term	overlap	setsize	score	pval	edge	type	subtype	subtype_key	edge_idxs	ann_idxs	ann_vals	sig_size
Lysosome	27	56	3.9030371457612434	9.499311704441736e-05	Q14108,O15118,P10253,O14773,P54802,O75503,Q8NCC3,P06280,P16278,P11717,P20645,Q9Y487,P15586,Q8NHS3,P10619,O00754,P07602,P50897,Q9UMR5,Q93050,P08236,P04066,Q15012,P61916,Q99523,P11117,O43681	Processes and pathways	KEGG Pathways	msigdb_kegg	255,252,266,391,147,24,28,153,155,154,37,43,410,52,59,435,69,72,77,82,455,228,353,351,114,236,118	2321,1952,435,2792,391,252,118,2860,24,703,228,153,1013,69,3538,455,1702,1703,266,59,236,1082,154,2332,410,155,2869,37,707,3578,72,1632,147,2768,2587,351,3571,952,1160,3473,255,353,965,28,52,2014,82,114,520,1933,1064,2401,3008,77,1436,43	-0.2609563355332265,-0.13054795621506413,0.7224199472328477,-0.4920008457387619,0.7838890695289682,1.08805639508316,1.7982903969638317,-0.525313577596298,4.11230346222967,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,0.6916031594494587,-0.03347806686168351,-0.03347806686168351,1.0578712931665288,2.5402599154147643,1.1482768495977804,0.2224334357534765,1.5350292358486646,-0.2609563355332265,0.7531817696547146,1.5350292358486646,-0.525313577596298,3.284999162596966,0.44303477605405855,-1.63783022894056,2.399583395405736,-0.0012581004565036626,1.5644560394229112,-0.4587663248239629,-0.3595238272390506,0.8756881681175116,-1.5654960467228805,0.2857692407025649,0.19067127264620573,-1.174345720866778,1.08805639508316,0.8756881681175116,0.2857692407025649,3.768713037747525,2.818941470146897,-0.13054795621506413,2.2010744460285183,1.8563207862044178,0.6298028841948623,-0.098122333905974,0.25413257026133235,-0.2609563355332265,-0.5921770650124923,2.314734830304036,0.09500082791205905,3.2306497156014906	3643
SLC superfamily of solute carriers	28	55	3.72324084081255	0.0001966817388834	Q9BSK2,Q86VD7,Q9HC07,Q96H78,Q6NT16,Q8IXU6,O43772,Q01650,Q7L0J3,Q9HC21,Q9Y619,Q9Y666,Q9Y6C9,Q8N1S5,P11166,O00400,Q70HW3,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P41440,Q9Y6M7	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	260,256,405,274,10,12,13,143,17,553,693,694,695,671,279,646,285,152,306,577,44,573,662,54,440,733,90,361	646,13,2754,1450,1372,152,1962,1873,704,279,2331,1145,54,90,2073,44,440,2812,143,2771,963,662,2274,1657,10,2366,3456,285,17,256,12,671,3525,573,1502,274,2906,2907,2292,577,260,2115,733,1350,1057,405,553,1064,306,924,2788,693,694,695,361	0.47430803058067816,5.243267115697605,-0.4587663248239629,0.06298071889501843,0.09500082791205905,1.5350292358486646,-0.13054795621506413,-0.098122333905974,0.44303477605405855,1.027635769907882,-0.2609563355332265,0.19067127264620573,2.707887319665007,2.058127752852981,-0.16304347134508207,3.1215736355280526,0.7224199472328477,-0.4920008457387619,1.5938382520831849,-0.4587663248239629,0.2857692407025649,0.47430803058067816,-0.22824695247054547,-0.0012581004565036626,5.593769792208002,-0.2609563355332265,-1.1393655482262741,1.027635769907882,4.734981990697083,1.08805639508316,5.444068869967951,0.47430803058067816,-1.315246174406957,0.5677772700633923,0.06298071889501843,1.0578712931665288,-0.525313577596298,-0.525313577596298,-0.22824695247054547,0.5677772700633923,1.08805639508316,-0.16304347134508207,0.44303477605405855,0.12695555655645674,0.25413257026133235,0.7838890695289682,0.5988184783374502,0.25413257026133235,0.9973494401983068,0.31734400267200297,-0.4587663248239629,0.47430803058067816,0.47430803058067816,0.47430803058067816,0.8756881681175116	3643
Vacuolar membrane	34	147	3.565765142284264	0.0003627961616063	Q14108,P42785,O15118,Q8WTV0,Q9HD42,P30511,Q01650,P10253,O75503,Q8TCT8,P20645,Q9UIQ6,Q9Y487,Q07065,O75787,O14678,Q9BXS4,Q8NHS3,P42892,Q92542,P10619,P07602,Q8IV08,P55735,Q93050,P41440,Q9NRA0,O15260,Q99523,P15291,P11117,O75955,Q9NQX7,Q9NUN5	Localization	GO Cellular component	msigdb_gocc	255,4,252,8,276,138,143,266,24,158,37,42,43,173,296,176,50,52,53,317,59,69,73,201,82,90,227,108,114,112,236,249,122,123	1952,2792,176,252,108,586,2963,2860,1138,2700,1078,24,296,249,2798,1456,2507,2328,3617,703,3104,3191,69,3106,704,1457,2057,1702,266,59,3219,236,2144,1082,2332,112,37,2061,3422,2927,563,2580,138,2873,312,1624,2661,3200,90,1086,4,53,1628,1300,2156,459,3607,460,476,2348,201,2768,2717,2586,2075,2587,3571,2251,1636,952,143,622,173,2772,1160,898,255,3301,353,963,854,541,2001,3126,479,73,1177,466,1914,1180,1916,52,158,8,3356,2099,317,82,2180,1050,679,574,2624,1675,114,864,3179,1929,3642,50,1933,3237,1423,2115,1349,1936,1350,2391,2303,405,1844,276,1193,122,227,123,2912,3337,1850,1064,739,1199,2633,1944,2401,42,1595,2309,2127,1690,1599,1436,3493,1437,43,1280,877	-0.13054795621506413,-0.4920008457387619,1.446478167816503,1.08805639508316,1.914184390727662,0.5366787829519797,-0.5921770650124923,-0.525313577596298,0.19067127264620573,-0.42560918711049844,0.2224334357534765,4.11230346222967,0.9973494401983068,1.118191455601226,-0.4920008457387619,0.06298071889501843,-0.3265940252928932,-0.2609563355332265,-2.342454069604444,0.44303477605405855,-0.6930805097254553,-0.7607655898218467,2.427791890653298,-0.6930805097254553,0.44303477605405855,0.06298071889501843,-0.16304347134508207,-0.03347806686168351,1.0578712931665288,2.5402599154147643,-0.7947358122572576,1.1482768495977804,-0.19560956934146895,0.2224334357534765,-0.2609563355332265,1.8563207862044178,3.284999162596966,-0.16304347134508207,-1.069696640684267,-0.5587053640309138,0.5677772700633923,-0.3595238272390506,1.623176179314646,-0.525313577596298,0.9670119136618348,-0.0012581004565036626,-0.3925286203228279,-0.7607655898218467,2.058127752852981,0.2224334357534765,6.233993929662534,2.763483088965262,-0.0012581004565036626,0.12695555655645674,-0.19560956934146895,0.6916031594494587,-2.042021033479733,0.6916031594494587,0.6607309570482511,-0.2609563355332265,1.327766595224347,-0.4587663248239629,-0.42560918711049844,-0.3595238272390506,-0.16304347134508207,-0.3595238272390506,-1.5654960467228805,-0.22824695247054547,-0.0012581004565036626,0.2857692407025649,1.5938382520831849,0.5055225334229401,1.4760406150941263,-0.4587663248239629,0.19067127264620573,0.31734400267200297,1.08805639508316,-0.8629365633590367,0.8756881681175116,0.2857692407025649,0.34885740302862467,0.5988184783374502,-0.13054795621506413,-0.6930805097254553,0.6607309570482511,2.399583395405736,0.19067127264620573,0.6916031594494587,-0.098122333905974,0.19067127264620573,-0.098122333905974,2.818941470146897,1.5350292358486646,5.940175937290734,-0.931491220478586,-0.16304347134508207,0.9670119136618348,2.2010744460285183,-0.19560956934146895,0.25413257026133235,0.47430803058067816,0.5677772700633923,-0.3595238272390506,-0.0012581004565036626,1.8563207862044178,0.34885740302862467,-0.726880811724572,-0.098122333905974,-14.964006912322265,2.901874777421383,-0.098122333905974,-0.7947358122572576,0.09500082791205905,-0.16304347134508207,0.12695555655645674,-0.098122333905974,0.12695555655645674,-0.2609563355332265,-0.22824695247054547,0.7838890695289682,-0.06576592628969985,1.0578712931665288,0.19067127264620573,1.7692119702003737,1.2083001127798034,1.7692119702003737,-0.525313577596298,-0.8971691305719629,-0.06576592628969985,0.25413257026133235,0.44303477605405855,0.19067127264620573,-0.3595238272390506,-0.098122333905974,-0.2609563355332265,3.2306497156014906,0.030894617027511038,-0.22824695247054547,-0.16304347134508207,-0.0012581004565036626,0.030894617027511038,0.09500082791205905,-1.209424370050621,0.09500082791205905,3.2306497156014906,0.15884550726049723,0.34885740302862467	3643
Lysosomal lumen	21	37	3.383473503718057	0.000715751135083	Q14108,P10253,O14773,P54802,Q9UM22,P06280,P16278,P15586,Q8NHP8,P10619,O00754,P07602,Q8IV08,P50897,Q9UMR5,P08236,P04066,O00584,P61916,P11117,O43681	Localization	GO Cellular component	msigdb_gocc	255,266,391,147,22,153,155,410,58,59,435,69,73,72,77,455,228,103,351,236,118	103,435,391,118,703,228,153,1013,69,3538,1789,455,266,59,236,2144,2332,410,155,2869,707,847,3578,2432,72,147,351,3473,255,73,1663,58,520,3002,1064,22,77	1.943054324684516,0.7224199472328477,0.7838890695289682,1.7982903969638317,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,-0.06576592628969985,0.6916031594494587,1.0578712931665288,2.5402599154147643,1.1482768495977804,-0.19560956934146895,-0.2609563355332265,0.7531817696547146,1.5350292358486646,-0.525313577596298,0.44303477605405855,0.34885740302862467,-1.63783022894056,-0.29373844618932715,2.399583395405736,1.5644560394229112,0.8756881681175116,-1.174345720866778,1.08805639508316,2.399583395405736,-0.0012581004565036626,2.5682865023912558,0.6298028841948623,-0.5921770650124923,0.25413257026133235,4.373525061543824,2.314734830304036	3643
Peptidase activity	37	124	3.3706012196274537	0.0007500434599805	P42785,Q4J6C6,Q9HD42,P20618,O14773,P28072,Q8TCT8,P60900,P55786,Q9HB40,Q9UIQ6,P28070,P28074,P02786,Q9BXS4,P42892,Q92542,P10619,P49721,P22695,O75976,O15484,P78536,Q9H300,Q9H3G5,Q96K76,P52888,Q9NQH7,P17655,Q9NZ08,Q93009,Q16740,Q9BT78,Q99538,Q99436,O75844,Q9UPT9	Functions	GO Molecular function	msigdb_gomf	4,135,276,137,391,146,158,283,31,35,42,164,41,409,50,53,317,59,60,311,206,209,216,491,359,485,98,386,473,245,481,113,385,520,121,248,124	745,1135,391,1212,209,2216,1137,2137,248,206,2052,2327,2966,885,409,2864,3151,2222,59,3108,3109,2760,473,137,311,2802,164,146,41,3323,2659,3030,1544,1973,1019,4,53,1977,3201,2878,60,3298,1229,1631,98,1980,1554,1632,1888,31,283,2245,2254,216,3614,2355,2883,658,3347,803,2773,2361,2986,113,1652,135,2891,1042,3085,3045,2776,1906,2004,1322,2005,601,2989,675,158,3492,317,1921,1417,2100,3133,2378,481,913,3395,3311,914,485,1188,730,1264,121,3176,3177,520,2737,3179,385,50,1422,491,359,3554,2630,1515,35,2303,276,386,3241,524,3137,245,42,124,2638,1132,1769,608,2697	0.4117022638315761,0.19067127264620573,0.7838890695289682,0.15884550726049723,1.268129085929357,-0.22824695247054547,0.19067127264620573,-0.19560956934146895,1.118191455601226,1.2979715997804608,-0.16304347134508207,-0.2609563355332265,-0.5921770650124923,0.31734400267200297,0.7531817696547146,-0.525313577596298,-0.726880811724572,-0.22824695247054547,2.5402599154147643,-0.6930805097254553,-0.6930805097254553,-0.4587663248239629,0.6607309570482511,1.623176179314646,0.9670119136618348,-0.4920008457387619,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.8971691305719629,-0.3925286203228279,-0.6257295573052645,0.030894617027511038,-0.13054795621506413,0.25413257026133235,6.233993929662534,2.763483088965262,-0.13054795621506413,-0.7607655898218467,-0.525313577596298,2.5402599154147643,-0.8629365633590367,0.15884550726049723,-0.0012581004565036626,1.9718833674139287,-0.13054795621506413,0.030894617027511038,-0.0012581004565036626,-0.098122333905974,3.6085359292973544,1.027635769907882,-0.22824695247054547,-0.22824695247054547,1.2382387072449188,-2.1915754284517606,-0.2609563355332265,-0.525313577596298,0.47430803058067816,-0.931491220478586,0.3803099800917596,-0.4587663248239629,-0.2609563355332265,-0.5921770650124923,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,-0.525313577596298,0.25413257026133235,-0.6593637349435877,-0.6257295573052645,-0.4587663248239629,-0.098122333905974,-0.13054795621506413,0.12695555655645674,-0.13054795621506413,0.5366787829519797,-0.5921770650124923,0.47430803058067816,1.5350292358486646,-1.209424370050621,0.9670119136618348,-0.098122333905974,0.09500082791205905,-0.16304347134508207,-0.6930805097254553,-0.2609563355332265,0.6607309570482511,0.31734400267200297,-1.0004082879139022,-0.8629365633590367,0.31734400267200297,0.6607309570482511,0.19067127264620573,0.44303477605405855,0.15884550726049723,1.7692119702003737,-0.726880811724572,-0.726880811724572,0.6298028841948623,-0.42560918711049844,-0.726880811724572,0.8145422833591529,2.901874777421383,0.09500082791205905,0.6607309570482511,0.8756881681175116,-1.4576838354723742,-0.3595238272390506,0.06298071889501843,3.447308651903207,-0.22824695247054547,1.0578712931665288,0.8145422833591529,-0.7947358122572576,0.6298028841948623,-0.6930805097254553,1.1482768495977804,3.2306497156014906,1.7692119702003737,-0.3595238272390506,0.2224334357534765,-0.03347806686168351,0.5366787829519797,-0.3925286203228279	3643
Action tremor	21	60	3.3194545108816413	0.0009019349798529	Q99720,Q14108,O75027,O14773,Q9NR77,O75787,Q9H6K4,Q9BUB7,P03886,P20700,P07602,Q15233,P00846,Q9Y4W6,Q9Y448,P41440,O75569,O75306,Q01082,O43681,Q9NQH7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,255,21,391,32,296,579,447,62,310,69,567,74,608,348,90,350,471,365,118,386	1862,391,1210,2571,118,21,471,350,296,791,1782,2705,74,62,2967,2758,2654,69,1874,2925,1222,2225,310,1293,3028,592,1971,754,90,2877,1885,2242,1088,1387,365,955,255,567,1042,2452,3491,1407,3393,859,1664,2622,1675,3177,2,2112,447,579,386,32,1064,1521,2562,3286,348,608	-0.098122333905974,0.7838890695289682,0.15884550726049723,-0.3595238272390506,1.7982903969638317,4.373525061543824,0.6607309570482511,0.8756881681175116,0.9973494401983068,0.3803099800917596,-0.06576592628969985,-0.42560918711049844,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.4587663248239629,-0.3925286203228279,2.427791890653298,-0.098122333905974,-0.5587053640309138,0.15884550726049723,-0.22824695247054547,0.9670119136618348,0.12695555655645674,-0.6257295573052645,0.5366787829519797,-0.13054795621506413,0.4117022638315761,2.058127752852981,-0.525313577596298,-0.098122333905974,-0.22824695247054547,0.2224334357534765,0.09500082791205905,0.845141841466991,0.2857692407025649,1.08805639508316,0.5677772700633923,0.25413257026133235,-0.29373844618932715,-1.209424370050621,0.09500082791205905,-1.0004082879139022,0.34885740302862467,-0.0012581004565036626,-0.3595238272390506,-0.0012581004565036626,-0.726880811724572,8.21990109917503,-0.16304347134508207,0.7224199472328477,0.5677772700633923,0.8145422833591529,3.6085359292973544,0.25413257026133235,0.06298071889501843,-0.3265940252928932,-0.8287924672030076,0.9061816816409076,0.5366787829519797	3643
Predicted secreted proteins	19	64	3.256048239647522	0.0011297455528587	P07942,Q08380,P14174,Q9UM22,Q9UMX5,P05067,Q9HB40,P22466,O75718,Q8WUJ1,Q8NDZ4,Q02818,P43490,Q9H9S5,P80303,O00584,Q9NZ08,Q15165,Q9BTY2	Functions	Protein Atlas Protein class	protein_atlas_protein_class	126,254,15,22,27,29,35,38,295,49,63,65,71,347,93,103,245,109,115	103,1606,1958,649,295,749,2138,1787,409,2508,29,2509,3191,126,1081,1704,3257,15,2760,1084,38,2516,616,3407,71,2584,2521,3515,351,2162,93,3614,657,65,1310,254,2082,1993,1031,109,2776,3592,1574,1744,676,3593,63,49,1182,468,677,2950,3560,115,3553,488,3554,2029,347,35,245,22,27,1603	1.943054324684516,-0.0012581004565036626,-0.13054795621506413,0.47430803058067816,0.9973494401983068,0.4117022638315761,-0.19560956934146895,-0.06576592628969985,0.7531817696547146,-0.3265940252928932,3.6353042018995785,-0.3265940252928932,-0.7607655898218467,1.7109272480905777,0.2224334357534765,-0.03347806686168351,-0.8287924672030076,4.964849362308119,-0.4587663248239629,0.2224334357534765,3.257840018273795,-0.3265940252928932,0.5055225334229401,-1.0350054838275398,2.399583395405736,-0.3595238272390506,-0.3265940252928932,-1.2798752825252815,0.8756881681175116,-0.19560956934146895,2.0006717808585845,-2.1915754284517606,0.47430803058067816,2.4840986629825825,0.12695555655645674,1.08805639508316,-0.16304347134508207,-0.13054795621506413,0.25413257026133235,1.914184390727662,-0.4587663248239629,-1.7470088834303552,0.030894617027511038,-0.03347806686168351,0.47430803058067816,-1.7470088834303552,2.512197372488192,2.9569963157150747,0.19067127264620573,0.6916031594494587,0.47430803058067816,-0.5587053640309138,-1.4935285643358234,1.8563207862044178,-1.4576838354723742,0.6607309570482511,-1.4576838354723742,-0.13054795621506413,0.9061816816409076,3.447308651903207,1.1482768495977804,4.373525061543824,3.795309279757627,0.030894617027511038	3643
Abnormality of peripheral nerves	11	51	3.2247614436621457	0.0012607767889791	Q9NR77,Q99720,P07602,O95831,P02545,Q71SY5,P39210,O43681,Q9GZY8,P07196,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,69,47,265,144,267,118,130,125,156	746,2212,118,1776,791,1456,47,265,125,69,1878,1222,1713,2711,267,2662,890,1467,1800,1155,2156,2238,2242,2349,3408,3471,156,3328,2087,2091,627,1825,2946,144,464,300,859,2734,813,2612,1675,1053,2,130,3533,32,1064,3243,1521,1767,693	0.4117022638315761,-0.22824695247054547,1.7982903969638317,-0.06576592628969985,0.3803099800917596,0.06298071889501843,3.0119856905575273,1.0578712931665288,1.7400910153055076,2.427791890653298,-0.098122333905974,0.15884550726049723,-0.03347806686168351,-0.42560918711049844,1.0578712931665288,-0.3925286203228279,0.31734400267200297,0.06298071889501843,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.22824695247054547,-0.22824695247054547,-0.2609563355332265,-1.0350054838275398,-1.174345720866778,1.5350292358486646,-0.8971691305719629,-0.16304347134508207,-0.16304347134508207,0.5055225334229401,-0.06576592628969985,-0.5587053640309138,1.5938382520831849,0.6916031594494587,0.9973494401983068,0.34885740302862467,-0.42560918711049844,0.3803099800917596,-0.3595238272390506,-0.0012581004565036626,0.25413257026133235,8.21990109917503,1.7109272480905777,-1.3507131280591325,3.6085359292973544,0.25413257026133235,-0.7947358122572576,0.06298071889501843,-0.03347806686168351,0.47430803058067816	3643
Organic acid transport	15	53	3.2169020606394807	0.0012958282596384	P11166,O95563,Q9UBX3,P23786,Q96H78,P80404,O43772,P53985,P14174,Q01650,Q7L0J3,O14678,P31751,P30825,P41440	Processes and pathways	GO Biological process	msigdb_gobp	279,152,306,200,274,413,13,44,15,143,17,176,364,54,90	176,2793,2049,1003,13,2754,2219,1450,3068,152,1286,2653,2508,3218,1874,1374,704,279,15,200,1622,54,592,364,1224,2342,90,3264,2073,44,440,413,143,2771,1317,765,662,3456,719,17,1177,2829,274,2906,2907,577,733,1057,306,924,1764,874,693	1.446478167816503,-0.4920008457387619,-0.16304347134508207,0.25413257026133235,5.243267115697605,-0.4587663248239629,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,0.12695555655645674,-0.3925286203228279,-0.3265940252928932,-0.7947358122572576,-0.098122333905974,0.09500082791205905,0.44303477605405855,1.027635769907882,4.964849362308119,1.327766595224347,-0.0012581004565036626,2.707887319665007,0.5366787829519797,0.845141841466991,0.15884550726049723,-0.2609563355332265,2.058127752852981,-0.8287924672030076,-0.16304347134508207,3.1215736355280526,0.7224199472328477,0.7531817696547146,1.5938382520831849,-0.4587663248239629,0.12695555655645674,0.4117022638315761,0.47430803058067816,-1.1393655482262741,0.44303477605405855,4.734981990697083,0.19067127264620573,-0.4920008457387619,1.0578712931665288,-0.525313577596298,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.9973494401983068,0.31734400267200297,-0.03347806686168351,0.34885740302862467,0.47430803058067816	3643
Molecular transducer activity	18	41	3.1844491617612665	0.0014502978310062	P11717,Q99720,Q14108,Q4VCS5,P20645,O15118,Q9P2E9,Q8WTV0,P22466,O15173,Q15629,O75787,Q9NWH9,Q5KU26,Q15375,Q99523,P10586,Q9NRA0	Functions	GO Molecular function	msigdb_gomf	154,2,255,512,37,252,407,8,38,199,509,296,371,396,418,114,119,227	1606,1072,252,199,3495,296,3218,1012,119,154,942,37,38,3615,1296,1976,2236,2669,1893,1395,1993,255,418,509,662,512,396,3305,8,2103,547,114,2,3056,227,371,407,991,1593,3432,877	-0.0012581004565036626,0.2224334357534765,1.08805639508316,1.327766595224347,-1.244601121096576,0.9973494401983068,-0.7947358122572576,0.25413257026133235,1.7982903969638317,1.5350292358486646,0.2857692407025649,3.284999162596966,3.257840018273795,-2.2291720974867153,0.12695555655645674,-0.13054795621506413,-0.22824695247054547,-0.3925286203228279,-0.098122333905974,0.09500082791205905,-0.13054795621506413,1.08805639508316,0.7531817696547146,0.6298028841948623,0.47430803058067816,0.6298028841948623,0.7838890695289682,-0.8629365633590367,5.940175937290734,-0.16304347134508207,0.5988184783374502,1.8563207862044178,8.21990109917503,-0.6257295573052645,1.2083001127798034,0.845141841466991,0.7838890695289682,0.2857692407025649,0.030894617027511038,-1.069696640684267,0.34885740302862467	3643
Vacuolar lumen	23	69	3.1826978389300504	0.0014590979600344	Q14108,P78371,P10253,O14773,P54802,Q9UM22,P06280,P16278,P15586,Q8NHP8,P10619,O00754,P07602,Q8IV08,P50897,Q9UMR5,P08236,P04066,O00584,P61916,Q9BTY2,P11117,O43681	Localization	GO Cellular component	msigdb_gocc	255,378,266,391,147,22,153,155,410,58,59,435,69,73,72,77,455,228,103,351,115,236,118	2322,103,435,391,118,2704,703,228,153,1013,3191,1701,69,3538,1789,455,266,59,236,2144,1964,2332,410,155,2869,3294,3197,3324,707,847,3578,2432,2935,72,2237,1805,1632,1806,147,2349,1023,351,2161,378,2813,2938,1238,3473,255,2087,73,1663,58,1417,1835,1507,2111,520,683,115,3002,3211,2693,2202,1064,22,77,2492,609	-0.2609563355332265,1.943054324684516,0.7224199472328477,0.7838890695289682,1.7982903969638317,-0.42560918711049844,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-0.7607655898218467,-0.03347806686168351,2.427791890653298,-1.3862754857551036,-0.06576592628969985,0.6916031594494587,1.0578712931665288,2.5402599154147643,1.1482768495977804,-0.19560956934146895,-0.13054795621506413,-0.2609563355332265,0.7531817696547146,1.5350292358486646,-0.525313577596298,-0.8629365633590367,-0.7607655898218467,-0.8971691305719629,0.44303477605405855,0.34885740302862467,-1.63783022894056,-0.29373844618932715,-0.5587053640309138,2.399583395405736,-0.22824695247054547,-0.06576592628969985,-0.0012581004565036626,-0.06576592628969985,1.5644560394229112,-0.2609563355332265,0.25413257026133235,0.8756881681175116,-0.19560956934146895,0.8145422833591529,-0.4920008457387619,-0.5587053640309138,0.15884550726049723,-1.174345720866778,1.08805639508316,-0.16304347134508207,2.399583395405736,-0.0012581004565036626,2.5682865023912558,0.09500082791205905,-0.06576592628969985,0.06298071889501843,-0.16304347134508207,0.6298028841948623,0.47430803058067816,1.8563207862044178,-0.5921770650124923,-0.7607655898218467,-0.3925286203228279,-0.19560956934146895,0.25413257026133235,4.373525061543824,2.314734830304036,-0.29373844618932715,0.5366787829519797	3643
Endopeptidase activity	24	70	3.168755492194062	0.001530931271773	Q4J6C6,P20618,O14773,P28072,Q8TCT8,P60900,P28070,P28074,Q9BXS4,P42892,Q92542,P49721,P22695,O15484,P78536,Q9H300,Q96K76,P52888,P17655,Q9NZ08,Q93009,Q16740,Q99436,O75844	Functions	GO Molecular function	msigdb_gomf	135,137,391,146,158,283,164,41,50,53,317,60,311,209,216,491,485,98,473,245,481,113,121,248	391,209,2216,1137,2137,248,2327,2864,3151,3109,2760,473,137,311,2802,164,146,41,2659,3030,1973,1019,53,1977,3201,2878,60,1631,98,1632,1888,283,2254,216,658,803,2773,2361,113,1652,135,1042,3085,3045,2776,601,2989,675,158,3492,317,1921,3133,2378,481,485,730,1264,121,520,2737,3179,50,1422,491,245,2638,1132,1769,608	0.7838890695289682,1.268129085929357,-0.22824695247054547,0.19067127264620573,-0.19560956934146895,1.118191455601226,-0.2609563355332265,-0.525313577596298,-0.726880811724572,-0.6930805097254553,-0.4587663248239629,0.6607309570482511,1.623176179314646,0.9670119136618348,-0.4920008457387619,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.3925286203228279,-0.6257295573052645,-0.13054795621506413,0.25413257026133235,2.763483088965262,-0.13054795621506413,-0.7607655898218467,-0.525313577596298,2.5402599154147643,-0.0012581004565036626,1.9718833674139287,-0.0012581004565036626,-0.098122333905974,1.027635769907882,-0.22824695247054547,1.2382387072449188,0.47430803058067816,0.3803099800917596,-0.4587663248239629,-0.2609563355332265,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,0.25413257026133235,-0.6593637349435877,-0.6257295573052645,-0.4587663248239629,0.5366787829519797,-0.5921770650124923,0.47430803058067816,1.5350292358486646,-1.209424370050621,0.9670119136618348,-0.098122333905974,-0.6930805097254553,-0.2609563355332265,0.6607309570482511,0.6607309570482511,0.44303477605405855,0.15884550726049723,1.7692119702003737,0.6298028841948623,-0.42560918711049844,-0.726880811724572,2.901874777421383,0.09500082791205905,0.6607309570482511,1.1482768495977804,-0.3595238272390506,0.2224334357534765,-0.03347806686168351,0.5366787829519797	3643
Protease	27	89	3.0778847922832253	0.0020847549511222	P42785,Q4J6C6,O14773,P28072,Q8TCT8,P55786,Q9HB40,Q9UIQ6,P28074,P42892,P10619,O75976,O15484,P78536,Q9H300,Q9H3G5,Q96K76,P52888,Q9NQH7,P17655,Q9NZ08,Q93009,Q16740,Q99538,Q99436,O75844,Q9UPT9	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	4,135,391,146,158,31,35,42,41,53,59,206,209,216,491,359,485,98,386,473,245,481,113,520,121,248,124	745,1135,391,209,1137,2137,248,206,2327,2966,885,3151,2222,59,3108,2760,473,146,41,3323,2659,1973,1019,4,53,1977,3201,3298,1631,98,1980,1554,1632,1888,31,2245,2254,216,3614,2355,2773,2361,2986,113,1652,135,1042,3085,2776,1322,2005,601,2989,675,158,3492,1921,3133,2378,481,3311,914,485,1188,730,1264,121,3177,520,2737,1422,491,359,3554,2630,1515,35,386,3241,524,3137,245,42,124,2638,1132,1769,608,2697	0.4117022638315761,0.19067127264620573,0.7838890695289682,1.268129085929357,0.19067127264620573,-0.19560956934146895,1.118191455601226,1.2979715997804608,-0.2609563355332265,-0.5921770650124923,0.31734400267200297,-0.726880811724572,-0.22824695247054547,2.5402599154147643,-0.6930805097254553,-0.4587663248239629,0.6607309570482511,1.5644560394229112,3.2306497156014906,-0.8971691305719629,-0.3925286203228279,-0.13054795621506413,0.25413257026133235,6.233993929662534,2.763483088965262,-0.13054795621506413,-0.7607655898218467,-0.8629365633590367,-0.0012581004565036626,1.9718833674139287,-0.13054795621506413,0.030894617027511038,-0.0012581004565036626,-0.098122333905974,3.6085359292973544,-0.22824695247054547,-0.22824695247054547,1.2382387072449188,-2.1915754284517606,-0.2609563355332265,-0.4587663248239629,-0.2609563355332265,-0.5921770650124923,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,0.25413257026133235,-0.6593637349435877,-0.4587663248239629,0.12695555655645674,-0.13054795621506413,0.5366787829519797,-0.5921770650124923,0.47430803058067816,1.5350292358486646,-1.209424370050621,-0.098122333905974,-0.6930805097254553,-0.2609563355332265,0.6607309570482511,-0.8629365633590367,0.31734400267200297,0.6607309570482511,0.19067127264620573,0.44303477605405855,0.15884550726049723,1.7692119702003737,-0.726880811724572,0.6298028841948623,-0.42560918711049844,0.09500082791205905,0.6607309570482511,0.8756881681175116,-1.4576838354723742,-0.3595238272390506,0.06298071889501843,3.447308651903207,0.8145422833591529,-0.7947358122572576,0.6298028841948623,-0.6930805097254553,1.1482768495977804,3.2306497156014906,1.7692119702003737,-0.3595238272390506,0.2224334357534765,-0.03347806686168351,0.5366787829519797,-0.3925286203228279	3643
Positive regulation of cytokine production	19	67	3.073877781514328	0.0021129597534974	P30511,P14174,Q01650,P14373,Q9NY93,P05067,Q9BY67,Q7Z434,O75787,O75116,Q13049,P23396,Q8WXW3,P78536,P41440,Q9NRA0,Q9NUQ9,Q01082,O75955	Processes and pathways	GO Biological process	msigdb_gobp	138,15,143,395,429,29,304,420,296,293,188,437,468,216,90,227,102,365,249	1209,1210,1001,2502,1216,2794,293,296,249,1698,2757,2508,2863,590,29,1789,1081,653,2511,3256,1704,15,395,1878,2225,437,616,2928,138,2229,2764,1296,90,756,795,1557,216,2881,365,143,800,1815,1394,188,1092,2672,2267,1097,420,468,2178,1749,1834,978,1923,1674,3177,3053,919,304,522,2394,227,989,102,429,2308	0.15884550726049723,0.15884550726049723,0.25413257026133235,-0.3265940252928932,0.15884550726049723,-0.4920008457387619,0.9973494401983068,0.9973494401983068,1.118191455601226,-0.03347806686168351,-0.4587663248239629,-0.3265940252928932,-0.525313577596298,0.5366787829519797,3.6353042018995785,-0.06576592628969985,0.2224334357534765,0.47430803058067816,-0.3265940252928932,-0.8287924672030076,-0.03347806686168351,4.964849362308119,0.7838890695289682,-0.098122333905974,-0.22824695247054547,0.7224199472328477,0.5055225334229401,-0.5587053640309138,1.623176179314646,-0.22824695247054547,-0.4587663248239629,0.12695555655645674,2.058127752852981,0.4117022638315761,0.3803099800917596,0.030894617027511038,1.2382387072449188,-0.525313577596298,0.845141841466991,1.5938382520831849,0.3803099800917596,-0.06576592628969985,0.09500082791205905,1.387215394486587,0.2224334357534765,-0.3925286203228279,-0.22824695247054547,0.2224334357534765,0.7531817696547146,0.6916031594494587,-0.19560956934146895,-0.03347806686168351,-0.06576592628969985,0.2857692407025649,-0.098122333905974,-0.0012581004565036626,-0.726880811724572,-0.6257295573052645,0.31734400267200297,0.9973494401983068,0.6298028841948623,-0.2609563355332265,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.7531817696547146,-0.22824695247054547	3643
Cell surface	30	95	3.070144053998903	0.0021395554749807	Q4VCS5,P26038,Q8WTV0,Q9BQT9,P30511,P14174,Q01650,O75298,Q9H813,P00390,P05067,P11717,P10321,P02786,O75787,P42892,P00813,O75592,P51790,Q13641,P30533,O15484,P78536,P41440,P17655,Q9NWH9,Q99523,P25705,P15291,O75955	Localization	GO Cellular component	msigdb_gocc	512,501,8,275,138,15,143,393,150,25,29,154,532,409,296,53,56,186,459,329,457,209,216,90,473,371,114,237,112,249	1072,1073,1003,209,1137,393,531,186,296,249,3365,25,56,3617,1872,409,2508,590,29,3218,2141,3190,1012,3150,3191,1374,704,1457,2866,1081,532,3256,1704,887,1082,154,2656,15,2760,112,942,473,1084,843,237,501,2658,2066,3030,138,457,2229,90,53,2236,459,1888,2159,216,1308,143,1893,1310,1395,1727,2082,1894,1398,2596,2528,329,2445,1031,1033,3042,512,1909,1177,3492,8,2377,1049,3447,114,3235,275,2293,150,3480,371,3246,3432,2206,1443,3315	0.2224334357534765,0.2224334357534765,0.25413257026133235,1.268129085929357,0.19067127264620573,0.7838890695289682,0.5988184783374502,1.387215394486587,0.9973494401983068,1.118191455601226,-0.9659039071751861,3.9014137223503935,2.6800374279695216,-2.342454069604444,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,3.6353042018995785,-0.7947358122572576,-0.19560956934146895,-0.7607655898218467,0.25413257026133235,-0.726880811724572,-0.7607655898218467,0.09500082791205905,0.44303477605405855,0.06298071889501843,-0.525313577596298,0.2224334357534765,0.5988184783374502,-0.8287924672030076,-0.03347806686168351,0.31734400267200297,0.2224334357534765,1.5350292358486646,-0.3925286203228279,4.964849362308119,-0.4587663248239629,1.8563207862044178,0.2857692407025649,0.6607309570482511,0.2224334357534765,0.34885740302862467,1.1482768495977804,0.6298028841948623,-0.3925286203228279,-0.16304347134508207,-0.6257295573052645,1.623176179314646,0.6916031594494587,-0.22824695247054547,2.058127752852981,2.763483088965262,-0.22824695247054547,0.6916031594494587,-0.098122333905974,-0.19560956934146895,1.2382387072449188,0.12695555655645674,1.5938382520831849,-0.098122333905974,0.12695555655645674,0.09500082791205905,-0.03347806686168351,-0.16304347134508207,-0.098122333905974,0.09500082791205905,-0.3595238272390506,-0.3265940252928932,0.9366227945511973,-0.29373844618932715,0.25413257026133235,0.25413257026133235,-0.6257295573052645,0.6298028841948623,-0.098122333905974,0.19067127264620573,-1.209424370050621,5.940175937290734,-0.2609563355332265,0.25413257026133235,-1.104482929673742,1.8563207862044178,-0.7947358122572576,1.0578712931665288,-0.22824695247054547,1.5644560394229112,-1.174345720866778,0.845141841466991,-0.7947358122572576,-1.069696640684267,-0.19560956934146895,0.09500082791205905,-0.8629365633590367	3643
transporter	15	66	3.0657334659068307	0.0021713678276242	Q9NR77,Q15012,P55735,P53985,O43772,Q9HD45,Q01650,Q9C0E2,Q567V2,P39210,O43681,Q8N1F7,P41440,Q9NUN5,Q99805	Functions	Panther Protein class	panther_protein_class	32,353,201,44,13,277,143,175,18,267,118,342,90,123,426	556,2917,2792,3511,2135,836,1283,118,13,648,1216,2795,2701,884,1972,2431,267,90,2934,2345,850,1386,1980,2073,44,1555,1982,201,798,2807,2163,143,2440,2268,353,417,18,1657,722,342,1498,861,3307,975,1331,2102,679,1837,2021,682,426,2292,3333,175,733,1350,1352,277,32,123,1763,3339,2308,2316,1604,693	0.5677772700633923,-0.5587053640309138,-0.4920008457387619,-1.2798752825252815,-0.19560956934146895,0.34885740302862467,0.12695555655645674,1.7982903969638317,5.243267115697605,0.47430803058067816,0.15884550726049723,-0.4920008457387619,-0.42560918711049844,0.31734400267200297,-0.13054795621506413,-0.29373844618932715,1.0578712931665288,2.058127752852981,-0.5587053640309138,-0.2609563355332265,0.34885740302862467,0.09500082791205905,-0.13054795621506413,-0.16304347134508207,3.1215736355280526,0.030894617027511038,-0.13054795621506413,1.327766595224347,0.3803099800917596,-0.4920008457387619,-0.19560956934146895,1.5938382520831849,-0.29373844618932715,-0.22824695247054547,0.8756881681175116,0.7531817696547146,4.529028557834912,-0.0012581004565036626,0.44303477605405855,0.9061816816409076,0.06298071889501843,0.34885740302862467,-0.8629365633590367,0.2857692407025649,0.12695555655645674,-0.16304347134508207,0.47430803058067816,-0.06576592628969985,-0.13054795621506413,0.47430803058067816,0.7531817696547146,-0.22824695247054547,-0.8971691305719629,1.4760406150941263,0.44303477605405855,0.12695555655645674,0.12695555655645674,1.0578712931665288,3.6085359292973544,1.7692119702003737,-0.03347806686168351,-0.8971691305719629,-0.22824695247054547,-0.22824695247054547,0.030894617027511038,0.47430803058067816	3643
Receptor	12	33	3.0653468013613643	0.0021741773038059	Q9NR77,P11717,Q14108,P20645,Q8WTV0,O75787,A6NIH7,Q13641,Q567V2,P57105,P39210,Q9UQB8	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	32,154,255,37,8,296,46,329,18,238,267,26	46,2135,1695,2860,3483,296,2798,2328,3218,154,37,267,1976,238,540,329,255,3041,18,3045,3305,2822,8,1669,3056,1352,636,32,3377,360,3400,26,1443	3.0942250631129866,-0.19560956934146895,-0.03347806686168351,-0.525313577596298,-1.209424370050621,0.9973494401983068,-0.4920008457387619,-0.2609563355332265,-0.7947358122572576,1.5350292358486646,3.284999162596966,1.0578712931665288,-0.13054795621506413,1.1482768495977804,0.5988184783374502,0.9366227945511973,1.08805639508316,-0.6257295573052645,4.529028557834912,-0.6257295573052645,-0.8629365633590367,-0.4920008457387619,5.940175937290734,-0.0012581004565036626,-0.6257295573052645,0.12695555655645674,0.5055225334229401,3.6085359292973544,-0.9659039071751861,0.8756881681175116,-1.0004082879139022,3.9014137223503935,0.09500082791205905	3643
Abnormal peripheral nervous system physiology	12	55	3.036004101587628	0.002397361031472	Q9NR77,Q99720,P07602,Q7Z406,O95831,P02545,Q71SY5,P39210,O43681,Q9GZY8,P07196,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,69,300,47,265,144,267,118,130,125,156	746,2212,118,1776,529,791,1456,47,265,125,69,1878,1222,310,1713,2711,267,2662,890,1467,1800,1155,2156,2238,2242,2349,3408,3471,156,3328,3490,2087,2091,627,1825,2946,144,464,300,859,2734,813,1675,1053,2,130,3533,2482,32,988,1064,3243,1521,1767,693	0.4117022638315761,-0.22824695247054547,1.7982903969638317,-0.06576592628969985,0.5988184783374502,0.3803099800917596,0.06298071889501843,3.0119856905575273,1.0578712931665288,1.7400910153055076,2.427791890653298,-0.098122333905974,0.15884550726049723,0.9670119136618348,-0.03347806686168351,-0.42560918711049844,1.0578712931665288,-0.3925286203228279,0.31734400267200297,0.06298071889501843,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.22824695247054547,-0.22824695247054547,-0.2609563355332265,-1.0350054838275398,-1.174345720866778,1.5350292358486646,-0.8971691305719629,-1.209424370050621,-0.16304347134508207,-0.16304347134508207,0.5055225334229401,-0.06576592628969985,-0.5587053640309138,1.5938382520831849,0.6916031594494587,0.9973494401983068,0.34885740302862467,-0.42560918711049844,0.3803099800917596,-0.0012581004565036626,0.25413257026133235,8.21990109917503,1.7109272480905777,-1.3507131280591325,-0.29373844618932715,3.6085359292973544,0.2857692407025649,0.25413257026133235,-0.7947358122572576,0.06298071889501843,-0.03347806686168351,0.47430803058067816	3643
Juvenile onset	16	46	3.024299153646645	0.002492098809349	P35579,Q9NR77,P16278,O15118,P22466,Q03252,P02545,P06753,Q14566,Q8NHS3,P39210,O75027,P54802,P07196,P41440,P06280	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	280,32,155,252,38,207,265,394,380,52,267,21,147,125,90,153	391,252,21,2652,265,2758,153,394,125,155,38,2064,707,280,3296,3578,267,1296,90,1467,618,2715,849,1155,2666,460,147,798,207,2358,1645,3473,1818,380,2533,3412,3393,52,1668,2612,2115,1936,2743,32,3245,1604	0.7838890695289682,1.08805639508316,4.373525061543824,-0.3925286203228279,1.0578712931665288,-0.4587663248239629,1.5350292358486646,0.7838890695289682,1.7400910153055076,1.5350292358486646,3.257840018273795,-0.16304347134508207,0.44303477605405855,1.027635769907882,-0.8629365633590367,-1.63783022894056,1.0578712931665288,0.12695555655645674,2.058127752852981,0.06298071889501843,0.5055225334229401,-0.42560918711049844,0.34885740302862467,0.19067127264620573,-0.3925286203228279,0.6916031594494587,1.5644560394229112,0.3803099800917596,1.2979715997804608,-0.2609563355332265,-0.0012581004565036626,-1.174345720866778,-0.06576592628969985,0.8145422833591529,-0.3265940252928932,-1.0350054838275398,-1.0004082879139022,2.818941470146897,-0.0012581004565036626,-0.3595238272390506,-0.16304347134508207,-0.098122333905974,-0.42560918711049844,3.6085359292973544,-0.7947358122572576,0.030894617027511038	3643
Abnormal nerve conduction velocity	10	44	3.0229277223806146	0.0025034202730587	Q9NR77,Q99720,P07602,O95831,P02545,Q71SY5,O43681,Q9GZY8,P07196,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,69,47,265,144,118,130,125,156	746,118,1776,791,47,265,125,69,1878,1222,1713,2711,2662,890,1467,1800,1155,2156,2238,2242,2349,3408,3471,156,3328,2087,2091,627,2946,144,464,300,859,2734,1053,2,130,3533,32,1064,3243,1521,1767,693	0.4117022638315761,1.7982903969638317,-0.06576592628969985,0.3803099800917596,3.0119856905575273,1.0578712931665288,1.7400910153055076,2.427791890653298,-0.098122333905974,0.15884550726049723,-0.03347806686168351,-0.42560918711049844,-0.3925286203228279,0.31734400267200297,0.06298071889501843,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.22824695247054547,-0.22824695247054547,-0.2609563355332265,-1.0350054838275398,-1.174345720866778,1.5350292358486646,-0.8971691305719629,-0.16304347134508207,-0.16304347134508207,0.5055225334229401,-0.5587053640309138,1.5938382520831849,0.6916031594494587,0.9973494401983068,0.34885740302862467,-0.42560918711049844,0.25413257026133235,8.21990109917503,1.7109272480905777,-1.3507131280591325,3.6085359292973544,0.25413257026133235,-0.7947358122572576,0.06298071889501843,-0.03347806686168351,0.47430803058067816	3643
Abnormal metatarsal morphology	12	31	3.000973677171612	0.0026911782779082	Q8WVQ1,Q96L58,Q7RTS9,Q15392,O43505,Q03252,Q9Y448,Q9H9S5,P08236,Q9Y366,Q9UBM7,O96028	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	423,303,11,45,205,207,348,347,455,290,289,87	2502,205,2412,3288,1372,87,455,1377,2145,2337,3197,592,1802,207,1396,1562,900,45,1038,11,480,423,303,2020,2390,347,1429,289,2041,290,348	-0.3265940252928932,1.2979715997804608,-0.29373844618932715,-0.8629365633590367,0.09500082791205905,2.11542427763213,0.6916031594494587,0.09500082791205905,-0.19560956934146895,-0.2609563355332265,-0.7607655898218467,0.5366787829519797,-0.06576592628969985,1.2979715997804608,0.09500082791205905,0.030894617027511038,0.31734400267200297,3.1215736355280526,0.25413257026133235,5.543953911878619,0.6607309570482511,0.7531817696547146,0.9973494401983068,-0.13054795621506413,-0.2609563355332265,0.9061816816409076,0.09500082791205905,1.027635769907882,-0.13054795621506413,1.027635769907882,0.9061816816409076	3643
Signal transduction by p53 class mediator	8	50	2.989005817904187	0.002798868022501	P46379,Q8N2F6,Q9UNS2,Q01664,Q7LG56,P14174,Q13573,O75844	Processes and pathways	GO Biological process	msigdb_gobp	3,467,106,327,464,15,88,248	2323,999,2211,1366,933,1864,1217,1615,248,1616,2651,1288,15,1459,592,1086,1883,2933,3,1466,1808,1724,896,1809,1985,2249,2078,1558,2252,327,88,1817,2361,2600,464,467,481,1923,1925,1187,1928,730,2548,3334,2473,2030,1685,784,1595,106	-0.2609563355332265,0.25413257026133235,-0.22824695247054547,0.09500082791205905,0.2857692407025649,-0.098122333905974,0.15884550726049723,-0.0012581004565036626,1.118191455601226,-0.0012581004565036626,-0.3925286203228279,0.12695555655645674,4.964849362308119,0.06298071889501843,0.5366787829519797,0.2224334357534765,-0.098122333905974,-0.5587053640309138,7.00443820279511,0.06298071889501843,-0.06576592628969985,-0.03347806686168351,0.31734400267200297,-0.06576592628969985,-0.13054795621506413,-0.22824695247054547,-0.16304347134508207,0.030894617027511038,-0.22824695247054547,0.9366227945511973,2.11542427763213,-0.06576592628969985,-0.2609563355332265,-0.3595238272390506,0.6916031594494587,0.6916031594494587,0.6607309570482511,-0.098122333905974,-0.098122333905974,0.19067127264620573,-0.098122333905974,0.44303477605405855,-0.3265940252928932,-0.8971691305719629,-0.29373844618932715,-0.13054795621506413,-0.0012581004565036626,0.4117022638315761,0.030894617027511038,1.943054324684516	3643
Organic anion transport	22	56	2.947081804897515	0.0032078832748594	Q86VD7,Q14728,Q01650,P14174,Q7L0J3,Q9HC21,Q9Y619,P11166,O00400,O95563,Q9UBX3,P80404,Q9BQT8,Q8TB61,P53985,Q15758,P30825,P55011,Q9H2D1,P07602,P41440,Q9Y6M7	Processes and pathways	GO Biological process	msigdb_gobp	256,624,143,15,17,553,693,279,646,152,306,413,577,573,44,662,54,440,733,69,90,361	646,2793,2049,1003,2754,2219,1450,3068,152,2508,1962,1873,3218,69,704,3219,279,2331,1145,15,1622,54,2342,90,2073,44,440,413,143,2771,1395,624,1317,765,662,2274,2366,3456,17,256,1177,573,2829,2906,2907,2292,577,733,1057,553,1432,1064,306,924,693,361	0.47430803058067816,-0.4920008457387619,-0.16304347134508207,0.25413257026133235,-0.4587663248239629,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.3265940252928932,-0.13054795621506413,-0.098122333905974,-0.7947358122572576,2.427791890653298,0.44303477605405855,-0.7947358122572576,1.027635769907882,-0.2609563355332265,0.19067127264620573,4.964849362308119,-0.0012581004565036626,2.707887319665007,-0.2609563355332265,2.058127752852981,-0.16304347134508207,3.1215736355280526,0.7224199472328477,0.7531817696547146,1.5938382520831849,-0.4587663248239629,0.09500082791205905,0.5055225334229401,0.12695555655645674,0.4117022638315761,0.47430803058067816,-0.22824695247054547,-0.2609563355332265,-1.1393655482262741,4.734981990697083,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,-0.525313577596298,-0.22824695247054547,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.5988184783374502,0.09500082791205905,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.8756881681175116	3643
Lytic vacuole organization	13	32	2.94300553477562	0.0032504260700367	Q14108,P50897,Q9HC07,O75787,Q96ED9,P10253,O14773,P54802,Q8NHS3,O75503,P11117,Q9NWW5,Q14457	Processes and pathways	GO Biological process	msigdb_gobp	255,72,405,296,179,266,391,147,52,24,236,251,189	1952,391,24,296,703,3538,266,236,1086,72,2156,147,2075,801,255,189,1036,2001,771,1914,52,2180,179,2624,448,405,3337,251,2633,643,1690,1437	-0.13054795621506413,0.7838890695289682,4.11230346222967,0.9973494401983068,0.44303477605405855,-1.3862754857551036,1.0578712931665288,1.1482768495977804,0.2224334357534765,2.399583395405736,-0.19560956934146895,1.5644560394229112,-0.16304347134508207,0.3803099800917596,1.08805639508316,1.387215394486587,0.25413257026133235,-0.13054795621506413,0.4117022638315761,-0.098122333905974,2.818941470146897,-0.19560956934146895,1.446478167816503,-0.3595238272390506,0.7224199472328477,0.7838890695289682,-0.8971691305719629,1.118191455601226,-0.3595238272390506,0.5055225334229401,-0.0012581004565036626,0.09500082791205905	3643
Vacuole	68	249	2.942145542536579	0.0032594669530479	Q14108,P42785,P78371,O15118,Q8WTV0,Q9HD42,Q9HC07,P30511,Q01650,P10253,O14773,Q9UM22,P54802,O75503,Q8TCT8,Q8NCC3,P06280,P16278,Q9UHG3,P19474,P20645,Q9UIQ6,Q9Y487,Q07065,O75787,P15586,O14678,Q9BXS4,Q8NHS3,P42892,P00813,Q8NHP8,Q92542,P10619,Q14457,P33176,O00754,P07602,Q8IV08,P50897,P55735,Q8IY95,Q96RU3,Q9UMR5,P51790,Q93050,P08236,P51798,P41440,Q9NRA0,P04066,Q15012,O00584,P61916,P51809,P17655,O15260,Q15165,Q86YV9,Q99523,Q9BTY2,P15291,P11117,Q969Q5,O43681,O75955,Q9NQX7,Q9NUN5	Localization	GO Cellular component	msigdb_gocc	255,4,378,252,8,276,405,138,143,266,391,22,147,24,158,28,153,155,430,36,37,42,43,173,296,410,176,50,52,53,56,58,317,59,189,312,435,69,73,72,201,466,204,77,459,82,455,460,90,227,228,353,103,351,476,473,108,109,479,114,115,112,236,482,118,249,122,123	1952,2322,103,435,2792,176,391,1774,252,108,586,3187,2963,118,2860,1138,588,2700,1078,3361,24,296,249,2798,1456,2507,2328,2704,56,3617,703,228,3104,153,1013,3191,3151,1701,69,3538,1789,3106,704,455,1457,2057,1702,2143,266,59,3219,236,2144,1964,1082,2332,112,410,155,473,2869,36,37,3294,2061,3422,2927,563,3073,2658,3197,2580,3324,138,3407,2873,312,707,1624,847,3578,2661,3200,90,1086,4,53,1977,1628,2432,2935,1020,72,2237,3265,1300,2156,1552,459,3607,460,476,1805,1632,2348,1806,147,2349,201,2768,2717,1723,2586,2075,1023,2587,351,3571,2251,1636,2161,378,952,1560,2813,143,2257,622,2938,173,2772,1160,1727,1398,898,1238,3473,1030,255,2087,189,3301,1036,353,963,109,854,2532,541,1320,3390,666,2001,3126,1911,479,73,1177,466,1914,1663,28,1180,1916,58,52,3478,158,8,3356,2099,317,1417,82,482,2380,2180,1835,1050,679,574,2624,1675,204,1507,114,2111,520,3234,864,3179,683,1929,115,3642,3002,50,1933,3237,1423,3211,2115,3479,1349,1936,1350,2391,2693,2303,405,1844,276,1193,122,227,1195,123,2912,3337,2307,1850,2202,1064,739,1199,2633,1065,1944,430,2401,42,2041,22,1595,77,2043,2309,2127,2492,1690,1599,1436,3493,1437,43,1280,609,995,877	-0.13054795621506413,-0.2609563355332265,1.943054324684516,0.7224199472328477,-0.4920008457387619,1.446478167816503,0.7838890695289682,-0.06576592628969985,1.08805639508316,1.914184390727662,0.5366787829519797,-0.7607655898218467,-0.5921770650124923,1.7982903969638317,-0.525313577596298,0.19067127264620573,0.5366787829519797,-0.42560918711049844,0.2224334357534765,-0.9659039071751861,4.11230346222967,0.9973494401983068,1.118191455601226,-0.4920008457387619,0.06298071889501843,-0.3265940252928932,-0.2609563355332265,-0.42560918711049844,2.6800374279695216,-2.342454069604444,0.44303477605405855,1.1783129469800828,-0.6930805097254553,1.5350292358486646,0.25413257026133235,-0.7607655898218467,-0.726880811724572,-0.03347806686168351,2.427791890653298,-1.3862754857551036,-0.06576592628969985,-0.6930805097254553,0.44303477605405855,0.6916031594494587,0.06298071889501843,-0.16304347134508207,-0.03347806686168351,-0.19560956934146895,1.0578712931665288,2.5402599154147643,-0.7947358122572576,1.1482768495977804,-0.19560956934146895,-0.13054795621506413,0.2224334357534765,-0.2609563355332265,1.8563207862044178,0.7531817696547146,1.5350292358486646,0.6607309570482511,-0.525313577596298,3.3662912544280115,3.284999162596966,-0.8629365633590367,-0.16304347134508207,-1.069696640684267,-0.5587053640309138,0.5677772700633923,-0.6593637349435877,-0.3925286203228279,-0.7607655898218467,-0.3595238272390506,-0.8971691305719629,1.623176179314646,-1.0350054838275398,-0.525313577596298,0.9670119136618348,0.44303477605405855,-0.0012581004565036626,0.34885740302862467,-1.63783022894056,-0.3925286203228279,-0.7607655898218467,2.058127752852981,0.2224334357534765,6.233993929662534,2.763483088965262,-0.13054795621506413,-0.0012581004565036626,-0.29373844618932715,-0.5587053640309138,0.25413257026133235,2.399583395405736,-0.22824695247054547,-0.8287924672030076,0.12695555655645674,-0.19560956934146895,0.030894617027511038,0.6916031594494587,-2.042021033479733,0.6916031594494587,0.6607309570482511,-0.06576592628969985,-0.0012581004565036626,-0.2609563355332265,-0.06576592628969985,1.5644560394229112,-0.2609563355332265,1.327766595224347,-0.4587663248239629,-0.42560918711049844,-0.03347806686168351,-0.3595238272390506,-0.16304347134508207,0.25413257026133235,-0.3595238272390506,0.8756881681175116,-1.5654960467228805,-0.22824695247054547,-0.0012581004565036626,-0.19560956934146895,0.8145422833591529,0.2857692407025649,0.030894617027511038,-0.4920008457387619,1.5938382520831849,-0.22824695247054547,0.5055225334229401,-0.5587053640309138,1.4760406150941263,-0.4587663248239629,0.19067127264620573,-0.03347806686168351,0.09500082791205905,0.31734400267200297,0.15884550726049723,-1.174345720866778,0.25413257026133235,1.08805639508316,-0.16304347134508207,1.387215394486587,-0.8629365633590367,0.25413257026133235,0.8756881681175116,0.2857692407025649,1.914184390727662,0.34885740302862467,-0.3265940252928932,0.5988184783374502,0.12695555655645674,-1.0004082879139022,0.47430803058067816,-0.13054795621506413,-0.6930805097254553,-0.098122333905974,0.6607309570482511,2.399583395405736,0.19067127264620573,0.6916031594494587,-0.098122333905974,-0.0012581004565036626,3.768713037747525,0.19067127264620573,-0.098122333905974,2.5682865023912558,2.818941470146897,-1.174345720866778,1.5350292358486646,5.940175937290734,-0.931491220478586,-0.16304347134508207,0.9670119136618348,0.09500082791205905,2.2010744460285183,0.6607309570482511,-0.2609563355332265,-0.19560956934146895,-0.06576592628969985,0.25413257026133235,0.47430803058067816,0.5677772700633923,-0.3595238272390506,-0.001258100456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Positive regulation of immune system process	34	129	2.917267887286333	0.0035311235523745	P23246,P46379,Q9HCL2,P30511,P14174,Q01650,Q9NY93,P05067,Q06481,Q9BY67,P02786,Q7Z434,P30825,P00813,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,P78536,Q9NPF0,Q9BX67,Q9NRA0,P31749,Q9NUQ9,P51809,Q9NQT5,O95219,Q99538,Q9H2U1,P26583,P49770	Processes and pathways	GO Biological process	msigdb_gobp	375,3,5,138,15,143,429,29,39,304,409,420,54,56,437,566,567,83,590,87,586,216,492,488,227,592,102,476,638,235,520,522,616,618	1770,1952,1605,2792,2050,586,2215,2502,2860,2794,2796,1698,1616,235,2053,87,2757,56,1872,409,2508,590,29,2509,1789,1081,653,3256,1704,1082,83,1146,15,941,3629,942,1084,2427,1878,375,437,616,3322,2658,3197,138,54,592,2229,3297,1547,890,1548,3117,3,3440,618,3344,476,1632,3160,3118,1156,1390,216,143,1893,2938,1815,39,1310,623,1394,1395,1727,2526,1645,1479,2672,1818,1315,566,567,1037,2532,1404,3042,1246,1100,2535,969,420,2949,973,1111,2178,2015,2377,1923,2619,914,1339,2621,1261,1928,1506,3177,520,3235,919,488,304,522,3533,5,492,638,2394,2743,227,989,102,429,828,3245,3098,2308,2040,2788	-0.06576592628969985,-0.13054795621506413,-0.0012581004565036626,-0.4920008457387619,-0.16304347134508207,0.5366787829519797,-0.22824695247054547,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,-0.4920008457387619,-0.03347806686168351,-0.0012581004565036626,1.1482768495977804,-0.16304347134508207,2.11542427763213,-0.4587663248239629,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,3.6353042018995785,-0.3265940252928932,-0.06576592628969985,0.2224334357534765,0.47430803058067816,-0.8287924672030076,-0.03347806686168351,0.2224334357534765,2.172563346869744,0.19067127264620573,4.964849362308119,0.2857692407025649,-2.997816021189173,0.2857692407025649,0.2224334357534765,-0.29373844618932715,-0.098122333905974,0.8145422833591529,0.7224199472328477,0.5055225334229401,-0.8971691305719629,-0.3925286203228279,-0.7607655898218467,1.623176179314646,2.707887319665007,0.5366787829519797,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,0.31734400267200297,0.030894617027511038,-0.6930805097254553,7.00443820279511,-1.104482929673742,0.5055225334229401,-0.931491220478586,0.6607309570482511,-0.0012581004565036626,-0.726880811724572,-0.6930805097254553,0.19067127264620573,0.09500082791205905,1.2382387072449188,1.5938382520831849,-0.098122333905974,-0.5587053640309138,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.5055225334229401,0.09500082791205905,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.0012581004565036626,0.06298071889501843,-0.3925286203228279,-0.06576592628969985,0.12695555655645674,0.5677772700633923,0.5677772700633923,0.25413257026133235,-0.3265940252928932,0.09500082791205905,-0.6257295573052645,0.15884550726049723,0.2224334357534765,-0.3265940252928932,0.2857692407025649,0.7531817696547146,-0.5587053640309138,0.2857692407025649,0.2224334357534765,-0.19560956934146895,-0.13054795621506413,-0.2609563355332265,-0.098122333905974,-0.3595238272390506,0.31734400267200297,0.12695555655645674,-0.3595238272390506,0.15884550726049723,-0.098122333905974,0.06298071889501843,-0.726880811724572,0.6298028841948623,-0.7947358122572576,0.31734400267200297,0.6607309570482511,0.9973494401983068,0.6298028841948623,-1.3507131280591325,6.233993929662534,0.6607309570482511,0.5055225334229401,-0.2609563355332265,-0.42560918711049844,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.7531817696547146,0.3803099800917596,-0.7947358122572576,-0.6593637349435877,-0.22824695247054547,-0.13054795621506413,-0.4587663248239629	3643
Endocytic vesicle	29	100	2.909599355901146	0.003618923390956	Q14108,Q4VCS5,Q8WTV0,P30511,O43493,Q5KU26,Q16625,P11717,P10321,P20645,Q06481,Q9Y487,P02786,Q9BZG1,Q14457,P33176,O00461,P51790,Q9Y4G8,Q93050,O43752,P61020,P04439,Q9H223,P51809,P08670,Q13555,Q969Q5,Q9NUN5	Localization	GO Cellular component	msigdb_gocc	255,512,8,138,142,396,541,154,532,37,39,43,409,448,189,312,70,459,81,82,454,596,590,490,476,104,105,482,123	2132,1207,70,1444,1774,586,1695,142,454,1213,2412,1449,2798,2328,3617,1872,409,590,1012,1789,104,1702,1703,532,887,1082,154,3591,2332,2513,2578,37,2658,3030,138,3520,312,1086,1155,3265,1300,2156,1552,2347,459,476,2348,1723,2805,596,1890,2075,2587,3077,2251,952,2257,1028,39,1727,2596,105,3348,255,1315,189,1036,2089,2269,902,1166,3124,2271,541,512,396,767,1655,970,1910,810,8,2015,82,482,1050,3234,448,3479,490,1937,123,3098,2041,1595,2127,43,81,1768,1204	-0.19560956934146895,0.15884550726049723,2.399583395405736,0.06298071889501843,-0.06576592628969985,0.5366787829519797,-0.03347806686168351,1.5938382520831849,0.6916031594494587,0.15884550726049723,-0.29373844618932715,0.06298071889501843,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,-0.098122333905974,0.7531817696547146,0.5366787829519797,0.25413257026133235,-0.06576592628969985,1.943054324684516,-0.03347806686168351,-0.03347806686168351,0.5988184783374502,0.31734400267200297,0.2224334357534765,1.5350292358486646,-1.7470088834303552,-0.2609563355332265,-0.3265940252928932,-0.3595238272390506,3.284999162596966,-0.3925286203228279,-0.6257295573052645,1.623176179314646,-1.315246174406957,0.9670119136618348,0.2224334357534765,0.19067127264620573,-0.8287924672030076,0.12695555655645674,-0.19560956934146895,0.030894617027511038,-0.2609563355332265,0.6916031594494587,0.6607309570482511,-0.2609563355332265,-0.03347806686168351,-0.4920008457387619,0.5366787829519797,-0.098122333905974,-0.16304347134508207,-0.3595238272390506,-0.6593637349435877,-0.22824695247054547,0.2857692407025649,-0.22824695247054547,0.25413257026133235,3.257840018273795,-0.03347806686168351,-0.3595238272390506,1.943054324684516,-0.931491220478586,1.08805639508316,0.12695555655645674,1.387215394486587,0.25413257026133235,-0.16304347134508207,-0.22824695247054547,0.31734400267200297,0.19067127264620573,-0.6930805097254553,-0.22824695247054547,0.5988184783374502,0.6298028841948623,0.7838890695289682,0.4117022638315761,-0.0012581004565036626,0.2857692407025649,-0.098122333905974,0.3803099800917596,5.940175937290734,-0.13054795621506413,2.2010744460285183,0.6607309570482511,0.25413257026133235,-0.7947358122572576,0.7224199472328477,-1.174345720866778,0.6607309570482511,-0.098122333905974,1.7692119702003737,-0.6593637349435877,-0.13054795621506413,0.030894617027511038,-0.16304347134508207,3.2306497156014906,2.2579809707838456,-0.03347806686168351,0.19067127264620573	3643
Toe walking	8	23	2.893916096587788	0.0038046981332888	Q99720,P07602,Q8TD16,O95831,P02545,Q01082,Q9H9S5,O43681	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,69,272,47,265,365,347,118	118,47,265,394,69,754,2232,849,2073,1387,2349,2880,365,1895,959,2946,3089,272,976,2,1581,347,1064	1.7982903969638317,3.0119856905575273,1.0578712931665288,0.7838890695289682,2.427791890653298,0.4117022638315761,-0.22824695247054547,0.34885740302862467,-0.16304347134508207,0.09500082791205905,-0.2609563355332265,-0.525313577596298,0.845141841466991,-0.098122333905974,0.2857692407025649,-0.5587053640309138,-0.6593637349435877,1.0578712931665288,0.2857692407025649,8.21990109917503,0.030894617027511038,0.9061816816409076,0.25413257026133235	3643
Receptor	14	43	2.891009415115238	0.0038400661583655	P11717,Q99720,Q14108,P20645,O15118,O15173,Q8WTV0,P02786,O75787,Q14739,Q5KU26,Q99523,P30825,P10586	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	154,2,255,37,252,199,8,409,296,416,396,114,54,119	932,1606,1072,252,199,296,3617,409,3218,750,1012,1790,3069,2511,119,1082,154,2760,942,37,562,54,889,2162,1893,1993,255,416,418,662,396,8,2103,114,3235,2,2120,1593,3432,3585,833,3381,1951	0.2857692407025649,-0.0012581004565036626,0.2224334357534765,1.08805639508316,1.327766595224347,0.9973494401983068,-2.342454069604444,0.7531817696547146,-0.7947358122572576,0.4117022638315761,0.25413257026133235,-0.06576592628969985,-0.6593637349435877,-0.3265940252928932,1.7982903969638317,0.2224334357534765,1.5350292358486646,-0.4587663248239629,0.2857692407025649,3.284999162596966,0.5677772700633923,2.707887319665007,0.31734400267200297,-0.19560956934146895,-0.098122333905974,-0.13054795621506413,1.08805639508316,0.7531817696547146,0.7531817696547146,0.47430803058067816,0.7838890695289682,5.940175937290734,-0.16304347134508207,1.8563207862044178,-0.7947358122572576,8.21990109917503,-0.16304347134508207,0.030894617027511038,-1.069696640684267,-1.6741333670170677,0.3803099800917596,-0.9659039071751861,-0.098122333905974	3643
Positive regulation of nf kappab transcription factor activity	11	32	2.847519541283169	0.0044061389020819	P19474,P02786,O60858,P14373,P05067,O75955,Q96HY6,P41440,P32929,Q13049,P60900	Processes and pathways	GO Biological process	msigdb_gobp	36,409,80,395,29,249,384,90,187,188,283	2050,1001,2502,80,249,409,29,2055,2511,1704,395,36,2225,437,1149,187,1296,90,3442,283,3118,1394,188,3122,2672,1315,1563,2460,572,1834,384,1431	-0.16304347134508207,0.25413257026133235,-0.3265940252928932,2.2579809707838456,1.118191455601226,0.7531817696547146,3.6353042018995785,-0.16304347134508207,-0.3265940252928932,-0.03347806686168351,0.7838890695289682,3.3662912544280115,-0.22824695247054547,0.7224199472328477,0.19067127264620573,1.387215394486587,0.12695555655645674,2.058127752852981,-1.104482929673742,1.027635769907882,-0.6930805097254553,0.09500082791205905,1.387215394486587,-0.6930805097254553,-0.3925286203228279,0.12695555655645674,0.030894617027511038,-0.29373844618932715,0.5677772700633923,-0.06576592628969985,0.8145422833591529,0.09500082791205905	3643
Transporter activity	44	217	2.8345040427857766	0.0045896877212261	Q9BSK2,Q86VD7,O15118,Q8WTV0,Q6NT16,Q96H78,Q8IXU6,O43772,Q01650,Q7L0J3,Q9H813,O75027,P39210,Q7KZN9,P11166,P21796,Q8N4V1,O95563,Q70HW3,Q9NWR8,Q9UBX3,Q9Y487,O43676,P53985,P16615,O75251,O14678,Q6P4Q7,Q8NHS3,Q9HD20,P30825,P03886,O15173,P00846,P45880,Q93050,O75964,P41440,Q9Y6M7,Q9H4L5,Q13423,P25705,O43681,O75380	Functions	GO Molecular function	msigdb_gomf	260,256,252,8,10,274,12,13,143,17,150,21,267,286,279,34,167,152,285,305,306,43,163,44,172,294,176,316,52,183,54,62,199,74,78,82,214,90,361,100,352,237,118,120	2751,2321,1208,3065,646,2408,453,2047,176,2793,1954,252,199,1003,1695,2411,163,3494,118,13,2754,2795,21,294,471,120,1006,3145,1450,1218,214,1698,1453,3146,651,2649,882,1372,940,152,792,500,2705,559,74,62,2967,703,1962,2054,3149,1873,2141,1012,3191,3106,1374,704,1618,1144,1291,279,2331,1145,2223,172,2869,3544,3071,1015,561,2061,3422,34,1797,2517,3112,237,1622,2971,3615,54,1713,2342,1226,1624,847,2661,267,90,78,1298,3487,2934,795,3263,459,3607,460,535,1980,2073,44,440,711,2522,1471,3159,2587,2807,351,1477,2163,2812,3079,143,2771,1028,506,352,1728,624,3301,963,1649,662,2603,2820,3042,2274,1657,10,2366,3456,719,316,285,286,17,256,2277,1177,12,671,167,1915,1501,2949,3525,52,573,2829,8,2103,82,1336,3634,3616,574,274,2906,2907,1674,1262,1263,2021,682,2737,2292,3179,577,260,3334,1347,984,2841,2115,549,2388,733,1350,100,150,1057,405,553,183,822,1193,2844,2120,2485,2912,3182,305,1432,2785,306,3463,991,2401,924,2788,2959,1596,2205,3380,43,2316,1859,1067,1280,693,694,3315,361,3537	-0.4587663248239629,-0.2609563355332265,0.15884550726049723,-0.6593637349435877,0.47430803058067816,-0.29373844618932715,0.6916031594494587,-0.16304347134508207,1.446478167816503,-0.4920008457387619,-0.13054795621506413,1.08805639508316,1.327766595224347,0.25413257026133235,-0.03347806686168351,-0.29373844618932715,1.5055575321040489,-1.244601121096576,1.7982903969638317,5.243267115697605,-0.4587663248239629,-0.4920008457387619,4.373525061543824,0.9973494401983068,0.6607309570482511,1.7692119702003737,0.25413257026133235,-0.726880811724572,0.06298071889501843,0.15884550726049723,1.2382387072449188,-0.03347806686168351,0.06298071889501843,-0.726880811724572,0.47430803058067816,-0.3925286203228279,0.31734400267200297,0.09500082791205905,0.2857692407025649,1.5350292358486646,0.3803099800917596,0.6298028841948623,-0.42560918711049844,0.5677772700633923,2.371337868662573,2.512197372488192,-0.5921770650124923,0.44303477605405855,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.098122333905974,-0.19560956934146895,0.25413257026133235,-0.7607655898218467,-0.6930805097254553,0.09500082791205905,0.44303477605405855,-0.0012581004565036626,0.19067127264620573,0.12695555655645674,1.027635769907882,-0.2609563355332265,0.19067127264620573,-0.22824695247054547,1.4760406150941263,-0.525313577596298,-1.421932600442622,-0.6593637349435877,0.25413257026133235,0.5677772700633923,-0.16304347134508207,-1.069696640684267,3.528055524230381,-0.06576592628969985,-0.3265940252928932,-0.6930805097254553,1.1482768495977804,-0.0012581004565036626,-0.5921770650124923,-2.2291720974867153,2.707887319665007,-0.03347806686168351,-0.2609563355332265,0.15884550726049723,-0.0012581004565036626,0.34885740302862467,-0.3925286203228279,1.0578712931665288,2.058127752852981,2.286376867508823,0.12695555655645674,-1.209424370050621,-0.5587053640309138,0.3803099800917596,-0.8287924672030076,0.6916031594494587,-2.042021033479733,0.6916031594494587,0.5988184783374502,-0.13054795621506413,-0.16304347134508207,3.1215736355280526,0.7224199472328477,0.44303477605405855,-0.3265940252928932,0.06298071889501843,-0.726880811724572,-0.3595238272390506,-0.4920008457387619,0.8756881681175116,0.06298071889501843,-0.19560956934146895,-0.4920008457387619,-0.6593637349435877,1.5938382520831849,-0.4587663248239629,0.25413257026133235,0.6298028841948623,0.8756881681175116,-0.03347806686168351,0.5055225334229401,-0.8629365633590367,0.2857692407025649,-0.0012581004565036626,0.47430803058067816,-0.3595238272390506,-0.4920008457387619,-0.6257295573052645,-0.22824695247054547,-0.0012581004565036626,5.593769792208002,-0.2609563355332265,-1.1393655482262741,0.44303477605405855,0.9670119136618348,1.027635769907882,1.027635769907882,4.734981990697083,1.08805639508316,-0.22824695247054547,0.19067127264620573,5.444068869967951,0.47430803058067816,1.5055575321040489,-0.098122333905974,0.06298071889501843,-0.5587053640309138,-1.315246174406957,2.818941470146897,0.5677772700633923,-0.4920008457387619,5.940175937290734,-0.16304347134508207,2.2010744460285183,0.12695555655645674,-4.5798467158688725,-2.2291720974867153,0.5677772700633923,1.0578712931665288,-0.525313577596298,-0.525313577596298,-0.0012581004565036626,0.15884550726049723,0.15884550726049723,-0.13054795621506413,0.47430803058067816,-0.42560918711049844,-0.22824695247054547,-0.726880811724572,0.5677772700633923,1.08805639508316,-0.8971691305719629,0.12695555655645674,0.2857692407025649,-0.4920008457387619,-0.16304347134508207,0.5988184783374502,-0.2609563355332265,0.44303477605405855,0.12695555655645674,1.9718833674139287,1.5644560394229112,0.25413257026133235,0.7838890695289682,0.5988184783374502,1.4168698692908286,0.3803099800917596,0.19067127264620573,-0.4920008457387619,-0.16304347134508207,-0.29373844618932715,-0.525313577596298,-0.726880811724572,0.9973494401983068,0.09500082791205905,-0.4587663248239629,0.9973494401983068,-1.1393655482262741,0.2857692407025649,-0.2609563355332265,0.31734400267200297,-0.4587663248239629,-0.5587053640309138,0.030894617027511038,-0.19560956934146895,-0.9659039071751861,3.2306497156014906,-0.22824695247054547,-0.06576592628969985,0.25413257026133235,0.15884550726049723,0.47430803058067816,0.47430803058067816,-0.8629365633590367,0.8756881681175116,-1.3507131280591325	3643
Serine hydrolase activity	9	22	2.8015429910639864	0.0050858864192633	Q9H3G5,Q9HB40,P42785,Q4J6C6,O75976,Q6PIU2,Q16740,O14773,P10619	Functions	GO Molecular function	msigdb_gomf	359,35,4,135,206,419,113,391,59	391,206,59,3109,2659,1973,4,3201,1980,1632,2254,113,1652,135,1042,3045,419,2005,2989,491,359,35	0.7838890695289682,1.2979715997804608,2.5402599154147643,-0.6930805097254553,-0.3925286203228279,-0.13054795621506413,6.233993929662534,-0.7607655898218467,-0.13054795621506413,-0.0012581004565036626,-0.22824695247054547,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,0.25413257026133235,-0.6257295573052645,0.7531817696547146,-0.13054795621506413,-0.5921770650124923,0.6607309570482511,0.8756881681175116,3.447308651903207	3643
Abnormality of the gallbladder	11	42	2.796019913153011	0.005173621260722	P22830,P04066,P07602,Q15056,Q15437,Q71SY5,O43681,O00192,Q9UBM7,O96028,Q9UIG0	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	0,228,69,462,110,144,118,389,289,87,527	2319,389,118,1610,1451,1372,87,703,228,2922,2509,69,2923,3023,1707,1878,2515,0,3199,1464,1298,1301,2157,2074,3408,1089,803,1562,462,110,569,144,3132,1334,2100,1048,2478,1064,289,527,2309,1603	-0.2609563355332265,0.7838890695289682,1.7982903969638317,-0.0012581004565036626,0.06298071889501843,0.09500082791205905,2.11542427763213,0.44303477605405855,1.1783129469800828,-0.5587053640309138,-0.3265940252928932,2.427791890653298,-0.5587053640309138,-0.6257295573052645,-0.03347806686168351,-0.098122333905974,-0.3265940252928932,9.72862962082004,-0.7607655898218467,0.06298071889501843,0.12695555655645674,0.12695555655645674,-0.19560956934146895,-0.16304347134508207,-1.0350054838275398,0.2224334357534765,0.3803099800917596,0.030894617027511038,0.6916031594494587,1.914184390727662,0.5677772700633923,1.5938382520831849,-0.6930805097254553,0.12695555655645674,-0.16304347134508207,0.25413257026133235,-0.29373844618932715,0.25413257026133235,1.027635769907882,0.6298028841948623,-0.22824695247054547,0.030894617027511038	3643
Platyspondyly	12	36	2.7906103436537486	0.0052608764497323	P16278,O00754,P04066,Q8WVQ1,Q96L58,Q7RTS9,Q14739,O95831,P08236,Q96HY6,P00813,P48735	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,435,228,423,303,11,416,47,455,384,56,339	3186,435,1958,2412,1284,3288,47,56,228,455,155,2337,2516,2147,1881,707,339,1886,1026,2257,1989,416,900,2728,1246,2366,1905,11,909,423,1112,384,303,3096,524,2312	-0.7607655898218467,0.7224199472328477,-0.13054795621506413,-0.29373844618932715,0.12695555655645674,-0.8629365633590367,3.0119856905575273,2.6800374279695216,1.1783129469800828,0.6916031594494587,1.5350292358486646,-0.2609563355332265,-0.3265940252928932,-0.19560956934146895,-0.098122333905974,0.44303477605405855,0.9061816816409076,-0.098122333905974,0.25413257026133235,-0.22824695247054547,-0.13054795621506413,0.7531817696547146,0.31734400267200297,-0.42560918711049844,0.15884550726049723,-0.2609563355332265,-0.098122333905974,5.543953911878619,0.31734400267200297,0.7531817696547146,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.6593637349435877,0.6298028841948623,-0.22824695247054547	3643
Azurophil granule	20	75	2.7903332628121253	0.0052653812859619	P78371,P42785,P10253,P06280,P16278,Q07065,P15586,Q92542,P10619,O00754,P07602,P08236,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q9NQX7	Localization	GO Cellular component	msigdb_gocc	378,4,266,153,155,173,410,317,59,435,69,455,228,103,351,108,115,112,118,122	2322,103,435,108,586,118,2700,1078,1456,2704,228,153,1013,3191,1701,69,3538,455,266,59,3219,1964,1082,2332,112,410,155,2869,3294,563,3197,3324,707,3200,4,2935,2237,3265,1300,476,1805,1632,1806,2349,1023,351,2161,378,2813,2938,173,1238,2087,2532,2001,1663,1916,317,1417,1835,1507,2111,3179,683,115,3211,2115,2693,122,2912,2202,1064,1199,2492,609	-0.2609563355332265,1.943054324684516,0.7224199472328477,1.914184390727662,0.5366787829519797,1.7982903969638317,-0.42560918711049844,0.2224334357534765,0.06298071889501843,-0.42560918711049844,1.1783129469800828,1.5350292358486646,0.25413257026133235,-0.7607655898218467,-0.03347806686168351,2.427791890653298,-1.3862754857551036,0.6916031594494587,1.0578712931665288,2.5402599154147643,-0.7947358122572576,-0.13054795621506413,0.2224334357534765,-0.2609563355332265,1.8563207862044178,0.7531817696547146,1.5350292358486646,-0.525313577596298,-0.8629365633590367,0.5677772700633923,-0.7607655898218467,-0.8971691305719629,0.44303477605405855,-0.7607655898218467,6.233993929662534,-0.5587053640309138,-0.22824695247054547,-0.8287924672030076,0.12695555655645674,0.6607309570482511,-0.06576592628969985,-0.0012581004565036626,-0.06576592628969985,-0.2609563355332265,0.25413257026133235,0.8756881681175116,-0.19560956934146895,0.8145422833591529,-0.4920008457387619,-0.5587053640309138,1.4760406150941263,0.15884550726049723,-0.16304347134508207,-0.3265940252928932,-0.13054795621506413,-0.0012581004565036626,-0.098122333905974,0.9670119136618348,0.09500082791205905,-0.06576592628969985,0.06298071889501843,-0.16304347134508207,-0.726880811724572,0.47430803058067816,1.8563207862044178,-0.7607655898218467,-0.16304347134508207,-0.3925286203228279,1.7692119702003737,-0.525313577596298,-0.19560956934146895,0.25413257026133235,0.19067127264620573,-0.29373844618932715,0.5366787829519797	3643
Transport of small molecules	39	171	2.788968201314301	0.0052876256423384	O15118,Q8WTV0,P20618,P30519,Q01650,O75027,P28072,P60900,P11166,P21796,Q8N4V1,O00231,Q70HW3,Q9UBX3,Q9NWR8,Q9Y487,P28074,P28070,P53985,P16615,P02786,Q6PIU2,Q9HD20,Q9UBI6,P30825,Q9BPX6,P49721,P55011,P45880,P51790,Q93050,P51798,Q9Y6M7,P61916,Q13555,Q9UNS2,Q9H4I9,Q99436,Q8IYU8	Processes and pathways	Reactome Pathways	msigdb_reactome	252,8,137,14,143,21,146,283,279,34,167,278,285,306,305,43,41,164,44,172,409,419,183,451,54,320,60,440,78,459,82,460,361,351,105,106,244,121,257	278,3316,3249,646,1135,3142,252,1003,1609,21,2137,3144,1615,3254,2417,2798,1372,2328,3617,1787,409,1962,2054,3149,1873,1010,3150,1374,704,1702,653,1377,279,2331,1145,751,172,3406,2577,1015,2514,137,2061,3422,1795,34,2517,2762,1461,1621,2802,563,3222,164,146,41,1622,14,3424,54,2342,2229,1225,846,889,3425,2932,1624,3578,2661,1464,1975,3034,78,2153,2878,60,1229,459,3607,460,2348,44,3075,440,3267,2349,283,949,2587,351,3163,2523,3078,2251,3202,1477,1392,952,143,3269,658,1561,2985,1093,2672,105,2597,3540,1485,963,662,965,3042,1041,3456,419,285,1741,1177,257,167,1745,2949,3525,573,2829,8,2468,2013,2284,82,1050,2907,1264,121,1507,3235,2737,2292,320,2113,3056,2841,2115,491,3533,244,183,822,1193,2844,2485,305,451,741,306,526,2401,2308,554,2788,2563,106,2205,43,608,1280,694,876,361	1.027635769907882,-0.8971691305719629,-0.8287924672030076,0.47430803058067816,0.19067127264620573,-0.726880811724572,1.08805639508316,0.25413257026133235,-0.0012581004565036626,4.373525061543824,-0.19560956934146895,-0.726880811724572,-0.0012581004565036626,-0.8287924672030076,-0.29373844618932715,-0.4920008457387619,0.09500082791205905,-0.2609563355332265,-2.342454069604444,-0.06576592628969985,0.7531817696547146,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.098122333905974,0.25413257026133235,-0.726880811724572,0.09500082791205905,0.44303477605405855,-0.03347806686168351,0.47430803058067816,0.09500082791205905,1.027635769907882,-0.2609563355332265,0.19067127264620573,0.4117022638315761,1.4760406150941263,-1.0350054838275398,-0.3595238272390506,0.25413257026133235,-0.3265940252928932,1.623176179314646,-0.16304347134508207,-1.069696640684267,-0.06576592628969985,3.528055524230381,-0.3265940252928932,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,0.5677772700633923,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.0012581004565036626,5.1928477731586264,-1.069696640684267,2.707887319665007,-0.2609563355332265,-0.22824695247054547,0.15884550726049723,0.34885740302862467,0.31734400267200297,-1.069696640684267,-0.5587053640309138,-0.0012581004565036626,-1.63783022894056,-0.3925286203228279,0.06298071889501843,-0.13054795621506413,-0.6257295573052645,2.286376867508823,-0.19560956934146895,-0.525313577596298,2.5402599154147643,0.15884550726049723,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.2609563355332265,3.1215736355280526,-0.6593637349435877,0.7224199472328477,-0.8287924672030076,-0.2609563355332265,1.027635769907882,0.2857692407025649,-0.3595238272390506,0.8756881681175116,-0.726880811724572,-0.3265940252928932,-0.6593637349435877,-0.22824695247054547,-0.7607655898218467,0.06298071889501843,0.09500082791205905,0.2857692407025649,1.5938382520831849,-0.8287924672030076,0.47430803058067816,0.030894617027511038,-0.5921770650124923,0.2224334357534765,-0.3925286203228279,1.943054324684516,-0.3595238272390506,-1.3862754857551036,0.06298071889501843,0.2857692407025649,0.47430803058067816,0.2857692407025649,-0.6257295573052645,0.25413257026133235,-1.1393655482262741,0.7531817696547146,1.027635769907882,-0.03347806686168351,0.19067127264620573,1.08805639508316,1.5055575321040489,-0.03347806686168351,-0.5587053640309138,-1.315246174406957,0.5677772700633923,-0.4920008457387619,5.940175937290734,-0.29373844618932715,-0.13054795621506413,-0.22824695247054547,2.2010744460285183,0.25413257026133235,-0.525313577596298,0.15884550726049723,1.7692119702003737,0.06298071889501843,-0.7947358122572576,-0.42560918711049844,-0.22824695247054547,0.9670119136618348,-0.16304347134508207,-0.6257295573052645,-0.4920008457387619,-0.16304347134508207,0.6607309570482511,-1.3507131280591325,1.1482768495977804,1.4168698692908286,0.3803099800917596,0.19067127264620573,-0.4920008457387619,-0.29373844618932715,0.9973494401983068,0.7224199472328477,0.44303477605405855,0.9973494401983068,0.6298028841948623,-0.2609563355332265,-0.22824695247054547,0.5988184783374502,-0.4587663248239629,-0.3265940252928932,1.943054324684516,-0.19560956934146895,3.2306497156014906,0.5366787829519797,0.15884550726049723,0.47430803058067816,0.34885740302862467,0.8756881681175116	3643
Anion transport	31	84	2.781915897093492	0.0054039041952496	Q14728,Q86VD7,P14174,Q01650,Q7L0J3,Q9H813,Q9HC21,Q9Y619,Q9Y666,Q9UHG3,P11166,P21796,O00400,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,P80404,Q15758,P30825,O43865,P55011,Q9H2D1,P07602,P45880,P51790,P51798,P41440,Q9Y6M7,O43681	Processes and pathways	GO Biological process	msigdb_gobp	624,256,15,143,17,150,553,693,694,430,279,34,646,152,306,577,44,573,413,662,54,55,440,733,69,78,459,460,90,361,118	3065,646,2793,2049,1003,118,2754,55,2219,1450,3068,152,2508,1962,1873,3218,69,1374,704,1144,3219,279,2331,1145,15,34,1622,3615,54,2342,90,78,459,3607,460,2073,44,1555,440,413,2812,143,2771,1395,2672,624,1317,765,963,662,3124,3042,2274,1657,2366,3456,17,256,1177,573,2829,2906,2907,1262,2292,577,2841,1424,733,150,1057,553,1844,1432,1064,306,430,924,2205,2640,693,694,3315,361	-0.6593637349435877,0.47430803058067816,-0.4920008457387619,-0.16304347134508207,0.25413257026133235,1.7982903969638317,-0.4587663248239629,2.6800374279695216,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.3265940252928932,-0.13054795621506413,-0.098122333905974,-0.7947358122572576,2.427791890653298,0.09500082791205905,0.44303477605405855,0.19067127264620573,-0.7947358122572576,1.027635769907882,-0.2609563355332265,0.19067127264620573,4.964849362308119,3.528055524230381,-0.0012581004565036626,-2.2291720974867153,2.707887319665007,-0.2609563355332265,2.058127752852981,2.286376867508823,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.16304347134508207,3.1215736355280526,0.030894617027511038,0.7224199472328477,0.7531817696547146,-0.4920008457387619,1.5938382520831849,-0.4587663248239629,0.09500082791205905,-0.3925286203228279,0.5055225334229401,0.12695555655645674,0.4117022638315761,0.2857692407025649,0.47430803058067816,-0.6930805097254553,-0.6257295573052645,-0.22824695247054547,-0.0012581004565036626,-0.2609563355332265,-1.1393655482262741,4.734981990697083,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.15884550726049723,-0.22824695247054547,0.5677772700633923,-0.4920008457387619,0.09500082791205905,0.44303477605405855,1.5644560394229112,0.25413257026133235,0.5988184783374502,-0.06576592628969985,0.09500082791205905,0.25413257026133235,0.9973494401983068,0.7531817696547146,0.31734400267200297,-0.19560956934146895,-0.3595238272390506,0.47430803058067816,0.47430803058067816,-0.8629365633590367,0.8756881681175116	3643
Carboxylic acid transport	7	38	2.7627288877296485	0.0057320356180525	P07602,P53985,P14174,Q01650,Q7L0J3,P30825,P41440	Processes and pathways	GO Biological process	msigdb_gobp	69,44,15,143,17,54,90	2793,2049,1003,2219,1450,3068,152,2508,3218,69,704,15,1622,54,2342,90,2073,44,440,413,143,2771,1317,765,662,3456,17,1177,2829,2906,2907,577,733,1057,1064,306,924,693	-0.4920008457387619,-0.16304347134508207,0.25413257026133235,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.3265940252928932,-0.7947358122572576,2.427791890653298,0.44303477605405855,4.964849362308119,-0.0012581004565036626,2.707887319665007,-0.2609563355332265,2.058127752852981,-0.16304347134508207,3.1215736355280526,0.7224199472328477,0.7531817696547146,1.5938382520831849,-0.4587663248239629,0.12695555655645674,0.4117022638315761,0.47430803058067816,-1.1393655482262741,4.734981990697083,0.19067127264620573,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816	3643
Sensorimotor neuropathy	13	40	2.757459445583457	0.0058252438628378	Q9NR77,P03886,O60313,P07602,P00846,Q7LG56,O95831,Q5KU26,P39210,P41440,Q9Y2R0,P07196,P00403	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,62,529,69,74,464,47,396,267,90,219,125,559	1605,2212,529,1616,47,2705,559,74,62,2967,2054,125,69,1221,2065,1971,2711,267,2232,90,1885,2238,2242,2349,2880,1238,3328,2091,396,668,464,859,813,2622,1053,32,3006,1064,219,608	-0.0012581004565036626,-0.22824695247054547,0.5988184783374502,-0.0012581004565036626,3.0119856905575273,-0.42560918711049844,0.5677772700633923,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.16304347134508207,1.7400910153055076,2.427791890653298,0.15884550726049723,-0.16304347134508207,-0.13054795621506413,-0.42560918711049844,1.0578712931665288,-0.22824695247054547,2.058127752852981,-0.098122333905974,-0.22824695247054547,-0.22824695247054547,-0.2609563355332265,-0.525313577596298,0.15884550726049723,-0.8971691305719629,-0.16304347134508207,0.7838890695289682,0.47430803058067816,0.6916031594494587,0.34885740302862467,0.3803099800917596,-0.3595238272390506,0.25413257026133235,3.6085359292973544,-0.5921770650124923,0.25413257026133235,1.2382387072449188,0.5366787829519797	3643
Regulation of lymphocyte activation	8	58	2.755988875979018	0.0058514987010116	Q9NUQ9,Q9HCL2,P22466,P14174,P12956,P30825,P00813,O96028	Processes and pathways	GO Biological process	msigdb_gobp	102,5,38,15,83,54,56,87	1952,2792,2410,2215,2860,3365,87,2757,56,409,2508,590,1081,1377,3256,1082,83,15,3629,1084,38,437,138,54,592,2874,708,1547,1548,3440,3344,1390,3038,1815,1395,2526,2267,1315,1404,1100,2535,969,1737,468,2015,978,2619,681,914,1339,2621,1928,5,492,638,102,2788,555	-0.13054795621506413,-0.4920008457387619,-0.29373844618932715,-0.22824695247054547,-0.525313577596298,-0.9659039071751861,2.11542427763213,-0.4587663248239629,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,0.09500082791205905,-0.8287924672030076,0.2224334357534765,2.172563346869744,4.964849362308119,-2.997816021189173,0.2224334357534765,3.257840018273795,0.7224199472328477,1.623176179314646,2.707887319665007,0.5366787829519797,-0.525313577596298,0.44303477605405855,0.030894617027511038,0.030894617027511038,-1.104482929673742,-0.931491220478586,0.09500082791205905,-0.6257295573052645,-0.06576592628969985,0.09500082791205905,-0.3265940252928932,-0.22824695247054547,0.12695555655645674,0.09500082791205905,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.6916031594494587,-0.13054795621506413,0.2857692407025649,-0.3595238272390506,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.3595238272390506,-0.098122333905974,6.233993929662534,0.6607309570482511,0.5055225334229401,1.9718833674139287,-0.4587663248239629,0.5988184783374502	3643
Organic acid transmembrane transport	10	35	2.751664881363741	0.0059293162888811	P11166,O95563,Q9UBX3,P23786,P53985,O43772,Q01650,O14678,P30825,P41440	Processes and pathways	GO Biological process	msigdb_gobp	279,152,306,200,44,13,143,176,54,90	176,13,2219,1450,3068,152,3218,1374,704,279,200,1622,54,592,364,1224,2342,90,3264,2073,44,143,2771,1317,662,1177,2829,2906,2907,577,733,1057,306,924,693	1.446478167816503,5.243267115697605,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.7947358122572576,0.09500082791205905,0.44303477605405855,1.027635769907882,1.327766595224347,-0.0012581004565036626,2.707887319665007,0.5366787829519797,0.845141841466991,0.15884550726049723,-0.2609563355332265,2.058127752852981,-0.8287924672030076,-0.16304347134508207,3.1215736355280526,1.5938382520831849,-0.4587663248239629,0.12695555655645674,0.47430803058067816,0.19067127264620573,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816	3643
Membrane lipid metabolic process	13	44	2.7454731332926507	0.0060423714727066	P16278,P04066,P07602,Q8NBX0,P50897,Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q969N2,Q96G23,P06280	Processes and pathways	GO Biological process	msigdb_gobp	155,228,69,331,72,330,28,85,251,227,318,159,153	746,2212,2216,85,1777,701,703,228,153,1013,69,3538,155,2869,1797,502,1968,72,2938,2166,3473,330,1900,905,569,809,331,28,1921,318,159,2020,1117,426,2388,227,251,1758,2488,1432,1064,2847,1199,2565	0.4117022638315761,-0.22824695247054547,-0.22824695247054547,2.144013371443563,-0.06576592628969985,0.44303477605405855,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,1.5350292358486646,-0.525313577596298,-0.06576592628969985,0.6298028841948623,-0.13054795621506413,2.399583395405736,-0.5587053640309138,-0.19560956934146895,-1.174345720866778,0.9366227945511973,-0.098122333905974,0.31734400267200297,0.5677772700633923,0.3803099800917596,0.9366227945511973,3.768713037747525,-0.098122333905974,0.9670119136618348,1.5350292358486646,-0.13054795621506413,0.2224334357534765,0.7531817696547146,-0.2609563355332265,1.2083001127798034,1.118191455601226,-0.03347806686168351,-0.29373844618932715,0.09500082791205905,0.25413257026133235,-0.4920008457387619,0.19067127264620573,-0.3265940252928932	3643
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	8	20	2.743230242451003	0.0060838011633934	Q02818,P07942,Q06481,Q8NBJ4,Q07065,O43493,Q9BTY2,P05067	Processes and pathways	Reactome Pathways	msigdb_reactome	65,126,39,75,173,142,115,29	142,2698,881,29,3150,126,3257,1706,2513,843,65,39,173,1238,2448,3583,1246,301,75,115	1.5938382520831849,-0.42560918711049844,0.31734400267200297,3.6353042018995785,-0.726880811724572,1.7109272480905777,-0.8287924672030076,-0.03347806686168351,-0.3265940252928932,0.34885740302862467,2.4840986629825825,3.257840018273795,1.4760406150941263,0.15884550726049723,-0.29373844618932715,-1.6741333670170677,0.15884550726049723,0.9973494401983068,2.371337868662573,1.8563207862044178	3643
Secretory granule membrane	14	75	2.739837246021364	0.0061469615209248	P11717,P42785,P07602,Q9NQX7,Q06481,P84095,O15260,O75787,P30519,Q07065,Q93050,P15291,P10253,O75592	Localization	GO Cellular component	msigdb_gocc	154,4,69,122,39,139,108,296,14,173,82,112,266,186	932,108,1003,789,1534,1613,2700,1078,186,296,2798,1456,1872,1012,69,266,532,3219,1082,154,2332,112,3552,1084,560,563,14,3424,2343,889,3200,4,709,795,1300,2156,476,2241,596,1890,2075,3268,1156,3120,139,39,173,1395,2528,3348,2598,1315,3611,3042,2604,667,2001,1909,1916,973,317,82,482,3447,3179,1933,2115,1354,122,2912,1064,1199,1599,1280,1860	0.2857692407025649,1.914184390727662,0.25413257026133235,0.3803099800917596,0.030894617027511038,-0.0012581004565036626,-0.42560918711049844,0.2224334357534765,1.387215394486587,0.9973494401983068,-0.4920008457387619,0.06298071889501843,-0.098122333905974,0.25413257026133235,2.427791890653298,1.0578712931665288,0.5988184783374502,-0.7947358122572576,0.2224334357534765,1.5350292358486646,-0.2609563355332265,1.8563207862044178,-1.4576838354723742,0.2224334357534765,0.5677772700633923,0.5677772700633923,5.1928477731586264,-1.069696640684267,-0.2609563355332265,0.31734400267200297,-0.7607655898218467,6.233993929662534,0.44303477605405855,0.3803099800917596,0.12695555655645674,-0.19560956934146895,0.6607309570482511,-0.22824695247054547,0.5366787829519797,-0.098122333905974,-0.16304347134508207,-0.8287924672030076,0.19067127264620573,-0.6930805097254553,1.623176179314646,3.257840018273795,1.4760406150941263,0.09500082791205905,-0.3265940252928932,-0.931491220478586,-0.3595238272390506,0.12695555655645674,-2.1540615170130093,-0.6257295573052645,-0.3595238272390506,0.47430803058067816,-0.13054795621506413,-0.098122333905974,-0.098122333905974,0.2857692407025649,0.9670119136618348,2.2010744460285183,0.6607309570482511,-1.104482929673742,-0.726880811724572,-0.098122333905974,-0.16304347134508207,0.12695555655645674,1.7692119702003737,-0.525313577596298,0.25413257026133235,0.19067127264620573,0.030894617027511038,0.15884550726049723,-0.06576592628969985	3643
Slowly progressive	12	58	2.731523251411245	0.0063042292417956	Q9NR77,Q99720,Q8IV08,O00584,O75787,O95831,P02545,O43707,O14773,P41440,Q13049,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,73,103,296,47,265,325,391,90,188,125	1605,103,391,1000,2571,325,2136,3404,296,2417,791,47,265,2054,125,2331,1876,2064,1295,1971,2711,2662,90,2432,946,849,1155,1301,1387,2585,188,415,2087,2529,477,2091,1039,1320,3043,3502,2452,2729,2946,73,859,813,2830,3177,2,2112,1581,3533,32,1849,1850,2785,2960,608	-0.0012581004565036626,1.943054324684516,0.7838890695289682,0.25413257026133235,-0.3595238272390506,0.9366227945511973,-0.19560956934146895,-1.0350054838275398,0.9973494401983068,-0.29373844618932715,0.3803099800917596,3.0119856905575273,1.0578712931665288,-0.16304347134508207,1.7400910153055076,-0.2609563355332265,-0.098122333905974,-0.16304347134508207,0.12695555655645674,-0.13054795621506413,-0.42560918711049844,-0.3925286203228279,2.058127752852981,-0.29373844618932715,0.2857692407025649,0.34885740302862467,0.19067127264620573,0.12695555655645674,0.09500082791205905,-0.3595238272390506,1.387215394486587,0.7531817696547146,-0.16304347134508207,-0.3265940252928932,0.6607309570482511,-0.16304347134508207,0.25413257026133235,0.12695555655645674,-0.6257295573052645,-1.244601121096576,-0.29373844618932715,-0.42560918711049844,-0.5587053640309138,2.399583395405736,0.34885740302862467,0.3803099800917596,-0.4920008457387619,-0.726880811724572,8.21990109917503,-0.16304347134508207,0.030894617027511038,-1.3507131280591325,3.6085359292973544,-0.06576592628969985,-0.06576592628969985,-0.4587663248239629,-0.5587053640309138,0.5366787829519797	3643
Apical plasma membrane	15	54	2.725438442836169	0.0064216149623532	P11166,P55011,P26038,P53985,O75787,Q01650,P51790,Q9Y4G8,O14523,P30825,O43865,P78536,O75955,P41440,Q9Y6M7	Localization	GO Cellular component	msigdb_gocc	279,440,501,44,296,143,459,81,453,54,55,216,249,90,361	1770,1207,453,2793,2571,1003,55,1367,296,249,2508,1962,2054,3149,1374,704,2923,1457,279,3321,941,843,1015,2061,2517,501,54,2342,2068,1624,1544,2661,90,459,44,3075,440,2587,216,143,2443,1315,963,1650,541,2460,2737,2292,1354,2695,2912,1520,81,361	-0.06576592628969985,0.15884550726049723,0.6916031594494587,-0.4920008457387619,-0.3595238272390506,0.25413257026133235,2.6800374279695216,0.09500082791205905,0.9973494401983068,1.118191455601226,-0.3265940252928932,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,0.09500082791205905,0.44303477605405855,-0.5587053640309138,0.06298071889501843,1.027635769907882,-0.8971691305719629,0.2857692407025649,0.34885740302862467,0.25413257026133235,-0.16304347134508207,-0.3265940252928932,0.6298028841948623,2.707887319665007,-0.2609563355332265,-0.16304347134508207,-0.0012581004565036626,0.030894617027511038,-0.3925286203228279,2.058127752852981,0.6916031594494587,3.1215736355280526,-0.6593637349435877,0.7224199472328477,-0.3595238272390506,1.2382387072449188,1.5938382520831849,-0.29373844618932715,0.12695555655645674,0.2857692407025649,-0.0012581004565036626,0.5988184783374502,-0.29373844618932715,-0.42560918711049844,-0.22824695247054547,0.12695555655645674,-0.3925286203228279,-0.525313577596298,0.06298071889501843,2.2579809707838456,0.8756881681175116	3643
Cell recognition	6	26	2.712014803345136	0.0066875606168268	P78371,Q9BY67,Q8WTV0,P45880,P15291,P05067	Processes and pathways	GO Biological process	msigdb_gobp	378,304,8,78,112,29	1606,2409,2922,29,112,1084,2334,501,889,78,1467,1468,2237,1470,2437,378,1647,396,3305,8,1184,2377,1342,304,1847,1443	-0.0012581004565036626,-0.29373844618932715,-0.5587053640309138,3.6353042018995785,1.8563207862044178,0.2224334357534765,-0.2609563355332265,0.6298028841948623,0.31734400267200297,2.286376867508823,0.06298071889501843,0.06298071889501843,-0.22824695247054547,0.06298071889501843,-0.29373844618932715,0.8145422833591529,-0.0012581004565036626,0.7838890695289682,-0.8629365633590367,5.940175937290734,0.19067127264620573,-0.2609563355332265,0.12695555655645674,0.9973494401983068,-0.06576592628969985,0.09500082791205905	3643
Transmembrane receptor protein serine threonine kinase signaling pathway	12	54	2.705191192284207	0.0068265086404599	Q8WUH2,P49354,Q06481,Q92896,Q9UIQ6,Q8N0X7,P08670,Q01082,Q8N3R9,Q13573,Q8N1F7,P78536	Processes and pathways	GO Biological process	msigdb_gobp	133,229,39,136,42,421,104,365,148,88,342,216	646,2322,2049,2502,1288,3218,1457,104,1791,1459,3322,3520,1384,1296,229,1155,3299,2436,1025,216,365,1893,2081,39,1994,2671,88,1484,1163,2270,2271,1097,1098,419,1909,421,342,148,1664,133,136,2378,1049,1923,1261,2023,2026,42,2562,1855,3138,744,2406,1132	0.47430803058067816,-0.2609563355332265,-0.16304347134508207,-0.3265940252928932,0.12695555655645674,-0.7947358122572576,0.06298071889501843,1.943054324684516,-0.06576592628969985,0.06298071889501843,-0.8971691305719629,-1.315246174406957,0.09500082791205905,0.12695555655645674,1.1783129469800828,0.19067127264620573,-0.8629365633590367,-0.29373844618932715,0.25413257026133235,1.2382387072449188,0.845141841466991,-0.098122333905974,-0.16304347134508207,3.257840018273795,-0.13054795621506413,-0.3925286203228279,2.11542427763213,0.06298071889501843,0.19067127264620573,-0.22824695247054547,-0.22824695247054547,0.2224334357534765,0.2224334357534765,0.7531817696547146,-0.098122333905974,0.7531817696547146,0.9061816816409076,1.5644560394229112,-0.0012581004565036626,1.6817203809689008,1.6524701228970238,-0.2609563355332265,0.25413257026133235,-0.098122333905974,0.15884550726049723,-0.13054795621506413,-0.13054795621506413,3.2306497156014906,-0.3265940252928932,-0.06576592628969985,-0.6930805097254553,0.44303477605405855,-0.2609563355332265,0.2224334357534765	3643
Parkinsonism	9	31	2.6993254929572488	0.006948018401623	Q99720,P07602,O75569,O96008,O75787,Q14203,Q9Y4W6,Q96RR1,P05067	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,69,350,500,296,415,608,319,29	1078,350,296,500,703,29,69,591,2225,1713,754,1301,2242,2349,1984,2721,955,1895,1992,415,963,1827,2624,1675,319,3177,2,1064,2562,1690,608	0.2224334357534765,0.8756881681175116,0.9973494401983068,0.6298028841948623,0.44303477605405855,3.6353042018995785,2.427791890653298,0.5366787829519797,-0.22824695247054547,-0.03347806686168351,0.4117022638315761,0.12695555655645674,-0.22824695247054547,-0.2609563355332265,-0.13054795621506413,-0.42560918711049844,0.2857692407025649,-0.098122333905974,-0.13054795621506413,0.7531817696547146,0.2857692407025649,-0.06576592628969985,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,-0.726880811724572,8.21990109917503,0.25413257026133235,-0.3265940252928932,-0.0012581004565036626,0.5366787829519797	3643
Peripheral demyelination	7	19	2.695275265163081	0.007033050318038	Q9NR77,P20700,P03886,P07602,P00846,O43681,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,310,62,69,74,118,125	118,74,62,2967,125,69,591,1878,310,1882,1155,3471,365,3091,32,1357,1064,1272,1279	1.7982903969638317,2.371337868662573,2.512197372488192,-0.5921770650124923,1.7400910153055076,2.427791890653298,0.5366787829519797,-0.098122333905974,0.9670119136618348,-0.098122333905974,0.19067127264620573,-1.174345720866778,0.845141841466991,-0.6593637349435877,3.6085359292973544,0.12695555655645674,0.25413257026133235,0.15884550726049723,0.15884550726049723	3643
Endocytosis	35	139	2.687989807314321	0.0071883590830934	Q14108,Q08380,O15118,Q8WTV0,P84095,Q5KU26,O14976,O00291,Q5VW38,P05067,P35579,P11717,P20645,Q06481,P02786,Q96ED9,Q9BZG1,Q14457,Q9NZM3,P50897,Q96RU3,Q13464,P51790,P30533,Q9NPF0,P41440,Q9H223,Q14185,Q15075,Q9Y5X1,O15260,Q99523,P57105,O75955,Q9NUN5	Processes and pathways	GO Biological process	msigdb_gobp	255,254,252,8,139,396,392,390,23,29,280,154,37,39,409,179,448,189,336,72,204,328,459,457,492,90,490,94,354,107,108,114,238,249,123	1206,390,1605,834,2322,3610,392,252,108,2860,588,1367,1078,249,2798,2328,3617,1787,409,29,3218,1012,3191,1702,1703,3572,1704,154,941,3024,942,1084,1794,1879,2578,37,3322,1711,3197,457,3520,280,90,655,1155,72,1300,2156,459,476,2348,238,1723,596,3571,1809,3077,1557,1389,1156,2251,139,3079,952,2813,39,955,3270,254,540,328,2596,1030,3348,255,2267,94,1402,189,2088,2089,2530,354,2269,1166,2727,3083,3042,1246,396,2093,23,3305,2946,1494,1411,1329,1915,3355,3597,8,2377,1050,3518,179,204,114,2687,1676,448,490,3003,1937,492,2554,123,3313,2307,336,872,1944,2957,3604,2401,3098,3063,2958,1854,3609,1595,3285,1596,743,1436,1204,107,2407,1525,583	0.15884550726049723,0.7838890695289682,-0.0012581004565036626,0.34885740302862467,-0.2609563355332265,-2.1540615170130093,0.7838890695289682,1.08805639508316,1.914184390727662,-0.525313577596298,0.5366787829519797,0.09500082791205905,0.2224334357534765,1.118191455601226,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,-0.06576592628969985,0.7531817696547146,3.6353042018995785,-0.7947358122572576,0.25413257026133235,-0.7607655898218467,-0.03347806686168351,-0.03347806686168351,-1.6016175956969314,-0.03347806686168351,1.5350292358486646,0.2857692407025649,-0.6257295573052645,0.2857692407025649,0.2224334357534765,-0.06576592628969985,-0.098122333905974,-0.3595238272390506,3.284999162596966,-0.8971691305719629,-0.03347806686168351,-0.7607655898218467,0.6916031594494587,-1.315246174406957,1.027635769907882,2.058127752852981,0.47430803058067816,0.19067127264620573,2.399583395405736,0.12695555655645674,-0.19560956934146895,0.6916031594494587,0.6607309570482511,-0.2609563355332265,1.1482768495977804,-0.03347806686168351,0.5366787829519797,-1.5654960467228805,-0.06576592628969985,-0.6593637349435877,0.030894617027511038,0.09500082791205905,0.19067127264620573,-0.22824695247054547,1.623176179314646,-0.6593637349435877,0.2857692407025649,-0.4920008457387619,3.257840018273795,0.2857692407025649,-0.8287924672030076,1.08805639508316,0.5988184783374502,0.9366227945511973,-0.3595238272390506,0.25413257026133235,-0.931491220478586,1.08805639508316,-0.22824695247054547,2.0006717808585845,0.09500082791205905,1.387215394486587,-0.16304347134508207,-0.16304347134508207,-0.3265940252928932,0.8756881681175116,-0.22824695247054547,0.19067127264620573,-0.42560918711049844,-0.6593637349435877,-0.6257295573052645,0.15884550726049723,0.7838890695289682,-0.16304347134508207,4.295431147653506,-0.8629365633590367,-0.5587053640309138,0.06298071889501843,0.09500082791205905,0.12695555655645674,-0.098122333905974,-0.931491220478586,-1.820239680626571,5.940175937290734,-0.2609563355332265,0.25413257026133235,-1.2798752825252815,1.446478167816503,1.327766595224347,1.8563207862044178,-0.3925286203228279,-0.0012581004565036626,0.7224199472328477,0.6607309570482511,-0.5921770650124923,-0.098122333905974,0.6607309570482511,-0.3265940252928932,1.7692119702003737,-0.8629365633590367,-0.22824695247054547,0.9366227945511973,0.34885740302862467,-0.098122333905974,-0.5587053640309138,-1.8938214246167355,-0.2609563355332265,-0.6593637349435877,-0.6257295573052645,-0.5587053640309138,-0.06576592628969985,-2.042021033479733,0.030894617027511038,-0.8287924672030076,0.030894617027511038,0.44303477605405855,0.09500082791205905,0.19067127264620573,1.943054324684516,-0.2609563355332265,0.06298071889501843,0.5677772700633923	3643
Abnormal muscle fiber morphology	22	75	2.676117054543415	0.0074480627116897	Q99720,P51114,O96008,P02545,P06753,P05067,P13807,O60313,Q70HW3,O43676,Q7Z406,O95831,Q9BPX6,Q96RR1,Q13049,P00403,P03886,P23786,P00846,Q7LG56,Q9H9S5,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,504,500,265,394,29,533,529,285,163,300,47,320,319,188,559,62,200,74,464,347,125	2408,2049,1000,163,1776,529,2136,3404,2647,47,500,2705,559,74,265,62,2967,2922,29,394,125,2923,1376,3257,2331,533,2927,944,200,753,754,2662,890,2432,849,1155,504,3607,2073,1022,2242,2349,1809,1989,2358,188,959,2087,2529,1096,807,3043,285,464,2606,300,3047,2898,2538,2734,976,1675,319,2,320,1581,3181,733,347,2305,2789,2960,608,1604,1068	-0.29373844618932715,-0.16304347134508207,0.25413257026133235,1.5055575321040489,-0.06576592628969985,0.5988184783374502,-0.19560956934146895,-1.0350054838275398,-0.3925286203228279,3.0119856905575273,0.6298028841948623,-0.42560918711049844,0.5677772700633923,2.371337868662573,1.0578712931665288,2.512197372488192,-0.5921770650124923,-0.5587053640309138,3.6353042018995785,0.7838890695289682,1.7400910153055076,-0.5587053640309138,0.09500082791205905,-0.8287924672030076,-0.2609563355332265,0.5988184783374502,-0.5587053640309138,0.2857692407025649,1.327766595224347,0.4117022638315761,0.4117022638315761,-0.3925286203228279,0.31734400267200297,-0.29373844618932715,0.34885740302862467,0.19067127264620573,0.6298028841948623,-2.042021033479733,-0.16304347134508207,0.25413257026133235,-0.22824695247054547,-0.2609563355332265,-0.06576592628969985,-0.13054795621506413,-0.2609563355332265,1.387215394486587,0.2857692407025649,-0.16304347134508207,-0.3265940252928932,0.2224334357534765,0.3803099800917596,-0.6257295573052645,1.027635769907882,0.6916031594494587,-0.3595238272390506,0.9973494401983068,-0.6257295573052645,-0.525313577596298,-0.3265940252928932,-0.42560918711049844,0.2857692407025649,-0.0012581004565036626,0.9670119136618348,8.21990109917503,0.9670119136618348,0.030894617027511038,-0.726880811724572,0.44303477605405855,0.9061816816409076,-0.22824695247054547,-0.4587663248239629,-0.5587053640309138,0.5366787829519797,0.030894617027511038,0.25413257026133235	3643
Positive regulation of immune effector process	16	43	2.654071914493613	0.0079526876027438	Q9NUQ9,Q9BY67,Q06481,P02786,Q7Z434,P51809,P30511,P14174,Q01650,O15400,O95219,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0	Processes and pathways	GO Biological process	msigdb_gobp	102,304,39,409,420,476,138,15,143,586,235,590,87,429,522,227	586,2502,2860,2796,235,87,1872,409,2508,590,2509,653,3256,1082,15,1878,138,2229,3297,1548,476,143,39,1727,2526,2532,2535,969,420,2178,2377,1923,914,1928,3235,304,522,638,2394,227,102,429,3098	0.5366787829519797,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,1.1482768495977804,2.11542427763213,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.3265940252928932,0.47430803058067816,-0.8287924672030076,0.2224334357534765,4.964849362308119,-0.098122333905974,1.623176179314646,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,0.6607309570482511,1.5938382520831849,3.257840018273795,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,0.7531817696547146,-0.19560956934146895,-0.2609563355332265,-0.098122333905974,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.9973494401983068,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,1.9718833674139287,0.7531817696547146,-0.6593637349435877	3643
Anion transmembrane transport	22	50	2.6538297626689755	0.0079583966150884	Q86VD7,Q14728,Q01650,Q9HC21,Q9Y619,Q9Y666,Q9UHG3,P21796,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P45880,P51790,P51798,P41440,Q9Y6M7	Processes and pathways	GO Biological process	msigdb_gobp	256,624,143,553,693,694,430,34,152,306,577,44,573,662,54,440,733,78,459,460,90,361	1003,2754,2219,1450,3068,152,1962,1873,3218,1374,704,2331,1145,34,54,2342,90,78,459,3607,460,2073,44,440,2812,143,2771,2672,624,1317,662,3042,256,1177,573,2829,2906,577,733,1057,553,1844,306,430,924,2205,2640,693,694,361	0.25413257026133235,-0.4587663248239629,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.13054795621506413,-0.098122333905974,-0.7947358122572576,0.09500082791205905,0.44303477605405855,-0.2609563355332265,0.19067127264620573,3.528055524230381,2.707887319665007,-0.2609563355332265,2.058127752852981,2.286376867508823,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.16304347134508207,3.1215736355280526,0.7224199472328477,-0.4920008457387619,1.5938382520831849,-0.4587663248239629,-0.3925286203228279,0.5055225334229401,0.12695555655645674,0.47430803058067816,-0.6257295573052645,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.5988184783374502,-0.06576592628969985,0.9973494401983068,0.7531817696547146,0.31734400267200297,-0.19560956934146895,-0.3595238272390506,0.47430803058067816,0.47430803058067816,0.8756881681175116	3643
Inability to walk	14	91	2.64667492150507	0.0081287452703548	Q9NR77,P11166,Q99720,Q96N66,Q7RTS9,P00846,O75787,Q71SY5,Q9H9S5,O75503,Q96RR1,Q96CU9,P07196,Q9GZY8	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,279,2,358,11,74,296,144,347,24,319,92,125,130	1605,2049,2499,746,2212,2216,2136,24,296,2417,1869,791,2653,74,125,1874,3320,279,2331,591,1878,2225,1796,2339,844,1968,2972,753,754,1973,2431,2661,3033,1975,1882,1301,3441,2241,1387,797,3158,1809,2079,2168,1562,2885,3473,2529,899,1317,963,1165,666,1825,2729,144,1409,464,11,2606,1323,2895,544,673,860,812,2012,813,2180,2381,2182,92,3518,358,401,1675,319,2020,3178,2,2549,3181,130,1936,347,32,1197,3243,1946,2207,1068	-0.0012581004565036626,-0.16304347134508207,-0.3265940252928932,0.4117022638315761,-0.22824695247054547,-0.22824695247054547,-0.19560956934146895,4.11230346222967,0.9973494401983068,-0.29373844618932715,-0.098122333905974,0.3803099800917596,-0.3925286203228279,2.371337868662573,1.7400910153055076,-0.098122333905974,-0.8971691305719629,1.027635769907882,-0.2609563355332265,0.5366787829519797,-0.098122333905974,-0.22824695247054547,-0.06576592628969985,-0.2609563355332265,0.34885740302862467,-0.13054795621506413,-0.5921770650124923,0.4117022638315761,0.4117022638315761,-0.13054795621506413,-0.29373844618932715,-0.3925286203228279,-0.6257295573052645,-0.13054795621506413,-0.098122333905974,0.12695555655645674,-1.104482929673742,-0.22824695247054547,0.09500082791205905,0.3803099800917596,-0.726880811724572,-0.06576592628969985,-0.16304347134508207,-0.19560956934146895,0.030894617027511038,-0.525313577596298,-1.174345720866778,-0.3265940252928932,0.31734400267200297,0.12695555655645674,0.2857692407025649,0.19067127264620573,0.47430803058067816,-0.06576592628969985,-0.42560918711049844,1.5938382520831849,0.09500082791205905,0.6916031594494587,5.543953911878619,-0.3595238272390506,0.12695555655645674,-0.525313577596298,0.5988184783374502,0.47430803058067816,0.34885740302862467,0.3803099800917596,-0.13054795621506413,0.3803099800917596,-0.19560956934146895,-0.2609563355332265,-0.19560956934146895,2.0294198239892403,-1.2798752825252815,0.8756881681175116,0.7838890695289682,-0.0012581004565036626,0.9670119136618348,-0.13054795621506413,-0.726880811724572,8.21990109917503,-0.3265940252928932,-0.726880811724572,1.7109272480905777,-0.098122333905974,0.9061816816409076,3.6085359292973544,0.19067127264620573,-0.7947358122572576,-0.098122333905974,-0.19560956934146895,0.25413257026133235	3643
Aplasia hypoplasia involving the vertebral column	6	17	2.636260432607297	0.0083825368035175	P16278,P04066,Q7RTS9,O95831,Q14739,Q96HY6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,228,11,47,416,384	1210,2412,47,228,455,1377,155,707,1973,3297,1893,416,1566,1905,11,974,384	0.15884550726049723,-0.29373844618932715,3.0119856905575273,1.1783129469800828,0.6916031594494587,0.09500082791205905,1.5350292358486646,0.44303477605405855,-0.13054795621506413,-0.8629365633590367,-0.098122333905974,0.7531817696547146,0.030894617027511038,-0.098122333905974,5.543953911878619,0.2857692407025649,0.8145422833591529	3643
Anion transmembrane transporter activity	25	57	2.6323732433504663	0.0084790656030746	Q86VD7,Q14728,Q01650,Q9H813,Q9HC21,Q9Y619,Q9Y666,P11166,P21796,O00400,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P45880,P51790,P51798,P41440,Q9Y6M7,O43681	Functions	GO Molecular function	msigdb_gomf	256,624,143,150,553,693,694,279,34,646,152,306,577,44,573,662,54,440,733,78,459,460,90,361,118	3065,646,2793,1003,118,2754,1450,152,1962,1873,704,1144,279,2331,1145,34,54,2342,90,78,459,3607,460,2073,44,440,143,2771,624,963,662,3042,2274,1657,2366,3456,256,1177,573,2829,2906,2907,1262,2292,577,2841,733,150,1057,553,306,924,2205,693,694,3315,361	-0.6593637349435877,0.47430803058067816,-0.4920008457387619,0.25413257026133235,1.7982903969638317,-0.4587663248239629,0.06298071889501843,1.5350292358486646,-0.13054795621506413,-0.098122333905974,0.44303477605405855,0.19067127264620573,1.027635769907882,-0.2609563355332265,0.19067127264620573,3.528055524230381,2.707887319665007,-0.2609563355332265,2.058127752852981,2.286376867508823,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.16304347134508207,3.1215736355280526,0.7224199472328477,1.5938382520831849,-0.4587663248239629,0.5055225334229401,0.2857692407025649,0.47430803058067816,-0.6257295573052645,-0.22824695247054547,-0.0012581004565036626,-0.2609563355332265,-1.1393655482262741,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.15884550726049723,-0.22824695247054547,0.5677772700633923,-0.4920008457387619,0.44303477605405855,1.5644560394229112,0.25413257026133235,0.5988184783374502,0.9973494401983068,0.31734400267200297,-0.19560956934146895,0.47430803058067816,0.47430803058067816,-0.8629365633590367,0.8756881681175116	3643
Positive regulation of cell activation	17	47	2.6311929557248948	0.0085085712388426	P23396,Q9NUQ9,Q9HCL2,Q15046,P04439,P51809,P02786,P30511,P14174,P12956,O95219,P30825,Q9NPF0,P00813,O96028,Q9NRA0,P31749	Processes and pathways	GO Biological process	msigdb_gobp	437,102,5,566,590,476,409,138,15,83,235,54,492,56,87,227,592	1952,2792,2215,2860,235,87,2757,56,409,2508,590,1081,3256,1082,83,15,3629,437,138,54,592,1547,1548,3440,476,1632,1390,1815,1395,1727,2526,1315,566,3621,1100,2535,969,2015,2619,914,1928,5,492,638,227,102,2788	-0.13054795621506413,-0.4920008457387619,-0.22824695247054547,-0.525313577596298,1.1482768495977804,2.11542427763213,-0.4587663248239629,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,-0.8287924672030076,0.2224334357534765,2.172563346869744,4.964849362308119,-2.997816021189173,0.7224199472328477,1.623176179314646,2.707887319665007,0.5366787829519797,0.030894617027511038,0.030894617027511038,-1.104482929673742,0.6607309570482511,-0.0012581004565036626,0.09500082791205905,-0.06576592628969985,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,0.12695555655645674,0.5677772700633923,-2.4183808791889665,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.13054795621506413,-0.3595238272390506,0.31734400267200297,-0.098122333905974,6.233993929662534,0.6607309570482511,0.5055225334229401,1.2083001127798034,1.9718833674139287,-0.4587663248239629	3643
Cytokine production	25	112	2.619640125342265	0.0088022601708579	Q9HCL2,P30511,P14174,Q01650,P14373,Q9NY93,P05067,P19474,Q06481,Q9BY67,Q7Z434,O75787,O75116,Q9Y6M1,Q13049,P23396,Q8IV08,Q8WXW3,P78536,P41440,Q9NRA0,Q9NUQ9,P17655,Q01082,O75955	Processes and pathways	GO Biological process	msigdb_gobp	5,138,15,143,395,429,29,36,39,304,420,296,293,324,188,437,73,468,216,90,227,102,473,365,249	1527,1209,1210,1001,2502,2574,1216,2794,293,3216,296,249,1698,2757,1872,703,2508,2863,590,29,1012,1789,1457,1081,653,1792,2511,3256,1704,15,395,941,473,1878,36,2225,1015,437,1148,616,2928,138,3615,3407,3520,2229,2764,1296,1547,90,756,709,3156,795,1557,1156,216,3038,2881,365,143,800,1815,39,1310,1394,1395,188,1092,2672,2267,1038,1097,1098,420,73,2609,2828,468,2178,1749,2100,1834,978,1923,2621,1674,863,3176,3177,3053,919,3002,304,3479,522,5,2394,227,989,102,429,828,1358,3098,2308,1689,3556,1204,1951,1443,324	0.030894617027511038,0.15884550726049723,0.15884550726049723,0.25413257026133235,-0.3265940252928932,-0.3595238272390506,0.15884550726049723,-0.4920008457387619,0.9973494401983068,-0.7947358122572576,0.9973494401983068,1.118191455601226,-0.03347806686168351,-0.4587663248239629,-0.098122333905974,0.44303477605405855,-0.3265940252928932,-0.525313577596298,0.5366787829519797,3.6353042018995785,0.25413257026133235,-0.06576592628969985,0.06298071889501843,0.2224334357534765,0.47430803058067816,-0.06576592628969985,-0.3265940252928932,-0.8287924672030076,-0.03347806686168351,4.964849362308119,0.7838890695289682,0.2857692407025649,0.6607309570482511,-0.098122333905974,3.3662912544280115,-0.22824695247054547,0.25413257026133235,0.7224199472328477,0.19067127264620573,0.5055225334229401,-0.5587053640309138,1.623176179314646,-2.2291720974867153,-1.0350054838275398,-1.315246174406957,-0.22824695247054547,-0.4587663248239629,0.12695555655645674,0.030894617027511038,2.058127752852981,0.4117022638315761,0.44303477605405855,-0.726880811724572,0.3803099800917596,0.030894617027511038,0.19067127264620573,1.2382387072449188,-0.6257295573052645,-0.525313577596298,0.845141841466991,1.5938382520831849,0.3803099800917596,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.09500082791205905,0.09500082791205905,1.387215394486587,0.2224334357534765,-0.3925286203228279,-0.22824695247054547,0.25413257026133235,0.2224334357534765,0.2224334357534765,0.7531817696547146,2.399583395405736,-0.3595238272390506,-0.4920008457387619,0.6916031594494587,-0.19560956934146895,-0.03347806686168351,-0.16304347134508207,-0.06576592628969985,0.2857692407025649,-0.098122333905974,-0.3595238272390506,-0.0012581004565036626,0.34885740302862467,-0.726880811724572,-0.726880811724572,-0.6257295573052645,0.31734400267200297,-0.5921770650124923,0.9973494401983068,-1.174345720866778,0.6298028841948623,6.233993929662534,-0.2609563355332265,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.7531817696547146,0.3803099800917596,0.12695555655645674,-0.6593637349435877,-0.22824695247054547,-0.0012581004565036626,-1.4576838354723742,0.19067127264620573,-0.098122333905974,0.09500082791205905,0.9670119136618348	3643
Distal muscle weakness	14	70	2.616394253158995	0.0088863885189505	Q9NR77,Q99720,Q7Z406,Q8TD16,P00846,Q14203,O95831,P02545,Q71SY5,P06753,P39210,P41440,P07196,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,300,272,74,415,47,265,144,394,267,90,125,156	2049,746,2212,3404,2417,791,1782,47,74,265,394,125,2142,1376,3257,1221,1878,2927,944,1971,754,1544,2711,267,2232,2662,90,890,2432,1800,1155,2156,2073,2242,2716,2349,2880,3471,156,2358,1992,415,2087,2529,1165,2363,3502,627,668,1825,2729,2946,144,464,300,3047,3393,272,2830,2622,1675,1053,2,577,32,1274,1767,608,1604,1068	-0.16304347134508207,0.4117022638315761,-0.22824695247054547,-1.0350054838275398,-0.29373844618932715,0.3803099800917596,-0.06576592628969985,3.0119856905575273,2.371337868662573,1.0578712931665288,0.7838890695289682,1.7400910153055076,-0.19560956934146895,0.09500082791205905,-0.8287924672030076,0.15884550726049723,-0.098122333905974,-0.5587053640309138,0.2857692407025649,-0.13054795621506413,0.4117022638315761,0.030894617027511038,-0.42560918711049844,1.0578712931665288,-0.22824695247054547,-0.3925286203228279,2.058127752852981,0.31734400267200297,-0.29373844618932715,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.16304347134508207,-0.22824695247054547,-0.42560918711049844,-0.2609563355332265,-0.525313577596298,-1.174345720866778,1.5350292358486646,-0.2609563355332265,-0.13054795621506413,0.7531817696547146,-0.16304347134508207,-0.3265940252928932,0.19067127264620573,-0.2609563355332265,-1.244601121096576,0.5055225334229401,0.47430803058067816,-0.06576592628969985,-0.42560918711049844,-0.5587053640309138,1.5938382520831849,0.6916031594494587,0.9973494401983068,-0.6257295573052645,-1.0004082879139022,1.0578712931665288,-0.4920008457387619,-0.3595238272390506,-0.0012581004565036626,0.25413257026133235,8.21990109917503,0.5677772700633923,3.6085359292973544,0.15884550726049723,-0.03347806686168351,0.5366787829519797,0.030894617027511038,0.25413257026133235	3643
Cell adhesion	14	41	2.614470150118352	0.0089365968983374	P35579,P07942,P35580,Q08380,P35221,Q9BY67,Q9BQT9,Q96F07,Q92797,P10586,O00192,Q9BX67,P00813,P05067	Processes and pathways	Protein Atlas Biological process	protein_atlas_biological_process	280,126,222,254,534,304,275,344,149,119,389,488,56,29	389,789,1076,1959,56,3149,29,3218,1012,126,119,3257,3468,942,1620,843,534,708,280,222,1633,2162,2259,254,1395,1993,1031,1033,1315,1996,2271,855,149,1049,344,574,275,488,304,1587,1443	0.7838890695289682,0.3803099800917596,0.2224334357534765,-0.13054795621506413,2.6800374279695216,-0.726880811724572,3.6353042018995785,-0.7947358122572576,0.25413257026133235,1.7109272480905777,1.7982903969638317,-0.8287924672030076,-1.174345720866778,0.2857692407025649,-0.0012581004565036626,0.34885740302862467,0.5988184783374502,0.44303477605405855,1.027635769907882,1.2083001127798034,-0.0012581004565036626,-0.19560956934146895,-0.22824695247054547,1.08805639508316,0.09500082791205905,-0.13054795621506413,0.25413257026133235,0.25413257026133235,0.12695555655645674,-0.13054795621506413,-0.22824695247054547,0.34885740302862467,1.5644560394229112,0.25413257026133235,0.9061816816409076,0.5677772700633923,1.0578712931665288,0.6607309570482511,0.9973494401983068,0.030894617027511038,0.09500082791205905	3643
Lipid binding	30	157	2.608249537907955	0.0091006584248858	Q14108,O15118,Q8WTV0,O94788,O14773,Q9UM22,O00291,Q8NCC3,P11717,P21796,Q06481,P28070,A6NIH7,P07602,P50897,O15173,Q96RU3,P45880,Q9Y4G8,O15254,Q9H4L5,Q15075,P61916,Q9Y5X1,Q53T59,Q01082,Q9NS86,O95219,Q9NWW5,Q6ZVM7	Functions	GO Molecular function	msigdb_gomf	255,252,8,9,391,22,390,28,154,34,39,164,46,69,72,199,204,78,81,89,100,354,351,107,366,365,117,235,251,381	1206,46,932,390,1605,834,2322,453,3510,391,1774,2571,252,199,89,3101,2216,2963,1004,529,1213,588,2700,1367,3144,9,2417,2798,235,2507,1787,703,2508,2054,3191,69,1080,3106,1081,3256,2144,3023,2800,154,1378,3591,560,34,1797,1293,2762,164,3196,1381,3615,592,3261,1225,2431,847,78,3035,709,2934,72,3265,3157,1804,1302,3558,2159,2349,3515,2244,351,3120,2163,1392,365,39,3411,507,540,2596,2528,1030,255,2088,3301,1163,2530,964,354,902,366,666,1572,381,2537,1494,1911,2372,1410,2948,28,2900,3477,8,515,1921,3308,1049,1050,980,575,204,1263,3235,3179,1676,2999,3630,2688,2114,1347,984,3212,1424,549,2479,3213,100,2116,2482,117,2695,251,1432,1064,1944,3008,2308,1854,22,3285,1596,1855,2564,3585,3493,1437,2206,81,107,433,2407,1525	0.15884550726049723,3.0942250631129866,0.2857692407025649,0.7838890695289682,-0.0012581004565036626,0.34885740302862467,-0.2609563355332265,0.6916031594494587,-1.2798752825252815,0.7838890695289682,-0.06576592628969985,-0.3595238272390506,1.08805639508316,1.327766595224347,2.0867958206204555,-0.6930805097254553,-0.22824695247054547,-0.5921770650124923,0.25413257026133235,0.5988184783374502,0.15884550726049723,0.5366787829519797,-0.42560918711049844,0.09500082791205905,-0.726880811724572,5.816916168706705,-0.29373844618932715,-0.4920008457387619,1.1482768495977804,-0.3265940252928932,-0.06576592628969985,0.44303477605405855,-0.3265940252928932,-0.16304347134508207,-0.7607655898218467,2.427791890653298,0.2224334357534765,-0.6930805097254553,0.2224334357534765,-0.8287924672030076,-0.19560956934146895,-0.6257295573052645,-0.4920008457387619,1.5350292358486646,0.09500082791205905,-1.7470088834303552,0.5677772700633923,3.528055524230381,-0.06576592628969985,0.12695555655645674,-0.4587663248239629,1.5055575321040489,-0.7607655898218467,0.09500082791205905,-2.2291720974867153,0.5366787829519797,-0.8287924672030076,0.15884550726049723,-0.29373844618932715,0.34885740302862467,2.286376867508823,-0.6257295573052645,0.44303477605405855,-0.5587053640309138,2.399583395405736,-0.8287924672030076,-0.726880811724572,-0.06576592628969985,0.12695555655645674,-1.4935285643358234,-0.19560956934146895,-0.2609563355332265,-1.2798752825252815,-0.22824695247054547,0.8756881681175116,-0.6930805097254553,-0.19560956934146895,0.09500082791205905,0.845141841466991,3.257840018273795,-1.0350054838275398,0.6298028841948623,0.5988184783374502,-0.3595238272390506,-0.3265940252928932,0.25413257026133235,1.08805639508316,-0.16304347134508207,-0.8629365633590367,0.19067127264620573,-0.3265940252928932,0.2857692407025649,0.8756881681175116,0.31734400267200297,0.845141841466991,0.47430803058067816,0.030894617027511038,0.8145422833591529,-0.3265940252928932,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.09500082791205905,-0.5587053640309138,3.768713037747525,-0.525313577596298,-1.174345720866778,5.940175937290734,0.6298028841948623,-0.098122333905974,-0.8629365633590367,0.25413257026133235,0.25413257026133235,0.2857692407025649,0.5677772700633923,1.327766595224347,0.15884550726049723,-0.7947358122572576,-0.726880811724572,-0.0012581004565036626,-0.5921770650124923,-3.1552041982193537,-0.3925286203228279,-0.16304347134508207,0.12695555655645674,0.2857692407025649,-0.7607655898218467,0.09500082791205905,0.5988184783374502,-0.29373844618932715,-0.7607655898218467,1.9718833674139287,-0.16304347134508207,-0.29373844618932715,1.8273265764439528,-0.3925286203228279,1.118191455601226,0.09500082791205905,0.25413257026133235,-0.098122333905974,-0.5921770650124923,-0.22824695247054547,-0.06576592628969985,4.373525061543824,-0.8287924672030076,0.030894617027511038,-0.06576592628969985,-0.3265940252928932,-1.6741333670170677,-1.209424370050621,0.09500082791205905,-0.19560956934146895,2.2579809707838456,1.943054324684516,0.7531817696547146,-0.2609563355332265,0.06298071889501843	3643
Dysphagia	39	144	2.5977718077875656	0.0093830826056704	Q05639,Q99720,Q01105,Q14108,O15344,O15118,Q9HD42,Q8IZA0,Q8N3U4,P06753,P05067,Q9NR77,O60313,Q9UHX1,Q8N0X7,P15586,Q14203,Q14739,Q96RR1,P29372,P03886,P20700,P55011,O95155,P07602,Q15233,P00846,Q7LG56,Q9Y4W6,P48735,P17480,P61916,O75569,O75306,Q14331,P42356,Q8NFF5,Q9UEY8,Q9GZY8	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	622,2,505,255,253,252,276,141,673,394,29,32,529,171,421,410,415,416,319,438,62,310,440,307,69,567,74,464,608,339,591,351,350,471,477,617,382,526,130	1605,1862,1210,2049,252,253,2504,529,1078,2136,471,3145,350,1284,881,2417,1869,307,2649,1782,3103,3147,74,1872,62,2967,703,2654,29,394,69,1080,1874,2142,1375,2058,3257,2512,2331,410,591,1707,1221,310,1796,1148,2339,2971,438,3260,753,754,2431,617,1882,890,339,1301,2073,2242,1088,1387,440,2349,797,1471,3158,3471,351,2252,1025,2590,1026,952,505,2721,622,2358,1309,955,3270,1992,3473,255,415,2087,477,899,416,964,1165,567,1096,2820,2454,1827,464,3047,1044,141,421,3088,673,2898,382,813,3091,2612,3518,2835,980,2624,1675,319,2736,3176,3178,2,3054,2549,2387,1054,3416,130,3418,1056,276,32,826,1850,1064,689,1852,1521,2913,526,1522,171,2562,928,1203,2312,1765,608	-0.0012581004565036626,-0.098122333905974,0.15884550726049723,-0.16304347134508207,1.08805639508316,1.08805639508316,-0.3265940252928932,0.5988184783374502,0.2224334357534765,-0.19560956934146895,0.6607309570482511,-0.726880811724572,0.8756881681175116,0.12695555655645674,0.31734400267200297,-0.29373844618932715,-0.098122333905974,0.9670119136618348,-0.3925286203228279,-0.06576592628969985,-0.6930805097254553,-0.726880811724572,2.371337868662573,-0.098122333905974,2.512197372488192,-0.5921770650124923,0.44303477605405855,-0.3925286203228279,3.6353042018995785,0.7838890695289682,2.427791890653298,0.2224334357534765,-0.098122333905974,-0.19560956934146895,0.09500082791205905,-0.16304347134508207,-0.8287924672030076,-0.3265940252928932,-0.2609563355332265,0.7531817696547146,0.5366787829519797,-0.03347806686168351,0.15884550726049723,0.9670119136618348,-0.06576592628969985,0.19067127264620573,-0.2609563355332265,-0.5921770650124923,0.7224199472328477,-0.8287924672030076,0.4117022638315761,0.4117022638315761,-0.29373844618932715,0.5055225334229401,-0.098122333905974,0.31734400267200297,0.9061816816409076,0.12695555655645674,-0.16304347134508207,-0.22824695247054547,0.2224334357534765,0.09500082791205905,0.7224199472328477,-0.2609563355332265,0.3803099800917596,0.06298071889501843,-0.726880811724572,-1.174345720866778,0.8756881681175116,-0.22824695247054547,0.25413257026133235,-0.3595238272390506,0.25413257026133235,0.2857692407025649,0.6298028841948623,-0.42560918711049844,0.5055225334229401,-0.2609563355332265,0.12695555655645674,0.2857692407025649,-0.8287924672030076,-0.13054795621506413,-1.174345720866778,1.08805639508316,0.7531817696547146,-0.16304347134508207,0.6607309570482511,0.31734400267200297,0.7531817696547146,0.2857692407025649,0.19067127264620573,0.5677772700633923,0.2224334357534765,-0.4920008457387619,-0.29373844618932715,-0.06576592628969985,0.6916031594494587,-0.6257295573052645,0.25413257026133235,1.623176179314646,0.7531817696547146,-0.6593637349435877,0.47430803058067816,-0.525313577596298,0.8145422833591529,0.3803099800917596,-0.6593637349435877,-0.3595238272390506,-1.2798752825252815,-0.4920008457387619,0.2857692407025649,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,-0.42560918711049844,-0.726880811724572,-0.726880811724572,8.21990109917503,-0.6257295573052645,-0.3265940252928932,-0.2609563355332265,0.25413257026133235,-1.0350054838275398,1.7109272480905777,-1.0350054838275398,0.25413257026133235,1.0578712931665288,3.6085359292973544,0.3803099800917596,-0.06576592628969985,0.25413257026133235,0.47430803058067816,-0.06576592628969985,0.06298071889501843,-0.525313577596298,0.6298028841948623,0.06298071889501843,1.5055575321040489,-0.3265940252928932,0.31734400267200297,0.19067127264620573,-0.22824695247054547,-0.03347806686168351,0.5366787829519797	3643
Signaling receptor regulator activity	8	23	2.574594925710308	0.0100357543748448	P49354,P22466,P43490,P14174,Q15375,P30533,Q9UMX5,P05067	Functions	GO Molecular function	msigdb_gomf	229,38,71,15,418,457,27,29	29,2509,1081,15,1084,38,616,457,71,229,2584,2521,3515,2433,3079,2082,2269,418,1044,677,492,27,2405	3.6353042018995785,-0.3265940252928932,0.2224334357534765,4.964849362308119,0.2224334357534765,3.257840018273795,0.5055225334229401,0.6916031594494587,2.399583395405736,1.1783129469800828,-0.3595238272390506,-0.3265940252928932,-1.2798752825252815,-0.29373844618932715,-0.6593637349435877,-0.16304347134508207,-0.22824695247054547,0.7531817696547146,0.25413257026133235,0.47430803058067816,0.6607309570482511,3.795309279757627,-0.2609563355332265	3643
Exopeptidase activity	11	34	2.572909071734808	0.0100847699036699	Q9H3G5,Q9HB40,P42785,Q9UIQ6,Q9NZ08,O75976,O14773,Q9NQH7,O75844,P10619,P55786	Functions	GO Molecular function	msigdb_gomf	359,35,4,42,245,206,391,386,248,59,31	391,248,206,409,2222,59,3108,3323,2659,1544,4,3298,1554,1632,31,2883,3347,2773,2776,1322,2005,1417,913,3395,1188,3179,359,3554,35,386,3241,3137,245,42	0.7838890695289682,1.118191455601226,1.2979715997804608,0.7531817696547146,-0.22824695247054547,2.5402599154147643,-0.6930805097254553,-0.8971691305719629,-0.3925286203228279,0.030894617027511038,6.233993929662534,-0.8629365633590367,0.030894617027511038,-0.0012581004565036626,3.6085359292973544,-0.525313577596298,-0.931491220478586,-0.4587663248239629,-0.4587663248239629,0.12695555655645674,-0.13054795621506413,0.09500082791205905,0.31734400267200297,-1.0004082879139022,0.19067127264620573,-0.726880811724572,0.8756881681175116,-1.4576838354723742,3.447308651903207,0.8145422833591529,-0.7947358122572576,-0.6930805097254553,1.1482768495977804,3.2306497156014906	3643
Azurophil granule membrane	7	25	2.5723453441188138	0.0101012075552375	P42785,P07602,O15260,Q07065,P15291,P10253,Q9NQX7	Localization	GO Cellular component	msigdb_gocc	4,69,108,173,112,266,122	108,2700,1078,1456,69,266,3219,1082,2332,112,563,3200,4,1300,476,173,2001,1916,317,3179,2115,122,2912,1064,1199	1.914184390727662,-0.42560918711049844,0.2224334357534765,0.06298071889501843,2.427791890653298,1.0578712931665288,-0.7947358122572576,0.2224334357534765,-0.2609563355332265,1.8563207862044178,0.5677772700633923,-0.7607655898218467,6.233993929662534,0.12695555655645674,0.6607309570482511,1.4760406150941263,-0.13054795621506413,-0.098122333905974,0.9670119136618348,-0.726880811724572,-0.16304347134508207,1.7692119702003737,-0.525313577596298,0.25413257026133235,0.19067127264620573	3643
Nucleophile aminohydrolases, N-terminal [IPR029055]	6	17	2.5569091630022527	0.0105606790936645	P28070,P28074,P20618,P28072,Q99436,P49721	Sequence	InterPro Superfamily	interpro_homologous_superfamily	164,41,137,146,121,60	3142,1875,137,2762,1461,1621,2802,3222,164,146,41,2878,60,283,2525,2358,121	-0.726880811724572,-0.098122333905974,1.623176179314646,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.525313577596298,2.5402599154147643,1.027635769907882,-0.3265940252928932,-0.2609563355332265,1.7692119702003737	3643
Supranuclear gaze palsy	7	20	2.5433185168738404	0.0109805082050193	Q99720,P07602,O15118,P61916,Q14203,Q96RR1,Q969N2	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,69,252,351,415,319,318	1862,1210,252,703,69,2655,3260,754,2242,2349,351,1992,415,318,1675,319,2,1064,2913,526	-0.098122333905974,0.15884550726049723,1.08805639508316,0.44303477605405855,2.427791890653298,-0.3925286203228279,-0.8287924672030076,0.4117022638315761,-0.22824695247054547,-0.2609563355332265,0.8756881681175116,-0.13054795621506413,0.7531817696547146,0.9670119136618348,-0.0012581004565036626,0.9670119136618348,8.21990109917503,0.25413257026133235,-0.525313577596298,0.6298028841948623	3643
Neuron death	17	76	2.538717014929464	0.0111259776198344	Q99720,Q01105,P50897,P17655,P30511,Q15392,Q13464,O95831,Q96A26,Q15375,Q92542,P31751,P07196,Q99538,Q969N2,Q9UMX5,P05067	Processes and pathways	GO Biological process	msigdb_gobp	2,505,72,473,138,45,328,47,243,418,317,364,125,520,318,27,29	1606,3495,2861,3068,881,885,47,703,3291,2863,1288,29,1010,2509,125,1457,2866,653,1791,1704,840,473,138,592,364,3520,708,1548,3155,2582,757,2236,1800,1801,72,1301,2584,1723,2806,3163,2251,2769,3079,505,2721,506,2168,328,2596,1401,1240,567,418,45,1902,2455,317,318,243,3332,1923,2624,3177,520,2,1056,2391,2631,779,2038,3569,1274,1594,27,1855,1768	-0.0012581004565036626,-1.244601121096576,-0.525313577596298,-0.6593637349435877,0.31734400267200297,0.31734400267200297,3.0119856905575273,0.44303477605405855,-0.8629365633590367,-0.525313577596298,0.12695555655645674,3.6353042018995785,0.25413257026133235,-0.3265940252928932,1.7400910153055076,0.06298071889501843,-0.525313577596298,0.47430803058067816,-0.06576592628969985,-0.03347806686168351,0.34885740302862467,0.6607309570482511,1.623176179314646,0.5366787829519797,0.845141841466991,-1.315246174406957,0.44303477605405855,0.030894617027511038,-0.726880811724572,-0.3595238272390506,0.4117022638315761,-0.22824695247054547,-0.06576592628969985,-0.06576592628969985,2.399583395405736,0.12695555655645674,-0.3595238272390506,-0.03347806686168351,-0.4920008457387619,-0.726880811724572,-0.22824695247054547,-0.4587663248239629,-0.6593637349435877,0.6298028841948623,-0.42560918711049844,0.6298028841948623,-0.19560956934146895,0.9366227945511973,-0.3595238272390506,0.09500082791205905,0.15884550726049723,0.5677772700633923,0.7531817696547146,3.1215736355280526,-0.098122333905974,-0.29373844618932715,0.9670119136618348,0.9670119136618348,1.1482768495977804,-0.8971691305719629,-0.098122333905974,-0.3595238272390506,-0.726880811724572,0.6298028841948623,8.21990109917503,0.25413257026133235,-0.2609563355332265,-0.3595238272390506,0.4117022638315761,-0.13054795621506413,-1.5294661704120023,0.15884550726049723,0.030894617027511038,3.795309279757627,-0.06576592628969985,-0.03347806686168351	3643
Abnormal femoral neck morphology	16	43	2.5355306373984643	0.0112277106746583	P16278,O00754,P55011,P04066,Q8WVQ1,Q96L58,Q9Y487,Q7RTS9,O75718,O95831,P02545,O75431,O75530,O75844,P11274,Q96HY6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,435,440,228,423,303,43,11,295,47,265,213,86,248,338,384	834,435,2412,213,86,295,248,47,265,228,338,155,2337,2147,3197,707,2933,3117,2713,1802,3626,440,2434,900,806,1038,2364,11,423,2612,1048,1112,384,303,2185,3052,3096,524,2041,3012,43,1069,693	0.34885740302862467,0.7224199472328477,-0.29373844618932715,1.2382387072449188,2.11542427763213,0.9973494401983068,1.118191455601226,3.0119856905575273,1.0578712931665288,1.1783129469800828,0.9061816816409076,1.5350292358486646,-0.2609563355332265,-0.19560956934146895,-0.7607655898218467,0.44303477605405855,-0.5587053640309138,-0.6930805097254553,-0.42560918711049844,-0.06576592628969985,-2.919565762049335,0.7224199472328477,-0.29373844618932715,0.31734400267200297,0.3803099800917596,0.25413257026133235,-0.2609563355332265,5.543953911878619,0.7531817696547146,-0.3595238272390506,0.25413257026133235,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.19560956934146895,-0.6257295573052645,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,-0.5921770650124923,3.2306497156014906,0.25413257026133235,0.47430803058067816	3643
Response to oxygen levels	17	71	2.534996792303564	0.0112448355717058	P11166,Q9Y487,P02786,P00846,P80404,P17655,P30519,O95831,P02545,O75116,O43707,Q96A26,P00813,O75592,P78536,Q14457,P55786	Processes and pathways	GO Biological process	msigdb_gobp	279,43,409,74,413,473,14,47,265,293,325,243,56,186,216,189,31	2916,3186,325,293,471,186,2966,3103,47,3148,56,74,265,409,2967,3291,1288,3149,3190,3150,653,279,2513,942,473,1221,1222,2148,14,2972,592,1973,2661,1086,2069,2236,1301,1721,31,2587,216,413,1989,2671,1240,189,661,2091,965,1903,1907,3275,1914,1330,1331,1749,243,1923,2833,3235,2292,3561,2631,1059,3481,784,2043,2562,43,1768,1603	-0.5587053640309138,-0.7607655898218467,0.9366227945511973,0.9973494401983068,0.6607309570482511,1.387215394486587,-0.5921770650124923,-0.6930805097254553,3.0119856905575273,-0.726880811724572,2.6800374279695216,2.371337868662573,1.0578712931665288,0.7531817696547146,-0.5921770650124923,-0.8629365633590367,0.12695555655645674,-0.726880811724572,-0.7607655898218467,-0.726880811724572,0.47430803058067816,1.027635769907882,-0.3265940252928932,0.2857692407025649,0.6607309570482511,0.15884550726049723,0.15884550726049723,-0.19560956934146895,5.1928477731586264,-0.5921770650124923,0.5366787829519797,-0.13054795621506413,-0.3925286203228279,0.2224334357534765,-0.16304347134508207,-0.22824695247054547,0.12695555655645674,-0.03347806686168351,3.6085359292973544,-0.3595238272390506,1.2382387072449188,0.7531817696547146,-0.13054795621506413,-0.3925286203228279,0.15884550726049723,1.387215394486587,0.47430803058067816,-0.16304347134508207,0.2857692407025649,-0.098122333905974,-0.098122333905974,-0.8287924672030076,-0.098122333905974,0.12695555655645674,0.12695555655645674,-0.03347806686168351,1.1482768495977804,-0.098122333905974,-0.4920008457387619,-0.7947358122572576,-0.22824695247054547,-1.4935285643358234,-0.3595238272390506,0.25413257026133235,-1.174345720866778,0.4117022638315761,-0.13054795621506413,-0.3265940252928932,3.2306497156014906,-0.03347806686168351,0.030894617027511038	3643
Endocytic vesicle membrane	13	50	2.533420913463988	0.0112955226160549	P11717,Q14108,P20645,Q06481,Q8WTV0,Q9Y487,P02786,Q13555,P30511,O43493,Q5KU26,Q93050,Q9BZG1	Localization	GO Cellular component	msigdb_gocc	154,255,37,39,8,43,409,105,138,142,396,82,448	1695,142,1449,2798,2328,3617,1872,409,590,532,1082,154,3591,2332,2578,37,2658,138,1155,2156,1552,476,2348,2805,1890,2587,2251,952,2257,1028,39,1727,105,3348,255,1036,902,1166,3124,396,767,970,8,82,1050,3234,448,3479,2041,43	-0.03347806686168351,1.5938382520831849,0.06298071889501843,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,-0.098122333905974,0.7531817696547146,0.5366787829519797,0.5988184783374502,0.2224334357534765,1.5350292358486646,-1.7470088834303552,-0.2609563355332265,-0.3595238272390506,3.284999162596966,-0.3925286203228279,1.623176179314646,0.19067127264620573,-0.19560956934146895,0.030894617027511038,0.6607309570482511,-0.2609563355332265,-0.4920008457387619,-0.098122333905974,-0.3595238272390506,-0.22824695247054547,0.2857692407025649,-0.22824695247054547,0.25413257026133235,3.257840018273795,-0.03347806686168351,1.943054324684516,-0.931491220478586,1.08805639508316,0.25413257026133235,0.31734400267200297,0.19067127264620573,-0.6930805097254553,0.7838890695289682,0.4117022638315761,0.2857692407025649,5.940175937290734,2.2010744460285183,0.25413257026133235,-0.7947358122572576,0.7224199472328477,-1.174345720866778,-0.13054795621506413,3.2306497156014906	3643
Impaired proprioception	17	48	2.5251039871555307	0.0115664058786728	Q9NR77,Q5THJ4,P20700,P41440,Q8IV08,Q8N0X7,P00846,Q9Y448,O75298,Q9H6K4,O14773,P54802,Q5TAQ9,Q96RR1,Q9Y619,P07196,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,668,310,90,73,421,74,348,393,579,391,147,627,319,693,125,156	1770,646,391,1210,2571,2504,393,2417,791,74,2509,125,3256,1221,1878,310,1971,2662,90,2242,147,1387,2349,156,1989,955,801,1238,3328,2091,627,668,2729,2946,73,421,2012,1675,319,2112,1423,579,32,3519,2562,348,693,876	-0.06576592628969985,0.47430803058067816,0.7838890695289682,0.15884550726049723,-0.3595238272390506,-0.3265940252928932,0.7838890695289682,-0.29373844618932715,0.3803099800917596,2.371337868662573,-0.3265940252928932,1.7400910153055076,-0.8287924672030076,0.15884550726049723,-0.098122333905974,0.9670119136618348,-0.13054795621506413,-0.3925286203228279,2.058127752852981,-0.22824695247054547,1.5644560394229112,0.09500082791205905,-0.2609563355332265,1.5350292358486646,-0.13054795621506413,0.2857692407025649,0.3803099800917596,0.15884550726049723,-0.8971691305719629,-0.16304347134508207,0.5055225334229401,0.47430803058067816,-0.42560918711049844,-0.5587053640309138,2.399583395405736,0.7531817696547146,-0.13054795621506413,-0.0012581004565036626,0.9670119136618348,-0.16304347134508207,0.09500082791205905,0.5677772700633923,3.6085359292973544,-1.2798752825252815,-0.3265940252928932,0.9061816816409076,0.47430803058067816,0.34885740302862467	3643
Immune effector process	25	84	2.522648269774979	0.0116474836513349	Q92538,P30511,P14174,Q01650,Q9NY93,P05067,Q9UQ84,Q06481,Q9BY67,P02786,Q7Z434,P00813,P33176,Q15046,P04439,O96028,O15400,P78536,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1	Processes and pathways	GO Biological process	msigdb_gobp	515,138,15,143,429,29,33,39,304,409,420,56,312,566,590,87,586,216,338,227,102,476,638,235,522	1207,586,2502,2860,1217,2646,2796,235,87,3147,56,1872,409,2508,590,1288,29,2509,1701,1081,653,3256,1704,338,1082,3591,3513,15,1084,1878,138,2874,3520,312,2229,1385,3297,1296,1086,1548,2712,476,1553,1632,1233,2161,216,143,1893,2938,39,1310,1395,1727,2526,566,1165,2532,1404,2535,969,1737,420,2993,2178,515,2377,1923,681,914,1928,3235,304,3479,522,638,2394,227,102,3337,429,3098,1855,33	0.15884550726049723,0.5366787829519797,-0.3265940252928932,-0.525313577596298,0.15884550726049723,-0.3925286203228279,-0.4920008457387619,1.1482768495977804,2.11542427763213,-0.726880811724572,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.12695555655645674,3.6353042018995785,-0.3265940252928932,-0.03347806686168351,0.2224334357534765,0.47430803058067816,-0.8287924672030076,-0.03347806686168351,0.9061816816409076,0.2224334357534765,-1.7470088834303552,-1.2798752825252815,4.964849362308119,0.2224334357534765,-0.098122333905974,1.623176179314646,-0.525313577596298,-1.315246174406957,0.9670119136618348,-0.22824695247054547,0.09500082791205905,-0.8629365633590367,0.12695555655645674,0.2224334357534765,0.030894617027511038,-0.42560918711049844,0.6607309570482511,0.030894617027511038,-0.0012581004565036626,0.15884550726049723,-0.19560956934146895,1.2382387072449188,1.5938382520831849,-0.098122333905974,-0.5587053640309138,3.257840018273795,0.12695555655645674,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,0.5677772700633923,0.19067127264620573,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,-0.5921770650124923,-0.19560956934146895,0.6298028841948623,-0.2609563355332265,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.9973494401983068,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,1.9718833674139287,-0.8971691305719629,0.7531817696547146,-0.6593637349435877,-0.06576592628969985,3.6085359292973544	3643
Clumsiness	7	18	2.515118119845394	0.0118992509472619	Q9NR77,P07602,P06753,O14773,O43681,O75503,Q96RR1	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,69,394,391,118,24,319	1770,435,391,1210,118,2504,24,394,69,753,3473,964,2452,2729,319,32,1064,2913	-0.06576592628969985,0.7224199472328477,0.7838890695289682,0.15884550726049723,1.7982903969638317,-0.3265940252928932,4.11230346222967,0.7838890695289682,2.427791890653298,0.4117022638315761,-1.174345720866778,0.2857692407025649,-0.29373844618932715,-0.42560918711049844,0.9670119136618348,3.6085359292973544,0.25413257026133235,-0.525313577596298	3643
Regulation of blood pressure	6	22	2.5109763076607043	0.0120397777158254	Q9HB40,P42785,Q9UIQ6,Q9NZ08,P42892,P09493	Processes and pathways	GO Biological process	msigdb_gobp	35,4,42,245,53,215	296,3291,2054,215,653,1378,1015,2580,4,53,2519,1301,413,1095,2776,2612,519,3533,35,245,42,2407	0.9973494401983068,-0.8629365633590367,-0.16304347134508207,1.2382387072449188,0.47430803058067816,0.09500082791205905,0.25413257026133235,-0.3595238272390506,6.233993929662534,2.763483088965262,-0.3265940252928932,0.12695555655645674,0.7531817696547146,0.2224334357534765,-0.4587663248239629,-0.3595238272390506,0.6298028841948623,-1.3507131280591325,3.447308651903207,1.1482768495977804,3.2306497156014906,-0.2609563355332265	3643
Endoplasmic reticulum lumen	16	69	2.509169332378961	0.0121015457632569	Q02818,P07942,Q14257,Q06481,O00584,Q86UP2,Q8NBJ4,Q9NZ08,Q07065,O43493,Q9BTY2,O43681,Q9NWW5,P78536,Q8IXB1,P05067	Localization	GO Cellular component	msigdb_gocc	65,126,299,39,103,301,75,245,173,142,115,118,251,216,218,29	103,3610,2642,1956,142,118,2698,1958,295,881,1700,29,3150,126,3220,1704,3257,2656,1219,1706,2513,843,2516,3322,2658,1711,3197,2066,3030,457,1886,1632,3515,216,65,39,173,1238,1093,299,2941,1997,2448,3583,2728,1246,2776,2730,301,218,75,2826,3548,1663,1503,2950,1112,2833,2293,1581,115,3001,737,251,1942,245,3283,1768,372	1.943054324684516,-2.1540615170130093,-0.3925286203228279,-0.13054795621506413,1.5938382520831849,1.7982903969638317,-0.42560918711049844,-0.13054795621506413,0.9973494401983068,0.31734400267200297,-0.03347806686168351,3.6353042018995785,-0.726880811724572,1.7109272480905777,-0.7947358122572576,-0.03347806686168351,-0.8287924672030076,-0.3925286203228279,0.15884550726049723,-0.03347806686168351,-0.3265940252928932,0.34885740302862467,-0.3265940252928932,-0.8971691305719629,-0.3925286203228279,-0.03347806686168351,-0.7607655898218467,-0.16304347134508207,-0.6257295573052645,0.6916031594494587,-0.098122333905974,-0.0012581004565036626,-1.2798752825252815,1.2382387072449188,2.4840986629825825,3.257840018273795,1.4760406150941263,0.15884550726049723,0.2224334357534765,0.9973494401983068,-0.5587053640309138,-0.13054795621506413,-0.29373844618932715,-1.6741333670170677,-0.42560918711049844,0.15884550726049723,-0.4587663248239629,-0.42560918711049844,0.9973494401983068,1.2382387072449188,2.371337868662573,-0.4920008457387619,-1.421932600442622,-0.0012581004565036626,0.06298071889501843,-0.5587053640309138,0.2224334357534765,-0.4920008457387619,-0.22824695247054547,0.030894617027511038,1.8563207862044178,-0.5921770650124923,0.44303477605405855,1.118191455601226,-0.098122333905974,1.1482768495977804,-0.8287924672030076,-0.03347806686168351,0.845141841466991	3643
Vesicle lumen	29	131	2.5088092385598992	0.0121138883999325	Q08380,P78371,P20618,P14174,Q8N2G8,P06280,P05067,P16278,O00231,Q8WVQ1,P15586,P00813,Q13813,P10619,O00754,P12814,O15078,Q8NBX0,Q13464,O43707,P12956,Q7L576,Q9NUQ9,P04066,O00584,P61916,Q9BTY2,O43681,Q99436	Localization	GO Cellular component	msigdb_gocc	254,378,137,15,398,153,29,155,278,423,410,56,315,59,435,308,194,331,328,325,83,340,102,228,103,351,115,118,121	278,3316,1135,2322,1209,103,435,611,194,1609,118,325,1284,3103,2704,2757,56,228,2922,2758,29,153,1011,2509,3191,1701,3538,2510,1789,455,1457,3528,1081,3435,59,1704,2144,1964,3193,308,83,1146,1876,15,2868,3468,410,155,1965,2869,2577,1620,2426,137,3294,2063,1461,3222,3197,3324,3407,2709,707,1623,3425,2710,2432,2935,2237,1229,1805,1632,1806,2349,1023,351,1025,2161,2255,378,2813,2938,254,2167,2442,2985,1238,328,315,1239,2087,2268,1485,1097,1173,340,1106,1741,398,2899,676,1663,331,423,677,1417,1835,3092,980,1675,121,1507,2111,683,2293,115,2837,3211,2693,3240,2306,102,2202,3063,2203,2563,2637,2492,2567,609,877	1.027635769907882,-0.8971691305719629,0.19067127264620573,-0.2609563355332265,0.15884550726049723,1.943054324684516,0.7224199472328477,0.5055225334229401,1.3575144142492008,-0.0012581004565036626,1.7982903969638317,0.9366227945511973,0.12695555655645674,-0.6930805097254553,-0.42560918711049844,-0.4587663248239629,2.6800374279695216,1.1783129469800828,-0.5587053640309138,-0.4587663248239629,3.6353042018995785,1.5350292358486646,0.25413257026133235,-0.3265940252928932,-0.7607655898218467,-0.03347806686168351,-1.3862754857551036,-0.3265940252928932,-0.06576592628969985,0.6916031594494587,0.06298071889501843,-1.3507131280591325,0.2224334357534765,-1.104482929673742,2.5402599154147643,-0.03347806686168351,-0.19560956934146895,-0.13054795621506413,-0.7607655898218467,0.9670119136618348,2.172563346869744,0.19067127264620573,-0.098122333905974,4.964849362308119,-0.525313577596298,-1.174345720866778,0.7531817696547146,1.5350292358486646,-0.13054795621506413,-0.525313577596298,-0.3595238272390506,-0.0012581004565036626,-0.29373844618932715,1.623176179314646,-0.8629365633590367,-0.16304347134508207,0.06298071889501843,-0.7947358122572576,-0.7607655898218467,-0.8971691305719629,-1.0350054838275398,-0.42560918711049844,0.44303477605405855,-0.0012581004565036626,-1.069696640684267,-0.42560918711049844,-0.29373844618932715,-0.5587053640309138,-0.22824695247054547,0.15884550726049723,-0.06576592628969985,-0.0012581004565036626,-0.06576592628969985,-0.2609563355332265,0.25413257026133235,0.8756881681175116,0.25413257026133235,-0.19560956934146895,-0.22824695247054547,0.8145422833591529,-0.4920008457387619,-0.5587053640309138,1.08805639508316,-0.19560956934146895,-0.29373844618932715,-0.5921770650124923,0.15884550726049723,0.9366227945511973,0.9670119136618348,0.15884550726049723,-0.16304347134508207,-0.22824695247054547,0.06298071889501843,0.2224334357534765,0.19067127264620573,0.9061816816409076,0.2224334357534765,-0.03347806686168351,0.7838890695289682,-0.525313577596298,0.47430803058067816,-0.0012581004565036626,0.9366227945511973,0.7531817696547146,0.47430803058067816,0.09500082791205905,-0.06576592628969985,-0.6593637349435877,0.2857692407025649,-0.0012581004565036626,1.7692119702003737,0.06298071889501843,-0.16304347134508207,0.47430803058067816,-0.22824695247054547,1.8563207862044178,-0.4920008457387619,-0.7607655898218467,-0.3925286203228279,-0.7947358122572576,-0.22824695247054547,1.9718833674139287,-0.19560956934146895,-0.6257295573052645,-0.19560956934146895,-0.3265940252928932,-0.3595238272390506,-0.29373844618932715,-0.3265940252928932,0.5366787829519797,0.34885740302862467	3643
Abnormal peripheral myelination	10	35	2.507014162559021	0.0121755833110084	Q9NR77,P20700,P03886,P07602,P00846,P02545,Q01082,P39210,O43681,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,310,62,69,74,265,365,267,118,125	746,118,1776,791,1454,74,265,62,2967,125,69,591,1878,310,2228,267,1882,1155,2156,2242,3471,365,2363,627,464,813,3091,1675,1423,3533,32,1357,1064,1272,1279	0.4117022638315761,1.7982903969638317,-0.06576592628969985,0.3803099800917596,0.06298071889501843,2.371337868662573,1.0578712931665288,2.512197372488192,-0.5921770650124923,1.7400910153055076,2.427791890653298,0.5366787829519797,-0.098122333905974,0.9670119136618348,-0.22824695247054547,1.0578712931665288,-0.098122333905974,0.19067127264620573,-0.19560956934146895,-0.22824695247054547,-1.174345720866778,0.845141841466991,-0.2609563355332265,0.5055225334229401,0.6916031594494587,0.3803099800917596,-0.6593637349435877,-0.0012581004565036626,0.09500082791205905,-1.3507131280591325,3.6085359292973544,0.12695555655645674,0.25413257026133235,0.15884550726049723,0.15884550726049723	3643
Immunoglobulin-like fold [IPR013783]	12	37	2.499341134072897	0.0124424472830153	P10321,O15344,Q9BY67,Q8IZA0,P30511,Q8NAT1,Q15375,P08236,P10586,Q9BX67,O75592,Q92545	Sequence	InterPro Superfamily	interpro_homologous_superfamily	532,253,304,141,138,480,418,455,119,488,186,226	1072,253,1695,1005,2412,186,1782,1872,590,455,532,119,2337,138,889,2520,2162,2257,1395,1993,1031,2529,418,1909,2730,141,480,973,1184,226,727,488,304,1199,1362,1951,1443	0.2224334357534765,1.08805639508316,-0.03347806686168351,0.25413257026133235,-0.29373844618932715,1.387215394486587,-0.06576592628969985,-0.098122333905974,0.5366787829519797,0.6916031594494587,0.5988184783374502,1.7982903969638317,-0.2609563355332265,1.623176179314646,0.31734400267200297,-0.3265940252928932,-0.19560956934146895,-0.22824695247054547,0.09500082791205905,-0.13054795621506413,0.25413257026133235,-0.3265940252928932,0.7531817696547146,-0.098122333905974,-0.42560918711049844,1.623176179314646,0.6607309570482511,0.2857692407025649,0.19067127264620573,1.2083001127798034,0.44303477605405855,0.6607309570482511,0.9973494401983068,0.19067127264620573,0.12695555655645674,-0.098122333905974,0.09500082791205905	3643
Plasma membrane organization	11	37	2.4993046597267807	0.0124437281156259	P35579,P41440,Q9HD42,Q16739,P16615,Q9Y5X1,Q01082,Q8N3R9,O75955,Q9UQB8,Q96CP7	Processes and pathways	GO Biological process	msigdb_gobp	280,90,276,330,172,107,365,148,249,26,64	2793,2963,249,3106,1704,172,592,364,280,90,1628,1155,365,2938,1727,1398,1165,330,3042,148,3356,64,574,549,2388,2391,276,3337,739,1854,1596,26,1690,2404,3493,1437,107	-0.4920008457387619,-0.5921770650124923,1.118191455601226,-0.6930805097254553,-0.03347806686168351,1.4760406150941263,0.5366787829519797,0.845141841466991,1.027635769907882,2.058127752852981,-0.0012581004565036626,0.19067127264620573,0.845141841466991,-0.5587053640309138,-0.03347806686168351,0.09500082791205905,0.19067127264620573,0.9366227945511973,-0.6257295573052645,1.5644560394229112,-0.931491220478586,2.512197372488192,0.5677772700633923,0.5988184783374502,-0.2609563355332265,-0.2609563355332265,1.0578712931665288,-0.8971691305719629,0.44303477605405855,-0.06576592628969985,0.030894617027511038,3.9014137223503935,-0.0012581004565036626,-0.2609563355332265,-1.209424370050621,0.09500082791205905,1.943054324684516	3643
Proximal muscle weakness	20	65	2.4969378761998287	0.0125270900753196	Q99720,P51114,Q8TD16,P02545,P06753,Q13126,P10253,Q00796,O60313,Q7Z406,Q9BPX6,Q96RR1,Q13049,P50336,P00846,Q7LG56,Q9H9S5,Q8NAT1,Q8NFF5,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,504,272,265,394,20,266,156,529,300,320,319,188,313,74,464,347,480,382,125	2049,529,2136,3404,791,1782,74,265,3450,394,125,2142,1376,266,3257,3623,2331,2332,3406,1878,1796,2927,944,753,754,1544,2711,313,849,1155,504,2073,2242,2349,156,2358,188,20,1992,3473,959,2087,2529,1165,1039,1320,464,2606,300,3047,480,382,2538,272,976,813,319,2,320,577,1581,3181,347,2960,1068	-0.16304347134508207,0.5988184783374502,-0.19560956934146895,-1.0350054838275398,0.3803099800917596,-0.06576592628969985,2.371337868662573,1.0578712931665288,-1.1393655482262741,0.7838890695289682,1.7400910153055076,-0.19560956934146895,0.09500082791205905,1.0578712931665288,-0.8287924672030076,-2.7252579017752425,-0.2609563355332265,-0.2609563355332265,-1.0350054838275398,-0.098122333905974,-0.06576592628969985,-0.5587053640309138,0.2857692407025649,0.4117022638315761,0.4117022638315761,0.030894617027511038,-0.42560918711049844,0.9670119136618348,0.34885740302862467,0.19067127264620573,0.6298028841948623,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,1.5350292358486646,-0.2609563355332265,1.387215394486587,4.39950530014643,-0.13054795621506413,-1.174345720866778,0.2857692407025649,-0.16304347134508207,-0.3265940252928932,0.19067127264620573,0.25413257026133235,0.12695555655645674,0.6916031594494587,-0.3595238272390506,0.9973494401983068,-0.6257295573052645,0.6607309570482511,0.8145422833591529,-0.3265940252928932,1.0578712931665288,0.2857692407025649,0.3803099800917596,0.9670119136618348,8.21990109917503,0.9670119136618348,0.5677772700633923,0.030894617027511038,-0.726880811724572,0.9061816816409076,-0.5587053640309138,0.25413257026133235	3643
Limb muscle weakness	18	89	2.491181346647972	0.0127319116527802	Q9NR77,Q99720,Q8N0X7,P00846,Q7RTS9,Q7Z406,Q14203,Q14739,P02545,P06753,O75298,Q13126,P39210,Q96RR1,Q13049,P07196,P50336,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,421,74,11,300,415,416,265,394,393,20,267,319,188,125,313,156	2210,646,2049,746,2212,2504,393,2417,791,74,265,2054,394,125,3151,2142,3256,2331,1878,753,592,1544,2431,2711,267,2232,2662,2432,1800,313,849,1155,2156,2073,2242,2716,1387,2349,2880,797,2585,156,1989,801,897,188,20,3473,959,415,2087,2529,416,566,964,2091,1165,1096,2889,1039,2363,1320,3502,1825,2946,464,11,300,3047,3393,421,976,813,2286,3231,2830,2622,1675,319,1053,3176,2,577,1581,32,3519,2960,608,1068	-0.22824695247054547,0.47430803058067816,-0.16304347134508207,0.4117022638315761,-0.22824695247054547,-0.3265940252928932,0.7838890695289682,-0.29373844618932715,0.3803099800917596,2.371337868662573,1.0578712931665288,-0.16304347134508207,0.7838890695289682,1.7400910153055076,-0.726880811724572,-0.19560956934146895,-0.8287924672030076,-0.2609563355332265,-0.098122333905974,0.4117022638315761,0.5366787829519797,0.030894617027511038,-0.29373844618932715,-0.42560918711049844,1.0578712931665288,-0.22824695247054547,-0.3925286203228279,-0.29373844618932715,-0.06576592628969985,0.9670119136618348,0.34885740302862467,0.19067127264620573,-0.19560956934146895,-0.16304347134508207,-0.22824695247054547,-0.42560918711049844,0.09500082791205905,-0.2609563355332265,-0.525313577596298,0.3803099800917596,-0.3595238272390506,1.5350292358486646,-0.13054795621506413,0.3803099800917596,0.31734400267200297,1.387215394486587,4.39950530014643,-1.174345720866778,0.2857692407025649,0.7531817696547146,-0.16304347134508207,-0.3265940252928932,0.7531817696547146,0.5677772700633923,0.2857692407025649,-0.16304347134508207,0.19067127264620573,0.2224334357534765,-0.525313577596298,0.25413257026133235,-0.2609563355332265,0.12695555655645674,-1.244601121096576,-0.06576592628969985,-0.5587053640309138,0.6916031594494587,5.543953911878619,0.9973494401983068,-0.6257295573052645,-1.0004082879139022,0.7531817696547146,0.2857692407025649,0.3803099800917596,-0.22824695247054547,-0.7947358122572576,-0.4920008457387619,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,0.25413257026133235,-0.726880811724572,8.21990109917503,0.5677772700633923,0.030894617027511038,3.6085359292973544,-1.2798752825252815,-0.5587053640309138,0.5366787829519797,0.25413257026133235	3643
Positive regulation of production of molecular mediator of immune response	10	26	2.4891657351438705	0.0128043260618724	P02786,Q7Z434,P30511,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0	Processes and pathways	GO Biological process	msigdb_gobp	409,420,138,15,143,590,87,429,522,227	2502,87,409,590,2509,15,1878,138,2229,1548,143,1727,2526,2535,969,420,2178,1923,914,1928,3235,522,638,2394,227,429	-0.3265940252928932,2.11542427763213,0.7531817696547146,0.5366787829519797,-0.3265940252928932,4.964849362308119,-0.098122333905974,1.623176179314646,-0.22824695247054547,0.030894617027511038,1.5938382520831849,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,0.7531817696547146,-0.19560956934146895,-0.098122333905974,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,0.7531817696547146	3643
Sphingolipid metabolic process	10	34	2.4890226753042666	0.0128094795648436	P16278,P07602,P50897,Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q96G23,P06280	Processes and pathways	GO Biological process	msigdb_gobp	155,69,72,330,28,85,251,227,159,153	746,2212,85,701,703,153,1013,69,3538,155,2869,1797,502,1968,72,2938,2166,3473,330,1900,905,809,28,159,426,2388,227,251,1758,2488,1432,1064,2847,1199	0.4117022638315761,-0.22824695247054547,2.144013371443563,0.44303477605405855,0.44303477605405855,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,1.5350292358486646,-0.525313577596298,-0.06576592628969985,0.6298028841948623,-0.13054795621506413,2.399583395405736,-0.5587053640309138,-0.19560956934146895,-1.174345720866778,0.9366227945511973,-0.098122333905974,0.31734400267200297,0.3803099800917596,3.768713037747525,1.5350292358486646,0.7531817696547146,-0.2609563355332265,1.2083001127798034,1.118191455601226,-0.03347806686168351,-0.29373844618932715,0.09500082791205905,0.25413257026133235,-0.4920008457387619,0.19067127264620573	3643
FAD/NAD(P)-binding domain superfamily [IPR036188]	6	21	2.486778535541416	0.0128905616933148	Q9UHG3,Q8NB78,O95831,P00390,Q96CU9,P50336	Sequence	InterPro Superfamily	interpro_homologous_superfamily	430,128,47,25,92,313	1864,47,25,2143,1798,753,1462,891,313,2935,2673,2774,2272,857,128,676,1415,92,2118,430,434	-0.098122333905974,3.0119856905575273,3.9014137223503935,-0.19560956934146895,-0.06576592628969985,0.4117022638315761,0.06298071889501843,0.31734400267200297,0.9670119136618348,-0.5587053640309138,-0.3925286203228279,-0.4587663248239629,-0.22824695247054547,0.34885740302862467,1.7109272480905777,0.47430803058067816,0.09500082791205905,2.0294198239892403,-0.16304347134508207,0.7531817696547146,0.7531817696547146	3643
Calcium ion import	9	17	2.486381903745848	0.0129049393656388	P21796,Q9NWR8,P16615,Q9H4I9,P14373,Q9BPX6,O75844,Q8IYU8,Q9NRA0	Processes and pathways	GO Biological process	msigdb_gobp	34,305,172,244,395,320,248,257,227	436,248,395,172,1084,34,2517,708,3079,257,2949,2468,320,244,227,305,608	0.7224199472328477,1.118191455601226,0.7838890695289682,1.4760406150941263,0.2224334357534765,3.528055524230381,-0.3265940252928932,0.44303477605405855,-0.6593637349435877,1.08805639508316,-0.5587053640309138,-0.29373844618932715,0.9670119136618348,1.1482768495977804,1.2083001127798034,0.9973494401983068,0.5366787829519797	3643
Disproportionate short stature	10	27	2.485357482809853	0.0129421396944147	O00116,P16278,Q9UHX1,Q8WVQ1,Q7RTS9,Q15392,O75718,Q96HY6,Q9Y366,Q9UBM7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	374,155,171,423,11,45,295,384,290,289	374,584,2412,295,3288,1377,155,2516,707,1086,2713,1403,416,900,45,2728,1172,3413,11,1500,423,2183,384,3001,289,171,290	0.8145422833591529,0.5366787829519797,-0.29373844618932715,0.9973494401983068,-0.8629365633590367,0.09500082791205905,1.5350292358486646,-0.3265940252928932,0.44303477605405855,0.2224334357534765,-0.42560918711049844,0.09500082791205905,0.7531817696547146,0.31734400267200297,3.1215736355280526,-0.42560918711049844,0.19067127264620573,-1.0350054838275398,5.543953911878619,0.06298071889501843,0.7531817696547146,-0.19560956934146895,0.8145422833591529,-0.5921770650124923,1.027635769907882,1.5055575321040489,1.027635769907882	3643
Immunity	16	81	2.4824422022515047	0.0130485234194259	Q9UQ84,P46379,P10321,Q8IV08,Q15233,O00584,Q9BY67,Q7Z434,Q9NZ08,P30511,Q8WXW3,P14174,O60858,P12956,Q9H2U1,P23246	Processes and pathways	Protein Atlas Biological process	protein_atlas_biological_process	33,3,532,73,567,103,304,420,245,138,468,15,80,83,522,375	1209,103,1365,1210,2410,2574,2794,80,2796,1616,1537,1872,2508,2863,590,1081,532,1704,83,1146,15,1083,1084,1878,2225,375,2762,616,138,1547,890,3,1888,797,1390,3038,1028,1310,1394,2441,1092,2084,715,1031,2814,1563,567,2531,2776,2455,1575,420,1828,73,2993,1111,468,2178,1258,1834,3311,2621,1261,1677,919,3002,304,3211,3479,522,2394,987,989,3242,1356,245,3063,926,33,1692,2496	0.15884550726049723,1.943054324684516,0.09500082791205905,0.15884550726049723,-0.29373844618932715,-0.3595238272390506,-0.4920008457387619,2.2579809707838456,-0.4920008457387619,-0.0012581004565036626,0.030894617027511038,-0.098122333905974,-0.3265940252928932,-0.525313577596298,0.5366787829519797,0.2224334357534765,0.5988184783374502,-0.03347806686168351,2.172563346869744,0.19067127264620573,4.964849362308119,0.2224334357534765,0.2224334357534765,-0.098122333905974,-0.22824695247054547,0.8145422833591529,-0.4587663248239629,0.5055225334229401,1.623176179314646,0.030894617027511038,0.31734400267200297,7.00443820279511,-0.098122333905974,0.3803099800917596,0.09500082791205905,-0.6257295573052645,0.25413257026133235,0.12695555655645674,0.09500082791205905,-0.29373844618932715,0.2224334357534765,-0.16304347134508207,0.44303477605405855,0.25413257026133235,-0.4920008457387619,0.030894617027511038,0.5677772700633923,-0.3265940252928932,-0.4587663248239629,-0.29373844618932715,0.030894617027511038,0.7531817696547146,-0.06576592628969985,2.399583395405736,-0.5921770650124923,0.2224334357534765,0.6916031594494587,-0.19560956934146895,0.15884550726049723,-0.06576592628969985,-0.8629365633590367,-0.3595238272390506,0.15884550726049723,-0.0012581004565036626,0.31734400267200297,-0.5921770650124923,0.9973494401983068,-0.7607655898218467,-1.174345720866778,0.6298028841948623,-0.2609563355332265,0.2857692407025649,0.2857692407025649,-0.7947358122572576,0.12695555655645674,1.1482768495977804,-0.6257295573052645,0.31734400267200297,3.6085359292973544,-0.0012581004565036626,-0.29373844618932715	3643
Biliary tract abnormality	7	30	2.482149344044698	0.0130592529635451	Q14108,P07602,O15078,P14174,O43681,O96028,Q9NUN5	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	255,69,194,15,118,87,123	194,118,1372,87,265,703,69,653,15,3437,1973,3155,1802,2238,2242,658,803,1562,255,416,1491,2378,2621,3212,2483,123,1064,1202,2789,1604	1.3575144142492008,1.7982903969638317,0.09500082791205905,2.11542427763213,1.0578712931665288,0.44303477605405855,2.427791890653298,0.47430803058067816,4.964849362308119,-1.104482929673742,-0.13054795621506413,-0.726880811724572,-0.06576592628969985,-0.22824695247054547,-0.22824695247054547,0.47430803058067816,0.3803099800917596,0.030894617027511038,1.08805639508316,0.7531817696547146,0.06298071889501843,-0.2609563355332265,-0.3595238272390506,-0.7607655898218467,-0.29373844618932715,1.7692119702003737,0.25413257026133235,0.19067127264620573,-0.4587663248239629,0.030894617027511038	3643
Incoordination	15	76	2.480622376534084	0.0131153234890812	Q9NR77,O00754,P07602,Q7RTS9,P00846,O75787,P06753,Q9H9S5,O14773,O43681,O75530,O75503,Q96RR1,Q9NUN5,Q6DKK2	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,435,69,11,74,296,394,347,391,118,86,24,319,123,190	1770,1862,435,391,1210,2571,118,2504,1078,3404,24,86,296,791,1454,74,703,394,69,3257,2331,1876,1796,844,753,2431,2232,1718,1885,2073,2242,2349,2880,797,3162,505,2721,2358,658,3473,959,2087,964,1165,668,2452,190,2729,1827,464,11,1493,1106,3276,1834,2622,728,2624,319,820,3178,3212,347,1429,3535,32,123,1849,1850,1064,1521,2913,1274,1853,1068,693	-0.06576592628969985,-0.098122333905974,0.7224199472328477,0.7838890695289682,0.15884550726049723,-0.3595238272390506,1.7982903969638317,-0.3265940252928932,0.2224334357534765,-1.0350054838275398,4.11230346222967,2.11542427763213,0.9973494401983068,0.3803099800917596,0.06298071889501843,2.371337868662573,0.44303477605405855,0.7838890695289682,2.427791890653298,-0.8287924672030076,-0.2609563355332265,-0.098122333905974,-0.06576592628969985,0.34885740302862467,0.4117022638315761,-0.29373844618932715,-0.22824695247054547,-0.03347806686168351,-0.098122333905974,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,-0.525313577596298,0.3803099800917596,-0.726880811724572,0.6298028841948623,-0.42560918711049844,-0.2609563355332265,0.47430803058067816,-1.174345720866778,0.2857692407025649,-0.16304347134508207,0.2857692407025649,0.19067127264620573,0.47430803058067816,-0.29373844618932715,1.387215394486587,-0.42560918711049844,-0.06576592628969985,0.6916031594494587,5.543953911878619,0.06298071889501843,0.2224334357534765,-0.8287924672030076,-0.06576592628969985,-0.3595238272390506,0.44303477605405855,-0.3595238272390506,0.9670119136618348,0.3803099800917596,-0.726880811724572,-0.7607655898218467,0.9061816816409076,0.09500082791205905,-1.3507131280591325,3.6085359292973544,1.7692119702003737,-0.06576592628969985,-0.06576592628969985,0.25413257026133235,0.06298071889501843,-0.525313577596298,0.15884550726049723,-0.06576592628969985,0.25413257026133235,0.47430803058067816	3643
Golgi apparatus	61	235	2.4718043766885907	0.0134433056692797	O15344,Q92896,Q9HC07,Q6NT16,Q7RTS9,Q8IXU6,Q8IZA0,O43493,Q8TD16,Q9HD45,Q86SX3,O60476,Q5KU26,O14976,Q5VW38,P05067,Q8IYS2,P16278,P11717,O00231,Q9HB40,Q8NCH0,Q8WVQ1,P22466,Q08379,O75071,Q9NPR9,Q02818,O60499,O15127,P50897,O00461,Q8NBJ4,Q8IWJ2,Q5VU43,Q93050,Q9H9S5,O43752,O60512,Q9H3P7,Q9BX67,P80303,Q969M3,Q8NBN3,Q9BRK5,O60637,Q6ZVM7,Q15012,Q5SRI9,Q9NX62,Q96CN9,P35606,O15260,Q99523,Q01082,P15291,O75955,P10586,O95456,Q8TBA6,A4D1U4	Localization	Protein Atlas Subcellular	protein_atlas_subcellular_location_all	253,136,405,10,11,12,141,142,272,277,271,264,396,392,23,29,157,155,154,278,35,422,423,38,414,40,48,65,196,195,72,70,75,465,208,82,347,454,85,523,488,93,356,225,96,220,381,353,478,231,368,474,108,114,365,112,249,119,250,383,246	1070,528,246,2569,1952,278,70,2133,1530,1445,392,1608,195,1002,1073,108,253,1003,2215,2962,2858,2859,142,3402,454,1533,264,1865,196,85,220,837,1217,40,3496,2412,3067,249,700,1140,250,2651,590,29,3319,653,119,3220,154,112,155,3070,1797,38,562,2801,2763,2340,1383,3199,474,2932,3116,1019,1628,1629,2713,795,1802,1155,1020,72,3386,1553,1302,3558,2241,2521,2243,1889,2768,3571,2254,93,2881,2591,1477,365,65,2938,2438,414,1159,1160,3620,3121,564,2444,1402,2941,3600,353,963,3205,3581,542,396,666,478,3602,2775,208,2679,23,3349,2452,2945,2001,10,3045,1905,3596,2776,1907,2821,971,2003,381,11,1575,629,271,1741,771,3624,810,2277,465,1179,12,1411,157,141,2280,3353,3306,2463,1329,75,225,422,3525,1746,383,272,1416,2829,423,677,515,136,2103,82,2612,2379,356,2613,1259,2181,368,3232,2951,3051,604,2543,2623,2185,2686,1505,1263,114,982,2952,3427,96,2294,1344,2909,1841,2296,488,1347,3237,3506,1268,2300,3239,1350,523,3554,2479,3213,2694,347,3214,35,405,1844,277,1193,48,2553,871,1125,3377,3183,737,231,1520,3604,2489,2400,3062,1946,2914,3008,1593,2851,927,2854,743,1362,832,1439,610	0.2224334357534765,0.5988184783374502,1.118191455601226,-0.3595238272390506,-0.13054795621506413,1.027635769907882,2.399583395405736,-0.19560956934146895,0.030894617027511038,0.06298071889501843,0.7838890695289682,-0.0012581004565036626,1.3575144142492008,0.25413257026133235,0.2224334357534765,1.914184390727662,1.08805639508316,0.25413257026133235,-0.22824695247054547,-0.5921770650124923,-0.525313577596298,-0.525313577596298,1.5938382520831849,-1.0350054838275398,0.6916031594494587,0.030894617027511038,1.0578712931665288,-0.098122333905974,1.3575144142492008,2.144013371443563,1.2083001127798034,0.34885740302862467,0.15884550726049723,3.2306497156014906,-1.244601121096576,-0.29373844618932715,-0.6593637349435877,1.118191455601226,0.44303477605405855,0.19067127264620573,1.118191455601226,-0.3925286203228279,0.5366787829519797,3.6353042018995785,-0.8971691305719629,0.47430803058067816,1.7982903969638317,-0.7947358122572576,1.5350292358486646,1.8563207862044178,1.5350292358486646,-0.6593637349435877,-0.06576592628969985,3.257840018273795,0.5677772700633923,-0.4920008457387619,-0.4587663248239629,-0.2609563355332265,0.09500082791205905,-0.7607655898218467,0.6607309570482511,-0.5587053640309138,-0.6930805097254553,0.25413257026133235,-0.0012581004565036626,-0.0012581004565036626,-0.42560918711049844,0.3803099800917596,-0.06576592628969985,0.19067127264620573,0.25413257026133235,2.399583395405736,-1.0004082879139022,0.030894617027511038,0.12695555655645674,-1.4935285643358234,-0.22824695247054547,-0.3265940252928932,-0.22824695247054547,-0.098122333905974,-0.4587663248239629,-1.5654960467228805,-0.22824695247054547,2.0006717808585845,-0.525313577596298,-0.3595238272390506,0.06298071889501843,0.845141841466991,2.4840986629825825,-0.5587053640309138,-0.29373844618932715,0.7531817696547146,0.19067127264620573,0.19067127264620573,-2.3803772184572165,-0.6930805097254553,0.5677772700633923,-0.29373844618932715,0.09500082791205905,-0.5587053640309138,-1.8938214246167355,0.8756881681175116,0.2857692407025649,-0.7607655898218467,-1.63783022894056,0.5988184783374502,0.7838890695289682,0.47430803058067816,0.6607309570482511,-1.8938214246167355,-0.4587663248239629,1.2979715997804608,-0.3925286203228279,4.295431147653506,-0.931491220478586,-0.29373844618932715,-0.5587053640309138,-0.13054795621506413,5.593769792208002,-0.6257295573052645,-0.098122333905974,-1.7835801457881182,-0.4587663248239629,-0.098122333905974,-0.4920008457387619,0.2857692407025649,-0.13054795621506413,0.8145422833591529,5.543953911878619,0.030894617027511038,0.5055225334229401,1.0578712931665288,-0.03347806686168351,0.4117022638315761,-2.763967375035913,0.3803099800917596,-0.22824695247054547,0.6916031594494587,0.19067127264620573,5.444068869967951,0.09500082791205905,1.5350292358486646,1.623176179314646,-0.22824695247054547,-0.931491220478586,-0.8629365633590367,-0.29373844618932715,0.12695555655645674,2.371337868662573,1.2083001127798034,0.7531817696547146,-1.315246174406957,-0.03347806686168351,0.8145422833591529,1.0578712931665288,0.09500082791205905,-0.4920008457387619,0.7531817696547146,0.47430803058067816,0.6298028841948623,1.6524701228970238,-0.16304347134508207,2.2010744460285183,-0.3595238272390506,-0.2609563355332265,0.8756881681175116,-0.3595238272390506,0.15884550726049723,-0.19560956934146895,0.845141841466991,-0.7947358122572576,-0.5587053640309138,-0.6257295573052645,0.5366787829519797,-0.3265940252928932,-0.3595238272390506,-0.19560956934146895,-0.3925286203228279,0.06298071889501843,0.15884550726049723,1.8563207862044178,0.2857692407025649,-0.5587053640309138,-1.069696640684267,2.0006717808585845,-0.22824695247054547,0.12695555655645674,-0.525313577596298,-0.06576592628969985,-0.22824695247054547,0.6607309570482511,0.12695555655645674,-0.7947358122572576,-1.244601121096576,0.15884550726049723,-0.22824695247054547,-0.7947358122572576,0.12695555655645674,0.6298028841948623,-1.4576838354723742,-0.29373844618932715,-0.7607655898218467,-0.3925286203228279,0.9061816816409076,-0.7607655898218467,3.447308651903207,0.7838890695289682,-0.06576592628969985,1.0578712931665288,0.19067127264620573,3.0119856905575273,-0.3265940252928932,0.34885740302862467,0.2224334357534765,-0.9659039071751861,-0.726880811724572,0.44303477605405855,1.1783129469800828,0.06298071889501843,-1.8938214246167355,-0.29373844618932715,-0.2609563355332265,-0.6257295573052645,-0.098122333905974,-0.525313577596298,-0.5921770650124923,0.030894617027511038,-0.4920008457387619,0.31734400267200297,-0.4920008457387619,0.44303477605405855,0.12695555655645674,0.3803099800917596,0.09500082791205905,0.5366787829519797	3643
Proteasome core complex	6	15	2.469557821552609	0.0135280153970891	P28070,P28074,P20618,P28072,Q99436,P49721	Localization	GO Cellular component	msigdb_gocc	164,41,137,146,121,60	3142,137,2762,1461,1621,2802,3222,164,146,41,2878,60,283,2013,121	-0.726880811724572,1.623176179314646,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.525313577596298,2.5402599154147643,1.027635769907882,-0.13054795621506413,1.7692119702003737	3643
Neuron apoptotic process	13	49	2.463366124160621	0.0137639286061099	Q99720,Q01105,P50897,Q13464,Q96A26,O95831,Q15375,P31751,P07196,Q99538,Q969N2,Q92542,P05067	Processes and pathways	GO Biological process	msigdb_gobp	2,505,72,328,243,47,418,364,125,520,318,317,29	1606,3495,2861,881,885,47,703,3291,2863,1288,29,2509,125,1457,653,1791,840,364,3520,708,1548,3155,2582,757,2236,1800,72,1301,2584,1723,2806,3079,505,506,328,1401,567,418,317,318,243,3332,3177,520,2,1056,779,1855,1768	-0.0012581004565036626,-1.244601121096576,-0.525313577596298,0.31734400267200297,0.31734400267200297,3.0119856905575273,0.44303477605405855,-0.8629365633590367,-0.525313577596298,0.12695555655645674,3.6353042018995785,-0.3265940252928932,1.7400910153055076,0.06298071889501843,0.47430803058067816,-0.06576592628969985,0.34885740302862467,0.845141841466991,-1.315246174406957,0.44303477605405855,0.030894617027511038,-0.726880811724572,-0.3595238272390506,0.4117022638315761,-0.22824695247054547,-0.06576592628969985,2.399583395405736,0.12695555655645674,-0.3595238272390506,-0.03347806686168351,-0.4920008457387619,-0.6593637349435877,0.6298028841948623,0.6298028841948623,0.9366227945511973,0.09500082791205905,0.5677772700633923,0.7531817696547146,0.9670119136618348,0.9670119136618348,1.1482768495977804,-0.8971691305719629,-0.726880811724572,0.6298028841948623,8.21990109917503,0.25413257026133235,0.4117022638315761,-0.06576592628969985,-0.03347806686168351	3643
Abnormal femoral neck head morphology	17	51	2.4612142742916325	0.0138467640691206	P16278,O00754,P55011,P04066,Q8WVQ1,Q96L58,Q9Y487,Q7RTS9,O75718,Q14739,P02545,O95831,O75431,O75530,O75844,P11274,Q96HY6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,435,440,228,423,303,43,11,295,416,265,47,213,86,248,338,384	834,435,1958,2412,213,86,295,248,47,265,228,338,155,2337,2147,3197,707,3031,2933,3117,2713,1802,3626,440,2434,416,900,806,1038,2364,1905,2003,3413,11,2458,423,2612,1048,1112,384,303,2185,3052,3003,3096,524,2041,3012,43,1069,693	0.34885740302862467,0.7224199472328477,-0.13054795621506413,-0.29373844618932715,1.2382387072449188,2.11542427763213,0.9973494401983068,1.118191455601226,3.0119856905575273,1.0578712931665288,1.1783129469800828,0.9061816816409076,1.5350292358486646,-0.2609563355332265,-0.19560956934146895,-0.7607655898218467,0.44303477605405855,-0.6257295573052645,-0.5587053640309138,-0.6930805097254553,-0.42560918711049844,-0.06576592628969985,-2.919565762049335,0.7224199472328477,-0.29373844618932715,0.7531817696547146,0.31734400267200297,0.3803099800917596,0.25413257026133235,-0.2609563355332265,-0.098122333905974,-0.13054795621506413,-1.0350054838275398,5.543953911878619,-0.29373844618932715,0.7531817696547146,-0.3595238272390506,0.25413257026133235,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.19560956934146895,-0.6257295573052645,-0.5921770650124923,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,-0.5921770650124923,3.2306497156014906,0.25413257026133235,0.47430803058067816	3643
Regulation of ph	8	24	2.457297687164824	0.0139986633699913	P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7	Processes and pathways	GO Biological process	msigdb_gobp	72,405,43,296,82,251,24,361	24,296,1962,2141,1144,3322,3197,72,2156,459,2587,1036,965,1914,1331,82,2180,405,251,1274,2401,43,3315,361	4.11230346222967,0.9973494401983068,-0.13054795621506413,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.3595238272390506,0.25413257026133235,0.2857692407025649,-0.098122333905974,0.12695555655645674,2.2010744460285183,-0.19560956934146895,0.7838890695289682,1.118191455601226,0.15884550726049723,-0.2609563355332265,3.2306497156014906,-0.8629365633590367,0.8756881681175116	3643
Regulation of cellular ph	8	24	2.457297687164824	0.0139986633699913	P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7	Processes and pathways	GO Biological process	msigdb_gobp	72,405,43,296,82,251,24,361	24,296,1962,2141,1144,3322,3197,72,2156,459,2587,1036,965,1914,1331,82,2180,405,251,1274,2401,43,3315,361	4.11230346222967,0.9973494401983068,-0.13054795621506413,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.3595238272390506,0.25413257026133235,0.2857692407025649,-0.098122333905974,0.12695555655645674,2.2010744460285183,-0.19560956934146895,0.7838890695289682,1.118191455601226,0.15884550726049723,-0.2609563355332265,3.2306497156014906,-0.8629365633590367,0.8756881681175116	3643
Biological adhesion	43	200	2.4554229206947578	0.014071892683203	P07942,Q08380,Q9HCL2,Q8WTV0,Q9BQT9,Q13136,Q92797,Q9UM22,O00192,Q9UQB8,P05067,P46939,P35579,Q9BY67,Q96JJ3,P02786,P16615,P80404,O75116,Q15375,Q9UBT7,P30825,P00813,O14936,P23396,P12814,Q13464,O43707,Q13641,Q14168,Q96F07,P09493,P78536,Q9BX67,P41440,P11274,Q14185,Q9NUQ9,P35580,P15291,P57105,O75955,P10586	Processes and pathways	GO Biological process	msigdb_gobp	126,254,5,8,275,269,149,22,389,26,29,281,280,304,302,409,172,413,293,418,323,54,56,436,437,308,328,325,329,211,344,215,216,488,90,338,94,102,222,112,238,249,119	2916,1207,389,1952,3065,2792,3610,1606,436,1607,1072,1448,2215,325,789,1076,1959,293,3496,1005,2136,249,1783,1786,2757,56,409,2508,590,3149,29,3218,2141,1012,3150,3191,126,1457,3069,1081,215,119,1377,3256,3257,338,308,3468,112,941,3552,3629,172,942,1084,1620,843,2337,2063,437,501,2658,1968,54,592,2709,2874,534,708,2068,280,222,889,2932,1547,90,3325,2712,3117,281,3440,1630,1801,1155,3344,2240,1554,1633,238,2244,1723,1890,3268,3368,3409,3077,1557,1156,3120,2162,216,3038,413,1477,1988,3079,2259,2938,1815,1310,1029,3270,254,1395,1727,1398,2940,803,269,1993,1994,328,1896,329,1031,1033,3225,2267,211,94,1402,1315,1996,1166,418,3541,2601,2271,855,1097,904,1246,3169,1323,8,1184,1331,2015,1334,3173,149,978,1049,2619,344,574,1186,1339,2621,302,863,2737,275,2549,488,304,489,2389,1513,3057,3533,3213,2116,1269,5,1192,2742,102,1587,1686,783,1200,1760,323,2037,990,1361,22,2636,928,26,1362,2566,2206,2496,1859,1204,1951,1443,555	-0.5587053640309138,0.15884550726049723,0.7838890695289682,-0.13054795621506413,-0.6593637349435877,-0.4920008457387619,-2.1540615170130093,-0.0012581004565036626,0.7224199472328477,-0.0012581004565036626,0.2224334357534765,0.06298071889501843,-0.22824695247054547,0.9366227945511973,0.3803099800917596,0.2224334357534765,-0.13054795621506413,0.9973494401983068,-1.244601121096576,0.25413257026133235,-0.19560956934146895,1.118191455601226,-0.06576592628969985,-0.06576592628969985,-0.4587663248239629,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.726880811724572,3.6353042018995785,-0.7947358122572576,-0.19560956934146895,0.25413257026133235,-0.726880811724572,-0.7607655898218467,1.7109272480905777,0.06298071889501843,-0.6593637349435877,0.2224334357534765,1.2382387072449188,1.7982903969638317,0.09500082791205905,-0.8287924672030076,-0.8287924672030076,0.9061816816409076,0.9670119136618348,-1.174345720866778,1.8563207862044178,0.2857692407025649,-1.4576838354723742,-2.997816021189173,1.4760406150941263,0.2857692407025649,0.2224334357534765,-0.0012581004565036626,0.34885740302862467,-0.2609563355332265,-0.16304347134508207,0.7224199472328477,0.6298028841948623,-0.3925286203228279,-0.13054795621506413,2.707887319665007,0.5366787829519797,-0.42560918711049844,-0.525313577596298,0.5988184783374502,0.44303477605405855,-0.16304347134508207,1.027635769907882,1.2083001127798034,0.31734400267200297,-0.5587053640309138,0.030894617027511038,2.058127752852981,-0.8971691305719629,-0.42560918711049844,-0.6930805097254553,1.027635769907882,-1.104482929673742,-0.0012581004565036626,-0.06576592628969985,0.19067127264620573,-0.931491220478586,-0.22824695247054547,0.030894617027511038,-0.0012581004565036626,1.1482768495977804,-0.22824695247054547,-0.03347806686168351,-0.098122333905974,-0.8287924672030076,-0.9659039071751861,-1.0350054838275398,-0.6593637349435877,0.030894617027511038,0.19067127264620573,-0.6930805097254553,-0.19560956934146895,1.2382387072449188,-0.6257295573052645,0.7531817696547146,0.06298071889501843,-0.13054795621506413,-0.6593637349435877,-0.22824695247054547,-0.5587053640309138,-0.06576592628969985,0.12695555655645674,0.25413257026133235,-0.8287924672030076,1.08805639508316,0.09500082791205905,-0.03347806686168351,0.09500082791205905,-0.5587053640309138,0.3803099800917596,1.0578712931665288,-0.13054795621506413,-0.13054795621506413,0.9366227945511973,-0.098122333905974,0.9366227945511973,0.25413257026133235,0.25413257026133235,-0.7947358122572576,-0.22824695247054547,1.268129085929357,2.0006717808585845,0.09500082791205905,0.12695555655645674,-0.13054795621506413,0.19067127264620573,0.7531817696547146,-1.3862754857551036,-0.3595238272390506,-0.22824695247054547,0.34885740302862467,0.2224334357534765,0.31734400267200297,0.15884550726049723,-0.726880811724572,0.12695555655645674,5.940175937290734,0.19067127264620573,0.12695555655645674,-0.13054795621506413,0.12695555655645674,-0.726880811724572,1.5644560394229112,0.2857692407025649,0.25413257026133235,-0.3595238272390506,0.9061816816409076,0.5677772700633923,0.19067127264620573,0.12695555655645674,-0.3595238272390506,0.9973494401983068,0.34885740302862467,-0.42560918711049844,1.0578712931665288,-0.3265940252928932,0.6607309570482511,0.9973494401983068,0.6607309570482511,-0.2609563355332265,0.06298071889501843,-0.6257295573052645,-1.3507131280591325,-0.7607655898218467,-0.16304347134508207,0.15884550726049723,6.233993929662534,0.19067127264620573,-0.42560918711049844,1.9718833674139287,0.030894617027511038,-0.0012581004565036626,0.4117022638315761,0.19067127264620573,-0.03347806686168351,0.9670119136618348,-0.13054795621506413,0.2857692407025649,0.12695555655645674,4.373525061543824,-0.3595238272390506,0.31734400267200297,3.9014137223503935,0.12695555655645674,-0.3265940252928932,-0.19560956934146895,-0.29373844618932715,-0.06576592628969985,0.19067127264620573,-0.098122333905974,0.09500082791205905,0.5988184783374502	3643
Phospholipid binding	29	106	2.45365604367249	0.0141412170279222	Q92538,Q13045,Q14108,Q8WTV0,Q9H1P3,O14773,Q9UM22,O00291,Q8NCC3,Q9Y5X2,O60313,P21796,Q06481,Q96L92,P20073,P07602,P50897,P45880,Q9Y4G8,O14523,O60749,Q15075,Q9Y5X1,Q53T59,Q01082,Q9NS86,O95219,Q9NWW5,Q6ZVM7	Functions	GO Molecular function	msigdb_gomf	515,507,255,8,549,391,22,390,28,433,529,34,39,575,560,69,72,78,81,453,588,354,107,366,365,117,235,251,381	1206,390,834,2322,453,391,1774,2571,3101,2216,2963,1004,529,1213,588,2700,1367,235,1787,2508,3191,69,1080,3106,1081,2144,3023,3591,560,34,1797,1381,592,3261,2431,78,3035,709,2934,72,3265,1302,3558,2163,365,39,3411,507,2596,2528,1030,255,2088,1163,2530,354,902,366,666,1572,381,1494,1911,2372,1410,2948,28,3477,8,515,1921,3308,1049,575,3179,2999,2688,2114,984,3212,1424,549,2479,3213,2116,117,2695,251,1432,1064,1944,3008,2308,1854,22,3285,1596,1855,3585,1437,2206,81,107,433,2407,1525	0.15884550726049723,0.7838890695289682,0.34885740302862467,-0.2609563355332265,0.6916031594494587,0.7838890695289682,-0.06576592628969985,-0.3595238272390506,-0.6930805097254553,-0.22824695247054547,-0.5921770650124923,0.25413257026133235,0.5988184783374502,0.15884550726049723,0.5366787829519797,-0.42560918711049844,0.09500082791205905,1.1482768495977804,-0.06576592628969985,-0.3265940252928932,-0.7607655898218467,2.427791890653298,0.2224334357534765,-0.6930805097254553,0.2224334357534765,-0.19560956934146895,-0.6257295573052645,-1.7470088834303552,0.5677772700633923,3.528055524230381,-0.06576592628969985,0.09500082791205905,0.5366787829519797,-0.8287924672030076,-0.29373844618932715,2.286376867508823,-0.6257295573052645,0.44303477605405855,-0.5587053640309138,2.399583395405736,-0.8287924672030076,0.12695555655645674,-1.4935285643358234,-0.19560956934146895,0.845141841466991,3.257840018273795,-1.0350054838275398,0.6298028841948623,-0.3595238272390506,-0.3265940252928932,0.25413257026133235,1.08805639508316,-0.16304347134508207,0.19067127264620573,-0.3265940252928932,0.8756881681175116,0.31734400267200297,0.845141841466991,0.47430803058067816,0.030894617027511038,0.8145422833591529,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.09500082791205905,-0.5587053640309138,3.768713037747525,-1.174345720866778,5.940175937290734,0.6298028841948623,-0.098122333905974,-0.8629365633590367,0.25413257026133235,0.5677772700633923,-0.726880811724572,-0.5921770650124923,-0.3925286203228279,-0.16304347134508207,0.2857692407025649,-0.7607655898218467,0.09500082791205905,0.5988184783374502,-0.29373844618932715,-0.7607655898218467,-0.16304347134508207,1.8273265764439528,-0.3925286203228279,1.118191455601226,0.09500082791205905,0.25413257026133235,-0.098122333905974,-0.5921770650124923,-0.22824695247054547,-0.06576592628969985,4.373525061543824,-0.8287924672030076,0.030894617027511038,-0.06576592628969985,-1.6741333670170677,0.09500082791205905,-0.19560956934146895,2.2579809707838456,1.943054324684516,0.7531817696547146,-0.2609563355332265,0.06298071889501843	3643
Abnormality of the peripheral nervous system	23	108	2.446171461562078	0.0144382318638431	Q99720,Q71SY5,P02545,P39210,O00192,Q9UBM7,Q96EK5,P06280,Q00796,Q9NR77,Q7Z406,O95831,P42892,Q96RR1,P50336,P20700,P07602,O15078,Q8WXW3,P41440,O43681,P07196,Q9GZY8	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,144,265,267,389,289,425,153,156,32,300,47,53,319,313,310,69,194,468,90,118,125,130	389,1210,194,746,2212,585,118,1696,1776,529,1078,881,791,1454,1456,47,265,703,153,125,69,3538,3572,1878,1222,310,2515,1713,1971,3296,2764,2711,267,1546,2662,90,53,890,2933,1467,1800,313,1155,2156,1301,2238,2074,2242,2349,3408,3471,156,1989,2721,955,658,3328,3490,2087,899,964,2091,2887,627,1825,1407,2946,1827,144,464,300,859,673,2608,2734,468,813,1334,2100,425,2835,728,2624,1675,319,1053,3177,2,3561,130,3212,821,3533,2482,32,2556,988,2034,1064,3243,1521,289,2490,1853,2565,1767,1604,693	0.7838890695289682,0.15884550726049723,1.3575144142492008,0.4117022638315761,-0.22824695247054547,0.5366787829519797,1.7982903969638317,-0.03347806686168351,-0.06576592628969985,0.5988184783374502,0.2224334357534765,0.31734400267200297,0.3803099800917596,0.06298071889501843,0.06298071889501843,3.0119856905575273,1.0578712931665288,0.44303477605405855,1.5350292358486646,1.7400910153055076,2.427791890653298,-1.3862754857551036,-1.6016175956969314,-0.098122333905974,0.15884550726049723,0.9670119136618348,-0.3265940252928932,-0.03347806686168351,-0.13054795621506413,-0.8629365633590367,-0.4587663248239629,-0.42560918711049844,1.0578712931665288,0.030894617027511038,-0.3925286203228279,2.058127752852981,2.763483088965262,0.31734400267200297,-0.5587053640309138,0.06298071889501843,-0.06576592628969985,0.9670119136618348,0.19067127264620573,-0.19560956934146895,0.12695555655645674,-0.22824695247054547,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,-1.0350054838275398,-1.174345720866778,1.5350292358486646,-0.13054795621506413,-0.42560918711049844,0.2857692407025649,0.47430803058067816,-0.8971691305719629,-1.209424370050621,-0.16304347134508207,0.31734400267200297,0.2857692407025649,-0.16304347134508207,-0.525313577596298,0.5055225334229401,-0.06576592628969985,0.09500082791205905,-0.5587053640309138,-0.06576592628969985,1.5938382520831849,0.6916031594494587,0.9973494401983068,0.34885740302862467,0.47430803058067816,-0.3595238272390506,-0.42560918711049844,0.6916031594494587,0.3803099800917596,0.12695555655645674,-0.16304347134508207,0.7531817696547146,-0.4920008457387619,0.44303477605405855,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,0.25413257026133235,-0.726880811724572,8.21990109917503,-1.4935285643358234,1.7109272480905777,-0.7607655898218467,0.3803099800917596,-1.3507131280591325,-0.29373844618932715,3.6085359292973544,-0.3265940252928932,0.2857692407025649,-0.13054795621506413,0.25413257026133235,-0.7947358122572576,0.06298071889501843,1.027635769907882,-0.29373844618932715,-0.06576592628969985,-0.3265940252928932,-0.03347806686168351,0.030894617027511038,0.47430803058067816	3643
Positive regulation of cytokine production involved in immune response	7	13	2.4364098240913408	0.0148338675397914	Q7Z434,P30511,P14174,Q01650,Q9NY93,Q9H2U1,Q9NRA0	Processes and pathways	GO Biological process	msigdb_gobp	420,138,15,143,429,522,227	2502,590,15,1878,138,143,420,2178,1923,522,2394,227,429	-0.3265940252928932,0.5366787829519797,4.964849362308119,-0.098122333905974,1.623176179314646,1.5938382520831849,0.7531817696547146,-0.19560956934146895,-0.098122333905974,0.6298028841948623,-0.2609563355332265,1.2083001127798034,0.7531817696547146	3643
Foot dorsiflexor weakness	9	33	2.4336213150208263	0.0149486251516552	Q9NR77,Q99720,Q9BQT8,Q7LG56,Q14739,P02545,P06753,P39210,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,2,577,464,416,265,394,267,125	2210,2049,746,2212,2504,791,265,2054,394,125,2711,267,2432,1800,2156,2242,1387,2349,2585,959,2529,416,566,2889,2363,1825,2946,464,2830,2,577,32,2960	-0.22824695247054547,-0.16304347134508207,0.4117022638315761,-0.22824695247054547,-0.3265940252928932,0.3803099800917596,1.0578712931665288,-0.16304347134508207,0.7838890695289682,1.7400910153055076,-0.42560918711049844,1.0578712931665288,-0.29373844618932715,-0.06576592628969985,-0.19560956934146895,-0.22824695247054547,0.09500082791205905,-0.2609563355332265,-0.3595238272390506,0.2857692407025649,-0.3265940252928932,0.7531817696547146,0.5677772700633923,-0.525313577596298,-0.2609563355332265,-0.06576592628969985,-0.5587053640309138,0.6916031594494587,-0.4920008457387619,8.21990109917503,0.5677772700633923,3.6085359292973544,-0.5587053640309138	3643
Production of molecular mediator of immune response	14	41	2.431134853174392	0.0150516112874883	Q9UQ84,P20585,Q96FV9,P02786,Q7Z434,P30511,Q9NQT5,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0	Processes and pathways	GO Biological process	msigdb_gobp	33,309,681,409,420,138,638,15,143,590,87,429,522,227	2502,1217,87,409,590,2509,653,3256,3513,15,1878,309,1148,138,2229,1548,1553,1390,143,1727,2526,1404,2535,969,1737,420,1256,2178,1923,681,914,1928,3235,3479,522,638,2394,227,429,33,1692	-0.3265940252928932,0.15884550726049723,2.11542427763213,0.7531817696547146,0.5366787829519797,-0.3265940252928932,0.47430803058067816,-0.8287924672030076,-1.2798752825252815,4.964849362308119,-0.098122333905974,0.9670119136618348,0.19067127264620573,1.623176179314646,-0.22824695247054547,0.030894617027511038,0.030894617027511038,0.09500082791205905,1.5938382520831849,-0.03347806686168351,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,0.15884550726049723,-0.19560956934146895,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,0.7531817696547146,3.6085359292973544,-0.0012581004565036626	3643
Regulation of response to external stimulus	37	150	2.425855382905603	0.0152723547247695	P30511,P14174,Q9UMX5,Q96G23,P05067,P60900,P19474,Q06481,Q9BY67,P28070,Q7Z434,P80404,P00813,O75592,O43657,O94874,O14936,P55011,Q15046,Q15233,Q13641,P12956,Q13573,P78536,Q9BX67,P11274,P80303,Q9NUQ9,Q96RK4,P51809,Q9NZ08,Q9NWH9,O95219,P10586,Q99538,O75844,P23246	Processes and pathways	GO Biological process	msigdb_gobp	138,15,27,159,29,283,36,39,304,164,420,413,56,186,557,558,436,440,566,567,329,83,88,216,488,338,93,102,519,476,245,371,235,119,520,248,375	1605,1606,2050,436,2211,2502,557,2860,2794,1614,3496,2796,3216,186,248,749,1698,558,1616,235,2053,56,3617,1872,703,2508,590,29,1789,1457,1081,119,338,1082,83,1146,15,942,1794,2427,36,2337,375,2762,616,3322,2658,164,3197,2928,3198,138,2874,3520,2342,3297,756,890,2712,1630,3344,476,1632,1888,440,797,3546,283,3160,1156,1390,216,3038,93,413,1235,2258,2938,1815,39,1310,1394,1395,1727,1479,2672,88,329,2814,566,567,2531,1037,2271,1404,1097,856,3579,3042,1098,2946,1909,420,1323,3530,1743,859,1180,2949,973,2828,1111,2683,2100,159,2621,2109,1261,2624,519,1506,3176,3177,520,1117,1752,2294,919,3236,488,304,3479,3533,2552,989,102,371,1356,245,828,784,1358,3184,3098,27,1855,927,1692,1132,2496	-0.0012581004565036626,-0.0012581004565036626,-0.16304347134508207,0.7224199472328477,-0.22824695247054547,-0.3265940252928932,0.5677772700633923,-0.525313577596298,-0.4920008457387619,-0.0012581004565036626,-1.244601121096576,-0.4920008457387619,-0.7947358122572576,1.387215394486587,1.118191455601226,0.4117022638315761,-0.03347806686168351,0.5677772700633923,-0.0012581004565036626,1.1482768495977804,-0.16304347134508207,2.6800374279695216,-2.342454069604444,-0.098122333905974,0.44303477605405855,-0.3265940252928932,0.5366787829519797,3.6353042018995785,-0.06576592628969985,0.06298071889501843,0.2224334357534765,1.7982903969638317,0.9061816816409076,0.2224334357534765,2.172563346869744,0.19067127264620573,4.964849362308119,0.2857692407025649,-0.06576592628969985,-0.29373844618932715,3.3662912544280115,-0.2609563355332265,0.8145422833591529,-0.4587663248239629,0.5055225334229401,-0.8971691305719629,-0.3925286203228279,1.5055575321040489,-0.7607655898218467,-0.5587053640309138,-0.7607655898218467,1.623176179314646,-0.525313577596298,-1.315246174406957,-0.2609563355332265,-0.8629365633590367,0.4117022638315761,0.31734400267200297,-0.42560918711049844,-0.0012581004565036626,-0.931491220478586,0.6607309570482511,-0.0012581004565036626,-0.098122333905974,0.7224199472328477,0.3803099800917596,-1.421932600442622,1.027635769907882,-0.726880811724572,0.19067127264620573,0.09500082791205905,1.2382387072449188,-0.6257295573052645,2.0006717808585845,0.7531817696547146,0.15884550726049723,-0.22824695247054547,-0.5587053640309138,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.09500082791205905,0.09500082791205905,-0.03347806686168351,0.06298071889501843,-0.3925286203228279,2.11542427763213,0.9366227945511973,-0.4920008457387619,0.5677772700633923,0.5677772700633923,-0.3265940252928932,0.25413257026133235,-0.22824695247054547,0.09500082791205905,0.2224334357534765,0.34885740302862467,-1.63783022894056,-0.6257295573052645,0.2224334357534765,-0.5587053640309138,-0.098122333905974,0.7531817696547146,0.12695555655645674,-1.3507131280591325,-0.03347806686168351,0.34885740302862467,0.19067127264620573,-0.5587053640309138,0.2857692407025649,-0.4920008457387619,0.2224334357534765,-0.3925286203228279,-0.16304347134508207,1.5350292358486646,-0.3595238272390506,-0.16304347134508207,0.15884550726049723,-0.3595238272390506,0.6298028841948623,0.06298071889501843,-0.726880811724572,-0.726880811724572,0.6298028841948623,0.2224334357534765,-0.03347806686168351,-0.22824695247054547,0.31734400267200297,-0.7947358122572576,0.6607309570482511,0.9973494401983068,-1.174345720866778,-1.3507131280591325,-0.3265940252928932,0.2857692407025649,1.9718833674139287,0.845141841466991,0.12695555655645674,1.1482768495977804,0.3803099800917596,0.4117022638315761,0.12695555655645674,-0.726880811724572,-0.6593637349435877,3.795309279757627,-0.06576592628969985,0.31734400267200297,-0.0012581004565036626,0.2224334357534765,-0.29373844618932715	3643
Abnormality of the metaphysis	14	61	2.424187920278857	0.0153426639187423	P16278,Q8WVQ1,Q96L58,Q9HC07,Q7RTS9,P48735,Q14739,O95831,Q13126,P51798,O75530,Q9Y366,P00813,Q96HY6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,423,303,405,11,339,416,47,20,460,86,290,56,384	834,2502,1865,1960,1005,86,1284,3288,1141,47,2651,56,1288,2055,3150,155,2337,2147,707,1973,2713,3557,339,1802,460,2434,2257,2937,1893,1815,1640,20,416,900,3389,1038,2364,2605,11,2458,1500,423,2612,2180,2183,384,303,728,3052,2195,405,1270,3096,3006,524,2956,1852,2400,744,290,3012	0.34885740302862467,-0.3265940252928932,-0.098122333905974,-0.13054795621506413,0.25413257026133235,2.11542427763213,0.12695555655645674,-0.8629365633590367,0.19067127264620573,3.0119856905575273,-0.3925286203228279,2.6800374279695216,0.12695555655645674,-0.16304347134508207,-0.726880811724572,1.5350292358486646,-0.2609563355332265,-0.19560956934146895,0.44303477605405855,-0.13054795621506413,-0.42560918711049844,-1.4935285643358234,0.9061816816409076,-0.06576592628969985,0.6916031594494587,-0.29373844618932715,-0.22824695247054547,-0.5587053640309138,-0.098122333905974,-0.06576592628969985,-0.0012581004565036626,4.39950530014643,0.7531817696547146,0.31734400267200297,-1.0004082879139022,0.25413257026133235,-0.2609563355332265,-0.3595238272390506,5.543953911878619,-0.29373844618932715,0.06298071889501843,0.7531817696547146,-0.3595238272390506,-0.19560956934146895,-0.19560956934146895,0.8145422833591529,0.9973494401983068,0.44303477605405855,-0.6257295573052645,-0.19560956934146895,0.7838890695289682,0.15884550726049723,-0.6593637349435877,-0.5921770650124923,0.6298028841948623,-0.5587053640309138,-0.06576592628969985,-0.2609563355332265,0.44303477605405855,1.027635769907882,-0.5921770650124923	3643
Coxa vara	6	16	2.422851333877683	0.0153992271697882	Q8WVQ1,Q9Y487,Q7RTS9,O75718,O95831,Q96HY6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	423,43,11,295,47,384	2412,295,47,2147,1802,2434,2364,11,423,2612,1112,384,3052,524,3012,43	-0.29373844618932715,0.9973494401983068,3.0119856905575273,-0.19560956934146895,-0.06576592628969985,-0.29373844618932715,-0.2609563355332265,5.543953911878619,0.7531817696547146,-0.3595238272390506,0.2224334357534765,0.8145422833591529,-0.6257295573052645,0.6298028841948623,-0.5921770650124923,3.2306497156014906	3643
Organic anion transmembrane transporter activity	17	37	2.4223871418848657	0.0154189142963765	P11166,Q86VD7,Q14728,O00400,O95563,Q9UBX3,Q9H2D1,P41440,Q9BQT8,P53985,Q8TB61,Q01650,Q15758,P30825,Q9HC21,Q9Y619,Q9Y6M7	Functions	GO Molecular function	msigdb_gomf	279,256,624,646,152,306,733,90,577,44,573,143,662,54,553,693,361	646,2793,1003,2754,1450,152,1873,704,279,2331,1145,54,2342,90,2073,44,143,2771,624,662,2274,2366,3456,256,1177,573,2906,2907,2292,577,733,1057,553,306,924,693,361	0.47430803058067816,-0.4920008457387619,0.25413257026133235,-0.4587663248239629,0.06298071889501843,1.5350292358486646,-0.098122333905974,0.44303477605405855,1.027635769907882,-0.2609563355332265,0.19067127264620573,2.707887319665007,-0.2609563355332265,2.058127752852981,-0.16304347134508207,3.1215736355280526,1.5938382520831849,-0.4587663248239629,0.5055225334229401,0.47430803058067816,-0.22824695247054547,-0.2609563355332265,-1.1393655482262741,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.525313577596298,-0.525313577596298,-0.22824695247054547,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.5988184783374502,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.8756881681175116	3643
Abnormality of femur morphology	22	76	2.4164860236335226	0.0156711278457775	O00116,Q7RTS9,P02545,P06280,P16278,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,O75718,Q14739,O95831,O00754,P55011,P07602,O75431,P51798,O75530,P11274,P04066,Q96HY6,O75844	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	374,11,265,153,155,171,423,303,43,295,416,47,435,440,69,213,460,86,338,228,384,248	374,834,3186,435,1210,585,1958,2412,213,86,295,248,1784,47,2651,265,703,228,1288,153,69,338,155,2145,2337,2147,3197,707,2764,3031,2933,3117,2713,1802,460,3626,1022,440,2434,416,900,806,1038,2728,2364,1905,2003,3413,11,2458,1664,1500,2610,423,2612,1048,1112,384,303,2185,3052,3001,3561,3003,3096,524,2034,3182,1064,1852,171,2041,3012,43,1069,693	0.8145422833591529,0.34885740302862467,-0.7607655898218467,0.7224199472328477,0.15884550726049723,0.5366787829519797,-0.13054795621506413,-0.29373844618932715,1.2382387072449188,2.11542427763213,0.9973494401983068,1.118191455601226,-0.06576592628969985,3.0119856905575273,-0.3925286203228279,1.0578712931665288,0.44303477605405855,1.1783129469800828,0.12695555655645674,1.5350292358486646,2.427791890653298,0.9061816816409076,1.5350292358486646,-0.19560956934146895,-0.2609563355332265,-0.19560956934146895,-0.7607655898218467,0.44303477605405855,-0.4587663248239629,-0.6257295573052645,-0.5587053640309138,-0.6930805097254553,-0.42560918711049844,-0.06576592628969985,0.6916031594494587,-2.919565762049335,0.25413257026133235,0.7224199472328477,-0.29373844618932715,0.7531817696547146,0.31734400267200297,0.3803099800917596,0.25413257026133235,-0.42560918711049844,-0.2609563355332265,-0.098122333905974,-0.13054795621506413,-1.0350054838275398,5.543953911878619,-0.29373844618932715,-0.0012581004565036626,0.06298071889501843,-0.3595238272390506,0.7531817696547146,-0.3595238272390506,0.25413257026133235,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.19560956934146895,-0.6257295573052645,-0.5921770650124923,-1.4935285643358234,-0.5921770650124923,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,-0.726880811724572,0.25413257026133235,-0.06576592628969985,1.5055575321040489,-0.13054795621506413,-0.5921770650124923,3.2306497156014906,0.25413257026133235,0.47430803058067816	3643
Negative regulation of cell population proliferation	23	112	2.4117007019803194	0.0158783100033093	P98175,O94788,Q71SY5,P02545,Q9Y366,Q96G23,P05067,Q9NR77,P22466,Q06481,Q15392,Q96DY7,Q13049,Q14457,Q96TA1,Q01664,Q13641,Q9Y4G8,P52756,P09493,P25705,P15291,P57105	Processes and pathways	GO Biological process	msigdb_gobp	134,9,144,265,290,159,29,32,38,39,45,61,188,189,333,327,329,81,210,215,237,112,238	3185,2134,2793,436,1774,2211,933,1611,350,2648,9,791,265,3291,1288,29,2055,215,653,2511,1377,112,3024,3570,2225,38,2064,237,2338,3615,2709,534,708,2229,2431,1296,1547,756,3325,849,210,3157,3345,238,3546,3120,1025,3038,134,1988,1560,327,2258,39,3080,1561,897,3620,2082,803,188,2168,2442,564,1562,1994,329,2267,1095,189,45,2725,1037,1404,3501,2728,1098,1171,2454,1909,144,2006,1108,1045,3173,2683,978,61,2619,159,1339,2621,333,3176,3235,2385,2687,1580,3561,489,2119,32,824,3431,582,3246,3184,1689,290,3248,81,555	-0.7607655898218467,-0.19560956934146895,-0.4920008457387619,0.7224199472328477,-0.06576592628969985,-0.22824695247054547,0.2857692407025649,-0.0012581004565036626,0.8756881681175116,-0.3925286203228279,5.816916168706705,0.3803099800917596,1.0578712931665288,-0.8629365633590367,0.12695555655645674,3.6353042018995785,-0.16304347134508207,1.2382387072449188,0.47430803058067816,-0.3265940252928932,0.09500082791205905,1.8563207862044178,-0.6257295573052645,-1.5654960467228805,-0.22824695247054547,3.257840018273795,-0.16304347134508207,1.1482768495977804,-0.2609563355332265,-2.2291720974867153,-0.42560918711049844,0.5988184783374502,0.44303477605405855,-0.22824695247054547,-0.29373844618932715,0.12695555655645674,0.030894617027511038,0.4117022638315761,-0.8971691305719629,0.34885740302862467,1.268129085929357,-0.726880811724572,-0.931491220478586,1.1482768495977804,-1.421932600442622,-0.6930805097254553,0.25413257026133235,-0.6257295573052645,1.6524701228970238,-0.13054795621506413,0.030894617027511038,0.9366227945511973,-0.22824695247054547,3.257840018273795,-0.6593637349435877,0.030894617027511038,0.31734400267200297,-2.3803772184572165,-0.16304347134508207,0.3803099800917596,1.387215394486587,-0.19560956934146895,-0.29373844618932715,0.5677772700633923,0.030894617027511038,-0.13054795621506413,0.9366227945511973,-0.22824695247054547,0.2224334357534765,1.387215394486587,3.1215736355280526,-0.42560918711049844,0.25413257026133235,0.09500082791205905,-1.244601121096576,-0.42560918711049844,0.2224334357534765,0.19067127264620573,-0.29373844618932715,-0.098122333905974,1.5938382520831849,-0.13054795621506413,0.2224334357534765,0.25413257026133235,-0.726880811724572,-0.3925286203228279,0.2857692407025649,2.5402599154147643,-0.3595238272390506,1.5350292358486646,0.12695555655645674,-0.3595238272390506,0.9366227945511973,-0.726880811724572,-0.7947358122572576,-0.2609563355332265,-0.3925286203228279,0.030894617027511038,-1.4935285643358234,0.6607309570482511,-0.16304347134508207,3.6085359292973544,0.3803099800917596,-1.069696640684267,0.5677772700633923,-0.7947358122572576,-0.726880811724572,-0.0012581004565036626,1.027635769907882,-0.7947358122572576,2.2579809707838456,0.5988184783374502	3643
Tetrapyrrole binding	6	23	2.408937900920556	0.0159990199979553	Q16850,O15173,P30519,O43169,Q8WUJ1,Q9NUN5	Functions	GO Molecular function	msigdb_gomf	67,199,14,263,49,123	932,199,263,2705,1618,653,2428,14,948,67,1492,286,49,724,1337,820,3561,2693,1193,492,1061,123,609	0.2857692407025649,1.327766595224347,1.0578712931665288,-0.42560918711049844,-0.0012581004565036626,0.47430803058067816,-0.29373844618932715,5.1928477731586264,0.2857692407025649,2.4559635740626335,0.06298071889501843,1.027635769907882,2.9569963157150747,0.44303477605405855,0.12695555655645674,0.3803099800917596,-1.4935285643358234,-0.3925286203228279,0.19067127264620573,0.6607309570482511,0.25413257026133235,1.7692119702003737,0.5366787829519797	3643
Membrane invagination	7	17	2.4077704447173094	0.0160502695298723	P35579,Q06481,P84095,Q9Y5X1,P51790,Q14457,Q14185	Processes and pathways	GO Biological process	msigdb_gobp	280,39,139,107,459,189,94	1774,2963,1213,942,280,459,476,1723,1156,139,39,3348,94,189,3042,1925,107	-0.06576592628969985,-0.5921770650124923,0.15884550726049723,0.2857692407025649,1.027635769907882,0.6916031594494587,0.6607309570482511,-0.03347806686168351,0.19067127264620573,1.623176179314646,3.257840018273795,-0.931491220478586,2.0006717808585845,1.387215394486587,-0.6257295573052645,-0.098122333905974,1.943054324684516	3643
Regulation of immune effector process	19	54	2.402644880897961	0.0162769854421838	Q96FV9,P30511,P14174,Q01650,Q9NY93,Q9BY67,Q06481,P02786,Q7Z434,P04439,O96028,O15400,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1	Processes and pathways	GO Biological process	msigdb_gobp	681,138,15,143,429,304,39,409,420,590,87,586,338,227,102,476,638,235,522	586,2502,2860,2796,235,87,1872,409,2508,590,2509,1081,653,3256,338,1082,15,1084,1878,138,3520,2229,3297,1548,2712,476,143,39,1310,1395,1727,2526,2532,1404,2535,969,1737,420,2178,2377,1923,681,914,1928,3235,304,3479,522,638,2394,227,102,429,3098	0.5366787829519797,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,1.1482768495977804,2.11542427763213,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.3265940252928932,0.2224334357534765,0.47430803058067816,-0.8287924672030076,0.9061816816409076,0.2224334357534765,4.964849362308119,0.2224334357534765,-0.098122333905974,1.623176179314646,-1.315246174406957,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,-0.42560918711049844,0.6607309570482511,1.5938382520831849,3.257840018273795,0.12695555655645674,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,-0.19560956934146895,-0.2609563355332265,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.9973494401983068,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,1.9718833674139287,0.7531817696547146,-0.6593637349435877	3643
Proteasome, subunit alpha/beta [IPR001353]	6	14	2.4005582387551905	0.0163700856027475	P28070,P28074,P20618,P28072,Q99436,P49721	Sequence	InterPro Family	interpro_family	164,41,137,146,121,60	3142,137,2762,1461,1621,2802,3222,164,146,41,2878,60,283,121	-0.726880811724572,1.623176179314646,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.525313577596298,2.5402599154147643,1.027635769907882,1.7692119702003737	3643
Shoulder girdle muscle weakness	7	17	2.399970693940266	0.0163963844862384	P07602,Q8TD16,Q7LG56,P06753,Q9H9S5,Q96RR1,Q13049	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	69,272,464,394,347,319,188	1000,2136,394,69,2331,890,2432,2242,2349,188,477,464,272,319,347,1064,1604	0.25413257026133235,-0.19560956934146895,0.7838890695289682,2.427791890653298,-0.2609563355332265,0.31734400267200297,-0.29373844618932715,-0.22824695247054547,-0.2609563355332265,1.387215394486587,0.6607309570482511,0.6916031594494587,1.0578712931665288,0.9670119136618348,0.9061816816409076,0.25413257026133235,0.030894617027511038	3643
Developmental maturation	7	44	2.3939764072628167	0.0166668208252562	Q8N2A8,P22466,O94788,P07196,Q12834,O75503,P05067	Processes and pathways	GO Biological process	msigdb_gobp	68,38,9,125,284,24,29	2792,999,2860,1864,2796,24,296,9,703,3255,29,125,1080,2143,840,3436,3406,2925,38,1968,708,3035,2713,1301,459,2437,1396,801,284,2596,1166,1899,1245,718,3169,2607,68,1328,3427,1933,1064,1853,452,2496	-0.4920008457387619,0.25413257026133235,-0.525313577596298,-0.098122333905974,-0.4920008457387619,4.11230346222967,0.9973494401983068,5.816916168706705,0.44303477605405855,-0.8287924672030076,3.6353042018995785,1.7400910153055076,0.2224334357534765,-0.19560956934146895,0.34885740302862467,-1.104482929673742,-1.0350054838275398,-0.5587053640309138,3.257840018273795,-0.13054795621506413,0.44303477605405855,-0.6257295573052645,-0.42560918711049844,0.12695555655645674,0.6916031594494587,-0.29373844618932715,0.09500082791205905,0.3803099800917596,1.027635769907882,-0.3595238272390506,0.19067127264620573,-0.098122333905974,0.15884550726049723,0.44303477605405855,-0.726880811724572,-0.3595238272390506,2.4559635740626335,0.12695555655645674,-1.069696640684267,-0.098122333905974,0.25413257026133235,-0.06576592628969985,0.7224199472328477,-0.29373844618932715	3643
Dysostosis multiplex	6	8	2.393414520004096	0.0166923704069839	P16278,O00754,P04066,P15586,P54802,P10619	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,435,228,410,147,59	435,228,455,59,410,155,147,2180	0.7224199472328477,1.1783129469800828,0.6916031594494587,2.5402599154147643,0.7531817696547146,1.5350292358486646,1.5644560394229112,-0.19560956934146895	3643
Intrinsic component of organelle membrane	55	149	2.380306804021398	0.0172982290550285	Q86XL3,O15118,Q9P2E9,O96008,Q15629,P30511,Q8N2H4,Q99595,Q7L0J3,Q13505,Q99442,Q9HCU5,O75298,Q9Y5Z9,Q8TCT8,Q9HC21,Q9UBM7,O95563,Q8N4V1,P10321,Q9UH99,Q9NWR8,Q86UP2,Q8TB61,Q14739,Q15070,P42892,Q9BPX6,Q9BUB7,Q969N2,Q5H8A4,P50336,Q5SNT2,Q9Y282,Q16891,O60499,Q9H3K2,O43505,Q9Y2U8,Q9Y4W6,Q6P4A7,O43752,O75431,P61020,P04439,O95070,O95470,Q9Y2R0,Q9NX63,Q5T9L3,Q9H4I9,P57105,Q9NXW2,O75844,Q9GZY8	Localization	GO Cellular component	msigdb_gocc	513,252,407,500,509,138,672,682,17,19,547,687,393,291,158,553,289,152,167,532,170,305,301,573,416,417,53,320,447,318,569,313,442,193,568,196,734,205,744,608,719,454,213,596,590,700,701,219,494,767,244,238,782,248,130	1206,2751,1772,1954,252,1073,1695,2216,2858,205,454,2754,2504,196,2795,393,213,248,1285,881,2326,1698,3102,700,791,701,152,500,1872,590,3497,532,2331,2332,1015,2578,2658,1711,3030,138,3031,53,313,3264,2156,1887,2351,238,596,2807,1477,2812,1028,1159,2527,19,1484,416,962,1317,417,902,1649,509,2774,3501,568,905,3581,569,3474,442,767,1491,3045,719,1173,809,971,17,301,513,810,1176,3275,1177,2462,2007,672,167,2994,1498,1664,2949,573,158,3492,2012,1921,318,3231,1048,3634,2543,2906,2020,547,682,320,2688,1581,447,3056,3553,2114,130,734,244,1057,2118,553,687,1193,2392,1847,2844,1355,305,494,782,2488,2847,3007,407,289,2400,3062,170,1593,2959,193,219,744,874,1603,608,786,291,995	0.15884550726049723,-0.4587663248239629,-0.06576592628969985,-0.13054795621506413,1.08805639508316,0.2224334357534765,-0.03347806686168351,-0.22824695247054547,-0.525313577596298,1.2979715997804608,0.6916031594494587,-0.4587663248239629,-0.3265940252928932,1.3575144142492008,-0.4920008457387619,0.7838890695289682,1.2382387072449188,1.118191455601226,0.12695555655645674,0.31734400267200297,-0.2609563355332265,-0.03347806686168351,-0.6930805097254553,0.44303477605405855,0.3803099800917596,0.44303477605405855,1.5350292358486646,0.6298028841948623,-0.098122333905974,0.5366787829519797,-1.244601121096576,0.5988184783374502,-0.2609563355332265,-0.2609563355332265,0.25413257026133235,-0.3595238272390506,-0.3925286203228279,-0.03347806686168351,-0.6257295573052645,1.623176179314646,-0.6257295573052645,2.763483088965262,0.9670119136618348,-0.8287924672030076,-0.19560956934146895,-0.098122333905974,-0.2609563355332265,1.1482768495977804,0.5366787829519797,-0.4920008457387619,0.06298071889501843,-0.4920008457387619,0.25413257026133235,0.19067127264620573,-0.3265940252928932,4.451389856938803,0.06298071889501843,0.7531817696547146,0.2857692407025649,0.12695555655645674,0.7531817696547146,0.31734400267200297,-0.0012581004565036626,0.6298028841948623,-0.4587663248239629,-1.244601121096576,0.5677772700633923,0.31734400267200297,-1.63783022894056,0.5677772700633923,-1.174345720866778,0.7224199472328477,0.4117022638315761,0.06298071889501843,-0.6257295573052645,0.44303477605405855,0.19067127264620573,0.3803099800917596,0.2857692407025649,4.734981990697083,0.9973494401983068,0.6298028841948623,0.3803099800917596,0.19067127264620573,-0.8287924672030076,0.19067127264620573,-0.29373844618932715,-0.13054795621506413,0.47430803058067816,1.5055575321040489,-0.5921770650124923,0.06298071889501843,-0.0012581004565036626,-0.5587053640309138,0.5677772700633923,1.5350292358486646,-1.209424370050621,-0.13054795621506413,-0.098122333905974,0.9670119136618348,-0.7947358122572576,0.25413257026133235,-4.5798467158688725,-0.3265940252928932,-0.525313577596298,-0.13054795621506413,0.5988184783374502,0.47430803058067816,0.9670119136618348,-0.3925286203228279,0.030894617027511038,0.7224199472328477,-0.6257295573052645,-1.4576838354723742,-0.16304347134508207,1.7109272480905777,0.44303477605405855,1.1482768495977804,0.25413257026133235,-0.16304347134508207,0.5988184783374502,0.47430803058067816,0.19067127264620573,-0.2609563355332265,-0.06576592628969985,-0.4920008457387619,0.12695555655645674,0.9973494401983068,0.6607309570482511,0.4117022638315761,-0.29373844618932715,-0.4920008457387619,-0.5921770650124923,0.7838890695289682,1.027635769907882,-0.2609563355332265,-0.6257295573052645,1.5055575321040489,0.030894617027511038,-0.5587053640309138,1.387215394486587,1.2382387072449188,0.44303477605405855,0.34885740302862467,0.030894617027511038,0.5366787829519797,0.4117022638315761,1.027635769907882,0.2857692407025649	3643
serine protease	7	19	2.3768624652921644	0.0174605971147387	Q9H3G5,Q9HB40,P42785,Q4J6C6,Q16740,O14773,P10619	Functions	Panther Protein class	panther_protein_class	359,35,4,135,113,391,59	391,59,3220,3109,2659,1973,4,3201,2254,113,1652,135,2005,2989,859,491,359,35,3464	0.7838890695289682,2.5402599154147643,-0.7947358122572576,-0.6930805097254553,-0.3925286203228279,-0.13054795621506413,6.233993929662534,-0.7607655898218467,-0.22824695247054547,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,-0.13054795621506413,-0.5921770650124923,0.34885740302862467,0.6607309570482511,0.8756881681175116,3.447308651903207,-1.1393655482262741	3643
Regulation of b cell activation	6	19	2.3754919673793244	0.0175255738522943	P02786,Q9NQT5,P14174,Q9NPF0,P00813,O96028	Processes and pathways	GO Biological process	msigdb_gobp	409,638,15,492,56,87	2410,87,56,409,15,1548,2526,1404,1100,2535,969,1737,681,914,1339,1928,492,638,2788	-0.29373844618932715,2.11542427763213,2.6800374279695216,0.7531817696547146,4.964849362308119,0.030894617027511038,-0.3265940252928932,0.09500082791205905,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.098122333905974,0.6607309570482511,0.5055225334229401,-0.4587663248239629	3643
Tetrapyrrole metabolic process	6	24	2.3742587220640834	0.0175842244010386	P22830,Q9NUN5,P30519,O14678,O75027,Q7KZN9	Processes and pathways	GO Biological process	msigdb_gobp	0,123,14,176,21,286	932,176,21,3366,2142,653,0,14,3615,2342,1544,313,2157,3502,286,1337,820,1193,492,2844,123,2786,3243,3246	0.2857692407025649,1.446478167816503,4.373525061543824,-0.9659039071751861,-0.19560956934146895,0.47430803058067816,9.72862962082004,5.1928477731586264,-2.2291720974867153,-0.2609563355332265,0.030894617027511038,0.9670119136618348,-0.19560956934146895,-1.244601121096576,1.027635769907882,0.12695555655645674,0.3803099800917596,0.19067127264620573,0.6607309570482511,-0.4920008457387619,1.7692119702003737,-0.4587663248239629,-0.7947358122572576,-0.7947358122572576	3643
Rho gtpase cycle	42	172	2.3677562608438825	0.0178963215645293	P78371,P84095,Q86VI3,P30519,Q96N67,P06753,Q13505,Q9Y5S2,Q9UQB8,Q92888,Q96JJ3,Q86UP2,P02786,Q07960,Q07065,Q14739,O75116,Q9BXS4,P67936,Q13813,P20700,P12814,Q9NZM3,O15173,Q96RU3,Q13464,O75976,P61201,Q96F07,Q7L576,P41440,P11274,Q14185,Q8NBN3,Q9Y6M7,P08670,Q01082,Q9BT78,O75955,Q96HY6,Q96DH6,Q9UEY8	Processes and pathways	Reactome Pathways	msigdb_reactome	378,139,140,14,401,394,19,162,26,424,302,301,409,298,173,416,293,50,181,315,310,308,336,199,204,328,206,461,344,340,90,338,94,225,361,104,365,385,249,384,517,526	645,3141,1774,199,2213,1136,789,1534,293,1368,3145,249,206,1372,1782,1786,409,3218,394,1789,1142,1457,104,2800,338,2707,308,3468,3552,3629,310,563,1622,14,1382,1542,1150,2876,1547,90,793,2344,709,1153,794,849,2156,1887,2583,2240,2349,1723,461,3489,1389,2250,1156,3120,181,378,3622,139,952,365,2257,800,2259,1310,173,298,2438,3411,3444,1643,2940,2261,1644,1479,3121,328,2596,19,2528,2170,315,2263,1033,3225,2267,94,1315,1095,416,662,965,1404,855,856,1567,2603,3043,1821,1824,2095,3567,2001,340,1325,301,140,513,1661,2372,2373,1045,723,2463,225,973,974,1330,2099,3308,424,1834,2378,1049,3415,1835,517,344,384,302,2288,401,863,204,2736,820,1342,2688,385,1266,685,1347,50,1424,2389,1844,2119,3568,2556,988,783,336,3007,1944,2037,526,3062,1360,1595,2564,26,2129,3140,3585,744,786,162,361,583	0.47430803058067816,-0.726880811724572,-0.06576592628969985,1.327766595224347,-0.22824695247054547,0.19067127264620573,0.3803099800917596,0.030894617027511038,0.9973494401983068,0.09500082791205905,-0.726880811724572,1.118191455601226,1.2979715997804608,0.09500082791205905,-0.06576592628969985,-0.06576592628969985,0.7531817696547146,-0.7947358122572576,0.7838890695289682,-0.06576592628969985,0.19067127264620573,0.06298071889501843,1.943054324684516,-0.4920008457387619,0.9061816816409076,-0.42560918711049844,0.9670119136618348,-1.174345720866778,-1.4576838354723742,-2.997816021189173,0.9670119136618348,0.5677772700633923,-0.0012581004565036626,5.1928477731586264,0.09500082791205905,0.030894617027511038,0.19067127264620573,-0.525313577596298,0.030894617027511038,2.058127752852981,0.3803099800917596,-0.2609563355332265,0.44303477605405855,0.19067127264620573,0.3803099800917596,0.34885740302862467,-0.19560956934146895,-0.098122333905974,-0.3595238272390506,-0.22824695247054547,-0.2609563355332265,-0.03347806686168351,0.6916031594494587,-1.209424370050621,0.09500082791205905,-0.22824695247054547,0.19067127264620573,-0.6930805097254553,1.4168698692908286,0.8145422833591529,-2.6866252431254933,1.623176179314646,0.2857692407025649,0.845141841466991,-0.22824695247054547,0.3803099800917596,-0.22824695247054547,0.12695555655645674,1.4760406150941263,0.9973494401983068,-0.29373844618932715,-1.0350054838275398,-1.104482929673742,-0.0012581004565036626,-0.5587053640309138,-0.22824695247054547,-0.0012581004565036626,0.06298071889501843,-0.6930805097254553,0.9366227945511973,-0.3595238272390506,4.451389856938803,-0.3265940252928932,-0.19560956934146895,0.9670119136618348,-0.22824695247054547,0.25413257026133235,-0.7947358122572576,-0.22824695247054547,2.0006717808585845,0.12695555655645674,0.2224334357534765,0.7531817696547146,0.47430803058067816,0.2857692407025649,0.09500082791205905,0.34885740302862467,0.34885740302862467,0.030894617027511038,-0.3595238272390506,-0.6257295573052645,-0.06576592628969985,-0.06576592628969985,-0.16304347134508207,-1.5294661704120023,-0.13054795621506413,0.9061816816409076,0.12695555655645674,0.9973494401983068,1.623176179314646,0.6298028841948623,-0.0012581004565036626,-0.2609563355332265,-0.2609563355332265,0.25413257026133235,0.44303477605405855,-0.29373844618932715,1.2083001127798034,0.2857692407025649,0.2857692407025649,0.12695555655645674,-0.16304347134508207,-0.8629365633590367,0.7531817696547146,-0.06576592628969985,-0.2609563355332265,0.25413257026133235,-1.0350054838275398,-0.06576592628969985,0.6298028841948623,0.9061816816409076,0.8145422833591529,0.9973494401983068,-0.22824695247054547,0.7838890695289682,0.34885740302862467,1.327766595224347,-0.42560918711049844,0.3803099800917596,0.12695555655645674,-0.3925286203228279,0.8145422833591529,0.15884550726049723,0.47430803058067816,0.12695555655645674,2.901874777421383,0.09500082791205905,-0.2609563355332265,-0.06576592628969985,-0.16304347134508207,-1.5294661704120023,-0.3265940252928932,0.2857692407025649,0.4117022638315761,0.9366227945511973,-0.5921770650124923,-0.098122333905974,-0.13054795621506413,0.6298028841948623,-0.6257295573052645,0.12695555655645674,0.030894617027511038,-0.3265940252928932,3.9014137223503935,-0.16304347134508207,-0.6930805097254553,-1.6741333670170677,0.44303477605405855,0.4117022638315761,1.5350292358486646,0.8756881681175116,0.5677772700633923	3643
Apical part of cell	17	70	2.364597730278956	0.0180496643677661	P11166,P55011,P26038,Q99538,P53985,O75787,Q01650,P51790,Q9Y4G8,O14523,P30825,O43865,P78536,O75955,P41440,P05067,Q9Y6M7	Localization	GO Cellular component	msigdb_gocc	279,440,501,520,44,296,143,459,81,453,54,55,216,249,90,29,361	1770,1207,453,1444,2793,2571,1003,1004,55,1367,296,249,3617,2508,1962,2054,3149,29,1374,704,2923,1457,279,3321,941,843,1015,2061,3422,1294,2517,501,54,2342,708,2068,1624,1544,2661,2151,90,459,44,3075,440,1723,2587,216,143,1029,715,2443,2086,1315,963,1243,1650,541,2460,1500,520,2737,2292,1354,2695,2912,1520,81,3315,361	-0.06576592628969985,0.15884550726049723,0.6916031594494587,0.06298071889501843,-0.4920008457387619,-0.3595238272390506,0.25413257026133235,0.25413257026133235,2.6800374279695216,0.09500082791205905,0.9973494401983068,1.118191455601226,-2.342454069604444,-0.3265940252928932,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,3.6353042018995785,0.09500082791205905,0.44303477605405855,-0.5587053640309138,0.06298071889501843,1.027635769907882,-0.8971691305719629,0.2857692407025649,0.34885740302862467,0.25413257026133235,-0.16304347134508207,-1.069696640684267,0.12695555655645674,-0.3265940252928932,0.6298028841948623,2.707887319665007,-0.2609563355332265,0.44303477605405855,-0.16304347134508207,-0.0012581004565036626,0.030894617027511038,-0.3925286203228279,-0.19560956934146895,2.058127752852981,0.6916031594494587,3.1215736355280526,-0.6593637349435877,0.7224199472328477,-0.03347806686168351,-0.3595238272390506,1.2382387072449188,1.5938382520831849,0.25413257026133235,0.44303477605405855,-0.29373844618932715,-0.16304347134508207,0.12695555655645674,0.2857692407025649,0.15884550726049723,-0.0012581004565036626,0.5988184783374502,-0.29373844618932715,0.06298071889501843,0.6298028841948623,-0.42560918711049844,-0.22824695247054547,0.12695555655645674,-0.3925286203228279,-0.525313577596298,0.06298071889501843,2.2579809707838456,-0.8629365633590367,0.8756881681175116	3643
Visual loss	20	58	2.3625383940890603	0.0181502612672996	O14773,O75503,A2RRP1,O60313,Q96JJ3,Q8NHS3,P00403,P03886,P07602,Q15046,P50897,O15078,P00846,P52732,P51798,P04439,Q15051,O75306,Q01082,Q9NWW5	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	391,24,528,529,302,52,559,62,69,566,72,194,74,326,460,590,223,471,365,251	528,2210,1281,1605,391,194,1956,529,471,2137,24,748,791,2705,559,3148,74,1872,62,2967,3450,590,69,1874,1792,1707,2338,2580,592,708,3296,1019,2232,3453,72,2238,460,326,948,2242,3471,365,658,897,1728,566,223,3393,52,3276,813,2286,302,3176,3178,251,2399,1064	0.5988184783374502,-0.22824695247054547,0.12695555655645674,-0.0012581004565036626,0.7838890695289682,1.3575144142492008,-0.13054795621506413,0.5988184783374502,0.6607309570482511,-0.19560956934146895,4.11230346222967,0.4117022638315761,0.3803099800917596,-0.42560918711049844,0.5677772700633923,-0.726880811724572,2.371337868662573,-0.098122333905974,2.512197372488192,-0.5921770650124923,-1.1393655482262741,0.5366787829519797,2.427791890653298,-0.098122333905974,-0.06576592628969985,-0.03347806686168351,-0.2609563355332265,-0.3595238272390506,0.5366787829519797,0.44303477605405855,-0.8629365633590367,0.25413257026133235,-0.22824695247054547,-1.1393655482262741,2.399583395405736,-0.22824695247054547,0.6916031594494587,0.9366227945511973,0.2857692407025649,-0.22824695247054547,-1.174345720866778,0.845141841466991,0.47430803058067816,0.31734400267200297,-0.03347806686168351,0.5677772700633923,1.2083001127798034,-1.0004082879139022,2.818941470146897,-0.8287924672030076,0.3803099800917596,-0.22824695247054547,0.9973494401983068,-0.726880811724572,-0.726880811724572,1.118191455601226,-0.2609563355332265,0.25413257026133235	3643
Abnormal pyramidal sign	30	130	2.361903316726929	0.0181813831707116	Q99720,O75298,O75027,O14773,Q9NR77,P11166,O60313,Q8N0X7,O75787,O95831,O75251,Q9H6K4,Q969N2,Q6DKK2,P20700,O00754,P07602,Q15046,P00846,Q7LG56,Q9Y4W6,Q9H9S5,P41440,P04066,O75569,Q9NZ08,O75306,O43681,P07196,Q9UEY8	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,393,21,391,32,279,529,421,296,47,294,579,318,190,310,435,69,566,74,464,608,347,90,228,350,245,471,118,125,526	2321,646,1605,2408,1862,435,391,1210,3251,118,529,1865,2920,21,294,393,471,3144,350,296,3363,2417,791,47,74,1872,228,125,3151,69,1874,1963,2655,3256,279,1876,2424,591,2869,2925,1222,310,1796,2228,3028,2971,753,1462,1542,1971,754,2431,3033,2232,1975,90,1548,1467,2236,1718,3036,1887,1301,2520,2583,3626,1553,710,1387,2349,2880,797,1808,3471,801,2082,1992,1238,963,566,964,3204,3502,668,2452,190,2729,1407,464,2895,3393,421,859,2176,2538,2098,1918,2011,2012,813,3173,2378,318,2381,1050,2289,2,2112,2193,1755,579,2118,347,32,2556,1849,245,1064,2785,1521,3519,526,1274,2562,1690,1203,1692,608,1068,693	-0.2609563355332265,0.47430803058067816,-0.0012581004565036626,-0.29373844618932715,-0.098122333905974,0.7224199472328477,0.7838890695289682,0.15884550726049723,-0.8287924672030076,1.7982903969638317,0.5988184783374502,-0.098122333905974,-0.5587053640309138,4.373525061543824,0.9973494401983068,0.7838890695289682,0.6607309570482511,-0.726880811724572,0.8756881681175116,0.9973494401983068,-0.9659039071751861,-0.29373844618932715,0.3803099800917596,3.0119856905575273,2.371337868662573,-0.098122333905974,1.1783129469800828,1.7400910153055076,-0.726880811724572,2.427791890653298,-0.098122333905974,-0.13054795621506413,-0.3925286203228279,-0.8287924672030076,1.027635769907882,-0.098122333905974,-0.29373844618932715,0.5366787829519797,-0.525313577596298,-0.5587053640309138,0.15884550726049723,0.9670119136618348,-0.06576592628969985,-0.22824695247054547,-0.6257295573052645,-0.5921770650124923,0.4117022638315761,0.06298071889501843,0.030894617027511038,-0.13054795621506413,0.4117022638315761,-0.29373844618932715,-0.6257295573052645,-0.22824695247054547,-0.13054795621506413,2.058127752852981,0.030894617027511038,0.06298071889501843,-0.22824695247054547,-0.03347806686168351,-0.6257295573052645,-0.098122333905974,0.12695555655645674,-0.3265940252928932,-0.3595238272390506,-2.919565762049335,0.030894617027511038,0.44303477605405855,0.09500082791205905,-0.2609563355332265,-0.525313577596298,0.3803099800917596,-0.06576592628969985,-1.174345720866778,0.3803099800917596,-0.16304347134508207,-0.13054795621506413,0.15884550726049723,0.2857692407025649,0.5677772700633923,0.2857692407025649,-0.7607655898218467,-1.244601121096576,0.47430803058067816,-0.29373844618932715,1.387215394486587,-0.42560918711049844,0.09500082791205905,0.6916031594494587,-0.525313577596298,-1.0004082879139022,0.7531817696547146,0.34885740302862467,-0.19560956934146895,-0.3265940252928932,-0.16304347134508207,-0.098122333905974,-0.13054795621506413,-0.13054795621506413,0.3803099800917596,-0.726880811724572,-0.2609563355332265,0.9670119136618348,-0.2609563355332265,0.25413257026133235,-0.22824695247054547,8.21990109917503,-0.16304347134508207,-0.19560956934146895,-0.03347806686168351,0.5677772700633923,-0.16304347134508207,0.9061816816409076,3.6085359292973544,-0.3265940252928932,-0.06576592628969985,1.1482768495977804,0.25413257026133235,-0.4587663248239629,0.06298071889501843,-1.2798752825252815,0.6298028841948623,0.15884550726049723,-0.3265940252928932,-0.0012581004565036626,0.19067127264620573,-0.0012581004565036626,0.5366787829519797,0.25413257026133235,0.47430803058067816	3643
Paresthesia	6	30	2.357576015954117	0.0183946887567525	Q9NR77,Q9NZ08,P07196,P06280,P54802,P05067	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,245,125,153,147,29	1281,1956,791,1872,1288,29,3366,153,125,2142,279,1148,2658,2580,1548,2236,1553,2242,710,147,2349,1808,3204,464,2176,2622,579,32,245,2490	0.12695555655645674,-0.13054795621506413,0.3803099800917596,-0.098122333905974,0.12695555655645674,3.6353042018995785,-0.9659039071751861,1.5350292358486646,1.7400910153055076,-0.19560956934146895,1.027635769907882,0.19067127264620573,-0.3925286203228279,-0.3595238272390506,0.030894617027511038,-0.22824695247054547,0.030894617027511038,-0.22824695247054547,0.44303477605405855,1.5644560394229112,-0.2609563355332265,-0.06576592628969985,-0.7607655898218467,0.6916031594494587,-0.19560956934146895,-0.3595238272390506,0.5677772700633923,3.6085359292973544,1.1482768495977804,-0.29373844618932715	3643
metalloprotease	8	27	2.3561426244973567	0.0184658262602459	P22695,P52888,Q9UIQ6,Q9NZ08,P42892,Q9NQH7,O75844,P55786	Functions	Panther Protein class	panther_protein_class	311,98,42,245,53,386,248,31	1137,2137,248,885,409,3108,2760,311,3323,1713,53,98,1554,31,658,1042,2776,1322,1188,1264,2737,1422,386,3137,245,42,608	0.19067127264620573,-0.19560956934146895,1.118191455601226,0.31734400267200297,0.7531817696547146,-0.6930805097254553,-0.4587663248239629,0.9670119136618348,-0.8971691305719629,-0.03347806686168351,2.763483088965262,1.9718833674139287,0.030894617027511038,3.6085359292973544,0.47430803058067816,0.25413257026133235,-0.4587663248239629,0.12695555655645674,0.19067127264620573,0.15884550726049723,-0.42560918711049844,0.09500082791205905,0.8145422833591529,-0.6930805097254553,1.1482768495977804,3.2306497156014906,0.5366787829519797	3643
Dementia	17	60	2.3552571525257315	0.0185098913836803	P03886,P20700,O60313,Q14108,P07602,P27544,O15118,P61916,O96008,Q9Y487,P00846,Q7LG56,Q14203,O43681,Q9NWW5,Q96RR1,P05067	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	62,310,529,255,69,502,252,351,500,43,74,464,415,118,251,319,29	1605,252,118,529,1078,881,500,2705,559,74,62,2967,703,2758,2654,29,1013,69,1376,2655,2869,310,1796,944,2228,502,753,754,1624,2661,890,1301,2242,1387,2349,351,2721,955,1992,3473,255,415,665,1827,464,3393,2608,2012,3091,2624,1675,319,3177,2482,251,1064,1521,3519,1690,43	-0.0012581004565036626,1.08805639508316,1.7982903969638317,0.5988184783374502,0.2224334357534765,0.31734400267200297,0.6298028841948623,-0.42560918711049844,0.5677772700633923,2.371337868662573,2.512197372488192,-0.5921770650124923,0.44303477605405855,-0.4587663248239629,-0.3925286203228279,3.6353042018995785,0.25413257026133235,2.427791890653298,0.09500082791205905,-0.3925286203228279,-0.525313577596298,0.9670119136618348,-0.06576592628969985,0.2857692407025649,-0.22824695247054547,0.6298028841948623,0.4117022638315761,0.4117022638315761,-0.0012581004565036626,-0.3925286203228279,0.31734400267200297,0.12695555655645674,-0.22824695247054547,0.09500082791205905,-0.2609563355332265,0.8756881681175116,-0.42560918711049844,0.2857692407025649,-0.13054795621506413,-1.174345720866778,1.08805639508316,0.7531817696547146,0.47430803058067816,-0.06576592628969985,0.6916031594494587,-1.0004082879139022,-0.3595238272390506,-0.13054795621506413,-0.6593637349435877,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,-0.726880811724572,-0.29373844618932715,1.118191455601226,0.25413257026133235,0.06298071889501843,-1.2798752825252815,-0.0012581004565036626,3.2306497156014906	3643
Cell activation	34	149	2.3550154867086595	0.0185219337500999	Q92538,P46379,P26038,Q9HCL2,P30511,P14174,Q9Y6D9,P05067,P35579,Q9UQ84,P22466,Q9BY67,P02786,P80404,Q96L92,P30825,P00813,Q92542,P24390,P23396,P12814,Q15046,Q8WXW3,P12956,P04439,O96028,P78536,Q9NPF0,P11274,Q9NRA0,P31749,Q9NUQ9,P51809,O95219	Processes and pathways	GO Biological process	msigdb_gobp	515,3,501,5,138,15,555,29,280,33,38,304,409,413,575,54,56,317,562,437,308,566,468,83,590,87,216,492,338,227,592,102,476,235	1207,1952,3065,2792,2323,2410,2501,2215,2860,1217,235,2702,3365,87,2757,3147,56,3617,409,703,2508,590,1288,29,1873,3218,1081,653,1144,1377,3256,1704,338,1082,3193,3591,308,83,3513,15,3629,1083,1084,1620,2337,38,437,562,1148,501,138,54,592,2874,708,2229,1018,280,3200,1151,1296,1547,1086,1548,3,3155,2582,3440,3344,476,1386,1553,1554,1632,1889,3268,1233,2436,2162,1559,1390,216,3038,413,1988,2080,2720,800,1893,2938,1815,3270,1395,1727,2526,1994,2267,1315,1095,566,3621,2532,1038,1404,1097,3501,1489,1100,2535,969,3305,1737,1177,468,515,317,2015,2377,978,2619,681,914,1339,2621,980,575,1928,3235,2114,304,3211,3479,5,492,638,227,871,102,1852,3098,2308,2788,3010,1855,33,2206,1858,1951,555	0.15884550726049723,-0.13054795621506413,-0.6593637349435877,-0.4920008457387619,-0.2609563355332265,-0.29373844618932715,-0.3265940252928932,-0.22824695247054547,-0.525313577596298,0.15884550726049723,1.1482768495977804,-0.42560918711049844,-0.9659039071751861,2.11542427763213,-0.4587663248239629,-0.726880811724572,2.6800374279695216,-2.342454069604444,0.7531817696547146,0.44303477605405855,-0.3265940252928932,0.5366787829519797,0.12695555655645674,3.6353042018995785,-0.098122333905974,-0.7947358122572576,0.2224334357534765,0.47430803058067816,0.19067127264620573,0.09500082791205905,-0.8287924672030076,-0.03347806686168351,0.9061816816409076,0.2224334357534765,-0.7607655898218467,-1.7470088834303552,0.9670119136618348,2.172563346869744,-1.2798752825252815,4.964849362308119,-2.997816021189173,0.2224334357534765,0.2224334357534765,-0.0012581004565036626,-0.2609563355332265,3.257840018273795,0.7224199472328477,0.5677772700633923,0.19067127264620573,0.6298028841948623,1.623176179314646,2.707887319665007,0.5366787829519797,-0.525313577596298,0.44303477605405855,-0.22824695247054547,0.25413257026133235,1.027635769907882,-0.7607655898218467,0.19067127264620573,0.12695555655645674,0.030894617027511038,0.2224334357534765,0.030894617027511038,7.00443820279511,-0.726880811724572,-0.3595238272390506,-1.104482929673742,-0.931491220478586,0.6607309570482511,0.09500082791205905,0.030894617027511038,0.030894617027511038,-0.0012581004565036626,-0.098122333905974,-0.8287924672030076,0.15884550726049723,-0.29373844618932715,-0.19560956934146895,0.030894617027511038,0.09500082791205905,1.2382387072449188,-0.6257295573052645,0.7531817696547146,-0.13054795621506413,-0.16304347134508207,-0.42560918711049844,0.3803099800917596,-0.098122333905974,-0.5587053640309138,-0.06576592628969985,-0.8287924672030076,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.13054795621506413,-0.22824695247054547,0.12695555655645674,0.2224334357534765,0.5677772700633923,-2.4183808791889665,-0.3265940252928932,0.25413257026133235,0.09500082791205905,0.2224334357534765,-1.244601121096576,0.06298071889501843,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.8629365633590367,-0.03347806686168351,0.19067127264620573,0.6916031594494587,0.6298028841948623,0.9670119136618348,-0.13054795621506413,-0.2609563355332265,0.2857692407025649,-0.3595238272390506,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.3595238272390506,0.2857692407025649,0.5677772700633923,-0.098122333905974,-0.7947358122572576,-0.16304347134508207,0.9973494401983068,-0.7607655898218467,-1.174345720866778,6.233993929662534,0.6607309570482511,0.5055225334229401,1.2083001127798034,0.34885740302862467,1.9718833674139287,-0.06576592628969985,-0.6593637349435877,-0.22824695247054547,-0.4587663248239629,-0.5921770650124923,-0.06576592628969985,3.6085359292973544,-0.19560956934146895,-0.06576592628969985,-0.098122333905974,0.5988184783374502	3643
Glycerophospholipid biosynthesis	6	35	2.349120570198709	0.0188178122374707	Q8N2A8,Q9HCL2,Q8IV08,Q9NPH0,P35790,Q8NCC3	Processes and pathways	Reactome Pathways	msigdb_reactome	68,5,73,111,51,28	3510,584,2700,2221,2651,1147,51,2232,891,3557,2934,2880,1025,3165,905,2607,73,68,3394,28,1916,602,603,358,3179,3053,2838,984,1191,5,111,2482,1196,2400,185	-1.2798752825252815,0.5366787829519797,-0.42560918711049844,-0.22824695247054547,-0.3925286203228279,0.19067127264620573,2.8742639930235563,-0.22824695247054547,0.31734400267200297,-1.4935285643358234,-0.5587053640309138,-0.525313577596298,0.25413257026133235,-0.726880811724572,0.31734400267200297,-0.3595238272390506,2.399583395405736,2.4559635740626335,-1.0004082879139022,3.768713037747525,-0.098122333905974,0.5366787829519797,0.5366787829519797,0.8756881681175116,-0.726880811724572,-0.6257295573052645,-0.4920008457387619,0.2857692407025649,0.19067127264620573,6.233993929662534,1.914184390727662,-0.29373844618932715,0.19067127264620573,-0.2609563355332265,1.4168698692908286	3643
Heterogeneous	17	46	2.345634883694262	0.0189947043700438	Q9NR77,P11717,P03886,Q9Y3D3,Q15555,O15344,Q15051,P61916,P00846,Q9NWH9,Q14203,P02545,P06753,P07196,O75844,P05067,P29372	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,154,62,198,355,253,223,351,74,371,415,265,394,125,248,29,438	253,531,248,2651,74,1872,265,62,2967,1288,29,394,125,154,2331,3552,2515,438,592,708,2229,2764,2232,2933,1155,1301,460,1632,2242,2716,351,1033,415,223,355,1566,2942,3226,2997,3630,3561,2783,32,371,198,693	1.08805639508316,0.5988184783374502,1.118191455601226,-0.3925286203228279,2.371337868662573,-0.098122333905974,1.0578712931665288,2.512197372488192,-0.5921770650124923,0.12695555655645674,3.6353042018995785,0.7838890695289682,1.7400910153055076,1.5350292358486646,-0.2609563355332265,-1.4576838354723742,-0.3265940252928932,0.7224199472328477,0.5366787829519797,0.44303477605405855,-0.22824695247054547,-0.4587663248239629,-0.22824695247054547,-0.5587053640309138,0.19067127264620573,0.12695555655645674,0.6916031594494587,-0.0012581004565036626,-0.22824695247054547,-0.42560918711049844,0.8756881681175116,0.25413257026133235,0.7531817696547146,1.2083001127798034,0.8756881681175116,0.030894617027511038,-0.5587053640309138,-0.7947358122572576,-0.5921770650124923,-3.1552041982193537,-1.4935285643358234,-0.4587663248239629,3.6085359292973544,0.845141841466991,1.3575144142492008,0.47430803058067816	3643
Regulation of production of molecular mediator of immune response	12	31	2.344263638293548	0.0190646900143027	Q96FV9,P02786,Q7Z434,P30511,Q9NQT5,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0	Processes and pathways	GO Biological process	msigdb_gobp	681,409,420,138,638,15,143,590,87,429,522,227	2502,87,409,590,2509,653,15,1878,138,2229,1548,143,1727,2526,1404,2535,969,1737,420,2178,1923,681,914,1928,3235,3479,522,638,2394,227,429	-0.3265940252928932,2.11542427763213,0.7531817696547146,0.5366787829519797,-0.3265940252928932,0.47430803058067816,4.964849362308119,-0.098122333905974,1.623176179314646,-0.22824695247054547,0.030894617027511038,1.5938382520831849,-0.03347806686168351,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,-0.19560956934146895,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,0.7531817696547146	3643
Pdz domain binding	6	17	2.342349186339842	0.019162776886481	Q9BY67,P51790,Q9Y4G8,Q9UBI6,P78536,Q9UQB8	Functions	GO Molecular function	msigdb_gomf	304,459,81,451,216,26	2793,1015,2517,1628,459,2162,216,964,1166,572,2614,304,451,1360,26,81,1951	-0.4920008457387619,0.25413257026133235,-0.3265940252928932,-0.0012581004565036626,0.6916031594494587,-0.19560956934146895,1.2382387072449188,0.2857692407025649,0.19067127264620573,0.5677772700633923,-0.3595238272390506,0.9973494401983068,0.7224199472328477,0.12695555655645674,3.9014137223503935,2.2579809707838456,-0.098122333905974	3643
Ventricular arrhythmia	13	42	2.3416491880969423	0.0191987512466562	P03886,P49748,P23786,P00846,O43772,Q7LG56,P02545,P10253,P42892,P09493,Q96RR1,Q8NFF5,P50336	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	62,412,200,74,13,464,265,266,53,215,319,382,313	13,471,1454,2705,559,74,265,62,2967,1289,2142,215,3572,266,2331,2332,3468,3552,843,1796,200,1544,3115,1546,53,2432,412,313,849,2242,2256,2259,959,1033,464,382,976,3331,2180,319,1581,2399	5.243267115697605,0.6607309570482511,0.06298071889501843,-0.42560918711049844,0.5677772700633923,2.371337868662573,1.0578712931665288,2.512197372488192,-0.5921770650124923,0.12695555655645674,-0.19560956934146895,1.2382387072449188,-1.6016175956969314,1.0578712931665288,-0.2609563355332265,-0.2609563355332265,-1.174345720866778,-1.4576838354723742,0.34885740302862467,-0.06576592628969985,1.327766595224347,0.030894617027511038,-0.6930805097254553,0.030894617027511038,2.763483088965262,-0.29373844618932715,0.7531817696547146,0.9670119136618348,0.34885740302862467,-0.22824695247054547,-0.22824695247054547,-0.22824695247054547,0.2857692407025649,0.25413257026133235,0.6916031594494587,0.8145422833591529,0.2857692407025649,-0.8971691305719629,-0.19560956934146895,0.9670119136618348,0.030894617027511038,-0.2609563355332265	3643
Lymphocyte activation	26	110	2.3365339468617727	0.019463430487576	P46379,P26038,Q9HCL2,P30511,P14174,Q9Y6D9,P35579,Q9UQ84,P22466,Q9BY67,P02786,Q96L92,P30825,P00813,Q92542,P24390,P23396,Q8WXW3,P12956,P04439,O96028,P78536,Q9NPF0,P31749,Q9NUQ9,P51809	Processes and pathways	GO Biological process	msigdb_gobp	3,501,5,138,15,555,280,33,38,304,409,575,54,56,317,562,437,468,83,590,87,216,492,592,102,476	1952,2792,2410,2215,2860,1217,2702,3365,87,2757,3147,56,409,703,2508,590,1288,1873,3218,1081,1144,1377,3256,1082,3193,83,3513,15,3629,1083,1084,38,437,562,1148,501,138,54,592,2874,708,2229,1018,280,3200,1151,1296,1547,1086,1548,3,3440,3344,476,1553,1889,1233,2436,2162,1559,1390,216,3038,1988,2080,2720,1893,2938,1815,3270,1395,2526,2267,1315,1038,1404,3501,1489,1100,2535,969,3305,1737,1177,468,317,2015,978,2619,681,914,1339,2621,575,1928,3235,304,3479,5,492,638,871,102,1852,2308,2788,3010,33,1858,555	-0.13054795621506413,-0.4920008457387619,-0.29373844618932715,-0.22824695247054547,-0.525313577596298,0.15884550726049723,-0.42560918711049844,-0.9659039071751861,2.11542427763213,-0.4587663248239629,-0.726880811724572,2.6800374279695216,0.7531817696547146,0.44303477605405855,-0.3265940252928932,0.5366787829519797,0.12695555655645674,-0.098122333905974,-0.7947358122572576,0.2224334357534765,0.19067127264620573,0.09500082791205905,-0.8287924672030076,0.2224334357534765,-0.7607655898218467,2.172563346869744,-1.2798752825252815,4.964849362308119,-2.997816021189173,0.2224334357534765,0.2224334357534765,3.257840018273795,0.7224199472328477,0.5677772700633923,0.19067127264620573,0.6298028841948623,1.623176179314646,2.707887319665007,0.5366787829519797,-0.525313577596298,0.44303477605405855,-0.22824695247054547,0.25413257026133235,1.027635769907882,-0.7607655898218467,0.19067127264620573,0.12695555655645674,0.030894617027511038,0.2224334357534765,0.030894617027511038,7.00443820279511,-1.104482929673742,-0.931491220478586,0.6607309570482511,0.030894617027511038,-0.098122333905974,0.15884550726049723,-0.29373844618932715,-0.19560956934146895,0.030894617027511038,0.09500082791205905,1.2382387072449188,-0.6257295573052645,-0.13054795621506413,-0.16304347134508207,-0.42560918711049844,-0.098122333905974,-0.5587053640309138,-0.06576592628969985,-0.8287924672030076,0.09500082791205905,-0.3265940252928932,-0.22824695247054547,0.12695555655645674,0.25413257026133235,0.09500082791205905,-1.244601121096576,0.06298071889501843,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.8629365633590367,-0.03347806686168351,0.19067127264620573,0.6916031594494587,0.9670119136618348,-0.13054795621506413,0.2857692407025649,-0.3595238272390506,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.3595238272390506,0.5677772700633923,-0.098122333905974,-0.7947358122572576,0.9973494401983068,-1.174345720866778,6.233993929662534,0.6607309570482511,0.5055225334229401,0.34885740302862467,1.9718833674139287,-0.06576592628969985,-0.22824695247054547,-0.4587663248239629,-0.5921770650124923,3.6085359292973544,-0.06576592628969985,0.5988184783374502	3643
Cellular monovalent inorganic cation homeostasis	9	28	2.3310177466166504	0.0197524239233581	P55011,P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7	Processes and pathways	GO Biological process	msigdb_gobp	440,72,405,43,296,82,251,24,361	24,296,1962,2054,3149,2141,1144,3322,3197,72,2156,459,3075,440,2587,1036,965,1914,1331,82,2180,405,251,1274,2401,43,3315,361	4.11230346222967,0.9973494401983068,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.6593637349435877,0.7224199472328477,-0.3595238272390506,0.25413257026133235,0.2857692407025649,-0.098122333905974,0.12695555655645674,2.2010744460285183,-0.19560956934146895,0.7838890695289682,1.118191455601226,0.15884550726049723,-0.2609563355332265,3.2306497156014906,-0.8629365633590367,0.8756881681175116	3643
Positive regulation of intracellular signal transduction	30	160	2.3298711218473103	0.0198129637343913	O15344,Q86VI3,P14174,P14373,O00291,Q9NY93,Q9UMX5,P05067,P19474,Q8WVQ1,P02786,Q7Z434,O75116,P00813,P32929,Q13049,Q14457,P29372,P55735,Q13464,O43707,O60858,Q9Y4G8,Q13641,Q9NRA0,Q15555,O75569,Q9NWH9,O60826,P23246	Processes and pathways	GO Biological process	msigdb_gobp	253,140,15,395,390,429,27,29,36,423,409,420,293,56,187,188,189,438,201,328,325,80,81,329,227,355,350,371,247,375	1770,390,1605,2322,1209,1444,2793,1606,2050,1001,253,2501,2502,933,557,325,1138,1076,247,80,1614,293,2796,350,3068,1616,1783,56,409,2863,1288,1289,29,3218,1012,1789,1457,1081,653,2511,654,15,395,3629,1459,1794,3258,843,36,2225,2337,375,437,1223,3322,2658,438,1540,2066,2928,2874,3520,187,708,2229,2431,1547,3117,709,1887,1804,201,1808,1723,3118,1724,896,1985,2249,2078,2436,1156,2252,2769,1477,1560,2258,800,1893,1815,1310,506,3444,188,2884,715,3122,1994,328,2672,329,1563,189,854,355,2270,1038,1404,1098,1100,767,2001,3412,420,2460,140,2277,1108,1412,573,423,2178,813,2950,2613,1049,2542,1923,679,1187,863,3177,3235,3179,2738,984,522,3213,1847,2394,227,989,371,429,1431,738,1199,1065,27,2855,1599,874,3466,1132,81,2207,1951,1443,555,1860	-0.06576592628969985,0.7838890695289682,-0.0012581004565036626,-0.2609563355332265,0.15884550726049723,0.06298071889501843,-0.4920008457387619,-0.0012581004565036626,-0.16304347134508207,0.25413257026133235,1.08805639508316,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,0.5677772700633923,0.9366227945511973,0.19067127264620573,0.2224334357534765,1.118191455601226,2.2579809707838456,-0.0012581004565036626,0.9973494401983068,-0.4920008457387619,0.8756881681175116,-0.6593637349435877,-0.0012581004565036626,-0.06576592628969985,2.6800374279695216,0.7531817696547146,-0.525313577596298,0.12695555655645674,0.12695555655645674,3.6353042018995785,-0.7947358122572576,0.25413257026133235,-0.06576592628969985,0.06298071889501843,0.2224334357534765,0.47430803058067816,-0.3265940252928932,0.47430803058067816,4.964849362308119,0.7838890695289682,-2.997816021189173,0.06298071889501843,-0.06576592628969985,-0.8287924672030076,0.34885740302862467,3.3662912544280115,-0.22824695247054547,-0.2609563355332265,0.8145422833591529,0.7224199472328477,0.15884550726049723,-0.8971691305719629,-0.3925286203228279,0.7224199472328477,0.030894617027511038,-0.16304347134508207,-0.5587053640309138,-0.525313577596298,-1.315246174406957,1.387215394486587,0.44303477605405855,-0.22824695247054547,-0.29373844618932715,0.030894617027511038,-0.6930805097254553,0.44303477605405855,-0.098122333905974,-0.06576592628969985,1.327766595224347,-0.06576592628969985,-0.03347806686168351,-0.6930805097254553,-0.03347806686168351,0.31734400267200297,-0.13054795621506413,-0.22824695247054547,-0.16304347134508207,-0.29373844618932715,0.19067127264620573,-0.22824695247054547,-0.4587663248239629,0.06298071889501843,0.030894617027511038,-0.22824695247054547,0.3803099800917596,-0.098122333905974,-0.06576592628969985,0.12695555655645674,0.6298028841948623,-1.104482929673742,1.387215394486587,-0.525313577596298,0.44303477605405855,-0.6930805097254553,-0.13054795621506413,0.9366227945511973,-0.3925286203228279,0.9366227945511973,0.030894617027511038,1.387215394486587,0.34885740302862467,0.8756881681175116,-0.22824695247054547,0.25413257026133235,0.09500082791205905,0.2224334357534765,0.2224334357534765,0.4117022638315761,-0.13054795621506413,-1.0350054838275398,0.7531817696547146,-0.29373844618932715,1.623176179314646,-0.22824695247054547,0.2224334357534765,0.09500082791205905,0.5677772700633923,0.7531817696547146,-0.19560956934146895,0.3803099800917596,-0.5587053640309138,-0.3595238272390506,0.25413257026133235,-0.3265940252928932,-0.098122333905974,0.47430803058067816,0.19067127264620573,0.34885740302862467,-0.726880811724572,-0.7947358122572576,-0.726880811724572,-0.42560918711049844,0.2857692407025649,0.6298028841948623,-0.7607655898218467,-0.06576592628969985,-0.2609563355332265,1.2083001127798034,0.2857692407025649,0.845141841466991,0.7531817696547146,0.09500082791205905,0.44303477605405855,0.19067127264620573,0.25413257026133235,3.795309279757627,-0.4920008457387619,0.030894617027511038,0.34885740302862467,-1.1393655482262741,0.2224334357534765,2.2579809707838456,-0.19560956934146895,-0.098122333905974,0.09500082791205905,0.5988184783374502,-0.06576592628969985	3643
Mitochondrial transmembrane transport	13	57	2.3272540997522384	0.0199517451767423	Q9BSK2,O95563,P21796,Q9NWR8,P23786,P00846,Q9H4I9,O43772,O95831,P25705,O75027,O75964,Q8IYU8	Processes and pathways	GO Biological process	msigdb_gobp	260,152,34,305,200,74,244,13,47,237,21,214,257	1954,1283,13,2795,21,2137,1450,1218,214,1698,1372,152,47,500,74,1873,2141,3256,2331,1145,3544,34,200,3112,237,1226,3487,3264,2073,711,2522,2812,1649,2000,719,257,2949,2734,2468,3634,2906,682,320,3505,577,260,733,244,1057,3058,822,2485,305,924,2308,608,693	-0.13054795621506413,0.12695555655645674,5.243267115697605,-0.4920008457387619,4.373525061543824,-0.19560956934146895,0.06298071889501843,0.15884550726049723,1.2382387072449188,-0.03347806686168351,0.09500082791205905,1.5350292358486646,3.0119856905575273,0.6298028841948623,2.371337868662573,-0.098122333905974,-0.19560956934146895,-0.8287924672030076,-0.2609563355332265,0.19067127264620573,-1.421932600442622,3.528055524230381,1.327766595224347,-0.6930805097254553,1.1482768495977804,0.15884550726049723,-1.209424370050621,-0.8287924672030076,-0.16304347134508207,0.44303477605405855,-0.3265940252928932,-0.4920008457387619,-0.0012581004565036626,-0.13054795621506413,0.44303477605405855,1.08805639508316,-0.5587053640309138,-0.42560918711049844,-0.29373844618932715,-4.5798467158688725,-0.525313577596298,0.47430803058067816,0.9670119136618348,-1.244601121096576,0.5677772700633923,1.08805639508316,0.44303477605405855,1.1482768495977804,0.25413257026133235,-0.6257295573052645,0.3803099800917596,-0.29373844618932715,0.9973494401983068,0.31734400267200297,-0.22824695247054547,0.5366787829519797,0.47430803058067816	3643
Nuclear inner membrane	6	24	2.3250748499479297	0.0200679581992928	P20700,Q99720,Q9UH99,Q03252,Q14739,O75844	Localization	GO Cellular component	msigdb_gocc	310,2,170,207,416,248	248,2326,3102,310,1882,890,849,3161,2250,207,1237,624,416,3043,442,2780,1829,1664,1923,2,1581,1680,170,744	1.118191455601226,-0.2609563355332265,-0.6930805097254553,0.9670119136618348,-0.098122333905974,0.31734400267200297,0.34885740302862467,-0.726880811724572,-0.22824695247054547,1.2979715997804608,0.15884550726049723,0.5055225334229401,0.7531817696547146,-0.6257295573052645,0.7224199472328477,-0.4587663248239629,-0.06576592628969985,-0.0012581004565036626,-0.098122333905974,8.21990109917503,0.030894617027511038,-0.0012581004565036626,1.5055575321040489,0.44303477605405855	3643
Kinetic tremor	12	35	2.323103406357095	0.0201735980382442	P20700,Q14108,P07602,Q15233,Q9Y4W6,Q01082,Q9Y448,O75027,O43681,Q9BUB7,Q9NQH7,P41440	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	310,255,69,567,608,365,348,21,118,447,386,90	1862,1210,2571,118,21,2758,69,1874,2925,1222,310,1293,3028,592,1971,90,2877,1885,1088,365,955,255,567,2452,3393,859,1664,2622,447,386,1064,1521,3286,348,608	-0.098122333905974,0.15884550726049723,-0.3595238272390506,1.7982903969638317,4.373525061543824,-0.4587663248239629,2.427791890653298,-0.098122333905974,-0.5587053640309138,0.15884550726049723,0.9670119136618348,0.12695555655645674,-0.6257295573052645,0.5366787829519797,-0.13054795621506413,2.058127752852981,-0.525313577596298,-0.098122333905974,0.2224334357534765,0.845141841466991,0.2857692407025649,1.08805639508316,0.5677772700633923,-0.29373844618932715,-1.0004082879139022,0.34885740302862467,-0.0012581004565036626,-0.3595238272390506,0.7224199472328477,0.8145422833591529,0.25413257026133235,0.06298071889501843,-0.8287924672030076,0.9061816816409076,0.5366787829519797	3643
Babinski sign	17	91	2.320003571743724	0.0203406841204802	Q9NR77,P11166,Q99720,P20700,P07602,Q8N0X7,P00846,Q969N2,O75787,O95831,O75298,O75027,O43681,O14773,P41440,P07196,Q6DKK2	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,279,2,310,69,421,74,318,296,47,393,21,118,391,90,125,190	2321,646,2408,1862,435,391,1210,118,529,1865,2920,21,393,3144,296,2417,791,47,74,125,3151,69,1963,2655,3256,279,1876,2424,310,1796,2228,2971,753,1462,1542,1971,754,2431,3033,2232,1975,90,1467,3036,1301,2520,3626,1387,2349,2880,797,3471,801,1992,1238,963,964,3502,668,2452,190,2729,1407,2895,3393,421,859,2098,1918,2012,813,3173,2378,318,2381,2289,2,2112,2193,579,32,2556,1849,1064,1521,3519,1274,2562,1690,1203,608	-0.2609563355332265,0.47430803058067816,-0.29373844618932715,-0.098122333905974,0.7224199472328477,0.7838890695289682,0.15884550726049723,1.7982903969638317,0.5988184783374502,-0.098122333905974,-0.5587053640309138,4.373525061543824,0.7838890695289682,-0.726880811724572,0.9973494401983068,-0.29373844618932715,0.3803099800917596,3.0119856905575273,2.371337868662573,1.7400910153055076,-0.726880811724572,2.427791890653298,-0.13054795621506413,-0.3925286203228279,-0.8287924672030076,1.027635769907882,-0.098122333905974,-0.29373844618932715,0.9670119136618348,-0.06576592628969985,-0.22824695247054547,-0.5921770650124923,0.4117022638315761,0.06298071889501843,0.030894617027511038,-0.13054795621506413,0.4117022638315761,-0.29373844618932715,-0.6257295573052645,-0.22824695247054547,-0.13054795621506413,2.058127752852981,0.06298071889501843,-0.6257295573052645,0.12695555655645674,-0.3265940252928932,-2.919565762049335,0.09500082791205905,-0.2609563355332265,-0.525313577596298,0.3803099800917596,-1.174345720866778,0.3803099800917596,-0.13054795621506413,0.15884550726049723,0.2857692407025649,0.2857692407025649,-1.244601121096576,0.47430803058067816,-0.29373844618932715,1.387215394486587,-0.42560918711049844,0.09500082791205905,-0.525313577596298,-1.0004082879139022,0.7531817696547146,0.34885740302862467,-0.16304347134508207,-0.098122333905974,-0.13054795621506413,0.3803099800917596,-0.726880811724572,-0.2609563355332265,0.9670119136618348,-0.2609563355332265,-0.22824695247054547,8.21990109917503,-0.16304347134508207,-0.19560956934146895,0.5677772700633923,3.6085359292973544,-0.3265940252928932,-0.06576592628969985,0.25413257026133235,0.06298071889501843,-1.2798752825252815,0.15884550726049723,-0.3265940252928932,-0.0012581004565036626,0.19067127264620573,0.5366787829519797	3643
Abnormality of the ribs	19	71	2.318804030462296	0.0204056645675847	Q7RTS9,P02545,P54802,Q9UBM7,P16278,Q9UHX1,Q96L58,P15586,O75718,Q14739,O95831,P00813,O00754,O95155,O75431,O96028,Q96HY6,O60826,O75844	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	11,265,147,289,155,171,303,410,295,416,47,56,435,307,213,87,384,247,248	435,3610,1210,2502,247,1005,2412,499,213,3216,295,248,3288,307,1372,47,87,56,265,3150,410,155,2145,1707,2061,2337,2927,2516,707,3297,3557,1886,1155,460,147,2434,2257,1989,1815,3270,801,1562,416,2887,1566,2889,1038,2728,2364,569,1172,3475,2003,11,1500,974,2610,2612,2183,384,303,2736,3001,2478,1852,289,171,2959,3012,1069,693	0.7224199472328477,-2.1540615170130093,0.15884550726049723,-0.3265940252928932,1.118191455601226,0.25413257026133235,-0.29373844618932715,0.6298028841948623,1.2382387072449188,-0.7947358122572576,0.9973494401983068,1.118191455601226,-0.8629365633590367,0.9670119136618348,0.09500082791205905,3.0119856905575273,2.11542427763213,2.6800374279695216,1.0578712931665288,-0.726880811724572,0.7531817696547146,1.5350292358486646,-0.19560956934146895,-0.03347806686168351,-0.16304347134508207,-0.2609563355332265,-0.5587053640309138,-0.3265940252928932,0.44303477605405855,-0.8629365633590367,-1.4935285643358234,-0.098122333905974,0.19067127264620573,0.6916031594494587,1.5644560394229112,-0.29373844618932715,-0.22824695247054547,-0.13054795621506413,-0.06576592628969985,-0.8287924672030076,0.3803099800917596,0.030894617027511038,0.7531817696547146,-0.525313577596298,0.030894617027511038,-0.525313577596298,0.25413257026133235,-0.42560918711049844,-0.2609563355332265,0.5677772700633923,0.19067127264620573,-1.174345720866778,-0.13054795621506413,5.543953911878619,0.06298071889501843,0.2857692407025649,-0.3595238272390506,-0.3595238272390506,-0.19560956934146895,0.8145422833591529,0.9973494401983068,-0.42560918711049844,-0.5921770650124923,-0.29373844618932715,-0.06576592628969985,1.027635769907882,1.5055575321040489,-0.5587053640309138,-0.5921770650124923,0.25413257026133235,0.47430803058067816	3643
Limb girdle muscle weakness	10	28	2.31778806641995	0.0204608419862537	P07602,Q8TD16,Q7LG56,Q14331,P02545,P06753,Q9H9S5,Q13126,Q96RR1,Q13049	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	69,272,464,477,265,394,347,20,319,188	2210,1000,529,2136,3404,265,394,69,2331,890,2432,2073,2242,2349,2358,188,20,2529,477,1165,464,272,319,347,1064,2960,1604,1068	-0.22824695247054547,0.25413257026133235,0.5988184783374502,-0.19560956934146895,-1.0350054838275398,1.0578712931665288,0.7838890695289682,2.427791890653298,-0.2609563355332265,0.31734400267200297,-0.29373844618932715,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,-0.2609563355332265,1.387215394486587,4.39950530014643,-0.3265940252928932,0.6607309570482511,0.19067127264620573,0.6916031594494587,1.0578712931665288,0.9670119136618348,0.9061816816409076,0.25413257026133235,-0.5587053640309138,0.030894617027511038,0.25413257026133235	3643
Protease binding	7	33	2.3041592990294024	0.0212137030089223	P46379,P07602,O75251,P14174,P25705,O75955,P41440	Functions	GO Molecular function	msigdb_gomf	3,69,294,15,237,249,90	294,249,3617,2758,1288,3218,1012,3191,69,15,237,3424,2343,90,3,1801,2242,2349,952,1093,3082,1096,2890,1652,3045,2989,1674,319,3177,3056,1064,1593,1437	0.9973494401983068,1.118191455601226,-2.342454069604444,-0.4587663248239629,0.12695555655645674,-0.7947358122572576,0.25413257026133235,-0.7607655898218467,2.427791890653298,4.964849362308119,1.1482768495977804,-1.069696640684267,-0.2609563355332265,2.058127752852981,7.00443820279511,-0.06576592628969985,-0.22824695247054547,-0.2609563355332265,0.2857692407025649,0.2224334357534765,-0.6593637349435877,0.2224334357534765,-0.525313577596298,-0.0012581004565036626,-0.6257295573052645,-0.5921770650124923,-0.0012581004565036626,0.9670119136618348,-0.726880811724572,-0.6257295573052645,0.25413257026133235,0.030894617027511038,0.09500082791205905	3643
Hydrolase activity acting on glycosyl bonds	13	31	2.3040710729852028	0.0212186542459933	P16278,P23396,O00754,P04066,Q9BTY2,O60476,P08236,P10253,O60502,P54802,O75503,P06280,P29372	Functions	GO Molecular function	msigdb_gomf	155,437,435,228,115,264,455,266,84,147,24,153,438	435,1282,264,84,24,703,228,153,1013,3538,455,266,2512,3513,155,2869,437,3073,438,1383,1623,147,1892,3490,1997,3205,478,2455,2988,115,1757	0.7224199472328477,0.12695555655645674,1.0578712931665288,2.144013371443563,4.11230346222967,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-1.3862754857551036,0.6916031594494587,1.0578712931665288,-0.3265940252928932,-1.2798752825252815,1.5350292358486646,-0.525313577596298,0.7224199472328477,-0.6593637349435877,0.7224199472328477,0.09500082791205905,-0.0012581004565036626,1.5644560394229112,-0.098122333905974,-1.209424370050621,-0.13054795621506413,-0.7607655898218467,0.6607309570482511,-0.29373844618932715,-0.5921770650124923,1.8563207862044178,-0.03347806686168351	3643
Membrane protein proteolysis	9	14	2.304063453212541	0.0212190819141178	P35579,Q9Y5X1,Q9NZ08,Q13464,Q16740,P78536,Q92542,Q9H300,Q8TCT8	Processes and pathways	GO Biological process	msigdb_gobp	280,107,245,328,113,216,317,491,158	1137,280,1150,216,328,113,158,3492,317,491,245,1854,608,107	0.19067127264620573,1.027635769907882,0.19067127264620573,1.2382387072449188,0.9366227945511973,1.8563207862044178,1.5350292358486646,-1.209424370050621,0.9670119136618348,0.6607309570482511,1.1482768495977804,-0.06576592628969985,0.5366787829519797,1.943054324684516	3643
Transforming growth factor beta receptor signaling pathway	6	31	2.3006298174933937	0.021412564149345	Q8WUH2,Q06481,Q92896,Q8N3R9,Q13573,P78536	Processes and pathways	GO Biological process	msigdb_gobp	133,39,136,148,88,216	2322,2049,2502,1288,3218,1457,1791,3520,1296,229,1155,2436,216,39,2671,88,2270,2271,1909,148,133,136,2378,1049,1923,2562,1855,3138,744,2406,1132	-0.2609563355332265,-0.16304347134508207,-0.3265940252928932,0.12695555655645674,-0.7947358122572576,0.06298071889501843,-0.06576592628969985,-1.315246174406957,0.12695555655645674,1.1783129469800828,0.19067127264620573,-0.29373844618932715,1.2382387072449188,3.257840018273795,-0.3925286203228279,2.11542427763213,-0.22824695247054547,-0.22824695247054547,-0.098122333905974,1.5644560394229112,1.6817203809689008,1.6524701228970238,-0.2609563355332265,0.25413257026133235,-0.098122333905974,-0.3265940252928932,-0.06576592628969985,-0.6930805097254553,0.44303477605405855,-0.2609563355332265,0.2224334357534765	3643
Trans golgi network vesicle budding	12	42	2.296564553952842	0.0216436226521594	P11717,P20645,P51809,P02786,Q9Y5X1,P15586,O43493,O75976,Q99523,O14976,Q9H3P7,P05067	Processes and pathways	Reactome Pathways	msigdb_reactome	154,37,476,409,107,410,142,206,114,392,523,29	2321,1952,834,1774,392,142,2963,2860,588,1367,206,409,29,1702,1703,2144,154,410,37,1155,1300,476,1556,1889,2768,3571,952,2257,1160,1727,2596,2088,3600,1663,3355,515,2014,114,1933,523,107,2407	-0.2609563355332265,-0.13054795621506413,0.34885740302862467,-0.06576592628969985,0.7838890695289682,1.5938382520831849,-0.5921770650124923,-0.525313577596298,0.5366787829519797,0.09500082791205905,1.2979715997804608,0.7531817696547146,3.6353042018995785,-0.03347806686168351,-0.03347806686168351,-0.19560956934146895,1.5350292358486646,0.7531817696547146,3.284999162596966,0.19067127264620573,0.12695555655645674,0.6607309570482511,0.030894617027511038,-0.098122333905974,-0.4587663248239629,-1.5654960467228805,0.2857692407025649,-0.22824695247054547,0.19067127264620573,-0.03347806686168351,-0.3595238272390506,-0.16304347134508207,-1.8938214246167355,-0.0012581004565036626,-0.931491220478586,0.6298028841948623,-0.13054795621506413,1.8563207862044178,-0.098122333905974,0.6298028841948623,1.943054324684516,-0.2609563355332265	3643
Protein processing	18	51	2.284054095375942	0.0223683519418589	P35579,Q9Y366,Q92896,P17655,O75787,Q15392,O75976,Q96F07,Q9BXS4,Q9H9S5,P42892,O75503,Q9NQH7,O75844,Q92542,Q9H300,Q969M3,P78536	Processes and pathways	GO Biological process	msigdb_gobp	280,290,136,473,296,45,206,344,50,347,53,24,386,248,317,491,356,216	3101,2137,24,296,248,206,2799,3148,3190,3191,1791,3406,473,3470,280,53,3298,2244,2245,2254,216,658,1561,2986,45,3501,1652,1042,3085,2989,1500,3492,317,136,356,344,2833,1264,520,2737,3179,50,491,347,2842,386,2400,2308,3285,290,608	-0.6930805097254553,-0.19560956934146895,4.11230346222967,0.9973494401983068,1.118191455601226,1.2979715997804608,-0.4920008457387619,-0.726880811724572,-0.7607655898218467,-0.7607655898218467,-0.06576592628969985,-1.0350054838275398,0.6607309570482511,-1.174345720866778,1.027635769907882,2.763483088965262,-0.8629365633590367,-0.22824695247054547,-0.22824695247054547,-0.22824695247054547,1.2382387072449188,0.47430803058067816,0.030894617027511038,-0.5921770650124923,3.1215736355280526,-1.244601121096576,-0.0012581004565036626,0.25413257026133235,-0.6593637349435877,-0.5921770650124923,0.06298071889501843,-1.209424370050621,0.9670119136618348,1.6524701228970238,0.8756881681175116,0.9061816816409076,-0.4920008457387619,0.15884550726049723,0.6298028841948623,-0.42560918711049844,-0.726880811724572,2.901874777421383,0.6607309570482511,0.9061816816409076,-0.4920008457387619,0.8145422833591529,-0.2609563355332265,-0.22824695247054547,-0.8287924672030076,1.027635769907882,0.5366787829519797	3643
Monovalent inorganic cation homeostasis	9	32	2.282382165176677	0.0224667873589194	P55011,P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7	Processes and pathways	GO Biological process	msigdb_gobp	440,72,405,43,296,82,251,24,361	24,296,1289,1962,2054,3149,2141,1144,3322,3197,72,2156,459,3075,440,2587,1036,965,1914,1331,82,2612,2180,405,251,1274,2401,43,2407,694,3315,361	4.11230346222967,0.9973494401983068,0.12695555655645674,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.6593637349435877,0.7224199472328477,-0.3595238272390506,0.25413257026133235,0.2857692407025649,-0.098122333905974,0.12695555655645674,2.2010744460285183,-0.3595238272390506,-0.19560956934146895,0.7838890695289682,1.118191455601226,0.15884550726049723,-0.2609563355332265,3.2306497156014906,-0.2609563355332265,0.47430803058067816,-0.8629365633590367,0.8756881681175116	3643
Muscle stiffness	8	22	2.282029852542516	0.0224875778450048	P11166,P07602,P23786,P00846,P53985,Q15392,P52732,P06753	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	279,69,200,74,44,45,326,394	3363,2652,74,394,69,279,200,1717,412,326,44,2242,797,45,2729,1915,2011,2112,3535,1064,3519,1692	-0.9659039071751861,-0.3925286203228279,2.371337868662573,0.7838890695289682,2.427791890653298,1.027635769907882,1.327766595224347,-0.03347806686168351,0.7531817696547146,0.9366227945511973,3.1215736355280526,-0.22824695247054547,0.3803099800917596,3.1215736355280526,-0.42560918711049844,-0.098122333905974,-0.13054795621506413,-0.16304347134508207,-1.3507131280591325,0.25413257026133235,-1.2798752825252815,-0.0012581004565036626	3643
External side of plasma membrane	12	27	2.281681984814331	0.0225081224375096	P02786,P17655,P30511,O75787,Q01650,P51790,P15291,P42892,O75955,P00813,P00390,P41440	Localization	GO Cellular component	msigdb_gocc	409,473,138,296,143,459,112,53,249,56,25,90	1003,296,249,3365,25,56,3617,409,2508,3218,1012,3150,1374,1082,2760,112,942,473,2658,138,90,53,2236,459,143,1031,512	0.25413257026133235,0.9973494401983068,1.118191455601226,-0.9659039071751861,3.9014137223503935,2.6800374279695216,-2.342454069604444,0.7531817696547146,-0.3265940252928932,-0.7947358122572576,0.25413257026133235,-0.726880811724572,0.09500082791205905,0.2224334357534765,-0.4587663248239629,1.8563207862044178,0.2857692407025649,0.6607309570482511,-0.3925286203228279,1.623176179314646,2.058127752852981,2.763483088965262,-0.22824695247054547,0.6916031594494587,1.5938382520831849,0.25413257026133235,0.6298028841948623	3643
Regulation of synapse structure or activity	10	34	2.281464425611921	0.0225209794774776	Q14012,P50897,Q9BQT9,Q14203,Q13641,Q15375,Q12834,Q7L576,Q9UQB8,P05067	Processes and pathways	GO Biological process	msigdb_gobp	379,72,275,415,329,418,284,340,26,29	932,29,1701,2144,3221,843,3111,2974,72,2349,1723,1023,3077,2437,3079,2721,284,329,379,415,1564,418,1097,1567,340,1186,2624,275,1056,522,3063,1853,743,26	0.2857692407025649,3.6353042018995785,-0.03347806686168351,-0.19560956934146895,-0.7947358122572576,0.34885740302862467,-0.6930805097254553,-0.5921770650124923,2.399583395405736,-0.2609563355332265,-0.03347806686168351,0.25413257026133235,-0.6593637349435877,-0.29373844618932715,-0.6593637349435877,-0.42560918711049844,1.027635769907882,0.9366227945511973,0.8145422833591529,0.7531817696547146,0.030894617027511038,0.7531817696547146,0.2224334357534765,0.030894617027511038,0.9061816816409076,0.19067127264620573,-0.3595238272390506,1.0578712931665288,0.25413257026133235,0.6298028841948623,-0.6257295573052645,-0.06576592628969985,0.44303477605405855,3.9014137223503935	3643
Response to transforming growth factor beta	8	39	2.278290507457164	0.0227092748561041	Q8WUH2,P49354,Q06481,Q92896,O75116,Q8N3R9,Q13573,P78536	Processes and pathways	GO Biological process	msigdb_gobp	133,229,39,136,293,148,88,216	2322,2134,2049,2502,293,1288,3218,1457,1791,3520,1296,2712,3117,229,1155,2436,216,39,1479,328,2671,88,2270,2271,1909,148,133,1749,136,2378,1049,1923,1192,2562,1855,3138,744,2406,1132	-0.2609563355332265,-0.19560956934146895,-0.16304347134508207,-0.3265940252928932,0.9973494401983068,0.12695555655645674,-0.7947358122572576,0.06298071889501843,-0.06576592628969985,-1.315246174406957,0.12695555655645674,-0.42560918711049844,-0.6930805097254553,1.1783129469800828,0.19067127264620573,-0.29373844618932715,1.2382387072449188,3.257840018273795,0.06298071889501843,0.9366227945511973,-0.3925286203228279,2.11542427763213,-0.22824695247054547,-0.22824695247054547,-0.098122333905974,1.5644560394229112,1.6817203809689008,-0.03347806686168351,1.6524701228970238,-0.2609563355332265,0.25413257026133235,-0.098122333905974,0.19067127264620573,-0.3265940252928932,-0.06576592628969985,-0.6930805097254553,0.44303477605405855,-0.2609563355332265,0.2224334357534765	3643
Lipid localization	16	94	2.276458301057388	0.0228185936520393	Q9H4L5,Q99720,Q14108,P11166,P07602,P22466,O15118,Q8WTV0,P23786,P61916,Q16739,O15260,O43772,P14174,O14678,P35790	Processes and pathways	GO Biological process	msigdb_gobp	100,2,255,279,69,38,252,8,200,351,330,108,13,15,176,51	1206,3527,453,176,252,108,1003,13,2754,1214,1369,1455,1286,2221,2651,2653,3617,1787,703,2508,1012,3191,69,3538,1874,1374,1704,279,15,2869,1797,1293,38,200,1622,3615,592,364,1224,2342,1225,51,2934,3264,351,2881,2163,1392,2938,1815,255,2673,3301,330,3042,3371,2001,3456,810,3593,2900,8,1336,1923,574,1263,2,3630,2688,3553,1347,984,3209,549,2388,1350,100,1937,686,2912,3337,1432,1064,1199,1273,742,1946,2308,1764,2309,3380,874,995,876	0.15884550726049723,-1.3507131280591325,0.6916031594494587,1.446478167816503,1.08805639508316,1.914184390727662,0.25413257026133235,5.243267115697605,-0.4587663248239629,0.15884550726049723,0.09500082791205905,0.06298071889501843,0.12695555655645674,-0.22824695247054547,-0.3925286203228279,-0.3925286203228279,-2.342454069604444,-0.06576592628969985,0.44303477605405855,-0.3265940252928932,0.25413257026133235,-0.7607655898218467,2.427791890653298,-1.3862754857551036,-0.098122333905974,0.09500082791205905,-0.03347806686168351,1.027635769907882,4.964849362308119,-0.525313577596298,-0.06576592628969985,0.12695555655645674,3.257840018273795,1.327766595224347,-0.0012581004565036626,-2.2291720974867153,0.5366787829519797,0.845141841466991,0.15884550726049723,-0.2609563355332265,0.15884550726049723,2.8742639930235563,-0.5587053640309138,-0.8287924672030076,0.8756881681175116,-0.525313577596298,-0.19560956934146895,0.09500082791205905,-0.5587053640309138,-0.06576592628969985,1.08805639508316,-0.3925286203228279,-0.8629365633590367,0.9366227945511973,-0.6257295573052645,-0.9659039071751861,-0.13054795621506413,-1.1393655482262741,0.3803099800917596,-1.7470088834303552,-0.525313577596298,5.940175937290734,0.12695555655645674,-0.098122333905974,0.5677772700633923,0.15884550726049723,8.21990109917503,-3.1552041982193537,-0.3925286203228279,-1.4576838354723742,0.12695555655645674,0.2857692407025649,-0.7607655898218467,0.5988184783374502,-0.2609563355332265,0.12695555655645674,1.9718833674139287,-0.098122333905974,0.47430803058067816,-0.525313577596298,-0.8971691305719629,0.09500082791205905,0.25413257026133235,0.19067127264620573,0.15884550726049723,0.44303477605405855,-0.098122333905974,-0.22824695247054547,-0.03347806686168351,-0.22824695247054547,-0.9659039071751861,0.34885740302862467,0.2857692407025649,0.34885740302862467	3643
Abnormal biliary tract morphology	6	26	2.2736693864256803	0.0229858721427238	Q14108,P07602,O15078,P14174,O43681,Q9NUN5	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	255,69,194,15,118,123	194,118,265,703,69,653,15,3437,1973,3155,1802,2238,2242,658,803,255,416,1491,2378,2621,2483,123,1064,1202,2789,1604	1.3575144142492008,1.7982903969638317,1.0578712931665288,0.44303477605405855,2.427791890653298,0.47430803058067816,4.964849362308119,-1.104482929673742,-0.13054795621506413,-0.726880811724572,-0.06576592628969985,-0.22824695247054547,-0.22824695247054547,0.47430803058067816,0.3803099800917596,1.08805639508316,0.7531817696547146,0.06298071889501843,-0.2609563355332265,-0.3595238272390506,-0.29373844618932715,1.7692119702003737,0.25413257026133235,0.19067127264620573,-0.4587663248239629,0.030894617027511038	3643
Membrane protein ectodomain proteolysis	6	11	2.271691967371752	0.0231051216933753	P35579,Q9Y5X1,Q9NZ08,P78536,Q92542,Q8TCT8	Processes and pathways	GO Biological process	msigdb_gobp	280,107,245,216,317,158	1137,280,1150,216,328,158,3492,317,245,1854,107	0.19067127264620573,1.027635769907882,0.19067127264620573,1.2382387072449188,0.9366227945511973,1.5350292358486646,-1.209424370050621,0.9670119136618348,1.1482768495977804,-0.06576592628969985,1.943054324684516	3643
Abnormal circulating lipid concentration	21	79	2.268173533011974	0.0233186319409635	P22830,O43772,P02545,Q9UBM7,P06280,P49748,P28070,Q15392,Q14739,Q969N2,P07602,Q15056,P23786,Q03252,O43707,O75431,P61916,P31751,O75844,Q9NUN5,Q9UIG0	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	0,13,265,289,153,412,164,45,416,318,69,462,200,207,325,213,351,364,248,123,527	1210,325,1610,13,3483,213,2647,248,1451,1285,701,3617,265,153,1011,69,2143,3623,2333,0,200,164,888,364,3514,3199,1623,3343,2150,3578,1464,2232,1467,794,412,849,3264,1802,3386,2238,2716,2880,798,351,1089,2257,207,1159,507,3328,959,416,462,45,1566,3168,2532,965,2942,1170,1914,3132,3517,976,813,318,1581,3001,3280,123,1197,1064,289,527,924,1130,1603,1604,876	0.15884550726049723,0.9366227945511973,-0.0012581004565036626,5.243267115697605,-1.209424370050621,1.2382387072449188,-0.3925286203228279,1.118191455601226,0.06298071889501843,0.12695555655645674,0.44303477605405855,-2.342454069604444,1.0578712931665288,1.5350292358486646,0.25413257026133235,2.427791890653298,-0.19560956934146895,-2.7252579017752425,-0.2609563355332265,9.72862962082004,1.327766595224347,1.5055575321040489,0.31734400267200297,0.845141841466991,-1.2798752825252815,-0.7607655898218467,-0.0012581004565036626,-0.931491220478586,-0.19560956934146895,-1.63783022894056,0.06298071889501843,-0.22824695247054547,0.06298071889501843,0.3803099800917596,0.7531817696547146,0.34885740302862467,-0.8287924672030076,-0.06576592628969985,-1.0004082879139022,-0.22824695247054547,-0.42560918711049844,-0.525313577596298,0.3803099800917596,0.8756881681175116,0.2224334357534765,-0.22824695247054547,1.2979715997804608,0.19067127264620573,0.6298028841948623,-0.8971691305719629,0.2857692407025649,0.7531817696547146,0.6916031594494587,3.1215736355280526,0.030894617027511038,-0.726880811724572,-0.3265940252928932,0.2857692407025649,-0.5587053640309138,0.19067127264620573,-0.098122333905974,-0.6930805097254553,-1.2798752825252815,0.2857692407025649,0.3803099800917596,0.9670119136618348,0.030894617027511038,-0.5921770650124923,-0.8287924672030076,1.7692119702003737,0.19067127264620573,0.25413257026133235,1.027635769907882,0.6298028841948623,0.31734400267200297,0.2224334357534765,0.030894617027511038,0.030894617027511038,0.34885740302862467	3643
Adaptive immune response	15	49	2.2616840542464733	0.0237169306173579	Q9UQ84,Q9NUQ9,P10321,Q9BY67,P02786,Q9NZ08,P30511,Q9NQT5,O15400,P14373,P04439,P00813,Q9BX67,O96028,P78536	Processes and pathways	GO Biological process	msigdb_gobp	33,102,532,304,409,245,138,638,586,395,590,56,488,87,216	586,2502,1217,87,3147,56,1872,409,2508,590,1081,532,3256,1704,3513,395,138,2229,1385,1296,1547,1086,1548,1553,1632,216,3038,1028,2938,1310,2526,1031,1404,2535,969,2776,1737,1923,681,3311,914,1928,488,304,638,102,245,3063,33	0.5366787829519797,-0.3265940252928932,0.15884550726049723,2.11542427763213,-0.726880811724572,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,0.5988184783374502,-0.8287924672030076,-0.03347806686168351,-1.2798752825252815,0.7838890695289682,1.623176179314646,-0.22824695247054547,0.09500082791205905,0.12695555655645674,0.030894617027511038,0.2224334357534765,0.030894617027511038,0.030894617027511038,-0.0012581004565036626,1.2382387072449188,-0.6257295573052645,0.25413257026133235,-0.5587053640309138,0.12695555655645674,-0.3265940252928932,0.25413257026133235,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.4587663248239629,-0.03347806686168351,-0.098122333905974,0.47430803058067816,-0.8629365633590367,0.31734400267200297,-0.098122333905974,0.6607309570482511,0.9973494401983068,0.5055225334229401,1.9718833674139287,1.1482768495977804,-0.6257295573052645,3.6085359292973544	3643
Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	11	37	2.258772732604993	0.0238975255049214	Q9UQ84,Q9NUQ9,Q9BY67,P02786,P30511,Q9NQT5,P04439,P00813,O15400,O96028,P78536	Processes and pathways	GO Biological process	msigdb_gobp	33,102,304,409,138,638,590,56,586,87,216	586,2502,1217,87,3147,56,1872,409,2508,590,1081,3256,1704,3513,138,2229,1385,1296,1086,1548,1553,1632,216,2938,1310,2526,1404,2535,969,1737,681,914,1928,304,638,102,33	0.5366787829519797,-0.3265940252928932,0.15884550726049723,2.11542427763213,-0.726880811724572,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,-0.8287924672030076,-0.03347806686168351,-1.2798752825252815,1.623176179314646,-0.22824695247054547,0.09500082791205905,0.12695555655645674,0.2224334357534765,0.030894617027511038,0.030894617027511038,-0.0012581004565036626,1.2382387072449188,-0.5587053640309138,0.12695555655645674,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.47430803058067816,0.31734400267200297,-0.098122333905974,0.9973494401983068,0.5055225334229401,1.9718833674139287,3.6085359292973544	3643
Myotube differentiation	6	17	2.2585849424932176	0.0239092153265887	P35579,Q8IV08,Q96TA1,Q99523,O75955,P41440	Processes and pathways	GO Biological process	msigdb_gobp	280,73,333,114,249,90	249,3218,473,280,90,1086,3270,1816,1165,1097,73,333,114,1422,1937,2031,2036	1.118191455601226,-0.7947358122572576,0.6607309570482511,1.027635769907882,2.058127752852981,0.2224334357534765,-0.8287924672030076,-0.06576592628969985,0.19067127264620573,0.2224334357534765,2.399583395405736,0.9366227945511973,1.8563207862044178,0.09500082791205905,-0.098122333905974,-0.13054795621506413,-0.13054795621506413	3643
Protein homooligomerization	6	48	2.250673976452344	0.0244061941805455	Q99720,Q06481,O94788,Q4G0X4,P14174,P32929	Processes and pathways	GO Biological process	msigdb_gobp	2,39,9,91,15,187	3527,2963,9,3364,1372,3147,2922,3291,2576,15,187,1970,1542,754,1150,3439,2158,2982,39,3166,414,2526,3606,211,1732,662,91,3391,1825,3305,1255,2734,1669,2382,2624,3178,2,2737,2738,320,447,549,490,1937,2199,3519,926,1692	-1.3507131280591325,-0.5921770650124923,5.816916168706705,-0.9659039071751861,0.09500082791205905,-0.726880811724572,-0.5587053640309138,-0.8629365633590367,-0.3595238272390506,4.964849362308119,1.387215394486587,-0.13054795621506413,0.030894617027511038,0.4117022638315761,0.19067127264620573,-1.104482929673742,-0.19560956934146895,-0.5921770650124923,3.257840018273795,-0.726880811724572,0.7531817696547146,-0.3265940252928932,-1.9677499058145898,1.268129085929357,-0.03347806686168351,0.47430803058067816,2.058127752852981,-1.0004082879139022,-0.06576592628969985,-0.8629365633590367,0.15884550726049723,-0.42560918711049844,-0.0012581004565036626,-0.2609563355332265,-0.3595238272390506,-0.726880811724572,8.21990109917503,-0.42560918711049844,-0.42560918711049844,0.9670119136618348,0.7224199472328477,0.5988184783374502,0.6607309570482511,-0.098122333905974,-0.19560956934146895,-1.2798752825252815,0.31734400267200297,-0.0012581004565036626	3643
Rhoa gtpase cycle	14	52	2.249598224187769	0.0244744612896241	P41440,O15173,P02786,Q86VI3,Q86UP2,Q07960,Q13464,P30519,O75116,O75955,Q96HY6,Q92888,P11274,Q8NBN3	Processes and pathways	Reactome Pathways	msigdb_reactome	90,199,409,140,301,298,328,14,293,249,384,424,338,225	645,199,2213,789,1534,293,249,1782,409,338,3468,563,1622,14,90,793,2344,709,794,1887,2240,3120,1310,298,3444,1643,2940,3121,328,3225,1315,416,965,1404,855,301,140,225,974,1330,424,1834,1835,384,863,1424,2389,3568,2556,988,3007,2037	0.47430803058067816,1.327766595224347,-0.22824695247054547,0.3803099800917596,0.030894617027511038,0.9973494401983068,1.118191455601226,-0.06576592628969985,0.7531817696547146,0.9061816816409076,-1.174345720866778,0.5677772700633923,-0.0012581004565036626,5.1928477731586264,2.058127752852981,0.3803099800917596,-0.2609563355332265,0.44303477605405855,0.3803099800917596,-0.098122333905974,-0.22824695247054547,-0.6930805097254553,0.12695555655645674,0.9973494401983068,-1.104482929673742,-0.0012581004565036626,-0.5587053640309138,-0.6930805097254553,0.9366227945511973,-0.7947358122572576,0.12695555655645674,0.7531817696547146,0.2857692407025649,0.09500082791205905,0.34885740302862467,0.9973494401983068,1.623176179314646,1.2083001127798034,0.2857692407025649,0.12695555655645674,0.7531817696547146,-0.06576592628969985,-0.06576592628969985,0.8145422833591529,0.34885740302862467,0.09500082791205905,-0.2609563355332265,-1.5294661704120023,-0.3265940252928932,0.2857692407025649,-0.5921770650124923,-0.13054795621506413	3643
Carbohydrate derivative transport	6	23	2.2483067072085428	0.0245566393279113	Q86VD7,P07602,P61916,Q8WTV0,Q9HC21,P41440	Processes and pathways	GO Biological process	msigdb_gobp	256,69,351,8,553,90	2751,646,1003,2754,1873,69,2331,1145,90,351,1395,2274,2366,256,1177,573,2829,8,1336,2292,553,1432,1064	-0.4587663248239629,0.47430803058067816,0.25413257026133235,-0.4587663248239629,-0.098122333905974,2.427791890653298,-0.2609563355332265,0.19067127264620573,2.058127752852981,0.8756881681175116,0.09500082791205905,-0.22824695247054547,-0.2609563355332265,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,5.940175937290734,0.12695555655645674,-0.22824695247054547,0.5988184783374502,0.09500082791205905,0.25413257026133235	3643
Joint contracture of the hand	13	57	2.247507388913387	0.0246076188966879	Q9NR77,O95155,Q8WVQ1,Q8IZA0,Q15392,P02545,Q71SY5,P06753,P42892,O75530,O75844,P11274,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,307,423,141,45,265,144,394,53,86,248,338,125	1210,2919,2502,2794,499,86,248,307,265,394,125,338,2145,2925,2337,2927,844,3197,2711,1546,53,3117,1802,2667,798,2257,3328,1646,959,899,3389,765,45,1038,1172,3304,2893,144,141,1668,423,2541,2017,728,2736,2021,447,2193,869,32,1853,2041,2854,2565,1279,1767,693	0.15884550726049723,-0.5587053640309138,-0.3265940252928932,-0.4920008457387619,0.6298028841948623,2.11542427763213,1.118191455601226,0.9670119136618348,1.0578712931665288,0.7838890695289682,1.7400910153055076,0.9061816816409076,-0.19560956934146895,-0.5587053640309138,-0.2609563355332265,-0.5587053640309138,0.34885740302862467,-0.7607655898218467,-0.42560918711049844,0.030894617027511038,2.763483088965262,-0.6930805097254553,-0.06576592628969985,-0.3925286203228279,0.3803099800917596,-0.22824695247054547,-0.8971691305719629,-0.0012581004565036626,0.2857692407025649,0.31734400267200297,-1.0004082879139022,0.4117022638315761,3.1215736355280526,0.25413257026133235,0.19067127264620573,-0.8629365633590367,-0.525313577596298,1.5938382520831849,1.623176179314646,-0.0012581004565036626,0.7531817696547146,-0.3265940252928932,-0.13054795621506413,0.44303477605405855,-0.42560918711049844,-0.13054795621506413,0.7224199472328477,-0.19560956934146895,0.34885740302862467,3.6085359292973544,-0.06576592628969985,-0.13054795621506413,-0.4920008457387619,-0.3265940252928932,0.15884550726049723,-0.03347806686168351,0.47430803058067816	3643
Positive regulation of adaptive immune response	7	18	2.246702728013067	0.0246590317976038	Q9NUQ9,P02786,P30511,P04439,P00813,O15400,O96028	Processes and pathways	GO Biological process	msigdb_gobp	102,409,138,590,56,586,87	586,2502,87,56,1872,409,590,3256,138,1548,2526,2535,969,1923,914,1928,638,102	0.5366787829519797,-0.3265940252928932,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,0.5366787829519797,-0.8287924672030076,1.623176179314646,0.030894617027511038,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,-0.098122333905974,0.31734400267200297,-0.098122333905974,0.5055225334229401,1.9718833674139287	3643
Tight junction	13	40	2.244057805941626	0.0248286822970242	P35579,P12814,P35580,P35221,Q7Z406,O43707,Q92797,P31751,Q8N3R9,Q9BX67,Q13813,Q16625,O14936	Processes and pathways	KEGG Pathways	msigdb_kegg	280,308,222,534,300,325,149,364,148,488,315,541,436	436,1074,325,1613,1289,2057,3023,841,308,1147,1968,2429,592,364,534,708,280,222,2347,1633,1723,1636,1637,1025,3165,2938,1029,315,1402,1166,541,300,148,149,2614,488,1199,2037,2404,1951	0.7224199472328477,0.2224334357534765,0.9366227945511973,-0.0012581004565036626,0.12695555655645674,-0.16304347134508207,-0.6257295573052645,0.34885740302862467,0.9670119136618348,0.19067127264620573,-0.13054795621506413,-0.29373844618932715,0.5366787829519797,0.845141841466991,0.5988184783374502,0.44303477605405855,1.027635769907882,1.2083001127798034,-0.2609563355332265,-0.0012581004565036626,-0.03347806686168351,-0.0012581004565036626,-0.0012581004565036626,0.25413257026133235,-0.726880811724572,-0.5587053640309138,0.25413257026133235,0.9670119136618348,0.09500082791205905,0.19067127264620573,0.5988184783374502,0.9973494401983068,1.5644560394229112,1.5644560394229112,-0.3595238272390506,0.6607309570482511,0.19067127264620573,-0.13054795621506413,-0.2609563355332265,-0.098122333905974	3643
Transmembrane transport	67	254	2.24170455006228	0.0249804736221912	Q9BSK2,Q86VD7,Q8WTV0,O96008,Q07820,Q6NT16,Q15629,O43772,Q8IXU6,Q01650,Q96H78,Q7L0J3,Q9HC07,O75298,Q99442,O75027,P39210,Q9HC21,Q7KZN9,P05067,Q16625,P46939,Q9UHG3,P11166,P21796,Q8N4V1,O95563,Q70HW3,P22466,Q06481,Q9NWR8,Q9UBX3,Q9BQT8,P53985,Q8TB61,O95831,Q96GC9,P16615,O14678,O75251,Q8NHS3,Q9HD20,P30825,O43865,Q6P4Q7,Q9BPX6,P00403,P20674,P55011,P23786,P00846,P45880,O43707,P51790,O75964,P51798,P41440,P11274,Q9NRA0,Q9Y6M7,Q13423,Q9H4I9,Q99523,P25705,P31751,O75844,Q8IYU8	Processes and pathways	GO Biological process	msigdb_gobp	260,256,8,500,506,10,509,13,12,143,274,17,405,393,547,21,267,553,286,29,541,281,430,279,34,167,152,285,38,39,305,306,577,44,573,47,574,172,176,294,52,183,54,55,316,320,559,561,440,200,74,78,325,459,214,460,90,338,227,361,352,244,114,237,364,248,257	2751,1207,2321,3065,646,2408,2047,176,2793,1954,1003,1283,325,13,2754,55,1534,2795,2219,21,2646,294,393,1368,3483,2137,1450,248,3068,1218,214,1698,1372,152,2053,47,500,2705,559,74,2967,703,1962,2054,3149,29,1873,3218,2141,1012,3191,3151,3106,1374,704,1618,1144,3572,1291,3256,279,338,840,2331,1145,2223,172,3406,3544,2427,1015,561,2061,3422,2337,34,38,2517,200,3112,237,563,3073,3196,1622,2341,3424,54,592,364,1713,1224,2342,3486,1226,1624,847,2661,267,90,78,281,1298,3487,795,2519,3264,1802,1155,459,3607,460,1721,2073,44,2159,3075,440,711,2522,3159,3346,2434,2587,2807,1986,2436,799,1477,2812,3079,143,2771,1028,2593,1815,39,955,506,2772,1398,352,2672,3328,959,624,1317,963,1166,1649,509,662,1097,3501,541,2000,3042,2274,10,2366,3456,719,316,2822,1910,285,286,17,256,2989,1410,2277,1177,1108,12,257,671,167,1501,2949,3525,52,573,1502,2734,2829,8,2468,2103,3634,3616,574,274,2833,2906,2907,1674,547,3177,114,682,3235,2737,2292,320,3505,577,260,3334,2840,984,2841,2115,3479,733,1350,3533,244,1057,3058,405,553,183,822,1844,1193,227,2844,2120,2485,2912,3182,305,1852,306,3463,991,1274,430,2401,924,2308,2788,2959,2043,2205,2567,2640,608,2316,693,694,3315,361	-0.4587663248239629,0.15884550726049723,-0.2609563355332265,-0.6593637349435877,0.47430803058067816,-0.29373844618932715,-0.16304347134508207,1.446478167816503,-0.4920008457387619,-0.13054795621506413,0.25413257026133235,0.12695555655645674,0.9366227945511973,5.243267115697605,-0.4587663248239629,2.6800374279695216,0.030894617027511038,-0.4920008457387619,-0.22824695247054547,4.373525061543824,-0.3925286203228279,0.9973494401983068,0.7838890695289682,0.09500082791205905,-1.209424370050621,-0.19560956934146895,0.06298071889501843,1.118191455601226,-0.6593637349435877,0.15884550726049723,1.2382387072449188,-0.03347806686168351,0.09500082791205905,1.5350292358486646,-0.16304347134508207,3.0119856905575273,0.6298028841948623,-0.42560918711049844,0.5677772700633923,2.371337868662573,-0.5921770650124923,0.44303477605405855,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,3.6353042018995785,-0.098122333905974,-0.7947358122572576,-0.19560956934146895,0.25413257026133235,-0.7607655898218467,-0.726880811724572,-0.6930805097254553,0.09500082791205905,0.44303477605405855,-0.0012581004565036626,0.19067127264620573,-1.6016175956969314,0.12695555655645674,-0.8287924672030076,1.027635769907882,0.9061816816409076,0.34885740302862467,-0.2609563355332265,0.19067127264620573,-0.22824695247054547,1.4760406150941263,-1.0350054838275398,-1.421932600442622,-0.29373844618932715,0.25413257026133235,0.5677772700633923,-0.16304347134508207,-1.069696640684267,-0.2609563355332265,3.528055524230381,3.257840018273795,-0.3265940252928932,1.327766595224347,-0.6930805097254553,1.1482768495977804,0.5677772700633923,-0.6593637349435877,-0.7607655898218467,-0.0012581004565036626,-0.2609563355332265,-1.069696640684267,2.707887319665007,0.5366787829519797,0.845141841466991,-0.03347806686168351,0.15884550726049723,-0.2609563355332265,-1.209424370050621,0.15884550726049723,-0.0012581004565036626,0.34885740302862467,-0.3925286203228279,1.0578712931665288,2.058127752852981,2.286376867508823,1.027635769907882,0.12695555655645674,-1.209424370050621,0.3803099800917596,-0.3265940252928932,-0.8287924672030076,-0.06576592628969985,0.19067127264620573,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.03347806686168351,-0.16304347134508207,3.1215736355280526,-0.19560956934146895,-0.6593637349435877,0.7224199472328477,0.44303477605405855,-0.3265940252928932,-0.726880811724572,-0.931491220478586,-0.29373844618932715,-0.3595238272390506,-0.4920008457387619,-0.13054795621506413,-0.29373844618932715,0.3803099800917596,0.06298071889501843,-0.4920008457387619,-0.6593637349435877,1.5938382520831849,-0.4587663248239629,0.25413257026133235,-0.3595238272390506,-0.06576592628969985,3.257840018273795,0.2857692407025649,0.6298028841948623,-0.4587663248239629,0.09500082791205905,0.8756881681175116,-0.3925286203228279,-0.8971691305719629,0.2857692407025649,0.5055225334229401,0.12695555655645674,0.2857692407025649,0.19067127264620573,-0.0012581004565036626,0.6298028841948623,0.47430803058067816,0.2224334357534765,-1.244601121096576,0.5988184783374502,-0.13054795621506413,-0.6257295573052645,-0.22824695247054547,5.593769792208002,-0.2609563355332265,-1.1393655482262741,0.44303477605405855,0.9670119136618348,-0.4920008457387619,-0.098122333905974,1.027635769907882,1.027635769907882,4.734981990697083,1.08805639508316,-0.5921770650124923,0.09500082791205905,-0.22824695247054547,0.19067127264620573,0.2224334357534765,5.444068869967951,1.08805639508316,0.47430803058067816,1.5055575321040489,0.06298071889501843,-0.5587053640309138,-1.315246174406957,2.818941470146897,0.5677772700633923,0.06298071889501843,-0.42560918711049844,-0.4920008457387619,5.940175937290734,-0.29373844618932715,-0.16304347134508207,-4.5798467158688725,-2.2291720974867153,0.5677772700633923,1.0578712931665288,-0.4920008457387619,-0.525313577596298,-0.525313577596298,-0.0012581004565036626,0.5988184783374502,-0.726880811724572,1.8563207862044178,0.47430803058067816,-0.7947358122572576,-0.42560918711049844,-0.22824695247054547,0.9670119136618348,-1.244601121096576,0.5677772700633923,1.08805639508316,-0.8971691305719629,-0.4920008457387619,0.2857692407025649,-0.4920008457387619,-0.16304347134508207,-1.174345720866778,0.44303477605405855,0.12695555655645674,-1.3507131280591325,1.1482768495977804,0.25413257026133235,-0.6257295573052645,0.7838890695289682,0.5988184783374502,1.4168698692908286,0.3803099800917596,-0.06576592628969985,0.19067127264620573,1.2083001127798034,-0.4920008457387619,-0.16304347134508207,-0.29373844618932715,-0.525313577596298,-0.726880811724572,0.9973494401983068,-0.06576592628969985,0.9973494401983068,-1.1393655482262741,0.2857692407025649,0.15884550726049723,0.7531817696547146,-0.2609563355332265,0.31734400267200297,-0.22824695247054547,-0.4587663248239629,-0.5587053640309138,-0.13054795621506413,-0.19560956934146895,-0.3265940252928932,-0.3595238272390506,0.5366787829519797,-0.22824695247054547,0.47430803058067816,0.47430803058067816,-0.8629365633590367,0.8756881681175116	3643
Glycosidase	9	20	2.241446603636668	0.024997160623237	P16278,O00754,P04066,Q9BTY2,O60476,P10253,O60502,P54802,P06280	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	155,435,228,115,264,266,84,147,153	435,1282,264,84,703,228,153,1013,3538,455,266,155,1383,1623,147,1892,3490,1997,3205,115	0.7224199472328477,0.12695555655645674,1.0578712931665288,2.144013371443563,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-1.3862754857551036,0.6916031594494587,1.0578712931665288,1.5350292358486646,0.09500082791205905,-0.0012581004565036626,1.5644560394229112,-0.098122333905974,-1.209424370050621,-0.13054795621506413,-0.7607655898218467,1.8563207862044178	3643
Neuromuscular junction	6	20	2.240742331075132	0.025042770394114	Q7L0J3,P57105,Q14168,P07196,P05067,P46939	Localization	GO Cellular component	msigdb_gocc	17,238,211,125,29,281	1533,29,3218,125,1377,3257,3406,280,3117,281,238,3079,1398,211,1166,418,1096,17,2898,2619	0.030894617027511038,3.6353042018995785,-0.7947358122572576,1.7400910153055076,0.09500082791205905,-0.8287924672030076,-1.0350054838275398,1.027635769907882,-0.6930805097254553,1.027635769907882,1.1482768495977804,-0.6593637349435877,0.09500082791205905,1.268129085929357,0.19067127264620573,0.7531817696547146,0.2224334357534765,4.734981990697083,-0.525313577596298,-0.3595238272390506	3643
Vitamin transport	7	10	2.237163863371362	0.025275632224436	P11166,Q9H2D1,Q8WTV0,O14678,Q9NPF0,Q9HC21,P41440	Processes and pathways	GO Biological process	msigdb_gobp	279,733,8,176,492,553,90	176,703,279,2342,847,90,8,733,553,492	1.446478167816503,0.44303477605405855,1.027635769907882,-0.2609563355332265,0.34885740302862467,2.058127752852981,5.940175937290734,0.44303477605405855,0.5988184783374502,0.6607309570482511	3643
Overlap between signal transduction pathways contributing to lmna laminopathies	9	15	2.234048856353487	0.0254798585973479	P11802,P48729,P49354,Q9Y2U8,P02545,P42166,O75844,O60725,P35222	Processes and pathways	WikiPathways	msigdb_wp	841,439,229,744,265,793,248,587,708	587,248,265,841,708,793,2344,439,229,1801,849,1232,1816,1689,744	0.5366787829519797,1.118191455601226,1.0578712931665288,0.34885740302862467,0.44303477605405855,0.3803099800917596,-0.2609563355332265,0.7224199472328477,1.1783129469800828,-0.06576592628969985,0.34885740302862467,0.15884550726049723,-0.06576592628969985,-0.0012581004565036626,0.44303477605405855	3643
Interferon gamma signaling	6	14	2.2326114312100387	0.0255745796157034	P19474,O15344,P10321,Q13555,P30511,P29372	Processes and pathways	Reactome Pathways	msigdb_reactome	36,253,532,105,138,438	253,1872,590,532,1794,36,438,138,756,2938,1815,2441,105,1563	1.08805639508316,-0.098122333905974,0.5366787829519797,0.5988184783374502,-0.06576592628969985,3.3662912544280115,0.7224199472328477,1.623176179314646,0.4117022638315761,-0.5587053640309138,-0.06576592628969985,-0.29373844618932715,1.943054324684516,0.030894617027511038	3643
Cell activation involved in immune response	14	42	2.230780080250621	0.0256957000570057	Q92538,Q9UQ84,Q15046,Q96FV9,P51809,P02786,P30511,Q9NQT5,P11274,O95219,P00813,Q9NRA0,O96028,P05067	Processes and pathways	GO Biological process	msigdb_gobp	515,33,566,681,476,409,138,638,338,235,56,227,87,29	1207,2860,1217,235,87,56,409,2508,1288,29,1081,653,3256,338,1082,3591,3513,1084,138,1296,1086,1548,476,1553,1233,1893,1727,2526,566,2532,2535,969,1737,515,681,914,1928,638,227,3098,1855,33	0.15884550726049723,-0.525313577596298,0.15884550726049723,1.1482768495977804,2.11542427763213,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.12695555655645674,3.6353042018995785,0.2224334357534765,0.47430803058067816,-0.8287924672030076,0.9061816816409076,0.2224334357534765,-1.7470088834303552,-1.2798752825252815,0.2224334357534765,1.623176179314646,0.12695555655645674,0.2224334357534765,0.030894617027511038,0.6607309570482511,0.030894617027511038,0.15884550726049723,-0.098122333905974,-0.03347806686168351,-0.3265940252928932,0.5677772700633923,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.6298028841948623,0.47430803058067816,0.31734400267200297,-0.098122333905974,0.5055225334229401,1.2083001127798034,-0.6593637349435877,-0.06576592628969985,3.6085359292973544	3643
Postural tremor	8	21	2.2285650280589806	0.0258428601194995	Q9NR77,P03886,P20700,Q14108,O75569,P00846,O75306,O14773	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,62,310,255,350,74,471,391	391,1210,471,350,791,1782,2705,74,62,2967,2654,310,754,1387,955,255,3177,2112,579,32,2562	0.7838890695289682,0.15884550726049723,0.6607309570482511,0.8756881681175116,0.3803099800917596,-0.06576592628969985,-0.42560918711049844,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.3925286203228279,0.9670119136618348,0.4117022638315761,0.09500082791205905,0.2857692407025649,1.08805639508316,-0.726880811724572,-0.16304347134508207,0.5677772700633923,3.6085359292973544,-0.3265940252928932	3643
Abnormality of the shoulder girdle musculature	11	38	2.2269735552696504	0.0259490412279244	P07602,Q9Y487,Q8TD16,Q7LG56,Q14331,P02545,P06753,Q9H9S5,Q96RR1,Q13049,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	69,43,272,464,477,265,394,347,319,188,125	2210,1605,1000,2502,529,1005,2136,3404,2412,265,394,125,69,3257,2331,2337,890,2432,849,2242,2349,1815,2358,188,959,477,464,272,976,319,1581,347,1064,2490,43,1604,1068,1069	-0.22824695247054547,-0.0012581004565036626,0.25413257026133235,-0.3265940252928932,0.5988184783374502,0.25413257026133235,-0.19560956934146895,-1.0350054838275398,-0.29373844618932715,1.0578712931665288,0.7838890695289682,1.7400910153055076,2.427791890653298,-0.8287924672030076,-0.2609563355332265,-0.2609563355332265,0.31734400267200297,-0.29373844618932715,0.34885740302862467,-0.22824695247054547,-0.2609563355332265,-0.06576592628969985,-0.2609563355332265,1.387215394486587,0.2857692407025649,0.6607309570482511,0.6916031594494587,1.0578712931665288,0.2857692407025649,0.9670119136618348,0.030894617027511038,0.9061816816409076,0.25413257026133235,-0.29373844618932715,3.2306497156014906,0.030894617027511038,0.25413257026133235,0.25413257026133235	3643
Intermediate filament protein, conserved site [IPR018039]	6	8	2.2264216745267045	0.0259859500108001	P07197,P20700,P08670,Q03252,P02545,P07196	Sequence	InterPro Conserved site	interpro_conserved_site	221,310,104,207,265,125	265,125,221,104,310,757,207,510	1.0578712931665288,1.7400910153055076,1.2083001127798034,1.943054324684516,0.9670119136618348,0.4117022638315761,1.2979715997804608,0.6298028841948623	3643
Intermediate filament, rod domain [IPR039008]	6	8	2.2264216745267045	0.0259859500108001	P07197,P20700,P08670,Q03252,P02545,P07196	Sequence	InterPro Domain	interpro_domain	221,310,104,207,265,125	265,125,221,104,310,757,207,510	1.0578712931665288,1.7400910153055076,1.2083001127798034,1.943054324684516,0.9670119136618348,0.4117022638315761,1.2979715997804608,0.6298028841948623	3643
Positive regulation of immune response	22	82	2.224550059881972	0.0261114583664701	P46379,P49770,P30511,Q06481,Q9BY67,P02786,Q7Z434,P00813,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,P26583,P23246	Processes and pathways	GO Biological process	msigdb_gobp	3,618,138,39,304,409,420,56,437,566,567,83,590,87,586,227,102,476,638,235,616,375	2050,586,2502,2860,2794,1698,1616,235,87,56,1872,409,2508,590,1789,1081,3256,1704,1082,83,1146,941,1084,2427,375,437,616,3197,138,2229,3297,1547,890,1548,3117,3,618,3344,476,3160,3118,1390,2938,39,1310,623,1394,1395,1727,2526,1645,1479,1818,566,567,1037,1404,2535,969,420,1111,1923,914,1339,1261,1928,1506,3177,3235,919,304,3533,638,2743,227,989,102,828,3245,3098,2308,2788	-0.16304347134508207,0.5366787829519797,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,-0.03347806686168351,-0.0012581004565036626,1.1482768495977804,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.06576592628969985,0.2224334357534765,-0.8287924672030076,-0.03347806686168351,0.2224334357534765,2.172563346869744,0.19067127264620573,0.2857692407025649,0.2224334357534765,-0.29373844618932715,0.8145422833591529,0.7224199472328477,0.5055225334229401,-0.7607655898218467,1.623176179314646,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,0.31734400267200297,0.030894617027511038,-0.6930805097254553,7.00443820279511,0.5055225334229401,-0.931491220478586,0.6607309570482511,-0.726880811724572,-0.6930805097254553,0.09500082791205905,-0.5587053640309138,3.257840018273795,0.12695555655645674,0.5055225334229401,0.09500082791205905,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.0012581004565036626,0.06298071889501843,-0.06576592628969985,0.5677772700633923,0.5677772700633923,0.25413257026133235,0.09500082791205905,-0.3265940252928932,0.2857692407025649,0.7531817696547146,0.2224334357534765,-0.098122333905974,0.31734400267200297,0.12695555655645674,0.15884550726049723,-0.098122333905974,0.06298071889501843,-0.726880811724572,-0.7947358122572576,0.31734400267200297,0.9973494401983068,-1.3507131280591325,0.5055225334229401,-0.42560918711049844,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.3803099800917596,-0.7947358122572576,-0.6593637349435877,-0.22824695247054547,-0.4587663248239629	3643
Mitochondrial carrier domain superfamily [IPR023395]	10	24	2.2244726492984945	0.0261166606973624	Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9	Sequence	InterPro Superfamily	interpro_homologous_superfamily	260,256,285,306,274,577,13,553,693,695	13,2754,1450,1873,2331,1145,2073,2812,2771,2274,2366,285,256,1502,274,577,260,733,553,1064,306,924,693,695	5.243267115697605,-0.4587663248239629,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.19067127264620573,-0.16304347134508207,-0.4920008457387619,-0.4587663248239629,-0.22824695247054547,-0.2609563355332265,1.027635769907882,1.08805639508316,0.06298071889501843,1.0578712931665288,0.5677772700633923,1.08805639508316,0.44303477605405855,0.5988184783374502,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.47430803058067816	3643
Mitochondrial substrate/solute carrier [IPR018108]	10	24	2.2244726492984945	0.0261166606973624	Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9	Sequence	InterPro Repeat	interpro_repeat	260,256,285,306,274,577,13,553,693,695	13,2754,1450,1873,2331,1145,2073,2812,2771,2274,2366,285,256,1502,274,577,260,733,553,1064,306,924,693,695	5.243267115697605,-0.4587663248239629,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.19067127264620573,-0.16304347134508207,-0.4920008457387619,-0.4587663248239629,-0.22824695247054547,-0.2609563355332265,1.027635769907882,1.08805639508316,0.06298071889501843,1.0578712931665288,0.5677772700633923,1.08805639508316,0.44303477605405855,0.5988184783374502,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.47430803058067816	3643
SLC25 family of mitochondrial transporters	10	24	2.2244726492984945	0.0261166606973624	Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9	Drugs and Diseases	Pharos Drug Target Ontology	pharos_dto	260,256,285,306,274,577,13,553,693,695	13,2754,1450,1873,2331,1145,2073,2812,2771,2274,2366,285,256,1502,274,577,260,733,553,1064,306,924,693,695	5.243267115697605,-0.4587663248239629,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.19067127264620573,-0.16304347134508207,-0.4920008457387619,-0.4587663248239629,-0.22824695247054547,-0.2609563355332265,1.027635769907882,1.08805639508316,0.06298071889501843,1.0578712931665288,0.5677772700633923,1.08805639508316,0.44303477605405855,0.5988184783374502,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.47430803058067816	3643
Regulation of immune response	34	136	2.2164547358380404	0.0266603745870832	Q07666,P23246,P46379,P30511,Q5KU26,P14373,Q8TCT8,P19474,Q06481,Q9BY67,P28070,P02786,Q7Z434,Q9NPR9,P00813,O43657,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,P41440,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NZ08,Q9NQT5,O95219,O75955,P26583,P49770	Processes and pathways	GO Biological process	msigdb_gobp	623,375,3,138,396,395,158,36,39,304,164,409,420,48,56,557,437,566,567,83,590,87,586,90,338,227,102,476,245,638,235,249,616,618	1952,1209,2050,586,1695,2501,2502,557,2860,2794,2796,3216,249,1698,1616,235,87,56,1872,409,2508,590,1789,1457,1081,653,2511,3256,1704,338,1082,83,1146,395,941,1084,1794,2427,36,375,437,2762,616,164,3197,138,3520,2229,3297,1547,90,890,1548,2712,3117,3,618,3344,476,3626,797,3160,3118,2436,1390,3038,2938,1815,39,1310,623,1394,1395,1727,2526,1645,1479,2814,1818,1315,1563,566,567,1037,2532,1404,1097,856,3579,396,2535,969,2455,1737,420,3530,2828,158,1111,2100,1923,681,914,1339,2621,1261,1928,863,1506,3177,3235,919,304,1755,3533,48,1847,638,2743,227,989,102,1356,245,828,784,1358,3245,3184,3098,2308,2788,2043,1692,1132,2496	-0.13054795621506413,0.15884550726049723,-0.16304347134508207,0.5366787829519797,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,0.5677772700633923,-0.525313577596298,-0.4920008457387619,-0.4920008457387619,-0.7947358122572576,1.118191455601226,-0.03347806686168351,-0.0012581004565036626,1.1482768495977804,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.06576592628969985,0.06298071889501843,0.2224334357534765,0.47430803058067816,-0.3265940252928932,-0.8287924672030076,-0.03347806686168351,0.9061816816409076,0.2224334357534765,2.172563346869744,0.19067127264620573,0.7838890695289682,0.2857692407025649,0.2224334357534765,-0.06576592628969985,-0.29373844618932715,3.3662912544280115,0.8145422833591529,0.7224199472328477,-0.4587663248239629,0.5055225334229401,1.5055575321040489,-0.7607655898218467,1.623176179314646,-1.315246174406957,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,2.058127752852981,0.31734400267200297,0.030894617027511038,-0.42560918711049844,-0.6930805097254553,7.00443820279511,0.5055225334229401,-0.931491220478586,0.6607309570482511,-2.919565762049335,0.3803099800917596,-0.726880811724572,-0.6930805097254553,-0.29373844618932715,0.09500082791205905,-0.6257295573052645,-0.5587053640309138,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.5055225334229401,0.09500082791205905,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.0012581004565036626,0.06298071889501843,-0.4920008457387619,-0.06576592628969985,0.12695555655645674,0.030894617027511038,0.5677772700633923,0.5677772700633923,0.25413257026133235,-0.3265940252928932,0.09500082791205905,0.2224334357534765,0.34885740302862467,-1.63783022894056,0.7838890695289682,-0.3265940252928932,0.2857692407025649,-0.29373844618932715,-0.03347806686168351,0.7531817696547146,-1.3507131280591325,-0.4920008457387619,1.5350292358486646,0.2224334357534765,-0.16304347134508207,-0.098122333905974,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.3595238272390506,0.15884550726049723,-0.098122333905974,0.34885740302862467,0.06298071889501843,-0.726880811724572,-0.7947358122572576,0.31734400267200297,0.9973494401983068,-0.03347806686168351,-1.3507131280591325,3.0119856905575273,-0.06576592628969985,0.5055225334229401,-0.42560918711049844,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.12695555655645674,1.1482768495977804,0.3803099800917596,0.4117022638315761,0.12695555655645674,-0.7947358122572576,-0.726880811724572,-0.6593637349435877,-0.22824695247054547,-0.4587663248239629,-0.13054795621506413,-0.0012581004565036626,0.2224334357534765,-0.29373844618932715	3643
Clathrin coated vesicle	12	55	2.210708589083223	0.0270560233692866	P11717,Q14108,P20645,P02786,Q9Y5X1,O43493,Q99523,O43752,P42892,O00291,Q5VW38,Q9NUN5	Localization	GO Cellular component	msigdb_gocc	154,255,37,409,107,142,114,454,53,390,23,123	1770,1952,390,834,1444,142,2860,454,1213,1367,2798,2328,3617,409,1702,1703,2144,154,2578,37,53,795,1155,2347,1887,476,2348,2805,2075,3571,2251,952,2257,2596,255,2088,902,3083,23,3355,2180,1050,114,2627,1933,1349,1936,1844,123,3313,2633,3063,1595,107,1525	-0.06576592628969985,-0.13054795621506413,0.7838890695289682,0.34885740302862467,0.06298071889501843,1.5938382520831849,-0.525313577596298,0.6916031594494587,0.15884550726049723,0.09500082791205905,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,0.7531817696547146,-0.03347806686168351,-0.03347806686168351,-0.19560956934146895,1.5350292358486646,-0.3595238272390506,3.284999162596966,2.763483088965262,0.3803099800917596,0.19067127264620573,-0.2609563355332265,-0.098122333905974,0.6607309570482511,-0.2609563355332265,-0.4920008457387619,-0.16304347134508207,-1.5654960467228805,-0.22824695247054547,0.2857692407025649,-0.22824695247054547,-0.3595238272390506,1.08805639508316,-0.16304347134508207,0.31734400267200297,-0.6593637349435877,4.295431147653506,-0.931491220478586,-0.19560956934146895,0.25413257026133235,1.8563207862044178,-0.3595238272390506,-0.098122333905974,0.12695555655645674,-0.098122333905974,-0.06576592628969985,1.7692119702003737,-0.8629365633590367,-0.3595238272390506,-0.6257295573052645,0.030894617027511038,1.943054324684516,0.06298071889501843	3643
Ciliary transition zone	6	11	2.2091341870408603	0.0271653088558785	Q15051,Q15555,O15078,A6NIH7,Q9Y366,Q9UPN4	Localization	GO Cellular component	msigdb_gocc	223,355,194,46,290,388	46,194,3296,2151,1486,223,1243,355,519,388,290	3.0942250631129866,1.3575144142492008,-0.8629365633590367,-0.19560956934146895,0.06298071889501843,1.2083001127798034,0.15884550726049723,0.8756881681175116,0.6298028841948623,0.8145422833591529,1.027635769907882	3643
Impaired pain sensation	11	21	2.208146525807302	0.0272340606237633	Q9NR77,Q13045,O15269,O95714,O95831,O95140,P39210,P07196,P17480,Q14683,Q00796	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	32,507,746,652,47,791,267,125,591,899,156	746,2212,791,1454,652,47,125,591,1878,267,1467,1301,2349,3471,1809,156,507,899,1825,980,32	0.4117022638315761,-0.22824695247054547,0.3803099800917596,0.06298071889501843,0.47430803058067816,3.0119856905575273,1.7400910153055076,0.5366787829519797,-0.098122333905974,1.0578712931665288,0.06298071889501843,0.12695555655645674,-0.2609563355332265,-1.174345720866778,-0.06576592628969985,1.5350292358486646,0.6298028841948623,0.31734400267200297,-0.06576592628969985,0.2857692407025649,3.6085359292973544	3643
Regulation of adaptive immune response	9	24	2.206549457444387	0.0273455513522897	Q9NUQ9,P02786,P30511,Q9NQT5,P14373,P04439,P00813,O15400,O96028	Processes and pathways	GO Biological process	msigdb_gobp	102,409,138,638,395,590,56,586,87	586,2502,87,56,1872,409,2508,590,1081,3256,395,138,1548,2526,1404,2535,969,1737,1923,681,914,1928,638,102	0.5366787829519797,-0.3265940252928932,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,-0.8287924672030076,0.7838890695289682,1.623176179314646,0.030894617027511038,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,0.5055225334229401,1.9718833674139287	3643
Neutrophil degranulation	35	184	2.2055259083939607	0.0274172118039781	P42785,P78371,P84095,P20618,P30519,P14174,Q8N2G8,P10253,P06280,P16278,P11717,O00231,Q8WVQ1,Q07065,O75787,P15586,Q92542,P10619,Q13813,O00754,P07602,O15078,Q13464,Q93050,P12956,Q7L576,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q99436,Q9NQX7	Processes and pathways	Reactome Pathways	msigdb_reactome	4,378,139,137,14,15,398,266,153,155,154,278,423,173,296,410,317,59,315,435,69,194,328,82,83,340,228,103,351,108,115,112,118,121,122	278,3316,932,1135,2322,1209,103,435,611,194,108,1609,118,1534,2700,1078,296,1284,2798,3103,1456,2704,2757,1872,228,2922,2758,590,153,1011,2509,1012,3191,3151,1701,69,3538,2510,1789,455,1457,3528,1081,2222,3435,2511,266,532,59,3219,2144,1964,1082,154,3193,83,1146,2332,1876,3109,15,2868,3468,112,410,3552,155,1965,2869,1084,2577,1620,2426,137,3294,2063,1461,563,3222,3197,3324,14,3407,2709,707,2343,1623,3425,3115,2710,3200,4,709,2432,2935,2237,1300,2156,1229,1805,2241,1632,1806,2349,596,1890,2075,1023,3268,351,1156,3120,1025,2161,2255,378,139,2813,2938,173,1395,2167,2442,2985,1238,2886,328,3473,2528,3348,315,1239,2598,2087,2268,1485,1097,3042,2604,667,2001,340,1106,1741,398,1663,1916,973,423,317,1417,82,482,1835,3092,980,121,1507,2111,3179,683,2293,115,2837,1933,3211,2115,2693,1354,3240,122,2912,2202,1064,1199,3063,2563,2637,2492,1599,2567,1280,609,1860	1.027635769907882,-0.8971691305719629,0.2857692407025649,0.19067127264620573,-0.2609563355332265,0.15884550726049723,1.943054324684516,0.7224199472328477,0.5055225334229401,1.3575144142492008,1.914184390727662,-0.0012581004565036626,1.7982903969638317,0.030894617027511038,-0.42560918711049844,0.2224334357534765,0.9973494401983068,0.12695555655645674,-0.4920008457387619,-0.6930805097254553,0.06298071889501843,-0.42560918711049844,-0.4587663248239629,-0.098122333905974,1.1783129469800828,-0.5587053640309138,-0.4587663248239629,0.5366787829519797,1.5350292358486646,0.25413257026133235,-0.3265940252928932,0.25413257026133235,-0.7607655898218467,-0.726880811724572,-0.03347806686168351,2.427791890653298,-1.3862754857551036,-0.3265940252928932,-0.06576592628969985,0.6916031594494587,0.06298071889501843,-1.3507131280591325,0.2224334357534765,-0.22824695247054547,-1.104482929673742,-0.3265940252928932,1.0578712931665288,0.5988184783374502,2.5402599154147643,-0.7947358122572576,-0.19560956934146895,-0.13054795621506413,0.2224334357534765,1.5350292358486646,-0.7607655898218467,2.172563346869744,0.19067127264620573,-0.2609563355332265,-0.098122333905974,-0.6930805097254553,4.964849362308119,-0.525313577596298,-1.174345720866778,1.8563207862044178,0.7531817696547146,-1.4576838354723742,1.5350292358486646,-0.13054795621506413,-0.525313577596298,0.2224334357534765,-0.3595238272390506,-0.0012581004565036626,-0.29373844618932715,1.623176179314646,-0.8629365633590367,-0.16304347134508207,0.06298071889501843,0.5677772700633923,-0.7947358122572576,-0.7607655898218467,-0.8971691305719629,5.1928477731586264,-1.0350054838275398,-0.42560918711049844,0.44303477605405855,-0.2609563355332265,-0.0012581004565036626,-1.069696640684267,-0.6930805097254553,-0.42560918711049844,-0.7607655898218467,6.233993929662534,0.44303477605405855,-0.29373844618932715,-0.5587053640309138,-0.22824695247054547,0.12695555655645674,-0.19560956934146895,0.15884550726049723,-0.06576592628969985,-0.22824695247054547,-0.0012581004565036626,-0.06576592628969985,-0.2609563355332265,0.5366787829519797,-0.098122333905974,-0.16304347134508207,0.25413257026133235,-0.8287924672030076,0.8756881681175116,0.19067127264620573,-0.6930805097254553,0.25413257026133235,-0.19560956934146895,-0.22824695247054547,0.8145422833591529,1.623176179314646,-0.4920008457387619,-0.5587053640309138,1.4760406150941263,0.09500082791205905,-0.19560956934146895,-0.29373844618932715,-0.5921770650124923,0.15884550726049723,-0.525313577596298,0.9366227945511973,-1.174345720866778,-0.3265940252928932,-0.931491220478586,0.9670119136618348,0.15884550726049723,-0.3595238272390506,-0.16304347134508207,-0.22824695247054547,0.06298071889501843,0.2224334357534765,-0.6257295573052645,-0.3595238272390506,0.47430803058067816,-0.13054795621506413,0.9061816816409076,0.2224334357534765,-0.03347806686168351,0.7838890695289682,-0.0012581004565036626,-0.098122333905974,0.2857692407025649,0.7531817696547146,0.9670119136618348,0.09500082791205905,2.2010744460285183,0.6607309570482511,-0.06576592628969985,-0.6593637349435877,0.2857692407025649,1.7692119702003737,0.06298071889501843,-0.16304347134508207,-0.726880811724572,0.47430803058067816,-0.22824695247054547,1.8563207862044178,-0.4920008457387619,-0.098122333905974,-0.7607655898218467,-0.16304347134508207,-0.3925286203228279,0.12695555655645674,-0.7947358122572576,1.7692119702003737,-0.525313577596298,-0.19560956934146895,0.25413257026133235,0.19067127264620573,-0.6257295573052645,-0.3265940252928932,-0.3595238272390506,-0.29373844618932715,0.030894617027511038,-0.3265940252928932,0.15884550726049723,0.5366787829519797,-0.06576592628969985	3643
Abnormality of the calf	20	71	2.202723097386225	0.0276142712859279	Q7RTS9,Q13126,Q9NR77,P16278,Q8WVQ1,Q8N0X7,Q96L58,O75718,O95831,O00754,Q15056,P08236,O75431,P51798,Q9NX62,Q9NWH9,Q01082,Q96HY6,Q9NUQ7,Q9UIG0	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	11,20,32,155,423,421,303,295,47,435,462,455,213,460,231,371,365,384,524,527	3186,435,1610,2861,2412,499,213,295,3288,1784,652,47,2651,1288,455,3108,155,2145,3406,2337,1710,2147,707,3199,1973,2765,2933,1886,460,1089,365,2257,2258,1893,20,900,462,2887,3302,2728,3304,3413,11,2458,421,1500,3132,2610,423,2612,384,303,728,3575,3001,2195,3096,32,3006,524,3182,371,231,1852,527,2041,2854,2960,1603,1069,693	-0.7607655898218467,0.7224199472328477,-0.0012581004565036626,-0.525313577596298,-0.29373844618932715,0.6298028841948623,1.2382387072449188,0.9973494401983068,-0.8629365633590367,-0.06576592628969985,0.47430803058067816,3.0119856905575273,-0.3925286203228279,0.12695555655645674,0.6916031594494587,-0.6930805097254553,1.5350292358486646,-0.19560956934146895,-1.0350054838275398,-0.2609563355332265,-0.03347806686168351,-0.19560956934146895,0.44303477605405855,-0.7607655898218467,-0.13054795621506413,-0.4587663248239629,-0.5587053640309138,-0.098122333905974,0.6916031594494587,0.2224334357534765,0.845141841466991,-0.22824695247054547,-0.22824695247054547,-0.098122333905974,4.39950530014643,0.31734400267200297,0.6916031594494587,-0.525313577596298,-0.8629365633590367,-0.42560918711049844,-0.8629365633590367,-1.0350054838275398,5.543953911878619,-0.29373844618932715,0.7531817696547146,0.06298071889501843,-0.6930805097254553,-0.3595238272390506,0.7531817696547146,-0.3595238272390506,0.8145422833591529,0.9973494401983068,0.44303477605405855,-1.6016175956969314,-0.5921770650124923,-0.19560956934146895,-0.6593637349435877,3.6085359292973544,-0.5921770650124923,0.6298028841948623,-0.726880811724572,0.845141841466991,1.1783129469800828,-0.06576592628969985,0.6298028841948623,-0.13054795621506413,-0.4920008457387619,-0.5587053640309138,0.030894617027511038,0.25413257026133235,0.47430803058067816	3643
Vascular skin abnormality	29	135	2.200118950727713	0.0277984566739195	P22830,Q14108,Q8IZA0,Q8WVM7,P02545,Q13126,O00192,Q9UBM7,P06280,P16278,P35579,Q8NCH0,Q96L58,Q9Y487,Q96JJ3,Q14739,Q969N2,P10619,P03886,O95155,P00846,P51798,P78536,Q9UQE7,P04066,O75306,Q15437,Q14331,O75844	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	0,255,141,400,265,20,389,289,153,155,280,422,303,43,302,416,318,59,62,307,74,460,216,496,228,471,110,477,248	1281,389,1210,1696,1958,1777,1960,1614,471,3363,248,307,2650,1141,2705,559,74,1872,265,62,2967,703,228,153,2055,1792,59,1377,2512,3108,3552,155,942,3406,2925,1222,2337,1796,2515,0,2658,888,3197,2581,592,1881,708,280,1624,3382,847,2661,1296,1019,2933,3557,794,2236,1885,2583,460,3626,948,2074,2158,1387,797,3571,216,1477,2256,2258,1989,2938,1815,2166,1640,1396,803,20,3328,255,2360,477,899,416,1163,1165,2887,110,1566,2532,541,3273,2944,2775,3371,3475,2366,3456,1250,1909,479,141,1829,1664,422,3517,2011,400,1334,2100,318,3309,302,303,2185,2736,3179,985,3209,2195,1270,737,2399,2956,289,2038,3598,496,2565,3012,1692,43,1604	0.12695555655645674,0.7838890695289682,0.15884550726049723,-0.03347806686168351,-0.13054795621506413,-0.06576592628969985,-0.13054795621506413,-0.0012581004565036626,0.6607309570482511,-0.9659039071751861,1.118191455601226,0.9670119136618348,-0.3925286203228279,0.19067127264620573,-0.42560918711049844,0.5677772700633923,2.371337868662573,-0.098122333905974,1.0578712931665288,2.512197372488192,-0.5921770650124923,0.44303477605405855,1.1783129469800828,1.5350292358486646,-0.16304347134508207,-0.06576592628969985,2.5402599154147643,0.09500082791205905,-0.3265940252928932,-0.6930805097254553,-1.4576838354723742,1.5350292358486646,0.2857692407025649,-1.0350054838275398,-0.5587053640309138,0.15884550726049723,-0.2609563355332265,-0.06576592628969985,-0.3265940252928932,9.72862962082004,-0.3925286203228279,0.31734400267200297,-0.7607655898218467,-0.3595238272390506,0.5366787829519797,-0.098122333905974,0.44303477605405855,1.027635769907882,-0.0012581004565036626,-1.0004082879139022,0.34885740302862467,-0.3925286203228279,0.12695555655645674,0.25413257026133235,-0.5587053640309138,-1.4935285643358234,0.3803099800917596,-0.22824695247054547,-0.098122333905974,-0.3595238272390506,0.6916031594494587,-2.919565762049335,0.2857692407025649,-0.16304347134508207,-0.19560956934146895,0.09500082791205905,0.3803099800917596,-1.5654960467228805,1.2382387072449188,0.06298071889501843,-0.22824695247054547,-0.22824695247054547,-0.13054795621506413,-0.5587053640309138,-0.06576592628969985,-0.19560956934146895,-0.0012581004565036626,0.09500082791205905,0.3803099800917596,4.39950530014643,-0.8971691305719629,1.08805639508316,-0.2609563355332265,0.6607309570482511,0.31734400267200297,0.7531817696547146,0.19067127264620573,0.19067127264620573,-0.525313577596298,1.914184390727662,0.030894617027511038,-0.3265940252928932,0.5988184783374502,-0.8287924672030076,-0.5587053640309138,-0.4587663248239629,-0.9659039071751861,-1.174345720866778,-0.2609563355332265,-1.1393655482262741,0.15884550726049723,-0.098122333905974,0.6607309570482511,1.623176179314646,-0.06576592628969985,-0.0012581004565036626,0.7531817696547146,-1.2798752825252815,-0.13054795621506413,0.7838890695289682,0.12695555655645674,-0.16304347134508207,0.9670119136618348,-0.8629365633590367,0.9973494401983068,0.9973494401983068,-0.19560956934146895,-0.42560918711049844,-0.726880811724572,0.2857692407025649,-0.7607655898218467,-0.19560956934146895,0.15884550726049723,0.44303477605405855,-0.2609563355332265,-0.5587053640309138,1.027635769907882,-0.13054795621506413,-1.8569869502204246,0.6607309570482511,-0.3265940252928932,-0.5921770650124923,-0.0012581004565036626,3.2306497156014906,0.030894617027511038	3643
Abnormality of extrapyramidal motor function	21	80	2.1993777086988984	0.0278510763213213	Q99720,P98175,O96008,P06753,P05067,P16278,P11166,O75787,Q14203,O75251,Q9H6K4,Q9BPX6,Q96RR1,Q6DKK2,P07602,Q15056,Q7LG56,Q9Y4W6,O75569,Q9NWW5,Q9UIG0	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	2,134,500,394,29,155,279,296,415,294,579,320,319,190,69,462,464,608,350,251,527	2499,1610,1078,294,350,296,3363,500,3147,703,29,394,1013,69,3538,1875,279,841,2331,155,591,2869,2925,1222,2225,3113,1713,3199,3153,1225,754,3325,1301,2242,1088,2349,797,1984,1089,134,2080,2721,955,1895,1992,415,3123,963,462,807,190,2893,1827,464,3132,2011,2108,2624,1675,319,3176,3177,2,320,1755,1423,579,2118,3535,251,1431,1064,1521,527,2562,1690,1203,1692,1603,608	-0.3265940252928932,-0.0012581004565036626,0.2224334357534765,0.9973494401983068,0.8756881681175116,0.9973494401983068,-0.9659039071751861,0.6298028841948623,-0.726880811724572,0.44303477605405855,3.6353042018995785,0.7838890695289682,0.25413257026133235,2.427791890653298,-1.3862754857551036,-0.098122333905974,1.027635769907882,0.34885740302862467,-0.2609563355332265,1.5350292358486646,0.5366787829519797,-0.525313577596298,-0.5587053640309138,0.15884550726049723,-0.22824695247054547,-0.6930805097254553,-0.03347806686168351,-0.7607655898218467,-0.726880811724572,0.15884550726049723,0.4117022638315761,-0.8971691305719629,0.12695555655645674,-0.22824695247054547,0.2224334357534765,-0.2609563355332265,0.3803099800917596,-0.13054795621506413,0.2224334357534765,1.6524701228970238,-0.16304347134508207,-0.42560918711049844,0.2857692407025649,-0.098122333905974,-0.13054795621506413,0.7531817696547146,-0.6930805097254553,0.2857692407025649,0.6916031594494587,0.3803099800917596,1.387215394486587,-0.525313577596298,-0.06576592628969985,0.6916031594494587,-0.6930805097254553,-0.13054795621506413,-0.16304347134508207,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,-0.726880811724572,-0.726880811724572,8.21990109917503,0.9670119136618348,-0.03347806686168351,0.09500082791205905,0.5677772700633923,-0.16304347134508207,-1.3507131280591325,1.118191455601226,0.09500082791205905,0.25413257026133235,0.06298071889501843,0.6298028841948623,-0.3265940252928932,-0.0012581004565036626,0.19067127264620573,-0.0012581004565036626,0.030894617027511038,0.5366787829519797	3643
Gait ataxia	21	77	2.198657338738085	0.0279022965533082	Q14108,O15118,O14773,Q9P0J1,Q9NR77,Q5THJ4,Q96RR1,Q5H8A4,P03886,P20700,O00754,P07602,Q8IV08,P00846,Q7LG56,Q03252,Q9Y4W6,P41440,P17480,O43681,P07196	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	255,252,391,689,32,668,319,569,62,310,435,69,73,74,464,207,608,90,591,118,125	1862,435,391,2571,252,2216,118,2503,74,62,2967,2654,125,3151,69,2512,2331,1876,591,2925,1222,2225,310,1798,3028,844,2972,753,1971,2431,1975,90,2713,1885,1301,2238,2242,1387,797,2768,207,955,658,1238,1562,3328,1646,255,899,1565,3124,1404,569,668,2452,1407,464,73,3393,2830,1050,2832,980,2622,319,3210,32,1197,1849,1850,1064,689,1521,2913,1946,2562,608	-0.098122333905974,0.7224199472328477,0.7838890695289682,-0.3595238272390506,1.08805639508316,-0.22824695247054547,1.7982903969638317,-0.3265940252928932,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.3925286203228279,1.7400910153055076,-0.726880811724572,2.427791890653298,-0.3265940252928932,-0.2609563355332265,-0.098122333905974,0.5366787829519797,-0.5587053640309138,0.15884550726049723,-0.22824695247054547,0.9670119136618348,-0.06576592628969985,-0.6257295573052645,0.34885740302862467,-0.5921770650124923,0.4117022638315761,-0.13054795621506413,-0.29373844618932715,-0.13054795621506413,2.058127752852981,-0.42560918711049844,-0.098122333905974,0.12695555655645674,-0.22824695247054547,-0.22824695247054547,0.09500082791205905,0.3803099800917596,-0.4587663248239629,1.2979715997804608,0.2857692407025649,0.47430803058067816,0.15884550726049723,0.030894617027511038,-0.8971691305719629,-0.0012581004565036626,1.08805639508316,0.31734400267200297,0.030894617027511038,-0.6930805097254553,0.09500082791205905,0.5677772700633923,0.47430803058067816,-0.29373844618932715,0.09500082791205905,0.6916031594494587,2.399583395405736,-1.0004082879139022,-0.4920008457387619,0.25413257026133235,-0.4920008457387619,0.2857692407025649,-0.3595238272390506,0.9670119136618348,-0.7607655898218467,3.6085359292973544,0.19067127264620573,-0.06576592628969985,-0.06576592628969985,0.25413257026133235,0.47430803058067816,0.06298071889501843,-0.525313577596298,-0.098122333905974,-0.3265940252928932,0.5366787829519797	3643
Early endosome	35	118	2.197369554975111	0.02799406379251	Q8WUH2,Q9HD42,Q9HC07,Q96C92,P30511,Q96PE3,P14373,Q5VW38,P05067,Q9Y5X2,P11717,Q8N4V1,P10321,Q06481,Q9UIQ6,P02786,Q96L92,Q9Y6W5,Q92542,Q8IV08,P51790,O43752,P61020,P04439,O15400,P41440,Q9H223,Q567U6,Q15075,Q86YV9,Q99523,P31751,O95219,O75955,Q9NWW5	Localization	GO Cellular component	msigdb_gocc	133,276,405,273,138,402,395,23,29,433,154,167,532,39,42,409,575,583,317,73,459,454,596,590,586,90,490,224,354,479,114,364,235,249,251	3141,2321,1606,1774,586,454,1004,1213,588,1078,3361,249,938,235,885,3617,1872,409,2508,590,29,532,3256,154,395,1794,1879,2578,3322,3073,3197,1149,138,3407,364,2229,1019,90,655,1300,459,596,2075,2587,3077,1557,2257,2258,39,801,2596,3473,1030,3348,2361,2530,963,354,2269,1166,224,2093,767,23,1655,1494,2823,810,479,73,167,133,317,1331,3308,2380,2180,273,2621,575,402,2624,114,2687,1676,3056,1931,3237,490,1349,1936,3057,1937,2480,405,276,1193,2912,251,2633,1760,1944,1945,42,3098,3063,3008,2958,3609,3285,2309,1596,1855,2127,3585,433,2407,583	-0.726880811724572,-0.2609563355332265,-0.0012581004565036626,-0.06576592628969985,0.5366787829519797,0.6916031594494587,0.25413257026133235,0.15884550726049723,0.5366787829519797,0.2224334357534765,-0.9659039071751861,1.118191455601226,0.2857692407025649,1.1482768495977804,0.31734400267200297,-2.342454069604444,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,3.6353042018995785,0.5988184783374502,-0.8287924672030076,1.5350292358486646,0.7838890695289682,-0.06576592628969985,-0.098122333905974,-0.3595238272390506,-0.8971691305719629,-0.6593637349435877,-0.7607655898218467,0.19067127264620573,1.623176179314646,-1.0350054838275398,0.845141841466991,-0.22824695247054547,0.25413257026133235,2.058127752852981,0.47430803058067816,0.12695555655645674,0.6916031594494587,0.5366787829519797,-0.16304347134508207,-0.3595238272390506,-0.6593637349435877,0.030894617027511038,-0.22824695247054547,-0.22824695247054547,3.257840018273795,0.3803099800917596,-0.3595238272390506,-1.174345720866778,0.25413257026133235,-0.931491220478586,-0.2609563355332265,-0.3265940252928932,0.2857692407025649,0.8756881681175116,-0.22824695247054547,0.19067127264620573,1.2083001127798034,-0.16304347134508207,0.4117022638315761,4.295431147653506,-0.0012581004565036626,0.06298071889501843,-0.4920008457387619,0.3803099800917596,0.6607309570482511,2.399583395405736,1.5055575321040489,1.6817203809689008,0.9670119136618348,0.12695555655645674,-0.8629365633590367,-0.2609563355332265,-0.19560956934146895,1.0578712931665288,-0.3595238272390506,0.5677772700633923,0.7838890695289682,-0.3595238272390506,1.8563207862044178,-0.3925286203228279,-0.0012581004565036626,-0.6257295573052645,-0.098122333905974,-0.7947358122572576,0.6607309570482511,0.12695555655645674,-0.098122333905974,-0.6257295573052645,-0.098122333905974,-0.29373844618932715,0.7838890695289682,1.0578712931665288,0.19067127264620573,-0.525313577596298,1.118191455601226,-0.3595238272390506,-0.03347806686168351,-0.098122333905974,-0.098122333905974,3.2306497156014906,-0.6593637349435877,-0.6257295573052645,-0.5921770650124923,-0.5587053640309138,-2.042021033479733,-0.8287924672030076,-0.22824695247054547,0.030894617027511038,-0.06576592628969985,-0.16304347134508207,-1.6741333670170677,0.7531817696547146,-0.2609563355332265,0.5677772700633923	3643
Abnormal enchondral ossification	9	30	2.196065086322696	0.0280872851170053	O00116,Q8WVQ1,Q96L58,Q7RTS9,Q14739,P08236,Q96HY6,O96028,Q9UBM7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	374,423,303,11,416,455,384,87,289	374,2412,3483,1372,87,455,1377,2337,1973,847,1464,1802,2434,1562,3328,416,900,1566,2364,11,1500,423,2183,384,303,524,289,2400,3012,693	0.8145422833591529,-0.29373844618932715,-1.209424370050621,0.09500082791205905,2.11542427763213,0.6916031594494587,0.09500082791205905,-0.2609563355332265,-0.13054795621506413,0.34885740302862467,0.06298071889501843,-0.06576592628969985,-0.29373844618932715,0.030894617027511038,-0.8971691305719629,0.7531817696547146,0.31734400267200297,0.030894617027511038,-0.2609563355332265,5.543953911878619,0.06298071889501843,0.7531817696547146,-0.19560956934146895,0.8145422833591529,0.9973494401983068,0.6298028841948623,1.027635769907882,-0.2609563355332265,-0.5921770650124923,0.47430803058067816	3643
Metalloprotease	7	28	2.1957792202924544	0.0281077496826214	P52888,Q9UIQ6,Q9NZ08,O75976,P42892,P78536,P55786	Functions	Protein Atlas Molecular function	protein_atlas_molecular_function	98,42,245,206,53,216,31	1135,1137,2137,248,206,885,2222,3108,2760,53,98,31,216,1042,2776,1322,3133,1188,1264,2737,1422,3554,386,3241,3137,245,42,608	0.19067127264620573,0.19067127264620573,-0.19560956934146895,1.118191455601226,1.2979715997804608,0.31734400267200297,-0.22824695247054547,-0.6930805097254553,-0.4587663248239629,2.763483088965262,1.9718833674139287,3.6085359292973544,1.2382387072449188,0.25413257026133235,-0.4587663248239629,0.12695555655645674,-0.6930805097254553,0.19067127264620573,0.15884550726049723,-0.42560918711049844,0.09500082791205905,-1.4576838354723742,0.8145422833591529,-0.7947358122572576,-0.6930805097254553,1.1482768495977804,3.2306497156014906,0.5366787829519797	3643
Glycoside hydrolase superfamily [IPR017853]	8	16	2.1946227094323425	0.0281906731493033	P16278,P04066,Q9BTY2,P08236,P10253,O60502,P54802,P06280	Sequence	InterPro Superfamily	interpro_homologous_superfamily	155,228,115,455,266,84,147,153	84,703,228,153,1013,3538,704,455,266,155,1623,147,1997,478,115,3002	2.144013371443563,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-1.3862754857551036,0.44303477605405855,0.6916031594494587,1.0578712931665288,1.5350292358486646,-0.0012581004565036626,1.5644560394229112,-0.13054795621506413,0.6607309570482511,1.8563207862044178,-0.5921770650124923	3643
Disproportionate short limb short stature	7	22	2.189929446295508	0.0285293540350264	O00116,Q8WVQ1,Q7RTS9,Q15392,O75718,Q9Y366,Q9UBM7	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	374,423,11,45,295,290,289	374,584,2412,295,3288,1377,2516,1086,2713,1403,416,45,2728,1172,3413,11,1500,423,2183,3001,289,290	0.8145422833591529,0.5366787829519797,-0.29373844618932715,0.9973494401983068,-0.8629365633590367,0.09500082791205905,-0.3265940252928932,0.2224334357534765,-0.42560918711049844,0.09500082791205905,0.7531817696547146,3.1215736355280526,-0.42560918711049844,0.19067127264620573,-1.0350054838275398,5.543953911878619,0.06298071889501843,0.7531817696547146,-0.19560956934146895,-0.5921770650124923,1.027635769907882,1.027635769907882	3643
Enzyme linked receptor protein signaling pathway	25	131	2.1859383657705447	0.0288201148692444	Q8WUH2,Q92896,Q8N3R9,O00291,Q9UQB8,P11717,Q06481,Q9UIQ6,Q8N0X7,Q15375,P43490,Q96TA1,Q9Y4G8,Q96F07,Q13573,Q8N1F7,P78536,Q7L576,P49354,P08670,Q9NWH9,Q99523,Q01082,P31751,P10586	Processes and pathways	GO Biological process	msigdb_gobp	133,136,148,390,26,154,39,42,421,418,71,333,81,344,88,342,216,340,229,104,371,114,365,364,119	2132,390,646,834,2322,788,2793,1606,2049,1774,3101,2502,2700,1367,3404,701,1288,1289,3218,1457,104,1791,119,154,841,2760,3629,2425,1459,1794,2427,3322,3073,3197,592,364,3520,1384,708,2431,1296,71,2712,3117,709,229,2519,1801,1155,2156,3344,3299,2075,2436,1389,1156,1025,216,365,1893,2938,2081,1815,39,1479,1994,2671,88,3225,1484,1163,963,418,2270,2271,1404,1097,1098,3456,419,1827,1909,1910,340,1410,1045,421,342,148,1664,2009,3478,133,2099,2014,2376,136,1833,2378,2103,1049,3332,1923,344,1261,863,333,114,520,2687,3000,2023,984,2026,3238,636,1847,371,42,3098,2562,1855,3138,2855,26,744,2406,1132,81,2407,1443	-0.19560956934146895,0.7838890695289682,0.47430803058067816,0.34885740302862467,-0.2609563355332265,0.3803099800917596,-0.4920008457387619,-0.0012581004565036626,-0.16304347134508207,-0.06576592628969985,-0.6930805097254553,-0.3265940252928932,-0.42560918711049844,0.09500082791205905,-1.0350054838275398,0.44303477605405855,0.12695555655645674,0.12695555655645674,-0.7947358122572576,0.06298071889501843,1.943054324684516,-0.06576592628969985,1.7982903969638317,1.5350292358486646,0.34885740302862467,-0.4587663248239629,-2.997816021189173,-0.29373844618932715,0.06298071889501843,-0.06576592628969985,-0.29373844618932715,-0.8971691305719629,-0.6593637349435877,-0.7607655898218467,0.5366787829519797,0.845141841466991,-1.315246174406957,0.09500082791205905,0.44303477605405855,-0.29373844618932715,0.12695555655645674,2.399583395405736,-0.42560918711049844,-0.6930805097254553,0.44303477605405855,1.1783129469800828,-0.3265940252928932,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.931491220478586,-0.8629365633590367,-0.16304347134508207,-0.29373844618932715,0.09500082791205905,0.19067127264620573,0.25413257026133235,1.2382387072449188,0.845141841466991,-0.098122333905974,-0.5587053640309138,-0.16304347134508207,-0.06576592628969985,3.257840018273795,0.06298071889501843,-0.13054795621506413,-0.3925286203228279,2.11542427763213,-0.7947358122572576,0.06298071889501843,0.19067127264620573,0.2857692407025649,0.7531817696547146,-0.22824695247054547,-0.22824695247054547,0.09500082791205905,0.2224334357534765,0.2224334357534765,-1.1393655482262741,0.7531817696547146,-0.06576592628969985,-0.098122333905974,-0.098122333905974,0.9061816816409076,0.09500082791205905,0.25413257026133235,0.7531817696547146,0.9061816816409076,1.5644560394229112,-0.0012581004565036626,-0.13054795621506413,-1.174345720866778,1.6817203809689008,-0.16304347134508207,-0.13054795621506413,-0.2609563355332265,1.6524701228970238,-0.06576592628969985,-0.2609563355332265,-0.16304347134508207,0.25413257026133235,-0.8971691305719629,-0.098122333905974,0.9061816816409076,0.15884550726049723,0.34885740302862467,0.9366227945511973,1.8563207862044178,0.6298028841948623,-0.3925286203228279,-0.5921770650124923,-0.13054795621506413,0.2857692407025649,-0.13054795621506413,-0.7947358122572576,0.5055225334229401,-0.06576592628969985,0.845141841466991,3.2306497156014906,-0.6593637349435877,-0.3265940252928932,-0.06576592628969985,-0.6930805097254553,-0.4920008457387619,3.9014137223503935,0.44303477605405855,-0.2609563355332265,0.2224334357534765,2.2579809707838456,-0.2609563355332265,0.09500082791205905	3643
Basal part of cell	17	61	2.184375795581073	0.028934645304715	P11166,P42785,Q9BY67,P02786,P53985,Q9NWH9,Q96N67,Q01650,Q14168,P15291,Q6P4Q7,P57105,P30825,O75955,P41440,Q9Y6M7,O14936	Localization	GO Cellular component	msigdb_gocc	279,4,304,409,44,371,401,143,211,112,316,238,54,249,90,361,436	2132,1207,436,1003,3496,249,938,3617,409,2508,1962,2054,3149,3191,704,1457,279,3023,2760,112,941,3552,942,843,1015,2517,501,54,3520,2342,708,889,90,4,44,3075,440,238,3546,2162,143,2259,1029,1727,1398,2267,211,1315,963,662,1041,316,1323,3173,401,863,2292,304,371,361,583	-0.19560956934146895,0.15884550726049723,0.7224199472328477,0.25413257026133235,-1.244601121096576,1.118191455601226,0.2857692407025649,-2.342454069604444,0.7531817696547146,-0.3265940252928932,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.7607655898218467,0.44303477605405855,0.06298071889501843,1.027635769907882,-0.6257295573052645,-0.4587663248239629,1.8563207862044178,0.2857692407025649,-1.4576838354723742,0.2857692407025649,0.34885740302862467,0.25413257026133235,-0.3265940252928932,0.6298028841948623,2.707887319665007,-1.315246174406957,-0.2609563355332265,0.44303477605405855,0.31734400267200297,2.058127752852981,6.233993929662534,3.1215736355280526,-0.6593637349435877,0.7224199472328477,1.1482768495977804,-1.421932600442622,-0.19560956934146895,1.5938382520831849,-0.22824695247054547,0.25413257026133235,-0.03347806686168351,0.09500082791205905,-0.22824695247054547,1.268129085929357,0.12695555655645674,0.2857692407025649,0.47430803058067816,0.25413257026133235,0.9670119136618348,0.12695555655645674,-0.726880811724572,0.7838890695289682,0.34885740302862467,-0.22824695247054547,0.9973494401983068,0.845141841466991,0.8756881681175116,0.5677772700633923	3643
Splenomegaly	24	98	2.1830881080887146	0.0290293221567918	Q14108,O15118,P14174,P02545,P10253,P54802,O00192,P16278,P11166,P28070,Q15392,P15586,Q14739,P00813,O14936,O00754,P07602,P08236,P11274,P04066,P61916,Q9NZ08,Q15437,Q96HY6	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	255,252,15,265,266,147,389,155,279,164,45,410,416,56,436,435,69,455,338,228,351,245,110,384	389,1952,834,435,2792,436,252,1777,1960,2646,748,3363,1141,2757,56,1872,265,703,228,2922,1288,3366,2509,2055,69,455,266,279,3023,2969,338,840,3108,15,410,155,842,1878,2061,2515,2428,2658,164,1622,2659,592,1714,1544,3382,3578,2933,2236,1020,2238,460,2074,2716,147,3408,351,2591,2256,1893,2938,658,803,3473,2672,255,416,45,110,1731,2532,965,541,1905,571,2895,2176,1334,2100,3309,1048,2180,384,2621,2622,1675,1345,2115,1270,2395,2956,245,1064,1852,832	0.7838890695289682,-0.13054795621506413,0.34885740302862467,0.7224199472328477,-0.4920008457387619,0.7224199472328477,1.08805639508316,-0.06576592628969985,-0.13054795621506413,-0.3925286203228279,0.4117022638315761,-0.9659039071751861,0.19067127264620573,-0.4587663248239629,2.6800374279695216,-0.098122333905974,1.0578712931665288,0.44303477605405855,1.1783129469800828,-0.5587053640309138,0.12695555655645674,-0.9659039071751861,-0.3265940252928932,-0.16304347134508207,2.427791890653298,0.6916031594494587,1.0578712931665288,1.027635769907882,-0.6257295573052645,-0.5921770650124923,0.9061816816409076,0.34885740302862467,-0.6930805097254553,4.964849362308119,0.7531817696547146,1.5350292358486646,0.34885740302862467,-0.098122333905974,-0.16304347134508207,-0.3265940252928932,-0.29373844618932715,-0.3925286203228279,1.5055575321040489,-0.0012581004565036626,-0.3925286203228279,0.5366787829519797,-0.03347806686168351,0.030894617027511038,-1.0004082879139022,-1.63783022894056,-0.5587053640309138,-0.22824695247054547,0.25413257026133235,-0.22824695247054547,0.6916031594494587,-0.16304347134508207,-0.42560918711049844,1.5644560394229112,-1.0350054838275398,0.8756881681175116,-0.3595238272390506,-0.22824695247054547,-0.098122333905974,-0.5587053640309138,0.47430803058067816,0.3803099800917596,-1.174345720866778,-0.3925286203228279,1.08805639508316,0.7531817696547146,3.1215736355280526,1.914184390727662,-0.03347806686168351,-0.3265940252928932,0.2857692407025649,0.5988184783374502,-0.098122333905974,0.5677772700633923,-0.525313577596298,-0.19560956934146895,0.12695555655645674,-0.16304347134508207,-0.8629365633590367,0.25413257026133235,-0.19560956934146895,0.8145422833591529,-0.3595238272390506,-0.3595238272390506,-0.0012581004565036626,0.12695555655645674,-0.16304347134508207,0.15884550726049723,-0.2609563355332265,-0.5587053640309138,1.1482768495977804,0.25413257026133235,-0.06576592628969985,0.3803099800917596	3643
Abnormal acetabulum morphology	7	24	2.180259029435273	0.029238266202936	P16278,Q8WVQ1,Q96L58,Q7RTS9,O75718,P08236,Q9Y366	Drugs and Diseases	Human Phenotype Ontology	msigdb_hp	155,423,303,11,295,455,290	2321,1952,2412,295,1784,455,155,2765,2352,1989,806,1905,11,1500,423,3231,2180,1112,303,3096,524,2041,290,2316	-0.2609563355332265,-0.13054795621506413,-0.29373844618932715,0.9973494401983068,-0.06576592628969985,0.6916031594494587,1.5350292358486646,-0.4587663248239629,-0.2609563355332265,-0.13054795621506413,0.3803099800917596,-0.098122333905974,5.543953911878619,0.06298071889501843,0.7531817696547146,-0.7947358122572576,-0.19560956934146895,0.2224334357534765,0.9973494401983068,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,1.027635769907882,-0.22824695247054547	3643