GO Molecular function msigdb_gomf 130,136,137,394,392,13,20,278,154,536,415,33,558,294,425,45,178,50,428,183,182,57,191,446,582,608,335,213,92,94,619,488,384,249,257 2859,428,3268,33,154,213,897,488,536,3234,2785,3372,2164,1245,2049,1739,182,178,392,249,278,2296,1475,3333,20,1049,183,2214,1051,2001,1094,2546,13,191,3255,335,394,2588,446,2360,2012,1690,582,739,130,415,608,3368,1107,257,1393,425,802,136,57,1038,384,1006,45,1150,2850,137,50,92,2491,558,294,94,639,3330,619 -0.7059762210511288,0.7407953762815624,-1.1623836255706177,3.5731076371518076,1.8785482781004688,1.4659622290827485,0.28357365910325655,0.6642150900524303,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-1.5143297421023834,-0.31359071053648363,0.09253370913532158,-0.2667413189986047,-0.12887118746947637,1.6444566286616846,1.6603878760836814,0.816233531485841,1.2640484788395443,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,3.9859536481432736,0.19958181332532843,1.6444566286616846,-0.3371883420413084,0.19958181332532843,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,4.222429217331235,1.5963727964305452,-1.1342490728645735,0.945614424806558,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.24348703633272678,-0.10627094673633292,0.5471155860670778,0.406945511095729,2.1610865858455655,0.7786548166059916,0.5273305006198339,-1.4839299067547875,0.17835812614782434,1.2468635762934643,0.027163091494653614,0.7597604826477616,0.3661616464083245,2.1174474931929272,3.1527758461637907,0.22071433819033928,0.8349190753908383,0.24175657929060165,3.3784536775429674,0.15704238472925763,-0.6804737926663148,2.1028225946561765,3.2845170686821423,2.6194057651180533,-0.4569583228314796,0.5864529093583782,1.107291420206707,2.6060641851362782,0.5074668730496471,-1.3057195477388794,0.5273305006198339 3430 SLC superfamily of solute carriers 22 41 3.469994747150431 0.0005204685435187 P53985,P55011,Q9Y619,Q9H2V7,Q9BQT8,O43772,O95202,Q15043,Q9BSK2,Q9Y6C9,Q8TB61,Q9UBX3,Q8IXU6,P12235,P12236,Q96NB2,P30825,Q70HW3,O43808,Q9NZJ7,P05141,Q9H2D1 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 509,394,266,148,409,152,154,415,165,167,39,50,179,182,218,352,225,97,486,243,488,120 678,152,486,1369,154,937,488,2164,595,182,218,225,1290,509,394,1690,739,415,1699,3368,1182,3187,97,179,39,352,2963,409,165,1006,1150,120,148,2850,530,243,50,967,266,167,619 0.447397619113444,1.8937948621783494,0.6642150900524303,0.027163091494653614,1.8785482781004688,0.2627094020641012,0.6642150900524303,-0.31359071053648363,0.5273305006198339,1.6444566286616846,1.4494309133701686,1.4328472746723286,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.10627094673633292,0.406945511095729,0.7786548166059916,-0.10627094673633292,-1.4839299067547875,0.13563368348203628,-1.023405807478901,2.552373754198136,1.6603878760836814,3.482324846985818,0.9089823832894932,-0.7574012545226345,0.7974789711276091,1.8171233074337798,0.24175657929060165,0.15704238472925763,2.2615667415404976,1.9392759124745347,-0.6804737926663148,0.6254843056815558,1.3322253587909487,3.2845170686821423,0.2627094020641012,1.2123219939175685,1.8016559746006866,0.5273305006198339 3430 Steroid metabolic process 23 71 3.464969285705618 0.0005302920392391 P54646,Q15392,P30536,Q9BQE5,Q14534,Q16850,P38435,Q13510,O76062,Q14849,Q06520,P48449,P16435,Q14739,O95470,P04062,Q8WTV0,Q53GQ0,P05067,O15118,Q15800,P49748,P37268 Processes and pathways GO Biological process msigdb_gobp 254,2,12,15,272,146,145,158,164,43,174,184,310,311,64,68,71,202,224,98,101,232,123 2434,678,98,1785,468,164,2977,64,1677,68,897,224,3401,3236,1128,2788,310,1248,2538,2790,3314,1286,12,3315,985,123,145,3367,3019,184,232,2714,2302,1637,3418,254,2632,1482,2062,3156,2229,174,158,3132,272,311,43,2725,2,1968,1911,1259,101,146,202,881,998,71,2371,1315,2849,15,2696,324,2034,1666,438,2339,1605,1119,3040 -0.4569583228314796,0.447397619113444,2.5388692262913795,-0.151577544698465,0.6834693746272135,1.8171233074337798,-0.7833273588538234,3.0426662360183325,-0.10627094673633292,2.993031551841918,0.28357365910325655,1.4328472746723286,-1.8631817950549134,-1.1062863390031978,0.15704238472925763,-0.6551091457204445,1.036063009474167,0.09253370913532158,-0.5057234167351391,-0.6551091457204445,-1.2766888241918128,0.07084055395748909,4.222429217331235,-1.2766888241918128,0.24175657929060165,2.2187310778900433,2.0142315842992913,-1.4839299067547875,-0.8093982448803362,1.6444566286616846,1.3995215238872651,-0.6047865559806115,-0.38473594847995757,-0.08377571033449493,-2.614938713691235,1.2468635762934643,-0.5549954789805401,-0.01690917370953021,-0.2667413189986047,-0.9689694457036316,-0.3371883420413084,1.7078960893112645,1.8479240879335823,-0.9419899846973533,1.1775484830852023,1.036063009474167,3.413286496271575,-0.6047865559806115,4.706308247813215,-0.22034471621492466,-0.19731314994998111,0.09253370913532158,2.5117605953310402,2.0142315842992913,1.5315716196659703,0.3043501904123781,0.24175657929060165,2.917749605386218,-0.40868858056019347,0.07084055395748909,-0.6804737926663148,4.131016779152228,-0.5798253703616462,1.000074973722675,-0.24348703633272678,-0.08377571033449493,0.7407953762815624,-0.38473594847995757,-0.061384384139230704,0.17835812614782434,-0.8093982448803362 3430 Cation transmembrane transporter activity 34 65 3.448689315153934 0.0005633144348766 Q13423,Q93050,Q9HD20,Q9Y619,P14854,Q9H9B4,P55011,P20020,O43772,O95202,P06576,Q15043,O75964,Q9UM00,Q8NE86,P13073,P24539,Q96ES6,P12235,P47985,P56385,Q00535,Q4KMQ2,P00403,Q96NB2,Q9Y487,P30825,Q9UDW1,Q9Y6M7,Q70HW3,O43808,P05141,P16615,Q7KZN9 Functions GO Molecular function msigdb_gomf 130,136,137,266,392,530,394,278,152,154,536,415,33,558,425,178,183,57,182,191,446,582,608,213,352,94,225,92,619,97,486,488,249,257 152,486,3268,33,154,213,897,488,536,3234,2785,3372,2164,1245,1739,182,178,392,249,278,2296,1475,3333,1049,183,2214,225,1051,2001,1094,2546,191,3255,394,2588,446,2360,2012,1690,582,130,415,1699,608,1107,97,257,425,802,136,57,352,2963,1006,1150,2850,530,137,92,2491,558,94,639,266,619 1.8937948621783494,0.6642150900524303,-1.1623836255706177,3.5731076371518076,1.8785482781004688,1.4659622290827485,0.28357365910325655,0.6642150900524303,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-1.5143297421023834,-0.31359071053648363,0.09253370913532158,-0.12887118746947637,1.6444566286616846,1.6603878760836814,0.816233531485841,1.2640484788395443,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,0.19958181332532843,1.6444566286616846,-0.3371883420413084,1.4328472746723286,0.19958181332532843,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,1.5963727964305452,-1.1342490728645735,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.24348703633272678,-0.10627094673633292,0.5471155860670778,2.1610865858455655,0.7786548166059916,-0.10627094673633292,0.5273305006198339,0.17835812614782434,2.552373754198136,1.2468635762934643,0.7597604826477616,0.3661616464083245,2.1174474931929272,3.1527758461637907,0.9089823832894932,-0.7574012545226345,0.24175657929060165,0.15704238472925763,-0.6804737926663148,0.6254843056815558,2.1028225946561765,2.6194057651180533,-0.4569583228314796,0.5864529093583782,2.6060641851362782,0.5074668730496471,1.2123219939175685,0.5273305006198339 3430 Inner mitochondrial membrane protein complex 30 76 3.4225804089374785 0.0006202974811622 Q96CU9,Q96IX5,P14406,P14854,Q9BUR5,Q9P0J0,O43676,O60830,P21912,O75964,Q9Y512,Q8NE86,P13073,P24539,Q99595,Q86Y39,Q9Y584,P47985,P56385,P03886,Q13505,O14949,P00403,P12236,Q9UDW1,Q5XKP0,O14925,P22695,Q99623,Q8IYU8 Localization GO Cellular component msigdb_gocc 263,396,9,392,275,149,25,30,282,33,419,425,178,183,56,188,62,191,446,74,75,82,213,218,92,357,122,106,383,250 1086,1941,122,82,25,2975,30,2387,1206,3093,758,681,2438,3268,33,839,3215,2620,978,213,74,536,1245,2666,1739,218,178,9,392,3127,3128,3048,2296,282,106,183,2214,3112,2866,1051,1955,2001,3373,191,3255,3362,492,2588,446,75,2837,905,666,991,797,357,585,188,250,425,263,396,56,383,275,2851,1321,3037,149,92,1609,2155,419,62,2618,482 0.17835812614782434,-0.22034471621492466,2.233047134387105,2.7380578010529537,3.8372261164826145,-0.7833273588538234,3.684618516209035,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.3865954317326442,0.447397619113444,-0.4569583228314796,-1.1623836255706177,3.5731076371518076,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.6060065128039738,0.09253370913532158,-0.5798253703616462,-0.12887118746947637,1.4494309133701686,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,-0.8356157493053581,-0.38473594847995757,1.1425395010761892,2.4019708945127647,1.6444566286616846,-0.3371883420413084,-0.9151668939436284,-0.7059762210511288,0.19958181332532843,-0.22034471621492466,-0.24348703633272678,-1.5449371974827035,1.5963727964305452,-1.1342490728645735,-1.4537345413628453,0.6642150900524303,-0.5302953342350691,0.7217588966997998,2.854234483045071,-0.6804737926663148,0.28357365910325655,0.4675011541744141,0.24175657929060165,0.3661616464083245,0.8905672747951905,0.5471155860670778,1.6124494198193353,1.2640484788395443,0.7597604826477616,1.2296215579874639,0.816233531485841,3.1648792186751504,0.8349190753908383,1.1775484830852023,-0.6804737926663148,0.07084055395748909,-0.8093982448803362,1.9392759124745347,2.6194057651180533,-0.061384384139230704,-0.2901087935675131,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.6834693746272135 3430 Lipid localization 19 80 3.4224896640878253 0.0006205045689109 P30536,Q9BQE5,Q14534,Q9BUR5,Q9H2V7,Q14108,Q99720,O43772,Q9Y6B6,Q14849,P23786,Q9BXW6,P04062,Q8WTV0,P07602,O15118,O14678,P17900,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 12,15,272,275,148,22,24,152,300,43,63,324,68,71,77,98,222,104,243 1241,3404,2739,222,678,98,319,152,486,2099,2160,1208,1788,1738,3008,68,1890,3234,2785,77,3011,1414,429,595,1518,104,1248,2538,63,1286,2824,12,1842,985,873,1574,1482,2062,1294,2460,2119,2266,22,272,43,608,825,881,3187,774,459,714,3329,71,2371,569,1315,24,15,2524,275,1717,324,746,1149,2034,148,1505,2086,1875,243,1876,1877,2339,1934,520,3191,2288,1777,300 0.09253370913532158,-2.0313624559825123,-0.6298806123677426,1.4328472746723286,0.447397619113444,2.5388692262913795,1.000074973722675,1.8937948621783494,0.6642150900524303,-0.2901087935675131,-0.31359071053648363,0.11413110287400714,-0.151577544698465,-0.12887118746947637,-0.8093982448803362,2.993031551841918,-0.19731314994998111,-1.1062863390031978,-0.6551091457204445,2.8157767839559593,-0.8093982448803362,0.005176812076117423,0.7407953762815624,0.5273305006198339,-0.03909589167063334,2.4571398271524862,0.09253370913532158,-0.5057234167351391,3.0673208707632353,0.07084055395748909,-0.6804737926663148,4.222429217331235,-0.17439114903384173,0.24175657929060165,0.3043501904123781,-0.061384384139230704,-0.01690917370953021,-0.2667413189986047,0.07084055395748909,-0.4569583228314796,-0.2901087935675131,-0.36090298236806184,3.9859536481432736,1.1775484830852023,3.413286496271575,0.5273305006198339,0.3456433744169804,0.3043501904123781,-1.023405807478901,0.3865954317326442,0.7026504351173741,0.4272126540305929,-1.3057195477388794,2.917749605386218,-0.40868858056019347,0.5668228264787173,0.07084055395748909,3.8907768973797325,4.131016779152228,-0.4812782346091039,1.1775484830852023,-0.10627094673633292,1.000074973722675,0.406945511095729,0.15704238472925763,-0.24348703633272678,1.9392759124745347,-0.01690917370953021,-0.2667413189986047,-0.17439114903384173,1.3322253587909487,-0.17439114903384173,-0.17439114903384173,-0.38473594847995757,-0.19731314994998111,0.6448869477951056,-1.023405807478901,-0.36090298236806184,-0.12887118746947637,1.0895765601315317 3430 Lipid binding 29 156 3.38442681793519 0.0007132703024061 Q13277,P30536,P45880,Q9BQE5,A6NIH7,Q9Y5X3,P38435,Q9H4A6,P21796,Q14108,Q9UM22,Q14849,O43292,P50897,Q99584,Q9BXW6,P04062,Q8WTV0,P07602,P53367,Q8NCC3,O00264,Q15067,O15118,O14773,Q07812,Q9NZJ7,O15173,Q13432 Functions GO Molecular function msigdb_gomf 260,12,13,15,14,270,145,268,20,22,34,43,177,53,317,324,68,71,77,209,84,216,350,98,110,368,243,117,125 1241,14,216,2817,1367,814,815,2739,110,930,1329,98,117,680,2776,177,1618,1467,2343,932,1621,3266,1368,1785,640,2977,2104,682,1125,68,1890,897,2785,77,1791,3372,444,3235,3398,2295,2441,786,2210,2583,1742,2909,1418,20,1248,2538,2709,942,2710,2824,2948,12,2263,3348,985,3050,145,13,1957,1096,873,53,3152,2829,3171,209,1058,2716,3183,1482,2061,2062,1532,1294,368,1381,1964,766,1299,260,125,2512,1139,2232,22,1578,43,3079,350,3158,1434,2990,2473,1144,1069,3100,3284,1497,1394,84,2130,71,1447,588,1313,2076,855,1816,3104,1232,2764,1315,1501,317,383,3319,3245,2608,15,2524,454,1717,324,746,2033,2034,834,268,923,1554,1719,243,1824,1462,2530,520,2615,34,3165,2200,1608,2700,1325,1828,2153,1611,2382,698,2384,573,270,895 0.09253370913532158,4.131016779152228,1.4494309133701686,-0.6804737926663148,0.027163091494653614,0.3456433744169804,0.3456433744169804,-0.6298806123677426,2.360226918485896,0.2627094020641012,0.04905067418434559,2.5388692262913795,2.2757707336590367,0.447397619113444,-0.6551091457204445,1.6603878760836814,-0.08377571033449493,-0.01690917370953021,-0.40868858056019347,0.2627094020641012,-0.08377571033449493,-1.1623836255706177,0.027163091494653614,-0.151577544698465,0.487523996503178,-0.7833273588538234,-0.2901087935675131,0.447397619113444,0.15704238472925763,2.993031551841918,-0.19731314994998111,0.28357365910325655,-0.6551091457204445,2.8157767839559593,-0.151577544698465,-1.5143297421023834,0.7217588966997998,-1.1062863390031978,-1.7976755345030844,-0.38473594847995757,-0.4569583228314796,0.3661616464083245,-0.3371883420413084,-0.5302953342350691,-0.12887118746947637,-0.7316181307528602,0.005176812076117423,3.9859536481432736,0.09253370913532158,-0.5057234167351391,-0.6047865559806115,0.2627094020641012,-0.6047865559806115,-0.6804737926663148,-0.7574012545226345,4.222429217331235,-0.36090298236806184,-1.3643448569490237,0.24175657929060165,-0.8356157493053581,2.0142315842992913,4.222429217331235,-0.22034471621492466,0.17835812614782434,0.3043501904123781,3.2250123758744826,-0.9689694457036316,-0.6804737926663148,-0.9961073484547495,1.4988693711510455,0.19958181332532843,-0.6047865559806115,-1.023405807478901,-0.01690917370953021,-0.2667413189986047,-0.2667413189986047,-0.03909589167063334,0.07084055395748909,0.8535361731217637,0.027163091494653614,-0.22034471621492466,0.3865954317326442,0.07084055395748909,1.2296215579874639,2.1899853400179143,-0.4812782346091039,0.15704238472925763,-0.3371883420413084,3.9859536481432736,-0.061384384139230704,3.413286496271575,-0.8619817453617755,0.9089823832894932,-0.9689694457036316,0.005176812076117423,-0.7833273588538234,-0.4569583228314796,0.15704238472925763,0.19958181332532843,-0.8884981438055674,-1.1906923971648218,-0.01690917370953021,0.027163091494653614,2.6987880108067723,-0.2901087935675131,2.917749605386218,0.005176812076117423,0.5471155860670778,0.07084055395748909,-0.2667413189986047,0.32503982365867656,-0.151577544698465,-0.8884981438055674,0.11413110287400714,-0.6298806123677426,0.07084055395748909,-0.01690917370953021,1.0181005541038732,0.8349190753908383,-1.2766888241918128,-1.1062863390031978,-0.5302953342350691,4.131016779152228,-0.4812782346091039,0.7217588966997998,-0.10627094673633292,1.000074973722675,0.406945511095729,-0.24348703633272678,-0.24348703633272678,0.3456433744169804,1.1949644490190432,0.28357365910325655,-0.03909589167063334,-0.10627094673633292,1.3322253587909487,-0.151577544698465,0.005176812076117423,-0.4812782346091039,0.6448869477951056,-0.5302953342350691,3.5618375403217266,-0.9689694457036316,-0.31359071053648363,-0.061384384139230704,-0.5798253703616462,0.07084055395748909,-0.151577544698465,-0.2901087935675131,-0.061384384139230704,-0.40868858056019347,0.447397619113444,-0.40868858056019347,0.5668228264787173,1.1949644490190432,0.3043501904123781 3430 Active transmembrane transporter activity 31 74 3.367737211283232 0.0007578779753985 P53985,Q9NUT2,Q9HD20,P55011,P14854,Q9P0J0,P20020,O43676,O95202,Q15043,Q8NE86,P13073,Q9UBX3,P08183,Q96ES6,P12235,P47985,Q03519,P03886,Q9Y6M9,P51798,P00403,Q03518,P12236,Q9UDW1,O14678,Q15388,P51970,P05141,P16615,Q7KZN9 Functions GO Molecular function msigdb_gomf 509,398,137,394,392,149,278,25,154,415,425,178,50,429,57,182,191,198,74,482,335,213,86,218,92,222,355,492,488,249,257 1086,1941,222,1019,25,2975,623,2387,1206,3093,681,2438,839,3215,154,2620,978,213,74,897,488,536,429,2164,1245,1739,182,218,178,392,249,3048,278,2296,1475,3333,1049,1286,3112,1051,1094,2546,191,3362,335,492,1290,509,394,2360,1690,739,86,198,415,355,1699,2837,905,257,425,57,1006,2850,137,2574,398,149,50,92,2491,639,619,482 0.17835812614782434,-0.22034471621492466,1.4328472746723286,0.22071433819033928,3.8372261164826145,-0.7833273588538234,0.5074668730496471,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,0.32503982365867656,-1.0784930750204527,1.8785482781004688,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.28357365910325655,0.6642150900524303,0.6060065128039738,0.7407953762815624,-0.31359071053648363,0.09253370913532158,-0.12887118746947637,1.6444566286616846,1.4494309133701686,1.6603878760836814,0.816233531485841,1.2640484788395443,-0.8356157493053581,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,0.19958181332532843,0.07084055395748909,-0.9151668939436284,0.19958181332532843,0.17835812614782434,-0.5057234167351391,1.5963727964305452,-1.4537345413628453,0.945614424806558,0.6642150900524303,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.40868858056019347,-0.10627094673633292,0.406945511095729,2.672453216244307,1.5640718300941014,0.7786548166059916,0.8905672747951905,-0.10627094673633292,-0.6804737926663148,0.28357365910325655,1.2468635762934643,0.7597604826477616,3.1527758461637907,0.24175657929060165,-0.6804737926663148,2.1028225946561765,-0.5057234167351391,0.816233531485841,1.9392759124745347,3.2845170686821423,2.6194057651180533,-0.4569583228314796,0.5074668730496471,0.5273305006198339,0.6834693746272135 3430 Predicted secreted proteins 20 53 3.3648165879174763 0.0007659455637061 P80303,P43490,Q15165,Q9Y4P3,Q9BUR5,Q9H9S5,Q14667,Q9UM22,Q02818,Q9Y287,Q9HB40,Q99584,Q8WUJ1,P09429,Q9UMX5,P14735,O94919,P05067,Q9BTY2,Q9NZ08 Functions Protein Atlas Protein class protein_atlas_protein_class 0,134,8,269,275,411,284,34,36,166,55,317,66,444,328,330,206,224,361,386 699,3278,1204,548,1786,868,206,732,1890,224,1022,2785,2865,444,3013,3269,1518,330,523,3347,2053,819,134,1750,1029,1482,1216,0,36,1253,474,1381,2462,284,8,1914,3329,2129,66,1863,2274,317,1867,361,275,2248,411,55,386,34,328,166,269 0.4272126540305929,-1.1906923971648218,0.11413110287400714,0.5864529093583782,-0.151577544698465,0.3043501904123781,1.5152459271739311,0.406945511095729,-0.19731314994998111,1.4328472746723286,0.22071433819033928,-0.6551091457204445,-0.7059762210511288,0.7217588966997998,-0.8093982448803362,-1.1623836255706177,-0.03909589167063334,0.9638324211451322,0.6254843056815558,-1.3643448569490237,-0.2667413189986047,0.3456433744169804,2.1465792509661505,-0.12887118746947637,0.22071433819033928,-0.01690917370953021,0.11413110287400714,5.333361777399175,3.527894748469767,0.09253370913532158,0.6834693746272135,0.027163091494653614,-0.4569583228314796,1.1425395010761892,4.469236267458811,-0.19731314994998111,-1.3057195477388794,-0.2901087935675131,3.0302984430490625,-0.17439114903384173,-0.36090298236806184,1.0181005541038732,-0.17439114903384173,0.8905672747951905,1.1775484830852023,-0.3371883420413084,0.7974789711276091,3.1769568474904344,0.8349190753908383,3.5618375403217266,0.9819857656994402,1.8016559746006866,1.1949644490190432 3430 Mitochondrial transmembrane transport 25 51 3.360658020095409 0.0007775703667345 Q9NUT2,Q9Y619,Q9H9B4,P21796,Q9BQT8,O43772,O95202,O60830,O75964,Q9BSK2,Q8NE86,Q99595,P24539,P12235,P23786,P56385,P12236,Q96NB2,Q15388,Q8IYU8,Q9UJZ1,P05141,Q6P4A7,Q9H2D1,O14925 Processes and pathways GO Biological process msigdb_gobp 398,266,530,20,409,152,154,30,33,165,425,56,183,182,63,446,218,352,355,250,520,488,247,120,122 122,728,152,30,623,2900,1369,3268,33,3150,154,937,730,2293,488,536,3398,182,218,20,63,183,2214,2001,3255,1574,1290,2588,446,1690,355,1912,991,247,250,425,2993,1352,352,56,409,165,120,2850,530,2851,398,967,520,2155,266 2.233047134387105,0.406945511095729,1.8937948621783494,3.684618516209035,0.5074668730496471,-0.7316181307528602,0.027163091494653614,-1.1623836255706177,3.5731076371518076,-0.9689694457036316,1.8785482781004688,0.2627094020641012,0.406945511095729,-0.38473594847995757,0.6642150900524303,0.6060065128039738,-1.7976755345030844,1.6444566286616846,1.4494309133701686,3.9859536481432736,3.0673208707632353,1.6444566286616846,-0.3371883420413084,-0.24348703633272678,-1.1342490728645735,-0.061384384139230704,0.07084055395748909,-0.5302953342350691,0.7217588966997998,-0.10627094673633292,0.8905672747951905,-0.19731314994998111,0.24175657929060165,1.2811766906485145,1.2640484788395443,0.7597604826477616,-0.7833273588538234,0.04905067418434559,0.9089823832894932,3.1648792186751504,0.7974789711276091,1.8171233074337798,2.2615667415404976,-0.6804737926663148,0.6254843056815558,-0.6804737926663148,0.816233531485841,0.2627094020641012,0.6448869477951056,-0.2901087935675131,1.2123219939175685 3430 Membrane protein complex 87 302 3.35997686481463 0.0007794899967903 Q13546,Q9NS69,P01889,P14406,P45880,Q6NTF9,P21796,O43676,Q8N4H5,O60830,P42574,Q8N511,O75955,O75964,O15400,P67812,P06576,Q9C0H2,Q99595,O95487,Q9Y584,Q92643,Q6UXV4,P63218,P03886,Q13505,O94901,O14949,Q03518,Q9UDW1,Q9Y487,Q9P2W9,P22695,O14925,Q9Y3B3,Q93050,Q9P0J0,O43292,P13073,Q9Y5M8,P24539,P12235,Q86Y39,P47985,Q03519,Q53GQ0,P00403,Q9UBU6,Q9BUN8,P12236,O14678,Q9NR31,Q8IYU8,O95249,Q13277,Q96CU9,Q9Y5X3,Q8TCT9,Q9BUR5,P21912,Q9Y277,Q9Y6B6,Q13190,P0DP25,P49755,P51798,Q15388,Q5XKP0,Q07812,Q99623,P51571,Q9NUT2,Q96IX5,P14854,Q9Y512,Q15041,Q8NE86,Q15904,P56385,P09429,O15269,Q9Y6M9,P49327,P51970,O00203,P05141,Q9NPA0 Localization GO Cellular component msigdb_gocc 512,3,507,9,13,541,20,25,29,30,537,32,534,33,532,35,536,45,56,561,62,588,585,581,74,75,574,82,86,92,94,107,106,122,133,136,149,177,178,180,183,182,188,191,198,202,213,215,214,218,222,248,250,258,260,263,270,274,275,282,294,300,301,304,315,335,355,357,368,383,376,398,396,392,419,424,425,434,446,444,441,482,471,492,483,488,519 483,1086,2859,814,1615,1941,815,1275,659,222,3148,122,82,2097,441,1673,532,727,1019,177,25,2975,1465,2343,2662,932,30,2387,1206,1674,3093,785,758,1737,681,2438,3268,534,33,3150,2103,869,574,2104,2781,839,3215,1125,258,2620,1208,561,1676,978,2293,213,507,732,74,684,1627,1281,2707,897,488,2665,536,3234,2785,2164,1245,2346,444,3217,3151,2666,304,1210,1739,3398,2210,182,218,178,9,392,1792,3127,3128,2536,2746,3253,3048,2296,1475,3333,20,282,3196,106,1840,183,2214,3395,3112,3334,3113,2866,1051,2910,2542,1955,1341,2001,1094,2546,3373,2398,2793,537,13,1374,598,191,3255,1250,471,2453,315,3362,376,335,1174,492,2114,1029,1480,2673,1058,2170,2796,2716,1345,2588,446,3356,3183,2797,2360,2012,2633,1641,3317,1379,2677,2401,581,35,1531,86,198,1533,1297,368,2266,2636,1964,1348,301,260,1179,879,2512,75,512,2232,2559,1142,1649,768,1578,688,3282,424,2236,1064,355,990,434,2837,905,666,991,608,202,797,1702,1304,357,881,626,541,585,188,714,1392,1393,250,1443,29,32,2242,1977,2129,425,2644,1112,274,1446,2071,717,801,588,2074,136,2188,1231,1188,263,1816,396,2029,3176,2483,3244,1038,1452,56,383,2693,1769,1502,1005,214,275,3427,45,1598,1150,1008,1320,834,2326,3121,2851,519,964,248,3,398,1321,2197,3037,1195,149,1989,107,1013,1360,1825,215,1118,3412,92,1509,1406,2491,2286,2737,3165,1608,1121,1511,1609,294,3166,784,133,94,2155,419,62,2618,639,180,270,811,1777,3330,300,895,482 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3430 Lipid metabolic process 91 294 3.357033460871764 0.0007878357756727 Q6IAN0,Q15392,P53985,Q9P035,P30536,Q9BQE5,Q8N4Q0,P07099,Q16134,P06576,P16278,Q9NPH0,P52429,Q14849,A8MXV4,P50897,Q8NF37,Q9HB40,P43034,Q96G23,Q8IXJ6,P23786,O95470,P04062,Q8WTV0,P07602,P51648,O75844,Q8NCC3,Q06136,O15118,Q15800,P17900,Q86UY6,O14773,Q8TBX8,Q8NHP8,P37268,Q8N2A8,Q8NBX0,Q16850,P38435,Q13510,O76062,Q9H7Z7,Q06520,O43292,P48449,Q86YN1,A1L0T0,Q53GQ0,O00116,P49356,P05067,O14678,O60512,P49748,Q9NUQ2,P27544,Q9NZJ7,P54646,Q14534,Q8NCG7,P16435,Q14739,Q9BXW6,Q13315,Q15067,P42345,Q16836,Q07812,Q9BT22,Q99623,Q6NUM9,P15289,P06280,O95864,Q2TAA5,O15228,Q9UBM7,P48651,O43681,Q96N66,P21964,O15269,Q9BTU6,O75845,P49327,O43808,O00767,Q9UJZ1 Processes and pathways GO Biological process msigdb_gobp 514,2,509,531,12,15,16,18,539,536,38,40,553,43,46,53,568,55,564,61,587,63,64,68,71,77,79,81,84,87,98,101,104,109,110,112,119,123,132,135,146,145,158,164,172,174,177,184,185,195,202,205,219,224,222,231,232,235,239,243,254,272,302,310,311,324,332,350,354,356,368,371,383,380,374,389,388,403,421,438,431,428,451,445,441,480,468,471,486,484,520 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3430 Steroid binding 9 23 3.348808652212912 0.0008115982593801 O15118,P04062,Q14849,P30536,P45880,P38435,P21796,O15173,Q14108 Functions GO Molecular function msigdb_gomf 98,68,43,12,13,145,20,117,22 216,98,117,1785,2977,68,897,3372,20,1248,2538,12,985,145,13,1482,22,43,1315,1717,324,746,2034 1.4494309133701686,2.5388692262913795,2.2757707336590367,-0.151577544698465,-0.7833273588538234,2.993031551841918,0.28357365910325655,-1.5143297421023834,3.9859536481432736,0.09253370913532158,-0.5057234167351391,4.222429217331235,0.24175657929060165,2.0142315842992913,4.222429217331235,-0.01690917370953021,3.9859536481432736,3.413286496271575,0.07084055395748909,-0.10627094673633292,1.000074973722675,0.406945511095729,-0.24348703633272678 3430 Tetrapyrrole binding 9 18 3.330809067303828 0.0008659397526886 Q8WUJ1,P30519,O43169,Q9H7Z7,Q16850,P09601,Q6UW02,O15173,O00264 Functions GO Molecular function msigdb_gomf 66,1,10,172,146,17,115,117,216 216,117,10,1245,17,1839,1,686,146,115,257,66,2078,857,172,2930,1994,1201 1.4494309133701686,2.2757707336590367,4.3124581612681805,0.09253370913532158,4.05893051652828,-0.17439114903384173,5.005721299000376,0.447397619113444,2.0142315842992913,2.3322196827838484,1.2468635762934643,3.0302984430490625,-0.2667413189986047,0.32503982365867656,1.7236380473068795,-0.7316181307528602,-0.22034471621492466,0.13563368348203628 3430 Mental deterioration 29 100 3.281951449171773 0.0010309135372852 P15289,P42858,P14854,Q9BQE5,Q14108,P21912,Q13510,Q96RL7,P16278,Q9Y287,P50897,O43681,O95470,P21964,P04062,P03886,P07602,P00403,Q9Y487,P05067,O15118,Q5XKP0,P17900,P27544,Q9NZJ7,O75503,Q03164,Q9NPL8,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,259,392,15,22,282,158,292,38,166,53,428,64,445,68,74,77,213,94,224,98,357,104,239,243,116,244,372,124 1367,98,428,533,1467,2344,506,1206,116,455,2440,64,2293,213,74,68,1678,704,224,1336,77,3011,1370,2786,3323,1740,392,374,38,1793,104,787,2668,282,445,2395,734,239,2866,871,1168,1094,2546,2450,259,2002,2300,2712,53,2951,2714,124,1423,2716,1482,1897,1531,244,951,2172,3056,1252,1298,767,2985,158,22,989,2834,2177,357,2919,1535,2411,1183,1858,1442,2184,1977,613,2320,2807,2418,2483,292,856,3318,2849,15,3177,3289,372,2968,243,1117,927,3040,166,94,1994 0.027163091494653614,2.5388692262913795,0.7407953762815624,0.6060065128039738,-0.01690917370953021,-0.40868858056019347,0.6448869477951056,0.11413110287400714,2.3181620708424706,0.7026504351173741,-0.4569583228314796,3.0426662360183325,-0.38473594847995757,1.4659622290827485,2.86699521405523,2.993031551841918,-0.10627094673633292,0.4272126540305929,1.4328472746723286,0.04905067418434559,2.8157767839559593,-0.8093982448803362,0.027163091494653614,-0.6551091457204445,-1.3057195477388794,-0.12887118746947637,0.816233531485841,0.8349190753908383,3.5165359909007803,-0.151577544698465,2.4571398271524862,0.3661616464083245,-0.5798253703616462,1.1425395010761892,0.7217588966997998,-0.4327622425712757,0.406945511095729,1.3491309609547064,-0.7059762210511288,0.3043501904123781,0.13563368348203628,0.17835812614782434,-0.5057234167351391,-0.4569583228314796,1.2296215579874639,-0.24348703633272678,-0.38473594847995757,-0.6047865559806115,3.2250123758744826,-0.7574012545226345,-0.6047865559806115,2.2187310778900433,0.005176812076117423,-0.6047865559806115,-0.01690917370953021,-0.19731314994998111,-0.03909589167063334,1.2982486318400348,0.2627094020641012,-0.31359071053648363,-0.8356157493053581,0.09253370913532158,0.07084055395748909,0.3865954317326442,-0.7833273588538234,1.8479240879335823,3.9859536481432736,0.24175657929060165,-0.6804737926663148,-0.31359071053648363,0.8905672747951905,-0.7316181307528602,-0.03909589167063334,-0.4327622425712757,0.13563368348203628,-0.17439114903384173,0.005176812076117423,-0.31359071053648363,-0.22034471621492466,0.5273305006198339,-0.38473594847995757,-0.6551091457204445,-0.4327622425712757,-0.4569583228314796,1.1249455781236504,0.32503982365867656,-1.2766888241918128,-0.6804737926663148,4.131016779152228,-0.9961073484547495,-1.1906923971648218,0.8535361731217637,-0.7574012545226345,1.3322253587909487,0.17835812614782434,0.28357365910325655,-0.8093982448803362,1.8016559746006866,2.6060641851362782,-0.22034471621492466 3430 Anion transmembrane transporter activity 24 43 3.275719054243827 0.0010539334608055 P53985,P55011,Q9Y619,Q9H9B4,P45880,P21796,Q9BQT8,Q15043,Q9Y277,Q8TB61,Q9C0H2,Q9UBX3,Q14728,O43681,P12235,Q4KMQ2,P51798,P12236,Q96NB2,Q9Y6M7,P30825,O43808,P05141,Q9H2D1 Functions GO Molecular function msigdb_gomf 509,394,266,530,13,20,409,415,294,39,45,50,565,428,182,608,335,218,352,619,225,486,488,120 2859,428,486,1369,937,488,2164,2049,595,182,218,20,225,13,335,1290,509,394,739,565,415,1699,608,3368,1182,3187,1393,39,352,1038,2963,409,1006,45,120,2850,530,50,967,294,266,3330,619 -0.7059762210511288,0.7407953762815624,0.6642150900524303,0.027163091494653614,0.2627094020641012,0.6642150900524303,-0.31359071053648363,-0.2667413189986047,0.5273305006198339,1.6444566286616846,1.4494309133701686,3.9859536481432736,1.4328472746723286,4.222429217331235,0.945614424806558,0.07084055395748909,0.6448869477951056,0.816233531485841,0.406945511095729,0.5668228264787173,0.7786548166059916,-0.10627094673633292,0.5273305006198339,-1.4839299067547875,0.13563368348203628,-1.023405807478901,0.027163091494653614,3.482324846985818,0.9089823832894932,0.22071433819033928,-0.7574012545226345,0.7974789711276091,0.24175657929060165,3.3784536775429674,2.2615667415404976,-0.6804737926663148,0.6254843056815558,3.2845170686821423,0.2627094020641012,1.107291420206707,1.2123219939175685,-1.3057195477388794,0.5273305006198339 3430 Protein localization to mitochondrion 20 59 3.269736187475432 0.001076478278261 P55786,Q9NS69,P30536,Q9P0J0,Q8N4H5,O60830,Q9Y512,Q9Y6C9,P0DP25,Q99595,Q9Y584,O14737,Q9Y5L4,Q8TB36,Q15388,P52789,Q07812,Q99797,O14925,Q15070 Processes and pathways GO Biological process msigdb_gobp 128,3,12,149,29,30,419,167,304,56,62,329,204,351,355,236,368,384,122,126 1995,483,1367,329,122,728,30,2900,3150,2820,3295,3193,730,2293,1161,304,3398,2442,2393,1630,2215,12,1570,2867,874,2009,1376,236,128,1426,368,1298,126,355,3134,991,797,609,667,29,351,1352,1925,56,384,833,2851,3,149,3123,2149,1609,1828,419,62,2618,420,204,167 -0.24348703633272678,0.6642150900524303,0.027163091494653614,0.9638324211451322,2.233047134387105,0.406945511095729,3.684618516209035,-0.7316181307528602,-0.9689694457036316,-0.6804737926663148,-1.2191778402877913,-1.0508669815631295,0.406945511095729,-0.38473594847995757,0.13563368348203628,1.0539628363107982,-1.7976755345030844,-0.4569583228314796,-0.4327622425712757,-0.08377571033449493,-0.3371883420413084,4.222429217331235,-0.061384384139230704,-0.7059762210511288,0.3043501904123781,-0.24348703633272678,0.027163091494653614,1.382778649014379,2.1755552047661753,0.005176812076117423,0.8535361731217637,0.07084055395748909,2.1899853400179143,0.8905672747951905,-0.9419899846973533,0.24175657929060165,0.3661616464083245,0.5273305006198339,0.4675011541744141,3.706665868419647,0.9089823832894932,0.04905067418434559,-0.19731314994998111,3.1648792186751504,0.8349190753908383,0.3456433744169804,-0.6804737926663148,4.706308247813215,1.9392759124745347,-0.9151668939436284,-0.2901087935675131,-0.061384384139230704,-0.151577544698465,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703,1.8016559746006866 3430 Intrinsic component of endoplasmic reticulum membrane 31 54 3.256605839884942 0.0011275288560539 P01889,Q9Y4P3,Q9P035,Q86XL3,Q8TCT9,Q6NTF9,Q9NZ01,O76062,Q15041,Q9UM00,Q8TB61,Q9HCU5,Q9UBM7,O43292,Q86YN1,O14975,P04439,Q96A33,O95470,Q92643,Q03519,O76024,O75844,Q9Y282,Q03518,Q9BUN8,Q15629,P57088,O00767,Q9NPA0,Q9NQC3 Localization GO Cellular component msigdb_gocc 507,269,531,140,274,541,676,164,424,558,39,695,438,177,185,678,684,323,64,588,198,455,81,85,86,214,89,493,484,519,127 1241,484,678,1019,177,81,455,164,64,507,684,1210,3395,705,3334,1376,493,2012,86,198,3185,3282,424,89,1702,541,2067,140,185,2242,39,274,588,2188,323,3244,1113,2524,214,1457,1598,834,695,519,127,676,531,1195,2897,438,558,85,269,1777 0.09253370913532158,0.6642150900524303,0.447397619113444,0.22071433819033928,1.6603878760836814,2.7510864124399865,0.7026504351173741,1.8171233074337798,3.0426662360183325,0.6448869477951056,0.447397619113444,0.11413110287400714,-1.7012045060061012,0.4272126540305929,-1.3349373118137702,0.027163091494653614,0.6642150900524303,-0.24348703633272678,2.672453216244307,1.5640718300941014,-1.023405807478901,-1.1906923971648218,0.7597604826477616,2.632715285689517,-0.10627094673633292,0.6060065128039738,-0.2667413189986047,2.073453552149814,1.6444566286616846,-0.3371883420413084,3.482324846985818,1.1775484830852023,0.5471155860670778,-0.31359071053648363,1.000074973722675,-1.1062863390031978,0.17835812614782434,-0.4812782346091039,1.4659622290827485,0.005176812076117423,-0.061384384139230704,0.3456433744169804,0.447397619113444,0.6448869477951056,2.1899853400179143,0.4675011541744141,0.6254843056815558,0.13563368348203628,-0.7059762210511288,0.7407953762815624,0.5864529093583782,2.685636217276718,1.1949644490190432,-0.12887118746947637 3430 Sterol metabolic process 18 42 3.249651528480841 0.0011554650167477 P54646,P05067,Q15392,O15118,O76062,P04062,Q15800,Q8WTV0,P49748,Q14849,Q9BQE5,Q14534,Q16850,Q06520,P48449,P16435,Q14739,P37268 Processes and pathways GO Biological process msigdb_gobp 254,224,2,98,164,68,101,71,232,43,15,272,146,174,184,310,311,123 98,1785,468,164,2977,1677,68,224,3236,1128,310,2790,3315,985,123,3367,3019,184,232,1637,3418,254,2632,1482,2062,3156,174,3132,272,311,43,2725,2,1259,101,146,71,15,324,438,2339,1119 2.5388692262913795,-0.151577544698465,0.6834693746272135,1.8171233074337798,-0.7833273588538234,-0.10627094673633292,2.993031551841918,1.4328472746723286,-1.1062863390031978,0.15704238472925763,1.036063009474167,-0.6551091457204445,-1.2766888241918128,0.24175657929060165,2.2187310778900433,-1.4839299067547875,-0.8093982448803362,1.6444566286616846,1.3995215238872651,-0.08377571033449493,-2.614938713691235,1.2468635762934643,-0.5549954789805401,-0.01690917370953021,-0.2667413189986047,-0.9689694457036316,1.7078960893112645,-0.9419899846973533,1.1775484830852023,1.036063009474167,3.413286496271575,-0.6047865559806115,4.706308247813215,0.09253370913532158,2.5117605953310402,2.0142315842992913,2.917749605386218,4.131016779152228,1.000074973722675,0.7407953762815624,-0.38473594847995757,0.17835812614782434 3430 Vesicles 63 328 3.2487712870156726 0.001159046287986 P35613,P30519,Q9HD45,P24390,Q13277,Q8IXH7,Q8NBX0,Q93050,Q9HD20,P55011,Q9Y5X3,Q9H4A6,Q14534,Q8N4Q0,Q9Y2G8,O95302,Q9H2V7,Q96SK2,O15127,O76062,Q9H8H2,P16278,Q9Y287,Q8TB61,Q86V85,Q9NUD5,Q14849,Q92564,P42785,Q96P70,P50897,Q86YN1,P16435,Q96ES6,Q9NPR9,O75153,P14859,Q9NRY5,P13473,A1L0T0,Q8WTV0,Q13315,P07602,P62424,P53367,Q8N5M9,Q8NCC3,Q96CN7,Q9BSH5,Q9Y487,P10253,P05067,O15118,P42345,P17900,Q3SXM5,P52789,Q15907,P10619,P35269,Q15363,Q96KP1,Q6P4A7 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 375,1,129,4,260,261,135,136,137,394,270,268,272,16,412,147,148,287,163,164,37,38,166,39,291,298,43,44,47,176,53,185,310,57,58,60,190,67,196,195,71,332,77,337,209,210,84,343,345,94,349,224,98,354,104,108,236,111,113,114,241,370,247 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3430 Secondary alcohol metabolic process 18 46 3.2211034708533286 0.0012769803569745 P54646,P05067,Q15392,O15118,O76062,P04062,Q15800,Q8WTV0,P49748,Q14849,Q9BQE5,Q14534,Q16850,Q06520,P48449,P16435,Q14739,P37268 Processes and pathways GO Biological process msigdb_gobp 254,224,2,98,164,68,101,71,232,43,15,272,146,174,184,310,311,123 98,2778,1785,468,1332,164,2977,1677,68,224,3236,1128,310,2790,3315,985,123,3019,184,1421,232,3256,1344,1637,3418,254,2632,1482,2062,3156,174,3132,272,311,43,2725,2,1259,101,146,71,3227,15,324,438,2339 2.5388692262913795,-0.6551091457204445,-0.151577544698465,0.6834693746272135,0.04905067418434559,1.8171233074337798,-0.7833273588538234,-0.10627094673633292,2.993031551841918,1.4328472746723286,-1.1062863390031978,0.15704238472925763,1.036063009474167,-0.6551091457204445,-1.2766888241918128,0.24175657929060165,2.2187310778900433,-0.8093982448803362,1.6444566286616846,0.005176812076117423,1.3995215238872651,-1.1342490728645735,0.04905067418434559,-0.08377571033449493,-2.614938713691235,1.2468635762934643,-0.5549954789805401,-0.01690917370953021,-0.2667413189986047,-0.9689694457036316,1.7078960893112645,-0.9419899846973533,1.1775484830852023,1.036063009474167,3.413286496271575,-0.6047865559806115,4.706308247813215,0.09253370913532158,2.5117605953310402,2.0142315842992913,2.917749605386218,-1.0784930750204527,4.131016779152228,1.000074973722675,0.7407953762815624,-0.38473594847995757 3430 Organic anion transport 20 43 3.2034372604016217 0.0013579762501023 P53985,O60831,P55011,Q9Y619,Q9H9B4,Q9BQT8,Q15041,Q8TB61,Q9UBX3,Q14728,P12235,P07602,P12236,Q96NB2,Q9Y6M7,P30825,O43808,Q9NZJ7,P05141,Q9H2D1 Processes and pathways GO Biological process msigdb_gobp 509,505,394,266,530,409,424,39,50,565,182,77,218,352,619,225,486,243,488,120 486,505,1369,817,937,1890,488,2665,77,2164,595,182,218,1518,1418,1286,225,1290,509,394,1902,739,565,424,710,1699,1182,3187,1393,39,352,2963,409,120,2850,530,2086,243,50,1119,967,266,619 0.6642150900524303,0.6448869477951056,0.027163091494653614,0.3456433744169804,0.2627094020641012,-0.19731314994998111,0.6642150900524303,-0.5798253703616462,2.8157767839559593,-0.31359071053648363,0.5273305006198339,1.6444566286616846,1.4494309133701686,-0.03909589167063334,0.005176812076117423,0.07084055395748909,1.4328472746723286,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.19731314994998111,0.406945511095729,0.5668228264787173,0.7597604826477616,0.4272126540305929,-0.10627094673633292,0.13563368348203628,-1.023405807478901,0.027163091494653614,3.482324846985818,0.9089823832894932,-0.7574012545226345,0.7974789711276091,2.2615667415404976,-0.6804737926663148,0.6254843056815558,-0.2667413189986047,1.3322253587909487,3.2845170686821423,0.17835812614782434,0.2627094020641012,1.2123219939175685,0.5273305006198339 3430 Receptor 12 33 3.198191181290281 0.0013829256470496 P57105,Q8WTV0,Q9NR77,O75381,A6NIH7,Q13641,Q6NTF9,Q14108,Q567V2,Q9BUN8,Q13432,Q9UQB8 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 162,71,297,549,14,526,541,22,150,214,125,93 14,1464,1019,1465,549,2104,1676,2665,2210,1567,2671,162,125,526,22,150,541,1439,586,71,2318,1072,3064,214,1598,859,1600,297,1459,1405,1556,1879,93 4.131016779152228,-0.01690917370953021,0.22071433819033928,-0.01690917370953021,0.5864529093583782,-0.2901087935675131,-0.10627094673633292,-0.5798253703616462,-0.3371883420413084,-0.061384384139230704,-0.5798253703616462,1.8325459149864132,2.1899853400179143,0.6254843056815558,3.9859536481432736,1.9241584043171278,0.6060065128039738,0.005176812076117423,0.5471155860670778,2.917749605386218,-0.38473594847995757,0.19958181332532843,-0.8356157493053581,1.4659622290827485,-0.061384384139230704,0.32503982365867656,-0.061384384139230704,1.0895765601315317,0.005176812076117423,0.027163091494653614,-0.03909589167063334,-0.17439114903384173,2.6060641851362782 3430 Serine hydrolase activity 6 18 3.1977044902846967 0.0013852615604545 P67812,Q16740,O14773,P42785,Q9H3G5,Q9HB40 Functions GO Molecular function msigdb_gomf 35,7,110,47,49,55 110,936,113,3074,1954,1522,47,2452,2587,35,7,1435,1652,609,541,909,49,55 2.360226918485896,0.2627094020641012,2.3322196827838484,-0.8619817453617755,-0.22034471621492466,-0.03909589167063334,3.3551136813137883,-0.4569583228314796,-0.5302953342350691,3.527894748469767,4.517401396572567,0.005176812076117423,-0.08377571033449493,0.5273305006198339,0.6060065128039738,0.28357365910325655,3.3551136813137883,3.1769568474904344 3430 Delusions 9 21 3.1970366928807508 0.001388472630756 P15289,P42858,Q96RL7,P04062,P07602,Q9BQE5,Q9NZJ7,P49770,O43681 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,259,292,68,77,15,243,432,428 1560,428,68,77,1370,374,445,2545,259,2002,432,1172,1534,1854,1591,292,15,1404,243,1407,967 -0.061384384139230704,0.7407953762815624,2.993031551841918,2.8157767839559593,0.027163091494653614,0.8349190753908383,0.7217588966997998,-0.5057234167351391,1.2296215579874639,-0.24348703633272678,0.7407953762815624,0.13563368348203628,-0.03909589167063334,-0.17439114903384173,-0.061384384139230704,1.1249455781236504,4.131016779152228,0.027163091494653614,1.3322253587909487,0.027163091494653614,0.2627094020641012 3430 serine protease 6 18 3.196689269995829 0.0013901459093959 P67812,Q16740,O14773,P42785,Q9H3G5,Q9HB40 Functions Panther Protein class panther_protein_class 35,7,110,47,49,55 110,113,2624,3074,1954,1522,47,2452,35,7,1435,1652,909,1443,3119,49,55,2490 2.360226918485896,2.3322196827838484,-0.5549954789805401,-0.8619817453617755,-0.22034471621492466,-0.03909589167063334,3.3551136813137883,-0.4569583228314796,3.527894748469767,4.517401396572567,0.005176812076117423,-0.08377571033449493,0.28357365910325655,0.005176812076117423,-0.9151668939436284,3.3551136813137883,3.1769568474904344,-0.4569583228314796 3430 er 35 88 3.163685884729212 0.0015578483310199 Q07065,Q15392,Q5HYI8,Q16850,Q8NHH9,Q9UM00,Q15041,Q9Y6B6,Q13190,Q96GC9,Q9Y5M8,P48449,P48651,Q14739,O96005,P49755,Q96N66,Q96A33,O95470,O15269,Q969V3,Q969Q5,Q06136,O00264,P18085,Q9Y487,O75845,Q9P2W9,Q8TBX8,Q15363,O00767,O15173,Q9NR31,Q9NPA0,Q9NQC3 Localization OpenCell Localization opencell_localization 256,2,265,146,416,558,424,300,301,569,180,184,431,311,181,315,451,323,64,441,461,207,87,216,469,94,468,107,112,241,484,117,248,519,127 216,484,117,441,1673,1674,785,468,817,1889,64,181,1738,1677,1627,1281,2209,469,1568,705,2398,598,184,431,315,3153,1376,2716,3356,2718,706,789,2633,3317,1575,1380,1576,87,256,1429,301,311,3282,424,241,2,1259,1756,146,265,1702,3274,3187,2124,1541,2242,3387,568,416,112,1112,1446,2132,207,461,323,569,451,2767,2524,3403,746,1457,3358,1871,519,127,248,890,1195,1876,107,558,1273,1122,94,180,300 1.4494309133701686,0.6642150900524303,2.2757707336590367,0.7217588966997998,-0.10627094673633292,-0.10627094673633292,0.3661616464083245,0.6834693746272135,0.3456433744169804,-0.19731314994998111,3.0426662360183325,1.6444566286616846,-0.12887118746947637,-0.10627094673633292,-0.08377571033449493,0.07084055395748909,-0.3371883420413084,0.6834693746272135,-0.061384384139230704,0.4272126540305929,-0.4327622425712757,0.5273305006198339,1.6444566286616846,0.7407953762815624,1.0181005541038732,-0.9689694457036316,0.027163091494653614,-0.6047865559806115,-1.4237405696271823,-0.6047865559806115,0.4272126540305929,0.3661616464083245,-0.5549954789805401,-1.2766888241918128,-0.061384384139230704,0.027163091494653614,-0.061384384139230704,2.672453216244307,1.2468635762934643,0.005176812076117423,1.071800525038966,1.036063009474167,-1.1906923971648218,0.7597604826477616,1.3491309609547064,4.706308247813215,0.09253370913532158,-0.12887118746947637,2.0142315842992913,1.2123219939175685,-0.10627094673633292,-1.1623836255706177,-1.023405807478901,-0.2901087935675131,-0.03909589167063334,-0.3371883420413084,-1.638037942852283,0.5668228264787173,0.7786548166059916,2.34624122931555,0.17835812614782434,0.005176812076117423,-0.2901087935675131,1.5152459271739311,0.7026504351173741,1.000074973722675,0.5668228264787173,0.7217588966997998,-0.6298806123677426,-0.4812782346091039,-1.9633114577538548,0.406945511095729,0.005176812076117423,-1.4237405696271823,-0.17439114903384173,0.6448869477951056,2.1899853400179143,1.2811766906485145,0.3043501904123781,0.13563368348203628,-0.17439114903384173,2.4019708945127647,0.5864529093583782,0.09253370913532158,0.17835812614782434,2.6060641851362782,1.6603878760836814,1.0895765601315317 3430 Receptor 16 42 3.1620358920273945 0.0015667025256198 P35613,Q14739,Q9NS69,P24390,O15118,Q8WTV0,P14735,O15031,Q9Y5M8,O15173,Q14108,Q99623,Q99720,O43731,P30825,O00264 Functions Protein Atlas Molecular function protein_atlas_molecular_function 375,311,3,4,98,71,330,169,180,117,22,383,24,59,225,216 216,3278,169,98,117,59,732,2665,577,3234,2209,2623,2050,1338,413,2210,3269,330,1567,1840,4,225,375,511,1216,1691,2266,22,311,1699,71,2844,802,633,383,24,3423,3,1405,1325,2289,180 1.4494309133701686,-1.1906923971648218,1.7705859554975645,2.5388692262913795,2.2757707336590367,3.104102422844003,0.406945511095729,-0.5798253703616462,0.5471155860670778,-1.1062863390031978,-0.3371883420413084,-0.5549954789805401,-0.2667413189986047,0.04905067418434559,0.7786548166059916,-0.3371883420413084,-1.1623836255706177,0.9638324211451322,-0.061384384139230704,-0.17439114903384173,4.687680585731818,1.4328472746723286,0.8349190753908383,0.6448869477951056,0.11413110287400714,-0.10627094673633292,-0.36090298236806184,3.9859536481432736,1.036063009474167,-0.10627094673633292,2.917749605386218,-0.6804737926663148,0.3661616464083245,0.5074668730496471,0.8349190753908383,3.8907768973797325,-2.891910638881035,4.706308247813215,0.027163091494653614,0.07084055395748909,-0.36090298236806184,1.6603878760836814 3430 Protein localization 26 77 3.155630087042733 0.0016015183134483 Q9NS69,P09601,P21796,Q8N4H5,O60830,Q9Y512,Q9Y5J9,Q9NR77,O15228,Q13190,A8MXV4,Q99595,P12235,Q9Y584,P14735,Q13505,Q9Y5L4,O00116,P51648,P12236,Q8TB36,P05067,Q15067,Q15388,P46379,O14925 Processes and pathways Reactome Pathways msigdb_reactome 3,17,20,29,30,419,420,297,421,301,46,56,182,62,330,75,204,205,79,218,351,224,350,355,121,122 46,205,2434,122,678,421,680,728,428,1514,486,30,549,3267,758,2900,3095,1369,1332,3150,2293,224,536,1245,3401,17,3398,182,218,330,20,2538,2214,1286,3315,3129,3373,842,121,600,1479,1344,79,2302,3356,2063,1298,2801,301,75,350,355,1435,991,609,478,29,1712,351,1073,56,3227,2851,297,3,3037,1876,2285,967,3191,1609,2151,419,62,2618,420,204 3.3667955634163027,1.5152459271739311,-0.4569583228314796,2.233047134387105,0.447397619113444,0.7597604826477616,0.447397619113444,0.406945511095729,0.7407953762815624,-0.03909589167063334,0.6642150900524303,3.684618516209035,0.5864529093583782,-1.1623836255706177,0.3865954317326442,-0.7316181307528602,-0.8884981438055674,0.027163091494653614,0.04905067418434559,-0.9689694457036316,-0.38473594847995757,1.4328472746723286,0.6060065128039738,0.09253370913532158,-1.8631817950549134,4.05893051652828,-1.7976755345030844,1.6444566286616846,1.4494309133701686,0.9638324211451322,3.9859536481432736,-0.5057234167351391,-0.3371883420413084,0.07084055395748909,-1.2766888241918128,-0.9419899846973533,-1.5449371974827035,0.32503982365867656,2.247325615021821,0.5273305006198339,-0.01690917370953021,0.04905067418434559,2.777052623692763,-0.38473594847995757,-1.4237405696271823,-0.2667413189986047,0.07084055395748909,-0.6551091457204445,1.071800525038966,2.854234483045071,0.9089823832894932,0.8905672747951905,0.005176812076117423,0.24175657929060165,0.5273305006198339,0.6834693746272135,3.706665868419647,-0.10627094673633292,0.9089823832894932,0.19958181332532843,3.1648792186751504,-1.0784930750204527,-0.6804737926663148,1.0895765601315317,4.706308247813215,-0.8093982448803362,-0.17439114903384173,-0.36090298236806184,0.2627094020641012,-1.023405807478901,-0.061384384139230704,-0.2901087935675131,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Mitochondrial carrier domain superfamily [IPR023395] 12 20 3.134812262604202 0.0017196412523967 Q70HW3,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3,O43808,Q9NZJ7,Q9BQT8,O43772,P12236,P12235,Q9H2D1 Sequence InterPro Superfamily interpro_homologous_superfamily 97,165,167,266,50,486,243,409,152,218,182,120 152,486,1369,488,182,218,1290,1690,739,1182,97,409,165,120,2850,243,50,967,266,167 1.8937948621783494,0.6642150900524303,0.027163091494653614,0.6642150900524303,1.6444566286616846,1.4494309133701686,0.07084055395748909,-0.10627094673633292,0.406945511095729,0.13563368348203628,2.552373754198136,0.7974789711276091,1.8171233074337798,2.2615667415404976,-0.6804737926663148,1.3322253587909487,3.2845170686821423,0.2627094020641012,1.2123219939175685,1.8016559746006866 3430 Mitochondrial substrate/solute carrier [IPR018108] 12 20 3.134812262604202 0.0017196412523967 Q70HW3,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3,O43808,Q9NZJ7,Q9BQT8,O43772,P12236,P12235,Q9H2D1 Sequence InterPro Repeat interpro_repeat 97,165,167,266,50,486,243,409,152,218,182,120 152,486,1369,488,182,218,1290,1690,739,1182,97,409,165,120,2850,243,50,967,266,167 1.8937948621783494,0.6642150900524303,0.027163091494653614,0.6642150900524303,1.6444566286616846,1.4494309133701686,0.07084055395748909,-0.10627094673633292,0.406945511095729,0.13563368348203628,2.552373754198136,0.7974789711276091,1.8171233074337798,2.2615667415404976,-0.6804737926663148,1.3322253587909487,3.2845170686821423,0.2627094020641012,1.2123219939175685,1.8016559746006866 3430 SLC25 family of mitochondrial transporters 12 20 3.134812262604202 0.0017196412523967 Q70HW3,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3,O43808,Q9NZJ7,Q9BQT8,O43772,P12236,P12235,Q9H2D1 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 97,165,167,266,50,486,243,409,152,218,182,120 152,486,1369,488,182,218,1290,1690,739,1182,97,409,165,120,2850,243,50,967,266,167 1.8937948621783494,0.6642150900524303,0.027163091494653614,0.6642150900524303,1.6444566286616846,1.4494309133701686,0.07084055395748909,-0.10627094673633292,0.406945511095729,0.13563368348203628,2.552373754198136,0.7974789711276091,1.8171233074337798,2.2615667415404976,-0.6804737926663148,1.3322253587909487,3.2845170686821423,0.2627094020641012,1.2123219939175685,1.8016559746006866 3430 Molecular transducer activity 8 34 3.1256230310984163 0.0017742883406675 O15118,Q8WTV0,O15031,P30536,O15173,Q14108,Q99720,Q15629 Functions GO Molecular function msigdb_gomf 98,71,169,12,117,22,24,89 3278,169,98,117,2665,3234,1338,2210,1567,12,2111,2671,471,1903,1691,2266,22,89,1699,2408,1439,71,2844,802,1113,633,24,214,2335,1405,2897,1509,2492,1778 -1.1906923971648218,1.7705859554975645,2.5388692262913795,2.2757707336590367,-0.5798253703616462,-1.1062863390031978,0.04905067418434559,-0.3371883420413084,-0.061384384139230704,4.222429217331235,-0.2901087935675131,-0.5798253703616462,0.6834693746272135,-0.19731314994998111,-0.10627094673633292,-0.36090298236806184,3.9859536481432736,2.632715285689517,-0.10627094673633292,-0.4327622425712757,0.005176812076117423,2.917749605386218,-0.6804737926663148,0.3661616464083245,0.17835812614782434,0.5074668730496471,3.8907768973797325,1.4659622290827485,-0.38473594847995757,0.027163091494653614,-0.7059762210511288,-0.01690917370953021,-0.4569583228314796,-0.12887118746947637 3430 Protein transport 59 274 3.0917111993725817 0.0019900635929548 P55060,O95249,Q9NS69,P24390,Q9Y3B3,O75165,O60831,Q9HD20,Q9Y5X3,Q2M389,A6NIH7,Q9H4A6,P52292,Q8N4H5,O60830,Q9C0E2,O15127,Q96RL7,Q9Y5J9,Q9BVK6,Q9Y6B6,O75381,Q9Y5X2,Q96P70,Q96QU8,Q99595,P20337,O43731,P49755,Q99584,Q9Y584,P61020,A0AVF1,P41208,Q03519,Q13505,Q9Y5L4,Q92973,Q7Z3C6,Q969Q5,Q8N5M9,O15397,Q03518,Q9BUN8,Q15629,P18085,P61970,Q15388,Q96D46,Q9BTX1,Q9P2W9,Q12907,O00203,Q15907,Q15363,Q96KP1,Q9NR31,O14925,Q13432 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 510,258,3,4,133,506,505,137,270,527,14,268,156,29,30,417,163,292,420,427,300,549,573,176,435,56,562,59,315,317,62,447,318,65,198,75,204,460,459,207,210,340,86,214,89,469,472,355,359,105,107,495,483,111,241,370,248,122,125 318,812,14,1730,2043,483,2257,1615,1731,1943,1831,1275,659,1123,867,122,930,1464,2158,1330,163,340,727,3070,728,1996,59,1465,2206,2819,2343,622,2940,932,1784,1621,1205,30,505,506,2160,549,785,758,1737,3180,2901,594,2103,2104,2781,1125,2903,258,1413,759,1208,561,2944,1676,2293,2049,1837,469,1417,562,1024,4,1571,1341,2056,2397,3050,65,2793,2505,1250,874,599,315,2547,1958,1479,1684,1685,3153,1376,1174,156,3131,2587,2114,1029,1480,2673,2796,510,2060,2507,3356,1799,2871,706,447,789,1346,2012,1641,472,2721,664,1378,2677,1529,1752,1575,86,198,1430,2554,2013,1643,1644,495,2756,125,75,2232,3133,2018,1434,241,355,990,89,111,527,991,1104,1703,1913,1436,2023,653,3029,1144,2479,459,992,714,3284,2414,2365,1497,1585,1394,29,210,853,2241,1977,1445,999,2690,828,829,2645,2318,1446,2132,2605,1447,801,1662,1313,460,207,803,1231,3206,1816,359,370,1232,1036,176,2483,435,292,1501,1113,2137,317,56,2693,1769,1005,105,214,427,3365,1928,2770,2139,417,1268,1008,1320,2928,268,1505,2611,2281,694,2326,3121,859,695,137,924,1820,1871,2283,248,2812,2089,3,1873,1875,2148,2197,3005,1989,2897,107,1360,1825,2575,1509,838,2427,1934,3039,1462,2530,2286,3067,2039,2253,1014,3165,2288,1608,969,725,1408,784,1082,133,1725,1122,2341,1883,62,2618,420,1728,204,698,2384,573,270,811,300 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3430 Active ion transmembrane transporter activity 19 38 3.0734904523381386 0.0021157045764941 Q9HD20,P55011,P14854,P20020,O95202,P06576,Q15043,P13073,Q96ES6,P12235,P47985,P51798,P00403,P12236,Q9Y6M7,Q9UDW1,P05141,P16615,Q7KZN9 Functions GO Molecular function msigdb_gomf 137,394,392,278,154,536,415,178,57,182,191,335,213,218,619,92,488,249,257 154,213,897,488,536,2164,1245,1739,182,218,178,392,249,278,2296,1475,3333,1049,1051,1094,2546,191,335,1290,394,2360,1690,739,415,257,57,1006,2850,137,92,2491,639,619 1.8785482781004688,1.4659622290827485,0.28357365910325655,0.6642150900524303,0.6060065128039738,-0.31359071053648363,0.09253370913532158,-0.12887118746947637,1.6444566286616846,1.4494309133701686,1.6603878760836814,0.816233531485841,1.2640484788395443,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,0.19958181332532843,0.19958181332532843,0.17835812614782434,-0.5057234167351391,1.5963727964305452,0.945614424806558,0.07084055395748909,0.816233531485841,-0.40868858056019347,-0.10627094673633292,0.406945511095729,0.7786548166059916,1.2468635762934643,3.1527758461637907,0.24175657929060165,-0.6804737926663148,2.1028225946561765,2.6194057651180533,-0.4569583228314796,0.5074668730496471,0.5273305006198339 3430 Dementia 15 58 3.0710576303109103 0.0021330197643403 Q13510,P05067,O15118,P42858,P04062,Q9Y287,P17900,P03886,P07602,P27544,Q9NZJ7,P00403,Q14108,Q9Y487,P21912 Drugs and Diseases Human Phenotype Ontology msigdb_hp 158,224,98,259,68,166,104,74,77,239,243,213,22,94,282 1367,98,428,1467,506,455,2293,213,74,68,1678,704,224,1336,77,2786,3323,374,104,2668,282,2395,734,239,2866,871,1168,1094,2546,259,2300,2714,1423,2716,1482,951,2172,1252,2985,158,22,989,2177,2411,1183,1442,2184,613,2807,2483,292,856,3318,243,1117,166,94,1994 0.027163091494653614,2.5388692262913795,0.7407953762815624,-0.01690917370953021,0.6448869477951056,0.7026504351173741,-0.38473594847995757,1.4659622290827485,2.86699521405523,2.993031551841918,-0.10627094673633292,0.4272126540305929,1.4328472746723286,0.04905067418434559,2.8157767839559593,-0.6551091457204445,-1.3057195477388794,0.8349190753908383,2.4571398271524862,-0.5798253703616462,1.1425395010761892,-0.4327622425712757,0.406945511095729,1.3491309609547064,-0.7059762210511288,0.3043501904123781,0.13563368348203628,0.17835812614782434,-0.5057234167351391,1.2296215579874639,-0.38473594847995757,-0.6047865559806115,0.005176812076117423,-0.6047865559806115,-0.01690917370953021,0.2627094020641012,-0.31359071053648363,0.09253370913532158,-0.7833273588538234,1.8479240879335823,3.9859536481432736,0.24175657929060165,-0.31359071053648363,-0.4327622425712757,0.13563368348203628,0.005176812076117423,-0.31359071053648363,0.5273305006198339,-0.6551091457204445,-0.4569583228314796,1.1249455781236504,0.32503982365867656,-1.2766888241918128,1.3322253587909487,0.17835812614782434,1.8016559746006866,2.6060641851362782,-0.22034471621492466 3430 Organic acid transmembrane transport 13 29 3.057794605603235 0.0022297234750208 O14678,P53985,Q15041,O60831,Q9Y619,Q9H2D1,Q9UBX3,Q9BQT8,P08183,O43772,Q96NB2,P30825,P23786 Processes and pathways GO Biological process msigdb_gobp 222,509,424,505,266,120,50,409,429,152,352,225,63 222,152,505,1369,817,937,2665,429,2164,595,63,1286,225,1842,1574,1290,509,739,424,1699,1393,352,409,120,2850,530,50,967,266 1.4328472746723286,1.8937948621783494,0.6448869477951056,0.027163091494653614,0.3456433744169804,0.2627094020641012,-0.5798253703616462,0.7407953762815624,-0.31359071053648363,0.5273305006198339,3.0673208707632353,0.07084055395748909,1.4328472746723286,-0.17439114903384173,-0.061384384139230704,0.07084055395748909,0.6448869477951056,0.406945511095729,0.7597604826477616,-0.10627094673633292,0.027163091494653614,0.9089823832894932,0.7974789711276091,2.2615667415404976,-0.6804737926663148,0.6254843056815558,3.2845170686821423,0.2627094020641012,1.2123219939175685 3430 Protein insertion into membrane 14 29 3.040752561319751 0.0023598767937946 Q96A33,P46379,Q9Y512,Q9NS69,Q9Y5J9,O14737,Q9Y5L4,Q07812,Q9P0J0,Q7L5D6,O43681,Q15629,Q15070,Q9Y584 Processes and pathways GO Biological process msigdb_gobp 323,121,419,3,420,329,204,368,149,478,428,89,126,62 329,428,1514,3150,1161,2215,2867,121,2012,368,3282,126,89,797,1702,478,2242,1352,323,519,3,1195,149,1609,419,62,2618,420,204 0.9638324211451322,0.7407953762815624,-0.03909589167063334,-0.9689694457036316,0.13563368348203628,-0.3371883420413084,-0.7059762210511288,2.247325615021821,-0.24348703633272678,0.8535361731217637,-1.1906923971648218,2.1899853400179143,2.632715285689517,0.3661616464083245,-0.10627094673633292,0.6834693746272135,-0.3371883420413084,0.04905067418434559,1.000074973722675,0.6448869477951056,4.706308247813215,0.13563368348203628,1.9392759124745347,-0.061384384139230704,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Vascular skin abnormality 32 125 3.0235205911492504 0.0024985202510863 P06280,P38435,P51812,Q13426,Q14108,P21912,P16278,Q9UBM7,P48651,Q14739,O15360,Q9NWM8,P21964,Q16625,P04062,P03886,Q13315,P51648,O75844,P51798,Q13126,P00403,Q06136,Q15427,Q9Y487,P22830,Q13535,Q96L58,Q8IZA0,P10619,P28340,Q07864 Drugs and Diseases Human Phenotype Ontology msigdb_hp 389,145,19,21,22,282,38,438,431,311,308,325,445,322,68,74,332,79,81,335,83,213,87,91,94,470,230,234,237,113,240,377 1995,2937,1087,308,2976,1204,1998,2100,1622,1206,2742,81,896,2162,1564,3331,213,507,2978,74,68,2582,389,2822,1162,113,1740,2500,3097,1892,38,1247,2536,2746,787,1474,3219,1418,282,445,3196,470,3395,240,1476,2217,1572,2542,1477,1094,2449,145,2546,2111,2218,431,874,471,2713,79,335,19,686,2673,1525,1423,2454,1295,2551,2460,2119,87,377,2266,953,1137,83,332,21,230,22,1855,311,3079,1698,91,1259,322,1808,610,713,2023,825,2839,1182,3187,2760,1068,237,3387,2131,2074,2188,3303,2028,234,1036,3226,2522,3319,806,887,1149,721,325,3228,438,1990,557,1240,1991,2340,1362,94,1728 -0.24348703633272678,-0.7574012545226345,0.17835812614782434,1.036063009474167,-0.7833273588538234,0.11413110287400714,-0.24348703633272678,-0.2901087935675131,-0.08377571033449493,0.11413110287400714,-0.6298806123677426,2.7510864124399865,0.28357365910325655,-0.31359071053648363,-0.061384384139230704,-1.3349373118137702,1.4659622290827485,0.6448869477951056,-0.7833273588538234,2.86699521405523,2.993031551841918,-0.5302953342350691,0.816233531485841,-0.6804737926663148,0.13563368348203628,2.3322196827838484,-0.12887118746947637,-0.4812782346091039,-0.8884981438055674,-0.19731314994998111,3.5165359909007803,0.09253370913532158,-0.5057234167351391,-0.6298806123677426,0.3661616464083245,-0.01690917370953021,-1.0784930750204527,0.005176812076117423,1.1425395010761892,0.7217588966997998,-1.0508669815631295,0.6834693746272135,-1.7012045060061012,1.3491309609547064,-0.01690917370953021,-0.3371883420413084,-0.061384384139230704,-0.5057234167351391,-0.01690917370953021,0.17835812614782434,-0.4569583228314796,2.0142315842992913,-0.5057234167351391,-0.2901087935675131,-0.3371883420413084,0.7407953762815624,0.3043501904123781,0.6834693746272135,-0.6047865559806115,2.777052623692763,0.945614424806558,4.027765214582355,0.447397619113444,-0.5798253703616462,-0.03909589167063334,0.005176812076117423,-0.4569583228314796,0.07084055395748909,-0.5057234167351391,-0.4569583228314796,-0.2901087935675131,2.672453216244307,0.8349190753908383,-0.36090298236806184,0.2627094020641012,0.15704238472925763,2.7380578010529537,0.9638324211451322,3.9859536481432736,1.4162109379313024,3.9859536481432736,-0.17439114903384173,1.036063009474167,-0.8619817453617755,-0.10627094673633292,2.6194057651180533,0.09253370913532158,1.000074973722675,-0.151577544698465,0.5273305006198339,0.4272126540305929,-0.24348703633272678,0.3456433744169804,-0.6804737926663148,0.13563368348203628,-1.023405807478901,-0.6298806123677426,0.19958181332532843,1.382778649014379,-1.638037942852283,-0.2901087935675131,-0.2667413189986047,-0.31359071053648363,-1.2191778402877913,-0.24348703633272678,1.3995215238872651,0.22071433819033928,-1.0784930750204527,-0.4812782346091039,-1.2766888241918128,0.3661616464083245,0.3043501904123781,0.15704238472925763,0.4272126540305929,1.000074973722675,-1.0784930750204527,0.7407953762815624,-0.22034471621492466,0.5864529093583782,0.11413110287400714,-0.22034471621492466,-0.38473594847995757,0.04905067418434559,2.6060641851362782,-0.10627094673633292 3430 Mitochondrial respiratory chain complex assembly 17 39 3.019101019451129 0.0025352598014372 Q9Y512,Q9P032,Q9BSK2,Q96CU9,P03886,Q69YU5,Q9Y2R0,Q7L592,P51970,Q9Y6M9,Q9P0J0,Q6DKK2,O43676,Q9H061,Q86Y39,Q15070,P47985 Processes and pathways GO Biological process msigdb_gobp 419,399,165,263,74,11,76,543,492,482,149,280,25,26,188,126,191 1086,25,2975,533,2387,1206,681,2438,935,839,2620,730,978,74,3112,191,492,2983,126,2837,905,11,280,543,188,911,1714,263,165,3177,26,2037,3004,399,149,1609,76,419,482 0.17835812614782434,3.8372261164826145,-0.7833273588538234,0.6060065128039738,-0.4327622425712757,0.11413110287400714,0.447397619113444,-0.4569583228314796,0.2627094020641012,0.32503982365867656,-0.5549954789805401,0.406945511095729,0.24175657929060165,2.86699521405523,-0.9151668939436284,1.5963727964305452,0.6642150900524303,-0.7833273588538234,2.1899853400179143,-0.6804737926663148,0.28357365910325655,4.282599323100913,1.1600736506845353,0.6060065128039738,1.6124494198193353,0.28357365910325655,-0.10627094673633292,1.2296215579874639,1.8171233074337798,-0.9961073484547495,3.739581024322766,-0.24348703633272678,-0.7833273588538234,0.816233531485841,1.9392759124745347,-0.061384384139230704,2.854234483045071,0.7786548166059916,0.6834693746272135 3430 Process utilizing autophagic mechanism 42 173 2.9985715182466617 0.0027124848572763 P54646,P42858,Q93050,P30536,Q9Y5X3,Q07820,P46934,P09601,P21796,Q96DM3,Q9BQS8,Q96HY6,P42574,Q15382,Q96RL7,Q9UBN7,Q96GC9,P12235,Q9BWH2,Q8IXJ6,P09429,P04062,P13473,Q86UE4,O15269,Q13315,P07602,Q7Z3C6,Q969Q5,O75844,Q9Y487,Q9NZ45,O15118,P42345,P52789,Q8TBX8,P10619,P27544,Q9NZJ7,P05141,Q99623,P16615 Processes and pathways GO Biological process msigdb_gobp 254,259,136,12,270,525,524,17,20,546,408,281,537,290,292,439,569,182,454,587,444,68,196,70,441,332,77,459,207,81,94,227,98,354,236,112,113,239,243,488,383,249 1613,2704,1367,814,1615,930,2158,98,441,1673,3149,2159,2160,785,1737,81,1787,1125,2498,1413,3193,68,2622,2863,2784,1048,488,1789,2390,77,1161,2708,2346,444,17,113,2295,182,196,2501,249,2536,2746,1630,2909,1475,3333,20,2445,239,1520,12,1094,2546,2111,354,537,259,524,2009,601,1685,1174,236,254,2716,1799,2871,2360,664,1101,1849,582,1531,2172,3056,525,1430,332,1382,2917,3240,768,2235,710,1434,290,824,825,2310,1108,1536,1183,1069,459,667,70,910,714,587,1497,2184,1713,1186,2959,112,829,1446,2132,1313,136,207,803,1231,546,2371,569,2027,281,2483,292,3318,1452,383,1769,408,1005,454,3289,1268,1008,1320,1009,923,2326,3121,3249,888,2330,2967,1873,1875,2335,227,243,3005,1989,439,1825,2491,1934,2149,2286,2253,2288,3040,1608,2700,725,1016,1827,1199,1776,1828,1273,94,1883,2382,639,698,270,1777,1778 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3430 Mitochondrial protein containing complex 43 159 2.995297500708598 0.0027417728345495 Q9NS69,Q96CU9,Q96IX5,P14406,P14854,Q9BUR5,P21796,Q9P0J0,Q567V2,O43676,Q8N4H5,O60830,P21912,O75964,Q9Y512,Q9Y5J9,Q8NE86,P13073,Q99595,P24539,P12235,Q86Y39,Q9Y584,P47985,P56385,Q7Z7H8,P03886,Q13505,Q9Y5L4,O14949,Q9Y6M9,P00403,P12236,Q14197,Q9UDW1,Q15388,Q5XKP0,Q8IYU8,P22695,P51970,Q07812,Q99623,O14925 Localization GO Cellular component msigdb_gocc 3,263,396,9,392,275,20,149,150,25,29,30,282,33,419,420,425,178,56,183,182,188,62,191,446,201,74,75,204,82,482,213,218,475,92,355,357,250,106,492,368,383,122 1086,1366,750,1941,751,122,82,25,2975,2778,30,2387,1206,3093,758,681,2438,3268,33,2259,3150,839,3215,2620,978,2293,213,74,488,536,3012,1245,1246,1948,2666,3323,1739,3297,786,182,218,178,9,392,3127,3128,3048,2296,20,282,2394,106,183,2214,3112,3113,2866,1051,1955,2001,3373,1573,191,3255,3170,3362,3256,2586,1344,492,2795,2400,2912,2588,446,820,2117,878,2873,792,1177,988,368,1485,75,475,1349,355,2837,905,666,991,797,150,1105,357,2728,585,2180,2920,201,188,1392,2314,250,29,3357,425,2993,2606,2075,263,3225,3364,396,3407,56,383,2849,634,275,1189,3032,1551,1357,3000,1981,3066,2526,2851,2375,2612,2376,1403,617,3,1321,1322,3107,1987,3037,1721,1011,149,92,1609,971,3229,2255,2616,2858,1726,2155,419,62,2618,420,204,482 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3430 Biliary tract abnormality 11 29 2.994682956855217 0.0027473023811788 P15289,Q14739,P04062,Q5XKP0,P07602,P09601,Q9NZJ7,Q14108,O43681,O95202,Q9NSD9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,311,68,357,77,17,243,22,428,154,347 1330,428,154,2345,2978,68,77,17,1518,374,2789,1522,1682,1479,2302,1298,1137,2637,22,311,357,1073,632,347,243,3142,503,1609,1728 0.04905067418434559,0.7407953762815624,1.8785482781004688,-0.40868858056019347,-0.7833273588538234,2.993031551841918,2.8157767839559593,4.05893051652828,-0.03909589167063334,0.8349190753908383,-0.6551091457204445,-0.03909589167063334,-0.10627094673633292,-0.01690917370953021,-0.38473594847995757,0.07084055395748909,0.15704238472925763,-0.5549954789805401,3.9859536481432736,1.036063009474167,0.8905672747951905,0.19958181332532843,0.5074668730496471,0.9273312549578325,1.3322253587909487,-0.9419899846973533,0.6642150900524303,-0.061384384139230704,-0.10627094673633292 3430 Mitochondrial membrane organization 18 50 2.9925644665628117 0.0027664423290088 Q9NS69,Q9Y512,Q9Y5J9,Q5XKP0,Q15070,P12235,O14737,Q13505,Q9Y5L4,P45880,P52789,O00203,P0DP25,Q07812,Q9BUR5,Q9P0J0,O95202,Q9Y584 Processes and pathways GO Biological process msigdb_gobp 3,419,420,357,126,182,329,75,204,13,236,483,304,368,275,149,154,62 483,329,1467,1368,758,3150,154,2784,488,1161,2391,304,182,3113,2215,2867,3373,3019,13,1682,2009,1479,236,368,75,126,666,991,797,357,585,1392,1973,1543,1352,275,3190,3,1321,3037,149,2149,1609,2155,419,62,2618,420,204,1201 0.6642150900524303,0.9638324211451322,-0.01690917370953021,0.027163091494653614,0.3865954317326442,-0.9689694457036316,1.8785482781004688,-0.6551091457204445,0.6642150900524303,0.13563368348203628,-0.4327622425712757,1.0539628363107982,1.6444566286616846,-0.9151668939436284,-0.3371883420413084,-0.7059762210511288,-1.5449371974827035,-0.8093982448803362,4.222429217331235,-0.10627094673633292,-0.24348703633272678,-0.01690917370953021,1.382778649014379,0.8535361731217637,2.854234483045071,2.1899853400179143,0.4675011541744141,0.24175657929060165,0.3661616464083245,0.8905672747951905,0.5471155860670778,0.027163091494653614,-0.22034471621492466,-0.03909589167063334,0.04905067418434559,1.1775484830852023,-1.023405807478901,4.706308247813215,0.07084055395748909,-0.8093982448803362,1.9392759124745347,-0.2901087935675131,-0.061384384139230704,-0.2901087935675131,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703,0.13563368348203628 3430 Disproportionate short stature 13 30 2.991690852267815 0.0027743705914797 Q15392,P42345,P16278,Q9UHX1,O95613,O15228,O00116,Q9UBN7,Q7LGA3,Q03164,Q13426,Q14739,Q96HY6 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,354,38,6,423,421,205,439,175,244,21,311,281 205,421,3069,1277,2942,1786,423,1740,38,3347,354,1250,244,21,3027,311,2596,2,880,1306,175,1395,2647,281,2030,3142,438,439,6,928 1.5152459271739311,0.7597604826477616,-0.8619817453617755,0.07084055395748909,-0.7574012545226345,-0.151577544698465,0.7597604826477616,-0.12887118746947637,3.5165359909007803,-1.3643448569490237,0.8905672747951905,0.09253370913532158,1.2982486318400348,3.9859536481432736,-0.8093982448803362,1.036063009474167,-0.5302953342350691,4.706308247813215,0.3043501904123781,0.07084055395748909,1.692107285757572,0.027163091494653614,-0.5549954789805401,1.1600736506845353,-0.24348703633272678,-0.9419899846973533,0.7407953762815624,0.7407953762815624,4.612592293772992,0.28357365910325655 3430 Endocytic vesicle membrane 8 40 2.991383115050672 0.0027771683208364 Q5T9L3,Q03519,Q8WTV0,Q93050,Q15907,Q14108,Q03518,Q9Y487 Localization GO Cellular component msigdb_gocc 192,198,71,136,111,22,86,94 1019,785,2104,1676,507,732,684,1210,413,2210,1742,196,1567,3395,491,1685,1174,1480,2871,789,2360,2677,1531,649,86,198,2266,1138,1802,22,1434,1064,111,192,71,136,1816,1452,2253,94 0.22071433819033928,0.3661616464083245,-0.2901087935675131,-0.10627094673633292,0.6448869477951056,0.406945511095729,0.447397619113444,0.11413110287400714,0.7786548166059916,-0.3371883420413084,-0.12887118746947637,1.5640718300941014,-0.061384384139230704,-1.7012045060061012,0.6642150900524303,-0.10627094673633292,0.13563368348203628,-0.01690917370953021,-0.7059762210511288,0.3661616464083245,-0.40868858056019347,-0.5798253703616462,-0.03909589167063334,0.487523996503178,2.672453216244307,1.5640718300941014,-0.36090298236806184,0.15704238472925763,-0.151577544698465,3.9859536481432736,0.005176812076117423,0.19958181332532843,2.34624122931555,1.5963727964305452,2.917749605386218,2.1174474931929272,-0.151577544698465,0.005176812076117423,-0.3371883420413084,2.6060641851362782 3430 Intrinsic component of mitochondrial membrane 20 43 2.9906441716012204 0.0027838967984952 Q9H9B4,Q9BUR5,Q16134,O60830,P57105,O43819,Q9Y512,Q8NE86,Q99595,Q9BWH2,P12235,Q13505,Q9Y2R0,Q96NB2,Q8TB36,Q15388,Q5XKP0,Q6P4A7,O14925,Q15070 Localization GO Cellular component msigdb_gocc 530,275,539,30,162,533,419,425,56,454,182,75,76,352,351,355,357,247,122,126 122,533,30,758,935,3150,937,2293,182,3373,1172,1574,162,1690,75,126,355,539,666,797,357,247,585,1392,1973,1543,425,351,352,56,275,454,3190,530,2327,2574,1321,3037,1878,2857,76,2155,419 2.233047134387105,0.6060065128039738,3.684618516209035,0.3865954317326442,0.2627094020641012,-0.9689694457036316,0.2627094020641012,-0.38473594847995757,1.6444566286616846,-1.5449371974827035,0.13563368348203628,-0.061384384139230704,1.8325459149864132,-0.10627094673633292,2.854234483045071,2.1899853400179143,0.8905672747951905,0.6060065128039738,0.4675011541744141,0.3661616464083245,0.8905672747951905,1.2811766906485145,0.5471155860670778,0.027163091494653614,-0.22034471621492466,-0.03909589167063334,0.7597604826477616,0.9089823832894932,0.9089823832894932,3.1648792186751504,1.1775484830852023,0.7217588966997998,-1.023405807478901,0.6254843056815558,-0.38473594847995757,-0.5057234167351391,0.07084055395748909,-0.8093982448803362,-0.17439114903384173,-0.6804737926663148,2.854234483045071,-0.2901087935675131,0.7786548166059916 3430 Retrograde vesicle mediated transport golgi to endoplasmic reticulum 8 27 2.9877118598391084 0.0028107440989364 P42858,P24390,O43731,Q9P2W9,Q9H4A6,Q9Y282,P18085,P49755 Processes and pathways GO Biological process msigdb_gobp 259,4,59,107,268,85,469,315 812,1275,816,1019,59,785,469,4,1341,259,1250,873,315,1029,1641,1752,1575,495,653,999,2132,1447,2029,268,107,1360,85 0.3456433744169804,0.07084055395748909,0.3456433744169804,0.22071433819033928,3.104102422844003,0.3661616464083245,0.6834693746272135,4.687680585731818,0.04905067418434559,1.2296215579874639,0.09253370913532158,0.3043501904123781,1.0181005541038732,0.22071433819033928,-0.08377571033449493,-0.12887118746947637,-0.061384384139230704,0.6642150900524303,0.487523996503178,0.24175657929060165,-0.2901087935675131,0.005176812076117423,-0.24348703633272678,1.1949644490190432,2.4019708945127647,0.04905067418434559,2.685636217276718 3430 Respirasome 15 45 2.980173908690144 0.0028808477926611 Q7KZN9,Q13423,Q96CU9,P14406,P03886,P22695,Q9UDW1,P13073,O14949,Q9P0J0,P00403,Q6DKK2,O43676,Q86Y39,P47985 Localization GO Cellular component msigdb_gocc 257,130,263,9,74,106,92,178,82,149,213,280,25,188,191 1086,1941,82,25,2975,2387,1206,3093,681,2438,839,3215,2620,978,213,74,1245,2666,1739,178,9,392,3127,3128,3048,2296,282,106,3112,2866,1051,191,3362,492,130,2837,905,280,257,188,263,149,92,1609,482 0.17835812614782434,-0.22034471621492466,2.7380578010529537,3.8372261164826145,-0.7833273588538234,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.09253370913532158,-0.5798253703616462,-0.12887118746947637,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,-0.8356157493053581,-0.38473594847995757,1.1425395010761892,2.4019708945127647,-0.9151668939436284,-0.7059762210511288,0.19958181332532843,1.5963727964305452,-1.4537345413628453,0.6642150900524303,2.1610865858455655,-0.6804737926663148,0.28357365910325655,1.1600736506845353,1.2468635762934643,1.6124494198193353,1.2296215579874639,1.9392759124745347,2.6194057651180533,-0.061384384139230704,0.6834693746272135 3430 Proton transmembrane transporter activity 12 35 2.9486251223470497 0.0031919090104075 O75964,Q13423,Q93050,P12235,P13073,P00403,P24539,Q96ES6,O95202,Q9UDW1,Q9Y487,P47985 Functions GO Molecular function msigdb_gomf 33,130,136,182,178,213,183,57,154,92,94,191 3268,33,154,213,488,536,1245,1739,182,178,392,2296,1475,3333,183,2214,1051,2001,1094,2546,191,3255,2588,446,2360,1690,130,257,136,57,2850,92,2491,94,639 -1.1623836255706177,3.5731076371518076,1.8785482781004688,1.4659622290827485,0.6642150900524303,0.6060065128039738,0.09253370913532158,-0.12887118746947637,1.6444566286616846,1.6603878760836814,0.816233531485841,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,1.6444566286616846,-0.3371883420413084,0.19958181332532843,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,1.5963727964305452,-1.1342490728645735,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.10627094673633292,2.1610865858455655,1.2468635762934643,2.1174474931929272,3.1527758461637907,-0.6804737926663148,2.6194057651180533,-0.4569583228314796,2.6060641851362782,0.5074668730496471 3430 Cis golgi network 6 16 2.9479688302104803 0.0031986931486445 O95249,P24390,O00461,Q9NPR9,O43731,Q8TBA6 Localization GO Cellular component msigdb_gocc 258,4,23,58,59,286 23,59,258,4,2262,315,1430,605,554,286,2132,1447,2029,1502,58,1082 3.9438430597865275,3.104102422844003,1.2296215579874639,4.687680585731818,-0.36090298236806184,1.0181005541038732,0.005176812076117423,0.5273305006198339,0.5864529093583782,1.1425395010761892,-0.2901087935675131,0.005176812076117423,-0.24348703633272678,-0.01690917370953021,3.1406466058440268,0.19958181332532843 3430 Abnormal biliary tract morphology 10 26 2.94332284325714 0.0032470960597728 P15289,Q14739,P04062,Q5XKP0,P07602,P09601,Q9NZJ7,Q14108,O43681,Q9NSD9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,311,68,357,77,17,243,22,428,347 1330,428,2978,68,77,17,1518,374,2789,1522,1682,1479,2302,1298,1137,22,311,357,1073,632,347,243,3142,503,1609,1728 0.04905067418434559,0.7407953762815624,-0.7833273588538234,2.993031551841918,2.8157767839559593,4.05893051652828,-0.03909589167063334,0.8349190753908383,-0.6551091457204445,-0.03909589167063334,-0.10627094673633292,-0.01690917370953021,-0.38473594847995757,0.07084055395748909,0.15704238472925763,3.9859536481432736,1.036063009474167,0.8905672747951905,0.19958181332532843,0.5074668730496471,0.9273312549578325,1.3322253587909487,-0.9419899846973533,0.6642150900524303,-0.061384384139230704,-0.10627094673633292 3430 Regulation of autophagy 30 103 2.9269859334343 0.0034226436053357 P54646,P42858,Q93050,P30536,Q9Y5X3,Q07820,P46934,P09601,P21796,Q96DM3,Q9BQS8,Q15382,Q9UBN7,P12235,P09429,P04062,Q86UE4,O15269,Q13315,P07602,O75844,Q9Y487,Q9NZ45,O15118,P42345,Q8TBX8,P10619,P27544,Q9NZJ7,P05141 Processes and pathways GO Biological process msigdb_gobp 254,259,136,12,270,525,524,17,20,546,408,290,439,182,444,68,70,441,332,77,81,94,227,98,354,112,113,239,243,488 2704,1367,814,1615,98,441,1673,3149,2159,785,1737,81,1787,1125,1413,3193,68,2622,2863,2784,1048,488,1789,2390,77,2708,2346,444,17,113,182,2501,2536,2746,1630,1475,3333,20,2445,239,12,1094,2546,2111,354,537,259,524,2009,254,2871,2360,1101,1849,582,2172,3056,525,1430,332,1382,2917,3240,768,2235,710,290,1536,1183,70,587,1497,2184,1186,2959,112,2132,136,803,546,2371,2483,3318,1452,408,1009,3249,888,2330,2967,2335,227,243,439,1825,2491,1608,725,1776,1828,94,639,270 -0.6047865559806115,0.027163091494653614,0.3456433744169804,-0.08377571033449493,2.5388692262913795,0.7217588966997998,-0.10627094673633292,-0.9689694457036316,-0.31359071053648363,0.3661616464083245,-0.12887118746947637,2.7510864124399865,-0.151577544698465,0.15704238472925763,0.005176812076117423,-1.0508669815631295,2.993031551841918,-0.5549954789805401,-0.7059762210511288,-0.6551091457204445,0.19958181332532843,0.6642150900524303,-0.151577544698465,-0.4327622425712757,2.8157767839559593,-0.6047865559806115,-0.40868858056019347,0.7217588966997998,4.05893051652828,2.3322196827838484,1.6444566286616846,-0.4812782346091039,-0.5057234167351391,-0.6298806123677426,-0.08377571033449493,-0.01690917370953021,-1.3349373118137702,3.9859536481432736,-0.4569583228314796,1.3491309609547064,4.222429217331235,0.17835812614782434,-0.5057234167351391,-0.2901087935675131,0.8905672747951905,0.6060065128039738,1.2296215579874639,0.6254843056815558,-0.24348703633272678,1.2468635762934643,-0.7059762210511288,-0.40868858056019347,0.17835812614782434,-0.17439114903384173,0.5471155860670778,-0.31359071053648363,-0.8356157493053581,0.6254843056815558,0.005176812076117423,0.9638324211451322,0.027163091494653614,-0.7316181307528602,-1.1062863390031978,0.3865954317326442,-0.3371883420413084,0.4272126540305929,1.1249455781236504,-0.03909589167063334,0.13563368348203628,2.9555165253944415,0.5471155860670778,-0.01690917370953021,-0.31359071053648363,0.13563368348203628,-0.7574012545226345,2.34624122931555,-0.2901087935675131,2.1174474931929272,0.3661616464083245,0.6060065128039738,-0.40868858056019347,-0.4569583228314796,-1.2766888241918128,0.005176812076117423,0.7974789711276091,0.24175657929060165,-1.1062863390031978,0.3043501904123781,-0.38473594847995757,-0.7574012545226345,-0.38473594847995757,1.4328472746723286,1.3322253587909487,0.7407953762815624,-0.151577544698465,-0.4569583228314796,-0.061384384139230704,0.4272126540305929,-0.12887118746947637,-0.151577544698465,2.6060641851362782,0.5074668730496471,1.1949644490190432 3430 Cation transmembrane transport 45 120 2.926647571680444 0.0034263690869382 P42858,Q13423,Q9NUT2,Q9HD20,Q9Y619,P55011,Q9H9B4,P14854,P46934,P21796,P20020,O43772,O95202,P06576,Q15043,O75964,Q9UM00,Q8NE86,P0DP25,P13073,Q96GC9,P24539,Q96ES6,P12235,Q6YHU6,P47985,P56385,Q00535,Q9P2D1,Q4KMQ2,P00403,Q9UDW1,Q96NB2,P30825,Q70HW3,P05067,P78417,Q07812,P50570,Q9UJZ1,P05141,Q99623,P16615,Q8IYU8,Q7KZN9 Processes and pathways GO Biological process msigdb_gobp 259,130,398,137,266,394,530,392,524,20,278,152,154,536,415,33,558,425,304,178,569,183,57,182,586,191,446,582,339,608,213,92,352,225,97,224,103,368,491,520,488,383,249,250,257 2738,1941,1996,152,2437,623,2387,2860,2900,3268,33,154,213,897,224,488,2665,536,3234,2785,2390,3372,2164,1245,304,1739,3236,182,178,392,249,1247,2536,2746,2667,278,2296,1475,3333,3219,20,1049,183,2214,1520,2710,3113,3076,225,1051,3348,2001,1094,2546,259,524,1374,191,3255,491,1058,2170,394,2588,446,2360,2012,1031,103,1690,582,2229,1252,368,2636,1645,130,1802,2233,1909,415,1064,1699,608,1107,586,97,257,3383,250,997,425,1352,802,57,569,2997,352,1594,3318,383,1502,1006,1150,2144,2850,530,137,924,398,339,92,1933,2491,520,558,1327,2155,266,619 -0.6298806123677426,-0.22034471621492466,-0.24348703633272678,1.8937948621783494,-0.4569583228314796,0.5074668730496471,-0.4327622425712757,-0.7059762210511288,-0.7316181307528602,-1.1623836255706177,3.5731076371518076,1.8785482781004688,1.4659622290827485,0.28357365910325655,1.4328472746723286,0.6642150900524303,-0.5798253703616462,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-0.4327622425712757,-1.5143297421023834,-0.31359071053648363,0.09253370913532158,1.0539628363107982,-0.12887118746947637,-1.1062863390031978,1.6444566286616846,1.6603878760836814,0.816233531485841,1.2640484788395443,0.09253370913532158,-0.5057234167351391,-0.6298806123677426,-0.5798253703616462,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,-1.0784930750204527,3.9859536481432736,0.19958181332532843,1.6444566286616846,-0.3371883420413084,-0.03909589167063334,-0.6047865559806115,-0.9151668939436284,-0.8619817453617755,1.4328472746723286,0.19958181332532843,-1.3643448569490237,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,1.2296215579874639,0.6254843056815558,0.027163091494653614,1.5963727964305452,-1.1342490728645735,0.6642150900524303,0.19958181332532843,-0.31359071053648363,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.24348703633272678,0.22071433819033928,2.4708459283490147,-0.10627094673633292,0.5471155860670778,-0.3371883420413084,0.09253370913532158,0.8535361731217637,-0.5549954789805401,-0.08377571033449493,2.1610865858455655,-0.151577544698465,-0.3371883420413084,-0.19731314994998111,0.7786548166059916,0.19958181332532843,-0.10627094673633292,0.5273305006198339,0.17835812614782434,0.5471155860670778,2.552373754198136,1.2468635762934643,-1.6067879521771078,1.2640484788395443,0.24175657929060165,0.7597604826477616,0.04905067418434559,0.3661616464083245,3.1527758461637907,0.5668228264787173,-0.7833273588538234,0.9089823832894932,-0.061384384139230704,-1.2766888241918128,0.8349190753908383,-0.01690917370953021,0.24175657929060165,0.15704238472925763,-0.2901087935675131,-0.6804737926663148,0.6254843056815558,2.1028225946561765,0.28357365910325655,0.816233531485841,0.945614424806558,2.6194057651180533,-0.19731314994998111,-0.4569583228314796,0.6448869477951056,0.5864529093583782,0.07084055395748909,-0.2901087935675131,1.2123219939175685,0.5273305006198339 3430 Lytic vacuole organization 9 24 2.926455899062615 0.0034284811071383 Q8N511,P04062,O14773,O75503,P50897,Q14108,P11117,P54802,P10253 Processes and pathways GO Biological process msigdb_gobp 32,68,110,116,53,22,187,124,349 483,110,116,2498,68,3011,349,187,354,53,1685,124,1346,1643,22,768,881,32,1231,3176,2483,1875,1989,3039 0.6642150900524303,2.360226918485896,2.3181620708424706,-0.4812782346091039,2.993031551841918,-0.8093982448803362,0.9089823832894932,1.6124494198193353,0.8905672747951905,3.2250123758744826,-0.10627094673633292,2.2187310778900433,0.04905067418434559,-0.08377571033449493,3.9859536481432736,0.3865954317326442,0.3043501904123781,3.6735633983186133,0.11413110287400714,-0.9961073484547495,-0.4569583228314796,-0.17439114903384173,-0.22034471621492466,-0.8093982448803362 3430 Transport of small molecules 53 154 2.914781693882735 0.0035593742557713 P35613,P30519,Q13546,P53985,Q9NUT2,Q93050,Q9HD20,P55011,P51665,P45880,P09601,P21796,P61289,Q9BU23,P20020,O95202,Q99436,Q15043,Q9Y277,Q8NE86,Q8TB61,P60900,Q9Y6B6,Q15904,Q9C0H2,Q9UBX3,P49721,P08183,P12235,Q8WTV0,P28072,P63218,Q4KMQ2,P51798,P28074,Q92530,Q9BUN8,P12236,Q9Y6M7,Q9Y487,P30825,Q99623,P20618,Q70HW3,O15118,P11166,Q9UJZ1,Q9Y5K8,Q99797,P05141,O75027,P16615,Q8IYU8 Processes and pathways Reactome Pathways msigdb_reactome 375,1,512,509,398,136,137,394,646,13,17,20,271,673,278,154,670,415,294,425,39,168,300,434,45,50,54,429,182,71,200,581,608,335,341,614,214,218,619,94,225,383,597,97,98,595,520,639,384,488,623,249,250 813,3147,1942,2619,98,700,623,2900,1785,2208,3321,2977,2104,154,1676,732,840,897,488,1566,1790,429,2164,3217,17,1740,595,182,218,2626,249,2536,2746,2213,278,663,597,1475,3333,940,20,1049,2709,982,2540,2748,2298,942,200,341,1286,1,3076,225,1955,985,1249,2353,375,2981,1342,1094,3367,2546,842,2751,13,2007,1171,54,646,335,1480,509,2170,394,2631,2716,168,271,2360,1482,1377,1898,2675,3317,2677,1900,581,2062,1531,1483,1298,3098,1966,879,512,1138,1802,1648,3337,1650,415,1699,434,608,3187,97,1494,1393,250,1265,425,39,71,1352,614,2073,136,855,1816,1594,2032,670,2423,383,384,2963,673,214,45,1598,1150,2144,2850,137,2574,3428,398,1118,50,1153,1119,2491,520,968,1937,1512,294,94,2155,639,300,619 0.3456433744169804,-0.9689694457036316,-0.22034471621492466,-0.5549954789805401,2.5388692262913795,0.4272126540305929,0.5074668730496471,-0.7316181307528602,-0.151577544698465,-0.3371883420413084,-1.3057195477388794,-0.7833273588538234,-0.2901087935675131,1.8785482781004688,-0.10627094673633292,0.406945511095729,0.32503982365867656,0.28357365910325655,0.6642150900524303,-0.061384384139230704,-0.151577544698465,0.7407953762815624,-0.31359071053648363,-1.0784930750204527,4.05893051652828,-0.12887118746947637,0.5273305006198339,1.6444566286616846,1.4494309133701686,-0.5549954789805401,1.2640484788395443,-0.5057234167351391,-0.6298806123677426,-0.3371883420413084,1.1600736506845353,0.4675011541744141,0.5273305006198339,-0.01690917370953021,-1.3349373118137702,0.2627094020641012,3.9859536481432736,0.19958181332532843,-0.6047865559806115,0.24175657929060165,-0.5057234167351391,-0.6298806123677426,-0.38473594847995757,0.2627094020641012,1.5478468035966713,0.9273312549578325,0.07084055395748909,5.005721299000376,-0.8619817453617755,1.4328472746723286,-0.22034471621492466,0.24175657929060165,0.09253370913532158,-0.40868858056019347,0.8349190753908383,-0.7833273588538234,0.04905067418434559,0.17835812614782434,-1.4839299067547875,-0.5057234167351391,0.32503982365867656,-0.6298806123677426,4.222429217331235,-0.24348703633272678,0.13563368348203628,3.1890088557974594,0.487523996503178,0.945614424806558,-0.01690917370953021,0.6448869477951056,-0.31359071053648363,0.816233531485841,-0.5549954789805401,-0.6047865559806115,1.7861436228413008,1.1775484830852023,-0.40868858056019347,-0.01690917370953021,0.027163091494653614,-0.19731314994998111,-0.5798253703616462,-1.2766888241918128,-0.5798253703616462,-0.19731314994998111,0.5471155860670778,-0.2667413189986047,-0.03909589167063334,-0.01690917370953021,0.07084055395748909,-0.8884981438055674,-0.22034471621492466,0.3043501904123781,0.6448869477951056,0.15704238472925763,-0.151577544698465,-0.08377571033449493,-1.3349373118137702,-0.08377571033449493,0.7786548166059916,-0.10627094673633292,0.7407953762815624,0.5273305006198339,-1.023405807478901,2.552373754198136,-0.01690917370953021,0.027163091494653614,1.2640484788395443,0.09253370913532158,0.7597604826477616,3.482324846985818,2.917749605386218,0.04905067418434559,0.5273305006198339,-0.2667413189986047,2.1174474931929272,0.32503982365867656,-0.151577544698465,-0.061384384139230704,-0.24348703633272678,0.4675011541744141,-0.4327622425712757,0.8349190753908383,0.8349190753908383,-0.7574012545226345,0.4675011541744141,1.4659622290827485,3.3784536775429674,-0.061384384139230704,0.15704238472925763,-0.2901087935675131,-0.6804737926663148,2.1028225946561765,-0.5057234167351391,-10.923149187726121,0.816233531485841,0.17835812614782434,3.2845170686821423,0.15704238472925763,0.17835812614782434,-0.4569583228314796,0.6448869477951056,0.2627094020641012,-0.19731314994998111,-0.01690917370953021,1.107291420206707,2.6060641851362782,-0.2901087935675131,0.5074668730496471,1.0895765601315317,0.5273305006198339 3430 Membrane lipid biosynthetic process 8 22 2.8967111918751187 0.003770967312648 Q13510,O95470,P04062,Q8NBX0,O60512,O43292,Q06136,Q96G23 Processes and pathways GO Biological process msigdb_gobp 158,64,68,135,231,177,87,61 441,1673,177,231,1998,64,68,1248,239,2460,87,158,797,135,588,2188,61,3244,834,1041,531,1876 0.7217588966997998,-0.10627094673633292,1.6603878760836814,1.3995215238872651,-0.24348703633272678,3.0426662360183325,2.993031551841918,0.09253370913532158,1.3491309609547064,-0.4569583228314796,2.672453216244307,1.8479240879335823,0.3661616464083245,2.1320329656479697,0.5471155860670778,-0.31359071053648363,3.104102422844003,-1.1062863390031978,0.3456433744169804,0.22071433819033928,0.6254843056815558,-0.17439114903384173 3430 Endoplasmic reticulum golgi intermediate compartment 18 52 2.887643108731315 0.0038813999509079 P80303,Q8N511,Q9Y3B3,P24390,Q02818,Q9BVK6,Q10472,Q03519,P09429,O15260,Q12907,Q15904,Q13190,Q15363,P49755,Q9Y282,Q03518,Q5VYK3 Localization GO Cellular component msigdb_gocc 0,32,133,4,36,427,320,198,444,319,495,434,301,241,315,85,86,540 816,319,727,1019,785,1790,444,4,3395,2262,874,315,2548,1376,2114,2359,706,0,36,86,198,1430,320,495,301,605,2724,241,434,540,995,32,1447,3140,2274,2731,569,2029,3176,2733,427,3369,1268,1822,1360,1933,1042,85,1082,133,811,1328 0.3456433744169804,1.000074973722675,0.406945511095729,0.22071433819033928,0.3661616464083245,-0.151577544698465,0.7217588966997998,4.687680585731818,-1.7012045060061012,-0.36090298236806184,0.3043501904123781,1.0181005541038732,-0.5057234167351391,0.027163091494653614,-0.2901087935675131,-0.40868858056019347,0.4272126540305929,5.333361777399175,3.527894748469767,2.672453216244307,1.5640718300941014,0.005176812076117423,1.000074973722675,0.6642150900524303,1.071800525038966,0.5273305006198339,-0.6047865559806115,1.3491309609547064,0.7407953762815624,0.6060065128039738,0.24175657929060165,3.6735633983186133,0.005176812076117423,-0.9419899846973533,-0.36090298236806184,-0.6047865559806115,0.5668228264787173,-0.24348703633272678,-0.9961073484547495,-0.6047865559806115,0.7597604826477616,-1.4839299067547875,0.09253370913532158,-0.151577544698465,0.04905067418434559,-0.19731314994998111,0.22071433819033928,2.685636217276718,0.19958181332532843,2.1610865858455655,0.3661616464083245,0.07084055395748909 3430 Endopeptidase activity 23 65 2.887098417017836 0.0038881259047331 Q16740,Q8TCT9,Q6NTF9,Q13867,P42574,P42892,P67812,P60900,O43292,P49721,Q9UPU5,Q92643,P28072,P14735,O75844,Q5JRX3,P28074,Q70CQ2,P22695,O14773,Q99797,Q14674,Q9NZ08 Functions GO Molecular function msigdb_gomf 7,274,541,402,537,161,35,168,177,54,326,588,200,330,81,609,341,358,106,110,384,513,386 110,177,2098,2900,81,2863,2390,3074,330,3280,597,106,2748,942,200,341,1954,3334,1522,2218,537,161,2301,2452,1171,54,2169,2224,2870,1751,168,35,1298,1137,402,513,2235,7,1435,1652,609,2237,541,1914,358,1584,1186,274,717,588,1815,1073,1397,916,1449,2032,670,384,3319,1664,386,326,1157,1883,2155 2.360226918485896,1.6603878760836814,-0.2901087935675131,-0.7316181307528602,2.7510864124399865,-0.7059762210511288,-0.4327622425712757,-0.8619817453617755,0.9638324211451322,-1.1906923971648218,0.5273305006198339,2.4019708945127647,-0.6298806123677426,0.2627094020641012,1.5478468035966713,0.9273312549578325,-0.22034471621492466,-1.3349373118137702,-0.03909589167063334,-0.3371883420413084,0.6060065128039738,1.8325459149864132,-0.38473594847995757,-0.4569583228314796,0.13563368348203628,3.1890088557974594,-0.31359071053648363,-0.3371883420413084,-0.7059762210511288,-0.12887118746947637,1.7861436228413008,3.527894748469767,0.07084055395748909,0.15704238472925763,0.7974789711276091,0.6448869477951056,-0.3371883420413084,4.517401396572567,0.005176812076117423,-0.08377571033449493,0.5273305006198339,-0.3371883420413084,0.6060065128039738,-0.19731314994998111,0.8905672747951905,-0.061384384139230704,0.13563368348203628,1.1775484830852023,0.4272126540305929,0.5471155860670778,-0.151577544698465,0.19958181332532843,0.027163091494653614,0.28357365910325655,0.005176812076117423,-0.24348703633272678,0.4675011541744141,0.8349190753908383,-1.2766888241918128,-0.08377571033449493,0.8349190753908383,1.000074973722675,0.15704238472925763,-0.17439114903384173,-0.2901087935675131 3430 Protein targeting 26 118 2.880783055613234 0.0039668858047627 P55786,Q9NS69,P30536,O60725,Q9P0J0,Q14108,P43307,Q8N4H5,O60830,P57105,Q9Y512,Q96RL7,Q9Y5J9,Q15041,Q9Y5M8,Q99595,Q9Y584,P13473,O14737,Q9Y5L4,Q15629,Q8TB36,Q15388,Q99797,P46379,O14925 Processes and pathways GO Biological process msigdb_gobp 128,3,12,141,149,22,28,29,30,162,419,292,420,424,180,56,62,196,329,204,89,351,355,384,121,122 1730,1995,483,815,659,329,122,930,728,428,1514,141,30,549,2900,550,3150,2820,3295,3193,730,2293,1161,2209,3398,2295,196,1630,1567,1953,2260,1520,12,2351,1893,2867,2670,842,28,121,524,874,2453,2009,1479,1685,1376,128,162,3356,2797,2718,2012,1897,1031,2676,1899,1426,582,1298,1645,766,879,22,688,424,355,89,3134,824,991,797,609,2024,1183,478,2479,3100,667,3284,2365,1394,29,351,2130,292,3287,1113,1925,633,1452,56,384,2926,833,3121,2851,963,3,1873,149,3123,1509,1154,1933,2149,2285,2288,1510,784,1828,2431,419,62,2618,420,204,180 -0.12887118746947637,-0.24348703633272678,0.6642150900524303,0.3456433744169804,0.4675011541744141,0.9638324211451322,2.233047134387105,0.2627094020641012,0.406945511095729,0.7407953762815624,-0.03909589167063334,2.0439238805196855,3.684618516209035,0.5864529093583782,-0.7316181307528602,0.5864529093583782,-0.9689694457036316,-0.6804737926663148,-1.2191778402877913,-1.0508669815631295,0.406945511095729,-0.38473594847995757,0.13563368348203628,-0.3371883420413084,-1.7976755345030844,-0.38473594847995757,1.5640718300941014,-0.08377571033449493,-0.061384384139230704,-0.22034471621492466,-0.36090298236806184,-0.03909589167063334,4.222429217331235,-0.40868858056019347,-0.19731314994998111,-0.7059762210511288,-0.5798253703616462,0.32503982365867656,3.706665868419647,2.247325615021821,0.6254843056815558,0.3043501904123781,-0.4569583228314796,-0.24348703633272678,-0.01690917370953021,-0.10627094673633292,0.027163091494653614,2.1755552047661753,1.8325459149864132,-1.4237405696271823,-0.6551091457204445,-0.6047865559806115,-0.24348703633272678,-0.19731314994998111,0.22071433819033928,-0.5798253703616462,-0.19731314994998111,0.005176812076117423,0.5471155860670778,0.07084055395748909,-0.08377571033449493,0.3865954317326442,0.3043501904123781,3.9859536481432736,0.447397619113444,0.7597604826477616,0.8905672747951905,2.632715285689517,-0.9419899846973533,0.3456433744169804,0.24175657929060165,0.3661616464083245,0.5273305006198339,-0.24348703633272678,0.13563368348203628,0.6834693746272135,-0.4569583228314796,-0.8884981438055674,0.4675011541744141,-1.1906923971648218,-0.40868858056019347,0.027163091494653614,3.706665868419647,0.9089823832894932,-0.2901087935675131,1.1249455781236504,-1.1906923971648218,0.17835812614782434,-0.19731314994998111,0.5074668730496471,0.005176812076117423,3.1648792186751504,0.8349190753908383,-0.7316181307528602,0.3456433744169804,-0.9151668939436284,-0.6804737926663148,0.2627094020641012,4.706308247813215,-0.17439114903384173,1.9392759124745347,-0.9151668939436284,-0.01690917370953021,0.15704238472925763,-0.19731314994998111,-0.2901087935675131,-0.36090298236806184,-0.36090298236806184,-0.01690917370953021,0.3865954317326442,-0.151577544698465,-0.4327622425712757,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703,1.6603878760836814 3430 Establishment of protein localization to membrane 25 89 2.8729943119029797 0.0040660143700477 Q9NS69,Q13277,Q9HD20,O60725,Q9H4A6,Q9P0J0,P43307,Q9Y512,Q9Y5J9,Q15041,Q15904,P0DP25,O43681,Q96A33,Q9Y584,O14737,Q9Y5L4,Q7L5D6,Q15629,O15118,O00203,Q15907,Q07812,P46379,Q15070 Processes and pathways GO Biological process msigdb_gobp 3,260,137,141,268,149,28,419,420,424,434,304,428,323,62,329,204,478,89,98,483,111,368,121,126 1730,483,815,329,2158,98,428,1514,141,2388,550,3150,1788,1161,2209,304,1953,2215,2351,2867,2670,842,1795,28,121,2505,2453,1479,1685,1345,3356,2871,2718,789,2012,2635,582,1532,368,1645,766,260,3271,3282,424,710,126,89,434,111,1652,797,1702,478,3284,2365,1394,2242,1712,2130,1352,323,2483,1113,1009,268,2325,3121,137,519,963,3,1873,1195,149,1509,1154,1933,1462,2530,1510,1198,1609,2431,419,62,2618,420,204 -0.12887118746947637,0.6642150900524303,0.3456433744169804,0.9638324211451322,-0.31359071053648363,2.5388692262913795,0.7407953762815624,-0.03909589167063334,2.0439238805196855,-0.4327622425712757,0.5864529093583782,-0.9689694457036316,-0.151577544698465,0.13563368348203628,-0.3371883420413084,1.0539628363107982,-0.22034471621492466,-0.3371883420413084,-0.40868858056019347,-0.7059762210511288,-0.5798253703616462,0.32503982365867656,-0.151577544698465,3.706665868419647,2.247325615021821,-0.4812782346091039,-0.4569583228314796,-0.01690917370953021,-0.10627094673633292,0.04905067418434559,-1.4237405696271823,-0.7059762210511288,-0.6047865559806115,0.3661616464083245,-0.24348703633272678,-0.5549954789805401,0.5471155860670778,-0.03909589167063334,0.8535361731217637,-0.08377571033449493,0.3865954317326442,1.2296215579874639,-1.1623836255706177,-1.1906923971648218,0.7597604826477616,0.4272126540305929,2.1899853400179143,2.632715285689517,0.7407953762815624,2.34624122931555,-0.08377571033449493,0.3661616464083245,-0.10627094673633292,0.6834693746272135,-1.1906923971648218,-0.40868858056019347,0.027163091494653614,-0.3371883420413084,-0.10627094673633292,-0.2901087935675131,0.04905067418434559,1.000074973722675,-0.4569583228314796,0.17835812614782434,0.24175657929060165,1.1949644490190432,-0.38473594847995757,-0.9151668939436284,2.1028225946561765,0.6448869477951056,0.2627094020641012,4.706308247813215,-0.17439114903384173,0.13563368348203628,1.9392759124745347,-0.01690917370953021,0.15704238472925763,-0.19731314994998111,0.005176812076117423,-0.4812782346091039,-0.01690917370953021,0.13563368348203628,-0.061384384139230704,-0.4327622425712757,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Organic anion transmembrane transporter activity 15 28 2.8697849847524566 0.0041075100400296 P53985,Q8TB61,Q9Y619,Q9H9B4,Q9UBX3,O43808,Q9BQT8,Q14728,P05141,Q9H2D1,P12236,P12235,Q96NB2,P30825,Q9Y6M7 Functions GO Molecular function msigdb_gomf 509,39,266,530,50,486,409,565,488,120,218,182,352,225,619 486,1369,937,488,2164,595,182,218,225,1290,509,739,565,1699,1182,3187,1393,39,352,2963,409,120,2850,530,50,967,266,619 0.6642150900524303,0.027163091494653614,0.2627094020641012,0.6642150900524303,-0.31359071053648363,0.5273305006198339,1.6444566286616846,1.4494309133701686,1.4328472746723286,0.07084055395748909,0.6448869477951056,0.406945511095729,0.5668228264787173,-0.10627094673633292,0.13563368348203628,-1.023405807478901,0.027163091494653614,3.482324846985818,0.9089823832894932,-0.7574012545226345,0.7974789711276091,2.2615667415404976,-0.6804737926663148,0.6254843056815558,3.2845170686821423,0.2627094020641012,1.2123219939175685,0.5273305006198339 3430 Protein targeting to mitochondrion 15 46 2.867961203230733 0.0041312618946904 P55786,Q8TB36,Q9NS69,Q9Y512,Q15388,O14737,P30536,Q9Y5L4,Q9P0J0,Q99797,Q99595,Q9Y584,O14925,Q8N4H5,O60830 Processes and pathways GO Biological process msigdb_gobp 128,351,3,419,355,329,12,204,149,384,56,62,122,29,30 1995,329,122,728,30,2900,3150,2820,3295,3193,730,2293,1161,3398,1630,12,2867,874,2009,1376,128,1426,1298,355,3134,991,797,609,667,29,351,1925,56,384,833,2851,3,149,3123,2149,1828,419,62,2618,420,204 -0.24348703633272678,0.9638324211451322,2.233047134387105,0.406945511095729,3.684618516209035,-0.7316181307528602,-0.9689694457036316,-0.6804737926663148,-1.2191778402877913,-1.0508669815631295,0.406945511095729,-0.38473594847995757,0.13563368348203628,-1.7976755345030844,-0.08377571033449493,4.222429217331235,-0.7059762210511288,0.3043501904123781,-0.24348703633272678,0.027163091494653614,2.1755552047661753,0.005176812076117423,0.07084055395748909,0.8905672747951905,-0.9419899846973533,0.24175657929060165,0.3661616464083245,0.5273305006198339,0.4675011541744141,3.706665868419647,0.9089823832894932,-0.19731314994998111,3.1648792186751504,0.8349190753908383,0.3456433744169804,-0.6804737926663148,4.706308247813215,1.9392759124745347,-0.9151668939436284,-0.2901087935675131,-0.151577544698465,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Membrane organization 65 227 2.856355218885162 0.0042853539729608 Q15392,Q9NS69,O95249,Q13277,P30536,P45880,Q86XL3,Q9H4A6,Q9BUR5,Q9P0J0,O95202,Q8NHH9,O75955,O15400,Q9Y512,Q9Y5J9,Q15041,Q9BVK6,Q9Y6B6,Q14849,O15228,Q13190,P0DP25,P49354,Q96GC9,P50897,P08183,P43034,O43681,P12235,O95487,P49755,Q9Y584,Q8IXJ6,Q96A33,Q8NFQ8,Q9H5V9,Q6UXV4,O14737,Q13505,Q9Y5L4,Q7Z3C6,O94901,O75844,Q7L5D6,Q15629,Q9UQB8,O15118,P57088,P16615,Q5XKP0,Q9P2W9,P52789,O00203,Q15363,Q07812,P50570,Q9NZJ7,P05141,Q9NR31,P46379,Q9NPA0,Q9BTV4,Q15070,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 2,3,258,260,12,13,140,268,275,149,154,416,534,532,419,420,424,427,300,43,421,301,304,306,569,53,429,564,428,182,561,315,62,587,323,193,590,585,329,75,204,459,574,81,478,89,93,98,493,249,357,107,236,483,241,368,491,243,488,248,121,519,517,126,127 483,1367,814,1672,2739,659,2740,329,930,1779,2158,98,421,816,532,727,428,1514,1467,661,2343,1784,1368,1674,2160,785,758,3313,3180,81,534,3150,2103,574,2781,154,2903,258,1889,2498,1208,561,2978,1890,2784,488,1335,2785,1161,3372,429,2346,2391,304,2295,182,249,1247,2536,2908,3253,2668,1248,3113,2215,12,2867,1477,3373,2299,3019,564,13,3335,121,2505,1682,873,306,315,2009,600,1479,491,53,1685,3153,1174,236,987,2673,2796,493,3183,1845,2871,2798,2012,1482,664,1689,1380,1576,1532,649,2460,368,1381,1645,2985,301,260,2512,75,1255,989,1142,768,3027,43,3282,424,126,3158,1698,2018,1064,241,2,990,89,666,991,608,3386,797,1702,1703,2882,357,585,478,459,667,140,714,3284,1392,1973,1543,587,1585,1394,853,2242,3387,3329,193,416,829,2318,1446,1352,1447,3119,3140,2844,2369,323,1816,3102,569,1593,2693,2323,517,275,427,746,2034,1008,3190,268,590,695,1820,519,127,2250,248,3415,3,1321,1875,3037,243,3005,1195,149,1876,1824,107,3412,1406,1933,2149,2615,2737,3007,2288,2200,1121,2700,93,1609,1361,2935,1828,2155,419,62,2618,420,204,2384,1201,300 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3430 Abnormality of femur morphology 22 74 2.8537870350116497 0.0043201481242687 Q9UHX1,P55011,Q9Y619,P06280,P51812,Q96HY6,P16278,Q7LGA3,P16435,Q14739,O15360,Q96A33,P04062,P07602,O00116,Q9P2D1,O75844,P51798,Q9Y487,Q96L58,Q96AY3,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 6,394,266,389,19,281,38,175,310,311,308,323,68,77,205,339,81,335,94,234,366,243 205,814,2818,1560,1087,308,1277,1204,2942,758,1786,81,2782,423,730,1738,2978,68,2582,2784,389,2945,77,1126,38,310,3219,643,1476,2503,1288,3373,3335,1250,1479,335,19,2400,394,2718,311,2596,1222,880,653,3081,175,2478,3387,1395,3175,2320,323,366,2647,281,234,1036,671,1039,887,2035,2895,2573,1116,243,339,6,2253,1408,2340,94,1364,266 1.5152459271739311,0.3456433744169804,-0.6804737926663148,-0.061384384139230704,0.17835812614782434,1.036063009474167,0.07084055395748909,0.11413110287400714,-0.7574012545226345,0.3865954317326442,-0.151577544698465,2.7510864124399865,-0.6551091457204445,0.7597604826477616,0.406945511095729,-0.12887118746947637,-0.7833273588538234,2.993031551841918,-0.5302953342350691,-0.6551091457204445,0.816233531485841,-0.7574012545226345,2.8157767839559593,0.15704238472925763,3.5165359909007803,1.036063009474167,-1.0784930750204527,0.487523996503178,-0.01690917370953021,-0.4812782346091039,0.07084055395748909,-1.5449371974827035,-1.3349373118137702,0.09253370913532158,-0.01690917370953021,0.945614424806558,4.027765214582355,-0.4327622425712757,0.816233531485841,-0.6047865559806115,1.036063009474167,-0.5302953342350691,0.11413110287400714,0.3043501904123781,0.487523996503178,-0.8619817453617755,1.692107285757572,-0.4569583228314796,-1.638037942852283,0.027163091494653614,-0.9961073484547495,-0.38473594847995757,1.000074973722675,0.872085387655934,-0.5549954789805401,1.1600736506845353,1.3995215238872651,0.22071433819033928,0.4675011541744141,0.22071433819033928,0.3043501904123781,-0.24348703633272678,-0.7059762210511288,-0.5057234167351391,0.17835812614782434,1.3322253587909487,0.945614424806558,4.612592293772992,-0.3371883420413084,0.027163091494653614,-0.38473594847995757,2.6060641851362782,0.04905067418434559,1.2123219939175685 3430 Glycosaminoglycan metabolism 6 15 2.8530391701665256 0.0043303283574847 P16278,O60512,Q8TB61,Q96L58,Q7LGA3,P54802 Processes and pathways Reactome Pathways msigdb_reactome 38,231,39,234,175,124 1159,246,231,1624,1336,3011,1415,642,38,124,175,39,234,1933,557 0.13563368348203628,1.2811766906485145,1.3995215238872651,-0.08377571033449493,0.04905067418434559,-0.8093982448803362,0.005176812076117423,0.487523996503178,3.5165359909007803,2.2187310778900433,1.692107285757572,3.482324846985818,1.3995215238872651,-0.19731314994998111,0.5864529093583782 3430 Mitochondrial protein import 10 36 2.83854452092686 0.0045319796668084 Q9NS69,O14925,Q13505,Q9Y5L4,P21796,Q99595,Q9Y584,P12235,Q8N4H5,O60830 Processes and pathways Reactome Pathways msigdb_reactome 3,122,75,204,20,56,62,182,29,30 122,728,30,3267,758,2900,1369,3150,2293,536,1245,3398,182,218,20,2214,3373,1344,1298,75,355,991,609,29,56,3227,2851,3,3037,967,1609,419,62,2618,420,204 2.233047134387105,0.406945511095729,3.684618516209035,-1.1623836255706177,0.3865954317326442,-0.7316181307528602,0.027163091494653614,-0.9689694457036316,-0.38473594847995757,0.6060065128039738,0.09253370913532158,-1.7976755345030844,1.6444566286616846,1.4494309133701686,3.9859536481432736,-0.3371883420413084,-1.5449371974827035,0.04905067418434559,0.07084055395748909,2.854234483045071,0.8905672747951905,0.24175657929060165,0.5273305006198339,3.706665868419647,3.1648792186751504,-1.0784930750204527,-0.6804737926663148,4.706308247813215,-0.8093982448803362,0.2627094020641012,-0.061384384139230704,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Inorganic anion transport 11 25 2.819704948609576 0.0048067824497255 Q9UHG3,Q9Y277,P55011,P30536,P45880,Q9C0H2,Q9UBX3,P51798,P21796,P08183,Q15043 Processes and pathways GO Biological process msigdb_gobp 100,294,394,12,13,45,50,335,20,429,415 2859,428,429,2049,20,12,13,335,901,394,1690,739,415,608,3368,1393,1038,1006,45,2033,50,100,294,3330,619 -0.7059762210511288,0.7407953762815624,0.7407953762815624,-0.2667413189986047,3.9859536481432736,4.222429217331235,4.222429217331235,0.945614424806558,0.28357365910325655,0.816233531485841,-0.10627094673633292,0.406945511095729,0.7786548166059916,0.5273305006198339,-1.4839299067547875,0.027163091494653614,0.22071433819033928,0.24175657929060165,3.3784536775429674,-0.24348703633272678,3.2845170686821423,2.5388692262913795,1.107291420206707,-1.3057195477388794,0.5273305006198339 3430 Glycosphingolipid metabolism 9 16 2.8185423316210807 0.0048242249322889 Q13510,P15289,P04062,P16278,P17900,P07602,P06280,P10619,Q9NZJ7 Processes and pathways Reactome Pathways msigdb_reactome 158,374,68,38,104,77,389,113,243 1241,428,68,389,1336,77,3011,113,374,38,104,158,2522,2524,1041,243 0.09253370913532158,0.7407953762815624,2.993031551841918,0.816233531485841,0.04905067418434559,2.8157767839559593,-0.8093982448803362,2.3322196827838484,0.8349190753908383,3.5165359909007803,2.4571398271524862,1.8479240879335823,-0.4812782346091039,-0.4812782346091039,0.22071433819033928,1.3322253587909487 3430 Sphingolipid biosynthetic process 6 15 2.816749265724466 0.0048512381928851 Q13510,O95470,P04062,O60512,Q06136,Q96G23 Processes and pathways GO Biological process msigdb_gobp 158,64,68,231,87,61 441,1673,231,64,68,1248,239,2460,87,158,797,61,1041,531,1876 0.7217588966997998,-0.10627094673633292,1.3995215238872651,3.0426662360183325,2.993031551841918,0.09253370913532158,1.3491309609547064,-0.4569583228314796,2.672453216244307,1.8479240879335823,0.3661616464083245,3.104102422844003,0.22071433819033928,0.6254843056815558,-0.17439114903384173 3430 Endoplasmic reticulum golgi intermediate compartment membrane 13 26 2.812821646207749 0.0049108881432249 Q8N511,Q9Y3B3,P24390,Q10472,Q9BVK6,Q03519,O15260,Q15904,Q13190,Q15363,Q9Y282,Q03518,P49755 Localization GO Cellular component msigdb_gocc 32,133,4,320,427,198,319,434,301,241,85,86,315 319,727,1019,785,4,3395,874,315,1376,706,86,198,1430,320,495,301,241,434,32,569,427,3369,1268,85,1082,133 1.000074973722675,0.406945511095729,0.22071433819033928,0.3661616464083245,4.687680585731818,-1.7012045060061012,0.3043501904123781,1.0181005541038732,0.027163091494653614,0.4272126540305929,2.672453216244307,1.5640718300941014,0.005176812076117423,1.000074973722675,0.6642150900524303,1.071800525038966,1.3491309609547064,0.7407953762815624,3.6735633983186133,0.5668228264787173,0.7597604826477616,-1.4839299067547875,0.09253370913532158,2.685636217276718,0.19958181332532843,2.1610865858455655 3430 Hydrolase activity acting on glycosyl bonds 9 30 2.811704094766979 0.0049279815554272 O60502,P04062,P16278,P17900,Q9BTY2,Q9NUJ1,O75503,P54802,P10253 Functions GO Molecular function msigdb_gomf 223,68,38,104,361,78,116,124,349 1560,1020,621,223,116,68,2582,389,1336,3011,1415,349,2500,1127,38,104,1841,1520,841,124,951,1487,1907,554,2991,2413,2522,361,78,2380 -0.061384384139230704,0.22071433819033928,0.5074668730496471,1.4328472746723286,2.3181620708424706,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,-0.8093982448803362,0.005176812076117423,0.9089823832894932,-0.4812782346091039,0.15704238472925763,3.5165359909007803,2.4571398271524862,-0.17439114903384173,-0.03909589167063334,0.32503982365867656,2.2187310778900433,0.2627094020641012,-0.01690917370953021,-0.19731314994998111,0.5864529093583782,-0.7833273588538234,-0.4327622425712757,-0.4812782346091039,0.8905672747951905,2.789990541137051,-0.40868858056019347 3430 Organophosphate ester transport 12 25 2.807411489258559 0.0049941402036723 Q9BSK2,Q8WTV0,Q8TB61,Q7Z3C6,O43808,Q96GC9,P05141,Q14108,P08183,Q9H2D1,P12236,P12235 Processes and pathways GO Biological process msigdb_gobp 165,71,39,459,486,569,488,22,429,120,218,182 2739,486,488,429,182,218,1248,2538,873,1482,2460,22,608,1182,459,1393,39,71,569,2963,165,746,2034,120,1876 -0.6298806123677426,0.6642150900524303,0.6642150900524303,0.7407953762815624,1.6444566286616846,1.4494309133701686,0.09253370913532158,-0.5057234167351391,0.3043501904123781,-0.01690917370953021,-0.4569583228314796,3.9859536481432736,0.5273305006198339,0.13563368348203628,0.7026504351173741,0.027163091494653614,3.482324846985818,2.917749605386218,0.5668228264787173,-0.7574012545226345,1.8171233074337798,0.406945511095729,-0.24348703633272678,2.2615667415404976,-0.17439114903384173 3430 Steroid biosynthetic process 14 49 2.7993556526415757 0.005120470468144 P54646,Q13510,Q15392,O76062,Q15800,Q53GQ0,Q14849,P30536,Q14534,Q16850,P48449,P16435,Q14739,P37268 Processes and pathways GO Biological process msigdb_gobp 254,158,2,164,101,202,43,12,272,146,184,310,311,123 2434,678,1785,468,164,2977,1677,897,3236,1128,2788,310,1248,2538,2790,1286,12,123,3019,184,1637,3418,254,2632,3156,158,3132,272,311,43,2725,2,1968,1911,1259,101,146,202,998,2371,1315,2849,2696,324,2034,1666,438,1605,1119 -0.4569583228314796,0.447397619113444,-0.151577544698465,0.6834693746272135,1.8171233074337798,-0.7833273588538234,-0.10627094673633292,0.28357365910325655,-1.1062863390031978,0.15704238472925763,-0.6551091457204445,1.036063009474167,0.09253370913532158,-0.5057234167351391,-0.6551091457204445,0.07084055395748909,4.222429217331235,2.2187310778900433,-0.8093982448803362,1.6444566286616846,-0.08377571033449493,-2.614938713691235,1.2468635762934643,-0.5549954789805401,-0.9689694457036316,1.8479240879335823,-0.9419899846973533,1.1775484830852023,1.036063009474167,3.413286496271575,-0.6047865559806115,4.706308247813215,-0.22034471621492466,-0.19731314994998111,0.09253370913532158,2.5117605953310402,2.0142315842992913,1.5315716196659703,0.24175657929060165,-0.40868858056019347,0.07084055395748909,-0.6804737926663148,-0.5798253703616462,1.000074973722675,-0.24348703633272678,-0.08377571033449493,0.7407953762815624,-0.061384384139230704,0.17835812614782434 3430 Hormone metabolic process 11 29 2.795706497579628 0.0051786406745728 O95470,P42892,Q53GQ0,Q14849,P30536,P14735,Q06520,O75844,Q9HB40,P16435,Q6NUM9 Processes and pathways GO Biological process msigdb_gobp 64,161,202,43,12,330,174,81,55,310,380 1782,81,640,64,897,330,2788,310,12,1343,161,3052,2302,2632,2119,174,43,1911,202,380,716,998,912,2997,2849,55,438,3040,638 -0.151577544698465,2.7510864124399865,0.487523996503178,3.0426662360183325,0.28357365910325655,0.9638324211451322,-0.6551091457204445,1.036063009474167,4.222429217331235,0.04905067418434559,1.8325459149864132,-0.8356157493053581,-0.38473594847995757,-0.5549954789805401,-0.2901087935675131,1.7078960893112645,3.413286496271575,-0.19731314994998111,1.5315716196659703,0.8349190753908383,0.4272126540305929,0.24175657929060165,0.28357365910325655,-0.7833273588538234,-0.6804737926663148,3.1769568474904344,0.7407953762815624,-0.8093982448803362,0.5074668730496471 3430 Protease 19 84 2.790488565978257 0.0052628559067466 P55786,Q16740,Q9UIQ6,Q8TCT9,P42892,P67812,P42785,Q9H3G5,Q9HB40,Q9UPU5,P28072,P14735,O75844,P28074,Q70CQ2,O14773,P10619,Q99797,Q9NZ08 Functions Protein Atlas Molecular function protein_atlas_molecular_function 128,7,143,274,161,35,47,49,55,326,200,330,81,341,358,110,113,384,386 1409,1942,110,2098,2900,81,936,2292,1209,2390,1337,113,3097,330,3280,200,341,3298,1954,1522,2218,537,47,161,2301,2452,2828,2169,2224,2587,2870,1751,128,2797,35,1965,402,513,2235,688,7,1435,1652,609,2237,1491,1914,358,3174,909,1584,1186,274,588,1815,1073,1397,2888,1592,515,916,804,1449,2032,670,3318,384,1664,49,2248,1235,1819,55,3106,2613,2090,386,143,326,892,1157,1883,2155,2899 0.005176812076117423,-0.22034471621492466,2.360226918485896,-0.2901087935675131,-0.7316181307528602,2.7510864124399865,0.2627094020641012,-0.38473594847995757,0.11413110287400714,-0.4327622425712757,0.04905067418434559,2.3322196827838484,-0.8884981438055674,0.9638324211451322,-1.1906923971648218,1.5478468035966713,0.9273312549578325,-1.2191778402877913,-0.22034471621492466,-0.03909589167063334,-0.3371883420413084,0.6060065128039738,3.3551136813137883,1.8325459149864132,-0.38473594847995757,-0.4569583228314796,-0.6804737926663148,-0.31359071053648363,-0.3371883420413084,-0.5302953342350691,-0.7059762210511288,-0.12887118746947637,2.1755552047661753,-0.6551091457204445,3.527894748469767,-0.22034471621492466,0.7974789711276091,0.6448869477951056,-0.3371883420413084,0.447397619113444,4.517401396572567,0.005176812076117423,-0.08377571033449493,0.5273305006198339,-0.3371883420413084,-0.01690917370953021,-0.19731314994998111,0.8905672747951905,-0.9961073484547495,0.28357365910325655,-0.061384384139230704,0.13563368348203628,1.1775484830852023,0.5471155860670778,-0.151577544698465,0.19958181332532843,0.027163091494653614,-0.7059762210511288,-0.061384384139230704,0.6448869477951056,0.28357365910325655,0.3661616464083245,0.005176812076117423,-0.24348703633272678,0.4675011541744141,-1.2766888241918128,0.8349190753908383,-0.08377571033449493,3.3551136813137883,-0.3371883420413084,0.11413110287400714,-0.151577544698465,3.1769568474904344,-0.8884981438055674,-0.5302953342350691,-0.2667413189986047,0.8349190753908383,2.0290981867058675,1.000074973722675,0.3043501904123781,0.15704238472925763,-0.17439114903384173,-0.2901087935675131,-0.7059762210511288 3430 Ceramide metabolic process 9 18 2.7897977425887377 0.0052740977584802 Q13510,O95470,P04062,O60512,P17900,P06280,P27544,Q8NCC3,Q96G23 Processes and pathways GO Biological process msigdb_gobp 158,64,68,231,104,389,239,84,61 441,1673,231,64,68,389,1336,3011,104,239,2261,2460,158,797,84,61,2522,1041 0.7217588966997998,-0.10627094673633292,1.3995215238872651,3.0426662360183325,2.993031551841918,0.816233531485841,0.04905067418434559,-0.8093982448803362,2.4571398271524862,1.3491309609547064,-0.36090298236806184,-0.4569583228314796,1.8479240879335823,0.3661616464083245,2.6987880108067723,3.104102422844003,-0.4812782346091039,0.22071433819033928 3430 Parkinsons disease 15 55 2.789047505176507 0.0052863310276958 P47985,P12236,P14406,P03886,P22695,P45880,P13073,O14949,P21796,P00403,P24539,O43676,P12235,Q9UDW1,P21912 Processes and pathways KEGG Pathways msigdb_kegg 191,218,9,74,106,13,178,82,20,213,183,25,182,92,282 1086,1941,82,25,2975,2387,1206,3093,681,2438,3268,839,3215,2620,978,213,74,488,536,1245,2666,1739,182,218,178,9,392,3127,3128,3048,2296,20,282,2109,106,183,2214,3112,2866,1051,2001,537,13,191,3255,3362,492,1426,2554,2837,905,3318,92,294,482 0.17835812614782434,-0.22034471621492466,2.7380578010529537,3.8372261164826145,-0.7833273588538234,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,-1.1623836255706177,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.6642150900524303,0.6060065128039738,0.09253370913532158,-0.5798253703616462,-0.12887118746947637,1.6444566286616846,1.4494309133701686,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,-0.8356157493053581,-0.38473594847995757,3.9859536481432736,1.1425395010761892,-0.2901087935675131,2.4019708945127647,1.6444566286616846,-0.3371883420413084,-0.9151668939436284,-0.7059762210511288,0.19958181332532843,-0.24348703633272678,0.6060065128039738,4.222429217331235,1.5963727964305452,-1.1342490728645735,-1.4537345413628453,0.6642150900524303,0.005176812076117423,-0.5057234167351391,-0.6804737926663148,0.28357365910325655,-1.2766888241918128,2.6194057651180533,1.107291420206707,0.6834693746272135 3430 Protein transporter activity 8 15 2.788618849992371 0.0052933321207131 Q15388,Q9NS69,Q9HD20,Q99595,Q9Y584,O14925,P49755,O60830 Functions GO Molecular function msigdb_gomf 355,3,137,56,62,122,315,30 122,30,3150,2293,315,2012,525,355,1712,56,137,3,1509,62,420 2.233047134387105,3.684618516209035,-0.9689694457036316,-0.38473594847995757,1.0181005541038732,-0.24348703633272678,0.6254843056815558,0.8905672747951905,-0.10627094673633292,3.1648792186751504,2.1028225946561765,4.706308247813215,-0.01690917370953021,3.0796079772709244,0.7786548166059916 3430 Vacuole organization 11 53 2.7796585555437416 0.0054416081267278 Q8N511,P04062,O14773,Q8TBX8,O75503,P50897,Q14108,P16615,P11117,P54802,P10253 Processes and pathways GO Biological process msigdb_gobp 32,68,110,112,116,53,22,249,187,124,349 483,110,785,116,1125,2498,1413,3193,68,2785,3011,349,187,249,354,601,53,1685,124,1799,1346,664,1643,22,768,710,1434,554,881,1108,459,714,32,112,2132,1231,569,3176,2483,1268,1320,1009,1873,1875,1989,3039,2253,2288,2700,1199,1828,1883,2382 0.6642150900524303,2.360226918485896,0.3661616464083245,2.3181620708424706,0.15704238472925763,-0.4812782346091039,0.005176812076117423,-1.0508669815631295,2.993031551841918,-0.6551091457204445,-0.8093982448803362,0.9089823832894932,1.6124494198193353,1.2640484788395443,0.8905672747951905,0.5273305006198339,3.2250123758744826,-0.10627094673633292,2.2187310778900433,-0.151577544698465,0.04905067418434559,0.4675011541744141,-0.08377571033449493,3.9859536481432736,0.3865954317326442,0.4272126540305929,0.005176812076117423,0.5864529093583782,0.3043501904123781,0.17835812614782434,0.7026504351173741,0.4272126540305929,3.6735633983186133,2.34624122931555,-0.2901087935675131,0.11413110287400714,0.5668228264787173,-0.9961073484547495,-0.4569583228314796,0.09253370913532158,0.07084055395748909,0.24175657929060165,-0.17439114903384173,-0.17439114903384173,-0.22034471621492466,-0.8093982448803362,-0.3371883420413084,-0.36090298236806184,-0.5798253703616462,0.13563368348203628,-0.151577544698465,-0.17439114903384173,-0.40868858056019347 3430 Endoplasmic reticulum organization 15 43 2.775946314111001 0.005504129623955 Q8NHH9,Q8NFQ8,P46379,P57088,Q15041,O95197,Q9P2W9,Q12907,Q15363,Q8N5M9,Q7L5D6,O43681,Q15629,Q96A33,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 416,193,121,493,424,42,107,495,241,210,478,428,89,323,127 1241,3214,1367,1779,2158,428,1514,2781,42,1889,121,874,1479,493,789,2012,1576,495,3282,424,710,241,89,1702,1703,3274,478,210,2242,193,416,323,2524,1457,1009,590,1871,519,127,1041,1195,1876,107 0.09253370913532158,-1.0784930750204527,0.027163091494653614,-0.151577544698465,-0.31359071053648363,0.7407953762815624,-0.03909589167063334,-0.6551091457204445,3.4479092742401036,-0.19731314994998111,2.247325615021821,0.3043501904123781,-0.01690917370953021,0.6642150900524303,0.3661616464083245,-0.24348703633272678,-0.061384384139230704,0.6642150900524303,-1.1906923971648218,0.7597604826477616,0.4272126540305929,1.3491309609547064,2.632715285689517,-0.10627094673633292,-0.10627094673633292,-1.1623836255706177,0.6834693746272135,1.4988693711510455,-0.3371883420413084,1.5963727964305452,0.7786548166059916,1.000074973722675,-0.4812782346091039,0.005176812076117423,0.24175657929060165,0.5471155860670778,-0.17439114903384173,0.6448869477951056,2.1899853400179143,0.22071433819033928,0.13563368348203628,-0.17439114903384173,2.4019708945127647 3430 Regulation of hormone levels 17 68 2.7665774182839606 0.0056648132601446 O95470,P42892,Q16836,Q8NE86,Q53GQ0,Q14849,P30536,P14735,Q06520,Q9P2D1,Q15907,O75844,Q8N5M9,Q9HB40,P16435,Q6NUM9,Q15043 Processes and pathways GO Biological process msigdb_gobp 64,161,356,425,202,43,12,330,174,339,111,81,210,55,310,380,415 2043,1366,2739,1331,755,1833,1782,81,640,1125,64,937,1947,840,1890,897,1469,330,2788,310,1519,1248,12,3076,1573,1343,161,3052,1574,2302,1174,509,3237,2632,664,1902,2119,174,2462,1138,43,415,1911,111,2267,356,202,380,2024,3082,1393,911,210,716,998,425,912,2997,2135,1451,3318,2849,55,339,438,3040,1608,638 -0.2667413189986047,0.027163091494653614,-0.6298806123677426,0.04905067418434559,0.3865954317326442,-0.17439114903384173,-0.151577544698465,2.7510864124399865,0.487523996503178,0.15704238472925763,3.0426662360183325,0.2627094020641012,-0.22034471621492466,0.32503982365867656,-0.19731314994998111,0.28357365910325655,-0.01690917370953021,0.9638324211451322,-0.6551091457204445,1.036063009474167,-0.03909589167063334,0.09253370913532158,4.222429217331235,-0.8619817453617755,-0.061384384139230704,0.04905067418434559,1.8325459149864132,-0.8356157493053581,-0.061384384139230704,-0.38473594847995757,0.13563368348203628,0.6448869477951056,-1.1062863390031978,-0.5549954789805401,0.4675011541744141,-0.19731314994998111,-0.2901087935675131,1.7078960893112645,-0.4569583228314796,0.15704238472925763,3.413286496271575,0.7786548166059916,-0.19731314994998111,2.34624122931555,-0.36090298236806184,0.8905672747951905,1.5315716196659703,0.8349190753908383,-0.24348703633272678,-0.8619817453617755,0.027163091494653614,0.28357365910325655,1.4988693711510455,0.4272126540305929,0.24175657929060165,0.7597604826477616,0.28357365910325655,-0.7833273588538234,-0.2901087935675131,0.005176812076117423,-1.2766888241918128,-0.6804737926663148,3.1769568474904344,0.945614424806558,0.7407953762815624,-0.8093982448803362,-0.061384384139230704,0.5074668730496471 3430 Amide binding 23 110 2.755104144030706 0.0058673456231379 P55786,Q15392,P24390,P45880,Q9UIQ6,P21796,P52292,Q9UM22,P42892,Q9Y287,Q9H7Z7,P00374,O43731,Q9Y584,Q03519,Q8WTV0,Q9NQX7,P07602,Q03518,O00264,Q9Y680,P49748,O14773 Functions GO Molecular function msigdb_gomf 128,2,4,13,143,20,156,34,161,166,172,52,59,62,198,71,203,77,86,216,95,232,110 1940,1365,216,2257,1943,1831,3404,2739,110,1123,660,1019,2974,59,2940,3095,3150,52,507,684,443,3405,77,1470,3217,3151,1210,3402,330,2789,20,2538,3347,4,2629,3395,2710,3113,1794,2262,985,2056,2670,842,1573,161,3221,13,2752,471,232,2547,1958,1479,3350,156,3131,2587,128,511,2718,2012,2361,2677,1903,2459,2228,86,198,3377,2266,2554,2556,1967,2512,3133,3099,355,2,1914,828,71,2807,460,366,1002,1816,3407,917,383,744,3365,1664,2143,1666,172,2037,203,658,386,243,1154,1774,143,34,3366,166,1994,62,95 -0.22034471621492466,0.027163091494653614,1.4494309133701686,-0.36090298236806184,-0.22034471621492466,-0.17439114903384173,-2.0313624559825123,-0.6298806123677426,2.360226918485896,0.15704238472925763,0.4675011541744141,0.22071433819033928,-0.7833273588538234,3.104102422844003,-0.7574012545226345,-0.8884981438055674,-0.9689694457036316,3.2607896593204937,0.6448869477951056,0.447397619113444,0.7217588966997998,-2.0313624559825123,2.8157767839559593,-0.01690917370953021,-1.0784930750204527,-0.9689694457036316,0.11413110287400714,-1.8963047213495623,0.9638324211451322,-0.6551091457204445,3.9859536481432736,-0.5057234167351391,-1.3643448569490237,4.687680585731818,-0.5549954789805401,-1.7012045060061012,-0.6047865559806115,-0.9151668939436284,-0.151577544698465,-0.36090298236806184,0.24175657929060165,-0.2667413189986047,-0.5798253703616462,0.32503982365867656,-0.061384384139230704,1.8325459149864132,-1.0784930750204527,4.222429217331235,-0.6298806123677426,0.6834693746272135,1.3995215238872651,-0.5057234167351391,-0.22034471621492466,-0.01690917370953021,-1.3939449866996778,1.8632581140200792,-0.9419899846973533,-0.5302953342350691,2.1755552047661753,0.6448869477951056,-0.6047865559806115,-0.24348703633272678,-0.40868858056019347,-0.5798253703616462,-0.19731314994998111,-0.4569583228314796,-0.3371883420413084,2.672453216244307,1.5640718300941014,-1.5757554991734064,-0.36090298236806184,-0.5057234167351391,-0.5057234167351391,-0.22034471621492466,-0.4812782346091039,-0.9419899846973533,-0.8884981438055674,0.8905672747951905,4.706308247813215,-0.19731314994998111,0.3456433744169804,2.917749605386218,-0.6551091457204445,0.7026504351173741,0.872085387655934,0.24175657929060165,-0.151577544698465,-2.0313624559825123,0.28357365910325655,0.8349190753908383,0.406945511095729,-1.4537345413628453,-0.08377571033449493,-0.2901087935675131,-0.08377571033449493,1.7236380473068795,-0.24348703633272678,1.5315716196659703,0.487523996503178,0.8349190753908383,1.3322253587909487,0.15704238472925763,-0.12887118746947637,2.0290981867058675,3.5618375403217266,-1.4537345413628453,1.8016559746006866,-0.22034471621492466,3.0796079772709244,2.592690371019141 3430 Ion transport 23 49 2.7545875296001645 0.0058766168687638 Q9NUT2,Q93050,P55011,P45880,P21796,P20020,O95202,P06576,Q15043,O75964,Q9UM00,Q9Y277,Q8NE86,Q15904,Q9C0H2,P24539,P56385,Q4KMQ2,P51798,Q9Y6M7,Q9Y487,P16615,Q8NE01 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 398,136,394,13,20,278,154,536,415,33,558,294,425,434,45,183,446,608,335,619,94,249,381 2859,3268,33,154,2293,897,536,2049,249,278,1475,3333,20,1049,183,2214,2001,1094,2546,13,3255,335,2170,394,2588,446,2360,2986,415,434,608,3368,1107,1393,381,425,136,1038,1770,45,2033,398,2491,558,294,94,639,3330,619 -0.7059762210511288,-1.1623836255706177,3.5731076371518076,1.8785482781004688,-0.38473594847995757,0.28357365910325655,0.6060065128039738,-0.2667413189986047,1.2640484788395443,1.1600736506845353,-0.01690917370953021,-1.3349373118137702,3.9859536481432736,0.19958181332532843,1.6444566286616846,-0.3371883420413084,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,4.222429217331235,-1.1342490728645735,0.945614424806558,-0.31359071053648363,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.7833273588538234,0.7786548166059916,0.7407953762815624,0.5273305006198339,-1.4839299067547875,0.17835812614782434,0.027163091494653614,0.8349190753908383,0.7597604826477616,2.1174474931929272,0.22071433819033928,-0.12887118746947637,3.3784536775429674,-0.24348703633272678,0.816233531485841,-0.4569583228314796,0.5864529093583782,1.107291420206707,2.6060641851362782,0.5074668730496471,-1.3057195477388794,0.5273305006198339 3430 Vacuolar membrane 40 123 2.7514737995575653 0.0059327765476695 Q07065,O75165,Q93050,Q9UIQ6,Q8IV08,Q9H2V7,Q96DM3,Q14108,P11279,Q15043,Q8N511,O75955,P42892,O15400,Q15382,Q96RL7,Q14849,Q8NCG7,P42785,Q96GC9,P11117,Q16625,P04062,P13473,O15260,Q8WTV0,Q9NQX7,Q7Z3C6,P07602,P51798,Q9BTU6,Q9Y487,P10253,O15118,O14678,P42345,O00203,P10619,Q9NZJ7,O75503 Localization GO Cellular component msigdb_gocc 256,506,136,143,273,148,546,22,413,415,32,534,161,532,290,292,43,302,47,569,187,322,68,196,319,71,203,459,77,335,480,94,349,98,222,354,483,113,243,116 483,659,222,98,319,532,1465,1887,1621,3266,506,116,534,2104,1676,68,1281,2785,77,3372,2164,1470,2346,3217,349,113,187,2295,413,196,1567,1475,3333,2109,1893,1420,1094,2546,2398,354,47,161,2505,1684,1685,335,1174,1480,1799,706,1346,2360,3317,2677,2401,903,1531,3056,256,2266,2636,2013,2175,22,43,415,290,322,881,459,273,1393,654,32,302,568,2959,71,1446,2604,717,136,1231,3206,1816,546,569,3176,2483,292,2522,633,2693,3319,480,3427,2139,3210,1665,1150,1008,1320,148,3249,203,1875,243,3005,1876,1989,1824,2491,143,1014,2288,1121,3166,784,1828,94,639,698,1778 0.6642150900524303,0.4675011541744141,1.4328472746723286,2.5388692262913795,1.000074973722675,0.6060065128039738,-0.01690917370953021,-0.19731314994998111,-0.08377571033449493,-1.1623836255706177,0.6448869477951056,2.3181620708424706,0.6060065128039738,-0.2901087935675131,-0.10627094673633292,2.993031551841918,0.07084055395748909,-0.6551091457204445,2.8157767839559593,-1.5143297421023834,-0.31359071053648363,-0.01690917370953021,-0.40868858056019347,-1.0784930750204527,0.9089823832894932,2.3322196827838484,1.6124494198193353,-0.38473594847995757,0.7786548166059916,1.5640718300941014,-0.061384384139230704,-0.01690917370953021,-1.3349373118137702,-0.2901087935675131,-0.19731314994998111,0.005176812076117423,0.17835812614782434,-0.5057234167351391,-0.4327622425712757,0.8905672747951905,3.3551136813137883,1.8325459149864132,-0.4812782346091039,-0.10627094673633292,-0.10627094673633292,0.945614424806558,0.13563368348203628,-0.01690917370953021,-0.151577544698465,0.4272126540305929,0.04905067418434559,-0.40868858056019347,-1.2766888241918128,-0.5798253703616462,-0.4327622425712757,0.28357365910325655,-0.03909589167063334,-0.8356157493053581,1.2468635762934643,-0.36090298236806184,-0.5549954789805401,-0.24348703633272678,-0.31359071053648363,3.9859536481432736,3.413286496271575,0.7786548166059916,1.1249455781236504,1.000074973722675,0.3043501904123781,0.7026504351173741,1.1775484830852023,0.027163091494653614,0.487523996503178,3.6735633983186133,1.071800525038966,0.5668228264787173,-0.7574012545226345,2.917749605386218,0.005176812076117423,-0.5302953342350691,0.4272126540305929,2.1174474931929272,0.11413110287400714,-1.0508669815631295,-0.151577544698465,0.6060065128039738,0.5668228264787173,-0.9961073484547495,-0.4569583228314796,1.1249455781236504,-0.4812782346091039,0.5074668730496471,-0.5798253703616462,-1.2766888241918128,0.6834693746272135,-8.4659830013842,-0.2901087935675131,-1.0508669815631295,-0.08377571033449493,0.15704238472925763,0.24175657929060165,0.07084055395748909,1.9392759124745347,-1.1062863390031978,1.5315716196659703,-0.17439114903384173,1.3322253587909487,-0.7833273588538234,-0.17439114903384173,-0.22034471621492466,-0.151577544698465,-0.4569583228314796,2.0290981867058675,0.24175657929060165,-0.36090298236806184,0.17835812614782434,-0.9689694457036316,0.3865954317326442,-0.151577544698465,2.6060641851362782,0.5074668730496471,0.447397619113444,-0.12887118746947637 3430 Intrinsic component of mitochondrial inner membrane 15 30 2.748408292513808 0.0059885384902129 O43819,Q9Y512,Q15070,Q5XKP0,Q8NE86,Q13505,Q9H9B4,Q9Y2R0,Q9BUR5,Q96NB2,Q99595,O14925,Q6P4A7,Q16134,O60830 Localization GO Cellular component msigdb_gocc 533,419,126,357,425,75,530,76,275,352,56,122,247,539,30 122,533,30,758,935,937,3373,1172,1690,75,126,539,666,797,357,247,585,425,352,56,275,3190,530,2327,1321,3037,1878,76,2155,419 2.233047134387105,0.6060065128039738,3.684618516209035,0.3865954317326442,0.2627094020641012,0.2627094020641012,-1.5449371974827035,0.13563368348203628,-0.10627094673633292,2.854234483045071,2.1899853400179143,0.6060065128039738,0.4675011541744141,0.3661616464083245,0.8905672747951905,1.2811766906485145,0.5471155860670778,0.7597604826477616,0.9089823832894932,3.1648792186751504,1.1775484830852023,-1.023405807478901,0.6254843056815558,-0.38473594847995757,0.07084055395748909,-0.8093982448803362,-0.17439114903384173,2.854234483045071,-0.2901087935675131,0.7786548166059916 3430 Golgi cisterna 9 24 2.7321169210320697 0.0062928804507635 O95249,O60512,Q9Y6B6,Q96L58,Q9H4A6,Q15363,Q8NBN3,O00461,Q8TBA6 Localization GO Cellular component msigdb_gocc 258,231,300,234,268,241,212,23,286 23,1202,231,258,684,2049,1376,3025,1430,821,320,1298,1064,241,554,212,286,2132,234,2764,633,268,2039,300 3.9438430597865275,0.11413110287400714,1.3995215238872651,1.2296215579874639,0.447397619113444,-0.2667413189986047,0.027163091494653614,-0.8093982448803362,0.005176812076117423,0.3456433744169804,1.000074973722675,0.07084055395748909,0.19958181332532843,1.3491309609547064,0.5864529093583782,1.482441592729086,1.1425395010761892,-0.2901087935675131,1.3995215238872651,-0.6298806123677426,0.5074668730496471,1.1949644490190432,-0.24348703633272678,1.0895765601315317 3430 Abnormal circulating lipid concentration 24 80 2.7296851416343224 0.0063394840860202 Q15392,P42858,Q9Y4P3,P06280,Q13426,O43772,Q8N511,Q9Y6B6,Q15904,Q9UBM7,Q14739,P23786,O95470,P07602,O75844,O75845,P22830,Q16836,Q15800,P49748,P28340,Q9NZJ7,Q9NVI7,P37268 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,259,269,389,21,152,32,300,434,438,311,63,64,77,81,468,470,356,101,232,240,243,385,123 1087,1996,1243,152,549,758,2780,81,468,935,64,2978,389,938,77,1948,3413,470,63,942,240,3315,2543,841,3129,123,3367,842,1573,259,2672,874,232,600,1574,1479,2951,2302,1959,2912,2507,1482,2872,649,2876,2063,821,1299,21,2233,311,1223,2,1259,101,434,356,2802,1971,2182,32,2959,2071,2369,2188,2030,3176,517,2037,385,243,438,2378,967,697,2341,269,1994,1728,300 0.17835812614782434,-0.24348703633272678,0.09253370913532158,1.8937948621783494,0.5864529093583782,0.3865954317326442,-0.6551091457204445,2.7510864124399865,0.6834693746272135,0.2627094020641012,3.0426662360183325,-0.7833273588538234,0.816233531485841,0.2627094020641012,2.8157767839559593,-0.22034471621492466,-2.242048039872144,0.6834693746272135,3.0673208707632353,0.2627094020641012,1.3491309609547064,-1.2766888241918128,-0.5057234167351391,0.32503982365867656,-0.9419899846973533,2.2187310778900433,-1.4839299067547875,0.32503982365867656,-0.061384384139230704,1.2296215579874639,-0.5798253703616462,0.3043501904123781,1.3995215238872651,0.5273305006198339,-0.061384384139230704,-0.01690917370953021,-0.7574012545226345,-0.38473594847995757,-0.22034471621492466,-0.7316181307528602,-0.4812782346091039,-0.01690917370953021,-0.7059762210511288,0.487523996503178,-0.7059762210511288,-0.2667413189986047,0.3456433744169804,0.07084055395748909,3.9859536481432736,-0.3371883420413084,1.036063009474167,0.11413110287400714,4.706308247813215,0.09253370913532158,2.5117605953310402,0.7407953762815624,0.8905672747951905,-0.6551091457204445,-0.22034471621492466,-0.31359071053648363,3.6735633983186133,-0.7574012545226345,-0.2667413189986047,-0.40868858056019347,-0.31359071053648363,-0.24348703633272678,-0.9961073484547495,0.6448869477951056,-0.24348703633272678,0.8349190753908383,1.3322253587909487,0.7407953762815624,-0.40868858056019347,0.2627094020641012,0.447397619113444,-0.38473594847995757,1.1949644490190432,-0.22034471621492466,-0.10627094673633292,1.0895765601315317 3430 Calcium signaling pathway 7 19 2.719598888321769 0.0065361148231086 P16615,Q9Y277,P45880,P21796,P20020,P12236,P12235 Processes and pathways KEGG Pathways msigdb_kegg 249,294,13,20,278,218,182 488,1335,304,182,218,249,1247,2536,2746,2667,278,20,1049,13,2554,1138,1802,1933,294 0.6642150900524303,0.04905067418434559,1.0539628363107982,1.6444566286616846,1.4494309133701686,1.2640484788395443,0.09253370913532158,-0.5057234167351391,-0.6298806123677426,-0.5798253703616462,1.1600736506845353,3.9859536481432736,0.19958181332532843,4.222429217331235,-0.5057234167351391,0.15704238472925763,-0.151577544698465,-0.19731314994998111,1.107291420206707 3430 Cation transport 54 160 2.7173716214526675 0.0065802677589226 P42858,Q13423,Q9NUT2,Q9HD20,Q9Y619,P55011,Q9H9B4,P30536,P14854,P46934,P17931,P21796,P20020,O43772,O95202,P06576,Q15043,O75964,Q9UM00,Q8NE86,P0DP25,P13073,Q96GC9,P24539,Q96ES6,P20337,P12235,Q6YHU6,P47985,P56385,Q99959,Q00535,Q9P2D1,Q4KMQ2,O75844,O76024,P00403,Q9UDW1,Q96NB2,P30825,Q70HW3,P05067,P78417,Q15907,Q07812,P50570,O43808,Q9UJZ1,O15173,P05141,Q99623,P16615,Q8IYU8,Q7KZN9 Processes and pathways GO Biological process msigdb_gobp 259,130,398,137,266,394,530,12,392,524,523,20,278,152,154,536,415,33,558,425,304,178,569,183,57,562,182,586,191,446,333,582,339,608,81,455,213,92,352,225,97,224,103,111,368,491,486,520,117,488,383,249,250,257 2738,1367,1941,2740,1158,117,1996,152,486,702,2437,623,2387,2860,2160,2900,81,3268,33,455,154,1125,213,732,2707,897,224,488,2665,1335,536,3234,2785,2390,3372,2164,1245,304,1739,2441,3236,182,178,2211,2501,392,249,1247,2536,2746,523,2667,278,562,2296,1475,3333,3219,20,1049,183,1419,2214,1520,2710,3113,12,3076,225,1051,1571,1420,2542,3348,2001,1094,2546,259,2505,524,1374,191,3255,491,1174,1058,2170,394,2588,446,1100,2360,2798,2012,1031,103,1902,1690,582,1531,2228,2229,1252,368,1429,2636,1645,130,1138,1802,2233,1909,415,1064,1699,111,905,608,1107,586,97,257,3383,250,997,425,1352,802,57,569,2997,352,1594,3318,383,2963,333,1502,1006,1150,2144,2850,530,137,924,3428,398,339,92,1933,2491,520,2615,558,2040,1608,1327,2155,266,619 -0.6298806123677426,0.027163091494653614,-0.22034471621492466,-0.6298806123677426,0.13563368348203628,2.2757707336590367,-0.24348703633272678,1.8937948621783494,0.6642150900524303,0.4272126540305929,-0.4569583228314796,0.5074668730496471,-0.4327622425712757,-0.7059762210511288,-0.31359071053648363,-0.7316181307528602,2.7510864124399865,-1.1623836255706177,3.5731076371518076,0.7026504351173741,1.8785482781004688,0.15704238472925763,1.4659622290827485,0.406945511095729,-0.6047865559806115,0.28357365910325655,1.4328472746723286,0.6642150900524303,-0.5798253703616462,0.04905067418434559,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-0.4327622425712757,-1.5143297421023834,-0.31359071053648363,0.09253370913532158,1.0539628363107982,-0.12887118746947637,-0.4569583228314796,-1.1062863390031978,1.6444566286616846,1.6603878760836814,-0.3371883420413084,-0.4812782346091039,0.816233531485841,1.2640484788395443,0.09253370913532158,-0.5057234167351391,-0.6298806123677426,0.6254843056815558,-0.5798253703616462,1.1600736506845353,0.5668228264787173,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,-1.0784930750204527,3.9859536481432736,0.19958181332532843,1.6444566286616846,0.005176812076117423,-0.3371883420413084,-0.03909589167063334,-0.6047865559806115,-0.9151668939436284,4.222429217331235,-0.8619817453617755,1.4328472746723286,0.19958181332532843,-0.061384384139230704,0.005176812076117423,-0.5057234167351391,-1.3643448569490237,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,1.2296215579874639,-0.4812782346091039,0.6254843056815558,0.027163091494653614,1.5963727964305452,-1.1342490728645735,0.6642150900524303,0.13563368348203628,0.19958181332532843,-0.31359071053648363,0.816233531485841,-0.5302953342350691,0.7217588966997998,0.17835812614782434,-0.40868858056019347,-0.6551091457204445,-0.24348703633272678,0.22071433819033928,2.4708459283490147,-0.19731314994998111,-0.10627094673633292,0.5471155860670778,-0.03909589167063334,-0.3371883420413084,-0.3371883420413084,0.09253370913532158,0.8535361731217637,0.005176812076117423,-0.5549954789805401,-0.08377571033449493,2.1610865858455655,0.15704238472925763,-0.151577544698465,-0.3371883420413084,-0.19731314994998111,0.7786548166059916,0.19958181332532843,-0.10627094673633292,2.34624122931555,0.28357365910325655,0.5273305006198339,0.17835812614782434,0.5471155860670778,2.552373754198136,1.2468635762934643,-1.6067879521771078,1.2640484788395443,0.24175657929060165,0.7597604826477616,0.04905067418434559,0.3661616464083245,3.1527758461637907,0.5668228264787173,-0.7833273588538234,0.9089823832894932,-0.061384384139230704,-1.2766888241918128,0.8349190753908383,-0.7574012545226345,0.9638324211451322,-0.01690917370953021,0.24175657929060165,0.15704238472925763,-0.2901087935675131,-0.6804737926663148,0.6254843056815558,2.1028225946561765,0.28357365910325655,-10.923149187726121,0.816233531485841,0.945614424806558,2.6194057651180533,-0.19731314994998111,-0.4569583228314796,0.6448869477951056,-0.5302953342350691,0.5864529093583782,-0.24348703633272678,-0.061384384139230704,0.07084055395748909,-0.2901087935675131,1.2123219939175685,0.5273305006198339 3430 Secondary active transmembrane transporter activity 11 19 2.7149493725592317 0.0066285902915623 P53985,P12236,Q8NE86,P12235,P55011,Q9UBX3,P51798,P05141,Q96ES6,O95202,Q15043 Functions GO Molecular function msigdb_gomf 509,218,425,182,394,50,335,488,57,154,415 154,488,2164,182,218,335,1290,509,394,1690,739,415,1699,425,57,1006,2850,50,619 1.8785482781004688,0.6642150900524303,-0.31359071053648363,1.6444566286616846,1.4494309133701686,0.945614424806558,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.10627094673633292,0.406945511095729,0.7786548166059916,-0.10627094673633292,0.7597604826477616,3.1527758461637907,0.24175657929060165,-0.6804737926663148,3.2845170686821423,0.5273305006198339 3430 Cytochrome complex 7 18 2.714750105146193 0.0066325797353212 P14406,P22695,P13073,O14949,P00403,Q9UDW1,P47985 Localization GO Cellular component msigdb_gocc 9,106,178,82,213,92,191 1941,82,213,1245,2666,1739,178,9,392,3127,3128,2296,106,1051,191,257,92,1609 -0.22034471621492466,2.7380578010529537,1.4659622290827485,0.09253370913532158,-0.5798253703616462,-0.12887118746947637,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,-0.38473594847995757,2.4019708945127647,0.19958181332532843,1.5963727964305452,1.2468635762934643,2.6194057651180533,-0.061384384139230704 3430 ER-Golgi transport 9 51 2.7088631248875834 0.006751418626419 O95249,P24390,Q9Y6B6,O95197,Q9P2W9,Q15363,Q9Y282,Q9NR31,O43731 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 258,4,300,42,107,241,85,248,59 1275,2158,727,3070,59,1784,785,2103,2781,42,258,1208,561,469,4,1341,1250,874,315,1376,2114,1029,2673,2796,706,1641,664,1575,1255,241,990,1703,653,957,995,853,2241,2132,2369,2029,2693,695,1820,248,107,1360,85,1827,1199,811,300 0.07084055395748909,-0.31359071053648363,0.406945511095729,-0.8619817453617755,3.104102422844003,-0.151577544698465,0.3661616464083245,-0.2901087935675131,-0.6551091457204445,3.4479092742401036,1.2296215579874639,0.11413110287400714,0.5668228264787173,0.6834693746272135,4.687680585731818,0.04905067418434559,0.09253370913532158,0.3043501904123781,1.0181005541038732,0.027163091494653614,-0.2901087935675131,0.22071433819033928,-0.5798253703616462,-0.6551091457204445,0.4272126540305929,-0.08377571033449493,0.4675011541744141,-0.061384384139230704,0.09253370913532158,1.3491309609547064,0.24175657929060165,-0.10627094673633292,0.487523996503178,0.2627094020641012,0.24175657929060165,0.32503982365867656,-0.3371883420413084,-0.2901087935675131,-0.40868858056019347,-0.24348703633272678,-0.5798253703616462,0.447397619113444,-0.151577544698465,1.2811766906485145,2.4019708945127647,0.04905067418434559,2.685636217276718,-0.151577544698465,0.13563368348203628,0.3661616464083245,1.0895765601315317 3430 Transport vesicle 37 91 2.706517535202956 0.0067992991468939 O95249,Q9Y3B3,P24390,Q13277,P01889,Q92572,Q9BT78,P20020,O00461,Q9Y678,Q8TBA6,P11279,P62820,O75396,O15400,Q9BVK6,Q9Y6B6,Q13190,P0DP25,P50897,P04439,O43731,Q86Y82,P20337,O95487,Q92542,P49755,P61020,O15260,O76024,P05067,O15498,Q99523,Q15907,Q15363,Q9NR31,O75592 Localization GO Cellular component msigdb_gocc 258,133,4,260,507,801,672,278,23,811,286,413,664,785,532,427,300,301,304,53,684,59,714,562,561,717,315,447,319,455,224,727,633,111,241,248,624 1367,23,1275,2740,2158,319,532,727,59,1465,1468,2099,1784,1674,785,624,455,2103,2781,258,2498,1208,561,1676,507,684,224,3217,3151,304,1210,413,2210,278,562,1567,4,1520,3017,1341,2546,1250,874,315,53,1685,3153,1174,2114,1029,2673,2871,447,789,1346,2360,1641,664,1531,301,260,1179,2512,2175,2880,954,1434,1064,241,990,111,714,286,717,801,1815,1764,633,672,427,1268,248,2089,1360,3412,1933,1827,133,811,300,1328 0.027163091494653614,3.9438430597865275,0.07084055395748909,-0.6298806123677426,-0.31359071053648363,1.000074973722675,0.6060065128039738,0.406945511095729,3.104102422844003,-0.01690917370953021,-0.01690917370953021,-0.2901087935675131,-0.151577544698465,-0.10627094673633292,0.3661616464083245,0.5074668730496471,0.7026504351173741,-0.2901087935675131,-0.6551091457204445,1.2296215579874639,-0.4812782346091039,0.11413110287400714,0.5668228264787173,-0.10627094673633292,0.6448869477951056,0.447397619113444,1.4328472746723286,-1.0784930750204527,-0.9689694457036316,1.0539628363107982,0.11413110287400714,0.7786548166059916,-0.3371883420413084,1.1600736506845353,0.5668228264787173,-0.061384384139230704,4.687680585731818,-0.03909589167063334,-0.8093982448803362,0.04905067418434559,-0.5057234167351391,0.09253370913532158,0.3043501904123781,1.0181005541038732,3.2250123758744826,-0.10627094673633292,-0.9689694457036316,0.13563368348203628,-0.2901087935675131,0.22071433819033928,-0.5798253703616462,-0.7059762210511288,0.7217588966997998,0.3661616464083245,0.04905067418434559,-0.40868858056019347,-0.08377571033449493,0.4675011541744141,-0.03909589167063334,1.071800525038966,1.2296215579874639,0.13563368348203628,-0.4812782346091039,-0.31359071053648363,-0.7059762210511288,0.2627094020641012,0.005176812076117423,0.19958181332532843,1.3491309609547064,0.24175657929060165,2.34624122931555,0.4272126540305929,1.1425395010761892,0.4272126540305929,0.3661616464083245,-0.151577544698465,-0.12887118746947637,0.5074668730496471,0.4675011541744141,0.7597604826477616,0.09253370913532158,1.2811766906485145,-0.2667413189986047,0.04905067418434559,-2.2062494461722344,-0.19731314994998111,-0.151577544698465,2.1610865858455655,0.3661616464083245,1.0895765601315317,0.07084055395748909 3430 Sphingolipid metabolism 8 12 2.7028638931498765 0.0068744889783787 Q13510,P15289,O95470,P04062,P16278,P06280,Q06136,O43681 Processes and pathways KEGG Pathways msigdb_kegg 158,374,64,68,38,389,87,428 441,1673,428,64,68,389,374,38,87,158,2522,1041 0.7217588966997998,-0.10627094673633292,0.7407953762815624,3.0426662360183325,2.993031551841918,0.816233531485841,0.8349190753908383,3.5165359909007803,2.672453216244307,1.8479240879335823,-0.4812782346091039,0.22071433819033928 3430 Corneal opacity 17 59 2.70078461253236 0.0069176121247405 Q13510,Q16625,P04062,P16278,Q9Y4P3,P06280,Q9UBM7,P51648,O75844,P10619,Q9H9S5,O43505,Q06136,Q8NAT1,Q9NVI7,O95202,O75845 Drugs and Diseases Human Phenotype Ontology msigdb_hp 158,322,68,38,269,389,438,79,81,113,411,246,87,544,385,154,468 1560,1087,1330,2097,246,1047,2205,1243,1735,2942,549,593,81,468,1207,154,2345,2978,68,2582,389,1415,1162,113,38,787,1474,3315,2543,842,2112,1479,79,875,686,1423,2872,649,1963,87,2364,2637,158,1223,1224,2019,322,1182,2181,544,2320,2522,411,385,1602,438,2378,2253,269 -0.061384384139230704,0.17835812614782434,0.04905067418434559,-0.2901087935675131,1.2811766906485145,0.19958181332532843,-0.3371883420413084,0.09253370913532158,-0.12887118746947637,-0.7574012545226345,0.5864529093583782,0.5273305006198339,2.7510864124399865,0.6834693746272135,0.11413110287400714,1.8785482781004688,-0.40868858056019347,-0.7833273588538234,2.993031551841918,-0.5302953342350691,0.816233531485841,0.005176812076117423,0.13563368348203628,2.3322196827838484,3.5165359909007803,0.3661616464083245,-0.01690917370953021,-1.2766888241918128,-0.5057234167351391,0.32503982365867656,-0.2901087935675131,-0.01690917370953021,2.777052623692763,0.3043501904123781,0.447397619113444,0.005176812076117423,-0.7059762210511288,0.487523996503178,-0.22034471621492466,2.672453216244307,-0.40868858056019347,-0.5549954789805401,1.8479240879335823,0.11413110287400714,0.11413110287400714,-0.24348703633272678,1.000074973722675,0.13563368348203628,-0.31359071053648363,0.6060065128039738,-0.38473594847995757,-0.4812782346091039,0.7974789711276091,0.8349190753908383,-0.061384384139230704,0.7407953762815624,-0.40868858056019347,-0.3371883420413084,1.1949644490190432 3430 Chemical homeostasis 54 187 2.6996529129219144 0.0069411849402176 P54646,P30519,P42858,P53985,Q93050,Q9HD20,P55011,Q9P035,P30536,Q9Y5X3,P09601,P20020,O95202,Q5BJF2,Q8N511,P06576,O43819,Q15043,Q9UM00,Q9Y6C9,Q9Y6B6,P09874,Q8NE86,Q15904,P42785,P0DP25,P50897,Q8NF37,Q9BWH2,Q96A33,P09429,P04062,O15260,Q8WTV0,Q9P2D1,O76024,Q8N5M9,Q9H1E3,Q9Y487,P05067,O15118,Q15067,P78417,P52789,O00203,Q15907,Q07812,P28340,Q9UJZ1,O75503,P16615,Q8IYU8,Q8NE01,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 254,1,259,509,136,137,394,531,12,270,17,278,154,31,32,536,533,415,558,167,300,552,425,434,47,304,53,568,454,323,444,68,319,71,339,455,210,211,94,224,98,350,103,236,483,111,368,240,520,116,249,250,381,127 2043,483,1366,1615,1944,2739,659,98,680,319,533,2437,1205,623,116,935,3321,455,3400,154,1889,2498,1208,937,2664,732,840,68,3371,2707,897,224,1335,536,938,1022,3234,3011,3372,1469,444,17,552,2049,304,2443,2211,3182,2788,249,1247,1213,1743,2536,1793,2746,2667,2393,278,940,1248,1049,2445,1520,3395,2710,240,1476,1954,1,12,3076,3315,985,2546,2111,1343,1681,47,259,1682,2006,53,1685,2057,1376,3154,236,509,254,2170,394,3237,2360,1482,1031,764,2550,2635,103,582,1294,1296,2119,368,3396,1645,3411,2512,1802,2233,3240,1649,1909,415,350,652,1698,1064,434,111,1651,2267,666,31,881,1107,586,2024,1393,3383,250,911,997,32,210,381,425,568,71,1352,629,136,323,1231,2371,2997,3176,1594,856,2135,1817,3318,2963,1927,454,1006,3369,211,2143,1982,2144,1505,1600,137,924,2086,127,3428,2335,2614,531,339,2339,1933,2491,520,2699,558,2041,94,2155,270,3330,300,167,619 -0.2667413189986047,0.6642150900524303,0.027163091494653614,-0.08377571033449493,-0.22034471621492466,-0.6298806123677426,0.4675011541744141,2.5388692262913795,0.447397619113444,1.000074973722675,0.6060065128039738,-0.4569583228314796,0.11413110287400714,0.5074668730496471,2.3181620708424706,0.2627094020641012,-1.3057195477388794,0.7026504351173741,-1.8631817950549134,1.8785482781004688,-0.19731314994998111,-0.4812782346091039,0.11413110287400714,0.2627094020641012,-0.5798253703616462,0.406945511095729,0.32503982365867656,2.993031551841918,-1.5143297421023834,-0.6047865559806115,0.28357365910325655,1.4328472746723286,0.04905067418434559,0.6060065128039738,0.2627094020641012,0.22071433819033928,-1.1062863390031978,-0.8093982448803362,-1.5143297421023834,-0.01690917370953021,0.7217588966997998,4.05893051652828,0.5864529093583782,-0.2667413189986047,1.0539628363107982,-0.4569583228314796,-0.3371883420413084,-1.023405807478901,-0.6551091457204445,1.2640484788395443,0.09253370913532158,0.11413110287400714,-0.12887118746947637,-0.5057234167351391,-0.151577544698465,-0.6298806123677426,-0.5798253703616462,-0.4327622425712757,1.1600736506845353,0.2627094020641012,0.09253370913532158,0.19958181332532843,-0.4569583228314796,-0.03909589167063334,-1.7012045060061012,-0.6047865559806115,1.3491309609547064,-0.01690917370953021,-0.22034471621492466,5.005721299000376,4.222429217331235,-0.8619817453617755,-1.2766888241918128,0.24175657929060165,-0.5057234167351391,-0.2901087935675131,0.04905067418434559,-0.10627094673633292,3.3551136813137883,1.2296215579874639,-0.10627094673633292,-0.24348703633272678,3.2250123758744826,-0.10627094673633292,-0.2667413189986047,0.027163091494653614,-0.9689694457036316,1.382778649014379,0.6448869477951056,1.2468635762934643,-0.31359071053648363,0.816233531485841,-1.1062863390031978,-0.40868858056019347,-0.01690917370953021,0.22071433819033928,0.3865954317326442,-0.5057234167351391,-0.5549954789805401,2.4708459283490147,0.5471155860670778,0.07084055395748909,0.07084055395748909,-0.2901087935675131,0.8535361731217637,-1.7012045060061012,-0.08377571033449493,-2.2062494461722344,-0.4812782346091039,-0.151577544698465,-0.3371883420413084,-1.1062863390031978,-0.08377571033449493,-0.19731314994998111,0.7786548166059916,0.9089823832894932,0.487523996503178,-0.10627094673633292,0.19958181332532843,0.7407953762815624,2.34624122931555,-0.08377571033449493,-0.36090298236806184,0.4675011541744141,3.6735633983186133,0.3043501904123781,0.17835812614782434,0.5471155860670778,-0.24348703633272678,0.027163091494653614,-1.6067879521771078,1.2640484788395443,0.28357365910325655,0.24175657929060165,3.6735633983186133,1.4988693711510455,0.8349190753908383,0.7597604826477616,0.5668228264787173,2.917749605386218,0.04905067418434559,0.5074668730496471,2.1174474931929272,1.000074973722675,0.11413110287400714,-0.40868858056019347,-0.7833273588538234,-0.9961073484547495,-0.061384384139230704,0.32503982365867656,-0.2901087935675131,-0.151577544698465,-1.2766888241918128,-0.7574012545226345,-0.19731314994998111,0.7217588966997998,0.24175657929060165,-1.4839299067547875,1.4988693711510455,-0.2901087935675131,-0.22034471621492466,-0.2901087935675131,-0.01690917370953021,-0.061384384139230704,2.1028225946561765,0.28357365910325655,-0.2667413189986047,2.1899853400179143,-10.923149187726121,-0.38473594847995757,-0.5302953342350691,0.6254843056815558,0.945614424806558,-0.38473594847995757,-0.19731314994998111,-0.4569583228314796,0.6448869477951056,-0.5798253703616462,0.5864529093583782,-0.24348703633272678,2.6060641851362782,-0.2901087935675131,1.1949644490190432,-1.3057195477388794,1.0895765601315317,1.8016559746006866,0.5273305006198339 3430 Carboxylic acid transport 12 32 2.6956135448779976 0.0070259127541989 P53985,Q15041,O60831,P55011,Q9Y619,P07602,Q9UBX3,Q9NZJ7,Q9BQT8,Q9H2D1,Q96NB2,P30825 Processes and pathways GO Biological process msigdb_gobp 509,424,505,394,266,77,50,243,409,120,352,225 505,1369,817,937,1890,2665,77,2164,1518,1418,1286,225,1290,509,394,1902,739,424,710,1699,3187,1393,352,409,120,2850,530,2086,243,50,967,266 0.6448869477951056,0.027163091494653614,0.3456433744169804,0.2627094020641012,-0.19731314994998111,-0.5798253703616462,2.8157767839559593,-0.31359071053648363,-0.03909589167063334,0.005176812076117423,0.07084055395748909,1.4328472746723286,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.19731314994998111,0.406945511095729,0.7597604826477616,0.4272126540305929,-0.10627094673633292,-1.023405807478901,0.027163091494653614,0.9089823832894932,0.7974789711276091,2.2615667415404976,-0.6804737926663148,0.6254843056815558,-0.2667413189986047,1.3322253587909487,3.2845170686821423,0.2627094020641012,1.2123219939175685 3430 Clumsiness 10 21 2.6934578243585525 0.0070715091592206 Q13510,P15289,Q15067,P42858,Q9NR77,P07602,O14773,Q9NZJ7,O75503,O43681 Drugs and Diseases Human Phenotype Ontology msigdb_hp 158,374,350,259,297,77,110,243,116,428 1560,110,1087,428,533,116,2745,77,374,2866,871,259,1296,158,350,1759,1535,856,297,243,927 -0.061384384139230704,2.360226918485896,0.17835812614782434,0.7407953762815624,0.6060065128039738,2.3181620708424706,-0.6298806123677426,2.8157767839559593,0.8349190753908383,-0.7059762210511288,0.3043501904123781,1.2296215579874639,0.07084055395748909,1.8479240879335823,0.9089823832894932,-0.12887118746947637,-0.03909589167063334,0.32503982365867656,1.0895765601315317,1.3322253587909487,0.28357365910325655 3430 Inorganic ion transmembrane transport 41 115 2.6930625114287907 0.0070798993327285 P42858,Q13423,Q9NUT2,Q9HD20,P55011,P14854,P46934,P21796,P20020,O95202,P06576,Q15043,O75964,Q9UM00,Q8NE86,P0DP25,Q9UBX3,P13073,Q96GC9,P24539,Q96ES6,P12235,Q6YHU6,P47985,P56385,Q00535,Q9P2D1,Q4KMQ2,P51798,P00403,Q9UDW1,Q9UHG3,P78417,Q07812,P50570,Q9UJZ1,P05141,Q99623,P16615,Q8IYU8,Q7KZN9 Processes and pathways GO Biological process msigdb_gobp 259,130,398,137,394,392,524,20,278,154,536,415,33,558,425,304,50,178,569,183,57,182,586,191,446,582,339,608,335,213,92,100,103,368,491,520,488,383,249,250,257 2738,1941,1996,2437,623,2387,2860,2900,3268,33,154,213,897,488,2665,536,3234,2785,3372,2164,1245,304,1739,3236,182,178,392,249,1247,2536,2746,2667,278,2296,1475,3333,3219,20,1049,183,2214,1520,2710,3113,3076,1051,3348,2001,1094,2546,259,524,1374,191,3255,491,335,1058,2170,394,2588,446,2360,2012,1031,103,1690,582,739,2229,1252,368,2636,1645,130,1802,2233,1909,415,608,1107,586,257,1393,3383,250,997,425,1352,802,57,569,2997,1594,3318,383,1502,1006,1150,2144,2850,137,924,398,339,50,92,1933,100,2491,520,558,1327,2155,619 -0.6298806123677426,-0.22034471621492466,-0.24348703633272678,-0.4569583228314796,0.5074668730496471,-0.4327622425712757,-0.7059762210511288,-0.7316181307528602,-1.1623836255706177,3.5731076371518076,1.8785482781004688,1.4659622290827485,0.28357365910325655,0.6642150900524303,-0.5798253703616462,0.6060065128039738,-1.1062863390031978,-0.6551091457204445,-1.5143297421023834,-0.31359071053648363,0.09253370913532158,1.0539628363107982,-0.12887118746947637,-1.1062863390031978,1.6444566286616846,1.6603878760836814,0.816233531485841,1.2640484788395443,0.09253370913532158,-0.5057234167351391,-0.6298806123677426,-0.5798253703616462,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,-1.0784930750204527,3.9859536481432736,0.19958181332532843,1.6444566286616846,-0.3371883420413084,-0.03909589167063334,-0.6047865559806115,-0.9151668939436284,-0.8619817453617755,0.19958181332532843,-1.3643448569490237,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,1.2296215579874639,0.6254843056815558,0.027163091494653614,1.5963727964305452,-1.1342490728645735,0.6642150900524303,0.945614424806558,0.19958181332532843,-0.31359071053648363,0.816233531485841,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-0.24348703633272678,0.22071433819033928,2.4708459283490147,-0.10627094673633292,0.5471155860670778,0.406945511095729,-0.3371883420413084,0.09253370913532158,0.8535361731217637,-0.5549954789805401,-0.08377571033449493,2.1610865858455655,-0.151577544698465,-0.3371883420413084,-0.19731314994998111,0.7786548166059916,0.5273305006198339,0.17835812614782434,0.5471155860670778,1.2468635762934643,0.027163091494653614,-1.6067879521771078,1.2640484788395443,0.24175657929060165,0.7597604826477616,0.04905067418434559,0.3661616464083245,3.1527758461637907,0.5668228264787173,-0.7833273588538234,-0.061384384139230704,-1.2766888241918128,0.8349190753908383,-0.01690917370953021,0.24175657929060165,0.15704238472925763,-0.2901087935675131,-0.6804737926663148,2.1028225946561765,0.28357365910325655,0.816233531485841,0.945614424806558,3.2845170686821423,2.6194057651180533,-0.19731314994998111,2.5388692262913795,-0.4569583228314796,0.6448869477951056,0.5864529093583782,0.07084055395748909,-0.2901087935675131,0.5273305006198339 3430 Mitochondria 77 426 2.689699208544578 0.0071516448154962 Q9NS69,Q16740,Q69YU5,P45880,Q8N4H5,O60830,O75964,Q9UBX3,P00374,Q99595,P23786,Q9BXK5,Q13505,Q9Y2R0,Q9NUJ1,Q8WY22,O14949,Q96A26,Q70HW3,Q9UDX5,P22695,Q3SXM5,Q9H2D1,O14925,Q15070,Q13423,Q8NAN2,O95302,Q9P0J0,O43772,O95202,P57105,Q9Y6C9,Q9H4I3,Q9H7Z7,Q7LGA3,O43292,P13073,Q96EX1,P24539,P12235,Q86Y39,P47985,Q9NWS8,Q7Z7H8,Q9Y5L4,P12236,Q9NZ45,Q9NX40,P49748,Q9NUQ2,P52789,Q6P4A7,Q8IYU8,Q7KZN9,Q96CU9,Q9BUR5,Q9H2U1,Q6DKK2,Q7Z4V5,P21912,Q9Y277,Q96NB2,Q8TB36,Q15388,Q16836,Q5XKP0,Q96AY3,Q9NPL8,Q99797,Q8TAE8,Q99623,Q9NVI7,Q9P032,Q9NUT2,Q9NQ29,Q96IX5 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 3,7,11,13,29,30,33,50,52,56,63,73,75,76,78,80,82,88,97,102,106,108,120,122,126,130,142,147,149,152,154,162,167,171,172,175,177,178,186,183,182,188,191,194,201,204,218,227,226,232,235,236,247,250,257,263,275,276,280,285,282,294,352,351,355,356,357,366,372,384,382,383,385,399,398,397,396 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3430 Hydrolase activity hydrolyzing o glycosyl compounds 8 23 2.6877848847030688 0.0071927717174355 O60502,P04062,P16278,P17900,Q9BTY2,Q9NUJ1,P54802,P10253 Functions GO Molecular function msigdb_gomf 223,68,38,104,361,78,124,349 1560,621,223,68,2582,389,1336,3011,1415,349,38,104,841,124,951,1487,1907,554,2413,2522,361,78,2380 -0.061384384139230704,0.5074668730496471,1.4328472746723286,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,-0.8093982448803362,0.005176812076117423,0.9089823832894932,3.5165359909007803,2.4571398271524862,0.32503982365867656,2.2187310778900433,0.2627094020641012,-0.01690917370953021,-0.19731314994998111,0.5864529093583782,-0.4327622425712757,-0.4812782346091039,0.8905672747951905,2.789990541137051,-0.40868858056019347 3430 Organic acid transport 16 46 2.670631272787708 0.0075708761612967 O14678,P53985,Q15041,O60831,P55011,Q9Y619,Q9H2D1,Q9UBX3,O43808,Q9BQT8,P08183,O43772,Q6P4A7,Q96NB2,P30825,P23786 Processes and pathways GO Biological process msigdb_gobp 222,509,424,505,394,266,120,50,486,409,429,152,247,352,225,63 222,678,152,486,505,1369,817,937,1788,3008,1890,2665,1414,429,2164,595,1518,1418,63,1286,2824,225,1842,1574,1290,509,394,1902,1294,739,424,710,1699,3187,247,1393,352,409,120,2850,530,2086,50,967,3191,266 1.4328472746723286,0.447397619113444,1.8937948621783494,0.6642150900524303,0.6448869477951056,0.027163091494653614,0.3456433744169804,0.2627094020641012,-0.151577544698465,-0.8093982448803362,-0.19731314994998111,-0.5798253703616462,0.005176812076117423,0.7407953762815624,-0.31359071053648363,0.5273305006198339,-0.03909589167063334,0.005176812076117423,3.0673208707632353,0.07084055395748909,-0.6804737926663148,1.4328472746723286,-0.17439114903384173,-0.061384384139230704,0.07084055395748909,0.6448869477951056,0.816233531485841,-0.19731314994998111,0.07084055395748909,0.406945511095729,0.7597604826477616,0.4272126540305929,-0.10627094673633292,-1.023405807478901,1.2811766906485145,0.027163091494653614,0.9089823832894932,0.7974789711276091,2.2615667415404976,-0.6804737926663148,0.6254843056815558,-0.2667413189986047,3.2845170686821423,0.2627094020641012,-1.023405807478901,1.2123219939175685 3430 Establishment of protein localization to mitochondrial membrane 10 19 2.660471440314094 0.0078031344625715 Q9Y512,Q9NS69,Q9Y5J9,O14737,Q9Y5L4,P0DP25,Q07812,Q9P0J0,Q15070,Q9Y584 Processes and pathways GO Biological process msigdb_gobp 419,3,420,329,204,304,368,149,126,62 483,329,3150,1161,304,2215,2867,368,126,797,1352,3,149,1609,419,62,2618,420,204 0.6642150900524303,0.9638324211451322,-0.9689694457036316,0.13563368348203628,1.0539628363107982,-0.3371883420413084,-0.7059762210511288,0.8535361731217637,2.1899853400179143,0.3661616464083245,0.04905067418434559,4.706308247813215,1.9392759124745347,-0.061384384139230704,0.7786548166059916,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Calcium-binding protein 8 21 2.660348205173431 0.0078059904358318 P80303,P41208,Q02818,Q14257,P0DP25,Q8IYU8,P43307,Q9BRK5 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 0,65,36,233,304,250,28,160 729,304,3395,2110,65,28,1686,3183,0,36,233,2681,3203,2183,250,1976,2275,317,1401,160,1327 0.406945511095729,1.0539628363107982,-1.7012045060061012,-0.2901087935675131,3.0302984430490625,3.706665868419647,-0.10627094673633292,-1.023405807478901,5.333361777399175,3.527894748469767,1.3995215238872651,-0.5798253703616462,-1.0508669815631295,-0.31359071053648363,1.2640484788395443,-0.22034471621492466,-0.36090298236806184,1.0181005541038732,0.027163091494653614,1.8479240879335823,0.07084055395748909 3430 Lipid biosynthetic process 58 154 2.644785720153446 0.0081742663053996 Q6IAN0,P54646,Q15392,Q8NBX0,Q01968,O94788,Q9P035,P30536,Q14534,Q16850,O95864,Q9NWU1,Q13510,O76062,Q9NPH0,P52429,Q14849,Q9H7Z7,O15228,Q8NCG7,Q9UBM7,O43292,Q8NF37,P48449,Q86YN1,P16435,Q14739,P48651,Q96G23,Q96N66,Q92643,O95470,Q9BXW6,P04062,O15269,Q8WTV0,Q53GQ0,Q13315,O00116,Q8WVX9,Q5T2R2,Q8NCC3,Q9BTU6,Q06136,O75845,P49327,P42345,Q15800,P11802,O60512,P49748,Q9NUQ2,Q8TBX8,P27544,O00767,P37268,O75592,P54619 Processes and pathways GO Biological process msigdb_gobp 514,254,2,135,649,640,531,12,272,146,388,675,158,164,40,553,43,172,421,302,438,177,568,184,185,310,311,431,61,451,588,64,324,68,441,71,202,332,205,613,610,84,480,87,468,471,354,101,596,231,232,235,112,239,484,123,624,625 205,1940,814,1615,3404,484,2434,678,421,441,1673,3069,177,231,1782,1998,1785,624,468,1332,164,640,2977,64,1788,3322,388,1738,1677,68,1890,897,3011,3236,596,1518,1128,2788,3420,310,1247,3280,1248,2538,2790,3314,239,2710,1286,12,1842,985,123,1288,354,2299,3019,184,431,471,232,553,1637,3418,625,254,2830,2632,1294,3156,649,2460,87,1298,3411,332,158,2175,3132,708,768,272,311,43,2725,711,2,1968,1911,1259,101,2267,146,1700,202,797,610,3339,514,773,2126,185,998,135,84,302,568,112,71,613,1863,588,2188,1074,2371,61,451,2193,2521,3244,1315,1452,2849,1316,480,3427,3399,3403,2696,324,3209,922,2034,1666,834,172,2086,40,1236,2331,890,235,675,1041,676,531,1876,438,1878,1933,1605,1119,3277,1042 1.5152459271739311,-0.22034471621492466,0.3456433744169804,-0.08377571033449493,-2.0313624559825123,0.6642150900524303,-0.4569583228314796,0.447397619113444,0.7597604826477616,0.7217588966997998,-0.10627094673633292,-0.8619817453617755,1.6603878760836814,1.3995215238872651,-0.151577544698465,-0.24348703633272678,-0.151577544698465,0.5074668730496471,0.6834693746272135,0.04905067418434559,1.8171233074337798,0.487523996503178,-0.7833273588538234,3.0426662360183325,-0.151577544698465,-1.3057195477388794,0.816233531485841,-0.12887118746947637,-0.10627094673633292,2.993031551841918,-0.19731314994998111,0.28357365910325655,-0.8093982448803362,-1.1062863390031978,0.5273305006198339,-0.03909589167063334,0.15704238472925763,-0.6551091457204445,-2.7320450484961065,1.036063009474167,0.09253370913532158,-1.1906923971648218,0.09253370913532158,-0.5057234167351391,-0.6551091457204445,-1.2766888241918128,1.3491309609547064,-0.6047865559806115,0.07084055395748909,4.222429217331235,-0.17439114903384173,0.24175657929060165,2.2187310778900433,0.07084055395748909,0.8905672747951905,-0.38473594847995757,-0.8093982448803362,1.6444566286616846,0.7407953762815624,0.6834693746272135,1.3995215238872651,0.5864529093583782,-0.08377571033449493,-2.614938713691235,0.5074668730496471,1.2468635762934643,-0.6804737926663148,-0.5549954789805401,0.07084055395748909,-0.9689694457036316,0.487523996503178,-0.4569583228314796,2.672453216244307,0.07084055395748909,-2.2062494461722344,0.9638324211451322,1.8479240879335823,-0.31359071053648363,-0.9419899846973533,0.4272126540305929,0.3865954317326442,1.1775484830852023,1.036063009474167,3.413286496271575,-0.6047865559806115,0.4272126540305929,4.706308247813215,-0.22034471621492466,-0.19731314994998111,0.09253370913532158,2.5117605953310402,-0.36090298236806184,2.0142315842992913,-0.10627094673633292,1.5315716196659703,0.3661616464083245,0.5273305006198339,-1.3349373118137702,0.6448869477951056,0.3865954317326442,-0.2901087935675131,1.6444566286616846,0.24175657929060165,2.1320329656479697,2.6987880108067723,1.071800525038966,0.5668228264787173,2.34624122931555,2.917749605386218,0.5273305006198339,-0.17439114903384173,0.5471155860670778,-0.31359071053648363,0.19958181332532843,-0.40868858056019347,3.104102422844003,0.7217588966997998,-0.31359071053648363,-0.4812782346091039,-1.1062863390031978,0.07084055395748909,0.005176812076117423,-0.6804737926663148,0.07084055395748909,0.6834693746272135,-8.4659830013842,-1.7976755345030844,-1.9633114577538548,-0.5798253703616462,1.000074973722675,-1.0508669815631295,0.28357365910325655,-0.24348703633272678,-0.08377571033449493,0.3456433744169804,1.7236380473068795,-0.2667413189986047,3.482324846985818,0.11413110287400714,-0.38473594847995757,0.3043501904123781,1.3995215238872651,0.4675011541744141,0.22071433819033928,0.4675011541744141,0.6254843056815558,-0.17439114903384173,0.7407953762815624,-0.17439114903384173,-0.19731314994998111,-0.061384384139230704,0.17835812614782434,-1.1623836255706177,0.22071433819033928 3430 Carbohydrate derivative transport 8 13 2.642845444211437 0.0082212553579779 Q8WTV0,Q8TB61,P07602,O43808,Q9NZJ7,P05141,P12236,P12235 Processes and pathways GO Biological process msigdb_gobp 71,39,77,486,243,488,218,182 504,486,488,77,182,218,1482,1182,1393,39,71,2963,243 0.6448869477951056,0.6642150900524303,0.6642150900524303,2.8157767839559593,1.6444566286616846,1.4494309133701686,-0.01690917370953021,0.13563368348203628,0.027163091494653614,3.482324846985818,2.917749605386218,-0.7574012545226345,1.3322253587909487 3430 Peptidase activity 32 117 2.633253258997587 0.0084571259483139 P55786,Q16740,Q9UIQ6,Q8TCT9,Q6NTF9,Q13867,P42574,P42892,P67812,P60900,P42785,Q9H3G5,O43292,P49721,Q9HB40,Q9UPU5,Q92643,Q969V3,P28072,P14735,O75844,Q5JRX3,P28074,Q92820,Q70CQ2,P22695,O14773,P10619,Q99797,Q14674,Q9NZ08,Q96FZ2 Functions GO Molecular function msigdb_gomf 128,7,143,274,541,402,537,161,35,168,47,49,177,54,55,326,588,461,200,330,81,609,341,615,358,106,110,113,384,513,386,515 1409,1942,110,1276,177,2098,2900,81,936,2259,2292,1209,732,2863,2390,1337,113,3097,3074,330,3280,597,106,2748,942,200,341,3298,1954,3334,2545,1522,2218,537,47,161,2301,2452,1171,54,2828,646,2169,2224,2587,2870,1751,128,168,2797,35,1298,3336,1137,1965,402,513,2235,688,7,1435,1652,1580,609,2237,1491,541,1914,1067,358,3174,1537,909,1584,2127,1186,274,717,588,615,2074,1815,1073,1397,461,2888,1355,1592,515,916,804,1449,2032,670,1925,3318,384,3319,672,1664,49,2248,1235,1819,55,3106,2613,1010,2090,386,143,326,892,1157,1883,2155,2899 0.005176812076117423,-0.22034471621492466,2.360226918485896,0.07084055395748909,1.6603878760836814,-0.2901087935675131,-0.7316181307528602,2.7510864124399865,0.2627094020641012,-0.36090298236806184,-0.38473594847995757,0.11413110287400714,0.406945511095729,-0.7059762210511288,-0.4327622425712757,0.04905067418434559,2.3322196827838484,-0.8884981438055674,-0.8619817453617755,0.9638324211451322,-1.1906923971648218,0.5273305006198339,2.4019708945127647,-0.6298806123677426,0.2627094020641012,1.5478468035966713,0.9273312549578325,-1.2191778402877913,-0.22034471621492466,-1.3349373118137702,-0.5057234167351391,-0.03909589167063334,-0.3371883420413084,0.6060065128039738,3.3551136813137883,1.8325459149864132,-0.38473594847995757,-0.4569583228314796,0.13563368348203628,3.1890088557974594,-0.6804737926663148,0.487523996503178,-0.31359071053648363,-0.3371883420413084,-0.5302953342350691,-0.7059762210511288,-0.12887118746947637,2.1755552047661753,1.7861436228413008,-0.6551091457204445,3.527894748469767,0.07084055395748909,-1.3349373118137702,0.15704238472925763,-0.22034471621492466,0.7974789711276091,0.6448869477951056,-0.3371883420413084,0.447397619113444,4.517401396572567,0.005176812076117423,-0.08377571033449493,-0.061384384139230704,0.5273305006198339,-0.3371883420413084,-0.01690917370953021,0.6060065128039738,-0.19731314994998111,0.19958181332532843,0.8905672747951905,-0.9961073484547495,-0.03909589167063334,0.28357365910325655,-0.061384384139230704,-0.2901087935675131,0.13563368348203628,1.1775484830852023,0.4272126540305929,0.5471155860670778,0.5273305006198339,-0.2667413189986047,-0.151577544698465,0.19958181332532843,0.027163091494653614,0.7026504351173741,-0.7059762210511288,0.04905067418434559,-0.061384384139230704,0.6448869477951056,0.28357365910325655,0.3661616464083245,0.005176812076117423,-0.24348703633272678,0.4675011541744141,-0.19731314994998111,-1.2766888241918128,0.8349190753908383,-1.2766888241918128,0.4675011541744141,-0.08377571033449493,3.3551136813137883,-0.3371883420413084,0.11413110287400714,-0.151577544698465,3.1769568474904344,-0.8884981438055674,-0.5302953342350691,0.24175657929060165,-0.2667413189986047,0.8349190753908383,2.0290981867058675,1.000074973722675,0.3043501904123781,0.15704238472925763,-0.17439114903384173,-0.2901087935675131,-0.7059762210511288 3430 Azurophil granule 23 70 2.6277357303708744 0.0085955263352812 P15289,Q07065,Q13277,O75165,P06280,P11279,O15400,P16278,Q9H7Z7,P42785,Q8NF37,O43681,Q99536,P13473,O15260,Q9NQX7,P07602,P10253,Q9BRF8,P17900,Q9BTY2,P10619,Q9NZJ7 Localization GO Cellular component msigdb_gocc 374,256,260,506,389,413,532,38,172,47,568,428,316,196,319,203,77,349,360,104,361,113,243 815,699,1560,319,532,428,1621,3266,506,1677,2582,389,1336,2785,1090,77,3011,1415,349,113,1282,413,196,374,642,38,104,1476,2167,2398,47,1635,3022,3152,1684,1174,1637,2359,2716,1846,1482,1530,950,1294,2831,2460,256,1431,260,794,881,2762,568,717,615,3206,1188,2423,316,3319,360,361,1150,172,203,2092,243,1876,1938,1201 0.3456433744169804,0.4272126540305929,-0.061384384139230704,1.000074973722675,0.6060065128039738,0.7407953762815624,-0.08377571033449493,-1.1623836255706177,0.6448869477951056,-0.10627094673633292,-0.5302953342350691,0.816233531485841,0.04905067418434559,-0.6551091457204445,0.17835812614782434,2.8157767839559593,-0.8093982448803362,0.005176812076117423,0.9089823832894932,2.3322196827838484,0.07084055395748909,0.7786548166059916,1.5640718300941014,0.8349190753908383,0.487523996503178,3.5165359909007803,2.4571398271524862,-0.01690917370953021,-0.31359071053648363,-0.4327622425712757,3.3551136813137883,-0.08377571033449493,-0.8093982448803362,-0.9689694457036316,-0.10627094673633292,0.13563368348203628,-0.08377571033449493,-0.40868858056019347,-0.6047865559806115,-0.17439114903384173,-0.01690917370953021,-0.03909589167063334,0.2627094020641012,0.07084055395748909,-0.6804737926663148,-0.4569583228314796,1.2468635762934643,0.005176812076117423,1.2296215579874639,0.3661616464083245,0.3043501904123781,-0.6298806123677426,0.5668228264787173,0.4272126540305929,0.5273305006198339,-1.0508669815631295,0.13563368348203628,-0.4327622425712757,1.0181005541038732,-1.2766888241918128,0.8905672747951905,0.8905672747951905,0.15704238472925763,1.7236380473068795,1.5315716196659703,-0.2667413189986047,1.3322253587909487,-0.17439114903384173,-0.19731314994998111,0.13563368348203628 3430 Vesicle membrane 68 273 2.6243402327783265 0.0086817012682871 P35613,P30519,Q13546,P55899,P24390,Q9Y3B3,P01889,O75165,O60831,Q93050,Q07065,P42858,Q13277,Q9Y5X3,P55011,Q9UIQ6,Q8IV08,P17931,Q14108,O00461,Q96DM3,P20020,P11279,Q15043,Q8N511,P42892,O15400,O15127,Q96RL7,Q9UL01,Q9Y287,Q9Y6B6,Q14849,Q15904,Q13190,P42785,Q9Y5X2,P0DP25,Q15057,Q8NF37,Q14728,Q9H223,P20337,O43731,P49755,Q5T9L3,P61020,Q03519,P13473,O15260,Q8WTV0,Q9NQX7,Q7Z3C6,P07602,Q969Q5,O76024,A4D1P6,Q03518,O00264,Q9Y487,P10253,O15118,O00203,Q15907,Q15363,P50570,Q9NZJ7,Q9NR31 Localization GO Cellular component msigdb_gocc 375,1,512,511,4,133,507,506,505,136,256,259,260,270,394,143,273,523,22,23,546,278,413,415,32,161,532,163,292,557,166,300,43,434,301,47,573,304,312,568,565,313,562,59,315,192,447,198,196,319,71,203,459,77,207,455,334,86,216,94,349,98,483,111,241,491,243,248 334,1730,483,216,2817,1367,23,1275,659,2740,867,930,678,2158,98,163,319,532,727,1019,3149,59,1465,1618,1468,2343,2437,622,2099,932,1784,1621,505,3266,1368,506,1674,2160,785,1737,624,455,2103,2104,2781,1125,2498,1208,561,1676,507,732,1890,684,2665,3234,2785,77,3372,3217,3151,3235,304,349,1210,2295,2442,413,2210,1742,196,1892,523,278,2909,562,1024,1567,2109,4,3395,3334,1,3197,3076,2980,1341,375,2398,2218,2299,2793,47,259,161,1096,1250,874,315,491,1684,1685,3153,1524,1174,2114,1029,1480,2673,394,511,2871,447,789,1346,2360,2798,1641,2721,664,1379,1689,2677,2061,1380,1531,1294,649,86,198,256,2266,1429,1381,2013,1695,1964,766,301,260,1179,512,1138,1802,1139,2232,2175,22,2559,1142,768,1578,565,43,415,312,3158,2018,1434,1064,241,990,2988,434,111,608,769,798,192,2023,881,1970,1068,1183,459,3100,992,714,3284,273,1394,32,1977,2129,568,1588,71,1446,717,801,3119,1313,136,207,1231,3206,1816,546,2731,632,2029,1232,2193,2483,292,1315,1501,633,1452,1769,3319,3245,1005,3427,1717,2139,3369,1150,313,1008,1320,1505,3121,1871,203,248,2089,1875,2197,243,3005,1876,1989,1012,1824,1508,1360,1825,3412,1406,1119,143,3086,1462,2530,2286,557,2039,2253,2737,1014,3165,2288,2200,1608,1121,166,2815,3166,784,133,94,639,698,2384,573,270,811,3330,300,2203,895,1328 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236806184,-0.31359071053648363,-0.061384384139230704,0.17835812614782434,1.8016559746006866,-0.6551091457204445,-0.9689694457036316,0.3865954317326442,2.1610865858455655,2.6060641851362782,0.5074668730496471,0.447397619113444,-0.40868858056019347,0.5668228264787173,1.1949644490190432,0.3661616464083245,-1.3057195477388794,1.0895765601315317,-0.31359071053648363,0.3043501904123781,0.07084055395748909 3430 transporter 19 56 2.617816657038192 0.0088494338406557 P55060,Q9HD45,Q9Y619,Q9H2V7,Q567V2,O43772,P52292,O60830,Q9C0E2,Q9NR77,Q96P70,O43681,Q99595,Q9Y584,Q92973,O15397,Q9H2D1,Q9UJZ1,Q15070 Functions Panther Protein class panther_protein_class 510,129,266,148,150,152,156,30,417,297,176,428,56,62,460,340,120,520,126 2257,1943,1831,659,1123,1464,340,728,428,152,2940,30,3180,759,2056,3050,873,2547,156,3131,2587,1290,509,901,510,2507,2012,1644,3133,126,150,3368,2479,1585,1445,2690,828,629,460,176,2137,56,2963,3162,417,120,148,859,129,297,838,2427,520,62,1728,266 -0.36090298236806184,-0.22034471621492466,-0.17439114903384173,0.4675011541744141,0.15704238472925763,-0.01690917370953021,0.9273312549578325,0.406945511095729,0.7407953762815624,1.8937948621783494,-0.7574012545226345,3.684618516209035,-1.023405807478901,0.3865954317326442,-0.2667413189986047,-0.8356157493053581,0.3043501904123781,-0.5057234167351391,1.8632581140200792,-0.9419899846973533,-0.5302953342350691,0.07084055395748909,0.6448869477951056,0.28357365910325655,0.6448869477951056,-0.4812782346091039,-0.24348703633272678,-0.08377571033449493,-0.9419899846973533,2.1899853400179143,1.9241584043171278,-1.4839299067547875,-0.4569583228314796,-0.061384384139230704,0.005176812076117423,-0.5798253703616462,0.3456433744169804,0.5074668730496471,0.7026504351173741,1.692107285757572,-0.2901087935675131,3.1648792186751504,-0.7574012545226345,-0.9689694457036316,0.7786548166059916,2.2615667415404976,1.9392759124745347,0.32503982365867656,2.1755552047661753,1.0895765601315317,0.3456433744169804,-0.4327622425712757,0.6448869477951056,3.0796079772709244,-0.10627094673633292,1.2123219939175685 3430 Primary active transmembrane transporter activity 20 56 2.617684193194098 0.00885286950304 Q9NUT2,Q9HD20,P14854,Q9P0J0,P20020,O43676,P13073,P08183,P47985,Q03519,P03886,Q9Y6M9,P51798,P00403,Q03518,Q9UDW1,O14678,Q15388,P16615,Q7KZN9 Functions GO Molecular function msigdb_gomf 398,137,392,149,278,25,178,429,191,198,74,482,335,213,86,92,222,355,249,257 1086,1941,222,1019,25,2975,623,2387,1206,3093,681,2438,839,3215,2620,978,213,74,897,536,429,1245,1739,178,392,249,3048,278,2296,1475,3333,1049,1286,3112,1051,1094,2546,191,3362,335,492,2360,86,198,355,2837,905,257,137,2574,398,149,92,2491,639,482 0.17835812614782434,-0.22034471621492466,1.4328472746723286,0.22071433819033928,3.8372261164826145,-0.7833273588538234,0.5074668730496471,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.28357365910325655,0.6060065128039738,0.7407953762815624,0.09253370913532158,-0.12887118746947637,1.6603878760836814,0.816233531485841,1.2640484788395443,-0.8356157493053581,1.1600736506845353,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,0.19958181332532843,0.07084055395748909,-0.9151668939436284,0.19958181332532843,0.17835812614782434,-0.5057234167351391,1.5963727964305452,-1.4537345413628453,0.945614424806558,0.6642150900524303,-0.40868858056019347,2.672453216244307,1.5640718300941014,0.8905672747951905,-0.6804737926663148,0.28357365910325655,1.2468635762934643,2.1028225946561765,-0.5057234167351391,0.816233531485841,1.9392759124745347,2.6194057651180533,-0.4569583228314796,0.5074668730496471,0.6834693746272135 3430 Lipid transporter activity 12 23 2.615097203696408 0.0089202065295559 Q9BXW6,O15118,O14678,P11166,P17900,O14975,Q14849,P30536,Q7Z3C6,Q4KMQ2,Q96GC9,P08183 Functions GO Molecular function msigdb_gomf 324,98,222,595,104,678,43,12,459,608,569,429 2739,222,678,98,429,595,104,1248,1286,12,873,1482,1294,43,608,3187,459,569,1315,1717,324,746,2034 -0.6298806123677426,1.4328472746723286,0.447397619113444,2.5388692262913795,0.7407953762815624,0.5273305006198339,2.4571398271524862,0.09253370913532158,0.07084055395748909,4.222429217331235,0.3043501904123781,-0.01690917370953021,0.07084055395748909,3.413286496271575,0.5273305006198339,-1.023405807478901,0.7026504351173741,0.5668228264787173,0.07084055395748909,-0.10627094673633292,1.000074973722675,0.406945511095729,-0.24348703633272678 3430 Cardiac muscle contraction 7 21 2.6134710558876977 0.0089627675032877 P14406,P22695,P13073,O14949,P00403,Q9UDW1,P47985 Processes and pathways KEGG Pathways msigdb_kegg 9,106,178,82,213,92,191 82,213,897,2745,1245,733,2666,1739,178,9,392,3127,3128,249,2296,106,1051,191,2170,1848,92 2.7380578010529537,1.4659622290827485,0.28357365910325655,-0.6298806123677426,0.09253370913532158,0.406945511095729,-0.5798253703616462,-0.12887118746947637,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,1.2640484788395443,-0.38473594847995757,2.4019708945127647,0.19958181332532843,1.5963727964305452,-0.31359071053648363,-0.17439114903384173,2.6194057651180533 3430 Protein localization to endoplasmic reticulum 7 36 2.613276500055603 0.0089678717178396 P46379,P24390,O43292,Q9Y5M8,Q15629,O43731,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 121,4,177,180,89,59,127 2158,816,177,428,59,1514,550,2209,1417,4,2670,121,2453,1376,3356,1799,2797,2718,789,2012,879,688,710,89,1703,478,1447,281,1113,1009,127,1876,1509,1154,1510,180 -0.31359071053648363,0.3456433744169804,1.6603878760836814,0.7407953762815624,3.104102422844003,-0.03909589167063334,0.5864529093583782,-0.3371883420413084,0.005176812076117423,4.687680585731818,-0.5798253703616462,2.247325615021821,-0.4569583228314796,0.027163091494653614,-1.4237405696271823,-0.151577544698465,-0.6551091457204445,-0.6047865559806115,0.3661616464083245,-0.24348703633272678,0.3043501904123781,0.447397619113444,0.4272126540305929,2.632715285689517,-0.10627094673633292,0.6834693746272135,0.005176812076117423,1.1600736506845353,0.17835812614782434,0.24175657929060165,2.1899853400179143,-0.17439114903384173,-0.01690917370953021,0.15704238472925763,-0.01690917370953021,1.6603878760836814 3430 Amyloid precursor protein metabolic process 6 20 2.613138084636643 0.0089715046566896 Q15392,Q9Y287,O95197,Q9NQX7,Q96P70,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 2,166,42,203,176,127 1623,42,1520,985,537,315,2009,3377,1382,2512,1142,2,717,2322,176,1450,127,203,2091,166 -0.08377571033449493,3.4479092742401036,-0.03909589167063334,0.24175657929060165,0.6060065128039738,1.0181005541038732,-0.24348703633272678,-1.5757554991734064,0.027163091494653614,-0.4812782346091039,0.15704238472925763,4.706308247813215,0.4272126540305929,-0.38473594847995757,1.692107285757572,0.005176812076117423,2.1899853400179143,1.5315716196659703,-0.2667413189986047,1.8016559746006866 3430 Nucleotide transmembrane transport 6 8 2.609462357096971 0.0090684622657919 Q9BSK2,Q8TB61,O43808,Q9H2D1,P12236,P12235 Processes and pathways GO Biological process msigdb_gobp 165,39,486,120,218,182 486,488,182,218,1393,39,165,120 0.6642150900524303,0.6642150900524303,1.6444566286616846,1.4494309133701686,0.027163091494653614,3.482324846985818,1.8171233074337798,2.2615667415404976 3430 Autophagy of mitochondrion 11 33 2.600845443468054 0.0092994340092342 P42858,P04062,P30536,Q7Z3C6,Q9UBN7,P52789,Q9BWH2,P27544,P21796,Q99623,P12235 Processes and pathways GO Biological process msigdb_gobp 259,68,12,459,439,236,454,239,20,383,182 1613,1367,1413,68,2784,488,182,1630,20,239,12,259,2009,601,236,1799,2917,768,824,1183,1069,459,667,2184,3318,383,454,2330,1873,439,2149,1883,2382 -0.08377571033449493,0.027163091494653614,0.005176812076117423,2.993031551841918,-0.6551091457204445,0.6642150900524303,1.6444566286616846,-0.08377571033449493,3.9859536481432736,1.3491309609547064,4.222429217331235,1.2296215579874639,-0.24348703633272678,0.5273305006198339,1.382778649014379,-0.151577544698465,-0.7316181307528602,0.3865954317326442,0.3456433744169804,0.13563368348203628,0.19958181332532843,0.7026504351173741,0.4675011541744141,-0.31359071053648363,-1.2766888241918128,0.8349190753908383,0.7217588966997998,-0.38473594847995757,-0.17439114903384173,0.7407953762815624,-0.2901087935675131,-0.17439114903384173,-0.40868858056019347 3430 Electron transport chain oxphos system in mitochondria 19 52 2.5969611784551474 0.0094052553400842 P14406,P14854,O43676,P21912,O75964,P13073,P24539,P12235,P47985,P56385,P03886,O14949,Q9Y6M9,P00403,P12236,Q9UDW1,P22695,P51970,Q7KZN9 Processes and pathways WikiPathways msigdb_wp 9,392,25,282,33,178,183,182,191,446,74,82,482,213,218,92,106,492,257 1086,1941,82,25,2975,2387,1206,3093,681,2438,935,3268,33,839,3215,2620,978,213,74,488,536,2666,1739,182,218,178,9,392,3127,3128,3048,2296,282,106,183,2214,3112,2866,1051,2001,191,3255,3362,492,2588,446,2837,905,257,92,2149,482 0.17835812614782434,-0.22034471621492466,2.7380578010529537,3.8372261164826145,-0.7833273588538234,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,0.2627094020641012,-1.1623836255706177,3.5731076371518076,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.6642150900524303,0.6060065128039738,-0.5798253703616462,-0.12887118746947637,1.6444566286616846,1.4494309133701686,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,-0.8356157493053581,-0.38473594847995757,1.1425395010761892,2.4019708945127647,1.6444566286616846,-0.3371883420413084,-0.9151668939436284,-0.7059762210511288,0.19958181332532843,-0.24348703633272678,1.5963727964305452,-1.1342490728645735,-1.4537345413628453,0.6642150900524303,-0.5302953342350691,0.7217588966997998,-0.6804737926663148,0.28357365910325655,1.2468635762934643,2.6194057651180533,-0.2901087935675131,0.6834693746272135 3430 Glycosylation 18 47 2.5918043391470205 0.0095474053888786 O60502,O15118,Q16706,Q10472,Q9Y5P6,P04062,O60512,P46977,Q96L58,Q9H9S5,Q9BT22,O75503,Q86YN1,Q6ZXV5,Q8NAT1,Q8N4A0,O43505,Q2TAA5 Processes and pathways GO Biological process msigdb_gobp 223,98,554,320,591,68,231,598,234,411,371,116,185,477,544,153,246,403 2818,98,2776,246,1277,621,223,231,1204,1998,1674,116,2162,68,1627,1281,2398,598,2633,1752,2551,1577,1430,821,320,1487,2559,554,403,477,2805,185,153,544,1112,234,1036,371,1150,2036,3358,411,2573,1822,1933,969,591 -0.6804737926663148,2.5388692262913795,-0.6551091457204445,1.2811766906485145,0.07084055395748909,0.5074668730496471,1.4328472746723286,1.3995215238872651,0.11413110287400714,-0.24348703633272678,-0.10627094673633292,2.3181620708424706,-0.31359071053648363,2.993031551841918,-0.08377571033449493,0.07084055395748909,-0.4327622425712757,0.5273305006198339,-0.5549954789805401,-0.12887118746947637,-0.5057234167351391,-0.061384384139230704,0.005176812076117423,0.3456433744169804,1.000074973722675,-0.01690917370953021,-0.5057234167351391,0.5864529093583782,0.7974789711276091,0.6834693746272135,-0.6551091457204445,1.6444566286616846,1.8937948621783494,0.6060065128039738,0.17835812614782434,1.3995215238872651,0.22071433819033928,0.8535361731217637,0.15704238472925763,-0.24348703633272678,-1.4237405696271823,0.7974789711276091,-0.5057234167351391,-0.151577544698465,-0.19731314994998111,0.2627094020641012,0.5471155860670778 3430 Regulation of macroautophagy 19 61 2.579213220662226 0.0099025643033912 P54646,P42858,Q93050,Q9Y5X3,P09601,P46934,P21796,Q9BQS8,Q15382,Q9UBN7,P12235,P04062,O15269,Q9Y487,P42345,O15118,Q8TBX8,P27544,P05141 Processes and pathways GO Biological process msigdb_gobp 254,259,136,270,17,524,20,408,290,439,182,68,441,94,354,98,112,239,488 2704,98,441,1673,3149,785,1737,1125,3193,68,2622,2863,2784,488,2390,2346,17,182,2536,2746,1475,3333,20,2445,239,1094,2546,354,537,259,524,254,2360,1101,582,768,710,290,1536,1183,1497,112,2132,136,803,2371,2483,1452,408,1009,2330,2967,439,2491,1608,725,1776,1828,94,639,270 -0.6047865559806115,2.5388692262913795,0.7217588966997998,-0.10627094673633292,-0.9689694457036316,0.3661616464083245,-0.12887118746947637,0.15704238472925763,-1.0508669815631295,2.993031551841918,-0.5549954789805401,-0.7059762210511288,-0.6551091457204445,0.6642150900524303,-0.4327622425712757,-0.40868858056019347,4.05893051652828,1.6444566286616846,-0.5057234167351391,-0.6298806123677426,-0.01690917370953021,-1.3349373118137702,3.9859536481432736,-0.4569583228314796,1.3491309609547064,0.17835812614782434,-0.5057234167351391,0.8905672747951905,0.6060065128039738,1.2296215579874639,0.6254843056815558,1.2468635762934643,-0.40868858056019347,0.17835812614782434,0.5471155860670778,0.3865954317326442,0.4272126540305929,1.1249455781236504,-0.03909589167063334,0.13563368348203628,-0.01690917370953021,2.34624122931555,-0.2901087935675131,2.1174474931929272,0.3661616464083245,-0.40868858056019347,-0.4569583228314796,0.005176812076117423,0.7974789711276091,0.24175657929060165,-0.38473594847995757,-0.7574012545226345,0.7407953762815624,-0.4569583228314796,-0.061384384139230704,0.4272126540305929,-0.12887118746947637,-0.151577544698465,2.6060641851362782,0.5074668730496471,1.1949644490190432 3430 Calmodulin 7 16 2.5789072269811446 0.0099113400978514 P80303,P41208,Q02818,Q14257,P0DP25,Q8IYU8,Q9BRK5 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 0,65,36,233,304,250,160 729,304,2110,65,1686,3183,0,36,233,2681,3203,2183,250,1976,317,160 0.406945511095729,1.0539628363107982,-0.2901087935675131,3.0302984430490625,-0.10627094673633292,-1.023405807478901,5.333361777399175,3.527894748469767,1.3995215238872651,-0.5798253703616462,-1.0508669815631295,-0.31359071053648363,1.2640484788395443,-0.22034471621492466,1.0181005541038732,1.8479240879335823 3430 Intracellular calcium-sensing protein 7 16 2.5789072269811446 0.0099113400978514 P80303,P41208,Q02818,Q14257,P0DP25,Q8IYU8,Q9BRK5 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 0,65,36,233,304,250,160 729,304,2110,65,1686,3183,0,36,233,2681,3203,2183,250,1976,317,160 0.406945511095729,1.0539628363107982,-0.2901087935675131,3.0302984430490625,-0.10627094673633292,-1.023405807478901,5.333361777399175,3.527894748469767,1.3995215238872651,-0.5798253703616462,-1.0508669815631295,-0.31359071053648363,1.2640484788395443,-0.22034471621492466,1.0181005541038732,1.8479240879335823 3430 Macromolecule transmembrane transporter activity 6 13 2.5766564312596985 0.0099761053577105 Q9NS69,Q99595,Q9Y584,O14925,P49755,O60830 Functions GO Molecular function msigdb_gomf 3,56,62,122,315,30 122,30,3150,2293,315,2058,2012,525,355,56,3,1509,62 2.233047134387105,3.684618516209035,-0.9689694457036316,-0.38473594847995757,1.0181005541038732,-0.2667413189986047,-0.24348703633272678,0.6254843056815558,0.8905672747951905,3.1648792186751504,4.706308247813215,-0.01690917370953021,3.0796079772709244 3430 Translocation 8 48 2.5732992187417474 0.0100734076154496 P41208,Q9NS69,Q9BTX1,O60830,Q99595,Q15629,O14925,Q9Y584 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 65,3,105,30,56,89,122,62 1730,122,728,2819,30,549,3180,1837,2056,3050,65,2547,1958,2587,2507,3356,2012,472,1529,1644,89,991,1913,1436,2479,1585,1445,999,2690,2645,2605,1662,1113,2137,56,105,3365,1928,2283,2812,3,2897,2575,3067,62,2618,420,204 -0.12887118746947637,2.233047134387105,0.406945511095729,-0.6804737926663148,3.684618516209035,0.5864529093583782,-1.023405807478901,-0.17439114903384173,-0.2667413189986047,-0.8356157493053581,3.0302984430490625,-0.5057234167351391,-0.22034471621492466,-0.5302953342350691,-0.4812782346091039,-1.4237405696271823,-0.24348703633272678,0.6834693746272135,-0.03909589167063334,-0.08377571033449493,2.632715285689517,0.24175657929060165,-0.19731314994998111,0.005176812076117423,-0.4569583228314796,-0.061384384139230704,0.005176812076117423,0.24175657929060165,-0.5798253703616462,-0.5549954789805401,-0.5302953342350691,-0.08377571033449493,0.17835812614782434,-0.2901087935675131,3.1648792186751504,2.4296246565022512,-1.4537345413628453,-0.19731314994998111,-0.36090298236806184,-0.6551091457204445,4.706308247813215,-0.7059762210511288,-0.5057234167351391,-0.8356157493053581,3.0796079772709244,-0.5302953342350691,0.7786548166059916,1.5315716196659703 3430 Mitochondrial calcium ion transport 7 15 2.572550449982171 0.0100952241441689 Q9Y277,Q8NE86,Q8IYU8,P45880,P21796,Q99623,O95202 Processes and pathways Reactome Pathways msigdb_reactome 294,425,250,13,20,383,154 2900,154,20,1955,13,1298,250,425,1352,2073,2032,383,520,294,2155 -0.7316181307528602,1.8785482781004688,3.9859536481432736,-0.22034471621492466,4.222429217331235,0.07084055395748909,1.2640484788395443,0.7597604826477616,0.04905067418434559,-0.2667413189986047,-0.24348703633272678,0.8349190753908383,0.6448869477951056,1.107291420206707,-0.2901087935675131 3430 Abnormality of head blood vessel 9 25 2.570869289662133 0.01014436068556 Q13510,P16278,P17900,P03886,Q9Y4P3,P07602,P10619,Q9NZJ7,P48651 Drugs and Diseases Human Phenotype Ontology msigdb_hp 158,38,104,74,269,77,113,243,431 2937,1087,2660,1243,74,1336,77,3011,113,2107,38,104,1418,445,2543,431,2673,2872,158,1223,2074,2522,243,2378,269 -0.7574012545226345,0.17835812614782434,-0.5798253703616462,0.09253370913532158,2.86699521405523,0.04905067418434559,2.8157767839559593,-0.8093982448803362,2.3322196827838484,-0.2901087935675131,3.5165359909007803,2.4571398271524862,0.005176812076117423,0.7217588966997998,-0.5057234167351391,0.7407953762815624,-0.5798253703616462,-0.7059762210511288,1.8479240879335823,0.11413110287400714,-0.2667413189986047,-0.4812782346091039,1.3322253587909487,-0.40868858056019347,1.1949644490190432 3430 Golgi cisterna membrane 7 18 2.569638394144224 0.0101804719135689 O60512,Q9Y6B6,Q96L58,Q9H4A6,Q15363,Q8NBN3,O00461 Localization GO Cellular component msigdb_gocc 231,300,234,268,241,212,23 23,231,2049,1376,3025,1430,821,320,1298,241,212,2132,234,2764,633,268,2039,300 3.9438430597865275,1.3995215238872651,-0.2667413189986047,0.027163091494653614,-0.8093982448803362,0.005176812076117423,0.3456433744169804,1.000074973722675,0.07084055395748909,1.3491309609547064,1.482441592729086,-0.2901087935675131,1.3995215238872651,-0.6298806123677426,0.5074668730496471,1.1949644490190432,-0.24348703633272678,1.0895765601315317 3430 Mitochondrial nucleotide transporter subfamily 6 8 2.5647634906472168 0.0103246154280309 Q70HW3,Q9BSK2,O43808,Q9H2D1,P12236,P12235 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 97,165,486,120,218,182 486,488,182,218,1182,97,165,120 0.6642150900524303,0.6642150900524303,1.6444566286616846,1.4494309133701686,0.13563368348203628,2.552373754198136,1.8171233074337798,2.2615667415404976 3430 Electron transport 14 46 2.5593774940444898 0.0104859806752075 Q9H1E5,Q96CU9,O43169,P03886,P22695,Q9UDW1,O43396,O14949,Q9P0J0,P00403,Q6DKK2,O43676,Q86Y39,P47985 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 99,263,10,74,106,92,144,82,149,213,280,25,188,191 1086,1941,82,10,144,25,2975,2387,1206,3093,681,2438,839,3215,2620,388,978,213,74,1245,3380,3127,3048,282,2790,106,3112,2866,1051,3316,191,3362,492,539,2837,905,2268,280,188,263,2997,99,418,149,92,482 0.17835812614782434,-0.22034471621492466,2.7380578010529537,4.3124581612681805,2.0142315842992913,3.8372261164826145,-0.7833273588538234,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.816233531485841,0.24175657929060165,1.4659622290827485,2.86699521405523,0.09253370913532158,-1.6067879521771078,-0.9419899846973533,-0.8356157493053581,1.1425395010761892,-0.6551091457204445,2.4019708945127647,-0.9151668939436284,-0.7059762210511288,0.19958181332532843,-1.2766888241918128,1.5963727964305452,-1.4537345413628453,0.6642150900524303,0.6060065128039738,-0.6804737926663148,0.28357365910325655,-0.36090298236806184,1.1600736506845353,1.6124494198193353,1.2296215579874639,-0.7833273588538234,2.5388692262913795,0.7786548166059916,1.9392759124745347,2.6194057651180533,0.6834693746272135 3430 Cytochrome complex assembly 6 12 2.558428109322461 0.0105146558338442 Q7KZN9,Q9BSK2,Q69YU5,Q9Y2R0,Q15070,P47985 Processes and pathways GO Biological process msigdb_gobp 257,165,11,76,126,191 533,935,191,686,126,11,280,257,165,3004,1609,76 0.6060065128039738,0.2627094020641012,1.5963727964305452,0.447397619113444,2.1899853400179143,4.282599323100913,1.1600736506845353,1.2468635762934643,1.8171233074337798,-0.7833273588538234,-0.061384384139230704,2.854234483045071 3430 Localization within membrane 46 191 2.555393968608612 0.0106067671016356 P35613,Q9HD45,Q9NS69,Q13277,Q9HD20,O60725,Q9H4A6,Q13641,O43805,P17931,Q9P0J0,P43307,O75955,P57105,O15400,Q9Y512,Q9Y5J9,Q15041,O76094,Q15904,P0DP25,P49354,Q15057,Q9H223,O43681,Q9Y584,Q96A33,O14737,Q9Y5L4,P07602,Q99959,Q7L5D6,O00264,Q15629,O15118,Q9BTX1,O00203,Q15907,Q15363,Q96KP1,Q9NZJ7,Q07812,P50570,P46379,Q9NPA0,Q15070 Processes and pathways GO Biological process msigdb_gobp 375,129,3,260,137,141,268,526,387,523,149,28,534,162,532,419,420,424,550,434,304,306,312,313,428,62,323,329,204,77,333,478,216,89,98,105,483,111,241,370,243,368,491,121,519,126 1730,483,216,1731,815,659,329,3148,930,1779,2158,98,816,532,428,1514,387,2343,141,1205,1623,1736,1737,2388,3180,817,534,550,3150,1125,3295,1788,2665,77,1161,2209,304,2442,1792,1472,523,3253,562,3219,1049,1953,2215,2351,1420,2867,898,3348,375,2397,2670,842,1795,2793,28,3335,121,2505,306,2453,1479,491,1685,3153,2170,1345,162,3356,3183,2871,2718,789,1346,2012,2721,1689,2677,2635,1380,582,1531,1532,368,2266,1429,1645,766,1852,260,2556,1382,2512,526,708,3271,1220,1142,3026,3027,1909,3282,424,710,312,126,2018,1434,1064,241,990,89,434,111,1652,797,1104,1702,2023,478,2479,3284,2365,1497,1394,2242,1712,3329,2130,1352,629,323,803,2076,1816,3102,370,1232,2483,1113,333,105,922,313,1009,2928,268,1505,2325,3121,137,129,924,519,2735,963,2250,3,1873,243,1195,149,1825,1509,1154,1933,1934,1462,2530,2428,3165,2288,1121,1510,1198,725,1609,1408,1361,1828,2431,1611,2341,419,62,2618,420,204 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3430 Abnormal retinal artery morphology 7 22 2.5535590594389923 0.0106628193662718 Q13510,P16278,P17900,P03886,P07602,P10619,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 158,38,104,74,77,113,243 2937,2660,1243,74,1336,77,3011,113,2107,38,104,445,2543,2673,2872,158,1223,2074,2522,243,2378,269 -0.7574012545226345,-0.5798253703616462,0.09253370913532158,2.86699521405523,0.04905067418434559,2.8157767839559593,-0.8093982448803362,2.3322196827838484,-0.2901087935675131,3.5165359909007803,2.4571398271524862,0.7217588966997998,-0.5057234167351391,-0.5798253703616462,-0.7059762210511288,1.8479240879335823,0.11413110287400714,-0.2667413189986047,-0.4812782346091039,1.3322253587909487,-0.40868858056019347,1.1949644490190432 3430 Alcohol metabolic process 21 87 2.548076989426376 0.010831856310193 P54646,Q15392,Q9BQE5,Q14534,Q16850,Q13510,O76062,Q14849,Q06520,P00374,P48449,P16435,Q14739,P04062,Q8WTV0,P51648,P05067,O15118,Q15800,P49748,P37268 Processes and pathways GO Biological process msigdb_gobp 254,2,15,272,146,158,164,43,174,52,184,310,311,68,71,79,224,98,101,232,123 3389,98,441,1673,3092,2778,1998,1785,468,1332,164,640,2977,3322,52,1677,68,224,2744,3236,2583,1128,2348,2788,310,1247,1743,2790,563,3315,2868,985,123,1343,3019,2003,184,1421,232,3256,1344,2951,2714,79,1637,3418,254,2632,3374,2303,1482,2062,3024,3156,649,174,1298,158,3239,2175,3132,272,311,43,2725,2,1259,101,2267,146,2407,380,1658,716,912,71,2193,3318,3227,15,1040,324,1236,438,2339,1272,638 -1.6695089416562565,2.5388692262913795,0.7217588966997998,-0.10627094673633292,-0.8884981438055674,-0.6551091457204445,-0.24348703633272678,-0.151577544698465,0.6834693746272135,0.04905067418434559,1.8171233074337798,0.487523996503178,-0.7833273588538234,-1.3057195477388794,3.2607896593204937,-0.10627094673633292,2.993031551841918,1.4328472746723286,-0.6298806123677426,-1.1062863390031978,-0.5302953342350691,0.15704238472925763,-0.40868858056019347,-0.6551091457204445,1.036063009474167,0.09253370913532158,-0.12887118746947637,-0.6551091457204445,0.5668228264787173,-1.2766888241918128,-0.7059762210511288,0.24175657929060165,2.2187310778900433,0.04905067418434559,-0.8093982448803362,-0.24348703633272678,1.6444566286616846,0.005176812076117423,1.3995215238872651,-1.1342490728645735,0.04905067418434559,-0.7574012545226345,-0.6047865559806115,2.777052623692763,-0.08377571033449493,-2.614938713691235,1.2468635762934643,-0.5549954789805401,-1.5449371974827035,-0.38473594847995757,-0.01690917370953021,-0.2667413189986047,-0.8093982448803362,-0.9689694457036316,0.487523996503178,1.7078960893112645,0.07084055395748909,1.8479240879335823,-1.1062863390031978,-0.31359071053648363,-0.9419899846973533,1.1775484830852023,1.036063009474167,3.413286496271575,-0.6047865559806115,4.706308247813215,0.09253370913532158,2.5117605953310402,-0.36090298236806184,2.0142315842992913,-0.4327622425712757,0.8349190753908383,-0.08377571033449493,0.4272126540305929,0.28357365910325655,2.917749605386218,-0.31359071053648363,-1.2766888241918128,-1.0784930750204527,4.131016779152228,0.22071433819033928,1.000074973722675,0.11413110287400714,0.7407953762815624,-0.38473594847995757,0.09253370913532158,0.5074668730496471 3430 Glycoprotein biosynthetic process 21 55 2.5464601694248765 0.0108821629551241 Q9H4A6,Q9H9S5,Q8NAT1,Q8N4A0,Q2TAA5,Q16706,Q9Y287,Q9UL01,Q7LGA3,Q86YN1,Q10472,Q9Y5P6,Q9NQX7,Q6ZXV5,O60502,O15118,O60512,P46977,Q96L58,Q9BT22,O43505 Processes and pathways GO Biological process msigdb_gobp 268,411,544,153,403,554,166,557,175,185,320,591,203,477,223,98,231,598,234,371,246 2818,2434,98,2776,246,1277,621,223,231,1204,1783,1998,703,1674,2162,1627,1281,2542,985,2398,598,2633,1752,2551,1577,1430,821,320,1487,2559,554,403,477,175,2805,185,153,544,1112,717,2322,234,371,1150,2036,268,3358,411,203,2091,1822,1933,557,166,591 -0.6804737926663148,-0.4569583228314796,2.5388692262913795,-0.6551091457204445,1.2811766906485145,0.07084055395748909,0.5074668730496471,1.4328472746723286,1.3995215238872651,0.11413110287400714,-0.151577544698465,-0.24348703633272678,0.4272126540305929,-0.10627094673633292,-0.31359071053648363,-0.08377571033449493,0.07084055395748909,-0.5057234167351391,0.24175657929060165,-0.4327622425712757,0.5273305006198339,-0.5549954789805401,-0.12887118746947637,-0.5057234167351391,-0.061384384139230704,0.005176812076117423,0.3456433744169804,1.000074973722675,-0.01690917370953021,-0.5057234167351391,0.5864529093583782,0.7974789711276091,0.6834693746272135,1.692107285757572,-0.6551091457204445,1.6444566286616846,1.8937948621783494,0.6060065128039738,0.17835812614782434,0.4272126540305929,-0.38473594847995757,1.3995215238872651,0.8535361731217637,0.15704238472925763,-0.24348703633272678,1.1949644490190432,-1.4237405696271823,0.7974789711276091,1.5315716196659703,-0.2667413189986047,-0.151577544698465,-0.19731314994998111,0.5864529093583782,1.8016559746006866,0.5471155860670778 3430 EF-hand domain [IPR002048] 14 49 2.546370899845941 0.0108849465783007 P80303,Q9NWM8,P41208,Q02818,O75071,Q14257,Q8IYU8,Q96AY3,P0DP25,O95302,Q9H223,O95202,Q9Y680,Q9BRK5 Sequence InterPro Domain interpro_domain 0,325,65,36,90,233,250,366,304,147,313,154,95,160 1996,729,90,1674,1369,154,147,2863,2390,304,2444,3414,2212,3280,2667,3076,2110,3348,65,2793,2003,1686,0,36,1963,1696,233,3026,2681,379,1182,1973,1543,250,568,1186,366,2275,1448,160,313,1505,325,2426,1013,3412,967,1198,95 -0.24348703633272678,0.406945511095729,2.6194057651180533,-0.10627094673633292,0.027163091494653614,1.8785482781004688,1.9843746291639714,-0.7059762210511288,-0.4327622425712757,1.0539628363107982,-0.4569583228314796,-2.314462314047482,-0.3371883420413084,-1.1906923971648218,-0.5798253703616462,-0.8619817453617755,-0.2901087935675131,-1.3643448569490237,3.0302984430490625,-0.6551091457204445,-0.24348703633272678,-0.10627094673633292,5.333361777399175,3.527894748469767,-0.22034471621492466,-0.10627094673633292,1.3995215238872651,-0.8093982448803362,-0.5798253703616462,0.8349190753908383,0.13563368348203628,-0.22034471621492466,-0.03909589167063334,1.2640484788395443,0.5668228264787173,0.13563368348203628,0.872085387655934,-0.36090298236806184,0.005176812076117423,1.8479240879335823,1.036063009474167,-0.01690917370953021,1.000074973722675,-0.4327622425712757,0.24175657929060165,-2.2062494461722344,0.2627094020641012,0.13563368348203628,2.592690371019141 3430 Bulbar signs 7 13 2.5434216948634667 0.0109772658547664 P15289,P04062,P03886,P07602,Q9NZJ7,Q99720,Q15043 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,68,74,77,243,24,415 428,74,68,2745,77,374,1168,2300,415,2369,24,243,1016 0.7407953762815624,2.86699521405523,2.993031551841918,-0.6298806123677426,2.8157767839559593,0.8349190753908383,0.13563368348203628,-0.38473594847995757,0.7786548166059916,-0.40868858056019347,3.8907768973797325,1.3322253587909487,0.24175657929060165 3430 Protein transmembrane transporter activity 6 12 2.5403989471939954 0.0110726085965673 Q9NS69,Q99595,Q9Y584,O14925,P49755,O60830 Functions GO Molecular function msigdb_gomf 3,56,62,122,315,30 122,30,3150,2293,315,2012,525,355,56,3,1509,62 2.233047134387105,3.684618516209035,-0.9689694457036316,-0.38473594847995757,1.0181005541038732,-0.24348703633272678,0.6254843056815558,0.8905672747951905,3.1648792186751504,4.706308247813215,-0.01690917370953021,3.0796079772709244 3430 Limb undergrowth 16 60 2.538078518859734 0.0111462973561964 Q15392,P42345,Q13535,Q9UHX1,O95613,O15228,O00116,Q9UBN7,Q9P2D1,Q03164,Q13426,Q14739,Q96HY6,O15360,Q15427,Q07864 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,354,230,6,423,421,205,439,339,244,21,311,281,308,91,377 812,205,3147,2097,421,3069,308,1410,1277,2976,1998,1622,2942,1786,1332,423,3012,1740,2536,2746,3219,3347,1522,1288,1169,2749,354,1250,1421,2548,1640,1689,2226,244,377,2014,21,230,1855,311,2,91,1306,2839,1395,2188,2647,281,887,2895,1116,339,3142,438,439,6,1991,1408,928,3109 0.3456433744169804,1.5152459271739311,-0.9689694457036316,-0.2901087935675131,0.7597604826477616,-0.8619817453617755,1.036063009474167,0.005176812076117423,0.07084055395748909,-0.7833273588538234,-0.24348703633272678,-0.08377571033449493,-0.7574012545226345,-0.151577544698465,0.04905067418434559,0.7597604826477616,-0.8093982448803362,-0.12887118746947637,-0.5057234167351391,-0.6298806123677426,-1.0784930750204527,-1.3643448569490237,-0.03909589167063334,0.07084055395748909,0.13563368348203628,-0.6298806123677426,0.8905672747951905,0.09253370913532158,0.005176812076117423,-0.5057234167351391,-0.08377571033449493,-0.10627094673633292,-0.3371883420413084,1.2982486318400348,0.8349190753908383,-0.24348703633272678,3.9859536481432736,1.4162109379313024,-0.17439114903384173,1.036063009474167,4.706308247813215,2.6194057651180533,0.07084055395748909,-0.6804737926663148,0.027163091494653614,-0.31359071053648363,-0.5549954789805401,1.1600736506845353,0.3043501904123781,-0.7059762210511288,0.17835812614782434,0.945614424806558,-0.9419899846973533,0.7407953762815624,0.7407953762815624,4.612592293772992,-0.22034471621492466,0.027163091494653614,0.28357365910325655,-0.8884981438055674 3430 Secretory granule membrane 25 72 2.537658301170275 0.0111596884994786 P35613,P30519,Q07065,Q13277,P01889,O75165,Q93050,P17931,P11279,P42785,Q8NF37,P49755,P61020,P13473,O15260,Q9NQX7,P07602,Q969Q5,Q4KMQ2,O00264,P10253,Q15363,Q9Y5K8,Q9NZJ7,O60645 Localization GO Cellular component msigdb_gocc 375,1,256,260,507,506,136,523,413,47,568,315,447,196,319,203,77,207,608,216,349,241,639,243,622 216,678,319,2437,622,1621,3266,506,624,2104,507,3234,77,349,1210,413,2210,196,1892,523,2909,1,3076,2980,375,2398,47,1096,315,1684,1685,1174,2114,447,789,1346,2798,1689,2061,1380,1294,256,1381,1695,260,1139,2559,1142,241,608,769,798,881,1068,1183,568,1588,717,136,207,3206,3319,2139,1150,1871,203,243,1876,1119,3166,639,2203 1.4494309133701686,0.447397619113444,1.000074973722675,-0.4569583228314796,0.5074668730496471,-0.08377571033449493,-1.1623836255706177,0.6448869477951056,0.5074668730496471,-0.2901087935675131,0.6448869477951056,-1.1062863390031978,2.8157767839559593,0.9089823832894932,0.11413110287400714,0.7786548166059916,-0.3371883420413084,1.5640718300941014,-0.19731314994998111,0.6254843056815558,-0.7316181307528602,5.005721299000376,-0.8619817453617755,-0.7833273588538234,0.8349190753908383,-0.4327622425712757,3.3551136813137883,0.17835812614782434,1.0181005541038732,-0.10627094673633292,-0.10627094673633292,0.13563368348203628,-0.2901087935675131,0.7217588966997998,0.3661616464083245,0.04905067418434559,-0.6551091457204445,-0.10627094673633292,-0.2667413189986047,0.027163091494653614,0.07084055395748909,1.2468635762934643,0.027163091494653614,-0.10627094673633292,1.2296215579874639,0.15704238472925763,-0.5057234167351391,0.15704238472925763,1.3491309609547064,0.5273305006198339,0.3865954317326442,0.3661616464083245,0.3043501904123781,0.19958181332532843,0.13563368348203628,0.5668228264787173,-0.061384384139230704,0.4272126540305929,2.1174474931929272,1.5152459271739311,-1.0508669815631295,-1.2766888241918128,-0.2901087935675131,0.15704238472925763,-0.17439114903384173,1.5315716196659703,1.3322253587909487,-0.17439114903384173,0.17835812614782434,-0.9689694457036316,0.5074668730496471,-0.31359071053648363 3430 Cellular lipid metabolic process 66 221 2.532519738503268 0.0113245993669999 Q6IAN0,P54646,Q8NBX0,Q9P035,P06280,O95864,Q8N4Q0,P07099,Q2TAA5,Q16134,Q13510,P16278,Q9NPH0,P52429,O15228,Q9H7Z7,A8MXV4,Q8NCG7,O43292,P50897,Q8NF37,Q9HB40,P43034,P48449,Q86YN1,P16435,P48651,Q96G23,Q96N66,P23786,O95470,Q8IXJ6,P04062,A1L0T0,Q8WTV0,O15269,Q53GQ0,Q13315,P07602,O00116,P51648,O75844,Q8NCC3,Q9BTU6,Q06136,Q99623,Q15067,P49327,O14678,Q16836,Q15800,O60512,P17900,P49748,Q9NUQ2,Q8TBX8,Q07812,P27544,O43808,Q9NZJ7,Q9BT22,O00767,Q8NHP8,Q6NUM9,Q9UJZ1,P37268 Processes and pathways GO Biological process msigdb_gobp 514,254,135,531,389,388,16,18,403,539,158,38,40,553,421,172,46,302,177,53,568,55,564,184,185,310,431,61,451,63,64,587,68,195,71,441,202,332,77,205,79,81,84,480,87,383,350,471,222,356,101,231,104,232,235,112,368,239,486,243,371,484,119,380,520,123 195,3389,46,205,1940,814,1615,3404,484,222,2434,678,421,680,441,1673,3069,177,486,1833,231,1782,1998,1674,1625,1785,3095,624,2388,81,1332,640,2977,2621,64,1788,3322,388,1738,68,2582,1890,3405,3181,389,1336,18,77,3011,3401,3413,2583,3380,1518,1128,2788,3420,38,310,1247,3280,104,2667,1248,2538,63,3314,2669,239,2710,1286,2824,2167,3376,2261,1842,3315,985,123,3316,1288,1573,1343,1797,2299,3019,564,3391,184,431,471,232,1574,1479,53,2714,79,2302,553,1637,3418,625,254,2912,2830,1482,1294,3156,649,2460,2119,87,368,2266,2063,1298,2801,3411,332,158,2175,3132,708,768,2561,350,1349,652,2725,711,101,539,2267,356,1435,403,1700,202,797,610,825,3339,881,514,380,3187,773,1307,2126,185,587,1442,1443,16,2186,1658,716,135,84,302,568,119,112,912,71,613,1863,588,2807,2188,1074,2371,61,451,2193,2521,3244,2522,1452,383,2849,744,1316,371,480,1927,3427,3399,3403,1267,3209,922,746,834,3358,172,2037,55,2086,40,1236,2331,890,3035,235,675,1041,676,243,531,1876,1118,1878,1933,2285,520,3191,1042,1016,638,1084 1.5640718300941014,-1.6695089416562565,3.3667955634163027,1.5152459271739311,-0.22034471621492466,0.3456433744169804,-0.08377571033449493,-2.0313624559825123,0.6642150900524303,1.4328472746723286,-0.4569583228314796,0.447397619113444,0.7597604826477616,0.447397619113444,0.7217588966997998,-0.10627094673633292,-0.8619817453617755,1.6603878760836814,0.6642150900524303,-0.17439114903384173,1.3995215238872651,-0.151577544698465,-0.24348703633272678,-0.10627094673633292,-0.08377571033449493,-0.151577544698465,-0.8884981438055674,0.5074668730496471,-0.4327622425712757,2.7510864124399865,0.04905067418434559,0.487523996503178,-0.7833273588538234,-0.5549954789805401,3.0426662360183325,-0.151577544698465,-1.3057195477388794,0.816233531485841,-0.12887118746947637,2.993031551841918,-0.5302953342350691,-0.19731314994998111,-2.0313624559825123,-1.023405807478901,0.816233531485841,0.04905067418434559,4.048560352725201,2.8157767839559593,-0.8093982448803362,-1.8631817950549134,-2.242048039872144,-0.5302953342350691,-1.6067879521771078,-0.03909589167063334,0.15704238472925763,-0.6551091457204445,-2.7320450484961065,3.5165359909007803,1.036063009474167,0.09253370913532158,-1.1906923971648218,2.4571398271524862,-0.5798253703616462,0.09253370913532158,-0.5057234167351391,3.0673208707632353,-1.2766888241918128,-0.5798253703616462,1.3491309609547064,-0.6047865559806115,0.07084055395748909,-0.6804737926663148,-0.31359071053648363,-1.5757554991734064,-0.36090298236806184,-0.17439114903384173,-1.2766888241918128,0.24175657929060165,2.2187310778900433,-1.2766888241918128,0.07084055395748909,-0.061384384139230704,0.04905067418434559,-0.151577544698465,-0.38473594847995757,-0.8093982448803362,0.5668228264787173,-1.6695089416562565,1.6444566286616846,0.7407953762815624,0.6834693746272135,1.3995215238872651,-0.061384384139230704,-0.01690917370953021,3.2250123758744826,-0.6047865559806115,2.777052623692763,-0.38473594847995757,0.5864529093583782,-0.08377571033449493,-2.614938713691235,0.5074668730496471,1.2468635762934643,-0.7316181307528602,-0.6804737926663148,-0.01690917370953021,0.07084055395748909,-0.9689694457036316,0.487523996503178,-0.4569583228314796,-0.2901087935675131,2.672453216244307,0.8535361731217637,-0.36090298236806184,-0.2667413189986047,0.07084055395748909,-0.6551091457204445,-2.2062494461722344,0.9638324211451322,1.8479240879335823,-0.31359071053648363,-0.9419899846973533,0.4272126540305929,0.3865954317326442,-0.5057234167351391,0.9089823832894932,0.04905067418434559,0.487523996503178,-0.6047865559806115,0.4272126540305929,2.5117605953310402,0.6060065128039738,-0.36090298236806184,0.8905672747951905,0.005176812076117423,0.7974789711276091,-0.10627094673633292,1.5315716196659703,0.3661616464083245,0.5273305006198339,0.3456433744169804,-1.3349373118137702,0.3043501904123781,0.6448869477951056,0.8349190753908383,-1.023405807478901,0.3865954317326442,0.07084055395748909,-0.2901087935675131,1.6444566286616846,0.5471155860670778,0.005176812076117423,0.005176812076117423,4.079616394254458,-0.31359071053648363,-0.08377571033449493,0.4272126540305929,2.1320329656479697,2.6987880108067723,1.071800525038966,0.5668228264787173,2.2757707336590367,2.34624122931555,0.28357365910325655,2.917749605386218,0.5273305006198339,-0.17439114903384173,0.5471155860670778,-0.6551091457204445,-0.31359071053648363,0.19958181332532843,-0.40868858056019347,3.104102422844003,0.7217588966997998,-0.31359071053648363,-0.4812782346091039,-1.1062863390031978,-0.4812782346091039,0.005176812076117423,0.8349190753908383,-0.6804737926663148,0.406945511095729,0.07084055395748909,0.8535361731217637,0.6834693746272135,-0.19731314994998111,-8.4659830013842,-1.7976755345030844,-1.9633114577538548,0.09253370913532158,-1.0508669815631295,0.28357365910325655,0.406945511095729,0.3456433744169804,-1.4237405696271823,1.7236380473068795,-0.24348703633272678,3.1769568474904344,-0.2667413189986047,3.482324846985818,0.11413110287400714,-0.38473594847995757,0.3043501904123781,-0.8093982448803362,1.3995215238872651,0.4675011541744141,0.22071433819033928,0.4675011541744141,1.3322253587909487,0.6254843056815558,-0.17439114903384173,0.17835812614782434,-0.17439114903384173,-0.19731314994998111,-0.36090298236806184,0.6448869477951056,-1.023405807478901,0.22071433819033928,0.24175657929060165,0.5074668730496471,0.19958181332532843 3430 Glycoside hydrolase superfamily [IPR017853] 6 16 2.5211038609406087 0.0116987316322343 O60502,P04062,P16278,Q9BTY2,P54802,P10253 Sequence InterPro Superfamily interpro_homologous_superfamily 223,68,38,361,124,349 223,68,2582,389,1336,3011,2164,1415,349,38,841,124,951,1907,361,1504 1.4328472746723286,2.993031551841918,-0.5302953342350691,0.816233531485841,0.04905067418434559,-0.8093982448803362,-0.31359071053648363,0.005176812076117423,0.9089823832894932,3.5165359909007803,0.32503982365867656,2.2187310778900433,0.2627094020641012,-0.19731314994998111,0.8905672747951905,-0.01690917370953021 3430 calmodulin-related 7 14 2.5139684779846383 0.0119381103738054 P80303,P41208,Q02818,Q14257,P0DP25,Q8IYU8,Q9BRK5 Functions Panther Protein class panther_protein_class 0,65,36,233,304,250,160 729,304,3076,2110,65,3183,0,36,233,2681,250,2275,317,160 0.406945511095729,1.0539628363107982,-0.8619817453617755,-0.2901087935675131,3.0302984430490625,-1.023405807478901,5.333361777399175,3.527894748469767,1.3995215238872651,-0.5798253703616462,1.2640484788395443,-0.36090298236806184,1.0181005541038732,1.8479240879335823 3430 Sphingolipid metabolism in senescence 6 13 2.490625595332524 0.0127518417215195 Q13510,P42345,P04062,P16278,Q06136,Q96G23 Processes and pathways WikiPathways msigdb_wp 158,354,68,38,87,61 441,68,1335,2945,596,38,2536,1419,1476,354,87,158,61 0.7217588966997998,2.993031551841918,0.04905067418434559,-0.7574012545226345,0.5273305006198339,3.5165359909007803,-0.5057234167351391,0.005176812076117423,-0.01690917370953021,0.8905672747951905,2.672453216244307,1.8479240879335823,3.104102422844003 3430 Regulation of mitochondrion organization 16 47 2.4900477377461905 0.0127725938290916 Q8N2A8,P42858,Q8NE86,Q9Y6C9,O14737,P30536,Q9H4A6,Q9UBN7,Q07812,P27544,P21796,Q9NUQ9,Q96A26,P12235,Q99536,O14965 Processes and pathways GO Biological process msigdb_gobp 132,259,425,167,329,12,268,439,368,239,20,314,88,182,316,467 1367,329,467,1467,1368,2208,2978,732,2784,488,2442,182,1630,20,239,3113,2215,12,1571,3019,259,1682,2009,368,2917,3259,1183,667,1973,1543,132,425,2959,88,2027,2483,3318,316,3190,268,2330,963,314,439,1878,2149,167 0.027163091494653614,0.9638324211451322,0.6834693746272135,-0.01690917370953021,0.027163091494653614,-0.3371883420413084,-0.7833273588538234,0.406945511095729,-0.6551091457204445,0.6642150900524303,-0.4569583228314796,1.6444566286616846,-0.08377571033449493,3.9859536481432736,1.3491309609547064,-0.9151668939436284,-0.3371883420413084,4.222429217331235,-0.061384384139230704,-0.8093982448803362,1.2296215579874639,-0.10627094673633292,-0.24348703633272678,0.8535361731217637,-0.7316181307528602,-1.1342490728645735,0.13563368348203628,0.4675011541744141,-0.22034471621492466,-0.03909589167063334,2.1610865858455655,0.7597604826477616,-0.7574012545226345,2.6592388401689844,-0.24348703633272678,-0.4569583228314796,-1.2766888241918128,1.0181005541038732,-1.023405807478901,1.1949644490190432,-0.38473594847995757,0.2627094020641012,1.036063009474167,0.7407953762815624,-0.17439114903384173,-0.2901087935675131,1.8016559746006866 3430 Autophagy 12 53 2.4833808102984327 0.0130141878426779 P54646,Q15382,Q9NS69,P42345,P13473,Q15388,O95613,Q13315,Q7Z3C6,Q9UBN7,P21796,Q8N4H5 Processes and pathways Reactome Pathways msigdb_reactome 254,290,3,354,196,355,423,332,459,439,20,29 1617,2099,3150,1413,423,2293,704,1161,1470,1023,2295,196,1630,20,354,1479,625,254,2716,1799,647,2061,1961,1530,1293,332,458,1383,794,768,290,355,881,459,1392,29,1446,2077,2027,3318,1452,1769,1597,1818,3121,3,1873,439,2286,3166,1883,2382,2203 -0.08377571033449493,-0.2901087935675131,-0.9689694457036316,0.005176812076117423,0.7597604826477616,-0.38473594847995757,0.4272126540305929,0.13563368348203628,-0.01690917370953021,0.22071433819033928,-0.38473594847995757,1.5640718300941014,-0.08377571033449493,3.9859536481432736,0.8905672747951905,-0.01690917370953021,0.5074668730496471,1.2468635762934643,-0.6047865559806115,-0.151577544698465,0.487523996503178,-0.2667413189986047,-0.22034471621492466,-0.03909589167063334,0.07084055395748909,0.9638324211451322,0.7026504351173741,0.027163091494653614,0.3661616464083245,0.3865954317326442,1.1249455781236504,0.8905672747951905,0.3043501904123781,0.7026504351173741,0.027163091494653614,3.706665868419647,0.005176812076117423,-0.2667413189986047,-0.24348703633272678,-1.2766888241918128,0.005176812076117423,-0.12887118746947637,-0.061384384139230704,-0.151577544698465,-0.9151668939436284,4.706308247813215,-0.17439114903384173,0.7407953762815624,-0.36090298236806184,-0.9689694457036316,-0.17439114903384173,-0.40868858056019347,-0.31359071053648363 3430 Abnormal csf protein level 8 13 2.475129829029988 0.0133187749735548 P15289,Q16625,P55011,P03886,Q9NR77,P07602,Q9NZJ7,P00403 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,322,394,74,297,77,243,213 1331,428,213,74,77,374,2668,3016,1958,394,322,297,243 0.04905067418434559,0.7407953762815624,1.4659622290827485,2.86699521405523,2.8157767839559593,0.8349190753908383,-0.5798253703616462,-0.8093982448803362,-0.22034471621492466,0.816233531485841,1.000074973722675,1.0895765601315317,1.3322253587909487 3430 FDA approved drug targets 36 125 2.4721006262833627 0.0134321701892938 P54646,Q13423,P55011,Q14534,Q16850,P38435,O95864,P20020,Q8N0U8,Q99720,P31939,Q16134,P42574,Q9UGN5,Q9UBN7,P49354,P00374,P49721,P12235,P23786,P21964,P04818,P03886,P14735,P28074,P12236,P49356,P10253,P05067,P42345,P49327,Q16836,P05141,P39023,P16615,Q07864 Functions Protein Atlas Protein class protein_atlas_protein_class 254,130,394,272,146,145,388,278,151,24,155,539,537,173,439,306,52,54,182,63,445,443,74,330,341,218,219,349,224,354,471,356,488,490,249,377 3148,1464,2099,1623,1624,1332,388,2581,52,2294,1517,1565,732,74,840,1890,2622,443,897,224,2744,488,2665,1335,3234,2864,2785,1090,1628,3401,3235,552,1162,349,1126,2625,2946,596,182,218,3014,2443,1742,3390,2444,1950,1128,330,2788,249,2536,278,597,1567,1475,3333,445,1839,2537,1049,63,1746,734,2445,3075,341,1476,2000,3376,3113,2866,943,155,985,1342,1287,145,490,3349,354,537,2752,1421,471,306,219,54,3256,1574,2753,1637,625,254,394,1530,3155,1902,1850,1295,2875,2460,377,130,1382,1647,1488,272,1907,1349,1699,539,1227,356,146,2268,151,2646,857,2849,24,777,1152,439,173,1325 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3430 FDA approved drug targets 36 125 2.4721006262833627 0.0134321701892938 P54646,Q13423,P55011,Q14534,Q16850,P38435,O95864,P20020,Q8N0U8,Q99720,P31939,Q16134,P42574,Q9UGN5,Q9UBN7,P49354,P00374,P49721,P12235,P23786,P21964,P04818,P03886,P14735,P28074,P12236,P49356,P10253,P05067,P42345,P49327,Q16836,P05141,P39023,P16615,Q07864 Drugs and Diseases Protein Atlas Disease involvement protein_atlas_disease_involvement 254,130,394,272,146,145,388,278,151,24,155,539,537,173,439,306,52,54,182,63,445,443,74,330,341,218,219,349,224,354,471,356,488,490,249,377 3148,1464,2099,1623,1624,1332,388,2581,52,2294,1517,1565,732,74,840,1890,2622,443,897,224,2744,488,2665,1335,3234,2864,2785,1090,1628,3401,3235,552,1162,349,1126,2625,2946,596,182,218,3014,2443,1742,3390,2444,1950,1128,330,2788,249,2536,278,597,1567,1475,3333,445,1839,2537,1049,63,1746,734,2445,3075,341,1476,2000,3376,3113,2866,943,155,985,1342,1287,145,490,3349,354,537,2752,1421,471,306,219,54,3256,1574,2753,1637,625,254,394,1530,3155,1902,1850,1295,2875,2460,377,130,1382,1647,1488,272,1907,1349,1699,539,1227,356,146,2268,151,2646,857,2849,24,777,1152,439,173,1325 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3430 Abnormal myocardium morphology 39 186 2.4698841206714426 0.0135156825976352 Q13423,Q9P032,Q96CU9,Q96IX5,Q9Y4P3,P14854,P06280,Q9H9S5,Q13426,Q14108,Q9P0J0,O43772,O43676,Q9H061,P21912,Q96RL7,P16278,P12235,O15360,Q86Y39,P47985,P23786,Q9NWS8,P04062,P13473,P03886,Q99959,P00403,P10253,Q16836,Q5XKP0,P49748,Q9BT22,Q9NPL8,Q99797,Q9NVI7,Q9NZ08,P54802,Q7KZN9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 130,399,263,396,269,392,389,411,21,22,149,152,25,26,282,292,38,182,308,188,191,63,194,68,196,74,333,213,349,356,357,232,371,372,384,385,386,124,257 812,1995,1086,1941,308,25,2975,1243,152,533,1467,2387,1206,3093,549,2438,2742,455,896,2903,2620,2783,3193,978,213,507,2978,74,840,68,3405,3181,389,938,2745,1415,3012,1246,733,1948,2786,349,182,196,1416,392,1792,642,1892,38,1212,787,2166,3048,1474,1418,282,1839,2395,2823,63,2054,3112,2503,3376,2866,2396,2543,841,3348,3129,1287,2168,1288,2546,2218,842,1573,1095,414,2450,2949,762,191,1421,471,232,3362,600,1574,1479,2400,686,124,2716,2912,2454,2507,3374,2718,3238,2872,820,1752,1690,2914,1295,951,2119,1253,130,21,2233,22,2065,3157,1855,1223,1350,905,356,2407,797,2177,713,357,257,1858,1971,188,2182,911,2184,1444,1714,3175,2071,1073,2188,2846,1231,263,396,292,856,3226,2522,2849,384,333,2609,3085,371,517,3177,887,2893,1149,26,2485,2771,1009,3001,2037,2526,411,2895,372,1116,385,194,2931,386,399,149,2378,2380,1609,1326,2096,2340,1362,269,1994,591,482 0.3456433744169804,-0.24348703633272678,0.17835812614782434,-0.22034471621492466,1.036063009474167,3.8372261164826145,-0.7833273588538234,0.09253370913532158,1.8937948621783494,0.6060065128039738,-0.01690917370953021,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.5864529093583782,-0.4569583228314796,-0.6298806123677426,0.7026504351173741,0.28357365910325655,-0.7316181307528602,-0.5549954789805401,-0.6551091457204445,-1.0508669815631295,0.24175657929060165,1.4659622290827485,0.6448869477951056,-0.7833273588538234,2.86699521405523,0.32503982365867656,2.993031551841918,-2.0313624559825123,-1.023405807478901,0.816233531485841,0.2627094020641012,-0.6298806123677426,0.005176812076117423,-0.8093982448803362,0.09253370913532158,0.406945511095729,-0.22034471621492466,-0.6551091457204445,0.9089823832894932,1.6444566286616846,1.5640718300941014,0.005176812076117423,0.816233531485841,-0.151577544698465,0.487523996503178,-0.19731314994998111,3.5165359909007803,0.11413110287400714,0.3661616464083245,-0.31359071053648363,-0.8356157493053581,-0.01690917370953021,0.005176812076117423,1.1425395010761892,-0.17439114903384173,-0.4327622425712757,-0.6804737926663148,3.0673208707632353,-0.2667413189986047,-0.9151668939436284,-0.4812782346091039,-1.5757554991734064,-0.7059762210511288,-0.4327622425712757,-0.5057234167351391,0.32503982365867656,-1.3643448569490237,-0.9419899846973533,0.07084055395748909,-0.31359071053648363,0.07084055395748909,-0.5057234167351391,-0.3371883420413084,0.32503982365867656,-0.061384384139230704,0.17835812614782434,0.7786548166059916,-0.4569583228314796,-0.7574012545226345,0.3865954317326442,1.5963727964305452,0.005176812076117423,0.6834693746272135,1.3995215238872651,-1.4537345413628453,0.5273305006198339,-0.061384384139230704,-0.01690917370953021,-0.4327622425712757,0.447397619113444,2.2187310778900433,-0.6047865559806115,-0.7316181307528602,-0.4569583228314796,-0.4812782346091039,-1.5449371974827035,-0.6047865559806115,-1.1062863390031978,-0.7059762210511288,0.3456433744169804,-0.12887118746947637,-0.10627094673633292,-0.7316181307528602,0.07084055395748909,0.2627094020641012,-0.2901087935675131,0.09253370913532158,2.1610865858455655,3.9859536481432736,-0.3371883420413084,3.9859536481432736,-0.2667413189986047,-0.9689694457036316,-0.17439114903384173,0.11413110287400714,0.04905067418434559,0.28357365910325655,0.8905672747951905,-0.4327622425712757,0.3661616464083245,-0.31359071053648363,0.4272126540305929,0.8905672747951905,1.2468635762934643,-0.17439114903384173,-0.22034471621492466,1.6124494198193353,-0.31359071053648363,0.28357365910325655,-0.31359071053648363,0.005176812076117423,-0.10627094673633292,-0.9961073484547495,-0.2667413189986047,0.19958181332532843,-0.31359071053648363,-0.6804737926663148,0.11413110287400714,1.2296215579874639,0.816233531485841,1.1249455781236504,0.32503982365867656,-1.0784930750204527,-0.4812782346091039,-0.6804737926663148,0.8349190753908383,0.9638324211451322,-0.5302953342350691,-0.8619817453617755,0.8535361731217637,0.6448869477951056,-0.9961073484547495,0.3043501904123781,-0.7059762210511288,0.15704238472925763,3.739581024322766,-0.4569583228314796,-0.6298806123677426,0.24175657929060165,-0.7833273588538234,-0.24348703633272678,-0.4812782346091039,0.7974789711276091,-0.7059762210511288,0.8535361731217637,0.17835812614782434,0.8349190753908383,1.5802470465011218,-0.7316181307528602,0.8349190753908383,0.816233531485841,1.9392759124745347,-0.40868858056019347,-0.40868858056019347,-0.061384384139230704,0.07084055395748909,-0.2667413189986047,-0.38473594847995757,0.04905067418434559,1.1949644490190432,-0.22034471621492466,0.5471155860670778,0.6834693746272135 3430 Metabolism of steroids 14 50 2.4687579083532727 0.0135582909854508 Q15392,O76062,P04062,Q15800,Q9Y6B6,Q53GQ0,Q14849,P30536,Q14534,Q16850,P38435,P48449,Q14739,P37268 Processes and pathways Reactome Pathways msigdb_reactome 2,164,68,101,300,202,43,12,272,146,145,184,311,123 3404,484,2434,678,468,164,2103,1208,561,68,1128,2788,1248,2538,2790,12,123,145,184,471,2302,3418,2673,2632,2799,1378,3156,3411,3132,272,311,43,3133,2725,2,990,1911,1259,101,146,202,993,998,2320,1315,1267,324,2034,438,300 -2.0313624559825123,0.6642150900524303,-0.4569583228314796,0.447397619113444,0.6834693746272135,1.8171233074337798,-0.2901087935675131,0.11413110287400714,0.5668228264787173,2.993031551841918,0.15704238472925763,-0.6551091457204445,0.09253370913532158,-0.5057234167351391,-0.6551091457204445,4.222429217331235,2.2187310778900433,2.0142315842992913,1.6444566286616846,0.6834693746272135,-0.38473594847995757,-2.614938713691235,-0.5798253703616462,-0.5549954789805401,-0.6551091457204445,0.027163091494653614,-0.9689694457036316,-2.2062494461722344,-0.9419899846973533,1.1775484830852023,1.036063009474167,3.413286496271575,-0.9419899846973533,-0.6047865559806115,4.706308247813215,0.24175657929060165,-0.19731314994998111,0.09253370913532158,2.5117605953310402,2.0142315842992913,1.5315716196659703,0.24175657929060165,0.24175657929060165,-0.38473594847995757,0.07084055395748909,0.09253370913532158,1.000074973722675,-0.24348703633272678,0.7407953762815624,1.0895765601315317 3430 vesicles 50 179 2.465077234932742 0.0136983720621932 Q15392,O95249,P53985,Q8IY95,Q13277,O75165,Q93050,Q01968,Q5HYI8,Q9Y5X3,Q9H2V7,P20020,Q8IZ07,P11279,O15400,O15127,Q9UM00,Q15904,Q9Y5X2,Q5VW38,Q8IXU6,Q8NF37,P48449,O96005,P49755,O95470,P61020,P13473,O15269,Q969V3,Q7Z3C6,P53367,P51798,Q8NBN3,Q9BTU6,Q06136,O00264,P30825,O75845,P42345,P11166,Q8IZA0,Q15907,Q15363,P50570,Q9Y5K8,O43808,O15173,O00767,O60476 Localization OpenCell Localization opencell_localization 2,258,509,654,260,506,136,649,265,270,148,278,669,413,532,163,558,434,573,48,179,568,184,181,315,64,447,196,441,461,459,209,335,212,480,87,216,225,468,354,595,237,111,241,491,639,486,117,484,621 216,2817,1367,814,1615,484,1275,930,1779,2158,163,2705,3293,117,816,441,3069,532,486,621,2343,932,1205,506,785,468,2103,2781,1125,258,1889,64,181,1677,732,684,897,2864,3217,3151,595,413,3236,196,2536,2746,1163,278,1024,1475,1248,1953,225,2542,2546,354,2299,1844,184,874,315,2009,1635,491,1685,335,209,1029,509,2359,2673,2796,3183,706,447,789,1346,1846,1059,2360,2798,1641,664,3317,2677,1531,649,87,1429,1298,260,2232,2175,768,1578,3158,2018,1434,241,2,990,1259,1699,434,111,1808,1104,265,48,2642,1970,1108,957,459,1262,714,179,654,669,2603,237,1071,853,2241,212,568,829,1446,1447,1313,136,1000,461,1922,1231,3206,1865,1232,2193,2483,2693,1453,1233,480,1717,746,1457,1268,1320,1009,148,3121,1820,1871,1151,3415,1875,2426,1876,1989,1360,1825,2491,3086,2286,2737,558,1014,3165,2288,1121,3166,1828,1122,3088,639,573,270,811 1.4494309133701686,-0.6804737926663148,0.027163091494653614,0.3456433744169804,-0.08377571033449493,0.6642150900524303,0.07084055395748909,0.2627094020641012,-0.151577544698465,-0.31359071053648363,1.8171233074337798,-0.6047865559806115,-1.2191778402877913,2.2757707336590367,0.3456433744169804,0.7217588966997998,-0.8619817453617755,0.6060065128039738,0.6642150900524303,0.5074668730496471,-0.40868858056019347,0.2627094020641012,0.11413110287400714,0.6448869477951056,0.3661616464083245,0.6834693746272135,-0.2901087935675131,-0.6551091457204445,0.15704238472925763,1.2296215579874639,-0.19731314994998111,3.0426662360183325,1.6444566286616846,-0.10627094673633292,0.406945511095729,0.447397619113444,0.28357365910325655,-0.7059762210511288,-1.0784930750204527,-0.9689694457036316,0.5273305006198339,0.7786548166059916,-1.1062863390031978,1.5640718300941014,-0.5057234167351391,-0.6298806123677426,0.13563368348203628,1.1600736506845353,0.22071433819033928,-0.01690917370953021,0.09253370913532158,-0.22034471621492466,1.4328472746723286,-0.5057234167351391,-0.5057234167351391,0.8905672747951905,-0.38473594847995757,-0.17439114903384173,1.6444566286616846,0.3043501904123781,1.0181005541038732,-0.24348703633272678,-0.08377571033449493,0.6642150900524303,-0.10627094673633292,0.945614424806558,1.4988693711510455,0.22071433819033928,0.6448869477951056,-0.40868858056019347,-0.5798253703616462,-0.6551091457204445,-1.023405807478901,0.4272126540305929,0.7217588966997998,0.3661616464083245,0.04905067418434559,-0.17439114903384173,0.19958181332532843,-0.40868858056019347,-0.6551091457204445,-0.08377571033449493,0.4675011541744141,-1.2766888241918128,-0.5798253703616462,-0.03909589167063334,0.487523996503178,2.672453216244307,0.005176812076117423,0.07084055395748909,1.2296215579874639,-0.3371883420413084,-0.31359071053648363,0.3865954317326442,-0.061384384139230704,-0.9689694457036316,-0.24348703633272678,0.005176812076117423,1.3491309609547064,4.706308247813215,0.24175657929060165,0.09253370913532158,-0.10627094673633292,0.7407953762815624,2.34624122931555,-0.151577544698465,0.17835812614782434,1.2123219939175685,3.3551136813137883,-0.5549954789805401,-0.22034471621492466,0.17835812614782434,0.2627094020641012,0.7026504351173741,0.09253370913532158,0.4272126540305929,1.6603878760836814,0.487523996503178,0.4675011541744141,-0.5302953342350691,1.382778649014379,0.19958181332532843,0.32503982365867656,-0.3371883420413084,1.482441592729086,0.5668228264787173,0.3456433744169804,0.005176812076117423,0.005176812076117423,0.07084055395748909,2.1174474931929272,0.24175657929060165,0.7026504351173741,-0.19731314994998111,0.11413110287400714,-1.0508669815631295,-0.17439114903384173,0.11413110287400714,-0.31359071053648363,-0.4569583228314796,-0.5798253703616462,0.005176812076117423,0.11413110287400714,0.6834693746272135,-0.10627094673633292,0.406945511095729,0.005176812076117423,0.09253370913532158,0.07084055395748909,0.24175657929060165,1.9392759124745347,-0.9151668939436284,-0.151577544698465,-0.17439114903384173,0.15704238472925763,-2.4625446972431617,-0.17439114903384173,-0.4327622425712757,-0.17439114903384173,-0.22034471621492466,0.04905067418434559,-0.151577544698465,-0.4569583228314796,-0.8619817453617755,-0.36090298236806184,-0.6047865559806115,0.5864529093583782,0.24175657929060165,-0.9689694457036316,-0.36090298236806184,0.17835812614782434,-0.9689694457036316,-0.151577544698465,0.17835812614782434,-0.8619817453617755,0.5074668730496471,0.5668228264787173,1.1949644490190432,0.3661616464083245 3430 Steroid metabolism 9 28 2.463620360790597 0.0137541707313124 P54646,Q15392,O15118,O76062,P04062,Q15800,Q06520,Q16850,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 254,2,98,164,68,101,174,146,123 98,1785,468,164,2977,1677,68,1128,2790,985,123,3418,254,1482,2062,3156,174,3132,311,2725,2,1259,101,146,2849,438,2339,1119 2.5388692262913795,-0.151577544698465,0.6834693746272135,1.8171233074337798,-0.7833273588538234,-0.10627094673633292,2.993031551841918,0.15704238472925763,-0.6551091457204445,0.24175657929060165,2.2187310778900433,-2.614938713691235,1.2468635762934643,-0.01690917370953021,-0.2667413189986047,-0.9689694457036316,1.7078960893112645,-0.9419899846973533,1.036063009474167,-0.6047865559806115,4.706308247813215,0.09253370913532158,2.5117605953310402,2.0142315842992913,-0.6804737926663148,0.7407953762815624,-0.38473594847995757,0.17835812614782434 3430 Golgi associated vesicle 7 33 2.4591904145989893 0.0139250739218419 Q8N511,P05067,Q9Y3B3,P24390,Q9Y287,Q15363,O43731 Localization GO Cellular component msigdb_gocc 32,224,133,4,166,241,59 1275,59,1465,1676,224,3217,3151,2210,4,1341,2299,1250,315,3153,2114,1029,2871,1346,1641,1531,649,241,32,2129,2132,2029,3176,633,427,1360,166,133,811 0.07084055395748909,3.104102422844003,-0.01690917370953021,-0.10627094673633292,1.4328472746723286,-1.0784930750204527,-0.9689694457036316,-0.3371883420413084,4.687680585731818,0.04905067418434559,-0.38473594847995757,0.09253370913532158,1.0181005541038732,-0.9689694457036316,-0.2901087935675131,0.22071433819033928,-0.7059762210511288,0.04905067418434559,-0.08377571033449493,-0.03909589167063334,0.487523996503178,1.3491309609547064,3.6735633983186133,-0.2901087935675131,-0.2901087935675131,-0.24348703633272678,-0.9961073484547495,0.5074668730496471,0.7597604826477616,0.04905067418434559,1.8016559746006866,2.1610865858455655,0.3661616464083245 3430 Oxidative phosphorylation 15 61 2.446611848884541 0.0144206045919825 O75964,Q7KZN9,Q93050,P14406,P03886,P22695,Q9UDW1,P13073,O14949,P00403,P24539,O43676,Q86Y39,Q9Y487,P47985 Processes and pathways KEGG Pathways msigdb_kegg 33,257,136,9,74,106,92,178,82,213,183,25,188,94,191 1086,1941,82,25,2975,2387,1206,3093,681,2438,3268,33,839,3215,2620,978,213,74,536,1245,2666,1739,178,9,392,3127,3128,3048,2296,1475,3333,282,106,183,2214,3112,2866,1051,2001,1094,2546,191,3255,3362,492,2588,446,2360,3363,434,2837,905,257,188,136,3001,92,2491,94,639,482 0.17835812614782434,-0.22034471621492466,2.7380578010529537,3.8372261164826145,-0.7833273588538234,-0.4327622425712757,0.11413110287400714,-0.8884981438055674,0.447397619113444,-0.4569583228314796,-1.1623836255706177,3.5731076371518076,0.32503982365867656,-1.0784930750204527,-0.5549954789805401,0.24175657929060165,1.4659622290827485,2.86699521405523,0.6060065128039738,0.09253370913532158,-0.5798253703616462,-0.12887118746947637,1.6603878760836814,4.459556787416143,0.816233531485841,-0.9419899846973533,-0.9419899846973533,-0.8356157493053581,-0.38473594847995757,-0.01690917370953021,-1.3349373118137702,1.1425395010761892,2.4019708945127647,1.6444566286616846,-0.3371883420413084,-0.9151668939436284,-0.7059762210511288,0.19958181332532843,-0.24348703633272678,0.17835812614782434,-0.5057234167351391,1.5963727964305452,-1.1342490728645735,-1.4537345413628453,0.6642150900524303,-0.5302953342350691,0.7217588966997998,-0.40868858056019347,-1.4537345413628453,0.7407953762815624,-0.6804737926663148,0.28357365910325655,1.2468635762934643,1.6124494198193353,2.1174474931929272,-0.7833273588538234,2.6194057651180533,-0.4569583228314796,2.6060641851362782,0.5074668730496471,0.6834693746272135 3430 Intrinsic component of plasma membrane 27 78 2.446048665507451 0.0144431503771713 P35613,P53985,P01889,P55011,Q8NAN2,Q9UIQ6,O95864,P20020,O60637,P11279,Q15043,O76062,O15031,P0DP25,O43657,O96005,P12235,Q8WTV0,Q9BTU6,O00264,P30825,P05067,O15118,Q12907,Q99797,P05141,P16615 Localization GO Cellular component msigdb_gocc 375,509,507,394,142,143,388,278,27,413,415,164,169,304,51,181,182,71,480,216,225,224,98,495,384,488,249 1241,216,815,3278,3148,169,2097,98,727,51,27,164,388,181,507,732,684,897,224,488,2665,3234,304,1210,1338,595,413,2210,182,249,3253,278,1567,1840,1049,705,225,1955,375,2545,1376,509,2170,394,1216,1690,739,1691,2266,495,1964,526,1909,415,1064,1699,2067,1393,1443,142,1588,71,717,384,2963,1502,1401,480,3427,1150,2250,964,2335,1602,143,967,1121,1611 0.09253370913532158,1.4494309133701686,0.3456433744169804,-1.1906923971648218,-0.9689694457036316,1.7705859554975645,-0.2901087935675131,2.5388692262913795,0.406945511095729,3.2607896593204937,3.728629970858737,1.8171233074337798,0.816233531485841,1.6444566286616846,0.6448869477951056,0.406945511095729,0.447397619113444,0.28357365910325655,1.4328472746723286,0.6642150900524303,-0.5798253703616462,-1.1062863390031978,1.0539628363107982,0.11413110287400714,0.04905067418434559,0.5273305006198339,0.7786548166059916,-0.3371883420413084,1.6444566286616846,1.2640484788395443,-1.1342490728645735,1.1600736506845353,-0.061384384139230704,-0.17439114903384173,0.19958181332532843,0.4272126540305929,1.4328472746723286,-0.22034471621492466,0.8349190753908383,-0.5057234167351391,0.027163091494653614,0.6448869477951056,-0.31359071053648363,0.816233531485841,0.11413110287400714,-0.10627094673633292,0.406945511095729,-0.10627094673633292,-0.36090298236806184,0.6642150900524303,-0.22034471621492466,0.6254843056815558,-0.19731314994998111,0.7786548166059916,0.19958181332532843,-0.10627094673633292,-0.2667413189986047,0.027163091494653614,0.005176812076117423,2.0290981867058675,-0.061384384139230704,2.917749605386218,0.4272126540305929,0.8349190753908383,-0.7574012545226345,-0.01690917370953021,0.027163091494653614,0.6834693746272135,-8.4659830013842,0.15704238472925763,-0.3371883420413084,0.2627094020641012,-0.38473594847995757,-0.061384384139230704,2.0290981867058675,0.2627094020641012,0.17835812614782434,-0.061384384139230704 3430 EF-hand domain pair [IPR011992] 15 57 2.44203579337103 0.0146046985338625 P80303,Q9NWM8,P41208,Q02818,O75071,Q14257,Q8IYU8,Q96AY3,P0DP25,O95302,Q9H223,O95202,Q99584,Q9Y680,Q9BRK5 Sequence InterPro Superfamily interpro_homologous_superfamily 0,325,65,36,90,233,250,366,304,147,313,154,317,95,160 1996,729,90,1674,1369,154,147,2863,2390,304,2444,3414,2212,1247,3280,2667,3196,3076,2110,3348,65,2793,2003,1374,1686,3183,0,36,1963,1696,233,3026,2681,379,1182,2183,1973,1543,250,1976,568,1186,366,2275,1448,317,160,313,1505,1819,325,2426,1013,3412,967,1198,95 -0.24348703633272678,0.406945511095729,2.6194057651180533,-0.10627094673633292,0.027163091494653614,1.8785482781004688,1.9843746291639714,-0.7059762210511288,-0.4327622425712757,1.0539628363107982,-0.4569583228314796,-2.314462314047482,-0.3371883420413084,0.09253370913532158,-1.1906923971648218,-0.5798253703616462,-1.0508669815631295,-0.8619817453617755,-0.2901087935675131,-1.3643448569490237,3.0302984430490625,-0.6551091457204445,-0.24348703633272678,0.027163091494653614,-0.10627094673633292,-1.023405807478901,5.333361777399175,3.527894748469767,-0.22034471621492466,-0.10627094673633292,1.3995215238872651,-0.8093982448803362,-0.5798253703616462,0.8349190753908383,0.13563368348203628,-0.31359071053648363,-0.22034471621492466,-0.03909589167063334,1.2640484788395443,-0.22034471621492466,0.5668228264787173,0.13563368348203628,0.872085387655934,-0.36090298236806184,0.005176812076117423,1.0181005541038732,1.8479240879335823,1.036063009474167,-0.01690917370953021,-0.151577544698465,1.000074973722675,-0.4327622425712757,0.24175657929060165,-2.2062494461722344,0.2627094020641012,0.13563368348203628,2.592690371019141 3430 Progressive neurologic deterioration 10 21 2.441656450360873 0.0146200520309511 P15289,P04062,Q5XKP0,P16278,Q9Y287,P07602,Q9NZJ7,Q9NPL8,P54802,P21912 Drugs and Diseases Human Phenotype Ontology msigdb_hp 374,68,357,38,166,77,243,372,124,282 428,68,77,3011,374,38,2668,282,2866,2450,124,1423,2716,1298,2834,357,2919,2849,372,243,166 0.7407953762815624,2.993031551841918,2.8157767839559593,-0.8093982448803362,0.8349190753908383,3.5165359909007803,-0.5798253703616462,1.1425395010761892,-0.7059762210511288,-0.4569583228314796,2.2187310778900433,0.005176812076117423,-0.6047865559806115,0.07084055395748909,-0.6804737926663148,0.8905672747951905,-0.7316181307528602,-0.6804737926663148,0.8535361731217637,1.3322253587909487,1.8016559746006866 3430 Metapathway biotransformation phase i and ii 7 25 2.440627205856488 0.0146617812873448 P78417,Q86UY6,Q06520,Q16850,P07099,Q6UW02,O15217 Processes and pathways WikiPathways msigdb_wp 103,109,174,146,18,115,118 1088,118,3092,422,2294,18,2348,2788,2789,445,2710,3315,2752,2753,103,174,146,115,175,109,2243,744,1553,2247,2151 0.17835812614782434,2.2757707336590367,-0.8884981438055674,0.7597604826477616,-0.38473594847995757,4.048560352725201,-0.40868858056019347,-0.6551091457204445,-0.6551091457204445,0.7217588966997998,-0.6047865559806115,-1.2766888241918128,-0.6298806123677426,-0.6298806123677426,2.4708459283490147,1.7078960893112645,2.0142315842992913,2.3322196827838484,1.692107285757572,2.3880915476469537,-0.3371883420413084,0.406945511095729,-0.03909589167063334,-0.3371883420413084,-0.2901087935675131 3430 Cellular homeostasis 51 150 2.436092939478109 0.0148468693160301 P54646,P42858,Q9NUT2,Q15120,Q93050,Q9HD20,P55011,Q07820,P09601,P20020,O95202,O14617,P06576,Q8N511,Q15043,O43819,Q9UM00,Q8NE86,Q15904,P0DP25,P32119,P50897,Q9BWH2,Q6YHU6,Q96A33,P09429,P13473,P14735,Q00535,Q9P2D1,Q4KMQ2,Q8N5M9,Q9H1E3,O76024,Q16763,Q9Y6M7,Q9Y487,P10253,P05067,P78417,P52789,O00203,Q15907,Q07812,Q9UJZ1,O75503,Q92544,O75027,P16615,Q8IYU8,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 254,259,398,652,136,137,394,525,17,278,154,659,536,32,415,533,558,425,434,304,305,53,454,586,323,444,196,330,582,339,608,210,211,455,476,619,94,349,224,103,236,483,111,368,520,116,629,623,249,250,127 2043,483,1366,1615,2739,659,533,2437,1205,623,116,935,3321,455,154,1889,2498,937,3193,2294,732,840,3009,897,224,1335,536,3234,3011,3372,1469,444,17,1948,2049,304,349,2443,196,2211,3182,330,249,1247,2536,1793,2746,2667,2393,278,940,1248,1049,2445,1520,3395,2710,1476,2167,2000,1631,3076,305,2546,259,1682,2006,53,1685,2057,1376,3154,236,901,254,2170,394,3237,1896,2360,1031,2550,2635,103,3155,582,1296,368,525,3396,1300,1802,989,3240,1649,415,652,1064,434,111,476,2267,2268,666,608,586,2024,1109,1393,3383,1973,1543,250,911,32,210,425,1352,629,136,323,1231,2371,2997,3176,1594,856,2135,1817,2963,2733,454,1006,211,1982,137,127,398,2614,339,1933,2491,520,558,1016,3211,94,2155,3330,619 -0.2667413189986047,0.6642150900524303,0.027163091494653614,-0.08377571033449493,-0.6298806123677426,0.4675011541744141,0.6060065128039738,-0.4569583228314796,0.11413110287400714,0.5074668730496471,2.3181620708424706,0.2627094020641012,-1.3057195477388794,0.7026504351173741,1.8785482781004688,-0.19731314994998111,-0.4812782346091039,0.2627094020641012,-1.0508669815631295,-0.38473594847995757,0.406945511095729,0.32503982365867656,-0.8093982448803362,0.28357365910325655,1.4328472746723286,0.04905067418434559,0.6060065128039738,-1.1062863390031978,-0.8093982448803362,-1.5143297421023834,-0.01690917370953021,0.7217588966997998,4.05893051652828,-0.22034471621492466,-0.2667413189986047,1.0539628363107982,0.9089823832894932,-0.4569583228314796,1.5640718300941014,-0.3371883420413084,-1.023405807478901,0.9638324211451322,1.2640484788395443,0.09253370913532158,-0.5057234167351391,-0.151577544698465,-0.6298806123677426,-0.5798253703616462,-0.4327622425712757,1.1600736506845353,0.2627094020641012,0.09253370913532158,0.19958181332532843,-0.4569583228314796,-0.03909589167063334,-1.7012045060061012,-0.6047865559806115,-0.01690917370953021,-0.31359071053648363,-0.24348703633272678,-0.08377571033449493,-0.8619817453617755,1.0539628363107982,-0.5057234167351391,1.2296215579874639,-0.10627094673633292,-0.24348703633272678,3.2250123758744826,-0.10627094673633292,-0.2667413189986047,0.027163091494653614,-0.9689694457036316,1.382778649014379,0.28357365910325655,1.2468635762934643,-0.31359071053648363,0.816233531485841,-1.1062863390031978,-0.19731314994998111,-0.40868858056019347,0.22071433819033928,-0.5057234167351391,-0.5549954789805401,2.4708459283490147,-0.9689694457036316,0.5471155860670778,0.07084055395748909,0.8535361731217637,0.6254843056815558,-1.7012045060061012,0.07084055395748909,-0.151577544698465,0.24175657929060165,-1.1062863390031978,-0.08377571033449493,0.7786548166059916,0.487523996503178,0.19958181332532843,0.7407953762815624,2.34624122931555,0.6834693746272135,-0.36090298236806184,-0.36090298236806184,0.4675011541744141,0.5273305006198339,0.5471155860670778,-0.24348703633272678,0.17835812614782434,0.027163091494653614,-1.6067879521771078,-0.22034471621492466,-0.03909589167063334,1.2640484788395443,0.28357365910325655,3.6735633983186133,1.4988693711510455,0.7597604826477616,0.04905067418434559,0.5074668730496471,2.1174474931929272,1.000074973722675,0.11413110287400714,-0.40868858056019347,-0.7833273588538234,-0.9961073484547495,-0.061384384139230704,0.32503982365867656,-0.2901087935675131,-0.151577544698465,-0.7574012545226345,-0.6047865559806115,0.7217588966997998,0.24175657929060165,1.4988693711510455,-0.22034471621492466,2.1028225946561765,2.1899853400179143,0.816233531485841,-0.5302953342350691,0.945614424806558,-0.19731314994998111,-0.4569583228314796,0.6448869477951056,0.5864529093583782,0.24175657929060165,-1.0508669815631295,2.6060641851362782,-0.2901087935675131,-1.3057195477388794,0.5273305006198339 3430 Lipid transport 6 24 2.4276930211214007 0.0151951987307188 O15118,Q14849,Q9BQE5,Q9BUR5,Q9H2V7,Q99720 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 98,43,15,275,148,24 1241,2739,98,3008,1248,2538,1482,2062,43,608,3187,3329,1315,24,15,2524,275,1717,324,746,2034,148,1877,1934 0.09253370913532158,-0.6298806123677426,2.5388692262913795,-0.8093982448803362,0.09253370913532158,-0.5057234167351391,-0.01690917370953021,-0.2667413189986047,3.413286496271575,0.5273305006198339,-1.023405807478901,-1.3057195477388794,0.07084055395748909,3.8907768973797325,4.131016779152228,-0.4812782346091039,1.1775484830852023,-0.10627094673633292,1.000074973722675,0.406945511095729,-0.24348703633272678,1.9392759124745347,-0.17439114903384173,-0.19731314994998111 3430 Exopeptidase activity 7 32 2.4272875642293603 0.0152121928724411 P55786,O14773,P42785,Q9H3G5,O75844,P10619,Q9HB40 Functions GO Molecular function msigdb_gomf 128,110,47,49,81,113,55 110,81,936,732,1337,113,3097,3298,1954,2545,47,2828,128,3336,402,1914,909,2127,615,461,1355,804,3319,49,2248,55,3106,2613,2090,386,143,892 2.360226918485896,2.7510864124399865,0.2627094020641012,0.406945511095729,0.04905067418434559,2.3322196827838484,-0.8884981438055674,-1.2191778402877913,-0.22034471621492466,-0.5057234167351391,3.3551136813137883,-0.6804737926663148,2.1755552047661753,-1.3349373118137702,0.7974789711276091,-0.19731314994998111,0.28357365910325655,-0.2901087935675131,0.5273305006198339,0.7026504351173741,0.04905067418434559,0.3661616464083245,-1.2766888241918128,3.3551136813137883,-0.3371883420413084,3.1769568474904344,-0.8884981438055674,-0.5302953342350691,-0.2667413189986047,0.8349190753908383,2.0290981867058675,0.3043501904123781 3430 Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 14 34 2.4219530265395206 0.0154373458671759 P30519,Q9NVH6,Q15800,O95864,Q16850,P09601,Q14534,P13674,O00767,Q6UW02,P16435,O75592,O75845,Q6P6C2 Functions GO Molecular function msigdb_gomf 1,657,101,388,146,17,272,641,484,115,310,624,468,627 2818,484,1124,2661,1204,2290,624,468,388,1790,17,641,310,2824,1,2303,2551,3098,272,101,146,880,1439,627,115,1441,1583,994,2367,691,921,1149,657,3146 -0.6804737926663148,0.6642150900524303,0.15704238472925763,-0.5798253703616462,0.11413110287400714,-0.38473594847995757,0.5074668730496471,0.6834693746272135,0.816233531485841,-0.151577544698465,4.05893051652828,0.487523996503178,1.036063009474167,-0.6804737926663148,5.005721299000376,-0.38473594847995757,-0.5057234167351391,-0.8884981438055674,1.1775484830852023,2.5117605953310402,2.0142315842992913,0.3043501904123781,0.005176812076117423,0.5074668730496471,2.3322196827838484,0.005176812076117423,-0.061384384139230704,0.24175657929060165,-0.40868858056019347,0.447397619113444,0.28357365910325655,0.15704238472925763,0.487523996503178,-0.9419899846973533 3430 Endomembrane system organization 47 174 2.419021617447761 0.0155623153355117 Q9Y3B3,P42858,Q13277,O75165,Q86XL3,Q2M389,Q9H4A6,Q14108,Q8TBA6,Q8NHH9,O75955,Q15041,Q9BVK6,O95197,Q13190,Q96GC9,P43034,O43681,P49755,Q96A33,Q8IXJ6,P61020,Q8NFQ8,Q9H5V9,O15260,P06493,Q7Z3C6,O94901,Q4KMQ2,O75844,Q8N5M9,Q9BTU6,P48729,Q7L5D6,Q15629,Q9UQB8,Q14789,P57088,P16615,Q9P2W9,Q12907,Q15363,P50570,P46379,Q9NPA0,Q9BTV4,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 133,259,260,506,140,527,268,22,286,416,534,424,427,42,301,569,564,428,315,323,587,447,193,590,319,577,459,574,608,81,210,480,342,478,89,93,605,493,249,107,495,241,491,121,519,517,127 1241,3214,1367,1202,659,2740,975,930,1779,2158,319,3070,428,1514,2343,1784,1736,506,2160,785,3313,3180,81,534,574,2781,42,1889,2498,2978,1335,577,3372,249,2536,2908,2668,1248,2445,1476,1477,1287,1748,2218,259,564,121,2505,342,874,315,600,1479,491,1685,987,2359,493,1845,706,447,789,2012,664,1899,903,1752,1576,1532,1295,2460,1430,1643,495,1645,2985,301,260,22,2558,989,605,3282,424,710,3158,1698,241,89,527,608,1702,1703,2882,3274,881,478,957,459,1859,667,140,2365,587,1497,1585,1394,210,2242,3387,1395,193,416,2644,286,2318,1446,1447,3119,3140,2844,1313,323,569,1036,1769,2323,1502,1005,2524,480,517,427,1457,2034,1008,1009,268,590,923,2325,3121,1871,519,127,1875,1041,3005,1195,1876,1989,107,1406,1934,3039,2286,2615,2150,2737,3007,2288,2200,2700,969,93,1361,1199,2935,1828,1082,133,2341,2384,1328 0.09253370913532158,-1.0784930750204527,0.027163091494653614,0.11413110287400714,0.4675011541744141,-0.6298806123677426,0.24175657929060165,0.2627094020641012,-0.151577544698465,-0.31359071053648363,1.000074973722675,-0.8619817453617755,0.7407953762815624,-0.03909589167063334,-0.40868858056019347,-0.151577544698465,-0.12887118746947637,0.6448869477951056,-0.31359071053648363,0.3661616464083245,-1.2766888241918128,-1.023405807478901,2.7510864124399865,0.6060065128039738,0.5471155860670778,-0.6551091457204445,3.4479092742401036,-0.19731314994998111,-0.4812782346091039,-0.7833273588538234,0.04905067418434559,0.5471155860670778,-1.5143297421023834,1.2640484788395443,-0.5057234167351391,-0.7316181307528602,-0.5798253703616462,0.09253370913532158,-0.4569583228314796,-0.01690917370953021,-0.01690917370953021,0.07084055395748909,-0.12887118746947637,-0.3371883420413084,1.2296215579874639,0.5668228264787173,2.247325615021821,-0.4812782346091039,0.9273312549578325,0.3043501904123781,1.0181005541038732,0.5273305006198339,-0.01690917370953021,0.6642150900524303,-0.10627094673633292,0.24175657929060165,-0.40868858056019347,0.6642150900524303,-0.17439114903384173,0.4272126540305929,0.7217588966997998,0.3661616464083245,-0.24348703633272678,0.4675011541744141,-0.19731314994998111,0.28357365910325655,-0.12887118746947637,-0.061384384139230704,-0.03909589167063334,0.07084055395748909,-0.4569583228314796,0.005176812076117423,-0.08377571033449493,0.6642150900524303,-0.08377571033449493,-0.7833273588538234,1.071800525038966,1.2296215579874639,3.9859536481432736,-0.5057234167351391,0.24175657929060165,0.5273305006198339,-1.1906923971648218,0.7597604826477616,0.4272126540305929,-0.9689694457036316,-0.10627094673633292,1.3491309609547064,2.632715285689517,0.6254843056815558,0.5273305006198339,-0.10627094673633292,-0.10627094673633292,-0.7059762210511288,-1.1623836255706177,0.3043501904123781,0.6834693746272135,0.2627094020641012,0.7026504351173741,-0.17439114903384173,0.4675011541744141,2.073453552149814,-0.40868858056019347,0.5471155860670778,-0.01690917370953021,-0.061384384139230704,0.027163091494653614,1.4988693711510455,-0.3371883420413084,-1.638037942852283,0.027163091494653614,1.5963727964305452,0.7786548166059916,-0.5549954789805401,1.1425395010761892,-0.38473594847995757,0.005176812076117423,0.005176812076117423,-0.9151668939436284,-0.9419899846973533,-0.6804737926663148,0.07084055395748909,1.000074973722675,0.5668228264787173,0.22071433819033928,-0.12887118746947637,-0.38473594847995757,-0.01690917370953021,0.24175657929060165,-0.4812782346091039,0.6834693746272135,0.6448869477951056,0.7597604826477616,0.005176812076117423,-0.24348703633272678,0.24175657929060165,0.24175657929060165,1.1949644490190432,0.5471155860670778,0.28357365910325655,-0.38473594847995757,-0.9151668939436284,-0.17439114903384173,0.6448869477951056,2.1899853400179143,-0.17439114903384173,0.22071433819033928,-0.7833273588538234,0.13563368348203628,-0.17439114903384173,-0.22034471621492466,2.4019708945127647,0.027163091494653614,-0.19731314994998111,-0.8093982448803362,-0.36090298236806184,-0.5302953342350691,-0.2901087935675131,-0.6047865559806115,-0.7833273588538234,-0.36090298236806184,-0.31359071053648363,-0.5798253703616462,0.2627094020641012,2.6060641851362782,0.04905067418434559,0.13563368348203628,-0.7316181307528602,-0.151577544698465,0.19958181332532843,2.1610865858455655,-0.38473594847995757,-0.40868858056019347,0.07084055395748909 3430 EF-Hand 1, calcium-binding site [IPR018247] 11 41 2.4181380286782743 0.0156001579708635 P80303,Q9NWM8,P41208,Q02818,Q14257,P0DP25,O95302,Q9H223,O95202,Q9Y680,Q9BRK5 Sequence InterPro Binding site interpro_binding_site 0,325,65,36,233,304,147,313,154,95,160 1996,729,1674,1369,154,147,2863,2390,304,2444,3414,2212,3280,2667,3076,2110,65,2793,2003,0,36,1963,1696,233,3026,2681,1182,1973,1543,1186,366,1448,160,313,1505,325,2426,1013,3412,1198,95 -0.24348703633272678,0.406945511095729,-0.10627094673633292,0.027163091494653614,1.8785482781004688,1.9843746291639714,-0.7059762210511288,-0.4327622425712757,1.0539628363107982,-0.4569583228314796,-2.314462314047482,-0.3371883420413084,-1.1906923971648218,-0.5798253703616462,-0.8619817453617755,-0.2901087935675131,3.0302984430490625,-0.6551091457204445,-0.24348703633272678,5.333361777399175,3.527894748469767,-0.22034471621492466,-0.10627094673633292,1.3995215238872651,-0.8093982448803362,-0.5798253703616462,0.13563368348203628,-0.22034471621492466,-0.03909589167063334,0.13563368348203628,0.872085387655934,0.005176812076117423,1.8479240879335823,1.036063009474167,-0.01690917370953021,1.000074973722675,-0.4327622425712757,0.24175657929060165,-2.2062494461722344,0.13563368348203628,2.592690371019141 3430 Abnormal aortic valve morphology 11 43 2.416758829427047 0.0156593886084446 P04062,Q9UHX1,Q96L58,Q9Y4P3,P06280,Q9P2D1,O75844,P51812,Q6PGP7,O15360,P37268 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,6,234,269,389,339,81,19,307,308,123 2937,2776,308,3149,1243,1833,81,507,2978,68,389,3219,445,3196,2217,2543,1287,123,1288,19,2673,1640,1847,1689,2872,1532,1856,1223,1807,1306,1182,307,2320,2074,234,887,2895,1116,339,6,2378,1991,269 -0.7574012545226345,-0.6551091457204445,1.036063009474167,-0.9689694457036316,0.09253370913532158,-0.17439114903384173,2.7510864124399865,0.6448869477951056,-0.7833273588538234,2.993031551841918,0.816233531485841,-1.0784930750204527,0.7217588966997998,-1.0508669815631295,-0.3371883420413084,-0.5057234167351391,0.07084055395748909,2.2187310778900433,0.07084055395748909,4.027765214582355,-0.5798253703616462,-0.08377571033449493,-0.17439114903384173,-0.10627094673633292,-0.7059762210511288,-0.03909589167063334,-0.17439114903384173,0.11413110287400714,-0.151577544698465,0.07084055395748909,0.13563368348203628,1.0539628363107982,-0.38473594847995757,-0.2667413189986047,1.3995215238872651,0.3043501904123781,-0.7059762210511288,0.17835812614782434,0.945614424806558,4.612592293772992,-0.40868858056019347,-0.22034471621492466,1.1949644490190432 3430 Lipid homeostasis 10 27 2.416334218402225 0.0156776636018853 P54646,Q15067,O15118,O15260,Q9Y6C9,Q9Y6B6,Q8WTV0,P28340,Q9NQC3,Q5BJF2 Processes and pathways GO Biological process msigdb_gobp 254,350,98,319,167,300,71,240,127,31 1944,98,680,319,1208,1743,240,3315,985,1343,254,1482,3411,350,31,881,586,71,2371,454,1505,2086,127,2339,2699,300,167 -0.22034471621492466,2.5388692262913795,0.447397619113444,1.000074973722675,0.11413110287400714,-0.12887118746947637,1.3491309609547064,-1.2766888241918128,0.24175657929060165,0.04905067418434559,1.2468635762934643,-0.01690917370953021,-2.2062494461722344,0.9089823832894932,3.6735633983186133,0.3043501904123781,0.5471155860670778,2.917749605386218,-0.40868858056019347,0.7217588966997998,-0.01690917370953021,-0.2667413189986047,2.1899853400179143,-0.38473594847995757,-0.5798253703616462,1.0895765601315317,1.8016559746006866 3430 Regulation of blood pressure 7 19 2.413516254143361 0.0157994231651081 P42892,Q9Y5X3,Q9UIQ6,P42785,P09601,P20020,Q9HB40 Processes and pathways GO Biological process msigdb_gobp 161,270,143,47,17,278,55 3371,897,733,17,2583,278,47,161,2009,2714,2798,1902,1649,1914,2144,55,386,143,270 -1.5143297421023834,0.28357365910325655,0.406945511095729,4.05893051652828,-0.5302953342350691,1.1600736506845353,3.3551136813137883,1.8325459149864132,-0.24348703633272678,-0.6047865559806115,-0.6551091457204445,-0.19731314994998111,-0.08377571033449493,-0.19731314994998111,-0.2901087935675131,3.1769568474904344,0.8349190753908383,2.0290981867058675,1.1949644490190432 3430