term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size cytoplasmic 178 383 6.094721238391275 1.0962831971707692e-09 O00443,O15144,O60610,P33981,P48729,P49327,Q9UQB8,P62280,Q99460,P09496,Q13442,P61353,Q92530,P49721,P53367,Q92538,Q96P70,Q9H4A3,Q05682,P60228,P35579,P20339,P62826,Q12979,P20290,Q8TEX9,Q9H0B6,Q9Y3A5,P42766,P61923,P28070,O43592,Q13614,Q7Z417,P46379,Q8WUM4,P14174,Q15382,Q9H8V3,Q13177,Q13283,P26641,O00231,P09132,O75821,P52732,P11802,O43242,Q8WXX5,Q99615,P26038,Q9Y371,Q9H2G2,P35998,O43237,Q15008,P51665,P37108,Q14008,O15397,Q0VDF9,P62258,Q96A49,P18206,P62861,Q16543,O75165,Q9H2J4,Q9UNM6,Q13200,P46976,P20618,P62993,Q9NT62,P31689,Q9Y496,Q99436,O95373,Q68EM7,P07900,Q9NZB2,Q9Y6G9,P42345,Q5VYK3,Q9UL46,P06493,Q9Y678,P61221,Q15418,P13693,P15104,P24941,P31150,O76094,P50579,P53396,O94979,P53621,O60749,P55884,Q14247,Q99543,Q16513,Q14997,Q13409,P50570,Q92900,P08238,O60921,Q9BT73,Q969T9,P62906,P17612,P55036,O00410,O43414,Q14204,O60524,P0DMV9,P11142,P27348,P26373,P28072,P28074,P27361,P30260,Q13561,O00429,Q04917,Q06323,O15498,Q96EK5,Q16181,Q9NR46,Q9UBB4,P41240,Q9Y3P9,P62269,P17980,O95456,O15145,Q2NL82,Q8N6T3,P14635,P49720,P62820,P42566,P43487,P31751,P28066,P14324,P31946,Q92696,Q9UI12,Q14444,Q15019,Q86UK7,Q92973,Q9BQ70,Q9Y547,Q9H7E9,Q9NVA2,Q9NVZ3,Q9UN86,O60884,P55010,P31948,O75832,O95747,P22314,O95433,P17812,P33176,O75122,Q96GA3,Q00610,P27708,P63104 Localization OpenCell Localization opencell_localization 486,487,488,499,502,503,18,506,549,535,46,542,578,50,51,579,580,57,59,564,63,563,565,567,85,623,92,632,95,96,105,587,110,117,114,661,122,132,667,139,653,642,149,639,153,648,158,165,710,711,176,722,189,686,182,201,198,688,697,195,695,692,212,209,225,228,220,761,767,745,235,735,236,257,736,259,253,244,251,245,275,280,265,270,811,263,813,267,292,771,772,775,777,769,780,782,284,783,282,784,786,316,841,840,311,308,850,306,304,854,336,835,824,834,814,817,332,818,822,823,827,325,326,327,828,829,895,345,889,890,346,351,373,907,908,370,914,887,362,360,860,399,401,873,884,395,882,388,878,876,383,385,957,971,428,429,952,432,435,976,963,967,968,973,412,421,418,919,921,924,444,447,473,471,520,508,496,507 1968,1041,149,1106,1969,814,2014,345,486,1766,1168,1236,1919,1831,487,860,1582,195,346,1832,1354,182,165,817,587,2395,1633,818,2216,488,1635,2020,282,412,304,471,220,2814,1584,153,919,769,284,1359,244,444,360,921,1050,1637,1412,1176,1116,1360,263,2173,1239,983,245,306,639,535,1837,822,1529,1839,823,1118,158,1782,1241,771,986,122,383,1841,987,873,772,1978,824,447,362,209,1642,1532,1478,85,1362,563,735,924,1533,775,1182,2877,1183,926,1184,1418,176,325,642,827,828,496,876,105,326,327,1981,1247,829,1845,1929,777,2440,736,878,385,418,473,499,1120,63,686,1310,2682,1846,2082,1311,688,1367,992,1061,370,2029,1646,265,1368,882,1312,95,388,1480,114,1189,1593,235,1787,1250,502,2133,503,1191,1193,884,50,1251,1195,308,780,1426,1252,1065,1371,1789,1598,198,1855,996,2031,648,1428,1484,51,782,783,1599,2227,1486,421,834,1934,784,564,2229,1066,1431,2759,1254,1935,1542,1067,267,542,931,96,1126,1255,1374,1857,692,1936,887,506,395,565,225,835,1545,236,507,2511,1793,2362,1260,1651,1937,508,1070,1071,1323,1072,2444,889,59,890,1074,695,2090,1199,567,1002,139,745,653,1603,1437,311,46,1605,895,1005,110,1861,1201,1078,697,332,786,2367,428,1606,1693,840,1737,201,429,2272,1332,1554,132,292,2644,1010,1203,373,2093,841,1865,1011,228,2611,399,270,251,1495,1805,2046,1140,1384,1207,117,1209,952,401,2190,623,661,2764,1146,710,578,579,1453,957,850,432,2891,336,212,2151,2425,351,1562,520,1021,1506,1151,580,2855,1344,253,1751,549,316,711,1389,2379,1347,1456,1665,435,2107,2380,854,2525,1816,1874,92,1460,1030,189,761,1219,57,963,667,1912,907,257,967,968,2733,275,1397,2205,1285,908,1286,1877,1101,971,1288,2388,1574,1878,811,2594,1672,1575,973,1167,767,18,1469,2628,1232,2347,722,632,1827,2060,914,259,1881,2873,976,2391,1105,813,280 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2937 Nervous system development 102 206 5.037226267766401 4.723263202466038e-07 O15144,Q9NR77,P60866,P62081,P62280,Q99460,Q16850,P09496,P61353,P48556,Q92530,P49721,Q96P70,Q15370,P35579,P05387,O00487,P35241,P39019,P62899,P42766,P61927,P62829,P28070,P35580,P62495,O14786,Q7Z406,P46782,Q8N8S7,P15311,P61254,Q13177,O00231,P46783,P62917,P62277,O43242,Q04637,P26038,Q9Y490,P35998,P08865,Q9UQ16,P18077,Q15008,P51665,P62861,Q9UNM6,Q9Y3U8,Q13885,Q13200,P20618,P62993,P19174,Q9BZI7,P46779,Q99436,P62241,P46778,P07900,Q9UL46,P59998,Q15418,P11940,P83881,Q14997,Q01082,P50570,P08238,P04350,P62906,P17612,P55036,P11142,P26373,P28072,P27361,P28074,Q9HAU5,Q06323,P62847,P35268,P62269,P62910,P35080,P17980,O15145,P49720,P18124,P28066,P23396,P39023,P46776,Q13617,Q13813,P62750,Q00169,P62701,P62191,O75122,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 487,13,504,505,506,549,31,535,542,539,578,50,580,572,63,562,560,76,82,83,95,604,607,105,113,606,118,119,599,660,134,136,139,149,155,650,649,165,171,176,723,686,680,194,682,201,198,225,767,243,747,745,735,236,234,255,738,253,743,737,245,811,266,292,770,289,840,310,308,306,305,835,824,834,823,325,326,828,327,355,890,372,367,887,888,366,362,860,884,874,876,384,387,389,425,426,423,455,454,477,471,508 149,1106,560,2302,118,1353,487,860,165,2395,471,919,1114,1526,1678,1302,1411,1412,2502,305,2603,562,1638,2261,983,245,306,1414,680,535,1837,823,770,1641,1978,134,1530,824,362,682,874,1477,234,1478,735,384,1364,1245,1183,926,1184,1418,176,325,828,1419,876,105,326,327,1247,2355,1644,1931,366,76,367,63,113,686,1846,1311,1786,82,387,1645,95,1480,389,1189,737,738,1482,599,155,1593,1314,539,927,884,50,1251,308,1933,1539,198,1855,1599,834,266,2229,504,1431,1254,2360,1067,1197,136,1856,1650,542,1432,931,604,505,477,1374,743,1489,1857,1936,1433,887,1689,649,506,1127,1128,606,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,236,1546,2761,2548,1731,1600,289,1651,455,1937,508,310,932,1691,1071,1549,171,2579,890,1131,2708,2365,139,745,425,426,747,938,840,201,2092,572,292,2093,1011,1898,31,119,660,2916,578,1612,958,2485,1748,580,1344,253,549,1457,1568,1153,255,355,13,1963,811,767,194,243,723,2166 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2937 Signaling by robo receptors 77 137 4.451810925316552 8.514912646973016e-06 P60866,P62081,P62280,Q99460,P61353,P48556,Q92530,P49721,Q15370,P05387,O00487,P39019,P62899,P42766,P61927,P62829,P28070,P62495,O14786,P46782,Q8N8S7,P61254,Q13177,O00231,P46783,P62917,P62277,O43242,Q04637,P35998,P08865,P18077,Q15008,P51665,P62861,Q9UNM6,Q9Y3U8,Q13200,P20618,Q9BZI7,P46779,Q99436,P62241,P46778,Q9UL46,P11940,P83881,Q14997,P62906,P17612,P55036,P26373,P28072,P28074,Q9HAU5,Q06323,P62847,P35268,P62269,P62910,P35080,P17980,P49720,P18124,P28066,P23396,P39023,P46776,Q13617,P62750,O75832,P25787,P49207,P61586,P62701,P62191,O75122 Processes and pathways Reactome Pathways msigdb_reactome 504,505,506,549,542,539,578,50,572,562,560,82,83,95,604,607,105,606,118,599,660,136,139,149,155,650,649,165,171,686,680,682,201,198,225,767,243,745,735,255,738,253,743,737,811,770,289,840,835,824,834,325,326,327,355,890,372,367,887,888,366,362,884,874,876,384,387,389,425,423,919,926,927,931,454,477,471 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2937 Plasma membrane region 44 160 4.309334707084807 1.6374638947436182e-05 O15144,Q9BPW8,P08183,P15311,Q8WTV0,Q9Y639,P40855,Q9UQB8,P23396,Q9Y6M7,O95342,Q99720,Q15019,P53985,P09601,O75935,P26038,P35613,Q01082,P50570,P08238,Q9Y4G8,P35579,Q9UQ16,Q9H4M9,P35241,Q9UBN7,P06744,Q96A49,Q9UPN3,Q07157,P78310,Q9BTU6,Q96EY1,O75122,O00429,Q16181,Q13614,Q92974,P19174,P35580,O14786,Q9UJU6,Q00610 Localization GO Cellular component msigdb_gocc 487,2,8,134,10,408,264,18,384,148,22,23,429,161,34,283,176,420,310,308,306,61,63,194,340,76,80,324,212,485,479,478,354,352,471,345,373,110,519,234,113,118,120,508 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2937 Regulation of expression of slits and robos 66 123 4.259984355884613 2.0444121251461667e-05 P46778,P49720,P61254,P18124,P60866,P62081,P62280,Q9UL46,P23396,P39023,Q99460,O00231,P46776,P11940,P46783,P62917,P62277,O43242,Q13617,P83881,Q04637,P62750,P61353,P48556,Q92530,P49721,Q14997,Q15370,P35998,P05387,O00487,P08865,P18077,P62906,P55036,P62701,Q15008,P51665,P39019,P62899,P26373,P28072,P28074,P62191,P62861,Q9HAU5,P42766,P61927,P62829,P28070,Q06323,Q9UNM6,Q9Y3U8,P62847,Q13200,P17980,P20618,P62495,Q9BZI7,P46782,P35268,P62269,P46779,Q99436,P62910,P62241 Processes and pathways Reactome Pathways msigdb_reactome 737,884,136,874,504,505,506,811,384,387,549,149,389,770,155,650,649,165,425,289,171,423,542,539,578,50,840,572,686,562,560,680,682,835,834,454,201,198,82,83,325,326,327,477,225,355,95,604,607,105,890,767,243,372,745,362,735,606,255,599,367,887,738,253,888,743 149,1106,560,1353,165,919,1114,2603,562,1638,1414,680,770,1978,1530,362,682,874,1477,735,384,1245,1183,926,1184,1418,325,1419,876,105,326,327,1644,1931,367,686,1311,1786,82,387,1645,95,1480,389,1189,737,738,1482,599,155,1314,539,927,884,50,1933,198,834,504,1431,1197,136,1856,1650,542,1432,604,505,477,1374,743,1489,1857,1936,1433,887,1689,649,506,1127,1128,606,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,171,890,1131,2708,745,425,840,201,572,2916,578,253,549,255,355,811,767,243,2166 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2937 S phase 56 94 4.176463219460753 2.960765901383056e-05 P33991,P49720,Q9UQE7,P31751,P28066,Q9UJX3,Q9UL46,P27694,Q99460,O00231,P49642,P28340,Q7Z5K2,Q9Y2S7,P24941,Q29RF7,P33992,P33993,P11802,O43242,Q14566,Q14683,P51530,P48556,Q92530,P49721,P35251,Q14997,O75832,P35998,P25787,Q9BRT9,O00487,P49643,Q07864,P55036,Q15008,P51665,P35244,P49736,P28072,P28074,P30260,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y248,Q16763,P17980,Q99436,Q8N3U4 Processes and pathways Reactome Pathways msigdb_reactome 246,884,279,878,876,810,811,875,549,149,390,643,951,557,775,547,778,537,158,165,290,788,781,539,578,50,419,840,919,686,926,193,560,928,839,834,201,198,450,690,326,327,829,477,826,89,105,890,767,745,735,530,126,362,253,659 149,1106,560,1353,165,1113,2170,919,1639,158,1782,362,2439,735,775,826,1183,926,1184,1418,875,876,105,326,327,643,829,878,246,778,537,450,2131,1534,419,686,1122,2507,2222,1480,539,1595,390,928,884,50,690,1251,1851,781,198,834,89,1431,1856,477,1374,1127,1259,890,839,1602,745,935,1006,290,788,840,201,126,547,951,659,578,2425,253,549,1215,193,1025,1571,1821,1624,1467,2388,810,1760,1574,811,767,279,530,557,2392 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2937 Predicted membrane proteins 83 473 4.051330445055034 5.092722417776585e-05 Q567V2,O43772,Q9NS69,P08183,O60830,Q8WTV0,Q8IXU6,Q8NCC3,Q9NR77,Q5VW38,Q5BJF2,Q9H6V9,Q06136,Q8NBX0,O95342,Q99720,P20645,Q99595,Q6N075,Q16850,P09601,Q15629,P30519,O75964,Q9BQE5,O43676,Q14739,P24390,P56589,Q9NZ01,Q9Y282,Q14108,P13073,Q92544,Q15125,P42892,O75844,O43657,P37268,Q16799,O14786,Q9Y266,Q8WY22,P43307,Q9NZQ3,P42858,Q9Y6M7,O43169,P35610,P46783,Q9BTX1,P53985,Q9BTW9,Q7Z7H5,Q07065,O60637,O15118,Q9UDW1,Q8N511,Q15392,Q9H061,Q96A26,Q86UP2,O75165,O00566,P04439,O15173,Q9HD45,Q6ZNB6,Q9UIQ6,O60271,O95563,Q70HW3,O14828,Q8TBA6,Q96NB2,Q86XL3,Q969V3,Q9BT22,Q6UW02,P06744,O15127,P50402 Functions Protein Atlas Protein class protein_atlas_protein_class 3,4,7,8,9,10,11,12,13,15,16,19,20,21,22,23,25,27,30,31,34,39,41,42,43,44,48,67,70,72,81,79,77,91,94,106,102,101,109,111,118,121,127,130,142,144,148,150,154,155,156,161,163,162,178,174,173,190,186,202,207,206,229,220,218,232,231,274,271,277,261,262,294,281,314,338,334,337,339,333,324,320,330 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2937 Receptor 15 33 3.964551353449973 7.353411592281311e-05 P04150,P24390,Q9NS69,Q8WTV0,Q99623,Q14108,Q14739,Q9Y2W1,P06493,O15173,P35613,O15118,Q99720,O14786,P20645 Functions Protein Atlas Molecular function protein_atlas_molecular_function 221,67,7,10,377,79,48,379,263,231,420,173,23,118,25 915,118,173,231,732,221,2261,263,2071,680,822,2633,1178,1242,25,67,1928,420,478,1895,1003,79,48,1334,1271,10,851,377,23,7,1290,379,1520 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P10412,P49720,Q13177,P31751,P49327,Q9UL46,P31946,Q99460,O00231,O43242,Q13813,P35611,P48556,P08670,Q92530,P09429,P49721,Q14997,P35998,Q14126,O00487,P55036,Q15008,P51665,P62258,P27348,P27361,P28072,P26583,P28074,P30419,P62191,Q07157,O00429,Q04917,P28070,Q06323,Q9UNM6,Q13200,P20618,P40763,Q9UJU6,P17980,Q99436,Q13546,P63104 Processes and pathways Reactome Pathways msigdb_reactome 869,884,139,878,503,811,385,549,149,165,426,287,539,414,578,415,50,840,686,570,560,834,201,198,692,827,828,326,86,327,830,477,479,345,889,105,890,767,745,735,598,120,362,253,510,507 149,1106,1298,345,560,1353,165,1883,919,980,2025,2123,414,415,869,1179,2076,1844,362,735,1307,1182,1183,926,1184,1418,86,827,828,876,105,326,327,1247,830,878,385,2130,287,686,598,1312,1480,539,503,884,50,1124,198,2031,834,1431,1856,1255,477,1374,692,1127,507,2511,889,890,1939,479,139,745,510,426,570,1693,840,201,1202,578,253,549,1393,120,1915,811,767,1518 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2937 Mitotic g1 phase and g1 s transition 49 75 3.895443433189986 9.801923697527748e-05 P33991,P14635,P49720,P31751,P28066,P27694,Q9UL46,P06493,P31350,P49642,Q99460,O00231,P24941,P33992,P33993,P11802,Q14566,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,P49643,O00487,Q07864,P55036,Q15008,P51665,Q13309,P04818,P35244,P49736,P28072,P28074,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,P00374,Q99436,Q13200,P20618,P17980,Q13616,P30153 Processes and pathways Reactome Pathways msigdb_reactome 246,873,884,878,876,875,811,263,498,390,549,149,775,778,537,158,290,165,539,578,50,919,686,926,928,560,839,834,201,198,935,445,450,690,326,327,477,826,89,105,890,767,103,253,745,735,362,1006,990 149,1106,560,1353,165,1113,919,103,1056,445,263,1639,2124,158,1782,873,362,735,775,826,1183,926,1184,1418,875,876,105,326,327,990,1060,498,878,246,778,537,450,686,1480,539,390,928,884,50,690,1851,198,834,89,1431,1856,477,1374,1127,1258,1259,1000,890,839,1602,745,935,2609,1006,290,201,578,253,549,1215,1821,1467,811,767,2392 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2937 Abc family proteins mediated transport 33 48 3.832988254323672 0.0001265960002974 P08183,P49720,P40855,P28066,Q9UL46,O75027,Q99460,O00231,Q8NE71,P20042,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P56589,P55036,Q15008,P51665,P28072,P28074,P62191,P05198,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 8,884,264,876,811,636,549,149,299,773,165,539,578,50,840,919,686,560,70,834,201,198,326,327,477,594,105,890,767,745,735,362,253 149,1106,560,1353,165,636,919,2068,594,8,362,773,735,1183,926,1184,1418,876,105,326,327,1308,686,264,1480,539,884,50,198,834,1934,70,1431,1856,477,1374,1127,890,745,840,201,299,578,253,549,2009,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.5683656165997513,0.35698364577547,-0.4575872142200032,0.6027831121744145,4.383977831042348,0.8702695242261951,0.463737560425262,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.1367560507410777,0.5337207971688037,1.0307485270519672,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,-0.33327939055474815,1.9809980490909074,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.9990456262708737,0.6369761233848037,1.0622595380909912,0.6709474376181863,-0.3743938386878874,0.463737560425262,0.49884576098804173 2937 Dna replication pre initiation 39 61 3.806838057548823 0.0001407548465881 P33991,P49720,P28066,P27694,Q9UL46,P49642,Q99460,O00231,P24941,P33992,P33993,Q14566,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,Q07864,P55036,Q15008,P51665,P35244,P49736,P28072,P28074,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 246,884,876,875,811,390,549,149,775,778,537,290,165,539,578,50,840,919,686,926,560,839,834,201,198,450,690,326,327,477,826,89,105,890,767,745,735,362,253 149,1106,560,1353,165,1113,1635,919,1639,1888,362,735,775,826,1183,926,1184,1418,875,876,105,326,327,246,778,537,450,686,1480,539,390,928,884,50,690,198,2031,834,89,1431,1856,477,1374,1127,1690,890,839,745,290,1693,840,201,578,253,549,1215,1821,1467,811,767,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,-0.09305436959858496,0.35698364577547,-0.09305436959858496,-0.29248013870191797,0.8702695242261951,0.49884576098804173,0.463737560425262,0.428393191730484,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,1.0622595380909912,0.463737560425262,0.6709474376181863,0.7715583169098631,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.8375726207273704,0.35698364577547,0.3928095936133701,2.237423692928971,0.5337207971688037,1.1864283685836194,-0.4158281796670899,0.428393191730484,1.8207460887469624,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,-0.13234464502495924,0.3928095936133701,0.428393191730484,0.49884576098804173,0.9990456262708737,-0.13234464502495924,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.2111917997668451,-0.21180894066884262,0.0612563185418274,0.463737560425262,0.49884576098804173,-0.7152427522665485 2937 Regulation of cytoskeleton organization 43 123 3.798826191908049 0.0001453829978526 O15144,P46940,P15311,Q13177,Q14019,P37198,P42345,P16949,Q9UQB8,P23396,P59998,Q9BTW9,Q9Y5K6,Q6UVJ0,Q13813,Q08722,P35611,P53367,Q86VI3,Q01082,P04350,Q8TD16,P35241,Q14204,Q9UBN7,P53384,Q14203,Q9UHV9,Q07157,Q13045,O75122,Q15555,P12270,P62993,Q92974,P52565,P35080,O14786,Q02790,Q9UJU6,Q9NUQ9,Q00610,Q68EM7 Processes and pathways GO Biological process msigdb_gobp 487,131,134,139,140,386,265,143,18,384,266,163,440,293,426,424,287,51,313,310,305,205,76,332,80,331,211,484,479,226,471,348,104,236,519,371,366,118,509,120,128,508,251 118,487,860,816,2395,488,1972,471,2599,1114,1680,305,1976,983,822,104,2604,134,143,1180,2026,384,1182,828,1247,1309,366,76,287,1310,2682,386,2356,265,1064,645,131,2226,1787,600,1251,1852,371,1196,1484,51,331,1318,266,2759,1254,1319,601,931,236,2606,2511,2707,1733,1937,508,1796,310,509,1895,479,424,1379,2090,226,1002,139,2318,545,426,697,140,211,332,786,1863,348,1010,2093,2447,2040,251,293,2046,1698,313,205,661,2764,1706,958,519,755,1505,1957,1750,853,1348,163,667,1757,128,1963,718,80,1100,1399,484,120,2887,18,1470,1232,2347,440,1105,1577,1037 1.5705949318057502,0.704699791414857,0.3928095936133701,0.428393191730484,-0.759418488288081,0.704699791414857,-0.3743938386878874,0.7382358716884349,-1.0323962561974658,0.24801958368154803,-0.13234464502495924,0.9671485853633185,-0.3743938386878874,0.32091216739564127,0.428393191730484,1.6832758718136789,-1.0323962561974658,1.484439279959394,1.4261935465788533,0.2111917997668451,-0.4158281796670899,0.8375726207273704,0.2111917997668451,0.428393191730484,0.17410512476192191,0.1367560507410777,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.1367560507410777,-1.1742638113510904,0.8375726207273704,-0.7152427522665485,1.0307485270519672,0.28459191556669194,0.5683656165997513,1.5133178288044788,-0.5848621144923504,-0.21180894066884262,0.6027831121744145,0.17410512476192191,-0.2519914877556342,0.8702695242261951,0.2111917997668451,0.02309828334687722,2.237423692928971,0.9350551147231273,0.1367560507410777,1.0307485270519672,-1.3694172456596465,0.17410512476192191,0.1367560507410777,0.6027831121744145,0.35698364577547,1.0935808714347506,-1.0323962561974658,-0.8941728675715074,-1.222394988641525,-0.1719280959561597,-0.33327939055474815,0.704699791414857,-0.21180894066884262,0.9671485853633185,0.704699791414857,-0.29248013870191797,0.7382358716884349,0.8046697182564764,0.09914099907683403,-0.4575872142200032,1.1247147016520551,0.32091216739564127,1.455398437788666,-0.6714285051358926,0.6709474376181863,0.8046697182564764,0.5337207971688037,1.455398437788666,1.155663166669387,0.9350551147231273,0.463737560425262,-0.2519914877556342,0.9027628846125711,0.32091216739564127,-0.4575872142200032,-0.8039614683338043,-0.4158281796670899,1.0622595380909912,0.9990456262708737,-0.4158281796670899,-0.13234464502495924,0.9671485853633185,1.1864283685836194,0.5683656165997513,-1.3694172456596465,-0.13234464502495924,0.35698364577547,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.33327939055474815,-0.1719280959561597,0.428393191730484,0.1367560507410777,1.33757659471794,0.5683656165997513,-0.1719280959561597,1.5420358124097335,-0.33327939055474815,0.5337207971688037,1.901497527876068,0.28459191556669194,0.09914099907683403,0.7382358716884349,1.5705949318057502,-2.0009314909515403,3.7962488360202657,0.0612563185418274,0.2111917997668451,-0.6714285051358926,0.8046697182564764,0.28459191556669194,-0.015336908887356353,0.32091216739564127 2937 Programmed cell death 49 90 3.7890685051524966 0.0001512132146139 P07900,P10412,P49720,Q13177,P63104,P31751,P49327,Q9UL46,P31946,Q99460,O00231,O43242,Q13813,P35611,P48556,P08670,Q92530,P09429,P49721,Q14997,P35998,Q14126,O00487,P55036,Q15008,P51665,P62258,P27348,P27361,P28072,P26583,P28074,P30419,P62191,Q07157,Q16543,O00429,Q04917,P28070,Q06323,Q9UNM6,Q13200,P20618,P40763,Q9UJU6,P17980,Q99436,Q13546,Q8WUM4 Processes and pathways Reactome Pathways msigdb_reactome 245,869,884,139,507,878,503,811,385,549,149,165,426,287,539,414,578,415,50,840,686,570,560,834,201,198,692,827,828,326,86,327,830,477,479,228,345,889,105,890,767,745,735,598,120,362,253,510,661 149,1106,1298,345,560,1353,1581,165,1883,919,2657,980,2025,2123,245,414,415,869,1179,2076,1844,362,735,1307,1182,1183,926,1184,1418,86,827,828,876,105,326,327,1247,830,878,385,2130,287,686,598,1312,1480,539,503,884,50,1124,198,2031,834,1431,1856,1255,477,1374,692,1127,507,2511,889,890,1939,479,139,745,510,426,570,1329,1693,840,201,1202,228,661,2764,578,253,549,1393,120,1915,811,1102,767,1518 1.3968228224013606,0.24801958368154803,0.1367560507410777,0.9027628846125711,0.6369761233848037,0.09914099907683403,-0.05405313922784484,1.3076973767692464,-0.29248013870191797,0.35698364577547,-1.1265583700744997,0.32091216739564127,-0.4158281796670899,-0.4996758503153541,1.0622595380909912,0.8046697182564764,0.8046697182564764,0.3928095936133701,0.2111917997668451,-0.4575872142200032,-0.2519914877556342,0.8702695242261951,0.49884576098804173,0.1367560507410777,0.2111917997668451,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,1.8478045517497095,0.428393191730484,0.428393191730484,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.17410512476192191,0.428393191730484,0.3928095936133701,0.8375726207273704,-0.4996758503153541,0.9990456262708737,0.5337207971688037,0.6027831121744145,0.1367560507410777,0.02309828334687722,0.6709474376181863,0.704699791414857,0.3928095936133701,2.237423692928971,0.24801958368154803,1.1864283685836194,-0.4158281796670899,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.17410512476192191,0.7382358716884349,0.09914099907683403,0.5337207971688037,0.24801958368154803,0.704699791414857,-0.8941728675715074,0.3928095936133701,0.3928095936133701,-0.33327939055474815,0.7382358716884349,1.455398437788666,0.49884576098804173,0.704699791414857,0.8046697182564764,0.6369761233848037,0.1367560507410777,-0.13234464502495924,0.428393191730484,1.1864283685836194,0.2111917997668451,1.1247147016520551,0.5683656165997513,-1.3694172456596465,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.09914099907683403,1.5705949318057502,-0.29248013870191797,0.463737560425262,0.28459191556669194,0.49884576098804173,0.02309828334687722 2937 Eukaryotic translation initiation 51 102 3.788212115732151 0.0001517352794757 P46778,P61254,P60866,P62081,P62280,Q9UI10,P23396,P39023,P46776,O75821,P11940,P46783,P62917,P62277,P20042,P83881,P55884,Q04637,P62750,P61353,Q14152,P55010,P60228,O60841,P05387,P08865,Q9Y262,P18077,P62906,P62701,P39019,P62899,P26373,P62861,Q15056,P42766,P61927,P23588,P05198,Q13144,P62829,Q9Y3U8,P62847,O75822,P35268,P62269,P46782,P62910,P46779,O15372,P62241 Processes and pathways Reactome Pathways msigdb_reactome 737,136,504,505,506,809,384,387,389,153,770,155,650,649,773,289,784,171,423,542,180,421,564,303,562,680,467,682,835,454,82,83,325,225,227,95,604,364,594,893,607,243,372,729,367,887,599,888,738,862,743 1521,1042,862,303,153,729,594,2603,562,1638,1778,1414,680,770,1530,682,874,1477,773,384,364,1245,325,1419,1644,1931,367,1311,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,994,1933,421,784,2826,564,1066,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,171,1131,893,1437,180,939,1079,227,1140,1032,1877,809,467,243 -0.015336908887356353,0.28459191556669194,0.3928095936133701,0.9671485853633185,1.3672844525092513,0.49884576098804173,0.6027831121744145,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,-0.21180894066884262,0.0612563185418274,0.5337207971688037,0.463737560425262,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.463737560425262,0.8375726207273704,0.8702695242261951,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,0.32091216739564127,-0.33327939055474815,0.8046697182564764,0.463737560425262,-1.623692476299974,0.6369761233848037,0.28459191556669194,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,1.3076973767692464,0.24801958368154803,0.3928095936133701,0.0612563185418274,1.2776448956782354,0.35698364577547,0.28459191556669194,1.1247147016520551,0.24801958368154803,0.32091216739564127,-0.2519914877556342,0.463737560425262,0.7715583169098631,1.0935808714347506 2937 Auf1 hnrnp d0 binds and destabilizes mrna 29 41 3.784083666765685 0.0001542759226131 P49720,P28066,Q9UL46,O00231,Q99460,P11940,O43242,Q04637,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P11142,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,770,165,171,539,578,50,840,919,686,560,834,201,198,823,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,823,770,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,171,890,745,1862,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.428393191730484,0.463737560425262,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,1.3076973767692464,0.3928095936133701,0.49884576098804173,-0.2519914877556342,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Cellular response to hypoxia 28 39 3.749162364748301 0.0001774261921734 P49720,P28066,Q9UL46,O00231,Q99460,O43242,Q13617,P48556,Q92530,P49721,Q14997,Q15370,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,425,539,578,50,840,572,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,425,840,201,572,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.8046697182564764,0.428393191730484,1.1864283685836194,0.6369761233848037,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Perinuclear region of cytoplasm 35 161 3.720851927536296 0.0001985518370148 P07900,Q99627,P15311,Q9UIQ6,Q13177,Q9H7Z7,P42858,O60271,O75821,P20645,Q01105,P09601,O94979,O75935,Q07065,P26038,O15118,P50570,Q9H2G2,P08238,Q9Y4G8,Q58FF6,Q9UQ16,Q9H4M9,Q9UBN7,Q96A49,P26583,Q99700,Q15056,Q9HAU5,O60763,O00429,P42892,Q13614,P39687 Localization GO Cellular component msigdb_gocc 245,133,134,277,139,141,144,261,153,25,28,34,284,283,178,176,173,308,189,306,61,66,194,340,80,212,86,353,227,355,219,345,106,110,247 1352,345,1108,1767,1831,1109,173,1406,726,1471,978,261,2216,219,864,2814,1677,2023,2599,153,283,284,678,2680,1051,732,1360,2261,1778,245,2174,306,1589,34,822,823,2633,1178,1842,134,1724,824,1180,1532,1362,25,1059,2079,1926,1182,826,176,86,1119,2546,1592,1421,736,385,473,2130,1846,247,1727,1313,144,106,1064,1536,645,308,1851,1371,1124,1934,2742,1318,2088,1542,1544,2848,1793,694,28,509,566,178,1436,1379,2090,1199,139,1941,110,1079,1329,1382,227,1202,701,841,942,66,2417,1866,2000,1698,2648,1083,1950,706,2853,2188,753,1659,2618,955,1502,2916,578,754,1088,212,1505,581,1346,133,353,1348,1818,1029,1460,1218,189,761,714,340,378,141,355,1397,2735,908,80,1400,972,721,277,1761,1672,1575,2208,912,1916,1231,194,2059,2718,1719,61,440 0.09914099907683403,0.9027628846125711,0.24801958368154803,-0.21180894066884262,-0.2519914877556342,0.24801958368154803,1.2776448956782354,0.0612563185418274,0.49884576098804173,0.02309828334687722,0.32091216739564127,1.0307485270519672,-0.5848621144923504,1.1247147016520551,0.3928095936133701,-1.5718746398609995,-0.13234464502495924,-0.4158281796670899,-1.0323962561974658,1.3672844525092513,0.9990456262708737,0.9990456262708737,0.5337207971688037,-1.1742638113510904,0.28459191556669194,0.49884576098804173,0.09914099907683403,-0.6279701240574134,-0.21180894066884262,1.0622595380909912,-0.5420991063561916,0.9671485853633185,-0.05405313922784484,2.871469999732692,0.428393191730484,0.428393191730484,-1.0792715109109947,0.2111917997668451,-0.2519914877556342,1.484439279959394,-0.1719280959561597,0.428393191730484,0.2111917997668451,-0.015336908887356353,0.09914099907683403,3.2128208825072786,0.28459191556669194,-0.4575872142200032,-0.33327939055474815,0.2111917997668451,0.428393191730484,1.2776448956782354,1.8478045517497095,0.24801958368154803,-0.9398534966833773,-0.05405313922784484,0.0612563185418274,0.49884576098804173,0.8375726207273704,0.7382358716884349,-0.4996758503153541,-0.2519914877556342,1.0622595380909912,-0.1719280959561597,0.1367560507410777,1.4261935465788533,1.6832758718136789,0.28459191556669194,-0.015336908887356353,0.5683656165997513,0.9671485853633185,-0.2519914877556342,0.09914099907683403,0.24801958368154803,-0.33327939055474815,-1.3199640839408484,0.1367560507410777,-0.4575872142200032,-0.015336908887356353,-0.015336908887356353,-1.7288348009106087,-0.21180894066884262,0.5337207971688037,3.0663191302423836,0.704699791414857,0.6369761233848037,1.2776448956782354,0.0612563185418274,0.09914099907683403,-0.4575872142200032,0.2111917997668451,1.455398437788666,-0.33327939055474815,1.655335720828877,0.28459191556669194,0.1367560507410777,0.09914099907683403,1.1247147016520551,0.2111917997668451,0.5337207971688037,0.428393191730484,0.35698364577547,2.0592842445697523,-0.759418488288081,-0.2519914877556342,-0.3743938386878874,-0.13234464502495924,-1.0792715109109947,0.28459191556669194,-0.33327939055474815,0.5337207971688037,-1.7288348009106087,-0.5420991063561916,0.49884576098804173,-0.09305436959858496,-1.0323962561974658,0.35698364577547,0.02309828334687722,-2.589360161351481,0.6369761233848037,0.49884576098804173,0.28459191556669194,1.155663166669387,0.02309828334687722,0.6369761233848037,0.1367560507410777,1.5133178288044788,0.9027628846125711,0.1367560507410777,-0.21180894066884262,0.32091216739564127,0.0612563185418274,0.2111917997668451,1.2474172170623723,0.49884576098804173,0.5337207971688037,0.9350551147231273,0.8702695242261951,1.455398437788666,0.9027628846125711,0.09914099907683403,-1.2709592380232988,0.3928095936133701,1.901497527876068,0.09914099907683403,0.35698364577547,0.5337207971688037,1.0307485270519672,-0.1719280959561597,-0.09305436959858496,-0.015336908887356353,-0.5420991063561916,0.3928095936133701,-0.29248013870191797,0.2111917997668451,1.2170123744522818,-0.4158281796670899,-1.222394988641525,-0.13234464502495924,2.1108177774831414,0.8046697182564764 2937 Hedgehog off state 31 49 3.715300035531724 0.0002029627189976 P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P04350,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13885,P17980,Q13200,P20618,Q9Y496,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,502,876,811,549,149,165,539,578,50,840,919,305,686,560,824,834,201,198,326,327,477,105,890,767,747,362,745,735,259,253 149,1106,560,1353,165,919,305,1306,1641,824,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,502,884,50,1251,198,834,1431,1856,477,1374,1127,1259,890,745,1006,747,840,201,578,253,549,1568,1153,811,767,259 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.9671485853633185,0.1367560507410777,-0.09305436959858496,0.428393191730484,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.704699791414857,0.3928095936133701,2.237423692928971,0.17410512476192191,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,-0.015336908887356353,0.24801958368154803,0.463737560425262,0.49884576098804173,1.0622595380909912 2937 Synthesis of dna 50 82 3.692721333901676 0.000221867097667 P33991,P49720,P28066,Q9UJX3,Q9UL46,P27694,Q99460,O00231,P49642,P28340,Q9Y2S7,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,P35251,Q14997,O75832,P35998,P25787,Q9BRT9,O00487,P49643,Q07864,P55036,Q15008,P51665,Q13309,P35244,P49736,P28072,P28074,P30260,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y248,P17980,Q99436,Q16763 Processes and pathways Reactome Pathways msigdb_reactome 246,884,876,810,811,875,549,149,390,643,557,775,778,537,165,290,781,539,578,50,419,840,919,686,926,193,560,928,839,834,201,198,935,450,690,326,327,829,477,826,89,105,890,767,745,735,530,362,253,126 149,1106,560,1353,165,1113,919,1639,1782,362,2439,735,775,826,1183,926,1184,1418,875,876,105,326,327,643,829,246,778,537,450,2131,1534,419,686,1122,2507,2222,1480,539,1595,390,928,884,50,690,781,198,834,89,1431,1856,477,1374,1127,1259,890,839,745,935,1006,290,840,201,126,578,2425,253,549,1215,193,1025,1571,1821,1467,2388,810,1760,1574,811,767,530,557,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,0.35698364577547,-0.09305436959858496,-0.21180894066884262,0.8702695242261951,-0.8039614683338043,0.49884576098804173,0.463737560425262,0.428393191730484,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5683656165997513,0.428393191730484,1.0622595380909912,0.463737560425262,0.6709474376181863,0.7715583169098631,-0.4996758503153541,-0.015336908887356353,0.8046697182564764,0.5337207971688037,0.24801958368154803,-0.8941728675715074,-0.5848621144923504,0.02309828334687722,0.6709474376181863,-0.05405313922784484,0.8375726207273704,0.35698364577547,0.3928095936133701,2.237423692928971,0.5337207971688037,0.463737560425262,1.1864283685836194,0.428393191730484,1.8207460887469624,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.428393191730484,0.49884576098804173,0.35698364577547,0.32091216739564127,0.9990456262708737,0.428393191730484,1.1864283685836194,1.5420358124097335,0.6369761233848037,-0.759418488288081,1.0622595380909912,0.6709474376181863,0.2111917997668451,1.2170123744522818,0.32091216739564127,-0.015336908887356353,-0.21180894066884262,0.0612563185418274,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,0.463737560425262,0.49884576098804173,0.704699791414857,0.6709474376181863,-0.7152427522665485 2937 Hedgehog on state 29 42 3.6727826295244914 0.0002399235612984 P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,P17980,Q13200,P20618,Q9Y496,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,502,876,811,549,149,165,539,578,50,840,919,686,560,834,201,198,326,327,477,832,105,890,767,362,745,735,259,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,832,686,1480,539,502,884,50,198,834,1431,1856,477,1374,1127,890,745,1380,840,201,2326,578,253,549,811,767,259 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.704699791414857,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.09914099907683403,0.428393191730484,1.1864283685836194,-0.6714285051358926,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173,1.0622595380909912 2937 Scf skp2 mediated degradation of p27 p21 28 41 3.650336481042951 0.0002618969961374 P49720,P28066,Q9UL46,O00231,Q99460,P24941,P11802,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,775,158,165,539,578,50,919,686,926,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,158,362,735,775,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1259,890,745,935,1006,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,1.33757659471794,0.8702695242261951,0.49884576098804173,0.463737560425262,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.35698364577547,0.32091216739564127,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Cyclin a cdk2 associated events at s phase entry 29 44 3.645548369790872 0.0002668222200421 P49720,P31751,P28066,Q9UL46,Q99460,O00231,P24941,P11802,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,878,876,811,549,149,775,158,165,539,578,50,919,686,926,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,158,362,735,775,1183,926,1184,1418,876,105,326,327,878,686,1480,539,884,50,1851,198,834,1431,1856,477,1374,1127,1259,890,1602,745,935,1006,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,1.33757659471794,0.8702695242261951,0.49884576098804173,0.463737560425262,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.3928095936133701,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,-0.2519914877556342,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,-0.05405313922784484,0.49884576098804173,0.35698364577547,0.32091216739564127,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Degradation of dvl 26 38 3.633644791454479 0.0002794455116681 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,1380,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.09914099907683403,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Molecular transducer activity 13 28 3.6272839128499226 0.0002864183005242 P04150,P30536,Q15629,Q08722,Q8WTV0,Q14108,O15173,P41214,O15118,O43813,Q99720,O14786,P20645 Functions GO Molecular function msigdb_gomf 221,160,39,424,10,79,231,369,173,112,23,118,25 118,173,231,112,221,2261,1178,25,160,598,369,503,456,1895,424,1003,79,39,1334,943,1271,10,851,23,2009,1963,1099,2057 1.5705949318057502,1.2776448956782354,1.0935808714347506,1.627243250148423,1.1247147016520551,-0.6279701240574134,0.2111917997668451,3.2128208825072786,1.33757659471794,0.6027831121744145,0.8702695242261951,0.704699791414857,0.7715583169098631,-0.29248013870191797,0.8046697182564764,0.32091216739564127,1.901497527876068,2.6457718362497507,0.1367560507410777,0.35698364577547,0.17410512476192191,4.351275402719301,0.428393191730484,3.434730873938129,-0.3743938386878874,-0.33327939055474815,0.28459191556669194,-0.4158281796670899 2937 Cross presentation of soluble exogenous antigens endosomes 26 37 3.626515174477935 0.0002872719449713 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Degradation of axin 26 37 3.626515174477935 0.0002872719449713 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Dna replication 50 87 3.626169694220164 0.0002876563588425 P33991,P49720,P28066,Q9UJX3,Q9UL46,P27694,Q99460,O00231,P49642,P28340,Q9Y2S7,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,P35251,Q14997,O75832,P35998,P25787,Q9BRT9,O00487,P49643,Q07864,P55036,Q15008,P51665,Q13309,P35244,P49736,P28072,P28074,P30260,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y248,P17980,Q99436,Q16763 Processes and pathways Reactome Pathways msigdb_reactome 246,884,876,810,811,875,549,149,390,643,557,775,778,537,165,290,781,539,578,50,419,840,919,686,926,193,560,928,839,834,201,198,935,450,690,326,327,829,477,826,89,105,890,767,745,735,530,362,253,126 149,1106,560,1353,165,1113,1635,919,1639,1782,1888,362,2439,735,775,826,1183,926,1184,1418,875,876,105,326,327,643,829,246,778,537,450,2131,1534,419,686,1122,2507,2222,1480,539,1595,390,928,884,50,690,781,198,2031,834,89,1431,1856,477,1374,1127,1690,1259,890,839,745,935,1006,290,1693,840,201,126,578,2425,253,549,1215,193,1025,1571,1821,1467,2388,810,1760,1574,811,767,530,557,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,-0.09305436959858496,0.35698364577547,-0.09305436959858496,-0.21180894066884262,-0.29248013870191797,0.8702695242261951,-0.8039614683338043,0.49884576098804173,0.463737560425262,0.428393191730484,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5683656165997513,0.428393191730484,1.0622595380909912,0.463737560425262,0.6709474376181863,0.7715583169098631,-0.4996758503153541,-0.015336908887356353,0.8046697182564764,0.5337207971688037,0.24801958368154803,-0.8941728675715074,-0.5848621144923504,0.02309828334687722,0.6709474376181863,-0.05405313922784484,0.8375726207273704,0.35698364577547,0.3928095936133701,2.237423692928971,0.5337207971688037,0.463737560425262,1.1864283685836194,-0.4158281796670899,0.428393191730484,1.8207460887469624,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,-0.13234464502495924,0.17410512476192191,0.3928095936133701,0.428393191730484,0.49884576098804173,0.35698364577547,0.32091216739564127,0.9990456262708737,-0.13234464502495924,0.428393191730484,1.1864283685836194,1.5420358124097335,0.6369761233848037,-0.759418488288081,1.0622595380909912,0.6709474376181863,0.2111917997668451,1.2170123744522818,0.32091216739564127,-0.015336908887356353,-0.21180894066884262,0.0612563185418274,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,0.463737560425262,0.49884576098804173,0.704699791414857,0.6709474376181863,-0.7152427522665485 2937 Degradation of gli1 by the proteasome 27 40 3.603928170834662 0.0003134437133416 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,824,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,824,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1259,890,745,1006,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.428393191730484,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Proteasome complex 29 45 3.6012835641469323 0.000316649973675 P49720,Q5VYK3,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P54727,P28070,Q16186,Q9UNM6,Q06323,Q13200,P20618,P17980,Q99436 Localization GO Cellular component msigdb_gocc 884,270,876,811,549,149,165,539,578,50,840,919,686,560,834,201,198,326,327,477,224,105,515,767,890,745,735,362,253 149,1106,560,1353,165,1043,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,998,224,834,1934,1431,1856,477,1374,1127,890,745,840,201,1441,515,270,578,253,549,811,767,1233 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.28459191556669194,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.32091216739564127,1.1247147016520551,0.428393191730484,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.0612563185418274,0.704699791414857,1.0307485270519672,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173,0.2111917997668451 2937 Metabolism of polyamines 27 39 3.600942148645061 0.0003170661284717 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,P52788 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253,741 149,1106,560,1353,165,919,362,1979,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,741,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,-0.3743938386878874,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.49884576098804173,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Orc1 removal from chromatin 34 51 3.5963731037796047 0.0003226848836896 P33991,P49720,P28066,Q9UL46,Q99460,O00231,P24941,P33992,P33993,Q14566,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P49736,P28072,P28074,P62191,P25205,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 246,884,876,811,549,149,775,778,537,290,165,539,578,50,840,919,686,926,560,834,201,198,690,326,327,477,826,105,890,767,745,735,362,253 149,1106,560,1353,165,1113,919,362,735,775,826,1183,926,1184,1418,876,105,326,327,246,778,537,686,1480,539,884,50,690,198,834,1431,1856,477,1374,1127,1259,890,745,935,1006,290,840,201,578,253,549,1215,1467,811,767,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,0.35698364577547,0.8702695242261951,0.49884576098804173,0.463737560425262,0.428393191730484,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,1.0622595380909912,0.463737560425262,0.6709474376181863,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,0.5337207971688037,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.35698364577547,0.32091216739564127,0.9990456262708737,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.2111917997668451,0.0612563185418274,0.463737560425262,0.49884576098804173,-0.7152427522665485 2937 Transcriptional regulation by runx2 34 53 3.5924172046225578 0.0003276247652661 P14635,P49720,P31751,P28066,Q9UL46,P06493,Q99460,O00231,P11802,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,Q9UBN7,P27361,P28072,P28074,P62191,P04150,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 873,884,878,876,811,263,549,149,158,165,539,578,50,840,919,686,926,560,834,201,198,80,828,326,327,477,221,105,890,767,745,735,362,253 149,1106,560,1353,165,919,221,263,158,873,362,735,1183,926,1184,1418,828,876,105,326,327,1247,878,686,1727,1480,539,884,50,1251,198,834,1431,1856,477,1374,1127,1259,890,745,935,2318,1006,840,201,578,1750,253,549,80,811,1102,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,1.1247147016520551,1.0307485270519672,1.33757659471794,0.3928095936133701,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.428393191730484,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.17410512476192191,0.3928095936133701,0.5337207971688037,-0.1719280959561597,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,0.17410512476192191,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.35698364577547,-0.6714285051358926,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,-0.1719280959561597,1.0622595380909912,0.6709474376181863,1.901497527876068,0.463737560425262,0.28459191556669194,0.49884576098804173 2937 Signaling by notch4 29 43 3.591232842190067 0.0003291174341586 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q99436,Q13200,P20618,Q9Y6A5,P17980,Q06330,P63104 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,919,686,926,560,834,201,198,326,327,477,105,890,767,253,745,735,1037,362,125,507 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,507,1259,1895,890,125,745,1006,201,578,1612,253,549,811,767,1037 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.704699791414857,0.17410512476192191,-0.29248013870191797,0.3928095936133701,1.5420358124097335,0.49884576098804173,0.32091216739564127,1.1864283685836194,0.6369761233848037,-0.05405313922784484,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173,0.32091216739564127 2937 The role of gtse1 in g2 m progression after g2 checkpoint 33 50 3.5853043178610866 0.0003366853745121 P07900,P14635,P49720,P28066,Q9UL46,P06493,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P08238,P04350,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13885,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 245,873,884,876,811,263,549,149,165,539,578,50,840,919,306,305,686,926,560,834,201,198,326,327,477,105,890,767,747,745,735,362,253 149,1106,560,1353,165,919,1679,305,2025,263,245,306,873,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,1484,834,1431,1856,477,1374,1127,890,745,747,840,201,1010,578,253,549,1568,1153,2387,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.13234464502495924,0.9671485853633185,-0.4158281796670899,1.0307485270519672,1.0622595380909912,0.9671485853633185,0.3928095936133701,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.02309828334687722,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.49884576098804173,0.428393191730484,1.1864283685836194,0.32091216739564127,0.6369761233848037,1.0622595380909912,0.6709474376181863,-0.015336908887356353,0.24801958368154803,-0.7152427522665485,0.463737560425262,0.49884576098804173 2937 Proteasome 24 36 3.577243889477604 0.0003472361624223 P49720,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways KEGG Pathways msigdb_kegg 884,811,149,549,165,539,578,50,840,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Regulation of runx3 expression and activity 25 36 3.575256087909006 0.0003498852444232 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Negative regulation of notch4 signaling 28 40 3.551585320793309 0.0003829178221537 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y6A5,P17980,Q99436,P63104 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,919,686,926,560,834,201,198,326,327,477,105,890,767,745,735,1037,362,253,507 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,507,1259,890,745,1006,201,578,253,549,811,767,1037 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.704699791414857,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.32091216739564127,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173,0.32091216739564127 2937 Abc transporter disorders 27 41 3.5392650670751498 0.0004012427397088 P49720,P28066,Q9UL46,O95342,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,22,549,149,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,2068,22,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1934,1431,1856,477,1374,1127,890,745,840,201,578,253,549,2009,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.4575872142200032,3.513047173839545,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,-0.3743938386878874,0.463737560425262,0.49884576098804173 2937 G1 s dna damage checkpoints 27 40 3.5374625938876925 0.0004039914062563 P49720,P28066,Q9UL46,O00231,Q99460,P24941,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,775,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,1053,2025,362,735,775,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.28459191556669194,-0.4158281796670899,0.8702695242261951,0.49884576098804173,0.463737560425262,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Runx1 regulates transcription of genes involved in differentiation of hscs 26 40 3.5266578789696905 0.0004208401751801 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,1888,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,1851,198,834,1431,1856,477,1374,1127,1690,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.29248013870191797,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,-0.2519914877556342,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,-0.13234464502495924,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Regulation of runx2 expression and activity 28 44 3.517938276778208 0.000434913509216 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P04150,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,926,560,834,201,198,326,327,477,221,105,890,767,745,735,362,253 149,1106,560,1353,165,919,221,362,735,1183,926,1184,1418,876,105,326,327,686,1727,1480,539,884,50,1251,198,834,1431,1856,477,1374,1127,1259,890,745,935,1006,840,201,578,253,549,811,1102,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,1.1247147016520551,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,-0.1719280959561597,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,0.17410512476192191,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.35698364577547,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.28459191556669194,0.49884576098804173 2937 transporter 22 57 3.4866475595719275 0.0004891154713368 Q567V2,O43772,Q9HAV4,Q9HD45,O60830,P37198,Q9NR77,Q9UIA9,Q99595,P53985,Q6N075,Q92973,P48739,P55060,Q96P70,Q9H2D1,Q00169,O15397,Q92544,Q8N1F7,O14617,O95373 Functions Panther Protein class panther_protein_class 3,4,405,274,9,386,13,554,27,161,30,432,540,288,580,188,455,195,91,350,469,244 814,1766,1168,469,2015,859,195,1112,2019,4,1635,9,2462,244,1422,386,540,1788,996,2031,2407,2509,161,2227,288,2228,1988,1730,455,2666,1693,896,3,30,2097,350,2670,1611,623,91,432,2376,580,1752,27,1024,1564,1753,188,405,274,13,1288,554,909,2391,2392 0.428393191730484,-0.21180894066884262,0.2111917997668451,0.7382358716884349,-0.4158281796670899,0.3928095936133701,1.1864283685836194,0.24801958368154803,-0.4158281796670899,4.835200926172848,-0.09305436959858496,4.351275402719301,-0.8488775839823314,1.0622595380909912,0.0612563185418274,0.8375726207273704,0.6709474376181863,-0.21180894066884262,0.32091216739564127,-0.4158281796670899,-0.759418488288081,-0.8941728675715074,1.33757659471794,-0.5848621144923504,0.9990456262708737,-0.5848621144923504,-0.3743938386878874,-0.1719280959561597,0.7715583169098631,-1.1265583700744997,-0.13234464502495924,0.3928095936133701,4.952686465214834,3.0450375649426276,-0.4575872142200032,0.9027628846125711,-1.1265583700744997,-0.05405313922784484,0.6027831121744145,1.8207460887469624,0.8046697182564764,-0.7152427522665485,0.6369761233848037,-0.1719280959561597,3.1296290705170495,0.32091216739564127,-0.015336908887356353,-0.1719280959561597,1.2474172170623723,0.8375726207273704,1.0307485270519672,4.2518449635579465,0.17410512476192191,0.6709474376181863,0.3928095936133701,-0.7152427522665485,-0.7152427522665485 2937 Tnfr2 non canonical nf kb pathway 28 41 3.478106660218569 0.0005049689490614 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,Q8TBC4,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,926,560,834,201,198,326,327,1017,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1935,1856,477,1374,1127,1259,890,745,1006,840,201,1017,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.33327939055474815,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.32091216739564127,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Stabilization of p53 26 39 3.474924519830683 0.000510997112106 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,1053,2025,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.28459191556669194,-0.4158281796670899,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Regulation of actin filament based process 29 81 3.471624330822506 0.0005173197156231 O15144,P46940,P15311,Q13177,Q14019,P42345,P16949,Q9UQB8,P59998,Q9Y5K6,Q13576,Q13813,Q08722,P35611,P53367,Q86VI3,Q01082,P35579,P35241,Q07157,Q13045,O75122,P62993,P52565,P35080,O14786,Q9UJU6,Q9NUQ9,Q68EM7 Processes and pathways GO Biological process msigdb_gobp 487,131,134,139,140,265,143,18,266,440,545,426,424,287,51,313,310,63,76,479,226,471,236,371,366,118,120,128,251 118,487,860,2395,1972,471,2599,1114,1680,983,2604,2075,134,1179,1243,143,2026,1845,366,76,63,287,265,131,2226,1787,371,1196,51,1318,266,2759,1254,1319,601,931,236,2511,1733,1937,310,1895,479,424,1379,2090,226,139,2318,1736,545,426,140,570,786,2093,2447,2040,251,1698,313,958,755,1505,1957,1751,853,1348,667,1757,128,1963,1100,1399,120,18,1470,2347,440,1105,1577 1.5705949318057502,0.704699791414857,0.3928095936133701,-0.759418488288081,-0.3743938386878874,0.7382358716884349,-1.0323962561974658,0.24801958368154803,-0.13234464502495924,0.32091216739564127,-1.0323962561974658,-0.4575872142200032,1.484439279959394,0.2111917997668451,0.17410512476192191,1.4261935465788533,-0.4158281796670899,-0.2519914877556342,0.8702695242261951,1.9281348523770536,2.085115891068643,0.9990456262708737,1.0307485270519672,1.5133178288044788,-0.5848621144923504,-0.21180894066884262,0.8702695242261951,0.2111917997668451,2.237423692928971,0.1367560507410777,1.0307485270519672,-1.3694172456596465,0.17410512476192191,0.1367560507410777,0.6027831121744145,0.35698364577547,1.0935808714347506,-0.8941728675715074,-0.1719280959561597,-0.33327939055474815,0.9671485853633185,-0.29248013870191797,0.7382358716884349,0.8046697182564764,0.09914099907683403,-0.4575872142200032,1.1247147016520551,1.455398437788666,-0.6714285051358926,-0.1719280959561597,0.6709474376181863,0.8046697182564764,1.455398437788666,0.6369761233848037,0.463737560425262,-0.4575872142200032,-0.8039614683338043,-0.4158281796670899,1.0622595380909912,-0.13234464502495924,0.9671485853633185,0.35698364577547,0.49884576098804173,0.02309828334687722,-0.33327939055474815,-0.1719280959561597,0.428393191730484,0.1367560507410777,0.5683656165997513,-0.1719280959561597,1.5420358124097335,-0.33327939055474815,0.28459191556669194,0.09914099907683403,1.5705949318057502,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.8046697182564764,0.28459191556669194,-0.015336908887356353 2937 Proteasome degradation 25 41 3.469395702014417 0.0005216305558659 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,P49721,O75832,P22314,P35998,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P04439,P17980,Q99436 Processes and pathways WikiPathways msigdb_wp 884,876,811,149,549,165,539,50,919,924,686,834,201,198,326,327,477,105,890,767,745,735,232,362,253 149,1106,1353,165,919,1054,232,1238,1304,1415,1888,362,735,924,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,201,253,549,811,767 1.3968228224013606,0.24801958368154803,0.09914099907683403,1.3076973767692464,0.35698364577547,0.28459191556669194,1.0935808714347506,0.17410512476192191,0.1367560507410777,0.0612563185418274,-0.29248013870191797,0.8702695242261951,0.49884576098804173,0.35698364577547,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,1.1864283685836194,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Developmental biology 92 250 3.4664974253981797 0.0005272867847281 O15144,Q9NR77,P60866,P62081,P62280,Q99460,Q16850,P09496,P61353,P48556,Q92530,P49721,Q96P70,Q15370,Q14126,P35579,P05387,O00487,P35241,P39019,P62899,P42766,P61927,P62829,P28070,P35580,P62495,O14786,Q7Z406,P40763,P46782,Q06330,Q8N8S7,P15311,P61254,Q13177,O00231,P46783,P62917,P62277,P11802,O43242,Q04637,P26038,Q9Y490,P35998,P08865,Q9UQ16,P18077,Q15008,P51665,P62861,Q9UNM6,Q9Y3U8,Q13885,Q13200,P20618,P62993,P19174,Q9BZI7,P46779,Q99436,P62241,P07900,O60271,P59998,Q15418,P83881,Q01082,P50570,P08238,P04350,P26373,P28072,P28074,Q9HAU5,P62847,Q9Y2W1,P35268,P35080,P17980,P23396,P39023,P46776,Q13617,Q13813,P62750,Q00169,P62701,P62191,O75122,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 487,13,504,505,506,549,31,535,542,539,578,50,580,572,570,63,562,560,76,82,83,95,604,607,105,113,606,118,119,598,599,125,660,134,136,139,149,155,650,649,158,165,171,176,723,686,680,194,682,201,198,225,767,243,747,745,735,236,234,255,738,253,743,245,261,266,292,289,310,308,306,305,325,326,327,355,372,379,367,366,362,384,387,389,425,426,423,455,454,477,471,508 149,1106,560,2302,118,1353,487,860,1832,165,2395,2842,261,471,2823,1774,2571,919,2788,1114,1526,1678,1302,1411,1412,2502,305,982,2603,562,1638,2261,1474,983,245,306,1414,680,535,1837,823,158,770,1641,2075,1978,134,1530,1179,1888,824,362,682,874,1477,234,1642,1361,1478,735,384,1364,1785,775,1245,1183,926,1184,1418,176,325,828,1419,876,105,326,327,1247,2355,1644,1929,878,1931,366,1121,2130,76,367,63,113,2308,686,1846,1311,1786,82,387,1645,598,95,1480,389,1189,737,738,1482,599,155,1593,1314,539,927,884,50,1251,308,1933,1539,198,1855,1599,834,266,2229,504,1431,1254,2360,1067,1197,136,1856,1650,542,1432,931,604,2664,505,477,1374,743,1489,1857,1936,1433,887,1689,649,506,1127,1128,2361,606,454,423,1544,1690,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,236,1546,2761,2548,1731,1600,289,1651,455,1937,508,310,932,1691,1071,1549,2444,171,2579,890,125,1131,1602,2708,2365,139,745,2318,425,426,747,570,938,1553,840,201,2643,2273,2092,572,292,2323,2512,2093,1011,1898,31,1558,119,1142,660,2916,578,1612,1954,958,2485,1748,2152,580,1344,253,549,1457,1568,1153,255,355,13,2245,1963,811,2346,767,194,379,2495,243,723,2166 1.3968228224013606,0.24801958368154803,0.6369761233848037,-0.6714285051358926,1.5705949318057502,0.09914099907683403,0.704699791414857,0.3928095936133701,-0.2519914877556342,1.3076973767692464,-0.759418488288081,-1.7288348009106087,1.0307485270519672,0.7382358716884349,-1.623692476299974,-0.21180894066884262,-0.9859257988083908,0.35698364577547,-1.469700408349865,0.24801958368154803,-0.015336908887356353,-0.13234464502495924,0.1367560507410777,0.0612563185418274,0.0612563185418274,-0.8941728675715074,0.9671485853633185,0.32091216739564127,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,-0.6279701240574134,0.02309828334687722,0.32091216739564127,1.0622595380909912,0.9671485853633185,0.0612563185418274,0.5337207971688037,0.6709474376181863,-0.2519914877556342,0.428393191730484,1.33757659471794,0.463737560425262,-0.09305436959858496,-0.4575872142200032,-0.3743938386878874,1.484439279959394,-0.015336908887356353,0.2111917997668451,-0.29248013870191797,0.428393191730484,0.8702695242261951,0.5337207971688037,0.3928095936133701,0.02309828334687722,1.0935808714347506,-0.09305436959858496,0.09914099907683403,0.02309828334687722,0.49884576098804173,0.8375726207273704,0.09914099907683403,-0.21180894066884262,0.463737560425262,0.17410512476192191,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,1.2776448956782354,0.9350551147231273,0.428393191730484,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.17410512476192191,-0.7152427522665485,-0.09305436959858496,-0.33327939055474815,0.3928095936133701,-0.33327939055474815,0.8702695242261951,0.24801958368154803,-0.4996758503153541,1.9281348523770536,0.8702695242261951,2.085115891068643,1.627243250148423,-0.6714285051358926,0.5337207971688037,-0.2519914877556342,0.1367560507410777,-0.21180894066884262,1.8747212260962505,0.8375726207273704,-0.09305436959858496,0.6027831121744145,1.7387054861501252,0.02309828334687722,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,-0.05405313922784484,0.1367560507410777,0.6709474376181863,0.35698364577547,0.3928095936133701,2.237423692928971,0.17410512476192191,0.9671485853633185,-0.33327939055474815,-0.015336908887356353,1.1864283685836194,-0.2519914877556342,-0.05405313922784484,0.428393191730484,1.0307485270519672,-0.5848621144923504,0.704699791414857,0.0612563185418274,0.17410512476192191,-0.7152427522665485,0.28459191556669194,0.2111917997668451,1.484439279959394,-0.2519914877556342,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.35698364577547,0.6027831121744145,-1.1265583700744997,0.704699791414857,0.7382358716884349,0.09914099907683403,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.24801958368154803,-0.7152427522665485,0.6027831121744145,0.7715583169098631,0.8046697182564764,-0.015336908887356353,-0.13234464502495924,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,1.0935808714347506,-0.015336908887356353,-1.3694172456596465,-0.9398534966833773,-0.1719280959561597,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,0.7715583169098631,-0.33327939055474815,0.704699791414857,0.9671485853633185,0.35698364577547,-0.13234464502495924,0.28459191556669194,-0.015336908887356353,-0.8039614683338043,1.3076973767692464,-0.9859257988083908,0.3928095936133701,1.5420358124097335,0.24801958368154803,-0.05405313922784484,-1.222394988641525,-0.7152427522665485,1.455398437788666,0.49884576098804173,-0.6714285051358926,0.8046697182564764,0.8046697182564764,0.49884576098804173,0.6369761233848037,0.35698364577547,-0.015336908887356353,0.428393191730484,1.1864283685836194,-1.0792715109109947,-0.6279701240574134,-0.4575872142200032,0.6369761233848037,0.9990456262708737,-0.6714285051358926,-0.8941728675715074,-0.4575872142200032,0.32091216739564127,-0.29248013870191797,3.0236656669194946,-0.015336908887356353,1.5705949318057502,0.24801958368154803,0.5683656165997513,-2.589360161351481,0.6369761233848037,-0.05405313922784484,-0.33327939055474815,0.35698364577547,-0.8488775839823314,-0.1719280959561597,-0.4996758503153541,0.6369761233848037,0.1367560507410777,1.0622595380909912,0.6709474376181863,0.0612563185418274,-0.015336908887356353,0.24801958368154803,1.0622595380909912,0.9027628846125711,4.2518449635579465,-0.5848621144923504,-0.33327939055474815,0.463737560425262,-0.6714285051358926,0.49884576098804173,1.2170123744522818,0.8702695242261951,-0.8488775839823314,1.0935808714347506,0.5337207971688037,-0.4996758503153541 2937 Switching of origins to a post replicative state 37 59 3.428310887773775 0.0006073495144955 P33991,P49720,P28066,Q9UJX3,Q9UL46,Q99460,O00231,P24941,P33992,P33993,Q14566,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P49736,P28072,P28074,P30260,P62191,P25205,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q16763 Processes and pathways Reactome Pathways msigdb_reactome 246,884,876,810,811,549,149,775,778,537,290,165,539,578,50,840,919,686,926,560,834,201,198,690,326,327,829,477,826,105,890,767,745,735,362,253,126 149,1106,560,1353,165,1113,919,362,735,775,826,1183,926,1184,1418,876,105,326,327,829,246,778,537,686,1480,539,884,50,690,198,834,1431,1856,477,1374,1127,1259,890,745,935,1006,290,840,201,126,578,2425,253,549,1215,1571,1467,2388,810,1760,1574,811,767,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,0.35698364577547,0.8702695242261951,0.49884576098804173,0.463737560425262,0.428393191730484,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,1.0622595380909912,0.463737560425262,0.6709474376181863,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,0.5337207971688037,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.35698364577547,0.32091216739564127,0.9990456262708737,0.428393191730484,1.1864283685836194,1.5420358124097335,0.6369761233848037,-0.759418488288081,1.0622595380909912,0.6709474376181863,0.2111917997668451,-0.015336908887356353,0.0612563185418274,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,0.463737560425262,0.49884576098804173,-0.7152427522665485 2937 Alpha/Beta hydrolase fold [IPR029058] 7 22 3.4238092372541677 0.0006174995106715 P07099,Q4J6C6,P42785,Q8NCC3,Q9H3G5,P50897,Q9H6V9 Sequence InterPro Superfamily interpro_homologous_superfamily 32,33,6,12,17,49,19 2255,32,2073,1839,208,2930,6,1594,503,49,33,1557,2275,2003,12,1149,17,19,55,1162,2159,1628 -0.6279701240574134,2.980647915116571,-0.4575872142200032,-0.2519914877556342,1.155663166669387,-4.749744545709802,4.496753993926139,-0.05405313922784484,0.704699791414857,2.3364949483641926,2.959000560087587,-0.015336908887356353,-0.6279701240574134,-0.3743938386878874,4.268556610395897,0.24801958368154803,3.7962488360202657,3.6848923107300693,2.1871572148884817,0.24801958368154803,-0.4996758503153541,-0.05405313922784484 2937 Protein polymerization 30 68 3.421962675161631 0.0006217084761845 O15144,O60610,P07900,Q9BSJ2,Q14019,P42345,P16949,Q9UQB8,P23396,P59998,Q9BTW9,Q13813,P35611,Q96P70,Q01082,P04350,P35241,P61086,Q14203,P45880,Q13045,O75122,O00429,Q96CW5,P62993,P35080,Q02790,Q9UJU6,Q9NUQ9,Q16763 Processes and pathways GO Biological process msigdb_gobp 487,488,245,403,140,265,143,18,384,266,163,426,287,580,310,305,76,452,211,329,226,471,345,376,236,366,509,120,128,126 345,487,860,2395,863,488,471,1114,1680,305,983,245,822,143,384,366,76,287,1310,2682,265,329,645,2226,1787,1852,1196,2086,1318,266,452,931,236,310,509,2412,1379,226,568,426,697,140,211,786,1863,1010,2093,2447,126,1698,958,376,1505,580,1344,853,403,163,1623,128,1963,1100,120,2887,18,1232,2347,1105 0.9027628846125711,0.704699791414857,0.3928095936133701,-0.759418488288081,0.3928095936133701,0.704699791414857,0.7382358716884349,0.24801958368154803,-0.13234464502495924,0.9671485853633185,0.32091216739564127,1.0622595380909912,0.428393191730484,1.4261935465788533,0.8375726207273704,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.1367560507410777,-1.1742638113510904,1.0307485270519672,0.9350551147231273,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,-0.2519914877556342,0.2111917997668451,-0.4575872142200032,0.1367560507410777,1.0307485270519672,0.7715583169098631,0.35698364577547,1.0935808714347506,0.9671485853633185,0.704699791414857,-0.759418488288081,0.09914099907683403,1.1247147016520551,0.6369761233848037,0.8046697182564764,0.5337207971688037,1.455398437788666,1.155663166669387,0.463737560425262,-0.2519914877556342,0.32091216739564127,-0.4575872142200032,-0.8039614683338043,1.5420358124097335,-0.13234464502495924,0.35698364577547,0.8702695242261951,0.02309828334687722,0.6369761233848037,0.1367560507410777,0.428393191730484,0.8375726207273704,1.33757659471794,-0.05405313922784484,1.5420358124097335,-0.33327939055474815,0.28459191556669194,1.5705949318057502,-2.0009314909515403,3.7962488360202657,0.2111917997668451,-0.6714285051358926,0.28459191556669194 2937 Tcr signaling 30 46 3.405656348157795 0.0006600520696713 P49720,Q13177,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P19174,P41240,P17980,Q99436,Q8N8S7 Processes and pathways Reactome Pathways msigdb_reactome 884,139,876,811,549,149,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,234,370,362,253,660 149,1106,560,1353,1919,165,919,362,234,735,1183,926,1184,1418,876,105,326,327,686,370,1480,539,884,50,198,834,1431,1856,477,1374,1127,1259,2444,890,139,745,1006,840,201,2093,660,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,0.8702695242261951,1.0935808714347506,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.8702695242261951,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,-0.8039614683338043,0.3928095936133701,1.455398437788666,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,-0.4575872142200032,0.5683656165997513,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Regulation of protein containing complex assembly 29 93 3.390964339907774 0.0006964716258748 O15144,P07900,Q14019,P42345,P16949,Q9UQB8,P23396,P59998,Q86VP6,Q9BTW9,Q13813,Q04637,P35611,P09429,P26038,Q96QK1,Q01082,P04350,Q969V3,P35241,Q9UBN7,Q14203,P45880,Q13045,P62993,P35080,Q02790,Q9UJU6,Q9NUQ9 Processes and pathways GO Biological process msigdb_gobp 487,245,140,265,143,18,384,266,296,163,426,171,287,415,176,581,310,305,337,76,80,211,329,226,236,366,509,120,128 1721,487,860,2395,1114,1526,1680,732,981,305,2025,983,245,415,922,822,823,143,1532,1683,384,176,366,76,287,1310,2682,1645,265,329,645,2226,1787,1251,1852,1853,1196,1486,1934,1318,266,1254,931,1127,236,1793,310,509,171,2579,1379,226,1991,426,697,140,211,786,1863,2184,1010,2093,2447,2040,1558,1698,296,958,337,755,1505,581,1346,853,163,2055,2339,582,128,2204,1963,1825,80,1100,120,1102,912,18,1232,2347,722,1105,1038 -0.1719280959561597,0.704699791414857,0.3928095936133701,-0.759418488288081,0.24801958368154803,-0.015336908887356353,-0.13234464502495924,0.49884576098804173,0.32091216739564127,0.9671485853633185,-0.4158281796670899,0.32091216739564127,1.0622595380909912,0.8046697182564764,0.35698364577547,0.428393191730484,0.428393191730484,1.4261935465788533,-0.015336908887356353,-0.13234464502495924,0.8375726207273704,1.2776448956782354,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.1367560507410777,-1.1742638113510904,-0.09305436959858496,1.0307485270519672,0.9350551147231273,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,0.17410512476192191,-0.2519914877556342,-0.2519914877556342,0.2111917997668451,0.02309828334687722,-0.33327939055474815,0.1367560507410777,1.0307485270519672,0.17410512476192191,0.35698364577547,0.24801958368154803,1.0935808714347506,-0.21180894066884262,0.9671485853633185,0.704699791414857,1.3076973767692464,-0.9859257988083908,0.09914099907683403,1.1247147016520551,-0.3743938386878874,0.8046697182564764,0.5337207971688037,1.455398437788666,1.155663166669387,0.463737560425262,-0.2519914877556342,-0.5420991063561916,0.32091216739564127,-0.4575872142200032,-0.8039614683338043,-0.4158281796670899,-0.015336908887356353,-0.13234464502495924,0.9990456262708737,0.35698364577547,0.9350551147231273,0.49884576098804173,0.02309828334687722,0.6369761233848037,0.1367560507410777,0.428393191730484,1.33757659471794,-0.4158281796670899,-0.6714285051358926,0.6369761233848037,1.5420358124097335,-0.5420991063561916,-0.33327939055474815,-0.21180894066884262,1.901497527876068,0.28459191556669194,1.5705949318057502,0.28459191556669194,0.3928095936133701,3.7962488360202657,0.2111917997668451,-0.6714285051358926,0.5337207971688037,0.28459191556669194,0.32091216739564127 2937 Cdt1 association with the cdc6 orc origin complex 26 41 3.3876145087143854 0.0007050328003295 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,1113,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,840,201,578,253,549,1215,1467,811,767,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.2111917997668451,0.0612563185418274,0.463737560425262,0.49884576098804173,-0.7152427522665485 2937 Regulation of pten stability and activity 27 42 3.3655820660076023 0.0007638234211089 P49720,P31751,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,878,876,811,549,149,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,2604,362,1478,735,1183,926,1184,1418,876,105,326,327,878,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1731,890,745,840,201,578,253,549,811,1102,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-1.0323962561974658,0.8702695242261951,0.02309828334687722,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.3928095936133701,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,-0.1719280959561597,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.28459191556669194,0.49884576098804173 2937 Defective cftr causes cystic fibrosis 26 40 3.365574724491537 0.0007638437481145 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,2068,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1934,1431,1856,477,1374,1127,890,745,840,201,578,253,549,2009,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.4575872142200032,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,-0.3743938386878874,0.463737560425262,0.49884576098804173 2937 Transcriptional regulation by runx3 27 41 3.3592968431404184 0.0007814108195631 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P25440,P48556,Q92530,P49721,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q06330,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,416,539,578,50,919,686,560,834,201,198,326,327,477,105,890,767,125,745,735,362,253 149,1106,560,1353,165,919,2025,362,735,416,1183,926,1184,1418,876,105,326,327,2130,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,125,745,2318,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.4158281796670899,0.8702695242261951,0.49884576098804173,0.8046697182564764,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,-0.4996758503153541,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,1.5420358124097335,0.49884576098804173,-0.6714285051358926,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Antigen processing ubiquitination proteasome degradation 50 85 3.354378748665634 0.0007954340522882 P49720,Q9UIQ6,P55786,Q14139,P28066,Q9UJX3,Q9UL46,Q99460,O00231,Q13867,O43242,Q13617,P48556,O94822,Q92530,Q9Y3I1,P49721,Q14997,Q9UII4,Q5T4S7,Q15370,O75832,Q93034,P35998,P22314,P25787,O00487,Q92990,P55036,Q15819,Q15008,P51665,O95714,Q13309,P61086,P28072,P28074,P30260,P62191,Q7Z6Z7,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9ULT8,O95376,P17980,Q99436,Q16763 Processes and pathways Reactome Pathways msigdb_reactome 884,277,135,655,876,810,811,549,149,427,165,425,539,413,578,975,50,840,721,944,572,919,851,686,924,926,560,335,834,611,201,198,820,935,452,326,327,829,477,752,105,890,767,745,735,910,731,362,253,126 1764,149,1106,560,1353,165,919,413,1586,1359,731,820,362,735,924,1183,926,1184,1418,876,105,326,327,2028,829,686,1480,539,884,50,198,1986,834,135,1431,1935,452,1856,477,1374,1127,1259,1068,890,1199,745,935,1006,425,1380,427,655,2140,840,201,2689,572,1441,611,126,2884,2417,944,1949,752,1017,578,335,851,253,549,1713,1571,721,277,2388,810,1760,1574,811,910,1102,767,975,1293 -0.21180894066884262,1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8046697182564764,-0.05405313922784484,0.09914099907683403,0.49884576098804173,0.428393191730484,0.8702695242261951,0.49884576098804173,0.35698364577547,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,-0.4158281796670899,0.428393191730484,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,-0.3743938386878874,0.428393191730484,1.484439279959394,0.0612563185418274,-0.33327939055474815,0.7715583169098631,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.28459191556669194,0.3928095936133701,0.2111917997668451,0.49884576098804173,0.35698364577547,0.32091216739564127,0.8046697182564764,0.09914099907683403,0.8046697182564764,0.5683656165997513,-0.4996758503153541,0.428393191730484,1.1864283685836194,-1.1742638113510904,0.6369761233848037,0.0612563185418274,0.6027831121744145,1.5420358124097335,-2.0009314909515403,-0.759418488288081,0.35698364577547,-0.33327939055474815,0.49884576098804173,0.32091216739564127,0.6369761233848037,0.9350551147231273,0.428393191730484,1.0622595380909912,0.6709474376181863,-0.13234464502495924,-0.015336908887356353,0.5337207971688037,1.0307485270519672,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,0.463737560425262,0.3928095936133701,0.28459191556669194,0.49884576098804173,0.35698364577547,0.17410512476192191 2937 Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 30 49 3.3467720177442675 0.0008175842048647 P49720,P28066,Q9UJX3,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P30260,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q16763 Processes and pathways Reactome Pathways msigdb_reactome 884,876,810,811,549,149,165,539,578,50,840,919,686,926,560,834,201,198,326,327,829,477,105,890,767,745,735,362,253,126 149,1106,560,1353,1767,165,919,362,735,1183,926,1184,1418,876,105,326,327,829,686,1480,539,884,50,198,1484,834,1431,1856,477,1374,1127,890,1199,745,935,840,201,126,578,2425,253,549,1571,2388,810,1760,1574,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.21180894066884262,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.02309828334687722,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.2111917997668451,0.49884576098804173,0.35698364577547,0.428393191730484,1.1864283685836194,1.5420358124097335,0.6369761233848037,-0.759418488288081,1.0622595380909912,0.6709474376181863,-0.015336908887356353,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,0.463737560425262,0.49884576098804173 2937 Negative regulation of protein containing complex assembly 14 33 3.343431848169069 0.0008274901665759 P45880,Q13813,P35241,P35611,Q9UBN7,P16949,P09429,P35080,Q02790,Q01082,Q9NUQ9,P04350,Q13045,Q9BTW9 Processes and pathways GO Biological process msigdb_gobp 329,426,76,287,80,143,415,366,509,310,128,305,226,163 1721,1114,981,305,983,415,143,366,76,287,1645,329,2226,1787,1251,1196,1318,1254,310,509,1379,226,426,2184,1010,581,1346,853,163,128,1825,80,1100 -0.1719280959561597,0.24801958368154803,0.32091216739564127,0.9671485853633185,0.32091216739564127,0.8046697182564764,1.4261935465788533,0.8702695242261951,1.9281348523770536,0.9990456262708737,-0.09305436959858496,0.9350551147231273,-0.5848621144923504,-0.21180894066884262,0.17410512476192191,0.2111917997668451,0.1367560507410777,0.17410512476192191,0.9671485853633185,0.704699791414857,0.09914099907683403,1.1247147016520551,0.8046697182564764,-0.5420991063561916,0.32091216739564127,0.6369761233848037,0.1367560507410777,0.428393191730484,1.33757659471794,1.5420358124097335,-0.21180894066884262,1.901497527876068,0.28459191556669194 2937 Asymmetric localization of pcp proteins 26 38 3.341018968669272 0.0008347152002925 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,2581,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,-0.9859257988083908,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Regulation of supramolecular fiber organization 29 86 3.33251502965405 0.000860648216872 Q13177,Q14019,P42345,P16949,Q9UQB8,P23396,P59998,Q9BTW9,Q13813,Q08722,P35611,P53367,Q01082,P04350,P61758,P35241,Q9UBN7,Q14203,Q9UHV9,Q07157,Q13045,O75122,P62993,Q92974,P35080,O14786,Q02790,Q9UJU6,Q9NUQ9 Processes and pathways GO Biological process msigdb_gobp 139,140,265,143,18,384,266,163,426,424,287,51,310,305,453,76,80,211,484,479,226,471,236,519,366,118,509,120,128 118,487,860,816,2395,1972,471,1114,1680,305,983,822,823,2604,143,2026,384,1182,1309,366,76,287,1310,2682,265,645,2226,1787,1852,1196,51,1318,266,2759,1254,1319,601,931,453,236,2511,310,509,479,424,1379,2090,226,139,2318,426,697,140,211,786,1863,1010,2093,2447,1698,1699,1706,958,519,755,1505,1957,799,1346,853,1348,163,128,1963,80,1100,1399,484,120,2887,18,1470,1232,2347,1105,1577 1.5705949318057502,0.704699791414857,0.3928095936133701,0.428393191730484,-0.759418488288081,-0.3743938386878874,0.7382358716884349,0.24801958368154803,-0.13234464502495924,0.9671485853633185,0.32091216739564127,0.428393191730484,0.428393191730484,-1.0323962561974658,1.4261935465788533,-0.4158281796670899,0.8375726207273704,0.2111917997668451,0.1367560507410777,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.1367560507410777,-1.1742638113510904,1.0307485270519672,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,-0.2519914877556342,0.2111917997668451,2.237423692928971,0.1367560507410777,1.0307485270519672,-1.3694172456596465,0.17410512476192191,0.1367560507410777,0.6027831121744145,0.35698364577547,0.7715583169098631,1.0935808714347506,-0.8941728675715074,0.9671485853633185,0.704699791414857,0.7382358716884349,0.8046697182564764,0.09914099907683403,-0.4575872142200032,1.1247147016520551,1.455398437788666,-0.6714285051358926,0.8046697182564764,0.5337207971688037,1.455398437788666,1.155663166669387,0.463737560425262,-0.2519914877556342,0.32091216739564127,-0.4575872142200032,-0.8039614683338043,-0.13234464502495924,-0.13234464502495924,-0.13234464502495924,0.35698364577547,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.33327939055474815,0.463737560425262,0.1367560507410777,0.428393191730484,0.1367560507410777,1.33757659471794,1.5420358124097335,-0.33327939055474815,1.901497527876068,0.28459191556669194,0.09914099907683403,0.7382358716884349,1.5705949318057502,-2.0009314909515403,3.7962488360202657,0.0612563185418274,0.2111917997668451,-0.6714285051358926,0.28459191556669194,-0.015336908887356353 2937 Regulation of protein polymerization 21 53 3.3198092579397307 0.0009007897151418 P07900,Q14019,P42345,P16949,Q9UQB8,P23396,P59998,Q9BTW9,Q13813,P35611,Q01082,P04350,P35241,Q14203,P45880,Q13045,P62993,P35080,Q02790,Q9UJU6,Q9NUQ9 Processes and pathways GO Biological process msigdb_gobp 245,140,265,143,18,384,266,163,426,287,310,305,76,211,329,226,236,366,509,120,128 487,860,2395,1114,1680,305,983,245,822,143,384,366,76,287,1310,2682,265,329,645,2226,1787,1852,1196,1318,266,931,236,310,509,1379,226,426,697,140,211,786,1863,1010,2093,2447,1698,958,1505,853,163,128,1963,1100,120,18,1232,2347,1105 0.704699791414857,0.3928095936133701,-0.759418488288081,0.24801958368154803,-0.13234464502495924,0.9671485853633185,0.32091216739564127,1.0622595380909912,0.428393191730484,1.4261935465788533,0.8375726207273704,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.1367560507410777,-1.1742638113510904,1.0307485270519672,0.9350551147231273,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,-0.2519914877556342,0.2111917997668451,0.1367560507410777,1.0307485270519672,0.35698364577547,1.0935808714347506,0.9671485853633185,0.704699791414857,0.09914099907683403,1.1247147016520551,0.8046697182564764,0.5337207971688037,1.455398437788666,1.155663166669387,0.463737560425262,-0.2519914877556342,0.32091216739564127,-0.4575872142200032,-0.8039614683338043,-0.13234464502495924,0.35698364577547,0.02309828334687722,0.428393191730484,1.33757659471794,1.5420358124097335,-0.33327939055474815,0.28459191556669194,1.5705949318057502,3.7962488360202657,0.2111917997668451,-0.6714285051358926,0.28459191556669194 2937 Interleukin 1 signaling 28 45 3.311202002442492 0.0009289612337723 P49720,P45985,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P09429,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,501,876,811,549,149,165,539,578,415,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,1919,165,919,415,362,735,1183,926,1184,1418,876,105,326,327,686,1480,501,539,884,50,198,834,1431,1856,477,1374,1127,1259,1071,2444,890,745,1006,840,201,578,253,549,1460,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,0.8046697182564764,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.704699791414857,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.28459191556669194,-0.8039614683338043,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.0612563185418274,0.463737560425262,0.49884576098804173 2937 Regulation of hmox1 expression and activity 28 46 3.3098622163511737 0.0009334190687424 P49720,P28066,Q9UL46,O00231,Q99460,P09601,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,34,165,539,578,50,840,919,686,926,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,2433,165,919,34,362,1478,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1259,1731,890,745,935,1006,1380,840,201,2189,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.8039614683338043,1.3076973767692464,0.35698364577547,2.871469999732692,0.8702695242261951,0.02309828334687722,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,-0.1719280959561597,0.3928095936133701,0.49884576098804173,0.35698364577547,0.32091216739564127,0.09914099907683403,0.428393191730484,1.1864283685836194,-0.5420991063561916,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Hedgehog ligand biogenesis 26 39 3.30314612319424 0.0009560655455846 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,2503,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1934,1431,1856,477,1374,1127,890,745,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.8941728675715074,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Mapk6 mapk4 signaling 32 47 3.289981904870612 0.0010019382580312 P49720,Q13177,P28066,Q9UL46,P06493,O14980,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q16181,Q13200,P20618,Q9HCE1,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,139,876,811,263,859,549,149,165,539,578,50,840,919,686,560,824,834,201,198,326,327,477,105,890,767,373,745,735,906,362,253 149,1106,560,1353,859,165,919,263,824,362,735,2877,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1254,1856,477,1374,1127,890,139,745,840,201,373,2093,578,253,549,906,1397,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,0.3928095936133701,1.3076973767692464,0.35698364577547,1.0307485270519672,0.428393191730484,0.8702695242261951,0.49884576098804173,-1.9454153738987696,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,0.17410512476192191,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,1.455398437788666,0.49884576098804173,0.428393191730484,1.1864283685836194,0.8702695242261951,-0.4575872142200032,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.3928095936133701,0.09914099907683403,0.463737560425262,0.49884576098804173 2937 Endocytosis 29 94 3.2861121659224497 0.0010158055149522 O00443,Q8N6T3,P15311,P62820,Q8WTV0,Q9NZQ3,Q5VW38,P20645,Q9Y5K6,Q9Y2T2,P09496,O60749,P50897,O15118,P50570,P30533,P35579,P20339,Q9UQ16,Q9H4M9,Q14108,Q99700,O75165,O00429,Q14C86,Q13614,P62993,Q9UJU6,Q00610 Processes and pathways GO Biological process msigdb_gobp 486,401,134,395,10,142,15,25,440,438,535,282,49,173,308,183,63,563,194,340,79,353,220,345,512,110,236,120,508 1039,1969,345,486,1831,173,1970,1471,282,220,2657,1678,1411,732,2261,1413,535,1837,1178,134,681,2825,1362,563,25,2079,828,2128,1247,183,832,63,882,308,49,1597,2085,1125,1728,1599,1254,1791,395,236,1546,1733,1937,508,932,566,2473,1941,1005,110,2270,79,2581,786,512,2092,1898,2448,1270,1271,15,842,2478,401,2649,2916,10,1748,1090,353,1347,1665,1029,714,340,968,1226,142,806,971,120,1878,2297,1672,1289,1167,194,438,440,1105 0.28459191556669194,-0.3743938386878874,0.9027628846125711,0.704699791414857,-0.2519914877556342,1.2776448956782354,-0.3743938386878874,0.02309828334687722,0.9990456262708737,1.1247147016520551,-1.1265583700744997,-0.13234464502495924,0.0612563185418274,0.49884576098804173,-0.6279701240574134,0.0612563185418274,0.6709474376181863,-0.2519914877556342,0.2111917997668451,1.484439279959394,0.5337207971688037,-1.623692476299974,0.09914099907683403,0.6369761233848037,3.2128208825072786,-0.4575872142200032,0.428393191730484,-0.4996758503153541,0.17410512476192191,1.2474172170623723,0.428393191730484,2.085115891068643,0.3928095936133701,0.9671485853633185,2.3364949483641926,-0.05405313922784484,-0.4575872142200032,0.24801958368154803,-0.1719280959561597,-0.05405313922784484,0.17410512476192191,-0.21180894066884262,0.8375726207273704,1.0935808714347506,-0.015336908887356353,-0.1719280959561597,-0.33327939055474815,0.704699791414857,0.35698364577547,0.6369761233848037,-0.8488775839823314,-0.33327939055474815,0.32091216739564127,1.655335720828877,-0.6279701240574134,1.901497527876068,-0.9859257988083908,0.463737560425262,0.704699791414857,-0.4575872142200032,-0.29248013870191797,-0.8039614683338043,0.17410512476192191,0.17410512476192191,3.994138285325319,0.428393191730484,-0.8488775839823314,0.8375726207273704,-1.0792715109109947,-2.589360161351481,4.351275402719301,-0.1719280959561597,0.28459191556669194,0.9027628846125711,0.1367560507410777,-0.09305436959858496,0.32091216739564127,0.5337207971688037,0.9350551147231273,0.35698364577547,0.2111917997668451,1.455398437788666,0.463737560425262,0.35698364577547,1.5705949318057502,-0.2519914877556342,-0.6279701240574134,-0.09305436959858496,0.17410512476192191,0.24801958368154803,1.2170123744522818,0.8046697182564764,0.8046697182564764,0.28459191556669194 2937 Selenoamino acid metabolism 34 90 3.2761670116775887 0.0010522631569402 Q9P2J5,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,P57772,P05387,P07814,P08865,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,Q16881,P62829,Q9Y3U8,P62847,P35268,P46782,P46779,P62241 Processes and pathways Reactome Pathways msigdb_reactome 668,136,504,505,506,384,387,389,155,650,649,289,423,542,309,562,679,680,682,454,82,83,325,225,95,604,100,607,243,372,367,599,738,743 2168,1632,1587,2603,562,1638,679,1414,680,1843,1530,682,874,1477,384,1533,1245,325,1419,1644,1931,367,1311,82,387,1645,1062,95,389,1189,737,738,1482,599,155,883,1314,927,1193,1933,1317,1688,309,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,1131,1261,1327,1694,100,668,243 -0.5420991063561916,-0.09305436959858496,-0.05405313922784484,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.5337207971688037,0.0612563185418274,0.5337207971688037,-0.2519914877556342,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,-0.015336908887356353,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,0.28459191556669194,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.3928095936133701,0.1367560507410777,0.35698364577547,0.2111917997668451,-0.33327939055474815,0.1367560507410777,-0.13234464502495924,0.9671485853633185,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,0.17410512476192191,0.1367560507410777,-0.13234464502495924,1.7110652769447776,0.5683656165997513,1.0935808714347506 2937 Fceri mediated nf kb activation 26 41 3.258933224230546 0.0011183198679725 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,1919,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1259,2444,890,745,1006,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,-0.8039614683338043,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Dectin 1 mediated noncanonical nf kb signaling 28 42 3.258505115795488 0.001120008569527 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,Q8TBC4,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,926,560,834,201,198,326,327,1017,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1935,1856,477,1374,1127,1259,2444,890,745,1006,840,201,1017,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.33327939055474815,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,-0.8039614683338043,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.32091216739564127,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Response of eif2ak4 gcn2 to amino acid deficiency 38 77 3.256752182537719 0.0011269477486195 P46778,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P20042,P83881,P62750,P61353,Q92616,P08243,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P62861,P42766,P61927,P05198,P62829,Q9Y3U8,P62847,P35268,P62269,P46782,P62910,P46779,P62241 Processes and pathways Reactome Pathways msigdb_reactome 737,136,504,505,506,384,387,389,155,650,649,773,289,423,542,315,307,562,680,682,835,454,82,83,325,225,95,604,594,607,243,372,367,887,599,888,738,743 594,2603,562,1638,307,1414,680,1530,682,874,1477,773,384,1245,325,1419,1644,1931,367,1311,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,1933,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,1131,315,243 0.6027831121744145,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.9671485853633185,0.0612563185418274,0.5337207971688037,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.463737560425262,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,0.9671485853633185,1.0935808714347506 2937 Signaling by hedgehog 32 54 3.256000271414963 0.0011299364349512 P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P04350,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q13885,P17980,Q13200,P20618,Q9Y496,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,502,876,811,549,149,165,539,578,50,840,919,305,686,560,824,834,201,198,326,327,477,832,105,890,767,747,362,745,735,259,253 149,1106,560,1353,165,919,305,2503,1306,1641,824,362,735,1183,926,1184,1418,876,105,326,327,832,686,1480,539,502,884,50,1251,198,834,1934,1431,1856,477,1374,1127,1259,890,745,1006,1380,747,840,201,2326,578,253,549,1568,1153,811,767,259 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.9671485853633185,-0.8941728675715074,0.1367560507410777,-0.09305436959858496,0.428393191730484,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.704699791414857,0.3928095936133701,2.237423692928971,0.17410512476192191,1.1864283685836194,0.428393191730484,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.09914099907683403,0.49884576098804173,0.428393191730484,1.1864283685836194,-0.6714285051358926,0.6369761233848037,1.0622595380909912,0.6709474376181863,-0.015336908887356353,0.24801958368154803,0.463737560425262,0.49884576098804173,1.0622595380909912 2937 Polymeric cytoskeletal fiber 43 153 3.2494456836105456 0.0011563015813109 P46940,Q9BSJ2,P15311,P27816,Q14019,Q9Y6G9,Q9NZQ3,P16949,Q9UQB8,P06493,Q9H6D7,Q9BTW9,Q9Y5K6,P07197,Q14152,P08670,Q13409,P50570,P04350,O43237,Q9UQ16,Q9HC35,Q14204,Q9UBN7,P50402,Q14203,Q9UPN3,Q6SZW1,Q9H0B6,P33176,Q96EY1,O75122,O00429,Q15555,Q9Y496,Q96CW5,Q53GG5,Q92974,Q02790,O14786,Q9UJU6,Q9Y266,Q00610 Localization GO Cellular component msigdb_gocc 131,403,134,497,140,280,142,143,18,263,164,163,440,157,180,414,311,308,305,182,194,341,332,80,330,211,485,87,92,473,352,471,345,348,259,376,516,519,509,118,120,121,508 1968,725,1041,345,118,1767,816,182,2018,589,863,978,1883,471,728,592,1302,1115,2220,980,1473,305,263,2070,157,1057,414,870,771,2806,2075,134,1179,143,734,1307,1182,497,1309,473,2682,1846,1367,1313,1064,645,131,1250,600,502,1191,330,308,1426,1252,648,1484,2826,742,2511,2136,1260,1937,508,1796,2607,509,933,1074,2412,1379,1604,311,895,1380,747,697,140,180,938,211,332,786,1897,2794,1863,940,2184,1202,348,1010,1267,2851,2668,2093,1898,2447,943,516,1272,1494,87,2046,1807,2275,1950,2764,1706,1811,1453,519,376,1616,352,1213,2283,1152,1022,2106,1456,1348,403,163,1568,1153,1667,92,2290,164,341,1757,2387,142,718,1285,805,80,1400,1516,120,2887,1672,485,194,18,121,2347,259,1294,440,1520,1763,280 -0.3743938386878874,0.49884576098804173,0.28459191556669194,0.9027628846125711,1.5705949318057502,-0.21180894066884262,0.428393191730484,1.2474172170623723,-0.4158281796670899,0.6027831121744145,0.3928095936133701,0.32091216739564127,-0.29248013870191797,0.7382358716884349,0.49884576098804173,0.6027831121744145,0.1367560507410777,0.24801958368154803,-0.5848621144923504,0.32091216739564127,0.02309828334687722,0.9671485853633185,1.0307485270519672,-0.4575872142200032,1.33757659471794,0.28459191556669194,0.8046697182564764,0.3928095936133701,0.463737560425262,-1.5205468840168608,-0.4575872142200032,1.484439279959394,0.2111917997668451,1.4261935465788533,0.49884576098804173,0.1367560507410777,0.2111917997668451,0.704699791414857,0.1367560507410777,0.7382358716884349,-1.1742638113510904,-0.2519914877556342,0.09914099907683403,0.1367560507410777,0.28459191556669194,0.5683656165997513,1.5133178288044788,0.17410512476192191,0.6027831121744145,0.704699791414857,0.2111917997668451,0.9350551147231273,0.9671485853633185,0.0612563185418274,0.17410512476192191,0.5683656165997513,0.02309828334687722,-1.623692476299974,0.49884576098804173,-0.8941728675715074,-0.4996758503153541,0.17410512476192191,-0.33327939055474815,0.704699791414857,-0.21180894066884262,-1.0323962561974658,0.704699791414857,0.35698364577547,0.28459191556669194,-0.759418488288081,0.09914099907683403,-0.05405313922784484,0.9671485853633185,0.3928095936133701,0.09914099907683403,0.49884576098804173,0.5337207971688037,1.455398437788666,1.2776448956782354,0.35698364577547,1.155663166669387,0.9350551147231273,0.463737560425262,-0.29248013870191797,-1.469700408349865,-0.2519914877556342,0.35698364577547,-0.5420991063561916,0.2111917997668451,0.9027628846125711,0.32091216739564127,0.17410512476192191,-1.7288348009106087,-1.1265583700744997,-0.4575872142200032,-0.29248013870191797,-0.8039614683338043,0.35698364577547,0.704699791414857,0.17410512476192191,0.02309828334687722,1.8478045517497095,-0.4158281796670899,-0.21180894066884262,-0.6279701240574134,-0.33327939055474815,-1.3694172456596465,-0.13234464502495924,-0.21180894066884262,0.0612563185418274,0.704699791414857,0.8702695242261951,-0.05405313922784484,0.9027628846125711,0.2111917997668451,-0.6279701240574134,0.24801958368154803,0.32091216739564127,-0.4575872142200032,0.0612563185418274,0.1367560507410777,0.8375726207273704,1.33757659471794,-0.015336908887356353,0.24801958368154803,-0.09305436959858496,1.8207460887469624,-0.6279701240574134,1.33757659471794,0.9350551147231273,-0.1719280959561597,-0.7152427522665485,1.455398437788666,0.5337207971688037,0.17410512476192191,0.463737560425262,1.901497527876068,0.09914099907683403,0.02309828334687722,1.5705949318057502,-2.0009314909515403,-0.09305436959858496,0.7382358716884349,1.2170123744522818,3.7962488360202657,1.5705949318057502,-0.6714285051358926,1.0622595380909912,0.17410512476192191,0.8046697182564764,0.02309828334687722,-0.1719280959561597,1.0307485270519672 2937 Regulation of ras by gaps 26 40 3.2461291910573915 0.0011698573806022 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,165,919,2502,362,735,2178,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,890,745,1380,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.8941728675715074,0.8702695242261951,0.49884576098804173,-0.5420991063561916,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.09914099907683403,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Organophosphate catabolic process 8 33 3.188610740819707 0.0014295824068664 Q9H773,Q8WTV0,Q8NCC3,O43598,Q13614,Q10713,Q6SZW1,P35610 Processes and pathways GO Biological process msigdb_gobp 1,10,12,108,110,179,87,154 1040,108,1585,1637,2172,1681,1589,1682,234,2831,1592,879,154,1850,1892,1934,1858,179,110,87,2691,2003,2618,12,10,2886,433,1957,1908,1,2158,670,558 0.28459191556669194,1.655335720828877,-0.05405313922784484,-0.09305436959858496,-0.5420991063561916,-0.13234464502495924,-0.05405313922784484,-0.13234464502495924,1.0935808714347506,-1.6760094336606017,-0.05405313922784484,0.3928095936133701,1.3672844525092513,-0.2519914877556342,-0.29248013870191797,-0.33327939055474815,-0.2519914877556342,1.2776448956782354,1.655335720828877,1.8478045517497095,-1.1742638113510904,-0.3743938386878874,-1.0323962561974658,4.268556610395897,4.351275402719301,-2.0009314909515403,0.8046697182564764,-0.33327939055474815,-0.29248013870191797,5.8748316084197345,-0.4996758503153541,0.5683656165997513,0.6709474376181863 2937 Apical plasma membrane 9 35 3.1842586453498525 0.0014512527699341 P08183,P15311,P35241,P26038,Q9Y4G8,Q9Y6M7,O95342,P08238,P53985 Localization GO Cellular component msigdb_gocc 8,134,76,176,61,148,22,306,161 2801,1108,2657,22,1473,2069,8,984,1177,306,2353,1841,134,2077,1244,176,1928,76,2082,1685,1479,1125,161,1987,1429,1989,1002,1329,373,1083,1709,1564,1911,61,148 -1.5205468840168608,0.24801958368154803,-1.1265583700744997,3.513047173839545,0.02309828334687722,-0.4575872142200032,4.383977831042348,0.32091216739564127,0.2111917997668451,0.9671485853633185,-0.7152427522665485,-0.2519914877556342,1.484439279959394,-0.4575872142200032,0.17410512476192191,1.2776448956782354,-0.33327939055474815,1.9281348523770536,-0.4575872142200032,-0.13234464502495924,0.02309828334687722,0.24801958368154803,1.33757659471794,-0.3743938386878874,0.0612563185418274,-0.3743938386878874,0.32091216739564127,0.1367560507410777,0.8702695242261951,0.28459191556669194,-0.13234464502495924,-0.015336908887356353,-0.29248013870191797,2.1108177774831414,1.4261935465788533 2937 Endopeptidase complex 39 52 3.17998815889092 0.0014728107043102 P49720,P54578,P62333,Q5VYK3,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q9Y5K5,Q92530,P49721,Q14997,P17655,O75832,P25788,O43396,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P54727,Q9H490,P28070,Q16186,Q9UNM6,Q06323,Q13200,P20618,O00232,P04632,P17980,Q99436 Localization GO Cellular component msigdb_gocc 884,998,1127,270,876,811,549,149,165,539,1233,578,50,840,1180,919,1184,1043,686,926,560,834,201,198,326,327,477,224,1156,105,515,767,890,745,735,1106,982,362,253 149,1106,560,1353,165,1882,1043,919,982,1180,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,998,224,834,1934,1431,1856,477,1374,1127,890,745,840,201,1441,515,270,578,1387,2196,1343,253,549,1156,811,767,1233 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,-0.29248013870191797,0.28459191556669194,0.35698364577547,0.32091216739564127,0.2111917997668451,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.32091216739564127,1.1247147016520551,0.428393191730484,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.0612563185418274,0.704699791414857,1.0307485270519672,0.6369761233848037,0.09914099907683403,-0.5420991063561916,0.1367560507410777,1.0622595380909912,0.6709474376181863,0.24801958368154803,0.463737560425262,0.49884576098804173,0.2111917997668451 2937 Regulation of cell projection organization 34 104 3.163477937786657 0.0015589616730973 O15144,P15311,Q9Y639,P27816,Q13177,Q9NR77,Q9NZQ3,P42345,P42858,Q9UQB8,Q14444,P08670,Q96QK1,P50570,Q9Y4G8,P20339,Q9UQ16,P78344,Q06787,Q9H4M9,Q4KMP7,P35241,Q14108,Q9UPN3,Q6SZW1,Q15555,Q9P265,Q16181,P35080,O14786,Q9NT62,Q9UJU6,Q02790,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 487,134,408,497,139,13,142,265,144,18,428,414,581,308,61,563,194,68,566,340,613,76,79,485,87,348,242,373,366,118,257,120,509,526 118,1831,487,1921,2802,1114,983,414,2437,134,563,2026,1364,1182,1119,497,777,366,76,265,144,1064,2084,645,1787,1251,1195,308,1371,1789,1254,2360,1067,931,68,1733,1937,1071,509,889,566,1379,1199,139,1003,1605,79,938,428,1897,2092,1333,348,2512,373,2093,2447,2040,1268,613,793,87,2046,1698,1142,706,1014,1016,2482,2194,2796,2485,1213,581,1348,2829,1755,340,906,526,1224,13,257,1757,1758,2733,142,805,242,1400,120,1761,2297,631,2594,485,194,18,2250,2347,975,914,61,408 1.5705949318057502,-0.2519914877556342,0.704699791414857,-0.33327939055474815,-1.5205468840168608,0.24801958368154803,0.32091216739564127,0.8046697182564764,-0.8039614683338043,1.484439279959394,0.6369761233848037,-0.4158281796670899,0.09914099907683403,0.2111917997668451,0.24801958368154803,0.704699791414857,0.463737560425262,0.8702695242261951,1.9281348523770536,1.0307485270519672,1.4261935465788533,0.28459191556669194,-0.4575872142200032,0.5683656165997513,-0.21180894066884262,0.17410512476192191,0.2111917997668451,0.9671485853633185,0.09914099907683403,-0.21180894066884262,0.17410512476192191,-0.7152427522665485,0.28459191556669194,0.35698364577547,2.0333215775625626,-0.1719280959561597,-0.33327939055474815,0.28459191556669194,0.704699791414857,0.3928095936133701,0.6369761233848037,0.09914099907683403,0.2111917997668451,1.455398437788666,0.32091216739564127,-0.05405313922784484,1.901497527876068,0.35698364577547,0.8046697182564764,-0.29248013870191797,-0.4575872142200032,0.1367560507410777,0.9027628846125711,-0.8941728675715074,0.8702695242261951,-0.4575872142200032,-0.8039614683338043,-0.4158281796670899,0.17410512476192191,0.6027831121744145,0.463737560425262,1.8478045517497095,-0.4158281796670899,-0.13234464502495924,0.24801958368154803,0.5337207971688037,0.32091216739564127,0.32091216739564127,-0.8488775839823314,-0.5420991063561916,-1.469700408349865,-0.8488775839823314,0.2111917997668451,0.6369761233848037,0.1367560507410777,-1.623692476299974,-0.1719280959561597,0.9350551147231273,0.3928095936133701,0.704699791414857,0.2111917997668451,4.2518449635579465,1.0622595380909912,-0.1719280959561597,-0.1719280959561597,-1.2709592380232988,1.455398437788666,0.463737560425262,1.0935808714347506,0.09914099907683403,1.5705949318057502,-0.1719280959561597,-0.6279701240574134,0.6027831121744145,-0.9859257988083908,0.7382358716884349,1.2170123744522818,3.7962488360202657,-0.5848621144923504,-0.6714285051358926,0.35698364577547,0.3928095936133701,2.1108177774831414,0.8375726207273704 2937 Clec7a dectin 1 signaling 28 43 3.161170357260388 0.001571365666888 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,Q8TBC4,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,926,560,834,201,198,326,327,1017,477,105,890,767,745,735,362,253 149,1106,560,1353,1919,165,919,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1935,1856,477,1374,1127,1259,2444,890,745,1006,840,201,1017,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.33327939055474815,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,-0.8039614683338043,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.32091216739564127,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Blood vessel endothelial cell migration 6 21 3.150706072836136 0.0016287631109013 P09601,P42785,Q8WTV0,P06576,O14786,P35579 Processes and pathways GO Biological process msigdb_gobp 34,6,10,196,118,63 486,118,1114,1473,2261,196,415,34,2075,234,2178,2080,63,6,1852,931,1731,1011,943,1270,10 0.704699791414857,1.5705949318057502,0.24801958368154803,0.02309828334687722,-0.6279701240574134,1.1864283685836194,0.8046697182564764,2.871469999732692,-0.4575872142200032,1.0935808714347506,-0.5420991063561916,-0.4575872142200032,2.085115891068643,4.496753993926139,-0.2519914877556342,0.35698364577547,-0.1719280959561597,0.32091216739564127,0.35698364577547,0.17410512476192191,4.351275402719301 2937 serine protease 6 16 3.1491808110333896 0.00163728858826 Q4J6C6,O14773,P42785,Q9H3G5,Q9HB40,P13798 Functions Panther Protein class panther_protein_class 33,129,6,17,55,208 129,2073,1839,208,2028,687,6,1594,1375,237,33,2275,2003,17,55,2159 1.5133178288044788,-0.4575872142200032,-0.2519914877556342,1.155663166669387,-0.4158281796670899,0.5337207971688037,4.496753993926139,-0.05405313922784484,0.09914099907683403,1.0935808714347506,2.959000560087587,-0.6279701240574134,-0.3743938386878874,3.7962488360202657,2.1871572148884817,-0.4996758503153541 2937 Apc c mediated degradation of cell cycle proteins 33 56 3.144680987217607 0.0016626802956449 P14635,P49720,P28066,Q9UJX3,Q9UL46,P06493,Q99460,O00231,P24941,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P30260,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q16763 Processes and pathways Reactome Pathways msigdb_reactome 873,884,876,810,811,263,549,149,775,165,539,578,50,840,919,686,926,560,834,201,198,326,327,829,477,105,890,767,745,735,362,253,126 149,1106,560,1353,1767,165,2064,2216,919,263,873,362,735,775,1183,926,1184,1418,876,105,326,327,829,686,1480,539,884,50,198,1484,834,1431,1856,477,1374,1127,1259,890,1199,745,935,1006,840,201,126,578,2425,253,549,1571,2388,810,1760,1574,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.21180894066884262,1.3076973767692464,-0.4575872142200032,-0.5848621144923504,0.35698364577547,1.0307485270519672,0.3928095936133701,0.8702695242261951,0.49884576098804173,0.463737560425262,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.02309828334687722,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.2111917997668451,0.49884576098804173,0.35698364577547,0.32091216739564127,0.428393191730484,1.1864283685836194,1.5420358124097335,0.6369761233848037,-0.759418488288081,1.0622595380909912,0.6709474376181863,-0.015336908887356353,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,0.463737560425262,0.49884576098804173 2937 Ficolin 1 rich granule lumen 39 71 3.13666180796856 0.0017088311439035 P14174,P09960,P07900,Q14019,P35573,O00231,Q96G03,Q86VP6,P53396,P06737,O43242,Q13442,P09429,P08238,P35998,Q9NZ32,O00487,P18669,Q14004,Q15008,P37108,P51665,P06744,P0DMV9,P11142,P42025,P18206,P13798,Q7Z6Z7,P13639,Q9UNM6,Q13200,P46976,P20618,P12956,Q9UJU6,P17980,Q99436,Q13510 Localization GO Cellular component msigdb_gocc 122,868,245,140,880,149,433,296,782,534,165,46,415,306,686,855,560,683,569,201,688,198,324,822,823,689,209,208,752,872,767,745,235,735,233,120,362,253,397 149,1106,560,1721,165,1585,1359,2172,1836,1055,534,324,1474,245,306,415,868,2403,822,823,1840,233,872,208,122,987,2075,2354,1724,1889,362,209,683,735,1725,926,876,1247,880,686,1423,688,689,235,1426,198,782,1934,1067,1731,2638,2317,1200,745,46,397,569,140,1693,201,1011,752,296,433,253,1027,855,1573,120,767,2673 1.3968228224013606,0.24801958368154803,0.6369761233848037,-0.1719280959561597,1.3076973767692464,-0.05405313922784484,0.09914099907683403,-0.5420991063561916,-0.2519914877556342,0.28459191556669194,0.6709474376181863,0.9350551147231273,0.02309828334687722,1.0622595380909912,0.9671485853633185,0.8046697182564764,0.3928095936133701,-0.759418488288081,0.428393191730484,0.428393191730484,-0.2519914877556342,1.0935808714347506,0.3928095936133701,1.155663166669387,1.5420358124097335,0.32091216739564127,-0.4575872142200032,-0.7152427522665485,-0.1719280959561597,-0.29248013870191797,0.8702695242261951,1.155663166669387,0.5337207971688037,0.49884576098804173,-0.1719280959561597,0.35698364577547,0.3928095936133701,0.17410512476192191,0.3928095936133701,0.5337207971688037,0.0612563185418274,0.5337207971688037,0.5337207971688037,1.0935808714347506,0.0612563185418274,1.1864283685836194,0.463737560425262,-0.33327939055474815,0.28459191556669194,-0.1719280959561597,-1.0792715109109947,-0.6714285051358926,0.2111917997668451,0.49884576098804173,2.4815800828960706,0.8375726207273704,0.6369761233848037,1.455398437788666,-0.13234464502495924,1.1864283685836194,0.32091216739564127,0.49884576098804173,0.9990456262708737,0.8046697182564764,1.0622595380909912,0.32091216739564127,0.428393191730484,-0.015336908887356353,1.5705949318057502,0.49884576098804173,-1.1265583700744997 2937 Actin filament organization 28 98 3.129055281462042 0.0017536931154034 O15144,P15311,Q13177,Q14019,P42345,P16949,Q9UQB8,P59998,Q96JJ3,Q9Y5K6,Q13813,Q08722,P35611,P53367,Q01082,Q05682,Q15942,P35241,Q07157,Q13045,O75122,P62993,Q92974,P35080,O14786,Q9UJU6,Q9NUQ9,Q68EM7 Processes and pathways GO Biological process msigdb_gobp 487,134,139,140,265,143,18,266,434,440,426,424,287,51,310,59,203,76,479,226,471,236,519,366,118,120,128,251 725,1041,1969,118,487,860,2395,978,488,1972,471,1114,2024,1680,1836,2261,2070,983,870,2806,2604,1842,134,143,2026,1364,1643,366,1121,76,287,265,2226,1787,1849,1196,51,2086,1318,266,2759,1254,1319,601,2360,1067,931,236,2511,2136,1733,310,59,479,424,1379,226,139,545,1380,426,140,938,786,1897,1202,203,2093,2447,2040,251,950,1698,660,2619,958,519,755,1505,1957,434,853,1348,1623,128,1963,1100,1399,120,2594,1672,18,1470,2347,1294,440,1105,1577 0.49884576098804173,0.28459191556669194,-0.3743938386878874,1.5705949318057502,0.704699791414857,0.3928095936133701,-0.759418488288081,0.32091216739564127,0.704699791414857,-0.3743938386878874,0.7382358716884349,0.24801958368154803,-0.4158281796670899,-0.13234464502495924,-0.2519914877556342,-0.6279701240574134,-0.4575872142200032,0.32091216739564127,0.3928095936133701,-1.5205468840168608,-1.0323962561974658,-0.2519914877556342,1.484439279959394,1.4261935465788533,-0.4158281796670899,0.09914099907683403,-0.09305436959858496,0.8702695242261951,0.24801958368154803,1.9281348523770536,0.9990456262708737,1.0307485270519672,-0.5848621144923504,-0.21180894066884262,-0.2519914877556342,0.2111917997668451,2.237423692928971,-0.4575872142200032,0.1367560507410777,1.0307485270519672,-1.3694172456596465,0.17410512476192191,0.1367560507410777,0.6027831121744145,-0.7152427522665485,0.28459191556669194,0.35698364577547,1.0935808714347506,-0.8941728675715074,-0.4996758503153541,-0.1719280959561597,0.9671485853633185,2.1363911463999377,0.7382358716884349,0.8046697182564764,0.09914099907683403,1.1247147016520551,1.455398437788666,0.6709474376181863,0.09914099907683403,0.8046697182564764,1.455398437788666,0.35698364577547,0.463737560425262,-0.29248013870191797,0.2111917997668451,1.1864283685836194,-0.4575872142200032,-0.8039614683338043,-0.4158281796670899,1.0622595380909912,0.35698364577547,-0.13234464502495924,0.5683656165997513,-1.0323962561974658,0.35698364577547,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.33327939055474815,0.8046697182564764,0.428393191730484,0.1367560507410777,-0.05405313922784484,1.5420358124097335,-0.33327939055474815,0.28459191556669194,0.09914099907683403,1.5705949318057502,-0.9859257988083908,-0.09305436959858496,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.17410512476192191,0.8046697182564764,0.28459191556669194,-0.015336908887356353 2937 Actin filament polymerization 14 37 3.128543351074088 0.0017567509432729 O15144,Q13813,Q14019,P35611,P42345,P35241,P62993,Q9UQB8,P35080,P59998,Q01082,Q9NUQ9,Q9UJU6,Q13045 Processes and pathways GO Biological process msigdb_gobp 487,426,140,287,265,76,236,18,366,266,310,128,120,226 487,860,2395,488,1114,1680,983,366,76,287,265,2226,1787,1196,2086,1318,266,931,236,310,1379,226,426,140,786,2447,1698,958,1505,853,1623,128,1100,120,18,2347,1105 0.704699791414857,0.3928095936133701,-0.759418488288081,0.704699791414857,0.24801958368154803,-0.13234464502495924,0.32091216739564127,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,-0.4575872142200032,0.1367560507410777,1.0307485270519672,0.35698364577547,1.0935808714347506,0.9671485853633185,0.09914099907683403,1.1247147016520551,0.8046697182564764,1.455398437788666,0.463737560425262,-0.8039614683338043,-0.13234464502495924,0.35698364577547,0.02309828334687722,0.428393191730484,-0.05405313922784484,1.5420358124097335,0.28459191556669194,1.5705949318057502,3.7962488360202657,-0.6714285051358926,0.28459191556669194 2937 Serine hydrolase activity 6 18 3.121099314618707 0.0018017725812233 Q4J6C6,O14773,P42785,Q9H3G5,Q9HB40,P13798 Functions GO Molecular function msigdb_gomf 33,129,6,17,55,208 129,1775,2073,208,2028,687,6,1594,2407,997,1375,237,33,459,1557,2275,17,55 1.5133178288044788,-0.21180894066884262,-0.4575872142200032,1.155663166669387,-0.4158281796670899,0.5337207971688037,4.496753993926139,-0.05405313922784484,-0.759418488288081,0.32091216739564127,0.09914099907683403,1.0935808714347506,2.959000560087587,0.7715583169098631,-0.015336908887356353,-0.6279701240574134,3.7962488360202657,2.1871572148884817 2937 Regulation of cellular protein catabolic process 43 79 3.120719097488952 0.0018041003589508 P07900,Q6ZXV5,P15311,P54578,P48729,P62081,Q9UL46,O14980,P48506,Q9Y5A7,P24941,Q92530,P26038,Q8N163,O60826,Q96QK1,Q15370,O75832,P08238,P35998,O00487,Q92990,Q06787,P17612,P35241,P0DMV9,P60520,Q96KB5,P61086,P62191,P54727,Q9H2J4,P62829,Q06323,Q9UNN5,Q9GZP4,O75150,Q9ULT8,O95376,P46379,P04062,P17980,O15372 Processes and pathways GO Biological process msigdb_gobp 245,794,134,998,502,505,811,859,779,559,775,578,176,845,175,581,572,919,306,686,560,335,566,824,76,822,691,1021,452,477,224,761,607,890,912,905,727,910,731,114,981,362,862 2120,560,1767,859,1581,862,2213,175,727,919,1586,1357,731,1115,981,1413,245,306,822,1529,134,824,362,1478,775,176,76,686,1480,1481,114,1189,779,502,1251,1124,1484,997,998,224,1934,691,452,1856,505,477,1374,1127,607,1545,1793,890,566,1199,572,794,1950,845,578,1904,335,1388,2333,2283,1021,581,1346,905,761,2205,1825,1761,811,910,1102,912,1762,559,1233 -0.4996758503153541,0.6369761233848037,-0.21180894066884262,0.3928095936133701,-0.05405313922784484,0.3928095936133701,-0.5848621144923504,1.2776448956782354,0.49884576098804173,0.35698364577547,-0.05405313922784484,0.09914099907683403,0.49884576098804173,0.24801958368154803,0.32091216739564127,0.0612563185418274,1.0622595380909912,0.9671485853633185,0.428393191730484,-0.015336908887356353,1.484439279959394,0.428393191730484,0.8702695242261951,0.02309828334687722,0.463737560425262,1.2776448956782354,1.9281348523770536,0.5337207971688037,0.02309828334687722,0.02309828334687722,1.627243250148423,0.2111917997668451,0.463737560425262,0.704699791414857,0.17410512476192191,0.24801958368154803,0.02309828334687722,0.32091216739564127,0.32091216739564127,1.1247147016520551,-0.33327939055474815,0.5337207971688037,0.7715583169098631,-0.2519914877556342,0.704699791414857,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.6027831121744145,-0.015336908887356353,-0.21180894066884262,0.3928095936133701,0.6369761233848037,0.2111917997668451,0.6369761233848037,0.463737560425262,-0.33327939055474815,0.428393191730484,0.6369761233848037,-0.29248013870191797,0.9350551147231273,0.09914099907683403,-0.6714285051358926,-0.6279701240574134,0.32091216739564127,0.6369761233848037,0.1367560507410777,0.3928095936133701,0.49884576098804173,-0.5420991063561916,-0.21180894066884262,-0.1719280959561597,0.463737560425262,0.3928095936133701,0.28459191556669194,0.3928095936133701,-0.1719280959561597,0.6709474376181863,0.2111917997668451 2937 Phospholipid binding 26 75 3.115262313914283 0.0018378139568433 O00443,O14773,P46940,Q8WTV0,Q8NCC3,P37198,P07602,Q13576,O60749,P48739,P09429,P50897,P53367,Q01082,Q9Y4G8,Q00169,Q9UJY4,Q9UNH7,Q14108,P20073,P45880,Q99829,Q13045,P21796,Q53T59,P35080 Functions GO Molecular function msigdb_gomf 486,129,131,10,12,386,151,545,282,540,415,49,51,310,61,455,466,343,79,448,329,482,226,99,238,366 1039,1969,486,129,1581,1882,978,1883,2802,282,637,1473,1413,151,983,2174,415,823,1780,448,2178,99,1059,2355,877,366,386,329,645,131,540,49,1065,51,455,310,1379,226,1941,545,1005,79,1863,1554,238,2478,1743,753,12,2872,10,579,1387,755,482,853,2241,2456,2243,1156,763,1161,2734,806,466,909,1878,1289,1167,343,1290,723,61,2299,1105 0.28459191556669194,-0.3743938386878874,0.704699791414857,1.5133178288044788,-0.05405313922784484,-0.29248013870191797,0.32091216739564127,-0.29248013870191797,-1.5205468840168608,0.9990456262708737,0.5683656165997513,0.02309828334687722,0.0612563185418274,1.3968228224013606,0.32091216739564127,-0.5420991063561916,0.8046697182564764,0.428393191730484,-0.21180894066884262,0.7715583169098631,-0.5420991063561916,1.7110652769447776,0.28459191556669194,-0.7152427522665485,0.3928095936133701,0.8702695242261951,0.8375726207273704,0.9350551147231273,0.5683656165997513,1.5133178288044788,0.6709474376181863,2.3364949483641926,0.28459191556669194,2.237423692928971,0.7715583169098631,0.9671485853633185,0.09914099907683403,1.1247147016520551,-0.33327939055474815,0.6709474376181863,0.32091216739564127,1.901497527876068,-0.2519914877556342,-0.015336908887356353,1.0935808714347506,-0.8488775839823314,-0.1719280959561597,0.49884576098804173,4.268556610395897,-1.8904581760074333,4.351275402719301,0.6369761233848037,0.09914099907683403,0.49884576098804173,0.7382358716884349,0.428393191730484,-0.5848621144923504,-0.8039614683338043,-0.5848621144923504,0.24801958368154803,0.49884576098804173,0.24801958368154803,-1.2709592380232988,0.463737560425262,0.7715583169098631,0.3928095936133701,-0.2519914877556342,0.17410512476192191,0.24801958368154803,0.9350551147231273,0.17410512476192191,0.5337207971688037,2.1108177774831414,-0.6279701240574134,0.28459191556669194 2937 centrosome 18 29 3.0985454879724887 0.0019447311355589 Q13561,P33176,P17612,P33981,Q9Y6G9,Q13442,P48729,Q14204,Q10713,Q14008,P31946,P06493,P62258,P27348,Q13409,P63104,Q9H0B6,O43237 Localization OpenCell Localization opencell_localization 895,473,824,499,280,46,502,332,179,697,385,263,692,827,311,507,92,182 1108,182,1412,1176,263,824,1182,827,385,473,499,502,1484,1255,692,507,889,1074,179,311,46,895,697,332,1010,1706,2106,92,280 0.24801958368154803,1.2474172170623723,0.0612563185418274,0.2111917997668451,1.0307485270519672,0.428393191730484,0.2111917997668451,0.428393191730484,0.8375726207273704,0.7382358716884349,0.704699791414857,0.704699791414857,0.02309828334687722,0.17410512476192191,0.5337207971688037,0.704699791414857,0.3928095936133701,0.28459191556669194,1.2776448956782354,0.9671485853633185,2.4815800828960706,0.3928095936133701,0.5337207971688037,0.9350551147231273,0.32091216739564127,-0.13234464502495924,-0.4575872142200032,1.8207460887469624,1.0307485270519672 2937 Negative regulation of protein polymerization 11 22 3.09298468779816 0.0019815435913468 P45880,Q13813,P35241,P35611,P16949,P35080,Q01082,Q9NUQ9,P04350,Q13045,Q9BTW9 Processes and pathways GO Biological process msigdb_gobp 329,426,76,287,143,366,310,128,305,226,163 1114,305,983,143,366,76,287,329,2226,1787,1196,1318,310,509,1379,226,426,1010,853,163,128,1100 0.24801958368154803,0.9671485853633185,0.32091216739564127,1.4261935465788533,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.9350551147231273,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,0.1367560507410777,0.9671485853633185,0.704699791414857,0.09914099907683403,1.1247147016520551,0.8046697182564764,0.32091216739564127,0.428393191730484,1.33757659471794,1.5420358124097335,0.28459191556669194 2937 G2 m checkpoints 46 85 3.083046112598596 0.0020489340315221 P33991,P14635,P49720,P28066,P27694,Q9UL46,P06493,P31946,Q99460,O00231,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,Q14997,O75832,P35998,O60921,O00487,P55036,Q15819,Q15008,P51665,O95714,P62258,P35244,P49736,P27348,P28072,P28074,P62191,P25205,Q04917,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,P63104 Processes and pathways Reactome Pathways msigdb_reactome 246,873,884,876,875,811,263,385,549,149,775,778,537,165,290,781,539,578,50,840,919,686,304,560,834,611,201,198,820,692,450,690,827,326,327,477,826,889,105,890,767,745,735,362,253,507 149,1106,560,1353,165,1113,304,1923,919,1679,820,1053,2544,2025,263,873,1888,362,735,775,826,1183,926,1184,1418,827,875,876,105,326,327,385,246,778,537,450,2131,1534,686,2356,2507,2222,1480,539,884,50,690,1596,781,198,1687,834,1431,1856,1255,477,1374,692,1127,1690,507,889,890,2446,745,290,2368,840,201,611,578,1275,253,549,1215,1393,1225,1514,2387,1467,811,767,1351,1518,2392 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.24801958368154803,0.9671485853633185,-0.33327939055474815,0.35698364577547,-0.13234464502495924,0.428393191730484,0.28459191556669194,-0.9398534966833773,-0.4158281796670899,1.0307485270519672,0.3928095936133701,-0.29248013870191797,0.8702695242261951,0.49884576098804173,0.463737560425262,0.428393191730484,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.428393191730484,0.3928095936133701,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.8375726207273704,1.0622595380909912,0.463737560425262,0.6709474376181863,0.7715583169098631,-0.4996758503153541,-0.015336908887356353,0.5337207971688037,-0.7152427522665485,-0.8941728675715074,-0.5848621144923504,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,0.5337207971688037,-0.05405313922784484,0.463737560425262,1.1864283685836194,-0.13234464502495924,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.17410512476192191,0.7382358716884349,0.09914099907683403,0.5337207971688037,0.24801958368154803,-0.13234464502495924,0.704699791414857,0.3928095936133701,0.3928095936133701,-0.8039614683338043,0.49884576098804173,0.9990456262708737,-0.7152427522665485,0.428393191730484,1.1864283685836194,0.6027831121744145,0.6369761233848037,0.17410512476192191,1.0622595380909912,0.6709474376181863,0.2111917997668451,0.09914099907683403,0.2111917997668451,0.02309828334687722,-0.7152427522665485,0.0612563185418274,0.463737560425262,0.49884576098804173,0.1367560507410777,0.02309828334687722,-0.7152427522665485 2937 Cytoplasmic ribosomal proteins 31 75 3.082844469427277 0.0020503228209949 P61254,P60866,P62081,P62280,P23396,P39023,P46776,Q15418,P46783,P62917,P62277,P83881,P62750,P61353,P05387,P08865,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,P62829,Q9Y3U8,P62847,P35268,P46782,P46779,P62241 Processes and pathways WikiPathways msigdb_wp 136,504,505,506,384,387,389,292,155,650,649,289,423,542,562,680,682,454,82,83,325,225,95,604,607,243,372,367,599,738,743 2603,562,1638,1414,680,1530,682,874,1477,384,1245,325,1419,1644,1931,367,1311,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,1933,1855,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,1131,292,243 -1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.0612563185418274,0.5337207971688037,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,-0.2519914877556342,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,0.9990456262708737,1.0935808714347506 2937 Mapk family signaling cascades 47 87 3.077710908273942 0.0020859716937589 P46940,P49720,Q13177,P62140,P30086,P28066,Q9UL46,P06493,P31946,Q99460,O00231,Q99956,O43242,Q13813,P48556,Q92530,P49721,Q14997,Q96P70,Q9Y490,Q01082,P35998,Q9Y4G8,O00487,P17612,P55036,Q15008,P51665,O60725,P27361,P28072,P28074,P18206,P32121,P62191,P28070,Q06323,Q9UNM6,Q99436,Q13200,Q16181,P20618,Q9HCE1,P62993,P41240,P17980,Q14738 Processes and pathways Reactome Pathways msigdb_reactome 131,884,139,394,877,876,811,263,385,549,149,712,165,426,539,578,50,840,580,723,310,686,61,560,824,834,201,198,323,828,326,327,209,832,477,105,890,767,253,745,373,735,906,236,370,362,656 149,1106,560,1353,859,165,323,2255,919,2502,263,1529,824,362,209,735,2178,2877,1183,926,1184,1418,828,876,105,326,327,1247,2355,877,990,1060,385,832,2081,686,1310,1846,2755,370,1480,131,539,884,50,198,1649,834,1431,1254,1856,394,477,1374,1127,236,310,1071,2579,890,139,745,1605,1736,1380,426,2773,656,840,201,2092,373,2093,578,580,1344,253,549,712,906,1963,1397,811,767,1517,723,61 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,0.3928095936133701,1.3076973767692464,0.9350551147231273,-0.6279701240574134,0.35698364577547,-0.8941728675715074,1.0307485270519672,-0.015336908887356353,0.428393191730484,0.8702695242261951,1.155663166669387,0.49884576098804173,-0.5420991063561916,-1.9454153738987696,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.428393191730484,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.17410512476192191,-0.7152427522665485,0.3928095936133701,0.32091216739564127,0.28459191556669194,0.8375726207273704,0.428393191730484,-0.4575872142200032,0.5337207971688037,0.1367560507410777,-0.2519914877556342,-1.3694172456596465,0.8702695242261951,0.02309828334687722,1.5133178288044788,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,-0.09305436959858496,0.428393191730484,0.0612563185418274,0.17410512476192191,-0.2519914877556342,0.8375726207273704,0.7382358716884349,0.09914099907683403,0.24801958368154803,1.0935808714347506,0.9671485853633185,0.28459191556669194,-0.9859257988083908,0.3928095936133701,1.455398437788666,0.49884576098804173,-0.05405313922784484,-0.1719280959561597,0.09914099907683403,0.8046697182564764,-1.4193266439978673,0.5683656165997513,0.428393191730484,1.1864283685836194,-0.4575872142200032,0.8702695242261951,-0.4575872142200032,0.6369761233848037,0.6369761233848037,0.1367560507410777,1.0622595380909912,0.6709474376181863,0.5337207971688037,0.3928095936133701,-0.33327939055474815,0.09914099907683403,0.463737560425262,0.49884576098804173,0.02309828334687722,0.5337207971688037,2.1108177774831414 2937 Nonsense mediated decay nmd 41 86 3.064487851478045 0.0021804302977102 P46778,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P11940,P46783,P62917,P62277,P83881,Q04637,P62750,P61353,Q8ND04,Q92900,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P62861,Q9HAU5,P42766,P61927,P62829,Q9Y3U8,P62847,P62495,Q9BZI7,P46782,P35268,P62269,P46779,P62910,P62241 Processes and pathways Reactome Pathways msigdb_reactome 737,136,504,505,506,384,387,389,770,155,650,649,289,171,423,542,848,850,562,680,682,835,454,82,83,325,225,355,95,604,607,243,372,606,255,599,367,887,738,888,743 2603,562,1638,1414,680,770,1978,1530,682,874,1477,384,1245,325,1419,1644,990,1931,367,1311,1786,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,1933,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,606,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,1258,2761,2548,1600,289,1651,1691,1549,171,1131,2708,848,850,255,355,243,2166 -1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.0612563185418274,0.5337207971688037,0.463737560425262,-0.3743938386878874,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,0.32091216739564127,-0.33327939055474815,0.8702695242261951,0.1367560507410777,-0.21180894066884262,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.6027831121744145,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,0.17410512476192191,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,1.3076973767692464,0.24801958368154803,-1.222394988641525,0.428393191730484,0.428393191730484,1.0622595380909912,0.9027628846125711,1.0935808714347506,-0.4996758503153541 2937 Regulation of actin filament length 12 39 3.0606406783349542 0.0022086397690745 Q14019,P35611,P42345,P35241,P62993,Q9UQB8,P35080,P59998,Q01082,Q9NUQ9,Q9UJU6,Q13045 Processes and pathways GO Biological process msigdb_gobp 140,287,265,76,236,18,366,266,310,128,120,226 487,860,2395,1972,1114,1680,983,366,76,287,265,2226,1787,1196,1318,266,1319,931,236,310,1379,226,426,140,786,2447,1698,958,1505,1957,853,128,1100,1399,120,18,1470,2347,1105 0.704699791414857,0.3928095936133701,-0.759418488288081,-0.3743938386878874,0.24801958368154803,-0.13234464502495924,0.32091216739564127,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,0.1367560507410777,1.0307485270519672,0.1367560507410777,0.35698364577547,1.0935808714347506,0.9671485853633185,0.09914099907683403,1.1247147016520551,0.8046697182564764,1.455398437788666,0.463737560425262,-0.8039614683338043,-0.13234464502495924,0.35698364577547,0.02309828334687722,-0.33327939055474815,0.428393191730484,1.5420358124097335,0.28459191556669194,0.09914099907683403,1.5705949318057502,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.28459191556669194 2937 Regulation of anatomical structure size 27 84 3.0573549606363537 0.0022329967612559 O00443,P15311,Q14019,P42345,O96011,Q9UQB8,P59998,Q13813,P35611,P26038,Q86VI3,Q9HB40,Q01082,P50570,P08238,P78344,P35241,Q9UPN3,Q13045,P42892,Q9P265,P62993,P35080,O14786,Q9UJU6,Q9NUQ9,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 486,134,140,265,382,18,266,426,287,176,313,55,310,308,306,68,76,485,226,106,242,236,366,118,120,128,526 486,1108,118,487,860,2395,1921,2542,1972,1114,1680,382,2874,983,306,134,2077,563,176,777,366,76,287,265,106,1064,645,2226,1787,779,2311,1251,308,1125,1427,1196,2227,1429,1318,266,1319,931,2637,236,68,1937,310,1379,1735,226,1941,426,140,786,1897,1898,2447,2448,2042,1698,313,1014,958,2151,1748,1505,1957,1959,853,2829,55,526,128,242,668,1100,1399,120,2297,485,18,1470,2347,1105 0.704699791414857,0.24801958368154803,1.5705949318057502,0.704699791414857,0.3928095936133701,-0.759418488288081,-0.33327939055474815,-0.9398534966833773,-0.3743938386878874,0.24801958368154803,-0.13234464502495924,0.8375726207273704,-1.9454153738987696,0.32091216739564127,0.9671485853633185,1.484439279959394,-0.4575872142200032,0.6369761233848037,1.2776448956782354,0.463737560425262,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,1.6832758718136789,0.28459191556669194,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,0.463737560425262,-0.6714285051358926,0.17410512476192191,0.9671485853633185,0.24801958368154803,0.0612563185418274,0.2111917997668451,-0.5848621144923504,0.0612563185418274,0.1367560507410777,1.0307485270519672,0.1367560507410777,0.35698364577547,-1.0792715109109947,1.0935808714347506,2.0333215775625626,-0.33327939055474815,0.9671485853633185,0.09914099907683403,-0.1719280959561597,1.1247147016520551,-0.33327939055474815,0.8046697182564764,1.455398437788666,0.463737560425262,-0.29248013870191797,-0.29248013870191797,-0.8039614683338043,-0.8039614683338043,-0.4158281796670899,-0.13234464502495924,0.9671485853633185,0.32091216739564127,0.35698364577547,-0.4996758503153541,-0.1719280959561597,0.02309828334687722,-0.33327939055474815,-0.33327939055474815,0.428393191730484,-1.623692476299974,2.1871572148884817,0.704699791414857,1.5420358124097335,1.0935808714347506,0.5683656165997513,0.28459191556669194,0.09914099907683403,1.5705949318057502,-0.6279701240574134,0.7382358716884349,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.28459191556669194 2937 Regulation of actin filament organization 20 57 3.054422696932283 0.0022549411916488 Q13177,Q14019,P42345,P16949,Q9UQB8,P59998,Q13813,Q08722,P35611,P53367,Q01082,P35241,Q07157,Q13045,O75122,P62993,P35080,O14786,Q9UJU6,Q9NUQ9 Processes and pathways GO Biological process msigdb_gobp 139,140,265,143,18,266,426,424,287,51,310,76,479,226,471,236,366,118,120,128 118,487,860,2395,1972,471,1114,1680,983,2604,143,2026,366,76,287,265,2226,1787,1196,51,1318,266,2759,1254,1319,601,931,236,2511,310,479,424,1379,226,139,426,140,786,2093,2447,1698,958,755,1505,1957,853,1348,128,1963,1100,1399,120,18,1470,2347,1105,1577 1.5705949318057502,0.704699791414857,0.3928095936133701,-0.759418488288081,-0.3743938386878874,0.7382358716884349,0.24801958368154803,-0.13234464502495924,0.32091216739564127,-1.0323962561974658,1.4261935465788533,-0.4158281796670899,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,2.237423692928971,0.1367560507410777,1.0307485270519672,-1.3694172456596465,0.17410512476192191,0.1367560507410777,0.6027831121744145,0.35698364577547,1.0935808714347506,-0.8941728675715074,0.9671485853633185,0.7382358716884349,0.8046697182564764,0.09914099907683403,1.1247147016520551,1.455398437788666,0.8046697182564764,1.455398437788666,0.463737560425262,-0.4575872142200032,-0.8039614683338043,-0.13234464502495924,0.35698364577547,0.49884576098804173,0.02309828334687722,-0.33327939055474815,0.428393191730484,0.1367560507410777,1.5420358124097335,-0.33327939055474815,0.28459191556669194,0.09914099907683403,1.5705949318057502,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.28459191556669194,-0.015336908887356353 2937 Regulation of cellular component size 24 74 3.0520638161016698 0.0022727377652835 P15311,Q14019,P42345,O96011,Q9UQB8,P59998,Q13813,P35611,P26038,Q86VI3,Q01082,P50570,P08238,P78344,P35241,Q9UPN3,Q13045,Q9P265,P62993,P35080,O14786,Q9UJU6,Q9NUQ9,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 134,140,265,382,18,266,426,287,176,313,310,308,306,68,76,485,226,242,236,366,118,120,128,526 1108,118,487,860,2395,1921,1972,1114,1680,382,983,306,134,563,176,777,366,76,287,265,1064,645,2226,1787,1251,308,1125,1196,2227,1429,1318,266,1319,931,2637,236,68,1937,310,1379,226,1941,426,140,786,1897,1898,2447,2448,2042,1698,313,1014,958,2151,1748,1505,1957,1959,853,2829,526,128,242,668,1100,1399,120,2297,485,18,1470,2347,1105 0.24801958368154803,1.5705949318057502,0.704699791414857,0.3928095936133701,-0.759418488288081,-0.33327939055474815,-0.3743938386878874,0.24801958368154803,-0.13234464502495924,0.8375726207273704,0.32091216739564127,0.9671485853633185,1.484439279959394,0.6369761233848037,1.2776448956782354,0.463737560425262,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,0.28459191556669194,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,0.17410512476192191,0.9671485853633185,0.24801958368154803,0.2111917997668451,-0.5848621144923504,0.0612563185418274,0.1367560507410777,1.0307485270519672,0.1367560507410777,0.35698364577547,-1.0792715109109947,1.0935808714347506,2.0333215775625626,-0.33327939055474815,0.9671485853633185,0.09914099907683403,1.1247147016520551,-0.33327939055474815,0.8046697182564764,1.455398437788666,0.463737560425262,-0.29248013870191797,-0.29248013870191797,-0.8039614683338043,-0.8039614683338043,-0.4158281796670899,-0.13234464502495924,0.9671485853633185,0.32091216739564127,0.35698364577547,-0.4996758503153541,-0.1719280959561597,0.02309828334687722,-0.33327939055474815,-0.33327939055474815,0.428393191730484,-1.623692476299974,0.704699791414857,1.5420358124097335,1.0935808714347506,0.5683656165997513,0.28459191556669194,0.09914099907683403,1.5705949318057502,-0.6279701240574134,0.7382358716884349,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.28459191556669194 2937 Cellular component morphogenesis 31 117 3.0485022631045253 0.0022998518056762 P46940,P07900,Q9Y639,Q13177,Q9NR77,P16949,O60271,Q9UQB8,Q14444,O60749,P35613,P50570,P08238,Q9Y4G8,Q9UQ16,P78344,Q9UBN7,Q9UPN3,Q6SZW1,P18206,Q99829,Q13045,P33176,O00429,P42892,Q9P265,Q13614,Q04837,O14786,Q7Z406,Q9UJU6 Processes and pathways GO Biological process msigdb_gobp 131,245,408,139,13,143,261,18,428,282,420,308,306,61,194,68,80,485,87,209,482,226,473,345,106,242,110,115,118,119,120 915,345,2302,118,1767,1768,261,1770,282,1972,471,2599,2657,1114,1681,2261,245,306,1589,1306,143,640,209,1364,777,473,2130,420,106,1064,645,131,600,1251,308,1254,2230,2088,1067,931,68,1600,1733,1937,1071,2410,1895,115,889,2579,2090,2365,226,139,2318,1941,1005,110,786,1552,428,1202,2092,2093,1137,1898,2447,87,2046,1698,119,706,2519,1014,660,2586,2331,2916,1811,2796,959,1505,1213,1506,1959,1389,482,1457,1348,1153,2829,1755,906,526,13,1757,1397,242,80,120,2297,631,2594,1167,485,1231,194,18,1403,1470,2347,2115,557,1881,61,1295,408 0.35698364577547,0.9027628846125711,-0.6714285051358926,1.5705949318057502,-0.21180894066884262,-0.21180894066884262,1.0307485270519672,-0.21180894066884262,0.9990456262708737,-0.3743938386878874,0.7382358716884349,-1.0323962561974658,-1.1265583700744997,0.24801958368154803,-0.13234464502495924,-0.6279701240574134,1.0622595380909912,0.9671485853633185,-0.05405313922784484,0.1367560507410777,1.4261935465788533,0.5683656165997513,1.155663166669387,0.09914099907683403,0.463737560425262,0.7382358716884349,-0.4996758503153541,0.8046697182564764,1.6832758718136789,0.28459191556669194,0.5683656165997513,1.5133178288044788,0.6027831121744145,0.17410512476192191,0.9671485853633185,0.17410512476192191,-0.5848621144923504,-0.4575872142200032,0.28459191556669194,0.35698364577547,2.0333215775625626,-0.05405313922784484,-0.1719280959561597,-0.33327939055474815,0.28459191556669194,-0.759418488288081,-0.29248013870191797,1.627243250148423,0.3928095936133701,-0.9859257988083908,-0.4575872142200032,-0.7152427522665485,1.1247147016520551,1.455398437788666,-0.6714285051358926,-0.33327939055474815,0.32091216739564127,1.655335720828877,0.463737560425262,-0.015336908887356353,0.8046697182564764,0.2111917997668451,-0.4575872142200032,-0.4575872142200032,0.24801958368154803,-0.29248013870191797,-0.8039614683338043,1.8478045517497095,-0.4158281796670899,-0.13234464502495924,1.5705949318057502,0.5337207971688037,-0.8941728675715074,0.32091216739564127,0.5683656165997513,-0.9859257988083908,-0.6714285051358926,-2.589360161351481,-0.21180894066884262,-1.469700408349865,0.35698364577547,0.02309828334687722,0.2111917997668451,0.02309828334687722,-0.33327939055474815,0.09914099907683403,0.7382358716884349,0.0612563185418274,0.1367560507410777,0.24801958368154803,-1.623692476299974,-0.1719280959561597,0.3928095936133701,0.704699791414857,4.2518449635579465,-0.1719280959561597,0.09914099907683403,1.0935808714347506,1.901497527876068,1.5705949318057502,-0.6279701240574134,0.6027831121744145,-0.9859257988083908,0.24801958368154803,0.7382358716884349,0.2111917997668451,1.2170123744522818,3.7962488360202657,0.09914099907683403,0.0612563185418274,-0.6714285051358926,-0.4575872142200032,0.6709474376181863,-0.2519914877556342,2.1108177774831414,0.17410512476192191,0.8375726207273704 2937 Lipid binding 33 117 3.0353460361285296 0.0024025985700033 O14773,P46940,Q8WTV0,Q8NCC3,P37198,P07602,P35610,Q96SU4,P30536,O60749,Q9BQE5,P09429,P50897,P53367,O15118,Q01082,Q9Y4G8,Q00169,P56589,Q9UJY4,Q9UNH7,Q14108,P20073,P45880,Q13045,P04150,P21796,O00429,P28070,Q53T59,Q99623,O15173,P35080 Functions GO Molecular function msigdb_gomf 129,131,10,12,386,151,154,301,160,282,43,415,49,51,173,310,61,455,70,466,343,79,448,329,226,221,99,345,105,238,377,231,366 1039,915,1969,345,486,2497,129,173,231,1170,1581,1882,978,1883,2802,282,637,2068,1678,981,1473,221,2069,1413,151,983,2174,415,2681,823,1780,1178,733,448,2178,99,1059,2659,1183,105,2355,877,160,366,154,386,2357,329,645,131,540,49,1065,1316,1649,51,1934,2742,70,2759,2926,2511,455,837,310,1379,226,1941,545,1005,79,699,1863,941,1554,238,2046,2478,1743,753,12,2872,10,579,1387,755,1748,2650,301,1090,377,482,1665,853,43,2241,2456,1816,2243,1156,763,1462,1161,2734,806,466,909,1878,1289,1167,343,1290,722,723,61,2299,1105 0.28459191556669194,0.35698364577547,-0.3743938386878874,0.9027628846125711,0.704699791414857,-0.8941728675715074,1.5133178288044788,1.2776448956782354,1.0935808714347506,0.2111917997668451,-0.05405313922784484,-0.29248013870191797,0.32091216739564127,-0.29248013870191797,-1.5205468840168608,0.9990456262708737,0.5683656165997513,-0.4575872142200032,-0.13234464502495924,0.32091216739564127,0.02309828334687722,1.1247147016520551,-0.4575872142200032,0.0612563185418274,1.3968228224013606,0.32091216739564127,-0.5420991063561916,0.8046697182564764,-1.1742638113510904,0.428393191730484,-0.21180894066884262,0.2111917997668451,0.49884576098804173,0.7715583169098631,-0.5420991063561916,1.7110652769447776,0.28459191556669194,-1.1265583700744997,0.2111917997668451,1.6832758718136789,-0.7152427522665485,0.3928095936133701,1.33757659471794,0.8702695242261951,1.3672844525092513,0.8375726207273704,-0.7152427522665485,0.9350551147231273,0.5683656165997513,1.5133178288044788,0.6709474376181863,2.3364949483641926,0.28459191556669194,0.1367560507410777,-0.09305436959858496,2.237423692928971,-0.33327939055474815,-1.3199640839408484,1.9809980490909074,-1.3694172456596465,-3.311909712172878,-0.8941728675715074,0.7715583169098631,0.428393191730484,0.9671485853633185,0.09914099907683403,1.1247147016520551,-0.33327939055474815,0.6709474376181863,0.32091216739564127,1.901497527876068,0.5337207971688037,-0.2519914877556342,0.35698364577547,-0.015336908887356353,1.0935808714347506,-0.4158281796670899,-0.8488775839823314,-0.1719280959561597,0.49884576098804173,4.268556610395897,-1.8904581760074333,4.351275402719301,0.6369761233848037,0.09914099907683403,0.49884576098804173,-0.1719280959561597,-1.0792715109109947,0.9990456262708737,0.28459191556669194,0.8702695242261951,0.7382358716884349,-0.09305436959858496,0.428393191730484,2.5525992591256026,-0.5848621144923504,-0.8039614683338043,-0.21180894066884262,-0.5848621144923504,0.24801958368154803,0.49884576098804173,0.0612563185418274,0.24801958368154803,-1.2709592380232988,0.463737560425262,0.7715583169098631,0.3928095936133701,-0.2519914877556342,0.17410512476192191,0.24801958368154803,0.9350551147231273,0.17410512476192191,0.5337207971688037,0.5337207971688037,2.1108177774831414,-0.6279701240574134,0.28459191556669194 2937 Fc epsilon receptor fceri signaling 31 50 3.025630976308902 0.0024811491742289 P49720,Q13177,P45985,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P27361,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P62993,P19174,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,139,501,876,811,549,149,165,539,578,50,840,919,686,560,834,201,198,828,326,327,477,105,890,767,745,735,236,234,362,253 149,1106,560,1353,1919,165,919,2502,362,234,735,1183,926,1184,1418,828,876,105,326,327,1247,2355,686,1480,501,539,884,50,198,834,1431,1856,477,1374,1127,236,1259,2444,890,139,745,1006,840,201,2093,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,-0.8941728675715074,0.8702695242261951,1.0935808714347506,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.428393191730484,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.17410512476192191,-0.7152427522665485,0.5337207971688037,0.02309828334687722,0.704699791414857,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,1.0935808714347506,0.17410512476192191,-0.8039614683338043,0.3928095936133701,1.455398437788666,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,-0.4575872142200032,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Regulation of actin cytoskeleton 17 46 3.0101577594997107 0.0026111202821079 O15144,O60610,P46940,P15311,Q13177,P62140,P35241,P41240,P26038,Q9UQB8,P35580,Q7Z406,Q86VI3,P59998,P18206,P35080,P35579 Processes and pathways KEGG Pathways msigdb_kegg 487,488,131,134,139,394,76,370,176,18,113,119,313,266,209,366,63 487,860,726,488,1412,2502,2261,983,1529,870,134,209,1364,1182,176,828,1247,366,76,63,113,1846,2755,370,2084,131,266,1254,931,2637,394,1071,139,545,1942,2093,1698,119,313,660,958,1505,1623,18,1470,2347 0.704699791414857,0.3928095936133701,0.49884576098804173,0.704699791414857,0.0612563185418274,-0.8941728675715074,-0.6279701240574134,0.32091216739564127,-0.015336908887356353,0.3928095936133701,1.484439279959394,1.155663166669387,0.09914099907683403,0.2111917997668451,1.2776448956782354,0.428393191730484,0.17410512476192191,0.8702695242261951,1.9281348523770536,2.085115891068643,1.627243250148423,-0.2519914877556342,-1.3694172456596465,0.8702695242261951,-0.4575872142200032,1.5133178288044788,1.0307485270519672,0.17410512476192191,0.35698364577547,-1.0792715109109947,0.8375726207273704,0.28459191556669194,1.455398437788666,0.6709474376181863,-0.33327939055474815,-0.4575872142200032,-0.13234464502495924,1.5705949318057502,0.9671485853633185,0.5683656165997513,0.35698364577547,0.02309828334687722,-0.05405313922784484,3.7962488360202657,0.0612563185418274,-0.6714285051358926 2937 Microtubules 20 45 3.0097190039080064 0.002614894852982 O60830,P27816,Q13564,P61163,P55209,Q02818,Q6P158,Q13813,Q8NEM2,Q9NZZ3,Q13409,P04350,Q9HC35,P42025,Q14203,Q96CM8,O43663,Q13885,O75347,O43813 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 9,497,654,393,392,29,703,426,708,718,311,305,341,689,211,756,589,747,728,112 1106,589,112,9,728,305,1057,986,497,2179,736,1983,2223,689,2227,392,1254,393,29,1549,311,654,1861,426,747,211,2139,1608,1999,703,1805,1496,1807,708,2099,1706,756,1568,1153,341,1623,1163,718,972,1290 0.24801958368154803,0.6027831121744145,1.627243250148423,4.351275402719301,0.49884576098804173,0.9671485853633185,0.28459191556669194,0.32091216739564127,0.704699791414857,-0.5420991063561916,0.49884576098804173,-0.3743938386878874,-0.5848621144923504,0.5337207971688037,-0.5848621144923504,0.8375726207273704,0.17410512476192191,0.8375726207273704,3.0450375649426276,-0.015336908887356353,0.9671485853633185,0.5683656165997513,-0.2519914877556342,0.8046697182564764,0.49884576098804173,1.155663166669387,-0.4996758503153541,-0.05405313922784484,-0.3743938386878874,0.5337207971688037,-0.21180894066884262,0.02309828334687722,-0.21180894066884262,0.5337207971688037,-0.4575872142200032,-0.13234464502495924,0.49884576098804173,-0.015336908887356353,0.24801958368154803,0.9350551147231273,-0.05405313922784484,0.24801958368154803,0.5337207971688037,0.35698364577547,0.17410512476192191 2937 Endosome 50 174 3.004559693828272 0.0026596556271836 O15144,O14773,Q7Z3U7,P15311,Q9UIQ6,P62820,Q5VW38,P42858,Q5VYK3,Q8IUR0,O95342,P07602,P20645,Q96SU4,P09496,O60749,O14828,P09429,O60826,Q96QK1,O15118,P35613,P50570,Q9Y4G8,P30533,O43237,P20339,P62826,Q9UJY4,Q9H4M9,Q9UNH7,Q9UBN7,Q14108,Q6Y7W6,O15127,Q92544,Q9BTU6,O75165,O14617,O15498,P42892,Q14C86,Q13614,P62993,P04439,O14786,Q9UJU6,Q13546,Q00610,Q13510 Localization GO Cellular component msigdb_gocc 487,129,137,134,277,395,15,144,270,548,22,151,25,301,535,282,281,415,175,581,173,420,308,61,183,182,563,565,466,340,343,80,79,617,320,91,354,220,469,346,106,512,110,236,232,118,120,510,508,397 2120,469,129,118,281,173,320,487,1406,346,182,1471,978,2802,1634,282,175,2021,220,2814,1773,2657,2024,1678,22,920,1411,1054,732,1473,232,2261,1413,151,2174,415,535,1415,1306,2681,823,2633,1178,1887,771,2604,134,2825,1362,563,25,924,775,828,1119,1247,2307,2741,183,878,832,2081,420,1846,2082,1932,882,144,106,308,1597,2085,1598,1125,1728,1599,2230,2088,1542,1989,931,395,565,236,1546,508,1071,1941,397,510,1005,110,2270,79,1329,1606,699,512,1554,2092,1203,2093,1866,15,270,2867,842,617,2478,137,548,1745,753,2004,661,2764,1612,91,1088,1707,2891,1614,1748,2855,581,301,1090,1024,1347,1665,2380,354,2009,1667,1618,1816,1819,1218,1030,762,763,340,1283,2246,1226,1227,2734,718,1285,805,806,807,80,719,2206,857,277,120,466,1878,2297,631,2594,1289,1575,1167,343,2208,1290,1517,1719,61,1294,2299 -0.4996758503153541,0.7382358716884349,1.5133178288044788,1.5705949318057502,0.9990456262708737,1.2776448956782354,0.9350551147231273,0.704699791414857,0.0612563185418274,0.9027628846125711,1.2474172170623723,0.02309828334687722,0.32091216739564127,-1.5205468840168608,-0.09305436959858496,0.9990456262708737,1.2776448956782354,-0.4158281796670899,1.1247147016520551,-1.5718746398609995,-0.21180894066884262,-1.1265583700744997,-0.4158281796670899,-0.13234464502495924,3.513047173839545,0.35698364577547,0.0612563185418274,0.28459191556669194,0.49884576098804173,0.02309828334687722,1.0935808714347506,-0.6279701240574134,0.0612563185418274,1.3968228224013606,-0.5420991063561916,0.8046697182564764,0.6709474376181863,0.0612563185418274,0.1367560507410777,-1.1742638113510904,0.428393191730484,-1.0792715109109947,0.2111917997668451,-0.29248013870191797,0.463737560425262,-1.0323962561974658,1.484439279959394,-1.623692476299974,0.09914099907683403,0.6369761233848037,3.2128208825072786,0.35698364577547,0.463737560425262,0.428393191730484,0.24801958368154803,0.17410512476192191,-0.6714285051358926,-1.3199640839408484,1.2474172170623723,0.3928095936133701,0.428393191730484,-0.4575872142200032,0.8046697182564764,-0.2519914877556342,-0.4575872142200032,-0.33327939055474815,0.3928095936133701,1.4261935465788533,1.6832758718136789,0.9671485853633185,-0.05405313922784484,-0.4575872142200032,-0.05405313922784484,0.24801958368154803,-0.1719280959561597,-0.05405313922784484,-0.5848621144923504,-0.4575872142200032,-0.015336908887356353,-0.3743938386878874,0.35698364577547,0.8375726207273704,0.6369761233848037,1.0935808714347506,-0.015336908887356353,0.704699791414857,0.28459191556669194,-0.33327939055474815,0.8375726207273704,0.704699791414857,0.32091216739564127,1.655335720828877,-0.6279701240574134,1.901497527876068,0.1367560507410777,-0.05405313922784484,0.5337207971688037,0.704699791414857,-0.015336908887356353,-0.4575872142200032,0.2111917997668451,-0.4575872142200032,-0.2519914877556342,3.994138285325319,1.0307485270519672,-1.8360492193607452,0.428393191730484,0.6027831121744145,-0.8488775839823314,1.484439279959394,0.6709474376181863,-0.1719280959561597,0.49884576098804173,-0.3743938386878874,0.5683656165997513,-1.3694172456596465,-0.05405313922784484,1.8207460887469624,0.28459191556669194,-0.13234464502495924,-2.0570175153164287,-0.05405313922784484,-0.1719280959561597,-1.7288348009106087,0.6369761233848037,0.9990456262708737,0.28459191556669194,0.32091216739564127,0.1367560507410777,-0.09305436959858496,-0.7152427522665485,0.9027628846125711,-0.3743938386878874,-0.09305436959858496,-0.05405313922784484,-0.21180894066884262,-0.21180894066884262,0.2111917997668451,0.32091216739564127,0.49884576098804173,0.49884576098804173,0.9350551147231273,0.17410512476192191,-0.5848621144923504,0.2111917997668451,0.2111917997668451,-1.2709592380232988,0.5337207971688037,0.17410512476192191,0.463737560425262,0.463737560425262,0.463737560425262,1.901497527876068,0.5337207971688037,-0.5420991063561916,0.428393191730484,1.0307485270519672,1.5705949318057502,0.7715583169098631,-0.2519914877556342,-0.6279701240574134,0.6027831121744145,-0.9859257988083908,0.17410512476192191,-0.015336908887356353,0.24801958368154803,0.9350551147231273,-0.5420991063561916,0.17410512476192191,0.02309828334687722,-0.13234464502495924,2.1108177774831414,0.17410512476192191,-0.6279701240574134 2937 Dendrite morphogenesis 6 28 2.998178312385254 0.0027159871433792 Q9UBN7,Q9UQB8,O14786,Q6SZW1,Q9UJU6,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 80,18,118,87,120,61 118,1770,1681,2261,1364,1064,1251,1254,1067,1937,889,1941,428,2092,2447,87,1213,1755,1757,1397,80,120,2297,631,194,18,1881,61 1.5705949318057502,-0.21180894066884262,-0.13234464502495924,-0.6279701240574134,0.09914099907683403,0.28459191556669194,0.17410512476192191,0.17410512476192191,0.28459191556669194,-0.33327939055474815,0.3928095936133701,-0.33327939055474815,0.8046697182564764,-0.4575872142200032,-0.8039614683338043,1.8478045517497095,0.2111917997668451,-0.1719280959561597,-0.1719280959561597,0.09914099907683403,1.901497527876068,1.5705949318057502,-0.6279701240574134,0.6027831121744145,1.2170123744522818,3.7962488360202657,-0.2519914877556342,2.1108177774831414 2937 Intrinsic component of plasma membrane 19 60 2.991088555895686 0.0027798486580514 Q9Y639,O95864,Q8WTV0,Q9UIQ6,P20645,P53985,Q08722,O60637,P35613,O15118,Q9Y4G8,Q86UP2,P78310,Q9BTU6,O15498,O43657,P04439,O43813,O14786 Localization GO Cellular component msigdb_gocc 408,490,10,277,25,161,424,174,420,173,61,229,478,354,346,101,232,112,118 1039,915,118,1919,173,346,101,112,174,490,533,1054,732,232,2069,2305,2261,1415,2353,2633,1178,2125,1243,2077,25,2128,1928,2081,420,1685,1124,1125,161,1987,1429,478,1795,2137,1895,424,892,1003,2092,1334,1273,229,2003,10,1612,1709,1024,1564,354,1160,1963,277,1965,2208,61,408 0.28459191556669194,0.35698364577547,1.5705949318057502,-0.33327939055474815,1.2776448956782354,0.9027628846125711,1.6832758718136789,1.627243250148423,1.2776448956782354,0.704699791414857,0.6709474376181863,0.28459191556669194,0.49884576098804173,1.0935808714347506,-0.4575872142200032,-0.6714285051358926,-0.6279701240574134,0.0612563185418274,-0.7152427522665485,-1.0792715109109947,0.2111917997668451,-0.4996758503153541,0.17410512476192191,-0.4575872142200032,3.2128208825072786,-0.4996758503153541,-0.33327939055474815,-0.4575872142200032,0.8046697182564764,-0.13234464502495924,0.24801958368154803,0.24801958368154803,1.33757659471794,-0.3743938386878874,0.0612563185418274,0.7382358716884349,-0.21180894066884262,-0.4996758503153541,-0.29248013870191797,0.8046697182564764,0.3928095936133701,0.32091216739564127,-0.4575872142200032,0.1367560507410777,0.17410512476192191,1.1247147016520551,-0.3743938386878874,4.351275402719301,-0.05405313922784484,-0.13234464502495924,0.32091216739564127,-0.015336908887356353,0.9027628846125711,0.24801958368154803,-0.33327939055474815,1.0307485270519672,-0.33327939055474815,-0.5420991063561916,2.1108177774831414,0.8375726207273704 2937 Actin polymerization or depolymerization 14 44 2.966626091053249 0.0030108687419345 O15144,Q13813,Q14019,P35611,P42345,P35241,P62993,Q9UQB8,P35080,P59998,Q01082,Q9NUQ9,Q9UJU6,Q13045 Processes and pathways GO Biological process msigdb_gobp 487,426,140,287,265,76,236,18,366,266,310,128,120,226 487,860,2395,488,1972,1114,1680,983,1364,366,76,287,265,2226,1787,1196,2086,1318,266,1319,931,236,310,1379,226,426,140,786,2447,1698,660,958,1505,1957,853,1623,128,1100,1399,120,18,1470,2347,1105 0.704699791414857,0.3928095936133701,-0.759418488288081,0.704699791414857,-0.3743938386878874,0.24801958368154803,-0.13234464502495924,0.32091216739564127,0.09914099907683403,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,-0.4575872142200032,0.1367560507410777,1.0307485270519672,0.1367560507410777,0.35698364577547,1.0935808714347506,0.9671485853633185,0.09914099907683403,1.1247147016520551,0.8046697182564764,1.455398437788666,0.463737560425262,-0.8039614683338043,-0.13234464502495924,0.5683656165997513,0.35698364577547,0.02309828334687722,-0.33327939055474815,0.428393191730484,-0.05405313922784484,1.5420358124097335,0.28459191556669194,0.09914099907683403,1.5705949318057502,3.7962488360202657,0.0612563185418274,-0.6714285051358926,0.28459191556669194 2937 Pcp ce pathway 30 50 2.964698010209623 0.0030298018958581 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P09496,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,535,539,578,50,840,919,686,926,560,834,201,198,326,327,477,832,105,890,767,745,735,362,253,508 149,1106,560,1353,165,919,1678,1411,2791,983,535,1837,362,735,1183,926,1184,1418,876,105,326,327,832,686,1480,539,884,50,198,1599,834,1431,1856,931,477,1374,1127,1546,508,890,745,2581,840,201,578,1748,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,-0.13234464502495924,0.0612563185418274,-1.469700408349865,0.32091216739564127,0.6709474376181863,-0.2519914877556342,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,-0.05405313922784484,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.35698364577547,0.7382358716884349,0.09914099907683403,0.24801958368154803,-0.015336908887356353,0.704699791414857,0.3928095936133701,0.49884576098804173,-0.9859257988083908,0.428393191730484,1.1864283685836194,0.6369761233848037,-0.1719280959561597,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Macrocytic anemia 16 35 2.962045308328336 0.0030560281010967 Q99707,O00429,Q9P2J5,Q6P4A7,P00374,P61254,Q9Y3A5,P62847,P61353,P60866,P62081,P39019,P62899,P46783,P61011,P42766 Drugs and Diseases Human Phenotype Ontology msigdb_hp 302,345,668,704,103,136,632,372,542,504,505,82,83,155,476,95 345,1354,1883,1835,103,1681,1414,1781,985,682,924,82,95,1189,155,504,476,136,1650,542,505,1489,1936,1689,372,2847,83,1545,1131,704,1658,302,668,632,2061 0.9027628846125711,0.09914099907683403,-0.29248013870191797,-0.2519914877556342,1.6832758718136789,-0.13234464502495924,0.0612563185418274,-0.21180894066884262,0.32091216739564127,0.5337207971688037,0.35698364577547,1.8747212260962505,1.7387054861501252,0.2111917997668451,1.3672844525092513,0.704699791414857,0.7382358716884349,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.704699791414857,0.02309828334687722,-0.33327939055474815,-0.13234464502495924,0.8702695242261951,-1.7288348009106087,1.8747212260962505,-0.015336908887356353,0.24801958368154803,0.5337207971688037,-0.09305436959858496,0.9990456262708737,0.5683656165997513,0.6027831121744145,-0.4158281796670899 2937 Neuron development 43 168 2.961283105908312 0.0030636018907819 P46940,P07900,Q9Y639,Q13177,Q9NR77,Q9NZQ3,P16949,O14949,O60271,Q9UQB8,Q9Y6M7,Q14444,Q9BTW9,P30536,Q99707,P08670,P09429,P50897,P35613,Q9H4A3,P50570,P08238,Q9Y4G8,Q9UQ16,P78344,Q9H4M9,Q9UBN7,Q14108,Q9UPN3,Q6SZW1,P18206,Q99829,P33176,Q15555,P42892,P00374,Q9P265,Q13614,Q02790,O14786,Q9UJU6,Q9NQC3,P63104 Processes and pathways GO Biological process msigdb_gobp 131,245,408,139,13,142,143,381,261,18,148,428,163,160,302,414,415,49,420,57,308,306,61,194,68,340,80,79,485,87,209,482,473,348,106,103,242,110,509,118,120,526,507 1764,915,2302,1108,118,381,1767,1831,1354,2395,2863,261,1921,2802,1770,2020,864,1677,2599,2657,1114,1526,1303,2260,1412,103,1681,981,2874,2261,245,306,414,415,1589,143,825,209,2026,1364,497,160,777,473,1121,2130,420,2682,1312,106,1064,2084,645,131,1251,308,49,1598,1852,1253,2742,1254,2230,2088,1067,931,2664,507,68,1600,1733,1937,1990,1071,509,2410,1895,889,2579,566,1379,1199,2365,139,1003,2318,1941,1605,110,696,79,2581,938,786,428,1897,1554,2092,1333,348,2512,2093,1898,2447,1268,842,87,2046,1698,1142,706,1014,660,2692,2330,2916,1811,2149,2485,959,1505,1213,1506,1959,1389,302,482,800,1457,163,1569,1153,1617,2829,1755,57,340,906,526,13,1757,2733,1397,2734,142,2735,242,908,807,80,120,1761,2297,631,485,1231,194,18,1403,1716,2347,2115,975,1881,61,1295,408,148 -0.21180894066884262,0.35698364577547,-0.6714285051358926,0.24801958368154803,1.5705949318057502,0.8375726207273704,-0.21180894066884262,-0.2519914877556342,0.09914099907683403,-0.759418488288081,-1.8360492193607452,1.0307485270519672,-0.33327939055474815,-1.5205468840168608,-0.21180894066884262,-0.4158281796670899,0.3928095936133701,-0.13234464502495924,-1.0323962561974658,-1.1265583700744997,0.24801958368154803,-0.015336908887356353,0.1367560507410777,-0.6279701240574134,0.0612563185418274,1.6832758718136789,-0.13234464502495924,0.32091216739564127,-1.9454153738987696,-0.6279701240574134,1.0622595380909912,0.9671485853633185,0.8046697182564764,0.8046697182564764,-0.05405313922784484,1.4261935465788533,0.428393191730484,1.155663166669387,-0.4158281796670899,0.09914099907683403,0.704699791414857,1.33757659471794,0.463737560425262,0.7382358716884349,0.24801958368154803,-0.4996758503153541,0.8046697182564764,-1.1742638113510904,0.1367560507410777,1.6832758718136789,0.28459191556669194,-0.4575872142200032,0.5683656165997513,1.5133178288044788,0.17410512476192191,0.9671485853633185,2.3364949483641926,-0.05405313922784484,-0.2519914877556342,0.17410512476192191,-1.3199640839408484,0.17410512476192191,-0.5848621144923504,-0.4575872142200032,0.28459191556669194,0.35698364577547,-1.1265583700744997,0.704699791414857,2.0333215775625626,-0.05405313922784484,-0.1719280959561597,-0.33327939055474815,-0.3743938386878874,0.28459191556669194,0.704699791414857,-0.759418488288081,-0.29248013870191797,0.3928095936133701,-0.9859257988083908,0.6369761233848037,0.09914099907683403,0.2111917997668451,-0.7152427522665485,1.455398437788666,0.32091216739564127,-0.6714285051358926,-0.33327939055474815,-0.05405313922784484,1.655335720828877,0.5337207971688037,1.901497527876068,-0.9859257988083908,0.35698364577547,0.463737560425262,0.8046697182564764,-0.29248013870191797,-0.015336908887356353,-0.4575872142200032,0.1367560507410777,0.9027628846125711,-0.8941728675715074,-0.4575872142200032,-0.29248013870191797,-0.8039614683338043,0.17410512476192191,0.428393191730484,1.8478045517497095,-0.4158281796670899,-0.13234464502495924,0.24801958368154803,0.5337207971688037,0.32091216739564127,0.5683656165997513,-1.1742638113510904,-0.6714285051358926,-2.589360161351481,-0.21180894066884262,-0.4996758503153541,-0.8488775839823314,0.35698364577547,0.02309828334687722,0.2111917997668451,0.02309828334687722,-0.33327939055474815,0.09914099907683403,0.9990456262708737,0.7382358716884349,0.463737560425262,0.0612563185418274,1.33757659471794,-0.015336908887356353,0.24801958368154803,-0.05405313922784484,-1.623692476299974,-0.1719280959561597,2.161837222901003,0.9350551147231273,0.3928095936133701,0.704699791414857,4.2518449635579465,-0.1719280959561597,-1.2709592380232988,0.09914099907683403,-1.2709592380232988,1.455398437788666,-1.2709592380232988,1.0935808714347506,0.3928095936133701,0.463737560425262,1.901497527876068,1.5705949318057502,-0.1719280959561597,-0.6279701240574134,0.6027831121744145,0.7382358716884349,0.2111917997668451,1.2170123744522818,3.7962488360202657,0.09914099907683403,-0.13234464502495924,-0.6714285051358926,-0.4575872142200032,0.35698364577547,-0.2519914877556342,2.1108177774831414,0.17410512476192191,0.8375726207273704,1.4261935465788533 2937 Microtubule 32 106 2.958023617068901 0.0030961840128975 P46940,Q9BSJ2,Q9Y6G9,P16949,Q9UQB8,P06493,Q9H6D7,Q9BTW9,Q14152,Q13409,P50570,P04350,O43237,Q9UQ16,Q9HC35,Q14204,Q9UBN7,P50402,Q14203,Q9UPN3,Q6SZW1,Q9H0B6,P33176,O75122,O00429,Q15555,Q9Y496,Q96CW5,Q92974,Q02790,Q9Y266,Q00610 Localization GO Cellular component msigdb_gocc 131,403,280,143,18,263,164,163,180,311,308,305,182,194,341,332,80,330,211,485,87,92,473,471,345,348,259,376,519,509,121,508 1968,345,1767,816,182,2018,589,863,1883,471,728,592,1302,1115,305,263,1057,771,143,734,1182,497,1309,473,2682,1846,1367,1313,1064,645,131,1250,1191,330,308,1426,1252,648,1484,2826,2511,1260,1937,508,1796,2607,509,1074,2412,1604,311,895,1380,747,697,180,211,332,2794,1863,940,2184,348,1010,1267,2851,1898,1494,87,1807,2275,2764,1706,1453,519,376,1616,2283,1152,1022,2106,1456,403,163,1568,1153,1667,92,164,341,1757,2387,718,805,80,1400,1516,2887,485,194,18,121,259,1520,1763,280 -0.3743938386878874,0.9027628846125711,-0.21180894066884262,0.428393191730484,1.2474172170623723,-0.4158281796670899,0.6027831121744145,0.3928095936133701,-0.29248013870191797,0.7382358716884349,0.49884576098804173,0.6027831121744145,0.1367560507410777,0.24801958368154803,0.9671485853633185,1.0307485270519672,0.28459191556669194,0.463737560425262,1.4261935465788533,0.49884576098804173,0.2111917997668451,0.704699791414857,0.1367560507410777,0.7382358716884349,-1.1742638113510904,-0.2519914877556342,0.09914099907683403,0.1367560507410777,0.28459191556669194,0.5683656165997513,1.5133178288044788,0.17410512476192191,0.2111917997668451,0.9350551147231273,0.9671485853633185,0.0612563185418274,0.17410512476192191,0.5683656165997513,0.02309828334687722,-1.623692476299974,-0.8941728675715074,0.17410512476192191,-0.33327939055474815,0.704699791414857,-0.21180894066884262,-1.0323962561974658,0.704699791414857,0.28459191556669194,-0.759418488288081,-0.05405313922784484,0.9671485853633185,0.3928095936133701,0.09914099907683403,0.49884576098804173,0.5337207971688037,1.2776448956782354,1.155663166669387,0.9350551147231273,-1.469700408349865,-0.2519914877556342,0.35698364577547,-0.5420991063561916,0.9027628846125711,0.32091216739564127,0.17410512476192191,-1.7288348009106087,-0.29248013870191797,0.02309828334687722,1.8478045517497095,-0.21180894066884262,-0.6279701240574134,-1.3694172456596465,-0.13234464502495924,0.0612563185418274,0.704699791414857,0.8702695242261951,-0.05405313922784484,-0.6279701240574134,0.24801958368154803,0.32091216739564127,-0.4575872142200032,0.0612563185418274,0.8375726207273704,1.33757659471794,-0.015336908887356353,0.24801958368154803,-0.09305436959858496,1.8207460887469624,1.33757659471794,0.9350551147231273,-0.1719280959561597,-0.7152427522665485,0.5337207971688037,0.463737560425262,1.901497527876068,0.09914099907683403,0.02309828334687722,-2.0009314909515403,0.7382358716884349,1.2170123744522818,3.7962488360202657,1.5705949318057502,1.0622595380909912,0.02309828334687722,-0.1719280959561597,1.0307485270519672 2937 Supramolecular fiber organization 44 163 2.943251549658024 0.0032478439832854 O15144,Q9BSJ2,P15311,Q13177,Q14019,P42345,P16949,Q9UQB8,P23396,P59998,Q96JJ3,Q9BTW9,Q9Y5K6,P07197,Q13813,Q08722,P35611,P08670,P53367,Q01082,Q9H2G2,Q05682,P08238,P04350,Q15942,P61758,P35241,Q14204,Q9UBN7,Q13546,Q14203,Q9UHV9,Q07157,Q13045,O75122,Q96CW5,P62993,Q92974,P35080,O14786,Q02790,Q9UJU6,Q9NUQ9,Q68EM7 Processes and pathways GO Biological process msigdb_gobp 487,403,134,139,140,265,143,18,384,266,434,163,440,157,426,424,287,414,51,310,189,59,306,305,203,453,76,332,80,510,211,484,479,226,471,376,236,519,366,118,509,120,128,251 1968,725,1041,1969,118,487,860,816,2395,863,978,2542,488,1972,471,2463,1114,2024,1680,1836,305,2261,2070,157,983,306,414,822,1306,823,870,1640,2806,2604,1842,134,1179,143,2026,2178,384,1364,1182,1309,1643,366,1121,76,287,1310,2682,265,1064,645,2226,1787,1849,1537,1852,1427,1196,51,2086,742,1318,266,2759,1254,1319,601,2360,1067,931,453,1257,236,2511,2136,1733,310,509,59,479,2412,424,1379,2090,1735,226,139,2318,568,510,545,1380,426,697,140,938,211,332,786,1552,1897,1693,1863,2184,1202,897,1010,203,2093,1137,2447,2040,251,950,1698,660,1699,2619,1706,958,519,959,755,1454,376,1505,1957,434,580,1344,799,1346,2106,853,1348,403,163,189,1623,128,1963,80,1100,1399,720,484,2932,1516,120,2594,2887,1672,18,1470,1232,2347,1294,440,1105,1577 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2937 Eukaryotic translation elongation 36 78 2.9348754249349835 0.0033368162336522 P46778,P61254,P26641,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P62861,P13639,P42766,P61927,P62829,Q9Y3U8,P62847,P35268,P62269,P46782,P62910,P46779,P62241 Processes and pathways Reactome Pathways msigdb_reactome 737,136,642,504,505,506,384,387,389,155,650,649,289,423,542,562,680,682,835,454,82,83,325,225,872,95,604,607,243,372,367,887,599,888,738,743 2603,562,1638,1414,680,872,1530,682,874,1477,384,989,1245,325,642,1419,1185,1644,1931,367,1311,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,1933,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,1073,1131,243 -1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.0612563185418274,0.5337207971688037,0.3928095936133701,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,0.32091216739564127,0.17410512476192191,0.9350551147231273,0.5683656165997513,0.0612563185418274,0.2111917997668451,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.28459191556669194,0.24801958368154803,1.0935808714347506 2937 Regulation of actin cytoskeleton 10 30 2.9310473813394653 0.0033782125183037 O00443,P46940,P15311,Q13177,P35241,P41240,P26038,Q9UQB8,P35580,P18206 Processes and pathways WikiPathways msigdb_wp 486,131,134,139,76,370,176,18,113,209 486,488,1412,2502,983,870,134,209,1364,1182,176,828,1247,76,113,1846,370,131,1254,931,1071,139,1942,2093,660,1505,1623,18,1470,2347 0.704699791414857,0.704699791414857,0.0612563185418274,-0.8941728675715074,0.32091216739564127,0.3928095936133701,1.484439279959394,1.155663166669387,0.09914099907683403,0.2111917997668451,1.2776448956782354,0.428393191730484,0.17410512476192191,1.9281348523770536,1.627243250148423,-0.2519914877556342,0.8702695242261951,1.5133178288044788,0.17410512476192191,0.35698364577547,0.28459191556669194,1.455398437788666,-0.33327939055474815,-0.4575872142200032,0.5683656165997513,0.02309828334687722,-0.05405313922784484,3.7962488360202657,0.0612563185418274,-0.6714285051358926 2937 Ribosome 30 73 2.922280836080665 0.0034747807237409 P61254,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,P05387,P08865,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,P62829,Q9Y3U8,P62847,P35268,P46782,P46779,P62241 Processes and pathways KEGG Pathways msigdb_kegg 136,504,505,506,384,387,389,155,650,649,289,423,542,562,680,682,454,82,83,325,225,95,604,607,243,372,367,599,738,743 2603,562,1638,1414,680,1530,682,874,1477,384,1245,325,1419,1644,1931,367,1311,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,1933,504,1197,136,1650,542,1432,604,505,743,1489,1857,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,1131,2288,243 -1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.0612563185418274,0.5337207971688037,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,-0.6279701240574134,1.0935808714347506 2937 Recycling pathway of l1 8 21 2.9189505770663486 0.0035121190172748 Q9UQ16,P50570,P15311,P35241,P26038,Q15418,P04350,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 194,308,134,76,176,292,305,508 1678,1302,1411,305,535,134,176,1247,76,308,1855,1599,1546,508,747,292,1898,1748,1568,1153,194 -0.13234464502495924,0.1367560507410777,0.0612563185418274,0.9671485853633185,0.6709474376181863,1.484439279959394,1.2776448956782354,0.17410512476192191,1.9281348523770536,0.9671485853633185,-0.2519914877556342,-0.05405313922784484,-0.015336908887356353,0.704699791414857,0.49884576098804173,0.9990456262708737,-0.29248013870191797,-0.1719280959561597,-0.015336908887356353,0.24801958368154803,1.2170123744522818 2937 Adaptive immune system 86 172 2.918735672450734 0.0035145409850736 Q99460,P09496,P48556,Q92530,P49721,Q15370,O00487,Q15819,Q9H0B6,P28070,Q14738,Q16763,Q8N8S7,P55786,Q13177,Q14139,O00231,P52732,O43242,Q9UII4,Q15436,P35998,O43237,Q9UQ16,Q15008,P51665,P42025,Q14203,Q7Z6Z7,Q9BXS5,Q9UNM6,Q13885,Q13200,P20618,P62993,P19174,P04439,O95376,Q9Y496,Q99436,Q9UIQ6,Q9Y6G9,P42345,Q9UJX3,Q9UL46,O94979,O75935,Q14997,Q13409,P50570,Q93034,P04350,Q9NZ32,Q92990,P17612,P55036,Q14204,O95714,P28072,P28074,P30260,Q13561,Q06323,P41240,Q9ULT8,P17980,P49720,P61163,P31751,P28066,P31946,Q13867,Q13617,O94822,Q9Y3I1,P09429,Q5T4S7,O75832,P22314,P61086,P62191,P78310,P33176,Q9UJW0,Q00610,P63104 Processes and pathways Reactome Pathways msigdb_reactome 549,535,539,578,50,572,560,611,92,105,656,126,660,135,139,655,149,648,165,721,701,686,182,194,201,198,689,211,752,760,767,747,745,735,236,234,232,731,259,253,277,280,265,810,811,284,283,840,311,308,851,305,855,335,824,834,332,820,326,327,829,895,890,370,910,362,884,393,878,876,385,427,425,413,975,415,944,919,924,452,477,478,473,528,508,507 1764,1968,2907,149,1106,560,1353,1919,182,165,1471,1924,919,283,413,1586,1678,284,1302,1359,731,1303,820,1411,2502,1054,305,232,2261,2791,415,535,1415,2073,824,362,234,735,924,1183,926,1184,1418,2546,2128,876,105,326,327,2028,2741,990,1060,829,878,385,473,686,370,689,265,1480,2226,1787,539,884,50,308,2085,1124,198,648,1986,1196,997,1599,1729,834,2228,135,2882,1431,1254,1935,452,393,1856,1730,477,1374,1127,1257,236,1546,507,2511,1259,1068,478,508,2607,2444,2579,890,1074,1001,1199,139,745,935,311,895,1006,425,1380,427,747,655,211,332,2140,656,2794,840,201,2689,572,1441,701,611,2093,126,2884,1271,2417,944,1949,752,660,1017,578,335,851,1748,253,549,2106,1568,1153,760,1713,92,1571,2534,855,721,277,528,2388,810,1760,1574,811,910,1102,767,194,975,259,1293,1038,280 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2937 Ficolin 1 rich granule 47 86 2.916748731696775 0.0035370058275301 P14174,O60610,P07900,P09960,P42785,Q14019,Q9Y6G9,P35573,P28066,O00231,Q86VP6,Q96G03,O43242,P06737,P53396,Q13442,P09429,Q5T4S7,P08238,P35998,Q9NZ32,P25787,O00487,P61586,P18669,Q14004,Q15008,P51665,P37108,P06744,P0DMV9,P11142,P42025,P18206,P13798,Q7Z6Z7,Q16539,Q9UNM6,P17980,Q13200,P46976,P20618,P12956,Q9UJU6,P13639,Q99436,Q13510 Localization GO Cellular component msigdb_gocc 122,488,245,868,6,140,280,880,876,149,296,433,165,534,782,46,415,944,306,686,855,926,560,931,683,569,201,198,688,324,822,823,689,209,208,752,1011,767,362,745,235,735,233,120,872,253,397 149,1106,560,1721,165,488,1585,1678,1359,2172,1836,1055,534,324,1474,245,306,415,868,2403,822,1838,823,2633,1840,233,1887,872,208,122,987,2075,2354,1179,1724,1889,362,209,683,735,1725,926,876,1247,880,686,1423,688,689,6,235,1426,198,782,1485,1934,1067,931,2511,1731,2638,2317,1200,745,46,397,569,140,1693,201,1011,944,1442,2867,752,296,1088,433,253,1027,855,1573,120,767,2673,280 1.3968228224013606,0.24801958368154803,0.6369761233848037,-0.1719280959561597,1.3076973767692464,0.704699791414857,-0.05405313922784484,-0.13234464502495924,0.09914099907683403,-0.5420991063561916,-0.2519914877556342,0.28459191556669194,0.6709474376181863,0.9350551147231273,0.02309828334687722,1.0622595380909912,0.9671485853633185,0.8046697182564764,0.3928095936133701,-0.759418488288081,0.428393191730484,-0.2519914877556342,0.428393191730484,-1.0792715109109947,-0.2519914877556342,1.0935808714347506,-0.29248013870191797,0.3928095936133701,1.155663166669387,1.5420358124097335,0.32091216739564127,-0.4575872142200032,-0.7152427522665485,0.2111917997668451,-0.1719280959561597,-0.29248013870191797,0.8702695242261951,1.155663166669387,0.5337207971688037,0.49884576098804173,-0.1719280959561597,0.35698364577547,0.3928095936133701,0.17410512476192191,0.3928095936133701,0.5337207971688037,0.0612563185418274,0.5337207971688037,0.5337207971688037,4.496753993926139,1.0935808714347506,0.0612563185418274,1.1864283685836194,0.463737560425262,0.02309828334687722,-0.33327939055474815,0.28459191556669194,0.35698364577547,-0.8941728675715074,-0.1719280959561597,-1.0792715109109947,-0.6714285051358926,0.2111917997668451,0.49884576098804173,2.4815800828960706,0.8375726207273704,0.6369761233848037,1.455398437788666,-0.13234464502495924,1.1864283685836194,0.32091216739564127,0.35698364577547,0.0612563185418274,-1.8360492193607452,0.49884576098804173,0.9990456262708737,0.28459191556669194,0.8046697182564764,1.0622595380909912,0.32091216739564127,0.428393191730484,-0.015336908887356353,1.5705949318057502,0.49884576098804173,-1.1265583700744997,1.0307485270519672 2937 Protein targeting 41 96 2.911526015585852 0.0035966795473547 P43307,P07900,Q9NS69,O60830,P55786,Q9UBE0,P40855,P31946,Q9P0J0,P09132,P20645,Q99595,P31150,P30536,O76094,Q9Y2T2,Q15629,P49257,Q9Y4C2,Q10713,Q9UHD1,Q9Y371,Q8N4H5,Q5JRX3,P56589,P37108,Q14108,P62258,O60725,Q7Z6Z7,Q16543,P61011,Q15785,O00170,O14737,O14617,O00203,O95376,P46379,Q9NT62,P63104 Processes and pathways GO Biological process msigdb_gobp 130,245,7,9,135,808,264,385,553,639,25,27,777,160,769,438,39,541,319,179,720,722,60,459,70,688,79,692,323,752,228,476,610,584,470,469,585,731,114,257,507 1041,584,585,469,470,1830,1112,2019,2213,323,9,2570,769,2720,2399,731,1680,1528,1051,2501,245,2071,639,2681,823,1887,1478,25,827,1119,160,777,878,385,1120,688,264,130,114,541,2085,1124,135,70,2882,2409,476,1730,1255,692,1545,507,1068,1937,179,2365,1002,79,1653,789,1136,39,610,228,2583,1996,459,1139,1384,2097,2478,752,60,2520,962,27,1709,1876,7,257,553,2294,808,2057,1101,720,2819,1575,438,722,975,319,2349,2676,2459,1520 0.28459191556669194,0.6027831121744145,0.6027831121744145,0.7382358716884349,0.7382358716884349,-0.2519914877556342,0.24801958368154803,-0.4158281796670899,-0.5848621144923504,0.9350551147231273,4.351275402719301,-0.9859257988083908,0.463737560425262,-1.2709592380232988,-0.759418488288081,0.49884576098804173,-0.13234464502495924,-0.015336908887356353,0.28459191556669194,-0.8941728675715074,1.0622595380909912,-0.4575872142200032,0.5683656165997513,-1.1742638113510904,0.428393191730484,-0.29248013870191797,0.02309828334687722,3.2128208825072786,0.428393191730484,0.24801958368154803,1.33757659471794,0.463737560425262,0.3928095936133701,0.8375726207273704,0.24801958368154803,0.5337207971688037,1.0307485270519672,1.5133178288044788,1.627243250148423,0.6709474376181863,-0.4575872142200032,0.24801958368154803,1.484439279959394,1.9809980490909074,-2.0009314909515403,-0.759418488288081,0.7382358716884349,-0.1719280959561597,0.17410512476192191,0.5337207971688037,-0.015336908887356353,0.704699791414857,0.28459191556669194,-0.33327939055474815,1.2776448956782354,-0.7152427522665485,0.32091216739564127,1.901497527876068,-0.09305436959858496,0.463737560425262,0.24801958368154803,2.6457718362497507,0.6027831121744145,1.1247147016520551,-0.9859257988083908,-0.3743938386878874,0.7715583169098631,0.24801958368154803,0.09914099907683403,-0.4575872142200032,-0.8488775839823314,0.49884576098804173,2.1108177774831414,-0.8941728675715074,0.35698364577547,3.1296290705170495,-0.13234464502495924,-0.2519914877556342,4.432627557673481,1.0622595380909912,0.6709474376181863,-0.6279701240574134,0.463737560425262,-0.4158281796670899,0.28459191556669194,0.5337207971688037,-1.5718746398609995,-0.015336908887356353,0.8046697182564764,0.5337207971688037,0.35698364577547,0.9671485853633185,-0.6714285051358926,-1.1265583700744997,-0.8039614683338043,0.02309828334687722 2937 C type lectin receptors clrs 29 47 2.902264645862628 0.0037047542063921 P49720,Q13177,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,139,876,811,549,149,165,539,578,50,840,919,686,926,560,824,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,1919,165,919,2502,824,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1935,1856,477,1374,1127,1259,2444,890,139,745,1006,840,201,2093,1017,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,-0.8941728675715074,0.428393191730484,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.33327939055474815,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,-0.8039614683338043,0.3928095936133701,1.455398437788666,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,-0.4575872142200032,0.32091216739564127,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Degradation of beta catenin by the destruction complex 31 49 2.8815487991184385 0.0039572595182078 P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,Q13363,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q99436,Q13200,P20618,Q14738,P17980,Q13616 Processes and pathways Reactome Pathways msigdb_reactome 884,502,876,811,549,149,165,539,578,50,840,919,686,926,560,834,201,198,936,326,327,477,105,890,767,253,745,735,656,362,1006 149,1106,560,1353,165,919,362,735,1182,1183,926,1184,1418,876,105,326,327,990,1060,2130,686,1480,539,502,884,50,1251,198,834,2315,1431,1856,477,1374,1127,1259,890,745,936,2609,1006,656,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.3076973767692464,0.35698364577547,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.32091216739564127,0.28459191556669194,-0.4996758503153541,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.704699791414857,0.3928095936133701,2.237423692928971,0.17410512476192191,1.1864283685836194,0.428393191730484,-0.6714285051358926,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.3928095936133701,0.49884576098804173,0.35698364577547,-1.0323962561974658,0.32091216739564127,0.5683656165997513,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Proteasome accessory complex 15 21 2.879382106126905 0.0039845524232517 O00487,O43242,Q16186,P55036,Q9UNM6,Q15008,Q13200,P51665,P48556,Q9UL46,P62191,O00231,Q99460,P17980,P35998 Localization GO Cellular component msigdb_gocc 560,165,515,834,767,201,745,198,539,811,477,149,549,362,686 149,1106,560,165,362,686,1480,539,198,834,1856,477,1374,1127,890,745,201,515,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,1.3076973767692464,0.8702695242261951,0.5337207971688037,0.02309828334687722,0.6709474376181863,1.1864283685836194,0.428393191730484,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,1.1864283685836194,0.704699791414857,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Cellular response to starvation 35 89 2.875562840367588 0.0040330785635656 Q15382,P61254,P42345,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,Q92616,P08243,P05387,P08865,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,P05198,P62829,Q9Y3U8,P62847,P35268,P46782,P46779,P62241 Processes and pathways Reactome Pathways msigdb_reactome 132,136,265,504,505,506,384,387,389,155,650,649,289,423,542,315,307,562,680,682,454,82,83,325,225,95,604,594,607,243,372,367,599,738,743 594,2603,562,1638,307,1414,680,1530,682,874,1477,773,1244,1416,384,1245,325,1419,1644,1931,367,2082,1311,1479,82,387,1645,265,95,389,1189,737,738,1482,599,155,1314,927,1933,2228,504,1197,136,1650,542,1989,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1600,289,1651,1691,1549,1131,132,2867,315,2376,971,1517,243 0.6027831121744145,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.9671485853633185,0.0612563185418274,0.5337207971688037,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.463737560425262,0.17410512476192191,0.0612563185418274,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,-0.4575872142200032,0.1367560507410777,0.02309828334687722,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.0307485270519672,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,-0.5848621144923504,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,-0.3743938386878874,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,1.5133178288044788,-1.8360492193607452,0.9671485853633185,-0.7152427522665485,0.35698364577547,0.02309828334687722,1.0935808714347506 2937 Cytoplasmic translation 50 115 2.869002217571363 0.0041176891168608 P46778,P61254,P42345,P60866,P62081,P62280,Q9Y5A9,P23396,P39023,P46776,P11940,P46783,P62917,P62277,P20042,P83881,Q04637,P62750,P61353,Q14152,P55010,P05387,P67809,P08865,Q06787,P18077,P62906,P62701,Q86U44,O60524,O60506,P39019,P62899,P26373,Q15056,P42766,P61927,P23588,P62829,Q9Y3U8,P62847,Q9H2P9,P41214,P62495,P35268,P46782,P62269,P62910,P46779,P62241 Processes and pathways GO Biological process msigdb_gobp 737,136,265,504,505,506,147,384,387,389,770,155,650,649,773,289,171,423,542,180,421,562,65,680,566,682,835,454,620,818,443,82,83,325,227,95,604,364,607,243,372,524,369,606,367,599,887,888,738,743 1042,1045,443,818,865,2603,562,1638,1414,680,770,987,1978,1530,682,874,1477,773,384,364,1245,325,1419,1644,1931,367,1311,82,387,1645,369,265,95,389,1189,737,738,1482,599,155,1314,927,1192,1933,421,1487,2826,1066,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,606,454,423,1544,607,1792,372,1320,2847,1256,83,835,888,1545,650,2761,2548,65,1600,289,1651,1796,1691,1549,171,566,1131,2580,1437,1862,180,1079,227,1140,1208,620,2193,2107,2525,1874,524,1755,1032,1397,2861,1230,1232,243,147 0.28459191556669194,0.28459191556669194,0.7715583169098631,0.428393191730484,0.3928095936133701,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.0612563185418274,0.5337207971688037,0.463737560425262,0.32091216739564127,-0.3743938386878874,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.463737560425262,0.8375726207273704,0.8702695242261951,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,0.8702695242261951,1.0307485270519672,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,0.2111917997668451,-0.33327939055474815,0.8046697182564764,0.02309828334687722,-1.623692476299974,0.28459191556669194,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.6027831121744145,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,2.0592842445697523,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.21180894066884262,-0.13234464502495924,-0.015336908887356353,1.3076973767692464,0.6369761233848037,0.24801958368154803,-0.9859257988083908,0.0612563185418274,-0.2519914877556342,1.2776448956782354,0.28459191556669194,1.1247147016520551,0.24801958368154803,0.2111917997668451,0.6027831121744145,-0.5420991063561916,-0.4575872142200032,-0.8941728675715074,-0.2519914877556342,0.704699791414857,-0.1719280959561597,0.32091216739564127,0.09914099907683403,-1.7821781247895743,0.2111917997668451,0.2111917997668451,1.0935808714347506,1.4261935465788533 2937 Cell adhesion molecule binding 72 207 2.8619243929219658 0.0042107734237659 P46940,P15311,Q9Y639,P62820,Q13177,P43487,P49327,P26641,Q9UQB8,P31946,Q15019,P55010,Q9Y5K6,Q13813,O60749,Q08722,P62750,P35611,Q09666,Q9H3U1,P26038,Q6PKG0,Q92616,Q9NZZ3,P09429,P35613,Q9Y371,Q9Y490,Q01082,Q9H2G2,Q05682,P08238,P60228,Q14126,P35579,Q9UHX1,P08865,P78344,P62826,Q9H4M9,Q08378,P35241,Q14008,O95433,Q6P996,Q6Y7W6,Q9Y6E2,P62258,P50402,P20073,Q8TCG1,P28072,P18206,Q9UPN3,Q9H0B6,Q86UP2,Q9UJU6,Q15056,Q07157,P78310,P33176,P05198,O60763,O15498,Q16181,Q14C86,Q9C0C2,Q9HC38,P26196,Q9Y266,Q9NQC3,P63104 Functions GO Molecular function msigdb_gomf 131,134,408,395,139,388,503,642,18,385,429,421,440,426,282,424,423,287,543,714,176,575,315,718,415,420,722,723,310,189,59,306,564,570,63,465,680,68,565,340,199,76,697,444,616,617,216,692,330,448,622,326,209,485,92,229,120,227,479,478,473,594,219,346,373,512,523,256,597,121,526,507 1039,725,1352,2630,1721,1630,2813,346,726,978,1634,2397,282,219,1772,1585,2464,1679,2737,444,1528,1412,1176,1836,1473,594,2261,2173,2503,1413,983,984,306,680,415,823,870,872,987,2075,134,1530,1179,2825,209,448,774,2026,2468,2027,2079,1182,2877,176,597,642,2546,326,1185,1592,1187,385,2845,473,1121,2130,76,63,287,420,1424,1932,2029,1646,1727,1368,882,388,1536,2084,1593,131,1787,1314,927,503,1596,330,1933,1426,1853,1196,1317,421,886,564,2088,1650,1791,2637,692,1128,423,395,565,507,1793,478,68,1600,837,310,1859,1549,59,2579,479,199,2412,424,543,1379,2365,1991,139,2232,1003,1941,1005,426,697,570,2581,786,1551,1009,512,429,227,1202,1801,790,1010,1203,373,841,2447,2040,1803,616,575,950,617,1657,2046,1383,1903,1208,229,955,622,2193,1146,1811,797,315,755,2454,1213,1751,1346,1665,853,1348,904,523,92,189,714,340,256,526,1224,907,1623,965,718,2735,1468,1399,1400,465,120,1167,485,18,2628,121,1290,722,1518,723,1628,440,1105,408,216 0.28459191556669194,0.49884576098804173,0.09914099907683403,-1.0792715109109947,-0.1719280959561597,-0.09305436959858496,-1.5718746398609995,0.9027628846125711,0.49884576098804173,0.32091216739564127,-0.09305436959858496,-0.759418488288081,0.9990456262708737,1.1247147016520551,-0.21180894066884262,-0.05405313922784484,-0.8488775839823314,-0.13234464502495924,-1.3199640839408484,0.7715583169098631,-0.015336908887356353,0.0612563185418274,0.2111917997668451,-0.2519914877556342,0.02309828334687722,0.6027831121744145,-0.6279701240574134,-0.5420991063561916,-0.8941728675715074,0.0612563185418274,0.32091216739564127,0.32091216739564127,0.9671485853633185,0.5337207971688037,0.8046697182564764,0.428393191730484,0.3928095936133701,0.3928095936133701,0.32091216739564127,-0.4575872142200032,1.484439279959394,-0.015336908887356353,0.2111917997668451,-1.623692476299974,1.155663166669387,0.7715583169098631,0.463737560425262,-0.4158281796670899,-0.8488775839823314,-0.4158281796670899,-0.4575872142200032,0.2111917997668451,-1.9454153738987696,1.2776448956782354,0.6027831121744145,0.5683656165997513,-0.9398534966833773,0.9350551147231273,0.2111917997668451,-0.05405313922784484,0.2111917997668451,0.8375726207273704,-1.7288348009106087,0.7382358716884349,0.24801958368154803,-0.4996758503153541,1.9281348523770536,2.085115891068643,0.9990456262708737,0.8046697182564764,0.0612563185418274,-0.33327939055474815,-0.4158281796670899,-0.09305436959858496,-0.1719280959561597,0.09914099907683403,0.3928095936133701,0.8375726207273704,-0.015336908887356353,-0.4575872142200032,-0.05405313922784484,1.5133178288044788,-0.21180894066884262,0.1367560507410777,0.35698364577547,0.704699791414857,-0.05405313922784484,0.9350551147231273,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.2111917997668451,0.1367560507410777,0.8046697182564764,0.3928095936133701,0.6369761233848037,-0.4575872142200032,-0.09305436959858496,-0.21180894066884262,-1.0792715109109947,0.5337207971688037,0.24801958368154803,0.8046697182564764,0.8375726207273704,0.6369761233848037,0.704699791414857,-0.21180894066884262,0.7382358716884349,2.0333215775625626,-0.05405313922784484,0.428393191730484,0.9671485853633185,-0.2519914877556342,-0.015336908887356353,2.1363911463999377,-0.9859257988083908,0.7382358716884349,1.1864283685836194,-0.759418488288081,0.8046697182564764,0.6709474376181863,0.09914099907683403,-0.7152427522665485,-0.3743938386878874,1.455398437788666,-0.5848621144923504,0.32091216739564127,-0.33327939055474815,0.32091216739564127,0.8046697182564764,0.5337207971688037,0.6369761233848037,-0.9859257988083908,0.463737560425262,-0.015336908887356353,0.32091216739564127,0.704699791414857,0.8046697182564764,1.1247147016520551,0.2111917997668451,-0.21180894066884262,0.463737560425262,0.32091216739564127,0.2111917997668451,0.8702695242261951,0.428393191730484,-0.8039614683338043,-0.4158281796670899,-0.21180894066884262,0.6027831121744145,0.6369761233848037,0.35698364577547,0.6027831121744145,-0.09305436959858496,-0.4158281796670899,0.09914099907683403,-0.29248013870191797,0.2111917997668451,1.1247147016520551,0.35698364577547,0.6027831121744145,-0.5420991063561916,0.24801958368154803,-0.21180894066884262,0.463737560425262,0.9671485853633185,0.49884576098804173,-0.8039614683338043,0.2111917997668451,-0.1719280959561597,0.1367560507410777,-0.09305436959858496,0.428393191730484,0.1367560507410777,0.3928095936133701,0.704699791414857,1.8207460887469624,1.2474172170623723,0.5337207971688037,0.9350551147231273,1.0622595380909912,0.704699791414857,0.2111917997668451,0.3928095936133701,-0.05405313922784484,0.35698364577547,0.5337207971688037,-1.2709592380232988,0.0612563185418274,0.09914099907683403,0.09914099907683403,0.7715583169098631,1.5705949318057502,0.24801958368154803,0.7382358716884349,3.7962488360202657,-1.0323962561974658,1.5705949318057502,0.17410512476192191,0.5337207971688037,0.02309828334687722,0.5337207971688037,-0.05405313922784484,0.8046697182564764,0.28459191556669194,0.8375726207273704,1.155663166669387 2937 Predicted secreted proteins 9 42 2.8599085516277616 0.0042376318671422 P51858,Q15165,P80303,P26583,Q9HB40,O14786,Q9UMX5,Q02818,P81605 Functions Protein Atlas Protein class protein_atlas_protein_class 58,37,52,86,55,118,26,29,124 118,2542,676,2463,1114,1886,732,1473,324,1413,415,122,1242,1926,86,500,58,783,2742,2926,478,52,124,29,1939,2473,1261,1003,37,1501,707,1610,1704,2236,1026,2336,2382,1668,55,2534,26,2253 1.5705949318057502,-0.9398534966833773,0.5337207971688037,-0.8488775839823314,0.24801958368154803,-0.29248013870191797,0.49884576098804173,0.02309828334687722,0.9350551147231273,0.0612563185418274,0.8046697182564764,1.5420358124097335,0.17410512476192191,-0.33327939055474815,1.8478045517497095,0.704699791414857,2.1363911463999377,0.463737560425262,-1.3199640839408484,-3.311909712172878,0.7382358716884349,2.237423692928971,1.5420358124097335,3.0450375649426276,-0.33327939055474815,-0.8488775839823314,0.17410512476192191,0.32091216739564127,2.691723830472613,0.02309828334687722,0.5337207971688037,-0.05405313922784484,-0.13234464502495924,-0.5848621144923504,0.32091216739564127,-0.6714285051358926,-0.7152427522665485,-0.09305436959858496,2.1871572148884817,-0.8941728675715074,3.192151726462137,-0.5848621144923504 2937 Calmodulin binding 13 35 2.856740604305024 0.0042801546956869 Q01844,P46940,Q13813,P35611,P49327,P35580,Q86VI3,Q07157,Q7Z406,Q01082,P46020,Q05682,P35579 Functions GO Molecular function msigdb_gomf 248,131,426,287,503,113,313,479,119,310,88,59,63 1041,1631,978,2863,1835,2024,1780,2077,1643,63,113,287,88,131,1849,503,310,248,1323,59,479,1605,1736,545,426,790,944,119,313,1751,1709,2493,1100,1672,1294 0.28459191556669194,-0.09305436959858496,0.32091216739564127,-1.8360492193607452,-0.2519914877556342,-0.4158281796670899,-0.21180894066884262,-0.4575872142200032,-0.09305436959858496,2.085115891068643,1.627243250148423,0.9990456262708737,1.8207460887469624,1.5133178288044788,-0.2519914877556342,0.704699791414857,0.9671485853633185,1.0622595380909912,0.1367560507410777,2.1363911463999377,0.7382358716884349,-0.05405313922784484,-0.1719280959561597,0.6709474376181863,0.8046697182564764,0.463737560425262,0.35698364577547,1.5705949318057502,0.9671485853633185,-0.1719280959561597,-0.13234464502495924,-0.8488775839823314,0.28459191556669194,-0.09305436959858496,0.17410512476192191 2937 Pyrimidine containing compound metabolic process 9 29 2.8416326777544616 0.004488317170521 Q9H773,Q9BZX2,Q9NRF8,P04818,P42345,P17812,P34896,Q02252,Q05682 Processes and pathways GO Biological process msigdb_gobp 1,436,138,445,265,447,328,457,59 2302,1056,445,1781,1682,681,447,1725,1591,496,1247,776,1248,879,328,265,930,1858,1548,457,59,938,1898,1457,436,1,1394,138,2429 -0.6714285051358926,0.28459191556669194,0.7715583169098631,-0.21180894066884262,-0.13234464502495924,0.5337207971688037,0.7715583169098631,-0.1719280959561597,-0.05405313922784484,0.704699791414857,0.17410512476192191,0.463737560425262,0.17410512476192191,0.3928095936133701,0.9350551147231273,1.0307485270519672,0.35698364577547,-0.2519914877556342,-0.015336908887356353,0.7715583169098631,2.1363911463999377,0.35698364577547,-0.29248013870191797,0.0612563185418274,0.8046697182564764,5.8748316084197345,0.09914099907683403,1.484439279959394,-0.759418488288081 2937 Srp dependent cotranslational protein targeting to membrane 41 91 2.8300929136475155 0.0046534488017844 P46778,P43307,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P09132,P46783,P62917,P62277,O76094,Q15629,P83881,P62750,P61353,P05387,P08865,P18077,P62906,P62701,P37108,P39019,P62899,P26373,P62861,P61011,P42766,P61927,P62829,Q9Y3U8,P62847,P35268,P62269,P46782,P62910,P46779,P51571,P62241 Processes and pathways Reactome Pathways msigdb_reactome 737,130,136,504,505,506,384,387,389,639,155,650,649,769,39,289,423,542,562,680,682,835,454,688,82,83,325,225,476,95,604,607,243,372,367,887,599,888,738,885,743 769,1238,1304,2603,562,1638,2071,1414,680,639,1530,682,874,1477,384,1245,325,1419,1644,1931,367,1311,688,82,387,2704,1645,95,130,389,1189,737,738,1482,599,155,1314,927,1933,885,2882,504,2409,476,1197,136,1650,542,1432,1730,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,225,1256,83,835,888,1545,650,2761,2548,1375,1600,289,1651,1691,1549,1131,1653,39,1101,243,1520 0.463737560425262,0.17410512476192191,0.1367560507410777,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,-0.4575872142200032,0.0612563185418274,0.5337207971688037,0.5683656165997513,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,0.5337207971688037,1.8747212260962505,0.8375726207273704,-1.222394988641525,-0.09305436959858496,1.7387054861501252,1.5133178288044788,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,0.3928095936133701,-2.0009314909515403,0.704699791414857,-0.759418488288081,0.7382358716884349,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,-0.1719280959561597,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,1.1247147016520551,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,0.09914099907683403,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,-0.09305436959858496,2.6457718362497507,0.28459191556669194,1.0935808714347506,0.02309828334687722 2937 Endothelial cell migration 7 31 2.827992105062519 0.0046840961691563 P09601,P42785,Q8WTV0,P06576,P19174,O14786,P35579 Processes and pathways GO Biological process msigdb_gobp 34,6,10,196,234,118,63 486,118,2814,1114,1473,2261,196,324,415,34,2075,772,234,2178,2080,2546,63,1727,6,1598,1852,931,1731,1077,1861,1011,943,1270,10,1348,1963 0.704699791414857,1.5705949318057502,-1.5718746398609995,0.24801958368154803,0.02309828334687722,-0.6279701240574134,1.1864283685836194,0.9350551147231273,0.8046697182564764,2.871469999732692,-0.4575872142200032,0.463737560425262,1.0935808714347506,-0.5420991063561916,-0.4575872142200032,-0.9398534966833773,2.085115891068643,-0.1719280959561597,4.496753993926139,-0.05405313922784484,-0.2519914877556342,0.35698364577547,-0.1719280959561597,0.28459191556669194,-0.2519914877556342,0.32091216739564127,0.35698364577547,0.17410512476192191,4.351275402719301,0.1367560507410777,-0.33327939055474815 2937 Translation factors 28 37 2.824431120526385 0.004736462751157 P49770,P26641,Q9UI10,Q14240,O75821,P11940,O75153,P20042,Q05639,P55884,Q04637,Q14152,P55010,P60228,O60841,O15371,P63241,Q14232,Q15056,Q13144,P05198,Q9NR50,O75822,P62495,P23588,P13639,O15372,P24534 Processes and pathways WikiPathways msigdb_wp 994,642,809,1079,153,770,24,773,1073,784,171,180,421,564,303,1042,836,939,227,893,594,1032,729,606,364,872,862,989 1521,1042,862,1675,303,24,153,729,594,1778,770,872,1532,773,364,989,642,1185,994,421,784,2826,564,1066,606,836,171,1073,893,1437,180,939,1079,227,1874,1032,809 -0.015336908887356353,0.28459191556669194,0.3928095936133701,-0.13234464502495924,0.9671485853633185,3.2743225522030306,1.3672844525092513,0.49884576098804173,0.6027831121744145,-0.21180894066884262,0.463737560425262,0.3928095936133701,-0.015336908887356353,0.463737560425262,0.8702695242261951,0.32091216739564127,0.5683656165997513,0.2111917997668451,0.32091216739564127,0.8046697182564764,0.463737560425262,-1.623692476299974,0.6369761233848037,0.28459191556669194,0.6027831121744145,0.428393191730484,1.3076973767692464,0.28459191556669194,0.3928095936133701,0.0612563185418274,1.2776448956782354,0.35698364577547,0.28459191556669194,1.1247147016520551,-0.2519914877556342,0.32091216739564127,0.463737560425262 2937 Copi mediated anterograde transport 27 47 2.82396573744028 0.0047433455214838 Q8N6T3,P62820,Q9Y6G9,P61163,Q9Y678,P53621,Q13813,O75935,P48444,Q92538,Q13409,Q01082,Q15363,P04350,Q9NZ32,O43237,P24390,Q14204,P84085,P18085,Q14203,P61923,O60763,O15498,Q13885,Q9BVK6,Q9UJW0 Processes and pathways Reactome Pathways msigdb_reactome 401,395,280,393,813,783,426,283,538,579,311,310,700,305,855,182,67,332,694,825,211,96,219,346,747,521,528 1236,346,182,219,283,305,825,67,1188,1985,2226,1787,538,993,1196,1485,783,1486,393,96,395,2511,694,310,2412,2365,2232,311,895,426,747,211,332,1330,700,401,579,2379,1568,1153,521,855,1286,528,1104,813,280 0.17410512476192191,0.9027628846125711,1.2474172170623723,1.1247147016520551,0.9990456262708737,0.9671485853633185,0.428393191730484,2.0333215775625626,0.2111917997668451,-0.3743938386878874,-0.5848621144923504,-0.21180894066884262,0.6709474376181863,0.32091216739564127,0.2111917997668451,0.02309828334687722,0.463737560425262,0.02309828334687722,0.8375726207273704,1.7387054861501252,0.8375726207273704,-0.8941728675715074,0.5337207971688037,0.9671485853633185,-0.759418488288081,-0.7152427522665485,-0.5848621144923504,0.9671485853633185,0.3928095936133701,0.8046697182564764,0.49884576098804173,1.155663166669387,0.9350551147231273,0.1367560507410777,0.5337207971688037,0.8375726207273704,0.6369761233848037,-0.7152427522665485,-0.015336908887356353,0.24801958368154803,0.704699791414857,0.428393191730484,0.17410512476192191,0.704699791414857,0.28459191556669194,0.463737560425262,1.0307485270519672 2937 Parkinubiquitin proteasomal system pathway 27 33 2.8230223231328604 0.0047573259050459 P34932,O00231,Q99460,Q9UNE7,O43242,P48556,O75832,P04350,P22314,P35998,O00487,P55036,Q15008,P68036,P51665,Q0VDF9,P0DMV9,P11142,P07437,P62191,Q9BVA1,Q9UNM6,Q13885,Q13200,O00232,P17980,Q13616 Processes and pathways WikiPathways msigdb_wp 1120,149,549,1102,165,539,919,305,924,686,560,834,201,1068,198,695,822,823,1057,477,1153,767,747,745,1106,362,1006 149,1106,560,1631,165,919,305,1057,822,823,362,924,1120,686,2660,1480,539,198,834,477,1374,1127,1068,695,745,1006,747,201,549,1568,1153,1102,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,-0.09305436959858496,1.3076973767692464,0.35698364577547,0.9671485853633185,0.28459191556669194,0.428393191730484,0.428393191730484,0.8702695242261951,0.35698364577547,0.24801958368154803,0.5337207971688037,-1.1265583700744997,0.02309828334687722,0.6709474376181863,1.1864283685836194,0.428393191730484,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.28459191556669194,0.5337207971688037,0.49884576098804173,0.32091216739564127,0.49884576098804173,1.1864283685836194,0.6709474376181863,-0.015336908887356353,0.24801958368154803,0.28459191556669194,0.49884576098804173 2937 Cell recognition 8 22 2.8199532077059963 0.0048030652761252 Q9Y639,Q8WTV0,P26038,Q14157,P35613,O14786,P45880,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 408,10,176,116,420,118,329,526 118,2122,2395,1836,734,176,420,1312,329,1250,1191,1426,1252,507,1260,116,1271,10,1811,1456,526,408 1.5705949318057502,-0.4996758503153541,-0.759418488288081,-0.2519914877556342,0.49884576098804173,1.2776448956782354,0.8046697182564764,0.1367560507410777,0.9350551147231273,0.17410512476192191,0.2111917997668451,0.0612563185418274,0.17410512476192191,0.704699791414857,0.17410512476192191,1.627243250148423,0.17410512476192191,4.351275402719301,-0.21180894066884262,0.0612563185418274,0.704699791414857,0.8375726207273704 2937 Negative regulation of supramolecular fiber organization 17 42 2.8175246742939803 0.0048395396002831 O75122,Q13813,P61758,Q13177,P35241,P35611,Q9UBN7,P16949,Q92974,Q9NUQ9,P35080,Q9UHV9,Q01082,Q07157,P04350,Q13045,Q9BTW9 Processes and pathways GO Biological process msigdb_gobp 471,426,453,139,76,287,80,143,519,128,366,484,310,479,305,226,163 816,471,1114,305,983,823,143,1182,1309,366,76,287,645,2226,1787,1196,1318,601,453,2511,310,509,479,1379,226,139,2318,426,1010,1706,519,799,853,1348,163,128,1963,80,1100,1399,484,2887 0.428393191730484,0.7382358716884349,0.24801958368154803,0.9671485853633185,0.32091216739564127,0.428393191730484,1.4261935465788533,0.2111917997668451,0.1367560507410777,0.8702695242261951,1.9281348523770536,0.9990456262708737,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,0.1367560507410777,0.6027831121744145,0.7715583169098631,-0.8941728675715074,0.9671485853633185,0.704699791414857,0.7382358716884349,0.09914099907683403,1.1247147016520551,1.455398437788666,-0.6714285051358926,0.8046697182564764,0.32091216739564127,-0.13234464502495924,0.704699791414857,0.463737560425262,0.428393191730484,0.1367560507410777,1.33757659471794,1.5420358124097335,-0.33327939055474815,1.901497527876068,0.28459191556669194,0.09914099907683403,0.7382358716884349,-2.0009314909515403 2937 Cadherin binding 63 189 2.814698484171002 0.0048823017593626 P46940,P15311,P62820,Q13177,P43487,P49327,P26641,Q9UQB8,P31946,Q15019,Q9Y5K6,Q13813,O60749,P62750,P35611,Q09666,Q9H3U1,Q6PKG0,Q92616,Q9NZZ3,P35613,P55010,Q9Y371,Q9Y490,Q01082,Q9H2G2,Q05682,P08238,P60228,P35579,Q9UHX1,P78344,P62826,Q9H4M9,Q08378,P35241,Q14008,O95433,Q6P996,Q6Y7W6,Q9Y6E2,P50402,Q8TCG1,P28072,P18206,Q9UPN3,Q9H0B6,Q86UP2,Q9UJU6,Q15056,Q07157,P33176,P05198,O60763,O15498,Q16181,Q14C86,Q9C0C2,Q9HC38,P26196,Q9Y266,Q9NQC3,P63104 Functions GO Molecular function msigdb_gomf 131,134,395,139,388,503,642,18,385,429,440,426,282,423,287,543,714,575,315,718,420,421,722,723,310,189,59,306,564,63,465,68,565,340,199,76,697,444,616,617,216,330,622,326,209,485,92,229,120,227,479,473,594,219,346,373,512,523,256,597,121,526,507 1039,725,1352,2630,1721,1630,2813,346,978,1634,2397,282,219,1772,1585,2464,1679,2737,444,1528,1412,1176,1836,1473,594,2261,2173,1413,983,984,306,823,872,987,2075,134,1530,2825,209,774,2026,2468,2027,2079,1182,2877,597,642,326,1185,1592,1187,385,2845,473,1121,2130,76,63,287,420,1424,1932,2029,1646,1727,1368,882,388,1536,2084,131,1787,1314,927,503,1596,330,1933,1426,1853,1196,1317,421,886,564,2088,1650,1791,2637,692,1128,423,395,565,507,1793,68,1600,837,310,1859,1549,59,2579,479,199,2412,543,1379,2365,1991,139,2232,1941,1005,426,697,2581,786,1551,1009,512,429,227,1202,1801,790,1010,1203,373,841,2447,2040,1803,616,575,950,617,1657,2046,1383,1903,1208,229,955,622,2193,1146,797,315,2454,1213,1751,1346,1665,853,1348,904,523,92,189,714,340,256,526,1224,907,1623,965,718,2735,1468,1399,1400,465,120,1167,485,18,2628,121,722,1518,723,1628,440,1105,216 0.28459191556669194,0.49884576098804173,0.09914099907683403,-1.0792715109109947,-0.1719280959561597,-0.09305436959858496,-1.5718746398609995,0.9027628846125711,0.32091216739564127,-0.09305436959858496,-0.759418488288081,0.9990456262708737,1.1247147016520551,-0.21180894066884262,-0.05405313922784484,-0.8488775839823314,-0.13234464502495924,-1.3199640839408484,0.7715583169098631,-0.015336908887356353,0.0612563185418274,0.2111917997668451,-0.2519914877556342,0.02309828334687722,0.6027831121744145,-0.6279701240574134,-0.5420991063561916,0.0612563185418274,0.32091216739564127,0.32091216739564127,0.9671485853633185,0.428393191730484,0.3928095936133701,0.32091216739564127,-0.4575872142200032,1.484439279959394,-0.015336908887356353,-1.623692476299974,1.155663166669387,0.463737560425262,-0.4158281796670899,-0.8488775839823314,-0.4158281796670899,-0.4575872142200032,0.2111917997668451,-1.9454153738987696,0.6027831121744145,0.5683656165997513,0.9350551147231273,0.2111917997668451,-0.05405313922784484,0.2111917997668451,0.8375726207273704,-1.7288348009106087,0.7382358716884349,0.24801958368154803,-0.4996758503153541,1.9281348523770536,2.085115891068643,0.9990456262708737,0.8046697182564764,0.0612563185418274,-0.33327939055474815,-0.4158281796670899,-0.09305436959858496,-0.1719280959561597,0.09914099907683403,0.3928095936133701,0.8375726207273704,-0.015336908887356353,-0.4575872142200032,1.5133178288044788,-0.21180894066884262,0.1367560507410777,0.35698364577547,0.704699791414857,-0.05405313922784484,0.9350551147231273,-0.33327939055474815,0.0612563185418274,-0.2519914877556342,0.2111917997668451,0.1367560507410777,0.8046697182564764,0.3928095936133701,0.6369761233848037,-0.4575872142200032,-0.09305436959858496,-0.21180894066884262,-1.0792715109109947,0.5337207971688037,0.24801958368154803,0.8046697182564764,0.8375726207273704,0.6369761233848037,0.704699791414857,-0.21180894066884262,2.0333215775625626,-0.05405313922784484,0.428393191730484,0.9671485853633185,-0.2519914877556342,-0.015336908887356353,2.1363911463999377,-0.9859257988083908,0.7382358716884349,1.1864283685836194,-0.759418488288081,0.6709474376181863,0.09914099907683403,-0.7152427522665485,-0.3743938386878874,1.455398437788666,-0.5848621144923504,-0.33327939055474815,0.32091216739564127,0.8046697182564764,0.5337207971688037,-0.9859257988083908,0.463737560425262,-0.015336908887356353,0.32091216739564127,0.704699791414857,0.8046697182564764,1.1247147016520551,0.2111917997668451,-0.21180894066884262,0.463737560425262,0.32091216739564127,0.2111917997668451,0.8702695242261951,0.428393191730484,-0.8039614683338043,-0.4158281796670899,-0.21180894066884262,0.6027831121744145,0.6369761233848037,0.35698364577547,0.6027831121744145,-0.09305436959858496,-0.4158281796670899,0.09914099907683403,-0.29248013870191797,0.2111917997668451,1.1247147016520551,0.35698364577547,0.6027831121744145,-0.5420991063561916,0.24801958368154803,0.463737560425262,0.9671485853633185,-0.8039614683338043,0.2111917997668451,-0.1719280959561597,0.1367560507410777,-0.09305436959858496,0.428393191730484,0.1367560507410777,0.3928095936133701,0.704699791414857,1.8207460887469624,1.2474172170623723,0.5337207971688037,0.9350551147231273,1.0622595380909912,0.704699791414857,0.2111917997668451,0.3928095936133701,-0.05405313922784484,0.35698364577547,0.5337207971688037,-1.2709592380232988,0.0612563185418274,0.09914099907683403,0.09914099907683403,0.7715583169098631,1.5705949318057502,0.24801958368154803,0.7382358716884349,3.7962488360202657,-1.0323962561974658,1.5705949318057502,0.5337207971688037,0.02309828334687722,0.5337207971688037,-0.05405313922784484,0.8046697182564764,0.28459191556669194,1.155663166669387 2937 Calmodulin-binding 12 32 2.8035881604406465 0.0050537413578353 Q01844,P46940,Q13813,P35611,P35580,Q86VI3,Q07157,Q7Z406,Q01082,P46020,Q05682,P35579 Functions Protein Atlas Molecular function protein_atlas_molecular_function 248,131,426,287,113,313,479,119,310,88,59,63 1041,1631,978,2863,2024,1780,2077,1643,63,113,287,88,131,1849,310,248,1323,59,479,1605,1736,545,426,790,944,119,313,1751,2493,1100,1672,1294 0.28459191556669194,-0.09305436959858496,0.32091216739564127,-1.8360492193607452,-0.4158281796670899,-0.21180894066884262,-0.4575872142200032,-0.09305436959858496,2.085115891068643,1.627243250148423,0.9990456262708737,1.8207460887469624,1.5133178288044788,-0.2519914877556342,0.9671485853633185,1.0622595380909912,0.1367560507410777,2.1363911463999377,0.7382358716884349,-0.05405313922784484,-0.1719280959561597,0.6709474376181863,0.8046697182564764,0.463737560425262,0.35698364577547,1.5705949318057502,0.9671485853633185,-0.1719280959561597,-0.8488775839823314,0.28459191556669194,-0.09305436959858496,0.17410512476192191 2937 Diseases of signal transduction by growth factor receptors and second messengers 49 140 2.797442026250027 0.0051509010173698 P46940,P07900,P62140,P48729,P26641,P42345,P31946,Q99460,O00231,Q99956,O43242,O94979,P48556,Q92530,P26038,P49721,O15164,Q9Y490,Q01082,P35998,P35579,O00487,Q9HC35,Q15008,P51665,Q9UBN7,Q9NRY5,Q14203,P28072,P18206,P28074,P62191,Q16543,Q16630,P33176,P28070,Q9UNM6,P12270,Q99436,Q13200,O00203,P62993,P19174,P41240,Q14738,P40763,P17980,Q06330,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 131,245,394,502,642,265,385,549,149,712,165,284,539,578,176,50,411,723,310,686,63,560,341,201,198,80,84,211,326,209,327,477,228,349,473,105,767,104,253,745,585,236,234,370,656,598,362,125,508 585,149,1106,1969,560,1353,411,1832,165,2168,2863,2823,919,2068,284,1359,1680,2502,980,1976,2070,245,1529,1306,104,362,209,234,1642,1361,735,2178,2079,1785,1182,1183,926,1184,1418,176,642,828,876,105,326,327,1247,2355,877,990,1060,1929,878,1187,385,832,473,2130,2081,63,686,1846,2755,598,370,1727,265,1480,131,539,502,1483,884,50,1891,1251,1371,1852,198,834,1934,2315,1431,1856,394,477,1374,1127,2361,1544,1257,236,1259,2136,1733,508,310,1071,2579,890,125,1074,2708,745,936,2318,2609,1605,1736,1006,211,656,1330,840,201,228,349,1996,950,1657,1903,1141,578,1612,2485,2151,1455,253,549,712,341,1283,84,1963,1099,80,1627,811,767,723 0.6027831121744145,1.3968228224013606,0.24801958368154803,-0.3743938386878874,0.6369761233848037,0.09914099907683403,0.8046697182564764,-0.2519914877556342,1.3076973767692464,-0.5420991063561916,-1.8360492193607452,-1.623692476299974,0.35698364577547,-0.4575872142200032,0.9990456262708737,0.09914099907683403,-0.13234464502495924,-0.8941728675715074,0.32091216739564127,-0.3743938386878874,-0.4575872142200032,1.0622595380909912,-0.015336908887356353,0.1367560507410777,1.6832758718136789,0.8702695242261951,1.155663166669387,1.0935808714347506,-0.09305436959858496,0.09914099907683403,0.49884576098804173,-0.5420991063561916,-0.4575872142200032,-0.21180894066884262,0.2111917997668451,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,1.2776448956782354,0.5683656165997513,0.428393191730484,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.17410512476192191,-0.7152427522665485,0.3928095936133701,0.32091216739564127,0.28459191556669194,-0.33327939055474815,0.3928095936133701,0.2111917997668451,0.8375726207273704,0.428393191730484,0.7382358716884349,-0.4996758503153541,-0.4575872142200032,2.085115891068643,0.5337207971688037,-0.2519914877556342,-1.3694172456596465,0.6027831121744145,0.8702695242261951,-0.1719280959561597,1.0307485270519672,0.02309828334687722,1.5133178288044788,0.6709474376181863,0.704699791414857,0.02309828334687722,0.3928095936133701,2.237423692928971,-0.29248013870191797,0.17410512476192191,0.09914099907683403,-0.2519914877556342,1.1864283685836194,0.428393191730484,-0.33327939055474815,-0.6714285051358926,0.0612563185418274,-0.2519914877556342,0.8375726207273704,0.7382358716884349,0.09914099907683403,0.24801958368154803,-0.7152427522665485,-0.015336908887356353,0.17410512476192191,1.0935808714347506,0.17410512476192191,-0.4996758503153541,-0.1719280959561597,0.704699791414857,0.9671485853633185,0.28459191556669194,-0.9859257988083908,0.3928095936133701,1.5420358124097335,0.28459191556669194,-1.222394988641525,0.49884576098804173,0.35698364577547,-0.6714285051358926,-1.0323962561974658,-0.05405313922784484,-0.1719280959561597,0.32091216739564127,1.155663166669387,0.5683656165997513,0.1367560507410777,0.428393191730484,1.1864283685836194,1.1247147016520551,0.9027628846125711,-0.3743938386878874,0.35698364577547,-0.09305436959858496,-0.29248013870191797,0.24801958368154803,0.6369761233848037,-0.05405313922784484,-0.8488775839823314,-0.4996758503153541,0.0612563185418274,1.0622595380909912,0.6709474376181863,0.5337207971688037,0.9350551147231273,0.17410512476192191,1.8747212260962505,-0.33327939055474815,0.28459191556669194,1.901497527876068,-0.05405313922784484,0.463737560425262,0.49884576098804173,0.5337207971688037 2937 Transporter 38 160 2.7909236052089352 0.0052557875736181 O43772,Q9HD45,P08183,Q8IXU6,P37198,O95563,Q9Y6M7,O95342,Q9UIA9,Q96A65,P53985,Q6N075,Q14444,Q7Z7H5,Q70HW3,Q92973,O94979,P09496,O60749,P48444,Q9BQE5,P48739,P49257,Q9H2D1,Q96NB2,P24390,Q00169,P06576,P56385,Q92544,P61923,Q8N1F7,O60763,O14617,Q9BVK6,P24539,Q9UPT5,Q00610 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 4,274,8,11,386,262,148,22,554,300,161,30,428,162,294,432,284,535,282,538,43,540,541,188,338,67,455,196,451,91,96,350,219,469,521,365,529,508 2907,2801,585,916,1766,1168,1236,469,2015,2016,1406,2065,4,2066,1634,1635,282,219,636,1773,2303,2499,284,1237,2737,22,1303,262,2501,2069,2305,196,8,984,535,1837,2353,2633,2125,2306,1887,1243,2077,1244,1416,67,365,2080,1308,2179,1928,1188,1684,386,1479,538,540,541,993,1124,1728,996,2031,2509,1485,783,1599,161,1729,2227,1987,1486,1429,2228,1430,451,1988,1989,1730,96,1546,2036,455,1795,508,1938,2137,2412,1001,2666,892,2232,1941,1005,428,1693,896,2092,700,1136,1334,30,2044,2556,294,2097,162,11,350,2670,1502,1503,1611,623,2484,2764,1953,91,2621,432,1088,300,2376,338,581,1344,1752,1024,1564,43,1509,1753,626,521,1218,188,1669,1394,274,2734,718,2735,1285,856,1286,719,1398,971,554,1965,2208,529,1716,1104,1719,2391,2392,813,768,148 -2.3464041162208487,-1.5205468840168608,0.6027831121744145,0.35698364577547,-0.21180894066884262,0.2111917997668451,0.17410512476192191,0.7382358716884349,-0.4158281796670899,-0.4158281796670899,0.0612563185418274,-0.4575872142200032,4.835200926172848,-0.4575872142200032,-0.09305436959858496,-0.09305436959858496,0.9990456262708737,1.1247147016520551,0.5683656165997513,-0.21180894066884262,-0.6714285051358926,-0.8941728675715074,0.9990456262708737,0.17410512476192191,-1.3199640839408484,3.513047173839545,0.1367560507410777,1.0307485270519672,-0.8941728675715074,-0.4575872142200032,-0.6714285051358926,1.1864283685836194,4.383977831042348,0.32091216739564127,0.6709474376181863,-0.2519914877556342,-0.7152427522665485,-1.0792715109109947,-0.4996758503153541,-0.6714285051358926,-0.29248013870191797,0.17410512476192191,-0.4575872142200032,0.17410512476192191,0.0612563185418274,2.0333215775625626,0.8702695242261951,-0.4575872142200032,0.1367560507410777,-0.5420991063561916,-0.33327939055474815,0.2111917997668451,-0.13234464502495924,0.8375726207273704,0.02309828334687722,0.6709474376181863,0.6709474376181863,0.6709474376181863,0.32091216739564127,0.24801958368154803,-0.1719280959561597,0.32091216739564127,-0.4158281796670899,-0.8941728675715074,0.02309828334687722,0.463737560425262,-0.05405313922784484,1.33757659471794,-0.1719280959561597,-0.5848621144923504,-0.3743938386878874,0.02309828334687722,0.0612563185418274,-0.5848621144923504,0.0612563185418274,0.7715583169098631,-0.3743938386878874,-0.3743938386878874,-0.1719280959561597,1.7387054861501252,-0.015336908887356353,-0.4158281796670899,0.7715583169098631,-0.21180894066884262,0.704699791414857,-0.33327939055474815,-0.4996758503153541,-0.759418488288081,0.32091216739564127,-1.1265583700744997,0.3928095936133701,-0.5848621144923504,-0.33327939055474815,0.32091216739564127,0.8046697182564764,-0.13234464502495924,0.3928095936133701,-0.4575872142200032,0.5337207971688037,0.24801958368154803,0.1367560507410777,3.0450375649426276,-0.4158281796670899,-0.9398534966833773,0.9990456262708737,-0.4575872142200032,1.33757659471794,4.318354335440558,0.9027628846125711,-1.1265583700744997,0.02309828334687722,0.02309828334687722,-0.05405313922784484,0.6027831121744145,-0.8488775839823314,-1.3694172456596465,-0.33327939055474815,1.8207460887469624,-1.0323962561974658,0.8046697182564764,0.28459191556669194,0.9990456262708737,-0.7152427522665485,0.9350551147231273,0.6369761233848037,0.1367560507410777,-0.1719280959561597,0.32091216739564127,-0.015336908887356353,2.5525992591256026,0.02309828334687722,-0.1719280959561597,0.6027831121744145,0.704699791414857,0.2111917997668451,1.2474172170623723,-0.09305436959858496,0.09914099907683403,1.0307485270519672,-1.2709592380232988,0.5337207971688037,-1.2709592380232988,0.17410512476192191,0.428393191730484,0.17410512476192191,0.5337207971688037,0.09914099907683403,0.35698364577547,0.6709474376181863,-0.33327939055474815,-0.5420991063561916,0.704699791414857,-0.13234464502495924,0.28459191556669194,-0.13234464502495924,-0.7152427522665485,-0.7152427522665485,0.463737560425262,0.49884576098804173,1.4261935465788533 2937 Regulation of cell shape 7 26 2.78604419134925 0.0053355597298683 P15311,O75844,P35241,Q9UQB8,P35580,Q7Z406,P35579 Processes and pathways GO Biological process msigdb_gobp 134,102,76,18,113,119,63 1108,488,1972,2022,102,1836,1473,2865,1780,134,176,76,63,113,931,2511,1733,1942,373,2046,1698,119,2047,755,18,2115 0.24801958368154803,0.704699791414857,-0.3743938386878874,-0.4158281796670899,1.6832758718136789,-0.2519914877556342,0.02309828334687722,-1.8360492193607452,-0.21180894066884262,1.484439279959394,1.2776448956782354,1.9281348523770536,2.085115891068643,1.627243250148423,0.35698364577547,-0.8941728675715074,-0.1719280959561597,-0.33327939055474815,0.8702695242261951,-0.4158281796670899,-0.13234464502495924,1.5705949318057502,-0.4158281796670899,0.49884576098804173,3.7962488360202657,-0.4575872142200032 2937 Proteasome regulatory particle 13 18 2.781571326011325 0.0054096442016418 O00487,O43242,Q16186,Q9UNM6,Q15008,Q13200,P51665,P48556,P62191,Q99460,O00231,P17980,P35998 Localization GO Cellular component msigdb_gocc 560,165,515,767,201,745,198,539,477,549,149,362,686 149,1106,560,165,362,686,1480,539,198,834,477,1374,1127,745,201,515,549,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,1.3076973767692464,0.8702695242261951,0.5337207971688037,0.02309828334687722,0.6709474376181863,1.1864283685836194,0.428393191730484,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.49884576098804173,1.1864283685836194,0.704699791414857,0.6709474376181863,0.49884576098804173 2937 Peptidase activity 23 114 2.780262077023947 0.0054315044367443 O14773,P42785,Q9UIQ6,P55786,Q9BT78,Q9H3G5,Q4J6C6,Q10713,P49721,Q9HB40,Q9UPU5,Q969V3,P51665,Q96KP4,P28072,P13798,P28070,P42892,O75844,Q9NY33,Q16740,Q99436,P81605 Functions GO Molecular function msigdb_gomf 129,6,277,135,272,17,33,179,50,55,191,337,198,213,326,208,105,106,102,240,237,253,124 1521,560,129,862,1882,917,2570,102,1775,2257,1636,1357,920,732,982,1474,868,2073,1058,208,1242,1180,735,1363,1418,105,326,327,2469,2028,2741,1685,687,1932,1312,6,106,1481,1594,884,50,1850,780,198,2686,1986,2407,997,998,135,1431,2409,1375,124,179,2268,427,2320,1606,1653,237,33,1204,459,1947,1999,947,1496,2648,431,2275,1274,621,2189,2916,1612,1387,2281,1212,754,959,1388,337,1615,2886,1148,1276,798,213,1345,253,962,1346,1709,482,272,1028,17,1668,2528,55,2529,629,2716,240,2534,2294,277,191,673,2873,1295,1233,1296 -0.015336908887356353,0.6369761233848037,1.5133178288044788,0.3928095936133701,-0.29248013870191797,0.35698364577547,-0.9859257988083908,1.6832758718136789,-0.21180894066884262,-0.6279701240574134,-0.09305436959858496,0.09914099907683403,0.35698364577547,0.49884576098804173,0.32091216739564127,0.02309828334687722,0.3928095936133701,-0.4575872142200032,0.28459191556669194,1.155663166669387,0.17410512476192191,0.2111917997668451,0.49884576098804173,0.09914099907683403,0.0612563185418274,1.6832758718136789,0.9350551147231273,0.9350551147231273,-0.8488775839823314,-0.4158281796670899,-1.3199640839408484,-0.13234464502495924,0.5337207971688037,-0.33327939055474815,0.1367560507410777,4.496753993926139,1.6832758718136789,0.02309828334687722,-0.05405313922784484,0.3928095936133701,2.237423692928971,-0.2519914877556342,0.463737560425262,1.1864283685836194,-1.1742638113510904,-0.3743938386878874,-0.759418488288081,0.32091216739564127,0.32091216739564127,1.484439279959394,0.0612563185418274,-0.759418488288081,0.09914099907683403,1.5420358124097335,1.2776448956782354,-0.6279701240574134,0.8046697182564764,-0.6714285051358926,-0.05405313922784484,-0.09305436959858496,1.0935808714347506,2.959000560087587,0.2111917997668451,0.7715583169098631,-0.33327939055474815,-0.3743938386878874,0.35698364577547,0.02309828334687722,-1.0792715109109947,0.8046697182564764,-0.6279701240574134,0.17410512476192191,0.6027831121744145,-0.5420991063561916,-2.589360161351481,-0.05405313922784484,0.09914099907683403,-0.6279701240574134,0.2111917997668451,0.49884576098804173,0.35698364577547,0.09914099907683403,0.9350551147231273,-0.05405313922784484,-2.0009314909515403,0.24801958368154803,0.17410512476192191,0.463737560425262,1.155663166669387,0.1367560507410777,1.0622595380909912,0.35698364577547,0.1367560507410777,-0.13234464502495924,0.7382358716884349,1.0307485270519672,0.32091216739564127,3.7962488360202657,-0.09305436959858496,-0.8941728675715074,2.1871572148884817,-0.8941728675715074,0.6027831121744145,-1.222394988641525,1.0935808714347506,-0.8941728675715074,-0.6279701240574134,1.0307485270519672,1.2474172170623723,0.5683656165997513,-1.8904581760074333,0.17410512476192191,0.2111917997668451,0.17410512476192191 2937 Receptor mediated endocytosis 17 49 2.7757120791892627 0.0055080962637974 Q9Y5K6,P20339,Q9UQ16,O75165,P09496,P15311,P50570,Q99700,Q13614,Q5VW38,Q14108,P50897,P62993,Q9UJU6,P20645,Q00610,P30533 Processes and pathways GO Biological process msigdb_gobp 440,563,194,220,535,134,308,353,110,15,79,49,236,120,25,508,183 1969,1831,1471,220,2657,1678,1411,732,2261,1413,535,1837,1178,134,563,25,2079,2128,183,832,882,308,49,1599,1791,236,1546,508,932,566,1941,1005,110,2270,79,2581,786,2092,15,842,2649,1748,353,714,120,2297,194,440,1105 -0.3743938386878874,-0.2519914877556342,0.02309828334687722,1.1247147016520551,-1.1265583700744997,-0.13234464502495924,0.0612563185418274,0.49884576098804173,-0.6279701240574134,0.0612563185418274,0.6709474376181863,-0.2519914877556342,0.2111917997668451,1.484439279959394,0.6369761233848037,3.2128208825072786,-0.4575872142200032,-0.4996758503153541,1.2474172170623723,0.428393191730484,0.3928095936133701,0.9671485853633185,2.3364949483641926,-0.05405313922784484,-0.21180894066884262,1.0935808714347506,-0.015336908887356353,0.704699791414857,0.35698364577547,0.6369761233848037,-0.33327939055474815,0.32091216739564127,1.655335720828877,-0.6279701240574134,1.901497527876068,-0.9859257988083908,0.463737560425262,-0.4575872142200032,3.994138285325319,0.428393191730484,-1.0792715109109947,-0.1719280959561597,0.9027628846125711,0.5337207971688037,1.5705949318057502,-0.6279701240574134,1.2170123744522818,0.8046697182564764,0.28459191556669194 2937 Golgi apparatus 74 262 2.751719027993508 0.0059283360901352 O00443,O14773,Q8N6T3,Q15382,P62820,Q9H7Z7,P42345,P49327,Q5VW38,P42858,Q9UQB8,Q5VYK3,Q8IUR0,O95342,Q99986,P20645,Q96SU4,Q02818,Q86VP6,Q7Z7H5,Q4J6C6,Q9Y2T2,P09496,O95197,P48444,P48739,P49257,O14828,Q10713,P50897,P53367,P80303,Q92538,Q6ZRP7,Q9NR31,O15118,Q8TBA6,P50570,P35613,P31948,P30533,Q9UQ16,Q15392,P24390,Q8TD16,Q14004,Q9UJY4,Q16706,Q08378,Q9Y282,Q6P996,Q14108,O15127,O43852,Q96A49,Q9UPN3,Q92544,Q99700,Q9BTU6,P61923,O75122,O60763,O00429,O14617,O15498,Q16799,P62993,Q92974,P04439,Q9BVK6,Q9UJU6,Q9Y266,O95456,Q00610 Localization GO Cellular component msigdb_gocc 486,129,401,132,395,141,265,503,15,144,18,270,548,22,550,25,301,29,296,162,33,438,535,532,538,540,541,281,179,49,51,52,579,576,582,173,314,308,420,418,183,194,202,67,205,569,466,612,199,81,616,79,320,322,212,485,91,353,354,96,471,219,345,469,346,111,236,519,232,521,120,121,360,508 2432,585,1969,345,486,1236,469,2497,1523,129,281,1831,1109,173,320,1769,1970,346,2063,2678,1172,588,1471,978,1299,322,2542,1634,219,471,1924,1677,865,2599,2870,532,2737,22,360,2680,2815,1411,1412,1053,2502,1054,981,232,2069,2262,2123,2703,535,1837,2739,1415,2353,1178,1724,1180,734,825,25,2026,596,1059,2079,67,1182,1245,828,2546,1247,2469,183,777,418,1188,420,1310,2682,1846,992,265,144,1985,538,540,541,503,993,1195,308,1538,49,2085,1598,1124,1125,1728,996,647,51,1485,783,997,2086,691,1254,2230,2088,1542,96,395,236,52,694,2036,508,1071,29,1895,199,2412,1436,1001,179,1261,892,2365,2232,1941,1005,2552,1380,2270,569,79,786,2183,1330,1863,1864,2092,700,132,202,701,1010,612,111,33,1866,15,270,1608,1494,842,705,616,617,576,2000,1447,1207,951,752,162,1448,796,296,548,1745,846,2004,401,847,2481,2923,1503,314,2422,205,2191,2916,1953,2047,579,1612,91,2621,2101,519,1088,1707,2236,1812,212,1614,1813,1907,301,353,1024,550,1666,354,1216,2382,521,1617,1618,1816,760,1029,1218,2489,714,763,141,1094,1392,1393,1622,1911,1283,582,2491,1226,2158,2799,2735,856,1286,720,857,120,466,2297,2920,812,1672,2208,485,194,18,121,81,1716,2389,438,2163,722,2718,1104,1519,1292,1105,813,1038,2393,1234 -0.8039614683338043,0.6027831121744145,-0.3743938386878874,0.9027628846125711,0.704699791414857,0.17410512476192191,0.7382358716884349,-0.8941728675715074,-0.015336908887356353,1.5133178288044788,0.9990456262708737,-0.2519914877556342,0.24801958368154803,1.2776448956782354,0.9350551147231273,-0.21180894066884262,-0.3743938386878874,0.9027628846125711,-0.4575872142200032,-1.1742638113510904,0.2111917997668451,0.6027831121744145,0.02309828334687722,0.32091216739564127,0.1367560507410777,0.9350551147231273,-0.9398534966833773,-0.09305436959858496,1.1247147016520551,0.7382358716884349,-0.33327939055474815,-0.13234464502495924,0.3928095936133701,-1.0323962561974658,-1.8904581760074333,0.6709474376181863,-1.3199640839408484,3.513047173839545,0.8702695242261951,-1.1742638113510904,-1.5718746398609995,0.0612563185418274,0.0612563185418274,0.28459191556669194,-0.8941728675715074,0.28459191556669194,0.32091216739564127,1.0935808714347506,-0.4575872142200032,-0.6279701240574134,-0.4996758503153541,-1.222394988641525,0.6709474376181863,-0.2519914877556342,-1.3199640839408484,0.0612563185418274,-0.7152427522665485,0.2111917997668451,-0.1719280959561597,0.2111917997668451,0.49884576098804173,0.428393191730484,3.2128208825072786,-0.4158281796670899,0.6027831121744145,0.28459191556669194,-0.4575872142200032,2.0333215775625626,0.2111917997668451,0.17410512476192191,0.428393191730484,-0.9398534966833773,0.17410512476192191,-0.8488775839823314,1.2474172170623723,0.463737560425262,0.8046697182564764,0.2111917997668451,0.8046697182564764,0.1367560507410777,-1.1742638113510904,-0.2519914877556342,0.32091216739564127,1.0307485270519672,1.4261935465788533,-0.3743938386878874,0.6709474376181863,0.6709474376181863,0.6709474376181863,0.704699791414857,0.32091216739564127,0.2111917997668451,0.9671485853633185,-0.015336908887356353,2.3364949483641926,-0.4575872142200032,-0.05405313922784484,0.24801958368154803,0.24801958368154803,-0.1719280959561597,0.32091216739564127,0.5683656165997513,2.237423692928971,0.02309828334687722,0.463737560425262,0.32091216739564127,-0.4575872142200032,0.5337207971688037,0.17410512476192191,-0.5848621144923504,-0.4575872142200032,-0.015336908887356353,1.7387054861501252,0.8375726207273704,1.0935808714347506,2.237423692928971,0.5337207971688037,-0.4158281796670899,0.704699791414857,0.28459191556669194,3.0450375649426276,-0.29248013870191797,1.1864283685836194,-0.759418488288081,0.0612563185418274,0.32091216739564127,1.2776448956782354,0.17410512476192191,0.3928095936133701,-0.7152427522665485,-0.5848621144923504,-0.33327939055474815,0.32091216739564127,-0.9398534966833773,0.09914099907683403,-0.6279701240574134,0.6369761233848037,1.901497527876068,0.463737560425262,-0.5420991063561916,0.1367560507410777,-0.2519914877556342,-0.2519914877556342,-0.4575872142200032,0.5337207971688037,1.5133178288044788,1.1864283685836194,0.5337207971688037,0.32091216739564127,0.6027831121744145,1.655335720828877,2.959000560087587,-0.2519914877556342,3.994138285325319,1.0307485270519672,-0.05405313922784484,0.02309828334687722,0.428393191730484,0.5337207971688037,0.6027831121744145,0.6027831121744145,0.6369761233848037,-0.3743938386878874,0.0612563185418274,0.2111917997668451,0.35698364577547,0.49884576098804173,1.33757659471794,0.0612563185418274,0.463737560425262,0.9990456262708737,0.6709474376181863,-0.1719280959561597,0.428393191730484,-0.3743938386878874,0.8375726207273704,0.428393191730484,-0.8488775839823314,-3.1069065994161518,0.02309828334687722,0.9671485853633185,-0.759418488288081,1.1864283685836194,-0.5420991063561916,-2.589360161351481,-0.33327939055474815,-0.4158281796670899,0.6369761233848037,-0.05405313922784484,1.8207460887469624,-1.0323962561974658,-0.4575872142200032,0.704699791414857,0.28459191556669194,-0.13234464502495924,-0.5848621144923504,-0.21180894066884262,1.155663166669387,-0.05405313922784484,-0.21180894066884262,-0.29248013870191797,0.9990456262708737,0.9027628846125711,0.32091216739564127,0.6709474376181863,-0.09305436959858496,0.9027628846125711,0.2111917997668451,-0.7152427522665485,0.704699791414857,-0.05405313922784484,-0.05405313922784484,-0.21180894066884262,0.49884576098804173,0.32091216739564127,0.2111917997668451,-0.8488775839823314,0.5337207971688037,0.49884576098804173,1.455398437788666,0.28459191556669194,0.09914099907683403,0.09914099907683403,-0.05405313922784484,-0.29248013870191797,0.17410512476192191,0.6369761233848037,-0.8488775839823314,0.2111917997668451,-0.4996758503153541,-1.469700408349865,-1.2709592380232988,0.428393191730484,0.17410512476192191,0.5337207971688037,0.428393191730484,1.5705949318057502,0.7715583169098631,-0.6279701240574134,-2.714784907553634,0.463737560425262,-0.09305436959858496,-0.5420991063561916,0.7382358716884349,1.2170123744522818,3.7962488360202657,1.5705949318057502,1.901497527876068,-0.13234464502495924,-0.7152427522665485,0.8046697182564764,-0.4996758503153541,0.5337207971688037,-1.222394988641525,0.28459191556669194,0.02309828334687722,0.17410512476192191,0.28459191556669194,0.463737560425262,0.32091216739564127,-0.7152427522665485,0.2111917997668451 2937 Interleukin 1 family signaling 30 50 2.7483317667783416 0.0059899365240321 P49720,P45985,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P09429,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,Q9H3S7,P28070,Q06323,Q9UNM6,Q13200,P20618,P40763,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,501,876,811,549,149,165,539,578,415,50,840,919,686,560,834,201,198,326,327,477,762,105,890,767,745,735,598,362,253 149,1106,560,1353,1919,165,919,415,362,735,1183,926,1184,1418,876,105,326,327,686,598,1480,501,539,884,50,198,834,1431,1856,477,1374,1127,1259,1071,2444,2579,890,2744,745,1006,840,201,578,253,549,1460,762,1715,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,0.8046697182564764,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.6027831121744145,0.02309828334687722,0.704699791414857,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.28459191556669194,-0.8039614683338043,-0.9859257988083908,0.3928095936133701,-1.3199640839408484,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.0612563185418274,0.49884576098804173,-0.13234464502495924,0.463737560425262,0.49884576098804173 2937 SLC superfamily of solute carriers 8 37 2.7468263065435705 0.0060174993483215 Q70HW3,O43772,Q8IXU6,O95563,Q9Y6M7,Q9H2D1,P53985,Q6N075 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 294,4,11,262,148,188,161,30 2016,4,2066,2303,1237,262,2305,984,2353,2125,2306,1928,2509,161,1429,1795,2137,1334,30,2044,2556,294,11,1503,338,1564,1509,626,188,1669,1394,2734,1398,1965,2392,768,148 -0.4158281796670899,4.835200926172848,-0.4575872142200032,-0.6714285051358926,0.17410512476192191,1.0307485270519672,-0.6714285051358926,0.32091216739564127,-0.7152427522665485,-0.4996758503153541,-0.6714285051358926,-0.33327939055474815,-0.8941728675715074,1.33757659471794,0.0612563185418274,-0.21180894066884262,-0.4996758503153541,0.1367560507410777,3.0450375649426276,-0.4158281796670899,-0.9398534966833773,0.9990456262708737,4.318354335440558,0.02309828334687722,0.9350551147231273,-0.015336908887356353,0.02309828334687722,0.6027831121744145,1.2474172170623723,-0.09305436959858496,0.09914099907683403,-1.2709592380232988,0.09914099907683403,-0.33327939055474815,-0.7152427522665485,0.49884576098804173,1.4261935465788533 2937 Pyrimidine nucleotide metabolic process 7 18 2.74061220519231 0.0061324839099976 Q9H773,Q9BZX2,Q9NRF8,P04818,P17812,P34896,Q05682 Processes and pathways GO Biological process msigdb_gobp 1,436,138,445,447,328,59 445,1781,1682,681,447,1725,1591,496,776,1248,879,328,930,1858,59,436,1,138 0.7715583169098631,-0.21180894066884262,-0.13234464502495924,0.5337207971688037,0.7715583169098631,-0.1719280959561597,-0.05405313922784484,0.704699791414857,0.463737560425262,0.17410512476192191,0.3928095936133701,0.9350551147231273,0.35698364577547,-0.2519914877556342,2.1363911463999377,0.8046697182564764,5.8748316084197345,1.484439279959394 2937 Vesicle mediated transport 88 214 2.725657124321549 0.006417362409107 O00443,O15144,Q8WTV0,Q8IUR0,P20645,P09496,P48444,P49257,Q92538,P35579,P20339,P24390,Q16706,Q4KMP7,Q14108,Q9H0B6,P61923,O43617,O00203,P61201,Q99627,P52732,Q9NZZ3,Q15363,Q15436,O43237,Q9UQ16,Q8TD16,P84085,P62258,P60520,Q14203,Q8IYI6,Q92905,Q9BXS5,O60763,Q13885,P62993,P02786,Q9Y496,Q86X10,P07900,Q9UBW8,Q86SZ2,Q9UIQ6,Q9Y6G9,Q9BT78,Q9Y678,P59998,Q96A65,P31150,O94979,P53621,O60749,O75935,Q14671,Q14247,Q8TBA6,Q13409,Q01082,P50570,P04350,Q9NZ32,Q9P2W9,Q9UID3,Q14204,P11142,P18085,P27348,P32121,Q13561,Q12907,O15498,Q8N6T3,P62820,P61163,P31946,Q13813,Q9UJY4,Q07157,P33176,Q14C86,Q9BVK6,Q9UJW0,Q9UPT5,Q9Y4L1,Q00610,P63104 Processes and pathways Reactome Pathways msigdb_reactome 486,487,10,548,25,535,538,541,579,63,563,67,612,613,79,92,96,588,585,602,133,648,718,700,701,182,194,205,694,692,691,211,753,754,760,219,747,236,732,259,252,245,276,796,277,280,272,813,266,300,777,284,783,282,283,787,786,314,311,310,308,305,855,856,857,332,823,825,827,832,895,892,346,401,395,393,385,426,466,479,473,512,521,528,529,531,508,507 2119,1968,1041,2907,2801,585,1969,486,916,1522,1236,1831,1109,487,860,1970,346,182,2018,588,1471,1300,1634,282,219,1924,283,1775,1678,284,1302,1303,2815,1411,732,305,245,535,1837,823,2437,1178,1842,2354,825,1362,563,25,2079,67,827,2546,777,878,385,832,473,63,1188,992,882,1064,1985,2226,1787,538,541,993,1195,308,1597,2085,1598,1728,648,1196,1485,783,997,1599,1729,1486,2228,266,691,2230,2088,1542,2360,1067,393,602,96,1255,692,395,236,1546,507,2511,2638,694,508,310,2607,889,479,1074,2412,1436,1001,892,2365,1325,1326,2232,311,1941,895,2270,426,747,79,211,332,786,787,1330,2794,512,1864,1331,1554,700,701,1203,612,613,2142,1270,1271,1866,946,2648,1207,796,252,548,753,401,2146,1502,314,2482,205,10,2764,1953,579,2621,1453,958,754,300,1748,133,2106,2379,1347,1665,2380,272,1568,1153,521,1667,760,92,1219,2489,2339,1911,1758,968,1227,855,718,856,1286,276,857,277,528,466,1878,2297,1672,1575,1167,1916,529,194,1716,1104,1518,914,259,1294,531,1105,813,1038,280,1234 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2937 Modified amino acid binding 8 20 2.7253955326095 0.0064224497064691 P00374,Q8WTV0,P04818,Q9H7Z7,Q14108,P09429,O43813,Q99829 Functions GO Molecular function msigdb_gomf 103,10,445,141,79,415,112,482 112,1770,103,445,1413,2174,415,823,1783,1590,1190,503,79,10,1664,482,2243,141,723,2061 1.627243250148423,-0.21180894066884262,1.6832758718136789,0.7715583169098631,0.0612563185418274,-0.5420991063561916,0.8046697182564764,0.428393191730484,-0.21180894066884262,-0.05405313922784484,0.2111917997668451,0.704699791414857,1.901497527876068,4.351275402719301,-0.09305436959858496,0.7382358716884349,-0.5848621144923504,1.455398437788666,0.5337207971688037,-0.4158281796670899 2937 Fcgamma receptor fcgr dependent phagocytosis 9 25 2.724750468452417 0.0064350100826318 P07900,Q9NZQ3,P62993,P19174,Q9UQB8,P59998,Q96JJ3,P08238,P35579 Processes and pathways Reactome Pathways msigdb_reactome 245,142,236,234,18,266,434,306,63 1041,487,860,245,306,234,1364,828,1247,63,266,1254,2360,1067,236,2093,1698,1745,958,1505,434,142,18,2347,1294 0.28459191556669194,0.704699791414857,0.3928095936133701,1.0622595380909912,0.9671485853633185,1.0935808714347506,0.09914099907683403,0.428393191730484,0.17410512476192191,2.085115891068643,1.0307485270519672,0.17410512476192191,-0.7152427522665485,0.28459191556669194,1.0935808714347506,-0.4575872142200032,-0.13234464502495924,-0.1719280959561597,0.35698364577547,0.02309828334687722,0.8046697182564764,1.455398437788666,3.7962488360202657,-0.6714285051358926,0.17410512476192191 2937 L1cam interactions 12 36 2.7203780320898434 0.0065207322418698 Q9UQ16,P09496,P15311,Q13813,P50570,P35241,P26038,O14786,Q01082,Q15418,P04350,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 194,535,134,426,308,76,176,118,310,292,305,508 118,1678,1302,1411,305,2261,535,823,134,1478,176,828,1247,76,1846,308,1855,1599,1546,1731,508,310,1071,2365,426,747,2092,292,2093,1898,1748,580,1344,1568,1153,194 1.5705949318057502,-0.13234464502495924,0.1367560507410777,0.0612563185418274,0.9671485853633185,-0.6279701240574134,0.6709474376181863,0.428393191730484,1.484439279959394,0.02309828334687722,1.2776448956782354,0.428393191730484,0.17410512476192191,1.9281348523770536,-0.2519914877556342,0.9671485853633185,-0.2519914877556342,-0.05405313922784484,-0.015336908887356353,-0.1719280959561597,0.704699791414857,0.9671485853633185,0.28459191556669194,-0.7152427522665485,0.8046697182564764,0.49884576098804173,-0.4575872142200032,0.9990456262708737,-0.4575872142200032,-0.29248013870191797,-0.1719280959561597,0.6369761233848037,0.1367560507410777,-0.015336908887356353,0.24801958368154803,1.2170123744522818 2937 Mitotic g2 g2 m phases 47 83 2.710777205867801 0.0067125712776454 P07900,Q9BSJ2,P14635,P49720,P62140,P61163,P28066,Q9UL46,P06493,Q99460,O00231,Q9H6D7,P24941,O43242,O75935,P48556,Q92530,P49721,Q14997,Q13409,P08238,P04350,P35998,O00487,P17612,P55036,Q15008,P51665,Q14008,Q14204,P62258,Q14203,P28072,P28074,P62191,Q15154,Q13561,P28070,Q06323,Q9UNM6,Q96CW5,Q13885,O94927,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 245,403,873,884,394,393,876,811,263,549,149,164,775,165,283,539,578,50,840,311,306,305,686,560,824,834,201,198,697,332,692,211,326,327,477,897,895,105,890,767,376,747,592,745,735,362,253 149,1106,560,1353,1767,859,165,919,283,592,1679,305,2025,263,1057,245,306,873,824,362,735,775,1183,926,1184,1418,876,105,326,327,990,1060,686,1064,1480,539,884,50,1851,198,1484,834,1431,2230,393,1856,1255,394,477,1374,692,1127,1258,2511,1259,890,1602,745,311,895,1006,747,697,211,332,840,201,897,1010,578,376,253,549,403,1568,1153,164,2387,2932,811,2887,767,1628 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.21180894066884262,0.3928095936133701,1.3076973767692464,0.35698364577547,0.9990456262708737,0.6027831121744145,-0.13234464502495924,0.9671485853633185,-0.4158281796670899,1.0307485270519672,0.28459191556669194,1.0622595380909912,0.9671485853633185,0.3928095936133701,0.428393191730484,0.8702695242261951,0.49884576098804173,0.463737560425262,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.32091216739564127,0.28459191556669194,0.5337207971688037,0.28459191556669194,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,-0.2519914877556342,1.1864283685836194,0.02309828334687722,0.428393191730484,0.0612563185418274,-0.5848621144923504,0.8375726207273704,-0.2519914877556342,0.17410512476192191,0.8375726207273704,0.7382358716884349,0.09914099907683403,0.5337207971688037,0.24801958368154803,0.17410512476192191,-0.8941728675715074,0.17410512476192191,0.3928095936133701,-0.05405313922784484,0.49884576098804173,0.9671485853633185,0.3928095936133701,0.32091216739564127,0.49884576098804173,0.5337207971688037,1.155663166669387,0.9350551147231273,0.428393191730484,1.1864283685836194,0.3928095936133701,0.32091216739564127,0.6369761233848037,0.8702695242261951,1.0622595380909912,0.6709474376181863,0.8375726207273704,-0.015336908887356353,0.24801958368154803,1.33757659471794,-0.7152427522665485,-5.340644546223399,0.463737560425262,-2.0009314909515403,0.49884576098804173,-0.05405313922784484 2937 Clathrin coated vesicle 12 42 2.7067310167891985 0.0067949287590549 O00443,P20339,Q9UJY4,P50570,P09496,P42892,Q5VW38,Q14108,Q9BVK6,Q9UJU6,P20645,Q00610 Localization GO Cellular component msigdb_gocc 486,563,466,308,535,106,15,79,521,120,25,508 585,1969,486,1471,2802,1678,1411,732,535,1837,823,1178,563,25,106,993,308,1598,1124,1728,1599,2230,1542,1546,508,1941,79,1554,15,842,1748,521,760,1218,1030,1622,968,1285,120,466,1672,1105 0.6027831121744145,-0.3743938386878874,0.704699791414857,0.02309828334687722,-1.5205468840168608,-0.13234464502495924,0.0612563185418274,0.49884576098804173,0.6709474376181863,-0.2519914877556342,0.428393191730484,0.2111917997668451,0.6369761233848037,3.2128208825072786,1.6832758718136789,0.32091216739564127,0.9671485853633185,-0.05405313922784484,0.24801958368154803,-0.1719280959561597,-0.05405313922784484,-0.5848621144923504,-0.015336908887356353,-0.015336908887356353,0.704699791414857,-0.33327939055474815,1.901497527876068,-0.015336908887356353,3.994138285325319,0.428393191730484,-0.1719280959561597,0.704699791414857,0.49884576098804173,0.2111917997668451,0.32091216739564127,-0.05405313922784484,0.35698364577547,0.17410512476192191,1.5705949318057502,0.7715583169098631,-0.09305436959858496,0.28459191556669194 2937 Actin filament bundle organization 13 39 2.701084936575016 0.0069113685906874 P15311,Q08722,Q15942,Q13177,P35241,P35611,P42345,P16949,Q9UQB8,P35080,Q07157,O14786,Q05682 Processes and pathways GO Biological process msigdb_gobp 134,424,203,139,76,287,265,143,18,366,479,118,59 725,118,978,471,1680,2261,983,870,2806,1842,134,143,2026,1643,366,76,287,265,2759,1254,931,2511,59,479,424,139,1380,938,1897,203,2093,2040,755,1957,1348,1963,1399,18,1577 0.49884576098804173,1.5705949318057502,0.32091216739564127,0.7382358716884349,-0.13234464502495924,-0.6279701240574134,0.32091216739564127,0.3928095936133701,-1.5205468840168608,-0.2519914877556342,1.484439279959394,1.4261935465788533,-0.4158281796670899,-0.09305436959858496,0.8702695242261951,1.9281348523770536,0.9990456262708737,1.0307485270519672,-1.3694172456596465,0.17410512476192191,0.35698364577547,-0.8941728675715074,2.1363911463999377,0.7382358716884349,0.8046697182564764,1.455398437788666,0.09914099907683403,0.35698364577547,-0.29248013870191797,1.1864283685836194,-0.4575872142200032,-0.4158281796670899,0.49884576098804173,-0.33327939055474815,0.1367560507410777,-0.33327939055474815,0.09914099907683403,3.7962488360202657,-0.015336908887356353 2937 Regulation of neuron projection development 18 60 2.7003041737417863 0.0069276106592337 Q9UQ16,P78344,Q9H4M9,Q9Y639,Q9P265,Q13177,Q9NR77,Q9NZQ3,P08670,Q14108,Q9UQB8,Q02790,Q9UPN3,Q6SZW1,O14786,Q14444,Q9UJU6,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 194,68,340,408,242,139,13,142,414,79,18,509,485,87,118,428,120,61 118,1831,1921,2802,1114,414,2026,1364,777,1064,2084,645,1251,1067,931,68,1937,1071,509,889,1379,1199,139,1003,1605,79,938,428,1333,2512,2093,2447,1268,87,2046,1698,1142,706,1014,2485,1213,2829,1755,340,526,13,1757,2733,142,242,120,1761,2297,631,485,194,18,975,61,408 1.5705949318057502,-0.2519914877556342,-0.33327939055474815,-1.5205468840168608,0.24801958368154803,0.8046697182564764,-0.4158281796670899,0.09914099907683403,0.463737560425262,0.28459191556669194,-0.4575872142200032,0.5683656165997513,0.17410512476192191,0.28459191556669194,0.35698364577547,2.0333215775625626,-0.33327939055474815,0.28459191556669194,0.704699791414857,0.3928095936133701,0.09914099907683403,0.2111917997668451,1.455398437788666,0.32091216739564127,-0.05405313922784484,1.901497527876068,0.35698364577547,0.8046697182564764,0.1367560507410777,-0.8941728675715074,-0.4575872142200032,-0.8039614683338043,0.17410512476192191,1.8478045517497095,-0.4158281796670899,-0.13234464502495924,0.24801958368154803,0.5337207971688037,0.32091216739564127,-0.8488775839823314,0.2111917997668451,-1.623692476299974,-0.1719280959561597,0.9350551147231273,0.704699791414857,4.2518449635579465,-0.1719280959561597,-1.2709592380232988,1.455398437788666,1.0935808714347506,1.5705949318057502,-0.1719280959561597,-0.6279701240574134,0.6027831121744145,0.7382358716884349,1.2170123744522818,3.7962488360202657,0.35698364577547,2.1108177774831414,0.8375726207273704 2937 Selective autophagy 9 27 2.6971845933561305 0.0069928494571001 P07900,P21796,Q9NS69,Q9Y6G9,Q8N4H5,Q9UBN7,Q13409,P04350,O43237 Processes and pathways Reactome Pathways msigdb_reactome 245,99,7,280,60,80,311,305,182 182,1634,2720,2399,2501,305,245,414,823,1478,99,1934,2511,1731,311,747,332,1136,60,960,2378,1346,1568,1153,7,80,280 1.2474172170623723,-0.09305436959858496,-1.2709592380232988,-0.759418488288081,-0.8941728675715074,0.9671485853633185,1.0622595380909912,0.8046697182564764,0.428393191730484,0.02309828334687722,1.7110652769447776,-0.33327939055474815,-0.8941728675715074,-0.1719280959561597,0.9671485853633185,0.49884576098804173,0.9350551147231273,0.24801958368154803,2.1108177774831414,0.35698364577547,-0.7152427522665485,0.1367560507410777,-0.015336908887356353,0.24801958368154803,4.432627557673481,1.901497527876068,1.0307485270519672 2937 Axon 38 117 2.6929980216497493 0.0070812689199373 P46940,P07900,Q9Y639,P27816,P42858,Q99720,Q96A65,Q9Y5K6,P07197,Q9Y2T2,P50897,P35613,Q01082,P50570,Q05682,P08238,P04350,P20339,Q9UQ16,P78344,Q06787,Q14204,Q9UBN7,Q96A49,Q14203,Q6SZW1,P78310,P33176,O14617,Q9P265,Q99623,Q13614,Q02790,O14786,Q7Z406,Q9UPT5,Q9Y496,P27708 Localization GO Cellular component msigdb_gocc 131,245,408,497,144,23,300,440,157,438,49,420,310,308,59,306,305,563,194,68,566,332,80,212,211,87,478,473,469,242,377,110,509,118,119,529,259,496 585,469,118,1767,1883,2397,727,864,1583,2599,2024,1302,1115,305,2069,2791,157,245,306,823,2876,772,563,2026,2178,1181,2079,1119,496,497,2128,777,473,420,1686,1727,144,1064,1536,645,131,1251,308,49,1371,1789,1125,783,1318,1989,931,478,68,1129,1937,310,509,59,566,1074,2365,567,1002,895,110,2415,2773,938,211,332,786,1202,2092,2093,2611,2447,2040,2274,87,1698,119,706,753,1502,1811,2621,959,212,300,1506,1346,377,23,1030,2829,1755,1757,967,2246,855,1397,2343,242,807,1286,80,2160,2297,2887,529,194,2115,438,259,1294,440,408 0.6027831121744145,0.7382358716884349,1.5705949318057502,-0.21180894066884262,-0.29248013870191797,-0.759418488288081,0.49884576098804173,0.3928095936133701,-0.05405313922784484,-1.0323962561974658,-0.4158281796670899,0.1367560507410777,0.24801958368154803,0.9671485853633185,-0.4575872142200032,-1.469700408349865,1.33757659471794,1.0622595380909912,0.9671485853633185,0.428393191730484,-1.9454153738987696,0.463737560425262,0.6369761233848037,-0.4158281796670899,-0.5420991063561916,0.2111917997668451,-0.4575872142200032,0.24801958368154803,0.704699791414857,0.704699791414857,-0.4996758503153541,0.463737560425262,0.7382358716884349,0.8046697182564764,-0.13234464502495924,-0.1719280959561597,1.4261935465788533,0.28459191556669194,-0.015336908887356353,0.5683656165997513,1.5133178288044788,0.17410512476192191,0.9671485853633185,2.3364949483641926,0.09914099907683403,-0.21180894066884262,0.24801958368154803,0.463737560425262,0.1367560507410777,-0.3743938386878874,0.35698364577547,0.7382358716884349,2.0333215775625626,0.24801958368154803,-0.33327939055474815,0.9671485853633185,0.704699791414857,2.1363911463999377,0.6369761233848037,0.28459191556669194,-0.7152427522665485,0.6369761233848037,0.32091216739564127,0.3928095936133701,1.655335720828877,-0.759418488288081,-1.4193266439978673,0.35698364577547,1.155663166669387,0.9350551147231273,0.463737560425262,0.2111917997668451,-0.4575872142200032,-0.4575872142200032,-1.0323962561974658,-0.8039614683338043,-0.4158281796670899,-0.6279701240574134,1.8478045517497095,-0.13234464502495924,1.5705949318057502,0.5337207971688037,0.49884576098804173,0.02309828334687722,-0.21180894066884262,-1.0323962561974658,0.35698364577547,1.155663166669387,0.9990456262708737,0.02309828334687722,0.1367560507410777,0.8702695242261951,3.434730873938129,0.32091216739564127,-1.623692476299974,-0.1719280959561597,-0.1719280959561597,0.35698364577547,-0.5848621144923504,0.428393191730484,0.09914099907683403,-0.6714285051358926,1.0935808714347506,0.463737560425262,0.17410512476192191,1.901497527876068,-0.4996758503153541,-0.6279701240574134,-2.0009314909515403,0.704699791414857,1.2170123744522818,-0.4575872142200032,0.8046697182564764,1.0622595380909912,0.17410512476192191,0.8046697182564764,0.8375726207273704 2937 Negative regulation of cell projection organization 10 26 2.682229404386796 0.0073133290119478 Q9UQ16,Q9P265,Q9NR77,P08670,P35080,O14786,Q02790,P50570,Q9NQC3,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 194,242,13,414,366,118,509,308,526,61 118,1831,1114,414,2026,497,777,366,1064,1787,1195,308,931,1937,509,889,938,1142,1014,2485,526,13,242,1761,194,61 1.5705949318057502,-0.2519914877556342,0.24801958368154803,0.8046697182564764,-0.4158281796670899,0.704699791414857,0.463737560425262,0.8702695242261951,0.28459191556669194,-0.21180894066884262,0.2111917997668451,0.9671485853633185,0.35698364577547,-0.33327939055474815,0.704699791414857,0.3928095936133701,0.35698364577547,0.24801958368154803,0.32091216739564127,-0.8488775839823314,0.704699791414857,4.2518449635579465,1.0935808714347506,-0.1719280959561597,1.2170123744522818,2.1108177774831414 2937 Anion transport 14 65 2.6782690356320606 0.0074003750513895 P14174,Q96NB2,P30536,P21796,Q9UHG3,P08183,Q9Y4C2,O95563,Q9Y6M7,P07602,O95342,Q9H2D1,P53985,Q6N075 Processes and pathways GO Biological process msigdb_gobp 122,338,160,99,38,8,319,262,148,151,22,188,161,30 1352,1108,2019,2066,2021,2303,866,22,262,1473,2305,2261,151,8,984,2739,2353,2125,2306,122,2178,99,1308,160,1928,329,1125,1372,2509,161,2227,1429,2266,1795,2137,424,1002,510,1134,789,1864,1334,1203,2448,30,2044,2556,1503,338,1907,1564,1509,188,1669,1394,1622,2734,1398,38,2593,1965,2250,319,2392,148 0.09914099907683403,0.24801958368154803,-0.4158281796670899,-0.4575872142200032,-0.4158281796670899,-0.6714285051358926,0.3928095936133701,3.513047173839545,1.0307485270519672,0.02309828334687722,-0.6714285051358926,-0.6279701240574134,1.3968228224013606,4.383977831042348,0.32091216739564127,-1.3199640839408484,-0.7152427522665485,-0.4996758503153541,-0.6714285051358926,1.5420358124097335,-0.5420991063561916,1.7110652769447776,0.1367560507410777,1.33757659471794,-0.33327939055474815,0.9350551147231273,0.24801958368154803,0.09914099907683403,-0.8941728675715074,1.33757659471794,-0.5848621144923504,0.0612563185418274,-0.6279701240574134,-0.21180894066884262,-0.4996758503153541,0.8046697182564764,0.32091216739564127,0.704699791414857,0.24801958368154803,0.463737560425262,-0.2519914877556342,0.1367560507410777,0.2111917997668451,-0.8039614683338043,3.0450375649426276,-0.4158281796670899,-0.9398534966833773,0.02309828334687722,0.9350551147231273,-0.29248013870191797,-0.015336908887356353,0.02309828334687722,1.2474172170623723,-0.09305436959858496,0.09914099907683403,-0.05405313922784484,-1.2709592380232988,0.09914099907683403,2.691723830472613,-0.9859257988083908,-0.33327939055474815,-0.5848621144923504,0.9671485853633185,-0.7152427522665485,1.4261935465788533 2937 Regulation of mrna stability by proteins that bind au rich elements 36 62 2.675511467923103 0.0074615320433162 P49720,P28066,Q9UL46,O14980,P31946,Q99460,O00231,P11940,Q01105,Q92973,O43242,Q04637,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,Q9Y2L1,P51665,P11142,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P39687,P17980,Q99436,P63104 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,859,385,549,149,770,28,432,165,171,539,578,50,840,919,686,560,834,201,344,198,823,326,327,477,105,890,767,745,735,247,362,253,507 149,1106,560,1353,859,165,919,2304,823,770,362,735,1183,926,1184,1418,876,105,326,327,385,1422,686,247,1480,539,884,50,198,834,1431,1856,477,1374,1127,507,28,171,2411,890,745,1799,1862,840,201,2038,2667,1011,2513,578,1905,432,2587,253,549,2244,2292,2109,811,767,344,1404 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,0.3928095936133701,1.3076973767692464,0.35698364577547,-0.6714285051358926,0.428393191730484,0.463737560425262,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.8375726207273704,0.0612563185418274,0.5337207971688037,1.0622595380909912,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.704699791414857,3.0663191302423836,1.3076973767692464,-0.759418488288081,0.3928095936133701,0.49884576098804173,-0.21180894066884262,-0.2519914877556342,0.428393191730484,1.1864283685836194,-0.4158281796670899,-1.1265583700744997,0.32091216739564127,-0.8941728675715074,0.6369761233848037,-0.29248013870191797,0.8046697182564764,-0.9859257988083908,1.0622595380909912,0.6709474376181863,-0.5848621144923504,-0.6279701240574134,-0.4575872142200032,0.463737560425262,0.49884576098804173,0.9350551147231273,0.09914099907683403 2937 Cellular protein catabolic process 100 222 2.671724634195183 0.0075462545340447 P48729,P62081,Q99460,Q9Y5A7,Q9UHG3,P48556,Q92530,P50897,P49721,Q96QK1,Q15370,O00487,Q06787,P35241,Q9UBN7,Q9H7D7,P62829,P28070,O75844,P46379,Q16763,Q8WUM4,O14773,P15311,Q9Y4E8,Q14139,O00231,O43242,Q8IWQ3,P26038,O60826,Q9NZZ3,Q9UPU5,Q8N511,P35998,Q15008,P36776,P51665,Q13620,P60520,Q7Z6Z7,P54727,Q9H2J4,Q9H3S7,Q9UNM6,Q13200,P20618,Q16740,O75150,O95376,Q99436,Q96K76,P07900,Q6ZXV5,Q5VYK3,Q9UJX3,Q9UL46,Q5VTR2,P48506,P24941,Q8N163,Q14997,P08238,Q93034,Q92990,P17612,P55036,O60524,O95714,P0DMV9,P28072,P28074,P30260,P32121,Q06323,Q9UNN5,Q9GZP4,Q9ULT8,P17980,O15372,Q8NBM4,P49720,P28066,O14980,Q93008,Q86UK7,Q99496,Q9Y5K6,Q13617,O94822,Q9Y3I1,Q5T4S7,O75832,P22314,Q9H871,P61086,P62191,Q16186,Q9NYU2,Q13546 Processes and pathways GO Biological process msigdb_gobp 502,505,549,559,38,539,578,49,50,581,572,560,566,76,80,627,607,105,102,114,126,661,129,134,673,655,149,165,706,176,175,718,191,186,686,201,687,198,696,691,752,224,761,762,767,745,735,237,727,731,253,798,245,794,270,810,811,269,779,775,845,840,306,851,335,824,834,818,820,822,326,327,829,832,890,912,905,910,362,862,402,884,876,859,959,952,962,440,425,413,975,944,919,924,463,452,477,515,527,510 1764,2120,149,560,129,1353,1767,2122,859,1581,862,165,2213,818,175,727,919,102,1835,2257,1636,413,1586,2219,2068,1357,731,820,1115,1053,981,1413,245,306,822,1529,1887,1842,1242,134,824,1180,362,1478,735,924,2079,775,1183,926,1184,1418,176,2546,2128,876,105,326,327,829,832,2130,76,686,687,1932,1480,1481,114,1189,779,539,502,884,50,1251,49,2085,1124,198,2686,1484,997,998,224,834,1934,2882,691,1431,452,1856,505,477,1374,1127,607,1545,1259,1793,1068,890,566,1199,745,1550,935,1604,510,1006,425,1380,1007,696,655,1551,2140,1606,840,201,2184,1738,572,1441,1654,515,1865,237,126,2417,944,1947,269,270,1999,794,1384,1273,1949,752,1950,952,1274,2372,706,2584,845,1085,186,402,1702,2521,2189,2916,661,2764,578,2148,1212,1904,335,959,1388,851,1561,2745,2333,2283,798,1021,1151,581,2732,1345,253,549,962,1346,1347,2380,2009,1819,905,1460,1571,1280,761,762,627,463,2012,527,1227,2205,1825,718,2294,80,38,2388,810,1760,1574,1761,811,910,2748,1575,1102,767,912,1916,191,1403,975,673,1762,559,1233,440,1296,2118 -0.21180894066884262,-0.4996758503153541,1.3968228224013606,0.6369761233848037,1.5133178288044788,0.09914099907683403,-0.21180894066884262,-0.4996758503153541,0.3928095936133701,-0.05405313922784484,0.3928095936133701,1.3076973767692464,-0.5848621144923504,0.428393191730484,1.2776448956782354,0.49884576098804173,0.35698364577547,1.6832758718136789,-0.2519914877556342,-0.6279701240574134,-0.09305436959858496,0.8046697182564764,-0.05405313922784484,-0.5848621144923504,-0.4575872142200032,0.09914099907683403,0.49884576098804173,0.428393191730484,0.24801958368154803,0.28459191556669194,0.32091216739564127,0.0612563185418274,1.0622595380909912,0.9671485853633185,0.428393191730484,-0.015336908887356353,-0.29248013870191797,-0.2519914877556342,0.17410512476192191,1.484439279959394,0.428393191730484,0.2111917997668451,0.8702695242261951,0.02309828334687722,0.49884576098804173,0.35698364577547,-0.4575872142200032,0.463737560425262,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,1.2776448956782354,-0.9398534966833773,-0.4996758503153541,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.428393191730484,0.428393191730484,-0.4996758503153541,1.9281348523770536,0.5337207971688037,0.5337207971688037,-0.33327939055474815,0.02309828334687722,0.02309828334687722,1.627243250148423,0.2111917997668451,0.463737560425262,0.6709474376181863,0.704699791414857,0.3928095936133701,2.237423692928971,0.17410512476192191,2.3364949483641926,-0.4575872142200032,0.24801958368154803,1.1864283685836194,-1.1742638113510904,0.02309828334687722,0.32091216739564127,0.32091216739564127,1.1247147016520551,0.428393191730484,-0.33327939055474815,-2.0009314909515403,0.5337207971688037,0.0612563185418274,0.7715583169098631,-0.2519914877556342,0.704699791414857,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.6027831121744145,-0.015336908887356353,0.17410512476192191,-0.21180894066884262,0.28459191556669194,0.3928095936133701,0.6369761233848037,0.2111917997668451,0.49884576098804173,-0.015336908887356353,0.35698364577547,-0.05405313922784484,0.704699791414857,0.32091216739564127,0.8046697182564764,0.09914099907683403,0.32091216739564127,0.5337207971688037,0.5683656165997513,-0.015336908887356353,-0.4996758503153541,-0.05405313922784484,0.428393191730484,1.1864283685836194,-0.5420991063561916,-0.1719280959561597,0.6369761233848037,0.0612563185418274,-0.09305436959858496,0.704699791414857,-0.2519914877556342,1.0935808714347506,1.5420358124097335,-0.759418488288081,0.35698364577547,-0.33327939055474815,1.0307485270519672,1.0307485270519672,-0.3743938386878874,0.463737560425262,0.09914099907683403,0.17410512476192191,-0.33327939055474815,0.49884576098804173,-0.33327939055474815,0.35698364577547,0.17410512476192191,-0.7152427522665485,0.5337207971688037,-0.9859257988083908,0.428393191730484,0.28459191556669194,1.2474172170623723,0.8375726207273704,-0.13234464502495924,-0.8941728675715074,-0.5420991063561916,-2.589360161351481,0.5683656165997513,-1.3694172456596465,0.6369761233848037,-0.4996758503153541,0.2111917997668451,-0.29248013870191797,0.9350551147231273,0.35698364577547,0.09914099907683403,0.428393191730484,-0.015336908887356353,-1.3199640839408484,-0.6714285051358926,-0.6279701240574134,0.463737560425262,0.32091216739564127,0.24801958368154803,0.6369761233848037,-1.2709592380232988,0.1367560507410777,1.0622595380909912,0.6709474376181863,0.35698364577547,0.1367560507410777,0.1367560507410777,-0.7152427522665485,-0.3743938386878874,-0.21180894066884262,0.3928095936133701,0.0612563185418274,-0.015336908887356353,0.17410512476192191,0.49884576098804173,0.49884576098804173,0.6027831121744145,0.7715583169098631,-0.3743938386878874,0.704699791414857,0.2111917997668451,-0.5420991063561916,-0.21180894066884262,0.5337207971688037,-0.6279701240574134,1.901497527876068,2.691723830472613,-0.7152427522665485,0.463737560425262,-0.1719280959561597,-0.015336908887356353,-0.1719280959561597,0.463737560425262,0.3928095936133701,-1.3199640839408484,-0.015336908887356353,0.28459191556669194,0.49884576098804173,0.3928095936133701,-0.29248013870191797,1.2474172170623723,0.09914099907683403,0.35698364577547,0.5683656165997513,-0.1719280959561597,0.6709474376181863,0.2111917997668451,0.8046697182564764,0.17410512476192191,-0.4575872142200032 2937 Clathrin mediated endocytosis 25 48 2.670872865134809 0.0075654295036484 O00443,O15144,Q8N6T3,Q9UBW8,Q99627,P42566,Q9BT78,P59998,Q92747,P20645,P09496,Q14247,P50570,P20339,Q9UQ16,Q14108,P11142,P32121,Q92905,Q14C86,P62993,P61201,P02786,O15145,Q00610 Processes and pathways Reactome Pathways msigdb_reactome 486,487,401,276,133,882,272,266,958,25,535,786,308,563,194,79,823,832,754,512,236,602,732,860,508 1969,486,1831,487,860,1678,1411,732,535,1837,823,1178,563,25,2079,832,882,308,1597,1728,1599,266,2360,1067,602,236,1546,508,1326,1941,79,786,512,2648,401,958,754,1748,133,1665,272,968,276,1878,1167,1916,194,1105 -0.3743938386878874,0.704699791414857,-0.2519914877556342,0.704699791414857,0.3928095936133701,-0.13234464502495924,0.0612563185418274,0.49884576098804173,0.6709474376181863,-0.2519914877556342,0.428393191730484,0.2111917997668451,0.6369761233848037,3.2128208825072786,-0.4575872142200032,0.428393191730484,0.3928095936133701,0.9671485853633185,-0.05405313922784484,-0.1719280959561597,-0.05405313922784484,1.0307485270519672,-0.7152427522665485,0.28459191556669194,0.6027831121744145,1.0935808714347506,-0.015336908887356353,0.704699791414857,0.1367560507410777,-0.33327939055474815,1.901497527876068,0.463737560425262,0.704699791414857,-1.0792715109109947,0.8375726207273704,0.35698364577547,0.49884576098804173,-0.1719280959561597,1.5133178288044788,-0.09305436959858496,1.0307485270519672,0.35698364577547,1.0307485270519672,-0.2519914877556342,0.24801958368154803,-0.29248013870191797,1.2170123744522818,0.28459191556669194 2937 Negative regulation of cytoskeleton organization 16 42 2.6708235876397373 0.0075665401709543 O75122,Q13813,Q13177,P35241,P35611,Q9UBN7,P16949,P53384,Q92974,Q9NUQ9,P35080,Q01082,Q07157,P04350,Q13045,Q9BTW9 Processes and pathways GO Biological process msigdb_gobp 471,426,139,76,287,80,143,331,519,128,366,310,479,305,226,163 816,471,1114,305,1976,983,143,1182,1309,366,76,287,2356,645,2226,1787,1196,331,1318,601,2511,310,509,479,1379,226,139,2318,426,1010,1706,519,1750,853,1348,163,128,1963,80,1100,1399,2887 0.428393191730484,0.7382358716884349,0.24801958368154803,0.9671485853633185,-0.3743938386878874,0.32091216739564127,1.4261935465788533,0.2111917997668451,0.1367560507410777,0.8702695242261951,1.9281348523770536,0.9990456262708737,-0.7152427522665485,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,0.2111917997668451,0.9350551147231273,0.1367560507410777,0.6027831121744145,-0.8941728675715074,0.9671485853633185,0.704699791414857,0.7382358716884349,0.09914099907683403,1.1247147016520551,1.455398437788666,-0.6714285051358926,0.8046697182564764,0.32091216739564127,-0.13234464502495924,0.704699791414857,-0.1719280959561597,0.428393191730484,0.1367560507410777,1.33757659471794,1.5420358124097335,-0.33327939055474815,1.901497527876068,0.28459191556669194,0.09914099907683403,-2.0009314909515403 2937 Translation regulator activity 36 79 2.6692537923116944 0.0076019984404984 Q9Y450,P26641,Q9UI10,O00178,O75821,P11940,Q8NE71,P20042,P55884,Q04637,Q14152,Q6PKG0,Q92616,P55010,Q14011,P60228,O60841,P57772,P63241,P78344,Q06787,Q9Y262,P04818,P34896,Q92905,Q15056,P05198,Q13144,P00374,Q9BY44,O75822,P41214,P62495,P35268,P23588,P13639 Functions GO Molecular function msigdb_gomf 407,642,809,260,153,770,299,773,784,171,180,575,315,421,56,564,303,309,836,68,566,467,445,328,754,227,594,893,103,904,729,369,606,367,364,872 260,1521,2014,1042,862,1675,1045,303,153,729,103,445,594,1778,770,872,1978,1532,773,364,989,642,1419,1185,328,1983,367,1786,369,2224,2225,1482,2441,1192,994,1371,1789,421,784,2826,309,564,1066,1936,606,836,68,1377,171,1073,566,893,1437,56,180,2037,939,1079,227,1946,575,1140,1698,1658,1208,299,315,2195,754,2104,904,1874,1032,1397,1877,809,1230,467,407 1.0307485270519672,-0.015336908887356353,-0.4158281796670899,0.28459191556669194,0.3928095936133701,-0.13234464502495924,0.28459191556669194,0.9671485853633185,1.3672844525092513,0.49884576098804173,1.6832758718136789,0.7715583169098631,0.6027831121744145,-0.21180894066884262,0.463737560425262,0.3928095936133701,-0.3743938386878874,-0.015336908887356353,0.463737560425262,0.8702695242261951,0.32091216739564127,0.5683656165997513,0.0612563185418274,0.2111917997668451,0.9350551147231273,-0.3743938386878874,0.8702695242261951,-0.21180894066884262,0.8702695242261951,-0.5848621144923504,-0.5848621144923504,0.02309828334687722,-0.8039614683338043,0.2111917997668451,0.32091216739564127,0.09914099907683403,-0.21180894066884262,0.8046697182564764,0.463737560425262,-1.623692476299974,0.9671485853633185,0.6369761233848037,0.28459191556669194,-0.33327939055474815,0.6027831121744145,0.428393191730484,2.0333215775625626,0.09914099907683403,1.3076973767692464,0.28459191556669194,0.6369761233848037,0.3928095936133701,0.0612563185418274,2.161837222901003,1.2776448956782354,-0.4158281796670899,0.35698364577547,0.28459191556669194,1.1247147016520551,-0.33327939055474815,0.6369761233848037,0.24801958368154803,-0.13234464502495924,-0.09305436959858496,0.2111917997668451,0.9990456262708737,0.9671485853633185,-0.5420991063561916,0.49884576098804173,-0.4575872142200032,0.3928095936133701,-0.2519914877556342,0.32091216739564127,0.09914099907683403,-0.2519914877556342,0.463737560425262,0.2111917997668451,0.7715583169098631,0.8375726207273704 2937 Supramolecular polymer 50 190 2.6689130386862474 0.0076097149740985 P46940,Q9BSJ2,P15311,P27816,Q14019,Q9Y6G9,Q9NZQ3,P16949,Q9UQB8,P06493,Q9H6D7,Q9BTW9,Q9Y5K6,P07197,Q14152,P08670,Q13409,Q01082,P50570,Q05682,P04350,P35579,O43237,Q9UQ16,Q9HC35,Q14204,Q9UBN7,P50402,Q14203,Q9UPN3,Q6SZW1,P18206,Q9H0B6,P33176,Q96EY1,O75122,O00429,Q15555,Q9Y496,Q9UJW0,Q96CW5,Q53GG5,Q92974,P35580,Q02790,O14786,Q7Z406,Q9UJU6,Q9Y266,Q00610 Localization GO Cellular component msigdb_gocc 131,403,134,497,140,280,142,143,18,263,164,163,440,157,180,414,311,310,308,59,305,63,182,194,341,332,80,330,211,485,87,209,92,473,352,471,345,348,259,528,376,516,519,113,509,118,119,120,121,508 1968,725,1041,345,118,1767,816,182,2018,589,863,726,978,2169,1883,471,728,1772,2171,592,1302,1115,1528,2220,980,1836,1473,305,263,2173,2070,157,1057,414,2353,870,771,2806,2075,134,1179,143,734,209,1307,2026,1182,497,1309,1845,473,2130,63,113,2308,2682,1846,1367,1313,1064,645,131,1787,1250,600,502,541,1191,330,308,1426,1252,1371,648,1484,2826,742,1431,1257,2511,2136,1260,1937,508,1796,310,2607,509,933,59,1074,2412,543,1379,2365,1604,311,895,1380,747,697,140,180,938,211,332,786,1552,1132,1897,2794,1863,940,2184,1202,348,1010,1267,2851,2668,2093,1137,1898,2611,2447,943,516,1272,1494,87,2046,119,1807,2275,1950,2763,2923,2764,1706,1811,2194,1453,519,755,376,1616,352,1213,2283,1152,1022,2106,1456,1348,403,163,1568,1153,1667,92,2290,164,341,1757,2387,142,718,1285,805,80,1400,1516,120,528,2594,2887,1672,1102,485,194,18,121,1470,2347,259,1294,440,1520,1763,280 -0.3743938386878874,0.49884576098804173,0.28459191556669194,0.9027628846125711,1.5705949318057502,-0.21180894066884262,0.428393191730484,1.2474172170623723,-0.4158281796670899,0.6027831121744145,0.3928095936133701,0.49884576098804173,0.32091216739564127,-0.5420991063561916,-0.29248013870191797,0.7382358716884349,0.49884576098804173,-0.21180894066884262,-0.5420991063561916,0.6027831121744145,0.1367560507410777,0.24801958368154803,-0.015336908887356353,-0.5848621144923504,0.32091216739564127,-0.2519914877556342,0.02309828334687722,0.9671485853633185,1.0307485270519672,-0.5420991063561916,-0.4575872142200032,1.33757659471794,0.28459191556669194,0.8046697182564764,-0.7152427522665485,0.3928095936133701,0.463737560425262,-1.5205468840168608,-0.4575872142200032,1.484439279959394,0.2111917997668451,1.4261935465788533,0.49884576098804173,1.155663166669387,0.1367560507410777,-0.4158281796670899,0.2111917997668451,0.704699791414857,0.1367560507410777,-0.2519914877556342,0.7382358716884349,-0.4996758503153541,2.085115891068643,1.627243250148423,-0.6714285051358926,-1.1742638113510904,-0.2519914877556342,0.09914099907683403,0.1367560507410777,0.28459191556669194,0.5683656165997513,1.5133178288044788,-0.21180894066884262,0.17410512476192191,0.6027831121744145,0.704699791414857,0.6709474376181863,0.2111917997668451,0.9350551147231273,0.9671485853633185,0.0612563185418274,0.17410512476192191,0.09914099907683403,0.5683656165997513,0.02309828334687722,-1.623692476299974,0.49884576098804173,0.0612563185418274,0.17410512476192191,-0.8941728675715074,-0.4996758503153541,0.17410512476192191,-0.33327939055474815,0.704699791414857,-0.21180894066884262,0.9671485853633185,-1.0323962561974658,0.704699791414857,0.35698364577547,2.1363911463999377,0.28459191556669194,-0.759418488288081,0.6709474376181863,0.09914099907683403,-0.7152427522665485,-0.05405313922784484,0.9671485853633185,0.3928095936133701,0.09914099907683403,0.49884576098804173,0.5337207971688037,1.455398437788666,1.2776448956782354,0.35698364577547,1.155663166669387,0.9350551147231273,0.463737560425262,-0.015336908887356353,0.24801958368154803,-0.29248013870191797,-1.469700408349865,-0.2519914877556342,0.35698364577547,-0.5420991063561916,0.2111917997668451,0.9027628846125711,0.32091216739564127,0.17410512476192191,-1.7288348009106087,-1.1265583700744997,-0.4575872142200032,0.24801958368154803,-0.29248013870191797,-1.0323962561974658,-0.8039614683338043,0.35698364577547,0.704699791414857,0.17410512476192191,0.02309828334687722,1.8478045517497095,-0.4158281796670899,1.5705949318057502,-0.21180894066884262,-0.6279701240574134,-0.33327939055474815,-1.3694172456596465,-3.1069065994161518,-1.3694172456596465,-0.13234464502495924,-0.21180894066884262,-0.5420991063561916,0.0612563185418274,0.704699791414857,0.49884576098804173,0.8702695242261951,-0.05405313922784484,0.9027628846125711,0.2111917997668451,-0.6279701240574134,0.24801958368154803,0.32091216739564127,-0.4575872142200032,0.0612563185418274,0.1367560507410777,0.8375726207273704,1.33757659471794,-0.015336908887356353,0.24801958368154803,-0.09305436959858496,1.8207460887469624,-0.6279701240574134,1.33757659471794,0.9350551147231273,-0.1719280959561597,-0.7152427522665485,1.455398437788666,0.5337207971688037,0.17410512476192191,0.463737560425262,1.901497527876068,0.09914099907683403,0.02309828334687722,1.5705949318057502,0.704699791414857,-0.9859257988083908,-2.0009314909515403,-0.09305436959858496,0.28459191556669194,0.7382358716884349,1.2170123744522818,3.7962488360202657,1.5705949318057502,0.0612563185418274,-0.6714285051358926,1.0622595380909912,0.17410512476192191,0.8046697182564764,0.02309828334687722,-0.1719280959561597,1.0307485270519672 2937 Epithelial cell development 14 33 2.6666832643449365 0.0076603828497319 P46940,Q15382,P15311,P62820,P35241,P35611,P04818,P49327,P08670,P26038,Q9NQ88,P18206,Q07157,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 131,132,134,395,76,287,445,503,414,176,525,209,479,61 1919,2542,1772,445,414,2126,134,209,1783,176,76,287,1647,131,503,1251,1598,1854,886,395,1000,1895,479,1202,132,614,1811,2840,525,1963,2389,1518,61 -0.33327939055474815,-0.9398534966833773,-0.21180894066884262,0.7715583169098631,0.8046697182564764,-0.4996758503153541,1.484439279959394,1.155663166669387,-0.21180894066884262,1.2776448956782354,1.9281348523770536,0.9990456262708737,-0.09305436959858496,1.5133178288044788,0.704699791414857,0.17410512476192191,-0.05405313922784484,-0.2519914877556342,0.3928095936133701,0.8375726207273704,0.32091216739564127,-0.29248013870191797,0.7382358716884349,0.2111917997668451,1.5133178288044788,0.6027831121744145,-0.21180894066884262,-1.6760094336606017,0.704699791414857,-0.33327939055474815,-0.7152427522665485,0.02309828334687722,2.1108177774831414 2937 Regulation of epithelial cell migration 15 37 2.665054092388278 0.0076975940046697 P09601,O75122,Q15555,P42785,Q8WTV0,P42345,Q9UBN7,P09429,P06576,P06744,P19174,P35080,Q9UPN3,O14786,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 34,471,348,6,10,265,80,415,196,324,234,366,485,118,526 486,118,471,2814,1114,1473,196,324,983,415,34,2075,772,234,2178,2080,2546,366,265,6,1852,742,931,1731,1077,1861,348,1011,10,2796,762,2840,526,1963,80,2594,485 0.704699791414857,1.5705949318057502,0.7382358716884349,-1.5718746398609995,0.24801958368154803,0.02309828334687722,1.1864283685836194,0.9350551147231273,0.32091216739564127,0.8046697182564764,2.871469999732692,-0.4575872142200032,0.463737560425262,1.0935808714347506,-0.5420991063561916,-0.4575872142200032,-0.9398534966833773,0.8702695242261951,1.0307485270519672,4.496753993926139,-0.2519914877556342,0.49884576098804173,0.35698364577547,-0.1719280959561597,0.28459191556669194,-0.2519914877556342,0.9027628846125711,0.32091216739564127,4.351275402719301,-1.469700408349865,0.49884576098804173,-1.6760094336606017,0.704699791414857,-0.33327939055474815,1.901497527876068,-0.9859257988083908,0.7382358716884349 2937 Signaling by the b cell receptor bcr 27 45 2.6409744864275244 0.008266794451244 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P62993,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,236,362,253 149,1106,560,1353,1919,165,919,2502,2791,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1257,236,1259,2444,890,745,1006,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,-0.8941728675715074,-1.469700408349865,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,1.0935808714347506,0.17410512476192191,-0.8039614683338043,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Uch proteinases 29 46 2.6401754125865047 0.0082863125881798 P49720,Q9Y4E8,P28066,Q9UL46,Q99460,O00231,Q99496,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q16186,Q9UNM6,Q06323,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,673,876,811,549,149,962,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,515,767,890,745,735,362,253 149,1106,560,1353,1581,165,919,2572,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,1853,198,834,1431,1856,477,1374,1127,890,745,840,201,515,2869,578,253,549,962,811,767,2628,673,1233 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.05405313922784484,1.3076973767692464,0.35698364577547,-0.9859257988083908,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,-0.2519914877556342,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.3928095936133701,0.49884576098804173,0.428393191730484,1.1864283685836194,0.704699791414857,-1.8360492193607452,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.35698364577547,0.463737560425262,0.49884576098804173,-1.0323962561974658,0.5683656165997513,0.2111917997668451 2937 Er to golgi anterograde transport 34 68 2.6253110237742576 0.0086569849103741 Q8N6T3,Q86SZ2,P62820,Q9Y6G9,P61163,Q9Y678,Q8IUR0,O94979,Q13813,P53621,O75935,P48444,P49257,Q92538,Q13409,Q01082,Q15363,Q15436,P04350,Q9NZ32,O43237,P24390,Q14204,P84085,P18085,Q14203,Q13561,P61923,O60763,O15498,O43617,Q13885,Q9BVK6,Q9UJW0 Processes and pathways Reactome Pathways msigdb_reactome 401,796,395,280,393,813,548,284,426,783,283,538,541,579,311,310,700,701,305,855,182,67,332,694,825,211,895,96,219,346,588,747,521,528 1522,1236,1109,346,182,588,219,1924,283,284,1303,305,825,67,1188,1985,2226,1787,538,541,993,1196,1485,783,997,1729,1486,2228,393,96,395,2511,694,310,2412,892,2365,2232,311,895,426,747,211,332,1330,700,701,2142,1270,796,548,401,1953,579,2379,1568,1153,521,2339,855,1286,528,1716,1104,813,1038,280,1234 -0.015336908887356353,0.17410512476192191,0.24801958368154803,0.9027628846125711,1.2474172170623723,0.6027831121744145,1.1247147016520551,-0.33327939055474815,0.9990456262708737,0.9990456262708737,0.1367560507410777,0.9671485853633185,0.428393191730484,2.0333215775625626,0.2111917997668451,-0.3743938386878874,-0.5848621144923504,-0.21180894066884262,0.6709474376181863,0.6709474376181863,0.32091216739564127,0.2111917997668451,0.02309828334687722,0.463737560425262,0.32091216739564127,-0.1719280959561597,0.02309828334687722,-0.5848621144923504,0.8375726207273704,1.7387054861501252,0.8375726207273704,-0.8941728675715074,0.5337207971688037,0.9671485853633185,-0.759418488288081,0.3928095936133701,-0.7152427522665485,-0.5848621144923504,0.9671485853633185,0.3928095936133701,0.8046697182564764,0.49884576098804173,1.155663166669387,0.9350551147231273,0.1367560507410777,0.5337207971688037,0.5337207971688037,-0.4996758503153541,0.17410512476192191,0.463737560425262,0.6709474376181863,0.8375726207273704,-0.33327939055474815,0.6369761233848037,-0.7152427522665485,-0.015336908887356353,0.24801958368154803,0.704699791414857,-0.6714285051358926,0.428393191730484,0.17410512476192191,0.704699791414857,-0.13234464502495924,0.28459191556669194,0.463737560425262,0.32091216739564127,1.0307485270519672,0.2111917997668451 2937 Transport of small molecules 28 141 2.621969931587085 0.0087423143683544 P08183,Q8WTV0,P40855,Q9Y6M7,O00231,P35610,Q8NE71,P53985,Q86VP6,Q70HW3,P09601,O43242,P30519,P35611,Q10713,P49721,O15118,Q9H4A3,P56589,Q15008,P51665,P28072,P28074,P45880,P21796,P28070,Q99623,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 8,10,264,148,149,154,299,161,296,294,34,165,41,287,179,50,173,57,70,201,198,326,327,329,99,105,377,253 149,1106,560,1353,173,165,636,2570,919,2171,2068,1678,1237,1411,732,2069,2305,594,2503,8,984,535,34,1306,2353,2125,2306,1641,1243,824,362,2077,773,735,1244,1416,596,99,1183,926,1184,1418,876,105,326,327,1308,41,1845,1928,2081,154,287,420,686,1310,2082,2930,1479,264,1480,329,539,884,50,198,1125,1372,1599,161,1987,1429,834,1934,70,1431,1856,1989,2926,477,1374,1127,2871,2848,1546,1259,1547,2036,837,508,890,179,2743,745,510,1605,1736,1006,840,201,1334,2448,2556,1557,294,296,2328,2004,299,2619,1503,10,709,578,2048,1088,1748,1345,253,549,377,1709,1564,1565,2524,2009,57,964,1398,1100,2593,971,909,811,767,1916,2250,1719,1295,1038,148 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,1.2776448956782354,1.3076973767692464,0.5683656165997513,-0.9859257988083908,0.35698364577547,-0.5420991063561916,-0.4575872142200032,-0.13234464502495924,0.17410512476192191,0.0612563185418274,0.49884576098804173,-0.4575872142200032,-0.6714285051358926,0.6027831121744145,-0.8941728675715074,4.383977831042348,0.32091216739564127,0.6709474376181863,2.871469999732692,0.1367560507410777,-0.7152427522665485,-0.4996758503153541,-0.6714285051358926,-0.09305436959858496,0.17410512476192191,0.428393191730484,0.8702695242261951,-0.4575872142200032,0.463737560425262,0.49884576098804173,0.17410512476192191,0.0612563185418274,0.6027831121744145,1.7110652769447776,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.1367560507410777,2.5760533056071075,-0.2519914877556342,-0.33327939055474815,-0.4575872142200032,1.3672844525092513,0.9990456262708737,0.8046697182564764,0.5337207971688037,0.1367560507410777,-0.4575872142200032,-4.749744545709802,0.02309828334687722,1.0307485270519672,0.02309828334687722,0.9350551147231273,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.24801958368154803,0.09914099907683403,-0.05405313922784484,1.33757659471794,-0.3743938386878874,0.0612563185418274,0.428393191730484,-0.33327939055474815,1.9809980490909074,0.0612563185418274,-0.2519914877556342,-0.3743938386878874,-3.311909712172878,0.7382358716884349,0.09914099907683403,0.24801958368154803,-1.8904581760074333,-1.7288348009106087,-0.015336908887356353,0.17410512476192191,-0.015336908887356353,-0.4158281796670899,0.428393191730484,0.704699791414857,0.3928095936133701,1.2776448956782354,-1.3199640839408484,0.49884576098804173,0.704699791414857,-0.05405313922784484,-0.1719280959561597,0.32091216739564127,0.428393191730484,1.1864283685836194,0.1367560507410777,-0.8039614683338043,-0.9398534966833773,-0.015336908887356353,0.9990456262708737,0.9990456262708737,-0.6714285051358926,-0.3743938386878874,0.9990456262708737,-1.0323962561974658,0.02309828334687722,4.351275402719301,0.5337207971688037,0.6369761233848037,-0.4158281796670899,0.28459191556669194,-0.1719280959561597,0.1367560507410777,1.0622595380909912,0.6709474376181863,0.8702695242261951,-0.13234464502495924,-0.015336908887356353,-0.015336908887356353,-0.8941728675715074,-0.3743938386878874,2.161837222901003,0.35698364577547,0.09914099907683403,0.28459191556669194,-0.9859257988083908,0.35698364577547,0.3928095936133701,0.463737560425262,0.49884576098804173,-0.29248013870191797,-0.5848621144923504,-0.13234464502495924,0.17410512476192191,0.32091216739564127,1.4261935465788533 2937 Coated vesicle 23 81 2.61936965966747 0.0088092429773984 O00443,Q5VW38,Q5VYK3,P20645,Q7Z7H5,O94979,P09496,P48444,P49257,Q9NR31,P50570,Q8N511,P24390,Q9UJY4,Q9Y282,Q14108,P61923,O60763,P42892,Q9BVK6,P04439,Q9UJU6,Q00610 Localization GO Cellular component msigdb_gocc 486,15,270,25,162,284,535,538,541,582,308,186,67,466,81,79,96,219,106,521,232,120,508 585,1969,486,1236,1109,1471,2802,219,2814,1924,1678,284,2870,1303,1411,1054,732,232,535,1837,1415,2681,823,1178,563,25,67,1188,106,538,541,993,308,1598,1124,1728,1485,783,997,1599,1729,2228,2230,1542,96,1546,508,2412,892,2232,1941,79,1554,700,701,15,270,842,162,186,1812,1748,521,760,1218,1030,1622,582,968,1285,1286,2536,120,466,1672,81,1104,1105,813,1038,1234 0.6027831121744145,-0.3743938386878874,0.704699791414857,0.17410512476192191,0.24801958368154803,0.02309828334687722,-1.5205468840168608,1.1247147016520551,-1.5718746398609995,-0.33327939055474815,-0.13234464502495924,0.9990456262708737,-1.8904581760074333,0.1367560507410777,0.0612563185418274,0.28459191556669194,0.49884576098804173,1.0935808714347506,0.6709474376181863,-0.2519914877556342,0.0612563185418274,-1.1742638113510904,0.428393191730484,0.2111917997668451,0.6369761233848037,3.2128208825072786,2.0333215775625626,0.2111917997668451,1.6832758718136789,0.6709474376181863,0.6709474376181863,0.32091216739564127,0.9671485853633185,-0.05405313922784484,0.24801958368154803,-0.1719280959561597,0.02309828334687722,0.463737560425262,0.32091216739564127,-0.05405313922784484,-0.1719280959561597,-0.5848621144923504,-0.5848621144923504,-0.015336908887356353,1.7387054861501252,-0.015336908887356353,0.704699791414857,-0.759418488288081,0.3928095936133701,-0.5848621144923504,-0.33327939055474815,1.901497527876068,-0.015336908887356353,0.5337207971688037,0.5337207971688037,3.994138285325319,1.0307485270519672,0.428393191730484,1.33757659471794,1.2474172170623723,-0.21180894066884262,-0.1719280959561597,0.704699791414857,0.49884576098804173,0.2111917997668451,0.32091216739564127,-0.05405313922784484,0.6369761233848037,0.35698364577547,0.17410512476192191,0.17410512476192191,-0.8941728675715074,1.5705949318057502,0.7715583169098631,-0.09305436959858496,1.901497527876068,0.28459191556669194,0.28459191556669194,0.463737560425262,0.32091216739564127,0.2111917997668451 2937 Autophagy 13 41 2.598946262292533 0.0093510410649608 P07900,Q15382,P21796,Q9NS69,Q9Y6G9,P42345,Q9UBN7,P04350,Q13409,Q9NT62,P08238,Q8N4H5,O43237 Processes and pathways Reactome Pathways msigdb_reactome 245,132,99,7,280,265,80,305,311,257,306,60,182 182,1634,2720,2399,1359,2501,305,245,306,414,823,1887,1478,99,265,1934,691,2511,1731,1002,311,747,332,132,1136,2867,60,2764,960,2378,1346,1347,1568,1153,7,257,1227,80,1517,2873,280 1.2474172170623723,-0.09305436959858496,-1.2709592380232988,-0.759418488288081,0.09914099907683403,-0.8941728675715074,0.9671485853633185,1.0622595380909912,0.9671485853633185,0.8046697182564764,0.428393191730484,-0.29248013870191797,0.02309828334687722,1.7110652769447776,1.0307485270519672,-0.33327939055474815,0.5337207971688037,-0.8941728675715074,-0.1719280959561597,0.32091216739564127,0.9671485853633185,0.49884576098804173,0.9350551147231273,1.5133178288044788,0.24801958368154803,-1.8360492193607452,2.1108177774831414,-1.3694172456596465,0.35698364577547,-0.7152427522665485,0.1367560507410777,0.1367560507410777,-0.015336908887356353,0.24801958368154803,4.432627557673481,1.0622595380909912,0.2111917997668451,1.901497527876068,0.02309828334687722,-1.8904581760074333,1.0307485270519672 2937 Retinoblastoma gene in cancer 18 46 2.5940135410798963 0.0094862750652402 P33991,P11802,Q14566,O95347,P00374,P33981,Q9UQE7,P04818,P16949,P09429,P26358,P35244,P06493,P31350,P49642,P26583,Q16204,P56282 Processes and pathways WikiPathways msigdb_wp 246,158,290,166,103,499,279,445,143,415,449,450,263,498,390,86,268,89 1679,1302,166,103,2025,445,263,415,1639,2124,158,1782,873,143,925,775,826,449,86,875,498,499,246,537,450,2131,2507,2222,390,647,89,999,1000,839,1602,935,2609,1133,290,788,268,1959,1224,912,279,2392 -0.13234464502495924,0.1367560507410777,1.3076973767692464,1.6832758718136789,-0.4158281796670899,0.7715583169098631,1.0307485270519672,0.8046697182564764,-0.09305436959858496,-0.4996758503153541,1.33757659471794,-0.21180894066884262,0.3928095936133701,1.4261935465788533,0.35698364577547,0.463737560425262,0.428393191730484,0.7715583169098631,1.8478045517497095,0.3928095936133701,0.704699791414857,0.704699791414857,1.0622595380909912,0.6709474376181863,0.7715583169098631,-0.4996758503153541,-0.8941728675715074,-0.5848621144923504,0.8375726207273704,0.5683656165997513,1.8207460887469624,0.32091216739564127,0.32091216739564127,0.428393191730484,-0.05405313922784484,0.35698364577547,-1.0323962561974658,0.24801958368154803,0.9990456262708737,0.463737560425262,1.0307485270519672,-0.33327939055474815,0.2111917997668451,0.3928095936133701,1.0307485270519672,-0.7152427522665485 2937 Proteasome component (PCI) domain [IPR000717] 11 19 2.589860122674871 0.0096014936974899 Q9Y262,Q9UBW8,Q99627,O43242,A6NKF1,Q15008,Q9BT78,P48556,Q14152,O00231,P60228 Sequence InterPro Domain interpro_domain 467,276,133,165,441,201,272,539,180,149,564 441,149,1106,165,539,564,602,1326,180,201,1140,2455,133,272,1877,276,767,1916,467 0.7715583169098631,1.3968228224013606,0.24801958368154803,1.3076973767692464,0.6709474376181863,0.6369761233848037,0.6027831121744145,0.1367560507410777,1.2776448956782354,1.1864283685836194,0.24801958368154803,-0.8039614683338043,1.5133178288044788,1.0307485270519672,-0.2519914877556342,1.0307485270519672,0.49884576098804173,-0.29248013870191797,0.7715583169098631 2937 Endothelium development 10 20 2.587920875467593 0.0096557157485623 P15311,P62820,P35241,P35611,P26038,O14786,P18206,Q06330,Q07157,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 134,395,76,287,176,118,209,125,479,61 118,1919,2542,134,209,1783,176,2130,76,287,503,886,931,395,1731,125,479,2318,1963,61 1.5705949318057502,-0.33327939055474815,-0.9398534966833773,1.484439279959394,1.155663166669387,-0.21180894066884262,1.2776448956782354,-0.4996758503153541,1.9281348523770536,0.9990456262708737,0.704699791414857,0.3928095936133701,0.35698364577547,0.8375726207273704,-0.1719280959561597,1.5420358124097335,0.7382358716884349,-0.6714285051358926,-0.33327939055474815,2.1108177774831414 2937 Dendrite development 8 46 2.587371916888398 0.0096711143205028 P78344,Q13177,Q9UBN7,Q9UQB8,O14786,Q6SZW1,Q9UJU6,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 68,139,80,18,118,87,120,61 1764,118,2395,2863,1770,1412,1681,2261,825,1364,1064,2084,645,1251,1852,1254,1067,931,68,1937,889,566,1199,139,1941,428,2092,2512,2447,87,1698,1142,2485,1213,1755,1757,1397,80,120,2297,631,194,18,1716,1881,61 -0.21180894066884262,1.5705949318057502,-0.759418488288081,-1.8360492193607452,-0.21180894066884262,0.0612563185418274,-0.13234464502495924,-0.6279701240574134,0.428393191730484,0.09914099907683403,0.28459191556669194,-0.4575872142200032,0.5683656165997513,0.17410512476192191,-0.2519914877556342,0.17410512476192191,0.28459191556669194,0.35698364577547,2.0333215775625626,-0.33327939055474815,0.3928095936133701,0.6369761233848037,0.2111917997668451,1.455398437788666,-0.33327939055474815,0.8046697182564764,-0.4575872142200032,-0.8941728675715074,-0.8039614683338043,1.8478045517497095,-0.13234464502495924,0.24801958368154803,-0.8488775839823314,0.2111917997668451,-0.1719280959561597,-0.1719280959561597,0.09914099907683403,1.901497527876068,1.5705949318057502,-0.6279701240574134,0.6027831121744145,1.2170123744522818,3.7962488360202657,-0.13234464502495924,-0.2519914877556342,2.1108177774831414 2937 Protein autophosphorylation 13 31 2.5851806863108915 0.009732797779284 P05198,P33981,Q13177,Q9NYV4,P42345,P41240,O15164,Q9C0C2,Q13546,Q99986,Q9H2G2,Q05682,P27708 Processes and pathways GO Biological process msigdb_gobp 594,499,139,241,265,370,411,523,510,550,189,59,496 1721,1767,411,1923,921,1053,594,824,1532,828,496,499,1846,370,265,1251,1596,1937,59,139,1263,510,1736,2093,2046,1275,550,523,189,241,720 -0.1719280959561597,-0.21180894066884262,0.8046697182564764,-0.33327939055474815,0.35698364577547,0.28459191556669194,0.6027831121744145,0.428393191730484,-0.015336908887356353,0.428393191730484,0.704699791414857,0.704699791414857,-0.2519914877556342,0.8702695242261951,1.0307485270519672,0.17410512476192191,-0.05405313922784484,-0.33327939055474815,2.1363911463999377,1.455398437788666,0.17410512476192191,0.704699791414857,-0.1719280959561597,-0.4575872142200032,-0.4158281796670899,0.17410512476192191,0.6709474376181863,0.704699791414857,1.2474172170623723,1.0935808714347506,0.5337207971688037 2937 Microtubule associated complex 25 40 2.5841665569386087 0.0097614641816488 P27816,Q9Y6G9,P61163,P52732,Q9H6D7,P46821,O75935,Q96P70,Q13409,Q9NZ32,O43237,O95793,O15344,Q14204,Q9UBN7,P42025,Q14203,Q9H0B6,Q13561,P33176,Q15555,P12270,O94927,Q9UJW0,Q9Y496 Localization GO Cellular component msigdb_gocc 497,280,393,648,164,645,283,580,311,855,182,561,816,332,80,689,211,92,895,473,348,104,592,528,259 1968,1767,816,182,283,592,561,104,497,1309,473,689,1064,645,648,393,2511,2607,1074,311,895,211,332,2794,2184,348,1205,2153,580,1344,2106,1667,92,164,855,80,528,914,259,280 -0.3743938386878874,-0.21180894066884262,0.428393191730484,1.2474172170623723,0.9990456262708737,0.6027831121744145,0.6369761233848037,1.6832758718136789,0.704699791414857,0.1367560507410777,0.7382358716884349,0.5337207971688037,0.28459191556669194,0.5683656165997513,0.5683656165997513,0.8375726207273704,-0.8941728675715074,-1.0323962561974658,0.28459191556669194,0.9671485853633185,0.3928095936133701,1.155663166669387,0.9350551147231273,-1.469700408349865,-0.5420991063561916,0.9027628846125711,0.2111917997668451,-0.4996758503153541,0.6369761233848037,0.1367560507410777,-0.4575872142200032,-0.09305436959858496,1.8207460887469624,1.33757659471794,0.428393191730484,1.901497527876068,0.704699791414857,0.3928095936133701,1.0622595380909912,1.0307485270519672 2937 Transporters 57 320 2.577332698554187 0.0099566066797767 O43772,P08183,Q8WTV0,Q8IXU6,Q9NR77,Q5VW38,Q5BJF2,P40855,O95563,P06493,Q9Y6M7,P07602,O95342,Q99720,P61221,P20645,Q96A65,Q9BTX1,P53985,Q6N075,Q8NE71,Q70HW3,O94979,Q15629,O14828,Q07065,P55060,O60826,O60637,O15118,Q8TBA6,Q9H2D1,P50570,Q8N511,P08238,Q96NB2,P24390,Q9H061,P56589,Q969V3,Q14108,O15397,P13073,O15127,Q92544,P45880,Q16543,Q8N1F7,P12270,O75844,Q16799,P04439,O95373,O14786,Q9NT62,Q8WY22,P81605 Functions Protein Atlas Protein class protein_atlas_protein_class 4,8,10,11,13,15,16,264,262,263,148,151,22,23,267,25,300,156,161,30,299,294,284,39,281,178,288,175,174,173,314,188,308,186,306,338,67,207,70,337,79,195,77,320,91,329,228,350,104,102,111,232,244,118,257,127,124 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2937 Alzheimers disease 31 80 2.5740357790838737 0.0100519877723408 Q13564,P48729,P49327,P42345,O14654,Q99460,O43242,O95197,P48556,P49721,P04350,P35998,O00487,Q15008,P51665,P28072,P28074,P62191,P45880,Q9H0B6,P33176,P05198,P21796,P28070,Q16186,Q9UNM6,Q13885,Q13200,P17980,Q99436,Q9NQC3 Processes and pathways WikiPathways msigdb_wp 654,502,503,265,633,549,165,532,539,50,305,686,560,201,198,326,327,477,329,92,473,594,99,105,515,767,747,745,362,253,526 1106,560,633,1353,1919,165,532,2502,305,1360,2305,594,1474,1057,1529,2125,2306,1242,1243,1180,362,1532,1478,735,99,1182,1183,926,1184,1418,828,876,105,326,327,1247,2605,878,473,2130,686,1846,265,1312,1480,329,539,502,503,884,50,1251,198,834,1431,477,1374,1127,1731,1937,1071,2444,1074,891,745,654,747,201,515,2619,1612,253,549,2588,1568,1153,92,526,767,2250 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2937 Malignant genitourinary tract tumor 11 21 2.5724844986585427 0.010097147752035 P52701,P43246,P61254,P62847,P61353,P60866,P62081,P39019,P62899,P46783,P42766 Drugs and Diseases Human Phenotype Ontology msigdb_hp 647,347,136,372,542,504,505,82,83,155,95 1414,682,82,95,347,1189,155,647,1687,504,136,1650,542,505,1489,1689,372,2847,83,1545,1131 0.0612563185418274,0.5337207971688037,1.8747212260962505,1.7387054861501252,0.9027628846125711,0.2111917997668451,1.3672844525092513,0.5683656165997513,-0.13234464502495924,0.704699791414857,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.704699791414857,0.02309828334687722,-0.13234464502495924,0.8702695242261951,-1.7288348009106087,1.8747212260962505,-0.015336908887356353,0.24801958368154803 2937 Exopeptidase activity 12 32 2.5709696607167145 0.0101414210987211 O14773,Q969V3,P42785,Q9UIQ6,P55786,O75844,Q9NY33,Q96KP4,Q9H3G5,Q9HB40,Q13867,Q7Z2K6 Functions GO Molecular function msigdb_gomf 129,337,6,277,135,102,240,213,17,55,427,431 129,102,1775,732,868,2073,1058,2469,2028,1685,6,780,997,135,2268,427,431,2275,621,2281,337,2886,213,482,17,1668,55,2529,629,240,2534,277 1.5133178288044788,1.6832758718136789,-0.21180894066884262,0.49884576098804173,0.3928095936133701,-0.4575872142200032,0.28459191556669194,-0.8488775839823314,-0.4158281796670899,-0.13234464502495924,4.496753993926139,0.463737560425262,0.32091216739564127,1.484439279959394,-0.6279701240574134,0.8046697182564764,0.8046697182564764,-0.6279701240574134,0.6027831121744145,-0.6279701240574134,0.9350551147231273,-2.0009314909515403,1.155663166669387,0.7382358716884349,3.7962488360202657,-0.09305436959858496,2.1871572148884817,-0.8941728675715074,0.6027831121744145,1.0935808714347506,-0.8941728675715074,1.0307485270519672 2937 Nonimmune hydrops fetalis 11 26 2.5535638042622377 0.0106626740837731 Q9BT22,P61254,P62847,P60866,Q14739,P62081,P39019,P62899,P06132,P46783,P42766 Drugs and Diseases Human Phenotype Ontology msigdb_hp 339,136,372,504,48,505,82,83,361,155,95 2543,1052,981,361,1414,2073,682,82,95,1189,155,504,136,1650,542,505,1489,1689,372,2847,83,1545,1131,48,339,2010 -0.9398534966833773,0.28459191556669194,0.32091216739564127,0.8702695242261951,0.0612563185418274,-0.4575872142200032,0.5337207971688037,1.8747212260962505,1.7387054861501252,0.2111917997668451,1.3672844525092513,0.704699791414857,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.704699791414857,0.02309828334687722,-0.13234464502495924,0.8702695242261951,-1.7288348009106087,1.8747212260962505,-0.015336908887356353,0.24801958368154803,2.3609647917690713,0.9350551147231273,-0.3743938386878874 2937 Establishment of endothelial barrier 8 11 2.5523373090095363 0.0107002869701309 P15311,P62820,P35241,P35611,P26038,P18206,Q07157,Q9Y4G8 Processes and pathways GO Biological process msigdb_gobp 134,395,76,287,176,209,479,61 1919,134,209,176,76,287,503,886,395,479,61 -0.33327939055474815,1.484439279959394,1.155663166669387,1.2776448956782354,1.9281348523770536,0.9990456262708737,0.704699791414857,0.3928095936133701,0.8375726207273704,0.7382358716884349,2.1108177774831414 2937 Downstream signaling events of b cell receptor bcr 26 44 2.54734084594947 0.0108547354014487 P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436 Processes and pathways Reactome Pathways msigdb_reactome 884,876,811,149,549,165,539,578,50,840,919,686,560,834,201,198,326,327,477,105,890,767,745,735,362,253 149,1106,560,1353,1919,165,919,2502,2791,362,735,1183,926,1184,1418,876,105,326,327,686,1480,539,884,50,198,834,1431,1856,477,1374,1127,1257,1259,2444,890,745,1006,840,201,578,253,549,811,767 1.3968228224013606,0.24801958368154803,0.6369761233848037,0.09914099907683403,-0.33327939055474815,1.3076973767692464,0.35698364577547,-0.8941728675715074,-1.469700408349865,0.8702695242261951,0.49884576098804173,0.2111917997668451,0.35698364577547,0.2111917997668451,0.0612563185418274,0.3928095936133701,1.6832758718136789,0.9350551147231273,0.9350551147231273,0.5337207971688037,0.02309828334687722,0.6709474376181863,0.3928095936133701,2.237423692928971,1.1864283685836194,0.428393191730484,0.0612563185418274,-0.2519914877556342,0.7382358716884349,0.09914099907683403,0.24801958368154803,0.17410512476192191,0.17410512476192191,-0.8039614683338043,0.3928095936133701,0.49884576098804173,0.32091216739564127,0.428393191730484,1.1864283685836194,0.6369761233848037,1.0622595380909912,0.6709474376181863,0.463737560425262,0.49884576098804173 2937 Vesicle mediated transport 101 297 2.5454060975694706 0.0109150716545085 O00443,Q8WTV0,Q5VW38,Q8IUR0,P20645,Q4J6C6,P09601,P09496,O95197,P48444,P48739,P49257,P50897,P53367,Q96QK1,Q92538,Q9NR31,P35579,P20339,P24390,Q06787,Q4KMP7,Q9Y282,P35241,Q14108,Q92544,P61923,O43617,O00203,Q13614,O14786,Q9UJU6,Q8WUM4,Q7Z3U7,P15311,Q9NZQ3,P42858,Q7Z7H5,Q8IWQ3,Q9H3U1,P26038,O60826,Q9NZZ3,O15118,Q15363,Q15436,Q9UBQ0,Q14849,P30533,Q9UQ16,P15531,Q8TD16,Q0VDF9,P84085,P60520,Q14203,Q8IYI6,Q92905,Q9BXS5,O75165,O60763,Q9H3S7,P62993,Q9NT62,Q68EM7,O60271,Q96A65,O94979,O60749,O14828,Q8TBA6,Q01082,P50570,Q9H4M9,Q9UNH7,O15127,Q99700,O00429,O15498,P41240,P35080,P40222,Q8N6T3,P62820,P61163,Q96JJ3,Q15019,Q9Y5K6,Q9Y2T2,Q08722,P09429,Q9UJY4,Q9UPN3,Q99829,O75122,O14617,Q14C86,Q9BVK6,Q9UPT5,Q9Y4L1,Q00610 Processes and pathways GO Biological process msigdb_gobp 486,10,15,548,25,33,34,535,532,538,540,541,49,51,581,579,582,63,563,67,566,613,81,76,79,91,96,588,585,110,118,120,661,137,134,142,144,162,706,714,176,175,718,173,700,701,719,699,183,194,681,205,695,694,691,211,753,754,760,220,219,762,236,257,251,261,300,284,282,281,314,310,308,340,343,320,353,345,346,370,366,368,401,395,393,434,429,440,438,424,415,466,485,482,471,469,512,521,529,531,508 1039,2119,2120,2907,2801,585,1969,345,486,916,1522,1236,469,118,281,1631,1831,1109,173,320,1769,1970,1406,346,2018,588,1471,2065,978,261,1300,2802,1634,282,219,175,471,220,2814,1924,1773,1677,2255,2657,2024,1678,284,2870,532,2737,1303,2680,1411,732,1473,2722,2261,2791,1413,2703,415,535,1837,34,822,823,2437,2633,1178,2604,134,681,1243,2825,825,1362,563,25,2026,2079,67,176,828,1119,2546,2128,1247,183,777,878,832,366,2130,76,63,1188,2682,1846,368,992,370,882,144,1985,538,540,541,993,1251,1195,308,49,1065,1597,2085,1598,1124,1125,1728,51,1485,783,1599,1729,1486,1934,2228,2315,2086,691,2759,1254,2230,2088,1542,393,96,1791,395,236,1546,1793,694,1733,2036,1937,508,310,932,1071,566,2412,2473,424,695,1001,2268,892,2365,1325,1002,2232,1941,1005,110,1380,2270,79,2581,211,786,699,512,429,1864,1554,2092,700,701,1203,2093,1898,33,613,2448,1270,1271,1866,15,1608,251,2867,946,842,1698,1207,2478,137,162,796,548,706,753,401,2146,2649,2278,1502,314,2422,205,2916,10,2484,661,2764,1953,2047,579,91,2621,754,1388,1812,300,1748,434,581,1090,1751,353,2379,1347,482,1665,2380,521,2488,760,1029,1819,1713,1218,1030,762,714,763,340,1392,2339,1622,582,257,2246,968,1963,1226,2157,142,718,2735,1285,806,856,1286,719,2536,971,857,1516,120,466,1878,2297,2594,1672,1289,1575,1167,343,2208,485,529,194,1403,81,1716,438,1104,1519,1294,531,440,1105,813,1038,1234 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2937 Anion transmembrane transport 9 40 2.5417444687776323 0.0110300780160899 Q96NB2,P21796,Q9UHG3,P08183,Q9Y4C2,O95563,Q9Y6M7,Q9H2D1,P53985 Processes and pathways GO Biological process msigdb_gobp 338,99,38,8,319,262,148,188,161 2066,2021,2303,866,262,2305,2261,8,984,2125,2306,99,1928,329,1125,1372,2509,161,1429,1795,2137,510,1134,789,1334,2448,1503,338,1509,188,1669,1394,1622,1398,38,1965,2250,319,2392,148 -0.4575872142200032,-0.4158281796670899,-0.6714285051358926,0.3928095936133701,1.0307485270519672,-0.6714285051358926,-0.6279701240574134,4.383977831042348,0.32091216739564127,-0.4996758503153541,-0.6714285051358926,1.7110652769447776,-0.33327939055474815,0.9350551147231273,0.24801958368154803,0.09914099907683403,-0.8941728675715074,1.33757659471794,0.0612563185418274,-0.21180894066884262,-0.4996758503153541,0.704699791414857,0.24801958368154803,0.463737560425262,0.1367560507410777,-0.8039614683338043,0.02309828334687722,0.9350551147231273,0.02309828334687722,1.2474172170623723,-0.09305436959858496,0.09914099907683403,-0.05405313922784484,0.09914099907683403,2.691723830472613,-0.33327939055474815,-0.5848621144923504,0.9671485853633185,-0.7152427522665485,1.4261935465788533 2937 Persistence of hemoglobin f 10 20 2.539952675859205 0.0110867469224396 P61254,P62847,P61353,P60866,P62081,P39019,P62899,P46783,P61011,P42766 Drugs and Diseases Human Phenotype Ontology msigdb_hp 136,372,542,504,505,82,83,155,476,95 1414,682,82,95,1189,155,504,476,136,1650,542,505,1489,1689,372,2847,83,1545,1131,632 0.0612563185418274,0.5337207971688037,1.8747212260962505,1.7387054861501252,0.2111917997668451,1.3672844525092513,0.704699791414857,0.7382358716884349,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.704699791414857,0.02309828334687722,-0.13234464502495924,0.8702695242261951,-1.7288348009106087,1.8747212260962505,-0.015336908887356353,0.24801958368154803,0.6027831121744145 2937 Osteosarcoma 9 23 2.5198358399220524 0.0117409576929738 P61254,P62847,P60866,Q13126,P62081,P39019,P62899,P46783,P42766 Drugs and Diseases Human Phenotype Ontology msigdb_hp 136,372,504,145,505,82,83,155,95 1053,980,2025,1414,682,82,95,1189,155,504,136,1650,542,505,1489,1689,372,2847,83,1545,1131,145,1571 0.28459191556669194,0.32091216739564127,-0.4158281796670899,0.0612563185418274,0.5337207971688037,1.8747212260962505,1.7387054861501252,0.2111917997668451,1.3672844525092513,0.704699791414857,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.704699791414857,0.02309828334687722,-0.13234464502495924,0.8702695242261951,-1.7288348009106087,1.8747212260962505,-0.015336908887356353,0.24801958368154803,1.4261935465788533,-0.015336908887356353 2937 Tissue migration 16 48 2.516574218431729 0.011850193888673 P09601,O75122,Q15555,P42785,Q8WTV0,P42345,Q9UBN7,P09429,P06576,P06744,P19174,P35080,Q9UPN3,O14786,Q9NQC3,P35579 Processes and pathways GO Biological process msigdb_gobp 34,471,348,6,10,265,80,415,196,324,234,366,485,118,526,63 486,118,471,2814,1114,1473,2261,196,324,983,415,34,2075,772,234,2178,2080,2546,366,63,1727,265,6,1598,1852,742,931,1731,2579,1077,1861,348,2093,841,1011,943,1270,10,2796,1348,762,2840,526,1224,1963,80,2594,485 0.704699791414857,1.5705949318057502,0.7382358716884349,-1.5718746398609995,0.24801958368154803,0.02309828334687722,-0.6279701240574134,1.1864283685836194,0.9350551147231273,0.32091216739564127,0.8046697182564764,2.871469999732692,-0.4575872142200032,0.463737560425262,1.0935808714347506,-0.5420991063561916,-0.4575872142200032,-0.9398534966833773,0.8702695242261951,2.085115891068643,-0.1719280959561597,1.0307485270519672,4.496753993926139,-0.05405313922784484,-0.2519914877556342,0.49884576098804173,0.35698364577547,-0.1719280959561597,-0.9859257988083908,0.28459191556669194,-0.2519914877556342,0.9027628846125711,-0.4575872142200032,0.428393191730484,0.32091216739564127,0.35698364577547,0.17410512476192191,4.351275402719301,-1.469700408349865,0.1367560507410777,0.49884576098804173,-1.6760094336606017,0.704699791414857,0.2111917997668451,-0.33327939055474815,1.901497527876068,-0.9859257988083908,0.7382358716884349 2937 Negative regulation of cellular component organization 43 153 2.516417446005889 0.0118554670404971 P27816,P33981,Q13177,Q9NR77,Q9Y6G9,P16949,Q99536,Q9BTW9,P30536,P33993,Q13813,P35611,P08670,P09429,Q96QK1,Q01082,P50570,P04350,Q9Y4G8,P30533,Q9UQ16,P41227,P61758,P35241,P53384,Q9UBN7,Q9UHV9,P45880,Q99700,Q07157,Q13045,O75122,P12270,Q9P265,Q15645,Q13614,Q92974,Q9NQ88,P35080,O14786,Q02790,Q9NUQ9,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 497,499,139,13,280,143,146,163,160,537,426,287,414,415,581,310,308,305,61,183,194,73,453,76,331,80,484,329,353,479,226,471,104,242,514,110,519,525,366,118,509,128,526 915,1721,118,1919,1831,816,2018,863,1633,2064,2170,1833,1883,1300,2216,1923,471,1924,919,1114,867,980,732,981,305,2025,2305,1976,1413,983,2504,414,415,2824,922,822,823,2124,104,871,873,143,2026,1182,2877,497,1309,2605,183,160,777,832,499,537,366,76,287,2356,1645,73,2683,1064,329,1647,645,2226,1787,779,690,1251,1195,308,2085,1196,1484,331,1318,1254,601,931,453,2511,1937,1796,310,2363,509,889,479,1379,226,2269,139,2318,1941,110,426,938,2320,2184,2092,514,1010,951,752,1142,1014,1953,1706,2485,1275,902,519,2777,852,961,1750,581,799,1346,146,353,853,1348,163,2054,2625,1961,525,526,13,128,2204,1963,583,2343,1825,805,242,80,1100,1399,484,2537,1878,1761,2594,2887,1167,1917,194,61,280 0.35698364577547,-0.1719280959561597,1.5705949318057502,-0.33327939055474815,-0.2519914877556342,0.428393191730484,-0.4158281796670899,0.3928095936133701,-0.09305436959858496,-0.4575872142200032,-0.5420991063561916,-0.2519914877556342,-0.29248013870191797,0.1367560507410777,-0.5848621144923504,-0.33327939055474815,0.7382358716884349,-0.33327939055474815,0.35698364577547,0.24801958368154803,0.3928095936133701,0.32091216739564127,0.49884576098804173,0.32091216739564127,0.9671485853633185,-0.4158281796670899,-0.6714285051358926,-0.3743938386878874,0.0612563185418274,0.32091216739564127,-0.8941728675715074,0.8046697182564764,0.8046697182564764,-1.623692476299974,0.35698364577547,0.428393191730484,0.428393191730484,-0.4996758503153541,1.6832758718136789,0.3928095936133701,0.3928095936133701,1.4261935465788533,-0.4158281796670899,0.2111917997668451,-1.9454153738987696,0.704699791414857,0.1367560507410777,-1.0323962561974658,1.2474172170623723,1.33757659471794,0.463737560425262,0.428393191730484,0.704699791414857,0.6709474376181863,0.8702695242261951,1.9281348523770536,0.9990456262708737,-0.7152427522665485,-0.09305436959858496,1.9546345744878875,-1.1742638113510904,0.28459191556669194,0.9350551147231273,-0.09305436959858496,0.5683656165997513,-0.5848621144923504,-0.21180894066884262,0.463737560425262,0.5337207971688037,0.17410512476192191,0.2111917997668451,0.9671485853633185,-0.4575872142200032,0.2111917997668451,0.02309828334687722,0.9350551147231273,0.1367560507410777,0.17410512476192191,0.6027831121744145,0.35698364577547,0.7715583169098631,-0.8941728675715074,-0.33327939055474815,-0.21180894066884262,0.9671485853633185,-0.7152427522665485,0.704699791414857,0.3928095936133701,0.7382358716884349,0.09914099907683403,1.1247147016520551,-0.6279701240574134,1.455398437788666,-0.6714285051358926,-0.33327939055474815,1.655335720828877,0.8046697182564764,0.35698364577547,-0.6714285051358926,-0.5420991063561916,-0.4575872142200032,0.704699791414857,0.32091216739564127,0.35698364577547,0.49884576098804173,0.24801958368154803,0.32091216739564127,-0.33327939055474815,-0.13234464502495924,-0.8488775839823314,0.17410512476192191,0.3928095936133701,0.704699791414857,-1.4193266439978673,0.428393191730484,0.35698364577547,-0.1719280959561597,0.6369761233848037,0.463737560425262,0.1367560507410777,1.4261935465788533,0.9027628846125711,0.428393191730484,0.1367560507410777,1.33757659471794,-0.4158281796670899,-1.0323962561974658,-0.33327939055474815,0.704699791414857,0.704699791414857,4.2518449635579465,1.5420358124097335,-0.5420991063561916,-0.33327939055474815,0.6369761233848037,-0.6714285051358926,-0.21180894066884262,0.463737560425262,1.0935808714347506,1.901497527876068,0.28459191556669194,0.09914099907683403,0.7382358716884349,-0.8941728675715074,-0.2519914877556342,-0.1719280959561597,-0.9859257988083908,-2.0009314909515403,0.24801958368154803,-0.29248013870191797,1.2170123744522818,2.1108177774831414,1.0307485270519672 2937 Protease 19 83 2.5142436015177543 0.0119288006047704 O14773,P42785,Q9UIQ6,P55786,Q9H3G5,Q13867,Q7Z2K6,Q4J6C6,Q9HB40,Q9UPU5,Q96KP4,P28072,P28074,P42892,O75844,Q9NY33,Q16740,Q99436,P81605 Functions Protein Atlas Molecular function protein_atlas_molecular_function 129,6,277,135,17,427,431,33,55,191,213,326,327,106,102,240,237,253,124 1521,560,129,917,2570,102,1775,1636,1357,920,1474,868,2073,1058,1242,1180,326,327,2469,2028,687,1932,1312,6,106,1481,1594,780,2686,1986,2407,997,998,135,2409,1375,124,427,2320,1606,1653,237,33,459,1947,1999,1496,431,2275,1274,2189,2916,1387,754,959,1388,1615,1148,1276,798,213,1345,253,1346,1709,1028,17,1668,2528,55,2529,629,2716,240,2534,2294,277,191,673,2873,1295,1233,1296 -0.015336908887356353,0.6369761233848037,1.5133178288044788,0.35698364577547,-0.9859257988083908,1.6832758718136789,-0.21180894066884262,-0.09305436959858496,0.09914099907683403,0.35698364577547,0.02309828334687722,0.3928095936133701,-0.4575872142200032,0.28459191556669194,0.17410512476192191,0.2111917997668451,0.9350551147231273,0.9350551147231273,-0.8488775839823314,-0.4158281796670899,0.5337207971688037,-0.33327939055474815,0.1367560507410777,4.496753993926139,1.6832758718136789,0.02309828334687722,-0.05405313922784484,0.463737560425262,-1.1742638113510904,-0.3743938386878874,-0.759418488288081,0.32091216739564127,0.32091216739564127,1.484439279959394,-0.759418488288081,0.09914099907683403,1.5420358124097335,0.8046697182564764,-0.6714285051358926,-0.05405313922784484,-0.09305436959858496,1.0935808714347506,2.959000560087587,0.7715583169098631,-0.33327939055474815,-0.3743938386878874,0.02309828334687722,0.8046697182564764,-0.6279701240574134,0.17410512476192191,-0.5420991063561916,-2.589360161351481,0.09914099907683403,0.49884576098804173,0.35698364577547,0.09914099907683403,-0.05405313922784484,0.24801958368154803,0.17410512476192191,0.463737560425262,1.155663166669387,0.1367560507410777,1.0622595380909912,0.1367560507410777,-0.13234464502495924,0.32091216739564127,3.7962488360202657,-0.09305436959858496,-0.8941728675715074,2.1871572148884817,-0.8941728675715074,0.6027831121744145,-1.222394988641525,1.0935808714347506,-0.8941728675715074,-0.6279701240574134,1.0307485270519672,1.2474172170623723,0.5683656165997513,-1.8904581760074333,0.17410512476192191,0.2111917997668451,0.17410512476192191 2937 Neuron death 22 73 2.506333638775557 0.0121990448982578 P45985,Q99720,Q9UMX5,Q01105,P09601,P49917,Q04637,P50897,P51858,P08238,Q15392,Q96A26,Q9UNH7,P06744,P62191,Q6SZW1,P43246,Q15233,Q9NQ88,O43813,O14786,Q9Y4L1 Processes and pathways GO Biological process msigdb_gobp 501,23,26,28,34,168,171,49,58,306,202,206,343,324,477,87,347,513,525,112,118,531 2302,118,112,864,866,1835,920,1051,981,2874,1360,2025,594,324,306,34,922,1118,1180,2178,2079,878,832,2130,1312,347,501,779,2311,600,503,1192,1251,168,49,1852,58,1254,1935,931,477,1546,1793,2362,1937,28,2808,171,2849,1327,1941,654,2184,513,202,87,1612,2196,206,2151,581,1346,23,2829,525,2862,720,1715,1761,26,343,975,531 -0.6714285051358926,1.5705949318057502,1.627243250148423,0.3928095936133701,0.3928095936133701,-0.2519914877556342,0.35698364577547,0.28459191556669194,0.32091216739564127,-1.9454153738987696,0.09914099907683403,-0.4158281796670899,0.6027831121744145,0.9350551147231273,0.9671485853633185,2.871469999732692,0.35698364577547,0.24801958368154803,0.2111917997668451,-0.5420991063561916,-0.4575872142200032,0.3928095936133701,0.428393191730484,-0.4996758503153541,0.1367560507410777,0.9027628846125711,0.704699791414857,0.463737560425262,-0.6714285051358926,0.6027831121744145,0.704699791414857,0.2111917997668451,0.17410512476192191,1.3076973767692464,2.3364949483641926,-0.2519914877556342,2.1363911463999377,0.17410512476192191,-0.33327939055474815,0.35698364577547,0.7382358716884349,-0.015336908887356353,-0.21180894066884262,-0.7152427522665485,-0.33327939055474815,3.0663191302423836,-1.5205468840168608,1.3076973767692464,-1.7288348009106087,0.1367560507410777,-0.33327939055474815,0.5683656165997513,-0.5420991063561916,0.704699791414857,1.1864283685836194,1.8478045517497095,-0.05405313922784484,-0.5420991063561916,1.1864283685836194,-0.4996758503153541,0.6369761233848037,0.1367560507410777,3.434730873938129,-1.623692476299974,0.704699791414857,-1.7821781247895743,0.5337207971688037,-0.13234464502495924,-0.1719280959561597,3.192151726462137,0.9350551147231273,0.35698364577547,0.704699791414857 2937 G-protein modulator 9 24 2.492611299363722 0.0126807580919361 Q13576,P46940,Q9H4M9,Q14C86,P43487,P52565,P53367,Q86VI3,Q9Y4G8 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 545,131,340,512,388,371,51,313,61 814,1630,2178,882,388,1536,131,1891,371,51,567,545,512,701,950,1698,313,1505,1506,1219,340,1620,61,2299 0.428393191730484,-0.09305436959858496,-0.5420991063561916,0.3928095936133701,0.8375726207273704,-0.015336908887356353,1.5133178288044788,-0.29248013870191797,0.8702695242261951,2.237423692928971,0.6369761233848037,0.6709474376181863,0.704699791414857,0.5337207971688037,0.35698364577547,-0.13234464502495924,0.9671485853633185,0.02309828334687722,0.02309828334687722,0.2111917997668451,0.9350551147231273,-0.05405313922784484,2.1108177774831414,-0.6279701240574134 2937 Cytosolic ribosome 35 80 2.488447649117357 0.0128302124884123 P46778,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P42766,P61927,P05198,P62829,Q9Y3U8,P62847,Q9BY44,P35268,P62269,P46782,P62910,P46779,P62241 Localization GO Cellular component msigdb_gocc 737,136,504,505,506,384,387,389,155,650,649,289,423,542,562,680,682,835,454,82,83,325,95,604,594,607,243,372,904,367,887,599,888,738,743 594,2603,562,1638,1414,680,1530,682,874,1477,384,1245,325,1419,1644,1931,367,1311,82,387,1645,95,389,1189,737,738,1482,599,155,1314,927,1933,1789,504,1197,136,1650,542,1432,604,505,743,1489,1857,1936,1433,887,1689,649,506,1128,454,423,1544,607,1792,372,1320,2847,1256,83,835,888,1545,650,2761,2548,2181,1600,289,1651,1691,1549,1131,2555,1208,904,2052,1222,243 0.6027831121744145,-1.0323962561974658,0.6369761233848037,-0.09305436959858496,0.0612563185418274,0.5337207971688037,-0.015336908887356353,0.5337207971688037,0.3928095936133701,0.02309828334687722,0.8375726207273704,0.17410512476192191,0.9350551147231273,0.0612563185418274,-0.09305436959858496,-0.33327939055474815,0.8702695242261951,0.1367560507410777,1.8747212260962505,0.8375726207273704,-0.09305436959858496,1.7387054861501252,0.8375726207273704,0.2111917997668451,0.49884576098804173,0.49884576098804173,0.02309828334687722,0.6027831121744145,1.3672844525092513,0.1367560507410777,0.35698364577547,-0.33327939055474815,-0.21180894066884262,0.704699791414857,0.2111917997668451,1.484439279959394,-0.09305436959858496,0.6709474376181863,0.0612563185418274,0.6027831121744145,0.704699791414857,0.49884576098804173,0.02309828334687722,-0.2519914877556342,-0.33327939055474815,0.0612563185418274,0.3928095936133701,-0.13234464502495924,0.5683656165997513,0.704699791414857,0.24801958368154803,0.7715583169098631,0.8046697182564764,-0.015336908887356353,0.6027831121744145,-0.21180894066884262,0.8702695242261951,0.1367560507410777,-1.7288348009106087,0.17410512476192191,1.8747212260962505,0.428393191730484,0.3928095936133701,-0.015336908887356353,0.5683656165997513,-1.3694172456596465,-0.9398534966833773,-0.5420991063561916,-0.05405313922784484,0.9990456262708737,-0.09305436959858496,-0.13234464502495924,-0.015336908887356353,0.24801958368154803,-0.9398534966833773,0.2111917997668451,0.3928095936133701,-0.4158281796670899,0.2111917997668451,1.0935808714347506 2937 Site of polarized growth 20 41 2.486493533129503 0.0129008914313619 P07900,P46940,Q99720,Q96A65,P46821,P53621,Q14247,P50570,P08238,Q06787,Q96A49,Q8IYI6,P78310,Q9BTU6,Q13561,Q9UPT5,Q02790,Q7Z406,Q9UJU6,O75312 Localization GO Cellular component msigdb_gocc 245,131,23,300,645,783,786,308,306,566,212,753,478,354,895,529,509,119,120,864 2397,864,245,306,2026,2079,1119,1064,645,131,308,1371,1789,783,478,1129,1937,509,566,1074,895,938,786,2447,2040,1698,119,753,1502,1811,959,212,300,1506,23,354,1397,1286,120,529,1294 -0.759418488288081,0.3928095936133701,1.0622595380909912,0.9671485853633185,-0.4158281796670899,-0.4575872142200032,0.24801958368154803,0.28459191556669194,0.5683656165997513,1.5133178288044788,0.9671485853633185,0.09914099907683403,-0.21180894066884262,0.463737560425262,0.7382358716884349,0.24801958368154803,-0.33327939055474815,0.704699791414857,0.6369761233848037,0.28459191556669194,0.3928095936133701,0.35698364577547,0.463737560425262,-0.8039614683338043,-0.4158281796670899,-0.13234464502495924,1.5705949318057502,0.49884576098804173,0.02309828334687722,-0.21180894066884262,0.35698364577547,1.155663166669387,0.9990456262708737,0.02309828334687722,3.434730873938129,0.9027628846125711,0.09914099907683403,0.17410512476192191,1.5705949318057502,0.704699791414857,0.17410512476192191 2937 Regulation of cellular component movement 34 126 2.484964251773778 0.0129564444741656 O00443,P14174,P42785,Q8WTV0,P42345,P16949,O60271,Q5VTR2,P09601,Q08722,Q9Y4C2,P09429,P26038,Q9H4A3,Q9H2G2,Q9Y4G8,P35241,Q9UBN7,P06576,P06744,P39019,Q9H9T3,Q9UPN3,P18206,Q07157,O75122,O00429,Q15555,Q92974,P19174,P35080,O14786,Q9NUQ9,Q9NQC3 Processes and pathways GO Biological process msigdb_gobp 486,122,6,10,265,143,261,269,34,424,319,415,176,57,189,61,76,80,196,324,82,214,485,209,479,471,345,348,519,234,366,118,128,526 1968,1041,345,486,1108,118,726,261,488,471,637,2814,2599,1301,1114,1680,921,980,1473,2874,2722,2261,196,324,983,415,34,2633,870,122,2075,772,1179,1243,143,209,234,2026,2178,1182,2080,176,828,1119,2546,1247,1890,1845,878,2845,366,1121,76,82,598,265,6,2084,1315,1852,886,742,931,2511,1793,1731,693,1733,1322,1000,1937,1323,1939,479,424,568,1736,1077,1861,570,938,1942,2184,348,2093,841,1011,2448,943,1270,269,2418,1138,2188,2619,10,2194,2796,519,755,2333,1506,1751,1348,1153,1818,2243,189,762,57,214,2840,526,128,1963,805,80,2206,2920,2594,485,1403,1290,319,61,1763 -0.3743938386878874,0.28459191556669194,0.9027628846125711,0.704699791414857,0.24801958368154803,1.5705949318057502,0.49884576098804173,1.0307485270519672,0.704699791414857,0.7382358716884349,0.5683656165997513,-1.5718746398609995,-1.0323962561974658,0.1367560507410777,0.24801958368154803,-0.13234464502495924,0.35698364577547,0.32091216739564127,0.02309828334687722,-1.9454153738987696,-1.2709592380232988,-0.6279701240574134,1.1864283685836194,0.9350551147231273,0.32091216739564127,0.8046697182564764,2.871469999732692,-1.0792715109109947,0.3928095936133701,1.5420358124097335,-0.4575872142200032,0.463737560425262,0.2111917997668451,0.17410512476192191,1.4261935465788533,1.155663166669387,1.0935808714347506,-0.4158281796670899,-0.5420991063561916,0.2111917997668451,-0.4575872142200032,1.2776448956782354,0.428393191730484,0.24801958368154803,-0.9398534966833773,0.17410512476192191,-0.29248013870191797,-0.2519914877556342,0.3928095936133701,-1.7288348009106087,0.8702695242261951,0.24801958368154803,1.9281348523770536,1.8747212260962505,0.6027831121744145,1.0307485270519672,4.496753993926139,-0.4575872142200032,0.1367560507410777,-0.2519914877556342,0.3928095936133701,0.49884576098804173,0.35698364577547,-0.8941728675715074,-0.21180894066884262,-0.1719280959561597,0.5337207971688037,-0.1719280959561597,0.1367560507410777,0.32091216739564127,-0.33327939055474815,0.1367560507410777,-0.33327939055474815,0.7382358716884349,0.8046697182564764,0.6369761233848037,-0.1719280959561597,0.28459191556669194,-0.2519914877556342,0.6369761233848037,0.35698364577547,-0.33327939055474815,-0.5420991063561916,0.9027628846125711,-0.4575872142200032,0.428393191730484,0.32091216739564127,-0.8039614683338043,0.35698364577547,0.17410512476192191,1.0307485270519672,-0.759418488288081,0.24801958368154803,-0.5420991063561916,-1.0323962561974658,4.351275402719301,-0.5420991063561916,-1.469700408349865,0.704699791414857,0.49884576098804173,-0.6714285051358926,0.02309828334687722,-0.1719280959561597,0.1367560507410777,0.24801958368154803,-0.21180894066884262,-0.5848621144923504,1.2474172170623723,0.49884576098804173,2.161837222901003,1.155663166669387,-1.6760094336606017,0.704699791414857,1.5420358124097335,-0.33327939055474815,0.463737560425262,1.901497527876068,-0.5420991063561916,-2.714784907553634,-0.9859257988083908,0.7382358716884349,0.09914099907683403,0.17410512476192191,0.9671485853633185,2.1108177774831414,-0.1719280959561597 2937 Regulation of endothelial cell migration 8 24 2.477709709674751 0.0132228677743611 P09601,P42785,Q8WTV0,P06576,P06744,P09429,P19174,O14786 Processes and pathways GO Biological process msigdb_gobp 34,6,10,196,324,415,234,118 486,118,2814,1114,1473,196,324,415,34,2075,772,234,2178,2080,2546,6,1852,931,1731,1077,1861,1011,10,1963 0.704699791414857,1.5705949318057502,-1.5718746398609995,0.24801958368154803,0.02309828334687722,1.1864283685836194,0.9350551147231273,0.8046697182564764,2.871469999732692,-0.4575872142200032,0.463737560425262,1.0935808714347506,-0.5420991063561916,-0.4575872142200032,-0.9398534966833773,4.496753993926139,-0.2519914877556342,0.35698364577547,-0.1719280959561597,0.28459191556669194,-0.2519914877556342,0.32091216739564127,4.351275402719301,-0.33327939055474815 2937