term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Vacuolar lumen 28 65 5.583912546639208 2.351669925753945e-08 O14773,Q9BTY2,P04066,Q9UM22,P15586,Q8NHP8,P07602,O00584,Q99538,P06280,P61916,P13473,Q14108,Q9NZJ7,P50897,O00462,P11117,O00754,P17900,P06865,Q8IV08,P54802,P10253,P10619,Q92820,P07686,Q13510,Q99536 Localization GO Cellular component msigdb_gocc 2,4,6,8,13,15,17,18,20,23,25,26,27,162,35,40,41,44,46,47,51,54,59,68,77,103,104,124 40,839,18,44,2,1301,2070,841,6,23,47,2986,1170,17,103,2158,59,68,41,2587,1571,26,413,13,164,46,844,1670,2802,1389,2168,596,2447,35,2997,1114,274,1929,54,2262,2370,25,1246,1485,1768,2268,3132,104,27,328,51,2196,15,77,2205,2555,124,20,4,1286,3142,1364,162,8,579 3.1081955602316613,0.3949453920319386,4.120355977593298,3.014617485988229,5.884770299255648,0.10496721166567786,-0.2810734678085235,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,-0.8637791771530676,0.18875209347989597,4.3750256940936305,1.719723884747831,-0.3248598804887178,2.4362503004565204,2.1690444425785262,3.077087184000687,-0.546410842239735,-0.022088097488964575,3.713721512871941,0.7933537558921767,4.896921049154351,1.3964785412072227,3.014617485988229,0.3949453920319386,-0.06480379588709152,-0.6814093200124656,0.06279828060143189,-0.3248598804887178,0.5964120554641071,-0.4572697498231123,3.2625005214835268,-0.8637791771530676,0.23036622014532987,1.0620389315076852,-0.1940306860173823,2.664757267155283,-0.36882191692968064,-0.412958796825298,3.772633277255873,0.14695211780225223,0.020446217421404334,-0.10770002139860704,-0.36882191692968064,-1.0488191777371687,1.719723884747831,3.6248188309031892,0.9478531474732188,2.7291839700941773,-0.3248598804887178,4.815860976496678,2.0670777141599412,-0.3248598804887178,-0.5017540153159744,1.613148049789865,3.9186948792031995,5.6569309364282425,0.14695211780225223,-1.0488191777371687,0.10496721166567786,1.4329258820598159,5.347423495313898,0.6361522503407359 3367 Lysosome 28 51 5.503573695581526 3.721688525877566e-08 O14773,O75503,P04066,P15586,P07602,Q99538,P06280,P61916,P13473,Q14108,Q9NZJ7,P50897,O00462,P11117,P16278,O00754,P17900,P06865,Q15904,P54802,P11717,P10253,Q8NCC3,P10619,O15118,P11279,P07686,Q13510 Processes and pathways KEGG Pathways msigdb_kegg 2,3,6,13,17,20,23,25,26,27,162,35,40,41,164,44,46,47,48,54,53,59,60,68,81,90,103,104 408,40,44,183,2,81,1301,959,3,841,6,23,47,17,103,412,1039,59,68,41,90,53,26,413,13,164,46,592,2168,35,274,54,972,737,25,796,1771,104,27,48,60,1515,923,20,1961,162,354,2840,2893,2324,1295 0.7933537558921767,3.1081955602316613,3.014617485988229,1.3231682601538646,5.884770299255648,2.032866242545018,0.10496721166567786,0.31303318522898527,5.682423722639393,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,0.7933537558921767,0.27179356591045745,2.4362503004565204,2.1690444425785262,3.077087184000687,1.8948765913387664,2.664757267155283,3.713721512871941,0.7933537558921767,4.896921049154351,1.3964785412072227,3.014617485988229,0.5964120554641071,-0.3248598804887178,3.2625005214835268,1.0620389315076852,2.664757267155283,0.31303318522898527,0.4760956266149155,3.772633277255873,0.4356160170646649,-0.10770002139860704,1.719723884747831,3.6248188309031892,2.888645998928826,2.3368292667835435,0.020446217421404334,0.3540841185619894,3.9186948792031995,-0.1940306860173823,1.4329258820598159,0.909473770504105,-0.6814093200124656,-0.7267490661171271,-0.36882191692968064,0.14695211780225223 3367 Lysosomal lumen 25 36 5.175364561715559 2.274663879028727e-07 O14773,P04066,Q9UM22,P15586,Q8NHP8,P07602,O00584,Q99538,P06280,P61916,P13473,Q14108,Q9NZJ7,P50897,O00462,P11117,O00754,P17900,P06865,Q8IV08,P54802,P10253,P10619,P07686,Q13510 Localization GO Cellular component msigdb_gocc 2,6,8,13,15,17,18,20,23,25,26,27,162,35,40,41,44,46,47,51,54,59,68,103,104 40,18,44,2,1301,841,6,23,47,17,103,2158,59,68,41,2587,26,413,13,164,46,1389,2168,596,35,54,25,104,27,51,2196,15,20,1286,162,8 3.1081955602316613,4.120355977593298,3.014617485988229,5.884770299255648,0.10496721166567786,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,-0.3248598804887178,2.4362503004565204,2.1690444425785262,3.077087184000687,-0.546410842239735,3.713721512871941,0.7933537558921767,4.896921049154351,1.3964785412072227,3.014617485988229,0.06279828060143189,-0.3248598804887178,0.5964120554641071,3.2625005214835268,2.664757267155283,3.772633277255873,1.719723884747831,3.6248188309031892,2.7291839700941773,-0.3248598804887178,4.815860976496678,3.9186948792031995,0.14695211780225223,1.4329258820598159,5.347423495313898 3367 Azurophil granule 23 68 4.821958406212878 1.4215559227537256e-06 Q9BTY2,P04066,P15586,P07602,O00584,P06280,P61916,P13473,Q92542,Q9NZJ7,P42785,O00462,O00754,P17900,P06865,O15260,P10253,P27105,P10619,Q92820,P11279,P07686,Q99536 Localization GO Cellular component msigdb_gocc 4,6,13,17,18,23,25,26,159,162,31,40,44,46,47,49,59,62,68,77,90,103,124 40,839,18,44,49,1103,1301,2426,300,3254,2070,6,23,47,2986,1170,17,103,59,68,1571,90,26,413,13,164,46,844,62,1670,2802,3067,31,2447,2997,3305,1927,1114,274,1929,2262,2370,25,1246,1485,1768,2268,1331,3132,328,420,690,2196,2758,159,77,1878,2205,2555,124,3188,4,1007,3142,1364,162,2412,579 3.1081955602316613,0.3949453920319386,4.120355977593298,3.014617485988229,2.793240616952005,0.23036622014532987,0.10496721166567786,-0.4572697498231123,0.9860724317343753,-1.378937844623164,-0.2810734678085235,5.477203395245907,3.860476447122193,2.9518057266228475,-0.8637791771530676,0.18875209347989597,4.3750256940936305,1.719723884747831,2.4362503004565204,2.1690444425785262,-0.022088097488964575,1.8948765913387664,3.713721512871941,0.7933537558921767,4.896921049154351,1.3964785412072227,3.014617485988229,0.3949453920319386,2.270032897213297,-0.06480379588709152,-0.6814093200124656,-0.9559681035265681,3.4450326941058216,-0.4572697498231123,-0.8637791771530676,-1.6681404132370228,-0.1940306860173823,0.23036622014532987,1.0620389315076852,-0.1940306860173823,-0.36882191692968064,-0.412958796825298,3.772633277255873,0.14695211780225223,0.020446217421404334,-0.10770002139860704,-0.36882191692968064,0.10496721166567786,-1.0488191777371687,0.9478531474732188,0.7933537558921767,0.51638636702171,-0.3248598804887178,-0.6362392226649662,1.4329258820598159,2.0670777141599412,-0.15077592925131486,-0.3248598804887178,-0.5017540153159744,1.613148049789865,-1.142327166182432,5.6569309364282425,0.31303318522898527,-1.0488191777371687,0.10496721166567786,1.4329258820598159,-0.412958796825298,0.6361522503407359 3367 Response of eif2ak4 gcn2 to amino acid deficiency 43 75 4.7432855288655205 2.1027955376951013e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,P08243,Q02543,P61927,P62910,P61513,P62241,Q9Y3U8,Q92616,P46776,P83881,P62888,P62266,P61247,P62750,P15880,P62753,P39023,P62861,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,323,208,220,219,247,218,345,102,238,108,232,231,230,229,363,360,119,118,364,366 2431,2797,2584,208,1230,2159,360,165,591,303,1751,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,293,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,134,238,102 -0.4572697498231123,-0.6814093200124656,-0.546410842239735,1.249292736644776,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.10770002139860704,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,1.1748381597601374,1.7549981936289338 3367 Cellular response to starvation 46 90 4.728946763730253 2.256875457851137e-06 Q9Y2Q5,P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,P08243,Q9UI12,Q02543,P61927,P61513,P62241,Q9Y3U8,Q92616,P42345,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 136,133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,323,208,354,220,219,218,345,102,238,107,108,232,231,230,229,364,363,360,119,118,247,366 1899,2431,2797,2584,208,1230,2159,360,165,591,303,1751,2348,2250,1833,70,1043,195,1315,595,969,3214,133,3177,3095,118,306,107,177,108,292,186,167,1113,178,3227,416,639,293,2087,851,229,910,74,275,737,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,134,690,1873,238,487,1967,354,136,102,2646 -0.1940306860173823,-0.4572697498231123,-0.6814093200124656,-0.546410842239735,1.249292736644776,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.10770002139860704,-0.412958796825298,-0.36882191692968064,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,-1.2364869532593843,1.5414559276361184,-1.142327166182432,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.6843250163853651,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,-0.2810734678085235,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.4760956266149155,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,0.51638636702171,-0.15077592925131486,1.1748381597601374,0.7150999985878068,-0.1940306860173823,0.909473770504105,1.5414559276361184,1.7549981936289338,-0.546410842239735 3367 Eukaryotic translation initiation 50 100 4.688939801949416 2.7462415457257805e-06 Q14152,Q04637,P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,P46778,P62829,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q9NR50,Q14232,P61927,P18124,P61513,P62241,Q9Y3U8,P62701,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P49770,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 368,515,133,134,139,140,389,276,275,155,293,292,165,167,416,178,177,303,188,306,186,550,70,198,74,197,195,323,220,492,605,219,591,218,345,102,471,108,232,231,230,229,364,363,470,360,119,118,247,366 1095,1102,1660,1304,2150,1168,2431,2797,2584,2432,1230,2159,2729,360,165,591,303,1751,1833,2252,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,470,293,2597,2368,1845,1241,1395,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,515,134,913,1492,368,605,2455,3302,1070,492,1012,1725,2230,102 0.23036622014532987,0.23036622014532987,-0.06480379588709152,0.10496721166567786,-0.3248598804887178,0.18875209347989597,-0.4572697498231123,-0.6814093200124656,-0.546410842239735,-0.4572697498231123,0.14695211780225223,-0.3248598804887178,-0.6362392226649662,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.10770002139860704,-0.15077592925131486,-0.36882191692968064,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,0.7150999985878068,1.0241336866990407,-0.546410842239735,-0.412958796825298,-0.15077592925131486,0.14695211780225223,0.06279828060143189,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,0.6757140740040977,1.5414559276361184,0.3540841185619894,0.020446217421404334,0.8709321917690549,0.5964120554641071,-0.4572697498231123,-1.6195456688999854,0.27179356591045745,0.7150999985878068,0.31303318522898527,-0.06480379588709152,-0.3248598804887178,1.7549981936289338 3367 Selenoamino acid metabolism 42 89 4.632851588427256 3.606630976760172e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,Q13155,P84098,Q02543,P61927,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,325,323,220,219,218,345,102,108,232,231,230,229,364,363,360,119,118,247,366 2650,956,2154,2797,2584,1310,1230,2159,2073,360,165,591,303,1833,1177,70,1043,195,1315,595,969,133,3095,118,306,1582,177,108,292,186,167,1113,178,3227,1392,416,639,2740,293,2174,1931,2449,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,134,2453,325,3158,1693,2040,1441,102 -0.5912394888767456,0.31303318522898527,-0.3248598804887178,-0.6814093200124656,-0.546410842239735,0.10496721166567786,0.14695211780225223,-0.3248598804887178,-0.2810734678085235,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,0.18875209347989597,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,-0.022088097488964575,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.06279828060143189,0.7933537558921767,0.5564909583357176,-0.6362392226649662,1.0241336866990407,-0.3248598804887178,-0.1940306860173823,-0.4572697498231123,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.4572697498231123,0.9478531474732188,-1.0954913801193207,-0.06480379588709152,-0.23746346936348223,0.06279828060143189,1.7549981936289338 3367 Ribosome 43 71 4.629856061988503 3.659200035643906e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q9UHA3,P61927,P62910,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62750,P15880,P62753,P39023,P62861,Q02878 Processes and pathways KEGG Pathways msigdb_kegg 133,134,139,140,389,276,275,155,293,292,165,167,416,178,177,303,188,306,186,70,198,74,197,195,323,220,496,219,247,218,345,102,108,232,231,230,229,363,360,119,118,364,366 2797,2584,1230,2159,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,293,851,229,910,74,275,218,219,1054,345,680,3072,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,134,496,102 -0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,0.7150999985878068,1.7549981936289338 3367 Cytosolic ribosome 40 78 4.598307514279572 4.259369853931716e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,P61927,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62750,P15880,P62753,P39023,P62910,Q02878 Localization GO Cellular component msigdb_gocc 133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,323,220,219,218,345,102,108,232,231,230,229,363,360,119,118,247,366 2431,2797,2584,1230,2159,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,293,1926,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,1597,155,232,323,220,366,134,1694,1132,1005,1887,2310,102 -0.4572697498231123,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,-0.1940306860173823,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,-0.022088097488964575,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.06480379588709152,0.23036622014532987,0.31303318522898527,-0.15077592925131486,-0.36882191692968064,1.7549981936289338 3367 Srp dependent cotranslational protein targeting to membrane 42 89 4.59273612423557 4.37472082603918e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P60059,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,P61927,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,139,140,389,276,275,155,293,292,168,165,167,178,177,303,188,306,186,70,198,74,197,195,323,220,219,218,345,102,108,232,231,230,229,364,363,360,119,118,247,366 785,2583,670,2797,2584,1665,1230,2159,360,165,591,303,1833,70,1043,195,1315,595,969,133,1836,3095,118,3067,306,177,1920,108,292,186,167,1113,178,3227,416,639,1321,293,168,1680,851,2178,1846,229,910,74,275,218,679,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,975,155,232,323,220,366,134,3101,1606,1724,102,2645 0.4356160170646649,-0.546410842239735,0.51638636702171,-0.6814093200124656,-0.546410842239735,-0.06480379588709152,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-0.15077592925131486,-1.0023112020703986,1.613148049789865,-0.9559681035265681,0.9860724317343753,1.3598932144259221,-0.1940306860173823,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,0.10496721166567786,1.0241336866990407,1.3964785412072227,-0.06480379588709152,0.3949453920319386,-0.3248598804887178,-0.15077592925131486,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,0.51638636702171,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,0.31303318522898527,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-1.0023112020703986,-0.022088097488964575,-0.06480379588709152,1.7549981936289338,-0.546410842239735 3367 Cytosolic large ribosomal subunit 30 47 4.544604874021161 5.50383994601944e-06 P36578,Q07020,P63173,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P42766,P18621,P62917,P40429,P46778,P62899,P61313,P27635,P84098,Q02543,P61927,P61513,Q9Y3U8,P46776,P83881,P62888,P62750,P39023,P62910,Q02878 Localization GO Cellular component msigdb_gocc 133,134,140,276,275,155,293,292,165,167,177,303,188,306,186,198,74,195,323,220,219,218,102,108,232,231,363,118,247,366 2797,2584,165,591,303,1043,195,1315,595,969,133,118,306,177,108,292,186,167,416,639,293,1926,910,74,275,218,219,276,363,550,231,198,1244,247,2264,188,140,155,232,323,220,366,134,1694,1887,2310,102 -0.6814093200124656,-0.546410842239735,1.3964785412072227,0.5964120554641071,0.9860724317343753,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.7933537558921767,0.5564909583357176,1.0241336866990407,-0.1940306860173823,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,1.0620389315076852,0.8709321917690549,0.6361522503407359,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.06480379588709152,-0.15077592925131486,-0.36882191692968064,1.7549981936289338 3367 Eukaryotic translation elongation 41 76 4.499686164900425 6.8053858548466906e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,P61927,P62910,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62750,P15880,P62753,P39023,P62861,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,323,220,219,247,218,345,102,108,232,231,230,229,363,360,119,118,364,366 2797,2584,1230,2159,1312,360,165,591,303,1833,2857,70,1043,2256,195,2734,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,293,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,2813,134,102 -0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.10496721166567786,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,-0.7267490661171271,2.1351656880009666,0.27179356591045745,-0.36882191692968064,1.2863020037686608,-0.6362392226649662,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,-0.6814093200124656,1.5414559276361184,1.7549981936289338 3367 Nonsense mediated decay nmd 42 87 4.463044569290529 8.080323733894446e-06 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,P61927,Q96Q15,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,323,220,219,94,218,345,102,108,232,231,230,229,364,363,360,119,118,247,366 2797,2584,1230,2159,2729,3194,360,165,591,303,1833,70,1043,195,1315,2164,595,969,133,2593,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,293,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,2743,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,2265,140,155,232,323,220,366,515,134,2372,804,1267,560,1876,94,1534,1213,102,2418 -0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,-0.6362392226649662,-1.1893259001279373,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,-0.3248598804887178,0.5964120554641071,0.31303318522898527,1.5414559276361184,-0.546410842239735,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,-0.6362392226649662,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,-0.36882191692968064,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,0.6757140740040977,1.5414559276361184,-0.412958796825298,0.4356160170646649,0.14695211780225223,0.6361522503407359,-0.15077592925131486,1.8948765913387664,0.020446217421404334,0.18875209347989597,1.7549981936289338,-0.412958796825298 3367 Splenomegaly 18 95 4.401985565291103 1.072646948596656e-05 Q15392,Q658P3,P04066,Q14739,Q13510,P10253,P16278,O00754,P15586,Q15904,P07602,O15118,P01889,P54802,Q9NZJ7,P61916,Q14108,P14174 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,36,6,38,104,59,164,44,13,48,17,81,84,54,162,25,27,116 408,357,44,183,1974,81,3211,2651,1228,2652,724,3173,2903,1825,84,3148,841,6,1463,2582,1378,2157,3193,17,59,466,1231,2342,2990,1572,790,116,13,164,1174,2907,2348,1752,1575,2800,2860,258,2352,1318,1999,2259,2168,906,597,735,2363,307,2007,2175,54,1240,25,1685,1185,2268,1772,1600,104,1058,27,38,0,1860,2459,420,48,476,36,2822,377,3047,1203,2548,1273,2622,2930,2476,1523,1353,816,1530,530,1007,1361,2631,2134,944,162,2490,2942 0.7933537558921767,0.8709321917690549,3.014617485988229,1.3231682601538646,-0.23746346936348223,2.032866242545018,-1.2364869532593843,-0.5912394888767456,0.14695211780225223,-0.5912394888767456,0.4760956266149155,-1.142327166182432,-0.7722577547913748,-0.15077592925131486,1.9985415804284918,-1.0954913801193207,0.3949453920319386,5.477203395245907,0.020446217421404334,-0.546410842239735,0.06279828060143189,-0.3248598804887178,-1.1893259001279373,4.3750256940936305,2.4362503004565204,0.7150999985878068,0.14695211780225223,-0.412958796825298,-0.8637791771530676,-0.022088097488964575,0.4356160170646649,1.613148049789865,4.896921049154351,1.3964785412072227,0.18875209347989597,-0.7722577547913748,-0.412958796825298,-0.10770002139860704,-0.022088097488964575,-0.6814093200124656,-0.7267490661171271,1.099790142352336,-0.412958796825298,0.10496721166567786,-0.23746346936348223,-0.36882191692968064,-0.3248598804887178,0.3540841185619894,0.5964120554641071,0.4760956266149155,-0.412958796825298,0.9860724317343753,-0.23746346936348223,-0.3248598804887178,2.664757267155283,0.14695211780225223,3.772633277255873,-0.06480379588709152,0.18875209347989597,-0.36882191692968064,-0.10770002139860704,-0.022088097488964575,1.719723884747831,0.27179356591045745,3.6248188309031892,3.1701628794451158,9.266342596549883,-0.15077592925131486,-0.4572697498231123,0.7933537558921767,2.888645998928826,0.7150999985878068,3.201023198065498,-0.6814093200124656,0.8709321917690549,-0.9097905400273109,0.18875209347989597,-0.5017540153159744,0.14695211780225223,-0.546410842239735,-0.7722577547913748,-0.4572697498231123,0.020446217421404334,0.10496721166567786,0.4356160170646649,0.020446217421404334,0.6757140740040977,0.31303318522898527,0.10496721166567786,-0.546410842239735,-0.2810734678085235,0.3540841185619894,1.4329258820598159,-0.4572697498231123,-0.7722577547913748 3367 Structural constituent of ribosome 48 113 4.26422254784621 2.0059943288908144e-05 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,Q9Y3D3,P40429,P46778,Q9BYC9,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q5T653,Q9UHA3,P61927,P61513,P62241,Q9Y3U8,Q9NVS2,P46776,P83881,P62888,P62266,P61247,Q9P015,P62750,P15880,P62753,P39023,P09001,P62910,Q02878 Functions GO Molecular function msigdb_gomf 133,134,139,140,389,276,275,155,293,292,165,167,416,178,177,303,188,455,306,186,204,70,198,74,197,195,323,220,221,496,219,218,345,102,242,108,232,231,230,229,386,363,360,119,118,359,247,366 1906,2797,2584,1230,2159,359,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,1922,293,2171,3070,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,3180,1684,3000,2267,1597,2014,1850,155,232,323,220,366,134,2017,3159,221,1694,692,871,1787,3077,2388,2298,2700,204,1433,1887,1212,2561,1152,941,1536,3207,242,386,496,1728,662,1654,1819,716,2784,455,1223,102 -0.1940306860173823,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-0.3248598804887178,-0.9559681035265681,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,-1.142327166182432,-0.06480379588709152,-0.8637791771530676,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,-0.15077592925131486,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.23746346936348223,-1.0954913801193207,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,-0.10770002139860704,-0.9559681035265681,-0.412958796825298,-0.36882191692968064,-0.5912394888767456,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.18875209347989597,-0.5017540153159744,0.23036622014532987,0.3540841185619894,0.020446217421404334,-1.1893259001279373,1.1748381597601374,0.8709321917690549,0.7150999985878068,-0.06480379588709152,0.5564909583357176,-0.022088097488964575,-0.10770002139860704,0.51638636702171,-0.6362392226649662,0.754312439228042,0.18875209347989597,1.7549981936289338 3367 Ribosomal protein 47 107 4.175479253574338 2.9735935493713228e-05 Q07020,P62841,P63173,Q8TDN6,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P47914,P46782,P42766,O76021,P62917,Q9Y3D3,O00541,P40429,P55769,P46778,Q9BYC9,P62829,P25398,P62899,P61313,P62847,P27635,P84098,Q5T653,Q9UHA3,P61927,P18124,P62241,Q9Y3U8,Q9NVS2,P62701,P46776,P83881,P62888,P62266,P62750,P15880,P62753,P39023,P62910,Q02878 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 134,139,140,422,276,275,155,293,292,165,167,416,178,177,539,188,455,535,306,63,186,204,550,70,198,74,197,195,323,221,496,219,591,345,102,242,471,108,232,231,230,363,360,119,118,247,366 535,1661,1457,539,1230,2159,360,165,591,1833,70,1043,195,1315,2441,1179,595,969,3095,118,306,177,108,292,186,167,1113,178,3227,416,1922,293,2171,1394,3070,63,1591,851,910,74,275,219,1054,345,680,854,230,1594,794,795,276,471,363,119,550,139,197,1681,231,198,1244,247,2264,188,140,681,3000,2267,1597,155,232,323,366,134,2867,2017,860,1336,3159,221,1694,692,871,1201,3077,422,2200,995,2700,1710,204,1433,1887,941,1361,3207,2218,242,2134,2634,496,1819,716,2896,2784,455,102 0.6361522503407359,-0.06480379588709152,0.020446217421404334,0.6361522503407359,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,-0.4572697498231123,0.18875209347989597,0.5964120554641071,0.31303318522898527,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,-0.1940306860173823,1.0241336866990407,-0.3248598804887178,0.06279828060143189,-0.9559681035265681,2.2364769766120918,-0.022088097488964575,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,0.51638636702171,-0.8637791771530676,-0.36882191692968064,-0.022088097488964575,1.4329258820598159,1.1748381597601374,0.9478531474732188,0.8709321917690549,1.5414559276361184,-0.7267490661171271,-0.23746346936348223,0.3949453920319386,0.10496721166567786,-1.0954913801193207,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,0.18875209347989597,-0.9559681035265681,0.7933537558921767,-0.3248598804887178,0.31303318522898527,-0.5912394888767456,-0.06480379588709152,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.3540841185619894,0.10496721166567786,-1.1893259001279373,-0.3248598804887178,1.1748381597601374,-0.2810734678085235,-0.546410842239735,0.7150999985878068,-0.10770002139860704,0.51638636702171,-0.7267490661171271,-0.6362392226649662,0.754312439228042,1.7549981936289338 3367 Abnormal circulating cholesterol concentration 9 33 4.144573651457248 3.404465247247579e-05 Q15392,Q9UBM7,P42858,Q14739,Q15125,Q15904,P07602,P61916,P37268 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,1,100,38,7,48,17,25,30 1980,3148,1169,17,1579,30,2168,100,3178,1840,1482,2520,25,1183,912,1774,1123,38,7,0,2024,446,48,1343,920,421,1873,1270,2209,2633,162,1,2567 -0.23746346936348223,-1.0954913801193207,0.18875209347989597,4.3750256940936305,-0.022088097488964575,3.4751842548839553,-0.3248598804887178,1.7549981936289338,-1.142327166182432,-0.15077592925131486,0.020446217421404334,-0.5017540153159744,3.772633277255873,0.18875209347989597,0.3540841185619894,-0.10770002139860704,0.23036622014532987,3.1701628794451158,5.347423495313898,9.266342596549883,-0.23746346936348223,0.754312439228042,2.888645998928826,0.10496721166567786,0.3540841185619894,0.7933537558921767,-0.15077592925131486,0.14695211780225223,-0.3248598804887178,-0.546410842239735,1.4329258820598159,6.354521266861696,-0.5017540153159744 3367 Cytoplasmic ribosomal proteins 41 74 4.144433555554718 3.406547084905398e-05 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,P61927,P62910,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62750,P15880,P62753,P39023,P62861,Q02878 Processes and pathways WikiPathways msigdb_wp 133,134,139,140,389,276,275,155,293,292,165,167,178,177,303,188,306,186,70,198,74,197,195,323,220,219,247,218,345,102,108,232,231,230,229,363,360,119,118,364,366 2797,2584,1230,2159,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,1922,293,3352,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,134,3355,102 -0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-2.6721680762670923,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-2.77585155562055,1.7549981936289338 3367 Azurophil granule lumen 12 42 4.118279642929749 3.817113267445826e-05 Q9BTY2,P10619,P04066,P07686,O00754,P15586,P17900,Q92820,O00584,Q99536,P06280,P61916 Localization GO Cellular component msigdb_gocc 4,68,6,103,44,13,46,77,18,124,23,25 839,18,44,1301,2070,6,23,2986,1170,103,68,1571,413,13,164,46,844,1670,2802,2447,2997,1114,274,1929,2262,2370,25,1246,1485,1768,2268,3132,328,2196,77,2205,2555,124,4,3142,1364,579 0.3949453920319386,4.120355977593298,3.014617485988229,0.10496721166567786,-0.2810734678085235,5.477203395245907,3.860476447122193,-0.8637791771530676,0.18875209347989597,1.719723884747831,2.1690444425785262,-0.022088097488964575,0.7933537558921767,4.896921049154351,1.3964785412072227,3.014617485988229,0.3949453920319386,-0.06480379588709152,-0.6814093200124656,-0.4572697498231123,-0.8637791771530676,0.23036622014532987,1.0620389315076852,-0.1940306860173823,-0.36882191692968064,-0.412958796825298,3.772633277255873,0.14695211780225223,0.020446217421404334,-0.10770002139860704,-0.36882191692968064,-1.0488191777371687,0.9478531474732188,-0.3248598804887178,2.0670777141599412,-0.3248598804887178,-0.5017540153159744,1.613148049789865,5.6569309364282425,-1.0488191777371687,0.10496721166567786,0.6361522503407359 3367 Large ribosomal subunit 35 77 4.115196378232152 3.868499151615801e-05 P36578,Q07020,P63173,P62424,P61353,P83731,P50914,P46777,P18077,P46779,P42766,P18621,P62917,P40429,P46778,Q9BYC9,P62899,P61313,P27635,P84098,Q02543,Q5T653,P61927,Q567V2,P61513,Q9Y3U8,Q9NVS2,P46776,P83881,P62888,Q9P015,P62750,P39023,P09001,P62910 Localization GO Cellular component msigdb_gocc 133,134,140,276,275,155,293,292,165,167,177,303,188,306,186,204,198,74,195,323,220,221,219,93,218,102,242,108,232,231,386,363,118,359,247 2797,2584,359,165,591,303,1043,195,1315,595,969,133,118,306,177,108,292,186,167,416,639,1922,293,1926,3070,910,74,275,218,219,276,363,550,231,198,1244,247,2264,188,140,155,232,323,220,366,134,2017,3043,3159,93,221,1694,692,871,1787,2614,3077,2388,2700,2828,1710,1283,204,1433,1887,1212,2561,1152,941,2310,1536,3207,242,2223,386,2784,102 -0.6814093200124656,-0.546410842239735,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-0.1940306860173823,-0.9559681035265681,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,1.0620389315076852,0.8709321917690549,0.6361522503407359,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.23746346936348223,-0.9097905400273109,-1.0954913801193207,1.8948765913387664,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,-0.10770002139860704,-0.546410842239735,-0.9559681035265681,-0.412958796825298,-0.5912394888767456,-0.6814093200124656,-0.06480379588709152,0.14695211780225223,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.18875209347989597,-0.5017540153159744,0.23036622014532987,0.3540841185619894,-0.36882191692968064,0.020446217421404334,-1.1893259001279373,1.1748381597601374,-0.3248598804887178,0.8709321917690549,-0.6362392226649662,1.7549981936289338 3367 Ribosomal subunit 49 123 4.074786717836155 4.605653784972574e-05 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P82664,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,P46778,Q9BYC9,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q5T653,P61927,Q567V2,P61513,P62241,Q9Y3U8,Q9NVS2,P46776,P83881,P62888,P62266,P61247,Q9P015,P62750,P09001,P15880,P62753,P39023,P63244,P62910,Q02878 Localization GO Cellular component msigdb_gocc 133,134,139,140,389,276,275,155,278,293,292,165,167,416,178,177,303,188,306,186,204,70,198,74,197,195,323,220,221,219,93,218,345,102,242,108,232,231,230,229,386,363,359,360,119,118,248,247,366 2431,2797,2584,1230,2159,359,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,1922,293,1926,2171,3070,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,248,3180,278,3000,2267,1597,2014,1850,155,232,323,220,366,134,2017,3043,3159,93,221,1694,692,871,1132,1787,2614,3077,2388,2200,2700,2828,1710,1283,1005,204,1433,1887,1212,2561,1152,941,2310,1536,3207,242,2223,386,1728,662,1654,1819,716,2784,455,102 -0.4572697498231123,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-0.1940306860173823,-0.3248598804887178,-0.9559681035265681,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.1373892537486945,-1.142327166182432,1.0620389315076852,-0.8637791771530676,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,-0.15077592925131486,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.23746346936348223,-0.9097905400273109,-1.0954913801193207,1.8948765913387664,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,0.23036622014532987,-0.10770002139860704,-0.546410842239735,-0.9559681035265681,-0.412958796825298,-0.3248598804887178,-0.5912394888767456,-0.6814093200124656,-0.06480379588709152,0.14695211780225223,0.31303318522898527,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.18875209347989597,-0.5017540153159744,0.23036622014532987,0.3540841185619894,-0.36882191692968064,0.020446217421404334,-1.1893259001279373,1.1748381597601374,-0.3248598804887178,0.8709321917690549,-0.06480379588709152,0.5564909583357176,-0.022088097488964575,-0.10770002139860704,0.51638636702171,-0.6362392226649662,0.754312439228042,1.7549981936289338 3367 Ribosomal protein 48 121 4.067861139703758 4.7446640120796246e-05 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P82664,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,P46778,Q9BYC9,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q5T653,P61927,P61513,P62241,Q9Y3U8,Q9NVS2,P46776,P83881,P62888,P62266,P61247,Q9P015,P62750,P09001,P15880,P62753,P39023,P63244,P62910,Q02878 Functions Protein Atlas Molecular function protein_atlas_molecular_function 133,134,139,140,389,276,275,155,278,293,292,165,167,416,178,177,303,188,306,186,204,70,198,74,197,195,323,220,221,219,218,345,102,242,108,232,231,230,229,386,363,359,360,119,118,248,247,366 2797,2584,1230,2159,359,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,1922,293,2171,3070,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,248,3180,1684,278,3000,2267,1597,2014,1850,155,232,323,220,366,134,2017,3043,3159,221,1694,692,871,1787,2614,3077,2295,2388,2200,2298,2700,2828,1424,1710,204,1433,1887,1212,2561,1152,941,1536,3207,242,2223,386,1728,662,1654,1819,716,2784,455,1223,102 -0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-0.3248598804887178,-0.9559681035265681,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.1373892537486945,-1.142327166182432,-0.06480379588709152,1.0620389315076852,-0.8637791771530676,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,-0.15077592925131486,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.23746346936348223,-0.9097905400273109,-1.0954913801193207,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,-0.10770002139860704,-0.546410842239735,-0.9559681035265681,-0.36882191692968064,-0.412958796825298,-0.3248598804887178,-0.36882191692968064,-0.5912394888767456,-0.6814093200124656,0.06279828060143189,-0.06480379588709152,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.18875209347989597,-0.5017540153159744,0.23036622014532987,0.3540841185619894,0.020446217421404334,-1.1893259001279373,1.1748381597601374,-0.3248598804887178,0.8709321917690549,-0.06480379588709152,0.5564909583357176,-0.022088097488964575,-0.10770002139860704,0.51638636702171,-0.6362392226649662,0.754312439228042,0.18875209347989597,1.7549981936289338 3367 ribosomal protein 47 121 3.9969867504458834 6.415389029656993e-05 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P82664,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,P55769,P46778,Q9BYC9,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q5T653,P61927,P62241,Q9Y3U8,Q9NVS2,P46776,P83881,P62888,P62266,P61247,Q9P015,P62750,P15880,P62753,P39023,P09001,P62910,Q02878 Functions Panther Protein class panther_protein_class 133,134,139,140,389,276,275,155,278,293,292,165,167,416,178,177,303,188,306,63,186,204,70,198,74,197,195,323,220,221,219,345,102,242,108,232,231,230,229,386,363,360,119,118,359,247,366 539,2797,2584,1230,2159,359,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,1922,293,2171,3070,63,851,229,910,74,275,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,3180,1684,278,3000,2267,1597,2014,1850,155,232,323,220,366,134,2017,860,1336,3159,221,1694,692,871,1787,2614,3077,2388,2200,2298,2700,1710,1283,204,1433,1887,1212,2561,941,1536,3207,3143,242,2134,386,496,1728,662,1654,1819,716,2784,455,1223,102 0.6361522503407359,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-0.3248598804887178,-0.9559681035265681,2.2364769766120918,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,-1.142327166182432,-0.06480379588709152,1.0620389315076852,-0.8637791771530676,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,-0.15077592925131486,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.23746346936348223,0.3949453920319386,0.10496721166567786,-1.0954913801193207,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,-0.10770002139860704,-0.546410842239735,-0.9559681035265681,-0.412958796825298,-0.3248598804887178,-0.36882191692968064,-0.5912394888767456,-0.06480379588709152,0.14695211780225223,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.18875209347989597,-0.5017540153159744,0.3540841185619894,0.020446217421404334,-1.1893259001279373,-1.0488191777371687,1.1748381597601374,-0.2810734678085235,0.8709321917690549,0.7150999985878068,-0.06480379588709152,0.5564909583357176,-0.022088097488964575,-0.10770002139860704,0.51638636702171,-0.6362392226649662,0.754312439228042,0.18875209347989597,1.7549981936289338 3367 Hydrolase activity acting on glycosyl bonds 12 33 3.979990388372316 6.891805464737111e-05 O75503,Q9BTY2,P04066,P07686,O00462,P16278,O00754,P17900,P06865,P54802,P06280,P10253 Functions GO Molecular function msigdb_gomf 3,4,6,103,40,164,44,46,47,54,23,59 40,44,2144,783,2946,3,841,6,23,47,103,59,1987,163,164,46,1833,304,2076,440,54,1933,2091,1494,2021,1944,1412,2692,3350,4,2130,2838,2490 3.1081955602316613,3.014617485988229,-0.3248598804887178,0.4356160170646649,-0.8179346882917339,5.682423722639393,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,1.719723884747831,2.4362503004565204,-0.23746346936348223,1.3964785412072227,1.3964785412072227,3.014617485988229,-0.15077592925131486,0.9860724317343753,-0.2810734678085235,0.754312439228042,2.664757267155283,-0.1940306860173823,-0.2810734678085235,0.020446217421404334,-0.23746346936348223,-0.1940306860173823,0.06279828060143189,-0.5912394888767456,-2.5690694619563796,5.6569309364282425,-0.2810734678085235,-0.6814093200124656,-0.4572697498231123 3367 Cytoplasmic translation 46 116 3.96634476180264 7.298327285965023e-05 Q14152,P36578,Q07020,P62841,P63173,P67809,P62851,P62424,P61353,P83731,P50914,P46777,P18077,P46779,Q00839,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,P61927,P61513,P62241,Q9Y3U8,Q9ULC4,P42345,P46776,P83881,P62888,P62266,P61247,P62750,P15880,P62753,P39023,P16989,P62910,Q02878 Processes and pathways GO Biological process msigdb_gobp 368,133,134,139,140,147,389,276,275,155,293,292,165,167,179,178,177,303,188,306,186,70,198,74,197,195,323,220,219,218,345,102,243,107,108,232,231,230,229,363,360,119,118,117,247,366 1102,2900,1457,1227,2427,2797,2584,1230,2159,2729,1829,3194,360,117,165,591,303,1751,1833,2252,70,1043,195,1315,595,969,133,3095,118,306,1916,107,177,108,292,186,167,1113,178,3227,416,639,2913,293,2597,600,1845,1395,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,2743,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,147,155,232,323,179,220,366,515,2182,134,1488,1492,859,368,2455,3302,1070,1132,1789,1874,3107,2042,822,2773,2306,2307,3318,492,2891,3167,243,2057,102,2233 0.23036622014532987,-0.7722577547913748,0.020446217421404334,0.14695211780225223,-0.4572697498231123,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,-0.6362392226649662,-0.15077592925131486,-1.1893259001279373,0.8709321917690549,1.613148049789865,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.10770002139860704,-0.15077592925131486,-0.36882191692968064,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,-0.1940306860173823,1.6843250163853651,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.7722577547913748,1.0241336866990407,-0.546410842239735,0.5964120554641071,-0.15077592925131486,0.06279828060143189,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,-0.6362392226649662,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.469236846394831,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.3598932144259221,1.212138715175788,0.8709321917690549,0.6757140740040977,-0.3248598804887178,1.5414559276361184,0.020446217421404334,0.020446217421404334,0.3949453920319386,0.8709321917690549,-0.4572697498231123,-1.6195456688999854,0.27179356591045745,0.23036622014532987,-0.10770002139860704,-0.15077592925131486,-1.0023112020703986,-0.23746346936348223,0.4356160170646649,-0.6362392226649662,-0.36882191692968064,-0.36882191692968064,-1.7657985305992057,0.7150999985878068,-0.7267490661171271,-1.0954913801193207,1.1748381597601374,-0.23746346936348223,1.7549981936289338,-0.3248598804887178 3367 Protease 20 120 3.963360222786407 7.390214072144907e-05 O14773,Q9HB40,Q5BJF2,P42574,Q8NHP8,Q70CQ2,P42892,Q9H3G5,Q99538,P42785,Q9UIQ6,P02786,Q9UPT9,P10619,Q01804,Q92820,P08243,Q2T9J0,Q13510,P61247 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 2,9,10,260,15,280,16,19,20,31,32,67,205,68,71,77,208,92,104,229 1095,3061,1737,2574,2,1660,1562,1456,1982,1904,1032,437,67,2586,208,68,2344,790,2160,542,1992,1313,844,1832,2856,1044,2801,2352,1478,1579,1581,260,1917,31,16,2739,2595,2170,1238,2448,2006,1587,274,2175,2663,1844,2178,229,2599,975,71,3073,1599,1772,2453,104,392,1777,2672,1942,1062,2099,92,1501,1503,10,2461,2821,2382,375,989,280,2879,1615,2285,1134,1869,1348,15,2197,2198,1954,3107,1955,77,1516,2621,2201,1877,2204,2973,2701,1632,1880,2479,2208,2480,20,1281,1640,19,531,9,704,1894,2222,944,2891,1157,3209,1814,32,3325,205,2139,717,663,2493,2644,1551 0.23036622014532987,-0.9559681035265681,-0.10770002139860704,-0.546410842239735,5.884770299255648,-0.06480379588709152,-0.022088097488964575,0.020446217421404334,-0.23746346936348223,-0.1940306860173823,0.27179356591045745,0.754312439228042,2.202814512277326,-0.546410842239735,1.249292736644776,2.1690444425785262,-0.412958796825298,0.4356160170646649,-0.3248598804887178,0.6361522503407359,-0.23746346936348223,0.10496721166567786,0.3949453920319386,-0.15077592925131486,-0.7267490661171271,0.27179356591045745,-0.6814093200124656,-0.412958796825298,0.020446217421404334,-0.022088097488964575,-0.022088097488964575,1.099790142352336,-0.1940306860173823,3.4450326941058216,4.4588127644301565,-0.6362392226649662,-0.546410842239735,-0.3248598804887178,0.14695211780225223,-0.4572697498231123,-0.23746346936348223,-0.022088097488964575,1.0620389315076852,-0.3248598804887178,-0.5912394888767456,-0.15077592925131486,-0.3248598804887178,1.1748381597601374,-0.546410842239735,0.31303318522898527,2.1351656880009666,-0.9559681035265681,-0.022088097488964575,-0.10770002139860704,-0.4572697498231123,1.719723884747831,0.8322262551325478,-0.10770002139860704,-0.5912394888767456,-0.1940306860173823,0.27179356591045745,-0.2810734678085235,1.8948765913387664,0.020446217421404334,0.020446217421404334,5.216435956950591,-0.4572697498231123,-0.6814093200124656,-0.412958796825298,0.8709321917690549,0.31303318522898527,1.0620389315076852,-0.7267490661171271,-0.022088097488964575,-0.36882191692968064,0.23036622014532987,-0.15077592925131486,0.10496721166567786,4.815860976496678,-0.3248598804887178,-0.3248598804887178,-0.1940306860173823,-1.0023112020703986,-0.1940306860173823,2.0670777141599412,0.020446217421404334,-0.546410842239735,-0.3248598804887178,-0.15077592925131486,-0.3248598804887178,-0.8179346882917339,-0.5912394888767456,-0.022088097488964575,-0.15077592925131486,-0.4572697498231123,-0.3248598804887178,-0.4572697498231123,3.9186948792031995,0.14695211780225223,-0.022088097488964575,3.9766430116579654,0.6757140740040977,5.321323717121585,0.51638636702171,-0.15077592925131486,-0.3248598804887178,0.3540841185619894,-0.7267490661171271,0.23036622014532987,-1.1893259001279373,-0.10770002139860704,3.354118052447859,-1.8640777914925752,1.2863020037686608,-0.2810734678085235,0.51638636702171,0.5564909583357176,-0.4572697498231123,-0.546410842239735,0.020446217421404334 3367 Peptidase activity 23 118 3.954418959042053 7.672087047994047e-05 O14773,Q9HB40,P42574,Q70CQ2,P42892,Q9H3G5,Q99538,Q6P2Q9,Q92542,Q96DE0,P53634,P28072,P42785,Q9UIQ6,O75976,Q9NUQ7,P02786,Q9UPT9,P10619,Q01804,Q92820,Q2T9J0,Q9UPU5 Functions GO Molecular function msigdb_gomf 2,9,260,280,16,19,20,149,159,28,274,272,31,32,45,315,67,205,68,71,77,92,244 1095,1737,2,1660,1562,1982,1904,45,2500,1032,437,67,2156,2586,2854,68,790,2160,542,1992,504,2856,674,2860,272,1577,2801,2352,2735,1999,1581,260,1917,31,16,2739,2595,1924,2359,907,1238,2448,2006,1587,274,2663,1844,1242,2178,975,365,2090,71,1772,3098,1600,392,2672,3101,2532,92,2604,1503,2461,2821,2382,989,1786,149,280,2879,1615,2285,1415,1869,1073,1954,159,1955,77,1273,1516,311,1877,2929,28,2973,1276,1632,1880,2479,2208,1431,1280,2480,20,3188,932,1640,19,1151,531,1809,9,2048,2709,315,2222,944,1157,3209,32,205,244,717,663,2493,2644 0.23036622014532987,-0.10770002139860704,5.884770299255648,-0.06480379588709152,-0.022088097488964575,-0.23746346936348223,-0.1940306860173823,3.014617485988229,-0.5017540153159744,0.27179356591045745,0.754312439228042,2.202814512277326,-0.3248598804887178,-0.546410842239735,-0.7267490661171271,2.1690444425785262,0.4356160170646649,-0.3248598804887178,0.6361522503407359,-0.23746346936348223,0.6757140740040977,-0.7267490661171271,0.51638636702171,-0.7267490661171271,1.0620389315076852,-0.022088097488964575,-0.6814093200124656,-0.412958796825298,-0.6362392226649662,-0.23746346936348223,-0.022088097488964575,1.099790142352336,-0.1940306860173823,3.4450326941058216,4.4588127644301565,-0.6362392226649662,-0.546410842239735,-0.1940306860173823,-0.412958796825298,0.3540841185619894,0.14695211780225223,-0.4572697498231123,-0.23746346936348223,-0.022088097488964575,1.0620389315076852,-0.5912394888767456,-0.15077592925131486,0.14695211780225223,-0.3248598804887178,0.31303318522898527,0.8709321917690549,-0.2810734678085235,2.1351656880009666,-0.10770002139860704,-1.0023112020703986,-0.022088097488964575,0.8322262551325478,-0.5912394888767456,-1.0023112020703986,-0.5017540153159744,1.8948765913387664,-0.546410842239735,0.020446217421404334,-0.4572697498231123,-0.6814093200124656,-0.412958796825298,0.31303318522898527,-0.10770002139860704,1.469236846394831,1.0620389315076852,-0.7267490661171271,-0.022088097488964575,-0.36882191692968064,0.06279828060143189,-0.15077592925131486,0.27179356591045745,-0.1940306860173823,1.4329258820598159,-0.1940306860173823,2.0670777141599412,0.14695211780225223,0.020446217421404334,0.9860724317343753,-0.15077592925131486,-0.7722577547913748,3.535260987655072,-0.8179346882917339,0.14695211780225223,-0.022088097488964575,-0.15077592925131486,-0.4572697498231123,-0.3248598804887178,0.06279828060143189,0.14695211780225223,-0.4572697498231123,3.9186948792031995,-1.142327166182432,0.3540841185619894,-0.022088097488964575,3.9766430116579654,0.23036622014532987,0.6757140740040977,-0.10770002139860704,5.321323717121585,-0.23746346936348223,-0.5912394888767456,0.9860724317343753,-0.3248598804887178,0.3540841185619894,0.23036622014532987,-1.1893259001279373,3.354118052447859,1.2863020037686608,1.1748381597601374,0.51638636702171,0.5564909583357176,-0.4572697498231123,-0.546410842239735 3367 Ribosomal proteins 51 129 3.919305323326885 8.880455802140474e-05 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P82664,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,O95478,P55769,P46778,Q9BYC9,P25398,P62899,P61313,P62847,P27635,P78345,P84098,Q02543,Q5T653,P61927,P61513,P62241,Q9Y3U8,Q9NVS2,P46776,P83881,P62888,P62266,P61247,Q9P015,P62750,P09001,P15880,P62753,P39023,P63244,P62910,Q02878 Functions Protein Atlas Protein class protein_atlas_protein_class 133,134,139,140,389,276,275,155,278,293,292,165,167,416,178,177,303,188,306,185,63,186,204,70,198,74,197,195,322,323,220,221,219,218,345,102,242,108,232,231,230,229,386,363,359,360,119,118,248,247,366 539,185,2797,2584,1230,2159,359,360,165,591,303,1833,70,1043,195,1315,595,969,133,3095,118,306,177,108,292,186,167,1113,178,3227,416,639,1922,293,2171,3070,63,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,231,198,1244,247,2264,188,140,248,322,3180,1684,278,3000,2267,1597,2014,1850,155,232,323,220,366,134,2017,3043,3159,221,1694,692,871,1787,2614,3077,2295,2388,2200,2298,2700,2828,1424,1710,204,1433,1887,1212,2561,1152,941,1536,3207,3143,242,2134,2223,386,496,2715,1728,662,1654,1819,716,2784,455,1223,102 0.6361522503407359,1.3231682601538646,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,-0.1940306860173823,1.0241336866990407,-0.3248598804887178,-0.9559681035265681,2.2364769766120918,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.1373892537486945,0.9478531474732188,-1.142327166182432,-0.06480379588709152,1.0620389315076852,-0.8637791771530676,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,-0.15077592925131486,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,-0.23746346936348223,-0.9097905400273109,-1.0954913801193207,1.212138715175788,-0.06480379588709152,0.51638636702171,0.3949453920319386,-0.10770002139860704,-0.546410842239735,-0.9559681035265681,-0.36882191692968064,-0.412958796825298,-0.3248598804887178,-0.36882191692968064,-0.5912394888767456,-0.6814093200124656,0.06279828060143189,-0.06480379588709152,1.2863020037686608,0.06279828060143189,-0.15077592925131486,0.18875209347989597,-0.5017540153159744,0.23036622014532987,0.3540841185619894,0.020446217421404334,-1.1893259001279373,-1.0488191777371687,1.1748381597601374,-0.2810734678085235,-0.3248598804887178,0.8709321917690549,0.7150999985878068,-0.5912394888767456,-0.06480379588709152,0.5564909583357176,-0.022088097488964575,-0.10770002139860704,0.51638636702171,-0.6362392226649662,0.754312439228042,0.18875209347989597,1.7549981936289338 3367 Secretory granule membrane 21 63 3.903375108354858 9.486051000306972e-05 Q9Y2Q5,P07602,P63167,P13473,Q92542,Q9NZJ7,P42785,O00462,O15260,Q5T4S7,P35613,P11717,P10253,P27105,Q709C8,P01889,P11279,P10321,Q13576,Q08431,P46940 Localization GO Cellular component msigdb_gocc 136,17,277,26,159,162,31,40,49,309,305,53,59,62,200,84,90,213,235,233,246 2944,40,1298,49,1738,2847,2426,300,630,786,3254,84,17,59,213,90,53,26,2588,2345,2908,62,1476,1578,2443,305,3067,31,246,2085,1927,908,2365,2369,1243,2960,1245,277,514,1331,233,2524,235,983,1405,309,1947,690,200,2758,2544,159,923,1878,3188,1961,1007,1642,162,2412,2713,136,2647 -0.8179346882917339,3.1081955602316613,0.10496721166567786,2.793240616952005,-0.10770002139860704,-0.7267490661171271,-0.4572697498231123,0.9860724317343753,0.5564909583357176,0.4356160170646649,-1.378937844623164,1.9985415804284918,4.3750256940936305,2.4362503004565204,1.212138715175788,1.8948765913387664,2.664757267155283,3.713721512871941,-0.546410842239735,-0.412958796825298,-0.7722577547913748,2.270032897213297,0.020446217421404334,-0.022088097488964575,-0.4572697498231123,0.9860724317343753,-0.9559681035265681,3.4450326941058216,1.1373892537486945,-0.2810734678085235,-0.1940306860173823,0.3540841185619894,-0.412958796825298,-0.412958796825298,0.14695211780225223,-0.8179346882917339,0.14695211780225223,1.0620389315076852,0.6757140740040977,0.10496721166567786,1.1748381597601374,-0.5017540153159744,1.1748381597601374,0.31303318522898527,0.06279828060143189,0.9860724317343753,-0.1940306860173823,0.51638636702171,1.2863020037686608,-0.6362392226649662,-0.5017540153159744,1.4329258820598159,0.3540841185619894,-0.15077592925131486,-1.142327166182432,-0.1940306860173823,0.31303318522898527,-0.022088097488964575,1.4329258820598159,-0.412958796825298,-0.5912394888767456,1.5414559276361184,-0.546410842239735 3367 Protease 18 87 3.884851987358397 0.0001023922491649 Q9UIQ6,O14773,Q9UPT9,P10619,Q9UPU5,Q01804,Q9HB40,P42574,O75976,Q9NUQ7,Q70CQ2,P42892,Q9H3G5,Q99538,P53634,Q2T9J0,P28072,P42785 Functions Protein Atlas Molecular function protein_atlas_molecular_function 32,2,205,68,244,71,9,260,45,315,280,16,19,20,274,92,272,31 1095,1737,2,1562,1982,1904,45,1032,437,2586,2854,68,790,542,1992,272,1577,2801,2352,1581,260,1917,31,16,2739,2595,907,2448,2006,1587,274,2663,1844,2178,975,365,2090,71,392,2672,3101,2532,92,2604,2461,2821,2382,989,280,2879,2285,1415,1073,1954,1955,1516,311,1877,2973,1276,1632,1880,2479,2208,1431,2480,20,1640,19,1151,531,1809,9,2048,2709,315,2222,944,1157,3209,32,205,244,717,663,2493,2644 0.23036622014532987,-0.10770002139860704,5.884770299255648,-0.022088097488964575,-0.23746346936348223,-0.1940306860173823,3.014617485988229,0.27179356591045745,0.754312439228042,-0.546410842239735,-0.7267490661171271,2.1690444425785262,0.4356160170646649,0.6361522503407359,-0.23746346936348223,1.0620389315076852,-0.022088097488964575,-0.6814093200124656,-0.412958796825298,-0.022088097488964575,1.099790142352336,-0.1940306860173823,3.4450326941058216,4.4588127644301565,-0.6362392226649662,-0.546410842239735,0.3540841185619894,-0.4572697498231123,-0.23746346936348223,-0.022088097488964575,1.0620389315076852,-0.5912394888767456,-0.15077592925131486,-0.3248598804887178,0.31303318522898527,0.8709321917690549,-0.2810734678085235,2.1351656880009666,0.8322262551325478,-0.5912394888767456,-1.0023112020703986,-0.5017540153159744,1.8948765913387664,-0.546410842239735,-0.4572697498231123,-0.6814093200124656,-0.412958796825298,0.31303318522898527,1.0620389315076852,-0.7267490661171271,-0.36882191692968064,0.06279828060143189,0.27179356591045745,-0.1940306860173823,-0.1940306860173823,0.020446217421404334,0.9860724317343753,-0.15077592925131486,-0.8179346882917339,0.14695211780225223,-0.022088097488964575,-0.15077592925131486,-0.4572697498231123,-0.3248598804887178,0.06279828060143189,-0.4572697498231123,3.9186948792031995,-0.022088097488964575,3.9766430116579654,0.23036622014532987,0.6757140740040977,-0.10770002139860704,5.321323717121585,-0.23746346936348223,-0.5912394888767456,0.9860724317343753,-0.3248598804887178,0.3540841185619894,0.23036622014532987,-1.1893259001279373,3.354118052447859,1.2863020037686608,1.1748381597601374,0.51638636702171,0.5564909583357176,-0.4572697498231123,-0.546410842239735 3367 Abnormality of the vasculature of the eye 16 75 3.882835355971801 0.0001032454792504 P02786,P10619,P04066,Q14739,O00462,P04439,P07686,Q13510,P17900,P06865,P07602,P01889,Q6P2Q9,Q8WYQ5,P06280,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 67,68,6,38,40,73,103,104,46,47,17,84,149,87,23,162 666,40,1300,498,1104,2335,1029,1228,1903,1106,3090,2246,84,67,6,73,1378,23,47,17,103,2727,68,1987,2073,164,46,1042,671,844,2349,1752,1994,2860,2733,847,2509,1914,1580,2082,2911,1389,2912,597,2358,3258,547,735,2007,2089,1248,1185,1771,324,2376,104,38,3302,1259,149,1203,3012,87,526,2548,1205,1273,2476,1350,2211,3085,944,162,710,774 0.51638636702171,3.1081955602316613,0.10496721166567786,0.6757140740040977,0.23036622014532987,-0.412958796825298,0.27179356591045745,0.14695211780225223,-0.1940306860173823,0.23036622014532987,-1.0023112020703986,-0.36882191692968064,1.9985415804284918,2.202814512277326,5.477203395245907,2.1011771507196184,0.06279828060143189,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,-0.6362392226649662,2.1690444425785262,-0.23746346936348223,-0.2810734678085235,1.3964785412072227,3.014617485988229,0.27179356591045745,0.51638636702171,0.3949453920319386,-0.412958796825298,-0.10770002139860704,-0.23746346936348223,-0.7267490661171271,-0.6362392226649662,0.3949453920319386,-0.5017540153159744,-0.1940306860173823,-0.022088097488964575,-0.2810734678085235,-0.7722577547913748,0.06279828060143189,-0.7722577547913748,0.5964120554641071,-0.412958796825298,-1.378937844623164,0.6361522503407359,0.4760956266149155,-0.23746346936348223,-0.2810734678085235,0.14695211780225223,0.18875209347989597,-0.10770002139860704,0.9478531474732188,-0.412958796825298,1.719723884747831,3.1701628794451158,-1.6195456688999854,0.14695211780225223,1.469236846394831,0.18875209347989597,-0.8637791771530676,1.9641025522127773,0.6757140740040977,-0.5017540153159744,0.18875209347989597,0.14695211780225223,-0.4572697498231123,0.10496721166567786,-0.3248598804887178,-0.9559681035265681,0.3540841185619894,1.4329258820598159,0.51638636702171,0.4760956266149155 3367 Intrinsic component of plasma membrane 25 72 3.8534612249181386 0.0001164597137985 P30825,Q13641,P05067,Q92542,Q9UIQ6,O60637,P53985,Q9BX67,P35613,P11717,P27105,P02786,Q99805,P04439,Q99996,O15118,Q99808,P01889,P11279,O43657,P19022,P10321,Q8WTV0,Q07954,O14786 Localization GO Cellular component msigdb_gocc 259,141,14,159,32,34,294,313,305,53,62,67,202,73,79,81,225,84,90,95,214,213,110,120,127 1898,2944,839,127,720,1299,81,459,95,1105,34,463,2503,84,67,73,2796,14,788,1309,213,466,90,53,1040,1173,214,2435,592,62,846,259,3242,305,1999,2355,2086,294,511,2916,739,1248,120,1853,798,1855,141,330,3102,2677,1948,750,1348,2617,2544,110,159,1956,202,225,79,1715,313,1007,2049,2128,404,32,2567,2056,833,3354 -0.1940306860173823,-0.8179346882917339,0.3949453920319386,1.5773671103553362,0.4760956266149155,0.10496721166567786,2.032866242545018,0.7150999985878068,1.8600872021750683,0.23036622014532987,3.2931188459257212,0.7150999985878068,-0.5017540153159744,1.9985415804284918,2.202814512277326,2.1011771507196184,-0.6814093200124656,4.815860976496678,0.4356160170646649,0.10496721166567786,1.212138715175788,0.7150999985878068,1.8948765913387664,2.664757267155283,0.27179356591045745,0.18875209347989597,1.212138715175788,-0.4572697498231123,0.5964120554641071,2.270032897213297,0.3949453920319386,1.099790142352336,-1.3312935370263337,0.9860724317343753,-0.23746346936348223,-0.412958796825298,-0.2810734678085235,1.0241336866990407,0.6757140740040977,-0.7722577547913748,0.4760956266149155,0.14695211780225223,1.613148049789865,-0.15077592925131486,0.4356160170646649,-0.15077592925131486,1.5054130123499248,0.9478531474732188,-1.0023112020703986,-0.5912394888767456,-0.1940306860173823,0.4760956266149155,0.10496721166567786,-0.546410842239735,-0.5017540153159744,1.6843250163853651,1.4329258820598159,-0.1940306860173823,1.2863020037686608,1.212138715175788,2.0670777141599412,-0.06480379588709152,0.9860724317343753,0.31303318522898527,-0.23746346936348223,-0.2810734678085235,0.8322262551325478,3.354118052447859,-0.5017540153159744,-0.23746346936348223,0.4356160170646649,-2.6721680762670923 3367 Regulation of expression of slits and robos 50 123 3.7971967276321466 0.0001463416482525 Q04637,P36578,Q07020,O75832,P62841,P63173,P62851,P62424,P61353,P28072,P83731,P50914,P61289,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P40429,Q14118,Q15369,P46778,P25398,P62899,P61313,P62847,P27635,O94813,P84098,Q02543,P61927,P61513,P62241,Q9Y3U8,P62701,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 515,133,134,500,139,140,389,276,275,272,155,293,295,292,165,167,416,178,177,303,188,306,327,331,186,70,198,74,197,195,194,323,220,219,218,345,102,471,108,232,231,230,229,364,363,360,119,118,247,366 1297,2843,2235,1737,2237,1455,500,194,2797,2584,1230,2159,2729,3194,360,2346,165,591,303,504,1833,70,2254,2351,2255,674,1043,195,2075,2860,272,1577,1315,595,969,2512,133,2593,3095,118,306,177,3243,108,292,186,167,1113,178,3227,416,1677,639,1924,2359,293,1238,2519,851,1242,229,910,295,74,275,218,219,1054,2665,3230,345,680,3072,854,230,1594,855,794,795,2521,276,2743,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,155,232,323,220,366,515,2016,134,2372,1333,1059,327,914,1858,804,331,3003,1431,2555,1534,1213,1548,1817,102,2418 0.10496721166567786,-0.7267490661171271,-0.36882191692968064,-0.10770002139860704,-0.36882191692968064,0.020446217421404334,0.6757140740040977,1.2863020037686608,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,-0.6362392226649662,-1.1893259001279373,0.8709321917690549,-0.412958796825298,1.3964785412072227,0.5964120554641071,0.9860724317343753,0.6757140740040977,-0.15077592925131486,2.1351656880009666,-0.36882191692968064,-0.412958796825298,-0.36882191692968064,0.51638636702171,0.27179356591045745,1.2863020037686608,-0.2810734678085235,-0.7267490661171271,1.0620389315076852,-0.022088097488964575,0.10496721166567786,0.5964120554641071,0.31303318522898527,-0.5017540153159744,1.5414559276361184,-0.546410842239735,-1.0023112020703986,1.613148049789865,0.9860724317343753,1.3598932144259221,-1.3312935370263337,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,-0.06480379588709152,0.5564909583357176,-0.1940306860173823,-0.412958796825298,1.0241336866990407,0.14695211780225223,-0.5017540153159744,0.3949453920319386,0.14695211780225223,1.1748381597601374,0.3540841185619894,1.0241336866990407,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,-0.5912394888767456,-1.2838097038521317,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,-0.5017540153159744,1.0620389315076852,-0.6362392226649662,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,0.6757140740040977,-0.23746346936348223,1.5414559276361184,-0.412958796825298,0.10496721166567786,0.27179356591045745,0.9478531474732188,0.3540841185619894,-0.15077592925131486,0.4356160170646649,0.9478531474732188,-0.8637791771530676,0.06279828060143189,-0.5017540153159744,0.020446217421404334,0.18875209347989597,0.020446217421404334,-0.10770002139860704,1.7549981936289338,-0.412958796825298 3367 Exopeptidase activity 9 31 3.786196652751735 0.0001529706322749 Q9UIQ6,O14773,P02786,P10619,Q9HB40,O75976,Q9H3G5,Q96DE0,P42785 Functions GO Molecular function msigdb_gomf 32,2,67,68,9,45,19,28,31 2,1904,45,67,2854,68,790,2801,2352,1999,31,907,274,1844,3098,392,2285,1869,77,2929,28,1880,3188,19,1151,9,2048,2709,2222,944,32 5.884770299255648,-0.1940306860173823,3.014617485988229,2.202814512277326,-0.7267490661171271,2.1690444425785262,0.4356160170646649,-0.6814093200124656,-0.412958796825298,-0.23746346936348223,3.4450326941058216,0.3540841185619894,1.0620389315076852,-0.15077592925131486,-1.0023112020703986,0.8322262551325478,-0.36882191692968064,-0.15077592925131486,2.0670777141599412,-0.7722577547913748,3.535260987655072,-0.15077592925131486,-1.142327166182432,3.9766430116579654,0.23036622014532987,5.321323717121585,-0.23746346936348223,-0.5912394888767456,-0.3248598804887178,0.3540841185619894,3.354118052447859 3367 Mental deterioration 22 100 3.777021345703152 0.0001587151337296 O75503,P05067,P07602,P61916,Q14108,Q9NZJ7,O96008,P50897,P16278,P17900,P06865,P26358,P54802,O75165,Q709C8,Q9NPL8,O15118,P42858,P07686,Q13510,Q96F07,Q13501 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,14,17,25,27,162,271,35,164,46,47,176,54,300,200,80,81,100,103,104,111,234 1451,81,1301,1901,2846,2722,300,1903,3,2792,668,271,728,841,3149,465,14,47,17,103,2853,1570,2072,2341,1748,413,164,439,46,1042,3240,2349,1752,2506,176,3333,847,1997,1319,3214,3177,1048,100,1839,1918,2913,35,1482,1325,54,1589,2262,25,2741,796,3130,2091,515,2813,2182,2744,1772,1687,1490,234,104,27,1604,3158,2682,868,2281,1613,919,200,2610,876,485,1205,2202,111,1074,816,1075,2480,1714,2887,351,80,885,575,3114,162,1896,1442,2894,950,2717,1295,2897 0.020446217421404334,2.032866242545018,0.10496721166567786,-0.1940306860173823,-0.7267490661171271,-0.6362392226649662,0.9860724317343753,-0.1940306860173823,5.682423722639393,-0.6814093200124656,0.51638636702171,1.0620389315076852,0.4760956266149155,0.3949453920319386,-1.0954913801193207,0.7150999985878068,4.815860976496678,2.9518057266228475,4.3750256940936305,1.719723884747831,-0.7267490661171271,-0.022088097488964575,-0.2810734678085235,-0.412958796825298,-0.10770002139860704,0.7933537558921767,1.3964785412072227,0.754312439228042,3.014617485988229,0.27179356591045745,-1.3312935370263337,-0.412958796825298,-0.10770002139860704,-0.5017540153159744,1.3598932144259221,-2.1124650811200967,0.3949453920319386,-0.23746346936348223,0.10496721166567786,-1.2364869532593843,-1.142327166182432,0.27179356591045745,1.7549981936289338,-0.15077592925131486,-0.1940306860173823,-0.7722577547913748,3.2625005214835268,0.020446217421404334,0.10496721166567786,2.664757267155283,-0.022088097488964575,-0.36882191692968064,3.772633277255873,-0.6362392226649662,0.4356160170646649,-1.0488191777371687,-0.2810734678085235,0.6757140740040977,-0.6814093200124656,-0.3248598804887178,-0.6362392226649662,-0.10770002139860704,-0.06480379588709152,0.020446217421404334,1.1748381597601374,1.719723884747831,3.6248188309031892,-0.022088097488964575,-1.0954913801193207,-0.5912394888767456,0.3949453920319386,-0.36882191692968064,-0.022088097488964575,0.3540841185619894,1.2863020037686608,-0.546410842239735,0.3949453920319386,0.7150999985878068,0.18875209347989597,-0.3248598804887178,1.6843250163853651,0.27179356591045745,0.4356160170646649,0.27179356591045745,-0.4572697498231123,-0.06480379588709152,-0.7267490661171271,0.909473770504105,2.0670777141599412,0.3949453920319386,0.6361522503407359,-1.0023112020703986,1.4329258820598159,-0.15077592925131486,0.06279828060143189,-0.7267490661171271,0.3540841185619894,-0.5912394888767456,0.14695211780225223,-0.7267490661171271 3367 Vacuole 44 209 3.748801262540212 0.0001776818123662 O14773,O75503,Q9BTY2,Q9Y2Q5,P04066,Q9UM22,Q5BJF2,P15586,Q8NHP8,P42892,P07602,O00584,Q99538,P06280,P61916,P13473,Q14108,Q92542,Q9NZJ7,P42785,Q9UIQ6,P50897,O00462,P11117,O00754,P17900,P06865,O15260,Q8IV08,P54802,P10253,Q8NCC3,P27105,P10619,Q92820,O15118,P11279,P42858,P07686,Q13510,Q8WTV0,P42345,Q99536,Q07954 Localization GO Cellular component msigdb_gocc 2,3,4,136,6,8,10,13,15,16,17,18,20,23,25,26,27,159,162,31,32,35,40,41,44,46,47,49,51,54,59,60,62,68,77,81,90,100,103,104,110,107,124,120 408,40,839,18,44,183,2,1098,81,49,781,1103,3062,1899,1301,959,1028,2242,2426,300,1981,3,501,786,3254,1308,1907,2070,841,6,670,23,47,2986,2586,1170,17,103,2158,3312,1464,2071,2340,412,2248,59,68,41,2587,1571,90,26,413,13,164,1992,46,3091,592,844,2348,2250,1993,62,304,2800,1670,2802,507,2660,2166,3214,1389,2168,3177,3067,2355,107,31,100,16,2739,2956,596,546,2447,735,35,2997,3305,1927,908,307,1114,274,2864,1929,54,2262,2087,972,2809,1117,1243,2370,737,25,1055,1595,1483,1246,1485,796,1767,1768,1183,2813,2268,1331,120,1057,1771,644,2868,3132,234,104,3157,1122,27,328,370,330,2188,420,476,1337,10,690,51,752,421,2196,60,2758,1873,15,617,1204,110,2760,993,159,77,923,2476,1878,2205,564,487,1425,2765,1074,816,2555,124,20,350,3164,3188,1715,4,1286,1961,569,3298,1007,1080,3141,2403,3142,2214,1720,2937,2219,2711,1967,1364,162,2412,2226,1441,532,2318,354,32,3116,8,890,3170,833,579,136,2324,3335,1295,287,2646,1224 0.7933537558921767,3.1081955602316613,0.3949453920319386,4.120355977593298,3.014617485988229,1.3231682601538646,5.884770299255648,0.23036622014532987,2.032866242545018,2.793240616952005,0.4356160170646649,0.23036622014532987,-0.9559681035265681,-0.1940306860173823,0.10496721166567786,0.31303318522898527,0.27179356591045745,-0.36882191692968064,-0.4572697498231123,0.9860724317343753,-0.23746346936348223,5.682423722639393,0.6757140740040977,0.4356160170646649,-1.378937844623164,0.10496721166567786,-0.1940306860173823,-0.2810734678085235,0.3949453920319386,5.477203395245907,0.51638636702171,3.860476447122193,2.9518057266228475,-0.8637791771530676,-0.546410842239735,0.18875209347989597,4.3750256940936305,1.719723884747831,-0.3248598804887178,-1.7657985305992057,0.020446217421404334,-0.2810734678085235,-0.412958796825298,0.7933537558921767,-0.36882191692968064,2.4362503004565204,2.1690444425785262,3.077087184000687,-0.546410842239735,-0.022088097488964575,1.8948765913387664,3.713721512871941,0.7933537558921767,4.896921049154351,1.3964785412072227,-0.23746346936348223,3.014617485988229,-1.0023112020703986,0.5964120554641071,0.3949453920319386,-0.412958796825298,-0.36882191692968064,-0.23746346936348223,2.270032897213297,0.9860724317343753,-0.6814093200124656,-0.06480379588709152,-0.6814093200124656,0.6757140740040977,-0.5912394888767456,-0.3248598804887178,-1.2364869532593843,0.06279828060143189,-0.3248598804887178,-1.142327166182432,-0.9559681035265681,-0.412958796825298,1.6843250163853651,3.4450326941058216,1.7549981936289338,4.4588127644301565,-0.6362392226649662,-0.8179346882917339,0.5964120554641071,0.6361522503407359,-0.4572697498231123,0.4760956266149155,3.2625005214835268,-0.8637791771530676,-1.6681404132370228,-0.1940306860173823,0.3540841185619894,0.9860724317343753,0.23036622014532987,1.0620389315076852,-0.7267490661171271,-0.1940306860173823,2.664757267155283,-0.36882191692968064,-0.2810734678085235,0.31303318522898527,-0.6814093200124656,0.23036622014532987,0.14695211780225223,-0.412958796825298,0.4760956266149155,3.772633277255873,0.27179356591045745,-0.022088097488964575,0.020446217421404334,0.14695211780225223,0.020446217421404334,0.4356160170646649,-0.10770002139860704,-0.10770002139860704,0.18875209347989597,-0.6814093200124656,-0.36882191692968064,0.10496721166567786,1.613148049789865,0.27179356591045745,-0.10770002139860704,0.5564909583357176,-0.7267490661171271,-1.0488191777371687,1.1748381597601374,1.719723884747831,-1.0954913801193207,0.23036622014532987,3.6248188309031892,0.9478531474732188,0.8709321917690549,0.9478531474732188,-0.3248598804887178,0.7933537558921767,0.7150999985878068,0.10496721166567786,5.216435956950591,0.51638636702171,2.7291839700941773,0.4760956266149155,0.7933537558921767,-0.3248598804887178,2.3368292667835435,-0.6362392226649662,-0.15077592925131486,4.815860976496678,0.5964120554641071,0.18875209347989597,1.6843250163853651,-0.6362392226649662,0.31303318522898527,1.4329258820598159,2.0670777141599412,0.3540841185619894,-0.4572697498231123,-0.15077592925131486,-0.3248598804887178,0.6361522503407359,0.7150999985878068,0.06279828060143189,-0.6362392226649662,0.27179356591045745,0.4356160170646649,-0.5017540153159744,1.613148049789865,3.9186948792031995,0.909473770504105,-1.0954913801193207,-1.142327166182432,-0.06480379588709152,5.6569309364282425,0.14695211780225223,-0.1940306860173823,0.6361522503407359,-1.5711078846200432,0.31303318522898527,0.27179356591045745,-1.0488191777371687,-0.412958796825298,-1.0488191777371687,-0.3248598804887178,-0.06480379588709152,-0.7722577547913748,-0.3248598804887178,-0.5912394888767456,-0.1940306860173823,0.10496721166567786,1.4329258820598159,-0.412958796825298,-0.3248598804887178,0.06279828060143189,0.6757140740040977,-0.36882191692968064,0.909473770504105,3.354118052447859,-1.0023112020703986,5.347423495313898,0.3949453920319386,-1.0954913801193207,0.4356160170646649,0.6361522503407359,1.5414559276361184,-0.36882191692968064,-2.1625993189318375,0.14695211780225223,1.0620389315076852,-0.546410842239735,0.18875209347989597 3367 Hydrolase activity hydrolyzing o glycosyl compounds 10 23 3.726116411270113 0.000194452625317 Q9BTY2,P04066,P07686,O00462,O00754,P17900,P06865,P54802,P06280,P10253 Functions GO Molecular function msigdb_gomf 4,6,103,40,44,46,47,54,23,59 40,44,783,2946,841,6,23,47,103,59,164,46,440,54,2091,1494,2021,1944,2692,4,2130,2838,2490 3.1081955602316613,3.014617485988229,0.4356160170646649,-0.8179346882917339,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,1.719723884747831,2.4362503004565204,1.3964785412072227,3.014617485988229,0.754312439228042,2.664757267155283,-0.2810734678085235,0.020446217421404334,-0.23746346936348223,-0.1940306860173823,-0.5912394888767456,5.6569309364282425,-0.2810734678085235,-0.6814093200124656,-0.4572697498231123 3367 Sterol metabolic process 9 40 3.7123189936262495 0.0002053689243881 Q15392,Q9UBM7,Q14739,Q15125,Q8WTV0,P05067,O15118,P61916,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,38,7,110,14,81,25,30 81,2501,2070,841,14,1572,2731,2991,1832,1579,361,30,2168,3069,215,2003,1114,1762,2807,25,1686,3339,1185,645,1252,1857,38,370,2922,7,3075,0,2024,446,157,110,2887,1,831,2713 2.032866242545018,-0.5017540153159744,-0.2810734678085235,0.3949453920319386,4.815860976496678,-0.022088097488964575,-0.6362392226649662,-0.8637791771530676,-0.15077592925131486,-0.022088097488964575,0.8709321917690549,3.4751842548839553,-0.3248598804887178,-0.9559681035265681,1.212138715175788,-0.23746346936348223,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,3.772633277255873,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,-0.15077592925131486,3.1701628794451158,0.8709321917690549,-0.7722577547913748,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,1.6843250163853651,-0.7267490661171271,6.354521266861696,0.4356160170646649,-0.5912394888767456 3367 Receptor 15 35 3.709543113796772 0.0002076335991068 Q5KU26,P02786,Q99720,Q14739,P55899,P30825,Q8WTV0,O15118,P35613,P11717,Q9Y2I1,Q07954,P11279,Q14108,O14786 Functions Protein Atlas Molecular function protein_atlas_molecular_function 66,67,37,38,43,259,110,81,305,53,126,120,90,27,127 2944,127,720,81,2899,67,1309,1826,1665,2159,1466,90,53,542,592,673,259,305,43,120,1855,27,327,38,2677,66,110,697,3286,37,2314,126,1221,2645,775 -0.8179346882917339,1.5773671103553362,0.4760956266149155,2.032866242545018,-0.7722577547913748,2.202814512277326,0.10496721166567786,-0.15077592925131486,-0.06480379588709152,-0.3248598804887178,0.020446217421404334,1.8948765913387664,2.664757267155283,0.6361522503407359,0.5964120554641071,0.51638636702171,1.099790142352336,0.9860724317343753,3.0458947300580568,1.613148049789865,-0.15077592925131486,3.6248188309031892,0.9478531474732188,3.1701628794451158,-0.5912394888767456,2.2364769766120918,1.6843250163853651,0.51638636702171,-1.4747054833332776,3.201023198065498,-0.36882191692968064,1.613148049789865,0.18875209347989597,-0.546410842239735,0.4760956266149155 3367 Steroid metabolic process 14 71 3.689393635744696 0.000224789184102 Q15392,Q9UBM7,P48449,Q14739,Q15125,Q13510,Q8WTV0,P28288,P05067,O15118,Q99538,Q16850,P61916,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,215,38,7,104,110,258,14,81,20,157,25,30 1821,1298,81,2501,668,2070,841,2796,14,3174,1572,2731,1990,2991,1110,2993,1832,2799,258,290,1579,361,30,1389,2168,3069,215,2003,1325,2363,1114,1762,2807,25,1686,3339,1185,1186,645,104,1252,1857,38,370,2922,7,3075,0,687,607,2024,446,157,1193,690,1269,110,2763,758,20,1714,2887,1639,571,1962,1358,1,831,1545,2713,2894 -0.15077592925131486,0.10496721166567786,2.032866242545018,-0.5017540153159744,0.51638636702171,-0.2810734678085235,0.3949453920319386,-0.6814093200124656,4.815860976496678,-1.142327166182432,-0.022088097488964575,-0.6362392226649662,-0.23746346936348223,-0.8637791771530676,0.23036622014532987,-0.8637791771530676,-0.15077592925131486,-0.6814093200124656,1.099790142352336,1.0241336866990407,-0.022088097488964575,0.8709321917690549,3.4751842548839553,0.06279828060143189,-0.3248598804887178,-0.9559681035265681,1.212138715175788,-0.23746346936348223,0.10496721166567786,-0.412958796825298,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,3.772633277255873,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,0.18875209347989597,0.5564909583357176,1.719723884747831,0.14695211780225223,-0.15077592925131486,3.1701628794451158,0.8709321917690549,-0.7722577547913748,5.347423495313898,-0.9559681035265681,9.266342596549883,0.51638636702171,0.5964120554641071,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.18875209347989597,0.51638636702171,0.14695211780225223,1.6843250163853651,-0.6362392226649662,0.4760956266149155,3.9186948792031995,-0.06480379588709152,-0.7267490661171271,-0.022088097488964575,0.6361522503407359,-0.1940306860173823,0.10496721166567786,6.354521266861696,0.4356160170646649,0.020446217421404334,-0.5912394888767456,-0.7267490661171271 3367 Glycosidase 9 19 3.656742715113606 0.0002554405383696 Q9BTY2,P04066,P07686,O00462,O00754,P06865,P54802,P06280,P10253 Functions Protein Atlas Molecular function protein_atlas_molecular_function 4,6,103,40,44,47,54,23,59 40,44,2144,783,2946,841,6,23,47,103,59,164,440,54,1933,1494,2021,1944,4 3.1081955602316613,3.014617485988229,-0.3248598804887178,0.4356160170646649,-0.8179346882917339,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,1.719723884747831,2.4362503004565204,1.3964785412072227,0.754312439228042,2.664757267155283,-0.1940306860173823,0.020446217421404334,-0.23746346936348223,-0.1940306860173823,5.6569309364282425 3367 Abnormality of the spleen 21 133 3.646386155487406 0.0002659542232825 Q15392,P04066,P15586,P07602,P61916,Q14108,Q9NZJ7,Q658P3,Q14739,P16278,O00754,Q15904,P54802,P10253,P10619,O15118,P01889,Q86V48,P07686,Q13510,P14174 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,6,13,17,25,27,162,36,38,164,44,48,54,59,68,81,84,98,103,104,116 408,357,44,183,1974,81,3211,2651,1228,2652,724,3173,727,1743,2903,1377,1825,84,3148,841,6,1463,2582,1378,2157,3193,17,103,2159,59,68,466,1231,2342,2990,1572,790,116,13,164,1174,2907,2348,1752,1575,2949,2800,2860,258,2352,1318,1999,2259,2000,2168,636,1582,2513,3315,906,1320,597,2358,735,1482,2363,307,2007,2175,54,1590,2008,1240,25,3229,1685,1185,2091,2268,2815,1772,1600,1119,2376,104,1058,1494,27,38,0,1860,2459,420,48,476,2104,36,2822,377,3047,98,1791,1203,2471,1625,2548,1273,2622,2930,2476,1523,1353,1633,816,2207,1530,530,1007,1361,2631,2134,944,162,2567,3116,948,2490,2570,3192,2942,2232,2418,2646 0.7933537558921767,0.8709321917690549,3.014617485988229,1.3231682601538646,-0.23746346936348223,2.032866242545018,-1.2364869532593843,-0.5912394888767456,0.14695211780225223,-0.5912394888767456,0.4760956266149155,-1.142327166182432,0.4760956266149155,-0.10770002139860704,-0.7722577547913748,0.06279828060143189,-0.15077592925131486,1.9985415804284918,-1.0954913801193207,0.3949453920319386,5.477203395245907,0.020446217421404334,-0.546410842239735,0.06279828060143189,-0.3248598804887178,-1.1893259001279373,4.3750256940936305,1.719723884747831,-0.3248598804887178,2.4362503004565204,2.1690444425785262,0.7150999985878068,0.14695211780225223,-0.412958796825298,-0.8637791771530676,-0.022088097488964575,0.4356160170646649,1.613148049789865,4.896921049154351,1.3964785412072227,0.18875209347989597,-0.7722577547913748,-0.412958796825298,-0.10770002139860704,-0.022088097488964575,-0.8179346882917339,-0.6814093200124656,-0.7267490661171271,1.099790142352336,-0.412958796825298,0.10496721166567786,-0.23746346936348223,-0.36882191692968064,-0.23746346936348223,-0.3248598804887178,0.5564909583357176,-0.022088097488964575,-0.5017540153159744,-1.7657985305992057,0.3540841185619894,0.10496721166567786,0.5964120554641071,-0.412958796825298,0.4760956266149155,0.020446217421404334,-0.412958796825298,0.9860724317343753,-0.23746346936348223,-0.3248598804887178,2.664757267155283,-0.022088097488964575,-0.23746346936348223,0.14695211780225223,3.772633277255873,-1.2838097038521317,-0.06480379588709152,0.18875209347989597,-0.2810734678085235,-0.36882191692968064,-0.6814093200124656,-0.10770002139860704,-0.022088097488964575,0.23036622014532987,-0.412958796825298,1.719723884747831,0.27179356591045745,0.020446217421404334,3.6248188309031892,3.1701628794451158,9.266342596549883,-0.15077592925131486,-0.4572697498231123,0.7933537558921767,2.888645998928826,0.7150999985878068,-0.2810734678085235,3.201023198065498,-0.6814093200124656,0.8709321917690549,-0.9097905400273109,1.790149299150869,-0.10770002139860704,0.18875209347989597,-0.4572697498231123,-0.022088097488964575,-0.5017540153159744,0.14695211780225223,-0.546410842239735,-0.7722577547913748,-0.4572697498231123,0.020446217421404334,0.10496721166567786,-0.022088097488964575,0.4356160170646649,-0.3248598804887178,0.020446217421404334,0.6757140740040977,0.31303318522898527,0.10496721166567786,-0.546410842239735,-0.2810734678085235,0.3540841185619894,1.4329258820598159,-0.5017540153159744,-1.0023112020703986,0.3540841185619894,-0.4572697498231123,-0.5017540153159744,-1.142327166182432,-0.7722577547913748,-0.3248598804887178,-0.412958796825298,-0.546410842239735 3367 Vesicle lumen 17 124 3.643834374512087 0.0002686063036465 Q9BTY2,P10619,P04066,P07686,P31949,Q08380,O00754,P15586,P17900,P05067,Q92820,O00584,P67870,Q99536,P06280,P61916,P14174 Localization GO Cellular component msigdb_gocc 4,68,6,103,42,11,44,13,46,14,77,18,148,124,23,25,116 2843,2235,1737,839,2497,18,44,1096,1455,1301,1302,3278,1565,2070,1825,6,1463,3149,14,23,1169,2157,2986,1170,103,1664,2158,2071,3174,1038,2505,68,2587,1571,2344,1468,3328,1988,1312,116,1829,2798,413,13,164,1041,46,2346,1668,3280,504,844,1383,2351,2075,1670,2802,507,42,440,2512,1836,596,2447,2997,1238,1114,274,1929,2262,2370,25,148,1246,1329,1485,1768,2268,11,2670,1187,1333,3132,1402,800,1688,328,2528,1858,2025,1506,263,610,810,1510,1870,2926,2196,3356,1624,77,1272,2205,3014,2301,816,1431,1881,2555,124,2932,4,3142,2313,2408,2632,1364,3024,1366,1817,1367,579,770,581 -0.7267490661171271,-0.36882191692968064,-0.10770002139860704,0.3949453920319386,-0.5017540153159744,4.120355977593298,3.014617485988229,0.23036622014532987,0.020446217421404334,0.10496721166567786,0.10496721166567786,-1.4747054833332776,-0.022088097488964575,-0.2810734678085235,-0.15077592925131486,5.477203395245907,0.020446217421404334,-1.0954913801193207,4.815860976496678,3.860476447122193,0.18875209347989597,-0.3248598804887178,-0.8637791771530676,0.18875209347989597,1.719723884747831,-0.06480379588709152,-0.3248598804887178,-0.2810734678085235,-1.142327166182432,0.27179356591045745,-0.5017540153159744,2.1690444425785262,-0.546410842239735,-0.022088097488964575,-0.412958796825298,0.020446217421404334,-2.012651824371249,-0.23746346936348223,0.10496721166567786,1.613148049789865,-0.15077592925131486,-0.6814093200124656,0.7933537558921767,4.896921049154351,1.3964785412072227,0.27179356591045745,3.014617485988229,-0.412958796825298,-0.06480379588709152,-1.4747054833332776,0.6757140740040977,0.3949453920319386,0.06279828060143189,-0.412958796825298,-0.2810734678085235,-0.06480379588709152,-0.6814093200124656,0.6757140740040977,3.0458947300580568,0.754312439228042,-0.5017540153159744,-0.15077592925131486,0.5964120554641071,-0.4572697498231123,-0.8637791771530676,0.14695211780225223,0.23036622014532987,1.0620389315076852,-0.1940306860173823,-0.36882191692968064,-0.412958796825298,3.772633277255873,1.469236846394831,0.14695211780225223,0.10496721166567786,0.020446217421404334,-0.10770002139860704,-0.36882191692968064,5.137248975932357,-0.5912394888767456,0.18875209347989597,0.10496721166567786,-1.0488191777371687,0.06279828060143189,0.4356160170646649,-0.06480379588709152,0.9478531474732188,-0.5017540153159744,-0.15077592925131486,-0.23746346936348223,0.020446217421404334,1.099790142352336,0.5964120554641071,0.4356160170646649,0.020446217421404334,-0.15077592925131486,-0.7722577547913748,-0.3248598804887178,-2.77585155562055,-0.022088097488964575,2.0670777141599412,0.14695211780225223,-0.3248598804887178,-0.8637791771530676,-0.36882191692968064,0.4356160170646649,0.06279828060143189,-0.15077592925131486,-0.5017540153159744,1.613148049789865,-0.7722577547913748,5.6569309364282425,-1.0488191777371687,-0.36882191692968064,-0.412958796825298,-0.546410842239735,0.10496721166567786,-0.8637791771530676,0.10496721166567786,-0.10770002139860704,0.10496721166567786,0.6361522503407359,0.4760956266149155,0.6361522503407359 3367 Vacuolar membrane 22 116 3.584816349029689 0.0003373154797063 O75503,Q9Y2Q5,P42892,P07602,P13473,Q14108,Q92542,Q9NZJ7,P42785,Q9UIQ6,O00462,P11117,O15260,Q8IV08,P10253,P27105,P10619,O15118,P11279,Q8WTV0,P42345,Q07954 Localization GO Cellular component msigdb_gocc 3,136,16,17,26,27,159,162,31,32,40,41,49,51,59,62,68,81,90,110,107,120 408,40,183,81,49,781,1103,1899,959,1028,2426,300,3,501,786,3254,1308,841,670,2986,17,3312,1464,2071,2340,412,59,68,41,2587,90,26,592,2348,2250,1993,62,2660,2166,3214,3177,3067,2355,107,31,16,2956,1927,908,307,2864,2087,972,2809,1243,737,1055,1595,1483,796,2813,1331,120,1057,1771,1122,27,370,330,476,690,51,752,421,2758,1873,110,2760,993,159,923,2476,1878,564,487,1425,2765,1074,816,3164,3188,1715,1961,569,3298,1007,3141,2403,2214,1720,2219,1967,162,2412,2226,532,354,32,890,3170,833,136,2324,3335,1295,2646 0.7933537558921767,3.1081955602316613,1.3231682601538646,2.032866242545018,2.793240616952005,0.4356160170646649,0.23036622014532987,-0.1940306860173823,0.31303318522898527,0.27179356591045745,-0.4572697498231123,0.9860724317343753,5.682423722639393,0.6757140740040977,0.4356160170646649,-1.378937844623164,0.10496721166567786,0.3949453920319386,0.51638636702171,-0.8637791771530676,4.3750256940936305,-1.7657985305992057,0.020446217421404334,-0.2810734678085235,-0.412958796825298,0.7933537558921767,2.4362503004565204,2.1690444425785262,3.077087184000687,-0.546410842239735,1.8948765913387664,3.713721512871941,0.5964120554641071,-0.412958796825298,-0.36882191692968064,-0.23746346936348223,2.270032897213297,-0.5912394888767456,-0.3248598804887178,-1.2364869532593843,-1.142327166182432,-0.9559681035265681,-0.412958796825298,1.6843250163853651,3.4450326941058216,4.4588127644301565,-0.8179346882917339,-0.1940306860173823,0.3540841185619894,0.9860724317343753,-0.7267490661171271,-0.2810734678085235,0.31303318522898527,-0.6814093200124656,0.14695211780225223,0.4760956266149155,0.27179356591045745,-0.022088097488964575,0.020446217421404334,0.4356160170646649,-0.6814093200124656,0.10496721166567786,1.613148049789865,0.27179356591045745,-0.10770002139860704,0.23036622014532987,3.6248188309031892,0.8709321917690549,0.9478531474732188,0.7150999985878068,0.51638636702171,2.7291839700941773,0.4760956266149155,0.7933537558921767,-0.6362392226649662,-0.15077592925131486,1.6843250163853651,-0.6362392226649662,0.31303318522898527,1.4329258820598159,0.3540841185619894,-0.4572697498231123,-0.15077592925131486,0.6361522503407359,0.7150999985878068,0.06279828060143189,-0.6362392226649662,0.27179356591045745,0.4356160170646649,-1.0954913801193207,-1.142327166182432,-0.06480379588709152,-0.1940306860173823,0.6361522503407359,-1.5711078846200432,0.31303318522898527,-1.0488191777371687,-0.412958796825298,-0.3248598804887178,-0.06480379588709152,-0.3248598804887178,-0.1940306860173823,1.4329258820598159,-0.412958796825298,-0.3248598804887178,0.6757140740040977,0.909473770504105,3.354118052447859,0.3949453920319386,-1.0954913801193207,0.4356160170646649,1.5414559276361184,-0.36882191692968064,-2.1625993189318375,0.14695211780225223,-0.546410842239735 3367 Lytic vacuole organization 9 25 3.581486552596473 0.0003416447257671 O14773,P50897,O75503,P07686,P11117,P10253,P42345,P54802,Q14108 Processes and pathways GO Biological process msigdb_gobp 2,35,3,103,41,59,107,54,27 408,2,3,1744,841,103,59,41,107,35,908,54,1243,121,27,690,3104,421,2476,1074,2830,572,2219,2226,2981 0.7933537558921767,5.884770299255648,5.682423722639393,-0.10770002139860704,0.3949453920319386,1.719723884747831,2.4362503004565204,3.077087184000687,1.6843250163853651,3.2625005214835268,0.3540841185619894,2.664757267155283,0.14695211780225223,1.613148049789865,3.6248188309031892,0.51638636702171,-1.0023112020703986,0.7933537558921767,-0.4572697498231123,0.27179356591045745,-0.6814093200124656,0.6361522503407359,-0.3248598804887178,-0.3248598804887178,-0.8179346882917339 3367 Neutrophil degranulation 39 173 3.571813805932675 0.0003545174278793 Q7L576,Q9BTY2,Q9Y2Q5,P04066,P15586,P07602,O00584,P67870,P06280,P61916,P13473,Q92542,P63167,Q9NZJ7,P53634,P42785,O00462,P16278,P31949,O00754,P17900,O15260,Q5T4S7,P11717,O75165,P10253,P27105,P10619,P04439,Q92820,P01889,P11279,P10321,P07686,Q13510,Q13576,Q99536,P14174,P46940 Processes and pathways Reactome Pathways msigdb_reactome 263,4,136,6,13,17,18,148,23,25,26,159,277,162,274,31,40,164,42,44,46,49,309,53,300,59,62,68,73,77,84,90,213,103,104,235,124,116,246 2843,2235,2944,40,1737,839,2497,18,44,1096,1298,49,1455,1301,1738,2426,300,3278,786,1565,3254,2070,1825,84,6,1463,3149,73,23,1169,2157,2986,2586,1170,17,103,1664,2158,2071,3174,1038,2854,2505,1466,59,213,68,2587,1571,90,53,2344,3328,1988,26,1312,2160,116,1829,2798,413,13,2588,164,1041,46,2345,2346,1668,3280,504,844,1383,2351,62,2075,1670,2802,1476,507,42,2443,440,2512,2738,1836,3067,31,246,596,2447,2997,1927,908,1238,1114,2365,274,1929,2262,2369,1243,2370,2960,25,1245,277,148,1246,1329,1485,514,1768,2268,1331,2670,1187,1333,3132,2966,1402,104,235,800,1688,983,328,2528,1858,2025,309,1947,690,263,610,810,1510,1870,2196,2758,2544,1624,159,77,1272,923,1878,2205,3014,2301,1431,1881,2555,124,3188,2932,4,1961,1007,3142,1642,2313,1364,162,2412,3024,1817,1367,579,136,770,581,2647 -0.7267490661171271,-0.36882191692968064,-0.8179346882917339,3.1081955602316613,-0.10770002139860704,0.3949453920319386,-0.5017540153159744,4.120355977593298,3.014617485988229,0.23036622014532987,0.10496721166567786,2.793240616952005,0.020446217421404334,0.10496721166567786,-0.10770002139860704,-0.4572697498231123,0.9860724317343753,-1.4747054833332776,0.4356160170646649,-0.022088097488964575,-1.378937844623164,-0.2810734678085235,-0.15077592925131486,1.9985415804284918,5.477203395245907,0.020446217421404334,-1.0954913801193207,2.1011771507196184,3.860476447122193,0.18875209347989597,-0.3248598804887178,-0.8637791771530676,-0.546410842239735,0.18875209347989597,4.3750256940936305,1.719723884747831,-0.06480379588709152,-0.3248598804887178,-0.2810734678085235,-1.142327166182432,0.27179356591045745,-0.7267490661171271,-0.5017540153159744,0.020446217421404334,2.4362503004565204,1.212138715175788,2.1690444425785262,-0.546410842239735,-0.022088097488964575,1.8948765913387664,2.664757267155283,-0.412958796825298,-2.012651824371249,-0.23746346936348223,3.713721512871941,0.10496721166567786,-0.3248598804887178,1.613148049789865,-0.15077592925131486,-0.6814093200124656,0.7933537558921767,4.896921049154351,-0.546410842239735,1.3964785412072227,0.27179356591045745,3.014617485988229,-0.412958796825298,-0.412958796825298,-0.06480379588709152,-1.4747054833332776,0.6757140740040977,0.3949453920319386,0.06279828060143189,-0.412958796825298,2.270032897213297,-0.2810734678085235,-0.06480379588709152,-0.6814093200124656,0.020446217421404334,0.6757140740040977,3.0458947300580568,-0.4572697498231123,0.754312439228042,-0.5017540153159744,-0.6362392226649662,-0.15077592925131486,-0.9559681035265681,3.4450326941058216,1.1373892537486945,0.5964120554641071,-0.4572697498231123,-0.8637791771530676,-0.1940306860173823,0.3540841185619894,0.14695211780225223,0.23036622014532987,-0.412958796825298,1.0620389315076852,-0.1940306860173823,-0.36882191692968064,-0.412958796825298,0.14695211780225223,-0.412958796825298,-0.8179346882917339,3.772633277255873,0.14695211780225223,1.0620389315076852,1.469236846394831,0.14695211780225223,0.10496721166567786,0.020446217421404334,0.6757140740040977,-0.10770002139860704,-0.36882191692968064,0.10496721166567786,-0.5912394888767456,0.18875209347989597,0.10496721166567786,-1.0488191777371687,-0.8179346882917339,0.06279828060143189,1.719723884747831,1.1748381597601374,0.4356160170646649,-0.06480379588709152,0.31303318522898527,0.9478531474732188,-0.5017540153159744,-0.15077592925131486,-0.23746346936348223,0.9860724317343753,-0.1940306860173823,0.51638636702171,1.099790142352336,0.5964120554641071,0.4356160170646649,0.020446217421404334,-0.15077592925131486,-0.3248598804887178,-0.6362392226649662,-0.5017540153159744,-0.022088097488964575,1.4329258820598159,2.0670777141599412,0.14695211780225223,0.3540841185619894,-0.15077592925131486,-0.3248598804887178,-0.8637791771530676,-0.36882191692968064,0.06279828060143189,-0.15077592925131486,-0.5017540153159744,1.613148049789865,-1.142327166182432,-0.7722577547913748,5.6569309364282425,-0.1940306860173823,0.31303318522898527,-1.0488191777371687,-0.022088097488964575,-0.36882191692968064,0.10496721166567786,1.4329258820598159,-0.412958796825298,-0.8637791771530676,-0.10770002139860704,0.10496721166567786,0.6361522503407359,1.5414559276361184,0.4760956266149155,0.6361522503407359,-0.546410842239735 3367 Glycoside hydrolase superfamily [IPR017853] 8 16 3.54504940317162 0.0003925395057517 Q9BTY2,P04066,P07686,O00462,P06865,P54802,P06280,P10253 Sequence InterPro Superfamily interpro_homologous_superfamily 4,6,103,40,47,54,23,59 40,2946,841,6,23,47,103,1464,59,164,440,54,2091,2021,4,1286 3.1081955602316613,-0.8179346882917339,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,1.719723884747831,0.020446217421404334,2.4362503004565204,1.3964785412072227,0.754312439228042,2.664757267155283,-0.2810734678085235,-0.23746346936348223,5.6569309364282425,0.14695211780225223 3367 Receptor 10 28 3.524072808393963 0.0004249674589791 Q9ULC4,Q14118,Q8WTV0,Q13641,A6NIH7,Q567V2,P11717,Q6YHU6,Q14108,Q9UQB8 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 243,327,110,141,137,93,53,279,27,29 137,1556,1558,959,2985,786,1308,1309,53,592,1916,141,27,327,1943,93,1786,1411,279,110,2546,335,884,1083,1721,1648,243,29 1.5054130123499248,-0.022088097488964575,-0.022088097488964575,0.31303318522898527,-0.8637791771530676,0.4356160170646649,0.10496721166567786,0.10496721166567786,2.664757267155283,0.5964120554641071,-0.1940306860173823,1.5054130123499248,3.6248188309031892,0.9478531474732188,-0.1940306860173823,1.8948765913387664,-0.10770002139860704,0.06279828060143189,1.0620389315076852,1.6843250163853651,-0.5017540153159744,0.9478531474732188,0.3949453920319386,0.27179356591045745,-0.06480379588709152,-0.022088097488964575,1.1748381597601374,3.535260987655072 3367 Steroid metabolism 7 26 3.478011557121387 0.0005051481446505 Q15392,Q9UBM7,Q14739,Q15125,O15118,P61916,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 0,1,38,7,81,25,30 81,2501,2070,841,2731,1832,361,30,1762,25,1686,3339,1185,645,1252,38,7,3075,0,2024,446,157,1714,1,831,2713 2.032866242545018,-0.5017540153159744,-0.2810734678085235,0.3949453920319386,-0.6362392226649662,-0.15077592925131486,0.8709321917690549,3.4751842548839553,-0.10770002139860704,3.772633277255873,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,-0.06480379588709152,6.354521266861696,0.4356160170646649,-0.5912394888767456 3367 Nervous system process 28 106 3.476692165211032 0.0005076402994166 Q7L576,O14773,Q9HCK8,P42574,P05067,Q13641,P63173,Q99538,Q9H2P0,Q92542,Q14108,Q9UQB8,P53634,Q9NPQ8,P50897,P17900,Q9BX67,P43034,P10253,Q14118,P80404,Q9ULX3,Q99996,Q9Y5L4,Q99808,P42858,P07686,P42345 Processes and pathways GO Biological process msigdb_gobp 263,2,402,260,14,141,140,20,426,159,27,29,274,427,35,46,313,415,59,327,65,72,79,82,225,100,103,107 2842,2944,433,2,1026,1977,2846,1738,2722,2652,2425,2948,630,3090,1984,1904,2428,2792,2724,1034,841,464,3150,14,1309,2157,103,59,1667,2990,46,1831,1471,672,3126,2950,1670,2443,2593,1180,107,260,100,415,3360,2913,1052,1323,35,1325,1115,274,2370,1055,140,3271,1849,65,603,2920,2182,2744,1770,2868,2526,1122,141,27,327,1604,1779,2096,3102,1259,691,1697,919,263,2191,2611,2289,1792,1703,159,1137,3109,1712,1074,3297,20,225,79,2703,313,2211,1007,426,402,427,1722,72,890,1015,29,82,838 -0.7267490661171271,-0.8179346882917339,0.754312439228042,5.884770299255648,0.27179356591045745,-0.23746346936348223,-0.7267490661171271,-0.10770002139860704,-0.6362392226649662,-0.5912394888767456,-0.4572697498231123,-0.8179346882917339,0.5564909583357176,-1.0023112020703986,-0.23746346936348223,-0.1940306860173823,-0.4572697498231123,-0.6814093200124656,-0.6362392226649662,0.27179356591045745,0.3949453920319386,0.7150999985878068,-1.0954913801193207,4.815860976496678,0.10496721166567786,-0.3248598804887178,1.719723884747831,2.4362503004565204,-0.06480379588709152,-0.8637791771530676,3.014617485988229,-0.15077592925131486,0.020446217421404334,0.51638636702171,-1.0488191777371687,-0.8179346882917339,-0.06480379588709152,-0.4572697498231123,-0.546410842239735,0.18875209347989597,1.6843250163853651,1.099790142352336,1.7549981936289338,0.7933537558921767,-3.517712506631267,-0.7722577547913748,0.27179356591045745,0.10496721166567786,3.2625005214835268,0.10496721166567786,0.23036622014532987,1.0620389315076852,-0.412958796825298,0.27179356591045745,1.5054130123499248,-1.426742025084107,-0.15077592925131486,2.2364769766120918,0.5964120554641071,-0.7722577547913748,-0.3248598804887178,-0.6362392226649662,-0.10770002139860704,-0.7267490661171271,-0.5017540153159744,0.23036622014532987,1.5054130123499248,3.6248188309031892,0.9478531474732188,-0.022088097488964575,-0.10770002139860704,-0.2810734678085235,-1.0023112020703986,0.14695211780225223,0.51638636702171,-0.06480379588709152,0.3540841185619894,1.099790142352336,-0.3248598804887178,-0.546410842239735,-0.36882191692968064,-0.10770002139860704,-0.06480379588709152,1.4329258820598159,0.23036622014532987,-1.0023112020703986,-0.06480379588709152,0.27179356591045745,-1.5711078846200432,3.9186948792031995,1.212138715175788,2.0670777141599412,-0.5912394888767456,0.9860724317343753,-0.3248598804887178,0.31303318522898527,0.7933537558921767,0.8322262551325478,0.7933537558921767,-0.06480379588709152,2.1351656880009666,0.3949453920319386,0.31303318522898527,3.535260987655072,2.032866242545018,0.4356160170646649 3367 Serine hydrolase activity 6 19 3.4585541627752923 0.0005430830648864 O14773,P10619,Q9HB40,O75976,Q9H3G5,P42785 Functions GO Molecular function msigdb_gomf 2,68,9,45,19,31 2,45,68,2160,2352,1581,31,2595,1587,274,975,2532,92,2604,2461,1786,2285,19,9 5.884770299255648,3.014617485988229,2.1690444425785262,-0.3248598804887178,-0.412958796825298,-0.022088097488964575,3.4450326941058216,-0.546410842239735,-0.022088097488964575,1.0620389315076852,0.31303318522898527,-0.5017540153159744,1.8948765913387664,-0.546410842239735,-0.4572697498231123,-0.10770002139860704,-0.36882191692968064,3.9766430116579654,5.321323717121585 3367 Secondary alcohol metabolic process 9 43 3.4544057344438244 0.0005515069783805 Q15392,Q9UBM7,Q14739,Q15125,Q8WTV0,P05067,O15118,P61916,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,38,7,110,14,81,25,30 81,2335,3278,2501,2070,841,14,1572,2731,2991,1832,1579,361,30,3069,215,3257,2003,3258,1114,1762,2807,25,1686,3339,1185,645,1252,1857,38,370,2922,7,3075,0,2024,446,157,110,2400,2887,1,831 2.032866242545018,-0.412958796825298,-1.4747054833332776,-0.5017540153159744,-0.2810734678085235,0.3949453920319386,4.815860976496678,-0.022088097488964575,-0.6362392226649662,-0.8637791771530676,-0.15077592925131486,-0.022088097488964575,0.8709321917690549,3.4751842548839553,-0.9559681035265681,1.212138715175788,-1.378937844623164,-0.23746346936348223,-1.378937844623164,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,3.772633277255873,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,-0.15077592925131486,3.1701628794451158,0.8709321917690549,-0.7722577547913748,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,1.6843250163853651,-0.412958796825298,-0.7267490661171271,6.354521266861696,0.4356160170646649 3367 Abnormal circulating lipid concentration 12 79 3.446988422752443 0.0005668728735046 Q15392,Q9UBM7,O43933,Q9NZC9,Q14739,Q15125,Q15904,P07602,P06280,P61916,P11310,P37268 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,1,96,97,38,7,48,17,23,25,91,30 497,1302,1104,1561,96,2985,1980,725,1904,2151,668,3148,23,1169,17,2248,91,2437,2860,1234,1477,1579,1580,440,3039,30,2168,2354,100,3178,509,2003,1840,1393,1482,2363,2175,2176,973,2520,25,2089,1183,3301,912,1774,3272,1123,38,3302,7,0,2024,446,420,48,3216,2381,1343,920,421,1873,1270,3364,1517,3201,2209,2777,2633,97,162,1,710,2567,2570,287,774,2897,837 0.6757140740040977,0.10496721166567786,0.23036622014532987,-0.022088097488964575,1.8251785328251016,-0.8637791771530676,-0.23746346936348223,0.4760956266149155,-0.1940306860173823,-0.3248598804887178,0.51638636702171,-1.0954913801193207,3.860476447122193,0.18875209347989597,4.3750256940936305,-0.36882191692968064,1.8948765913387664,-0.4572697498231123,-0.7267490661171271,0.14695211780225223,0.020446217421404334,-0.022088097488964575,-0.022088097488964575,0.754312439228042,-0.9097905400273109,3.4751842548839553,-0.3248598804887178,-0.412958796825298,1.7549981936289338,-1.142327166182432,0.6757140740040977,-0.23746346936348223,-0.15077592925131486,0.06279828060143189,0.020446217421404334,-0.412958796825298,-0.3248598804887178,-0.3248598804887178,0.31303318522898527,-0.5017540153159744,3.772633277255873,-0.2810734678085235,0.18875209347989597,-1.6195456688999854,0.3540841185619894,-0.10770002139860704,-1.426742025084107,0.23036622014532987,3.1701628794451158,-1.6195456688999854,5.347423495313898,9.266342596549883,-0.23746346936348223,0.754312439228042,0.7933537558921767,2.888645998928826,-1.2364869532593843,-0.412958796825298,0.10496721166567786,0.3540841185619894,0.7933537558921767,-0.15077592925131486,0.14695211780225223,-5.962712518670952,0.020446217421404334,-1.1893259001279373,-0.3248598804887178,-0.6362392226649662,-0.546410842239735,1.8251785328251016,1.4329258820598159,6.354521266861696,0.51638636702171,-0.5017540153159744,-0.5017540153159744,1.0620389315076852,0.4760956266149155,-0.7267490661171271,0.4356160170646649 3367 Predicted secreted proteins 14 48 3.439950628508675 0.0005818203120442 P55145,P02786,Q9BTY2,Q9UM22,Q9HB40,Q08380,O94813,P05067,O00584,O60888,Q9BUR5,P61916,P14174,O14786 Functions Protein Atlas Protein class protein_atlas_protein_class 154,67,4,8,9,11,194,14,18,50,85,25,116,127 18,127,960,50,3238,194,67,2155,14,2157,2986,1038,1667,116,542,2345,3241,321,507,1674,1586,640,154,25,2961,365,3155,911,11,233,2453,1855,2188,3219,3316,527,3275,4,85,313,1151,3081,9,944,1895,8,3361,774 4.120355977593298,1.5773671103553362,0.31303318522898527,2.793240616952005,-1.3312935370263337,1.2863020037686608,2.202814512277326,-0.3248598804887178,4.815860976496678,-0.3248598804887178,-0.8637791771530676,0.27179356591045745,-0.06480379588709152,1.613148049789865,0.6361522503407359,-0.412958796825298,-1.3312935370263337,0.9478531474732188,0.6757140740040977,-0.06480379588709152,-0.022088097488964575,0.5564909583357176,1.4329258820598159,3.772633277255873,-0.8179346882917339,0.8709321917690549,-1.0954913801193207,0.3540841185619894,5.137248975932357,1.1748381597601374,-0.4572697498231123,-0.15077592925131486,-0.3248598804887178,-1.2364869532593843,-1.7657985305992057,0.6757140740040977,-1.426742025084107,5.6569309364282425,1.9985415804284918,0.9860724317343753,0.23036622014532987,-0.9559681035265681,5.321323717121585,0.3540841185619894,-0.15077592925131486,5.347423495313898,-3.571760957557815,0.4760956266149155 3367 Abnormal conjunctiva morphology 7 29 3.43491004058929 0.0005927505650533 P02786,P10619,Q14739,P04066,O00462,P01889,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 67,68,38,6,40,84,23 40,1228,84,67,6,1378,23,68,1987,1042,671,2349,1994,2860,2733,2509,597,547,735,1771,2376,104,38,1860,1203,1205,2476,3085,944 3.1081955602316613,0.14695211780225223,1.9985415804284918,2.202814512277326,5.477203395245907,0.06279828060143189,3.860476447122193,2.1690444425785262,-0.23746346936348223,0.27179356591045745,0.51638636702171,-0.412958796825298,-0.23746346936348223,-0.7267490661171271,-0.6362392226649662,-0.5017540153159744,0.5964120554641071,0.6361522503407359,0.4760956266149155,-0.10770002139860704,-0.412958796825298,1.719723884747831,3.1701628794451158,-0.15077592925131486,0.18875209347989597,0.18875209347989597,-0.4572697498231123,-0.9559681035265681,0.3540841185619894 3367 Protein processing 11 42 3.4288676658643764 0.0006061049777967 Q15392,O75503,Q96F07,O75976,Q92896,P42892,Q8NCM8,Q99538,Q92542,Q2T9J0,P35579 Processes and pathways GO Biological process msigdb_gobp 0,3,111,45,78,16,181,20,159,92,245 1976,2649,1982,3,1904,45,2502,2795,2585,2986,503,1992,3295,245,260,1917,16,907,2178,975,1772,2373,3101,0,92,2461,2821,3103,181,1954,159,78,111,2766,2208,20,3188,2048,622,2320,2322,2493 -0.23746346936348223,-0.5912394888767456,-0.23746346936348223,5.682423722639393,-0.1940306860173823,3.014617485988229,-0.5017540153159744,-0.6814093200124656,-0.546410842239735,-0.8637791771530676,0.6757140740040977,-0.23746346936348223,-1.5711078846200432,1.1373892537486945,1.099790142352336,-0.1940306860173823,4.4588127644301565,0.3540841185619894,-0.3248598804887178,0.31303318522898527,-0.10770002139860704,-0.412958796825298,-1.0023112020703986,9.266342596549883,1.8948765913387664,-0.4572697498231123,-0.6814093200124656,-1.0023112020703986,1.3598932144259221,-0.1940306860173823,1.4329258820598159,2.0670777141599412,1.6843250163853651,-0.6362392226649662,-0.3248598804887178,3.9186948792031995,-1.142327166182432,-0.23746346936348223,0.5964120554641071,-0.36882191692968064,-0.36882191692968064,-0.4572697498231123 3367 Sterol metabolism 7 25 3.4260655092009813 0.0006123926642898 Q15392,Q9UBM7,Q14739,Q15125,O15118,P61916,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 0,1,38,7,81,25,30 81,2501,2070,841,2731,1832,361,30,1762,25,1686,3339,1185,645,1252,38,7,3075,0,2024,446,157,1,831,2713 2.032866242545018,-0.5017540153159744,-0.2810734678085235,0.3949453920319386,-0.6362392226649662,-0.15077592925131486,0.8709321917690549,3.4751842548839553,-0.10770002139860704,3.772633277255873,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,6.354521266861696,0.4356160170646649,-0.5912394888767456 3367 Cholesterol metabolism 7 24 3.416080088414929 0.0006352955966975 Q15392,Q9UBM7,Q14739,Q15125,O15118,P61916,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 0,1,38,7,81,25,30 81,2501,2070,841,2731,1832,361,30,1762,25,1686,3339,1185,645,1252,38,7,3075,0,2024,446,157,1,831 2.032866242545018,-0.5017540153159744,-0.2810734678085235,0.3949453920319386,-0.6362392226649662,-0.15077592925131486,0.8709321917690549,3.4751842548839553,-0.10770002139860704,3.772633277255873,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,6.354521266861696,0.4356160170646649 3367 Abnormality of the upper respiratory tract 16 104 3.4003901234852703 0.0006728977334564 Q9UBM7,P41229,P04066,Q14739,Q13510,P16278,O00754,P15586,P13051,P27635,P07602,Q8NCM8,P01889,P54802,P60891,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,33,6,38,104,164,44,13,163,195,17,181,84,54,24,162 666,44,2573,497,1822,3146,1558,2576,1228,2722,1167,2725,2066,2903,2794,1825,84,3148,6,2582,3193,17,731,2072,1748,163,13,164,2991,1109,1752,195,2860,2076,1319,3214,1581,2593,469,636,33,2513,3315,1918,1919,906,735,3305,599,548,2007,736,54,2262,2008,24,1846,978,2268,2182,2963,1490,1120,2376,234,104,1856,1604,38,1690,2188,1780,420,371,2533,3246,2924,1409,1949,1343,1791,181,2294,2197,2548,2549,1423,1273,311,2550,1799,349,1523,530,1007,2774,426,1361,2134,162,1,2637,2980,2642 0.51638636702171,3.014617485988229,-0.546410842239735,0.6757140740040977,-0.15077592925131486,-1.0954913801193207,-0.022088097488964575,-0.546410842239735,0.14695211780225223,-0.6362392226649662,0.18875209347989597,-0.6362392226649662,-0.2810734678085235,-0.7722577547913748,-0.6814093200124656,-0.15077592925131486,1.9985415804284918,-1.0954913801193207,5.477203395245907,-0.546410842239735,-1.1893259001279373,4.3750256940936305,0.4760956266149155,-0.2810734678085235,-0.10770002139860704,1.3964785412072227,4.896921049154351,1.3964785412072227,-0.8637791771530676,0.23036622014532987,-0.10770002139860704,1.2863020037686608,-0.7267490661171271,-0.2810734678085235,0.10496721166567786,-1.2364869532593843,-0.022088097488964575,-0.546410842239735,0.7150999985878068,0.5564909583357176,3.3236578103542245,-0.5017540153159744,-1.7657985305992057,-0.1940306860173823,-0.1940306860173823,0.3540841185619894,0.4760956266149155,-1.6681404132370228,0.5964120554641071,0.6361522503407359,-0.23746346936348223,0.4760956266149155,2.664757267155283,-0.36882191692968064,-0.23746346936348223,3.8312646321143324,-0.15077592925131486,0.31303318522898527,-0.36882191692968064,-0.3248598804887178,-0.8179346882917339,0.020446217421404334,0.23036622014532987,-0.412958796825298,1.1748381597601374,1.719723884747831,-0.15077592925131486,-0.022088097488964575,3.1701628794451158,-0.06480379588709152,-0.3248598804887178,-0.10770002139860704,0.7933537558921767,0.8709321917690549,-0.5017540153159744,-1.3312935370263337,-0.7722577547913748,0.06279828060143189,-0.1940306860173823,0.10496721166567786,-0.10770002139860704,1.3598932144259221,-0.36882191692968064,-0.3248598804887178,-0.5017540153159744,-0.5017540153159744,0.06279828060143189,0.14695211780225223,0.9860724317343753,-0.5017540153159744,-0.10770002139860704,0.909473770504105,0.020446217421404334,0.6757140740040977,0.31303318522898527,-0.6362392226649662,0.7933537558921767,0.10496721166567786,-0.2810734678085235,1.4329258820598159,6.354521266861696,-0.546410842239735,-0.8179346882917339,-0.546410842239735 3367 Membrane lipid metabolic process 14 35 3.3843110561680563 0.000713571125309 P50897,P04066,Q99805,P07686,P16278,Q13510,Q96G23,P17900,P06865,P07602,Q9H490,P06280,Q8NCC3,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 35,6,202,103,164,104,143,46,47,17,284,23,60,162 1025,1659,2651,668,841,6,23,47,17,103,164,46,1110,3333,2164,35,2268,3131,645,104,2460,3356,60,1955,1517,143,2041,759,202,284,493,336,162,767,2412 0.27179356591045745,-0.06480379588709152,-0.5912394888767456,0.51638636702171,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,1.3964785412072227,3.014617485988229,0.23036622014532987,-2.1124650811200967,-0.3248598804887178,3.2625005214835268,-0.36882191692968064,-1.0488191777371687,0.5564909583357176,1.719723884747831,-0.4572697498231123,-2.77585155562055,2.3368292667835435,-0.1940306860173823,0.020446217421404334,1.5054130123499248,-0.23746346936348223,0.4760956266149155,1.2863020037686608,1.0620389315076852,0.7150999985878068,0.9478531474732188,1.4329258820598159,0.4760956266149155,-0.412958796825298 3367 Signaling by robo receptors 47 138 3.3795598699077387 0.0007260199265366 P36578,Q07020,Q13459,Q02878,P62841,P63173,P62424,P61353,P28072,P83731,P50914,P61289,P46777,P18077,P46779,P46782,P42766,P18621,P62917,P40429,Q14118,Q15369,P46778,P25398,P62899,P61313,P62847,P27635,O94813,P84098,Q02543,P61927,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,O14786 Processes and pathways Reactome Pathways msigdb_reactome 133,134,262,366,139,140,276,275,272,155,293,295,292,165,167,178,177,303,188,306,327,331,186,70,198,74,197,195,194,323,220,219,218,345,102,108,232,231,230,229,364,363,360,119,118,247,127 1297,2843,2235,1737,127,2237,1455,2333,2850,500,194,2797,2584,731,1230,2159,2729,2730,3194,360,2346,165,591,303,504,1833,70,2254,2351,2255,674,1043,195,2075,2860,272,1577,1315,595,1755,969,2512,133,2593,3095,118,306,177,3243,108,292,186,167,1113,178,3227,416,1677,639,1924,2359,2517,293,1238,2519,851,1242,1117,229,910,295,74,275,218,219,1054,2665,3230,345,680,3072,854,230,1594,855,794,795,2521,276,2743,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,1245,140,155,232,323,1768,220,366,515,2016,134,2372,2375,1333,262,1059,327,914,1858,804,331,3003,1189,1199,2697,1431,2555,1534,1213,1548,1817,102,2418 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3367 Ribosome 51 142 3.365526663517365 0.0007639768305418 P36578,Q07020,P62841,P63173,P62851,P62424,P61353,P83731,P82664,P50914,P46777,P18077,P46779,P47914,P46782,P42766,P18621,P62917,P27695,P40429,P46778,Q9BYC9,P25398,P62899,P61313,P62847,P27635,P84098,Q02543,Q5T653,P61927,Q567V2,P61513,P62241,Q9Y3U8,Q9NVS2,Q92616,P46776,P83881,P62888,P62266,P61247,Q9P015,P62750,P09001,P15880,P62753,P39023,P63244,P62910,Q02878 Localization GO Cellular component msigdb_gocc 133,134,139,140,389,276,275,155,278,293,292,165,167,416,178,177,303,188,304,306,186,204,70,198,74,197,195,323,220,221,219,93,218,345,102,242,238,108,232,231,230,229,386,363,359,360,119,118,248,247,366 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3367 Influenza infection 44 124 3.364934644766116 0.0007656179168886 P36578,Q07020,P62841,P63173,P62851,Q5SRE5,P62424,P61353,P83731,P50914,P46777,P09496,P18077,P46779,P46782,P42766,P18621,P62917,P40429,P46778,P25398,P62899,P61313,P62847,P27635,P84098,Q92621,Q02543,P61927,P61513,P62241,Q9Y3U8,P46776,P83881,P62888,P62266,P61247,P62861,P62750,P15880,P62753,P39023,P62910,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,139,140,389,395,276,275,155,293,292,412,165,167,178,177,303,188,306,186,70,198,74,197,195,323,224,220,219,218,345,102,108,232,231,230,229,364,363,360,119,118,247,366 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3367 Clumsiness 7 22 3.3431021439599418 0.0008284739864106 O14773,O75503,P42858,Q13510,O00754,P07602,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,3,100,104,44,17,162 44,2,497,1301,1901,3,730,17,413,847,1997,100,2920,234,104,2674,1862,1613,1075,1721,162,1442 3.014617485988229,5.884770299255648,0.6757140740040977,0.10496721166567786,-0.1940306860173823,5.682423722639393,0.4760956266149155,4.3750256940936305,0.7933537558921767,0.3949453920319386,-0.23746346936348223,1.7549981936289338,-0.7722577547913748,1.1748381597601374,1.719723884747831,-0.5912394888767456,-0.15077592925131486,-0.022088097488964575,0.27179356591045745,-0.06480379588709152,1.4329258820598159,0.06279828060143189 3367 Amide binding 14 104 3.337506702763341 0.0008453368292218 Q15392,Q9UIQ6,O14773,Q9NXR7,Q9UM22,P04439,P55899,P62942,Q8WTV0,P42892,P07602,P01889,Q07954,Q13427 Functions GO Molecular function msigdb_gomf 0,32,2,161,8,73,43,75,110,16,17,84,120,122 2495,2648,2944,894,1162,1163,2,1558,1662,1105,1030,3147,3033,2581,84,73,2430,1035,17,2071,412,1039,213,467,542,1473,3037,2993,3241,673,593,2800,2950,1112,1317,2737,361,734,1836,2354,2355,16,1583,676,3228,597,2003,1051,1322,547,2998,3300,1587,1844,43,1846,679,2917,75,1595,603,2918,2452,2181,2962,120,2744,2816,2184,122,2454,2526,2528,1335,0,2824,423,110,2202,1709,2038,1520,564,312,1355,3286,759,3017,1640,426,1962,3142,2777,161,944,162,1724,3344,32,8,1367,772,2897,1449 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3367 Alcohol biosynthetic process 7 38 3.322671067783661 0.0008915998296443 Q15392,Q9UBM7,Q14739,Q15125,Q13510,Q16850,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,38,7,104,157,30 2420,1025,1659,1977,2501,2581,2070,841,1570,1572,2731,2991,1175,2258,1388,30,3069,215,1114,1762,2807,852,3339,1185,645,104,1252,38,7,3075,0,2024,446,2820,157,2480,2312,1 -0.4572697498231123,0.27179356591045745,-0.06480379588709152,-0.23746346936348223,-0.5017540153159744,-0.546410842239735,-0.2810734678085235,0.3949453920319386,-0.022088097488964575,-0.022088097488964575,-0.6362392226649662,-0.8637791771530676,0.18875209347989597,-0.36882191692968064,0.06279828060143189,3.4751842548839553,-0.9559681035265681,1.212138715175788,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,0.3949453920319386,-2.3139063625418146,0.18875209347989597,0.5564909583357176,1.719723884747831,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,-0.6814093200124656,1.4329258820598159,-0.4572697498231123,-0.36882191692968064,6.354521266861696 3367 Glycosphingolipid metabolism 8 15 3.313319156696225 0.0009219570786007 P10619,P07686,Q13510,P17900,P06865,P07602,P06280,Q9NZJ7 Processes and pathways Reactome Pathways msigdb_reactome 68,103,104,46,47,17,23,162 1898,1301,841,23,47,17,103,68,413,164,46,104,2626,493,162 -0.1940306860173823,0.10496721166567786,0.3949453920319386,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,2.1690444425785262,0.7933537558921767,1.3964785412072227,3.014617485988229,1.719723884747831,-0.546410842239735,0.7150999985878068,1.4329258820598159 3367 Sphingolipid metabolic process 11 27 3.297052574237763 0.0009770521014589 P50897,P07686,Q13510,P16278,Q96G23,P17900,P06865,P07602,P06280,Q8NCC3,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 35,103,104,164,143,46,47,17,23,60,162 1025,1659,668,841,23,47,17,103,164,46,1110,3333,2164,35,2268,3131,645,104,2460,60,143,202,493,336,162,767,2412 0.27179356591045745,-0.06480379588709152,0.51638636702171,0.3949453920319386,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,1.3964785412072227,3.014617485988229,0.23036622014532987,-2.1124650811200967,-0.3248598804887178,3.2625005214835268,-0.36882191692968064,-1.0488191777371687,0.5564909583357176,1.719723884747831,-0.4572697498231123,2.3368292667835435,1.5054130123499248,1.2863020037686608,0.7150999985878068,0.9478531474732188,1.4329258820598159,0.4760956266149155,-0.412958796825298 3367 Hallucinations 12 52 3.2863313777711327 0.0010150152440611 P19022,P21953,O75503,P50897,Q709C8,P42858,O00754,Q13501,P05067,P07602,Q9NZJ7,O96008 Drugs and Diseases Human Phenotype Ontology msigdb_hp 214,152,3,35,200,100,44,234,14,17,162,271 2235,1451,44,1301,2846,300,3,2792,271,841,14,17,2853,3125,413,732,214,152,1752,1474,1319,1999,469,100,1839,1919,35,3270,548,1841,2366,2262,851,515,797,1490,234,2531,2028,919,200,2289,876,1074,2480,2887,1534,162,2567,1160,950,2897 -0.36882191692968064,0.020446217421404334,3.014617485988229,0.10496721166567786,-0.7267490661171271,0.9860724317343753,5.682423722639393,-0.6814093200124656,1.0620389315076852,0.3949453920319386,4.815860976496678,4.3750256940936305,-0.7267490661171271,-1.0488191777371687,0.7933537558921767,0.4760956266149155,1.212138715175788,1.4329258820598159,-0.10770002139860704,0.020446217421404334,0.10496721166567786,-0.23746346936348223,0.7150999985878068,1.7549981936289338,-0.15077592925131486,-0.1940306860173823,3.2625005214835268,-1.426742025084107,0.6361522503407359,-0.15077592925131486,-0.412958796825298,-0.36882191692968064,0.3949453920319386,0.6757140740040977,0.4356160170646649,0.020446217421404334,1.1748381597601374,-0.5017540153159744,-0.23746346936348223,0.3540841185619894,1.2863020037686608,-0.36882191692968064,0.3949453920319386,0.27179356591045745,-0.4572697498231123,-0.7267490661171271,0.020446217421404334,1.4329258820598159,-0.5017540153159744,0.23036622014532987,0.3540841185619894,-0.7267490661171271 3367 Steroid biosynthetic process 9 48 3.2746845812840952 0.0010578000894105 Q15392,Q9UBM7,P48449,Q14739,Q15125,Q13510,P28288,Q16850,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,215,38,7,104,258,157,30 1821,1298,2501,2070,2796,1572,2731,1990,2991,1110,2993,1832,258,290,30,3069,215,1114,1762,2807,3339,1185,645,104,1252,1857,38,370,7,3075,0,687,607,2024,446,157,1193,1269,2763,758,1714,1639,571,1962,1358,1,1545,2713 -0.15077592925131486,0.10496721166567786,-0.5017540153159744,-0.2810734678085235,-0.6814093200124656,-0.022088097488964575,-0.6362392226649662,-0.23746346936348223,-0.8637791771530676,0.23036622014532987,-0.8637791771530676,-0.15077592925131486,1.099790142352336,1.0241336866990407,3.4751842548839553,-0.9559681035265681,1.212138715175788,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.5564909583357176,1.719723884747831,0.14695211780225223,-0.15077592925131486,3.1701628794451158,0.8709321917690549,5.347423495313898,-0.9559681035265681,9.266342596549883,0.51638636702171,0.5964120554641071,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.18875209347989597,0.14695211780225223,-0.6362392226649662,0.4760956266149155,-0.06480379588709152,-0.022088097488964575,0.6361522503407359,-0.1940306860173823,0.10496721166567786,6.354521266861696,0.020446217421404334,-0.5912394888767456 3367 Cardiomegaly 6 35 3.2538493108153723 0.0011385265541374 Q14739,P04066,P11310,P54802,P13473,P10253 Drugs and Diseases Human Phenotype Ontology msigdb_hp 38,6,91,54,26,59 1104,3173,1459,841,6,103,59,1748,91,26,2798,2588,1176,2437,847,2353,1580,2003,1393,54,1590,2089,911,2376,1494,38,3302,1692,2926,2471,2041,1714,710,2232,774 0.23036622014532987,-1.142327166182432,0.020446217421404334,0.3949453920319386,5.477203395245907,1.719723884747831,2.4362503004565204,-0.10770002139860704,1.8948765913387664,3.713721512871941,-0.6814093200124656,-0.546410842239735,0.18875209347989597,-0.4572697498231123,0.3949453920319386,-0.412958796825298,-0.022088097488964575,-0.23746346936348223,0.06279828060143189,2.664757267155283,-0.022088097488964575,-0.2810734678085235,0.3540841185619894,-0.412958796825298,0.020446217421404334,3.1701628794451158,-1.6195456688999854,-0.06480379588709152,-0.7722577547913748,-0.4572697498231123,-0.23746346936348223,-0.06480379588709152,0.51638636702171,-0.3248598804887178,0.4760956266149155 3367 Ribosomal large subunit biogenesis 30 61 3.2514841107761296 0.0011480419242244 P63173,Q8TDN6,P62424,Q99848,Q9BZE4,P83731,Q9NWT1,P50914,P46777,Q5SY16,P18077,P46087,P42766,O76021,Q9H7B2,O00541,O95478,P55769,Q9BYC9,P27635,Q9NQ55,Q9UHA3,P18124,O60287,Q8IY81,Q9NU22,P62750,P39023,Q9NYY8,Q02878 Processes and pathways GO Biological process msigdb_gobp 140,422,276,567,425,155,429,293,292,308,165,545,177,539,451,535,185,63,204,195,621,496,591,586,379,241,363,118,657,366 535,1453,586,1983,539,185,2584,3193,165,591,195,118,177,545,292,293,63,1845,910,276,363,1244,2264,140,155,366,860,1336,308,1694,2029,1131,1867,379,422,567,2770,204,1887,1532,425,2707,451,1082,621,241,2131,656,943,1645,429,2134,657,1968,496,2715,2569,3266,771,892,2785 0.6361522503407359,0.020446217421404334,0.5964120554641071,-0.23746346936348223,0.6361522503407359,1.3231682601538646,-0.546410842239735,-1.1893259001279373,1.3964785412072227,0.5964120554641071,1.2863020037686608,1.613148049789865,1.3598932144259221,0.6361522503407359,1.0241336866990407,1.0241336866990407,2.2364769766120918,-0.15077592925131486,0.3540841185619894,1.0620389315076852,0.8709321917690549,0.14695211780225223,-0.36882191692968064,1.5054130123499248,1.4329258820598159,0.8709321917690549,0.3949453920319386,0.10496721166567786,0.9860724317343753,-0.06480379588709152,-0.23746346936348223,0.23036622014532987,-0.15077592925131486,0.8709321917690549,0.7933537558921767,0.6361522503407359,-0.6362392226649662,1.2863020037686608,-0.15077592925131486,0.020446217421404334,0.7933537558921767,-0.5912394888767456,0.754312439228042,0.27179356591045745,0.5964120554641071,1.1748381597601374,-0.2810734678085235,0.5564909583357176,0.3540841185619894,-0.022088097488964575,0.7933537558921767,-0.2810734678085235,0.5564909583357176,-0.1940306860173823,0.7150999985878068,-0.5912394888767456,-0.5017540153159744,-1.378937844623164,0.4760956266149155,0.3949453920319386,-0.6362392226649662 3367 Disproportionate short stature 8 30 3.2036325774473946 0.0013570554250477 Q15392,Q9UBM7,P41229,Q9NZC9,Q14739,Q15125,P16278,P42345 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,1,33,97,38,7,164,107 2060,840,3211,1167,3238,1748,164,3241,33,107,2083,3130,3272,38,1690,7,0,521,2753,1342,181,1624,349,1523,3201,1889,97,1,3022,2980 -0.2810734678085235,0.3949453920319386,-1.2364869532593843,0.18875209347989597,-1.3312935370263337,-0.10770002139860704,1.3964785412072227,-1.3312935370263337,3.3236578103542245,1.6843250163853651,-0.2810734678085235,-1.0488191777371687,-1.426742025084107,3.1701628794451158,-0.06480379588709152,5.347423495313898,9.266342596549883,0.6757140740040977,-0.6362392226649662,0.10496721166567786,1.3598932144259221,-0.022088097488964575,0.909473770504105,0.020446217421404334,-1.1893259001279373,-0.15077592925131486,1.8251785328251016,6.354521266861696,-0.8637791771530676,-0.8179346882917339 3367 Azurophil granule membrane 9 22 3.1911687677693164 0.0014169848317517 P11279,O00462,P10253,P07602,O15260,P13473,Q92542,P27105,P42785 Localization GO Cellular component msigdb_gocc 90,40,59,17,49,26,159,62,31 40,49,2426,300,3254,17,59,90,26,62,3067,31,1927,1331,690,2758,159,1878,3188,1007,162,2412 3.1081955602316613,2.793240616952005,-0.4572697498231123,0.9860724317343753,-1.378937844623164,4.3750256940936305,2.4362503004565204,1.8948765913387664,3.713721512871941,2.270032897213297,-0.9559681035265681,3.4450326941058216,-0.1940306860173823,0.10496721166567786,0.51638636702171,-0.6362392226649662,1.4329258820598159,-0.15077592925131486,-1.142327166182432,0.31303318522898527,1.4329258820598159,-0.412958796825298 3367 Abnormal tissue metabolite concentration 7 15 3.172199328562209 0.0015128912816357 O43933,Q658P3,P07686,P17900,P06865,P07602,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,36,103,46,47,17,23 1301,96,2985,23,47,17,103,413,46,2363,973,36,3047,162,1160 0.10496721166567786,1.8251785328251016,-0.8637791771530676,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,0.7933537558921767,3.014617485988229,-0.412958796825298,0.31303318522898527,3.201023198065498,-0.9097905400273109,1.4329258820598159,0.23036622014532987 3367 Polysomal ribosome 13 25 3.169133192320882 0.0015289431206073 Q02543,Q9Y3U8,Q07020,P62899,P84098,P63173,P83881,P62888,P62266,P62917,P62424,P62910,P83731 Localization GO Cellular component msigdb_gocc 220,102,134,198,323,140,232,231,230,188,276,247,155 1660,3092,230,855,276,1681,231,198,1244,247,2264,188,140,155,232,323,220,366,134,1488,1339,2284,2883,2826,102 -0.06480379588709152,-1.0023112020703986,1.1748381597601374,0.3949453920319386,1.0620389315076852,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,1.212138715175788,0.8709321917690549,1.5414559276361184,0.020446217421404334,0.10496721166567786,-0.36882191692968064,-0.7267490661171271,-0.6814093200124656,1.7549981936289338 3367 Membrane lipid catabolic process 6 12 3.16618378497548 0.001544531742788 P50897,P04066,P07686,P17900,P06865,P06280 Processes and pathways GO Biological process msigdb_gobp 35,6,103,46,47,23 668,841,6,23,47,103,46,35,2268,104,759,493 0.51638636702171,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,1.719723884747831,3.014617485988229,3.2625005214835268,-0.36882191692968064,1.719723884747831,0.4760956266149155,0.7150999985878068 3367 Protein maturation 15 68 3.1516659106206784 0.001623419045317 Q15392,Q86UY6,O75503,Q9H3K6,P62942,Q96F07,O75976,Q92896,P42892,Q8NCM8,Q99538,Q9BU23,Q92542,Q2T9J0,P35579 Processes and pathways GO Biological process msigdb_gobp 0,129,3,267,75,111,45,78,16,181,20,125,159,92,245 337,1976,2649,1982,3,1904,45,2902,2792,1744,2502,2795,2585,2986,503,3124,1992,3295,2800,245,3128,260,1917,16,2360,907,2178,75,975,912,1772,2373,1187,3283,1257,3101,0,92,2461,2821,3103,3047,1788,129,181,1954,159,78,111,2766,450,2208,20,3188,125,619,2305,824,267,2048,1292,1013,622,2320,2640,2322,2894,2493 0.909473770504105,-0.23746346936348223,-0.5912394888767456,-0.23746346936348223,5.682423722639393,-0.1940306860173823,3.014617485988229,-0.7722577547913748,-0.6814093200124656,-0.10770002139860704,-0.5017540153159744,-0.6814093200124656,-0.546410842239735,-0.8637791771530676,0.6757140740040977,-1.0488191777371687,-0.23746346936348223,-1.5711078846200432,-0.6814093200124656,1.1373892537486945,-1.0488191777371687,1.099790142352336,-0.1940306860173823,4.4588127644301565,-0.412958796825298,0.3540841185619894,-0.3248598804887178,2.0670777141599412,0.31303318522898527,0.3540841185619894,-0.10770002139860704,-0.412958796825298,0.18875209347989597,-1.4747054833332776,0.14695211780225223,-1.0023112020703986,9.266342596549883,1.8948765913387664,-0.4572697498231123,-0.6814093200124656,-1.0023112020703986,-0.9097905400273109,-0.10770002139860704,1.5773671103553362,1.3598932144259221,-0.1940306860173823,1.4329258820598159,2.0670777141599412,1.6843250163853651,-0.6362392226649662,0.754312439228042,-0.3248598804887178,3.9186948792031995,-1.142327166182432,1.613148049789865,0.5964120554641071,-0.36882191692968064,0.4356160170646649,1.099790142352336,-0.23746346936348223,0.14695211780225223,0.31303318522898527,0.5964120554641071,-0.36882191692968064,-0.546410842239735,-0.36882191692968064,-0.7267490661171271,-0.4572697498231123 3367 Steroid biosynthesis 6 23 3.149591589926809 0.0016349885009394 Q15392,Q9UBM7,Q14739,Q15125,Q16850,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 0,1,38,7,157,30 2070,2731,30,215,1762,2807,3339,1185,645,1252,38,7,3075,0,2024,446,157,1193,1269,1639,1962,1,2713 -0.2810734678085235,-0.6362392226649662,3.4751842548839553,1.212138715175788,-0.10770002139860704,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.18875209347989597,0.14695211780225223,-0.022088097488964575,-0.1940306860173823,6.354521266861696,-0.5912394888767456 3367 Alcohol metabolic process 12 81 3.1056858650592227 0.0018983827250618 Q15392,Q9UBM7,Q14739,Q15125,Q13510,Q8WTV0,Q6NUM9,P05067,O15118,Q16850,P61916,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,38,7,104,110,76,14,81,157,25,30 2420,81,1025,1659,1977,2241,2335,2651,3278,2501,3122,2581,2070,841,14,729,1570,1572,1909,2731,1989,1990,2991,1175,1832,2258,3363,1579,1388,361,30,3069,2515,215,3257,2003,3258,1482,1325,2596,1114,1762,2807,1240,852,25,1686,1934,3339,1183,1185,1772,645,104,3231,1122,1252,1857,38,370,2922,7,3075,0,2024,446,2820,157,76,333,878,172,110,2480,2400,2887,2705,2312,1,831,1093 -0.4572697498231123,2.032866242545018,0.27179356591045745,-0.06480379588709152,-0.23746346936348223,-0.36882191692968064,-0.412958796825298,-0.5912394888767456,-1.4747054833332776,-0.5017540153159744,-1.0488191777371687,-0.546410842239735,-0.2810734678085235,0.3949453920319386,4.815860976496678,0.4760956266149155,-0.022088097488964575,-0.022088097488964575,-0.1940306860173823,-0.6362392226649662,-0.23746346936348223,-0.23746346936348223,-0.8637791771530676,0.18875209347989597,-0.15077592925131486,-0.36882191692968064,-5.256126429676467,-0.022088097488964575,0.06279828060143189,0.8709321917690549,3.4751842548839553,-0.9559681035265681,-0.5017540153159744,1.212138715175788,-1.378937844623164,-0.23746346936348223,-1.378937844623164,0.020446217421404334,0.10496721166567786,-0.546410842239735,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,0.14695211780225223,0.3949453920319386,3.772633277255873,-0.06480379588709152,-0.1940306860173823,-2.3139063625418146,0.18875209347989597,0.18875209347989597,-0.10770002139860704,0.5564909583357176,1.719723884747831,-1.2838097038521317,0.23036622014532987,0.14695211780225223,-0.15077592925131486,3.1701628794451158,0.8709321917690549,-0.7722577547913748,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,-0.6814093200124656,1.4329258820598159,2.0670777141599412,0.9478531474732188,0.3949453920319386,1.3964785412072227,1.6843250163853651,-0.4572697498231123,-0.412958796825298,-0.7267490661171271,-0.5912394888767456,-0.36882191692968064,6.354521266861696,0.4356160170646649,0.27179356591045745 3367 Behavior 22 76 3.0973744894127253 0.0019524305418934 Q13330,Q9HCK8,P42574,Q13641,P05067,Q99538,Q9H2P0,Q92542,Q9NPQ8,P50897,P53985,P30536,P17900,P43034,P54802,P10253,P80404,O15118,P42858,P04179,P07686,P42345 Processes and pathways GO Biological process msigdb_gobp 517,402,260,141,14,20,426,159,427,35,294,290,46,415,54,59,65,81,100,464,103,107 2842,2944,779,81,1026,2423,1904,2428,2792,2724,787,841,3149,464,2582,14,1309,2432,2157,103,1664,1171,59,1992,46,1831,2507,1670,290,2593,1180,636,107,260,100,415,2083,1393,35,1325,294,54,2370,1849,65,515,2920,645,517,2526,141,1604,2023,3102,919,2283,2191,2192,1348,1792,159,2475,3109,1074,816,1140,2480,20,426,1153,402,427,1722,2940,2319,718 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3367 Loss of speech 7 20 3.0943439733401723 0.0019724865335937 P50897,O00754,P17900,P07602,O15118,P61916,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,44,46,17,81,25,162 44,81,1301,3173,2501,17,413,46,35,1325,1589,2262,1590,25,234,1406,2682,3112,162,2232 3.014617485988229,2.032866242545018,0.10496721166567786,-1.142327166182432,-0.5017540153159744,4.3750256940936305,0.7933537558921767,3.014617485988229,3.2625005214835268,0.10496721166567786,-0.022088097488964575,-0.36882191692968064,-0.022088097488964575,3.772633277255873,1.1748381597601374,0.06279828060143189,-0.5912394888767456,-1.0023112020703986,1.4329258820598159,-0.3248598804887178 3367 Abnormality of the cervical spine 25 108 3.08977476251973 0.00200308336054 Q07864,Q9UBM7,Q99575,P04066,Q15125,Q07020,P15586,Q92917,Q5SRE5,P61353,Q8TC12,P46777,P16278,O00754,P18077,P43034,P42766,P62899,P61313,P62847,Q9NXE4,Q9NZC9,Q12768,Q8IY37,Q2M1P5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 367,1,266,6,7,134,13,281,395,275,172,292,164,44,165,415,177,198,74,197,493,97,121,251,371 1656,2235,44,497,3211,2787,895,2788,1902,2722,1167,2068,6,1463,3065,1170,1230,466,13,164,1042,165,2348,1752,2949,1670,3066,2259,3314,3095,177,415,906,292,3227,1840,1325,3070,2007,851,910,74,275,1054,2742,680,2450,855,197,1681,198,2264,1765,3000,1685,742,2815,1769,134,367,121,797,2376,1251,1123,1406,7,1780,1259,371,395,2753,691,1865,1342,1866,251,172,2471,1624,2548,1273,281,924,2476,698,1523,927,2702,266,1805,2560,1889,2211,2484,765,493,97,1,2980,3116,948,1727,1972,2982,662,1368,3027 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3367 Cholesterol biosynthesis 6 18 3.0756630949365897 0.0021003502293677 Q15392,Q9UBM7,Q14739,Q15125,Q16850,P37268 Processes and pathways Reactome Pathways msigdb_reactome 0,1,38,7,157,30 2731,30,215,1762,2807,3339,1185,1252,1857,38,7,3075,0,2024,446,157,1002,1 -0.6362392226649662,3.4751842548839553,1.212138715175788,-0.10770002139860704,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.14695211780225223,-0.15077592925131486,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.31303318522898527,6.354521266861696 3367 Cdc42 gtpase cycle 12 36 3.075255454961113 0.0021032232621827 Q96HP0,P02786,Q658P3,Q14739,Q13459,Q13576,P46940,O75962,P63167,Q86VI3,Q9UQB8,P27105 Processes and pathways Reactome Pathways msigdb_reactome 253,67,36,38,262,235,246,358,277,222,29,62 2572,1369,459,358,67,2990,2798,62,2001,2803,246,908,2959,1117,277,2523,2375,262,235,2020,1778,38,1189,36,396,690,750,222,253,1279,1079,1810,2217,1537,29,951 -0.546410842239735,0.06279828060143189,0.7150999985878068,0.8709321917690549,2.202814512277326,-0.8637791771530676,-0.6814093200124656,2.270032897213297,-0.23746346936348223,-0.6814093200124656,1.1373892537486945,0.3540841185619894,-0.8179346882917339,0.23036622014532987,1.0620389315076852,-0.5017540153159744,-0.412958796825298,1.099790142352336,1.1748381597601374,-0.23746346936348223,-0.10770002139860704,3.1701628794451158,0.18875209347989597,3.201023198065498,0.8322262551325478,0.51638636702171,0.4760956266149155,1.212138715175788,1.1373892537486945,0.14695211780225223,0.27179356591045745,-0.10770002139860704,-0.3248598804887178,0.020446217421404334,3.535260987655072,0.3540841185619894 3367 Sphingolipid metabolism 9 25 3.065908912009911 0.0021700941470901 P10619,P07686,Q13510,Q96G23,P17900,P06865,P07602,P06280,Q9NZJ7 Processes and pathways Reactome Pathways msigdb_reactome 68,103,104,143,46,47,17,23,162 1898,1025,1659,1301,2725,668,841,23,47,17,103,68,413,164,46,1110,3333,2596,3131,104,143,2626,493,162,2412 -0.1940306860173823,0.27179356591045745,-0.06480379588709152,0.10496721166567786,-0.6362392226649662,0.51638636702171,0.3949453920319386,3.860476447122193,2.9518057266228475,4.3750256940936305,1.719723884747831,2.1690444425785262,0.7933537558921767,1.3964785412072227,3.014617485988229,0.23036622014532987,-2.1124650811200967,-0.546410842239735,-1.0488191777371687,1.719723884747831,1.5054130123499248,-0.546410842239735,0.7150999985878068,1.4329258820598159,-0.412958796825298 3367 Abnormal retinal vascular morphology 10 51 3.063138548145643 0.0021902862671889 P10619,P07686,Q13510,P04439,P17900,P06865,P07602,Q6P2Q9,Q8WYQ5,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,103,104,73,46,47,17,149,87,162 666,1300,498,1104,2335,1029,1903,1106,3090,2246,73,47,17,103,2727,68,1987,2073,164,46,844,2349,1752,847,1914,1580,2082,2911,1389,2912,2358,3258,2007,2089,1248,1185,2376,104,3302,1259,149,3012,87,526,2548,1273,1350,2211,162,710,774 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Abnormal retinal artery morphology 7 20 3.0546818660280204 0.0022529936953885 P10619,P07686,Q13510,P17900,P06865,P07602,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,103,104,46,47,17,162 498,1104,47,17,103,68,2073,164,46,1752,1580,2007,2089,104,3302,2548,1273,162,710,774 0.6757140740040977,0.23036622014532987,2.9518057266228475,4.3750256940936305,1.719723884747831,2.1690444425785262,-0.2810734678085235,1.3964785412072227,3.014617485988229,-0.10770002139860704,-0.022088097488964575,-0.23746346936348223,-0.2810734678085235,1.719723884747831,-1.6195456688999854,-0.5017540153159744,0.14695211780225223,1.4329258820598159,0.51638636702171,0.4760956266149155 3367 Endocytic vesicle membrane 10 40 3.043708526558716 0.0023368142727546 Q5KU26,P02786,P11279,P04439,Q8WTV0,P01889,P11717,Q07954,P13473,Q14108 Localization GO Cellular component msigdb_gocc 66,67,90,73,110,84,53,120,26,27 1369,1558,2149,786,1308,84,67,73,213,90,53,26,2436,592,2800,1585,908,2864,3071,2369,737,1595,796,1183,120,644,799,744,27,2189,3102,66,2539,110,923,564,350,2830,3116,1295 0.06279828060143189,-0.022088097488964575,-0.3248598804887178,0.4356160170646649,0.10496721166567786,1.9985415804284918,2.202814512277326,2.1011771507196184,1.212138715175788,1.8948765913387664,2.664757267155283,3.713721512871941,-0.4572697498231123,0.5964120554641071,-0.6814093200124656,-0.022088097488964575,0.3540841185619894,-0.7267490661171271,-0.9559681035265681,-0.412958796825298,0.4760956266149155,-0.022088097488964575,0.4356160170646649,0.18875209347989597,1.613148049789865,0.5564909583357176,0.4356160170646649,0.4760956266149155,3.6248188309031892,-0.3248598804887178,-1.0023112020703986,2.2364769766120918,-0.5017540153159744,1.6843250163853651,0.3540841185619894,0.6361522503407359,0.909473770504105,-0.6814093200124656,-1.0023112020703986,0.14695211780225223 3367 Abnormal enchondral ossification 7 30 3.0399034873170128 0.0023665397149104 O43933,Q9UBM7,Q14739,Q15125,Q9NUQ7,Q8NCM8,Q96HA7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,1,38,7,315,181,349 2060,3211,96,1167,2985,1743,1377,1748,1109,1581,1389,973,1846,1119,38,1690,7,2024,371,2533,181,1624,349,1523,927,2629,315,1,622,2642 -0.2810734678085235,-1.2364869532593843,1.8251785328251016,0.18875209347989597,-0.8637791771530676,-0.10770002139860704,0.06279828060143189,-0.10770002139860704,0.23036622014532987,-0.022088097488964575,0.06279828060143189,0.31303318522898527,-0.15077592925131486,0.23036622014532987,3.1701628794451158,-0.06480379588709152,5.347423495313898,-0.23746346936348223,0.8709321917690549,-0.5017540153159744,1.3598932144259221,-0.022088097488964575,0.909473770504105,0.020446217421404334,0.3540841185619894,-0.546410842239735,0.9860724317343753,6.354521266861696,0.5964120554641071,-0.546410842239735 3367 Cholesterol metabolism with bloch and kandutschrussell pathways 6 25 3.037395637624683 0.0023863202067595 Q15392,Q9UBM7,Q14739,Q15125,Q16850,P37268 Processes and pathways WikiPathways msigdb_wp 0,1,38,7,157,30 954,1823,1663,463,2731,2995,361,30,215,597,1762,2807,3339,1185,1252,1857,38,7,3075,0,2024,446,157,1002,1 0.31303318522898527,-0.15077592925131486,-0.06480379588709152,0.7150999985878068,-0.6362392226649662,-0.8637791771530676,0.8709321917690549,3.4751842548839553,1.212138715175788,0.5964120554641071,-0.10770002139860704,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.14695211780225223,-0.15077592925131486,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.31303318522898527,6.354521266861696 3367 Abnormal visual electrophysiology 8 48 3.025901548726879 0.002478930038706 O43933,O14773,O75503,P50897,P07602,Q6P2Q9,P60891,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,2,3,35,17,149,24,162 2,1300,498,1301,2335,96,2846,3,1106,3090,2246,17,1040,413,844,672,2082,2861,2354,3258,35,2363,307,1590,24,3308,1494,1779,2674,1259,2460,149,1866,2610,2542,172,3012,3107,526,2827,1805,2211,1641,2976,1642,1722,162,3054 5.884770299255648,0.10496721166567786,0.6757140740040977,0.10496721166567786,-0.412958796825298,1.8251785328251016,-0.7267490661171271,5.682423722639393,0.23036622014532987,-1.0023112020703986,-0.36882191692968064,4.3750256940936305,0.27179356591045745,0.7933537558921767,0.3949453920319386,0.51638636702171,-0.2810734678085235,-0.7267490661171271,-0.412958796825298,-1.378937844623164,3.2625005214835268,-0.412958796825298,0.9860724317343753,-0.022088097488964575,3.8312646321143324,-1.7168915533017404,0.020446217421404334,-0.10770002139860704,-0.5912394888767456,0.14695211780225223,-0.4572697498231123,1.469236846394831,-0.15077592925131486,-0.546410842239735,-0.5017540153159744,1.3964785412072227,-0.8637791771530676,-1.0023112020703986,0.6757140740040977,-0.6814093200124656,-0.10770002139860704,-0.3248598804887178,-0.022088097488964575,-0.8179346882917339,-0.022088097488964575,-0.06480379588709152,1.4329258820598159,-0.9097905400273109 3367 Sterol biosynthetic process 6 25 3.023866034059633 0.0024956692349911 Q15392,Q9UBM7,Q14739,Q15125,Q16850,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,38,7,157,30 2501,2070,1572,2731,2991,30,3069,215,1114,1762,2807,3339,1185,645,1252,1857,38,7,3075,0,2024,446,157,1,2713 -0.5017540153159744,-0.2810734678085235,-0.022088097488964575,-0.6362392226649662,-0.8637791771530676,3.4751842548839553,-0.9559681035265681,1.212138715175788,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.5564909583357176,0.14695211780225223,-0.15077592925131486,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,6.354521266861696,-0.5912394888767456 3367 Dementia 14 61 3.0094070667385924 0.0026175814507845 Q709C8,P42858,Q13510,P17900,P05067,P06865,P07602,O15118,Q13501,P26358,Q9NZJ7,P61916,Q14108,O96008 Drugs and Diseases Human Phenotype Ontology msigdb_hp 200,100,104,46,14,47,17,81,234,176,162,25,27,271 1451,81,1301,2846,300,2792,271,728,841,3149,465,14,47,17,2072,2341,413,46,3240,2349,2506,176,3333,847,1997,1319,3214,3177,100,1918,1325,1589,2262,25,2091,515,2182,1490,234,104,27,1604,2682,919,200,2610,876,485,1205,2202,1074,816,1075,2480,885,162,1896,950,2717,1295,2897 0.020446217421404334,2.032866242545018,0.10496721166567786,-0.7267490661171271,0.9860724317343753,-0.6814093200124656,1.0620389315076852,0.4760956266149155,0.3949453920319386,-1.0954913801193207,0.7150999985878068,4.815860976496678,2.9518057266228475,4.3750256940936305,-0.2810734678085235,-0.412958796825298,0.7933537558921767,3.014617485988229,-1.3312935370263337,-0.412958796825298,-0.5017540153159744,1.3598932144259221,-2.1124650811200967,0.3949453920319386,-0.23746346936348223,0.10496721166567786,-1.2364869532593843,-1.142327166182432,1.7549981936289338,-0.1940306860173823,0.10496721166567786,-0.022088097488964575,-0.36882191692968064,3.772633277255873,-0.2810734678085235,0.6757140740040977,-0.3248598804887178,0.020446217421404334,1.1748381597601374,1.719723884747831,3.6248188309031892,-0.022088097488964575,-0.5912394888767456,0.3540841185619894,1.2863020037686608,-0.546410842239735,0.3949453920319386,0.7150999985878068,0.18875209347989597,-0.3248598804887178,0.27179356591045745,0.4356160170646649,0.27179356591045745,-0.4572697498231123,0.3949453920319386,1.4329258820598159,-0.15077592925131486,0.3540841185619894,-0.5912394888767456,0.14695211780225223,-0.7267490661171271 3367 Cherry red spot of the macula 7 9 3.0062170807067057 0.0026452008153359 P10619,P07686,Q13510,P17900,P06865,P07602,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,103,104,46,47,17,162 47,17,103,68,2073,164,46,104,162 2.9518057266228475,4.3750256940936305,1.719723884747831,2.1690444425785262,-0.2810734678085235,1.3964785412072227,3.014617485988229,1.719723884747831,1.4329258820598159 3367 Cognition 11 34 2.99954384361109 0.0027038420628369 Q7L576,P50897,P42858,P42574,P17900,Q13641,P05067,Q99538,Q9H2P0,Q92542,Q9NPQ8 Processes and pathways GO Biological process msigdb_gobp 263,35,100,260,46,141,14,20,426,159,427 2842,2944,1026,2428,14,1309,2157,46,1831,1670,2593,1180,260,100,415,35,1325,2370,1849,2920,2526,141,3102,691,263,1792,159,3109,1712,20,1007,426,427,1722 -0.7267490661171271,-0.8179346882917339,0.27179356591045745,-0.4572697498231123,4.815860976496678,0.10496721166567786,-0.3248598804887178,3.014617485988229,-0.15077592925131486,-0.06480379588709152,-0.546410842239735,0.18875209347989597,1.099790142352336,1.7549981936289338,0.7933537558921767,3.2625005214835268,0.10496721166567786,-0.412958796825298,-0.15077592925131486,-0.7722577547913748,-0.5017540153159744,1.5054130123499248,-1.0023112020703986,0.51638636702171,1.099790142352336,-0.10770002139860704,1.4329258820598159,-1.0023112020703986,-0.06480379588709152,3.9186948792031995,0.31303318522898527,0.7933537558921767,0.7933537558921767,-0.06480379588709152 3367 IQ motif, EF-hand binding site [IPR000048] 10 13 2.981555780697869 0.0028678779606019 Q13459,Q12965,O94832,Q13576,O43795,Q9Y4I1,P35580,Q86VI3,P46940,P35579 Sequence InterPro Binding site interpro_binding_site 262,261,319,235,206,287,387,222,246,245 407,206,319,245,387,246,261,262,235,746,2191,222,287 0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.1373892537486945,1.099790142352336,1.099790142352336,1.1748381597601374,0.4760956266149155,-0.3248598804887178,1.212138715175788,1.0620389315076852 3367 Duplication of hand bones 12 58 2.9792538290014323 0.0028895130518911 Q9UBM7,Q14739,Q15125,Q07020,P62899,P61313,P62847,P18077,Q8NCM8,P42766,Q12768,P61353 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,38,7,134,198,74,197,165,181,177,121,275 2331,1902,1167,1743,1377,1230,165,1109,1752,2509,2082,3095,3128,177,292,3227,2007,736,2520,851,910,74,275,1054,680,855,197,1681,198,2264,2667,134,1772,121,1774,1119,38,2673,2674,7,371,1864,1343,2610,181,1624,2548,1273,924,1805,821,2211,2308,1,2980,3116,1220,3192 -0.412958796825298,-0.1940306860173823,0.18875209347989597,-0.10770002139860704,0.06279828060143189,0.14695211780225223,1.3964785412072227,0.23036622014532987,-0.10770002139860704,-0.5017540153159744,-0.2810734678085235,-1.0023112020703986,-1.0488191777371687,1.3598932144259221,1.0241336866990407,-1.2838097038521317,-0.23746346936348223,0.4760956266149155,-0.5017540153159744,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,-0.5912394888767456,1.5414559276361184,-0.10770002139860704,1.613148049789865,-0.10770002139860704,0.23036622014532987,3.1701628794451158,-0.5912394888767456,-0.5912394888767456,5.347423495313898,0.8709321917690549,-0.15077592925131486,0.10496721166567786,-0.546410842239735,1.3598932144259221,-0.022088097488964575,-0.5017540153159744,0.14695211780225223,0.3540841185619894,-0.10770002139860704,0.4356160170646649,-0.3248598804887178,-0.36882191692968064,6.354521266861696,-0.8179346882917339,-1.0023112020703986,0.18875209347989597,-1.142327166182432 3367 Locomotory behavior 7 28 2.974238859639621 0.0029371634067301 P80404,P50897,P07686,P05067,O15118,P54802,P10253 Processes and pathways GO Biological process msigdb_gobp 65,35,103,14,81,54,59 2842,81,2423,1904,787,3149,464,14,103,1171,59,2507,107,415,2083,35,1325,54,65,2920,517,3102,919,1348,1074,816,2480,1153 -0.7267490661171271,2.032866242545018,-0.4572697498231123,-0.1940306860173823,0.4356160170646649,-1.0954913801193207,0.7150999985878068,4.815860976496678,1.719723884747831,0.18875209347989597,2.4362503004565204,-0.5017540153159744,1.6843250163853651,0.7933537558921767,-0.2810734678085235,3.2625005214835268,0.10496721166567786,2.664757267155283,2.2364769766120918,-0.7722577547913748,0.6757140740040977,-1.0023112020703986,0.3540841185619894,0.10496721166567786,0.27179356591045745,0.4356160170646649,-0.4572697498231123,0.23036622014532987 3367 Rough endoplasmic reticulum 8 33 2.9672528526726243 0.0030047374214747 P36578,Q07020,Q5BJF2,P60059,P05067,P62266,P61353,Q9UQB8 Localization GO Cellular component msigdb_gocc 133,134,10,168,14,230,275,29 1225,960,2067,2583,670,14,1829,1993,846,2737,133,1321,168,1680,1243,275,679,230,855,1681,682,366,134,1331,519,10,2026,1954,2930,1528,2317,29,2645 0.14695211780225223,0.31303318522898527,-0.2810734678085235,-0.546410842239735,0.51638636702171,4.815860976496678,-0.15077592925131486,-0.23746346936348223,0.3949453920319386,-0.6362392226649662,1.5414559276361184,0.10496721166567786,1.3964785412072227,-0.06480379588709152,0.14695211780225223,1.0620389315076852,0.51638636702171,1.1748381597601374,0.3949453920319386,-0.06480379588709152,0.51638636702171,0.8709321917690549,1.5414559276361184,0.10496721166567786,0.6757140740040977,5.216435956950591,-0.23746346936348223,-0.1940306860173823,-0.7722577547913748,0.020446217421404334,-0.36882191692968064,3.535260987655072,-0.546410842239735 3367 Increased bone mineral density 8 29 2.966121481639364 0.0030158133944964 Q15392,Q14739,Q15125,Q13501,P51798,P54802,Q14108,Q15043 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,38,7,234,307,54,27,330 2576,1104,3148,841,1042,671,1109,1994,1580,793,307,54,2262,2089,742,1400,234,27,1856,38,330,3302,7,0,2750,349,710,3192,774 -0.546410842239735,0.23036622014532987,-1.0954913801193207,0.3949453920319386,0.27179356591045745,0.51638636702171,0.23036622014532987,-0.23746346936348223,-0.022088097488964575,0.4356160170646649,0.9860724317343753,2.664757267155283,-0.36882191692968064,-0.2810734678085235,0.4760956266149155,0.06279828060143189,1.1748381597601374,3.6248188309031892,-0.15077592925131486,3.1701628794451158,0.9478531474732188,-1.6195456688999854,5.347423495313898,9.266342596549883,-0.6362392226649662,0.909473770504105,0.51638636702171,-1.142327166182432,0.4760956266149155 3367 Abnormality of head blood vessel 7 22 2.951956787075197 0.0031576711785195 P10619,P07686,Q13510,P17900,P06865,P07602,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,103,104,46,47,17,162 497,498,1104,47,17,103,68,2073,164,46,1752,1580,793,2007,2089,104,3302,2548,1273,162,710,774 0.6757140740040977,0.6757140740040977,0.23036622014532987,2.9518057266228475,4.3750256940936305,1.719723884747831,2.1690444425785262,-0.2810734678085235,1.3964785412072227,3.014617485988229,-0.10770002139860704,-0.022088097488964575,0.4356160170646649,-0.23746346936348223,-0.2810734678085235,1.719723884747831,-1.6195456688999854,-0.5017540153159744,0.14695211780225223,1.4329258820598159,0.51638636702171,0.4760956266149155 3367 Rrna processing 75 169 2.9518845123310027 0.0031584103433308 P36578,Q07020,Q9NR30,P62841,P63173,Q9H9L3,P62851,Q99848,P62424,P61353,Q9BVJ6,P83731,P50914,Q9NW13,P46777,Q9UI30,Q5SY16,P18077,P46779,P46087,Q9H583,P47914,P46782,P42766,P18621,O95059,P62917,O15213,O00541,P40429,P62861,P55769,P46778,Q7L0Y3,P62829,P25398,Q9ULX3,P62899,P61313,P62847,P27635,P78345,O75691,P84098,Q9NXF1,Q9NQZ2,Q02543,Q13895,Q14692,P61927,P18124,P61513,P62241,Q8IY81,Q9Y3U8,P15880,P32969,Q14690,P62701,P46776,P83881,P62888,P62266,Q96G21,P61247,Q8IY37,Q969X6,Q9NXG2,Q2NL82,P62750,P62753,P39023,P62910,Q9H4L4,Q02878 Processes and pathways Reactome Pathways msigdb_reactome 133,134,403,139,140,285,389,567,276,275,424,155,293,575,292,578,308,165,167,545,314,416,178,177,303,540,188,57,535,306,364,63,186,556,550,70,72,198,74,197,195,322,207,323,494,353,220,604,346,219,591,218,345,379,102,360,595,473,471,108,232,231,230,651,229,251,648,385,372,363,119,118,247,531,366 3061,535,2496,2718,1557,57,1104,2720,1228,207,667,540,2797,2584,1230,2159,360,165,591,303,3151,1753,1833,70,1043,195,1315,595,969,133,3095,118,306,2514,177,545,108,292,186,167,1113,178,3227,416,639,293,63,1326,851,229,910,74,275,218,219,1054,345,680,3072,854,230,1594,855,794,795,276,471,363,119,550,139,197,389,1681,364,231,198,1244,247,2264,188,140,681,322,1596,155,232,323,1247,220,366,1769,134,2269,1121,2967,604,860,473,346,2187,1127,2274,372,2535,308,1785,556,3351,2466,251,379,2611,1703,1135,2472,995,648,651,3274,1714,567,1282,1803,1078,424,653,2627,2707,935,1535,2831,531,314,2309,3204,285,2311,1361,1890,1290,353,403,1644,827,3143,575,2134,494,385,2634,1156,3336,578,72,1726,1971,2569,891,3026,1017,1222,2841,2896,2492,102,2785,2328,3060 -0.9559681035265681,0.6361522503407359,-0.5017540153159744,-0.6362392226649662,-0.022088097488964575,2.50202672361432,0.23036622014532987,-0.6362392226649662,0.14695211780225223,1.249292736644776,0.51638636702171,0.6361522503407359,-0.6814093200124656,-0.546410842239735,0.14695211780225223,-0.3248598804887178,0.8709321917690549,1.3964785412072227,0.5964120554641071,0.9860724317343753,-1.0954913801193207,-0.10770002139860704,-0.15077592925131486,2.1351656880009666,0.27179356591045745,1.2863020037686608,0.10496721166567786,0.5964120554641071,0.31303318522898527,1.5414559276361184,-1.0023112020703986,1.613148049789865,0.9860724317343753,-0.5017540153159744,1.3598932144259221,0.6361522503407359,1.6843250163853651,1.0241336866990407,1.3231682601538646,1.3964785412072227,0.23036622014532987,1.3598932144259221,-1.2838097038521317,0.7933537558921767,0.5564909583357176,1.0241336866990407,2.2364769766120918,0.10496721166567786,0.3949453920319386,1.1748381597601374,0.3540841185619894,2.0670777141599412,1.0620389315076852,1.212138715175788,1.212138715175788,0.27179356591045745,0.909473770504105,0.51638636702171,-0.9559681035265681,0.3949453920319386,1.1748381597601374,-0.022088097488964575,0.3949453920319386,0.4356160170646649,0.4356160170646649,1.0620389315076852,0.7150999985878068,0.8709321917690549,1.613148049789865,0.6361522503407359,1.5054130123499248,1.2863020037686608,0.8322262551325478,-0.06480379588709152,0.8709321917690549,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,0.51638636702171,0.9478531474732188,-0.022088097488964575,1.4329258820598159,1.1748381597601374,0.9478531474732188,0.14695211780225223,1.212138715175788,0.8709321917690549,-0.10770002139860704,1.5414559276361184,-0.36882191692968064,0.23036622014532987,-0.8179346882917339,0.5964120554641071,0.3949453920319386,0.7150999985878068,0.909473770504105,-0.3248598804887178,0.23036622014532987,-0.36882191692968064,0.8709321917690549,-0.5017540153159744,0.9860724317343753,-0.10770002139860704,0.6361522503407359,-2.6205454294508153,-0.4572697498231123,1.1373892537486945,0.8709321917690549,-0.546410842239735,-0.06480379588709152,0.23036622014532987,-0.4572697498231123,0.31303318522898527,0.5564909583357176,0.5564909583357176,-1.426742025084107,-0.06480379588709152,0.6361522503407359,0.14695211780225223,-0.10770002139860704,0.27179356591045745,0.7933537558921767,0.5564909583357176,-0.546410842239735,-0.5912394888767456,0.3540841185619894,0.020446217421404334,-0.6814093200124656,0.6757140740040977,0.9860724317343753,-0.36882191692968064,-1.1893259001279373,1.0620389315076852,-0.36882191692968064,0.10496721166567786,-0.15077592925131486,0.14695211780225223,0.909473770504105,0.8322262551325478,-0.022088097488964575,0.4356160170646649,-1.0488191777371687,0.6361522503407359,-0.2810734678085235,0.7150999985878068,0.8709321917690549,-0.546410842239735,0.23036622014532987,-2.2128846144553442,0.6361522503407359,2.1351656880009666,-0.06480379588709152,-0.1940306860173823,-0.5017540153159744,0.3949453920319386,-0.8637791771530676,0.31303318522898527,0.18875209347989597,-0.6814093200124656,-0.7267490661171271,-0.4572697498231123,1.7549981936289338,-0.6362392226649662,-0.36882191692968064,-0.9097905400273109 3367 Molecular transducer activity 10 30 2.942770861948625 0.0032528908573212 Q5KU26,Q9BUN8,Q99720,P30536,Q8WTV0,O15118,P11717,Q07954,Q14108,O14786 Functions GO Molecular function msigdb_gomf 66,335,37,290,110,81,53,120,27,127 127,720,81,2899,1105,1309,53,592,290,636,1916,597,2918,120,1855,27,1606,2677,2875,66,1411,110,697,1528,37,335,404,1011,2317,2056 1.5773671103553362,0.4760956266149155,2.032866242545018,-0.7722577547913748,0.23036622014532987,0.10496721166567786,2.664757267155283,0.5964120554641071,1.0241336866990407,0.5564909583357176,-0.1940306860173823,0.5964120554641071,-0.7722577547913748,1.613148049789865,-0.15077592925131486,3.6248188309031892,-0.022088097488964575,-0.5912394888767456,-0.7267490661171271,2.2364769766120918,0.06279828060143189,1.6843250163853651,0.51638636702171,0.020446217421404334,3.201023198065498,0.9478531474732188,0.8322262551325478,0.31303318522898527,-0.36882191692968064,-0.23746346936348223 3367 Regulation of lipid metabolic process 12 53 2.9426437424951923 0.0032542267139317 Q9UBM7,P30536,Q13510,Q8WTV0,Q96N66,Q96G23,P42345,P07602,Q92604,P61916,Q2T9J0,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 1,290,104,110,144,143,107,17,223,25,92,162 1163,2147,3029,1305,1904,3278,2501,1663,2247,2155,2796,17,1172,2991,1992,290,1477,1579,2000,107,2003,1393,1845,1117,25,2090,2813,2268,645,104,1602,1122,2022,419,687,92,3196,690,2758,1204,110,223,2763,143,144,350,3286,162,1,660,1545,2320,2894 0.18875209347989597,-0.3248598804887178,-0.9097905400273109,0.10496721166567786,-0.1940306860173823,-1.4747054833332776,-0.5017540153159744,-0.06480379588709152,-0.36882191692968064,-0.3248598804887178,-0.6814093200124656,4.3750256940936305,0.18875209347989597,-0.8637791771530676,-0.23746346936348223,1.0241336866990407,0.020446217421404334,-0.022088097488964575,-0.23746346936348223,1.6843250163853651,-0.23746346936348223,0.06279828060143189,-0.15077592925131486,0.23036622014532987,3.772633277255873,-0.2810734678085235,-0.6814093200124656,-0.36882191692968064,0.5564909583357176,1.719723884747831,-0.022088097488964575,0.23036622014532987,-0.23746346936348223,0.7933537558921767,0.51638636702171,1.8948765913387664,-1.1893259001279373,0.51638636702171,-0.6362392226649662,0.18875209347989597,1.6843250163853651,1.212138715175788,-0.6362392226649662,1.5054130123499248,1.5054130123499248,0.909473770504105,-1.4747054833332776,1.4329258820598159,6.354521266861696,0.5564909583357176,0.020446217421404334,-0.36882191692968064,-0.7267490661171271 3367 Recurrent respiratory infections 28 131 2.941285719739442 0.0032685289523937 Q07864,Q9Y2Q5,P04066,P15586,Q9Y4I1,P07602,Q15833,P60891,Q9H2P0,P53634,Q9NZJ7,P41229,O00462,P16278,P13051,Q93008,P51798,P54802,P10253,O14617,P02786,Q9NPL8,P01889,Q96HA7,Q13510,P78527,Q12768,P14174 Drugs and Diseases Human Phenotype Ontology msigdb_hp 367,136,6,13,287,17,420,24,426,274,162,33,40,164,163,311,307,54,59,183,67,80,84,349,104,113,121,116 408,40,2573,183,497,3211,3146,1558,1104,1902,1228,2722,2652,2337,1743,1306,2066,2903,1907,1377,1825,84,67,841,6,3193,730,17,1908,1465,59,1667,2342,2990,2343,790,163,116,13,164,1042,671,3240,1473,1109,1233,506,1994,1670,2352,1318,1580,636,33,2513,2996,1320,546,735,599,1325,307,510,1588,274,736,54,1843,2008,24,1846,1245,1765,2089,113,2180,1183,682,2268,1769,367,2524,121,2963,1119,104,1058,1125,3302,2096,2750,420,1191,1609,3246,2753,609,1791,2197,2549,311,2550,2476,1799,349,1353,2301,701,530,1007,1641,426,2308,2976,3082,1361,80,1437,2134,162,1442,3209,1014,710,946,136,2942,1295,287,774,2646 0.7933537558921767,3.1081955602316613,-0.546410842239735,1.3231682601538646,0.6757140740040977,-1.2364869532593843,-1.0954913801193207,-0.022088097488964575,0.23036622014532987,-0.1940306860173823,0.14695211780225223,-0.6362392226649662,-0.5912394888767456,-0.412958796825298,-0.10770002139860704,0.10496721166567786,-0.2810734678085235,-0.7722577547913748,-0.1940306860173823,0.06279828060143189,-0.15077592925131486,1.9985415804284918,2.202814512277326,0.3949453920319386,5.477203395245907,-1.1893259001279373,0.4760956266149155,4.3750256940936305,-0.1940306860173823,0.020446217421404334,2.4362503004565204,-0.06480379588709152,-0.412958796825298,-0.8637791771530676,-0.412958796825298,0.4356160170646649,1.3964785412072227,1.613148049789865,4.896921049154351,1.3964785412072227,0.27179356591045745,0.51638636702171,-1.3312935370263337,0.020446217421404334,0.23036622014532987,0.14695211780225223,0.6757140740040977,-0.23746346936348223,-0.06480379588709152,-0.412958796825298,0.10496721166567786,-0.022088097488964575,0.5564909583357176,3.3236578103542245,-0.5017540153159744,-0.8637791771530676,0.10496721166567786,0.6361522503407359,0.4760956266149155,0.5964120554641071,0.10496721166567786,0.9860724317343753,0.6757140740040977,-0.022088097488964575,1.0620389315076852,0.4760956266149155,2.664757267155283,-0.15077592925131486,-0.23746346936348223,3.8312646321143324,-0.15077592925131486,0.14695211780225223,-0.10770002139860704,-0.2810734678085235,1.6488002071649115,-0.3248598804887178,0.18875209347989597,0.51638636702171,-0.36882191692968064,-0.10770002139860704,0.8709321917690549,-0.5017540153159744,1.613148049789865,-0.8179346882917339,0.23036622014532987,1.719723884747831,0.27179356591045745,0.23036622014532987,-1.6195456688999854,-0.2810734678085235,-0.6362392226649662,0.7933537558921767,0.18875209347989597,-0.022088097488964575,-1.3312935370263337,-0.6362392226649662,0.5964120554641071,-0.10770002139860704,-0.3248598804887178,-0.5017540153159744,0.9860724317343753,-0.5017540153159744,-0.4572697498231123,-0.10770002139860704,0.909473770504105,0.10496721166567786,-0.36882191692968064,0.51638636702171,0.6757140740040977,0.31303318522898527,-0.022088097488964575,0.7933537558921767,-0.36882191692968064,-0.8179346882917339,-0.9559681035265681,0.10496721166567786,2.0670777141599412,0.06279828060143189,-0.2810734678085235,1.4329258820598159,0.06279828060143189,-1.1893259001279373,0.31303318522898527,0.51638636702171,0.3540841185619894,1.5414559276361184,-0.7722577547913748,0.14695211780225223,1.0620389315076852,0.4760956266149155,-0.546410842239735 3367 Carbohydrate derivative transport 6 14 2.9406698160908284 0.0032750342976708 Q8WTV0,P07602,L0R6Q1,P61916,Q9HC21,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 110,17,83,25,192,162 83,1373,788,17,1040,789,2355,25,2606,561,110,225,192,162 1.9985415804284918,0.06279828060143189,0.4356160170646649,4.3750256940936305,0.27179356591045745,0.4356160170646649,-0.412958796825298,3.772633277255873,-0.546410842239735,0.6361522503407359,1.6843250163853651,1.212138715175788,1.3231682601538646,1.4329258820598159 3367 Visual loss 12 50 2.9358764043834285 0.0033260681515105 P48449,O14773,O75503,P50897,Q8TC12,P04439,Q12948,P07602,P01889,P51798,P60891,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 215,2,3,35,172,73,324,17,84,307,24,162 1656,666,337,1451,2,3146,2846,1903,1982,3,724,728,2795,84,3150,73,17,1310,1465,732,672,1914,2082,2354,215,35,2363,307,2005,849,24,978,1772,2524,2963,324,1120,1334,3158,1864,2610,172,3364,2550,1278,1280,1714,1719,1966,162 -0.06480379588709152,0.51638636702171,0.909473770504105,0.020446217421404334,5.884770299255648,-1.0954913801193207,-0.7267490661171271,-0.1940306860173823,-0.23746346936348223,5.682423722639393,0.4760956266149155,0.4760956266149155,-0.6814093200124656,1.9985415804284918,-1.0954913801193207,2.1011771507196184,4.3750256940936305,0.10496721166567786,0.020446217421404334,0.4760956266149155,0.51638636702171,-0.1940306860173823,-0.2810734678085235,-0.412958796825298,1.212138715175788,3.2625005214835268,-0.412958796825298,0.9860724317343753,-0.23746346936348223,0.3949453920319386,3.8312646321143324,0.31303318522898527,-0.10770002139860704,-0.5017540153159744,-0.8179346882917339,0.9478531474732188,0.23036622014532987,0.10496721166567786,-1.0954913801193207,-0.15077592925131486,-0.546410842239735,1.3964785412072227,-5.962712518670952,-0.5017540153159744,0.14695211780225223,0.14695211780225223,-0.06480379588709152,-0.06480379588709152,-0.1940306860173823,1.4329258820598159 3367 Peptide binding 10 71 2.9097685555348995 0.0036169649326645 Q15392,Q9UIQ6,O14773,P04439,P55899,Q8WTV0,P42892,P01889,Q07954,Q13427 Functions GO Molecular function msigdb_gomf 0,32,2,73,43,110,16,84,120,122 2648,2944,894,1162,2,1558,1662,1105,1030,3033,84,73,2071,412,1039,213,542,1473,3241,673,2800,2950,1112,1317,2737,734,1836,16,1583,3228,1051,1322,2998,3300,1587,1844,43,1846,679,2917,1595,2962,120,2744,2816,2184,122,2526,2528,1335,0,2824,423,110,1709,1520,564,1355,759,3017,1640,426,3142,161,944,1724,3344,32,1367,772,2897 -0.5912394888767456,-0.8179346882917339,0.3540841185619894,0.18875209347989597,5.884770299255648,-0.022088097488964575,-0.06480379588709152,0.23036622014532987,0.27179356591045745,-0.9097905400273109,1.9985415804284918,2.1011771507196184,-0.2810734678085235,0.7933537558921767,0.27179356591045745,1.212138715175788,0.6361522503407359,0.020446217421404334,-1.3312935370263337,0.51638636702171,-0.6814093200124656,-0.8179346882917339,0.23036622014532987,0.10496721166567786,-0.6362392226649662,0.4760956266149155,-0.15077592925131486,4.4588127644301565,-0.022088097488964575,-1.2838097038521317,0.27179356591045745,0.10496721166567786,-0.8637791771530676,-1.6195456688999854,-0.022088097488964575,-0.15077592925131486,3.0458947300580568,-0.15077592925131486,0.51638636702171,-0.7722577547913748,-0.022088097488964575,-0.8179346882917339,1.613148049789865,-0.6362392226649662,-0.6814093200124656,-0.3248598804887178,1.613148049789865,-0.5017540153159744,-0.5017540153159744,0.10496721166567786,9.266342596549883,-0.6814093200124656,0.7933537558921767,1.6843250163853651,-0.06480379588709152,0.020446217421404334,0.6361522503407359,0.10496721166567786,0.4760956266149155,-0.8637791771530676,-0.022088097488964575,0.7933537558921767,-1.0488191777371687,1.4329258820598159,0.3540841185619894,-0.06480379588709152,-2.3646418191340213,3.354118052447859,0.10496721166567786,0.4760956266149155,-0.7267490661171271 3367 Organic hydroxy compound metabolic process 14 116 2.8960238031432084 0.0037792373284886 Q15392,Q9UBM7,P80404,Q14739,Q15125,Q13510,Q8WTV0,Q6NUM9,P05067,O15118,Q99538,Q16850,P61916,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,65,38,7,104,110,76,14,81,20,157,25,30 2420,1096,1821,1298,81,1025,1659,1977,2241,2335,2651,1984,3278,2501,3122,1985,2581,2070,787,841,2582,14,729,2504,3174,1570,1572,1909,2731,1989,1990,2991,1174,1175,1752,1110,2993,1832,258,2258,1475,3363,1579,1388,361,30,1389,2168,3069,2515,215,3257,2003,3258,1482,1325,2596,1114,1762,2807,850,1240,852,25,65,1686,1934,3339,1183,1185,1772,645,104,3231,1122,1252,1857,38,370,329,2922,7,3075,0,607,2024,446,2820,157,76,333,878,172,110,2763,2477,1074,758,2480,20,1714,2400,2887,2705,571,1358,2312,1435,1086,1,831,2713,832,1093,3354,3027 -0.4572697498231123,0.23036622014532987,-0.15077592925131486,0.10496721166567786,2.032866242545018,0.27179356591045745,-0.06480379588709152,-0.23746346936348223,-0.36882191692968064,-0.412958796825298,-0.5912394888767456,-0.23746346936348223,-1.4747054833332776,-0.5017540153159744,-1.0488191777371687,-0.23746346936348223,-0.546410842239735,-0.2810734678085235,0.4356160170646649,0.3949453920319386,-0.546410842239735,4.815860976496678,0.4760956266149155,-0.5017540153159744,-1.142327166182432,-0.022088097488964575,-0.022088097488964575,-0.1940306860173823,-0.6362392226649662,-0.23746346936348223,-0.23746346936348223,-0.8637791771530676,0.18875209347989597,0.18875209347989597,-0.10770002139860704,0.23036622014532987,-0.8637791771530676,-0.15077592925131486,1.099790142352336,-0.36882191692968064,0.020446217421404334,-5.256126429676467,-0.022088097488964575,0.06279828060143189,0.8709321917690549,3.4751842548839553,0.06279828060143189,-0.3248598804887178,-0.9559681035265681,-0.5017540153159744,1.212138715175788,-1.378937844623164,-0.23746346936348223,-1.378937844623164,0.020446217421404334,0.10496721166567786,-0.546410842239735,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,0.3949453920319386,0.14695211780225223,0.3949453920319386,3.772633277255873,2.2364769766120918,-0.06480379588709152,-0.1940306860173823,-2.3139063625418146,0.18875209347989597,0.18875209347989597,-0.10770002139860704,0.5564909583357176,1.719723884747831,-1.2838097038521317,0.23036622014532987,0.14695211780225223,-0.15077592925131486,3.1701628794451158,0.8709321917690549,0.9478531474732188,-0.7722577547913748,5.347423495313898,-0.9559681035265681,9.266342596549883,0.5964120554641071,-0.23746346936348223,0.754312439228042,-0.6814093200124656,1.4329258820598159,2.0670777141599412,0.9478531474732188,0.3949453920319386,1.3964785412072227,1.6843250163853651,-0.6362392226649662,-0.4572697498231123,0.27179356591045745,0.4760956266149155,-0.4572697498231123,3.9186948792031995,-0.06480379588709152,-0.412958796825298,-0.7267490661171271,-0.5912394888767456,0.6361522503407359,0.10496721166567786,-0.36882191692968064,0.06279828060143189,0.27179356591045745,6.354521266861696,0.4356160170646649,-0.5912394888767456,0.4356160170646649,0.27179356591045745,-2.6721680762670923,-0.8637791771530676 3367 Vacuole organization 9 54 2.8875349141300286 0.0038827351160297 O14773,P50897,O75503,P07686,P11117,P10253,P42345,P54802,Q14108 Processes and pathways GO Biological process msigdb_gobp 2,35,3,103,41,59,107,54,27 408,2,2149,3,1744,1565,2793,841,2986,103,59,41,1173,2436,107,735,35,908,3306,54,2809,1243,2522,121,27,1779,2189,1944,690,3104,1346,421,1204,2390,2476,2765,3109,1074,2830,1889,2403,1641,572,453,2219,2226,2981,3116,3170,3337,1016,3335,2717,663 0.7933537558921767,5.884770299255648,-0.3248598804887178,5.682423722639393,-0.10770002139860704,-0.022088097488964575,-0.6814093200124656,0.3949453920319386,-0.8637791771530676,1.719723884747831,2.4362503004565204,3.077087184000687,0.18875209347989597,-0.4572697498231123,1.6843250163853651,0.4760956266149155,3.2625005214835268,0.3540841185619894,-1.6681404132370228,2.664757267155283,-0.6814093200124656,0.14695211780225223,-0.5017540153159744,1.613148049789865,3.6248188309031892,-0.10770002139860704,-0.3248598804887178,-0.1940306860173823,0.51638636702171,-1.0023112020703986,0.10496721166567786,0.7933537558921767,0.18875209347989597,-0.412958796825298,-0.4572697498231123,-0.6362392226649662,-1.0023112020703986,0.27179356591045745,-0.6814093200124656,-0.15077592925131486,-0.412958796825298,-0.022088097488964575,0.6361522503407359,0.754312439228042,-0.3248598804887178,-0.3248598804887178,-0.8179346882917339,-1.0023112020703986,-1.0954913801193207,-2.2633204624512464,0.31303318522898527,-2.1625993189318375,-0.5912394888767456,0.5564909583357176 3367 Cargo receptor activity 6 8 2.87533112994803 0.0040360397777505 Q5KU26,P02786,Q08380,Q8WTV0,O15260,Q14108 Functions GO Molecular function msigdb_gomf 66,67,11,110,49,27 49,67,120,11,27,2534,66,110 2.793240616952005,2.202814512277326,1.613148049789865,5.137248975932357,3.6248188309031892,-0.5017540153159744,2.2364769766120918,1.6843250163853651 3367 Glycolipid binding 6 9 2.870266410073093 0.0041012609485668 P55145,O14773,P50897,Q9UM22,P07602,Q9NZJ7 Functions GO Molecular function msigdb_gomf 154,2,35,8,17,162 2,17,35,1842,154,1955,284,162,8 5.884770299255648,4.3750256940936305,3.2625005214835268,-0.15077592925131486,1.4329258820598159,-0.1940306860173823,1.0620389315076852,1.4329258820598159,5.347423495313898 3367 Oxidoreductase activity acting on the ch ch group of donors 8 26 2.865648424906048 0.0041615613626708 Q15392,Q9UBM7,Q14739,Q8N4Q0,Q6NUM9,P30043,P11310,Q14914 Functions GO Molecular function msigdb_gomf 0,1,38,12,76,228,91,329 1101,3174,91,2349,2859,228,847,1999,3152,597,2003,2173,38,329,2674,0,76,12,3320,2202,2551,3142,2777,2221,336,1 0.23036622014532987,-1.142327166182432,1.8948765913387664,-0.412958796825298,-0.7267490661171271,1.1748381597601374,0.3949453920319386,-0.23746346936348223,-1.0954913801193207,0.5964120554641071,-0.23746346936348223,-0.3248598804887178,3.1701628794451158,0.9478531474732188,-0.5912394888767456,9.266342596549883,2.0670777141599412,5.110752473018885,-1.8148607923698326,-0.3248598804887178,-0.5017540153159744,-1.0488191777371687,-0.6362392226649662,-0.3248598804887178,0.9478531474732188,6.354521266861696 3367 Other glycan degradation 6 8 2.852234706027701 0.0043413033192947 Q9BTY2,P04066,P07686,O00462,O00754,P06865 Processes and pathways KEGG Pathways msigdb_kegg 4,6,103,40,44,47 40,44,841,6,47,103,164,4 3.1081955602316613,3.014617485988229,0.3949453920319386,5.477203395245907,2.9518057266228475,1.719723884747831,1.3964785412072227,5.6569309364282425 3367 Parkinsonism 8 32 2.851220479701725 0.0043551759124944 Q709C8,Q99720,Q13501,P05067,P07602,Q9NZJ7,O75165,O96008 Drugs and Diseases Human Phenotype Ontology msigdb_hp 200,37,234,14,17,162,300,271 300,2948,271,841,14,17,439,2162,1478,1319,1325,2262,852,515,2182,1687,1490,234,1604,330,919,200,1074,816,1075,2480,37,162,2894,950,2717,2493 0.9860724317343753,-0.8179346882917339,1.0620389315076852,0.3949453920319386,4.815860976496678,4.3750256940936305,0.754312439228042,-0.3248598804887178,0.020446217421404334,0.10496721166567786,0.10496721166567786,-0.36882191692968064,0.3949453920319386,0.6757140740040977,-0.3248598804887178,-0.06480379588709152,0.020446217421404334,1.1748381597601374,-0.022088097488964575,0.9478531474732188,0.3540841185619894,1.2863020037686608,0.27179356591045745,0.4356160170646649,0.27179356591045745,-0.4572697498231123,3.201023198065498,1.4329258820598159,-0.7267490661171271,0.3540841185619894,-0.5912394888767456,-0.4572697498231123 3367 Abnormal exteroceptive sensation 8 58 2.8491254065532785 0.0043839596568233 P41229,P07686,P05067,P07602,P01889,P54802,P06280,P60891 Drugs and Diseases Human Phenotype Ontology msigdb_hp 33,103,14,17,84,54,23,24 337,1025,1659,3146,1900,2337,2068,84,2582,3269,14,1378,23,17,103,2853,466,439,2907,2800,1474,847,469,33,1839,1919,3178,597,1325,548,1841,2366,54,1589,2262,851,24,2599,1934,2962,2091,2182,2524,1774,1406,2531,2923,2106,1343,1203,485,2301,2936,1721,944,162,3056,2141 0.909473770504105,0.27179356591045745,-0.06480379588709152,-1.0954913801193207,-0.1940306860173823,-0.412958796825298,-0.2810734678085235,1.9985415804284918,-0.546410842239735,-1.426742025084107,4.815860976496678,0.06279828060143189,3.860476447122193,4.3750256940936305,1.719723884747831,-0.7267490661171271,0.7150999985878068,0.754312439228042,-0.7722577547913748,-0.6814093200124656,0.020446217421404334,0.3949453920319386,0.7150999985878068,3.3236578103542245,-0.15077592925131486,-0.1940306860173823,-1.142327166182432,0.5964120554641071,0.10496721166567786,0.6361522503407359,-0.15077592925131486,-0.412958796825298,2.664757267155283,-0.022088097488964575,-0.36882191692968064,0.3949453920319386,3.8312646321143324,-0.546410842239735,-0.1940306860173823,-0.8179346882917339,-0.2810734678085235,-0.3248598804887178,-0.5017540153159744,-0.10770002139860704,0.06279828060143189,-0.5017540153159744,-0.7722577547913748,-0.2810734678085235,0.10496721166567786,0.18875209347989597,0.7150999985878068,-0.36882191692968064,-0.7722577547913748,-0.06480379588709152,0.3540841185619894,1.4329258820598159,-0.9097905400273109,-0.2810734678085235 3367 Circulatory system process 20 70 2.83555953547318 0.0045745487954844 Q9HB40,P30825,P42892,P42785,Q9UIQ6,P53985,P48507,P10253,O14745,P80404,P02786,O94813,Q99996,Q12948,Q99808,Q16625,P11166,P42345,O00443,Q07954 Processes and pathways GO Biological process msigdb_gobp 9,259,16,31,32,294,417,59,433,65,67,194,79,324,225,476,466,107,357,120 1451,357,433,960,2425,2244,1904,2902,1564,194,2070,67,464,900,2796,3340,1908,59,466,2990,1909,2798,2588,1173,2435,1109,2950,1578,259,2355,2513,107,31,16,1584,1320,417,1052,1325,294,2916,1117,2450,3271,65,683,1249,120,2866,324,1402,744,745,1778,2096,2677,476,1696,3046,874,2761,1636,225,79,2936,9,2217,944,32,3172 0.020446217421404334,0.8709321917690549,0.754312439228042,0.31303318522898527,-0.4572697498231123,-0.36882191692968064,-0.1940306860173823,-0.7722577547913748,-0.022088097488964575,1.2863020037686608,-0.2810734678085235,2.202814512277326,0.7150999985878068,0.3540841185619894,-0.6814093200124656,-2.3646418191340213,-0.1940306860173823,2.4362503004565204,0.7150999985878068,-0.8637791771530676,-0.1940306860173823,-0.6814093200124656,-0.546410842239735,0.18875209347989597,-0.4572697498231123,0.23036622014532987,-0.8179346882917339,-0.022088097488964575,1.099790142352336,-0.412958796825298,-0.5017540153159744,1.6843250163853651,3.4450326941058216,4.4588127644301565,-0.022088097488964575,0.10496721166567786,0.7933537558921767,0.27179356591045745,0.10496721166567786,1.0241336866990407,-0.7722577547913748,0.23036622014532987,-0.4572697498231123,-1.426742025084107,2.2364769766120918,0.51638636702171,0.14695211780225223,1.613148049789865,-0.7267490661171271,0.9478531474732188,0.06279828060143189,0.4760956266149155,0.4760956266149155,-0.10770002139860704,-0.2810734678085235,-0.5912394888767456,0.7150999985878068,-0.06480379588709152,-0.9097905400273109,0.3949453920319386,-0.6362392226649662,-0.022088097488964575,1.212138715175788,2.0670777141599412,-0.7722577547913748,5.321323717121585,-0.3248598804887178,0.3540841185619894,3.354118052447859,-1.0954913801193207 3367 Organic hydroxy compound biosynthetic process 8 58 2.8310999394357985 0.0046388224125339 Q15392,Q9UBM7,P48449,Q14739,Q15125,Q13510,Q16850,P37268 Processes and pathways GO Biological process msigdb_gobp 0,1,215,38,7,104,157,30 2420,1096,1821,1298,1025,1659,1977,2501,2581,2070,841,729,1570,1572,2731,2991,1175,1110,2993,258,2258,1475,1388,30,3069,215,1114,1762,2807,852,3339,1185,645,104,1252,1857,38,7,3075,0,2024,446,2820,157,2763,1074,758,2480,1714,571,1358,2312,1086,1,2713,832,3354,3027 -0.4572697498231123,0.23036622014532987,-0.15077592925131486,0.10496721166567786,0.27179356591045745,-0.06480379588709152,-0.23746346936348223,-0.5017540153159744,-0.546410842239735,-0.2810734678085235,0.3949453920319386,0.4760956266149155,-0.022088097488964575,-0.022088097488964575,-0.6362392226649662,-0.8637791771530676,0.18875209347989597,0.23036622014532987,-0.8637791771530676,1.099790142352336,-0.36882191692968064,0.020446217421404334,0.06279828060143189,3.4751842548839553,-0.9559681035265681,1.212138715175788,0.23036622014532987,-0.10770002139860704,-0.6814093200124656,0.3949453920319386,-2.3139063625418146,0.18875209347989597,0.5564909583357176,1.719723884747831,0.14695211780225223,-0.15077592925131486,3.1701628794451158,5.347423495313898,-0.9559681035265681,9.266342596549883,-0.23746346936348223,0.754312439228042,-0.6814093200124656,1.4329258820598159,-0.6362392226649662,0.27179356591045745,0.4760956266149155,-0.4572697498231123,-0.06480379588709152,0.6361522503407359,0.10496721166567786,-0.36882191692968064,0.27179356591045745,6.354521266861696,-0.5912394888767456,0.4356160170646649,-2.6721680762670923,-0.8637791771530676 3367 Isoprenoid metabolic process 7 22 2.828316236449109 0.0046793557307653 Q07954,P29375,Q8TC12,Q9HB40,Q6NUM9,P61916,P37268 Processes and pathways GO Biological process msigdb_gobp 120,69,172,9,76,25,30 2147,2651,1909,2731,1990,69,30,215,2596,1762,25,3339,1185,120,1252,3075,1194,76,878,172,9,1093 -0.3248598804887178,-0.5912394888767456,-0.1940306860173823,-0.6362392226649662,-0.23746346936348223,2.1690444425785262,3.4751842548839553,1.212138715175788,-0.546410842239735,-0.10770002139860704,3.772633277255873,-2.3139063625418146,0.18875209347989597,1.613148049789865,0.14695211780225223,-0.9559681035265681,0.18875209347989597,2.0670777141599412,0.3949453920319386,1.3964785412072227,5.321323717121585,0.27179356591045745 3367 Cysteine protease 12 46 2.8282995419170813 0.0046795997830322 Q9UPT9,Q01804,Q66K14,Q13510,P42574,Q92820,Q8NHP8,Q70CQ2,P08243,P61247,Q99538,P53634 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 205,71,375,104,260,77,15,280,208,229,20,274 1456,1032,2586,208,1992,1313,1832,1044,260,1917,2739,2170,2448,274,2663,229,71,3073,1599,104,392,2672,1501,1503,2382,375,989,280,15,2198,1955,77,1877,2973,1632,2479,2480,20,704,1894,3209,205,2139,717,663,2644 0.020446217421404334,0.27179356591045745,-0.546410842239735,1.249292736644776,-0.23746346936348223,0.10496721166567786,-0.15077592925131486,0.27179356591045745,1.099790142352336,-0.1940306860173823,-0.6362392226649662,-0.3248598804887178,-0.4572697498231123,1.0620389315076852,-0.5912394888767456,1.1748381597601374,2.1351656880009666,-0.9559681035265681,-0.022088097488964575,1.719723884747831,0.8322262551325478,-0.5912394888767456,0.020446217421404334,0.020446217421404334,-0.412958796825298,0.8709321917690549,0.31303318522898527,1.0620389315076852,4.815860976496678,-0.3248598804887178,-0.1940306860173823,2.0670777141599412,-0.15077592925131486,-0.8179346882917339,-0.022088097488964575,-0.4572697498231123,-0.4572697498231123,3.9186948792031995,0.51638636702171,-0.15077592925131486,-1.1893259001279373,1.2863020037686608,-0.2810734678085235,0.51638636702171,0.5564909583357176,-0.546410842239735 3367 Abnormal shape of the frontal region 22 117 2.823605731987175 0.0047486760208637 Q15392,P04066,Q15125,O14646,P15586,Q14739,P16278,O00754,Q8NCM8,Q00839,P51798,Q96HA7,O75970,P19022,Q86V48,O00170,Q6PGP7,P42345,Q9H9Y6,Q12768,Q2M1P5,O75962 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,6,7,132,13,38,164,44,181,179,307,349,340,214,98,337,377,107,383,121,371,358 337,44,132,497,2984,1822,3211,2331,2719,1226,2064,2788,1902,1167,1980,358,340,727,1743,1462,1377,6,1037,2727,2987,1231,1573,13,164,2991,732,214,2907,1176,2348,1109,2949,1754,2076,2910,2165,3066,2000,636,3128,107,1839,415,793,2363,307,3352,1589,1930,2742,2450,1683,2180,179,1183,2452,742,2182,367,121,1774,1119,1120,2457,38,2674,7,1692,0,1497,1188,2750,1189,1609,371,2604,3246,2924,2753,377,1343,98,1950,523,811,181,560,562,1205,1799,349,1353,927,996,2207,701,821,2308,383,765,2633,2410,1441,3022,623,1015,1727,624,2490,3192,1295,2646 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3367 Rac1 gtpase cycle 15 48 2.822198653492637 0.0047695622838919 Q7L576,Q96HP0,P02786,O75962,Q14185,Q14739,Q13459,Q13576,Q96F07,P46940,Q9Y2I1,P63167,Q86VI3,Q9UQB8,P43121 Processes and pathways Reactome Pathways msigdb_reactome 263,253,67,358,101,38,262,235,111,246,126,277,222,29,342 1369,626,459,358,67,1309,2990,2001,2803,342,246,1840,908,2959,1117,1245,277,2523,2271,2375,262,235,101,1778,38,2677,1189,1063,396,690,263,750,222,2761,111,253,1279,3185,2626,1079,1810,2217,1537,29,661,126,3192,951 0.06279828060143189,0.5564909583357176,0.7150999985878068,0.8709321917690549,2.202814512277326,0.10496721166567786,-0.8637791771530676,-0.23746346936348223,-0.6814093200124656,0.909473770504105,1.1373892537486945,-0.15077592925131486,0.3540841185619894,-0.8179346882917339,0.23036622014532987,0.14695211780225223,1.0620389315076852,-0.5017540153159744,-0.36882191692968064,-0.412958796825298,1.099790142352336,1.1748381597601374,1.7549981936289338,-0.10770002139860704,3.1701628794451158,-0.5912394888767456,0.18875209347989597,0.27179356591045745,0.8322262551325478,0.51638636702171,1.099790142352336,0.4760956266149155,1.212138715175788,-0.6362392226649662,1.6843250163853651,1.1373892537486945,0.14695211780225223,-1.142327166182432,-0.546410842239735,0.27179356591045745,-0.10770002139860704,-0.3248598804887178,0.020446217421404334,3.535260987655072,0.5564909583357176,1.613148049789865,-1.142327166182432,0.3540841185619894 3367 Contractures of the joints of the upper limbs 7 80 2.817085723390832 0.0048461589158785 Q15392,P41229,O43933,Q99720,Q8IZA0,P42892,P37268 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,33,96,37,39,16,30 3089,357,1225,497,2787,2576,96,585,960,2721,1031,1904,2501,727,3148,730,2990,2991,1042,1109,1993,2437,195,1670,2165,1319,30,3128,33,16,2996,793,1840,1325,1589,1327,2520,1183,682,1334,1251,1123,1406,1690,2529,1779,0,2753,691,2755,1864,609,1342,98,39,1794,1624,1270,281,995,2038,927,996,2207,2702,37,1142,2209,2629,1534,2483,2836,1721,889,3116,948,2982,1730,949,2141 -1.0023112020703986,0.8709321917690549,0.14695211780225223,0.6757140740040977,-0.6814093200124656,-0.546410842239735,1.8251785328251016,0.5964120554641071,0.31303318522898527,-0.6362392226649662,0.27179356591045745,-0.1940306860173823,-0.5017540153159744,0.4760956266149155,-1.0954913801193207,0.4760956266149155,-0.8637791771530676,-0.8637791771530676,0.27179356591045745,0.23036622014532987,-0.23746346936348223,-0.4572697498231123,1.2863020037686608,-0.06480379588709152,-0.3248598804887178,0.10496721166567786,3.4751842548839553,-1.0488191777371687,3.3236578103542245,4.4588127644301565,-0.8637791771530676,0.4356160170646649,-0.15077592925131486,0.10496721166567786,-0.022088097488964575,0.10496721166567786,-0.5017540153159744,0.18875209347989597,0.51638636702171,0.10496721166567786,0.14695211780225223,0.23036622014532987,0.06279828060143189,-0.06480379588709152,-0.5017540153159744,-0.10770002139860704,9.266342596549883,-0.6362392226649662,0.51638636702171,-0.6362392226649662,-0.15077592925131486,0.5964120554641071,0.10496721166567786,1.790149299150869,3.13922056117222,-0.10770002139860704,-0.022088097488964575,0.14695211780225223,1.0620389315076852,0.31303318522898527,-0.23746346936348223,0.3540841185619894,0.31303318522898527,-0.3248598804887178,-0.5912394888767456,3.201023198065498,0.23036622014532987,-0.3248598804887178,-0.546410842239735,0.020446217421404334,-0.4572697498231123,-0.6814093200124656,-0.06480379588709152,0.3949453920319386,-1.0023112020703986,0.3540841185619894,-0.8179346882917339,-0.06480379588709152,0.3540841185619894,-0.2810734678085235 3367 Abnormality of the gingiva 15 50 2.814889949985785 0.0048793939945062 Q15392,Q9UBM7,Q9H7D7,O00203,Q14739,P16278,Q13155,O00754,P49257,Q93008,P49815,Q2M1P5,Q9BUR4,Q14108,P53634 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,1,268,408,38,164,325,44,509,311,546,371,530,27,274 3089,408,44,1104,1228,1565,2903,841,3193,1748,2588,164,3240,2348,1580,636,1049,509,546,274,1846,2089,1183,1184,2524,325,2376,27,38,606,3302,0,371,2534,2753,1409,3248,1864,2542,311,1278,2041,530,268,1361,2134,1,710,2642,774 -1.0023112020703986,0.7933537558921767,3.014617485988229,0.23036622014532987,0.14695211780225223,-0.022088097488964575,-0.7722577547913748,0.3949453920319386,-1.1893259001279373,-0.10770002139860704,-0.546410842239735,1.3964785412072227,-1.3312935370263337,-0.412958796825298,-0.022088097488964575,0.5564909583357176,0.27179356591045745,0.6757140740040977,0.6361522503407359,1.0620389315076852,-0.15077592925131486,-0.2810734678085235,0.18875209347989597,0.18875209347989597,-0.5017540153159744,0.9478531474732188,-0.412958796825298,3.6248188309031892,3.1701628794451158,0.5964120554641071,-1.6195456688999854,9.266342596549883,0.8709321917690549,-0.5017540153159744,-0.6362392226649662,0.06279828060143189,-1.3312935370263337,-0.15077592925131486,-0.5017540153159744,0.9860724317343753,0.14695211780225223,-0.23746346936348223,0.6757140740040977,1.099790142352336,0.10496721166567786,-0.2810734678085235,6.354521266861696,0.51638636702171,-0.546410842239735,0.4760956266149155 3367 Abnormality of the biliary system 13 124 2.8147307567315107 0.0048818115306323 O43933,Q9UBM7,P41229,P04066,Q14739,Q13510,Q15904,P07602,O15118,P60891,P61916,Q14108,P14174 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,1,33,6,38,104,48,17,81,24,25,27,116 1656,458,1974,81,1301,1104,96,2985,725,3173,1743,1377,2581,3148,841,6,1463,2582,1169,2157,17,2727,1569,1908,1748,466,1231,1572,790,2905,116,413,732,2907,1473,1752,258,1580,3039,1999,1581,2738,2954,2000,2168,2354,33,1582,3315,343,1320,2003,1482,1325,2363,2173,2007,2175,2176,1930,1590,973,1240,24,25,2089,1685,552,978,1771,1772,1600,1119,2376,104,27,38,3302,1860,420,48,1407,476,2104,1262,868,2924,2822,377,609,3047,920,2471,1625,2548,1205,1273,311,2930,649,1353,996,1527,2629,2211,3141,2308,1717,3165,2563,162,1,710,2567,946,889,3170,2490,1160,2942,2232,774,2897,837 -0.06480379588709152,0.7150999985878068,-0.23746346936348223,2.032866242545018,0.10496721166567786,0.23036622014532987,1.8251785328251016,-0.8637791771530676,0.4760956266149155,-1.142327166182432,-0.10770002139860704,0.06279828060143189,-0.546410842239735,-1.0954913801193207,0.3949453920319386,5.477203395245907,0.020446217421404334,-0.546410842239735,0.18875209347989597,-0.3248598804887178,4.3750256940936305,-0.6362392226649662,-0.022088097488964575,-0.1940306860173823,-0.10770002139860704,0.7150999985878068,0.14695211780225223,-0.022088097488964575,0.4356160170646649,-0.7722577547913748,1.613148049789865,0.7933537558921767,0.4760956266149155,-0.7722577547913748,0.020446217421404334,-0.10770002139860704,1.099790142352336,-0.022088097488964575,-0.9097905400273109,-0.23746346936348223,-0.022088097488964575,-0.6362392226649662,-0.8179346882917339,-0.23746346936348223,-0.3248598804887178,-0.412958796825298,3.3236578103542245,-0.022088097488964575,-1.7657985305992057,0.909473770504105,0.10496721166567786,-0.23746346936348223,0.020446217421404334,0.10496721166567786,-0.412958796825298,-0.3248598804887178,-0.23746346936348223,-0.3248598804887178,-0.3248598804887178,-0.1940306860173823,-0.022088097488964575,0.31303318522898527,0.14695211780225223,3.8312646321143324,3.772633277255873,-0.2810734678085235,-0.06480379588709152,0.6361522503407359,0.31303318522898527,-0.10770002139860704,-0.10770002139860704,-0.022088097488964575,0.23036622014532987,-0.412958796825298,1.719723884747831,3.6248188309031892,3.1701628794451158,-1.6195456688999854,-0.15077592925131486,0.7933537558921767,2.888645998928826,0.06279828060143189,0.7150999985878068,-0.2810734678085235,0.14695211780225223,0.3949453920319386,-0.7722577547913748,-0.6814093200124656,0.8709321917690549,0.5964120554641071,-0.9097905400273109,0.3540841185619894,-0.4572697498231123,-0.022088097488964575,-0.5017540153159744,0.18875209347989597,0.14695211780225223,0.9860724317343753,-0.7722577547913748,0.5564909583357176,0.10496721166567786,0.31303318522898527,0.020446217421404334,-0.546410842239735,-0.3248598804887178,-1.0488191777371687,-0.36882191692968064,-0.06480379588709152,-1.0954913801193207,-0.5017540153159744,1.4329258820598159,6.354521266861696,0.51638636702171,-0.5017540153159744,0.3540841185619894,0.3949453920319386,-1.0954913801193207,-0.4572697498231123,0.23036622014532987,-0.7722577547913748,-0.3248598804887178,0.4760956266149155,-0.7267490661171271,0.4356160170646649 3367 Rna phosphodiester bond hydrolysis endonucleolytic 12 37 2.8137253483174622 0.0048971048836863 Q9BSV6,Q99575,Q9ULX3,Q86U38,Q5SY16,Q8N2A8,P78345,O75691,O00584,P27695,Q14692,Q96DE0 Processes and pathways GO Biological process msigdb_gobp 334,266,72,378,308,142,322,207,18,304,346,28 18,1557,207,3173,587,667,540,304,1180,909,681,322,1596,2269,860,346,1336,372,308,1129,2687,378,1267,142,2616,28,1798,266,1282,1529,334,2414,1897,72,1015,3233,3026 4.120355977593298,-0.022088097488964575,1.249292736644776,-1.142327166182432,0.5964120554641071,0.51638636702171,0.6361522503407359,0.9860724317343753,0.18875209347989597,0.3540841185619894,0.51638636702171,0.9478531474732188,-0.022088097488964575,-0.36882191692968064,0.3949453920319386,0.909473770504105,0.10496721166567786,0.8709321917690549,0.9860724317343753,0.23036622014532987,-0.5912394888767456,0.8709321917690549,0.14695211780225223,1.5054130123499248,-0.546410842239735,3.535260987655072,-0.10770002139860704,1.099790142352336,0.14695211780225223,0.020446217421404334,0.9478531474732188,-0.412958796825298,-0.15077592925131486,2.1351656880009666,0.31303318522898527,-1.2838097038521317,-0.8637791771530676 3367 Intrinsic component of endoplasmic reticulum membrane 17 48 2.811125407982956 0.0049368539405911 Q8TB61,Q9UBM7,Q9NZ01,Q9P035,Q9BUN8,P10321,Q15125,Q5J8M3,P04439,Q9NQC3,P61619,Q9H490,P01889,Q15041,Q86UP2,O95470,Q9HCU5 Localization GO Cellular component msigdb_gocc 561,1,336,767,335,213,7,170,73,384,679,284,84,519,750,668,764 1898,954,1298,1558,1904,2792,668,84,73,213,2800,846,2735,2086,1053,679,1935,2378,861,519,7,1606,170,1786,750,3011,1951,2542,561,1954,1955,1517,2930,2041,1528,2626,335,284,764,384,1647,336,767,1011,1,1445,774,1224 -0.1940306860173823,0.31303318522898527,0.10496721166567786,-0.022088097488964575,-0.1940306860173823,-0.6814093200124656,0.51638636702171,1.9985415804284918,2.1011771507196184,1.212138715175788,-0.6814093200124656,0.3949453920319386,-0.6362392226649662,-0.2810734678085235,0.27179356591045745,0.51638636702171,-0.1940306860173823,-0.412958796825298,0.3949453920319386,0.6757140740040977,5.347423495313898,-0.022088097488964575,1.3964785412072227,-0.10770002139860704,0.4760956266149155,-0.8637791771530676,-0.1940306860173823,-0.5017540153159744,0.6361522503407359,-0.1940306860173823,-0.1940306860173823,0.020446217421404334,-0.7722577547913748,-0.23746346936348223,0.020446217421404334,-0.546410842239735,0.9478531474732188,1.0620389315076852,0.4760956266149155,0.8709321917690549,-0.022088097488964575,0.9478531474732188,0.4760956266149155,0.31303318522898527,6.354521266861696,0.06279828060143189,0.4760956266149155,0.18875209347989597 3367 Exogenous protein binding 6 14 2.7982488468671085 0.0051380510580056 P02786,Q8WTV0,O15118,P35613,P11279,Q14108 Functions GO Molecular function msigdb_gomf 67,110,81,305,90,27 81,67,1309,1826,2159,1466,90,542,305,27,327,2677,110,775 2.032866242545018,2.202814512277326,0.10496721166567786,-0.15077592925131486,-0.3248598804887178,0.020446217421404334,1.8948765913387664,0.6361522503407359,0.9860724317343753,3.6248188309031892,0.9478531474732188,-0.5912394888767456,1.6843250163853651,0.4760956266149155 3367 Host cell receptor for virus entry 6 14 2.7982488468671085 0.0051380510580056 P02786,Q8WTV0,O15118,P35613,P11279,Q14108 Functions Protein Atlas Molecular function protein_atlas_molecular_function 67,110,81,305,90,27 81,67,1309,1826,2159,1466,90,542,305,27,327,2677,110,775 2.032866242545018,2.202814512277326,0.10496721166567786,-0.15077592925131486,-0.3248598804887178,0.020446217421404334,1.8948765913387664,0.6361522503407359,0.9860724317343753,3.6248188309031892,0.9478531474732188,-0.5912394888767456,1.6843250163853651,0.4760956266149155 3367 Vascular process in circulatory system 14 32 2.790927514493841 0.005255724096109 P02786,P53985,Q9HB40,P30825,O94813,P42892,P48507,Q12948,Q99808,O00443,Q07954,O14745,Q16625,P11166 Processes and pathways GO Biological process msigdb_gobp 67,294,9,259,194,16,417,324,225,357,120,433,476,466 357,433,960,2425,1564,194,67,464,3340,466,2990,2435,259,2355,16,1320,417,294,2916,683,1249,120,324,1402,2096,2677,476,1696,2761,225,9,2217 0.8709321917690549,0.754312439228042,0.31303318522898527,-0.4572697498231123,-0.022088097488964575,1.2863020037686608,2.202814512277326,0.7150999985878068,-2.3646418191340213,0.7150999985878068,-0.8637791771530676,-0.4572697498231123,1.099790142352336,-0.412958796825298,4.4588127644301565,0.10496721166567786,0.7933537558921767,1.0241336866990407,-0.7722577547913748,0.51638636702171,0.14695211780225223,1.613148049789865,0.9478531474732188,0.06279828060143189,-0.2810734678085235,-0.5912394888767456,0.7150999985878068,-0.06480379588709152,-0.6362392226649662,1.212138715175788,5.321323717121585,-0.3248598804887178 3367 Limb ataxia 6 23 2.7878673511903 0.0053056263332711 P35251,O14773,O00754,Q8IV08,Q12768,Q14108 Drugs and Diseases Human Phenotype Ontology msigdb_hp 153,2,44,51,121,27 2718,44,2,779,841,3149,2586,1312,1471,847,153,2355,1772,121,234,27,51,820,1721,3114,1896,2894,2493 -0.6362392226649662,3.014617485988229,5.884770299255648,0.4356160170646649,0.3949453920319386,-1.0954913801193207,-0.546410842239735,0.10496721166567786,0.020446217421404334,0.3949453920319386,1.4329258820598159,-0.412958796825298,-0.10770002139860704,1.613148049789865,1.1748381597601374,3.6248188309031892,2.7291839700941773,0.4356160170646649,-0.06480379588709152,-1.0023112020703986,-0.15077592925131486,-0.7267490661171271,-0.4572697498231123 3367 Corneal opacity 8 58 2.7809620990384585 0.0054198064263379 O43933,Q9UBM7,Q9NZC9,P10619,P04066,Q13510,O00754,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,1,97,68,6,104,44,23 44,497,1299,537,2719,1226,1104,96,2788,1167,2985,2948,1904,2337,1743,1377,3148,841,6,23,1465,68,164,1042,671,1579,1580,1758,2358,2596,2005,849,1589,973,2089,1183,2919,3131,324,1119,104,327,3302,1188,2750,476,2606,2755,1950,1205,2308,2633,1966,97,1,710,3116,774 3.014617485988229,0.6757140740040977,0.10496721166567786,0.6361522503407359,-0.6362392226649662,0.14695211780225223,0.23036622014532987,1.8251785328251016,-0.6814093200124656,0.18875209347989597,-0.8637791771530676,-0.8179346882917339,-0.1940306860173823,-0.412958796825298,-0.10770002139860704,0.06279828060143189,-1.0954913801193207,0.3949453920319386,5.477203395245907,3.860476447122193,0.020446217421404334,2.1690444425785262,1.3964785412072227,0.27179356591045745,0.51638636702171,-0.022088097488964575,-0.022088097488964575,-0.10770002139860704,-0.412958796825298,-0.546410842239735,-0.23746346936348223,0.3949453920319386,-0.022088097488964575,0.31303318522898527,-0.2810734678085235,0.18875209347989597,-0.7722577547913748,-1.0488191777371687,0.9478531474732188,0.23036622014532987,1.719723884747831,0.9478531474732188,-1.6195456688999854,0.18875209347989597,-0.6362392226649662,0.7150999985878068,-0.546410842239735,-0.6362392226649662,-0.1940306860173823,0.18875209347989597,-0.36882191692968064,-0.546410842239735,-0.1940306860173823,1.8251785328251016,6.354521266861696,0.51638636702171,-1.0023112020703986,0.4760956266149155 3367 Arthritis 10 45 2.7757212900508392 0.0055079402341926 P10321,Q14739,Q13510,Q9NUQ7,P01889,P51798,P06280,P60891,Q14108,P14174 Drugs and Diseases Human Phenotype Ontology msigdb_hp 213,38,104,315,84,307,23,24,27,116 337,3146,3173,1904,787,84,3148,841,23,1569,213,2343,116,1752,1993,2860,597,735,2362,307,640,2007,1590,24,679,1183,1185,2268,104,27,38,1690,2191,1203,1624,2548,1273,1523,816,2046,315,944,1013,3192,2232 0.909473770504105,-1.0954913801193207,-1.142327166182432,-0.1940306860173823,0.4356160170646649,1.9985415804284918,-1.0954913801193207,0.3949453920319386,3.860476447122193,-0.022088097488964575,1.212138715175788,-0.412958796825298,1.613148049789865,-0.10770002139860704,-0.23746346936348223,-0.7267490661171271,0.5964120554641071,0.4760956266149155,-0.412958796825298,0.9860724317343753,0.5564909583357176,-0.23746346936348223,-0.022088097488964575,3.8312646321143324,0.51638636702171,0.18875209347989597,0.18875209347989597,-0.36882191692968064,1.719723884747831,3.6248188309031892,3.1701628794451158,-0.06480379588709152,-0.3248598804887178,0.18875209347989597,-0.022088097488964575,-0.5017540153159744,0.14695211780225223,0.020446217421404334,0.4356160170646649,-0.23746346936348223,0.9860724317343753,0.3540841185619894,0.31303318522898527,-1.142327166182432,-0.3248598804887178 3367 Myosin 8 11 2.7745634798630423 0.0055275845323117 Q13459,Q12965,O94832,O43795,Q9Y4I1,P35580,P60660,P35579 Functions Protein Atlas Molecular function protein_atlas_molecular_function 262,261,319,206,287,387,217,245 407,206,319,245,387,217,261,262,2191,890,287 0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.212138715175788,1.099790142352336,1.099790142352336,-0.3248598804887178,0.3949453920319386,1.0620389315076852 3367 Microfilament motor activity 8 11 2.7745634798630423 0.0055275845323117 Q13459,Q12965,O94832,O43795,Q9Y4I1,P35580,P60660,P35579 Functions GO Molecular function msigdb_gomf 262,261,319,206,287,387,217,245 407,206,319,245,387,217,261,262,2191,890,287 0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.212138715175788,1.099790142352336,1.099790142352336,-0.3248598804887178,0.3949453920319386,1.0620389315076852 3367 Retinal degeneration 9 56 2.77228163712547 0.00556648523712 O14773,P50897,O75503,P42858,Q13510,P04439,O00754,Q96F07,Q6P2Q9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,35,3,100,104,73,44,111,149 2235,44,2,1300,2846,2789,3,1106,725,3255,3148,841,73,2341,1042,2907,671,844,1754,1994,1914,3177,100,2913,3258,35,2596,2175,2916,2741,1246,796,2813,2744,1772,797,104,1856,1060,149,1342,610,2610,2468,172,3012,526,111,1637,1714,1281,2211,622,2894,1652,2897 -0.36882191692968064,3.014617485988229,5.884770299255648,0.10496721166567786,-0.7267490661171271,-0.6814093200124656,5.682423722639393,0.23036622014532987,0.4760956266149155,-1.378937844623164,-1.0954913801193207,0.3949453920319386,2.1011771507196184,-0.412958796825298,0.27179356591045745,-0.7722577547913748,0.51638636702171,0.3949453920319386,-0.10770002139860704,-0.23746346936348223,-0.1940306860173823,-1.142327166182432,1.7549981936289338,-0.7722577547913748,-1.378937844623164,3.2625005214835268,-0.546410842239735,-0.3248598804887178,-0.7722577547913748,-0.6362392226649662,0.14695211780225223,0.4356160170646649,-0.6814093200124656,-0.6362392226649662,-0.10770002139860704,0.4356160170646649,1.719723884747831,-0.15077592925131486,0.27179356591045745,1.469236846394831,0.10496721166567786,0.5964120554641071,-0.546410842239735,-0.4572697498231123,1.3964785412072227,-0.8637791771530676,0.6757140740040977,1.6843250163853651,-0.022088097488964575,-0.06480379588709152,0.14695211780225223,-0.3248598804887178,0.5964120554641071,-0.7267490661171271,-0.022088097488964575,-0.7267490661171271 3367 Liposaccharide metabolic process 7 16 2.7715895687720047 0.0055783323004274 P04066,Q99805,P07686,P16278,P17900,P06865,P06280 Processes and pathways GO Biological process msigdb_gobp 6,202,103,164,46,47,23 2651,841,6,23,47,103,164,46,2268,645,3356,1955,1517,2041,202,284 -0.5912394888767456,0.3949453920319386,5.477203395245907,3.860476447122193,2.9518057266228475,1.719723884747831,1.3964785412072227,3.014617485988229,-0.36882191692968064,0.5564909583357176,-2.77585155562055,-0.1940306860173823,0.020446217421404334,-0.23746346936348223,1.2863020037686608,1.0620389315076852 3367 Myosin complex 8 12 2.771293286230331 0.0055834111176815 Q13459,Q12965,O94832,O43795,Q9Y4I1,P35580,P60660,P35579 Localization GO Cellular component msigdb_gocc 262,261,319,206,287,387,217,245 407,206,319,245,387,217,261,262,2191,1958,890,287 0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.212138715175788,1.099790142352336,1.099790142352336,-0.3248598804887178,-0.1940306860173823,0.3949453920319386,1.0620389315076852 3367 Ceramide metabolic process 7 18 2.7672792523609573 0.0056526312583944 P07686,Q13510,Q96G23,P17900,P06865,P06280,Q8NCC3 Processes and pathways GO Biological process msigdb_gobp 103,104,143,46,47,23,60 1025,1659,668,841,23,47,103,46,3333,2164,2268,645,104,2460,60,143,202,493 0.27179356591045745,-0.06480379588709152,0.51638636702171,0.3949453920319386,3.860476447122193,2.9518057266228475,1.719723884747831,3.014617485988229,-2.1124650811200967,-0.3248598804887178,-0.36882191692968064,0.5564909583357176,1.719723884747831,-0.4572697498231123,2.3368292667835435,1.5054130123499248,1.2863020037686608,0.7150999985878068 3367 Amyloid precursor protein metabolic process 6 19 2.767191447402916 0.0056541540281396 Q15392,P42574,P62942,Q9NQC3,P27695,Q92542 Processes and pathways GO Biological process msigdb_gobp 0,260,75,384,304,159 2425,2338,304,361,260,2085,1052,75,2962,1402,2526,1405,0,159,2885,1428,1429,384,2051 -0.4572697498231123,-0.412958796825298,0.9860724317343753,0.8709321917690549,1.099790142352336,-0.2810734678085235,0.27179356591045745,2.0670777141599412,-0.8179346882917339,0.06279828060143189,-0.5017540153159744,0.06279828060143189,9.266342596549883,1.4329258820598159,-0.7267490661171271,0.06279828060143189,0.06279828060143189,0.8709321917690549,-0.23746346936348223 3367 Vesicle cytoskeletal trafficking 10 21 2.7660229870971724 0.0056744534714341 O14617,O00203,Q14204,P42858,O00159,Q12965,O94832,O43795,Q9Y4I1,P27695 Processes and pathways GO Biological process msigdb_gobp 183,408,328,100,407,261,319,206,287,304 407,408,1369,183,1302,206,319,1744,304,2166,100,415,2522,2524,261,328,1515,890,2324,834,287 0.7933537558921767,0.7933537558921767,0.06279828060143189,1.3231682601538646,0.10496721166567786,1.249292736644776,0.9478531474732188,-0.10770002139860704,0.9860724317343753,-0.3248598804887178,1.7549981936289338,0.7933537558921767,-0.5017540153159744,-0.5017540153159744,1.099790142352336,0.9478531474732188,0.020446217421404334,0.3949453920319386,-0.36882191692968064,0.4356160170646649,1.0620389315076852 3367 Hydrops fetalis 12 45 2.7647515642977063 0.005696616323783 P10619,Q14739,Q07020,Q13510,P16278,P62899,P61313,P18077,P62847,Q8NCM8,P42766,P61353 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,38,134,104,164,198,74,165,197,181,177,275 1560,1167,1459,1306,2654,841,1378,1230,68,1231,164,165,1177,2259,3095,2354,177,2956,292,3227,597,2176,851,910,74,275,1054,680,855,197,1681,198,2264,2091,2268,134,104,38,181,2471,924,1530,3291,1719,2897 -0.022088097488964575,0.18875209347989597,0.020446217421404334,0.10496721166567786,-0.5912394888767456,0.3949453920319386,0.06279828060143189,0.14695211780225223,2.1690444425785262,0.14695211780225223,1.3964785412072227,1.3964785412072227,0.18875209347989597,-0.36882191692968064,-1.0023112020703986,-0.412958796825298,1.3598932144259221,-0.8179346882917339,1.0241336866990407,-1.2838097038521317,0.5964120554641071,-0.3248598804887178,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,-0.2810734678085235,-0.36882191692968064,1.5414559276361184,1.719723884747831,3.1701628794451158,1.3598932144259221,-0.4572697498231123,0.3540841185619894,0.020446217421404334,-1.52282763066264,-0.06480379588709152,-0.7267490661171271 3367 Lipid biosynthesis 9 55 2.7634380477888483 0.005719594898643 Q15392,Q9UBM7,Q14739,Q15125,Q96N66,Q96G23,Q92604,Q16850,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 0,1,38,7,144,143,223,157,30 2060,1163,954,1452,411,2247,463,2070,467,2731,3333,635,30,2000,215,793,597,1114,1762,1679,2807,3339,1185,1118,645,1252,38,7,3075,984,0,2024,446,157,1193,557,1269,2758,3249,485,223,3322,143,144,3050,881,1639,1962,3142,2312,336,767,1,622,2713 -0.2810734678085235,0.18875209347989597,0.31303318522898527,0.020446217421404334,0.7933537558921767,-0.36882191692968064,0.7150999985878068,-0.2810734678085235,0.7150999985878068,-0.6362392226649662,-2.1124650811200967,0.5564909583357176,3.4751842548839553,-0.23746346936348223,1.212138715175788,0.4356160170646649,0.5964120554641071,0.23036622014532987,-0.10770002139860704,-0.06480379588709152,-0.6814093200124656,-2.3139063625418146,0.18875209347989597,0.23036622014532987,0.5564909583357176,0.14695211780225223,3.1701628794451158,5.347423495313898,-0.9559681035265681,0.31303318522898527,9.266342596549883,-0.23746346936348223,0.754312439228042,1.4329258820598159,0.18875209347989597,0.6361522503407359,0.14695211780225223,-0.6362392226649662,-1.3312935370263337,0.7150999985878068,1.212138715175788,-1.8148607923698326,1.5054130123499248,1.5054130123499248,-0.9097905400273109,0.3949453920319386,-0.022088097488964575,-0.1940306860173823,-1.0488191777371687,-0.36882191692968064,0.9478531474732188,0.4760956266149155,6.354521266861696,0.5964120554641071,-0.5912394888767456 3367 Entry into host 8 30 2.7568395219231325 0.0058362987041205 P02786,Q9BTY2,Q8WTV0,O15118,P35613,P11279,Q14108,O14786 Processes and pathways GO Biological process msigdb_gobp 67,4,110,81,305,90,27,127 127,81,2424,67,1309,1826,1037,1464,2159,1466,90,542,3091,2949,3242,305,2955,1051,2525,27,327,1253,2677,110,1353,1633,4,2226,713,775 1.5773671103553362,2.032866242545018,-0.4572697498231123,2.202814512277326,0.10496721166567786,-0.15077592925131486,0.27179356591045745,0.020446217421404334,-0.3248598804887178,0.020446217421404334,1.8948765913387664,0.6361522503407359,-1.0023112020703986,-0.8179346882917339,-1.3312935370263337,0.9860724317343753,-0.8179346882917339,0.27179356591045745,-0.5017540153159744,3.6248188309031892,0.9478531474732188,0.14695211780225223,-0.5912394888767456,1.6843250163853651,0.10496721166567786,-0.022088097488964575,5.6569309364282425,-0.3248598804887178,0.51638636702171,0.4760956266149155 3367 Abnormal pharynx morphology 10 37 2.746730869568654 0.0060192505083207 P41229,Q13510,P16278,P15586,P13051,Q93008,P01889,P54802,Q15833,P60891 Drugs and Diseases Human Phenotype Ontology msigdb_hp 33,104,164,13,163,311,84,54,420,24 2573,1822,3146,1558,2722,1825,84,2582,163,13,164,2076,636,33,2513,1918,735,599,736,54,2008,24,1846,2268,2963,1120,104,420,3246,1791,2197,2549,311,2550,1799,1007,426 -0.546410842239735,-0.15077592925131486,-1.0954913801193207,-0.022088097488964575,-0.6362392226649662,-0.15077592925131486,1.9985415804284918,-0.546410842239735,1.3964785412072227,4.896921049154351,1.3964785412072227,-0.2810734678085235,0.5564909583357176,3.3236578103542245,-0.5017540153159744,-0.1940306860173823,0.4760956266149155,0.5964120554641071,0.4760956266149155,2.664757267155283,-0.23746346936348223,3.8312646321143324,-0.15077592925131486,-0.36882191692968064,-0.8179346882917339,0.23036622014532987,1.719723884747831,0.7933537558921767,-1.3312935370263337,-0.10770002139860704,-0.3248598804887178,-0.5017540153159744,0.9860724317343753,-0.5017540153159744,-0.10770002139860704,0.31303318522898527,0.7933537558921767 3367 Organic anion transport 16 39 2.742003426536203 0.0061065704582317 P80404,O95563,P53985,P11166,P30825,P28288,P07602,P53007,Q15041,Q99808,Q9H2D1,P14174,Q9UBX3,Q9HC21,Q9NZJ7,O14745 Processes and pathways GO Biological process msigdb_gobp 65,462,294,466,259,258,17,510,519,225,490,116,495,192,162,433 433,1373,2848,1984,2428,462,2155,788,1309,17,1464,466,1040,789,116,258,259,2355,510,294,2916,65,1248,645,519,1779,2677,2606,1696,561,225,490,2976,2212,192,162,495,2713,2567 0.754312439228042,0.06279828060143189,-0.7267490661171271,-0.23746346936348223,-0.4572697498231123,0.7150999985878068,-0.3248598804887178,0.4356160170646649,0.10496721166567786,4.3750256940936305,0.020446217421404334,0.7150999985878068,0.27179356591045745,0.4356160170646649,1.613148049789865,1.099790142352336,1.099790142352336,-0.412958796825298,0.6757140740040977,1.0241336866990407,-0.7722577547913748,2.2364769766120918,0.14695211780225223,0.5564909583357176,0.6757140740040977,-0.10770002139860704,-0.5912394888767456,-0.546410842239735,-0.06480379588709152,0.6361522503407359,1.212138715175788,0.7150999985878068,-0.8179346882917339,-0.3248598804887178,1.3231682601538646,1.4329258820598159,0.7150999985878068,-0.5912394888767456,-0.5017540153159744 3367 Lipid homeostasis 8 23 2.7384573945119706 0.0061728158049274 Q5BJF2,Q8WTV0,Q9NQC3,O15260,O15118,Q9Y6C9,Q6YHU6,P61916 Processes and pathways GO Biological process msigdb_gobp 10,110,384,49,81,151,279,25 2497,81,1101,49,633,1175,1234,1579,361,25,1118,645,2674,10,690,279,110,2763,1003,384,831,3115,151 -0.5017540153159744,2.032866242545018,0.23036622014532987,2.793240616952005,0.5564909583357176,0.18875209347989597,0.14695211780225223,-0.022088097488964575,0.8709321917690549,3.772633277255873,0.23036622014532987,0.5564909583357176,-0.5912394888767456,5.216435956950591,0.51638636702171,1.0620389315076852,1.6843250163853651,-0.6362392226649662,0.31303318522898527,0.8709321917690549,0.4356160170646649,-1.0023112020703986,1.469236846394831 3367 Incoordination 11 70 2.731856459125301 0.0062978572633713 O14773,O75503,P42858,Q8TC12,Q13510,O00754,P27635,Q13501,P07602,O75165,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 2,3,100,172,104,44,195,234,17,300,162 2718,44,2,497,779,1301,1901,300,3277,3,1031,2337,841,730,17,1667,1040,1312,413,2349,195,847,1997,2861,2354,100,1839,2084,2446,510,2262,2176,1590,2741,3154,515,2920,1599,1772,234,104,1123,328,2674,2096,1862,2028,1613,919,1866,610,172,1205,2827,996,1074,1075,1141,1714,2629,2211,2049,1721,2220,162,1896,1442,660,889,1368 -0.6362392226649662,3.014617485988229,5.884770299255648,0.6757140740040977,0.4356160170646649,0.10496721166567786,-0.1940306860173823,0.9860724317343753,-1.4747054833332776,5.682423722639393,0.27179356591045745,-0.412958796825298,0.3949453920319386,0.4760956266149155,4.3750256940936305,-0.06480379588709152,0.27179356591045745,0.10496721166567786,0.7933537558921767,-0.412958796825298,1.2863020037686608,0.3949453920319386,-0.23746346936348223,-0.7267490661171271,-0.412958796825298,1.7549981936289338,-0.15077592925131486,-0.2810734678085235,-0.4572697498231123,0.6757140740040977,-0.36882191692968064,-0.3248598804887178,-0.022088097488964575,-0.6362392226649662,-1.0954913801193207,0.6757140740040977,-0.7722577547913748,-0.022088097488964575,-0.10770002139860704,1.1748381597601374,1.719723884747831,0.23036622014532987,0.9478531474732188,-0.5912394888767456,-0.2810734678085235,-0.15077592925131486,-0.23746346936348223,-0.022088097488964575,0.3540841185619894,-0.15077592925131486,0.5964120554641071,1.3964785412072227,0.18875209347989597,-0.6814093200124656,0.31303318522898527,0.27179356591045745,0.27179356591045745,0.23036622014532987,-0.06480379588709152,-0.546410842239735,-0.3248598804887178,-0.23746346936348223,-0.06480379588709152,-0.3248598804887178,1.4329258820598159,-0.15077592925131486,0.06279828060143189,0.5564909583357176,0.3949453920319386,0.10496721166567786 3367 Immunoglobulin-like domain superfamily [IPR036179] 7 14 2.7182610501508964 0.0065626038169539 P10321,P04439,P55899,Q9BX67,P01889,P35613,P43121 Sequence InterPro Superfamily interpro_homologous_superfamily 213,73,43,313,84,305,342 1558,358,84,73,213,305,342,43,1855,1948,1625,313,3209,775 -0.022088097488964575,0.8709321917690549,1.9985415804284918,2.1011771507196184,1.212138715175788,0.9860724317343753,0.909473770504105,3.0458947300580568,-0.15077592925131486,-0.1940306860173823,-0.022088097488964575,0.9860724317343753,-1.1893259001279373,0.4760956266149155 3367 Immunoglobulin-like domain [IPR007110] 7 14 2.7182610501508964 0.0065626038169539 P10321,P04439,P55899,Q9BX67,P01889,P35613,P43121 Sequence InterPro Domain interpro_domain 213,73,43,313,84,305,342 1558,358,84,73,213,305,342,43,1855,1948,1625,313,3209,775 -0.022088097488964575,0.8709321917690549,1.9985415804284918,2.1011771507196184,1.212138715175788,0.9860724317343753,0.909473770504105,3.0458947300580568,-0.15077592925131486,-0.1940306860173823,-0.022088097488964575,0.9860724317343753,-1.1893259001279373,0.4760956266149155 3367 Transition metal ion homeostasis 10 24 2.716383398930039 0.0065999438668087 O14617,Q8N511,O00203,Q9H3K6,Q658P3,P02786,P04179,P05067,Q15904,Q15043 Processes and pathways GO Biological process msigdb_gobp 183,421,408,267,36,67,464,14,48,330 408,183,1901,1902,1375,2151,2902,67,464,14,1908,544,1476,1578,3177,737,2376,2526,330,48,36,421,267,1295 0.7933537558921767,1.3231682601538646,-0.1940306860173823,-0.1940306860173823,0.06279828060143189,-0.3248598804887178,-0.7722577547913748,2.202814512277326,0.7150999985878068,4.815860976496678,-0.1940306860173823,0.6361522503407359,0.020446217421404334,-0.022088097488964575,-1.142327166182432,0.4760956266149155,-0.412958796825298,-0.5017540153159744,0.9478531474732188,2.888645998928826,3.201023198065498,0.7933537558921767,1.099790142352336,0.14695211780225223 3367 Gait ataxia 11 68 2.714581964822921 0.006635947676739 P35251,O14773,P42858,O00754,P27635,Q13501,P07602,O15118,Q8IV08,Q14108,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 153,2,100,44,195,234,17,81,51,27,162 2718,44,2,779,81,1301,1900,358,465,2586,17,1987,1040,1312,413,439,1042,671,2162,3240,1832,1994,195,2439,847,153,2861,2355,100,2083,2446,1325,2363,1589,1590,972,3301,2920,2182,1772,3132,1119,234,1251,27,1406,802,1189,1862,2756,51,2610,2394,564,1522,2301,1075,268,1721,2633,2220,577,162,1896,1442,1014,2894,2493 -0.6362392226649662,3.014617485988229,5.884770299255648,0.4356160170646649,2.032866242545018,0.10496721166567786,-0.1940306860173823,0.8709321917690549,0.7150999985878068,-0.546410842239735,4.3750256940936305,-0.23746346936348223,0.27179356591045745,0.10496721166567786,0.7933537558921767,0.754312439228042,0.27179356591045745,0.51638636702171,-0.3248598804887178,-1.3312935370263337,-0.15077592925131486,-0.23746346936348223,1.2863020037686608,-0.4572697498231123,0.3949453920319386,1.4329258820598159,-0.7267490661171271,-0.412958796825298,1.7549981936289338,-0.2810734678085235,-0.4572697498231123,0.10496721166567786,-0.412958796825298,-0.022088097488964575,-0.022088097488964575,0.31303318522898527,-1.6195456688999854,-0.7722577547913748,-0.3248598804887178,-0.10770002139860704,-1.0488191777371687,0.23036622014532987,1.1748381597601374,0.14695211780225223,3.6248188309031892,0.06279828060143189,0.4356160170646649,0.18875209347989597,-0.15077592925131486,-0.6362392226649662,2.7291839700941773,-0.546410842239735,-0.412958796825298,0.6361522503407359,0.020446217421404334,-0.36882191692968064,0.27179356591045745,1.099790142352336,-0.06480379588709152,-0.546410842239735,-0.3248598804887178,0.6361522503407359,1.4329258820598159,-0.15077592925131486,0.06279828060143189,0.31303318522898527,-0.7267490661171271,-0.4572697498231123 3367 Ribosomal large subunit assembly 13 23 2.707900885048637 0.006771024046873 Q9BYC9,P46777,Q02878,Q9NU22,P27635,P46087,P63173,Q9H7B2,Q9NQ55,P62750,Q8TDN6,P39023,P83731 Processes and pathways GO Biological process msigdb_gobp 204,292,366,241,195,545,140,451,621,363,422,118,155 2584,195,118,545,292,363,2264,140,155,366,860,1336,1131,422,204,451,621,241,2131,1645,657,1968,2715 -0.546410842239735,1.2863020037686608,1.613148049789865,0.6361522503407359,1.0241336866990407,0.8709321917690549,-0.36882191692968064,1.5054130123499248,1.4329258820598159,0.8709321917690549,0.3949453920319386,0.10496721166567786,0.23036622014532987,0.7933537558921767,1.2863020037686608,0.754312439228042,0.5964120554641071,1.1748381597601374,-0.2810734678085235,-0.022088097488964575,0.5564909583357176,-0.1940306860173823,-0.5912394888767456 3367 Actin filament based movement 10 31 2.7053649133551763 0.0068229392495908 Q9UM22,Q12965,Q13459,O94832,O43795,Q99996,Q9Y4I1,P35580,P60660,P35579 Processes and pathways GO Biological process msigdb_gobp 8,261,262,319,206,79,287,387,217,245 1450,407,1369,1302,206,2244,319,2796,2798,2588,1173,1109,1578,245,387,217,261,262,1402,744,745,2191,874,1270,1636,79,703,3086,8,890,287 0.020446217421404334,0.7933537558921767,0.06279828060143189,0.10496721166567786,1.249292736644776,-0.36882191692968064,0.9478531474732188,-0.6814093200124656,-0.6814093200124656,-0.546410842239735,0.18875209347989597,0.23036622014532987,-0.022088097488964575,1.1373892537486945,0.8322262551325478,1.212138715175788,1.099790142352336,1.099790142352336,0.06279828060143189,0.4760956266149155,0.4760956266149155,-0.3248598804887178,0.3949453920319386,0.14695211780225223,-0.022088097488964575,2.0670777141599412,0.51638636702171,-0.9559681035265681,5.347423495313898,0.3949453920319386,1.0620389315076852 3367 Immunoglobulin-like fold [IPR013783] 10 36 2.6946320948697027 0.0070466389100449 P10321,Q8IZA0,O00462,P04439,P55899,Q9BX67,P01889,P35613,Q14118,P43121 Sequence InterPro Superfamily interpro_homologous_superfamily 213,39,40,73,43,313,84,305,327,342 40,720,1822,1558,1167,630,358,2725,84,73,213,1109,305,342,1928,43,1183,2962,2091,3245,1855,327,1125,1499,2685,1948,2030,39,2544,1625,1633,313,2412,3209,2641,775 3.1081955602316613,0.4760956266149155,-0.15077592925131486,-0.022088097488964575,0.18875209347989597,0.5564909583357176,0.8709321917690549,-0.6362392226649662,1.9985415804284918,2.1011771507196184,1.212138715175788,0.23036622014532987,0.9860724317343753,0.909473770504105,-0.1940306860173823,3.0458947300580568,0.18875209347989597,-0.8179346882917339,-0.2810734678085235,-1.3312935370263337,-0.15077592925131486,0.9478531474732188,0.23036622014532987,0.020446217421404334,-0.5912394888767456,-0.1940306860173823,-0.23746346936348223,3.13922056117222,-0.5017540153159744,-0.022088097488964575,-0.022088097488964575,0.9860724317343753,-0.412958796825298,-1.1893259001279373,-0.546410842239735,0.4760956266149155 3367 Abnormal systemic arterial morphology 32 155 2.6942367547208224 0.0070550031609899 Q9UBM7,Q9H7D7,Q07020,P05067,P07602,P61916,P61353,Q9NZJ7,Q9Y4A5,P46777,P16278,P18077,P17900,P06865,P42766,O75531,P10253,P10619,Q14839,P62899,P61313,P62847,Q6ZXV5,O15118,P01889,Q8WYQ5,Q9NZC9,Q86V48,P19022,P42858,P07686,Q13510 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,268,134,14,17,25,275,162,174,292,164,165,46,47,177,301,59,68,199,198,74,197,347,81,84,87,97,98,214,100,103,104 2235,81,2331,3146,498,2719,1226,1104,1029,2788,960,2789,1167,301,725,3173,1904,727,2066,3255,84,3148,841,14,730,47,17,103,1230,59,68,1748,2990,2073,164,46,1042,165,732,214,671,1109,2349,1752,1993,1754,1670,2733,2164,2353,1579,1580,2259,2000,1389,2168,3095,2513,177,100,2996,292,3227,1049,2084,546,1588,849,2007,1589,2916,1930,1590,851,910,74,275,25,2599,1054,2742,680,855,197,1681,198,2264,2089,978,742,682,2815,2182,134,797,2376,104,1856,1060,2021,199,3302,1188,3196,2924,2753,2606,1864,1865,347,1342,1343,610,98,611,811,2468,2471,87,2548,1205,1273,924,1350,349,927,996,3201,1636,1637,2207,1281,821,2629,268,3082,2563,765,1966,97,162,1,1013,2637,2980,710,889,624,1652,3192,2232,174,952,774,2418 -0.36882191692968064,2.032866242545018,-0.412958796825298,-1.0954913801193207,0.6757140740040977,-0.6362392226649662,0.14695211780225223,0.23036622014532987,0.27179356591045745,-0.6814093200124656,0.31303318522898527,-0.6814093200124656,0.18875209347989597,0.9860724317343753,0.4760956266149155,-1.142327166182432,-0.1940306860173823,0.4760956266149155,-0.2810734678085235,-1.378937844623164,1.9985415804284918,-1.0954913801193207,0.3949453920319386,4.815860976496678,0.4760956266149155,2.9518057266228475,4.3750256940936305,1.719723884747831,0.14695211780225223,2.4362503004565204,2.1690444425785262,-0.10770002139860704,-0.8637791771530676,-0.2810734678085235,1.3964785412072227,3.014617485988229,0.27179356591045745,1.3964785412072227,0.4760956266149155,1.212138715175788,0.51638636702171,0.23036622014532987,-0.412958796825298,-0.10770002139860704,-0.23746346936348223,-0.10770002139860704,-0.06480379588709152,-0.6362392226649662,-0.3248598804887178,-0.412958796825298,-0.022088097488964575,-0.022088097488964575,-0.36882191692968064,-0.23746346936348223,0.06279828060143189,-0.3248598804887178,-1.0023112020703986,-0.5017540153159744,1.3598932144259221,1.7549981936289338,-0.8637791771530676,1.0241336866990407,-1.2838097038521317,0.27179356591045745,-0.2810734678085235,0.6361522503407359,-0.022088097488964575,0.3949453920319386,-0.23746346936348223,-0.022088097488964575,-0.7722577547913748,-0.1940306860173823,-0.022088097488964575,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,3.772633277255873,-0.546410842239735,0.27179356591045745,-0.6362392226649662,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,-0.2810734678085235,0.31303318522898527,0.4760956266149155,0.51638636702171,-0.6814093200124656,-0.3248598804887178,1.5414559276361184,0.4356160170646649,-0.412958796825298,1.719723884747831,-0.15077592925131486,0.27179356591045745,-0.23746346936348223,1.2863020037686608,-1.6195456688999854,0.18875209347989597,-1.1893259001279373,-0.7722577547913748,-0.6362392226649662,-0.546410842239735,-0.15077592925131486,-0.15077592925131486,0.909473770504105,0.10496721166567786,0.10496721166567786,0.5964120554641071,1.790149299150869,0.5964120554641071,0.4356160170646649,-0.4572697498231123,-0.4572697498231123,1.9641025522127773,-0.5017540153159744,0.18875209347989597,0.14695211780225223,0.3540841185619894,0.10496721166567786,0.909473770504105,0.3540841185619894,0.31303318522898527,-1.1893259001279373,-0.022088097488964575,-0.022088097488964575,-0.3248598804887178,0.14695211780225223,0.4356160170646649,-0.546410842239735,1.099790142352336,-0.9559681035265681,-0.5017540153159744,0.4760956266149155,-0.1940306860173823,1.8251785328251016,1.4329258820598159,6.354521266861696,0.31303318522898527,-0.546410842239735,-0.8179346882917339,0.51638636702171,0.3949453920319386,0.5964120554641071,-0.022088097488964575,-1.142327166182432,-0.3248598804887178,1.3964785412072227,0.3540841185619894,0.4760956266149155,-0.412958796825298 3367 Abnormality of the autonomic nervous system 8 65 2.6871848887079204 0.0072057055196759 Q9UBM7,P35251,P07686,Q99996,P42892,P07602,P06280,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,153,103,79,16,17,23,162 497,1025,1659,2331,1301,895,1029,300,2792,2337,841,23,17,103,413,3240,1752,153,2082,2000,3128,2355,16,906,3178,1325,2007,2091,515,2182,1772,1334,1406,2674,1780,2106,2756,1864,919,200,811,876,2548,1205,1273,698,1277,996,1074,816,1075,2480,79,821,2629,2211,2774,1722,765,162,1,889,950,2717,837 0.6757140740040977,0.27179356591045745,-0.06480379588709152,-0.412958796825298,0.10496721166567786,0.3540841185619894,0.27179356591045745,0.9860724317343753,-0.6814093200124656,-0.412958796825298,0.3949453920319386,3.860476447122193,4.3750256940936305,1.719723884747831,0.7933537558921767,-1.3312935370263337,-0.10770002139860704,1.4329258820598159,-0.2810734678085235,-0.23746346936348223,-1.0488191777371687,-0.412958796825298,4.4588127644301565,0.3540841185619894,-1.142327166182432,0.10496721166567786,-0.23746346936348223,-0.2810734678085235,0.6757140740040977,-0.3248598804887178,-0.10770002139860704,0.10496721166567786,0.06279828060143189,-0.5912394888767456,-0.10770002139860704,-0.2810734678085235,-0.6362392226649662,-0.15077592925131486,0.3540841185619894,1.2863020037686608,0.4356160170646649,0.3949453920319386,-0.5017540153159744,0.18875209347989597,0.14695211780225223,0.51638636702171,0.14695211780225223,0.31303318522898527,0.27179356591045745,0.4356160170646649,0.27179356591045745,-0.4572697498231123,2.0670777141599412,0.4356160170646649,-0.546410842239735,-0.3248598804887178,-0.6362392226649662,-0.06480379588709152,0.4760956266149155,1.4329258820598159,6.354521266861696,0.3949453920319386,0.3540841185619894,-0.5912394888767456,0.4356160170646649 3367 Carbohydrate catabolic process 6 50 2.6838550603131983 0.0072778650090208 P07686,O00462,Q14108,P17900,P05067,P10253 Processes and pathways GO Biological process msigdb_gobp 103,40,27,46,14,59 40,1976,1984,1985,2795,1463,1568,2582,14,2585,1169,2157,103,1569,502,2505,59,1571,1829,164,1041,46,3280,2907,440,508,2738,636,2515,1052,1482,2261,2172,1679,1845,1240,1593,2742,1598,1934,2668,2812,645,27,649,818,1435,2130,947,770 3.1081955602316613,-0.23746346936348223,-0.23746346936348223,-0.23746346936348223,-0.6814093200124656,0.020446217421404334,-0.022088097488964575,-0.546410842239735,4.815860976496678,-0.546410842239735,0.18875209347989597,-0.3248598804887178,1.719723884747831,-0.022088097488964575,0.6757140740040977,-0.5017540153159744,2.4362503004565204,-0.022088097488964575,-0.15077592925131486,1.3964785412072227,0.27179356591045745,3.014617485988229,-1.4747054833332776,-0.7722577547913748,0.754312439228042,0.6757140740040977,-0.6362392226649662,0.5564909583357176,-0.5017540153159744,0.27179356591045745,0.020446217421404334,-0.36882191692968064,-0.3248598804887178,-0.06480379588709152,-0.15077592925131486,0.14695211780225223,-0.022088097488964575,-0.6362392226649662,-0.022088097488964575,-0.1940306860173823,-0.5912394888767456,-0.6814093200124656,0.5564909583357176,3.6248188309031892,0.5564909583357176,0.4356160170646649,0.06279828060143189,-0.2810734678085235,0.3540841185619894,0.4760956266149155 3367 Cytoskeletal motor activity 11 31 2.68066205004239 0.0073476678848403 Q14204,Q13459,Q12965,O94832,O43795,Q9Y4I1,Q8NCM8,Q2M1P5,P35580,P60660,P35579 Functions GO Molecular function msigdb_gomf 328,262,261,319,206,287,181,371,387,217,245 953,407,206,1029,319,1306,1033,2166,245,387,2005,217,1184,2669,2524,261,2092,262,328,1690,371,2191,181,1208,1077,1804,1892,890,1727,834,287 0.31303318522898527,0.7933537558921767,1.249292736644776,0.27179356591045745,0.9478531474732188,0.10496721166567786,0.27179356591045745,-0.3248598804887178,1.1373892537486945,0.8322262551325478,-0.23746346936348223,1.212138715175788,0.18875209347989597,-0.5912394888767456,-0.5017540153159744,1.099790142352336,-0.2810734678085235,1.099790142352336,0.9478531474732188,-0.06480379588709152,0.8709321917690549,-0.3248598804887178,1.3598932144259221,0.18875209347989597,0.27179356591045745,-0.10770002139860704,-0.15077592925131486,0.3949453920319386,-0.06480379588709152,0.4356160170646649,1.0620389315076852 3367 Abnormal rib cage morphology 14 76 2.6752779446412096 0.0074667318529946 O43933,Q9UBM7,Q86V48,Q99575,P04066,Q14739,P16278,O00754,P15586,Q8NCM8,Q12768,P51798,Q92917,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,1,98,266,6,38,164,44,13,181,121,307,281,54 44,497,3211,2576,96,1902,1167,1980,301,3238,1904,727,1743,2068,1377,3148,6,1037,13,164,2991,732,2348,1109,1993,2949,3241,1670,3095,3128,793,2360,1585,307,54,1846,3229,1183,742,682,3130,2815,2744,121,1119,2376,38,1780,2024,2750,521,2533,2753,691,1864,1865,1949,98,181,2471,1624,281,2476,1523,927,2207,266,1142,1889,2308,1,3022,2980,2982,2642,2418 3.014617485988229,0.6757140740040977,-1.2364869532593843,-0.546410842239735,1.8251785328251016,-0.1940306860173823,0.18875209347989597,-0.23746346936348223,0.9860724317343753,-1.3312935370263337,-0.1940306860173823,0.4760956266149155,-0.10770002139860704,-0.2810734678085235,0.06279828060143189,-1.0954913801193207,5.477203395245907,0.27179356591045745,4.896921049154351,1.3964785412072227,-0.8637791771530676,0.4760956266149155,-0.412958796825298,0.23036622014532987,-0.23746346936348223,-0.8179346882917339,-1.3312935370263337,-0.06480379588709152,-1.0023112020703986,-1.0488191777371687,0.4356160170646649,-0.412958796825298,-0.022088097488964575,0.9860724317343753,2.664757267155283,-0.15077592925131486,-1.2838097038521317,0.18875209347989597,0.4760956266149155,0.51638636702171,-1.0488191777371687,-0.6814093200124656,-0.6362392226649662,1.613148049789865,0.23036622014532987,-0.412958796825298,3.1701628794451158,-0.10770002139860704,-0.23746346936348223,-0.6362392226649662,0.6757140740040977,-0.5017540153159744,-0.6362392226649662,0.51638636702171,-0.15077592925131486,-0.15077592925131486,-0.1940306860173823,1.790149299150869,1.3598932144259221,-0.4572697498231123,-0.022088097488964575,1.0620389315076852,-0.4572697498231123,0.020446217421404334,0.3540841185619894,-0.3248598804887178,1.099790142352336,0.23036622014532987,-0.15077592925131486,-0.36882191692968064,6.354521266861696,-0.8637791771530676,-0.8179346882917339,-0.8179346882917339,-0.546410842239735,-0.412958796825298 3367 Early endosome 23 98 2.6721577356567963 0.0075365213033988 P05067,Q9Y4I1,O60879,Q92542,Q9UIQ6,Q8IV08,P11717,P27695,O75165,Q15043,P02786,Q9BUN8,Q7Z3U7,P04439,O43795,P01889,P10321,P42858,Q13510,Q12768,Q9Y2I1,Q07954,O14786 Localization GO Cellular component msigdb_gocc 14,287,138,159,32,51,53,304,300,330,67,335,201,73,206,84,213,100,104,121,126,120,127 2572,127,1098,1103,2146,206,2424,2242,138,300,1981,501,319,437,84,67,2155,73,14,213,3124,53,2433,2732,2436,3126,304,1670,2659,507,1477,3242,3066,2355,2955,100,1927,1243,737,2011,2522,1183,742,120,121,2526,104,3157,1122,2672,2922,330,803,3102,689,1263,2027,479,988,693,201,1346,51,2290,1073,159,563,2476,1353,3349,1074,1713,2768,3221,335,1804,936,3141,2403,3165,2226,945,532,1088,32,3024,2840,2893,832,2054,2322,3170,2137,1650,833,126,287,3172 -0.546410842239735,1.5773671103553362,0.23036622014532987,0.23036622014532987,-0.3248598804887178,1.249292736644776,-0.4572697498231123,-0.36882191692968064,1.5054130123499248,0.9860724317343753,-0.23746346936348223,0.6757140740040977,0.9478531474732188,0.754312439228042,1.9985415804284918,2.202814512277326,-0.3248598804887178,2.1011771507196184,4.815860976496678,1.212138715175788,-1.0488191777371687,2.664757267155283,-0.4572697498231123,-0.6362392226649662,-0.4572697498231123,-1.0488191777371687,0.9860724317343753,-0.06480379588709152,-0.5912394888767456,0.6757140740040977,0.020446217421404334,-1.3312935370263337,-0.9559681035265681,-0.412958796825298,-0.8179346882917339,1.7549981936289338,-0.1940306860173823,0.14695211780225223,0.4760956266149155,-0.23746346936348223,-0.5017540153159744,0.18875209347989597,0.4760956266149155,1.613148049789865,1.613148049789865,-0.5017540153159744,1.719723884747831,-1.0954913801193207,0.23036622014532987,-0.5912394888767456,-0.7722577547913748,0.9478531474732188,0.4356160170646649,-1.0023112020703986,0.51638636702171,0.14695211780225223,-0.23746346936348223,0.7150999985878068,0.31303318522898527,0.51638636702171,1.2863020037686608,0.10496721166567786,2.7291839700941773,-0.36882191692968064,0.27179356591045745,1.4329258820598159,0.6361522503407359,-0.4572697498231123,0.10496721166567786,-2.5177406421925412,0.27179356591045745,-0.06480379588709152,-0.6362392226649662,-1.2364869532593843,0.9478531474732188,-0.10770002139860704,0.3540841185619894,-1.0488191777371687,-0.412958796825298,-1.0954913801193207,-0.3248598804887178,0.3540841185619894,0.6757140740040977,0.27179356591045745,3.354118052447859,-0.8637791771530676,-0.6814093200124656,-0.7267490661171271,0.4356160170646649,-0.23746346936348223,-0.36882191692968064,-1.0954913801193207,-0.2810734678085235,-0.022088097488964575,0.4356160170646649,1.613148049789865,1.0620389315076852,-1.0954913801193207 3367 Fcgamma receptor fcgr dependent phagocytosis 10 32 2.665661708485254 0.0076836968289253 Q7L576,O15143,Q14185,Q13459,Q12965,Q96F07,Q9Y4I1,Q8IV08,Q9UQB8,P35579 Processes and pathways Reactome Pathways msigdb_reactome 263,338,101,262,261,111,287,51,29,245 407,1369,338,2786,2143,2158,2071,1472,1669,3126,1670,245,2263,1117,3097,2370,2012,1245,2268,261,262,101,1189,263,51,2037,111,1278,2225,29,661,287 0.7933537558921767,0.06279828060143189,0.909473770504105,-0.6814093200124656,-0.3248598804887178,-0.3248598804887178,-0.2810734678085235,0.020446217421404334,-0.06480379588709152,-1.0488191777371687,-0.06480379588709152,1.1373892537486945,-0.36882191692968064,0.23036622014532987,-1.0023112020703986,-0.412958796825298,-0.23746346936348223,0.14695211780225223,-0.36882191692968064,1.099790142352336,1.099790142352336,1.7549981936289338,0.18875209347989597,1.099790142352336,2.7291839700941773,-0.23746346936348223,1.6843250163853651,0.14695211780225223,-0.3248598804887178,3.535260987655072,0.5564909583357176,1.0620389315076852 3367 Late endosome 17 65 2.657694570070088 0.0078677160370008 Q658P3,Q9Y2Q5,Q9BUN8,P11279,P42858,Q13501,Q9Y4I1,P07602,O15118,Q8IV08,Q99538,P11717,Q99570,P13473,Q14108,Q9NZJ7,Q15043 Localization GO Cellular component msigdb_gocc 36,136,335,90,100,234,287,17,81,51,20,53,350,26,27,162,330 2572,1098,81,1103,3062,1899,3235,2986,17,3312,1748,2587,90,53,26,967,592,3126,1670,3066,100,908,1243,742,234,27,370,330,479,36,690,51,752,1953,2290,617,2760,2476,1878,1425,1636,1074,758,20,350,2768,700,335,1286,1884,3141,2403,3165,763,2219,162,2226,3022,1088,623,3170,833,136,3354,287 -0.546410842239735,0.23036622014532987,2.032866242545018,0.23036622014532987,-0.9559681035265681,-0.1940306860173823,-1.3312935370263337,-0.8637791771530676,4.3750256940936305,-1.7657985305992057,-0.10770002139860704,-0.546410842239735,1.8948765913387664,2.664757267155283,3.713721512871941,0.31303318522898527,0.5964120554641071,-1.0488191777371687,-0.06480379588709152,-0.9559681035265681,1.7549981936289338,0.3540841185619894,0.14695211780225223,0.4760956266149155,1.1748381597601374,3.6248188309031892,0.8709321917690549,0.9478531474732188,0.7150999985878068,3.201023198065498,0.51638636702171,2.7291839700941773,0.4760956266149155,-0.1940306860173823,-0.36882191692968064,0.5964120554641071,-0.6362392226649662,-0.4572697498231123,-0.15077592925131486,0.06279828060143189,-0.022088097488964575,0.27179356591045745,0.4760956266149155,3.9186948792031995,0.909473770504105,-0.6362392226649662,0.51638636702171,0.9478531474732188,0.14695211780225223,-0.15077592925131486,-1.0488191777371687,-0.412958796825298,-1.0954913801193207,0.4760956266149155,-0.3248598804887178,1.4329258820598159,-0.3248598804887178,-0.8637791771530676,0.27179356591045745,0.5964120554641071,-1.0954913801193207,0.4356160170646649,1.5414559276361184,-2.6721680762670923,1.0620389315076852 3367 Developmental maturation 6 44 2.647575491337629 0.0081071256634208 O75503,Q15125,Q8N2A8,P05067,Q12768,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 3,7,142,14,121,162 183,2575,959,2064,629,3,1744,841,2430,14,3065,731,2248,1572,1990,1042,2164,1914,1049,2083,1325,1682,3245,1250,121,858,2526,2093,327,7,3102,1188,1067,916,557,142,614,399,998,1961,162,889,2943,2233 1.3231682601538646,-0.546410842239735,0.31303318522898527,-0.2810734678085235,0.5564909583357176,5.682423722639393,-0.10770002139860704,0.3949453920319386,-0.4572697498231123,4.815860976496678,-0.9559681035265681,0.4760956266149155,-0.36882191692968064,-0.022088097488964575,-0.23746346936348223,0.27179356591045745,-0.3248598804887178,-0.1940306860173823,0.27179356591045745,-0.2810734678085235,0.10496721166567786,-0.06480379588709152,-1.3312935370263337,0.14695211780225223,1.613148049789865,0.3949453920319386,-0.5017540153159744,-0.2810734678085235,0.9478531474732188,5.347423495313898,-1.0023112020703986,0.18875209347989597,0.27179356591045745,0.3540841185619894,0.6361522503407359,1.5054130123499248,0.5964120554641071,0.8322262551325478,0.31303318522898527,-0.1940306860173823,1.4329258820598159,0.3949453920319386,-0.7722577547913748,-0.3248598804887178 3367 Lipid localization 13 76 2.6378062569999776 0.0083444240317147 Q07954,P29375,Q99720,P07686,Q8WTV0,P17900,P07602,O15260,O15118,Q9BUR5,P61916,Q14108,P14174 Processes and pathways GO Biological process msigdb_gobp 120,69,37,103,110,46,17,49,81,85,25,27,116 1898,1163,1298,81,49,1561,1373,1303,3235,633,1663,411,2794,2655,841,2155,2986,17,103,1310,3340,466,116,46,1110,2993,2437,258,69,290,1477,2995,361,635,2002,1393,25,603,1686,2268,2815,120,645,27,1857,370,3196,690,1696,1346,3219,3330,110,2763,2765,758,37,2887,2626,85,1884,1533,2560,571,1358,826,2219,162,2412,708,831,1014,2320,3170,3059,1224 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3367 Abnormal vertebral morphology 20 110 2.63440384925867 0.0084285171899123 Q9UBM7,Q99575,P04066,Q15125,P15586,Q14108,Q14739,P16278,O00754,Q9NUQ7,Q8NCM8,P51798,P54802,P10619,Q8IWS0,Q96HA7,Q9NZC9,O00170,Q12768,Q8IY37 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,266,6,7,13,27,38,164,44,315,181,307,54,68,332,349,97,337,121,251 3089,337,1225,44,497,840,3211,2576,1104,895,2064,960,1902,1167,3238,3278,1743,2068,1377,841,6,1037,68,1748,2904,13,164,2991,732,2348,1109,3241,1043,2165,1580,2082,1581,3314,3095,906,3257,2360,307,3352,54,2520,1846,2599,1683,2089,3180,3000,1183,682,1772,121,1774,1119,2376,27,38,1690,3302,7,1780,1497,2024,371,521,2533,2534,2753,2606,2822,2281,1949,1343,332,251,811,181,2471,1624,2038,349,1523,1353,927,996,266,2629,1889,2308,2484,3085,315,765,97,1,3022,2637,2980,710,889,2982,662,3117,2642,774,2418 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3367 Terpenoid metabolic process 6 15 2.631842435419874 0.0084923237618697 P29375,Q8TC12,Q9HB40,Q6NUM9,Q07954,P37268 Processes and pathways GO Biological process msigdb_gobp 69,172,9,76,120,30 2147,1909,2731,1990,69,30,215,2596,3339,120,76,878,172,9,1093 -0.3248598804887178,-0.1940306860173823,-0.6362392226649662,-0.23746346936348223,2.1690444425785262,3.4751842548839553,1.212138715175788,-0.546410842239735,-2.3139063625418146,1.613148049789865,2.0670777141599412,0.3949453920319386,1.3964785412072227,5.321323717121585,0.27179356591045745 3367 Intrinsic component of organelle membrane 16 111 2.631051735942774 0.008512107689794 Q9UBM7,P10321,Q9NZ01,Q14739,Q15125,Q5J8M3,P04439,P42892,O15118,L0R6Q1,P01889,Q9BUR5,Q9H490,P13473,Q9HC21,O96008 Localization GO Cellular component msigdb_gocc 1,213,336,38,7,170,73,16,81,83,84,85,284,26,192,271 1898,83,954,583,1298,81,1371,1558,537,2146,1373,1901,1165,1980,1904,2151,2792,3033,2653,963,668,462,271,84,73,213,1040,26,2435,2436,2800,846,2735,3314,16,1393,908,2086,973,1053,679,739,912,1935,1403,2378,38,861,519,686,7,2189,1606,1407,2277,2460,170,2462,868,1786,1506,870,750,3011,1346,1951,2111,1701,1620,2542,1872,561,1954,485,1955,1517,2930,2041,1528,3290,2769,2626,2209,335,85,1003,1287,284,2212,3052,192,764,384,3166,574,2780,1647,336,767,1011,1,622,1544,3086,1445,2323,3192,774,2493,836,1224 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3367 Increased head circumference 39 133 2.63073960943758 0.0085199286803969 Q15392,Q07864,Q99575,O14802,O14646,Q9HCK8,P07602,P53007,Q9NZJ7,P41229,Q14739,O00754,Q8NCM8,Q93008,O43505,P51798,Q14118,Q8IWS0,Q14839,Q7Z6Z7,Q8IYB7,Q8WVX9,Q9BU61,Q9NR50,Q96HA7,P11310,P11166,O43933,P19022,O75970,P42858,O75962,P07686,P42345,P49770,P10412,Q12768,Q2M1P5,Q96HP0 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,367,266,497,132,402,17,510,162,33,38,44,181,311,537,307,327,332,199,610,611,485,351,492,349,91,466,96,214,340,100,358,103,107,470,112,121,371,253 2235,44,132,497,1555,1099,3211,537,96,2064,1823,1902,2789,629,1305,2985,1031,725,1904,358,340,1462,3255,3148,17,103,2727,2340,112,466,91,2905,732,214,2349,1754,3225,3066,2954,33,107,100,793,2003,470,2360,1585,1325,1928,2363,307,3352,510,2916,1930,972,973,2742,1245,1765,978,742,2920,2182,367,1772,121,2963,797,2868,913,2376,1334,799,1251,327,605,1060,1406,2457,38,199,2529,1692,0,1497,1860,1407,1189,371,1194,2753,1342,610,332,611,811,2468,181,2296,485,1956,2202,311,1877,1517,349,253,1353,996,1637,2208,266,1281,351,2629,822,1534,2211,2776,3052,402,492,1437,2410,162,3022,3167,1725,889,1015,1652,2646 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3367 Disinhibition 18 56 2.610864890428239 0.0090313566823596 Q9NZ01,Q709C8,P19022,P42858,Q04637,P17480,Q6P1N0,Q96N66,Q9NUQ7,Q96F07,P05067,Q13501,P49815,Q9ULK4,Q2M389,P26358,O75165,O96008 Drugs and Diseases Human Phenotype Ontology msigdb_hp 336,200,214,100,515,439,376,144,315,111,14,234,546,355,52,176,300,271 1227,300,271,841,14,1991,439,214,1384,176,1319,3177,100,2913,2740,546,2916,2262,2741,796,978,515,2813,2182,2744,1250,2453,1490,234,1776,1604,1692,52,376,2190,919,1865,200,609,2293,993,1877,1275,111,1798,144,1074,816,2207,2480,1281,2403,315,336,3055,355 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3367 Nonimmune hydrops fetalis 9 29 2.6058807459269007 0.009163836104435 P10619,Q14739,Q07020,P62899,P61313,P62847,P18077,P42766,P61353 Drugs and Diseases Human Phenotype Ontology msigdb_hp 68,38,134,198,74,197,165,177,275 1560,1459,2654,841,1378,1230,68,165,3095,177,292,3227,851,910,74,275,1054,680,855,197,1681,198,2264,134,38,924,1530,3291,1719 -0.022088097488964575,0.020446217421404334,-0.5912394888767456,0.3949453920319386,0.06279828060143189,0.14695211780225223,2.1690444425785262,1.3964785412072227,-1.0023112020703986,1.3598932144259221,1.0241336866990407,-1.2838097038521317,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,1.5414559276361184,3.1701628794451158,0.3540841185619894,0.020446217421404334,-1.52282763066264,-0.06480379588709152 3367 Aggressive behavior 7 89 2.602942145012719 0.0092427549542506 Q9UBM7,P41229,O75503,Q15125,O00462,P54802,Q8WYQ5 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,33,3,7,40,54,87 2235,40,2497,2573,1099,3,358,466,439,1384,1670,2258,1474,2439,2509,1914,1388,3128,33,100,2740,546,599,2086,1325,3270,2005,1588,54,2262,1591,972,978,1183,3130,2813,2182,1772,2963,797,2868,2092,234,1251,1254,1060,2457,7,1692,2024,1260,3246,2028,2280,1864,1865,609,1197,1866,2293,2197,993,87,2549,311,1877,2550,925,1350,1799,996,1637,816,930,2207,1714,1281,2629,2403,426,2776,3082,1896,1,3167,3023,2567,889,2717 -0.36882191692968064,3.1081955602316613,-0.5017540153159744,-0.546410842239735,0.23036622014532987,5.682423722639393,0.8709321917690549,0.7150999985878068,0.754312439228042,0.06279828060143189,-0.06480379588709152,-0.36882191692968064,0.020446217421404334,-0.4572697498231123,-0.5017540153159744,-0.1940306860173823,0.06279828060143189,-1.0488191777371687,3.3236578103542245,1.7549981936289338,-0.6362392226649662,0.6361522503407359,0.5964120554641071,-0.2810734678085235,0.10496721166567786,-1.426742025084107,-0.23746346936348223,-0.022088097488964575,2.664757267155283,-0.36882191692968064,-0.022088097488964575,0.31303318522898527,0.31303318522898527,0.18875209347989597,-1.0488191777371687,-0.6814093200124656,-0.3248598804887178,-0.10770002139860704,-0.8179346882917339,0.4356160170646649,-0.7267490661171271,-0.2810734678085235,1.1748381597601374,0.14695211780225223,0.14695211780225223,0.27179356591045745,-0.4572697498231123,5.347423495313898,-0.06480379588709152,-0.23746346936348223,0.14695211780225223,-1.3312935370263337,-0.23746346936348223,-0.36882191692968064,-0.15077592925131486,-0.15077592925131486,0.5964120554641071,0.18875209347989597,-0.15077592925131486,-0.36882191692968064,-0.3248598804887178,0.31303318522898527,1.9641025522127773,-0.5017540153159744,0.9860724317343753,-0.15077592925131486,-0.5017540153159744,0.3540841185619894,0.10496721166567786,-0.10770002139860704,0.31303318522898527,-0.022088097488964575,0.4356160170646649,0.3540841185619894,-0.3248598804887178,-0.06480379588709152,0.14695211780225223,-0.546410842239735,-0.412958796825298,0.7933537558921767,-0.6362392226649662,-0.9559681035265681,-0.15077592925131486,6.354521266861696,-1.0954913801193207,-0.8637791771530676,-0.5017540153159744,0.3949453920319386,-0.5912394888767456 3367 Cellular lipid catabolic process 11 62 2.601175360067973 0.0092904950334826 P50897,P04066,P07686,Q13510,P17900,Q8NHP8,P06865,Q2T9J0,P06280,P11310,Q8NCC3 Processes and pathways GO Biological process msigdb_gobp 35,6,103,104,46,15,47,92,23,91,60 664,1163,1821,1298,1101,1373,3147,3278,668,2247,841,6,1035,965,23,47,103,3174,91,2905,46,1472,2993,2437,2799,2859,258,2802,1996,1477,361,2954,2354,1236,3069,2003,1393,35,2363,2176,2268,3365,104,2674,1407,2820,3216,92,1696,2610,1348,333,60,15,110,2202,1714,759,1002,3190,493,1546 0.51638636702171,0.18875209347989597,-0.15077592925131486,0.10496721166567786,0.23036622014532987,0.06279828060143189,-1.0954913801193207,-1.4747054833332776,0.51638636702171,-0.36882191692968064,0.3949453920319386,5.477203395245907,0.27179356591045745,0.31303318522898527,3.860476447122193,2.9518057266228475,1.719723884747831,-1.142327166182432,1.8948765913387664,-0.7722577547913748,3.014617485988229,0.020446217421404334,-0.8637791771530676,-0.4572697498231123,-0.6814093200124656,-0.7267490661171271,1.099790142352336,-0.6814093200124656,-0.23746346936348223,0.020446217421404334,0.8709321917690549,-0.8179346882917339,-0.412958796825298,0.14695211780225223,-0.9559681035265681,-0.23746346936348223,0.06279828060143189,3.2625005214835268,-0.412958796825298,-0.3248598804887178,-0.36882191692968064,-8.898651371343082,1.719723884747831,-0.5912394888767456,0.06279828060143189,-0.6814093200124656,-1.2364869532593843,1.8948765913387664,-0.06480379588709152,-0.546410842239735,0.10496721166567786,0.9478531474732188,2.3368292667835435,4.815860976496678,1.6843250163853651,-0.3248598804887178,-0.06480379588709152,0.4760956266149155,0.31303318522898527,-1.142327166182432,0.7150999985878068,0.020446217421404334 3367 Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 6 12 2.597961084328912 0.0093779121400443 Q15392,Q9UBM7,Q14739,Q8N4Q0,P30043,Q14914 Functions GO Molecular function msigdb_gomf 0,1,38,12,228,329 228,3152,597,2173,38,329,0,12,3320,3142,336,1 1.1748381597601374,-1.0954913801193207,0.5964120554641071,-0.3248598804887178,3.1701628794451158,0.9478531474732188,9.266342596549883,5.110752473018885,-1.8148607923698326,-1.0488191777371687,0.9478531474732188,6.354521266861696 3367 Neuron apoptotic process 11 50 2.597846780778731 0.0093810342650439 P50897,O95630,Q99720,P04179,P42574,P05067,P48507,Q99538,Q9H2P0,Q92542,O14786 Processes and pathways GO Biological process msigdb_gobp 35,437,37,464,260,14,417,20,426,159,127 626,127,1105,1376,2792,437,2068,841,464,1568,2582,14,3065,2157,2071,1908,503,1572,1477,1914,260,1917,1919,2444,1320,417,2357,597,2913,35,1325,1586,1117,1592,1330,3154,2091,1402,1692,159,1517,1628,3321,2480,20,37,426,2128,1650,952 0.5564909583357176,1.5773671103553362,0.23036622014532987,0.06279828060143189,-0.6814093200124656,0.754312439228042,-0.2810734678085235,0.3949453920319386,0.7150999985878068,-0.022088097488964575,-0.546410842239735,4.815860976496678,-0.9559681035265681,-0.3248598804887178,-0.2810734678085235,-0.1940306860173823,0.6757140740040977,-0.022088097488964575,0.020446217421404334,-0.1940306860173823,1.099790142352336,-0.1940306860173823,-0.1940306860173823,-0.4572697498231123,0.10496721166567786,0.7933537558921767,-0.412958796825298,0.5964120554641071,-0.7722577547913748,3.2625005214835268,0.10496721166567786,-0.022088097488964575,0.23036622014532987,-0.022088097488964575,0.10496721166567786,-1.0954913801193207,-0.2810734678085235,0.06279828060143189,-0.06480379588709152,1.4329258820598159,0.020446217421404334,-0.022088097488964575,-1.8148607923698326,-0.4572697498231123,3.9186948792031995,3.201023198065498,0.7933537558921767,-0.2810734678085235,-0.022088097488964575,0.3540841185619894 3367 Viral myocarditis 8 12 2.59464211168056 0.009468945939407 P10321,Q04637,P04439,P42574,P01889,P35580,Q14118,P35579 Processes and pathways KEGG Pathways msigdb_kegg 213,515,73,260,84,387,327,245 584,84,73,213,245,387,260,1245,976,515,327,2191 0.5964120554641071,1.9985415804284918,2.1011771507196184,1.212138715175788,1.1373892537486945,0.8322262551325478,1.099790142352336,0.14695211780225223,0.31303318522898527,0.6757140740040977,0.9478531474732188,-0.3248598804887178 3367 Tertiary granule 10 42 2.5925535738998406 0.0095266342334532 Q7L576,Q9Y2Q5,P11279,Q13510,Q92820,P63167,P13473,P10253,P27105,P42785 Localization GO Cellular component msigdb_gocc 263,136,90,104,77,277,26,59,62,31 2330,1103,1738,3278,786,1463,3149,2854,2505,59,90,26,2588,2345,62,2443,2738,31,2365,1243,2960,1245,277,2670,104,800,420,309,1947,690,263,1510,1624,77,923,1878,2301,1881,2313,3024,136,2647 -0.412958796825298,0.23036622014532987,-0.10770002139860704,-1.4747054833332776,0.4356160170646649,0.020446217421404334,-1.0954913801193207,-0.7267490661171271,-0.5017540153159744,2.4362503004565204,1.8948765913387664,3.713721512871941,-0.546410842239735,-0.412958796825298,2.270032897213297,-0.4572697498231123,-0.6362392226649662,3.4450326941058216,-0.412958796825298,0.14695211780225223,-0.8179346882917339,0.14695211780225223,1.0620389315076852,-0.5912394888767456,1.719723884747831,0.4356160170646649,0.7933537558921767,0.9860724317343753,-0.1940306860173823,0.51638636702171,1.099790142352336,0.020446217421404334,-0.022088097488964575,2.0670777141599412,0.3540841185619894,-0.15077592925131486,-0.36882191692968064,-0.15077592925131486,-0.36882191692968064,-0.8637791771530676,1.5414559276361184,-0.546410842239735 3367 CD markers 8 15 2.587722756412313 0.009661270568013 P19022,P02786,P11279,P35613,P11717,Q07954,P13473,O14786 Functions Protein Atlas Protein class protein_atlas_protein_class 214,67,90,305,53,120,26,127 127,2243,67,1309,3340,1464,90,53,26,214,305,342,511,120,775 1.5773671103553362,-0.36882191692968064,2.202814512277326,0.10496721166567786,-2.3646418191340213,0.020446217421404334,1.8948765913387664,2.664757267155283,3.713721512871941,1.212138715175788,0.9860724317343753,0.909473770504105,0.6757140740040977,1.613148049789865,0.4760956266149155 3367 Agitation 8 33 2.5855225339685552 0.0097231516917775 P48449,Q709C8,P42858,Q13501,P05067,P42892,O75165,O96008 Drugs and Diseases Human Phenotype Ontology msigdb_hp 215,200,100,234,14,16,300,271 300,2725,271,841,14,731,2072,1748,2799,361,1319,100,16,1918,215,3305,1325,2005,2262,978,515,1490,234,1604,1406,2188,2756,919,200,1423,1074,2480,1714 0.9860724317343753,-0.6362392226649662,1.0620389315076852,0.3949453920319386,4.815860976496678,0.4760956266149155,-0.2810734678085235,-0.10770002139860704,-0.6814093200124656,0.8709321917690549,0.10496721166567786,1.7549981936289338,4.4588127644301565,-0.1940306860173823,1.212138715175788,-1.6681404132370228,0.10496721166567786,-0.23746346936348223,-0.36882191692968064,0.31303318522898527,0.6757140740040977,0.020446217421404334,1.1748381597601374,-0.022088097488964575,0.06279828060143189,-0.3248598804887178,-0.6362392226649662,0.3540841185619894,1.2863020037686608,0.06279828060143189,0.27179356591045745,-0.4572697498231123,-0.06480379588709152 3367 Leishmania infection 10 39 2.5808268553348217 0.0098564002219863 Q7L576,O15143,Q14185,Q13459,Q12965,Q96F07,P05067,Q9Y4I1,Q9UQB8,P35579 Processes and pathways Reactome Pathways msigdb_reactome 263,338,101,262,261,111,14,287,29,245 407,1369,338,2786,2143,900,14,2071,2340,1908,1748,2730,1472,3126,1670,245,2263,1117,3097,2370,1055,2012,1245,1483,2962,261,262,101,2025,263,2037,111,1278,2225,29,661,2231,949,287 0.7933537558921767,0.06279828060143189,0.909473770504105,-0.6814093200124656,-0.3248598804887178,0.3540841185619894,4.815860976496678,-0.2810734678085235,-0.412958796825298,-0.1940306860173823,-0.10770002139860704,-0.6362392226649662,0.020446217421404334,-1.0488191777371687,-0.06480379588709152,1.1373892537486945,-0.36882191692968064,0.23036622014532987,-1.0023112020703986,-0.412958796825298,0.27179356591045745,-0.23746346936348223,0.14695211780225223,0.020446217421404334,-0.8179346882917339,1.099790142352336,1.099790142352336,1.7549981936289338,-0.23746346936348223,1.099790142352336,-0.23746346936348223,1.6843250163853651,0.14695211780225223,-0.3248598804887178,3.535260987655072,0.5564909583357176,-0.3248598804887178,0.3540841185619894,1.0620389315076852 3367 Lipid metabolism 16 127 2.576041106324857 0.0099938764431799 Q15392,Q9UBM7,Q14739,Q15125,Q13510,Q8N2A8,Q96N66,Q96G23,Q8NHP8,P17900,P07602,O15118,P61916,P11310,Q8NCC3,P37268 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 0,1,38,7,104,142,144,143,15,46,17,81,25,91,60,30 664,2060,2495,1163,954,1821,1452,1298,81,1101,1025,1659,1823,2499,2501,668,1663,411,2247,463,2070,841,1035,17,3174,2854,91,467,2731,46,1472,1832,2437,2799,2859,3333,2802,1996,2995,1579,361,635,30,2000,2168,2354,1236,3069,415,3152,215,793,597,2003,1393,908,2596,2363,1114,1762,1679,2176,2807,25,1329,2090,1686,3339,1185,3131,3365,1118,645,104,1602,1122,1252,38,329,2674,520,7,3075,984,0,2024,446,3216,157,986,688,1193,1696,557,2610,142,1348,1269,60,2758,15,3249,485,223,3322,143,144,3050,2767,1714,759,881,1639,1962,826,3142,3083,2312,336,767,1,622,831,2713,1546,534,2141 0.51638636702171,-0.2810734678085235,-0.5017540153159744,0.18875209347989597,0.31303318522898527,-0.15077592925131486,0.020446217421404334,0.10496721166567786,2.032866242545018,0.23036622014532987,0.27179356591045745,-0.06480379588709152,-0.15077592925131486,-0.5017540153159744,-0.5017540153159744,0.51638636702171,-0.06480379588709152,0.7933537558921767,-0.36882191692968064,0.7150999985878068,-0.2810734678085235,0.3949453920319386,0.27179356591045745,4.3750256940936305,-1.142327166182432,-0.7267490661171271,1.8948765913387664,0.7150999985878068,-0.6362392226649662,3.014617485988229,0.020446217421404334,-0.15077592925131486,-0.4572697498231123,-0.6814093200124656,-0.7267490661171271,-2.1124650811200967,-0.6814093200124656,-0.23746346936348223,-0.8637791771530676,-0.022088097488964575,0.8709321917690549,0.5564909583357176,3.4751842548839553,-0.23746346936348223,-0.3248598804887178,-0.412958796825298,0.14695211780225223,-0.9559681035265681,0.7933537558921767,-1.0954913801193207,1.212138715175788,0.4356160170646649,0.5964120554641071,-0.23746346936348223,0.06279828060143189,0.3540841185619894,-0.546410842239735,-0.412958796825298,0.23036622014532987,-0.10770002139860704,-0.06480379588709152,-0.3248598804887178,-0.6814093200124656,3.772633277255873,0.10496721166567786,-0.2810734678085235,-0.06480379588709152,-2.3139063625418146,0.18875209347989597,-1.0488191777371687,-8.898651371343082,0.23036622014532987,0.5564909583357176,1.719723884747831,-0.022088097488964575,0.23036622014532987,0.14695211780225223,3.1701628794451158,0.9478531474732188,-0.5912394888767456,0.6757140740040977,5.347423495313898,-0.9559681035265681,0.31303318522898527,9.266342596549883,-0.23746346936348223,0.754312439228042,-1.2364869532593843,1.4329258820598159,0.31303318522898527,0.51638636702171,0.18875209347989597,-0.06480379588709152,0.6361522503407359,-0.546410842239735,1.5054130123499248,0.10496721166567786,0.14695211780225223,2.3368292667835435,-0.6362392226649662,4.815860976496678,-1.3312935370263337,0.7150999985878068,1.212138715175788,-1.8148607923698326,1.5054130123499248,1.5054130123499248,-0.9097905400273109,-0.6362392226649662,-0.06480379588709152,0.4760956266149155,0.3949453920319386,-0.022088097488964575,-0.1940306860173823,0.4356160170646649,-1.0488191777371687,-0.9559681035265681,-0.36882191692968064,0.9478531474732188,0.4760956266149155,6.354521266861696,0.5964120554641071,0.4356160170646649,-0.5912394888767456,0.020446217421404334,0.6757140740040977,-0.2810734678085235 3367 Abnormal autonomic nervous system physiology 7 37 2.573432651839548 0.0100695242477335 P35251,P07686,Q99996,P42892,P07602,P06280,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 153,103,79,16,17,23,162 497,1301,1029,300,2792,2337,841,23,17,103,413,3240,153,2355,16,3178,1325,2091,515,2182,1334,2674,2756,919,200,876,1277,1074,816,2480,79,2774,1722,162,950,2717,837 0.6757140740040977,0.10496721166567786,0.27179356591045745,0.9860724317343753,-0.6814093200124656,-0.412958796825298,0.3949453920319386,3.860476447122193,4.3750256940936305,1.719723884747831,0.7933537558921767,-1.3312935370263337,1.4329258820598159,-0.412958796825298,4.4588127644301565,-1.142327166182432,0.10496721166567786,-0.2810734678085235,0.6757140740040977,-0.3248598804887178,0.10496721166567786,-0.5912394888767456,-0.6362392226649662,0.3540841185619894,1.2863020037686608,0.3949453920319386,0.14695211780225223,0.27179356591045745,0.4356160170646649,-0.4572697498231123,2.0670777141599412,-0.6362392226649662,-0.06480379588709152,1.4329258820598159,0.3540841185619894,-0.5912394888767456,0.4356160170646649 3367 Diseases of metabolism 15 44 2.567626636523926 0.0102397379943532 Q2TAA5,P10619,P07686,Q14118,P16278,P11498,P15586,P06865,Q96RQ3,P48507,O43505,P54802,P10253,P50747,O75352 Processes and pathways Reactome Pathways msigdb_reactome 169,68,103,327,164,467,13,47,312,417,537,54,59,547,184 537,2651,3277,184,3278,1035,965,47,103,59,68,467,1910,13,164,1575,1832,1177,3038,2738,2259,596,1320,417,3228,547,1482,1324,54,2091,1599,1118,1494,327,169,2689,1351,927,312,1141,1530,2127,2490,2897 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Q15392,Q15125,P07602,Q9H490,P06280,Q14108,Q9NZJ7,Q14739,P16278,O00754,Q9NUQ7,Q93008,P51798,P54802,O75531,Q9HC21,Q15043,P27635,Q96HA7,Q14692,Q9NZC9,O00170,Q13510,Q13501,Q9H9Y6,Q8IY37 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,7,17,284,23,27,162,38,164,44,315,311,307,54,301,192,330,195,349,346,97,337,104,234,383,251 3089,337,1225,44,433,497,2984,840,2331,2787,2576,1104,960,1228,1980,1031,301,3238,1904,1743,2903,2068,1377,3148,841,1035,965,1378,23,1169,3193,1037,17,1748,1040,790,2904,164,1174,1042,671,1109,2949,1994,195,1234,2165,1914,1580,2000,3067,636,2513,793,2360,2363,307,2999,2864,54,1589,2262,602,2520,1846,2599,2264,2089,3180,1183,742,682,367,2524,1600,1400,1119,1120,234,104,27,1856,346,38,802,1779,330,3302,7,2096,0,1497,2750,521,2533,2534,1408,3247,1949,251,1624,993,1205,311,1517,2038,349,1523,927,1075,530,821,569,2308,1717,284,2936,383,192,1361,2563,3085,315,765,2134,97,162,3209,710,3192,2642,1295,774,837,3027 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3367 Abnormal oral mucosa morphology 12 68 2.561463805542308 0.0104232101477546 Q15392,Q9UBM7,Q9H7D7,Q14739,Q13155,P16278,O00754,Q93008,P78527,P01889,Q14108,P53634 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,1,268,38,325,164,44,311,113,84,27,274 3089,408,44,1104,1228,2652,1980,1565,2903,84,841,3193,1748,2588,164,3240,2348,1580,636,1049,509,597,546,2362,274,1846,2089,113,1183,1184,1185,2962,2268,2524,325,2376,1058,27,38,606,3302,2096,0,371,2533,2534,2753,1409,3248,1864,1949,2542,1203,2300,311,1278,2041,530,268,1361,2134,944,1,710,2642,952,774,2897 -1.0023112020703986,0.7933537558921767,3.014617485988229,0.23036622014532987,0.14695211780225223,-0.5912394888767456,-0.23746346936348223,-0.022088097488964575,-0.7722577547913748,1.9985415804284918,0.3949453920319386,-1.1893259001279373,-0.10770002139860704,-0.546410842239735,1.3964785412072227,-1.3312935370263337,-0.412958796825298,-0.022088097488964575,0.5564909583357176,0.27179356591045745,0.6757140740040977,0.5964120554641071,0.6361522503407359,-0.412958796825298,1.0620389315076852,-0.15077592925131486,-0.2810734678085235,1.6488002071649115,0.18875209347989597,0.18875209347989597,0.18875209347989597,-0.8179346882917339,-0.36882191692968064,-0.5017540153159744,0.9478531474732188,-0.412958796825298,0.27179356591045745,3.6248188309031892,3.1701628794451158,0.5964120554641071,-1.6195456688999854,-0.2810734678085235,9.266342596549883,0.8709321917690549,-0.5017540153159744,-0.5017540153159744,-0.6362392226649662,0.06279828060143189,-1.3312935370263337,-0.15077592925131486,-0.1940306860173823,-0.5017540153159744,0.18875209347989597,-0.36882191692968064,0.9860724317343753,0.14695211780225223,-0.23746346936348223,0.6757140740040977,1.099790142352336,0.10496721166567786,-0.2810734678085235,0.3540841185619894,6.354521266861696,0.51638636702171,-0.546410842239735,0.3540841185619894,0.4760956266149155,-0.7267490661171271 3367 Abnormal form of the vertebral bodies 15 86 2.56097044441555 0.0104380235679168 Q9UBM7,Q9NZC9,Q99575,Q14739,P04066,Q15125,P16278,O00754,P15586,Q9NUQ7,Q12768,Q8IY37,P54802,P51798,Q96HA7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,97,266,38,6,7,164,44,13,315,121,251,54,307,349 3089,337,1225,44,497,840,3211,2576,1104,895,960,1902,1167,3278,1743,2068,1377,6,1037,1748,13,164,2991,732,2348,1109,3241,1043,2165,1580,2082,1581,3314,3095,906,3257,2360,307,3352,54,1846,1683,2089,3000,1183,682,1772,121,1774,1119,2376,38,1690,3302,7,1780,1497,521,2533,2534,2606,2822,1343,251,811,1624,2038,349,1523,1353,927,266,1889,2308,2484,315,97,1,3022,2980,710,2982,662,3117,2642,774 -1.0023112020703986,0.909473770504105,0.14695211780225223,3.014617485988229,0.6757140740040977,0.3949453920319386,-1.2364869532593843,-0.546410842239735,0.23036622014532987,0.3540841185619894,0.31303318522898527,-0.1940306860173823,0.18875209347989597,-1.4747054833332776,-0.10770002139860704,-0.2810734678085235,0.06279828060143189,5.477203395245907,0.27179356591045745,-0.10770002139860704,4.896921049154351,1.3964785412072227,-0.8637791771530676,0.4760956266149155,-0.412958796825298,0.23036622014532987,-1.3312935370263337,0.27179356591045745,-0.3248598804887178,-0.022088097488964575,-0.2810734678085235,-0.022088097488964575,-1.7657985305992057,-1.0023112020703986,0.3540841185619894,-1.378937844623164,-0.412958796825298,0.9860724317343753,-2.6721680762670923,2.664757267155283,-0.15077592925131486,-0.06480379588709152,-0.2810734678085235,-0.8637791771530676,0.18875209347989597,0.51638636702171,-0.10770002139860704,1.613148049789865,-0.10770002139860704,0.23036622014532987,-0.412958796825298,3.1701628794451158,-0.06480379588709152,-1.6195456688999854,5.347423495313898,-0.10770002139860704,0.020446217421404334,0.6757140740040977,-0.5017540153159744,-0.5017540153159744,-0.546410842239735,-0.6814093200124656,0.10496721166567786,1.1373892537486945,0.4356160170646649,-0.022088097488964575,-0.23746346936348223,0.909473770504105,0.020446217421404334,0.10496721166567786,0.3540841185619894,1.099790142352336,-0.15077592925131486,-0.36882191692968064,-0.4572697498231123,0.9860724317343753,1.8251785328251016,6.354521266861696,-0.8637791771530676,-0.8179346882917339,0.51638636702171,-0.8179346882917339,0.5564909583357176,-1.0023112020703986,-0.546410842239735,0.4760956266149155 3367 Diarrhea 9 73 2.547973623648068 0.0108350662947029 P02786,P07686,P15586,P42892,Q15904,P01889,P54802,P06280,P11310 Drugs and Diseases Human Phenotype Ontology msigdb_hp 67,103,13,16,48,84,54,23,91 1029,2651,2722,2652,2337,2247,728,84,67,2582,23,103,2853,1465,91,13,1042,732,2949,2799,1474,3038,361,3039,1999,2000,2168,2354,2513,3315,16,906,1393,735,2362,54,1843,1846,1184,1185,1250,391,2376,104,1058,1940,2273,2457,2096,2459,48,3216,688,2104,377,200,1949,3182,2926,1625,1205,1877,754,1517,2930,1353,2480,2704,1530,1717,2567,2942,952 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3367 Endoribonuclease activity 8 28 2.54303002961094 0.0109895783832079 Q9BSV6,Q99575,Q9ULX3,Q9BRJ7,Q8N2A8,O00584,P27695,Q96DE0 Functions GO Molecular function msigdb_gomf 334,266,72,106,142,18,304,28 18,1557,3173,587,667,540,304,1180,909,322,1596,1129,2687,1267,142,28,1798,266,1282,1529,106,334,1152,2414,72,1015,3233,3026 4.120355977593298,-0.022088097488964575,-1.142327166182432,0.5964120554641071,0.51638636702171,0.6361522503407359,0.9860724317343753,0.18875209347989597,0.3540841185619894,0.9478531474732188,-0.022088097488964575,0.23036622014532987,-0.5912394888767456,0.14695211780225223,1.5054130123499248,3.535260987655072,-0.10770002139860704,1.099790142352336,0.14695211780225223,0.020446217421404334,1.719723884747831,0.9478531474732188,0.23036622014532987,-0.412958796825298,2.1351656880009666,0.31303318522898527,-1.2838097038521317,-0.8637791771530676 3367 Coarctation of aorta 11 41 2.54285243723038 0.0109951652829396 Q9UBM7,P19022,Q9Y4A5,Q07020,Q14839,P62899,P61313,P62847,P18077,P42766,P61353 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,214,174,134,199,198,74,197,165,177,275 2719,1226,2788,1230,165,214,2259,3095,177,292,3227,1588,1930,851,910,74,275,1054,2742,680,855,197,1681,198,2264,742,2815,134,2376,199,1188,2924,1865,811,924,3082,1,2980,624,174,2418 -0.6362392226649662,0.14695211780225223,-0.6814093200124656,0.14695211780225223,1.3964785412072227,1.212138715175788,-0.36882191692968064,-1.0023112020703986,1.3598932144259221,1.0241336866990407,-1.2838097038521317,-0.022088097488964575,-0.1940306860173823,0.3949453920319386,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,-0.6362392226649662,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,0.4760956266149155,-0.6814093200124656,1.5414559276361184,-0.412958796825298,1.2863020037686608,0.18875209347989597,-0.7722577547913748,-0.15077592925131486,0.4356160170646649,0.3540841185619894,-0.9559681035265681,6.354521266861696,-0.8179346882917339,0.5964120554641071,1.3964785412072227,-0.412958796825298 3367 Memory impairment 15 42 2.5424102697802757 0.0110090864466136 P42858,P15289,Q13501,P05067,Q8WVX9,P07602,P49770,P40692,P01889,P26358,Q9NZJ7,Q9NR50,Q14232,O96008,P52701 Drugs and Diseases Human Phenotype Ontology msigdb_hp 100,413,234,14,485,17,470,469,84,176,162,492,605,271,548 1301,271,728,84,14,17,2853,413,176,1997,469,100,1919,597,470,548,1841,2366,1589,2262,851,2182,2963,913,234,605,2531,688,1203,485,2550,1075,1280,492,944,162,1725,2567,2894,2490,2897,2493 0.10496721166567786,1.0620389315076852,0.4760956266149155,1.9985415804284918,4.815860976496678,4.3750256940936305,-0.7267490661171271,0.7933537558921767,1.3598932144259221,-0.23746346936348223,0.7150999985878068,1.7549981936289338,-0.1940306860173823,0.5964120554641071,0.7150999985878068,0.6361522503407359,-0.15077592925131486,-0.412958796825298,-0.022088097488964575,-0.36882191692968064,0.3949453920319386,-0.3248598804887178,-0.8179346882917339,0.3540841185619894,1.1748381597601374,0.5964120554641071,-0.5017540153159744,0.51638636702171,0.18875209347989597,0.7150999985878068,-0.5017540153159744,0.27179356591045745,0.14695211780225223,0.7150999985878068,0.3540841185619894,1.4329258820598159,-0.06480379588709152,-0.5017540153159744,-0.7267490661171271,-0.4572697498231123,-0.7267490661171271,-0.4572697498231123 3367 Rigidity 12 53 2.541291844153569 0.0110443687959123 Q15392,Q709C8,P42858,P17480,P04350,P16278,P15289,Q96F07,Q9Y4I1,P07602,O75165,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 0,200,100,439,465,164,413,111,287,17,300,162 1974,1301,300,3173,1985,841,465,17,1040,413,164,439,2162,1478,1388,2861,3177,100,2913,1322,1325,2005,1590,2741,796,515,2813,2182,2744,1687,1604,0,2756,919,200,1792,2202,2206,1424,111,1074,1075,2480,2769,2049,162,2894,1220,950,2232,2717,287,2493 -0.23746346936348223,0.10496721166567786,0.9860724317343753,-1.142327166182432,-0.23746346936348223,0.3949453920319386,0.7150999985878068,4.3750256940936305,0.27179356591045745,0.7933537558921767,1.3964785412072227,0.754312439228042,-0.3248598804887178,0.020446217421404334,0.06279828060143189,-0.7267490661171271,-1.142327166182432,1.7549981936289338,-0.7722577547913748,0.10496721166567786,0.10496721166567786,-0.23746346936348223,-0.022088097488964575,-0.6362392226649662,0.4356160170646649,0.6757140740040977,-0.6814093200124656,-0.3248598804887178,-0.6362392226649662,-0.06480379588709152,-0.022088097488964575,9.266342596549883,-0.6362392226649662,0.3540841185619894,1.2863020037686608,-0.10770002139860704,-0.3248598804887178,-0.3248598804887178,0.06279828060143189,1.6843250163853651,0.27179356591045745,0.27179356591045745,-0.4572697498231123,-0.6362392226649662,-0.23746346936348223,1.4329258820598159,-0.7267490661171271,0.18875209347989597,0.3540841185619894,-0.3248598804887178,-0.5912394888767456,1.0620389315076852,-0.4572697498231123 3367 Myosin head, motor domain [IPR001609] 7 10 2.5356805128515845 0.0112229070754461 Q13459,Q12965,O94832,O43795,Q9Y4I1,P35580,P35579 Sequence InterPro Domain interpro_domain 262,261,319,206,287,387,245 407,206,319,245,387,261,262,2191,890,287 0.7933537558921767,1.249292736644776,0.9478531474732188,1.1373892537486945,0.8322262551325478,1.099790142352336,1.099790142352336,-0.3248598804887178,0.3949453920319386,1.0620389315076852 3367 Carboxylic acid transport 12 29 2.532302747660893 0.0113316105781275 P80404,O95563,P53985,P30825,P28288,P07602,Q15041,Q9H2D1,P14174,Q9UBX3,Q9NZJ7,O14745 Processes and pathways GO Biological process msigdb_gobp 65,462,294,259,258,17,519,490,116,495,162,433 433,2848,1984,2428,462,2155,1309,17,1464,116,258,259,2355,510,294,2916,65,1248,645,519,1779,2677,1696,490,2976,2212,162,495,2567 0.754312439228042,-0.7267490661171271,-0.23746346936348223,-0.4572697498231123,0.7150999985878068,-0.3248598804887178,0.10496721166567786,4.3750256940936305,0.020446217421404334,1.613148049789865,1.099790142352336,1.099790142352336,-0.412958796825298,0.6757140740040977,1.0241336866990407,-0.7722577547913748,2.2364769766120918,0.14695211780225223,0.5564909583357176,0.6757140740040977,-0.10770002139860704,-0.5912394888767456,-0.06480379588709152,0.7150999985878068,-0.8179346882917339,-0.3248598804887178,1.4329258820598159,0.7150999985878068,-0.5017540153159744 3367 Reduced consciousness confusion 33 133 2.529424097727031 0.0114249882606713 Q9UBM7,Q07020,P05067,P07602,Q13423,Q15833,P60891,P61353,Q9NZJ7,O96008,P21953,P46777,O00754,P18077,P15289,Q96RQ3,P42766,P26358,Q9Y3D3,Q86Y39,Q9HC21,P80404,P62899,P61313,P62847,Q9NPL8,P01889,Q9BU61,Q9NR50,P11310,P11166,P42858,P35610 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,134,14,17,391,420,24,275,162,271,152,292,44,165,413,312,177,176,455,190,192,65,198,74,197,80,84,351,492,91,466,100,361 1656,3267,44,497,628,1301,1561,1901,538,1903,2791,2654,271,2069,728,84,841,14,1035,965,17,2853,2987,1230,2248,466,3125,91,1040,2905,413,1042,165,2658,671,1176,152,1575,1384,2437,2799,176,2859,2438,1474,1477,1914,1388,361,3039,1999,1581,2954,3095,636,2354,3128,177,100,1839,3152,292,3227,597,2003,470,1322,3096,1393,547,2362,2176,851,24,910,74,275,1054,680,855,197,1681,198,2264,65,134,2524,2963,913,391,605,1406,420,1407,3216,1788,190,3105,811,1203,3219,1205,2202,924,2550,2206,1351,2623,312,1075,1280,2702,351,1080,2976,192,2127,80,492,2133,1966,944,162,2486,1,1725,2567,2640,455,2897,837,2140,838 -0.06480379588709152,-1.426742025084107,3.014617485988229,0.6757140740040977,0.5564909583357176,0.10496721166567786,-0.022088097488964575,-0.1940306860173823,0.6361522503407359,-0.1940306860173823,-0.6814093200124656,-0.5912394888767456,1.0620389315076852,-0.2810734678085235,0.4760956266149155,1.9985415804284918,0.3949453920319386,4.815860976496678,0.27179356591045745,0.31303318522898527,4.3750256940936305,-0.7267490661171271,-0.8637791771530676,0.14695211780225223,-0.36882191692968064,0.7150999985878068,-1.0488191777371687,1.8948765913387664,0.27179356591045745,-0.7722577547913748,0.7933537558921767,0.27179356591045745,1.3964785412072227,-0.5912394888767456,0.51638636702171,0.18875209347989597,1.4329258820598159,-0.022088097488964575,0.06279828060143189,-0.4572697498231123,-0.6814093200124656,1.3598932144259221,-0.7267490661171271,-0.4572697498231123,0.020446217421404334,0.020446217421404334,-0.1940306860173823,0.06279828060143189,0.8709321917690549,-0.9097905400273109,-0.23746346936348223,-0.022088097488964575,-0.8179346882917339,-1.0023112020703986,0.5564909583357176,-0.412958796825298,-1.0488191777371687,1.3598932144259221,1.7549981936289338,-0.15077592925131486,-1.0954913801193207,1.0241336866990407,-1.2838097038521317,0.5964120554641071,-0.23746346936348223,0.7150999985878068,0.10496721166567786,-1.0023112020703986,0.06279828060143189,0.6361522503407359,-0.412958796825298,-0.3248598804887178,0.3949453920319386,3.8312646321143324,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,2.2364769766120918,1.5414559276361184,-0.5017540153159744,-0.8179346882917339,0.3540841185619894,0.8322262551325478,0.5964120554641071,0.06279828060143189,0.7933537558921767,0.06279828060143189,-1.2364869532593843,-0.10770002139860704,1.3231682601538646,-1.0023112020703986,0.4356160170646649,0.18875209347989597,-1.2364869532593843,0.18875209347989597,-0.3248598804887178,0.3540841185619894,-0.5017540153159744,-0.3248598804887178,0.10496721166567786,-0.546410842239735,0.9860724317343753,0.27179356591045745,0.14695211780225223,-0.5912394888767456,0.909473770504105,0.27179356591045745,-0.8179346882917339,1.3231682601538646,-0.2810734678085235,2.0670777141599412,0.7150999985878068,-0.2810734678085235,-0.1940306860173823,0.3540841185619894,1.4329258820598159,-0.4572697498231123,6.354521266861696,-0.06480379588709152,-0.5017540153159744,-0.546410842239735,0.754312439228042,-0.7267490661171271,0.4356160170646649,-0.2810734678085235,0.4356160170646649 3367 Endonuclease activity 10 46 2.525304673372072 0.0115598022270111 O76075,Q9BSV6,Q99575,Q9ULX3,Q9BRJ7,Q8N2A8,P78345,O00584,P27695,Q96DE0 Functions GO Molecular function msigdb_gomf 128,334,266,72,106,142,322,18,304,28 18,1557,339,3173,587,667,128,540,1471,1833,304,1180,2446,909,2366,322,1596,1933,2869,1601,2531,1129,2687,1267,142,1708,1205,28,1798,1526,1076,266,1282,1529,106,2625,334,1147,1152,2414,72,1015,3233,891,3026,2785 4.120355977593298,-0.022088097488964575,0.909473770504105,-1.142327166182432,0.5964120554641071,0.51638636702171,1.5773671103553362,0.6361522503407359,0.020446217421404334,-0.15077592925131486,0.9860724317343753,0.18875209347989597,-0.4572697498231123,0.3540841185619894,-0.412958796825298,0.9478531474732188,-0.022088097488964575,-0.1940306860173823,-0.7267490661171271,-0.022088097488964575,-0.5017540153159744,0.23036622014532987,-0.5912394888767456,0.14695211780225223,1.5054130123499248,-0.06480379588709152,0.18875209347989597,3.535260987655072,-0.10770002139860704,0.020446217421404334,0.27179356591045745,1.099790142352336,0.14695211780225223,0.020446217421404334,1.719723884747831,-0.546410842239735,0.9478531474732188,0.23036622014532987,0.23036622014532987,-0.412958796825298,2.1351656880009666,0.31303318522898527,-1.2838097038521317,0.3949453920319386,-0.8637791771530676,-0.6362392226649662 3367 Abnormal erythrocyte enzyme level 8 21 2.5237306961992965 0.011611684405931 Q07020,P62899,P61313,P62847,P18077,P42766,P60891,P61353 Drugs and Diseases Human Phenotype Ontology msigdb_hp 134,198,74,197,165,177,24,275 1230,165,3095,177,292,3227,851,24,910,74,275,1054,680,855,197,1681,198,2264,134,924,816 0.14695211780225223,1.3964785412072227,-1.0023112020703986,1.3598932144259221,1.0241336866990407,-1.2838097038521317,0.3949453920319386,3.8312646321143324,0.3540841185619894,2.0670777141599412,1.0620389315076852,0.27179356591045745,0.51638636702171,0.3949453920319386,1.2863020037686608,-0.06480379588709152,1.2863020037686608,-0.36882191692968064,1.5414559276361184,0.3540841185619894,0.4356160170646649 3367 Side of membrane 17 73 2.5155886519896606 0.0118833787076881 P10321,P02786,P10619,P04439,P55899,P62942,P17900,Q08431,P42892,P01889,Q6YHU6,Q9BYB4,P11279,P61353,Q14118,P46940,P35579 Localization GO Cellular component msigdb_gocc 213,67,68,73,43,75,46,233,16,84,279,191,90,275,327,246,245 1898,2844,1299,1558,501,2503,2154,84,67,2155,73,900,1309,1037,3340,2340,213,68,2587,90,1572,542,2798,1991,1992,46,2433,2435,2436,968,2800,846,2078,245,3066,2355,16,342,246,597,2086,43,275,855,1681,1055,75,1245,1483,2813,2744,233,798,327,1778,3102,2875,279,1948,1954,3289,2761,2626,191,1357,1079,571,2128,2054,2056,951,3088,3172 -0.1940306860173823,-0.7267490661171271,0.10496721166567786,-0.022088097488964575,0.6757140740040977,-0.5017540153159744,-0.3248598804887178,1.9985415804284918,2.202814512277326,-0.3248598804887178,2.1011771507196184,0.3540841185619894,0.10496721166567786,0.27179356591045745,-2.3646418191340213,-0.412958796825298,1.212138715175788,2.1690444425785262,-0.546410842239735,1.8948765913387664,-0.022088097488964575,0.6361522503407359,-0.6814093200124656,-0.23746346936348223,-0.23746346936348223,3.014617485988229,-0.4572697498231123,-0.4572697498231123,-0.4572697498231123,0.31303318522898527,-0.6814093200124656,0.3949453920319386,-0.2810734678085235,1.1373892537486945,-0.9559681035265681,-0.412958796825298,4.4588127644301565,0.909473770504105,1.1373892537486945,0.5964120554641071,-0.2810734678085235,3.0458947300580568,1.0620389315076852,0.3949453920319386,-0.06480379588709152,0.27179356591045745,2.0670777141599412,0.14695211780225223,0.020446217421404334,-0.6814093200124656,-0.6362392226649662,1.1748381597601374,0.4356160170646649,0.9478531474732188,-0.10770002139860704,-1.0023112020703986,-0.7267490661171271,1.0620389315076852,-0.1940306860173823,-0.1940306860173823,-1.52282763066264,-0.6362392226649662,-0.546410842239735,1.3231682601538646,0.10496721166567786,0.27179356591045745,0.6361522503407359,-0.2810734678085235,-0.23746346936348223,-0.23746346936348223,0.3540841185619894,-0.9559681035265681,-1.0954913801193207 3367 Polysome 18 47 2.5104558056170263 0.0120575413787689 Q02543,Q9Y3U8,Q07020,P62753,P62899,Q02878,Q92616,P62701,P84098,P63173,P83881,P62266,P62888,P35580,P62917,P62424,P62910,P83731 Localization GO Cellular component msigdb_gocc 220,102,134,119,198,366,238,471,323,140,232,230,231,387,188,276,247,155 1660,2431,3224,1312,3092,1833,2254,2800,387,1481,1926,1242,2917,230,855,276,471,119,1681,231,198,1244,247,2264,188,140,155,232,323,1686,220,366,515,2182,134,1488,1339,2284,611,2883,3107,2826,238,3318,1213,2057,102 -0.06480379588709152,-0.4572697498231123,-1.2838097038521317,0.10496721166567786,-1.0023112020703986,-0.15077592925131486,-0.36882191692968064,-0.6814093200124656,0.8322262551325478,0.020446217421404334,-0.1940306860173823,0.14695211780225223,-0.7722577547913748,1.1748381597601374,0.3949453920319386,1.0620389315076852,0.7150999985878068,1.613148049789865,-0.06480379588709152,1.1748381597601374,1.2863020037686608,0.14695211780225223,1.1373892537486945,-0.36882191692968064,1.3231682601538646,1.5054130123499248,1.4329258820598159,1.1748381597601374,0.9478531474732188,-0.06480379588709152,1.212138715175788,0.8709321917690549,0.6757140740040977,-0.3248598804887178,1.5414559276361184,0.020446217421404334,0.10496721166567786,-0.36882191692968064,0.5964120554641071,-0.7267490661171271,-1.0023112020703986,-0.6814093200124656,1.1748381597601374,-1.7657985305992057,0.18875209347989597,-0.23746346936348223,1.7549981936289338 3367