term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Intrinsic component of organelle membrane 63 111 4.777555105684201 1.7743943205861257e-06 Q6ZRP7,Q9H3K2,Q9UH99,O60830,Q15629,Q99595,Q14739,O76024,P51572,Q96A33,Q8WVX9,Q9H490,O00767,Q15125,Q5SNT2,Q9Y512,P42892,Q8TB61,O43808,Q86YN1,P27824,Q99442,P01889,Q86UP2,O95070,Q9Y2R0,Q86XL3,Q9BTV4,Q13505,P20020,P57088,Q9NX63,Q9UBM7,O43752,O43505,Q9HC21,O75880,Q8TCT9,P12235,O15258,Q9Y4P3,P56589,P13473,O15118,P04439,Q15041,O96008,A0FGR8,O14925,Q9NQC3,O75431,Q9BUN8,Q9BUR5,P50416,Q9Y282,Q15070,P10321,Q16891,Q5XKP0,O95470,Q12981,Q9P035,O75844 Localization GO Cellular component msigdb_gocc 258,389,525,9,10,11,266,393,273,274,539,289,283,166,559,565,43,44,549,174,556,176,302,305,179,55,56,581,58,436,316,461,325,189,195,324,568,202,447,445,205,449,210,85,333,223,466,589,464,96,97,229,367,485,109,360,481,363,502,250,499,260,127 589,1388,283,464,1390,85,445,1588,195,189,549,654,9,97,127,568,393,2649,1059,179,250,1456,466,302,333,481,447,210,436,773,2764,556,2885,3220,43,485,1019,273,449,316,852,1548,664,499,58,2045,266,1425,223,360,166,1360,10,940,363,698,1135,559,502,1313,784,258,305,56,828,174,829,2573,2056,912,1493,44,202,539,1497,1092,274,628,176,11,1376,2693,581,229,367,1378,389,289,1002,2960,324,1217,96,1710,878,461,2003,685,260,1269,325,882,1048,525,109,55,2591,205,734,565,1224 0.5134346459158582,-0.02198676428679048,1.1254866370979533,0.6866243286062695,-0.02198676428679048,2.7359582136753127,0.7108269558541094,-0.10815269963874782,1.605007630123358,1.6247393272059847,0.5636060512556167,0.4371047742428398,4.521067264147013,2.4171181472402936,2.16231565108635,0.5385907773537494,0.8299141117114622,-0.5982416058990344,0.14549770029311399,1.7028121530513547,1.276921824455599,-0.05052375805598644,0.6866243286062695,1.081263578277897,0.9687588066338071,0.6622900003005412,0.7108269558541094,1.5452878774447738,0.7348993205919421,0.3332580754721944,-0.6634903102109926,0.5636060512556167,-0.7632007073119792,-1.1493154316371736,3.34039786005235,0.6622900003005412,0.17280963840827135,1.1692778855749448,0.7108269558541094,1.0365999791862452,0.2804141068248859,-0.07924492702588042,0.4371047742428398,0.6378225083090472,3.2036080031326675,-0.28566029525923553,1.2126457954814382,-0.02198676428679048,1.4644074828289309,0.8998745416649946,1.7985369233817154,0.0063684354015670136,4.2752571823438945,0.22693649856222178,0.8998745416649946,0.41136873678446767,0.11801732694304702,0.5636060512556167,0.6378225083090472,0.034544176031171075,0.3332580754721944,1.2555985905367433,1.081263578277897,3.217473640342642,0.30691434248850596,1.722120594018782,0.30691434248850596,-0.5339391468977894,-0.28566029525923553,0.2537554699892711,-0.05052375805598644,3.34039786005235,1.5851890116525102,0.588482059091134,-0.05052375805598644,0.14549770029311399,1.1692778855749448,0.488136037900703,1.722120594018782,4.253245556056843,0.0063684354015670136,-0.5982416058990344,0.5385907773537494,1.4234149403548129,0.8998745416649946,0.0063684354015670136,0.8533559354124849,1.1254866370979533,0.1999552233330087,-0.7969425638483784,1.014100175743301,0.09036639678564706,2.433605013064534,-0.1372495529245524,0.2804141068248859,0.7108269558541094,-0.25557908848123395,0.4371047742428398,1.2555985905367433,0.06254274771127205,1.014100175743301,0.2804141068248859,0.17280963840827135,0.6132203653820887,2.333769977004763,3.231297118912164,-0.5339391468977894,1.5851890116525102,0.3854834577363446,0.5636060512556167,0.09036639678564706 3367 Lysosome 28 51 4.680956708564361 2.8553923807628223e-06 P15586,Q14108,P11279,P06280,P50897,P10253,P16278,P17900,Q15904,P04066,P20645,Q8NCC3,P10619,P07602,P61916,O14773,Q13510,P06865,P13473,P54802,O15118,Q9Y487,P11717,Q93050,O75503,P11117,P04062,O00462 Processes and pathways KEGG Pathways msigdb_kegg 128,5,261,139,26,163,41,169,173,184,185,63,190,65,197,70,78,81,210,83,85,215,217,92,102,108,118,126 2171,126,480,1452,70,85,738,1653,102,118,184,139,81,65,1064,554,1594,163,190,108,261,217,210,555,128,41,169,185,3354,26,1125,83,1544,746,197,817,1743,78,5,173,63,1980,92,507,1837,276,585,2294,2998,844,215 -0.34644068419145774,2.1797569087503486,0.6622900003005412,-0.05052375805598644,2.9465065973455364,2.7359582136753127,0.3594471701790773,-0.1372495529245524,2.40057096317167,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,0.5636060512556167,-0.10815269963874782,1.8362643641609107,1.6247393272059847,2.333769977004763,1.2341735778065615,1.5050295510613063,1.5452878774447738,0.5636060512556167,2.16231565108635,3.367269068562799,1.7413465847323417,1.6639450277501382,-1.951622338591048,3.6904275097045454,0.11801732694304702,2.7513259355917703,-0.07924492702588042,0.3594471701790773,1.605007630123358,0.30691434248850596,-0.16653801380920247,2.8724277004854066,4.744465578955981,1.722120594018782,3.1336381893089387,-0.25557908848123395,2.5793442451134623,0.6378225083090472,-0.19602066046695343,1.1692778855749448,0.5385907773537494,-0.37714563952921315,-0.8309434988946349,0.30691434248850596,1.525203768425511 3367 Intrinsic component of plasma membrane 41 72 4.585229269382072 4.534885386764387e-06 O00560,Q99808,Q9H0U3,Q9UNK0,P11279,P51572,Q9UJS0,O96005,O43657,Q8N2K0,P19022,Q99996,O60637,Q9Y4G8,P35613,Q15043,P16615,P01889,P27824,Q86UP2,P20020,P20645,P41440,O15031,Q8WTV0,P02786,P12235,Q9NR28,O15118,P04439,P30825,P05067,P11717,Q13641,Q92542,P53985,Q9UIQ6,O00264,P10321,Q99805,P27105 Localization GO Cellular component msigdb_gocc 495,259,387,526,261,273,546,150,24,419,286,160,31,564,165,293,290,302,556,305,436,185,186,314,60,200,447,213,85,333,89,90,217,346,227,103,105,106,481,379,124 589,106,495,1648,314,1114,85,1524,24,1279,31,892,150,302,200,333,610,90,553,1531,481,692,261,217,447,290,286,436,185,124,556,89,2031,165,2187,186,273,103,1126,2322,1548,980,1476,1131,2613,2330,346,293,3277,906,1032,305,419,1693,1206,60,227,1037,379,259,160,678,1510,387,2292,213,2079,105,546,1581,526,564 0.5134346459158582,2.333769977004763,0.6378225083090472,-0.1372495529245524,1.0365999791862452,0.11801732694304702,2.7359582136753127,-0.07924492702588042,3.8135378593665643,0.034544176031171075,3.5639012562238195,0.2537554699892711,1.9840930614703445,1.081263578277897,1.5851890116525102,0.9687588066338071,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,0.6622900003005412,0.41136873678446767,1.2341735778065615,1.5050295510613063,0.7108269558541094,1.1034296234289172,1.1254866370979533,0.7348993205919421,1.6639450277501382,2.19713106377011,0.5636060512556167,2.6583280208911844,-0.28566029525923553,1.7985369233817154,-0.34644068419145774,1.6639450277501382,1.1692778855749448,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.07924492702588042,0.1999552233330087,-0.05052375805598644,0.11801732694304702,-0.5659738392609449,-0.40806438662984673,0.9459148854023514,1.1034296234289172,-1.3366301135330916,0.2537554699892711,0.17280963840827135,1.081263578277897,0.7826588994764823,-0.1372495529245524,0.09036639678564706,3.1896999455248927,1.443957948969997,0.17280963840827135,0.8766756507402944,1.2555985905367433,1.8736785287250628,0.4371047742428398,-0.05052375805598644,0.8533559354124849,-0.37714563952921315,1.525203768425511,-0.28566029525923553,2.36729383704207,0.588482059091134,-0.07924492702588042,0.6132203653820887,0.5636060512556167 3367 Ion transmembrane transporter activity 40 80 4.430133984048695 9.41745591998e-06 Q99808,Q9H0U3,Q9BVC6,O43772,O75746,Q6P4Q7,P51798,P21796,Q9UBX3,P45880,Q9Y277,P00403,Q70HW3,Q9UJS0,P24539,P13073,Q9UDW1,Q15043,P16615,Q8TB61,O75964,O43808,P05141,P20020,P06576,P12236,P41440,Q9H2D1,Q9HC21,Q13423,Q9C0H2,P12235,Q9Y487,P30825,Q93050,P53985,P47985,Q9HD20,P25705,O95202 Functions GO Molecular function msigdb_gomf 259,387,385,134,381,400,516,13,18,19,548,145,22,546,411,167,40,293,290,44,45,549,553,436,435,307,186,61,324,71,72,447,215,89,92,103,484,115,244,123 2645,2363,738,134,549,381,1938,45,123,1456,145,610,553,435,2370,1655,807,970,2180,1872,692,447,307,167,290,436,1797,1537,2377,13,411,244,89,3038,2318,1539,2976,186,19,484,3321,516,1071,103,2322,1073,1127,746,852,1548,980,71,2505,293,906,2340,599,1822,400,22,1493,44,1038,92,259,385,72,387,61,2636,1002,324,115,18,40,585,546,548,215,2536 -0.5982416058990344,-0.43919996831517205,0.3594471701790773,2.1095839500852342,0.5636060512556167,0.8533559354124849,-0.25557908848123395,3.286174597616811,2.19713106377011,-0.05052375805598644,2.002235460610414,0.488136037900703,0.5636060512556167,0.7348993205919421,-0.43919996831517205,-0.1372495529245524,0.30691434248850596,0.1999552233330087,-0.34644068419145774,-0.22570012371921228,0.41136873678446767,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,4.220028343416946,0.7826588994764823,1.3192668476331657,2.6583280208911844,-0.8997389788237078,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,1.6639450277501382,3.9215673900004977,0.6622900003005412,-1.5724386516725661,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,0.2804141068248859,-0.07924492702588042,0.1999552233330087,2.9465065973455364,-0.5021341373910327,1.1034296234289172,0.2537554699892711,-0.40806438662984673,0.5134346459158582,-0.19602066046695343,0.8299141117114622,3.8256681593087887,-0.05052375805598644,3.34039786005235,0.17280963840827135,2.5793442451134623,1.2555985905367433,0.8533559354124849,2.9465065973455364,0.8533559354124849,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,4.015494309311654,3.380645404831543,0.5385907773537494,0.588482059091134,0.588482059091134,1.525203768425511,-0.5021341373910327 3367 Endoplasmic reticulum 177 451 4.294450494691417 1.7512655205553784e-05 P09601,P30519,P24390,O00560,Q9UNK0,Q14108,Q14849,Q5BJF2,Q9BQE5,Q15629,Q92791,O75352,P80303,P43307,Q9BVK6,Q8NHH9,Q99720,P48651,Q8TB61,Q8TED1,Q02818,Q8N0U8,Q8N511,Q13217,Q9H6V9,P27824,P15289,Q9P2W9,Q86XL3,Q9BTV4,Q9H4L5,P07099,Q96G23,Q99943,Q96AG4,Q15800,P49257,Q9UMX5,O15173,Q9Y3B3,Q15392,Q06136,Q13510,O15118,Q9UQB8,P51648,P05067,Q96KC8,P67812,Q16850,Q9NQC3,P48449,Q96N66,O75503,Q9Y282,O00264,O95197,Q9HD20,O00584,P04062,Q9Y5M8,O15260,P27105,O75844,Q07065,Q9H1C4,Q8IV08,Q32P28,Q70UQ0,Q99735,Q9BRK5,O60725,Q14257,Q86UE4,Q9BRR6,P35613,Q15125,Q9NZ08,Q96LJ7,Q15904,Q86YN1,Q99442,Q9Y680,Q01105,O95070,P46977,P50402,P30536,P10619,O43852,P61916,Q8TCT9,Q9Y4P3,Q10472,O75718,Q15041,P16435,O15269,Q92542,Q9BUN8,P48723,O60476,Q96PC5,Q92604,Q2TAA5,Q9BTY2,O95470,Q9P035,P04843,Q14739,Q6ZXV5,Q9P2J5,P51572,Q96A33,Q9H490,P19022,O00767,Q53GQ0,Q9Y3E0,Q96RL7,Q9BU23,P16615,O00429,P01889,P13674,Q86UP2,Q96GC9,P35610,A1L0T0,P57088,Q9UBM7,Q12768,Q8WXH0,Q96HY6,Q8TCJ2,Q14534,P04439,Q6IAN0,Q13641,P42858,Q13190,Q9BUR5,Q9P2K2,Q8NFQ8,O60506,Q9Y678,Q9H2J4,Q9H0U3,Q9BVC6,P38435,O95674,O76024,Q8NBQ5,Q8N2K0,Q9Y320,Q8IY95,Q6NUM9,O43390,Q8NBM4,Q6NUQ1,Q03001,P49755,Q8WVQ1,O15258,P56589,Q9H3N1,P27544,Q9NUQ7,Q9BZF1,P37268,P10321,Q9NX47,Q9NTJ5,Q8N2G8,Q12981,P42345,P35606 Localization GO Cellular component msigdb_gocc 0,1,2,495,526,5,6,7,8,10,12,514,15,17,541,538,28,533,44,560,46,47,48,558,50,556,555,54,56,581,582,59,66,580,578,69,572,73,74,75,76,77,78,85,86,88,90,91,93,94,96,98,101,102,109,106,107,115,116,118,120,121,124,127,131,133,136,140,141,147,148,144,151,153,161,165,166,168,172,173,174,176,178,181,179,188,193,191,190,196,197,202,205,208,206,223,222,220,227,229,231,235,238,245,248,249,250,260,254,266,267,272,273,274,289,286,283,295,299,297,298,290,300,302,303,305,310,308,313,316,325,321,331,342,341,339,333,349,346,344,355,367,380,377,371,391,388,387,385,383,395,393,403,419,420,417,415,409,425,424,423,437,457,445,449,472,467,493,491,483,481,510,509,505,499,498,497 589,313,1111,1340,106,300,2093,495,116,283,3347,1113,737,800,1390,801,85,74,445,121,220,965,2019,3065,1524,1588,2173,2478,409,1453,1860,738,196,235,2302,371,1526,144,1654,691,634,2544,514,2367,102,3294,206,127,1168,393,2547,1229,636,1867,2023,967,1230,179,107,926,2481,250,1170,1282,1171,395,2101,892,1172,968,1457,2808,302,118,333,928,254,1173,610,90,3301,637,59,1345,2177,2105,0,2181,481,190,3213,2106,1941,303,972,2600,1118,555,222,290,1346,1400,286,929,3264,774,2314,2929,2656,3036,1459,2,3148,1945,2813,2029,124,2763,467,1233,3070,2764,556,612,2431,3150,2250,2113,2885,1,639,191,2491,2379,1798,1662,497,308,165,2889,1237,483,383,1601,498,344,17,1947,1881,1665,188,1949,98,533,231,2435,1732,572,897,437,193,2321,1124,273,88,1020,1605,2723,1670,1125,2258,2818,2895,1805,2896,449,1545,316,3286,3222,2845,1606,899,2194,933,2259,2438,1807,852,2196,197,1737,2725,1954,1295,1738,2261,2560,1190,3322,3158,1810,3127,93,15,1351,935,1240,574,181,3223,854,46,1812,423,1415,2396,77,1475,131,695,664,208,321,1744,2612,1131,2613,1815,499,1193,355,558,1553,78,821,1891,346,2126,5,858,2503,822,151,2045,339,1746,266,6,2046,1025,1425,223,1817,1613,2615,166,1361,3277,76,2616,1556,1307,10,2274,1247,69,173,94,248,140,295,2678,7,1135,1428,1429,700,646,349,1313,415,424,600,1822,3101,1753,1029,267,141,1624,153,622,305,56,174,2407,1904,136,1758,625,830,417,47,505,419,48,1433,912,702,2346,425,403,2783,868,1367,377,538,1206,2830,44,1911,1628,341,1826,202,995,560,832,754,1696,457,331,227,1317,245,1497,3363,12,2410,2907,1092,1566,274,578,916,1368,3337,66,310,2739,342,91,172,101,238,297,628,2580,176,3260,3109,3280,2459,28,147,580,8,148,161,1509,2693,630,581,249,298,229,367,385,541,491,1841,1100,1843,387,133,649,388,955,472,1440,289,582,1573,1633,50,1216,1217,115,1218,96,795,682,509,2913,493,510,2798,796,2003,1006,685,168,260,1155,1269,272,380,54,2468,325,687,2469,766,1106,2162,2470,3229,73,3312,526,1931,1337,86,1160,109,3144,1584,420,1585,75,299,3084,1163,1164,205,120,391,1224,178,1586 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3367 Vacuolar lumen 25 65 4.226315856177097 2.375484943728523e-05 P15586,Q14108,Q8IV08,P06280,Q9UM22,P50897,P10253,P16278,P17900,Q8NHP8,P04066,P10619,P07602,Q9H7Z7,P61916,O14773,Q13510,P06865,P13473,P54802,P11117,O00584,P04062,Q9BTY2,O00462 Localization GO Cellular component msigdb_gocc 128,5,136,139,14,26,163,41,169,49,184,190,65,67,197,70,78,81,210,83,108,116,118,249,126 126,495,116,480,70,738,2808,118,184,139,81,2370,2025,65,1064,969,163,190,108,1940,1873,210,555,128,41,169,2111,2431,2186,383,3354,1800,2436,26,2606,1886,1125,1021,83,2818,2391,197,1740,1129,1961,2396,558,78,5,1892,136,2783,49,322,1368,998,675,507,249,680,67,3060,276,14,2702 2.1797569087503486,0.6378225083090472,2.248856101291637,0.6622900003005412,2.9465065973455364,0.3594471701790773,-0.6964784202356398,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,-0.43919996831517205,-0.28566029525923553,3.0911332595741183,0.14549770029311399,0.1999552233330087,1.8362643641609107,1.6247393272059847,2.333769977004763,-0.25557908848123395,-0.22570012371921228,1.5452878774447738,0.5636060512556167,2.16231565108635,3.367269068562799,1.7413465847323417,-0.31594654169938047,-0.4705554931571856,-0.34644068419145774,0.8533559354124849,-1.951622338591048,-0.19602066046695343,-0.4705554931571856,3.6904275097045454,-0.5659738392609449,-0.22570012371921228,0.11801732694304702,0.17280963840827135,2.7513259355917703,-0.6964784202356398,-0.43919996831517205,1.605007630123358,-0.16653801380920247,0.11801732694304702,-0.25557908848123395,-0.43919996831517205,0.5636060512556167,2.8724277004854066,4.744465578955981,-0.22570012371921228,2.0918689378538042,-0.6634903102109926,3.286174597616811,1.014100175743301,0.0063684354015670136,0.1999552233330087,0.4371047742428398,0.6378225083090472,1.2981442560194676,0.4371047742428398,3.062574077848557,-0.8997389788237078,1.1692778855749448,4.1865682400285555,-0.5982416058990344 3367 Intrinsic component of endoplasmic reticulum membrane 23 48 4.179137737771008 2.9261643025524364e-05 Q15629,P51572,Q96A33,Q9H490,O00767,Q15125,Q8TB61,P01889,Q86YN1,Q99442,Q86UP2,Q86XL3,P57088,Q9UBM7,Q8TCT9,Q9Y4P3,Q15041,Q9NQC3,Q9BUN8,Q9Y282,O95470,Q9P035,O75844 Localization GO Cellular component msigdb_gocc 10,273,274,289,283,166,44,302,174,176,305,56,316,325,202,205,223,96,229,109,250,260,127 589,283,1390,1588,127,393,250,302,333,481,2764,556,2885,273,316,852,499,2045,1425,223,166,10,1135,1313,305,56,174,912,44,202,1497,1092,274,628,176,2693,229,289,1217,96,2003,685,260,1269,325,109,205,1224 0.5134346459158582,1.1254866370979533,-0.02198676428679048,-0.10815269963874782,2.16231565108635,0.8299141117114622,1.276921824455599,1.081263578277897,0.9687588066338071,0.6622900003005412,-0.6634903102109926,0.5636060512556167,-0.7632007073119792,1.1692778855749448,1.0365999791862452,0.2804141068248859,0.6378225083090472,-0.28566029525923553,-0.02198676428679048,1.4644074828289309,1.7985369233817154,4.2752571823438945,0.11801732694304702,0.034544176031171075,1.081263578277897,3.217473640342642,1.722120594018782,0.2537554699892711,3.34039786005235,1.5851890116525102,-0.05052375805598644,0.14549770029311399,1.1692778855749448,0.488136037900703,1.722120594018782,-0.5982416058990344,1.4234149403548129,1.1254866370979533,0.09036639678564706,2.433605013064534,-0.25557908848123395,0.4371047742428398,1.2555985905367433,0.06254274771127205,1.014100175743301,2.333769977004763,1.5851890116525102,0.09036639678564706 3367 Lysosomal lumen 22 36 4.173401824920309 3.000850023160417e-05 P15586,Q14108,Q8IV08,P06280,Q9UM22,P50897,P10253,P16278,P17900,Q8NHP8,P04066,P10619,P07602,P61916,O14773,Q13510,P06865,P54802,P11117,O00584,P04062,O00462 Localization GO Cellular component msigdb_gocc 128,5,136,139,14,26,163,41,169,49,184,190,65,197,70,78,81,83,108,116,118,126 126,116,480,70,738,118,184,139,81,65,1064,969,163,190,108,1940,210,555,128,41,169,383,3354,1800,26,83,197,78,5,136,2783,49,507,680,276,14 2.1797569087503486,2.248856101291637,0.6622900003005412,2.9465065973455364,0.3594471701790773,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,0.1999552233330087,1.8362643641609107,1.6247393272059847,2.333769977004763,-0.25557908848123395,1.5452878774447738,0.5636060512556167,2.16231565108635,3.367269068562799,1.7413465847323417,0.8533559354124849,-1.951622338591048,-0.19602066046695343,3.6904275097045454,2.7513259355917703,1.605007630123358,2.8724277004854066,4.744465578955981,2.0918689378538042,-0.6634903102109926,3.286174597616811,0.6378225083090472,0.4371047742428398,1.1692778855749448,4.1865682400285555 3367 Transporter activity 66 144 4.136625933293034 3.524499620666255e-05 Q99808,Q9H0U3,Q9NS69,O43676,Q9BVC6,Q14849,O43772,P38435,O60830,O75746,Q99595,P51798,P21796,Q6P4Q7,Q9UBX3,P45880,Q9Y277,P00403,Q70HW3,Q9UJS0,P24539,Q6NT16,P13073,Q9UDW1,Q15043,P16615,Q8TB61,O75964,O43808,P17900,P49755,P05141,Q8IXU6,Q96GC9,P20020,P06576,P12236,Q9H4L5,P41440,Q8WTV0,Q9H2D1,P30536,Q9HC21,P61916,Q13423,Q9C0H2,O15173,P12235,Q9BSK2,O15118,Q9Y487,P30825,Q8NE01,Q93050,O96008,O14925,Q9BZF1,Q9P0J0,P53985,P47985,P08183,Q9HD20,P25705,P04062,P28288,O95202 Functions GO Molecular function msigdb_gomf 259,387,3,4,385,6,134,383,9,381,11,516,13,400,18,19,548,145,22,546,411,32,167,40,293,290,44,45,549,169,437,553,52,310,436,435,307,582,186,60,61,191,324,197,71,72,74,447,209,85,215,89,351,92,466,464,491,230,103,484,110,115,244,118,372,123 1388,3313,2645,1389,2363,464,1390,85,74,1588,4,738,134,549,9,1015,2096,1057,2242,381,1938,45,2649,2243,3233,123,2969,1456,2024,466,145,118,610,553,435,2370,1655,110,807,970,2180,1872,692,447,307,167,290,169,3192,436,1797,1537,2377,13,2314,411,244,372,3173,191,89,3038,2318,1539,383,2976,186,19,484,3321,2435,437,3095,516,661,1293,1070,1071,103,2322,1073,1127,3286,746,852,197,1547,1548,980,71,1194,2505,6,293,906,2506,2336,2340,32,599,1822,400,22,52,1694,351,1493,44,60,1038,92,310,1096,1375,11,259,2692,209,385,1990,491,72,387,761,61,582,2636,1002,324,115,1710,3,230,18,40,766,585,546,1159,1009,548,215,2536,1110 -0.02198676428679048,-1.5322507832020744,-0.5982416058990344,-0.02198676428679048,-0.43919996831517205,0.6866243286062695,-0.02198676428679048,2.7359582136753127,2.9317872528718985,-0.10815269963874782,4.744465578955981,0.3594471701790773,2.1095839500852342,0.5636060512556167,4.521067264147013,0.17280963840827135,-0.31594654169938047,0.14549770029311399,-0.37714563952921315,0.8533559354124849,-0.25557908848123395,3.286174597616811,-0.5982416058990344,-0.37714563952921315,-1.1861480785988963,2.19713106377011,-0.8309434988946349,-0.05052375805598644,-0.28566029525923553,0.6866243286062695,2.002235460610414,2.248856101291637,0.488136037900703,0.5636060512556167,0.7348993205919421,-0.43919996831517205,-0.1372495529245524,2.2999956417932186,0.30691434248850596,0.1999552233330087,-0.34644068419145774,-0.22570012371921228,0.41136873678446767,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,1.7413465847323417,-1.112787329154505,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,4.220028343416946,-0.40806438662984673,0.7826588994764823,1.3192668476331657,0.8766756507402944,-1.0765587039609845,1.6247393272059847,2.6583280208911844,-0.8997389788237078,-0.40806438662984673,-0.07924492702588042,0.8533559354124849,-0.8309434988946349,1.6639450277501382,3.9215673900004977,0.6622900003005412,-1.5724386516725661,-0.4705554931571856,0.7348993205919421,-0.969620885690122,0.6132203653820887,0.4371047742428398,0.034544176031171075,0.14549770029311399,0.14549770029311399,2.40057096317167,-0.40806438662984673,0.14549770029311399,0.11801732694304702,-1.37506621536203,0.3594471701790773,0.2804141068248859,1.605007630123358,-0.07924492702588042,-0.07924492702588042,0.1999552233330087,2.9465065973455364,0.09036639678564706,-0.5021341373910327,4.664482621298005,1.1034296234289172,0.2537554699892711,-0.5021341373910327,-0.40806438662984673,-0.40806438662984673,3.5639012562238195,0.5134346459158582,-0.19602066046695343,0.8299141117114622,3.8256681593087887,3.258818635054596,-0.1372495529245524,0.9459148854023514,-0.05052375805598644,3.34039786005235,3.1896999455248927,0.17280963840827135,2.5793442451134623,1.058987402257529,0.14549770029311399,0.0063684354015670136,4.253245556056843,1.2555985905367433,-0.5982416058990344,1.5652826911718993,0.8533559354124849,-0.25557908848123395,0.6622900003005412,2.9465065973455364,0.8533559354124849,0.3594471701790773,3.161755509768943,0.5385907773537494,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,-0.1372495529245524,4.832811783410612,1.4234149403548129,4.015494309311654,3.380645404831543,0.3594471701790773,0.5385907773537494,0.588482059091134,0.11801732694304702,0.1999552233330087,0.588482059091134,1.525203768425511,-0.5021341373910327,0.14549770029311399 3367 Anion transport 29 59 4.103915968081418 4.062150619654759e-05 Q99808,O75746,P51798,P21796,Q13131,Q9UBX3,P45880,Q9NZJ7,Q9Y277,Q9UJS0,O60831,Q9UHG3,Q15043,Q8TB61,O43808,P12236,P41440,Q9H2D1,P30536,P07602,Q9HC21,Q9C0H2,P12235,P80404,P30825,Q15041,P53985,P08183,P28288 Processes and pathways GO Biological process msigdb_gobp 259,381,516,13,519,18,19,276,548,546,158,37,293,44,549,307,186,61,191,65,324,72,447,211,89,223,103,110,372 2645,2363,738,549,158,381,1168,1456,2484,553,1531,65,110,807,2180,692,447,307,893,13,372,191,89,186,19,516,1071,103,1887,2322,211,1548,980,519,1304,223,1817,293,906,2340,599,1822,44,259,72,1213,61,2636,1002,324,1709,276,18,37,2470,546,548,2088,2536 -0.5982416058990344,-0.43919996831517205,0.3594471701790773,0.5636060512556167,1.9292237974120185,0.8533559354124849,0.09036639678564706,-0.05052375805598644,-0.5021341373910327,0.5636060512556167,-0.07924492702588042,3.0911332595741183,2.2999956417932186,0.30691434248850596,-0.34644068419145774,0.41136873678446767,0.7108269558541094,1.058987402257529,0.2537554699892711,4.220028343416946,0.8766756507402944,1.6247393272059847,2.6583280208911844,1.6639450277501382,3.9215673900004977,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.22570012371921228,-0.40806438662984673,1.525203768425511,-0.07924492702588042,0.1999552233330087,0.6132203653820887,0.034544176031171075,1.4644074828289309,-0.19602066046695343,1.1034296234289172,0.2537554699892711,-0.40806438662984673,0.5134346459158582,-0.19602066046695343,3.34039786005235,1.2555985905367433,2.9465065973455364,0.09036639678564706,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,-0.1372495529245524,1.1692778855749448,4.015494309311654,3.473195069920084,-0.4705554931571856,0.588482059091134,0.588482059091134,-0.28566029525923553,-0.5021341373910327 3367 Receptor 18 35 4.049001755813488 5.143655895567534e-05 P30825,P24390,Q9NS69,P11717,Q14108,P11279,P35613,P02786,Q5KU26,Q14739,O15173,O00264,Q8WTV0,P55899,O15118,Q9Y5M8,P20645,Q99720 Functions Protein Atlas Molecular function protein_atlas_molecular_function 89,2,3,217,5,261,165,200,171,266,74,106,60,180,85,120,185,28 106,1648,314,85,74,200,1531,637,2177,2715,2181,261,217,2109,185,2,89,165,180,1476,2330,5,858,266,906,171,60,1038,1507,28,3,511,586,120,2705 2.333769977004763,-0.1372495529245524,1.0365999791862452,2.7359582136753127,2.9317872528718985,1.5851890116525102,-0.07924492702588042,0.46269330605308917,-0.34644068419145774,-0.6307459142786708,-0.34644068419145774,1.2341735778065615,1.5050295510613063,-0.31594654169938047,1.6639450277501382,5.106453588871854,2.6583280208911844,1.7985369233817154,1.7028121530513547,-0.05052375805598644,-0.40806438662984673,4.744465578955981,0.2804141068248859,1.2126457954814382,0.2537554699892711,1.7413465847323417,3.1896999455248927,0.17280963840827135,-0.05052375805598644,3.665401627508389,4.832811783410612,0.6378225083090472,0.5385907773537494,2.2316801472635333,-0.5982416058990344 3367 Membrane lipid metabolic process 18 35 4.021546243143501 5.781735422760725e-05 O15269,Q96G23,P07602,P16278,O95470,P06280,P17900,Q06136,Q13510,Q99735,P06865,Q8NBX0,Q9NZJ7,P04062,P04066,P50897,Q9P035,Q8NCC3 Processes and pathways GO Biological process msigdb_gobp 220,66,65,41,250,139,169,77,78,147,81,114,276,118,184,26,260,63 220,965,1654,250,118,184,139,81,65,1064,41,169,2314,467,1405,26,2396,77,519,78,698,114,63,1497,1092,66,628,147,379,289,796,685,276,260,1155 1.4644074828289309,0.1999552233330087,-0.1372495529245524,1.276921824455599,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,3.367269068562799,1.7413465847323417,-0.40806438662984673,0.6866243286062695,-0.02198676428679048,3.6904275097045454,-0.43919996831517205,2.8724277004854066,0.6132203653820887,2.8724277004854066,0.41136873678446767,2.283013353361886,3.1336381893089387,-0.05052375805598644,0.14549770029311399,3.0911332595741183,0.488136037900703,2.002235460610414,0.8766756507402944,1.1254866370979533,0.3332580754721944,0.4371047742428398,1.1692778855749448,1.2555985905367433,0.11801732694304702 3367 Predicted secreted proteins 19 48 3.939794443898 8.155145477295456e-05 Q15165,Q9UM22,P80303,Q08380,Q9HB40,Q9NZ08,Q8WUJ1,Q02818,P61916,P02786,Q9UMX5,Q9Y4P3,O75718,P43490,P05067,Q9BUR5,O00584,O60888,Q9BTY2 Functions Protein Atlas Protein class protein_atlas_protein_class 135,14,15,146,34,168,42,46,197,200,73,205,206,335,90,367,116,117,249 116,1648,1526,117,206,594,200,2484,90,1795,2370,1656,2106,893,2109,772,3036,1403,715,335,2556,1670,1805,197,15,1958,46,1549,146,695,2612,2330,135,3323,42,2907,1915,249,367,1510,2150,1573,34,168,380,14,73,205 2.248856101291637,-0.1372495529245524,-0.07924492702588042,2.248856101291637,1.5652826911718993,0.5134346459158582,1.5851890116525102,-0.5021341373910327,2.595251590463738,-0.19602066046695343,-0.43919996831517205,-0.1372495529245524,-0.31594654169938047,0.2537554699892711,-0.31594654169938047,0.3332580754721944,-0.8997389788237078,-0.02198676428679048,0.3854834577363446,0.9687588066338071,-0.5339391468977894,-0.1372495529245524,-0.19602066046695343,1.605007630123358,4.164124775027304,-0.25557908848123395,3.286174597616811,-0.07924492702588042,2.002235460610414,0.41136873678446767,-0.5659738392609449,-0.40806438662984673,2.0918689378538042,-1.5724386516725661,3.3538532991819987,-0.7632007073119792,-0.22570012371921228,1.2981442560194676,0.8998745416649946,-0.05052375805598644,-0.31594654169938047,-0.07924492702588042,3.525248122809391,1.7795540517583925,0.8766756507402944,4.1865682400285555,2.9465065973455364,1.5851890116525102 3367 SLC superfamily of solute carriers 19 38 3.877557829450608 0.0001055102532292 Q99808,Q9H0U3,O43772,Q9UBX3,Q9NZJ7,Q70HW3,Q6NT16,Q15043,Q8TB61,Q9Y6C9,Q8IXU6,P12236,P41440,Q9H2D1,Q9HC21,Q9BSK2,P30825,P53985,O95202 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 259,387,134,18,276,22,32,293,44,306,52,307,186,61,324,209,89,103,123 1390,134,549,381,123,1456,553,807,692,447,307,89,186,1071,103,2322,1548,980,293,906,2340,32,599,1822,22,52,44,259,209,387,61,2636,1002,324,276,18,546,306 -0.02198676428679048,2.1095839500852342,0.5636060512556167,0.8533559354124849,2.19713106377011,-0.05052375805598644,0.5636060512556167,0.30691434248850596,0.41136873678446767,0.7108269558541094,1.058987402257529,2.6583280208911844,1.6639450277501382,0.14549770029311399,2.40057096317167,-0.40806438662984673,-0.07924492702588042,0.1999552233330087,1.1034296234289172,0.2537554699892711,-0.40806438662984673,3.5639012562238195,0.5134346459158582,-0.19602066046695343,3.8256681593087887,3.258818635054596,3.34039786005235,1.2555985905367433,1.5652826911718993,0.8533559354124849,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,1.1692778855749448,4.015494309311654,0.588482059091134,1.081263578277897 3367 Azurophil granule 23 68 3.869960007485802 0.0001088532082678 P15586,Q07065,P11279,P06280,Q9NZJ7,P42785,P10253,P16278,P17900,P04066,P10619,P07602,Q9H7Z7,P61916,P06865,P13473,O15260,Q92542,O00584,O95721,Q9BTY2,P27105,O00462 Localization GO Cellular component msigdb_gocc 128,131,261,139,276,21,163,41,169,184,190,65,67,197,81,210,121,227,116,247,249,124,126 126,495,116,480,121,446,738,1227,1527,247,2808,184,139,81,2370,2025,65,1064,163,190,1873,261,210,555,128,41,169,2111,124,2431,2186,1601,21,2436,2606,976,977,1886,1125,1021,2818,2391,197,1740,1129,1961,2396,131,558,1892,501,598,2783,1367,227,322,2064,1368,998,675,2692,249,387,67,3060,276,1155,2702 2.1797569087503486,0.6378225083090472,2.248856101291637,0.6622900003005412,2.214438638015626,0.7108269558541094,0.3594471701790773,0.06254274771127205,-0.07924492702588042,1.2981442560194676,-0.6964784202356398,1.6639450277501382,2.074084118777206,2.781905953857426,-0.43919996831517205,-0.28566029525923553,3.0911332595741183,0.14549770029311399,1.8362643641609107,1.6247393272059847,-0.22570012371921228,1.2341735778065615,1.5452878774447738,0.5636060512556167,2.16231565108635,3.367269068562799,1.7413465847323417,-0.31594654169938047,2.19713106377011,-0.4705554931571856,-0.34644068419145774,-0.10815269963874782,3.8498324746709085,-0.4705554931571856,-0.5659738392609449,0.1999552233330087,0.1999552233330087,-0.22570012371921228,0.11801732694304702,0.17280963840827135,-0.6964784202356398,-0.43919996831517205,1.605007630123358,-0.16653801380920247,0.11801732694304702,-0.25557908848123395,-0.43919996831517205,2.144806762718082,0.5636060512556167,-0.22570012371921228,0.6378225083090472,0.5134346459158582,-0.6634903102109926,0.0063684354015670136,1.443957948969997,1.014100175743301,-0.28566029525923553,0.0063684354015670136,0.1999552233330087,0.4371047742428398,-0.5982416058990344,1.2981442560194676,0.8533559354124849,3.062574077848557,-0.8997389788237078,1.1692778855749448,0.11801732694304702,-0.5982416058990344 3367 Vacuolar membrane 32 116 3.8578188697933817 0.0001144033761604 Q07065,Q14108,Q14849,Q8IV08,P11279,Q9NZJ7,P42785,O75955,P10253,Q96RL7,Q15043,P42892,Q8N511,P20645,P41440,Q8WTV0,P10619,P07602,P13473,O15118,Q9Y487,Q93050,Q92542,O75503,Q9UIQ6,P11117,Q16625,P04062,O95721,O15260,P27105,O00462 Localization GO Cellular component msigdb_gocc 131,5,6,136,261,276,21,162,163,297,293,43,48,185,186,60,190,65,210,85,215,92,227,102,105,108,242,118,247,121,124,126 2171,126,1452,85,121,633,446,3115,1653,690,1227,1527,102,162,1281,247,1062,118,1173,2370,65,1655,807,1065,2105,554,163,190,108,1940,261,210,185,1537,2377,2656,124,1235,613,1539,2976,1601,186,498,21,43,2552,977,1019,516,813,2896,1544,2845,2259,746,3157,1956,2125,817,981,131,1476,1890,1743,2043,5,6,293,242,598,136,417,48,1367,1089,60,1762,1763,227,92,1318,2064,835,1567,2525,310,1209,297,2788,2692,678,1837,1571,368,387,1921,1572,3209,1709,2963,2157,276,1155,2293,880,585,105,1520,3165,526,527,844,3299,215,2835 -0.34644068419145774,2.1797569087503486,-0.05052375805598644,2.7359582136753127,2.214438638015626,0.46269330605308917,0.7108269558541094,-1.004980242603473,-0.1372495529245524,0.41136873678446767,0.06254274771127205,-0.07924492702588042,2.40057096317167,1.8550102756937976,0.034544176031171075,1.2981442560194676,0.14549770029311399,2.248856101291637,0.09036639678564706,-0.43919996831517205,3.0911332595741183,-0.1372495529245524,0.30691434248850596,0.14549770029311399,-0.31594654169938047,0.5636060512556167,1.8362643641609107,1.6247393272059847,2.333769977004763,-0.25557908848123395,1.2341735778065615,1.5452878774447738,1.6639450277501382,-0.07924492702588042,-0.43919996831517205,-0.5982416058990344,2.19713106377011,0.06254274771127205,0.488136037900703,-0.07924492702588042,-0.8309434988946349,-0.10815269963874782,1.6639450277501382,0.6378225083090472,3.8498324746709085,3.34039786005235,-0.5339391468977894,0.1999552233330087,0.17280963840827135,0.6132203653820887,0.30691434248850596,-0.7632007073119792,-0.07924492702588042,-0.7297139540963061,-0.37714563952921315,0.3594471701790773,-1.0406246148817728,-0.25557908848123395,-0.31594654169938047,0.30691434248850596,0.1999552233330087,2.144806762718082,-0.05052375805598644,-0.22570012371921228,-0.16653801380920247,-0.28566029525923553,4.744465578955981,4.664482621298005,1.1034296234289172,1.3402905479186136,0.5134346459158582,2.0918689378538042,0.7826588994764823,3.286174597616811,0.0063684354015670136,0.14549770029311399,3.1896999455248927,-0.16653801380920247,-0.16653801380920247,1.443957948969997,2.5793442451134623,0.034544176031171075,-0.28566029525923553,0.30691434248850596,-0.07924492702588042,-0.5021341373910327,1.058987402257529,0.09036639678564706,1.1034296234289172,-0.6634903102109926,-0.5982416058990344,0.4371047742428398,-0.19602066046695343,-0.07924492702588042,0.8998745416649946,0.8533559354124849,-0.22570012371921228,-0.07924492702588042,-1.112787329154505,-0.1372495529245524,-0.7969425638483784,-0.31594654169938047,1.1692778855749448,0.11801732694304702,-0.37714563952921315,0.2804141068248859,0.5385907773537494,2.36729383704207,-0.05052375805598644,-1.0406246148817728,0.6132203653820887,0.6132203653820887,0.30691434248850596,-1.45295805178107,1.525203768425511,-0.6964784202356398 3367 Anion transmembrane transport 20 35 3.801951285692855 0.0001435609584812 O75746,P51798,P21796,Q9UBX3,P45880,Q9Y277,Q9UJS0,O60831,Q9UHG3,Q8TB61,O43808,P12236,P41440,Q9H2D1,Q9HC21,P12235,P30825,Q15041,P53985,P08183 Processes and pathways GO Biological process msigdb_gobp 381,516,13,18,19,548,546,158,37,44,549,307,186,61,324,447,89,223,103,110 549,158,381,1168,1456,553,1531,110,807,447,307,13,89,186,19,516,1071,103,2322,1548,980,1304,223,906,44,61,2636,1002,324,1709,18,37,546,548,2088 0.5636060512556167,1.9292237974120185,0.8533559354124849,0.09036639678564706,-0.05052375805598644,0.5636060512556167,-0.07924492702588042,2.2999956417932186,0.30691434248850596,0.7108269558541094,1.058987402257529,4.220028343416946,2.6583280208911844,1.6639450277501382,3.9215673900004977,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.40806438662984673,-0.07924492702588042,0.1999552233330087,0.034544176031171075,1.4644074828289309,0.2537554699892711,3.34039786005235,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,-0.1372495529245524,4.015494309311654,3.473195069920084,0.588482059091134,0.588482059091134,-0.28566029525923553 3367 Molecular transducer activity 12 30 3.7978007851173134 0.0001459855754912 P30536,P11717,Q14108,Q9BUN8,Q5KU26,Q15629,O15173,Q8WTV0,Q99442,O15118,P20645,Q99720 Functions GO Molecular function msigdb_gomf 191,217,5,229,171,10,74,60,176,85,185,28 1648,314,85,74,1279,1531,217,185,191,777,2188,743,1741,1476,2330,5,10,906,2206,171,1899,60,1038,176,28,229,2079,1269,766,1581 -0.1372495529245524,1.0365999791862452,2.7359582136753127,2.9317872528718985,0.034544176031171075,-0.07924492702588042,1.5050295510613063,1.6639450277501382,1.6247393272059847,0.3332580754721944,-0.34644068419145774,0.3594471701790773,-0.16653801380920247,-0.05052375805598644,-0.40806438662984673,4.744465578955981,4.2752571823438945,0.2537554699892711,-0.34644068419145774,1.7413465847323417,-0.22570012371921228,3.1896999455248927,0.17280963840827135,1.722120594018782,3.665401627508389,1.4234149403548129,-0.28566029525923553,0.06254274771127205,0.3594471701790773,-0.07924492702588042 3367 Nuclear outer membrane endoplasmic reticulum membrane network 121 281 3.7921750486935673 0.0001493335877496 O00560,P30519,P24390,P09601,Q14108,Q14849,Q5BJF2,Q9BQE5,Q15629,O75352,P43307,Q9BVK6,Q8NHH9,Q99720,Q8TB61,Q8N0U8,Q8N511,Q9P2W9,Q86XL3,P07099,Q96G23,Q15800,Q9Y3B3,Q15392,Q06136,P51648,Q96KC8,P67812,Q16850,Q9NQC3,P48449,Q96N66,Q9Y282,O00264,O95197,Q9HD20,Q9Y5M8,O15260,O75844,Q07065,Q9H1C4,Q8IV08,Q70UQ0,Q99735,O60725,Q86UE4,Q9BRR6,P35613,Q15125,Q9NZ08,Q15904,Q86YN1,Q99442,O95070,P46977,P50402,O43852,Q8TCT9,Q9Y4P3,Q10472,Q15041,P16435,O15269,Q9BUN8,Q96PC5,Q92604,Q2TAA5,O95470,Q9P035,P04843,Q14739,P51572,Q96A33,Q9H490,O00767,Q53GQ0,Q96RL7,Q9BU23,P16615,O00429,P01889,Q86UP2,Q96GC9,P35610,A1L0T0,P57088,Q9UBM7,Q8WXH0,Q96HY6,Q8TCJ2,Q14534,P04439,Q6IAN0,Q13190,Q9BUR5,Q8NFQ8,Q9Y678,Q9H0U3,Q9BVC6,P38435,O95674,O76024,Q8TD16,Q8N2K0,Q9Y320,Q6NUM9,Q8NBM4,Q6NUQ1,Q03001,P49755,Q8WVQ1,Q9H3N1,P27544,Q9BZF1,P37268,P10321,Q9NX47,Q9NTJ5,Q12981,P42345,P35606 Localization GO Cellular component msigdb_gocc 495,1,2,0,5,6,7,8,10,514,17,541,538,28,44,47,48,54,56,59,66,69,75,76,77,88,91,93,94,96,98,101,109,106,107,115,120,121,127,131,133,136,141,147,144,153,161,165,166,168,173,174,176,179,188,193,196,202,205,208,223,222,220,229,238,245,248,250,260,254,266,273,274,289,283,295,297,298,290,300,302,305,310,308,313,316,325,331,342,341,339,333,349,355,367,377,391,387,385,383,395,393,404,419,420,415,425,424,423,437,457,472,467,491,483,481,510,509,499,498,497 589,313,1111,106,300,2093,495,283,3347,1113,737,800,1390,1587,801,121,220,965,1588,2173,2478,196,2302,1526,144,1654,2544,514,2367,127,1168,393,636,1867,2023,967,1230,179,107,926,250,1170,1282,1171,395,892,968,2808,302,333,254,1173,637,3235,59,2177,2105,0,481,1118,222,290,1400,929,2314,2656,2,2029,467,2764,556,3150,2885,1,2491,2379,1798,497,308,165,483,383,1601,498,1602,17,188,1949,98,533,2435,572,897,437,812,193,273,88,1020,2723,1670,2258,2818,2896,1545,316,3286,3222,2845,1606,899,933,2259,1807,852,2196,1737,3155,1738,3322,3158,1810,3127,93,1240,854,423,1415,77,131,664,208,1744,1131,2613,499,355,821,1891,2126,5,822,2045,339,266,6,1025,1425,223,1817,2615,166,76,1556,1307,10,1247,69,173,94,248,295,7,1135,1428,1429,646,349,1313,415,424,600,1822,1029,141,153,622,305,56,174,2407,136,1758,830,47,419,48,1433,912,702,425,868,1367,377,538,1206,2830,44,1628,341,1826,202,404,832,1696,457,331,1317,245,1497,2410,1092,1566,274,578,1368,66,310,2739,342,91,101,238,297,628,176,3260,3109,2459,28,147,580,8,161,1509,2693,630,298,229,367,385,541,491,387,133,955,472,289,582,1216,1217,115,1218,96,682,509,510,796,2003,685,168,260,1155,1269,54,2468,325,766,2470,3229,1337,109,420,1585,75,3084,205,2474,120,391,1224 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3367 er 36 80 3.78748411878405 0.0001521804085957 Q07065,P04843,Q14739,O95674,P51572,Q96A33,O96005,Q8NHH9,P48651,O00767,Q9Y3E0,Q15125,P49755,P27824,Q96GC9,Q9P2W9,P46977,O15173,Q15392,Q06136,Q8TCJ2,Q9Y487,Q15041,Q5HYI8,Q16850,Q9NQC3,O15269,P48449,Q13190,Q9BZF1,Q96N66,O00264,Q9NTJ5,Q9Y5M8,O95470,Q12981 Localization OpenCell Localization opencell_localization 131,254,266,395,273,274,150,538,533,283,299,166,437,556,310,54,188,74,76,77,341,215,223,348,94,96,220,98,355,491,101,106,509,120,250,499 106,283,1113,74,220,965,2544,2367,1168,926,250,395,150,968,2808,254,1173,2177,2811,2813,556,1601,188,98,533,437,3152,273,2818,3222,2194,933,2196,3157,1240,574,77,131,2444,499,355,266,1425,223,166,76,1247,1310,94,348,1135,646,1822,2684,622,912,1367,538,1911,341,1762,1696,1566,274,2525,310,101,2459,2693,491,1218,96,795,509,1155,54,3317,299,215,120 2.333769977004763,1.1254866370979533,0.11801732694304702,2.9317872528718985,1.4644074828289309,0.1999552233330087,-0.5339391468977894,-0.43919996831517205,0.09036639678564706,0.22693649856222178,1.276921824455599,0.8299141117114622,1.9840930614703445,0.1999552233330087,-0.6964784202356398,1.2555985905367433,0.09036639678564706,-0.34644068419145774,-0.6964784202356398,-0.6964784202356398,0.5636060512556167,-0.10815269963874782,1.6443848730963768,2.4171181472402936,0.588482059091134,0.7348993205919421,-1.0406246148817728,1.1692778855749448,-0.6964784202356398,-1.1493154316371736,-0.34644068419145774,0.22693649856222178,-0.34644068419145774,-1.0406246148817728,0.06254274771127205,0.5385907773537494,2.8724277004854066,2.144806762718082,-0.4705554931571856,0.6378225083090472,0.9229538719151944,1.2126457954814382,-0.02198676428679048,1.4644074828289309,1.7985369233817154,2.8873405559171093,0.06254274771127205,0.034544176031171075,2.482708122078919,0.9459148854023514,0.11801732694304702,0.46269330605308917,-0.19602066046695343,-0.5982416058990344,0.488136037900703,0.2537554699892711,0.0063684354015670136,0.588482059091134,-0.22570012371921228,0.9687588066338071,-0.16653801380920247,-0.1372495529245524,-0.07924492702588042,1.1692778855749448,-0.5021341373910327,1.058987402257529,2.4171181472402936,-0.4705554931571856,-0.5982416058990344,0.6622900003005412,0.09036639678564706,2.433605013064534,0.3332580754721944,0.6378225083090472,0.11801732694304702,3.245078698171657,-1.5322507832020744,1.1034296234289172,1.525203768425511,2.2316801472635333 3367 Organelle subcompartment 138 348 3.722432178514047 0.0001973129180967 P09601,P30519,P24390,O00560,Q9UNK0,Q14108,Q14849,Q5BJF2,Q9BQE5,Q15629,P83436,O75352,P43307,Q9NPR9,Q99720,Q9Y5X1,Q8TB61,Q8N0U8,Q8N511,Q9P2W9,O00461,Q86XL3,P07099,Q96G23,Q15800,Q9Y3B3,Q15392,Q06136,P51648,P05067,Q96KC8,P67812,Q16850,Q9NQC3,P48449,Q96N66,Q9Y282,O00264,O95197,Q9HD20,P04062,Q9Y5M8,O15260,O75844,Q07065,Q9H1C4,Q8IV08,Q70UQ0,Q99735,O60725,Q86UE4,Q99996,Q9BRR6,P35613,Q15125,Q9NZ08,Q15904,Q86YN1,Q99442,O95070,P20645,P46977,P50402,O43752,O43852,Q8TCT9,Q9Y4P3,Q10472,P11717,Q15041,P16435,O15269,Q9BUN8,Q96PC5,O15127,Q92604,Q2TAA5,O95470,Q9P035,P04843,P50570,Q14739,P51572,Q96A33,Q08379,Q9H490,O00767,Q53GQ0,Q96RL7,Q9BU23,Q16706,P16615,O00429,P01889,Q86UP2,Q96GC9,P35610,A1L0T0,P57088,Q9UBM7,Q8WXH0,Q96HY6,Q8TCJ2,Q14534,P04439,Q6IAN0,Q4J6C6,Q12846,Q13190,Q9BUR5,Q96L58,Q8NFQ8,Q9Y678,Q9H0U3,Q9BVC6,P38435,Q10713,O95674,O76024,Q8N2K0,Q9Y320,Q6NUM9,Q8NBM4,Q6NUQ1,Q03001,P49755,Q8WVQ1,Q9H3N1,Q9P260,P27544,Q9BZF1,P37268,P10321,Q9NX47,Q9NTJ5,Q12981,P42345,P35606 Localization GO Cellular component msigdb_gocc 0,1,2,495,526,5,6,7,8,10,517,514,17,20,28,30,44,47,48,54,53,56,59,66,69,75,76,77,88,90,91,93,94,96,98,101,109,106,107,115,118,120,121,127,131,133,136,141,147,144,153,160,161,165,166,168,173,174,176,179,185,188,193,189,196,202,205,208,217,223,222,220,229,238,239,245,248,250,260,254,264,266,273,274,287,289,283,295,297,298,294,290,300,302,305,310,308,313,316,325,331,342,341,339,333,349,347,345,355,367,378,377,391,387,385,383,398,395,393,419,420,415,425,424,423,437,457,472,476,467,491,483,481,510,509,499,498,497 589,313,1111,106,300,735,53,2093,495,283,3064,3347,1113,653,737,800,1390,801,239,121,220,965,1588,2173,2478,1653,189,924,196,2302,1526,144,1654,691,2366,2544,514,2367,2098,127,1168,393,636,1867,2023,967,1230,179,107,926,250,1170,1282,1171,395,892,968,2808,302,118,333,254,1173,90,637,59,2177,2105,554,1594,0,2180,481,217,1118,222,290,1400,929,185,3012,2314,2656,2,2029,467,2764,556,2765,3150,2885,1,2491,2379,1798,497,308,165,483,383,1601,2319,498,17,2552,188,1949,98,533,2435,572,897,437,193,264,3152,273,88,1020,979,2437,2723,1670,2258,2818,2896,1544,1545,316,3286,3222,2845,1606,2324,899,933,2259,1807,852,2196,1737,1738,3322,3158,1810,3127,93,517,1240,817,574,1677,854,423,1415,77,131,2941,287,664,208,1743,398,1744,345,1131,2613,499,355,821,1891,2126,5,822,2045,339,266,782,6,2046,1025,1425,223,1817,2615,166,3277,76,1556,1307,10,1247,69,173,294,94,248,347,295,7,1135,1428,2134,1429,700,1897,646,349,1313,415,424,600,1822,1029,141,153,622,305,56,174,2407,136,943,1758,830,47,419,1627,48,1433,912,702,425,868,1367,377,538,1206,2830,44,1628,341,1826,202,832,1696,457,1763,331,1257,1317,245,1497,2410,1092,1566,274,578,1368,66,310,2739,342,91,378,2216,101,238,297,628,176,3260,3109,2459,28,147,580,3242,160,8,161,1509,2693,630,678,298,229,367,385,541,680,1837,491,2528,1571,2074,387,133,955,472,289,1214,582,1216,2151,1217,115,1218,20,96,2465,682,509,510,796,2003,685,168,260,1155,476,1269,54,2468,325,766,2470,769,2294,3229,526,1337,651,632,109,3144,3063,420,1585,2011,75,3084,205,120,30,391,1224,1934 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3367 Outer membrane 36 83 3.687915819628924 0.0002260984199227 P09601,Q9NS69,Q9BVC6,P21796,P45880,Q9Y277,Q9NZJ7,O60313,Q8N0X7,Q99720,Q6NUM9,Q96RL7,Q9Y512,O00429,Q9Y6C9,Q13505,P50402,Q8N2A8,P30536,Q9UBM7,Q9NX63,Q8WXH0,Q96TC7,O43169,Q8WY22,O96008,O75431,Q9BUR5,P50416,O00264,Q86UT6,Q16891,Q9NX47,Q5XKP0,Q13057,P42345 Localization GO Cellular component msigdb_gocc 0,3,385,13,19,548,276,279,418,28,415,297,565,300,306,58,193,194,191,325,461,331,343,79,80,466,97,367,485,106,504,363,510,502,500,498 106,300,3318,79,279,2302,2807,97,2649,1171,466,2808,3235,2245,0,2655,13,191,1798,3220,498,1602,19,193,485,1605,2895,3155,500,58,2049,3045,363,698,2510,502,415,1752,784,1976,2137,504,829,2573,2056,418,194,1433,1693,1694,331,80,1436,1320,297,343,675,1507,28,2631,367,385,1378,2794,1918,2697,920,650,3,1103,878,764,584,510,461,796,276,325,1048,548,3299,565,306 2.333769977004763,1.081263578277897,-1.5724386516725661,2.827392685729585,1.1474357022138544,-0.40806438662984673,-0.6964784202356398,2.4171181472402936,-0.5982416058990344,0.09036639678564706,0.6866243286062695,-0.6964784202356398,-1.1861480785988963,-0.37714563952921315,5.77073025593568,-0.5982416058990344,4.220028343416946,1.6247393272059847,-0.19602066046695343,-1.1493154316371736,0.6378225083090472,-0.10815269963874782,3.9215673900004977,1.6247393272059847,0.6622900003005412,-0.10815269963874782,-0.7632007073119792,-1.0406246148817728,0.6378225083090472,3.2036080031326675,-0.28566029525923553,-0.8997389788237078,0.8998745416649946,0.41136873678446767,-0.5021341373910327,0.6378225083090472,0.7826588994764823,-0.16653801380920247,0.3332580754721944,-0.25557908848123395,-0.31594654169938047,0.6378225083090472,0.30691434248850596,-0.5339391468977894,-0.28566029525923553,0.7826588994764823,1.6247393272059847,-0.02198676428679048,-0.1372495529245524,-0.1372495529245524,0.9914868411153721,2.797118956261447,-0.02198676428679048,0.034544176031171075,1.1034296234289172,0.9687588066338071,0.4371047742428398,-0.05052375805598644,3.665401627508389,-0.5659738392609449,0.8998745416649946,0.8533559354124849,0.0063684354015670136,-0.6634903102109926,-0.22570012371921228,-0.5982416058990344,0.2537554699892711,0.46269330605308917,4.832811783410612,0.14549770029311399,0.2804141068248859,0.3594471701790773,0.5385907773537494,0.6378225083090472,0.7108269558541094,0.3332580754721944,1.1692778855749448,1.014100175743301,0.17280963840827135,0.588482059091134,-1.45295805178107,0.5636060512556167,1.081263578277897 3367 Sphingolipid metabolic process 14 27 3.657988757384908 0.0002542021943636 O15269,Q96G23,P07602,P16278,O95470,P06280,P17900,Q06136,Q13510,P06865,P04062,P50897,Q9P035,Q8NCC3 Processes and pathways GO Biological process msigdb_gobp 220,66,65,41,250,139,169,77,78,81,118,26,260,63 220,965,250,118,139,81,65,1064,41,169,2314,467,1405,26,2396,77,519,78,698,63,66,379,796,685,276,260,1155 1.4644074828289309,0.1999552233330087,1.276921824455599,2.248856101291637,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,3.367269068562799,1.7413465847323417,-0.40806438662984673,0.6866243286062695,-0.02198676428679048,3.6904275097045454,-0.43919996831517205,2.8724277004854066,0.6132203653820887,2.8724277004854066,0.41136873678446767,3.1336381893089387,3.0911332595741183,0.8766756507402944,0.3332580754721944,0.4371047742428398,1.1692778855749448,1.2555985905367433,0.11801732694304702 3367 Cation transmembrane transporter activity 26 53 3.628846978087301 0.0002846899205903 Q99808,Q9H0U3,O43772,Q6P4Q7,P00403,Q70HW3,P24539,P13073,Q15043,Q9UDW1,P16615,O75964,O43808,P05141,P20020,P06576,Q9HC21,Q13423,P12235,Q9Y487,P30825,Q93050,P47985,Q9HD20,P25705,O95202 Functions GO Molecular function msigdb_gomf 259,387,134,400,145,22,411,167,293,40,290,45,549,553,436,435,324,71,447,215,89,92,484,115,244,123 134,549,1938,45,123,145,610,553,435,2370,1655,807,970,1872,447,167,290,436,1797,1537,2377,411,244,89,3038,2318,1539,2976,484,3321,2322,1073,1127,746,852,1548,71,293,906,400,22,1493,1038,92,259,387,2636,1002,324,115,40,585,215 2.1095839500852342,0.5636060512556167,-0.25557908848123395,3.286174597616811,2.19713106377011,2.002235460610414,0.488136037900703,0.5636060512556167,0.7348993205919421,-0.43919996831517205,-0.1372495529245524,0.30691434248850596,0.1999552233330087,-0.22570012371921228,0.7108269558541094,1.7795540517583925,1.1034296234289172,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,0.7826588994764823,1.3192668476331657,2.6583280208911844,-0.8997389788237078,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,0.6622900003005412,-1.5724386516725661,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,0.2804141068248859,-0.07924492702588042,2.9465065973455364,1.1034296234289172,0.2537554699892711,0.8299141117114622,3.8256681593087887,-0.05052375805598644,0.17280963840827135,2.5793442451134623,1.2555985905367433,0.8533559354124849,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,3.380645404831543,0.5385907773537494,1.525203768425511 3367 Mitochondrial transmembrane transport 21 45 3.6229871388554153 0.0002912203076574 O43772,O75746,O60830,O43615,Q99595,P21796,Q9UJS0,Q8IYU8,P24539,O95831,O75964,P06576,P12236,Q9H2D1,P12235,Q9BSK2,O96008,O14925,P50416,P25705,O95202 Processes and pathways GO Biological process msigdb_gobp 134,381,9,513,11,13,546,534,411,35,45,435,307,61,447,209,466,464,485,244,123 464,513,134,9,1015,2595,381,1938,45,2649,123,1456,35,466,553,435,3034,447,307,13,1347,411,244,2318,3321,485,1071,1073,1127,1548,826,534,1493,1826,1090,11,1376,209,61,2636,1002,2797,546,1579,734 0.6866243286062695,0.6132203653820887,2.1095839500852342,4.521067264147013,0.17280963840827135,-0.5659738392609449,0.8533559354124849,-0.25557908848123395,3.286174597616811,-0.5982416058990344,2.19713106377011,-0.05052375805598644,3.512290521765781,0.6866243286062695,0.5636060512556167,0.7348993205919421,-0.8997389788237078,0.7108269558541094,1.058987402257529,4.220028343416946,0.0063684354015670136,0.7826588994764823,1.3192668476331657,-0.40806438662984673,-1.5724386516725661,0.6622900003005412,0.14549770029311399,0.14549770029311399,0.11801732694304702,-0.07924492702588042,0.30691434248850596,0.588482059091134,-0.05052375805598644,-0.19602066046695343,0.14549770029311399,4.253245556056843,0.0063684354015670136,1.5652826911718993,3.161755509768943,-0.5659738392609449,0.1999552233330087,-0.6634903102109926,0.588482059091134,-0.07924492702588042,0.3854834577363446 3367 Receptor 10 28 3.6122699673333862 0.000303528325017 P20645,P11717,O75381,Q14108,Q9BUN8,Q567V2,Q9NR77,Q9UQB8,A6NIH7,Q8WTV0 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 185,217,319,5,229,82,214,86,57,60 57,1587,1588,1653,319,1281,1062,1531,217,185,2188,346,5,858,2273,82,1313,1899,1029,60,754,229,2076,1442,214,1782,1784,86 3.2036080031326675,-0.10815269963874782,-0.10815269963874782,-0.1372495529245524,1.014100175743301,0.034544176031171075,0.14549770029311399,-0.07924492702588042,1.5050295510613063,1.6639450277501382,-0.34644068419145774,0.9459148854023514,4.744465578955981,0.2804141068248859,-0.37714563952921315,2.766641730702969,0.034544176031171075,-0.22570012371921228,0.17280963840827135,3.1896999455248927,0.3594471701790773,1.4234149403548129,-0.28566029525923553,-0.02198676428679048,1.525203768425511,-0.16653801380920247,-0.16653801380920247,2.7050655515155833 3367 Inorganic molecular entity transmembrane transporter activity 26 57 3.586100317474279 0.0003356598777872 Q9H0U3,Q6P4Q7,P51798,P21796,Q9UBX3,P00403,Q9Y277,P45880,P24539,P13073,Q15043,Q9UDW1,P16615,O75964,P05141,P20020,P06576,Q13423,Q9C0H2,P12235,Q9Y487,Q93050,P47985,Q9HD20,P25705,O95202 Functions GO Molecular function msigdb_gomf 387,400,516,13,18,145,548,19,411,167,293,40,290,45,553,436,435,71,72,447,215,92,484,115,244,123 2645,738,1938,45,123,145,610,553,435,2370,1655,807,970,2180,1872,447,167,290,436,1797,1537,2377,13,411,244,3038,2318,1539,2976,19,484,3321,516,2322,1073,1127,746,852,1548,980,71,293,2340,400,1493,1038,92,72,387,2636,115,18,40,585,548,215,2536 -0.5982416058990344,0.3594471701790773,-0.25557908848123395,3.286174597616811,2.19713106377011,2.002235460610414,0.488136037900703,0.5636060512556167,0.7348993205919421,-0.43919996831517205,-0.1372495529245524,0.30691434248850596,0.1999552233330087,-0.34644068419145774,-0.22570012371921228,0.7108269558541094,1.7795540517583925,1.1034296234289172,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,4.220028343416946,0.7826588994764823,1.3192668476331657,-0.8997389788237078,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,3.9215673900004977,0.6622900003005412,-1.5724386516725661,0.6132203653820887,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,0.2804141068248859,-0.07924492702588042,0.1999552233330087,2.9465065973455364,1.1034296234289172,-0.40806438662984673,0.8299141117114622,-0.05052375805598644,0.17280963840827135,2.5793442451134623,2.9465065973455364,0.8533559354124849,-0.5659738392609449,2.283013353361886,4.015494309311654,3.380645404831543,0.5385907773537494,0.588482059091134,1.525203768425511,-0.5021341373910327 3367 Corneal opacity 23 58 3.5799986705970133 0.0003435959555337 O43933,P06280,O96028,P16278,Q03001,Q9NZC9,P52732,P04066,Q9UBM7,P10619,O43505,O75381,P56589,Q9Y4P3,Q13510,Q06136,P34913,Q9NVI7,P51648,Q16625,P04062,O95202,O75844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 132,139,401,41,423,444,304,184,325,190,195,319,449,205,78,77,207,475,88,242,118,123,127 480,1276,1114,195,1392,3116,2540,132,2753,2877,319,3169,127,1794,123,401,805,118,184,139,2375,190,41,1286,975,207,1661,2115,1541,88,304,1072,1470,449,1412,1677,423,77,1963,2566,78,858,1426,1614,2850,242,599,990,2279,1501,2418,475,2156,444,325,958,2296,205 0.6622900003005412,0.034544176031171075,0.11801732694304702,1.605007630123358,-0.02198676428679048,-1.004980242603473,-0.5339391468977894,2.12722970929693,-0.6634903102109926,-0.7632007073119792,1.014100175743301,-1.0765587039609845,2.16231565108635,-0.19602066046695343,2.19713106377011,0.8063488749900722,0.30691434248850596,2.248856101291637,1.6639450277501382,2.074084118777206,-0.43919996831517205,1.6247393272059847,3.367269068562799,0.034544176031171075,0.1999552233330087,1.5652826911718993,-0.1372495529245524,-0.31594654169938047,-0.07924492702588042,2.6739608306410108,1.081263578277897,0.14549770029311399,-0.05052375805598644,0.7108269558541094,-0.02198676428679048,-0.1372495529245524,0.7588428378146155,2.8724277004854066,-0.25557908848123395,-0.5339391468977894,2.8724277004854066,0.2804141068248859,-0.02198676428679048,-0.10815269963874782,-0.7297139540963061,1.3402905479186136,0.5134346459158582,0.1999552233330087,-0.37714563952921315,-0.05052375805598644,-0.43919996831517205,0.6866243286062695,-0.31594654169938047,0.7348993205919421,1.014100175743301,0.22693649856222178,-0.37714563952921315,1.5851890116525102 3367 Organic anion transport 21 39 3.564487961838519 0.0003645671820948 Q99808,O75746,Q13131,Q9UBX3,Q9NZJ7,Q9UJS0,O60831,Q8TB61,O43808,P05141,P12236,P41440,Q9H2D1,P07602,Q9HC21,P12235,P80404,P30825,Q15041,P53985,P28288 Processes and pathways GO Biological process msigdb_gobp 259,381,519,18,276,546,158,44,549,553,307,186,61,65,324,447,211,89,223,103,372 2363,549,158,381,1168,1456,2484,553,1531,65,807,692,447,307,893,372,89,186,1071,103,2322,211,980,519,223,1817,906,599,1822,44,259,61,2636,1002,324,276,18,2470,546 -0.43919996831517205,0.5636060512556167,1.9292237974120185,0.8533559354124849,0.09036639678564706,-0.05052375805598644,-0.5021341373910327,0.5636060512556167,-0.07924492702588042,3.0911332595741183,0.30691434248850596,0.41136873678446767,0.7108269558541094,1.058987402257529,0.2537554699892711,0.8766756507402944,2.6583280208911844,1.6639450277501382,0.14549770029311399,2.40057096317167,-0.40806438662984673,1.525203768425511,0.1999552233330087,0.6132203653820887,1.4644074828289309,-0.19602066046695343,0.2537554699892711,0.5134346459158582,-0.19602066046695343,3.34039786005235,1.2555985905367433,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,1.1692778855749448,4.015494309311654,-0.4705554931571856,0.588482059091134 3367 Transmembrane transport 80 187 3.5630056766785083 0.0003666327479807 Q9NS69,O60830,O43615,Q99595,P51798,P21796,Q15629,Q9UBX3,P45880,Q9Y277,Q70HW3,Q9UKG1,Q9UJS0,Q8IYU8,Q6NT16,O95831,Q9UHG3,Q9UDW1,Q8TB61,O75964,O43808,P05141,Q8IXU6,Q8WTV0,Q9H2D1,Q13423,Q9C0H2,P30825,P05067,P53985,P08183,Q9HD20,P04062,O95202,P27105,O75844,O43933,O43772,P00403,O60831,Q99996,P13073,Q99442,P41440,Q9BSK2,Q15041,Q16625,P25705,P31751,Q99808,P46934,P50570,Q96PU5,Q15043,P16615,Q96GC9,P12236,Q9HC21,P49840,O75381,Q8NE01,P42858,P28288,Q9H0U3,Q9BVC6,P38435,O75746,Q6P4Q7,P24539,P46939,O43707,P49755,P20020,P06576,P12235,O96008,O14925,Q9BZF1,P50416,P47985 Processes and pathways GO Biological process msigdb_gobp 3,9,513,11,516,13,10,18,19,548,22,547,546,534,32,35,37,40,44,45,549,553,52,60,61,71,72,89,90,103,110,115,118,123,124,127,132,134,145,158,160,167,176,186,209,223,242,244,257,259,262,264,268,293,290,310,307,324,320,319,351,344,372,387,385,383,381,400,411,413,410,437,436,435,447,466,464,491,485,484 1388,1855,2645,1389,2363,464,513,410,134,549,132,2303,9,158,1015,3008,2096,2807,319,2595,381,127,1168,1938,45,2649,123,1456,2426,35,466,145,118,610,90,553,1531,435,2370,2549,1655,110,807,970,2180,1872,3034,692,2599,1534,447,307,167,290,1181,436,1797,1537,2377,3012,13,1347,411,244,124,3070,612,372,3091,2491,89,257,3038,1798,3195,2318,1539,383,2976,186,344,19,262,413,484,3321,437,320,485,264,516,1605,1071,103,2608,1126,2322,1073,1127,3286,3222,2194,746,852,1808,3158,934,1548,980,1076,3276,1889,1890,1815,71,1304,1891,1554,2505,223,293,3277,10,906,1687,242,826,32,599,1822,400,1029,2512,22,2737,1758,52,534,1692,351,1493,44,1826,60,1090,1038,310,2739,268,176,3280,11,1507,259,160,1376,209,385,1839,491,72,387,61,2741,2636,1002,2797,324,115,1709,1710,3,1928,18,40,766,2162,37,585,546,1579,547,548,1521,2088,734,2536 -0.02198676428679048,-0.22570012371921228,-0.5982416058990344,-0.02198676428679048,-0.43919996831517205,0.6866243286062695,0.6132203653820887,0.7826588994764823,2.1095839500852342,0.5636060512556167,2.12722970929693,-0.40806438662984673,4.521067264147013,1.9292237974120185,0.17280963840827135,-0.8652075817496219,-0.31594654169938047,-0.6964784202356398,1.014100175743301,-0.5659738392609449,0.8533559354124849,2.16231565108635,0.09036639678564706,-0.25557908848123395,3.286174597616811,-0.5982416058990344,2.19713106377011,-0.05052375805598644,-0.4705554931571856,3.512290521765781,0.6866243286062695,2.002235460610414,2.248856101291637,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,0.7348993205919421,-0.43919996831517205,-0.5339391468977894,-0.1372495529245524,2.2999956417932186,0.30691434248850596,0.1999552233330087,-0.34644068419145774,-0.22570012371921228,-0.8997389788237078,0.41136873678446767,-0.5659738392609449,-0.07924492702588042,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,0.09036639678564706,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8652075817496219,4.220028343416946,0.0063684354015670136,0.7826588994764823,1.3192668476331657,2.19713106377011,-0.9345419567612725,0.488136037900703,0.8766756507402944,-0.969620885690122,-0.5021341373910327,2.6583280208911844,1.2555985905367433,-0.8997389788237078,-0.19602066046695343,-1.112787329154505,-0.40806438662984673,-0.07924492702588042,0.8533559354124849,-0.8309434988946349,1.6639450277501382,0.9459148854023514,3.9215673900004977,1.2341735778065615,0.7826588994764823,0.6622900003005412,-1.5724386516725661,0.7348993205919421,1.014100175743301,0.6622900003005412,1.2126457954814382,0.6132203653820887,-0.10815269963874782,0.14549770029311399,2.40057096317167,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,-1.37506621536203,-1.1493154316371736,-0.34644068419145774,0.3594471701790773,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,-0.07924492702588042,0.1999552233330087,0.14549770029311399,-1.3366301135330916,-0.22570012371921228,-0.22570012371921228,-0.19602066046695343,2.9465065973455364,0.034544176031171075,-0.22570012371921228,-0.07924492702588042,-0.5021341373910327,1.4644074828289309,1.1034296234289172,-1.3366301135330916,4.2752571823438945,0.2537554699892711,-0.1372495529245524,1.3402905479186136,0.30691434248850596,3.5639012562238195,0.5134346459158582,-0.19602066046695343,0.8299141117114622,0.17280963840827135,-0.5021341373910327,3.8256681593087887,-0.6307459142786708,-0.16653801380920247,3.258818635054596,0.588482059091134,-0.1372495529245524,0.9459148854023514,-0.05052375805598644,3.34039786005235,-0.19602066046695343,3.1896999455248927,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,1.722120594018782,-1.3366301135330916,4.253245556056843,-0.05052375805598644,1.2555985905367433,1.8736785287250628,0.0063684354015670136,1.5652826911718993,0.8533559354124849,-0.19602066046695343,0.6622900003005412,2.9465065973455364,0.8533559354124849,3.161755509768943,-0.6307459142786708,-0.5659738392609449,0.1999552233330087,-0.6634903102109926,1.014100175743301,2.283013353361886,-0.1372495529245524,-0.1372495529245524,4.832811783410612,-0.22570012371921228,4.015494309311654,3.380645404831543,0.3594471701790773,-0.31594654169938047,3.473195069920084,0.5385907773537494,0.588482059091134,-0.07924492702588042,0.588482059091134,0.588482059091134,-0.05052375805598644,-0.28566029525923553,0.3854834577363446,-0.5021341373910327 3367 Lipid localization 31 76 3.5613212420146336 0.0003689932894979 Q14108,O43772,Q14849,Q9BQE5,O95674,Q13131,Q9NZJ7,Q99720,P17900,O43808,Q9H6V9,Q96GC9,P35610,Q9H4L5,Q8WTV0,P30536,P07602,P61916,P35790,Q6IAA8,Q14534,Q9P260,O15118,Q9BZF1,Q9BUR5,P50416,P08183,P04062,O15260,P28288,P31751 Processes and pathways GO Biological process msigdb_gobp 5,134,6,8,395,519,276,28,169,549,50,310,308,582,60,191,65,197,201,598,339,476,85,491,367,485,110,118,121,372,257 589,3318,1390,85,121,134,549,1394,1862,1170,1171,395,968,2880,118,2484,2370,65,1064,2371,110,692,893,169,2314,2929,1347,372,1184,191,257,1798,308,201,2435,485,197,1547,1472,2396,3276,1476,519,5,339,6,2822,598,1822,828,3323,868,60,2143,310,1096,28,8,2693,367,1990,491,2220,761,582,50,2963,276,1155,476,711,769,1579,3165,1009,1224 0.5134346459158582,-1.5724386516725661,-0.02198676428679048,2.7359582136753127,2.214438638015626,2.1095839500852342,0.5636060512556167,-0.02198676428679048,-0.22570012371921228,0.09036639678564706,0.09036639678564706,0.8299141117114622,0.1999552233330087,-0.7632007073119792,2.248856101291637,-0.5021341373910327,-0.43919996831517205,3.0911332595741183,0.14549770029311399,-0.43919996831517205,2.2999956417932186,0.41136873678446767,0.2537554699892711,1.7413465847323417,-0.40806438662984673,-0.7969425638483784,0.0063684354015670136,0.8766756507402944,0.09036639678564706,1.6247393272059847,1.2555985905367433,-0.19602066046695343,1.058987402257529,1.5851890116525102,-0.4705554931571856,0.6622900003005412,1.605007630123358,-0.07924492702588042,-0.05052375805598644,-0.43919996831517205,-1.3366301135330916,-0.05052375805598644,0.6132203653820887,4.744465578955981,0.9687588066338071,4.664482621298005,-0.6964784202356398,0.5134346459158582,-0.19602066046695343,0.30691434248850596,-1.5724386516725661,0.2804141068248859,3.1896999455248927,-0.31594654169938047,1.058987402257529,0.14549770029311399,3.665401627508389,4.552178889851971,-0.5982416058990344,0.8998745416649946,-0.25557908848123395,0.6622900003005412,-0.34644068419145774,0.3594471701790773,0.5385907773537494,3.286174597616811,-0.7969425638483784,1.1692778855749448,0.11801732694304702,0.6866243286062695,0.41136873678446767,0.3594471701790773,-0.07924492702588042,-1.0406246148817728,0.1999552233330087,0.09036639678564706 3367 Transporter 72 171 3.5458088444473144 0.0003914100249171 O00560,Q99808,P24390,Q9UNK0,Q9H0U3,P11279,O43772,O75746,Q9BQE5,Q9BVK6,Q9UBX3,P51572,Q9NZJ7,Q92973,Q70HW3,Q9UJS0,Q9C0E2,Q08379,P24539,Q6NT16,Q9UPT5,Q15043,P16615,Q8TB61,P17900,O43808,P49755,P09496,P05141,Q8IXU6,Q9P2W9,Q9Y6C9,P20020,P12236,P06576,P41440,Q9UI12,Q9H2D1,O43752,Q9HC21,Q12768,P49257,O15400,P12235,Q9Y3B3,Q9BSK2,P13473,Q8TAG9,Q15833,Q9Y487,O43760,P30825,Q8TEX9,Q93050,O96008,O60749,Q12846,Q13190,Q92544,P53985,Q8N1F7,Q15075,Q15070,P08183,Q9HD45,Q99805,P25705,O95721,P28288,O95202,Q9Y678,P35606 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 495,259,2,526,387,261,134,381,8,541,18,273,276,405,22,546,407,287,411,32,429,293,290,44,169,549,437,554,553,52,54,306,436,307,435,186,585,61,189,324,321,572,446,447,75,209,210,212,501,215,216,89,469,92,466,465,345,355,489,103,233,361,360,110,112,379,244,247,372,123,391,497 1855,2171,887,495,888,3347,1452,1390,633,446,189,216,134,549,2095,1394,1936,465,691,1015,1592,381,1938,1230,123,926,1170,1282,1456,247,466,610,553,435,110,807,554,1594,692,261,447,307,210,290,169,436,1537,2377,2,411,244,372,2113,89,497,2318,2382,2976,186,1949,2435,572,437,273,1020,2557,1071,2723,1670,813,103,2258,1887,1126,1804,2322,2896,1073,1544,1127,614,746,852,1737,1956,1547,1548,817,574,980,287,1743,321,1077,345,1131,355,2042,2446,2128,2046,293,360,361,3277,906,501,2340,32,599,1822,22,909,828,52,233,1435,212,44,832,469,914,1762,1696,489,1980,405,92,1318,1567,2525,1209,2069,1375,379,259,8,3327,209,541,407,387,1921,61,2636,1002,324,112,1710,2639,1267,276,1155,2293,54,2468,2868,18,585,1578,546,526,651,429,3144,1050,75,215,2474,391,306 -0.22570012371921228,-0.34644068419145774,0.2537554699892711,0.6378225083090472,0.2537554699892711,-1.8215870556151397,-0.05052375805598644,-0.02198676428679048,0.46269330605308917,0.7108269558541094,1.6247393272059847,1.5050295510613063,2.1095839500852342,0.5636060512556167,-0.31594654169938047,-0.02198676428679048,-0.25557908848123395,0.6866243286062695,0.41136873678446767,0.17280963840827135,-0.10815269963874782,0.8533559354124849,-0.25557908848123395,0.06254274771127205,2.19713106377011,0.22693649856222178,0.09036639678564706,0.034544176031171075,-0.05052375805598644,1.2981442560194676,0.6866243286062695,0.488136037900703,0.5636060512556167,0.7348993205919421,2.2999956417932186,0.30691434248850596,0.5636060512556167,-0.10815269963874782,0.41136873678446767,1.2341735778065615,0.7108269558541094,1.058987402257529,1.5452878774447738,1.1034296234289172,1.7413465847323417,0.7348993205919421,-0.07924492702588042,-0.43919996831517205,5.106453588871854,0.7826588994764823,1.3192668476331657,0.8766756507402944,-0.31594654169938047,2.6583280208911844,0.6378225083090472,-0.40806438662984673,-0.43919996831517205,-0.8309434988946349,1.6639450277501382,-0.25557908848123395,-0.4705554931571856,0.5385907773537494,0.7348993205919421,1.1692778855749448,0.17280963840827135,-0.5339391468977894,0.14549770029311399,-0.6307459142786708,-0.1372495529245524,0.30691434248850596,2.40057096317167,-0.37714563952921315,-0.22570012371921228,0.11801732694304702,-0.19602066046695343,-0.40806438662984673,-0.7632007073119792,0.14549770029311399,-0.07924492702588042,0.11801732694304702,0.488136037900703,0.3594471701790773,0.2804141068248859,-0.16653801380920247,-0.25557908848123395,-0.07924492702588042,-0.07924492702588042,0.30691434248850596,0.5385907773537494,0.1999552233330087,1.1254866370979533,-0.16653801380920247,1.014100175743301,0.14549770029311399,0.9459148854023514,0.11801732694304702,0.9229538719151944,-0.28566029525923553,-0.4705554931571856,-0.31594654169938047,-0.28566029525923553,1.1034296234289172,0.8998745416649946,0.8998745416649946,-1.3366301135330916,0.2537554699892711,0.6378225083090472,-0.40806438662984673,3.5639012562238195,0.5134346459158582,-0.19602066046695343,3.8256681593087887,0.2537554699892711,0.30691434248850596,3.258818635054596,1.402777585756001,-0.02198676428679048,1.525203768425511,3.34039786005235,0.30691434248850596,0.6866243286062695,0.2537554699892711,-0.16653801380920247,-0.1372495529245524,0.6622900003005412,-0.25557908848123395,0.8063488749900722,2.5793442451134623,0.034544176031171075,-0.07924492702588042,-0.5021341373910327,0.09036639678564706,-0.28566029525923553,0.0063684354015670136,0.8766756507402944,1.2555985905367433,4.552178889851971,-1.5724386516725661,1.5652826911718993,0.588482059091134,0.8063488749900722,0.8533559354124849,-0.22570012371921228,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.2999956417932186,-0.1372495529245524,-0.5659738392609449,0.06254274771127205,1.1692778855749448,0.11801732694304702,-0.37714563952921315,3.245078698171657,-0.4705554931571856,-0.7297139540963061,4.015494309311654,0.5385907773537494,-0.07924492702588042,0.588482059091134,0.6132203653820887,0.46269330605308917,0.7588428378146155,-1.004980242603473,0.17280963840827135,2.9317872528718985,1.525203768425511,-0.4705554931571856,0.8533559354124849,1.081263578277897 3367 Sphingolipid metabolism 13 25 3.540971109030365 0.0003986572282941 O15269,P10619,P07602,Q96G23,P16278,P06280,P17900,Q06136,Q13510,P06865,P04062,P51648,O95470 Processes and pathways Reactome Pathways msigdb_reactome 220,190,65,66,41,139,169,77,78,81,118,88,250 589,220,965,738,926,250,118,139,81,65,1064,190,555,41,169,2314,467,88,77,78,66,2693,796,276,1155 0.5134346459158582,1.4644074828289309,0.1999552233330087,0.3594471701790773,0.22693649856222178,1.276921824455599,2.248856101291637,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,1.6247393272059847,0.5636060512556167,3.367269068562799,1.7413465847323417,-0.40806438662984673,0.6866243286062695,2.6739608306410108,2.8724277004854066,2.8724277004854066,3.0911332595741183,-0.5982416058990344,0.3332580754721944,1.1692778855749448,0.11801732694304702 3367 Ion transmembrane transport 53 135 3.5364986818879047 0.0004054685245347 Q9H0U3,Q9BVC6,O43772,P46934,P50570,O75746,Q6P4Q7,P51798,P21796,Q96PU5,Q9UBX3,P45880,Q9Y277,P00403,Q70HW3,Q9UJS0,Q8IYU8,O60831,Q99996,P24539,P46939,O43707,Q9UHG3,P13073,Q9UDW1,Q15043,P16615,Q8TB61,O75964,O43808,P05141,Q96GC9,P20020,P06576,P12236,P41440,Q9H2D1,Q9HC21,Q13423,Q9C0H2,P12235,P30825,P05067,Q15041,P42858,P53985,P47985,P08183,Q9HD20,P25705,O95202,P27105,O75844 Processes and pathways GO Biological process msigdb_gobp 387,385,134,262,264,381,400,516,13,268,18,19,548,145,22,546,534,158,160,411,413,410,37,167,40,293,290,44,45,549,553,310,436,435,307,186,61,324,71,72,447,89,90,223,344,103,484,110,115,244,123,124,127 2645,1389,2363,410,134,549,2303,158,1015,3008,2096,2807,2595,381,127,1168,1938,45,123,1456,2426,145,610,90,553,1531,435,2370,2549,1655,110,807,970,2180,1872,1534,447,307,167,290,1181,436,1797,1537,2377,3012,13,411,244,124,3070,612,3091,2491,89,3038,3195,2318,1539,2976,186,344,19,262,413,484,3321,264,516,1071,103,2608,1126,2322,1073,1127,746,852,1808,3158,934,1548,980,1076,1889,1890,1815,71,1304,1891,1554,2505,223,293,3277,906,400,1029,22,1758,534,1692,1493,44,1090,1038,310,2739,268,3280,1507,160,1376,385,72,387,61,2741,2636,1002,324,115,1709,18,40,2162,37,585,546,1579,548,1521,2088,734,2536 -0.5982416058990344,-0.02198676428679048,-0.43919996831517205,0.7826588994764823,2.1095839500852342,0.5636060512556167,-0.40806438662984673,1.9292237974120185,0.17280963840827135,-0.8652075817496219,-0.31594654169938047,-0.6964784202356398,-0.5659738392609449,0.8533559354124849,2.16231565108635,0.09036639678564706,-0.25557908848123395,3.286174597616811,2.19713106377011,-0.05052375805598644,-0.4705554931571856,2.002235460610414,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,0.7348993205919421,-0.43919996831517205,-0.5339391468977894,-0.1372495529245524,2.2999956417932186,0.30691434248850596,0.1999552233330087,-0.34644068419145774,-0.22570012371921228,-0.07924492702588042,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,0.09036639678564706,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8652075817496219,4.220028343416946,0.7826588994764823,1.3192668476331657,2.19713106377011,-0.9345419567612725,0.488136037900703,-0.969620885690122,-0.5021341373910327,2.6583280208911844,-0.8997389788237078,-1.112787329154505,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,1.6639450277501382,0.9459148854023514,3.9215673900004977,1.2341735778065615,0.7826588994764823,0.6622900003005412,-1.5724386516725661,1.2126457954814382,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,-0.07924492702588042,0.1999552233330087,0.14549770029311399,-0.22570012371921228,-0.22570012371921228,-0.19602066046695343,2.9465065973455364,0.034544176031171075,-0.22570012371921228,-0.07924492702588042,-0.5021341373910327,1.4644074828289309,1.1034296234289172,-1.3366301135330916,0.2537554699892711,0.8299141117114622,0.17280963840827135,3.8256681593087887,-0.16653801380920247,0.588482059091134,-0.1372495529245524,-0.05052375805598644,3.34039786005235,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,-1.3366301135330916,-0.05052375805598644,1.8736785287250628,0.0063684354015670136,0.8533559354124849,2.9465065973455364,0.8533559354124849,3.161755509768943,-0.6307459142786708,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,-0.1372495529245524,4.015494309311654,3.380645404831543,-0.31594654169938047,3.473195069920084,0.5385907773537494,0.588482059091134,-0.07924492702588042,0.588482059091134,-0.05052375805598644,-0.28566029525923553,0.3854834577363446,-0.5021341373910327 3367 Coated vesicle 20 83 3.5279839727624043 0.0004187375094595 P24390,Q14108,P50570,Q5VW38,P51572,Q08379,Q9Y5X1,P42892,P01889,Q8N511,O95070,P20645,O43752,P02786,Q9Y3B3,P04439,P11717,P05067,Q13190,Q9Y282 Localization GO Cellular component msigdb_gocc 2,5,264,16,273,287,30,43,302,48,179,185,189,200,75,333,217,90,355,109 2171,1225,735,3347,801,1653,189,3282,691,2544,2367,1281,1230,179,1170,1282,1062,302,200,333,90,554,1594,481,3034,1940,217,773,185,2,497,43,1949,572,437,264,3152,273,2723,1670,1125,813,2258,2896,2324,2259,1737,1956,817,1677,287,1131,1078,355,2042,5,2202,1360,1556,1307,16,700,48,1318,835,541,1837,1921,1572,1709,795,2001,2293,2468,2469,2748,2294,1520,109,75,30,391,1586 -0.34644068419145774,0.06254274771127205,0.3594471701790773,-1.8215870556151397,0.30691434248850596,-0.1372495529245524,1.6247393272059847,-1.37506621536203,0.41136873678446767,-0.5339391468977894,-0.43919996831517205,0.034544176031171075,0.06254274771127205,1.7028121530513547,0.09036639678564706,0.034544176031171075,0.14549770029311399,1.081263578277897,1.5851890116525102,0.9687588066338071,2.595251590463738,0.5636060512556167,-0.10815269963874782,0.6622900003005412,-0.8997389788237078,-0.25557908848123395,1.5050295510613063,0.3332580754721944,1.6639450277501382,5.106453588871854,0.6378225083090472,3.34039786005235,-0.25557908848123395,0.5385907773537494,0.7348993205919421,1.2126457954814382,-1.0406246148817728,1.1692778855749448,-0.6307459142786708,-0.1372495529245524,0.11801732694304702,0.30691434248850596,-0.37714563952921315,-0.7632007073119792,-0.40806438662984673,-0.37714563952921315,-0.16653801380920247,-0.25557908848123395,0.30691434248850596,-0.1372495529245524,1.1254866370979533,0.11801732694304702,0.14549770029311399,0.9229538719151944,-0.28566029525923553,4.744465578955981,-0.34644068419145774,0.0063684354015670136,-0.07924492702588042,0.034544176031171075,4.130251742479455,0.41136873678446767,3.286174597616811,0.034544176031171075,0.30691434248850596,0.588482059091134,-0.19602066046695343,-0.22570012371921228,-0.07924492702588042,-0.1372495529245524,0.3332580754721944,-0.25557908848123395,-0.37714563952921315,-0.4705554931571856,-0.4705554931571856,-0.6307459142786708,-0.37714563952921315,-0.05052375805598644,2.333769977004763,2.9317872528718985,3.614933961940769,0.8533559354124849,-0.07924492702588042 3367 Hydrolase activity hydrolyzing o glycosyl compounds 13 23 3.4793342850871825 0.0005026611417418 P10253,P16278,P06280,P17900,O60476,P06865,P54802,P04062,P04066,Q9BTY2,O00462,Q9NUJ1,O60502 Functions GO Molecular function msigdb_gomf 163,41,139,169,235,81,83,118,184,249,126,155,62 126,480,235,62,118,184,139,81,1064,163,41,169,1662,83,1416,2126,1746,294,2138,249,155,3083,2643 2.1797569087503486,0.6622900003005412,1.3820450016487578,3.1336381893089387,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,0.14549770029311399,1.8362643641609107,3.367269068562799,1.7413465847323417,-0.1372495529245524,2.7513259355917703,-0.02198676428679048,-0.31594654169938047,-0.16653801380920247,1.1034296234289172,-0.31594654169938047,1.2981442560194676,1.9658773878837006,-0.9345419567612725,-0.5659738392609449 3367 Mitochondrial transport 33 77 3.4774047796656617 0.000506292846099 Q9NS69,Q14849,O43772,O60830,O43615,Q99595,Q10713,Q13131,P51572,Q9UBX3,P45880,Q9UJS0,O14737,P24539,O95831,Q9Y512,O75964,P05141,P06576,P30536,Q96EK5,P49840,P49257,P12235,P55786,O96008,O14925,O75431,Q9P0J0,P50416,Q15070,P25705,Q5JRX3 Processes and pathways GO Biological process msigdb_gobp 3,6,134,9,513,11,398,519,273,18,19,546,284,411,35,565,45,553,435,191,323,320,572,447,84,466,464,97,230,485,360,244,375 1854,284,464,513,134,9,97,2595,1938,45,2649,3254,2305,2369,35,466,928,553,435,969,2245,3034,447,2759,1347,411,244,3091,1234,191,2432,2318,2932,19,3321,1666,572,320,1467,485,273,1605,84,1073,1127,2846,398,519,6,360,3045,826,698,375,599,2344,2573,2056,1090,323,1209,1506,11,3056,2797,1710,3,230,2746,18,546,1579,733,3299,1386,565,1853 -0.22570012371921228,1.1254866370979533,0.6866243286062695,0.6132203653820887,2.1095839500852342,4.521067264147013,2.4171181472402936,-0.5659738392609449,-0.25557908848123395,3.286174597616811,-0.5982416058990344,-1.2607479309781038,-0.40806438662984673,-0.43919996831517205,3.512290521765781,0.6866243286062695,0.22693649856222178,0.5636060512556167,0.7348993205919421,0.1999552233330087,-0.37714563952921315,-0.8997389788237078,0.7108269558541094,-0.6634903102109926,0.0063684354015670136,0.7826588994764823,1.3192668476331657,-0.969620885690122,0.06254274771127205,1.6247393272059847,-0.4705554931571856,-0.40806438662984673,-0.7969425638483784,3.9215673900004977,-1.5724386516725661,-0.1372495529245524,0.5385907773537494,1.014100175743301,-0.05052375805598644,0.6622900003005412,1.1692778855749448,-0.10815269963874782,2.7513259355917703,0.14549770029311399,0.11801732694304702,-0.7297139540963061,0.8299141117114622,0.6132203653820887,4.664482621298005,0.8998745416649946,-0.8997389788237078,0.30691434248850596,0.41136873678446767,0.8766756507402944,0.5134346459158582,-0.40806438662984673,-0.5339391468977894,-0.28566029525923553,0.14549770029311399,1.014100175743301,0.09036639678564706,-0.05052375805598644,4.253245556056843,-0.8997389788237078,-0.6634903102109926,-0.1372495529245524,4.832811783410612,1.4234149403548129,-0.6307459142786708,4.015494309311654,0.588482059091134,-0.07924492702588042,0.3854834577363446,-1.45295805178107,0.0063684354015670136,0.5636060512556167,-0.19602066046695343 3367 Protein localization 34 69 3.465147032988531 0.0005299416611943 P09601,Q9NS69,O43933,O75746,O60830,O43615,Q99595,Q10713,P21796,O15254,Q9UJS0,P46379,Q9Y512,Q2T9J0,P06576,P12236,Q13505,P50402,Q9NX63,O75381,P12235,P56589,P34913,Q9NR77,P51648,P05067,O96008,O14925,O75431,Q13190,Q15067,P25705,P28288,Q5JRX3 Processes and pathways Reactome Pathways msigdb_reactome 0,3,132,381,9,513,11,398,13,149,546,29,565,439,435,307,58,193,461,319,447,449,207,214,88,90,466,464,97,355,232,244,372,375 713,2708,464,1390,771,149,513,738,1055,549,132,9,319,3168,97,2595,3314,381,3145,2649,2102,466,90,435,970,3033,0,3034,447,307,2109,13,2929,244,372,207,3176,3220,29,193,88,1292,449,3286,3222,398,2672,355,58,232,439,826,375,719,1694,1983,11,2862,2797,214,3,461,1155,2747,546,733,2008,565,1853 0.3854834577363446,-0.6307459142786708,0.6866243286062695,-0.02198676428679048,0.3332580754721944,1.9840930614703445,0.6132203653820887,0.3594471701790773,0.14549770029311399,0.5636060512556167,2.12722970929693,4.521067264147013,1.014100175743301,-1.0765587039609845,2.4171181472402936,-0.5659738392609449,-1.5322507832020744,0.8533559354124849,-1.0406246148817728,-0.5982416058990344,-0.31594654169938047,0.6866243286062695,2.595251590463738,0.7348993205919421,0.1999552233330087,-0.8997389788237078,5.77073025593568,-0.8997389788237078,0.7108269558541094,1.058987402257529,-0.31594654169938047,4.220028343416946,-0.7969425638483784,1.3192668476331657,0.8766756507402944,1.5652826911718993,-1.0765587039609845,-1.1493154316371736,3.614933961940769,1.6247393272059847,2.6739608306410108,0.034544176031171075,0.7108269558541094,-1.37506621536203,-1.1493154316371736,0.8299141117114622,-0.5982416058990344,0.9229538719151944,3.2036080031326675,1.402777585756001,0.7348993205919421,0.30691434248850596,0.8766756507402944,0.3854834577363446,-0.1372495529245524,-0.25557908848123395,4.253245556056843,-0.7297139540963061,-0.6634903102109926,1.525203768425511,4.832811783410612,0.7108269558541094,0.11801732694304702,-0.6307459142786708,0.588482059091134,0.3854834577363446,-0.25557908848123395,0.5636060512556167,-0.19602066046695343 3367 Mental deterioration 33 100 3.4634871331443997 0.0005332220961729 Q14108,Q9BQE5,P21964,Q10713,O76024,P00403,Q9NZJ7,O60313,Q9NPL8,P50897,Q96RL7,P16278,P17900,O00429,P35637,P07602,P61916,Q13510,P06865,P54802,O15118,Q9Y487,Q14203,P05067,P27544,O96008,P42858,O75503,P20700,Q5XKP0,P04062,Q96F07,O95470 Drugs and Diseases Human Phenotype Ontology msigdb_hp 5,8,396,398,393,145,276,279,154,26,297,41,169,300,192,65,197,78,81,83,85,215,468,90,467,466,344,102,359,502,118,506,250 300,85,738,654,279,3007,1527,1057,102,393,250,466,145,118,3283,1283,90,81,65,1064,2372,2178,1657,2810,1176,555,41,808,169,1286,359,2430,396,1017,2027,467,2604,2930,192,1539,2976,1602,344,1461,1186,2555,26,2661,2037,83,1470,2818,197,1673,817,2265,1416,1191,981,1889,2499,398,500,2501,1553,78,5,468,2675,1894,502,3129,1253,1753,1976,830,1433,539,1501,2411,506,1209,297,1094,3280,3026,8,2791,154,650,1517,2865,276,686,1519,3312,1386,2966,215,2967 1.081263578277897,2.7359582136753127,0.3594471701790773,0.4371047742428398,1.1474357022138544,-0.8652075817496219,-0.07924492702588042,0.14549770029311399,2.40057096317167,0.8299141117114622,1.276921824455599,0.6866243286062695,2.002235460610414,2.248856101291637,-1.37506621536203,0.034544176031171075,2.595251590463738,2.781905953857426,3.0911332595741183,0.14549770029311399,-0.43919996831517205,-0.34644068419145774,-0.1372495529245524,-0.6964784202356398,0.09036639678564706,0.5636060512556167,3.367269068562799,0.30691434248850596,1.7413465847323417,0.034544176031171075,0.8998745416649946,-0.4705554931571856,0.8299141117114622,0.17280963840827135,-0.28566029525923553,0.6866243286062695,-0.5659738392609449,-0.7969425638483784,1.6247393272059847,-0.07924492702588042,-0.8309434988946349,-0.10815269963874782,0.9459148854023514,-0.05052375805598644,0.09036639678564706,-0.5339391468977894,3.6904275097045454,-0.5982416058990344,-0.28566029525923553,2.7513259355917703,-0.05052375805598644,-0.6964784202356398,1.605007630123358,-0.1372495529245524,0.30691434248850596,-0.37714563952921315,-0.02198676428679048,0.09036639678564706,0.1999552233330087,-0.22570012371921228,-0.5021341373910327,0.8299141117114622,0.6378225083090472,-0.5021341373910327,-0.07924492702588042,2.8724277004854066,4.744465578955981,0.6866243286062695,-0.5982416058990344,-0.22570012371921228,0.6378225083090472,-1.004980242603473,0.06254274771127205,-0.16653801380920247,-0.25557908848123395,0.30691434248850596,-0.02198676428679048,0.588482059091134,-0.05052375805598644,-0.43919996831517205,0.6378225083090472,0.09036639678564706,1.1034296234289172,0.14549770029311399,-1.3366301135330916,-0.8652075817496219,4.552178889851971,-0.6634903102109926,1.9658773878837006,0.46269330605308917,-0.05052375805598644,-0.7297139540963061,1.1692778855749448,0.4371047742428398,-0.05052375805598644,-1.4924261166507573,0.0063684354015670136,-0.7969425638483784,1.525203768425511,-0.7969425638483784 3367 Glycoside hydrolase superfamily [IPR017853] 9 16 3.4619373851601907 0.000536301910335 P10253,P16278,P06280,P06865,P54802,P04062,P04066,O00462,O60502 Sequence InterPro Superfamily interpro_homologous_superfamily 163,41,139,81,83,118,184,126,62 126,62,118,184,139,81,1064,807,163,41,1662,83,1416,1746,249,680 2.1797569087503486,3.1336381893089387,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,0.14549770029311399,0.30691434248850596,1.8362643641609107,3.367269068562799,-0.1372495529245524,2.7513259355917703,-0.02198676428679048,-0.16653801380920247,1.2981442560194676,0.4371047742428398 3367 Azurophil granule membrane 11 22 3.429460493348888 0.0006047824709005 P07602,P10253,Q07065,P11279,Q92542,P13473,P42785,O95721,O15260,P27105,O00462 Localization GO Cellular component msigdb_gocc 65,163,131,261,227,210,21,247,121,124,126 126,121,1227,1527,247,65,163,261,210,124,1601,21,977,131,598,1367,227,2064,2692,387,276,1155 2.1797569087503486,2.214438638015626,0.06254274771127205,-0.07924492702588042,1.2981442560194676,3.0911332595741183,1.8362643641609107,1.2341735778065615,1.5452878774447738,2.19713106377011,-0.10815269963874782,3.8498324746709085,0.1999552233330087,2.144806762718082,0.5134346459158582,0.0063684354015670136,1.443957948969997,-0.28566029525923553,-0.5982416058990344,0.8533559354124849,1.1692778855749448,0.11801732694304702 3367 Anion transmembrane transporter activity 20 37 3.424930256660892 0.0006149572623335 Q99808,O75746,P51798,P21796,Q9UBX3,P45880,Q9Y277,Q9UJS0,Q15043,Q8TB61,O43808,P05141,P12236,P41440,Q9H2D1,Q9HC21,Q9C0H2,P12235,P30825,P53985 Functions GO Molecular function msigdb_gomf 259,381,516,13,18,19,548,546,293,44,549,553,307,186,61,324,72,447,89,103 2645,2363,738,549,381,1456,553,807,2180,692,447,307,13,89,186,19,516,1071,103,2322,980,293,906,2340,599,1822,44,259,72,61,2636,1002,324,18,546,548,2536 -0.5982416058990344,-0.43919996831517205,0.3594471701790773,0.5636060512556167,0.8533559354124849,-0.05052375805598644,0.5636060512556167,0.30691434248850596,-0.34644068419145774,0.41136873678446767,0.7108269558541094,1.058987402257529,4.220028343416946,2.6583280208911844,1.6639450277501382,3.9215673900004977,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.40806438662984673,0.1999552233330087,1.1034296234289172,0.2537554699892711,-0.40806438662984673,0.5134346459158582,-0.19602066046695343,3.34039786005235,1.2555985905367433,2.9465065973455364,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,4.015494309311654,0.588482059091134,0.588482059091134,-0.5021341373910327 3367 Endoplasmic reticulum golgi intermediate compartment 16 45 3.4158675649818044 0.0006357915975323 P24390,Q13190,Q9Y3B3,Q9Y282,Q15904,P49755,P80303,Q02818,P51572,Q8N511,Q96GC9,Q10472,O95070,O15260,Q08379,Q9Y678 Localization GO Cellular component msigdb_gocc 2,355,75,109,173,437,15,46,273,48,310,208,179,121,287,391 445,121,1524,1588,2367,179,1345,1656,2,2764,639,572,437,2321,273,2723,1125,1021,15,46,287,208,1131,355,782,2615,173,700,1904,48,1257,2907,3337,310,1509,541,1839,1006,2468,2162,1160,109,75,391,1586 0.7108269558541094,2.214438638015626,-0.07924492702588042,-0.10815269963874782,-0.43919996831517205,1.7028121530513547,0.0063684354015670136,-0.1372495529245524,5.106453588871854,-0.6634903102109926,0.46269330605308917,0.5385907773537494,0.7348993205919421,-0.40806438662984673,1.1692778855749448,-0.6307459142786708,0.11801732694304702,0.17280963840827135,4.164124775027304,3.286174597616811,1.1254866370979533,1.5652826911718993,0.11801732694304702,0.9229538719151944,0.3332580754721944,-0.5659738392609449,1.722120594018782,0.41136873678446767,-0.22570012371921228,3.286174597616811,0.06254274771127205,-0.7632007073119792,-1.6539313317624937,1.058987402257529,-0.05052375805598644,0.588482059091134,-0.19602066046695343,0.1999552233330087,-0.4705554931571856,-0.31594654169938047,0.11801732694304702,2.333769977004763,2.9317872528718985,0.8533559354124849,-0.07924492702588042 3367 Glycoprotein biosynthetic process 22 50 3.4088218094418368 0.0006524408146471 Q9H0U3,P04843,P83436,Q6ZXV5,Q7LGA3,Q08379,Q16706,Q86YN1,P35610,P46977,Q86SF2,O60502,Q8WVQ1,O43505,Q10472,Q8TCJ2,O15118,Q92542,O60476,Q99805,Q96L58,Q2TAA5 Processes and pathways GO Biological process msigdb_gobp 387,254,517,267,152,287,294,174,308,188,317,62,457,195,208,341,85,227,235,379,378,248 2093,2708,85,2018,195,235,62,1526,2594,1654,2544,514,2368,254,1173,742,308,1601,188,2196,517,854,2442,287,664,208,2126,822,294,248,267,152,1624,317,174,341,457,227,2348,378,379,630,387,1440,1214,922,1006,2162,712,1934 -0.31594654169938047,-0.6307459142786708,2.7359582136753127,-0.28566029525923553,1.605007630123358,1.3820450016487578,3.1336381893089387,-0.07924492702588042,-0.5659738392609449,-0.1372495529245524,-0.5339391468977894,0.6132203653820887,-0.43919996831517205,1.2555985905367433,0.09036639678564706,0.3594471701790773,1.058987402257529,-0.10815269963874782,1.6443848730963768,-0.34644068419145774,0.6132203653820887,0.2804141068248859,-0.4705554931571856,1.1254866370979533,0.4371047742428398,1.5652826911718993,-0.31594654169938047,0.30691434248850596,1.1034296234289172,1.2981442560194676,1.2126457954814382,1.9840930614703445,-0.10815269963874782,1.0365999791862452,1.722120594018782,0.9687588066338071,0.7108269558541094,1.443957948969997,-0.40806438662984673,0.8766756507402944,0.8766756507402944,0.488136037900703,0.8533559354124849,-0.02198676428679048,0.09036639678564706,0.2537554699892711,0.1999552233330087,-0.31594654169938047,0.41136873678446767,-0.22570012371921228 3367 Transporters 146 338 3.404747416771587 0.0006622527767112 O00560,P24390,Q9UH99,Q14108,Q14849,Q5BJF2,Q15629,P51798,Q5VW38,Q9UBX3,P45880,Q70HW3,Q9UJS0,Q8NHH9,Q99720,Q8IYU8,O60637,Q6NT16,P12270,Q9Y512,Q8TB61,O43808,Q8N511,P09496,P05141,Q8IXU6,Q8WTV0,Q9H2D1,Q9UI12,Q9BTX1,P07602,Q96AG4,P49257,Q9C0H2,Q9Y3B3,Q641Q2,Q8WY22,O15118,Q6NUK1,Q15287,P30825,P05067,O60826,Q93050,A0FGR8,Q96N66,P53985,P08183,P05023,Q9HD20,P33176,P57740,O15260,O95202,P27105,Q9NQZ5,O75844,Q6DD88,Q658P3,Q07065,O43933,Q9H1C4,O43772,P06493,Q9BRK5,P00403,O96005,O60831,O75955,P35613,P13073,Q15904,Q99442,P20645,P41440,P46977,O43752,P61916,Q6UW68,P02786,Q9BSK2,P13473,Q8TAG9,Q9NR77,P11717,Q2M389,Q9BUN8,Q8N1F7,Q96PC5,O15127,Q16625,O15397,Q99808,P04843,P11279,P46934,P50570,Q6ZXV5,P51572,Q96A33,Q9NZJ7,O60313,Q96RL7,Q15043,P16615,O00429,Q9Y6C9,Q96GC9,P12236,P57088,Q9HC21,O75381,Q8TCJ2,P04439,Q8NE01,Q12846,Q13190,Q9BUR5,Q15070,Q16891,Q99805,O00410,P28288,Q9H0U3,Q9BVC6,O75746,Q6P4Q7,O76024,Q92973,Q9C0E2,Q9Y320,Q8IY95,Q9UPT5,P49755,P20020,P12235,O15258,P56589,Q9H3N1,Q9ULH0,Q8TEX9,O96008,Q9UPN3,Q9BZF1,Q92544,P50416 Functions Protein Atlas Protein class protein_atlas_protein_class 495,2,525,5,6,7,10,516,16,18,19,22,546,538,28,534,31,32,531,565,44,549,48,554,553,52,60,61,585,64,65,578,572,72,75,577,80,85,599,597,89,90,593,92,589,101,103,110,610,115,613,614,121,123,124,650,127,646,129,131,132,133,134,637,148,145,150,158,162,165,167,173,176,185,186,188,189,197,198,200,209,210,212,214,217,225,229,233,238,239,242,246,259,254,261,262,264,267,273,274,276,279,297,293,290,300,306,310,307,316,324,319,341,333,351,345,355,367,360,363,379,370,372,387,385,381,400,393,405,407,420,417,429,437,436,447,445,449,472,477,469,466,494,491,489,485 589,1275,2645,370,2804,300,887,495,1717,888,2363,1648,653,1390,1587,85,239,445,121,633,246,1588,1652,738,1653,189,134,549,132,279,1787,3282,31,2095,1936,1013,593,158,1015,2544,2877,319,1592,1721,381,127,1168,162,393,2547,1059,2023,1281,1230,123,926,891,2970,927,2481,1456,1062,150,466,145,2880,200,3283,2484,333,928,254,1173,610,90,553,1531,637,2370,65,1655,110,807,1065,554,1594,1872,692,1658,261,217,447,307,531,167,210,2312,2376,290,1596,436,185,1797,1537,2377,3012,2430,2,124,372,89,2604,613,165,716,1539,2931,2382,2976,2252,1601,186,19,2384,2552,262,188,572,897,437,2190,812,485,264,976,1019,273,516,1020,2557,1070,1071,813,103,1887,1126,2322,780,2818,2896,449,316,614,3286,3222,2194,1294,746,852,2196,197,1809,3157,3158,1956,2394,3127,2938,2667,1297,1958,1548,817,980,1549,131,819,1476,1814,1743,1077,1744,2397,345,355,821,2127,5,858,2848,2202,6,2046,1425,3224,293,360,597,10,906,173,749,242,363,225,7,1135,1428,1895,16,577,129,646,2340,32,1313,599,1822,400,198,267,22,909,829,52,417,1825,911,534,233,48,912,351,1565,868,2951,1435,913,538,212,2830,44,341,2785,832,469,60,722,80,1142,489,669,2410,405,92,1566,274,578,835,1567,310,2739,1701,3346,101,1145,238,1209,297,176,1375,28,379,259,1376,148,2693,209,64,229,367,385,2415,2072,1837,491,407,72,387,133,61,2075,472,1215,2636,1002,2076,324,1217,115,1709,650,214,2352,1710,682,1926,2003,276,1155,2868,1222,18,2590,766,525,1106,585,2163,1578,546,2998,1580,2701,477,494,429,733,420,3299,75,1164,2089,565,1647,2834,2536,306 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3367 Ion transport 21 43 3.4042303288944287 0.000663507794012 Q658P3,Q9BVC6,Q6P4Q7,P51798,P21796,P45880,Q9Y277,P24539,Q15043,P16615,Q15904,O75964,P20020,P06576,Q9C0H2,Q9Y487,Q8NE01,O96008,Q93050,P25705,O95202 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 129,385,400,516,13,19,548,411,293,290,173,45,436,435,72,215,351,466,92,244,123 2645,1938,45,123,466,610,435,2180,290,436,1537,2377,13,411,244,2318,1539,2976,19,3321,516,1126,2322,1073,1127,746,2505,293,173,129,2340,400,351,1493,92,1376,385,72,1213,585,548,215,2536 -0.5982416058990344,-0.25557908848123395,3.286174597616811,2.19713106377011,0.6866243286062695,0.488136037900703,0.7348993205919421,-0.34644068419145774,1.1034296234289172,0.7348993205919421,-0.07924492702588042,-0.43919996831517205,4.220028343416946,0.7826588994764823,1.3192668476331657,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,3.9215673900004977,-1.5724386516725661,0.6132203653820887,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,-0.5021341373910327,1.1034296234289172,1.722120594018782,2.16231565108635,-0.40806438662984673,0.8299141117114622,0.9459148854023514,-0.05052375805598644,2.5793442451134623,0.0063684354015670136,0.8533559354124849,2.9465065973455364,0.09036639678564706,0.5385907773537494,0.588482059091134,1.525203768425511,-0.5021341373910327 3367 Glycosidase 11 19 3.399681384329971 0.0006746441654716 P10253,P16278,P06280,O60476,P06865,P54802,P04062,P04066,Q9BTY2,O00462,O60502 Functions Protein Atlas Molecular function protein_atlas_molecular_function 163,41,139,235,81,83,118,184,249,126,62 126,480,2174,235,62,118,184,139,81,1064,163,41,1662,83,2395,2126,1746,294,249 2.1797569087503486,0.6622900003005412,-0.34644068419145774,1.3820450016487578,3.1336381893089387,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,0.14549770029311399,1.8362643641609107,3.367269068562799,-0.1372495529245524,2.7513259355917703,-0.43919996831517205,-0.31594654169938047,-0.16653801380920247,1.1034296234289172,1.2981442560194676 3367 Secretory granule membrane 23 63 3.381047977053325 0.0007220993350922 P30519,Q9H0U3,Q07065,P11279,Q9NZJ7,P42785,P10253,P35613,P49755,P01889,P07602,Q14254,P13473,P11717,Q93050,Q5T9A4,Q92542,O00264,P10321,O95721,O15260,P27105,O00462 Localization GO Cellular component msigdb_gocc 1,387,131,261,276,21,163,165,437,302,65,338,210,217,92,487,227,106,481,247,121,124,126 106,126,1390,121,2303,2095,1227,1527,2098,1281,247,302,65,163,481,261,217,210,3355,772,929,124,1,2491,2840,165,1601,21,779,437,977,1019,2723,933,2259,2325,1810,3178,1240,131,695,2611,1242,822,338,2508,487,598,1976,1367,1206,227,92,2064,2692,1837,387,1218,276,1155,2470,527,2475 2.333769977004763,2.1797569087503486,-0.02198676428679048,2.214438638015626,-0.40806438662984673,-0.31594654169938047,0.06254274771127205,-0.07924492702588042,-0.31594654169938047,0.034544176031171075,1.2981442560194676,1.081263578277897,3.0911332595741183,1.8362643641609107,0.6622900003005412,1.2341735778065615,1.5050295510613063,1.5452878774447738,-1.9957969029261853,0.3332580754721944,0.22693649856222178,2.19713106377011,5.215090048676801,-0.5021341373910327,-0.7297139540963061,1.7985369233817154,-0.10815269963874782,3.8498324746709085,0.3332580754721944,0.7348993205919421,0.1999552233330087,0.17280963840827135,-0.6307459142786708,0.22693649856222178,-0.37714563952921315,-0.40806438662984673,-0.19602066046695343,-1.0765587039609845,0.06254274771127205,2.144806762718082,0.41136873678446767,-0.5659738392609449,0.06254274771127205,0.30691434248850596,0.9687588066338071,-0.5021341373910327,0.6622900003005412,0.5134346459158582,-0.25557908848123395,0.0063684354015670136,0.09036639678564706,1.443957948969997,2.5793442451134623,-0.28566029525923553,-0.5982416058990344,-0.19602066046695343,0.8533559354124849,0.09036639678564706,1.1692778855749448,0.11801732694304702,-0.4705554931571856,0.6132203653820887,-0.4705554931571856 3367 Endoplasmic reticulum 82 189 3.3769303488318205 0.0007329960867024 Q14849,Q5BJF2,Q92791,O75352,P43307,Q8NHH9,Q9H3G5,P48651,Q8WUJ1,Q8N0U8,P27824,Q13217,Q9P2W9,Q86XL3,Q99943,Q96G23,Q96AG4,Q15800,P49257,Q00765,O43169,Q6NUQ4,P51648,O60826,Q96KC8,Q16850,Q9NQC3,Q9BT22,O00264,O95197,O15260,Q6DD88,Q8IV08,O94874,O60879,P30533,Q70UQ0,Q99735,O96005,Q14257,Q9NZ01,Q9UBS4,Q86UE4,O60831,Q15125,Q99442,Q9Y680,P50402,O43852,Q6UW68,P35790,Q8TCT9,Q15041,O15269,Q9BUN8,Q96KA5,Q96PC5,O95470,Q9P035,P04843,P51572,Q96A33,O00767,Q15043,P13674,Q86UP2,Q96GC9,P35610,Q9UBM7,Q96HY6,Q8TCJ2,Q5HYI8,P21964,O95674,P67809,Q9H3N1,P27544,P37268,Q9Y3U8,Q96F07,Q12981,P35606 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 6,7,12,514,17,538,27,533,42,47,556,558,54,56,580,66,578,69,572,574,79,600,88,593,91,94,96,630,106,107,121,646,136,636,634,639,141,147,150,151,685,687,153,158,166,176,178,193,196,198,201,202,223,220,229,237,238,250,260,254,273,274,283,293,303,305,310,308,325,342,341,348,396,395,414,472,467,483,512,506,499,497 106,283,800,801,121,220,3065,79,2478,196,593,158,634,514,1168,636,2023,107,926,250,395,150,2808,254,1173,3301,1531,1345,1723,2310,2180,2106,1941,303,972,1118,2313,1400,1231,2246,1232,3264,396,3036,1459,1945,467,1233,2764,556,2974,2885,639,2888,497,308,201,1237,483,1601,1123,17,1947,1881,1665,1462,1464,1290,533,1732,572,193,2321,2660,273,88,1805,3222,2979,2438,2439,851,852,2196,2664,1954,3017,2665,1295,1738,2393,2609,1410,2261,2560,1350,1190,2122,2610,2124,2326,1239,2772,414,1351,935,574,2396,1475,1744,499,1193,558,1964,2126,151,2045,1746,6,223,293,2615,166,1361,1247,69,94,2571,7,348,646,600,1623,198,141,153,305,56,136,830,47,1433,2783,1367,538,1206,341,202,995,42,1317,12,274,578,673,1368,506,66,310,342,237,91,238,176,147,580,874,2693,630,229,1843,27,472,1217,96,795,2001,2003,685,260,1155,1269,54,325,687,1712,766,512,178 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3367 Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 10 31 3.3519290635112777 0.0008025057843439 P09601,P30519,O00767,Q6UW02,Q15800,Q32P28,P13674,Q9BU89,Q16850,P16435 Functions GO Molecular function msigdb_gomf 0,1,283,226,69,140,303,157,94,222 2093,283,3065,890,1526,2098,892,1345,0,303,222,1184,1,1799,814,854,1744,339,69,94,140,1899,1751,647,226,1754,157,2220,2078,2424,2015 -0.31594654169938047,1.1254866370979533,-0.9345419567612725,0.2537554699892711,-0.07924492702588042,-0.31594654169938047,0.2537554699892711,0.0063684354015670136,5.77073025593568,1.081263578277897,1.4644074828289309,0.09036639678564706,5.215090048676801,-0.19602066046695343,0.30691434248850596,0.2804141068248859,-0.16653801380920247,0.9687588066338071,2.9611783576004687,2.482708122078919,2.0383028111640002,-0.22570012371921228,-0.16653801380920247,0.46269330605308917,1.443957948969997,-0.16653801380920247,1.9475878367392199,-0.34644068419145774,-0.28566029525923553,-0.43919996831517205,-0.25557908848123395 3367 Organic acid transport 16 40 3.327336123793067 0.0008768054341075 O43772,O75746,P53985,P50416,P08183,Q13131,P28288,Q9UBX3,Q9UJS0,P80404,P30825,P41440,Q15041,Q9H2D1,O60831,P31751 Processes and pathways GO Biological process msigdb_gobp 134,381,103,485,110,519,372,18,546,211,89,186,223,61,158,257 2363,1390,134,549,158,381,1168,1456,1171,2880,2484,1531,2371,110,807,692,893,1347,372,1184,89,257,1798,186,485,1071,103,2322,211,980,519,223,1817,906,1822,61,2636,1002,18,546 -0.43919996831517205,-0.02198676428679048,2.1095839500852342,0.5636060512556167,1.9292237974120185,0.8533559354124849,0.09036639678564706,-0.05052375805598644,0.09036639678564706,-0.7632007073119792,-0.5021341373910327,-0.07924492702588042,-0.43919996831517205,2.2999956417932186,0.30691434248850596,0.41136873678446767,0.2537554699892711,0.0063684354015670136,0.8766756507402944,0.09036639678564706,2.6583280208911844,1.2555985905367433,-0.19602066046695343,1.6639450277501382,0.6622900003005412,0.14549770029311399,2.40057096317167,-0.40806438662984673,1.525203768425511,0.1999552233330087,0.6132203653820887,1.4644074828289309,-0.19602066046695343,0.2537554699892711,-0.19602066046695343,3.161755509768943,-0.5659738392609449,0.1999552233330087,4.015494309311654,0.588482059091134 3367 Vacuole 73 209 3.317921317403579 0.0009069002761461 O00560,P15586,Q9Y2Q5,Q9UNK0,Q07065,Q14108,Q14849,Q5BJF2,Q9H1C4,Q8IV08,Q15165,P06280,P11279,Q9NX40,Q9UM22,Q9P2J5,O14964,Q9NZJ7,P42785,Q9H0U3,P50897,Q8IY95,P42345,P38435,O75955,P10253,Q96RL7,Q9UHG3,Q15043,P16278,P42892,P17900,Q8N511,Q8NHP8,Q96GC9,P04066,P20645,P41440,Q8WTV0,Q8NCC3,Q92820,P10619,P07602,Q9H7Z7,P61916,O14773,O15400,Q13510,P06865,P13473,P54802,O15118,Q9Y487,Q93050,O60749,Q12846,P42858,Q92542,Q9BTY2,O75503,Q9UIQ6,Q9H0B6,P11117,O00754,Q16625,O00584,Q99538,P04062,O95721,O15260,Q15833,P27105,O00462 Localization GO Cellular component msigdb_gocc 495,128,527,526,131,5,6,7,133,136,135,139,261,271,14,272,392,276,21,387,26,417,498,383,162,163,297,37,293,41,43,169,48,49,310,184,185,186,60,63,322,190,65,67,197,70,446,78,81,210,83,85,215,92,465,345,344,227,249,102,105,368,108,480,242,116,507,118,247,121,501,124,126 2171,126,495,116,480,1452,70,392,85,121,633,446,3005,3115,738,1653,690,465,1227,1527,1592,102,162,1281,247,1062,3032,2808,118,184,1173,139,81,2370,2549,2025,65,1064,969,1655,807,1065,2105,554,2179,163,190,108,1940,1873,261,210,555,128,41,1346,169,1182,185,2111,1537,2377,2656,124,3070,2764,2431,2186,715,1235,613,1539,383,3354,2976,1601,186,498,21,344,43,2721,2552,1800,641,2436,1124,26,2606,976,977,1019,516,1886,1125,813,1021,83,2818,2896,1544,2845,1606,2259,2391,746,197,3157,1956,2125,1740,1129,817,1354,1961,1677,981,2396,131,1476,1890,1743,345,1815,558,1553,78,2446,2043,5,1892,6,293,135,501,242,699,7,598,136,417,48,2783,63,1367,1089,49,703,1911,60,1762,1763,227,322,92,1318,2064,1368,835,1567,2525,310,1209,297,998,675,507,1210,2788,2692,678,249,680,1837,1571,368,387,133,1921,1572,67,3209,1709,682,2963,271,2157,3060,276,1155,2293,272,880,37,585,105,2296,14,1520,3165,526,2702,527,844,3299,215,1163,2835,1224 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3367 Glycosylation 17 45 3.30050874005803 0.0009650970756123 O43505,P04843,O75503,Q16706,Q6ZXV5,O60476,Q86YN1,Q10472,Q8TCJ2,O15118,Q96L58,P04062,Q2TAA5,Q08379,P46977,Q86SF2,O60502 Processes and pathways GO Biological process msigdb_gobp 195,254,102,294,267,235,174,208,341,85,378,118,248,287,188,317,62 2093,85,2018,195,235,62,1526,1654,2544,514,102,2368,118,254,1173,1601,188,2196,517,854,2442,287,664,208,2126,822,294,248,267,1624,317,174,341,378,2216,630,387,1440,3082,1006,2162,632,3063,712,1934 -0.31594654169938047,2.7359582136753127,-0.28566029525923553,1.605007630123358,1.3820450016487578,3.1336381893089387,-0.07924492702588042,-0.1372495529245524,-0.5339391468977894,0.6132203653820887,2.40057096317167,-0.43919996831517205,2.248856101291637,1.2555985905367433,0.09036639678564706,-0.10815269963874782,1.6443848730963768,-0.34644068419145774,0.6132203653820887,0.2804141068248859,-0.4705554931571856,1.1254866370979533,0.4371047742428398,1.5652826911718993,-0.31594654169938047,0.30691434248850596,1.1034296234289172,1.2981442560194676,1.2126457954814382,-0.10815269963874782,1.0365999791862452,1.722120594018782,0.9687588066338071,0.8766756507402944,-0.34644068419145774,0.488136037900703,0.8533559354124849,-0.02198676428679048,-0.9345419567612725,0.1999552233330087,-0.31594654169938047,0.488136037900703,-0.8997389788237078,0.41136873678446767,-0.22570012371921228 3367 Organic acid transmembrane transport 13 26 3.2956147685576647 0.000982065805932 O43772,O75746,P53985,P50416,P08183,P28288,Q9UBX3,P30825,P41440,Q15041,Q9H2D1,O60831,P31751 Processes and pathways GO Biological process msigdb_gobp 134,381,103,485,110,372,18,89,186,223,61,158,257 134,158,381,1168,1456,1531,110,807,692,1347,372,89,257,1798,186,485,1071,103,980,223,906,61,2636,1002,18,546 2.1095839500852342,1.9292237974120185,0.8533559354124849,0.09036639678564706,-0.05052375805598644,-0.07924492702588042,2.2999956417932186,0.30691434248850596,0.41136873678446767,0.0063684354015670136,0.8766756507402944,2.6583280208911844,1.2555985905367433,-0.19602066046695343,1.6639450277501382,0.6622900003005412,0.14549770029311399,2.40057096317167,0.1999552233330087,1.4644074828289309,0.2537554699892711,3.161755509768943,-0.5659738392609449,0.1999552233330087,4.015494309311654,0.588482059091134 3367 Hydrolase activity acting on glycosyl bonds 14 33 3.2941359608561007 0.0009872473295409 P10253,O75503,P16278,P06280,P17900,O60476,P06865,P54802,P04062,P04066,Q9BTY2,O00462,Q9NUJ1,O60502 Functions GO Molecular function msigdb_gomf 163,102,41,139,169,235,81,83,118,184,249,126,155,62 126,480,2174,235,62,102,118,184,139,81,1064,163,2108,1178,41,169,1459,3070,2766,1662,83,2395,1416,2126,1746,294,1752,2138,3357,249,155,3083,2643 2.1797569087503486,0.6622900003005412,-0.34644068419145774,1.3820450016487578,3.1336381893089387,2.40057096317167,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,0.14549770029311399,1.8362643641609107,-0.31594654169938047,0.09036639678564706,3.367269068562799,1.7413465847323417,-0.05052375805598644,-0.9345419567612725,-0.6634903102109926,-0.1372495529245524,2.7513259355917703,-0.43919996831517205,-0.02198676428679048,-0.31594654169938047,-0.16653801380920247,1.1034296234289172,-0.16653801380920247,-0.31594654169938047,-2.085389547406722,1.2981442560194676,1.9658773878837006,-0.9345419567612725,-0.5659738392609449 3367 Glycoprotein metabolic process 24 57 3.283307034867256 0.0010259685672122 Q9H0U3,P04843,P83436,Q6ZXV5,Q7LGA3,Q08379,Q16706,Q86YN1,P35610,P46977,Q86SF2,O60502,Q8WVQ1,O43505,Q10472,Q8TCJ2,O15118,Q92542,O60476,O00754,Q99805,Q96L58,Q2TAA5,O00462 Processes and pathways GO Biological process msigdb_gobp 387,254,517,267,152,287,294,174,308,188,317,62,457,195,208,341,85,227,235,480,379,378,248,126 126,2093,480,2708,85,2018,195,235,62,1526,2594,1654,2544,514,2368,254,1173,972,742,308,1601,188,2196,2560,517,854,2442,287,664,208,2126,822,1746,294,248,267,152,1624,317,174,341,457,227,2348,378,3280,379,1509,630,387,1440,1214,922,1006,2162,712,1934 2.1797569087503486,-0.31594654169938047,0.6622900003005412,-0.6307459142786708,2.7359582136753127,-0.28566029525923553,1.605007630123358,1.3820450016487578,3.1336381893089387,-0.07924492702588042,-0.5659738392609449,-0.1372495529245524,-0.5339391468977894,0.6132203653820887,-0.43919996831517205,1.2555985905367433,0.09036639678564706,0.1999552233330087,0.3594471701790773,1.058987402257529,-0.10815269963874782,1.6443848730963768,-0.34644068419145774,-0.5339391468977894,0.6132203653820887,0.2804141068248859,-0.4705554931571856,1.1254866370979533,0.4371047742428398,1.5652826911718993,-0.31594654169938047,0.30691434248850596,-0.16653801380920247,1.1034296234289172,1.2981442560194676,1.2126457954814382,1.9840930614703445,-0.10815269963874782,1.0365999791862452,1.722120594018782,0.9687588066338071,0.7108269558541094,1.443957948969997,-0.40806438662984673,0.8766756507402944,-1.3366301135330916,0.8766756507402944,-0.05052375805598644,0.488136037900703,0.8533559354124849,-0.02198676428679048,0.09036639678564706,0.2537554699892711,0.1999552233330087,-0.31594654169938047,0.41136873678446767,-0.22570012371921228 3367 Transport of small molecules 50 138 3.263066270456647 0.0011021374421527 P09601,P30519,Q658P3,Q99808,Q9H0U3,P51798,P21796,Q96PU5,Q10713,Q9UBX3,P45880,Q9Y277,Q70HW3,Q8IYU8,O43242,P28070,P35613,Q9BU23,Q15043,P20618,P28072,Q8TB61,Q15904,P16615,P09496,P05141,P20020,P35610,P12236,Q8WTV0,P61916,Q9C0H2,P02786,P12235,P56589,O15118,Q9Y487,P30825,O00231,Q93050,Q9BUN8,P53985,P49721,Q9UEY8,P08183,Q9HD20,P28074,P28288,O95202,P27105 Processes and pathways Reactome Pathways msigdb_reactome 0,1,129,259,387,516,13,268,398,18,19,548,22,534,528,36,165,298,293,291,170,44,173,290,554,553,436,308,307,60,197,72,200,447,449,85,215,89,463,92,229,103,104,369,110,115,119,372,123,124 463,3001,2094,2921,85,528,1015,2595,2836,3253,2023,1281,123,1062,200,610,553,1174,1345,110,807,554,0,1176,692,447,307,1796,290,1399,436,1232,291,1537,2377,774,13,3172,2761,2883,3257,124,3303,36,170,119,372,1,2491,89,2031,308,1730,2841,165,3092,2251,1539,3354,2976,3123,19,1950,2036,104,978,516,813,103,1126,2322,2558,2818,449,2038,1074,746,197,2039,2937,3040,3157,1956,1411,1472,817,2443,398,1744,1079,1304,821,1891,2778,2270,2048,293,906,173,129,1822,22,2209,534,1565,1493,44,60,1090,1436,92,835,268,648,1772,998,1507,259,1376,298,229,72,387,2741,2636,115,1710,18,369,2470,585,1579,923,2164,688,548,215,734 0.6866243286062695,-0.8652075817496219,-0.31594654169938047,-0.7969425638483784,2.7359582136753127,0.588482059091134,0.17280963840827135,-0.5659738392609449,-0.7297139540963061,-1.2607479309781038,-0.28566029525923553,0.034544176031171075,2.19713106377011,0.14549770029311399,1.5851890116525102,0.488136037900703,0.5636060512556167,0.09036639678564706,0.0063684354015670136,2.2999956417932186,0.30691434248850596,0.5636060512556167,5.77073025593568,0.09036639678564706,0.41136873678446767,0.7108269558541094,1.058987402257529,-0.19602066046695343,1.1034296234289172,-0.02198676428679048,0.7348993205919421,0.06254274771127205,1.1034296234289172,-0.07924492702588042,-0.43919996831517205,0.3332580754721944,4.220028343416946,-1.0765587039609845,-0.6634903102109926,-0.7632007073119792,-1.2607479309781038,2.19713106377011,-1.4924261166507573,3.473195069920084,1.7413465847323417,2.2316801472635333,0.8766756507402944,5.215090048676801,-0.5021341373910327,2.6583280208911844,-0.28566029525923553,1.058987402257529,-0.16653801380920247,-0.7297139540963061,1.7985369233817154,-0.969620885690122,-0.37714563952921315,-0.07924492702588042,-1.951622338591048,-0.8309434988946349,-1.004980242603473,3.9215673900004977,-0.25557908848123395,-0.28566029525923553,2.36729383704207,0.1999552233330087,0.6132203653820887,0.30691434248850596,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.5339391468977894,-0.6964784202356398,0.7108269558541094,-0.28566029525923553,0.14549770029311399,0.3594471701790773,1.605007630123358,-0.28566029525923553,-0.7969425638483784,-0.8997389788237078,-1.0406246148817728,-0.25557908848123395,-0.02198676428679048,-0.05052375805598644,0.30691434248850596,-0.4705554931571856,0.8299141117114622,-0.16653801380920247,0.14549770029311399,0.034544176031171075,0.30691434248850596,-0.22570012371921228,-0.6634903102109926,-0.37714563952921315,-0.28566029525923553,1.1034296234289172,0.2537554699892711,1.722120594018782,2.16231565108635,-0.19602066046695343,3.8256681593087887,-0.34644068419145774,0.588482059091134,-0.07924492702588042,-0.05052375805598644,3.34039786005235,3.1896999455248927,0.14549770029311399,-0.02198676428679048,2.5793442451134623,0.30691434248850596,1.2126457954814382,0.46269330605308917,-0.16653801380920247,0.1999552233330087,-0.05052375805598644,1.2555985905367433,0.0063684354015670136,1.1034296234289172,1.4234149403548129,2.9465065973455364,0.8533559354124849,-0.6307459142786708,-0.5659738392609449,2.283013353361886,-0.1372495529245524,4.015494309311654,0.8998745416649946,-0.4705554931571856,0.5385907773537494,-0.07924492702588042,0.2537554699892711,-0.31594654169938047,0.4371047742428398,0.588482059091134,1.525203768425511,0.3854834577363446 3367 transporter 19 57 3.2493649413989267 0.0011566298748004 Q99808,O43772,O60830,Q99595,Q92973,Q9C0E2,P41440,Q9H2D1,Q567V2,Q9NR77,Q8TEX9,Q92544,Q8N1F7,P53985,Q15070,Q9HD45,Q99805,O15397,O00410 Functions Panther Protein class panther_protein_class 259,134,9,11,405,407,186,61,82,214,469,489,233,103,360,112,379,246,370 370,888,1452,1587,633,246,513,738,134,1936,9,1721,927,716,2382,186,2435,2190,1020,2557,1070,1071,103,1887,780,2896,614,852,1547,1077,2046,360,82,2340,909,233,1435,832,469,489,405,1567,1145,1375,11,379,259,3327,407,61,2076,112,214,2163,1578,1579,2474 0.8766756507402944,0.2537554699892711,-0.05052375805598644,-0.10815269963874782,0.46269330605308917,1.2981442560194676,0.6132203653820887,0.3594471701790773,2.1095839500852342,-0.25557908848123395,4.521067264147013,-0.16653801380920247,0.22693649856222178,0.3854834577363446,-0.43919996831517205,1.6639450277501382,-0.4705554931571856,-0.34644068419145774,0.17280963840827135,-0.5339391468977894,0.14549770029311399,0.14549770029311399,2.40057096317167,-0.22570012371921228,0.3332580754721944,-0.7632007073119792,0.488136037900703,0.2804141068248859,-0.07924492702588042,0.14549770029311399,-0.28566029525923553,0.8998745416649946,2.766641730702969,-0.40806438662984673,0.2537554699892711,1.402777585756001,-0.02198676428679048,0.30691434248850596,0.6866243286062695,0.6622900003005412,0.8063488749900722,-0.07924492702588042,0.11801732694304702,0.0063684354015670136,4.253245556056843,0.8766756507402944,1.2555985905367433,-1.5724386516725661,0.8063488749900722,3.161755509768943,-0.28566029525923553,2.2999956417932186,1.525203768425511,-0.31594654169938047,-0.07924492702588042,-0.07924492702588042,-0.4705554931571856 3367 Hexosyltransferase activity 11 32 3.239424855627522 0.0011977102149212 O43505,P04843,Q6ZXV5,Q10472,Q8TCJ2,P06865,P04062,Q2TAA5,P46977,Q86SF2,Q13126 Functions GO Molecular function msigdb_gomf 195,254,267,208,341,81,118,248,188,317,95 2093,2018,195,1526,1654,2544,118,254,1173,1117,81,1064,1873,1179,1662,1800,188,854,1416,664,208,95,248,267,1624,317,2346,341,378,630,1440,1006 -0.31594654169938047,-0.28566029525923553,1.605007630123358,-0.07924492702588042,-0.1372495529245524,-0.5339391468977894,2.248856101291637,1.2555985905367433,0.09036639678564706,0.11801732694304702,2.781905953857426,0.14549770029311399,-0.22570012371921228,0.09036639678564706,-0.1372495529245524,-0.19602066046695343,1.6443848730963768,0.2804141068248859,-0.02198676428679048,0.4371047742428398,1.5652826911718993,2.4663995632740083,1.2981442560194676,1.2126457954814382,-0.10815269963874782,1.0365999791862452,-0.40806438662984673,0.9687588066338071,0.8766756507402944,0.488136037900703,-0.02198676428679048,0.1999552233330087 3367 Steroid binding 9 22 3.2374677108926084 0.001205955857751 P30536,Q14108,Q14849,O15173,O00264,P21796,P45880,O15118,P04062 Functions GO Molecular function msigdb_gomf 191,5,6,74,106,13,19,85,118 106,85,74,2023,118,610,1655,13,2314,2929,191,308,383,19,197,5,6,1096,1990,491,761,582 2.333769977004763,2.7359582136753127,2.9317872528718985,-0.28566029525923553,2.248856101291637,0.488136037900703,-0.1372495529245524,4.220028343416946,-0.40806438662984673,-0.7969425638483784,1.6247393272059847,1.058987402257529,0.8533559354124849,3.9215673900004977,1.605007630123358,4.744465578955981,4.664482621298005,0.14549770029311399,-0.25557908848123395,0.6622900003005412,0.3594471701790773,0.5385907773537494 3367 Golgi membrane 45 122 3.234915964416169 0.0012167853774276 Q6ZRP7,P24390,Q14108,Q9H1C4,Q8IV08,Q92896,P50570,P42345,P83436,Q10713,P51572,Q7LGA3,Q08379,Q9Y3E0,P35613,Q16706,Q8TB61,P01889,P49755,Q9P2W9,O00461,O95070,Q86SF2,O43752,Q9H7Z7,O43505,Q9Y3B3,Q15392,O15258,Q10472,P04439,P11717,Q13190,Q8IZA0,Q9BUR5,Q9Y282,O60476,O95197,P10321,Q9NTJ5,Q96L58,O95721,O15260,Q9Y678,P35606 Localization GO Cellular component msigdb_gocc 258,2,5,133,136,137,264,498,517,398,273,152,287,299,165,294,44,302,437,54,53,179,317,189,67,195,75,76,445,208,333,217,355,100,367,109,235,107,481,509,378,247,121,391,497 1388,53,3347,1452,801,445,121,1524,1588,2173,195,1453,1653,189,235,691,2367,179,107,891,247,302,333,2105,2180,481,692,217,2314,2,497,165,3039,2319,498,1949,2435,572,437,264,273,1020,2437,2723,1670,1544,2845,1606,2324,933,2259,1737,2725,2560,517,2941,287,664,208,1743,398,1131,355,615,5,782,988,3277,76,1556,294,1313,258,152,2344,317,828,2407,136,100,2057,2516,1367,44,1696,1257,137,3337,378,2216,2459,367,541,3228,1837,1000,133,917,1214,67,1216,1709,2639,509,796,1155,54,2468,2162,2748,3229,632,109,3144,1849,3063,3251,3299,75,299,391,1934 -0.02198676428679048,3.245078698171657,-1.8215870556151397,-0.05052375805598644,0.30691434248850596,0.7108269558541094,2.214438638015626,-0.07924492702588042,-0.10815269963874782,-0.34644068419145774,1.605007630123358,-0.05052375805598644,-0.1372495529245524,1.6247393272059847,1.3820450016487578,0.41136873678446767,-0.43919996831517205,1.7028121530513547,2.333769977004763,0.2537554699892711,1.2981442560194676,1.081263578277897,0.9687588066338071,-0.31594654169938047,-0.34644068419145774,0.6622900003005412,0.41136873678446767,1.5050295510613063,-0.40806438662984673,5.106453588871854,0.6378225083090472,1.7985369233817154,-0.8997389788237078,-0.40806438662984673,0.6378225083090472,-0.25557908848123395,-0.4705554931571856,0.5385907773537494,0.7348993205919421,1.2126457954814382,1.1692778855749448,0.17280963840827135,-0.4705554931571856,-0.6307459142786708,-0.1372495529245524,-0.07924492702588042,-0.7297139540963061,-0.10815269963874782,-0.40806438662984673,0.22693649856222178,-0.37714563952921315,-0.16653801380920247,-0.6307459142786708,-0.5339391468977894,0.6132203653820887,-0.7969425638483784,1.1254866370979533,0.4371047742428398,1.5652826911718993,-0.16653801380920247,0.8299141117114622,0.11801732694304702,0.9229538719151944,0.488136037900703,4.744465578955981,0.3332580754721944,0.1999552233330087,-1.3366301135330916,2.8873405559171093,-0.07924492702588042,1.1034296234289172,0.034544176031171075,1.2555985905367433,1.9840930614703445,-0.40806438662984673,1.0365999791862452,0.30691434248850596,-0.43919996831517205,2.0918689378538042,2.4171181472402936,-0.28566029525923553,-0.5021341373910327,0.0063684354015670136,3.34039786005235,-0.1372495529245524,0.06254274771127205,2.0918689378538042,-1.6539313317624937,0.8766756507402944,-0.34644068419145774,-0.4705554931571856,0.8998745416649946,0.588482059091134,-1.1493154316371736,-0.19602066046695343,0.1999552233330087,2.12722970929693,0.2537554699892711,0.09036639678564706,3.062574077848557,0.09036639678564706,-0.1372495529245524,-0.5659738392609449,0.6378225083090472,0.3332580754721944,0.11801732694304702,3.245078698171657,-0.4705554931571856,-0.31594654169938047,-0.6307459142786708,-1.1493154316371736,0.488136037900703,2.333769977004763,-1.004980242603473,-0.19602066046695343,-0.8997389788237078,-1.2232904675772427,-1.45295805178107,2.9317872528718985,1.1034296234289172,0.8533559354124849,-0.22570012371921228 3367 Sterol metabolic process 17 40 3.225428211954693 0.0012578437675523 Q9UBM7,P48449,Q15800,Q15125,Q14849,Q9BQE5,P61916,Q14739,Q15392,P34913,O15118,P04062,P35610,P05067,Q8WTV0,Q16850,P16435 Processes and pathways GO Biological process msigdb_gobp 325,98,69,166,6,8,197,266,76,207,85,118,308,90,60,94,222 85,2023,2808,118,90,1534,1284,222,3089,207,308,483,3354,2932,98,1466,1886,2892,1545,197,1472,3358,2266,519,3021,339,266,6,3224,166,3225,76,1247,69,94,60,8,325,711,2470 2.7359582136753127,-0.28566029525923553,-0.6964784202356398,2.248856101291637,2.595251590463738,-0.07924492702588042,0.034544176031171075,1.4644074828289309,-0.969620885690122,1.5652826911718993,1.058987402257529,0.6622900003005412,-1.951622338591048,-0.7969425638483784,2.4171181472402936,-0.05052375805598644,-0.22570012371921228,-0.7632007073119792,-0.07924492702588042,1.605007630123358,-0.05052375805598644,-2.176639462165624,-0.37714563952921315,0.6132203653820887,-0.8652075817496219,0.9687588066338071,1.2126457954814382,4.664482621298005,-1.1493154316371736,1.7985369233817154,-1.1493154316371736,2.8873405559171093,0.06254274771127205,2.9611783576004687,2.482708122078919,3.1896999455248927,4.552178889851971,1.014100175743301,0.41136873678446767,-0.4705554931571856 3367 Tetrapyrrole binding 8 18 3.205110775846544 0.0013501050897861 P09601,P30519,Q9H7Z7,O15173,Q8WUJ1,O00264,O43169,Q16850 Functions GO Molecular function msigdb_gomf 0,1,67,74,42,106,79,94 106,3003,74,79,970,0,1458,1,1072,94,226,42,2455,2145,758,67,3140,2967 2.333769977004763,-0.8652075817496219,2.9317872528718985,2.827392685729585,0.1999552233330087,5.77073025593568,-0.05052375805598644,5.215090048676801,0.14549770029311399,2.482708122078919,1.443957948969997,3.3538532991819987,-0.4705554931571856,-0.31594654169938047,0.3594471701790773,3.062574077848557,-1.004980242603473,-0.7969425638483784 3367 Endoplasmic reticulum golgi intermediate compartment membrane 12 22 3.202487579103305 0.0013624617561351 P24390,Q13190,Q9Y3B3,Q9Y282,Q15904,Q10472,Q8N511,P51572,Q96GC9,O95070,O15260,Q08379 Localization GO Cellular component msigdb_gocc 2,355,75,109,173,208,48,273,310,179,121,287 121,1524,1588,2367,179,2,2764,572,437,273,1125,287,208,1131,355,173,48,310,541,1839,109,75 2.214438638015626,-0.07924492702588042,-0.10815269963874782,-0.43919996831517205,1.7028121530513547,5.106453588871854,-0.6634903102109926,0.5385907773537494,0.7348993205919421,1.1692778855749448,0.11801732694304702,1.1254866370979533,1.5652826911718993,0.11801732694304702,0.9229538719151944,1.722120594018782,3.286174597616811,1.058987402257529,0.588482059091134,-0.19602066046695343,2.333769977004763,2.9317872528718985 3367 Carboxylic acid transport 11 29 3.2016120778013333 0.0013666090001871 P07602,P53985,P28288,Q9UBX3,Q9NZJ7,P80404,P30825,P41440,Q15041,Q9H2D1,O60831 Processes and pathways GO Biological process msigdb_gobp 65,103,372,18,276,211,89,186,223,61,158 2363,158,381,1168,1456,2484,1531,65,807,893,372,89,186,1071,103,2322,211,980,519,223,1817,906,1822,61,2636,1002,276,18,546 -0.43919996831517205,1.9292237974120185,0.8533559354124849,0.09036639678564706,-0.05052375805598644,-0.5021341373910327,-0.07924492702588042,3.0911332595741183,0.30691434248850596,0.2537554699892711,0.8766756507402944,2.6583280208911844,1.6639450277501382,0.14549770029311399,2.40057096317167,-0.40806438662984673,1.525203768425511,0.1999552233330087,0.6132203653820887,1.4644074828289309,-0.19602066046695343,0.2537554699892711,-0.19602066046695343,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.1692778855749448,4.015494309311654,0.588482059091134 3367 Abnormal circulating lipid concentration 35 79 3.192511293021213 0.0014104142946267 P31751,O43933,O43772,Q14739,P06280,Q9NZJ7,Q9UJS0,P28070,O43707,Q15125,Q15904,Q9NZC9,Q8N511,Q9BTV4,P50402,Q9UBM7,P07602,Q15800,P61916,P49257,O75381,Q03252,Q8WXH0,Q15392,Q9Y4P3,P56589,P34913,Q9NVI7,O75431,P42858,P50416,P37268,O95470,Q15833,O75844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 257,132,134,266,139,276,546,36,410,166,173,444,48,581,193,325,65,69,197,572,319,328,331,76,205,449,207,475,97,344,485,483,250,501,127 1276,410,2540,134,132,319,97,1395,127,568,250,805,139,1117,65,2179,3362,1347,36,2317,257,207,1661,1662,3176,483,3354,2116,344,2659,572,1466,193,485,2661,1292,2193,2895,449,614,197,1412,1677,328,664,820,3043,1554,266,1426,166,76,1247,69,501,173,2204,2276,1902,2514,48,1089,331,3363,1092,2413,581,763,475,444,276,325,958,546,1108,1163,205,2967,2474 0.034544176031171075,0.7826588994764823,-0.5339391468977894,2.1095839500852342,2.12722970929693,1.014100175743301,2.4171181472402936,-0.02198676428679048,2.16231565108635,0.5385907773537494,1.276921824455599,0.30691434248850596,2.074084118777206,0.11801732694304702,3.0911332595741183,-0.34644068419145774,-3.2895262347862597,0.0063684354015670136,3.473195069920084,-0.40806438662984673,1.2555985905367433,1.5652826911718993,-0.1372495529245524,-0.1372495529245524,-1.0765587039609845,0.6622900003005412,-1.951622338591048,-0.31594654169938047,0.9459148854023514,-0.5982416058990344,0.5385907773537494,-0.05052375805598644,1.6247393272059847,0.6622900003005412,-0.5982416058990344,0.034544176031171075,-0.34644068419145774,-0.7632007073119792,0.7108269558541094,0.488136037900703,1.605007630123358,-0.02198676428679048,-0.1372495529245524,0.9914868411153721,0.4371047742428398,0.30691434248850596,-0.8997389788237078,-0.07924492702588042,1.2126457954814382,-0.02198676428679048,1.7985369233817154,2.8873405559171093,0.06254274771127205,2.9611783576004687,0.6378225083090472,1.722120594018782,-0.34644068419145774,-0.37714563952921315,-0.22570012371921228,-0.5021341373910327,3.286174597616811,0.14549770029311399,0.9914868411153721,-3.344856550142035,0.14549770029311399,-0.43919996831517205,0.5385907773537494,0.3594471701790773,0.6866243286062695,0.7348993205919421,1.1692778855749448,1.014100175743301,0.22693649856222178,0.588482059091134,0.14549770029311399,0.11801732694304702,1.5851890116525102,-0.7969425638483784,-0.4705554931571856 3367 Circulatory system process 20 70 3.1851081652437867 0.0014469991256866 P09601,Q99808,Q96PU5,P42785,Q99996,Q9HB40,P10253,Q9NZ08,P16615,O00429,P42892,P41440,P02786,P80404,P30825,P53985,Q9UIQ6,P08183,Q16625,O75844 Processes and pathways GO Biological process msigdb_gobp 0,259,268,21,160,34,163,168,290,300,43,186,200,211,89,103,105,110,242,127 300,735,2363,1526,1226,1721,127,3253,3330,594,2808,200,3255,1870,610,110,0,163,692,2599,3117,3147,3355,290,436,3012,612,2491,89,186,2032,498,21,43,2254,1666,1465,320,2037,103,2322,1606,1808,934,211,818,819,1476,2847,1963,615,1891,1478,1359,2049,906,242,1822,602,1692,2142,268,259,160,2741,34,877,168,105,567 1.081263578277897,0.3594471701790773,-0.43919996831517205,-0.07924492702588042,0.06254274771127205,-0.16653801380920247,2.16231565108635,-1.2607479309781038,-1.6129965081754174,0.5134346459158582,-0.6964784202356398,1.5851890116525102,-1.2607479309781038,-0.22570012371921228,0.488136037900703,2.2999956417932186,5.77073025593568,1.8362643641609107,0.41136873678446767,-0.5659738392609449,-1.004980242603473,-1.0406246148817728,-1.9957969029261853,1.1034296234289172,0.7348993205919421,-0.8652075817496219,0.488136037900703,-0.5021341373910327,2.6583280208911844,1.6639450277501382,-0.28566029525923553,0.6378225083090472,3.8498324746709085,3.34039786005235,-0.37714563952921315,-0.1372495529245524,-0.05052375805598644,1.014100175743301,-0.28566029525923553,2.40057096317167,-0.40806438662984673,-0.10815269963874782,-0.19602066046695343,0.22693649856222178,1.525203768425511,0.30691434248850596,0.30691434248850596,-0.05052375805598644,-0.7297139540963061,-0.25557908848123395,0.488136037900703,-0.22570012371921228,-0.05052375805598644,0.0063684354015670136,-0.28566029525923553,0.2537554699892711,1.3402905479186136,-0.19602066046695343,0.5134346459158582,-0.1372495529245524,-0.31594654169938047,1.2126457954814382,1.2555985905367433,1.8736785287250628,-0.6307459142786708,3.525248122809391,0.2804141068248859,1.7795540517583925,2.36729383704207,0.5636060512556167 3367 Lytic vacuole organization 8 25 3.1819327346529445 0.0014629579157554 Q14108,O14773,O75503,P11117,Q8N511,P54802,P04062,P50897 Processes and pathways GO Biological process msigdb_gobp 5,70,102,108,48,83,118,26 2171,70,102,891,118,1064,163,108,498,26,1019,83,2259,321,5,598,364,48,1318,1209,2528,2796,2963,2293,1335 -0.34644068419145774,2.9465065973455364,2.40057096317167,0.2537554699892711,2.248856101291637,0.14549770029311399,1.8362643641609107,2.333769977004763,0.6378225083090472,3.6904275097045454,0.17280963840827135,2.7513259355917703,-0.37714563952921315,1.014100175743301,4.744465578955981,0.5134346459158582,0.8998745416649946,3.286174597616811,0.034544176031171075,0.09036639678564706,-0.5021341373910327,-0.6634903102109926,-0.7969425638483784,-0.37714563952921315,0.034544176031171075 3367 Ion transport 68 180 3.180706618856896 0.0014691633061831 Q658P3,Q99808,Q9H0U3,Q9BVC6,O43772,P46934,P50570,O75746,Q6P4Q7,P51798,P21796,Q96PU5,Q13131,O76024,Q9UBX3,P45880,Q9Y277,P00403,Q70HW3,Q9UJS0,Q9NZJ7,O14936,Q8IYU8,O60831,Q99996,P24539,P46939,O43707,Q9UHG3,P13073,Q9UDW1,Q15043,P16615,Q8TB61,O75964,O43808,O00429,P05141,Q96GC9,P20020,P06576,P12236,P41440,Q9H2D1,P30536,P07602,Q9HC21,Q13423,Q9C0H2,P02786,O15173,P12235,P80404,P30825,P05067,Q8NE01,Q15041,O96008,P42858,P53985,P47985,P08183,Q9HD20,P25705,P28288,O95202,P27105,O75844 Processes and pathways GO Biological process msigdb_gobp 129,259,387,385,134,262,264,381,400,516,13,268,519,393,18,19,548,145,22,546,276,277,534,158,160,411,413,410,37,167,40,293,290,44,45,549,300,553,310,436,435,307,186,61,191,65,324,71,72,200,74,447,211,89,90,351,223,466,344,103,484,110,115,244,372,123,124,127 2645,300,1389,2363,277,74,738,410,134,549,2303,158,1015,3008,2096,2807,1862,2595,381,127,1168,1938,45,393,123,1456,2426,466,145,200,2484,1870,610,90,553,1531,435,2370,2549,65,1655,110,807,970,2180,1872,692,1658,1534,447,307,167,1942,893,290,772,1181,436,1797,1537,2377,3012,13,411,1183,244,124,3070,612,372,3091,191,2491,89,3038,613,742,3195,2318,1539,2976,186,344,19,2552,262,413,484,3321,264,516,1071,103,1887,2608,1126,2322,1073,1127,850,746,852,1808,3158,934,211,1548,817,1355,980,1076,1889,2444,2499,1890,1815,519,71,1304,821,1891,1554,2505,223,1817,293,3277,906,2336,129,2340,599,1822,400,1029,22,1758,534,1692,351,1493,44,1090,1038,310,2739,268,3280,1507,259,160,1376,385,72,1213,387,61,2741,2636,1002,324,115,1709,276,18,40,2162,37,2470,585,546,1579,1847,2641,960,548,1521,2088,734,2536 -0.5982416058990344,1.081263578277897,-0.02198676428679048,-0.43919996831517205,1.1474357022138544,2.9317872528718985,0.3594471701790773,0.7826588994764823,2.1095839500852342,0.5636060512556167,-0.40806438662984673,1.9292237974120185,0.17280963840827135,-0.8652075817496219,-0.31594654169938047,-0.6964784202356398,-0.22570012371921228,-0.5659738392609449,0.8533559354124849,2.16231565108635,0.09036639678564706,-0.25557908848123395,3.286174597616811,0.8299141117114622,2.19713106377011,-0.05052375805598644,-0.4705554931571856,0.6866243286062695,2.002235460610414,1.5851890116525102,-0.5021341373910327,-0.22570012371921228,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,0.7348993205919421,-0.43919996831517205,-0.5339391468977894,3.0911332595741183,-0.1372495529245524,2.2999956417932186,0.30691434248850596,0.1999552233330087,-0.34644068419145774,-0.22570012371921228,0.41136873678446767,-0.1372495529245524,-0.07924492702588042,0.7108269558541094,1.058987402257529,1.7795540517583925,-0.25557908848123395,0.2537554699892711,1.1034296234289172,0.3332580754721944,0.09036639678564706,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8652075817496219,4.220028343416946,0.7826588994764823,0.09036639678564706,1.3192668476331657,2.19713106377011,-0.9345419567612725,0.488136037900703,0.8766756507402944,-0.969620885690122,1.6247393272059847,-0.5021341373910327,2.6583280208911844,-0.8997389788237078,0.488136037900703,0.3594471701790773,-1.112787329154505,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,1.6639450277501382,0.9459148854023514,3.9215673900004977,-0.5339391468977894,1.2341735778065615,0.7826588994764823,0.6622900003005412,-1.5724386516725661,1.2126457954814382,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.22570012371921228,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.2804141068248859,0.3594471701790773,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,1.525203768425511,-0.07924492702588042,0.30691434248850596,0.0063684354015670136,0.1999552233330087,0.14549770029311399,-0.22570012371921228,-0.4705554931571856,-0.5021341373910327,-0.22570012371921228,-0.19602066046695343,0.6132203653820887,2.9465065973455364,0.034544176031171075,0.30691434248850596,-0.22570012371921228,-0.07924492702588042,-0.5021341373910327,1.4644074828289309,-0.19602066046695343,1.1034296234289172,-1.3366301135330916,0.2537554699892711,-0.40806438662984673,2.16231565108635,-0.40806438662984673,0.5134346459158582,-0.19602066046695343,0.8299141117114622,0.17280963840827135,3.8256681593087887,-0.16653801380920247,0.588482059091134,-0.1372495529245524,0.9459148854023514,-0.05052375805598644,3.34039786005235,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,-1.3366301135330916,-0.05052375805598644,1.2555985905367433,1.8736785287250628,0.0063684354015670136,0.8533559354124849,2.9465065973455364,0.09036639678564706,0.8533559354124849,3.161755509768943,-0.6307459142786708,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,-0.1372495529245524,1.1692778855749448,4.015494309311654,3.380645404831543,-0.31594654169938047,3.473195069920084,-0.4705554931571856,0.5385907773537494,0.588482059091134,-0.07924492702588042,-0.19602066046695343,-0.5659738392609449,0.22693649856222178,0.588482059091134,-0.05052375805598644,-0.28566029525923553,0.3854834577363446,-0.5021341373910327 3367 Secondary alcohol metabolic process 17 43 3.1738686315934976 0.0015042175521977 Q9UBM7,P48449,Q15800,Q15125,Q14849,Q9BQE5,P61916,Q14739,Q15392,P34913,O15118,P04062,P35610,P05067,Q8WTV0,Q16850,P16435 Processes and pathways GO Biological process msigdb_gobp 325,98,69,166,6,8,197,266,76,207,85,118,308,90,60,94,222 85,2541,3145,2023,2808,118,90,1534,1284,222,3089,207,308,483,2932,98,3196,1466,3247,1886,2892,1545,197,1472,3358,2266,519,3021,339,266,6,3224,166,3225,76,1247,69,94,60,2862,8,325,711 2.7359582136753127,-0.5339391468977894,-1.0406246148817728,-0.28566029525923553,-0.6964784202356398,2.248856101291637,2.595251590463738,-0.07924492702588042,0.034544176031171075,1.4644074828289309,-0.969620885690122,1.5652826911718993,1.058987402257529,0.6622900003005412,-0.7969425638483784,2.4171181472402936,-1.112787329154505,-0.05052375805598644,-1.2232904675772427,-0.22570012371921228,-0.7632007073119792,-0.07924492702588042,1.605007630123358,-0.05052375805598644,-2.176639462165624,-0.37714563952921315,0.6132203653820887,-0.8652075817496219,0.9687588066338071,1.2126457954814382,4.664482621298005,-1.1493154316371736,1.7985369233817154,-1.1493154316371736,2.8873405559171093,0.06254274771127205,2.9611783576004687,2.482708122078919,3.1896999455248927,-0.7297139540963061,4.552178889851971,1.014100175743301,0.41136873678446767 3367 Abnormality of corneal stroma 7 17 3.171812381559109 0.0015149084321366 P10619,O43505,O43933,P16278,Q13510,P34913,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 190,195,132,41,78,207,118 195,132,118,190,41,1286,975,207,2115,1470,1963,78,242,990,1501,444,2296 1.605007630123358,2.12722970929693,2.248856101291637,1.6247393272059847,3.367269068562799,0.034544176031171075,0.1999552233330087,1.5652826911718993,-0.31594654169938047,-0.05052375805598644,-0.25557908848123395,2.8724277004854066,1.3402905479186136,0.1999552233330087,-0.05052375805598644,0.7348993205919421,-0.37714563952921315 3367 Dementia 21 61 3.162261527679354 0.0015654889901517 Q14108,O76024,P00403,Q9NZJ7,O60313,Q96RL7,O00429,P17900,P35637,P07602,P61916,Q13510,P06865,O15118,Q9Y487,Q14203,P05067,P27544,P42858,P20700,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 5,393,145,276,279,297,300,169,192,65,197,78,81,85,215,468,90,467,344,359,118 300,85,738,279,1527,393,466,145,118,3283,1283,90,81,65,1657,2810,555,169,359,2430,1017,2027,467,2604,2930,192,1539,2976,344,1186,2037,1470,2818,197,1416,1191,1889,2501,1553,78,5,468,1894,1753,1976,830,1433,539,1501,2411,1209,297,1094,3280,650,276,686,1386,2966,215,2967 1.081263578277897,2.7359582136753127,0.3594471701790773,1.1474357022138544,-0.07924492702588042,0.8299141117114622,0.6866243286062695,2.002235460610414,2.248856101291637,-1.37506621536203,0.034544176031171075,2.595251590463738,2.781905953857426,3.0911332595741183,-0.1372495529245524,-0.6964784202356398,0.5636060512556167,1.7413465847323417,0.8998745416649946,-0.4705554931571856,0.17280963840827135,-0.28566029525923553,0.6866243286062695,-0.5659738392609449,-0.7969425638483784,1.6247393272059847,-0.07924492702588042,-0.8309434988946349,0.9459148854023514,0.09036639678564706,-0.28566029525923553,-0.05052375805598644,-0.6964784202356398,1.605007630123358,-0.02198676428679048,0.09036639678564706,-0.22570012371921228,-0.5021341373910327,-0.07924492702588042,2.8724277004854066,4.744465578955981,0.6866243286062695,-0.22570012371921228,-0.16653801380920247,-0.25557908848123395,0.30691434248850596,-0.02198676428679048,0.588482059091134,-0.05052375805598644,-0.43919996831517205,0.09036639678564706,1.1034296234289172,0.14549770029311399,-1.3366301135330916,0.46269330605308917,1.1692778855749448,0.4371047742428398,0.0063684354015670136,-0.7969425638483784,1.525203768425511,-0.7969425638483784 3367 Endocytic vesicle membrane 13 40 3.136699699322335 0.0017086103336381 P11717,Q14108,P11279,P50570,Q5KU26,P02786,P01889,Q93050,P13473,Q9Y487,P04439,P20645,Q8WTV0 Localization GO Cellular component msigdb_gocc 217,5,261,264,171,200,302,92,210,215,333,185,60 2538,1588,2367,1281,1062,302,200,333,481,261,217,210,773,185,2764,264,1019,813,2324,933,746,1956,817,1677,1476,345,821,1891,5,1360,3277,171,2621,60,92,835,1210,2528,2296,215 -0.5339391468977894,-0.10815269963874782,-0.43919996831517205,0.034544176031171075,0.14549770029311399,1.081263578277897,1.5851890116525102,0.9687588066338071,0.6622900003005412,1.2341735778065615,1.5050295510613063,1.5452878774447738,0.3332580754721944,1.6639450277501382,-0.6634903102109926,1.2126457954814382,0.17280963840827135,0.30691434248850596,-0.40806438662984673,0.22693649856222178,0.3594471701790773,-0.25557908848123395,0.30691434248850596,-0.1372495529245524,-0.05052375805598644,0.9459148854023514,0.30691434248850596,-0.22570012371921228,4.744465578955981,0.0063684354015670136,-1.3366301135330916,1.7413465847323417,-0.5659738392609449,3.1896999455248927,2.5793442451134623,0.30691434248850596,0.09036639678564706,-0.5021341373910327,-0.37714563952921315,1.525203768425511 3367 Organophosphate ester transport 16 25 3.117626356561407 0.0018231377669215 Q99808,Q9HC21,Q9BZF1,Q14108,P61916,P12235,Q8TB61,O43808,Q9BSK2,P08183,P05141,Q96GC9,P12236,P41440,Q8WTV0,Q9H2D1 Processes and pathways GO Biological process msigdb_gobp 259,324,491,5,197,447,44,549,209,110,553,310,307,186,60,61 549,553,110,447,307,2314,2929,186,2435,197,1547,2396,5,599,44,60,310,259,209,491,761,61,324,1155,1009 0.5636060512556167,0.5636060512556167,2.2999956417932186,0.7108269558541094,1.058987402257529,-0.40806438662984673,-0.7969425638483784,1.6639450277501382,-0.4705554931571856,1.605007630123358,-0.07924492702588042,-0.43919996831517205,4.744465578955981,0.5134346459158582,3.34039786005235,3.1896999455248927,1.058987402257529,1.2555985905367433,1.5652826911718993,0.6622900003005412,0.3594471701790773,3.161755509768943,1.014100175743301,0.11801732694304702,0.1999552233330087 3367 Mitochondrial substrate/solute carrier [IPR018108] 14 19 3.1171707205582275 0.00182595799046 Q9HC21,O43772,O75746,P12235,O43808,Q9BSK2,Q9UBX3,Q9Y6C9,Q9NZJ7,P05141,Q9UJS0,Q70HW3,P12236,Q9H2D1 Sequence InterPro Repeat interpro_repeat 324,134,381,447,549,209,18,306,276,553,546,22,307,61 134,549,381,553,447,307,1071,1548,980,599,22,209,61,2636,324,276,18,546,306 2.1095839500852342,0.5636060512556167,0.8533559354124849,0.5636060512556167,0.7108269558541094,1.058987402257529,0.14549770029311399,-0.07924492702588042,0.1999552233330087,0.5134346459158582,3.8256681593087887,1.5652826911718993,3.161755509768943,-0.5659738392609449,1.014100175743301,1.1692778855749448,4.015494309311654,0.588482059091134,1.081263578277897 3367 SLC25 family of mitochondrial transporters 14 19 3.1171707205582275 0.00182595799046 Q9HC21,O43772,O75746,P12235,O43808,Q9BSK2,Q9UBX3,Q9Y6C9,Q9NZJ7,P05141,Q9UJS0,Q70HW3,P12236,Q9H2D1 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 324,134,381,447,549,209,18,306,276,553,546,22,307,61 134,549,381,553,447,307,1071,1548,980,599,22,209,61,2636,324,276,18,546,306 2.1095839500852342,0.5636060512556167,0.8533559354124849,0.5636060512556167,0.7108269558541094,1.058987402257529,0.14549770029311399,-0.07924492702588042,0.1999552233330087,0.5134346459158582,3.8256681593087887,1.5652826911718993,3.161755509768943,-0.5659738392609449,1.014100175743301,1.1692778855749448,4.015494309311654,0.588482059091134,1.081263578277897 3367 Mitochondrial carrier domain superfamily [IPR023395] 14 19 3.1171707205582275 0.00182595799046 Q9HC21,O43772,O75746,P12235,O43808,Q9BSK2,Q9UBX3,Q9Y6C9,Q9NZJ7,P05141,Q9UJS0,Q70HW3,P12236,Q9H2D1 Sequence InterPro Superfamily interpro_homologous_superfamily 324,134,381,447,549,209,18,306,276,553,546,22,307,61 134,549,381,553,447,307,1071,1548,980,599,22,209,61,2636,324,276,18,546,306 2.1095839500852342,0.5636060512556167,0.8533559354124849,0.5636060512556167,0.7108269558541094,1.058987402257529,0.14549770029311399,-0.07924492702588042,0.1999552233330087,0.5134346459158582,3.8256681593087887,1.5652826911718993,3.161755509768943,-0.5659738392609449,1.014100175743301,1.1692778855749448,4.015494309311654,0.588482059091134,1.081263578277897 3367 Ion homeostasis 34 97 3.1016738065196474 0.0019242987089234 P09601,P30519,Q658P3,Q6P4Q7,Q96PU5,O76024,P51572,Q96A33,P50897,Q8IYU8,Q15043,P16615,Q9Y5X3,Q15904,Q8N511,P20020,P06576,Q9UI12,P30536,O75880,P02786,Q96TC7,Q9Y487,P05067,O60826,Q93050,Q8NE01,P42858,O75503,Q92544,P28161,Q16891,Q9HD20,O95202 Processes and pathways GO Biological process msigdb_gobp 0,1,129,400,268,393,273,274,26,534,293,290,567,173,48,436,435,585,191,568,200,343,215,90,593,92,351,344,102,489,612,363,115,123 2171,1452,2363,654,2303,593,1015,102,568,3253,393,2548,123,926,891,200,3255,1870,610,90,435,1064,1655,1656,0,2374,2180,2881,1942,1118,290,1181,436,774,2763,3070,2764,612,2431,1,191,2491,2976,344,1666,1465,26,1019,273,1126,2322,746,1808,3158,2938,934,1417,1815,3290,2042,1891,1554,1359,293,3277,173,363,129,400,1029,1758,534,1692,48,351,1493,868,1090,489,92,274,1318,2739,268,343,1376,1512,2741,115,2162,585,1579,1581,215,734,567,2536 -0.34644068419145774,-0.05052375805598644,-0.43919996831517205,0.4371047742428398,-0.40806438662984673,0.5134346459158582,0.17280963840827135,2.40057096317167,0.5385907773537494,-1.2607479309781038,0.8299141117114622,-0.5339391468977894,2.19713106377011,0.22693649856222178,0.2537554699892711,1.5851890116525102,-1.2607479309781038,-0.22570012371921228,0.488136037900703,2.595251590463738,0.7348993205919421,0.14549770029311399,-0.1372495529245524,-0.1372495529245524,5.77073025593568,-0.43919996831517205,-0.34644068419145774,-0.7632007073119792,-0.25557908848123395,0.11801732694304702,1.1034296234289172,0.09036639678564706,0.7348993205919421,0.3332580754721944,-0.6634903102109926,-0.9345419567612725,-0.6634903102109926,0.488136037900703,-0.4705554931571856,5.215090048676801,1.6247393272059847,-0.5021341373910327,-0.8309434988946349,0.9459148854023514,-0.1372495529245524,-0.05052375805598644,3.6904275097045454,0.17280963840827135,1.1692778855749448,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.19602066046695343,-1.0406246148817728,-0.7969425638483784,0.22693649856222178,-0.02198676428679048,-0.19602066046695343,-1.4138401674883982,-0.28566029525923553,-0.22570012371921228,-0.07924492702588042,0.0063684354015670136,1.1034296234289172,-1.3366301135330916,1.722120594018782,0.8998745416649946,2.16231565108635,0.8299141117114622,0.17280963840827135,-0.16653801380920247,0.588482059091134,-0.1372495529245524,3.286174597616811,0.9459148854023514,-0.05052375805598644,0.2804141068248859,0.14549770029311399,0.6622900003005412,2.5793442451134623,1.1692778855749448,0.034544176031171075,-0.6307459142786708,1.2126457954814382,0.9687588066338071,0.0063684354015670136,-0.05052375805598644,-0.6307459142786708,2.283013353361886,-0.31594654169938047,0.5385907773537494,-0.07924492702588042,-0.07924492702588042,1.525203768425511,0.3854834577363446,0.5636060512556167,-0.5021341373910327 3367 Clathrin coated vesicle 9 45 3.097826676525377 0.0019494540657607 O43752,P11717,Q14108,P50570,P02786,P42892,Q5VW38,P20645,Q9Y5X1 Localization GO Cellular component msigdb_gocc 189,217,5,264,200,43,16,185,30 2171,1225,735,1653,189,3282,1281,1062,200,554,1594,1940,217,773,185,43,437,264,3152,273,813,2324,2259,1956,817,1677,1078,2042,5,2202,1360,16,1318,835,541,1837,1921,1572,1709,2001,2293,2748,2294,1520,30 -0.34644068419145774,0.06254274771127205,0.3594471701790773,-0.1372495529245524,1.6247393272059847,-1.37506621536203,0.034544176031171075,0.14549770029311399,1.5851890116525102,0.5636060512556167,-0.10815269963874782,-0.25557908848123395,1.5050295510613063,0.3332580754721944,1.6639450277501382,3.34039786005235,0.7348993205919421,1.2126457954814382,-1.0406246148817728,1.1692778855749448,0.30691434248850596,-0.40806438662984673,-0.37714563952921315,-0.25557908848123395,0.30691434248850596,-0.1372495529245524,0.14549770029311399,-0.28566029525923553,4.744465578955981,-0.34644068419145774,0.0063684354015670136,4.130251742479455,0.034544176031171075,0.30691434248850596,0.588482059091134,-0.19602066046695343,-0.22570012371921228,-0.07924492702588042,-0.1372495529245524,-0.25557908848123395,-0.37714563952921315,-0.6307459142786708,-0.37714563952921315,-0.05052375805598644,3.614933961940769 3367 Carbohydrate derivative transport 12 14 3.0961232766182003 0.0019606882822125 Q99808,P07602,Q9HC21,P61916,P12235,Q8TB61,O43808,P05141,Q9NZJ7,P12236,P41440,Q8WTV0 Processes and pathways GO Biological process msigdb_gobp 259,65,324,197,447,44,549,553,276,307,186,60 1388,549,553,65,447,307,186,197,599,44,60,259,324,276 -0.02198676428679048,0.5636060512556167,0.5636060512556167,3.0911332595741183,0.7108269558541094,1.058987402257529,1.6639450277501382,1.605007630123358,0.5134346459158582,3.34039786005235,3.1896999455248927,1.2555985905367433,1.014100175743301,1.1692778855749448 3367 Membrane lipid catabolic process 8 12 3.090043698887206 0.0020012704856076 P06280,P17900,Q13510,Q99735,P06865,P04062,P04066,P50897 Processes and pathways GO Biological process msigdb_gobp 139,169,78,147,81,118,184,26 250,118,184,139,81,1064,169,26,2396,78,147,796 1.276921824455599,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,0.14549770029311399,1.7413465847323417,3.6904275097045454,-0.43919996831517205,2.8724277004854066,2.002235460610414,0.3332580754721944 3367 Alcohol binding 7 17 3.0845308202867963 0.0020387348551931 P30536,Q14108,P61916,Q14849,P21796,P45880,O15118 Functions GO Molecular function msigdb_gomf 191,5,197,6,13,19,85 1113,85,1654,2023,1655,13,2929,1184,191,308,19,197,5,6,491,761,582 0.11801732694304702,2.7359582136753127,-0.1372495529245524,-0.28566029525923553,-0.1372495529245524,4.220028343416946,-0.7969425638483784,0.09036639678564706,1.6247393272059847,1.058987402257529,3.9215673900004977,1.605007630123358,4.744465578955981,4.664482621298005,0.6622900003005412,0.3594471701790773,0.5385907773537494 3367 Glycosphingolipid metabolism 8 15 3.081247212996888 0.0020613542565244 P10619,P07602,P16278,P06280,P17900,Q13510,P06865,P04062 Processes and pathways Reactome Pathways msigdb_reactome 190,65,41,139,169,78,81,118 589,738,118,139,81,65,1064,190,555,41,169,78,2693,796,276 0.5134346459158582,0.3594471701790773,2.248856101291637,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,1.6247393272059847,0.5636060512556167,3.367269068562799,1.7413465847323417,2.8724277004854066,-0.5982416058990344,0.3332580754721944,1.1692778855749448 3367 Protein targeting 35 108 3.0629929767851425 0.0021913520282323 O00560,Q9NS69,O43933,Q14108,P46934,O60830,O43615,Q99595,Q15629,Q10713,O14964,P43307,P51572,O60725,P46379,O14737,O95831,Q96RL7,Q99442,P20645,Q9H9H4,P30536,P49840,O75381,P56589,P13473,P55786,Q15041,O96008,O14925,Q9P0J0,Q9Y5M8,Q5JRX3,P27105,P31751 Processes and pathways GO Biological process msigdb_gobp 495,3,132,5,262,9,513,11,10,398,392,17,273,144,29,284,35,297,176,185,460,191,320,319,449,210,84,223,466,464,230,120,375,124,257 1275,1854,2171,495,1452,284,464,392,513,738,1055,132,144,9,319,2595,2547,2649,3254,2305,2369,35,466,969,2177,3034,1940,210,2759,185,1944,124,2884,3070,191,3219,257,1235,2432,2931,17,29,262,572,897,320,1019,273,84,449,3286,3222,899,2194,852,1673,1808,3018,2394,2846,398,1815,1078,519,5,1025,223,10,3045,749,826,698,375,2512,1976,719,909,2053,2344,2737,943,1627,297,2690,176,1506,1210,11,3056,1327,460,2797,3,1926,230,2746,766,1106,2162,2747,3165,844,3299,1386,2088,565,1853,120 0.034544176031171075,-0.22570012371921228,-0.34644068419145774,0.6378225083090472,-0.05052375805598644,1.1254866370979533,0.6866243286062695,0.8299141117114622,0.6132203653820887,0.3594471701790773,0.14549770029311399,2.12722970929693,2.002235460610414,4.521067264147013,1.014100175743301,-0.5659738392609449,-0.5339391468977894,-0.5982416058990344,-1.2607479309781038,-0.40806438662984673,-0.43919996831517205,3.512290521765781,0.6866243286062695,0.1999552233330087,-0.34644068419145774,-0.8997389788237078,-0.25557908848123395,1.5452878774447738,-0.6634903102109926,1.6639450277501382,-0.25557908848123395,2.19713106377011,-0.7632007073119792,-0.9345419567612725,1.6247393272059847,-1.1493154316371736,1.2555985905367433,0.06254274771127205,-0.4705554931571856,-0.7969425638483784,4.027100565880452,3.614933961940769,1.2341735778065615,0.5385907773537494,0.2537554699892711,1.014100175743301,0.17280963840827135,1.1692778855749448,2.7513259355917703,0.7108269558541094,-1.37506621536203,-1.1493154316371736,0.2537554699892711,-0.34644068419145774,0.2804141068248859,-0.1372495529245524,-0.19602066046695343,-0.8652075817496219,-0.43919996831517205,-0.7297139540963061,0.8299141117114622,-0.19602066046695343,0.14549770029311399,0.6132203653820887,4.744465578955981,0.17280963840827135,1.4644074828289309,4.2752571823438945,-0.8997389788237078,0.3594471701790773,0.30691434248850596,0.41136873678446767,0.8766756507402944,-0.5021341373910327,-0.25557908848123395,0.3854834577363446,0.2537554699892711,-0.28566029525923553,-0.40806438662984673,-0.6307459142786708,0.22693649856222178,-0.10815269963874782,1.1034296234289172,-0.5982416058990344,1.722120594018782,-0.05052375805598644,0.09036639678564706,4.253245556056843,-0.8997389788237078,0.034544176031171075,0.7108269558541094,-0.6634903102109926,4.832811783410612,-0.22570012371921228,1.4234149403548129,-0.6307459142786708,0.3594471701790773,0.14549770029311399,-0.31594654169938047,-0.6307459142786708,-1.0406246148817728,0.30691434248850596,-1.45295805178107,0.0063684354015670136,-0.28566029525923553,0.5636060512556167,-0.19602066046695343,2.2316801472635333 3367 Ceramide metabolic process 11 18 3.057545012474381 0.0022315812294197 O15269,Q96G23,P06280,P17900,Q13510,P06865,Q99805,P04062,O95470,P27544,Q8NCC3 Processes and pathways GO Biological process msigdb_gobp 220,66,139,169,78,81,379,118,250,467,63 220,965,250,118,139,81,1064,169,467,1405,2396,519,78,698,63,66,379,796 1.4644074828289309,0.1999552233330087,1.276921824455599,2.248856101291637,2.074084118777206,2.781905953857426,0.14549770029311399,1.7413465847323417,0.6866243286062695,-0.02198676428679048,-0.43919996831517205,0.6132203653820887,2.8724277004854066,0.41136873678446767,3.1336381893089387,3.0911332595741183,0.8766756507402944,0.3332580754721944 3367 Endoplasmic reticulum organization 16 38 3.0534703763363327 0.0022621105486837 Q9NQC3,Q12981,P49257,Q00765,Q15629,O00429,O95197,Q96A33,Q15041,Q9P2W9,A0MZ66,Q8NHH9,P57088,P46379,A0FGR8,Q8NFQ8 Processes and pathways GO Biological process msigdb_gobp 96,499,572,574,10,300,107,274,223,54,332,538,316,29,589,377 589,332,300,1935,801,738,1055,1230,107,926,29,572,316,933,852,574,1131,499,1425,223,1817,10,1135,1428,646,719,912,377,538,274,2693,955,3080,1218,96,796,1155,54 0.5134346459158582,0.9687588066338071,1.081263578277897,-0.25557908848123395,0.30691434248850596,0.3594471701790773,0.14549770029311399,0.06254274771127205,2.333769977004763,0.22693649856222178,3.614933961940769,0.5385907773537494,1.0365999791862452,0.22693649856222178,0.2804141068248859,0.5385907773537494,0.11801732694304702,0.6378225083090472,-0.02198676428679048,1.4644074828289309,-0.19602066046695343,4.2752571823438945,0.11801732694304702,-0.02198676428679048,0.46269330605308917,0.3854834577363446,0.2537554699892711,0.8766756507402944,0.588482059091134,1.1692778855749448,-0.5982416058990344,0.22693649856222178,-0.9345419567612725,0.09036639678564706,2.433605013064534,0.3332580754721944,0.11801732694304702,3.245078698171657 3367 Abnormal circulating cholesterol concentration 18 33 3.053324665486723 0.002263209344228 Q9UBM7,O75431,P07602,P42858,Q15800,Q15125,P61916,Q14739,Q8WXH0,Q15392,Q15904,P37268,Q8N511,P34913,Q9NZJ7,Q9NVI7,Q9UJS0,P50402 Drugs and Diseases Human Phenotype Ontology msigdb_hp 325,97,65,344,69,166,197,266,331,76,173,483,48,207,276,475,546,193 97,805,1117,65,207,483,3354,344,2659,193,2661,614,197,1677,664,820,1554,266,166,76,1247,69,173,1902,2514,48,1089,331,581,475,276,325,546 2.4171181472402936,0.30691434248850596,0.11801732694304702,3.0911332595741183,1.5652826911718993,0.6622900003005412,-1.951622338591048,0.9459148854023514,-0.5982416058990344,1.6247393272059847,-0.5982416058990344,0.488136037900703,1.605007630123358,-0.1372495529245524,0.4371047742428398,0.30691434248850596,-0.07924492702588042,1.2126457954814382,1.7985369233817154,2.8873405559171093,0.06254274771127205,2.9611783576004687,1.722120594018782,-0.22570012371921228,-0.5021341373910327,3.286174597616811,0.14549770029311399,0.9914868411153721,0.5385907773537494,0.6866243286062695,1.1692778855749448,1.014100175743301,0.588482059091134 3367 Arthritis 18 45 3.048302273200686 0.0023013830755154 Q8WVQ1,Q9NUQ7,Q96RL7,Q14108,P28070,P21964,Q9NZ08,Q14739,P06280,Q8NBM4,P60891,P01889,Q13510,Q96HY6,P10321,P04062,Q7Z406,O75844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 457,493,297,5,36,396,168,266,139,425,450,302,78,342,481,118,503,127 1854,3065,2924,127,2927,302,805,118,139,1723,481,2486,893,396,2656,36,743,1124,1803,516,1670,2258,932,450,852,1677,2266,2396,78,5,266,2333,503,425,457,1982,2410,342,297,1440,493,168,687,2591,2298 -0.22570012371921228,-0.9345419567612725,-0.7969425638483784,2.16231565108635,-0.7969425638483784,1.081263578277897,0.30691434248850596,2.248856101291637,2.074084118777206,-0.16653801380920247,0.6622900003005412,-0.5021341373910327,0.2537554699892711,0.8299141117114622,-0.5982416058990344,3.473195069920084,0.3594471701790773,0.11801732694304702,-0.19602066046695343,0.6132203653820887,-0.1372495529245524,-0.37714563952921315,0.22693649856222178,0.7108269558541094,0.2804141068248859,-0.1372495529245524,-0.37714563952921315,-0.43919996831517205,2.8724277004854066,4.744465578955981,1.2126457954814382,-0.40806438662984673,0.6378225083090472,0.7588428378146155,0.7108269558541094,-0.25557908848123395,-0.43919996831517205,0.9687588066338071,1.1034296234289172,-0.02198676428679048,0.6622900003005412,1.7795540517583925,0.4371047742428398,-0.5339391468977894,-0.37714563952921315 3367 Steroid metabolic process 24 71 3.044292491918643 0.0023322826464597 P38435,Q14849,Q9BQE5,Q14739,Q53GQ0,Q15125,P35610,Q8WTV0,P30536,Q9UBM7,Q15800,P61916,Q15392,Q13510,P34913,Q14534,O15118,P05067,Q16850,P16435,P48449,P28288,P04062,O95470 Processes and pathways GO Biological process msigdb_gobp 383,6,8,266,295,166,308,60,191,325,69,197,76,78,207,339,85,90,94,222,98,372,118,250 2708,1390,85,2023,250,2808,118,610,90,3033,1534,1284,2928,222,2314,2929,3089,2882,372,191,207,308,483,383,3354,2932,98,1466,2037,1292,1886,2892,1545,197,1472,3358,2266,1076,519,78,3021,339,266,6,3224,166,3225,76,1245,1308,1247,69,94,295,598,403,60,2143,1096,507,3026,8,2794,761,917,582,325,711,1450,2470,3312 -0.6307459142786708,-0.02198676428679048,2.7359582136753127,-0.28566029525923553,1.276921824455599,-0.6964784202356398,2.248856101291637,0.488136037900703,2.595251590463738,-0.8997389788237078,-0.07924492702588042,0.034544176031171075,-0.7969425638483784,1.4644074828289309,-0.40806438662984673,-0.7969425638483784,-0.969620885690122,-0.7632007073119792,0.8766756507402944,1.6247393272059847,1.5652826911718993,1.058987402257529,0.6622900003005412,0.8533559354124849,-1.951622338591048,-0.7969425638483784,2.4171181472402936,-0.05052375805598644,-0.28566029525923553,0.034544176031171075,-0.22570012371921228,-0.7632007073119792,-0.07924492702588042,1.605007630123358,-0.05052375805598644,-2.176639462165624,-0.37714563952921315,0.14549770029311399,0.6132203653820887,2.8724277004854066,-0.8652075817496219,0.9687588066338071,1.2126457954814382,4.664482621298005,-1.1493154316371736,1.7985369233817154,-1.1493154316371736,2.8873405559171093,0.06254274771127205,0.034544176031171075,0.06254274771127205,2.9611783576004687,2.482708122078919,1.1034296234289172,0.5134346459158582,0.8063488749900722,3.1896999455248927,-0.31594654169938047,0.14549770029311399,0.6378225083090472,-0.8652075817496219,4.552178889851971,-0.6634903102109926,0.3594471701790773,0.2537554699892711,0.5385907773537494,1.014100175743301,0.41136873678446767,-0.02198676428679048,-0.4705554931571856,-1.4924261166507573 3367 Organic anion transmembrane transporter activity 14 25 3.041778137160612 0.0023518517182998 Q99808,Q9HC21,O75746,P53985,P12235,Q8TB61,O43808,Q9UBX3,P05141,Q9UJS0,P12236,P30825,P41440,Q9H2D1 Functions GO Molecular function msigdb_gomf 259,324,381,103,447,44,549,18,553,546,307,89,186,61 2363,549,381,1456,553,807,692,447,307,89,186,1071,103,980,906,599,1822,44,259,61,2636,1002,324,18,546 -0.43919996831517205,0.5636060512556167,0.8533559354124849,-0.05052375805598644,0.5636060512556167,0.30691434248850596,0.41136873678446767,0.7108269558541094,1.058987402257529,2.6583280208911844,1.6639450277501382,0.14549770029311399,2.40057096317167,0.1999552233330087,0.2537554699892711,0.5134346459158582,-0.19602066046695343,3.34039786005235,1.2555985905367433,3.161755509768943,-0.5659738392609449,0.1999552233330087,1.014100175743301,4.015494309311654,0.588482059091134 3367 Metal ion transport 24 89 3.032468816183087 0.0024256215800435 Q658P3,Q9H0U3,P46934,P50570,Q6P4Q7,Q96PU5,P21796,O76024,O14936,Q99996,P46939,O43707,Q15043,P16615,O00429,Q96GC9,P30536,P02786,O15173,P42858,Q9HD20,O95202,P27105,O75844 Processes and pathways GO Biological process msigdb_gobp 129,387,262,264,400,268,13,393,277,160,413,410,293,290,300,310,191,200,74,344,115,123,124,127 300,2363,277,74,410,2303,1015,2807,1862,2595,127,393,123,2426,200,1870,610,1531,2370,1655,807,1658,1534,1942,290,772,1181,436,3012,13,1183,124,3070,612,191,2491,613,742,3195,344,2552,262,413,264,2608,1126,2322,850,852,1808,3158,934,817,1355,1076,1889,2444,2499,1890,1815,821,1891,1554,293,2336,129,400,1029,1758,534,1692,1493,1090,1038,310,2739,268,160,1376,387,2741,1002,115,2162,1579,1847,2641,1521,734 1.081263578277897,-0.43919996831517205,1.1474357022138544,2.9317872528718985,0.7826588994764823,-0.40806438662984673,0.17280963840827135,-0.6964784202356398,-0.22570012371921228,-0.5659738392609449,2.16231565108635,0.8299141117114622,2.19713106377011,-0.4705554931571856,1.5851890116525102,-0.22570012371921228,0.488136037900703,-0.07924492702588042,-0.43919996831517205,-0.1372495529245524,0.30691434248850596,-0.1372495529245524,-0.07924492702588042,-0.25557908848123395,1.1034296234289172,0.3332580754721944,0.09036639678564706,0.7348993205919421,-0.8652075817496219,4.220028343416946,0.09036639678564706,2.19713106377011,-0.9345419567612725,0.488136037900703,1.6247393272059847,-0.5021341373910327,0.488136037900703,0.3594471701790773,-1.112787329154505,0.9459148854023514,-0.5339391468977894,1.2341735778065615,0.7826588994764823,1.2126457954814382,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.2804141068248859,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,0.30691434248850596,0.0063684354015670136,0.14549770029311399,-0.22570012371921228,-0.4705554931571856,-0.5021341373910327,-0.22570012371921228,-0.19602066046695343,0.30691434248850596,-0.22570012371921228,-0.07924492702588042,1.1034296234289172,-0.40806438662984673,2.16231565108635,0.8299141117114622,0.17280963840827135,-0.16653801380920247,0.588482059091134,-0.1372495529245524,-0.05052375805598644,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,1.8736785287250628,0.0063684354015670136,0.8533559354124849,-0.6307459142786708,0.1999552233330087,2.283013353361886,-0.31594654169938047,-0.07924492702588042,-0.19602066046695343,-0.5659738392609449,-0.05052375805598644,0.3854834577363446 3367 Splenomegaly 35 95 3.0312224068968354 0.0024356576680453 P15586,Q658P3,Q9H0U3,Q14108,P21964,Q14739,P83436,P51798,Q10713,Q96A33,Q9NZJ7,O14936,P10253,P28070,Q96RL7,Q9NZ08,P16278,Q8NBM4,Q6NUQ1,Q15904,P01889,P04066,P07602,P61916,Q15392,Q13510,Q96HY6,P54802,O15118,O00754,Q16625,P16930,P04062,P28288,Q15833 Drugs and Diseases Human Phenotype Ontology msigdb_hp 128,129,387,5,396,266,517,516,398,274,276,277,163,36,297,168,41,425,424,173,302,184,65,197,76,78,342,83,85,480,242,243,118,372,501 2171,735,480,1452,277,85,2922,1654,1591,3008,515,2924,1939,2103,302,805,118,184,3212,928,3087,1795,3088,65,163,692,1658,2654,2599,1534,3214,893,128,41,243,2655,1537,396,1458,2764,36,372,2603,570,2187,3121,3354,1349,743,1124,1292,516,2258,2193,83,3332,197,517,2266,2396,398,696,78,1304,5,266,76,1307,2617,501,173,242,129,424,601,3316,425,1982,2410,3053,274,1318,342,726,297,630,1916,387,2996,2639,2745,168,276,2643,3063 -0.34644068419145774,0.3594471701790773,0.6622900003005412,-0.05052375805598644,1.1474357022138544,2.7359582136753127,-0.7969425638483784,-0.1372495529245524,-0.10815269963874782,-0.8652075817496219,0.6132203653820887,-0.7969425638483784,-0.25557908848123395,-0.31594654169938047,1.081263578277897,0.30691434248850596,2.248856101291637,1.6639450277501382,-1.1493154316371736,0.22693649856222178,-0.969620885690122,-0.19602066046695343,-0.969620885690122,3.0911332595741183,1.8362643641609107,0.41136873678446767,-0.1372495529245524,-0.5982416058990344,-0.5659738392609449,-0.07924492702588042,-1.1493154316371736,0.2537554699892711,2.16231565108635,3.367269068562799,1.3192668476331657,-0.5982416058990344,-0.07924492702588042,0.8299141117114622,-0.05052375805598644,-0.6634903102109926,3.473195069920084,0.8766756507402944,-0.5659738392609449,0.5385907773537494,-0.34644068419145774,-1.004980242603473,-1.951622338591048,0.0063684354015670136,0.3594471701790773,0.11801732694304702,0.034544176031171075,0.6132203653820887,-0.37714563952921315,-0.34644068419145774,2.7513259355917703,-1.6129965081754174,1.605007630123358,0.6132203653820887,-0.37714563952921315,-0.43919996831517205,0.8299141117114622,0.41136873678446767,2.8724277004854066,0.034544176031171075,4.744465578955981,1.2126457954814382,2.8873405559171093,0.034544176031171075,-0.5659738392609449,0.6378225083090472,1.722120594018782,1.3402905479186136,2.16231565108635,0.7588428378146155,0.5134346459158582,-1.5322507832020744,0.7588428378146155,-0.25557908848123395,-0.43919996831517205,-0.8997389788237078,1.1692778855749448,0.034544176031171075,0.9687588066338071,0.3854834577363446,1.1034296234289172,0.488136037900703,-0.22570012371921228,0.8533559354124849,-0.8309434988946349,-0.5659738392609449,-0.6307459142786708,1.7795540517583925,1.1692778855749448,-0.5659738392609449,-0.8997389788237078 3367 Intrinsic component of mitochondrial membrane 17 39 3.0267772759168365 0.0024717600906911 Q9H3K2,O75431,Q9HC21,O14925,Q9BUR5,O60830,Q9Y512,Q99595,P12235,P50416,Q15070,Q16891,Q5XKP0,Q9Y2R0,Q13505,O96008,Q9NX63 Localization GO Cellular component msigdb_gocc 389,97,324,464,367,9,565,11,447,485,360,363,502,55,58,466,461 464,654,9,97,568,2649,1456,466,447,3220,485,1548,58,360,940,363,698,502,784,829,2573,2056,1493,11,1376,367,1378,389,1002,2960,324,1710,878,461,882,1048,55,734,565 0.6866243286062695,0.4371047742428398,4.521067264147013,2.4171181472402936,0.5385907773537494,-0.5982416058990344,-0.05052375805598644,0.6866243286062695,0.7108269558541094,-1.1493154316371736,0.6622900003005412,-0.07924492702588042,3.2036080031326675,0.8998745416649946,0.22693649856222178,0.8998745416649946,0.41136873678446767,0.6378225083090472,0.3332580754721944,0.30691434248850596,-0.5339391468977894,-0.28566029525923553,-0.05052375805598644,4.253245556056843,0.0063684354015670136,0.8998745416649946,0.0063684354015670136,0.8533559354124849,0.1999552233330087,-0.7969425638483784,1.014100175743301,-0.1372495529245524,0.2804141068248859,0.7108269558541094,0.2804141068248859,0.17280963840827135,3.231297118912164,0.3854834577363446,0.5636060512556167 3367 Cis golgi network 7 14 3.012921500759582 0.0025874583784708 Q99996,P24390,Q16706,Q86VS8,Q9NPR9,O00461,Q08379 Localization GO Cellular component msigdb_gocc 160,2,294,364,20,53,287 53,1453,2,639,437,287,782,294,364,1696,1257,160,20,1931 3.245078698171657,-0.05052375805598644,5.106453588871854,0.46269330605308917,0.7348993205919421,1.1254866370979533,0.3332580754721944,1.1034296234289172,0.8998745416649946,-0.1372495529245524,0.06254274771127205,1.8736785287250628,3.897780748473081,-0.22570012371921228 3367 Cholesterol binding 7 14 3.0124365064661647 0.0025915964441931 P30536,Q14108,P61916,Q14849,P21796,P45880,O15118 Functions GO Molecular function msigdb_gomf 191,5,197,6,13,19,85 85,2023,1655,13,2929,191,308,19,197,5,6,491,761,582 2.7359582136753127,-0.28566029525923553,-0.1372495529245524,4.220028343416946,-0.7969425638483784,1.6247393272059847,1.058987402257529,3.9215673900004977,1.605007630123358,4.744465578955981,4.664482621298005,0.6622900003005412,0.3594471701790773,0.5385907773537494 3367 Liposaccharide metabolic process 8 16 3.011507897323393 0.0025995364069619 P16278,P06280,P17900,P06865,Q8NBX0,P04062,P04066,Q9H490 Processes and pathways GO Biological process msigdb_gobp 41,139,169,81,114,118,184,289 1654,118,184,139,81,1064,41,169,2396,519,114,1497,1092,628,379,289 -0.1372495529245524,2.248856101291637,1.6639450277501382,2.074084118777206,2.781905953857426,0.14549770029311399,3.367269068562799,1.7413465847323417,-0.43919996831517205,0.6132203653820887,2.283013353361886,-0.05052375805598644,0.14549770029311399,0.488136037900703,0.8766756507402944,1.1254866370979533 3367 Sterol binding 7 17 3.006315085758453 0.0026443483222713 P30536,Q14108,P61916,Q14849,P21796,P45880,O15118 Functions GO Molecular function msigdb_gomf 191,5,197,6,13,19,85 85,2023,1655,13,2314,2929,191,308,19,197,5,6,1096,1990,491,761,582 2.7359582136753127,-0.28566029525923553,-0.1372495529245524,4.220028343416946,-0.40806438662984673,-0.7969425638483784,1.6247393272059847,1.058987402257529,3.9215673900004977,1.605007630123358,4.744465578955981,4.664482621298005,0.14549770029311399,-0.25557908848123395,0.6622900003005412,0.3594471701790773,0.5385907773537494 3367 Inorganic anion transport 7 20 3.0016354940767447 0.0026853350514208 P30536,Q9UHG3,Q9C0H2,P21796,P08183,Q9UBX3,P45880 Processes and pathways GO Biological process msigdb_gobp 191,37,72,13,110,18,19 2645,738,110,2180,13,191,19,516,1887,2322,1548,980,293,2340,72,1213,18,37,548,2536 -0.5982416058990344,0.3594471701790773,2.2999956417932186,-0.34644068419145774,4.220028343416946,1.6247393272059847,3.9215673900004977,0.6132203653820887,-0.22570012371921228,-0.40806438662984673,-0.07924492702588042,0.1999552233330087,1.1034296234289172,-0.40806438662984673,2.9465065973455364,0.09036639678564706,4.015494309311654,3.473195069920084,0.588482059091134,-0.5021341373910327 3367 Abnormal retinal artery morphology 8 20 2.9957218879672127 0.0027379602171799 P10619,P07602,P16278,P17900,Q9Y4P3,Q13510,P06865,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 190,65,41,169,205,78,81,276 1277,2540,81,65,1064,190,2758,41,169,396,1661,2258,1412,78,1426,1982,2410,276,958,205 0.034544176031171075,-0.5339391468977894,2.781905953857426,3.0911332595741183,0.14549770029311399,1.6247393272059847,-0.6634903102109926,3.367269068562799,1.7413465847323417,0.8299141117114622,-0.1372495529245524,-0.37714563952921315,-0.02198676428679048,2.8724277004854066,-0.02198676428679048,-0.25557908848123395,-0.43919996831517205,1.1692778855749448,0.22693649856222178,1.5851890116525102 3367 Receptor mediated endocytosis 12 57 2.992608231205798 0.0027660456990894 O75955,P11717,Q14108,P46934,P05067,P50570,P41440,P02786,Q5VW38,P20645,P50897,Q9Y5X1 Processes and pathways GO Biological process msigdb_gobp 162,217,5,262,90,264,186,200,16,185,26,30 1225,2538,495,1935,1653,1527,162,1281,1062,200,90,1531,2370,554,1594,217,973,773,185,2601,556,639,186,810,262,264,26,813,781,3126,1546,1810,1956,817,1961,1889,1476,2042,2446,2043,5,1965,1745,3224,3277,16,1905,1627,1694,835,1328,2748,3229,428,282,1647,30 0.06254274771127205,-0.5339391468977894,0.6378225083090472,-0.25557908848123395,-0.1372495529245524,-0.07924492702588042,1.8550102756937976,0.034544176031171075,0.14549770029311399,1.5851890116525102,2.595251590463738,-0.07924492702588042,-0.43919996831517205,0.5636060512556167,-0.10815269963874782,1.5050295510613063,0.1999552233330087,0.3332580754721944,1.6639450277501382,-0.5659738392609449,0.5636060512556167,0.46269330605308917,1.6639450277501382,0.30691434248850596,1.2341735778065615,1.2126457954814382,3.6904275097045454,0.30691434248850596,0.3332580754721944,-1.004980242603473,-0.07924492702588042,-0.19602066046695343,-0.25557908848123395,0.30691434248850596,-0.25557908848123395,-0.22570012371921228,-0.05052375805598644,-0.28566029525923553,-0.4705554931571856,-0.28566029525923553,4.744465578955981,-0.25557908848123395,-0.16653801380920247,-1.1493154316371736,-1.3366301135330916,4.130251742479455,-0.22570012371921228,-0.10815269963874782,-0.1372495529245524,0.30691434248850596,0.034544176031171075,-0.6307459142786708,-1.1493154316371736,0.7588428378146155,1.1474357022138544,-0.10815269963874782,3.614933961940769 3367 Endocytic vesicle 30 82 2.9901358562974893 0.0027885339229603 Q9UNK0,Q14108,Q9H1C4,P11279,P08670,P50570,O14964,Q9UKG1,Q9Y4G8,Q5KU26,P01889,P09496,O00461,P20645,Q8WTV0,O43752,P02786,O15400,Q14254,P13473,Q9Y487,P04439,P11717,Q93050,Q12846,P10321,Q16625,P33176,Q14C86,P42345 Localization GO Cellular component msigdb_gocc 526,5,133,261,263,264,392,547,564,171,302,554,53,185,60,189,200,446,338,210,215,333,217,92,345,481,242,613,617,498 1275,1855,2538,53,392,446,1588,189,3282,2877,2367,1281,1062,302,200,333,969,263,554,1594,481,971,261,217,210,1118,773,185,2764,2885,613,498,264,976,977,1019,3152,813,1606,2324,933,2259,746,3126,1956,817,1677,1476,345,1078,2042,821,1891,5,338,617,1360,3277,1684,242,2206,171,700,2621,2512,828,60,2456,92,835,1210,2528,133,649,547,2296,1520,526,215,564,1164,1647 0.034544176031171075,-0.22570012371921228,-0.5339391468977894,3.245078698171657,0.8299141117114622,0.7108269558541094,-0.10815269963874782,1.6247393272059847,-1.37506621536203,-0.7632007073119792,-0.43919996831517205,0.034544176031171075,0.14549770029311399,1.081263578277897,1.5851890116525102,0.9687588066338071,0.1999552233330087,1.2126457954814382,0.5636060512556167,-0.10815269963874782,0.6622900003005412,0.1999552233330087,1.2341735778065615,1.5050295510613063,1.5452878774447738,0.11801732694304702,0.3332580754721944,1.6639450277501382,-0.6634903102109926,-0.7632007073119792,0.488136037900703,0.6378225083090472,1.2126457954814382,0.1999552233330087,0.1999552233330087,0.17280963840827135,-1.0406246148817728,0.30691434248850596,-0.10815269963874782,-0.40806438662984673,0.22693649856222178,-0.37714563952921315,0.3594471701790773,-1.004980242603473,-0.25557908848123395,0.30691434248850596,-0.1372495529245524,-0.05052375805598644,0.9459148854023514,0.14549770029311399,-0.28566029525923553,0.30691434248850596,-0.22570012371921228,4.744465578955981,0.9687588066338071,0.488136037900703,0.0063684354015670136,-1.3366301135330916,-0.1372495529245524,1.3402905479186136,-0.34644068419145774,1.7413465847323417,0.41136873678446767,-0.5659738392609449,-0.5021341373910327,0.30691434248850596,3.1896999455248927,-0.4705554931571856,2.5793442451134623,0.30691434248850596,0.09036639678564706,-0.5021341373910327,2.12722970929693,0.46269330605308917,0.588482059091134,-0.37714563952921315,-0.05052375805598644,0.6132203653820887,1.525203768425511,0.5636060512556167,0.11801732694304702,-0.10815269963874782 3367 Lipid homeostasis 10 23 2.981524675612051 0.0028681693161096 Q9NQC3,P61916,Q5BJF2,Q15067,P34913,Q9Y6C9,O15254,O15118,O15260,Q8WTV0 Processes and pathways GO Biological process msigdb_gobp 96,197,7,232,207,306,149,85,121,60 1717,85,149,121,1170,2026,2317,207,308,197,3352,519,232,7,598,1029,60,2143,1378,96,711,2229,306 -0.16653801380920247,2.7359582136753127,1.9840930614703445,2.214438638015626,0.09036639678564706,-0.28566029525923553,-0.40806438662984673,1.5652826911718993,1.058987402257529,1.605007630123358,-1.907862431915821,0.6132203653820887,1.402777585756001,4.552178889851971,0.5134346459158582,0.17280963840827135,3.1896999455248927,-0.31594654169938047,0.0063684354015670136,2.433605013064534,0.41136873678446767,-0.34644068419145774,1.081263578277897 3367 Cation transmembrane transport 30 104 2.969187453886251 0.0029858838772407 Q9H0U3,O43772,P46934,P50570,Q6P4Q7,Q96PU5,P21796,P00403,Q70HW3,P24539,Q99996,P46939,O43707,P13073,Q9UDW1,Q15043,P16615,O75964,Q96GC9,P20020,P06576,Q9HC21,Q13423,P30825,P05067,P42858,Q9HD20,P25705,O95202,P27105 Processes and pathways GO Biological process msigdb_gobp 387,134,262,264,400,268,13,145,22,411,160,413,410,167,40,293,290,45,310,436,435,324,71,89,90,344,115,244,123,124 1389,2363,410,134,2303,1015,2096,2807,2595,1938,45,123,2426,145,610,90,553,1531,435,2370,2549,1655,807,970,1872,1534,447,167,290,1181,436,1797,1537,2377,3012,13,411,244,124,3070,612,3091,2491,89,3038,3195,2318,1539,2976,344,262,413,484,3321,264,2608,1126,2322,1073,1127,746,852,1808,3158,934,1548,1076,1889,1890,1815,71,1891,1554,293,3277,906,400,1029,22,1758,534,1692,1493,1090,1038,310,2739,268,3280,1507,160,1376,387,2741,2636,1002,324,115,40,2162,585,1579,1521,734 -0.02198676428679048,-0.43919996831517205,0.7826588994764823,2.1095839500852342,-0.40806438662984673,0.17280963840827135,-0.31594654169938047,-0.6964784202356398,-0.5659738392609449,-0.25557908848123395,3.286174597616811,2.19713106377011,-0.4705554931571856,2.002235460610414,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,0.7348993205919421,-0.43919996831517205,-0.5339391468977894,-0.1372495529245524,0.30691434248850596,0.1999552233330087,-0.22570012371921228,-0.07924492702588042,0.7108269558541094,1.7795540517583925,1.1034296234289172,0.09036639678564706,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8652075817496219,4.220028343416946,0.7826588994764823,1.3192668476331657,2.19713106377011,-0.9345419567612725,0.488136037900703,-0.969620885690122,-0.5021341373910327,2.6583280208911844,-0.8997389788237078,-1.112787329154505,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,0.9459148854023514,1.2341735778065615,0.7826588994764823,0.6622900003005412,-1.5724386516725661,1.2126457954814382,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,-0.07924492702588042,0.14549770029311399,-0.22570012371921228,-0.22570012371921228,-0.19602066046695343,2.9465065973455364,-0.22570012371921228,-0.07924492702588042,1.1034296234289172,-1.3366301135330916,0.2537554699892711,0.8299141117114622,0.17280963840827135,3.8256681593087887,-0.16653801380920247,0.588482059091134,-0.1372495529245524,-0.05052375805598644,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,-1.3366301135330916,-0.05052375805598644,1.8736785287250628,0.0063684354015670136,0.8533559354124849,-0.6307459142786708,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,3.380645404831543,-0.31594654169938047,0.5385907773537494,-0.07924492702588042,-0.05052375805598644,0.3854834577363446 3367 Inorganic ion transmembrane transport 32 99 2.9663738981395493 0.0030133390475755 Q9H0U3,P46934,P50570,Q6P4Q7,P51798,P21796,Q96PU5,Q9UBX3,P00403,Q8IYU8,P24539,Q99996,P46939,O43707,Q9UHG3,P13073,Q9UDW1,Q15043,P16615,O75964,P05141,Q96GC9,P20020,P06576,Q13423,P12235,P42858,P47985,Q9HD20,P25705,O95202,P27105 Processes and pathways GO Biological process msigdb_gobp 387,262,264,400,516,13,268,18,145,534,411,160,413,410,37,167,40,293,290,45,553,310,436,435,71,447,344,484,115,244,123,124 1389,2363,410,2303,1015,2096,2807,2595,1938,45,123,2426,145,610,553,1531,435,2370,1655,807,970,1872,1534,447,167,290,1181,436,1797,1537,2377,3012,13,411,244,124,3070,612,3091,2491,3038,3195,2318,1539,2976,344,262,413,484,3321,264,516,2608,1126,2322,1073,1127,746,852,1808,3158,934,1548,980,1076,1889,1890,1815,71,1891,1554,293,400,1029,1758,534,1692,1493,1090,1038,310,2739,268,3280,1507,160,1376,387,2741,2636,115,18,40,2162,37,585,1579,1521,734 -0.02198676428679048,-0.43919996831517205,0.7826588994764823,-0.40806438662984673,0.17280963840827135,-0.31594654169938047,-0.6964784202356398,-0.5659738392609449,-0.25557908848123395,3.286174597616811,2.19713106377011,-0.4705554931571856,2.002235460610414,0.488136037900703,0.5636060512556167,-0.07924492702588042,0.7348993205919421,-0.43919996831517205,-0.1372495529245524,0.30691434248850596,0.1999552233330087,-0.22570012371921228,-0.07924492702588042,0.7108269558541094,1.7795540517583925,1.1034296234289172,0.09036639678564706,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8652075817496219,4.220028343416946,0.7826588994764823,1.3192668476331657,2.19713106377011,-0.9345419567612725,0.488136037900703,-0.969620885690122,-0.5021341373910327,-0.8997389788237078,-1.112787329154505,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,0.9459148854023514,1.2341735778065615,0.7826588994764823,0.6622900003005412,-1.5724386516725661,1.2126457954814382,0.6132203653820887,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.3594471701790773,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,-0.07924492702588042,0.1999552233330087,0.14549770029311399,-0.22570012371921228,-0.22570012371921228,-0.19602066046695343,2.9465065973455364,-0.22570012371921228,-0.07924492702588042,1.1034296234289172,0.8299141117114622,0.17280963840827135,-0.16653801380920247,0.588482059091134,-0.1372495529245524,-0.05052375805598644,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,-1.3366301135330916,-0.05052375805598644,1.8736785287250628,0.0063684354015670136,0.8533559354124849,-0.6307459142786708,-0.5659738392609449,2.283013353361886,4.015494309311654,3.380645404831543,-0.31594654169938047,3.473195069920084,0.5385907773537494,-0.07924492702588042,-0.05052375805598644,0.3854834577363446 3367 Metal ion homeostasis 21 71 2.9662089641326737 0.0030149556257292 P09601,P30519,Q658P3,Q6P4Q7,Q96PU5,O76024,P51572,Q96A33,Q15043,P16615,Q15904,Q8N511,P02786,Q96TC7,Q9Y487,Q8NE01,P05067,P42858,Q16891,Q9HD20,O95202 Processes and pathways GO Biological process msigdb_gobp 0,1,129,400,268,393,273,274,293,290,173,48,200,343,215,351,90,344,363,115,123 2171,1452,654,2303,593,1015,568,3253,393,123,926,200,3255,1870,610,90,1064,1655,1656,0,1942,1118,290,1181,436,774,3070,2764,612,1,2491,2976,344,273,1126,2322,746,1808,3158,934,1815,3290,2042,1891,1359,293,3277,173,363,129,400,1029,1758,534,48,351,1493,868,1090,274,2739,268,343,1376,1512,115,1579,1581,215,734,567 -0.34644068419145774,-0.05052375805598644,0.4371047742428398,-0.40806438662984673,0.5134346459158582,0.17280963840827135,0.5385907773537494,-1.2607479309781038,0.8299141117114622,2.19713106377011,0.22693649856222178,1.5851890116525102,-1.2607479309781038,-0.22570012371921228,0.488136037900703,2.595251590463738,0.14549770029311399,-0.1372495529245524,-0.1372495529245524,5.77073025593568,-0.25557908848123395,0.11801732694304702,1.1034296234289172,0.09036639678564706,0.7348993205919421,0.3332580754721944,-0.9345419567612725,-0.6634903102109926,0.488136037900703,5.215090048676801,-0.5021341373910327,-0.8309434988946349,0.9459148854023514,1.1692778855749448,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,-0.19602066046695343,-1.4138401674883982,-0.28566029525923553,-0.22570012371921228,0.0063684354015670136,1.1034296234289172,-1.3366301135330916,1.722120594018782,0.8998745416649946,2.16231565108635,0.8299141117114622,0.17280963840827135,-0.16653801380920247,0.588482059091134,3.286174597616811,0.9459148854023514,-0.05052375805598644,0.2804141068248859,0.14549770029311399,1.1692778855749448,-0.6307459142786708,1.2126457954814382,0.9687588066338071,0.0063684354015670136,-0.05052375805598644,2.283013353361886,-0.07924492702588042,-0.07924492702588042,1.525203768425511,0.3854834577363446,0.5636060512556167 3367 Glycosyltransferase activity 12 44 2.963614724122025 0.0030404870137041 O43505,P04843,Q6ZXV5,Q10472,Q8TCJ2,P06865,P43490,P04062,Q2TAA5,P46977,Q86SF2,Q13126 Functions GO Molecular function msigdb_gomf 195,254,267,208,341,81,335,118,248,188,317,95 2093,2018,195,1526,1654,2544,2103,2927,118,254,1173,1117,81,1064,2652,2374,2654,1873,1179,1662,335,1800,188,854,1416,1357,664,208,95,248,267,1978,1624,317,2346,341,2143,378,630,1918,1440,2697,1006,1107 -0.31594654169938047,-0.28566029525923553,1.605007630123358,-0.07924492702588042,-0.1372495529245524,-0.5339391468977894,-0.31594654169938047,-0.7969425638483784,2.248856101291637,1.2555985905367433,0.09036639678564706,0.11801732694304702,2.781905953857426,0.14549770029311399,-0.5982416058990344,-0.43919996831517205,-0.5982416058990344,-0.22570012371921228,0.09036639678564706,-0.1372495529245524,0.9687588066338071,-0.19602066046695343,1.6443848730963768,0.2804141068248859,-0.02198676428679048,0.0063684354015670136,0.4371047742428398,1.5652826911718993,2.4663995632740083,1.2981442560194676,1.2126457954814382,-0.25557908848123395,-0.10815269963874782,1.0365999791862452,-0.40806438662984673,0.9687588066338071,-0.31594654169938047,0.8766756507402944,0.488136037900703,-0.22570012371921228,-0.02198676428679048,-0.5982416058990344,0.1999552233330087,0.14549770029311399 3367 Basal part of cell 15 47 2.9620862399508545 0.0030556218586939 Q12846,Q99808,O75955,P35613,P53985,Q15043,Q6P4Q7,P02786,Q03001,Q14254,P42785,O14936,P30825,P41440,P19022 Localization GO Cellular component msigdb_gocc 345,259,162,165,103,293,400,200,423,338,21,277,89,186,286 1275,1855,277,2366,162,1229,200,2484,610,2370,807,1065,692,1658,2109,973,3355,286,436,611,89,742,165,186,21,103,1126,2322,1735,423,819,1476,345,1815,1078,858,1965,338,293,906,400,1255,1037,1505,2690,259,2079 0.034544176031171075,-0.22570012371921228,1.1474357022138544,-0.43919996831517205,1.8550102756937976,0.06254274771127205,1.5851890116525102,-0.5021341373910327,0.488136037900703,-0.43919996831517205,0.30691434248850596,0.14549770029311399,0.41136873678446767,-0.1372495529245524,-0.31594654169938047,0.1999552233330087,-1.9957969029261853,1.1254866370979533,0.7348993205919421,0.488136037900703,2.6583280208911844,0.3594471701790773,1.7985369233817154,1.6639450277501382,3.8498324746709085,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.16653801380920247,0.7588428378146155,0.30691434248850596,-0.05052375805598644,0.9459148854023514,-0.19602066046695343,0.14549770029311399,0.2804141068248859,-0.25557908848123395,0.9687588066338071,1.1034296234289172,0.2537554699892711,0.8299141117114622,0.06254274771127205,0.17280963840827135,-0.05052375805598644,-0.5982416058990344,1.2555985905367433,-0.28566029525923553 3367 Cellular ion homeostasis 28 79 2.949417454261058 0.0031837360928066 P09601,Q96PU5,O76024,P51572,Q96A33,P50897,Q8IYU8,Q15043,P16615,Q15904,Q8N511,P20020,P06576,Q9UI12,O75880,P02786,Q96TC7,Q9Y487,P05067,O60826,Q93050,P42858,O75503,Q92544,P28161,Q16891,Q9HD20,O95202 Processes and pathways GO Biological process msigdb_gobp 0,268,393,273,274,26,534,293,290,173,48,436,435,585,568,200,343,215,90,593,92,344,102,489,612,363,115,123 2171,1452,2363,654,2303,593,1015,102,568,3253,393,123,926,891,200,610,90,435,1064,1655,1656,0,2180,2881,1942,1118,290,1181,436,774,2763,3070,2764,612,2431,2491,2976,344,26,1019,273,1126,2322,746,1808,3158,934,1417,3290,1891,1359,293,3277,173,363,1029,1758,534,48,1493,868,1090,489,92,274,1318,2739,268,343,1376,1512,115,2162,585,1579,1581,215,734,2536 -0.34644068419145774,-0.05052375805598644,-0.43919996831517205,0.4371047742428398,-0.40806438662984673,0.5134346459158582,0.17280963840827135,2.40057096317167,0.5385907773537494,-1.2607479309781038,0.8299141117114622,2.19713106377011,0.22693649856222178,0.2537554699892711,1.5851890116525102,0.488136037900703,2.595251590463738,0.7348993205919421,0.14549770029311399,-0.1372495529245524,-0.1372495529245524,5.77073025593568,-0.34644068419145774,-0.7632007073119792,-0.25557908848123395,0.11801732694304702,1.1034296234289172,0.09036639678564706,0.7348993205919421,0.3332580754721944,-0.6634903102109926,-0.9345419567612725,-0.6634903102109926,0.488136037900703,-0.4705554931571856,-0.5021341373910327,-0.8309434988946349,0.9459148854023514,3.6904275097045454,0.17280963840827135,1.1692778855749448,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,-0.02198676428679048,-1.4138401674883982,-0.22570012371921228,0.0063684354015670136,1.1034296234289172,-1.3366301135330916,1.722120594018782,0.8998745416649946,0.17280963840827135,-0.16653801380920247,0.588482059091134,3.286174597616811,-0.05052375805598644,0.2804141068248859,0.14549770029311399,0.6622900003005412,2.5793442451134623,1.1692778855749448,0.034544176031171075,-0.6307459142786708,1.2126457954814382,0.9687588066338071,0.0063684354015670136,-0.05052375805598644,2.283013353361886,-0.31594654169938047,0.5385907773537494,-0.07924492702588042,-0.07924492702588042,1.525203768425511,0.3854834577363446,-0.5021341373910327 3367 Mitochondrial protein import 18 30 2.94501514077506 0.0032293885930685 O75431,Q9NS69,O14925,O75746,O60830,O43615,Q99595,Q10713,P21796,P12235,P25705,Q9UJS0,P06576,P12236,Q5JRX3,Q13505,O96008,Q9NX63 Processes and pathways Reactome Pathways msigdb_reactome 97,3,464,381,9,513,11,398,13,447,244,546,435,307,375,58,466,461 464,513,9,3168,97,2595,381,2649,466,435,970,3034,447,307,13,244,3220,398,58,826,375,11,2862,2797,3,461,546,733,565,1853 0.6866243286062695,0.6132203653820887,4.521067264147013,-1.0765587039609845,2.4171181472402936,-0.5659738392609449,0.8533559354124849,-0.5982416058990344,0.6866243286062695,0.7348993205919421,0.1999552233330087,-0.8997389788237078,0.7108269558541094,1.058987402257529,4.220028343416946,1.3192668476331657,-1.1493154316371736,0.8299141117114622,3.2036080031326675,0.30691434248850596,0.8766756507402944,4.253245556056843,-0.7297139540963061,-0.6634903102109926,4.832811783410612,0.7108269558541094,0.588482059091134,0.3854834577363446,0.5636060512556167,-0.19602066046695343 3367 Abnormality of head blood vessel 8 22 2.941948954786566 0.0032615368452912 P10619,P07602,P16278,P17900,Q9Y4P3,Q13510,P06865,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 190,65,41,169,205,78,81,276 1276,1277,2540,81,65,1064,190,2758,41,169,396,1661,533,2258,1412,78,1426,1982,2410,276,958,205 0.034544176031171075,0.034544176031171075,-0.5339391468977894,2.781905953857426,3.0911332595741183,0.14549770029311399,1.6247393272059847,-0.6634903102109926,3.367269068562799,1.7413465847323417,0.8299141117114622,-0.1372495529245524,0.588482059091134,-0.37714563952921315,-0.02198676428679048,2.8724277004854066,-0.02198676428679048,-0.25557908848123395,-0.43919996831517205,1.1692778855749448,0.22693649856222178,1.5851890116525102 3367 Membrane lipid biosynthetic process 11 22 2.931357744026488 0.0033748389331664 O15269,Q96G23,Q06136,Q13510,Q8NBX0,Q99805,P04062,O95470,P27544,Q9H490,Q9P035 Processes and pathways GO Biological process msigdb_gobp 220,66,77,78,114,379,118,250,467,289,260 220,965,1654,250,118,2314,467,2396,77,519,78,698,114,1497,1092,66,628,379,289,796,260,1155 1.4644074828289309,0.1999552233330087,-0.1372495529245524,1.276921824455599,2.248856101291637,-0.40806438662984673,0.6866243286062695,-0.43919996831517205,2.8724277004854066,0.6132203653820887,2.8724277004854066,0.41136873678446767,2.283013353361886,-0.05052375805598644,0.14549770029311399,3.0911332595741183,0.488136037900703,0.8766756507402944,1.1254866370979533,0.3332580754721944,1.2555985905367433,0.11801732694304702 3367 Nucleobase containing compound transmembrane transporter activity 10 13 2.927370877183207 0.003418409723759 Q99808,Q9HC21,P12235,Q8TB61,Q9BSK2,O43808,P05141,P12236,P41440,Q9H2D1 Functions GO Molecular function msigdb_gomf 259,324,447,44,209,549,553,307,186,61 1388,549,553,447,307,186,1293,599,44,259,209,61,324 -0.02198676428679048,0.5636060512556167,0.5636060512556167,0.7108269558541094,1.058987402257529,1.6639450277501382,0.034544176031171075,0.5134346459158582,3.34039786005235,1.2555985905367433,1.5652826911718993,3.161755509768943,1.014100175743301 3367 Aminoglycan metabolic process 6 13 2.9236397475630045 0.0034596488998028 P15586,P16278,P06865,P54802,Q7LGA3,P04066 Processes and pathways GO Biological process msigdb_gobp 128,41,81,83,152,184 195,2594,1062,184,81,1064,128,41,83,817,1963,152,378 1.605007630123358,-0.5659738392609449,0.14549770029311399,1.6639450277501382,2.781905953857426,0.14549770029311399,2.16231565108635,3.367269068562799,2.7513259355917703,0.30691434248850596,-0.25557908848123395,1.9840930614703445,0.8766756507402944 3367 Lipid droplet 10 32 2.908368675379662 0.0036331973621364 P48449,Q07065,Q96RL7,P51572,Q9H6V9,Q8NBQ5,Q01105,Q8NBX0,O43760,Q99720 Localization GO Cellular component msigdb_gocc 98,131,297,273,50,403,181,114,216,28 2478,216,2302,1394,1171,2808,2713,2370,98,977,1019,273,1803,2818,181,131,1817,1247,2822,418,403,114,1367,1257,1368,297,28,761,50,1218,2297,1224 -0.5021341373910327,1.5050295510613063,-0.40806438662984673,-0.02198676428679048,0.09036639678564706,-0.6964784202356398,-0.6307459142786708,-0.43919996831517205,2.4171181472402936,0.1999552233330087,0.17280963840827135,1.1692778855749448,-0.19602066046695343,-0.6964784202356398,1.7028121530513547,2.144806762718082,-0.19602066046695343,0.06254274771127205,-0.6964784202356398,0.7826588994764823,0.8063488749900722,2.283013353361886,0.0063684354015670136,0.06254274771127205,0.0063684354015670136,1.1034296234289172,3.665401627508389,0.3594471701790773,3.286174597616811,0.09036639678564706,-0.37714563952921315,0.09036639678564706 3367 Intrinsic component of mitochondrial inner membrane 17 28 2.907594032850213 0.0036422082420495 Q9H3K2,O75431,O43819,Q9HC21,O14925,Q9BUR5,O75880,O60830,Q9Y512,Q99595,Q15070,Q16891,Q5XKP0,Q9Y2R0,Q13505,Q9NX63,Q53H12 Localization GO Cellular component msigdb_gocc 389,97,654,324,464,367,568,9,565,11,360,363,502,55,58,461,698 464,654,9,97,568,1456,3220,1548,58,360,940,363,698,502,784,1493,11,367,389,1002,2960,324,878,461,882,55,734,565 0.6866243286062695,0.4371047742428398,4.521067264147013,2.4171181472402936,0.5385907773537494,-0.05052375805598644,-1.1493154316371736,-0.07924492702588042,3.2036080031326675,0.8998745416649946,0.22693649856222178,0.8998745416649946,0.41136873678446767,0.6378225083090472,0.3332580754721944,-0.05052375805598644,4.253245556056843,0.8998745416649946,0.8533559354124849,0.1999552233330087,-0.7969425638483784,1.014100175743301,0.2804141068248859,0.7108269558541094,0.2804141068248859,3.231297118912164,0.3854834577363446,0.5636060512556167 3367 Cation transport 40 134 2.905548229373877 0.0036661034507341 Q658P3,Q99808,Q9H0U3,O43772,P46934,P50570,Q6P4Q7,Q96PU5,P21796,O76024,P00403,O14936,Q70HW3,P24539,Q99996,P46939,O43707,P13073,Q9UDW1,Q15043,P16615,O00429,O75964,Q96GC9,P20020,P06576,P30536,Q9HC21,Q13423,P02786,O15173,P80404,P30825,P05067,P42858,Q9HD20,P25705,O95202,P27105,O75844 Processes and pathways GO Biological process msigdb_gobp 129,259,387,134,262,264,400,268,13,393,145,277,22,411,160,413,410,167,40,293,290,300,45,310,436,435,191,324,71,200,74,211,89,90,344,115,244,123,124,127 300,1389,2363,277,74,410,134,549,2303,1015,2096,2807,1862,2595,127,1938,45,393,123,2426,145,200,1870,610,90,553,1531,435,2370,2549,1655,807,970,1872,1658,1534,447,167,1942,290,772,1181,436,1797,1537,2377,3012,13,411,1183,244,124,3070,612,3091,191,2491,89,3038,613,742,3195,2318,1539,2976,344,2552,262,413,484,3321,264,2608,1126,2322,1073,1127,850,746,852,1808,3158,934,211,1548,817,1355,1076,1889,2444,2499,1890,1815,71,821,1891,1554,293,3277,906,2336,129,400,1029,22,1758,534,1692,1493,1090,1038,310,2739,268,3280,1507,259,160,1376,387,2741,2636,1002,324,115,40,2162,585,1579,1847,2641,960,1521,734 1.081263578277897,-0.02198676428679048,-0.43919996831517205,1.1474357022138544,2.9317872528718985,0.7826588994764823,2.1095839500852342,0.5636060512556167,-0.40806438662984673,0.17280963840827135,-0.31594654169938047,-0.6964784202356398,-0.22570012371921228,-0.5659738392609449,2.16231565108635,-0.25557908848123395,3.286174597616811,0.8299141117114622,2.19713106377011,-0.4705554931571856,2.002235460610414,1.5851890116525102,-0.22570012371921228,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,0.7348993205919421,-0.43919996831517205,-0.5339391468977894,-0.1372495529245524,0.30691434248850596,0.1999552233330087,-0.22570012371921228,-0.1372495529245524,-0.07924492702588042,0.7108269558541094,1.7795540517583925,-0.25557908848123395,1.1034296234289172,0.3332580754721944,0.09036639678564706,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8652075817496219,4.220028343416946,0.7826588994764823,0.09036639678564706,1.3192668476331657,2.19713106377011,-0.9345419567612725,0.488136037900703,-0.969620885690122,1.6247393272059847,-0.5021341373910327,2.6583280208911844,-0.8997389788237078,0.488136037900703,0.3594471701790773,-1.112787329154505,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,0.9459148854023514,-0.5339391468977894,1.2341735778065615,0.7826588994764823,0.6622900003005412,-1.5724386516725661,1.2126457954814382,-0.5659738392609449,0.11801732694304702,-0.40806438662984673,0.14549770029311399,0.11801732694304702,0.2804141068248859,0.3594471701790773,0.2804141068248859,-0.19602066046695343,-1.0406246148817728,0.22693649856222178,1.525203768425511,-0.07924492702588042,0.30691434248850596,0.0063684354015670136,0.14549770029311399,-0.22570012371921228,-0.4705554931571856,-0.5021341373910327,-0.22570012371921228,-0.19602066046695343,2.9465065973455364,0.30691434248850596,-0.22570012371921228,-0.07924492702588042,1.1034296234289172,-1.3366301135330916,0.2537554699892711,-0.40806438662984673,2.16231565108635,0.8299141117114622,0.17280963840827135,3.8256681593087887,-0.16653801380920247,0.588482059091134,-0.1372495529245524,-0.05052375805598644,0.14549770029311399,0.17280963840827135,1.058987402257529,-0.6307459142786708,1.2126457954814382,-1.3366301135330916,-0.05052375805598644,1.2555985905367433,1.8736785287250628,0.0063684354015670136,0.8533559354124849,-0.6307459142786708,-0.5659738392609449,0.1999552233330087,1.014100175743301,2.283013353361886,3.380645404831543,-0.31594654169938047,0.5385907773537494,-0.07924492702588042,-0.19602066046695343,-0.5659738392609449,0.22693649856222178,-0.05052375805598644,0.3854834577363446 3367 Slc mediated transmembrane transport 8 19 2.885650433330789 0.0039060573866385 Q99808,P35613,P53985,Q15043,Q8TB61,Q9UBX3,Q70HW3,P30825 Processes and pathways Reactome Pathways msigdb_reactome 259,165,103,293,44,18,22,89 553,807,692,447,307,2491,89,165,2251,103,2322,293,906,1822,22,44,259,2636,18 0.5636060512556167,0.30691434248850596,0.41136873678446767,0.7108269558541094,1.058987402257529,-0.5021341373910327,2.6583280208911844,1.7985369233817154,-0.37714563952921315,2.40057096317167,-0.40806438662984673,1.1034296234289172,0.2537554699892711,-0.19602066046695343,3.8256681593087887,3.34039786005235,1.2555985905367433,-0.5659738392609449,4.015494309311654 3367 External side of plasma membrane 7 22 2.865212883257073 0.0041672898569302 O75955,P02786,P42892,P08183,P55899,O96005,P41440 Localization GO Cellular component msigdb_gocc 162,200,43,110,180,150,186 162,150,2307,200,2484,1531,1345,110,261,2109,1346,2764,186,43,2383,743,180,695,858,2206,1032,1581 1.8550102756937976,1.9840930614703445,-0.40806438662984673,1.5851890116525102,-0.5021341373910327,-0.07924492702588042,0.0063684354015670136,2.2999956417932186,1.2341735778065615,-0.31594654169938047,0.0063684354015670136,-0.6634903102109926,1.6639450277501382,3.34039786005235,-0.43919996831517205,0.3594471701790773,1.7028121530513547,0.41136873678446767,0.2804141068248859,-0.34644068419145774,0.17280963840827135,-0.07924492702588042 3367 Mitochondrial membrane organization 17 42 2.865120685916802 0.0041685034064842 Q9H3K2,O75431,Q9NS69,Q9NX63,P49840,Q9P0J0,Q9BUR5,Q9Y512,P12235,Q15070,Q16891,Q5XKP0,P45880,O60313,Q13505,O95202,O14737 Processes and pathways GO Biological process msigdb_gobp 389,97,3,461,320,230,367,565,447,360,363,502,19,279,58,123,284 2171,284,279,97,2649,123,928,553,969,2245,447,3091,1234,2432,3220,2932,19,1666,320,1467,1605,58,360,363,826,698,502,784,829,2573,2056,1090,367,389,3,878,461,230,733,734,565,1853 -0.34644068419145774,1.1254866370979533,1.1474357022138544,2.4171181472402936,-0.5982416058990344,2.19713106377011,0.22693649856222178,0.5636060512556167,0.1999552233330087,-0.37714563952921315,0.7108269558541094,-0.969620885690122,0.06254274771127205,-0.4705554931571856,-1.1493154316371736,-0.7969425638483784,3.9215673900004977,-0.1372495529245524,1.014100175743301,-0.05052375805598644,-0.10815269963874782,3.2036080031326675,0.8998745416649946,0.8998745416649946,0.30691434248850596,0.41136873678446767,0.6378225083090472,0.3332580754721944,0.30691434248850596,-0.5339391468977894,-0.28566029525923553,0.14549770029311399,0.8998745416649946,0.8533559354124849,4.832811783410612,0.2804141068248859,0.7108269558541094,1.4234149403548129,0.3854834577363446,0.3854834577363446,0.5636060512556167,-0.19602066046695343 3367 Late endosome 24 65 2.86026673031817 0.0042328482832882 Q658P3,Q9Y2Q5,Q9UNK0,P11279,Q14849,Q14108,Q8IV08,Q96PU5,O14964,Q9BRK5,Q9NZJ7,Q8IY95,Q15043,P20645,Q9H9H4,P07602,O15400,P13473,Q9ULH0,O15118,P11717,P42858,Q9BUN8,Q99538 Localization GO Cellular component msigdb_gocc 129,527,526,261,6,5,136,268,392,148,276,417,293,185,460,65,446,210,477,85,217,344,229,507 2476,392,85,446,3005,3115,1862,2370,65,1655,1176,1940,261,217,210,1942,185,2763,2431,2889,344,1019,2259,3223,1553,5,6,293,700,129,598,136,417,911,1627,703,1762,1318,2064,2525,268,1209,1096,507,1210,2789,148,229,680,1990,1921,1572,2585,460,2963,276,2293,2800,2868,477,3165,526,527,564,1163 -0.5021341373910327,0.8299141117114622,2.7359582136753127,0.7108269558541094,-0.8652075817496219,-1.004980242603473,-0.22570012371921228,-0.43919996831517205,3.0911332595741183,-0.1372495529245524,0.09036639678564706,-0.25557908848123395,1.2341735778065615,1.5050295510613063,1.5452878774447738,-0.25557908848123395,1.6639450277501382,-0.6634903102109926,-0.4705554931571856,-0.7632007073119792,0.9459148854023514,0.17280963840827135,-0.37714563952921315,-1.1493154316371736,-0.07924492702588042,4.744465578955981,4.664482621298005,1.1034296234289172,0.41136873678446767,2.16231565108635,0.5134346459158582,2.0918689378538042,0.7826588994764823,0.2537554699892711,-0.10815269963874782,0.41136873678446767,-0.16653801380920247,0.034544176031171075,-0.28566029525923553,-0.5021341373910327,1.2126457954814382,0.09036639678564706,0.14549770029311399,0.6378225083090472,0.09036639678564706,-0.6634903102109926,2.002235460610414,1.4234149403548129,0.4371047742428398,-0.25557908848123395,-0.22570012371921228,-0.07924492702588042,-0.5339391468977894,0.7108269558541094,-0.7969425638483784,1.1692778855749448,-0.37714563952921315,-0.6634903102109926,-0.7297139540963061,0.6866243286062695,-1.0406246148817728,0.6132203653820887,0.6132203653820887,0.5636060512556167,0.11801732694304702 3367 Abnormality of femur morphology 25 73 2.856601410003795 0.0042820319210936 Q14739,P06280,Q32P28,P51798,Q96A33,Q9NZJ7,Q7LGA3,Q9UHX1,O95831,P16278,Q6NUQ1,Q9NZC9,P04066,P07602,Q8WVQ1,Q96HY6,O75718,Q9Y487,P16435,O75431,Q9NUQ7,O00754,Q96L58,P04062,O75844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 266,139,140,516,274,276,152,159,35,41,424,444,184,65,457,342,206,215,222,97,493,480,378,118,127 713,735,2093,480,1276,2710,1526,2877,97,1863,206,127,2100,35,968,805,118,184,928,139,1532,65,2599,41,222,3012,1945,2431,2433,3220,1349,3124,1949,516,3289,2192,2322,2194,266,2333,1198,140,1311,424,3103,152,1824,537,2785,457,1501,274,916,871,342,378,2216,1097,2071,605,1000,1328,3082,493,1640,444,276,159,2296,1050,2233,215,2834 0.3854834577363446,0.3594471701790773,-0.31594654169938047,0.6622900003005412,0.034544176031171075,-0.6307459142786708,-0.07924492702588042,-0.7632007073119792,2.4171181472402936,-0.22570012371921228,1.5652826911718993,2.16231565108635,-0.31594654169938047,3.512290521765781,0.1999552233330087,0.30691434248850596,2.248856101291637,1.6639450277501382,0.22693649856222178,2.074084118777206,-0.07924492702588042,3.0911332595741183,-0.5659738392609449,3.367269068562799,1.4644074828289309,-0.8652075817496219,-0.25557908848123395,-0.4705554931571856,-0.4705554931571856,-1.1493154316371736,0.0063684354015670136,-1.004980242603473,-0.25557908848123395,0.6132203653820887,-1.4138401674883982,-0.34644068419145774,-0.40806438662984673,-0.34644068419145774,1.2126457954814382,-0.40806438662984673,0.09036639678564706,2.0383028111640002,0.034544176031171075,0.7588428378146155,-0.969620885690122,1.9840930614703445,-0.19602066046695343,0.588482059091134,-0.6634903102109926,0.7108269558541094,-0.05052375805598644,1.1692778855749448,0.2537554699892711,0.2804141068248859,0.9687588066338071,0.8766756507402944,-0.34644068419145774,0.14549770029311399,-0.28566029525923553,0.5134346459158582,0.1999552233330087,0.034544176031171075,-0.9345419567612725,0.6622900003005412,-0.10815269963874782,0.7348993205919421,1.1692778855749448,1.9107846516380202,-0.37714563952921315,0.17280963840827135,-0.34644068419145774,1.525203768425511,-0.6964784202356398 3367 Abnormality of the vasculature of the eye 20 75 2.8467424339659 0.0044169083136569 P38435,P21964,Q14739,P06280,Q9NZJ7,P28070,Q9NZ08,P16278,P17900,P01889,Q96DF8,P04066,P10619,P07602,P02786,Q9Y4P3,Q13510,P06865,P04439,O00462 Drugs and Diseases Human Phenotype Ontology msigdb_hp 383,396,266,139,276,36,168,41,169,302,309,184,190,65,200,205,78,81,333,126 2300,126,1053,1277,2540,2541,845,1591,1057,1455,2099,2176,302,200,184,333,3087,139,81,65,1064,3069,190,2108,2758,41,169,1286,975,2111,2430,396,2248,36,3150,2604,848,742,1661,3039,2381,383,3245,743,1541,3247,2978,1124,2258,1412,980,2266,1743,1963,3290,78,266,1426,665,862,425,723,2455,1496,1982,1501,2410,1318,309,1327,1154,168,276,958,205 -0.40806438662984673,2.1797569087503486,0.14549770029311399,0.034544176031171075,-0.5339391468977894,-0.5339391468977894,0.2804141068248859,-0.10815269963874782,0.14549770029311399,-0.05052375805598644,-0.31594654169938047,-0.34644068419145774,1.081263578277897,1.5851890116525102,1.6639450277501382,0.9687588066338071,-0.969620885690122,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,-0.9345419567612725,1.6247393272059847,-0.31594654169938047,-0.6634903102109926,3.367269068562799,1.7413465847323417,0.034544176031171075,0.1999552233330087,-0.31594654169938047,-0.4705554931571856,0.8299141117114622,-0.37714563952921315,3.473195069920084,-1.0406246148817728,-0.5659738392609449,0.2804141068248859,0.3594471701790773,-0.1372495529245524,-0.8997389788237078,-0.43919996831517205,0.8533559354124849,-1.2232904675772427,0.3594471701790773,-0.07924492702588042,-1.2232904675772427,-0.8309434988946349,0.11801732694304702,-0.37714563952921315,-0.02198676428679048,0.1999552233330087,-0.37714563952921315,-0.16653801380920247,-0.25557908848123395,-1.4138401674883982,2.8724277004854066,1.2126457954814382,-0.02198676428679048,0.4371047742428398,0.2804141068248859,0.7588428378146155,0.3854834577363446,-0.4705554931571856,-0.05052375805598644,-0.25557908848123395,-0.05052375805598644,-0.43919996831517205,0.034544176031171075,1.058987402257529,0.034544176031171075,0.11801732694304702,1.7795540517583925,1.1692778855749448,0.22693649856222178,1.5851890116525102 3367 Iron uptake and transport 6 18 2.8446720108863266 0.0044457174729877 P09601,Q658P3,P30519,P02786,Q15904,Q93050 Processes and pathways Reactome Pathways msigdb_reactome 0,129,1,200,173,92 3253,200,0,1537,2377,774,1,1539,2976,746,1411,2778,173,129,2209,92,585,215 -1.2607479309781038,1.5851890116525102,5.77073025593568,-0.07924492702588042,-0.43919996831517205,0.3332580754721944,5.215090048676801,-0.07924492702588042,-0.8309434988946349,0.3594471701790773,-0.02198676428679048,-0.6634903102109926,1.722120594018782,2.16231565108635,-0.34644068419145774,2.5793442451134623,0.5385907773537494,1.525203768425511 3367 Abnormal tongue morphology 26 79 2.842756416034048 0.0044725238001599 O43933,Q01082,P83436,Q10713,Q96A33,Q7LGA3,P48651,Q71SY5,Q8NCM8,P10253,Q96RL7,P16278,P01889,P04066,Q9UBM7,P42356,Q03252,Q9Y4P3,P98175,Q6NUK1,O60826,O75431,P20700,O00754,Q2M1P5,O75844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 132,518,517,398,274,152,533,33,537,163,297,41,302,184,325,571,328,205,451,599,593,97,359,480,253,127 1854,735,2707,480,962,1114,2751,3065,2540,132,593,1789,97,1395,127,2023,302,805,184,1064,2105,163,2599,41,359,1537,3012,2430,2431,1661,1799,571,1349,3124,533,1238,781,1739,1412,517,451,518,1960,328,1417,398,2776,1194,903,1817,1426,1307,253,2136,1137,599,33,152,537,1910,274,1318,297,628,1097,2220,955,1993,956,2464,1515,325,2227,958,205,2090,2967,712,1274 -0.22570012371921228,0.3594471701790773,-0.6307459142786708,0.6622900003005412,0.1999552233330087,0.11801732694304702,-0.6634903102109926,-0.9345419567612725,-0.5339391468977894,2.12722970929693,0.5134346459158582,-0.19602066046695343,2.4171181472402936,-0.02198676428679048,2.16231565108635,-0.28566029525923553,1.081263578277897,0.30691434248850596,1.6639450277501382,0.14549770029311399,-0.31594654169938047,1.8362643641609107,-0.5659738392609449,3.367269068562799,0.8998745416649946,-0.07924492702588042,-0.8652075817496219,-0.4705554931571856,-0.4705554931571856,-0.1372495529245524,-0.19602066046695343,0.5385907773537494,0.0063684354015670136,-1.004980242603473,0.588482059091134,0.06254274771127205,0.3332580754721944,-0.16653801380920247,-0.02198676428679048,0.6132203653820887,0.7108269558541094,0.6132203653820887,-0.25557908848123395,0.9914868411153721,-0.02198676428679048,0.8299141117114622,-0.6634903102109926,0.09036639678564706,0.2537554699892711,-0.19602066046695343,-0.02198676428679048,0.034544176031171075,1.276921824455599,-0.31594654169938047,0.11801732694304702,0.5134346459158582,3.525248122809391,1.9840930614703445,0.588482059091134,-0.22570012371921228,1.1692778855749448,0.034544176031171075,1.1034296234289172,0.488136037900703,0.14549770029311399,-0.34644068419145774,0.22693649856222178,-0.25557908848123395,0.22693649856222178,-0.4705554931571856,-0.05052375805598644,1.014100175743301,-0.34644068419145774,0.22693649856222178,1.5851890116525102,-0.28566029525923553,-0.7969425638483784,0.41136873678446767,0.06254274771127205 3367 Golgi apparatus 56 173 2.8369189188866875 0.0045551178054432 P09601,Q6ZRP7,P24390,Q01082,Q92896,P50570,P80303,Q5VW38,Q9BRK5,Q9NPR9,Q8TD16,P50897,Q08379,Q9UQ16,O60637,Q6NT16,Q99996,Q9HB40,O75955,Q8IYS2,Q16706,Q15043,P16278,Q5KU26,Q6NUQ1,Q02818,P49755,Q6ZU35,Q8NC54,Q8IXU6,O00461,O95070,A1L0T0,Q86SF2,Q9BSL1,O43752,Q8WVQ1,O75071,O15258,P04439,O43760,P11717,P05067,O00231,Q93050,P67812,Q13190,Q8IZA0,O60476,Q86VS8,O15127,Q9HD45,Q9NTJ5,O15260,Q9Y678,P35606 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 0,258,2,518,137,264,15,16,148,20,404,26,287,282,31,32,160,34,162,296,294,293,41,171,424,46,437,440,51,52,53,179,313,317,459,189,457,68,445,333,216,217,90,463,92,93,355,100,235,364,239,112,509,121,391,497 313,1111,2361,2171,463,53,3347,1935,801,239,445,121,633,1343,2922,1859,1651,3167,1453,189,216,235,2302,31,691,3007,68,2366,2877,2925,162,179,891,968,333,90,2651,0,3213,217,555,41,1536,2314,2,2602,2813,3175,1661,497,2251,2319,2552,2117,1949,437,264,1124,26,2661,1069,979,2437,2723,1670,1544,3157,93,15,517,518,46,2396,2941,287,664,1743,355,2944,1745,782,2447,293,294,666,2903,171,2448,2134,16,3160,1431,598,2732,32,1313,424,600,1751,1622,258,3103,440,1978,317,2209,364,828,2407,943,1314,52,1905,296,100,1315,626,2516,51,2408,404,2283,457,1257,137,1038,92,1143,1830,2213,3310,2216,2067,1096,2459,160,3208,148,459,1510,1990,2074,2910,917,2150,1214,1216,3209,2151,1003,34,1709,112,20,2465,1515,509,1268,882,1048,769,2294,2998,2749,2642,632,282,2231,1849,3063,2014,391,1934 1.0365999791862452,0.11801732694304702,-0.43919996831517205,-0.34644068419145774,0.6866243286062695,3.245078698171657,-1.8215870556151397,-0.25557908848123395,0.30691434248850596,1.3612162919778177,0.7108269558541094,2.214438638015626,0.46269330605308917,0.0063684354015670136,-0.7969425638483784,-0.22570012371921228,-0.1372495529245524,-1.0765587039609845,-0.05052375805598644,1.6247393272059847,1.5050295510613063,1.3820450016487578,-0.40806438662984673,3.5639012562238195,0.41136873678446767,-0.8652075817496219,2.975802844788199,-0.43919996831517205,-0.7632007073119792,-0.7969425638483784,1.8550102756937976,1.7028121530513547,0.2537554699892711,0.1999552233330087,0.9687588066338071,2.595251590463738,-0.5982416058990344,5.77073025593568,-1.1493154316371736,1.5050295510613063,0.5636060512556167,3.367269068562799,-0.07924492702588042,-0.40806438662984673,5.106453588871854,-0.5659738392609449,-0.6964784202356398,-1.0765587039609845,-0.1372495529245524,0.6378225083090472,-0.37714563952921315,-0.40806438662984673,-0.5339391468977894,-0.31594654169938047,-0.25557908848123395,0.7348993205919421,1.2126457954814382,0.11801732694304702,3.6904275097045454,-0.5982416058990344,0.14549770029311399,0.1999552233330087,-0.4705554931571856,-0.6307459142786708,-0.1372495529245524,-0.07924492702588042,-1.0406246148817728,2.5151499572076714,4.164124775027304,0.6132203653820887,0.6132203653820887,3.286174597616811,-0.43919996831517205,-0.7969425638483784,1.1254866370979533,0.4371047742428398,-0.16653801380920247,0.9229538719151944,-0.7969425638483784,-0.16653801380920247,0.3332580754721944,-0.4705554931571856,1.1034296234289172,1.1034296234289172,0.4371047742428398,-0.7632007073119792,1.7413465847323417,-0.4705554931571856,-0.31594654169938047,4.130251742479455,-1.0406246148817728,-0.02198676428679048,0.5134346459158582,-0.6307459142786708,3.5639012562238195,0.034544176031171075,0.7588428378146155,0.5134346459158582,-0.16653801380920247,-0.10815269963874782,1.2555985905367433,-0.969620885690122,0.7348993205919421,-0.25557908848123395,1.0365999791862452,-0.34644068419145774,0.8998745416649946,0.30691434248850596,-0.43919996831517205,0.22693649856222178,0.034544176031171075,3.258818635054596,-0.22570012371921228,1.1034296234289172,2.4171181472402936,0.034544176031171075,0.488136037900703,-0.5021341373910327,3.272517184127066,-0.43919996831517205,0.8063488749900722,-0.37714563952921315,0.7108269558541094,0.06254274771127205,2.0918689378538042,0.17280963840827135,2.5793442451134623,0.11801732694304702,-0.19602066046695343,-0.34644068419145774,-1.4924261166507573,-0.34644068419145774,-0.28566029525923553,0.14549770029311399,-0.4705554931571856,1.8736785287250628,-1.112787329154505,2.002235460610414,0.7108269558541094,-0.05052375805598644,-0.25557908848123395,-0.28566029525923553,-0.7632007073119792,0.2537554699892711,-0.31594654169938047,0.09036639678564706,0.09036639678564706,-1.112787329154505,-0.31594654169938047,0.1999552233330087,3.525248122809391,-0.1372495529245524,2.2999956417932186,3.897780748473081,-0.4705554931571856,-0.05052375805598644,0.6378225083090472,0.06254274771127205,0.2804141068248859,0.17280963840827135,0.3594471701790773,-0.37714563952921315,-0.8309434988946349,-0.6307459142786708,-0.5659738392609449,0.488136037900703,1.1474357022138544,-0.34644068419145774,-0.19602066046695343,-0.8997389788237078,-0.25557908848123395,0.8533559354124849,-0.22570012371921228 3367 Glycosaminoglycan metabolism 6 12 2.831193538626762 0.0046374650622742 P15586,P16278,Q8TB61,P06865,P54802,Q7LGA3 Processes and pathways Reactome Pathways msigdb_reactome 128,41,44,81,83,152 2240,195,529,81,1064,128,41,83,152,44,378,2162 -0.37714563952921315,1.605007630123358,0.588482059091134,2.781905953857426,0.14549770029311399,2.16231565108635,3.367269068562799,2.7513259355917703,1.9840930614703445,3.34039786005235,0.8766756507402944,-0.31594654169938047 3367 Biliary tract abnormality 12 29 2.823138777611481 0.0047555981598395 P09601,P07602,O43933,Q14108,Q14739,Q10713,O96028,Q9NZJ7,Q9NSD9,P04062,Q5XKP0,O95202 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,65,132,5,266,398,401,276,474,118,502,123 738,132,123,401,805,118,65,0,893,555,3302,849,1666,1292,398,696,2566,5,266,502,1501,1983,726,1327,474,276,1930,733,2474 0.3594471701790773,2.12722970929693,2.19713106377011,0.8063488749900722,0.30691434248850596,2.248856101291637,3.0911332595741183,5.77073025593568,0.2537554699892711,0.5636060512556167,-1.4924261166507573,0.2804141068248859,-0.1372495529245524,0.034544176031171075,0.8299141117114622,0.41136873678446767,-0.5339391468977894,4.744465578955981,1.2126457954814382,0.6378225083090472,-0.05052375805598644,-0.25557908848123395,0.3854834577363446,0.034544176031171075,0.6866243286062695,1.1692778855749448,-0.22570012371921228,0.3854834577363446,-0.4705554931571856 3367 Establishment of protein localization to membrane 21 82 2.815433418736188 0.0048711489423154 O00560,Q9NS69,Q15629,P43307,Q96A33,O60725,P46379,O14737,Q15904,Q99442,Q9H9H4,P56589,O15118,Q15041,Q4J6C6,Q9UPN3,Q9P0J0,Q15070,Q9HD20,P27105,P31751 Processes and pathways GO Biological process msigdb_gobp 495,3,10,17,274,144,29,284,173,176,460,449,85,223,347,494,230,360,115,124,257 1275,2171,495,284,801,85,738,1055,144,3294,2547,2649,1171,969,2177,1944,124,1234,3219,257,2432,2931,1288,17,29,2552,897,1019,1022,449,3286,3222,2324,2194,933,852,2938,518,1815,1078,1965,1425,223,1817,360,10,173,347,576,698,1135,719,2737,943,1627,912,1694,1090,274,1209,176,2528,1327,955,1214,1216,460,115,1709,3,1926,230,766,1106,2162,2294,2998,494,733,2088,565,1853 0.034544176031171075,-0.34644068419145774,0.6378225083090472,1.1254866370979533,0.30691434248850596,2.7359582136753127,0.3594471701790773,0.14549770029311399,2.002235460610414,-1.45295805178107,-0.5339391468977894,-0.5982416058990344,0.09036639678564706,0.1999552233330087,-0.34644068419145774,-0.25557908848123395,2.19713106377011,0.06254274771127205,-1.1493154316371736,1.2555985905367433,-0.4705554931571856,-0.7969425638483784,0.034544176031171075,4.027100565880452,3.614933961940769,-0.5339391468977894,0.2537554699892711,0.17280963840827135,0.17280963840827135,0.7108269558541094,-1.37506621536203,-1.1493154316371736,-0.40806438662984673,-0.34644068419145774,0.22693649856222178,0.2804141068248859,-0.7969425638483784,0.6132203653820887,-0.19602066046695343,0.14549770029311399,-0.25557908848123395,-0.02198676428679048,1.4644074828289309,-0.19602066046695343,0.8998745416649946,4.2752571823438945,1.722120594018782,0.9459148854023514,0.5385907773537494,0.41136873678446767,0.11801732694304702,0.3854834577363446,-0.6307459142786708,0.22693649856222178,-0.10815269963874782,0.2537554699892711,-0.1372495529245524,0.14549770029311399,1.1692778855749448,0.09036639678564706,1.722120594018782,-0.5021341373910327,0.034544176031171075,0.22693649856222178,0.09036639678564706,0.09036639678564706,0.7108269558541094,2.283013353361886,-0.1372495529245524,4.832811783410612,-0.22570012371921228,1.4234149403548129,0.3594471701790773,0.14549770029311399,-0.31594654169938047,-0.37714563952921315,-0.8309434988946349,0.6622900003005412,0.3854834577363446,-0.28566029525923553,0.5636060512556167,-0.19602066046695343 3367 Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 7 17 2.813294633805134 0.0049036697684348 Q07065,O43852,Q02818,Q86UP2,Q9BTY2,P05067,P19022 Processes and pathways Reactome Pathways msigdb_reactome 131,196,46,305,249,90,286 196,393,90,1345,2106,972,1118,286,46,131,695,558,2615,1361,1428,305,249 1.605007630123358,0.8299141117114622,2.595251590463738,0.0063684354015670136,-0.31594654169938047,0.1999552233330087,0.11801732694304702,1.1254866370979533,3.286174597616811,2.144806762718082,0.41136873678446767,0.5636060512556167,-0.5659738392609449,0.0063684354015670136,-0.02198676428679048,1.081263578277897,1.2981442560194676 3367 Vacuole organization 13 54 2.813237421419648 0.0049045423895519 P10253,Q12768,Q14108,O14773,Q16706,O75503,P11117,P16615,Q8N511,Q96GC9,P54802,P04062,P50897 Processes and pathways GO Biological process msigdb_gobp 163,321,5,70,294,102,108,290,48,310,83,118,26 2171,70,2367,102,891,2970,2369,118,2370,1064,163,108,290,773,498,1124,26,1019,979,83,2845,2259,2560,321,5,1817,1360,294,598,364,828,48,1911,1696,1318,310,2526,1209,2528,1000,1572,955,2796,1926,2963,2293,1335,2296,3165,651,1850,3299,2966,2089 -0.34644068419145774,2.9465065973455364,-0.43919996831517205,2.40057096317167,0.2537554699892711,-0.8309434988946349,-0.43919996831517205,2.248856101291637,-0.43919996831517205,0.14549770029311399,1.8362643641609107,2.333769977004763,1.1034296234289172,0.3332580754721944,0.6378225083090472,0.11801732694304702,3.6904275097045454,0.17280963840827135,0.1999552233330087,2.7513259355917703,-0.7297139540963061,-0.37714563952921315,-0.5339391468977894,1.014100175743301,4.744465578955981,-0.19602066046695343,0.0063684354015670136,1.1034296234289172,0.5134346459158582,0.8998745416649946,0.30691434248850596,3.286174597616811,-0.22570012371921228,-0.1372495529245524,0.034544176031171075,1.058987402257529,-0.5021341373910327,0.09036639678564706,-0.5021341373910327,0.1999552233330087,-0.07924492702588042,0.22693649856222178,-0.6634903102109926,-0.22570012371921228,-0.7969425638483784,-0.37714563952921315,0.034544176031171075,-0.37714563952921315,-1.0406246148817728,0.46269330605308917,-0.19602066046695343,-1.45295805178107,-0.7969425638483784,-0.28566029525923553 3367 Clumsiness 7 22 2.77157480624088 0.0055785852581335 P07602,O14773,O75503,Q15067,Q13510,Q9NZJ7,Q9NR77 Drugs and Diseases Human Phenotype Ontology msigdb_hp 65,70,102,232,78,276,214 480,70,1276,738,654,102,1063,65,555,2604,2930,344,1417,1553,78,232,1431,1253,1094,214,276,1519 0.6622900003005412,2.9465065973455364,0.034544176031171075,0.3594471701790773,0.4371047742428398,2.40057096317167,0.14549770029311399,3.0911332595741183,0.5636060512556167,-0.5659738392609449,-0.7969425638483784,0.9459148854023514,-0.02198676428679048,-0.07924492702588042,2.8724277004854066,1.402777585756001,-0.02198676428679048,0.06254274771127205,0.14549770029311399,1.525203768425511,1.1692778855749448,-0.05052375805598644 3367 Cell surface 19 74 2.770124100913524 0.0056034938060784 P11279,O96005,P19022,O75955,P42892,P01889,P55899,O15031,P41440,Q8WTV0,P09104,P02786,Q8TCT9,P04439,P11717,P05067,Q13641,P08183,P25705 Localization GO Cellular component msigdb_gocc 261,150,286,162,43,302,180,314,186,60,327,200,202,333,217,90,346,110,244 314,445,550,529,2098,162,150,2307,302,200,2484,333,90,1531,435,3235,1345,2370,110,807,1065,327,1656,2653,481,3034,971,261,217,1941,893,2109,1346,772,286,244,611,2764,2113,2885,639,2031,186,43,2383,743,2935,2608,180,1353,1549,695,345,2612,1131,1815,2042,1242,346,3201,858,1478,2206,1032,202,60,2142,1507,1509,1043,2079,1581,1932,2536 1.0365999791862452,0.7108269558541094,0.5636060512556167,0.588482059091134,-0.31594654169938047,1.8550102756937976,1.9840930614703445,-0.40806438662984673,1.081263578277897,1.5851890116525102,-0.5021341373910327,0.9687588066338071,2.595251590463738,-0.07924492702588042,0.7348993205919421,-1.1861480785988963,0.0063684354015670136,-0.43919996831517205,2.2999956417932186,0.30691434248850596,0.14549770029311399,0.9914868411153721,-0.1372495529245524,-0.5982416058990344,0.6622900003005412,-0.8997389788237078,0.1999552233330087,1.2341735778065615,1.5050295510613063,-0.25557908848123395,0.2537554699892711,-0.31594654169938047,0.0063684354015670136,0.3332580754721944,1.1254866370979533,1.3192668476331657,0.488136037900703,-0.6634903102109926,-0.31594654169938047,-0.7632007073119792,0.46269330605308917,-0.28566029525923553,1.6639450277501382,3.34039786005235,-0.43919996831517205,0.3594471701790773,-0.7969425638483784,-0.5659738392609449,1.7028121530513547,0.0063684354015670136,-0.07924492702588042,0.41136873678446767,0.9459148854023514,-0.5659738392609449,0.11801732694304702,-0.19602066046695343,-0.28566029525923553,0.06254274771127205,0.9459148854023514,-1.112787329154505,0.2804141068248859,-0.05052375805598644,-0.34644068419145774,0.17280963840827135,1.5851890116525102,3.1896999455248927,-0.31594654169938047,-0.05052375805598644,-0.05052375805598644,0.17280963840827135,-0.28566029525923553,-0.07924492702588042,-0.22570012371921228,-0.5021341373910327 3367 Sphingolipid metabolism 6 11 2.7697403593598717 0.0056100993923589 O15269,P16278,P06280,Q06136,Q13510,P04062 Processes and pathways KEGG Pathways msigdb_kegg 220,41,139,77,78,118 220,965,738,250,118,139,555,41,77,78,796 1.4644074828289309,0.1999552233330087,0.3594471701790773,1.276921824455599,2.248856101291637,2.074084118777206,0.5636060512556167,3.367269068562799,2.8724277004854066,2.8724277004854066,0.3332580754721944 3367 Cellular hormone metabolic process 7 17 2.767692138169608 0.0056454756873507 P30536,Q53GQ0,Q9HB40,Q14849,P42892,Q8NBQ5,O95470 Processes and pathways GO Biological process msigdb_gobp 191,295,34,6,43,403,250 1788,250,2928,191,43,1292,1545,6,1308,295,415,536,403,1628,3026,34,1585 -0.19602066046695343,1.276921824455599,-0.7969425638483784,1.6247393272059847,3.34039786005235,0.034544176031171075,-0.07924492702588042,4.664482621298005,0.034544176031171075,1.1034296234289172,0.7826588994764823,0.588482059091134,0.8063488749900722,-0.10815269963874782,-0.8652075817496219,3.525248122809391,-0.07924492702588042 3367 Sphingolipid biosynthetic process 9 16 2.76684587990216 0.0056601506754612 O15269,Q96G23,Q06136,Q13510,Q99805,P04062,O95470,P27544,Q9P035 Processes and pathways GO Biological process msigdb_gobp 220,66,77,78,379,118,250,467,260 220,965,250,118,2314,467,2396,77,519,78,698,66,379,796,260,1155 1.4644074828289309,0.1999552233330087,1.276921824455599,2.248856101291637,-0.40806438662984673,0.6866243286062695,-0.43919996831517205,2.8724277004854066,0.6132203653820887,2.8724277004854066,0.41136873678446767,3.0911332595741183,0.8766756507402944,0.3332580754721944,1.2555985905367433,0.11801732694304702 3367 Organelle membrane contact site 9 14 2.7613060464046004 0.0057570699972189 Q96N66,Q14849,Q96TC7,P27824,P51572,Q9NTJ5,Q5XKP0,O96008,Q9Y320 Localization GO Cellular component msigdb_gocc 101,6,343,556,273,509,502,466,420 589,2302,466,556,273,6,502,868,1206,101,343,1210,509,420 0.5134346459158582,-0.40806438662984673,0.6866243286062695,0.5636060512556167,1.1692778855749448,4.664482621298005,0.6378225083090472,0.2804141068248859,0.09036639678564706,2.4171181472402936,0.9687588066338071,0.09036639678564706,0.6378225083090472,0.7826588994764823 3367 Trans golgi network vesicle budding 12 34 2.760175092567448 0.0057770390040585 P15586,Q12846,P11717,P50570,P02786,Q9Y5X3,O14964,O75976,P20645,P05067,O60749,Q9Y5X1 Processes and pathways Reactome Pathways msigdb_reactome 128,345,217,264,200,567,392,183,185,90,465,30 2171,735,392,1935,1653,465,183,891,200,90,554,1594,1940,217,128,185,264,977,1804,1544,817,1677,1743,345,2042,2202,782,2783,1257,1980,1837,917,30,567 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P24390,Q9NS69,O43676,Q9UNK0,Q14849,Q9BRG1,Q9BQE5,O60830,Q15629,Q99595,O43615,P21796,P83436,P51798,O75352,Q9BVK6,Q9UBX3,P45880,Q9Y277,Q70HW3,Q99720,P46379,Q9Y5X1,Q6NT16,Q9UDW1,Q8TB61,O75964,Q8IXU6,Q9P2W9,O00461,A6NIH7,Q13505,Q9H2D1,Q9BTX1,Q9C0H2,Q9Y3B3,O43169,O15118,P30825,Q93050,O75431,P53985,Q9Y282,O95197,P08183,Q9HD20,O95202,Q658P3,Q6DKK2,O43933,O43772,Q9H1E5,P00403,O60831,Q15904,Q99442,O95070,P20645,P41440,O43752,P61916,Q96D46,Q9BSK2,Q8TAG9,Q9Y487,P11717,Q2M389,Q9BUN8,Q9P0J0,Q8N1F7,O15127,P25705,O15397,O95721,P31751,Q99808,P51572,Q9NZJ7,Q08379,Q9Y3E0,Q96RL7,Q15043,P16615,Q9Y6C9,Q9H2U1,P12236,Q9HC21,Q12768,O75381,A0AVF1,Q86Y39,Q9Y3Y2,Q8NE01,Q12846,Q13190,Q9BUR5,Q86VS8,O00410,P28288,Q9Y678,Q9H0U3,Q9BVC6,O75746,Q6P4Q7,O14964,Q8TD16,Q92973,Q9C0E2,P24539,O43707,Q9UPT5,Q6NUQ1,P49755,P20020,P06576,Q9H9H4,P12235,Q9H3N1,Q9P260,Q14203,Q8TEX9,O96008,O60749,O14925,Q9BZF1,P50416,P47985,P22695,Q15833,Q12981,P35606 Processes and pathways Protein Atlas Biological process 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3367 Lipid transporter activity 9 20 2.721097864354149 0.0065065495900802 P30536,Q9BZF1,P61916,Q14849,P17900,P08183,Q96GC9,O15118,P28288 Functions GO Molecular function msigdb_gomf 191,491,197,6,169,110,310,85,372 1390,85,110,692,169,2314,372,191,2435,197,1547,6,1822,310,1096,1990,491,761,582,1009 -0.02198676428679048,2.7359582136753127,2.2999956417932186,0.41136873678446767,1.7413465847323417,-0.40806438662984673,0.8766756507402944,1.6247393272059847,-0.4705554931571856,1.605007630123358,-0.07924492702588042,4.664482621298005,-0.19602066046695343,1.058987402257529,0.14549770029311399,-0.25557908848123395,0.6622900003005412,0.3594471701790773,0.5385907773537494,0.1999552233330087 3367 Active ion transmembrane transporter activity 16 32 2.7168311116882644 0.0065910230896077 P13073,Q15043,Q9UDW1,P12235,P16615,P51798,P47985,P00403,P05141,Q9HD20,P20020,P06576,P12236,P41440,O95202,Q9UI12 Functions GO Molecular function msigdb_gomf 167,293,40,447,290,516,484,145,553,115,436,435,307,186,123,585 123,145,610,553,435,807,970,1872,447,307,167,290,436,1797,1537,2377,3038,1539,2976,186,484,516,1071,2322,746,1548,980,293,2636,115,40,585 2.19713106377011,2.002235460610414,0.488136037900703,0.5636060512556167,0.7348993205919421,0.30691434248850596,0.1999552233330087,-0.22570012371921228,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,-0.8997389788237078,-0.07924492702588042,-0.8309434988946349,1.6639450277501382,0.6622900003005412,0.6132203653820887,0.14549770029311399,-0.40806438662984673,0.3594471701790773,-0.07924492702588042,0.1999552233330087,1.1034296234289172,-0.5659738392609449,2.283013353361886,3.380645404831543,0.5385907773537494 3367 CD markers 6 15 2.7132577310478068 0.0066625265837088 P11279,P35613,P02786,P08183,P13473,P11717 Functions Protein Atlas Protein class protein_atlas_protein_class 261,165,200,110,210,217 1648,529,200,1531,110,807,261,217,210,286,165,2383,1126,1476,2705 -0.1372495529245524,0.588482059091134,1.5851890116525102,-0.07924492702588042,2.2999956417932186,0.30691434248850596,1.2341735778065615,1.5050295510613063,1.5452878774447738,1.1254866370979533,1.7985369233817154,-0.43919996831517205,0.11801732694304702,-0.05052375805598644,-0.5982416058990344 3367 Neuron death 12 74 2.711157596486349 0.00670487501201 P09601,O95831,Q92542,P05067,Q9UMX5,Q15392,Q96A26,Q01105,Q9NR28,P04062,P50897,Q99720 Processes and pathways GO Biological process msigdb_gobp 0,35,227,90,73,76,175,181,213,118,26,28 2646,3064,1648,1279,609,1168,393,804,35,118,3255,2713,928,90,1174,1532,1795,1065,327,0,2374,1534,1346,2601,257,742,2434,2891,659,2934,1666,1465,2256,743,2555,1467,26,2037,2556,1606,2770,2725,2039,1956,2938,3306,181,1416,1191,2613,1551,615,2042,718,76,1752,227,1092,175,3134,2143,1209,3280,507,28,762,920,213,2162,1783,73,960,1386,1164 -0.5982416058990344,-0.9345419567612725,-0.1372495529245524,0.034544176031171075,0.488136037900703,0.09036639678564706,0.8299141117114622,0.30691434248850596,3.512290521765781,2.248856101291637,-1.2607479309781038,-0.6307459142786708,0.22693649856222178,2.595251590463738,0.09036639678564706,-0.07924492702588042,-0.19602066046695343,0.14549770029311399,0.9914868411153721,5.77073025593568,-0.43919996831517205,-0.07924492702588042,0.0063684354015670136,-0.5659738392609449,1.2555985905367433,0.3594471701790773,-0.4705554931571856,-0.7632007073119792,0.4371047742428398,-0.7969425638483784,-0.1372495529245524,-0.05052375805598644,-0.37714563952921315,0.3594471701790773,-0.5339391468977894,-0.05052375805598644,3.6904275097045454,-0.28566029525923553,-0.5339391468977894,-0.10815269963874782,-0.6634903102109926,-0.6307459142786708,-0.28566029525923553,-0.25557908848123395,-0.7969425638483784,-1.4924261166507573,1.7028121530513547,-0.02198676428679048,0.09036639678564706,-0.5659738392609449,-0.07924492702588042,0.488136037900703,-0.28566029525923553,0.3854834577363446,2.8873405559171093,-0.16653801380920247,1.443957948969997,0.14549770029311399,1.722120594018782,-1.004980242603473,-0.31594654169938047,0.09036639678564706,-1.3366301135330916,0.6378225083090472,3.665401627508389,0.3594471701790773,0.2537554699892711,1.525203768425511,-0.31594654169938047,-0.16653801380920247,2.9465065973455364,0.22693649856222178,0.0063684354015670136,0.11801732694304702 3367 Toe walking 11 25 2.7090590395326237 0.0067474331667121 P07602,O95831,Q01082,Q8WXH0,Q13057,P15289,Q8TD16,Q9NZJ7,Q99720,P35637,P50402 Drugs and Diseases Human Phenotype Ontology msigdb_hp 65,35,518,331,500,555,404,276,28,192,193 738,35,805,1063,65,555,192,2116,193,1071,1470,2818,2895,518,500,1554,1755,1087,404,331,2412,28,581,276,1274 0.3594471701790773,3.512290521765781,0.30691434248850596,0.14549770029311399,3.0911332595741183,0.5636060512556167,1.6247393272059847,-0.31594654169938047,1.6247393272059847,0.14549770029311399,-0.05052375805598644,-0.6964784202356398,-0.7632007073119792,0.6132203653820887,0.6378225083090472,-0.07924492702588042,-0.16653801380920247,0.14549770029311399,0.8063488749900722,0.9914868411153721,-0.43919996831517205,3.665401627508389,0.5385907773537494,1.1692778855749448,0.06254274771127205 3367 Lipid metabolism 36 127 2.7033281594404457 0.0068648933949797 Q14739,Q99735,O15254,Q14914,O00767,Q53GQ0,Q15125,P17900,Q8NHP8,Q9H6V9,Q9NPH0,P35610,A1L0T0,Q8NCC3,Q8N2A8,Q96G23,P07602,Q9H7Z7,Q15800,P61916,P35790,Q15392,Q06136,Q13510,P34913,O15118,P51648,Q16850,O15269,P48449,Q96N66,Q15067,Q92604,P04062,O95470,Q9P035 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 266,147,149,25,283,295,166,169,49,50,177,308,313,63,194,66,65,67,69,197,201,76,77,78,207,85,88,94,220,98,101,232,245,118,250,260 313,713,2537,3318,283,2708,1113,1390,85,149,220,965,2302,3294,2023,250,1171,395,2102,892,2808,118,3341,65,3033,655,3362,3335,1284,169,1181,3089,1347,2882,3149,467,2186,3218,1798,207,308,201,483,2433,3354,2116,2493,2932,1879,2933,98,533,743,1466,485,1019,88,1292,1886,2892,898,2895,1545,197,2495,2441,1472,3358,2266,77,2672,3352,519,78,1421,2043,3021,266,25,232,1748,166,3225,2203,76,1247,69,2204,94,619,1248,295,1822,622,830,194,419,403,63,1367,49,2519,539,245,1831,66,101,3260,3109,3026,147,580,2794,917,50,67,177,1776,685,260,325,882,711,2470,2747,1160,1274 1.0365999791862452,0.3854834577363446,-0.5339391468977894,-1.5724386516725661,1.1254866370979533,-0.6307459142786708,0.11801732694304702,-0.02198676428679048,2.7359582136753127,1.9840930614703445,1.4644074828289309,0.1999552233330087,-0.40806438662984673,-1.45295805178107,-0.28566029525923553,1.276921824455599,0.09036639678564706,0.8299141117114622,-0.31594654169938047,0.2537554699892711,-0.6964784202356398,2.248856101291637,-1.736960805865547,3.0911332595741183,-0.8997389788237078,0.4371047742428398,-3.2895262347862597,-1.6539313317624937,0.034544176031171075,1.7413465847323417,0.09036639678564706,-0.969620885690122,0.0063684354015670136,-0.7632007073119792,-1.0406246148817728,0.6866243286062695,-0.34644068419145774,-1.1493154316371736,-0.19602066046695343,1.5652826911718993,1.058987402257529,1.5851890116525102,0.6622900003005412,-0.4705554931571856,-1.951622338591048,-0.31594654169938047,-0.5021341373910327,-0.7969425638483784,-0.22570012371921228,-0.7969425638483784,2.4171181472402936,0.588482059091134,0.3594471701790773,-0.05052375805598644,0.6622900003005412,0.17280963840827135,2.6739608306410108,0.034544176031171075,-0.22570012371921228,-0.7632007073119792,0.2537554699892711,-0.7632007073119792,-0.07924492702588042,1.605007630123358,-0.5021341373910327,-0.4705554931571856,-0.05052375805598644,-2.176639462165624,-0.37714563952921315,2.8724277004854066,-0.5982416058990344,-1.907862431915821,0.6132203653820887,2.8724277004854066,-0.02198676428679048,-0.28566029525923553,-0.8652075817496219,1.2126457954814382,3.7400710224882556,1.402777585756001,-0.16653801380920247,1.7985369233817154,-1.1493154316371736,-0.34644068419145774,2.8873405559171093,0.06254274771127205,2.9611783576004687,-0.34644068419145774,2.482708122078919,0.488136037900703,0.06254274771127205,1.1034296234289172,-0.19602066046695343,0.488136037900703,0.30691434248850596,1.6247393272059847,0.7826588994764823,0.8063488749900722,3.1336381893089387,0.0063684354015670136,3.286174597616811,-0.5021341373910327,0.588482059091134,1.3192668476331657,-0.19602066046695343,3.0911332595741183,2.4171181472402936,-1.2607479309781038,-0.969620885690122,-0.8652075817496219,2.002235460610414,0.5385907773537494,-0.6634903102109926,0.2537554699892711,3.286174597616811,3.062574077848557,1.722120594018782,-0.16653801380920247,0.4371047742428398,1.2555985905367433,1.014100175743301,0.2804141068248859,0.41136873678446767,-0.4705554931571856,-0.6307459142786708,0.11801732694304702,0.06254274771127205 3367 Increased bone mineral density 9 29 2.7015757533731266 0.0069011757372385 Q14108,Q15125,Q14191,Q14739,Q15392,Q9Y4P3,P54802,P04062,Q13126 Drugs and Diseases Human Phenotype Ontology msigdb_hp 5,166,265,266,76,205,83,118,95 3030,2540,805,118,1286,975,3012,2248,1661,533,516,83,2818,1412,3223,95,1553,5,265,266,293,1426,166,76,2850,871,958,2591,205 -0.8997389788237078,-0.5339391468977894,0.30691434248850596,2.248856101291637,0.034544176031171075,0.1999552233330087,-0.8652075817496219,-0.37714563952921315,-0.1372495529245524,0.588482059091134,0.6132203653820887,2.7513259355917703,-0.6964784202356398,-0.02198676428679048,-1.1493154316371736,2.4663995632740083,-0.07924492702588042,4.744465578955981,1.2126457954814382,1.2126457954814382,1.1034296234289172,-0.02198676428679048,1.7985369233817154,2.8873405559171093,-0.7297139540963061,0.2804141068248859,0.22693649856222178,-0.5339391468977894,1.5851890116525102 3367 Protein insertion into membrane 6 23 2.7010627999737795 0.0069118286228053 Q9NS69,Q9P0J0,Q15629,Q96A33,P46379,O14737 Processes and pathways GO Biological process msigdb_gobp 3,230,10,274,29,284 284,738,1055,2649,969,1234,2432,29,852,1425,360,10,698,1135,719,912,1090,274,3,230,733,565,1853 1.1254866370979533,0.3594471701790773,0.14549770029311399,-0.5982416058990344,0.1999552233330087,0.06254274771127205,-0.4705554931571856,3.614933961940769,0.2804141068248859,-0.02198676428679048,0.8998745416649946,4.2752571823438945,0.41136873678446767,0.11801732694304702,0.3854834577363446,0.2537554699892711,0.14549770029311399,1.1692778855749448,4.832811783410612,1.4234149403548129,0.3854834577363446,0.5636060512556167,-0.19602066046695343 3367 Transport vesicle 26 82 2.699776624694682 0.0069386045692314 P24390,P11279,O76024,Q9BVK6,P50897,O00429,P01889,P49755,P09496,O00461,P20020,P20645,O43752,O15400,Q9Y3B3,P04439,O43760,P11717,P05067,Q12846,Q92542,Q13190,P10321,O15260,Q9Y678,P35606 Localization GO Cellular component msigdb_gocc 2,261,393,541,26,300,302,437,554,53,436,185,189,446,75,333,216,217,90,345,227,355,481,121,391,497 300,53,3347,801,121,446,1524,1653,189,216,845,1394,691,2544,2367,2098,393,1230,891,1170,1282,1062,302,333,90,554,1594,481,261,217,436,773,185,2,3070,2113,497,2976,1949,572,437,26,1019,3152,2723,1670,2258,2896,2324,933,2259,746,1737,2560,817,345,355,2042,2043,938,2331,1026,1360,3277,1556,1307,828,227,1980,724,839,541,1709,795,2639,2468,2469,2162,3144,75,391,1586 1.081263578277897,3.245078698171657,-1.8215870556151397,0.30691434248850596,2.214438638015626,0.7108269558541094,-0.07924492702588042,-0.1372495529245524,1.6247393272059847,1.5050295510613063,0.2804141068248859,-0.02198676428679048,0.41136873678446767,-0.5339391468977894,-0.43919996831517205,-0.31594654169938047,0.8299141117114622,0.06254274771127205,0.2537554699892711,0.09036639678564706,0.034544176031171075,0.14549770029311399,1.081263578277897,0.9687588066338071,2.595251590463738,0.5636060512556167,-0.10815269963874782,0.6622900003005412,1.2341735778065615,1.5050295510613063,0.7348993205919421,0.3332580754721944,1.6639450277501382,5.106453588871854,-0.9345419567612725,-0.31594654169938047,0.6378225083090472,-0.8309434988946349,-0.25557908848123395,0.5385907773537494,0.7348993205919421,3.6904275097045454,0.17280963840827135,-1.0406246148817728,-0.6307459142786708,-0.1372495529245524,-0.37714563952921315,-0.7632007073119792,-0.40806438662984673,0.22693649856222178,-0.37714563952921315,0.3594471701790773,-0.16653801380920247,-0.5339391468977894,0.30691434248850596,0.9459148854023514,0.9229538719151944,-0.28566029525923553,-0.28566029525923553,0.22693649856222178,-0.40806438662984673,0.17280963840827135,0.0063684354015670136,-1.3366301135330916,-0.07924492702588042,0.034544176031171075,0.30691434248850596,1.443957948969997,-0.25557908848123395,0.3854834577363446,0.30691434248850596,0.588482059091134,-0.1372495529245524,0.3332580754721944,-0.5659738392609449,-0.4705554931571856,-0.4705554931571856,-0.31594654169938047,-1.004980242603473,2.9317872528718985,0.8533559354124849,-0.07924492702588042 3367 Serine hydrolase activity 9 19 2.696559763842836 0.0070059824526709 P10619,Q9HB40,O14773,P42785,O75976,Q9H3G5,Q5JRX3,P67812,Q4J6C6 Functions GO Molecular function msigdb_gomf 190,34,70,21,183,27,375,93,347 70,183,190,2757,2603,849,21,3221,1070,1125,93,2335,439,347,375,1313,3130,27,34 2.9465065973455364,1.6639450277501382,1.6247393272059847,-0.6634903102109926,-0.5659738392609449,0.2804141068248859,3.8498324746709085,-1.1493154316371736,0.14549770029311399,0.11801732694304702,2.5151499572076714,-0.40806438662984673,0.7348993205919421,0.9459148854023514,0.8766756507402944,0.034544176031171075,-1.004980242603473,3.6904275097045454,3.525248122809391 3367 Rhoa gtpase cycle 14 49 2.679810676335767 0.0073663810355504 P30519,O75955,Q13190,P02786,Q14739,O15173,Q14254,Q15904,Q96HY6,P28288,P51572,Q86UP2,P41440,P27105 Processes and pathways Reactome Pathways msigdb_reactome 1,162,355,200,266,74,338,173,342,372,273,305,186,124 3064,74,1524,2303,1226,162,1397,926,200,2599,3147,124,372,1,186,640,397,2383,779,572,273,2387,3178,1549,2444,2847,355,1420,615,338,266,173,1686,1310,305,603,1696,3206,1368,342,2690,1213,1380,1922,1998,2352,877,1636,798 -0.9345419567612725,2.9317872528718985,-0.07924492702588042,-0.40806438662984673,0.06254274771127205,1.8550102756937976,-0.02198676428679048,0.22693649856222178,1.5851890116525102,-0.5659738392609449,-1.0406246148817728,2.19713106377011,0.8766756507402944,5.215090048676801,1.6639450277501382,0.46269330605308917,0.8299141117114622,-0.43919996831517205,0.3332580754721944,0.5385907773537494,1.1692778855749448,-0.43919996831517205,-1.0765587039609845,-0.07924492702588042,-0.4705554931571856,-0.7297139540963061,0.9229538719151944,-0.02198676428679048,0.488136037900703,0.9687588066338071,1.2126457954814382,1.722120594018782,-0.1372495529245524,0.034544176031171075,1.081263578277897,0.5134346459158582,-0.1372495529245524,-1.112787329154505,0.0063684354015670136,0.9687588066338071,-0.5982416058990344,0.09036639678564706,0.0063684354015670136,-0.22570012371921228,-0.25557908848123395,-0.40806438662984673,0.2804141068248859,-0.10815269963874782,0.3332580754721944 3367 Nucleotide transmembrane transporter activity 10 11 2.676088106051512 0.0074487060813934 Q99808,Q9HC21,P12235,Q8TB61,Q9BSK2,O43808,P05141,P12236,P41440,Q9H2D1 Functions GO Molecular function msigdb_gomf 259,324,447,44,209,549,553,307,186,61 549,553,447,307,186,599,44,259,209,61,324 0.5636060512556167,0.5636060512556167,0.7108269558541094,1.058987402257529,1.6639450277501382,0.5134346459158582,3.34039786005235,1.2555985905367433,1.5652826911718993,3.161755509768943,1.014100175743301 3367 Organophosphate ester transmembrane transporter activity 10 11 2.676088106051512 0.0074487060813934 Q99808,Q9HC21,P12235,Q8TB61,Q9BSK2,O43808,P05141,P12236,P41440,Q9H2D1 Functions GO Molecular function msigdb_gomf 259,324,447,44,209,549,553,307,186,61 549,553,447,307,186,599,44,259,209,61,324 0.5636060512556167,0.5636060512556167,0.7108269558541094,1.058987402257529,1.6639450277501382,0.5134346459158582,3.34039786005235,1.2555985905367433,1.5652826911718993,3.161755509768943,1.014100175743301 3367 Nucleotide transport 10 11 2.676088106051512 0.0074487060813934 Q99808,Q9HC21,P12235,Q8TB61,Q9BSK2,O43808,P05141,P12236,P41440,Q9H2D1 Processes and pathways GO Biological process msigdb_gobp 259,324,447,44,209,549,553,307,186,61 549,553,447,307,186,599,44,259,209,61,324 0.5636060512556167,0.5636060512556167,0.7108269558541094,1.058987402257529,1.6639450277501382,0.5134346459158582,3.34039786005235,1.2555985905367433,1.5652826911718993,3.161755509768943,1.014100175743301 3367 Proton transmembrane transporter activity 14 31 2.671958806319804 0.007540990508785 P13073,Q9UDW1,Q13423,P12235,P47985,O75964,P00403,P05141,P25705,Q9Y487,P06576,O95202,Q93050,P24539 Functions GO Molecular function msigdb_gomf 167,40,71,447,484,45,145,553,244,215,435,123,92,411 1938,45,123,145,553,435,970,1872,447,167,1797,1537,2377,411,244,3038,2318,1539,2976,484,3321,1073,1127,746,1548,71,92,2636,40,585,215 -0.25557908848123395,3.286174597616811,2.19713106377011,2.002235460610414,0.5636060512556167,0.7348993205919421,0.1999552233330087,-0.22570012371921228,0.7108269558541094,1.7795540517583925,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,0.7826588994764823,1.3192668476331657,-0.8997389788237078,-0.40806438662984673,-0.07924492702588042,-0.8309434988946349,0.6622900003005412,-1.5724386516725661,0.14549770029311399,0.11801732694304702,0.3594471701790773,-0.07924492702588042,2.9465065973455364,2.5793442451134623,-0.5659738392609449,3.380645404831543,0.5385907773537494,1.525203768425511 3367 Membrane microdomain 15 67 2.6607042168875905 0.0077977424217425 P09601,O75955,P35613,O14773,P09104,P41440,P05067,P21796,P27105,P13473,O15118,P25705,P50897,Q8WTV0,P19022 Localization GO Cellular component msigdb_gocc 0,162,165,70,327,186,90,13,124,210,85,244,26,60,286 1275,495,2363,70,85,3115,162,2023,3032,3261,1870,610,90,553,1531,3236,2370,2025,2105,327,0,1176,692,210,1796,973,1346,286,2655,436,773,13,2601,244,124,2763,2431,638,1185,742,2841,165,1288,186,2434,743,2321,26,2325,3178,1890,2613,1078,1304,858,338,598,828,60,3078,3280,678,2800,1579,2833,1159,527 0.034544176031171075,0.6378225083090472,-0.43919996831517205,2.9465065973455364,2.7359582136753127,-1.004980242603473,1.8550102756937976,-0.28566029525923553,-0.8997389788237078,-1.298525940794424,-0.22570012371921228,0.488136037900703,2.595251590463738,0.5636060512556167,-0.07924492702588042,-1.1861480785988963,-0.43919996831517205,-0.28566029525923553,-0.31594654169938047,0.9914868411153721,5.77073025593568,0.09036639678564706,0.41136873678446767,1.5452878774447738,-0.19602066046695343,0.1999552233330087,0.0063684354015670136,1.1254866370979533,-0.5982416058990344,0.7348993205919421,0.3332580754721944,4.220028343416946,-0.5659738392609449,1.3192668476331657,2.19713106377011,-0.6634903102109926,-0.4705554931571856,0.46269330605308917,0.09036639678564706,0.3594471701790773,-0.7297139540963061,1.7985369233817154,0.034544176031171075,1.6639450277501382,-0.4705554931571856,0.3594471701790773,-0.40806438662984673,3.6904275097045454,-0.40806438662984673,-1.0765587039609845,-0.22570012371921228,-0.5659738392609449,0.14549770029311399,0.034544176031171075,0.2804141068248859,0.9687588066338071,0.5134346459158582,0.30691434248850596,3.1896999455248927,-0.9345419567612725,-1.3366301135330916,0.4371047742428398,-0.6634903102109926,-0.07924492702588042,-0.6964784202356398,0.11801732694304702,0.6132203653820887 3367 Rough endoplasmic reticulum 9 33 2.6599542211759157 0.0078151272954629 Q07065,P04843,Q5BJF2,Q8TCT9,Q99442,Q9UQB8,Q9Y5M8,P05067,Q15041 Localization GO Cellular component msigdb_gocc 131,254,7,202,176,86,120,90,223 2093,1526,2101,254,1173,90,2600,2656,556,639,1237,897,3286,3222,2259,1807,852,1295,1738,3322,854,1812,1475,131,223,7,1429,202,274,176,766,86,120 -0.31594654169938047,-0.07924492702588042,-0.31594654169938047,1.2555985905367433,0.09036639678564706,2.595251590463738,-0.5659738392609449,-0.5982416058990344,0.5636060512556167,0.46269330605308917,0.06254274771127205,0.2537554699892711,-1.37506621536203,-1.1493154316371736,-0.37714563952921315,-0.19602066046695343,0.2804141068248859,0.034544176031171075,-0.16653801380920247,-1.5724386516725661,0.2804141068248859,-0.19602066046695343,-0.05052375805598644,2.144806762718082,1.4644074828289309,4.552178889851971,-0.02198676428679048,1.5851890116525102,1.1692778855749448,1.722120594018782,0.3594471701790773,2.7050655515155833,2.2316801472635333 3367 Sphingolipid metabolism 6 9 2.656040025095881 0.0079064229699485 O15269,P07602,P17900,Q06136,Q13510,P04062 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 220,65,169,77,78,118 220,965,250,118,65,169,77,78,685 1.4644074828289309,0.1999552233330087,1.276921824455599,2.248856101291637,3.0911332595741183,1.7413465847323417,2.8724277004854066,2.8724277004854066,0.4371047742428398 3367 Supranuclear gaze palsy 8 20 2.6541580846184853 0.0079506569262775 P07602,Q96RL7,P61916,Q9NZJ7,O15118,P04062,Q99720,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 65,297,197,276,85,118,28,192 2707,1276,85,118,65,2810,2975,192,2818,197,2501,1553,468,1092,297,1094,28,276,1519,369 -0.6307459142786708,0.034544176031171075,2.7359582136753127,2.248856101291637,3.0911332595741183,-0.6964784202356398,-0.8309434988946349,1.6247393272059847,-0.6964784202356398,1.605007630123358,-0.5021341373910327,-0.07924492702588042,0.6866243286062695,0.14549770029311399,1.1034296234289172,0.14549770029311399,3.665401627508389,1.1692778855749448,-0.05052375805598644,0.8998745416649946 3367 Polyneuropathy 10 18 2.6531189729550246 0.0079751755175152 P07602,O95831,Q9HC21,P60891,Q9NZJ7,O60313,P04066,Q8N2K0,O95721,Q15041 Drugs and Diseases Human Phenotype Ontology msigdb_hp 65,35,324,450,276,279,184,419,247,223 279,247,35,184,65,1399,3038,1666,450,518,223,618,1253,419,760,324,276,2801 1.1474357022138544,1.2981442560194676,3.512290521765781,1.6639450277501382,3.0911332595741183,-0.02198676428679048,-0.8997389788237078,-0.1372495529245524,0.7108269558541094,0.6132203653820887,1.4644074828289309,0.488136037900703,0.06254274771127205,0.7826588994764823,0.3594471701790773,1.014100175743301,1.1692778855749448,-0.6634903102109926 3367 Apical part of cell 23 51 2.649167739608984 0.0080690271417762 Q99808,Q13131,Q86UE4,P19022,O75955,Q8NCM8,P35241,Q9Y4G8,Q15043,P20020,P41440,P11166,Q14254,P30825,P05067,P53985,P08183,Q15154,P26038,Q16625,P05023,Q99538,P35222 Localization GO Cellular component msigdb_gocc 259,519,153,286,162,537,657,564,293,436,186,692,338,89,90,103,110,362,611,242,610,507,742 1855,2363,1391,924,162,2480,2484,610,90,110,807,1723,1065,692,3011,973,286,436,1537,2377,611,89,742,657,1539,2187,2976,186,103,1126,2322,1606,746,819,519,2943,857,338,293,362,1309,242,153,537,507,259,1218,1268,2084,564,2536 -0.22570012371921228,-0.43919996831517205,-0.02198676428679048,0.22693649856222178,1.8550102756937976,-0.5021341373910327,-0.5021341373910327,0.488136037900703,2.595251590463738,2.2999956417932186,0.30691434248850596,-0.16653801380920247,0.14549770029311399,0.41136873678446767,-0.8652075817496219,0.1999552233330087,1.1254866370979533,0.7348993205919421,-0.07924492702588042,-0.43919996831517205,0.488136037900703,2.6583280208911844,0.3594471701790773,0.4371047742428398,-0.07924492702588042,-0.34644068419145774,-0.8309434988946349,1.6639450277501382,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.10815269963874782,0.3594471701790773,0.30691434248850596,0.6132203653820887,-0.7969425638483784,0.2804141068248859,0.9687588066338071,1.1034296234289172,0.8998745416649946,0.034544176031171075,1.3402905479186136,1.9840930614703445,0.588482059091134,0.6378225083090472,1.2555985905367433,0.09036639678564706,0.06254274771127205,-0.28566029525923553,0.5636060512556167,-0.5021341373910327 3367 Neuron apoptotic process 10 50 2.6464348984531725 0.0081345161076644 P09601,O95831,Q92542,P05067,Q96A26,Q01105,Q9NR28,P04062,P50897,Q99720 Processes and pathways GO Biological process msigdb_gobp 0,35,227,90,175,181,213,118,26,28 3064,1648,1279,609,393,804,35,118,3255,2713,928,90,1532,1795,1065,0,2374,1534,257,742,2434,2891,659,2934,1666,1465,2256,743,2555,26,2037,2556,1606,2770,3306,181,1416,615,718,227,1092,175,3134,3280,507,28,762,213,960,1164 -0.9345419567612725,-0.1372495529245524,0.034544176031171075,0.488136037900703,0.8299141117114622,0.30691434248850596,3.512290521765781,2.248856101291637,-1.2607479309781038,-0.6307459142786708,0.22693649856222178,2.595251590463738,-0.07924492702588042,-0.19602066046695343,0.14549770029311399,5.77073025593568,-0.43919996831517205,-0.07924492702588042,1.2555985905367433,0.3594471701790773,-0.4705554931571856,-0.7632007073119792,0.4371047742428398,-0.7969425638483784,-0.1372495529245524,-0.05052375805598644,-0.37714563952921315,0.3594471701790773,-0.5339391468977894,3.6904275097045454,-0.28566029525923553,-0.5339391468977894,-0.10815269963874782,-0.6634903102109926,-1.4924261166507573,1.7028121530513547,-0.02198676428679048,0.488136037900703,0.3854834577363446,1.443957948969997,0.14549770029311399,1.722120594018782,-1.004980242603473,-1.3366301135330916,0.6378225083090472,3.665401627508389,0.3594471701790773,1.525203768425511,0.22693649856222178,0.11801732694304702 3367 Inner mitochondrial membrane protein complex 24 69 2.6397664495855624 0.00829631783983 O43676,O60830,Q99595,P00403,Q8IYU8,P24539,P13073,Q9UDW1,O75964,P06576,P12236,Q13505,Q9NX63,Q86Y39,O14925,O75431,Q9P0J0,Q9BUR5,P47985,P22695,Q16891,P25705,Q5XKP0,P14406 Localization GO Cellular component msigdb_gocc 4,9,11,145,534,411,167,40,45,435,307,58,461,340,464,97,230,367,484,482,363,244,502,252 3313,1389,464,4,9,2096,1057,97,2242,1938,45,2243,3233,2969,2024,145,435,970,1066,1872,307,167,252,2376,3192,1797,2430,482,411,244,3173,2604,3038,2031,2318,3220,484,3321,3095,661,1073,1127,58,2506,2336,363,826,698,502,784,340,534,1493,834,705,11,1507,1376,367,2797,878,2156,461,230,40,733,734,565,1110 -1.5322507832020744,-0.02198676428679048,0.6866243286062695,4.744465578955981,4.521067264147013,-0.31594654169938047,0.14549770029311399,2.4171181472402936,-0.37714563952921315,-0.25557908848123395,3.286174597616811,-0.37714563952921315,-1.1861480785988963,-0.8309434988946349,-0.28566029525923553,2.002235460610414,0.7348993205919421,0.1999552233330087,0.14549770029311399,-0.22570012371921228,1.058987402257529,1.7795540517583925,1.276921824455599,-0.43919996831517205,-1.112787329154505,-0.19602066046695343,-0.4705554931571856,0.6622900003005412,0.7826588994764823,1.3192668476331657,-1.0765587039609845,-0.5659738392609449,-0.8997389788237078,-0.28566029525923553,-0.40806438662984673,-1.1493154316371736,0.6622900003005412,-1.5724386516725661,-0.969620885690122,0.4371047742428398,0.14549770029311399,0.11801732694304702,3.2036080031326675,-0.5021341373910327,-0.40806438662984673,0.8998745416649946,0.30691434248850596,0.41136873678446767,0.6378225083090472,0.3332580754721944,0.9687588066338071,0.588482059091134,-0.05052375805598644,0.30691434248850596,0.41136873678446767,4.253245556056843,-0.05052375805598644,0.0063684354015670136,0.8998745416649946,-0.6634903102109926,0.2804141068248859,-0.31594654169938047,0.7108269558541094,1.4234149403548129,3.380645404831543,0.3854834577363446,0.3854834577363446,0.5636060512556167,0.14549770029311399 3367 Abnormal conjunctiva morphology 9 29 2.6321873367732063 0.0084837069433079 P10619,P28070,Q9NZ08,P02786,Q14739,P06280,Q13510,P04066,O00462 Drugs and Diseases Human Phenotype Ontology msigdb_hp 190,36,168,200,266,139,78,184,126 126,1591,302,200,184,3087,139,190,2108,1286,975,2430,2248,36,3150,848,743,2978,1124,1743,3290,78,266,1307,425,1501,1318,1154,168 2.1797569087503486,-0.10815269963874782,1.081263578277897,1.5851890116525102,1.6639450277501382,-0.969620885690122,2.074084118777206,1.6247393272059847,-0.31594654169938047,0.034544176031171075,0.1999552233330087,-0.4705554931571856,-0.37714563952921315,3.473195069920084,-1.0406246148817728,0.2804141068248859,0.3594471701790773,-0.8309434988946349,0.11801732694304702,-0.16653801380920247,-1.4138401674883982,2.8724277004854066,1.2126457954814382,0.034544176031171075,0.7588428378146155,-0.05052375805598644,0.034544176031171075,0.11801732694304702,1.7795540517583925 3367 Transition metal ion homeostasis 8 24 2.6195348254312205 0.0088049781861823 P09601,P30519,Q658P3,P02786,Q15904,Q8N511,Q9Y487,P05067 Processes and pathways GO Biological process msigdb_gobp 0,1,129,200,173,48,215,90 2171,1452,654,593,1015,568,3253,200,3255,90,0,774,1,2491,2976,746,3290,2042,293,173,129,48,1512,215 -0.34644068419145774,-0.05052375805598644,0.4371047742428398,0.5134346459158582,0.17280963840827135,0.5385907773537494,-1.2607479309781038,1.5851890116525102,-1.2607479309781038,2.595251590463738,5.77073025593568,0.3332580754721944,5.215090048676801,-0.5021341373910327,-0.8309434988946349,0.3594471701790773,-1.4138401674883982,-0.28566029525923553,1.1034296234289172,1.722120594018782,2.16231565108635,3.286174597616811,-0.05052375805598644,1.525203768425511 3367 Abnormal biliary tract morphology 10 25 2.618956620377136 0.0088199162596653 P09601,P07602,O43933,Q14108,Q14739,Q10713,Q9NZJ7,Q9NSD9,P04062,Q5XKP0 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,65,132,5,266,398,276,474,118,502 738,132,805,118,65,0,893,555,3302,849,1666,1292,398,696,5,266,502,1501,1983,726,474,276,1930,733,2474 0.3594471701790773,2.12722970929693,0.30691434248850596,2.248856101291637,3.0911332595741183,5.77073025593568,0.2537554699892711,0.5636060512556167,-1.4924261166507573,0.2804141068248859,-0.1372495529245524,0.034544176031171075,0.8299141117114622,0.41136873678446767,4.744465578955981,1.2126457954814382,0.6378225083090472,-0.05052375805598644,-0.25557908848123395,0.3854834577363446,0.6866243286062695,1.1692778855749448,-0.22570012371921228,0.3854834577363446,-0.4705554931571856 3367 Active transmembrane transporter activity 21 59 2.617894597586403 0.008847412884104 O43676,P51798,P00403,Q9UBX3,P13073,Q15043,Q9UDW1,P16615,P05141,P20020,P06576,P12236,P41440,P12235,Q9P0J0,P53985,P47985,P08183,Q9HD20,P28288,O95202 Functions GO Molecular function msigdb_gomf 4,516,145,18,167,293,40,290,553,436,435,307,186,447,230,103,484,110,115,372,123 3313,1389,1588,4,1015,2096,1057,2242,2243,3233,123,2969,2024,145,610,553,435,110,807,970,1872,447,307,167,290,3192,436,1797,1537,2377,372,3173,3038,1539,2976,186,484,3095,516,661,1071,103,2322,746,1548,980,293,906,2506,2336,1493,2636,115,1710,230,18,40,585,1110 -1.5322507832020744,-0.02198676428679048,-0.10815269963874782,4.744465578955981,0.17280963840827135,-0.31594654169938047,0.14549770029311399,-0.37714563952921315,-0.37714563952921315,-1.1861480785988963,2.19713106377011,-0.8309434988946349,-0.28566029525923553,2.002235460610414,0.488136037900703,0.5636060512556167,0.7348993205919421,2.2999956417932186,0.30691434248850596,0.1999552233330087,-0.22570012371921228,0.7108269558541094,1.058987402257529,1.7795540517583925,1.1034296234289172,-1.112787329154505,0.7348993205919421,-0.19602066046695343,-0.07924492702588042,-0.43919996831517205,0.8766756507402944,-1.0765587039609845,-0.8997389788237078,-0.07924492702588042,-0.8309434988946349,1.6639450277501382,0.6622900003005412,-0.969620885690122,0.6132203653820887,0.4371047742428398,0.14549770029311399,2.40057096317167,-0.40806438662984673,0.3594471701790773,-0.07924492702588042,0.1999552233330087,1.1034296234289172,0.2537554699892711,-0.5021341373910327,-0.40806438662984673,-0.05052375805598644,-0.5659738392609449,2.283013353361886,-0.1372495529245524,1.4234149403548129,4.015494309311654,3.380645404831543,0.5385907773537494,0.14549770029311399 3367 Secondary active transmembrane transporter activity 8 17 2.617468224099444 0.0088584735632462 P53985,Q15043,P12235,P51798,Q9UBX3,P12236,P41440,O95202 Functions GO Molecular function msigdb_gomf 103,293,447,516,18,307,186,123 123,553,807,447,307,186,516,1071,103,2322,1548,980,293,906,1493,2636,18 2.19713106377011,0.5636060512556167,0.30691434248850596,0.7108269558541094,1.058987402257529,1.6639450277501382,0.6132203653820887,0.14549770029311399,2.40057096317167,-0.40806438662984673,-0.07924492702588042,0.1999552233330087,1.1034296234289172,0.2537554699892711,-0.05052375805598644,-0.5659738392609449,4.015494309311654 3367 Agitation 12 33 2.609723217590095 0.0090615506243096 P42858,Q14203,P48449,Q15165,P42892,P52732,P04062,P35610,P05067,Q92804,O96008,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 344,468,98,135,43,304,118,308,90,219,466,192 1527,926,466,118,90,2309,1657,1176,2882,308,192,344,43,1186,98,976,2037,304,2818,518,1191,2501,1553,468,1134,135,1487,1753,1976,219,1209,3280,3026 -0.07924492702588042,0.22693649856222178,0.6866243286062695,2.248856101291637,2.595251590463738,-0.40806438662984673,-0.1372495529245524,0.09036639678564706,-0.7632007073119792,1.058987402257529,1.6247393272059847,0.9459148854023514,3.34039786005235,0.09036639678564706,2.4171181472402936,0.1999552233330087,-0.28566029525923553,1.081263578277897,-0.6964784202356398,0.6132203653820887,0.09036639678564706,-0.5021341373910327,-0.07924492702588042,0.6866243286062695,0.11801732694304702,2.0918689378538042,-0.05052375805598644,-0.16653801380920247,-0.25557908848123395,1.4847644010892234,0.09036639678564706,-1.3366301135330916,-0.8652075817496219 3367 Coated vesicle membrane 15 53 2.606636598265333 0.0091436344866437 P24390,Q13190,P11717,Q14108,P02786,Q9Y3B3,P10321,P01889,P49755,Q8N511,P09496,P04439,P20645,Q9Y678,P35606 Localization GO Cellular component msigdb_gocc 2,355,217,5,200,75,481,302,437,48,554,333,185,391,497 2171,1225,3347,801,1653,691,2544,2367,1281,1230,1170,1282,1062,302,200,333,554,1594,481,1940,217,773,185,2,497,1949,572,437,2723,1670,813,2258,2896,1737,1956,817,355,5,2202,1360,1556,1307,48,835,795,2001,2468,2469,2748,1520,75,391,1586 -0.34644068419145774,0.06254274771127205,-1.8215870556151397,0.30691434248850596,-0.1372495529245524,0.41136873678446767,-0.5339391468977894,-0.43919996831517205,0.034544176031171075,0.06254274771127205,0.09036639678564706,0.034544176031171075,0.14549770029311399,1.081263578277897,1.5851890116525102,0.9687588066338071,0.5636060512556167,-0.10815269963874782,0.6622900003005412,-0.25557908848123395,1.5050295510613063,0.3332580754721944,1.6639450277501382,5.106453588871854,0.6378225083090472,-0.25557908848123395,0.5385907773537494,0.7348993205919421,-0.6307459142786708,-0.1372495529245524,0.30691434248850596,-0.37714563952921315,-0.7632007073119792,-0.16653801380920247,-0.25557908848123395,0.30691434248850596,0.9229538719151944,4.744465578955981,-0.34644068419145774,0.0063684354015670136,-0.07924492702588042,0.034544176031171075,3.286174597616811,0.30691434248850596,0.3332580754721944,-0.25557908848123395,-0.4705554931571856,-0.4705554931571856,-0.6307459142786708,-0.05052375805598644,2.9317872528718985,0.8533559354124849,-0.07924492702588042 3367 Regulation of lipid metabolic process 20 53 2.605906336610501 0.0091631514928038 P31751,Q13131,Q9NZJ7,Q2T9J0,Q8WTV0,P30536,Q9UBM7,P07602,Q96G23,P61916,Q6IAA8,Q13510,P34913,P16435,Q96N66,P50416,Q15120,Q92604,P42345,O75844 Processes and pathways GO Biological process msigdb_gobp 257,519,276,439,60,191,325,65,66,197,598,78,207,222,101,485,618,245,498,127 3318,1788,2543,1790,127,3145,2023,1171,2102,2484,610,65,1067,222,1346,191,257,207,2433,498,1466,485,3304,1606,197,2441,981,2396,519,78,1421,2043,2727,618,1245,439,2822,598,1367,1911,60,245,2143,66,101,1210,1507,276,325,2162,1450,1579,3312 -1.5724386516725661,-0.19602066046695343,-0.5339391468977894,-0.19602066046695343,2.16231565108635,-1.0406246148817728,-0.28566029525923553,0.09036639678564706,-0.31594654169938047,-0.5021341373910327,0.488136037900703,3.0911332595741183,0.14549770029311399,1.4644074828289309,0.0063684354015670136,1.6247393272059847,1.2555985905367433,1.5652826911718993,-0.4705554931571856,0.6378225083090472,-0.05052375805598644,0.6622900003005412,-1.4924261166507573,-0.10815269963874782,1.605007630123358,-0.4705554931571856,0.1999552233330087,-0.43919996831517205,0.6132203653820887,2.8724277004854066,-0.02198676428679048,-0.28566029525923553,-0.6307459142786708,0.488136037900703,0.06254274771127205,0.7348993205919421,-0.6964784202356398,0.5134346459158582,0.0063684354015670136,-0.22570012371921228,3.1896999455248927,1.3192668476331657,-0.31594654169938047,3.0911332595741183,2.4171181472402936,0.09036639678564706,-0.05052375805598644,1.1692778855749448,1.014100175743301,-0.31594654169938047,-0.02198676428679048,-0.07924492702588042,-1.4924261166507573 3367 Phospholipid binding 9 96 2.5965991225519214 0.0094151735626897 P07602,Q14108,P21796,Q9UM22,P45880,P50897,Q8WTV0,Q9Y5X1,Q8NCC3 Functions GO Molecular function msigdb_gomf 65,5,13,14,19,26,60,30,63 589,2425,1225,735,495,70,392,1391,2018,924,279,3282,465,1227,2484,2370,65,2309,1655,1656,2653,1940,1658,929,13,2314,3151,2814,2382,19,2494,779,2435,26,976,979,2437,1547,518,695,1300,1078,820,2042,1242,2446,5,2202,988,3224,361,1360,2678,577,2053,2737,911,1627,63,913,60,1257,1497,2142,3346,3109,2692,1508,2693,1378,491,1327,1213,761,289,1214,1330,877,2912,276,880,2294,2998,1579,547,1847,14,2870,1159,960,511,2966,1932,564,30,567 0.5134346459158582,-0.4705554931571856,0.06254274771127205,0.3594471701790773,0.6378225083090472,2.9465065973455364,0.8299141117114622,-0.02198676428679048,-0.28566029525923553,0.22693649856222178,1.1474357022138544,-1.37506621536203,0.6866243286062695,0.06254274771127205,-0.5021341373910327,-0.43919996831517205,3.0911332595741183,-0.40806438662984673,-0.1372495529245524,-0.1372495529245524,-0.5982416058990344,-0.25557908848123395,-0.1372495529245524,0.22693649856222178,4.220028343416946,-0.40806438662984673,-1.0406246148817728,-0.6964784202356398,-0.43919996831517205,3.9215673900004977,-0.5021341373910327,0.3332580754721944,-0.4705554931571856,3.6904275097045454,0.1999552233330087,0.1999552233330087,-0.4705554931571856,-0.07924492702588042,0.6132203653820887,0.41136873678446767,0.034544176031171075,0.14549770029311399,0.30691434248850596,-0.28566029525923553,0.06254274771127205,-0.4705554931571856,4.744465578955981,-0.34644068419145774,0.1999552233330087,-1.1493154316371736,0.8998745416649946,0.0063684354015670136,-0.5982416058990344,0.5385907773537494,-0.28566029525923553,-0.6307459142786708,0.2537554699892711,-0.10815269963874782,3.1336381893089387,0.2537554699892711,3.1896999455248927,0.06254274771127205,-0.05052375805598644,-0.31594654169938047,-1.7790704476183576,-0.969620885690122,-0.5982416058990344,-0.05052375805598644,-0.5982416058990344,0.0063684354015670136,0.6622900003005412,0.034544176031171075,0.09036639678564706,0.3594471701790773,1.1254866370979533,0.09036639678564706,0.034544176031171075,0.2804141068248859,-0.7632007073119792,1.1692778855749448,0.2804141068248859,-0.37714563952921315,-0.8309434988946349,-0.07924492702588042,0.588482059091134,-0.19602066046695343,4.1865682400285555,-0.7297139540963061,0.11801732694304702,0.22693649856222178,0.6378225083090472,-0.7969425638483784,-0.22570012371921228,0.5636060512556167,3.614933961940769,0.5636060512556167 3367 Cherry red spot of the macula 6 9 2.591877156895876 0.0095453848805138 P10619,P07602,P16278,P17900,Q13510,P06865 Drugs and Diseases Human Phenotype Ontology msigdb_hp 190,65,41,169,78,81 81,65,1064,190,2758,41,169,78,276 2.781905953857426,3.0911332595741183,0.14549770029311399,1.6247393272059847,-0.6634903102109926,3.367269068562799,1.7413465847323417,2.8724277004854066,1.1692778855749448 3367 Spectrin repeat [IPR002017] 7 10 2.590993509124057 0.0095699296512223 Q9UPN3,P46939,O43707,P12814,Q13813,Q8WXH0,Q03001 Sequence InterPro Repeat interpro_repeat 494,413,410,448,292,331,423 1391,410,1397,448,413,518,423,292,331,494 -0.02198676428679048,0.7826588994764823,-0.02198676428679048,0.7108269558541094,0.7826588994764823,0.6132203653820887,0.7588428378146155,1.1034296234289172,0.9914868411153721,0.6622900003005412 3367 Protein localization to mitochondrion 21 52 2.5890262140264007 0.0096247767262029 Q9NS69,O60830,O43615,Q99595,Q10713,Q13131,P51572,O14737,O95831,Q9Y512,O00429,Q9Y6C9,P30536,P49840,P55786,O96008,O14925,Q9P0J0,Q15070,Q9NX47,Q5JRX3 Processes and pathways GO Biological process msigdb_gobp 3,9,513,11,398,519,273,284,35,565,300,306,191,320,84,466,464,230,360,510,375 1854,2171,300,284,464,513,9,2595,2649,3254,2305,2369,35,466,969,3034,971,2655,2759,1234,191,2379,2432,572,320,273,1605,84,2846,398,519,360,3045,826,698,375,2344,1090,1506,11,3056,2797,3,510,230,2746,733,3299,1386,565,1853,306 -0.22570012371921228,-0.34644068419145774,1.081263578277897,1.1254866370979533,0.6866243286062695,0.6132203653820887,4.521067264147013,-0.5659738392609449,-0.5982416058990344,-1.2607479309781038,-0.40806438662984673,-0.43919996831517205,3.512290521765781,0.6866243286062695,0.1999552233330087,-0.8997389788237078,0.1999552233330087,-0.5982416058990344,-0.6634903102109926,0.06254274771127205,1.6247393272059847,-0.43919996831517205,-0.4705554931571856,0.5385907773537494,1.014100175743301,1.1692778855749448,-0.10815269963874782,2.7513259355917703,-0.7297139540963061,0.8299141117114622,0.6132203653820887,0.8998745416649946,-0.8997389788237078,0.30691434248850596,0.41136873678446767,0.8766756507402944,-0.40806438662984673,0.14549770029311399,-0.05052375805598644,4.253245556056843,-0.8997389788237078,-0.6634903102109926,4.832811783410612,0.6378225083090472,1.4234149403548129,-0.6307459142786708,0.3854834577363446,-1.45295805178107,0.0063684354015670136,0.5636060512556167,-0.19602066046695343,1.081263578277897 3367 Monooxygenase activity 6 9 2.5878977144478754 0.0096563649852512 P09601,P30519,Q6UW02,Q15800,Q9BU89,Q16850 Functions GO Molecular function msigdb_gomf 0,1,226,69,157,94 2098,0,1,814,339,69,94,226,157 -0.31594654169938047,5.77073025593568,5.215090048676801,0.30691434248850596,0.9687588066338071,2.9611783576004687,2.482708122078919,1.443957948969997,1.9475878367392199 3367 EF-hand domain pair [IPR011992] 16 47 2.5836250142665285 0.0097768027715405 P46939,Q9UPN3,O43707,O43852,O75746,O75071,P12814,Q13813,Q03001,Q02818,P80303,Q9BRK5,Q9Y680,Q9UJS0,Q14257,O95202 Sequence InterPro Superfamily interpro_homologous_superfamily 413,494,410,196,381,68,448,292,423,46,15,148,178,546,151,123 410,196,68,2544,381,123,2485,2549,448,2838,972,1346,1181,2601,2491,2887,810,778,413,2897,15,46,423,292,151,2945,1361,1898,599,1314,2573,2056,534,946,1367,2408,916,3078,1376,148,649,1042,881,2469,546,494,178 0.7826588994764823,1.605007630123358,2.975802844788199,-0.5339391468977894,0.8533559354124849,2.19713106377011,-0.5021341373910327,-0.5339391468977894,0.7108269558541094,-0.7297139540963061,0.1999552233330087,0.0063684354015670136,0.09036639678564706,-0.5659738392609449,-0.5021341373910327,-0.7632007073119792,0.30691434248850596,0.3332580754721944,0.7826588994764823,-0.7632007073119792,4.164124775027304,3.286174597616811,0.7588428378146155,1.1034296234289172,1.9840930614703445,-0.7969425638483784,0.0063684354015670136,-0.22570012371921228,0.5134346459158582,0.034544176031171075,-0.5339391468977894,-0.28566029525923553,0.588482059091134,0.22693649856222178,0.0063684354015670136,-0.43919996831517205,0.2537554699892711,-0.9345419567612725,0.0063684354015670136,2.002235460610414,0.46269330605308917,0.17280963840827135,0.2804141068248859,-0.4705554931571856,0.588482059091134,0.6622900003005412,1.722120594018782 3367 Abnormal epiphyseal ossification 9 17 2.5796131664130724 0.0098911044331488 Q9UBM7,O43933,P38435,O75381,Q15125,Q14739,Q96HY6,Q96L58,Q2M1P5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 325,132,383,319,166,266,342,378,253 713,132,2877,319,1176,383,449,266,2333,166,1247,253,871,342,378,325,882 0.3854834577363446,2.12722970929693,-0.7632007073119792,1.014100175743301,0.09036639678564706,0.8533559354124849,0.7108269558541094,1.2126457954814382,-0.40806438662984673,1.7985369233817154,0.06254274771127205,1.276921824455599,0.2804141068248859,0.9687588066338071,0.8766756507402944,1.014100175743301,0.2804141068248859 3367 Monovalent inorganic cation homeostasis 11 25 2.577384235101204 0.0099551221300357 O75503,Q92544,Q96PU5,Q15904,Q9Y5X3,Q8N511,Q9Y487,P06576,P50897,Q93050,Q9UI12 Processes and pathways GO Biological process msigdb_gobp 102,489,268,173,567,48,215,435,26,92,585 102,891,1870,610,435,2180,2763,2431,26,1019,1126,2322,746,1417,173,48,489,92,1318,268,2162,585,215,567,2536 2.40057096317167,0.2537554699892711,-0.22570012371921228,0.488136037900703,0.7348993205919421,-0.34644068419145774,-0.6634903102109926,-0.4705554931571856,3.6904275097045454,0.17280963840827135,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.02198676428679048,1.722120594018782,3.286174597616811,0.6622900003005412,2.5793442451134623,0.034544176031171075,1.2126457954814382,-0.31594654169938047,0.5385907773537494,1.525203768425511,0.5636060512556167,-0.5021341373910327 3367 Abnormal tissue metabolite concentration 7 15 2.572609409876544 0.0100935047321952 Q658P3,P07602,O43933,P06280,P17900,P06865,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,65,132,139,169,81,276 738,132,319,139,81,65,1064,555,169,1292,449,129,3316,276,733 0.3594471701790773,2.12722970929693,1.014100175743301,2.074084118777206,2.781905953857426,3.0911332595741183,0.14549770029311399,0.5636060512556167,1.7413465847323417,0.034544176031171075,0.7108269558541094,2.16231565108635,-1.5322507832020744,1.1692778855749448,0.3854834577363446 3367 Protein transmembrane transport 12 24 2.5723926469934204 0.0100998273411945 Q9NS69,O43933,O95831,O75381,O60830,Q15629,Q99595,P49755,Q99442,O96008,O14925,P31751 Processes and pathways GO Biological process msigdb_gobp 3,132,35,319,9,10,11,437,176,466,464,257 464,513,132,9,319,2649,35,466,3034,2599,257,437,3286,3222,2194,852,10,826,2737,176,11,2797,3,766 0.6866243286062695,0.6132203653820887,2.12722970929693,4.521067264147013,1.014100175743301,-0.5982416058990344,3.512290521765781,0.6866243286062695,-0.8997389788237078,-0.5659738392609449,1.2555985905367433,0.7348993205919421,-1.37506621536203,-1.1493154316371736,-0.34644068419145774,0.2804141068248859,4.2752571823438945,0.30691434248850596,-0.6307459142786708,1.722120594018782,4.253245556056843,-0.6634903102109926,4.832811783410612,0.3594471701790773 3367 EF-hand domain [IPR002048] 15 42 2.563102624468037 0.0103741379455797 Q9UPN3,O43707,O43852,O75746,O75071,P12814,Q13813,Q03001,Q02818,P80303,Q9BRK5,Q9Y680,Q9UJS0,Q14257,O95202 Sequence InterPro Domain interpro_domain 494,410,196,381,68,448,292,423,46,15,148,178,546,151,123 410,196,68,2544,381,123,2485,2549,448,2838,972,1346,1181,2491,2887,810,778,2897,15,46,423,292,151,2945,1361,1898,599,2573,2056,534,1367,2408,916,3078,1376,148,649,881,2469,546,494,178 0.7826588994764823,1.605007630123358,2.975802844788199,-0.5339391468977894,0.8533559354124849,2.19713106377011,-0.5021341373910327,-0.5339391468977894,0.7108269558541094,-0.7297139540963061,0.1999552233330087,0.0063684354015670136,0.09036639678564706,-0.5021341373910327,-0.7632007073119792,0.30691434248850596,0.3332580754721944,-0.7632007073119792,4.164124775027304,3.286174597616811,0.7588428378146155,1.1034296234289172,1.9840930614703445,-0.7969425638483784,0.0063684354015670136,-0.22570012371921228,0.5134346459158582,-0.5339391468977894,-0.28566029525923553,0.588482059091134,0.0063684354015670136,-0.43919996831517205,0.2537554699892711,-0.9345419567612725,0.0063684354015670136,2.002235460610414,0.46269330605308917,0.2804141068248859,-0.4705554931571856,0.588482059091134,0.6622900003005412,1.722120594018782 3367 Vascular process in circulatory system 8 32 2.5597207607904964 0.0104756298045585 Q9HB40,P53985,P02786,P42892,P08183,Q16625,P30825,P41440 Processes and pathways GO Biological process msigdb_gobp 34,103,200,43,110,242,89,186 735,2363,1526,1226,3330,594,200,3255,110,692,2599,436,89,186,43,1666,1465,103,2322,818,819,1476,1963,615,2049,906,242,1822,2142,259,34,877 0.3594471701790773,-0.43919996831517205,-0.07924492702588042,0.06254274771127205,-1.6129965081754174,0.5134346459158582,1.5851890116525102,-1.2607479309781038,2.2999956417932186,0.41136873678446767,-0.5659738392609449,0.7348993205919421,2.6583280208911844,1.6639450277501382,3.34039786005235,-0.1372495529245524,-0.05052375805598644,2.40057096317167,-0.40806438662984673,0.30691434248850596,0.30691434248850596,-0.05052375805598644,-0.25557908848123395,0.488136037900703,-0.28566029525923553,0.2537554699892711,1.3402905479186136,-0.19602066046695343,-0.31594654169938047,1.2555985905367433,3.525248122809391,0.2804141068248859 3367 Lipid binding 27 145 2.5534405356975487 0.0106664490348116 Q14108,Q14849,Q9BQE5,P21796,Q9UM22,P45880,Q9NZJ7,O15254,O60313,P50897,Q9H490,Q9Y5X1,P28070,O00429,A6NIH7,Q8WTV0,Q8NCC3,P30536,P07602,P61916,O14773,O15173,O15118,P11717,Q15067,O00264,P04062 Functions GO Molecular function msigdb_gomf 5,6,8,13,14,19,276,149,279,26,289,30,36,300,57,60,63,191,65,197,70,74,85,217,232,106,118 589,2425,57,106,1225,300,735,495,1113,70,392,1391,85,74,149,2018,924,279,3282,465,1227,2023,1281,118,2484,610,2370,65,2309,1655,1656,2653,3034,1940,1658,2550,217,3117,929,13,2314,2929,3172,36,612,1184,3151,191,2814,308,2382,383,19,2494,779,2435,26,976,2662,3248,979,2437,2608,2818,1805,449,197,3178,1547,1472,518,695,1300,2613,1078,820,2042,1242,2446,5,2202,6,988,3224,232,361,1360,2678,577,1201,2053,2737,911,1627,63,868,913,60,1257,1497,2142,835,1700,3346,1096,791,3109,1507,2692,2955,1508,8,2693,1378,1990,491,1327,1213,761,289,1214,582,1330,650,877,2912,276,880,2294,2998,1579,547,1847,14,2870,1159,960,651,511,3299,2966,1932,564,30,567 0.5134346459158582,-0.4705554931571856,3.2036080031326675,2.333769977004763,0.06254274771127205,1.081263578277897,0.3594471701790773,0.6378225083090472,0.11801732694304702,2.9465065973455364,0.8299141117114622,-0.02198676428679048,2.7359582136753127,2.9317872528718985,1.9840930614703445,-0.28566029525923553,0.22693649856222178,1.1474357022138544,-1.37506621536203,0.6866243286062695,0.06254274771127205,-0.28566029525923553,0.034544176031171075,2.248856101291637,-0.5021341373910327,0.488136037900703,-0.43919996831517205,3.0911332595741183,-0.40806438662984673,-0.1372495529245524,-0.1372495529245524,-0.5982416058990344,-0.8997389788237078,-0.25557908848123395,-0.1372495529245524,-0.5339391468977894,1.5050295510613063,-1.004980242603473,0.22693649856222178,4.220028343416946,-0.40806438662984673,-0.7969425638483784,-1.0765587039609845,3.473195069920084,0.488136037900703,0.09036639678564706,-1.0406246148817728,1.6247393272059847,-0.6964784202356398,1.058987402257529,-0.43919996831517205,0.8533559354124849,3.9215673900004977,-0.5021341373910327,0.3332580754721944,-0.4705554931571856,3.6904275097045454,0.1999552233330087,-0.5982416058990344,-1.2232904675772427,0.1999552233330087,-0.4705554931571856,-0.5659738392609449,-0.6964784202356398,-0.19602066046695343,0.7108269558541094,1.605007630123358,-1.0765587039609845,-0.07924492702588042,-0.05052375805598644,0.6132203653820887,0.41136873678446767,0.034544176031171075,-0.5659738392609449,0.14549770029311399,0.30691434248850596,-0.28566029525923553,0.06254274771127205,-0.4705554931571856,4.744465578955981,-0.34644068419145774,4.664482621298005,0.1999552233330087,-1.1493154316371736,1.402777585756001,0.8998745416649946,0.0063684354015670136,-0.5982416058990344,0.5385907773537494,0.09036639678564706,-0.28566029525923553,-0.6307459142786708,0.2537554699892711,-0.10815269963874782,3.1336381893089387,0.2804141068248859,0.2537554699892711,3.1896999455248927,0.06254274771127205,-0.05052375805598644,-0.31594654169938047,0.30691434248850596,-0.1372495529245524,-1.7790704476183576,0.14549770029311399,0.3332580754721944,-0.969620885690122,-0.05052375805598644,-0.5982416058990344,-0.7969425638483784,-0.05052375805598644,4.552178889851971,-0.5982416058990344,0.0063684354015670136,-0.25557908848123395,0.6622900003005412,0.034544176031171075,0.09036639678564706,0.3594471701790773,1.1254866370979533,0.09036639678564706,0.5385907773537494,0.034544176031171075,0.46269330605308917,0.2804141068248859,-0.7632007073119792,1.1692778855749448,0.2804141068248859,-0.37714563952921315,-0.8309434988946349,-0.07924492702588042,0.588482059091134,-0.19602066046695343,4.1865682400285555,-0.7297139540963061,0.11801732694304702,0.22693649856222178,0.46269330605308917,0.6378225083090472,-1.45295805178107,-0.7969425638483784,-0.22570012371921228,0.5636060512556167,3.614933961940769,0.5636060512556167 3367 membrane trafficking regulatory protein 8 21 2.55170792674641 0.0107196339788795 P24390,Q14108,P11279,Q15075,P13473,O43760,Q15833,Q8WTV0 Functions Panther Protein class panther_protein_class 2,5,261,361,210,216,501,60 1855,887,495,216,926,261,210,2,5,361,3277,501,60,914,1696,1318,674,1921,2639,1155,2293 -0.22570012371921228,0.2537554699892711,0.6378225083090472,1.5050295510613063,0.22693649856222178,1.2341735778065615,1.5452878774447738,5.106453588871854,4.744465578955981,0.8998745416649946,-1.3366301135330916,0.6378225083090472,3.1896999455248927,0.2537554699892711,-0.1372495529245524,0.034544176031171075,0.4371047742428398,-0.22570012371921228,-0.5659738392609449,0.11801732694304702,-0.37714563952921315 3367 Glycosyltransferase 9 31 2.549007782025529 0.0108029889607281 O43505,Q8TCJ2,Q10472,P43490,P04062,Q2TAA5,P46977,Q86SF2,Q13126 Functions Protein Atlas Molecular function protein_atlas_molecular_function 195,341,208,335,118,248,188,317,95 2018,195,1526,1654,2103,2927,118,1117,2652,2374,2654,1873,1179,1662,335,188,1416,1357,664,208,95,248,1624,317,2346,341,378,630,1918,1440,1006 -0.28566029525923553,1.605007630123358,-0.07924492702588042,-0.1372495529245524,-0.31594654169938047,-0.7969425638483784,2.248856101291637,0.11801732694304702,-0.5982416058990344,-0.43919996831517205,-0.5982416058990344,-0.22570012371921228,0.09036639678564706,-0.1372495529245524,0.9687588066338071,1.6443848730963768,-0.02198676428679048,0.0063684354015670136,0.4371047742428398,1.5652826911718993,2.4663995632740083,1.2981442560194676,-0.10815269963874782,1.0365999791862452,-0.40806438662984673,0.9687588066338071,0.8766756507402944,0.488136037900703,-0.22570012371921228,-0.02198676428679048,0.1999552233330087 3367 N glycan biosynthesis 6 15 2.545935302523959 0.0108985385476121 P04843,Q16706,O60476,Q86YN1,Q2TAA5,P46977 Processes and pathways KEGG Pathways msigdb_kegg 254,294,235,174,248,188 235,1654,2544,254,1173,1601,188,2196,2126,1746,294,248,174,341,630 1.3820450016487578,-0.1372495529245524,-0.5339391468977894,1.2555985905367433,0.09036639678564706,-0.10815269963874782,1.6443848730963768,-0.34644068419145774,-0.31594654169938047,-0.16653801380920247,1.1034296234289172,1.2981442560194676,1.722120594018782,0.9687588066338071,0.488136037900703 3367 Delusions 10 22 2.5456142392155305 0.0109085663593362 P42858,P07602,Q96RL7,Q9BQE5,P21964,O00754,Q9NZJ7,Q9UJS0,Q96DF8,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 344,65,297,8,396,480,276,546,309,118 480,738,118,65,2372,555,396,3071,2187,344,1461,1733,1419,1681,2455,309,297,8,1443,276,2531,546 0.6622900003005412,0.3594471701790773,2.248856101291637,3.0911332595741183,-0.43919996831517205,0.5636060512556167,0.8299141117114622,-0.9345419567612725,-0.34644068419145774,0.9459148854023514,-0.05052375805598644,-0.16653801380920247,-0.02198676428679048,-0.1372495529245524,-0.4705554931571856,1.058987402257529,1.1034296234289172,4.552178889851971,-0.02198676428679048,1.1692778855749448,-0.5021341373910327,0.588482059091134 3367 Chemical homeostasis 41 164 2.543610214351615 0.0109713438600544 P09601,P30519,Q658P3,Q99808,Q5BJF2,Q6P4Q7,Q96PU5,P51572,Q96A33,P42785,O15254,P50897,Q15043,P16615,Q15904,Q8N511,Q9Y6C9,P35610,Q8WTV0,P30536,P61916,P02786,Q96TC7,P34913,O15118,Q9Y487,P05067,Q8NE01,Q93050,Q9NQC3,Q12846,P42858,O75503,P53985,Q15067,Q16891,Q9HD20,P04062,O15260,O95202,Q9P035 Processes and pathways GO Biological process msigdb_gobp 0,1,129,259,7,400,268,273,274,21,149,26,293,290,173,48,306,308,60,191,197,200,343,207,85,215,90,351,92,96,345,344,102,103,232,363,115,118,121,123,260 1855,2171,1717,1452,2363,85,149,121,654,2303,593,1015,102,568,3253,393,2548,123,926,891,1170,1456,2101,200,118,3255,1870,610,90,435,1117,1795,1064,1655,1723,1656,0,2374,2180,2881,1942,1118,2928,290,694,2026,808,1181,2655,436,774,2314,2763,3070,2764,612,2317,2431,2603,1,191,2491,207,308,2976,777,2032,21,344,1666,1465,26,1019,1238,273,1605,103,1126,2322,3153,746,197,1808,2261,3158,816,2938,934,1959,1417,3276,2499,2776,345,1815,3352,519,3290,2042,1891,1554,1359,293,232,618,2049,3277,173,2570,2677,363,7,129,598,400,1029,2512,1758,534,2211,1692,48,351,1493,868,1367,60,1090,489,92,274,1318,2143,2739,268,1094,837,343,3280,259,1376,1378,1839,762,1512,2741,1442,115,96,2079,2225,260,711,2162,585,1579,2229,1581,2703,215,734,567,2536,306 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3367 Abnormality of the tongue 30 100 2.5418614027610755 0.0110263887147556 O43933,Q01082,P83436,Q10713,Q96A33,Q7LGA3,P48651,Q71SY5,O95831,Q8NCM8,P10253,Q96RL7,P16278,P01889,P04066,Q9UBM7,O75381,P42356,Q03252,P56589,Q9Y4P3,Q13510,P98175,Q6NUK1,O60826,O75431,P20700,O00754,Q2M1P5,O75844 Drugs and Diseases Human Phenotype Ontology msigdb_hp 132,518,517,398,274,152,533,33,35,537,163,297,41,302,184,325,319,571,328,449,205,78,451,599,593,97,359,480,253,127 1854,735,2707,480,962,1114,2751,3065,2540,132,593,1789,319,97,1395,127,2023,1794,35,302,805,184,1283,1064,2105,163,2599,41,359,1537,3012,2430,2656,2431,1661,1799,571,1349,3124,533,743,660,1238,2818,449,781,1739,1412,517,451,518,1960,328,1417,2396,398,2611,2776,1194,78,903,1817,1426,1307,2946,253,2136,1137,599,33,152,537,1910,672,274,1318,297,628,1506,1097,952,2220,954,955,2741,1993,956,2464,1515,2000,879,3083,325,2227,958,205,2090,2967,712,1274 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3367 Calcium ion binding 27 83 2.538529102306509 0.0111319544013905 O75746,Q9UM22,P80303,Q9BRK5,Q96A33,Q9UJS0,Q14257,Q8IYU8,P19022,O43707,Q9Y4G8,Q13813,P16615,Q03001,Q02818,P27824,P15289,Q9Y680,Q8WVQ1,O75071,O43852,P12814,Q6NUK1,O94813,Q9UPN3,O60476,O95202 Functions GO Molecular function msigdb_gomf 381,14,15,148,274,546,151,534,286,410,564,292,290,423,46,556,555,178,457,68,196,448,599,594,494,235,123 589,800,738,410,196,235,68,2544,2098,381,594,123,2484,1283,2485,2370,2549,1655,2653,448,1942,2838,972,1118,555,1875,290,1346,286,1181,929,2601,2764,556,3150,2491,2887,810,778,779,976,2897,850,1296,15,46,423,1476,2499,1744,292,858,1478,151,2945,1361,1898,599,3101,2737,2573,2056,534,1367,2408,457,274,916,3078,1373,2692,1376,148,2693,649,881,2469,2162,546,14,494,564,178 0.5134346459158582,0.30691434248850596,0.3594471701790773,0.7826588994764823,1.605007630123358,1.3820450016487578,2.975802844788199,-0.5339391468977894,-0.31594654169938047,0.8533559354124849,0.5134346459158582,2.19713106377011,-0.5021341373910327,0.034544176031171075,-0.5021341373910327,-0.43919996831517205,-0.5339391468977894,-0.1372495529245524,-0.5982416058990344,0.7108269558541094,-0.25557908848123395,-0.7297139540963061,0.1999552233330087,0.11801732694304702,0.5636060512556167,-0.22570012371921228,1.1034296234289172,0.0063684354015670136,1.1254866370979533,0.09036639678564706,0.22693649856222178,-0.5659738392609449,-0.6634903102109926,0.5636060512556167,-1.0406246148817728,-0.5021341373910327,-0.7632007073119792,0.30691434248850596,0.3332580754721944,0.3332580754721944,0.1999552233330087,-0.7632007073119792,0.2804141068248859,0.034544176031171075,4.164124775027304,3.286174597616811,0.7588428378146155,-0.05052375805598644,-0.5021341373910327,-0.16653801380920247,1.1034296234289172,0.2804141068248859,-0.05052375805598644,1.9840930614703445,-0.7969425638483784,0.0063684354015670136,-0.22570012371921228,0.5134346459158582,-0.969620885690122,-0.6307459142786708,-0.5339391468977894,-0.28566029525923553,0.588482059091134,0.0063684354015670136,-0.43919996831517205,0.7108269558541094,1.1692778855749448,0.2537554699892711,-0.9345419567612725,0.0063684354015670136,-0.5982416058990344,0.0063684354015670136,2.002235460610414,-0.5982416058990344,0.46269330605308917,0.2804141068248859,-0.4705554931571856,-0.31594654169938047,0.588482059091134,4.1865682400285555,0.6622900003005412,0.5636060512556167,1.722120594018782 3367 Mitochondrial calcium ion transport 7 16 2.5377845034179582 0.011155665292045 Q8IYU8,Q10713,P21796,P45880,Q9Y277,O95202,Q96TA2 Processes and pathways Reactome Pathways msigdb_reactome 534,398,13,19,548,123,648 2595,123,13,2031,19,398,534,1493,1090,1436,648,1507,1376,1579,548,734 -0.5659738392609449,2.19713106377011,4.220028343416946,-0.28566029525923553,3.9215673900004977,0.8299141117114622,0.588482059091134,-0.05052375805598644,0.14549770029311399,-0.02198676428679048,0.46269330605308917,-0.05052375805598644,0.0063684354015670136,-0.07924492702588042,0.588482059091134,0.3854834577363446 3367 Osteopenia 15 69 2.53621492736332 0.0112057936191924 O75431,P07602,Q14108,Q32P28,Q9Y4P3,O75844,Q9NZC9,O75718,Q9NZJ7,Q9NSD9,Q9Y487,P04062,Q96L58,Q9H490,Q13126 Drugs and Diseases Human Phenotype Ontology msigdb_hp 97,65,5,140,205,127,444,206,276,474,215,118,378,289,95 2425,1854,2093,480,2363,1276,771,2711,2540,1526,97,1863,206,127,805,118,3087,1117,1345,65,1176,2838,1286,975,2248,2718,1661,1601,777,2032,2321,1292,1470,1953,614,2194,781,3018,1412,3098,854,1192,696,95,5,1426,1556,140,1311,1428,1620,1824,1763,1983,1092,916,871,378,1571,289,474,1154,444,276,958,2233,215,205,3187 -0.4705554931571856,-0.22570012371921228,-0.31594654169938047,0.6622900003005412,-0.43919996831517205,0.034544176031171075,0.3332580754721944,-0.6307459142786708,-0.5339391468977894,-0.07924492702588042,2.4171181472402936,-0.22570012371921228,1.5652826911718993,2.16231565108635,0.30691434248850596,2.248856101291637,-0.969620885690122,0.11801732694304702,0.0063684354015670136,3.0911332595741183,0.09036639678564706,-0.7297139540963061,0.034544176031171075,0.1999552233330087,-0.37714563952921315,-0.6307459142786708,-0.1372495529245524,-0.10815269963874782,0.3332580754721944,-0.28566029525923553,-0.40806438662984673,0.034544176031171075,-0.05052375805598644,-0.25557908848123395,0.488136037900703,-0.34644068419145774,0.3332580754721944,-0.8652075817496219,-0.02198676428679048,-0.969620885690122,0.2804141068248859,0.09036639678564706,0.41136873678446767,2.4663995632740083,4.744465578955981,-0.02198676428679048,-0.07924492702588042,2.0383028111640002,0.034544176031171075,-0.02198676428679048,-0.10815269963874782,-0.19602066046695343,-0.16653801380920247,-0.25557908848123395,0.14549770029311399,0.2537554699892711,0.2804141068248859,0.8766756507402944,-0.07924492702588042,1.1254866370979533,0.6866243286062695,0.11801732694304702,0.7348993205919421,1.1692778855749448,0.22693649856222178,-0.34644068419145774,1.525203768425511,1.5851890116525102,-1.0765587039609845 3367 Iron ion homeostasis 7 18 2.5348738751256192 0.0112487818418134 P09601,Q658P3,P30519,P02786,Q15904,Q8N511,Q9Y487 Processes and pathways GO Biological process msigdb_gobp 0,129,1,200,173,48,215 1015,3253,200,3255,0,774,1,2491,2976,746,3290,2042,293,173,129,48,1512,215 0.17280963840827135,-1.2607479309781038,1.5851890116525102,-1.2607479309781038,5.77073025593568,0.3332580754721944,5.215090048676801,-0.5021341373910327,-0.8309434988946349,0.3594471701790773,-1.4138401674883982,-0.28566029525923553,1.1034296234289172,1.722120594018782,2.16231565108635,3.286174597616811,-0.05052375805598644,1.525203768425511 3367 Exopeptidase activity 10 31 2.5323153488786776 0.0113312033136374 P10619,Q9HB40,O14773,Q9NZ08,Q9UIQ6,P55786,P42785,O75976,Q9H3G5,O75844 Functions GO Molecular function msigdb_gomf 190,34,70,168,105,84,21,183,27,127 70,127,183,200,655,190,3214,2765,2603,2187,21,3315,1125,84,3351,452,3130,2825,322,1566,3106,1437,2692,27,2150,34,2864,3111,2080,168,105 2.9465065973455364,2.16231565108635,1.6639450277501382,1.5851890116525102,0.4371047742428398,1.6247393272059847,-1.1493154316371736,-0.6634903102109926,-0.5659738392609449,-0.34644068419145774,3.8498324746709085,-1.5322507832020744,0.11801732694304702,2.7513259355917703,-1.907862431915821,0.7108269558541094,-1.004980242603473,-0.6964784202356398,1.014100175743301,-0.07924492702588042,-0.969620885690122,-0.02198676428679048,-0.5982416058990344,3.6904275097045454,-0.31594654169938047,3.525248122809391,-0.7297139540963061,-0.969620885690122,-0.28566029525923553,1.7795540517583925,2.36729383704207 3367 Basolateral plasma membrane 13 38 2.5177710402462483 0.01181000643789 Q12846,Q99808,O75955,P35613,P53985,Q15043,Q6P4Q7,P02786,Q14254,O14936,P30825,P41440,P19022 Localization GO Cellular component msigdb_gocc 345,259,162,165,103,293,400,200,338,277,89,186,286 1855,277,162,1229,200,2484,610,2370,807,1065,692,1658,2109,973,3355,286,436,611,89,742,165,186,103,1126,2322,1735,819,1476,345,1815,858,1965,338,293,400,1037,2690,259 -0.22570012371921228,1.1474357022138544,1.8550102756937976,0.06254274771127205,1.5851890116525102,-0.5021341373910327,0.488136037900703,-0.43919996831517205,0.30691434248850596,0.14549770029311399,0.41136873678446767,-0.1372495529245524,-0.31594654169938047,0.1999552233330087,-1.9957969029261853,1.1254866370979533,0.7348993205919421,0.488136037900703,2.6583280208911844,0.3594471701790773,1.7985369233817154,1.6639450277501382,2.40057096317167,0.11801732694304702,-0.40806438662984673,-0.16653801380920247,0.30691434248850596,-0.05052375805598644,0.9459148854023514,-0.19602066046695343,0.2804141068248859,-0.25557908848123395,0.9687588066338071,1.1034296234289172,0.8299141117114622,0.17280963840827135,-0.5982416058990344,1.2555985905367433 3367 Protease 14 87 2.515186548543569 0.0118969415066938 P10619,Q9HB40,O14773,Q9UIQ6,Q9NZ08,P42892,P28072,P55786,P42785,O75976,P28074,Q9H3G5,P67812,O75844 Functions Protein Atlas Molecular function protein_atlas_molecular_function 190,34,70,105,168,43,170,84,21,183,119,27,93,127 2092,2094,70,550,2595,127,183,967,804,2549,655,190,3214,2109,1346,170,119,2765,2603,849,2434,2891,21,43,2721,3221,3315,2607,1188,1070,1125,2935,84,899,93,1958,2441,2198,452,2849,1025,2335,439,347,375,1689,2135,1136,1031,3104,3130,1625,2408,202,1497,724,1983,1984,3297,365,458,1437,1322,648,1772,3280,507,708,27,2150,681,1042,34,2864,3111,493,2080,168,1642,1334,105,607,732,1339,2089,734,2917 -0.31594654169938047,-0.31594654169938047,2.9465065973455364,0.5636060512556167,-0.5659738392609449,2.16231565108635,1.6639450277501382,0.1999552233330087,0.30691434248850596,-0.5339391468977894,0.4371047742428398,1.6247393272059847,-1.1493154316371736,-0.31594654169938047,0.0063684354015670136,1.7413465847323417,2.2316801472635333,-0.6634903102109926,-0.5659738392609449,0.2804141068248859,-0.4705554931571856,-0.7632007073119792,3.8498324746709085,3.34039786005235,-0.6307459142786708,-1.1493154316371736,-1.5322507832020744,-0.5659738392609449,0.09036639678564706,0.14549770029311399,0.11801732694304702,-0.7969425638483784,2.7513259355917703,0.2537554699892711,2.5151499572076714,-0.25557908848123395,-0.4705554931571856,-0.34644068419145774,0.7108269558541094,-0.7297139540963061,0.17280963840827135,-0.40806438662984673,0.7348993205919421,0.9459148854023514,0.8766756507402944,-0.1372495529245524,-0.31594654169938047,0.11801732694304702,0.17280963840827135,-0.969620885690122,-1.004980242603473,-0.10815269963874782,-0.43919996831517205,1.5851890116525102,-0.05052375805598644,0.3854834577363446,-0.25557908848123395,-0.25557908848123395,-1.45295805178107,0.8998745416649946,0.7108269558541094,-0.02198676428679048,0.034544176031171075,0.46269330605308917,-0.16653801380920247,-1.3366301135330916,0.6378225083090472,0.41136873678446767,3.6904275097045454,-0.31594654169938047,0.4371047742428398,0.17280963840827135,3.525248122809391,-0.7297139540963061,-0.969620885690122,0.6622900003005412,-0.28566029525923553,1.7795540517583925,-0.10815269963874782,0.034544176031171075,2.36729383704207,0.5134346459158582,0.3854834577363446,0.034544176031171075,-0.28566029525923553,0.3854834577363446,-0.7632007073119792 3367 Cellular monovalent inorganic cation homeostasis 10 23 2.513097670259291 0.0119676196823925 O75503,Q92544,Q96PU5,Q15904,Q8N511,Q9Y487,P06576,P50897,Q93050,Q9UI12 Processes and pathways GO Biological process msigdb_gobp 102,489,268,173,48,215,435,26,92,585 102,891,610,435,2180,2763,2431,26,1019,1126,2322,746,1417,173,48,489,92,1318,268,2162,585,215,2536 2.40057096317167,0.2537554699892711,0.488136037900703,0.7348993205919421,-0.34644068419145774,-0.6634903102109926,-0.4705554931571856,3.6904275097045454,0.17280963840827135,0.11801732694304702,-0.40806438662984673,0.3594471701790773,-0.02198676428679048,1.722120594018782,3.286174597616811,0.6622900003005412,2.5793442451134623,0.034544176031171075,1.2126457954814382,-0.31594654169938047,0.5385907773537494,1.525203768425511,-0.5021341373910327 3367 Apical plasma membrane 17 39 2.5105549972744874 0.0120541543811298 P30825,Q99808,O75955,P35241,Q9Y4G8,P53985,Q15043,Q14254,P08183,Q13131,P05023,P26038,Q16625,P20020,Q86UE4,P41440,P19022 Localization GO Cellular component msigdb_gocc 89,259,162,657,564,103,293,338,110,519,610,611,242,436,153,186,286 1855,2363,1391,162,2480,2484,610,110,807,1723,1065,692,3011,973,286,436,1537,611,89,657,1539,2187,2976,186,103,1126,2322,746,519,2943,338,293,1309,242,153,259,1218,1268,564 -0.22570012371921228,-0.43919996831517205,-0.02198676428679048,1.8550102756937976,-0.5021341373910327,-0.5021341373910327,0.488136037900703,2.2999956417932186,0.30691434248850596,-0.16653801380920247,0.14549770029311399,0.41136873678446767,-0.8652075817496219,0.1999552233330087,1.1254866370979533,0.7348993205919421,-0.07924492702588042,0.488136037900703,2.6583280208911844,0.4371047742428398,-0.07924492702588042,-0.34644068419145774,-0.8309434988946349,1.6639450277501382,2.40057096317167,0.11801732694304702,-0.40806438662984673,0.3594471701790773,0.6132203653820887,-0.7969425638483784,0.9687588066338071,1.1034296234289172,0.034544176031171075,1.3402905479186136,1.9840930614703445,1.2555985905367433,0.09036639678564706,0.06254274771127205,0.5636060512556167 3367 Amide binding 17 104 2.507936278050121 0.0121438564611309 P24390,P07602,Q9H7Z7,O14773,Q9UIQ6,Q9NZ08,P42892,Q15392,P21796,Q9UM22,O00264,Q99735,Q9Y680,P45880,P55786,P55899,Q8WTV0 Functions GO Molecular function msigdb_gomf 2,65,67,70,105,168,43,76,13,14,106,147,178,19,84,180,60 2537,1340,106,370,888,3318,70,1588,3271,1279,1936,3314,2649,2971,302,333,806,3341,65,1065,554,1594,481,3335,2109,3302,13,2929,3036,2,2029,2764,612,3091,1598,639,308,716,2931,2116,186,43,3246,19,1883,743,1466,2190,812,2978,1020,2557,1070,84,180,2194,852,2195,3158,1956,1547,1741,2264,1355,3099,1476,2499,2670,3200,1081,2199,2042,2046,1424,76,2343,469,60,2411,405,916,2065,835,3350,1263,1507,147,2415,708,762,917,67,763,631,168,276,1106,2228,105,14,2964,2012,2967,178 -0.5339391468977894,0.0063684354015670136,2.333769977004763,0.8766756507402944,0.2537554699892711,-1.5724386516725661,2.9465065973455364,-0.10815269963874782,-1.3366301135330916,0.034544176031171075,-0.25557908848123395,-1.5322507832020744,-0.5982416058990344,-0.8309434988946349,1.081263578277897,0.9687588066338071,0.30691434248850596,-1.736960805865547,3.0911332595741183,0.14549770029311399,0.5636060512556167,-0.10815269963874782,0.6622900003005412,-1.6539313317624937,-0.31594654169938047,-1.4924261166507573,4.220028343416946,-0.7969425638483784,-0.8997389788237078,5.106453588871854,-0.28566029525923553,-0.6634903102109926,0.488136037900703,-0.969620885690122,-0.10815269963874782,0.46269330605308917,1.058987402257529,0.3854834577363446,-0.7969425638483784,-0.31594654169938047,1.6639450277501382,3.34039786005235,-1.2232904675772427,3.9215673900004977,-0.22570012371921228,0.3594471701790773,-0.05052375805598644,-0.34644068419145774,0.30691434248850596,-0.8309434988946349,0.17280963840827135,-0.5339391468977894,0.14549770029311399,2.7513259355917703,1.7028121530513547,-0.34644068419145774,0.2804141068248859,-0.34644068419145774,-1.0406246148817728,-0.25557908848123395,-0.07924492702588042,-0.16653801380920247,-0.37714563952921315,0.0063684354015670136,-0.969620885690122,-0.05052375805598644,-0.5021341373910327,-0.5982416058990344,-1.112787329154505,0.14549770029311399,-0.34644068419145774,-0.28566029525923553,-0.28566029525923553,-0.02198676428679048,2.8873405559171093,-0.40806438662984673,0.6866243286062695,3.1896999455248927,-0.43919996831517205,0.8063488749900722,0.2537554699892711,-0.28566029525923553,0.30691434248850596,-1.8645172986247718,0.06254274771127205,-0.05052375805598644,2.002235460610414,-0.43919996831517205,0.41136873678446767,0.3594471701790773,0.2537554699892711,3.062574077848557,0.3594471701790773,0.488136037900703,1.7795540517583925,1.1692778855749448,0.14549770029311399,-0.34644068419145774,2.36729383704207,4.1865682400285555,-0.7969425638483784,-0.25557908848123395,-0.7969425638483784,1.722120594018782 3367 Behavior 24 76 2.5053831524981685 0.0122318806994914 O76024,Q8N2K0,P50897,P10253,Q96RL7,P17900,P30536,P54802,O15118,Q14203,P80404,P05067,Q13641,P42858,Q92542,P53985,P50416,O00264,Q15154,Q99538,P04062,Q7Z406,P42345,O75844 Processes and pathways GO Biological process msigdb_gobp 393,419,26,163,297,169,191,83,85,468,211,90,346,344,227,103,485,106,362,507,118,503,498,127 2299,106,1391,85,2173,3006,127,1168,393,2548,2927,118,3283,3255,928,90,1531,2714,1795,1064,2652,2245,163,1346,169,2811,2249,2431,191,2252,3177,777,498,2434,344,1879,1949,485,26,2037,103,83,2391,2263,211,1191,1417,519,1241,2042,346,468,362,3277,1753,2735,503,1489,419,1694,227,2458,2526,1209,297,1833,3280,507,762,2291,1995,730,2352,2355,2084,2091 -0.40806438662984673,2.333769977004763,-0.02198676428679048,2.7359582136753127,-0.34644068419145774,-0.8652075817496219,2.16231565108635,0.09036639678564706,0.8299141117114622,-0.5339391468977894,-0.7969425638483784,2.248856101291637,-1.37506621536203,-1.2607479309781038,0.22693649856222178,2.595251590463738,-0.07924492702588042,-0.6307459142786708,-0.19602066046695343,0.14549770029311399,-0.5982416058990344,-0.37714563952921315,1.8362643641609107,0.0063684354015670136,1.7413465847323417,-0.6964784202356398,-0.37714563952921315,-0.4705554931571856,1.6247393272059847,-0.37714563952921315,-1.0765587039609845,0.3332580754721944,0.6378225083090472,-0.4705554931571856,0.9459148854023514,-0.22570012371921228,-0.25557908848123395,0.6622900003005412,3.6904275097045454,-0.28566029525923553,2.40057096317167,2.7513259355917703,-0.43919996831517205,-0.37714563952921315,1.525203768425511,0.09036639678564706,-0.02198676428679048,0.6132203653820887,0.06254274771127205,-0.28566029525923553,0.9459148854023514,0.6866243286062695,0.8998745416649946,-1.3366301135330916,-0.16653801380920247,-0.6307459142786708,0.6378225083090472,-0.05052375805598644,0.7826588994764823,-0.1372495529245524,1.443957948969997,-0.4705554931571856,-0.5021341373910327,0.09036639678564706,1.1034296234289172,-0.19602066046695343,-1.3366301135330916,0.6378225083090472,0.3594471701790773,-0.37714563952921315,-0.25557908848123395,0.3854834577363446,-0.40806438662984673,-0.40806438662984673,-0.28566029525923553,-0.28566029525923553 3367 Ichthyosis 11 36 2.503322654726539 0.0123033323294245 P48449,O43933,Q15800,O75381,Q15125,Q14691,P04062,O95721,P51648,O95470,P50402 Drugs and Diseases Human Phenotype Ontology msigdb_hp 98,132,69,319,166,111,118,247,88,250,193 2711,132,319,250,247,805,118,3355,1286,975,2248,2889,98,193,88,449,2194,3223,1743,1554,111,166,1247,69,1311,1822,1824,2785,1763,331,581,1571,1921,2585,2233,3187 -0.6307459142786708,2.12722970929693,1.014100175743301,1.276921824455599,1.2981442560194676,0.30691434248850596,2.248856101291637,-1.9957969029261853,0.034544176031171075,0.1999552233330087,-0.37714563952921315,-0.7632007073119792,2.4171181472402936,1.6247393272059847,2.6739608306410108,0.7108269558541094,-0.34644068419145774,-1.1493154316371736,-0.16653801380920247,-0.07924492702588042,2.2999956417932186,1.7985369233817154,0.06254274771127205,2.9611783576004687,0.034544176031171075,-0.19602066046695343,-0.19602066046695343,-0.6634903102109926,-0.16653801380920247,0.9914868411153721,0.5385907773537494,-0.07924492702588042,-0.22570012371921228,-0.5339391468977894,-0.34644068419145774,-1.0765587039609845 3367