term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Protease 21 87 3.591000807444033 0.0003294106154196 Q4J6C6,Q9NUQ7,P42785,Q9UPU5,Q9UIQ6,Q9BYT8,Q9HB40,P55786,P28074,Q9NZ08,P48147,Q2T9J0,P28072,P10619,Q16740,P42892,O75844,Q8TCT9,Q96K76,P67812,P83111 Functions Protein Atlas Molecular function protein_atlas_molecular_function 245,130,3,16,19,154,28,159,35,47,170,49,52,61,62,63,87,235,254,241,243 1731,2437,319,1202,1206,87,644,383,888,1476,2917,61,1224,728,818,52,35,2778,2328,733,2335,737,3,63,2599,170,3226,740,594,1365,328,1782,159,596,241,2927,243,3332,2619,2228,1387,62,49,245,402,1664,1154,1535,287,2511,2812,1405,679,235,1548,687,952,2252,851,2993,254,959,1690,961,2824,2951,1177,154,785,2411,786,1299,28,1186,2414,130,701,47,3145,3312,19,457,16,3250,514,3012,2755 -0.09094104587744528,-0.3380597911426015,0.6987063152944422,0.10157608769830284,0.10157608769830284,1.7052535001830216,0.38234507015049096,0.6094870655900769,0.24312104666747653,0.005872513874080369,-0.5928502525010018,2.283114015588119,0.10157608769830284,0.3361888423900969,0.2897820267826493,2.431534530000306,3.0039248680970876,-0.4899972174116964,-0.28803660939734893,0.3361888423900969,-0.28803660939734893,0.3361888423900969,7.767211111294991,2.132393733047149,-0.388392317630512,1.1317712009042973,-1.1255266262233685,0.3361888423900969,0.4282542060735226,0.053860976884978005,0.6987063152944422,-0.09094104587744528,1.2159277397438069,0.4282542060735226,0.8744716799879915,-0.5928502525010018,0.8744716799879915,-2.0992610771115365,-0.388392317630512,-0.23831786606746352,0.053860976884978005,2.245653162379946,2.5413946027810876,0.8744716799879915,0.6094870655900769,-0.04239342030431858,0.14902186735214557,0.005872513874080369,0.7870267798407822,-0.3380597911426015,-0.4899972174116964,0.053860976884978005,0.38234507015049096,0.9178727874245445,0.005872513874080369,0.38234507015049096,0.24312104666747653,-0.23831786606746352,0.2897820267826493,-0.6447419635510961,0.8744716799879915,0.24312104666747653,-0.04239342030431858,0.24312104666747653,-0.4899972174116964,-0.5928502525010018,0.14902186735214557,1.257715066848026,0.3361888423900969,-0.28803660939734893,0.3361888423900969,0.10157608769830284,3.4129471399409548,0.14902186735214557,-0.28803660939734893,1.381940746478781,0.38234507015049096,2.5777445433602932,-0.8553842121388305,-1.6881333429715428,4.4014392320994515,0.5645328647779381,5.023653846020728,-1.1804567452748522,0.5193447980380466,-0.6447419635510961,-0.43903817143719953 3367 Endopeptidase activity 22 64 3.300722739334532 0.0009643613152663 P60900,Q4J6C6,P49721,Q9UPU5,Q70CQ2,Q9BYT8,P28074,P48147,Q9NZ08,Q2T9J0,P28072,Q6NTF9,Q16740,P42892,P20618,P53634,O75844,O14773,Q8TCT9,P49720,Q96K76,P67812 Functions GO Molecular function msigdb_gomf 128,245,10,16,287,154,35,170,47,49,52,302,62,63,192,328,87,319,235,354,254,241 319,1202,1206,87,2848,1476,1761,728,818,192,1345,1895,647,52,35,2328,2329,733,2335,737,63,2599,170,354,10,740,594,328,1782,128,241,665,1518,2619,2228,62,49,245,402,1664,302,287,1405,679,235,683,1548,687,952,2252,254,1690,961,2824,1177,2117,154,47,3145,3312,16,3250,514,3012 0.6987063152944422,0.10157608769830284,0.10157608769830284,1.7052535001830216,-0.5412682933157936,0.005872513874080369,-0.09094104587744528,0.3361888423900969,0.2897820267826493,1.046822951105993,0.053860976884978005,-0.13977468780074367,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.28803660939734893,-0.28803660939734893,0.3361888423900969,-0.28803660939734893,0.3361888423900969,2.132393733047149,-0.388392317630512,1.1317712009042973,0.6542105287099975,6.0439644005275905,0.3361888423900969,0.4282542060735226,0.6987063152944422,-0.09094104587744528,1.381940746478781,0.8744716799879915,0.38234507015049096,0.005872513874080369,-0.388392317630512,-0.23831786606746352,2.245653162379946,2.5413946027810876,0.8744716799879915,0.6094870655900769,-0.04239342030431858,0.7429774213920438,0.7870267798407822,0.053860976884978005,0.38234507015049096,0.9178727874245445,0.38234507015049096,0.005872513874080369,0.38234507015049096,0.24312104666747653,-0.23831786606746352,0.8744716799879915,-0.04239342030431858,0.24312104666747653,-0.4899972174116964,0.14902186735214557,-0.18889877938207092,1.257715066848026,2.5777445433602932,-0.8553842121388305,-1.6881333429715428,5.023653846020728,-1.1804567452748522,0.5193447980380466,-0.6447419635510961 3367 Intrinsic component of organelle membrane 47 111 3.261980667984972 0.0011063668830664 Q9NQC3,Q9UH99,Q9BWH2,Q9NX63,Q9BTV4,Q9HC21,O60830,Q99595,Q14739,Q13505,P51572,Q9Y2R0,P13473,Q9Y282,O95470,Q9H490,O43752,Q9UG56,P20339,Q96S52,P56589,Q9UBM7,O14925,Q5XKP0,Q6NTF9,Q9BUR5,P42892,Q86Y82,P04439,O95070,Q969N2,O43505,Q9NRK6,Q15125,Q15629,Q9BUN8,O75844,Q8TB61,Q6ZRP7,Q8TCT9,Q10471,Q6UXV4,Q00325,Q15070,Q5J8M3,O15118,P01889 Localization GO Cellular component msigdb_gocc 129,131,559,274,412,413,12,18,151,26,393,157,389,31,34,313,516,316,522,175,530,54,420,194,302,198,63,196,424,423,623,70,207,74,333,80,87,367,365,235,231,364,478,483,401,125,126 1868,2842,2296,420,3096,125,1324,2969,70,516,722,3351,12,3100,87,884,813,1097,1743,423,34,1880,727,126,424,1601,2585,389,2588,522,1349,1350,2329,2595,63,828,1014,393,530,913,1249,478,231,925,26,750,151,1261,753,483,74,1262,333,1809,2370,1812,401,2717,194,302,364,365,1404,1947,196,2814,2815,942,1162,2518,1952,367,235,1048,1548,623,1411,175,1058,18,3353,1697,412,80,198,559,630,313,1438,1439,413,1068,129,207,1993,274,1300,794,1302,1997,54,316,975,131,31,157,2429,2666,3012,801,871 -0.13977468780074367,-0.5412682933157936,-0.28803660939734893,0.5645328647779381,-0.8022645150247569,1.381940746478781,0.053860976884978005,-0.6447419635510961,2.0177872441211355,0.4739196680085796,0.3361888423900969,-2.962986316850552,5.531143228715627,-0.8022645150247569,1.7052535001830216,0.24312104666747653,0.2897820267826493,0.14902186735214557,-0.09094104587744528,0.5645328647779381,3.0039248680970876,-0.13977468780074367,0.3361888423900969,1.381940746478781,0.5645328647779381,-0.04239342030431858,-0.388392317630512,0.6094870655900769,-0.388392317630512,0.4739196680085796,0.053860976884978005,0.053860976884978005,-0.28803660939734893,-0.388392317630512,2.132393733047149,0.2897820267826493,0.19620224214011292,0.6094870655900769,0.4739196680085796,0.24312104666747653,0.10157608769830284,0.5193447980380466,0.9178727874245445,0.24312104666747653,3.578720683939666,0.3361888423900969,1.257715066848026,0.10157608769830284,0.3361888423900969,0.5193447980380466,1.9792784396533925,0.10157608769830284,0.6987063152944422,-0.09094104587744528,-0.28803660939734893,-0.09094104587744528,0.6094870655900769,-0.43903817143719953,1.046822951105993,0.7429774213920438,0.6542105287099975,0.6542105287099975,0.053860976884978005,-0.13977468780074367,1.046822951105993,-0.4899972174116964,-0.4899972174116964,0.24312104666747653,0.14902186735214557,-0.3380597911426015,-0.13977468780074367,0.6542105287099975,0.9178727874245445,0.19620224214011292,0.005872513874080369,0.4282542060735226,0.053860976884978005,1.1317712009042973,0.19620224214011292,4.731666431481315,-3.5466505530698798,-0.04239342030431858,0.6094870655900769,1.8628092769514064,1.046822951105993,0.4739196680085796,0.4282542060735226,0.7429774213920438,0.053860976884978005,0.053860976884978005,0.6094870655900769,0.19620224214011292,1.381940746478781,1.004045806677848,-0.13977468780074367,0.8308572620954069,0.10157608769830284,0.3361888423900969,0.10157608769830284,-0.13977468780074367,2.431534530000306,0.7429774213920438,0.24312104666747653,1.381940746478781,3.2104683932450104,1.257715066848026,-0.28803660939734893,-0.388392317630512,-0.6447419635510961,0.3361888423900969,0.2897820267826493 3367 Receptor 8 28 3.213501425259138 0.0013112714722305 Q9UQB8,Q9NR77,Q14108,A6NIH7,Q14118,Q9BUN8,P20645,Q8WTV0 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 0,67,164,9,263,80,23,25 9,1582,2969,876,882,886,1213,1751,1759,23,2334,2798,164,263,1806,2626,302,2243,1666,25,1957,80,970,1989,67,2835,2144,0 6.382598192426078,-0.04239342030431858,-0.6447419635510961,0.24312104666747653,0.24312104666747653,0.24312104666747653,0.10157608769830284,-0.09094104587744528,-0.09094104587744528,4.123694916854529,-0.28803660939734893,-0.4899972174116964,1.1739472326847418,0.8308572620954069,-0.09094104587744528,-0.388392317630512,0.7429774213920438,-0.23831786606746352,-0.04239342030431858,3.6115632124813404,-0.13977468780074367,1.8628092769514064,0.24312104666747653,-0.13977468780074367,2.0561416638490693,-0.4899972174116964,-0.18889877938207092,9.674117275578304 3367 Outer membrane 30 83 3.211533226633951 0.0013202870177471 Q9BWH2,Q9NX63,Q9NQZ5,Q5VT66,Q13505,Q9NVH0,Q99720,Q9NZJ7,Q9NVT9,Q9NS69,O43169,Q9UBM7,P45880,Q6SZW1,Q5XKP0,P09601,Q9BUR5,Q9BVC6,Q9NX47,O75323,Q96TC7,Q9BXR0,P50402,Q96RL7,P21796,Q8N2A8,Q86UT6,Q6UXV4,P30536,Q9NWX6 Localization GO Cellular component msigdb_gocc 559,274,415,152,26,449,43,315,450,46,292,54,56,437,194,60,198,65,345,321,89,501,214,216,100,101,486,364,113,116 1459,1320,2439,292,989,1588,321,3100,1097,887,727,1595,2578,1599,60,2853,100,113,2188,2595,826,1005,56,214,828,1627,2347,3179,1646,26,2230,1390,2370,1812,152,194,1041,437,364,1399,2382,486,2815,942,1162,541,101,1277,1278,1827,1168,774,950,1418,216,89,962,1838,43,2895,198,65,559,560,501,3221,3118,415,46,449,1993,450,116,345,274,793,315,54,975,980,3347,801,2012 0.005872513874080369,0.053860976884978005,-0.3380597911426015,0.7429774213920438,0.19620224214011292,-0.04239342030431858,0.6987063152944422,-0.8022645150247569,0.14902186735214557,0.24312104666747653,0.3361888423900969,-0.04239342030431858,-0.388392317630512,-0.04239342030431858,2.283114015588119,-0.5412682933157936,1.6254733747117993,1.463832977402664,-0.23831786606746352,-0.388392317630512,0.2897820267826493,0.19620224214011292,2.394640025697565,0.961063282020524,0.2897820267826493,-0.04239342030431858,-0.28803660939734893,-0.9625354940644615,-0.04239342030431858,3.578720683939666,-0.23831786606746352,0.053860976884978005,-0.28803660939734893,-0.09094104587744528,1.257715066848026,1.046822951105993,0.19620224214011292,0.5645328647779381,0.6542105287099975,0.053860976884978005,-0.28803660939734893,0.5193447980380466,-0.4899972174116964,0.24312104666747653,0.14902186735214557,0.4739196680085796,1.6254733747117993,0.10157608769830284,0.10157608769830284,-0.09094104587744528,0.14902186735214557,0.3361888423900969,0.24312104666747653,0.053860976884978005,0.961063282020524,1.7052535001830216,0.24312104666747653,-0.09094104587744528,2.8638632384419833,-0.5412682933157936,1.046822951105993,2.0943433015075343,0.4739196680085796,0.4739196680085796,0.5193447980380466,-1.070895711677453,-0.8022645150247569,0.6094870655900769,2.7575257190991964,0.5645328647779381,-0.13977468780074367,0.5645328647779381,1.463832977402664,0.6987063152944422,0.8308572620954069,0.3361888423900969,0.7429774213920438,2.431534530000306,0.24312104666747653,0.24312104666747653,-2.710654339272441,0.3361888423900969,-0.13977468780074367 3367 Receptor 13 35 3.083000330864216 0.0020492492711374 P30825,P55899,Q9Y2I1,Q14108,O15173,O15031,Q99720,Q14118,Q9NS69,P20645,Q14739,Q8WTV0,O15118 Functions Protein Atlas Molecular function protein_atlas_molecular_function 212,180,132,164,189,103,43,263,46,23,151,25,125 1459,1580,103,125,189,1472,1751,1475,1754,2580,2035,3025,1759,728,23,3176,212,825,180,3268,834,164,263,151,755,1532,25,953,1838,43,46,132,1078,1729,347 0.005872513874080369,-0.04239342030431858,1.5450050959353323,1.381940746478781,1.046822951105993,0.005872513874080369,-0.09094104587744528,0.005872513874080369,-0.09094104587744528,-0.388392317630512,-0.18889877938207092,-0.6969423099361801,-0.09094104587744528,0.3361888423900969,4.123694916854529,-0.9625354940644615,0.961063282020524,0.2897820267826493,1.0893972532895093,-1.2912106707426125,0.2897820267826493,1.1739472326847418,0.8308572620954069,1.257715066848026,0.3361888423900969,0.005872513874080369,3.6115632124813404,0.24312104666747653,-0.09094104587744528,2.8638632384419833,2.7575257190991964,1.381940746478781,0.19620224214011292,-0.04239342030431858,0.6987063152944422 3367 Peptidase activity 30 118 3.077972325125928 0.002084142691819 P60900,Q4J6C6,Q9NUQ7,P42785,P49721,Q9UPU5,Q9UIQ6,Q70CQ2,Q9BYT8,Q9HB40,P55786,P28074,Q9NZ08,P48147,Q2T9J0,P28072,P10619,Q6NTF9,Q16740,P42892,P20618,P53634,O75844,O14773,Q99496,Q8TCT9,P49720,Q96K76,P67812,P83111 Functions GO Molecular function msigdb_gomf 128,245,130,3,10,16,19,287,154,28,159,35,47,170,49,52,61,302,62,63,192,328,87,319,369,235,354,254,241,243 1731,2437,319,874,1202,1206,87,644,2307,383,888,1472,2848,1476,2917,61,1224,1761,728,818,192,1345,1895,647,52,35,2778,2328,2329,901,733,2335,737,3,63,2599,170,354,10,3226,1244,740,594,1365,328,1782,159,128,596,241,2927,243,3332,665,2707,1518,2619,2228,1387,62,49,245,1659,402,1664,1154,1535,302,1272,287,2511,1819,2812,1405,2991,679,235,683,1548,2393,2394,687,952,2252,624,3202,851,2993,254,959,1690,961,2824,369,2951,1177,2117,695,154,785,2411,786,1299,28,1186,2414,130,701,47,3145,3312,19,457,16,3250,514,3012,2755 -0.09094104587744528,-0.3380597911426015,0.6987063152944422,0.24312104666747653,0.10157608769830284,0.10157608769830284,1.7052535001830216,0.38234507015049096,-0.28803660939734893,0.6094870655900769,0.24312104666747653,0.005872513874080369,-0.5412682933157936,0.005872513874080369,-0.5928502525010018,2.283114015588119,0.10157608769830284,-0.09094104587744528,0.3361888423900969,0.2897820267826493,1.046822951105993,0.053860976884978005,-0.13977468780074367,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.4899972174116964,-0.28803660939734893,-0.28803660939734893,0.24312104666747653,0.3361888423900969,-0.28803660939734893,0.3361888423900969,7.767211111294991,2.132393733047149,-0.388392317630512,1.1317712009042973,0.6542105287099975,6.0439644005275905,-1.1255266262233685,0.10157608769830284,0.3361888423900969,0.4282542060735226,0.053860976884978005,0.6987063152944422,-0.09094104587744528,1.2159277397438069,1.381940746478781,0.4282542060735226,0.8744716799879915,-0.5928502525010018,0.8744716799879915,-2.0992610771115365,0.38234507015049096,-0.43903817143719953,0.005872513874080369,-0.388392317630512,-0.23831786606746352,0.053860976884978005,2.245653162379946,2.5413946027810876,0.8744716799879915,-0.04239342030431858,0.6094870655900769,-0.04239342030431858,0.14902186735214557,0.005872513874080369,0.7429774213920438,0.10157608769830284,0.7870267798407822,-0.3380597911426015,-0.09094104587744528,-0.4899972174116964,0.053860976884978005,-0.6447419635510961,0.38234507015049096,0.9178727874245445,0.38234507015049096,0.005872513874080369,-0.28803660939734893,-0.28803660939734893,0.38234507015049096,0.24312104666747653,-0.23831786606746352,0.4282542060735226,-1.0165649980725264,0.2897820267826493,-0.6447419635510961,0.8744716799879915,0.24312104666747653,-0.04239342030431858,0.24312104666747653,-0.4899972174116964,0.6542105287099975,-0.5928502525010018,0.14902186735214557,-0.18889877938207092,0.38234507015049096,1.257715066848026,0.3361888423900969,-0.28803660939734893,0.3361888423900969,0.10157608769830284,3.4129471399409548,0.14902186735214557,-0.28803660939734893,1.381940746478781,0.38234507015049096,2.5777445433602932,-0.8553842121388305,-1.6881333429715428,4.4014392320994515,0.5645328647779381,5.023653846020728,-1.1804567452748522,0.5193447980380466,-0.6447419635510961,-0.43903817143719953 3367 Regulation of blood pressure 6 17 3.023149083260144 0.0025015897122362 P42785,P80404,Q9NZ08,Q9UIQ6,Q9HB40,P09601 Processes and pathways GO Biological process msigdb_gobp 3,36,47,19,28,60 2447,1101,1597,60,2452,2588,3,63,3033,1624,36,2497,2650,28,47,19,3172 -0.3380597911426015,0.14902186735214557,-0.04239342030431858,2.283114015588119,-0.3380597911426015,-0.388392317630512,7.767211111294991,2.132393733047149,-0.6969423099361801,-0.04239342030431858,2.969090607110795,-0.3380597911426015,-0.388392317630512,3.4129471399409548,2.5777445433602932,4.4014392320994515,-0.908808220790615 3367 Intrinsic component of endoplasmic reticulum membrane 16 48 3.009624305559528 0.0026157101877239 Q9NQC3,O95470,Q9H490,Q8TCT9,Q15125,Q96S52,Q15629,Q9BUN8,Q8TB61,Q9UBM7,Q6NTF9,O75844,Q5J8M3,P51572,P01889,Q9Y282 Localization GO Cellular component msigdb_gocc 129,34,313,235,74,175,333,80,367,54,302,87,401,393,126,31 1868,2296,3096,2969,87,813,34,126,424,1601,1349,1350,2329,393,913,1249,925,750,1261,753,74,333,401,302,1404,1947,2814,2518,367,235,1548,623,1411,175,1058,1697,80,313,1068,129,1300,794,1302,1997,54,31,2666,871 -0.13977468780074367,-0.28803660939734893,-0.8022645150247569,-0.6447419635510961,1.7052535001830216,0.2897820267826493,3.0039248680970876,1.381940746478781,0.5645328647779381,-0.04239342030431858,0.053860976884978005,0.053860976884978005,-0.28803660939734893,0.6094870655900769,0.24312104666747653,0.10157608769830284,0.24312104666747653,0.3361888423900969,0.10157608769830284,0.3361888423900969,1.9792784396533925,0.6987063152944422,0.6094870655900769,0.7429774213920438,0.053860976884978005,-0.13977468780074367,-0.4899972174116964,-0.3380597911426015,0.6542105287099975,0.9178727874245445,0.005872513874080369,0.4282542060735226,0.053860976884978005,1.1317712009042973,0.19620224214011292,-0.04239342030431858,1.8628092769514064,0.7429774213920438,0.19620224214011292,1.381940746478781,0.10157608769830284,0.3361888423900969,0.10157608769830284,-0.13977468780074367,2.431534530000306,3.2104683932450104,-0.388392317630512,0.2897820267826493 3367 Ion transmembrane transporter activity 27 80 3.0058021572154554 0.0026488127947461 P51798,O43772,Q9HC21,Q9C0H2,P11166,O75964,O95202,Q70HW3,P56385,Q9HD20,P45880,P36542,Q02978,P61421,Q9BVC6,Q8TB61,Q6N075,P30825,Q9Y696,P21796,P21283,Q9UI12,P12236,Q9H2D1,Q9UDW1,Q00325,P21281 Functions GO Molecular function msigdb_gomf 475,2,413,145,388,33,519,45,529,51,56,297,533,532,65,367,363,212,237,100,588,372,470,105,118,478,121 2295,2016,1201,2,722,1095,584,33,519,1880,1471,1597,1102,1334,2168,2450,890,1336,2849,2319,388,2585,470,1000,1226,2588,2322,121,588,100,1347,2777,212,1615,297,1905,1492,2978,56,3191,2338,475,1917,911,2208,742,529,532,1249,478,533,3156,2229,1033,755,363,938,1271,1397,45,1952,367,953,3163,1693,65,145,2898,105,3281,1438,413,51,1998,118,372,867,980,2006,237 -0.28803660939734893,-0.18889877938207092,0.10157608769830284,8.462226464311355,0.3361888423900969,0.14902186735214557,0.4282542060735226,3.0386401585275027,0.4739196680085796,-0.13977468780074367,0.005872513874080369,-0.04239342030431858,0.14902186735214557,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,0.24312104666747653,0.053860976884978005,-0.5412682933157936,-0.28803660939734893,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.19620224214011292,0.10157608769830284,-0.388392317630512,-0.28803660939734893,1.422977916752635,0.4282542060735226,1.6254733747117993,0.053860976884978005,-0.4899972174116964,0.961063282020524,-0.04239342030431858,0.7429774213920438,-0.13977468780074367,0.005872513874080369,-0.6447419635510961,2.394640025697565,-1.0165649980725264,-0.28803660939734893,0.5193447980380466,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,0.3361888423900969,0.4739196680085796,0.4739196680085796,0.10157608769830284,0.5193447980380466,0.4739196680085796,-0.908808220790615,-0.23831786606746352,0.19620224214011292,0.3361888423900969,0.6542105287099975,0.24312104666747653,0.10157608769830284,0.053860976884978005,2.7575257190991964,-0.13977468780074367,0.6542105287099975,0.24312104666747653,-0.908808220790615,-0.04239342030431858,2.0943433015075343,1.2993115136492674,-0.5412682933157936,1.5450050959353323,-1.3470325431471153,0.053860976884978005,0.6094870655900769,2.5049104893301823,-0.13977468780074367,1.463832977402664,0.6542105287099975,0.2897820267826493,0.24312104666747653,-0.13977468780074367,0.9178727874245445 3367 Serine hydrolase activity 11 19 2.927868484249136 0.0034129437572008 Q4J6C6,P42785,P48147,Q2T9J0,P53634,O14773,Q6NTF9,P10619,Q9HB40,P67812,Q16740 Functions GO Molecular function msigdb_gomf 245,3,170,49,328,319,302,61,28,241,62 319,644,61,1761,2328,733,3,170,1365,328,241,62,49,245,402,302,2812,785,28 0.6987063152944422,0.38234507015049096,2.283114015588119,-0.09094104587744528,-0.28803660939734893,0.3361888423900969,7.767211111294991,1.1317712009042973,0.053860976884978005,0.6987063152944422,0.8744716799879915,2.245653162379946,2.5413946027810876,0.8744716799879915,0.6094870655900769,0.7429774213920438,-0.4899972174116964,0.3361888423900969,3.4129471399409548 3367 Glycerophospholipid biosynthesis 9 31 2.900801265796092 0.0037220985548402 Q96N66,Q8NCC3,Q8IV08,Q9NPH0,Q8N2A8,Q9NQZ5,Q9UG56,Q92604,P35790 Processes and pathways Reactome Pathways msigdb_reactome 337,4,37,38,101,415,316,172,213 807,1199,2157,385,1470,1003,213,1233,1359,1911,909,2347,1636,1812,1945,37,101,616,1278,4,2246,2249,172,337,2889,2117,963,1296,38,415,316 0.2897820267826493,0.10157608769830284,-0.23831786606746352,0.6094870655900769,0.005872513874080369,0.19620224214011292,0.961063282020524,0.10157608769830284,0.053860976884978005,-0.13977468780074367,0.24312104666747653,-0.28803660939734893,-0.04239342030431858,-0.09094104587744528,-0.13977468780074367,2.969090607110795,1.6254733747117993,0.4282542060735226,0.10157608769830284,7.298411945543759,-0.23831786606746352,-0.23831786606746352,1.1317712009042973,0.6987063152944422,-0.5412682933157936,-0.18889877938207092,0.24312104666747653,0.10157608769830284,2.969090607110795,0.6094870655900769,0.7429774213920438 3367 Predicted secreted proteins 13 48 2.8976599548782875 0.0037595797036351 Q15165,Q9UM22,P05067,P80303,Q9BUR5,Q9NZ08,P43490,Q9UMX5,O75718,P61916,P30740,Q9HB40,Q02818 Functions Protein Atlas Protein class protein_atlas_protein_class 1,68,190,8,198,47,203,84,201,149,238,28,30 2014,1580,517,3272,201,2774,1472,1882,190,1752,2168,2317,2973,521,728,1342,1608,895,238,203,2697,1780,1631,149,8,2927,30,600,664,284,2616,834,1,3184,3323,2643,3206,1293,198,784,2411,2651,28,47,3324,68,84,2666 -0.18889877938207092,-0.04239342030431858,0.4739196680085796,-1.3470325431471153,1.004045806677848,-0.4899972174116964,0.005872513874080369,-0.13977468780074367,1.046822951105993,-0.09094104587744528,-0.23831786606746352,-0.28803660939734893,-0.6447419635510961,0.4739196680085796,0.3361888423900969,0.053860976884978005,-0.04239342030431858,0.24312104666747653,0.8744716799879915,1.004045806677848,-0.43903817143719953,-0.09094104587744528,-0.04239342030431858,1.257715066848026,6.4338683401100525,-0.5928502525010018,3.2104683932450104,0.4282542060735226,0.38234507015049096,0.7870267798407822,-0.388392317630512,0.2897820267826493,9.185425981910969,-0.9625354940644615,-1.8626090534362079,-0.388392317630512,-1.0165649980725264,0.10157608769830284,1.046822951105993,0.3361888423900969,-0.28803660939734893,-0.388392317630512,3.4129471399409548,2.5777445433602932,-1.8626090534362079,2.0561416638490693,1.7843606013886042,-0.388392317630512 3367 serine protease 9 18 2.885641393261864 0.0039061695722288 Q4J6C6,P42785,P10619,P48147,Q2T9J0,O14773,Q9HB40,P67812,Q16740 Functions Panther Protein class panther_protein_class 245,3,61,170,49,319,28,241,62 319,61,1478,1761,2328,733,3,170,241,62,49,245,2812,366,948,785,28,2141 0.6987063152944422,2.283114015588119,0.005872513874080369,-0.09094104587744528,-0.28803660939734893,0.3361888423900969,7.767211111294991,1.1317712009042973,0.8744716799879915,2.245653162379946,2.5413946027810876,0.8744716799879915,-0.4899972174116964,0.6542105287099975,0.24312104666747653,0.3361888423900969,3.4129471399409548,-0.18889877938207092 3367 Tetratricopeptide-like helical domain superfamily [IPR011990] 14 91 2.8203770705098803 0.0047967248066171 Q6ZXV5,O75153,A0AVF1,Q32P28,Q9Y262,Q5R3I4,Q9H7B4,P13674,Q86US8,O75718,Q96TC7,O00411,Q6DKK2,Q6PGP7 Sequence InterPro Superfamily interpro_homologous_superfamily 267,5,133,11,111,13,14,108,306,201,89,119,94,303 133,1730,1319,119,2670,1198,1088,3122,875,2764,5,201,813,1878,1097,2574,1746,108,391,2187,1617,826,1005,2863,1241,2698,1499,2479,920,1791,2487,1642,1254,1136,833,1799,1519,750,1385,2988,1261,1524,3130,1390,11,13,935,94,2506,436,1156,303,267,1042,335,2096,306,3315,615,685,1549,2948,689,409,849,958,89,2529,2400,2260,3348,1983,1846,2409,2272,2739,14,1563,1565,3210,1193,868,1308,1999,3211,111,2291,1572,1456,804,1576 1.3407193358749927,-0.09094104587744528,0.053860976884978005,1.422977916752635,-0.43903817143719953,0.10157608769830284,0.14902186735214557,-0.8553842121388305,0.24312104666747653,-0.4899972174116964,6.861258766582419,1.004045806677848,0.2897820267826493,-0.13977468780074367,0.14902186735214557,-0.388392317630512,-0.09094104587744528,1.5045080195895706,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,0.2897820267826493,0.19620224214011292,-0.5412682933157936,0.10157608769830284,-0.43903817143719953,0.005872513874080369,-0.3380597911426015,0.24312104666747653,-0.09094104587744528,-0.3380597911426015,-0.04239342030431858,0.10157608769830284,0.14902186735214557,0.2897820267826493,-0.09094104587744528,0.005872513874080369,0.3361888423900969,0.053860976884978005,-0.6447419635510961,0.10157608769830284,0.005872513874080369,-0.8553842121388305,0.053860976884978005,6.0175178435563295,5.47584118755579,0.24312104666747653,1.6654484983059537,-0.3380597911426015,0.5645328647779381,0.14902186735214557,0.7429774213920438,0.8308572620954069,0.19620224214011292,0.6987063152944422,-0.18889877938207092,0.7429774213920438,-1.7460032195660424,0.4282542060735226,0.38234507015049096,0.005872513874080369,-0.5928502525010018,0.38234507015049096,0.6094870655900769,0.2897820267826493,0.24312104666747653,1.7052535001830216,-0.3380597911426015,-0.28803660939734893,-0.23831786606746352,-2.836270967644657,-0.13977468780074367,-0.09094104587744528,-0.28803660939734893,-0.23831786606746352,-0.43903817143719953,5.364443360547954,0.005872513874080369,0.005872513874080369,-1.0165649980725264,0.14902186735214557,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-1.0165649980725264,1.5045080195895706,-0.23831786606746352,0.005872513874080369,0.053860976884978005,0.3361888423900969,0.005872513874080369 3367 Serine protease 8 30 2.809534925980937 0.0049613135691841 P42785,P48147,Q2T9J0,O14773,P34913,P10619,Q9HB40,P67812 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 3,170,49,319,179,61,28,241 2013,319,61,1761,2328,179,733,3,170,1365,1919,915,241,2616,2083,1655,49,2812,486,366,948,1831,954,1054,785,28,2136,2141,1863,575 -0.18889877938207092,0.6987063152944422,2.283114015588119,-0.09094104587744528,-0.28803660939734893,1.0893972532895093,0.3361888423900969,7.767211111294991,1.1317712009042973,0.053860976884978005,-0.13977468780074367,0.24312104666747653,0.8744716799879915,-0.388392317630512,-0.18889877938207092,-0.04239342030431858,2.5413946027810876,-0.4899972174116964,0.5193447980380466,0.6542105287099975,0.24312104666747653,-0.09094104587744528,0.24312104666747653,0.19620224214011292,0.3361888423900969,3.4129471399409548,-0.18889877938207092,-0.18889877938207092,-0.09094104587744528,0.4739196680085796 3367 Endoplasmic reticulum golgi intermediate compartment 13 45 2.791495790119066 0.0052465040130007 Q13190,P80303,Q5VYK3,Q08379,Q96GC9,P07237,P53634,Q12907,O15260,P51572,Q8N511,Q02818,Q9Y282 Localization GO Cellular component msigdb_gocc 396,8,41,75,174,323,328,150,379,393,95,30,31 1324,379,579,2969,1466,423,323,2317,3176,1349,2977,1777,1012,2200,393,2475,328,1781,8,30,75,601,150,396,752,2082,1263,41,1540,95,2820,2643,1416,174,1422,558,1062,636,2548,2424,1312,31,3008,870,1315 0.053860976884978005,0.6094870655900769,0.4282542060735226,-0.6447419635510961,0.005872513874080369,0.5645328647779381,0.6987063152944422,-0.28803660939734893,-0.9625354940644615,0.053860976884978005,-0.6447419635510961,-0.09094104587744528,0.19620224214011292,-0.23831786606746352,0.6094870655900769,-0.3380597911426015,0.6987063152944422,-0.09094104587744528,6.4338683401100525,3.2104683932450104,1.9017911284204507,0.4282542060735226,1.257715066848026,0.6094870655900769,0.3361888423900969,-0.18889877938207092,0.10157608769830284,2.899060884241353,0.005872513874080369,1.6654484983059537,-0.4899972174116964,-0.388392317630512,0.053860976884978005,1.1317712009042973,0.053860976884978005,0.4739196680085796,0.19620224214011292,0.4282542060735226,-0.3380597911426015,-0.28803660939734893,0.10157608769830284,3.2104683932450104,-0.6447419635510961,0.2897820267826493,0.10157608769830284 3367 Molecular transducer activity 8 30 2.7864853355853683 0.00532830288659 Q14108,O15031,Q99720,Q9BUN8,P30536,P20645,Q8WTV0,O15118 Functions GO Molecular function msigdb_gomf 164,103,43,80,113,23,25,125 1580,103,125,189,2765,1751,1759,23,113,904,2334,1239,832,3268,834,164,333,755,2625,1532,2243,25,953,1058,43,80,2546,1997,1305,2555 -0.04239342030431858,1.5450050959353323,1.381940746478781,1.046822951105993,-0.4899972174116964,-0.09094104587744528,-0.09094104587744528,4.123694916854529,1.463832977402664,0.24312104666747653,-0.28803660939734893,0.10157608769830284,0.2897820267826493,-1.2912106707426125,0.2897820267826493,1.1739472326847418,0.6987063152944422,0.3361888423900969,-0.388392317630512,0.005872513874080369,-0.23831786606746352,3.6115632124813404,0.24312104666747653,0.19620224214011292,2.8638632384419833,1.8628092769514064,-0.3380597911426015,-0.13977468780074367,0.10157608769830284,-0.3380597911426015 3367 Steroid binding 8 22 2.6836259038733283 0.0072828547404533 P04062,Q14108,P21796,O15173,P30536,P61916,P45880,O15118 Functions GO Molecular function msigdb_gomf 99,164,100,189,113,149,56,125 1459,125,189,885,99,1597,2450,100,1110,1607,113,429,1358,56,149,164,1145,1175,2532,1296,2535,341 0.005872513874080369,1.381940746478781,1.046822951105993,0.24312104666747653,1.6254733747117993,-0.04239342030431858,-0.3380597911426015,1.6254733747117993,0.14902186735214557,-0.04239342030431858,1.463832977402664,0.5645328647779381,0.053860976884978005,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.14902186735214557,-0.3380597911426015,0.10157608769830284,-0.3380597911426015,0.6987063152944422 3367 Mitochondrial transport 18 77 2.675495741656756 0.0074618821144898 Q9Y276,O75964,O43772,P55786,P36542,Q99496,Q9NRK6,O60830,Q9NS69,O14925,P30536,Q99595,P23786,P45880,P51572,Q96EK5,Q5JRX3,Q9P0J0 Processes and pathways GO Biological process msigdb_gobp 510,33,2,159,297,369,207,12,46,420,113,18,82,56,393,409,402,220 1730,808,420,719,2,12,3100,1206,584,33,1097,3103,1212,2310,1214,727,997,1102,1334,2032,1599,1337,2585,1003,82,1347,2777,2591,3063,113,2331,297,2979,56,2338,1010,1777,3033,1120,828,393,1627,159,742,529,1924,665,2986,1145,483,1390,609,1812,402,938,1670,942,1162,2250,409,960,369,18,2999,2538,207,46,220,2140,1998,867,2283,510,3347,799,801,1575 -0.09094104587744528,0.2897820267826493,0.5645328647779381,0.3361888423900969,8.462226464311355,5.531143228715627,-0.8022645150247569,0.10157608769830284,0.4282542060735226,3.0386401585275027,0.14902186735214557,-0.8022645150247569,0.10157608769830284,-0.28803660939734893,0.10157608769830284,0.3361888423900969,0.19620224214011292,0.14902186735214557,0.053860976884978005,-0.18889877938207092,-0.04239342030431858,0.053860976884978005,-0.388392317630512,0.19620224214011292,1.7843606013886042,0.053860976884978005,-0.4899972174116964,-0.388392317630512,-0.7494501896778172,1.463832977402664,-0.28803660939734893,0.7429774213920438,-0.6447419635510961,2.394640025697565,-0.28803660939734893,0.19620224214011292,-0.09094104587744528,-0.6969423099361801,0.14902186735214557,0.2897820267826493,0.6094870655900769,-0.04239342030431858,1.2159277397438069,0.3361888423900969,0.4739196680085796,-0.13977468780074367,0.38234507015049096,-0.6447419635510961,0.14902186735214557,0.5193447980380466,0.053860976884978005,0.4282542060735226,-0.09094104587744528,0.6094870655900769,0.24312104666747653,-0.04239342030431858,0.24312104666747653,0.14902186735214557,-0.23831786606746352,0.6094870655900769,0.24312104666747653,0.6542105287099975,4.731666431481315,-0.6447419635510961,-0.3380597911426015,1.004045806677848,2.7575257190991964,0.961063282020524,-0.18889877938207092,-0.13977468780074367,0.2897820267826493,-0.23831786606746352,0.5193447980380466,-2.710654339272441,0.3361888423900969,0.3361888423900969,0.005872513874080369 3367 Circulatory system process 15 70 2.594891249118084 0.0094620852611959 P30825,Q6PI78,P42785,P80404,Q9HB40,Q9NZ08,P46734,Q9UIQ6,Q99996,O75844,P78417,Q16625,Q9NRY4,P09601,P42892 Processes and pathways GO Biological process msigdb_gobp 212,195,3,36,28,47,260,19,83,87,242,301,156,60,63 1320,873,2016,517,3153,1468,87,1742,2447,2774,1595,1472,1101,322,1597,2451,60,2318,388,2582,2452,3224,3291,1226,2588,2176,2857,2185,212,2978,3066,826,3,63,260,1010,592,3033,1624,911,2208,1125,2064,242,36,3109,1253,3268,2708,924,667,2076,1142,2497,2230,755,301,1271,195,616,2395,496,1693,83,2650,28,156,47,19,3172 0.053860976884978005,0.24312104666747653,-0.18889877938207092,0.4739196680085796,-0.908808220790615,0.005872513874080369,1.7052535001830216,-0.09094104587744528,-0.3380597911426015,-0.4899972174116964,-0.04239342030431858,0.005872513874080369,0.14902186735214557,0.6987063152944422,-0.04239342030431858,-0.3380597911426015,2.283114015588119,-0.28803660939734893,0.6094870655900769,-0.388392317630512,-0.3380597911426015,-1.1255266262233685,-1.4595613570006674,0.10157608769830284,-0.388392317630512,-0.23831786606746352,-0.5412682933157936,-0.23831786606746352,0.961063282020524,-0.6447419635510961,-0.7494501896778172,0.2897820267826493,7.767211111294991,2.132393733047149,0.8308572620954069,0.19620224214011292,0.4282542060735226,-0.6969423099361801,-0.04239342030431858,0.24312104666747653,-0.23831786606746352,0.14902186735214557,-0.18889877938207092,0.8744716799879915,2.969090607110795,-0.8022645150247569,0.10157608769830284,-1.2912106707426125,-0.43903817143719953,0.24312104666747653,0.38234507015049096,-0.18889877938207092,0.14902186735214557,-0.3380597911426015,-0.23831786606746352,0.3361888423900969,0.7429774213920438,0.10157608769830284,1.046822951105993,0.4282542060735226,-0.28803660939734893,0.5193447980380466,-0.04239342030431858,1.7843606013886042,-0.388392317630512,3.4129471399409548,1.257715066848026,2.5777445433602932,4.4014392320994515,-0.908808220790615 3367 Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 6 31 2.587892272333377 0.0096565175411926 Q32P28,Q16850,P13674,P30519,Q9NVH6,P09601 Functions GO Molecular function msigdb_gomf 11,76,108,53,200,60 1321,2296,3122,1587,517,1467,2312,323,60,108,1340,1900,53,2465,659,1927,1254,2621,193,76,11,2243,675,1157,613,1820,626,2270,200,1077,1455 0.053860976884978005,-0.28803660939734893,-0.8553842121388305,-0.04239342030431858,0.4739196680085796,0.005872513874080369,-0.28803660939734893,0.6987063152944422,2.283114015588119,1.5045080195895706,0.053860976884978005,-0.13977468780074367,2.431534530000306,-0.3380597911426015,0.38234507015049096,-0.13977468780074367,0.10157608769830284,-0.388392317630512,1.046822951105993,1.9017911284204507,6.0175178435563295,-0.23831786606746352,0.38234507015049096,0.14902186735214557,0.4282542060735226,-0.09094104587744528,0.4282542060735226,-0.23831786606746352,1.046822951105993,0.19620224214011292,0.053860976884978005 3367 Glycerolipid biosynthetic process 11 47 2.571815263439237 0.0101166858605949 Q96Q15,Q96N66,Q8NCC3,Q9H490,Q9NPH0,Q9UG56,Q96S52,Q92604,Q8WTV0,P42356,P35790 Processes and pathways GO Biological process msigdb_gobp 64,337,4,313,38,316,175,172,25,239,213 873,807,1199,2673,3055,887,385,2311,1470,818,3225,2188,213,239,1911,1926,665,835,606,2086,674,335,1945,4,2246,3136,25,2249,1048,172,1548,623,1413,337,64,175,2889,555,963,2402,1844,2405,313,38,2543,316,1312 0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.7494501896778172,0.24312104666747653,0.6094870655900769,-0.28803660939734893,0.005872513874080369,0.2897820267826493,-1.1255266262233685,-0.23831786606746352,0.961063282020524,0.8744716799879915,-0.13977468780074367,-0.13977468780074367,0.38234507015049096,0.2897820267826493,0.4282542060735226,-0.18889877938207092,0.38234507015049096,0.6987063152944422,-0.13977468780074367,7.298411945543759,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,-0.23831786606746352,0.19620224214011292,1.1317712009042973,0.005872513874080369,0.4282542060735226,0.053860976884978005,0.6987063152944422,2.132393733047149,1.1317712009042973,-0.5412682933157936,0.4739196680085796,0.24312104666747653,-0.28803660939734893,-0.09094104587744528,-0.28803660939734893,0.7429774213920438,2.969090607110795,-0.3380597911426015,0.7429774213920438,0.10157608769830284 3367 Proteasome degradation 8 42 2.5562732880627848 0.0105799989095951 P60900,P28074,P16104,P20618,P49721,P28072,P61289,P01889 Processes and pathways WikiPathways msigdb_wp 128,35,158,192,10,52,283,126 1319,2436,2567,875,2846,126,424,1883,815,1601,158,1343,192,1486,2458,2179,2041,1895,1771,647,52,35,2193,2197,908,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,1.381940746478781,0.5645328647779381,-0.13977468780074367,0.2897820267826493,-0.04239342030431858,1.2159277397438069,0.053860976884978005,1.046822951105993,0.005872513874080369,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.24312104666747653,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Mitochondrial transmembrane transport 6 45 2.549779207068969 0.010779116042239 O75964,O43772,P21796,O60830,Q99595,P23786 Processes and pathways GO Biological process msigdb_gobp 33,2,100,12,18,82 420,719,2,12,2910,1206,1095,584,33,1097,519,1880,1214,727,1102,1334,1337,2585,470,100,82,1347,2777,297,2338,828,1917,742,529,478,609,3288,1952,2391,2250,18,3353,500,105,3281,1438,2538,867,2283,3012 0.5645328647779381,0.3361888423900969,8.462226464311355,5.531143228715627,-0.5928502525010018,0.10157608769830284,0.14902186735214557,0.4282542060735226,3.0386401585275027,0.14902186735214557,0.4739196680085796,-0.13977468780074367,0.10157608769830284,0.3361888423900969,0.14902186735214557,0.053860976884978005,0.053860976884978005,-0.388392317630512,0.5193447980380466,1.6254733747117993,1.7843606013886042,0.053860976884978005,-0.4899972174116964,0.7429774213920438,-0.28803660939734893,0.2897820267826493,-0.13977468780074367,0.3361888423900969,0.4739196680085796,0.5193447980380466,0.4282542060735226,-1.403149751562867,-0.13977468780074367,-0.28803660939734893,-0.23831786606746352,4.731666431481315,-3.5466505530698798,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.053860976884978005,-0.3380597911426015,0.2897820267826493,-0.23831786606746352,-0.6447419635510961 3367 Regulation of nervous system process 6 14 2.534646301507735 0.0112560913653176 Q9UQB8,P04062,P80404,P05067,Q14118,Q99996 Processes and pathways GO Biological process msigdb_gobp 0,99,36,190,263,83 3153,1095,99,190,2779,328,36,1793,606,263,1937,83,979,0 -0.908808220790615,0.14902186735214557,1.6254733747117993,1.046822951105993,-0.4899972174116964,0.6987063152944422,2.969090607110795,-0.09094104587744528,0.4282542060735226,0.8308572620954069,-0.13977468780074367,1.7843606013886042,0.24312104666747653,9.674117275578304 3367 Exopeptidase activity 6 31 2.531590229814664 0.0113546599198433 P42785,Q9NZ08,Q9UIQ6,O75844,P10619,Q9HB40 Functions GO Molecular function msigdb_gomf 3,47,19,87,61,28 319,87,644,1472,2917,61,1224,2778,2328,901,3,3226,328,159,2707,2619,2812,2991,2393,624,3202,959,2117,785,2411,28,1186,2414,701,47,19 0.6987063152944422,1.7052535001830216,0.38234507015049096,0.005872513874080369,-0.5928502525010018,2.283114015588119,0.10157608769830284,-0.4899972174116964,-0.28803660939734893,0.24312104666747653,7.767211111294991,-1.1255266262233685,0.6987063152944422,1.2159277397438069,-0.43903817143719953,-0.388392317630512,-0.4899972174116964,-0.6447419635510961,-0.28803660939734893,0.4282542060735226,-1.0165649980725264,0.24312104666747653,-0.18889877938207092,0.3361888423900969,-0.28803660939734893,3.4129471399409548,0.14902186735214557,-0.28803660939734893,0.38234507015049096,2.5777445433602932,4.4014392320994515 3367 Synaptic membrane 6 43 2.505260823878323 0.0122361123857113 Q9UQB8,Q99720,Q14118,Q12846,Q99996,Q9UQ16 Localization GO Cellular component msigdb_gocc 0,43,263,114,83,187 2758,1580,2018,2845,580,1874,1751,1886,1219,1220,2680,294,2588,1350,898,1117,525,1914,1364,1793,114,3072,1138,606,263,1802,1937,2085,1827,683,1412,1682,443,43,83,2263,2402,2541,2552,187,0,708,800 -0.4899972174116964,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,0.4282542060735226,-0.13977468780074367,-0.09094104587744528,-0.13977468780074367,0.10157608769830284,0.10157608769830284,-0.43903817143719953,0.7429774213920438,-0.388392317630512,0.053860976884978005,0.24312104666747653,0.14902186735214557,0.4739196680085796,-0.13977468780074367,0.053860976884978005,-0.09094104587744528,1.463832977402664,-0.7494501896778172,0.14902186735214557,0.4282542060735226,0.8308572620954069,-0.09094104587744528,-0.13977468780074367,-0.18889877938207092,-0.09094104587744528,0.38234507015049096,0.053860976884978005,-0.04239342030431858,0.5645328647779381,2.8638632384419833,1.7843606013886042,-0.23831786606746352,-0.28803660939734893,-0.3380597911426015,-0.3380597911426015,1.0893972532895093,9.674117275578304,0.38234507015049096,0.3361888423900969 3367 Copii coated er to golgi transport vesicle 12 29 2.4651063798688893 0.0136972578461931 O95070,O15027,P05067,Q5VYK3,Q08379,O95487,P53634,Q12907,P01889,P04439,Q13190,Q9Y282 Localization GO Cellular component msigdb_gocc 423,275,190,41,75,466,328,150,126,424,396,31 275,1205,2302,1466,994,423,996,466,126,424,190,1601,1777,1012,328,1498,3128,75,150,396,1388,1807,41,558,972,3168,31,3008,1315 0.7870267798407822,0.10157608769830284,-0.28803660939734893,0.005872513874080369,0.19620224214011292,0.5645328647779381,0.19620224214011292,0.5193447980380466,1.381940746478781,0.5645328647779381,1.046822951105993,-0.04239342030431858,-0.09094104587744528,0.19620224214011292,0.6987063152944422,0.005872513874080369,-0.8553842121388305,1.9017911284204507,1.257715066848026,0.6094870655900769,0.053860976884978005,-0.09094104587744528,2.899060884241353,0.4739196680085796,0.24312104666747653,-0.908808220790615,3.2104683932450104,-0.6447419635510961,0.10157608769830284 3367 Antigen processing cross presentation 7 50 2.463650901936058 0.0137529989404954 P60900,P28074,P49721,Q12846,Q9UIQ6,P28072,P01889 Processes and pathways Reactome Pathways msigdb_reactome 128,35,10,114,19,52,126 1319,2436,2437,2567,987,2969,875,1466,2846,126,424,2317,1601,1343,192,2458,2179,2041,1895,1349,1771,647,52,35,2329,2193,2197,1011,354,10,1244,2699,3298,2924,128,283,1249,1504,2609,2065,1792,114,1797,481,1524,2824,2258,19,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.19620224214011292,-0.6447419635510961,0.24312104666747653,0.005872513874080369,-0.5412682933157936,1.381940746478781,0.5645328647779381,-0.28803660939734893,-0.04239342030431858,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,0.053860976884978005,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.28803660939734893,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-1.516266431277383,-0.5928502525010018,1.381940746478781,0.7870267798407822,0.10157608769830284,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,1.463832977402664,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,4.4014392320994515,0.4282542060735226,-0.28803660939734893 3367 Anion transport 22 59 2.4548902385899307 0.0140927610948571 P51798,Q9HC21,Q9C0H2,P11166,Q9UHG3,P80404,Q9NZJ7,P14174,P28288,P45880,O60831,Q8TB61,Q6N075,P30825,Q9Y696,P21796,P12236,Q9H2D1,O75915,P30536,P07602,Q00325 Processes and pathways GO Biological process msigdb_gobp 475,413,145,388,32,36,315,521,428,56,320,367,363,212,237,100,470,105,226,113,468,478 2295,2016,1201,722,320,1095,226,1880,1882,1102,1751,468,2451,890,2849,388,2585,470,521,100,428,113,212,2978,56,475,1917,911,2207,2208,36,478,533,2986,1380,753,1654,1033,755,363,938,1271,367,1693,145,1561,105,3281,1438,413,2741,315,1998,32,2550,867,980,2841,237 -0.28803660939734893,-0.18889877938207092,0.10157608769830284,0.3361888423900969,0.6987063152944422,0.14902186735214557,0.9178727874245445,-0.13977468780074367,-0.13977468780074367,0.14902186735214557,-0.09094104587744528,0.5193447980380466,-0.3380597911426015,0.24312104666747653,-0.5412682933157936,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.4739196680085796,1.6254733747117993,0.5645328647779381,1.463832977402664,0.961063282020524,-0.6447419635510961,2.394640025697565,0.5193447980380466,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,-0.23831786606746352,2.969090607110795,0.5193447980380466,0.4739196680085796,-0.6447419635510961,0.053860976884978005,0.3361888423900969,-0.04239342030431858,0.19620224214011292,0.3361888423900969,0.6542105287099975,0.24312104666747653,0.10157608769830284,0.6542105287099975,-0.04239342030431858,1.2993115136492674,0.005872513874080369,1.5450050959353323,-1.3470325431471153,0.053860976884978005,0.6094870655900769,-0.43903817143719953,0.7429774213920438,-0.13977468780074367,3.073237531524794,-0.3380597911426015,0.2897820267826493,0.24312104666747653,-0.4899972174116964,0.9178727874245445 3367 Cholesterol binding 7 14 2.442321265326261 0.0145931537413162 Q14108,P21796,P30536,P61916,P45880,O15118,Q9H4L5 Functions GO Molecular function msigdb_gomf 164,100,113,149,56,125,341 125,885,2450,100,1607,113,429,56,149,164,1145,1296,2535,341 1.381940746478781,0.24312104666747653,-0.3380597911426015,1.6254733747117993,-0.04239342030431858,1.463832977402664,0.5645328647779381,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.10157608769830284,-0.3380597911426015,0.6987063152944422 3367 Transporter activity 26 144 2.438682291004861 0.0147409218273284 O43772,O60830,Q9C0H2,Q99595,P61916,Q8IXU6,Q8WTV0,O75964,Q96GC9,Q70HW3,Q9NS69,Q9HD20,O43676,P45880,Q9BVC6,O15173,Q9NRK6,Q9P0J0,P30825,P04062,P21796,Q9H2D1,P30536,Q9UDW1,P21281,O15118 Functions GO Molecular function msigdb_gomf 2,12,145,18,149,22,25,33,174,45,46,51,55,56,65,189,207,220,212,99,100,105,113,118,121,125 2842,3338,2295,1460,2016,420,3096,125,189,2969,55,1201,2,722,12,2910,1874,1465,2025,1095,584,33,1097,3290,2027,519,3102,1880,3349,727,1471,99,1597,1102,1334,2168,2450,2451,890,1336,2849,2319,388,2585,470,1000,1226,1889,1605,2588,2322,121,588,100,1110,1347,2777,428,2590,113,212,1615,297,1905,1358,1492,2978,56,3191,2338,909,1012,2864,475,527,1625,1365,1917,911,2208,742,529,3298,532,1249,149,746,478,533,3156,926,2229,1145,1033,755,839,1530,363,2376,938,1271,1397,45,22,1827,768,1952,367,25,953,3163,174,1175,1692,18,1693,2117,500,65,2532,1296,145,2898,2535,105,341,3281,1438,413,51,207,46,220,1998,118,1305,372,867,3007,3289,980,2006,237,1457 -0.5412682933157936,-2.2192938988489903,-0.28803660939734893,0.005872513874080369,-0.18889877938207092,0.5645328647779381,-0.8022645150247569,1.381940746478781,1.046822951105993,-0.6447419635510961,2.394640025697565,0.10157608769830284,8.462226464311355,0.3361888423900969,5.531143228715627,-0.5928502525010018,-0.13977468780074367,0.005872513874080369,-0.18889877938207092,0.14902186735214557,0.4282542060735226,3.0386401585275027,0.14902186735214557,-1.4595613570006674,-0.18889877938207092,0.4739196680085796,-0.8022645150247569,-0.13977468780074367,-2.8994916636965624,0.3361888423900969,0.005872513874080369,1.6254733747117993,-0.04239342030431858,0.14902186735214557,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,-0.3380597911426015,0.24312104666747653,0.053860976884978005,-0.5412682933157936,-0.28803660939734893,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.19620224214011292,0.10157608769830284,-0.13977468780074367,-0.04239342030431858,-0.388392317630512,-0.28803660939734893,1.422977916752635,0.4282542060735226,1.6254733747117993,0.14902186735214557,0.053860976884978005,-0.4899972174116964,0.5645328647779381,-0.388392317630512,1.463832977402664,0.961063282020524,-0.04239342030431858,0.7429774213920438,-0.13977468780074367,0.053860976884978005,0.005872513874080369,-0.6447419635510961,2.394640025697565,-1.0165649980725264,-0.28803660939734893,0.24312104666747653,0.19620224214011292,-0.5412682933157936,0.5193447980380466,0.4739196680085796,-0.04239342030431858,0.053860976884978005,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,0.3361888423900969,0.4739196680085796,-1.516266431277383,0.4739196680085796,0.10157608769830284,1.257715066848026,0.3361888423900969,0.5193447980380466,0.4739196680085796,-0.908808220790615,0.24312104666747653,-0.23831786606746352,0.14902186735214557,0.19620224214011292,0.3361888423900969,0.2897820267826493,0.005872513874080369,0.6542105287099975,-0.28803660939734893,0.24312104666747653,0.10157608769830284,0.053860976884978005,2.7575257190991964,4.1860297014667704,-0.09094104587744528,0.3361888423900969,-0.13977468780074367,0.6542105287099975,3.6115632124813404,0.24312104666747653,-0.908808220790615,1.1317712009042973,0.14902186735214557,-0.04239342030431858,4.731666431481315,-0.04239342030431858,-0.18889877938207092,0.5193447980380466,2.0943433015075343,-0.3380597911426015,0.10157608769830284,1.2993115136492674,-0.5412682933157936,-0.3380597911426015,1.5450050959353323,0.6987063152944422,-1.3470325431471153,0.053860976884978005,0.6094870655900769,2.5049104893301823,1.004045806677848,2.7575257190991964,0.961063282020524,-0.13977468780074367,1.463832977402664,0.10157608769830284,0.6542105287099975,0.2897820267826493,-0.6447419635510961,-1.403149751562867,0.24312104666747653,-0.13977468780074367,0.9178727874245445,0.053860976884978005 3367 Lipid homeostasis 11 23 2.4337367852417744 0.0149438576402061 Q9NQC3,P35610,P34913,O15254,Q6IAA8,P61916,O15118,Q5BJF2,Q8WTV0,O15260,Q9UHB6 Processes and pathways GO Biological process msigdb_gobp 129,429,179,73,266,149,125,24,25,379,507 1577,125,73,379,996,2920,2043,179,429,149,2870,2986,2501,24,266,1666,25,2254,559,129,507,2748,2012 -0.04239342030431858,1.381940746478781,1.9792784396533925,0.6094870655900769,0.19620224214011292,-0.5928502525010018,-0.18889877938207092,1.0893972532895093,0.5645328647779381,1.257715066848026,-0.5412682933157936,-0.6447419635510961,-0.3380597911426015,3.9345059665079796,0.8308572620954069,-0.04239342030431858,3.6115632124813404,-0.23831786606746352,0.4739196680085796,1.381940746478781,0.5193447980380466,-0.43903817143719953,-0.13977468780074367 3367 SLC superfamily of solute carriers 14 38 2.432633597222424 0.0149894606298146 P30825,O43772,Q9HC21,P12236,O95202,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q8IXU6,Q00325,P11166,Q8TB61,Q6N075 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 212,2,413,470,519,105,315,45,500,22,478,388,367,363 3096,2,722,1095,519,1880,1102,890,388,2585,470,212,2978,1917,911,2208,478,533,1033,755,363,2376,938,1271,45,22,367,1693,500,2898,105,3281,1438,413,315,1998,867,2012 -0.8022645150247569,8.462226464311355,0.3361888423900969,0.14902186735214557,0.4739196680085796,-0.13977468780074367,0.14902186735214557,0.24312104666747653,0.6094870655900769,-0.388392317630512,0.5193447980380466,0.961063282020524,-0.6447419635510961,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,0.5193447980380466,0.4739196680085796,0.19620224214011292,0.3361888423900969,0.6542105287099975,-0.28803660939734893,0.24312104666747653,0.10157608769830284,2.7575257190991964,4.1860297014667704,0.6542105287099975,-0.04239342030431858,0.5193447980380466,-0.5412682933157936,1.5450050959353323,-1.3470325431471153,0.053860976884978005,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367 3367 Glycerophospholipid metabolic process 13 59 2.4268136298364924 0.015232078361909 Q96Q15,Q96N66,Q8NCC3,Q9H490,Q9NPH0,Q9UG56,Q96S52,Q86TV6,Q92604,Q8N9F7,Q8WTV0,P42356,P35790 Processes and pathways GO Biological process msigdb_gobp 64,337,4,313,38,316,175,335,172,307,25,239,213 1317,873,807,1199,2673,3055,887,385,2311,1470,818,1890,3225,1613,213,1233,239,1909,1911,1624,1926,665,835,606,674,335,1945,3258,366,307,4,2246,3136,25,2249,1048,172,1548,623,1413,337,64,175,2889,555,1838,963,2402,1844,2405,1296,2123,313,38,2543,793,316,2283,1312 0.053860976884978005,0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.7494501896778172,0.24312104666747653,0.6094870655900769,-0.28803660939734893,0.005872513874080369,0.2897820267826493,-0.13977468780074367,-1.1255266262233685,-0.04239342030431858,0.961063282020524,0.10157608769830284,0.8744716799879915,-0.13977468780074367,-0.13977468780074367,-0.04239342030431858,-0.13977468780074367,0.38234507015049096,0.2897820267826493,0.4282542060735226,0.38234507015049096,0.6987063152944422,-0.13977468780074367,-1.2356850843636273,0.6542105287099975,0.7429774213920438,7.298411945543759,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,-0.23831786606746352,0.19620224214011292,1.1317712009042973,0.005872513874080369,0.4282542060735226,0.053860976884978005,0.6987063152944422,2.132393733047149,1.1317712009042973,-0.5412682933157936,0.4739196680085796,-0.09094104587744528,0.24312104666747653,-0.28803660939734893,-0.09094104587744528,-0.28803660939734893,0.10157608769830284,-0.18889877938207092,0.7429774213920438,2.969090607110795,-0.3380597911426015,0.3361888423900969,0.7429774213920438,-0.23831786606746352,0.10157608769830284 3367 Abnormal epiphyseal ossification 6 17 2.363779333411669 0.0180895837691188 O43933,Q15125,Q2M1P5,Q9UBM7,Q14739,Q96L58 Drugs and Diseases Human Phenotype Ontology msigdb_hp 98,74,205,54,151,215 2669,98,1739,882,1222,1358,530,151,2711,74,1938,205,958,1172,215,54,316 -0.43903817143719953,1.6254733747117993,-0.09094104587744528,0.24312104666747653,0.10157608769830284,0.053860976884978005,0.4739196680085796,1.257715066848026,-0.43903817143719953,1.9792784396533925,-0.13977468780074367,1.004045806677848,0.24312104666747653,0.14902186735214557,0.961063282020524,2.431534530000306,0.7429774213920438 3367 Supranuclear gaze palsy 10 20 2.3620132373480582 0.0181759931799139 Q96RL7,Q969N2,P04062,Q96RR1,Q99720,Q9NZJ7,P07602,P35637,P61916,O15118 Drugs and Diseases Human Phenotype Ontology msigdb_hp 216,623,99,553,43,315,468,326,149,125 2438,986,125,99,468,1756,1901,326,2346,149,603,1648,1650,623,216,553,43,315,1451,797 -0.3380597911426015,0.19620224214011292,1.381940746478781,1.6254733747117993,0.5193447980380466,-0.09094104587744528,-0.13977468780074367,0.6987063152944422,-0.28803660939734893,1.257715066848026,0.4282542060735226,-0.04239342030431858,-0.04239342030431858,0.4282542060735226,0.961063282020524,0.4739196680085796,2.8638632384419833,0.7429774213920438,0.053860976884978005,0.3361888423900969 3367 Sterol homeostasis 7 11 2.358284196323975 0.0183596312286982 P35610,Q6IAA8,P61916,Q5BJF2,Q8WTV0,P34913,O15118 Processes and pathways GO Biological process msigdb_gobp 429,266,149,24,25,179,125 125,996,179,429,149,24,266,25,2254,507,2748 1.381940746478781,0.19620224214011292,1.0893972532895093,0.5645328647779381,1.257715066848026,3.9345059665079796,0.8308572620954069,3.6115632124813404,-0.23831786606746352,0.5193447980380466,-0.43903817143719953 3367 Sterol binding 7 17 2.35257090149917 0.0186441350050885 Q14108,P21796,P30536,P61916,P45880,O15118,Q9H4L5 Functions GO Molecular function msigdb_gomf 164,100,113,149,56,125,341 125,885,2450,100,1110,1607,113,429,56,149,164,1145,1175,2532,1296,2535,341 1.381940746478781,0.24312104666747653,-0.3380597911426015,1.6254733747117993,0.14902186735214557,-0.04239342030431858,1.463832977402664,0.5645328647779381,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.14902186735214557,-0.3380597911426015,0.10157608769830284,-0.3380597911426015,0.6987063152944422 3367 Defective cftr causes cystic fibrosis 7 39 2.3376685216869677 0.0194044503312758 P60900,P28074,P20618,P49721,Q9BUN8,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,80,52,283 1319,2436,2437,2567,875,2846,885,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,2346,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,80,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.24312104666747653,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,1.8628092769514064,0.4282542060735226,-0.28803660939734893 3367 Abc transporter disorders 7 39 2.3376685216869677 0.0194044503312758 P60900,P28074,P20618,P49721,Q9BUN8,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,80,52,283 1319,2436,2437,2567,875,2846,885,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,2346,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,80,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.24312104666747653,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,1.8628092769514064,0.4282542060735226,-0.28803660939734893 3367 Amide binding 27 104 2.329853285324864 0.0198139067503073 Q02252,Q9UIQ6,O60684,Q8WTV0,Q9BYT8,P55786,Q9H2P0,Q9NZJ7,Q9NZ08,Q9NXR7,P45880,P55899,P00374,P04439,P42892,P35610,Q9UM22,Q9Y680,Q92947,Q13427,Q14978,Q99735,O14773,P21796,P49748,P07602,P01889 Functions GO Molecular function msigdb_gomf 136,19,382,25,154,159,447,315,47,452,56,180,59,424,63,429,68,69,494,88,332,217,319,100,230,468,126 2435,577,1459,1197,806,2439,319,2969,2154,2765,382,2304,1097,59,126,424,3021,1749,468,1753,1219,1220,1601,2320,728,2854,100,1607,1608,3176,1770,1349,2857,2591,2184,2977,429,900,1356,1233,2978,63,906,56,2339,1239,230,1013,1241,2473,1364,3252,1365,159,180,2059,1249,2349,1511,1023,746,832,136,1791,3228,3268,3218,1642,1257,88,1519,1138,2081,332,3232,2632,2106,25,494,775,777,1833,1415,2823,554,1838,217,2267,154,447,3117,2128,2412,452,47,315,1306,2746,19,68,2002,1080,3011,69 -0.3380597911426015,0.4282542060735226,0.005872513874080369,0.10157608769830284,0.2897820267826493,-0.3380597911426015,0.6987063152944422,-0.6447419635510961,-0.23831786606746352,-0.4899972174116964,0.6094870655900769,-0.28803660939734893,0.14902186735214557,2.283114015588119,1.381940746478781,0.5645328647779381,-0.6969423099361801,-0.09094104587744528,0.5193447980380466,-0.09094104587744528,0.10157608769830284,0.10157608769830284,-0.04239342030431858,-0.28803660939734893,0.3361888423900969,-0.5412682933157936,1.6254733747117993,-0.04239342030431858,-0.04239342030431858,-0.9625354940644615,-0.09094104587744528,0.053860976884978005,-0.5412682933157936,-0.388392317630512,-0.23831786606746352,-0.6447419635510961,0.5645328647779381,0.24312104666747653,0.053860976884978005,0.10157608769830284,-0.6447419635510961,2.132393733047149,0.24312104666747653,2.394640025697565,-0.28803660939734893,0.10157608769830284,0.9178727874245445,0.19620224214011292,0.10157608769830284,-0.3380597911426015,0.053860976884978005,-1.2356850843636273,0.053860976884978005,1.2159277397438069,1.0893972532895093,-0.18889877938207092,0.10157608769830284,-0.28803660939734893,0.005872513874080369,0.19620224214011292,0.3361888423900969,0.2897820267826493,1.3407193358749927,-0.09094104587744528,-1.1255266262233685,-1.2912106707426125,-1.070895711677453,-0.04239342030431858,0.10157608769830284,1.7052535001830216,0.005872513874080369,0.14902186735214557,-0.18889877938207092,0.6987063152944422,-1.1255266262233685,-0.388392317630512,-0.18889877938207092,3.6115632124813404,0.5193447980380466,0.3361888423900969,0.3361888423900969,-0.09094104587744528,0.053860976884978005,-0.4899972174116964,0.4739196680085796,-0.09094104587744528,0.961063282020524,-0.23831786606746352,1.257715066848026,0.5645328647779381,-0.8022645150247569,-0.18889877938207092,-0.28803660939734893,0.5645328647779381,2.5777445433602932,0.7429774213920438,0.10157608769830284,-0.43903817143719953,4.4014392320994515,2.0561416638490693,-0.13977468780074367,0.19620224214011292,-0.6447419635510961,2.0561416638490693 3367 Glycolipid binding 6 9 2.3233683714226108 0.0201593717128172 Q9UM22,Q9H490,Q9NZJ7,P50897,P54652,O14773 Functions GO Molecular function msigdb_gomf 68,313,315,261,329,319 319,468,261,329,1631,1548,313,315,68 0.6987063152944422,0.5193447980380466,0.8308572620954069,0.6987063152944422,-0.04239342030431858,0.005872513874080369,0.7429774213920438,0.7429774213920438,2.0561416638490693 3367 Rac3 gtpase cycle 8 33 2.3136777284786683 0.0206854064524548 Q9UQB8,O15173,Q6IAA8,O75962,Q7L576,Q14739,Q9NRY4,P50402 Processes and pathways Reactome Pathways msigdb_reactome 0,189,266,352,305,151,156,214 189,579,352,1472,1751,2582,1116,736,3251,1777,214,1014,1125,1926,358,2617,1796,1142,151,755,3242,1268,266,305,2395,1976,1697,1561,156,2277,0,869,2429 1.046822951105993,0.4282542060735226,0.6542105287099975,0.005872513874080369,-0.09094104587744528,-0.388392317630512,0.14902186735214557,0.3361888423900969,-1.2356850843636273,-0.09094104587744528,0.961063282020524,0.19620224214011292,0.14902186735214557,-0.13977468780074367,0.6542105287099975,-0.388392317630512,-0.09094104587744528,0.14902186735214557,1.257715066848026,0.3361888423900969,-1.1804567452748522,0.10157608769830284,0.8308572620954069,0.7429774213920438,-0.28803660939734893,-0.13977468780074367,-0.04239342030431858,0.005872513874080369,1.257715066848026,-0.23831786606746352,9.674117275578304,0.2897820267826493,-0.28803660939734893 3367 Snare complex 8 13 2.3118756936132105 0.0207845345535733 Q86Y82,O15400,O43752,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190 Localization GO Cellular component msigdb_gocc 196,276,516,177,228,114,505,396 276,579,516,1466,228,1499,114,925,396,196,2260,505,177 0.7870267798407822,0.4282542060735226,0.4739196680085796,0.005872513874080369,0.9178727874245445,0.005872513874080369,1.463832977402664,0.24312104666747653,0.6094870655900769,1.046822951105993,-0.23831786606746352,0.5193447980380466,1.1317712009042973 3367 Regulation of hmox1 expression and activity 10 47 2.3102873878295385 0.0208722487132331 P60900,P28074,Q13309,Q8TCT9,P20618,P49721,P49720,P28072,P61289,P09601 Processes and pathways Reactome Pathways msigdb_reactome 128,35,232,235,192,10,354,52,283,60 1319,2436,2437,2567,2968,875,2846,60,1343,1003,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,394,1636,2352,1792,1797,232,3241,2492,1258,481,1524,235,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.6447419635510961,0.24312104666747653,-0.5412682933157936,2.283114015588119,0.053860976884978005,0.19620224214011292,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.04239342030431858,-0.28803660939734893,-0.09094104587744528,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.3380597911426015,0.10157608769830284,0.5193447980380466,0.005872513874080369,0.9178727874245445,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Switching of origins to a post replicative state 14 58 2.30986789940136 0.020895468743044 P60900,P28074,P30260,Q13309,P20618,P49721,Q99741,Q9UJX6,P49720,Q96DE5,P28072,Q9UBD5,P61289,P63208 Processes and pathways Reactome Pathways msigdb_reactome 128,35,391,232,192,10,498,317,354,96,52,221,283,394 1319,2436,2437,2567,875,1586,2846,1343,192,1229,2325,2458,2179,2041,1895,1771,647,52,35,391,2190,1618,2046,2193,2197,1011,354,10,1496,1244,2699,128,283,1504,2609,2065,394,1792,833,1797,232,3241,1934,481,1524,1810,96,2824,2258,498,221,868,1308,1999,2661,317,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,0.2897820267826493,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,0.5193447980380466,0.005872513874080369,-0.09094104587744528,1.6654484983059537,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,0.961063282020524,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-0.388392317630512,0.7429774213920438,0.4282542060735226,-0.28803660939734893 3367 Snap receptor activity 8 11 2.29944210857576 0.0214798471513986 Q86Y82,O15400,O43752,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190 Functions GO Molecular function msigdb_gomf 196,276,516,177,228,114,505,396 276,579,516,1466,228,114,925,396,196,505,177 0.7870267798407822,0.4282542060735226,0.4739196680085796,0.005872513874080369,0.9178727874245445,1.463832977402664,0.24312104666747653,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973 3367 Snare interactions in vesicular transport 8 11 2.29944210857576 0.0214798471513986 Q86Y82,O15400,O43752,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190 Processes and pathways KEGG Pathways msigdb_kegg 196,276,516,177,228,114,505,396 276,579,516,1466,228,114,925,396,196,505,177 0.7870267798407822,0.4282542060735226,0.4739196680085796,0.005872513874080369,0.9178727874245445,1.463832977402664,0.24312104666747653,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973 3367 Regulation of lipid metabolic process 14 53 2.295897165202833 0.0216817618800599 P49748,Q6IAA8,Q9NZJ7,Q92604,P30536,Q2T9J0,Q96G23,P61916,Q9UBM7,O75844,Q8WTV0,P34913,O95822,P83111 Processes and pathways GO Biological process msigdb_gobp 230,266,315,172,113,49,20,149,54,87,25,179,280,243 2439,2571,3286,463,87,1877,885,887,280,1882,1597,468,469,1340,818,113,589,179,590,826,230,828,1124,1125,149,243,2793,2352,2986,3195,835,606,837,754,932,49,1534,266,2246,3136,25,172,2254,20,337,555,1838,315,54,2424,2549,2283,3211 -0.3380597911426015,-0.388392317630512,-1.403149751562867,0.5193447980380466,1.7052535001830216,-0.13977468780074367,0.24312104666747653,0.24312104666747653,0.7870267798407822,-0.13977468780074367,-0.04239342030431858,0.5193447980380466,0.5193447980380466,0.053860976884978005,0.2897820267826493,1.463832977402664,0.4282542060735226,1.0893972532895093,0.4282542060735226,0.2897820267826493,0.9178727874245445,0.2897820267826493,0.14902186735214557,0.14902186735214557,1.257715066848026,0.8744716799879915,-0.4899972174116964,-0.28803660939734893,-0.6447419635510961,-1.0165649980725264,0.2897820267826493,0.4282542060735226,0.2897820267826493,0.3361888423900969,0.24312104666747653,2.5413946027810876,0.005872513874080369,0.8308572620954069,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,1.1317712009042973,-0.23831786606746352,4.309639278406814,0.6987063152944422,0.4739196680085796,-0.09094104587744528,0.7429774213920438,2.431534530000306,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-1.0165649980725264 3367 Cell recognition 7 26 2.290455083543911 0.0219949495071187 Q9NQC3,P05067,Q08431,O14967,P45880,Q8WTV0,Q9NRY4 Processes and pathways GO Biological process msigdb_gobp 129,190,284,211,56,25,156 1580,211,720,2165,190,1342,2175,1004,825,2335,56,2781,2470,2201,2202,2350,2218,284,331,1532,2243,25,2522,2261,129,156 -0.04239342030431858,0.961063282020524,0.3361888423900969,-0.23831786606746352,1.046822951105993,0.053860976884978005,-0.23831786606746352,0.19620224214011292,0.2897820267826493,-0.28803660939734893,2.394640025697565,-0.4899972174116964,-0.3380597911426015,-0.23831786606746352,-0.23831786606746352,-0.28803660939734893,-0.23831786606746352,0.7870267798407822,0.6987063152944422,0.005872513874080369,-0.23831786606746352,3.6115632124813404,-0.3380597911426015,-0.23831786606746352,1.381940746478781,1.257715066848026 3367 Hedgehog on state 8 42 2.2879213052820835 0.0221421043431531 P60900,P28074,P20618,P49721,Q9Y496,Q2M1P5,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,318,205,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,653,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2492,481,1524,205,2879,1174,2824,2258,638,2426,318 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.38234507015049096,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.3380597911426015,0.5193447980380466,0.005872513874080369,1.004045806677848,-0.5412682933157936,0.14902186735214557,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893,0.7429774213920438 3367 Glycerolipid metabolic process 13 65 2.287344412958919 0.0221757280806655 Q96Q15,Q96N66,Q8NCC3,Q9H490,Q9NPH0,Q9UG56,Q96S52,Q86TV6,Q92604,Q8N9F7,Q8WTV0,P42356,P35790 Processes and pathways GO Biological process msigdb_gobp 64,337,4,313,38,316,175,335,172,307,25,239,213 1317,873,807,1199,2673,3055,887,385,2311,1470,818,1890,3225,1613,2188,213,1233,239,1909,1911,828,1624,1926,2984,665,835,606,2086,1812,674,335,1945,3258,366,307,4,2246,3136,25,2249,1048,172,1548,623,1413,2254,337,64,175,2889,555,1838,963,2402,1844,2405,1296,2123,313,38,2543,793,316,2283,1312 0.053860976884978005,0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.7494501896778172,0.24312104666747653,0.6094870655900769,-0.28803660939734893,0.005872513874080369,0.2897820267826493,-0.13977468780074367,-1.1255266262233685,-0.04239342030431858,-0.23831786606746352,0.961063282020524,0.10157608769830284,0.8744716799879915,-0.13977468780074367,-0.13977468780074367,0.2897820267826493,-0.04239342030431858,-0.13977468780074367,-0.6447419635510961,0.38234507015049096,0.2897820267826493,0.4282542060735226,-0.18889877938207092,-0.09094104587744528,0.38234507015049096,0.6987063152944422,-0.13977468780074367,-1.2356850843636273,0.6542105287099975,0.7429774213920438,7.298411945543759,-0.23831786606746352,-0.8553842121388305,3.6115632124813404,-0.23831786606746352,0.19620224214011292,1.1317712009042973,0.005872513874080369,0.4282542060735226,0.053860976884978005,-0.23831786606746352,0.6987063152944422,2.132393733047149,1.1317712009042973,-0.5412682933157936,0.4739196680085796,-0.09094104587744528,0.24312104666747653,-0.28803660939734893,-0.09094104587744528,-0.28803660939734893,0.10157608769830284,-0.18889877938207092,0.7429774213920438,2.969090607110795,-0.3380597911426015,0.3361888423900969,0.7429774213920438,-0.23831786606746352,0.10157608769830284 3367 Lipid localization 25 76 2.2859118501057414 0.022259416049629 O43772,Q6IAA8,P61916,O95674,Q8WTV0,O15260,P11166,Q14108,Q99720,Q96GC9,Q9NZJ7,P28288,P07814,Q9BUR5,Q86Y82,Q9H4L5,P35610,Q9BQE5,P23786,Q9H6V9,Q9UHB6,P35790,P04062,P30536,O15118 Processes and pathways GO Biological process msigdb_gobp 2,266,149,385,25,379,388,164,43,174,315,428,425,198,196,341,429,218,82,219,507,213,99,113,125 1868,2439,3096,125,379,2,722,1091,2773,996,887,385,1470,2449,99,1882,2168,468,3327,425,2451,388,521,1889,1110,1607,82,428,1900,113,589,2188,429,213,909,828,149,746,2068,2352,2984,3268,2986,164,2621,1145,1534,266,1271,196,3184,3245,25,2254,174,1175,43,218,1697,198,2532,1296,2270,2535,341,219,3006,315,702,1191,507,705,2283,3342,3289,871 -0.13977468780074367,-0.3380597911426015,-0.8022645150247569,1.381940746478781,0.6094870655900769,8.462226464311355,0.3361888423900969,0.14902186735214557,-0.4899972174116964,0.19620224214011292,0.24312104666747653,0.6094870655900769,0.005872513874080369,-0.3380597911426015,1.6254733747117993,-0.13977468780074367,-0.23831786606746352,0.5193447980380466,-1.9803639244210636,0.5645328647779381,-0.3380597911426015,0.6094870655900769,0.4739196680085796,-0.13977468780074367,0.14902186735214557,-0.04239342030431858,1.7843606013886042,0.5645328647779381,-0.13977468780074367,1.463832977402664,0.4282542060735226,-0.23831786606746352,0.5645328647779381,0.961063282020524,0.24312104666747653,0.2897820267826493,1.257715066848026,0.3361888423900969,-0.18889877938207092,-0.28803660939734893,-0.6447419635510961,-1.2912106707426125,-0.6447419635510961,1.1739472326847418,-0.388392317630512,0.14902186735214557,0.005872513874080369,0.8308572620954069,0.10157608769830284,1.046822951105993,-0.9625354940644615,-1.1804567452748522,3.6115632124813404,-0.23831786606746352,1.1317712009042973,0.14902186735214557,2.8638632384419833,0.961063282020524,-0.04239342030431858,1.046822951105993,-0.3380597911426015,0.10157608769830284,-0.23831786606746352,-0.3380597911426015,0.6987063152944422,0.961063282020524,-0.6447419635510961,0.7429774213920438,0.38234507015049096,0.14902186735214557,0.5193447980380466,0.38234507015049096,-0.23831786606746352,-2.340455914597067,-1.403149751562867,0.2897820267826493 3367 Phospholipid metabolism 11 52 2.2831450814386427 0.022421823809601 Q96N66,Q8NCC3,Q8IV08,Q9NPH0,Q8N2A8,Q9NQZ5,Q9UG56,Q92604,Q8N9F7,P42356,P35790 Processes and pathways Reactome Pathways msigdb_reactome 337,4,37,38,101,415,316,172,307,239,213 873,807,1199,2673,2157,385,1470,1003,2321,522,213,1233,239,1359,1911,909,2347,1369,1636,1926,665,2226,835,606,1812,1945,37,3258,101,616,307,1278,4,2246,3136,2249,172,337,2399,2889,555,2117,963,2402,1296,2123,2654,38,415,2543,316,1312 0.24312104666747653,0.2897820267826493,0.10157608769830284,-0.43903817143719953,-0.23831786606746352,0.6094870655900769,0.005872513874080369,0.19620224214011292,-0.28803660939734893,0.4739196680085796,0.961063282020524,0.10157608769830284,0.8744716799879915,0.053860976884978005,-0.13977468780074367,0.24312104666747653,-0.28803660939734893,0.053860976884978005,-0.04239342030431858,-0.13977468780074367,0.38234507015049096,-0.23831786606746352,0.2897820267826493,0.4282542060735226,-0.09094104587744528,-0.13977468780074367,2.969090607110795,-1.2356850843636273,1.6254733747117993,0.4282542060735226,0.7429774213920438,0.10157608769830284,7.298411945543759,-0.23831786606746352,-0.8553842121388305,-0.23831786606746352,1.1317712009042973,0.6987063152944422,-0.28803660939734893,-0.5412682933157936,0.4739196680085796,-0.18889877938207092,0.24312104666747653,-0.28803660939734893,0.10157608769830284,-0.18889877938207092,-0.388392317630512,2.969090607110795,0.6094870655900769,-0.3380597911426015,0.7429774213920438,0.10157608769830284 3367 Inorganic anion transport 9 20 2.280035248130961 0.0226055980237269 P51798,Q9UHG3,Q9Y696,P21796,Q9C0H2,P30536,Q00325,P45880,Q6N075 Processes and pathways GO Biological process msigdb_gobp 475,32,237,100,145,113,478,56,363 2295,1201,2451,2849,100,113,56,475,2207,2208,478,533,1033,363,145,1561,1998,32,980,237 -0.28803660939734893,0.10157608769830284,-0.3380597911426015,-0.5412682933157936,1.6254733747117993,1.463832977402664,2.394640025697565,0.5193447980380466,-0.23831786606746352,-0.23831786606746352,0.5193447980380466,0.4739196680085796,0.19620224214011292,0.6542105287099975,1.2993115136492674,0.005872513874080369,-0.13977468780074367,3.073237531524794,0.24312104666747653,0.9178727874245445 3367 Agitation 6 33 2.264334630042943 0.0235535412041774 Q15165,P42858,P04062,P05067,P35637,P42892 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,392,99,190,326,63 880,995,727,99,190,1103,1221,1222,2178,429,326,392,63,2336,652,1243,1624,2345,2346,2223,1513,603,1648,1650,2622,1,2090,2379,1399,621,960,2951,1290 0.24312104666747653,0.19620224214011292,0.3361888423900969,1.6254733747117993,1.046822951105993,0.14902186735214557,0.10157608769830284,0.10157608769830284,-0.23831786606746352,0.5645328647779381,0.6987063152944422,0.6094870655900769,2.132393733047149,-0.28803660939734893,0.38234507015049096,0.10157608769830284,-0.04239342030431858,-0.28803660939734893,-0.28803660939734893,-0.23831786606746352,0.005872513874080369,0.4282542060735226,-0.04239342030431858,-0.04239342030431858,-0.388392317630512,9.185425981910969,-0.18889877938207092,-0.28803660939734893,0.053860976884978005,0.4282542060735226,0.24312104666747653,-0.5928502525010018,0.10157608769830284 3367 Cdt1 association with the cdc6 orc origin complex 9 39 2.2554126529360405 0.0241074392744877 P60900,P28074,P20618,P49721,Q99741,P49720,P28072,Q9UBD5,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,498,354,52,221,283 1319,2436,2437,2567,875,1586,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,498,221,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,0.961063282020524,0.4282542060735226,-0.28803660939734893 3367 Azurophil granule membrane 9 22 2.2478587302693573 0.0245851994805561 P42785,P27105,Q6IAA8,Q9NZJ7,O95721,P07602,P51148,O15260,P13473 Localization GO Cellular component msigdb_gocc 3,104,266,315,228,468,298,379,389 458,379,2157,880,228,468,2318,3025,389,104,1620,3,298,1377,266,2246,683,956,2117,2898,315,702 0.5193447980380466,0.6094870655900769,-0.23831786606746352,0.24312104666747653,0.9178727874245445,0.5193447980380466,-0.28803660939734893,-0.6969423099361801,0.6094870655900769,1.5450050959353323,-0.04239342030431858,7.767211111294991,0.7429774213920438,0.053860976884978005,0.8308572620954069,-0.23831786606746352,0.38234507015049096,0.24312104666747653,-0.18889877938207092,-0.5412682933157936,0.7429774213920438,0.38234507015049096 3367 Proteasome 6 35 2.24318919212304 0.0248846169557195 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways KEGG Pathways msigdb_kegg 128,35,192,10,52,283 1319,2436,2437,2567,875,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Hedgehog ligand biogenesis 7 38 2.240855349567622 0.0250354462933573 P60900,P28074,P20618,P49721,P07237,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,323,52,283 1319,2436,2437,2567,875,2846,323,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,2346,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.6987063152944422,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Intrinsic component of mitochondrial inner membrane 12 28 2.2378217391509607 0.0252326821736681 Q9NX63,Q9HC21,Q9UG56,Q6UXV4,O60830,O14925,Q99595,Q00325,Q13505,Q5XKP0,Q9Y2R0,Q9BUR5 Localization GO Cellular component msigdb_gocc 274,413,316,364,12,420,18,478,26,194,157,198 420,3351,12,3100,884,1880,2595,478,26,483,1809,2370,1812,194,364,1952,18,198,630,1438,1439,413,1993,274,316,157,3012,801 0.5645328647779381,-2.962986316850552,5.531143228715627,-0.8022645150247569,0.24312104666747653,-0.13977468780074367,-0.388392317630512,0.5193447980380466,3.578720683939666,0.5193447980380466,-0.09094104587744528,-0.28803660939734893,-0.09094104587744528,1.046822951105993,0.6542105287099975,-0.13977468780074367,4.731666431481315,1.046822951105993,0.4282542060735226,0.053860976884978005,0.053860976884978005,0.6094870655900769,-0.13977468780074367,0.8308572620954069,0.7429774213920438,1.257715066848026,-0.6447419635510961,0.3361888423900969 3367 Deubiquitination 19 100 2.233338879408672 0.0255266054570277 P60900,P49721,Q9NWV8,Q9UPU5,Q15018,O94966,Q70CQ2,P61289,P28074,Q9NXR7,P28072,P45880,P20618,Q13309,Q99496,P21796,P49720,Q96K76,Q8TAF3 Processes and pathways Reactome Pathways msigdb_reactome 128,10,417,16,17,383,287,283,35,452,52,56,192,232,369,100,354,254,251 1319,2436,2437,2567,2440,1088,875,3123,2766,2846,1097,383,888,1594,997,1475,728,1343,192,100,2458,2179,2041,1895,1771,647,52,35,2193,590,2197,56,2599,1011,354,10,2203,1244,740,1782,3253,2785,2699,2346,128,283,1504,2609,2065,599,1792,3229,3194,1797,232,749,1380,1258,2496,750,2228,481,1524,17,2713,2802,1154,1535,1155,287,2382,1405,1162,679,251,2394,952,2252,851,254,1690,2824,2258,369,1840,2406,2539,417,452,2959,638,2426,457,16,2836,980,573,2150,3250,2755 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.3380597911426015,0.14902186735214557,0.24312104666747653,-0.8553842121388305,-0.4899972174116964,-0.5412682933157936,0.14902186735214557,0.6094870655900769,0.24312104666747653,-0.04239342030431858,0.19620224214011292,0.005872513874080369,0.3361888423900969,0.053860976884978005,1.046822951105993,1.6254733747117993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,0.4282542060735226,-0.23831786606746352,2.394640025697565,-0.388392317630512,0.19620224214011292,0.6542105287099975,6.0439644005275905,-0.23831786606746352,0.10157608769830284,0.3361888423900969,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.4282542060735226,-0.09094104587744528,-1.1255266262233685,-1.0165649980725264,-0.09094104587744528,0.9178727874245445,0.3361888423900969,0.053860976884978005,0.10157608769830284,-0.3380597911426015,0.3361888423900969,-0.23831786606746352,0.5193447980380466,0.005872513874080369,4.96585588586802,-0.43903817143719953,-0.4899972174116964,0.14902186735214557,0.005872513874080369,0.14902186735214557,0.7870267798407822,-0.28803660939734893,0.053860976884978005,0.14902186735214557,0.38234507015049096,0.8744716799879915,-0.28803660939734893,0.24312104666747653,-0.23831786606746352,0.2897820267826493,0.8744716799879915,-0.04239342030431858,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,-0.09094104587744528,-0.28803660939734893,-0.3380597911426015,0.6094870655900769,0.5645328647779381,-0.5928502525010018,0.4282542060735226,-0.28803660939734893,0.5645328647779381,5.023653846020728,-0.4899972174116964,0.24312104666747653,0.4739196680085796,-0.18889877938207092,-1.1804567452748522,-0.43903817143719953 3367 SNARE protein 7 8 2.2290354281555698 0.0258115476295632 Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 196,276,177,228,114,505,396 276,516,228,114,396,196,505,177 0.7870267798407822,0.4739196680085796,0.9178727874245445,1.463832977402664,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973 3367 SNARE protein 7 8 2.2290354281555698 0.0258115476295632 Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q9P2W9,Q13190 Functions Panther Protein class panther_protein_class 196,276,177,228,114,505,396 276,516,228,114,396,196,505,177 0.7870267798407822,0.4739196680085796,0.9178727874245445,1.463832977402664,0.6094870655900769,1.046822951105993,0.5193447980380466,1.1317712009042973 3367 Proteasome complex 9 49 2.228853804027769 0.0258236336678003 P60900,O43396,P28074,Q9BRP4,P20618,Q5VYK3,P49721,P28072,P61289 Localization GO Cellular component msigdb_gocc 128,91,35,370,192,41,10,52,283 1319,2436,2437,2567,875,91,2846,2166,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,1782,3253,2785,2699,2346,128,283,1504,2609,2065,1928,1792,1797,481,1524,484,2802,41,2634,2824,2258,370,638,2426,2755 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,1.6654484983059537,-0.5412682933157936,-0.23831786606746352,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.5193447980380466,-0.4899972174116964,2.899060884241353,-0.388392317630512,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,0.4282542060735226,-0.28803660939734893,-0.43903817143719953 3367 Abc family proteins mediated transport 7 47 2.2266797605317707 0.0259686840411537 P60900,P28074,P20618,Q9NRK6,P49721,Q9BUN8,P28072 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,207,10,80,52 1319,2436,2437,2567,875,2910,2846,885,2031,2451,1343,2040,192,2458,2179,2041,1895,1771,647,52,35,428,2193,2197,1011,354,10,1244,2699,2346,530,128,283,1504,2609,2065,1792,1797,481,1524,1279,2824,2258,80,207,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5928502525010018,-0.5412682933157936,0.24312104666747653,-0.18889877938207092,-0.3380597911426015,0.053860976884978005,-0.18889877938207092,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,0.5645328647779381,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,-0.28803660939734893,0.4739196680085796,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.10157608769830284,-0.4899972174116964,-0.23831786606746352,1.8628092769514064,1.004045806677848,0.4282542060735226,-0.28803660939734893 3367 Dna replication 24 88 2.2256103227905606 0.026040294151965 P60900,P49721,Q9NRF9,O60684,P61289,P63208,P28074,P16104,P30260,Q9BRX5,P35250,Q9UJX6,P62805,P35251,P28072,P20618,Q99741,Q9UBD5,Q96DE5,Q9UL46,Q9Y248,Q13309,P49720,Q14997 Processes and pathways Reactome Pathways msigdb_reactome 128,10,565,382,283,394,35,158,391,444,524,317,171,296,52,192,498,221,96,638,509,232,354,481 1319,2436,2437,2567,875,1586,382,2846,1755,1479,2174,158,1343,3027,192,1229,2325,2458,2179,2041,1895,1612,1771,647,52,35,2043,391,2190,1618,2046,2859,2332,524,296,2193,2596,591,2597,2978,2197,1011,1240,1495,354,10,1496,1244,3252,2699,1247,128,283,1504,2609,2065,171,394,1792,1516,833,1797,232,3241,1934,2933,2081,481,1524,1810,96,2824,2258,498,2264,444,2742,565,221,868,1308,1999,2661,317,638,2426,509,2964 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,0.6094870655900769,-0.5412682933157936,-0.09094104587744528,0.005872513874080369,-0.23831786606746352,1.2159277397438069,0.053860976884978005,-0.6969423099361801,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.04239342030431858,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.18889877938207092,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,-0.28803660939734893,0.4739196680085796,0.7429774213920438,-0.23831786606746352,-0.388392317630512,0.4282542060735226,-0.388392317630512,-0.6447419635510961,-0.23831786606746352,0.19620224214011292,0.10157608769830284,0.005872513874080369,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-1.2356850843636273,-0.43903817143719953,0.10157608769830284,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,1.1317712009042973,0.6094870655900769,-0.09094104587744528,0.005872513874080369,0.2897820267826493,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,-0.5928502525010018,-0.18889877938207092,0.5193447980380466,0.005872513874080369,-0.09094104587744528,1.6654484983059537,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,-0.23831786606746352,0.5645328647779381,-0.43903817143719953,0.4739196680085796,0.961063282020524,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-0.388392317630512,0.7429774213920438,0.4282542060735226,-0.28803660939734893,0.5193447980380466,-0.5928502525010018 3367 Endopeptidase complex 11 56 2.213832220993375 0.0268403226828939 P60900,O43396,P28074,Q9BRP4,Q9H490,P20618,Q5VYK3,P49721,Q96S52,P28072,P61289 Localization GO Cellular component msigdb_gocc 128,91,35,370,313,192,41,10,175,52,283 1319,2436,2437,2567,875,91,2846,2848,2166,818,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,737,2197,1011,354,10,1244,1782,3253,2785,2699,2346,128,283,1504,2609,2065,1928,1792,1797,481,1524,484,2802,41,2634,1548,623,175,2824,2258,370,313,638,2426,2755 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,1.6654484983059537,-0.5412682933157936,-0.5412682933157936,-0.23831786606746352,0.2897820267826493,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,0.3361888423900969,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.5193447980380466,-0.4899972174116964,2.899060884241353,-0.388392317630512,0.005872513874080369,0.4282542060735226,1.1317712009042973,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,0.7429774213920438,0.4282542060735226,-0.28803660939734893,-0.43903817143719953 3367 Ub specific processing proteases 12 78 2.212487444530439 0.0269330027847032 P60900,Q70CQ2,P28074,Q13309,P21796,P20618,P49721,Q9UPU5,Q96K76,P28072,Q8TAF3,P45880 Processes and pathways Reactome Pathways msigdb_reactome 128,287,35,232,100,192,10,16,254,52,251,56 1319,2436,2437,2567,2440,875,3123,2766,2846,1097,383,997,728,1343,192,100,2458,2179,2041,1895,1771,647,52,35,2193,2197,56,2599,1011,354,10,1244,740,1782,2699,128,283,1504,2609,2065,1792,3229,3194,1797,232,749,1380,1258,750,2228,481,1524,2713,2802,287,1405,1162,679,251,2394,952,2252,851,254,1690,2824,2258,2539,2959,638,2426,457,16,2836,980,573,2150,3250 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.3380597911426015,0.24312104666747653,-0.8553842121388305,-0.4899972174116964,-0.5412682933157936,0.14902186735214557,0.6094870655900769,0.19620224214011292,0.3361888423900969,0.053860976884978005,1.046822951105993,1.6254733747117993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,2.394640025697565,-0.388392317630512,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,0.3361888423900969,-0.09094104587744528,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-1.1255266262233685,-1.0165649980725264,-0.09094104587744528,0.9178727874245445,0.3361888423900969,0.053860976884978005,0.10157608769830284,0.3361888423900969,-0.23831786606746352,0.5193447980380466,0.005872513874080369,-0.43903817143719953,-0.4899972174116964,0.7870267798407822,0.053860976884978005,0.14902186735214557,0.38234507015049096,0.8744716799879915,-0.28803660939734893,0.24312104666747653,-0.23831786606746352,0.2897820267826493,0.8744716799879915,-0.04239342030431858,-0.4899972174116964,-0.23831786606746352,-0.3380597911426015,-0.5928502525010018,0.4282542060735226,-0.28803660939734893,0.5645328647779381,5.023653846020728,-0.4899972174116964,0.24312104666747653,0.4739196680085796,-0.18889877938207092,-1.1804567452748522 3367 Runx1 regulates transcription of genes involved in differentiation of hscs 8 42 2.1999063222532285 0.0278135420717631 P60900,P28074,P16104,P20618,P49721,P62805,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,158,192,10,171,52,283 1319,2436,2437,2567,875,2846,158,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,2981,1244,2699,128,283,1504,2609,2065,171,3193,1792,1797,2620,481,1524,1174,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,1.2159277397438069,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,-0.6447419635510961,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,1.1317712009042973,-1.0165649980725264,-0.09094104587744528,-0.09094104587744528,-0.388392317630512,0.5193447980380466,0.005872513874080369,0.14902186735214557,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Abnormality of corneal stroma 8 17 2.1973018935104527 0.0279988925216547 O43933,P04062,O43505,P10619,Q92889,Q6P4I2,P34913,Q16625 Drugs and Diseases Human Phenotype Ontology msigdb_hp 98,99,70,61,253,123,179,301 70,98,99,61,2919,819,1108,179,353,1122,924,3195,301,123,253,795,706 2.0177872441211355,1.6254733747117993,1.6254733747117993,2.283114015588119,-0.5928502525010018,0.2897820267826493,0.14902186735214557,1.0893972532895093,0.6542105287099975,0.14902186735214557,0.24312104666747653,-1.0165649980725264,0.7429774213920438,1.422977916752635,0.8744716799879915,0.3361888423900969,0.38234507015049096 3367 Orc1 removal from chromatin 11 49 2.195492313899857 0.0281283016455073 P60900,P28074,Q13309,P20618,P49721,Q99741,P49720,P28072,Q9UBD5,P61289,P63208 Processes and pathways Reactome Pathways msigdb_reactome 128,35,232,192,10,498,354,52,221,283,394 1319,2436,2437,2567,875,1586,2846,1343,192,1229,2325,2458,2179,2041,1895,1771,647,52,35,2190,1618,2046,2193,2197,1011,354,10,1496,1244,2699,128,283,1504,2609,2065,394,1792,1797,232,3241,1934,481,1524,2824,2258,498,221,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,0.961063282020524,0.4282542060735226,-0.28803660939734893 3367 Asymmetric localization of pcp proteins 6 37 2.1756317745948786 0.0295828054346638 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,1802,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Regulation of synapse structure or activity 9 38 2.1754464913644296 0.0295966737812993 Q9UQB8,Q4V328,P05067,Q9UJX6,Q14118,P50897,Q7L576,Q9UQ16,P19022 Processes and pathways GO Biological process msigdb_gobp 0,246,190,317,263,261,305,187,294 1459,190,324,2680,1001,294,2457,1909,908,261,2346,1125,2703,1127,2350,1513,1928,3071,3229,2798,668,263,1650,2079,2624,2085,246,305,2733,960,447,1562,2832,2552,317,187,0,800 0.005872513874080369,1.046822951105993,0.6987063152944422,-0.43903817143719953,0.19620224214011292,0.7429774213920438,-0.3380597911426015,-0.13977468780074367,0.24312104666747653,0.8308572620954069,-0.28803660939734893,0.14902186735214557,-0.43903817143719953,0.14902186735214557,-0.28803660939734893,0.005872513874080369,-0.13977468780074367,-0.7494501896778172,-1.1255266262233685,-0.4899972174116964,0.38234507015049096,0.8308572620954069,-0.04239342030431858,-0.18889877938207092,-0.388392317630512,-0.18889877938207092,0.8744716799879915,0.7429774213920438,-0.43903817143719953,0.24312104666747653,0.5645328647779381,0.005872513874080369,-0.4899972174116964,-0.3380597911426015,0.7429774213920438,1.0893972532895093,9.674117275578304,0.3361888423900969 3367 Protease 21 120 2.17530883806572 0.0296069806738799 P42785,Q9UIQ6,Q70CQ2,Q5BJF2,Q9BYT8,Q9HB40,Q8NHP8,P55786,Q9NZ08,P48147,Q2T9J0,P34913,P10619,P42892,P53634,P17812,O75844,O14773,Q8TCT9,Q96K76,P67812 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 3,19,287,24,154,28,29,159,47,170,49,179,61,63,328,325,87,319,235,254,241 1731,2013,2437,2843,319,874,1202,1736,1206,87,383,888,1472,1476,1217,61,2918,1224,1761,728,818,325,1227,2687,1345,2327,2778,2328,1615,179,733,2335,737,3,63,2599,170,2340,1244,740,594,1365,328,1919,1782,159,596,1632,915,241,3332,2486,2071,665,2616,3195,2619,2873,2228,2083,1655,3076,49,2238,1659,24,402,1664,1154,2940,1535,287,2511,1819,2812,486,2991,366,29,2389,2390,235,948,1548,2393,687,2731,1831,2252,954,851,1054,254,959,1690,961,2951,1177,2262,154,785,786,28,1564,3005,701,47,2136,3145,3312,2141,19,1863,457,2432,3250,514,3012,2755,575 -0.09094104587744528,-0.18889877938207092,-0.3380597911426015,-0.5412682933157936,0.6987063152944422,0.24312104666747653,0.10157608769830284,-0.09094104587744528,0.10157608769830284,1.7052535001830216,0.6094870655900769,0.24312104666747653,0.005872513874080369,0.005872513874080369,0.10157608769830284,2.283114015588119,-0.5928502525010018,0.10157608769830284,-0.09094104587744528,0.3361888423900969,0.2897820267826493,0.6987063152944422,0.10157608769830284,-0.43903817143719953,0.053860976884978005,-0.28803660939734893,-0.4899972174116964,-0.28803660939734893,-0.04239342030431858,1.0893972532895093,0.3361888423900969,-0.28803660939734893,0.3361888423900969,7.767211111294991,2.132393733047149,-0.388392317630512,1.1317712009042973,-0.28803660939734893,0.10157608769830284,0.3361888423900969,0.4282542060735226,0.053860976884978005,0.6987063152944422,-0.13977468780074367,-0.09094104587744528,1.2159277397438069,0.4282542060735226,-0.04239342030431858,0.24312104666747653,0.8744716799879915,-2.0992610771115365,-0.3380597911426015,-0.18889877938207092,0.38234507015049096,-0.388392317630512,-1.0165649980725264,-0.388392317630512,-0.5412682933157936,-0.23831786606746352,-0.18889877938207092,-0.04239342030431858,-0.7494501896778172,2.5413946027810876,-0.23831786606746352,-0.04239342030431858,3.9345059665079796,0.6094870655900769,-0.04239342030431858,0.14902186735214557,-0.5928502525010018,0.005872513874080369,0.7870267798407822,-0.3380597911426015,-0.09094104587744528,-0.4899972174116964,0.5193447980380466,-0.6447419635510961,0.6542105287099975,3.3794741768918657,-0.28803660939734893,-0.28803660939734893,0.9178727874245445,0.24312104666747653,0.005872513874080369,-0.28803660939734893,0.38234507015049096,-0.43903817143719953,-0.09094104587744528,-0.23831786606746352,0.24312104666747653,0.2897820267826493,0.19620224214011292,0.8744716799879915,0.24312104666747653,-0.04239342030431858,0.24312104666747653,-0.5928502525010018,0.14902186735214557,-0.23831786606746352,1.257715066848026,0.3361888423900969,0.3361888423900969,3.4129471399409548,0.005872513874080369,-0.6447419635510961,0.38234507015049096,2.5777445433602932,-0.18889877938207092,-0.8553842121388305,-1.6881333429715428,-0.18889877938207092,4.4014392320994515,-0.09094104587744528,0.5645328647779381,-0.28803660939734893,-1.1804567452748522,0.5193447980380466,-0.6447419635510961,-0.43903817143719953,0.4739196680085796 3367 Cation transmembrane transporter activity 15 53 2.173253174669965 0.0297612676348657 P30825,O75964,O43772,P21283,Q9UI12,Q9HC21,O95202,Q70HW3,P56385,Q9HD20,Q9UDW1,Q00325,P36542,P21281,P61421 Functions GO Molecular function msigdb_gomf 212,33,2,588,372,413,519,45,529,51,118,478,297,121,532 2,722,584,33,519,1471,1597,1102,1334,2168,2450,890,1336,2319,2585,1000,1226,2588,2322,121,588,1347,2777,212,1615,297,1905,1492,3191,2338,2208,742,529,532,1249,478,3156,1033,755,1397,45,1952,953,3163,1693,2898,3281,1438,413,51,118,372,2006 8.462226464311355,0.3361888423900969,0.4282542060735226,3.0386401585275027,0.4739196680085796,0.005872513874080369,-0.04239342030431858,0.14902186735214557,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,0.24312104666747653,0.053860976884978005,-0.28803660939734893,-0.388392317630512,0.19620224214011292,0.10157608769830284,-0.388392317630512,-0.28803660939734893,1.422977916752635,0.4282542060735226,0.053860976884978005,-0.4899972174116964,0.961063282020524,-0.04239342030431858,0.7429774213920438,-0.13977468780074367,0.005872513874080369,-1.0165649980725264,-0.28803660939734893,-0.23831786606746352,0.3361888423900969,0.4739196680085796,0.4739196680085796,0.10157608769830284,0.5193447980380466,-0.908808220790615,0.19620224214011292,0.3361888423900969,0.053860976884978005,2.7575257190991964,-0.13977468780074367,0.24312104666747653,-0.908808220790615,-0.04239342030431858,-0.5412682933157936,-1.3470325431471153,0.053860976884978005,0.6094870655900769,2.5049104893301823,1.463832977402664,0.6542105287099975,-0.13977468780074367 3367 Alcohol binding 7 17 2.172115704728 0.0298469366951164 Q14108,P21796,P30536,P61916,P45880,O15118,Q9H4L5 Functions GO Molecular function msigdb_gomf 164,100,113,149,56,125,341 807,125,3055,885,2450,100,1607,1900,113,429,56,149,164,1145,1296,2535,341 0.2897820267826493,1.381940746478781,-0.7494501896778172,0.24312104666747653,-0.3380597911426015,1.6254733747117993,-0.04239342030431858,-0.13977468780074367,1.463832977402664,0.5645328647779381,2.394640025697565,1.257715066848026,1.1739472326847418,0.14902186735214557,0.10157608769830284,-0.3380597911426015,0.6987063152944422 3367 Target SNARE coiled-coil homology domain [IPR000727] 6 7 2.1663867321202708 0.0302816469740418 Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q13190 Sequence InterPro Domain interpro_domain 196,276,177,228,114,396 276,516,228,114,396,196,177 0.7870267798407822,0.4739196680085796,0.9178727874245445,1.463832977402664,0.6094870655900769,1.046822951105993,1.1317712009042973 3367 Cross presentation of soluble exogenous antigens endosomes 6 36 2.161450225821581 0.0306605778972102 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Degradation of axin 6 36 2.161450225821581 0.0306605778972102 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 SLC25 family of mitochondrial transporters 8 19 2.152168164775248 0.031384112014585 O43772,Q9HC21,P12236,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q00325 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 2,413,470,105,315,45,500,478 2,722,1095,1102,2585,470,1917,478,533,938,45,500,105,3281,413,315,1998,867,2012 8.462226464311355,0.3361888423900969,0.14902186735214557,0.14902186735214557,-0.388392317630512,0.5193447980380466,-0.13977468780074367,0.5193447980380466,0.4739196680085796,0.24312104666747653,2.7575257190991964,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367 3367 Mitochondrial carrier domain superfamily [IPR023395] 8 19 2.152168164775248 0.031384112014585 O43772,Q9HC21,P12236,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q00325 Sequence InterPro Superfamily interpro_homologous_superfamily 2,413,470,105,315,45,500,478 2,722,1095,1102,2585,470,1917,478,533,938,45,500,105,3281,413,315,1998,867,2012 8.462226464311355,0.3361888423900969,0.14902186735214557,0.14902186735214557,-0.388392317630512,0.5193447980380466,-0.13977468780074367,0.5193447980380466,0.4739196680085796,0.24312104666747653,2.7575257190991964,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367 3367 Mitochondrial substrate/solute carrier [IPR018108] 8 19 2.152168164775248 0.031384112014585 O43772,Q9HC21,P12236,Q9H2D1,Q9NZJ7,Q70HW3,Q9BSK2,Q00325 Sequence InterPro Repeat interpro_repeat 2,413,470,105,315,45,500,478 2,722,1095,1102,2585,470,1917,478,533,938,45,500,105,3281,413,315,1998,867,2012 8.462226464311355,0.3361888423900969,0.14902186735214557,0.14902186735214557,-0.388392317630512,0.5193447980380466,-0.13977468780074367,0.5193447980380466,0.4739196680085796,0.24312104666747653,2.7575257190991964,0.5193447980380466,1.5450050959353323,-1.3470325431471153,0.6094870655900769,0.7429774213920438,-0.13977468780074367,0.2897820267826493,-0.13977468780074367 3367 Hormone metabolic process 7 26 2.148678634835405 0.0316598834542276 O95470,Q53GQ0,P30536,Q9UBM7,O75844,Q9HB40,P42892 Processes and pathways GO Biological process msigdb_gobp 34,264,113,54,87,28,63 2571,87,34,1597,728,2037,1340,113,63,2695,2603,3240,2984,1145,1147,264,1041,308,2726,680,2396,1290,28,54,3211,2562 -0.388392317630512,1.7052535001830216,3.0039248680970876,-0.04239342030431858,0.3361888423900969,-0.18889877938207092,0.053860976884978005,1.463832977402664,2.132393733047149,-0.43903817143719953,-0.388392317630512,-1.1804567452748522,-0.6447419635510961,0.14902186735214557,0.14902186735214557,0.8308572620954069,0.19620224214011292,0.7429774213920438,-0.43903817143719953,0.38234507015049096,-0.28803660939734893,0.10157608769830284,3.4129471399409548,2.431534530000306,-1.0165649980725264,-0.3380597911426015 3367 Ventricular tachycardia 6 14 2.1444259277486557 0.031998774629363 O43772,P49748,Q99996,P23786,P19022,P04899 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,230,83,82,294,322 2,322,3224,3291,294,82,1907,1361,230,1142,616,83,412,1567 8.462226464311355,0.6987063152944422,-1.1255266262233685,-1.4595613570006674,0.7429774213920438,1.7843606013886042,-0.13977468780074367,0.053860976884978005,0.9178727874245445,0.14902186735214557,0.4282542060735226,1.7843606013886042,0.6094870655900769,0.005872513874080369 3367 Vacuolar membrane 29 116 2.144229525495247 0.0320145004316791 P42785,Q6IAA8,Q9P2R3,O75503,Q9UIQ6,P20645,Q8WTV0,O15260,P13473,O15400,Q14108,Q8IV08,Q9UNK0,Q96GC9,Q9NZJ7,Q9NXC5,P51148,P10619,Q16625,P42892,Q8N511,Q96RL7,P04062,Q9UI12,Q9Y2Q5,P27105,O95721,P21281,O15118 Localization GO Cellular component msigdb_gocc 3,266,418,134,19,23,25,379,389,276,164,37,177,174,315,451,298,61,301,63,95,216,99,372,374,104,228,121,125 1458,458,714,125,379,3265,276,2443,876,2301,2157,880,134,585,886,228,1213,99,815,2168,468,2450,890,1753,1477,1219,2318,61,426,2680,3025,389,23,121,588,1486,104,2462,2592,1905,1492,1620,2978,826,3,63,2337,298,1014,475,657,3128,1784,2787,1369,532,2213,1023,3192,920,2793,1377,3268,923,2796,606,164,1145,1033,301,266,37,1826,95,2246,1046,25,548,1547,683,3163,2525,956,1415,690,1834,174,960,216,2260,2117,2402,1182,1297,2409,2898,2736,2899,3091,2741,3006,451,315,702,2834,418,372,19,2662,3342,177,374,2560,3347,2006,1083 0.005872513874080369,0.5193447980380466,0.3361888423900969,1.381940746478781,0.6094870655900769,-1.2912106707426125,0.7870267798407822,-0.3380597911426015,0.24312104666747653,-0.28803660939734893,-0.23831786606746352,0.24312104666747653,1.3407193358749927,0.4282542060735226,0.24312104666747653,0.9178727874245445,0.10157608769830284,1.6254733747117993,0.2897820267826493,-0.23831786606746352,0.5193447980380466,-0.3380597911426015,0.24312104666747653,-0.09094104587744528,0.005872513874080369,0.10157608769830284,-0.28803660939734893,2.283114015588119,0.5645328647779381,-0.43903817143719953,-0.6969423099361801,0.6094870655900769,4.123694916854529,1.422977916752635,0.4282542060735226,0.005872513874080369,1.5450050959353323,-0.3380597911426015,-0.388392317630512,-0.13977468780074367,0.005872513874080369,-0.04239342030431858,-0.6447419635510961,0.2897820267826493,7.767211111294991,2.132393733047149,-0.28803660939734893,0.7429774213920438,0.19620224214011292,0.5193447980380466,0.38234507015049096,-0.8553842121388305,-0.09094104587744528,-0.4899972174116964,0.053860976884978005,0.4739196680085796,-0.23831786606746352,0.19620224214011292,-1.0165649980725264,0.24312104666747653,-0.4899972174116964,0.053860976884978005,-1.2912106707426125,0.24312104666747653,-0.4899972174116964,0.4282542060735226,1.1739472326847418,0.14902186735214557,0.19620224214011292,0.7429774213920438,0.8308572620954069,2.969090607110795,-0.09094104587744528,1.6654484983059537,-0.23831786606746352,0.19620224214011292,3.6115632124813404,0.4739196680085796,0.005872513874080369,0.38234507015049096,-0.908808220790615,-0.3380597911426015,0.24312104666747653,0.053860976884978005,0.38234507015049096,-0.09094104587744528,1.1317712009042973,0.24312104666747653,0.961063282020524,-0.23831786606746352,-0.18889877938207092,-0.28803660939734893,0.14902186735214557,0.10157608769830284,-0.28803660939734893,-0.5412682933157936,-0.43903817143719953,-0.5412682933157936,-0.7494501896778172,-0.43903817143719953,-0.6447419635510961,0.5645328647779381,0.7429774213920438,0.38234507015049096,-0.4899972174116964,0.6094870655900769,0.6542105287099975,4.4014392320994515,-0.388392317630512,-2.340455914597067,1.1317712009042973,0.6542105287099975,-0.3380597911426015,-2.710654339272441,-0.13977468780074367,0.19620224214011292 3367 Central nervous system cyst 13 63 2.1347618700801605 0.0327804663405284 Q6P4I2,O43933,P80404,O43505,Q15125,Q14118,Q2M1P5,Q12768,P23786,Q9UBM7,P07437,Q15031,P21281 Drugs and Diseases Human Phenotype Ontology msigdb_hp 123,98,36,70,74,263,205,144,82,54,324,286,121 1322,986,2020,70,3212,1872,98,3019,2769,519,387,324,3024,817,121,82,898,1905,733,1357,1492,2056,1245,1784,1125,1370,36,1926,144,1134,3073,263,286,74,1808,205,2240,123,2880,543,2389,1048,2524,952,1285,1687,1053,2397,1421,1692,2262,1557,1423,1845,2270,2131,54,2659,705,2963,2006,803,2565 0.053860976884978005,0.19620224214011292,-0.18889877938207092,2.0177872441211355,-1.070895711677453,-0.13977468780074367,1.6254733747117993,-0.6969423099361801,-0.4899972174116964,0.4739196680085796,0.6094870655900769,0.6987063152944422,-0.6969423099361801,0.2897820267826493,1.422977916752635,1.7843606013886042,0.24312104666747653,-0.13977468780074367,0.3361888423900969,0.053860976884978005,0.005872513874080369,-0.18889877938207092,0.10157608769830284,-0.09094104587744528,0.14902186735214557,0.053860976884978005,2.969090607110795,-0.13977468780074367,1.2993115136492674,0.14902186735214557,-0.7494501896778172,0.8308572620954069,0.7870267798407822,1.9792784396533925,-0.09094104587744528,1.004045806677848,-0.23831786606746352,1.422977916752635,-0.5412682933157936,0.4739196680085796,-0.28803660939734893,0.19620224214011292,-0.3380597911426015,0.24312104666747653,0.10157608769830284,-0.04239342030431858,0.19620224214011292,-0.28803660939734893,0.053860976884978005,-0.04239342030431858,-0.23831786606746352,0.005872513874080369,0.053860976884978005,-0.09094104587744528,-0.23831786606746352,-0.18889877938207092,2.431534530000306,-0.388392317630512,0.38234507015049096,-0.5928502525010018,-0.13977468780074367,0.3361888423900969,-0.3380597911426015 3367 Heart block 8 23 2.1334952890472865 0.0328841176981602 O43772,Q9H490,P49748,Q99996,P23786,P19022,P04899,P50402 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,313,230,83,82,294,322,214 2,1094,3190,322,998,3224,294,82,1905,1492,1361,230,214,1370,2984,3268,1932,2230,616,1168,83,412,313 8.462226464311355,0.14902186735214557,-1.0165649980725264,0.6987063152944422,0.19620224214011292,-1.1255266262233685,0.7429774213920438,1.7843606013886042,-0.13977468780074367,0.005872513874080369,0.053860976884978005,0.9178727874245445,0.961063282020524,0.053860976884978005,-0.6447419635510961,-1.2912106707426125,-0.13977468780074367,-0.23831786606746352,0.4282542060735226,0.14902186735214557,1.7843606013886042,0.6094870655900769,0.7429774213920438 3367 Pcp ce pathway 6 47 2.1321713551276225 0.0329927623783057 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,886,1213,1103,1219,1220,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,657,2699,128,283,1504,2609,2065,1787,1023,920,1792,1797,1802,481,1524,1415,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.24312104666747653,0.10157608769830284,0.14902186735214557,0.10157608769830284,0.10157608769830284,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,0.38234507015049096,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,0.19620224214011292,0.24312104666747653,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.053860976884978005,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Abnormal enchondral ossification 12 30 2.1312294294211807 0.033070245637353 Q9NUQ7,O43933,Q8NCM8,O95202,Q9UG56,Q15125,Q2M1P5,O96028,Q9UBM7,Q14739,Q5F1R6,Q96L58 Drugs and Diseases Human Phenotype Ontology msigdb_hp 130,98,543,519,316,74,205,387,54,151,247,215 2669,2673,98,1739,882,519,387,1222,2176,733,1358,530,2059,3073,151,2711,74,1938,205,247,543,773,958,1172,215,1295,130,54,316,2563 -0.43903817143719953,-0.43903817143719953,1.6254733747117993,-0.09094104587744528,0.24312104666747653,0.4739196680085796,0.6094870655900769,0.10157608769830284,-0.23831786606746352,0.3361888423900969,0.053860976884978005,0.4739196680085796,-0.18889877938207092,-0.7494501896778172,1.257715066848026,-0.43903817143719953,1.9792784396533925,-0.13977468780074367,1.004045806677848,0.8744716799879915,0.4739196680085796,0.3361888423900969,0.24312104666747653,0.14902186735214557,0.961063282020524,0.10157608769830284,1.381940746478781,2.431534530000306,0.7429774213920438,-0.3380597911426015 3367 Membrane lipid metabolic process 10 35 2.1301725276984773 0.0331573722593732 O95470,Q8NCC3,Q9H490,P04062,Q96S52,Q06136,P50897,Q96G23,Q8NBX0,Q99735 Processes and pathways GO Biological process msigdb_gobp 34,4,313,99,175,262,261,20,57,217 578,2019,3055,34,99,2314,998,3275,468,3327,2919,1889,1110,821,822,261,2352,262,2986,3195,1812,57,4,1548,623,20,175,217,3309,313,793,794,315,1302,702 0.4282542060735226,-0.18889877938207092,-0.7494501896778172,3.0039248680970876,1.6254733747117993,-0.28803660939734893,0.19620224214011292,-1.3470325431471153,0.5193447980380466,-1.9803639244210636,-0.5928502525010018,-0.13977468780074367,0.14902186735214557,0.2897820267826493,0.2897820267826493,0.8308572620954069,-0.28803660939734893,0.8308572620954069,-0.6447419635510961,-1.0165649980725264,-0.09094104587744528,2.3576060307697295,7.298411945543759,0.005872513874080369,0.4282542060735226,4.309639278406814,1.1317712009042973,0.961063282020524,-1.6305533263740417,0.7429774213920438,0.3361888423900969,0.3361888423900969,0.7429774213920438,0.10157608769830284,0.38234507015049096 3367 Auf1 hnrnp d0 binds and destabilizes mrna 6 41 2.127215709919855 0.033402164414054 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,2166,2680,1760,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1513,1792,1797,2363,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,-0.23831786606746352,-0.43903817143719953,-0.09094104587744528,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.005872513874080369,-0.09094104587744528,-0.09094104587744528,-0.28803660939734893,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Degradation of dvl 6 37 2.124798929857376 0.0336033941705424 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2492,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.3380597911426015,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Regulation of ras by gaps 6 37 2.124798929857376 0.0336033941705424 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2492,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.3380597911426015,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Endoplasmic reticulum golgi intermediate compartment membrane 12 22 2.122232040581991 0.0338182571776704 O95070,Q9BVK6,Q08379,Q96GC9,O15498,P53634,Q12907,O15260,P51572,Q8N511,Q13190,Q9Y282 Localization GO Cellular component msigdb_gocc 423,558,75,174,579,328,150,379,393,95,396,31 379,579,2969,1466,423,3176,1349,1777,1012,393,328,75,601,150,396,1263,95,174,558,1062,31,3008 0.6094870655900769,0.4282542060735226,-0.6447419635510961,0.005872513874080369,0.5645328647779381,-0.9625354940644615,0.053860976884978005,-0.09094104587744528,0.19620224214011292,0.6094870655900769,0.6987063152944422,1.9017911284204507,0.4282542060735226,1.257715066848026,0.6094870655900769,0.10157608769830284,1.6654484983059537,1.1317712009042973,0.4739196680085796,0.19620224214011292,3.2104683932450104,-0.6447419635510961 3367 Histone methylation 7 63 2.122032375034236 0.0338350194355612 P16403,P10412,P16402,Q9Y3Y2,Q9H7B4,Q9BV86,Q9Y5B6 Processes and pathways GO Biological process msigdb_gobp 191,39,109,44,14,15,90 2297,1323,1088,1089,1587,463,1876,387,3190,39,109,191,3126,1606,1348,898,590,905,1775,1624,2203,2062,3193,1134,749,2361,2618,2495,2500,2365,1936,1663,1533,1940,1156,2378,2880,1400,2813,676,1164,252,2641,2254,1419,853,1694,15,1295,2269,3280,2408,2953,14,1710,2279,456,1451,2143,44,2293,1455,90 -0.28803660939734893,0.053860976884978005,0.14902186735214557,0.14902186735214557,-0.04239342030431858,0.5193447980380466,-0.13977468780074367,0.6094870655900769,-1.0165649980725264,2.9341363071598647,1.5045080195895706,1.046822951105993,-0.8553842121388305,-0.04239342030431858,0.053860976884978005,0.24312104666747653,0.4282542060735226,0.24312104666747653,-0.09094104587744528,-0.04239342030431858,-0.23831786606746352,-0.18889877938207092,-1.0165649980725264,0.14902186735214557,0.3361888423900969,-0.28803660939734893,-0.388392317630512,-0.3380597911426015,-0.3380597911426015,-0.28803660939734893,-0.13977468780074367,-0.04239342030431858,0.005872513874080369,-0.13977468780074367,0.14902186735214557,-0.28803660939734893,-0.5412682933157936,0.053860976884978005,-0.4899972174116964,0.38234507015049096,0.14902186735214557,0.8744716799879915,-0.388392317630512,-0.23831786606746352,0.053860976884978005,0.2897820267826493,-0.04239342030431858,5.081159956656381,0.10157608769830284,-0.23831786606746352,-1.3470325431471153,-0.28803660939734893,-0.5928502525010018,5.364443360547954,-0.04239342030431858,-0.23831786606746352,0.5645328647779381,0.053860976884978005,-0.18889877938207092,2.7930967970410885,-0.23831786606746352,0.053860976884978005,1.7052535001830216 3367 Secondary alcohol metabolic process 12 43 2.120128052173258 0.033995247837689 Q15800,P04062,P05067,Q15125,Q16850,Q9BQE5,P61916,Q9UBM7,Q14739,Q8WTV0,P34913,O15118 Processes and pathways GO Biological process msigdb_gobp 193,99,190,74,76,218,149,54,151,25,179,125 125,2570,1877,885,1595,99,190,2171,2587,1340,2687,179,429,2333,2979,652,738,230,1913,1630,2867,3240,149,2068,3331,431,2986,1141,2621,151,1145,3231,74,3035,3232,1938,193,76,25,2116,218,54,507 1.381940746478781,-0.388392317630512,-0.13977468780074367,0.24312104666747653,-0.04239342030431858,1.6254733747117993,1.046822951105993,-0.23831786606746352,-0.388392317630512,0.053860976884978005,-0.43903817143719953,1.0893972532895093,0.5645328647779381,-0.28803660939734893,-0.6447419635510961,0.38234507015049096,0.3361888423900969,0.9178727874245445,-0.13977468780074367,-0.04239342030431858,-0.5412682933157936,-1.1804567452748522,1.257715066848026,-0.18889877938207092,-2.0992610771115365,0.5645328647779381,-0.6447419635510961,0.14902186735214557,-0.388392317630512,1.257715066848026,0.14902186735214557,-1.1255266262233685,1.9792784396533925,-0.6969423099361801,-1.1255266262233685,-0.13977468780074367,1.046822951105993,1.9017911284204507,3.6115632124813404,-0.18889877938207092,0.961063282020524,2.431534530000306,0.5193447980380466 3367 Inner mitochondrial membrane protein complex 12 69 2.119175520976268 0.0340756362299139 O75964,P14406,Q96CU9,O60830,P09669,Q99595,Q9UDW1,O43676,Q9P0J0,Q13505,Q5XKP0,Q9BUR5 Localization GO Cellular component msigdb_gocc 33,58,7,12,112,18,118,55,220,26,194,198 3338,1460,420,55,12,1874,1465,3100,2025,584,33,3290,2027,3102,3349,1471,1334,1336,112,2319,470,1000,58,3060,1605,2322,2323,1345,1347,2777,2590,2330,1615,1489,297,2595,3191,2338,2864,527,742,529,26,839,1530,2370,609,1812,194,364,1948,3288,1952,7,1173,18,1838,3353,198,2538,1993,1567,274,220,118,510,3012,801,1457 -2.2192938988489903,0.005872513874080369,0.5645328647779381,2.394640025697565,5.531143228715627,-0.13977468780074367,0.005872513874080369,-0.8022645150247569,-0.18889877938207092,0.4282542060735226,3.0386401585275027,-1.4595613570006674,-0.18889877938207092,-0.8022645150247569,-2.8994916636965624,0.005872513874080369,0.053860976884978005,0.053860976884978005,1.463832977402664,-0.28803660939734893,0.5193447980380466,0.19620224214011292,2.320431162427097,-0.7494501896778172,-0.04239342030431858,-0.28803660939734893,-0.28803660939734893,0.053860976884978005,0.053860976884978005,-0.4899972174116964,-0.388392317630512,-0.28803660939734893,-0.04239342030431858,0.005872513874080369,0.7429774213920438,-0.388392317630512,-1.0165649980725264,-0.28803660939734893,-0.5412682933157936,0.4739196680085796,0.3361888423900969,0.4739196680085796,3.578720683939666,0.2897820267826493,0.005872513874080369,-0.28803660939734893,0.4282542060735226,-0.09094104587744528,1.046822951105993,0.6542105287099975,-0.13977468780074367,-1.403149751562867,-0.13977468780074367,6.510373398556831,0.14902186735214557,4.731666431481315,-0.09094104587744528,-3.5466505530698798,1.046822951105993,-0.3380597911426015,-0.13977468780074367,0.005872513874080369,0.8308572620954069,0.961063282020524,1.463832977402664,0.5193447980380466,-0.6447419635510961,0.3361888423900969,0.053860976884978005 3367 Scf skp2 mediated degradation of p27 p21 8 40 2.0950522395943327 0.0361663489164705 P60900,P28074,Q13309,P20618,P49721,P49720,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,232,192,10,354,52,283 1319,2436,2437,2567,875,2846,469,1343,192,1229,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,394,1792,1797,232,3241,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.5193447980380466,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Dna replication pre initiation 13 61 2.0897007451427765 0.0366446900387835 P60900,P28074,P16104,P20618,P49721,Q99741,P49720,P62805,P28072,O60684,Q9UBD5,Q14997,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,158,192,10,498,354,171,52,382,221,481,283 1319,2436,2437,2567,875,1586,382,2846,1755,2174,158,1343,192,1229,2325,2458,2179,2041,1895,1612,1771,647,52,35,2190,1618,2046,2859,2193,2197,1011,1240,1495,354,10,1496,1244,3252,2699,1247,128,283,1504,2609,2065,171,1792,1516,1797,1934,2081,481,1524,2824,2258,498,2742,565,221,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,0.6094870655900769,-0.5412682933157936,-0.09094104587744528,-0.23831786606746352,1.2159277397438069,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.04239342030431858,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.10157608769830284,0.005872513874080369,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-1.2356850843636273,-0.43903817143719953,0.10157608769830284,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,1.1317712009042973,-0.09094104587744528,0.005872513874080369,-0.09094104587744528,-0.13977468780074367,-0.18889877938207092,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,-0.43903817143719953,0.4739196680085796,0.961063282020524,0.4282542060735226,-0.28803660939734893 3367 Protein methylation 8 74 2.086648457004812 0.0369199236320216 P16403,P10412,P16402,Q9Y3Y2,Q9H7B4,Q9BV86,O60725,Q9Y5B6 Processes and pathways GO Biological process msigdb_gobp 191,39,109,44,14,15,86,90 2297,1323,1088,1089,1587,2571,86,463,1876,387,3190,39,2850,109,191,3126,2177,1606,1348,898,590,905,1775,1624,2203,2062,3068,1507,3193,1134,749,2361,2618,2495,2500,2365,1936,2936,1663,1533,1940,2506,1156,2378,2880,1400,1941,2813,676,1164,1165,252,2641,2254,1419,853,1694,15,1295,2269,3280,2408,2953,14,2273,1710,2279,456,1451,2143,44,2293,1455,90 -0.28803660939734893,0.053860976884978005,0.14902186735214557,0.14902186735214557,-0.04239342030431858,-0.388392317630512,1.744890254278231,0.5193447980380466,-0.13977468780074367,0.6094870655900769,-1.0165649980725264,2.9341363071598647,-0.5412682933157936,1.5045080195895706,1.046822951105993,-0.8553842121388305,-0.23831786606746352,-0.04239342030431858,0.053860976884978005,0.24312104666747653,0.4282542060735226,0.24312104666747653,-0.09094104587744528,-0.04239342030431858,-0.23831786606746352,-0.18889877938207092,-0.7494501896778172,0.005872513874080369,-1.0165649980725264,0.14902186735214557,0.3361888423900969,-0.28803660939734893,-0.388392317630512,-0.3380597911426015,-0.3380597911426015,-0.28803660939734893,-0.13977468780074367,-0.5928502525010018,-0.04239342030431858,0.005872513874080369,-0.13977468780074367,-0.3380597911426015,0.14902186735214557,-0.28803660939734893,-0.5412682933157936,0.053860976884978005,-0.13977468780074367,-0.4899972174116964,0.38234507015049096,0.14902186735214557,0.14902186735214557,0.8744716799879915,-0.388392317630512,-0.23831786606746352,0.053860976884978005,0.2897820267826493,-0.04239342030431858,5.081159956656381,0.10157608769830284,-0.23831786606746352,-1.3470325431471153,-0.28803660939734893,-0.5928502525010018,5.364443360547954,-0.23831786606746352,-0.04239342030431858,-0.23831786606746352,0.5645328647779381,0.053860976884978005,-0.18889877938207092,2.7930967970410885,-0.23831786606746352,0.053860976884978005,1.7052535001830216 3367 Passive transmembrane transporter activity 6 25 2.0837856382793025 0.0371796702759839 O75964,Q9BVC6,Q9Y696,P21796,Q9C0H2,P45880 Functions GO Molecular function msigdb_gomf 33,65,237,100,145,56 2295,584,33,727,1334,2168,2450,2849,100,1347,2777,297,1492,56,2338,475,742,529,1249,1952,953,65,145,980,237 -0.28803660939734893,0.4282542060735226,3.0386401585275027,0.3361888423900969,0.053860976884978005,-0.23831786606746352,-0.3380597911426015,-0.5412682933157936,1.6254733747117993,0.053860976884978005,-0.4899972174116964,0.7429774213920438,0.005872513874080369,2.394640025697565,-0.28803660939734893,0.5193447980380466,0.3361888423900969,0.4739196680085796,0.10157608769830284,-0.13977468780074367,0.24312104666747653,2.0943433015075343,1.2993115136492674,0.24312104666747653,0.9178727874245445 3367 G1 s dna damage checkpoints 6 41 2.077455939217534 0.0377594978329784 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,1579,2567,875,2846,1470,997,1343,192,1229,2458,2179,2041,1895,1771,647,52,35,2193,3177,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.04239342030431858,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.005872513874080369,0.19620224214011292,0.053860976884978005,1.046822951105993,0.10157608769830284,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.9625354940644615,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Rac1 gtpase cycle 11 48 2.0604080130350644 0.0393595515082776 Q9UQB8,Q9Y2I1,Q96F07,Q6IAA8,O75962,Q13459,Q7L576,Q14739,Q9NRY4,P50402,Q14185 Processes and pathways Reactome Pathways msigdb_reactome 0,132,269,266,352,330,305,151,156,214,300 3015,2566,579,352,1472,1751,2582,1116,736,3251,1118,214,1014,2784,1125,1787,2482,358,2617,1796,330,3075,300,2497,151,755,3242,1034,1268,266,305,1404,487,2395,269,1053,2995,1976,1697,1561,2740,156,2277,0,869,132,2429,800 -0.6969423099361801,-0.388392317630512,0.4282542060735226,0.6542105287099975,0.005872513874080369,-0.09094104587744528,-0.388392317630512,0.14902186735214557,0.3361888423900969,-1.2356850843636273,0.14902186735214557,0.961063282020524,0.19620224214011292,-0.4899972174116964,0.14902186735214557,-0.09094104587744528,-0.3380597911426015,0.6542105287099975,-0.388392317630512,-0.09094104587744528,0.6987063152944422,-0.7494501896778172,0.7429774213920438,-0.3380597911426015,1.257715066848026,0.3361888423900969,-1.1804567452748522,0.19620224214011292,0.10157608769830284,0.8308572620954069,0.7429774213920438,0.053860976884978005,0.5193447980380466,-0.28803660939734893,0.8308572620954069,0.19620224214011292,-0.6447419635510961,-0.13977468780074367,-0.04239342030431858,0.005872513874080369,-0.43903817143719953,1.257715066848026,-0.23831786606746352,9.674117275578304,0.2897820267826493,1.381940746478781,-0.28803660939734893,0.3361888423900969 3367 Cerebellar cyst 9 47 2.054750454731721 0.0399031138972132 O43505,Q15125,Q14118,Q2M1P5,Q12768,P23786,Q9UBM7,Q6P4I2,P21281 Drugs and Diseases Human Phenotype Ontology msigdb_hp 70,74,263,205,144,82,54,123,121 1322,986,2020,70,3212,1872,3019,2769,324,3024,121,82,1905,733,1492,2056,1784,1125,1370,144,1134,263,74,1808,205,2240,123,2880,543,2389,1048,2524,952,1285,1687,1053,1692,2262,1423,1845,2270,2131,54,705,2006,803,2565 0.053860976884978005,0.19620224214011292,-0.18889877938207092,2.0177872441211355,-1.070895711677453,-0.13977468780074367,-0.6969423099361801,-0.4899972174116964,0.6987063152944422,-0.6969423099361801,1.422977916752635,1.7843606013886042,-0.13977468780074367,0.3361888423900969,0.005872513874080369,-0.18889877938207092,-0.09094104587744528,0.14902186735214557,0.053860976884978005,1.2993115136492674,0.14902186735214557,0.8308572620954069,1.9792784396533925,-0.09094104587744528,1.004045806677848,-0.23831786606746352,1.422977916752635,-0.5412682933157936,0.4739196680085796,-0.28803660939734893,0.19620224214011292,-0.3380597911426015,0.24312104666747653,0.10157608769830284,-0.04239342030431858,0.19620224214011292,-0.04239342030431858,-0.23831786606746352,0.053860976884978005,-0.09094104587744528,-0.23831786606746352,-0.18889877938207092,2.431534530000306,0.38234507015049096,-0.13977468780074367,0.3361888423900969,-0.3380597911426015 3367 Abnormality of the skull base 17 68 2.045114598825545 0.0408435613386837 P80404,Q9H490,O43505,P49748,Q15125,P21281,Q9UJX6,Q14118,Q2M1P5,Q12768,P23786,Q9UBM7,Q14739,P19022,Q6P4I2,Q9NPL8,Q96L58 Drugs and Diseases Human Phenotype Ontology msigdb_hp 36,313,70,230,74,121,317,263,205,144,82,54,151,294,123,155,215 983,3016,1322,986,2020,3123,70,3212,1872,3019,2769,2158,1739,1210,324,294,121,2176,82,1112,1905,1492,1911,3358,230,2472,2056,1122,1784,1125,1370,1787,36,665,144,1134,924,263,151,74,1808,205,2240,123,2880,1668,543,2389,1048,2524,952,1285,1687,215,853,1692,2262,1295,1845,2270,313,155,54,2659,705,317,2006,2565 0.19620224214011292,-0.6969423099361801,0.053860976884978005,0.19620224214011292,-0.18889877938207092,-0.8553842121388305,2.0177872441211355,-1.070895711677453,-0.13977468780074367,-0.6969423099361801,-0.4899972174116964,-0.23831786606746352,-0.09094104587744528,0.10157608769830284,0.6987063152944422,0.7429774213920438,1.422977916752635,-0.23831786606746352,1.7843606013886042,0.14902186735214557,-0.13977468780074367,0.005872513874080369,-0.13977468780074367,-5.28006847826639,0.9178727874245445,-0.3380597911426015,-0.18889877938207092,0.14902186735214557,-0.09094104587744528,0.14902186735214557,0.053860976884978005,-0.09094104587744528,2.969090607110795,0.38234507015049096,1.2993115136492674,0.14902186735214557,0.24312104666747653,0.8308572620954069,1.257715066848026,1.9792784396533925,-0.09094104587744528,1.004045806677848,-0.23831786606746352,1.422977916752635,-0.5412682933157936,-0.04239342030431858,0.4739196680085796,-0.28803660939734893,0.19620224214011292,-0.3380597911426015,0.24312104666747653,0.10157608769830284,-0.04239342030431858,0.961063282020524,0.2897820267826493,-0.04239342030431858,-0.23831786606746352,0.10157608769830284,-0.09094104587744528,-0.23831786606746352,0.7429774213920438,1.257715066848026,2.431534530000306,-0.388392317630512,0.38234507015049096,0.7429774213920438,-0.13977468780074367,-0.3380597911426015 3367 Organic acid transport 9 40 2.040705793720353 0.0412800791429106 P30825,O43772,P80404,Q9H2D1,O75915,P23786,P28288,O60831,P11166 Processes and pathways GO Biological process msigdb_gobp 212,2,36,105,226,82,428,320,388 2016,3096,2,722,320,1095,226,1880,887,2449,1882,1751,425,2451,890,388,521,82,428,1900,212,589,2188,2978,828,1917,911,2208,36,533,2986,753,1654,755,1271,105,3281,1438,1998,867 -0.18889877938207092,-0.8022645150247569,8.462226464311355,0.3361888423900969,0.6987063152944422,0.14902186735214557,0.9178727874245445,-0.13977468780074367,0.24312104666747653,-0.3380597911426015,-0.13977468780074367,-0.09094104587744528,0.5645328647779381,-0.3380597911426015,0.24312104666747653,0.6094870655900769,0.4739196680085796,1.7843606013886042,0.5645328647779381,-0.13977468780074367,0.961063282020524,0.4282542060735226,-0.23831786606746352,-0.6447419635510961,0.2897820267826493,-0.13977468780074367,0.24312104666747653,-0.23831786606746352,2.969090607110795,0.4739196680085796,-0.6447419635510961,0.3361888423900969,-0.04239342030431858,0.3361888423900969,0.10157608769830284,1.5450050959353323,-1.3470325431471153,0.053860976884978005,-0.13977468780074367,0.2897820267826493 3367 Long chain fatty acid transport 6 13 2.037336155671014 0.0416163669921658 O43772,P14174,P23786,P28288,P11166,P07814 Processes and pathways GO Biological process msigdb_gobp 2,521,82,428,388,425 3096,2,887,1882,425,388,521,82,428,589,2188,828,1271 -0.8022645150247569,8.462226464311355,0.24312104666747653,-0.13977468780074367,0.5645328647779381,0.6094870655900769,0.4739196680085796,1.7843606013886042,0.5645328647779381,0.4282542060735226,-0.23831786606746352,0.2897820267826493,0.10157608769830284 3367 Peptidase complex 12 65 2.037145162163506 0.0416354972896948 P60900,O43396,P28074,Q9BRP4,Q9H490,P20618,Q5VYK3,P49721,Q96S52,P28072,P61289,P67812 Localization GO Cellular component msigdb_gocc 128,91,35,370,313,192,41,10,175,52,283,241 1319,2436,2437,2567,875,91,2846,2848,2166,818,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,737,2197,1011,354,10,827,1244,1782,3253,2785,2699,2346,128,596,283,1504,2609,2065,241,1928,1792,1797,481,1387,1524,484,2802,41,2634,1548,623,1969,175,2824,2258,370,313,638,2426,457,2150,3012,2755,711 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,1.6654484983059537,-0.5412682933157936,-0.5412682933157936,-0.23831786606746352,0.2897820267826493,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,0.3361888423900969,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.2897820267826493,0.10157608769830284,-0.09094104587744528,-1.2356850843636273,-0.4899972174116964,-0.43903817143719953,-0.28803660939734893,1.381940746478781,0.4282542060735226,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.8744716799879915,-0.13977468780074367,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.053860976884978005,0.005872513874080369,0.5193447980380466,-0.4899972174116964,2.899060884241353,-0.388392317630512,0.005872513874080369,0.4282542060735226,-0.13977468780074367,1.1317712009042973,-0.4899972174116964,-0.23831786606746352,0.6542105287099975,0.7429774213920438,0.4282542060735226,-0.28803660939734893,0.5645328647779381,-0.18889877938207092,-0.6447419635510961,-0.43903817143719953,0.38234507015049096 3367 Stabilization of p53 6 39 2.02867491292351 0.0424914127545454 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1470,997,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,3177,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.005872513874080369,0.19620224214011292,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.9625354940644615,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Abnormality of the mitochondrion 11 88 2.028221946716977 0.0425376009696485 O43772,Q4G0N4,Q96CU9,P49748,Q70HW3,O75648,P23786,O43676,Q9P0J0,Q9NPL8,Q9Y2R0 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,166,7,230,45,147,82,55,220,155,157 3338,1320,1460,55,3222,2,1874,1465,2025,147,884,3102,3349,1471,3024,2916,1756,817,3313,2585,1000,2173,1605,2322,2323,2687,82,1348,2590,1772,2330,326,2048,2692,1233,1005,1360,1361,230,2864,527,1628,2206,1366,2346,2928,478,603,1648,2799,1809,1530,840,609,166,245,1266,1662,1396,45,3318,2884,1948,488,2391,7,849,1421,553,1290,556,1425,2897,2412,2537,155,1567,1190,220,2657,1998,2905,2428,157,513,3012,2434,1457 -2.2192938988489903,0.053860976884978005,0.005872513874080369,2.394640025697565,-1.1255266262233685,8.462226464311355,-0.13977468780074367,0.005872513874080369,-0.18889877938207092,1.257715066848026,0.24312104666747653,-0.8022645150247569,-2.8994916636965624,0.005872513874080369,-0.6969423099361801,-0.5928502525010018,-0.09094104587744528,0.2897820267826493,-1.7460032195660424,-0.388392317630512,0.19620224214011292,-0.23831786606746352,-0.04239342030431858,-0.28803660939734893,-0.28803660939734893,-0.43903817143719953,1.7843606013886042,0.053860976884978005,-0.388392317630512,-0.09094104587744528,-0.28803660939734893,0.6987063152944422,-0.18889877938207092,-0.43903817143719953,0.10157608769830284,0.19620224214011292,0.053860976884978005,0.053860976884978005,0.9178727874245445,-0.5412682933157936,0.4739196680085796,-0.04239342030431858,-0.23831786606746352,0.053860976884978005,-0.28803660939734893,-0.5928502525010018,0.5193447980380466,0.4282542060735226,-0.04239342030431858,-0.4899972174116964,-0.09094104587744528,0.005872513874080369,0.2897820267826493,0.4282542060735226,1.1739472326847418,0.8744716799879915,0.10157608769830284,-0.04239342030431858,0.053860976884978005,2.7575257190991964,-1.8041620789267372,-0.5412682933157936,-0.13977468780074367,0.5193447980380466,-0.28803660939734893,6.510373398556831,0.2897820267826493,0.053860976884978005,0.4739196680085796,0.10157608769830284,0.4739196680085796,0.053860976884978005,-0.5412682933157936,-0.28803660939734893,-0.3380597911426015,1.257715066848026,0.005872513874080369,0.14902186735214557,0.961063282020524,-0.388392317630512,-0.13977468780074367,-0.5412682933157936,-0.28803660939734893,1.257715066848026,0.5193447980380466,-0.6447419635510961,-0.28803660939734893,0.053860976884978005 3367 Synthesis of dna 21 83 2.0273796257579986 0.0426236039415857 P60900,P49721,Q9NRF9,P61289,P63208,P28074,P30260,Q9BRX5,P35250,Q9UJX6,P35251,P28072,P20618,Q99741,Q9UBD5,Q96DE5,Q9UL46,Q9Y248,Q13309,P49720,Q14997 Processes and pathways Reactome Pathways msigdb_reactome 128,10,565,283,394,35,391,444,524,317,296,52,192,498,221,96,638,509,232,354,481 1319,2436,2437,2567,875,1586,2846,1755,1479,2174,1343,3027,192,1229,2325,2458,2179,2041,1895,1612,1771,647,52,35,2043,391,2190,1618,2046,2859,2332,524,296,2193,2596,591,2597,2978,2197,1011,1240,1495,354,10,1496,1244,2699,1247,128,283,1504,2609,2065,394,1792,1516,833,1797,232,3241,1934,2933,481,1524,1810,96,2824,2258,498,2264,444,2742,565,221,868,1308,1999,2661,317,638,2426,509,2964 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.04239342030431858,-0.5412682933157936,-0.09094104587744528,0.005872513874080369,-0.23831786606746352,0.053860976884978005,-0.6969423099361801,1.046822951105993,0.10157608769830284,-0.28803660939734893,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.04239342030431858,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.18889877938207092,0.6094870655900769,-0.23831786606746352,-0.04239342030431858,-0.18889877938207092,-0.5412682933157936,-0.28803660939734893,0.4739196680085796,0.7429774213920438,-0.23831786606746352,-0.388392317630512,0.4282542060735226,-0.388392317630512,-0.6447419635510961,-0.23831786606746352,0.19620224214011292,0.10157608769830284,0.005872513874080369,0.6542105287099975,6.0439644005275905,0.005872513874080369,0.10157608769830284,-0.43903817143719953,0.10157608769830284,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,-0.09094104587744528,0.005872513874080369,0.2897820267826493,-0.09094104587744528,0.9178727874245445,-1.1804567452748522,-0.13977468780074367,-0.5928502525010018,0.5193447980380466,0.005872513874080369,-0.09094104587744528,1.6654484983059537,-0.4899972174116964,-0.23831786606746352,0.5193447980380466,-0.23831786606746352,0.5645328647779381,-0.43903817143719953,0.4739196680085796,0.961063282020524,0.2897820267826493,0.10157608769830284,-0.13977468780074367,-0.388392317630512,0.7429774213920438,0.4282542060735226,-0.28803660939734893,0.5193447980380466,-0.5928502525010018 3367 Regulation of runx3 expression and activity 6 37 2.025737500527214 0.0427916916212207 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,3177,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,2620,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.9625354940644615,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.388392317630512,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Organic acid transmembrane transport 7 26 2.025405533716832 0.0428257397021729 P30825,O43772,Q9H2D1,O75915,P23786,O60831,P11166 Processes and pathways GO Biological process msigdb_gobp 212,2,105,226,82,320,388 2,320,1095,226,1880,1751,2451,890,388,82,428,212,589,2188,2978,828,1917,911,533,753,755,105,3281,1438,1998,867 8.462226464311355,0.6987063152944422,0.14902186735214557,0.9178727874245445,-0.13977468780074367,-0.09094104587744528,-0.3380597911426015,0.24312104666747653,0.6094870655900769,1.7843606013886042,0.5645328647779381,0.961063282020524,0.4282542060735226,-0.23831786606746352,-0.6447419635510961,0.2897820267826493,-0.13977468780074367,0.24312104666747653,0.4739196680085796,0.3361888423900969,0.3361888423900969,1.5450050959353323,-1.3470325431471153,0.053860976884978005,-0.13977468780074367,0.2897820267826493 3367 Adult behavior 6 18 1.9981865267835528 0.045696441680433 P80404,P05067,P28289,P50897,O75844,O15118 Processes and pathways GO Biological process msigdb_gobp 36,190,102,261,87,125 1086,125,87,2678,190,1599,102,1909,2053,261,1624,36,2379,366,683,3246,1419,2951 0.14902186735214557,1.381940746478781,1.7052535001830216,-0.43903817143719953,1.046822951105993,-0.04239342030431858,1.5853262214974166,-0.13977468780074367,-0.18889877938207092,0.8308572620954069,-0.04239342030431858,2.969090607110795,-0.28803660939734893,0.6542105287099975,0.38234507015049096,-1.1804567452748522,0.053860976884978005,-0.5928502525010018 3367 Mapk6 mapk4 signaling 6 47 1.985502221310075 0.0470886232270615 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,1582,875,2846,2166,1475,1343,192,2689,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,1125,283,1504,2609,2065,1787,1792,1796,1797,481,1524,1529,3242,2824,2258,1441,2136,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,-0.04239342030431858,0.24312104666747653,-0.5412682933157936,-0.23831786606746352,0.005872513874080369,0.053860976884978005,1.046822951105993,-0.43903817143719953,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.14902186735214557,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,0.005872513874080369,-1.1804567452748522,-0.4899972174116964,-0.23831786606746352,0.053860976884978005,-0.18889877938207092,0.4282542060735226,-0.28803660939734893 3367 Ventricular arrhythmia 9 35 1.984430234083064 0.0472078983464128 O43772,Q9BTV4,P49748,Q99996,P23786,P19022,P04899,P50402,P42892 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,412,230,83,82,294,322,214,63 2,1328,1465,1744,1471,3190,322,3057,2318,2585,389,3224,3291,294,2323,82,901,2194,1907,63,1361,230,2199,214,3217,1932,1142,616,1409,1168,2525,553,83,412,1567 8.462226464311355,0.053860976884978005,0.005872513874080369,-0.09094104587744528,0.005872513874080369,-1.0165649980725264,0.6987063152944422,-0.7494501896778172,-0.28803660939734893,-0.388392317630512,0.6094870655900769,-1.1255266262233685,-1.4595613570006674,0.7429774213920438,-0.28803660939734893,1.7843606013886042,0.24312104666747653,-0.23831786606746352,-0.13977468780074367,2.132393733047149,0.053860976884978005,0.9178727874245445,-0.23831786606746352,0.961063282020524,-1.070895711677453,-0.13977468780074367,0.14902186735214557,0.4282542060735226,0.053860976884978005,0.14902186735214557,-0.3380597911426015,0.4739196680085796,1.7843606013886042,0.6094870655900769,0.005872513874080369 3367 Cellular response to hypoxia 6 39 1.983042859529598 0.0473626423201387 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,2699,128,283,1504,2609,2065,1792,1797,836,481,1524,1805,3196,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.2897820267826493,0.5193447980380466,0.005872513874080369,-0.09094104587744528,-1.0165649980725264,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Hedgehog off state 16 52 1.980354703834783 0.0476636859247787 P60900,P28074,Q8NCM8,P20618,P49721,P48729,Q9UL46,Q9Y496,Q2M1P5,P49720,P68371,P28072,P04350,Q14997,P61289,P63208 Processes and pathways Reactome Pathways msigdb_reactome 128,35,543,192,10,653,638,318,205,354,597,52,293,481,283,394 1319,2436,2437,2567,875,2846,293,1222,1338,1343,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,653,354,10,1120,1244,2699,128,283,1504,2609,2065,394,597,1792,1797,1139,3241,1382,481,1524,205,543,1174,2824,2258,2122,3187,638,2426,318 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.7429774213920438,0.10157608769830284,0.053860976884978005,0.053860976884978005,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.38234507015049096,0.6542105287099975,6.0439644005275905,0.14902186735214557,0.10157608769830284,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,0.6094870655900769,0.4282542060735226,-0.09094104587744528,-0.09094104587744528,0.14902186735214557,-1.1804567452748522,0.053860976884978005,0.5193447980380466,0.005872513874080369,1.004045806677848,0.4739196680085796,0.14902186735214557,-0.4899972174116964,-0.23831786606746352,-0.18889877938207092,-0.9625354940644615,0.4282542060735226,-0.28803660939734893,0.7429774213920438 3367 Nucleosome assembly 6 34 1.979143562928072 0.0477998449631997 P16104,P16403,P10412,P16402,Q9H7B4,P62805 Processes and pathways GO Biological process msigdb_gobp 158,191,39,109,14,171 2023,463,3022,889,39,158,109,191,1768,895,2046,1775,2863,1496,658,171,1789,3034,2617,233,3130,1813,1962,1169,1049,1837,1979,1059,629,14,565,3143,2417,703 -0.18889877938207092,0.5193447980380466,-0.6969423099361801,0.24312104666747653,2.9341363071598647,1.2159277397438069,1.5045080195895706,1.046822951105993,-0.09094104587744528,0.24312104666747653,-0.18889877938207092,-0.09094104587744528,-0.5412682933157936,0.005872513874080369,0.38234507015049096,1.1317712009042973,-0.09094104587744528,-0.6969423099361801,-0.388392317630512,0.9178727874245445,-0.8553842121388305,-0.09094104587744528,-0.13977468780074367,0.14902186735214557,0.19620224214011292,-0.09094104587744528,-0.13977468780074367,0.19620224214011292,0.4282542060735226,5.364443360547954,0.4739196680085796,-0.8553842121388305,-0.28803660939734893,0.38234507015049096 3367 Coated vesicle 20 83 1.9790692084119128 0.047808214696482 Q9BVK6,Q12907,P20645,P51572,Q13190,Q9Y282,O15027,Q14108,O43752,Q5VYK3,P04439,P42892,O95070,P05067,Q08379,P53634,Q8N511,Q5VW38,O95487,P01889 Localization GO Cellular component msigdb_gocc 558,150,23,393,396,31,275,164,516,41,424,63,423,190,75,328,95,248,466,126 1458,2758,873,2670,275,876,516,2766,1205,2302,1466,886,994,423,996,466,1213,126,1472,424,190,1219,1220,1601,1337,2680,1759,522,23,3176,2192,63,2053,1777,1012,1914,2865,393,2475,1780,328,657,1498,3128,2058,1369,661,1023,920,1926,75,150,1645,396,1138,164,2080,1262,1388,1807,248,41,95,2525,1415,558,1182,2736,2899,2741,972,2278,2834,2548,3168,2552,2553,2662,31,3008,3343,870,1315 0.005872513874080369,-0.4899972174116964,0.24312104666747653,-0.43903817143719953,0.7870267798407822,0.24312104666747653,0.4739196680085796,-0.4899972174116964,0.10157608769830284,-0.28803660939734893,0.005872513874080369,0.24312104666747653,0.19620224214011292,0.5645328647779381,0.19620224214011292,0.5193447980380466,0.10157608769830284,1.381940746478781,0.005872513874080369,0.5645328647779381,1.046822951105993,0.10157608769830284,0.10157608769830284,-0.04239342030431858,0.053860976884978005,-0.43903817143719953,-0.09094104587744528,0.4739196680085796,4.123694916854529,-0.9625354940644615,-0.23831786606746352,2.132393733047149,-0.18889877938207092,-0.09094104587744528,0.19620224214011292,-0.13977468780074367,-0.5412682933157936,0.6094870655900769,-0.3380597911426015,-0.09094104587744528,0.6987063152944422,0.38234507015049096,0.005872513874080369,-0.8553842121388305,-0.18889877938207092,0.053860976884978005,0.38234507015049096,0.19620224214011292,0.24312104666747653,-0.13977468780074367,1.9017911284204507,1.257715066848026,-0.04239342030431858,0.6094870655900769,0.14902186735214557,1.1739472326847418,-0.18889877938207092,0.10157608769830284,0.053860976884978005,-0.09094104587744528,0.8744716799879915,2.899060884241353,1.6654484983059537,-0.3380597911426015,0.053860976884978005,0.4739196680085796,0.14902186735214557,-0.43903817143719953,-0.5412682933157936,-0.43903817143719953,0.24312104666747653,-0.23831786606746352,-0.4899972174116964,-0.3380597911426015,-0.908808220790615,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,3.2104683932450104,-0.6447419635510961,-2.340455914597067,0.2897820267826493,0.10157608769830284 3367 Metabolism of polyamines 6 38 1.962973745908811 0.0496492247368172 P60900,P28074,P20618,P49721,P28072,P61289 Processes and pathways Reactome Pathways msigdb_reactome 128,35,192,10,52,283 1319,2436,2437,2567,875,2846,1343,1002,192,2458,2179,2041,1895,1771,647,52,35,2193,2197,1011,354,10,1244,3227,2699,128,283,1504,2609,2065,1792,1797,481,1524,2824,2258,638,2426 0.053860976884978005,-0.3380597911426015,-0.3380597911426015,-0.388392317630512,0.24312104666747653,-0.5412682933157936,0.053860976884978005,0.19620224214011292,1.046822951105993,-0.3380597911426015,-0.23831786606746352,-0.18889877938207092,-0.13977468780074367,-0.09094104587744528,0.38234507015049096,2.431534530000306,3.0039248680970876,-0.23831786606746352,-0.23831786606746352,0.19620224214011292,0.6542105287099975,6.0439644005275905,0.10157608769830284,-1.1255266262233685,-0.43903817143719953,1.381940746478781,0.7870267798407822,0.005872513874080369,-0.388392317630512,-0.18889877938207092,-0.09094104587744528,-0.09094104587744528,0.5193447980380466,0.005872513874080369,-0.4899972174116964,-0.23831786606746352,0.4282542060735226,-0.28803660939734893 3367 Cortical dysplasia 9 34 1.9610871080021808 0.0498688623576866 Q6P1N0,Q96N66,Q9NUQ7,Q14139,Q2M389,O43505,Q71SY5,O95721,P07437 Drugs and Diseases Human Phenotype Ontology msigdb_hp 162,337,130,432,40,70,137,228,324 1869,1577,70,1589,228,324,1217,1764,826,2471,2199,2603,2208,2795,2616,1139,2077,1382,432,40,162,2091,137,1281,2253,1970,337,496,1977,3187,130,794,2139,1194 -0.13977468780074367,-0.04239342030431858,2.0177872441211355,-0.04239342030431858,0.9178727874245445,0.6987063152944422,0.10157608769830284,-0.09094104587744528,0.2897820267826493,-0.3380597911426015,-0.23831786606746352,-0.388392317630512,-0.23831786606746352,-0.4899972174116964,-0.388392317630512,0.14902186735214557,-0.18889877938207092,0.053860976884978005,0.5645328647779381,2.899060884241353,1.2159277397438069,-0.18889877938207092,1.3407193358749927,0.10157608769830284,-0.23831786606746352,-0.13977468780074367,0.6987063152944422,0.5193447980380466,-0.13977468780074367,-0.9625354940644615,1.381940746478781,0.3361888423900969,-0.18889877938207092,0.14902186735214557 3367