term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Mitochondria 164 399 4.938044577924278 7.890980727478801e-07 P48735,P42704,P78540,O43772,Q70HW3,Q96AY3,P80404,Q9NPL8,P11310,Q9BT17,Q9UBX3,Q9BUR5,Q6GYQ0,Q9Y5L4,Q9Y6C9,Q3SXM5,O95831,P05141,P04179,Q8N983,P40939,P43304,Q10713,Q9UDX5,Q7Z2W9,Q5VT66,O96008,Q9HCC0,Q96I36,Q7L0Y3,Q6DKK2,Q6UXV4,O00411,Q4VC31,O43819,P08574,P00367,P09622,P23378,Q86Y39,Q9Y2Q9,P36776,Q00325,Q96QE5,Q6NVY1,O75306,Q6DKI1,Q9UKN8,Q8N3Z3,Q9NR28,Q00059,P56134,Q9NVH0,Q9Y277,Q9HC21,Q9BQ75,Q9H7D7,Q7L2E3,O75352,P82664,Q9H2D1,P10515,P51970,O60488,P30837,P24752,O00483,P50416,P43897,Q15031,Q92947,Q8IXI1,Q9Y3D3,Q96RQ3,P31040,Q9HA77,Q9P0J0,Q9Y394,Q7Z434,Q9H2W6,P23368,Q9BZ95,Q8IYB8,P42126,P34897,P30405,Q9H3K2,Q9BYC9,P09669,O15091,P40926,P13804,P47985,P53597,Q9BXK5,P49590,Q9BQP7,Q3ZCQ8,P13674,Q4G176,Q16891,Q4G0N4,Q9NYK5,Q9NVH1,Q9Y512,O95182,P82912,O75439,O75616,P08559,O75600,P28070,P30038,Q96A26,Q9H583,Q969Z0,Q9P015,Q5XKP0,Q96GC5,Q96EY7,Q15120,Q92667,Q8NBU5,Q96SY0,Q96RP9,Q9NRF8,Q9H845,Q9H9J2,Q9NQ29,Q9NWS8,Q9Y2Z4,Q9Y3D9,Q5T653,Q6PI48,Q8TD30,Q9NUJ1,O15382,P30044,Q56VL3,P21912,P42574,Q8NAN2,Q9NX14,Q9NXF1,O75648,O94925,P12236,Q96C36,Q8NBN7,Q8N442,Q9NX47,Q9NVV4,Q6P1L8,O95299,P10606,P13073,P53701,P55809,Q96TC7,Q9BZE1,Q9HAV7,Q9Y399,Q9Y3E5,P30084 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 1,489,495,7,10,20,21,26,29,573,580,39,556,44,45,554,51,534,533,58,539,540,547,83,78,77,75,630,98,95,94,614,86,612,587,592,103,593,595,119,122,600,606,685,678,133,677,154,151,690,147,145,166,701,164,161,162,679,156,159,179,650,172,647,169,656,167,661,660,185,761,756,213,765,203,226,777,228,222,771,218,769,252,723,720,719,260,258,716,707,722,717,240,729,282,727,280,819,267,820,818,309,840,320,322,293,302,786,787,788,291,296,297,347,353,888,357,340,891,889,339,886,883,895,894,902,899,900,901,904,905,906,377,378,884,386,851,861,373,361,363,411,420,421,393,394,397,461,458,456,474,473,452,427,429,430,436,438,510,512,514,523,524,485 2092,86,167,2731,848,1001,707,851,2531,2283,912,7,587,1462,1280,647,1725,2455,2984,2100,133,1181,156,2199,916,786,2000,1282,291,787,393,2001,1632,1004,1553,918,394,2370,293,1633,427,51,1188,75,103,2284,533,1006,1816,534,1910,2105,2288,788,592,2839,593,716,650,429,1470,1098,920,29,1009,1638,397,430,267,717,1639,2213,1286,1194,1100,361,1475,1195,2469,2682,2111,218,595,2293,2470,1382,656,1012,2222,1383,1384,296,2113,297,861,2471,1825,485,719,169,203,1477,720,2116,1015,1387,600,1201,1924,1925,722,539,723,363,489,1390,540,660,1203,1927,1928,240,3034,1,1023,1295,3359,727,1024,1648,1744,661,865,934,172,1107,1931,729,436,1297,866,1027,438,145,1838,495,21,3040,1300,159,1940,1661,302,1662,939,1575,147,606,1490,1219,3210,2239,547,2031,1303,1941,3363,2136,2908,3076,1671,2911,874,185,946,339,1582,2697,2960,2866,1585,949,1857,2486,818,2416,554,819,309,820,612,951,373,952,1679,1503,1228,1950,1412,377,1045,1046,77,1413,340,677,94,3277,556,1311,678,452,1048,2251,2917,378,1130,1131,614,1589,10,95,679,3288,78,222,1051,1233,3049,3080,1774,1133,119,1234,756,252,3245,1417,2495,151,456,1866,58,411,458,883,2056,1596,961,1964,2327,1418,2420,1867,884,1241,1693,3081,1324,2059,1695,1141,1326,886,761,3109,888,347,20,1057,1967,461,2162,1871,1602,3196,2707,889,1059,2647,891,1329,98,1696,1697,685,894,765,895,1700,510,3337,2771,1248,2433,161,280,573,39,2068,2772,1336,282,1705,1706,1975,258,2344,1530,1790,769,512,2714,2651,179,1977,2588,771,1707,260,1978,353,162,3015,899,2969,1341,900,1608,226,514,2777,164,630,1342,2270,1981,26,901,1795,3346,690,902,3137,1885,2658,386,2930,166,320,1439,2520,2074,473,2721,904,420,1259,474,1260,421,840,1165,357,1542,777,2522,1443,580,1615,83,2180,1616,1350,2181,154,1801,3239,701,122,2525,1080,3178,905,228,523,2185,2662,2978,213,906,524,2281,322,44,1719,45,2449,3240 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3367 Organelle subcompartment 66 348 3.9766688001697914 6.988739508972941e-05 O00560,Q15392,Q06136,Q99720,Q15437,P61353,Q9BUN8,Q9UBM7,Q99996,P53367,P84095,Q00765,Q96N66,O15260,Q99943,Q9H4L5,P48449,Q9HD20,Q8TC12,Q9NZ01,O95674,Q9P260,P26885,Q14739,P53621,Q96G23,Q96RL7,O75352,Q6NUM9,Q9BUR5,Q9H490,Q9BVC6,Q8WXH0,Q9H3N1,Q9BU23,Q8N2K0,Q15006,Q02809,Q9NX47,P60059,O95070,Q9BZF1,P07099,Q96S52,Q6NTF9,Q9HCU5,Q658Y4,Q14165,Q9NXW2,O43795,Q8N9F7,Q9Y5X1,O94874,Q2TAA5,Q9Y394,P50402,O60568,Q9BRR6,Q08379,Q92604,Q9H1C4,Q9Y4P3,O60725,P09496,P01889,Q6IAN0 Localization GO Cellular component msigdb_gocc 230,2,3,4,244,365,139,8,138,241,366,367,413,15,279,417,18,418,274,422,266,24,399,28,270,30,160,156,312,39,180,43,314,317,46,455,308,303,474,53,292,192,62,349,342,82,208,206,356,325,97,229,328,93,228,89,87,383,104,255,120,391,231,359,236,129 1271,704,1175,642,2729,846,2360,1084,230,1085,3091,2451,849,1456,1000,1087,2361,526,3215,15,527,1626,1459,3274,2094,1366,2098,325,914,647,87,231,915,2456,2985,2786,156,855,1368,2202,2203,2205,328,3252,1183,1184,1466,292,3061,1093,590,1727,531,591,266,1373,2791,1094,236,2606,1096,1554,649,3323,2380,62,1819,1730,359,1731,2539,3163,2290,3242,2465,2746,652,1193,2611,1288,484,860,2796,1381,399,3320,1824,791,1199,2543,792,3218,2849,2388,1200,1923,927,658,2619,3032,2019,2117,488,1018,2022,796,2392,18,2853,2550,1022,1207,2303,89,2474,1835,1564,1649,2689,2690,241,2124,270,1654,1485,1568,867,1213,935,53,802,3230,1215,1569,603,868,936,365,937,1749,2954,1396,807,3180,1217,2751,544,1663,366,735,367,1398,303,810,2998,3,1492,3232,104,872,1401,2405,547,1222,2560,1493,2033,1119,1667,873,1760,1848,3343,206,874,2040,28,2041,2959,2137,1406,308,1126,2243,1308,3298,3044,2,1040,244,2412,1675,1766,3151,553,1586,93,2867,1042,3361,2761,1043,1768,2145,1047,208,821,129,342,312,1506,2146,1229,1685,1508,749,559,1052,2640,2641,1961,3107,1516,755,453,680,455,2763,2260,882,1517,97,681,3195,1597,1692,1519,2156,2963,1240,274,2766,1867,1779,1600,1323,2819,757,314,2061,682,255,1869,1423,565,2161,1601,621,965,30,569,1873,1524,2263,892,2428,413,1699,160,349,1701,3011,3136,3012,4,972,279,1431,138,2926,383,2713,2873,2340,2169,46,139,39,43,2506,977,1529,192,1433,979,1792,467,120,1339,317,180,1708,417,1607,1794,82,418,1435,3237,984,1883,1256,1711,474,519,356,422,1541,776,1167,24,1797,2592,2828,8,1170,1616,1889,1716,3120,781,2353,3142,2596,1353,1267,1354,993,228,583,2358,1718,391,1896,229,1897,1357,1454 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3367 Envelope 160 455 3.563603680891976 0.0003657981152509 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Localization GO Cellular component msigdb_gocc 488,489,4,494,7,8,497,10,564,20,26,28,29,573,577,580,581,39,555,43,44,45,529,51,52,534,535,58,539,540,549,547,545,541,621,625,83,78,77,75,101,100,98,632,94,637,89,614,613,612,586,587,592,106,594,119,122,591,605,606,130,682,133,689,690,693,145,695,166,701,164,160,642,159,644,179,172,647,167,662,661,192,659,187,756,213,749,200,203,201,227,778,777,776,222,771,767,706,720,719,260,258,232,233,237,230,240,275,283,282,278,266,313,310,312,314,320,322,293,302,291,347,352,357,340,356,323,329,333,377,381,361,411,417,420,397,459,458,456,454,465,474,452,476,477,425,427,429,430,436,446,445,510,512,514,519,523,504,482,486 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3367 Mitochondrial envelope 127 288 3.3321706411824543 0.0008617140157189 P42345,O43772,Q70HW3,Q96AY3,Q9NPL8,P11310,Q9BT17,Q9NVS2,Q9UBX3,Q9UDW1,Q9BUR5,Q9Y5L4,Q9Y6C9,O75880,O95831,Q9BSK2,P05141,P09543,Q8N983,P40939,P43304,Q10713,Q02978,Q9BRJ2,Q9UDX5,Q7Z2W9,Q5VT66,O96008,Q9NZJ7,Q96I36,Q9NWX6,Q6DKK2,Q9Y2R5,Q6UXV4,Q4VC31,O43819,P08574,P20674,Q567V2,O95573,Q9Y2Q9,Q86Y39,Q00325,O75306,Q9NP92,Q9NR28,P56134,Q9UH62,Q9NVH0,Q9Y277,Q9HC21,Q96RL7,O00264,P82664,O15228,Q9H2D1,P51970,O60488,O00483,P50416,Q8IXI1,Q9Y3D3,P00403,P31040,P09001,Q9UG56,Q9P0J0,Q7Z434,Q9H2W6,P34897,P30405,Q9H3K2,Q9BYC9,P09669,O75251,P12532,P47985,Q9BXK5,Q3ZCQ8,O95674,Q16891,Q16134,Q6PI78,Q9NYK5,Q9NVH1,Q9Y512,O75439,P82912,O95182,O75616,O75600,Q96A26,Q9P015,Q5XKP0,Q96EY7,Q96GC5,Q92667,Q8NBU5,Q8N5K1,O95563,Q9BQ95,P53007,Q9H845,Q9H9J2,Q5T653,P21912,Q8NAN2,Q9NX14,P12236,Q8NBN7,Q8N442,Q9BU61,Q9NX47,Q6P1L8,Q9Y276,Q9Y291,O75746,O95299,P10606,P13073,P53701,Q96TC7,Q9BZE1,Q9HAV7,Q9Y399,Q8IXI2,P30536 Localization GO Cellular component msigdb_gocc 488,7,10,20,26,29,573,577,580,581,39,44,45,529,51,52,534,535,58,539,540,547,545,625,83,78,77,75,100,98,632,94,637,614,612,587,592,594,106,591,122,119,606,133,689,690,145,695,166,701,164,160,642,159,644,179,172,647,167,661,756,213,200,203,201,227,777,222,771,720,719,260,258,716,232,237,240,282,819,266,818,817,313,840,320,322,786,302,293,787,291,347,357,340,889,891,886,883,882,329,896,333,899,900,377,361,411,420,397,458,456,465,474,452,476,477,425,427,429,430,436,510,512,514,523,504,486 2092,642,2729,167,3251,2884,1900,1001,644,2192,2600,912,1277,7,587,1280,647,2984,2100,232,133,1181,916,786,2000,291,787,425,529,1632,1004,1553,918,2370,293,1633,427,329,591,266,51,3276,75,1094,200,2209,534,2105,2742,592,201,535,2539,716,429,1470,29,1638,397,237,430,3324,1472,859,2467,1193,1286,1194,594,2110,361,2682,2111,2218,2293,1382,2222,2113,2544,719,486,203,1477,1200,720,2116,1481,1830,1387,1925,539,488,540,1203,240,3034,1023,1024,1648,661,865,172,1107,1931,2856,333,436,1297,866,1027,145,1838,3040,1300,159,1940,1661,302,1662,939,606,2904,1490,545,547,1941,1119,1758,2241,2136,2908,2911,874,946,1853,2697,817,2960,2865,1585,818,819,612,951,106,377,1045,77,340,94,3277,1311,452,313,1130,614,3326,10,78,222,1051,1774,119,1234,756,504,3245,2922,2495,1056,456,882,1866,58,411,458,883,2056,1964,2327,2644,1867,1241,1324,1695,1141,1326,886,347,1522,20,1967,2925,2162,1602,889,891,1329,98,1697,160,1700,510,2710,1154,3337,2771,2433,896,625,52,573,465,1881,39,1157,1336,282,1705,258,2344,1530,1790,512,1066,179,771,260,1708,899,2969,2824,1341,900,1608,514,164,2270,689,26,1882,3346,690,1710,1344,3137,986,166,320,2520,577,2074,632,420,474,1260,840,100,357,1542,777,580,581,83,227,695,1350,1172,3239,476,701,477,122,2525,637,1080,993,3328,523,2185,2662,213,906,2281,322,44,45,2449 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3367 Ncrna metabolic process 123 309 3.279759403929221 0.0010389564775825 P42345,P55769,Q96GQ7,O15213,Q9NNW5,Q9NV88,Q9NY93,Q96DE0,Q13601,Q9ULX3,P62841,Q99848,Q9NWX6,Q9UI30,Q7L0Y3,Q9ULW3,Q9Y2R4,Q9Y2Z2,O95478,Q8WYQ5,O75818,Q96GW9,Q6DKI1,Q9UKN8,Q9NVH2,Q9NV06,Q13895,Q13206,P78527,P18077,P50914,O75691,P56182,Q9Y2X3,Q9NU22,Q15031,Q92945,Q8IZH2,Q8NHU6,Q9Y5Q8,Q76FK4,Q9BV38,Q9Y3B2,Q9HA77,Q9H7B2,Q9NQ55,Q9H0D6,Q6P1N0,Q9BYG3,Q9BVI4,Q8IY81,Q8N8A6,Q8TDN6,Q9H6R4,Q9H9Y6,O75367,O15091,P46100,P62875,Q9BZE4,Q9BRJ7,P49590,P22626,O76021,P62753,Q92841,Q5JTH9,Q969X6,Q9Y2W6,Q9GZL7,O43818,P82912,O60287,P50613,P62424,Q13428,P62857,P78345,Q9H583,Q96G21,O43159,Q6RFH5,Q96SY0,Q9BVJ6,Q9H0A0,Q9H9J2,Q12789,Q9NV31,Q9Y2Z4,Q6PI48,Q9Y5Q9,Q5SY16,O00541,O43290,P42285,P61353,P46777,Q7Z4G4,Q9NR30,Q99714,Q99575,Q96GM8,O75648,Q8IYB7,Q8IWA0,Q14692,Q9Y5J1,Q8NI36,Q8IY37,Q9NQT5,Q9NVP1,Q14690,Q15061,P55265,O15381,Q14978,P62847,Q14137,Q8WUA4,Q9NQZ2,Q9NX58,Q86U38,P42766 Processes and pathways GO Biological process msigdb_gobp 488,19,570,31,574,576,578,37,550,71,543,624,632,633,95,635,636,638,88,108,124,684,677,154,691,165,672,670,173,653,171,168,664,198,195,185,760,188,209,215,746,766,782,226,225,772,770,221,768,767,251,253,254,261,262,711,707,724,734,283,281,727,268,265,271,830,310,315,844,836,785,302,290,298,806,812,807,809,353,890,324,881,895,897,898,900,337,903,905,378,908,375,847,852,862,365,863,408,419,971,970,967,393,960,957,403,996,460,454,470,472,449,451,437,424,450,439,448,507,516,518,503,490 2830,3335,1993,847,2730,1362,1809,707,3186,31,424,2531,324,852,1724,2194,1461,785,290,1003,711,2369,393,168,2200,124,2001,265,1907,1005,2103,1186,1372,88,1816,3063,1913,2008,2013,1559,653,1473,2846,1011,268,2613,2294,1736,1831,3033,1388,2850,1644,862,488,490,1019,724,863,2023,2854,2394,727,2855,298,171,933,1932,3038,2395,437,19,664,2397,2306,2126,1028,1935,365,1937,1395,2902,1655,1030,806,271,543,439,1488,807,734,1573,2029,2237,809,1939,173,302,1113,3191,1491,2756,1402,337,1118,2031,670,812,550,1037,2036,672,448,1125,449,403,450,1407,185,2632,1580,451,1408,1948,2698,2416,1227,952,310,1503,3358,2047,1228,375,1950,2487,953,1505,2145,1414,1310,677,2811,221,378,881,1685,1507,746,1771,95,1772,408,503,1686,1863,3316,957,454,251,960,188,1417,2573,1056,1595,253,1318,209,460,1867,1319,254,1320,507,1322,2158,108,2159,830,760,1144,1870,1145,315,37,1148,2647,890,1969,967,570,684,3009,2500,2166,2333,895,970,971,624,1332,3157,281,1334,1249,1878,3158,766,2927,767,897,3213,1064,2172,1705,1158,1530,768,283,836,1338,1793,898,770,2585,2346,1707,2267,353,261,225,2175,2824,900,2347,2717,262,226,1255,574,1981,2176,2657,2718,772,1537,470,516,419,2518,1885,195,165,903,576,691,472,2932,632,1345,518,1887,1346,2075,578,3118,1347,1168,1613,1444,2180,633,1446,2724,154,635,71,1545,990,2355,1803,2782,3203,3058,3344,1892,1620,636,2936,844,198,638,905,2184,1083,2526,782,2978,2938,1718,1622,2663,1623,996,215,908,1719,3240 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3367 Ribonucleoprotein complex 169 444 3.177142490700015 0.0014873394063057 P42704,P62910,P62995,P61513,Q96E39,P55769,Q8IXT5,O15213,Q9NVS2,P62316,Q13601,P15880,Q8N983,Q9ULX3,P62841,P61978,P25398,Q9BRJ2,Q9Y3B4,Q99848,Q99729,Q9BWJ5,Q7Z2W9,P19474,Q8IUH3,Q7L0Y3,Q9Y2R5,P51991,O95478,Q9Y333,P31942,O43660,O75643,Q14103,Q567V2,P27635,Q9Y2Q9,P67809,Q00839,P61247,P46779,O75818,Q96QE5,Q96EP5,Q01081,Q6DKI1,Q14011,Q9NP92,P62888,Q9Y221,Q9NV06,Q13895,P63173,P61313,P82664,O75533,Q5VTL8,P78527,P18077,P50914,O75691,P56182,P32969,Q9Y3U8,Q9Y2X3,P62304,Q9NU22,P52948,P55795,O60508,Q9Y3D3,Q86US8,Q02880,P09001,Q9Y3T9,Q9NQ55,Q9H2W6,Q9BVI4,Q8IY81,Q9BYC9,Q9H6R4,P09234,Q96DF8,Q6P2Q9,O60231,O15091,P46782,P63244,Q13595,Q92917,P22626,O76021,P36578,P62753,P84098,Q92841,Q13523,Q14562,Q92616,Q9NYK5,Q969X6,Q9GZL7,O43818,P82912,P11388,P38159,P45973,P62424,P17844,P62917,P62857,P78345,Q9H583,Q9P015,Q96GC5,Q96G21,O60306,Q6RFH5,Q9BVJ6,Q9H0A0,Q07020,Q08211,Q12789,Q9H9J2,Q9NQ29,Q9NV31,Q5T653,Q96DI7,P09651,O00541,O43290,P42285,P61353,P46777,P62829,P51398,Q99714,Q99575,Q8IYB7,P14866,Q9BUQ8,Q02543,Q9Y312,Q14692,Q9Y5J1,Q8NI36,Q9H7N4,Q6P1L8,Q9Y291,Q14690,P55265,O15381,P18621,P39023,Q14978,P46778,P62847,Q12972,Q14137,Q06787,Q9HCS7,Q9BZE1,Q9NQZ2,Q9Y399,Q86U38,P42766,O43390,O75934,P31943 Localization GO Cellular component msigdb_gocc 489,493,494,492,567,19,560,31,577,41,550,537,58,71,543,542,74,625,85,624,623,79,78,76,96,95,637,90,88,112,598,586,589,105,106,597,122,605,114,604,601,124,685,683,136,677,148,689,146,700,165,672,158,157,159,648,175,173,653,171,168,664,657,199,198,665,195,662,663,183,213,750,205,201,783,772,771,767,251,258,261,715,256,246,709,707,725,242,739,276,268,265,269,271,272,830,306,307,829,840,315,836,785,302,790,794,795,806,295,808,807,809,353,357,891,890,326,881,897,898,335,336,337,900,901,903,377,380,857,847,852,862,365,863,871,865,971,970,960,398,976,401,992,403,996,460,469,452,477,449,437,424,431,433,450,434,439,447,448,443,515,512,516,523,503,490,480,481,487 2189,1993,847,2730,1362,1548,707,31,910,2362,424,1363,911,852,480,2095,2601,586,1460,2734,785,709,326,1002,183,1003,2368,648,589,168,2200,124,2201,1465,481,2002,265,1369,1370,1907,1005,1092,1187,88,2004,2006,1911,2285,2378,3063,1375,2941,1913,2607,1377,1008,2743,2008,2673,201,2381,715,857,2289,2463,1189,2943,790,2609,2384,1557,398,537,1916,295,2467,653,1473,431,2846,76,2890,1011,268,2218,74,2893,1102,2385,2223,597,1824,926,598,487,657,2228,1015,269,1016,2298,794,1104,1831,3033,433,1105,929,862,489,490,795,930,863,434,601,2299,725,2851,1294,1929,1021,1023,1207,171,1745,2123,865,90,1651,1209,1746,1931,662,3098,437,19,663,2396,664,2306,1028,2028,1839,2128,1748,2624,604,1935,157,365,492,3071,1029,542,1937,1395,1571,2902,1655,1299,2479,1396,1216,1112,665,1030,3332,41,1572,806,1397,1656,271,871,543,439,1488,807,146,1031,1573,493,2029,808,494,158,242,605,2237,809,1939,173,3040,159,1940,1661,302,1662,939,940,1218,272,1843,114,136,401,1114,205,1844,443,335,2484,336,1577,1402,337,2031,2032,1578,1303,447,1665,2958,1494,2562,2241,1942,306,2565,739,550,1403,672,148,105,448,1497,2911,307,1125,449,403,450,1579,1580,1762,1408,1674,2044,1409,1764,1500,1583,2960,948,1948,2318,1227,1677,106,377,175,1414,1953,677,1681,2811,452,246,1312,2572,881,1771,95,2324,2052,78,2253,2812,1509,1051,503,2053,750,1958,1593,96,3316,2152,560,251,2153,960,1595,1866,58,1318,2497,460,3154,2644,1867,1140,2924,2060,2159,1141,3247,2768,829,1422,830,2704,2062,276,1144,315,1522,1146,256,380,1602,567,683,890,3308,891,3009,1971,1527,685,1789,970,971,623,624,625,1249,2434,976,1335,767,897,3213,79,2172,1158,1975,258,2344,1530,512,1252,2509,836,2714,898,2652,1434,771,1533,3115,353,261,469,2716,900,2717,1535,1255,2971,515,2270,1343,689,2657,901,772,516,1344,3223,195,2974,165,903,1258,577,1163,1440,2932,1345,2075,3118,840,2722,357,1073,2076,2078,1715,2780,2723,1076,2724,2277,71,1173,1449,2444,1351,990,1619,2355,1546,700,2977,2183,2661,477,2087,122,637,1080,2936,198,992,112,3019,523,2184,1083,85,2185,2978,2186,213,783,199,1622,1895,996,2599,1454 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3367 SLC25 family of mitochondrial transporters 13 19 3.1338571255589285 0.0017252483702092 P53007,P12236,Q02978,Q9UBX3,O43772,O75746,Q9H2D1,Q70HW3,Q9Y6C9,Q9BSK2,Q9NZJ7,P05141,Q9HC21 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 333,397,545,580,7,425,179,10,45,52,100,534,164 7,1549,425,534,1638,397,333,606,545,1311,10,52,179,2969,164,100,580,1350,45 5.635301863617322,0.038183571311803624,0.7791325831371873,0.6799962288254567,-0.010993546587328921,0.8287386969157501,0.9280258355715242,0.6304663824403278,0.6799962288254567,0.18588511287864595,5.275776405771673,2.026393700295174,1.276298099702733,-0.8425099767812463,1.326146363804916,1.625718868683733,0.6799962288254567,0.18588511287864595,2.3277934623192205 3367 Mitochondrial carrier domain superfamily [IPR023395] 13 19 3.1338571255589285 0.0017252483702092 P53007,P12236,Q02978,Q9UBX3,O43772,O75746,Q9H2D1,Q70HW3,Q9Y6C9,Q9BSK2,Q9NZJ7,P05141,Q9HC21 Sequence InterPro Superfamily interpro_homologous_superfamily 333,397,545,580,7,425,179,10,45,52,100,534,164 7,1549,425,534,1638,397,333,606,545,1311,10,52,179,2969,164,100,580,1350,45 5.635301863617322,0.038183571311803624,0.7791325831371873,0.6799962288254567,-0.010993546587328921,0.8287386969157501,0.9280258355715242,0.6304663824403278,0.6799962288254567,0.18588511287864595,5.275776405771673,2.026393700295174,1.276298099702733,-0.8425099767812463,1.326146363804916,1.625718868683733,0.6799962288254567,0.18588511287864595,2.3277934623192205 3367 Mitochondrial substrate/solute carrier [IPR018108] 13 19 3.1338571255589285 0.0017252483702092 P53007,P12236,Q02978,Q9UBX3,O43772,O75746,Q9H2D1,Q70HW3,Q9Y6C9,Q9BSK2,Q9NZJ7,P05141,Q9HC21 Sequence InterPro Repeat interpro_repeat 333,397,545,580,7,425,179,10,45,52,100,534,164 7,1549,425,534,1638,397,333,606,545,1311,10,52,179,2969,164,100,580,1350,45 5.635301863617322,0.038183571311803624,0.7791325831371873,0.6799962288254567,-0.010993546587328921,0.8287386969157501,0.9280258355715242,0.6304663824403278,0.6799962288254567,0.18588511287864595,5.275776405771673,2.026393700295174,1.276298099702733,-0.8425099767812463,1.326146363804916,1.625718868683733,0.6799962288254567,0.18588511287864595,2.3277934623192205 3367 Transporters 78 338 3.0020812529336447 0.0026814059529902 P21333,Q99720,O43772,Q70HW3,O43681,O15260,Q92621,Q93050,Q2M389,Q96GC9,P41440,Q9UBX3,Q9BUR5,Q8IXU6,Q9BVC6,Q5SRE5,Q9Y6C9,O94973,Q9BSK2,P60059,P05141,Q9NR77,Q02978,P49790,Q9HCU5,O96008,Q9UH99,Q9NZJ7,Q14118,Q658P3,Q9H1C4,Q15287,P81605,O43933,Q9BUN8,Q9HC21,Q96RL7,Q9H2D1,Q9ULH0,Q9BZF1,P54709,P00403,P31040,P28288,O00560,P63244,Q8WYP5,Q9H3N1,Q9Y512,Q15006,P56589,Q6NTF9,Q96CW1,Q9C0E2,Q9NXW2,P30825,O00159,O75955,O95563,P53007,Q96EE3,P09496,P21912,Q96N66,Q9HD20,Q6ZXV5,O60684,P11166,P12236,Q9H0U3,Q9Y276,O75746,P10606,P13073,Q12769,P62873,Q9UI12,O94901 Functions Protein Atlas Protein class protein_atlas_protein_class 484,4,7,10,12,15,564,22,25,569,33,580,39,42,43,555,45,530,52,53,534,60,545,541,82,75,101,100,91,107,120,116,126,123,139,164,160,179,196,192,184,200,203,219,230,242,275,317,322,308,300,342,348,352,356,330,323,327,329,333,381,359,361,413,418,407,392,396,397,467,476,425,429,430,445,440,520,482 1271,323,1992,1899,1807,2729,1808,230,1809,706,2530,1900,1456,2361,1548,3309,3215,1458,15,1088,1627,1459,1364,12,1366,2098,7,1549,123,1280,2099,2602,3275,2455,392,1630,2534,3310,2100,2786,712,2367,1999,917,425,2202,2203,327,2205,1369,482,1183,530,1466,1633,1093,2537,2789,2372,3062,329,1728,2375,75,200,1095,3282,3291,2377,1096,1816,1554,649,2007,3323,534,1635,2380,1636,3093,3026,3347,2462,2792,359,1731,429,396,858,3253,3242,1638,397,1191,430,2010,2677,1472,652,921,1560,1288,594,2217,1917,484,361,1381,1197,219,330,203,2686,658,659,3068,1016,2298,2620,1831,2019,33,1203,2021,2022,1646,796,1022,1207,2303,541,797,661,2474,2122,1025,1564,602,2689,2476,662,333,1210,1653,3098,184,731,2951,1485,1568,300,935,1214,53,802,2624,2953,869,937,1749,803,938,440,3180,1841,1938,2751,242,1842,3039,126,606,735,545,2239,1492,1399,3259,1577,2405,445,1222,607,2560,1667,873,1403,3343,91,1405,3101,2959,2137,308,3287,2043,946,116,2412,1584,3151,2413,1855,818,25,3361,2761,1043,555,3311,2321,107,821,3303,3153,342,1311,1229,2489,1050,407,10,2325,1234,42,1137,2153,1690,3245,2155,2260,1517,1776,2057,3195,1238,1598,1239,1519,1419,2963,1240,2766,2329,1600,1321,3333,1139,1695,275,2421,564,1423,1784,22,2161,1601,621,348,381,569,1873,1150,3334,413,2579,1699,1972,160,1701,1429,4,3013,1062,2433,2337,2873,52,1879,139,39,43,2343,1528,1529,192,352,2650,467,120,179,1533,317,2716,2969,1341,1255,164,82,418,2516,3346,60,1070,1710,1256,2073,356,100,1167,2077,778,580,1798,1170,101,1715,520,1349,2524,1350,2879,1717,2880,196,1352,2446,476,993,3328,2358,1804,2091,322,2727,2599,1269,45 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3367 Ragged red muscle fibers 9 16 2.981008892608185 0.0028730044994986 Q9H2D1,Q70HW3,Q9BQP7,O95831,P00403,P31040,O75648,Q9HA77,Q9Y276 Drugs and Diseases Human Phenotype Ontology msigdb_hp 179,10,280,51,200,203,393,226,476 2786,393,51,200,1638,203,729,1754,952,10,509,280,179,226,476,1990 -0.6963789999906698,0.8287386969157501,2.026393700295174,1.1766720264729662,-0.010993546587328921,1.1766720264729662,0.5314843607251645,-0.06014188297173856,0.38320863530356236,5.275776405771673,0.7295516952751605,1.027411607598693,1.276298099702733,1.1268945552711775,0.7791325831371873,-0.15835117828187525 3367 Abnormal circulating metabolite concentration 83 356 2.977448296898271 0.0029065866416431 P48735,Q15392,P60891,O43772,Q9UBM7,Q02241,Q70HW3,Q969N2,Q92621,Q9NPL8,Q14739,P11310,P41440,Q9NZB8,Q9UBS4,O75880,O95831,P40939,Q02978,Q9NZJ7,Q9HCC0,Q7L0Y3,Q9UJX6,Q14118,Q9Y2Z2,P50402,Q8WYQ5,O43819,Q658P3,O95470,P08574,P00367,P09622,P20674,P23378,Q9H1C4,Q86Y39,P35573,P36776,O43933,Q99996,O76075,O75306,Q00059,Q96RL7,Q8N5M1,O14979,P31040,P14174,P09001,P28288,Q9NZC9,Q7Z5J4,Q96DF8,O75251,P47985,Q9BQP7,P22626,P53621,Q4G0N4,Q8WXH0,P05166,P28070,P30038,P56589,Q5XKP0,Q15120,P42858,Q9P2R3,Q9Y4P3,P21912,Q9NX14,Q9Y487,Q6ZXV5,O75648,P11166,Q15833,Q9BU61,Q9Y276,Q12965,Q12769,Q96RR1,Q9NWH9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,2,6,7,8,496,10,565,564,26,28,29,33,579,48,529,51,539,545,100,630,95,634,91,638,89,108,587,107,590,592,103,593,594,595,120,119,599,600,123,138,134,133,147,160,178,181,203,202,201,219,263,247,256,232,240,280,268,270,309,314,294,296,297,300,340,339,332,388,391,361,420,423,407,393,396,404,465,476,446,445,509,517 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3367 Muscle fiber atrophy 7 20 2.754756643030451 0.0058735804791623 Q96RL7,P50402,Q99720,Q8WXH0,Q02809,P22626,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 160,89,4,314,303,268,331 2538,1815,1284,2383,268,2293,331,89,333,542,303,1754,2567,1232,1867,314,160,4,975,1981 -0.5011441622286765,-0.10926118080988163,0.18588511287864595,-0.4033529535656676,1.027411607598693,-0.35441285400454997,0.9280258355715242,1.625718868683733,0.9280258355715242,0.6799962288254567,0.9777064845725953,-0.06014188297173856,-0.5011441622286765,0.23517487778404642,-0.10926118080988163,0.9777064845725953,1.326146363804916,7.443286148292555,0.38320863530356236,-0.15835117828187525 3367 Nuclear outer membrane 7 10 2.7299280909811388 0.0063348141771655 P50402,Q99720,Q6NUM9,Q8WXH0,Q9UBM7,Q9BVC6,Q9NXE4 Localization GO Cellular component msigdb_gocc 89,4,312,314,8,43,519 2210,489,89,1936,312,314,4,43,519,8 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3367 Fatty acid betaoxidation 11 19 2.559582676311164 0.0104797925127022 Q92947,O43772,P43304,P09622,O60488,P24752,O95573,P50416,P40939,P30084,P11310 Processes and pathways WikiPathways msigdb_wp 761,7,540,593,647,656,591,661,539,485,29 7,647,591,593,29,2293,656,485,1200,927,539,723,540,1024,661,1027,1298,1857,761 5.635301863617322,0.5809623580063942,0.6304663824403278,0.6304663824403278,2.83174577665665,-0.35441285400454997,0.5809623580063942,0.7295516952751605,0.23517487778404642,0.38320863530356236,0.6799962288254567,0.5314843607251645,0.6799962288254567,0.3338368679188049,0.5809623580063942,0.3338368679188049,0.18588511287864595,-0.10926118080988163,0.5314843607251645 3367 Intellectual disability progressive 9 18 2.551092929254873 0.0107385688423553 Q96HA7,O43933,Q6P1N0,Q15067,O95721,P19447,P53701,O95831,Q9NX14 Drugs and Diseases Human Phenotype Ontology msigdb_hp 189,123,221,674,428,654,436,51,420 123,428,51,1559,654,1106,724,1393,436,1845,674,221,964,189,1339,1608,420,1443 1.4758300898493955,0.7791325831371873,2.026393700295174,0.038183571311803624,0.5809623580063942,0.28449220643173684,0.5314843607251645,0.13662314668544415,0.7791325831371873,-0.10926118080988163,0.5809623580063942,1.1268945552711775,0.38320863530356236,1.226473264687721,0.18588511287864595,0.038183571311803624,0.8287386969157501,0.13662314668544415 3367 Deviation of the thumb 7 16 2.5431760449240515 0.0109849867598987 P21333,Q9UBM7,P34897,Q96ST3,O60216,Q9Y3E5,P36776 Drugs and Diseases Human Phenotype Ontology msigdb_hp 484,8,720,415,528,524,600 528,712,484,720,600,1104,1831,1215,1840,1945,1579,1415,415,8,1891,524 0.6799962288254567,0.5314843607251645,0.7295516952751605,0.5314843607251645,0.6304663824403278,0.28449220643173684,-0.10926118080988163,0.23517487778404642,-0.10926118080988163,-0.15835117828187525,0.038183571311803624,0.13662314668544415,0.8287386969157501,5.481130433252247,-0.10926118080988163,0.7295516952751605 3367 Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 11 13 2.5245715704464584 0.0115839414642302 Q9BYG3,Q8IY81,Q9BZE4,Q6DKI1,Q9GZL7,Q5SY16,P42766,Q9H7B2,Q14137,Q9NVP1,O60287 Processes and pathways GO Biological process msigdb_gobp 768,251,283,677,836,375,490,225,448,472,290 847,290,1473,490,448,375,677,251,768,283,836,225,472 0.43260728550341354,0.9777064845725953,0.0873892183509377,0.7295516952751605,0.7791325831371873,0.8783698441961026,0.5809623580063942,1.0771410238516028,0.5314843607251645,1.027411607598693,0.4820325991962496,1.1268945552711775,0.7791325831371873 3367 Abnormal conjugate eye movement 94 325 2.429337265329047 0.0151264538406157 P42345,P42704,Q15392,P21333,Q99720,P60891,Q9UBM7,Q969N2,Q9NPL8,Q14739,P10412,O60216,O96028,P40939,Q10713,P19022,Q9NZJ7,Q9NWX6,Q9UJX6,Q2TAA5,Q7Z3K3,O43819,O95470,P27635,Q86Y39,P36776,Q00839,Q12948,O43933,Q96HP0,Q9H2P0,Q15067,Q6NVY1,O75306,Q9UIG0,Q9H7D7,Q7L2E3,Q96RL7,P61313,O75352,Q9H490,Q71SY5,P10515,P18077,P19447,O60488,O00483,Q13148,Q9ULH0,Q15031,P55795,Q93008,Q8WWQ0,P31040,Q9Y3B2,Q9P0J0,Q2M1P5,P35222,P34897,Q9H9Y6,Q7Z5J4,O75251,P40926,P46100,P55011,Q02809,P30038,P56589,P35637,P53007,Q07020,P42858,Q9Y4P3,P61353,Q969G3,Q96ST3,Q9NX14,Q9Y487,O75648,P11166,Q96C36,Q8IY37,Q9BU61,Q9NQT5,Q8IY17,O95299,P62847,Q06787,P62873,Q8NI27,Q96RR1,Q9Y3E5,P42766,P30084 Drugs and Diseases Human Phenotype Ontology msigdb_hp 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3367 Polyneuropathy 7 18 2.424794628280467 0.0153170489377267 P60891,Q6PI48,Q8N2K0,O95831,Q15120,Q9NZJ7,Q9HC21 Drugs and Diseases Human Phenotype Ontology msigdb_hp 6,378,455,51,339,100,164 1280,428,51,1374,3093,2610,1477,2301,6,1301,1126,339,378,455,1065,164,100,3140 0.18588511287864595,0.7791325831371873,2.026393700295174,0.13662314668544415,-1.0369714996514596,-0.5499958789251567,0.0873892183509377,-0.35441285400454997,5.892546123554725,0.18588511287864595,0.28449220643173684,0.9280258355715242,0.8783698441961026,0.7791325831371873,0.3338368679188049,1.326146363804916,1.625718868683733,-1.0855207516489227 3367 Endonucleolytic cleavage involved in rrna processing 6 13 2.4084074892445364 0.0160222863937709 O75818,Q14692,O75691,Q5SY16,Q86U38,Q14137 Processes and pathways GO Biological process msigdb_gobp 124,403,168,375,503,448 168,124,2237,1402,448,403,1580,1948,375,503,1318,635,1620 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3367 Branched chain amino acid metabolic process 11 17 2.3168412487898298 0.0205123811354588 Q6NVY1,P09622,P24752,Q99714,Q96RQ3,O15382,Q9HCC0,P35914,A1L0T0,P30084,P35610 Processes and pathways GO Biological process msigdb_gobp 678,593,656,971,765,851,630,928,704,485,927 704,851,593,920,1475,656,1383,485,1478,927,928,1927,1219,678,765,971,630 0.5314843607251645,0.43260728550341354,0.6304663824403278,0.38320863530356236,0.0873892183509377,0.5809623580063942,0.13662314668544415,0.7295516952751605,0.0873892183509377,0.38320863530356236,0.38320863530356236,-0.15835117828187525,0.23517487778404642,0.5809623580063942,0.5314843607251645,0.38320863530356236,0.6304663824403278 3367 Decreased plasma carnitine 6 12 2.2881836667645867 0.0221268274745687 Q4G0N4,O43772,O75880,O75648,P40939,P11310 Drugs and Diseases Human Phenotype Ontology msigdb_hp 309,7,529,393,539,29 7,393,529,593,29,2293,928,539,1024,1857,309,899 5.635301863617322,0.8287386969157501,0.6799962288254567,0.6304663824403278,2.83174577665665,-0.35441285400454997,0.38320863530356236,0.6799962288254567,0.3338368679188049,-0.10926118080988163,0.9777064845725953,0.43260728550341354 3367 Chromosome partition 9 20 2.246278670314926 0.0246861639096693 Q93008,Q96EE3,Q96BM9,Q8NG31,O60216,Q8N3U4,Q96T76,P05141,Q14980 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 762,381,622,619,528,617,191,534,610 1809,2097,1365,528,534,1559,1826,610,1682,617,1238,1598,619,762,622,381,1427,191,1430,837 -0.10926118080988163,-0.256442200081617,0.13662314668544415,0.6799962288254567,0.6799962288254567,0.038183571311803624,-0.10926118080988163,0.6304663824403278,-0.010993546587328921,0.6304663824403278,0.23517487778404642,0.038183571311803624,0.6304663824403278,0.5314843607251645,0.6304663824403278,0.8783698441961026,0.13662314668544415,1.226473264687721,0.13662314668544415,0.4820325991962496 3367 Mitochondrial long chain fatty acid betaoxidation 6 12 2.240498100704336 0.025058603944073 O43772,O60488,O95573,P50416,P40939,P11310 Processes and pathways WikiPathways msigdb_wp 7,647,591,661,539,29 7,647,591,29,1476,2293,1200,539,723,1024,661,1857 5.635301863617322,0.5809623580063942,0.6304663824403278,2.83174577665665,0.0873892183509377,-0.35441285400454997,0.23517487778404642,0.6799962288254567,0.5314843607251645,0.3338368679188049,0.5809623580063942,-0.10926118080988163 3367 primary active transporter 6 16 2.2309042762395896 0.0256874704265479 P54709,Q6NTF9,Q9BUN8,O60888,O96008,P60059 Functions Panther Protein class panther_protein_class 184,342,139,47,75,53 47,2367,918,75,2007,1191,652,1560,184,53,1584,342,139,1341,514,3137 2.1267769822756275,-0.4033529535656676,0.38320863530356236,1.6757266391963095,-0.20741160864294675,0.23517487778404642,0.5809623580063942,0.038183571311803624,1.226473264687721,1.9762337611499756,0.038183571311803624,0.9280258355715242,1.4259125205867929,0.18588511287864595,0.7295516952751605,-1.0855207516489227 3367 Cytochrome complex assembly 7 11 2.213059851189968 0.0268935196040795 P47985,P53701,O75880,Q9BSK2,Q96I36,Q6DKK2,Q9Y276 Processes and pathways GO Biological process msigdb_gobp 240,436,529,52,98,94,476 587,529,240,436,946,94,98,52,986,476,2525 0.6304663824403278,0.6799962288254567,1.0771410238516028,0.7791325831371873,0.38320863530356236,1.625718868683733,1.625718868683733,2.026393700295174,0.38320863530356236,0.7791325831371873,-0.45226328736089716 3367 Secondary active transmembrane transporter activity 8 17 2.2123675464843444 0.0269412793884109 P53007,P12236,P41440,Q02978,Q9UBX3,P05141,Q00325,P51798 Functions GO Molecular function msigdb_gomf 333,397,33,545,580,534,606,602 1633,534,2462,1638,397,33,602,333,1653,731,606,545,2043,1584,1964,2969,580 -0.010993546587328921,0.6799962288254567,-0.45226328736089716,-0.010993546587328921,0.8287386969157501,2.579522168150364,0.6304663824403278,0.9280258355715242,-0.010993546587328921,0.5314843607251645,0.6304663824403278,0.6799962288254567,-0.20741160864294675,0.038183571311803624,-0.15835117828187525,-0.8425099767812463,0.6799962288254567 3367 Abnormality of the curvature of the vertebral column 48 324 2.2028482423510845 0.0276054466347064 P48735,P21912,Q99720,Q15437,P60891,Q13155,Q9UBM7,Q969G3,O75874,Q9BQP7,Q96ST3,P48449,Q96AY3,P22626,Q9Y487,Q6ZXV5,O75648,Q14739,P07237,Q9NUQ7,Q8WXH0,Q9H490,P10412,Q71SY5,Q96C36,Q02809,O95831,Q9NR77,Q96HA7,Q96S52,Q9UG56,Q2TAA5,P35637,Q14118,P53007,P50402,O60568,O75530,P42858,Q9NZC9,Q7Z5J4,Q32P28,Q9Y4P3,Q00839,P04350,O75531,P17480,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 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3367 Activation of anterior hox genes in hindbrain development during early embryogenesis 7 17 2.1905844515518957 0.0284818773274146 P62805,O75530,P30876,P62875,Q9UBL3,Q15291,P16104 Processes and pathways Reactome Pathways msigdb_reactome 334,217,432,734,694,611,63 2193,217,63,1287,2216,1640,432,1394,733,1750,334,734,2139,611,1520,694,1987 -0.3054426755723461,1.1268945552711775,1.8258823890778446,0.18588511287864595,-0.3054426755723461,-0.010993546587328921,0.7791325831371873,0.13662314668544415,0.5314843607251645,-0.06014188297173856,0.9280258355715242,0.5314843607251645,-0.256442200081617,0.6304663824403278,0.0873892183509377,0.5809623580063942,-0.15835117828187525 3367 Focal t2 hyperintense basal ganglia lesion 9 18 2.173536525713952 0.029739959846871 P42704,O95299,P53597,O75306,O00483,P31040,O75251,Q9P0J0,P30084 Drugs and Diseases Human Phenotype Ontology msigdb_hp 489,427,729,133,167,203,232,777,485 2092,167,232,133,2000,427,788,1194,2113,485,203,489,1648,729,1585,2495,2162,777 -0.256442200081617,1.276298099702733,1.0771410238516028,1.4259125205867929,-0.20741160864294675,0.7791325831371873,0.4820325991962496,0.23517487778404642,-0.256442200081617,0.7295516952751605,1.1766720264729662,0.7295516952751605,-0.010993546587328921,0.5314843607251645,0.038183571311803624,-0.45226328736089716,-0.256442200081617,0.5314843607251645 3367 Synthesis of pa 6 9 2.153268850406984 0.0312975553820982 Q86UL3,O15228,Q8NAN2,Q99943,Q9NPH0,P43304 Processes and pathways Reactome Pathways msigdb_reactome 559,644,411,279,23,540 644,540,559,1056,825,411,1597,279,23 0.5809623580063942,0.6799962288254567,0.6799962288254567,0.3338368679188049,0.4820325991962496,0.8287386969157501,0.038183571311803624,1.027411607598693,3.084450030727684 3367 Organic anion transmembrane transporter activity 11 25 2.1519060453927707 0.0314047550266884 P53007,P41440,P12236,Q9UBX3,O75746,Q9H2D1,P30825,P05141,O95563,Q9HC21,P11166 Functions GO Molecular function msigdb_gomf 333,33,397,580,425,179,330,534,329,164,396 2530,1549,425,329,534,2462,396,1638,397,330,33,333,1653,545,1584,1311,1229,1240,1062,179,2969,1341,164,580,1350 -0.5011441622286765,0.038183571311803624,0.7791325831371873,0.9280258355715242,0.6799962288254567,-0.45226328736089716,0.8287386969157501,-0.010993546587328921,0.8287386969157501,0.9280258355715242,2.579522168150364,0.9280258355715242,-0.010993546587328921,0.6799962288254567,0.038183571311803624,0.18588511287864595,0.23517487778404642,0.23517487778404642,0.3338368679188049,1.276298099702733,-0.8425099767812463,0.18588511287864595,1.326146363804916,0.6799962288254567,0.18588511287864595 3367 Excessive daytime somnolence 6 17 2.15187256747531 0.0314073923932247 Q96RR1,P42858,P60891,Q9UBM7,Q969G3,Q9H1C4 Drugs and Diseases Human Phenotype Ontology msigdb_hp 509,332,6,8,412,120 3189,656,538,721,927,928,3149,332,6,1118,412,509,2168,1429,120,8,997 -1.2794604438035604,0.5809623580063942,0.6799962288254567,0.5314843607251645,0.38320863530356236,0.38320863530356236,-1.1340440384713235,0.9280258355715242,5.892546123554725,0.28449220643173684,0.8287386969157501,0.7295516952751605,-0.256442200081617,0.13662314668544415,1.5257704412624165,5.481130433252247,0.38320863530356236 3367 Branched chain amino acid catabolic process 10 16 2.150648973213543 0.0315039167468131 Q6NVY1,P09622,P24752,Q99714,Q96RQ3,O15382,Q9HCC0,P35914,P30084,P35610 Processes and pathways GO Biological process msigdb_gobp 678,593,656,971,765,851,630,928,485,927 851,593,920,1475,656,1383,485,1478,927,928,1927,1219,678,765,971,630 0.43260728550341354,0.6304663824403278,0.38320863530356236,0.0873892183509377,0.5809623580063942,0.13662314668544415,0.7295516952751605,0.0873892183509377,0.38320863530356236,0.38320863530356236,-0.15835117828187525,0.23517487778404642,0.5809623580063942,0.5314843607251645,0.38320863530356236,0.6304663824403278 3367 Mutism 6 17 2.1369275237282883 0.0326038869518212 P42858,P60891,Q8IYA6,Q9NX14,P22626,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 332,6,345,420,268,331 846,857,268,331,332,1393,436,1485,6,669,813,3302,1945,1853,345,1980,420 0.43260728550341354,0.43260728550341354,1.027411607598693,0.9280258355715242,0.9280258355715242,0.13662314668544415,0.7791325831371873,0.0873892183509377,5.892546123554725,0.5809623580063942,0.4820325991962496,-1.810768611489318,-0.15835117828187525,-0.10926118080988163,0.9280258355715242,-0.15835117828187525,0.8287386969157501 3367 Toe walking 7 25 2.1328875270091747 0.0329339537837083 P50402,Q99720,Q8WXH0,O43681,O95831,Q9NZJ7,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 89,4,314,12,51,100,331 12,51,2538,1284,3093,1010,331,539,89,333,866,1485,1027,1301,1758,2567,2920,1237,3050,314,3109,4,975,100,1805 4.712311058916162,2.026393700295174,-0.5011441622286765,0.18588511287864595,-1.0369714996514596,0.3338368679188049,0.9280258355715242,0.6799962288254567,1.625718868683733,0.9280258355715242,0.43260728550341354,0.0873892183509377,0.3338368679188049,0.18588511287864595,-0.06014188297173856,-0.5011441622286765,-0.7938272123275193,0.23517487778404642,-0.9397941363276027,0.9777064845725953,-1.0369714996514596,7.443286148292555,0.38320863530356236,1.625718868683733,-0.06014188297173856 3367 Decreased activity of mitochondrial complex iv 9 16 2.118642201802309 0.034120716351111 P42704,Q96RP9,Q70HW3,P53597,P13073,P20674,Q9HA77,O00483,P43897 Drugs and Diseases Human Phenotype Ontology msigdb_hp 489,894,10,729,430,594,226,167,660 167,2194,430,594,489,660,1931,729,1300,952,10,894,2585,226,2525,906 1.276298099702733,-0.3054426755723461,0.7791325831371873,0.6304663824403278,0.7295516952751605,0.5809623580063942,-0.15835117828187525,0.5314843607251645,0.18588511287864595,0.38320863530356236,5.275776405771673,0.43260728550341354,-0.5011441622286765,1.1268945552711775,-0.45226328736089716,0.43260728550341354 3367 Regulation of gliogenesis 6 11 2.1109245629835462 0.0347787964345198 P42345,Q14118,Q92769,O94874,Q96G23,P30536 Processes and pathways GO Biological process msigdb_gobp 488,91,758,328,30,486 1455,328,486,721,488,1121,91,758,30,1449,2355 0.0873892183509377,0.9280258355715242,0.7295516952751605,0.5314843607251645,0.7295516952751605,0.28449220643173684,1.625718868683733,0.5314843607251645,2.83174577665665,0.13662314668544415,-0.35441285400454997 3367 Abnormal mitochondria in muscle tissue 7 20 2.0957834498706496 0.0361014051460555 O75306,Q9NX14,P00403,P31040,Q86Y39,Q9NPL8,O75251 Drugs and Diseases Human Phenotype Ontology msigdb_hp 133,420,200,203,119,26,232 2092,1277,232,133,2000,3276,200,1194,2113,203,1648,119,2495,2162,465,26,420,1542,2281,2449 -0.256442200081617,0.18588511287864595,1.0771410238516028,1.4259125205867929,-0.20741160864294675,-1.617898705564265,1.1766720264729662,0.23517487778404642,-0.256442200081617,1.1766720264729662,-0.010993546587328921,1.5257704412624165,-0.45226328736089716,-0.256442200081617,0.7791325831371873,2.9327705707558476,0.8287386969157501,0.0873892183509377,-0.3054426755723461,-0.4033529535656676 3367 Feeding difficulties 116 358 2.0827340975896496 0.0372754675906277 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3367 Congenital diaphragmatic hernia 13 24 2.076211021959685 0.0378744383274876 P21333,Q7Z3K3,P62857,Q9UBM7,Q9Y4A5,Q2M1P5,Q96ST3,O60216,Q8N3U4,Q9NX14,P53701,O96028,Q8IYB7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 484,615,807,8,584,743,415,528,617,420,436,532,960 1457,528,1466,1633,532,2009,484,2121,436,807,1223,1945,743,1415,956,615,960,617,415,2715,420,8,1891,584 0.0873892183509377,0.6799962288254567,0.0873892183509377,-0.010993546587328921,0.6799962288254567,-0.20741160864294675,0.7295516952751605,-0.256442200081617,0.7791325831371873,0.4820325991962496,0.23517487778404642,-0.15835117828187525,0.5314843607251645,0.13662314668544415,0.38320863530356236,0.6304663824403278,0.38320863530356236,0.6304663824403278,0.8287386969157501,-0.5988187323015277,0.8287386969157501,5.481130433252247,-0.10926118080988163,0.6799962288254567 3367 Abnormal circulating fatty acid concentration 8 19 2.071139164830335 0.0383457927569681 P56589,Q4G0N4,O43933,O43772,O75880,O75648,P40939,P11310 Drugs and Diseases Human Phenotype Ontology msigdb_hp 300,309,123,7,529,393,539,29 7,123,2367,916,393,529,593,29,2293,928,539,1024,1650,1027,300,1857,309,899,3299 5.635301863617322,1.4758300898493955,-0.4033529535656676,0.38320863530356236,0.8287386969157501,0.6799962288254567,0.6304663824403278,2.83174577665665,-0.35441285400454997,0.38320863530356236,0.6799962288254567,0.3338368679188049,-0.010993546587328921,0.3338368679188049,0.9777064845725953,-0.10926118080988163,0.9777064845725953,0.43260728550341354,-1.762585833650087 3367 Abnormal head movements 7 13 2.0647158958326117 0.0389498896482376 Q96RL7,Q99720,P11166,Q6NVY1,Q969N2,Q06787,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 160,4,396,678,565,443,331 650,396,2015,2681,331,3149,1301,443,1038,678,565,160,4 0.5809623580063942,0.8287386969157501,-0.20741160864294675,-0.5988187323015277,0.9280258355715242,-1.1340440384713235,0.18588511287864595,0.7791325831371873,0.3338368679188049,0.5809623580063942,0.6799962288254567,1.326146363804916,7.443286148292555 3367 Response to acid chemical 10 22 2.0647019765399115 0.0389512074605118 P42345,Q9UQB8,O43504,P26358,Q14103,O95831,O94874,Q9Y2Q5,Q6IAA8,P42574 Processes and pathways GO Biological process msigdb_gobp 488,35,72,538,105,51,328,61,406,363 1899,72,918,328,51,2009,859,538,793,488,363,2121,2301,1930,105,1853,406,3304,623,1613,35,61 -0.15835117828187525,1.7257565807765058,0.38320863530356236,0.9280258355715242,2.026393700295174,-0.20741160864294675,0.43260728550341354,0.6799962288254567,0.4820325991962496,0.7295516952751605,0.8783698441961026,-0.256442200081617,-0.35441285400454997,-0.15835117828187525,1.5757334188139989,-0.10926118080988163,0.8287386969157501,-1.810768611489318,0.6304663824403278,0.038183571311803624,2.579522168150364,1.9260951373543165 3367 Signaling by retinoic acid 6 9 2.0486067018733536 0.0405005887823448 P10515,P09622,Q8NBN7,Q8TC12,Q15120,P50416 Processes and pathways Reactome Pathways msigdb_reactome 650,593,458,274,339,661 788,593,650,1098,661,1581,339,458,274 0.4820325991962496,0.6304663824403278,0.5809623580063942,0.28449220643173684,0.5809623580063942,0.038183571311803624,0.9280258355715242,0.7791325831371873,1.027411607598693 3367 Ribonucleoprotein complex biogenesis 110 293 2.0340973156108944 0.041941784580999 Q5C9Z4,P55769,Q96GQ7,O15213,Q9NY93,Q96DE0,P62316,Q13601,Q9ULX3,P62841,Q99848,Q9UI30,Q9ULW3,Q9Y2R4,O95478,Q9Y333,O75643,Q567V2,P27635,Q9Y3C1,O75818,Q6DKI1,Q9Y221,Q9NV06,Q13895,Q9H9L3,Q7L2E3,P63173,Q13823,Q13206,O75533,P78527,P18077,P50914,P56182,O75691,Q9Y2X3,P62304,Q9NU22,Q76FK4,Q9BV38,Q9Y3T9,Q9Y3B2,Q9H7B2,Q9NQ55,Q9H0D6,Q9BYG3,Q9BVI4,Q96MU7,Q8IY81,Q8N8A6,Q8TDN6,Q9BYC9,P09234,Q9H6R4,Q6P2Q9,P46782,Q9BZE4,O76021,P62753,Q92841,Q5JTH9,Q969X6,Q9ULC4,Q9GZL7,O43818,P82912,O75616,O43809,O60287,P62424,P62857,P78345,Q9H583,Q9BQG0,P55010,Q9NWT1,Q96G21,O43159,Q6RFH5,Q9BVJ6,Q9H0A0,Q08211,Q9NV31,Q9NQ29,Q5SY16,O00541,O43290,P42285,P61353,Q9NR30,Q14692,Q8NI36,Q8IY37,Q9NQT5,Q9NVP1,Q14690,Q15061,P55265,O15381,P39023,Q14978,P62847,Q14137,Q9HCS7,Q9NQZ2,Q9NX58,Q9Y399,Q86U38,P42766 Processes and pathways GO Biological process msigdb_gobp 500,19,570,31,578,37,41,550,71,543,624,633,635,636,88,112,589,106,597,131,124,677,700,165,672,163,679,158,671,670,648,173,653,171,664,168,198,665,195,746,766,783,782,225,772,770,768,767,257,251,253,254,258,715,261,246,725,283,265,271,830,310,315,842,836,785,302,787,289,290,806,807,809,353,351,800,355,890,324,881,897,898,336,903,901,375,847,852,862,365,419,403,460,454,470,472,449,451,437,424,433,450,439,448,515,516,518,523,503,490 1993,847,2730,1362,1809,1455,1548,31,424,2193,324,852,2095,2667,1724,289,785,290,1003,1552,1726,648,2369,787,589,1091,168,2200,124,265,1370,1907,1092,1187,88,1911,2378,2941,2838,2792,2008,2673,715,2384,1916,1559,653,1473,2679,1011,2614,597,2229,1831,3033,433,1105,1926,862,490,1019,863,725,171,1746,3098,800,437,19,664,2306,1028,2953,1935,365,1937,1395,2902,1655,665,1030,3332,41,1572,806,1656,271,938,543,439,1488,807,1573,2029,158,2237,809,1939,1751,173,302,940,1113,1114,1491,2239,2484,336,1577,1402,2693,2032,670,1669,2135,2628,550,1037,2695,2406,671,1403,2036,672,448,1497,1125,449,403,450,2569,1407,1580,3129,451,1762,1408,1409,1764,1500,948,1856,1948,1677,106,500,310,3358,2047,375,2320,1414,677,2322,246,881,746,679,2253,1509,2255,503,2053,1863,3316,957,454,251,1417,1235,253,1318,460,1319,254,1320,1421,1322,1140,2159,830,2704,1144,1870,315,1057,1147,37,890,3308,570,3009,257,2166,1427,1429,2430,624,351,1249,976,766,767,897,3213,1158,1975,258,1530,768,283,1252,836,1338,1253,898,770,2346,2267,353,261,225,2175,163,2717,515,2176,2657,901,772,1537,470,516,419,195,2930,165,903,1258,472,1162,1713,2932,355,1345,518,2075,1261,578,3118,1165,1347,1263,2081,3119,633,1076,2724,842,635,71,1449,1545,990,2355,1803,700,2977,3203,2661,1892,1620,636,1080,2936,198,992,112,3019,523,2184,1083,2526,782,2978,131,2527,783,1622,1895,1623,996,3240 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3367 Abnormal brainstem mri signal intensity 6 19 2.0334732156742588 0.0420047369224554 O75306,O95831,Q86Y39,Q9NX14,Q9NPL8,O75251 Drugs and Diseases Human Phenotype Ontology msigdb_hp 133,51,119,420,26,232 2092,1277,232,133,2000,51,3276,1194,2113,797,1648,119,2495,2162,465,26,420,1542,2449 -0.256442200081617,0.18588511287864595,1.0771410238516028,1.4259125205867929,-0.20741160864294675,2.026393700295174,-1.617898705564265,0.23517487778404642,-0.256442200081617,0.4820325991962496,-0.010993546587328921,1.5257704412624165,-0.45226328736089716,-0.256442200081617,0.7791325831371873,2.9327705707558476,0.8287386969157501,0.0873892183509377,-0.4033529535656676 3367 Platyspondyly 11 38 2.030956441047783 0.0422594134880029 P48735,Q9NUQ7,Q96HA7,O60568,O75874,O95831,Q96AY3,Q9NZC9,Q32P28,Q9Y2Q9,Q14739 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,34,189,87,13,51,20,263,117,122,28 1084,3313,1995,87,712,13,51,1374,3283,484,1380,2223,1014,1,1563,1940,1398,303,2035,28,1307,117,1043,1311,1506,454,2819,20,189,1524,892,1606,2440,34,263,2934,2447,122 0.28449220643173684,-1.955180761540612,-0.20741160864294675,1.625718868683733,0.5314843607251645,4.661180688774601,2.026393700295174,0.13662314668544415,-1.6661510716682535,0.7295516952751605,0.13662314668544415,-0.3054426755723461,0.3338368679188049,9.319221279452668,0.038183571311803624,-0.15835117828187525,0.13662314668544415,0.9777064845725953,-0.20741160864294675,2.8822486170920705,0.18588511287864595,1.5257704412624165,0.3338368679188049,0.18588511287864595,0.0873892183509377,0.7791325831371873,-0.6963789999906698,3.1856632779554896,1.226473264687721,0.0873892183509377,0.43260728550341354,0.038183571311803624,-0.4033529535656676,2.579522168150364,1.0771410238516028,-0.7938272123275193,-0.4033529535656676,1.5257704412624165 3367 Skin rash 6 23 2.0129727697534303 0.0441174941008553 Q06136,P31040,P14174,Q14739,P28070,P21912 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,203,202,28,296,361 202,1559,654,361,2892,296,203,1388,2304,2949,1211,1297,2624,1220,3,2694,28,404,2045,2253,964,2513,2526 1.1766720264729662,0.038183571311803624,0.5809623580063942,0.8783698441961026,-0.7938272123275193,0.9777064845725953,1.1766720264729662,0.13662314668544415,-0.35441285400454997,-0.8425099767812463,0.23517487778404642,0.18588511287864595,-0.5499958789251567,0.23517487778404642,8.014833256953048,-0.5988187323015277,2.8822486170920705,0.8287386969157501,-0.20741160864294675,-0.3054426755723461,0.38320863530356236,-0.45226328736089716,-0.45226328736089716 3367 Branched chain amino acid catabolism 9 15 2.0051442738108647 0.0449476255080729 Q6NVY1,P09622,P24752,Q99714,Q96RQ3,O15382,Q9HCC0,P30084,P35610 Processes and pathways Reactome Pathways msigdb_reactome 678,593,656,971,765,851,630,485,927 851,593,920,1475,656,1383,485,1478,927,1927,1219,678,765,971,630 0.43260728550341354,0.6304663824403278,0.38320863530356236,0.0873892183509377,0.5809623580063942,0.13662314668544415,0.7295516952751605,0.0873892183509377,0.38320863530356236,-0.15835117828187525,0.23517487778404642,0.5809623580063942,0.5314843607251645,0.38320863530356236,0.6304663824403278 3367 Cellular response to acid chemical 7 16 1.990629237332161 0.0465216634814713 P42345,Q9UQB8,O43504,Q14103,P26358,Q9Y2Q5,Q6IAA8 Processes and pathways GO Biological process msigdb_gobp 488,35,72,105,538,61,406 1899,72,859,538,793,488,2301,1930,105,1853,406,3304,623,1613,35,61 -0.15835117828187525,1.7257565807765058,0.43260728550341354,0.6799962288254567,0.4820325991962496,0.7295516952751605,-0.35441285400454997,-0.15835117828187525,1.5757334188139989,-0.10926118080988163,0.8287386969157501,-1.810768611489318,0.6304663824403278,0.038183571311803624,2.579522168150364,1.9260951373543165 3367 Inner mitochondrial membrane organization 11 19 1.9844533154722053 0.0472053275115471 Q6UXV4,Q9BUR5,O94826,O75431,Q9Y5L4,Q9NVH1,Q9Y512,Q9H3K2,Q5XKP0,Q16891,Q9P0J0 Processes and pathways GO Biological process msigdb_gobp 614,39,918,916,44,320,322,260,340,818,777 1280,916,918,1633,1925,2908,818,951,340,614,1324,39,260,320,1260,777,2281,322,44 0.18588511287864595,0.38320863530356236,0.38320863530356236,-0.010993546587328921,-0.15835117828187525,-0.7938272123275193,0.4820325991962496,0.38320863530356236,0.9280258355715242,0.6304663824403278,0.18588511287864595,2.4284246073224494,1.0771410238516028,0.9777064845725953,0.23517487778404642,0.5314843607251645,-0.3054426755723461,0.9777064845725953,2.3277934623192205 3367 2 oxoglutarate dependent dioxygenase activity 7 17 1.9797258951075367 0.0477343371903296 P13674,O60568,Q9Y2K7,Q02809,Q32P28,Q6P6C2,P07237 Functions GO Molecular function msigdb_gomf 267,87,702,303,117,557,395 1084,1628,87,395,267,718,1106,303,1222,117,1681,557,956,2774,1439,702,2090 0.28449220643173684,-0.010993546587328921,1.625718868683733,0.8287386969157501,1.027411607598693,0.5314843607251645,0.28449220643173684,0.9777064845725953,0.23517487778404642,1.5257704412624165,-0.010993546587328921,0.6799962288254567,0.38320863530356236,-0.6476130114745601,0.13662314668544415,0.5809623580063942,-0.20741160864294675 3367 Mitochondrial small ribosomal subunit 7 16 1.9773035845666809 0.0480073247443908 Q9Y291,Q9NVS2,P82664,Q9Y3D3,Q9Y399,P82912,Q9Y2Q9 Localization GO Cellular component msigdb_gocc 477,577,159,213,523,302,122 865,3040,159,1940,1661,302,1662,939,1141,577,477,122,637,1080,523,213 0.43260728550341354,-0.9397941363276027,1.326146363804916,-0.15835117828187525,-0.010993546587328921,0.9777064845725953,-0.010993546587328921,0.38320863530356236,0.28449220643173684,0.6799962288254567,0.7791325831371873,1.5257704412624165,0.6304663824403278,0.3338368679188049,0.7295516952751605,1.1766720264729662 3367 Lower limb hypertonia 7 13 1.968834391755584 0.0489721115602814 P54886,P46100,P31040,Q9ULH0,Q14739,Q9NVV4,P21912 Drugs and Diseases Human Phenotype Ontology msigdb_hp 866,724,203,196,28,473,361 2197,361,203,1106,724,1932,866,28,1867,963,1878,473,196 -0.3054426755723461,0.8783698441961026,1.1766720264729662,0.28449220643173684,0.5314843607251645,-0.15835117828187525,0.43260728550341354,2.8822486170920705,-0.10926118080988163,0.38320863530356236,-0.10926118080988163,0.7791325831371873,1.226473264687721 3367 SLC superfamily of solute carriers 18 38 1.9639884026250247 0.04953143685101 P53007,P41440,P12236,Q9UBX3,O43772,Q8IXU6,Q9H2D1,Q70HW3,O75746,Q9Y6C9,Q9BSK2,Q9H0U3,P05141,P30825,Q9NZJ7,O95563,Q9HC21,P11166 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 333,33,397,580,7,42,179,10,425,45,52,467,534,330,100,329,164,396 2361,7,1549,425,1633,329,534,2462,396,1638,397,330,33,333,1653,731,606,545,2043,1584,3303,3153,1311,1229,10,42,1240,1062,52,467,179,2969,1341,164,100,580,1350,45 -0.4033529535656676,5.635301863617322,0.038183571311803624,0.7791325831371873,-0.010993546587328921,0.9280258355715242,0.6799962288254567,-0.45226328736089716,0.8287386969157501,-0.010993546587328921,0.8287386969157501,0.9280258355715242,2.579522168150364,0.9280258355715242,-0.010993546587328921,0.5314843607251645,0.6304663824403278,0.6799962288254567,-0.20741160864294675,0.038183571311803624,-1.810768611489318,-1.1340440384713235,0.18588511287864595,0.23517487778404642,5.275776405771673,2.378098897295108,0.23517487778404642,0.3338368679188049,2.026393700295174,0.7791325831371873,1.276298099702733,-0.8425099767812463,0.18588511287864595,1.326146363804916,1.625718868683733,0.6799962288254567,0.18588511287864595,2.3277934623192205 3367 Ketosis 11 20 1.9620005907342384 0.0497624154775722 Q92947,Q96RR1,P11182,P08574,P24752,P55809,P11310,Q9HCC0,Q4G176,P09001,P35610 Drugs and Diseases Human Phenotype Ontology msigdb_hp 761,509,920,592,656,438,29,630,820,201,927 1468,2286,592,201,920,29,1638,1475,1195,656,1383,927,1653,438,2632,820,761,1059,509,630 0.0873892183509377,-0.35441285400454997,0.6304663824403278,1.1766720264729662,0.38320863530356236,2.83174577665665,-0.010993546587328921,0.0873892183509377,0.23517487778404642,0.5809623580063942,0.13662314668544415,0.38320863530356236,-0.010993546587328921,0.7791325831371873,-0.5499958789251567,0.4820325991962496,0.5314843607251645,0.3338368679188049,0.7295516952751605,0.6304663824403278 3367