term overlap setsize score pval edge type subtype subtype_key edge_idxs ann_idxs ann_vals sig_size Vacuolar lumen 31 63 4.569265035124488 4.894375318587052e-06 Q8IV08,O14773,P16278,Q14108,P04066,P07437,P50897,Q9H7Z7,P54802,P06865,P06280,P15586,Q9NZJ7,P68371,P07602,P61916,P13473,Q8NHP8,O00584,Q9UMR5,Q99538,P11117,P10253,Q92820,P17900,P53634,P10619,Q13510,P04062,Q9BTY2,P38435 Localization GO Cellular component msigdb_gocc 262,264,11,14,400,401,19,427,166,293,298,310,191,320,72,457,204,79,337,215,346,94,102,364,234,487,127,116,122,250,255 337,2086,264,619,1787,122,400,298,293,1988,401,72,726,1063,102,127,94,2354,1064,204,2891,310,11,234,2453,1136,2609,255,582,945,2546,19,2968,1455,487,993,166,2969,2505,457,320,1459,2462,949,116,14,1913,262,2593,79,364,1050,2481,2022,346,503,250,1307,427,2295,191,215,2665 1.1013384647454063,-0.37059222129993374,1.3648314259575298,0.6038310370230041,-0.21241421080737602,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,-0.31690808027229783,0.9575234066599015,2.5672903217950718,0.46730587199900714,0.21533758545793177,2.2900460179099036,2.0857311239846426,2.3335547149498175,-0.5377405503528547,0.21533758545793177,1.5630573692038123,-1.034071137875609,1.1925614229636166,3.418959561273887,1.446271558144171,-0.5955921179420027,0.17094088359372295,-0.7146987125093559,1.392310058750564,0.6601866548649779,0.30200233977580343,-0.6545664545020534,3.2108682288698214,-1.1713430341599453,-0.014190283332690111,0.8045775073895869,0.259018664523886,1.7791593908234755,-1.1713430341599453,-0.6249367779380635,0.8566305867164241,1.1473959441543768,-0.014190283332690111,-0.5955921179420027,0.30200233977580343,2.1998773817605315,3.309160878702859,-0.26419124276665046,1.3786129091151909,-0.6844855875507391,2.4979505993683864,1.0384916258428032,0.23726642403703146,-0.5955921179420027,-0.31690808027229783,1.0857828718447309,0.7869794546562088,1.4059236947909328,0.07992440556882748,0.9243562959106226,-0.4809780479553145,1.6497305064842487,1.5376396248754793,-0.7452104629394918 3193 Lysosome 36 49 4.529544204673456 5.911106654155063e-06 Q9Y2T2,P20645,Q93050,O14773,P16278,Q14108,P04066,P50897,P56377,P54802,P06865,P06280,P15586,P11279,P11717,Q9NZJ7,Q9Y487,P07602,P38571,P61916,P13473,Q8NCC3,Q9UMR5,P61421,Q99538,P11117,P10253,Q15904,O75503,P53634,P17900,O43681,Q9UBR2,Q13510,P04062,P10619 Processes and pathways KEGG Pathways msigdb_kegg 258,633,138,264,11,14,400,19,545,166,293,298,310,309,568,191,71,72,582,457,204,80,215,466,346,94,102,230,104,487,234,619,244,116,122,127 1313,2086,1274,264,858,619,1705,104,122,400,298,293,72,726,1990,102,127,94,309,568,204,2891,310,11,234,633,582,19,487,166,545,466,457,1625,1910,116,14,230,80,138,346,666,191,244,1980,1603,215,258,71 0.0566926794738131,-0.37059222129993374,0.07992440556882748,1.3648314259575298,0.36520852896444506,0.6038310370230041,-0.16155054834083413,2.2812210779922095,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,-0.31690808027229783,2.2900460179099036,2.0857311239846426,2.3335547149498175,1.1925614229636166,0.6786968138424812,1.5630573692038123,-1.034071137875609,1.1925614229636166,3.418959561273887,1.446271558144171,0.5847653265563068,0.6601866548649779,3.2108682288698214,0.8045775073895869,1.7791593908234755,0.7153141117668748,0.8394016868466264,0.8566305867164241,-0.11157482962869282,-0.26419124276665046,2.1998773817605315,3.309160878702859,1.4595591237186676,2.474223234824225,1.9329933181047383,1.0857828718447309,0.5655565678430635,1.6497305064842487,1.4329036514563958,-0.2904304927178063,-0.08691226787820137,1.5376396248754793,1.392310058750564,2.582335824717171 3193 Secretory granule membrane 25 62 4.390463871903885 1.1310910771777928e-05 O15260,Q93050,Q13576,P27105,O95721,P42785,Q15363,P49755,P11279,P35613,O15126,Q8NF37,O60784,Q9NZJ7,P30519,P07602,Q969Q5,Q92542,P13473,Q5T9A4,Q07065,P10253,Q8TAD4,Q9NQX7,O00264 Localization GO Cellular component msigdb_gocc 259,138,135,137,399,18,29,417,309,317,436,318,192,191,69,72,330,329,204,356,229,102,105,106,371 2345,371,436,259,2264,192,2308,1193,620,2764,399,1497,72,102,455,309,568,204,2229,1447,137,69,3043,1998,317,1896,18,1323,417,2047,1287,1360,2504,1666,637,1247,1624,2238,229,835,778,135,872,1080,29,1762,356,784,318,1175,105,329,138,330,2564,666,1973,880,106,191,2256,1162 -0.5377405503528547,1.006432544850282,0.8907287812193003,1.3786129091151909,-0.4809780479553145,1.6375613175769943,-0.5092252179873332,0.12580968009238108,0.6038310370230041,-0.8703399800828923,0.9575234066599015,-0.03822288271037234,2.5672903217950718,2.2900460179099036,0.8566305867164241,1.1925614229636166,0.6786968138424812,1.5630573692038123,-0.4529950413267082,-0.014190283332690111,1.9329933181047383,2.589810382359061,-1.3514355919674153,-0.31690808027229783,1.162548846164761,-0.26419124276665046,3.226034750624375,0.0566926794738131,0.9243562959106226,-0.3436274762646461,0.07992440556882748,0.03326476765043723,-0.6249367779380635,-0.13645324700708894,0.5847653265563068,0.10296255264400622,-0.11157482962869282,-0.4529950413267082,1.4595591237186676,0.38594722827302785,0.42694183408394704,1.9435485068003742,0.36520852896444506,0.21533758545793177,3.078186020550252,-0.18686982059176915,1.0543605595517835,0.42694183408394704,1.162548846164761,0.1484683010782358,2.2812210779922095,1.1321439407679112,1.9329933181047383,1.1321439407679112,-0.6545664545020534,0.5655565678430635,-0.2904304927178063,0.36520852896444506,2.263445511133267,1.6497305064842487,-0.4529950413267082,0.17094088359372295 3193 Cation transmembrane transporter activity 33 67 4.376797840876733 1.2043558118790544e-05 Q15043,Q93050,P13073,Q9HC07,Q9HC21,Q7KZN9,Q9UDW1,Q9Y6M7,O95202,O75964,Q9H2J7,Q13423,O43772,P56385,Q9NW15,P16615,Q70HW3,P24539,P47985,Q99808,Q9Y487,Q96ES6,Q9BXP2,P12235,Q9UM00,Q9HD20,P61421,P00403,P05141,Q8TAD4,Q9Y619,Q6P4Q7,O43808 Functions GO Molecular function msigdb_gomf 256,138,136,146,405,150,22,151,155,31,289,161,162,418,168,300,50,181,448,321,71,75,475,338,214,87,466,216,361,105,239,375,505 162,505,2671,31,155,216,712,2449,361,1134,1988,2736,727,752,1790,338,136,300,580,2092,1846,2639,181,1997,1795,1797,1617,2864,448,3131,3156,636,1199,418,466,530,994,1111,1717,161,256,899,375,50,150,876,105,1736,138,75,677,321,475,1973,289,1599,879,146,405,87,168,22,1980,214,71,239,151 1.7905380137060627,0.7692555416447295,-0.7760255732552376,3.0502155042807657,1.8243030426289284,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-0.21241421080737602,1.1013384647454063,1.9329933181047383,1.2368621349000533,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,0.8737391734444331,-1.7850748625508288,-2.0464349065431278,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,0.259018664523886,0.19322985148629535,-0.16155054834083413,1.801854471157927,1.392310058750564,0.3443061993948582,1.006432544850282,2.760120300435202,1.8465093473865353,0.36520852896444506,2.2812210779922095,-0.16155054834083413,1.9329933181047383,2.5291039002629425,0.5462030417796385,1.1473959441543768,0.8394016868466264,-0.2904304927178063,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,1.7791593908234755,3.143317850644801,-0.2904304927178063,1.5376396248754793,2.582335824717171,1.446271558144171,1.8465093473865353 3193 Intrinsic component of organelle membrane 78 124 4.308962665303663 1.6402205109011803e-05 O60830,Q99595,Q9P035,Q92643,O43819,P61619,P17152,Q5XKP0,Q9Y2R0,Q15070,Q13505,Q15629,P20020,O75844,Q9Y282,P42892,Q8WVX9,Q16134,Q8TB61,O60499,Q7L0J3,Q86Y82,Q9NQC3,Q86XL3,Q03518,A0FGR8,P51572,Q6P4A7,Q5J8M3,Q16891,Q14739,O96008,Q9UH99,Q9BUN8,Q96NB2,O95470,Q86YN1,Q8N2H4,P13473,O14925,Q9UM00,Q8TCT9,P04439,Q9Y4P3,Q9NVH1,O43505,P57105,Q15388,Q96A33,P57088,Q9BPX6,Q6ZRP7,Q15125,Q9H3K2,Q9GZY8,Q8IWA4,Q9Y512,Q9NPA0,Q9BUR5,P12235,Q9NZ01,Q16611,Q99442,O15258,O00767,Q9H490,Q9UBM7,Q5SNT2,Q9HC21,Q12981,O15126,Q6UXV4,Q96K12,P10321,O76024,Q9BTV4,Q10471,O43808 Localization GO Cellular component msigdb_gocc 0,3,524,519,514,530,529,549,44,48,51,64,580,81,85,91,614,613,101,103,108,627,113,112,111,617,141,142,661,660,147,651,683,165,677,171,177,182,204,211,214,227,233,253,270,275,276,280,284,282,297,295,294,302,312,328,332,336,335,338,347,355,359,351,360,368,370,393,405,420,436,449,450,455,454,483,489,505 617,912,360,211,858,436,351,275,505,514,103,0,1610,81,1026,454,1316,861,2735,171,651,1497,233,455,338,204,529,580,1945,3087,865,2718,3155,91,2614,1853,1287,141,2409,282,276,1666,530,994,1111,111,489,420,51,2365,147,1549,48,294,783,280,64,613,355,2417,660,1295,661,393,549,142,449,295,108,1338,112,627,177,328,1375,2160,182,1554,1146,876,101,227,614,519,1683,2163,284,450,677,1971,359,3,297,2120,483,165,335,764,312,302,368,879,2387,405,744,336,113,2808,270,698,347,524,909,2128,370,2179,683,214,85,44,253,1019,332,1833 0.6038310370230041,0.32323817115644027,1.0384916258428032,1.5376396248754793,0.36520852896444506,0.8907287812193003,1.0543605595517835,1.3229726085415559,0.7692555416447295,0.7514043268649677,2.2812210779922095,4.042548479567164,-0.11157482962869282,2.4501778760429596,0.23726642403703146,0.8566305867164241,0.0566926794738131,0.36520852896444506,-0.8385853324054076,1.744645033106282,0.5655565678430635,-0.03822288271037234,1.446271558144171,0.8566305867164241,1.1013384647454063,1.5630573692038123,0.7334243460639536,0.6601866548649779,-0.2904304927178063,-1.5028434769808663,0.36520852896444506,-0.8071488815311059,-2.0464349065431278,2.359178009634381,-0.7146987125093559,-0.23818692761586824,0.07992440556882748,1.9223825076951602,-0.5665281275626076,1.2946295225860096,1.3229726085415559,-0.13645324700708894,0.7334243460639536,0.259018664523886,0.19322985148629535,2.2364631467360248,0.8045775073895869,0.9243562959106226,2.746560633651398,-0.5377405503528547,1.8684775279957868,-0.062462590653624604,2.800152733484291,1.2514414118114898,0.42694183408394704,1.3088453672804772,2.62670988147732,0.6227553904440447,1.0543605595517835,-0.5665281275626076,0.5655565678430635,0.07992440556882748,0.5655565678430635,0.9739374379111466,0.7153141117668748,1.9117156067218775,0.8737391734444331,1.2514414118114898,2.245500235348313,0.0566926794738131,2.2364631467360248,0.6038310370230041,1.7095511162040427,1.1321439407679112,0.03326476765043723,-0.39780592754705757,1.6858254775131012,-0.062462590653624604,0.17094088359372295,0.36520852896444506,2.2988294808347165,1.472767115384539,0.6227553904440447,0.7514043268649677,-0.13645324700708894,-0.39780592754705757,1.2946295225860096,0.8737391734444331,0.5462030417796385,-0.2904304927178063,1.0543605595517835,3.6753208773984025,1.2514414118114898,-0.37059222129993374,0.8220511190203319,1.7905380137060627,1.1167917984678513,0.44720170401297976,1.1925614229636166,1.2221896821440608,1.0225160037257737,0.36520852896444506,-0.5377405503528547,0.9575234066599015,0.46730587199900714,1.1167917984678513,2.2364631467360248,-0.902417991440706,1.3509647782580774,0.5267030007716262,1.0857828718447309,0.7514043268649677,0.3443061993948582,-0.37059222129993374,1.0225160037257737,-0.39780592754705757,0.5462030417796385,1.5376396248754793,2.4339675988258307,2.8520707218101506,1.4059236947909328,0.259018664523886,1.1321439407679112,-0.21241421080737602 3193 Inorganic molecular entity transmembrane transporter activity 34 74 4.298625166743611 1.718608366974017e-05 Q15043,P21796,Q93050,P13073,Q9C0H2,P45880,Q9HC07,Q7KZN9,Q9UDW1,Q9Y6M7,Q99797,O95202,O75964,Q9H2J7,Q13423,P56385,Q9NW15,P16615,P24539,Q9UBX3,P51798,P47985,Q9Y487,Q96ES6,Q9BXP2,Q96S66,P12235,Q9UM00,Q9HD20,P00403,P05141,Q8TAD4,Q9Y277,Q6P4Q7 Functions GO Molecular function msigdb_gomf 256,7,138,136,13,15,146,150,22,151,411,155,31,289,161,418,168,300,181,54,184,448,71,75,475,474,338,214,87,216,361,105,247,375 2964,619,2671,31,155,216,712,2449,361,1134,1988,2736,727,752,3092,1790,338,136,300,580,2092,1846,2639,7,181,1997,1795,888,1797,1617,2864,15,448,3131,3156,184,636,1199,418,466,530,994,1111,1717,870,161,256,1921,375,150,876,105,929,1736,138,75,474,411,475,13,1973,289,1599,146,87,168,54,22,1980,214,247,71,2443,151 -1.1713430341599453,0.6038310370230041,-0.7760255732552376,3.0502155042807657,1.8243030426289284,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,1.1013384647454063,1.9329933181047383,1.2368621349000533,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,3.5491802513502524,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,3.285196134499565,0.8737391734444331,-1.7850748625508288,-2.0464349065431278,1.6738619652882785,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,1.801854471157927,1.392310058750564,-0.26419124276665046,1.006432544850282,1.8465093473865353,0.36520852896444506,2.2812210779922095,0.32323817115644027,-0.16155054834083413,1.9329933181047383,2.5291039002629425,0.8394016868466264,0.9409967716069575,0.8394016868466264,3.351325980333631,-0.2904304927178063,1.280324185022697,-0.08691226787820137,1.9009921408923331,2.4176108705977826,1.7791593908234755,2.732890881137026,3.143317850644801,-0.2904304927178063,1.5376396248754793,1.419454626258951,2.582335824717171,-0.5665281275626076,1.8465093473865353 3193 Anion transport 36 71 4.27185883797517 1.9385027951512868e-05 Q15043,P08183,P21796,P28288,Q9C0H2,P45880,Q9HC21,Q9Y6M7,O75915,O75746,Q9UJS0,Q9H2J7,Q9NW15,P53985,Q15907,Q9H2D1,Q14728,Q9UBX3,P30536,Q9UHG3,P51798,Q9NZJ7,Q99808,P07602,Q9BXP2,Q96S66,P12235,P12236,O60831,Q8TB61,P05141,Q9Y619,Q9BQT8,Q7L0J3,Q9Y277,O43808 Processes and pathways GO Biological process msigdb_gobp 256,129,7,515,13,15,405,151,528,527,428,289,168,169,306,47,305,54,58,59,184,191,321,72,475,474,338,217,478,101,361,239,238,108,247,505 2964,2181,1571,619,505,553,478,527,528,1889,361,2351,72,129,727,3092,863,338,217,1710,7,515,58,888,654,15,3156,184,730,169,1854,636,3114,1111,870,835,714,305,814,256,899,306,1921,1112,954,108,101,929,677,474,321,238,475,13,1928,47,289,1599,879,405,1057,168,191,54,59,428,247,2083,239,2443,151 -1.1713430341599453,-0.4252722805882104,-0.08691226787820137,0.6038310370230041,0.7692555416447295,0.6970721128067479,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.26419124276665046,1.0384916258428032,-0.5377405503528547,2.5672903217950718,2.0361169935164405,0.46730587199900714,-1.5417758052175927,0.36520852896444506,1.1013384647454063,1.5248183397306079,-0.16155054834083413,3.5491802513502524,0.7514043268649677,2.6556741514333573,0.3443061993948582,0.5655565678430635,3.285196134499565,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,-0.23818692761586824,0.5847653265563068,-1.661294066844009,0.19322985148629535,0.36520852896444506,0.38594722827302785,0.48725623745593405,1.207423100369303,0.40652433044515934,1.392310058750564,0.3443061993948582,1.207423100369303,-0.26419124276665046,0.19322985148629535,0.30200233977580343,2.245500235348313,2.2988294808347165,0.32323817115644027,0.5462030417796385,0.8394016868466264,1.1473959441543768,1.446271558144171,0.8394016868466264,3.351325980333631,-0.26419124276665046,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,0.9575234066599015,0.23726642403703146,1.7791593908234755,1.6497305064842487,2.732890881137026,2.6556741514333573,0.9243562959106226,1.419454626258951,-0.3436274762646461,1.446271558144171,-0.5665281275626076,1.8465093473865353 3193 SLC superfamily of solute carriers 28 44 4.19644262329192 2.7114011056594837e-05 Q15043,Q9Y6C9,Q9HC07,Q9HC21,Q9Y6M7,O95202,Q9UJS0,Q9H2J7,O43772,P53985,Q9H2V7,Q9H2D1,Q70HW3,Q9UBX3,Q9NZJ7,Q99808,Q9BXP2,P12235,Q9BSK2,P12236,Q8TB61,P05141,Q8TAD4,Q9Y619,Q7L0J3,Q9BQT8,Q8IXU6,O43808 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 256,144,146,405,151,155,428,289,162,169,174,47,50,54,191,321,475,338,212,217,101,361,105,239,108,238,117,505 162,505,527,155,361,727,863,338,217,654,730,169,636,1111,870,256,899,1921,1112,954,50,108,117,105,101,677,321,238,212,475,1973,47,289,174,1599,879,146,405,191,54,428,239,144,151 1.7905380137060627,0.7692555416447295,0.7334243460639536,1.8243030426289284,1.0384916258428032,0.46730587199900714,0.36520852896444506,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.19322985148629535,0.36520852896444506,1.392310058750564,0.3443061993948582,-0.26419124276665046,0.19322985148629535,0.30200233977580343,2.760120300435202,2.245500235348313,2.1906198942531567,2.2812210779922095,2.2988294808347165,0.5462030417796385,1.1473959441543768,1.446271558144171,1.5376396248754793,0.8394016868466264,-0.2904304927178063,2.813285883739657,1.280324185022697,1.7330122185385242,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171,1.9117156067218775,1.8465093473865353 3193 Ion transmembrane transporter activity 46 99 4.183634688287646 2.8688498868723045e-05 Q15043,P21796,Q93050,P13073,Q9C0H2,Q6P4A7,P45880,Q9HC07,Q9HC21,Q9UDW1,Q7KZN9,Q9Y6M7,O95202,Q9UJS0,O75964,Q13423,Q9H2J7,O43772,P56385,Q9NW15,P53985,P16615,Q9H2D1,Q70HW3,Q14728,P24539,Q9UBX3,P51798,P47985,Q99808,Q9Y487,Q96ES6,Q9BXP2,Q96S66,P12235,Q9UM00,Q9HD20,P00403,P12236,Q8TB61,Q8TAD4,Q9Y619,Q9BQT8,P05141,Q9Y277,Q6P4Q7 Functions GO Molecular function msigdb_gomf 256,7,138,136,13,142,15,146,405,22,150,151,155,428,31,161,289,162,418,168,169,300,47,50,305,181,54,184,448,321,71,75,475,474,338,214,87,216,217,101,105,239,238,361,247,375 2964,2181,619,162,505,527,2671,31,155,216,712,2449,361,1134,1988,2736,727,752,3092,1790,863,338,217,136,300,580,2092,1846,2639,7,181,1997,1795,888,1797,1617,2864,654,15,448,3131,3156,184,730,169,636,1199,418,466,530,994,1111,1717,870,161,305,1808,256,899,1921,1112,954,142,375,50,150,876,105,101,929,1736,138,75,677,474,321,238,1054,475,13,1973,47,289,1599,879,146,405,87,168,54,22,1980,428,214,247,71,239,2443,151 -1.1713430341599453,-0.4252722805882104,0.6038310370230041,1.7905380137060627,0.7692555416447295,0.7334243460639536,-0.7760255732552376,3.0502155042807657,1.8243030426289284,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,0.36520852896444506,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,3.5491802513502524,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,0.5655565678430635,3.285196134499565,0.8737391734444331,-1.7850748625508288,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,1.801854471157927,1.207423100369303,-0.21241421080737602,1.392310058750564,0.3443061993948582,-0.26419124276665046,0.19322985148629535,0.30200233977580343,1.9117156067218775,1.006432544850282,2.760120300435202,1.8465093473865353,0.36520852896444506,2.2812210779922095,2.2988294808347165,0.32323817115644027,-0.16155054834083413,1.9329933181047383,2.5291039002629425,0.5462030417796385,0.8394016868466264,1.1473959441543768,1.446271558144171,0.23726642403703146,0.8394016868466264,3.351325980333631,-0.2904304927178063,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,1.7791593908234755,2.732890881137026,3.143317850644801,-0.2904304927178063,0.9243562959106226,1.5376396248754793,1.419454626258951,2.582335824717171,1.446271558144171,-0.5665281275626076,1.8465093473865353 3193 Intrinsic component of endoplasmic reticulum membrane 29 48 4.083696775027148 4.432486187888607e-05 Q9P035,Q92643,P51572,Q96A33,P57088,Q9BUN8,Q12981,Q15125,O95470,Q86YN1,Q15629,P10321,O76024,Q9NPA0,O75844,Q9Y282,Q9UM00,Q9NZ01,Q99442,Q8TCT9,Q8TB61,O00767,Q9H490,P04439,Q03518,Q9NQC3,Q9UBM7,Q86XL3,Q9Y4P3 Localization GO Cellular component msigdb_gocc 524,519,141,284,282,165,420,294,171,177,64,455,454,336,81,85,214,347,359,227,101,360,368,233,111,113,370,112,253 617,360,81,454,171,1497,233,455,3087,865,2718,141,282,530,111,420,2365,1549,294,64,2417,661,1338,112,177,1554,101,227,519,1683,284,1971,359,2120,165,368,744,336,113,347,524,909,2128,370,214,85,253,1833 0.6038310370230041,1.0384916258428032,2.4501778760429596,0.8566305867164241,1.744645033106282,-0.03822288271037234,1.446271558144171,0.8566305867164241,-1.5028434769808663,0.36520852896444506,-0.8071488815311059,1.9223825076951602,1.2946295225860096,0.7334243460639536,2.2364631467360248,0.9243562959106226,-0.5377405503528547,-0.062462590653624604,1.2514414118114898,2.62670988147732,-0.5665281275626076,0.5655565678430635,0.0566926794738131,2.2364631467360248,1.7095511162040427,-0.062462590653624604,2.2988294808347165,1.472767115384539,0.7514043268649677,-0.13645324700708894,1.2946295225860096,-0.2904304927178063,1.0543605595517835,-0.37059222129993374,1.7905380137060627,1.0225160037257737,0.46730587199900714,1.1167917984678513,2.2364631467360248,1.0857828718447309,0.7514043268649677,0.3443061993948582,-0.37059222129993374,1.0225160037257737,1.5376396248754793,2.4339675988258307,1.4059236947909328,-0.21241421080737602 3193 Lysosomal lumen 23 35 4.072281910421821 4.655478399806512e-05 P38435,Q8IV08,O14773,P16278,Q14108,P50897,P54802,P06865,P06280,P15586,Q9NZJ7,P07602,P13473,Q8NHP8,O00584,Q9UMR5,Q99538,P11117,P10253,P17900,Q13510,P04062,P10619 Localization GO Cellular component msigdb_gocc 255,262,264,11,14,19,166,293,298,310,191,72,204,79,337,215,346,94,102,234,116,122,127 337,2086,264,619,122,400,298,293,72,726,1063,102,127,94,2354,204,2891,310,11,234,255,582,945,19,166,457,116,14,262,2593,79,346,1307,191,215 1.1013384647454063,-0.37059222129993374,1.3648314259575298,0.6038310370230041,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,0.21533758545793177,2.2900460179099036,2.0857311239846426,2.3335547149498175,-0.5377405503528547,1.5630573692038123,-1.034071137875609,1.1925614229636166,3.418959561273887,1.446271558144171,1.392310058750564,0.6601866548649779,0.30200233977580343,3.2108682288698214,1.7791593908234755,0.8566305867164241,2.1998773817605315,3.309160878702859,1.3786129091151909,-0.6844855875507391,2.4979505993683864,1.0857828718447309,0.07992440556882748,1.6497305064842487,1.5376396248754793 3193 er 47 86 4.072244818051817 4.656220052412508e-05 Q9NR31,P61026,Q9Y3E0,Q8TBX8,P51572,Q5J8M3,Q14739,O75915,Q00765,Q15363,Q16850,Q96A33,O96005,P49755,Q12981,Q15125,O95674,O95470,O15269,Q9Y5M8,Q15392,Q8NF37,Q96FZ7,Q8TCJ2,P84085,Q9Y487,Q969Q5,O15173,Q9NPA0,P46977,Q8NHH9,Q9UM00,Q96GC9,O75845,P48449,Q06136,Q9P2W9,Q07065,Q13190,O60499,O00767,Q86UL3,Q99640,Q9NQC3,Q9UKR5,O00264,Q9NTJ5 Localization OpenCell Localization opencell_localization 523,637,396,665,141,661,147,528,546,29,158,284,160,417,420,294,415,171,303,183,63,318,588,587,458,71,330,76,336,206,472,214,220,224,226,99,100,229,354,103,360,492,365,113,115,371,645 371,360,76,303,1060,103,1355,1574,224,528,2496,171,415,160,2036,1787,687,1030,2314,2712,1169,2316,865,1896,206,226,1285,417,1454,141,2969,3059,2270,656,637,713,458,2238,546,99,229,420,354,147,1549,294,29,63,921,1550,158,661,954,3021,492,1554,1146,318,472,665,587,1966,1259,330,1342,284,588,220,365,2120,3142,1429,880,336,113,523,645,909,2256,100,115,214,2885,396,71,183 1.006432544850282,1.0384916258428032,2.5057902110255577,1.207423100369303,0.21533758545793177,2.2812210779922095,0.03326476765043723,-0.08691226787820137,1.4858962903240147,0.7334243460639536,-0.6249367779380635,1.744645033106282,0.9243562959106226,1.8131093029975978,-0.3436274762646461,-0.21241421080737602,0.5267030007716262,0.23726642403703146,-0.5092252179873332,-0.8071488815311059,0.1484683010782358,-0.5092252179873332,0.36520852896444506,-0.26419124276665046,1.5503857345605445,1.4858962903240147,0.07992440556882748,0.9243562959106226,-0.014190283332690111,1.9223825076951602,-1.1713430341599453,-1.3886547156284181,-0.4809780479553145,0.5655565678430635,0.5847653265563068,0.48725623745593405,0.8566305867164241,-0.4529950413267082,0.7153141117668748,2.3075717767503545,1.4595591237186676,0.9243562959106226,1.0543605595517835,1.8684775279957868,-0.062462590653624604,1.2514414118114898,3.078186020550252,2.6339966056994,0.32323817115644027,-0.062462590653624604,1.8243030426289284,0.5655565678430635,0.30200233977580343,-1.2782188724392092,0.8045775073895869,-0.062462590653624604,0.17094088359372295,1.162548846164761,0.8394016868466264,0.5655565678430635,0.6601866548649779,-0.2904304927178063,0.10296255264400622,1.1321439407679112,0.0566926794738131,1.2946295225860096,0.6601866548649779,1.5248183397306079,1.0384916258428032,-0.37059222129993374,-1.8700849622133329,0.009638014956759703,0.36520852896444506,1.1167917984678513,2.2364631467360248,0.7514043268649677,0.5847653265563068,0.3443061993948582,-0.4529950413267082,2.3075717767503545,2.2182584184461103,1.5376396248754793,-1.00064563472387,0.9739374379111466,2.582335824717171,1.6858254775131012 3193 Membrane lipid metabolic process 22 34 4.040463143214468 5.3345748496358425e-05 Q9P035,P16278,Q16880,P04066,P50897,Q8NBX0,Q96G23,P06865,P06280,O95470,O15269,Q99735,Q9NZJ7,P07602,Q8NCC3,Q9NZ01,Q06136,P17900,Q9H490,Q99805,Q13510,P04062 Processes and pathways GO Biological process msigdb_gobp 524,11,273,400,19,21,159,293,298,171,303,442,191,72,80,347,99,234,368,367,116,122 303,1060,800,1166,171,122,400,298,293,72,726,11,234,1847,917,19,99,116,273,1295,21,80,519,1683,159,1971,442,367,368,707,347,191,524,2256 1.207423100369303,0.21533758545793177,0.40652433044515934,0.1484683010782358,1.744645033106282,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,3.418959561273887,1.446271558144171,-0.23818692761586824,0.32323817115644027,3.2108682288698214,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.07992440556882748,3.148622465340775,2.474223234824225,0.7514043268649677,-0.13645324700708894,1.8243030426289284,-0.2904304927178063,0.8907287812193003,1.0225160037257737,1.0225160037257737,0.5070546681307051,1.0857828718447309,1.6497305064842487,0.7514043268649677,-0.4529950413267082 3193 Sphingolipid metabolic process 16 26 4.021463324198009 5.783771432832374e-05 Q9NZJ7,Q06136,P07602,P06865,P06280,P16278,O95470,P17900,Q16880,Q8NCC3,P50897,O15269,Q13510,Q9NZ01,P04062,Q96G23 Processes and pathways GO Biological process msigdb_gobp 191,99,72,293,298,11,171,234,273,80,19,303,116,347,122,159 303,1060,800,171,122,298,293,72,726,11,234,1847,917,19,99,116,273,1295,80,159,367,707,347,191,524,2256 1.207423100369303,0.21533758545793177,0.40652433044515934,1.744645033106282,2.153135324237049,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,3.418959561273887,1.446271558144171,-0.23818692761586824,0.32323817115644027,3.2108682288698214,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.07992440556882748,2.474223234824225,1.8243030426289284,1.0225160037257737,0.5070546681307051,1.0857828718447309,1.6497305064842487,0.7514043268649677,-0.4529950413267082 3193 golgi 30 63 3.959380226534448 7.514451895462848e-05 P53365,Q9UI14,Q9NR31,Q9Y3E0,P61026,O15127,P61923,P61019,P62820,P49755,Q8IZA0,Q15907,Q15437,Q9H2M9,P55735,O15126,Q5VW38,Q9Y487,Q7Z3C6,Q9UM00,Q13190,Q969E2,O15258,Q15904,Q8TAD4,Q8N6H7,P53367,Q8IXU6,Q9Y371,Q9NTJ5 Localization OpenCell Localization opencell_localization 261,525,523,396,637,274,657,656,531,417,173,306,693,577,440,436,68,71,471,214,354,228,351,230,105,500,248,117,512,645 2635,798,2181,1440,436,274,351,2307,2447,2496,1990,1169,989,1847,990,1617,1897,417,261,248,2267,2321,2547,440,656,637,657,531,1625,1906,354,1512,998,693,230,306,68,1633,471,117,173,500,1679,105,1259,1215,228,2020,961,577,1008,523,645,2256,1933,1602,525,214,512,396,1878,71,710 -0.7452104629394918,0.40652433044515934,-0.4252722805882104,-0.014190283332690111,0.8907287812193003,1.3229726085415559,1.0543605595517835,-0.5092252179873332,-0.5955921179420027,-0.6249367779380635,-0.31690808027229783,0.1484683010782358,0.259018664523886,-0.23818692761586824,0.259018664523886,-0.11157482962869282,-0.26419124276665046,0.9243562959106226,1.3786129091151909,1.4059236947909328,-0.4809780479553145,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.5655565678430635,0.5847653265563068,0.5655565678430635,0.7334243460639536,-0.11157482962869282,-0.26419124276665046,1.0543605595517835,-0.03822288271037234,0.259018664523886,0.5267030007716262,1.4595591237186676,1.207423100369303,2.5972531017791676,-0.11157482962869282,0.8394016868466264,2.1906198942531567,1.7330122185385242,0.7869794546562088,-0.13645324700708894,2.2812210779922095,0.10296255264400622,0.12580968009238108,1.472767115384539,-0.31690808027229783,0.30200233977580343,0.6786968138424812,0.259018664523886,0.7514043268649677,0.5847653265563068,-0.4529950413267082,-0.26419124276665046,-0.08691226787820137,0.7514043268649677,1.5376396248754793,0.7692555416447295,0.9739374379111466,-0.23818692761586824,2.582335824717171,0.5070546681307051 3193 Azurophil granule 30 68 3.9336541740778577 8.36641325783205e-05 O15260,P27105,P16278,O95721,P04066,P07437,P42785,Q9H7Z7,O15400,P06865,P06280,P15586,P11279,Q8NF37,Q9NZJ7,O60784,P68371,P07602,Q92542,P61916,P13473,O00584,Q07065,P10253,Q9NQX7,Q92820,P17900,P53634,Q9BTY2,P10619 Localization GO Cellular component msigdb_gocc 259,137,11,399,400,401,18,427,413,293,298,310,309,318,191,192,320,72,329,457,204,337,229,102,106,364,234,487,250,127 2345,337,2086,259,413,619,192,2308,1193,399,1787,400,298,293,1988,401,72,726,102,127,1064,309,204,2891,310,11,234,2453,137,1136,2609,1896,18,2546,2968,2846,2047,1360,1455,487,993,2969,2505,457,320,1459,2462,229,949,1913,784,2593,318,329,364,1050,2481,2022,2564,503,250,1973,427,106,2295,191,2256,2665 -0.5377405503528547,1.1013384647454063,-0.37059222129993374,1.3786129091151909,0.9243562959106226,0.6038310370230041,1.6375613175769943,-0.5092252179873332,0.12580968009238108,0.9575234066599015,-0.21241421080737602,0.9575234066599015,1.2368621349000533,1.2514414118114898,-0.31690808027229783,0.9575234066599015,2.5672903217950718,0.46730587199900714,2.2900460179099036,2.0857311239846426,0.21533758545793177,1.1925614229636166,1.5630573692038123,-1.034071137875609,1.1925614229636166,3.418959561273887,1.446271558144171,-0.5955921179420027,1.9329933181047383,0.17094088359372295,-0.7146987125093559,-0.26419124276665046,3.226034750624375,-0.6545664545020534,-1.1713430341599453,-0.9675653554604676,-0.3436274762646461,0.03326476765043723,-0.014190283332690111,0.8045775073895869,0.259018664523886,-1.1713430341599453,-0.6249367779380635,0.8566305867164241,1.1473959441543768,-0.014190283332690111,-0.5955921179420027,1.4595591237186676,0.30200233977580343,-0.26419124276665046,0.42694183408394704,-0.6844855875507391,1.162548846164761,1.1321439407679112,1.0384916258428032,0.23726642403703146,-0.5955921179420027,-0.31690808027229783,-0.6545664545020534,0.7869794546562088,1.4059236947909328,-0.2904304927178063,0.9243562959106226,2.263445511133267,-0.4809780479553145,1.6497305064842487,-0.4529950413267082,-0.7452104629394918 3193 Lipid localization 31 69 3.891965145364171 9.943553251412496e-05 P08183,P23786,Q9BQE5,O15260,P28288,Q14108,Q14534,Q99720,P35610,O43772,O95674,Q8WTV0,Q9H2V7,P31751,P30536,Q9NZJ7,P09455,Q9H4M9,P07602,P61916,Q14849,Q9BUR5,Q7Z3C6,P35790,Q96GC9,Q9UID3,Q9H6V9,P17900,Q86Y82,P04062,O43808 Processes and pathways GO Biological process msigdb_gobp 129,4,6,259,515,14,403,26,288,162,415,43,174,313,58,191,567,452,72,457,74,335,471,340,220,615,96,234,627,122,505 617,3164,858,259,162,505,1131,1194,1750,415,2036,3084,122,1889,1988,72,726,2186,129,567,863,1710,1615,234,1847,2640,4,515,58,313,1579,888,288,340,1241,1853,457,1952,2197,14,403,74,2328,784,954,471,627,3136,43,220,26,6,2120,335,1429,1738,2385,174,452,96,1389,191,2256,1695,615,824,2979,2259,1833 0.6038310370230041,-2.2317979195120636,0.36520852896444506,1.3786129091151909,1.7905380137060627,0.7692555416447295,0.17094088359372295,0.12580968009238108,-0.18686982059176915,0.9243562959106226,-0.3436274762646461,-1.5028434769808663,2.153135324237049,-0.26419124276665046,-0.31690808027229783,2.5672903217950718,0.46730587199900714,-0.4252722805882104,2.0361169935164405,0.6786968138424812,0.36520852896444506,-0.16155054834083413,-0.11157482962869282,1.446271558144171,-0.23818692761586824,-0.7452104629394918,3.6003046943759847,0.7514043268649677,2.6556741514333573,1.1776036696350574,-0.08691226787820137,0.3443061993948582,1.280324185022697,1.1013384647454063,0.10296255264400622,-0.23818692761586824,0.8566305867164241,-0.2904304927178063,-0.4252722805882104,3.309160878702859,0.9575234066599015,2.536807538431712,-0.5092252179873332,0.42694183408394704,0.30200233977580343,0.8394016868466264,0.6038310370230041,-1.8273246014917721,2.871125247428219,1.5248183397306079,3.0892345539041384,3.5925647235517952,-0.37059222129993374,1.1167917984678513,0.009638014956759703,-0.16155054834083413,-0.5377405503528547,1.7330122185385242,0.8737391734444331,2.324934091671502,0.03326476765043723,1.6497305064842487,-0.4529950413267082,-0.13645324700708894,0.6227553904440447,0.40652433044515934,-1.1713430341599453,-0.4529950413267082,-0.21241421080737602 3193 Sphingolipid metabolism 15 26 3.856428309102701 0.0001150558207214 Q9NZJ7,P51648,Q06136,P07602,P06865,P06280,P16278,O95470,P17900,Q16880,Q13510,Q8NBJ7,P04062,P10619,Q96G23 Processes and pathways Reactome Pathways msigdb_reactome 191,130,99,72,293,298,11,171,234,273,116,56,122,127,159 617,303,1060,619,2496,171,122,298,293,72,726,127,2891,11,234,1847,130,99,116,273,56,159,2120,707,191,2256 0.6038310370230041,1.207423100369303,0.21533758545793177,0.6038310370230041,-0.6249367779380635,1.744645033106282,2.153135324237049,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-1.034071137875609,3.418959561273887,1.446271558144171,-0.23818692761586824,2.015915696016737,2.3075717767503545,2.1998773817605315,1.3370121237135937,2.69120665946763,1.8243030426289284,-0.37059222129993374,0.5070546681307051,1.6497305064842487,-0.4529950413267082 3193 transporter 25 56 3.7895748210637343 0.0001509053544888 O60830,Q99595,Q567V2,Q9Y5L0,Q8TEX9,O15397,P61619,O43772,P53985,O43615,Q9H2V7,Q96P70,Q9H2D1,Q15070,P55735,Q92544,Q9NR77,Q99808,Q8N1F7,P52292,Q9HD45,P55060,Q9Y619,Q99805,Q12769 Functions Panther Protein class panther_protein_class 0,3,5,397,395,526,530,162,169,414,174,435,47,48,440,315,61,321,586,333,90,480,239,367,623 1189,685,1745,1274,2261,526,414,619,162,2637,0,2574,941,1359,2544,654,1241,2002,333,2721,1402,730,169,1854,480,440,1800,530,623,2693,48,5,1921,1730,586,1002,1865,395,315,931,1924,435,845,3,367,321,2522,47,174,1386,90,61,1646,824,397,239 0.12580968009238108,0.5267030007716262,-0.18686982059176915,0.07992440556882748,-0.4809780479553145,0.7334243460639536,0.9243562959106226,0.6038310370230041,1.7905380137060627,-0.7452104629394918,4.042548479567164,-0.6844855875507391,0.30200233977580343,0.03326476765043723,-0.6545664545020534,0.5655565678430635,0.10296255264400622,-0.31690808027229783,1.1167917984678513,-0.8071488815311059,0.009638014956759703,0.46730587199900714,1.7677180561785404,-0.23818692761586824,0.8220511190203319,0.8907287812193003,-0.21241421080737602,0.7334243460639536,0.6038310370230041,-0.7760255732552376,2.800152733484291,3.5925647235517952,-0.26419124276665046,-0.16155054834083413,0.6601866548649779,0.259018664523886,-0.23818692761586824,0.9739374379111466,1.1776036696350574,0.32323817115644027,-0.26419124276665046,0.9076007240012801,0.38594722827302785,3.6753208773984025,1.0225160037257737,1.1473959441543768,-0.6249367779380635,2.813285883739657,1.7330122185385242,0.03326476765043723,2.376064301841973,2.6412527563805264,-0.11157482962869282,0.40652433044515934,0.9739374379111466,1.446271558144171 3193 Transporter activity 74 161 3.786027360033237 0.0001530748280058 O60830,Q8NE01,P08183,Q99595,Q15043,P21796,Q93050,P13073,Q9C0H2,Q6P4A7,P45880,Q9NS69,Q9HC07,Q9HC21,Q9UDW1,Q7KZN9,Q9Y6M7,Q15388,Q99797,O95202,Q9UJS0,O75964,Q13423,O43676,Q9H2J7,O43772,P49755,P56385,Q9NW15,P53985,O75027,Q8WTV0,Q9H2V7,P16615,Q9H2D1,Q70HW3,Q14728,P24539,Q9UBX3,P30536,P51798,P47985,Q99808,Q9Y487,Q9P0J0,Q14849,Q96ES6,P61916,O15173,Q9BXP2,Q96S66,O75306,O14925,P12235,Q9UM00,Q9HD20,Q9BSK2,P00403,P12236,Q7Z3C6,Q96GC9,Q8TB61,Q8TAD4,Q9Y619,Q9BQT8,Q7L0J3,P17900,P05141,Q03518,Q8IXU6,Q9Y277,Q6P4Q7,P04062,P38435 Functions GO Molecular function msigdb_gomf 0,128,129,3,256,7,138,136,13,142,15,16,146,405,22,150,151,280,411,155,428,31,161,34,289,162,417,418,168,169,170,43,174,300,47,50,305,181,54,58,184,448,321,71,201,74,75,457,76,475,474,205,211,338,214,87,212,216,217,471,220,101,105,239,238,108,234,361,111,117,247,375,122,255 912,2134,2964,1234,2181,211,858,76,34,619,162,505,0,170,1443,205,2265,1942,527,2671,31,1316,593,3053,155,2350,651,216,122,712,2449,361,1134,1988,2736,129,727,752,3092,1790,863,338,217,136,300,234,3149,580,2092,1846,2639,7,1847,181,1997,515,3070,58,1795,888,1797,1617,255,2864,654,15,448,3131,1241,417,3152,3156,184,1583,1171,1402,730,169,636,1199,418,466,530,457,994,1111,1717,870,111,161,2414,305,1808,74,256,280,899,2416,1209,1921,1112,954,142,375,50,150,108,471,117,628,128,876,105,101,929,43,1736,138,75,220,677,474,845,3,411,321,2564,238,212,1054,475,1429,1738,13,1973,47,289,174,1599,879,146,405,87,2808,16,168,201,54,22,853,1980,428,214,883,247,71,1703,239,2443,151,649 0.32323817115644027,-0.39780592754705757,-1.1713430341599453,0.10296255264400622,-0.4252722805882104,1.5376396248754793,0.36520852896444506,2.5057902110255577,2.9927281115085713,0.6038310370230041,1.7905380137060627,0.7692555416447295,4.042548479567164,1.744645033106282,-0.014190283332690111,1.5503857345605445,-0.4809780479553145,-0.2904304927178063,0.7334243460639536,-0.7760255732552376,3.0502155042807657,0.0566926794738131,0.6415400506909451,-1.3886547156284181,1.8243030426289284,-0.5377405503528547,0.5655565678430635,1.5248183397306079,2.153135324237049,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,-0.31690808027229783,-0.8385853324054076,2.0361169935164405,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,0.36520852896444506,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,1.446271558144171,-2.0015302332107483,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,3.5491802513502524,-0.23818692761586824,1.6858254775131012,-0.31690808027229783,0.7514043268649677,-1.426290709801661,2.6556741514333573,-0.21241421080737602,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,1.392310058750564,-1.00064563472387,0.5655565678430635,3.285196134499565,0.8737391734444331,-1.7850748625508288,0.10296255264400622,0.9243562959106226,-2.0015302332107483,-2.0464349065431278,1.6738619652882785,-0.08691226787820137,0.1484683010782358,0.009638014956759703,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,0.8566305867164241,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,2.2364631467360248,1.801854471157927,-0.5665281275626076,1.207423100369303,-0.21241421080737602,2.536807538431712,1.392310058750564,1.3088453672804772,0.3443061993948582,-0.5665281275626076,0.12580968009238108,-0.26419124276665046,0.19322985148629535,0.30200233977580343,1.9117156067218775,1.006432544850282,2.760120300435202,1.8465093473865353,2.245500235348313,0.8394016868466264,2.1906198942531567,0.6038310370230041,2.075908277865556,0.36520852896444506,2.2812210779922095,2.2988294808347165,0.32323817115644027,2.871125247428219,-0.16155054834083413,1.9329933181047383,2.5291039002629425,1.5248183397306079,0.5462030417796385,0.8394016868466264,0.38594722827302785,3.6753208773984025,0.9409967716069575,1.1473959441543768,-0.6545664545020534,1.446271558144171,1.5376396248754793,0.23726642403703146,0.8394016868466264,0.009638014956759703,-0.16155054834083413,3.351325980333631,-0.2904304927178063,2.813285883739657,1.280324185022697,1.7330122185385242,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,-0.902417991440706,3.2657379732892013,1.7791593908234755,1.6006322940022837,2.732890881137026,3.143317850644801,0.38594722827302785,-0.2904304927178063,0.9243562959106226,1.5376396248754793,0.36520852896444506,1.419454626258951,2.582335824717171,-0.13645324700708894,1.446271558144171,-0.5665281275626076,1.8465093473865353,0.5847653265563068 3193 Mitochondrial transmembrane transport 24 51 3.745484921744124 0.0001800456613862 O60830,Q99595,P23786,P21796,Q6P4A7,Q8IYU8,Q15388,O95202,Q9UJS0,O75964,O43772,Q9BPX6,P56385,O75027,Q9H2D1,P24539,O95831,P12235,O14925,Q9BSK2,P12236,P05141,Q9Y619,Q9BQT8 Processes and pathways GO Biological process msigdb_gobp 0,3,4,7,142,410,280,155,428,31,162,297,418,170,47,181,194,338,211,212,217,361,239,238 211,414,162,0,170,2788,527,2671,31,1316,155,194,651,361,1134,3129,338,217,7,4,181,1997,1797,3131,1853,730,1199,418,1111,280,2327,557,142,410,2832,876,2594,502,677,3,297,238,212,47,1599,879,2253,428,824,1019,239 1.5376396248754793,0.9243562959106226,1.7905380137060627,4.042548479567164,1.744645033106282,-0.902417991440706,0.7334243460639536,-0.7760255732552376,3.0502155042807657,0.0566926794738131,1.8243030426289284,1.6375613175769943,0.5655565678430635,1.0384916258428032,0.17094088359372295,-1.7850748625508288,1.1013384647454063,1.5248183397306079,3.5491802513502524,3.6003046943759847,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,-1.7850748625508288,-0.23818692761586824,0.46730587199900714,0.12580968009238108,0.9243562959106226,0.19322985148629535,1.3088453672804772,-0.5092252179873332,0.6970721128067479,1.9117156067218775,0.9409967716069575,-0.934824649241834,0.36520852896444506,-0.6844855875507391,0.7869794546562088,0.5462030417796385,3.6753208773984025,1.2514414118114898,1.446271558144171,1.5376396248754793,2.813285883739657,-0.08691226787820137,0.36520852896444506,-0.4529950413267082,0.9243562959106226,0.40652433044515934,0.259018664523886,1.446271558144171 3193 Endoplasmic reticulum golgi intermediate compartment 20 47 3.71551122449513 0.0002027932622452 P24390,O15260,P51572,P80303,Q15363,Q9Y3B3,P49755,Q8N511,Q9BVK6,Q02818,Q9Y6Y8,Q9Y282,Q96GC9,Q13190,Q12907,O15258,Q15904,P53634,Q03518,Q9UBR2 Localization GO Cellular component msigdb_gocc 2,259,141,24,29,30,417,49,444,55,476,85,220,354,490,351,230,487,111,244 798,351,259,604,1574,1652,802,1615,2,3087,867,417,1506,141,2504,487,993,656,24,55,111,490,354,674,2240,29,230,1211,1116,49,1215,1519,1682,220,2025,444,2289,961,1483,1933,244,1696,85,513,30,710,476 0.40652433044515934,1.0543605595517835,1.3786129091151909,0.6227553904440447,-0.08691226787820137,-0.13645324700708894,0.40652433044515934,-0.11157482962869282,3.7462657069794476,-1.5028434769808663,0.36520852896444506,0.9243562959106226,-0.03822288271037234,1.9223825076951602,-0.6249367779380635,0.8045775073895869,0.259018664523886,0.5655565678430635,3.1219129348274657,2.69120665946763,2.2364631467360248,0.8045775073895869,1.0543605595517835,0.5462030417796385,-0.4529950413267082,3.078186020550252,1.4595591237186676,0.12580968009238108,0.19322985148629535,2.7869149799952893,0.12580968009238108,-0.03822288271037234,-0.13645324700708894,1.5248183397306079,-0.31690808027229783,0.8907287812193003,-0.4809780479553145,0.30200233977580343,-0.014190283332690111,-0.26419124276665046,1.4329036514563958,-0.13645324700708894,2.4339675988258307,0.7692555416447295,3.067058131253242,0.5070546681307051,0.8394016868466264 3193 Lytic vacuole organization 9 24 3.710244142190125 0.0002070594683254 P54802,P10253,O75503,Q14108,Q8N511,Q9HC07,P50897,P04062,P11117 Processes and pathways GO Biological process msigdb_gobp 166,102,104,14,49,146,19,122,94 1313,264,104,686,122,726,102,94,409,19,1287,166,1247,1250,14,838,784,49,819,977,146,1389,720,1484 0.0566926794738131,1.3648314259575298,2.2812210779922095,0.5267030007716262,2.153135324237049,0.46730587199900714,2.2900460179099036,2.3335547149498175,0.9409967716069575,3.2108682288698214,0.07992440556882748,1.7791593908234755,0.10296255264400622,0.10296255264400622,3.309160878702859,0.38594722827302785,0.42694183408394704,2.7869149799952893,0.40652433044515934,0.28059656391052684,1.9009921408923331,0.03326476765043723,0.48725623745593405,-0.014190283332690111 3193 Vacuole organization 31 54 3.693921183305837 0.0002208222722803 P53365,O14773,Q9Y2L5,Q8TBX8,Q14108,Q6IAA8,Q15286,Q9HC07,P50897,P50851,P42345,P62820,Q96AX1,Q9H269,P54802,P16615,Q8N511,Q9H2M9,O95295,Q9P253,Q7Z3C6,Q96GC9,P11117,P07686,P10253,O75503,Q16706,Q86Y82,Q9Y371,P04062,Q9UHD9 Processes and pathways GO Biological process msigdb_gobp 261,264,795,665,14,784,783,146,19,655,409,531,819,822,166,300,49,577,686,720,471,220,94,726,102,104,362,627,512,122,379 1313,264,1574,104,2735,686,2907,122,1988,726,102,94,300,1945,409,655,19,1287,261,166,2147,1247,531,1250,14,838,814,783,362,784,471,627,49,665,1259,819,220,2562,977,961,822,577,146,1691,1389,720,379,1484,2218,2259,1700,795,512,1606 0.0566926794738131,1.3648314259575298,-0.08691226787820137,2.2812210779922095,-0.8385853324054076,0.5267030007716262,-1.0678476456651755,2.153135324237049,-0.31690808027229783,0.46730587199900714,2.2900460179099036,2.3335547149498175,1.2368621349000533,-0.2904304927178063,0.9409967716069575,0.5655565678430635,3.2108682288698214,0.07992440556882748,1.3786129091151909,1.7791593908234755,-0.39780592754705757,0.10296255264400622,0.7334243460639536,0.10296255264400622,3.309160878702859,0.38594722827302785,0.40652433044515934,0.42694183408394704,1.0384916258428032,0.42694183408394704,0.8394016868466264,0.6038310370230041,2.7869149799952893,0.5655565678430635,0.10296255264400622,0.40652433044515934,1.5248183397306079,-0.6545664545020534,0.28059656391052684,0.30200233977580343,0.40652433044515934,0.6786968138424812,1.9009921408923331,-0.13645324700708894,0.03326476765043723,0.48725623745593405,1.006432544850282,-0.014190283332690111,-0.4252722805882104,-0.4529950413267082,-0.13645324700708894,0.42694183408394704,0.7692555416447295,-0.08691226787820137 3193 Outer membrane 45 93 3.672455708449983 0.0002402307975439 Q9NZ45,P21796,P50402,P52789,Q9NVH1,P45880,Q9NS69,P09601,Q9Y6C9,Q16891,P57105,Q15388,Q99720,O96008,Q96RL7,P42345,Q9NUQ2,Q5XKP0,Q9NQZ5,Q99623,Q8N4H5,O00165,O43169,Q9NX63,Q9NVT9,Q6NUM9,O60313,Q13505,Q9GZY8,P30536,Q9NZJ7,Q6UXV4,Q8IWA4,Q9Y512,Q9HCL2,Q9BUR5,Q96TC7,Q16611,Q8NBU5,Q9UBM7,Q8WY22,O00264,Q9Y277,Q9Y371,Q8N2A8 Localization GO Cellular component msigdb_gocc 134,7,266,516,270,15,16,17,144,660,276,280,26,651,285,409,682,549,680,678,41,45,46,698,697,301,430,51,312,58,191,449,328,332,208,335,601,355,628,370,114,371,247,512,123 45,371,1098,3164,46,430,1985,1493,1610,1316,2735,1750,651,1787,3105,1841,17,2794,7,58,1579,3155,409,1451,15,266,1853,516,2616,276,2823,1292,51,2511,1811,280,1917,355,660,1295,1813,549,301,1114,449,1764,328,1375,2160,1472,123,41,2373,1174,628,877,114,1819,2163,1052,1596,285,601,2022,678,26,1091,335,1054,764,312,2857,208,1185,792,680,16,682,2026,270,697,1600,698,707,134,191,1602,370,2179,247,512,332,144 2.832792341598909,1.006432544850282,0.19322985148629535,-2.2317979195120636,2.832792341598909,0.9076007240012801,-0.31690808027229783,-0.03822288271037234,-0.11157482962869282,0.0566926794738131,-0.8385853324054076,-0.18686982059176915,0.5655565678430635,-0.21241421080737602,-1.6209927176562446,-0.23818692761586824,3.250973747172662,-0.902417991440706,3.5491802513502524,2.6556741514333573,-0.08691226787820137,-2.0464349065431278,0.9409967716069575,-0.014190283332690111,3.285196134499565,1.3648314259575298,-0.23818692761586824,0.7514043268649677,-0.7146987125093559,1.3229726085415559,-0.934824649241834,0.07992440556882748,2.746560633651398,-0.6249367779380635,-0.21241421080737602,1.3088453672804772,-0.26419124276665046,1.0543605595517835,0.5655565678430635,0.07992440556882748,-0.21241421080737602,0.7153141117668748,1.2221896821440608,0.19322985148629535,0.8737391734444331,-0.18686982059176915,1.1321439407679112,0.03326476765043723,-0.39780592754705757,-0.014190283332690111,2.1436487406837603,2.8899600348937455,-0.5377405503528547,0.1484683010782358,0.6038310370230041,0.36520852896444506,2.2182584184461103,-0.21241421080737602,-0.39780592754705757,0.23726642403703146,-0.08691226787820137,1.2946295225860096,0.6415400506909451,-0.31690808027229783,0.5462030417796385,3.0892345539041384,0.21533758545793177,1.1167917984678513,0.23726642403703146,0.44720170401297976,1.1925614229636166,-0.9675653554604676,1.5503857345605445,0.1484683010782358,0.42694183408394704,0.5462030417796385,3.2657379732892013,0.5462030417796385,-0.31690808027229783,1.3509647782580774,0.5267030007716262,-0.08691226787820137,0.5267030007716262,0.5070546681307051,1.9748849511122126,1.6497305064842487,-0.08691226787820137,1.0225160037257737,-0.39780592754705757,1.419454626258951,0.7692555416447295,1.1321439407679112,1.9117156067218775 3193 Azurophil granule membrane 13 23 3.615040095033685 0.0003003011412441 O60784,Q07065,P10253,O15260,P07602,Q92542,P27105,Q9NQX7,P13473,P42785,P11279,Q8NF37,Q9NZJ7 Localization GO Cellular component msigdb_gocc 192,229,102,259,72,329,137,106,204,18,309,318,191 259,192,2308,1193,399,72,102,309,204,137,1896,18,2047,1360,229,784,318,329,2564,1973,106,191,2256 1.3786129091151909,1.6375613175769943,-0.5092252179873332,0.12580968009238108,0.9575234066599015,2.5672903217950718,2.2900460179099036,1.1925614229636166,1.5630573692038123,1.9329933181047383,-0.26419124276665046,3.226034750624375,-0.3436274762646461,0.03326476765043723,1.4595591237186676,0.42694183408394704,1.162548846164761,1.1321439407679112,-0.6545664545020534,-0.2904304927178063,2.263445511133267,1.6497305064842487,-0.4529950413267082 3193 Mitochondrial transport 35 86 3.5863126506661187 0.0003353868203472 O60830,Q99595,P23786,P51572,P45880,Q9NS69,Q15388,Q99797,O14737,Q9UJS0,O75964,O43772,P56385,Q8N4H5,O43615,O00165,Q15070,P24539,Q9UBX3,Q9GZY8,Q96EK5,P30536,O95831,Q9P0J0,Q14849,Q9Y512,P12235,O14925,P55786,Q16611,P05141,Q8WWC4,O95429,Q10713,Q9Y371 Processes and pathways GO Biological process msigdb_gobp 0,3,4,141,15,16,280,411,408,428,31,162,418,41,414,45,48,181,54,312,187,58,194,201,74,332,338,211,218,355,361,502,373,497,512 45,2085,408,211,800,414,162,0,1610,2788,2671,31,1316,2735,2889,373,2907,194,651,2140,361,1134,1063,1841,3129,338,1399,4,181,1997,2894,1657,58,2543,1797,3000,15,3131,2685,867,2867,1853,141,516,218,1199,418,2849,497,74,48,280,1917,355,557,1295,625,1112,1962,1375,2160,41,2832,502,2163,187,977,2779,3,411,312,2253,2808,16,201,1781,2921,54,1310,428,824,1230,512,332,1703,1272 2.832792341598909,-0.37059222129993374,0.9409967716069575,1.5376396248754793,0.40652433044515934,0.9243562959106226,1.7905380137060627,4.042548479567164,-0.11157482962869282,-0.902417991440706,-0.7760255732552376,3.0502155042807657,0.0566926794738131,-0.8385853324054076,-1.034071137875609,1.006432544850282,-1.0678476456651755,1.6375613175769943,0.5655565678430635,-0.39780592754705757,1.0384916258428032,0.17094088359372295,0.21533758545793177,-0.23818692761586824,-1.7850748625508288,1.1013384647454063,0.009638014956759703,3.6003046943759847,1.6858254775131012,-0.31690808027229783,-1.034071137875609,-0.13645324700708894,2.6556741514333573,-0.6545664545020534,-0.21241421080737602,-1.2422071670625843,3.285196134499565,-1.7850748625508288,-0.7760255732552376,0.36520852896444506,-1.00064563472387,-0.23818692761586824,1.9223825076951602,0.7514043268649677,1.5248183397306079,0.12580968009238108,0.9243562959106226,-0.9675653554604676,0.7869794546562088,2.536807538431712,2.800152733484291,1.3088453672804772,-0.26419124276665046,1.0543605595517835,0.6970721128067479,0.07992440556882748,0.6038310370230041,0.19322985148629535,-0.2904304927178063,0.03326476765043723,-0.39780592754705757,2.8899600348937455,-0.934824649241834,0.7869794546562088,-0.39780592754705757,1.6738619652882785,0.28059656391052684,-0.8703399800828923,3.6753208773984025,0.9409967716069575,1.1925614229636166,-0.4529950413267082,-0.902417991440706,3.2657379732892013,1.6006322940022837,-0.18686982059176915,-1.0678476456651755,2.732890881137026,0.07992440556882748,0.9243562959106226,0.40652433044515934,0.12580968009238108,0.7692555416447295,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Organophosphate ester transport 14 25 3.555526046421912 0.0003772235696815 P08183,Q99808,Q8TB61,P05141,P61916,Q8WTV0,Q14108,Q9H2D1,P12235,Q7Z3C6,Q9HC21,Q9BSK2,P12236,Q96GC9 Processes and pathways GO Biological process msigdb_gobp 129,321,101,361,457,43,14,47,338,471,405,212,217,220 505,361,129,338,217,1847,2640,888,654,1241,457,835,14,1112,471,101,929,43,220,321,212,1429,47,405,2256 0.7692555416447295,1.0384916258428032,2.0361169935164405,1.1013384647454063,1.5248183397306079,-0.23818692761586824,-0.7452104629394918,0.3443061993948582,0.5655565678430635,0.10296255264400622,0.8566305867164241,0.38594722827302785,3.309160878702859,0.19322985148629535,0.8394016868466264,2.2988294808347165,0.32323817115644027,2.871125247428219,1.5248183397306079,1.1473959441543768,1.5376396248754793,0.009638014956759703,2.813285883739657,0.9575234066599015,-0.4529950413267082 3193 SLC25 family of mitochondrial transporters 15 21 3.550993145901949 0.0003837804113007 O43772,O43808,P05141,Q9Y619,Q9BQT8,Q9H2D1,Q9Y6C9,Q70HW3,P12235,Q9HC21,Q9UBX3,Q9BSK2,P12236,Q9UJS0,Q9NZJ7 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 162,505,361,239,238,47,144,50,338,405,54,212,217,428,191 162,505,527,361,338,217,730,1111,870,1112,50,238,212,47,1599,405,191,54,428,239,144 1.7905380137060627,0.7692555416447295,0.7334243460639536,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.46730587199900714,0.19322985148629535,0.36520852896444506,0.19322985148629535,2.760120300435202,1.446271558144171,1.5376396248754793,2.813285883739657,-0.08691226787820137,0.9575234066599015,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171,1.9117156067218775 3193 Mitochondrial carrier domain superfamily [IPR023395] 15 21 3.550993145901949 0.0003837804113007 O43772,O43808,P05141,Q9Y619,Q9BQT8,Q9H2D1,Q9Y6C9,Q70HW3,P12235,Q9HC21,Q9UBX3,Q9BSK2,P12236,Q9UJS0,Q9NZJ7 Sequence InterPro Superfamily interpro_homologous_superfamily 162,505,361,239,238,47,144,50,338,405,54,212,217,428,191 162,505,527,361,338,217,730,1111,870,1112,50,238,212,47,1599,405,191,54,428,239,144 1.7905380137060627,0.7692555416447295,0.7334243460639536,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.46730587199900714,0.19322985148629535,0.36520852896444506,0.19322985148629535,2.760120300435202,1.446271558144171,1.5376396248754793,2.813285883739657,-0.08691226787820137,0.9575234066599015,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171,1.9117156067218775 3193 Mitochondrial substrate/solute carrier [IPR018108] 15 21 3.550993145901949 0.0003837804113007 O43772,O43808,P05141,Q9Y619,Q9BQT8,Q9H2D1,Q9Y6C9,Q70HW3,P12235,Q9HC21,Q9UBX3,Q9BSK2,P12236,Q9UJS0,Q9NZJ7 Sequence InterPro Repeat interpro_repeat 162,505,361,239,238,47,144,50,338,405,54,212,217,428,191 162,505,527,361,338,217,730,1111,870,1112,50,238,212,47,1599,405,191,54,428,239,144 1.7905380137060627,0.7692555416447295,0.7334243460639536,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.46730587199900714,0.19322985148629535,0.36520852896444506,0.19322985148629535,2.760120300435202,1.446271558144171,1.5376396248754793,2.813285883739657,-0.08691226787820137,0.9575234066599015,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171,1.9117156067218775 3193 Endoplasmic reticulum golgi intermediate compartment membrane 16 25 3.5350001338515216 0.0004077749518913 P24390,Q13190,P49755,Q12907,O15260,Q15904,P53634,P51572,Q03518,Q8N511,Q9UBR2,Q9Y282,Q9BVK6,Q96GC9,Q15363,Q9Y3B3 Localization GO Cellular component msigdb_gocc 2,354,417,490,259,230,487,141,111,49,244,85,444,220,29,30 798,259,604,1574,2,3087,867,417,141,487,656,111,490,354,29,230,49,220,444,2289,961,244,85,513,30 0.40652433044515934,1.3786129091151909,0.6227553904440447,-0.08691226787820137,3.7462657069794476,-1.5028434769808663,0.36520852896444506,0.9243562959106226,1.9223825076951602,0.8045775073895869,0.5655565678430635,2.2364631467360248,0.8045775073895869,1.0543605595517835,3.078186020550252,1.4595591237186676,2.7869149799952893,1.5248183397306079,0.8907287812193003,-0.4809780479553145,0.30200233977580343,1.4329036514563958,2.4339675988258307,0.7692555416447295,3.067058131253242 3193 Anion transmembrane transport 29 41 3.5323556870987 0.0004118749616839 P08183,P55011,P21796,P45880,Q9HC21,Q9Y6M7,P41440,O75915,O75746,Q9UJS0,Q96NB2,P53985,Q9H2D1,Q14728,Q9UBX3,Q9UHG3,P51798,Q13546,Q9BXP2,P12235,P12236,P53007,O60831,Q8TB61,P05141,Q9Y619,Q9BQT8,Q9Y277,O43808 Processes and pathways GO Biological process msigdb_gobp 129,636,7,15,405,151,654,528,527,428,677,169,47,305,54,59,184,714,475,338,217,730,478,101,361,239,238,247,505 505,478,527,528,361,2351,129,727,338,217,7,888,654,15,3156,184,730,169,636,1111,870,714,305,899,101,929,677,238,475,47,1599,879,405,1057,54,59,428,247,2083,239,151 0.7692555416447295,0.8220511190203319,0.7334243460639536,0.7334243460639536,1.0384916258428032,-0.5377405503528547,2.0361169935164405,0.46730587199900714,1.1013384647454063,1.5248183397306079,3.5491802513502524,0.3443061993948582,0.5655565678430635,3.285196134499565,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.19322985148629535,0.36520852896444506,0.48725623745593405,1.207423100369303,0.3443061993948582,2.2988294808347165,0.32323817115644027,0.5462030417796385,1.446271558144171,0.8394016868466264,2.813285883739657,-0.08691226787820137,0.36520852896444506,0.9575234066599015,0.23726642403703146,2.732890881137026,2.6556741514333573,0.9243562959106226,1.419454626258951,-0.3436274762646461,1.446271558144171,1.8465093473865353 3193 Receptor 10 28 3.5088179623706552 0.0004501028605801 O75381,Q9BUN8,Q567V2,A6NIH7,Q8WTV0,Q14108,P57105,Q9UQB8,Q13432,Q9NR77 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 193,165,5,9,43,14,276,84,25,61 9,2261,1705,193,2764,485,2351,568,633,1068,276,690,279,25,468,14,5,1763,43,1735,165,1386,61,1976,1391,2296,1876,84 3.4750650461264545,-0.4809780479553145,-0.16155054834083413,1.6375613175769943,-0.8703399800828923,0.8045775073895869,-0.5377405503528547,0.6786968138424812,0.5847653265563068,0.21533758545793177,1.3229726085415559,0.5267030007716262,1.3088453672804772,3.105660523374089,0.8394016868466264,3.309160878702859,3.5925647235517952,-0.18686982059176915,2.871125247428219,-0.16155054834083413,1.7905380137060627,0.03326476765043723,2.6412527563805264,-0.2904304927178063,0.03326476765043723,-0.4809780479553145,-0.23818692761586824,2.4420909128633217 3193 Transport vesicle 46 96 3.437477698507068 0.0005871590688528 P24390,Q9UI14,P20645,Q9NR31,Q7Z6M1,P61026,O15260,Q96A57,P50897,P61923,P62820,O00461,Q15363,Q9Y3B3,O43731,P49755,O15400,Q15019,Q15907,Q15437,Q9BVK6,Q9GZY8,P11279,O95295,Q9BT78,P55735,P05067,O15126,P11717,Q92542,P10321,O76024,P20020,Q9Y6Y8,P61421,O95249,O15498,Q13190,O60499,Q7L0J3,Q86Y82,P04439,O95782,Q9UKR5,O75592,O43760 Localization GO Cellular component msigdb_gocc 2,525,633,523,394,637,259,143,19,657,531,28,29,30,36,417,413,692,306,693,444,312,309,686,443,440,438,436,568,329,455,454,580,476,466,348,604,354,103,108,627,233,485,115,620,125 1098,28,2635,798,1571,1394,436,259,413,604,36,1705,125,103,1131,2137,1355,1574,620,454,2447,348,686,1194,942,485,1497,233,438,1990,455,309,568,580,1945,633,2,3119,1893,990,2864,1069,867,417,19,1287,1454,3156,1360,2504,2267,2321,440,1901,1666,637,1247,466,657,531,1625,1407,354,2689,3077,692,783,2157,29,998,693,306,1143,108,394,627,1048,329,1378,1767,143,443,444,312,961,1057,523,1933,2978,1696,525,115,986,30,710,476 0.19322985148629535,3.078186020550252,-0.7452104629394918,0.40652433044515934,-0.08691226787820137,0.009638014956759703,0.8907287812193003,1.3786129091151909,0.9243562959106226,0.6227553904440447,2.96913415144942,-0.16155054834083413,2.09550477869399,2.2812210779922095,0.17094088359372295,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,0.6038310370230041,0.8566305867164241,-0.5955921179420027,1.070123936480939,0.5267030007716262,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.446271558144171,0.8907287812193003,-0.31690808027229783,0.8566305867164241,1.1925614229636166,0.6786968138424812,0.6601866548649779,-0.2904304927178063,0.5847653265563068,3.7462657069794476,-1.7020688805675812,-0.26419124276665046,0.259018664523886,-1.00064563472387,0.21533758545793177,0.36520852896444506,0.9243562959106226,3.2108682288698214,0.07992440556882748,-0.014190283332690111,-2.0464349065431278,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,0.8907287812193003,-0.26419124276665046,-0.13645324700708894,0.5847653265563068,0.10296255264400622,0.8394016868466264,0.5655565678430635,0.7334243460639536,-0.11157482962869282,0.009638014956759703,1.0543605595517835,-0.7760255732552376,-1.4643510697454634,0.5267030007716262,0.42694183408394704,-0.39780592754705757,3.078186020550252,0.259018664523886,0.5267030007716262,1.207423100369303,0.17094088359372295,2.245500235348313,0.9739374379111466,0.6038310370230041,0.23726642403703146,1.1321439407679112,0.03326476765043723,-0.18686982059176915,1.9117156067218775,0.8907287812193003,0.8907287812193003,1.1925614229636166,0.30200233977580343,0.23726642403703146,0.7514043268649677,-0.26419124276665046,-1.1713430341599453,-0.13645324700708894,0.7514043268649677,2.2182584184461103,0.28059656391052684,3.067058131253242,0.5070546681307051,0.8394016868466264 3193 Organic anion transport 35 45 3.4374433673747333 0.0005872335055499 Q15758,P55011,P33527,P28288,Q9HC21,Q9Y6M7,P41440,O75915,O75746,Q9UJS0,Q9H2J7,Q96NB2,P53985,Q15042,Q9H2D1,Q14728,Q9UBX3,Q9NZJ7,Q99808,P07602,P12235,P12236,Q08722,P53007,Q9H9B4,O60831,Q8TB61,P08195,Q02978,P05141,P11166,Q9Y619,Q7L0J3,Q9BQT8,O43808 Processes and pathways GO Biological process msigdb_gobp 899,636,888,515,405,151,654,528,527,428,289,677,169,814,47,305,54,191,321,72,338,217,835,730,879,478,101,727,870,361,863,239,108,238,505 2181,1571,505,478,527,528,1889,361,2351,72,727,863,338,217,1710,515,888,654,730,169,636,3114,870,835,305,814,899,1112,954,108,101,929,677,321,238,47,289,1599,879,405,191,54,428,239,151 -0.4252722805882104,-0.08691226787820137,0.7692555416447295,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.26419124276665046,1.0384916258428032,-0.5377405503528547,2.5672903217950718,0.46730587199900714,0.36520852896444506,1.1013384647454063,1.5248183397306079,-0.16155054834083413,0.7514043268649677,0.3443061993948582,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.5847653265563068,-1.661294066844009,0.36520852896444506,0.38594722827302785,1.207423100369303,0.40652433044515934,0.3443061993948582,0.19322985148629535,0.30200233977580343,2.245500235348313,2.2988294808347165,0.32323817115644027,0.5462030417796385,1.1473959441543768,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,0.9575234066599015,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171,1.8465093473865353 3193 Inner mitochondrial membrane protein complex 25 70 3.433800255020415 0.0005951826129424 O60830,Q99595,P13073,P14406,Q9NVH1,Q9UDW1,Q8IYU8,O75964,O43676,Q9BPX6,P56385,Q13505,P24539,P47985,Q9P0J0,Q9Y512,Q9BUR5,O75306,O14925,P00403,P12236,Q96IX5,P21912,O14949,Q96CU9 Localization GO Cellular component msigdb_gocc 0,3,136,12,270,22,410,31,34,297,418,51,181,448,201,332,335,205,211,216,217,358,353,110,126 2134,1234,211,110,34,0,1443,205,2265,1610,1942,2671,31,593,3053,2350,216,1134,752,1196,1790,217,136,12,2766,1103,3149,2092,353,775,181,1997,3070,2610,1795,1796,1797,3155,448,3131,3152,1583,1199,418,51,2416,1209,660,557,1295,549,449,410,876,126,358,3,678,297,335,2253,270,719,698,201,22,1230,1019,332,649 -0.39780592754705757,0.10296255264400622,1.5376396248754793,2.2364631467360248,2.9927281115085713,4.042548479567164,-0.014190283332690111,1.5503857345605445,-0.4809780479553145,-0.11157482962869282,-0.2904304927178063,-0.7760255732552376,3.0502155042807657,0.6415400506909451,-1.3886547156284181,-0.5377405503528547,1.5248183397306079,0.17094088359372295,0.44720170401297976,0.12580968009238108,-0.21241421080737602,1.5248183397306079,1.9329933181047383,3.4056877380284694,-0.8703399800828923,0.19322985148629535,-2.0015302332107483,-0.37059222129993374,1.0543605595517835,0.42694183408394704,1.6858254775131012,-0.31690808027229783,-1.426290709801661,-0.7146987125093559,-0.21241421080737602,-0.21241421080737602,-0.21241421080737602,-2.0464349065431278,0.8737391734444331,-1.7850748625508288,-2.0015302332107483,-0.08691226787820137,0.12580968009238108,0.9243562959106226,2.746560633651398,-0.5665281275626076,0.12580968009238108,0.5655565678430635,0.6970721128067479,0.07992440556882748,0.7153141117668748,0.8737391734444331,0.9409967716069575,0.36520852896444506,2.09550477869399,1.0543605595517835,3.6753208773984025,0.5462030417796385,1.2514414118114898,1.1167917984678513,-0.4529950413267082,1.3509647782580774,0.48725623745593405,0.5267030007716262,1.6006322940022837,3.143317850644801,0.12580968009238108,0.259018664523886,1.1321439407679112,0.5847653265563068 3193 Organic acid transmembrane transport 24 29 3.37006746895223 0.0007514978125087 Q15758,P08183,P23786,P33527,P28288,P41440,O75915,O75746,Q9UJS0,Q9H2J7,Q96NB2,O43772,P53985,Q9H2D1,Q9UBX3,P31751,P53007,Q9H9B4,O60831,P08195,Q02978,P11166,Q9Y619,Q9BQT8 Processes and pathways GO Biological process msigdb_gobp 899,129,4,888,515,654,528,527,428,289,677,162,169,47,54,313,730,879,478,727,870,863,239,238 162,478,527,528,2351,129,727,863,4,515,313,1579,888,654,1853,730,169,870,899,929,677,238,47,289,1599,879,54,428,239 1.7905380137060627,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.5377405503528547,2.0361169935164405,0.46730587199900714,0.36520852896444506,3.6003046943759847,0.7514043268649677,1.1776036696350574,-0.08691226787820137,0.3443061993948582,0.5655565678430635,-0.23818692761586824,0.46730587199900714,1.7677180561785404,0.36520852896444506,0.3443061993948582,0.32323817115644027,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,2.732890881137026,0.9243562959106226,1.446271558144171 3193 Organic anion transmembrane transporter activity 25 29 3.3655890017631376 0.0007638042180242 Q15758,P33527,Q9HC21,Q9Y6M7,P41440,O75746,Q9UJS0,Q96NB2,P53985,Q9H2D1,Q14728,Q9UBX3,Q99808,P12235,P12236,P53007,Q9H9B4,Q8TB61,P08195,Q02978,P05141,P11166,Q9Y619,Q9BQT8,O43808 Functions GO Molecular function msigdb_gomf 899,888,405,151,654,527,428,677,169,47,305,54,321,338,217,730,879,101,727,870,361,863,239,238,505 2181,505,527,361,727,863,338,217,888,654,730,169,870,305,899,1112,954,101,677,321,238,47,1599,879,405,54,428,239,151 -0.4252722805882104,0.7692555416447295,0.7334243460639536,1.0384916258428032,0.46730587199900714,0.36520852896444506,1.1013384647454063,1.5248183397306079,0.3443061993948582,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.36520852896444506,1.207423100369303,0.3443061993948582,0.19322985148629535,0.30200233977580343,2.2988294808347165,0.5462030417796385,1.1473959441543768,1.446271558144171,2.813285883739657,-0.08691226787820137,0.36520852896444506,0.9575234066599015,2.732890881137026,0.9243562959106226,1.446271558144171,1.8465093473865353 3193 Protein localization to mitochondrion 23 59 3.3486898690315448 0.0008119462595448 O60830,Q99595,P51572,Q9NS69,Q9Y6C9,Q15388,Q99797,O14737,Q8N4H5,O43615,O00165,Q15070,Q9GZY8,P30536,O95831,Q9P0J0,Q9Y512,O14925,P55786,Q8WWC4,O95429,Q10713,Q9Y371 Processes and pathways GO Biological process msigdb_gobp 0,3,141,16,144,280,411,408,41,414,45,48,312,58,194,201,332,211,218,502,373,497,512 45,2085,1313,1098,408,211,800,414,0,2788,1316,2735,2889,373,2907,194,651,1063,3129,1991,2794,1399,1657,58,2144,2543,867,2867,141,516,218,2849,497,48,280,1917,557,1295,625,1962,41,2832,502,2779,3,411,312,2253,16,201,1781,2921,1310,1230,512,332,1703,1272,144 2.832792341598909,-0.37059222129993374,0.0566926794738131,0.19322985148629535,0.9409967716069575,1.5376396248754793,0.40652433044515934,0.9243562959106226,4.042548479567164,-0.902417991440706,0.0566926794738131,-0.8385853324054076,-1.034071137875609,1.006432544850282,-1.0678476456651755,1.6375613175769943,0.5655565678430635,0.21533758545793177,-1.7850748625508288,-0.31690808027229783,-0.902417991440706,0.009638014956759703,-0.13645324700708894,2.6556741514333573,-0.39780592754705757,-0.6545664545020534,0.36520852896444506,-1.00064563472387,1.9223825076951602,0.7514043268649677,1.5248183397306079,-0.9675653554604676,0.7869794546562088,2.800152733484291,1.3088453672804772,-0.26419124276665046,0.6970721128067479,0.07992440556882748,0.6038310370230041,-0.2904304927178063,2.8899600348937455,-0.934824649241834,0.7869794546562088,-0.8703399800828923,3.6753208773984025,0.9409967716069575,1.1925614229636166,-0.4529950413267082,3.2657379732892013,1.6006322940022837,-0.18686982059176915,-1.0678476456651755,0.07992440556882748,0.12580968009238108,0.7692555416447295,1.1321439407679112,-0.13645324700708894,0.10296255264400622,1.9117156067218775 3193 Active transmembrane transporter activity 26 69 3.3335756200012647 0.0008573736208288 Q15043,P08183,P13073,Q7KZN9,Q9UDW1,Q15388,Q9Y6M7,O95202,Q9H2J7,O43676,P53985,O75027,P16615,Q9UBX3,P51798,P47985,Q9P0J0,Q96ES6,Q9BXP2,P12235,O75306,Q9HD20,P00403,P12236,P05141,Q03518 Functions GO Molecular function msigdb_gomf 256,129,136,150,22,280,151,155,289,34,169,170,300,54,184,448,201,75,475,338,205,87,216,217,361,111 2134,1234,34,170,1443,205,2265,1942,593,3053,155,2350,216,712,2449,361,1134,129,727,752,1790,338,217,136,300,3149,580,2092,1846,2639,515,3070,1795,888,1617,2864,654,448,3152,3156,184,1583,730,169,636,466,994,1111,870,111,256,280,899,2416,1209,150,876,75,475,289,1599,87,2808,201,54,22,1980,151,649 -0.39780592754705757,0.10296255264400622,2.9927281115085713,1.744645033106282,-0.014190283332690111,1.5503857345605445,-0.4809780479553145,-0.2904304927178063,0.6415400506909451,-1.3886547156284181,1.8243030426289284,-0.5377405503528547,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,2.0361169935164405,0.46730587199900714,0.44720170401297976,-0.21241421080737602,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,-2.0015302332107483,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,0.7514043268649677,-1.426290709801661,-0.21241421080737602,0.3443061993948582,-0.11157482962869282,-1.00064563472387,0.5655565678430635,0.8737391734444331,-2.0015302332107483,-2.0464349065431278,1.6738619652882785,-0.08691226787820137,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.8394016868466264,0.259018664523886,0.19322985148629535,0.36520852896444506,2.2364631467360248,1.392310058750564,1.3088453672804772,0.3443061993948582,-0.5665281275626076,0.12580968009238108,1.8465093473865353,0.36520852896444506,2.5291039002629425,0.8394016868466264,1.280324185022697,-0.08691226787820137,2.4176108705977826,-0.902417991440706,1.6006322940022837,2.732890881137026,3.143317850644801,-0.2904304927178063,1.8465093473865353,0.5847653265563068 3193 Slc mediated transmembrane transport 12 21 3.333161108373445 0.0008586520567841 Q15043,Q9H2J7,Q99808,Q8TB61,P53985,Q8TAD4,Q70HW3,P12235,Q9UBX3,Q9Y6M7,P12236,P35613 Processes and pathways Reactome Pathways msigdb_reactome 256,289,321,101,169,105,50,338,54,151,217,317 361,727,863,338,217,3043,317,1659,169,636,256,899,954,50,105,101,321,289,1599,54,151 1.0384916258428032,0.46730587199900714,0.36520852896444506,1.1013384647454063,1.5248183397306079,-1.3514355919674153,1.162548846164761,-0.13645324700708894,1.7677180561785404,0.5847653265563068,1.392310058750564,0.3443061993948582,0.30200233977580343,2.760120300435202,2.2812210779922095,2.2988294808347165,1.1473959441543768,1.280324185022697,-0.08691226787820137,2.732890881137026,1.8465093473865353 3193 Intrinsic component of mitochondrial membrane 27 47 3.3267246822157865 0.0008787314673315 O60830,Q99595,O43819,Q6P4A7,Q9NVH1,Q16891,P57105,Q9HC21,P17152,Q15388,O96008,Q5XKP0,Q96NB2,Q9BPX6,Q9Y2R0,Q9H3K2,Q15070,Q13505,Q9GZY8,Q6UXV4,Q8IWA4,Q9Y512,Q9BUR5,P12235,O14925,Q16611,Q16134 Localization GO Cellular component msigdb_gocc 0,3,514,142,270,660,276,405,529,280,651,549,677,297,44,302,48,51,312,449,328,332,335,338,211,355,613 211,514,0,1610,1026,1316,2735,651,338,529,3155,2614,1853,276,1111,51,48,280,613,355,660,1295,549,142,449,328,1375,2160,876,2163,677,3,297,335,764,312,302,879,2387,405,2808,270,698,2179,44,1019,332 1.5376396248754793,0.7514043268649677,4.042548479567164,-0.11157482962869282,0.23726642403703146,0.0566926794738131,-0.8385853324054076,0.5655565678430635,1.1013384647454063,0.7334243460639536,-2.0464349065431278,-0.7146987125093559,-0.23818692761586824,1.3229726085415559,0.19322985148629535,2.746560633651398,2.800152733484291,1.3088453672804772,0.6227553904440447,1.0543605595517835,0.5655565678430635,0.07992440556882748,0.7153141117668748,1.9117156067218775,0.8737391734444331,1.1321439407679112,0.03326476765043723,-0.39780592754705757,0.36520852896444506,-0.39780592754705757,0.5462030417796385,3.6753208773984025,1.2514414118114898,1.1167917984678513,0.44720170401297976,1.1925614229636166,1.2221896821440608,0.36520852896444506,-0.5377405503528547,0.9575234066599015,-0.902417991440706,1.3509647782580774,0.5267030007716262,-0.39780592754705757,2.8520707218101506,0.259018664523886,1.1321439407679112 3193 Predicted secreted proteins 20 48 3.3218760888595704 0.0008941439212435 P26583,P02786,P80303,Q9NZ08,P43490,O94919,Q9HB40,Q15165,Q8WUJ1,P84157,Q02818,P05067,Q8N128,Q9UMX5,P61916,Q08380,Q9BUR5,O00584,Q9Y4P3,Q9BTY2 Functions Protein Atlas Protein class protein_atlas_protein_class 380,265,24,287,33,163,42,176,179,304,55,438,196,453,457,202,335,337,253,250 337,1236,1396,1167,1102,967,163,265,1889,438,1613,1988,802,2930,1710,1654,2932,380,33,2193,2267,457,731,24,1760,304,55,1363,202,2550,950,498,176,1861,196,3136,179,1682,562,1053,250,335,1929,935,42,287,453,253 1.1013384647454063,0.10296255264400622,0.009638014956759703,0.1484683010782358,0.19322985148629535,0.28059656391052684,1.7905380137060627,1.3648314259575298,-0.26419124276665046,0.8907287812193003,-0.11157482962869282,-0.31690808027229783,0.40652433044515934,-1.101981072569348,-0.16155054834083413,-0.13645324700708894,-1.101981072569348,0.9902400838282385,3.01019588582792,-0.4252722805882104,-0.4809780479553145,0.8566305867164241,0.46730587199900714,3.1219129348274657,-0.18686982059176915,1.207423100369303,2.69120665946763,0.03326476765043723,1.575655220295083,-0.6545664545020534,0.30200233977580343,0.7869794546562088,1.7213144397174807,-0.23818692761586824,1.6253223144467295,-1.8273246014917721,1.6977216604154457,-0.13645324700708894,0.6970721128067479,0.23726642403703146,1.4059236947909328,1.1167917984678513,-0.26419124276665046,0.32323817115644027,2.8899600348937455,1.2946295225860096,0.8737391734444331,1.4059236947909328 3193 Anion transmembrane transporter activity 28 46 3.313972769859692 0.0009198046436784 Q15043,P55011,P21796,Q9C0H2,P45880,Q9HC21,Q9Y6M7,P41440,O75746,Q9UJS0,Q9NW15,P53985,Q9H2D1,Q14728,Q9UBX3,P51798,Q99808,Q9BXP2,Q96S66,P12235,P12236,Q8TB61,P05141,Q9Y619,Q9BQT8,O43681,Q9Y277,O43808 Functions GO Molecular function msigdb_gomf 256,636,7,13,15,405,151,654,527,428,168,169,47,305,54,184,321,475,474,338,217,101,361,239,238,619,247,505 2964,2181,619,505,527,361,727,3092,863,338,217,7,888,654,15,3156,184,730,169,636,870,305,256,899,1921,1112,954,101,929,677,474,321,238,475,13,47,1599,879,405,168,54,428,247,239,2443,151 -1.1713430341599453,-0.4252722805882104,0.6038310370230041,0.7692555416447295,0.7334243460639536,1.0384916258428032,0.46730587199900714,-1.5417758052175927,0.36520852896444506,1.1013384647454063,1.5248183397306079,3.5491802513502524,0.3443061993948582,0.5655565678430635,3.285196134499565,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.36520852896444506,1.207423100369303,1.392310058750564,0.3443061993948582,-0.26419124276665046,0.19322985148629535,0.30200233977580343,2.2988294808347165,0.32323817115644027,0.5462030417796385,0.8394016868466264,1.1473959441543768,1.446271558144171,0.8394016868466264,3.351325980333631,2.813285883739657,-0.08691226787820137,0.36520852896444506,0.9575234066599015,1.7791593908234755,2.732890881137026,0.9243562959106226,1.419454626258951,1.446271558144171,-0.5665281275626076,1.8465093473865353 3193 Glycoprotein biosynthetic process 23 49 3.289996702754302 0.0010018855676303 Q7LGA3,Q13724,O60476,O43505,Q9HC07,P35610,Q9H4A6,Q96L58,Q6ZXV5,Q86YN1,O60502,Q9Y5P6,Q8WVQ1,Q9BT22,Q2TAA5,Q92542,Q9BV10,P46977,Q8NCH0,Q9NQX7,Q10471,Q16706,Q99805 Processes and pathways GO Biological process msigdb_gobp 131,517,398,275,146,288,426,291,559,177,52,445,311,316,326,329,199,206,82,106,489,362,367 2605,966,858,2394,3012,275,398,52,1396,1166,1355,2089,687,1030,1502,288,1896,206,713,833,1667,1909,489,517,872,362,326,559,131,1765,177,82,587,311,329,291,367,316,199,1973,1222,426,146,106,1643,1483,1696,445,3160 -0.7146987125093559,0.28059656391052684,0.36520852896444506,-0.5665281275626076,-1.2782188724392092,1.3229726085415559,0.9575234066599015,2.7397396070190534,0.009638014956759703,0.1484683010782358,0.03326476765043723,-0.37059222129993374,0.5267030007716262,0.23726642403703146,-0.03822288271037234,1.280324185022697,-0.26419124276665046,1.5503857345605445,0.48725623745593405,0.38594722827302785,-0.13645324700708894,-0.26419124276665046,0.8045775073895869,0.7514043268649677,0.36520852896444506,1.0384916258428032,1.1321439407679112,0.6970721128067479,1.985222235335816,-0.18686982059176915,1.7095511162040427,2.4420909128633217,0.6601866548649779,1.1925614229636166,1.1321439407679112,1.2659284528512882,1.0225160037257737,1.1776036696350574,1.6130128562407051,-0.2904304927178063,0.12580968009238108,0.9243562959106226,1.9009921408923331,2.263445511133267,-0.11157482962869282,-0.014190283332690111,-0.13645324700708894,0.8907287812193003,-2.1379443966160254 3193 Trans golgi network membrane 15 28 3.2799954763945576 0.0010380875109281 P56377,P53365,P20645,Q7Z6M1,Q9UID3,Q969E2,O60499,P53367,Q9HC07,O15127,Q8N2H4,O14828,P05067,O15126,P11717 Localization GO Cellular component msigdb_gocc 545,261,633,394,615,228,103,248,146,274,182,462,438,436,568 462,436,274,1705,1492,103,438,1990,568,633,1897,261,248,545,1901,833,1625,1910,2157,394,182,1214,228,1347,666,1183,146,615 0.8394016868466264,0.8907287812193003,1.3229726085415559,-0.16155054834083413,-0.03822288271037234,2.2812210779922095,0.8907287812193003,-0.31690808027229783,0.6786968138424812,0.5847653265563068,-0.26419124276665046,1.3786129091151909,1.4059236947909328,0.7153141117668748,-0.26419124276665046,0.38594722827302785,-0.11157482962869282,-0.26419124276665046,-0.39780592754705757,0.9739374379111466,1.6858254775131012,0.12580968009238108,1.472767115384539,0.0566926794738131,0.5655565678430635,0.1484683010782358,1.9009921408923331,0.6227553904440447 3193 Protein insertion into membrane 12 26 3.274020148568167 0.0010602905078371 Q15629,Q9P0J0,Q9Y512,Q9NPA0,Q9NS69,Q15070,Q8WWC4,O43681,P61619,O14737,Q96A33,P46379 Processes and pathways GO Biological process msigdb_gobp 64,201,332,336,16,48,502,619,530,408,284,62 408,619,1747,1316,1063,1657,2543,62,530,1549,48,64,1295,661,2280,1554,502,284,336,16,909,201,1230,332,1703,1272 0.9409967716069575,0.6038310370230041,-0.18686982059176915,0.0566926794738131,0.21533758545793177,-0.13645324700708894,-0.6545664545020534,2.6339966056994,0.7334243460639536,-0.062462590653624604,2.800152733484291,2.62670988147732,0.07992440556882748,0.5655565678430635,-0.4809780479553145,-0.062462590653624604,0.7869794546562088,1.2946295225860096,1.1167917984678513,3.2657379732892013,0.3443061993948582,1.6006322940022837,0.12580968009238108,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Glycosidase 12 18 3.270993192964745 0.0010717049001305 P10253,P54802,P06865,P06280,Q16706,P16278,O60476,P04066,O60502,P04062,Q9BTY2,O43598 Functions Protein Atlas Molecular function protein_atlas_molecular_function 102,166,293,298,362,11,398,400,52,122,250,446 2086,446,398,52,122,400,298,293,726,102,11,1358,166,2050,517,1726,362,250 -0.37059222129993374,0.8737391734444331,0.9575234066599015,2.7397396070190534,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,2.2900460179099036,3.418959561273887,0.03326476765043723,1.7791593908234755,-0.3436274762646461,0.7514043268649677,-0.16155054834083413,1.0384916258428032,1.4059236947909328 3193 Receptor 14 34 3.2619645978088534 0.0011064296040674 P24390,Q5KU26,O43731,P02786,Q8WTV0,Q14108,O15173,Q9NS69,Q14739,O00264,Q9Y5M8,P11279,Q99720,P35613 Functions Protein Atlas Molecular function protein_atlas_molecular_function 2,422,36,265,43,14,76,16,147,371,183,309,26,317 371,1236,858,76,36,265,2351,439,2314,2674,2226,1890,309,568,1654,633,2,317,731,950,14,147,839,899,422,43,930,1736,678,26,16,2082,183,2904 1.006432544850282,0.10296255264400622,0.36520852896444506,2.5057902110255577,2.96913415144942,1.3648314259575298,-0.5377405503528547,0.8907287812193003,-0.5092252179873332,-0.7760255732552376,-0.4529950413267082,-0.26419124276665046,1.1925614229636166,0.6786968138424812,-0.13645324700708894,0.5847653265563068,3.7462657069794476,1.162548846164761,0.46730587199900714,0.30200233977580343,3.309160878702859,1.8684775279957868,0.38594722827302785,0.3443061993948582,0.9243562959106226,2.871125247428219,0.32323817115644027,-0.16155054834083413,0.5462030417796385,3.0892345539041384,3.2657379732892013,-0.3436274762646461,1.6858254775131012,-1.034071137875609 3193 Ceramide metabolic process 10 17 3.257700118554931 0.0011231903197326 P06865,P06280,O95470,P17900,Q16880,Q8NCC3,Q13510,O15269,P04062,Q96G23 Processes and pathways GO Biological process msigdb_gobp 293,298,171,234,273,80,116,303,122,159 303,1060,800,171,122,298,293,726,234,917,116,273,1295,80,159,367,707 1.207423100369303,0.21533758545793177,0.40652433044515934,1.744645033106282,2.153135324237049,1.2368621349000533,1.2514414118114898,0.46730587199900714,1.446271558144171,0.32323817115644027,2.1998773817605315,1.3370121237135937,0.07992440556882748,2.474223234824225,1.8243030426289284,1.0225160037257737,0.5070546681307051 3193 Ion transport 22 51 3.2319052334367173 0.0012296782977219 Q15043,Q8NE01,P21796,Q93050,Q9C0H2,P45880,Q9Y6M7,O95202,O75964,Q9H2J7,Q9BPX6,P56385,P16615,P24539,P51798,Q9Y487,Q96S66,Q9UM00,Q15904,Q8TAD4,Q9Y277,Q6P4Q7 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 256,128,7,138,13,15,151,155,31,289,297,418,300,181,184,71,474,214,230,105,247,375 2964,2671,31,155,651,712,2449,1134,3092,300,580,1846,2639,7,181,1997,1797,1617,2864,15,3131,3156,184,2004,636,1199,418,466,994,1808,256,230,1921,375,128,876,105,929,138,474,297,1054,13,1928,289,1980,214,247,71,2443,151 -1.1713430341599453,-0.7760255732552376,3.0502155042807657,1.8243030426289284,0.5655565678430635,0.48725623745593405,-0.5955921179420027,0.17094088359372295,-1.5417758052175927,1.2368621349000533,0.6601866548649779,-0.23818692761586824,-0.7452104629394918,3.5491802513502524,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,3.285196134499565,-1.7850748625508288,-2.0464349065431278,1.6738619652882785,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.259018664523886,-0.21241421080737602,1.392310058750564,1.4595591237186676,-0.26419124276665046,1.006432544850282,2.075908277865556,0.36520852896444506,2.2812210779922095,0.32323817115644027,1.9329933181047383,0.8394016868466264,1.2514414118114898,0.23726642403703146,3.351325980333631,-0.26419124276665046,1.280324185022697,-0.2904304927178063,1.5376396248754793,1.419454626258951,2.582335824717171,-0.5665281275626076,1.8465093473865353 3193 Coated vesicle 28 89 3.216053166972292 0.0012996675161904 P24390,P02786,P51572,Q14108,Q15363,Q9Y3B3,O43731,P49755,O00165,Q8N511,Q9Y5X1,Q9BVK6,P55735,P05067,O15126,Q5VW38,P10321,Q9Y6Y8,Q9Y282,P42892,Q13190,Q12907,O00443,P53634,P04439,O95782,Q9UBR2,Q9Y3A6 Localization GO Cellular component msigdb_gocc 2,265,141,14,29,30,36,417,45,49,308,444,440,438,436,68,455,476,85,91,354,490,350,487,233,485,244,513 45,1313,1883,350,2635,798,1394,436,36,1705,2222,2137,1355,1574,2764,2447,1194,942,485,1497,265,233,438,1990,455,3129,2354,568,1945,633,2,990,91,1069,867,417,777,1454,141,1360,2504,2267,487,1584,2321,440,1901,1247,657,2747,1625,1906,490,354,2689,14,1512,783,29,998,693,1465,2328,68,1211,49,819,1344,444,666,1221,822,1057,523,1224,720,1565,1933,244,2978,2923,1603,2028,85,513,30,308,710,476 2.832792341598909,0.0566926794738131,-0.26419124276665046,1.0543605595517835,-0.7452104629394918,0.40652433044515934,0.009638014956759703,0.8907287812193003,2.96913415144942,-0.16155054834083413,-0.4529950413267082,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.8703399800828923,-0.5955921179420027,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.3648314259575298,1.446271558144171,0.8907287812193003,-0.31690808027229783,0.8566305867164241,-1.7850748625508288,-0.5377405503528547,0.6786968138424812,-0.2904304927178063,0.5847653265563068,3.7462657069794476,0.259018664523886,2.359178009634381,0.21533758545793177,0.36520852896444506,0.9243562959106226,0.42694183408394704,-0.014190283332690111,1.9223825076951602,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,0.8045775073895869,-0.08691226787820137,-0.5092252179873332,0.8907287812193003,-0.26419124276665046,0.10296255264400622,0.5655565678430635,-0.8385853324054076,-0.11157482962869282,-0.26419124276665046,0.8045775073895869,1.0543605595517835,-0.7760255732552376,3.309160878702859,-0.03822288271037234,0.42694183408394704,3.078186020550252,0.259018664523886,0.5267030007716262,-0.014190283332690111,-0.5092252179873332,2.5972531017791676,0.12580968009238108,2.7869149799952893,0.40652433044515934,0.0566926794738131,0.8907287812193003,0.5655565678430635,0.12580968009238108,0.40652433044515934,0.23726642403703146,0.7514043268649677,0.12580968009238108,0.48725623745593405,-0.062462590653624604,-0.26419124276665046,1.4329036514563958,-1.1713430341599453,-1.0678476456651755,-0.08691226787820137,-0.31690808027229783,2.4339675988258307,0.7692555416447295,3.067058131253242,1.207423100369303,0.5070546681307051,0.8394016868466264 3193 Membrane lipid biosynthetic process 11 20 3.2119610281521784 0.0013183225757014 Q06136,Q9P035,O95470,Q9H490,Q16880,Q99805,O15269,Q8NBX0,Q13510,P04062,Q96G23 Processes and pathways GO Biological process msigdb_gobp 99,524,171,368,273,367,303,21,116,122,159 303,1060,1166,171,122,1847,99,116,273,1295,21,519,1683,159,1971,367,368,707,524,2256 1.207423100369303,0.21533758545793177,0.1484683010782358,1.744645033106282,2.153135324237049,-0.23818692761586824,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.07992440556882748,3.148622465340775,0.7514043268649677,-0.13645324700708894,1.8243030426289284,-0.2904304927178063,1.0225160037257737,1.0225160037257737,0.5070546681307051,0.7514043268649677,-0.4529950413267082 3193 Retrograde vesicle mediated transport golgi to endoplasmic reticulum 11 28 3.206623864693494 0.0013430247257124 Q9H4A6,P24390,O43731,P49755,Q12981,Q12893,P84085,Q9P2W9,O15258,Q9Y282,P42858 Processes and pathways GO Biological process msigdb_gobp 426,2,36,417,420,325,458,100,351,85,341 1352,2635,351,36,1574,1169,2,990,341,1069,1241,417,2267,657,833,458,325,490,420,737,1118,1259,1215,426,1183,100,1933,85 0.03326476765043723,-0.7452104629394918,1.0543605595517835,2.96913415144942,-0.08691226787820137,0.1484683010782358,3.7462657069794476,0.259018664523886,1.1013384647454063,0.21533758545793177,0.10296255264400622,0.9243562959106226,-0.4809780479553145,0.5655565678430635,0.38594722827302785,0.8566305867164241,1.1321439407679112,0.8045775073895869,0.9243562959106226,0.46730587199900714,0.19322985148629535,0.10296255264400622,0.12580968009238108,0.9243562959106226,0.1484683010782358,2.3075717767503545,-0.26419124276665046,2.4339675988258307 3193 Glycoprotein metabolic process 24 56 3.205768507772298 0.0013470230716958 Q7LGA3,Q13724,O60476,O43505,Q9HC07,P62820,P35610,Q9H4A6,Q96L58,Q6ZXV5,Q86YN1,O60502,Q9Y5P6,Q8WVQ1,Q9BT22,Q2TAA5,Q92542,Q9BV10,P46977,Q8NCH0,Q9NQX7,Q10471,Q16706,Q99805 Processes and pathways GO Biological process msigdb_gobp 131,517,398,275,146,531,288,426,291,559,177,52,445,311,316,326,329,199,206,82,106,489,362,367 2605,2086,966,858,2394,3012,275,398,52,1396,1166,1355,2089,687,1030,2188,1502,288,1896,206,713,531,833,1667,1909,489,517,872,1726,362,326,559,131,1765,177,82,587,311,329,291,3098,367,2025,316,199,1973,961,1222,426,146,106,1643,1483,1696,445,3160 -0.7146987125093559,-0.37059222129993374,0.28059656391052684,0.36520852896444506,-0.5665281275626076,-1.2782188724392092,1.3229726085415559,0.9575234066599015,2.7397396070190534,0.009638014956759703,0.1484683010782358,0.03326476765043723,-0.37059222129993374,0.5267030007716262,0.23726642403703146,-0.4252722805882104,-0.03822288271037234,1.280324185022697,-0.26419124276665046,1.5503857345605445,0.48725623745593405,0.7334243460639536,0.38594722827302785,-0.13645324700708894,-0.26419124276665046,0.8045775073895869,0.7514043268649677,0.36520852896444506,-0.16155054834083413,1.0384916258428032,1.1321439407679112,0.6970721128067479,1.985222235335816,-0.18686982059176915,1.7095511162040427,2.4420909128633217,0.6601866548649779,1.1925614229636166,1.1321439407679112,1.2659284528512882,-1.5417758052175927,1.0225160037257737,-0.31690808027229783,1.1776036696350574,1.6130128562407051,-0.2904304927178063,0.30200233977580343,0.12580968009238108,0.9243562959106226,1.9009921408923331,2.263445511133267,-0.11157482962869282,-0.014190283332690111,-0.13645324700708894,0.8907287812193003,-2.1379443966160254 3193 Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 15 32 3.192338757094385 0.0014112571375868 O75845,Q9BU89,Q15800,P30519,O00767,Q9NWT6,P16435,Q8NB78,P13674,P09601,Q32P28,Q14534,O95864,Q6UW02,Q16850 Functions GO Molecular function msigdb_gomf 224,520,35,69,360,564,299,78,555,17,432,403,374,189,158 2605,360,1442,1940,1396,620,224,374,1652,17,555,299,69,1712,1902,1667,1365,403,35,158,432,1763,1515,189,2158,1963,78,520,2385,564,2491,2391 -0.7146987125093559,1.0384916258428032,-0.014190283332690111,-0.2904304927178063,0.009638014956759703,0.6038310370230041,1.4858962903240147,1.006432544850282,-0.13645324700708894,3.250973747172662,0.6970721128067479,1.2368621349000533,2.589810382359061,-0.16155054834083413,-0.26419124276665046,-0.13645324700708894,0.03326476765043723,0.9575234066599015,2.975065555239934,1.8243030426289284,0.9076007240012801,-0.18686982059176915,-0.03822288271037234,1.661830514045592,-0.39780592754705757,-0.2904304927178063,2.5057902110255577,0.7514043268649677,-0.5377405503528547,0.6970721128067479,-0.5955921179420027,-0.5377405503528547 3193 Glycosaminoglycan metabolism 8 12 3.186849391282702 0.0014383164982783 Q96L58,Q7LGA3,Q8TB61,P54802,P06865,P16278,Q8NCH0,O43505 Processes and pathways Reactome Pathways msigdb_reactome 291,131,101,166,293,11,82,275 2031,275,293,726,310,11,166,131,82,101,291,1696 -0.3436274762646461,1.3229726085415559,1.2514414118114898,0.46730587199900714,1.1925614229636166,3.418959561273887,1.7791593908234755,1.985222235335816,2.4420909128633217,2.2988294808347165,1.2659284528512882,-0.13645324700708894 3193 Hydrolase activity hydrolyzing o glycosyl compounds 11 19 3.1724859662513945 0.0015113986380697 P54802,P10253,P06865,P06280,P16278,Q16706,P17900,O60476,O60502,P04062,Q9BTY2 Functions GO Molecular function msigdb_gomf 166,102,293,298,11,362,234,398,52,122,250 2086,398,52,122,400,298,293,726,102,11,234,1358,166,517,1726,362,2756,250,793 -0.37059222129993374,0.9575234066599015,2.7397396070190534,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,2.2900460179099036,3.418959561273887,1.446271558144171,0.03326476765043723,1.7791593908234755,0.7514043268649677,-0.16155054834083413,1.0384916258428032,-0.8385853324054076,1.4059236947909328,0.42694183408394704 3193 Transporter 74 182 3.168699449949018 0.0015312264716915 Q15043,P08183,P24390,Q9UI14,Q9BQE5,Q9Y5L0,Q8TAG9,Q93050,Q8TEX9,P28288,P51572,O95721,Q9Y6C9,Q9HC07,Q9HC21,P61619,Q9Y6M7,Q15388,O75746,O95202,Q00765,Q15363,Q9Y3B3,Q9UJS0,Q9H2J7,O43731,O43772,P49755,P56385,O15400,P53985,O75027,P16615,Q9H2V7,Q9H2D1,Q15070,Q70HW3,P24539,Q9UBX3,Q8N2H4,P11279,Q9BVK6,P55735,Q92544,Q9NZJ7,Q99808,Q9Y487,Q96ES6,P13473,P52292,Q9BXP2,P12235,Q9BSK2,P61421,P12236,Q9HD45,O95249,Q13190,Q9P2W9,Q8TB61,Q12907,O60499,Q8TAD4,Q9Y619,Q9BQT8,Q7L0J3,P17900,P05141,Q03518,Q99805,Q8IXU6,Q9Y3A6,O43760,O43808 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 256,129,2,525,6,397,518,138,395,515,141,399,144,146,405,530,151,280,527,155,546,29,30,428,289,36,162,417,418,413,169,170,300,174,47,48,50,181,54,182,309,444,440,315,191,321,71,75,204,333,475,338,212,466,217,90,348,354,100,101,490,103,105,239,238,108,234,361,111,367,117,513,125,505 2345,2604,1313,1314,685,1745,2635,1274,798,413,36,125,162,505,103,1131,2637,1132,2137,170,1133,527,2671,2447,155,348,2496,1194,942,399,651,712,2449,361,1134,129,727,1990,863,309,338,217,204,300,234,580,1846,2639,2,181,1997,515,1893,888,990,1797,2544,2864,654,1069,1241,867,417,141,1360,333,2721,730,2504,2267,1584,169,2321,1854,2004,2547,636,440,1199,545,418,1800,466,530,657,2747,994,1111,1625,546,870,111,1910,1250,623,1407,490,354,2689,1548,2415,2693,256,48,2156,2157,29,280,899,1921,1112,954,50,108,1730,627,117,586,182,1002,105,518,101,1865,395,1966,1259,315,931,138,787,819,1924,75,588,677,977,1522,845,367,321,6,238,2522,212,2071,444,475,1973,1221,47,289,174,1599,879,146,405,90,2808,191,2632,2256,720,100,1933,2178,54,1980,525,1646,428,855,1700,986,513,30,71,397,239,710,144,151 -0.5377405503528547,-0.7146987125093559,0.0566926794738131,0.0566926794738131,0.5267030007716262,-0.18686982059176915,-0.7452104629394918,0.07992440556882748,0.40652433044515934,0.9243562959106226,2.96913415144942,2.09550477869399,1.7905380137060627,0.7692555416447295,2.2812210779922095,0.17094088359372295,-0.7452104629394918,0.17094088359372295,-0.39780592754705757,1.744645033106282,0.17094088359372295,0.7334243460639536,-0.7760255732552376,-0.5955921179420027,1.8243030426289284,1.070123936480939,-0.6249367779380635,0.12580968009238108,0.30200233977580343,0.9575234066599015,0.5655565678430635,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,2.0361169935164405,0.46730587199900714,-0.31690808027229783,0.36520852896444506,1.1925614229636166,1.1013384647454063,1.5248183397306079,1.5630573692038123,1.2368621349000533,1.446271558144171,0.6601866548649779,-0.23818692761586824,-0.7452104629394918,3.7462657069794476,1.6858254775131012,-0.31690808027229783,0.7514043268649677,-0.26419124276665046,0.3443061993948582,0.259018664523886,-0.21241421080737602,-0.6545664545020534,-1.00064563472387,0.5655565678430635,0.21533758545793177,0.10296255264400622,0.36520852896444506,0.9243562959106226,1.9223825076951602,0.03326476765043723,1.1167917984678513,-0.8071488815311059,0.46730587199900714,-0.6249367779380635,-0.4809780479553145,-0.08691226787820137,1.7677180561785404,-0.5092252179873332,-0.23818692761586824,-0.31690808027229783,-0.6545664545020534,0.5847653265563068,0.8907287812193003,0.12580968009238108,0.7153141117668748,0.9243562959106226,-0.21241421080737602,0.8394016868466264,0.7334243460639536,0.5655565678430635,-0.8385853324054076,0.259018664523886,0.19322985148629535,-0.11157482962869282,0.7153141117668748,0.36520852896444506,2.2364631467360248,-0.26419124276665046,0.10296255264400622,0.6038310370230041,0.009638014956759703,0.8045775073895869,1.0543605595517835,-0.7760255732552376,-0.062462590653624604,-0.5665281275626076,-0.7760255732552376,1.392310058750564,2.800152733484291,-0.39780592754705757,-0.39780592754705757,3.078186020550252,1.3088453672804772,0.3443061993948582,-0.26419124276665046,0.19322985148629535,0.30200233977580343,2.760120300435202,2.245500235348313,-0.16155054834083413,0.6038310370230041,2.1906198942531567,0.6601866548649779,1.6858254775131012,0.259018664523886,2.2812210779922095,0.7514043268649677,2.2988294808347165,-0.23818692761586824,0.9739374379111466,-0.2904304927178063,0.10296255264400622,1.1776036696350574,0.32323817115644027,1.9329933181047383,0.42694183408394704,0.40652433044515934,-0.26419124276665046,2.5291039002629425,0.6601866548649779,0.5462030417796385,0.28059656391052684,-0.03822288271037234,0.38594722827302785,1.0225160037257737,1.1473959441543768,3.5925647235517952,1.446271558144171,-0.6249367779380635,1.5376396248754793,-0.3436274762646461,0.8907287812193003,0.8394016868466264,-0.2904304927178063,0.12580968009238108,2.813285883739657,1.280324185022697,1.7330122185385242,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.376064301841973,-0.902417991440706,1.6497305064842487,-0.7146987125093559,-0.4529950413267082,0.48725623745593405,2.3075717767503545,-0.26419124276665046,-0.39780592754705757,2.732890881137026,-0.2904304927178063,0.7514043268649677,-0.11157482962869282,0.9243562959106226,0.38594722827302785,-0.13645324700708894,0.28059656391052684,0.7692555416447295,3.067058131253242,2.582335824717171,0.9739374379111466,1.446271558144171,0.5070546681307051,1.9117156067218775,1.8465093473865353 3193 Glycosphingolipid metabolism 10 17 3.160390156429067 0.0015755800124779 P07602,P06865,P16278,P17900,Q16880,Q13510,Q8NBJ7,P04062,P10619,Q9NZJ7 Processes and pathways Reactome Pathways msigdb_reactome 72,293,11,234,273,116,56,122,127,191 617,619,122,298,293,72,726,127,2891,11,234,116,273,56,2120,707,191 0.6038310370230041,0.6038310370230041,2.153135324237049,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-1.034071137875609,3.418959561273887,1.446271558144171,2.1998773817605315,1.3370121237135937,2.69120665946763,-0.37059222129993374,0.5070546681307051,1.6497305064842487 3193 Transport vesicle membrane 21 45 3.1526400267152725 0.0016180119863182 Q9NR31,P62820,Q15363,Q9Y3B3,P49755,Q15907,Q15437,P55735,O15126,P10321,O76024,P20020,Q9Y6Y8,Q13190,O60499,Q7L0J3,Q86Y82,O95782,P04439,O75592,O43760 Localization GO Cellular component msigdb_gocc 523,531,29,30,417,306,693,440,436,455,454,580,476,354,103,108,627,485,233,620,125 1098,798,1394,436,1705,125,103,2137,1355,1574,620,454,2447,686,1194,942,485,1497,233,1990,455,580,1945,867,417,1287,1360,2321,440,1666,531,1625,354,783,29,998,693,306,108,627,1378,523,2978,30,476 0.19322985148629535,0.40652433044515934,0.009638014956759703,0.8907287812193003,-0.16155054834083413,2.09550477869399,2.2812210779922095,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,0.6038310370230041,0.8566305867164241,-0.5955921179420027,0.5267030007716262,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.446271558144171,-0.31690808027229783,0.8566305867164241,0.6601866548649779,-0.2904304927178063,0.36520852896444506,0.9243562959106226,0.07992440556882748,0.03326476765043723,-0.5092252179873332,0.8907287812193003,-0.13645324700708894,0.7334243460639536,-0.11157482962869282,1.0543605595517835,0.42694183408394704,3.078186020550252,0.259018664523886,0.5267030007716262,1.207423100369303,2.245500235348313,0.6038310370230041,0.03326476765043723,0.7514043268649677,-1.1713430341599453,3.067058131253242,0.8394016868466264 3193 Copii coated er to golgi transport vesicle 15 31 3.1412672315575443 0.0016821846582339 Q13190,P49755,Q12907,P10321,P53634,Q9Y6Y8,P04439,Q9UBR2,Q9Y282,Q9BVK6,P55735,Q9Y3A6,P05067,Q15363,Q9Y3B3 Localization GO Cellular component msigdb_gocc 354,417,490,455,487,476,233,244,85,444,440,513,438,29,30 798,1394,2137,1355,1574,2447,1194,942,1497,233,438,455,867,417,487,2321,440,490,354,29,998,693,1211,444,523,244,2978,85,513,30,476 0.40652433044515934,0.009638014956759703,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.5955921179420027,0.12580968009238108,0.30200233977580343,-0.03822288271037234,1.446271558144171,0.8907287812193003,0.8566305867164241,0.36520852896444506,0.9243562959106226,0.8045775073895869,-0.5092252179873332,0.8907287812193003,0.8045775073895869,1.0543605595517835,3.078186020550252,0.259018664523886,0.5267030007716262,0.12580968009238108,0.8907287812193003,0.7514043268649677,1.4329036514563958,-1.1713430341599453,2.4339675988258307,0.7692555416447295,3.067058131253242,0.8394016868466264 3193 Transition metal ion transport 7 14 3.140922788977769 0.0016841642628957 Q15043,P02786,O75027,Q8TAD4,O15173,Q9HC07,Q9HD20 Processes and pathways GO Biological process msigdb_gobp 256,265,170,105,76,146,87 76,170,265,777,994,1625,2008,256,306,105,1383,879,146,87 2.5057902110255577,1.744645033106282,1.3648314259575298,0.42694183408394704,0.259018664523886,-0.11157482962869282,-0.31690808027229783,1.392310058750564,1.207423100369303,2.2812210779922095,0.03326476765043723,0.36520852896444506,1.9009921408923331,2.4176108705977826 3193 Inorganic anion transport 11 27 3.1361324902638024 0.0017119184658764 P08183,P21796,Q9NW15,Q9C0H2,P45880,Q9Y277,Q9UBX3,Q9Y6M7,P30536,Q9UHG3,P51798 Processes and pathways GO Biological process msigdb_gobp 129,7,168,13,15,247,54,151,58,59,184 2964,619,129,3092,7,58,888,15,3156,184,1854,636,1111,870,256,1921,929,474,475,13,1928,168,54,59,247,2443,151 -1.1713430341599453,0.6038310370230041,2.0361169935164405,-1.5417758052175927,3.5491802513502524,2.6556741514333573,0.3443061993948582,3.285196134499565,-2.0464349065431278,1.6738619652882785,-0.23818692761586824,0.5847653265563068,0.19322985148629535,0.36520852896444506,1.392310058750564,-0.26419124276665046,0.32323817115644027,0.8394016868466264,0.8394016868466264,3.351325980333631,-0.26419124276665046,1.7791593908234755,2.732890881137026,2.6556741514333573,1.419454626258951,-0.5665281275626076,1.8465093473865353 3193 Trans golgi network 25 67 3.1361287610470523 0.0017119402352587 P53365,P20645,Q7Z6M1,P61026,Q96A57,Q9HC07,O15127,Q9H4A6,P56377,Q9Y5X1,Q8N2H4,P05067,O15126,P11717,Q7Z3C6,O14828,Q9UID3,Q969E2,O60499,O00443,Q4J6C6,O75592,Q9BTU6,P04062,P53367 Localization GO Cellular component msigdb_gocc 261,633,394,637,143,146,274,426,545,308,182,438,436,568,471,462,615,228,103,350,235,620,641,122,248 350,462,436,274,1705,1492,103,1396,2307,620,122,438,1990,568,633,2956,1847,2815,1897,777,1454,1360,261,248,545,2233,1901,637,1247,833,994,1625,1906,1910,1407,2511,838,2157,235,1211,1514,471,394,817,182,1214,1638,1215,1519,228,143,1347,1824,641,1307,666,426,1183,1974,146,2292,707,615,1603,3137,855,308 1.0543605595517835,0.8394016868466264,0.8907287812193003,1.3229726085415559,-0.16155054834083413,-0.03822288271037234,2.2812210779922095,0.009638014956759703,-0.5092252179873332,0.6038310370230041,2.153135324237049,0.8907287812193003,-0.31690808027229783,0.6786968138424812,0.5847653265563068,-1.1364774707508174,-0.23818692761586824,-0.934824649241834,-0.26419124276665046,0.42694183408394704,-0.014190283332690111,0.03326476765043723,1.3786129091151909,1.4059236947909328,0.7153141117668748,-0.4529950413267082,-0.26419124276665046,0.5847653265563068,0.10296255264400622,0.38594722827302785,0.259018664523886,-0.11157482962869282,-0.26419124276665046,-0.26419124276665046,0.009638014956759703,-0.6249367779380635,0.38594722827302785,-0.39780592754705757,1.446271558144171,0.12580968009238108,-0.03822288271037234,0.8394016868466264,0.9739374379111466,0.40652433044515934,1.6858254775131012,0.12580968009238108,-0.11157482962869282,0.12580968009238108,-0.03822288271037234,1.472767115384539,1.9117156067218775,0.0566926794738131,-0.21241421080737602,0.5847653265563068,0.07992440556882748,0.5655565678430635,0.9243562959106226,0.1484683010782358,-0.2904304927178063,1.9009921408923331,-0.4809780479553145,0.5070546681307051,0.6227553904440447,-0.08691226787820137,-1.8273246014917721,0.38594722827302785,1.207423100369303 3193 Intrinsic component of mitochondrial inner membrane 19 30 3.1318267692070165 0.0017372234454593 O60830,Q99595,O43819,Q6P4A7,Q9NVH1,Q16891,Q9HC21,P17152,Q5XKP0,Q96NB2,Q9Y2R0,Q9H3K2,Q15070,Q13505,Q6UXV4,Q9Y512,Q9BUR5,O14925,Q16134 Localization GO Cellular component msigdb_gocc 0,3,514,142,270,660,405,529,549,677,44,302,48,51,449,332,335,211,613 211,514,0,1610,1026,529,3155,2614,1111,51,48,613,660,1295,549,142,449,876,677,3,335,302,879,2387,405,270,698,44,1019,332 1.5376396248754793,0.7514043268649677,4.042548479567164,-0.11157482962869282,0.23726642403703146,0.7334243460639536,-2.0464349065431278,-0.7146987125093559,0.19322985148629535,2.746560633651398,2.800152733484291,0.6227553904440447,0.5655565678430635,0.07992440556882748,0.7153141117668748,1.9117156067218775,0.8737391734444331,0.36520852896444506,0.5462030417796385,3.6753208773984025,1.1167917984678513,1.2221896821440608,0.36520852896444506,-0.5377405503528547,0.9575234066599015,1.3509647782580774,0.5267030007716262,2.8520707218101506,0.259018664523886,1.1321439407679112 3193 Hydrolase activity acting on glycosyl bonds 14 27 3.128762037472628 0.0017554441012497 P54802,P10253,O75503,P06865,P06280,P16278,Q16706,P17900,O60476,P04066,O60502,P04062,Q9BTY2,O43598 Functions GO Molecular function msigdb_gomf 166,102,104,293,298,11,362,234,398,400,52,122,250,446 2086,446,398,52,104,122,400,298,293,726,102,2676,11,234,1320,3119,1240,1358,166,2050,517,1726,362,1114,2756,250,793 -0.37059222129993374,0.8737391734444331,0.9575234066599015,2.7397396070190534,2.2812210779922095,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,2.2900460179099036,-0.7760255732552376,3.418959561273887,1.446271558144171,0.0566926794738131,-1.7020688805675812,0.10296255264400622,0.03326476765043723,1.7791593908234755,-0.3436274762646461,0.7514043268649677,-0.16155054834083413,1.0384916258428032,0.19322985148629535,-0.8385853324054076,1.4059236947909328,0.42694183408394704 3193 Glycoside hydrolase superfamily [IPR017853] 8 14 3.124483784334367 0.0017811733900909 P10253,P54802,P06865,P06280,P16278,O60502,P04062,Q9BTY2 Sequence InterPro Superfamily interpro_homologous_superfamily 102,166,293,298,11,52,122,250 52,122,400,298,293,726,727,102,11,1358,166,1726,250,1307 2.7397396070190534,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,0.46730587199900714,2.2900460179099036,3.418959561273887,0.03326476765043723,1.7791593908234755,-0.16155054834083413,1.4059236947909328,0.07992440556882748 3193 Steroid binding 10 19 3.1104486571240915 0.001868033677767 P35610,P04062,P21796,Q14849,Q14108,P45880,O15173,O00264,P30536,P38435 Functions GO Molecular function msigdb_gomf 288,122,7,74,14,15,76,371,58,255 371,858,76,2311,122,712,2736,7,1847,2640,58,288,255,15,457,14,74,1429,1738 1.006432544850282,0.36520852896444506,2.5057902110255577,-0.5092252179873332,2.153135324237049,0.48725623745593405,-0.8385853324054076,3.5491802513502524,-0.23818692761586824,-0.7452104629394918,2.6556741514333573,1.280324185022697,1.392310058750564,3.285196134499565,0.8566305867164241,3.309160878702859,2.536807538431712,0.009638014956759703,-0.16155054834083413 3193 Sphingolipid metabolism 8 10 3.0718662479958008 0.0021272502039817 Q06136,P07602,O95470,P17900,Q16880,Q13510,O15269,P04062 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 99,72,171,234,273,116,303,122 303,1060,171,122,72,234,99,116,273,347 1.207423100369303,0.21533758545793177,1.744645033106282,2.153135324237049,2.5672903217950718,1.446271558144171,2.3075717767503545,2.1998773817605315,1.3370121237135937,1.0857828718447309 3193 Liposaccharide metabolic process 10 15 3.05906320791883 0.0022203029902116 P06865,P06280,P16278,P17900,Q9H490,Q16880,P04066,Q99805,Q8NBX0,P04062 Processes and pathways GO Biological process msigdb_gobp 293,298,11,234,368,273,400,367,21,122 1166,122,400,298,293,726,11,234,273,21,519,1683,1971,367,368 0.1484683010782358,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,3.418959561273887,1.446271558144171,1.3370121237135937,3.148622465340775,0.7514043268649677,-0.13645324700708894,-0.2904304927178063,1.0225160037257737,1.0225160037257737 3193 Sterol metabolic process 19 40 3.056047508348796 0.0022427571646124 Q9BQE5,P49748,Q14739,Q14534,Q16850,P35610,Q15800,Q15125,Q8WTV0,P16435,P05067,Q15392,Q14849,O75845,P48449,Q9UBM7,Q9UKR5,P04035,P04062 Processes and pathways GO Biological process msigdb_gobp 6,391,147,403,158,288,35,294,43,299,438,63,74,224,226,370,115,245,122 858,224,2311,1787,245,122,438,1709,2401,299,2607,3113,288,581,582,3000,226,391,1455,2746,457,1952,2825,2913,403,147,74,1411,294,2874,63,921,35,158,2328,43,6,370,1695,115 0.36520852896444506,1.4858962903240147,-0.5092252179873332,-0.21241421080737602,1.419454626258951,2.153135324237049,0.8907287812193003,-0.16155054834083413,-0.5665281275626076,1.2368621349000533,-0.7146987125093559,-1.661294066844009,1.280324185022697,0.6601866548649779,0.6601866548649779,-1.2422071670625843,1.4858962903240147,0.9739374379111466,-0.014190283332690111,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,2.536807538431712,0.009638014956759703,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.5092252179873332,2.871125247428219,3.5925647235517952,1.0225160037257737,-0.13645324700708894,2.2182584184461103 3193 Golgi apparatus subcompartment 37 92 3.0519273498331807 0.0022737712616676 P20645,P53365,Q7Z6M1,P61026,P51572,Q96A57,Q9HC07,O15127,O00461,Q15363,Q9H4A6,P56377,Q96L58,Q9Y5X1,Q8N2H4,Q8WVQ1,P05067,O15126,P11717,Q12893,Q7Z3C6,O14828,Q9UID3,O95249,Q969E2,P04062,O60499,O00443,Q16706,Q10471,Q4J6C6,P04439,O75592,Q10713,Q9BTU6,Q9Y3A3,P53367 Localization GO Cellular component msigdb_gocc 633,261,394,637,141,143,146,274,28,29,426,545,291,308,182,311,438,436,568,325,471,462,615,348,228,122,103,350,362,489,235,233,620,497,641,252,248 350,28,1099,462,436,274,1705,1492,103,1396,2137,2307,620,348,2185,122,233,438,1990,3092,568,633,2956,1847,2815,1897,2503,777,1454,141,1360,261,248,545,2233,1901,637,1247,833,994,1625,1906,2748,489,1910,497,1407,325,2511,838,674,2157,29,362,235,1211,1514,471,394,817,182,1048,1214,1259,311,1638,1215,1519,228,143,291,1347,1824,2599,2381,641,1307,666,426,1183,1974,146,2292,707,615,1603,3137,855,1700,986,252,308 1.0543605595517835,3.078186020550252,0.19322985148629535,0.8394016868466264,0.8907287812193003,1.3229726085415559,-0.16155054834083413,-0.03822288271037234,2.2812210779922095,0.009638014956759703,-0.39780592754705757,-0.5092252179873332,0.6038310370230041,1.070123936480939,-0.4252722805882104,2.153135324237049,1.446271558144171,0.8907287812193003,-0.31690808027229783,-1.5417758052175927,0.6786968138424812,0.5847653265563068,-1.1364774707508174,-0.23818692761586824,-0.934824649241834,-0.26419124276665046,-0.6249367779380635,0.42694183408394704,-0.014190283332690111,1.9223825076951602,0.03326476765043723,1.3786129091151909,1.4059236947909328,0.7153141117668748,-0.4529950413267082,-0.26419124276665046,0.5847653265563068,0.10296255264400622,0.38594722827302785,0.259018664523886,-0.11157482962869282,-0.26419124276665046,-0.8385853324054076,0.8045775073895869,-0.26419124276665046,0.7869794546562088,0.009638014956759703,1.1321439407679112,-0.6249367779380635,0.38594722827302785,0.5462030417796385,-0.39780592754705757,3.078186020550252,1.0384916258428032,1.446271558144171,0.12580968009238108,-0.03822288271037234,0.8394016868466264,0.9739374379111466,0.40652433044515934,1.6858254775131012,0.23726642403703146,0.12580968009238108,0.10296255264400622,1.1925614229636166,-0.11157482962869282,0.12580968009238108,-0.03822288271037234,1.472767115384539,1.9117156067218775,1.2659284528512882,0.0566926794738131,-0.21241421080737602,-0.6844855875507391,-0.5377405503528547,0.5847653265563068,0.07992440556882748,0.5655565678430635,0.9243562959106226,0.1484683010782358,-0.2904304927178063,1.9009921408923331,-0.4809780479553145,0.5070546681307051,0.6227553904440447,-0.08691226787820137,-1.8273246014917721,0.38594722827302785,-0.13645324700708894,0.28059656391052684,1.4059236947909328,1.207423100369303 3193 Molecular transducer activity 7 31 3.0504452387377308 0.0022850234572551 Q15629,Q9BUN8,P30536,Q8WTV0,Q14108,O15173,Q99720 Functions GO Molecular function msigdb_gomf 64,165,58,43,14,76,26 1236,858,76,2351,1890,568,633,58,1898,1068,1401,1905,835,690,950,14,839,64,899,186,422,1763,43,930,1736,359,26,165,2174,2128,853 0.10296255264400622,0.36520852896444506,2.5057902110255577,-0.5377405503528547,-0.26419124276665046,0.6786968138424812,0.5847653265563068,2.6556741514333573,-0.26419124276665046,0.21533758545793177,0.009638014956759703,-0.26419124276665046,0.38594722827302785,0.5267030007716262,0.30200233977580343,3.309160878702859,0.38594722827302785,2.62670988147732,0.3443061993948582,1.6738619652882785,0.9243562959106226,-0.18686982059176915,2.871125247428219,0.32323817115644027,-0.16155054834083413,1.0543605595517835,3.0892345539041384,1.7905380137060627,-0.39780592754705757,-0.37059222129993374,0.38594722827302785 3193 Golgi membrane 68 135 3.047661023422372 0.0023062992553668 P24390,Q7LGA3,Q8IV08,P61026,O15260,Q9Y3E0,Q9BXS5,P51572,Q14108,O60476,O95721,Q9HC07,O43505,P61923,P61019,P62820,O00461,Q15363,Q9Y3B3,P42345,Q15382,Q9H7Z7,P56377,Q96L58,O43731,Q9H4A6,P49755,Q6ZRP7,Q14789,Q8IZA0,Q08AM6,Q8N2H4,Q9BVK6,O95295,Q9Y678,P35613,P11717,Q15392,Q8NF37,Q12893,P10321,P52292,Q9BUR5,Q96S66,Q8NCH0,Q7Z3C6,Q9Y282,Q9UM00,O95197,O95249,O15498,Q13190,Q9P2W9,Q8TB61,O15258,O60499,Q12907,Q16706,Q10471,Q86Y82,P04439,Q99640,Q8N6H7,Q92896,Q10713,Q9Y371,P53367,Q9NTJ5 Localization GO Cellular component msigdb_gocc 2,131,262,637,259,396,666,141,14,398,399,146,275,657,656,531,28,29,30,409,548,427,545,291,36,426,417,295,674,173,690,182,444,686,710,317,568,63,318,325,455,333,335,474,82,471,85,214,86,348,604,354,100,101,351,103,490,362,489,627,233,365,500,243,497,512,248,645 912,28,2635,1274,798,1394,351,259,604,275,1837,36,1705,398,103,2137,1574,86,348,686,399,1497,233,2352,3092,455,863,568,1847,2,990,317,2406,1897,409,1069,1241,867,2360,417,777,141,3156,333,248,2504,2267,545,2233,2147,1622,1901,656,637,1247,657,1903,531,833,994,2748,690,489,1910,497,325,490,354,760,14,674,2776,2157,29,548,63,998,362,2417,1143,295,131,471,1962,627,926,262,173,182,500,1679,82,318,101,1048,786,1214,1259,1215,1519,243,291,1347,474,365,335,444,3089,666,961,3062,426,427,1008,1183,146,1057,645,707,2256,100,1933,1602,1696,2923,3137,214,85,986,2992,3104,512,30,396,710 0.32323817115644027,3.078186020550252,-0.7452104629394918,0.07992440556882748,0.40652433044515934,0.009638014956759703,1.0543605595517835,1.3786129091151909,0.6227553904440447,1.3229726085415559,-0.23818692761586824,2.96913415144942,-0.16155054834083413,0.9575234066599015,2.2812210779922095,-0.39780592754705757,-0.08691226787820137,2.4176108705977826,1.070123936480939,0.5267030007716262,0.9575234066599015,-0.03822288271037234,1.446271558144171,-0.5377405503528547,-1.5417758052175927,0.8566305867164241,0.36520852896444506,0.6786968138424812,-0.23818692761586824,3.7462657069794476,0.259018664523886,1.162548846164761,-0.5665281275626076,-0.26419124276665046,0.9409967716069575,0.21533758545793177,0.10296255264400622,0.36520852896444506,-0.5377405503528547,0.9243562959106226,0.42694183408394704,1.9223825076951602,-2.0464349065431278,1.1167917984678513,1.4059236947909328,-0.6249367779380635,-0.4809780479553145,0.7153141117668748,-0.4529950413267082,-0.39780592754705757,-0.11157482962869282,-0.26419124276665046,0.5655565678430635,0.5847653265563068,0.10296255264400622,0.5655565678430635,-0.26419124276665046,0.7334243460639536,0.38594722827302785,0.259018664523886,-0.8385853324054076,0.5267030007716262,0.8045775073895869,-0.26419124276665046,0.7869794546562088,1.1321439407679112,0.8045775073895869,1.0543605595517835,0.44720170401297976,3.309160878702859,0.5462030417796385,-0.8703399800828923,-0.39780592754705757,3.078186020550252,0.7153141117668748,2.6339966056994,0.259018664523886,1.0384916258428032,-0.5665281275626076,0.17094088359372295,1.2514414118114898,1.985222235335816,0.8394016868466264,-0.2904304927178063,0.6038310370230041,0.32323817115644027,1.3786129091151909,1.7330122185385242,1.6858254775131012,0.7869794546562088,-0.13645324700708894,2.4420909128633217,1.162548846164761,2.2988294808347165,0.23726642403703146,0.42694183408394704,0.12580968009238108,0.10296255264400622,0.12580968009238108,-0.03822288271037234,1.4329036514563958,1.2659284528512882,0.0566926794738131,0.8394016868466264,1.0384916258428032,1.1167917984678513,0.8907287812193003,-1.5028434769808663,0.5655565678430635,0.30200233977580343,-1.3886547156284181,0.9243562959106226,0.9243562959106226,0.259018664523886,0.1484683010782358,1.9009921408923331,0.23726642403703146,0.5847653265563068,0.5070546681307051,-0.4529950413267082,2.3075717767503545,-0.26419124276665046,-0.08691226787820137,-0.13645324700708894,-1.0678476456651755,-1.8273246014917721,1.5376396248754793,2.4339675988258307,0.28059656391052684,-1.2065841027857491,-1.581156126510372,0.7692555416447295,3.067058131253242,0.9739374379111466,0.5070546681307051 3193 Tetrapyrrole binding 10 16 3.031004896762029 0.0024374129493376 P30519,O43169,O15173,P09601,O00264,Q8WUJ1,Q7KZN9,Q6UW02,Q16850,Q9H7Z7 Functions GO Molecular function msigdb_gomf 69,46,76,17,371,179,150,189,158,427 371,76,46,752,17,1357,69,456,158,189,150,179,1217,679,427,2920 1.006432544850282,2.5057902110255577,2.832792341598909,0.44720170401297976,3.250973747172662,0.03326476765043723,2.589810382359061,0.8566305867164241,1.8243030426289284,1.661830514045592,1.8465093473865353,1.6977216604154457,0.12580968009238108,0.5462030417796385,0.9243562959106226,-1.0678476456651755 3193 Endoplasmic reticulum to golgi vesicle mediated transport 24 66 3.0241283682876814 0.0024935061217383 P24390,Q9NR31,P51572,P61019,P62820,Q15363,Q9Y3B3,O43731,P49755,Q15437,Q9BVK6,P55735,Q9Y678,Q9Y6Y8,Q8NHH9,Q9Y282,Q9HCU5,O95249,O15498,Q13190,Q9P2W9,Q12907,Q9Y3A6,Q96PC5 Processes and pathways GO Biological process msigdb_gobp 2,523,141,656,531,29,30,36,417,693,444,440,710,476,472,85,744,348,604,354,100,490,513,386 1532,2635,798,1394,604,2304,1837,36,2137,1355,1574,2447,348,2496,1194,942,1169,2,990,1069,867,417,141,1360,2504,2267,2321,2969,440,656,531,490,354,1723,29,998,693,1172,737,1633,1116,472,1259,1215,1681,386,444,961,1384,744,1057,904,523,2256,100,1933,2978,1979,85,986,795,513,30,1879,710,476 -0.062462590653624604,-0.7452104629394918,0.40652433044515934,0.009638014956759703,0.6227553904440447,-0.5092252179873332,-0.23818692761586824,2.96913415144942,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.5955921179420027,1.070123936480939,-0.6249367779380635,0.12580968009238108,0.30200233977580343,0.1484683010782358,3.7462657069794476,0.259018664523886,0.21533758545793177,0.36520852896444506,0.9243562959106226,1.9223825076951602,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,-1.1713430341599453,0.8907287812193003,0.5655565678430635,0.7334243460639536,0.8045775073895869,1.0543605595517835,-0.16155054834083413,3.078186020550252,0.259018664523886,0.5267030007716262,0.1484683010782358,0.46730587199900714,-0.11157482962869282,0.19322985148629535,0.8394016868466264,0.10296255264400622,0.12580968009238108,-0.13645324700708894,0.9902400838282385,0.8907287812193003,0.30200233977580343,0.03326476765043723,0.46730587199900714,0.23726642403703146,0.3443061993948582,0.7514043268649677,-0.4529950413267082,2.3075717767503545,-0.26419124276665046,-1.1713430341599453,-0.2904304927178063,2.4339675988258307,0.28059656391052684,0.42694183408394704,0.7692555416447295,3.067058131253242,-0.23818692761586824,0.5070546681307051,0.8394016868466264 3193 Cholesterol metabolism with bloch and kandutschrussell pathways 12 25 2.992885157959284 0.0027635371730956 P35610,O75845,P48449,Q15800,Q15125,O00767,Q9UBM7,Q14739,O95864,P04035,Q15392,Q16850 Processes and pathways WikiPathways msigdb_wp 288,224,226,35,294,360,370,147,374,245,63,158 360,1985,224,1750,374,245,2401,1579,288,581,226,1401,2746,2825,2913,403,147,294,2874,63,921,35,158,1828,370 1.0384916258428032,-0.31690808027229783,1.4858962903240147,-0.18686982059176915,1.006432544850282,1.419454626258951,-0.5665281275626076,-0.08691226787820137,1.280324185022697,0.6601866548649779,1.4858962903240147,0.009638014956759703,-0.8385853324054076,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.21241421080737602,1.0225160037257737 3193 Aminoglycan metabolic process 9 12 2.990011128976384 0.002789672829732 Q96L58,Q7LGA3,P54802,P06865,P16278,P04066,Q8NCH0,O43505,P15586 Processes and pathways GO Biological process msigdb_gobp 291,131,166,293,11,400,82,275,310 275,485,400,293,726,310,11,166,1625,131,82,291 1.3229726085415559,0.8045775073895869,0.9575234066599015,1.2514414118114898,0.46730587199900714,1.1925614229636166,3.418959561273887,1.7791593908234755,-0.11157482962869282,1.985222235335816,2.4420909128633217,1.2659284528512882 3193 Nuclear outer membrane endoplasmic reticulum membrane network 130 285 2.98092307346895 0.0028738097286382 P24390,Q9P035,Q9BQE5,Q92643,P43307,Q13724,Q14108,P09601,Q15005,P61619,O75915,Q99720,Q8N0U8,Q15363,Q9Y3B3,Q15382,Q5BJF2,Q15800,O43731,Q8N511,O43865,Q9H2M9,Q15392,Q15629,P30519,Q14849,O75844,Q9Y282,Q9HD20,O95197,Q86UE4,Q06136,Q9P2W9,Q8TB61,Q9NQC3,Q86XL3,Q03518,Q9UKR5,P51648,O60725,P51572,Q14739,Q96KC8,Q9UBV2,Q9BRR6,Q16850,Q96G23,Q9BUN8,O95470,P67812,Q86YN1,Q5VUD6,Q9Y5M8,Q9BV10,Q8N2K0,P46977,Q9UM00,Q96GC9,P07099,O75845,P48449,Q8TCT9,Q07065,Q15904,Q53GQ0,P04439,P04035,Q9Y4P3,P38435,Q8IV08,O15260,P50402,Q12959,Q96RL7,Q9NZ08,Q96A33,Q70UQ0,P57088,P35610,Q15125,P16615,P16435,Q6NUM9,O15269,Q8WVQ1,Q9BT22,P35613,Q8NF37,Q2TAA5,Q9UBU6,Q6NUQ4,Q9NPA0,P52292,Q9BUR5,Q92604,Q9NZ01,Q99442,Q13190,O00767,Q99640,Q9H490,Q9UBM7,O00264,O43852,O95864,Q6UWP7,Q96PC5,Q9Y5L0,Q14534,A1L0T0,P42345,Q9H3N1,P49755,Q12981,O95674,Q9BVK6,Q99735,P55735,P06493,P10321,O76024,Q96S66,Q8NHH9,Q7Z3C6,P62942,Q12907,Q86UL3,Q10471,Q9Y3A6,Q8N5M9 Localization GO Cellular component msigdb_gocc 2,524,6,519,10,517,14,17,533,530,528,26,27,29,30,548,32,35,36,49,553,577,63,64,69,74,81,85,87,86,92,99,100,101,113,112,111,115,130,140,141,147,148,154,153,158,159,165,171,172,177,178,183,199,203,206,214,220,222,224,226,227,229,230,236,233,245,253,255,262,259,266,279,285,287,284,283,282,288,294,300,299,301,303,311,316,317,318,326,331,334,336,333,335,343,347,359,354,360,365,368,370,371,372,374,385,386,397,403,407,409,425,417,420,415,444,442,440,439,455,454,474,472,471,481,490,492,489,513,511 617,407,1352,371,1098,2605,360,2635,798,771,1572,2261,1394,259,303,1060,2304,800,36,372,553,1985,1396,140,1166,1355,1574,81,224,528,454,1317,2734,2311,1888,2447,86,2496,171,1194,942,1750,415,374,2036,1787,1497,245,233,687,1030,439,3105,222,2314,2352,17,455,2452,299,300,1066,1447,1847,2931,2,1946,3087,865,2843,2718,69,3043,2144,1579,990,288,317,581,255,1896,409,1451,10,206,1069,226,1285,1241,867,1582,417,1757,266,756,141,130,1360,333,2504,2267,2321,2969,440,282,3059,2147,1622,1544,656,637,1247,1545,530,713,657,2823,810,2150,481,2461,172,2238,1667,111,1954,99,229,489,1365,490,279,420,354,1668,2273,517,14,872,2365,838,403,147,74,533,1549,814,2240,294,29,548,63,998,693,64,921,35,230,2417,158,326,236,32,661,1172,178,1336,301,737,334,954,385,283,875,471,92,492,1338,112,177,262,2831,1732,27,203,49,2373,511,1554,318,1003,472,1175,2067,101,1341,587,2594,227,1118,929,1865,1259,311,877,1818,343,519,2332,1683,1342,284,1640,1050,159,220,1969,575,148,386,285,1971,474,359,365,26,442,6,153,2025,2120,316,631,165,335,199,1054,3142,444,1429,1738,1973,961,577,425,368,1008,1092,744,87,880,336,113,645,682,707,347,287,524,909,2256,2128,100,1933,1602,370,331,154,853,115,3137,214,2490,85,938,884,513,30,2963,253,397,183,3160,710,1833 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3193 Endoplasmic reticulum organization 20 40 2.977755701026642 0.0029036732581819 P61026,Q5J8M3,P61619,Q00765,Q96A33,Q15363,P57088,Q12981,Q9H2M9,P46379,Q15629,Q9NPA0,Q8NHH9,O95197,Q9P2W9,Q12907,Q9NQC3,O43681,A0FGR8,Q8N5M9 Processes and pathways GO Biological process msigdb_gobp 637,661,530,546,284,29,282,420,577,62,64,336,472,86,100,490,113,619,617,511 617,2949,1098,1440,1394,619,1747,2447,86,2496,62,867,282,637,530,546,490,420,1549,814,29,64,661,1172,2280,511,1554,1003,472,284,2120,577,1384,880,336,113,707,909,2256,100 0.6038310370230041,-1.1364774707508174,0.19322985148629535,-0.014190283332690111,0.009638014956759703,0.6038310370230041,-0.18686982059176915,-0.5955921179420027,2.4176108705977826,-0.6249367779380635,2.6339966056994,0.36520852896444506,1.2946295225860096,0.5847653265563068,0.7334243460639536,0.7153141117668748,0.8045775073895869,0.9243562959106226,-0.062462590653624604,0.40652433044515934,3.078186020550252,2.62670988147732,0.5655565678430635,0.1484683010782358,-0.4809780479553145,0.7692555416447295,-0.062462590653624604,0.259018664523886,0.8394016868466264,1.2946295225860096,-0.37059222129993374,0.6786968138424812,0.03326476765043723,0.36520852896444506,1.1167917984678513,2.2364631467360248,0.5070546681307051,0.3443061993948582,-0.4529950413267082,2.3075717767503545 3193 Steroid metabolic process 25 67 2.9767773542494567 0.0029129546838013 Q9BQE5,P49748,Q14739,Q14534,Q16850,P35610,Q15800,Q15125,Q8WTV0,P16435,O95470,P30536,P05067,Q15392,Q14849,Q99538,O75845,P48449,Q53GQ0,Q9UBM7,Q9UKR5,Q13510,P04035,P04062,P38435 Processes and pathways GO Biological process msigdb_gobp 6,391,147,403,158,288,35,294,43,299,171,58,438,63,74,346,224,226,236,370,115,116,245,122,255 966,858,224,2311,171,1787,245,122,712,438,3184,1709,2401,2842,299,1847,2640,2607,3112,515,58,3113,288,581,255,582,3000,226,391,2744,1324,1455,2746,457,1952,2825,2463,116,2913,403,147,74,1411,294,2874,63,1671,1463,921,35,158,236,2328,784,550,43,2975,346,3008,6,1738,3062,370,1695,1437,115,2762 0.28059656391052684,0.36520852896444506,1.4858962903240147,-0.5092252179873332,1.744645033106282,-0.21241421080737602,1.419454626258951,2.153135324237049,0.48725623745593405,0.8907287812193003,-3.200072430029395,-0.16155054834083413,-0.5665281275626076,-0.9675653554604676,1.2368621349000533,-0.23818692761586824,-0.7452104629394918,-0.7146987125093559,-1.661294066844009,0.7514043268649677,2.6556741514333573,-1.661294066844009,1.280324185022697,0.6601866548649779,1.392310058750564,0.6601866548649779,-1.2422071670625843,1.4858962903240147,0.9739374379111466,-0.8385853324054076,0.0566926794738131,-0.014190283332690111,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-0.5955921179420027,2.1998773817605315,-1.0678476456651755,0.9575234066599015,1.8684775279957868,2.536807538431712,0.009638014956759703,1.2514414118114898,-1.00064563472387,2.6339966056994,-0.13645324700708894,-0.014190283332690111,0.32323817115644027,2.975065555239934,1.8243030426289284,1.446271558144171,-0.5092252179873332,0.42694183408394704,0.7153141117668748,2.871125247428219,-1.1713430341599453,1.0857828718447309,-1.2422071670625843,3.5925647235517952,-0.16155054834083413,-1.3886547156284181,1.0225160037257737,-0.13645324700708894,0.009638014956759703,2.2182584184461103,-0.8385853324054076 3193 membrane trafficking regulatory protein 6 18 2.9450686133394437 0.0032288305161467 P24390,O43731,Q8WTV0,P13473,Q14108,O43760 Functions Panther Protein class panther_protein_class 2,36,43,204,14,125 2604,1314,36,125,2496,309,204,2,14,2156,2157,43,1259,819,1149,1221,2256,720 -0.7146987125093559,0.0566926794738131,2.96913415144942,2.09550477869399,-0.6249367779380635,1.1925614229636166,1.5630573692038123,3.7462657069794476,3.309160878702859,-0.39780592754705757,-0.39780592754705757,2.871125247428219,0.10296255264400622,0.40652433044515934,0.17094088359372295,0.12580968009238108,-0.4529950413267082,0.48725623745593405 3193 Intra golgi and retrograde golgi to er traffic 51 99 2.944350021039892 0.0032363375955049 P24390,P20645,P53365,Q7Z6M1,O15260,Q14203,P04350,O60476,O95721,Q9BVA1,P61923,P62820,O00461,Q15363,Q9Y3B3,Q12756,Q8IWJ2,O43731,P49755,Q12981,Q13409,Q15042,Q13561,O14653,Q13509,Q9H2M9,Q8N2H4,Q9BVK6,Q9Y678,P11717,Q9Y496,P68371,P84085,P83436,P43034,P52732,Q9UID3,Q6NUQ1,O95249,Q13885,O15498,Q13190,Q9P2W9,O60499,Q9UJW0,Q16706,Q10471,Q8N6H7,O75935,Q5VZE5,Q9BUF5 Processes and pathways Reactome Pathways msigdb_reactome 2,633,261,394,259,639,390,398,399,404,657,531,28,29,30,778,817,36,417,420,812,814,813,798,691,577,182,444,710,568,857,320,458,833,583,596,615,737,348,612,604,354,100,103,231,362,489,500,240,242,378 1352,1233,28,2635,798,259,604,1101,2304,36,398,103,1131,1574,240,2312,1535,348,399,390,568,1169,633,2,972,990,1897,583,2503,2865,1754,1069,417,596,2266,261,2504,2267,2547,831,657,531,1624,320,2824,833,458,2152,1511,489,778,420,354,812,691,813,612,639,1913,2325,814,3004,29,362,242,737,394,817,182,500,1679,1048,1118,1214,1215,2759,1347,1927,2780,2168,378,404,444,2170,1007,1928,961,577,1183,880,2295,100,1933,615,231,30,857,710,1162 0.03326476765043723,0.10296255264400622,3.078186020550252,-0.7452104629394918,0.40652433044515934,1.3786129091151909,0.6227553904440447,0.19322985148629535,-0.5092252179873332,2.96913415144942,0.9575234066599015,2.2812210779922095,0.17094088359372295,-0.08691226787820137,1.4329036514563958,-0.5092252179873332,-0.062462590653624604,1.070123936480939,0.9575234066599015,0.9739374379111466,0.6786968138424812,0.1484683010782358,0.5847653265563068,3.7462657069794476,0.28059656391052684,0.259018664523886,-0.26419124276665046,0.6601866548649779,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.9243562959106226,0.6415400506909451,-0.4809780479553145,1.3786129091151909,-0.6249367779380635,-0.4809780479553145,-0.6545664545020534,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,-0.934824649241834,0.38594722827302785,0.8566305867164241,-0.39780592754705757,-0.03822288271037234,0.8045775073895869,0.42694183408394704,0.9243562959106226,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.6227553904440447,0.5847653265563068,-0.26419124276665046,-0.5092252179873332,0.40652433044515934,-1.2422071670625843,3.078186020550252,1.0384916258428032,1.4329036514563958,0.46730587199900714,0.9739374379111466,0.40652433044515934,1.6858254775131012,0.7869794546562088,-0.13645324700708894,0.23726642403703146,0.19322985148629535,0.12580968009238108,0.12580968009238108,-0.8385853324054076,0.0566926794738131,-0.26419124276665046,-0.8703399800828923,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,-0.39780592754705757,0.259018664523886,-0.26419124276665046,0.30200233977580343,0.6786968138424812,0.1484683010782358,0.36520852896444506,-0.4809780479553145,2.3075717767503545,-0.26419124276665046,0.6227553904440447,1.4595591237186676,3.067058131253242,0.38594722827302785,0.5070546681307051,0.17094088359372295 3193 Protein localization 34 73 2.9419204165558583 0.0032618374267203 O60830,P51648,Q99595,P21796,P50402,P28288,Q9NS69,P09601,O75874,Q15388,O75746,Q15067,Q9UJS0,Q8N4H5,O43615,Q13011,Q13505,Q3ZCQ8,A8MXV4,P05067,Q9NR77,P46379,Q9BY49,O75381,Q9Y512,O15228,P12235,O14925,P12236,Q13190,Q8NBU5,Q5JRX3,Q10713,O43808 Processes and pathways Reactome Pathways msigdb_reactome 0,130,3,7,266,515,16,17,277,280,527,421,428,41,414,431,51,557,429,438,61,62,322,193,332,578,338,211,217,354,628,625,497,505 429,1022,966,211,578,414,619,1747,505,0,193,3066,1610,2788,2927,527,277,1316,651,438,1134,752,3184,17,3129,338,217,1654,7,2640,1997,515,3113,3125,3155,973,62,266,1507,130,1324,2409,3059,2102,497,431,354,51,421,280,557,625,2280,41,2832,628,1967,3,3009,322,2253,61,16,698,2256,1697,428,2979,1230,2298,332,1703,1272 0.9076007240012801,0.23726642403703146,0.28059656391052684,1.5376396248754793,0.6601866548649779,0.9243562959106226,0.6038310370230041,-0.18686982059176915,0.7692555416447295,4.042548479567164,1.6375613175769943,-1.426290709801661,-0.11157482962869282,-0.902417991440706,-1.101981072569348,0.7334243460639536,1.3088453672804772,0.0566926794738131,0.5655565678430635,0.8907287812193003,0.17094088359372295,0.44720170401297976,-3.200072430029395,3.250973747172662,-1.7850748625508288,1.1013384647454063,1.5248183397306079,-0.13645324700708894,3.5491802513502524,-0.7452104629394918,-0.31690808027229783,0.7514043268649677,-1.661294066844009,-1.743326090815665,-2.0464349065431278,0.28059656391052684,2.6339966056994,1.3648314259575298,-0.03822288271037234,2.015915696016737,0.0566926794738131,-0.5665281275626076,-1.3886547156284181,-0.37059222129993374,0.7869794546562088,0.9076007240012801,1.0543605595517835,2.746560633651398,0.9243562959106226,1.3088453672804772,0.6970721128067479,0.6038310370230041,-0.4809780479553145,2.8899600348937455,-0.934824649241834,0.6038310370230041,-0.2904304927178063,3.6753208773984025,-1.2422071670625843,1.1473959441543768,-0.4529950413267082,2.6412527563805264,3.2657379732892013,0.5267030007716262,-0.4529950413267082,-0.13645324700708894,0.9243562959106226,-1.1713430341599453,0.12580968009238108,-0.4809780479553145,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Increased bone mineral density 10 24 2.9381590853028654 0.0033016755575667 Q15043,P54802,Q15125,Q13126,Q14108,Q14739,Q9Y4P3,P04062,P51798,Q15392 Drugs and Diseases Human Phenotype Ontology msigdb_hp 256,166,294,73,14,147,253,122,184,63 1708,122,569,916,2956,2681,2818,1285,184,166,2969,2506,2100,73,14,147,256,1810,294,63,1858,319,2339,253 -0.16155054834083413,2.153135324237049,0.6786968138424812,0.32323817115644027,-1.1364774707508174,-0.7760255732552376,-0.934824649241834,0.07992440556882748,1.6738619652882785,1.7791593908234755,-1.1713430341599453,-0.6249367779380635,-0.37059222129993374,2.5597189348802236,3.309160878702859,1.8684775279957868,1.392310058750564,-0.21241421080737602,1.2514414118114898,2.6339966056994,-0.23818692761586824,1.162548846164761,-0.5092252179873332,1.4059236947909328 3193 Carbohydrate derivative transport 10 16 2.935405710886937 0.0033311183201651 Q99808,Q8TB61,P07602,P05141,P61916,Q8WTV0,P12235,Q9HC21,P12236,Q9NZJ7 Processes and pathways GO Biological process msigdb_gobp 321,101,72,361,457,43,338,405,217,191 912,505,361,72,338,217,654,457,835,1112,101,929,43,321,405,191 0.32323817115644027,0.7692555416447295,1.0384916258428032,2.5672903217950718,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.8566305867164241,0.38594722827302785,0.19322985148629535,2.2988294808347165,0.32323817115644027,2.871125247428219,1.1473959441543768,0.9575234066599015,1.6497305064842487 3193 Steroid biosynthesis 10 12 2.916158623911889 0.003543702849432 O75845,P48449,P35610,Q15800,Q15125,P38571,Q9UBM7,Q14534,Q15392,Q16850 Processes and pathways KEGG Pathways msigdb_kegg 224,226,288,35,294,582,370,403,63,158 224,288,581,582,226,403,294,63,921,35,158,370 1.4858962903240147,1.280324185022697,0.6601866548649779,0.6601866548649779,1.4858962903240147,0.9575234066599015,1.2514414118114898,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,1.0225160037257737 3193 Cytochrome complex assembly 9 13 2.9099581365406757 0.0036147717084251 P47985,Q69YU5,P53701,Q6DKK2,O43819,Q9Y2R0,Q15070,Q7KZN9,Q9BSK2 Processes and pathways GO Biological process msigdb_gobp 448,8,456,363,514,44,48,150,212 514,1026,448,456,48,8,363,150,630,1427,212,1230,44 0.7514043268649677,0.23726642403703146,0.8737391734444331,0.8566305867164241,2.800152733484291,3.5371028334084,1.0384916258428032,1.8465093473865353,0.6038310370230041,0.009638014956759703,1.5376396248754793,0.12580968009238108,2.8520707218101506 3193 Metal ion transmembrane transporter activity 15 24 2.904712614287267 0.0036759044619361 Q15043,Q9H2J7,P55011,P61619,Q8TAD4,P16615,P20020,Q9BXP2,P05023,Q9HC07,Q9UM00,Q9HD20,Q9Y6M7,O95202,Q6P4Q7 Functions GO Molecular function msigdb_gomf 256,289,636,530,105,300,580,475,712,146,214,87,151,155,375 155,712,2449,1988,2736,727,300,580,636,530,994,1717,256,375,876,105,1736,475,1973,289,146,87,214,151 1.8243030426289284,0.48725623745593405,-0.5955921179420027,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,1.2368621349000533,0.6601866548649779,0.5847653265563068,0.7334243460639536,0.259018664523886,-0.16155054834083413,1.392310058750564,1.006432544850282,0.36520852896444506,2.2812210779922095,-0.16155054834083413,0.8394016868466264,-0.2904304927178063,1.280324185022697,1.9009921408923331,2.4176108705977826,1.5376396248754793,1.8465093473865353 3193 Proton transmembrane transporter activity 15 34 2.89654624960665 0.0037729502419709 P47985,Q13423,P56385,Q93050,Q9Y487,P05141,P13073,Q96ES6,P12235,P24539,Q7KZN9,Q9UDW1,P00403,O95202,O75964 Functions GO Molecular function msigdb_gomf 448,161,418,138,71,361,136,75,338,181,150,22,216,155,31 2671,31,155,216,361,1134,752,1790,338,136,2092,1846,2639,181,1997,1795,1797,1617,2864,448,3131,3156,1199,418,466,1111,161,150,138,75,1599,22,1980,71 -0.7760255732552376,3.0502155042807657,1.8243030426289284,1.5248183397306079,1.0384916258428032,0.17094088359372295,0.44720170401297976,-0.21241421080737602,1.1013384647454063,1.9329933181047383,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,0.8737391734444331,-1.7850748625508288,-2.0464349065431278,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.19322985148629535,1.801854471157927,1.8465093473865353,1.9329933181047383,2.5291039002629425,-0.08691226787820137,3.143317850644801,-0.2904304927178063,2.582335824717171 3193 Secondary alcohol metabolic process 20 44 2.8880838795056034 0.0038759649706914 Q9BQE5,P49748,Q14739,Q14534,O75874,Q16850,P35610,Q15800,Q15125,Q8WTV0,P16435,P48735,P05067,Q15392,Q14849,O75845,P48449,Q9UBM7,P04035,P04062 Processes and pathways GO Biological process msigdb_gobp 6,391,147,403,277,158,288,35,294,43,299,314,438,63,74,224,226,370,245,122 858,2263,224,277,2311,1787,245,122,438,1709,2401,299,2607,3113,288,581,3000,226,314,391,3058,1507,1455,2746,457,1952,2825,2913,403,147,74,1411,294,2874,63,921,35,158,2328,43,3009,6,370,1695 0.36520852896444506,-0.4809780479553145,1.4858962903240147,1.3088453672804772,-0.5092252179873332,-0.21241421080737602,1.419454626258951,2.153135324237049,0.8907287812193003,-0.16155054834083413,-0.5665281275626076,1.2368621349000533,-0.7146987125093559,-1.661294066844009,1.280324185022697,0.6601866548649779,-1.2422071670625843,1.4858962903240147,1.1776036696350574,0.9739374379111466,-1.3886547156284181,-0.03822288271037234,-0.014190283332690111,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,2.536807538431712,0.009638014956759703,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.5092252179873332,2.871125247428219,-1.2422071670625843,3.5925647235517952,1.0225160037257737,-0.13645324700708894 3193 Mitochondrial respiratory chain complex assembly 16 36 2.886297175080881 0.0038980390304179 P47985,O43676,O95831,Q69YU5,Q9P0J0,Q9Y512,Q9Y2R0,O43819,Q6DKK2,Q15070,O95168,O75306,Q9BRT2,Q9BSK2,Q9H061,Q96CU9 Processes and pathways GO Biological process msigdb_gobp 448,34,194,8,201,332,44,514,363,48,593,205,630,212,57,126 2134,34,514,1443,205,1942,1026,593,2350,194,3070,448,1583,2868,48,2416,1209,8,363,1553,2832,1257,126,630,1427,212,2169,57,1642,719,2175,201,1230,44,332,649 -0.39780592754705757,2.9927281115085713,0.7514043268649677,-0.014190283332690111,1.5503857345605445,-0.2904304927178063,0.23726642403703146,0.6415400506909451,-0.5377405503528547,1.6375613175769943,-1.426290709801661,0.8737391734444331,-0.08691226787820137,-1.00064563472387,2.800152733484291,-0.5665281275626076,0.12580968009238108,3.5371028334084,1.0384916258428032,-0.062462590653624604,-0.934824649241834,0.10296255264400622,2.09550477869399,0.6038310370230041,0.009638014956759703,1.5376396248754793,-0.39780592754705757,2.6699756767430465,-0.11157482962869282,0.48725623745593405,-0.39780592754705757,1.6006322940022837,0.12580968009238108,2.8520707218101506,1.1321439407679112,0.5847653265563068 3193 ER-Golgi transport 21 51 2.878983764067415 0.0039895887278111 P24390,Q9NR31,P51572,P61923,P61019,P62820,Q15363,O43731,P49755,Q12981,Q15437,P55735,Q9Y678,P84085,Q9Y282,O95197,Q9HCU5,O95249,O15498,Q9P2W9,Q8N6H7 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 2,523,141,657,656,531,29,36,417,420,693,440,710,458,85,86,744,348,604,100,500 2635,1394,604,2304,1837,36,2137,1574,2447,86,348,1194,942,1169,2,990,1069,867,417,141,2504,2267,2321,2547,440,656,657,531,458,420,1723,29,998,693,1172,737,1633,1116,500,1679,1259,1681,2168,744,523,100,1933,85,986,795,710 -0.7452104629394918,0.009638014956759703,0.6227553904440447,-0.5092252179873332,-0.23818692761586824,2.96913415144942,-0.39780592754705757,-0.08691226787820137,-0.5955921179420027,2.4176108705977826,1.070123936480939,0.12580968009238108,0.30200233977580343,0.1484683010782358,3.7462657069794476,0.259018664523886,0.21533758545793177,0.36520852896444506,0.9243562959106226,1.9223825076951602,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.5655565678430635,0.5655565678430635,0.7334243460639536,0.8566305867164241,0.9243562959106226,-0.16155054834083413,3.078186020550252,0.259018664523886,0.5267030007716262,0.1484683010782358,0.46730587199900714,-0.11157482962869282,0.19322985148629535,0.7869794546562088,-0.13645324700708894,0.10296255264400622,-0.13645324700708894,-0.39780592754705757,0.46730587199900714,0.7514043268649677,2.3075717767503545,-0.26419124276665046,2.4339675988258307,0.28059656391052684,0.42694183408394704,0.5070546681307051 3193 Active ion transmembrane transporter activity 24 41 2.8712939667936586 0.0040879517067398 Q15043,P55011,P13073,Q7KZN9,Q9UDW1,P41440,Q9Y6M7,O95202,Q9H2J7,P16615,P51798,P47985,Q96ES6,P20020,Q9BXP2,P05023,P12235,Q9HD20,P61421,P00403,P12236,P53007,P08195,P05141 Functions GO Molecular function msigdb_gomf 256,636,136,150,22,654,151,155,289,300,184,448,75,580,475,712,338,87,466,216,217,730,727,361 155,216,712,2449,361,1134,727,752,1790,338,217,136,300,580,2092,1846,2639,1795,888,1617,2864,654,448,3156,184,730,636,466,994,1111,870,256,150,75,475,289,1599,87,22,1980,151 1.8243030426289284,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,0.46730587199900714,0.44720170401297976,-0.21241421080737602,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-0.21241421080737602,0.3443061993948582,-0.11157482962869282,-1.00064563472387,0.5655565678430635,0.8737391734444331,-2.0464349065431278,1.6738619652882785,0.46730587199900714,0.5847653265563068,0.8394016868466264,0.259018664523886,0.19322985148629535,0.36520852896444506,1.392310058750564,1.8465093473865353,2.5291039002629425,0.8394016868466264,1.280324185022697,-0.08691226787820137,2.4176108705977826,3.143317850644801,-0.2904304927178063,1.8465093473865353 3193 Abnormal circulating lipid concentration 28 79 2.8599979352339595 0.0042364376633723 P23786,P22830,Q9Y5L0,P50402,P49748,Q14739,Q9UJS0,Q15800,O43772,Q15125,P06280,O95470,Q8N511,P31751,Q15392,Q9NZJ7,O75381,P07602,Q9BV10,P61916,O75844,P42858,Q9BTV4,O75845,Q15904,Q9NVI7,Q9UBM7,Q9Y4P3 Drugs and Diseases Human Phenotype Ontology msigdb_hp 4,260,397,266,391,147,428,35,162,294,298,171,49,313,63,191,193,72,199,457,81,341,483,224,230,369,370,253 1393,3012,748,162,193,1610,606,81,224,1026,171,1708,298,1318,72,1032,3055,260,4,570,1105,313,3113,2818,1358,3125,581,582,973,1618,341,2866,867,391,266,1853,2911,1324,1542,2616,2409,1800,457,2506,1906,2009,2102,489,759,3163,2691,147,1810,294,63,921,35,230,923,2328,3158,1339,49,2698,877,1681,1683,483,199,1642,1183,369,191,370,2339,428,937,253,397 0.009638014956759703,-1.2782188724392092,0.44720170401297976,1.7905380137060627,1.6375613175769943,-0.11157482962869282,0.6227553904440447,2.4501778760429596,1.4858962903240147,0.23726642403703146,1.744645033106282,-0.16155054834083413,1.2368621349000533,0.0566926794738131,2.5672903217950718,0.23726642403703146,-1.3886547156284181,1.3786129091151909,3.6003046943759847,0.6786968138424812,0.19322985148629535,1.1776036696350574,-1.661294066844009,-0.934824649241834,0.03326476765043723,-1.743326090815665,0.6601866548649779,0.6601866548649779,0.28059656391052684,-0.11157482962869282,1.1013384647454063,-1.00064563472387,0.36520852896444506,0.9739374379111466,1.3648314259575298,-0.23818692761586824,-1.0678476456651755,0.0566926794738131,-0.062462590653624604,-0.7146987125093559,-0.5665281275626076,-0.21241421080737602,0.8566305867164241,-0.6249367779380635,-0.26419124276665046,-0.31690808027229783,-0.37059222129993374,0.8045775073895869,0.44720170401297976,-2.1845722045277824,-0.7760255732552376,1.8684775279957868,-0.21241421080737602,1.2514414118114898,2.6339966056994,0.32323817115644027,2.975065555239934,1.4595591237186676,0.32323817115644027,-0.5092252179873332,-2.1379443966160254,0.0566926794738131,2.7869149799952893,-0.7760255732552376,0.36520852896444506,-0.13645324700708894,-0.13645324700708894,0.8220511190203319,1.6130128562407051,-0.11157482962869282,0.1484683010782358,1.0225160037257737,1.6497305064842487,1.0225160037257737,-0.5092252179873332,0.9243562959106226,0.32323817115644027,1.4059236947909328,0.9739374379111466 3193 Serine hydrolase activity 9 17 2.852342889050489 0.0043398259582669 Q9H3G5,O14773,Q9HB40,Q4J6C6,P67812,P42785,Q16740,O75976,P10619 Functions GO Molecular function msigdb_gomf 38,264,42,235,172,18,185,437,127 264,800,437,127,1539,2358,1711,18,2936,1402,487,172,185,235,625,38,42 1.3648314259575298,0.40652433044515934,0.8907287812193003,2.0857311239846426,-0.062462590653624604,-0.5377405503528547,-0.16155054834083413,3.226034750624375,-1.101981072569348,0.009638014956759703,0.8045775073895869,1.7330122185385242,1.6738619652882785,1.446271558144171,0.6038310370230041,2.926986348323763,2.8899600348937455 3193 Mitochondrial membrane organization 21 47 2.8470671973257966 0.0044124047367122 P52789,Q9NVH1,P45880,Q9NS69,P17152,O95202,O14737,Q5XKP0,Q9H3K2,Q15070,O60313,Q13505,Q6UXV4,Q8IWA4,Q9P0J0,Q9Y512,Q9BUR5,P12235,Q16611,P05141,Q8WWC4 Processes and pathways GO Biological process msigdb_gobp 516,270,15,16,529,155,408,549,302,48,430,51,449,328,201,332,335,338,355,361,502 1313,408,430,1610,1316,2735,155,2140,361,1063,1841,338,529,2894,1657,2543,3155,3000,15,2685,2867,516,51,48,355,660,557,1295,549,449,328,1375,2160,502,2163,335,302,16,270,698,201,1310,1230,1019,332,1703,1272 0.0566926794738131,0.9409967716069575,0.9076007240012801,-0.11157482962869282,0.0566926794738131,-0.8385853324054076,1.8243030426289284,-0.39780592754705757,1.0384916258428032,0.21533758545793177,-0.23818692761586824,1.1013384647454063,0.7334243460639536,-1.034071137875609,-0.13645324700708894,-0.6545664545020534,-2.0464349065431278,-1.2422071670625843,3.285196134499565,-0.7760255732552376,-1.00064563472387,0.7514043268649677,2.746560633651398,2.800152733484291,1.0543605595517835,0.5655565678430635,0.6970721128067479,0.07992440556882748,0.7153141117668748,0.8737391734444331,1.1321439407679112,0.03326476765043723,-0.39780592754705757,0.7869794546562088,-0.39780592754705757,1.1167917984678513,1.2221896821440608,3.2657379732892013,1.3509647782580774,0.5267030007716262,1.6006322940022837,0.07992440556882748,0.12580968009238108,0.259018664523886,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 secondary carrier transporter 10 14 2.8448961095929106 0.0044425910263607 Q15043,Q8TB61,Q9BQT8,Q96ES6,Q9BXP2,Q9UBX3,Q9Y6M7,O75746,O95202,Q9UJS0 Functions Panther Protein class panther_protein_class 256,101,238,75,475,54,151,527,155,428 527,155,636,870,256,954,101,75,238,475,1599,54,428,151 0.7334243460639536,1.8243030426289284,0.5847653265563068,0.36520852896444506,1.392310058750564,0.30200233977580343,2.2988294808347165,2.5291039002629425,1.446271558144171,0.8394016868466264,-0.08691226787820137,2.732890881137026,0.9243562959106226,1.8465093473865353 3193 Organic acid transmembrane transporter activity 17 20 2.8360244359343887 0.0045678950898453 Q15758,P08183,Q9H2J7,Q96NB2,Q9H9B4,P08195,Q02978,P53985,Q9Y619,P33527,Q9BQT8,Q9H2D1,Q9UBX3,P41440,O75746,Q9UJS0,P53007 Functions GO Molecular function msigdb_gomf 899,129,289,677,879,727,870,169,239,888,238,47,54,654,527,428,730 2181,527,129,727,888,654,730,169,870,899,954,677,238,47,289,1599,879,54,428,239 -0.4252722805882104,0.7334243460639536,2.0361169935164405,0.46730587199900714,0.3443061993948582,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.36520852896444506,0.3443061993948582,0.30200233977580343,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,2.732890881137026,0.9243562959106226,1.446271558144171 3193 Metal ion homeostasis 30 79 2.835255886131226 0.0045788993955704 Q8NE01,Q15043,P02786,P51572,P09601,P78417,Q9HC07,Q8IYU8,O95202,Q96A33,Q9BPX6,O75027,P16615,Q8N511,P05067,P30519,Q9Y487,O76024,Q9BXP2,Q9UM00,Q9HD20,P42858,P61421,P62942,Q16611,Q15904,Q8TAD4,Q7L0J3,Q8WWC4,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 128,256,265,141,17,145,146,410,155,284,297,170,300,49,438,69,71,454,475,214,87,341,466,481,355,230,105,108,502,375 1313,1274,1191,514,2264,801,170,1026,3153,454,155,2496,265,3144,2535,712,2449,438,1788,726,2736,802,17,1752,2452,300,1944,864,580,1280,3119,3087,69,3043,2864,341,141,2615,2004,636,466,1623,481,145,994,1717,2551,2689,2273,1043,256,2157,230,355,660,375,108,2831,410,49,2777,128,876,105,502,284,1969,601,297,475,1383,1774,146,87,824,214,71,1019,648 0.0566926794738131,0.07992440556882748,0.12580968009238108,0.7514043268649677,-0.4809780479553145,0.40652433044515934,1.744645033106282,0.23726642403703146,-2.0464349065431278,0.8566305867164241,1.8243030426289284,-0.6249367779380635,1.3648314259575298,-1.9133658565796359,-0.6545664545020534,0.48725623745593405,-0.5955921179420027,0.8907287812193003,-0.21241421080737602,0.46730587199900714,-0.8385853324054076,0.40652433044515934,3.250973747172662,-0.18686982059176915,-0.5955921179420027,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,0.07992440556882748,-1.7020688805675812,-1.5028434769808663,2.589810382359061,-1.3514355919674153,-1.00064563472387,1.1013384647454063,1.9223825076951602,-0.7146987125093559,-0.31690808027229783,0.5847653265563068,0.8394016868466264,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,-0.16155054834083413,-0.6545664545020534,-0.7760255732552376,-0.4809780479553145,0.23726642403703146,1.392310058750564,-0.39780592754705757,1.4595591237186676,1.0543605595517835,0.5655565678430635,1.006432544850282,2.245500235348313,-0.934824649241834,0.9409967716069575,2.7869149799952893,-0.8703399800828923,2.075908277865556,0.36520852896444506,2.2812210779922095,0.7869794546562088,1.2946295225860096,-0.2904304927178063,0.6415400506909451,1.2514414118114898,0.8394016868466264,0.03326476765043723,-0.18686982059176915,1.9009921408923331,2.4176108705977826,0.40652433044515934,1.5376396248754793,2.582335824717171,0.259018664523886,0.5847653265563068 3193 Carboxylic acid transport 25 33 2.8304464928959447 0.0046483085450337 Q15758,P55011,P33527,P28288,Q8TDW0,P41440,O75915,O75746,Q9UJS0,Q9H2J7,Q96NB2,P53985,Q15042,Q9H2D1,Q9UBX3,Q9NZJ7,P07602,P53007,Q9H9B4,O60831,P08195,Q02978,Q9Y619,Q9BQT8,Q7L0J3 Processes and pathways GO Biological process msigdb_gobp 899,636,888,515,929,654,528,527,428,289,677,169,814,47,54,191,72,730,879,478,727,870,239,238,108 2181,1571,478,527,528,1889,2351,72,727,1710,515,888,654,730,169,636,3114,870,814,899,954,108,929,677,238,47,289,1599,879,191,54,428,239 -0.4252722805882104,-0.08691226787820137,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.26419124276665046,-0.5377405503528547,2.5672903217950718,0.46730587199900714,-0.16155054834083413,0.7514043268649677,0.3443061993948582,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.5847653265563068,-1.661294066844009,0.36520852896444506,0.40652433044515934,0.3443061993948582,0.30200233977580343,2.245500235348313,0.32323817115644027,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171 3193 Golgi associated vesicle 11 27 2.8293106604224985 0.0046648393194952 P24390,O43731,P49755,P11717,O95782,Q8N511,P61923,Q9BVK6,P05067,Q15363,Q9Y3B3 Localization GO Cellular component msigdb_gocc 2,36,417,568,485,49,657,444,438,29,30 2635,36,1705,485,438,1990,568,2,990,1069,417,1454,2504,2267,1901,1247,657,1625,1906,29,49,1259,444,1057,1933,30,710 -0.7452104629394918,2.96913415144942,-0.16155054834083413,0.8045775073895869,0.8907287812193003,-0.31690808027229783,0.6786968138424812,3.7462657069794476,0.259018664523886,0.21533758545793177,0.9243562959106226,-0.014190283332690111,-0.6249367779380635,-0.4809780479553145,-0.26419124276665046,0.10296255264400622,0.5655565678430635,-0.11157482962869282,-0.26419124276665046,3.078186020550252,2.7869149799952893,0.10296255264400622,0.8907287812193003,0.23726642403703146,-0.26419124276665046,3.067058131253242,0.5070546681307051 3193 Membrane lipid catabolic process 8 11 2.814364371674604 0.0048873796342865 P06865,P06280,O95470,P17900,P04066,P50897,Q13510,P04062 Processes and pathways GO Biological process msigdb_gobp 293,298,171,234,400,19,116,122 171,122,400,298,293,726,234,19,116,442,707 1.744645033106282,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,1.446271558144171,3.2108682288698214,2.1998773817605315,0.8907287812193003,0.5070546681307051 3193 Disproportionate short stature 13 29 2.8114211259459 0.0049323182100782 P10644,Q7LGA3,Q9UHX1,Q15125,Q9BV10,P16278,Q9UBM7,Q14739,Q8WVQ1,P42345,Q03164,Q15392,Q96HA7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 225,131,37,294,199,11,370,147,311,409,60,63,319 1022,578,2981,1102,225,11,2932,1712,409,1069,60,3163,1631,147,2325,294,63,432,1082,131,842,1214,311,2597,319,575,199,370,37 0.23726642403703146,0.6601866548649779,-1.2065841027857491,0.19322985148629535,1.4858962903240147,3.418959561273887,-1.101981072569348,-0.16155054834083413,0.9409967716069575,0.21533758545793177,2.648478537565285,-2.1845722045277824,-0.11157482962869282,1.8684775279957868,-0.5092252179873332,1.2514414118114898,2.6339966056994,0.9076007240012801,0.21533758545793177,1.985222235335816,0.38594722827302785,0.12580968009238108,1.1925614229636166,-0.6844855875507391,1.162548846164761,0.6786968138424812,1.6130128562407051,1.0225160037257737,2.9330756917337433 3193 Ion transmembrane transport 64 154 2.808138952896768 0.004982872145991 Q15043,P08183,P21796,P27105,P13073,Q9C0H2,Q6P4A7,P45880,P78417,Q9HC07,Q06787,Q9UDW1,P61619,Q7KZN9,O75915,Q9Y6M7,O95202,Q12959,Q9HC21,Q8IYU8,O75964,Q9UJS0,Q13423,Q9H2J7,O43772,Q9BPX6,P56385,Q9NW15,P53985,O75027,P16615,P46934,Q9H2D1,Q70HW3,Q14728,P24539,Q9UBX3,Q9UHG3,P51798,P05067,P47985,Q96ES6,Q9BXP2,O75844,P12235,Q9UM00,Q9HD20,P42858,P00403,P12236,P61421,Q96GC9,P62942,Q16611,O60831,Q8TB61,Q8TAD4,Q9Y619,Q9BQT8,P05141,Q8WWC4,Q9Y277,Q6P4Q7,O43808 Processes and pathways GO Biological process msigdb_gobp 256,129,7,137,136,13,142,15,145,146,532,22,530,150,528,151,155,279,405,410,31,428,161,289,162,297,418,168,169,170,300,416,47,50,305,181,54,59,184,438,448,75,475,81,338,214,87,341,216,217,466,220,481,355,478,101,105,239,238,361,502,247,375,505 2964,1234,2181,748,162,505,553,2264,478,170,2887,1443,1493,2788,527,81,528,2671,31,155,1751,216,712,2449,438,361,2351,1134,1988,826,2736,129,727,752,3092,1790,1709,338,217,136,300,1944,864,580,2092,1846,2639,2956,7,181,1997,137,3119,2894,3043,1795,888,1797,1617,2864,654,341,15,416,1661,448,3131,777,3156,184,730,169,2004,636,1199,418,466,530,1623,481,145,994,1111,1717,870,2463,532,2648,2551,279,161,714,2273,2691,305,1808,2853,256,2157,899,355,142,375,50,150,2831,410,2855,2777,876,105,101,929,502,1736,75,220,1969,677,3098,678,2381,297,238,1427,1054,475,13,1973,1383,47,289,1599,879,146,405,87,1057,904,168,54,22,1696,59,1980,428,824,214,247,2083,1019,239,2443,151 -1.1713430341599453,0.10296255264400622,-0.4252722805882104,0.44720170401297976,1.7905380137060627,0.7692555416447295,0.6970721128067479,-0.4809780479553145,0.8220511190203319,1.744645033106282,-1.034071137875609,-0.014190283332690111,-0.03822288271037234,-0.902417991440706,0.7334243460639536,2.4501778760429596,0.7334243460639536,-0.7760255732552376,3.0502155042807657,1.8243030426289284,-0.18686982059176915,1.5248183397306079,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,0.17094088359372295,-0.31690808027229783,0.38594722827302785,-0.8385853324054076,2.0361169935164405,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,-0.16155054834083413,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,-1.034071137875609,-1.3514355919674153,-0.21241421080737602,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,0.5655565678430635,1.1013384647454063,3.285196134499565,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.42694183408394704,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,-0.5955921179420027,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,0.48725623745593405,-0.4809780479553145,-0.7760255732552376,1.207423100369303,-0.21241421080737602,-0.9675653554604676,1.392310058750564,-0.39780592754705757,0.3443061993948582,1.0543605595517835,1.9117156067218775,1.006432544850282,2.760120300435202,1.8465093473865353,-0.934824649241834,0.9409967716069575,-0.9675653554604676,-0.8703399800828923,0.36520852896444506,2.2812210779922095,2.2988294808347165,0.32323817115644027,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,0.5462030417796385,-1.5417758052175927,0.5462030417796385,-0.5377405503528547,1.2514414118114898,1.446271558144171,0.009638014956759703,0.23726642403703146,0.8394016868466264,3.351325980333631,-0.2904304927178063,0.03326476765043723,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,0.23726642403703146,0.3443061993948582,1.7791593908234755,2.732890881137026,3.143317850644801,-0.13645324700708894,2.6556741514333573,-0.2904304927178063,0.9243562959106226,0.40652433044515934,1.5376396248754793,1.419454626258951,-0.3436274762646461,0.259018664523886,1.446271558144171,-0.5665281275626076,1.8465093473865353 3193 Protein transporter activity 9 13 2.7973691338690387 0.0051520633789488 O60830,Q99595,P49755,Q8NBU5,Q9NS69,O14925,Q9HD20,P61619,Q15388 Functions GO Molecular function msigdb_gomf 0,3,417,628,16,211,87,530,280 211,0,1316,651,417,530,280,628,3,87,16,853,1703 1.5376396248754793,4.042548479567164,0.0566926794738131,0.5655565678430635,0.9243562959106226,0.7334243460639536,1.3088453672804772,0.6038310370230041,3.6753208773984025,2.4176108705977826,3.2657379732892013,0.38594722827302785,-0.13645324700708894 3193 Organelle subcompartment 157 357 2.78970245366032 0.0052756501077986 P24390,Q9P035,Q9BQE5,Q92643,P43307,Q13724,Q14108,P09601,Q15005,P61619,O75915,Q99720,Q8N0U8,O00461,Q15363,Q9Y3B3,Q00765,Q5BJF2,Q15382,P56377,Q15800,O43731,Q8N511,O43865,Q9H2M9,Q96HY6,Q15392,P11717,Q15629,P30519,Q14849,O75844,Q9Y282,Q9HD20,O95197,Q86UE4,Q06136,Q9P2W9,Q8TB61,O60499,Q9NQC3,Q86XL3,Q03518,Q9UKR5,P04062,P51648,O60725,P51572,Q96A57,Q9HC07,Q14739,Q96KC8,Q9UBV2,Q9BRR6,Q16850,Q96G23,Q9BUN8,O95470,P67812,Q86YN1,Q5VUD6,Q8N2H4,Q9Y5M8,Q9BV10,Q8N2K0,P46977,Q9UM00,Q96GC9,P07099,O75845,P48449,Q8TCT9,Q969E2,Q07065,Q15904,Q53GQ0,Q4J6C6,P04439,P04035,Q9Y4P3,Q9Y3A3,P53367,P38435,P53365,Q8IV08,O15260,P50402,O15127,Q12959,Q96RL7,Q9NZ08,Q96A33,Q70UQ0,P57088,P35610,Q96L58,Q15125,P16615,P16435,Q6NUM9,Q9Y5X1,O15269,Q8WVQ1,Q9BT22,P35613,Q8NF37,Q12893,Q2TAA5,Q9UBU6,Q6NUQ4,Q9NPA0,P52292,Q9BUR5,Q92604,Q9NZ01,O95249,Q99442,Q13190,O00443,O00767,Q16706,Q99640,Q9H490,Q9UBM7,O00264,O43852,O95864,Q6UWP7,Q96PC5,Q7Z6M1,Q14534,A1L0T0,P42345,Q9H4A6,Q9H3N1,P49755,Q12981,O95674,Q9BVK6,Q99735,P55735,P06493,P05067,O15126,P10321,O76024,Q96S66,Q8NHH9,Q7Z3C6,O14828,P62942,Q12907,Q86UL3,Q10471,Q10713,Q9Y3A6,Q8N5M9 Localization GO Cellular component msigdb_gocc 2,524,6,519,10,517,14,17,533,530,528,26,27,28,29,30,546,32,548,545,35,36,49,553,577,575,63,568,64,69,74,81,85,87,86,92,99,100,101,103,113,112,111,115,122,130,140,141,143,146,147,148,154,153,158,159,165,171,172,177,178,182,183,199,203,206,214,220,222,224,226,227,228,229,230,236,235,233,245,253,252,248,255,261,262,259,266,274,279,285,287,284,283,282,288,291,294,300,299,301,308,303,311,316,317,318,325,326,331,334,336,333,335,343,347,348,359,354,350,360,362,365,368,370,371,372,374,385,386,394,403,407,409,426,425,417,420,415,444,442,440,439,438,436,455,454,474,472,471,462,481,490,492,489,497,513,511 617,407,1352,371,1098,350,28,2605,360,1099,2635,798,462,771,1572,1394,436,274,259,303,1060,2304,800,36,1705,1492,372,553,1985,103,1396,140,1166,2137,2307,1355,1574,620,81,224,528,454,1317,2734,2311,1888,2447,86,348,2496,2185,171,1194,942,1750,415,374,2036,1787,1497,245,122,233,687,1030,438,439,222,2314,2352,1990,17,3092,455,568,2452,299,300,1066,1447,633,2956,1847,2931,2,1946,3087,865,2815,2843,2718,69,3043,2144,1579,990,288,317,581,255,1896,1897,409,10,2503,206,1069,226,1285,1241,867,1582,417,266,777,1454,756,141,130,1360,333,261,248,2504,2267,2321,2969,440,545,282,2233,3059,2147,1622,1901,1544,656,637,1247,1545,530,713,657,810,2150,481,2461,172,833,2238,994,1625,546,1906,1667,111,1954,99,229,2748,489,1910,497,1365,1407,325,490,279,420,354,1668,2273,2511,517,14,872,2365,838,403,147,674,74,2693,533,1549,814,2240,294,2157,29,548,63,998,693,64,921,35,230,362,2417,158,326,235,236,32,661,1172,178,1336,1211,1514,301,737,334,954,385,283,875,471,394,92,492,1338,112,177,262,817,2831,1732,27,182,203,49,2373,511,1554,318,1003,472,1175,2067,101,1048,1341,587,2594,227,929,1865,1214,1259,311,1638,877,1215,1818,343,1519,519,2332,228,1683,1342,284,143,1640,1050,159,220,1969,575,148,291,1347,386,285,1971,474,359,365,1824,26,442,2599,2381,6,153,2025,2120,316,641,631,165,335,199,1054,3142,444,1307,666,1429,1738,1973,961,577,425,368,426,1008,1183,1974,1092,146,744,87,880,336,113,2292,645,682,707,347,287,524,909,2256,2128,100,1933,1602,370,331,154,853,615,1603,115,3137,214,855,2490,1700,85,986,938,884,252,513,30,2963,253,183,308,3160,710,1833 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3193 Sphingolipid metabolism 7 12 2.7857431334997744 0.0053405172684355 Q06136,P06280,P16278,O95470,Q16880,Q13510,P04062 Processes and pathways KEGG Pathways msigdb_kegg 99,298,11,171,273,116,122 303,1060,619,171,122,298,2891,11,99,116,273,707 1.207423100369303,0.21533758545793177,0.6038310370230041,1.744645033106282,2.153135324237049,1.2368621349000533,-1.034071137875609,3.418959561273887,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.5070546681307051 3193 serine protease 8 18 2.785422515898052 0.0053458014723708 Q9H3G5,Q8N2K0,Q9HB40,Q4J6C6,P67812,P42785,Q16740,P10619 Functions Panther Protein class panther_protein_class 38,203,42,235,172,18,185,127 264,800,565,127,2538,1539,2358,1711,18,2936,172,185,235,203,2959,38,42,2633 1.3648314259575298,0.40652433044515934,0.6786968138424812,2.0857311239846426,-0.6545664545020534,-0.062462590653624604,-0.5377405503528547,-0.16155054834083413,3.226034750624375,-1.101981072569348,1.7330122185385242,1.6738619652882785,1.446271558144171,1.575655220295083,-1.1364774707508174,2.926986348323763,2.8899600348937455,-0.7146987125093559 3193 Clumsiness 9 22 2.781592940613108 0.0054092839749837 O14773,P07602,O75503,O00165,Q13510,P42858,Q9NR77,Q15067,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 264,72,104,45,116,341,61,421,191 45,2086,264,1393,619,514,104,2450,72,2891,2610,1578,341,1328,116,421,1860,2246,424,61,191,1978 2.832792341598909,-0.37059222129993374,1.3648314259575298,0.009638014956759703,0.6038310370230041,0.7514043268649677,2.2812210779922095,-0.5955921179420027,2.5672903217950718,-1.034071137875609,-0.7146987125093559,-0.08691226787820137,1.1013384647454063,0.0566926794738131,2.1998773817605315,0.9243562959106226,-0.23818692761586824,-0.4529950413267082,0.9243562959106226,2.6412527563805264,1.6497305064842487,-0.2904304927178063 3193 Sphingolipid biosynthetic process 8 14 2.7791674939353275 0.0054498416162838 Q06136,O95470,Q16880,Q99805,Q13510,O15269,P04062,Q96G23 Processes and pathways GO Biological process msigdb_gobp 99,171,273,367,116,303,122,159 303,1060,171,122,1847,99,116,273,1295,159,367,707,524,2256 1.207423100369303,0.21533758545793177,1.744645033106282,2.153135324237049,-0.23818692761586824,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.07992440556882748,1.8243030426289284,1.0225160037257737,0.5070546681307051,0.7514043268649677,-0.4529950413267082 3193 Abnormality of femur morphology 21 75 2.773436898307522 0.0055467596528107 Q7LGA3,P16278,P04066,Q14739,Q96A33,Q96L58,Q9UHX1,P06280,P16435,Q8WVQ1,P51798,Q9NZJ7,Q96HA7,O95831,Q9Y487,P07602,Q9BV10,O75844,O00443,Q9Y619,P04062 Drugs and Diseases Human Phenotype Ontology msigdb_hp 131,11,400,147,284,291,37,298,299,311,184,191,319,194,71,72,199,81,350,239,122 1022,350,2605,2086,1393,650,1396,2981,1610,2183,1102,81,1707,194,2036,1708,122,400,2140,298,725,72,669,11,299,2956,1501,1136,3018,3155,2642,1069,184,1140,2770,636,2270,147,2325,1369,2915,432,2277,737,2878,131,2830,1146,842,2697,2974,1214,311,284,600,319,575,291,1347,1425,1426,199,1154,1481,1183,2783,746,1263,191,37,2218,2029,71,1647,239 0.23726642403703146,1.0543605595517835,-0.7146987125093559,-0.37059222129993374,0.009638014956759703,0.5655565678430635,0.009638014956759703,-1.2065841027857491,-0.11157482962869282,-0.4252722805882104,0.19322985148629535,2.4501778760429596,-0.16155054834083413,1.6375613175769943,-0.3436274762646461,-0.16155054834083413,2.153135324237049,0.9575234066599015,-0.39780592754705757,1.2368621349000533,0.46730587199900714,2.5672903217950718,0.5462030417796385,3.418959561273887,1.2368621349000533,-1.1364774707508174,-0.03822288271037234,0.17094088359372295,-1.2782188724392092,-2.0464349065431278,-0.7452104629394918,0.21533758545793177,1.6738619652882785,0.17094088359372295,-0.8703399800828923,0.5847653265563068,-0.4809780479553145,1.8684775279957868,-0.5092252179873332,0.03326476765043723,-1.0678476456651755,0.9076007240012801,-0.4809780479553145,0.46730587199900714,-1.00064563472387,1.985222235335816,-0.934824649241834,0.17094088359372295,0.38594722827302785,-0.7760255732552376,-1.1713430341599453,0.12580968009238108,1.1925614229636166,1.2946295225860096,0.6415400506909451,1.162548846164761,0.6786968138424812,1.2659284528512882,0.0566926794738131,0.009638014956759703,0.009638014956759703,1.6130128562407051,0.17094088359372295,-0.014190283332690111,0.1484683010782358,-0.8703399800828923,0.46730587199900714,0.10296255264400622,1.6497305064842487,2.9330756917337433,-0.4252722805882104,-0.31690808027229783,2.582335824717171,-0.11157482962869282,1.446271558144171 3193 Nucleobase containing compound transmembrane transporter activity 8 13 2.7607579537005877 0.0057667397652256 Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236 Functions GO Molecular function msigdb_gomf 321,101,361,47,338,405,212,217 912,505,361,338,217,654,1171,1112,101,321,212,47,405 0.32323817115644027,0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.1484683010782358,0.19322985148629535,2.2988294808347165,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015 3193 Biliary tract abnormality 7 26 2.755764824620268 0.0058555081561639 P07602,Q14108,P09601,Q14739,P04062,O95202,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 72,14,17,147,122,155,191 619,155,1168,1708,122,72,17,1710,2891,3100,1711,2685,1324,1141,497,2200,14,147,549,1967,1925,1223,191,231,1230,397 0.6038310370230041,1.8243030426289284,0.1484683010782358,-0.16155054834083413,2.153135324237049,2.5672903217950718,3.250973747172662,-0.16155054834083413,-1.034071137875609,-1.581156126510372,-0.16155054834083413,-0.7760255732552376,0.0566926794738131,0.17094088359372295,0.7869794546562088,-0.4252722805882104,3.309160878702859,1.8684775279957868,0.7153141117668748,-0.2904304927178063,-0.26419124276665046,0.12580968009238108,1.6497305064842487,1.4595591237186676,0.12580968009238108,0.9739374379111466 3193 Endopeptidase activity 25 61 2.747043960962974 0.0060135073540692 P28072,Q9BYT8,O14773,Q92643,P60900,Q99797,Q9NZ08,Q14674,P67812,Q16740,P28070,P49721,Q92542,O75844,Q99538,P42892,Q8TCT9,O43847,Q4J6C6,P53634,Q5JRX3,Q9UBR2,Q10713,P40818,P28074 Functions GO Molecular function msigdb_gomf 381,521,264,519,402,411,287,547,172,185,570,65,329,81,346,91,227,605,235,487,625,244,497,622,495 264,800,605,2788,81,826,1539,1654,2402,970,775,3124,570,381,495,2358,2718,1711,622,2742,91,974,2936,2644,65,1663,1664,487,2987,402,172,497,780,547,2588,185,235,625,2109,1815,227,329,519,1767,1967,1866,2021,1262,932,1424,346,411,2564,521,287,1781,244,1438,647,1606,1019 1.3648314259575298,0.40652433044515934,0.6227553904440447,-0.902417991440706,2.4501778760429596,0.38594722827302785,-0.062462590653624604,-0.13645324700708894,-0.5665281275626076,0.28059656391052684,0.42694183408394704,-1.743326090815665,0.6786968138424812,0.9902400838282385,0.7869794546562088,-0.5377405503528547,-0.8071488815311059,-0.16155054834083413,0.6038310370230041,-0.8385853324054076,2.359178009634381,0.28059656391052684,-1.101981072569348,-0.7452104629394918,2.6193923777828645,-0.13645324700708894,-0.13645324700708894,0.8045775073895869,-1.2065841027857491,0.9575234066599015,1.7330122185385242,0.7869794546562088,0.42694183408394704,0.7153141117668748,-0.6844855875507391,1.6738619652882785,1.446271558144171,0.6038310370230041,-0.37059222129993374,-0.21241421080737602,1.472767115384539,1.1321439407679112,0.7514043268649677,-0.18686982059176915,-0.2904304927178063,-0.23818692761586824,-0.31690808027229783,0.10296255264400622,0.32323817115644027,0.009638014956759703,1.0857828718447309,0.9409967716069575,-0.6545664545020534,0.7514043268649677,1.2946295225860096,-0.18686982059176915,1.4329036514563958,0.009638014956759703,0.5847653265563068,-0.08691226787820137,0.259018664523886 3193 Abnormal circulating cholesterol concentration 19 37 2.745815413107896 0.0060360714324863 P50402,Q14739,Q9UJS0,Q15800,Q15125,Q8N511,Q15392,Q9NZJ7,P07602,Q9BV10,P38571,P61916,P42858,Q9BTV4,O75845,Q15904,Q10471,Q9NVI7,Q9UBM7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 266,147,428,35,294,49,63,191,72,199,582,457,341,483,224,230,489,369,370 3012,1610,224,1708,1318,72,3113,581,582,341,2866,266,2911,1800,457,1906,489,759,2691,147,294,63,921,35,230,2328,1339,49,2698,877,483,199,1183,369,191,370,428 -1.2782188724392092,-0.11157482962869282,1.4858962903240147,-0.16155054834083413,0.0566926794738131,2.5672903217950718,-1.661294066844009,0.6601866548649779,0.6601866548649779,1.1013384647454063,-1.00064563472387,1.3648314259575298,-1.0678476456651755,-0.21241421080737602,0.8566305867164241,-0.26419124276665046,0.8045775073895869,0.44720170401297976,-0.7760255732552376,1.8684775279957868,1.2514414118114898,2.6339966056994,0.32323817115644027,2.975065555239934,1.4595591237186676,-0.5092252179873332,0.0566926794738131,2.7869149799952893,-0.7760255732552376,0.36520852896444506,0.8220511190203319,1.6130128562407051,0.1484683010782358,1.0225160037257737,1.6497305064842487,1.0225160037257737,0.9243562959106226 3193 Protein targeting to mitochondrion 19 48 2.735693249699764 0.0062249023482743 O60830,Q99595,P51572,Q9NS69,Q15388,Q99797,O14737,Q8N4H5,O43615,O00165,Q9GZY8,P30536,O95831,Q9P0J0,Q9Y512,O14925,P55786,O95429,Q10713 Processes and pathways GO Biological process msigdb_gobp 0,3,141,16,280,411,408,41,414,45,312,58,194,201,332,211,218,373,497 45,2085,408,211,800,414,0,2788,1316,2735,2889,373,2907,194,651,1063,3129,1399,58,2543,867,2867,141,218,2849,497,280,1917,557,1295,625,1962,41,2832,2779,3,411,312,2253,16,201,1781,2921,1310,512,332,1703,1272 2.832792341598909,-0.37059222129993374,0.9409967716069575,1.5376396248754793,0.40652433044515934,0.9243562959106226,4.042548479567164,-0.902417991440706,0.0566926794738131,-0.8385853324054076,-1.034071137875609,1.006432544850282,-1.0678476456651755,1.6375613175769943,0.5655565678430635,0.21533758545793177,-1.7850748625508288,0.009638014956759703,2.6556741514333573,-0.6545664545020534,0.36520852896444506,-1.00064563472387,1.9223825076951602,1.5248183397306079,-0.9675653554604676,0.7869794546562088,1.3088453672804772,-0.26419124276665046,0.6970721128067479,0.07992440556882748,0.6038310370230041,-0.2904304927178063,2.8899600348937455,-0.934824649241834,-0.8703399800828923,3.6753208773984025,0.9409967716069575,1.1925614229636166,-0.4529950413267082,3.2657379732892013,1.6006322940022837,-0.18686982059176915,-1.0678476456651755,0.07992440556882748,0.7692555416447295,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Organophosphate ester transmembrane transporter activity 8 11 2.734631714594549 0.006245010462003 Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236 Functions GO Molecular function msigdb_gomf 321,101,361,47,338,405,212,217 505,361,338,217,654,1112,101,321,212,47,405 0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.19322985148629535,2.2988294808347165,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015 3193 Nucleotide transmembrane transporter activity 8 11 2.734631714594549 0.006245010462003 Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236 Functions GO Molecular function msigdb_gomf 321,101,361,47,338,405,212,217 505,361,338,217,654,1112,101,321,212,47,405 0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.19322985148629535,2.2988294808347165,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015 3193 Nuclear inner membrane 7 19 2.731640852535322 0.0063019796765089 Q9H1E5,Q5SNT2,P50402,O75844,Q14728,Q14739,Q99720 Localization GO Cellular component msigdb_gocc 98,393,266,81,305,147,26 81,861,2315,1451,1505,266,2823,1404,2009,1460,305,147,1335,393,1146,26,483,98,683 2.4501778760429596,0.36520852896444506,-0.5092252179873332,-0.014190283332690111,-0.03822288271037234,1.3648314259575298,-0.934824649241834,0.009638014956759703,-0.31690808027229783,-0.014190283332690111,1.207423100369303,1.8684775279957868,0.0566926794738131,0.9739374379111466,0.17094088359372295,3.0892345539041384,0.8220511190203319,2.3162732124688055,0.5462030417796385 3193 Cherry red spot of the macula 6 9 2.7309593848385147 0.0063150253618391 P07602,P16278,P17900,Q13510,P10619,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 72,11,234,116,127,191 293,72,726,127,2228,11,234,116,191 1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-0.4529950413267082,3.418959561273887,1.446271558144171,2.1998773817605315,1.6497305064842487 3193 Golgi organization 25 59 2.7177051521907467 0.006573638876248 O15260,Q9Y2L5,P61019,P50570,P62820,Q15363,Q9Y3B3,Q9H4A6,Q8IWJ2,P49755,Q14789,Q9BVK6,P48729,P06493,Q8NCM8,Q9Y6Y8,Q8NHH9,P42858,Q96GC9,Q9UID3,Q13190,Q9P2W9,Q12907,Q9BTU6,Q9Y3A6 Processes and pathways GO Biological process msigdb_gobp 259,795,656,777,531,29,30,426,817,417,674,444,688,439,842,476,472,341,220,615,354,100,490,641,513 1099,1163,1440,1394,259,2304,2137,2307,1574,439,2892,1136,1852,1897,341,688,867,417,777,1622,656,531,2236,833,2100,490,354,674,29,1633,976,1962,817,842,472,2067,1048,1214,1215,1519,220,1347,2599,2381,641,444,426,2122,1008,1183,100,615,1484,2027,1700,795,513,30,476 0.19322985148629535,0.1484683010782358,-0.014190283332690111,0.009638014956759703,1.3786129091151909,-0.5092252179873332,-0.39780592754705757,-0.5092252179873332,-0.08691226787820137,0.8907287812193003,-1.034071137875609,0.17094088359372295,-0.23818692761586824,-0.26419124276665046,1.1013384647454063,0.5267030007716262,0.36520852896444506,0.9243562959106226,0.42694183408394704,-0.11157482962869282,0.5655565678430635,0.7334243460639536,-0.4529950413267082,0.38594722827302785,-0.37059222129993374,0.8045775073895869,1.0543605595517835,0.5462030417796385,3.078186020550252,-0.11157482962869282,0.28059656391052684,-0.2904304927178063,0.40652433044515934,0.38594722827302785,0.8394016868466264,-0.3436274762646461,0.23726642403703146,0.12580968009238108,0.12580968009238108,-0.03822288271037234,1.5248183397306079,0.0566926794738131,-0.6844855875507391,-0.5377405503528547,0.5847653265563068,0.8907287812193003,0.9243562959106226,-0.37059222129993374,0.259018664523886,0.1484683010782358,2.3075717767503545,0.6227553904440447,-0.014190283332690111,-0.31690808027229783,-0.13645324700708894,0.42694183408394704,0.7692555416447295,3.067058131253242,0.8394016868466264 3193 Lipid droplet 12 31 2.712856022821452 0.0066706082324301 Q8NF37,Q9H6V9,P48449,Q9H4M9,Q07065,Q96RL7,Q01105,P51572,Q8NBX0,Q99720,O43760,Q8NBQ5 Localization GO Cellular component msigdb_gocc 318,96,226,452,229,285,488,141,21,26,125,550 2304,125,1985,1131,1750,1787,2576,1988,567,226,2047,1287,141,2969,488,229,814,921,1472,550,21,318,1215,1050,285,26,452,96,880,2441,1833 -0.5092252179873332,2.09550477869399,-0.31690808027229783,0.17094088359372295,-0.18686982059176915,-0.21241421080737602,-0.6844855875507391,-0.31690808027229783,0.6786968138424812,1.4858962903240147,-0.3436274762646461,0.07992440556882748,1.9223825076951602,-1.1713430341599453,0.8045775073895869,1.4595591237186676,0.40652433044515934,0.32323817115644027,-0.014190283332690111,0.7153141117668748,3.148622465340775,1.162548846164761,0.12580968009238108,0.23726642403703146,1.2946295225860096,3.0892345539041384,0.8737391734444331,2.324934091671502,0.36520852896444506,-0.5665281275626076,-0.21241421080737602 3193 Transmembrane transport 91 211 2.712248505089583 0.0066828471423689 O60830,Q99595,P23786,P21796,P52789,P28288,Q9C0H2,P45880,Q9NS69,Q06787,Q9UDW1,P61619,O75915,O75964,Q8WTV0,Q9H2D1,Q70HW3,Q9UBX3,Q9UHG3,Q15629,Q96ES6,O75844,Q9HD20,Q8TB61,Q8TAD4,Q7L0J3,Q03518,Q8IXU6,P04062,Q8NE01,P08183,P27105,P13073,Q6P4A7,P78417,Q9HC07,Q7KZN9,Q9Y6M7,O95202,Q13423,O43772,Q9NW15,P53985,O75027,Q9H2V7,P24539,P51798,O75381,O95831,O14925,Q9UM00,Q9BSK2,P00403,P12236,Q96GC9,Q9Y619,Q9BQT8,Q9Y277,P38435,Q15043,Q12959,Q15388,Q9H2J7,Q9BPX6,P16615,Q14728,P31751,Q99808,P12235,P42858,Q16625,Q16611,Q99442,P05141,Q6P4Q7,Q9HC21,Q8IYU8,Q99797,Q9UJS0,P49755,P56385,P46934,O43615,P05067,P47985,Q9BXP2,P61421,P62942,O60831,Q8WWC4,O43808 Processes and pathways GO Biological process msigdb_gobp 0,3,4,7,516,515,13,15,16,532,22,530,528,31,43,47,50,54,59,64,75,81,87,101,105,108,111,117,122,128,129,137,136,142,145,146,150,151,155,161,162,168,169,170,174,181,184,193,194,211,214,212,216,217,220,239,238,247,255,256,279,280,289,297,300,305,313,321,338,341,342,355,359,361,375,405,410,411,428,417,418,416,414,438,448,475,466,481,478,502,505 912,2604,2964,1234,2181,211,414,748,162,505,553,2264,0,478,170,2887,1443,1493,193,2788,527,81,528,2671,31,1316,155,1751,194,651,216,122,712,2449,438,361,2351,1788,1134,1988,826,1653,2736,129,727,752,3092,1790,3129,863,669,1709,338,217,136,300,1944,864,580,2092,1846,2639,2956,7,4,181,1997,137,3119,515,2894,3043,313,1795,1579,888,1797,1617,255,2864,654,341,15,416,1661,448,3131,417,2867,1853,777,3156,184,516,730,169,2004,636,1199,418,3059,2270,466,530,1623,481,145,994,1111,1717,870,111,2463,2197,532,2648,2551,279,161,714,2273,2691,305,1808,2853,256,2157,280,64,899,922,355,342,2327,557,1112,954,142,375,2973,50,150,108,3007,2831,117,410,2855,2832,2777,128,876,105,101,2594,929,43,502,1736,75,220,1969,677,359,3098,3,678,411,321,2381,297,238,1427,212,1054,475,2289,1429,13,1973,1383,47,289,174,1599,879,2253,146,405,87,1057,904,2808,16,168,54,22,853,1696,59,1980,428,824,1311,214,247,2083,1019,239,2443,151 0.32323817115644027,-0.7146987125093559,-1.1713430341599453,0.10296255264400622,-0.4252722805882104,1.5376396248754793,0.9243562959106226,0.44720170401297976,1.7905380137060627,0.7692555416447295,0.6970721128067479,-0.4809780479553145,4.042548479567164,0.8220511190203319,1.744645033106282,-1.034071137875609,-0.014190283332690111,-0.03822288271037234,1.6375613175769943,-0.902417991440706,0.7334243460639536,2.4501778760429596,0.7334243460639536,-0.7760255732552376,3.0502155042807657,0.0566926794738131,1.8243030426289284,-0.18686982059176915,1.6375613175769943,0.5655565678430635,1.5248183397306079,2.153135324237049,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,-0.21241421080737602,0.17094088359372295,-0.31690808027229783,0.38594722827302785,-0.13645324700708894,-0.8385853324054076,2.0361169935164405,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,-1.7850748625508288,0.36520852896444506,0.5462030417796385,-0.16155054834083413,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,3.6003046943759847,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,0.7514043268649677,-1.034071137875609,-1.3514355919674153,1.1776036696350574,-0.21241421080737602,-0.08691226787820137,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,1.392310058750564,-1.00064563472387,0.5655565678430635,1.1013384647454063,3.285196134499565,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.9243562959106226,-1.00064563472387,-0.23818692761586824,0.42694183408394704,-2.0464349065431278,1.6738619652882785,0.7514043268649677,0.46730587199900714,1.7677180561785404,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,-1.3886547156284181,-0.4809780479553145,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,2.2364631467360248,-0.5955921179420027,-0.4252722805882104,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,0.48725623745593405,-0.4809780479553145,-0.7760255732552376,1.207423100369303,-0.21241421080737602,-0.9675653554604676,1.392310058750564,-0.39780592754705757,1.3088453672804772,2.62670988147732,0.3443061993948582,0.32323817115644027,1.0543605595517835,1.1013384647454063,-0.5092252179873332,0.6970721128067479,0.19322985148629535,0.30200233977580343,1.9117156067218775,1.006432544850282,-1.1713430341599453,2.760120300435202,1.8465093473865353,2.245500235348313,-1.2422071670625843,-0.934824649241834,2.1906198942531567,0.9409967716069575,-0.9675653554604676,-0.934824649241834,-0.8703399800828923,2.075908277865556,0.36520852896444506,2.2812210779922095,2.2988294808347165,-0.6844855875507391,0.32323817115644027,2.871125247428219,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,0.5462030417796385,1.0543605595517835,-1.5417758052175927,3.6753208773984025,0.5462030417796385,0.9409967716069575,1.1473959441543768,-0.5377405503528547,1.2514414118114898,1.446271558144171,0.009638014956759703,1.5376396248754793,0.23726642403703146,0.8394016868466264,-0.4809780479553145,0.009638014956759703,3.351325980333631,-0.2904304927178063,0.03326476765043723,2.813285883739657,1.280324185022697,1.7330122185385242,-0.08691226787820137,0.36520852896444506,-0.4529950413267082,1.9009921408923331,0.9575234066599015,2.4176108705977826,0.23726642403703146,0.3443061993948582,-0.902417991440706,3.2657379732892013,1.7791593908234755,2.732890881137026,3.143317850644801,0.38594722827302785,-0.13645324700708894,2.6556741514333573,-0.2904304927178063,0.9243562959106226,0.40652433044515934,0.07992440556882748,1.5376396248754793,1.419454626258951,-0.3436274762646461,0.259018664523886,1.446271558144171,-0.5665281275626076,1.8465093473865353 3193 Lipid transporter activity 7 16 2.710794517339271 0.006712220850332 P08183,Q14849,P61916,P17900,Q7Z3C6,P30536,Q96GC9 Functions GO Molecular function msigdb_gomf 129,74,457,234,471,58,220 858,129,863,234,1847,515,58,888,1241,457,74,954,471,220,1429,1738 0.36520852896444506,2.0361169935164405,0.36520852896444506,1.446271558144171,-0.23818692761586824,0.7514043268649677,2.6556741514333573,0.3443061993948582,0.10296255264400622,0.8566305867164241,2.536807538431712,0.30200233977580343,0.8394016868466264,1.5248183397306079,0.009638014956759703,-0.16155054834083413 3193 Cellular ion homeostasis 31 87 2.7083461526392947 0.006761945468334 Q15043,Q93050,P02786,P51572,P09601,P78417,P50897,Q9HC07,Q9Y6M7,Q8IYU8,O95202,Q96A33,Q9BPX6,O75027,P16615,Q8N511,Q92544,P05067,Q9Y487,O76024,Q9UM00,Q9HD20,P42858,P61421,P62942,Q16611,Q15904,O75503,Q8TAD4,Q7L0J3,Q8WWC4 Processes and pathways GO Biological process msigdb_gobp 256,138,265,141,17,145,19,146,151,410,155,284,297,170,300,49,315,438,71,454,214,87,341,466,481,355,230,104,105,108,502 1313,1274,2181,514,2264,801,170,104,1026,3153,454,155,2496,686,265,712,2449,438,1788,1134,726,2736,802,17,3092,2714,1752,2452,300,1944,864,580,1280,2892,3119,3087,1136,3043,2864,341,19,1287,141,3156,2615,2004,636,466,1623,481,145,994,1717,1328,2273,1043,256,2157,230,355,660,108,2831,410,49,876,105,502,315,138,284,819,1969,601,297,1383,1774,146,87,1696,1980,824,214,71,1019,2443,151 0.0566926794738131,0.07992440556882748,-0.4252722805882104,0.7514043268649677,-0.4809780479553145,0.40652433044515934,1.744645033106282,2.2812210779922095,0.23726642403703146,-2.0464349065431278,0.8566305867164241,1.8243030426289284,-0.6249367779380635,0.5267030007716262,1.3648314259575298,0.48725623745593405,-0.5955921179420027,0.8907287812193003,-0.21241421080737602,0.17094088359372295,0.46730587199900714,-0.8385853324054076,0.40652433044515934,3.250973747172662,-1.5417758052175927,-0.8071488815311059,-0.18686982059176915,-0.5955921179420027,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,0.07992440556882748,-1.034071137875609,-1.7020688805675812,-1.5028434769808663,0.17094088359372295,-1.3514355919674153,-1.00064563472387,1.1013384647454063,3.2108682288698214,0.07992440556882748,1.9223825076951602,-2.0464349065431278,-0.7146987125093559,-0.31690808027229783,0.5847653265563068,0.8394016868466264,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,-0.16155054834083413,0.0566926794738131,-0.4809780479553145,0.23726642403703146,1.392310058750564,-0.39780592754705757,1.4595591237186676,1.0543605595517835,0.5655565678430635,2.245500235348313,-0.934824649241834,0.9409967716069575,2.7869149799952893,0.36520852896444506,2.2812210779922095,0.7869794546562088,1.1776036696350574,1.9329933181047383,1.2946295225860096,0.40652433044515934,-0.2904304927178063,0.6415400506909451,1.2514414118114898,0.03326476765043723,-0.18686982059176915,1.9009921408923331,2.4176108705977826,-0.13645324700708894,-0.2904304927178063,0.40652433044515934,1.5376396248754793,2.582335824717171,0.259018664523886,-0.5665281275626076,1.8465093473865353 3193 Organic acid transport 30 45 2.7051975823177647 0.0068263773167807 Q15758,P08183,P55011,P23786,P33527,P28288,Q6P4A7,P41440,O75915,O75746,Q9UJS0,Q9H2J7,Q96NB2,O43772,P53985,Q15042,Q9H2D1,Q9UBX3,P31751,P09455,P53007,Q9H9B4,O60831,P08195,Q02978,P11166,Q9Y619,Q9BQT8,Q7L0J3,O43808 Processes and pathways GO Biological process msigdb_gobp 899,129,636,4,888,515,142,654,528,527,428,289,677,162,169,814,47,54,313,567,730,879,478,727,870,863,239,238,108,505 2181,1571,162,505,478,527,528,1750,3084,1889,2351,2186,129,727,567,863,1710,4,515,313,1579,888,654,1853,730,169,636,3114,870,814,899,954,142,108,929,677,238,47,289,1599,879,54,428,2979,239 -0.4252722805882104,-0.08691226787820137,1.7905380137060627,0.7692555416447295,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.18686982059176915,-1.5028434769808663,-0.26419124276665046,-0.5377405503528547,-0.4252722805882104,2.0361169935164405,0.46730587199900714,0.6786968138424812,0.36520852896444506,-0.16155054834083413,3.6003046943759847,0.7514043268649677,1.1776036696350574,-0.08691226787820137,0.3443061993948582,0.5655565678430635,-0.23818692761586824,0.46730587199900714,1.7677180561785404,0.5847653265563068,-1.661294066844009,0.36520852896444506,0.40652433044515934,0.3443061993948582,0.30200233977580343,1.9117156067218775,2.245500235348313,0.32323817115644027,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,2.732890881137026,0.9243562959106226,-1.1713430341599453,1.446271558144171 3193 Secondary active transmembrane transporter activity 11 22 2.693756162932602 0.0070651830945454 Q15043,Q9H2J7,P53985,P05141,Q96ES6,P12235,Q9UBX3,Q9Y6M7,P12236,O95202,P51798 Functions GO Molecular function msigdb_gomf 256,289,169,361,75,338,54,151,217,155,184 155,361,727,338,217,654,3156,184,730,169,636,1111,870,256,899,876,75,475,289,1599,54,151 1.8243030426289284,1.0384916258428032,0.46730587199900714,1.1013384647454063,1.5248183397306079,0.5655565678430635,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.19322985148629535,0.36520852896444506,1.392310058750564,0.3443061993948582,0.36520852896444506,2.5291039002629425,0.8394016868466264,1.280324185022697,-0.08691226787820137,2.732890881137026,1.8465093473865353 3193 MFS transporter superfamily [IPR036259] 6 10 2.691080239583936 0.0071221062611048 Q99808,P53985,Q96ES6,Q9H2V7,Q7L0J3,Q14728 Sequence InterPro Superfamily interpro_homologous_superfamily 321,169,75,174,108,305 863,654,169,305,342,1921,108,75,321,174 0.36520852896444506,0.5655565678430635,1.7677180561785404,1.207423100369303,1.1013384647454063,-0.26419124276665046,2.245500235348313,2.5291039002629425,1.1473959441543768,1.7330122185385242 3193 Sphingolipid metabolism in senescence 6 12 2.6829013464328004 0.0072986517078319 Q06136,P16278,Q13510,O15269,P04062,Q96G23 Processes and pathways WikiPathways msigdb_wp 99,11,116,303,122,159 303,122,1788,725,652,11,728,1136,409,99,116,159 1.207423100369303,2.153135324237049,-0.21241421080737602,0.46730587199900714,0.5655565678430635,3.418959561273887,0.46730587199900714,0.17094088359372295,0.9409967716069575,2.3075717767503545,2.1998773817605315,1.8243030426289284 3193 Nucleotide transport 8 13 2.680605652773781 0.0073489061736742 Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236 Processes and pathways GO Biological process msigdb_gobp 321,101,361,47,338,405,212,217 505,361,338,217,654,835,1112,101,929,321,212,47,405 0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.38594722827302785,0.19322985148629535,2.2988294808347165,0.32323817115644027,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015 3193 primary active transporter 7 22 2.679037188407169 0.0073834193152617 Q9H2J7,O75381,Q9BUN8,Q8N4H5,Q6P4A7,Q9NS69,Q15388 Functions Panther Protein class panther_protein_class 289,193,165,41,142,16,280 1167,193,1316,651,712,2449,2712,1614,300,580,2004,994,280,899,142,41,677,165,289,879,2253,16 0.1484683010782358,1.6375613175769943,0.0566926794738131,0.5655565678430635,0.48725623745593405,-0.5955921179420027,-0.8071488815311059,-0.11157482962869282,1.2368621349000533,0.6601866548649779,-0.31690808027229783,0.259018664523886,1.3088453672804772,0.3443061993948582,1.9117156067218775,2.8899600348937455,0.5462030417796385,1.7905380137060627,1.280324185022697,0.36520852896444506,-0.4529950413267082,3.2657379732892013 3193 Ensheathment of neurons 12 26 2.656491562696032 0.00789584267438 Q92542,O15228,P53634,Q16880,Q7L576,Q15058,Q12959,P31751,O75746,P42345,Q9NR77,P18074 Processes and pathways GO Biological process msigdb_gobp 329,578,487,273,345,366,279,313,527,409,61,569 578,940,527,726,569,313,1502,409,608,487,279,1251,1955,366,1811,273,345,329,2959,1218,1380,61,2131,2080,1093,1019 0.6601866548649779,0.30200233977580343,0.7334243460639536,0.46730587199900714,0.6786968138424812,1.1776036696350574,-0.03822288271037234,0.9409967716069575,0.6227553904440447,0.8045775073895869,1.3088453672804772,0.10296255264400622,-0.2904304927178063,1.0225160037257737,-0.21241421080737602,1.3370121237135937,1.0857828718447309,1.1321439407679112,-1.1364774707508174,0.12580968009238108,0.03326476765043723,2.6412527563805264,-0.37059222129993374,-0.3436274762646461,0.21533758545793177,0.259018664523886 3193 membrane traffic protein 22 63 2.645268464670166 0.0081626127407863 Q9Y2T2,Q9UI14,P20645,Q9H223,Q8TAG9,A6NIH7,P43307,Q9UQ16,P51572,Q13432,Q96RL7,Q9NX40,Q00765,O60313,P78537,Q8N2H4,P11717,Q96FZ7,Q9H4M9,Q12907,O95782,Q96PC5 Functions Panther Protein class panther_protein_class 258,525,633,522,518,9,10,667,141,25,285,286,546,430,572,182,568,588,452,490,485,386 9,1313,1098,1440,1705,430,2137,1133,2764,485,568,633,1893,2455,973,1619,10,2503,867,777,141,2547,3059,2747,572,546,1910,1250,490,25,1172,926,182,518,1735,1966,1681,787,1344,1051,588,386,977,285,2168,666,522,822,847,452,1183,1057,3025,2731,286,2632,1264,2530,525,1484,667,986,258 3.4750650461264545,0.0566926794738131,0.19322985148629535,-0.014190283332690111,-0.16155054834083413,0.9076007240012801,-0.39780592754705757,0.17094088359372295,-0.8703399800828923,0.8045775073895869,0.6786968138424812,0.5847653265563068,-0.26419124276665046,-0.5955921179420027,0.28059656391052684,-0.11157482962869282,3.4750650461264545,-0.6249367779380635,0.36520852896444506,0.42694183408394704,1.9223825076951602,-0.6545664545020534,-1.3886547156284181,-0.8385853324054076,0.6786968138424812,0.7153141117668748,-0.26419124276665046,0.10296255264400622,0.8045775073895869,3.105660523374089,0.1484683010782358,0.32323817115644027,1.6858254775131012,0.7514043268649677,-0.16155054834083413,-0.2904304927178063,-0.13645324700708894,0.42694183408394704,0.0566926794738131,0.23726642403703146,0.6601866548649779,0.9902400838282385,0.28059656391052684,1.2946295225860096,-0.39780592754705757,0.5655565678430635,0.7514043268649677,0.40652433044515934,0.38594722827302785,0.8737391734444331,0.1484683010782358,0.23726642403703146,-1.2782188724392092,-0.8071488815311059,1.2946295225860096,-0.7146987125093559,0.10296255264400622,-0.6249367779380635,0.7514043268649677,-0.014190283332690111,0.5655565678430635,0.28059656391052684,1.392310058750564 3193 Sterol biosynthetic process 11 24 2.6401997477500707 0.0082857175705339 O75845,P48449,Q15800,Q15125,P16435,Q9UBM7,Q14739,Q9UKR5,P04035,Q15392,Q16850 Processes and pathways GO Biological process msigdb_gobp 224,226,35,294,299,370,147,115,245,63,158 224,2311,1787,245,1709,2401,299,581,3000,226,1455,2746,2825,2913,403,147,294,2874,63,921,35,158,370,115 1.4858962903240147,-0.5092252179873332,-0.21241421080737602,1.419454626258951,-0.16155054834083413,-0.5665281275626076,1.2368621349000533,0.6601866548649779,-1.2422071670625843,1.4858962903240147,-0.014190283332690111,-0.8385853324054076,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,1.0225160037257737,2.2182584184461103 3193 Coated vesicle membrane 19 57 2.63209522370493 0.0084860074781025 P24390,P20645,Q9NR31,P02786,Q14108,P61923,Q15363,Q9Y3B3,O43731,P49755,Q8N511,Q15437,P55735,P11717,P10321,Q9Y6Y8,Q13190,O95782,P04439 Localization GO Cellular component msigdb_gocc 2,633,523,265,14,657,29,30,36,417,49,693,440,568,455,476,354,485,233 1313,1883,2635,798,1394,36,1705,2137,1355,1574,2764,2447,1194,942,485,1497,265,233,1990,455,2354,568,1945,633,2,990,1069,867,417,1360,2504,2267,1584,2321,440,657,2747,1625,354,14,1512,783,29,998,693,2328,49,1344,523,1224,1933,2978,2923,2028,30,710,476 0.0566926794738131,-0.26419124276665046,-0.7452104629394918,0.40652433044515934,0.009638014956759703,2.96913415144942,-0.16155054834083413,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.8703399800828923,-0.5955921179420027,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.3648314259575298,1.446271558144171,-0.31690808027229783,0.8566305867164241,-0.5377405503528547,0.6786968138424812,-0.2904304927178063,0.5847653265563068,3.7462657069794476,0.259018664523886,0.21533758545793177,0.36520852896444506,0.9243562959106226,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,-0.08691226787820137,-0.5092252179873332,0.8907287812193003,0.5655565678430635,-0.8385853324054076,-0.11157482962869282,1.0543605595517835,3.309160878702859,-0.03822288271037234,0.42694183408394704,3.078186020550252,0.259018664523886,0.5267030007716262,-0.5092252179873332,2.7869149799952893,0.0566926794738131,0.7514043268649677,0.12580968009238108,-0.26419124276665046,-1.1713430341599453,-1.0678476456651755,-0.31690808027229783,3.067058131253242,0.5070546681307051,0.8394016868466264 3193 Abnormality of head blood vessel 7 21 2.6302975145852803 0.0085310172986543 P07602,P16278,P17900,Q13510,Q9Y4P3,P10619,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 72,11,234,116,253,127,191 1393,885,293,72,726,127,2228,11,234,542,2818,1285,2321,2506,116,1810,2328,2332,191,2339,253 0.009638014956759703,0.3443061993948582,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-0.4529950413267082,3.418959561273887,1.446271558144171,0.7153141117668748,-0.934824649241834,0.07992440556882748,-0.5092252179873332,-0.6249367779380635,2.1998773817605315,-0.21241421080737602,-0.5092252179873332,-0.5092252179873332,1.6497305064842487,-0.5092252179873332,1.4059236947909328 3193 Inner mitochondrial membrane organization 13 21 2.6291258721905697 0.0085604668592649 Q6UXV4,Q9P0J0,Q9Y512,Q9NVH1,Q9H3K2,Q9BUR5,Q16891,O60313,Q13505,Q8WWC4,P17152,O95202,Q5XKP0 Processes and pathways GO Biological process msigdb_gobp 449,201,332,270,302,335,660,430,51,502,529,155,549 430,1610,1316,155,529,3155,51,660,1295,549,449,502,335,302,270,698,201,1019,332,1703,1272 0.9076007240012801,-0.11157482962869282,0.0566926794738131,1.8243030426289284,0.7334243460639536,-2.0464349065431278,2.746560633651398,0.5655565678430635,0.07992440556882748,0.7153141117668748,0.8737391734444331,0.7869794546562088,1.1167917984678513,1.2221896821440608,1.3509647782580774,0.5267030007716262,1.6006322940022837,0.259018664523886,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Mitochondrial nucleotide transporter subfamily 7 9 2.6247517540171037 0.0086712162387123 P05141,Q9H2D1,P12235,Q70HW3,Q9HC21,Q9BSK2,P12236 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 361,47,338,50,405,212,217 505,361,338,217,1112,50,212,47,405 0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.19322985148629535,2.760120300435202,1.5376396248754793,2.813285883739657,0.9575234066599015 3193 Copi dependent golgi to er retrograde traffic 21 52 2.620181080730132 0.0087883087724436 P24390,O15260,P04350,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q12981,Q13509,Q9BVK6,Q9Y678,P68371,P84085,P52732,Q13885,Q9P2W9,Q8N6H7,Q9BUF5 Processes and pathways Reactome Pathways msigdb_reactome 2,259,390,404,657,531,29,30,36,417,420,691,444,710,320,458,596,612,100,500,378 1352,1233,2635,259,2304,36,1574,2312,1535,390,1169,2,972,990,2503,1069,417,596,2504,2267,2547,657,531,320,458,2152,1511,778,420,691,612,2325,29,737,500,1679,1215,1927,2780,2168,378,404,444,2170,1007,1928,961,100,1933,30,857,710 0.03326476765043723,0.10296255264400622,-0.7452104629394918,1.3786129091151909,-0.5092252179873332,2.96913415144942,-0.08691226787820137,-0.5092252179873332,-0.062462590653624604,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.28059656391052684,0.259018664523886,-0.6249367779380635,0.21533758545793177,0.9243562959106226,0.6415400506909451,-0.6249367779380635,-0.4809780479553145,-0.6545664545020534,0.5655565678430635,0.7334243460639536,1.1473959441543768,0.8566305867164241,-0.39780592754705757,-0.03822288271037234,0.42694183408394704,0.9243562959106226,0.5267030007716262,0.6227553904440447,-0.5092252179873332,3.078186020550252,0.46730587199900714,0.7869794546562088,-0.13645324700708894,0.12580968009238108,-0.26419124276665046,-0.8703399800828923,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,-0.39780592754705757,0.259018664523886,-0.26419124276665046,0.30200233977580343,2.3075717767503545,-0.26419124276665046,3.067058131253242,0.38594722827302785,0.5070546681307051 3193 Transport to the golgi and subsequent modification 33 85 2.617551679850799 0.0088563076414511 P24390,Q14203,P04350,O60476,P04066,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q14789,Q13509,Q9BVK6,P55735,P68371,Q12893,P84085,Q9Y6Y8,O95249,Q13885,O15498,Q13190,Q12907,Q9UJW0,Q16706,P53634,Q8N6H7,O75935,Q9UBR2,Q9BUF5,Q96PC5 Processes and pathways Reactome Pathways msigdb_reactome 2,639,390,398,400,404,657,531,29,30,36,417,674,691,444,440,320,325,458,476,348,612,604,354,490,231,362,487,500,240,244,378,386 1532,2635,798,3157,1394,604,1101,1837,36,398,2137,1574,240,2447,348,1194,942,400,390,1169,2,990,2503,2865,1754,1069,867,417,2266,2504,2267,487,2321,2547,440,831,657,531,1624,320,833,458,1327,325,490,2551,354,812,691,813,1041,612,639,1913,674,29,998,362,1172,1116,500,1679,1214,1259,1215,1681,2759,1347,386,2168,378,404,444,961,1183,744,2295,1933,244,231,986,30,710,1162,476 -0.062462590653624604,-0.7452104629394918,0.40652433044515934,-2.1379443966160254,0.009638014956759703,0.6227553904440447,0.19322985148629535,-0.23818692761586824,2.96913415144942,0.9575234066599015,-0.39780592754705757,-0.08691226787820137,1.4329036514563958,-0.5955921179420027,1.070123936480939,0.12580968009238108,0.30200233977580343,0.9575234066599015,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.259018664523886,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.36520852896444506,0.9243562959106226,-0.4809780479553145,-0.6249367779380635,-0.4809780479553145,0.8045775073895869,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,0.38594722827302785,0.8566305867164241,0.0566926794738131,1.1321439407679112,0.8045775073895869,-0.6545664545020534,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.23726642403703146,0.6227553904440447,0.5847653265563068,-0.26419124276665046,0.5462030417796385,3.078186020550252,0.259018664523886,1.0384916258428032,0.1484683010782358,0.19322985148629535,0.7869794546562088,-0.13645324700708894,0.12580968009238108,0.10296255264400622,0.12580968009238108,-0.13645324700708894,-0.8385853324054076,0.0566926794738131,0.9902400838282385,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,0.30200233977580343,0.1484683010782358,0.46730587199900714,-0.4809780479553145,-0.26419124276665046,1.4329036514563958,1.4595591237186676,0.28059656391052684,3.067058131253242,0.5070546681307051,0.17094088359372295,0.8394016868466264 3193 Macromolecule transmembrane transporter activity 6 11 2.613870570709351 0.0089522942783857 O60830,Q99595,P49755,Q9NS69,O14925,Q15388 Functions GO Molecular function msigdb_gomf 0,3,417,16,211,280 211,0,1316,651,417,1171,530,280,3,16,853 1.5376396248754793,4.042548479567164,0.0566926794738131,0.5655565678430635,0.9243562959106226,0.1484683010782358,0.7334243460639536,1.3088453672804772,3.6753208773984025,3.2657379732892013,0.38594722827302785 3193 Copi mediated anterograde transport 24 60 2.6130267731891115 0.0089744271609324 P24390,Q14203,P04350,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q14789,Q13509,Q9BVK6,P68371,Q12893,P84085,O95249,Q13885,O15498,Q13190,Q9UJW0,Q8N6H7,O75935,Q9BUF5 Processes and pathways Reactome Pathways msigdb_reactome 2,639,390,404,657,531,29,30,36,417,674,691,444,320,325,458,348,612,604,354,231,500,240,378 2635,798,3157,604,1101,36,2137,240,348,390,1169,2,990,2503,2865,1754,1069,417,2266,2504,2267,2547,831,657,531,1624,320,833,458,1327,325,2551,354,812,691,813,1041,612,639,1913,674,29,500,1679,1214,1215,2759,1347,2168,378,404,444,961,1183,2295,1933,231,30,710,1162 -0.7452104629394918,0.40652433044515934,-2.1379443966160254,0.6227553904440447,0.19322985148629535,2.96913415144942,-0.39780592754705757,1.4329036514563958,1.070123936480939,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.259018664523886,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.9243562959106226,-0.4809780479553145,-0.6249367779380635,-0.4809780479553145,-0.6545664545020534,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,0.38594722827302785,0.8566305867164241,0.0566926794738131,1.1321439407679112,-0.6545664545020534,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.23726642403703146,0.6227553904440447,0.5847653265563068,-0.26419124276665046,0.5462030417796385,3.078186020550252,0.7869794546562088,-0.13645324700708894,0.12580968009238108,0.12580968009238108,-0.8385853324054076,0.0566926794738131,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,0.30200233977580343,0.1484683010782358,-0.4809780479553145,-0.26419124276665046,1.4595591237186676,3.067058131253242,0.5070546681307051,0.17094088359372295 3193 Corneal opacity 18 52 2.5920524516349306 0.0095405224585425 O75845,O75381,P51648,Q06136,P06280,P16278,P53701,Q9NVI7,P04066,O75844,O43505,Q9UBM7,Q13510,Q16625,Q9Y4P3,P04062,O95202,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 224,193,130,99,298,11,456,369,400,81,275,370,116,342,253,122,155,127 2086,1393,463,275,1024,3040,1941,2981,193,81,224,2035,155,1168,1708,122,400,298,1943,127,11,1615,569,916,3113,2818,973,3120,130,596,456,1361,2409,2506,1906,99,690,2200,116,1810,1915,1858,342,1112,2917,369,719,370,2339,2218,253,1232 -0.37059222129993374,0.009638014956759703,0.8394016868466264,1.3229726085415559,0.23726642403703146,-1.3514355919674153,-0.2904304927178063,-1.2065841027857491,1.6375613175769943,2.4501778760429596,1.4858962903240147,-0.3436274762646461,1.8243030426289284,0.1484683010782358,-0.16155054834083413,2.153135324237049,0.9575234066599015,1.2368621349000533,-0.2904304927178063,2.0857311239846426,3.418959561273887,-0.11157482962869282,0.6786968138424812,0.32323817115644027,-1.661294066844009,-0.934824649241834,0.28059656391052684,-1.7020688805675812,2.015915696016737,0.6415400506909451,0.8566305867164241,0.03326476765043723,-0.5665281275626076,-0.6249367779380635,-0.26419124276665046,2.3075717767503545,0.5267030007716262,-0.4252722805882104,2.1998773817605315,-0.21241421080737602,-0.26419124276665046,-0.23818692761586824,1.1013384647454063,0.19322985148629535,-1.0678476456651755,1.0225160037257737,0.48725623745593405,1.0225160037257737,-0.5092252179873332,-0.4252722805882104,1.4059236947909328,0.12580968009238108 3193 Cis golgi network 6 14 2.582769039454473 0.0098010911098767 P24390,O43731,P49755,Q16706,O00461,O95249 Localization GO Cellular component msigdb_gocc 2,36,417,362,28,348 28,1837,36,348,2,417,994,674,362,1048,1259,1215,2381,513 3.078186020550252,-0.23818692761586824,2.96913415144942,1.070123936480939,3.7462657069794476,0.9243562959106226,0.259018664523886,0.5462030417796385,1.0384916258428032,0.23726642403703146,0.10296255264400622,0.12580968009238108,-0.5377405503528547,0.7692555416447295 3193 Dementia 25 58 2.581247767014119 0.0098443900385201 Q14203,P04350,Q14108,Q06787,Q96RL7,O96008,Q96RR1,P06865,O60313,P05067,Q9NZJ7,Q9Y487,P07602,P61916,O76024,P42858,P00403,Q8WVX9,P21912,Q9UBB4,P17900,O43681,Q13510,P04062,Q9UHD9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 639,390,14,532,285,651,424,293,430,438,191,71,72,457,454,341,216,614,353,494,234,619,116,122,379 1098,858,2636,800,619,430,1193,454,651,216,122,2448,390,438,293,72,1842,2997,2891,234,2315,353,1033,1655,2610,1578,804,1617,2864,341,1505,2744,1141,1361,2969,457,1907,532,2871,116,14,639,1415,2205,1732,2373,614,2425,977,285,424,3098,1824,680,191,494,379,71 0.19322985148629535,0.36520852896444506,-0.7452104629394918,0.40652433044515934,0.6038310370230041,0.9076007240012801,0.12580968009238108,0.8566305867164241,0.5655565678430635,1.5248183397306079,2.153135324237049,-0.5955921179420027,0.9739374379111466,0.8907287812193003,1.2514414118114898,2.5672903217950718,-0.23818692761586824,-1.2422071670625843,-1.034071137875609,1.446271558144171,-0.5092252179873332,1.0543605595517835,0.23726642403703146,-0.13645324700708894,-0.7146987125093559,-0.08691226787820137,0.40652433044515934,-0.11157482962869282,-1.00064563472387,1.1013384647454063,-0.03822288271037234,-0.8385853324054076,0.17094088359372295,0.03326476765043723,-1.1713430341599453,0.8566305867164241,-0.26419124276665046,0.7334243460639536,-1.00064563472387,2.1998773817605315,3.309160878702859,0.5847653265563068,0.009638014956759703,-0.4252722805882104,-0.16155054834083413,-0.5377405503528547,0.6227553904440447,-0.5665281275626076,0.28059656391052684,1.2946295225860096,0.9243562959106226,-1.5417758052175927,-0.21241421080737602,0.5462030417796385,1.6497305064842487,0.8045775073895869,1.006432544850282,2.582335824717171 3193 Exopeptidase activity 13 31 2.573945531763747 0.0100546100639751 Q9H3G5,O14773,P02786,Q9HB40,Q92820,O75844,P42785,Q9UIQ6,Q9UBR2,P55786,Q9NZ08,O75976,P10619 Functions GO Molecular function msigdb_gomf 38,264,265,42,364,81,18,213,244,218,287,437,127 264,81,437,265,1789,127,2715,2815,2358,1450,18,3095,487,218,3044,780,875,1552,364,1342,844,2564,38,1929,42,2215,2943,1776,287,244,213 1.3648314259575298,2.4501778760429596,0.8907287812193003,1.3648314259575298,-0.21241421080737602,2.0857311239846426,-0.8071488815311059,-0.934824649241834,-0.5377405503528547,-0.014190283332690111,3.226034750624375,-1.5417758052175927,0.8045775073895869,1.5248183397306079,-1.3514355919674153,0.42694183408394704,0.36520852896444506,-0.062462590653624604,1.0384916258428032,0.0566926794738131,0.38594722827302785,-0.6545664545020534,2.926986348323763,-0.26419124276665046,2.8899600348937455,-0.4252722805882104,-1.101981072569348,-0.18686982059176915,1.2946295225860096,1.4329036514563958,1.5376396248754793 3193 mitochondria 6 11 2.572686106958009 0.0100912684515477 Q8IWA4,P21796,Q9NVH1,P45880,Q9Y277,Q15388 Localization OpenCell Localization opencell_localization 328,7,270,15,247,280 1316,2735,7,15,2365,280,328,330,523,270,247 0.0566926794738131,-0.8385853324054076,3.5491802513502524,3.285196134499565,-0.5377405503528547,1.3088453672804772,1.1321439407679112,1.1321439407679112,0.7514043268649677,1.3509647782580774,1.419454626258951 3193 Abnormal retinal artery morphology 7 18 2.5705590293615703 0.0101534521377224 P07602,P16278,P17900,Q13510,Q9Y4P3,P10619,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 72,11,234,116,253,127,191 885,293,72,726,127,2228,11,234,542,2818,2321,2506,116,1810,2332,191,2339,253 0.3443061993948582,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-0.4529950413267082,3.418959561273887,1.446271558144171,0.7153141117668748,-0.934824649241834,-0.5092252179873332,-0.6249367779380635,2.1998773817605315,-0.21241421080737602,-0.5092252179873332,1.6497305064842487,-0.5092252179873332,1.4059236947909328 3193 Abnormality of epiphysis morphology 17 56 2.567846460736225 0.0102332470932953 O75381,O95831,Q7LGA3,Q96L58,Q96HA7,P10644,O00443,Q15125,Q9Y619,P16278,P16435,Q9HC07,Q14739,Q8WVQ1,O95202,P51798,P38435 Drugs and Diseases Human Phenotype Ontology msigdb_hp 193,194,131,291,319,225,350,294,239,11,299,146,147,311,155,184,255 1022,350,578,1396,2981,193,506,155,194,1168,225,11,299,2956,1501,1711,255,3155,973,184,1140,2409,2270,3034,1906,2197,778,2200,147,2325,294,921,2277,1172,737,2878,131,2830,956,842,311,2597,319,575,291,1426,1481,1183,146,2783,746,370,2218,1983,2029,239 0.23726642403703146,1.0543605595517835,0.6601866548649779,0.009638014956759703,-1.2065841027857491,1.6375613175769943,0.7692555416447295,1.8243030426289284,1.6375613175769943,0.1484683010782358,1.4858962903240147,3.418959561273887,1.2368621349000533,-1.1364774707508174,-0.03822288271037234,-0.16155054834083413,1.392310058750564,-2.0464349065431278,0.28059656391052684,1.6738619652882785,0.17094088359372295,-0.5665281275626076,-0.4809780479553145,-1.314626024117389,-0.26419124276665046,-0.4252722805882104,0.42694183408394704,-0.4252722805882104,1.8684775279957868,-0.5092252179873332,1.2514414118114898,0.32323817115644027,-0.4809780479553145,0.1484683010782358,0.46730587199900714,-1.00064563472387,1.985222235335816,-0.934824649241834,0.30200233977580343,0.38594722827302785,1.1925614229636166,-0.6844855875507391,1.162548846164761,0.6786968138424812,1.2659284528512882,0.009638014956759703,-0.014190283332690111,0.1484683010782358,1.9009921408923331,-0.8703399800828923,0.46730587199900714,1.0225160037257737,-0.4252722805882104,-0.2904304927178063,-0.31690808027229783,1.446271558144171 3193 Mitochondrial carrier protein [IPR002067] 7 11 2.551703486962007 0.0107197705668304 Q9UJS0,P05141,Q9BQT8,P12235,Q9HC21,P12236,O43808 Sequence InterPro Family interpro_family 428,361,238,338,405,217,505 505,527,361,338,217,730,1112,238,1599,405,428 0.7692555416447295,0.7334243460639536,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.46730587199900714,0.19322985148629535,1.446271558144171,-0.08691226787820137,0.9575234066599015,0.9243562959106226 3193 Glycosphingolipid metabolic process 6 8 2.550400353418876 0.0107599278229031 P06865,P06280,P16278,P17900,Q16880,P04062 Processes and pathways GO Biological process msigdb_gobp 293,298,11,234,273,122 122,298,293,726,11,234,273,367 2.153135324237049,1.2368621349000533,1.2514414118114898,0.46730587199900714,3.418959561273887,1.446271558144171,1.3370121237135937,1.0225160037257737 3193 Rhizomelia 7 14 2.5481254562289264 0.0108303514833951 Q9BV10,Q15125,Q9UBM7,Q14739,Q03164,Q15392,Q96HA7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 199,294,370,147,60,63,319 1022,578,2981,1102,409,1069,60,147,294,63,1214,319,199,370 0.23726642403703146,0.6601866548649779,-1.2065841027857491,0.19322985148629535,0.9409967716069575,0.21533758545793177,2.648478537565285,1.8684775279957868,1.2514414118114898,2.6339966056994,0.12580968009238108,1.162548846164761,1.6130128562407051,1.0225160037257737 3193 Inorganic ion transmembrane transport 40 111 2.5455620637420298 0.0109101967369578 Q15043,P21796,P27105,P13073,P78417,Q9HC07,Q06787,Q9UDW1,Q7KZN9,Q9Y6M7,Q12959,Q8IYU8,O95202,O75964,Q13423,Q9H2J7,Q9BPX6,P56385,P46934,O75027,P16615,P24539,Q9UBX3,Q9UHG3,P51798,P47985,Q96ES6,Q9BXP2,P12235,Q9UM00,Q9HD20,P42858,P00403,P61421,Q96GC9,P62942,Q8TAD4,P05141,Q8WWC4,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 256,7,137,136,145,146,532,22,150,151,279,410,155,31,161,289,297,418,416,170,300,181,54,59,184,448,75,475,338,214,87,341,216,466,220,481,105,361,502,375 1234,2181,748,2264,170,1443,1493,2788,2671,31,155,1751,216,712,2449,361,2351,1134,1988,2736,727,752,1790,1709,338,136,300,1944,864,580,2092,1846,2639,2956,7,181,1997,137,3119,2894,3043,1795,1797,1617,2864,341,416,1661,448,3131,777,3156,184,2004,636,1199,418,466,530,1623,481,145,994,1111,1717,870,2463,532,2648,2551,279,161,2273,2691,2853,256,375,150,2831,410,2855,2777,876,105,502,1736,75,220,1969,3098,678,2381,297,1427,475,1973,1383,289,1599,146,87,904,54,22,1696,59,1980,824,214,1019,151 0.10296255264400622,-0.4252722805882104,0.44720170401297976,-0.4809780479553145,1.744645033106282,-0.014190283332690111,-0.03822288271037234,-0.902417991440706,-0.7760255732552376,3.0502155042807657,1.8243030426289284,-0.18686982059176915,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,-0.5377405503528547,0.17094088359372295,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-0.21241421080737602,-0.16155054834083413,1.1013384647454063,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,-1.034071137875609,-1.3514355919674153,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,1.1013384647454063,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.42694183408394704,-2.0464349065431278,1.6738619652882785,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,-0.5955921179420027,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,-0.4809780479553145,-0.7760255732552376,-0.9675653554604676,1.392310058750564,1.006432544850282,1.8465093473865353,-0.934824649241834,0.9409967716069575,-0.9675653554604676,-0.8703399800828923,0.36520852896444506,2.2812210779922095,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,-1.5417758052175927,0.5462030417796385,-0.5377405503528547,1.2514414118114898,0.009638014956759703,0.8394016868466264,-0.2904304927178063,0.03326476765043723,1.280324185022697,-0.08691226787820137,1.9009921408923331,2.4176108705977826,0.3443061993948582,2.732890881137026,3.143317850644801,-0.13645324700708894,2.6556741514333573,-0.2904304927178063,0.40652433044515934,1.5376396248754793,0.259018664523886,1.8465093473865353 3193 Outer mitochondrial membrane protein complex 12 16 2.5452390023764164 0.0109202965713401 Q6UXV4,Q8IWA4,Q8N4H5,Q9Y512,Q9NVH1,Q9NS69,Q9BUR5,Q16891,Q13505,Q15388,O96008,Q5XKP0 Localization GO Cellular component msigdb_gocc 449,328,41,332,270,16,335,660,51,280,651,549 1610,1316,651,3155,51,280,660,549,449,328,41,335,16,270,698,332 -0.11157482962869282,0.0566926794738131,0.5655565678430635,-2.0464349065431278,2.746560633651398,1.3088453672804772,0.5655565678430635,0.7153141117668748,0.8737391734444331,1.1321439407679112,2.8899600348937455,1.1167917984678513,3.2657379732892013,1.3509647782580774,0.5267030007716262,1.1321439407679112 3193 Protein transmembrane transporter activity 6 10 2.5449993881471373 0.0109277929724513 O60830,Q99595,P49755,Q9NS69,O14925,Q15388 Functions GO Molecular function msigdb_gomf 0,3,417,16,211,280 211,0,1316,651,417,530,280,3,16,853 1.5376396248754793,4.042548479567164,0.0566926794738131,0.5655565678430635,0.9243562959106226,0.7334243460639536,1.3088453672804772,3.6753208773984025,3.2657379732892013,0.38594722827302785 3193 Sterol metabolism 11 26 2.5446607291933367 0.0109383958160034 P35610,O75845,Q15800,Q15125,Q9UBM7,Q14739,Q9UKR5,P04035,Q15392,P04062,Q16850 Processes and pathways Protein Atlas Biological process protein_atlas_biological_process 288,224,35,294,370,147,115,245,63,122,158 858,224,2311,1787,245,122,2401,2607,288,581,2746,457,1952,2825,2913,147,294,2874,63,921,35,158,2328,370,1695,115 0.36520852896444506,1.4858962903240147,-0.5092252179873332,-0.21241421080737602,1.419454626258951,2.153135324237049,-0.5665281275626076,-0.7146987125093559,1.280324185022697,0.6601866548649779,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-1.0678476456651755,1.8684775279957868,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.5092252179873332,1.0225160037257737,-0.13645324700708894,2.2182584184461103 3193 Abnormal biliary tract morphology 9 23 2.537219246032175 0.0111736952014969 Q9Y5L0,Q9UJW0,P07602,Q14108,P09601,Q14739,Q10713,P04062,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 397,231,72,14,17,147,497,122,191 619,1708,122,72,17,1710,2891,3100,1711,2685,1324,1141,497,14,147,549,1967,1925,1223,191,231,1230,397 0.6038310370230041,-0.16155054834083413,2.153135324237049,2.5672903217950718,3.250973747172662,-0.16155054834083413,-1.034071137875609,-1.581156126510372,-0.16155054834083413,-0.7760255732552376,0.0566926794738131,0.17094088359372295,0.7869794546562088,3.309160878702859,1.8684775279957868,0.7153141117668748,-0.2904304927178063,-0.26419124276665046,0.12580968009238108,1.6497305064842487,1.4595591237186676,0.12580968009238108,0.9739374379111466 3193 Avascular necrosis 7 23 2.5345654080303497 0.0112586906295684 Q9Y619,Q14108,O75844,Q9BUR4,P04062,Q9NZ08,P51798 Drugs and Diseases Human Phenotype Ontology msigdb_hp 239,14,81,188,122,287,184 2086,2033,81,2035,1786,1497,1708,122,2400,622,1401,184,2197,14,2878,1145,319,188,1481,746,3122,287,239 -0.37059222129993374,-0.3436274762646461,2.4501778760429596,-0.3436274762646461,-0.21241421080737602,-0.03822288271037234,-0.16155054834083413,2.153135324237049,-0.5665281275626076,0.6038310370230041,0.009638014956759703,1.6738619652882785,-0.4252722805882104,3.309160878702859,-1.00064563472387,0.17094088359372295,1.162548846164761,1.6738619652882785,-0.014190283332690111,0.46730587199900714,-1.7020688805675812,1.2946295225860096,1.446271558144171 3193 Golgi cisterna 12 21 2.532336320642373 0.0113305255464777 Q9H4A6,Q96L58,Q12893,Q10471,Q16706,P51572,O95249,P04439,Q8WVQ1,Q9Y3A3,O00461,Q15363 Localization GO Cellular component msigdb_gocc 426,291,325,489,362,141,348,233,311,252,28,29 28,1099,348,233,3092,141,994,2748,489,497,325,2157,29,362,1048,1259,311,291,426,3137,252 3.078186020550252,0.19322985148629535,1.070123936480939,1.446271558144171,-1.5417758052175927,1.9223825076951602,0.259018664523886,-0.8385853324054076,0.8045775073895869,0.7869794546562088,1.1321439407679112,-0.39780592754705757,3.078186020550252,1.0384916258428032,0.23726642403703146,0.10296255264400622,1.1925614229636166,1.2659284528512882,0.9243562959106226,-1.8273246014917721,1.4059236947909328 3193 Divalent inorganic cation homeostasis 20 54 2.530125601550405 0.0114021701462438 Q15043,Q8NE01,P51572,P78417,Q9HC07,Q8IYU8,O95202,Q96A33,Q9BPX6,P16615,P05067,O76024,Q9UM00,Q9HD20,P42858,P62942,Q16611,Q8TAD4,Q7L0J3,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 256,128,141,145,146,410,155,284,297,300,438,454,214,87,341,481,355,105,108,375 1313,1274,1191,2264,454,155,2496,2449,438,1788,726,2736,802,1752,2452,300,1944,864,580,3119,3087,3043,341,141,2615,1623,481,145,994,1717,2551,2273,1043,256,2157,355,660,375,108,2831,410,128,876,105,502,284,1969,601,297,146,87,824,214,1019 0.0566926794738131,0.07992440556882748,0.12580968009238108,-0.4809780479553145,0.8566305867164241,1.8243030426289284,-0.6249367779380635,-0.5955921179420027,0.8907287812193003,-0.21241421080737602,0.46730587199900714,-0.8385853324054076,0.40652433044515934,-0.18686982059176915,-0.5955921179420027,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-1.7020688805675812,-1.5028434769808663,-1.3514355919674153,1.1013384647454063,1.9223825076951602,-0.7146987125093559,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,-0.16155054834083413,-0.6545664545020534,-0.4809780479553145,0.23726642403703146,1.392310058750564,-0.39780592754705757,1.0543605595517835,0.5655565678430635,1.006432544850282,2.245500235348313,-0.934824649241834,0.9409967716069575,2.075908277865556,0.36520852896444506,2.2812210779922095,0.7869794546562088,1.2946295225860096,-0.2904304927178063,0.6415400506909451,1.2514414118114898,1.9009921408923331,2.4176108705977826,0.40652433044515934,1.5376396248754793,0.259018664523886 3193 Retrograde transport endosome to golgi 11 32 2.5181996598991567 0.0117956434657986 O15498,Q13190,O15260,O60499,O75503,Q4J6C6,Q9BVK6,Q9Y5X3,P53367,O95249,Q9UID3 Processes and pathways GO Biological process msigdb_gobp 604,354,259,103,104,235,444,648,248,348,615 259,604,1164,2222,103,1132,1133,104,348,1897,867,1287,248,1625,354,1548,639,235,1413,926,817,1215,1866,977,444,1056,1565,1264,2178,615,984,648 1.3786129091151909,0.6227553904440447,0.1484683010782358,-0.4529950413267082,2.2812210779922095,0.17094088359372295,0.17094088359372295,2.2812210779922095,1.070123936480939,-0.26419124276665046,0.36520852896444506,0.07992440556882748,1.4059236947909328,-0.11157482962869282,1.0543605595517835,-0.062462590653624604,0.5847653265563068,1.446271558144171,0.009638014956759703,0.32323817115644027,0.40652433044515934,0.12580968009238108,-0.23818692761586824,0.28059656391052684,0.8907287812193003,0.23726642403703146,-0.062462590653624604,0.10296255264400622,-0.39780592754705757,0.6227553904440447,0.28059656391052684,0.5847653265563068 3193 Snare interactions in vesicular transport 8 15 2.5158195284349167 0.0118755975290483 O15498,Q13190,Q9P2W9,Q12981,O60499,O15400,O95721,O95249 Processes and pathways KEGG Pathways msigdb_kegg 604,354,100,420,103,413,399,348 2345,798,413,604,103,1574,348,399,1360,1407,420,354,627,100,855 -0.5377405503528547,0.40652433044515934,0.9243562959106226,0.6227553904440447,2.2812210779922095,-0.08691226787820137,1.070123936480939,0.9575234066599015,0.03326476765043723,0.009638014956759703,0.9243562959106226,1.0543605595517835,0.6038310370230041,2.3075717767503545,0.38594722827302785 3193 Snap receptor activity 8 15 2.5158195284349167 0.0118755975290483 O15498,Q13190,Q9P2W9,Q12981,O60499,O15400,O95721,O95249 Functions GO Molecular function msigdb_gomf 604,354,100,420,103,413,399,348 2345,798,413,604,103,1574,348,399,1360,1407,420,354,627,100,855 -0.5377405503528547,0.40652433044515934,0.9243562959106226,0.6227553904440447,2.2812210779922095,-0.08691226787820137,1.070123936480939,0.9575234066599015,0.03326476765043723,0.009638014956759703,0.9243562959106226,1.0543605595517835,0.6038310370230041,2.3075717767503545,0.38594722827302785 3193 Regulation of cellular ph 8 22 2.515107053477133 0.0118996244700022 Q15904,Q9Y487,Q93050,O75503,Q8N511,Q9HC07,P50897,Q9Y6M7 Processes and pathways GO Biological process msigdb_gobp 230,71,138,104,49,146,19,151 104,686,1134,3092,2892,1136,19,1287,3156,466,1328,230,49,315,138,819,146,1696,1980,71,2443,151 2.2812210779922095,0.5267030007716262,0.17094088359372295,-1.5417758052175927,-1.034071137875609,0.17094088359372295,3.2108682288698214,0.07992440556882748,-2.0464349065431278,0.8394016868466264,0.0566926794738131,1.4595591237186676,2.7869149799952893,1.1776036696350574,1.9329933181047383,0.40652433044515934,1.9009921408923331,-0.13645324700708894,-0.2904304927178063,2.582335824717171,-0.5665281275626076,1.8465093473865353 3193 Regulation of ph 8 22 2.515107053477133 0.0118996244700022 Q15904,Q9Y487,Q93050,O75503,Q8N511,Q9HC07,P50897,Q9Y6M7 Processes and pathways GO Biological process msigdb_gobp 230,71,138,104,49,146,19,151 104,686,1134,3092,2892,1136,19,1287,3156,466,1328,230,49,315,138,819,146,1696,1980,71,2443,151 2.2812210779922095,0.5267030007716262,0.17094088359372295,-1.5417758052175927,-1.034071137875609,0.17094088359372295,3.2108682288698214,0.07992440556882748,-2.0464349065431278,0.8394016868466264,0.0566926794738131,1.4595591237186676,2.7869149799952893,1.1776036696350574,1.9329933181047383,0.40652433044515934,1.9009921408923331,-0.13645324700708894,-0.2904304927178063,2.582335824717171,-0.5665281275626076,1.8465093473865353 3193 Protein transmembrane transport 13 24 2.514419388460101 0.0119228556083517 O60830,Q15629,O75381,Q99595,O95831,P49755,O43615,Q9NS69,O14925,P61619,Q15388,P31751,Q99442 Processes and pathways GO Biological process msigdb_gobp 0,64,193,3,194,417,414,16,211,530,280,313,359 211,414,0,193,1316,194,651,3129,669,313,417,3059,2270,530,280,64,557,3007,2832,359,3,2253,16,853 1.5376396248754793,0.9243562959106226,4.042548479567164,1.6375613175769943,0.0566926794738131,1.6375613175769943,0.5655565678430635,-1.7850748625508288,0.5462030417796385,1.1776036696350574,0.9243562959106226,-1.3886547156284181,-0.4809780479553145,0.7334243460639536,1.3088453672804772,2.62670988147732,0.6970721128067479,-1.2422071670625843,-0.934824649241834,1.0543605595517835,3.6753208773984025,-0.4529950413267082,3.2657379732892013,0.38594722827302785 3193 Synaptic vesicle membrane 9 16 2.513373293290177 0.0119582725792333 O60499,O76024,P20020,Q86Y82,Q15907,Q7L0J3,O43760,O95295,O15126 Localization GO Cellular component msigdb_gocc 103,454,580,627,306,108,125,686,436 1098,436,125,103,454,686,1990,580,1945,1287,1666,783,306,108,627,1378 0.19322985148629535,0.8907287812193003,2.09550477869399,2.2812210779922095,0.8566305867164241,0.5267030007716262,-0.31690808027229783,0.6601866548649779,-0.2904304927178063,0.07992440556882748,-0.13645324700708894,0.42694183408394704,1.207423100369303,2.245500235348313,0.6038310370230041,0.03326476765043723 3193 Dermal atrophy 10 25 2.495531722953656 0.0125768509015145 P10644,Q96L58,P53701,P53634,Q9H1A4,O75844,Q8NCH0,Q9NWM8,P18074,Q15392 Drugs and Diseases Human Phenotype Ontology msigdb_hp 225,291,456,487,504,81,82,406,569,63 2085,2033,81,1786,1708,2140,225,569,916,1105,622,2504,487,456,1667,1367,1811,2157,63,82,291,2431,504,406,719 -0.37059222129993374,-0.3436274762646461,2.4501778760429596,-0.21241421080737602,-0.16155054834083413,-0.39780592754705757,1.4858962903240147,0.6786968138424812,0.32323817115644027,0.19322985148629535,0.6038310370230041,-0.6249367779380635,0.8045775073895869,0.8566305867164241,-0.13645324700708894,0.03326476765043723,-0.21241421080737602,-0.39780592754705757,2.6339966056994,2.4420909128633217,1.2659284528512882,-0.5665281275626076,0.7869794546562088,0.9575234066599015,0.48725623745593405 3193 Disproportionate short limb short stature 11 24 2.488148762987262 0.0128410007359494 P10644,Q7LGA3,Q15125,Q9BV10,Q9UBM7,Q14739,Q8WVQ1,P42345,Q03164,Q15392,Q96HA7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 225,131,294,199,370,147,311,409,60,63,319 1022,578,2981,1102,225,2932,409,1069,60,3163,1631,147,294,63,432,1082,131,842,1214,311,2597,319,199,370 0.23726642403703146,0.6601866548649779,-1.2065841027857491,0.19322985148629535,1.4858962903240147,-1.101981072569348,0.9409967716069575,0.21533758545793177,2.648478537565285,-2.1845722045277824,-0.11157482962869282,1.8684775279957868,1.2514414118114898,2.6339966056994,0.9076007240012801,0.21533758545793177,1.985222235335816,0.38594722827302785,0.12580968009238108,1.1925614229636166,-0.6844855875507391,1.162548846164761,1.6130128562407051,1.0225160037257737 3193 Regulation of autophagy 22 89 2.484104230753577 0.0129877786831591 Q9NZ45,P21796,Q93050,P09601,P42345,O00165,O15269,P30536,Q9NZJ7,Q9Y487,P07602,O75844,P12235,P42858,Q86UE4,Q96DM3,O00443,P05141,P04062,Q9UHD9,P19474,P10619 Processes and pathways GO Biological process msigdb_gobp 134,7,138,17,409,45,303,58,191,71,72,81,338,341,92,357,350,361,122,379,254,127 45,1188,1098,350,1490,858,303,1060,2087,800,1574,1133,81,1317,2907,122,2576,2140,1651,361,826,72,1840,2352,802,17,127,338,254,1399,1846,2639,7,2892,58,1617,2864,1898,409,2742,341,416,2867,1901,466,2824,2049,1290,1717,1907,2869,610,760,2364,838,2588,814,548,1373,92,1418,2373,2698,665,1259,138,787,357,2562,977,3098,1523,577,3010,791,1185,2174,134,191,1781,2178,379,1980,984,1094,512,71,648,1232 2.832792341598909,0.12580968009238108,0.19322985148629535,1.0543605595517835,-0.03822288271037234,0.36520852896444506,1.207423100369303,0.21533758545793177,-0.37059222129993374,0.40652433044515934,-0.08691226787820137,0.17094088359372295,2.4501778760429596,0.0566926794738131,-1.0678476456651755,2.153135324237049,-0.6844855875507391,-0.39780592754705757,-0.13645324700708894,1.0384916258428032,0.38594722827302785,2.5672903217950718,-0.23818692761586824,-0.5377405503528547,0.40652433044515934,3.250973747172662,2.0857311239846426,1.1013384647454063,1.392310058750564,0.009638014956759703,-0.23818692761586824,-0.7452104629394918,3.5491802513502524,-1.034071137875609,2.6556741514333573,-0.11157482962869282,-1.00064563472387,-0.26419124276665046,0.9409967716069575,-0.8385853324054076,1.1013384647454063,0.9243562959106226,-1.00064563472387,-0.26419124276665046,0.8394016868466264,-0.934824649241834,-0.3436274762646461,0.07992440556882748,-0.16155054834083413,-0.26419124276665046,-1.00064563472387,0.6227553904440447,0.44720170401297976,-0.5377405503528547,0.38594722827302785,-0.6844855875507391,0.40652433044515934,0.7153141117668748,0.03326476765043723,2.359178009634381,0.009638014956759703,-0.5377405503528547,-0.7760255732552376,0.5655565678430635,0.10296255264400622,1.9329933181047383,0.42694183408394704,1.0543605595517835,-0.6545664545020534,0.28059656391052684,-1.5417758052175927,-0.03822288271037234,0.6786968138424812,-1.2422071670625843,0.42694183408394704,0.1484683010782358,-0.39780592754705757,1.9748849511122126,1.6497305064842487,-0.18686982059176915,-0.39780592754705757,1.006432544850282,-0.2904304927178063,0.28059656391052684,0.21533758545793177,0.7692555416447295,2.582335824717171,0.5847653265563068,0.12580968009238108 3193 Intrinsic component of golgi membrane 6 9 2.482792748603763 0.0130356905878616 Q8TB61,O15258,Q6ZRP7,O43505,Q9Y282,Q8N2H4 Localization GO Cellular component msigdb_gocc 101,351,295,275,85,182 912,351,275,994,489,295,182,101,85 0.32323817115644027,1.0543605595517835,1.3229726085415559,0.259018664523886,0.8045775073895869,1.2514414118114898,1.6858254775131012,2.2988294808347165,2.4339675988258307 3193 Intrinsic component of plasma membrane 40 76 2.482682959658181 0.0130397085501072 Q15043,P55011,P20645,P02786,P27105,P51572,O60637,P17152,Q99797,Q9UJS0,O96005,Q9H2J7,P53985,Q8WTV0,P16615,Q9Y4G8,O43657,P11279,P05067,P35613,P11717,Q99808,Q92542,P10321,Q8N2K0,P20020,P12235,Q9UIQ6,Q13641,O15111,O15498,Q12907,P05141,Q8TAD4,P04439,Q99805,O00264,A0FGR8,O95864,Q9BTU6 Localization GO Cellular component msigdb_gocc 256,636,633,265,137,141,20,529,411,428,160,289,169,43,300,180,53,309,438,317,568,321,329,455,203,580,338,213,468,463,604,490,361,105,233,367,371,617,374,641 617,371,1236,463,858,604,800,53,20,374,160,1497,265,233,712,2449,438,361,2351,455,863,309,568,338,300,529,1576,580,633,137,865,888,1796,317,1450,654,141,3156,169,2004,636,731,1111,870,835,490,950,468,2853,256,2157,839,899,1338,203,1174,1175,105,929,43,329,411,367,321,2381,641,3192,1973,289,2389,848,2174,213,428,855,180 0.6038310370230041,1.006432544850282,0.10296255264400622,0.8394016868466264,0.36520852896444506,0.6227553904440447,0.40652433044515934,2.732890881137026,3.205778316696798,1.006432544850282,1.8131093029975978,-0.03822288271037234,1.3648314259575298,1.446271558144171,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,0.8566305867164241,0.36520852896444506,1.1925614229636166,0.6786968138424812,1.1013384647454063,1.2368621349000533,0.7334243460639536,-0.08691226787820137,0.6601866548649779,0.5847653265563068,1.9329933181047383,0.36520852896444506,0.3443061993948582,-0.21241421080737602,1.162548846164761,-0.014190283332690111,0.5655565678430635,1.9223825076951602,-2.0464349065431278,1.7677180561785404,-0.31690808027229783,0.5847653265563068,0.46730587199900714,0.19322985148629535,0.36520852896444506,0.38594722827302785,0.8045775073895869,0.30200233977580343,0.8394016868466264,-0.9675653554604676,1.392310058750564,-0.39780592754705757,0.38594722827302785,0.3443061993948582,0.0566926794738131,1.575655220295083,0.1484683010782358,0.1484683010782358,2.2812210779922095,0.32323817115644027,2.871125247428219,1.1321439407679112,0.9409967716069575,1.0225160037257737,1.1473959441543768,-0.5377405503528547,0.5847653265563068,-14.388945867155861,-0.2904304927178063,1.280324185022697,-0.5377405503528547,0.38594722827302785,-0.39780592754705757,1.5376396248754793,0.9243562959106226,0.38594722827302785,1.6977216604154457 3193 Mental deterioration 40 96 2.4788723676325635 0.0131798458563614 Q9BQE5,Q14203,P16278,P04350,O43819,Q14108,P50897,Q06787,Q96RL7,O96008,Q5XKP0,Q96RR1,P21964,P54802,P06865,O95470,O60313,P18074,Q03164,P05067,Q9NZJ7,Q9NPL8,Q9Y487,P07602,P61916,O76024,O75306,P42858,P00403,Q8WVX9,P10644,P21912,Q9UBB4,O75503,P17900,O43681,Q13510,Q10713,P04062,Q9UHD9 Drugs and Diseases Human Phenotype Ontology msigdb_hp 6,639,11,390,514,14,19,532,285,651,549,424,542,166,293,171,430,569,60,438,191,591,71,72,457,454,205,341,216,614,225,353,494,104,234,619,116,497,122,379 1098,858,2636,800,619,514,430,2182,1193,205,104,454,2735,171,651,216,122,2448,390,438,293,72,726,886,2791,1842,2997,225,2891,11,2091,234,569,2315,353,542,1033,1655,2610,1578,804,1617,2864,1451,341,1505,2643,19,2911,2744,1141,166,1361,2969,457,2410,1625,60,1907,2869,532,2775,497,1292,2871,116,14,639,2650,1415,549,2517,2246,2205,1732,2373,614,2425,878,977,285,424,3098,1824,3008,6,2169,591,680,2568,191,494,1978,379,2762,71 0.19322985148629535,0.36520852896444506,-0.7452104629394918,0.40652433044515934,0.6038310370230041,0.7514043268649677,0.9076007240012801,-0.4252722805882104,0.12580968009238108,1.5503857345605445,2.2812210779922095,0.8566305867164241,-0.8385853324054076,1.744645033106282,0.5655565678430635,1.5248183397306079,2.153135324237049,-0.5955921179420027,0.9739374379111466,0.8907287812193003,1.2514414118114898,2.5672903217950718,0.46730587199900714,0.3443061993948582,-0.902417991440706,-0.23818692761586824,-1.2422071670625843,1.4858962903240147,-1.034071137875609,3.418959561273887,-0.37059222129993374,1.446271558144171,0.6786968138424812,-0.5092252179873332,1.0543605595517835,0.7153141117668748,0.23726642403703146,-0.13645324700708894,-0.7146987125093559,-0.08691226787820137,0.40652433044515934,-0.11157482962869282,-1.00064563472387,-0.014190283332690111,1.1013384647454063,-0.03822288271037234,-0.7452104629394918,3.2108682288698214,-1.0678476456651755,-0.8385853324054076,0.17094088359372295,1.7791593908234755,0.03326476765043723,-1.1713430341599453,0.8566305867164241,-0.5665281275626076,-0.11157482962869282,2.648478537565285,-0.26419124276665046,-1.00064563472387,0.7334243460639536,-0.8703399800828923,0.7869794546562088,0.07992440556882748,-1.00064563472387,2.1998773817605315,3.309160878702859,0.5847653265563068,-0.7452104629394918,0.009638014956759703,0.7153141117668748,-0.6249367779380635,-0.4529950413267082,-0.4252722805882104,-0.16155054834083413,-0.5377405503528547,0.6227553904440447,-0.5665281275626076,0.36520852896444506,0.28059656391052684,1.2946295225860096,0.9243562959106226,-1.5417758052175927,-0.21241421080737602,-1.2422071670625843,3.5925647235517952,-0.39780592754705757,0.6601866548649779,0.5462030417796385,-0.6545664545020534,1.6497305064842487,0.8045775073895869,-0.2904304927178063,1.006432544850282,-0.8385853324054076,2.582335824717171 3193 Glycosylation 17 44 2.4763156462630347 0.0132746160566508 Q96L58,Q2TAA5,Q6ZXV5,Q9BV10,Q13724,O75503,Q10471,Q16706,O60476,Q86YN1,O43505,Q9HC07,O60502,Q9Y5P6,P46977,P04062,Q9BT22 Processes and pathways GO Biological process msigdb_gobp 291,326,559,199,517,104,489,362,398,177,275,146,52,445,206,122,316 2605,858,2394,3012,275,398,52,1396,1166,1355,104,2089,122,687,1030,1896,206,713,833,1667,1909,489,517,872,362,326,559,1765,177,587,1214,291,1347,316,199,1973,1222,1183,146,2783,1483,1696,445,3160 -0.7146987125093559,0.36520852896444506,-0.5665281275626076,-1.2782188724392092,1.3229726085415559,0.9575234066599015,2.7397396070190534,0.009638014956759703,0.1484683010782358,0.03326476765043723,2.2812210779922095,-0.37059222129993374,2.153135324237049,0.5267030007716262,0.23726642403703146,-0.26419124276665046,1.5503857345605445,0.48725623745593405,0.38594722827302785,-0.13645324700708894,-0.26419124276665046,0.8045775073895869,0.7514043268649677,0.36520852896444506,1.0384916258428032,1.1321439407679112,0.6970721128067479,-0.18686982059176915,1.7095511162040427,0.6601866548649779,0.12580968009238108,1.2659284528512882,0.0566926794738131,1.1776036696350574,1.6130128562407051,-0.2904304927178063,0.12580968009238108,0.1484683010782358,1.9009921408923331,-0.8703399800828923,-0.014190283332690111,-0.13645324700708894,0.8907287812193003,-2.1379443966160254 3193 Delusions 10 21 2.475319061345856 0.013311719412749 P49770,P21964,Q9BQE5,P04062,P07602,P42858,Q96RL7,Q9NR50,Q9UJS0,Q9NZJ7 Drugs and Diseases Human Phenotype Ontology msigdb_hp 608,542,6,122,72,341,285,349,428,191 2086,619,122,72,886,2891,542,2044,1450,341,608,2614,1251,2154,1302,285,6,349,191,2131,428 -0.37059222129993374,0.6038310370230041,2.153135324237049,2.5672903217950718,0.3443061993948582,-1.034071137875609,0.7153141117668748,-0.3436274762646461,-0.014190283332690111,1.1013384647454063,0.6227553904440447,-0.7146987125093559,0.10296255264400622,-0.39780592754705757,0.07992440556882748,1.2946295225860096,3.5925647235517952,1.070123936480939,1.6497305064842487,-0.37059222129993374,0.9243562959106226 3193 Cellular transition metal ion homeostasis 10 21 2.473643177084297 0.0133743201505822 Q15043,Q15904,Q9Y487,P02786,O75027,Q8TAD4,P09601,Q8N511,P61421,P05067 Processes and pathways GO Biological process msigdb_gobp 256,230,71,265,170,105,17,49,466,438 1313,1274,514,801,170,1026,3153,265,438,17,1280,3043,2864,466,256,230,49,105,1383,1774,71 0.0566926794738131,0.07992440556882748,0.7514043268649677,0.40652433044515934,1.744645033106282,0.23726642403703146,-2.0464349065431278,1.3648314259575298,0.8907287812193003,3.250973747172662,0.07992440556882748,-1.3514355919674153,-1.00064563472387,0.8394016868466264,1.392310058750564,1.4595591237186676,2.7869149799952893,2.2812210779922095,0.03326476765043723,-0.18686982059176915,2.582335824717171 3193 Abnormality of corneal stroma 6 13 2.4725268586840228 0.0134161631944509 O75845,P16278,O43505,Q13510,P04062,P10619 Drugs and Diseases Human Phenotype Ontology msigdb_hp 224,11,275,116,122,127 275,224,122,127,11,1615,569,916,3113,1361,116,342,2218 1.3229726085415559,1.4858962903240147,2.153135324237049,2.0857311239846426,3.418959561273887,-0.11157482962869282,0.6786968138424812,0.32323817115644027,-1.661294066844009,0.03326476765043723,2.1998773817605315,1.1013384647454063,-0.4252722805882104 3193 Calcium signaling pathway 8 17 2.47017248634486 0.0135047918005437 P21796,P05141,P16615,P46020,P45880,P12235,Q9Y277,P12236 Processes and pathways KEGG Pathways msigdb_kegg 7,361,300,486,15,338,247,217 361,1788,338,217,300,1944,864,580,7,15,486,2775,2103,1668,2273,1696,247 1.0384916258428032,-0.21241421080737602,1.1013384647454063,1.5248183397306079,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,3.5491802513502524,3.285196134499565,0.8045775073895869,-0.8703399800828923,-0.37059222129993374,-0.13645324700708894,-0.4809780479553145,-0.13645324700708894,1.419454626258951 3193 Cation transmembrane transport 43 118 2.46937352825038 0.0135349853384882 Q15043,P21796,P27105,P13073,P78417,Q9HC07,Q06787,Q9UDW1,Q7KZN9,Q9Y6M7,Q12959,Q9HC21,O95202,Q8IYU8,O75964,Q13423,Q9H2J7,O43772,Q9BPX6,P56385,Q9NW15,P46934,O75027,P16615,Q70HW3,P24539,P05067,P47985,Q96ES6,Q9BXP2,P12235,Q9UM00,Q9HD20,P42858,P00403,P61421,Q96GC9,P62942,Q8TAD4,Q9Y619,P05141,Q8WWC4,Q6P4Q7 Processes and pathways GO Biological process msigdb_gobp 256,7,137,136,145,146,532,22,150,151,279,405,155,410,31,161,289,162,297,418,168,416,170,300,50,181,438,448,75,475,338,214,87,341,216,466,220,481,105,239,361,502,375 1234,2181,748,162,2264,170,1443,1493,2788,2671,31,155,1751,216,712,2449,438,361,2351,1134,1988,826,2736,727,752,1790,1709,338,136,300,1944,864,580,2092,1846,2639,2956,7,181,1997,137,3119,2894,3043,1795,1797,1617,2864,341,416,1661,448,3131,777,3156,2004,636,1199,418,466,530,1623,481,145,994,1111,1717,2463,532,2648,2551,279,161,2273,2691,2853,256,2157,899,375,50,150,2831,410,2855,2777,876,105,502,1736,75,220,1969,677,3098,678,2381,297,1427,475,1973,1383,289,1599,879,146,405,87,904,168,22,1696,1980,824,214,1019,239,151 0.10296255264400622,-0.4252722805882104,0.44720170401297976,1.7905380137060627,-0.4809780479553145,1.744645033106282,-0.014190283332690111,-0.03822288271037234,-0.902417991440706,-0.7760255732552376,3.0502155042807657,1.8243030426289284,-0.18686982059176915,1.5248183397306079,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,0.17094088359372295,-0.31690808027229783,0.38594722827302785,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-0.21241421080737602,-0.16155054834083413,1.1013384647454063,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,-1.034071137875609,-1.3514355919674153,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,1.1013384647454063,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.42694183408394704,-2.0464349065431278,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,-0.5955921179420027,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,-0.4809780479553145,-0.7760255732552376,-0.9675653554604676,1.392310058750564,-0.39780592754705757,0.3443061993948582,1.006432544850282,2.760120300435202,1.8465093473865353,-0.934824649241834,0.9409967716069575,-0.9675653554604676,-0.8703399800828923,0.36520852896444506,2.2812210779922095,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,0.5462030417796385,-1.5417758052175927,0.5462030417796385,-0.5377405503528547,1.2514414118114898,0.009638014956759703,0.8394016868466264,-0.2904304927178063,0.03326476765043723,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,0.3443061993948582,1.7791593908234755,3.143317850644801,-0.13645324700708894,-0.2904304927178063,0.40652433044515934,1.5376396248754793,0.259018664523886,1.446271558144171,1.8465093473865353 3193 Calmodulin 7 14 2.466220265056498 0.0136547337683892 Q8IYU8,Q9BPX6,Q9BRK5,Q14257,O43852,Q02818,P80303 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 410,297,167,241,372,55,24 372,2682,2322,1665,24,55,241,1412,2114,410,1047,562,297,167 1.006432544850282,-0.7760255732552376,-0.5092252179873332,-0.13645324700708894,3.1219129348274657,2.69120665946763,1.4329036514563958,0.009638014956759703,-0.37059222129993374,0.9409967716069575,0.23726642403703146,0.6970721128067479,1.2514414118114898,1.7791593908234755 3193 Intracellular calcium-sensing protein 7 14 2.466220265056498 0.0136547337683892 Q8IYU8,Q9BPX6,Q9BRK5,Q14257,O43852,Q02818,P80303 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 410,297,167,241,372,55,24 372,2682,2322,1665,24,55,241,1412,2114,410,1047,562,297,167 1.006432544850282,-0.7760255732552376,-0.5092252179873332,-0.13645324700708894,3.1219129348274657,2.69120665946763,1.4329036514563958,0.009638014956759703,-0.37059222129993374,0.9409967716069575,0.23726642403703146,0.6970721128067479,1.2514414118114898,1.7791593908234755 3193 Hexosyltransferase activity 12 32 2.4651567818731626 0.0136953311576779 Q96L58,Q2TAA5,Q6ZXV5,P06865,Q9BV10,Q13126,Q10471,Q16880,P46977,O43505,P04062,Q9BT22 Functions GO Molecular function msigdb_gomf 291,326,559,293,199,73,489,273,206,275,122,316 2605,2394,275,1396,1166,1355,122,687,1030,1318,293,726,1064,1753,1358,945,206,1667,489,73,273,326,559,1765,1593,587,291,316,199,1222,1483,3160 -0.7146987125093559,-0.5665281275626076,1.3229726085415559,0.009638014956759703,0.1484683010782358,0.03326476765043723,2.153135324237049,0.5267030007716262,0.23726642403703146,0.0566926794738131,1.2514414118114898,0.46730587199900714,0.21533758545793177,-0.18686982059176915,0.03326476765043723,0.30200233977580343,1.5503857345605445,-0.13645324700708894,0.8045775073895869,2.5597189348802236,1.3370121237135937,1.1321439407679112,0.6970721128067479,-0.18686982059176915,-0.08691226787820137,0.6601866548649779,1.2659284528512882,1.1776036696350574,1.6130128562407051,0.12580968009238108,-0.014190283332690111,-2.1379443966160254 3193 Regulation of mitochondrion organization 15 45 2.463894063542374 0.0137436725552586 Q9H4A6,P21796,P02786,P05141,Q9NUQ9,Q9H3K2,O00165,Q9Y6C9,P12235,Q96A26,P42858,Q9GZY8,P30536,Q8N2A8,O14737 Processes and pathways GO Biological process msigdb_gobp 426,7,265,361,175,302,45,144,338,83,341,312,58,123,408 45,1098,408,2220,800,430,2223,1708,265,2140,361,1991,338,1399,7,2894,1657,58,3000,341,2685,2867,2364,3127,1962,1375,2160,123,876,2698,2163,83,1596,977,3098,2022,312,302,426,1185,792,175,1781,1310,144 2.832792341598909,0.19322985148629535,0.9409967716069575,-0.4529950413267082,0.40652433044515934,0.9076007240012801,-0.4529950413267082,-0.16155054834083413,1.3648314259575298,-0.39780592754705757,1.0384916258428032,-0.31690808027229783,1.1013384647454063,0.009638014956759703,3.5491802513502524,-1.034071137875609,-0.13645324700708894,2.6556741514333573,-1.2422071670625843,1.1013384647454063,-0.7760255732552376,-1.00064563472387,-0.5377405503528547,-1.743326090815665,-0.2904304927178063,0.03326476765043723,-0.39780592754705757,2.1436487406837603,0.36520852896444506,-0.7760255732552376,-0.39780592754705757,2.4420909128633217,-0.08691226787820137,0.28059656391052684,-1.5417758052175927,-0.31690808027229783,1.1925614229636166,1.2221896821440608,0.9243562959106226,0.1484683010782358,0.42694183408394704,1.7330122185385242,-0.18686982059176915,0.07992440556882748,1.9117156067218775 3193 Protein localization to endoplasmic reticulum 14 34 2.4595999567959104 0.013909195893538 Q15629,P24390,O43731,Q99442,O15258,P51572,Q9NQC3,Q15005,O43681,Q9H2M9,P61619,Q96HY6,Q9Y5M8,P46379 Processes and pathways GO Biological process msigdb_gobp 64,2,36,359,351,141,113,533,619,577,530,575,183,62 1394,351,619,36,1747,2310,2314,2712,1892,2,2683,62,1582,141,3059,2147,1544,2270,637,530,533,814,64,1172,2280,1215,575,359,577,113,2256,853,982,183 0.009638014956759703,1.0543605595517835,0.6038310370230041,2.96913415144942,-0.18686982059176915,-0.5092252179873332,-0.5092252179873332,-0.8071488815311059,-0.26419124276665046,3.7462657069794476,-0.7760255732552376,2.6339966056994,-0.08691226787820137,1.9223825076951602,-1.3886547156284181,-0.39780592754705757,-0.062462590653624604,-0.4809780479553145,0.5847653265563068,0.7334243460639536,0.7334243460639536,0.40652433044515934,2.62670988147732,0.1484683010782358,-0.4809780479553145,0.12580968009238108,0.6786968138424812,1.0543605595517835,0.6786968138424812,2.2364631467360248,-0.4529950413267082,0.38594722827302785,0.28059656391052684,1.6858254775131012 3193 Establishment of protein localization to membrane 21 87 2.4578757479924267 0.0139761519759804 P43307,P27105,O60725,Q9NS69,Q9UPN3,O14737,Q96A33,Q15907,Q15070,Q8N2H4,Q9GZY8,P31751,P46379,Q15629,Q9P0J0,Q9Y512,Q9NPA0,Q9HD20,Q99442,Q15904,Q4J6C6 Processes and pathways GO Biological process msigdb_gobp 10,137,140,16,281,408,284,306,48,182,312,313,62,64,201,332,336,87,359,230,235 2344,1313,408,1394,858,619,1747,140,2533,2310,1316,1750,2449,1063,2314,2712,137,1657,2611,313,2543,2683,973,2097,10,62,2503,1582,1287,1950,2409,3059,1901,2270,637,530,3071,994,1717,1327,2551,2938,781,1549,814,48,64,230,306,235,2652,1295,661,2280,3007,817,182,1554,628,502,284,977,359,312,577,426,1008,1930,87,1057,336,792,16,1691,909,201,853,982,1696,1603,1014,281,1230,2083,332,1703,1272 -0.5377405503528547,0.0566926794738131,0.9409967716069575,0.009638014956759703,0.36520852896444506,0.6038310370230041,-0.18686982059176915,1.9223825076951602,-0.6545664545020534,-0.5092252179873332,0.0566926794738131,-0.18686982059176915,-0.5955921179420027,0.21533758545793177,-0.5092252179873332,-0.8071488815311059,1.9329933181047383,-0.13645324700708894,-0.7146987125093559,1.1776036696350574,-0.6545664545020534,-0.7760255732552376,0.28059656391052684,-0.37059222129993374,3.4750650461264545,2.6339966056994,-0.6249367779380635,-0.08691226787820137,0.07992440556882748,-0.2904304927178063,-0.5665281275626076,-1.3886547156284181,-0.26419124276665046,-0.4809780479553145,0.5847653265563068,0.7334243460639536,-1.426290709801661,0.259018664523886,-0.16155054834083413,0.0566926794738131,-0.6545664545020534,-1.101981072569348,0.42694183408394704,-0.062462590653624604,0.40652433044515934,2.800152733484291,2.62670988147732,1.4595591237186676,1.207423100369303,1.446271558144171,-0.7452104629394918,0.07992440556882748,0.5655565678430635,-0.4809780479553145,-1.2422071670625843,0.40652433044515934,1.6858254775131012,-0.062462590653624604,0.6038310370230041,0.7869794546562088,1.2946295225860096,0.28059656391052684,1.0543605595517835,1.1925614229636166,0.6786968138424812,0.9243562959106226,0.259018664523886,-0.26419124276665046,2.4176108705977826,0.23726642403703146,1.1167917984678513,0.42694183408394704,3.2657379732892013,-0.13645324700708894,0.3443061993948582,1.6006322940022837,0.38594722827302785,0.28059656391052684,-0.13645324700708894,-0.08691226787820137,0.259018664523886,1.3088453672804772,0.12580968009238108,-0.3436274762646461,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Rho gtpases activate iqgaps 7 12 2.453817788377873 0.0141348583821498 Q13885,P68371,Q13576,P04350,Q86VI3,Q9BVA1,Q9BUF5 Processes and pathways Reactome Pathways msigdb_reactome 612,320,135,390,433,404,378 390,2189,1502,1323,1622,320,691,135,612,433,378,404 0.9739374379111466,-0.4252722805882104,-0.03822288271037234,0.0566926794738131,-0.11157482962869282,1.1473959441543768,0.5267030007716262,1.9435485068003742,0.6227553904440447,0.9076007240012801,1.006432544850282,0.9575234066599015 3193 Hormone metabolic process 11 32 2.453444562893095 0.0141495347483324 Q53GQ0,Q8TAD4,Q9HB40,O95470,P16435,Q6NUM9,Q14849,O75844,Q9UBR2,P30536,P42892 Processes and pathways GO Biological process msigdb_gobp 236,105,42,171,299,301,74,81,244,58,91 1165,81,2397,171,712,567,1654,2842,299,58,91,3151,1324,2197,74,1463,236,301,1861,501,550,105,1341,2975,1969,3008,42,1092,370,244,2762,884 0.1484683010782358,2.4501778760429596,-0.5665281275626076,1.744645033106282,0.48725623745593405,0.6786968138424812,-0.13645324700708894,-0.9675653554604676,1.2368621349000533,2.6556741514333573,2.359178009634381,-2.0015302332107483,0.0566926794738131,-0.4252722805882104,2.536807538431712,-0.014190283332690111,1.446271558144171,1.2221896821440608,-0.23818692761586824,0.7869794546562088,0.7153141117668748,2.2812210779922095,0.0566926794738131,-1.1713430341599453,-0.2904304927178063,-1.2422071670625843,2.8899600348937455,0.21533758545793177,1.0225160037257737,1.4329036514563958,-0.8385853324054076,0.36520852896444506 3193 Leukocyte mediated cytotoxicity 6 14 2.4463730036730285 0.014430162431932 P68371,O15400,Q9NUQ9,P04439,P07437,P11279 Processes and pathways GO Biological process msigdb_gobp 320,413,175,233,401,309 413,1705,2575,1497,233,401,309,972,1360,487,320,930,175,1389 0.9243562959106226,-0.16155054834083413,-0.6844855875507391,-0.03822288271037234,1.446271558144171,0.9575234066599015,1.1925614229636166,0.28059656391052684,0.03326476765043723,0.8045775073895869,1.1473959441543768,0.32323817115644027,1.7330122185385242,0.03326476765043723 3193 Er to golgi anterograde transport 30 82 2.444582746062736 0.014501981003465 P24390,Q14203,P04350,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q14789,Q13509,Q9BVK6,P55735,P68371,Q12893,P84085,Q9Y6Y8,O95249,Q13885,O15498,Q13190,Q12907,Q9UJW0,P53634,Q8N6H7,O75935,Q9UBR2,Q9BUF5,Q96PC5 Processes and pathways Reactome Pathways msigdb_reactome 2,639,390,404,657,531,29,30,36,417,674,691,444,440,320,325,458,476,348,612,604,354,490,231,487,500,240,244,378,386 1532,2635,798,3157,1394,604,1101,1837,36,2137,1574,240,2447,348,1194,942,390,1169,2,990,2503,2865,1754,1069,867,417,2266,2504,2267,487,2321,2547,440,831,657,531,1624,320,833,458,1327,325,490,2551,354,812,691,813,1041,612,639,1913,674,29,998,1172,1116,500,1679,1214,1259,1215,1681,2759,1347,386,2168,378,404,444,961,1183,744,2295,1933,244,231,986,30,710,1162,476 -0.062462590653624604,-0.7452104629394918,0.40652433044515934,-2.1379443966160254,0.009638014956759703,0.6227553904440447,0.19322985148629535,-0.23818692761586824,2.96913415144942,-0.39780592754705757,-0.08691226787820137,1.4329036514563958,-0.5955921179420027,1.070123936480939,0.12580968009238108,0.30200233977580343,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.259018664523886,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.36520852896444506,0.9243562959106226,-0.4809780479553145,-0.6249367779380635,-0.4809780479553145,0.8045775073895869,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,0.38594722827302785,0.8566305867164241,0.0566926794738131,1.1321439407679112,0.8045775073895869,-0.6545664545020534,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.23726642403703146,0.6227553904440447,0.5847653265563068,-0.26419124276665046,0.5462030417796385,3.078186020550252,0.259018664523886,0.1484683010782358,0.19322985148629535,0.7869794546562088,-0.13645324700708894,0.12580968009238108,0.10296255264400622,0.12580968009238108,-0.13645324700708894,-0.8385853324054076,0.0566926794738131,0.9902400838282385,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,0.30200233977580343,0.1484683010782358,0.46730587199900714,-0.4809780479553145,-0.26419124276665046,1.4329036514563958,1.4595591237186676,0.28059656391052684,3.067058131253242,0.5070546681307051,0.17094088359372295,0.8394016868466264 3193 Calcium-binding protein 7 16 2.4381493562038727 0.0147626730926939 Q9BPX6,Q9BRK5,P43307,Q14257,O43852,Q02818,P80303 Drugs and Diseases Pharos Drug Target Ontology pharos_dto 297,167,10,241,372,55,24 372,3087,2682,10,2322,1665,24,55,241,1412,2114,410,1047,562,297,167 1.006432544850282,-1.5028434769808663,-0.7760255732552376,3.4750650461264545,-0.5092252179873332,-0.13645324700708894,3.1219129348274657,2.69120665946763,1.4329036514563958,0.009638014956759703,-0.37059222129993374,0.9409967716069575,0.23726642403703146,0.6970721128067479,1.2514414118114898,1.7791593908234755 3193 Monooxygenase activity 7 9 2.4366998010334324 0.0148219785779044 Q9BU89,Q15800,P30519,P09601,Q14534,Q6UW02,Q16850 Functions GO Molecular function msigdb_gomf 520,35,69,17,403,189,158 620,17,69,1902,403,35,158,189,520 0.6038310370230041,3.250973747172662,2.589810382359061,-0.26419124276665046,0.9575234066599015,2.975065555239934,1.8243030426289284,1.661830514045592,0.7514043268649677 3193 Exocytic vesicle 21 41 2.4351576102783548 0.0148853044558243 Q9UI14,P61026,Q96A57,P50897,O15400,Q15019,Q15907,Q9BVK6,Q9BT78,P11279,Q9GZY8,P05067,O15126,Q92542,O76024,P20020,P61421,O60499,Q7L0J3,Q86Y82,O43760 Localization GO Cellular component msigdb_gocc 525,637,143,19,413,692,306,444,443,309,312,438,436,329,454,580,466,103,108,627,125 1098,1571,436,413,125,103,454,686,438,1990,309,580,1945,3119,19,1287,1454,3156,1901,1666,637,466,1407,2689,3077,692,783,2157,306,1143,108,627,329,1378,1767,143,443,444,312,525,986 0.19322985148629535,-0.08691226787820137,0.8907287812193003,0.9243562959106226,2.09550477869399,2.2812210779922095,0.8566305867164241,0.5267030007716262,0.8907287812193003,-0.31690808027229783,1.1925614229636166,0.6601866548649779,-0.2904304927178063,-1.7020688805675812,3.2108682288698214,0.07992440556882748,-0.014190283332690111,-2.0464349065431278,-0.26419124276665046,-0.13645324700708894,0.5847653265563068,0.8394016868466264,0.009638014956759703,-0.7760255732552376,-1.4643510697454634,0.5267030007716262,0.42694183408394704,-0.39780592754705757,1.207423100369303,0.17094088359372295,2.245500235348313,0.6038310370230041,1.1321439407679112,0.03326476765043723,-0.18686982059176915,1.9117156067218775,0.8907287812193003,0.8907287812193003,1.1925614229636166,0.7514043268649677,0.28059656391052684 3193 Inorganic anion transmembrane transporter activity 8 21 2.432388461491644 0.0149996105492293 P21796,Q9NW15,Q9C0H2,P45880,Q9Y277,Q9UBX3,Q9Y6M7,P51798 Functions GO Molecular function msigdb_gomf 7,168,13,15,247,54,151,184 2964,619,3092,7,888,15,3156,184,636,870,256,1921,929,474,475,13,168,54,247,2443,151 -1.1713430341599453,0.6038310370230041,-1.5417758052175927,3.5491802513502524,0.3443061993948582,3.285196134499565,-2.0464349065431278,1.6738619652882785,0.5847653265563068,0.36520852896444506,1.392310058750564,-0.26419124276665046,0.32323817115644027,0.8394016868466264,0.8394016868466264,3.351325980333631,1.7791593908234755,2.732890881137026,1.419454626258951,-0.5665281275626076,1.8465093473865353 3193 Recruitment of numa to mitotic centrosomes 24 36 2.431817988238312 0.0150232546099517 Q14203,P04350,P07437,Q9BVA1,P30153,O94927,Q13409,Q13561,Q9BSJ2,Q13509,Q96RT7,Q96CS2,P06493,P68371,Q15154,Q9H6D7,P43034,P61163,Q96CW5,Q13885,O75935,O95684,Q7Z4H7,Q9BUF5 Processes and pathways Reactome Pathways msigdb_reactome 639,390,401,404,917,290,812,813,959,691,576,574,439,320,585,197,583,831,741,612,240,118,376,378 240,290,118,390,439,401,1063,917,1658,583,1107,831,2410,1623,1624,320,812,691,813,612,2274,639,1913,2776,585,1916,976,376,574,741,576,2381,959,378,404,197 1.4329036514563958,1.2659284528512882,2.1813172981447764,0.9739374379111466,0.8907287812193003,0.9575234066599015,0.21533758545793177,0.32323817115644027,-0.13645324700708894,0.6601866548649779,0.19322985148629535,0.38594722827302785,-0.5665281275626076,-0.11157482962869282,-0.11157482962869282,1.1473959441543768,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.6227553904440447,-0.4809780479553145,0.5847653265563068,-0.26419124276665046,-0.8703399800828923,0.6601866548649779,-0.26419124276665046,0.28059656391052684,1.006432544850282,0.6786968138424812,0.46730587199900714,0.6786968138424812,-0.5377405503528547,0.30200233977580343,1.006432544850282,0.9575234066599015,1.6253223144467295 3193 Cellular monovalent inorganic cation homeostasis 8 26 2.423063649278181 0.0153902299100199 Q15904,Q9Y487,Q93050,O75503,Q8N511,Q9HC07,P50897,Q9Y6M7 Processes and pathways GO Biological process msigdb_gobp 230,71,138,104,49,146,19,151 104,686,712,2449,1134,3092,2892,1136,19,1287,3156,2004,636,466,1328,230,49,315,138,819,146,1696,1980,71,2443,151 2.2812210779922095,0.5267030007716262,0.48725623745593405,-0.5955921179420027,0.17094088359372295,-1.5417758052175927,-1.034071137875609,0.17094088359372295,3.2108682288698214,0.07992440556882748,-2.0464349065431278,-0.31690808027229783,0.5847653265563068,0.8394016868466264,0.0566926794738131,1.4595591237186676,2.7869149799952893,1.1776036696350574,1.9329933181047383,0.40652433044515934,1.9009921408923331,-0.13645324700708894,-0.2904304927178063,2.582335824717171,-0.5665281275626076,1.8465093473865353 3193 Mitochondrial protein import 18 35 2.4228241161050983 0.0154003809082319 O60830,Q99595,P21796,Q8N4H5,O43615,Q9Y512,Q5JRX3,Q9NS69,P12235,Q13505,Q3ZCQ8,O14925,Q10713,Q15388,P12236,O75746,O96008,Q9UJS0 Processes and pathways Reactome Pathways msigdb_reactome 0,3,7,41,414,332,625,16,338,51,557,211,497,280,217,527,651,428 211,414,0,3066,1610,2788,527,1316,651,1134,752,3129,338,217,7,1997,3155,1507,497,51,280,557,625,41,2832,3,3009,2253,16,698,428,1230,332,1703,1272 1.5376396248754793,0.9243562959106226,4.042548479567164,-1.426290709801661,-0.11157482962869282,-0.902417991440706,0.7334243460639536,0.0566926794738131,0.5655565678430635,0.17094088359372295,0.44720170401297976,-1.7850748625508288,1.1013384647454063,1.5248183397306079,3.5491802513502524,-0.31690808027229783,-2.0464349065431278,-0.03822288271037234,0.7869794546562088,2.746560633651398,1.3088453672804772,0.6970721128067479,0.6038310370230041,2.8899600348937455,-0.934824649241834,3.6753208773984025,-1.2422071670625843,-0.4529950413267082,3.2657379732892013,0.5267030007716262,0.9243562959106226,0.12580968009238108,1.1321439407679112,-0.13645324700708894,0.10296255264400622 3193 Sphingolipid pathway 6 9 2.420755297158377 0.0154882993854339 Q06136,O95470,Q16880,Q13510,P04062,Q96G23 Processes and pathways WikiPathways msigdb_wp 99,171,273,116,122,159 303,1060,171,122,3096,99,116,273,159 1.207423100369303,0.21533758545793177,1.744645033106282,2.153135324237049,-1.5417758052175927,2.3075717767503545,2.1998773817605315,1.3370121237135937,1.8243030426289284 3193