term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Predicted membrane proteins 173 473 8.287166295361763 1.1597842935256632e-16 Q9UIQ6,Q8IXU6,Q99720,Q14108,P11117,Q5BJF2,O43772,P08183,Q8WTV0,Q8NCC3,O75844,Q9BQE5,O60637,P42892,Q15125,Q16850,Q5KU26,Q9NS69,O60830,O43657,O75976,Q14739,P13473,Q9UBM7,P02786,P11717,O43676,P11279,P51790,P35610,Q9NR77,P67812,Q8NBX0,Q8IV08,O94813,Q15392,Q9Y6M7,O95342,P24390,O75964,O15118,Q9H061,Q99595,Q9H490,Q5VW38,Q567V2,Q9UDX5,Q99808,Q7Z2K6,O14786,O60725,O15127,P51798,Q13423,Q96GC9,P51572,Q9Y619,Q9HD45,P01889,Q7Z7H5,P43307,Q8N511,P04439,Q969E2,P55011,Q9BTX1,Q9NZQ3,O43324,Q9BUN8,Q6ZRP7,P35613,P08195,Q92542,Q15629,P20645,O43169,P30519,Q9UM00,Q9Y266,Q9ULH0,P09601,P56589,Q14728,Q9UII4,Q9NX47,Q6UWP7,P78310,O15260,Q6ZXV5,Q99805,Q8WY22,Q9NQC3,P98194,P53634,Q9Y3E0,Q96A26,Q86UE4,O75915,O75845,P50402,Q9BXK5,Q96N66,Q99735,Q5J8M3,Q06136,Q9Y282,Q9HD20,Q9H1A4,Q9BTV4,O14828,Q969V3,Q969M3,O14975,O75165,P49257,P49755,P51648,P53985,Q15758,Q8N0U8,Q9BT22,Q14165,Q13190,P24539,Q16799,Q3SXM5,Q6NW34,Q96KA5,Q9P2W9,Q15363,O95674,Q12907,O96005,O15258,P37268,P35080,Q8IUX1,Q9Y320,Q15041,Q8TBA6,O96011,O43491,P50851,Q9BVK6,Q92896,Q96A57,Q93050,Q9Y450,Q8TEM1,Q9Y487,Q8WVX9,Q8N1F7,O15400,P12235,Q14674,Q4G176,Q07065,Q86XL3,Q96HC4,Q969N2,Q5T4S7,O75027,P11166,P13073,Q6UW02,Q5VV42,Q9BU23,Q9H3N1,Q9NX40,Q53GQ0,Q9Y639,Q15070,Q14126 Functions Protein Atlas Protein class protein_atlas_protein_class 2,6,7,8,9,11,12,13,14,15,19,23,21,25,26,27,28,29,32,33,34,35,36,38,41,44,46,48,49,53,57,59,60,63,68,71,72,69,74,77,75,81,90,91,88,87,100,99,98,97,102,113,115,117,118,122,127,126,120,124,121,131,128,135,138,140,142,136,149,148,145,144,158,156,152,150,153,172,184,183,173,174,177,199,198,192,188,185,205,207,206,208,204,203,226,224,222,213,212,217,244,242,243,239,234,264,262,260,258,249,285,284,266,269,272,274,275,276,310,313,316,309,306,299,340,342,343,347,351,339,323,336,324,322,332,331,371,379,369,373,355,353,362,418,412,414,413,429,409,430,410,408,383,391,403,404,401,452,456,453,448,434,437,438,493,491,501,503,506,489,512,488,487 565,465,1559,1205,2578,1325,1778,1433,1780,1882,2447,97,249,1209,943,1329,860,266,75,113,861,322,185,1022,2198,1440,1332,383,150,789,136,353,33,46,1116,12,862,706,946,1216,2379,21,102,32,2582,434,269,1446,1024,2381,1219,2201,518,1447,2011,19,212,213,2931,77,34,2832,68,2453,2382,1574,2524,572,1668,1788,1342,1452,1669,69,1343,574,2203,323,1027,575,795,324,355,796,2457,2458,120,41,128,519,641,1895,1223,797,578,13,144,1581,173,1030,2119,2923,9,437,1033,48,44,391,1458,438,36,1131,1352,957,2632,1686,152,523,2024,1232,74,299,805,653,2833,153,807,1040,1587,2861,331,1801,53,145,1361,332,2869,1363,2771,723,875,25,121,969,591,1475,2034,272,274,2223,217,877,362,2224,1810,122,275,49,115,1052,2640,203,276,1369,138,2038,1817,174,2227,882,2720,2745,2320,1483,883,482,2877,59,188,204,1604,735,1376,1261,484,234,2046,401,1933,1378,1934,1264,336,1608,306,1064,1155,2482,117,1157,1719,1498,826,8,487,309,2238,2146,403,177,35,982,1382,2597,369,488,1613,26,339,541,71,156,901,2054,310,1505,985,1271,1728,340,27,2599,1383,342,2600,404,2334,2150,489,87,11,1272,239,986,747,28,606,2725,448,491,88,2727,1511,1274,343,2339,2057,608,1621,904,2411,493,1388,192,1171,148,205,752,98,2854,1172,124,222,547,452,2778,1078,371,63,1955,1739,2604,2416,6,2921,1080,2417,313,408,1081,911,2498,131,679,913,914,1516,2159,2160,60,15,2161,2903,758,549,2256,1519,2907,614,373,1741,1631,1850,680,409,14,836,410,1178,206,158,2934,1083,837,2346,916,761,2263,552,412,413,135,284,453,285,2816,224,1294,414,2423,554,1963,2349,2731,118,456,1400,347,996,242,2561,2562,1969,2067,685,1529,1752,1530,920,686,1753,766,90,7,243,207,99,2734,2759,23,1186,1533,688,316,258,1859,140,501,149,1535,1406,418,244,1000,2505,2506,81,260,1537,1192,1864,2429,845,503,1538,91,2357,2178,1300,923,693,2572,262,126,1410,1411,208,57,29,927,1644,1415,2184,1766,506,198,2088,930,696,2188,142,630,2918,2616,698,351,1199,38,1421,1200,1422,100,1423,1871,2859,2364,199,2,183,2091,172,935,1647,2093,703,184,2094,264,2095,1110,2442,1429,1996,1874,379,2293,226,1431,2444,429,430,1999,1016,1320,1322,2711,127,512,2786,2371,1557,1558,72 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2937 Endoplasmic reticulum 107 412 5.696397128512775 1.2236566679545266e-08 O75503,Q99720,Q14108,Q5BJF2,O75844,Q9BQE5,Q15125,Q16850,Q14739,Q9UBM7,P07099,Q02818,O43852,P80303,Q9BTY2,P35610,Q13510,Q9UQB8,P10619,P67812,P61916,Q8IV08,Q9UMX5,Q15392,P24390,O15118,Q14257,Q32P28,P30536,Q9H490,P04062,P15289,Q7Z2K6,O60725,Q96AY3,Q96GC9,P51572,P01889,Q7Z7H5,Q01105,P43307,Q8N511,P04439,P62847,Q9BUN8,P35613,Q92542,Q15629,P30519,Q9UM00,P09601,P56589,Q9NX47,Q9H8Y8,Q86SZ2,Q6UWP7,O15260,Q6ZXV5,Q9NQC3,P98194,O15460,P53634,Q9Y3E0,Q8NFQ8,Q86UE4,O75915,O75845,P50402,Q96N66,Q99735,Q5J8M3,Q15293,O15498,O60762,Q06136,Q10471,Q9Y282,Q9HD20,Q9BTV4,P61353,O94979,Q969V3,Q969M3,O14975,P49257,P49755,P51648,Q8N0U8,Q9BT22,Q14165,Q13190,Q96HY6,Q16799,Q9P2W9,Q15363,O95674,Q12907,O15258,P37268,Q9Y320,Q15041,P50851,Q9BVK6,Q96A57,Q92890,Q9Y296,Q8TEM1 Localization GO Cellular component msigdb_gocc 4,7,8,11,19,23,26,27,35,38,39,40,47,50,52,53,55,56,58,59,62,63,65,71,74,75,79,80,82,91,86,95,98,102,105,118,122,120,124,123,121,131,128,139,149,145,158,156,153,172,173,174,198,197,194,192,185,205,208,204,200,203,226,223,222,213,212,217,242,243,239,237,227,228,234,235,264,262,258,252,250,285,284,266,272,274,275,313,316,309,306,346,340,351,339,323,336,322,332,379,369,362,418,414,411,425,409 565,465,1559,1325,1326,1778,2102,2447,1209,860,266,2579,75,861,322,185,1022,2198,1657,200,227,2581,789,944,1212,2377,1660,1443,47,2379,569,1118,102,228,1335,517,1024,1219,4,1447,2299,19,212,213,2832,950,865,436,1786,1573,2524,250,572,1342,1669,1026,640,1343,951,2203,323,1344,795,576,796,2456,2457,1790,120,86,128,2206,519,641,1895,2584,952,39,1674,1455,2526,173,1678,2923,58,2716,868,520,956,1899,1229,1585,95,1352,957,1901,2632,1231,2121,1135,2023,2634,1232,2531,585,74,650,964,1689,1354,871,1907,2682,804,805,872,1356,2217,1465,1909,153,655,82,806,1138,2861,1801,1141,53,145,1142,809,332,2869,1363,722,588,875,121,589,440,590,591,1591,2391,2034,480,1694,272,274,217,970,362,1810,122,275,1052,2132,1145,2539,2134,1924,203,1147,2478,2540,2642,1925,174,2227,2720,2543,1599,729,594,1373,972,1600,252,1256,1483,883,62,1601,816,817,1705,1058,1059,139,2809,2877,1820,2400,59,50,819,974,1603,204,735,123,2594,1931,40,483,484,234,537,401,235,1264,1935,336,2872,1608,1063,306,2690,55,1719,1498,826,8,309,79,2238,2146,1265,35,1382,1830,2597,2852,369,2775,2242,1613,26,237,1725,339,1164,71,2485,745,156,901,1616,2054,340,27,2599,80,489,2601,11,239,986,491,405,1511,449,1274,2339,904,751,192,1276,205,98,755,124,194,222,547,452,1078,1279,63,1955,2496,1739,2921,313,911,2498,131,679,913,914,1516,2062,2159,1518,2256,223,2907,2163,614,2257,1850,2164,680,759,1521,409,1522,1288,1178,2066,158,1083,837,761,411,2265,284,453,285,1294,414,2423,105,1963,118,838,346,996,242,2067,685,2068,2609,7,243,2733,2734,23,2900,2072,1533,316,258,52,501,149,1535,1406,418,1000,557,2428,503,1639,91,1099,1300,197,2572,262,1411,208,1866,927,928,851,198,2879,2088,628,696,2187,630,2616,698,1420,351,1311,38,1991,2618,1423,1313,1107,2763,1770,172,65,1873,935,1012,56,264,425,2194,379,2098,2293,226,2710,938,511,2802,1320,2786,432,2371,856,2623,1558,636 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2937 Vacuolar lumen 22 54 5.15167316753175 2.581726803810852e-07 P07602,Q14108,P11117,P06865,P38571,P15586,P50897,O14773,P04066,P06280,P13473,P16278,P54802,Q9BTY2,Q92820,Q13510,P10619,P07686,P61916,Q8IV08,P04062,P15289 Localization GO Cellular component msigdb_gocc 3,8,9,16,17,20,22,24,30,31,36,37,42,52,54,55,58,61,62,63,86,95 24,1443,2457,86,30,31,16,2304,1580,3,61,713,129,58,9,1457,2528,36,95,20,37,872,1466,2869,17,660,812,22,1479,1701,203,42,2478,1703,62,1151,1489,2690,55,8,669,63,1518,54,1963,686,2351,52,999,1098,181,2829,2188,1013 3.7652112572324823,-0.04871252906513763,-0.6486147893595557,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,-0.5236513396667263,-0.10591263929674817,5.131894866624145,2.1898966319486153,0.38683824468201267,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,-0.7120374352425395,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,0.2816075367943659,-0.04871252906513763,-1.6665070292939557,3.9856208887046614,0.4385452506124256,0.33452611576463864,3.8063874677803375,-0.04871252906513763,-0.16372948749216756,1.057240248022844,3.078582353860239,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.11919997011538998,-0.04871252906513763,-0.906083163548422,2.5014551385438826,4.712282471751374,0.4385452506124256,2.157214859958303,-0.04871252906513763,2.5311775269119203,-0.2812183777015856,0.4385452506124256,-0.5236513396667263,2.618889115071512,0.228081190180689,0.17394576765407171,1.1442885584140452,-1.311278575581721,-0.4011890781327106,0.228081190180689 2937 Lysosome 25 44 5.137017057845969 2.7913362806059093e-07 P07602,O75503,P10253,Q14108,P11117,Q8NCC3,P06865,P38571,P15586,P50897,O14773,P04066,P06280,P13473,P16278,P54802,P11717,P11279,Q13510,P10619,P07686,P61916,O15118,P04062,P15289 Processes and pathways KEGG Pathways msigdb_kegg 3,4,129,8,9,15,16,17,20,22,24,30,31,36,37,42,44,48,55,58,61,62,75,86,95 1020,1115,24,75,1443,2105,4,86,30,31,16,3,61,326,798,129,58,9,48,44,36,95,20,37,152,17,22,203,42,1149,62,1062,823,55,8,15,682,413,1408,2188,2782,1768,1014,430 0.17394576765407171,0.11919997011538998,3.7652112572324823,1.9547430671585866,-0.04871252906513763,-0.4011890781327106,4.878143286316388,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,0.7836800160884329,0.33452611576463864,1.3941514953495935,2.3177619175977977,4.437559793002022,2.618889115071512,2.94951498403428,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,1.229406481355582,3.9856208887046614,3.8063874677803375,1.057240248022844,3.078582353860239,0.11919997011538998,2.157214859958303,0.17394576765407171,0.33452611576463864,2.5014551385438826,4.712282471751374,4.0999276525600274,0.4385452506124256,0.688050566378247,0.007872098580347686,-0.4011890781327106,-1.1058199287517425,-0.16372948749216756,0.228081190180689,0.688050566378247 2937 Vacuole 42 173 4.933103600727267 8.09331990571786e-07 Q8N511,Q9UIQ6,P07602,O75503,P42785,P10253,Q14108,P11117,Q5BJF2,Q8WTV0,Q8NCC3,P06865,P38571,P15586,P08195,P50897,O14773,P42892,Q92542,P20645,P04066,P06280,P13473,P16278,P54802,Q9UHG3,P11279,P51790,Q9BTY2,Q92820,Q13510,P10619,P07686,P61916,Q8IV08,O15118,P04062,P15289,Q9H0B6,Q15165,P51798,Q96GC9 Localization GO Cellular component msigdb_gocc 131,2,3,4,5,129,8,9,11,14,15,16,17,20,144,22,24,25,158,152,30,31,36,37,42,45,48,49,52,54,55,58,61,62,63,75,86,95,107,110,115,118 2578,1020,1115,24,75,185,383,704,1443,2105,946,570,1120,269,2831,4,1571,2114,1670,2457,86,30,641,31,16,2304,1128,1580,3,61,713,1896,144,867,2526,326,1676,129,58,9,1457,2528,48,36,95,20,37,1901,152,961,869,1232,2682,804,872,1466,656,1240,967,2869,17,2127,1363,588,5,875,25,2129,1247,660,812,362,22,1479,1480,1143,1051,49,115,1052,1701,203,2899,42,2478,1925,2543,1599,972,1703,1149,62,2773,2870,818,1927,1151,1062,887,1489,2649,401,738,823,2872,2690,55,1158,2750,8,669,1382,110,1164,11,406,63,131,1518,15,2256,14,615,551,158,54,413,2664,414,1963,1747,2818,118,498,686,2351,2857,286,500,52,999,1408,2760,107,1098,1760,502,181,778,2781,852,506,2829,2188,697,2616,2922,1420,1009,45,2782,2,1316,2368,935,1013,2672,1014,634,430,938,2711,2371 -0.7760889340064466,0.17394576765407171,0.11919997011538998,3.7652112572324823,1.9547430671585866,1.101010637080487,0.688050566378247,0.38683824468201267,-0.04871252906513763,-0.4011890781327106,0.228081190180689,0.48964847025575964,0.11919997011538998,0.8770244243066478,-1.3810415738737563,4.878143286316388,-0.10591263929674817,-0.4011890781327106,-0.16372948749216756,-0.6486147893595557,1.8491689704918812,3.6169723053440874,0.4385452506124256,3.6169723053440874,4.024165938684547,-0.5236513396667263,0.11919997011538998,-0.10591263929674817,5.131894866624145,2.1898966319486153,0.38683824468201267,-0.2812183777015856,1.2712655154383892,0.2816075367943659,-0.7120374352425395,0.7836800160884329,-0.16372948749216756,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,-0.7120374352425395,2.618889115071512,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,-0.2812183777015856,1.229406481355582,0.228081190180689,0.2816075367943659,0.06384250748914849,-0.906083163548422,0.33452611576463864,0.2816075367943659,-0.04871252906513763,0.4385452506124256,0.06384250748914849,0.228081190180689,-1.6665070292939557,3.9856208887046614,-0.4011890781327106,0.007872098580347686,0.48964847025575964,4.863421508907323,0.2816075367943659,3.744431287238993,-0.4011890781327106,0.06384250748914849,0.4385452506124256,0.33452611576463864,0.7361572254974664,3.8063874677803375,-0.04871252906513763,-0.04871252906513763,0.11919997011538998,0.17394576765407171,2.618889115071512,1.473918375909616,0.17394576765407171,-0.16372948749216756,1.057240248022844,-2.0378507439803,3.078582353860239,-0.6486147893595557,-0.2812183777015856,-0.7120374352425395,-0.10591263929674817,0.228081190180689,-0.16372948749216756,0.11919997011538998,2.157214859958303,-1.1058199287517425,-1.6665070292939557,0.33452611576463864,-0.2812183777015856,0.11919997011538998,0.17394576765407171,0.2816075367943659,-0.04871252906513763,-0.8407704557687973,0.688050566378247,0.38683824468201267,0.33452611576463864,-1.6665070292939557,-0.906083163548422,2.5014551385438826,0.11919997011538998,-1.0386067543300004,4.712282471751374,0.4385452506124256,0.007872098580347686,1.5131791067781917,0.11919997011538998,4.2819961355673675,0.688050566378247,2.157214859958303,1.3941514953495935,-0.04871252906513763,4.0999276525600274,-0.4621081592112762,4.192232038011874,0.48964847025575964,0.5401492501085412,1.229406481355582,2.5311775269119203,0.688050566378247,-0.8407704557687973,0.688050566378247,-0.2812183777015856,-0.16372948749216756,-1.2421547136861633,1.473918375909616,0.5900489466309929,0.4385452506124256,-0.5236513396667263,-1.5224894117754426,0.8770244243066478,0.5900489466309929,2.618889115071512,0.228081190180689,0.007872098580347686,-1.0386067543300004,1.59049366572062,0.17394576765407171,-0.16372948749216756,0.5900489466309929,1.1442885584140452,0.38683824468201267,-1.1058199287517425,0.33452611576463864,0.5900489466309929,-1.311278575581721,-0.4011890781327106,0.4385452506124256,-0.7760889340064466,-3.510150275167924,0.007872098580347686,0.228081190180689,2.8697220435010813,-1.1058199287517425,5.198840694526526,0.06384250748914849,-0.5236513396667263,0.2816075367943659,0.228081190180689,-0.8407704557687973,0.228081190180689,0.48964847025575964,0.688050566378247,0.2816075367943659,-0.906083163548422,-0.5236513396667263 2937 Azurophil granule 21 57 4.665505040398823 3.0785994873383515e-06 P07602,P10253,P42785,P06865,Q99829,P15586,Q92542,P04066,P06280,P13473,P16278,Q9H7Z7,P11279,Q9BTY2,Q92820,P10619,P07686,P61916,O15260,P53634,P15289 Localization GO Cellular component msigdb_gocc 3,129,5,16,286,20,158,30,31,36,37,181,48,52,54,58,61,62,185,203,95 2578,185,383,1443,1120,269,2457,30,31,16,2304,1580,3,61,129,58,2528,48,36,95,20,37,872,1466,1363,5,812,1479,1480,1143,1052,1701,203,2478,1703,62,1151,1489,401,2690,669,406,1518,2256,158,54,1963,686,2351,286,52,1098,181,2829,2188,2616,1013 -0.7760889340064466,1.101010637080487,0.688050566378247,-0.04871252906513763,0.11919997011538998,0.8770244243066478,-0.6486147893595557,3.6169723053440874,3.6169723053440874,4.024165938684547,-0.5236513396667263,-0.10591263929674817,5.131894866624145,2.1898966319486153,1.3941514953495935,2.3177619175977977,-0.7120374352425395,2.618889115071512,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,0.2816075367943659,-0.04871252906513763,0.007872098580347686,4.863421508907323,0.33452611576463864,-0.04871252906513763,-0.04871252906513763,0.11919997011538998,0.17394576765407171,-0.16372948749216756,1.057240248022844,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.11919997011538998,-0.04871252906513763,0.688050566378247,-0.906083163548422,0.4385452506124256,0.688050566378247,-0.04871252906513763,-0.4621081592112762,1.229406481355582,2.5311775269119203,-0.2812183777015856,0.4385452506124256,-0.5236513396667263,0.8770244243066478,2.618889115071512,0.17394576765407171,1.1442885584140452,-1.311278575581721,-0.4011890781327106,-0.7760889340064466,0.228081190180689 2937 Abnormality of the spleen 20 109 4.656174073998338 3.22139595088089e-06 P07602,P10253,Q14108,P38571,P15586,P04066,Q14739,P16278,P54802,Q13510,P10619,P07686,P61916,Q15392,O95342,O15118,P04062,P51798,Q9Y285,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,129,8,17,20,30,35,37,42,55,58,61,62,71,69,75,86,115,119,120 1020,1563,1115,1329,75,228,707,1445,518,1890,212,1452,69,1892,2015,1221,1790,120,1894,86,30,1672,2206,1673,578,1127,3,61,1456,129,58,437,1033,2019,799,187,800,20,37,2213,2681,961,802,2807,1586,804,586,653,1136,330,1361,657,2314,17,2471,1803,1473,1590,1248,1367,725,362,1920,2037,115,1147,1053,42,2643,2396,62,1932,443,484,2140,538,1156,2691,55,1718,826,8,147,35,71,1835,449,750,2796,676,2159,1742,1289,2700,411,1294,346,1970,316,2186,2187,2188,1767,2093,119,1996,1319,1878,2711 0.17394576765407171,-0.10591263929674817,0.11919997011538998,0.007872098580347686,1.9547430671585866,0.9681807864168185,0.38683824468201267,-0.04871252906513763,0.5401492501085412,-0.2812183777015856,1.0129671489863166,-0.04871252906513763,2.057376685439682,-0.2812183777015856,-0.34089288926430916,0.06384250748914849,-0.22216432068703482,1.434245143990909,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.16372948749216756,-0.4621081592112762,-0.16372948749216756,0.48964847025575964,0.11919997011538998,5.131894866624145,2.1898966319486153,-0.04871252906513763,1.3941514953495935,2.3177619175977977,0.6393489264185823,0.17394576765407171,-0.34089288926430916,0.33452611576463864,1.101010637080487,0.33452611576463864,3.887244197186541,3.4162772870291325,-0.4621081592112762,-0.906083163548422,0.228081190180689,0.33452611576463864,-1.2421547136861633,-0.10591263929674817,0.33452611576463864,0.48964847025575964,0.4385452506124256,0.11919997011538998,0.7836800160884329,0.007872098580347686,0.4385452506124256,-0.5236513396667263,3.9856208887046614,-0.6486147893595557,-0.22216432068703482,-0.04871252906513763,-0.10591263929674817,0.06384250748914849,0.007872098580347686,0.38683824468201267,0.7361572254974664,-0.2812183777015856,-0.34089288926430916,1.473918375909616,0.11919997011538998,0.17394576765407171,3.078582353860239,-0.8407704557687973,-0.5858198190406446,2.157214859958303,-0.2812183777015856,0.6393489264185823,0.5900489466309929,-0.4011890781327106,0.5401492501085412,0.11919997011538998,-0.906083163548422,2.5014551385438826,-0.16372948749216756,0.33452611576463864,4.712282471751374,1.2712655154383892,3.4391717680711436,2.057376685439682,-0.22216432068703482,0.6393489264185823,0.38683824468201267,-1.1736688722168886,0.4385452506124256,-0.4011890781327106,-0.16372948749216756,0.06384250748914849,-0.906083163548422,0.688050566378247,0.06384250748914849,0.7836800160884329,-0.2812183777015856,0.8306316454399105,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,-0.16372948749216756,-0.34089288926430916,1.473918375909616,-0.2812183777015856,0.06384250748914849,-0.22216432068703482,-0.906083163548422 2937 Vacuolar membrane 22 103 4.505604723597628 6.618418824322347e-06 Q8N511,Q9UIQ6,P07602,O75503,P42785,P10253,Q14108,P11117,Q8WTV0,P08195,Q92542,P42892,P13473,P11279,P51790,P10619,Q8IV08,O15118,P04062,Q9H0B6,P51798,Q96GC9 Localization GO Cellular component msigdb_gocc 131,2,3,4,5,129,8,9,14,144,158,25,36,48,49,58,63,75,86,107,115,118 1020,1115,75,185,383,2105,946,1120,269,4,1571,2114,1670,86,641,2304,3,1896,144,867,2526,326,129,58,9,1457,48,36,152,961,869,1232,656,1240,967,2127,1363,588,5,25,1247,1143,1051,49,115,1052,2899,1925,2543,972,1149,2773,2870,818,1927,1062,2649,401,738,823,2750,8,1382,1164,406,63,131,2256,14,615,551,158,413,1747,2818,118,498,2857,286,500,1408,2760,107,1760,502,778,2781,852,2188,697,2616,2922,1009,2782,2,1316,2368,935,2672,1014,634,430,2711 0.17394576765407171,0.11919997011538998,1.9547430671585866,1.101010637080487,0.688050566378247,-0.4011890781327106,0.228081190180689,0.11919997011538998,0.8770244243066478,4.878143286316388,-0.10591263929674817,-0.4011890781327106,-0.16372948749216756,1.8491689704918812,0.4385452506124256,-0.5236513396667263,5.131894866624145,-0.2812183777015856,1.2712655154383892,0.2816075367943659,-0.7120374352425395,0.7836800160884329,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,2.618889115071512,3.4162772870291325,1.229406481355582,0.228081190180689,0.2816075367943659,0.06384250748914849,0.4385452506124256,0.06384250748914849,0.228081190180689,-0.4011890781327106,0.007872098580347686,0.48964847025575964,4.863421508907323,3.744431287238993,0.06384250748914849,0.11919997011538998,0.17394576765407171,2.618889115071512,1.473918375909616,0.17394576765407171,-2.0378507439803,-0.2812183777015856,-0.7120374352425395,0.228081190180689,0.11919997011538998,-1.1058199287517425,-1.6665070292939557,0.33452611576463864,-0.2812183777015856,0.17394576765407171,-0.8407704557687973,0.688050566378247,0.38683824468201267,0.33452611576463864,-1.0386067543300004,4.712282471751374,0.007872098580347686,0.11919997011538998,0.688050566378247,2.157214859958303,1.3941514953495935,-0.4621081592112762,4.192232038011874,0.48964847025575964,0.5401492501085412,1.229406481355582,0.688050566378247,-0.16372948749216756,-1.2421547136861633,1.473918375909616,0.5900489466309929,-1.5224894117754426,0.8770244243066478,0.5900489466309929,0.007872098580347686,-1.0386067543300004,1.59049366572062,-0.16372948749216756,0.5900489466309929,0.38683824468201267,-1.1058199287517425,0.33452611576463864,-0.4011890781327106,0.4385452506124256,-0.7760889340064466,-3.510150275167924,0.228081190180689,-1.1058199287517425,5.198840694526526,0.06384250748914849,-0.5236513396667263,0.2816075367943659,-0.8407704557687973,0.228081190180689,0.48964847025575964,0.688050566378247,-0.906083163548422 2937 Lysosomal lumen 20 29 4.458399003758515 8.257408741441097e-06 P07602,Q14108,P11117,P06865,P38571,P15586,P50897,O14773,P04066,P06280,P13473,P16278,P54802,Q13510,P10619,P07686,P61916,Q8IV08,P04062,P15289 Localization GO Cellular component msigdb_gocc 3,8,9,16,17,20,22,24,30,31,36,37,42,55,58,61,62,63,86,95 24,1443,86,30,31,16,3,61,713,129,58,9,1457,36,95,20,37,2869,17,660,22,42,62,55,8,63,1518,999,2188 3.7652112572324823,-0.04871252906513763,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,0.38683824468201267,1.3941514953495935,2.3177619175977977,4.437559793002022,-0.04871252906513763,3.4162772870291325,1.7404982072045598,3.887244197186541,3.4162772870291325,-1.6665070292939557,3.9856208887046614,0.4385452506124256,3.8063874677803375,3.078582353860239,2.157214859958303,2.5014551385438826,4.712282471751374,2.157214859958303,-0.04871252906513763,0.228081190180689,-0.4011890781327106 2937 Splenomegaly 17 80 4.329643701758141 1.493507860828025e-05 P07602,Q14739,P16278,Q15392,P10253,Q14108,O95342,P54802,O15118,P38571,P51798,P15586,Q13510,P61916,P04062,P01889,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,35,37,71,129,8,69,42,75,17,115,20,55,62,86,120,30 1020,1563,1115,1329,75,228,707,1445,518,1890,69,1892,1221,1790,120,1894,86,30,1672,2206,1673,578,1127,3,129,437,1033,2019,799,187,800,20,37,2213,2681,961,802,2807,804,586,653,1136,330,1361,657,17,1590,1367,725,362,2037,115,1147,1053,42,2396,62,1932,484,538,55,1718,8,147,35,71,1835,449,750,2796,2159,2700,411,1294,346,316,2186,2187,2188,2093 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2937 Potential drug targets 80 460 4.324838397119447 1.5264372009271554e-05 P07602,Q14108,P11117,O15164,O43772,P06865,P38571,O75844,P15586,P50897,O14773,P42892,Q15125,P04066,P06280,Q14739,P13473,P16278,Q9UBM7,P07099,P54802,Q13510,P10619,P07686,P61916,Q8IV08,Q15392,O95342,O15118,Q32P28,Q9H061,Q4J6C6,P04062,P15289,Q01433,Q96AY3,P51798,P51572,Q9Y619,Q8N511,P04439,Q14376,O60826,Q9H4A3,Q9UM00,Q16851,Q14004,P40855,Q9ULH0,P09601,P56589,Q96L58,P12955,Q6ZXV5,O15460,P53634,Q6NUK1,O75845,Q96N66,Q9Y4U1,P41227,O60762,Q06136,Q10471,O94979,P49257,P51648,P53985,Q9BT22,Q9H2D1,O60493,P05165,P50570,P19404,P33991,P37268,Q8IUX1,Q96BN8,Q9Y320,Q9Y5K6 Functions Protein Atlas Protein class protein_atlas_protein_class 3,8,9,10,12,16,17,19,20,22,24,25,26,30,31,35,36,37,38,39,42,55,58,61,62,63,71,69,75,80,81,85,86,95,103,105,115,122,127,131,128,147,143,160,172,168,166,164,183,173,174,196,187,205,200,203,220,212,242,248,231,228,234,235,250,272,275,276,316,317,293,298,303,328,330,332,371,374,379,382 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2937 Receptor 16 33 4.256082378992519 2.080400797099813e-05 Q14739,P78310,O14786,Q99720,Q14108,P02786,P24390,P11717,Q8WTV0,O15118,P11279,P35613,Q9NS69,Q9Y2W1,Q5KU26,P20645 Functions Protein Atlas Molecular function protein_atlas_molecular_function 35,188,97,7,8,41,74,44,14,75,48,145,29,265,28,152 1325,97,75,861,41,1345,797,952,1455,1456,1678,48,44,1682,152,74,807,145,188,484,2482,8,35,310,28,14,1293,2070,7,29,1428,265,1320 0.007872098580347686,1.7035577277228184,1.9547430671585866,0.2816075367943659,3.1288971739076072,0.007872098580347686,0.33452611576463864,0.228081190180689,-0.04871252906513763,-0.04871252906513763,-0.16372948749216756,2.618889115071512,2.94951498403428,-0.16372948749216756,1.229406481355582,1.9892736116862897,0.33452611576463864,1.2712655154383892,1.101010637080487,0.5900489466309929,-0.6486147893595557,4.712282471751374,3.4391717680711436,0.8306316454399105,3.681306413452911,4.192232038011874,0.06384250748914849,-0.34089288926430916,4.758390219688548,3.681306413452911,0.007872098580347686,0.9228702829555585,0.06384250748914849 2937 Steroid metabolic process 14 62 4.20565696807719 2.6032483316118515e-05 Q14739,Q9UBM7,Q15392,O95342,Q8WTV0,O15118,P38571,P30536,Q9BQE5,P35610,Q13510,Q15125,Q16850,P61916 Processes and pathways GO Biological process msigdb_gobp 35,38,71,69,14,75,17,82,23,53,55,26,27,62 266,75,212,1573,69,1343,2457,86,1895,357,799,521,1230,1352,2023,2634,2462,2466,653,82,53,332,2869,17,2472,2391,2744,1249,2037,1701,62,1375,1709,1932,821,1936,55,827,2146,35,1382,26,1833,71,1615,1067,2054,27,489,406,14,1394,416,2501,23,2275,1002,38,377,1425,2763,1873 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2937 Circulatory system process 17 60 4.057313000582896 4.964053491751663e-05 Q9HB40,Q9UIQ6,P10253,P53985,P42785,P78310,O94813,Q99808,Q07157,P55011,P02786,Q96AC1,P08183,O75844,Q9H4A3,P09601,P42892 Processes and pathways GO Biological process msigdb_gobp 0,2,129,276,5,188,68,99,255,138,41,241,13,19,160,173,25 1326,1563,1437,1118,1784,19,2452,1450,68,2457,41,1346,2207,1895,13,173,129,437,2210,2884,2911,957,1132,1686,1905,806,807,1473,588,5,25,1248,1915,1249,1145,276,138,1599,1256,1704,188,2593,2401,366,255,2793,1715,1498,487,895,1163,310,2339,1621,241,99,160,0,2187,2 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2937 Lipid localization 14 66 4.008414525636146 6.112775514810487e-05 P07602,Q99720,Q14108,O95342,O43772,P08183,Q8WTV0,O15118,P30536,Q9BQE5,P35610,P04062,P07686,P61916 Processes and pathways GO Biological process msigdb_gobp 3,7,8,69,12,13,14,75,82,23,53,86,61,62 565,292,266,75,185,12,862,1218,69,2203,323,796,2302,86,2680,2304,3,61,1675,13,437,800,2023,2634,718,653,82,2469,2861,53,480,877,62,886,1375,2140,1936,8,2146,1382,2334,406,2339,2063,14,118,416,7,23,1533,1535,2074,1000,2569,318,1300,852,2188,2616,377,933,2090,1109,2368,2371,2623 0.48964847025575964,0.8306316454399105,0.8770244243066478,1.9547430671585866,1.101010637080487,4.2103839880354075,0.2816075367943659,0.06384250748914849,2.057376685439682,-0.4621081592112762,0.7836800160884329,0.33452611576463864,-0.5236513396667263,1.8491689704918812,-0.906083163548422,-0.5236513396667263,5.131894866624145,2.1898966319486153,-0.16372948749216756,4.192232038011874,0.6393489264185823,0.33452611576463864,-0.34089288926430916,-0.8407704557687973,0.38683824468201267,0.4385452506124256,1.8846964555914798,-0.6486147893595557,-1.5941764518204824,2.589890921013961,0.5900489466309929,0.2816075367943659,2.157214859958303,0.2816075367943659,0.007872098580347686,-0.4011890781327106,-0.2812183777015856,4.712282471751374,-0.4011890781327106,0.007872098580347686,-0.5236513396667263,0.688050566378247,-0.5236513396667263,-0.34089288926430916,4.192232038011874,1.473918375909616,0.688050566378247,4.758390219688548,3.8063874677803375,-0.04871252906513763,-0.04871252906513763,-0.34089288926430916,0.228081190180689,-0.7120374352425395,0.8306316454399105,0.06384250748914849,0.33452611576463864,-0.4011890781327106,-0.7760889340064466,0.7361572254974664,0.2816075367943659,-0.34089288926430916,0.17394576765407171,-0.5236513396667263,-0.5236513396667263,-0.7760889340064466 2937 Intrinsic component of plasma membrane 32 60 4.007979862460079 6.124034066634643e-05 Q9UIQ6,P04439,P55011,Q8WTV0,P35613,O60637,Q92542,P20645,O43657,P12235,P53985,Q15758,P02786,P11717,P11279,P51790,Q7L5Y9,O43813,P78310,P11166,Q99805,O15118,Q9BTU6,Q12907,O96005,Q99808,O14786,Q9Y639,O15498,P51572,Q04721,P01889 Localization GO Cellular component msigdb_gocc 2,128,138,14,145,21,158,152,33,391,276,310,41,44,48,49,450,66,188,437,207,75,500,336,324,99,97,512,227,122,484,120 565,1325,97,2003,75,227,33,66,21,795,324,120,41,128,1895,1223,797,2923,437,48,44,391,957,1686,152,805,807,2470,145,1361,122,49,276,1369,138,188,1604,1261,484,1378,336,2482,1725,310,450,547,911,14,158,2733,207,99,500,2508,2185,2,1767,935,2919,512 0.48964847025575964,0.007872098580347686,1.7035577277228184,-0.34089288926430916,1.9547430671585866,0.9681807864168185,3.4619133058097864,2.090959820673029,3.8063874677803375,0.33452611576463864,0.7836800160884329,1.434245143990909,3.1288971739076072,1.3941514953495935,-0.2812183777015856,0.06384250748914849,0.33452611576463864,-3.598238387349531,0.6393489264185823,2.618889115071512,2.94951498403428,0.688050566378247,0.228081190180689,-0.16372948749216756,1.229406481355582,0.33452611576463864,0.33452611576463864,-0.6486147893595557,1.2712655154383892,0.007872098580347686,1.434245143990909,2.618889115071512,0.8770244243066478,0.007872098580347686,1.3126701679029467,1.101010637080487,-0.10591263929674817,0.06384250748914849,0.5900489466309929,0.007872098580347686,0.7836800160884329,-0.6486147893595557,-0.16372948749216756,0.8306316454399105,0.6393489264185823,0.5401492501085412,0.2816075367943659,4.192232038011874,1.229406481355582,-0.9720282133639213,1.057240248022844,1.7035577277228184,0.5900489466309929,-0.6486147893595557,-0.4011890781327106,5.198840694526526,-0.16372948749216756,0.2816075367943659,-2.9956170913795845,0.5900489466309929 2937 Membrane lipid metabolic process 15 33 3.955721911511653 7.630388058577076e-05 P07602,P16278,Q99735,Q99805,Q8NCC3,P06865,O60762,P50897,Q13510,Q9H490,P04062,Q8NBX0,P07686,P04066,P06280 Processes and pathways GO Biological process msigdb_gobp 3,37,243,207,15,16,228,22,55,91,86,60,61,30,31 1022,2198,789,228,1343,86,30,31,16,3,61,37,2023,1237,22,234,1936,55,2487,679,60,15,761,453,2067,243,207,91,2088,696,2188,630,2616 0.17394576765407171,-0.4621081592112762,0.33452611576463864,0.9681807864168185,0.007872098580347686,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,3.4162772870291325,-0.34089288926430916,0.06384250748914849,3.8063874677803375,0.9681807864168185,-0.2812183777015856,2.5014551385438826,-0.6486147893595557,0.4385452506124256,2.222287625540094,4.0999276525600274,0.38683824468201267,0.6393489264185823,-0.34089288926430916,0.9681807864168185,1.057240248022844,1.8491689704918812,-0.34089288926430916,0.4385452506124256,-0.4011890781327106,0.48964847025575964,-0.7760889340064466 2937 Sterol metabolic process 11 35 3.8920709346502234 9.93921736582859e-05 Q14739,Q9UBM7,Q15392,Q8WTV0,O15118,P38571,Q9BQE5,P35610,Q15125,Q16850,P61916 Processes and pathways GO Biological process msigdb_gobp 35,38,71,14,75,17,23,53,26,27,62 75,212,1573,2457,86,799,521,1352,2462,53,332,17,2472,2391,2744,1701,62,1375,1709,1932,1936,827,2146,35,1382,26,1833,71,2054,27,14,23,38,377,2763 1.9547430671585866,1.0129671489863166,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.33452611576463864,0.5401492501085412,0.007872098580347686,-0.6486147893595557,2.589890921013961,0.7836800160884329,3.9856208887046614,-0.6486147893595557,-0.5858198190406446,-1.0386067543300004,-0.16372948749216756,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,4.192232038011874,3.8063874677803375,3.4162772870291325,0.7361572254974664,-1.0386067543300004 2937 Abnormality of femur morphology 12 63 3.8628522254846422 0.0001120708071762 P07602,Q14739,P16278,P55011,Q96AY3,Q32P28,O75844,P51798,Q9Y619,P04062,P04066,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,35,37,138,105,80,19,115,127,86,30,31 1324,1563,1778,942,1332,1118,1663,2009,2112,2299,19,1123,575,796,1894,86,30,2206,31,3,37,1352,1905,964,872,2314,2315,1590,2536,1591,115,2640,1813,138,594,35,983,897,2406,80,449,343,2251,344,1735,1742,1746,1294,105,346,196,1091,1403,1538,1986,851,1766,2188,1108,2709,430,1878,127 0.007872098580347686,-0.10591263929674817,-0.22216432068703482,0.228081190180689,0.007872098580347686,0.11919997011538998,-0.16372948749216756,-0.34089288926430916,-0.4011890781327106,-0.5236513396667263,3.926946339483657,0.11919997011538998,0.48964847025575964,0.33452611576463864,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.4621081592112762,3.6169723053440874,5.131894866624145,3.4162772870291325,0.007872098580347686,-0.2812183777015856,0.228081190180689,0.2816075367943659,-0.5236513396667263,-0.5236513396667263,-0.10591263929674817,-0.7120374352425395,-0.10591263929674817,1.473918375909616,-0.8407704557687973,-0.22216432068703482,1.3126701679029467,0.48964847025575964,3.4391717680711436,0.228081190180689,0.2816075367943659,-0.5858198190406446,1.919885894471246,0.6393489264185823,0.7836800160884329,-0.4621081592112762,0.7836800160884329,-0.16372948749216756,-0.16372948749216756,-0.16372948749216756,0.06384250748914849,1.628562285011634,0.7836800160884329,1.101010637080487,0.17394576765407171,0.007872098580347686,-0.04871252906513763,-0.2812183777015856,0.33452611576463864,-0.16372948749216756,-0.4011890781327106,0.17394576765407171,-0.906083163548422,0.688050566378247,-0.22216432068703482,1.434245143990909 2937 Exopeptidase activity 14 32 3.822349880988544 0.0001321859519756 Q9HB40,Q9H3G5,Q9UIQ6,O75976,Q7Z2K6,P42785,P12955,P02786,Q969V3,P53634,O75844,Q92820,O14773,P10619 Functions GO Molecular function msigdb_gomf 0,1,2,34,98,5,187,41,285,203,19,54,24,58 24,19,34,41,1583,58,187,1796,1136,1361,5,2476,203,663,2325,2237,98,2415,1514,54,285,2817,496,286,1,1983,0,2762,1642,627,2187,2 3.7652112572324823,3.926946339483657,3.4391717680711436,3.1288971739076072,-0.10591263929674817,2.3177619175977977,1.101010637080487,-0.22216432068703482,0.11919997011538998,0.007872098580347686,4.863421508907323,-0.6486147893595557,1.057240248022844,0.4385452506124256,-0.5236513396667263,-0.4621081592112762,1.7035577277228184,-0.5858198190406446,-0.04871252906513763,2.5311775269119203,0.8770244243066478,-1.2421547136861633,0.5900489466309929,0.8770244243066478,5.830215713580066,-0.2812183777015856,5.893957451831641,-1.0386067543300004,-0.10591263929674817,0.48964847025575964,-0.4011890781327106,5.198840694526526 2937 Intrinsic component of organelle membrane 51 109 3.81099170279598 0.000138410413367 Q9BTV4,Q15286,Q15388,P04439,Q86UP2,Q8NE86,Q6UXV4,Q9NZ01,Q9BUN8,Q6ZRP7,Q9HC21,O75844,Q8WVX9,P42892,Q15125,Q15629,O14975,O60830,Q9UM00,Q14739,P13473,P12235,Q9UBM7,Q86XL3,P56589,O96008,Q8TB61,Q5SNT2,Q6P4A7,Q969N2,Q16799,Q9P035,O43505,O15118,Q9NQC3,P98194,Q99595,Q9H490,O15258,Q10471,O95563,O95070,O96011,A0FGR8,Q15070,Q5J8M3,Q15041,P51572,Q9Y282,P01889,Q8TCT9 Localization GO Cellular component msigdb_gocc 258,256,541,128,547,549,281,696,149,148,693,19,410,25,26,156,266,32,172,35,36,391,38,452,174,297,614,606,608,453,340,630,76,75,208,204,90,91,322,235,574,572,355,565,488,239,369,122,264,120,680 565,2518,943,266,75,322,789,1212,76,862,706,32,2009,19,2832,2382,572,1668,1343,574,297,355,120,128,2923,391,36,1686,716,804,805,1909,2315,25,877,1051,122,174,2227,1483,204,1604,235,1608,1157,2238,35,2852,369,488,26,256,541,156,1505,340,830,2487,239,606,987,608,281,148,547,452,1078,2604,2416,2498,914,549,614,680,410,761,453,1294,2561,2067,90,2564,1533,258,149,1535,1407,845,91,923,1302,693,2572,208,2184,1106,696,630,698,38,1871,2859,172,264,1996,2802,1016,1113,2371 0.48964847025575964,-0.7120374352425395,0.228081190180689,0.8770244243066478,1.9547430671585866,0.7836800160884329,0.33452611576463864,0.06384250748914849,1.9547430671585866,0.2816075367943659,0.38683824468201267,3.59525158154659,-0.34089288926430916,3.926946339483657,-1.3810415738737563,-0.5858198190406446,0.48964847025575964,-0.16372948749216756,0.007872098580347686,0.48964847025575964,0.8306316454399105,0.7361572254974664,1.434245143990909,1.3941514953495935,-3.598238387349531,0.688050566378247,3.4162772870291325,-0.16372948749216756,0.38683824468201267,0.33452611576463864,0.33452611576463864,-0.2812183777015856,-0.5236513396667263,3.744431287238993,0.2816075367943659,0.17394576765407171,1.434245143990909,1.1442885584140452,-0.4621081592112762,-0.04871252906513763,1.057240248022844,-0.10591263929674817,0.9681807864168185,-0.10591263929674817,0.11919997011538998,-0.4621081592112762,3.4391717680711436,-1.5224894117754426,0.7361572254974664,0.5900489466309929,3.7024803541208557,0.9228702829555585,0.5401492501085412,1.229406481355582,-0.04871252906513763,0.7836800160884329,0.33452611576463864,-0.6486147893595557,0.9681807864168185,0.48964847025575964,0.228081190180689,0.48964847025575964,0.8770244243066478,1.2712655154383892,0.5401492501085412,0.6393489264185823,0.17394576765407171,-0.7760889340064466,-0.5858198190406446,-0.6486147893595557,0.2816075367943659,0.5401492501085412,0.48964847025575964,0.4385452506124256,0.688050566378247,0.38683824468201267,0.6393489264185823,0.06384250748914849,-0.7120374352425395,-0.34089288926430916,1.8491689704918812,-0.7120374352425395,-0.04871252906513763,0.9228702829555585,1.2712655154383892,-0.04871252906513763,0.007872098580347686,0.33452611576463864,1.8491689704918812,0.2816075367943659,0.06384250748914849,0.4385452506124256,-0.7120374352425395,1.057240248022844,-0.4011890781327106,0.17394576765407171,0.4385452506124256,0.48964847025575964,0.4385452506124256,3.4162772870291325,-0.22216432068703482,-1.5224894117754426,1.1870839548927827,0.9228702829555585,-0.2812183777015856,-1.1736688722168886,0.228081190180689,0.17394576765407171,-0.5236513396667263 2937 Molecular transducer activity 11 28 3.8096195217173694 0.0001391808114241 O43813,O14786,Q99720,Q14108,P11717,Q8WTV0,O15118,Q9BUN8,P30536,Q15629,Q5KU26 Functions GO Molecular function msigdb_gomf 66,97,7,8,44,14,75,149,82,156,28 97,75,861,66,1345,797,44,152,82,2471,1047,1367,1152,484,1378,2482,8,156,310,542,28,14,1293,7,149,2185,698,1423 1.7035577277228184,1.9547430671585866,0.2816075367943659,2.090959820673029,0.007872098580347686,0.33452611576463864,2.94951498403428,1.229406481355582,1.8846964555914798,-0.6486147893595557,0.17394576765407171,0.007872098580347686,0.11919997011538998,0.5900489466309929,0.007872098580347686,-0.6486147893595557,4.712282471751374,1.229406481355582,0.8306316454399105,0.5401492501085412,3.681306413452911,4.192232038011874,0.06384250748914849,4.758390219688548,1.2712655154383892,-0.4011890781327106,0.4385452506124256,0.007872098580347686 2937 Transporter activity 48 147 3.7900505186472815 0.0001506166492191 Q96SU4,Q8IXU6,Q93050,P55011,O43772,P08183,Q8WTV0,Q99829,Q9Y487,P08195,O14975,Q9NS69,O60830,P49755,Q9UM00,P53985,P06576,Q15758,P12235,P21796,Q9H2D1,O43676,P51790,P24539,Q14728,O96008,O75947,P61916,Q14847,O75027,P11166,Q9Y6M7,O95342,O75964,O15118,P98194,P30536,Q99595,Q6NUK1,P19404,P04062,P56385,Q99808,P51798,Q13423,Q96GC9,Q9Y619,Q9HD20 Functions GO Molecular function msigdb_gomf 416,6,413,138,12,13,14,286,430,144,266,29,32,274,172,276,389,310,391,394,317,46,49,299,177,297,296,62,447,434,437,72,69,77,75,204,82,90,220,328,86,334,99,115,117,118,127,262 2518,2100,1433,1437,943,266,75,861,46,1443,12,862,32,434,1336,1446,709,1664,1570,296,77,2382,1788,2805,1452,2454,69,574,1789,297,2458,86,1895,1223,389,2304,1896,13,144,1581,2119,579,437,391,1458,438,1900,957,328,1686,1687,961,869,394,2023,299,2215,653,2216,82,807,2029,1692,967,2869,2127,1365,724,2743,480,274,2538,49,115,593,2641,1812,1922,276,138,2038,334,1149,1483,62,204,886,1604,2480,1261,1933,117,540,177,447,1382,541,310,671,1728,2334,2727,220,2339,608,752,6,2498,2160,758,549,614,14,1293,413,118,2561,685,416,1753,90,2733,99,286,1974,688,2074,1000,317,923,693,262,29,2918,1200,1422,1423,2782,1767,172,2708,2292,430,1776,127,72,1019 -0.7120374352425395,-0.4011890781327106,-0.04871252906513763,-0.04871252906513763,0.228081190180689,0.8770244243066478,1.9547430671585866,0.2816075367943659,2.8427159818750036,-0.04871252906513763,4.2103839880354075,0.2816075367943659,3.59525158154659,0.6393489264185823,0.007872098580347686,-0.04871252906513763,0.38683824468201267,-0.16372948749216756,-0.10591263929674817,0.8306316454399105,1.9547430671585866,-0.5858198190406446,-0.22216432068703482,-1.2421547136861633,-0.04871252906513763,-0.6486147893595557,2.057376685439682,0.48964847025575964,-0.22216432068703482,0.8306316454399105,-0.6486147893595557,1.8491689704918812,-0.2812183777015856,0.06384250748914849,0.688050566378247,-0.5236513396667263,-0.2812183777015856,4.192232038011874,1.2712655154383892,-0.10591263929674817,-0.4011890781327106,0.48964847025575964,0.6393489264185823,0.688050566378247,-0.04871252906513763,0.6393489264185823,-0.2812183777015856,0.228081190180689,0.7836800160884329,-0.16372948749216756,-0.16372948749216756,0.228081190180689,0.2816075367943659,0.688050566378247,-0.34089288926430916,0.8306316454399105,-0.4621081592112762,0.4385452506124256,-0.4621081592112762,1.8846964555914798,0.33452611576463864,-0.34089288926430916,-0.16372948749216756,0.228081190180689,-1.6665070292939557,-0.4011890781327106,0.007872098580347686,0.38683824468201267,-1.0386067543300004,0.5900489466309929,0.8770244243066478,-0.7120374352425395,2.618889115071512,1.473918375909616,0.48964847025575964,-0.8407704557687973,-0.22216432068703482,-0.2812183777015856,0.8770244243066478,1.3126701679029467,-0.34089288926430916,0.7836800160884329,0.11919997011538998,-0.04871252906513763,2.157214859958303,1.057240248022844,0.2816075367943659,-0.10591263929674817,-0.6486147893595557,0.06384250748914849,-0.2812183777015856,1.473918375909616,0.5401492501085412,1.1442885584140452,0.6393489264185823,0.007872098580347686,0.5401492501085412,0.8306316454399105,0.4385452506124256,-0.16372948749216756,-0.5236513396667263,-0.9720282133639213,1.0129671489863166,-0.5236513396667263,0.48964847025575964,0.38683824468201267,4.8486302687541105,-0.6486147893595557,-0.4011890781327106,0.38683824468201267,0.5401492501085412,0.48964847025575964,4.192232038011874,0.06384250748914849,0.688050566378247,1.473918375909616,-0.7120374352425395,0.4385452506124256,0.688050566378247,-0.16372948749216756,1.8491689704918812,-0.9720282133639213,1.7035577277228184,0.8770244243066478,-0.2812183777015856,0.4385452506124256,-0.34089288926430916,0.228081190180689,0.8306316454399105,0.2816075367943659,0.4385452506124256,0.9228702829555585,3.681306413452911,-2.9956170913795845,0.11919997011538998,0.007872098580347686,0.007872098580347686,-1.1058199287517425,-0.16372948749216756,1.1870839548927827,-0.906083163548422,-0.4621081592112762,0.688050566378247,-0.16372948749216756,1.434245143990909,2.057376685439682,0.228081190180689 2937 Abnormality of the lymphatic system 43 135 3.7802631079248 0.0001566627164097 P07602,P10253,Q92890,Q14108,Q14376,P38571,P15586,Q13428,Q10713,P04066,O75533,Q14739,P16278,P54802,Q9BT22,Q13510,Q6NUQ1,P10619,P07686,P61916,Q96HY6,P12955,Q15392,P11166,O95342,Q04446,O15118,O15460,Q01844,Q13426,P04062,P48735,P33991,Q99496,O75845,Q96BN8,O15160,P51798,O60762,Q9Y285,Q04721,P01889,P50851 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,129,411,8,147,17,20,540,538,30,518,35,37,42,316,55,449,58,61,62,346,187,71,437,69,443,75,200,442,337,86,216,330,96,212,374,467,115,228,119,484,120,362 1020,1563,1115,1329,75,467,200,228,707,1445,518,1890,212,948,1452,69,1892,2015,1221,1790,120,1894,86,30,1672,2206,1673,578,1127,3,61,1456,129,58,714,437,1033,2019,799,1034,187,581,800,20,37,2213,2681,961,523,802,2807,1586,804,586,653,1136,2469,330,2589,1142,1361,657,2314,17,2471,1803,1473,1590,1248,216,1367,725,362,1920,2037,115,1147,2225,1053,42,1054,2643,2396,1599,62,442,1932,443,484,2140,538,739,1156,337,540,2691,55,1718,826,8,147,35,1723,71,1835,603,449,750,2058,2753,2796,676,2159,1742,1289,2700,411,1294,374,346,1970,96,316,1540,2186,2914,2187,2188,1767,2093,119,1996,1319,1878,2711 0.17394576765407171,-0.10591263929674817,0.11919997011538998,0.007872098580347686,1.9547430671585866,0.5900489466309929,1.057240248022844,0.9681807864168185,0.38683824468201267,-0.04871252906513763,0.5401492501085412,-0.2812183777015856,1.0129671489863166,0.228081190180689,-0.04871252906513763,2.057376685439682,-0.2812183777015856,-0.34089288926430916,0.06384250748914849,-0.22216432068703482,1.434245143990909,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.16372948749216756,-0.4621081592112762,-0.16372948749216756,0.48964847025575964,0.11919997011538998,5.131894866624145,2.1898966319486153,-0.04871252906513763,1.3941514953495935,2.3177619175977977,0.38683824468201267,0.6393489264185823,0.17394576765407171,-0.34089288926430916,0.33452611576463864,0.17394576765407171,1.101010637080487,0.48964847025575964,0.33452611576463864,3.887244197186541,3.4162772870291325,-0.4621081592112762,-0.906083163548422,0.228081190180689,0.5401492501085412,0.33452611576463864,-1.2421547136861633,-0.10591263929674817,0.33452611576463864,0.48964847025575964,0.4385452506124256,0.11919997011538998,-0.6486147893595557,0.7836800160884329,-0.7760889340064466,0.11919997011538998,0.007872098580347686,0.4385452506124256,-0.5236513396667263,3.9856208887046614,-0.6486147893595557,-0.22216432068703482,-0.04871252906513763,-0.10591263929674817,0.06384250748914849,1.0129671489863166,0.007872098580347686,0.38683824468201267,0.7361572254974664,-0.2812183777015856,-0.34089288926430916,1.473918375909616,0.11919997011538998,-0.4621081592112762,0.17394576765407171,3.078582353860239,0.17394576765407171,-0.8407704557687973,-0.5858198190406446,-0.10591263929674817,2.157214859958303,0.6393489264185823,-0.2812183777015856,0.6393489264185823,0.5900489466309929,-0.4011890781327106,0.5401492501085412,0.38683824468201267,0.11919997011538998,0.7836800160884329,0.5401492501085412,-0.906083163548422,2.5014551385438826,-0.16372948749216756,0.33452611576463864,4.712282471751374,1.2712655154383892,3.4391717680711436,-0.16372948749216756,2.057376685439682,-0.22216432068703482,0.48964847025575964,0.6393489264185823,0.38683824468201267,-0.34089288926430916,-1.0386067543300004,-1.1736688722168886,0.4385452506124256,-0.4011890781327106,-0.16372948749216756,0.06384250748914849,-0.906083163548422,0.688050566378247,0.06384250748914849,0.7361572254974664,0.7836800160884329,-0.2812183777015856,1.7404982072045598,0.8306316454399105,-0.04871252906513763,-0.4011890781327106,-2.425443155290095,-0.4011890781327106,-0.4011890781327106,-0.16372948749216756,-0.34089288926430916,1.473918375909616,-0.2812183777015856,0.06384250748914849,-0.22216432068703482,-0.906083163548422 2937 Mental deterioration 17 93 3.751009405677336 0.0001761240918805 P07602,O75503,P16278,P20700,O60934,Q14108,Q9Y4U1,P54802,O15118,P06865,Q9BQE5,P50897,Q13510,P04062,P07686,P61916,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,4,37,133,186,8,248,42,75,16,23,22,55,86,61,62,95 1326,75,1443,706,1661,186,269,1446,4,2832,1668,1343,297,2458,1790,86,1576,1347,16,3,61,2118,2527,2305,714,1900,95,37,1035,1684,133,1688,802,1462,1235,2534,1690,359,967,2127,1245,875,1589,1695,22,1920,1249,971,42,1815,2478,62,1057,1062,443,736,2649,1490,538,2546,55,8,1065,2051,2335,987,1949,2410,1276,2921,913,410,1746,763,1853,498,997,2609,2173,2501,23,2901,246,1417,2866,2188,1010,2189,2845,1873,2622,430,248 0.007872098580347686,1.9547430671585866,-0.04871252906513763,0.38683824468201267,-0.16372948749216756,1.101010637080487,0.8770244243066478,-0.04871252906513763,4.878143286316388,-1.3810415738737563,-0.16372948749216756,0.007872098580347686,0.8306316454399105,-0.6486147893595557,-0.22216432068703482,1.8491689704918812,-0.10591263929674817,0.007872098580347686,4.024165938684547,5.131894866624145,2.1898966319486153,-0.4011890781327106,-0.7120374352425395,-0.5236513396667263,0.38683824468201267,-0.2812183777015856,1.7404982072045598,3.4162772870291325,0.17394576765407171,-0.16372948749216756,1.3536292924938709,-0.16372948749216756,0.33452611576463864,-0.04871252906513763,0.06384250748914849,-0.7120374352425395,-0.16372948749216756,0.7361572254974664,0.228081190180689,-0.4011890781327106,0.06384250748914849,0.2816075367943659,-0.10591263929674817,-0.16372948749216756,3.8063874677803375,-0.2812183777015856,0.06384250748914849,0.228081190180689,3.078582353860239,-0.22216432068703482,-0.6486147893595557,2.157214859958303,0.17394576765407171,0.17394576765407171,0.6393489264185823,0.38683824468201267,-0.8407704557687973,-0.04871252906513763,0.5401492501085412,-0.7120374352425395,2.5014551385438826,4.712282471751374,0.17394576765407171,-0.34089288926430916,-0.5236513396667263,0.228081190180689,-0.2812183777015856,-0.5858198190406446,0.06384250748914849,-3.510150275167924,0.2816075367943659,0.688050566378247,-0.16372948749216756,0.38683824468201267,-0.22216432068703482,0.5900489466309929,0.228081190180689,-0.7760889340064466,-0.4011890781327106,-0.6486147893595557,3.8063874677803375,-2.0378507439803,0.9681807864168185,0.007872098580347686,-1.5941764518204824,-0.4011890781327106,0.228081190180689,-0.4011890781327106,-1.451444818165324,-0.22216432068703482,-0.7760889340064466,0.688050566378247,0.9681807864168185 2937 Organelle subcompartment 104 319 3.7341965798147134 0.0001883153674047 Q99720,Q14108,Q5BJF2,O75844,Q9BQE5,Q15125,Q16850,Q14739,Q9UBM7,P07099,P11717,O43852,P35610,P67812,Q8IV08,Q15392,P24390,Q4J6C6,Q9H490,P04062,Q7Z2K6,O60725,O15127,Q96GC9,P51572,P01889,Q7Z7H5,P43307,Q8N511,P04439,Q969E2,Q9BUN8,P35613,Q15629,P20645,P30519,Q9UM00,P09601,Q9NX47,Q9H8Y8,Q96L58,Q86SZ2,Q6UWP7,O15260,Q9NQC3,P98194,Q8NFQ8,Q86UE4,O75915,O75845,P50402,Q96N66,Q99735,Q5J8M3,O60762,Q06136,Q10471,Q9Y282,Q9HD20,P61353,O94979,O14828,Q969V3,Q92538,Q969M3,O14975,O75122,P49257,P49755,P51648,Q8N0U8,Q9BT22,Q14165,Q13190,P50570,Q96HY6,Q16799,Q9P2W9,Q15363,O95674,Q12907,P09496,P37268,Q9Y320,Q15041,Q8TBA6,Q9BVK6,Q96A57,Q92890,Q9Y296,Q8TEM1,Q9Y678,P61006,O43795,Q5VYK3,Q07065,Q86XL3,Q6NUQ1,Q969N2,O94874,Q9BTU6,Q5VV42,Q9BU23,Q9H3N1 Localization GO Cellular component msigdb_gocc 7,8,11,19,23,26,27,35,38,39,44,47,53,59,63,71,74,85,91,86,98,102,113,118,122,120,124,121,131,128,135,149,145,156,152,153,172,173,198,197,196,194,192,185,208,204,223,222,213,212,217,242,243,239,228,234,235,264,262,252,250,249,285,283,284,266,268,272,274,275,313,316,309,306,303,346,340,351,339,323,336,326,332,379,369,373,418,414,411,425,409,432,395,385,405,401,452,449,453,436,500,491,501,503 565,465,1559,1325,1326,1563,1778,2102,2447,249,1209,860,266,2579,113,185,1022,2198,2581,789,1212,2105,385,47,2379,1118,102,228,1335,268,517,1024,1219,2010,19,212,213,2832,436,1786,1573,2524,250,572,1342,1669,1343,951,2203,323,795,796,2457,1790,120,86,128,519,641,952,39,1455,2526,326,798,173,2119,2923,44,1229,1352,957,2632,1231,152,1905,2023,1232,74,1354,804,805,1796,1356,1909,153,806,1138,2861,1141,53,145,332,2869,1363,1243,588,121,1247,591,1591,2391,2034,480,272,274,217,303,1919,1810,122,275,1052,2132,532,2134,1924,1147,2478,1925,2227,2541,2720,2543,1599,395,729,1373,972,252,1256,1483,883,1601,1705,2809,2877,2400,59,1603,204,1062,735,1931,484,234,401,1263,2721,235,823,538,1264,336,1608,306,1719,1498,2653,826,8,309,2238,2146,35,982,1382,1830,2597,2852,369,2775,1613,26,1725,339,1164,71,745,156,2054,1271,340,27,2599,85,489,11,239,986,2337,491,405,2491,1511,449,1274,2339,904,192,98,124,194,222,547,452,1078,63,2496,2921,313,911,2498,131,679,913,914,1516,2159,2256,223,2907,2163,614,373,2257,1850,2164,680,409,1288,551,1178,283,1083,837,761,411,135,284,453,285,1294,414,2423,1963,118,838,346,996,196,242,2067,685,2173,7,243,2734,2759,23,2900,2072,1533,316,500,501,149,1535,1406,418,999,1408,1000,1638,2428,503,91,2430,197,2434,2572,262,1411,208,2280,927,198,2088,696,2187,630,2616,698,351,1311,38,1423,2763,933,1768,1770,172,935,1012,264,425,379,2098,2576,2293,2710,2802,1320,2001,2786,432,2371,2623,1558 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2937 Secondary alcohol metabolic process 10 39 3.716430631815963 0.0002020570829814 Q14739,Q9UBM7,Q15392,Q8WTV0,O15118,Q9BQE5,P35610,Q15125,Q16850,P61916 Processes and pathways GO Biological process msigdb_gobp 35,38,71,14,75,23,53,26,27,62 75,386,212,948,1573,2457,86,799,521,1352,2462,53,332,2472,2391,216,2744,2591,878,1701,62,1375,1709,1932,1936,827,2146,35,1382,26,1833,71,2054,27,14,2502,23,38,377 1.9547430671585866,0.688050566378247,1.0129671489863166,0.228081190180689,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.33452611576463864,0.5401492501085412,0.007872098580347686,-0.6486147893595557,2.589890921013961,0.7836800160884329,-0.6486147893595557,-0.5858198190406446,1.0129671489863166,-1.0386067543300004,-0.7760889340064466,0.2816075367943659,-0.16372948749216756,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,4.192232038011874,-0.6486147893595557,3.8063874677803375,3.4162772870291325,0.7361572254974664 2937 Azurophil granule lumen 11 35 3.652616435746303 0.0002595818287041 P16278,Q9H7Z7,P15586,Q9BTY2,Q92820,P15289,P61916,P10619,P07686,P04066,P06280 Localization GO Cellular component msigdb_gocc 37,181,20,52,54,95,62,58,61,30,31 1443,2457,30,31,2304,1580,61,58,2528,95,20,37,872,1466,812,1479,1701,203,2478,1703,62,1151,1489,2690,669,1518,54,1963,686,2351,52,1098,181,2829,1013 -0.04871252906513763,-0.6486147893595557,3.6169723053440874,3.6169723053440874,-0.5236513396667263,-0.10591263929674817,2.1898966319486153,2.3177619175977977,-0.7120374352425395,1.7404982072045598,3.887244197186541,3.4162772870291325,0.2816075367943659,-0.04871252906513763,0.33452611576463864,-0.04871252906513763,-0.16372948749216756,1.057240248022844,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.11919997011538998,-0.04871252906513763,-0.906083163548422,0.4385452506124256,-0.04871252906513763,2.5311775269119203,-0.2812183777015856,0.4385452506124256,-0.5236513396667263,2.618889115071512,0.17394576765407171,1.1442885584140452,-1.311278575581721,0.228081190180689 2937 Golgi membrane 40 112 3.611497650455105 0.0003044338427231 Q9BVK6,P04439,Q92896,Q14108,Q92538,Q9Y296,Q6ZRP7,P35613,Q9Y678,P49257,P49755,Q9UM00,P11717,Q9H7Z7,P51790,Q13190,Q9H8Y8,Q96L58,Q8IV08,P50570,Q16799,Q15392,O15260,O95342,Q7LGA3,P24390,Q8N6T3,O43505,P98194,Q9P2W9,Q15363,Q9Y3E0,Q12907,O15258,Q10471,Q8TBA6,O15498,P51572,Q9Y282,P01889 Localization GO Cellular component msigdb_gocc 418,128,412,8,283,425,148,145,432,272,274,172,44,181,49,306,197,196,63,303,340,71,185,69,344,74,345,76,204,351,339,226,336,322,235,373,227,122,264,120 2518,2102,1115,2579,322,185,227,76,2377,2105,1335,1219,572,1342,69,794,1790,120,128,2526,2119,2923,437,44,2023,74,1141,145,2898,1243,588,1591,480,272,274,303,122,49,2132,532,2134,1924,2541,2543,1599,395,1373,972,1601,1059,204,484,1263,2721,235,823,538,336,306,8,982,1723,1725,339,1164,71,745,1271,340,148,344,1172,1736,63,2498,345,2161,2256,614,373,1741,1288,283,412,196,685,1535,418,2798,1408,1002,2430,181,197,2781,927,2088,2616,351,1311,1107,1551,1770,172,264,425,2442,2875,634,2293,226,432 -0.7120374352425395,-0.4011890781327106,0.11919997011538998,-0.7760889340064466,0.7836800160884329,1.101010637080487,0.9681807864168185,1.9547430671585866,-0.5858198190406446,-0.4011890781327106,0.007872098580347686,0.06384250748914849,0.48964847025575964,0.007872098580347686,2.057376685439682,0.33452611576463864,-0.22216432068703482,1.434245143990909,1.3941514953495935,-0.7120374352425395,-0.4011890781327106,-3.598238387349531,0.6393489264185823,2.94951498403428,-0.34089288926430916,1.9892736116862897,0.11919997011538998,1.2712655154383892,-2.0378507439803,0.06384250748914849,0.48964847025575964,-0.10591263929674817,0.5900489466309929,0.8770244243066478,0.8770244243066478,0.8306316454399105,1.434245143990909,2.618889115071512,-0.4011890781327106,0.5401492501085412,-0.4011890781327106,-0.2812183777015856,-0.7120374352425395,-0.7120374352425395,-0.10591263929674817,0.688050566378247,0.007872098580347686,0.228081190180689,-0.10591263929674817,0.17394576765407171,1.057240248022844,0.5900489466309929,0.06384250748914849,-0.9720282133639213,0.9681807864168185,0.33452611576463864,0.5401492501085412,0.7836800160884329,0.8306316454399105,4.712282471751374,0.228081190180689,-0.16372948749216756,-0.16372948749216756,0.7836800160884329,0.11919997011538998,2.057376685439682,0.38683824468201267,0.06384250748914849,0.7836800160884329,1.2712655154383892,0.7836800160884329,0.11919997011538998,-0.16372948749216756,2.157214859958303,-0.6486147893595557,0.7836800160884329,-0.4011890781327106,-0.4621081592112762,0.48964847025575964,0.7361572254974664,-0.16372948749216756,0.06384250748914849,0.8770244243066478,0.688050566378247,1.101010637080487,0.4385452506124256,-0.04871252906513763,0.688050566378247,-1.1736688722168886,0.007872098580347686,0.228081190180689,-0.5858198190406446,1.1442885584140452,1.101010637080487,-1.1058199287517425,0.2816075367943659,-0.34089288926430916,-0.7760889340064466,0.7836800160884329,0.06384250748914849,0.17394576765407171,-0.04871252906513763,-0.16372948749216756,1.1870839548927827,0.9228702829555585,0.688050566378247,-0.5858198190406446,-1.6665070292939557,0.48964847025575964,-0.4621081592112762,1.0129671489863166,0.688050566378247 2937 Alpha/Beta hydrolase fold [IPR029058] 8 22 3.599681706760319 0.0003186069320608 Q9HB40,Q9H3G5,P42785,P07099,Q8NCC3,P38571,P50897,P10619 Sequence InterPro Superfamily interpro_homologous_superfamily 0,1,5,39,15,17,22,58 1447,39,58,2716,582,17,5,2130,1367,22,85,904,2415,911,15,1528,1,1300,0,2183,2670,2577 -0.04871252906513763,3.3700219703880934,2.3177619175977977,-0.9720282133639213,0.48964847025575964,3.9856208887046614,4.863421508907323,-0.4011890781327106,0.007872098580347686,3.8063874677803375,1.8846964555914798,0.2816075367943659,-0.5858198190406446,0.2816075367943659,4.0999276525600274,-0.04871252906513763,5.830215713580066,0.06384250748914849,5.893957451831641,-0.4011890781327106,-0.8407704557687973,-0.7120374352425395 2937 Vascular process in circulatory system 10 27 3.5872536689559147 0.0003341791840891 Q9HB40,Q99808,P53985,O94813,Q96AC1,Q07157,P55011,P02786,P08183,P42892 Processes and pathways GO Biological process msigdb_gobp 0,99,276,68,241,255,138,41,13,25 1563,1437,1118,1450,68,41,1346,13,437,1686,807,25,1248,1915,1145,276,138,1256,366,255,1715,1163,310,2339,241,99,0 -0.10591263929674817,-0.04871252906513763,0.11919997011538998,-0.04871252906513763,2.057376685439682,3.1288971739076072,0.007872098580347686,4.192232038011874,0.6393489264185823,-0.16372948749216756,0.33452611576463864,3.744431287238993,0.06384250748914849,-0.2812183777015856,0.11919997011538998,0.8770244243066478,1.3126701679029467,0.06384250748914849,0.7361572254974664,0.9228702829555585,-0.16372948749216756,0.11919997011538998,0.8306316454399105,-0.5236513396667263,0.9681807864168185,1.7035577277228184,5.893957451831641 2937 Transport 97 424 3.580771953815823 0.0003425805634569 Q8IXU6,Q99720,O43772,P08183,Q9BQE5,Q9NS69,O60830,P11717,O43676,P51790,P61916,Q9Y6M7,O95342,A0AVF1,P24390,O75964,O15118,Q99595,Q8N4H5,O14949,Q99808,Q16881,O15127,P51798,P51572,Q9BZI7,Q9Y619,Q7Z7H5,Q969E2,P55011,Q9BTX1,Q9BUN8,P08195,O60826,Q15629,P20645,O43169,Q9UM00,Q14728,P98194,Q9Y3E0,Q6NUK1,O43592,O15498,Q9Y282,Q9UN86,Q9HD20,Q15286,O94979,O14828,Q92538,Q969M3,O15397,O75165,P49257,P49755,P53985,Q15758,Q7Z3U7,Q9H2D1,Q9H4M9,Q9NVZ3,Q13190,P24539,O60493,O96008,O75947,Q8N6T3,Q9UNH7,Q9P2W9,Q15363,Q12907,P19404,P56385,O43491,Q9BVK6,Q96SU4,Q93050,Q9Y296,Q8TEM1,Q9Y487,Q9Y678,Q8N1F7,P61006,P06576,P12235,P21796,P82979,Q96A65,Q6NUQ1,Q9Y5L4,Q14847,O75027,P11166,Q96QK1,Q6DKK2,Q9H269 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 6,7,12,13,23,29,32,44,46,49,62,72,69,73,74,77,75,90,92,94,99,111,113,115,122,125,127,124,135,138,140,149,144,143,156,152,150,172,177,204,226,220,211,227,264,263,262,256,250,249,283,284,267,269,272,274,276,310,311,317,318,320,306,299,293,297,296,345,352,351,339,336,328,334,353,418,416,413,425,409,430,432,408,395,389,391,394,400,455,449,463,447,434,437,498,492,502 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2937 Endocytosis 20 94 3.5783185111634457 0.000345811871609 Q14108,Q9NZQ3,Q8WTV0,Q08380,P50897,Q5KU26,O75165,P20645,P02786,P11717,Q9H4M9,Q9NVZ3,P51790,P50570,O15260,Q8N6T3,O15118,P09496,Q5VW38,Q9Y5K6 Processes and pathways GO Biological process msigdb_gobp 8,142,14,18,22,28,269,152,41,44,318,320,49,303,185,345,75,326,88,382 565,1207,1326,1563,2373,75,185,2105,570,269,1571,2114,1670,41,797,2304,326,798,44,439,2631,2632,2022,716,152,1586,871,805,872,655,1140,587,659,303,22,1143,1051,49,1052,2899,1599,2229,1059,1708,818,1603,2480,1062,1489,1490,18,1497,1158,2750,2653,8,1827,367,1267,1725,2055,2334,986,28,88,1169,1624,345,2160,2889,14,1747,998,2173,2174,1531,1638,1538,318,320,506,142,1009,2782,1551,1554,1770,1316,702,2708,1202,1014,382,2001 0.48964847025575964,0.06384250748914849,0.007872098580347686,-0.10591263929674817,-0.5858198190406446,1.9547430671585866,1.101010637080487,-0.4011890781327106,0.48964847025575964,0.8770244243066478,-0.10591263929674817,-0.4011890781327106,-0.16372948749216756,3.1288971739076072,0.33452611576463864,-0.5236513396667263,0.7836800160884329,0.33452611576463864,2.94951498403428,0.6393489264185823,-0.8407704557687973,-0.8407704557687973,-0.34089288926430916,0.38683824468201267,1.229406481355582,-0.10591263929674817,0.2816075367943659,0.33452611576463864,0.2816075367943659,0.4385452506124256,0.11919997011538998,0.48964847025575964,0.4385452506124256,0.8306316454399105,3.8063874677803375,0.11919997011538998,0.17394576765407171,2.618889115071512,0.17394576765407171,-2.0378507439803,-0.10591263929674817,-0.4621081592112762,0.17394576765407171,-0.16372948749216756,0.33452611576463864,-0.10591263929674817,-0.6486147893595557,0.17394576765407171,-0.04871252906513763,-0.04871252906513763,3.9661781891098036,-0.04871252906513763,0.11919997011538998,-1.0386067543300004,-0.8407704557687973,4.712282471751374,-0.22216432068703482,0.7361572254974664,0.06384250748914849,-0.16372948749216756,-0.34089288926430916,-0.5236513396667263,0.228081190180689,3.681306413452911,1.8491689704918812,0.11919997011538998,-0.10591263929674817,0.7836800160884329,-0.4011890781327106,-1.8873708060077286,4.192232038011874,-0.16372948749216756,0.228081190180689,-0.4011890781327106,-0.4011890781327106,-0.04871252906513763,-0.10591263929674817,-0.04871252906513763,0.8306316454399105,0.8306316454399105,0.5900489466309929,1.3126701679029467,0.228081190180689,-1.1058199287517425,-0.04871252906513763,-0.04871252906513763,-0.16372948749216756,0.06384250748914849,0.4385452506124256,-0.906083163548422,0.11919997011538998,0.228081190180689,0.7361572254974664,-0.2812183777015856 2937 Abnormal circulating lipid concentration 22 71 3.565901969408193 0.0003626069061504 Q9BTV4,Q8N511,P07602,O43772,P38571,O75844,Q15125,P06280,P49257,Q14739,Q9UBM7,P40855,P56589,P61916,Q15392,Q13426,P37268,O75845,P50402,Q9Y4U1,Q9Y285,Q10471 Drugs and Diseases Human Phenotype Ontology msigdb_hp 258,131,3,12,17,19,26,31,272,35,38,164,174,62,71,337,332,212,217,248,119,235 942,705,12,2009,1783,19,212,1343,355,1894,31,712,3,1676,1584,2463,718,586,1038,2469,2684,1801,2741,332,17,164,1244,875,2222,272,2744,217,877,1920,2037,1053,2540,174,1598,62,1150,1262,235,445,337,980,35,1503,26,71,2054,1068,2844,131,1519,1178,453,2856,258,2277,2360,2188,38,2287,1767,119,938,2802,248,2905,2623 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2937 Endoplasmic reticulum golgi intermediate compartment 20 40 3.55419243449922 0.0003791416860983 Q9BVK6,Q8N511,Q92538,Q9Y678,P49257,P49755,Q02818,P80303,Q13190,O15260,P24390,Q15363,P53634,Q12907,O15258,O15498,Q96GC9,P51572,Q9Y282,Q7Z7H5 Localization GO Cellular component msigdb_gocc 418,131,283,432,272,274,40,50,306,185,74,339,203,336,322,227,118,122,264,124 322,185,227,1219,572,1674,954,74,804,655,272,274,970,122,2134,203,50,40,2721,336,306,982,1613,339,405,124,1279,131,283,2265,118,2072,418,628,1311,1107,264,2293,432,636 0.7836800160884329,1.101010637080487,0.9681807864168185,0.06384250748914849,0.48964847025575964,-0.16372948749216756,0.228081190180689,1.9892736116862897,0.33452611576463864,0.4385452506124256,0.8770244243066478,0.8770244243066478,0.228081190180689,1.434245143990909,-0.4011890781327106,1.057240248022844,2.618889115071512,3.17849140779286,-0.9720282133639213,0.7836800160884329,0.8306316454399105,0.228081190180689,-0.10591263929674817,0.7836800160884329,0.688050566378247,1.434245143990909,0.06384250748914849,1.3941514953495935,0.8770244243066478,-0.4621081592112762,1.473918375909616,-0.34089288926430916,0.688050566378247,0.48964847025575964,0.06384250748914849,0.17394576765407171,0.9228702829555585,-0.4621081592112762,0.688050566378247,0.48964847025575964 2937 Recurrent respiratory infections 25 111 3.5144161649683814 0.0004407217598589 P07602,P10253,Q00577,P20700,Q9Y487,P15586,O60826,P26038,P04066,P16278,Q16851,P02786,P54802,P09601,Q13510,P12955,O60934,Q6NW34,O15460,P53634,P04062,P33991,P51798,P01889,P50851 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,129,254,133,430,20,143,270,30,37,168,41,42,173,55,187,186,343,200,203,86,330,115,120,362 1020,1021,1115,942,2003,200,143,707,186,1445,1787,1452,388,1892,1027,2015,1221,1790,120,41,86,30,1127,1454,3,173,2459,129,2019,1898,187,581,800,1585,20,37,1684,1794,133,2461,1905,651,270,1463,872,1136,330,2684,2471,529,1473,2536,1248,362,726,1249,115,1922,1813,203,2225,42,1054,2745,594,2647,1150,2232,254,1931,484,2748,1607,1156,55,1718,1162,1503,1163,1944,1165,2693,168,1948,1510,343,2699,2753,676,1285,993,1181,1852,1399,1749,1859,2428,1864,1982,1539,2085,2186,2188,2189,933,2287,1314,2672,430,938,2802 0.17394576765407171,0.17394576765407171,0.11919997011538998,0.228081190180689,-0.34089288926430916,1.057240248022844,1.2712655154383892,0.38683824468201267,1.101010637080487,-0.04871252906513763,-0.22216432068703482,-0.04871252906513763,0.688050566378247,-0.2812183777015856,0.17394576765407171,-0.34089288926430916,0.06384250748914849,-0.22216432068703482,1.434245143990909,3.1288971739076072,1.8491689704918812,3.6169723053440874,0.11919997011538998,-0.04871252906513763,5.131894866624145,1.1442885584140452,-0.6486147893595557,1.3941514953495935,-0.34089288926430916,-0.2812183777015856,1.101010637080487,0.48964847025575964,0.33452611576463864,-0.10591263929674817,3.887244197186541,3.4162772870291325,-0.16372948749216756,-0.22216432068703482,1.3536292924938709,-0.6486147893595557,-0.2812183777015856,0.4385452506124256,0.8770244243066478,-0.04871252906513763,0.2816075367943659,0.11919997011538998,0.7836800160884329,-0.906083163548422,-0.6486147893595557,0.5401492501085412,-0.04871252906513763,-0.7120374352425395,0.06384250748914849,0.7361572254974664,0.38683824468201267,0.06384250748914849,1.473918375909616,-0.2812183777015856,-0.22216432068703482,1.057240248022844,-0.4621081592112762,3.078582353860239,0.17394576765407171,-1.0386067543300004,0.48964847025575964,-0.8407704557687973,0.11919997011538998,-0.4621081592112762,0.9228702829555585,-0.2812183777015856,0.5900489466309929,-1.0386067543300004,-0.10591263929674817,0.11919997011538998,2.5014551385438826,-0.16372948749216756,0.11919997011538998,-0.04871252906513763,0.11919997011538998,-0.2812183777015856,0.11919997011538998,-0.906083163548422,1.1870839548927827,-0.2812183777015856,-0.04871252906513763,0.7836800160884329,-0.906083163548422,-1.0386067543300004,0.4385452506124256,0.06384250748914849,0.228081190180689,0.11919997011538998,-0.22216432068703482,0.007872098580347686,-0.16372948749216756,-0.22216432068703482,-0.5858198190406446,-0.22216432068703482,-0.2812183777015856,-0.04871252906513763,-0.34089288926430916,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,0.2816075367943659,-0.4621081592112762,0.06384250748914849,-0.8407704557687973,0.688050566378247,0.2816075367943659,-1.1736688722168886 2937 Lipid binding 20 117 3.474073466394594 0.0005126206575014 Q15286,P07602,Q14108,Q92538,Q8WTV0,Q8NCC3,Q9BQE5,P50897,O14773,P11717,P35610,P56589,P61916,O15118,P30536,Q9H490,P04062,P46940,Q96AC1,Q9NQZ5 Functions GO Molecular function msigdb_gomf 256,3,8,283,14,15,23,22,24,44,53,174,62,75,82,91,86,215,241,246 565,1325,1207,1326,1563,2447,24,75,861,2376,1439,789,385,1661,293,570,1120,1573,2114,86,2680,1345,1895,2304,3,2385,1896,954,2586,1457,1033,44,2210,1231,523,394,2023,2634,2312,586,2532,1798,82,331,53,1471,2869,1365,2390,215,480,22,1480,2133,1596,532,2478,2642,174,2320,62,2399,886,1375,596,1153,445,1497,742,1158,8,1382,1723,1832,256,2601,753,1624,1954,1513,15,2555,14,283,761,241,1747,1749,416,998,2070,286,1531,1858,23,1533,1407,2074,1000,91,2430,246,2359,2188,1009,1768,2090,1554,702,2708,352,1428,634,787,2919,2711,2001 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2937 Abnormal vertebral morphology 20 102 3.4524224130356185 0.0005555772276899 Q14108,P15586,O60826,Q15125,P04066,Q9UM00,Q14739,P16278,Q9UBM7,P54802,P10619,Q96L58,Q9UBN7,Q32P28,Q6NUK1,P04062,P48735,Q96AY3,P51798,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 8,20,143,26,30,172,35,37,38,42,58,196,210,80,220,86,216,105,115,127 939,1778,942,1438,1334,2451,1118,143,1663,2299,212,948,1452,575,2015,1790,86,30,1674,58,714,2868,20,37,1352,646,961,1905,523,2531,2929,964,1468,2684,2898,527,2315,333,2885,1590,216,970,115,2640,42,1598,594,2229,2400,1150,1823,2042,1931,484,538,445,1156,2691,8,35,983,1503,26,1269,745,2054,80,986,1510,220,449,1949,343,1735,2844,1174,1280,1515,2161,1742,105,1852,346,196,1968,1091,1982,1986,2182,851,1766,38,210,1108,2287,172,1649,2621,2709,2802,1878,127 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2937 Abnormality of the vasculature of the eye 11 67 3.412785654657108 0.0006430249649567 Q14739,P07602,P16278,P02786,P06865,Q13510,P10619,P01889,P07686,P04066,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,3,37,41,16,55,58,120,61,30,31 1881,2738,945,386,707,1446,1448,2628,120,41,30,128,1673,31,16,3,61,2017,58,2211,1459,37,1684,1794,523,1688,802,1463,586,1356,2534,2683,1360,2684,2898,1469,2869,2742,1367,2591,1478,362,1147,1150,1261,1932,823,1715,2691,55,1501,35,1503,1836,674,2159,1960,2262,2700,1746,411,685,2182,2187,2188,2287,2802 -0.2812183777015856,-1.0386067543300004,0.228081190180689,0.688050566378247,0.38683824468201267,-0.04871252906513763,-0.04871252906513763,-0.8407704557687973,1.434245143990909,3.1288971739076072,3.6169723053440874,1.3941514953495935,-0.16372948749216756,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,-0.34089288926430916,2.3177619175977977,-0.4621081592112762,-0.04871252906513763,3.4162772870291325,-0.16372948749216756,-0.22216432068703482,0.5401492501085412,-0.16372948749216756,0.33452611576463864,-0.04871252906513763,0.48964847025575964,0.007872098580347686,-0.7120374352425395,-0.906083163548422,0.007872098580347686,-0.906083163548422,-2.0378507439803,-0.04871252906513763,-1.6665070292939557,-1.0386067543300004,0.007872098580347686,-0.7760889340064466,-0.04871252906513763,0.7361572254974664,0.11919997011538998,0.11919997011538998,0.06384250748914849,-0.2812183777015856,0.33452611576463864,-0.16372948749216756,-0.906083163548422,2.5014551385438826,-0.04871252906513763,3.4391717680711436,-0.04871252906513763,-0.22216432068703482,0.4385452506124256,-0.4011890781327106,-0.2812183777015856,-0.4621081592112762,-0.906083163548422,-0.16372948749216756,0.688050566378247,0.4385452506124256,-0.4011890781327106,-0.4011890781327106,-0.4011890781327106,-0.4621081592112762,-1.1736688722168886 2937 Glycosphingolipid metabolism 8 14 3.4069912842008256 0.0006568322442981 P07602,P16278,P06865,Q13510,P10619,P04062,P07686,P06280 Processes and pathways Reactome Pathways msigdb_reactome 3,37,16,55,58,86,61,31 565,1443,86,31,16,3,61,58,95,37,55,1533,2088,2188 0.48964847025575964,-0.04871252906513763,1.8491689704918812,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,2.3177619175977977,1.7404982072045598,3.4162772870291325,2.5014551385438826,-0.04871252906513763,-0.34089288926430916,-0.4011890781327106 2937 Sphingolipid metabolic process 10 24 3.404614285756211 0.0006625756861169 P07602,P16278,Q99805,Q8NCC3,P06865,P50897,Q13510,P04062,P07686,P06280 Processes and pathways GO Biological process msigdb_gobp 3,37,207,15,16,22,55,86,61,31 1022,2198,1343,86,31,16,3,61,37,2023,1237,22,234,1936,55,2487,679,15,207,2088,696,2188,630,2616 0.17394576765407171,-0.4621081592112762,0.007872098580347686,1.8491689704918812,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,3.4162772870291325,-0.34089288926430916,0.06384250748914849,3.8063874677803375,0.9681807864168185,-0.2812183777015856,2.5014551385438826,-0.6486147893595557,0.4385452506124256,4.0999276525600274,1.057240248022844,-0.34089288926430916,0.4385452506124256,-0.4011890781327106,0.48964847025575964,-0.7760889340064466 2937 Sphingolipid metabolism 8 23 3.393247260559367 0.0006906926242493 P07602,P16278,P06865,Q13510,P10619,P04062,P07686,P06280 Processes and pathways Reactome Pathways msigdb_reactome 3,37,16,55,58,86,61,31 565,1022,2198,1443,1669,1343,86,31,16,3,61,58,95,37,2023,275,234,55,679,1533,2088,2188,2616 0.48964847025575964,0.17394576765407171,-0.4621081592112762,-0.04871252906513763,-0.16372948749216756,0.007872098580347686,1.8491689704918812,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,2.3177619175977977,1.7404982072045598,3.4162772870291325,-0.34089288926430916,0.8770244243066478,0.9681807864168185,2.5014551385438826,0.4385452506124256,-0.04871252906513763,-0.34089288926430916,-0.4011890781327106,-0.7760889340064466 2937 Hydrolase activity acting on glycosyl bonds 9 28 3.386174876284447 0.0007087420322495 O75503,P16278,P54802,P06865,Q9BTY2,P04062,P07686,P04066,P06280 Functions GO Molecular function msigdb_gomf 4,37,42,16,52,86,61,30,31 469,2006,4,86,30,31,16,61,129,2211,581,37,585,2682,2833,1801,42,2041,443,826,1265,1271,905,2729,52,2183,1007,2093 0.5900489466309929,-0.34089288926430916,4.878143286316388,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,2.1898966319486153,1.3941514953495935,-0.4621081592112762,0.48964847025575964,3.4162772870291325,0.48964847025575964,-0.906083163548422,-1.3810415738737563,-0.22216432068703482,3.078582353860239,-0.34089288926430916,0.6393489264185823,0.33452611576463864,0.06384250748914849,0.06384250748914849,0.2816075367943659,-0.9720282133639213,2.618889115071512,-0.4011890781327106,0.228081190180689,-0.34089288926430916 2937 Alcohol metabolic process 15 73 3.37494882825187 0.0007382941751974 O75845,Q14739,Q9UBM7,Q15392,P04062,Q8WTV0,O15118,Q9BQE5,P35610,Q13510,P61916,Q15125,Q16850,P48735,P17174 Processes and pathways GO Biological process msigdb_gobp 212,35,38,71,86,14,75,23,53,55,62,26,27,216,151 1206,75,1022,2198,1333,386,228,212,948,1573,2014,1125,2457,86,2525,799,2210,521,2120,1230,1352,151,2462,2834,1043,53,332,2472,1474,2391,216,2744,2591,878,1920,1249,275,1701,2396,2822,62,1375,1709,1932,538,1936,55,2750,827,2146,35,1382,26,1833,71,2054,2333,27,746,1511,1516,2255,2257,14,2562,2609,2502,23,2081,1418,38,377,2098 0.06384250748914849,1.9547430671585866,0.17394576765407171,-0.4621081592112762,0.007872098580347686,0.688050566378247,0.9681807864168185,1.0129671489863166,0.228081190180689,-0.10591263929674817,-0.34089288926430916,0.11919997011538998,-0.6486147893595557,1.8491689704918812,-0.7120374352425395,0.33452611576463864,-0.4621081592112762,0.5401492501085412,-0.4011890781327106,0.06384250748914849,0.007872098580347686,1.229406481355582,-0.6486147893595557,-1.3810415738737563,0.17394576765407171,2.589890921013961,0.7836800160884329,-0.6486147893595557,-0.04871252906513763,-0.5858198190406446,1.0129671489863166,-1.0386067543300004,-0.7760889340064466,0.2816075367943659,-0.2812183777015856,0.06384250748914849,0.8770244243066478,-0.16372948749216756,-0.5858198190406446,-1.311278575581721,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,0.5401492501085412,-0.2812183777015856,2.5014551385438826,-1.0386067543300004,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,-0.5236513396667263,3.7024803541208557,0.38683824468201267,-0.04871252906513763,-0.04871252906513763,-0.4621081592112762,-0.4621081592112762,4.192232038011874,-0.7120374352425395,-0.7760889340064466,-0.6486147893595557,3.8063874677803375,-0.34089288926430916,0.007872098580347686,3.4162772870291325,0.7361572254974664,-0.34089288926430916 2937 Weight loss 13 71 3.373981515481134 0.0007408934262369 Q99496,P07602,O60934,Q99720,O15460,P38571,O75844,P35610,Q13423,Q06136,P42892,P04062,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,3,186,7,200,17,19,53,117,234,25,86,120 1332,200,186,269,19,796,120,1894,86,2206,1127,1454,3,2017,714,1584,1684,1794,523,1688,1586,2466,804,2534,53,359,2741,1469,2314,17,2471,2742,875,25,968,1590,1367,1478,1249,1146,971,1054,2479,442,1261,736,234,739,117,2691,598,1065,1723,603,2056,1731,2058,1276,2753,2159,1289,1746,498,96,7,1538,1766,2187,2188,2285,1873 0.007872098580347686,1.057240248022844,1.101010637080487,0.8770244243066478,3.926946339483657,0.33452611576463864,1.434245143990909,-0.2812183777015856,1.8491689704918812,-0.4621081592112762,0.11919997011538998,-0.04871252906513763,5.131894866624145,-0.34089288926430916,0.38683824468201267,-0.10591263929674817,-0.16372948749216756,-0.22216432068703482,0.5401492501085412,-0.16372948749216756,-0.10591263929674817,-0.6486147893595557,0.33452611576463864,-0.7120374352425395,2.589890921013961,0.7361572254974664,-1.0386067543300004,-0.04871252906513763,-0.5236513396667263,3.9856208887046614,-0.6486147893595557,-1.0386067543300004,0.2816075367943659,3.744431287238993,0.228081190180689,-0.10591263929674817,0.007872098580347686,-0.04871252906513763,0.06384250748914849,0.11919997011538998,0.228081190180689,0.17394576765407171,-0.6486147893595557,0.6393489264185823,0.06384250748914849,0.38683824468201267,0.9681807864168185,0.38683824468201267,1.473918375909616,-0.906083163548422,0.48964847025575964,0.17394576765407171,-0.16372948749216756,0.48964847025575964,-0.34089288926430916,-0.16372948749216756,-0.34089288926430916,0.06384250748914849,-1.0386067543300004,-0.4011890781327106,0.06384250748914849,-0.16372948749216756,0.5900489466309929,1.7404982072045598,4.758390219688548,-0.04871252906513763,-0.16372948749216756,-0.4011890781327106,-0.4011890781327106,-0.4621081592112762,-0.22216432068703482 2937 Glycosidase 8 16 3.370044593154275 0.000751560202483 P16278,P54802,P06865,Q9BTY2,P04062,P07686,P04066,P06280 Functions Protein Atlas Molecular function protein_atlas_molecular_function 37,42,16,52,86,61,30,31 469,2006,86,30,31,16,61,129,37,1801,42,2041,826,1265,1271,52 0.5900489466309929,-0.34089288926430916,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,2.1898966319486153,1.3941514953495935,3.4162772870291325,-0.22216432068703482,3.078582353860239,-0.34089288926430916,0.33452611576463864,0.06384250748914849,0.06384250748914849,2.618889115071512 2937 Glycoside hydrolase superfamily [IPR017853] 9 15 3.364851576949488 0.0007658484439936 P10253,P16278,P54802,P06865,Q9BTY2,P04062,P07686,P04066,P06280 Sequence InterPro Superfamily interpro_homologous_superfamily 129,37,42,16,52,86,61,30,31 2006,86,30,31,16,61,144,129,37,1801,42,443,1265,52,999 -0.34089288926430916,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,2.1898966319486153,1.2712655154383892,1.3941514953495935,3.4162772870291325,-0.22216432068703482,3.078582353860239,0.6393489264185823,0.06384250748914849,2.618889115071512,0.228081190180689 2937 Cholesterol metabolism 8 22 3.3460287951488352 0.0008197788198633 Q14739,Q9UBM7,Q15392,O15118,P35610,Q15125,Q16850,P61916 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 35,38,71,75,53,26,27,62 75,1573,2457,86,521,2462,53,332,62,1375,1709,1932,1936,827,35,26,1833,71,2054,27,38,377 1.9547430671585866,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.5401492501085412,-0.6486147893595557,2.589890921013961,0.7836800160884329,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,3.4391717680711436,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,3.4162772870291325,0.7361572254974664 2937 Golgi apparatus 43 140 3.3460190186081795 0.000819807724778 Q9HB40,Q96SU4,P04439,Q969E2,Q8IXU6,Q92896,Q93050,Q9H2P9,Q92538,Q969M3,Q14376,Q6ZRP7,Q9Y4A5,P50897,O60637,Q5KU26,O75122,P49755,P16278,Q02818,Q14004,P11717,P80303,Q13190,P09601,P67812,Q9H8Y8,P50570,O60934,O15260,Q8N6T3,P24390,P98194,Q5VW38,O15258,P15289,Q8TBA6,Q14247,O15127,P07305,Q10471,Q9HD45,P50851 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 0,416,128,135,6,412,413,421,283,284,147,148,431,22,21,28,268,274,37,40,166,44,50,306,173,59,197,303,186,185,345,74,204,88,322,95,373,367,113,356,235,126,362 465,1559,514,1020,940,2102,2373,2579,113,322,185,1440,1659,1212,1333,2377,1116,2379,21,1335,186,268,1663,2523,1571,2300,572,640,796,128,356,173,2716,44,95,37,2530,2023,74,2929,2311,1689,2028,2684,1141,1045,1243,2885,1247,1591,274,303,362,22,1920,1146,532,2134,1924,2773,59,50,204,596,40,1263,2721,235,823,306,2050,166,367,147,982,1271,2656,28,2726,2337,88,2409,406,449,1274,2795,1387,148,2251,1845,1736,908,1955,1738,6,1080,912,345,2161,373,834,1392,2889,283,412,1293,413,135,284,1086,2730,1087,416,2610,1094,1095,2074,2760,421,1002,1983,2430,197,778,2434,1303,0,2781,126,2280,2085,927,1871,933,1768,784,1202,2442,431,432 0.5900489466309929,-0.10591263929674817,0.5401492501085412,0.17394576765407171,0.228081190180689,-0.4011890781327106,-0.5858198190406446,-0.7760889340064466,1.473918375909616,0.7836800160884329,1.101010637080487,-0.04871252906513763,-0.16372948749216756,0.06384250748914849,0.007872098580347686,-0.5858198190406446,0.11919997011538998,-0.5858198190406446,3.8063874677803375,0.007872098580347686,1.101010637080487,0.8770244243066478,-0.16372948749216756,-0.7120374352425395,-0.10591263929674817,-0.5236513396667263,0.48964847025575964,0.4385452506124256,0.33452611576463864,1.3941514953495935,0.7361572254974664,1.1442885584140452,-0.9720282133639213,2.94951498403428,1.7404982072045598,3.4162772870291325,-0.7120374352425395,-0.34089288926430916,1.9892736116862897,-6.1260774561706235,-0.5236513396667263,-0.16372948749216756,-0.34089288926430916,-0.906083163548422,0.11919997011538998,0.17394576765407171,0.06384250748914849,-1.8873708060077286,0.06384250748914849,-0.10591263929674817,0.8770244243066478,0.8306316454399105,0.7361572254974664,3.8063874677803375,-0.2812183777015856,0.11919997011538998,0.5401492501085412,-0.4011890781327106,-0.2812183777015856,-1.1058199287517425,2.222287625540094,2.618889115071512,1.057240248022844,0.48964847025575964,3.17849140779286,0.06384250748914849,-0.9720282133639213,0.9681807864168185,0.33452611576463864,0.8306316454399105,-0.34089288926430916,1.1870839548927827,0.7361572254974664,1.2712655154383892,0.228081190180689,0.06384250748914849,-0.8407704557687973,3.681306413452911,-0.9720282133639213,-0.5236513396667263,1.8491689704918812,-0.5858198190406446,0.688050566378247,0.6393489264185823,0.06384250748914849,-1.1736688722168886,0.007872098580347686,1.2712655154383892,-0.4621081592112762,-0.22216432068703482,-0.16372948749216756,0.2816075367943659,-0.2812183777015856,-0.16372948749216756,4.8486302687541105,0.17394576765407171,0.2816075367943659,0.7836800160884329,-0.4011890781327106,0.7361572254974664,0.33452611576463864,0.007872098580347686,-1.8873708060077286,0.8770244243066478,0.688050566378247,0.06384250748914849,0.688050566378247,1.3536292924938709,0.8770244243066478,0.17394576765407171,-0.9720282133639213,0.17394576765407171,0.688050566378247,-0.7760889340064466,0.17394576765407171,0.17394576765407171,-0.34089288926430916,-1.0386067543300004,0.688050566378247,0.228081190180689,-0.2812183777015856,-0.5858198190406446,1.101010637080487,0.38683824468201267,-0.5858198190406446,0.06384250748914849,5.893957451831641,-1.1058199287517425,1.434245143990909,-0.4621081592112762,-0.34089288926430916,0.2816075367943659,-0.22216432068703482,0.2816075367943659,-0.16372948749216756,0.38683824468201267,0.11919997011538998,-0.5858198190406446,0.688050566378247,0.688050566378247 2937 Hydrolase activity hydrolyzing o glycosyl compounds 8 19 3.330599549703956 0.0008665917080492 P16278,P54802,P06865,Q9BTY2,P04062,P07686,P04066,P06280 Functions GO Molecular function msigdb_gomf 37,42,16,52,86,61,30,31 2006,86,30,31,16,61,129,37,1801,42,443,826,1265,1271,2729,52,2183,1007,2093 -0.34089288926430916,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,2.1898966319486153,1.3941514953495935,3.4162772870291325,-0.22216432068703482,3.078582353860239,0.6393489264185823,0.33452611576463864,0.06384250748914849,0.06384250748914849,-0.9720282133639213,2.618889115071512,-0.4011890781327106,0.228081190180689,-0.34089288926430916 2937 Amide binding 24 96 3.32870730850129 0.0008725004408969 Q9UIQ6,P07602,P04439,Q8WTV0,Q14978,O14773,P42892,P11498,P40855,Q9H7Z7,P35610,O00763,P05165,O43813,Q15392,P24390,P04818,P09496,Q99735,Q9Y4U1,Q96AY3,Q9Y3C6,P01889,Q96RQ3 Functions GO Molecular function msigdb_gomf 2,3,128,14,278,24,25,390,164,181,53,292,298,66,71,74,325,326,243,248,105,247,120,415 637,1325,941,2519,567,292,24,859,2199,66,1023,2821,2382,1125,120,128,325,298,3,867,326,798,2923,390,1682,2461,394,2634,2531,74,1354,804,2126,1039,655,53,477,1470,164,1244,25,1365,1916,1367,2744,1696,1808,1478,2132,1921,1812,663,594,1483,2397,2877,818,886,1152,1376,536,2792,1491,2403,740,1497,1830,278,541,71,1393,14,763,1525,105,1747,415,844,2070,243,1635,773,1864,1002,181,2277,2705,2187,2188,1313,2707,2,1772,247,248,856 0.4385452506124256,0.007872098580347686,0.228081190180689,-0.7120374352425395,0.48964847025575964,0.8306316454399105,3.7652112572324823,0.2816075367943659,-0.4621081592112762,2.090959820673029,0.17394576765407171,-1.311278575581721,-0.5858198190406446,0.11919997011538998,1.434245143990909,1.3941514953495935,0.7836800160884329,0.8306316454399105,5.131894866624145,0.2816075367943659,0.7836800160884329,0.33452611576463864,-3.598238387349531,0.688050566378247,-0.16372948749216756,-0.6486147893595557,0.688050566378247,-0.8407704557687973,-0.7120374352425395,1.9892736116862897,0.007872098580347686,0.33452611576463864,-0.4011890781327106,0.17394576765407171,0.4385452506124256,2.589890921013961,0.5900489466309929,-0.04871252906513763,1.1870839548927827,0.06384250748914849,3.744431287238993,0.007872098580347686,-0.2812183777015856,0.007872098580347686,-1.0386067543300004,-0.16372948749216756,-0.22216432068703482,-0.04871252906513763,-0.4011890781327106,-0.2812183777015856,-0.22216432068703482,0.4385452506124256,0.48964847025575964,-0.04871252906513763,-0.5858198190406446,-1.739482229144661,0.33452611576463864,0.2816075367943659,0.11919997011538998,0.007872098580347686,0.5401492501085412,-1.1736688722168886,-0.04871252906513763,-0.5858198190406446,0.38683824468201267,-0.04871252906513763,-0.22216432068703482,0.8770244243066478,0.5401492501085412,2.057376685439682,0.007872098580347686,4.192232038011874,0.38683824468201267,-0.04871252906513763,1.628562285011634,-0.16372948749216756,0.688050566378247,0.33452611576463864,-0.34089288926430916,0.9681807864168185,-0.10591263929674817,0.38683824468201267,-0.22216432068703482,0.228081190180689,1.1442885584140452,-0.4621081592112762,-0.906083163548422,-0.4011890781327106,-0.4011890781327106,0.06384250748914849,-0.906083163548422,5.198840694526526,-0.16372948749216756,0.9681807864168185,0.9681807864168185,0.33452611576463864 2937 Endocytic vesicle 24 72 3.306074224940295 0.0009461302103932 Q15286,P04439,Q93050,Q14108,Q8WTV0,Q9Y487,P61006,O15400,Q5KU26,P20645,P13473,P02786,P11233,P11717,Q9H4M9,P11279,P51790,O60493,P50570,Q15942,P09496,Q9Y5K6,Q14254,P01889 Localization GO Cellular component msigdb_gocc 256,128,413,8,14,430,395,383,28,152,36,41,162,44,318,48,49,293,303,84,326,382,368,120 1114,2578,2768,383,293,1663,1219,2114,1670,120,41,128,713,2018,326,798,2923,162,48,44,36,1229,716,152,804,1909,1140,1240,588,303,1480,1143,1051,1919,49,1052,2899,1599,395,1373,972,1149,818,1062,1497,1719,1498,2653,8,368,1267,256,1725,984,84,542,28,405,1843,14,2261,413,2664,1747,1638,318,1316,935,430,2919,511,382 0.11919997011538998,-0.7760889340064466,-1.1058199287517425,0.688050566378247,0.8306316454399105,-0.16372948749216756,0.06384250748914849,-0.4011890781327106,-0.16372948749216756,1.434245143990909,3.1288971739076072,1.3941514953495935,0.38683824468201267,-0.34089288926430916,0.7836800160884329,0.33452611576463864,-3.598238387349531,1.1870839548927827,2.618889115071512,2.94951498403428,3.4162772870291325,0.06384250748914849,0.38683824468201267,1.229406481355582,0.33452611576463864,-0.2812183777015856,0.11919997011538998,0.06384250748914849,0.48964847025575964,0.8306316454399105,-0.04871252906513763,0.11919997011538998,0.17394576765407171,-0.2812183777015856,2.618889115071512,0.17394576765407171,-2.0378507439803,-0.10591263929674817,0.688050566378247,0.007872098580347686,0.228081190180689,0.11919997011538998,0.33452611576463864,0.17394576765407171,-0.04871252906513763,-0.16372948749216756,-0.04871252906513763,-0.8407704557687973,4.712282471751374,0.7361572254974664,0.06384250748914849,0.9228702829555585,-0.16372948749216756,0.228081190180689,1.8846964555914798,0.5401492501085412,3.681306413452911,0.688050566378247,-0.22216432068703482,4.192232038011874,-0.4621081592112762,0.688050566378247,-0.8407704557687973,-0.16372948749216756,-0.10591263929674817,0.8306316454399105,0.06384250748914849,0.2816075367943659,0.688050566378247,-2.9956170913795845,0.5900489466309929,0.7361572254974664 2937 Protease 13 111 3.305071221169994 0.0009495226798066 Q9HB40,Q9H3G5,Q9UIQ6,P42785,P02786,Q5BJF2,O75844,Q92820,Q13510,O14773,P42892,P10619,P67812 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 0,1,2,5,41,11,19,54,55,24,25,58,59 1562,2296,466,2625,24,468,790,1444,2627,19,387,2524,2013,41,1128,643,58,2529,187,582,1682,1901,1133,2462,1233,1236,1796,1136,2029,527,2885,2927,5,25,2129,2130,2475,813,2912,2395,1812,203,1053,1250,663,729,1600,2229,59,889,2046,538,1935,55,2237,2327,403,1381,2052,2330,2055,1167,280,11,157,2248,2338,2751,2843,1623,98,2415,1514,911,1285,2556,680,2889,761,54,553,2422,2347,2500,1396,2168,1855,839,496,1530,2609,2733,687,773,1,847,0,2358,2614,627,2187,1196,1198,2670,2,2444,380,2515,1016,1652,2516 -0.10591263929674817,-0.5236513396667263,0.5900489466309929,-0.8407704557687973,3.7652112572324823,0.5900489466309929,0.33452611576463864,-0.04871252906513763,-0.8407704557687973,3.926946339483657,0.688050566378247,-0.7120374352425395,-0.34089288926430916,3.1288971739076072,0.11919997011538998,0.4385452506124256,2.3177619175977977,-0.7120374352425395,1.101010637080487,0.48964847025575964,-0.16372948749216756,-0.2812183777015856,0.11919997011538998,-0.6486147893595557,0.06384250748914849,0.06384250748914849,-0.22216432068703482,0.11919997011538998,-0.34089288926430916,0.5401492501085412,-1.8873708060077286,-4.421251316217688,4.863421508907323,3.744431287238993,-0.4011890781327106,-0.4011890781327106,-0.6486147893595557,0.33452611576463864,-2.425443155290095,-0.5858198190406446,-0.22216432068703482,1.057240248022844,0.17394576765407171,0.06384250748914849,0.4385452506124256,0.38683824468201267,-0.10591263929674817,-0.4621081592112762,2.222287625540094,0.2816075367943659,-0.34089288926430916,0.5401492501085412,-0.2812183777015856,2.5014551385438826,-0.4621081592112762,-0.5236513396667263,0.688050566378247,0.007872098580347686,-0.34089288926430916,-0.5236513396667263,-0.34089288926430916,0.11919997011538998,0.8770244243066478,4.2819961355673675,1.229406481355582,-0.4621081592112762,-0.5236513396667263,-1.0386067543300004,-1.451444818165324,-0.10591263929674817,1.7035577277228184,-0.5858198190406446,-0.04871252906513763,0.2816075367943659,0.06384250748914849,-0.7120374352425395,0.4385452506124256,-1.8873708060077286,0.38683824468201267,2.5311775269119203,0.5401492501085412,-0.5858198190406446,-0.5236513396667263,-0.6486147893595557,0.007872098580347686,-0.4011890781327106,-0.22216432068703482,0.33452611576463864,0.5900489466309929,-0.04871252906513763,-0.7760889340064466,-0.9720282133639213,0.4385452506124256,0.38683824468201267,5.830215713580066,0.33452611576463864,5.893957451831641,-0.5236513396667263,-0.7760889340064466,0.48964847025575964,-0.4011890781327106,0.11919997011538998,0.11919997011538998,-0.8407704557687973,5.198840694526526,-0.5858198190406446,0.7361572254974664,-0.6486147893595557,0.228081190180689,-0.10591263929674817,-0.6486147893595557 2937 Cognitive impairment 40 157 3.3043495282534656 0.0009519706354803 P07602,O75503,P20700,Q99720,Q14108,P06865,Q9Y487,Q9BQE5,P50897,Q8WVX9,O75165,P06280,P12235,P13473,P16278,P40855,P54802,Q4G176,Q13510,P56589,O96008,Q9UEY8,P07686,P61916,O60934,P11166,Q04446,O15118,Q13426,Q96QK1,Q6DKK2,P04062,P15289,Q99496,Q9Y4U1,Q9NQZ5,P35637,O96011,Q9Y619,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,4,133,7,8,16,430,23,22,410,269,31,391,36,37,164,42,404,55,174,297,461,61,62,186,437,443,75,337,498,492,86,95,96,248,246,359,355,127,120 1326,75,1443,706,1661,186,269,1446,1024,4,2787,2832,1668,1343,575,297,355,2458,1790,120,86,1576,1347,2206,31,16,3,61,1675,2118,2527,2305,714,437,391,36,1900,95,37,1035,1684,1794,133,1905,523,1688,802,1232,1462,1235,2534,1690,1043,359,967,2127,164,588,1245,875,1589,968,2032,1367,1695,1477,22,1920,1249,2037,1146,971,42,1815,2478,174,1702,1598,2479,1483,62,1057,1062,596,443,736,2649,1490,538,1716,2546,2690,337,55,8,1065,1161,1829,1612,2051,2056,404,2335,2245,987,492,1949,750,2410,1276,2251,2921,678,913,2159,915,410,1746,763,1853,2607,498,997,2270,96,2609,2173,2501,7,23,2901,1757,1004,246,1102,1195,1417,2187,2866,2188,1010,2189,461,2845,2512,1767,1873,632,2093,509,1650,2622,430,248,1016,1556,127 0.007872098580347686,1.9547430671585866,-0.04871252906513763,0.38683824468201267,-0.16372948749216756,1.101010637080487,0.8770244243066478,-0.04871252906513763,0.17394576765407171,4.878143286316388,-1.1736688722168886,-1.3810415738737563,-0.16372948749216756,0.007872098580347686,0.48964847025575964,0.8306316454399105,0.7361572254974664,-0.6486147893595557,-0.22216432068703482,1.434245143990909,1.8491689704918812,-0.10591263929674817,0.007872098580347686,-0.4621081592112762,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,-0.16372948749216756,-0.4011890781327106,-0.7120374352425395,-0.5236513396667263,0.38683824468201267,0.6393489264185823,0.688050566378247,3.4162772870291325,-0.2812183777015856,1.7404982072045598,3.4162772870291325,0.17394576765407171,-0.16372948749216756,-0.22216432068703482,1.3536292924938709,-0.2812183777015856,0.5401492501085412,-0.16372948749216756,0.33452611576463864,0.06384250748914849,-0.04871252906513763,0.06384250748914849,-0.7120374352425395,-0.16372948749216756,0.17394576765407171,0.7361572254974664,0.228081190180689,-0.4011890781327106,1.1870839548927827,0.48964847025575964,0.06384250748914849,0.2816075367943659,-0.10591263929674817,0.228081190180689,-0.34089288926430916,0.007872098580347686,-0.16372948749216756,-0.04871252906513763,3.8063874677803375,-0.2812183777015856,0.06384250748914849,-0.34089288926430916,0.11919997011538998,0.228081190180689,3.078582353860239,-0.22216432068703482,-0.6486147893595557,1.1442885584140452,-0.16372948749216756,-0.10591263929674817,-0.6486147893595557,-0.04871252906513763,2.157214859958303,0.17394576765407171,0.17394576765407171,0.48964847025575964,0.6393489264185823,0.38683824468201267,-0.8407704557687973,-0.04871252906513763,0.5401492501085412,-0.16372948749216756,-0.7120374352425395,-0.906083163548422,0.7836800160884329,2.5014551385438826,4.712282471751374,0.17394576765407171,0.11919997011538998,-0.22216432068703482,-0.10591263929674817,-0.34089288926430916,-0.34089288926430916,0.688050566378247,-0.5236513396667263,-0.4621081592112762,0.228081190180689,0.5900489466309929,-0.2812183777015856,0.38683824468201267,-0.5858198190406446,0.06384250748914849,-0.4621081592112762,-3.510150275167924,0.4385452506124256,0.2816075367943659,-0.4011890781327106,0.2816075367943659,0.688050566378247,-0.16372948749216756,0.38683824468201267,-0.22216432068703482,-0.7760889340064466,0.5900489466309929,0.228081190180689,-0.4621081592112762,1.7404982072045598,-0.7760889340064466,-0.4011890781327106,-0.6486147893595557,4.758390219688548,3.8063874677803375,-2.0378507439803,-0.16372948749216756,0.228081190180689,0.9681807864168185,0.17394576765407171,0.11919997011538998,0.007872098580347686,-0.4011890781327106,-1.5941764518204824,-0.4011890781327106,0.228081190180689,-0.4011890781327106,0.6393489264185823,-1.451444818165324,-0.6486147893595557,-0.16372948749216756,-0.22216432068703482,0.48964847025575964,-0.34089288926430916,0.5900489466309929,-0.10591263929674817,-0.7760889340064466,0.688050566378247,0.9681807864168185,0.228081190180689,-0.04871252906513763,1.434245143990909 2937 Serine hydrolase activity 9 18 3.302010707187664 0.0009599440571919 Q9HB40,Q9H3G5,O75976,P42785,Q4J6C6,O14773,Q5JRX3,P10619,P67812 Functions GO Molecular function msigdb_gomf 0,1,34,5,85,24,157,58,59 24,34,58,582,1136,527,5,2130,1812,203,59,672,85,157,904,2415,1,0 3.7652112572324823,3.4391717680711436,2.3177619175977977,0.48964847025575964,0.11919997011538998,0.5401492501085412,4.863421508907323,-0.4011890781327106,-0.22216432068703482,1.057240248022844,2.222287625540094,0.4385452506124256,1.8846964555914798,1.229406481355582,0.2816075367943659,-0.5858198190406446,5.830215713580066,5.893957451831641 2937 Transporters 98 320 3.2997840167480024 0.0009675926420811 P07602,Q8IXU6,Q99720,Q14108,Q5BJF2,O43772,P08183,Q8WTV0,O75844,O60637,P13473,P02786,P11717,P11279,Q9NR77,P61916,Q9Y6M7,O95342,P24390,O15118,Q9H061,Q5VW38,Q99808,O14786,O15127,P51798,Q96GC9,P51572,Q9Y619,Q8N511,P04439,Q969E2,P55011,Q9BTX1,Q9BUN8,P35613,Q12834,P08195,O60826,Q15629,P20645,Q9UM00,P40855,Q9ULH0,P56589,P78310,O15260,Q6ZXV5,Q99805,Q8WY22,P98194,Q6NUK1,O75915,O43592,Q96N66,Q9NQZ5,Q5J8M3,Q9HD20,O94979,O14828,Q07157,Q969V3,O14975,O15397,P49257,P49755,P53985,Q15758,Q9H2D1,Q13190,O60493,O96008,P50570,Q16799,Q15363,O96005,P09496,O15258,Q8IUX1,Q9Y320,Q9Y5K6,Q8TBA6,Q96A57,Q93050,Q92890,Q8TEM1,Q8N1F7,P12235,Q07065,Q96A65,O75027,P11166,P13073,Q07021,Q96QK1,Q9H3N1,Q9Y4L1,Q9Y639 Functions Protein Atlas Protein class protein_atlas_protein_class 3,6,7,8,11,12,13,14,19,21,36,41,44,48,57,62,72,69,74,75,81,88,99,97,113,115,118,122,127,131,128,135,138,140,149,145,146,144,143,156,152,172,164,183,174,188,185,205,207,206,204,220,213,211,242,246,239,262,250,249,255,285,266,267,272,274,276,310,317,306,293,297,303,340,339,324,326,322,371,379,382,373,414,413,411,409,408,391,401,455,434,437,438,444,498,503,511,512 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2937 CD markers 7 11 3.290210427594729 0.0010011248497205 O14786,P13473,P02786,P11717,P08183,P11279,P35613 Functions Protein Atlas Protein class protein_atlas_protein_class 97,36,41,44,13,48,145 97,41,797,13,144,48,44,36,145,1369,1378 1.7035577277228184,3.1288971739076072,0.33452611576463864,4.192232038011874,1.2712655154383892,2.618889115071512,2.94951498403428,3.4162772870291325,1.2712655154383892,0.007872098580347686,0.007872098580347686 2937 Abnormal circulating cholesterol concentration 11 30 3.2886682963619123 0.0010066258207006 O75845,Q8N511,P50402,P07602,Q14739,Q9UBM7,Q15392,P38571,Q10471,Q15125,P61916 Drugs and Diseases Human Phenotype Ontology msigdb_hp 212,131,217,3,35,38,71,17,235,26,62 2009,212,1894,712,3,332,17,875,2222,217,1920,1598,62,235,445,980,35,26,71,2054,2844,131,1519,1178,258,2360,2188,38,1767,2623 -0.34089288926430916,1.0129671489863166,-0.2812183777015856,0.38683824468201267,5.131894866624145,0.7836800160884329,3.9856208887046614,0.2816075367943659,-0.4621081592112762,1.0129671489863166,-0.2812183777015856,-0.10591263929674817,2.157214859958303,0.9681807864168185,0.6393489264185823,0.228081190180689,3.4391717680711436,3.7024803541208557,2.057376685439682,-0.34089288926430916,-1.451444818165324,1.3941514953495935,-0.04871252906513763,0.11919997011538998,0.9228702829555585,-0.5236513396667263,-0.4011890781327106,3.4162772870291325,-0.16372948749216756,-0.7760889340064466 2937 Abnormality of the tongue 17 84 3.228480330938689 0.0012444981675423 Q99496,P10253,Q6NUK1,P16278,Q9UBM7,Q01433,P20700,P40855,O15460,O75844,O60826,Q9H4A3,Q13510,P56589,P01889,P07686,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,129,220,37,38,103,133,164,200,19,143,160,55,174,120,61,30 939,1563,1434,1021,467,200,143,2009,1783,19,1573,1787,575,355,120,1894,30,1347,61,2526,129,37,133,961,1905,1688,1232,872,2684,164,529,2771,1590,2536,2034,1367,592,726,2478,174,2229,595,1150,2138,596,103,1262,538,540,55,598,1501,2775,1503,2693,1510,220,2699,344,1294,1852,2067,96,1091,1974,1859,2569,1191,2428,160,1539,1540,1194,2085,929,1007,38,2287,2802,1999,248,1556,2711,513 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2937 Ion transmembrane transporter activity 28 86 3.22836457002756 0.0012450019452554 Q93050,P55011,O43772,Q9Y487,P08195,P06576,Q9UM00,P53985,P12235,Q15758,P21796,Q9H2D1,P51790,P24539,Q14728,O75947,Q14847,P11166,Q9Y6M7,O75964,P98194,Q6NUK1,P56385,Q99808,P51798,Q13423,Q9Y619,Q9HD20 Functions GO Molecular function msigdb_gomf 413,138,12,430,144,389,172,276,391,310,394,317,49,299,177,296,447,437,72,77,204,220,334,99,115,117,127,262 2100,1437,1443,12,862,1570,296,77,1452,574,2458,1895,1223,389,2304,1896,144,1581,2119,579,437,391,1458,438,1900,957,1686,1687,961,869,394,299,2215,807,2029,1692,967,2127,1365,724,2743,49,115,1922,276,138,2038,334,1149,1483,204,1604,2480,1261,117,177,447,310,2334,2727,220,2339,608,752,2498,549,614,1293,413,2561,685,99,1974,317,923,693,262,1200,1422,2782,1767,172,2292,430,127,72 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2937 Abnormality of bone mineral density 19 128 3.225087881479299 0.0012593400461502 P07602,Q14108,O75844,Q9H4A3,Q15125,P06280,Q14739,P16278,P54802,Q13510,Q96L58,P52788,Q15392,P12955,Q32P28,Q9H490,P04062,Q96AY3,P51798 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,8,19,160,26,31,35,37,42,55,196,70,71,187,80,91,86,105,115 939,1778,1437,942,467,1438,1332,1441,789,1118,707,2009,2112,1569,2299,19,212,1452,1892,1027,575,2015,1790,1894,86,298,2208,1673,31,712,1127,1674,3,714,391,187,2868,37,2213,1132,1684,1794,1905,523,1586,1463,1907,1038,1468,1360,2684,2314,1363,2471,2885,1473,2034,970,2037,115,1052,70,2899,971,42,1815,2478,1254,1598,594,2229,1707,1150,1823,2594,1931,484,1607,1494,1156,540,55,8,981,35,1612,2775,1503,26,1163,71,745,1165,80,986,2337,1731,1735,1280,551,1746,1181,453,105,346,196,997,260,1982,1538,91,160,1540,693,2509,2182,851,1766,2186,2188,2287,1996,2896,2709,430,2802,2905,2295 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2937 Vacuole organization 10 42 3.210742631381807 0.0013239244995715 Q8N511,O75503,Q14108,P11117,P54802,P50897,Q96GC9,O14773,P04062,P07686 Processes and pathways GO Biological process msigdb_gobp 131,4,8,9,42,22,118,24,86,61 1020,24,1219,4,1668,2383,1028,86,2304,61,129,9,957,716,588,362,22,1051,42,2543,972,1059,8,2775,256,1271,406,131,1288,118,2890,498,1638,502,2428,2086,852,2922,1201,2368,634,2515 0.17394576765407171,3.7652112572324823,0.06384250748914849,4.878143286316388,-0.16372948749216756,-0.5858198190406446,0.17394576765407171,1.8491689704918812,-0.5236513396667263,2.1898966319486153,1.3941514953495935,4.437559793002022,0.228081190180689,0.38683824468201267,0.48964847025575964,0.7361572254974664,3.8063874677803375,0.17394576765407171,3.078582353860239,-0.7120374352425395,0.228081190180689,0.17394576765407171,4.712282471751374,-1.1058199287517425,0.9228702829555585,0.06384250748914849,0.688050566378247,1.3941514953495935,0.06384250748914849,1.473918375909616,-1.8873708060077286,0.5900489466309929,-0.10591263929674817,0.5900489466309929,-0.5858198190406446,-0.34089288926430916,0.33452611576463864,-3.510150275167924,0.11919997011538998,-0.5236513396667263,0.48964847025575964,-0.6486147893595557 2937 Organic hydroxy compound metabolic process 23 102 3.182974512110172 0.0014577044544563 Q8WTV0,P38571,Q9BQE5,Q15125,O14975,Q16850,P17174,P51648,Q14739,Q9UBM7,P35610,Q13510,P61916,Q15392,O95342,O15118,P04062,P48735,P37268,O75845,Q9UHB6,O60762,P09110 Processes and pathways GO Biological process msigdb_gobp 14,17,23,26,266,27,151,275,35,38,53,55,62,71,69,75,86,216,332,212,377,228,357 1206,266,75,1022,2198,1333,386,228,1570,212,948,1573,69,2014,1671,1125,2457,2205,86,2206,2525,1791,357,799,2210,521,2120,1230,1352,2213,151,802,2023,2634,2462,653,2388,2834,1043,53,332,2869,17,2472,1474,2391,216,2744,2591,878,1920,1249,275,1701,2542,2396,2822,62,2401,1375,1709,1932,538,1936,55,2750,827,2146,35,1382,1502,26,1833,71,1067,2054,2333,27,746,1511,1516,2255,2257,14,2819,2562,498,416,2609,2501,2502,23,2081,1542,1544,1418,38,377,2763,2098,2919,2295 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2937 Sterol metabolism 8 24 3.172360569461863 0.001512051465135 Q14739,Q9UBM7,Q15392,O15118,P35610,Q15125,Q16850,P61916 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 35,38,71,75,53,26,27,62 75,212,1573,2457,86,521,2462,53,332,62,1375,1709,1932,1936,827,35,26,1833,71,2054,27,38,377,2763 1.9547430671585866,1.0129671489863166,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.5401492501085412,-0.6486147893595557,2.589890921013961,0.7836800160884329,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,3.4391717680711436,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,3.4162772870291325,0.7361572254974664,-1.0386067543300004 2937 Lytic vacuole organization 9 20 3.169097383115392 0.0015291315122629 Q8N511,O75503,Q14108,P11117,P54802,P50897,O14773,P04062,P07686 Processes and pathways GO Biological process msigdb_gobp 131,4,8,9,42,22,24,86,61 1020,24,4,86,61,129,9,588,22,1051,42,972,8,406,131,498,1638,852,2922,1201 0.17394576765407171,3.7652112572324823,4.878143286316388,1.8491689704918812,2.1898966319486153,1.3941514953495935,4.437559793002022,0.48964847025575964,3.8063874677803375,0.17394576765407171,3.078582353860239,0.228081190180689,4.712282471751374,0.688050566378247,1.3941514953495935,0.5900489466309929,-0.10591263929674817,0.33452611576463864,-3.510150275167924,0.11919997011538998 2937 Abnormality of the biliary system 18 113 3.164452612609619 0.0015537496151714 O75845,P07602,Q14739,P12955,Q9UBM7,Q14108,O95342,P40855,O15118,Q14376,P38571,P09601,Q13510,P61916,P56589,P04062,P04066,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 212,3,35,187,38,8,69,164,75,147,17,173,55,62,174,86,30,95 1559,1205,1329,75,1443,1783,1890,212,1452,69,355,2015,1125,1894,86,30,1672,2206,712,578,3,2017,2117,173,714,437,1033,799,187,2212,800,95,646,2681,2461,802,2463,653,2684,2741,1361,527,1362,2849,2314,17,164,1244,529,1803,724,1248,2744,1920,1249,2037,1368,1147,971,1053,2540,1148,2643,174,2396,2745,62,1150,2139,596,484,823,538,1156,2691,55,8,147,35,1503,1505,1386,987,2551,449,750,2699,2796,1742,1289,2700,1746,411,1181,1294,1968,2172,1760,1982,1538,2509,2188,38,2287,1767,1314,2368,2093,2094,1319,2802,248,2905 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2937 Hydrops fetalis 18 40 3.159921449449004 0.0015781167889699 P46777,Q14739,P61353,P18077,P61313,P42766,P16278,P62847,Q9BT22,Q04446,Q9Y4U1,P61254,Q13510,P62244,P10619,P04062,P39019,Q07020 Drugs and Diseases Human Phenotype Ontology msigdb_hp 440,35,252,522,396,137,37,139,316,443,248,481,55,482,58,86,333,537 1663,1340,1789,86,1673,1792,58,1033,37,522,2309,657,333,1244,137,1247,440,969,1367,2540,2479,481,396,252,533,482,1705,139,2809,731,1707,443,537,55,35,1742,1852,316,1763,248 -0.16372948749216756,0.007872098580347686,-0.22216432068703482,1.8491689704918812,-0.16372948749216756,-0.22216432068703482,2.3177619175977977,0.17394576765407171,3.4162772870291325,0.5401492501085412,-0.5236513396667263,0.4385452506124256,0.7836800160884329,0.06384250748914849,1.3126701679029467,0.06384250748914849,0.6393489264185823,0.228081190180689,0.007872098580347686,-0.7120374352425395,-0.6486147893595557,0.5900489466309929,0.688050566378247,0.9228702829555585,0.5401492501085412,0.5900489466309929,-0.16372948749216756,1.3126701679029467,-1.2421547136861633,0.38683824468201267,-0.16372948749216756,0.6393489264185823,0.5401492501085412,2.5014551385438826,3.4391717680711436,-0.16372948749216756,-0.22216432068703482,0.8306316454399105,-0.16372948749216756,0.9681807864168185 2937 Steroid metabolism 8 25 3.1487300411665715 0.0016398160246924 Q14739,Q9UBM7,Q15392,O15118,P35610,Q15125,Q16850,P61916 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 35,38,71,75,53,26,27,62 75,212,1573,2457,86,521,2462,53,332,62,1375,1709,1932,1936,827,35,26,1833,71,2054,27,2501,38,377,2763 1.9547430671585866,1.0129671489863166,-0.10591263929674817,-0.6486147893595557,1.8491689704918812,0.5401492501085412,-0.6486147893595557,2.589890921013961,0.7836800160884329,2.157214859958303,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,3.4391717680711436,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,3.7024803541208557,-0.6486147893595557,3.4162772870291325,0.7361572254974664,-1.0386067543300004 2937 Pigment granule 10 55 3.1428600772458237 0.0016730579506198 P49755,Q15286,P02786,O43852,P11279,P35613,P08195,Q92820,O14773,Q92542 Localization GO Cellular component msigdb_gocc 274,256,41,47,48,145,144,54,24,158 24,47,1219,1571,41,519,1895,797,1674,2304,713,1896,144,867,645,1457,437,48,868,1229,716,961,2531,2309,805,1465,1909,656,145,1367,274,1594,1480,1143,1051,1369,727,2227,1704,1059,1374,1487,1062,895,1265,1613,256,310,2155,1522,158,54,413,1858,938 3.7652112572324823,2.760432113941949,0.06384250748914849,-0.10591263929674817,3.1288971739076072,0.5401492501085412,-0.2812183777015856,0.33452611576463864,-0.16372948749216756,-0.5236513396667263,0.38683824468201267,-0.2812183777015856,1.2712655154383892,0.2816075367943659,0.4385452506124256,-0.04871252906513763,0.6393489264185823,2.618889115071512,0.2816075367943659,0.06384250748914849,0.38683824468201267,0.228081190180689,-0.7120374352425395,-0.5236513396667263,0.33452611576463864,-0.04871252906513763,-0.2812183777015856,0.4385452506124256,1.2712655154383892,0.007872098580347686,0.8770244243066478,-0.10591263929674817,-0.04871252906513763,0.11919997011538998,0.17394576765407171,0.007872098580347686,0.38683824468201267,-0.4621081592112762,-0.16372948749216756,0.17394576765407171,0.007872098580347686,-0.04871252906513763,0.17394576765407171,0.2816075367943659,0.06384250748914849,-0.10591263929674817,0.9228702829555585,0.8306316454399105,-0.4011890781327106,-0.04871252906513763,1.229406481355582,2.5311775269119203,0.688050566378247,-0.22216432068703482,0.2816075367943659 2937 Abnormal rib cage morphology 17 66 3.133453148100517 0.0017276249693407 Q9UM00,Q14739,Q96HY6,P16278,Q9UBM7,Q9UBN7,P54802,Q32P28,P41227,O75844,P15586,O60826,P51798,Q9Y619,Q96L58,P04066,P50570 Drugs and Diseases Human Phenotype Ontology msigdb_hp 172,35,346,37,38,210,42,80,231,19,20,143,115,127,196,30,303 942,143,1663,2009,1569,2299,19,1452,575,2015,1790,1894,30,1674,20,37,1352,1132,646,961,1905,1232,1586,2531,2929,872,333,231,2034,970,303,115,42,594,2594,1931,2140,1156,2691,35,1269,2054,1165,2406,80,1510,2811,2058,2251,1735,1742,1180,1852,346,196,1970,1091,1403,1982,38,210,1108,172,2709,1878,127 0.228081190180689,1.2712655154383892,-0.16372948749216756,-0.34089288926430916,-0.10591263929674817,-0.5236513396667263,3.926946339483657,-0.04871252906513763,0.48964847025575964,-0.34089288926430916,-0.22216432068703482,-0.2812183777015856,3.6169723053440874,-0.16372948749216756,3.887244197186541,3.4162772870291325,0.007872098580347686,0.11919997011538998,0.4385452506124256,0.228081190180689,-0.2812183777015856,0.06384250748914849,-0.10591263929674817,-0.7120374352425395,-6.1260774561706235,0.2816075367943659,0.7836800160884329,0.9681807864168185,-0.34089288926430916,0.228081190180689,0.8306316454399105,1.473918375909616,3.078582353860239,0.48964847025575964,-0.7760889340064466,-0.2812183777015856,-0.4011890781327106,0.11919997011538998,-0.906083163548422,3.4391717680711436,0.06384250748914849,-0.34089288926430916,0.11919997011538998,-0.5858198190406446,1.919885894471246,-0.04871252906513763,-1.2421547136861633,-0.34089288926430916,-0.4621081592112762,-0.16372948749216756,-0.16372948749216756,0.11919997011538998,-0.22216432068703482,0.7836800160884329,1.101010637080487,-0.2812183777015856,0.17394576765407171,0.007872098580347686,-0.2812183777015856,3.4162772870291325,1.057240248022844,0.17394576765407171,1.1870839548927827,-0.906083163548422,-0.22216432068703482,1.434245143990909 2937 Myoclonic seizure 11 50 3.126815549478876 0.001767107558761 P07602,O75503,P16278,P52788,Q96N66,Q9Y3C6,Q13510,Q9Y619,P04062,P07686,Q01105 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,4,37,70,242,247,55,127,86,61,123 1326,1115,1441,789,2107,1566,1886,228,4,1666,86,3,61,437,37,1688,2534,2471,810,2886,1249,2808,70,595,1062,123,2649,55,669,1829,2337,987,2698,1955,1513,453,2268,1747,1749,1968,242,846,1763,2188,1548,2290,247,1431,1016,127 0.007872098580347686,0.11919997011538998,-0.04871252906513763,0.33452611576463864,-0.4011890781327106,-0.10591263929674817,-0.2812183777015856,0.9681807864168185,4.878143286316388,-0.16372948749216756,1.8491689704918812,5.131894866624145,2.1898966319486153,0.6393489264185823,3.4162772870291325,-0.16372948749216756,-0.7120374352425395,-0.6486147893595557,0.33452611576463864,-1.8873708060077286,0.06384250748914849,-1.2421547136861633,2.057376685439682,0.48964847025575964,0.17394576765407171,1.434245143990909,-0.8407704557687973,2.5014551385438826,0.4385452506124256,-0.22216432068703482,-0.5236513396667263,0.228081190180689,-0.906083163548422,-0.2812183777015856,-0.04871252906513763,0.6393489264185823,-0.4621081592112762,-0.16372948749216756,-0.16372948749216756,-0.2812183777015856,0.9681807864168185,0.33452611576463864,-0.16372948749216756,-0.4011890781327106,-0.04871252906513763,-0.4621081592112762,0.9681807864168185,0.007872098580347686,0.228081190180689,1.434245143990909 2937 Anatomical structure homeostasis 8 33 3.126478075773768 0.0017691369505565 P10253,P13473,P78310,P55011,P02786,P38571,P51790,O14773 Processes and pathways GO Biological process msigdb_gobp 129,36,188,138,41,17,49,24 24,1028,41,1672,797,2017,2117,129,437,36,393,1686,523,1360,17,1588,1051,49,138,188,2480,2140,255,1715,485,1936,1065,1836,1276,2256,1548,1773,2099 3.7652112572324823,0.17394576765407171,3.1288971739076072,-0.16372948749216756,0.33452611576463864,-0.34089288926430916,-0.4011890781327106,1.3941514953495935,0.6393489264185823,3.4162772870291325,0.688050566378247,-0.16372948749216756,0.5401492501085412,0.007872098580347686,3.9856208887046614,-0.10591263929674817,0.17394576765407171,2.618889115071512,1.3126701679029467,1.101010637080487,-0.6486147893595557,-0.4011890781327106,0.9228702829555585,-0.16372948749216756,0.5900489466309929,-0.2812183777015856,0.17394576765407171,-0.22216432068703482,0.06384250748914849,-0.4621081592112762,-0.04871252906513763,-0.16372948749216756,-0.34089288926430916 2937 Locomotory behavior 6 28 3.1263459257208543 0.0017699322160198 P54802,O15118,P51790,O75844,P50897,P07686 Processes and pathways GO Biological process msigdb_gobp 42,75,49,19,22,61 2196,75,2004,1337,19,2205,1576,1346,61,645,129,1140,588,810,1591,22,1249,49,42,2401,307,896,1725,1276,911,498,2609,1641 -0.4621081592112762,1.9547430671585866,-0.34089288926430916,0.007872098580347686,3.926946339483657,-0.4621081592112762,-0.10591263929674817,0.007872098580347686,2.1898966319486153,0.4385452506124256,1.3941514953495935,0.11919997011538998,0.48964847025575964,0.33452611576463864,-0.10591263929674817,3.8063874677803375,0.06384250748914849,2.618889115071512,3.078582353860239,-0.5858198190406446,0.8306316454399105,0.2816075367943659,-0.16372948749216756,0.06384250748914849,0.2816075367943659,0.5900489466309929,-0.7760889340064466,-0.10591263929674817 2937 Abnormal conjunctiva morphology 6 26 3.124725480312956 0.0017797106488113 Q14739,P02786,Q13510,P10619,P04066,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,41,55,58,30,31 707,120,41,30,1673,31,58,2211,1684,1794,1688,1463,586,1356,2683,1367,1478,362,823,2691,55,35,2159,1746,2182,2187 0.38683824468201267,1.434245143990909,3.1288971739076072,3.6169723053440874,-0.16372948749216756,3.6169723053440874,2.3177619175977977,-0.4621081592112762,-0.16372948749216756,-0.22216432068703482,-0.16372948749216756,-0.04871252906513763,0.48964847025575964,0.007872098580347686,-0.906083163548422,0.007872098580347686,-0.04871252906513763,0.7361572254974664,0.33452611576463864,-0.906083163548422,2.5014551385438826,3.4391717680711436,-0.4011890781327106,-0.16372948749216756,-0.4011890781327106,-0.4011890781327106 2937 Abnormality of temperature regulation 15 101 3.117666546532817 0.0018228891976102 P07602,Q14739,P10253,P20700,Q9Y4U1,O43772,O15460,P38571,P51798,P35610,Q13510,P51572,Q9NR77,P01889,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,35,129,133,248,12,200,17,115,53,55,122,57,120,31 942,1329,200,705,12,1445,1890,1787,1027,796,1671,2458,120,1672,2206,31,1127,3,2118,129,714,1033,799,800,1684,1794,133,1232,718,2466,804,586,1043,53,2741,2898,1142,1362,17,2471,2473,724,1367,2744,1477,1808,725,303,122,115,232,1813,1054,2643,1598,594,2229,596,2594,1932,2141,1716,739,55,1718,1161,1829,35,1723,1267,603,1729,2599,2245,987,2058,2753,408,1515,548,2159,2499,915,916,1746,374,2827,1191,1639,693,2082,1102,57,2187,2188,1009,2845,2512,1319,248,382 0.228081190180689,0.007872098580347686,1.057240248022844,0.38683824468201267,4.2103839880354075,-0.04871252906513763,-0.2812183777015856,-0.22216432068703482,0.17394576765407171,0.33452611576463864,-0.16372948749216756,-0.6486147893595557,1.434245143990909,-0.16372948749216756,-0.4621081592112762,3.6169723053440874,0.11919997011538998,5.131894866624145,-0.4011890781327106,1.3941514953495935,0.38683824468201267,0.17394576765407171,0.33452611576463864,0.33452611576463864,-0.16372948749216756,-0.22216432068703482,1.3536292924938709,0.06384250748914849,0.38683824468201267,-0.6486147893595557,0.33452611576463864,0.48964847025575964,0.17394576765407171,2.589890921013961,-1.0386067543300004,-2.0378507439803,0.11919997011538998,0.007872098580347686,3.9856208887046614,-0.6486147893595557,-0.6486147893595557,0.38683824468201267,0.007872098580347686,-1.0386067543300004,-0.04871252906513763,-0.22216432068703482,0.38683824468201267,0.8306316454399105,1.434245143990909,1.473918375909616,0.9681807864168185,-0.22216432068703482,0.17394576765407171,-0.8407704557687973,-0.10591263929674817,0.48964847025575964,-0.4621081592112762,0.48964847025575964,-0.7760889340064466,-0.2812183777015856,-0.4011890781327106,-0.16372948749216756,0.38683824468201267,2.5014551385438826,-0.16372948749216756,0.11919997011538998,-0.22216432068703482,3.4391717680711436,-0.16372948749216756,0.06384250748914849,0.48964847025575964,-0.16372948749216756,-0.7760889340064466,-0.4621081592112762,0.228081190180689,-0.34089288926430916,-1.0386067543300004,0.688050566378247,-0.04871252906513763,0.5401492501085412,-0.4011890781327106,-0.6486147893595557,0.2816075367943659,0.2816075367943659,-0.16372948749216756,0.7361572254974664,-1.311278575581721,0.11919997011538998,-0.10591263929674817,0.4385452506124256,-0.34089288926430916,0.17394576765407171,2.410780403978149,-0.4011890781327106,-0.4011890781327106,0.228081190180689,-1.451444818165324,-0.6486147893595557,0.06384250748914849,0.9681807864168185,0.7361572254974664 2937 Liposaccharide metabolic process 9 15 3.10747602885502 0.0018869228751652 P16278,Q99805,P06865,Q9H490,P04062,Q8NBX0,P07686,P04066,P06280 Processes and pathways GO Biological process msigdb_gobp 37,207,16,91,86,60,61,30,31 789,228,86,30,31,16,61,37,1936,60,761,453,2067,207,91 0.33452611576463864,0.9681807864168185,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,2.1898966319486153,3.4162772870291325,-0.2812183777015856,2.222287625540094,0.38683824468201267,0.6393489264185823,-0.34089288926430916,1.057240248022844,1.8491689704918812 2937 Receptor 7 21 3.101845084942281 0.0019231857265187 Q14108,P11717,Q8WTV0,Q9BUN8,Q9UQB8,Q9NR77,Q567V2 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 8,44,14,149,56,57,87 1656,2105,2114,1670,797,44,152,1047,8,2654,87,14,1522,1632,149,2278,57,854,2513,56,512 -0.16372948749216756,-0.4011890781327106,-0.4011890781327106,-0.16372948749216756,0.33452611576463864,2.94951498403428,1.229406481355582,0.17394576765407171,4.712282471751374,-0.8407704557687973,1.8491689704918812,4.192232038011874,-0.04871252906513763,-0.10591263929674817,1.2712655154383892,-0.4621081592112762,2.410780403978149,0.33452611576463864,-0.6486147893595557,2.441260413876219,0.5900489466309929 2937 Secretory granule membrane 22 58 3.0982725355006604 0.001946523323445 P07602,P10253,P42785,Q93050,Q99829,P35613,Q92542,O14975,O75165,P30519,P49755,P13473,Q6IAA8,P11717,Q07065,P11279,Q14165,O15260,Q15363,P46940,Q14254,P01889 Localization GO Cellular component msigdb_gocc 3,129,5,413,286,145,158,266,269,153,274,36,406,44,401,48,309,185,339,215,368,120 2578,1325,266,185,1217,1120,269,2010,2114,1790,120,3,129,2923,48,44,36,2911,1231,153,806,145,1363,5,215,274,1143,1051,1052,2134,1373,972,1256,2399,1603,401,1378,742,2653,309,368,339,2334,448,1273,406,2256,158,413,2664,286,1408,1411,2188,2616,2763,2672,564 -0.7760889340064466,0.007872098580347686,0.8770244243066478,1.101010637080487,0.06384250748914849,0.11919997011538998,0.8770244243066478,-0.34089288926430916,-0.4011890781327106,-0.22216432068703482,1.434245143990909,5.131894866624145,1.3941514953495935,-3.598238387349531,2.618889115071512,2.94951498403428,3.4162772870291325,-2.425443155290095,0.06384250748914849,1.229406481355582,0.33452611576463864,1.2712655154383892,0.007872098580347686,4.863421508907323,1.0129671489863166,0.8770244243066478,0.11919997011538998,0.17394576765407171,0.17394576765407171,-0.4011890781327106,0.007872098580347686,0.228081190180689,0.06384250748914849,-0.5858198190406446,-0.10591263929674817,0.688050566378247,0.007872098580347686,0.38683824468201267,-0.8407704557687973,0.8306316454399105,0.7361572254974664,0.7836800160884329,-0.5236513396667263,0.6393489264185823,0.06384250748914849,0.688050566378247,-0.4621081592112762,1.229406481355582,0.688050566378247,-0.8407704557687973,0.8770244243066478,0.007872098580347686,0.007872098580347686,-0.4011890781327106,-0.7760889340064466,-1.0386067543300004,-0.8407704557687973,0.5401492501085412 2937 Aminoglycan metabolic process 7 14 3.0950260925231485 0.0019679558379801 P16278,P54802,O43505,P06865,P15586,P07686,P04066 Processes and pathways GO Biological process msigdb_gobp 37,42,76,16,20,61,30 76,2110,1670,30,16,61,20,37,42,1062,1715,344,2161,196 1.9547430671585866,-0.4011890781327106,-0.16372948749216756,3.6169723053440874,4.024165938684547,2.1898966319486153,3.887244197186541,3.4162772870291325,3.078582353860239,0.17394576765407171,-0.16372948749216756,0.7836800160884329,-0.4011890781327106,1.101010637080487 2937 SLC superfamily of solute carriers 11 37 3.083640542364779 0.0020448449993681 Q99808,P53985,Q15758,Q8IXU6,Q9Y6M7,P55011,O43772,P08195,Q6NUK1,Q9Y619,O14975 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 99,276,310,6,72,138,12,144,220,127,266 266,12,862,1570,1452,574,1223,144,437,391,1458,807,1922,276,138,1604,1261,310,2727,220,2339,752,6,614,2561,99,1974,688,317,923,693,2188,1200,1767,127,1557,72 0.8770244243066478,4.2103839880354075,0.2816075367943659,-0.10591263929674817,-0.04871252906513763,0.48964847025575964,0.06384250748914849,1.2712655154383892,0.6393489264185823,0.688050566378247,-0.04871252906513763,0.33452611576463864,-0.2812183777015856,0.8770244243066478,1.3126701679029467,-0.10591263929674817,0.06384250748914849,0.8306316454399105,-0.9720282133639213,1.0129671489863166,-0.5236513396667263,0.38683824468201267,4.8486302687541105,0.48964847025575964,-0.7120374352425395,1.7035577277228184,-0.2812183777015856,0.4385452506124256,0.8306316454399105,0.2816075367943659,0.4385452506124256,-0.4011890781327106,0.11919997011538998,-0.16372948749216756,1.434245143990909,-0.04871252906513763,2.057376685439682 2937 serine protease 6 16 3.0659523344278736 0.0021697790204833 Q9HB40,Q9H3G5,P42785,O14773,P10619,P67812 Functions Panther Protein class panther_protein_class 0,1,5,24,58,59 24,58,2716,582,1136,527,5,2130,59,672,85,2415,911,1,0,2670 3.7652112572324823,2.3177619175977977,-0.9720282133639213,0.48964847025575964,0.11919997011538998,0.5401492501085412,4.863421508907323,-0.4011890781327106,2.222287625540094,0.4385452506124256,1.8846964555914798,-0.5858198190406446,0.2816075367943659,5.830215713580066,5.893957451831641,-0.8407704557687973 2937 Coated vesicle 29 81 3.062758326664452 0.0021930709558086 Q8N511,Q15286,Q9BVK6,P04439,O94979,Q14108,Q969M3,Q9Y678,P42892,P61006,P20645,P49257,P49755,P02786,P11717,Q9NVZ3,Q13190,O60493,P50570,P24390,Q15363,P53634,Q12907,P09496,Q5VW38,P51572,Q9Y282,P01889,Q7Z7H5 Localization GO Cellular component msigdb_gocc 131,256,418,128,250,8,284,432,25,395,152,272,274,41,44,320,306,293,303,74,339,203,336,326,88,122,264,120,124 1020,1207,1563,2102,2579,2105,293,1335,517,1219,2114,250,572,951,1670,120,41,128,326,798,2923,2586,1457,44,716,152,74,1141,25,1591,272,274,303,1919,122,1052,2134,1924,203,2899,1147,1925,395,972,1601,818,1062,2721,336,306,1497,8,256,339,745,88,405,1169,124,131,284,1747,418,1408,1760,502,2781,1866,320,2922,1311,2618,1551,1768,1316,264,2293,2001,432,2623,636 0.17394576765407171,0.06384250748914849,-0.10591263929674817,-0.4011890781327106,-0.7760889340064466,-0.4011890781327106,0.8306316454399105,0.007872098580347686,0.5401492501085412,0.06384250748914849,-0.4011890781327106,0.9228702829555585,0.48964847025575964,0.228081190180689,-0.16372948749216756,1.434245143990909,3.1288971739076072,1.3941514953495935,0.7836800160884329,0.33452611576463864,-3.598238387349531,-0.7760889340064466,-0.04871252906513763,2.94951498403428,0.38683824468201267,1.229406481355582,1.9892736116862897,0.11919997011538998,3.744431287238993,-0.10591263929674817,0.8770244243066478,0.8770244243066478,0.8306316454399105,-0.2812183777015856,1.434245143990909,0.17394576765407171,-0.4011890781327106,-0.2812183777015856,1.057240248022844,-2.0378507439803,0.11919997011538998,-0.2812183777015856,0.688050566378247,0.228081190180689,-0.10591263929674817,0.33452611576463864,0.17394576765407171,-0.9720282133639213,0.7836800160884329,0.8306316454399105,-0.04871252906513763,4.712282471751374,0.9228702829555585,0.7836800160884329,0.38683824468201267,1.8491689704918812,0.688050566378247,0.11919997011538998,1.434245143990909,1.3941514953495935,0.8770244243066478,-0.16372948749216756,0.688050566378247,0.007872098580347686,-0.16372948749216756,0.5900489466309929,-1.1058199287517425,-0.22216432068703482,0.8306316454399105,-3.510150275167924,0.06384250748914849,-0.7760889340064466,-0.04871252906513763,-0.16372948749216756,0.06384250748914849,0.9228702829555585,-0.4621081592112762,-0.2812183777015856,0.688050566378247,-0.7760889340064466,0.48964847025575964 2937 Anion transport 17 65 3.055038261036898 0.0022503181228814 Q99808,P07602,P53985,Q15758,Q9Y6M7,O95342,P55011,P08183,Q9UHG3,P51790,P30536,P51798,P08195,Q14728,Q6NUK1,Q9Y619,O75915 Processes and pathways GO Biological process msigdb_gobp 99,3,276,310,72,69,138,13,45,49,82,115,144,177,220,127,213 2100,1437,1443,862,2582,1570,213,69,574,2680,1223,797,3,13,144,2119,437,391,1458,800,523,394,653,82,807,1365,49,115,1922,276,2135,138,2401,1604,1261,1378,1936,1718,177,369,2775,310,984,2334,2727,220,2339,614,2561,685,99,1974,317,923,693,2781,2188,1200,45,2763,1767,2292,2785,127,72 -0.4011890781327106,-0.04871252906513763,-0.04871252906513763,0.2816075367943659,-0.7760889340064466,-0.10591263929674817,1.0129671489863166,2.057376685439682,0.48964847025575964,-0.906083163548422,0.06384250748914849,0.33452611576463864,5.131894866624145,4.192232038011874,1.2712655154383892,-0.4011890781327106,0.6393489264185823,0.688050566378247,-0.04871252906513763,0.33452611576463864,0.5401492501085412,0.688050566378247,0.4385452506124256,1.8846964555914798,0.33452611576463864,0.007872098580347686,2.618889115071512,1.473918375909616,-0.2812183777015856,0.8770244243066478,-0.4011890781327106,1.3126701679029467,-0.5858198190406446,-0.10591263929674817,0.06384250748914849,0.007872098580347686,-0.2812183777015856,-0.16372948749216756,1.1442885584140452,0.7361572254974664,-1.1058199287517425,0.8306316454399105,0.228081190180689,-0.5236513396667263,-0.9720282133639213,1.0129671489863166,-0.5236513396667263,0.48964847025575964,-0.7120374352425395,0.4385452506124256,1.7035577277228184,-0.2812183777015856,0.8306316454399105,0.2816075367943659,0.4385452506124256,-1.1058199287517425,-0.4011890781327106,0.11919997011538998,2.8697220435010813,-1.0386067543300004,-0.16372948749216756,-0.4621081592112762,-1.1058199287517425,1.434245143990909,2.057376685439682 2937 Peptidase activity 20 114 3.0531112784714822 0.002264819363519 Q9HB40,Q9H3G5,Q9UIQ6,P42785,O75844,O14773,Q5JRX3,P42892,Q92542,O75976,P02786,P28072,Q92820,P10619,P67812,P12955,P49721,Q4J6C6,Q99496,Q7Z2K6 Functions GO Molecular function msigdb_gomf 0,1,2,5,19,24,157,25,158,34,41,163,54,58,59,187,78,85,96,98 1562,466,24,468,789,790,2627,19,34,1572,387,2524,2013,41,1029,1128,1583,58,187,582,1682,1901,1134,1233,2635,586,163,1355,1796,1136,1909,1361,527,2885,2927,5,25,2129,2130,1592,78,2474,2476,813,2912,2395,1812,203,1250,663,728,729,59,2930,538,2325,2237,403,1381,2597,672,85,280,157,2248,2751,674,2843,1623,98,2415,1626,1514,680,2889,158,761,54,411,553,1181,2500,285,374,2817,2168,2269,839,496,1530,843,96,2609,2733,286,768,773,1,1983,847,0,2762,1642,851,627,2187,1198,2,2619,380,2515,1016,1652,2516 -0.10591263929674817,0.5900489466309929,3.7652112572324823,0.5900489466309929,0.33452611576463864,0.33452611576463864,-0.8407704557687973,3.926946339483657,3.4391717680711436,-0.10591263929674817,0.688050566378247,-0.7120374352425395,-0.34089288926430916,3.1288971739076072,0.17394576765407171,0.11919997011538998,-0.10591263929674817,2.3177619175977977,1.101010637080487,0.48964847025575964,-0.16372948749216756,-0.2812183777015856,0.11919997011538998,0.06384250748914849,-0.8407704557687973,0.48964847025575964,1.1870839548927827,0.007872098580347686,-0.22216432068703482,0.11919997011538998,-0.2812183777015856,0.007872098580347686,0.5401492501085412,-1.8873708060077286,-4.421251316217688,4.863421508907323,3.744431287238993,-0.4011890781327106,-0.4011890781327106,-0.10591263929674817,1.9547430671585866,-0.6486147893595557,-0.6486147893595557,0.33452611576463864,-2.425443155290095,-0.5858198190406446,-0.22216432068703482,1.057240248022844,0.06384250748914849,0.4385452506124256,0.38683824468201267,0.38683824468201267,2.222287625540094,-6.2325523544671535,0.5401492501085412,-0.5236513396667263,-0.4621081592112762,0.688050566378247,0.007872098580347686,-0.7760889340064466,0.4385452506124256,1.8846964555914798,0.8770244243066478,1.229406481355582,-0.4621081592112762,-1.0386067543300004,0.4385452506124256,-1.451444818165324,-0.10591263929674817,1.7035577277228184,-0.5858198190406446,-0.10591263929674817,-0.04871252906513763,0.4385452506124256,-1.8873708060077286,1.229406481355582,0.38683824468201267,2.5311775269119203,0.688050566378247,0.5401492501085412,0.11919997011538998,-0.6486147893595557,0.8770244243066478,0.7361572254974664,-1.2421547136861633,-0.4011890781327106,-0.4621081592112762,0.33452611576463864,0.5900489466309929,-0.04871252906513763,0.33452611576463864,1.7404982072045598,-0.7760889340064466,-0.9720282133639213,0.8770244243066478,0.38683824468201267,0.38683824468201267,5.830215713580066,-0.2812183777015856,0.33452611576463864,5.893957451831641,-1.0386067543300004,-0.10591263929674817,0.33452611576463864,0.48964847025575964,-0.4011890781327106,0.11919997011538998,5.198840694526526,-0.7760889340064466,0.7361572254974664,-0.6486147893595557,0.228081190180689,-0.10591263929674817,-0.6486147893595557 2937 Cell surface 22 62 3.0476790886622083 0.0023061606255514 P04439,P08183,Q8WTV0,P08195,P26038,P42892,P06576,P02786,P11233,P11717,P11279,P51790,O95342,Q07021,Q12907,O96005,O15258,Q96AC1,Q9Y639,Q14126,Q04721,P01889 Localization GO Cellular component msigdb_gocc 128,13,14,144,270,25,389,41,162,44,48,49,69,444,336,324,322,241,512,487,484,120 322,790,2010,1571,69,324,1893,120,41,2680,128,797,389,2116,1674,2304,13,144,867,954,2923,2586,162,48,44,868,800,1682,1901,2215,270,804,1465,1909,655,2470,25,1367,49,1250,1606,484,444,1378,1935,336,2872,1497,742,1938,487,2334,542,680,14,241,2070,2072,1410,2185,787,512 0.7836800160884329,0.33452611576463864,-0.34089288926430916,-0.10591263929674817,2.057376685439682,0.7836800160884329,-0.2812183777015856,1.434245143990909,3.1288971739076072,-0.906083163548422,1.3941514953495935,0.33452611576463864,0.688050566378247,-0.4011890781327106,-0.16372948749216756,-0.5236513396667263,4.192232038011874,1.2712655154383892,0.2816075367943659,0.228081190180689,-3.598238387349531,-0.7760889340064466,1.1870839548927827,2.618889115071512,2.94951498403428,0.2816075367943659,0.33452611576463864,-0.16372948749216756,-0.2812183777015856,-0.4621081592112762,0.8770244243066478,0.33452611576463864,-0.04871252906513763,-0.2812183777015856,0.4385452506124256,-0.6486147893595557,3.744431287238993,0.007872098580347686,2.618889115071512,0.06384250748914849,-0.10591263929674817,0.5900489466309929,0.6393489264185823,0.007872098580347686,-0.2812183777015856,0.7836800160884329,-1.6665070292939557,-0.04871252906513763,0.38683824468201267,-0.2812183777015856,0.5900489466309929,-0.5236513396667263,0.5401492501085412,0.4385452506124256,4.192232038011874,0.9681807864168185,-0.34089288926430916,-0.34089288926430916,0.007872098580347686,-0.4011890781327106,0.38683824468201267,0.5900489466309929 2937 Exogenous protein binding 7 13 3.0460291040329763 0.0023188538824043 P78310,Q14108,P02786,Q8WTV0,O15118,P11279,P35613 Functions GO Molecular function msigdb_gomf 188,8,41,14,75,48,145 75,41,797,952,1456,1678,48,1682,145,188,8,310,14 1.9547430671585866,3.1288971739076072,0.33452611576463864,0.228081190180689,-0.04871252906513763,-0.16372948749216756,2.618889115071512,-0.16372948749216756,1.2712655154383892,1.101010637080487,4.712282471751374,0.8306316454399105,4.192232038011874 2937 Host cell receptor for virus entry 7 13 3.0460291040329763 0.0023188538824043 P78310,Q14108,P02786,Q8WTV0,O15118,P11279,P35613 Functions Protein Atlas Molecular function protein_atlas_molecular_function 188,8,41,14,75,48,145 75,41,797,952,1456,1678,48,1682,145,188,8,310,14 1.9547430671585866,3.1288971739076072,0.33452611576463864,0.228081190180689,-0.04871252906513763,-0.16372948749216756,2.618889115071512,-0.16372948749216756,1.2712655154383892,1.101010637080487,4.712282471751374,0.8306316454399105,4.192232038011874 2937 Increased bone mineral density 6 23 3.044554017207433 0.0023302557958189 Q14739,Q15392,Q14108,P54802,Q15125,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,71,8,42,26,86 1894,86,1684,1794,1905,1463,2684,2034,115,42,2478,1150,2594,1494,8,35,1503,26,71,1165,2287,1996,2802 -0.2812183777015856,1.8491689704918812,-0.16372948749216756,-0.22216432068703482,-0.2812183777015856,-0.04871252906513763,-0.906083163548422,-0.34089288926430916,1.473918375909616,3.078582353860239,-0.6486147893595557,0.11919997011538998,-0.7760889340064466,-0.04871252906513763,4.712282471751374,3.4391717680711436,-0.04871252906513763,3.7024803541208557,2.057376685439682,0.11919997011538998,-0.4621081592112762,-0.2812183777015856,-1.1736688722168886 2937 Hepatosplenomegaly 10 37 3.0436154964439224 0.0023375369393425 O75845,Q14739,P16278,P38571,P51798,Q9Y285,Q13510,P10619,P04062,P07686 Drugs and Diseases Human Phenotype Ontology msigdb_hp 212,35,37,17,115,119,55,58,86,61 1020,228,1890,212,86,2206,61,58,437,37,1586,804,657,2314,17,2471,1803,1473,1248,1920,115,2643,1932,443,2691,55,826,35,2796,1289,346,1767,2093,119,1319,1878,2711 0.17394576765407171,0.9681807864168185,-0.2812183777015856,1.0129671489863166,1.8491689704918812,-0.4621081592112762,2.1898966319486153,2.3177619175977977,0.6393489264185823,3.4162772870291325,-0.10591263929674817,0.33452611576463864,0.4385452506124256,-0.5236513396667263,3.9856208887046614,-0.6486147893595557,-0.22216432068703482,-0.04871252906513763,0.06384250748914849,-0.2812183777015856,1.473918375909616,-0.8407704557687973,-0.2812183777015856,0.6393489264185823,-0.906083163548422,2.5014551385438826,0.33452611576463864,3.4391717680711436,-1.1736688722168886,0.06384250748914849,0.7836800160884329,-0.16372948749216756,-0.34089288926430916,1.473918375909616,0.06384250748914849,-0.22216432068703482,-0.906083163548422 2937 Lipid biosynthetic process 25 120 3.0435158840860037 0.0023383109642913 Q8WTV0,Q8NCC3,Q15125,Q16850,O14975,Q14739,Q9UBM7,Q9H7Z7,P35610,O00763,Q13510,Q8NBX0,P07686,Q6UWP7,Q15392,O95342,Q99805,O95674,P30536,Q9H490,P04062,O75845,Q96N66,O60762,Q06136 Processes and pathways GO Biological process msigdb_gobp 14,15,26,27,266,35,38,181,53,292,55,60,61,192,71,69,207,323,82,91,86,212,242,228,234 1324,637,1563,292,2447,266,1438,1022,2198,789,2380,228,2010,212,948,1573,69,1343,2203,323,2014,795,796,2457,86,2680,1895,61,799,1034,800,521,1230,2387,1352,1901,2023,2634,2462,2466,653,82,2861,53,332,2314,588,2771,2472,2391,2034,1367,2744,1701,2687,1709,1932,234,538,485,1936,55,2750,827,2146,35,1382,26,1833,1614,71,1615,1067,2054,2333,27,404,489,2487,192,1078,2253,679,60,15,2256,14,410,1394,837,761,453,242,2562,1751,2067,416,2501,207,2734,500,1978,1406,2275,2177,1002,91,181,2081,927,2088,696,630,2616,38,1107,1425,2763,2441,1558 0.007872098580347686,0.4385452506124256,-0.10591263929674817,0.8306316454399105,-0.6486147893595557,0.8770244243066478,-0.04871252906513763,0.17394576765407171,-0.4621081592112762,0.33452611576463864,-0.5858198190406446,0.9681807864168185,-0.34089288926430916,1.0129671489863166,0.228081190180689,-0.10591263929674817,2.057376685439682,0.007872098580347686,-0.4621081592112762,0.7836800160884329,-0.34089288926430916,0.33452611576463864,0.33452611576463864,-0.6486147893595557,1.8491689704918812,-0.906083163548422,-0.2812183777015856,2.1898966319486153,0.33452611576463864,0.17394576765407171,0.33452611576463864,0.5401492501085412,0.06384250748914849,-0.5858198190406446,0.007872098580347686,-0.2812183777015856,-0.34089288926430916,-0.8407704557687973,-0.6486147893595557,-0.6486147893595557,0.4385452506124256,1.8846964555914798,-1.5941764518204824,2.589890921013961,0.7836800160884329,-0.5236513396667263,0.48964847025575964,-1.1058199287517425,-0.6486147893595557,-0.5858198190406446,-0.34089288926430916,0.007872098580347686,-1.0386067543300004,-0.16372948749216756,-0.906083163548422,-0.16372948749216756,-0.2812183777015856,0.9681807864168185,0.5401492501085412,0.5900489466309929,-0.2812183777015856,2.5014551385438826,-1.0386067543300004,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,-0.10591263929674817,2.057376685439682,-0.10591263929674817,0.17394576765407171,-0.34089288926430916,-0.5236513396667263,3.7024803541208557,0.688050566378247,0.5900489466309929,-0.6486147893595557,1.101010637080487,0.17394576765407171,-0.4621081592112762,0.4385452506124256,2.222287625540094,4.0999276525600274,-0.4621081592112762,4.192232038011874,0.688050566378247,0.007872098580347686,0.33452611576463864,0.38683824468201267,0.6393489264185823,0.9681807864168185,-0.7120374352425395,-0.16372948749216756,-0.34089288926430916,0.688050566378247,-0.6486147893595557,1.057240248022844,-0.9720282133639213,0.5900489466309929,-0.2812183777015856,0.007872098580347686,-0.4621081592112762,-0.4011890781327106,0.228081190180689,1.8491689704918812,1.1442885584140452,-0.34089288926430916,0.2816075367943659,-0.34089288926430916,0.4385452506124256,0.48964847025575964,-0.7760889340064466,3.4162772870291325,0.17394576765407171,0.007872098580347686,-1.0386067543300004,-0.5858198190406446,-0.04871252906513763 2937 Endocytic vesicle membrane 14 36 3.041387881445889 0.0023549024983178 Q15286,P04439,P13473,Q93050,Q14108,P02786,P11717,Q8WTV0,P11279,P01889,Q9Y487,Q5KU26,P20645,P50570 Localization GO Cellular component msigdb_gocc 256,128,36,413,8,41,44,14,48,120,430,28,152,303 2578,1219,2114,1670,120,41,128,2923,48,44,36,716,152,804,303,1051,1052,2899,395,1373,1149,818,1062,1719,1498,2653,8,256,1725,984,28,14,413,1747,1638,430 -0.7760889340064466,0.06384250748914849,-0.4011890781327106,-0.16372948749216756,1.434245143990909,3.1288971739076072,1.3941514953495935,-3.598238387349531,2.618889115071512,2.94951498403428,3.4162772870291325,0.38683824468201267,1.229406481355582,0.33452611576463864,0.8306316454399105,0.17394576765407171,0.17394576765407171,-2.0378507439803,0.688050566378247,0.007872098580347686,0.11919997011538998,0.33452611576463864,0.17394576765407171,-0.16372948749216756,-0.04871252906513763,-0.8407704557687973,4.712282471751374,0.9228702829555585,-0.16372948749216756,0.228081190180689,3.681306413452911,4.192232038011874,0.688050566378247,-0.16372948749216756,-0.10591263929674817,0.688050566378247 2937 Steroid biosynthetic process 7 43 3.036628645067762 0.0023923999628152 Q14739,Q9UBM7,Q15392,O95342,Q13510,Q15125,Q16850 Processes and pathways GO Biological process msigdb_gobp 35,38,71,69,55,26,27 266,212,1573,69,2457,1895,799,521,1230,1352,2023,2634,2462,653,82,332,2472,2391,1701,1709,1932,1936,55,827,2146,35,1382,26,1833,71,1615,1067,2054,27,489,1394,416,2501,2275,1002,38,1425,2763 0.8770244243066478,1.0129671489863166,-0.10591263929674817,2.057376685439682,-0.6486147893595557,-0.2812183777015856,0.33452611576463864,0.5401492501085412,0.06384250748914849,0.007872098580347686,-0.34089288926430916,-0.8407704557687973,-0.6486147893595557,0.4385452506124256,1.8846964555914798,0.7836800160884329,-0.6486147893595557,-0.5858198190406446,-0.16372948749216756,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,2.5014551385438826,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.10591263929674817,0.17394576765407171,-0.34089288926430916,3.7024803541208557,0.5900489466309929,0.007872098580347686,0.688050566378247,-0.6486147893595557,-0.4621081592112762,0.228081190180689,3.4162772870291325,0.007872098580347686,-1.0386067543300004 2937 Regulation of lipid metabolic process 7 42 3.027091487410137 0.0024691921376225 P07602,Q9UBM7,O95342,Q8WTV0,O75844,Q13510,P61916 Processes and pathways GO Biological process msigdb_gobp 3,38,69,14,19,55,62 292,2380,708,1337,19,948,1573,69,2203,2680,1895,3,1034,1352,1901,82,2469,2314,588,2744,877,2687,1599,62,2649,1936,55,2750,2824,1615,406,2256,14,837,242,2070,2188,38,1107,1425,2090,1873 0.8306316454399105,-0.5858198190406446,0.38683824468201267,0.007872098580347686,3.926946339483657,0.228081190180689,-0.10591263929674817,2.057376685439682,-0.4621081592112762,-0.906083163548422,-0.2812183777015856,5.131894866624145,0.17394576765407171,0.007872098580347686,-0.2812183777015856,1.8846964555914798,-0.6486147893595557,-0.5236513396667263,0.48964847025575964,-1.0386067543300004,0.2816075367943659,-0.906083163548422,-0.10591263929674817,2.157214859958303,-0.8407704557687973,-0.2812183777015856,2.5014551385438826,-1.0386067543300004,-1.311278575581721,-0.10591263929674817,0.688050566378247,-0.4621081592112762,4.192232038011874,0.33452611576463864,0.9681807864168185,-0.34089288926430916,-0.4011890781327106,3.4162772870291325,0.17394576765407171,0.007872098580347686,-0.34089288926430916,-0.22216432068703482 2937 Cation transmembrane transporter activity 20 59 3.021621785477291 0.0025142447816486 Q93050,P55011,O43772,Q9Y487,P08195,P06576,P12235,Q9UM00,Q15758,P51790,P24539,O75947,Q9Y6M7,O75964,P98194,P56385,Q99808,Q13423,Q9Y619,Q9HD20 Functions GO Molecular function msigdb_gomf 413,138,12,430,144,389,391,172,310,49,299,296,72,77,204,334,99,117,127,262 12,862,296,77,1452,2458,1895,1223,389,2304,1896,144,1581,579,391,438,1900,957,1686,1687,961,869,299,2215,807,2029,1692,967,2127,724,2743,49,138,2038,334,1149,1483,204,1604,2480,117,310,2334,752,2498,549,1293,413,2561,99,923,693,262,1422,2782,172,430,127,72 4.2103839880354075,0.2816075367943659,0.8306316454399105,1.9547430671585866,-0.04871252906513763,-0.6486147893595557,-0.2812183777015856,0.06384250748914849,0.688050566378247,-0.5236513396667263,-0.2812183777015856,1.2712655154383892,-0.10591263929674817,0.48964847025575964,0.688050566378247,0.6393489264185823,-0.2812183777015856,0.228081190180689,-0.16372948749216756,-0.16372948749216756,0.228081190180689,0.2816075367943659,0.8306316454399105,-0.4621081592112762,0.33452611576463864,-0.34089288926430916,-0.16372948749216756,0.228081190180689,-0.4011890781327106,0.38683824468201267,-1.0386067543300004,2.618889115071512,1.3126701679029467,-0.34089288926430916,0.7836800160884329,0.11919997011538998,-0.04871252906513763,1.057240248022844,-0.10591263929674817,-0.6486147893595557,1.473918375909616,0.8306316454399105,-0.5236513396667263,0.38683824468201267,-0.6486147893595557,0.5401492501085412,0.06384250748914849,0.688050566378247,-0.7120374352425395,1.7035577277228184,0.2816075367943659,0.4385452506124256,0.9228702829555585,0.007872098580347686,-1.1058199287517425,1.1870839548927827,0.688050566378247,1.434245143990909,2.057376685439682 2937 Anion transmembrane transport 15 40 3.0146696515916704 0.0025725929002036 P12235,P53985,Q15758,Q9Y6M7,P55011,Q9H2D1,P08183,Q9UHG3,Q15041,P51790,P51798,P08195,Q14728,Q9Y619,O75915 Processes and pathways GO Biological process msigdb_gobp 391,276,310,72,138,317,13,45,369,49,115,144,177,127,213 862,2582,1570,213,574,1223,797,13,144,391,1458,394,807,1365,49,115,1922,276,138,1604,1261,1718,177,369,310,2334,614,2561,1974,317,923,693,2781,1200,45,1767,2292,2785,127,72 0.2816075367943659,-0.7760889340064466,-0.10591263929674817,1.0129671489863166,0.48964847025575964,0.06384250748914849,0.33452611576463864,4.192232038011874,1.2712655154383892,0.688050566378247,-0.04871252906513763,0.688050566378247,0.33452611576463864,0.007872098580347686,2.618889115071512,1.473918375909616,-0.2812183777015856,0.8770244243066478,1.3126701679029467,-0.10591263929674817,0.06384250748914849,-0.16372948749216756,1.1442885584140452,0.7361572254974664,0.8306316454399105,-0.5236513396667263,0.48964847025575964,-0.7120374352425395,-0.2812183777015856,0.8306316454399105,0.2816075367943659,0.4385452506124256,-1.1058199287517425,0.11919997011538998,2.8697220435010813,-0.16372948749216756,-0.4621081592112762,-1.1058199287517425,1.434245143990909,2.057376685439682 2937 Increased susceptibility to fractures 10 49 3.007770943941356 0.0026317141360359 Q14739,P52788,Q14108,Q96AY3,Q32P28,P51798,Q9H4A3,P04062,P48735,Q96L58 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,70,8,105,80,115,160,86,216,196 1778,1437,1022,2198,1118,707,2299,212,948,1787,1892,796,1790,86,2206,1127,1454,1674,2527,714,1352,1132,1462,1586,2531,1468,1360,2471,2885,216,115,70,2478,484,1494,826,8,35,1944,80,1517,551,105,196,1859,1538,160,2186,1996 -0.22216432068703482,-0.04871252906513763,0.17394576765407171,-0.4621081592112762,0.11919997011538998,0.38683824468201267,-0.5236513396667263,1.0129671489863166,0.228081190180689,-0.22216432068703482,-0.2812183777015856,0.33452611576463864,-0.22216432068703482,1.8491689704918812,-0.4621081592112762,0.11919997011538998,-0.04871252906513763,-0.16372948749216756,-0.7120374352425395,0.38683824468201267,0.007872098580347686,0.11919997011538998,-0.04871252906513763,-0.10591263929674817,-0.7120374352425395,-0.04871252906513763,0.007872098580347686,-0.6486147893595557,-1.8873708060077286,1.0129671489863166,1.473918375909616,2.057376685439682,-0.6486147893595557,0.5900489466309929,-0.04871252906513763,0.33452611576463864,4.712282471751374,3.4391717680711436,-0.2812183777015856,1.919885894471246,-0.04871252906513763,0.5401492501085412,1.628562285011634,1.101010637080487,-0.22216432068703482,-0.04871252906513763,1.229406481355582,-0.4011890781327106,-0.2812183777015856 2937 Protein targeting 16 96 3.0057002840731686 0.0026497003067669 O60830,Q99496,Q15785,P13473,O60725,Q14108,P40855,P30536,Q99595,P20645,P51572,Q5JRX3,Q15629,Q8N4H5,Q9NS69,P43307 Processes and pathways GO Biological process msigdb_gobp 32,96,130,36,102,8,164,82,90,152,122,157,156,92,29,121 1114,939,1020,1115,1436,943,1213,1443,2106,102,32,2627,950,2382,1668,2629,1575,1028,575,297,713,1455,2585,2586,1457,36,801,152,1464,2682,82,526,2469,656,1691,1470,164,121,1050,272,1051,122,663,174,2720,729,594,1483,1057,1704,1707,1487,1822,2480,538,2872,1936,8,2597,369,541,156,130,604,2600,2487,157,1843,2342,2156,1624,1172,92,2162,96,90,2733,2435,29,2086,2918,1198,1549,1423,1313,1107,1011,2368,1014,634,2622,2785,1113,1776,463,1320 0.11919997011538998,0.228081190180689,0.17394576765407171,0.11919997011538998,-0.04871252906513763,0.228081190180689,0.06384250748914849,-0.04871252906513763,-0.4011890781327106,1.628562285011634,3.59525158154659,-0.8407704557687973,0.228081190180689,-0.5858198190406446,-0.16372948749216756,-0.8407704557687973,-0.10591263929674817,0.17394576765407171,0.48964847025575964,0.8306316454399105,0.38683824468201267,-0.04871252906513763,-0.7760889340064466,-0.7760889340064466,-0.04871252906513763,3.4162772870291325,0.33452611576463864,1.229406481355582,-0.04871252906513763,-0.906083163548422,1.8846964555914798,0.5401492501085412,-0.6486147893595557,0.4385452506124256,-0.16372948749216756,-0.04871252906513763,1.1870839548927827,1.434245143990909,0.17394576765407171,0.8770244243066478,0.17394576765407171,1.434245143990909,0.4385452506124256,1.1442885584140452,-0.9720282133639213,0.38683824468201267,0.48964847025575964,-0.04871252906513763,0.17394576765407171,-0.16372948749216756,-0.16372948749216756,-0.04871252906513763,-0.22216432068703482,-0.6486147893595557,0.5401492501085412,-1.6665070292939557,-0.2812183777015856,4.712282471751374,-0.7760889340064466,0.7361572254974664,0.5401492501085412,1.229406481355582,1.3941514953495935,0.48964847025575964,-0.7760889340064466,-0.6486147893595557,1.229406481355582,-0.22216432068703482,-0.5236513396667263,-0.4011890781327106,-0.10591263929674817,0.11919997011538998,1.8132975124314339,-0.4011890781327106,1.7404982072045598,1.8491689704918812,-0.9720282133639213,-0.5858198190406446,3.681306413452911,-0.34089288926430916,-2.9956170913795845,0.11919997011538998,-0.04871252906513763,0.007872098580347686,0.06384250748914849,0.17394576765407171,0.228081190180689,-0.5236513396667263,0.228081190180689,0.48964847025575964,-0.7760889340064466,-1.1058199287517425,0.17394576765407171,-0.16372948749216756,0.6393489264185823,0.06384250748914849 2937 Skeletal dysplasia 18 38 2.9944146938177987 0.0027497193527017 O95831,P51648,Q14739,P10619,P16278,Q96HY6,P21359,P40855,Q9UBN7,P36776,Q8WWQ0,O15160,P56589,O96011,Q13428,Q04721,Q96L58,Q9H1A4 Drugs and Diseases Human Phenotype Ontology msigdb_hp 575,275,35,58,37,346,523,164,210,527,551,467,174,355,540,484,196,260 1563,467,1663,575,355,1674,58,37,1905,523,1907,527,2315,164,275,174,594,484,1607,540,35,983,1269,745,1735,551,1852,346,196,1091,260,1540,1986,2182,851,210,1996,2709 -0.10591263929674817,0.5900489466309929,-0.16372948749216756,0.48964847025575964,0.7361572254974664,-0.16372948749216756,2.3177619175977977,3.4162772870291325,-0.2812183777015856,0.5401492501085412,-0.2812183777015856,0.5401492501085412,-0.5236513396667263,1.1870839548927827,0.8770244243066478,1.1442885584140452,0.48964847025575964,0.5900489466309929,-0.10591263929674817,0.5401492501085412,3.4391717680711436,0.228081190180689,0.06384250748914849,0.38683824468201267,-0.16372948749216756,0.5401492501085412,-0.22216432068703482,0.7836800160884329,1.101010637080487,0.17394576765407171,0.9228702829555585,-0.04871252906513763,-0.2812183777015856,-0.4011890781327106,0.33452611576463864,1.057240248022844,-0.2812183777015856,-0.906083163548422 2937 Carboxypeptidase activity 6 12 2.992515429154601 0.0027668868066252 Q9HB40,Q9H3G5,O75976,P42785,P12955,P10619 Functions GO Molecular function msigdb_gomf 0,1,34,5,187,58 34,58,187,1796,1361,5,2237,1514,496,286,1,0 3.4391717680711436,2.3177619175977977,1.101010637080487,-0.22216432068703482,0.007872098580347686,4.863421508907323,-0.4621081592112762,-0.04871252906513763,0.5900489466309929,0.8770244243066478,5.830215713580066,5.893957451831641 2937 Ceramide metabolic process 6 15 2.991153980875319 0.0027792531202628 Q8NCC3,P06865,Q13510,P04062,P07686,P06280 Processes and pathways GO Biological process msigdb_gobp 15,16,55,86,61,31 1022,2198,1343,86,31,16,61,1237,1936,55,2487,679,15,207,2088 0.17394576765407171,-0.4621081592112762,0.007872098580347686,1.8491689704918812,3.6169723053440874,4.024165938684547,2.1898966319486153,0.06384250748914849,-0.2812183777015856,2.5014551385438826,-0.6486147893595557,0.4385452506124256,4.0999276525600274,1.057240248022844,-0.34089288926430916 2937 Progressive neurologic deterioration 6 19 2.988947406850265 0.0027994031357925 P07602,P16278,P54802,P04062,P07686,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,37,42,86,61,95 1443,86,3,61,95,37,133,1688,2534,1245,42,1815,2478,538,2051,987,1949,2501,2188 -0.04871252906513763,1.8491689704918812,5.131894866624145,2.1898966319486153,1.7404982072045598,3.4162772870291325,1.3536292924938709,-0.16372948749216756,-0.7120374352425395,0.06384250748914849,3.078582353860239,-0.22216432068703482,-0.6486147893595557,0.5401492501085412,-0.34089288926430916,0.228081190180689,-0.2812183777015856,-0.6486147893595557,-0.4011890781327106 2937 Abnormal systemic blood pressure 13 88 2.9879045312349928 0.0028089728305742 P07602,P20700,O43772,P38571,O75844,P35610,Q13423,P42892,P04062,P01889,P07686,P15289,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,133,12,17,19,53,117,25,86,120,61,95,31 939,1443,705,12,269,1569,19,1787,2458,120,1894,86,1345,2206,31,3,61,642,2017,2118,714,95,1352,1132,133,523,1688,802,1586,2466,804,653,2534,2637,2589,2684,53,1044,2741,1361,1469,17,2885,2742,1473,25,1590,2317,1147,1150,1261,443,736,484,2749,1490,538,739,117,2691,1609,1065,1265,1612,1503,603,1729,1276,2700,1746,411,1967,2856,498,2798,160,1004,2762,2669,2509,2188,1991,2287,785,1996,2802,382,2905 0.228081190180689,-0.04871252906513763,0.38683824468201267,4.2103839880354075,0.8770244243066478,-0.10591263929674817,3.926946339483657,-0.22216432068703482,-0.6486147893595557,1.434245143990909,-0.2812183777015856,1.8491689704918812,0.007872098580347686,-0.4621081592112762,3.6169723053440874,5.131894866624145,2.1898966319486153,0.4385452506124256,-0.34089288926430916,-0.4011890781327106,0.38683824468201267,1.7404982072045598,0.007872098580347686,0.11919997011538998,1.3536292924938709,0.5401492501085412,-0.16372948749216756,0.33452611576463864,-0.10591263929674817,-0.6486147893595557,0.33452611576463864,0.4385452506124256,-0.7120374352425395,-0.8407704557687973,-0.7760889340064466,-0.906083163548422,2.589890921013961,0.17394576765407171,-1.0386067543300004,0.007872098580347686,-0.04871252906513763,3.9856208887046614,-1.8873708060077286,-1.0386067543300004,-0.04871252906513763,3.744431287238993,-0.10591263929674817,-0.5236513396667263,0.11919997011538998,0.11919997011538998,0.06384250748914849,0.6393489264185823,0.38683824468201267,0.5900489466309929,-1.0386067543300004,-0.04871252906513763,0.5401492501085412,0.38683824468201267,1.473918375909616,-0.906083163548422,-0.10591263929674817,0.17394576765407171,0.06384250748914849,-0.10591263929674817,-0.04871252906513763,0.48964847025575964,-0.16372948749216756,0.06384250748914849,-0.906083163548422,-0.16372948749216756,0.688050566378247,-0.2812183777015856,-1.5224894117754426,0.5900489466309929,-1.1736688722168886,1.229406481355582,0.228081190180689,-1.0386067543300004,-0.8407704557687973,-0.6486147893595557,-0.4011890781327106,-0.2812183777015856,-0.4621081592112762,0.38683824468201267,-0.2812183777015856,-1.1736688722168886,0.7361572254974664,-2.1909305126679395 2937 Vesicle membrane 60 204 2.9862873459135533 0.002823871633941 Q8N511,Q9UIQ6,P07602,P10253,P42785,P04439,Q969E2,Q14108,P55011,Q15286,O94979,O14828,Q93050,Q8WTV0,Q99829,P35613,Q9Y487,Q9Y678,Q92542,P42892,P61006,O14975,Q5KU26,P20645,O75165,Q96SU4,P30519,P49257,P49755,O15400,P13473,O43795,Q7Z3U7,Q6IAA8,P02786,P11233,P11717,Q9H4M9,Q9NVZ3,P11279,P51790,Q14165,Q13190,O60493,Q14728,Q8IV08,P50570,O15260,O95342,Q9UNH7,P24390,Q99805,O15118,Q15363,P09496,P46940,Q14254,O15127,O15498,P01889 Localization GO Cellular component msigdb_gocc 131,2,3,129,5,128,135,8,138,256,250,249,413,14,286,145,430,432,158,25,395,266,28,152,269,416,153,272,274,383,36,385,311,406,41,162,44,318,320,48,49,309,306,293,177,63,303,185,69,352,74,207,75,339,326,215,368,113,227,120 2624,1114,2578,1020,1325,1207,1326,2102,1115,249,266,2579,75,113,185,383,227,1660,2105,1116,385,293,1217,1218,570,1335,2582,1120,269,517,1219,2831,2010,2832,2114,250,69,951,1670,1790,120,41,2680,128,797,2304,3,1896,326,798,129,2923,1457,162,48,44,36,2911,1686,1231,2022,716,152,1232,74,804,1909,153,806,1141,145,1363,2885,2771,659,5,875,25,215,1591,272,274,303,1143,1051,1919,49,1052,2134,1924,2899,1147,138,1925,395,1373,972,1149,1256,1601,1059,1708,818,2399,1603,1062,401,1378,823,306,1718,1719,1498,742,1158,2750,2653,8,309,368,177,1382,256,1725,339,745,984,2334,28,448,1273,2337,406,1169,1624,311,63,2498,131,2256,14,615,158,682,413,135,2664,1747,2562,498,416,998,207,2174,286,1531,1976,2074,1408,1638,2760,1760,502,318,2781,1411,1866,852,320,2866,2188,697,2616,2922,2284,1009,1548,1311,1312,2618,2859,2763,2,1551,1768,1770,2574,1316,702,2368,2708,352,935,2442,2672,1014,2293,430,2711,2001,432,2623,564,636 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2937 Platyspondyly 10 31 2.983308293745516 0.0028515060795479 Q96HY6,Q14739,P16278,Q9UBN7,Q96AY3,Q32P28,Q6NUK1,P48735,Q96L58,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 346,35,37,210,105,80,220,216,196,30 1778,1118,1663,948,575,30,37,1905,2531,964,1468,216,970,2042,1931,2691,35,983,80,986,220,449,343,1280,105,346,196,1986,851,210,1649 -0.22216432068703482,0.11919997011538998,-0.16372948749216756,0.228081190180689,0.48964847025575964,3.6169723053440874,3.4162772870291325,-0.2812183777015856,-0.7120374352425395,0.228081190180689,-0.04871252906513763,1.0129671489863166,0.228081190180689,-0.34089288926430916,-0.2812183777015856,-0.906083163548422,3.4391717680711436,0.228081190180689,1.919885894471246,0.228081190180689,1.0129671489863166,0.6393489264185823,0.7836800160884329,0.06384250748914849,1.628562285011634,0.7836800160884329,1.101010637080487,-0.2812183777015856,0.33452611576463864,1.057240248022844,-0.10591263929674817 2937 Lipid homeostasis 11 22 2.98225826005702 0.0028613051594976 O15260,O95342,Q9UHB6,Q5BJF2,Q9H4M9,Q8WTV0,Q9NQC3,O15118,P35610,P61916,P17174 Processes and pathways GO Biological process msigdb_gobp 185,69,377,11,318,14,208,75,53,62,151 1882,75,2376,185,69,151,1038,53,62,485,1936,1832,11,406,14,1407,318,208,377,1872,2623,1557 -0.2812183777015856,1.9547430671585866,-0.5858198190406446,1.101010637080487,2.057376685439682,1.229406481355582,0.17394576765407171,2.589890921013961,2.157214859958303,0.5900489466309929,-0.2812183777015856,-0.22216432068703482,4.2819961355673675,0.688050566378247,4.192232038011874,0.007872098580347686,0.8306316454399105,1.057240248022844,0.7361572254974664,-0.22216432068703482,-0.7760889340064466,-0.04871252906513763 2937 Corneal opacity 14 46 2.9797112164673245 0.0028852024327645 O75845,P16278,Q9UBM7,Q06136,P40855,O43505,O75844,Q13510,P56589,Q6NUK1,P10619,P04062,P04066,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 212,37,38,234,164,76,19,55,174,220,58,86,30,31 942,76,2902,2450,1886,1663,2787,19,212,1787,1452,355,2015,1790,1894,86,30,31,2459,58,37,1684,1794,2684,164,275,1482,2924,1815,174,1150,234,1715,1156,55,1503,603,1165,220,675,1746,1982,2360,38,2287,2802 0.228081190180689,1.9547430671585866,-2.114065123664798,-0.6486147893595557,-0.2812183777015856,-0.16372948749216756,-1.1736688722168886,3.926946339483657,1.0129671489863166,-0.22216432068703482,-0.04871252906513763,0.7361572254974664,-0.34089288926430916,-0.22216432068703482,-0.2812183777015856,1.8491689704918812,3.6169723053440874,3.6169723053440874,-0.6486147893595557,2.3177619175977977,3.4162772870291325,-0.16372948749216756,-0.22216432068703482,-0.906083163548422,1.1870839548927827,0.8770244243066478,-0.04871252906513763,-3.598238387349531,-0.22216432068703482,1.1442885584140452,0.11919997011538998,0.9681807864168185,-0.16372948749216756,0.11919997011538998,2.5014551385438826,-0.04871252906513763,0.48964847025575964,0.11919997011538998,1.0129671489863166,0.4385452506124256,-0.16372948749216756,-0.2812183777015856,-0.5236513396667263,3.4162772870291325,-0.4621081592112762,-1.1736688722168886 2937 Membrane lipid catabolic process 6 10 2.979267955604279 0.0028893798286879 P06865,P50897,Q13510,P07686,P04066,P06280 Processes and pathways GO Biological process msigdb_gobp 16,22,55,61,30,31 1343,86,30,31,16,61,22,55,243,2088 0.007872098580347686,1.8491689704918812,3.6169723053440874,3.6169723053440874,4.024165938684547,2.1898966319486153,3.8063874677803375,2.5014551385438826,0.9681807864168185,-0.34089288926430916 2937 Incoordination 8 67 2.9755219349775075 0.0029249043182375 P07602,O75503,Q13510,O14773,Q9NR77,Q9Y619,P04062,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,4,55,24,57,127,86,95 1434,24,942,1443,706,269,517,4,2112,1668,1787,86,1454,3,391,2021,95,1688,1907,2534,1690,1471,1244,875,1917,2474,1593,1922,971,2478,2540,2643,1057,123,736,2046,538,55,980,669,1832,1163,2409,492,2410,1276,2553,1172,1519,2257,1746,1292,1968,498,997,622,2501,2508,57,929,2188,1010,2189,507,1107,1556,127 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2937 Neutrophil degranulation 28 159 2.9717065457626126 0.0029614959853383 P07602,P10253,P42785,P04439,P15586,Q92542,P04066,P06280,P30519,P13473,P16278,P42025,Q14004,P11717,Q9H7Z7,P11279,Q9BTY2,Q92820,Q13510,P10619,P07686,P61916,Q13442,O15260,P53634,P15289,P68402,P01889 Processes and pathways Reactome Pathways msigdb_reactome 3,129,5,128,20,158,30,31,153,36,37,165,166,44,181,48,52,54,55,58,61,62,67,185,203,95,106,120 2578,940,1561,1325,466,1882,266,185,515,1443,1217,1120,269,948,2114,2383,2457,1221,1790,120,30,1672,1576,128,31,712,578,2304,1128,1580,3,61,642,713,867,357,954,1583,2209,1678,129,2923,58,1457,2528,48,44,2529,1227,1680,36,2021,582,800,1899,2884,95,20,2911,37,2717,958,393,1685,1134,2588,2467,2125,872,1466,153,2218,1801,1242,1362,1470,1363,165,5,215,660,812,1479,1143,1051,813,1701,2134,203,2478,1373,972,1703,1256,62,2399,595,106,1151,1603,1489,401,1378,2236,1063,1064,2690,67,55,742,2653,668,166,1160,309,669,1830,1268,2873,2334,448,1273,406,2777,1172,908,2926,1518,2256,158,54,413,2664,1963,619,1749,843,2608,686,2351,286,2072,52,2354,1408,1098,181,1411,1100,2829,2188,2616,562,1551,2092,1772,1013,2672,564 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2937 Hepatomegaly 34 159 2.959496491051572 0.0030814221107768 P07602,P10253,Q14108,O43772,Q14376,P38571,P15586,P04066,Q14739,P16278,P40855,P54802,Q9BT22,O43676,P35610,P09601,Q13510,P56589,P05165,P07686,P61916,Q96HY6,P12955,O95342,O15118,Q13426,P19404,P04062,P33991,Q99496,O75845,P51798,O60762,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,129,8,12,147,17,20,30,35,37,164,42,316,46,53,173,55,174,298,61,62,346,187,69,75,337,328,86,330,96,212,115,228,127 1020,1563,1115,75,46,12,228,707,1336,1446,517,709,2009,1664,518,1783,1890,212,1668,69,1892,1789,355,1125,1790,1894,86,30,298,2208,712,1127,3,61,1129,173,1676,129,437,1584,390,187,2212,800,956,20,37,2213,328,1687,2461,961,2807,1586,718,2466,804,586,653,2216,1038,1356,2469,330,2589,1360,1801,53,2741,1361,657,2849,17,164,1244,2032,1590,1248,1367,2393,2744,2538,725,877,1920,2037,115,1922,1813,971,1053,42,1817,174,594,62,2042,442,1932,484,2140,444,538,337,55,1718,826,8,1162,147,35,1832,1835,1505,746,1386,449,750,1735,1074,2796,2778,371,548,1283,1286,1742,1746,763,1294,995,2933,346,2172,2067,96,316,2901,693,2360,2185,2186,2188,1310,1420,1423,1767,1314,2368,2093,1649,633,1875,2896,2709,1431,511,127,1019 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2937 Alcohol biosynthetic process 8 33 2.956180571119707 0.0031147467879688 Q14739,Q9UBM7,Q15392,P04062,Q13510,Q15125,Q16850,P17174 Processes and pathways GO Biological process msigdb_gobp 35,38,71,86,55,26,27,151 1206,1022,2198,212,1573,1125,2457,86,799,521,1352,151,1043,332,2472,2391,1701,2822,1709,1932,1936,55,827,35,26,1833,71,2054,2333,27,2609,2081,38 0.06384250748914849,0.17394576765407171,-0.4621081592112762,1.0129671489863166,-0.10591263929674817,0.11919997011538998,-0.6486147893595557,1.8491689704918812,0.33452611576463864,0.5401492501085412,0.007872098580347686,1.229406481355582,0.17394576765407171,0.7836800160884329,-0.6486147893595557,-0.5858198190406446,-0.16372948749216756,-1.311278575581721,-0.16372948749216756,-0.2812183777015856,-0.2812183777015856,2.5014551385438826,0.33452611576463864,3.4391717680711436,3.7024803541208557,-0.22216432068703482,2.057376685439682,-0.34089288926430916,-0.5236513396667263,3.7024803541208557,-0.7760889340064466,-0.34089288926430916,3.4162772870291325 2937 Azurophil granule membrane 10 18 2.9401756614461583 0.0032802622218766 P07602,P13473,P42785,P10253,O15260,Q6IAA8,P11279,Q99829,Q92542,O75165 Localization GO Cellular component msigdb_gocc 3,36,5,129,185,406,48,286,158,269 185,1120,269,3,129,48,36,1363,5,1143,1052,401,406,2256,158,286,2188,2616 1.101010637080487,0.11919997011538998,0.8770244243066478,5.131894866624145,1.3941514953495935,2.618889115071512,3.4162772870291325,0.007872098580347686,4.863421508907323,0.11919997011538998,0.17394576765407171,0.688050566378247,0.688050566378247,-0.4621081592112762,1.229406481355582,0.8770244243066478,-0.4011890781327106,-0.7760889340064466 2937 Abnormality of the ribs 12 55 2.9253175320258493 0.0034410490909149 Q9UM00,Q14739,P16278,Q9UBM7,P54802,Q32P28,O75844,P15586,O60826,P51798,Q9Y619,Q96L58 Drugs and Diseases Human Phenotype Ontology msigdb_hp 172,35,37,38,42,80,19,20,143,115,127,196 942,143,1663,2009,1569,2299,19,1452,575,2015,1894,1674,20,37,1352,646,961,1905,1232,2531,2929,333,2034,970,303,115,42,594,1931,2140,1156,2691,35,1269,2054,1165,2406,80,1510,2811,2251,1742,1852,346,196,1970,1403,1982,38,210,1108,172,2709,1878,127 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2937 Ectopic calcification 9 48 2.921310383996253 0.0034856237938794 Q14739,Q9UBM7,P40855,P38571,P53634,O75844,P56589,Q15125,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,38,164,17,203,19,174,26,86 1324,1326,1438,1441,1661,707,1663,2009,1890,19,212,1892,355,2458,1790,1894,86,1127,714,437,958,1684,1794,718,1360,2869,17,164,1473,2037,203,2899,2643,174,35,2051,26,2054,1731,2062,1746,2509,2186,2285,38,1319,938,2295 0.007872098580347686,0.007872098580347686,-0.04871252906513763,-0.04871252906513763,-0.16372948749216756,0.38683824468201267,-0.16372948749216756,-0.34089288926430916,-0.2812183777015856,3.926946339483657,1.0129671489863166,-0.2812183777015856,0.7361572254974664,-0.6486147893595557,-0.22216432068703482,-0.2812183777015856,1.8491689704918812,0.11919997011538998,0.38683824468201267,0.6393489264185823,0.228081190180689,-0.16372948749216756,-0.22216432068703482,0.38683824468201267,0.007872098580347686,-1.6665070292939557,3.9856208887046614,1.1870839548927827,-0.04871252906513763,-0.34089288926430916,1.057240248022844,-2.0378507439803,-0.8407704557687973,1.1442885584140452,3.4391717680711436,-0.34089288926430916,3.7024803541208557,-0.34089288926430916,-0.16372948749216756,-0.34089288926430916,-0.16372948749216756,-0.6486147893595557,-0.4011890781327106,-0.4621081592112762,3.4162772870291325,0.06384250748914849,0.2816075367943659,-0.4621081592112762 2937 Metabolism of steroids 12 40 2.920759176251376 0.0034917962597929 O75845,Q14739,Q9UBM7,Q15392,O95342,P04062,O14975,P30536,O00763,Q15125,Q16850,P37268 Processes and pathways Reactome Pathways msigdb_reactome 212,35,38,71,69,86,266,82,292,26,27,332 292,266,212,69,951,86,521,1230,2023,2634,2462,82,332,2869,2391,1367,2037,1147,1374,1709,1932,485,827,2146,35,1382,1830,26,1833,71,745,1067,2054,27,489,910,416,2356,38,2623 0.8306316454399105,0.8770244243066478,1.0129671489863166,2.057376685439682,0.228081190180689,1.8491689704918812,0.5401492501085412,0.06384250748914849,-0.34089288926430916,-0.8407704557687973,-0.6486147893595557,1.8846964555914798,0.7836800160884329,-1.6665070292939557,-0.5858198190406446,0.007872098580347686,-0.34089288926430916,0.11919997011538998,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,0.5900489466309929,0.33452611576463864,-0.4011890781327106,3.4391717680711436,0.007872098580347686,-0.22216432068703482,3.7024803541208557,-0.22216432068703482,2.057376685439682,0.38683824468201267,0.17394576765407171,-0.34089288926430916,3.7024803541208557,0.5900489466309929,0.2816075367943659,0.688050566378247,-0.5236513396667263,3.4162772870291325,-0.7760889340064466 2937 Entry into host 11 28 2.919787146097947 0.0035027053685037 P78310,Q15758,O14786,Q14108,P02786,Q8WTV0,O15118,P11279,P35613,P08195,Q9BTY2 Processes and pathways GO Biological process msigdb_gobp 188,310,97,8,41,14,75,48,145,144,52 2519,97,75,293,41,797,952,1674,144,1456,1678,48,1351,1682,1586,2470,145,659,1696,188,824,8,2145,310,14,52,2922,2290 -0.7120374352425395,1.7035577277228184,1.9547430671585866,0.8306316454399105,3.1288971739076072,0.33452611576463864,0.228081190180689,-0.16372948749216756,1.2712655154383892,-0.04871252906513763,-0.16372948749216756,2.618889115071512,0.007872098580347686,-0.16372948749216756,-0.10591263929674817,-0.6486147893595557,1.2712655154383892,0.4385452506124256,-0.16372948749216756,1.101010637080487,0.33452611576463864,4.712282471751374,-0.4011890781327106,0.8306316454399105,4.192232038011874,2.618889115071512,-3.510150275167924,-0.4621081592112762 2937 Peptide binding 14 65 2.912678606251356 0.0035834320776686 Q9UIQ6,O43813,P04439,Q15392,Q99735,Q9Y4U1,P40855,P24390,Q9Y3C6,Q8WTV0,Q9H7Z7,O14773,P42892,P01889 Functions GO Molecular function msigdb_gomf 2,66,128,71,243,248,164,74,247,14,181,24,25,120 1325,941,2519,567,24,859,2199,66,1023,2382,120,128,867,326,798,2923,1682,2461,2531,74,804,2126,1039,655,477,1470,164,25,1916,1696,1808,2132,1921,1812,663,594,1483,2397,818,2792,1491,2403,1497,1830,278,541,71,1393,14,1525,1747,844,243,1635,773,1864,181,2705,2187,1313,2707,2,1772,247,248 0.007872098580347686,0.228081190180689,-0.7120374352425395,0.48964847025575964,3.7652112572324823,0.2816075367943659,-0.4621081592112762,2.090959820673029,0.17394576765407171,-0.5858198190406446,1.434245143990909,1.3941514953495935,0.2816075367943659,0.7836800160884329,0.33452611576463864,-3.598238387349531,-0.16372948749216756,-0.6486147893595557,-0.7120374352425395,1.9892736116862897,0.33452611576463864,-0.4011890781327106,0.17394576765407171,0.4385452506124256,0.5900489466309929,-0.04871252906513763,1.1870839548927827,3.744431287238993,-0.2812183777015856,-0.16372948749216756,-0.22216432068703482,-0.4011890781327106,-0.2812183777015856,-0.22216432068703482,0.4385452506124256,0.48964847025575964,-0.04871252906513763,-0.5858198190406446,0.33452611576463864,-1.1736688722168886,-0.04871252906513763,-0.5858198190406446,-0.04871252906513763,-0.22216432068703482,0.8770244243066478,0.5401492501085412,2.057376685439682,0.007872098580347686,4.192232038011874,-0.04871252906513763,-0.16372948749216756,0.33452611576463864,0.9681807864168185,-0.10591263929674817,0.38683824468201267,-0.22216432068703482,1.1442885584140452,-0.906083163548422,-0.4011890781327106,0.06384250748914849,-0.906083163548422,5.198840694526526,-0.16372948749216756,0.9681807864168185,0.9681807864168185 2937 Nuclear outer membrane endoplasmic reticulum membrane network 83 266 2.8786626096292087 0.0039936533440463 Q99720,Q14108,Q5BJF2,O75844,Q9BQE5,Q15125,Q16850,Q14739,Q9UBM7,P07099,O43852,P35610,P67812,Q8IV08,Q15392,P24390,Q9H490,Q7Z2K6,O60725,Q96GC9,P51572,P01889,Q7Z7H5,P43307,Q8N511,P04439,Q9BUN8,P35613,Q15629,P30519,Q9UM00,P09601,Q9NX47,Q9H8Y8,Q6UWP7,O15260,Q9NQC3,Q8NFQ8,Q86UE4,O75915,O75845,P50402,Q96N66,Q99735,Q5J8M3,O60762,Q06136,Q10471,Q9Y282,Q9HD20,P61353,O94979,Q969V3,Q969M3,O14975,P49257,P49755,P51648,Q8N0U8,Q9BT22,Q14165,Q13190,Q96HY6,Q16799,Q9P2W9,Q15363,O95674,Q12907,P37268,Q9Y320,Q15041,Q9BVK6,Q92890,Q8TEM1,Q9Y678,Q07065,Q86XL3,Q6NUQ1,Q969N2,O94874,Q5VV42,Q9BU23,Q9H3N1 Localization GO Cellular component msigdb_gocc 7,8,11,19,23,26,27,35,38,39,47,53,59,63,71,74,91,98,102,118,122,120,124,121,131,128,149,145,156,153,172,173,198,197,192,185,208,223,222,213,212,217,242,243,239,228,234,235,264,262,252,250,285,284,266,272,274,275,313,316,309,306,346,340,351,339,323,336,332,379,369,418,411,409,432,401,452,449,453,436,491,501,503 565,465,1559,1325,1326,1778,2102,2447,1209,860,266,1656,2579,185,1022,2198,2581,789,1212,47,2379,1118,102,228,517,1024,1219,19,212,213,2832,436,1786,1573,2524,250,572,1342,1669,1343,951,2203,323,795,796,2457,1790,120,128,519,641,952,2116,39,1455,2526,173,2923,1229,1352,957,2632,1231,2023,1232,74,1354,804,805,1356,1909,153,806,1138,2861,1141,53,145,332,2869,1363,588,1245,121,591,1591,2391,2034,480,272,274,1808,217,1810,122,275,1052,2132,2134,1924,1147,2478,1925,2227,2720,2543,1599,729,1373,972,252,1256,1483,883,1601,2790,1705,2809,2877,2400,59,1603,1931,484,234,401,235,1264,336,1608,306,1719,1498,826,8,309,2238,2146,35,1382,2597,2852,369,2775,1613,26,339,1164,71,745,156,2054,340,27,2599,489,11,239,986,491,1511,449,1274,2339,904,192,98,124,222,547,452,1078,63,2496,2921,313,911,2498,131,679,913,914,1516,2159,2256,1519,223,2907,2163,614,2257,1850,2164,680,834,409,1288,1178,1083,837,761,411,284,453,285,1294,2423,1963,118,838,346,996,242,2067,685,7,243,2734,23,2900,2072,1533,316,501,149,1535,1406,418,1000,2428,503,91,197,2572,262,1411,208,927,198,2088,696,2187,630,2616,698,351,1311,38,1423,2763,1770,172,1012,264,379,2098,2293,2710,2802,2905,1320,2786,432,2371,2623,1558 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2937 Inorganic anion transport 6 20 2.8748859225938146 0.0040417349812349 Q9Y6M7,Q9UHG3,P08183,P51790,P30536,P51798 Processes and pathways GO Biological process msigdb_gobp 72,45,13,49,82,115 2100,1443,13,2119,394,82,1365,49,115,2135,138,1604,1261,2334,2727,685,1200,45,2292,72 -0.4011890781327106,-0.04871252906513763,4.192232038011874,-0.4011890781327106,0.688050566378247,1.8846964555914798,0.007872098580347686,2.618889115071512,1.473918375909616,-0.4011890781327106,1.3126701679029467,-0.10591263929674817,0.06384250748914849,-0.5236513396667263,-0.9720282133639213,0.4385452506124256,0.11919997011538998,2.8697220435010813,-0.4621081592112762,2.057376685439682 2937 Lipid metabolism 30 115 2.8710443693852365 0.00409118096259 P07602,Q8NCC3,P38571,Q8WVX9,Q15125,Q16850,O14975,P11498,P51648,Q14739,Q9UBM7,Q9H7Z7,P35610,O00763,Q13510,P05165,P61916,Q6UWP7,Q15392,O15118,O95674,P04062,P37268,O75845,Q96N66,Q99735,Q9UHB6,P68402,P09110,Q06136 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 3,15,17,410,26,27,266,390,275,35,38,181,53,292,55,298,62,192,71,75,323,86,332,212,242,243,377,106,357,234 465,1324,637,292,2447,266,75,2376,1022,2198,2379,1447,212,1573,1343,2203,323,795,2457,86,298,3,357,1583,1584,390,521,1461,2462,718,2466,2026,1466,2636,2861,53,332,2314,17,1244,2535,2472,810,2473,2391,2034,1367,2744,877,1051,275,2037,1701,2540,62,106,1375,1709,1932,234,2928,485,1936,55,2750,827,35,1502,1832,1724,26,1833,1614,71,2054,1068,27,2695,404,489,2339,904,192,1733,2253,2921,1081,911,679,15,2256,410,1394,837,554,242,2501,243,2734,1978,1406,2275,1002,1300,181,2081,696,630,38,377,2763,1011,1109,1558,513 0.5900489466309929,0.007872098580347686,0.4385452506124256,0.8306316454399105,-0.6486147893595557,0.8770244243066478,1.9547430671585866,-0.5858198190406446,0.17394576765407171,-0.4621081592112762,-0.5858198190406446,-0.04871252906513763,1.0129671489863166,-0.10591263929674817,0.007872098580347686,-0.4621081592112762,0.7836800160884329,0.33452611576463864,-0.6486147893595557,1.8491689704918812,0.8306316454399105,5.131894866624145,0.7361572254974664,-0.10591263929674817,-0.10591263929674817,0.688050566378247,0.5401492501085412,-0.04871252906513763,-0.6486147893595557,0.38683824468201267,-0.6486147893595557,-0.34089288926430916,-0.04871252906513763,-0.8407704557687973,-1.5941764518204824,2.589890921013961,0.7836800160884329,-0.5236513396667263,3.9856208887046614,0.06384250748914849,-0.7120374352425395,-0.6486147893595557,0.33452611576463864,-0.6486147893595557,-0.5858198190406446,-0.34089288926430916,0.007872098580347686,-1.0386067543300004,0.2816075367943659,0.17394576765407171,0.8770244243066478,-0.34089288926430916,-0.16372948749216756,-0.7120374352425395,2.157214859958303,1.59049366572062,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,0.9681807864168185,-6.020295088058086,0.5900489466309929,-0.2812183777015856,2.5014551385438826,-1.0386067543300004,0.33452611576463864,3.4391717680711436,-0.04871252906513763,-0.22216432068703482,-0.16372948749216756,3.7024803541208557,-0.22216432068703482,-0.10591263929674817,2.057376685439682,-0.34089288926430916,0.17394576765407171,3.7024803541208557,-0.906083163548422,0.688050566378247,0.5900489466309929,-0.5236513396667263,0.2816075367943659,1.101010637080487,-0.16372948749216756,-0.4621081592112762,-3.510150275167924,0.17394576765407171,0.2816075367943659,0.4385452506124256,4.0999276525600274,-0.4621081592112762,0.688050566378247,0.007872098580347686,0.33452611576463864,0.5401492501085412,0.9681807864168185,-0.6486147893595557,0.9681807864168185,-0.9720282133639213,-0.2812183777015856,0.007872098580347686,-0.4621081592112762,0.228081190180689,0.06384250748914849,1.1442885584140452,-0.34089288926430916,0.4385452506124256,0.48964847025575964,3.4162772870291325,0.7361572254974664,-1.0386067543300004,0.228081190180689,0.17394576765407171,-0.04871252906513763,0.5900489466309929 2937 Lipid catabolic process 12 73 2.864791812454422 0.0041728348228289 O95342,Q8WTV0,Q8NCC3,P06865,P38571,P35610,P50897,Q13510,P04062,P07686,P04066,P06280 Processes and pathways GO Biological process msigdb_gobp 69,14,15,16,17,53,22,55,86,61,30,31 465,292,266,2376,862,2821,948,69,1343,86,30,298,2208,31,16,61,357,1584,1034,2212,1461,2634,718,2466,2026,653,1466,2636,2469,53,2849,17,1244,2535,2472,810,2744,877,22,1051,2037,2540,106,821,2928,1936,55,1832,1724,1505,2333,1068,2695,2339,904,1733,2253,2921,1081,911,1516,15,14,763,2501,243,2356,2275,1300,2573,2088,1011,1109 0.5900489466309929,0.8306316454399105,0.8770244243066478,-0.5858198190406446,0.2816075367943659,-1.311278575581721,0.228081190180689,2.057376685439682,0.007872098580347686,1.8491689704918812,3.6169723053440874,0.8306316454399105,-0.4621081592112762,3.6169723053440874,4.024165938684547,2.1898966319486153,0.7361572254974664,-0.10591263929674817,0.17394576765407171,-0.4621081592112762,-0.04871252906513763,-0.8407704557687973,0.38683824468201267,-0.6486147893595557,-0.34089288926430916,0.4385452506124256,-0.04871252906513763,-0.8407704557687973,-0.6486147893595557,2.589890921013961,-1.5224894117754426,3.9856208887046614,0.06384250748914849,-0.7120374352425395,-0.6486147893595557,0.33452611576463864,-1.0386067543300004,0.2816075367943659,3.8063874677803375,0.17394576765407171,-0.34089288926430916,-0.7120374352425395,1.59049366572062,0.33452611576463864,-6.020295088058086,-0.2812183777015856,2.5014551385438826,-0.22216432068703482,-0.16372948749216756,-0.04871252906513763,-0.5236513396667263,0.17394576765407171,-0.906083163548422,-0.5236513396667263,0.2816075367943659,-0.16372948749216756,-0.4621081592112762,-3.510150275167924,0.17394576765407171,0.2816075367943659,-0.04871252906513763,4.0999276525600274,4.192232038011874,0.38683824468201267,-0.6486147893595557,0.9681807864168185,-0.5236513396667263,-0.4621081592112762,0.06384250748914849,-0.7120374352425395,-0.34089288926430916,0.228081190180689,0.17394576765407171 2937 Carbohydrate binding 12 40 2.855992096489024 0.0042902581370685 P49257,P10253,O75503,Q16851,P11717,O15460,Q32P28,Q14165,P35613,O60762,Q10471,Q5KU26 Functions GO Molecular function msigdb_gomf 272,129,4,168,44,200,80,309,145,228,235,28 1778,2447,200,1118,228,4,2010,1672,712,578,2117,129,799,44,1793,520,1681,2717,2681,804,805,1801,145,657,272,1920,2539,2545,1931,443,235,336,309,1265,1271,168,80,28,1736,999 -0.22216432068703482,-0.6486147893595557,1.057240248022844,0.11919997011538998,0.9681807864168185,4.878143286316388,-0.34089288926430916,-0.16372948749216756,0.38683824468201267,0.48964847025575964,-0.4011890781327106,1.3941514953495935,0.33452611576463864,2.94951498403428,-0.22216432068703482,0.5401492501085412,-0.16372948749216756,-0.9720282133639213,-0.906083163548422,0.33452611576463864,0.33452611576463864,-0.22216432068703482,1.2712655154383892,0.4385452506124256,0.8770244243066478,-0.2812183777015856,-0.7120374352425395,-0.7120374352425395,-0.2812183777015856,0.6393489264185823,0.9681807864168185,0.7836800160884329,0.8306316454399105,0.06384250748914849,0.06384250748914849,1.1870839548927827,1.919885894471246,3.681306413452911,-0.16372948749216756,0.228081190180689 2937 Endoplasmic reticulum 77 188 2.8518841638689016 0.0043460935000887 Q9H3G5,Q86UP2,Q5BJF2,Q96CN7,Q15125,Q16850,Q07020,P04843,P13674,Q9UBM7,P62081,O43852,P46782,P35610,Q8IV08,Q9P035,Q14257,Q96GC9,P46776,P46778,P51572,P23396,Q8TCT9,P43307,Q96S66,Q8N5B7,P47914,P42766,P62847,Q9NZ01,Q9BUN8,O60826,Q9P2E9,P67809,O43169,Q9UM00,P20042,P04844,P30533,P62841,Q86SZ2,Q6UWP7,O15260,Q9NQC3,O15460,Q86UE4,O75915,O75845,P50402,Q99735,Q15293,P62750,Q969M3,P49257,P51648,Q8N0U8,Q9BT22,Q9NVZ3,P46779,Q96HY6,Q16799,Q96KA5,Q9P265,Q9P2W9,O95674,O96005,P37268,Q15041,Q96A57,Q9Y3U8,P62277,Q86XL3,P46777,O94874,Q9H3N1,P18124,P61254 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 1,547,11,555,26,27,537,519,520,38,533,47,531,53,63,630,79,118,589,590,122,585,680,121,685,679,134,137,139,696,149,143,698,154,150,172,647,641,655,664,194,192,185,208,200,222,213,212,217,243,237,233,284,272,275,313,316,320,302,346,340,347,350,351,323,324,332,369,414,428,399,452,440,436,503,475,481 1325,860,2579,185,1022,200,150,2581,789,1212,47,143,2582,1024,212,213,436,1573,1342,1669,1343,323,324,2457,519,641,2016,2584,797,1674,2117,1792,2119,868,520,956,1229,1683,2632,475,2308,647,2121,802,2531,585,964,1907,804,805,1797,1909,655,1587,1141,53,809,332,1363,137,121,589,440,590,302,531,134,2034,1694,272,217,970,1699,1810,122,275,2642,2720,2479,1600,481,973,1483,883,533,816,2644,2040,817,1705,399,2230,233,1058,1059,664,139,2136,2645,1486,665,732,1819,1820,154,819,974,735,537,1264,1608,1063,2690,978,826,79,2238,1265,1382,369,1613,26,237,901,2054,340,27,1729,11,1274,904,1275,1388,192,194,222,547,452,63,2921,313,679,913,1518,2256,2907,1850,680,759,1083,284,1294,414,2423,555,1963,1853,118,346,347,996,685,243,2734,2071,1533,316,149,1,503,2572,208,1866,320,696,630,2616,350,698,351,38,1991,782,1423,172,428,856,2623 0.007872098580347686,0.2816075367943659,-0.7760889340064466,1.101010637080487,0.17394576765407171,1.057240248022844,1.229406481355582,-0.7760889340064466,0.33452611576463864,0.06384250748914849,2.760432113941949,1.2712655154383892,-0.7760889340064466,0.17394576765407171,1.0129671489863166,1.0129671489863166,0.6393489264185823,-0.10591263929674817,0.007872098580347686,-0.16372948749216756,0.007872098580347686,0.7836800160884329,0.7836800160884329,-0.6486147893595557,0.5401492501085412,0.4385452506124256,-0.34089288926430916,-0.7760889340064466,0.33452611576463864,-0.16372948749216756,-0.4011890781327106,-0.22216432068703482,-0.4011890781327106,0.2816075367943659,0.5401492501085412,0.228081190180689,0.06384250748914849,-0.16372948749216756,-0.8407704557687973,0.5900489466309929,-0.5236513396667263,0.4385452506124256,-0.4011890781327106,0.33452611576463864,-0.7120374352425395,0.48964847025575964,0.228081190180689,-0.2812183777015856,0.33452611576463864,0.33452611576463864,-0.22216432068703482,-0.2812183777015856,0.4385452506124256,-0.10591263929674817,0.11919997011538998,2.589890921013961,0.33452611576463864,0.7836800160884329,0.007872098580347686,1.3126701679029467,1.434245143990909,0.48964847025575964,0.6393489264185823,0.48964847025575964,0.8306316454399105,0.5401492501085412,1.3536292924938709,-0.34089288926430916,-0.16372948749216756,0.8770244243066478,1.0129671489863166,0.228081190180689,-0.16372948749216756,-0.22216432068703482,1.434245143990909,0.8770244243066478,-0.8407704557687973,-0.9720282133639213,-0.6486147893595557,-0.10591263929674817,0.5900489466309929,0.228081190180689,-0.04871252906513763,0.2816075367943659,0.5401492501085412,0.33452611576463864,-0.8407704557687973,-0.34089288926430916,0.33452611576463864,-0.16372948749216756,0.688050566378247,-0.4621081592112762,0.9681807864168185,0.17394576765407171,0.17394576765407171,0.4385452506124256,1.3126701679029467,-0.4011890781327106,-0.8407704557687973,-0.04871252906513763,0.4385452506124256,0.38683824468201267,-0.22216432068703482,-0.22216432068703482,1.229406481355582,0.33452611576463864,0.228081190180689,0.38683824468201267,0.5401492501085412,0.06384250748914849,-0.10591263929674817,0.17394576765407171,-0.906083163548422,0.228081190180689,0.33452611576463864,1.919885894471246,-0.4621081592112762,0.06384250748914849,0.007872098580347686,0.7361572254974664,-0.10591263929674817,3.7024803541208557,0.9681807864168185,0.2816075367943659,-0.34089288926430916,0.7836800160884329,3.7024803541208557,-0.16372948749216756,4.2819961355673675,0.06384250748914849,0.2816075367943659,0.06384250748914849,0.007872098580347686,1.101010637080487,1.101010637080487,1.0129671489863166,0.5401492501085412,0.6393489264185823,2.157214859958303,-3.510150275167924,0.8306316454399105,0.4385452506124256,0.2816075367943659,-0.04871252906513763,-0.4621081592112762,-2.268447955689181,-0.22216432068703482,0.4385452506124256,0.38683824468201267,0.17394576765407171,0.8770244243066478,0.06384250748914849,0.688050566378247,-0.5858198190406446,0.5401492501085412,-0.2812183777015856,-0.22216432068703482,1.473918375909616,0.7836800160884329,0.7836800160884329,0.228081190180689,0.4385452506124256,0.9681807864168185,-0.9720282133639213,-0.34089288926430916,-0.04871252906513763,0.8306316454399105,1.2712655154383892,5.830215713580066,0.5900489466309929,-0.7120374352425395,1.057240248022844,-0.22216432068703482,0.8306316454399105,0.4385452506124256,0.48964847025575964,-0.7760889340064466,0.7836800160884329,0.4385452506124256,0.7836800160884329,3.4162772870291325,-0.2812183777015856,0.38683824468201267,0.007872098580347686,1.1870839548927827,0.688050566378247,0.33452611576463864,-0.7760889340064466 2937 Metallopeptidase activity 9 40 2.848585763080931 0.0043914015728581 Q9UIQ6,O75976,Q7Z2K6,P12955,P02786,Q969V3,O75844,Q5JRX3,P42892 Functions GO Molecular function msigdb_gomf 2,34,98,187,41,285,19,157,25 1562,466,468,790,2627,19,34,2013,41,1583,187,1682,1233,1796,1361,25,2476,813,2395,663,538,157,674,1623,98,553,285,2817,496,1530,2733,286,773,1983,2762,1642,627,2187,2,1016 -0.10591263929674817,0.5900489466309929,0.5900489466309929,0.33452611576463864,-0.8407704557687973,3.926946339483657,3.4391717680711436,-0.34089288926430916,3.1288971739076072,-0.10591263929674817,1.101010637080487,-0.16372948749216756,0.06384250748914849,-0.22216432068703482,0.007872098580347686,3.744431287238993,-0.6486147893595557,0.33452611576463864,-0.5858198190406446,0.4385452506124256,0.5401492501085412,1.229406481355582,0.4385452506124256,-0.10591263929674817,1.7035577277228184,0.5401492501085412,0.8770244243066478,-1.2421547136861633,0.5900489466309929,-0.04871252906513763,-0.9720282133639213,0.8770244243066478,0.38683824468201267,-0.2812183777015856,-1.0386067543300004,-0.10591263929674817,0.48964847025575964,-0.4011890781327106,5.198840694526526,0.228081190180689 2937 Glycosaminoglycan metabolism 6 12 2.843371634163247 0.0044638986780525 P16278,P54802,O43505,P06865,P15586,P07686 Processes and pathways Reactome Pathways msigdb_reactome 37,42,76,16,20,61 2448,76,16,61,20,37,42,344,2161,614,196,1107 -0.6486147893595557,1.9547430671585866,4.024165938684547,2.1898966319486153,3.887244197186541,3.4162772870291325,3.078582353860239,0.7836800160884329,-0.4011890781327106,0.48964847025575964,1.101010637080487,0.17394576765407171 2937 Disproportionate short stature 9 24 2.841029337718681 0.0044968175325261 Q96HY6,Q14739,P16278,Q9UBM7,Q15392,Q7LGA3,Q9UBN7,Q32P28,Q15125 Drugs and Diseases Human Phenotype Ontology msigdb_hp 346,35,37,38,71,344,210,80,26 1324,1438,1663,2299,714,37,2531,529,588,1591,337,35,983,26,71,80,1510,344,1852,346,2856,38,210,1108 0.007872098580347686,-0.04871252906513763,-0.16372948749216756,-0.5236513396667263,0.38683824468201267,3.4162772870291325,-0.7120374352425395,0.5401492501085412,0.48964847025575964,-0.10591263929674817,0.7836800160884329,3.4391717680711436,0.228081190180689,3.7024803541208557,2.057376685439682,1.919885894471246,-0.04871252906513763,0.7836800160884329,-0.22216432068703482,0.7836800160884329,-1.5224894117754426,3.4162772870291325,1.057240248022844,0.17394576765407171 2937 Basal part of cell 16 40 2.837740139392717 0.0045434155561261 Q99808,P53985,P78310,P42785,Q15758,P11166,Q9Y6M7,Q07157,P55011,P02786,O95342,Q14254,P35613,P08195,P26038,O75122 Localization GO Cellular component msigdb_gocc 99,276,188,5,310,437,72,255,138,41,69,368,145,144,270,268 1114,2768,1329,268,1571,865,69,41,2680,1895,2304,144,867,437,1033,1682,439,2911,1686,270,807,1140,1360,145,5,276,1369,138,881,188,255,2872,1827,1500,368,310,1401,99,2185,72 0.11919997011538998,-1.1058199287517425,0.007872098580347686,0.8770244243066478,-0.10591263929674817,0.2816075367943659,2.057376685439682,3.1288971739076072,-0.906083163548422,-0.2812183777015856,-0.5236513396667263,1.2712655154383892,0.2816075367943659,0.6393489264185823,0.17394576765407171,-0.16372948749216756,0.6393489264185823,-2.425443155290095,-0.16372948749216756,0.8770244243066478,0.33452611576463864,0.11919997011538998,0.007872098580347686,1.2712655154383892,4.863421508907323,0.8770244243066478,0.007872098580347686,1.3126701679029467,0.2816075367943659,1.101010637080487,0.9228702829555585,-1.6665070292939557,-0.22216432068703482,-0.04871252906513763,0.7361572254974664,0.8306316454399105,0.007872098580347686,1.7035577277228184,-0.4011890781327106,2.057376685439682 2937 Vesicle lumen 15 109 2.836899203839456 0.0045553990767135 P16278,P42025,P68402,Q9H7Z7,Q08380,P15586,Q9BTY2,Q92820,P15289,P61916,P10619,Q8NBX0,P07686,P04066,P06280 Localization GO Cellular component msigdb_gocc 37,165,106,181,18,20,52,54,95,62,58,60,61,30,31 940,1561,466,1882,515,1443,705,948,2383,2457,1221,30,1672,1576,31,712,578,2304,1580,61,642,713,867,357,954,2209,58,1457,2528,2529,473,1227,1680,2021,800,1899,2884,95,20,37,2717,958,393,1685,1134,2588,2467,2125,872,1466,2218,1801,1242,1470,165,660,812,1479,813,1701,203,2478,1703,62,595,106,1151,1489,18,2236,1063,1064,2690,668,1160,669,1830,1268,2873,281,2777,1172,908,2926,1283,1518,60,54,1963,619,1749,843,2608,686,2351,2072,52,2354,1098,181,1100,1413,505,2829,1551,1993,2092,1772,1013 0.228081190180689,-0.10591263929674817,0.5900489466309929,-0.2812183777015856,0.5401492501085412,-0.04871252906513763,0.38683824468201267,0.228081190180689,-0.5858198190406446,-0.6486147893595557,0.06384250748914849,3.6169723053440874,-0.16372948749216756,-0.10591263929674817,3.6169723053440874,0.38683824468201267,0.48964847025575964,-0.5236513396667263,-0.10591263929674817,2.1898966319486153,0.4385452506124256,0.38683824468201267,0.2816075367943659,0.7361572254974664,0.228081190180689,-0.4621081592112762,2.3177619175977977,-0.04871252906513763,-0.7120374352425395,-0.7120374352425395,0.5900489466309929,0.06384250748914849,-0.16372948749216756,-0.34089288926430916,0.33452611576463864,-0.2812183777015856,-1.8873708060077286,1.7404982072045598,3.887244197186541,3.4162772870291325,-0.9720282133639213,0.228081190180689,0.688050566378247,-0.16372948749216756,0.11919997011538998,-0.7760889340064466,-0.6486147893595557,-0.4011890781327106,0.2816075367943659,-0.04871252906513763,-0.4621081592112762,-0.22216432068703482,0.06384250748914849,-0.04871252906513763,1.1870839548927827,0.4385452506124256,0.33452611576463864,-0.04871252906513763,0.33452611576463864,-0.16372948749216756,1.057240248022844,-0.6486147893595557,-0.16372948749216756,2.157214859958303,0.48964847025575964,1.59049366572062,0.11919997011538998,-0.04871252906513763,3.9661781891098036,-0.4621081592112762,0.17394576765407171,0.17394576765407171,-0.906083163548422,0.4385452506124256,0.11919997011538998,0.4385452506124256,-0.22216432068703482,0.06384250748914849,-1.6665070292939557,0.8770244243066478,-1.1058199287517425,0.11919997011538998,0.2816075367943659,-3.9572906345869274,0.06384250748914849,-0.04871252906513763,2.222287625540094,2.5311775269119203,-0.2812183777015856,0.48964847025575964,-0.16372948749216756,0.33452611576463864,-0.7760889340064466,0.4385452506124256,-0.5236513396667263,-0.34089288926430916,2.618889115071512,-0.5236513396667263,0.17394576765407171,1.1442885584140452,0.17394576765407171,0.007872098580347686,0.5900489466309929,-1.311278575581721,-0.04871252906513763,-0.2812183777015856,-0.34089288926430916,-0.16372948749216756,0.228081190180689 2937 Golgi apparatus subcompartment 28 73 2.8319183029951165 0.0046269668925764 P04439,Q969E2,Q96A57,O14828,Q8WWQ0,Q969M3,Q9Y296,Q92538,P61006,O43795,Q10713,P20645,O75122,Q5VYK3,P11717,Q96L58,Q86SZ2,P50570,P98194,Q15363,Q9BTU6,Q4J6C6,P09496,P04062,Q10471,Q8TBA6,O15127,P51572 Localization GO Cellular component msigdb_gocc 128,135,414,249,551,284,425,283,395,385,538,152,268,405,44,196,194,303,204,339,500,85,326,86,235,373,113,122 1563,249,113,2105,385,1118,1335,268,2010,86,128,326,798,2119,44,152,1905,2023,1796,1243,1247,303,1919,122,1052,532,2541,395,1373,972,204,1062,1263,2721,235,823,538,2653,982,1725,339,1271,85,2337,405,2491,194,373,1288,551,283,135,284,414,196,2173,2759,500,999,1408,1638,2430,2434,2280,2088,933,1768,1770,935,425,2576,2001,2623 -0.10591263929674817,0.9228702829555585,1.473918375909616,-0.4011890781327106,0.688050566378247,0.11919997011538998,0.007872098580347686,0.8770244243066478,-0.34089288926430916,1.8491689704918812,1.3941514953495935,0.7836800160884329,0.33452611576463864,-0.4011890781327106,2.94951498403428,1.229406481355582,-0.2812183777015856,-0.34089288926430916,-0.22216432068703482,0.06384250748914849,0.06384250748914849,0.8306316454399105,-0.2812183777015856,1.434245143990909,0.17394576765407171,0.5401492501085412,-0.7120374352425395,0.688050566378247,0.007872098580347686,0.228081190180689,1.057240248022844,0.17394576765407171,0.06384250748914849,-0.9720282133639213,0.9681807864168185,0.33452611576463864,0.5401492501085412,-0.8407704557687973,0.228081190180689,-0.16372948749216756,0.7836800160884329,0.06384250748914849,1.8846964555914798,-0.5236513396667263,0.688050566378247,-0.6486147893595557,1.101010637080487,0.7361572254974664,0.06384250748914849,0.5401492501085412,0.8770244243066478,1.3536292924938709,0.8770244243066478,0.688050566378247,1.101010637080487,-0.4011890781327106,-1.0386067543300004,0.5900489466309929,0.228081190180689,0.007872098580347686,-0.10591263929674817,-0.5858198190406446,-0.5858198190406446,-0.4621081592112762,-0.34089288926430916,0.2816075367943659,-0.16372948749216756,-0.16372948749216756,0.2816075367943659,0.688050566378247,-0.7120374352425395,-0.2812183777015856,-0.7760889340064466 2937 Predicted secreted proteins 12 42 2.8290241347302096 0.0046690177796644 Q9HB40,Q9UMX5,P78310,O94813,O14786,Q02818,P02786,Q15165,Q08380,P80303,Q9BTY2,P61916 Functions Protein Atlas Protein class protein_atlas_protein_class 0,65,188,68,97,40,41,110,18,50,52,62 97,1118,294,2299,68,1574,41,2680,578,2304,954,800,1682,2531,202,530,2477,1924,2642,62,188,50,2930,40,444,18,1935,2482,110,372,548,2063,1523,2265,1186,52,1535,1983,0,2187,65,2802 1.7035577277228184,0.11919997011538998,0.8306316454399105,-0.5236513396667263,2.057376685439682,-0.10591263929674817,3.1288971739076072,-0.906083163548422,0.48964847025575964,-0.5236513396667263,0.228081190180689,0.33452611576463864,-0.16372948749216756,-0.7120374352425395,1.057240248022844,0.5401492501085412,-0.6486147893595557,-0.2812183777015856,-0.8407704557687973,2.157214859958303,1.101010637080487,2.618889115071512,-6.2325523544671535,3.17849140779286,0.6393489264185823,3.9661781891098036,-0.2812183777015856,-0.6486147893595557,1.5131791067781917,0.7361572254974664,0.5401492501085412,-0.34089288926430916,-0.04871252906513763,-0.4621081592112762,0.11919997011538998,2.618889115071512,-0.04871252906513763,-0.2812183777015856,5.893957451831641,-0.4011890781327106,2.124237547972303,-1.1736688722168886 2937 Endoplasmic reticulum golgi intermediate compartment membrane 13 19 2.8285006408425084 0.0046766607457462 P49257,Q8N511,P49755,O15260,P24390,Q15363,P53634,Q13190,Q12907,O15498,Q96GC9,P51572,Q9Y282 Localization GO Cellular component msigdb_gocc 272,131,274,185,74,339,203,306,336,227,118,122,264 185,227,1219,572,74,804,272,274,122,203,2721,336,306,339,131,118,418,264,2293 1.101010637080487,0.9681807864168185,0.06384250748914849,0.48964847025575964,1.9892736116862897,0.33452611576463864,0.8770244243066478,0.8770244243066478,1.434245143990909,1.057240248022844,-0.9720282133639213,0.7836800160884329,0.8306316454399105,0.7836800160884329,1.3941514953495935,1.473918375909616,0.688050566378247,0.9228702829555585,-0.4621081592112762 2937 golgi 17 55 2.819099967462781 0.0048158517121308 P49755,Q9UM00,Q969E2,Q8IXU6,O94979,Q8N6T3,Q92538,Q969M3,O15127,Q9Y487,Q13190,Q9Y3E0,P09496,Q5VW38,O15258,Q9H8Y8,O75122 Localization OpenCell Localization opencell_localization 274,172,135,6,250,345,283,284,113,430,306,226,326,88,322,197,268 2102,2447,1437,2373,113,322,268,250,1669,326,798,959,2022,2023,1141,967,1243,274,532,1924,1147,1055,1925,1373,1601,1059,1062,2721,306,745,984,88,1169,1074,6,345,1288,283,135,284,1086,2074,2428,197,1866,927,2616,1311,172,634,226,2444,430,432,2623 -0.4011890781327106,-0.6486147893595557,-0.04871252906513763,-0.5858198190406446,1.473918375909616,0.7836800160884329,0.8770244243066478,0.9228702829555585,-0.16372948749216756,0.7836800160884329,0.33452611576463864,0.228081190180689,-0.34089288926430916,-0.34089288926430916,0.11919997011538998,0.228081190180689,0.06384250748914849,0.8770244243066478,0.5401492501085412,-0.2812183777015856,0.11919997011538998,0.17394576765407171,-0.2812183777015856,0.007872098580347686,-0.10591263929674817,0.17394576765407171,0.17394576765407171,-0.9720282133639213,0.8306316454399105,0.38683824468201267,0.228081190180689,1.8491689704918812,0.11919997011538998,0.17394576765407171,4.8486302687541105,0.7836800160884329,0.06384250748914849,0.8770244243066478,1.3536292924938709,0.8770244243066478,0.17394576765407171,-0.34089288926430916,-0.5858198190406446,1.101010637080487,-0.22216432068703482,0.2816075367943659,-0.7760889340064466,0.06384250748914849,1.1870839548927827,0.48964847025575964,1.0129671489863166,-0.5858198190406446,0.688050566378247,0.688050566378247,-0.7760889340064466 2937 Trans golgi network vesicle budding 7 29 2.8105747617038044 0.0049453098224416 O75976,P02786,P11717,Q92538,P15586,P20645,P50570 Processes and pathways Reactome Pathways msigdb_reactome 34,41,44,283,20,152,303 2578,1020,1563,2373,2105,570,34,41,326,798,1457,44,20,152,303,1143,1052,1055,1062,823,1497,896,982,1518,283,682,1408,1002,2001 -0.7760889340064466,0.17394576765407171,-0.10591263929674817,-0.5858198190406446,-0.4011890781327106,0.48964847025575964,3.4391717680711436,3.1288971739076072,0.7836800160884329,0.33452611576463864,-0.04871252906513763,2.94951498403428,3.887244197186541,1.229406481355582,0.8306316454399105,0.11919997011538998,0.17394576765407171,0.17394576765407171,0.17394576765407171,0.33452611576463864,-0.04871252906513763,0.2816075367943659,0.228081190180689,-0.04871252906513763,0.8770244243066478,0.4385452506124256,0.007872098580347686,0.228081190180689,-0.2812183777015856 2937 Phospholipid binding 16 75 2.807428128594924 0.0049938822111794 P35080,Q15286,P07602,Q96AC1,Q14108,Q9UNH7,Q92538,Q8WTV0,Q8NCC3,Q99829,P50897,O60493,O14773,Q9H490,O43795,P46940 Functions GO Molecular function msigdb_gomf 331,256,3,241,8,352,283,14,15,286,22,293,24,91,385,215 565,1207,1563,24,1439,789,385,1661,293,570,1120,2680,2304,3,2385,1896,954,1457,1033,1231,523,394,2023,2532,1798,331,1471,1365,2390,215,480,22,1480,532,886,596,1153,445,1497,742,1158,8,1723,256,2601,1624,1954,1513,15,2555,14,283,761,241,286,1858,1533,1407,1000,91,2430,2359,2188,1009,1768,2090,1554,702,2708,352,1428,787,2919,2711,2001 0.48964847025575964,0.06384250748914849,-0.10591263929674817,3.7652112572324823,-0.04871252906513763,0.33452611576463864,0.688050566378247,-0.16372948749216756,0.8306316454399105,0.48964847025575964,0.11919997011538998,-0.906083163548422,-0.5236513396667263,5.131894866624145,-0.5858198190406446,-0.2812183777015856,0.228081190180689,-0.04871252906513763,0.17394576765407171,0.06384250748914849,0.5401492501085412,0.688050566378247,-0.34089288926430916,-0.7120374352425395,-0.22216432068703482,0.7836800160884329,-0.04871252906513763,0.007872098580347686,-0.5858198190406446,1.0129671489863166,0.5900489466309929,3.8063874677803375,-0.04871252906513763,0.5401492501085412,0.2816075367943659,0.48964847025575964,0.11919997011538998,0.6393489264185823,-0.04871252906513763,0.38683824468201267,0.11919997011538998,4.712282471751374,-0.16372948749216756,0.9228702829555585,-0.7760889340064466,-0.10591263929674817,-0.2812183777015856,-0.04871252906513763,4.0999276525600274,-0.7120374352425395,4.192232038011874,0.8770244243066478,0.38683824468201267,0.9681807864168185,0.8770244243066478,-0.22216432068703482,-0.04871252906513763,0.007872098580347686,0.228081190180689,1.8491689704918812,-0.5858198190406446,-0.5236513396667263,-0.4011890781327106,0.228081190180689,-0.16372948749216756,-0.34089288926430916,-0.04871252906513763,0.4385452506124256,-0.906083163548422,0.7836800160884329,0.007872098580347686,0.38683824468201267,-2.9956170913795845,-0.906083163548422,-0.2812183777015856 2937 Kyphosis 27 144 2.802866350187569 0.0050650654167598 Q9BTV4,Q14108,P55011,O75844,O60826,Q15125,Q5KU26,P04066,P51648,Q14739,P16278,Q9UBM7,Q9BT22,Q9NR77,Q96L58,P52788,Q6NW34,Q7LGA3,Q32P28,O75175,P04062,P50402,Q96AY3,Q9H0B6,P41227,Q9BZI7,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 258,8,138,19,143,26,28,30,275,35,37,38,316,57,196,70,343,344,80,201,86,217,105,107,231,125,120 939,1561,1563,1778,942,1331,2107,2626,143,201,1663,1664,1783,19,1573,1667,1668,1452,2383,1027,575,2679,2015,1790,120,1894,86,30,1347,1454,1674,327,714,37,1035,1684,646,1794,961,1905,523,1688,1232,2531,963,1463,1038,2684,967,2885,231,875,1590,2034,217,2887,1249,275,2640,70,1922,2134,1815,138,1598,2396,2745,1150,666,596,2594,1931,1932,484,2140,975,1935,1154,1156,598,980,8,2240,1829,35,983,2775,1503,26,899,2054,2406,80,28,1948,1510,343,2058,2251,2699,344,1172,2813,1174,678,2160,2161,1519,834,1178,2500,105,196,1968,1089,1970,1753,1091,687,316,258,125,107,2428,1982,846,1411,57,851,1417,1310,38,507,1108,2287,509,1773,425,1875,2896,430,2802,1999,2711 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2937 Vascular skin abnormality 21 110 2.7931564742881765 0.0052196436485205 Q14108,Q99829,O75844,Q15125,P04066,P06280,P49257,Q14739,P16278,Q9UBM7,P10619,Q96L58,P12955,P98194,Q6NUK1,P04062,P51798,O60762,Q06136,P01889,Q9H1A4 Drugs and Diseases Human Phenotype Ontology msigdb_hp 8,286,19,26,30,31,272,35,37,38,58,196,187,204,220,86,115,228,234,120,260 939,942,1332,1334,1118,228,707,1119,1446,1890,19,388,1892,2458,120,1894,86,30,31,1127,2459,58,714,2211,187,1585,2911,37,1132,1684,1794,1905,523,1688,802,1586,2463,804,1038,872,2637,1468,1360,587,967,657,2869,2127,2471,2885,1590,2034,272,1367,725,1593,275,115,2640,2924,1147,2225,1815,2643,204,2594,1931,1932,2140,234,2749,1607,1712,1494,337,2691,8,1501,1829,35,1723,26,1163,1269,2054,1384,2337,2811,220,2339,2058,2753,2161,2700,1746,411,453,1184,196,1970,286,2569,260,2186,38,632,2709,1319,430,2905 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2937 Golgi apparatus 76 262 2.7901114542106966 0.00526899000586 Q9BTV4,Q9BVK6,Q96SU4,O75503,P04439,Q969E2,Q92896,Q14108,O14828,Q96A57,Q93050,Q92538,Q969M3,Q9Y296,Q6ZRP7,P35613,Q9Y4A5,Q9Y678,P50897,O14773,Q92542,P61006,P20645,O75122,P06280,P49257,P49755,Q9UM00,P16278,Q02818,Q14004,P11717,Q9H7Z7,O43852,Q9Y266,P51790,P80303,Q13190,Q9UQB8,Q9H8Y8,Q96L58,Q8IV08,Q86SZ2,P50570,Q16799,Q15392,O15260,O95342,Q7LGA3,P24390,Q99805,Q8N6T3,O43505,O15118,P98194,Q9P2W9,Q15363,P53634,Q9Y3E0,Q4J6C6,Q12907,P09496,Q5VW38,O15258,P04062,Q10471,Q8TBA6,Q14247,O15127,O15498,P07305,P51572,Q9Y282,P01889,Q7Z7H5,P50851 Localization GO Cellular component msigdb_gocc 258,418,416,4,128,135,412,8,249,414,413,283,284,425,148,145,431,432,22,24,158,395,152,268,31,272,274,172,37,40,166,44,181,47,184,49,50,306,56,197,196,63,194,303,340,71,185,69,344,74,207,345,76,75,204,351,339,203,226,85,336,326,88,322,86,235,373,367,113,227,356,122,264,120,124,362 2518,1020,1207,1326,1563,2102,1115,2447,1781,24,249,2373,2579,75,113,322,185,227,1659,1333,76,2377,2105,385,2108,47,1118,1218,1335,268,1219,4,1339,2010,572,1342,1669,69,640,2203,794,1670,2806,796,1790,120,86,128,1895,31,356,2526,326,798,2119,2923,437,44,37,1901,1460,959,152,1905,1135,2023,1586,74,2929,2311,871,804,872,1796,655,526,1467,1141,145,1045,2898,1142,1243,588,875,1247,1591,480,272,1367,274,812,303,362,22,1051,1919,122,49,1052,2132,1146,532,2134,1924,203,2541,2543,1599,395,1373,972,1601,1059,1708,50,885,204,1062,2594,40,484,1263,2721,235,823,538,1935,336,2872,306,1497,1158,2050,1609,2653,166,8,367,1265,982,1723,2775,1725,339,1164,71,745,1945,1271,340,85,2337,88,405,2491,1274,1169,2795,1387,1276,148,2251,344,1074,1625,1172,124,1736,194,908,1279,63,1081,2498,345,2161,2256,1519,614,373,1741,834,1392,2889,1288,551,283,158,2934,682,412,1292,413,135,2265,284,1086,414,196,685,416,2173,207,2759,2610,500,258,1535,418,2798,999,2074,1408,1638,1760,1002,1538,2430,181,197,2434,1303,2781,1411,2280,1866,927,506,2088,2882,2616,351,1311,1107,933,1551,1768,1770,784,172,1316,935,1647,1202,56,184,264,425,2442,1014,2875,634,2576,2293,226,431,2001,432,2623,1558,636 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2937 Abnormal tissue metabolite concentration 6 13 2.7848816323622136 0.0053547266539428 P07602,P40855,P06865,P07686,P15289,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,164,16,61,95,31 1443,355,31,16,3,61,95,164,2037,174,2796,2188,2094 -0.04871252906513763,0.7361572254974664,3.6169723053440874,4.024165938684547,5.131894866624145,2.1898966319486153,1.7404982072045598,1.1870839548927827,-0.34089288926430916,1.1442885584140452,-1.1736688722168886,-0.4011890781327106,-0.34089288926430916 2937 Regulation of response to external stimulus 32 116 2.7704870724216 0.0055972522064311 P04439,Q92890,P55011,O15164,O75844,Q9H4A3,O75122,O43657,Q9Y5A9,Q9NX58,P11279,P80303,Q9UII4,Q9UMX5,O94813,Q9UNH7,O94874,Q07021,P26583,Q13177,P53634,Q15942,Q96QK1,Q96PK6,P04062,P39019,Q99496,O14786,Q96BN8,Q99735,Q9Y4E8,P01889 Processes and pathways GO Biological process msigdb_gobp 128,411,138,10,19,160,268,33,321,182,48,50,199,65,68,352,436,444,202,446,203,84,498,497,86,333,96,97,374,243,380,120 1326,97,2003,1329,10,1332,33,2105,1119,268,1569,2010,19,68,2382,436,1667,2455,120,86,2680,128,713,867,954,48,1227,1680,800,2632,1461,1905,524,2312,202,871,804,586,872,2388,525,1239,1140,333,1473,1589,2685,1052,203,1250,138,2643,881,728,2228,2232,2893,50,2401,1929,2594,1932,2792,2140,444,2234,1378,446,1718,1941,896,2051,899,2330,1067,84,1166,2873,604,746,2334,2854,2060,677,911,549,2163,1524,2663,411,374,918,497,498,1089,96,2609,243,1404,1757,160,505,1006,2185,182,2187,1196,1547,2845,199,2089,65,352,1319,380,321 0.007872098580347686,1.7035577277228184,-0.34089288926430916,0.007872098580347686,4.369343782243772,0.007872098580347686,3.4619133058097864,-0.4011890781327106,0.11919997011538998,0.8770244243066478,-0.10591263929674817,-0.34089288926430916,3.926946339483657,2.057376685439682,-0.5858198190406446,0.6393489264185823,-0.16372948749216756,-0.6486147893595557,1.434245143990909,1.8491689704918812,-0.906083163548422,1.3941514953495935,0.38683824468201267,0.2816075367943659,0.228081190180689,2.618889115071512,0.06384250748914849,-0.16372948749216756,0.33452611576463864,-0.8407704557687973,-0.04871252906513763,-0.2812183777015856,0.5401492501085412,-0.5236513396667263,1.057240248022844,0.2816075367943659,0.33452611576463864,0.48964847025575964,0.2816075367943659,-0.5858198190406446,0.5401492501085412,0.06384250748914849,0.11919997011538998,0.7836800160884329,-0.04871252906513763,-0.10591263929674817,-0.906083163548422,0.17394576765407171,1.057240248022844,0.06384250748914849,1.3126701679029467,-0.8407704557687973,0.2816075367943659,0.38683824468201267,-0.4621081592112762,-0.4621081592112762,-1.96228632337628,2.618889115071512,-0.5858198190406446,-0.2812183777015856,-0.7760889340064466,-0.2812183777015856,-1.1736688722168886,-0.4011890781327106,0.6393489264185823,-0.4621081592112762,0.007872098580347686,0.6393489264185823,-0.16372948749216756,-0.2812183777015856,0.2816075367943659,-0.34089288926430916,0.2816075367943659,-0.5236513396667263,0.17394576765407171,1.8846964555914798,0.11919997011538998,-1.6665070292939557,0.48964847025575964,0.38683824468201267,-0.5236513396667263,-1.5224894117754426,-0.34089288926430916,0.4385452506124256,0.2816075367943659,0.5401492501085412,-0.4011890781327106,-0.04871252906513763,-0.8407704557687973,0.688050566378247,0.7361572254974664,0.2816075367943659,0.5900489466309929,0.5900489466309929,0.17394576765407171,1.7404982072045598,-0.7760889340064466,0.9681807864168185,0.007872098580347686,-0.16372948749216756,1.229406481355582,0.5900489466309929,0.228081190180689,-0.4011890781327106,1.1442885584140452,-0.4011890781327106,0.11919997011538998,-0.04871252906513763,-1.451444818165324,1.101010637080487,-0.34089288926430916,2.124237547972303,0.7836800160884329,0.06384250748914849,0.7361572254974664,0.8306316454399105 2937 Abnormality of the peripheral nervous system 16 96 2.7680300729034624 0.0056396251476646 P07602,Q9UBM7,Q99720,Q9Y619,P20700,Q9NQZ5,P41227,Q9NSV4,Q9H4A3,P42892,Q15125,P04062,Q9NR77,P07686,P15289,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,38,7,127,133,246,231,288,160,25,26,86,57,61,95,31 942,1022,2198,1332,1443,1334,2713,1661,269,2832,1668,1787,575,1894,86,31,3,61,95,2681,1794,133,802,2029,1241,2898,2314,231,1693,25,1589,1590,2222,1695,303,1051,1249,2037,1147,971,2478,2396,2745,1931,443,736,1490,538,2750,826,669,1829,1832,2824,26,1269,2697,2698,2058,1276,2699,1075,2844,911,1515,913,2164,2700,1746,411,683,1967,1968,498,997,2609,2173,7,1191,160,246,57,2669,288,1766,424,2188,2285,1010,38,1424,1431,2622,2905,127,513 0.228081190180689,0.17394576765407171,-0.4621081592112762,0.007872098580347686,-0.04871252906513763,0.007872098580347686,-0.9720282133639213,-0.16372948749216756,0.8770244243066478,-1.3810415738737563,-0.16372948749216756,-0.22216432068703482,0.48964847025575964,-0.2812183777015856,1.8491689704918812,3.6169723053440874,5.131894866624145,2.1898966319486153,1.7404982072045598,-0.906083163548422,-0.22216432068703482,1.3536292924938709,0.33452611576463864,-0.34089288926430916,0.06384250748914849,-2.0378507439803,-0.5236513396667263,0.9681807864168185,-0.16372948749216756,3.744431287238993,-0.10591263929674817,-0.10591263929674817,-0.4621081592112762,-0.16372948749216756,0.8306316454399105,0.17394576765407171,0.06384250748914849,-0.34089288926430916,0.11919997011538998,0.228081190180689,-0.6486147893595557,-0.5858198190406446,-1.0386067543300004,-0.2812183777015856,0.6393489264185823,0.38683824468201267,-0.04871252906513763,0.5401492501085412,-1.0386067543300004,0.33452611576463864,0.4385452506124256,-0.22216432068703482,-0.22216432068703482,-1.311278575581721,3.7024803541208557,0.06384250748914849,-0.906083163548422,-0.906083163548422,-0.34089288926430916,0.06384250748914849,-0.906083163548422,0.17394576765407171,-1.451444818165324,0.2816075367943659,-0.04871252906513763,0.2816075367943659,-0.4011890781327106,-0.906083163548422,-0.16372948749216756,0.688050566378247,0.4385452506124256,-0.2812183777015856,-0.2812183777015856,0.5900489466309929,0.228081190180689,-0.7760889340064466,-0.4011890781327106,4.758390219688548,0.11919997011538998,1.229406481355582,0.9681807864168185,2.410780403978149,-0.8407704557687973,0.8770244243066478,-0.16372948749216756,0.688050566378247,-0.4011890781327106,-0.4621081592112762,0.228081190180689,3.4162772870291325,0.007872098580347686,0.007872098580347686,-0.7760889340064466,-2.1909305126679395,1.434245143990909,0.5900489466309929 2937 Secondary active transmembrane transporter activity 8 16 2.76620269374964 0.0056713271897241 P12235,P53985,Q15758,Q9Y6M7,P55011,P51790,P51798,P08195 Functions GO Molecular function msigdb_gomf 391,276,310,72,138,49,115,144 1452,1223,144,391,1458,49,115,1922,276,138,1604,1261,310,549,1200,72 -0.04871252906513763,0.06384250748914849,1.2712655154383892,0.688050566378247,-0.04871252906513763,2.618889115071512,1.473918375909616,-0.2812183777015856,0.8770244243066478,1.3126701679029467,-0.10591263929674817,0.06384250748914849,0.8306316454399105,0.5401492501085412,0.11919997011538998,2.057376685439682 2937 Vacuolar transport 6 38 2.726925389304754 0.0063927492269257 P07602,P13473,Q14108,P11717,O15118,P11279 Processes and pathways GO Biological process msigdb_gobp 3,36,8,44,75,48 1020,1115,2373,75,2105,3,1457,48,44,36,152,1051,1052,2478,1149,8,2337,1169,1624,615,682,498,2174,1976,2760,1760,502,846,852,2188,697,2922,1009,933,1201,2368,935,1014 0.17394576765407171,0.11919997011538998,-0.5858198190406446,1.9547430671585866,-0.4011890781327106,5.131894866624145,-0.04871252906513763,2.618889115071512,2.94951498403428,3.4162772870291325,1.229406481355582,0.17394576765407171,0.17394576765407171,-0.6486147893595557,0.11919997011538998,4.712282471751374,-0.5236513396667263,0.11919997011538998,-0.10591263929674817,0.48964847025575964,0.4385452506124256,0.5900489466309929,-0.4011890781327106,-0.2812183777015856,-1.0386067543300004,-0.16372948749216756,0.5900489466309929,0.33452611576463864,0.33452611576463864,-0.4011890781327106,0.4385452506124256,-3.510150275167924,0.228081190180689,0.2816075367943659,0.11919997011538998,-0.5236513396667263,0.2816075367943659,0.228081190180689 2937 Hypotension 7 27 2.724342084346117 0.0064429733600765 P07602,O43772,P35610,Q13423,P04062,P07686,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,12,53,117,86,61,95 939,1443,12,269,1787,86,3,61,95,133,1586,2466,53,2741,1590,2317,443,736,1490,117,1065,1276,1967,498,2669,2188,2905 0.228081190180689,-0.04871252906513763,4.2103839880354075,0.8770244243066478,-0.22216432068703482,1.8491689704918812,5.131894866624145,2.1898966319486153,1.7404982072045598,1.3536292924938709,-0.10591263929674817,-0.6486147893595557,2.589890921013961,-1.0386067543300004,-0.10591263929674817,-0.5236513396667263,0.6393489264185823,0.38683824468201267,-0.04871252906513763,1.473918375909616,0.17394576765407171,0.06384250748914849,-0.2812183777015856,0.5900489466309929,-0.8407704557687973,-0.4011890781327106,-2.1909305126679395 2937 Chemical homeostasis 28 154 2.7233017351398137 0.0064632997034912 Q8N511,O75503,P42785,P55011,O15164,Q5BJF2,Q8WTV0,O60826,P50897,Q9H4A3,P17174,P30519,Q9UM00,P02786,P51790,P35610,P09601,P07686,P61916,Q9Y6M7,O95342,O15260,Q9NQC3,O15118,P30536,P04062,Q99808,P51572 Processes and pathways GO Biological process msigdb_gobp 131,4,5,138,10,11,14,143,22,160,151,153,172,41,49,53,173,61,62,72,69,185,208,75,82,86,99,122 2768,1020,1882,1115,1437,75,10,2376,185,706,1217,143,434,4,2452,2832,2897,1452,1669,69,574,1344,41,86,1346,2207,1895,2789,389,712,578,61,1896,2117,954,173,1582,2119,1226,1350,1229,1230,957,583,151,1035,1132,1461,2681,1686,1135,2023,871,2682,804,1038,872,1136,153,82,806,53,2127,2471,1473,5,875,1248,1915,2317,22,1051,726,122,49,1145,2539,879,276,1369,138,2226,1149,62,1704,1058,2877,365,2646,2593,204,2480,2140,2872,485,1936,2691,1497,1498,980,895,1832,2824,1163,1725,984,2407,2333,830,11,406,1843,1955,2496,2837,131,758,549,2256,14,314,2934,413,1294,838,997,1089,920,2609,99,2564,1407,774,1864,775,160,318,262,208,2185,630,377,1107,2782,2090,1872,172,2370,430,1016,512,2623,1557,72 -1.1058199287517425,0.17394576765407171,-0.2812183777015856,0.11919997011538998,-0.04871252906513763,1.9547430671585866,4.369343782243772,-0.5858198190406446,1.101010637080487,0.38683824468201267,0.06384250748914849,1.2712655154383892,0.6393489264185823,4.878143286316388,-0.6486147893595557,-1.3810415738737563,-2.0378507439803,-0.04871252906513763,-0.16372948749216756,2.057376685439682,0.48964847025575964,0.007872098580347686,3.1288971739076072,1.8491689704918812,0.007872098580347686,-0.4621081592112762,-0.2812183777015856,-1.1736688722168886,0.688050566378247,0.38683824468201267,0.48964847025575964,2.1898966319486153,-0.2812183777015856,-0.4011890781327106,0.228081190180689,1.1442885584140452,-0.10591263929674817,-0.4011890781327106,0.06384250748914849,0.007872098580347686,0.06384250748914849,0.06384250748914849,0.228081190180689,0.48964847025575964,1.229406481355582,0.17394576765407171,0.11919997011538998,-0.04871252906513763,-0.906083163548422,-0.16372948749216756,0.11919997011538998,-0.34089288926430916,0.2816075367943659,-0.906083163548422,0.33452611576463864,0.17394576765407171,0.2816075367943659,0.11919997011538998,1.229406481355582,1.8846964555914798,0.33452611576463864,2.589890921013961,-0.4011890781327106,-0.6486147893595557,-0.04871252906513763,4.863421508907323,0.2816075367943659,0.06384250748914849,-0.2812183777015856,-0.5236513396667263,3.8063874677803375,0.17394576765407171,0.38683824468201267,1.434245143990909,2.618889115071512,0.11919997011538998,-0.7120374352425395,0.2816075367943659,0.8770244243066478,0.007872098580347686,1.3126701679029467,-0.4621081592112762,0.11919997011538998,2.157214859958303,-0.16372948749216756,0.17394576765407171,-1.739482229144661,0.7361572254974664,-0.8407704557687973,-0.7760889340064466,1.057240248022844,-0.6486147893595557,-0.4011890781327106,-1.6665070292939557,0.5900489466309929,-0.2812183777015856,-0.906083163548422,-0.04871252906513763,-0.04871252906513763,0.228081190180689,0.2816075367943659,-0.22216432068703482,-1.311278575581721,0.11919997011538998,-0.16372948749216756,0.228081190180689,-0.5858198190406446,-0.5236513396667263,0.33452611576463864,4.2819961355673675,0.688050566378247,-0.22216432068703482,-0.2812183777015856,-0.6486147893595557,-1.3810415738737563,1.3941514953495935,0.38683824468201267,0.5401492501085412,-0.4621081592112762,4.192232038011874,0.8306316454399105,-9.372190307676284,0.688050566378247,0.06384250748914849,0.33452611576463864,0.228081190180689,0.17394576765407171,0.2816075367943659,-0.7760889340064466,1.7035577277228184,-0.7120374352425395,0.007872098580347686,0.38683824468201267,-0.22216432068703482,0.38683824468201267,1.229406481355582,0.8306316454399105,0.9228702829555585,1.057240248022844,-0.4011890781327106,0.48964847025575964,0.7361572254974664,0.17394576765407171,-1.1058199287517425,-0.34089288926430916,-0.22216432068703482,1.1870839548927827,-0.5236513396667263,0.688050566378247,0.228081190180689,0.5900489466309929,-0.7760889340064466,-0.04871252906513763,2.057376685439682 2937 Abnormal femoral neck head morphology 11 42 2.719213547239149 0.0065437346409893 Q96HY6,Q14739,P16278,Q7LGA3,P55011,Q96AY3,O75844,Q9Y487,Q9Y619,Q96L58,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 346,35,37,344,138,105,19,430,127,196,30 1563,1118,1663,2009,2112,2299,19,575,1894,30,37,1905,964,872,2315,1590,2536,1591,2640,138,594,35,983,897,2406,449,2251,344,1735,1294,105,346,196,1091,1403,1538,1986,851,2709,430,1878,127 -0.10591263929674817,0.11919997011538998,-0.16372948749216756,-0.34089288926430916,-0.4011890781327106,-0.5236513396667263,3.926946339483657,0.48964847025575964,-0.2812183777015856,3.6169723053440874,3.4162772870291325,-0.2812183777015856,0.228081190180689,0.2816075367943659,-0.5236513396667263,-0.10591263929674817,-0.7120374352425395,-0.10591263929674817,-0.8407704557687973,1.3126701679029467,0.48964847025575964,3.4391717680711436,0.228081190180689,0.2816075367943659,-0.5858198190406446,0.6393489264185823,-0.4621081592112762,0.7836800160884329,-0.16372948749216756,0.06384250748914849,1.628562285011634,0.7836800160884329,1.101010637080487,0.17394576765407171,0.007872098580347686,-0.04871252906513763,-0.2812183777015856,0.33452611576463864,-0.906083163548422,0.688050566378247,-0.22216432068703482,1.434245143990909 2937 Abnormal diaphysis morphology 14 61 2.7186172932682786 0.0065555408421169 Q96HY6,Q14739,Q99622,P16278,Q16851,P12955,Q6NW34,Q96AY3,Q32P28,P51798,Q9NR77,Q9Y619,Q96L58,Q9H1A4 Drugs and Diseases Human Phenotype Ontology msigdb_hp 346,35,315,37,168,187,343,105,80,115,57,127,196,260 939,1778,942,1889,1663,2009,2299,1123,1027,1674,187,37,1352,1132,1905,523,964,872,1468,2684,1142,527,1590,2536,2034,970,115,2640,1150,596,2594,484,2140,1494,35,983,1503,1165,168,80,343,2058,344,1735,678,1742,105,346,196,1968,315,260,57,2182,851,2287,1773,430,2802,1878,127 0.228081190180689,-0.22216432068703482,0.228081190180689,-0.2812183777015856,-0.16372948749216756,-0.34089288926430916,-0.5236513396667263,0.11919997011538998,0.17394576765407171,-0.16372948749216756,1.101010637080487,3.4162772870291325,0.007872098580347686,0.11919997011538998,-0.2812183777015856,0.5401492501085412,0.228081190180689,0.2816075367943659,-0.04871252906513763,-0.906083163548422,0.11919997011538998,0.5401492501085412,-0.10591263929674817,-0.7120374352425395,-0.34089288926430916,0.228081190180689,1.473918375909616,-0.8407704557687973,0.11919997011538998,0.48964847025575964,-0.7760889340064466,0.5900489466309929,-0.4011890781327106,-0.04871252906513763,3.4391717680711436,0.228081190180689,-0.04871252906513763,0.11919997011538998,1.1870839548927827,1.919885894471246,0.7836800160884329,-0.34089288926430916,0.7836800160884329,-0.16372948749216756,0.4385452506124256,-0.16372948749216756,1.628562285011634,0.7836800160884329,1.101010637080487,-0.2812183777015856,0.8306316454399105,0.9228702829555585,2.410780403978149,-0.4011890781327106,0.33452611576463864,-0.4621081592112762,-0.16372948749216756,0.688050566378247,-1.1736688722168886,-0.22216432068703482,1.434245143990909 2937 Endosome membrane 30 101 2.7170136967946155 0.0065873881540543 Q15286,Q96SU4,P04439,Q969E2,Q93050,Q14108,O14828,Q9Y487,Q92542,P42892,P61006,O15400,O43795,O75165,P13473,Q7Z3U7,P02786,P11717,Q9H4M9,P11279,P51790,O60493,Q8IV08,O95342,Q9UNH7,Q99805,O15118,P09496,O15127,P01889 Localization GO Cellular component msigdb_gocc 256,416,128,135,413,8,249,430,158,25,395,383,385,269,36,311,41,44,318,48,49,293,63,69,352,207,75,326,113,120 2624,1115,249,75,113,383,385,293,1218,570,2582,269,2831,2114,69,1670,120,41,2680,128,797,2304,1896,326,2923,48,44,36,2022,716,1232,1909,2885,659,25,1143,1051,1919,49,1052,2899,395,1373,972,1149,818,1062,1718,1158,2750,2653,8,1382,256,1725,984,2337,406,1169,1624,311,63,2498,615,158,413,135,1747,2562,498,416,998,207,2174,1531,1976,2074,2760,1760,502,318,852,2866,697,2922,2284,1009,1548,1312,2859,1768,1770,2574,702,2368,2708,352,935,2672,430,2711 -0.8407704557687973,0.11919997011538998,0.9228702829555585,1.9547430671585866,1.473918375909616,0.688050566378247,0.688050566378247,0.8306316454399105,0.06384250748914849,0.48964847025575964,-0.7760889340064466,0.8770244243066478,-1.3810415738737563,-0.4011890781327106,2.057376685439682,-0.16372948749216756,1.434245143990909,3.1288971739076072,-0.906083163548422,1.3941514953495935,0.33452611576463864,-0.5236513396667263,-0.2812183777015856,0.7836800160884329,-3.598238387349531,2.618889115071512,2.94951498403428,3.4162772870291325,-0.34089288926430916,0.38683824468201267,0.06384250748914849,-0.2812183777015856,-1.8873708060077286,0.4385452506124256,3.744431287238993,0.11919997011538998,0.17394576765407171,-0.2812183777015856,2.618889115071512,0.17394576765407171,-2.0378507439803,0.688050566378247,0.007872098580347686,0.228081190180689,0.11919997011538998,0.33452611576463864,0.17394576765407171,-0.16372948749216756,0.11919997011538998,-1.0386067543300004,-0.8407704557687973,4.712282471751374,0.007872098580347686,0.9228702829555585,-0.16372948749216756,0.228081190180689,-0.5236513396667263,0.688050566378247,0.11919997011538998,-0.10591263929674817,0.8306316454399105,2.157214859958303,-0.6486147893595557,0.48964847025575964,1.229406481355582,0.688050566378247,1.3536292924938709,-0.16372948749216756,-0.7120374352425395,0.5900489466309929,0.688050566378247,0.228081190180689,1.057240248022844,-0.4011890781327106,-0.04871252906513763,-0.2812183777015856,-0.34089288926430916,-1.0386067543300004,-0.16372948749216756,0.5900489466309929,0.8306316454399105,0.33452611576463864,-1.5941764518204824,0.4385452506124256,-3.510150275167924,-0.4621081592112762,0.228081190180689,-0.04871252906513763,0.06384250748914849,-1.5224894117754426,-0.16372948749216756,-0.16372948749216756,-0.7120374352425395,0.4385452506124256,-0.5236513396667263,-0.906083163548422,0.7836800160884329,0.2816075367943659,-0.8407704557687973,0.688050566378247,-0.906083163548422 2937 Clathrin coated vesicle 14 42 2.714330485129916 0.0066409878205129 Q5VW38,Q9BVK6,Q15286,P49755,Q14108,P02786,P11717,Q9NVZ3,O60493,P09496,P51572,P42892,P20645,P50570 Localization GO Cellular component msigdb_gocc 88,418,256,274,8,41,44,320,293,326,122,25,152,303 1020,1207,1563,2105,293,2114,1670,41,326,798,1457,44,716,152,25,274,303,1919,122,1052,2899,395,972,818,1062,1497,8,256,88,1169,1747,418,1408,1760,502,2781,320,2922,1551,1768,1316,2001 0.17394576765407171,0.06384250748914849,-0.10591263929674817,-0.4011890781327106,0.8306316454399105,-0.4011890781327106,-0.16372948749216756,3.1288971739076072,0.7836800160884329,0.33452611576463864,-0.04871252906513763,2.94951498403428,0.38683824468201267,1.229406481355582,3.744431287238993,0.8770244243066478,0.8306316454399105,-0.2812183777015856,1.434245143990909,0.17394576765407171,-2.0378507439803,0.688050566378247,0.228081190180689,0.33452611576463864,0.17394576765407171,-0.04871252906513763,4.712282471751374,0.9228702829555585,1.8491689704918812,0.11919997011538998,-0.16372948749216756,0.688050566378247,0.007872098580347686,-0.16372948749216756,0.5900489466309929,-1.1058199287517425,0.8306316454399105,-3.510150275167924,-0.04871252906513763,-0.16372948749216756,0.06384250748914849,-0.2812183777015856 2937 Abnormal tongue morphology 12 65 2.713130517294187 0.0066650849432399 P10253,P16278,P20700,Q9UBM7,Q01433,O15460,O75844,O60826,Q6NUK1,P01889,P07686,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,37,133,38,103,200,19,143,220,120,61,30 939,1563,1434,1021,467,200,143,2009,1783,19,1573,120,1894,30,61,2526,129,37,133,961,1905,1688,872,2684,529,2771,1590,2536,2034,726,2229,595,1150,2138,596,103,1262,538,540,598,1501,2775,1503,1510,220,2699,344,1294,1852,2067,1091,2569,2428,1539,1540,1194,2085,38,2287,2802,1999,248,1556,2711,513 0.228081190180689,-0.10591263929674817,-0.04871252906513763,0.17394576765407171,0.5900489466309929,1.057240248022844,1.2712655154383892,-0.34089288926430916,-0.22216432068703482,3.926946339483657,-0.10591263929674817,1.434245143990909,-0.2812183777015856,3.6169723053440874,2.1898966319486153,-0.7120374352425395,1.3941514953495935,3.4162772870291325,1.3536292924938709,0.228081190180689,-0.2812183777015856,-0.16372948749216756,0.2816075367943659,-0.906083163548422,0.5401492501085412,-1.1058199287517425,-0.10591263929674817,-0.7120374352425395,-0.34089288926430916,0.38683824468201267,-0.4621081592112762,0.48964847025575964,0.11919997011538998,-0.4011890781327106,0.48964847025575964,1.628562285011634,0.06384250748914849,0.5401492501085412,0.5401492501085412,0.48964847025575964,-0.04871252906513763,-1.1058199287517425,-0.04871252906513763,-0.04871252906513763,1.0129671489863166,-0.906083163548422,0.7836800160884329,0.06384250748914849,-0.22216432068703482,-0.34089288926430916,0.17394576765407171,-0.7120374352425395,-0.5858198190406446,-0.04871252906513763,-0.04871252906513763,0.11919997011538998,-0.34089288926430916,3.4162772870291325,-0.4621081592112762,-1.1736688722168886,-0.2812183777015856,0.9681807864168185,-0.04871252906513763,-0.906083163548422,0.5900489466309929 2937 Diarrhea 14 71 2.711848833696352 0.006690909833513 O60934,O95342,P02786,P54802,P38571,P15586,P35610,O60762,Q13510,Q13423,P42892,P01889,P07686,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 186,69,41,42,17,20,53,228,55,117,25,120,61,31 2003,228,186,1445,1787,69,2458,120,41,2206,31,61,2118,2459,1584,20,1684,646,1586,2466,2929,1357,2589,53,2741,1361,2314,17,1244,1473,25,1590,725,877,362,971,42,1054,594,2791,1932,1712,117,2691,55,1718,1066,1266,1163,1835,1068,746,404,750,1735,2753,2813,1283,1289,1746,2500,453,1294,374,2609,316,260,1538,1767,511,2623 -0.34089288926430916,0.9681807864168185,1.101010637080487,-0.04871252906513763,-0.22216432068703482,2.057376685439682,-0.6486147893595557,1.434245143990909,3.1288971739076072,-0.4621081592112762,3.6169723053440874,2.1898966319486153,-0.4011890781327106,-0.6486147893595557,-0.10591263929674817,3.887244197186541,-0.16372948749216756,0.4385452506124256,-0.10591263929674817,-0.6486147893595557,-6.1260774561706235,0.007872098580347686,-0.7760889340064466,2.589890921013961,-1.0386067543300004,0.007872098580347686,-0.5236513396667263,3.9856208887046614,0.06384250748914849,-0.04871252906513763,3.744431287238993,-0.10591263929674817,0.38683824468201267,0.2816075367943659,0.7361572254974664,0.228081190180689,3.078582353860239,0.17394576765407171,0.48964847025575964,-1.1736688722168886,-0.2812183777015856,-0.16372948749216756,1.473918375909616,-0.906083163548422,2.5014551385438826,-0.16372948749216756,0.17394576765407171,0.06384250748914849,0.11919997011538998,-0.22216432068703482,0.17394576765407171,0.38683824468201267,0.688050566378247,0.38683824468201267,-0.16372948749216756,-1.0386067543300004,-1.2421547136861633,0.06384250748914849,0.06384250748914849,-0.16372948749216756,-0.6486147893595557,0.6393489264185823,0.06384250748914849,0.7361572254974664,-0.7760889340064466,0.8306316454399105,0.9228702829555585,-0.04871252906513763,-0.16372948749216756,0.5900489466309929,-0.7760889340064466 2937 Abnormal form of the vertebral bodies 17 80 2.705601527470032 0.0068180803133137 Q9UM00,Q14739,P16278,Q9UBM7,Q9Y619,Q96AY3,P54802,Q9UBN7,Q32P28,P51798,P15586,O60826,Q6NUK1,Q15125,P48735,Q96L58,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 172,35,37,38,127,105,42,210,80,115,20,143,220,26,216,196,30 939,1778,942,1438,1334,1118,143,1663,212,948,1452,575,2015,30,1674,714,20,37,1352,646,961,1905,523,2531,2929,964,1468,2684,2898,527,2315,333,2885,1590,216,970,115,2640,42,594,2400,1150,2042,1931,484,538,445,1156,2691,35,983,1503,26,1269,745,80,986,220,449,343,2844,1280,1515,105,346,196,1091,1982,1986,851,38,210,1108,2287,172,1649,2621,2709,2802,127 0.228081190180689,-0.22216432068703482,0.228081190180689,-0.04871252906513763,0.007872098580347686,0.11919997011538998,1.2712655154383892,-0.16372948749216756,1.0129671489863166,0.228081190180689,-0.04871252906513763,0.48964847025575964,-0.34089288926430916,3.6169723053440874,-0.16372948749216756,0.38683824468201267,3.887244197186541,3.4162772870291325,0.007872098580347686,0.4385452506124256,0.228081190180689,-0.2812183777015856,0.5401492501085412,-0.7120374352425395,-6.1260774561706235,0.228081190180689,-0.04871252906513763,-0.906083163548422,-2.0378507439803,0.5401492501085412,-0.5236513396667263,0.7836800160884329,-1.8873708060077286,-0.10591263929674817,1.0129671489863166,0.228081190180689,1.473918375909616,-0.8407704557687973,3.078582353860239,0.48964847025575964,-0.5858198190406446,0.11919997011538998,-0.34089288926430916,-0.2812183777015856,0.5900489466309929,0.5401492501085412,0.6393489264185823,0.11919997011538998,-0.906083163548422,3.4391717680711436,0.228081190180689,-0.04871252906513763,3.7024803541208557,0.06384250748914849,0.38683824468201267,1.919885894471246,0.228081190180689,1.0129671489863166,0.6393489264185823,0.7836800160884329,-1.451444818165324,0.06384250748914849,-0.04871252906513763,1.628562285011634,0.7836800160884329,1.101010637080487,0.17394576765407171,-0.2812183777015856,-0.2812183777015856,0.33452611576463864,3.4162772870291325,1.057240248022844,0.17394576765407171,-0.4621081592112762,1.1870839548927827,-0.10591263929674817,-0.7760889340064466,-0.906083163548422,-1.1736688722168886,1.434245143990909 2937 metalloprotease 6 26 2.688670750102488 0.007173713669589 Q9UIQ6,Q7Z2K6,P02786,O75844,Q5JRX3,P42892 Functions Panther Protein class panther_protein_class 2,98,41,19,157,25 790,2627,19,2013,41,187,1682,1233,1796,2029,25,2395,663,538,157,98,1514,496,1530,2733,773,2762,627,2187,2,1016 0.33452611576463864,-0.8407704557687973,3.926946339483657,-0.34089288926430916,3.1288971739076072,1.101010637080487,-0.16372948749216756,0.06384250748914849,-0.22216432068703482,-0.34089288926430916,3.744431287238993,-0.5858198190406446,0.4385452506124256,0.5401492501085412,1.229406481355582,1.7035577277228184,-0.04871252906513763,0.5900489466309929,-0.04871252906513763,-0.9720282133639213,0.38683824468201267,-1.0386067543300004,0.48964847025575964,-0.4011890781327106,5.198840694526526,0.228081190180689 2937 Abnormal vascular physiology 9 47 2.676779237225495 0.007433359544968 Q14739,Q14108,O15460,O75844,P51798,Q6NUK1,P04062,P01889,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,8,200,19,115,220,86,120,31 1563,200,1118,1569,1890,19,1789,2458,120,1894,86,2206,31,1900,646,1687,1905,523,2215,804,2637,1360,2684,1473,1367,115,593,2643,1150,1931,2749,2691,8,1162,35,1503,2551,220,2699,2159,1193,2187,2287,785,1319,2802,248 -0.10591263929674817,1.057240248022844,0.11919997011538998,-0.10591263929674817,-0.2812183777015856,3.926946339483657,-0.22216432068703482,-0.6486147893595557,1.434245143990909,-0.2812183777015856,1.8491689704918812,-0.4621081592112762,3.6169723053440874,-0.2812183777015856,0.4385452506124256,-0.16372948749216756,-0.2812183777015856,0.5401492501085412,-0.4621081592112762,0.33452611576463864,-0.8407704557687973,0.007872098580347686,-0.906083163548422,-0.04871252906513763,0.007872098580347686,1.473918375909616,0.48964847025575964,-0.8407704557687973,0.11919997011538998,-0.2812183777015856,-1.0386067543300004,-0.906083163548422,4.712282471751374,0.11919997011538998,3.4391717680711436,-0.04871252906513763,-0.7120374352425395,1.0129671489863166,-0.906083163548422,-0.4011890781327106,0.11919997011538998,-0.4011890781327106,-0.4621081592112762,0.38683824468201267,0.06384250748914849,-1.1736688722168886,0.9681807864168185 2937 Protease 15 83 2.673937561748171 0.0074966407616536 Q9HB40,Q9H3G5,Q9UIQ6,O75976,Q7Z2K6,P42785,Q5JRX3,P12955,P28072,O75844,Q4J6C6,O14773,P42892,P10619,P67812 Functions Protein Atlas Molecular function protein_atlas_molecular_function 0,1,2,34,98,5,157,187,163,19,85,24,25,58,59 1562,466,24,790,2627,19,34,387,2524,2013,1128,1583,58,187,1682,1901,163,1355,1796,1136,527,2885,2927,5,25,2129,2130,2476,2912,2395,1812,203,1250,663,729,59,2930,2237,403,1381,2597,672,85,157,2248,2751,2843,98,2415,1626,680,2889,761,553,1181,2500,374,2168,2269,839,496,1530,843,2609,2733,773,1,1983,847,0,2762,1642,851,627,2187,1198,2,2619,380,2515,1016,1652,2516 -0.10591263929674817,0.5900489466309929,3.7652112572324823,0.33452611576463864,-0.8407704557687973,3.926946339483657,3.4391717680711436,0.688050566378247,-0.7120374352425395,-0.34089288926430916,0.11919997011538998,-0.10591263929674817,2.3177619175977977,1.101010637080487,-0.16372948749216756,-0.2812183777015856,1.1870839548927827,0.007872098580347686,-0.22216432068703482,0.11919997011538998,0.5401492501085412,-1.8873708060077286,-4.421251316217688,4.863421508907323,3.744431287238993,-0.4011890781327106,-0.4011890781327106,-0.6486147893595557,-2.425443155290095,-0.5858198190406446,-0.22216432068703482,1.057240248022844,0.06384250748914849,0.4385452506124256,0.38683824468201267,2.222287625540094,-6.2325523544671535,-0.4621081592112762,0.688050566378247,0.007872098580347686,-0.7760889340064466,0.4385452506124256,1.8846964555914798,1.229406481355582,-0.4621081592112762,-1.0386067543300004,-1.451444818165324,1.7035577277228184,-0.5858198190406446,-0.10591263929674817,0.4385452506124256,-1.8873708060077286,0.38683824468201267,0.5401492501085412,0.11919997011538998,-0.6486147893595557,0.7361572254974664,-0.4011890781327106,-0.4621081592112762,0.33452611576463864,0.5900489466309929,-0.04871252906513763,0.33452611576463864,-0.7760889340064466,-0.9720282133639213,0.38683824468201267,5.830215713580066,-0.2812183777015856,0.33452611576463864,5.893957451831641,-1.0386067543300004,-0.10591263929674817,0.33452611576463864,0.48964847025575964,-0.4011890781327106,0.11919997011538998,5.198840694526526,-0.7760889340064466,0.7361572254974664,-0.6486147893595557,0.228081190180689,-0.10591263929674817,-0.6486147893595557 2937 Diseases of glycosylation 8 20 2.672025424627846 0.0075394935775769 P16278,O43505,Q14376,P06865,O60762,Q96L58,P10619,P07686 Processes and pathways Reactome Pathways msigdb_reactome 37,76,147,16,228,196,58,61 76,228,517,1024,16,61,58,37,2589,1362,1920,484,2046,826,147,2599,2161,196,316,2093 1.9547430671585866,0.9681807864168185,0.5401492501085412,0.17394576765407171,4.024165938684547,2.1898966319486153,2.3177619175977977,3.4162772870291325,-0.7760889340064466,0.007872098580347686,-0.2812183777015856,0.5900489466309929,-0.34089288926430916,0.33452611576463864,1.2712655154383892,-0.7760889340064466,-0.4011890781327106,1.101010637080487,0.8306316454399105,-0.34089288926430916 2937 Generalized onset seizure 22 94 2.668414282927603 0.0076210222042536 P07602,O75503,Q00577,O94979,Q14108,P55011,Q8WVX9,P16278,Q4G176,Q9H7D7,Q13510,Q969N2,P52788,P11166,P15311,P04062,Q96N66,Q9Y320,O60762,Q9BZI7,Q9Y619,Q01105 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,4,254,250,8,138,410,37,404,319,55,453,70,437,439,86,242,379,228,125,127,123 1326,1329,1441,789,2107,2379,2626,1886,228,4,1666,250,2714,2456,1125,86,1576,1895,3,437,439,37,1684,646,1794,1688,1463,1907,872,1357,2534,526,2471,588,810,2886,2318,1249,2036,2808,2640,70,1053,138,2229,595,254,1062,123,2649,1712,1935,55,8,1940,669,1829,2051,404,2337,2698,1071,2699,1955,1513,1286,410,1181,453,1747,1966,1749,1968,242,1401,1859,125,319,1539,1763,2508,851,2360,696,2188,1010,1548,2904,2091,509,379,1431,1016,127 0.007872098580347686,0.007872098580347686,-0.04871252906513763,0.33452611576463864,-0.4011890781327106,-0.5858198190406446,-0.8407704557687973,-0.2812183777015856,0.9681807864168185,4.878143286316388,-0.16372948749216756,0.9228702829555585,-0.9720282133639213,-0.6486147893595557,0.11919997011538998,1.8491689704918812,-0.10591263929674817,-0.2812183777015856,5.131894866624145,0.6393489264185823,0.6393489264185823,3.4162772870291325,-0.16372948749216756,0.4385452506124256,-0.22216432068703482,-0.16372948749216756,-0.04871252906513763,-0.2812183777015856,0.2816075367943659,0.007872098580347686,-0.7120374352425395,0.5401492501085412,-0.6486147893595557,0.48964847025575964,0.33452611576463864,-1.8873708060077286,-0.5236513396667263,0.06384250748914849,-0.34089288926430916,-1.2421547136861633,-0.8407704557687973,2.057376685439682,0.17394576765407171,1.3126701679029467,-0.4621081592112762,0.48964847025575964,0.9228702829555585,0.17394576765407171,1.434245143990909,-0.8407704557687973,-0.16372948749216756,-0.2812183777015856,2.5014551385438826,4.712282471751374,-0.2812183777015856,0.4385452506124256,-0.22216432068703482,-0.34089288926430916,0.688050566378247,-0.5236513396667263,-0.906083163548422,0.17394576765407171,-0.906083163548422,-0.2812183777015856,-0.04871252906513763,0.06384250748914849,0.688050566378247,0.11919997011538998,0.6393489264185823,-0.16372948749216756,-0.2812183777015856,-0.16372948749216756,-0.2812183777015856,0.9681807864168185,0.007872098580347686,-0.22216432068703482,1.434245143990909,0.8306316454399105,-0.04871252906513763,-0.16372948749216756,-0.6486147893595557,0.33452611576463864,-0.5236513396667263,0.4385452506124256,-0.4011890781327106,0.228081190180689,-0.04871252906513763,-2.1909305126679395,-0.34089288926430916,0.5900489466309929,0.7361572254974664,0.007872098580347686,0.228081190180689,1.434245143990909 2937 Dementia 17 57 2.667908992602265 0.0076324929347373 P07602,P20700,Q14108,Q9Y4U1,Q9NQZ5,Q04446,O15118,P06865,Q9Y487,Q8WVX9,Q13510,O96008,P04062,P35637,O75165,P61916,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,133,8,248,246,443,75,16,430,410,55,297,86,359,269,62,95 1326,75,1443,1661,269,2832,297,2458,86,1576,1347,16,3,2527,2305,95,133,1688,1462,1235,2534,1690,359,967,2127,875,1589,1249,971,1815,2478,62,443,736,1490,2546,55,8,1065,2335,1276,2921,913,410,1746,763,498,997,2609,2173,246,2188,1010,2845,2622,430,248 0.007872098580347686,1.9547430671585866,-0.04871252906513763,-0.16372948749216756,0.8770244243066478,-1.3810415738737563,0.8306316454399105,-0.6486147893595557,1.8491689704918812,-0.10591263929674817,0.007872098580347686,4.024165938684547,5.131894866624145,-0.7120374352425395,-0.5236513396667263,1.7404982072045598,1.3536292924938709,-0.16372948749216756,-0.04871252906513763,0.06384250748914849,-0.7120374352425395,-0.16372948749216756,0.7361572254974664,0.228081190180689,-0.4011890781327106,0.2816075367943659,-0.10591263929674817,0.06384250748914849,0.228081190180689,-0.22216432068703482,-0.6486147893595557,2.157214859958303,0.6393489264185823,0.38683824468201267,-0.04871252906513763,-0.7120374352425395,2.5014551385438826,4.712282471751374,0.17394576765407171,-0.5236513396667263,0.06384250748914849,-3.510150275167924,0.2816075367943659,0.688050566378247,-0.16372948749216756,0.38683824468201267,0.5900489466309929,0.228081190180689,-0.7760889340064466,-0.4011890781327106,0.9681807864168185,-0.4011890781327106,0.228081190180689,-1.451444818165324,-0.7760889340064466,0.688050566378247,0.9681807864168185 2937 Transport vesicle 24 79 2.659251756819873 0.0078314418790088 Q9BVK6,Q15286,P04439,Q96A57,O94979,Q9Y296,Q9Y678,P50897,Q92542,P61006,P20645,P49257,P49755,P11717,P11279,P51790,Q13190,O15260,P24390,Q15363,P09496,Q8TBA6,O15498,P01889 Localization GO Cellular component msigdb_gocc 418,256,128,414,250,425,432,22,158,395,152,272,274,44,48,49,306,185,74,339,326,373,227,120 1326,2102,2579,185,383,227,2105,1116,1218,1335,517,1219,2010,2832,250,951,1670,120,128,326,798,2923,48,44,1686,716,152,74,2682,1465,1141,2127,1591,272,274,22,1051,1919,49,1052,2134,1924,1147,1925,395,1373,972,1149,1601,1059,1062,306,1497,2750,1720,2327,602,256,1725,339,745,984,373,158,682,553,414,768,418,2781,1866,1311,2618,1107,425,2293,432,2623,636 0.007872098580347686,-0.4011890781327106,-0.7760889340064466,1.101010637080487,0.688050566378247,0.9681807864168185,-0.4011890781327106,0.11919997011538998,0.06384250748914849,0.007872098580347686,0.5401492501085412,0.06384250748914849,-0.34089288926430916,-1.3810415738737563,0.9228702829555585,0.228081190180689,-0.16372948749216756,1.434245143990909,1.3941514953495935,0.7836800160884329,0.33452611576463864,-3.598238387349531,2.618889115071512,2.94951498403428,-0.16372948749216756,0.38683824468201267,1.229406481355582,1.9892736116862897,-0.906083163548422,-0.04871252906513763,0.11919997011538998,-0.4011890781327106,-0.10591263929674817,0.8770244243066478,0.8770244243066478,3.8063874677803375,0.17394576765407171,-0.2812183777015856,2.618889115071512,0.17394576765407171,-0.4011890781327106,-0.2812183777015856,0.11919997011538998,-0.2812183777015856,0.688050566378247,0.007872098580347686,0.228081190180689,0.11919997011538998,-0.10591263929674817,0.17394576765407171,0.17394576765407171,0.8306316454399105,-0.04871252906513763,-1.0386067543300004,-0.16372948749216756,-0.5236513396667263,0.48964847025575964,0.9228702829555585,-0.16372948749216756,0.7836800160884329,0.38683824468201267,0.228081190180689,0.7361572254974664,1.229406481355582,0.4385452506124256,0.5401492501085412,0.688050566378247,0.38683824468201267,0.688050566378247,-1.1058199287517425,-0.22216432068703482,0.06384250748914849,-0.7760889340064466,0.17394576765407171,0.688050566378247,-0.4621081592112762,0.688050566378247,-0.7760889340064466,0.48964847025575964 2937 Anion transmembrane transporter activity 18 40 2.6540097895419983 0.0079541519212222 O95563,P12235,P53985,P21796,Q15758,P11166,Q9Y6M7,Q99808,P55011,Q9Y619,Q9H2D1,P51790,P51798,P08195,Q14728,Q6NUK1,Q8TB61,Q96S66 Functions GO Molecular function msigdb_gomf 574,391,276,394,310,437,72,99,138,127,317,49,115,144,177,220,614,685 2100,1437,1443,862,1570,574,1223,144,2119,437,391,1458,394,807,1365,49,115,1922,276,138,1261,177,310,2334,2727,220,2339,614,2561,685,99,1974,317,923,693,1200,1767,2292,127,72 -0.4011890781327106,-0.04871252906513763,-0.04871252906513763,0.2816075367943659,-0.10591263929674817,0.48964847025575964,0.06384250748914849,1.2712655154383892,-0.4011890781327106,0.6393489264185823,0.688050566378247,-0.04871252906513763,0.688050566378247,0.33452611576463864,0.007872098580347686,2.618889115071512,1.473918375909616,-0.2812183777015856,0.8770244243066478,1.3126701679029467,0.06384250748914849,1.1442885584140452,0.8306316454399105,-0.5236513396667263,-0.9720282133639213,1.0129671489863166,-0.5236513396667263,0.48964847025575964,-0.7120374352425395,0.4385452506124256,1.7035577277228184,-0.2812183777015856,0.8306316454399105,0.2816075367943659,0.4385452506124256,0.11919997011538998,-0.16372948749216756,-0.4621081592112762,1.434245143990909,2.057376685439682 2937 Organophosphate ester transport 7 23 2.651190377773272 0.0080208616362067 Q99808,Q14108,P08183,Q8WTV0,Q96GC9,Q6NUK1,P61916 Processes and pathways GO Biological process msigdb_gobp 99,8,13,14,118,220,62 862,1223,13,391,1458,2023,2634,480,62,886,1378,8,2334,220,614,14,118,99,688,1000,317,693,2616 0.2816075367943659,0.06384250748914849,4.192232038011874,0.688050566378247,-0.04871252906513763,-0.34089288926430916,-0.8407704557687973,0.5900489466309929,2.157214859958303,0.2816075367943659,0.007872098580347686,4.712282471751374,-0.5236513396667263,1.0129671489863166,0.48964847025575964,4.192232038011874,1.473918375909616,1.7035577277228184,0.4385452506124256,0.228081190180689,0.8306316454399105,0.4385452506124256,-0.7760889340064466 2937 Metalloprotease 6 26 2.643959269376009 0.0081942515899933 Q9UIQ6,O75976,Q7Z2K6,O75844,Q5JRX3,P42892 Functions Protein Atlas Molecular function protein_atlas_molecular_function 2,34,98,19,157,25 466,790,2627,19,34,2013,1583,187,1682,25,2395,663,157,98,553,496,1530,2733,773,1983,2762,1642,627,2187,2,1016 0.5900489466309929,0.33452611576463864,-0.8407704557687973,3.926946339483657,3.4391717680711436,-0.34089288926430916,-0.10591263929674817,1.101010637080487,-0.16372948749216756,3.744431287238993,-0.5858198190406446,0.4385452506124256,1.229406481355582,1.7035577277228184,0.5401492501085412,0.5900489466309929,-0.04871252906513763,-0.9720282133639213,0.38683824468201267,-0.2812183777015856,-1.0386067543300004,-0.10591263929674817,0.48964847025575964,-0.4011890781327106,5.198840694526526,0.228081190180689 2937 Metalloexopeptidase activity 7 20 2.640112297413155 0.0082878559917165 Q9UIQ6,O75976,Q7Z2K6,P12955,P02786,Q969V3,O75844 Functions GO Molecular function msigdb_gomf 2,34,98,187,41,285,19 19,34,41,1583,187,1796,1361,2476,663,98,285,2817,496,286,1983,2762,1642,627,2187,2 3.926946339483657,3.4391717680711436,3.1288971739076072,-0.10591263929674817,1.101010637080487,-0.22216432068703482,0.007872098580347686,-0.6486147893595557,0.4385452506124256,1.7035577277228184,0.8770244243066478,-1.2421547136861633,0.5900489466309929,0.8770244243066478,-0.2812183777015856,-1.0386067543300004,-0.10591263929674817,0.48964847025575964,-0.4011890781327106,5.198840694526526 2937 Dermatological manifestations of systemic disorders 12 67 2.6368291257257206 0.0083684974339501 Q14739,P12955,O95342,P40855,O43772,O15118,Q14376,P38571,O75844,P56589,P61916,P04066 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,187,69,164,12,75,147,17,19,174,62,30 1559,1329,75,12,1783,1890,19,1787,69,355,1125,2457,1894,30,1672,2206,578,2117,714,437,1033,799,187,2212,2681,653,2741,1361,2849,2314,17,164,1590,1248,2744,1920,2640,1922,1053,2643,174,2396,2745,62,2138,2139,1604,596,1932,2691,147,35,1505,449,750,2796,1289,1968,2501,1760,1538,1424,1767,1319,248,2905,2295 -0.10591263929674817,0.007872098580347686,1.9547430671585866,4.2103839880354075,-0.22216432068703482,-0.2812183777015856,3.926946339483657,-0.22216432068703482,2.057376685439682,0.7361572254974664,0.11919997011538998,-0.6486147893595557,-0.2812183777015856,3.6169723053440874,-0.16372948749216756,-0.4621081592112762,0.48964847025575964,-0.4011890781327106,0.38683824468201267,0.6393489264185823,0.17394576765407171,0.33452611576463864,1.101010637080487,-0.4621081592112762,-0.906083163548422,0.4385452506124256,-1.0386067543300004,0.007872098580347686,-1.5224894117754426,-0.5236513396667263,3.9856208887046614,1.1870839548927827,-0.10591263929674817,0.06384250748914849,-1.0386067543300004,-0.2812183777015856,-0.8407704557687973,-0.2812183777015856,0.17394576765407171,-0.8407704557687973,1.1442885584140452,-0.5858198190406446,-1.0386067543300004,2.157214859958303,-0.4011890781327106,-0.4011890781327106,-0.10591263929674817,0.48964847025575964,-0.2812183777015856,-0.906083163548422,1.2712655154383892,3.4391717680711436,-0.04871252906513763,0.6393489264185823,0.38683824468201267,-1.1736688722168886,0.06384250748914849,-0.2812183777015856,-0.6486147893595557,-0.16372948749216756,-0.04871252906513763,0.007872098580347686,-0.16372948749216756,0.06384250748914849,0.9681807864168185,-2.1909305126679395,-0.4621081592112762 2937 Cellular lipid catabolic process 10 60 2.633377045864143 0.0084540438964222 O95342,Q8WTV0,Q8NCC3,P06865,P35610,P50897,Q13510,P07686,P04066,P06280 Processes and pathways GO Biological process msigdb_gobp 69,14,15,16,53,22,55,61,30,31 465,292,266,2376,862,2821,948,69,1343,86,30,298,2208,31,16,61,357,1584,2212,1461,2634,718,2466,2026,653,1466,2636,2469,53,2849,1244,2535,2472,2744,877,22,2037,2540,2928,55,1832,1505,2333,1068,2339,1733,2253,2921,911,1516,15,14,763,2501,243,2356,2573,2088,1011,1109 0.5900489466309929,0.8306316454399105,0.8770244243066478,-0.5858198190406446,0.2816075367943659,-1.311278575581721,0.228081190180689,2.057376685439682,0.007872098580347686,1.8491689704918812,3.6169723053440874,0.8306316454399105,-0.4621081592112762,3.6169723053440874,4.024165938684547,2.1898966319486153,0.7361572254974664,-0.10591263929674817,-0.4621081592112762,-0.04871252906513763,-0.8407704557687973,0.38683824468201267,-0.6486147893595557,-0.34089288926430916,0.4385452506124256,-0.04871252906513763,-0.8407704557687973,-0.6486147893595557,2.589890921013961,-1.5224894117754426,0.06384250748914849,-0.7120374352425395,-0.6486147893595557,-1.0386067543300004,0.2816075367943659,3.8063874677803375,-0.34089288926430916,-0.7120374352425395,-6.020295088058086,2.5014551385438826,-0.22216432068703482,-0.04871252906513763,-0.5236513396667263,0.17394576765407171,-0.5236513396667263,-0.16372948749216756,-0.4621081592112762,-3.510150275167924,0.2816075367943659,-0.04871252906513763,4.0999276525600274,4.192232038011874,0.38683824468201267,-0.6486147893595557,0.9681807864168185,-0.5236513396667263,-0.7120374352425395,-0.34089288926430916,0.228081190180689,0.17394576765407171 2937 Lysosomal transport 6 34 2.632622970738192 0.0084728344874187 P07602,P13473,Q14108,P11717,O15118,P11279 Processes and pathways GO Biological process msigdb_gobp 3,36,8,44,75,48 1020,1115,2373,75,2105,3,1457,48,44,36,152,1051,1052,2478,8,2337,1169,1624,615,498,2174,2760,1760,502,852,2188,697,2922,1009,933,1201,2368,935,1014 0.17394576765407171,0.11919997011538998,-0.5858198190406446,1.9547430671585866,-0.4011890781327106,5.131894866624145,-0.04871252906513763,2.618889115071512,2.94951498403428,3.4162772870291325,1.229406481355582,0.17394576765407171,0.17394576765407171,-0.6486147893595557,4.712282471751374,-0.5236513396667263,0.11919997011538998,-0.10591263929674817,0.48964847025575964,0.5900489466309929,-0.4011890781327106,-1.0386067543300004,-0.16372948749216756,0.5900489466309929,0.33452611576463864,-0.4011890781327106,0.4385452506124256,-3.510150275167924,0.228081190180689,0.2816075367943659,0.11919997011538998,-0.5236513396667263,0.2816075367943659,0.228081190180689 2937 Arthritis 7 41 2.630909667039864 0.0085156667306931 Q14739,Q14108,O75844,P51798,Q13510,P04062,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,8,19,115,55,86,31 939,200,1890,19,2205,120,1894,86,31,2117,2923,1898,800,802,1232,586,1367,362,115,1924,1147,2643,2745,1483,1932,55,8,35,983,1075,548,2159,2700,411,346,1639,851,2187,1991,1996,1319 0.228081190180689,1.057240248022844,-0.2812183777015856,3.926946339483657,-0.4621081592112762,1.434245143990909,-0.2812183777015856,1.8491689704918812,3.6169723053440874,-0.4011890781327106,-3.598238387349531,-0.2812183777015856,0.33452611576463864,0.33452611576463864,0.06384250748914849,0.48964847025575964,0.007872098580347686,0.7361572254974664,1.473918375909616,-0.2812183777015856,0.11919997011538998,-0.8407704557687973,-1.0386067543300004,-0.04871252906513763,-0.2812183777015856,2.5014551385438826,4.712282471751374,3.4391717680711436,0.228081190180689,0.17394576765407171,0.5401492501085412,-0.4011890781327106,-0.906083163548422,0.688050566378247,0.7836800160884329,-0.10591263929674817,0.33452611576463864,-0.4011890781327106,-0.2812183777015856,-0.2812183777015856,0.06384250748914849 2937 Dysphagia 14 128 2.6302641333173926 0.0085318550909572 Q99496,Q14739,P07602,P20700,Q99720,Q14108,O15118,P15586,Q13510,Q9NR77,Q01105,P04062,P01889,P61916 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,35,3,133,7,8,75,20,55,57,123,86,120,62 1326,1434,942,75,1440,706,1661,269,1446,1664,2787,948,2832,1573,250,1669,2383,2205,120,86,1347,1454,3,2385,1675,2118,2211,391,20,1035,646,133,523,1688,965,2216,2833,1357,2534,359,1142,1471,2771,1245,875,1589,216,1249,1922,971,1814,1815,138,2478,2643,1254,2745,62,2400,595,733,2042,1062,123,736,2649,2046,2748,1490,2546,55,8,1065,669,1501,1829,35,1832,1163,899,1944,1728,2551,1731,1276,2844,1077,675,1955,678,1515,1517,1176,763,1967,1749,498,997,1970,96,2173,2501,7,687,1859,2901,1756,1978,556,1864,1763,57,1644,1006,424,2188,1010,2189,461,2845,1108,1873,1647,509,1649,1875,2622,1016 0.007872098580347686,-0.04871252906513763,0.228081190180689,1.9547430671585866,-0.04871252906513763,0.38683824468201267,-0.16372948749216756,0.8770244243066478,-0.04871252906513763,-0.16372948749216756,-1.1736688722168886,0.228081190180689,-1.3810415738737563,-0.10591263929674817,0.9228702829555585,-0.16372948749216756,-0.5858198190406446,-0.4621081592112762,1.434245143990909,1.8491689704918812,0.007872098580347686,-0.04871252906513763,5.131894866624145,-0.5858198190406446,-0.16372948749216756,-0.4011890781327106,-0.4621081592112762,0.688050566378247,3.887244197186541,0.17394576765407171,0.4385452506124256,1.3536292924938709,0.5401492501085412,-0.16372948749216756,0.228081190180689,-0.4621081592112762,-1.3810415738737563,0.007872098580347686,-0.7120374352425395,0.7361572254974664,0.11919997011538998,-0.04871252906513763,-1.1058199287517425,0.06384250748914849,0.2816075367943659,-0.10591263929674817,1.0129671489863166,0.06384250748914849,-0.2812183777015856,0.228081190180689,-0.22216432068703482,-0.22216432068703482,1.3126701679029467,-0.6486147893595557,-0.8407704557687973,0.06384250748914849,-1.0386067543300004,2.157214859958303,-0.5858198190406446,0.48964847025575964,0.38683824468201267,-0.34089288926430916,0.17394576765407171,1.434245143990909,0.38683824468201267,-0.8407704557687973,-0.34089288926430916,-1.0386067543300004,-0.04871252906513763,-0.7120374352425395,2.5014551385438826,4.712282471751374,0.17394576765407171,0.4385452506124256,-0.04871252906513763,-0.22216432068703482,3.4391717680711436,-0.22216432068703482,0.11919997011538998,0.2816075367943659,-0.2812183777015856,-0.16372948749216756,-0.7120374352425395,-0.16372948749216756,0.06384250748914849,-1.451444818165324,0.17394576765407171,0.4385452506124256,-0.2812183777015856,0.4385452506124256,-0.04871252906513763,-0.04871252906513763,0.11919997011538998,0.38683824468201267,-0.2812183777015856,-0.16372948749216756,0.5900489466309929,0.228081190180689,-0.2812183777015856,1.7404982072045598,-0.4011890781327106,-0.6486147893595557,4.758390219688548,0.4385452506124256,-0.22216432068703482,-2.0378507439803,-0.16372948749216756,-0.2812183777015856,0.5401492501085412,-0.22216432068703482,-0.16372948749216756,2.410780403978149,-0.10591263929674817,0.228081190180689,0.688050566378247,-0.4011890781327106,0.228081190180689,-0.4011890781327106,0.6393489264185823,-1.451444818165324,0.17394576765407171,-0.22216432068703482,-0.10591263929674817,0.5900489466309929,-0.10591263929674817,-0.22216432068703482,-0.7760889340064466,0.228081190180689 2937 Nonimmune hydrops fetalis 14 26 2.6215245487400405 0.0087537457647877 P46777,Q14739,P61353,P18077,P61313,P42766,P61254,P62847,Q9BT22,P62244,P10619,P04062,P39019,Q07020 Drugs and Diseases Human Phenotype Ontology msigdb_hp 440,35,252,522,396,137,481,139,316,482,58,86,333,537 1340,1789,86,1673,1792,58,522,333,137,440,969,2479,481,396,252,533,482,1705,139,2809,731,1707,537,35,316,1763 0.007872098580347686,-0.22216432068703482,1.8491689704918812,-0.16372948749216756,-0.22216432068703482,2.3177619175977977,0.5401492501085412,0.7836800160884329,1.3126701679029467,0.6393489264185823,0.228081190180689,-0.6486147893595557,0.5900489466309929,0.688050566378247,0.9228702829555585,0.5401492501085412,0.5900489466309929,-0.16372948749216756,1.3126701679029467,-1.2421547136861633,0.38683824468201267,-0.16372948749216756,0.5401492501085412,3.4391717680711436,0.8306316454399105,-0.16372948749216756 2937 Juvenile onset 8 38 2.620740812441189 0.0087738939282964 P16278,P54802,O15118,P38571,Q13510,O14773,Q9NR77,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 37,42,75,17,55,24,57,31 24,75,434,1671,1894,1576,31,1454,37,2214,587,2898,17,2471,2222,1477,2591,217,303,2808,115,42,1598,1262,2046,1716,55,1161,1066,2407,2921,915,774,502,1102,57,2512,2905 3.7652112572324823,1.9547430671585866,0.6393489264185823,-0.16372948749216756,-0.2812183777015856,-0.10591263929674817,3.6169723053440874,-0.04871252906513763,3.4162772870291325,-0.4621081592112762,0.48964847025575964,-2.0378507439803,3.9856208887046614,-0.6486147893595557,-0.4621081592112762,-0.04871252906513763,-0.7760889340064466,1.0129671489863166,0.8306316454399105,-1.2421547136861633,1.473918375909616,3.078582353860239,-0.10591263929674817,0.06384250748914849,-0.34089288926430916,-0.16372948749216756,2.5014551385438826,0.11919997011538998,0.17394576765407171,-0.5858198190406446,-3.510150275167924,0.2816075367943659,0.38683824468201267,0.5900489466309929,0.17394576765407171,2.410780403978149,-0.6486147893595557,-2.1909305126679395 2937 Late endosome 11 53 2.6188796707430058 0.0088219059790735 P07602,P13473,Q14108,P11717,O15118,Q9BUN8,P11279,P51790,Q9ULH0,P20645,Q8IV08 Localization GO Cellular component msigdb_gocc 3,36,8,44,75,149,48,49,183,152,63 2624,75,383,704,2304,3,1896,714,1457,48,44,36,1350,152,871,872,1142,875,1051,49,1052,972,2594,8,1382,405,406,63,1513,615,414,498,416,2174,149,999,2074,2760,1760,502,852,2188,697,2922,210,1312,183,2368,935,2672,2919,938,2711 -0.8407704557687973,1.9547430671585866,0.688050566378247,0.38683824468201267,-0.5236513396667263,5.131894866624145,-0.2812183777015856,0.38683824468201267,-0.04871252906513763,2.618889115071512,2.94951498403428,3.4162772870291325,0.007872098580347686,1.229406481355582,0.2816075367943659,0.2816075367943659,0.11919997011538998,0.2816075367943659,0.17394576765407171,2.618889115071512,0.17394576765407171,0.228081190180689,-0.7760889340064466,4.712282471751374,0.007872098580347686,0.688050566378247,0.688050566378247,2.157214859958303,-0.04871252906513763,0.48964847025575964,0.688050566378247,0.5900489466309929,0.688050566378247,-0.4011890781327106,1.2712655154383892,0.228081190180689,-0.34089288926430916,-1.0386067543300004,-0.16372948749216756,0.5900489466309929,0.33452611576463864,-0.4011890781327106,0.4385452506124256,-3.510150275167924,1.057240248022844,0.06384250748914849,1.1442885584140452,-0.5236513396667263,0.2816075367943659,-0.8407704557687973,-2.9956170913795845,0.2816075367943659,-0.906083163548422 2937 Action tremor 7 53 2.617903523815922 0.0088471814580828 P07602,P20700,Q99720,Q14108,O14773,Q9NR77,P15289 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,133,7,8,24,57,95 1434,24,942,1443,434,1446,2787,1668,1669,1576,1347,3,1675,95,1684,1794,2460,133,2634,1463,1241,359,1916,1593,971,1814,1815,596,1490,8,899,2835,157,2409,1949,2698,2921,911,2609,2173,7,1763,2762,57,1006,695,424,2188,1010,1873,1204,2622,1016 -0.04871252906513763,3.7652112572324823,0.228081190180689,-0.04871252906513763,0.6393489264185823,-0.04871252906513763,-1.1736688722168886,-0.16372948749216756,-0.16372948749216756,-0.10591263929674817,0.007872098580347686,5.131894866624145,-0.16372948749216756,1.7404982072045598,-0.16372948749216756,-0.22216432068703482,-0.6486147893595557,1.3536292924938709,-0.8407704557687973,-0.04871252906513763,0.06384250748914849,0.7361572254974664,-0.2812183777015856,-0.10591263929674817,0.228081190180689,-0.22216432068703482,-0.22216432068703482,0.48964847025575964,-0.04871252906513763,4.712282471751374,0.2816075367943659,-1.3810415738737563,1.229406481355582,-0.5858198190406446,-0.2812183777015856,-0.906083163548422,-3.510150275167924,0.2816075367943659,-0.7760889340064466,-0.4011890781327106,4.758390219688548,-0.16372948749216756,-1.0386067543300004,2.410780403978149,0.228081190180689,0.4385452506124256,0.688050566378247,-0.4011890781327106,0.228081190180689,-0.22216432068703482,0.11919997011538998,-0.7760889340064466,0.228081190180689 2937 Trans golgi network 20 53 2.6145911350978093 0.0089334324149628 Q969E2,Q96A57,O14828,Q8WWQ0,Q969M3,Q92538,P61006,O43795,P20645,O75122,Q5VYK3,P11717,Q86SZ2,P50570,P98194,Q9BTU6,Q4J6C6,P09496,P04062,O15127 Localization GO Cellular component msigdb_gocc 135,414,249,551,284,283,395,385,152,268,405,44,194,303,204,500,85,326,86,113 1563,249,113,2105,385,1118,268,2010,86,326,798,44,152,1905,2023,1796,1243,303,1919,1052,532,2541,395,1373,972,204,1062,823,2653,1725,85,2337,405,2491,194,551,283,135,284,414,2173,500,999,1408,2430,2434,2280,2088,933,1768,1770,935,2001 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2937 Fever 9 78 2.6056016794994163 0.0091713047590449 P07602,Q14739,P38571,P35610,Q13510,P51572,Q9NR77,P01889,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,35,17,53,55,122,57,120,31 942,1329,200,705,1445,1890,1787,796,2458,120,1672,2206,31,1127,3,2118,129,714,1033,799,800,1684,1794,1232,718,2466,804,586,53,2741,17,2471,1367,1477,1808,725,122,232,1054,2643,1598,594,2229,596,1932,2141,1716,739,55,1718,1161,35,1723,1267,603,1729,2245,2058,2753,408,548,2159,2499,915,916,1746,374,2827,2082,1102,57,2187,2188,1009,2845,2512,1319,382 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2937 Thickened skin 19 99 2.599361219715337 0.0093397435303794 Q9BTV4,O75844,Q15125,P04066,P06280,P51648,Q14739,P16278,P40855,P56589,P12955,Q9UBN7,Q9P265,P98194,P53634,P04062,P50402,Q06136,Q9H1A4 Drugs and Diseases Human Phenotype Ontology msigdb_hp 258,19,26,30,31,275,35,37,164,174,187,210,350,204,203,86,217,234,260 939,942,1022,2198,1657,1441,707,1024,2009,19,2897,1892,1343,1028,355,1671,1790,1894,86,30,1673,31,1127,1580,2459,187,521,2884,2911,37,957,1684,393,1794,2121,523,1688,1463,586,1038,2534,2469,1142,164,2770,658,2391,725,217,275,1482,2134,203,174,594,204,2594,1931,1932,484,234,823,337,2691,598,980,487,35,26,1833,1163,1836,1944,2054,1384,2339,2154,1735,1074,1519,1742,551,1178,1746,1967,1184,2856,258,260,1760,1639,2431,2669,2186,350,210,1996,2709,2295 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2937 Myoclonus 9 85 2.5982977517303896 0.0093687216804823 Q99496,P07602,O75503,P52788,Q14108,P50897,Q13510,O14773,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 96,3,4,70,8,22,55,24,86 1433,1434,24,1329,2107,4,212,1666,388,2013,711,297,1125,2458,86,1576,3,437,438,2460,961,2464,1137,2534,477,2741,1471,2127,875,1695,2538,1593,22,1249,70,1813,971,2643,1057,595,254,1062,123,1262,2649,538,55,668,8,669,1829,2337,1949,2698,2796,1955,2160,1082,995,1747,1527,1853,1854,1749,1401,997,96,2173,2901,1978,2507,1191,1763,2508,246,1544,929,1546,2188,1200,2289,2622,2919,1016,2295 -0.04871252906513763,-0.04871252906513763,3.7652112572324823,0.007872098580347686,-0.4011890781327106,4.878143286316388,1.0129671489863166,-0.16372948749216756,0.688050566378247,-0.34089288926430916,0.38683824468201267,0.8306316454399105,0.11919997011538998,-0.6486147893595557,1.8491689704918812,-0.10591263929674817,5.131894866624145,0.6393489264185823,0.6393489264185823,-0.6486147893595557,0.228081190180689,-0.6486147893595557,0.11919997011538998,-0.7120374352425395,0.5900489466309929,-1.0386067543300004,-0.04871252906513763,-0.4011890781327106,0.2816075367943659,-0.16372948749216756,-0.7120374352425395,-0.10591263929674817,3.8063874677803375,0.06384250748914849,2.057376685439682,-0.22216432068703482,0.228081190180689,-0.8407704557687973,0.17394576765407171,0.48964847025575964,0.9228702829555585,0.17394576765407171,1.434245143990909,0.06384250748914849,-0.8407704557687973,0.5401492501085412,2.5014551385438826,0.4385452506124256,4.712282471751374,0.4385452506124256,-0.22216432068703482,-0.5236513396667263,-0.2812183777015856,-0.906083163548422,-1.1736688722168886,-0.2812183777015856,-0.4011890781327106,0.17394576765407171,0.228081190180689,-0.16372948749216756,-0.04871252906513763,-0.22216432068703482,-0.22216432068703482,-0.16372948749216756,0.007872098580347686,0.228081190180689,1.7404982072045598,-0.4011890781327106,-2.0378507439803,-0.2812183777015856,-0.6486147893595557,0.11919997011538998,-0.16372948749216756,-0.6486147893595557,0.9681807864168185,-0.04871252906513763,0.2816075367943659,-0.04871252906513763,-0.4011890781327106,0.11919997011538998,-0.4621081592112762,-0.7760889340064466,-2.9956170913795845,0.228081190180689,-0.4621081592112762 2937 Ascites 7 26 2.596715922900155 0.009411972894628 Q14739,Q14108,O95342,O15118,P38571,Q13510,P61916 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,8,69,75,17,55,62 75,2902,2450,1886,69,86,714,956,2213,1586,17,2037,62,2400,1823,2139,442,443,2749,55,8,35,603,1746,2509,2905 1.9547430671585866,-2.114065123664798,-0.6486147893595557,-0.2812183777015856,2.057376685439682,1.8491689704918812,0.38683824468201267,0.228081190180689,-0.4621081592112762,-0.10591263929674817,3.9856208887046614,-0.34089288926430916,2.157214859958303,-0.5858198190406446,-0.22216432068703482,-0.4011890781327106,0.6393489264185823,0.6393489264185823,-1.0386067543300004,2.5014551385438826,4.712282471751374,3.4391717680711436,0.48964847025575964,-0.16372948749216756,-0.6486147893595557,-2.1909305126679395 2937 Lipid biosynthesis 19 48 2.593350256810428 0.0095045918807192 Q8N5B7,Q8WVX9,Q15125,Q16850,P11498,Q14739,P14324,Q9UBM7,Q9H7Z7,O00763,Q6UWP7,Q15392,Q9P035,O95674,P37268,O75845,Q53GQ0,Q96N66,Q13085 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 679,410,26,27,390,35,521,38,181,292,192,71,630,323,332,212,489,242,485 1324,292,2447,212,323,795,2457,390,521,332,2314,2391,2034,1367,1701,1709,1932,485,1936,827,35,26,1833,1614,71,2054,27,489,192,2253,679,2256,410,1394,837,242,2734,1978,1406,2275,1002,181,2081,696,630,38,2763,1558 0.007872098580347686,0.8306316454399105,-0.6486147893595557,1.0129671489863166,0.7836800160884329,0.33452611576463864,-0.6486147893595557,0.688050566378247,0.5401492501085412,0.7836800160884329,-0.5236513396667263,-0.5858198190406446,-0.34089288926430916,0.007872098580347686,-0.16372948749216756,-0.16372948749216756,-0.2812183777015856,0.5900489466309929,-0.2812183777015856,0.33452611576463864,3.4391717680711436,3.7024803541208557,-0.22216432068703482,-0.10591263929674817,2.057376685439682,-0.34089288926430916,3.7024803541208557,0.5900489466309929,1.101010637080487,-0.4621081592112762,0.4385452506124256,-0.4621081592112762,0.688050566378247,0.007872098580347686,0.33452611576463864,0.9681807864168185,-0.9720282133639213,-0.2812183777015856,0.007872098580347686,-0.4621081592112762,0.228081190180689,1.1442885584140452,-0.34089288926430916,0.4385452506124256,0.48964847025575964,3.4162772870291325,-1.0386067543300004,-0.04871252906513763 2937 Metalloprotease 6 38 2.5882500226758527 0.0096464934840194 Q9UIQ6,Q7Z2K6,P02786,O75844,Q5JRX3,P42892 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 2,98,41,19,157,25 1562,466,2625,468,790,2627,19,2013,41,2529,187,1682,1233,1796,2029,25,813,2395,663,538,2327,2055,157,1623,98,1514,1285,553,2422,496,1530,2733,687,773,627,2187,2,1016 -0.10591263929674817,0.5900489466309929,-0.8407704557687973,0.5900489466309929,0.33452611576463864,-0.8407704557687973,3.926946339483657,-0.34089288926430916,3.1288971739076072,-0.7120374352425395,1.101010637080487,-0.16372948749216756,0.06384250748914849,-0.22216432068703482,-0.34089288926430916,3.744431287238993,0.33452611576463864,-0.5858198190406446,0.4385452506124256,0.5401492501085412,-0.5236513396667263,-0.34089288926430916,1.229406481355582,-0.10591263929674817,1.7035577277228184,-0.04871252906513763,0.06384250748914849,0.5401492501085412,-0.5858198190406446,0.5900489466309929,-0.04871252906513763,-0.9720282133639213,0.4385452506124256,0.38683824468201267,0.48964847025575964,-0.4011890781327106,5.198840694526526,0.228081190180689 2937 Organic acid transmembrane transporter activity 7 20 2.586740767478411 0.009688845437179 P53985,Q15758,O95342,P08183,P08195,Q9Y619,O14975 Functions GO Molecular function msigdb_gomf 276,310,69,13,144,127,266 1437,266,1570,69,574,13,144,807,1922,276,1261,310,2339,2561,1974,317,923,1200,1767,127 -0.04871252906513763,0.8770244243066478,-0.10591263929674817,2.057376685439682,0.48964847025575964,4.192232038011874,1.2712655154383892,0.33452611576463864,-0.2812183777015856,0.8770244243066478,0.06384250748914849,0.8306316454399105,-0.5236513396667263,-0.7120374352425395,-0.2812183777015856,0.8306316454399105,0.2816075367943659,0.11919997011538998,-0.16372948749216756,1.434245143990909 2937 Premature birth 7 45 2.5798085613888877 0.0098855099687276 Q9UBM7,O95342,P40855,O43676,O75844,P51798,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 38,69,164,46,19,115,86 1205,46,1334,1119,1663,19,1340,69,355,1894,86,1454,2462,1907,872,1142,333,164,2536,2317,1920,115,1053,174,1702,1598,2594,2749,1935,1829,1269,1944,2811,2339,1517,1958,915,2270,1193,1004,1544,2088,38,1993,632 0.06384250748914849,2.8427159818750036,0.007872098580347686,0.11919997011538998,-0.16372948749216756,3.926946339483657,0.007872098580347686,2.057376685439682,0.7361572254974664,-0.2812183777015856,1.8491689704918812,-0.04871252906513763,-0.6486147893595557,-0.2812183777015856,0.2816075367943659,0.11919997011538998,0.7836800160884329,1.1870839548927827,-0.7120374352425395,-0.5236513396667263,-0.2812183777015856,1.473918375909616,0.17394576765407171,1.1442885584140452,-0.16372948749216756,-0.10591263929674817,-0.7760889340064466,-1.0386067543300004,-0.2812183777015856,-0.22216432068703482,0.06384250748914849,-0.2812183777015856,-1.2421547136861633,-0.5236513396667263,-0.04871252906513763,-0.2812183777015856,0.2816075367943659,-0.4621081592112762,0.11919997011538998,0.228081190180689,-0.04871252906513763,-0.34089288926430916,3.4162772870291325,-0.2812183777015856,0.48964847025575964 2937 Abnormal systemic arterial morphology 41 135 2.569042353501608 0.0101979992651632 P07602,P10253,P61353,Q92890,P42766,P55011,P62847,Q9Y296,P06865,P38571,O75844,Q9Y4A5,O95394,Q07020,Q99622,P16278,P18077,P21359,Q9UBM7,P61313,Q9H7D7,Q13510,P10619,P07686,P61916,Q96L58,P46777,Q7LGA3,Q6ZXV5,O15118,O15460,O75175,Q6NUK1,P04062,P39019,O75845,Q9UGU0,Q9Y4L1,P62244,P01889,P61254 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,129,252,411,137,138,139,425,16,17,19,431,388,537,315,37,522,523,38,396,319,55,58,61,62,196,440,344,205,75,200,201,220,86,333,212,507,511,482,120,481 1561,75,1332,200,945,2902,2450,1886,1118,201,1663,1569,1783,1890,19,212,388,2679,1790,120,1894,86,1454,16,3,61,1792,129,58,714,1459,37,1684,522,646,1794,1905,523,1688,802,1232,963,872,1356,1237,2637,2684,657,2314,2869,17,333,1473,137,875,2536,440,969,2390,1917,1813,2924,1147,1815,138,1148,2643,2479,481,396,252,62,2229,533,2772,482,1705,139,2809,731,1707,1150,596,2594,1931,2140,1490,537,975,2691,55,2240,1265,897,1503,603,2551,1510,220,2058,2251,205,344,2844,1172,1515,1281,1742,2700,1746,411,196,1968,2856,1970,315,687,846,319,1539,2509,1766,2188,38,1991,507,1108,2287,425,1996,1319,431,511,2802,1878 -0.10591263929674817,1.9547430671585866,0.007872098580347686,1.057240248022844,0.228081190180689,-2.114065123664798,-0.6486147893595557,-0.2812183777015856,0.11919997011538998,1.057240248022844,-0.16372948749216756,-0.10591263929674817,-0.22216432068703482,-0.2812183777015856,3.926946339483657,1.0129671489863166,0.688050566378247,-0.906083163548422,-0.22216432068703482,1.434245143990909,-0.2812183777015856,1.8491689704918812,-0.04871252906513763,4.024165938684547,5.131894866624145,2.1898966319486153,-0.22216432068703482,1.3941514953495935,2.3177619175977977,0.38683824468201267,-0.04871252906513763,3.4162772870291325,-0.16372948749216756,0.5401492501085412,0.4385452506124256,-0.22216432068703482,-0.2812183777015856,0.5401492501085412,-0.16372948749216756,0.33452611576463864,0.06384250748914849,0.228081190180689,0.2816075367943659,0.007872098580347686,0.06384250748914849,-0.8407704557687973,-0.906083163548422,0.4385452506124256,-0.5236513396667263,-1.6665070292939557,3.9856208887046614,0.7836800160884329,-0.04871252906513763,1.3126701679029467,0.2816075367943659,-0.7120374352425395,0.6393489264185823,0.228081190180689,-0.5858198190406446,-0.2812183777015856,-0.22216432068703482,-3.598238387349531,0.11919997011538998,-0.22216432068703482,1.3126701679029467,0.11919997011538998,-0.8407704557687973,-0.6486147893595557,0.5900489466309929,0.688050566378247,0.9228702829555585,2.157214859958303,-0.4621081592112762,0.5401492501085412,-1.1058199287517425,0.5900489466309929,-0.16372948749216756,1.3126701679029467,-1.2421547136861633,0.38683824468201267,-0.16372948749216756,0.11919997011538998,0.48964847025575964,-0.7760889340064466,-0.2812183777015856,-0.4011890781327106,-0.04871252906513763,0.5401492501085412,0.228081190180689,-0.906083163548422,2.5014551385438826,-0.4621081592112762,0.06384250748914849,0.2816075367943659,-0.04871252906513763,0.48964847025575964,-0.7120374352425395,-0.04871252906513763,1.0129671489863166,-0.34089288926430916,-0.4621081592112762,1.057240248022844,0.7836800160884329,-1.451444818165324,0.11919997011538998,-0.04871252906513763,0.06384250748914849,-0.16372948749216756,-0.906083163548422,-0.16372948749216756,0.688050566378247,1.101010637080487,-0.2812183777015856,-1.5224894117754426,-0.2812183777015856,0.8306316454399105,0.4385452506124256,0.33452611576463864,0.8306316454399105,-0.04871252906513763,-0.6486147893595557,-0.16372948749216756,-0.4011890781327106,3.4162772870291325,-0.2812183777015856,0.5900489466309929,0.17394576765407171,-0.4621081592112762,0.688050566378247,-0.2812183777015856,0.06384250748914849,0.688050566378247,0.5900489466309929,-1.1736688722168886,-0.22216432068703482 2937 Contractures of the joints of the upper limbs 14 68 2.5627354944533844 0.0103851132497634 Q9BTV4,Q9BZI7,P50402,Q15392,Q99720,Q7LGA3,Q96AY3,P41227,O75844,P42892,Q9Y619,P37268,Q96L58,Q9NR77 Drugs and Diseases Human Phenotype Ontology msigdb_hp 258,125,217,71,7,344,105,231,19,25,127,332,196,57 1563,1778,942,1441,2713,1118,2112,19,1573,1894,1454,1352,1684,1905,1232,718,1907,872,1468,359,332,231,529,25,2536,2034,2474,217,1249,1815,1702,1598,2870,1931,598,980,1829,983,2692,2775,71,2406,1510,2811,2058,2699,344,1519,915,1178,1180,2166,105,196,1968,2270,1970,1753,7,1403,258,125,2431,1004,57,1431,127,513 -0.10591263929674817,-0.22216432068703482,0.228081190180689,-0.04871252906513763,-0.9720282133639213,0.11919997011538998,-0.4011890781327106,3.926946339483657,-0.10591263929674817,-0.2812183777015856,-0.04871252906513763,0.007872098580347686,-0.16372948749216756,-0.2812183777015856,0.06384250748914849,0.38683824468201267,-0.2812183777015856,0.2816075367943659,-0.04871252906513763,0.7361572254974664,0.7836800160884329,0.9681807864168185,0.5401492501085412,3.744431287238993,-0.7120374352425395,-0.34089288926430916,-0.6486147893595557,1.0129671489863166,0.06384250748914849,-0.22216432068703482,-0.16372948749216756,-0.10591263929674817,-1.6665070292939557,-0.2812183777015856,0.48964847025575964,0.228081190180689,-0.22216432068703482,0.228081190180689,-0.906083163548422,-1.1058199287517425,2.057376685439682,-0.5858198190406446,-0.04871252906513763,-1.2421547136861633,-0.34089288926430916,-0.906083163548422,0.7836800160884329,-0.04871252906513763,0.2816075367943659,0.11919997011538998,0.11919997011538998,-0.4011890781327106,1.628562285011634,1.101010637080487,-0.2812183777015856,-0.4621081592112762,-0.2812183777015856,-0.16372948749216756,4.758390219688548,0.007872098580347686,0.9228702829555585,1.434245143990909,-0.5858198190406446,0.228081190180689,2.410780403978149,0.007872098580347686,1.434245143990909,0.5900489466309929 2937 Abnormal oral mucosa morphology 13 58 2.5589227707225137 0.0104997064185483 P49257,O75845,Q9UM00,Q14739,P16278,P20700,Q9UBM7,Q14108,Q15392,Q9Y4U1,P53634,P04062,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 272,212,172,35,37,133,38,8,71,248,203,86,120 1020,707,1445,2009,212,2383,1892,120,86,1127,714,2911,37,133,961,2684,2471,2390,272,1367,203,594,1150,2232,2791,1932,2792,484,1154,2691,1718,8,35,1723,1503,1163,71,986,1510,2058,1735,2753,914,2159,1085,1181,1184,2067,319,2186,2187,38,2287,172,2709,511,2802,248 0.17394576765407171,0.38683824468201267,-0.04871252906513763,-0.34089288926430916,1.0129671489863166,-0.5858198190406446,-0.2812183777015856,1.434245143990909,1.8491689704918812,0.11919997011538998,0.38683824468201267,-2.425443155290095,3.4162772870291325,1.3536292924938709,0.228081190180689,-0.906083163548422,-0.6486147893595557,-0.5858198190406446,0.8770244243066478,0.007872098580347686,1.057240248022844,0.48964847025575964,0.11919997011538998,-0.4621081592112762,-1.1736688722168886,-0.2812183777015856,-1.1736688722168886,0.5900489466309929,0.11919997011538998,-0.906083163548422,-0.16372948749216756,4.712282471751374,3.4391717680711436,-0.16372948749216756,-0.04871252906513763,0.11919997011538998,2.057376685439682,0.228081190180689,-0.04871252906513763,-0.34089288926430916,-0.16372948749216756,-1.0386067543300004,0.2816075367943659,-0.4011890781327106,0.17394576765407171,0.11919997011538998,0.11919997011538998,-0.34089288926430916,0.8306316454399105,-0.4011890781327106,-0.4011890781327106,3.4162772870291325,-0.4621081592112762,1.1870839548927827,-0.906083163548422,0.5900489466309929,-1.1736688722168886,0.9681807864168185 2937 Negative regulation of response to external stimulus 17 43 2.5579908427733016 0.0105278864531972 O43657,Q9UMX5,P04439,O94813,O14786,Q92890,Q96BN8,P55011,Q9Y5A9,Q9Y4E8,Q07021,Q9NX58,P80303,P04062,P01889,P39019,O75122 Processes and pathways GO Biological process msigdb_gobp 33,65,128,68,97,411,374,138,321,380,444,182,50,86,120,333,268 97,1329,33,268,1569,68,120,86,128,800,1461,2312,586,2388,1239,1140,333,2685,138,2643,881,2893,50,2401,1932,444,1941,2330,2873,746,2060,2163,411,374,918,498,1404,182,2089,65,1319,380,321 1.7035577277228184,0.007872098580347686,3.4619133058097864,0.8770244243066478,-0.10591263929674817,2.057376685439682,1.434245143990909,1.8491689704918812,1.3941514953495935,0.33452611576463864,-0.04871252906513763,-0.5236513396667263,0.48964847025575964,-0.5858198190406446,0.06384250748914849,0.11919997011538998,0.7836800160884329,-0.906083163548422,1.3126701679029467,-0.8407704557687973,0.2816075367943659,-1.96228632337628,2.618889115071512,-0.5858198190406446,-0.2812183777015856,0.6393489264185823,-0.2812183777015856,-0.5236513396667263,-1.6665070292939557,0.38683824468201267,-0.34089288926430916,-0.4011890781327106,0.688050566378247,0.7361572254974664,0.2816075367943659,0.5900489466309929,0.007872098580347686,1.1442885584140452,-0.34089288926430916,2.124237547972303,0.06384250748914849,0.7361572254974664,0.8306316454399105 2937 Coated vesicle membrane 15 53 2.55470483608599 0.0106277877166924 P49257,Q8N511,Q15286,P49755,P04439,O94979,Q14108,P02786,P24390,P11717,Q9NVZ3,Q15363,Q13190,P01889,P20645 Localization GO Cellular component msigdb_gocc 272,131,256,274,128,250,8,41,74,44,320,339,306,120,152 1020,1207,2102,2579,2105,1335,517,1219,2114,250,951,1670,120,41,128,326,798,2923,1457,44,716,152,74,1141,1591,272,274,1052,2134,1924,2899,1147,1925,1601,818,1062,306,8,256,339,745,131,1747,1866,320,1311,2618,1551,1316,2293,432,2623,636 0.17394576765407171,0.06384250748914849,-0.4011890781327106,-0.7760889340064466,-0.4011890781327106,0.007872098580347686,0.5401492501085412,0.06384250748914849,-0.4011890781327106,0.9228702829555585,0.228081190180689,-0.16372948749216756,1.434245143990909,3.1288971739076072,1.3941514953495935,0.7836800160884329,0.33452611576463864,-3.598238387349531,-0.04871252906513763,2.94951498403428,0.38683824468201267,1.229406481355582,1.9892736116862897,0.11919997011538998,-0.10591263929674817,0.8770244243066478,0.8770244243066478,0.17394576765407171,-0.4011890781327106,-0.2812183777015856,-2.0378507439803,0.11919997011538998,-0.2812183777015856,-0.10591263929674817,0.33452611576463864,0.17394576765407171,0.8306316454399105,4.712282471751374,0.9228702829555585,0.7836800160884329,0.38683824468201267,1.3941514953495935,-0.16372948749216756,-0.22216432068703482,0.8306316454399105,0.06384250748914849,-0.7760889340064466,-0.04871252906513763,0.06384250748914849,-0.4621081592112762,0.688050566378247,-0.7760889340064466,0.48964847025575964 2937 Lipid metabolic process 46 239 2.5520971769710905 0.0107076648857711 Q9HB40,P07602,Q8WTV0,Q8NCC3,P06865,P38571,Q99829,O75844,Q9BQE5,P50897,O14773,Q15125,Q16850,O14975,P04066,P06280,P51648,Q14739,P53985,P16278,Q9UBM7,P07099,Q9BT22,Q9H7Z7,P35610,O00763,Q13510,Q8NBX0,P07686,P61916,Q86UY6,Q6UWP7,Q15392,O95342,Q99805,O15118,P30536,Q9H490,P04062,P15289,O75845,Q96N66,Q99735,P68402,O60762,Q06136 Processes and pathways GO Biological process msigdb_gobp 0,3,14,15,16,17,286,19,23,22,24,26,27,266,30,31,275,35,276,37,38,39,316,181,53,292,55,60,61,62,195,192,71,69,207,75,82,91,86,95,212,242,243,106,228,234 465,1206,1324,637,1563,292,2447,24,1209,266,75,1438,2376,1022,2198,1211,789,1333,1443,862,2379,2380,228,517,1024,708,1337,2821,2010,1447,19,212,948,1573,69,1343,2203,323,2014,795,796,2457,86,30,2680,1895,298,2208,31,389,16,39,3,61,357,1583,1584,799,390,2210,1034,2212,800,521,2120,1230,95,2387,37,1352,2213,1901,1461,584,802,2023,2634,2462,718,2466,2215,2026,653,1466,2636,1237,82,2469,2861,53,2741,332,2849,2314,2869,17,1244,2535,588,2771,2472,810,2473,2536,2391,2034,480,1367,2744,877,22,1051,1249,275,2037,2133,1701,276,2540,2687,1599,62,106,886,1375,1709,1932,821,2649,2140,234,538,2928,485,1936,55,2750,827,2146,35,1382,1502,1832,1724,2824,26,1833,1614,71,1615,1067,2054,1505,2873,2333,1068,27,2695,2599,404,489,2487,406,1511,2339,904,192,1733,195,1078,2253,2921,1081,911,679,2932,1516,2255,60,15,2256,2257,14,410,1394,837,761,763,453,554,242,2562,1751,2067,416,2070,2501,243,207,286,2734,23,316,500,1978,1406,2356,2275,2177,1000,1002,91,1300,181,2277,0,2081,2181,927,2573,2088,696,2188,630,2616,38,377,1107,1425,2763,1011,2090,1109,2441,1873,509,2098,1558,513 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2937 Abnormality of epiphysis morphology 9 50 2.547603809999083 0.0108465576407361 Q14739,P16278,Q9UBM7,Q9Y619,P40855,P51798,Q9H4A3,P56589,Q15125 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,37,38,127,164,115,160,174,26 1324,1563,1438,1118,1663,1452,575,355,2015,714,37,1352,1905,964,1468,527,2869,2315,164,115,2640,174,594,2042,2140,1156,2691,35,983,26,2054,986,449,2251,344,1735,1852,346,196,2856,1403,1538,160,1986,851,38,1649,1996,2709,127 0.007872098580347686,-0.10591263929674817,-0.04871252906513763,0.11919997011538998,-0.16372948749216756,-0.04871252906513763,0.48964847025575964,0.7361572254974664,-0.34089288926430916,0.38683824468201267,3.4162772870291325,0.007872098580347686,-0.2812183777015856,0.228081190180689,-0.04871252906513763,0.5401492501085412,-1.6665070292939557,-0.5236513396667263,1.1870839548927827,1.473918375909616,-0.8407704557687973,1.1442885584140452,0.48964847025575964,-0.34089288926430916,-0.4011890781327106,0.11919997011538998,-0.906083163548422,3.4391717680711436,0.228081190180689,3.7024803541208557,-0.34089288926430916,0.228081190180689,0.6393489264185823,-0.4621081592112762,0.7836800160884329,-0.16372948749216756,-0.22216432068703482,0.7836800160884329,1.101010637080487,-1.5224894117754426,0.007872098580347686,-0.04871252906513763,1.229406481355582,-0.2812183777015856,0.33452611576463864,3.4162772870291325,-0.10591263929674817,-0.2812183777015856,-0.906083163548422,1.434245143990909 2937 Disproportionate short limb short stature 7 19 2.546388059020233 0.0108844114681181 Q14739,Q15392,Q9UBM7,Q7LGA3,Q9UBN7,Q32P28,Q15125 Drugs and Diseases Human Phenotype Ontology msigdb_hp 35,71,38,344,210,80,26 1324,1438,1663,2299,714,2531,588,1591,337,35,26,71,80,1510,344,1852,2856,38,210 0.007872098580347686,-0.04871252906513763,-0.16372948749216756,-0.5236513396667263,0.38683824468201267,-0.7120374352425395,0.48964847025575964,-0.10591263929674817,0.7836800160884329,3.4391717680711436,3.7024803541208557,2.057376685439682,1.919885894471246,-0.04871252906513763,0.7836800160884329,-0.22216432068703482,-1.5224894117754426,3.4162772870291325,1.057240248022844 2937 Metabolism of lipids 35 169 2.539781610186243 0.0110921707059528 P07602,O43772,Q8NCC3,P06865,Q99829,P50897,Q15125,Q16850,O14975,P06280,P51648,Q14739,P16278,Q9UBM7,Q9H7Z7,P35610,O00763,Q13510,P10619,P07686,Q8IV08,Q6UWP7,Q15392,O95342,P30536,P04062,P15289,O75845,Q96N66,Q9NQZ5,Q16881,Q15165,P36873,Q06136,Q9Y2W1 Processes and pathways Reactome Pathways msigdb_reactome 3,12,15,16,286,22,26,27,266,31,275,35,37,38,181,53,292,55,58,61,63,192,71,69,82,86,95,212,242,246,111,110,230,234,265 565,1324,637,1563,292,2447,266,1438,2376,1022,2198,1443,12,862,2804,2379,1218,1120,1337,2201,2821,212,1669,69,1343,951,2203,323,795,796,86,298,2208,31,16,3,61,357,1583,58,1584,521,1230,95,2387,37,1132,801,2022,716,2807,2023,2634,2462,718,2466,2636,82,2861,53,2741,230,332,2869,1244,2535,2771,2472,1474,1476,2391,2034,480,1367,2744,877,22,275,2037,1922,1701,1147,2540,2226,972,2876,2772,1374,595,1709,1932,234,538,2894,485,55,2750,827,2146,35,1382,1502,1830,1832,26,1833,110,1614,71,745,1067,2054,1068,27,111,404,489,2487,192,1733,2699,910,63,2253,2921,1081,679,2932,1516,15,2256,410,1394,837,554,1851,242,2562,1089,416,998,286,2734,1533,500,1978,1406,2356,1000,181,2181,246,927,1644,2088,696,2188,630,2616,38,1011,1109,2091,265,1775,1877,2623,1558,513 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2937 vesicles 42 145 2.537238961806855 0.0111730658957491 Q15286,P04439,Q969E2,Q8IXU6,O94979,Q93050,Q969V3,Q92538,Q969M3,O60826,Q9Y678,Q15125,O15400,O75165,P49257,P49755,Q9UM00,P53985,P13473,Q15758,P02786,P11279,Q969T9,O60493,P56589,P50570,Q15392,P11166,Q8N6T3,Q15363,O95674,Q9BTU6,Q9Y3E0,O96005,Q96QK1,P09496,Q5VW38,O15258,O75845,O15127,P51798,Q06136 Localization OpenCell Localization opencell_localization 256,128,135,6,250,413,285,283,284,143,432,26,383,269,272,274,172,276,36,310,41,48,454,293,174,303,71,437,345,339,323,500,226,324,498,326,88,322,212,113,115,234 1325,1207,1326,1563,2102,2447,1437,2373,2579,113,1564,1210,861,322,1022,383,1660,862,293,570,143,269,1219,212,250,1669,1343,323,324,2457,41,128,1895,1791,326,798,437,48,799,36,1132,1133,1686,2022,716,961,2023,807,2469,1360,2127,588,2771,2221,2391,272,274,812,303,1051,115,532,1924,276,1147,1055,1925,174,2320,1373,972,1703,730,1149,1256,1601,1059,2773,818,1062,234,538,2906,1936,2482,1158,2750,26,256,339,71,745,2054,310,984,1384,88,1620,1169,1074,6,2417,345,2256,615,283,413,135,284,454,285,1086,1966,2562,498,2857,1532,1404,500,2074,1000,1098,502,2428,1411,1101,852,2616,2922,1311,1312,2782,1551,2574,172,1316,702,2368,935,2672,634,226,2444,432,1558 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2937 Neuromuscular process 6 20 2.536600443497143 0.0111934627013836 P10253,O60934,O75844,O14773,P04062,P07686 Processes and pathways GO Biological process msigdb_gobp 129,186,19,24,86,61 24,186,2010,19,86,61,129,588,810,1695,1249,2593,1065,1725,1276,1075,2497,678,498,315 3.7652112572324823,1.101010637080487,-0.34089288926430916,3.926946339483657,1.8491689704918812,2.1898966319486153,1.3941514953495935,0.48964847025575964,0.33452611576463864,-0.16372948749216756,0.06384250748914849,-0.7760889340064466,0.17394576765407171,-0.16372948749216756,0.06384250748914849,0.17394576765407171,-0.6486147893595557,0.4385452506124256,0.5900489466309929,0.8306316454399105 2937 Coarse facial features 6 64 2.533013807868848 0.0113086498130672 P16278,P54802,P15586,P10619,P04066,P06280 Drugs and Diseases Human Phenotype Ontology msigdb_hp 37,42,20,58,30,31 939,1020,1563,1021,575,30,31,61,645,58,20,37,1684,1794,961,1905,523,1463,872,2684,1142,721,2314,2471,231,1590,726,2640,42,2229,1150,666,596,2594,484,1490,1935,598,980,897,1503,1948,344,1174,1285,410,993,1294,1399,1968,2067,1970,315,2569,1864,319,1539,1986,2287,2093,509,2672,2802,2711 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2937 Monosaccharide binding 9 27 2.514423112302365 0.0119227296989246 P49257,O75503,Q16851,P11717,O15460,Q32P28,P35613,O60762,Q5KU26 Functions GO Molecular function msigdb_gomf 272,4,168,44,200,80,145,228,28 1778,200,1118,228,4,2010,1672,712,578,2117,799,44,520,1681,2717,2681,145,657,272,1920,2539,2545,1931,336,168,80,28 -0.22216432068703482,1.057240248022844,0.11919997011538998,0.9681807864168185,4.878143286316388,-0.34089288926430916,-0.16372948749216756,0.38683824468201267,0.48964847025575964,-0.4011890781327106,0.33452611576463864,2.94951498403428,0.5401492501085412,-0.16372948749216756,-0.9720282133639213,-0.906083163548422,1.2712655154383892,0.4385452506124256,0.8770244243066478,-0.2812183777015856,-0.7120374352425395,-0.7120374352425395,-0.2812183777015856,0.7836800160884329,1.1870839548927827,1.919885894471246,3.681306413452911 2937 Abnormality of extrapyramidal motor function 20 71 2.511537312415377 0.0120206577577521 Q00577,P07602,Q99720,P06865,O75165,P12235,P16278,P35610,O96008,P07686,P11166,Q04446,Q96QK1,Q6DKK2,P04062,O14949,Q99496,Q9Y4U1,Q9H0B6,P35637 Drugs and Diseases Human Phenotype Ontology msigdb_hp 254,3,7,16,269,391,37,53,297,61,437,443,498,492,86,94,96,248,107,359 94,269,1336,2787,1890,297,2205,86,1454,16,3,61,643,437,1034,391,37,1035,1684,1794,2460,2466,2029,2684,1043,53,359,875,1249,971,1814,2478,2643,2822,1150,2138,254,443,736,1490,2546,1065,1503,1386,492,1276,1746,1400,498,997,96,2609,2173,7,2564,2507,107,1302,2508,2914,2188,1010,2845,2287,1873,509,2622,1319,2802,248,1016 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2937 Multicellular organismal homeostasis 10 59 2.5107053003504767 0.0120490237404384 Q9UIQ6,P78310,P42785,Q01433,P55011,P02786,P38571,P51790,O14773,P04062 Processes and pathways GO Biological process msigdb_gobp 2,188,5,103,138,41,17,49,24,86 292,24,1439,1658,790,2451,201,2832,1668,41,86,797,2017,437,1230,583,1132,393,523,718,2929,2861,1360,17,2471,1244,1588,5,2744,1051,49,138,188,2401,103,736,2140,2749,255,1715,485,1936,669,1163,1164,1836,1068,1276,2256,765,1401,2569,1539,2181,2185,1548,2,2370,2099 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2937 Abnormal bone structure 27 164 2.509753086505805 0.0120815605868274 P07602,Q14108,O75844,Q9H4A3,Q15125,P06280,Q14739,P16278,Q9UBM7,P40855,P54802,Q13510,P56589,Q96L58,P52788,Q15392,P12955,Q9UBN7,Q32P28,P53634,Q9H490,Q6NUK1,P04062,P48735,Q96AY3,P51798,Q9Y619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 3,8,19,160,26,31,35,37,38,164,42,55,174,196,70,71,187,210,80,203,91,220,86,216,105,115,127 1324,939,1778,1437,942,467,1438,1332,1441,789,2902,2450,1886,1118,707,1663,2009,2112,1569,2299,19,212,948,1787,1452,1892,1027,575,355,796,2015,1790,1894,86,2206,298,2208,1673,31,712,1127,1674,3,2527,714,391,187,2868,37,2213,1132,1684,1794,1905,523,1688,1462,1586,2531,2929,1463,1907,1038,1468,1360,2684,1141,527,2314,2869,1363,2471,2885,164,1473,2034,216,970,2037,115,1052,70,203,2899,971,42,1815,2478,174,1254,1598,594,2229,1707,1150,1823,1605,2594,1931,484,1607,1494,1156,540,55,8,981,35,983,1612,2775,1503,2148,26,1163,71,745,603,2054,1165,80,986,2337,220,1731,407,1735,452,1280,551,1746,1181,453,105,2268,1852,346,1184,196,997,260,1982,1538,91,160,1540,693,2509,2182,851,1766,2186,2188,38,210,2287,1996,2896,2709,430,2802,2905,2295,127 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2937 er 24 85 2.50455935018822 0.0122604033605873 Q969V3,Q969M3,Q9Y487,Q15125,Q16850,P49755,Q9UM00,Q14739,Q13190,Q15392,Q9NQC3,Q9P2W9,Q15363,O95674,Q9Y3E0,O96005,O75915,O75845,Q96N66,Q5J8M3,Q15041,Q96GC9,Q06136,P51572 Localization OpenCell Localization opencell_localization 285,284,430,26,27,274,172,35,306,71,208,351,339,323,226,324,213,212,242,239,369,118,234,122 1325,2447,861,1022,2198,1212,517,1219,212,213,1669,1343,323,324,796,2457,519,641,1455,2585,959,1689,805,1363,591,2391,2034,274,1919,122,2478,2720,594,1373,883,2773,885,1603,735,234,401,1608,306,35,2852,369,26,339,71,2054,985,27,239,2339,2495,2498,679,914,2256,2907,1850,615,1288,284,2664,285,1294,118,242,1533,1406,1000,1411,208,1866,927,2616,351,172,1204,226,430,1320,2623,1558 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2937 Cutaneous photosensitivity 6 26 2.504322199418247 0.0122686251918167 P12955,O60934,Q9UBM7,Q14108,Q13426,Q06136 Drugs and Diseases Human Phenotype Ontology msigdb_hp 187,186,38,8,337,234 186,1572,1027,1576,1673,2211,187,521,1684,1794,2463,963,1463,1361,332,725,2225,1932,234,1712,337,8,1833,1746,38,1319 1.101010637080487,-0.10591263929674817,0.17394576765407171,-0.10591263929674817,-0.16372948749216756,-0.4621081592112762,1.101010637080487,0.5401492501085412,-0.16372948749216756,-0.22216432068703482,-0.6486147893595557,0.228081190180689,-0.04871252906513763,0.007872098580347686,0.7836800160884329,0.38683824468201267,-0.4621081592112762,-0.2812183777015856,0.9681807864168185,-0.16372948749216756,0.7836800160884329,4.712282471751374,-0.22216432068703482,-0.16372948749216756,3.4162772870291325,0.06384250748914849 2937 Hepatic failure 10 45 2.5036227218047484 0.0122929039908814 P40855,O43772,O15118,O15460,P38571,Q13510,P56589,Q9Y619,P04062,P01889 Drugs and Diseases Human Phenotype Ontology msigdb_hp 164,12,75,200,17,55,174,127,86,120 1559,75,200,12,707,1783,212,1892,355,120,86,1127,2017,1581,1676,2213,2463,718,653,2589,17,164,1244,1803,1590,877,971,2540,174,2139,443,538,2691,55,2333,1068,449,750,2172,2277,2186,1420,633,2905,127 -0.10591263929674817,1.9547430671585866,1.057240248022844,4.2103839880354075,0.38683824468201267,-0.22216432068703482,1.0129671489863166,-0.2812183777015856,0.7361572254974664,1.434245143990909,1.8491689704918812,0.11919997011538998,-0.34089288926430916,-0.10591263929674817,-0.16372948749216756,-0.4621081592112762,-0.6486147893595557,0.38683824468201267,0.4385452506124256,-0.7760889340064466,3.9856208887046614,1.1870839548927827,0.06384250748914849,-0.22216432068703482,-0.10591263929674817,0.2816075367943659,0.228081190180689,-0.7120374352425395,1.1442885584140452,-0.4011890781327106,0.6393489264185823,0.5401492501085412,-0.906083163548422,2.5014551385438826,-0.5236513396667263,0.17394576765407171,0.6393489264185823,0.38683824468201267,-0.4011890781327106,-0.4621081592112762,-0.4011890781327106,0.007872098580347686,0.48964847025575964,-2.1909305126679395,1.434245143990909 2937 Biological process involved in interaction with host 11 47 2.4914612714856443 0.0127218835757467 P78310,Q15758,O14786,Q14108,P02786,Q8WTV0,O15118,P11279,P35613,P08195,Q9BTY2 Processes and pathways GO Biological process msigdb_gobp 188,310,97,8,41,14,75,48,145,144,52 2519,97,75,293,2383,41,797,952,1674,144,1456,1678,48,390,1351,1682,1460,1586,2470,145,659,1696,1051,188,1491,824,2144,2404,8,2145,310,2407,611,909,1958,14,615,2731,2169,2174,52,852,697,2616,2922,2368,2290 -0.7120374352425395,1.7035577277228184,1.9547430671585866,0.8306316454399105,-0.5858198190406446,3.1288971739076072,0.33452611576463864,0.228081190180689,-0.16372948749216756,1.2712655154383892,-0.04871252906513763,-0.16372948749216756,2.618889115071512,0.688050566378247,0.007872098580347686,-0.16372948749216756,-0.04871252906513763,-0.10591263929674817,-0.6486147893595557,1.2712655154383892,0.4385452506124256,-0.16372948749216756,0.17394576765407171,1.101010637080487,-0.04871252906513763,0.33452611576463864,-0.4011890781327106,-0.5858198190406446,4.712282471751374,-0.4011890781327106,0.8306316454399105,-0.5858198190406446,0.48964847025575964,0.2816075367943659,-0.2812183777015856,4.192232038011874,0.48964847025575964,-0.9720282133639213,-0.4011890781327106,-0.4011890781327106,2.618889115071512,0.33452611576463864,0.4385452506124256,-0.7760889340064466,-3.510150275167924,-0.5236513396667263,-0.4621081592112762 2937