term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Intrinsic component of organelle membrane 84 124 7.48815852099751 6.984663702273456e-14 Q9Y2R0,O60830,P98194,Q8WVX9,O96008,Q99595,Q16611,Q96NB2,Q13505,Q5J8M3,Q00325,Q9NZ01,Q9NQC3,O60499,Q15070,O75844,Q8N2H4,P13473,O75431,Q8TCT9,P17152,Q9H9B4,Q8TB61,O14925,P42892,Q15629,Q9Y282,O95470,Q15125,Q9BUN8,Q7L0J3,Q03518,Q6P4A7,Q86YN1,Q96A33,O43819,Q9Y4P3,Q9P035,Q14739,Q9BUR5,Q8IWA4,P57105,Q12981,Q15388,Q9H3K2,Q9NPA0,O76024,P57088,P12235,Q5XKP0,O43505,P04439,Q9Y512,P20020,Q9GZY8,Q9BPX6,P27824,Q16891,Q9HC21,P51572,Q86XL3,L0R6Q1,Q6UXV4,O15258,Q5SNT2,Q6ZRP7,Q9H490,Q9UM00,Q53H12,O75880,Q9UBM7,Q9NVH1,O00767,Q99442,Q86Y82,O43808,Q9BTV4,Q9NX63,Q96K12,Q92643,O15126,Q9BWH2,Q9UH99,P10321 Localization GO Cellular component msigdb_gocc 4,5,522,524,525,19,544,546,36,550,554,556,59,63,65,67,69,72,583,80,592,601,89,92,100,114,119,128,131,147,149,152,166,171,174,175,183,203,210,213,218,222,223,232,234,239,247,255,259,260,262,275,290,291,299,301,311,318,319,327,335,337,352,355,356,362,366,385,387,395,400,408,416,432,442,444,460,461,469,468,463,479,497,499 666,337,416,92,2033,463,355,262,444,175,63,5,583,67,395,247,1152,690,769,128,525,1304,275,499,259,72,592,291,1679,2185,311,2037,2465,100,2374,923,890,327,2375,255,222,1130,941,522,554,152,605,223,36,2018,210,893,65,131,771,232,114,821,544,2326,318,387,550,356,260,166,352,362,149,733,335,442,171,218,969,1137,69,909,989,724,89,80,524,468,1401,881,174,469,546,663,432,19,301,1026,460,147,213,479,299,234,366,601,1512,319,726,239,59,2448,408,461,556,203,1170,1353,400,1406,497,385,119,4,183,677,290,1439 0.6194206088649225,1.2359622824697312,1.0416622545332883,2.2109109040904884,-0.3409024311136362,0.9543830980982788,1.1964900873490003,1.4845046522176364,0.9765264378161742,1.8185362415383943,2.346058243177083,3.1165747016179965,0.7568588077238091,2.329750012077,1.1049253152266847,1.5358542924197818,0.1684982022009186,0.5805078633245453,0.48718206135466036,2.0894866813375814,0.8751148153965543,0.07415070895816572,1.4495286247621895,0.9094287765563077,1.5017677751833673,2.291063262623579,0.7446925671515504,1.3959088234962316,-0.14270834812699967,-0.43590826117893794,1.3221664240422288,-0.3409024311136362,-0.6153848387722859,2.181344630255124,-0.5543007948494578,0.3329162614491058,0.36168996784734275,1.2650915011001496,-0.5543007948494578,1.510343999684222,1.6266810625618235,0.1838925440088085,0.3184040786732402,0.8866106862369233,0.8167483885125356,1.9386564503168657,0.7201675789757652,1.6266810625618235,2.596136262438205,-0.32228307221127694,1.6979807301199143,0.36168996784734275,2.3406400045953175,2.070521741578072,0.48718206135466036,1.6023224295792171,2.1390803803002107,0.4321969562595515,0.8402742865808962,-0.51428752530657,1.293823383957412,1.125611440557737,0.8285415486462114,1.1964900873490003,1.5017677751833673,1.8760367688861144,1.2064269794639189,1.1865067348823226,1.952285648216789,0.5409522516865753,1.2457167051043052,0.9875161701203701,1.8330785657592543,1.6586937760640963,0.30380731745916084,0.1838925440088085,2.31327983578579,0.34734463722339803,0.2891251966313216,0.5542099181825546,2.2225958317358057,2.2457277457630314,0.8866106862369233,0.9543830980982788,0.02566161901174243,0.3759530057373177,1.825821535867474,0.9543830980982788,0.8402742865808962,0.6322515068949177,1.0093338760985888,2.8113998714497686,1.350128868152097,0.25950170179577764,0.9654822230844401,1.9658133945446885,1.682361685022864,0.9432286304255554,1.38683389940539,1.6023224295792171,1.176476578042439,0.7324623353077244,-0.04041324981336907,1.293823383957412,0.5542099181825546,1.5776579775269348,2.3887739794503915,-0.5948794930148794,1.0629537868319574,0.9654822230844401,0.8167483885125356,1.7288431475403072,0.1684982022009186,0.05808732403364699,1.0840404415884148,0.02566161901174243,0.9207519138862322,1.1358809033740525,2.1268132851345656,3.129385678191442,1.7965090219596693,0.6194206088649225,1.4049437781239236,0.009297339019232754 3193 Transporter activity 102 161 6.499382200074008 8.065052520935047e-11 O60830,Q9UDW1,Q9H2D1,P98194,Q9C0H2,Q9NS69,O43676,O96008,Q99595,O75306,Q96NB2,Q00325,P06576,Q13423,O43681,P55011,O75964,P45880,Q9UGP8,P21796,P04062,O15173,Q9UBX3,Q14849,Q15758,Q70HW3,P17900,Q9H936,P24539,Q9H9B4,Q8TAD4,Q9Y487,Q8TB61,O14925,P11166,P56134,P13073,Q7KZN9,Q9HD20,Q9HC07,Q9P0J0,Q8NBU5,Q9Y277,Q02978,Q8WTV0,Q96ES6,Q7Z3C6,P51970,Q7L0J3,Q03518,Q9H2V7,Q96GC9,P38435,P08574,Q9BSK2,Q6P4A7,Q9UJS0,P08183,P12236,Q9Y6M7,O95202,O43772,P00403,P16615,Q9BQT8,P30536,Q93050,Q9NW15,Q15388,Q15043,Q8IXU6,Q6P4Q7,P12235,Q9Y619,Q8NE01,P05141,P20020,P56385,P49755,Q9HC21,L0R6Q1,O75746,Q99797,P05023,Q99808,P51798,Q9UM00,O75027,Q96S66,O95168,P53985,Q14728,P08195,Q6NUK1,Q9BXP2,P53007,O43808,P28288,Q9Y5J9,Q8TDW0,Q9BVC6,P61916 Functions GO Molecular function msigdb_gomf 5,6,7,522,11,10,16,525,19,543,546,554,552,43,557,558,47,48,571,51,53,56,57,58,565,77,79,593,83,601,86,88,89,92,612,618,109,112,113,116,129,647,135,644,141,142,660,656,149,152,155,156,157,668,162,166,169,176,179,189,190,191,195,196,197,200,208,220,232,241,246,254,259,267,280,284,291,305,304,319,337,350,359,363,372,383,385,397,403,404,407,411,417,419,433,440,444,473,488,484,495,491 337,2540,3036,832,2346,92,2033,56,16,557,191,444,5,397,876,543,958,1557,350,1281,47,1152,404,1963,190,847,525,195,53,363,1676,284,552,1522,1387,176,417,668,2722,1153,612,259,179,109,196,79,3040,291,981,693,2547,51,2309,83,1333,473,2959,200,1284,833,983,962,157,2998,866,48,679,2932,1602,304,3049,3161,383,656,1336,1767,440,407,558,618,305,1361,941,491,522,554,1605,644,152,43,2321,411,2117,58,241,232,565,1507,1002,3026,419,1209,166,254,77,112,149,660,246,647,280,724,86,89,484,141,1400,208,142,156,546,403,1116,19,359,372,883,197,162,495,433,826,1324,11,859,7,705,155,593,601,116,319,113,2448,10,220,129,57,6,571,2151,169,385,1276,135,88,488,267,2211,189,935 1.2359622824697312,-0.6777844648834328,-1.4118743308181245,0.4182557487269513,-0.5342242617338631,2.2109109040904884,-0.3409024311136362,2.39928112695771,2.850934877568107,0.8048943132507087,1.7592151429408447,0.9765264378161742,3.1165747016179965,1.0945079100252835,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.2064269794639189,0.09011573382996567,2.515439795372476,0.1684982022009186,1.0629537868319574,-0.303787854117314,1.7667329517528663,0.4042351666901161,0.8751148153965543,1.751667447018552,2.4355304023078563,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.8167483885125356,-0.05719278632694883,0.02566161901174243,1.8112225085127378,1.0416622545332883,0.6194206088649225,-0.8509667351664257,0.1684982022009186,0.7078077588474234,1.5017677751833673,1.803880161059405,2.1512615372917634,1.751667447018552,2.2457277457630314,-1.4118743308181245,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,2.5007588066882245,-0.51428752530657,2.2399742438327923,0.05808732403364699,0.9432286304255554,-1.2051532199617174,1.7364816398521126,0.09011573382996567,0.4182557487269513,0.2891251966313216,0.30380731745916084,1.9041316359550924,-1.3068387009445777,0.39013449402256833,2.515439795372476,0.6065201023101452,-1.1555145615983378,-0.09107218097239303,1.3408498426869389,-1.4386772460322241,-2.3972018839891502,1.1358809033740525,0.6322515068949177,0.05808732403364699,-0.1953518618147444,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.9207519138862322,0.8866106862369233,0.8167483885125356,-0.09107218097239303,0.6450133877649504,1.9386564503168657,2.5443983795118403,-0.51428752530657,1.05233382643295,-0.3785188752723304,2.394036011434074,1.5693674826960398,1.6023224295792171,0.7929788244184839,-0.04041324981336907,0.27435692511880505,-1.3589269339837995,1.0416622545332883,0.1374300649717309,1.8760367688861144,1.5188836640650665,2.2514617717609795,2.1451816415421097,1.952285648216789,0.6322515068949177,1.5442857407745552,0.6450133877649504,1.4406894094750298,0.5542099181825546,2.2342011612850494,2.2225958317358057,0.9320183829658302,1.9991966569128934,0.02566161901174243,1.7057429944746445,1.992569263975948,1.9180197862656285,0.8402742865808962,1.0735225288658525,0.19919490676105286,2.8113998714497686,1.1964900873490003,1.1663992693165688,0.3759530057373177,1.751667447018552,1.8971479790749635,0.9207519138862322,1.0093338760985888,0.4321969562595515,0.07415070895816572,2.984818292512709,0.4042351666901161,3.043830354362099,0.5805078633245453,1.9249245939305628,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,-0.5948794930148794,3.0024397548003465,1.6427531946624607,2.0831876730587275,2.39928112695771,3.1003852237037637,0.7929788244184839,-0.39751866108604983,1.854681789652418,1.1358809033740525,0.1059833465335269,2.051351117777622,2.2284083926639537,0.9320183829658302,1.4758172511688186,-0.43590826117893794,1.7742210599427393,0.3329162614491058 3193 Ion transmembrane transporter activity 63 99 5.986107147783464 2.149228130516861e-09 Q9UM00,P12235,Q9UDW1,Q9H2D1,Q9Y277,P98194,Q9C0H2,Q9Y619,Q96ES6,Q96S66,P53985,P05141,Q14728,P08195,Q96NB2,P20020,Q6NUK1,Q6P4A7,Q00325,Q9UJS0,P06576,Q13423,O43681,P55011,O75964,P45880,Q9BXP2,P56385,P21796,P12236,Q15758,Q9UBX3,P53007,Q9Y6M7,O95202,O43772,Q9HC21,O43808,P00403,P16615,Q9BQT8,Q70HW3,Q93050,Q9H936,P24539,Q9H9B4,Q8TAD4,Q9Y487,Q8TB61,Q9NW15,O75746,Q8TDW0,P11166,P13073,Q9BVC6,P05023,Q7KZN9,Q9HD20,Q15043,Q9HC07,Q99808,Q6P4Q7,P51798 Functions GO Molecular function msigdb_gomf 385,259,6,7,135,522,11,267,142,403,407,284,411,417,546,291,419,166,554,169,552,43,557,558,47,48,433,305,51,179,565,57,440,189,190,191,319,444,195,196,197,77,208,593,83,601,86,88,89,220,350,484,612,109,495,363,112,113,241,116,372,254,383 3036,2346,557,191,444,350,1281,47,190,195,363,1676,284,552,1522,1387,417,668,2722,1153,612,259,179,109,196,291,981,693,2547,51,83,1333,1284,833,983,962,2998,866,48,679,2932,3161,383,440,407,558,618,305,1361,941,522,554,1605,644,43,411,2117,241,565,3026,419,1209,166,254,77,112,724,86,89,484,1400,208,142,546,403,372,197,495,433,11,859,7,705,593,601,116,319,113,220,57,6,2151,169,385,135,88,267,2211,189 -1.4118743308181245,-0.5342242617338631,0.8048943132507087,1.7592151429408447,0.9765264378161742,1.2064269794639189,0.09011573382996567,2.515439795372476,1.7667329517528663,1.751667447018552,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.8167483885125356,-0.05719278632694883,0.02566161901174243,1.0416622545332883,0.6194206088649225,-0.8509667351664257,0.1684982022009186,0.7078077588474234,1.5017677751833673,1.803880161059405,2.1512615372917634,1.751667447018552,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,2.5007588066882245,2.2399742438327923,0.05808732403364699,0.09011573382996567,0.4182557487269513,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.39013449402256833,2.515439795372476,0.6065201023101452,-1.1555145615983378,-2.3972018839891502,1.1358809033740525,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.8866106862369233,0.8167483885125356,-0.09107218097239303,0.6450133877649504,2.5443983795118403,1.05233382643295,-0.3785188752723304,1.5693674826960398,0.7929788244184839,-1.3589269339837995,1.0416622545332883,0.1374300649717309,1.8760367688861144,1.5188836640650665,2.2514617717609795,2.1451816415421097,0.5542099181825546,2.2342011612850494,2.2225958317358057,0.9320183829658302,0.02566161901174243,1.7057429944746445,1.992569263975948,0.8402742865808962,1.0735225288658525,1.1663992693165688,1.751667447018552,0.9207519138862322,1.0093338760985888,2.984818292512709,0.4042351666901161,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,1.6427531946624607,2.39928112695771,3.1003852237037637,-0.39751866108604983,1.854681789652418,1.1358809033740525,2.051351117777622,2.2284083926639537,1.4758172511688186,-0.43590826117893794,1.7742210599427393 3193 Transporter 92 182 5.976707015326703 2.276931604243267e-09 Q9BQE5,P24390,Q9H2D1,P98194,Q8TEX9,O96008,O43731,Q96NB2,Q9P2W9,Q00325,P06576,P55011,Q15758,Q9UBX3,Q15363,Q12907,O60499,Q15070,Q8N2H4,P13473,Q70HW3,P17900,O43760,Q9H936,P24539,Q9H9B4,Q8TAD4,Q9Y487,Q8TB61,Q9Y3B3,Q92973,P11166,Q9HC07,Q9HD45,P52292,Q96ES6,Q9Y6C9,Q9NZJ7,Q7L0J3,Q03518,Q9H2V7,Q9BSK2,Q9UJS0,P08183,P12236,Q9Y6M7,O95202,O43772,P16615,Q9BQT8,Q93050,P11279,O95249,Q15388,Q15043,Q8IXU6,Q13190,P12235,Q9Y619,P05141,P20020,P56385,P49755,Q9HC21,P51572,Q99805,O15400,Q92544,O75746,P05023,Q99808,Q14444,O75027,P53985,Q9BVK6,P08195,Q6NUK1,Q9UNK0,Q00765,Q9BXP2,Q86Y82,P53007,Q9UI14,P49257,O43808,O14653,Q8N1F7,Q12769,O95721,P28288,Q8NFH4,Q9Y3A6 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 1,2,7,522,528,525,26,546,39,554,552,558,565,57,61,574,63,65,69,72,77,79,78,593,83,601,86,88,89,95,616,612,116,117,138,142,143,148,149,152,155,162,169,176,179,189,190,191,196,197,208,206,229,232,241,246,253,259,267,284,291,305,304,319,327,343,345,353,350,363,372,392,397,407,415,417,419,429,431,433,442,440,452,447,444,462,477,474,472,473,494,498 2301,1383,1013,1280,1196,1151,2486,916,462,345,26,78,191,444,63,1175,2543,957,1961,397,1412,350,1281,2651,190,229,1647,2182,1521,472,525,363,1676,284,552,176,417,1677,612,206,259,179,72,196,79,291,693,2547,2,83,1333,473,1474,833,1156,983,1179,2998,866,1053,1602,447,304,327,1085,138,2404,440,2962,2659,1054,407,2604,1898,798,2080,558,2315,618,1038,305,1308,1361,941,1390,2407,522,554,2589,431,644,152,2116,964,474,1424,574,253,2265,1537,392,2167,241,65,1505,2779,61,232,565,3026,419,1209,77,149,945,442,246,477,69,494,86,1005,89,1139,528,2333,734,353,616,208,636,1063,1723,142,1064,546,949,2361,1116,343,372,1,197,3018,162,2805,415,433,859,1881,7,705,155,593,601,116,319,117,2448,148,2674,1493,1298,39,2101,2175,57,2151,452,1590,169,429,1171,1673,498,95,88,754,267,1220,143,189 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3193 Organelle inner membrane 119 224 5.599213521894076 2.153264489232236e-08 Q567V2,Q9Y2R0,O60830,Q9UDW1,Q9H2D1,P82933,Q9NX14,O43676,P14406,O96008,Q99595,Q69YU5,Q9UDX5,O75306,Q96NB2,Q13505,O14949,Q00325,P06576,P21912,Q13423,O75964,Q99720,Q9UBX3,O75208,Q96CU9,Q9UJZ1,Q15070,O75844,Q9H061,Q9H1E5,Q70HW3,O75431,P17152,Q9H936,P24539,Q9Y5L4,Q9H9B4,P22830,O14925,P22695,P56134,P13073,Q7KZN9,Q96IX5,P40939,Q3ZCQ8,Q9P0J0,Q8N183,Q02978,Q9Y6C9,P51970,P09669,Q9Y4W6,Q9H2V7,P08574,Q9BSK2,Q6P4A7,P47985,Q03252,Q9UJS0,P23786,O43819,P12236,Q9BZE1,O95202,O43772,P00403,Q9BRT2,Q9BQT8,O94901,Q9NPL8,Q14739,Q8NE86,Q9BUR5,Q6DKK2,O60313,Q9H3K2,Q10713,P12235,Q5XKP0,P50402,Q9Y619,Q9NVI7,P05141,Q8NBN7,Q9Y512,Q9BRJ2,Q9BPX6,P56385,Q5T9A4,P53701,Q16891,Q9HC21,Q96TA2,O75746,Q6UXV4,Q5SNT2,Q8WWC4,Q6PI78,O43615,O95674,Q53H12,Q99623,O95831,O75880,O75027,O95168,Q9NVH1,Q14728,Q6NUK1,Q8IYU8,P53007,P49748,Q9BTV4,Q9NX63,Q7Z7H8,Q9Y5J9,Q9UH99 Localization GO Cellular component msigdb_gocc 3,4,5,6,7,521,530,16,18,525,19,22,28,543,546,36,37,554,552,553,43,47,50,57,563,60,577,65,67,68,75,77,583,592,593,83,602,601,596,92,97,618,109,112,637,631,639,129,641,644,143,656,652,677,155,668,162,166,679,680,169,167,175,179,704,190,191,195,712,197,690,727,210,724,213,219,221,234,236,259,260,261,267,277,284,287,290,302,301,305,309,317,318,319,348,350,352,356,357,375,376,377,387,388,389,395,397,404,408,411,419,425,440,455,460,461,466,488,497 2540,832,92,37,376,16,191,175,221,5,397,563,876,543,958,583,2072,1557,739,350,67,395,1281,47,1106,690,404,1963,190,847,377,389,525,195,284,552,3108,668,2183,1622,652,1153,2458,259,179,2740,109,18,770,922,592,960,3040,981,719,553,2704,97,596,1969,167,83,1333,2959,1795,1284,2355,786,983,1032,2465,631,1034,1108,1052,679,2932,1001,455,3049,2374,261,1531,656,1183,440,317,1088,2218,618,305,1337,892,1421,1339,2410,1533,1340,1310,521,554,644,680,236,1133,1363,1312,1574,43,36,943,411,210,65,821,1507,1002,318,639,387,3,1161,356,895,309,260,22,219,419,790,166,375,809,352,77,112,2231,466,425,641,1097,1719,2121,287,989,1545,724,1907,357,1238,856,1212,948,60,2567,776,637,546,348,19,388,50,301,812,197,302,712,162,1117,460,2242,213,800,972,1726,1243,704,68,75,7,155,802,234,931,593,601,2824,1512,1327,319,727,2448,1374,408,277,530,461,1377,1514,1848,129,861,57,6,28,497,169,577,862,1463,4,1782,912,2344,1551,1031,1409,677,290,488,602,267,143,935 -0.6777844648834328,0.4182557487269513,2.2109109040904884,2.58685650649295,1.1461017884280336,2.850934877568107,1.7592151429408447,1.8185362415383943,1.6266810625618235,3.1165747016179965,1.0945079100252835,0.7929788244184839,0.3759530057373177,0.8402742865808962,0.30380731745916084,0.7568588077238091,-0.3596472519831671,-0.07407874008591195,0.5276212788728801,1.2064269794639189,2.329750012077,1.1049253152266847,0.09011573382996567,2.515439795372476,0.19919490676105286,0.5805078633245453,1.0629537868319574,-0.303787854117314,1.7667329517528663,0.4042351666901161,1.1461017884280336,1.1152930343193794,0.8751148153965543,1.751667447018552,1.4228948856937176,0.8167483885125356,-1.719495047292511,0.6194206088649225,-0.43590826117893794,-0.1081741936250891,0.6322515068949177,0.1684982022009186,-0.6153848387722859,1.5017677751833673,1.803880161059405,-0.8733409382481655,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,0.7446925671515504,0.30380731745916084,-1.4118743308181245,0.2891251966313216,0.5542099181825546,0.8167483885125356,-0.8287583635800084,2.1932323689347277,0.7324623353077244,-0.303787854117314,1.8618274754931423,2.2399742438327923,0.05808732403364699,-1.2051532199617174,-0.213128942203161,0.09011573382996567,-0.5342242617338631,0.4735513630461408,0.2891251966313216,0.2445587153188426,-0.6153848387722859,0.6703324293561015,0.2445587153188426,0.19919490676105286,0.22952714396117282,0.6065201023101452,-1.1555145615983378,0.27435692511880505,0.9654822230844401,-1.4386772460322241,-0.5543007948494578,1.4931547427369818,-0.05719278632694883,0.6322515068949177,0.15301100508827867,0.9875161701203701,1.3033138565109923,0.21440615544338357,-0.4553008972742839,0.6953823294342337,1.3408498426869389,0.05808732403364699,0.36168996784734275,0.009297339019232754,0.05808732403364699,-0.5745186791895069,-0.05719278632694883,0.05808732403364699,0.07415070895816572,0.8866106862369233,0.8167483885125356,0.6450133877649504,0.6065201023101452,1.5859138151123813,0.1838925440088085,0.04192461851956566,0.07415070895816572,-0.07407874008591195,2.5443983795118403,2.596136262438205,0.3184040786732402,1.05233382643295,1.6979807301199143,2.3406400045953175,0.4321969562595515,-0.04041324981336907,0.27435692511880505,1.293823383957412,0.6577068359941382,1.125611440557737,3.17018189671295,0.1684982022009186,1.1964900873490003,0.36168996784734275,1.3315291268555391,1.5017677751833673,2.745828206525584,1.6427531946624607,1.0416622545332883,0.4735513630461408,1.8760367688861144,1.1562744576555442,0.44605949669078204,1.2064269794639189,2.2514617717609795,2.1451816415421097,-0.4553008972742839,0.9543830980982788,1.0201626829533696,0.6577068359941382,0.21440615544338357,-0.16014273539632354,-0.3785188752723304,1.413939040620315,0.2891251966313216,-0.05719278632694883,0.5542099181825546,-0.2671646500903092,1.1964900873490003,0.12175448251162654,0.4042351666901161,0.1374300649717309,0.3184040786732402,2.356841664788679,-0.6777844648834328,0.48718206135466036,0.6703324293561015,0.8402742865808962,1.216317751801572,2.8113998714497686,1.125611440557737,2.5056676046326203,1.350128868152097,0.44605949669078204,1.751667447018552,1.350128868152097,0.5673949130081869,1.8971479790749635,0.19919490676105286,0.9654822230844401,-0.4553008972742839,1.682361685022864,0.45984406883424556,0.30380731745916084,-0.16014273539632354,0.12175448251162654,0.5805078633245453,2.329750012077,2.2628718108903665,3.043830354362099,1.9249245939305628,0.45984406883424556,1.6023224295792171,0.3329162614491058,0.7446925671515504,0.7324623353077244,-0.9645358333127365,-0.04041324981336907,0.07415070895816572,1.293823383957412,0.5542099181825546,-0.5948794930148794,0.04192461851956566,1.0629537868319574,1.4495286247621895,0.8751148153965543,0.9654822230844401,0.04192461851956566,-0.04041324981336907,-0.23102262249362931,2.0831876730587275,0.4042351666901161,2.39928112695771,3.1003852237037637,2.6684245539590274,0.9207519138862322,1.854681789652418,0.7810014179820873,0.4042351666901161,-0.007169221259632773,3.129385678191442,-0.1953518618147444,0.34734463722339803,-0.51428752530657,-0.05719278632694883,0.25950170179577764,0.02566161901174243,0.6194206088649225,1.4049437781239236,0.9320183829658302,0.7324623353077244,1.4758172511688186,1.992569263975948,0.3329162614491058 3193 Outer membrane 49 93 5.576660974512137 2.451790334898609e-08 Q96TC7,O00264,Q53H12,Q5XKP0,P50402,Q99623,Q9Y277,Q9NS69,Q9UBM7,Q8N4H5,Q9Y6C9,P09601,O96008,Q9NZJ7,Q8WY22,Q9NVH1,O43169,Q9HCL2,Q16611,Q9Y512,Q9NQZ5,Q13505,Q9GZY8,Q8N2A8,P45880,Q96RL7,Q99720,P21796,O00165,P52789,Q9NZ45,Q8WXH0,Q9NVT9,Q16891,Q8NAN2,P30536,Q9NX63,Q6NUM9,Q9BUR5,Q8IWA4,Q9BWH2,O60313,P57105,Q6UXV4,Q9Y371,Q15388,Q9UBF8,Q9BVC6,P42345 Localization GO Cellular component msigdb_gocc 384,258,387,260,261,388,135,10,400,15,143,17,525,148,23,408,25,281,544,290,163,36,299,559,48,178,50,51,303,435,54,575,576,318,457,200,461,207,213,218,479,221,222,352,487,232,496,495,500 303,258,1249,3169,25,221,1555,1222,583,1152,769,1048,525,888,3095,1622,17,2252,51,200,1202,2465,500,1034,48,261,923,435,2218,222,1337,2747,36,1807,1288,232,2168,544,318,387,2019,260,207,1396,352,1905,218,969,1137,1811,559,15,1269,457,647,575,23,1239,881,2127,1190,178,384,1295,388,50,2201,213,495,479,299,2806,281,2595,1244,163,10,842,1328,408,576,2027,461,753,54,148,496,400,1406,135,487,290,143 1.3408498426869389,1.5017677751833673,0.1059833465335269,-2.6169954275388214,2.6859731952221364,1.6266810625618235,-0.07407874008591195,0.12175448251162654,0.7568588077238091,0.1684982022009186,0.48718206135466036,0.22952714396117282,0.8751148153965543,0.36168996784734275,-1.6327200595968123,-0.1081741936250891,2.850934877568107,-0.4748273403029004,2.5007588066882245,1.7364816398521126,0.1374300649717309,-0.6153848387722859,0.9094287765563077,0.2445587153188426,2.515439795372476,1.4931547427369818,0.3329162614491058,0.9984518432806867,-0.4553008972742839,1.6266810625618235,0.05808732403364699,-0.8733409382481655,2.596136262438205,-0.213128942203161,0.09011573382996567,1.6023224295792171,-0.41664798954862137,0.8402742865808962,1.293823383957412,1.125611440557737,-0.32228307221127694,1.5017677751833673,1.7057429944746445,0.02566161901174243,1.2064269794639189,-0.2671646500903092,1.6586937760640963,0.30380731745916084,0.1838925440088085,-0.213128942203161,0.8048943132507087,2.9120109684113684,0.1059833465335269,0.9654822230844401,0.6450133877649504,0.7810014179820873,2.7332025048093493,0.12175448251162654,0.3759530057373177,-0.3785188752723304,0.15301100508827867,1.8112225085127378,1.1358809033740525,0.09011573382996567,1.125611440557737,2.5056676046326203,-0.43590826117893794,1.682361685022864,0.9207519138862322,0.9432286304255554,1.38683389940539,-0.9414783391764264,1.4406894094750298,-0.6988844633124501,0.12175448251162654,1.8971479790749635,3.0024397548003465,0.4182557487269513,0.07415070895816572,1.0629537868319574,0.7810014179820873,-0.32228307221127694,0.9654822230844401,0.5142163574940924,2.430401334304574,1.9590621281540601,0.9207519138862322,1.0840404415884148,0.02566161901174243,2.051351117777622,0.9320183829658302,1.4049437781239236,1.992569263975948 3193 Nuclear outer membrane endoplasmic reticulum membrane network 157 285 5.531682110009157 3.171743339399654e-08 P43307,Q9BQE5,P24390,Q13724,P51571,P61019,Q14108,Q9Y394,P09601,O43731,O95197,Q8N0U8,P30519,Q5J8M3,Q9P2W9,Q9NZ01,O75915,Q96CS3,Q99720,Q9UGP8,Q14849,O14880,Q8WXH0,Q15363,Q9NQC3,Q12907,O75844,P51648,Q07065,Q8TCT9,Q15392,Q7Z2K6,O60725,Q8TB61,Q10471,P67812,Q9Y3B3,P37268,Q86UE4,Q5JRA6,Q15800,Q9Y5M8,Q06136,Q9BV10,Q9HD20,Q15629,Q8NFQ8,Q12959,Q96G23,Q9Y282,Q96KC8,Q8IY17,O95470,Q70UQ0,Q15125,P52292,P61803,Q9H0U4,Q96S52,Q5BJF2,O94874,Q7Z3C6,Q9BUN8,Q03518,A1L0T0,Q96GC9,P38435,Q9NZ08,Q8N511,Q9BRR6,Q16850,Q86YN1,Q96A33,Q96RL7,Q5VUD6,Q96PC5,Q8NF37,Q9Y4P3,Q8IV08,P35613,P16615,Q9UBV2,Q9P035,P46977,Q6NUM9,P04035,Q14739,Q969V3,Q9BUR5,Q12981,Q9NPA0,O75845,Q6NUQ4,O15260,O76024,P16435,O15269,Q13190,P57088,O00264,P50402,Q9UKR5,Q8NHH9,P62942,P04439,Q8N5M9,Q8WVQ1,Q53GQ0,Q92604,Q14534,Q99640,P49755,P27824,Q2TAA5,Q99735,O43852,Q9UBU6,Q15005,Q15904,Q96HY6,Q9H3N1,P51572,P07099,Q86UL3,Q86XL3,Q9BT22,Q8NHP6,Q9H490,Q8N2K0,P49458,O95674,Q9UM00,Q9UBM7,Q96S66,Q9BVK6,P35610,O00767,Q9Y320,P61026,Q99442,Q6UWP7,P49257,Q96AG4,Q92643,Q8TCJ2,O14653,Q9NTJ5,Q9BU23,Q8TDW0,Q6NUQ1,O95864,Q9Y3A6,Q9UBF8,Q9BVC6,P04843,P42345,P10321 Localization GO Cellular component msigdb_gocc 0,1,2,511,519,520,9,531,17,26,27,30,32,550,39,556,551,560,50,571,58,562,575,61,59,574,67,71,73,80,84,600,87,89,605,94,95,99,102,613,107,108,110,111,113,114,626,625,118,119,125,640,128,130,131,138,658,664,663,144,651,660,147,152,153,156,157,159,161,164,170,171,174,178,177,180,181,183,184,192,196,198,203,204,207,205,210,212,213,223,239,238,243,245,247,248,252,253,255,258,261,266,271,276,275,279,283,286,289,297,298,304,311,312,314,315,320,322,323,326,329,327,331,334,335,342,340,366,371,374,377,385,400,403,415,410,416,423,430,432,441,447,458,468,467,462,486,485,484,483,482,498,496,495,490,500,499 666,153,844,258,1249,2134,416,2486,462,562,1104,2032,715,245,252,1198,2542,716,26,315,1125,1555,1705,87,756,2424,903,67,238,551,247,651,2036,1015,2073,2651,27,1647,128,2182,1521,1048,377,482,2878,888,1304,205,275,490,815,785,3095,331,2005,1927,17,499,1443,248,196,960,1445,2309,3066,2,1932,2185,311,2907,2037,32,3091,2464,1202,1156,410,192,99,157,1448,500,1034,0,204,1053,655,685,1602,447,374,304,1037,261,519,327,71,1085,138,2962,2659,2604,2584,2315,255,2899,2376,2163,1655,520,430,1055,1680,941,658,1390,1337,1263,2813,276,2934,94,2358,1534,152,1607,110,73,605,1452,574,625,223,253,1425,2381,511,9,880,2018,868,297,210,58,322,893,752,1937,131,61,986,84,2294,1632,114,788,107,323,2326,170,312,286,144,550,613,177,743,207,483,243,1209,441,130,600,660,102,334,733,335,171,184,2330,640,30,371,161,1269,279,909,181,626,271,340,2273,89,896,467,2021,80,871,484,1139,734,283,575,1211,289,468,2611,1401,212,174,458,560,118,156,898,326,125,180,178,663,403,432,298,50,314,1,164,858,1026,342,485,147,213,111,495,2770,415,826,1324,859,664,930,329,366,932,827,726,113,860,239,59,486,842,753,556,159,203,1170,1493,1353,39,2101,496,400,320,198,571,266,3183,385,2479,119,423,531,498,95,2995,183,754,108,3159,1220,1439 0.6194206088649225,1.9318034306318732,0.4042351666901161,1.5017677751833673,0.1059833465335269,-0.39751866108604983,1.0416622545332883,-0.6360363435663436,0.9543830980982788,0.7929788244184839,0.19919490676105286,-0.3409024311136362,0.5542099181825546,1.5442857407745552,1.5188836640650665,0.1374300649717309,-0.6777844648834328,0.5542099181825546,2.6816050945494077,1.3033138565109923,0.1838925440088085,-0.07407874008591195,-0.16014273539632354,2.2284083926639537,0.5007368375870117,-0.5948794930148794,0.34734463722339803,2.329750012077,1.5776579775269348,0.8167483885125356,1.5358542924197818,0.6322515068949177,-0.3409024311136362,0.25950170179577764,-0.3596472519831671,-0.7848314137948916,2.6684245539590274,-0.12538587769838372,2.0894866813375814,-0.43590826117893794,-0.05719278632694883,0.22952714396117282,1.1461017884280336,0.9320183829658302,-1.0585470825916556,0.36168996784734275,0.07415070895816572,1.7057429944746445,1.4495286247621895,0.9207519138862322,0.4321969562595515,0.4735513630461408,-1.6327200595968123,1.2457167051043052,-0.32228307221127694,-0.28541547461577405,2.850934877568107,0.9094287765563077,-0.007169221259632773,1.5358542924197818,1.751667447018552,0.30380731745916084,-0.007169221259632773,-0.51428752530657,-1.492956015355766,3.21572160468917,-0.28541547461577405,-0.43590826117893794,1.3221664240422288,-1.1066521830470757,-0.3409024311136362,2.637217657100284,-1.6042899045333228,-0.6153848387722859,0.1374300649717309,0.1684982022009186,1.05233382643295,1.7592151429408447,2.1872987787678158,1.9041316359550924,-0.007169221259632773,0.9094287765563077,0.2445587153188426,3.2740327620941194,1.7211740059471201,0.22952714396117282,0.6322515068949177,0.5935493889180543,-0.09107218097239303,0.9765264378161742,1.1562744576555442,1.3408498426869389,0.2445587153188426,1.4931547427369818,0.8866106862369233,1.2650915011001496,2.2966451596705606,0.21440615544338357,2.0254641929604245,-1.2051532199617174,-0.7848314137948916,-0.7201373856155233,-0.6988844633124501,-0.51428752530657,1.510343999684222,-1.082506135737104,-0.5543007948494578,-0.41664798954862137,-0.12538587769838372,0.8866106862369233,1.0093338760985888,0.22952714396117282,-0.14270834812699967,0.3184040786732402,0.6322515068949177,0.02566161901174243,0.05808732403364699,0.1059833465335269,-0.9645358333127365,1.4495286247621895,-1.1555145615983378,2.1991455126433834,-0.5342242617338631,-0.05719278632694883,1.9386564503168657,-0.09107218097239303,2.1512615372917634,2.28546270022205,0.7201675789757652,-0.007169221259632773,0.7810014179820873,0.682890738977402,1.6266810625618235,1.5188836640650665,0.009297339019232754,-0.5543007948494578,0.8980485194817284,3.0232917146470886,0.3759530057373177,-0.32228307221127694,0.39013449402256833,1.38683389940539,1.6979807301199143,2.394036011434074,1.284289708677259,0.36168996784734275,0.5142163574940924,-0.28541547461577405,2.070521741578072,2.3514587661376916,0.2891251966313216,2.2399742438327923,-0.494489054305589,-0.1081741936250891,2.1390803803002107,0.4735513630461408,2.163357703140536,1.284289708677259,-0.51428752530657,1.8475085220023033,1.3221664240422288,1.413939040620315,1.9859173850366558,0.8285415486462114,0.7078077588474234,1.8112225085127378,0.5276212788728801,1.7057429944746445,0.9320183829658302,1.5610421002753638,0.1374300649717309,0.9875161701203701,2.0768660692333203,0.7324623353077244,0.6322515068949177,2.181344630255124,1.2457167051043052,0.5409522516865753,1.2457167051043052,1.8330785657592543,1.7891089124911725,-0.51428752530657,0.6577068359941382,2.650670416030812,1.1663992693165688,1.8971479790749635,0.1059833465335269,1.4406894094750298,0.34734463722339803,1.7965090219596693,0.682890738977402,1.4583294958454196,1.2359622824697312,-0.4748273403029004,2.2225958317358057,0.36168996784734275,0.9543830980982788,-0.32228307221127694,2.2457277457630314,0.39013449402256833,0.9320183829658302,0.1838925440088085,0.5409522516865753,1.4318115854602973,0.7810014179820873,0.1374300649717309,1.4049437781239236,0.9543830980982788,-0.7201373856155233,0.02566161901174243,1.682361685022864,1.825821535867474,0.9654822230844401,0.8048943132507087,2.1268132851345656,1.9180197862656285,0.36168996784734275,1.2747125192304771,2.1020174194592656,1.803880161059405,1.8112225085127378,0.6322515068949177,1.0735225288658525,1.0093338760985888,1.38683389940539,2.5056676046326203,1.3127614347392678,3.268320628293502,1.8901377227355411,0.4042351666901161,0.25950170179577764,1.2359622824697312,0.9320183829658302,1.9658133945446885,1.682361685022864,2.1512615372917634,0.9207519138862322,-0.8958829370602809,1.05233382643295,0.4321969562595515,0.07415070895816572,0.4042351666901161,0.6322515068949177,0.3329162614491058,1.2650915011001496,1.176476578042439,0.3329162614491058,0.4321969562595515,0.5542099181825546,2.1451816415421097,0.4042351666901161,1.5776579775269348,2.3887739794503915,0.9320183829658302,0.4182557487269513,0.5142163574940924,0.8167483885125356,1.9041316359550924,1.7288431475403072,0.1684982022009186,-0.023739075165896593,0.05808732403364699,2.572831939044648,-0.3596472519831671,0.9207519138862322,1.0840404415884148,1.293823383957412,1.751667447018552,0.7929788244184839,1.4758172511688186,-3.599840094441577,1.1358809033740525,-0.6153848387722859,2.1268132851345656,1.03093867386121,0.8751148153965543,0.9207519138862322,2.1991455126433834,-1.2811099242588615,1.7965090219596693,0.5142163574940924,2.163357703140536,-2.326770357792346,0.1374300649717309,0.009297339019232754 3193 Cation transmembrane transporter activity 46 67 5.1906891558806905 2.095171517484697e-07 Q9UM00,P12235,Q9UDW1,P98194,Q9Y619,Q96ES6,P05141,P08195,P08574,P20020,Q96NB2,Q00325,P47985,P06576,Q13423,P55011,O75964,Q9BXP2,P56385,Q9H2J7,Q15758,Q9Y6M7,O95202,Q9HC21,P21281,O43772,O43808,P00403,P16615,Q70HW3,Q93050,Q9H936,P24539,Q8TAD4,Q9H9B4,Q9Y487,Q9NW15,P56134,P13073,P05023,Q7KZN9,Q9HD20,Q15043,Q9HC07,Q99808,Q6P4Q7 Functions GO Molecular function msigdb_gomf 385,259,6,522,267,142,284,417,668,291,546,554,679,552,43,558,47,433,305,705,565,189,190,319,693,191,444,195,196,77,208,593,83,86,601,88,220,618,109,363,112,113,241,116,372,254 191,444,1281,47,190,195,363,1676,284,552,1522,1387,417,668,1153,259,109,196,291,981,693,2547,83,1333,1284,983,962,2998,679,2932,3161,558,618,305,1361,941,522,554,1605,43,241,565,254,77,112,724,86,1400,208,142,546,372,433,859,705,593,601,116,319,113,220,6,2151,385,88,267,189 1.7592151429408447,0.9765264378161742,0.09011573382996567,2.515439795372476,1.7667329517528663,1.751667447018552,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.8167483885125356,-0.05719278632694883,0.02566161901174243,1.0416622545332883,0.6194206088649225,0.1684982022009186,1.5017677751833673,2.1512615372917634,1.751667447018552,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,2.2399742438327923,0.05808732403364699,0.09011573382996567,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.6065201023101452,-1.1555145615983378,-2.3972018839891502,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.8866106862369233,0.8167483885125356,-0.09107218097239303,2.5443983795118403,1.5693674826960398,0.7929788244184839,1.5188836640650665,2.2514617717609795,2.1451816415421097,0.5542099181825546,2.2342011612850494,0.02566161901174243,1.7057429944746445,1.992569263975948,0.8402742865808962,1.1663992693165688,1.0093338760985888,0.4042351666901161,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,1.6427531946624607,3.1003852237037637,-0.39751866108604983,1.1358809033740525,2.2284083926639537,1.4758172511688186,1.7742210599427393 3193 Transmembrane transport 108 211 5.181149388646167 2.2052278359922698e-07 O60830,Q9UDW1,Q9H2D1,P98194,Q9C0H2,Q9NS69,O96008,Q16625,Q99595,Q16611,Q96NB2,P46934,Q00325,P06576,Q13423,O75915,P55011,O75964,P45880,Q9UGP8,P21796,P04062,P31751,Q9UBX3,Q15758,Q9UJZ1,O75844,Q70HW3,Q9H936,P24539,Q9H9B4,Q8TAD4,Q8TB61,O14925,P11166,P56134,Q9UHG3,P13073,Q7KZN9,Q9HD20,Q15629,Q9HC07,P27105,Q12959,P62258,Q9Y277,Q8WTV0,Q96ES6,Q7L0J3,Q03518,Q9H2V7,Q96GC9,P38435,Q9BSK2,Q6P4A7,P23786,Q9UJS0,P08183,P12236,Q9Y6M7,O95202,O43772,P00403,P16615,Q9BQT8,Q9NW15,Q15388,Q15043,Q8IXU6,Q6P4Q7,P12235,O75381,Q9Y619,P62942,Q8NE01,P05141,P20020,Q9BPX6,P56385,P49755,Q9HC21,L0R6Q1,O75746,Q8WWC4,Q99797,P05067,P05023,Q99808,O43615,P51798,Q9UM00,Q99623,O95831,O75027,P53985,Q14728,P08195,Q6NUK1,Q8IYU8,Q99442,Q9BXP2,P52789,P53007,O43808,P28288,Q8TDW0,Q9BVC6,O60831 Processes and pathways GO Biological process msigdb_gobp 5,6,7,522,11,10,525,532,19,544,546,35,554,552,43,551,558,47,48,571,51,53,564,57,565,577,67,77,593,83,601,86,89,92,612,618,105,109,112,113,114,116,115,625,633,135,141,142,149,152,155,156,157,162,166,167,169,176,179,189,190,191,195,196,197,220,232,241,246,254,259,263,267,276,280,284,291,301,305,304,319,337,350,357,359,360,363,372,376,383,385,388,389,397,407,411,417,419,425,432,433,435,440,444,473,484,495,489 337,1383,3036,832,2346,92,376,1076,191,444,1125,2488,5,489,397,2987,876,1222,263,2072,350,67,551,1281,47,1152,190,2426,389,525,195,53,363,1676,360,284,1078,1596,552,1522,2137,1414,1387,176,417,668,2722,1153,2458,612,1306,2403,259,179,109,196,1623,1501,291,981,693,2547,3065,51,167,83,1333,115,3117,473,2678,3091,564,1284,1202,833,983,962,157,2998,866,1081,48,35,1227,679,2932,304,2467,923,1181,3161,383,435,440,407,798,558,618,305,2899,2434,1361,941,633,276,2378,522,554,1605,644,152,2320,2887,1423,2193,2499,625,43,1453,2381,2412,411,2117,2225,241,2779,232,114,565,1940,544,532,1508,639,419,1209,166,254,2797,77,112,149,2798,2330,246,425,2838,928,1991,280,724,86,89,2021,484,141,357,1400,142,156,898,546,432,3151,19,388,359,372,2786,301,197,910,162,495,433,2276,826,11,859,801,7,705,155,593,601,1327,116,319,113,1147,735,2448,10,220,57,6,571,2478,105,2151,169,577,830,385,135,2481,677,267,2211,189 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3193 Organelle subcompartment 171 357 5.1317967062603005 2.869893780144141e-07 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Localization GO Cellular component msigdb_gocc 0,1,2,511,519,520,9,522,531,17,26,27,30,32,34,39,550,556,551,560,50,571,53,58,59,562,61,575,574,63,67,69,71,73,80,84,87,89,94,95,99,102,106,107,108,110,111,113,114,116,118,119,121,125,128,130,131,138,144,147,152,153,156,157,159,161,164,170,171,174,178,177,180,181,183,184,185,192,196,198,203,204,207,205,210,212,213,223,229,236,239,238,243,245,247,248,252,253,255,258,261,266,268,271,272,276,275,279,283,286,289,297,298,304,311,312,314,315,320,322,323,326,329,327,331,334,335,342,340,358,360,366,369,371,374,377,385,400,403,415,410,416,423,429,430,431,432,441,447,445,456,458,468,467,463,465,462,470,486,485,484,483,482,498,496,495,490,507,505,500,499 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3193 Transporters 181 359 5.111998011151691 3.187691840838613e-07 P24390,Q9H2D1,Q14108,P98194,Q9C0H2,O60637,Q8TEX9,O96008,P07602,Q16625,Q8WY22,P78310,Q16611,Q96NB2,P46934,Q5J8M3,Q00325,P21912,O75915,O43681,P55011,P45880,Q9NR77,Q99720,Q9UGP8,Q9UBX3,Q14849,Q15758,Q15363,Q15070,O75844,Q9H061,Q12834,P13473,Q07065,Q70HW3,O60826,O96005,Q9H936,Q8TAD4,Q9H9B4,Q8TB61,Q9Y3B3,O60443,Q5VW38,Q92973,Q5JRA6,P11166,O15127,P13073,Q9UPN3,Q9HD20,Q15629,Q9HC07,O60784,P27105,Q12959,Q96A57,Q96A65,O15504,Q8NE00,P52292,Q02978,P61803,Q8WTV0,Q9ULH0,Q9Y6C9,Q5BJF2,Q92621,Q9BUN8,Q9NZJ7,Q9BRK5,Q03518,Q9H2V7,Q96GC9,Q6ZXV5,Q8N511,Q9BSK2,Q9NQZ5,Q6P4A7,Q9UJS0,Q96A33,Q96RL7,P08183,P12236,Q96PC5,Q9Y6M7,O95202,O43772,P35613,P00403,P16615,Q9BQT8,Q9UBV2,P46977,Q93050,P04035,P11279,P02786,Q969V3,Q9BUR5,Q8IWA4,Q9NW15,O60313,P57105,Q9BTX1,Q96P70,Q9NPA0,Q15043,O15260,Q8IXU6,O76024,Q13190,Q6P4Q7,P57088,P12235,O75381,Q9Y619,Q8NHH9,P62942,P04439,Q8NE01,P05141,Q9Y512,P20020,Q9NUQ8,Q9BPX6,Q08722,P49755,Q16891,Q9HC21,Q9UBU6,Q15904,Q9H3N1,P51572,O75955,Q99805,Q9UHB9,Q92544,O75746,O15258,Q969E2,P05067,P05023,Q6UW68,Q99808,P49458,P51798,Q9UM00,P40855,O75027,Q8IY95,Q96S66,P53985,O95295,P08195,Q6NUK1,Q9Y320,Q8IYU8,Q99442,Q9BXP2,P53007,Q9UI14,P49257,O43808,Q96AG4,O15397,Q8TCJ2,O15126,Q8N1F7,Q12769,O14828,P28288,Q9Y371,Q8TDW0,Q8NFH4,Q9UH99,Q9BVC6,P04843,P61916,O60831 Functions Protein Atlas Protein class protein_atlas_protein_class 2,7,9,522,11,13,528,525,20,532,23,536,544,546,35,550,554,553,551,557,558,48,49,50,571,57,58,565,61,65,67,68,586,72,73,77,582,81,593,86,601,89,95,96,101,616,613,612,106,109,622,113,114,116,623,115,625,121,636,642,137,138,644,658,141,665,143,144,661,147,148,151,152,155,156,160,161,162,163,166,169,174,178,176,179,180,189,190,191,192,195,196,197,198,204,208,205,206,209,212,213,218,220,221,222,227,237,239,241,245,246,247,253,254,255,259,263,267,271,276,275,280,284,290,291,292,301,306,304,318,319,320,323,329,327,338,343,349,353,350,355,358,360,363,370,372,374,383,385,386,397,399,403,407,409,417,419,423,425,432,433,440,452,447,444,458,453,467,463,477,474,470,473,487,484,494,497,495,490,491,489 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3193 Ion transmembrane transport 79 154 5.1043785569413895 3.318833219466832e-07 Q9UDW1,Q9H2D1,P98194,Q9C0H2,Q16611,Q96NB2,P46934,Q00325,P06576,Q13423,O75915,P55011,O75964,P45880,P21796,Q15758,Q9UBX3,Q9UJZ1,O75844,Q70HW3,Q9H936,P24539,Q9H9B4,Q8TAD4,Q8TB61,Q9UHG3,P56134,P13073,Q7KZN9,Q9HD20,Q9HC07,P27105,Q12959,P62258,Q9Y277,Q02978,Q96ES6,Q9Y4W6,Q96GC9,P08574,Q6P4A7,Q9UJS0,P08183,P12236,Q9Y6M7,O95202,O43772,P00403,P16615,Q9BQT8,Q9NW15,Q15043,Q6P4Q7,P12235,Q9Y619,P62942,P05141,P20020,Q9BPX6,P56385,Q9HC21,O75746,Q8WWC4,P05067,P05023,P51798,Q9UM00,Q99623,O75027,P53985,Q14728,P08195,Q8IYU8,Q9BXP2,P53007,O43808,Q8TDW0,Q9BVC6,O60831 Processes and pathways GO Biological process msigdb_gobp 6,7,522,11,544,546,35,554,552,43,551,558,47,48,51,565,57,577,67,77,593,83,601,86,89,105,618,109,112,113,116,115,625,633,135,644,142,677,156,668,166,169,176,179,189,190,191,195,196,197,220,241,254,259,267,276,284,291,301,305,319,350,357,360,363,383,385,388,397,407,411,417,425,433,440,444,484,495,489 3036,832,2346,1076,191,444,1125,2488,489,397,2987,876,1222,2072,350,67,551,1281,47,190,2426,195,363,1676,360,284,1078,552,1522,2137,1387,176,417,668,2722,1153,2403,259,179,109,196,1623,1501,291,981,693,2547,3065,51,83,1333,115,3117,2678,3091,1284,833,983,962,2998,866,1081,48,35,1227,679,2932,1181,3161,383,440,407,798,558,618,305,1361,941,633,276,2378,522,554,1605,644,2320,1423,2193,2499,625,43,1453,2381,2412,411,2117,2225,241,2779,565,544,166,254,77,112,2330,425,2838,1991,724,86,89,484,357,1400,142,156,898,546,3151,388,2786,301,197,910,495,433,11,859,801,7,705,593,601,116,319,113,1147,735,220,57,6,2478,105,2151,169,577,385,135,2481,677,267,2211,189 -1.4118743308181245,0.4182557487269513,-0.5342242617338631,0.21440615544338357,1.7592151429408447,0.9765264378161742,0.1838925440088085,-0.6360363435663436,0.9207519138862322,1.0945079100252835,-1.2811099242588615,0.3759530057373177,0.12175448251162654,-0.3596472519831671,1.2064269794639189,2.329750012077,0.8167483885125356,0.09011573382996567,2.515439795372476,1.7667329517528663,-0.5948794930148794,1.751667447018552,1.176476578042439,-0.14270834812699967,1.1865067348823226,1.4228948856937176,0.21440615544338357,0.8167483885125356,-0.05719278632694883,-0.39751866108604983,0.02566161901174243,1.8112225085127378,1.0416622545332883,0.6194206088649225,-0.8509667351664257,0.1684982022009186,-0.5745186791895069,1.5017677751833673,1.803880161059405,2.1512615372917634,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,-1.492956015355766,2.5007588066882245,2.2399742438327923,0.05808732403364699,2.132957634741071,-1.778616500027411,-0.8067138905481915,-1.6042899045333228,0.09011573382996567,0.4182557487269513,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.39013449402256833,0.21440615544338357,2.515439795372476,2.596136262438205,0.12175448251162654,0.6065201023101452,-1.1555145615983378,0.15301100508827867,-2.3972018839891502,1.1358809033740525,0.9875161701203701,1.0629537868319574,0.45984406883424556,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,0.8167483885125356,-0.09107218097239303,0.6450133877649504,-0.51428752530657,0.009297339019232754,-0.43590826117893794,-0.6360363435663436,0.682890738977402,2.5443983795118403,-0.007169221259632773,-0.5543007948494578,-0.5745186791895069,1.05233382643295,-0.3785188752723304,-0.4553008972742839,1.5693674826960398,-0.9185947277776126,0.7929788244184839,0.8402742865808962,1.8760367688861144,1.5188836640650665,2.2514617717609795,2.1451816415421097,-0.51428752530657,1.0201626829533696,-0.9877693062177954,-0.303787854117314,0.5542099181825546,2.2342011612850494,2.2225958317358057,0.9320183829658302,1.1964900873490003,0.02566161901174243,1.992569263975948,1.9180197862656285,0.36168996784734275,0.8402742865808962,-2.2236327840032746,1.125611440557737,-0.9185947277776126,1.350128868152097,1.751667447018552,0.34734463722339803,0.9207519138862322,1.0093338760985888,2.984818292512709,0.4042351666901161,0.45984406883424556,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,0.1838925440088085,0.5409522516865753,1.6427531946624607,2.39928112695771,3.1003852237037637,-0.6153848387722859,2.175369810670554,-0.39751866108604983,1.854681789652418,0.7810014179820873,1.1358809033740525,2.051351117777622,-0.6153848387722859,0.6194206088649225,1.4758172511688186,-0.43590826117893794,1.7742210599427393 3193 Anion transport 48 71 5.100160301632815 3.393659397835545e-07 P12235,Q9H2D1,Q9Y277,Q9C0H2,Q9Y619,Q96S66,P07602,Q7L0J3,Q9NZJ7,P53985,P05141,Q14728,P08195,Q96NB2,Q6NUK1,Q00325,Q9UJS0,O75915,O43681,P55011,Q08722,P45880,P08183,Q9BXP2,P21796,P12236,Q9UBX3,Q15758,P53007,Q9Y6M7,Q9HC21,O43808,Q9BQT8,P30536,Q9H936,Q9H9B4,Q15907,Q8TB61,Q9NW15,O75746,P28288,Q8TDW0,P11166,Q9UHG3,Q15043,O60831,Q99808,P51798 Processes and pathways GO Biological process msigdb_gobp 259,7,135,11,267,403,20,149,148,407,284,411,417,546,419,554,169,551,557,558,306,48,176,433,51,179,57,565,440,189,319,444,197,200,593,601,216,89,220,350,473,484,612,105,241,489,372,383 3036,2346,2031,557,444,1125,489,350,551,692,284,1078,20,176,417,2722,612,259,179,2460,51,473,200,833,866,48,3161,383,440,407,1898,558,2555,554,644,306,1453,411,752,241,565,216,3026,419,1209,149,89,484,546,403,372,197,433,11,627,7,705,593,601,319,1147,220,148,57,105,169,135,2481,267,2211,189 -1.4118743308181245,-0.5342242617338631,-0.3409024311136362,0.8048943132507087,0.9765264378161742,0.1838925440088085,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.5805078633245453,1.4228948856937176,0.21440615544338357,2.762496989040066,1.8112225085127378,1.0416622545332883,-0.8509667351664257,0.7078077588474234,1.5017677751833673,1.803880161059405,-0.6153848387722859,2.5007588066882245,0.9432286304255554,1.7364816398521126,0.4182557487269513,0.39013449402256833,2.515439795372476,-2.3972018839891502,1.1358809033740525,0.9875161701203701,1.0629537868319574,-0.2671646500903092,0.8048943132507087,-0.6777844648834328,0.8167483885125356,0.6450133877649504,1.3408498426869389,-0.007169221259632773,1.05233382643295,0.5142163574940924,1.5693674826960398,0.7929788244184839,1.6586937760640963,-1.3589269339837995,1.0416622545332883,0.1374300649717309,1.952285648216789,2.2225958317358057,0.9320183829658302,0.8402742865808962,1.0735225288658525,1.1663992693165688,1.751667447018552,1.0093338760985888,2.984818292512709,0.682890738977402,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,1.293823383957412,0.1838925440088085,1.6427531946624607,1.9590621281540601,2.39928112695771,2.175369810670554,1.854681789652418,2.051351117777622,-0.6153848387722859,1.4758172511688186,-0.43590826117893794,1.7742210599427393 3193 Golgi membrane 58 135 5.088833646371748 3.60272473009552e-07 Q9UM00,P24390,Q7LGA3,Q9H7Z7,P61019,Q14108,P52292,O43505,Q9H4A6,Q96L58,Q96S66,P04439,O43731,Q9BVK6,O95197,O95295,O00461,Q9P2W9,Q99640,P61026,P49755,Q8NF37,Q86Y82,Q8IV08,Q15363,O60499,P35613,P49257,Q8N2H4,Q8NCH0,Q12893,P51572,Q16706,Q15392,Q9BUR5,L0R6Q1,O14653,Q8TB61,O60476,Q8IZA0,O95721,Q9Y3B3,Q9NTJ5,O15258,Q9Y371,O95249,Q6ZRP7,Q92896,Q10713,Q9UBF8,Q14789,Q9HC07,O15260,Q9Y282,P42345,Q9Y3E0,P10321,Q13190 Localization GO Cellular component msigdb_gocc 385,2,132,393,520,9,138,262,268,272,403,275,26,415,27,409,34,39,298,430,304,181,442,184,61,63,192,447,69,70,456,327,465,84,213,337,462,89,346,93,472,95,486,355,487,229,362,235,236,496,369,116,245,119,500,250,499,253 337,34,2486,916,462,715,355,245,782,262,2250,26,2366,346,63,1961,903,27,229,409,472,1304,275,1927,2722,499,612,669,2309,2,1156,192,2549,1033,500,1053,1602,447,2683,304,1181,327,3161,138,2638,2962,2659,1038,2660,2376,2163,1979,520,430,1055,1390,1450,758,1746,522,2115,1092,605,2116,236,456,574,253,1232,9,369,2323,2779,61,986,84,2294,465,2326,789,362,132,660,968,442,840,184,93,69,1613,1583,70,181,89,688,555,947,734,1480,1663,235,272,777,403,298,213,415,3133,1616,664,2149,268,393,932,2061,116,1147,486,753,1493,39,2101,496,2478,2953,3183,385,119,1673,2718,3128,487,95,250,1220 1.2359622824697312,2.605360668935537,-0.6360363435663436,0.3329162614491058,0.9543830980982788,0.5542099181825546,1.1964900873490003,1.5442857407745552,0.4735513630461408,1.4845046522176364,-0.4748273403029004,2.6816050945494077,-0.5543007948494578,1.216317751801572,2.346058243177083,-0.303787854117314,0.34734463722339803,2.6684245539590274,1.6104756568747511,1.05233382643295,0.9432286304255554,0.07415070895816572,1.4495286247621895,-0.28541547461577405,-0.8509667351664257,0.9094287765563077,0.7078077588474234,0.6194206088649225,-0.51428752530657,3.21572160468917,0.1684982022009186,1.7592151429408447,-0.6777844648834328,0.2445587153188426,0.9094287765563077,0.22952714396117282,-0.09107218097239303,0.9765264378161742,-0.8067138905481915,1.3408498426869389,0.15301100508827867,1.2650915011001496,-2.3972018839891502,2.0254641929604245,-0.7631090610942425,-1.2051532199617174,-0.7848314137948916,0.2445587153188426,-0.7848314137948916,-0.5543007948494578,-0.41664798954862137,-0.303787854117314,0.8866106862369233,1.0093338760985888,0.22952714396117282,0.02566161901174243,-0.007169221259632773,0.5007368375870117,-0.177690185818539,0.8866106862369233,-0.3785188752723304,0.21440615544338357,0.7201675789757652,-0.3785188752723304,1.5859138151123813,0.9654822230844401,0.7810014179820873,1.5188836640650665,0.12175448251162654,3.0232917146470886,1.1663992693165688,-0.51428752530657,-0.9185947277776126,2.3514587661376916,0.2891251966313216,2.2399742438327923,-0.494489054305589,0.9543830980982788,-0.51428752530657,0.4735513630461408,1.1865067348823226,2.070521741578072,0.6322515068949177,0.30380731745916084,0.9875161701203701,0.4182557487269513,1.7891089124911725,2.205038320950641,2.31327983578579,-0.09107218097239303,-0.07407874008591195,2.302208489423922,1.7965090219596693,2.2225958317358057,0.5935493889180543,0.8167483885125356,0.3184040786732402,0.5409522516865753,-0.023739075165896593,-0.12538587769838372,1.5941352237229818,1.4583294958454196,0.48718206135466036,1.0735225288658525,1.38683389940539,1.682361685022864,1.05233382643295,-1.9624039695245854,-0.09107218097239303,0.6322515068949177,-0.39751866108604983,1.4670922847773513,1.1152930343193794,0.3329162614491058,-0.3409024311136362,2.132957634741071,0.1838925440088085,0.9320183829658302,0.5142163574940924,-0.023739075165896593,2.572831939044648,-0.3596472519831671,0.9207519138862322,-0.6153848387722859,-1.180235642836601,-3.599840094441577,1.1358809033740525,2.1268132851345656,-0.12538587769838372,-0.8287583635800084,-1.8692775678719071,0.9320183829658302,2.1991455126433834,1.5358542924197818,0.1374300649717309 3193 Mitochondrial transmembrane transport 37 51 5.046229739472178 4.506135343639604e-07 P12235,O60830,Q9H2D1,O95831,Q9Y619,O75027,O96008,Q99595,P05141,Q9BSK2,Q96NB2,Q6P4A7,Q00325,P23786,Q9UJS0,P06576,Q8IYU8,Q9BPX6,O75964,P56385,P21796,P12236,P53007,O95202,Q9UJZ1,O43772,Q9BQT8,Q9H936,P24539,Q9H9B4,O14925,O75746,Q8WWC4,Q15388,P56134,O43615,Q3ZCQ8 Processes and pathways GO Biological process msigdb_gobp 259,5,7,389,267,397,525,19,284,162,546,166,554,167,169,552,425,301,47,305,51,179,440,190,577,191,197,593,83,601,92,350,357,232,618,376,639 92,376,191,5,397,2072,350,1281,47,1152,190,389,525,284,552,2458,259,179,51,167,83,1333,983,2932,923,440,618,305,554,232,1508,639,166,425,928,724,2021,357,546,19,301,197,162,7,593,601,1327,169,577,677,267 2.2109109040904884,1.1461017884280336,1.7592151429408447,3.1165747016179965,1.0945079100252835,-0.3596472519831671,1.2064269794639189,0.09011573382996567,2.515439795372476,0.1684982022009186,1.7667329517528663,1.1152930343193794,0.8751148153965543,1.4228948856937176,0.8167483885125356,-0.6153848387722859,1.5017677751833673,1.803880161059405,2.5007588066882245,1.8618274754931423,2.2399742438327923,0.05808732403364699,0.2891251966313216,-1.1555145615983378,0.3329162614491058,0.9875161701203701,0.6953823294342337,1.3408498426869389,0.8167483885125356,1.6023224295792171,-0.04041324981336907,0.6577068359941382,1.8760367688861144,1.0201626829533696,0.3329162614491058,0.5542099181825546,-0.32228307221127694,1.1964900873490003,0.8402742865808962,2.8113998714497686,1.350128868152097,1.751667447018552,1.8971479790749635,3.043830354362099,0.7446925671515504,0.7324623353077244,0.07415070895816572,1.854681789652418,0.7810014179820873,0.6194206088649225,1.4758172511688186 3193 er 45 86 4.96678771844354 6.807103090366768e-07 O95470,Q9UM00,O00264,Q15125,P61019,Q9UKR5,Q8NHH9,Q96GC9,O00767,Q9P2W9,Q5J8M3,Q16850,Q99640,Q96A33,P61026,Q00765,P49755,Q8NF37,P27824,O15173,Q9NQC3,Q15363,O60499,P51572,Q07065,P46977,Q86UL3,O96005,Q14739,Q8TCJ2,Q15392,Q969V3,Q9Y487,Q12981,Q969Q5,Q9NTJ5,Q9Y5M8,Q06136,Q9NPA0,O75845,P04843,O95674,Q9Y3E0,O15269,Q13190 Localization OpenCell Localization opencell_localization 128,385,258,131,520,266,271,156,416,39,550,170,298,174,430,431,304,181,311,56,59,61,63,327,73,204,334,81,210,467,84,212,88,223,226,486,108,110,239,238,490,377,250,252,253 258,416,56,252,1198,63,2424,903,238,551,1647,128,377,81,2878,888,490,815,2005,3064,2213,2849,311,1448,204,655,685,304,1203,327,2584,2899,2434,520,430,658,1057,2358,431,110,73,223,253,210,893,131,61,84,788,682,170,550,1209,3016,334,909,989,181,271,689,467,2333,734,226,212,174,1064,156,298,1026,2770,826,860,239,59,594,486,1170,1493,39,266,385,3008,250,88,108 1.5017677751833673,1.0416622545332883,2.39928112695771,1.5188836640650665,0.1374300649717309,2.346058243177083,-0.5948794930148794,0.34734463722339803,1.5776579775269348,0.8167483885125356,-0.12538587769838372,2.0894866813375814,1.1461017884280336,2.2399742438327923,-1.0585470825916556,0.36168996784734275,0.9207519138862322,0.4321969562595515,-0.32228307221127694,-1.492956015355766,-0.4553008972742839,-1.011180888611287,1.3221664240422288,-0.007169221259632773,1.7211740059471201,0.6322515068949177,0.5935493889180543,1.3408498426869389,0.1374300649717309,1.2650915011001496,-0.6988844633124501,-1.082506135737104,-0.5948794930148794,0.8866106862369233,1.0093338760985888,0.6322515068949177,0.22952714396117282,-0.5342242617338631,1.0093338760985888,2.1512615372917634,2.28546270022205,1.6266810625618235,1.5188836640650665,1.6979807301199143,0.36168996784734275,2.070521741578072,2.3514587661376916,2.2399742438327923,0.4735513630461408,0.6065201023101452,1.8475085220023033,0.8285415486462114,0.1374300649717309,-1.3327768033414031,1.2457167051043052,0.34734463722339803,0.2891251966313216,1.7965090219596693,1.4583294958454196,0.5935493889180543,0.9543830980982788,-0.51428752530657,0.5409522516865753,1.6185951277994044,1.682361685022864,1.825821535867474,0.22952714396117282,1.9180197862656285,1.38683389940539,0.25950170179577764,-0.8958829370602809,0.4321969562595515,0.4042351666901161,1.5776579775269348,2.3887739794503915,0.7446925671515504,0.9320183829658302,0.1684982022009186,-0.023739075165896593,2.572831939044648,1.4758172511688186,1.1358809033740525,-1.3068387009445777,1.5358542924197818,2.2284083926639537,2.163357703140536 3193 Lysosome 31 49 4.962238075956582 6.968550458369024e-07 P50897,Q14108,O75503,P10253,P38571,P53634,P07602,Q9NZJ7,O14773,Q9UBR2,O43681,Q13510,P04062,Q9UMR5,Q8NCC3,Q15904,P13473,P07686,Q93050,P17900,P11279,P16278,P11117,Q9Y487,P10619,P15586,P06865,Q99538,P61916,P06280,P54802 Processes and pathways KEGG Pathways msigdb_kegg 8,9,139,145,526,402,20,148,150,293,557,45,53,188,193,323,72,584,208,79,206,82,85,88,98,225,224,365,491,244,126 1013,765,916,150,2033,557,2366,139,53,591,244,224,20,584,1677,145,98,85,206,669,72,1258,225,82,79,1155,526,8,402,126,1038,1361,491,2589,2116,45,9,323,193,208,365,1616,148,293,2151,1672,188,714,88 0.25950170179577764,0.48718206135466036,0.3329162614491058,1.945483805688231,-0.3409024311136362,0.8048943132507087,-0.5543007948494578,2.0123785518790727,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,2.762496989040066,0.7568588077238091,-0.14270834812699967,1.9658133945446885,2.1872987787678158,2.2342011612850494,1.7057429944746445,0.6194206088649225,2.291063262623579,0.1059833465335269,1.6185951277994044,2.2399742438327923,2.2457277457630314,0.1684982022009186,0.8751148153965543,3.0232917146470886,1.0735225288658525,2.095763221365341,0.2445587153188426,0.04192461851956566,0.9207519138862322,-0.6988844633124501,-0.3785188752723304,2.5348046058833917,3.0232917146470886,1.284289708677259,1.7592151429408447,1.7057429944746445,1.176476578042439,-0.09107218097239303,1.9590621281540601,1.3959088234962316,-0.39751866108604983,-0.12538587769838372,1.7816796524116962,0.5673949130081869,2.2284083926639537 3193 Inorganic molecular entity transmembrane transporter activity 48 74 4.946715632600224 7.547611076343048e-07 Q9UM00,P12235,Q9UDW1,Q9Y277,Q02978,P98194,Q9C0H2,Q96ES6,Q96S66,P05141,P08195,P08574,P20020,Q00325,P47985,P06576,Q13423,O43681,P55011,O75964,P45880,Q9BXP2,P56385,P21796,Q9H2J7,Q9UBX3,Q9Y6M7,O95202,P21281,P00403,P16615,Q93050,Q9H936,P24539,Q8TAD4,Q9Y487,Q9NW15,Q8TDW0,Q99797,P56134,P13073,P05023,Q7KZN9,Q9HD20,Q15043,Q9HC07,Q6P4Q7,P51798 Functions GO Molecular function msigdb_gomf 385,259,6,135,644,522,11,142,403,284,417,668,291,554,679,552,43,557,558,47,48,433,305,51,705,57,189,190,693,195,196,208,593,83,86,88,220,484,359,618,109,363,112,113,241,116,254,383 3036,557,1281,47,190,195,363,1676,284,552,1522,1387,417,668,2722,1153,259,109,196,291,981,693,2547,51,83,1333,1284,833,983,962,2998,48,679,2932,3161,383,558,618,305,1361,941,522,554,1605,644,43,241,3026,254,112,724,86,484,1400,208,142,403,359,433,11,859,705,593,116,113,220,57,6,2151,385,135,88,2211,189 -1.4118743308181245,0.8048943132507087,0.09011573382996567,2.515439795372476,1.7667329517528663,1.751667447018552,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.8167483885125356,-0.05719278632694883,0.02566161901174243,1.0416622545332883,0.6194206088649225,-0.8509667351664257,0.1684982022009186,1.5017677751833673,2.1512615372917634,1.751667447018552,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,2.5007588066882245,2.2399742438327923,0.05808732403364699,0.09011573382996567,0.4182557487269513,0.2891251966313216,0.30380731745916084,-1.3068387009445777,2.515439795372476,0.6065201023101452,-1.1555145615983378,-2.3972018839891502,1.1358809033740525,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.8866106862369233,0.8167483885125356,-0.09107218097239303,0.6450133877649504,2.5443983795118403,1.5693674826960398,-1.3589269339837995,1.5188836640650665,2.1451816415421097,0.5542099181825546,2.2342011612850494,0.9320183829658302,0.02566161901174243,1.7057429944746445,1.992569263975948,1.0735225288658525,1.1964900873490003,1.0093338760985888,2.984818292512709,0.4042351666901161,0.5805078633245453,0.7446925671515504,2.132957634741071,2.1451816415421097,1.6427531946624607,2.39928112695771,3.1003852237037637,-0.39751866108604983,1.1358809033740525,2.051351117777622,2.2284083926639537,-0.43590826117893794,1.7742210599427393 3193 Intrinsic component of endoplasmic reticulum membrane 30 48 4.878435775059367 1.0693047052198818e-06 O95470,Q9UM00,Q15125,Q9UBM7,Q9BUN8,P04439,Q03518,O00767,Q5J8M3,Q86YN1,Q96A33,Q99442,P27824,Q9Y4P3,Q9NQC3,O75844,P51572,Q9P035,Q8TCT9,Q92643,Q86XL3,Q9Y282,Q8TB61,Q12981,Q9H490,Q9NPA0,Q15629,O76024,P10321,P57088 Localization GO Cellular component msigdb_gocc 128,385,131,400,147,275,152,416,550,171,174,432,311,183,59,67,327,203,80,468,335,119,89,223,366,239,114,247,499,255 666,416,67,247,128,1304,275,499,2185,311,2037,327,255,941,152,223,2018,893,131,114,2326,550,733,335,171,909,89,80,468,1401,174,663,432,1026,147,366,726,239,59,556,203,1170,1353,400,385,119,183,1439 0.6194206088649225,1.0416622545332883,2.329750012077,1.5358542924197818,2.0894866813375814,0.07415070895816572,1.4495286247621895,0.9094287765563077,-0.43590826117893794,1.3221664240422288,-0.3409024311136362,1.2650915011001496,1.510343999684222,0.3184040786732402,1.9386564503168657,1.6266810625618235,-0.32228307221127694,0.36168996784734275,2.070521741578072,2.1390803803002107,-0.51428752530657,0.8285415486462114,0.5409522516865753,1.2457167051043052,1.8330785657592543,0.34734463722339803,2.2225958317358057,2.2457277457630314,0.9543830980982788,0.02566161901174243,1.825821535867474,0.6322515068949177,1.0093338760985888,0.25950170179577764,1.9658133945446885,1.176476578042439,0.5542099181825546,1.5776579775269348,2.3887739794503915,0.8167483885125356,1.7288431475403072,0.1684982022009186,0.05808732403364699,1.0840404415884148,1.1358809033740525,2.1268132851345656,1.7965090219596693,0.009297339019232754 3193 Mitochondrial transport 46 86 4.872600489093237 1.1013880248274598e-06 Q5JRX3,Q9P0J0,P12235,Q53H12,O60830,O95831,Q9NS69,P55786,Q8N4H5,O96008,Q99595,Q96EK5,P05141,Q16611,Q9Y512,Q6NUK1,O14737,P23786,Q9UJS0,P06576,Q9GZY8,O75964,P45880,O00165,P56385,P52789,Q9UBX3,Q14849,Q9UJZ1,O43772,Q15070,P49257,P51572,P30536,O75431,P24539,Q9Y5L4,O14925,Q9Y5J9,Q9Y371,Q8WWC4,Q99797,Q15388,P56134,Q10713,O43615 Processes and pathways GO Biological process msigdb_gobp 512,129,259,387,5,389,10,396,15,525,19,414,284,544,290,419,294,167,169,552,299,47,48,303,305,435,57,58,577,191,65,447,327,200,583,83,602,92,488,487,357,359,232,618,236,376 303,1279,294,92,716,376,191,5,583,2072,1281,47,1152,769,2636,718,2829,389,525,1356,284,552,1413,1622,2458,259,2287,167,83,1333,2678,2373,200,2832,983,2706,48,2932,2187,447,2467,923,327,435,396,618,305,2963,236,58,65,232,2168,544,639,387,512,419,968,969,1137,15,928,357,881,414,949,1909,19,359,299,1327,2448,10,129,1884,3005,57,730,169,577,862,487,290,488,602 1.3408498426869389,0.09011573382996567,1.38683389940539,2.2109109040904884,0.5542099181825546,1.1461017884280336,1.7592151429408447,3.1165747016179965,0.7568588077238091,-0.3596472519831671,0.09011573382996567,2.515439795372476,0.1684982022009186,0.48718206135466036,-0.7631090610942425,0.5542099181825546,-0.9877693062177954,1.1152930343193794,0.8751148153965543,0.04192461851956566,1.4228948856937176,0.8167483885125356,0.009297339019232754,-0.1081741936250891,-0.6153848387722859,1.5017677751833673,-0.494489054305589,1.8618274754931423,2.2399742438327923,0.05808732403364699,-0.8067138905481915,-0.5543007948494578,1.7364816398521126,-0.9877693062177954,0.2891251966313216,-0.8287583635800084,2.515439795372476,-1.1555145615983378,-0.43590826117893794,0.9765264378161742,-0.6153848387722859,0.3329162614491058,1.2650915011001496,0.9984518432806867,1.1049253152266847,0.6953823294342337,1.3408498426869389,-1.2051532199617174,1.5859138151123813,2.394036011434074,2.3406400045953175,1.6023224295792171,-0.41664798954862137,0.8402742865808962,0.6577068359941382,1.125611440557737,0.8980485194817284,1.0416622545332883,0.30380731745916084,0.30380731745916084,0.1838925440088085,2.9120109684113684,0.3329162614491058,1.1964900873490003,0.3759530057373177,1.05233382643295,0.3184040786732402,-0.2671646500903092,2.8113998714497686,1.1964900873490003,1.38683389940539,0.07415070895816572,-0.5948794930148794,3.0024397548003465,2.0831876730587275,-0.24903411518852805,-1.3068387009445777,2.39928112695771,0.5542099181825546,1.854681789652418,0.7810014179820873,0.4042351666901161,0.9320183829658302,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 SLC superfamily of solute carriers 38 44 4.862489460069744 1.1591855315927852e-06 P12235,Q9H2D1,Q9Y619,Q9Y6C9,Q9NZJ7,Q7L0J3,P53985,Q9H2V7,P05141,P08195,Q9BSK2,Q6NUK1,Q96NB2,Q00325,Q9UJS0,P55011,Q9BXP2,P12236,Q15758,P53007,Q9UBX3,Q9Y6M7,O95202,O43772,Q9HC21,O43808,Q9BQT8,Q70HW3,Q9H936,Q8TAD4,Q9H9B4,Q8TB61,O75746,P11166,Q15043,Q9HC07,Q99808,Q8IXU6 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 259,7,267,143,148,149,407,155,284,417,162,419,546,554,169,558,433,179,565,440,57,189,190,191,319,444,197,77,593,86,601,89,350,612,241,116,372,246 191,444,350,190,284,417,612,259,179,866,440,407,558,554,644,241,565,3026,419,1209,77,149,246,86,89,546,372,197,162,433,859,7,705,155,593,601,116,319,148,57,169,267,143,189 1.7592151429408447,0.9765264378161742,1.2064269794639189,1.7667329517528663,1.4228948856937176,1.0416622545332883,0.7078077588474234,1.5017677751833673,1.803880161059405,0.39013449402256833,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.8167483885125356,0.6450133877649504,1.5693674826960398,0.7929788244184839,-1.3589269339837995,1.0416622545332883,0.1374300649717309,2.2514617717609795,1.952285648216789,1.5442857407745552,2.2342011612850494,2.2225958317358057,0.8402742865808962,1.1663992693165688,1.751667447018552,1.8971479790749635,1.0093338760985888,0.4042351666901161,3.043830354362099,0.5805078633245453,1.9249245939305628,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,1.9590621281540601,2.39928112695771,1.854681789652418,1.4758172511688186,1.992569263975948,1.7742210599427393 3193 Inner mitochondrial membrane protein complex 41 70 4.82437252840385 1.4044470399987574e-06 Q9P0J0,Q53H12,Q5XKP0,O60830,Q9UDW1,Q99623,Q9NX14,O43676,P14406,Q99595,P51970,O95168,Q9NVH1,P09669,Q9Y4W6,O75306,Q9Y512,P08574,Q13505,O14949,P06576,P21912,Q8IYU8,Q9BPX6,O75964,P56385,P12236,Q96CU9,Q16891,P00403,Q9NX63,O75431,P24539,Q9BUR5,O14925,Q6UXV4,P22695,P56134,P13073,Q96IX5,Q3ZCQ8 Localization GO Cellular component msigdb_gocc 129,387,260,5,6,388,530,16,18,19,656,404,408,652,677,543,290,668,36,37,552,553,425,301,47,305,179,60,318,195,461,583,83,213,92,352,97,618,109,637,639 2540,832,92,37,16,5,876,543,958,583,1557,1281,47,404,1963,847,195,552,668,652,1153,179,109,18,770,922,3040,981,553,97,83,1333,2959,1795,1284,786,983,2465,679,2932,3049,656,618,305,36,1507,1002,318,639,387,260,352,425,724,60,637,19,388,301,213,1327,408,530,461,129,6,862,677,290,935 -0.6777844648834328,0.4182557487269513,2.2109109040904884,2.58685650649295,2.850934877568107,3.1165747016179965,0.3759530057373177,0.8402742865808962,0.30380731745916084,0.7568588077238091,-0.07407874008591195,0.09011573382996567,2.515439795372476,1.0629537868319574,-0.303787854117314,0.4042351666901161,1.751667447018552,0.8167483885125356,0.6194206088649225,0.6322515068949177,0.1684982022009186,1.803880161059405,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,-1.4118743308181245,0.2891251966313216,0.8167483885125356,2.1932323689347277,2.2399742438327923,0.05808732403364699,-1.2051532199617174,-0.213128942203161,0.09011573382996567,0.4735513630461408,0.2891251966313216,-0.6153848387722859,0.6065201023101452,-1.1555145615983378,-1.4386772460322241,0.6322515068949177,0.6953823294342337,1.3408498426869389,2.596136262438205,-0.04041324981336907,0.27435692511880505,1.293823383957412,0.6577068359941382,1.125611440557737,1.5017677751833673,1.2064269794639189,1.0201626829533696,0.5542099181825546,2.356841664788679,0.6703324293561015,2.8113998714497686,1.125611440557737,1.350128868152097,1.682361685022864,0.07415070895816572,1.0629537868319574,0.8751148153965543,0.9654822230844401,2.0831876730587275,3.1003852237037637,0.4042351666901161,0.6194206088649225,1.4049437781239236,0.3329162614491058 3193 Endoplasmic reticulum 79 193 4.756768571809543 1.967164687588508e-06 P43307,Q13724,P51571,O43169,O43731,O95197,Q8N0U8,Q13217,Q9P2W9,Q9Y680,Q9NZ01,O75915,Q96CS3,Q14849,Q9NQC3,P51648,Q8TCT9,O96005,P37268,Q86UE4,Q15800,Q9BV10,Q96G23,Q96A57,Q96KA5,Q96KC8,O95470,Q70UQ0,Q15125,Q9H3G5,Q5BJF2,Q9BUN8,Q03518,Q96GC9,P84157,Q16850,Q96A33,Q96PC5,Q8NF37,Q8IV08,Q14257,Q9P035,Q12981,O75845,Q15043,P35790,Q6NUQ4,O15260,O15269,O00264,P50402,Q8NHH9,P21964,P27824,Q99735,O43852,Q96HY6,Q9H3N1,P51572,Q86XL3,Q9BT22,Q96CN7,Q8NHP6,Q6UW68,O95674,Q9UM00,Q9UBM7,Q96S66,P35610,O00767,Q00765,Q99442,Q6UWP7,P49257,Q96AG4,Q8TCJ2,P13674,P04843,O60831 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 0,511,519,25,26,27,30,549,39,40,556,551,560,58,59,71,80,81,99,102,107,111,118,121,124,125,128,130,131,133,144,147,152,156,165,170,174,180,181,184,186,203,223,238,241,242,243,245,252,258,261,271,288,311,314,315,326,329,327,335,342,341,340,370,377,385,400,403,410,416,431,432,441,447,458,467,464,490,489 258,416,1104,715,245,252,1123,25,2542,26,315,582,489,980,238,551,651,1015,27,1647,128,377,81,888,490,815,3087,1078,684,2369,2457,2722,1651,1597,464,1256,1443,2371,960,2285,2286,1794,3081,288,2620,1969,2184,1562,2185,311,2979,2037,3067,1156,410,242,1563,99,1448,2431,0,1158,2745,1359,1418,1863,1083,685,1307,447,261,1159,2583,519,327,71,2899,2219,2851,1742,708,941,658,2258,1712,2777,1900,757,1263,2406,2869,2040,1867,758,2586,2114,2552,2708,2553,2141,985,1744,3153,1110,1803,906,165,431,152,2013,1452,223,1393,549,1093,511,186,2018,1207,1429,58,2225,241,1937,131,759,2855,788,107,2326,170,3167,144,243,1716,370,441,130,102,733,335,184,640,30,1269,2148,181,271,340,467,80,1433,990,1211,174,121,458,341,560,648,118,156,326,124,125,180,403,432,314,2510,1026,342,147,111,664,133,329,726,59,594,2246,556,203,1493,1353,39,400,2392,2279,571,385,1758,40 1.5017677751833673,1.0416622545332883,0.19919490676105286,0.5542099181825546,1.5442857407745552,1.5188836640650665,0.1838925440088085,2.6859731952221364,-0.6777844648834328,2.6816050945494077,1.3033138565109923,0.7568588077238091,0.9207519138862322,0.2891251966313216,1.5776579775269348,0.8167483885125356,0.6322515068949177,0.25950170179577764,2.6684245539590274,-0.12538587769838372,2.0894866813375814,1.1461017884280336,2.2399742438327923,0.36168996784734275,0.9207519138862322,0.4321969562595515,-1.5761016275345998,0.21440615544338357,0.5935493889180543,-0.5543007948494578,-0.6153848387722859,-0.8509667351664257,-0.12538587769838372,-0.09107218097239303,0.9543830980982788,0.1059833465335269,-0.007169221259632773,-0.5543007948494578,0.30380731745916084,-0.494489054305589,-0.494489054305589,-0.213128942203161,-1.5481519943674076,1.4049437781239236,-0.7415449896710221,-0.303787854117314,-0.43590826117893794,-0.07407874008591195,-0.43590826117893794,1.3221664240422288,-1.2555878176142559,-0.3409024311136362,-1.492956015355766,0.1684982022009186,1.05233382643295,1.5610421002753638,-0.07407874008591195,2.1872987787678158,-0.007169221259632773,-0.5948794930148794,3.2740327620941194,0.1684982022009186,-0.8733409382481655,0.04192461851956566,0.009297339019232754,-0.24903411518852805,0.21440615544338357,0.5935493889180543,0.07415070895816572,0.9765264378161742,1.4931547427369818,0.1684982022009186,-0.6988844633124501,0.8866106862369233,1.2650915011001496,2.2966451596705606,-1.082506135737104,-0.4553008972742839,-1.011180888611287,-0.177690185818539,0.5673949130081869,0.3184040786732402,0.6322515068949177,-0.4748273403029004,-0.16014273539632354,-0.9185947277776126,-0.2671646500903092,0.5007368375870117,0.1059833465335269,-0.5745186791895069,-1.0347727466327314,-0.3409024311136362,-0.24903411518852805,0.5007368375870117,-0.6988844633124501,-0.3785188752723304,-0.6777844648834328,-0.8287583635800084,-0.6777844648834328,-0.39751866108604983,0.2891251966313216,-0.177690185818539,-2.2576840703065586,0.19919490676105286,-0.213128942203161,0.34734463722339803,1.8760367688861144,1.0093338760985888,1.9386564503168657,-0.32228307221127694,-0.007169221259632773,1.6266810625618235,0.02566161901174243,0.8285415486462114,0.21440615544338357,0.8980485194817284,1.7816796524116962,-0.32228307221127694,0.1374300649717309,0.009297339019232754,2.394036011434074,-0.4553008972742839,1.5693674826960398,-0.28541547461577405,2.070521741578072,0.5007368375870117,-1.011180888611287,0.4735513630461408,2.163357703140536,-0.51428752530657,1.8475085220023033,-2.579445170109499,1.9859173850366558,1.5610421002753638,-0.16014273539632354,1.1663992693165688,0.9875161701203701,2.0768660692333203,2.181344630255124,0.5409522516865753,1.2457167051043052,1.7891089124911725,0.6577068359941382,2.650670416030812,0.1059833465335269,-0.39751866108604983,1.7965090219596693,1.4583294958454196,1.2359622824697312,0.9543830980982788,2.2457277457630314,0.009297339019232754,0.2891251966313216,0.1374300649717309,1.825821535867474,2.1206472108366774,0.9654822230844401,1.2359622824697312,0.8048943132507087,0.6450133877649504,2.1268132851345656,1.9180197862656285,1.2747125192304771,2.1082494009679316,2.1020174194592656,1.803880161059405,1.0735225288658525,1.0093338760985888,1.3127614347392678,-0.6360363435663436,0.25950170179577764,1.2359622824697312,1.9658133945446885,2.1512615372917634,0.6322515068949177,2.0641545608121326,1.2650915011001496,0.5542099181825546,2.3887739794503915,0.7446925671515504,-0.4553008972742839,0.8167483885125356,1.7288431475403072,-0.023739075165896593,0.05808732403364699,2.572831939044648,1.0840404415884148,-0.5543007948494578,-0.4748273403029004,0.7929788244184839,1.1358809033740525,-0.177690185818539,2.572831939044648 3193 Intrinsic component of mitochondrial membrane 32 47 4.750885449307177 2.025278442951972e-06 P12235,Q9Y2R0,O60830,Q5XKP0,Q53H12,O75880,O96008,Q99595,Q9NVH1,Q16611,Q9Y512,Q96NB2,Q13505,Q6P4A7,Q00325,Q9GZY8,Q9BPX6,O43819,Q16891,Q9HC21,Q15070,Q9NX63,O75431,P17152,Q9BUR5,Q8IWA4,Q9BWH2,O14925,P57105,Q6UXV4,Q15388,Q9H3K2 Localization GO Cellular component msigdb_gocc 259,4,5,260,387,395,525,19,408,544,290,546,36,166,554,299,301,175,318,319,65,461,583,592,213,218,479,92,222,352,232,234 92,175,5,583,395,1152,769,525,259,592,2465,2374,923,222,554,36,65,232,821,544,318,387,260,166,352,218,969,1137,724,881,546,19,301,213,479,299,234,601,1512,319,2448,408,461,1406,4,677,290 2.2109109040904884,1.8185362415383943,3.1165747016179965,0.7568588077238091,1.1049253152266847,0.1684982022009186,0.48718206135466036,0.8751148153965543,1.5017677751833673,0.7446925671515504,-0.6153848387722859,-0.5543007948494578,0.3329162614491058,1.6266810625618235,0.8167483885125356,2.596136262438205,2.3406400045953175,1.6023224295792171,0.4321969562595515,0.8402742865808962,1.293823383957412,1.125611440557737,1.5017677751833673,1.8760367688861144,1.2064269794639189,1.6586937760640963,0.30380731745916084,0.1838925440088085,0.5542099181825546,0.3759530057373177,0.8402742865808962,2.8113998714497686,1.350128868152097,1.682361685022864,0.9432286304255554,1.38683389940539,1.6023224295792171,0.7324623353077244,-0.04041324981336907,1.293823383957412,-0.5948794930148794,1.0629537868319574,0.9654822230844401,0.02566161901174243,3.129385678191442,0.6194206088649225,1.4049437781239236 3193 Ion transport 101 200 4.739398763645619 2.1435329666807945e-06 Q9UDW1,Q9H2D1,P98194,Q9C0H2,O96008,P07602,Q16611,Q96NB2,P46934,Q00325,P06576,Q13423,O75915,O43681,P55011,O75964,P45880,P21796,O15173,Q9UBX3,Q15758,Q9UJZ1,O75844,Q70HW3,Q9H936,P24539,Q9H9B4,Q8TAD4,Q8TB61,P11166,P56134,Q9UHG3,P13073,Q9H0H5,Q7KZN9,Q9HD20,Q9HC07,P27105,Q12959,P62258,Q9Y277,Q02978,Q96ES6,Q9NZJ7,Q7L0J3,Q9Y4W6,Q96GC9,P08574,Q6P4A7,P47985,Q9UJS0,P08183,P12236,Q9H2J7,Q9Y6M7,O95202,P46459,P21281,O43772,P00403,P16615,Q9BQT8,P30536,P02786,Q15907,Q9NW15,Q15043,O76024,Q6P4Q7,P12235,Q9Y619,P62942,Q8NE01,P05141,P20020,Q9BPX6,Q08722,P56385,Q9HC21,O75746,Q8WWC4,P05067,P05023,Q99808,P51798,Q9UM00,Q99623,O75027,Q96S66,P53985,Q14728,P08195,Q6NUK1,Q8IYU8,Q9BXP2,P53007,O43808,P28288,Q8TDW0,Q9BVC6,O60831 Processes and pathways GO Biological process msigdb_gobp 6,7,522,11,525,20,544,546,35,554,552,43,551,557,558,47,48,51,56,57,565,577,67,77,593,83,601,86,89,612,618,105,109,627,112,113,116,115,625,633,135,644,142,148,149,677,156,668,166,679,169,176,179,705,189,190,694,693,191,195,196,197,200,209,216,220,241,247,254,259,267,276,280,284,291,301,306,305,319,350,357,360,363,372,383,385,388,397,403,407,411,417,419,425,433,440,444,473,484,495,489 2301,3036,1249,832,2346,2031,999,56,557,1076,191,444,1125,2488,489,397,2987,876,1222,2072,350,67,551,1281,47,247,190,2426,525,195,209,692,1730,363,1676,360,284,1078,1596,552,1522,2137,20,1387,176,417,668,2722,1153,612,1792,2403,259,179,109,2352,2460,196,1623,1501,291,981,693,2547,3065,51,83,1358,1333,115,3117,473,2678,200,3091,1284,865,833,1128,983,962,2998,866,1081,48,694,35,1227,679,2932,1181,3161,383,1085,440,407,1898,798,558,618,305,1089,1361,941,633,276,2378,2555,522,554,1605,2589,1132,644,2320,1423,2836,306,2193,2499,625,43,1453,1425,2381,2412,411,2117,2225,752,241,2779,565,216,544,1002,3026,419,1209,166,254,77,112,149,2330,425,2838,1991,280,724,86,89,484,357,1400,142,156,898,546,403,3151,388,372,2786,301,197,910,495,433,11,627,859,801,7,705,593,601,116,319,113,1147,735,220,148,57,6,2478,105,2151,169,577,385,2903,978,135,2481,677,267,2211,189 -0.51428752530657,-1.4118743308181245,0.1059833465335269,0.4182557487269513,-0.5342242617338631,-0.3409024311136362,0.27435692511880505,2.39928112695771,0.8048943132507087,0.21440615544338357,1.7592151429408447,0.9765264378161742,0.1838925440088085,-0.6360363435663436,0.9207519138862322,1.0945079100252835,-1.2811099242588615,0.3759530057373177,0.12175448251162654,-0.3596472519831671,1.2064269794639189,2.329750012077,0.8167483885125356,0.09011573382996567,2.515439795372476,1.5358542924197818,1.7667329517528663,-0.5948794930148794,0.8751148153965543,1.751667447018552,1.6979807301199143,0.5805078633245453,-0.177690185818539,1.176476578042439,-0.14270834812699967,1.1865067348823226,1.4228948856937176,0.21440615544338357,-0.09107218097239303,0.8167483885125356,-0.05719278632694883,-0.39751866108604983,2.762496989040066,0.02566161901174243,1.8112225085127378,1.0416622545332883,0.6194206088649225,-0.8509667351664257,0.1684982022009186,0.7078077588474234,-0.213128942203161,-0.5745186791895069,1.5017677751833673,1.803880161059405,2.1512615372917634,-0.5342242617338631,-0.6153848387722859,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,-1.492956015355766,2.5007588066882245,2.2399742438327923,0.04192461851956566,0.05808732403364699,2.132957634741071,-1.778616500027411,0.9432286304255554,-0.8067138905481915,1.7364816398521126,-1.6042899045333228,0.09011573382996567,0.39013449402256833,0.4182557487269513,0.1838925440088085,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.39013449402256833,0.21440615544338357,2.515439795372476,0.5805078633245453,2.596136262438205,0.12175448251162654,0.6065201023101452,-1.1555145615983378,0.15301100508827867,-2.3972018839891502,1.1358809033740525,0.21440615544338357,0.9875161701203701,1.0629537868319574,-0.2671646500903092,0.45984406883424556,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.21440615544338357,0.04192461851956566,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,-0.6777844648834328,0.8866106862369233,0.8167483885125356,-0.09107218097239303,-0.6988844633124501,0.1838925440088085,0.6450133877649504,-0.51428752530657,0.009297339019232754,-0.9877693062177954,1.3408498426869389,-0.43590826117893794,-0.6360363435663436,0.682890738977402,2.5443983795118403,-0.007169221259632773,0.009297339019232754,-0.5543007948494578,-0.5745186791895069,1.05233382643295,-0.3785188752723304,-0.4553008972742839,0.5142163574940924,1.5693674826960398,-0.9185947277776126,0.7929788244184839,1.6586937760640963,0.8402742865808962,0.27435692511880505,-1.3589269339837995,1.0416622545332883,0.1374300649717309,1.8760367688861144,1.5188836640650665,2.2514617717609795,2.1451816415421097,1.952285648216789,-0.51428752530657,1.0201626829533696,-0.9877693062177954,-0.303787854117314,1.4406894094750298,0.5542099181825546,2.2342011612850494,2.2225958317358057,0.9320183829658302,1.1964900873490003,0.02566161901174243,1.992569263975948,1.9180197862656285,0.36168996784734275,0.8402742865808962,1.0735225288658525,-2.2236327840032746,1.125611440557737,1.1663992693165688,-0.9185947277776126,1.350128868152097,1.751667447018552,0.34734463722339803,0.9207519138862322,1.0093338760985888,2.984818292512709,0.682890738977402,0.4042351666901161,0.45984406883424556,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,0.1838925440088085,0.5409522516865753,1.6427531946624607,1.9590621281540601,2.39928112695771,3.1003852237037637,-0.6153848387722859,2.175369810670554,-0.39751866108604983,1.854681789652418,0.7810014179820873,1.1358809033740525,-1.082506135737104,0.30380731745916084,2.051351117777622,-0.6153848387722859,0.6194206088649225,1.4758172511688186,-0.43590826117893794,1.7742210599427393 3193 Secretory granule membrane 28 62 4.713583508028195 2.433979080285198e-06 O00264,P42785,P10253,P07602,Q9NZJ7,P30519,P61026,Q08722,P49755,Q5T9A4,Q8NF37,Q15363,P35613,O75592,P13473,Q07065,Q93050,P11279,O15126,Q8NHP6,Q92542,Q8TAD4,O95721,Q969Q5,P27105,O15260,P10321,Q9NQX7 Localization GO Cellular component msigdb_gocc 258,136,145,20,148,32,430,306,304,309,181,61,192,445,72,73,208,206,463,340,211,86,472,226,115,245,499,127 2301,258,463,245,2488,623,2002,2348,445,2702,472,1304,20,145,499,206,669,72,2284,1445,115,32,3091,1525,192,1448,136,1566,304,1530,890,1085,2962,1130,430,1055,2408,2358,73,306,1342,1749,880,671,61,772,309,523,181,340,86,211,208,226,883,1616,859,860,127,148,1493,1553 -0.51428752530657,1.5017677751833673,0.9543830980982788,1.5442857407745552,-0.6360363435663436,0.682890738977402,-0.32228307221127694,-0.5342242617338631,0.9765264378161742,-0.8287583635800084,0.9432286304255554,0.07415070895816572,2.762496989040066,1.9658133945446885,0.9094287765563077,1.7057429944746445,0.6194206088649225,2.291063262623579,-0.494489054305589,-0.007169221259632773,2.132957634741071,2.637217657100284,-1.6042899045333228,-0.05719278632694883,1.7592151429408447,-0.007169221259632773,2.0384546855538916,-0.07407874008591195,1.3408498426869389,-0.05719278632694883,0.36168996784734275,0.21440615544338357,-1.2051532199617174,0.1838925440088085,1.0093338760985888,0.22952714396117282,-0.5745186791895069,-0.5342242617338631,2.28546270022205,1.3408498426869389,0.05808732403364699,-0.177690185818539,0.3759530057373177,0.6194206088649225,2.3514587661376916,0.48718206135466036,1.3315291268555391,0.8866106862369233,1.7965090219596693,1.2359622824697312,2.2342011612850494,1.682361685022864,1.7057429944746445,1.6185951277994044,0.3759530057373177,-0.09107218097239303,0.4042351666901161,0.4042351666901161,2.095763221365341,1.9590621281540601,-0.023739075165896593,-0.05719278632694883 3193 Cation transmembrane transport 58 118 4.704475255401247 2.5451973233447944e-06 Q9UM00,P12235,Q99623,Q9UDW1,P98194,Q9Y619,O75027,Q96ES6,P62942,Q9Y4W6,Q96GC9,P05141,P08195,Q96NB2,P46934,P08574,P20020,Q00325,P47985,P06576,Q13423,Q8IYU8,P55011,O75964,Q9BPX6,Q9BXP2,P56385,P21796,Q9H2J7,Q15758,Q9Y6M7,Q9UJZ1,O95202,O43772,P21281,Q9HC21,P00403,P16615,Q70HW3,Q9H936,Q8NE86,P24539,Q9H9B4,Q8TAD4,Q9NW15,Q8WWC4,P05067,P56134,P13073,P05023,Q7KZN9,Q9HD20,Q15043,Q9HC07,P27105,Q12959,P62258,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 385,259,388,6,522,267,397,142,276,677,156,284,417,546,35,668,291,554,679,552,43,425,558,47,301,433,305,51,705,565,189,577,190,191,693,319,195,196,77,593,724,83,601,86,220,357,360,618,109,363,112,113,241,116,115,625,633,254 832,2346,1076,191,2488,397,876,1222,2072,1281,47,190,2426,195,363,1676,360,284,1078,552,1522,2137,1387,417,668,1153,2403,259,109,196,1623,1501,291,981,693,2547,3065,51,83,1333,115,3117,2678,3091,1284,983,962,2998,1081,35,1227,679,2932,1181,3161,798,558,618,305,1361,941,633,276,2378,522,554,1605,2320,1423,2193,2499,625,43,2381,2412,2225,241,2779,565,254,77,112,2330,425,2838,1991,724,86,357,1400,142,156,898,546,3151,388,2786,301,910,433,859,801,705,593,601,116,319,113,735,220,6,2478,2151,577,385,677,267,189 0.4182557487269513,-0.5342242617338631,0.21440615544338357,1.7592151429408447,-0.6360363435663436,1.0945079100252835,0.3759530057373177,0.12175448251162654,-0.3596472519831671,0.09011573382996567,2.515439795372476,1.7667329517528663,-0.5948794930148794,1.751667447018552,1.176476578042439,-0.14270834812699967,1.1865067348823226,1.4228948856937176,0.21440615544338357,0.8167483885125356,-0.05719278632694883,-0.39751866108604983,0.02566161901174243,1.0416622545332883,0.6194206088649225,0.1684982022009186,-0.5745186791895069,1.5017677751833673,2.1512615372917634,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,-1.492956015355766,2.5007588066882245,2.2399742438327923,0.05808732403364699,2.132957634741071,-1.778616500027411,-0.8067138905481915,-1.6042899045333228,0.09011573382996567,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.21440615544338357,2.596136262438205,0.12175448251162654,0.6065201023101452,-1.1555145615983378,0.15301100508827867,-2.3972018839891502,0.45984406883424556,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,0.8167483885125356,-0.09107218097239303,-0.51428752530657,0.009297339019232754,-0.43590826117893794,-0.6360363435663436,0.682890738977402,2.5443983795118403,-0.5543007948494578,-0.5745186791895069,-0.4553008972742839,1.5693674826960398,-0.9185947277776126,0.7929788244184839,1.5188836640650665,2.2514617717609795,2.1451816415421097,-0.51428752530657,1.0201626829533696,-0.9877693062177954,-0.303787854117314,0.5542099181825546,2.2342011612850494,1.1964900873490003,0.02566161901174243,1.992569263975948,1.9180197862656285,0.36168996784734275,0.8402742865808962,-2.2236327840032746,1.125611440557737,-0.9185947277776126,1.350128868152097,0.34734463722339803,1.0093338760985888,0.4042351666901161,0.45984406883424556,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,0.5409522516865753,1.6427531946624607,3.1003852237037637,-0.6153848387722859,-0.39751866108604983,0.7810014179820873,1.1358809033740525,0.6194206088649225,1.4758172511688186,1.7742210599427393 3193 Lysosomal lumen 27 35 4.663792050083275 3.1043508947892207e-06 P50897,Q14108,P10253,P38571,P07602,Q9NZJ7,Q8NHP8,O14773,O00584,P38435,O43681,Q13510,P04062,Q8IV08,Q9UMR5,P13473,P07686,P17900,P16278,P11117,P10619,P15586,P06865,Q99538,P61916,P06280,P54802 Localization GO Cellular component msigdb_gocc 8,9,145,526,20,148,21,150,285,157,557,45,53,184,188,72,584,79,82,85,98,225,224,365,491,244,126 285,765,150,557,53,591,244,224,20,584,1413,145,98,85,2351,72,1258,225,82,79,157,526,1035,8,126,491,45,9,184,2148,21,365,1066,148,188 1.413939040620315,0.48718206135466036,1.945483805688231,0.8048943132507087,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,2.762496989040066,0.7568588077238091,0.009297339019232754,1.9658133945446885,2.1872987787678158,2.2342011612850494,-0.5342242617338631,2.291063262623579,0.1059833465335269,1.6185951277994044,2.2399742438327923,2.2457277457630314,1.9041316359550924,0.8751148153965543,0.2445587153188426,3.0232917146470886,2.095763221365341,0.9207519138862322,2.5348046058833917,3.0232917146470886,1.7891089124911725,-0.39751866108604983,2.7541860634576008,1.176476578042439,0.22952714396117282,1.9590621281540601,1.7816796524116962 3193 Vacuolar lumen 33 63 4.61099081011274 4.007542562689537e-06 Q9BTY2,Q9H7Z7,P50897,Q14108,Q92820,P38571,P10253,P53634,P07602,Q9NZJ7,Q8NHP8,O14773,P38435,O00584,Q13217,O43681,Q13510,Q96CS3,P04062,Q8IV08,Q9UMR5,P13473,P07686,P17900,P16278,P11117,P10619,P15586,P06865,Q99538,P61916,P06280,P54802 Localization GO Cellular component msigdb_gocc 257,393,8,9,529,526,145,402,20,148,21,150,157,285,549,557,45,560,53,184,188,72,584,79,82,85,98,225,224,365,491,244,126 285,765,150,557,888,53,591,244,224,1522,2368,20,584,1413,145,98,85,2351,1895,72,1258,225,82,79,2880,2138,3030,157,526,1035,2624,8,2920,2684,402,1086,126,2584,2316,491,2042,1745,2639,549,45,9,1751,184,2148,21,529,560,2569,1295,365,1025,257,1066,393,2984,148,188,2635 1.413939040620315,0.48718206135466036,1.945483805688231,0.8048943132507087,0.36168996784734275,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,-0.05719278632694883,-0.5543007948494578,2.762496989040066,0.7568588077238091,0.009297339019232754,1.9658133945446885,2.1872987787678158,2.2342011612850494,-0.5342242617338631,-0.2671646500903092,2.291063262623579,0.1059833465335269,1.6185951277994044,2.2399742438327923,2.2457277457630314,-1.0585470825916556,-0.39751866108604983,-1.3852918433246575,1.9041316359550924,0.8751148153965543,0.2445587153188426,-0.7415449896710221,3.0232917146470886,-1.1309875400384923,-0.8067138905481915,1.0735225288658525,0.21440615544338357,2.095763221365341,-0.6988844633124501,-0.51428752530657,0.9207519138862322,-0.3409024311136362,-0.177690185818539,-0.7631090610942425,0.8285415486462114,2.5348046058833917,3.0232917146470886,-0.177690185818539,1.7891089124911725,-0.39751866108604983,2.7541860634576008,0.8751148153965543,0.8048943132507087,-0.6777844648834328,0.09011573382996567,1.176476578042439,0.25950170179577764,1.510343999684222,0.22952714396117282,1.1152930343193794,-1.2555878176142559,1.9590621281540601,1.7816796524116962,-0.7415449896710221 3193 Endoplasmic reticulum 200 464 4.591638606652763 4.397794185928561e-06 P43307,Q9BQE5,P24390,Q13724,P51571,P61019,Q14108,P98194,P80303,Q9Y394,P09601,O43731,O95197,Q02818,Q8N0U8,P30519,Q16611,Q32P28,Q13217,Q9P2W9,Q9Y680,Q5J8M3,Q9NZ01,O75915,Q13510,O43681,Q96CS3,Q99720,Q9UGP8,P04062,O15173,Q14849,Q9NQC3,O14880,Q15363,Q9H6V9,Q8WXH0,O75844,P51648,Q07065,Q8TCT9,Q15392,O60725,Q8TB61,P67812,Q9Y3B3,P10619,P37268,Q86UE4,Q15800,Q9Y5M8,Q06136,Q9BV10,Q9HD20,Q15629,P27105,Q96G23,Q9Y282,Q96A57,Q96KC8,O95470,Q70UQ0,Q15125,P52292,Q16880,O75503,Q5BJF2,Q9BUN8,Q7L0J3,Q9BRK5,Q03518,A1L0T0,Q96GC9,P38435,Q9NZ08,Q6ZXV5,Q8N511,Q9BRR6,P84157,Q16850,Q86YN1,Q96A33,Q96RL7,Q5VUD6,Q96PC5,Q8NF37,Q9NWM8,Q9Y4P3,Q8IV08,Q14257,P35613,Q9UMX5,P16615,Q9UBV2,P30536,Q9P035,P46977,Q6NUM9,P04035,Q14739,Q92542,Q969V3,Q9BUR5,Q12981,Q9NPA0,O75845,P39687,Q6NUQ4,O15260,O76024,P16435,Q9Y3E0,O15269,Q13190,P57088,Q9BTY2,O00264,P50402,Q9UKR5,Q9UQB8,Q8NHH9,P62942,P04439,Q01105,Q8N5M9,Q8WVQ1,O00584,Q53GQ0,Q92604,Q9UBR2,P48723,Q14534,Q99640,O00165,P49755,P27824,Q2TAA5,Q99735,O43852,Q9UBU6,Q15005,Q15904,Q8NBQ5,Q96HY6,Q9H3N1,P51572,Q96AY3,P07099,P55327,Q86UL3,Q86XL3,Q9BT22,Q8NHP6,O60476,Q9UHB9,O15258,Q99797,P05067,Q13641,Q9H490,P05023,Q8N2K0,P49458,O95674,Q9UM00,Q9UBM7,Q8IY95,P53634,Q96S66,Q86YV9,Q9BVK6,P35610,O00767,Q9Y320,Q9UNK0,Q96LJ7,P61026,Q00765,Q99442,P52789,Q6UWP7,P49257,Q96AG4,Q9BTV4,Q92643,Q8TCJ2,P13674,O14653,Q9NTJ5,Q9BU23,Q8TDW0,Q6NUQ1,O95864,Q9Y3A6,Q9UBF8,Q9BVC6,P04843,P61916,P42345,P10321 Localization GO Cellular component msigdb_gocc 0,1,2,511,519,520,9,522,14,531,17,26,27,29,30,32,544,545,549,39,40,550,556,551,45,557,560,50,571,53,56,58,59,562,61,62,575,67,71,73,80,84,87,89,94,95,98,99,102,107,108,110,111,113,114,115,118,119,121,125,128,130,131,138,140,139,144,147,149,151,152,153,156,157,159,160,161,164,165,170,171,174,178,177,180,181,182,183,184,186,192,194,196,198,200,203,204,207,205,210,211,212,213,223,239,238,240,243,245,247,248,250,252,253,255,257,258,261,266,269,271,276,275,278,279,283,285,286,289,293,296,297,298,303,304,311,312,314,315,320,322,323,324,326,329,327,328,331,333,334,335,342,340,346,349,355,359,360,361,366,363,371,374,377,385,400,399,402,403,412,415,410,416,423,429,426,430,431,432,435,441,447,458,460,468,467,464,462,486,485,484,483,482,498,496,495,490,491,500,499 666,153,844,303,1466,258,1249,2134,285,416,2486,462,562,1104,715,2033,56,355,245,252,1198,2846,1123,782,2542,918,716,2250,557,26,315,1125,346,1555,783,1705,87,756,1961,980,2424,903,139,2827,717,67,238,551,247,2576,1254,651,2036,1015,2073,2651,27,1647,2004,1302,128,2182,1521,1048,377,1763,482,2878,877,888,1304,205,53,275,1356,490,815,363,360,3087,785,331,684,2005,1927,17,2007,499,98,2997,1651,1597,464,1256,2830,1443,1258,248,196,3073,1966,960,1177,1445,3081,2288,2309,1931,3066,2620,1969,2,2958,2184,2849,1932,115,2906,1562,3117,2185,311,2138,2907,1473,1474,2037,32,200,3091,2464,1202,1260,1156,410,192,2356,1563,99,157,1448,240,500,1081,0,1158,2745,1359,204,1053,655,685,296,1602,1307,447,374,304,261,1159,670,519,327,71,1085,138,1799,435,2962,2659,402,2604,2584,2218,333,2315,2375,255,2899,2376,2163,1655,2434,520,430,1055,2851,1680,941,658,491,1390,1831,1450,1712,757,1263,1867,758,2114,2813,276,3153,2934,94,14,1803,906,2358,165,522,431,278,2471,1534,29,1451,152,1607,110,2013,73,1092,605,964,1452,2437,574,2499,625,223,1393,253,549,45,1425,2381,1807,361,511,9,880,186,2018,868,297,1207,1429,210,58,2167,2225,322,893,752,2560,1937,131,759,2779,61,986,84,3144,2294,1632,114,2855,1610,788,107,323,544,2326,170,140,312,545,286,2971,144,550,613,177,743,599,207,483,243,1209,441,2120,160,130,149,600,660,1136,102,334,733,335,171,412,823,184,2330,1163,640,399,30,946,371,161,1269,279,909,1270,1432,324,2148,989,181,626,271,340,2273,89,689,896,467,2021,80,484,1433,610,1139,2055,734,283,575,211,1211,289,468,1839,2611,992,1401,212,174,121,458,328,560,118,156,898,326,125,426,180,178,663,403,2734,432,3151,298,50,314,359,1,151,164,858,1026,342,460,257,485,147,213,111,495,2770,415,826,1324,2391,859,664,764,1780,930,329,1045,366,778,2100,62,932,827,726,113,735,860,239,59,594,486,2450,842,1376,182,2173,753,997,556,159,203,1170,1493,1353,1698,39,2101,496,400,293,2392,320,198,2894,571,349,2478,266,3183,385,194,2877,429,2479,1618,269,1497,119,1673,1408,423,531,498,95,250,2995,1102,183,108,3159,1220,1439,40,1854 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3193 Mitochondrion organization 92 189 4.544154480541825 5.51561981865234e-06 Q5JRX3,Q9Y2R0,O60830,Q9NS69,Q9NX14,O43676,Q8N4H5,P14406,O96008,Q99595,Q69YU5,Q9UDX5,Q5TC12,P78310,Q96A26,Q16611,O75306,Q13505,Q8N2A8,P45880,P21796,P04062,Q96CU9,Q9NVT9,Q9UJZ1,Q15070,Q9H061,O75431,P17152,Q9Y5L4,O14925,Q3ZCQ8,Q9P0J0,Q8N183,P02545,Q9Y6C9,Q7Z3C6,P51970,Q9Y4W6,Q9BSK2,P50851,P47985,O75153,O43819,Q96RL7,O95202,Q9BRT2,P30536,Q9UII2,P02786,Q8NE86,Q9BUR5,O95429,Q8IWA4,Q6DKK2,O60313,Q15388,Q9H3K2,Q10713,P12235,Q5XKP0,Q9NUQ9,Q9H4A6,Q9NVI7,P05141,Q9Y512,O14737,Q9GZY8,O00165,Q5T9A4,Q16891,P51572,Q96TA2,Q6UXV4,Q8WWC4,Q99797,O43615,Q53H12,Q99623,O95831,O75880,P55786,O95168,Q9NVH1,P52789,P49257,Q8NAN2,Q9NX63,Q16706,Q9BWH2,Q9Y5J9,Q9Y371 Processes and pathways GO Biological process msigdb_gobp 512,4,5,10,530,16,15,18,525,19,22,28,538,536,31,544,543,36,559,48,51,53,60,576,577,65,68,583,592,602,92,639,129,641,643,143,660,656,677,162,670,679,172,175,178,190,712,200,730,209,724,213,718,218,219,221,232,234,236,259,260,265,268,277,284,290,294,299,303,309,318,327,348,352,357,359,376,387,388,389,395,396,404,408,435,447,457,461,465,479,488,487 1121,303,1279,1013,2540,1249,294,92,2649,716,376,16,175,221,5,172,2212,876,543,1222,583,2072,1557,2306,395,1152,769,404,190,847,2636,718,2829,389,525,643,209,53,2955,1356,284,1413,1622,2428,2458,1255,259,18,592,2287,51,3117,2959,2930,2678,2373,200,2832,786,3031,1079,2465,2706,1081,48,679,2187,2039,447,2467,2432,670,327,656,435,2111,396,2376,2963,536,1868,1605,808,236,36,1807,2224,868,65,1288,232,2168,742,544,465,1507,1002,318,3167,639,387,512,309,538,260,22,219,352,2439,660,1112,968,218,969,1137,1718,1662,641,559,15,928,1269,457,724,2874,1368,2021,357,1062,881,31,60,1190,949,178,348,1909,3151,1295,19,388,2839,359,712,910,162,2242,2201,213,479,1213,299,1951,68,234,268,931,1327,2595,1244,10,1954,265,408,277,576,2027,530,461,1848,129,1884,3005,28,1406,730,577,862,4,875,487,2647,1195,677,290,488,602,143,935 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3193 Mitochondrial protein containing complex 60 145 4.536905385772342 5.708570133711177e-06 Q9P0J0,Q567V2,P12235,O60830,Q9UDW1,Q5XKP0,Q53H12,P82933,Q9NS69,Q99623,Q9NX14,O43676,Q8N4H5,P14406,O96008,Q99595,P51970,Q9HCC0,O95168,P09669,Q9NVH1,Q9Y4W6,P05141,O75306,Q9Y512,P08574,Q13505,O14949,P47985,P06576,P21912,Q9BRJ2,Q8IYU8,Q9BPX6,O75964,P54098,P56385,P21796,P12236,Q96CU9,Q16891,P00403,O75431,Q9NX63,Q7Z7H8,P24539,Q9Y5L4,Q9BUR5,Q8IWA4,O00330,O14925,P22695,Q6UXV4,Q9Y5J9,Q15388,P56134,P13073,Q96IX5,P40939,Q3ZCQ8 Localization GO Cellular component msigdb_gocc 129,3,259,5,6,260,387,521,10,388,530,16,15,18,525,19,656,534,404,652,408,677,284,543,290,668,36,37,679,552,553,302,425,301,47,686,305,51,179,60,318,195,583,461,466,83,602,213,218,603,92,97,352,488,232,618,109,637,631,639 2540,603,1174,832,92,37,956,16,1077,5,876,543,958,583,1557,1281,47,1106,1152,404,1963,847,525,195,284,552,2076,668,2183,796,652,2579,1153,1523,259,179,109,18,770,922,3040,981,51,553,1826,97,83,1333,2959,2678,1795,1284,786,983,2465,631,679,2932,1001,3049,2866,1531,1360,656,1183,2112,686,2218,618,305,1421,2410,1533,1340,1310,521,1363,1574,36,943,232,1507,1002,318,639,387,3,895,260,790,352,1477,2231,466,218,1718,425,15,1719,2121,724,2021,1238,1212,60,2567,2695,637,3191,19,388,2839,301,302,213,800,972,1726,704,802,2824,1327,534,1374,10,408,530,461,1377,1514,129,861,6,862,1463,1782,912,2344,1551,1031,677,290,488,602,935 -0.6777844648834328,0.7201675789757652,0.15301100508827867,0.4182557487269513,2.2109109040904884,2.58685650649295,0.30380731745916084,2.850934877568107,0.21440615544338357,3.1165747016179965,0.3759530057373177,0.8402742865808962,0.30380731745916084,0.7568588077238091,-0.07407874008591195,0.09011573382996567,2.515439795372476,0.19919490676105286,0.1684982022009186,1.0629537868319574,-0.303787854117314,0.4042351666901161,0.8751148153965543,1.751667447018552,1.4228948856937176,0.8167483885125356,-0.3596472519831671,0.6194206088649225,-0.43590826117893794,0.45984406883424556,0.6322515068949177,-0.6988844633124501,0.1684982022009186,-0.05719278632694883,1.5017677751833673,1.803880161059405,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,-1.4118743308181245,0.2891251966313216,2.5007588066882245,0.8167483885125356,-0.23102262249362931,2.1932323689347277,2.2399742438327923,0.05808732403364699,-1.2051532199617174,-0.8067138905481915,-0.213128942203161,0.09011573382996567,0.4735513630461408,0.2891251966313216,-0.6153848387722859,0.6703324293561015,0.6065201023101452,-1.1555145615983378,0.27435692511880505,-1.4386772460322241,-1.0347727466327314,-0.05719278632694883,0.04192461851956566,0.6322515068949177,0.15301100508827867,-0.3785188752723304,0.5935493889180543,-0.4553008972742839,0.6953823294342337,1.3408498426869389,0.009297339019232754,-0.5745186791895069,-0.05719278632694883,0.05808732403364699,0.07415070895816572,0.8866106862369233,0.04192461851956566,-0.07407874008591195,2.596136262438205,0.3184040786732402,1.6023224295792171,-0.04041324981336907,0.27435692511880505,1.293823383957412,0.6577068359941382,1.125611440557737,3.17018189671295,0.36168996784734275,1.5017677751833673,0.4735513630461408,1.2064269794639189,-0.023739075165896593,-0.4553008972742839,0.9543830980982788,1.6586937760640963,-0.16014273539632354,1.0201626829533696,2.9120109684113684,-0.16014273539632354,-0.3785188752723304,0.5542099181825546,-0.32228307221127694,0.12175448251162654,0.1374300649717309,2.356841664788679,-0.6777844648834328,-0.8067138905481915,0.6703324293561015,-6.137125425808874,2.8113998714497686,1.125611440557737,-0.9877693062177954,1.350128868152097,1.350128868152097,1.682361685022864,0.45984406883424556,0.30380731745916084,-0.16014273539632354,0.5805078633245453,0.45984406883424556,-0.9645358333127365,0.07415070895816572,0.863560440465855,0.04192461851956566,3.0024397548003465,1.0629537868319574,0.8751148153965543,0.9654822230844401,0.04192461851956566,-0.04041324981336907,2.0831876730587275,0.4042351666901161,3.1003852237037637,0.4042351666901161,-0.007169221259632773,-0.1953518618147444,0.34734463722339803,-0.51428752530657,-0.05719278632694883,0.25950170179577764,0.6194206088649225,1.4049437781239236,0.9320183829658302,0.7324623353077244,0.3329162614491058 3193 Organic anion transport 35 45 4.536162785825124 5.728696910178854e-06 P12235,Q9H2D1,Q02978,Q9Y619,P07602,Q7L0J3,Q9NZJ7,P53985,P05141,Q14728,P08195,Q96NB2,Q6NUK1,Q9UJS0,O75915,P55011,Q08722,P12236,Q9H2J7,Q15758,P53007,Q9UBX3,Q9Y6M7,Q9HC21,O43808,Q9BQT8,Q9H936,Q9H9B4,Q8TB61,O75746,P28288,Q8TDW0,P11166,O60831,Q99808 Processes and pathways GO Biological process msigdb_gobp 259,7,644,267,20,149,148,407,284,411,417,546,419,169,551,558,306,179,705,565,440,57,189,319,444,197,593,601,89,350,473,484,612,489,372 2346,2031,444,489,350,551,692,284,1078,20,417,612,259,179,2460,473,833,866,440,407,558,2555,644,306,411,752,565,419,1209,149,89,484,546,372,197,7,705,593,601,319,148,57,169,267,189 -0.5342242617338631,-0.3409024311136362,0.9765264378161742,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.5805078633245453,1.4228948856937176,0.21440615544338357,2.762496989040066,1.0416622545332883,0.7078077588474234,1.5017677751833673,1.803880161059405,-0.6153848387722859,0.9432286304255554,0.4182557487269513,0.39013449402256833,0.9875161701203701,1.0629537868319574,0.8048943132507087,-0.6777844648834328,0.6450133877649504,1.3408498426869389,1.05233382643295,0.5142163574940924,0.7929788244184839,1.0416622545332883,0.1374300649717309,1.952285648216789,2.2225958317358057,0.9320183829658302,0.8402742865808962,1.1663992693165688,1.751667447018552,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,1.293823383957412,1.9590621281540601,2.39928112695771,1.854681789652418,1.4758172511688186,1.7742210599427393 3193 Vacuolar membrane 44 125 4.532337641870225 5.833450908765414e-06 Q9UIQ6,P61019,Q14108,P42785,Q6IAA8,O75503,Q8WTV0,Q8IY95,P10253,P07602,Q9NZJ7,Q86YV9,Q9H2V7,Q96GC9,Q8N511,P08195,Q9UNK0,Q96RL7,P04062,Q8NF37,Q8IV08,Q14849,P13473,Q07065,Q93050,P11279,Q92542,P11117,O75955,Q9Y487,O15400,O95721,P10619,Q9Y371,P42892,Q15043,Q9HC07,Q13137,P27105,O15260,Q9BTU6,P42345,Q9NQX7,P51798 Localization GO Cellular component msigdb_gocc 516,520,9,136,523,139,141,399,145,20,148,412,155,156,161,417,429,178,53,181,184,58,72,73,208,206,211,85,338,88,345,472,98,487,100,241,116,504,115,245,507,500,127,383 1013,916,2033,245,345,2366,1253,623,2002,2348,139,338,2702,472,749,53,815,1522,20,1387,417,1559,1927,1677,145,98,85,2351,206,72,1155,693,2547,3066,115,1972,865,962,2998,1448,866,500,136,100,694,2683,1530,890,3161,383,1085,1054,2315,1038,2376,520,1055,1361,2407,1532,818,2589,3025,73,1092,2193,2116,504,9,58,241,986,532,523,789,660,412,184,399,161,181,2874,141,2333,1271,211,208,1063,1511,824,1723,1064,156,949,178,1487,883,507,3189,1616,1100,859,1881,1351,155,2842,827,116,1147,2875,127,1148,148,2674,1493,1298,1996,2151,516,2177,1959,429,714,487,88 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3193 Mitochondrial envelope 143 305 4.510504247154668 6.467370641471959e-06 Q567V2,Q9Y2R0,O60830,Q9UDW1,Q9H2D1,P82933,Q9NS69,Q9NX14,O43676,P09601,P14406,O96008,Q99595,Q8N4H5,Q69YU5,Q8WY22,O43169,Q9UDX5,Q96A26,O75306,Q16611,Q96NB2,Q13505,O14949,Q00325,P06576,P21912,Q13423,Q8N2A8,P45880,O75964,P21796,Q9NR28,Q9NZ45,Q9UBX3,O75208,Q96CU9,Q9NVT9,Q9UJZ1,Q15070,Q9H061,Q70HW3,O75431,P17152,Q9H936,P24539,Q9Y5L4,Q9H9B4,P22830,O14925,P22695,P56134,P13073,Q7KZN9,Q96IX5,P40939,Q3ZCQ8,Q9P0J0,Q8N183,Q8NBU5,Q9Y277,Q02978,Q9Y6C9,P51970,Q9NZJ7,P09669,Q9Y4W6,Q9H2V7,P08574,Q9BSK2,Q9NQZ5,Q6P4A7,P23786,Q9UJS0,O43819,Q96RL7,P12236,O95202,O43772,P00403,Q9BQT8,P30536,Q9BUR5,Q8IWA4,Q6DKK2,O60313,P57105,Q12981,Q15388,Q9H3K2,Q10713,O00264,P12235,Q5XKP0,Q9Y619,Q9H4A6,Q9NVI7,Q9HCL2,P05141,O00584,Q8NBN7,Q9Y512,Q9GZY8,Q9BRJ2,Q9BPX6,Q9BXK5,O00165,P56385,Q5T9A4,P53701,Q16891,Q9HC21,Q96AY3,Q96TA2,O75746,Q6UXV4,Q8WWC4,Q6PI78,O43615,O95674,Q96TC7,Q53H12,Q99623,O95831,O75880,O75027,O95168,Q9NVH1,Q6NUK1,Q9Y320,Q8IYU8,P52789,P53007,P49748,Q8NAN2,Q9NX63,Q7Z7H8,Q9BWH2,O15228,Q9Y5J9,Q9Y371,Q9UBF8,P42345 Localization GO Cellular component msigdb_gocc 3,4,5,6,7,521,10,530,16,17,18,525,19,15,22,23,25,28,31,543,544,546,36,37,554,552,553,43,559,48,47,51,570,54,57,563,60,576,577,65,68,77,583,592,593,83,602,601,596,92,97,618,109,112,637,631,639,129,641,647,135,644,143,656,148,652,677,155,668,162,163,166,167,169,175,178,179,190,191,195,197,200,213,218,219,221,222,223,232,234,236,258,259,260,267,268,277,281,284,285,287,290,299,302,301,307,303,305,309,317,318,319,328,348,350,352,357,375,376,377,384,387,388,389,395,397,404,408,419,423,425,435,440,455,457,461,466,479,471,488,487,496,500 303,2540,258,1249,832,285,3169,1785,92,37,471,2650,25,716,376,16,191,175,221,1555,5,397,563,876,543,1222,958,583,2072,1557,739,350,395,1281,47,1106,1152,769,404,1963,190,847,1048,377,389,525,888,195,284,552,3108,668,2183,1622,17,652,1153,2458,3138,259,179,2740,109,18,770,922,592,3073,960,2252,3040,981,51,553,2704,97,596,1969,167,83,1333,2959,2723,2678,200,1795,1284,1202,2355,786,2038,983,1032,2465,631,500,1052,48,679,2932,1001,455,3049,2374,923,1531,656,435,1183,2524,440,317,2188,1088,2218,618,305,222,818,1421,1339,2410,1533,1340,1310,521,554,3076,1362,644,236,1133,223,2747,1363,1574,43,36,1807,943,2018,868,65,1288,232,2168,821,544,1507,1002,318,639,387,3,895,309,2019,260,22,219,2856,419,790,166,375,1396,809,352,77,112,2231,1905,466,218,969,1137,425,1811,641,559,1097,15,928,1269,1719,2121,457,287,647,1545,724,1907,2021,357,23,2818,1238,856,1239,881,31,1212,328,1024,948,60,2567,2127,776,1190,637,546,178,348,384,3151,1295,19,388,301,812,197,302,712,162,1117,2242,2201,213,3189,479,307,800,972,1726,1243,1489,704,299,68,1007,7,155,802,234,268,931,593,2806,601,2824,1512,1327,319,281,727,2595,1244,163,570,2448,1374,10,842,1328,408,277,576,2027,530,461,1377,54,148,1514,1848,129,861,496,57,6,28,1406,169,577,862,135,1463,4,1782,912,423,487,2344,1551,2647,1031,1409,677,290,488,602,267,143,935 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3193 Anion transmembrane transport 32 41 4.4672015319777385 7.924946551440826e-06 P12235,Q9H2D1,Q9Y277,Q9Y619,P53985,P05141,Q14728,P08195,Q96NB2,Q00325,Q9UJS0,O75915,P55011,P45880,P08183,Q9BXP2,P21796,P12236,Q15758,P53007,Q9UBX3,Q9Y6M7,Q9HC21,O43808,Q9BQT8,Q9H936,Q8TB61,O75746,Q8TDW0,Q9UHG3,O60831,P51798 Processes and pathways GO Biological process msigdb_gobp 259,7,135,267,407,284,411,417,546,554,169,551,558,48,176,433,51,179,565,440,57,189,319,444,197,593,89,350,484,105,489,383 444,489,350,551,284,1078,176,417,259,179,51,833,866,48,3161,383,440,407,558,554,644,1453,411,565,89,484,546,197,433,7,593,601,319,1147,57,105,169,135,2481,267,189 0.9765264378161742,0.9207519138862322,1.2064269794639189,0.8167483885125356,1.4228948856937176,0.21440615544338357,1.8112225085127378,1.0416622545332883,1.5017677751833673,1.803880161059405,2.5007588066882245,0.4182557487269513,0.39013449402256833,2.515439795372476,-2.3972018839891502,1.1358809033740525,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.8167483885125356,0.6450133877649504,-0.007169221259632773,1.05233382643295,0.7929788244184839,2.2225958317358057,0.9320183829658302,0.8402742865808962,1.751667447018552,1.0093338760985888,3.043830354362099,0.7446925671515504,0.7324623353077244,1.293823383957412,0.1838925440088085,2.39928112695771,2.175369810670554,1.854681789652418,2.051351117777622,-0.6153848387722859,1.4758172511688186,1.7742210599427393 3193 Intrinsic component of plasma membrane 51 76 4.404291555080489 1.0613013079030509e-05 Q9UIQ6,O00264,P12235,Q02978,Q8WTV0,O60637,P04439,P53985,P05141,P78310,Q15375,P11717,P20020,A0FGR8,Q00325,O43657,Q9UJS0,Q9UNK0,P55011,Q08722,Q9NR28,Q9H2J7,P27824,Q15758,Q12907,P35613,P16615,P51572,Q8NAN2,P17152,P11279,P02786,O96005,Q8NHP6,Q92542,Q8TAD4,Q99805,O43464,Q8TDW0,O95864,P05067,P11166,Q13641,Q99797,P05023,Q15043,Q8N2K0,Q99808,Q9BTU6,P27105,P10321 Localization GO Cellular component msigdb_gocc 516,258,259,644,141,13,275,407,284,536,674,669,291,666,554,38,169,429,558,306,570,705,311,565,574,192,196,327,457,592,206,209,81,340,211,86,343,716,484,482,360,612,361,359,363,241,371,372,507,115,499 666,258,1785,1892,2033,782,716,38,13,482,81,1304,209,275,363,1676,360,284,1078,499,612,206,669,259,196,592,1177,291,1155,115,311,833,786,192,1032,866,327,3161,407,798,558,536,554,644,306,574,1058,361,2225,241,2779,674,565,733,371,457,340,86,484,141,211,359,343,372,2786,507,3189,859,705,2715,570,1883,516,169,429,1465 0.6194206088649225,1.5017677751833673,-0.213128942203161,-0.2671646500903092,-0.3409024311136362,0.4735513630461408,0.5542099181825546,2.572831939044648,2.977706291199689,0.9320183829658302,2.2399742438327923,0.07415070895816572,1.6979807301199143,1.4495286247621895,1.176476578042439,-0.14270834812699967,1.1865067348823226,1.4228948856937176,0.21440615544338357,0.9094287765563077,0.7078077588474234,1.7057429944746445,0.6194206088649225,1.5017677751833673,1.751667447018552,0.7446925671515504,0.15301100508827867,1.3959088234962316,0.1684982022009186,2.132957634741071,1.3221664240422288,0.4182557487269513,0.4735513630461408,1.7592151429408447,0.2445587153188426,0.39013449402256833,1.2650915011001496,-2.3972018839891502,1.0629537868319574,0.45984406883424556,0.8048943132507087,0.8519470898097677,0.8167483885125356,0.6450133877649504,1.3408498426869389,0.7810014179820873,0.22952714396117282,1.1865067348823226,-0.4553008972742839,1.5693674826960398,-0.9185947277776126,0.6194206088649225,0.7929788244184839,0.5409522516865753,1.1663992693165688,0.9654822230844401,1.2359622824697312,2.2342011612850494,0.9320183829658302,1.9991966569128934,1.682361685022864,1.1964900873490003,1.2261627415331837,1.1663992693165688,-0.9185947277776126,0.9094287765563077,-5.5840666418038385,0.4042351666901161,0.5805078633245453,-0.8287583635800084,0.7929788244184839,-0.24903411518852805,0.8980485194817284,1.854681789652418,1.0201626829533696,-0.007169221259632773 3193 Membrane lipid metabolic process 24 34 4.393219680148743 1.1168416945706028e-05 O95470,Q53H12,P50897,Q16880,P07602,Q9NZJ7,Q8NBX0,Q9NZ01,Q13510,P04062,Q99735,Q8NCC3,Q9P035,P07686,P17900,Q92643,P16278,Q99805,P06865,Q9H490,Q06136,P06280,Q96G23,O15269 Processes and pathways GO Biological process msigdb_gobp 128,387,8,140,20,148,154,556,45,53,314,193,203,584,79,468,82,343,224,366,110,244,118,252 252,1198,716,756,128,53,591,244,224,20,584,82,79,2309,938,8,110,45,140,387,154,193,468,1401,118,663,314,343,366,753,556,148,203,1493 1.5188836640650665,0.1374300649717309,0.5542099181825546,0.5007368375870117,2.0894866813375814,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,2.762496989040066,0.7568588077238091,2.2399742438327923,2.2457277457630314,-0.51428752530657,0.3184040786732402,3.0232917146470886,2.1512615372917634,2.5348046058833917,2.0123785518790727,1.125611440557737,1.9318034306318732,1.7592151429408447,0.9543830980982788,0.02566161901174243,2.1268132851345656,0.6322515068949177,1.3127614347392678,1.2261627415331837,1.176476578042439,0.5142163574940924,0.8167483885125356,1.9590621281540601,1.7288431475403072,-0.023739075165896593 3193 Inorganic ion transmembrane transport 53 111 4.367303410714666 1.2578992976131076e-05 Q9UM00,P12235,Q99623,Q9UDW1,Q02978,P98194,O75027,Q96ES6,P62942,Q9Y4W6,Q96GC9,P05141,P08195,P08574,P46934,P20020,Q00325,P47985,P06576,Q13423,Q8IYU8,P55011,O75964,Q9BPX6,Q9BXP2,P56385,P21796,Q9H2J7,Q9UBX3,Q9Y6M7,Q9UJZ1,O95202,P21281,P00403,P16615,Q9H936,Q8NE86,P24539,Q8TAD4,Q8WWC4,Q9UHG3,P56134,P13073,P05023,Q7KZN9,Q9HD20,Q15043,Q9HC07,P27105,Q12959,P62258,Q6P4Q7,P51798 Processes and pathways GO Biological process msigdb_gobp 385,259,388,6,644,522,397,142,276,677,156,284,417,668,35,291,554,679,552,43,425,558,47,301,433,305,51,705,57,189,577,190,693,195,196,593,724,83,86,357,105,618,109,363,112,113,241,116,115,625,633,254,383 832,2346,1076,2488,397,876,1222,2072,1281,47,190,2426,195,363,1676,284,1078,552,1522,1387,417,668,1153,2403,259,109,196,1623,1501,291,981,693,2547,3065,51,83,1333,115,3117,2678,3091,1284,983,962,2998,1081,35,1227,679,2932,1181,3161,383,798,558,618,305,1361,941,633,276,2378,522,554,1605,644,2320,1423,2193,2499,625,43,2381,2412,2225,241,254,112,2330,425,2838,1991,724,86,357,1400,142,156,898,3151,388,2786,301,910,433,859,801,705,593,116,113,735,57,6,2478,105,2151,577,385,677,189 0.4182557487269513,-0.5342242617338631,0.21440615544338357,-0.6360363435663436,1.0945079100252835,0.3759530057373177,0.12175448251162654,-0.3596472519831671,0.09011573382996567,2.515439795372476,1.7667329517528663,-0.5948794930148794,1.751667447018552,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.21440615544338357,0.8167483885125356,-0.05719278632694883,0.02566161901174243,1.0416622545332883,0.6194206088649225,0.1684982022009186,-0.5745186791895069,1.5017677751833673,2.1512615372917634,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,-1.492956015355766,2.5007588066882245,2.2399742438327923,0.05808732403364699,2.132957634741071,-1.778616500027411,-0.8067138905481915,-1.6042899045333228,0.09011573382996567,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.21440615544338357,2.596136262438205,0.12175448251162654,0.6065201023101452,-1.1555145615983378,0.15301100508827867,-2.3972018839891502,1.1358809033740525,0.45984406883424556,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,0.8167483885125356,-0.09107218097239303,0.6450133877649504,-0.51428752530657,0.009297339019232754,-0.43590826117893794,-0.6360363435663436,0.682890738977402,2.5443983795118403,-0.5543007948494578,-0.5745186791895069,-0.4553008972742839,1.5693674826960398,1.5188836640650665,2.1451816415421097,-0.51428752530657,1.0201626829533696,-0.9877693062177954,-0.303787854117314,0.5542099181825546,2.2342011612850494,1.1964900873490003,0.02566161901174243,1.992569263975948,1.9180197862656285,0.36168996784734275,-2.2236327840032746,1.125611440557737,-0.9185947277776126,1.350128868152097,0.34734463722339803,1.0093338760985888,0.4042351666901161,0.45984406883424556,0.5805078633245453,0.7446925671515504,2.132957634741071,2.1451816415421097,0.5409522516865753,2.39928112695771,3.1003852237037637,-0.6153848387722859,2.175369810670554,-0.39751866108604983,0.7810014179820873,1.1358809033740525,0.6194206088649225,1.7742210599427393 3193 Cation transport 66 149 4.352738577796221 1.3444743483637112e-05 Q9UM00,P12235,Q99623,Q9UDW1,P98194,Q9Y619,O75027,Q96ES6,P62942,Q9Y4W6,Q96GC9,P05141,Q16611,P08195,Q96NB2,P46934,P08574,P20020,Q00325,P47985,P06576,Q13423,Q8IYU8,P55011,O75964,Q9BPX6,Q9BXP2,P56385,P21796,Q9H2J7,O15173,Q15758,Q9Y6M7,Q9UJZ1,O95202,P46459,O43772,Q9HC21,O75844,P00403,P16615,O43808,P30536,Q70HW3,Q9H936,P02786,P24539,Q9H9B4,Q8TAD4,Q15907,Q9NW15,Q8WWC4,P05067,P56134,P13073,P05023,Q7KZN9,Q9HD20,Q15043,Q9HC07,Q99808,P27105,Q12959,O76024,P62258,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 385,259,388,6,522,267,397,142,276,677,156,284,544,417,546,35,668,291,554,679,552,43,425,558,47,301,433,305,51,705,56,565,189,577,190,694,191,319,67,195,196,444,200,77,593,209,83,601,86,216,220,357,360,618,109,363,112,113,241,116,372,115,625,247,633,254 2301,1249,832,2346,999,56,1076,191,444,1125,2488,397,876,1222,2072,67,1281,47,247,190,2426,195,209,1730,363,1676,360,284,1078,1596,552,1522,2137,1387,417,668,1153,1792,2403,259,109,2352,196,1623,1501,291,981,693,2547,3065,51,83,1358,1333,115,3117,2678,200,3091,1284,865,1128,983,962,2998,1081,694,35,1227,679,2932,1181,3161,1085,798,558,618,305,1089,1361,941,633,276,2378,2555,522,554,1605,2589,1132,2320,1423,2836,2193,2499,625,43,1425,2381,2412,2225,241,2779,565,216,544,1002,254,77,112,2330,425,2838,1991,724,86,357,1400,142,156,898,546,3151,388,372,2786,301,910,433,859,801,705,593,601,116,319,113,735,220,6,2478,2151,577,385,2903,978,677,267,189 -0.51428752530657,0.1059833465335269,0.4182557487269513,-0.5342242617338631,0.27435692511880505,2.39928112695771,0.21440615544338357,1.7592151429408447,0.9765264378161742,0.1838925440088085,-0.6360363435663436,1.0945079100252835,0.3759530057373177,0.12175448251162654,-0.3596472519831671,2.329750012077,0.09011573382996567,2.515439795372476,1.5358542924197818,1.7667329517528663,-0.5948794930148794,1.751667447018552,1.6979807301199143,-0.177690185818539,1.176476578042439,-0.14270834812699967,1.1865067348823226,1.4228948856937176,0.21440615544338357,-0.09107218097239303,0.8167483885125356,-0.05719278632694883,-0.39751866108604983,0.02566161901174243,1.0416622545332883,0.6194206088649225,0.1684982022009186,-0.213128942203161,-0.5745186791895069,1.5017677751833673,2.1512615372917634,-0.5342242617338631,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,-1.492956015355766,2.5007588066882245,2.2399742438327923,0.04192461851956566,0.05808732403364699,2.132957634741071,-1.778616500027411,-0.8067138905481915,1.7364816398521126,-1.6042899045333228,0.09011573382996567,0.39013449402256833,0.1838925440088085,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.21440615544338357,0.5805078633245453,2.596136262438205,0.12175448251162654,0.6065201023101452,-1.1555145615983378,0.15301100508827867,-2.3972018839891502,0.21440615544338357,0.45984406883424556,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.21440615544338357,0.04192461851956566,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,-0.6777844648834328,0.8866106862369233,0.8167483885125356,-0.09107218097239303,-0.6988844633124501,0.1838925440088085,-0.51428752530657,0.009297339019232754,-0.9877693062177954,-0.43590826117893794,-0.6360363435663436,0.682890738977402,2.5443983795118403,0.009297339019232754,-0.5543007948494578,-0.5745186791895069,-0.4553008972742839,1.5693674826960398,-0.9185947277776126,0.7929788244184839,1.6586937760640963,0.8402742865808962,0.27435692511880505,1.5188836640650665,2.2514617717609795,2.1451816415421097,-0.51428752530657,1.0201626829533696,-0.9877693062177954,-0.303787854117314,0.5542099181825546,2.2342011612850494,1.1964900873490003,0.02566161901174243,1.992569263975948,1.9180197862656285,0.36168996784734275,0.8402742865808962,-2.2236327840032746,1.125611440557737,1.1663992693165688,-0.9185947277776126,1.350128868152097,0.34734463722339803,1.0093338760985888,0.4042351666901161,0.45984406883424556,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.132957634741071,1.293823383957412,2.1451816415421097,0.5409522516865753,1.6427531946624607,3.1003852237037637,-0.6153848387722859,-0.39751866108604983,0.7810014179820873,1.1358809033740525,-1.082506135737104,0.30380731745916084,0.6194206088649225,1.4758172511688186,1.7742210599427393 3193 Sphingolipid metabolism 14 26 4.3457391278895 1.3880746010608291e-05 O95470,P10619,P06865,P51648,Q16880,Q13510,P17900,Q06136,P16278,Q9NZJ7,P07602,P04062,P06280,Q96G23 Processes and pathways Reactome Pathways msigdb_reactome 128,98,224,71,140,45,79,110,82,148,20,53,244,118 666,252,1198,557,1647,128,53,244,224,20,584,98,1258,82,79,2309,71,110,45,140,1432,118,1026,753,148,1493 0.6194206088649225,1.5188836640650665,0.1374300649717309,0.8048943132507087,-0.12538587769838372,2.0894866813375814,2.4355304023078563,1.5526815978228736,1.6185951277994044,2.762496989040066,0.7568588077238091,2.1872987787678158,0.1059833465335269,2.2399742438327923,2.2457277457630314,-0.51428752530657,2.2966451596705606,2.1512615372917634,2.5348046058833917,2.0123785518790727,0.009297339019232754,2.1268132851345656,0.25950170179577764,0.5142163574940924,1.9590621281540601,-0.023739075165896593 3193 transporter 25 56 4.296677242691488 1.7337734884659284e-05 Q567V2,O60830,Q9H2D1,P52292,Q9Y619,Q8TEX9,Q99595,P53985,Q9H2V7,O43681,Q9NR77,P53007,Q9UJZ1,O43772,Q15070,O15397,Q99805,Q8N1F7,Q12769,Q92544,Q8NFH4,Q96P70,Q99808,Q9HD45,O43615 Functions Panther Protein class panther_protein_class 3,5,7,138,267,528,19,407,155,557,49,440,577,191,65,453,343,477,474,353,494,237,372,117,376 1103,1196,1151,916,2032,453,376,557,191,2543,5,1047,740,1157,1179,866,1602,2079,138,2404,1767,440,407,1898,721,2315,1308,941,474,2167,65,3,3026,945,477,494,1139,528,353,616,1723,237,1116,19,343,372,3018,7,155,1435,117,49,1590,577,754,267 0.19919490676105286,0.1374300649717309,0.1684982022009186,0.3329162614491058,-0.3409024311136362,0.9654822230844401,1.1461017884280336,0.8048943132507087,1.7592151429408447,-0.6777844648834328,3.1165747016179965,0.22952714396117282,0.5276212788728801,0.1684982022009186,0.15301100508827867,0.39013449402256833,-0.09107218097239303,-0.3596472519831671,2.0254641929604245,-0.5745186791895069,-0.1953518618147444,0.9875161701203701,1.0629537868319574,-0.2671646500903092,0.5542099181825546,-0.51428752530657,0.07415070895816572,0.3184040786732402,0.9432286304255554,-0.41664798954862137,2.3406400045953175,3.17018189671295,-1.3589269339837995,0.3184040786732402,0.9432286304255554,0.9207519138862322,0.1838925440088085,0.8751148153965543,1.2064269794639189,0.7078077588474234,-0.16014273539632354,1.5859138151123813,0.19919490676105286,2.8113998714497686,1.2261627415331837,1.1663992693165688,-1.3327768033414031,3.043830354362099,1.9249245939305628,0.009297339019232754,2.132957634741071,2.515439795372476,-0.07407874008591195,0.7810014179820873,0.5142163574940924,1.4758172511688186 3193 Active transmembrane transporter activity 42 69 4.292440123118042 1.767202151703451e-05 Q9P0J0,P12235,Q9UDW1,Q02978,P98194,O75027,Q96ES6,O43676,P51970,O95168,P53985,Q03518,P05141,O75306,P08195,P08574,P20020,Q00325,P47985,P06576,P55011,P08183,Q9BXP2,P12236,Q9H2J7,Q15758,P53007,Q9UBX3,Q9Y6M7,O95202,P21281,P00403,P16615,Q9H936,P28288,Q15388,P13073,P05023,Q7KZN9,Q9HD20,Q15043,P51798 Functions GO Molecular function msigdb_gomf 129,259,6,644,522,397,142,16,656,404,407,152,284,543,417,668,291,554,679,552,558,176,433,179,705,565,440,57,189,190,693,195,196,593,473,232,109,363,112,113,241,383 2540,832,16,397,876,543,958,1557,404,1963,190,847,195,363,1676,284,552,176,417,668,1153,259,179,109,196,3040,291,981,693,2547,473,2959,1284,833,962,2998,866,679,3049,3161,383,656,440,407,558,1361,522,554,644,152,241,232,565,1507,1002,112,724,142,433,705,593,113,2448,129,57,6,2151,189,935 -0.6777844648834328,0.4182557487269513,2.850934877568107,1.0945079100252835,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.0629537868319574,-0.303787854117314,1.7667329517528663,0.4042351666901161,1.751667447018552,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.8167483885125356,1.8112225085127378,1.0416622545332883,0.6194206088649225,0.1684982022009186,1.5017677751833673,1.803880161059405,2.1512615372917634,1.751667447018552,-1.4118743308181245,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,0.9432286304255554,-1.2051532199617174,0.09011573382996567,0.4182557487269513,0.30380731745916084,-1.3068387009445777,0.39013449402256833,0.6065201023101452,-1.4386772460322241,-2.3972018839891502,1.1358809033740525,0.6322515068949177,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.04192461851956566,0.8866106862369233,0.8167483885125356,0.6450133877649504,1.9386564503168657,1.5693674826960398,1.6023224295792171,0.7929788244184839,-0.04041324981336907,0.27435692511880505,2.1451816415421097,0.5542099181825546,1.992569263975948,1.0093338760985888,0.5805078633245453,0.7446925671515504,2.1451816415421097,-0.5948794930148794,2.0831876730587275,2.39928112695771,3.1003852237037637,-0.39751866108604983,1.7742210599427393,0.3329162614491058 3193 Anion transmembrane transporter activity 36 46 4.272118263076186 1.936248350142833e-05 P12235,Q9H2D1,Q9Y277,Q9C0H2,Q9Y619,Q96S66,P53985,P05141,Q14728,P08195,Q96NB2,Q6NUK1,Q9UJS0,O43681,P55011,P45880,Q9BXP2,P21796,P12236,Q15758,Q9UBX3,P53007,Q9Y6M7,Q9HC21,O43808,Q9BQT8,Q9H936,Q9H9B4,Q8TB61,Q9NW15,O75746,Q8TDW0,P11166,Q15043,Q99808,P51798 Functions GO Molecular function msigdb_gomf 259,7,135,11,267,403,407,284,411,417,546,419,169,557,558,48,433,51,179,565,57,440,189,319,444,197,593,601,89,220,350,484,612,241,372,383 3036,2346,557,444,350,284,417,2722,612,259,179,51,833,866,48,3161,383,440,407,558,644,411,241,565,3026,419,1209,89,484,546,403,372,197,433,11,7,593,601,319,220,57,169,135,267,2211,189 -1.4118743308181245,-0.5342242617338631,0.8048943132507087,0.9765264378161742,1.2064269794639189,1.4228948856937176,1.0416622545332883,-0.8509667351664257,0.7078077588474234,1.5017677751833673,1.803880161059405,2.5007588066882245,0.4182557487269513,0.39013449402256833,2.515439795372476,-2.3972018839891502,1.1358809033740525,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.6450133877649504,1.05233382643295,1.5693674826960398,0.7929788244184839,-1.3589269339837995,1.0416622545332883,0.1374300649717309,2.2225958317358057,0.9320183829658302,0.8402742865808962,1.0735225288658525,1.1663992693165688,1.751667447018552,1.0093338760985888,2.984818292512709,3.043830354362099,0.7446925671515504,0.7324623353077244,1.293823383957412,1.6427531946624607,2.39928112695771,1.854681789652418,2.051351117777622,1.4758172511688186,-0.43590826117893794,1.7742210599427393 3193 Protein targeting 43 114 4.255773055083053 2.083279407028016e-05 P43307,Q5JRX3,Q9P0J0,P40855,Q53H12,O60830,O75381,O95831,Q14108,Q9NS69,P55786,Q8N4H5,O96008,Q99595,Q9Y512,P46934,O14737,Q9GZY8,O43681,Q96RL7,O00165,Q99442,Q9UGP8,P49257,Q15005,P13473,P30536,P51572,O60725,O14925,Q9UHB9,P57105,P46379,Q9Y5J9,Q9Y371,Q99797,Q15388,Q9Y5M8,Q10713,Q15629,P27105,P49458,O43615 Processes and pathways GO Biological process msigdb_gobp 0,512,129,386,387,5,263,389,9,10,396,15,525,19,290,35,294,299,557,178,303,432,571,447,322,72,200,327,87,92,349,222,351,488,487,359,232,108,236,114,115,374,376 1729,303,1279,1013,916,294,2031,92,767,716,376,557,919,87,5,263,2072,2576,1152,769,2636,718,2829,389,525,1413,2005,3064,2458,2351,72,2287,1155,115,2677,3117,200,2908,564,1972,2832,2550,386,0,351,35,447,374,2467,890,327,396,2375,222,2899,1655,2434,941,2405,633,2686,2041,2963,1605,236,2499,9,322,232,114,2168,742,639,387,512,2797,2913,945,2440,968,2798,761,15,928,178,2534,432,1909,1350,19,359,299,1952,1327,1244,10,1954,129,1884,3005,571,349,2478,730,2341,831,1959,714,487,2481,290,488,602,108 -0.177690185818539,1.3408498426869389,0.09011573382996567,0.25950170179577764,0.3329162614491058,1.38683389940539,-0.3409024311136362,2.2109109040904884,0.48718206135466036,0.5542099181825546,1.1461017884280336,0.8048943132507087,0.3329162614491058,2.2284083926639537,3.1165747016179965,1.4845046522176364,-0.3596472519831671,-0.6988844633124501,0.1684982022009186,0.48718206135466036,-0.7631090610942425,0.5542099181825546,-0.9877693062177954,1.1152930343193794,0.8751148153965543,0.009297339019232754,-0.32228307221127694,-1.492956015355766,-0.6153848387722859,-0.5342242617338631,2.291063262623579,-0.494489054305589,0.1684982022009186,2.132957634741071,-0.8067138905481915,-1.778616500027411,1.7364816398521126,-1.1066521830470757,0.7929788244184839,-0.303787854117314,-0.9877693062177954,-0.6777844648834328,1.125611440557737,3.2740327620941194,1.2064269794639189,2.596136262438205,0.9765264378161742,1.1562744576555442,-0.6153848387722859,0.36168996784734275,1.2650915011001496,1.1049253152266847,-0.5543007948494578,1.6266810625618235,-1.082506135737104,-0.12538587769838372,-0.5948794930148794,0.3184040786732402,-0.5745186791895069,0.6703324293561015,-0.8067138905481915,-0.3409024311136362,-1.2051532199617174,-0.09107218097239303,1.5859138151123813,-0.6360363435663436,3.0232917146470886,1.284289708677259,1.6023224295792171,2.1390803803002107,-0.41664798954862137,0.5276212788728801,0.6577068359941382,1.125611440557737,0.8980485194817284,-0.9414783391764264,-1.1066521830470757,0.3184040786732402,-0.5948794930148794,0.30380731745916084,-0.9414783391764264,0.5007368375870117,2.9120109684113684,0.3329162614491058,1.8112225085127378,-0.656835659642823,1.0093338760985888,-0.2671646500903092,0.05808732403364699,2.8113998714497686,1.1964900873490003,1.38683389940539,-0.28541547461577405,0.07415070895816572,0.12175448251162654,3.0024397548003465,-0.28541547461577405,2.0831876730587275,-0.24903411518852805,-1.3068387009445777,0.7929788244184839,1.216317751801572,-0.6153848387722859,0.5542099181825546,-0.51428752530657,0.4321969562595515,-0.28541547461577405,0.5673949130081869,0.9320183829658302,-0.6153848387722859,1.4049437781239236,0.9320183829658302,0.7324623353077244,2.163357703140536 3193 Metal ion homeostasis 38 79 4.217887133113071 2.466021951175179e-05 Q96TC7,Q9UM00,P98194,O75880,O75027,P09601,P62942,Q7L0J3,Q8NE01,P30519,Q16611,Q8N511,P20020,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9BXP2,O95202,Q9UJZ1,Q16891,Q15904,P16615,P51572,P07686,P02786,Q8TAD4,Q9Y487,Q8WWC4,P05067,P05023,Q9HD20,Q15043,Q9HC07,Q9Y5X3,O76024,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 384,385,522,395,397,17,276,149,280,32,544,161,291,425,558,174,175,301,433,190,577,318,323,196,327,584,209,86,88,357,360,363,113,241,116,373,247,254 1013,916,1621,175,2488,582,397,395,3160,247,190,1647,209,2955,1730,363,1676,360,1596,584,1387,1200,17,2352,1443,196,1623,1501,291,2288,3117,2185,32,3091,2998,1081,327,1799,798,558,1361,633,276,2378,522,1605,2499,2265,2381,944,241,2779,323,544,318,254,149,2330,425,161,1991,280,724,86,357,174,898,384,301,433,801,2025,116,113,577,385,88,677,373 0.25950170179577764,0.3329162614491058,-0.1081741936250891,1.8185362415383943,-0.6360363435663436,0.7568588077238091,1.0945079100252835,1.1049253152266847,-2.361815391886055,1.5358542924197818,1.7667329517528663,-0.12538587769838372,1.6979807301199143,-1.2051532199617174,-0.177690185818539,1.176476578042439,-0.14270834812699967,1.1865067348823226,-0.09107218097239303,0.7568588077238091,0.02566161901174243,0.1374300649717309,2.850934877568107,-0.5342242617338631,-0.007169221259632773,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,-0.494489054305589,-1.778616500027411,-0.43590826117893794,2.637217657100284,-1.6042899045333228,-1.3068387009445777,0.21440615544338357,1.2650915011001496,-0.213128942203161,0.45984406883424556,0.8048943132507087,0.04192461851956566,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,-0.09107218097239303,-0.6360363435663436,-0.4748273403029004,-0.5543007948494578,0.3184040786732402,1.5693674826960398,-0.9185947277776126,1.284289708677259,0.8402742865808962,1.293823383957412,1.5188836640650665,1.952285648216789,-0.51428752530657,1.0201626829533696,1.8971479790749635,-0.303787854117314,1.4406894094750298,0.5542099181825546,2.2342011612850494,1.1964900873490003,1.825821535867474,0.36168996784734275,1.1358809033740525,1.350128868152097,1.0093338760985888,0.45984406883424556,-0.32228307221127694,2.132957634741071,2.1451816415421097,0.7810014179820873,1.1358809033740525,2.2284083926639537,0.6194206088649225,1.1663992693165688 3193 Sphingolipid metabolic process 17 26 4.186414911603233 2.833951018743619e-05 O95470,Q8NCC3,P06865,P50897,Q16880,Q9P035,Q13510,P17900,Q06136,P16278,P07602,Q9NZJ7,P04062,Q99805,P06280,Q96G23,O15269 Processes and pathways GO Biological process msigdb_gobp 128,193,224,8,140,203,45,79,110,82,20,148,53,343,244,118,252 252,1198,716,128,53,244,224,20,584,82,79,2309,938,8,110,45,140,387,193,118,343,753,556,148,203,1493 1.5188836640650665,0.1374300649717309,0.5542099181825546,2.0894866813375814,2.4355304023078563,1.5526815978228736,1.6185951277994044,2.762496989040066,0.7568588077238091,2.2399742438327923,2.2457277457630314,-0.51428752530657,0.3184040786732402,3.0232917146470886,2.1512615372917634,2.5348046058833917,2.0123785518790727,1.125611440557737,1.7592151429408447,2.1268132851345656,1.2261627415331837,0.5142163574940924,0.8167483885125356,1.9590621281540601,1.7288431475403072,-0.023739075165896593 3193 Ion homeostasis 47 108 4.179478465839673 2.92178383478614e-05 Q96TC7,Q9UM00,P50897,P98194,O75880,O75503,O75027,P09601,P62942,Q7L0J3,Q8NE01,O95295,P30519,Q16611,Q8N511,P20020,P06576,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9BXP2,Q9Y6M7,Q9UJZ1,O95202,Q16891,Q15904,P16615,P51572,P30536,P07686,Q93050,P02786,Q8TAD4,Q9Y487,Q92544,Q8WWC4,P05067,P05023,Q9HD20,Q15043,Q9HC07,Q9Y5X3,O76024,Q05086,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 384,385,8,522,395,139,397,17,276,149,280,409,32,544,161,291,552,425,558,174,175,301,433,189,577,190,318,323,196,327,200,584,208,209,86,88,353,357,360,363,113,241,116,373,247,503,254 1013,916,2346,1621,175,2488,582,397,139,395,3160,247,2307,190,1647,409,209,2955,1730,363,1676,360,1596,552,584,1387,1200,17,2428,2722,2917,2352,1443,196,1623,1501,291,2288,2906,3117,2185,2138,32,200,3091,2998,1081,2187,2039,8,890,327,3161,1799,798,558,1361,633,276,3119,2378,522,1605,503,2499,2265,2381,2412,944,2225,241,2779,323,544,318,254,149,2330,425,2838,161,1991,280,724,86,357,353,208,174,1063,898,384,301,433,801,2025,116,113,735,2478,2151,577,385,88,677,373,2211,189 0.25950170179577764,0.3329162614491058,-0.5342242617338631,-0.1081741936250891,1.8185362415383943,-0.6360363435663436,0.7568588077238091,1.0945079100252835,2.0123785518790727,1.1049253152266847,-2.361815391886055,1.5358542924197818,-0.51428752530657,1.7667329517528663,-0.12538587769838372,1.05233382643295,1.6979807301199143,-1.2051532199617174,-0.177690185818539,1.176476578042439,-0.14270834812699967,1.1865067348823226,-0.09107218097239303,0.8167483885125356,0.7568588077238091,0.02566161901174243,0.1374300649717309,2.850934877568107,-0.5948794930148794,-0.8509667351664257,-1.1309875400384923,-0.5342242617338631,-0.007169221259632773,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,-0.494489054305589,-1.1066521830470757,-1.778616500027411,-0.43590826117893794,-0.39751866108604983,2.637217657100284,1.7364816398521126,-1.6042899045333228,-1.3068387009445777,0.21440615544338357,-0.43590826117893794,-0.3409024311136362,3.0232917146470886,0.36168996784734275,1.2650915011001496,-2.3972018839891502,-0.213128942203161,0.45984406883424556,0.8048943132507087,0.04192461851956566,0.6703324293561015,1.4495286247621895,-1.8085693165877301,-0.5543007948494578,0.8866106862369233,-0.09107218097239303,0.9094287765563077,-0.6360363435663436,-0.4748273403029004,-0.5543007948494578,-0.5745186791895069,0.3184040786732402,-0.4553008972742839,1.5693674826960398,-0.9185947277776126,1.284289708677259,0.8402742865808962,1.293823383957412,1.5188836640650665,1.952285648216789,-0.51428752530657,1.0201626829533696,-0.9877693062177954,1.8971479790749635,-0.303787854117314,1.4406894094750298,0.5542099181825546,2.2342011612850494,1.1964900873490003,1.2064269794639189,1.7057429944746445,1.825821535867474,0.22952714396117282,0.36168996784734275,1.1358809033740525,1.350128868152097,1.0093338760985888,0.45984406883424556,-0.32228307221127694,2.132957634741071,2.1451816415421097,0.5409522516865753,-0.6153848387722859,-0.39751866108604983,0.7810014179820873,1.1358809033740525,2.2284083926639537,0.6194206088649225,1.1663992693165688,-0.43590826117893794,1.7742210599427393 3193 Golgi apparatus 62 166 4.178830791535931 2.930115808497113e-05 P24390,P50897,Q8NE00,P98194,Q9H4A6,O60637,P80303,P09601,P04439,Q9BRK5,A1L0T0,Q9H2V7,Q8WVQ1,Q02818,O95295,O00461,Q9HB40,Q99640,Q8NC54,Q8IYR2,O00231,P49755,Q9NWM8,Q86Y82,O60499,Q9UBU6,Q8NCH0,Q12893,Q5KU26,P55327,Q93050,Q96K12,O43760,P16278,Q16706,O75955,Q8TAD4,O14653,O60476,Q8IZA0,P67812,Q9NTJ5,O15258,Q8TDW0,Q5VW38,Q8IYS2,Q969E2,P05067,O15127,Q92896,Q6ZRP7,Q6NUQ1,Q9UBF8,Q15043,Q14789,Q9HC07,Q9HD45,Q6NUQ4,O15260,Q8IXU6,Q9NW68,Q13190 Localization Protein Atlas Subcellular protein_atlas_subcellular_location_all 2,8,137,522,268,13,14,17,275,151,153,155,283,29,409,34,42,298,44,424,434,304,182,442,63,320,70,456,201,333,208,469,78,82,465,338,86,462,346,93,94,486,355,484,101,230,358,360,106,235,362,483,496,241,369,116,117,243,245,246,380,253 153,844,2616,1013,434,34,2486,462,1331,715,106,355,245,936,1498,2968,2250,78,346,1555,63,13,1961,1706,2105,3029,3116,338,409,1302,2878,275,360,2578,17,2997,669,1258,82,1733,2309,2,1415,2791,2849,3022,2603,1156,2038,1033,1180,694,2682,1053,304,1181,670,8,3096,1800,2111,2638,2962,2659,333,1038,94,14,1746,522,1090,29,2115,605,2116,456,253,1750,2224,3154,369,2641,241,465,1020,201,2227,1579,101,2796,523,483,243,1661,362,2912,2472,1906,2731,442,761,1582,246,2630,424,230,93,1060,1613,1583,44,70,137,86,688,871,2122,484,283,1480,235,1400,208,358,971,469,777,2058,2613,298,2786,3185,151,2805,1242,664,155,2149,3019,268,713,932,2842,2714,2644,42,116,1147,117,2826,1168,486,1169,380,182,2063,496,320,1406,1070,1672,2574,933,2718,1248,1220 1.9318034306318732,0.4042351666901161,-0.7415449896710221,0.25950170179577764,0.9984518432806867,2.605360668935537,-0.6360363435663436,0.9543830980982788,0.05808732403364699,0.5542099181825546,2.163357703140536,1.1964900873490003,1.5442857407745552,0.3184040786732402,-0.04041324981336907,-1.230269771179215,-0.4748273403029004,2.2457277457630314,1.216317751801572,-0.07407874008591195,2.346058243177083,2.977706291199689,-0.303787854117314,-0.16014273539632354,-0.3785188752723304,-1.3852918433246575,-1.778616500027411,1.2359622824697312,1.05233382643295,0.07415070895816572,-1.0585470825916556,1.4495286247621895,1.1865067348823226,-0.6988844633124501,2.850934877568107,-1.3068387009445777,0.6194206088649225,0.1059833465335269,2.2399742438327923,-0.177690185818539,-0.51428752530657,3.21572160468917,0.009297339019232754,-0.9414783391764264,-1.011180888611287,-1.3589269339837995,-0.7201373856155233,0.1684982022009186,-0.3409024311136362,0.2445587153188426,0.15301100508827867,0.5805078633245453,-0.8067138905481915,0.22952714396117282,1.3408498426869389,0.15301100508827867,0.6194206088649225,3.0232917146470886,-1.6327200595968123,-0.213128942203161,-0.3785188752723304,-0.7631090610942425,-1.2051532199617174,-0.7848314137948916,1.2457167051043052,0.2445587153188426,2.1991455126433834,2.919464172904466,-0.177690185818539,0.8866106862369233,0.21440615544338357,2.6595734089805485,-0.3785188752723304,0.7201675789757652,-0.3785188752723304,0.9654822230844401,1.5188836640650665,-0.177690185818539,-0.4553008972742839,-2.292061606724148,1.1663992693165688,-0.7631090610942425,1.5693674826960398,0.9543830980982788,0.25950170179577764,1.7364816398521126,-0.4553008972742839,-0.07407874008591195,2.181344630255124,-0.9414783391764264,0.8866106862369233,0.9320183829658302,1.5610421002753638,-0.12538587769838372,1.1865067348823226,-1.1066521830470757,-0.6153848387722859,-0.2671646500903092,-0.8509667351664257,0.9875161701203701,0.5007368375870117,-0.07407874008591195,1.5442857407745552,-0.7415449896710221,1.0201626829533696,1.6104756568747511,2.205038320950641,0.22952714396117282,-0.09107218097239303,-0.07407874008591195,2.5396088192635413,2.302208489423922,2.0319712644098264,2.2342011612850494,0.5935493889180543,0.39013449402256833,-0.3785188752723304,0.9320183829658302,1.4318115854602973,-0.023739075165896593,1.5941352237229818,0.02566161901174243,1.7057429944746445,1.1964900873490003,0.30380731745916084,0.9543830980982788,0.48718206135466036,-0.3409024311136362,-0.7201373856155233,1.38683389940539,-0.9185947277776126,-4.006248442209549,1.945483805688231,-0.9414783391764264,0.12175448251162654,0.6322515068949177,1.9249245939305628,-0.39751866108604983,-1.3327768033414031,1.4670922847773513,0.5673949130081869,0.3329162614491058,-0.9877693062177954,-0.8287583635800084,-0.7631090610942425,2.563411491546392,2.132957634741071,0.1838925440088085,2.132957634741071,-0.9645358333127365,0.1684982022009186,0.9320183829658302,0.1684982022009186,1.1461017884280336,1.7965090219596693,-0.3409024311136362,0.9207519138862322,1.293823383957412,0.02566161901174243,0.22952714396117282,-0.12538587769838372,-0.6777844648834328,0.3329162614491058,-0.8287583635800084,0.12175448251162654,0.1374300649717309 3193 Protein localization to mitochondrion 27 59 4.176431611630534 2.961177143645521e-05 Q9P0J0,Q5JRX3,Q53H12,O60830,O95831,Q9NS69,P55786,Q8N4H5,Q9Y6C9,Q99595,Q9Y512,O14737,Q9GZY8,O00165,P52789,Q15070,P49257,P51572,P30536,O14925,Q9Y5J9,Q9Y371,Q8WWC4,Q99797,Q15388,Q10713,O43615 Processes and pathways GO Biological process msigdb_gobp 129,512,387,5,389,10,396,15,143,19,290,294,299,303,435,65,447,327,200,92,488,487,357,359,232,236,376 303,1279,1013,1249,294,92,716,376,5,2072,1152,769,2636,718,2829,389,525,1413,2458,1255,2252,2287,2373,200,2464,2832,447,2467,327,435,396,2963,236,65,232,2168,639,387,512,968,15,928,357,1909,19,359,299,1327,10,129,1884,3005,730,862,487,290,488,602,143 1.3408498426869389,0.09011573382996567,0.25950170179577764,0.1059833465335269,1.38683389940539,2.2109109040904884,0.5542099181825546,1.1461017884280336,3.1165747016179965,-0.3596472519831671,0.1684982022009186,0.48718206135466036,-0.7631090610942425,0.5542099181825546,-0.9877693062177954,1.1152930343193794,0.8751148153965543,0.009297339019232754,-0.6153848387722859,0.1059833465335269,-0.4748273403029004,-0.494489054305589,-0.5543007948494578,1.7364816398521126,-0.6153848387722859,-0.9877693062177954,0.9765264378161742,-0.6153848387722859,1.2650915011001496,0.9984518432806867,1.1049253152266847,-1.2051532199617174,1.5859138151123813,2.3406400045953175,1.6023224295792171,-0.41664798954862137,0.6577068359941382,1.125611440557737,0.8980485194817284,0.30380731745916084,2.9120109684113684,0.3329162614491058,1.1964900873490003,-0.2671646500903092,2.8113998714497686,1.1964900873490003,1.38683389940539,0.07415070895816572,3.0024397548003465,2.0831876730587275,-0.24903411518852805,-1.3068387009445777,0.5542099181825546,0.4042351666901161,0.9320183829658302,1.4049437781239236,0.9320183829658302,0.7324623353077244,1.992569263975948 3193 Transport of small molecules 63 147 4.169599245134288 3.051357196093285e-05 P40855,P12235,Q99623,Q9Y277,P98194,Q9C0H2,Q8WTV0,O75027,P38571,P09601,Q9BUN8,P28070,P53985,P05141,P35610,P30519,P08195,P20020,P28072,P49721,P55011,P45880,P08183,Q9BPX6,P21796,P12236,Q8IYU8,O00231,Q15758,Q9UBX3,Q9Y6M7,Q9UJZ1,O95202,P35613,Q15904,P16615,Q9UBV2,Q70HW3,P20618,Q93050,Q9H936,P02786,Q8TAD4,Q9Y487,Q8TB61,P10644,Q9NW15,Q96TA2,P28288,Q9BU23,Q8WWC4,Q8TDW0,Q99797,P11166,Q10713,P05023,P25787,Q9HD20,Q15043,P61916,Q99808,P27105,P51798 Processes and pathways Reactome Pathways msigdb_reactome 386,259,388,135,522,11,141,397,526,17,147,405,407,284,410,32,417,291,300,46,558,48,176,301,51,179,425,434,565,57,189,577,190,192,323,196,198,77,332,208,593,209,86,88,89,604,220,348,473,485,357,484,359,612,236,363,368,113,241,491,372,115,383 434,3009,2996,2156,2810,2033,1251,397,2072,2306,3160,1015,2702,190,749,209,363,1676,284,2427,684,176,417,1677,17,604,612,259,179,2107,196,1967,291,1794,332,693,2547,2288,51,2928,368,3106,3156,115,2743,405,300,797,473,32,3091,1971,833,786,410,807,192,3092,2038,962,526,2998,386,2980,48,1737,2110,46,1182,3161,383,1054,407,798,558,2867,2584,2375,1309,624,1361,491,1569,1899,2885,2407,2587,942,522,2043,2589,853,236,1452,2221,1453,1425,2381,2017,1343,1575,241,565,323,1987,1209,77,2731,425,1455,724,86,89,484,141,357,1239,208,1511,348,1165,2569,388,359,372,301,485,147,11,859,705,593,113,2448,220,198,57,780,2151,577,1378,2596,1218,135,88,677,189 0.9984518432806867,-1.3327768033414031,-1.3068387009445777,-0.41664798954862137,-0.9645358333127365,-0.3409024311136362,0.1059833465335269,1.0945079100252835,-0.3596472519831671,-0.51428752530657,-2.361815391886055,0.25950170179577764,-0.8287583635800084,1.7667329517528663,0.5142163574940924,1.6979807301199143,1.176476578042439,-0.14270834812699967,1.4228948856937176,-0.5948794930148794,0.5935493889180543,1.8112225085127378,1.0416622545332883,-0.14270834812699967,2.850934877568107,0.7201675789757652,0.7078077588474234,1.5017677751833673,1.803880161059405,-0.3785188752723304,1.751667447018552,-0.303787854117314,1.3959088234962316,-0.213128942203161,1.2457167051043052,0.5805078633245453,-0.6777844648834328,-0.494489054305589,2.5007588066882245,-1.1555145615983378,1.1663992693165688,-1.690319243336421,-2.326770357792346,2.132957634741071,-0.8733409382481655,1.0629537868319574,1.350128868152097,0.45984406883424556,0.9432286304255554,2.637217657100284,-1.6042899045333228,-0.303787854117314,0.4182557487269513,0.4735513630461408,1.05233382643295,0.44605949669078204,1.7592151429408447,-1.6042899045333228,-0.3409024311136362,0.30380731745916084,0.8751148153965543,-1.3068387009445777,1.125611440557737,-1.2555878176142559,2.515439795372476,-0.177690185818539,-0.3785188752723304,2.520303335299205,0.15301100508827867,-2.3972018839891502,1.1358809033740525,0.22952714396117282,1.0629537868319574,0.45984406883424556,0.8048943132507087,-1.0347727466327314,-0.6988844633124501,-0.5543007948494578,0.07415070895816572,0.682890738977402,0.04192461851956566,0.9207519138862322,-0.07407874008591195,-0.2671646500903092,-1.0585470825916556,-0.5745186791895069,-0.6988844633124501,0.3184040786732402,0.8866106862369233,-0.3409024311136362,-0.6988844633124501,0.4042351666901161,1.5859138151123813,-0.007169221259632773,-0.4553008972742839,-0.007169221259632773,0.009297339019232754,-0.5543007948494578,-0.32228307221127694,0.05808732403364699,-0.07407874008591195,1.5693674826960398,0.7929788244184839,1.284289708677259,-0.303787854117314,0.1374300649717309,2.2514617717609795,-0.8509667351664257,1.0201626829533696,-0.007169221259632773,0.5542099181825546,2.2342011612850494,2.2225958317358057,0.9320183829658302,1.9991966569128934,1.1964900873490003,0.12175448251162654,1.7057429944746445,-0.04041324981336907,1.216317751801572,0.1684982022009186,-0.6777844648834328,1.125611440557737,1.1964900873490003,1.1663992693165688,1.350128868152097,0.9320183829658302,1.9658133945446885,2.984818292512709,0.4042351666901161,0.5805078633245453,0.7446925671515504,2.1451816415421097,-0.5948794930148794,1.6427531946624607,1.751667447018552,2.39928112695771,0.48718206135466036,-0.39751866108604983,0.7810014179820873,0.04192461851956566,-0.6988844633124501,0.1374300649717309,2.051351117777622,2.2284083926639537,0.6194206088649225,1.7742210599427393 3193 Organic anion transmembrane transporter activity 24 29 4.165901284447439 3.1012488537207616e-05 P12235,Q9H2D1,Q9Y619,P53985,P05141,Q14728,P08195,Q96NB2,Q6NUK1,Q9UJS0,P12236,P53007,Q15758,Q9UBX3,Q9Y6M7,Q9HC21,O43808,Q9BQT8,Q9H936,Q9H9B4,Q8TB61,O75746,P11166,Q99808 Functions GO Molecular function msigdb_gomf 259,7,267,407,284,411,417,546,419,169,179,440,565,57,189,319,444,197,593,601,89,350,612,372 2346,444,350,284,417,612,259,179,833,866,440,407,644,411,565,419,1209,89,546,372,197,7,593,601,319,57,169,267,189 -0.5342242617338631,0.9765264378161742,1.2064269794639189,1.4228948856937176,1.0416622545332883,0.7078077588474234,1.5017677751833673,1.803880161059405,0.4182557487269513,0.39013449402256833,0.9875161701203701,1.0629537868319574,0.6450133877649504,1.05233382643295,0.7929788244184839,1.0416622545332883,0.1374300649717309,2.2225958317358057,0.8402742865808962,1.1663992693165688,1.751667447018552,3.043830354362099,0.7446925671515504,0.7324623353077244,1.293823383957412,2.39928112695771,1.854681789652418,1.4758172511688186,1.7742210599427393 3193 Intrinsic component of mitochondrial inner membrane 23 30 4.160193927092086 3.179774847428263e-05 Q53H12,Q9Y2R0,Q5XKP0,O60830,O75880,Q99595,Q9NVH1,Q9Y512,Q96NB2,Q13505,Q6P4A7,Q00325,O43819,Q16891,Q9HC21,Q15070,Q9NX63,O75431,P17152,Q9BUR5,O14925,Q6UXV4,Q9H3K2 Localization GO Cellular component msigdb_gocc 387,4,260,5,395,19,408,290,546,36,166,554,175,318,319,65,461,583,592,213,92,352,234 92,175,5,583,395,592,2465,2374,554,36,65,821,318,387,260,166,352,724,546,19,213,234,601,1512,319,408,461,4,677,290 2.2109109040904884,1.8185362415383943,3.1165747016179965,0.7568588077238091,1.1049253152266847,0.7446925671515504,-0.6153848387722859,-0.5543007948494578,0.8167483885125356,2.596136262438205,2.3406400045953175,0.4321969562595515,1.293823383957412,1.125611440557737,1.5017677751833673,1.8760367688861144,1.2064269794639189,0.5542099181825546,0.8402742865808962,2.8113998714497686,1.682361685022864,1.6023224295792171,0.7324623353077244,-0.04041324981336907,1.293823383957412,1.0629537868319574,0.9654822230844401,3.129385678191442,0.6194206088649225,1.4049437781239236 3193 Receptor 13 34 4.14248993671283 3.43555447575028e-05 P35613,P24390,Q5KU26,Q14108,Q9NS69,Q9Y5M8,Q8WTV0,P11279,P02786,Q99720,Q14739,O15173,O43731 Functions Protein Atlas Molecular function protein_atlas_molecular_function 192,2,201,9,10,108,141,206,209,50,210,56,26 258,1785,2033,56,26,209,1078,785,2005,1560,2007,1964,206,669,2008,1155,2,192,536,1058,9,210,674,565,201,141,1062,1400,388,50,10,1073,108,2300 1.5017677751833673,-0.213128942203161,-0.3409024311136362,2.39928112695771,2.6816050945494077,1.6979807301199143,0.21440615544338357,0.4735513630461408,-0.32228307221127694,-0.07407874008591195,-0.32228307221127694,-0.303787854117314,1.7057429944746445,0.6194206088649225,-0.32228307221127694,0.1684982022009186,3.21572160468917,1.7592151429408447,0.8519470898097677,0.22952714396117282,3.0232917146470886,1.6979807301199143,0.6194206088649225,0.7929788244184839,1.7364816398521126,1.9991966569128934,0.22952714396117282,0.02566161901174243,1.125611440557737,2.5056676046326203,3.0024397548003465,0.22952714396117282,2.163357703140536,-0.494489054305589 3193 Protein localization 40 73 4.112326450286512 3.916919009361308e-05 Q5JRX3,P40855,P12235,P50402,O60830,O75381,Q8NBU5,Q9NS69,Q8N4H5,P09601,O96008,Q99595,Q9Y512,P08574,Q13505,Q15067,Q9UJS0,P06576,O43681,Q9NR77,P21796,P12236,O43808,P51648,Q9NX63,O75431,Q9Y5L4,O14925,O15228,O75746,P28288,P46379,Q9Y5J9,Q9BY49,P05067,Q15388,Q10713,O43615,Q13190,Q3ZCQ8 Processes and pathways Reactome Pathways msigdb_reactome 512,386,259,261,5,263,647,10,15,17,525,19,290,668,36,420,169,552,557,49,51,179,444,71,461,583,602,92,471,350,473,351,488,231,360,232,236,376,253,639 667,884,766,92,471,376,557,919,444,5,263,2896,583,2072,2739,350,2862,1152,525,360,552,668,3146,17,2458,259,179,2008,51,1931,1333,473,2705,3031,2465,386,351,261,1360,71,850,2375,2899,2436,236,751,253,36,420,232,639,512,2913,15,928,647,2334,19,2614,231,1327,49,10,461,1493,2341,169,2699,862,1999,290,488,602 0.6194206088649225,0.36168996784734275,0.48718206135466036,2.2109109040904884,0.9432286304255554,1.1461017884280336,0.8048943132507087,0.3329162614491058,0.9765264378161742,3.1165747016179965,1.4845046522176364,-1.082506135737104,0.7568588077238091,-0.3596472519831671,-0.8733409382481655,1.2064269794639189,-1.0347727466327314,0.1684982022009186,0.8751148153965543,1.1865067348823226,0.8167483885125356,0.6194206088649225,-2.1564896067692816,2.850934877568107,-0.6153848387722859,1.5017677751833673,1.803880161059405,-0.32228307221127694,2.5007588066882245,-0.28541547461577405,0.05808732403364699,0.9432286304255554,-0.8287583635800084,-1.3852918433246575,-0.6153848387722859,1.125611440557737,1.2064269794639189,1.4931547427369818,0.04192461851956566,2.2966451596705606,0.4042351666901161,-0.5543007948494578,-1.082506135737104,-0.5948794930148794,1.5859138151123813,0.5142163574940924,1.5188836640650665,2.596136262438205,1.03093867386121,1.6023224295792171,0.6577068359941382,0.8980485194817284,-1.1066521830470757,2.9120109684113684,0.3329162614491058,0.6450133877649504,-0.51428752530657,2.8113998714497686,-0.7201373856155233,1.6104756568747511,0.07415070895816572,2.515439795372476,3.0024397548003465,0.9654822230844401,-0.023739075165896593,-0.51428752530657,1.854681789652418,-0.8067138905481915,0.4042351666901161,-0.303787854117314,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 Azurophil granule 31 68 4.101782327646615 4.099798670997856e-05 Q9BTY2,Q9H7Z7,P42785,Q6IAA8,Q92820,P10253,P53634,P07602,Q9NZJ7,O00584,Q13217,O43681,Q96CS3,Q8NF37,P13473,Q07065,P07686,P17900,P11279,P16278,Q92542,O15400,O95721,P10619,P15586,P06865,P61916,P06280,P27105,O15260,Q9NQX7 Localization GO Cellular component msigdb_gocc 257,393,136,523,529,145,402,20,148,285,549,557,560,181,72,73,584,79,206,82,211,345,472,98,225,224,491,244,115,245,127 2301,285,765,245,345,557,623,2002,2348,472,888,591,244,224,1522,2368,20,584,145,98,1895,206,72,1258,225,82,79,2880,115,2138,3030,1448,136,2624,2920,1528,1530,1085,2684,402,1086,2584,2316,491,2042,1745,2639,73,549,1751,523,2148,181,211,529,560,2569,1295,883,1025,257,859,393,127,2984,148,1493,2635 -0.51428752530657,1.413939040620315,0.48718206135466036,1.5442857407745552,1.216317751801572,0.8048943132507087,0.682890738977402,-0.32228307221127694,-0.5342242617338631,0.9432286304255554,0.36168996784734275,0.7446925671515504,1.5526815978228736,1.6185951277994044,-0.05719278632694883,-0.5543007948494578,2.762496989040066,0.7568588077238091,1.9658133945446885,2.1872987787678158,-0.2671646500903092,1.7057429944746445,2.291063262623579,0.1059833465335269,1.6185951277994044,2.2399742438327923,2.2457277457630314,-1.0585470825916556,2.132957634741071,-0.39751866108604983,-1.3852918433246575,-0.007169221259632773,2.0384546855538916,-0.7415449896710221,-1.1309875400384923,-0.05719278632694883,-0.05719278632694883,0.21440615544338357,-0.8067138905481915,1.0735225288658525,0.21440615544338357,-0.6988844633124501,-0.51428752530657,0.9207519138862322,-0.3409024311136362,-0.177690185818539,-0.7631090610942425,2.28546270022205,0.8285415486462114,-0.177690185818539,0.8866106862369233,-0.39751866108604983,1.7965090219596693,1.682361685022864,0.8751148153965543,0.8048943132507087,-0.6777844648834328,0.09011573382996567,0.3759530057373177,0.25950170179577764,1.510343999684222,0.4042351666901161,1.1152930343193794,2.095763221365341,-1.2555878176142559,1.9590621281540601,-0.023739075165896593,-0.7415449896710221 3193 Endoplasmic reticulum golgi intermediate compartment 24 47 4.072332513155766 4.654466791520484e-05 P24390,P61019,P80303,P53634,Q03518,Q9BVK6,Q96GC9,Q02818,Q8N511,Q9UBR2,P49755,Q15363,Q12907,P49257,Q15904,P51572,O14653,Q9Y3B3,O15258,Q9Y3A6,Q14789,O15260,Q9Y282,Q13190 Localization GO Cellular component msigdb_gocc 2,520,14,402,152,415,156,29,161,293,304,61,574,447,323,327,462,95,355,498,369,245,119,253 462,355,245,782,903,684,1200,1966,2,2185,447,304,1159,327,2962,402,1086,520,14,29,152,574,253,369,1937,61,323,599,823,161,1480,1663,992,156,858,415,2276,664,997,2101,293,2478,119,498,95,1220,1854 0.9543830980982788,1.1964900873490003,1.5442857407745552,0.4735513630461408,0.34734463722339803,0.5935493889180543,0.1374300649717309,-0.303787854117314,3.21572160468917,-0.43590826117893794,0.9765264378161742,1.3408498426869389,0.1684982022009186,1.2650915011001496,-1.2051532199617174,1.0735225288658525,0.21440615544338357,0.8866106862369233,2.919464172904466,2.6595734089805485,1.9386564503168657,0.7810014179820873,1.5188836640650665,1.1663992693165688,-0.28541547461577405,2.3514587661376916,1.284289708677259,0.7324623353077244,0.4321969562595515,1.8971479790749635,-0.023739075165896593,-0.12538587769838372,0.2891251966313216,1.9180197862656285,0.4042351666901161,1.05233382643295,-0.4748273403029004,0.6322515068949177,0.2891251966313216,-0.3596472519831671,1.3959088234962316,-0.6153848387722859,2.1268132851345656,0.9207519138862322,2.1991455126433834,0.1374300649717309,-0.23102262249362931 3193 Vacuole organization 28 54 4.069920616471857 4.702915979470923e-05 Q15286,P50897,Q14108,Q6IAA8,O75503,Q9H0U4,P10253,Q7Z3C6,O14773,Q96GC9,O95295,Q8N511,P50851,Q8TBX8,P04062,Q86Y82,P16615,Q9UHD9,P07686,Q16706,P11117,Q8WVM8,Q9Y371,Q15042,P62820,Q9HC07,P42345,P54802 Processes and pathways GO Biological process msigdb_gobp 771,8,9,523,139,664,145,660,150,156,409,161,670,689,53,442,196,325,584,465,85,734,487,752,758,116,500,126 1013,150,903,139,769,409,2829,53,1522,584,145,85,196,1679,500,670,8,890,2111,126,2376,1055,758,964,9,868,752,771,465,523,660,442,161,689,734,1063,156,2594,949,664,1351,930,116,1954,1148,1298,325,1958,1850,1959,1171,2030,487,1195 0.25950170179577764,1.945483805688231,0.34734463722339803,2.0123785518790727,0.48718206135466036,1.05233382643295,-0.9877693062177954,2.4355304023078563,-0.05719278632694883,0.7568588077238091,1.9658133945446885,2.2342011612850494,1.751667447018552,-0.14270834812699967,0.9094287765563077,0.6194206088649225,3.0232917146470886,0.36168996784734275,-0.3785188752723304,2.095763221365341,-0.5543007948494578,0.22952714396117282,0.5007368375870117,0.30380731745916084,3.0232917146470886,0.39013449402256833,0.5142163574940924,0.48718206135466036,0.9543830980982788,0.8866106862369233,0.6322515068949177,0.9875161701203701,1.8971479790749635,0.5935493889180543,0.5409522516865753,0.22952714396117282,1.9180197862656285,-0.6988844633124501,0.3184040786732402,0.6322515068949177,0.05808732403364699,0.3329162614491058,2.132957634741071,-0.28541547461577405,0.1838925440088085,0.09011573382996567,1.284289708677259,-0.28541547461577405,-0.23102262249362931,-0.28541547461577405,0.1684982022009186,-0.32228307221127694,0.9320183829658302,0.15301100508827867 3193 Organic acid transmembrane transport 23 29 4.027031327501303 5.648550904790994e-05 Q9H2D1,Q02978,Q9Y619,P53985,P08195,Q96NB2,P23786,Q9UJS0,O75915,P08183,P31751,P53007,Q15758,Q9UBX3,O43772,Q9BQT8,Q9H936,Q9H9B4,O75746,P28288,Q8TDW0,P11166,O60831 Processes and pathways GO Biological process msigdb_gobp 7,644,267,407,417,546,167,169,551,176,564,440,565,57,191,197,593,601,350,473,484,612,489 191,489,350,551,1078,176,417,612,167,473,564,1202,833,866,923,440,407,644,565,484,546,197,7,705,593,601,57,169,267 1.7592151429408447,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.21440615544338357,1.8112225085127378,1.0416622545332883,0.7078077588474234,1.8618274754931423,0.9432286304255554,0.7929788244184839,0.1374300649717309,0.4182557487269513,0.39013449402256833,0.3329162614491058,0.9875161701203701,1.0629537868319574,0.6450133877649504,0.7929788244184839,0.9320183829658302,0.8402742865808962,1.751667447018552,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.39928112695771,1.854681789652418,1.4758172511688186 3193 Mitochondrial membrane organization 28 47 4.017082101597094 5.892319976563698e-05 Q9P0J0,P12235,Q5XKP0,Q53H12,Q9NS69,Q9NVH1,P05141,Q16611,Q9Y512,Q13505,O14737,P45880,P52789,Q16891,O95202,Q15070,Q9NX63,O75431,P17152,Q9Y5L4,Q9BUR5,Q8IWA4,O60313,Q6UXV4,Q9Y5J9,Q8WWC4,Q9H3K2,Q3ZCQ8 Processes and pathways GO Biological process msigdb_gobp 129,259,260,387,10,408,284,544,290,36,294,48,435,318,190,65,461,583,592,602,213,218,221,352,488,357,234,639 1013,294,221,583,1152,769,190,1356,284,1413,1622,259,592,2678,2373,2832,2465,2706,48,2187,2467,435,36,65,544,318,639,387,260,352,218,969,1137,357,881,213,234,10,408,461,129,730,862,677,290,488,602 0.25950170179577764,1.38683389940539,1.6266810625618235,0.7568588077238091,0.1684982022009186,0.48718206135466036,1.7667329517528663,0.04192461851956566,1.4228948856937176,0.009297339019232754,-0.1081741936250891,1.5017677751833673,0.7446925671515504,-0.8067138905481915,-0.5543007948494578,-0.9877693062177954,-0.6153848387722859,-0.8287583635800084,2.515439795372476,-0.43590826117893794,-0.6153848387722859,0.9984518432806867,2.596136262438205,2.3406400045953175,0.8402742865808962,1.293823383957412,0.6577068359941382,1.125611440557737,1.5017677751833673,1.2064269794639189,1.6586937760640963,0.30380731745916084,0.1838925440088085,1.1964900873490003,0.3759530057373177,1.682361685022864,1.6023224295792171,3.0024397548003465,1.0629537868319574,0.9654822230844401,2.0831876730587275,0.5542099181825546,0.4042351666901161,0.6194206088649225,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 Cellular ion homeostasis 41 87 4.005980381267128 6.176077546227177e-05 Q96TC7,Q9UM00,P50897,P98194,O75880,O75503,O75027,P09601,P62942,Q7L0J3,O95295,Q16611,Q8N511,P20020,P06576,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9Y6M7,O95202,Q9UJZ1,Q16891,Q15904,P16615,P51572,P07686,Q93050,P02786,Q8TAD4,Q9Y487,Q92544,Q8WWC4,P05067,P05023,Q9HD20,Q15043,Q9HC07,O76024,Q05086 Processes and pathways GO Biological process msigdb_gobp 384,385,8,522,395,139,397,17,276,149,409,544,161,291,552,425,558,174,175,301,189,190,577,318,323,196,327,584,208,209,86,88,353,357,360,363,113,241,116,247,503 1013,916,2346,175,2488,582,397,139,395,3160,247,190,1647,409,209,363,1676,360,1596,552,584,1387,1200,17,2722,2917,2352,1443,196,1623,1501,291,2288,2906,3117,2185,2138,3091,2998,1081,8,890,327,3161,1799,798,558,1361,633,276,2378,522,1605,503,2381,944,241,2779,323,544,318,149,2330,425,161,724,86,357,353,208,174,1063,898,384,301,801,2025,116,113,2478,2151,577,385,88,677,2211,189 0.25950170179577764,0.3329162614491058,-0.5342242617338631,1.8185362415383943,-0.6360363435663436,0.7568588077238091,1.0945079100252835,2.0123785518790727,1.1049253152266847,-2.361815391886055,1.5358542924197818,1.7667329517528663,-0.12538587769838372,1.05233382643295,1.6979807301199143,1.176476578042439,-0.14270834812699967,1.1865067348823226,-0.09107218097239303,0.8167483885125356,0.7568588077238091,0.02566161901174243,0.1374300649717309,2.850934877568107,-0.8509667351664257,-1.1309875400384923,-0.5342242617338631,-0.007169221259632773,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,-0.494489054305589,-1.1066521830470757,-1.778616500027411,-0.43590826117893794,-0.39751866108604983,-1.6042899045333228,-1.3068387009445777,0.21440615544338357,3.0232917146470886,0.36168996784734275,1.2650915011001496,-2.3972018839891502,-0.213128942203161,0.45984406883424556,0.8048943132507087,0.04192461851956566,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,-0.09107218097239303,0.9094287765563077,-0.5543007948494578,0.3184040786732402,1.5693674826960398,-0.9185947277776126,1.284289708677259,0.8402742865808962,1.293823383957412,1.952285648216789,-0.51428752530657,1.0201626829533696,1.8971479790749635,0.5542099181825546,2.2342011612850494,1.1964900873490003,1.2064269794639189,1.7057429944746445,1.825821535867474,0.22952714396117282,0.36168996784734275,1.1358809033740525,1.350128868152097,0.45984406883424556,-0.32228307221127694,2.132957634741071,2.1451816415421097,-0.6153848387722859,-0.39751866108604983,0.7810014179820873,1.1358809033740525,2.2284083926639537,0.6194206088649225,-0.43590826117893794,1.7742210599427393 3193 Endoplasmic reticulum protein containing complex 28 60 3.9905325073112974 6.592511220748776e-05 P51571,P61803,Q96S52,Q9BUN8,P04439,P62942,Q03518,Q53GQ0,Q5J8M3,O43681,Q96CS3,Q9UGP8,Q9UBU6,Q15005,Q9UBV2,P46977,Q8TCT9,Q92643,Q8TCJ2,P13674,P67812,Q6NUQ1,Q9H490,Q9Y5M8,Q9NPA0,P04843,P49458,O15269 Localization GO Cellular component msigdb_gocc 519,658,663,147,275,276,152,286,550,557,560,571,320,322,198,204,80,468,467,464,94,483,366,108,239,490,374,252 844,252,1198,2542,557,2036,275,490,815,684,464,1256,1443,2620,2185,2037,1448,204,374,519,2584,2899,1655,941,658,276,94,152,1607,880,1429,322,893,1937,286,550,483,1163,909,2273,467,80,468,2611,1401,560,663,147,859,366,239,1170,2392,320,198,571,2479,1102,108,1439 0.4042351666901161,1.5188836640650665,0.1374300649717309,-0.6777844648834328,0.8048943132507087,-0.3409024311136362,1.4495286247621895,0.9207519138862322,0.4321969562595515,0.5935493889180543,0.9543830980982788,0.1059833465335269,-0.007169221259632773,-0.7415449896710221,-0.43590826117893794,-0.3409024311136362,-0.007169221259632773,1.7211740059471201,1.1562744576555442,0.8866106862369233,-0.6988844633124501,-1.082506135737104,-0.12538587769838372,0.3184040786732402,0.6322515068949177,1.4495286247621895,2.1991455126433834,1.9386564503168657,-0.09107218097239303,0.3759530057373177,0.009297339019232754,1.284289708677259,0.36168996784734275,-0.28541547461577405,1.413939040620315,0.8285415486462114,0.9320183829658302,0.1684982022009186,0.34734463722339803,-0.4748273403029004,0.9543830980982788,2.2457277457630314,0.9543830980982788,-0.7201373856155233,0.02566161901174243,0.8048943132507087,0.6322515068949177,1.9658133945446885,0.4042351666901161,1.176476578042439,1.5776579775269348,0.1684982022009186,-0.5543007948494578,1.293823383957412,1.751667447018552,0.7929788244184839,-0.6153848387722859,0.21440615544338357,2.163357703140536,0.009297339019232754 3193 Endoplasmic reticulum lumen 26 57 3.962785261982504 7.40804096455161e-05 Q9BTY2,P53634,Q02818,O00584,Q9NZ08,Q32P28,Q9UBR2,Q13217,Q9Y680,O43681,P07237,Q9NWM8,P27824,Q14257,O43852,Q07065,Q96AY3,Q9BTV4,P13674,O75718,Q86UP2,Q8TED1,Q5JRA6,P05067,Q9BV10,O76024 Localization GO Cellular component msigdb_gocc 257,402,29,285,159,545,293,549,40,557,684,182,311,186,315,73,328,460,464,717,733,610,613,360,111,247 285,1123,557,315,1705,717,247,360,684,2997,1651,1597,464,1256,1443,1258,1177,2620,2906,2185,311,2138,1474,2037,1159,402,29,73,549,186,1429,1937,759,545,613,1136,733,1163,1270,1432,2148,610,992,328,898,858,460,257,111,182,997,159,293,2392,1618,1102,40 1.413939040620315,0.1838925440088085,0.8048943132507087,1.3033138565109923,-0.16014273539632354,0.5542099181825546,1.5358542924197818,1.1865067348823226,0.5935493889180543,-1.3068387009445777,-0.12538587769838372,-0.09107218097239303,0.9543830980982788,0.1059833465335269,-0.007169221259632773,0.1059833465335269,0.15301100508827867,-0.7415449896710221,-1.1066521830470757,-0.43590826117893794,1.3221664240422288,-0.39751866108604983,-0.023739075165896593,-0.3409024311136362,0.1684982022009186,1.0735225288658525,2.6595734089805485,2.28546270022205,0.8285415486462114,1.7816796524116962,0.009297339019232754,-0.28541547461577405,0.5007368375870117,0.8402742865808962,0.7078077588474234,0.1838925440088085,0.5409522516865753,0.1684982022009186,0.1059833465335269,0.009297339019232754,-0.39751866108604983,0.7201675789757652,0.2891251966313216,1.2650915011001496,0.36168996784734275,0.4042351666901161,0.9654822230844401,1.510343999684222,2.1512615372917634,1.7965090219596693,0.2891251966313216,1.9041316359550924,1.3959088234962316,-0.5543007948494578,-0.09107218097239303,0.21440615544338357,2.572831939044648 3193 Mitochondrial protein import 23 35 3.953345444809353 7.706605022139712e-05 Q5JRX3,P12235,O60830,Q9NS69,Q8N4H5,O96008,Q99595,Q9Y512,Q13505,Q9UJS0,P06576,P21796,P12236,Q9NX63,O75431,Q9Y5L4,O14925,O75746,Q9Y5J9,Q15388,Q10713,O43615,Q3ZCQ8 Processes and pathways Reactome Pathways msigdb_reactome 512,259,5,10,15,525,19,290,36,169,552,51,179,461,583,602,92,350,488,232,236,376,639 92,376,5,2896,583,2072,350,1152,525,552,668,2458,259,179,51,1333,2465,1360,236,36,232,639,512,15,928,19,2614,1327,10,461,169,862,290,488,602 2.2109109040904884,1.1461017884280336,3.1165747016179965,-1.082506135737104,0.7568588077238091,-0.3596472519831671,1.2064269794639189,0.1684982022009186,0.8751148153965543,0.8167483885125356,0.6194206088649225,-0.6153848387722859,1.5017677751833673,1.803880161059405,2.5007588066882245,0.05808732403364699,-0.6153848387722859,0.04192461851956566,1.5859138151123813,2.596136262438205,1.6023224295792171,0.6577068359941382,0.8980485194817284,2.9120109684113684,0.3329162614491058,2.8113998714497686,-0.7201373856155233,0.07415070895816572,3.0024397548003465,0.9654822230844401,1.854681789652418,0.4042351666901161,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 SLC25 family of mitochondrial transporters 20 21 3.951974741414131 7.75089234128501e-05 P12235,Q9H2D1,Q9Y619,Q9Y6C9,Q9NZJ7,P05141,Q9BSK2,Q6NUK1,Q00325,Q9UJS0,P12236,P53007,Q9UBX3,O43772,Q9HC21,O43808,Q9BQT8,Q70HW3,Q9H936,O75746 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 259,7,267,143,148,284,162,419,554,169,179,440,57,191,319,444,197,77,593,350 191,444,350,284,259,179,440,554,644,419,77,197,162,7,593,319,148,57,169,267,143 1.7592151429408447,0.9765264378161742,1.2064269794639189,1.4228948856937176,1.5017677751833673,1.803880161059405,0.9875161701203701,0.8167483885125356,0.6450133877649504,1.0416622545332883,2.2514617717609795,1.751667447018552,1.8971479790749635,3.043830354362099,0.7446925671515504,1.293823383957412,1.9590621281540601,2.39928112695771,1.854681789652418,1.4758172511688186,1.992569263975948 3193 Mitochondrial substrate/solute carrier [IPR018108] 20 21 3.951974741414131 7.75089234128501e-05 P12235,Q9H2D1,Q9Y619,Q9Y6C9,Q9NZJ7,P05141,Q9BSK2,Q6NUK1,Q00325,Q9UJS0,P12236,P53007,Q9UBX3,O43772,Q9HC21,O43808,Q9BQT8,Q70HW3,Q9H936,O75746 Sequence InterPro Repeat interpro_repeat 259,7,267,143,148,284,162,419,554,169,179,440,57,191,319,444,197,77,593,350 191,444,350,284,259,179,440,554,644,419,77,197,162,7,593,319,148,57,169,267,143 1.7592151429408447,0.9765264378161742,1.2064269794639189,1.4228948856937176,1.5017677751833673,1.803880161059405,0.9875161701203701,0.8167483885125356,0.6450133877649504,1.0416622545332883,2.2514617717609795,1.751667447018552,1.8971479790749635,3.043830354362099,0.7446925671515504,1.293823383957412,1.9590621281540601,2.39928112695771,1.854681789652418,1.4758172511688186,1.992569263975948 3193 Mitochondrial carrier domain superfamily [IPR023395] 20 21 3.951974741414131 7.75089234128501e-05 P12235,Q9H2D1,Q9Y619,Q9Y6C9,Q9NZJ7,P05141,Q9BSK2,Q6NUK1,Q00325,Q9UJS0,P12236,P53007,Q9UBX3,O43772,Q9HC21,O43808,Q9BQT8,Q70HW3,Q9H936,O75746 Sequence InterPro Superfamily interpro_homologous_superfamily 259,7,267,143,148,284,162,419,554,169,179,440,57,191,319,444,197,77,593,350 191,444,350,284,259,179,440,554,644,419,77,197,162,7,593,319,148,57,169,267,143 1.7592151429408447,0.9765264378161742,1.2064269794639189,1.4228948856937176,1.5017677751833673,1.803880161059405,0.9875161701203701,0.8167483885125356,0.6450133877649504,1.0416622545332883,2.2514617717609795,1.751667447018552,1.8971479790749635,3.043830354362099,0.7446925671515504,1.293823383957412,1.9590621281540601,2.39928112695771,1.854681789652418,1.4758172511688186,1.992569263975948 3193 Transport vesicle 33 96 3.937860113318209 8.221149620957213e-05 P24390,P50897,Q9UKR5,P04439,Q7L0J3,O43731,Q9BVK6,O95295,O00461,P20020,Q9GZY8,P61026,P49755,Q86Y82,Q15363,O60499,Q9UI14,P49257,O75592,Q9BT78,O43760,P11279,O15126,Q92542,Q15907,O15400,Q9Y3B3,O95249,P05067,O15260,O76024,Q96A57,Q13190 Localization GO Cellular component msigdb_gocc 2,8,266,275,149,26,415,409,34,291,299,430,304,442,61,63,452,447,445,459,78,206,463,211,216,345,95,229,360,245,247,121,253 1249,34,2486,462,2031,715,463,245,345,782,26,2366,78,63,1175,1961,2424,903,445,247,2651,229,409,2182,1521,749,1304,275,360,1677,499,206,669,291,1679,1155,2,3117,1474,1156,2998,1053,447,304,8,890,1203,3161,1085,2962,2659,2604,2315,1979,1130,430,1055,1361,1390,758,2589,1424,253,2265,3077,907,771,2779,61,2294,1632,216,789,149,822,442,688,211,2095,1722,121,459,415,299,664,1147,594,2101,2894,2478,452,266,1673,95,1220,1854 0.1059833465335269,2.605360668935537,-0.6360363435663436,0.9543830980982788,-0.3409024311136362,0.5542099181825546,0.9543830980982788,1.5442857407745552,1.216317751801572,0.4735513630461408,2.6816050945494077,-0.5543007948494578,2.2457277457630314,2.346058243177083,0.15301100508827867,-0.303787854117314,-0.5948794930148794,0.34734463722339803,0.9765264378161742,1.5358542924197818,-0.7848314137948916,1.6104756568747511,1.05233382643295,-0.43590826117893794,-0.05719278632694883,0.5142163574940924,0.07415070895816572,1.4495286247621895,1.1865067348823226,-0.14270834812699967,0.9094287765563077,1.7057429944746445,0.6194206088649225,1.3959088234962316,-0.14270834812699967,0.1684982022009186,3.21572160468917,-1.778616500027411,-0.023739075165896593,0.1684982022009186,-1.3068387009445777,0.22952714396117282,0.9765264378161742,1.3408498426869389,3.0232917146470886,0.36168996784734275,0.1374300649717309,-2.3972018839891502,0.21440615544338357,-1.2051532199617174,-0.7848314137948916,-0.7201373856155233,-0.51428752530657,-0.303787854117314,0.1838925440088085,1.0093338760985888,0.22952714396117282,0.04192461851956566,0.02566161901174243,0.5007368375870117,-0.6988844633124501,0.009297339019232754,1.5188836640650665,-0.4748273403029004,-1.5204378296208023,0.34734463722339803,0.48718206135466036,-0.9185947277776126,2.3514587661376916,-0.494489054305589,-0.1081741936250891,1.6586937760640963,0.4735513630461408,1.952285648216789,0.4321969562595515,0.9875161701203701,0.5935493889180543,1.682361685022864,-0.3596472519831671,-0.16014273539632354,2.1206472108366774,0.9654822230844401,1.05233382643295,1.38683389940539,0.6322515068949177,0.1838925440088085,0.7446925671515504,-0.3596472519831671,-1.0585470825916556,-0.6153848387722859,0.9765264378161742,1.4758172511688186,-0.12538587769838372,2.1991455126433834,0.1374300649717309,-0.23102262249362931 3193 Vacuole 76 214 3.913504006131215 9.096639060057754e-05 Q9UIQ6,Q9BTY2,Q9H7Z7,P51798,P50897,Q14108,P61019,Q6IAA8,P42785,O75503,Q8WTV0,Q8IY95,Q92820,P38571,Q5BJF2,P10253,P07602,Q8NHP8,Q16625,Q9NZJ7,O14773,P53634,Q86YV9,Q9H2V7,Q96GC9,P38435,Q9NX40,O00584,Q15165,Q8N511,P08195,Q13217,Q9UBR2,Q9UNK0,O43681,Q13510,Q96RL7,P04062,Q8NF37,Q8IV08,Q14849,Q9UMR5,Q8NCC3,Q9UHD9,P13473,Q07065,P17900,Q93050,P11279,P16278,Q92542,P11117,O75955,Q9Y487,O15400,O95721,Q969Q5,P10619,P15586,P06865,Q9Y371,P42892,P42345,Q9UHG3,Q99538,Q15043,P61916,Q9HC07,P06280,P27105,O15260,Q13137,Q9BTU6,Q96A57,Q9NQX7,P54802 Localization GO Cellular component msigdb_gocc 516,257,393,383,8,9,520,523,136,139,141,399,529,526,144,145,20,21,532,148,150,402,412,155,156,157,158,285,33,161,417,549,293,429,557,45,178,53,181,184,58,188,193,325,72,73,79,208,206,82,211,85,338,88,345,472,226,98,225,224,487,100,500,105,365,241,491,116,244,115,245,504,507,121,127,126 2301,1013,285,765,916,150,767,2033,245,345,1787,557,2366,1253,957,623,2002,2348,1412,139,338,2702,472,749,1384,888,53,591,815,244,224,1522,2137,2368,20,584,1413,1387,417,1559,1927,1677,796,145,98,85,2351,1895,206,72,1258,225,82,3073,79,1444,1155,2880,693,2547,3066,115,3117,2185,2138,3030,1972,865,962,157,526,2998,1448,866,500,136,1081,100,2494,694,1035,2683,2624,670,8,2920,1528,1530,890,3161,383,1085,2684,402,1054,1086,126,2584,2315,1038,2376,2163,520,1055,2316,1361,491,2407,1532,2042,1745,818,2589,819,2639,1391,3025,73,1092,2193,2116,1424,2499,504,549,45,1537,9,1751,868,58,241,33,986,532,144,523,789,660,412,184,399,161,2148,193,181,2874,21,689,141,2333,1271,211,529,208,226,121,1063,560,1511,824,1723,1064,156,949,178,2569,1295,365,1350,1487,883,1025,507,257,3189,1066,1616,1100,859,1881,1351,155,393,2842,827,116,1147,2875,127,1148,158,2984,148,2674,1493,1298,1698,1996,293,325,105,2151,516,1850,2177,188,1959,429,2635,714,487,88,1439 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3193 vesicles 56 167 3.911327617626714 9.179015959182024e-05 O95470,Q9UM00,O00264,Q15125,Q9UKR5,Q8IY95,P04439,P53985,Q9H2V7,O00767,P20020,Q9UNK0,P61026,P49755,Q8NF37,Q86Y82,O15173,Q15363,O60499,Q9UI14,P49257,Q15904,O43808,P13473,Q93050,Q86UL3,P11279,O96005,P02786,O15126,Q15392,Q969V3,O14653,Q15907,O15400,O60476,Q8IZA0,O15258,Q9Y371,O95249,Q5VW38,Q969E2,P42345,O15127,Q10713,Q9UBF8,Q06136,O75845,P05023,Q9Y5X3,Q8IXU6,Q9BTU6,O95674,Q9Y3E0,O15269,P51798 Localization OpenCell Localization opencell_localization 128,385,258,131,266,399,275,407,155,416,291,429,430,304,181,442,56,61,63,452,447,323,444,72,208,334,206,81,209,463,84,212,462,216,345,346,93,355,487,229,101,358,500,106,236,496,110,238,363,373,246,507,377,250,252,383 258,1440,1249,864,2541,416,2486,462,2346,767,1331,715,463,106,3037,56,355,252,345,444,346,2104,63,957,582,2348,903,238,2651,229,1647,128,377,81,888,209,275,363,3108,1677,612,206,2403,72,1732,291,1154,1679,693,2309,564,1128,2998,866,500,2109,655,447,304,2467,2624,1181,890,383,2638,2659,407,1086,2604,2080,2315,2375,963,520,1130,430,1055,2316,2190,1361,1390,758,2407,2589,1391,110,236,1058,1537,868,1752,1903,1505,131,771,61,84,2294,1632,788,565,323,216,2561,101,2629,2504,660,822,334,442,1876,246,399,93,1510,1991,1613,1583,181,2333,1480,1880,208,358,1812,212,971,1063,2802,1064,949,1487,3078,3035,507,826,664,1351,705,930,155,1952,2875,860,1148,1493,1298,2101,496,2175,2151,452,2953,830,266,831,2716,385,2177,1959,429,487,250,1888,373,1220 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3193 Organophosphate ester transport 16 25 3.900713905124933 9.590944023751824e-05 Q9BSK2,P12235,Q6NUK1,O43808,Q8TDW0,Q9H2D1,Q14108,Q8WTV0,Q08722,P08183,P12236,Q99808,P05141,Q8TB61,Q96GC9,Q9HC21 Processes and pathways GO Biological process msigdb_gobp 162,259,419,444,484,7,9,141,306,176,179,372,284,89,156,319 444,284,176,259,179,2309,1931,833,866,1602,491,306,9,419,660,89,484,141,156,372,162,826,7,319,1493 0.9765264378161742,1.4228948856937176,1.8112225085127378,1.5017677751833673,1.803880161059405,-0.51428752530657,-0.28541547461577405,0.4182557487269513,0.39013449402256833,-0.09107218097239303,0.9207519138862322,1.3408498426869389,3.0232917146470886,1.0416622545332883,0.6322515068949177,2.2225958317358057,0.9320183829658302,1.9991966569128934,1.9180197862656285,1.1663992693165688,1.8971479790749635,0.4321969562595515,3.043830354362099,1.293823383957412,-0.023739075165896593 3193 Azurophil granule membrane 11 23 3.864699896789758 0.0001112258680764 P42785,P13473,Q07065,P11279,P10253,Q92542,P07602,Q8NF37,Q9NZJ7,P27105,Q9NQX7 Localization GO Cellular component msigdb_gocc 136,72,73,206,145,211,20,181,148,115,127 245,623,2002,2348,472,20,145,206,72,115,1448,136,1530,1085,73,523,181,211,883,859,127,148,1493 1.5442857407745552,0.682890738977402,-0.32228307221127694,-0.5342242617338631,0.9432286304255554,2.762496989040066,1.9658133945446885,1.7057429944746445,2.291063262623579,2.132957634741071,-0.007169221259632773,2.0384546855538916,-0.05719278632694883,0.21440615544338357,2.28546270022205,0.8866106862369233,1.7965090219596693,1.682361685022864,0.3759530057373177,0.4042351666901161,2.095763221365341,1.9590621281540601,-0.023739075165896593 3193 Endoplasmic reticulum golgi intermediate compartment membrane 19 25 3.8628133511226106 0.0001120886492669 P24390,P61019,P53634,Q03518,Q9BVK6,Q96GC9,Q8N511,Q9UBR2,P49755,Q15363,P49257,Q15904,P51572,O14653,Q9Y3B3,Q9Y3A6,O15260,Q9Y282,Q13190 Localization GO Cellular component msigdb_gocc 2,520,402,152,415,156,161,293,304,61,447,323,327,462,95,498,245,119,253 462,245,782,903,2,2185,447,304,327,402,520,152,574,253,61,323,161,156,415,2276,664,293,119,498,95 0.9543830980982788,1.5442857407745552,0.4735513630461408,0.34734463722339803,3.21572160468917,-0.43590826117893794,0.9765264378161742,1.3408498426869389,1.2650915011001496,1.0735225288658525,0.8866106862369233,1.9386564503168657,0.7810014179820873,1.5188836640650665,2.3514587661376916,1.284289708677259,1.8971479790749635,1.9180197862656285,1.05233382643295,-0.4748273403029004,0.6322515068949177,1.3959088234962316,2.1268132851345656,0.9207519138862322,2.1991455126433834 3193 Vascular skin abnormality 38 117 3.8228884814999953 0.0001318974420416 Q15125,Q14108,P98194,Q9H1A4,Q9UBM7,Q9NX14,Q96L58,P51812,Q16625,Q86YV9,P38435,O75306,P21964,Q6NUK1,P21912,P04062,Q9NWM8,Q13126,P53701,P49257,O75844,P00403,Q8NCH0,P51648,P04066,P16278,Q14739,Q9Y487,P22830,Q8IZA0,P10619,O15360,Q06136,Q5T2R2,P06280,Q9BUR4,Q86V48,P51798 Drugs and Diseases Human Phenotype Ontology msigdb_hp 131,9,522,514,400,530,272,527,532,412,157,543,288,419,553,53,182,55,317,447,67,195,70,71,591,82,210,88,596,93,98,481,110,493,244,379,378,383 1279,2303,481,1554,1705,756,1858,543,2035,67,1000,2400,1648,195,1304,643,53,591,244,1558,1650,98,604,3047,2741,2284,82,1623,653,1224,3065,553,288,1598,596,2185,1600,2138,2760,1128,1018,962,2657,157,2998,1973,1180,685,447,1084,1388,71,383,527,317,2604,1978,1088,2113,522,2471,1534,2887,110,709,2262,55,3050,9,2526,1287,210,2323,131,1288,1289,1632,788,532,2561,493,1774,419,1209,1612,2730,1635,378,412,93,989,70,1837,2611,1401,3041,1777,272,777,2239,883,379,1272,2861,514,2061,182,530,2924,400,1494,934,2719,2480,88,754,1821 0.09011573382996567,-0.51428752530657,0.9320183829658302,-0.07407874008591195,-0.16014273539632354,0.5007368375870117,-0.24903411518852805,0.8402742865808962,-0.3409024311136362,2.329750012077,0.27435692511880505,-0.5745186791895069,-0.12538587769838372,1.751667447018552,0.07415070895816572,0.6450133877649504,2.4355304023078563,0.7446925671515504,1.5526815978228736,-0.07407874008591195,-0.12538587769838372,2.1872987787678158,0.7201675789757652,-1.4386772460322241,-0.8733409382481655,-0.494489054305589,2.2399742438327923,-0.1081741936250891,0.6322515068949177,0.12175448251162654,-1.492956015355766,0.8167483885125356,1.4049437781239236,-0.09107218097239303,0.7324623353077244,-0.43590826117893794,-0.09107218097239303,-0.39751866108604983,-0.8958829370602809,0.1838925440088085,0.25950170179577764,0.30380731745916084,-0.7848314137948916,1.9041316359550924,-1.3068387009445777,-0.303787854117314,0.15301100508827867,0.5935493889180543,0.9765264378161742,0.21440615544338357,0.02566161901174243,2.2966451596705606,1.1358809033740525,0.8751148153965543,1.3033138565109923,-0.7201373856155233,-0.303787854117314,0.21440615544338357,-0.3785188752723304,0.8866106862369233,-0.6153848387722859,-0.05719278632694883,-1.0585470825916556,2.1512615372917634,0.5673949130081869,-0.4748273403029004,2.4045094117547388,-1.4386772460322241,3.0232917146470886,-0.656835659642823,0.09011573382996567,1.6979807301199143,-0.51428752530657,2.070521741578072,0.09011573382996567,0.09011573382996567,-0.1081741936250891,0.4735513630461408,0.863560440465855,-0.6777844648834328,0.9207519138862322,-0.1953518618147444,1.0416622545332883,0.1374300649717309,-0.09107218097239303,-0.8509667351664257,-0.1081741936250891,1.1461017884280336,1.05233382643295,2.205038320950641,0.2891251966313216,2.302208489423922,-0.23102262249362931,-0.7201373856155233,0.02566161901174243,-1.4118743308181245,-0.1953518618147444,1.4583294958454196,0.48718206135466036,-0.4553008972742839,0.3759530057373177,1.1461017884280336,0.1059833465335269,-1.011180888611287,0.8980485194817284,-0.3409024311136362,1.7965090219596693,0.8751148153965543,-1.1309875400384923,1.0840404415884148,-0.023739075165896593,0.3329162614491058,-0.8287583635800084,-0.6153848387722859,2.2284083926639537,0.5142163574940924,-0.213128942203161 3193 Ion transport 30 51 3.7891787925292943 0.0001511461051957 Q9UM00,Q9Y277,P98194,Q9C0H2,O96008,Q96S66,Q8NE01,P20020,P06576,Q9BPX6,P55011,O75964,P45880,P56385,P21796,Q9Y6M7,O95202,Q15904,P16615,Q93050,P24539,Q8TAD4,Q9Y487,Q8TDW0,P56134,Q9BVC6,P05023,Q15043,Q6P4Q7,P51798 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 385,135,522,11,525,403,280,291,552,301,558,47,48,305,51,189,190,323,196,208,83,86,88,484,618,495,363,241,254,383 3036,1281,47,190,525,363,1676,552,2722,196,291,693,2547,51,83,1333,983,962,2998,48,2932,3161,383,798,558,618,305,1361,522,2117,241,323,3026,254,280,724,86,484,208,403,301,495,11,627,705,2151,385,135,88,2211,189 -1.4118743308181245,0.09011573382996567,2.515439795372476,1.7667329517528663,0.8751148153965543,1.176476578042439,-0.14270834812699967,0.8167483885125356,-0.8509667351664257,1.751667447018552,1.3959088234962316,0.5805078633245453,-0.6777844648834328,2.5007588066882245,2.2399742438327923,0.05808732403364699,0.2891251966313216,0.30380731745916084,-1.3068387009445777,2.515439795372476,-1.1555145615983378,-2.3972018839891502,1.1358809033740525,0.45984406883424556,0.8048943132507087,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.8866106862369233,-0.3785188752723304,1.5693674826960398,1.284289708677259,-1.3589269339837995,1.5188836640650665,1.4406894094750298,0.5542099181825546,2.2342011612850494,0.9320183829658302,1.7057429944746445,1.0735225288658525,1.350128868152097,0.9207519138862322,2.984818292512709,0.682890738977402,0.5805078633245453,-0.39751866108604983,1.1358809033740525,2.051351117777622,2.2284083926639537,-0.43590826117893794,1.7742210599427393 3193 Lipid localization 30 69 3.788301847859586 0.0001516804982619 Q9BQE5,Q14108,Q6IAA8,Q8WTV0,P07602,Q9NZJ7,Q9H2V7,Q96GC9,P35610,P23786,Q14534,P08183,Q99720,P04062,Q86Y82,P31751,Q14849,Q9UJZ1,Q9H6V9,O43772,O43808,P30536,P07686,P17900,Q9BUR5,P28288,P61916,P35790,O15260,O95674 Processes and pathways GO Biological process msigdb_gobp 1,9,523,141,20,148,155,156,410,167,297,176,50,53,442,564,58,577,62,191,444,200,584,79,213,473,491,242,245,377 666,3169,2033,245,191,444,1175,2182,1048,377,2878,2653,53,692,1522,20,584,2601,176,959,612,2460,1966,79,2309,1931,167,473,200,564,1202,833,410,242,1602,923,491,2043,2887,9,297,58,1987,523,1209,660,442,3175,141,156,50,1,1026,213,826,1324,2861,155,803,62,1148,148,1493,1461,1070,577,2699,1959,1439 0.6194206088649225,-2.6169954275388214,-0.3409024311136362,1.5442857407745552,1.7592151429408447,0.9765264378161742,0.15301100508827867,-0.43590826117893794,0.22952714396117282,1.1461017884280336,-1.0585470825916556,-0.7848314137948916,2.4355304023078563,0.5805078633245453,-0.05719278632694883,2.762496989040066,0.7568588077238091,-0.7201373856155233,1.8112225085127378,0.30380731745916084,0.7078077588474234,-0.6153848387722859,-0.303787854117314,2.2457277457630314,-0.51428752530657,-0.28541547461577405,1.8618274754931423,0.9432286304255554,1.7364816398521126,0.7929788244184839,0.1374300649717309,0.4182557487269513,1.05233382643295,1.5610421002753638,-0.09107218097239303,0.3329162614491058,0.9207519138862322,-0.3409024311136362,-1.0585470825916556,3.0232917146470886,1.38683389940539,2.394036011434074,-0.303787854117314,0.8866106862369233,0.1374300649717309,0.6322515068949177,0.9875161701203701,-2.85051601606499,1.9991966569128934,1.9180197862656285,2.5056676046326203,3.268320628293502,0.25950170179577764,1.682361685022864,0.4321969562595515,0.07415070895816572,-1.011180888611287,1.9249245939305628,0.45984406883424556,2.3514587661376916,0.1838925440088085,1.9590621281540601,-0.023739075165896593,-0.007169221259632773,0.22952714396117282,0.7810014179820873,-0.8067138905481915,-0.28541547461577405,0.009297339019232754 3193 Carboxylic acid transport 24 33 3.783530472200776 0.0001546193844146 Q9H2D1,Q02978,Q9Y619,P07602,Q7L0J3,Q9NZJ7,P53985,P08195,Q96NB2,Q9UJS0,O75915,P55011,Q9H2J7,P53007,Q15758,Q9UBX3,P04083,Q9BQT8,Q9H936,Q9H9B4,O75746,P28288,Q8TDW0,O60831 Processes and pathways GO Biological process msigdb_gobp 7,644,267,20,149,148,407,417,546,169,551,558,705,440,565,57,692,197,593,601,350,473,484,489 2346,2031,489,350,551,692,1078,20,417,2460,473,833,866,440,407,558,2555,644,752,565,1209,149,484,546,197,7,705,593,601,148,57,169,267 -0.5342242617338631,-0.3409024311136362,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.5805078633245453,0.21440615544338357,2.762496989040066,1.0416622545332883,-0.6153848387722859,0.9432286304255554,0.4182557487269513,0.39013449402256833,0.9875161701203701,1.0629537868319574,0.8048943132507087,-0.6777844648834328,0.6450133877649504,0.5142163574940924,0.7929788244184839,0.1374300649717309,1.952285648216789,0.9320183829658302,0.8402742865808962,1.751667447018552,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,1.9590621281540601,2.39928112695771,1.854681789652418,1.4758172511688186 3193 Active ion transmembrane transporter activity 28 41 3.748288838634531 0.0001780451459203 P12235,Q9UDW1,Q02978,P98194,Q96ES6,P05141,P08195,P08574,P20020,Q00325,P47985,P06576,P55011,Q9BXP2,P12236,Q9H2J7,P53007,Q9Y6M7,O95202,P00403,P16615,Q9H936,P13073,P05023,Q7KZN9,Q9HD20,Q15043,P51798 Functions GO Molecular function msigdb_gomf 259,6,644,522,142,284,417,668,291,554,679,552,558,433,179,705,440,189,190,195,196,593,109,363,112,113,241,383 190,195,363,1676,284,552,417,668,1153,259,179,109,196,291,981,693,2547,1284,833,962,2998,866,679,3161,383,440,558,1361,522,554,644,241,112,142,433,705,593,113,6,2151,189 1.7667329517528663,1.751667447018552,1.176476578042439,-0.14270834812699967,1.4228948856937176,0.8167483885125356,1.0416622545332883,0.6194206088649225,0.1684982022009186,1.5017677751833673,1.803880161059405,2.1512615372917634,1.751667447018552,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,0.09011573382996567,0.4182557487269513,0.30380731745916084,-1.3068387009445777,0.39013449402256833,0.6065201023101452,-2.3972018839891502,1.1358809033740525,0.9875161701203701,0.8048943132507087,0.04192461851956566,0.8866106862369233,0.8167483885125356,0.6450133877649504,1.5693674826960398,2.1451816415421097,1.992569263975948,1.0093338760985888,0.5805078633245453,0.7446925671515504,2.1451816415421097,3.1003852237037637,-0.39751866108604983,1.7742210599427393 3193 Organic acid transport 28 45 3.737702986909624 0.0001857091443551 Q9H2D1,Q02978,Q9Y619,Q7L0J3,P53985,P08195,Q96NB2,Q6P4A7,P23786,Q9UJS0,O75915,P55011,P08183,Q9H2J7,P31751,P53007,Q15758,Q9UBX3,O43772,O43808,Q9BQT8,Q9H936,Q9H9B4,O75746,P28288,Q8TDW0,P11166,O60831 Processes and pathways GO Biological process msigdb_gobp 7,644,267,149,407,417,546,166,167,169,551,558,176,705,564,440,565,57,191,444,197,593,601,350,473,484,612,489 2346,2031,191,444,489,350,551,1048,2653,692,1078,2601,176,417,959,612,2460,167,473,564,1202,833,866,923,440,407,558,2555,644,752,565,1209,166,149,484,546,197,7,705,593,601,57,169,2699,267 -0.5342242617338631,-0.3409024311136362,1.7592151429408447,0.9765264378161742,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.22952714396117282,-0.7848314137948916,0.5805078633245453,0.21440615544338357,-0.7201373856155233,1.8112225085127378,1.0416622545332883,0.30380731745916084,0.7078077588474234,-0.6153848387722859,1.8618274754931423,0.9432286304255554,0.7929788244184839,0.1374300649717309,0.4182557487269513,0.39013449402256833,0.3329162614491058,0.9875161701203701,1.0629537868319574,0.8048943132507087,-0.6777844648834328,0.6450133877649504,0.5142163574940924,0.7929788244184839,0.1374300649717309,1.8760367688861144,1.952285648216789,0.9320183829658302,0.8402742865808962,1.751667447018552,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.39928112695771,1.854681789652418,-0.8067138905481915,1.4758172511688186 3193 Inner mitochondrial membrane organization 18 21 3.721507149650681 0.0001980372576184 Q9Y512,Q9P0J0,Q6UXV4,Q53H12,Q5XKP0,Q13505,Q9Y5J9,Q8WWC4,Q9H3K2,Q9NX63,O75431,P17152,Q9Y5L4,Q9BUR5,Q9NVH1,O95202,O60313,Q16891 Processes and pathways GO Biological process msigdb_gobp 290,129,352,387,260,36,488,357,234,461,583,592,602,213,408,190,221,318 221,583,1152,190,592,2465,36,318,387,260,352,357,213,234,408,461,129,677,290,488,602 1.6266810625618235,0.7568588077238091,0.1684982022009186,1.7667329517528663,0.7446925671515504,-0.6153848387722859,2.596136262438205,1.293823383957412,1.125611440557737,1.5017677751833673,1.2064269794639189,1.1964900873490003,1.682361685022864,1.6023224295792171,1.0629537868319574,0.9654822230844401,2.0831876730587275,0.6194206088649225,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 Metal ion transmembrane transporter activity 14 24 3.708349890217375 0.000208614269507 Q9UM00,P08195,P20020,P16615,P98194,P05023,Q9BXP2,Q9HD20,Q15043,Q9HC07,Q8TAD4,Q6P4Q7,Q9Y6M7,O95202 Functions GO Molecular function msigdb_gomf 385,417,291,196,522,363,433,113,241,116,86,254,189,190 190,363,1676,1522,1387,417,196,291,558,941,522,1605,241,254,724,86,1400,433,859,705,116,113,385,189 1.7667329517528663,1.176476578042439,-0.14270834812699967,-0.05719278632694883,0.02566161901174243,1.0416622545332883,1.751667447018552,1.3959088234962316,0.8048943132507087,0.3184040786732402,0.8866106862369233,-0.09107218097239303,1.5693674826960398,1.5188836640650665,0.5542099181825546,2.2342011612850494,0.02566161901174243,1.0093338760985888,0.4042351666901161,0.5805078633245453,2.132957634741071,2.1451816415421097,1.1358809033740525,1.7742210599427393 3193 Divalent inorganic cation homeostasis 26 54 3.700534432991782 0.000215145882402 Q96TC7,Q9UM00,P98194,P62942,Q7L0J3,Q8NE01,Q16611,P20020,Q8IYU8,Q9BPX6,Q96A33,Q16891,Q9UJZ1,O95202,P16615,P51572,P07686,Q8TAD4,Q8WWC4,P05067,Q9HD20,Q15043,Q9HC07,O76024,P62258,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 384,385,522,276,149,280,544,291,425,301,174,318,577,190,196,327,584,86,357,360,113,241,116,247,633,254 1013,916,1621,2488,247,190,1647,1676,360,1596,584,1387,1200,2352,1443,196,1623,1501,291,3117,2185,3091,1081,327,1799,633,276,2378,522,1605,2499,2381,944,241,2779,544,318,254,149,2330,425,280,724,86,357,174,898,384,301,116,113,577,385,677 0.25950170179577764,0.3329162614491058,-0.1081741936250891,-0.6360363435663436,1.5358542924197818,1.7667329517528663,-0.12538587769838372,-0.14270834812699967,1.1865067348823226,-0.09107218097239303,0.7568588077238091,0.02566161901174243,0.1374300649717309,-0.5342242617338631,-0.007169221259632773,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,-1.778616500027411,-0.43590826117893794,-1.6042899045333228,0.21440615544338357,1.2650915011001496,-0.213128942203161,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,-0.09107218097239303,-0.6360363435663436,-0.5543007948494578,0.3184040786732402,1.5693674826960398,-0.9185947277776126,0.8402742865808962,1.293823383957412,1.5188836640650665,1.952285648216789,-0.51428752530657,1.0201626829533696,1.4406894094750298,0.5542099181825546,2.2342011612850494,1.1964900873490003,1.825821535867474,0.36168996784734275,1.1358809033740525,1.350128868152097,2.132957634741071,2.1451816415421097,0.7810014179820873,1.1358809033740525,0.6194206088649225 3193 Lytic vacuole organization 9 24 3.693140154801955 0.0002215018635149 P50897,Q14108,O75503,P10253,Q9HC07,P04062,P11117,O14773,P54802 Processes and pathways GO Biological process msigdb_gobp 8,9,139,145,116,53,85,150,126 1013,150,139,409,53,584,145,85,500,8,890,126,1055,964,9,868,523,161,1063,949,116,1148,1298,1958 0.25950170179577764,1.945483805688231,2.0123785518790727,1.05233382643295,2.4355304023078563,0.7568588077238091,1.9658133945446885,2.2342011612850494,0.9094287765563077,3.0232917146470886,0.36168996784734275,2.095763221365341,0.22952714396117282,0.30380731745916084,3.0232917146470886,0.39013449402256833,0.8866106862369233,1.8971479790749635,0.22952714396117282,0.3184040786732402,2.132957634741071,0.1838925440088085,0.09011573382996567,-0.28541547461577405 3193 membrane trafficking regulatory protein 6 18 3.685826354628184 0.0002279617496501 P24390,P13473,Q14108,Q8WTV0,O43760,O43731 Functions Panther Protein class panther_protein_class 2,72,9,141,78,26 1383,1280,26,78,1647,206,72,2,9,1505,2779,141,734,1063,1947,1881,1493,1298 0.02566161901174243,0.09011573382996567,2.6816050945494077,2.2457277457630314,-0.12538587769838372,1.7057429944746445,2.291063262623579,3.21572160468917,3.0232917146470886,-0.04041324981336907,-0.9185947277776126,1.9991966569128934,0.5409522516865753,0.22952714396117282,-0.28541547461577405,-0.24903411518852805,-0.023739075165896593,0.09011573382996567 3193 Membrane lipid biosynthetic process 12 20 3.6760415254701977 0.0002368809812007 O95470,Q53H12,Q16880,Q9P035,Q13510,Q9H490,Q06136,P04062,Q96G23,Q99805,Q8NBX0,O15269 Processes and pathways GO Biological process msigdb_gobp 128,387,140,203,45,366,110,53,118,343,154,252 252,1198,756,128,53,2309,110,45,140,387,154,468,1401,118,663,343,366,753,203,1493 1.5188836640650665,0.1374300649717309,0.5007368375870117,2.0894866813375814,2.4355304023078563,-0.51428752530657,2.1512615372917634,2.5348046058833917,2.0123785518790727,1.125611440557737,1.9318034306318732,0.9543830980982788,0.02566161901174243,2.1268132851345656,0.6322515068949177,1.2261627415331837,1.176476578042439,0.5142163574940924,1.7288431475403072,-0.023739075165896593 3193 Steroid binding 11 19 3.671549480191489 0.0002410843901539 O00264,Q14108,P30536,P05023,P45880,P21796,P04062,O15173,Q14849,P38435,P35610 Functions GO Molecular function msigdb_gomf 258,9,200,363,48,51,53,56,58,157,410 258,2033,56,1015,53,363,1387,51,2309,1931,200,410,157,48,491,9,58,826,1324 1.5017677751833673,-0.3409024311136362,2.39928112695771,0.25950170179577764,2.4355304023078563,1.176476578042439,0.02566161901174243,2.5007588066882245,-0.51428752530657,-0.28541547461577405,1.7364816398521126,1.05233382643295,1.9041316359550924,2.515439795372476,0.9207519138862322,3.0232917146470886,2.394036011434074,0.4321969562595515,0.07415070895816572 3193 Steroid metabolic process 30 67 3.635718139600881 0.0002772073022077 O95470,Q9BQE5,Q15125,Q9UKR5,Q6IAA8,Q8WTV0,Q9UBM7,P38435,P35610,Q53GQ0,Q14534,Q16850,Q13510,P04062,Q14849,Q8NBQ5,P49748,P30536,P04035,Q14739,Q15392,P28288,P37268,P05067,Q15800,Q99538,O75845,P05023,P61916,P16435 Processes and pathways GO Biological process msigdb_gobp 128,1,131,266,523,141,400,157,410,286,297,170,45,53,58,324,455,200,205,210,84,473,99,360,107,365,238,363,491,248 766,2033,238,1015,128,888,205,53,363,360,3146,2403,2077,2957,248,2309,1931,2704,2883,473,200,2705,410,99,157,526,2706,655,455,2217,850,2684,2948,491,2043,2981,2320,45,3120,297,210,58,1903,131,2872,84,1577,1939,788,107,170,286,1987,523,324,141,2818,365,2839,1,1324,2149,400,1461,1589,266,2877 0.48718206135466036,-0.3409024311136362,1.5776579775269348,0.25950170179577764,2.0894866813375814,0.36168996784734275,1.7057429944746445,2.4355304023078563,1.176476578042439,1.1865067348823226,-2.1564896067692816,-0.5745186791895069,-0.3596472519831671,-1.2051532199617174,1.5358542924197818,-0.51428752530657,-0.28541547461577405,-0.8287583635800084,-1.0585470825916556,0.9432286304255554,1.7364816398521126,-0.8287583635800084,1.05233382643295,2.1872987787678158,1.9041316359550924,0.8751148153965543,-0.8287583635800084,0.6322515068949177,0.9654822230844401,-0.4553008972742839,0.4042351666901161,-0.8067138905481915,-1.180235642836601,0.9207519138862322,-0.3409024311136362,-1.2555878176142559,-0.51428752530657,2.5348046058833917,-1.8085693165877301,1.38683389940539,1.6979807301199143,2.394036011434074,-0.2671646500903092,2.070521741578072,-1.0347727466327314,2.2399742438327923,-0.07407874008591195,-0.28541547461577405,0.4735513630461408,2.163357703140536,1.8475085220023033,1.413939040620315,-0.303787854117314,0.8866106862369233,1.284289708677259,1.9991966569128934,-0.9645358333127365,1.176476578042439,-0.9877693062177954,3.268320628293502,0.07415070895816572,-0.39751866108604983,1.0840404415884148,-0.007169221259632773,-0.07407874008591195,1.4758172511688186,-1.0347727466327314 3193 Molecular transducer activity 14 31 3.6259881518672983 0.0002878585530665 Q4VCS5,Q5KU26,Q14108,P30536,Q8WTV0,Q08722,Q99442,Q99720,Q9BUN8,Q9UGP8,Q15629,O15173,Q15758,Q15375 Functions GO Molecular function msigdb_gomf 418,201,9,200,141,306,432,50,147,571,114,56,565,674 1785,2033,56,1078,1964,669,1155,200,1973,1710,1084,1606,306,1092,1058,9,674,114,565,418,201,2088,141,1062,1400,432,50,147,1883,1353,571 -0.213128942203161,-0.3409024311136362,2.39928112695771,0.21440615544338357,-0.303787854117314,0.6194206088649225,0.1684982022009186,1.7364816398521126,-0.303787854117314,-0.16014273539632354,0.21440615544338357,-0.09107218097239303,1.3408498426869389,0.21440615544338357,0.22952714396117282,3.0232917146470886,0.6194206088649225,2.1390803803002107,0.7929788244184839,1.0416622545332883,1.7364816398521126,-0.3596472519831671,1.9991966569128934,0.22952714396117282,0.02566161901174243,1.0093338760985888,2.5056676046326203,1.9658133945446885,-0.24903411518852805,0.05808732403364699,0.7929788244184839 3193 Organelle fusion 20 49 3.625851542743917 0.000288010790338 Q9Y6C9,O95295,Q16611,Q9UNK0,Q9GZY8,Q8N2A8,Q86Y82,P31751,O60499,Q8NAN2,Q9NX63,P02786,O14653,Q8IWA4,O15400,O60313,O95721,Q12981,O95249,Q13190 Processes and pathways GO Biological process msigdb_gobp 143,409,544,429,299,559,442,564,63,457,461,209,462,218,345,221,472,223,229,253 2301,462,345,221,1857,63,1961,903,769,229,409,472,209,692,785,1522,1927,564,890,1203,1085,1979,1424,223,253,1505,544,968,442,2798,218,559,457,2095,881,1295,299,1351,1244,1148,2027,461,1298,1996,577,1959,429,677,143 -0.51428752530657,0.9543830980982788,1.216317751801572,1.6266810625618235,-0.24903411518852805,2.346058243177083,-0.303787854117314,0.34734463722339803,0.48718206135466036,1.6104756568747511,1.05233382643295,0.9432286304255554,1.6979807301199143,0.5805078633245453,0.4735513630461408,-0.05719278632694883,-0.28541547461577405,0.7929788244184839,0.36168996784734275,0.1374300649717309,0.21440615544338357,-0.303787854117314,0.009297339019232754,1.6266810625618235,1.5188836640650665,-0.04041324981336907,0.8402742865808962,0.30380731745916084,0.9875161701203701,-0.9414783391764264,1.6586937760640963,0.8048943132507087,0.9654822230844401,-0.3596472519831671,0.3759530057373177,0.09011573382996567,1.38683389940539,0.05808732403364699,0.12175448251162654,0.1838925440088085,-0.32228307221127694,0.9654822230844401,0.09011573382996567,-0.303787854117314,0.7810014179820873,-0.28541547461577405,1.0201626829533696,0.6194206088649225,1.992569263975948 3193 Endoplasmic reticulum organization 23 40 3.614654300098064 0.0003007486561488 Q8NHH9,Q8N5M9,O95197,A0FGR8,Q5J8M3,Q9P2W9,O43681,P61026,Q00765,Q96A33,Q9NQC3,Q15363,Q12907,P49257,O15027,Q12981,P46379,Q5JRA6,Q15042,Q9NPA0,Q15629,Q8NFQ8,P57088 Processes and pathways GO Biological process msigdb_gobp 271,279,27,666,550,39,557,430,431,174,59,61,574,447,715,223,351,613,752,239,114,626,255 666,1889,1249,1331,715,557,919,2651,27,1647,351,447,255,430,941,431,574,223,893,752,61,114,550,613,2913,279,909,626,271,174,1026,930,1845,860,239,59,753,1170,1493,39 0.6194206088649225,-0.2671646500903092,0.1059833465335269,0.05808732403364699,0.5542099181825546,0.8048943132507087,0.3329162614491058,-0.7848314137948916,2.6684245539590274,-0.12538587769838372,1.2064269794639189,0.9765264378161742,1.510343999684222,1.0093338760985888,0.3184040786732402,1.0093338760985888,0.7810014179820873,1.6266810625618235,0.36168996784734275,0.5142163574940924,2.3514587661376916,2.1390803803002107,0.8285415486462114,0.7078077588474234,-1.1066521830470757,1.4406894094750298,0.34734463722339803,0.682890738977402,1.4583294958454196,1.825821535867474,0.25950170179577764,0.3329162614491058,-0.23102262249362931,0.4042351666901161,1.5776579775269348,2.3887739794503915,0.5142163574940924,0.1684982022009186,-0.023739075165896593,2.572831939044648 3193 Membrane protein complex 113 277 3.6084329585765658 0.0003080520943037 O60830,Q9UDW1,P51571,Q9NS69,Q6IAA8,Q9C0H2,Q9NX14,O43676,Q8N4H5,P14406,O96008,Q99595,O75306,Q16611,Q13505,O14949,Q5J8M3,Q9P2W9,P06576,P21912,O75964,P45880,Q96CS3,Q9UGP8,P21796,Q9NR28,Q8WXH0,Q96CU9,O60499,O75431,Q8TCT9,Q9NR31,P24539,Q9Y487,O14925,P67812,Q9Y3B3,P22695,P56134,Q9Y5M8,P13073,Q12959,Q96IX5,Q3ZCQ8,Q9P0J0,Q9Y277,P61803,Q96S52,Q9BUN8,P51970,P09669,Q03518,Q9Y4W6,Q14254,P11717,P08574,Q8N511,P12236,P00403,Q9UBV2,P46977,Q93050,P02786,Q92542,Q9BUR5,Q8IWA4,Q12981,O95249,Q15388,Q9NPA0,O15269,Q13190,P12235,Q5XKP0,P62942,P04439,P05141,Q53GQ0,Q9Y512,Q9BPX6,P56385,P49755,Q16891,Q9UBU6,Q15005,Q15904,O75955,O15400,Q6UXV4,Q9H490,P05023,Q8N2K0,Q9Y5X3,P49458,P51798,Q53H12,Q99623,Q96S66,O95168,Q9NVH1,P08195,Q9UNK0,Q8IYU8,Q86Y82,Q9NX63,Q92643,Q8TCJ2,O14653,O95721,Q8TDW0,Q9UH99,P04843,P10321 Localization GO Cellular component msigdb_gocc 5,6,519,10,523,11,530,16,15,18,525,19,543,544,36,37,550,39,552,553,47,48,560,571,51,570,575,60,63,583,80,594,83,88,92,94,95,97,618,108,109,625,637,639,129,135,658,663,147,656,652,152,677,671,669,668,161,179,195,198,204,208,209,211,213,218,223,229,232,239,252,253,259,260,276,275,284,286,290,301,305,304,318,320,322,323,338,345,352,366,363,371,373,374,383,387,388,403,404,408,417,429,425,442,461,468,467,462,472,484,497,490,499 2301,1013,2540,3036,864,2541,832,2486,916,462,2346,92,37,1892,252,1198,345,782,2905,716,16,2366,2104,63,748,957,5,876,543,2424,958,903,583,1412,1557,1281,338,47,1152,2036,690,2702,2651,404,1963,229,847,2182,1521,472,749,525,195,1304,209,275,490,815,1730,363,1676,284,1078,552,1522,417,668,1927,1200,1677,652,499,1153,2458,669,259,179,109,18,1731,770,922,1177,3040,981,693,2547,51,553,1598,97,83,1415,1333,2185,2959,3021,2037,2678,1795,1284,1334,1128,786,1156,983,962,2998,2465,1448,866,1654,2910,48,1227,204,679,2932,1053,1084,374,304,3049,519,383,1085,656,2962,2659,1054,2604,798,2080,2584,2468,2315,618,1038,305,2899,963,1655,1361,941,658,1390,276,926,2407,1532,942,94,2589,152,1607,1572,1092,2193,1424,625,223,2293,253,2265,36,1453,1537,880,671,944,868,1752,322,893,2324,2779,232,2294,1632,323,544,1507,1002,318,639,286,387,550,1317,260,523,352,442,218,425,371,15,161,909,724,2273,467,80,484,2333,575,211,468,2611,208,1401,1063,560,60,1511,1064,637,949,663,403,1350,19,388,1487,3126,2786,301,147,213,3189,11,859,1881,1351,366,1952,1327,2875,239,570,594,10,408,2246,530,461,1170,129,1298,39,2065,2101,2175,320,198,2894,6,571,497,2151,2716,978,429,2479,862,135,714,95,88,677,290,108,373,1220,1439,2211,935 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8244184839,0.9207519138862322,-0.39751866108604983,-0.8287583635800084,0.30380731745916084,1.0201626829533696,-0.6153848387722859,0.4042351666901161,2.051351117777622,0.5673949130081869,2.1991455126433834,2.2284083926639537,0.6194206088649225,1.4049437781239236,2.163357703140536,1.1663992693165688,0.1374300649717309,0.009297339019232754,-0.43590826117893794,0.3329162614491058 3193 Protein targeting to mitochondrion 23 48 3.5990535653424662 0.0003193774059468 Q9P0J0,Q5JRX3,Q53H12,O60830,O95831,Q9NS69,P55786,Q8N4H5,Q99595,Q9Y512,O14737,Q9GZY8,O00165,P49257,P51572,P30536,O14925,Q9Y5J9,Q9Y371,Q99797,Q15388,Q10713,O43615 Processes and pathways GO Biological process msigdb_gobp 129,512,387,5,389,10,396,15,19,290,294,299,303,447,327,200,92,488,487,359,232,236,376 303,1279,294,92,716,376,5,2072,1152,769,2636,718,2829,389,525,1413,2458,2287,200,2832,447,2467,327,396,2963,236,232,2168,639,387,512,968,15,928,1909,19,359,299,1327,10,129,1884,3005,730,487,290,488,602 1.3408498426869389,0.09011573382996567,1.38683389940539,2.2109109040904884,0.5542099181825546,1.1461017884280336,3.1165747016179965,-0.3596472519831671,0.1684982022009186,0.48718206135466036,-0.7631090610942425,0.5542099181825546,-0.9877693062177954,1.1152930343193794,0.8751148153965543,0.009297339019232754,-0.6153848387722859,-0.494489054305589,1.7364816398521126,-0.9877693062177954,0.9765264378161742,-0.6153848387722859,1.2650915011001496,1.1049253152266847,-1.2051532199617174,1.5859138151123813,1.6023224295792171,-0.41664798954862137,0.6577068359941382,1.125611440557737,0.8980485194817284,0.30380731745916084,2.9120109684113684,0.3329162614491058,-0.2671646500903092,2.8113998714497686,1.1964900873490003,1.38683389940539,0.07415070895816572,3.0024397548003465,2.0831876730587275,-0.24903411518852805,-1.3068387009445777,0.5542099181825546,0.9320183829658302,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 Metal ion transport 39 96 3.5310116840030656 0.0004139734610628 Q9UM00,P98194,O75027,P62942,Q9Y4W6,Q96GC9,Q16611,P08195,P46934,P20020,Q8IYU8,P55011,Q9BPX6,Q9BXP2,P21796,Q9H2J7,O15173,Q9Y6M7,Q9UJZ1,O95202,P46459,O75844,P16615,P30536,P02786,Q8NE86,Q9H9B4,Q8TAD4,Q15907,Q8WWC4,P05023,Q9HD20,Q15043,Q9HC07,P27105,Q12959,O76024,P62258,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 385,522,397,276,677,156,544,417,35,291,425,558,301,433,51,705,56,189,577,190,694,67,196,200,209,724,601,86,216,357,363,113,241,116,115,625,247,633,254 1249,2346,999,56,1076,1125,2488,397,1222,2072,67,247,190,2426,209,1730,363,1676,1078,1596,1522,1387,417,1792,2403,2352,196,1623,1501,291,3065,51,1358,115,3117,200,3091,865,1128,1081,694,35,1227,1181,798,558,1089,941,633,276,2378,522,1605,2589,1132,2320,1423,2836,2193,2499,625,1425,2381,2412,2225,241,216,544,1002,254,2330,425,2838,1991,724,86,357,1400,156,898,2786,301,433,859,801,705,601,116,113,735,2478,577,385,2903,677,189 0.1059833465335269,-0.5342242617338631,0.27435692511880505,2.39928112695771,0.21440615544338357,0.1838925440088085,-0.6360363435663436,1.0945079100252835,0.12175448251162654,-0.3596472519831671,2.329750012077,1.5358542924197818,1.7667329517528663,-0.5948794930148794,1.6979807301199143,-0.177690185818539,1.176476578042439,-0.14270834812699967,0.21440615544338357,-0.09107218097239303,-0.05719278632694883,0.02566161901174243,1.0416622545332883,-0.213128942203161,-0.5745186791895069,-0.5342242617338631,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,-1.492956015355766,2.5007588066882245,0.04192461851956566,2.132957634741071,-1.778616500027411,1.7364816398521126,-1.6042899045333228,0.39013449402256833,0.1838925440088085,0.21440615544338357,0.5805078633245453,2.596136262438205,0.12175448251162654,0.15301100508827867,0.45984406883424556,0.8048943132507087,0.21440615544338357,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,-0.09107218097239303,-0.6988844633124501,0.1838925440088085,-0.51428752530657,0.009297339019232754,-0.9877693062177954,-0.43590826117893794,-0.6360363435663436,0.682890738977402,0.009297339019232754,-0.5543007948494578,-0.5745186791895069,-0.4553008972742839,1.5693674826960398,1.6586937760640963,0.8402742865808962,0.27435692511880505,1.5188836640650665,-0.51428752530657,1.0201626829533696,-0.9877693062177954,-0.303787854117314,0.5542099181825546,2.2342011612850494,1.1964900873490003,0.02566161901174243,1.9180197862656285,0.36168996784734275,-0.9185947277776126,1.350128868152097,1.0093338760985888,0.4042351666901161,0.45984406883424556,0.5805078633245453,0.7324623353077244,2.132957634741071,2.1451816415421097,0.5409522516865753,-0.6153848387722859,0.7810014179820873,1.1358809033740525,-1.082506135737104,0.6194206088649225,1.7742210599427393 3193 Glycoprotein biosynthetic process 22 49 3.523960037834301 0.0004251483642205 Q7LGA3,O43505,Q9H4A6,Q96L58,Q8WVQ1,P35610,Q6ZXV5,Q86YN1,Q2TAA5,Q8NCH0,P46977,Q9BT22,Q8TCJ2,Q92542,Q16706,Q99805,O60476,O60502,P04843,Q9BV10,Q9HC07,Q9NQX7 Processes and pathways GO Biological process msigdb_gobp 132,262,268,272,283,410,160,171,312,70,204,342,467,211,465,343,346,215,490,111,116,127 2134,766,2033,2650,3099,262,346,215,1705,756,2424,2400,490,815,1128,410,1448,204,658,1746,1534,1681,605,511,880,465,312,160,132,1136,171,70,467,283,211,272,343,342,111,859,1045,268,116,127,1193,997,2478,747,3159 -0.39751866108604983,0.48718206135466036,-0.3409024311136362,-0.7848314137948916,-1.6613953871695926,1.4845046522176364,1.216317751801572,1.6586937760640963,-0.16014273539632354,0.5007368375870117,-0.5948794930148794,-0.5745186791895069,0.9207519138862322,0.4321969562595515,0.1838925440088085,1.05233382643295,-0.007169221259632773,1.7211740059471201,0.6322515068949177,-0.177690185818539,-0.05719278632694883,-0.14270834812699967,0.7201675789757652,0.8980485194817284,0.3759530057373177,0.9543830980982788,1.3221664240422288,1.8971479790749635,2.070521741578072,0.1838925440088085,1.8330785657592543,2.302208489423922,0.9543830980982788,1.4318115854602973,1.682361685022864,1.4583294958454196,1.2261627415331837,1.2359622824697312,2.1512615372917634,0.4042351666901161,0.2445587153188426,1.4670922847773513,2.132957634741071,2.095763221365341,0.15301100508827867,0.2891251966313216,-0.6153848387722859,0.5276212788728801,-2.326770357792346 3193 Carbohydrate derivative transport 14 16 3.5129078146069865 0.0004432312291435 O43808,P12235,Q6NUK1,Q8TDW0,Q8WTV0,Q08722,P12236,Q99808,Q9NZJ7,L0R6Q1,P07602,Q8TB61,P05141,Q9HC21 Processes and pathways GO Biological process msigdb_gobp 444,259,419,484,141,306,179,372,148,337,20,89,284,319 337,444,284,20,259,179,866,491,306,419,89,484,141,372,319,148 1.2359622824697312,0.9765264378161742,1.4228948856937176,2.762496989040066,1.5017677751833673,1.803880161059405,0.39013449402256833,0.9207519138862322,1.3408498426869389,1.0416622545332883,2.2225958317358057,0.9320183829658302,1.9991966569128934,1.1663992693165688,1.293823383957412,1.9590621281540601 3193 Membrane organization 91 223 3.508499120862839 0.0004506427237573 P50897,P98194,Q9NS69,Q16611,Q13505,Q5J8M3,Q9P2W9,O43681,P45880,P31751,Q14849,Q9NQC3,Q15363,O60499,Q15070,O75844,O75431,P17152,O43760,Q9NR31,Q15392,Q9Y5L4,Q5JRA6,Q15629,Q8NFQ8,Q12959,Q3ZCQ8,Q9P0J0,P02545,Q7Z3C6,Q9NZJ7,Q9Y4W6,Q96GC9,Q14254,Q96A33,P08183,O95202,P46459,P04083,O94901,P16615,Q14203,P30536,Q9UII2,Q9HCU5,Q9BUR5,Q8IWA4,O15027,O60313,Q12981,O95249,Q9H3K2,Q9NPA0,Q13190,P57088,P12235,Q5XKP0,P50402,Q9H4A6,Q9UQB8,Q8NHH9,P05141,Q9Y512,O14737,P49755,Q16891,Q86XL3,O75955,O15400,Q6UXV4,P46379,O15258,Q8WWC4,Q53H12,Q9NVH1,Q9BVK6,O95295,Q9UNK0,Q00765,P52789,Q86Y82,Q9BTV4,Q9NX63,O14653,Q8N1F7,O95721,O15228,Q9Y5J9,Q9Y371,Q9UH99,P61916 Processes and pathways GO Biological process msigdb_gobp 8,522,10,544,36,550,39,557,48,564,58,59,61,63,65,67,583,592,78,594,84,602,613,114,626,625,639,129,643,660,148,677,156,671,174,176,190,694,692,690,196,710,200,730,726,213,218,715,221,223,229,234,239,253,255,259,260,261,268,269,271,284,290,294,304,318,335,338,345,352,351,355,357,387,408,415,409,429,431,435,442,460,461,462,477,472,471,488,487,497,491 2301,1013,2302,1249,864,2179,916,462,294,2346,767,1331,715,2033,471,355,345,782,2905,557,78,919,221,1857,2104,63,1961,2424,903,583,1789,1047,67,338,1152,690,2651,769,190,1520,229,1647,409,2182,1521,472,643,692,1356,1676,284,1596,1522,1413,1387,176,1927,1622,2351,259,196,1623,592,2581,1177,719,2309,2678,2373,200,564,833,2832,1018,2465,866,2706,1736,48,3082,351,694,2187,1602,1603,304,2467,261,1181,8,890,1203,3161,1085,435,1109,2604,2080,2315,255,963,2163,1979,941,491,758,2358,522,431,1090,1391,1424,2499,625,223,2626,253,2265,36,1902,710,671,868,1207,820,58,893,65,1505,1288,2779,61,84,2294,1632,114,544,318,2269,639,387,550,613,1161,260,352,2913,660,968,335,442,2798,218,969,1137,477,1613,909,989,3175,626,271,2055,2333,357,1480,2938,2095,1663,1062,1839,881,174,1511,1064,156,2387,1487,2804,460,213,415,826,1881,234,268,1845,726,2875,239,59,2715,594,10,408,1148,461,148,2674,1170,129,1493,1996,39,2894,497,2478,730,2716,1699,1959,1276,429,1171,269,862,998,487,677,290,488,602,1701 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3193 Mitochondrial respiratory chain complex assembly 26 36 3.50138285842025 0.0004628503971004 Q9P0J0,Q8N183,Q9Y2R0,O95831,O75880,Q9BSH4,Q9NX14,O43676,P51970,Q9Y6M9,O95168,Q69YU5,Q9H845,O75306,Q9Y512,Q9BSK2,P47985,O43819,Q96CU9,Q15070,Q9BRT2,Q9H061,Q9Y276,Q6DKK2,O95299,O75251 Processes and pathways GO Biological process msigdb_gobp 129,641,4,389,395,910,530,16,656,935,404,22,931,543,290,162,679,175,60,65,712,68,862,219,847,876 2540,16,175,876,543,1557,395,404,847,389,2959,679,656,1868,65,1507,1002,22,219,641,928,1368,60,712,910,162,2242,68,931,530,1848,129,862,4,290,935 -0.6777844648834328,2.850934877568107,1.8185362415383943,0.3759530057373177,0.8402742865808962,-0.07407874008591195,1.1049253152266847,1.0629537868319574,0.4042351666901161,1.1152930343193794,-1.2051532199617174,0.6065201023101452,0.6322515068949177,-0.24903411518852805,2.3406400045953175,-0.04041324981336907,0.27435692511880505,2.745828206525584,1.6427531946624607,0.6577068359941382,0.3329162614491058,0.04192461851956566,2.356841664788679,0.5673949130081869,0.34734463722339803,1.8971479790749635,-0.4553008972742839,2.329750012077,0.3329162614491058,0.8751148153965543,-0.23102262249362931,2.0831876730587275,0.4042351666901161,3.129385678191442,1.4049437781239236,0.3329162614491058 3193 Glycosphingolipid metabolism 9 17 3.5008210182130544 0.0004638272383623 P10619,P06865,Q16880,Q13510,P17900,P16278,Q9NZJ7,P04062,P07602 Processes and pathways Reactome Pathways msigdb_reactome 98,224,140,45,79,82,148,53,20 666,557,53,244,224,20,584,98,1258,82,79,45,140,1432,1026,753,148 0.6194206088649225,0.8048943132507087,2.4355304023078563,1.5526815978228736,1.6185951277994044,2.762496989040066,0.7568588077238091,2.1872987787678158,0.1059833465335269,2.2399742438327923,2.2457277457630314,2.5348046058833917,2.0123785518790727,0.009297339019232754,0.25950170179577764,0.5142163574940924,1.9590621281540601 3193 Mental deterioration 44 96 3.483474393792385 0.0004949504660225 Q8IY17,Q9BQE5,O95470,Q03164,Q96F07,Q5XKP0,P50897,Q14108,Q8WVX9,O75503,O96008,P07602,Q6PI48,Q9NZJ7,P18074,O75306,P21964,Q9NQZ5,P21912,O43681,Q13510,O43819,P54098,Q96RL7,P04062,P00403,Q9UHD9,Q9UBB4,Q14203,P07686,P17900,Q9NPL8,P16278,P35637,Q9Y487,O43464,P10644,O60313,P06865,P05067,Q10713,P61916,O76024,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 640,1,128,256,648,260,8,9,524,139,525,20,533,148,653,543,288,163,553,557,45,175,686,178,53,195,325,590,710,584,79,727,82,597,88,716,604,221,224,360,236,491,247,126 1249,2033,2905,716,557,175,221,1706,2348,543,139,247,769,128,525,195,53,2879,1791,360,224,20,584,1708,2655,2006,2579,604,1258,82,2989,79,653,719,553,288,1225,2372,1795,1447,597,962,2998,1034,1081,1108,2523,8,3096,2217,686,126,1088,2584,491,2405,2589,256,2319,3025,1423,2836,236,2747,2626,45,9,710,2749,967,260,2384,533,2120,640,1269,524,2125,648,949,178,841,3151,2362,2839,1,2242,727,163,2277,148,590,2066,325,2877,88 0.1059833465335269,-0.3409024311136362,-1.1066521830470757,0.5542099181825546,0.8048943132507087,1.8185362415383943,1.6266810625618235,-0.16014273539632354,-0.5342242617338631,0.8402742865808962,2.0123785518790727,1.5358542924197818,0.48718206135466036,2.0894866813375814,0.8751148153965543,1.751667447018552,2.4355304023078563,-1.0585470825916556,-0.213128942203161,1.1865067348823226,1.6185951277994044,2.762496989040066,0.7568588077238091,-0.16014273539632354,-0.7848314137948916,-0.32228307221127694,-0.6988844633124501,0.7201675789757652,0.1059833465335269,2.2399742438327923,-1.2811099242588615,2.2457277457630314,0.6322515068949177,0.5542099181825546,0.8167483885125356,1.4049437781239236,0.12175448251162654,-0.5543007948494578,-0.213128942203161,-0.007169221259632773,0.7324623353077244,0.30380731745916084,-1.3068387009445777,0.2445587153188426,0.21440615544338357,0.19919490676105286,-0.656835659642823,3.0232917146470886,-1.6327200595968123,-0.4553008972742839,0.5935493889180543,2.095763221365341,0.21440615544338357,-0.6988844633124501,0.9207519138862322,-0.5745186791895069,-0.6988844633124501,1.510343999684222,-0.51428752530657,-1.3589269339837995,0.009297339019232754,-0.9877693062177954,1.5859138151123813,-0.8733409382481655,-0.7415449896710221,2.5348046058833917,3.0232917146470886,0.5673949130081869,-0.8733409382481655,0.30380731745916084,1.5017677751833673,-0.5543007948494578,0.863560440465855,-0.3785188752723304,0.6577068359941382,0.1059833465335269,0.8866106862369233,-0.3785188752723304,0.6450133877649504,0.3184040786732402,1.8112225085127378,0.4182557487269513,-2.2236327840032746,-0.5342242617338631,-0.9877693062177954,3.268320628293502,-0.4553008972742839,0.5542099181825546,1.8971479790749635,-0.4748273403029004,1.9590621281540601,0.7568588077238091,-0.3409024311136362,1.284289708677259,-1.0347727466327314,2.2284083926639537 3193 Corneal opacity 22 52 3.448292076957101 0.0005641436304568 P40855,P52732,O75381,O43505,Q9UBM7,Q9NX14,Q9NVI7,Q6NUK1,Q13510,P04062,Q9Y4P3,P53701,O95202,O75844,P51648,P16278,Q15645,P10619,Q06136,O75845,P06280,O96028 Drugs and Diseases Human Phenotype Ontology msigdb_hp 386,509,263,262,400,530,277,419,45,53,183,317,190,67,71,82,339,98,110,238,244,382 765,2303,1892,262,1252,2975,2001,3029,263,67,238,2074,190,382,643,53,591,244,1650,98,82,1966,653,1224,2705,2603,386,2582,71,509,317,1088,2375,2318,1391,110,1092,2606,45,1771,339,2728,532,419,3027,277,530,400,2067,1850,183,1821 0.48718206135466036,-0.51428752530657,-0.2671646500903092,1.4845046522176364,0.1059833465335269,-1.2555878176142559,-0.32228307221127694,-1.3852918433246575,1.4845046522176364,2.329750012077,1.5776579775269348,-0.3596472519831671,1.7667329517528663,1.1358809033740525,0.6450133877649504,2.4355304023078563,0.7446925671515504,1.5526815978228736,-0.12538587769838372,2.1872987787678158,2.2399742438327923,-0.303787854117314,0.6322515068949177,0.12175448251162654,-0.8287583635800084,-0.7201373856155233,1.125611440557737,-0.6988844633124501,2.2966451596705606,0.8980485194817284,1.3033138565109923,0.21440615544338357,-0.5543007948494578,-0.51428752530657,0.02566161901174243,2.1512615372917634,0.21440615544338357,-0.7201373856155233,2.5348046058833917,-0.1953518618147444,1.2359622824697312,-0.8509667351664257,0.863560440465855,1.0416622545332883,-1.3589269339837995,1.4495286247621895,0.8751148153965543,1.0840404415884148,-0.3409024311136362,-0.23102262249362931,1.7965090219596693,-0.213128942203161 3193 golgi 24 63 3.4379520691156773 0.0005861314381865 Q9UM00,P61019,Q9H0U4,P61026,P49755,Q9UI14,Q15904,Q9NR31,O15126,O14653,Q8TAD4,Q9Y487,Q15907,Q8IZA0,Q9NTJ5,O15258,Q9Y371,Q5VW38,Q969E2,O15127,Q9UBF8,Q8IXU6,Q9Y3E0,Q13190 Localization OpenCell Localization opencell_localization 385,520,664,430,304,452,323,594,463,462,86,88,216,93,486,355,487,101,358,106,496,246,250,253 2486,462,2346,1331,463,106,355,2105,2651,1647,1677,2213,1154,2309,1156,962,1033,304,2111,2638,2659,2604,2080,2315,520,430,1390,758,2589,1391,253,1752,2294,1632,323,216,101,2504,660,246,93,1613,1583,86,734,1480,358,971,664,930,932,594,486,1493,2101,496,452,385,487,250,1888,88,1220 -0.6360363435663436,0.9543830980982788,-0.5342242617338631,0.05808732403364699,0.9543830980982788,2.163357703140536,1.1964900873490003,-0.3785188752723304,-0.7848314137948916,-0.12538587769838372,-0.14270834812699967,-0.4553008972742839,0.1684982022009186,-0.51428752530657,0.1684982022009186,0.30380731745916084,0.2445587153188426,1.3408498426869389,-0.3785188752723304,-0.7631090610942425,-0.7848314137948916,-0.7201373856155233,-0.3596472519831671,-0.51428752530657,0.8866106862369233,1.0093338760985888,0.02566161901174243,0.5007368375870117,-0.6988844633124501,0.02566161901174243,1.5188836640650665,-0.177690185818539,-0.494489054305589,-0.1081741936250891,1.284289708677259,1.6586937760640963,2.181344630255124,-0.6360363435663436,0.6322515068949177,1.5442857407745552,2.205038320950641,-0.09107218097239303,-0.07407874008591195,2.2342011612850494,0.5409522516865753,-0.023739075165896593,1.1964900873490003,0.30380731745916084,0.6322515068949177,0.3329162614491058,0.3329162614491058,0.7446925671515504,0.9320183829658302,-0.023739075165896593,-0.3596472519831671,0.9207519138862322,0.9765264378161742,1.1358809033740525,0.9320183829658302,1.5358542924197818,-0.24903411518852805,2.2284083926639537,0.1374300649717309 3193 Glycosidase 12 18 3.428283246035414 0.0006074113625367 Q9BTY2,Q13724,P06865,P07686,O60476,P10253,P16278,Q16706,P06280,P04062,O60502,P54802 Functions Protein Atlas Molecular function protein_atlas_molecular_function 257,511,224,584,346,145,82,465,244,53,215,126 765,902,346,215,53,591,244,224,584,145,82,1260,126,1832,511,1429,465,257 0.48718206135466036,0.34734463722339803,1.216317751801572,1.6586937760640963,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,0.7568588077238091,1.9658133945446885,2.2399742438327923,0.1059833465335269,2.095763221365341,-0.23102262249362931,0.8980485194817284,0.009297339019232754,0.9543830980982788,1.510343999684222 3193 Ceramide metabolic process 11 17 3.427257260860875 0.0006097111420153 O95470,Q8NCC3,P06865,Q16880,Q13510,P17900,P06280,P04062,Q96G23,Q99805,O15269 Processes and pathways GO Biological process msigdb_gobp 128,193,224,140,45,79,244,53,118,343,252 252,1198,716,128,53,244,224,584,79,938,45,140,387,193,118,343,753 1.5188836640650665,0.1374300649717309,0.5542099181825546,2.0894866813375814,2.4355304023078563,1.5526815978228736,1.6185951277994044,0.7568588077238091,2.2457277457630314,0.3184040786732402,2.5348046058833917,2.0123785518790727,1.125611440557737,1.7592151429408447,2.1268132851345656,1.2261627415331837,0.5142163574940924 3193 Slc mediated transmembrane transport 16 21 3.4005458099947443 0.0006725146636743 P35613,P08195,P12235,Q70HW3,P55011,Q9H936,Q15043,P12236,Q99808,Q8TAD4,P53985,Q15758,Q8TB61,P05141,Q9Y6M7,Q9UBX3 Processes and pathways Reactome Pathways msigdb_reactome 192,417,259,77,558,593,241,179,372,86,407,565,89,284,189,57 284,417,612,259,179,3091,192,2038,407,558,241,565,1209,77,86,89,372,705,593,57,189 1.4228948856937176,1.0416622545332883,0.7078077588474234,1.5017677751833673,1.803880161059405,-1.6042899045333228,1.7592151429408447,-0.3409024311136362,1.0629537868319574,0.8048943132507087,1.5693674826960398,0.7929788244184839,0.1374300649717309,2.2514617717609795,2.2342011612850494,2.2225958317358057,1.1663992693165688,0.5805078633245453,0.7446925671515504,2.39928112695771,1.7742210599427393 3193 Organic acid transmembrane transporter activity 15 20 3.392092595215794 0.0006936099590109 O75746,P08195,Q96NB2,Q9BQT8,Q9H2D1,Q02978,Q9UJS0,Q9Y619,Q15758,P08183,Q9H936,Q9H9B4,P53985,P53007,Q9UBX3 Functions GO Molecular function msigdb_gomf 350,417,546,197,7,644,169,267,565,176,593,601,407,440,57 2346,350,176,417,833,866,440,407,644,565,1209,546,197,7,705,593,601,57,169,267 -0.5342242617338631,1.2064269794639189,1.8112225085127378,1.0416622545332883,0.4182557487269513,0.39013449402256833,0.9875161701203701,1.0629537868319574,0.6450133877649504,0.7929788244184839,0.1374300649717309,0.8402742865808962,1.751667447018552,3.043830354362099,0.5805078633245453,0.7446925671515504,0.7324623353077244,2.39928112695771,1.854681789652418,1.4758172511688186 3193 Glycoprotein metabolic process 33 56 3.389521078508152 0.0007001482590558 Q13724,Q7LGA3,O43505,O14734,P61803,Q9H0U4,Q9H4A6,O00754,Q96L58,Q8WVQ1,P35610,Q6ZXV5,Q86YN1,Q2TAA5,P04844,Q8NCH0,P46977,Q9BT22,Q9H0U3,Q92542,Q16706,Q8TCJ2,Q99805,O60502,O60476,Q10471,Q9Y5P6,P04843,Q9BV10,Q9HC07,P62820,O60762,Q9NQX7 Processes and pathways GO Biological process msigdb_gobp 511,132,262,766,658,664,268,765,272,283,410,160,171,312,815,70,204,342,859,211,465,467,343,215,346,605,747,490,111,116,758,756,127 2134,765,766,2033,2650,3099,262,346,215,1705,756,2424,2400,490,815,1256,1128,410,1448,204,658,758,1746,1534,1681,605,511,880,1429,465,312,160,132,1136,171,70,467,283,211,272,3151,343,858,342,111,859,664,1045,268,116,127,1193,997,2478,747,3159 -0.39751866108604983,0.48718206135466036,0.48718206135466036,-0.3409024311136362,-0.7848314137948916,-1.6613953871695926,1.4845046522176364,1.216317751801572,1.6586937760640963,-0.16014273539632354,0.5007368375870117,-0.5948794930148794,-0.5745186791895069,0.9207519138862322,0.4321969562595515,0.1059833465335269,0.1838925440088085,1.05233382643295,-0.007169221259632773,1.7211740059471201,0.6322515068949177,0.5007368375870117,-0.177690185818539,-0.05719278632694883,-0.14270834812699967,0.7201675789757652,0.8980485194817284,0.3759530057373177,0.009297339019232754,0.9543830980982788,1.3221664240422288,1.8971479790749635,2.070521741578072,0.1838925440088085,1.8330785657592543,2.302208489423922,0.9543830980982788,1.4318115854602973,1.682361685022864,1.4583294958454196,-2.2236327840032746,1.2261627415331837,0.4042351666901161,1.2359622824697312,2.1512615372917634,0.4042351666901161,0.6322515068949177,0.2445587153188426,1.4670922847773513,2.132957634741071,2.095763221365341,0.15301100508827867,0.2891251966313216,-0.6153848387722859,0.5276212788728801,-2.326770357792346 3193 Golgi vesicle transport 49 136 3.385846411154397 0.0007095908636809 P24390,P61019,P98194,Q9H4A6,Q9H0U4,Q8NHH9,O43731,Q9BVK6,Q9P2W9,Q8TBA6,P61026,Q96RL7,P49755,Q96PC5,Q15363,Q12907,O60499,P46459,P49257,Q8N2H4,Q12893,P51572,O60826,Q9HCU5,P11279,Q9NR31,O15126,O14653,O15027,Q8WVM8,Q9Y3B3,Q9HD47,Q12981,O14828,O15258,Q4J6C6,O95249,Q6NUQ1,Q5JRA6,O15127,Q8IWJ2,Q9Y3A6,Q9UPN3,O95782,O15260,Q9Y282,P62820,Q96A65,Q13190 Processes and pathways GO Biological process msigdb_gobp 2,520,522,268,664,271,26,415,39,688,430,178,304,180,61,574,63,694,447,69,456,327,582,726,206,594,463,462,715,734,95,735,223,470,355,505,229,483,613,106,761,498,622,749,245,119,758,636,253 844,2301,1280,2179,2486,916,462,470,1331,715,463,106,355,245,782,2542,2250,26,2366,1221,2104,63,957,1961,582,2424,903,2827,1468,2651,229,1647,2182,1521,1048,749,206,2213,2,1156,2549,1033,2744,1654,1081,694,1053,1602,447,304,1181,1203,327,1085,2962,2659,2604,2080,2584,2315,2660,2376,1979,520,430,1055,1390,758,3119,1746,1057,522,1090,456,574,2499,223,253,1537,1902,2779,61,2294,1632,505,613,483,2504,1235,823,761,1345,69,1991,1613,271,1005,688,871,947,734,1480,1663,1839,636,1483,777,180,178,1487,415,664,268,1845,2061,726,1147,735,594,1493,1996,39,2101,2894,1997,1070,1672,622,119,1673,2030,498,95,1102,1220,1854 0.4042351666901161,-0.51428752530657,0.09011573382996567,-0.43590826117893794,-0.6360363435663436,0.3329162614491058,0.9543830980982788,0.9432286304255554,0.05808732403364699,0.5542099181825546,0.9543830980982788,2.163357703140536,1.1964900873490003,1.5442857407745552,0.4735513630461408,-0.6777844648834328,-0.4748273403029004,2.6816050945494077,-0.5543007948494578,0.12175448251162654,-0.3785188752723304,2.346058243177083,0.30380731745916084,-0.303787854117314,0.7568588077238091,-0.5948794930148794,0.34734463722339803,-0.9877693062177954,-0.023739075165896593,-0.7848314137948916,1.6104756568747511,-0.12538587769838372,-0.43590826117893794,-0.05719278632694883,0.22952714396117282,0.5142163574940924,1.7057429944746445,-0.4553008972742839,3.21572160468917,0.1684982022009186,-0.6777844648834328,0.2445587153188426,-0.8733409382481655,-0.12538587769838372,0.21440615544338357,0.5805078633245453,0.22952714396117282,-0.09107218097239303,0.9765264378161742,1.3408498426869389,0.15301100508827867,0.1374300649717309,1.2650915011001496,0.21440615544338357,-1.2051532199617174,-0.7848314137948916,-0.7201373856155233,-0.3596472519831671,-0.6988844633124501,-0.51428752530657,-0.7848314137948916,-0.5543007948494578,-0.303787854117314,0.8866106862369233,1.0093338760985888,0.22952714396117282,0.02566161901174243,0.5007368375870117,-1.8085693165877301,-0.177690185818539,0.22952714396117282,0.8866106862369233,0.21440615544338357,0.9654822230844401,0.7810014179820873,-0.6360363435663436,1.6266810625618235,1.5188836640650665,-0.05719278632694883,-0.2671646500903092,-0.9185947277776126,2.3514587661376916,-0.494489054305589,-0.1081741936250891,0.9094287765563077,0.7078077588474234,0.9320183829658302,-0.6360363435663436,0.12175448251162654,0.4321969562595515,0.5007368375870117,0.05808732403364699,2.31327983578579,-0.303787854117314,-0.09107218097239303,1.4583294958454196,0.27435692511880505,0.5935493889180543,0.39013449402256833,0.3184040786732402,0.5409522516865753,-0.023739075165896593,-0.12538587769838372,-0.23102262249362931,0.6703324293561015,-0.023739075165896593,0.48718206135466036,1.803880161059405,1.8112225085127378,-0.023739075165896593,1.05233382643295,0.6322515068949177,1.4670922847773513,-0.23102262249362931,-0.3409024311136362,0.5542099181825546,0.1838925440088085,0.5409522516865753,0.7446925671515504,-0.023739075165896593,-0.303787854117314,2.572831939044648,-0.3596472519831671,-1.0585470825916556,-0.303787854117314,0.22952714396117282,-0.12538587769838372,0.6953823294342337,2.1268132851345656,-0.12538587769838372,-0.32228307221127694,0.9207519138862322,2.1991455126433834,0.21440615544338357,0.1374300649717309,-0.23102262249362931 3193 Exocytic vesicle 19 41 3.37380913740186 0.0007413575119687 P50897,Q7L0J3,Q9BVK6,O95295,P20020,Q9GZY8,P61026,Q86Y82,Q9UI14,O60499,Q9BT78,P11279,O43760,Q92542,O15400,Q15907,P05067,O76024,Q96A57 Localization GO Cellular component msigdb_gocc 8,149,415,409,291,299,430,442,452,63,459,206,78,211,345,216,360,247,121 1249,2031,463,345,78,63,247,409,360,1677,206,291,1679,3117,8,890,1203,3161,1979,1130,430,1361,1424,2265,3077,907,771,2779,216,789,149,442,211,2095,1722,121,459,415,299,452,1673 0.1059833465335269,-0.3409024311136362,0.9543830980982788,1.216317751801572,2.2457277457630314,2.346058243177083,1.5358542924197818,1.05233382643295,1.1865067348823226,-0.14270834812699967,1.7057429944746445,1.3959088234962316,-0.14270834812699967,-1.778616500027411,3.0232917146470886,0.36168996784734275,0.1374300649717309,-2.3972018839891502,-0.303787854117314,0.1838925440088085,1.0093338760985888,0.04192461851956566,0.009297339019232754,-0.4748273403029004,-1.5204378296208023,0.34734463722339803,0.48718206135466036,-0.9185947277776126,1.6586937760640963,0.4735513630461408,1.952285648216789,0.9875161701203701,1.682361685022864,-0.3596472519831671,-0.16014273539632354,2.1206472108366774,0.9654822230844401,1.05233382643295,1.38683389940539,0.9765264378161742,-0.12538587769838372 3193 Lipid binding 34 134 3.362437568857775 0.0007725759365619 Q9BQE5,O00264,Q99623,Q13432,P50897,Q14108,Q13045,Q9H4A6,Q8WTV0,P07602,Q9NZJ7,P28070,O14773,P38435,P35610,Q9NQZ5,Q15067,P45880,P21796,P04062,O15173,Q14849,Q8NCC3,P30536,Q99584,Q92643,Q9BWH2,O60313,O60443,Q9Y371,Q9H490,P05023,Q9Y5X3,A6NIH7 Functions GO Molecular function msigdb_gomf 1,258,388,134,8,9,391,268,141,20,148,405,150,157,410,163,420,48,51,53,56,58,193,200,336,468,479,221,96,487,366,363,373,120 666,120,258,1440,1249,864,150,767,1786,2033,56,2650,1221,221,96,2104,957,623,2002,563,572,1962,1015,2702,887,53,692,363,1522,20,2847,1387,1200,959,1860,2458,2351,1792,669,3134,1445,51,2309,1931,2928,405,3021,2311,200,2947,410,1179,157,48,2681,1566,1602,8,1528,3000,2111,2638,2584,2375,963,491,2408,2043,1090,1768,391,134,2265,1749,1537,9,1752,58,2323,1903,420,1505,771,2971,1987,1542,2439,2440,773,2798,1345,1991,193,855,141,1480,468,1880,1992,2768,1511,2335,2769,336,388,883,3059,2914,1,1026,2805,479,826,1324,627,366,268,2338,163,1587,2449,148,1996,1672,577,830,1276,978,1171,487,2517,1465,1701,373 0.6194206088649225,2.1206472108366774,1.5017677751833673,-0.007169221259632773,0.1059833465335269,0.39013449402256833,1.945483805688231,0.48718206135466036,-0.213128942203161,-0.3409024311136362,2.39928112695771,-0.7848314137948916,0.12175448251162654,1.6266810625618235,2.1932323689347277,-0.3785188752723304,0.30380731745916084,0.682890738977402,-0.32228307221127694,0.7929788244184839,0.7810014179820873,-0.303787854117314,0.25950170179577764,-0.8287583635800084,0.36168996784734275,2.4355304023078563,0.5805078633245453,1.176476578042439,-0.05719278632694883,2.762496989040066,-1.011180888611287,0.02566161901174243,0.1374300649717309,0.30380731745916084,-0.24903411518852805,-0.6153848387722859,-0.5342242617338631,-0.213128942203161,0.6194206088649225,-1.9940123659347255,-0.007169221259632773,2.5007588066882245,-0.51428752530657,-0.28541547461577405,-1.1555145615983378,1.0629537868319574,-1.3589269339837995,-0.51428752530657,1.7364816398521126,-1.180235642836601,1.05233382643295,0.15301100508827867,1.9041316359550924,2.515439795372476,-0.8067138905481915,-0.07407874008591195,-0.09107218097239303,3.0232917146470886,-0.05719278632694883,-1.3068387009445777,-0.3785188752723304,-0.7631090610942425,-0.6988844633124501,-0.5543007948494578,0.30380731745916084,0.9207519138862322,-0.5745186791895069,-0.3409024311136362,0.21440615544338357,-0.1953518618147444,1.1152930343193794,2.0577643966472143,-0.4748273403029004,-0.177690185818539,-0.05719278632694883,3.0232917146470886,-0.177690185818539,2.394036011434074,-0.51428752530657,-0.2671646500903092,1.03093867386121,-0.04041324981336907,0.48718206135466036,-1.230269771179215,-0.303787854117314,-0.05719278632694883,-0.5948794930148794,-0.5948794930148794,0.48718206135466036,-0.9414783391764264,0.05808732403364699,-0.303787854117314,1.7592151429408447,0.4042351666901161,1.9991966569128934,-0.023739075165896593,0.9543830980982788,-0.24903411518852805,-0.303787854117314,-0.8958829370602809,-0.04041324981336907,-0.51428752530657,-0.8958829370602809,1.2457167051043052,1.125611440557737,0.3759530057373177,-1.4657034897922236,-1.1066521830470757,3.268320628293502,0.25950170179577764,-0.9414783391764264,0.9432286304255554,0.4321969562595515,0.07415070895816572,0.682890738977402,1.176476578042439,1.4670922847773513,-0.51428752530657,1.8971479790749635,-0.07407874008591195,-0.5948794930148794,1.9590621281540601,-0.303787854117314,-0.12538587769838372,0.7810014179820873,0.4321969562595515,0.1059833465335269,0.30380731745916084,0.1684982022009186,0.9320183829658302,-0.6360363435663436,-0.007169221259632773,-0.14270834812699967,1.1663992693165688 3193 Abnormal circulating lipid concentration 40 79 3.353251105856515 0.0007986821081809 O95470,P40855,Q15125,P50402,O75381,Q13045,P02545,O75880,Q9UBM7,P38571,Q9NVI7,P07602,Q9NZJ7,P28070,Q8N511,P23786,Q03252,Q9UJS0,P31751,Q9Y4P3,Q8WXH0,O43772,P49257,O75844,Q15904,P49748,O75648,Q9BTV4,O75431,Q14739,Q15392,P22830,Q10471,P37268,Q15800,Q9BV10,O75845,P61916,P06280,P40939 Drugs and Diseases Human Phenotype Ontology msigdb_hp 128,386,131,261,263,391,643,395,400,526,277,20,148,405,161,167,680,169,564,183,575,191,447,67,323,455,330,460,583,210,84,596,605,99,107,111,238,491,244,631 2303,3099,1076,191,263,583,330,67,238,395,128,643,244,1649,20,796,3138,596,167,405,1600,564,2705,2603,1260,3031,99,526,386,631,1081,2884,447,455,261,923,3096,850,2292,2218,2375,1308,491,2318,1391,680,2436,605,391,3050,2412,210,1771,131,84,788,107,323,687,1987,3186,1776,161,2874,575,1839,1401,460,111,931,2061,277,148,400,2067,169,911,183,754 -0.51428752530657,-1.6613953871695926,0.21440615544338357,1.7592151429408447,1.4845046522176364,0.7568588077238091,1.2457167051043052,2.329750012077,1.5776579775269348,1.1049253152266847,2.0894866813375814,0.6450133877649504,1.5526815978228736,-0.12538587769838372,2.762496989040066,0.45984406883424556,-2.0581032829089954,0.7324623353077244,1.8618274754931423,1.0629537868319574,-0.09107218097239303,0.7929788244184839,-0.8287583635800084,-0.7201373856155233,0.1059833465335269,-1.3852918433246575,2.1872987787678158,0.8751148153965543,1.125611440557737,0.6703324293561015,0.21440615544338357,-1.0585470825916556,0.9765264378161742,0.9654822230844401,1.4931547427369818,0.3329162614491058,-1.6327200595968123,0.4042351666901161,-0.494489054305589,-0.4553008972742839,-0.5543007948494578,0.07415070895816572,0.9207519138862322,-0.51428752530657,0.02566161901174243,0.6065201023101452,-0.5948794930148794,0.7201675789757652,1.1152930343193794,-1.4386772460322241,-0.5745186791895069,1.6979807301199143,-0.1953518618147444,2.070521741578072,2.2399742438327923,0.4735513630461408,2.163357703140536,1.284289708677259,0.5935493889180543,-0.303787854117314,-4.33835425185139,-0.1953518618147444,1.8971479790749635,-1.0347727466327314,0.7810014179820873,-0.23102262249362931,0.02566161901174243,0.9654822230844401,2.1512615372917634,0.3329162614491058,-0.3409024311136362,1.4495286247621895,1.9590621281540601,1.0840404415884148,-0.3409024311136362,1.854681789652418,0.34734463722339803,1.7965090219596693,0.5142163574940924 3193 Cristae formation 14 20 3.3490353258588845 0.0008109345555546 Q9Y512,Q6UXV4,Q5XKP0,Q13505,P06576,Q9NX63,O75431,O75964,P17152,P56385,P24539,Q9BUR5,Q9NVH1,Q16891 Processes and pathways Reactome Pathways msigdb_reactome 290,352,260,36,552,461,583,47,592,305,83,213,408,318 583,1281,47,552,592,83,1333,983,2465,2932,618,305,36,318,260,352,213,408,461,290 0.7568588077238091,0.09011573382996567,2.515439795372476,0.8167483885125356,0.7446925671515504,2.2399742438327923,0.05808732403364699,0.2891251966313216,-0.6153848387722859,-1.1555145615983378,0.6953823294342337,1.3408498426869389,2.596136262438205,1.293823383957412,1.5017677751833673,1.2064269794639189,1.682361685022864,1.0629537868319574,0.9654822230844401,1.4049437781239236 3193 Electron transport chain oxphos system in mitochondria 22 47 3.338592693474194 0.0008420393140746 P12235,Q9UDW1,O75880,O43676,P14406,P51970,O95168,P09669,P05141,O75306,O14949,P06576,P21912,O75964,P56385,P12236,P00403,P24539,P22695,P56134,P13073,Q7KZN9 Processes and pathways WikiPathways msigdb_wp 259,6,395,16,18,656,404,652,284,543,37,552,553,47,305,179,195,83,97,618,109,112 2540,832,37,16,876,543,958,1557,395,1281,47,404,1963,847,195,284,552,652,1153,259,179,109,18,770,922,3040,981,553,97,83,1333,2959,1795,1284,983,679,2932,3049,656,618,305,1507,1002,112,6,730,935 -0.6777844648834328,0.4182557487269513,2.58685650649295,2.850934877568107,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.1049253152266847,0.09011573382996567,2.515439795372476,1.0629537868319574,-0.303787854117314,0.4042351666901161,1.751667447018552,1.4228948856937176,0.8167483885125356,0.6322515068949177,0.1684982022009186,1.5017677751833673,1.803880161059405,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,-1.4118743308181245,0.2891251966313216,0.8167483885125356,2.1932323689347277,2.2399742438327923,0.05808732403364699,-1.2051532199617174,-0.213128942203161,0.09011573382996567,0.2891251966313216,0.6065201023101452,-1.1555145615983378,-1.4386772460322241,0.6322515068949177,0.6953823294342337,1.3408498426869389,-0.04041324981336907,0.27435692511880505,2.1451816415421097,3.1003852237037637,0.5542099181825546,0.3329162614491058 3193 Abnormal circulating cholesterol concentration 22 37 3.307975785468894 0.0009397293455641 Q15125,P50402,Q13045,Q9UBM7,P38571,Q9NVI7,P07602,Q9NZJ7,Q8N511,Q9UJS0,Q8WXH0,Q15904,Q9BTV4,O75431,Q14739,Q15392,Q10471,P37268,Q15800,O75845,Q9BV10,P61916 Drugs and Diseases Human Phenotype Ontology msigdb_hp 131,261,391,400,526,277,20,148,161,169,575,323,460,583,210,84,605,99,107,238,111,491 3099,583,238,643,1649,20,2705,99,526,1081,2884,261,3096,1308,491,1391,605,391,2412,210,131,84,788,107,323,1987,1776,161,2874,575,460,111,2061,277,148,400,169 -1.6613953871695926,0.7568588077238091,1.5776579775269348,0.6450133877649504,-0.12538587769838372,2.762496989040066,-0.8287583635800084,2.1872987787678158,0.8751148153965543,0.21440615544338357,-1.0585470825916556,1.4931547427369818,-1.6327200595968123,0.07415070895816572,0.9207519138862322,0.02566161901174243,0.7201675789757652,1.1152930343193794,-0.5745186791895069,1.6979807301199143,2.070521741578072,2.2399742438327923,0.4735513630461408,2.163357703140536,1.284289708677259,-0.303787854117314,-0.1953518618147444,1.8971479790749635,-1.0347727466327314,0.7810014179820873,0.9654822230844401,2.1512615372917634,-0.3409024311136362,1.4495286247621895,1.9590621281540601,1.0840404415884148,1.854681789652418 3193 Hydrolase activity hydrolyzing o glycosyl compounds 13 19 3.2786040548183037 0.0010432189553233 Q9BTY2,Q13724,P06865,O60502,P07686,P17900,P10253,P16278,Q16706,P06280,P04062,O60476,P54802 Functions GO Molecular function msigdb_gomf 257,511,224,215,584,79,145,82,465,244,53,346,126 765,346,215,53,591,244,224,584,145,82,79,1260,126,511,1429,465,3083,257,746 0.48718206135466036,1.216317751801572,1.6586937760640963,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,0.7568588077238091,1.9658133945446885,2.2399742438327923,2.2457277457630314,0.1059833465335269,2.095763221365341,0.8980485194817284,0.009297339019232754,0.9543830980982788,-1.5481519943674076,1.510343999684222,0.5276212788728801 3193 Proton transmembrane transporter activity 13 34 3.2700688997717084 0.0010752129197233 P12235,P00403,Q9UDW1,Q13423,P13073,Q96ES6,O75964,Q93050,Q7KZN9,P24539,Q9Y487,P05141,O95202 Functions GO Molecular function msigdb_gomf 259,195,6,43,109,142,47,208,112,83,88,284,190 1281,47,190,195,284,552,668,1153,259,109,981,693,2547,83,1333,1284,983,962,2998,679,2932,3161,618,305,1361,554,43,112,208,142,593,6,2151,88 0.09011573382996567,2.515439795372476,1.7667329517528663,1.751667447018552,1.4228948856937176,0.8167483885125356,0.6194206088649225,0.1684982022009186,1.5017677751833673,2.1512615372917634,0.2891251966313216,0.5805078633245453,-0.6777844648834328,2.2399742438327923,0.05808732403364699,0.09011573382996567,0.2891251966313216,0.30380731745916084,-1.3068387009445777,0.6065201023101452,-1.1555145615983378,-2.3972018839891502,0.6953823294342337,1.3408498426869389,0.04192461851956566,0.8167483885125356,2.5443983795118403,2.1451816415421097,1.7057429944746445,1.992569263975948,0.7446925671515504,3.1003852237037637,-0.39751866108604983,2.2284083926639537 3193 Tetrapyrrole binding 9 16 3.2688365982609096 0.0010799064614748 P30519,O00264,Q16850,Q6UW02,Q7KZN9,P09601,O15173,O43169,P53701 Functions GO Molecular function msigdb_gomf 32,258,170,74,112,17,56,25,317 258,56,25,668,17,1127,32,317,170,74,112,990,1143,1144,393,2536 1.5017677751833673,2.39928112695771,2.6859731952221364,0.6194206088649225,2.850934877568107,0.1838925440088085,2.637217657100284,1.3033138565109923,1.8475085220023033,2.2685480296028047,2.1451816415421097,0.2891251966313216,0.1838925440088085,0.1838925440088085,1.1152930343193794,-0.656835659642823 3193 Clumsiness 11 22 3.2677736261884345 0.0010839702840657 Q15067,O75503,Q13510,O43819,Q9NR77,O00165,Q9NZJ7,Q6PI48,P07602,O14773,Q05086 Drugs and Diseases Human Phenotype Ontology msigdb_hp 420,139,45,175,49,303,148,533,20,150,503 303,765,150,2303,557,175,139,1305,20,1258,1795,1447,1081,503,45,420,2796,533,841,49,148,2066 1.3408498426869389,0.48718206135466036,1.945483805688231,-0.51428752530657,0.8048943132507087,1.8185362415383943,2.0123785518790727,0.07415070895816572,2.762496989040066,0.1059833465335269,-0.213128942203161,-0.007169221259632773,0.21440615544338357,0.9094287765563077,2.5348046058833917,1.03093867386121,-0.9414783391764264,0.863560440465855,0.4182557487269513,2.515439795372476,1.9590621281540601,-0.3409024311136362 3193 Sphingolipid biosynthetic process 9 14 3.2662683122057463 0.0010897494151265 O95470,Q16880,Q9P035,Q13510,Q06136,P04062,Q96G23,Q99805,O15269 Processes and pathways GO Biological process msigdb_gobp 128,140,203,45,110,53,118,343,252 252,1198,128,53,2309,110,45,140,387,118,343,753,203,1493 1.5188836640650665,0.1374300649717309,2.0894866813375814,2.4355304023078563,-0.51428752530657,2.1512615372917634,2.5348046058833917,2.0123785518790727,1.125611440557737,2.1268132851345656,1.2261627415331837,0.5142163574940924,1.7288431475403072,-0.023739075165896593 3193 Dementia 26 58 3.2606977089655778 0.0011113845600783 Q8IY17,Q14108,Q8WVX9,O96008,P07602,Q9NZJ7,Q9NQZ5,P21912,O43681,Q13510,P54098,Q96RL7,P04062,P00403,Q9UHD9,Q9UBB4,Q14203,P17900,P35637,Q9Y487,O43464,O60313,P06865,P05067,P61916,O76024 Drugs and Diseases Human Phenotype Ontology msigdb_hp 640,9,524,525,20,148,163,553,557,45,686,178,53,195,325,590,710,79,597,88,716,221,224,360,491,247 1249,2033,2905,716,557,221,2348,247,525,195,53,2879,1791,360,224,20,2006,2579,1258,79,719,553,1225,2372,1795,1447,597,962,2998,1081,1108,2217,686,1088,2584,491,2319,1423,2626,45,9,710,967,2120,640,1269,524,2125,949,178,841,3151,2362,163,148,590,325,88 0.1059833465335269,-0.3409024311136362,-1.1066521830470757,0.5542099181825546,0.8048943132507087,1.6266810625618235,-0.5342242617338631,1.5358542924197818,0.8751148153965543,1.751667447018552,2.4355304023078563,-1.0585470825916556,-0.213128942203161,1.1865067348823226,1.6185951277994044,2.762496989040066,-0.32228307221127694,-0.6988844633124501,0.1059833465335269,2.2457277457630314,0.5542099181825546,0.8167483885125356,0.12175448251162654,-0.5543007948494578,-0.213128942203161,-0.007169221259632773,0.7324623353077244,0.30380731745916084,-1.3068387009445777,0.21440615544338357,0.19919490676105286,-0.4553008972742839,0.5935493889180543,0.21440615544338357,-0.6988844633124501,0.9207519138862322,-0.51428752530657,0.009297339019232754,-0.7415449896710221,2.5348046058833917,3.0232917146470886,0.5673949130081869,0.30380731745916084,-0.3785188752723304,0.6577068359941382,0.1059833465335269,0.8866106862369233,-0.3785188752723304,0.3184040786732402,1.8112225085127378,0.4182557487269513,-2.2236327840032746,-0.5342242617338631,1.8971479790749635,1.9590621281540601,0.7568588077238091,1.284289708677259,2.2284083926639537 3193 Calcium signaling pathway 8 17 3.2591021612566555 0.0011176541329043 P20020,P12235,P16615,Q9Y277,P45880,P21796,P12236,P05141 Processes and pathways KEGG Pathways msigdb_kegg 291,259,196,135,48,51,179,284 284,1596,259,179,196,1623,1501,291,51,48,321,2836,1901,1425,2381,2478,135 1.4228948856937176,-0.09107218097239303,1.5017677751833673,1.803880161059405,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,2.5007588066882245,2.515439795372476,1.284289708677259,-0.9877693062177954,-0.2671646500903092,0.009297339019232754,-0.5543007948494578,-0.6153848387722859,2.051351117777622 3193 Nucleobase containing compound transmembrane transporter activity 10 13 3.257886446237266 0.0011224531174947 Q9BSK2,P12235,Q6NUK1,Q9H2D1,P12236,Q99808,L0R6Q1,Q8TB61,P05141,Q9HC21 Functions GO Molecular function msigdb_gomf 162,259,419,7,179,372,337,89,284,319 337,444,284,259,179,866,1336,419,89,372,162,7,319 1.2359622824697312,0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,0.39013449402256833,0.05808732403364699,1.0416622545332883,2.2225958317358057,1.1663992693165688,1.8971479790749635,3.043830354362099,1.293823383957412 3193 Outer mitochondrial membrane protein complex 13 16 3.2566483875021746 0.0011273598765038 Q9Y512,Q6UXV4,Q13505,Q5XKP0,Q15388,Q9NS69,Q9NX63,Q8N4H5,O96008,Q9BUR5,Q8IWA4,Q9NVH1,Q16891 Localization GO Cellular component msigdb_gocc 290,352,36,260,232,10,461,15,525,213,218,408,318 583,1152,525,2465,36,232,318,260,352,218,15,213,10,408,461,290 0.7568588077238091,0.1684982022009186,0.8751148153965543,-0.6153848387722859,2.596136262438205,1.6023224295792171,1.293823383957412,1.5017677751833673,1.2064269794639189,1.6586937760640963,2.9120109684113684,1.682361685022864,3.0024397548003465,1.0629537868319574,0.9654822230844401,1.4049437781239236 3193 Cognitive impairment 66 164 3.251670626400034 0.0011472888970931 Q8IY17,Q9BQE5,O95470,Q03164,Q9Y2R0,Q96F07,P12235,Q5XKP0,P50897,Q14108,O75381,Q9Y619,Q8WVX9,O75503,O95831,O96008,P07602,Q6PI48,Q9NZJ7,Q96GW9,P18074,P40855,Q9Y4W6,O75306,Q9NZ08,P21964,Q9NQZ5,Q13217,Q9UJS0,P21912,O43681,Q13510,O43819,P54098,Q96RL7,Q99720,P04062,P07196,P00403,Q9UHD9,Q9UBB4,P13473,Q14203,P07686,P17900,Q9NPL8,P16278,Q9Y487,P35637,O43464,P20700,P10644,Q6DKK2,O60313,Q6PGP7,Q9Y5P6,P06865,P05067,P11166,Q10713,P61916,P06280,Q9Y263,O76024,P42345,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 640,1,128,256,4,648,259,260,8,9,263,267,524,139,389,525,20,533,148,541,653,386,677,543,159,288,163,549,169,553,557,45,175,686,178,50,53,438,195,325,590,72,710,584,79,727,82,88,597,716,719,604,219,221,217,747,224,360,612,236,491,244,508,247,500,126 1249,1786,2033,2905,716,557,175,221,1706,2348,543,263,139,247,769,128,389,525,195,1304,53,2879,1791,1356,360,244,224,438,20,584,2601,1708,2655,2006,2579,604,612,259,72,1258,82,2989,79,653,1224,719,3065,553,288,3066,1225,982,2372,1795,1447,2256,597,962,2998,386,500,1034,1081,1108,1082,2622,1084,2523,1711,8,3096,2217,850,1800,686,126,1088,2584,2375,1308,2219,941,491,2405,2589,1090,1391,256,2319,3025,1423,2836,236,2992,2747,2015,2626,549,3050,45,9,710,2607,1287,2085,2749,1632,2890,1611,967,2270,260,219,2384,217,533,2120,2912,640,1811,1269,1320,524,2125,744,648,541,949,178,841,2785,1909,3151,2362,2839,50,1,2242,2696,2420,727,1491,163,1459,2245,2277,159,148,590,2066,780,325,2537,169,2877,934,508,4,1379,88,677,747,267,1821 0.1059833465335269,-0.213128942203161,-0.3409024311136362,-1.1066521830470757,0.5542099181825546,0.8048943132507087,1.8185362415383943,1.6266810625618235,-0.16014273539632354,-0.5342242617338631,0.8402742865808962,1.4845046522176364,2.0123785518790727,1.5358542924197818,0.48718206135466036,2.0894866813375814,1.1152930343193794,0.8751148153965543,1.751667447018552,0.07415070895816572,2.4355304023078563,-1.0585470825916556,-0.213128942203161,0.04192461851956566,1.1865067348823226,1.5526815978228736,1.6185951277994044,0.9875161701203701,2.762496989040066,0.7568588077238091,-0.7201373856155233,-0.16014273539632354,-0.7848314137948916,-0.32228307221127694,-0.6988844633124501,0.7201675789757652,0.7078077588474234,1.5017677751833673,2.291063262623579,0.1059833465335269,2.2399742438327923,-1.2811099242588615,2.2457277457630314,0.6322515068949177,0.12175448251162654,0.5542099181825546,-1.492956015355766,0.8167483885125356,1.4049437781239236,-1.492956015355766,0.12175448251162654,0.2891251966313216,-0.5543007948494578,-0.213128942203161,-0.007169221259632773,-0.4748273403029004,0.7324623353077244,0.30380731745916084,-1.3068387009445777,1.125611440557737,0.9094287765563077,0.2445587153188426,0.21440615544338357,0.19919490676105286,0.21440615544338357,-0.7415449896710221,0.21440615544338357,-0.656835659642823,-0.16014273539632354,3.0232917146470886,-1.6327200595968123,-0.4553008972742839,0.4042351666901161,-0.213128942203161,0.5935493889180543,2.095763221365341,0.21440615544338357,-0.6988844633124501,-0.5543007948494578,0.07415070895816572,-0.4553008972742839,0.3184040786732402,0.9207519138862322,-0.5745186791895069,-0.6988844633124501,0.21440615544338357,0.02566161901174243,1.510343999684222,-0.51428752530657,-1.3589269339837995,0.009297339019232754,-0.9877693062177954,1.5859138151123813,-1.2811099242588615,-0.8733409382481655,-0.32228307221127694,-0.7415449896710221,0.8285415486462114,-1.4386772460322241,2.5348046058833917,3.0232917146470886,0.5673949130081869,-0.7201373856155233,0.09011573382996567,-0.3596472519831671,-0.8733409382481655,-0.1081741936250891,-1.0585470825916556,-0.09107218097239303,0.30380731745916084,-0.4748273403029004,1.5017677751833673,1.6427531946624607,-0.5543007948494578,1.6586937760640963,0.863560440465855,-0.3785188752723304,-1.1066521830470757,0.6577068359941382,-0.213128942203161,0.1059833465335269,0.07415070895816572,0.8866106862369233,-0.3785188752723304,0.5276212788728801,0.6450133877649504,0.8519470898097677,0.3184040786732402,1.8112225085127378,0.4182557487269513,-0.9185947277776126,-0.2671646500903092,-2.2236327840032746,-0.5342242617338631,-0.9877693062177954,2.5056676046326203,3.268320628293502,-0.4553008972742839,-0.8067138905481915,-0.5745186791895069,0.5542099181825546,-0.023739075165896593,1.8971479790749635,-0.007169221259632773,-0.4553008972742839,-0.4748273403029004,1.9041316359550924,1.9590621281540601,0.7568588077238091,-0.3409024311136362,0.48718206135466036,1.284289708677259,-0.656835659642823,1.854681789652418,-1.0347727466327314,0.3329162614491058,0.9094287765563077,3.129385678191442,0.04192461851956566,2.2284083926639537,0.6194206088649225,0.5276212788728801,1.4758172511688186,-0.213128942203161 3193 Cardiac muscle contraction 7 19 3.250751148489049 0.0011510055699994 P22695,P00403,P16615,O14949,Q9UDW1,P13073,P14406 Processes and pathways KEGG Pathways msigdb_kegg 97,195,196,37,6,109,18 37,195,363,1676,1305,668,652,1153,109,18,770,922,196,981,97,1284,679,798,6 2.58685650649295,1.751667447018552,1.176476578042439,-0.14270834812699967,0.07415070895816572,0.6194206088649225,0.6322515068949177,0.1684982022009186,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,1.751667447018552,0.2891251966313216,2.1932323689347277,0.09011573382996567,0.6065201023101452,0.45984406883424556,3.1003852237037637 3193 Receptor 10 28 3.247583231450841 0.0011638961716891 Q567V2,Q13432,O75381,Q14108,Q8WTV0,Q9UQB8,Q9NR77,Q9BUN8,A6NIH7,P57105 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 3,134,263,9,141,269,49,147,120,222 120,2032,2366,263,2702,749,1078,669,1155,1710,222,1092,625,134,361,9,3,2088,141,2055,147,1435,49,1169,729,2515,2895,269 2.1206472108366774,-0.3409024311136362,-0.5543007948494578,1.4845046522176364,-0.8287583635800084,0.5142163574940924,0.21440615544338357,0.6194206088649225,0.1684982022009186,-0.16014273539632354,1.6266810625618235,0.21440615544338357,0.682890738977402,2.0577643966472143,1.1865067348823226,3.0232917146470886,3.17018189671295,-0.3596472519831671,1.9991966569128934,-0.3409024311136362,1.9658133945446885,0.009297339019232754,2.515439795372476,0.1684982022009186,0.5542099181825546,-0.6360363435663436,-1.0585470825916556,1.4670922847773513 3193 Envelope 185 466 3.245844829796082 0.0011710264853934 Q567V2,Q9Y2R0,O60830,Q9UDW1,Q9H2D1,P82933,Q9NS69,P80303,Q8N4H5,O43676,P09601,P14406,Q99595,Q9NX14,O96008,Q69YU5,Q8WY22,O43169,Q9UDX5,Q96A26,O75306,Q16611,Q96NB2,Q13505,O14949,Q00325,P06576,Q13423,P21912,O75964,P45880,Q8N2A8,Q99720,P21796,Q9NR28,Q9NZ45,O15173,Q9UBX3,O75208,Q9NQC3,Q96CU9,O14880,Q8WXH0,Q9NVT9,Q9UJZ1,Q15070,O75844,Q9H061,Q9H1E5,Q70HW3,O75431,P17152,Q9H936,P24539,Q9Y5L4,Q9H9B4,P22830,O14925,P22695,Q86UE4,P56134,P13073,Q7KZN9,Q8NFQ8,Q96IX5,Q96KC8,P40939,Q3ZCQ8,Q9P0J0,Q8N183,Q15125,Q8NBU5,Q9Y277,O15504,Q02978,P02545,Q9Y6C9,Q5BJF2,Q92621,Q9NZJ7,P51970,P09669,Q9H2V7,Q9Y4W6,P11717,Q9BSK2,Q9NQZ5,P08574,Q6P4A7,P23786,P47985,Q9UJS0,O43819,Q96RL7,P12236,O95202,O43772,P00403,Q9BQT8,P30536,Q9P035,Q6NUM9,Q14739,Q9BUR5,Q8IWA4,Q6DKK2,O60313,P57105,Q12981,Q9BTX1,Q15388,Q9H3K2,Q10713,Q96P70,P42167,P57088,O00264,P12235,Q5XKP0,P50402,Q9Y619,Q9H4A6,Q9NVI7,Q9HCL2,P05141,O00584,Q8NBN7,Q9Y512,Q9GZY8,Q9BRJ2,Q9BPX6,Q9BXK5,O00165,P56385,Q5T9A4,Q99735,P53701,Q16891,Q9HC21,Q96AY3,Q96TA2,O75746,Q6UXV4,Q5SNT2,Q8WWC4,P05067,Q6ZRP7,Q6PI78,O43615,O95674,Q96TC7,Q53H12,Q99623,O95831,O75880,O75027,Q9UBM7,Q96S66,O95168,Q9NVH1,Q14728,Q6NUK1,Q9Y320,Q8IYU8,P52789,P53007,P49748,Q8NAN2,Q96AG4,Q9BTV4,Q9NX63,O15397,Q7Z7H8,Q9BWH2,Q8N1F7,Q12769,O15228,Q9Y5J9,Q9Y371,Q8NFH4,Q9UH99,Q9UBF8,Q9BVC6,Q15154,P42345 Localization GO Cellular component msigdb_gocc 3,4,5,6,7,521,10,14,15,16,17,18,19,530,525,22,23,25,28,31,543,544,546,36,37,554,552,43,553,47,48,559,50,51,570,54,56,57,563,59,60,562,575,576,577,65,67,68,75,77,583,592,593,83,602,601,596,92,97,102,618,109,112,626,637,125,631,639,129,641,131,647,135,642,644,643,143,144,661,148,656,652,155,677,669,162,163,668,166,167,679,169,175,178,179,190,191,195,197,200,203,207,210,213,218,219,221,222,223,227,232,234,236,237,249,255,258,259,260,261,267,268,277,281,284,285,287,290,299,302,301,307,303,305,309,314,317,318,319,328,348,350,352,356,357,360,362,375,376,377,384,387,388,389,395,397,400,403,404,408,411,419,423,425,435,440,455,457,458,460,461,453,466,479,477,474,471,488,487,494,497,496,495,492,500 1729,303,2540,258,3036,1103,1249,832,1196,285,1151,3169,1785,562,92,37,2032,2033,56,471,2650,453,642,25,716,2487,376,1760,16,191,175,221,937,1555,5,397,2774,563,876,543,1222,958,583,2072,1557,1789,739,2827,1047,350,67,395,1281,47,1106,1152,690,769,404,1963,190,847,740,1048,377,389,525,888,195,643,2790,360,284,552,3095,3108,2368,668,2183,1860,1622,17,652,2428,1650,1153,2458,3138,669,2106,259,179,1016,2740,109,1929,18,770,922,592,3073,960,2581,2252,3040,981,719,51,553,2704,97,596,1969,167,83,1333,2906,2185,2959,2723,2678,200,1795,1284,1202,2355,786,1157,2038,983,1032,3190,1179,2465,631,1417,249,500,1034,1736,1108,1052,1829,48,1564,2919,679,2932,1001,2582,455,2079,1037,3049,2991,2374,261,923,1528,1531,656,2404,435,1183,2524,1767,440,317,1086,2188,1088,721,2218,2315,618,305,255,222,1308,1337,1625,892,2934,1110,2794,818,14,1421,1339,2410,1533,1340,1310,521,554,3076,1362,644,680,236,3124,474,1133,223,2747,1363,1312,1629,1536,1574,43,36,1807,943,710,2018,868,411,210,2167,2763,65,131,1288,492,232,2168,821,2815,544,1507,1002,318,639,387,3,144,1316,1161,356,987,895,309,2710,2019,260,22,219,2856,419,207,790,166,375,1396,809,352,362,77,112,2231,945,1905,2329,466,1478,102,1775,218,1582,969,1137,2506,425,1811,641,477,559,946,1097,15,928,1269,1719,2121,457,287,647,989,1545,1455,724,494,855,626,1907,2021,871,1139,1320,2333,357,575,23,2442,2818,1238,1211,661,856,1239,881,31,1212,458,328,1024,948,60,2567,2127,1723,776,1064,1190,637,125,546,237,178,2534,403,1042,348,384,3151,1295,1485,1116,19,388,50,314,883,301,812,197,302,712,162,1117,460,227,2242,2201,213,3189,495,1488,2787,1843,1027,479,307,800,972,1726,1243,1489,704,1950,826,1324,299,68,1007,75,7,155,802,234,268,2172,931,2823,593,2806,601,2824,1512,1327,1273,319,281,2875,727,2595,59,1244,163,570,1245,2448,1374,10,2450,842,2421,1328,408,277,576,2027,530,461,753,1377,54,148,2674,1514,1848,203,129,1493,861,496,400,1588,57,6,28,1406,497,1590,169,577,1917,2177,2479,2130,2394,862,135,1463,4,1782,912,423,487,2344,1551,2647,1031,1409,2995,677,290,2483,488,754,602,863,267,143,935 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3193 Nucleotide transport 11 13 3.224504365692365 0.0012619093250307 O43808,P12235,Q9BSK2,Q6NUK1,Q9H2D1,Q08722,P12236,Q99808,Q8TB61,P05141,Q9HC21 Processes and pathways GO Biological process msigdb_gobp 444,259,162,419,7,306,179,372,89,284,319 444,284,259,179,866,306,419,89,484,372,162,7,319 0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,0.39013449402256833,1.3408498426869389,1.0416622545332883,2.2225958317358057,0.9320183829658302,1.1663992693165688,1.8971479790749635,3.043830354362099,1.293823383957412 3193 Respirasome 11 40 3.215881075527064 0.0013004471058231 Q9P0J0,P22695,P00403,O14949,Q9UDW1,Q13423,P13073,O43676,Q7KZN9,P14406,Q96CU9 Localization GO Cellular component msigdb_gocc 129,97,195,37,6,43,109,16,112,18,60 2540,832,37,16,876,543,958,1557,404,1963,847,195,668,652,1153,109,18,770,922,3040,981,553,97,2959,1795,1284,679,3049,656,43,1507,1002,219,112,60,530,129,6,862,935 -0.6777844648834328,0.4182557487269513,2.58685650649295,2.850934877568107,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.0629537868319574,-0.303787854117314,0.4042351666901161,1.751667447018552,0.6194206088649225,0.6322515068949177,0.1684982022009186,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,-1.4118743308181245,0.2891251966313216,0.8167483885125356,2.1932323689347277,-1.2051532199617174,-0.213128942203161,0.09011573382996567,0.6065201023101452,-1.4386772460322241,0.6322515068949177,2.5443983795118403,-0.04041324981336907,0.27435692511880505,1.6427531946624607,2.1451816415421097,2.356841664788679,0.8751148153965543,2.0831876730587275,3.1003852237037637,0.4042351666901161,0.3329162614491058 3193 Phagocytic vesicle membrane 8 25 3.209147934186221 0.0013312897601145 P13473,Q93050,P61026,P11279,P04439,Q03518,Q15907,Q9Y487 Localization GO Cellular component msigdb_gocc 72,208,430,206,275,152,216,88 2301,903,1304,275,499,206,72,1679,2185,1181,890,1085,1979,430,1361,1391,152,1424,1807,216,1835,208,1350,1850,88 -0.51428752530657,0.34734463722339803,0.07415070895816572,1.4495286247621895,0.9094287765563077,1.7057429944746445,2.291063262623579,-0.14270834812699967,-0.43590826117893794,0.15301100508827867,0.36168996784734275,0.21440615544338357,-0.303787854117314,1.0093338760985888,0.04192461851956566,0.02566161901174243,1.9386564503168657,0.009297339019232754,-0.213128942203161,1.6586937760640963,-0.23102262249362931,1.7057429944746445,0.05808732403364699,-0.23102262249362931,2.2284083926639537 3193 Sterol metabolic process 20 40 3.208542105153125 0.0013340977346907 Q9BQE5,Q15125,Q9UKR5,Q8WTV0,Q9UBM7,P35610,Q14534,Q16850,P04062,Q14849,P49748,P04035,Q14739,Q15392,P37268,P05067,Q15800,O75845,P61916,P16435 Processes and pathways GO Biological process msigdb_gobp 1,131,266,141,400,410,297,170,53,58,455,205,210,84,99,360,107,238,491,248 2033,238,1015,888,205,53,360,2403,2077,248,2704,2705,410,99,526,2706,655,455,2684,2948,491,2043,2981,3120,297,210,58,1903,131,2872,84,788,107,170,1987,141,1,400,1461,266 -0.3409024311136362,1.5776579775269348,0.25950170179577764,0.36168996784734275,1.7057429944746445,2.4355304023078563,1.1865067348823226,-0.5745186791895069,-0.3596472519831671,1.5358542924197818,-0.8287583635800084,-0.8287583635800084,1.05233382643295,2.1872987787678158,0.8751148153965543,-0.8287583635800084,0.6322515068949177,0.9654822230844401,-0.8067138905481915,-1.180235642836601,0.9207519138862322,-0.3409024311136362,-1.2555878176142559,-1.8085693165877301,1.38683389940539,1.6979807301199143,2.394036011434074,-0.2671646500903092,2.070521741578072,-1.0347727466327314,2.2399742438327923,0.4735513630461408,2.163357703140536,1.8475085220023033,-0.303787854117314,1.9991966569128934,3.268320628293502,1.0840404415884148,-0.007169221259632773,1.4758172511688186 3193 Primary mitochondrial disease 46 95 3.190919015876996 0.0014182102670248 Q9P0J0,Q8N183,P12235,Q9Y2R0,Q5XKP0,Q53H12,O95831,P14927,Q9Y2R9,O75880,Q9BSH4,Q9NX14,O43676,Q9Y6M9,O75879,Q96GW9,O75306,Q07021,P08574,O14949,Q6P4A7,P47985,O43819,P54098,Q9UBX3,O75208,Q96CU9,Q96RR1,P00403,Q9BW92,Q9BRT2,Q9BQT8,O00483,Q70HW3,Q9Y276,Q9NPL8,Q6DKK2,O95299,O60313,P22695,Q99797,P13073,Q5T2R2,Q7KZN9,O75251,Q96IX5 Drugs and Diseases Protein Atlas Disease involvement protein_atlas_disease_involvement 129,641,259,4,260,387,389,770,912,395,910,530,16,935,784,541,543,799,668,37,166,679,175,686,57,563,60,841,195,580,712,197,832,77,862,727,219,847,221,97,359,109,493,112,876,637 2540,832,37,16,3046,175,221,563,876,543,958,1557,784,395,847,389,195,2076,668,2183,259,109,770,3040,981,97,1333,2959,1795,1034,2622,679,2290,3049,1183,2112,686,1421,1310,1868,799,1002,387,1315,967,1111,493,2270,260,219,166,77,112,1477,3098,641,1398,1907,1368,2021,60,541,637,995,841,359,2570,197,712,910,2242,580,1547,1044,931,2824,2698,727,530,1697,1848,129,2736,57,862,1463,4,912,1379,2068,2344,1031,1409,2454,935 -0.6777844648834328,0.4182557487269513,2.58685650649295,2.850934877568107,-1.4386772460322241,1.8185362415383943,1.6266810625618235,0.7929788244184839,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,0.4735513630461408,1.1049253152266847,0.4042351666901161,1.1152930343193794,1.751667447018552,-0.3596472519831671,0.6194206088649225,-0.43590826117893794,1.5017677751833673,2.1512615372917634,0.48718206135466036,-1.4118743308181245,0.2891251966313216,2.1932323689347277,0.05808732403364699,-1.2051532199617174,-0.213128942203161,0.2445587153188426,-0.7415449896710221,0.6065201023101452,-0.494489054305589,-1.4386772460322241,0.15301100508827867,-0.3785188752723304,0.5935493889180543,0.009297339019232754,0.07415070895816572,-0.24903411518852805,0.45984406883424556,0.27435692511880505,1.125611440557737,0.07415070895816572,0.30380731745916084,0.19919490676105286,0.9207519138862322,-0.4748273403029004,1.5017677751833673,1.6427531946624607,1.8760367688861144,2.2514617717609795,2.1451816415421097,-0.023739075165896593,-1.6327200595968123,0.6577068359941382,0.02566161901174243,-0.2671646500903092,0.04192461851956566,-0.32228307221127694,2.356841664788679,0.8519470898097677,0.6703324293561015,0.2891251966313216,0.4182557487269513,1.1964900873490003,-0.6777844648834328,1.751667447018552,0.5673949130081869,0.34734463722339803,-0.4553008972742839,0.7689615842364066,-0.05719278632694883,0.2445587153188426,0.3329162614491058,-0.9645358333127365,-0.8067138905481915,0.5542099181825546,0.8751148153965543,-0.14270834812699967,-0.23102262249362931,2.0831876730587275,-0.8509667351664257,2.39928112695771,0.4042351666901161,-0.007169221259632773,3.129385678191442,0.34734463722339803,0.04192461851956566,-0.3409024311136362,-0.51428752530657,0.25950170179577764,0.02566161901174243,-0.5948794930148794,0.3329162614491058 3193 Nuclear inner membrane 11 19 3.181901791929154 0.0014631142197927 O94901,O75844,P50402,Q5SNT2,Q03252,Q9H1E5,Q9BTV4,Q9UH99,Q99720,Q14739,Q14728 Localization GO Cellular component msigdb_gocc 690,67,261,356,680,75,460,497,50,210,411 67,690,719,1034,1108,261,1337,892,680,1312,411,210,1161,356,989,50,460,75,497 2.329750012077,0.5805078633245453,0.5542099181825546,0.2445587153188426,0.19919490676105286,1.4931547427369818,0.05808732403364699,0.36168996784734275,0.6065201023101452,0.07415070895816572,1.05233382643295,1.6979807301199143,0.1684982022009186,1.1964900873490003,0.2891251966313216,2.5056676046326203,0.9654822230844401,2.2628718108903665,0.9207519138862322 3193 Secondary active transmembrane transporter activity 19 22 3.1810410009218475 0.0014674685924478 P12235,Q02978,Q96ES6,P53985,P05141,P08195,Q00325,P55011,Q9BXP2,P12236,Q9H2J7,Q15758,P53007,Q9UBX3,Q9Y6M7,O95202,Q9H936,Q15043,P51798 Functions GO Molecular function msigdb_gomf 259,644,142,407,284,417,554,558,433,179,705,565,440,57,189,190,593,241,383 190,284,417,259,179,866,3161,383,440,407,558,554,644,241,565,724,142,433,705,593,57,189 1.7667329517528663,1.4228948856937176,1.0416622545332883,1.5017677751833673,1.803880161059405,0.39013449402256833,-2.3972018839891502,1.1358809033740525,0.9875161701203701,1.0629537868319574,0.8048943132507087,0.8167483885125356,0.6450133877649504,1.5693674826960398,0.7929788244184839,0.5542099181825546,1.992569263975948,1.0093338760985888,0.5805078633245453,0.7446925671515504,2.39928112695771,1.7742210599427393 3193 Sphingolipid metabolism 7 12 3.176999299190436 0.0014880739556399 O95470,Q16880,Q13510,Q06136,P16278,P06280,P04062 Processes and pathways KEGG Pathways msigdb_kegg 128,140,45,110,82,244,53 252,1198,557,128,53,244,1258,82,110,45,140,753 1.5188836640650665,0.1374300649717309,0.8048943132507087,2.0894866813375814,2.4355304023078563,1.5526815978228736,0.1059833465335269,2.2399742438327923,2.1512615372917634,2.5348046058833917,2.0123785518790727,0.5142163574940924 3193 Cytochrome complex 6 17 3.1751718672323217 0.0014974777856542 P22695,O14949,Q9UDW1,P13073,Q7KZN9,P14406 Localization GO Cellular component msigdb_gocc 97,37,6,109,112,18 832,37,195,668,652,1153,109,18,770,922,981,97,1284,679,112,6,862 0.4182557487269513,2.58685650649295,1.751667447018552,0.6194206088649225,0.6322515068949177,0.1684982022009186,2.1512615372917634,2.8313023316243195,0.48718206135466036,0.3329162614491058,0.2891251966313216,2.1932323689347277,0.09011573382996567,0.6065201023101452,2.1451816415421097,3.1003852237037637,0.4042351666901161 3193 Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 37 58 3.167776469411004 0.0015360957767687 Q9P0J0,Q8N183,Q9UDW1,P14927,O75880,Q9BSH4,Q9NX14,O43676,P51970,Q9Y6M9,O95168,P09669,Q9H845,O75306,P08574,O14949,P15954,Q9BQ95,P47985,P06576,P21912,O43819,O75964,P56385,Q16134,P00403,O75380,O00483,Q9NPL8,P24539,O95299,P22695,P36542,P20674,P56134,P13073,O75251 Processes and pathways Reactome Pathways msigdb_reactome 129,641,6,770,395,910,530,16,656,935,404,652,931,543,668,37,922,812,679,552,553,175,47,305,821,195,958,832,727,83,847,97,983,981,618,109,876 2540,832,37,16,175,876,543,958,1557,395,1281,47,404,1963,847,195,552,668,652,1153,109,2703,770,922,3040,981,553,97,83,1333,2959,1795,1284,983,2761,1034,679,2932,3049,656,618,305,1133,821,1507,1002,641,1368,812,910,2242,931,727,530,1848,129,6,935 -0.6777844648834328,0.4182557487269513,2.58685650649295,2.850934877568107,1.8185362415383943,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.1049253152266847,0.09011573382996567,2.515439795372476,1.0629537868319574,-0.303787854117314,0.4042351666901161,1.751667447018552,0.8167483885125356,0.6194206088649225,0.6322515068949177,0.1684982022009186,2.1512615372917634,-0.8287583635800084,0.48718206135466036,0.3329162614491058,-1.4118743308181245,0.2891251966313216,0.8167483885125356,2.1932323689347277,2.2399742438327923,0.05808732403364699,-1.2051532199617174,-0.213128942203161,0.09011573382996567,0.2891251966313216,-0.8958829370602809,0.2445587153188426,0.6065201023101452,-1.1555145615983378,-1.4386772460322241,0.6322515068949177,0.6953823294342337,1.3408498426869389,0.1838925440088085,0.4321969562595515,-0.04041324981336907,0.27435692511880505,0.6577068359941382,0.04192461851956566,0.44605949669078204,0.34734463722339803,-0.4553008972742839,0.3329162614491058,0.5542099181825546,0.8751148153965543,-0.23102262249362931,2.0831876730587275,3.1003852237037637,0.3329162614491058 3193 Basal part of cell 19 50 3.157351675618429 0.0015920920936511 P42785,P53985,P78310,Q14254,P08195,P20020,P55011,Q15758,Q9Y6M7,P35613,P02786,O75955,P57105,P11166,P05023,Q15043,Q99808,Q12959,Q6P4Q7 Localization GO Cellular component msigdb_gocc 136,407,536,671,417,291,558,565,189,192,209,338,222,612,363,241,372,625,254 1729,1383,999,2105,338,1254,209,692,363,1676,1522,417,1559,612,1792,2008,1524,2284,1177,291,1827,833,1128,192,866,136,407,798,558,222,1568,536,1091,1424,2499,625,2438,1313,671,241,565,1987,254,1236,1348,2534,372,1883,189,2773 -0.177690185818539,0.02566161901174243,0.27435692511880505,-0.3785188752723304,1.2359622824697312,0.1059833465335269,1.6979807301199143,0.5805078633245453,1.176476578042439,-0.14270834812699967,-0.05719278632694883,1.0416622545332883,-0.07407874008591195,0.7078077588474234,-0.213128942203161,-0.32228307221127694,-0.05719278632694883,-0.494489054305589,0.15301100508827867,1.3959088234962316,-0.23102262249362931,0.4182557487269513,0.1838925440088085,1.7592151429408447,0.39013449402256833,2.0384546855538916,1.0629537868319574,0.45984406883424556,0.8048943132507087,1.6266810625618235,-0.07407874008591195,0.8519470898097677,0.21440615544338357,0.009297339019232754,-0.6360363435663436,0.682890738977402,-0.5948794930148794,0.07415070895816572,0.6194206088649225,1.5693674826960398,0.7929788244184839,-0.303787854117314,1.5188836640650665,0.12175448251162654,0.05808732403364699,-0.656835659642823,1.1663992693165688,-0.24903411518852805,1.7742210599427393,-0.8958829370602809 3193 Protein insertion into membrane 14 26 3.143821891406139 0.0016675690171479 Q9Y512,Q9P0J0,Q15070,Q53H12,P46379,Q9Y5J9,Q5J8M3,O14737,Q8WWC4,Q9NS69,O43681,Q96A33,Q9NPA0,Q15629 Processes and pathways GO Biological process msigdb_gobp 290,129,65,387,351,488,550,294,357,10,557,174,239,114 294,557,919,1152,1413,2373,2832,351,941,893,65,114,387,550,2913,909,357,174,239,10,1170,129,862,290,488,602 1.38683389940539,0.8048943132507087,0.3329162614491058,0.1684982022009186,0.009297339019232754,-0.5543007948494578,-0.9877693062177954,1.2064269794639189,0.3184040786732402,0.36168996784734275,2.3406400045953175,2.1390803803002107,1.125611440557737,0.8285415486462114,-1.1066521830470757,0.34734463722339803,1.1964900873490003,1.825821535867474,1.5776579775269348,3.0024397548003465,0.1684982022009186,2.0831876730587275,0.4042351666901161,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 Glycoside hydrolase superfamily [IPR017853] 10 14 3.1363971034660496 0.0017103744304736 P08195,Q9BTY2,P06865,P07686,P10253,P16278,P06280,P04062,O60502,P54802 Sequence InterPro Superfamily interpro_homologous_superfamily 417,257,224,584,145,82,244,53,215,126 215,53,591,244,224,584,417,145,82,1260,126,1429,257,1066 1.6586937760640963,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,0.7568588077238091,1.0416622545332883,1.9658133945446885,2.2399742438327923,0.1059833465335269,2.095763221365341,0.009297339019232754,1.510343999684222,0.22952714396117282 3193 Endocytic vesicle membrane 10 43 3.13613546363981 0.001711901108913 P13473,Q14108,Q5KU26,Q8WTV0,Q93050,P11279,P02786,Q03518,Q15907,Q9Y487 Localization GO Cellular component msigdb_gocc 72,9,201,141,208,206,209,152,216,88 2301,2302,903,2702,749,1304,209,275,499,206,669,72,1679,1155,2185,1181,890,1085,1054,1979,430,1361,2407,2589,1391,152,1424,1425,2381,1807,9,771,2779,216,201,1987,1835,141,208,1511,1350,1850,88 -0.51428752530657,-0.51428752530657,0.34734463722339803,-0.8287583635800084,0.5142163574940924,0.07415070895816572,1.6979807301199143,1.4495286247621895,0.9094287765563077,1.7057429944746445,0.6194206088649225,2.291063262623579,-0.14270834812699967,0.1684982022009186,-0.43590826117893794,0.15301100508827867,0.36168996784734275,0.21440615544338357,0.22952714396117282,-0.303787854117314,1.0093338760985888,0.04192461851956566,-0.5745186791895069,-0.6988844633124501,0.02566161901174243,1.9386564503168657,0.009297339019232754,0.009297339019232754,-0.5543007948494578,-0.213128942203161,3.0232917146470886,0.48718206135466036,-0.9185947277776126,1.6586937760640963,1.7364816398521126,-0.303787854117314,-0.23102262249362931,1.9991966569128934,1.7057429944746445,-0.04041324981336907,0.05808732403364699,-0.23102262249362931,2.2284083926639537 3193 Lipid droplet 9 31 3.1339260315734703 0.0017248432964456 Q8NBQ5,Q07065,Q96RL7,O43760,Q99720,Q8NF37,Q01105,Q8NBX0,Q9H6V9 Localization GO Cellular component msigdb_gocc 324,73,178,78,50,181,278,154,62 2542,78,1555,1175,1048,888,2790,1522,959,655,1530,890,327,2584,278,73,752,788,1811,324,154,181,1480,560,178,50,803,62,860,2247,1439 -0.6777844648834328,2.2457277457630314,-0.07407874008591195,0.15301100508827867,0.22952714396117282,0.36168996784734275,-0.9414783391764264,-0.05719278632694883,0.30380731745916084,0.6322515068949177,-0.05719278632694883,0.36168996784734275,1.2650915011001496,-0.6988844633124501,1.4406894094750298,2.28546270022205,0.5142163574940924,0.4735513630461408,-0.213128942203161,1.284289708677259,1.9318034306318732,1.7965090219596693,-0.023739075165896593,0.8048943132507087,1.8112225085127378,2.5056676046326203,0.45984406883424556,2.3514587661376916,0.4042351666901161,-0.4553008972742839,0.009297339019232754 3193 Predicted secreted proteins 28 48 3.1288543048569606 0.001754892991288 Q9H6E4,Q9BTY2,P80303,P78310,O00584,Q02818,Q07021,Q15165,P43490,Q9NZ08,O94813,P84157,Q9HB40,Q9Y4P3,P04083,Q9UMX5,O94919,Q99584,P02786,Q14667,Q9BUR5,O75718,Q9BRX8,P05067,Q8N128,P61916,Q08380,P26583 Functions Protein Atlas Protein class protein_atlas_protein_class 778,257,14,536,285,29,799,33,535,159,794,165,42,183,692,194,199,336,209,722,213,717,611,360,123,491,251,630 285,1785,1705,2397,717,794,199,209,692,360,2282,1522,1200,1651,2460,2008,2620,630,535,2658,2659,491,536,14,1626,165,29,799,251,2437,1058,722,33,809,123,3175,990,992,336,611,257,213,3019,778,42,159,194,183 1.413939040620315,-0.213128942203161,-0.16014273539632354,-0.5745186791895069,0.5542099181825546,0.45984406883424556,1.7364816398521126,1.6979807301199143,0.5805078633245453,1.1865067348823226,-0.494489054305589,-0.05719278632694883,0.1374300649717309,-0.12538587769838372,-0.6153848387722859,-0.32228307221127694,-0.7415449896710221,0.6703324293561015,0.8519470898097677,-0.7848314137948916,-0.7848314137948916,0.9207519138862322,0.8519470898097677,2.919464172904466,-0.1081741936250891,1.8760367688861144,2.6595734089805485,0.45984406883424556,1.5273870138763348,-0.5948794930148794,0.22952714396117282,0.5542099181825546,2.6327069548105406,0.44605949669078204,2.1082494009679316,-2.85051601606499,0.2891251966313216,0.2891251966313216,1.2457167051043052,0.7201675789757652,1.510343999684222,1.682361685022864,-1.3327768033414031,0.48718206135466036,2.563411491546392,1.9041316359550924,1.7592151429408447,1.7965090219596693 3193 Establishment of protein localization to membrane 34 87 3.128412346701384 0.0017575342370417 P43307,Q9P0J0,P40855,Q53H12,P98194,Q9NS69,Q9H4A6,Q9Y512,Q5J8M3,O14737,Q9GZY8,O43681,Q96A33,P61026,Q99442,Q9UGP8,P31751,Q15070,Q15904,Q8N2H4,Q9Y5L4,O60725,Q15907,Q9UHB9,P46379,Q9Y5J9,Q8WWC4,Q9UPN3,Q9NPA0,Q9HD20,Q15629,P27105,P49458,Q4J6C6 Processes and pathways GO Biological process msigdb_gobp 0,129,386,387,522,10,268,290,550,294,299,557,174,430,432,571,564,65,323,69,602,87,216,349,351,488,357,622,239,113,114,115,374,505 1729,1013,294,715,2033,557,919,87,2827,2576,1152,1048,1676,1413,2005,3064,115,2373,2908,564,2832,2550,386,2744,0,351,694,374,890,2468,2375,2899,1979,2434,430,941,3119,522,1605,1090,2499,2438,820,893,752,65,114,323,216,505,2226,387,550,2913,2798,761,69,909,647,357,174,949,432,299,930,268,932,1952,113,1147,239,1244,10,1954,1170,129,571,349,2478,1672,831,622,862,2481,290,488,602 -0.177690185818539,0.25950170179577764,1.38683389940539,0.5542099181825546,-0.3409024311136362,0.8048943132507087,0.3329162614491058,2.2284083926639537,-0.9877693062177954,-0.6988844633124501,0.1684982022009186,0.22952714396117282,-0.14270834812699967,0.009297339019232754,-0.32228307221127694,-1.492956015355766,2.132957634741071,-0.5543007948494578,-1.1066521830470757,0.7929788244184839,-0.9877693062177954,-0.6777844648834328,1.125611440557737,-0.8733409382481655,3.2740327620941194,1.2064269794639189,0.5805078633245453,1.1562744576555442,0.36168996784734275,-0.6153848387722859,-0.5543007948494578,-1.082506135737104,-0.303787854117314,-0.5948794930148794,1.0093338760985888,0.3184040786732402,-1.8085693165877301,0.8866106862369233,-0.09107218097239303,0.21440615544338357,-0.6360363435663436,-0.5948794930148794,0.4321969562595515,0.36168996784734275,0.5142163574940924,2.3406400045953175,2.1390803803002107,1.284289708677259,1.6586937760640963,0.9094287765563077,-0.4553008972742839,1.125611440557737,0.8285415486462114,-1.1066521830470757,-0.9414783391764264,0.5007368375870117,2.31327983578579,0.34734463722339803,0.6450133877649504,1.1964900873490003,1.825821535867474,0.3184040786732402,1.0093338760985888,1.38683389940539,0.3329162614491058,1.4670922847773513,0.3329162614491058,-0.28541547461577405,2.1451816415421097,0.1838925440088085,1.5776579775269348,0.12175448251162654,3.0024397548003465,-0.28541547461577405,0.1684982022009186,2.0831876730587275,0.7929788244184839,1.216317751801572,-0.6153848387722859,-0.12538587769838372,0.4321969562595515,0.6953823294342337,0.4042351666901161,-0.6153848387722859,1.4049437781239236,0.9320183829658302,0.7324623353077244 3193 Protein transmembrane transport 14 24 3.12590118499596 0.0017726110348159 O60830,O95831,O75381,Q15388,Q9NS69,Q99442,Q15629,O96008,Q99595,P49755,Q9UGP8,P31751,O43615,O14925 Processes and pathways GO Biological process msigdb_gobp 5,389,263,232,10,432,114,525,19,304,571,564,376,92 92,376,5,263,1152,389,525,2458,1306,564,304,2899,2434,941,232,114,639,2798,928,432,19,1327,10,571 2.2109109040904884,1.1461017884280336,3.1165747016179965,1.4845046522176364,0.1684982022009186,1.1152930343193794,0.8751148153965543,-0.6153848387722859,0.07415070895816572,0.7929788244184839,1.3408498426869389,-1.082506135737104,-0.5948794930148794,0.3184040786732402,1.6023224295792171,2.1390803803002107,0.6577068359941382,-0.9414783391764264,0.3329162614491058,1.0093338760985888,2.8113998714497686,0.07415070895816572,3.0024397548003465,0.7929788244184839 3193 Organelle membrane contact site 10 16 3.122213021152972 0.0017949700863666 Q96TC7,Q9NTJ5,Q5XKP0,Q9Y320,Q15388,P51572,Q8NHP6,Q96S66,P27824,Q14849 Localization GO Cellular component msigdb_gocc 384,486,260,423,232,327,340,403,311,58 666,1125,1555,525,311,327,1807,58,232,260,340,403,384,1350,486,423 0.6194206088649225,0.1838925440088085,-0.07407874008591195,0.8751148153965543,1.3221664240422288,1.2650915011001496,-0.213128942203161,2.394036011434074,1.6023224295792171,1.5017677751833673,1.2359622824697312,1.0735225288658525,1.1358809033740525,0.05808732403364699,0.9320183829658302,1.03093867386121 3193 Pigment granule 25 59 3.1207770496712213 0.001803745383766 Q15286,P61019,Q92820,O14773,P08195,P07237,P49755,P27824,Q15758,O43852,P21281,P35613,Q93050,P11279,P02786,Q92542,O75955,P11166,P04843,P05023,P27105,P62820,P62258,P55209,P57088 Localization GO Cellular component msigdb_gocc 771,520,529,150,417,684,304,311,565,315,693,192,208,206,209,211,338,612,490,363,115,758,633,502,255 150,315,903,338,209,490,363,1078,684,1522,1413,1387,417,1559,1622,2351,612,206,1597,1443,1679,693,2620,3129,115,311,1474,2037,1972,192,866,1084,304,2257,1528,1530,890,798,502,255,520,1130,633,758,1625,2041,2589,1807,944,1429,1937,771,565,2530,2055,211,529,208,2914 1.945483805688231,1.3033138565109923,0.34734463722339803,1.2359622824697312,1.6979807301199143,0.9207519138862322,1.176476578042439,0.21440615544338357,0.5935493889180543,-0.05719278632694883,0.009297339019232754,0.02566161901174243,1.0416622545332883,-0.07407874008591195,-0.1081741936250891,-0.5342242617338631,0.7078077588474234,1.7057429944746445,-0.09107218097239303,-0.007169221259632773,-0.14270834812699967,0.5805078633245453,-0.7415449896710221,-1.9000405921739463,2.132957634741071,1.3221664240422288,-0.023739075165896593,-0.3409024311136362,-0.303787854117314,1.7592151429408447,0.39013449402256833,0.21440615544338357,1.3408498426869389,-0.4748273403029004,-0.05719278632694883,-0.05719278632694883,0.36168996784734275,0.45984406883424556,0.9094287765563077,1.510343999684222,0.8866106862369233,0.1838925440088085,0.6703324293561015,0.5007368375870117,-0.1081741936250891,-0.3409024311136362,-0.6988844633124501,-0.213128942203161,0.3184040786732402,0.009297339019232754,-0.28541547461577405,0.48718206135466036,0.7929788244184839,-0.656835659642823,-0.3409024311136362,1.682361685022864,0.8751148153965543,1.7057429944746445,-1.1066521830470757 3193 Snare complex 9 17 3.119137238001992 0.0018138145712294 O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190,Q12981 Localization GO Cellular component msigdb_gocc 63,229,39,429,462,442,345,253,223 2301,462,345,782,63,903,229,472,1085,2080,1424,223,253,442,1487,39,429 -0.51428752530657,0.9543830980982788,1.216317751801572,0.4735513630461408,2.346058243177083,0.34734463722339803,1.6104756568747511,0.9432286304255554,0.21440615544338357,-0.3596472519831671,0.009297339019232754,1.6266810625618235,1.5188836640650665,0.9875161701203701,-0.023739075165896593,2.572831939044648,1.0201626829533696 3193 Coated vesicle 26 89 3.1169592216860944 0.0018272684545115 P24390,Q14108,P53634,P04439,O43731,Q9BVK6,Q8N511,Q9UBR2,O00165,P49755,Q15363,Q12907,P49257,P51572,P02786,Q9NR31,O15126,O14653,Q9Y3B3,Q5VW38,P42892,P05067,Q9Y3A6,Q9Y282,P10321,Q13190 Localization GO Cellular component msigdb_gocc 2,9,402,275,26,415,161,293,303,304,61,574,447,327,209,594,463,462,95,101,100,360,498,119,499,253 303,1013,1440,864,2486,462,715,463,26,2366,2104,1961,2424,903,2702,2651,2182,1521,749,1304,209,275,360,1677,499,2458,2351,669,1679,1155,2,1156,100,1053,447,304,1181,1203,327,1085,2962,2659,402,1054,2604,2315,1979,1055,1390,2407,2589,1391,574,253,2265,9,1752,771,61,2294,1632,2269,1987,101,599,161,1063,1511,415,1616,1881,1351,1147,594,2246,1298,2807,2101,293,2894,2953,1672,2177,119,498,95,1701,1220,1854 1.3408498426869389,0.25950170179577764,-0.007169221259632773,0.39013449402256833,-0.6360363435663436,0.9543830980982788,0.5542099181825546,0.9543830980982788,2.6816050945494077,-0.5543007948494578,-0.3785188752723304,-0.303787854117314,-0.5948794930148794,0.34734463722339803,-0.8287583635800084,-0.7848314137948916,-0.43590826117893794,-0.05719278632694883,0.5142163574940924,0.07415070895816572,1.6979807301199143,1.4495286247621895,1.1865067348823226,-0.14270834812699967,0.9094287765563077,-0.6153848387722859,-0.5342242617338631,0.6194206088649225,-0.14270834812699967,0.1684982022009186,3.21572160468917,0.1684982022009186,2.181344630255124,0.22952714396117282,0.9765264378161742,1.3408498426869389,0.15301100508827867,0.1374300649717309,1.2650915011001496,0.21440615544338357,-1.2051532199617174,-0.7848314137948916,1.0735225288658525,0.22952714396117282,-0.7201373856155233,-0.51428752530657,-0.303787854117314,0.22952714396117282,0.02566161901174243,-0.5745186791895069,-0.6988844633124501,0.02566161901174243,0.7810014179820873,1.5188836640650665,-0.4748273403029004,3.0232917146470886,-0.177690185818539,0.48718206135466036,2.3514587661376916,-0.494489054305589,-0.1081741936250891,-0.4748273403029004,-0.303787854117314,2.181344630255124,0.7324623353077244,1.8971479790749635,0.22952714396117282,-0.04041324981336907,1.05233382643295,-0.09107218097239303,-0.24903411518852805,0.05808732403364699,0.1838925440088085,0.7446925671515504,-0.4553008972742839,0.09011573382996567,-0.9414783391764264,-0.3596472519831671,1.3959088234962316,-1.0585470825916556,-1.180235642836601,-0.12538587769838372,-0.41664798954862137,2.1268132851345656,0.9207519138862322,2.1991455126433834,-0.14270834812699967,0.1374300649717309,-0.23102262249362931 3193 primary active transporter 13 22 3.1115006462014057 0.0018613906661573 Q96NB2,P20020,P16615,Q6P4A7,O75381,Q15388,Q9NS69,P98194,Q8N4H5,P05023,O96008,Q9BUN8,Q15758 Functions Panther Protein class panther_protein_class 546,291,196,166,263,232,10,522,15,363,525,147,565 2397,263,1152,525,363,1676,3064,1016,196,291,798,522,232,565,166,15,546,147,705,601,1327,10 -0.5745186791895069,1.4845046522176364,0.1684982022009186,0.8751148153965543,1.176476578042439,-0.14270834812699967,-1.492956015355766,0.25950170179577764,1.751667447018552,1.3959088234962316,0.45984406883424556,0.8866106862369233,1.6023224295792171,0.7929788244184839,1.8760367688861144,2.9120109684113684,0.8402742865808962,1.9658133945446885,0.5805078633245453,0.7324623353077244,0.07415070895816572,3.0024397548003465 3193 secondary carrier transporter 12 14 3.1072219953419817 0.0018885452092876 O75746,Q9BQT8,Q9UJS0,Q96ES6,P55011,Q9BXP2,Q9H936,Q15043,Q9UBX3,Q8TB61,Q9Y6M7,O95202 Functions Panther Protein class panther_protein_class 350,197,169,142,558,433,593,241,57,89,189,190 350,190,558,644,241,1209,89,142,197,433,593,57,169,189 1.2064269794639189,1.7667329517528663,0.8048943132507087,0.6450133877649504,1.5693674826960398,0.1374300649717309,2.2225958317358057,1.992569263975948,1.751667447018552,1.0093338760985888,0.7446925671515504,2.39928112695771,1.854681789652418,1.7742210599427393 3193 Sphingolipid metabolism 7 10 3.104801221710533 0.0019040693946392 O95470,Q16880,Q13510,Q06136,P17900,P07602,P04062 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 128,140,45,110,79,20,53 252,1198,128,53,20,79,110,45,140,556 1.5188836640650665,0.1374300649717309,2.0894866813375814,2.4355304023078563,2.762496989040066,2.2457277457630314,2.1512615372917634,2.5348046058833917,2.0123785518790727,0.8167483885125356 3193 Amino acid transport 15 20 3.09468094171039 0.0019702471647005 O75746,P08195,Q96NB2,Q6P4A7,Q8TDW0,Q9UJS0,Q9Y619,O75915,P55011,Q9H936,O60831,Q7L0J3,Q9H2J7,Q9H9B4,Q15758 Processes and pathways GO Biological process msigdb_gobp 350,417,546,166,484,169,267,551,558,593,489,149,705,601,565 2346,2031,489,350,551,1078,417,558,2555,752,565,166,149,484,546,705,593,601,169,267 -0.5342242617338631,-0.3409024311136362,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.21440615544338357,1.0416622545332883,0.8048943132507087,-0.6777844648834328,0.5142163574940924,0.7929788244184839,1.8760367688861144,1.952285648216789,0.9320183829658302,0.8402742865808962,0.5805078633245453,0.7446925671515504,0.7324623353077244,1.854681789652418,1.4758172511688186 3193 Sensorimotor neuropathy 15 29 3.086335985458487 0.0020263970574603 P00403,Q9Y2R0,Q13217,P40939,O95831,Q5KU26,P05023,Q9NR77,Q8N2K0,Q9NZJ7,P07602,Q15120,P07196,Q9Y4W6,O60313 Drugs and Diseases Human Phenotype Ontology msigdb_hp 195,4,549,631,389,201,363,49,371,148,20,476,438,677,221 1249,1198,221,389,195,363,438,20,1825,3129,2010,631,866,1388,850,686,2584,2218,1342,549,476,201,371,1839,49,1460,148,4,677 0.1059833465335269,0.1374300649717309,1.6266810625618235,1.1152930343193794,1.751667447018552,1.176476578042439,0.9875161701203701,2.762496989040066,-0.23102262249362931,-1.9000405921739463,-0.32228307221127694,0.6703324293561015,0.39013449402256833,0.02566161901174243,0.4042351666901161,0.5935493889180543,-0.6988844633124501,-0.4553008972742839,0.05808732403364699,0.8285415486462114,0.9432286304255554,1.7364816398521126,1.1663992693165688,-0.23102262249362931,2.515439795372476,-0.007169221259632773,1.9590621281540601,3.129385678191442,0.6194206088649225 3193 Transport vesicle membrane 17 45 3.085938751020169 0.0020291061491441 O60499,P49257,P20020,O75592,O43760,O15126,P49755,P04439,Q7L0J3,O14653,Q86Y82,Q13190,Q15907,O76024,Q15363,Q9Y3B3,O95295 Localization GO Cellular component msigdb_gocc 63,447,291,445,78,463,304,275,149,462,442,253,216,247,61,95,409 1249,462,715,463,2366,78,63,1961,2424,903,445,247,2651,409,2182,1521,749,1304,275,1677,499,291,1679,447,304,890,1085,2604,2315,1130,758,2589,253,771,61,2294,1632,216,149,442,2095,594,2894,95,1854 0.1059833465335269,0.9543830980982788,0.5542099181825546,0.9543830980982788,-0.5543007948494578,2.2457277457630314,2.346058243177083,-0.303787854117314,-0.5948794930148794,0.34734463722339803,0.9765264378161742,1.5358542924197818,-0.7848314137948916,1.05233382643295,-0.43590826117893794,-0.05719278632694883,0.5142163574940924,0.07415070895816572,1.4495286247621895,-0.14270834812699967,0.9094287765563077,1.3959088234962316,-0.14270834812699967,0.9765264378161742,1.3408498426869389,0.36168996784734275,0.21440615544338357,-0.7201373856155233,-0.51428752530657,0.1838925440088085,0.5007368375870117,-0.6988844633124501,1.5188836640650665,0.48718206135466036,2.3514587661376916,-0.494489054305589,-0.1081741936250891,1.6586937760640963,1.952285648216789,0.9875161701203701,-0.3596472519831671,0.7446925671515504,-1.0585470825916556,2.1991455126433834,-0.23102262249362931 3193 Liposaccharide metabolic process 12 15 3.080837257030524 0.0020641943808694 P06865,P07686,Q16880,Q9H490,P17900,P04066,Q92643,P16278,P06280,P04062,Q99805,Q8NBX0 Processes and pathways GO Biological process msigdb_gobp 224,584,140,366,79,591,468,82,244,53,343,154 756,53,591,244,224,584,82,79,140,154,468,1401,663,343,366 0.5007368375870117,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,0.7568588077238091,2.2399742438327923,2.2457277457630314,2.0123785518790727,1.9318034306318732,0.9543830980982788,0.02566161901174243,0.6322515068949177,1.2261627415331837,1.176476578042439 3193 Primary active transmembrane transporter activity 23 48 3.0798859577489965 0.0020707987001158 Q9P0J0,Q9UDW1,P98194,O75027,O43676,P51970,O95168,Q03518,O75306,P08574,P20020,P47985,P06576,P08183,P00403,P16615,P28288,Q15388,P13073,P05023,Q7KZN9,Q9HD20,P51798 Functions GO Molecular function msigdb_gomf 129,6,522,397,16,656,404,152,543,668,291,679,552,176,195,196,473,232,109,363,112,113,383 2540,832,16,397,876,543,958,1557,404,1963,847,195,363,1676,552,176,668,1153,109,196,3040,291,981,693,2547,473,2959,1284,833,962,2998,679,3049,383,656,1361,522,152,232,1507,1002,112,113,2448,129,6,2151,935 -0.6777844648834328,0.4182557487269513,2.850934877568107,1.0945079100252835,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.0629537868319574,-0.303787854117314,0.4042351666901161,1.751667447018552,1.176476578042439,-0.14270834812699967,0.8167483885125356,1.8112225085127378,0.6194206088649225,0.1684982022009186,2.1512615372917634,1.751667447018552,-1.4118743308181245,1.3959088234962316,0.2891251966313216,0.5805078633245453,-0.6777844648834328,0.9432286304255554,-1.2051532199617174,0.09011573382996567,0.4182557487269513,0.30380731745916084,-1.3068387009445777,0.6065201023101452,-1.4386772460322241,1.1358809033740525,0.6322515068949177,0.04192461851956566,0.8866106862369233,1.9386564503168657,1.6023224295792171,-0.04041324981336907,0.27435692511880505,2.1451816415421097,2.1451816415421097,-0.5948794930148794,2.0831876730587275,3.1003852237037637,-0.39751866108604983,0.3329162614491058 3193 Transport 193 483 3.0724786717927484 0.002122890032056 Q9BQE5,P24390,O60830,Q9UDW1,Q9H2D1,P61019,Q9NS69,Q9C0H2,P98194,Q8TEX9,Q8N4H5,O43676,Q9NX14,Q99595,O96008,O43169,O43731,O95197,O75306,O00461,Q96NB2,Q13505,O14949,Q9P2W9,Q00325,P06576,P21912,O43681,P55011,O75964,P45880,Q99720,P21796,Q9UGP8,P31751,Q9UBX3,Q14849,Q15758,Q96CU9,Q15363,Q12907,O60499,Q8N2H4,Q9H1E5,Q70HW3,O75431,O60826,Q9H936,Q9NR31,P24539,Q9Y5L4,Q8TAD4,Q9H9B4,Q9Y487,Q8TB61,O14925,Q9Y3B3,P22695,Q92973,Q5JRA6,P11166,O15127,P56134,Q9H0H5,Q9HD20,Q15629,O60784,Q9Y282,A6NIH7,Q96A65,Q3ZCQ8,Q9P0J0,Q13432,Q9Y277,O15504,Q02978,P52292,Q9H0U4,Q96ES6,Q9Y6C9,Q92621,Q7Z3C6,Q9BUN8,Q9NZJ7,Q7L0J3,P51970,Q03518,Q9H2V7,P11717,Q9BSK2,P08574,A0FGR8,Q6P4A7,P23786,P47985,Q9UJS0,Q96RL7,P08183,Q07955,P12236,Q9H2J7,Q9Y3A3,Q9Y6M7,O95202,O43772,P46459,P21281,P00403,P16615,Q9BQT8,Q9Y2T2,Q14203,Q93050,Q9HCU5,Q8NE86,P55060,Q9BUR5,Q15907,O15027,Q6DKK2,Q8WVM8,Q12981,Q969Q5,Q9BTX1,O95249,Q15388,Q96P70,Q15043,Q8IXU6,Q9Y3E0,Q13190,Q6P4Q7,P12235,O75381,Q9Y619,Q9H4A6,Q8N5M9,Q8NE01,P05141,P20020,Q9BPX6,P56385,P49755,Q9HC21,Q15904,Q9H3N1,P51572,Q99584,O75746,P46379,Q969E2,P05023,Q99808,Q9Y5X3,O43615,P51798,Q9UM00,A0AVF1,O75027,Q96S66,O95168,P53985,Q9BVK6,Q14728,P08195,Q6NUK1,Q9UNK0,P61026,Q99442,Q9BXP2,Q86Y82,P53007,P49257,O43808,Q12893,O15397,O15126,O14653,Q96FV9,Q8N1F7,Q12769,O95721,O14828,P28288,Q9Y5J9,Q8TDW0,Q6NUQ1,O95864,Q8NFH4,Q9Y3A6,Q9BVC6,P61916,O60831 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 1,2,5,6,7,520,10,11,522,528,15,16,530,19,525,25,26,27,543,34,546,36,37,39,554,552,553,557,558,47,48,50,51,571,564,57,58,565,60,61,574,63,69,75,77,583,582,593,594,83,602,86,601,88,89,92,95,97,616,613,612,106,618,627,113,114,623,119,120,636,639,129,134,135,642,644,138,664,142,143,661,660,147,148,149,656,152,155,669,162,668,666,166,167,679,169,178,176,699,179,705,185,189,190,191,694,693,195,196,197,714,710,208,726,724,721,213,216,715,219,734,223,226,227,229,232,237,241,246,250,253,254,259,263,267,268,279,280,284,291,301,305,304,319,323,329,327,336,350,351,358,363,372,373,376,383,385,394,397,403,404,407,415,411,417,419,429,430,432,433,442,440,447,444,456,453,463,462,478,477,474,472,470,473,488,484,483,482,494,498,495,491,489 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3193 Abnormal vertebral morphology 36 107 3.064527965766173 0.0021801379066512 Q9UM00,Q15125,P51798,O95831,Q14108,Q13045,Q9Y619,Q9UHX1,Q9UBM7,Q96L58,P51812,Q8WVQ1,Q32P28,Q6NUK1,P04062,Q9Y4P3,O95202,Q8NCH0,Q96HY6,Q8N3U4,Q96AY3,O60826,P04066,P16278,Q14739,P10644,O15228,P10619,P15586,Q6NUQ1,Q10713,Q9BV10,O75845,P16435,O96028,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 385,131,383,389,9,391,267,12,400,272,527,283,545,419,53,183,190,70,326,588,328,582,591,82,210,604,471,98,225,483,236,111,238,248,382,126 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3193 Nervous system process 33 102 3.0642682334376428 0.0021820317199401 O00264,P53611,Q13432,P50897,Q14108,Q9UQB8,P10253,P53634,P49419,O14773,Q7L576,O75915,P04062,P07196,O75844,O75592,P07686,P17900,P04035,Q92542,O60313,O60443,O75746,Q9Y5J9,Q99797,P05067,Q13641,Q99538,Q99808,O76024,P42345,Q05086,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 258,510,134,8,9,269,145,402,406,150,540,551,53,438,67,445,584,79,205,211,221,96,350,488,359,360,361,365,372,247,500,503,254 2985,258,2346,150,2905,221,96,2488,1706,2987,2489,445,1468,350,67,551,247,2307,205,53,2955,2654,360,1078,2282,438,584,145,1651,1306,79,2213,1825,2906,2138,1971,1525,1080,3023,500,2910,1081,1736,406,2523,2467,8,2217,510,402,2316,1744,2378,2409,2555,1605,503,1423,2836,2499,134,2265,361,9,1313,710,752,1288,2779,732,1774,254,2120,540,1112,1836,1811,647,2094,211,762,2594,1814,949,365,359,372,2786,1403,763,910,859,1146,1245,1820,2177,2299,269,1277,488,602,935 -1.2811099242588615,1.5017677751833673,-0.5342242617338631,1.945483805688231,-1.1066521830470757,1.6266810625618235,2.1932323689347277,-0.6360363435663436,-0.16014273539632354,-1.2811099242588615,-0.6360363435663436,0.9765264378161742,-0.023739075165896593,1.2064269794639189,2.329750012077,0.8167483885125356,1.5358542924197818,-0.51428752530657,1.7057429944746445,2.4355304023078563,-1.2051532199617174,-0.7848314137948916,1.1865067348823226,0.21440615544338357,-0.494489054305589,0.9875161701203701,0.7568588077238091,1.9658133945446885,-0.12538587769838372,0.07415070895816572,2.2457277457630314,-0.4553008972742839,-0.23102262249362931,-1.1066521830470757,-0.39751866108604983,-0.303787854117314,-0.05719278632694883,0.21440615544338357,-1.3589269339837995,0.9094287765563077,-1.1066521830470757,0.21440615544338357,-0.177690185818539,1.0629537868319574,-0.656835659642823,-0.6153848387722859,3.0232917146470886,-0.4553008972742839,0.8980485194817284,1.0735225288658525,-0.51428752530657,-0.177690185818539,-0.5543007948494578,-0.5745186791895069,-0.6777844648834328,-0.09107218097239303,0.9094287765563077,0.009297339019232754,-0.9877693062177954,-0.6360363435663436,2.0577643966472143,-0.4748273403029004,1.1865067348823226,3.0232917146470886,0.07415070895816572,0.5673949130081869,0.5142163574940924,0.09011573382996567,-0.9185947277776126,0.5409522516865753,-0.1953518618147444,1.5188836640650665,-0.3785188752723304,0.8519470898097677,0.19919490676105286,-0.23102262249362931,-0.213128942203161,0.6450133877649504,-0.3596472519831671,1.682361685022864,0.5007368375870117,-0.6988844633124501,-0.213128942203161,0.3184040786732402,1.176476578042439,1.1964900873490003,1.1663992693165688,-0.9185947277776126,0.02566161901174243,0.5007368375870117,0.34734463722339803,0.4042351666901161,0.1838925440088085,0.12175448251162654,-0.213128942203161,-0.41664798954862137,-0.494489054305589,1.4670922847773513,0.1059833465335269,0.9320183829658302,0.7324623353077244,0.3329162614491058 3193 Glycosaminoglycan metabolism 8 12 3.064046405170913 0.0021836503532139 P15586,Q7LGA3,P06865,Q8NCH0,O43505,P16278,Q8TB61,P54802 Processes and pathways Reactome Pathways msigdb_reactome 225,132,224,70,262,82,89,126 2396,262,224,584,225,82,126,132,70,89,272,2478 -0.5745186791895069,1.4845046522176364,1.6185951277994044,0.7568588077238091,1.6185951277994044,2.2399742438327923,2.095763221365341,2.070521741578072,2.302208489423922,2.2225958317358057,1.4583294958454196,-0.6153848387722859 3193 Regulated exocytosis 12 40 3.063534338412143 0.0021873909980874 P16615,P61026,Q99584,P09601,P11279,P49755,O43760,Q7L0J3,Q9BRK5,Q15907,O95721,O95295 Processes and pathways GO Biological process msigdb_gobp 196,430,336,17,206,304,78,149,151,216,472,409 2301,1383,2031,999,2905,2366,78,409,472,1730,1596,17,1306,206,196,1679,1598,2947,1018,304,1085,2080,2011,430,1605,1423,1424,2438,752,216,505,1234,1835,149,336,151,1148,1298,978,1277 -0.51428752530657,0.02566161901174243,-0.3409024311136362,0.27435692511880505,-1.1066521830470757,-0.5543007948494578,2.2457277457630314,1.05233382643295,0.9432286304255554,-0.177690185818539,-0.09107218097239303,2.850934877568107,0.07415070895816572,1.7057429944746445,1.751667447018552,-0.14270834812699967,-0.09107218097239303,-1.180235642836601,0.25950170179577764,1.3408498426869389,0.21440615544338357,-0.3596472519831671,-0.32228307221127694,1.0093338760985888,-0.09107218097239303,0.009297339019232754,0.009297339019232754,-0.5948794930148794,0.5142163574940924,1.6586937760640963,0.9094287765563077,0.12175448251162654,-0.23102262249362931,1.952285648216789,1.2457167051043052,1.945483805688231,0.1838925440088085,0.09011573382996567,0.30380731745916084,0.1059833465335269 3193 Abnormal retinal artery morphology 8 18 3.0584665232762944 0.0022247293443724 P10619,P06865,Q13510,P17900,P16278,Q9NZJ7,P07602,Q9Y4P3 Drugs and Diseases Human Phenotype Ontology msigdb_hp 98,224,45,79,82,148,20,183 1075,224,20,584,98,2676,82,79,288,2603,2604,2318,45,1771,2611,148,2067,183 0.21440615544338357,1.6185951277994044,2.762496989040066,0.7568588077238091,2.1872987787678158,-0.8067138905481915,2.2399742438327923,2.2457277457630314,1.4049437781239236,-0.7201373856155233,-0.7201373856155233,-0.51428752530657,2.5348046058833917,-0.1953518618147444,-0.7201373856155233,1.9590621281540601,-0.3409024311136362,1.7965090219596693 3193 Organophosphate ester transmembrane transporter activity 9 11 3.0571215536645897 0.0022347363337251 Q9BSK2,P12235,Q6NUK1,Q9H2D1,P12236,Q99808,Q8TB61,P05141,Q9HC21 Functions GO Molecular function msigdb_gomf 162,259,419,7,179,372,89,284,319 444,284,259,179,866,419,89,372,162,7,319 0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,0.39013449402256833,1.0416622545332883,2.2225958317358057,1.1663992693165688,1.8971479790749635,3.043830354362099,1.293823383957412 3193 Nucleotide transmembrane transporter activity 9 11 3.0571215536645897 0.0022347363337251 Q9BSK2,P12235,Q6NUK1,Q9H2D1,P12236,Q99808,Q8TB61,P05141,Q9HC21 Functions GO Molecular function msigdb_gomf 162,259,419,7,179,372,89,284,319 444,284,259,179,866,419,89,372,162,7,319 0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,0.39013449402256833,1.0416622545332883,2.2225958317358057,1.1663992693165688,1.8971479790749635,3.043830354362099,1.293823383957412 3193 Cellular homeostasis 56 141 3.0562495007724526 0.0022412467004278 Q96TC7,Q8N183,Q9UM00,P50897,P98194,O75880,O75503,O75027,P09601,P10253,P62942,Q7L0J3,Q8N5M9,O95295,Q16611,Q8N511,P20020,P06576,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9BXP2,P52789,Q9NQC3,Q9Y6M7,Q9UJZ1,O95202,Q16891,Q15904,P16615,P13473,P51572,P07686,O60826,Q93050,P02786,Q8TAD4,Q9Y487,Q15907,Q9BWH2,O00330,Q15120,Q92544,Q8WWC4,P05067,P05023,Q9HD20,Q15043,Q9HC07,Q99808,Q9Y263,O76024,Q05086,P62258 Processes and pathways GO Biological process msigdb_gobp 384,641,385,8,522,395,139,397,17,145,276,149,279,409,544,161,291,552,425,558,174,175,301,433,435,59,189,577,190,318,323,196,72,327,584,582,208,209,86,88,216,479,603,476,353,357,360,363,113,241,116,372,508,247,503,633 1383,1013,603,2541,916,2346,175,2488,582,397,139,395,3160,247,190,1647,409,2829,2637,209,3150,363,1676,360,1596,552,584,1387,2369,1200,17,796,2722,145,2917,72,2352,1443,2008,196,1623,2989,1501,2252,291,2288,2309,2906,3117,2185,2138,3030,3074,2930,3091,3055,2998,1081,2187,2039,8,890,924,327,3161,1799,435,1898,798,558,2551,1361,633,276,892,3119,2378,2409,2260,522,1605,503,2836,2992,1424,1393,2381,710,944,241,476,2779,323,216,544,2627,645,318,2797,149,2330,969,1137,425,641,161,279,724,86,357,353,208,174,1063,898,841,1724,384,372,301,858,479,433,813,801,2025,116,113,59,1247,2478,2151,577,385,508,3089,1277,88,677,2211,189 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3193 Abnormal form of the vertebral bodies 32 84 3.0449113961229277 0.0023274886769186 Q9UM00,Q15125,P51798,O95831,Q13045,Q9Y619,Q9UHX1,Q9UBM7,Q96L58,P51812,Q8WVQ1,Q32P28,Q6NUK1,Q9Y4P3,O95202,Q96HY6,Q8N3U4,Q96AY3,O60826,P04066,P16278,Q14739,P10644,O15228,P15586,Q6NUQ1,Q10713,Q9BV10,O75845,P16435,O96028,P54802 Drugs and Diseases Human Phenotype Ontology msigdb_hp 385,131,383,389,391,267,12,400,272,527,283,545,419,183,190,326,588,328,582,591,82,210,604,471,225,483,236,111,238,248,382,126 1279,2134,765,2303,471,3099,1554,1705,582,3029,238,2862,190,389,382,591,684,604,225,82,248,1652,693,3065,2620,1415,2184,2603,2549,1079,2465,2466,1180,3056,1159,383,527,126,2434,2934,2318,2410,1391,1534,236,964,391,2606,210,2047,1771,131,1289,2294,545,1657,613,419,483,2506,588,947,283,328,1041,326,1458,272,1486,111,3027,2061,2514,1376,400,12,2067,385,1463,1101,2719,183,267,1821 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3193 Lipid biosynthetic process 55 137 3.04354724353363 0.0023380672644479 O95470,Q15125,Q53H12,Q9H7Z7,Q9UKR5,Q16880,Q8WTV0,Q9UBM7,Q9HCL2,Q8NBX0,Q53GQ0,P35610,O00767,Q92604,Q9NPH0,Q14534,Q16850,Q86YN1,Q13510,P04062,Q8NF37,Q6UWP7,Q14849,Q8NCC3,Q8NBQ5,O75592,P49748,P30536,Q9P035,Q86UL3,P04035,Q92643,Q14739,Q15392,Q99805,O95674,O15228,P28288,Q9NTJ5,P37268,Q9BY49,O95864,Q15800,Q10713,Q9H490,Q06136,O75845,P05023,Q9UBF8,P35790,Q5T2R2,Q9BTU6,Q96G23,P16435,O15269 Processes and pathways GO Biological process msigdb_gobp 128,131,387,393,266,140,141,400,281,154,286,410,416,289,168,297,170,171,45,53,181,441,58,193,324,445,455,200,203,334,205,468,210,84,343,377,471,473,486,99,231,482,107,236,366,110,238,363,496,242,493,507,118,248,252 884,1278,864,2541,3169,416,766,471,252,1198,2905,1823,756,445,238,2862,1962,1015,128,1048,377,3139,482,2878,888,205,53,692,363,584,959,2403,2106,2460,2077,2957,3162,248,1623,3073,2309,1931,2704,2883,473,2521,200,1202,410,242,99,2793,500,2706,655,685,1084,455,2684,2948,750,3097,2981,1391,110,1092,236,3192,45,3120,868,297,210,58,131,2872,2502,84,1577,1939,788,107,645,170,140,1611,286,387,493,441,2817,334,171,1990,324,154,193,181,689,141,524,2818,289,468,1401,948,118,1322,663,1350,2839,343,507,3189,3182,2770,1192,231,1324,2149,366,393,281,168,2150,486,842,753,556,203,1493,496,400,2478,1589,266,2247 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3193 Metabolism of lipids 72 180 3.0309773644809206 0.0024376352141421 O95470,Q15125,Q53H12,P09960,Q9H7Z7,P50897,Q16880,Q8WVX9,Q9UBM7,P07602,Q9NZJ7,Q9HCL2,P38435,Q53GQ0,P35610,O00767,Q15165,Q92604,Q9NPJ6,Q9NQZ5,Q15067,P23786,Q9NZ01,P48163,Q9NPH0,Q16850,Q14534,O43681,Q13510,P04062,Q8NF37,Q6UWP7,Q8IV08,P53007,Q14849,Q9UMR5,O43772,Q8NCC3,O43808,Q8NBQ5,O75448,P49748,P51648,Q8NAN2,P30536,Q9P035,P17900,P04035,Q86UL3,Q96K12,P16278,Q14739,Q15392,O15228,Q9NTJ5,P10619,P37268,P06865,Q9BY49,O95864,Q15800,Q10713,Q99538,Q06136,O75845,Q9UBF8,P35790,P06280,Q9BTU6,Q96G23,O95674,O15269 Processes and pathways Reactome Pathways msigdb_reactome 128,131,387,264,393,8,140,524,400,20,148,281,157,286,410,416,33,289,547,163,420,167,556,41,168,170,297,557,45,53,181,441,184,440,58,188,191,193,444,324,454,455,71,457,200,203,79,205,334,469,82,210,84,471,486,98,99,224,231,482,107,236,365,110,238,496,242,244,507,118,377,252 666,667,884,1278,864,2541,3169,416,766,471,252,1198,2905,557,191,444,1555,1175,2002,454,2739,238,1647,128,2182,1521,1048,377,482,2878,205,53,3187,848,244,224,20,584,3146,264,98,3138,2077,2957,1258,3162,82,79,2287,1154,1679,1127,2309,1931,2704,167,2883,1601,200,1202,833,2705,410,242,3031,99,157,631,1226,2706,1052,41,655,685,1602,1084,455,923,8,71,850,440,2684,2948,2604,2218,1055,3114,3130,1625,2081,2981,1391,110,2436,1092,236,3192,45,3120,297,210,58,2196,2167,420,131,2872,33,2502,84,2294,1939,788,107,687,170,140,1611,286,387,441,334,2233,2837,184,1990,640,559,2838,2859,457,1432,324,193,181,689,524,2818,289,3042,118,469,1724,2769,365,1350,883,1026,507,3182,2770,1119,231,826,1324,2391,393,281,168,1846,547,163,486,842,753,556,148,203,1493,496,400,2341,2699,2343,188,1073,1194,629,979 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3193 Copii coated er to golgi transport vesicle 16 31 3.0281850653873543 0.0024602736852092 P49257,Q9UBR2,P05067,Q9Y3A6,P53634,P49755,P04439,Q9NR31,O14653,Q9Y282,Q13190,Q9BVK6,P10321,Q15363,Q9Y3B3,Q12907 Localization GO Cellular component msigdb_gocc 447,293,360,498,402,304,275,594,462,119,253,415,499,61,95,574 462,715,1961,2424,903,2651,2182,1521,1304,275,360,499,447,304,402,2604,2315,574,253,61,2294,1632,599,415,594,293,2894,119,498,95,1854 0.9543830980982788,0.5542099181825546,-0.303787854117314,-0.5948794930148794,0.34734463722339803,-0.7848314137948916,-0.43590826117893794,-0.05719278632694883,0.07415070895816572,1.4495286247621895,1.1865067348823226,0.9094287765563077,0.9765264378161742,1.3408498426869389,1.0735225288658525,-0.7201373856155233,-0.51428752530657,0.7810014179820873,1.5188836640650665,2.3514587661376916,-0.494489054305589,-0.1081741936250891,0.7324623353077244,1.05233382643295,0.7446925671515504,1.3959088234962316,-1.0585470825916556,2.1268132851345656,0.9207519138862322,2.1991455126433834,-0.23102262249362931 3193 Calcium ion binding 23 80 3.0171826157820782 0.0025513605951879 P80303,O43149,Q9BRK5,Q8WVQ1,Q02818,Q6NUK1,Q9Y680,Q9UJS0,Q8IYU8,Q96A33,Q9BPX6,Q8NF37,Q9NWM8,P27824,Q14257,O43852,O95202,P16615,Q96AY3,P55327,Q99584,O60476,O75746 Functions GO Molecular function msigdb_gomf 14,401,151,283,29,419,40,169,425,174,301,181,182,311,186,315,190,196,328,333,336,346,350 666,1104,401,557,1076,315,346,2424,445,350,794,190,692,1791,1522,2137,1387,1860,1764,2352,3164,1256,1443,1258,196,3073,1177,1501,1445,1598,2185,311,2907,3091,2898,1654,1052,1566,1528,333,2469,963,1089,14,1805,29,2836,1452,836,1428,186,681,2871,759,2169,419,2798,969,1137,425,181,283,174,328,993,336,883,301,151,1026,764,803,182,2065,2894,2478,169,622,1465,40 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3193 Synaptic vesicle membrane 8 16 3.0158283521482816 0.002562782919812 O60499,P20020,O43760,Q7L0J3,Q86Y82,Q15907,O76024,O95295 Localization GO Cellular component msigdb_gocc 63,291,78,149,442,216,247,409 1249,463,78,63,247,409,1677,291,1679,890,1130,771,216,149,442,2095 0.1059833465335269,0.9543830980982788,2.2457277457630314,2.346058243177083,1.5358542924197818,1.05233382643295,-0.14270834812699967,1.3959088234962316,-0.14270834812699967,0.36168996784734275,0.1838925440088085,0.48718206135466036,1.6586937760640963,1.952285648216789,0.9875161701203701,-0.3596472519831671 3193 Abnormality of head blood vessel 8 21 3.0091636291920385 0.0026196798398565 P10619,P06865,Q13510,P17900,P16278,Q9NZJ7,P07602,Q9Y4P3 Drugs and Diseases Human Phenotype Ontology msigdb_hp 98,224,45,79,82,148,20,183 2303,1075,224,20,584,98,2676,82,79,288,2603,685,2604,2318,45,1771,1987,2611,148,2067,183 -0.51428752530657,0.21440615544338357,1.6185951277994044,2.762496989040066,0.7568588077238091,2.1872987787678158,-0.8067138905481915,2.2399742438327923,2.2457277457630314,1.4049437781239236,-0.7201373856155233,0.5935493889180543,-0.7201373856155233,-0.51428752530657,2.5348046058833917,-0.1953518618147444,-0.303787854117314,-0.7201373856155233,1.9590621281540601,-0.3409024311136362,1.7965090219596693 3193 Delusions 6 21 3.0076055392986114 0.0026331467621867 Q9BQE5,Q9UJS0,Q96RL7,P07602,Q9NZJ7,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 1,169,178,20,148,53 765,557,53,20,1708,1258,288,2521,1032,1081,1711,2374,2015,2607,1142,178,1,1459,148,2537,169 0.48718206135466036,0.8048943132507087,2.4355304023078563,2.762496989040066,-0.16014273539632354,0.1059833465335269,1.4049437781239236,-0.656835659642823,0.2445587153188426,0.21440615544338357,-0.16014273539632354,-0.5543007948494578,-0.32228307221127694,-0.7201373856155233,0.1838925440088085,1.8112225085127378,3.268320628293502,-0.007169221259632773,1.9590621281540601,-0.656835659642823,1.854681789652418 3193 Chemical homeostasis 70 182 3.0014341509271225 0.0026871114955393 Q96TC7,Q9UM00,P50897,P42785,P98194,Q6IAA8,O75503,Q8WTV0,O75880,Q9Y6C9,Q5BJF2,P09601,O75027,P62942,Q7L0J3,Q8N5M9,Q8NE01,Q9HCL2,P53985,Q86YV9,P35610,O95295,P30519,Q16611,Q8N511,P20020,Q15067,P06576,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9BXP2,P52789,P04062,Q8NF37,Q9NQC3,Q9Y6M7,Q9UJZ1,O95202,Q16891,Q15904,P16615,P51572,P30536,P07686,Q9P035,Q93050,P02786,Q8TAD4,Q9Y487,Q15907,Q9BWH2,Q15120,Q92544,Q8WWC4,P05067,P05023,Q9HD20,Q15043,Q9HC07,Q99808,O15260,Q9Y5X3,O76024,P61916,Q05086,P49366,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 384,385,8,136,522,523,139,141,395,143,144,17,397,276,149,279,280,281,407,412,410,409,32,544,161,291,420,552,425,558,174,175,301,433,435,53,181,59,189,577,190,318,323,196,327,200,584,203,208,209,86,88,216,479,476,353,357,360,363,113,241,116,372,245,373,247,491,503,501,254 1383,1013,603,2541,1822,916,2346,2033,1621,245,175,2488,582,397,139,395,3160,247,2307,190,1647,409,2182,1763,209,53,2955,1730,363,1676,360,1596,552,1649,2282,584,1387,2369,1200,959,17,2428,2722,2917,2352,1443,2957,196,1623,1259,2491,2989,1966,1501,2252,291,2288,2309,2906,3117,2185,1600,2138,2831,32,200,3091,2705,410,2998,1973,1976,136,1081,2187,2039,501,8,890,924,327,3161,1799,435,407,798,558,1361,491,633,1867,276,892,2498,3119,2378,2260,522,1605,503,2887,2836,2992,1424,2499,3192,2265,2381,2412,944,2225,241,420,476,1288,2779,323,216,1682,544,645,318,144,1987,523,254,2797,149,412,2330,425,641,2838,161,279,1991,280,724,181,86,141,357,353,208,174,1063,898,841,1724,384,3151,372,301,479,433,2276,813,801,1146,2025,803,116,281,113,735,59,1883,1247,203,1461,2478,2151,577,1407,385,2647,88,677,373,2211,143,189 0.02566161901174243,0.25950170179577764,0.7201675789757652,-0.6777844648834328,-0.23102262249362931,0.3329162614491058,-0.5342242617338631,-0.3409024311136362,-0.1081741936250891,1.5442857407745552,1.8185362415383943,-0.6360363435663436,0.7568588077238091,1.0945079100252835,2.0123785518790727,1.1049253152266847,-2.361815391886055,1.5358542924197818,-0.51428752530657,1.7667329517528663,-0.12538587769838372,1.05233382643295,-0.43590826117893794,-0.1953518618147444,1.6979807301199143,2.4355304023078563,-1.2051532199617174,-0.177690185818539,1.176476578042439,-0.14270834812699967,1.1865067348823226,-0.09107218097239303,0.8167483885125356,-0.12538587769838372,-0.494489054305589,0.7568588077238091,0.02566161901174243,-0.5543007948494578,0.1374300649717309,0.30380731745916084,2.850934877568107,-0.5948794930148794,-0.8509667351664257,-1.1309875400384923,-0.5342242617338631,-0.007169221259632773,-1.2051532199617174,1.751667447018552,-0.1081741936250891,0.1059833465335269,-0.6360363435663436,-1.2811099242588615,-0.303787854117314,-0.04041324981336907,-0.4748273403029004,1.3959088234962316,-0.494489054305589,-0.51428752530657,-1.1066521830470757,-1.778616500027411,-0.43590826117893794,-0.09107218097239303,-0.39751866108604983,-0.9877693062177954,2.637217657100284,1.7364816398521126,-1.6042899045333228,-0.8287583635800084,1.05233382643295,-1.3068387009445777,-0.303787854117314,-0.303787854117314,2.0384546855538916,0.21440615544338357,-0.43590826117893794,-0.3409024311136362,0.9094287765563077,3.0232917146470886,0.36168996784734275,0.3329162614491058,1.2650915011001496,-2.3972018839891502,-0.213128942203161,0.9984518432806867,1.0629537868319574,0.45984406883424556,0.8048943132507087,0.04192461851956566,0.9207519138862322,0.6703324293561015,-0.24903411518852805,1.4495286247621895,0.36168996784734275,-0.6360363435663436,-1.8085693165877301,-0.5543007948494578,-0.4748273403029004,0.8866106862369233,-0.09107218097239303,0.9094287765563077,-1.0585470825916556,-0.9877693062177954,-1.2811099242588615,0.009297339019232754,-0.6360363435663436,-9.776177795607536,-0.4748273403029004,-0.5543007948494578,-0.5745186791895069,0.3184040786732402,-0.4553008972742839,1.5693674826960398,1.03093867386121,0.9432286304255554,0.09011573382996567,-0.9185947277776126,1.284289708677259,1.6586937760640963,-0.14270834812699967,0.8402742865808962,0.6450133877649504,1.293823383957412,1.9859173850366558,-0.303787854117314,0.8866106862369233,1.5188836640650665,-0.9414783391764264,1.952285648216789,1.05233382643295,-0.51428752530657,1.0201626829533696,0.6577068359941382,-0.9877693062177954,1.8971479790749635,1.4406894094750298,-0.303787854117314,1.4406894094750298,0.5542099181825546,1.7965090219596693,2.2342011612850494,1.9991966569128934,1.1964900873490003,1.2064269794639189,1.7057429944746445,1.825821535867474,0.22952714396117282,0.36168996784734275,0.4182557487269513,-0.16014273539632354,1.1358809033740525,-2.2236327840032746,1.1663992693165688,1.350128868152097,0.9432286304255554,1.0093338760985888,-0.4748273403029004,0.44605949669078204,0.45984406883424556,0.1838925440088085,-0.32228307221127694,0.45984406883424556,2.132957634741071,1.4406894094750298,2.1451816415421097,0.5409522516865753,2.3887739794503915,-0.24903411518852805,0.12175448251162654,1.7288431475403072,-0.007169221259632773,-0.6153848387722859,-0.39751866108604983,0.7810014179820873,0.02566161901174243,1.1358809033740525,-0.7631090610942425,2.2284083926639537,0.6194206088649225,1.1663992693165688,-0.43590826117893794,1.992569263975948,1.7742210599427393 3193 Snap receptor activity 9 15 2.999561801203152 0.0027036826785251 O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190,Q12981 Functions GO Molecular function msigdb_gomf 63,229,39,429,462,442,345,253,223 2301,462,345,782,63,903,229,472,1085,1424,223,253,442,39,429 -0.51428752530657,0.9543830980982788,1.216317751801572,0.4735513630461408,2.346058243177083,0.34734463722339803,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.6266810625618235,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696 3193 Snare interactions in vesicular transport 9 15 2.999561801203152 0.0027036826785251 O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190,Q12981 Processes and pathways KEGG Pathways msigdb_kegg 63,229,39,429,462,442,345,253,223 2301,462,345,782,63,903,229,472,1085,1424,223,253,442,39,429 -0.51428752530657,0.9543830980982788,1.216317751801572,0.4735513630461408,2.346058243177083,0.34734463722339803,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.6266810625618235,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696 3193 Hexosyltransferase activity 14 32 2.9882929243523786 0.002805405349699 Q6ZXV5,P06865,O43505,Q16880,P07686,P46977,P04843,Q9BV10,Q96L58,Q9BT22,Q8TCJ2,P04062,Q13126,Q2TAA5 Functions GO Molecular function msigdb_gomf 160,224,262,140,584,204,490,111,272,342,467,53,55,312 2134,2650,262,1705,756,2424,53,490,815,1649,224,584,1895,1861,1260,1035,204,1534,605,55,140,312,160,1136,1270,467,272,342,111,1045,997,3159 -0.39751866108604983,-0.7848314137948916,1.4845046522176364,-0.16014273539632354,0.5007368375870117,-0.5948794930148794,2.4355304023078563,0.9207519138862322,0.4321969562595515,-0.12538587769838372,1.6185951277994044,0.7568588077238091,-0.2671646500903092,-0.24903411518852805,0.1059833465335269,0.2445587153188426,1.7211740059471201,-0.05719278632694883,0.7201675789757652,2.4045094117547388,2.0123785518790727,1.3221664240422288,1.8971479790749635,0.1838925440088085,0.1059833465335269,0.9543830980982788,1.4583294958454196,1.2359622824697312,2.1512615372917634,0.2445587153188426,0.2891251966313216,-2.326770357792346 3193 Inorganic anion transport 19 27 2.984338129079811 0.0028419252640161 Q9Y277,Q9C0H2,Q96S66,Q00325,O43681,P55011,P45880,P08183,Q9BXP2,P21796,Q9UBX3,Q9Y6M7,P30536,Q9NW15,Q8TDW0,Q9UHG3,Q9H0H5,Q15043,P51798 Processes and pathways GO Biological process msigdb_gobp 135,11,403,554,557,558,48,176,433,51,57,189,200,220,484,105,627,241,383 3036,557,176,2722,51,200,833,48,3161,383,1898,558,554,644,241,3026,484,403,433,11,627,220,57,105,135,2211,189 -1.4118743308181245,0.8048943132507087,1.8112225085127378,-0.8509667351664257,2.5007588066882245,1.7364816398521126,0.4182557487269513,2.515439795372476,-2.3972018839891502,1.1358809033740525,-0.2671646500903092,0.8048943132507087,0.8167483885125356,0.6450133877649504,1.5693674826960398,-1.3589269339837995,0.9320183829658302,1.0735225288658525,1.0093338760985888,2.984818292512709,0.682890738977402,1.6427531946624607,2.39928112695771,2.175369810670554,2.051351117777622,-0.43590826117893794,1.7742210599427393 3193 SNARE protein 8 12 2.98348607056859 0.0028498500742666 O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190 Functions Panther Protein class panther_protein_class 63,229,39,429,462,442,345,253 2301,462,345,63,229,472,1085,1424,253,442,39,429 -0.51428752530657,0.9543830980982788,1.216317751801572,2.346058243177083,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696 3193 SNARE protein 8 12 2.98348607056859 0.0028498500742666 O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 63,229,39,429,462,442,345,253 2301,462,345,63,229,472,1085,1424,253,442,39,429 -0.51428752530657,0.9543830980982788,1.216317751801572,2.346058243177083,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696 3193 Ventricular hypertrophy 18 36 2.9766925193177323 0.0029137607741855 O43772,Q13724,P12235,Q6NUK1,P00403,O75844,P23786,P02545,O75880,P21912,O75431,P54098,Q9BV10,P10253,P06280,O75208,P40939,Q15233 Drugs and Diseases Human Phenotype Ontology msigdb_hp 191,511,259,419,195,67,167,643,395,553,583,686,111,145,244,563,631,673 1279,191,563,583,67,395,691,195,643,244,145,1651,259,1861,553,167,1795,1260,962,2657,631,2745,1035,686,2218,799,2412,511,673,419,1477,2767,947,841,111,1881 0.09011573382996567,1.7592151429408447,0.7929788244184839,0.7568588077238091,2.329750012077,1.1049253152266847,0.5805078633245453,1.751667447018552,0.6450133877649504,1.5526815978228736,1.9658133945446885,-0.12538587769838372,1.5017677751833673,-0.24903411518852805,0.8167483885125356,1.8618274754931423,-0.213128942203161,0.1059833465335269,0.30380731745916084,-0.7848314137948916,0.6703324293561015,-0.8733409382481655,0.2445587153188426,0.5935493889180543,-0.4553008972742839,0.45984406883424556,-0.5745186791895069,0.8980485194817284,0.6194206088649225,1.0416622545332883,-0.023739075165896593,-0.8958829370602809,0.3184040786732402,0.4182557487269513,2.1512615372917634,-0.24903411518852805 3193 Mitochondrial nucleotide transporter subfamily 8 9 2.9742909434919578 0.0029366648621371 Q9BSK2,P12235,Q6NUK1,Q9H2D1,Q70HW3,P12236,P05141,Q9HC21 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 162,259,419,7,77,179,284,319 444,284,259,179,419,77,162,7,319 0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,1.0416622545332883,2.2514617717609795,1.8971479790749635,3.043830354362099,1.293823383957412 3193 Rhog gtpase cycle 10 34 2.97384354700638 0.0029409498422758 P49257,P50402,Q6IAA8,Q86XL3,P02786,Q14739,O15173,P42167,Q13190,O95202 Processes and pathways Reactome Pathways msigdb_reactome 447,261,523,335,209,210,56,249,253,190 56,782,1557,190,1647,209,1078,2355,1417,249,447,261,890,1604,2163,1205,2358,2293,1231,253,1749,1428,210,1507,1317,523,540,733,335,1777,2534,1026,1587,1375 2.39928112695771,0.4735513630461408,-0.07407874008591195,1.7667329517528663,-0.12538587769838372,1.6979807301199143,0.21440615544338357,-0.5342242617338631,0.009297339019232754,1.5358542924197818,0.9765264378161742,1.4931547427369818,0.36168996784734275,-0.09107218097239303,-0.41664798954862137,0.1374300649717309,-0.5342242617338631,-0.494489054305589,0.12175448251162654,1.5188836640650665,-0.177690185818539,0.009297339019232754,1.6979807301199143,-0.04041324981336907,0.07415070895816572,0.8866106862369233,0.8519470898097677,0.5409522516865753,1.2457167051043052,-0.1953518618147444,-0.656835659642823,0.25950170179577764,-0.07407874008591195,0.04192461851956566 3193 Cytochrome complex assembly 8 13 2.9674457279094293 0.0030028529049686 Q15070,Q9BSK2,Q9Y2R0,O43819,Q7KZN9,Q69YU5,Q6DKK2,P53701 Processes and pathways GO Biological process msigdb_gobp 65,162,4,175,112,22,219,317 175,395,679,317,65,22,219,112,712,910,162,862,4 1.8185362415383943,1.1049253152266847,0.6065201023101452,1.3033138565109923,2.3406400045953175,2.745828206525584,1.6427531946624607,2.1451816415421097,0.5673949130081869,0.34734463722339803,1.8971479790749635,0.4042351666901161,3.129385678191442 3193 Mitochondrial carrier protein [IPR002067] 10 11 2.9486196754140908 0.0031919652617322 O75746,O43808,P12235,Q6NUK1,Q9BQT8,Q9UJS0,P12236,P53007,P05141,Q9HC21 Sequence InterPro Family interpro_family 350,444,259,419,197,169,179,440,284,319 444,350,284,259,179,440,419,197,593,319,169 0.9765264378161742,1.2064269794639189,1.4228948856937176,1.5017677751833673,1.803880161059405,0.9875161701203701,1.0416622545332883,1.751667447018552,0.7446925671515504,1.293823383957412,1.854681789652418 3193 Mitochondrial calcium ion transport 13 16 2.9410040499103265 0.003271502565127 Q99623,Q8WWC4,Q9Y277,Q10713,Q8IYU8,Q9BPX6,O95202,P45880,Q8NE86,P21796,Q9Y4W6,Q96TA2,Q9UJZ1 Processes and pathways Reactome Pathways msigdb_reactome 388,357,135,236,425,301,190,48,724,51,677,348,577 2072,190,51,786,48,236,425,724,357,1239,348,388,301,577,135,677 -0.3596472519831671,1.7667329517528663,2.5007588066882245,0.4735513630461408,2.515439795372476,1.5859138151123813,1.0201626829533696,0.5542099181825546,1.1964900873490003,0.12175448251162654,1.216317751801572,1.125611440557737,1.350128868152097,0.7810014179820873,2.051351117777622,0.6194206088649225 3193 Protein transporter activity 10 13 2.9329077856833674 0.0033580361385714 Q9Y5J9,O60830,Q15388,Q9NS69,Q9HD20,O96008,P49755,Q99595,Q9UGP8,O14925 Functions GO Molecular function msigdb_gomf 488,5,232,10,113,525,304,19,571,92 92,5,1152,525,304,941,232,647,19,113,10,571,488 2.2109109040904884,3.1165747016179965,0.1684982022009186,0.8751148153965543,1.3408498426869389,0.3184040786732402,1.6023224295792171,0.6450133877649504,2.8113998714497686,2.1451816415421097,3.0024397548003465,0.7929788244184839,0.9320183829658302 3193 Abnormality of the cerebrospinal fluid 52 137 2.928487510166881 0.0034061551708863 Q9P0J0,Q8N183,Q15125,P40855,O95831,O43505,Q9UBM7,Q9NX14,O43676,Q96L58,Q16625,P07602,Q6PI48,P51970,Q9NZJ7,P18074,O75306,P21964,Q6NUK1,P23786,Q03252,O43681,P55011,O43819,P07237,Q9NR77,P48651,P54098,P04062,Q96CU9,P53701,O95202,Q9HC21,P00403,Q8N3U4,O60826,Q9NPL8,Q15392,O43464,P20700,O00330,P10644,Q9Y5P6,O15360,P11166,Q9H490,Q10713,P13073,Q7KZN9,P16435,O96028,P51798 Drugs and Diseases Human Phenotype Ontology msigdb_hp 129,641,131,386,389,262,400,530,16,272,532,20,533,656,148,653,543,288,419,167,680,557,558,175,684,49,685,686,53,60,317,190,319,195,588,582,727,84,716,719,603,604,747,481,612,366,236,109,112,248,382,383 2540,603,2541,832,765,2303,481,885,716,262,16,557,175,1499,2001,582,876,543,1442,958,1557,2035,769,190,847,389,382,195,53,1356,684,20,2076,604,612,109,1258,248,653,3040,1224,719,3065,288,167,2372,2959,2493,1601,938,1795,1128,2549,2356,1079,2793,386,3012,1034,685,2582,1037,3049,2217,383,656,2112,317,2604,686,558,2113,1038,3130,1310,1570,1090,1362,2471,680,1092,2262,236,1342,964,2992,2606,2691,1287,2360,2749,131,84,1289,532,1002,1658,419,533,112,1477,1319,641,588,3175,1907,1368,2021,2611,2125,2126,744,1063,60,272,995,1909,2839,910,2242,1272,2861,1913,366,319,727,49,1168,1955,530,148,1848,129,400,2480,747,935 -0.6777844648834328,0.7201675789757652,-0.6777844648834328,0.4182557487269513,0.48718206135466036,-0.51428752530657,0.9320183829658302,0.36168996784734275,0.5542099181825546,1.4845046522176364,2.850934877568107,0.8048943132507087,1.8185362415383943,-0.04041324981336907,-0.32228307221127694,0.7568588077238091,0.3759530057373177,0.8402742865808962,-0.007169221259632773,0.30380731745916084,-0.07407874008591195,-0.3409024311136362,0.48718206135466036,1.7667329517528663,0.4042351666901161,1.1152930343193794,1.1358809033740525,1.751667447018552,2.4355304023078563,0.04192461851956566,0.5935493889180543,2.762496989040066,-0.3596472519831671,0.7201675789757652,0.7078077588474234,2.1512615372917634,0.1059833465335269,1.5358542924197818,0.6322515068949177,-1.4118743308181245,0.12175448251162654,0.5542099181825546,-1.492956015355766,1.4049437781239236,1.8618274754931423,-0.5543007948494578,-1.2051532199617174,-0.6360363435663436,-0.09107218097239303,0.3184040786732402,-0.213128942203161,0.1838925440088085,-0.6777844648834328,-0.5342242617338631,0.21440615544338357,-0.9414783391764264,1.125611440557737,-1.3327768033414031,0.2445587153188426,0.5935493889180543,-0.6988844633124501,0.2445587153188426,-1.4386772460322241,-0.4553008972742839,1.1358809033740525,0.6322515068949177,-0.3785188752723304,1.3033138565109923,-0.7201373856155233,0.5935493889180543,0.8048943132507087,-0.3785188752723304,0.2445587153188426,-1.9000405921739463,0.07415070895816572,-0.07407874008591195,0.21440615544338357,0.04192461851956566,-0.6153848387722859,0.6065201023101452,0.21440615544338357,-0.4748273403029004,1.5859138151123813,0.05808732403364699,0.30380731745916084,-1.2811099242588615,-0.7201373856155233,-0.8067138905481915,0.09011573382996567,-0.5342242617338631,-0.8733409382481655,2.070521741578072,2.2399742438327923,0.09011573382996567,0.863560440465855,0.27435692511880505,-0.12538587769838372,1.0416622545332883,0.863560440465855,2.1451816415421097,-0.023739075165896593,0.07415070895816572,0.6577068359941382,0.7568588077238091,-2.85051601606499,-0.2671646500903092,0.04192461851956566,-0.32228307221127694,-0.7201373856155233,-0.3785188752723304,-0.3785188752723304,0.5276212788728801,0.22952714396117282,2.356841664788679,1.4583294958454196,0.2891251966313216,-0.2671646500903092,-0.9877693062177954,0.34734463722339803,-0.4553008972742839,0.1059833465335269,-1.011180888611287,-0.2671646500903092,1.176476578042439,1.293823383957412,0.5542099181825546,2.515439795372476,0.1684982022009186,-0.28541547461577405,0.8751148153965543,1.9590621281540601,-0.23102262249362931,2.0831876730587275,1.0840404415884148,-0.6153848387722859,0.5276212788728801,0.3329162614491058 3193 Hormone metabolic process 14 32 2.9268695306998 0.0034239248239975 O95470,O75844,Q8NBQ5,Q9UBR2,P42892,P30536,Q9HB40,Q6NUM9,P05023,Q8TAD4,P16435,Q14849,Q53GQ0,Q8NBN7 Processes and pathways GO Biological process msigdb_gobp 128,67,324,293,100,200,42,207,363,86,248,58,286,287 1823,67,1962,128,363,959,2008,2957,248,200,100,3149,850,2887,58,1939,286,207,809,287,324,86,896,2818,898,2839,42,827,400,293,2877,531 -0.23102262249362931,2.329750012077,-0.303787854117314,2.0894866813375814,1.176476578042439,0.30380731745916084,-0.32228307221127694,-1.2051532199617174,1.5358542924197818,1.7364816398521126,2.181344630255124,-2.189902884432974,0.4042351666901161,-1.0585470825916556,2.394036011434074,-0.28541547461577405,1.413939040620315,1.7057429944746445,0.44605949669078204,1.413939040620315,1.284289708677259,2.2342011612850494,0.36168996784734275,-0.9645358333127365,0.36168996784734275,-0.9877693062177954,2.563411491546392,0.4321969562595515,1.0840404415884148,1.3959088234962316,-1.0347727466327314,0.8751148153965543 3193 Golgi apparatus subcompartment 39 92 2.917179920255911 0.0035321196331621 P98194,Q9H4A6,Q96L58,Q7Z3C6,P04439,Q8WVQ1,P11717,O00461,Q9UNK0,Q8TBA6,P61026,P04062,Q9Y3A3,Q15363,P46459,O60499,O14578,O75592,Q8N2H4,Q12893,P51572,O15126,Q16706,Q5VYK3,Q10471,Q8WVM8,O14828,Q4J6C6,O95249,Q969E2,P05067,O15127,Q10713,Q9NXE4,Q14789,Q9HC07,Q9BTU6,Q8IWJ2,Q96A57 Localization GO Cellular component msigdb_gocc 522,268,272,660,275,283,669,34,429,688,430,53,185,61,694,63,578,445,69,456,327,463,465,599,605,734,470,505,229,358,360,106,236,753,369,116,507,761,121 864,34,578,470,463,106,2366,1221,63,1705,1961,2105,445,229,2916,53,275,360,1677,2722,669,1155,3065,2309,2792,1033,694,1181,1203,327,1085,2111,2638,1038,2660,1979,430,1055,1746,522,2589,1391,2115,605,2116,236,1424,456,1807,868,369,2779,61,465,505,599,2296,660,822,761,69,688,947,734,283,1271,1480,1663,358,121,272,777,2362,2804,2786,507,1066,1616,268,2061,2714,116,2826,753,1070,1672,3183,429,1171,1673,185,1701 0.39013449402256833,2.605360668935537,0.7689615842364066,0.9432286304255554,0.9543830980982788,2.163357703140536,-0.5543007948494578,0.12175448251162654,2.346058243177083,-0.16014273539632354,-0.303787854117314,-0.3785188752723304,0.9765264378161742,1.6104756568747511,-1.1309875400384923,2.4355304023078563,1.4495286247621895,1.1865067348823226,-0.14270834812699967,-0.8509667351664257,0.6194206088649225,0.1684982022009186,-1.492956015355766,-0.51428752530657,-0.9414783391764264,0.2445587153188426,0.5805078633245453,0.15301100508827867,0.1374300649717309,1.2650915011001496,0.21440615544338357,-0.3785188752723304,-0.7631090610942425,0.2445587153188426,-0.7848314137948916,-0.303787854117314,1.0093338760985888,0.22952714396117282,-0.177690185818539,0.8866106862369233,-0.6988844633124501,0.02566161901174243,-0.3785188752723304,0.7201675789757652,-0.3785188752723304,1.5859138151123813,0.009297339019232754,0.9654822230844401,-0.213128942203161,0.39013449402256833,1.1663992693165688,-0.9185947277776126,2.3514587661376916,0.9543830980982788,0.9094287765563077,0.7324623353077244,-0.494489054305589,0.6322515068949177,0.4321969562595515,0.5007368375870117,2.31327983578579,0.5935493889180543,0.3184040786732402,0.5409522516865753,1.4318115854602973,0.1059833465335269,-0.023739075165896593,-0.12538587769838372,1.1964900873490003,2.1206472108366774,1.4583294958454196,0.48718206135466036,-0.5342242617338631,-0.9414783391764264,-0.9185947277776126,0.9094287765563077,0.22952714396117282,-0.09107218097239303,1.4670922847773513,-0.3409024311136362,-0.8287583635800084,2.132957634741071,-0.9645358333127365,0.5142163574940924,0.22952714396117282,-0.12538587769838372,-3.599840094441577,1.0201626829533696,0.1684982022009186,-0.12538587769838372,1.7891089124911725,-0.14270834812699967 3193 Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 13 32 2.916070715762398 0.0035447014891376 P30519,O00767,Q32P28,O75592,O95864,Q14534,Q16850,Q6UW02,Q15800,O75845,P09601,P13674,P16435 Functions GO Molecular function msigdb_gomf 32,416,545,445,482,297,170,74,107,238,17,464,248 2134,416,1123,2000,1705,445,238,482,684,17,464,248,32,1975,2585,1534,1452,297,107,170,545,2088,1661,74,2766,2020,615,1043,2861,873,2394,1887 -0.39751866108604983,1.0416622545332883,0.1838925440088085,-0.32228307221127694,-0.16014273539632354,0.9765264378161742,1.5776579775269348,0.9320183829658302,0.5935493889180543,2.850934877568107,0.9543830980982788,1.5358542924197818,2.637217657100284,-0.303787854117314,-0.6988844633124501,-0.05719278632694883,-0.007169221259632773,1.38683389940539,2.163357703140536,1.8475085220023033,0.8402742865808962,-0.3596472519831671,-0.12538587769838372,2.2685480296028047,-0.8958829370602809,-0.32228307221127694,0.7078077588474234,0.2445587153188426,-1.011180888611287,0.39013449402256833,-0.5543007948494578,-0.24903411518852805 3193 Abnormal chorioretinal morphology 13 27 2.9156865104091865 0.0035490690811661 Q8IY17,P40855,Q5XKP0,P52732,O75381,O43505,Q9Y619,Q10713,O60826,Q9NX14,P04439,P53701,P40939 Drugs and Diseases Human Phenotype Ontology msigdb_hp 640,386,260,509,263,262,267,236,582,530,275,317,631 999,262,1704,582,263,1468,2654,275,1128,386,631,1527,509,317,2375,1090,1391,236,964,260,2730,640,1063,649,530,267,1821 0.27435692511880505,1.4845046522176364,-0.16014273539632354,0.7568588077238091,1.4845046522176364,-0.023739075165896593,-0.7848314137948916,1.4495286247621895,0.1838925440088085,1.125611440557737,0.6703324293561015,-0.05719278632694883,0.8980485194817284,1.3033138565109923,-0.5543007948494578,0.21440615544338357,0.02566161901174243,1.5859138151123813,0.30380731745916084,1.5017677751833673,-0.8509667351664257,0.6577068359941382,0.22952714396117282,0.6450133877649504,0.8751148153965543,1.4758172511688186,-0.213128942203161 3193 Abnormal choroid morphology 13 27 2.9156865104091865 0.0035490690811661 Q8IY17,P40855,Q5XKP0,P52732,O75381,O43505,Q9Y619,Q10713,O60826,Q9NX14,P04439,P53701,P40939 Drugs and Diseases Human Phenotype Ontology msigdb_hp 640,386,260,509,263,262,267,236,582,530,275,317,631 999,262,1704,582,263,1468,2654,275,1128,386,631,1527,509,317,2375,1090,1391,236,964,260,2730,640,1063,649,530,267,1821 0.27435692511880505,1.4845046522176364,-0.16014273539632354,0.7568588077238091,1.4845046522176364,-0.023739075165896593,-0.7848314137948916,1.4495286247621895,0.1838925440088085,1.125611440557737,0.6703324293561015,-0.05719278632694883,0.8980485194817284,1.3033138565109923,-0.5543007948494578,0.21440615544338357,0.02566161901174243,1.5859138151123813,0.30380731745916084,1.5017677751833673,-0.8509667351664257,0.6577068359941382,0.22952714396117282,0.6450133877649504,0.8751148153965543,1.4758172511688186,-0.213128942203161 3193 Retrograde vesicle mediated transport golgi to endoplasmic reticulum 10 28 2.9155804190165413 0.0035502759754084 P24390,O15258,Q9P2W9,Q12893,Q6NUQ1,Q9H4A6,P49755,Q9Y282,O43731,Q12981 Processes and pathways GO Biological process msigdb_gobp 2,355,39,456,483,268,304,119,26,223 844,2486,355,26,903,2213,2,1156,1081,1053,1602,304,2659,1390,1746,1057,456,574,223,483,871,734,1480,268,2061,39,2101,119 0.4042351666901161,-0.6360363435663436,1.1964900873490003,2.6816050945494077,0.34734463722339803,-0.4553008972742839,3.21572160468917,0.1684982022009186,0.21440615544338357,0.22952714396117282,-0.09107218097239303,1.3408498426869389,-0.7848314137948916,0.02566161901174243,-0.177690185818539,0.22952714396117282,0.9654822230844401,0.7810014179820873,1.6266810625618235,0.9320183829658302,0.39013449402256833,0.5409522516865753,-0.023739075165896593,1.4670922847773513,-0.3409024311136362,2.572831939044648,-0.3596472519831671,2.1268132851345656 3193 Abnormal vascular physiology 13 47 2.9086743225118736 0.0036296475620247 Q6NUK1,P00403,O75844,P51798,P05067,Q14108,Q14739,P06280,P04062,Q9NWM8,Q9Y4P3,Q8IZA0,Q9NZ08 Drugs and Diseases Human Phenotype Ontology msigdb_hp 419,195,67,383,360,9,210,244,53,182,183,93,159 864,1123,1705,1789,2035,67,1520,195,1304,643,53,1356,360,244,1651,1652,981,3065,1333,2185,2760,1128,2603,1976,1084,383,656,2113,2318,1534,1092,9,2748,210,1771,493,419,93,947,1063,2206,182,159,2067,2480,183,1821 0.39013449402256833,0.1838925440088085,-0.16014273539632354,-0.213128942203161,-0.3409024311136362,2.329750012077,-0.05719278632694883,1.751667447018552,0.07415070895816572,0.6450133877649504,2.4355304023078563,0.04192461851956566,1.1865067348823226,1.5526815978228736,-0.12538587769838372,-0.12538587769838372,0.2891251966313216,-1.492956015355766,0.05808732403364699,-0.43590826117893794,-0.8958829370602809,0.1838925440088085,-0.7201373856155233,-0.303787854117314,0.21440615544338357,1.1358809033740525,0.6322515068949177,-0.3785188752723304,-0.51428752530657,-0.05719278632694883,0.21440615544338357,3.0232917146470886,-0.8733409382481655,1.6979807301199143,-0.1953518618147444,0.9207519138862322,1.0416622545332883,2.205038320950641,0.3184040786732402,0.22952714396117282,-0.43590826117893794,1.7965090219596693,1.9041316359550924,-0.3409024311136362,-0.6153848387722859,1.7965090219596693,-0.213128942203161 3193 Endomembrane system organization 63 167 2.9052654128869784 0.0036694179697012 Q96MW5,P50402,P61019,Q14108,P02545,Q6IAA8,O14964,Q9H4A6,Q9UQB8,Q8NHH9,Q7Z3C6,Q8N5M9,Q9BVK6,O95197,Q96GC9,O95295,A0FGR8,Q5J8M3,Q9P2W9,O43681,Q8TBA6,Q96A33,P61026,Q00765,P49755,P31751,Q9NQC3,Q15363,Q12907,P46459,P49257,O14578,O75844,O94901,P16615,Q14203,Q9BTV4,Q86XL3,O43760,O75955,O15027,P20700,Q8N1F7,O95721,Q9Y3B3,Q12981,P46379,Q9Y371,Q5JRA6,Q9Y3A6,Q9UH99,Q15042,Q9NXE4,Q9NPA0,Q14789,Q15629,Q8NFQ8,O15260,Q9BTU6,Q8IWJ2,P62820,Q13190,P57088 Processes and pathways GO Biological process msigdb_gobp 777,261,520,9,643,523,767,268,269,271,660,279,415,27,156,409,666,550,39,557,688,174,430,431,304,564,59,61,574,694,447,578,67,690,196,710,460,335,78,338,715,719,477,472,95,223,351,487,613,498,497,752,753,239,369,114,626,245,507,761,758,253,255 666,1889,2301,2302,1249,578,916,1646,2346,767,1331,715,245,2542,2905,557,78,919,2104,1961,2105,2348,903,1789,1047,67,338,690,2651,27,1647,409,472,643,1596,785,1387,196,2581,719,2309,2906,2138,564,1018,2356,1033,1180,866,1081,1736,351,694,940,447,304,261,1181,890,3161,1109,1086,255,2163,520,1130,430,941,758,2041,818,1746,431,1090,2471,964,1424,574,2499,223,2626,253,9,710,369,893,752,1505,1288,61,114,550,613,1161,523,2913,2504,660,1236,968,335,761,1345,477,279,909,989,1061,626,271,2273,688,947,2055,2333,1480,2938,1663,1062,1880,174,1064,156,777,3126,2804,2786,1026,507,460,415,1881,930,268,1845,2338,932,2061,1952,2875,860,239,59,1148,753,2674,1170,1493,1298,39,497,1070,1958,1462,2716,1699,1959,1276,1171,269,998,2030,487,498,95,1701,1854 0.6194206088649225,-0.2671646500903092,-0.51428752530657,-0.51428752530657,0.1059833465335269,0.7689615842364066,0.3329162614491058,-0.12538587769838372,-0.5342242617338631,0.48718206135466036,0.05808732403364699,0.5542099181825546,1.5442857407745552,-0.6777844648834328,-1.1066521830470757,0.8048943132507087,2.2457277457630314,0.3329162614491058,-0.3785188752723304,-0.303787854117314,-0.3785188752723304,-0.5342242617338631,0.34734463722339803,-0.213128942203161,0.22952714396117282,2.329750012077,1.2359622824697312,0.5805078633245453,-0.7848314137948916,2.6684245539590274,-0.12538587769838372,1.05233382643295,0.9432286304255554,0.6450133877649504,-0.09107218097239303,0.4735513630461408,0.02566161901174243,1.751667447018552,-0.6988844633124501,0.5542099181825546,-0.51428752530657,-1.1066521830470757,-0.39751866108604983,0.7929788244184839,0.25950170179577764,-0.5342242617338631,0.2445587153188426,0.15301100508827867,0.39013449402256833,0.21440615544338357,-0.177690185818539,1.2064269794639189,0.5805078633245453,0.3184040786732402,0.9765264378161742,1.3408498426869389,1.4931547427369818,0.15301100508827867,0.36168996784734275,-2.3972018839891502,0.19919490676105286,0.21440615544338357,1.510343999684222,-0.41664798954862137,0.8866106862369233,0.1838925440088085,1.0093338760985888,0.3184040786732402,0.5007368375870117,-0.3409024311136362,0.4321969562595515,-0.177690185818539,1.0093338760985888,0.21440615544338357,-0.6153848387722859,0.30380731745916084,0.009297339019232754,0.7810014179820873,-0.6360363435663436,1.6266810625618235,-0.7415449896710221,1.5188836640650665,3.0232917146470886,0.5673949130081869,1.1663992693165688,0.36168996784734275,0.5142163574940924,-0.04041324981336907,0.09011573382996567,2.3514587661376916,2.1390803803002107,0.8285415486462114,0.7078077588474234,0.1684982022009186,0.8866106862369233,-1.1066521830470757,-0.6360363435663436,0.6322515068949177,0.12175448251162654,0.30380731745916084,1.2457167051043052,0.5007368375870117,0.05808732403364699,0.9432286304255554,1.4406894094750298,0.34734463722339803,0.2891251966313216,0.22952714396117282,0.682890738977402,1.4583294958454196,-0.4748273403029004,0.5935493889180543,0.3184040786732402,-0.3409024311136362,-0.51428752530657,-0.023739075165896593,-1.1555145615983378,-0.12538587769838372,0.22952714396117282,-0.24903411518852805,1.825821535867474,0.22952714396117282,1.9180197862656285,0.48718206135466036,-1.8692775678719071,-0.9414783391764264,-0.9185947277776126,0.25950170179577764,0.9094287765563077,0.9654822230844401,1.05233382643295,-0.24903411518852805,0.3329162614491058,1.4670922847773513,-0.23102262249362931,-0.51428752530657,0.3329162614491058,-0.3409024311136362,-0.28541547461577405,-1.0347727466327314,0.4042351666901161,1.5776579775269348,2.3887739794503915,0.1838925440088085,0.5142163574940924,-0.7848314137948916,0.1684982022009186,-0.023739075165896593,0.09011573382996567,2.572831939044648,0.9207519138862322,0.22952714396117282,-0.28541547461577405,-0.007169221259632773,-0.8287583635800084,-0.14270834812699967,-0.28541547461577405,0.1059833465335269,0.1684982022009186,1.4670922847773513,0.2891251966313216,-0.32228307221127694,0.9320183829658302,0.9207519138862322,2.1991455126433834,-0.14270834812699967,-0.23102262249362931 3193 Basolateral plasma membrane 17 42 2.903721153675505 0.0036875643003015 Q14254,P08195,P35613,P20020,P11166,P55011,P05023,P02786,Q15043,Q9Y6M7,O75955,Q99808,P53985,Q12959,Q6P4Q7,P78310,P57105 Localization GO Cellular component msigdb_gocc 671,417,192,291,612,558,363,209,241,189,338,372,407,625,254,536,222 1383,999,338,1254,209,692,363,1676,1522,417,1559,612,1792,2008,1524,2284,1177,291,1827,833,1128,192,866,407,798,558,222,1568,536,1091,1424,2499,625,2438,1313,671,241,254,2534,372,189,2773 0.02566161901174243,0.27435692511880505,1.2359622824697312,0.1059833465335269,1.6979807301199143,0.5805078633245453,1.176476578042439,-0.14270834812699967,-0.05719278632694883,1.0416622545332883,-0.07407874008591195,0.7078077588474234,-0.213128942203161,-0.32228307221127694,-0.05719278632694883,-0.494489054305589,0.15301100508827867,1.3959088234962316,-0.23102262249362931,0.4182557487269513,0.1838925440088085,1.7592151429408447,0.39013449402256833,1.0629537868319574,0.45984406883424556,0.8048943132507087,1.6266810625618235,-0.07407874008591195,0.8519470898097677,0.21440615544338357,0.009297339019232754,-0.6360363435663436,0.682890738977402,-0.5948794930148794,0.07415070895816572,0.6194206088649225,1.5693674826960398,1.5188836640650665,-0.656835659642823,1.1663992693165688,1.7742210599427393,-0.8958829370602809 3193 Calcium ion transport 19 52 2.900454171694898 0.0037262232166519 Q9UM00,P98194,P62942,Q96GC9,Q16611,P08195,P20020,Q8IYU8,Q9BPX6,P21796,O95202,Q9UJZ1,O75844,P16615,P30536,Q8WWC4,Q9HC07,O76024,P62258 Processes and pathways GO Biological process msigdb_gobp 385,522,276,156,544,417,291,425,301,51,190,577,67,196,200,357,116,247,633 1249,999,2488,1222,2072,67,247,190,1730,1676,1596,1522,1387,417,1792,2403,2352,196,1623,1501,291,51,3117,200,3091,1128,1081,1089,941,633,276,2378,522,1605,1423,2836,2193,1425,2381,544,2330,425,724,357,1400,156,898,301,116,577,385,677 0.1059833465335269,0.27435692511880505,-0.6360363435663436,0.12175448251162654,-0.3596472519831671,2.329750012077,1.5358542924197818,1.7667329517528663,-0.177690185818539,-0.14270834812699967,-0.09107218097239303,-0.05719278632694883,0.02566161901174243,1.0416622545332883,-0.213128942203161,-0.5745186791895069,-0.5342242617338631,1.751667447018552,-0.1081741936250891,-0.04041324981336907,1.3959088234962316,2.5007588066882245,-1.778616500027411,1.7364816398521126,-1.6042899045333228,0.1838925440088085,0.21440615544338357,0.21440615544338357,0.3184040786732402,0.6703324293561015,1.4495286247621895,-0.5543007948494578,0.8866106862369233,-0.09107218097239303,0.009297339019232754,-0.9877693062177954,-0.43590826117893794,0.009297339019232754,-0.5543007948494578,0.8402742865808962,-0.51428752530657,1.0201626829533696,0.5542099181825546,1.1964900873490003,0.02566161901174243,1.9180197862656285,0.36168996784734275,1.350128868152097,2.132957634741071,0.7810014179820873,1.1358809033740525,0.6194206088649225 3193 Monovalent inorganic cation homeostasis 15 29 2.8923550862118006 0.0038236552836488 Q8N511,Q15904,P50897,P06576,O75503,Q93050,P05023,Q9BXP2,Q9HC07,Q9Y5X3,Q9Y487,Q05086,Q9Y6M7,Q92544,O95295 Processes and pathways GO Biological process msigdb_gobp 161,323,8,552,139,208,363,433,116,373,88,503,189,353,409 139,409,1730,363,1676,552,2722,2906,2138,8,890,3161,798,558,1361,503,323,161,353,208,1063,433,116,2478,2151,88,373,2211,189 2.0123785518790727,1.05233382643295,-0.177690185818539,1.176476578042439,-0.14270834812699967,0.8167483885125356,-0.8509667351664257,-1.1066521830470757,-0.39751866108604983,3.0232917146470886,0.36168996784734275,-2.3972018839891502,0.45984406883424556,0.8048943132507087,0.04192461851956566,0.9094287765563077,1.284289708677259,1.8971479790749635,1.2064269794639189,1.7057429944746445,0.22952714396117282,1.0093338760985888,2.132957634741071,-0.6153848387722859,-0.39751866108604983,2.2284083926639537,1.1663992693165688,-0.43590826117893794,1.7742210599427393 3193 Amino acid transmembrane transport 11 13 2.8890998303364843 0.0038634639819161 O75746,P08195,Q96NB2,Q8TDW0,Q9UJS0,Q9Y619,O75915,Q9H936,O60831,Q9H9B4,Q15758 Processes and pathways GO Biological process msigdb_gobp 350,417,546,484,169,267,551,593,489,601,565 489,350,551,1078,417,565,484,546,705,593,601,169,267 0.9207519138862322,1.2064269794639189,0.8167483885125356,0.21440615544338357,1.0416622545332883,0.7929788244184839,0.9320183829658302,0.8402742865808962,0.5805078633245453,0.7446925671515504,0.7324623353077244,1.854681789652418,1.4758172511688186 3193