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c034469 verified
term overlap setsize score pval
Rna binding 731 1221 inf 0.0
Cadherin binding 152 253 5.595972185076255 2.1938887577998517e-08
Mrna binding 146 211 5.444470880168689 5.1959602901287316e-08
Dna binding transcription factor activity 71 105 -5.2466781538963385 1.548660909631349e-07
Structural molecule activity 165 270 5.147044573049952 2.646224657176788e-07
Cell adhesion molecule binding 164 299 5.029752495344061 4.911133748564112e-07
Structural constituent of ribosome 93 139 4.823889739256416 1.4078526482386169e-06
Translation regulator activity 64 89 4.673250759000808 2.964694292728609e-06
Dna binding transcription activator activity 36 50 -4.644232643215585 3.4134275690433924e-06
Translation factor activity rna binding 41 60 4.572301245965103 4.823967248324124e-06
Translation regulator activity nucleic acid binding 51 71 4.5145484171964645 6.345182524514215e-06
Ligase activity forming carbon oxygen bonds 25 39 4.472618056600996 7.726771642513341e-06
Dna binding transcription repressor activity 30 39 -4.366086783631985 1.2649223963379086e-05
Apolipoprotein receptor binding 0 1 4.365344298113535 1.269226834077486e-05
Arginine binding 0 1 4.361968829091556 1.288972374391406e-05
Primary amine oxidase activity 1 1 -4.340546782317548 1.4212860395712568e-05
Peptidoglycan binding 0 1 4.339995933536729 1.4248535273875262e-05
Cd4 receptor binding 1 1 -4.323558191960662 1.535326162382944e-05
Cis regulatory region sequence specific dna binding 72 129 -4.30735728410892 1.6521662666413306e-05
Ccr3 chemokine receptor binding 0 1 4.306930884021927 1.6553530497009916e-05
Vasopressin receptor activity 1 1 -4.287770738120997 1.8047522122977e-05
Androstan 3 alpha 17 beta diol dehydrogenase activity 0 1 4.280557228660355 1.8642593818007924e-05
Phosphatidylcholine sterol o acyltransferase activator activity 1 1 -4.274952686210842 1.9117788952360822e-05
L alanine transmembrane transporter activity 0 1 4.234421242723698 2.291410707178088e-05
Alanine transmembrane transporter activity 0 1 4.234421242723698 2.291410707178088e-05
Oxidoreductase activity acting on nad p h oxygen as acceptor 0 1 4.229279634045061 2.3444079385370745e-05
Nad p h oxidase h2o2 forming activity 0 1 4.229279634045061 2.3444079385370745e-05
Rna polymerase iii general transcription initiation factor activity 1 1 -4.222624316806087 2.4147413036246235e-05
Adenylate cyclase activity 1 1 -4.20022119684327 2.666543409990396e-05
Udp n acetylglucosamine transmembrane transporter activity 1 1 -4.1812179611834 2.8995175056056866e-05
Ammonia lyase activity 1 1 -4.1725658907582135 3.011884581649582e-05
Atp dependent activity acting on rna 46 58 4.159834778040325 3.184778943055022e-05
Phosphatidylcholine flippase activity 1 1 -4.146556013865944 3.375136383532151e-05
Translation initiation factor activity 35 40 4.131884451641612 3.5980128851864634e-05
Alcohol dehydrogenase activity zinc dependent 0 1 4.125791802518701 3.694613951066295e-05
Fucose binding 1 1 -4.092544963208501 4.266644779482576e-05
Mrna 5 utr binding 16 22 4.090019377373026 4.313371512698616e-05
Ribonucleoprotein complex binding 67 113 4.088740059247888 4.337225447037518e-05
Oleate transmembrane transporter activity 0 1 4.08578576117633 4.392789799823049e-05
Tfiib class transcription factor binding 0 1 4.084913970672855 4.409315003539582e-05
Caspase binding 1 1 -4.084675576655104 4.413844132056255e-05
Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 17 23 4.0769387605587015 4.563250489386661e-05
Oxidoreductase activity acting on metal ions oxygen as acceptor 1 1 -4.072419552606547 4.652727257914435e-05
Steroid hydroxylase activity 1 1 -4.005570745409294 6.186791303264272e-05
Camp response element binding protein binding 1 1 -4.001153928920243 6.303433431087413e-05
Voltage gated calcium channel activity involved in cardiac muscle cell action potential 1 1 -3.984348600063589 6.766548074610412e-05
Thyroid hormone transmembrane transporter activity 1 1 -3.972830608689836 7.102355796995141e-05
Ligase activity 62 124 3.965790308589581 7.315315428479963e-05
Immunoglobulin receptor binding 0 1 3.945147056067372 7.975101999724288e-05
Neuropeptide binding 1 1 -3.931054817880084 8.457398383709958e-05
Mrna 3 utr binding 42 56 3.922691633394368 8.756519554742326e-05
Telethonin binding 1 1 -3.88548420307429 0.0001021261339761
Mhc class ii protein binding 1 1 -3.863053683142911 0.0001119783874528
Rna binding involved in posttranscriptional gene silencing 0 1 3.829130797174893 0.0001285966501574
Calcitonin family receptor activity 1 1 -3.8270377263035895 0.0001296946433742
Mechanosensitive ion channel activity 1 1 -3.808066253695781 0.0001400577523265
General transcription initiation factor activity 15 23 -3.7947929420493134 0.0001477667220251
Fructose transmembrane transporter activity 1 1 -3.790863897893617 0.0001501242061543
Aryl sulfotransferase activity 2 2 -3.773415919911 0.0001610275040628
Oligosaccharide binding 0 1 3.76599291132434 0.0001658884983872
Acetylesterase activity 1 1 -3.765447414267077 0.0001662511118145
Short chain carboxylesterase activity 1 1 -3.765447414267077 0.0001662511118145
Snorna binding 22 32 3.749650382153587 0.0001770812795736
Oxidoreductase activity acting on the aldehyde or oxo group of donors 16 26 3.74868503058788 0.0001777641653037
G protein coupled receptor kinase activity 1 1 -3.733566049248062 0.0001887876563353
Alpha 2a adrenergic receptor binding 1 1 -3.733566049248062 0.0001887876563353
Helicase activity 78 117 3.713172752375607 0.0002046770724193
Rrna binding 31 56 3.7082350218460505 0.000208708905165
Collagen receptor activity 1 1 -3.7043088000755566 0.0002119679167345
Protein serine threonine tyrosine kinase activity 80 158 -3.694827654968549 0.0002200359844242
Bile acid transmembrane transporter activity 1 2 -3.671655221109386 0.0002409846444533
Transmembrane receptor protein tyrosine kinase adaptor activity 1 1 -3.659305649732508 0.0002528995584727
Carbonate dehydratase activity 1 1 -3.658384643038667 0.0002538099345317
Delta catenin binding 1 1 -3.6528564295164583 0.0002593392478198
Myosin heavy chain binding 1 1 -3.6491688820370345 0.0002630901102813
C x c chemokine binding 0 1 3.648382710654559 0.0002638963302747
Insulin like growth factor ii binding 0 1 3.625398355975969 0.0002885163622186
N acylsphingosine amidohydrolase activity 0 1 3.6198727361518457 0.0002947479466683
Bile acid binding 0 1 3.600504375528245 0.0003176004836762
Rna polymerase ii general transcription initiation factor activity 15 20 -3.5986230581567766 0.0003199064699623
Death receptor activity 0 1 3.589416643069814 0.0003314187834599
Tumor necrosis factor activated receptor activity 0 1 3.589416643069814 0.0003314187834599
Lipoprotein lipase activity 1 1 -3.562962054763152 0.000366693700585
Chitinase activity 1 1 -3.558301454579249 0.0003732607818642
Lactate dehydrogenase activity 1 2 3.5498082108682034 0.000385511897416
L lactate dehydrogenase activity 1 2 3.5498082108682034 0.000385511897416
Protein kinase activity 90 198 -3.539981100226634 0.0004001556875694
Gap junction channel activity involved in cardiac conduction electrical coupling 2 2 -3.539806960431057 0.0004004198059641
Gap junction channel activity involved in cell communication by electrical coupling 2 2 -3.539806960431057 0.0004004198059641
Adenosine receptor binding 1 1 -3.536828404984232 0.0004049626833939
Oxidoreductase activity acting on ch oh group of donors 45 69 3.5329489500847022 0.0004109518172759
3 beta hydroxy delta5 steroid dehydrogenase activity 0 1 3.5253763315058952 0.0004228815728373
Protein serine kinase activity 73 144 -3.508188754187171 0.0004511688177042
Chondroitin sulfotransferase activity 1 1 -3.500288111185843 0.0004647555522394
3 5 cyclic amp phosphodiesterase activity 1 1 -3.491832466256364 0.000479719036412
3 5 cyclic gmp phosphodiesterase activity 1 1 -3.491832466256364 0.000479719036412
Atp hydrolysis activity 112 230 3.489359846940524 0.000484178881589
Protein phosphatase 2b binding 1 2 -3.4640784978087416 0.0005320512274544
Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity 0 1 3.4505096557210897 0.0005595291515672
Inorganic phosphate transmembrane transporter activity 0 1 3.39770274586557 0.0006795421349876
Ubiquitin like protein transferase activity 73 152 -3.397216641881963 0.0006807504962638
Complement component c3b binding 0 1 3.388237888056115 0.000703432258712
Neuropeptide receptor activity 1 1 -3.3801510756809896 0.0007244599645934
Inhibin binding 1 1 -3.374431275192746 0.0007396838285651
Activin activated receptor activity 1 1 -3.374431275192746 0.0007396838285651
Activin receptor activity type i 1 1 -3.374431275192746 0.0007396838285651
Transmembrane receptor protein serine threonine kinase activity 1 1 -3.374431275192746 0.0007396838285651
Natural killer cell lectin like receptor binding 2 2 -3.351564287508628 0.0008035637938195
Retinal dehydrogenase activity 0 2 3.33272338779565 0.0008600039925554
Amide binding 79 141 3.3274298109961493 0.0008765106666308
3 hydroxyacyl coa dehydrogenase activity 5 7 3.3253859197654063 0.0008829622558552
Double stranded rna binding 30 48 3.322953385552734 0.0008906979719958
Atp dependent activity 145 317 3.3142686496747857 0.0009188318040322
Complement component c1q complex binding 1 2 3.3017635759160093 0.0009607901713282
Protein serine threonine kinase activity 78 165 -3.2992396605412297 0.0009694710478225
Benzodiazepine receptor binding 1 1 -3.295855383114874 0.0009812251138914
Protein glutamic acid ligase activity 1 1 -3.294892444979036 0.0009845935668635
Interleukin 2 receptor binding 0 1 3.269979252390792 0.0010755537276949
Inositol 1 4 5 trisphosphate binding 1 1 -3.268849964753823 0.0010798554501953
Calcium release channel activity 1 1 -3.268849964753823 0.0010798554501953
Intracellular ligand gated ion channel activity 1 1 -3.268849964753823 0.0010798554501953
Ligand gated calcium channel activity 1 1 -3.268849964753823 0.0010798554501953
Acyltransferase acyl groups converted into alkyl on transfer 2 3 3.2684220791685594 0.0010814895201949
Toll like receptor binding 1 2 -3.254374073897863 0.0011364253003809
Store operated calcium channel activity 1 1 -3.2533779757572807 0.0011404169326558
Potassium proton antiporter activity 1 1 -3.249505378929946 0.0011560589187284
Potassium ion antiporter activity 1 1 -3.249505378929946 0.0011560589187284
Galactoside binding 1 2 3.243537604878603 0.001180552257318
Phospholipase d activity 1 2 3.231499975817191 0.0012314233435399
S100 protein binding 7 8 3.2268836778303225 0.0012514632468731
Guanosine diphosphatase activity 1 2 -3.226632671562735 0.0012525614797609
Histone h3 tri di methyl lysine 27 demethylase activity 1 2 -3.221336697741855 0.0012759415312095
Rna polymerase i core binding 2 2 -3.2198393173886024 0.0012826246742694
Phosphate ion transmembrane transporter activity 1 1 -3.2194301182522125 0.0012844566349037
Protein cysteine s stearoyltransferase activity 2 2 -3.214629769767057 0.0013061286237245
Heat shock protein binding 38 66 3.198180741212988 0.0013829757169077
Calcium cation antiporter activity 1 2 3.195284068236002 0.0013969327137017
Interferon receptor activity 1 1 -3.1872919388617413 0.0014361174009036
Protein folding chaperone 19 29 3.175404069017972 0.0014962798634172
Proteasome activating activity 5 6 3.149250796163616 0.0016368965079727
Poly pyrimidine tract binding 10 18 3.14469916572709 0.0016625769926688
Metallopeptidase activity 35 53 3.144116273370503 0.0016658923365462
Transcription elongation regulator activity 1 2 3.1432772631289296 0.0016706750934378
Metal dependent deubiquitinase activity 6 7 3.142729105376377 0.0016738066724859
Nad binding 21 37 3.137771494406253 0.0017023753519276
Lysine n acetyltransferase activity acting on acetyl phosphate as donor 2 2 -3.1316959955067096 0.0017379973647599
Hmg box domain binding 2 2 -3.1202808920770617 0.0018067865826711
Sulfur amino acid transmembrane transporter activity 1 1 -3.1186971732530577 0.0018165255461588
Inositol bisphosphate phosphatase activity 2 3 -3.117955518062247 0.0018211028661909
Superoxide dismutase activity 0 1 3.11195705272971 0.0018585153448467
Aldehyde dehydrogenase nad p plus activity 5 8 3.0942809764345465 0.0019729054471921
Protein containing complex binding 212 572 3.0904572650222737 0.0019984856130026
Inositol hexakisphosphate kinase activity 2 2 -3.0868212545377425 0.0020230920838715
Inositol 1 3 4 5 6 pentakisphosphate kinase activity 2 2 -3.0868212545377425 0.0020230920838715
Serine type exopeptidase activity 6 7 3.0838345591427028 0.0020435119958783
Phosphatidylinositol n acetylglucosaminyltransferase activity 1 1 -3.074293550897597 0.0021100170223671
Mrna 3 utr au rich region binding 8 13 3.069973842281021 0.0021407751942761
Sialyltransferase activity 2 2 -3.0682710282044985 0.0021530125216804
Beta galactoside cmp alpha 2 3 sialyltransferase activity 2 2 -3.0682710282044985 0.0021530125216804
Lipopolysaccharide immune receptor activity 0 1 3.06190199168988 0.002199354521009
Phosphatidylcholine floppase activity 0 1 3.0530380317571986 0.0022653722567409
Lipid phosphatase activity 1 2 -3.0469970258153998 0.002311399967954
Transketolase or transaldolase activity 2 3 3.046842666578953 0.0023125872075806
Oxysterol binding 0 1 3.0392312581237837 0.002371827096975
Lactate transmembrane transporter activity 0 1 3.0362697466258584 0.0023952497271144
Double stranded rna adenosine deaminase activity 1 2 3.0338979551335603 0.0024141607397911
Butyrate coa ligase activity 1 1 -3.033625280326386 0.0024163435951094
C c chemokine binding 2 2 -3.030154435315646 0.0024442871915799
G protein coupled chemoattractant receptor activity 2 2 -3.030154435315646 0.0024442871915799
Metallodipeptidase activity 0 1 3.0204575986618813 0.0025239304451776
Bmp receptor binding 1 1 -3.0186958495164826 0.0025386525534485
Rna polymerase ii activity 1 2 3.0118530039810096 0.0025965830199814
Growth hormone receptor binding 2 2 -3.010583519447056 0.0026074622742493
Threonine type endopeptidase activity 6 8 3.000305666191061 0.0026970879727028
Large ribosomal subunit rrna binding 3 4 2.9967736617156424 0.0027285321420573
Signal sequence binding 21 34 2.9941971673008894 0.0027516806289729
Poly a binding 9 13 2.9794747563530124 0.0028874302026355
Poly purine tract binding 11 18 2.96075620126315 0.0030688475957263
Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity 4 5 2.9520319220583904 0.0031569029287774
Endopeptidase regulator activity 19 31 2.951478491541337 0.0031625657122777
Fatz binding 1 1 -2.9416256075520524 0.0032649440058105
5alpha androstane 3beta 17beta diol dehydrogenase activity 1 1 -2.938608119774545 0.0032968964239765
Coreceptor activity involved in wnt signaling pathway 0 1 2.929964805283348 0.0033900039690224
Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway 0 1 2.929964805283348 0.0033900039690224
Carbohydrate phosphatase activity 0 1 2.926965182265385 0.0034228719768032
Fructose 2 6 bisphosphate 2 phosphatase activity 0 1 2.926965182265385 0.0034228719768032
Transmembrane receptor protein phosphatase activity 1 2 -2.9227827692418 0.003469184569476
Patched binding 0 1 2.9169588664263038 0.0035346238298124
Snrna binding 24 38 2.9090161995361683 0.0036256807236363
Sulfate transmembrane transporter activity 1 2 2.9088178728200336 0.0036279814508439
Succinate transmembrane transporter activity 1 2 2.9088178728200336 0.0036279814508439
Neuropeptide hormone activity 2 2 -2.905703046823975 0.0036642901928525
Hexokinase activity 1 2 2.8989831291578727 0.0037437503792627
Sumo polymer binding 2 2 -2.8930622830129886 0.0038150563687393
G protein coupled opioid receptor activity 0 1 2.877822656669308 0.0040043017949231
1 4 alpha oligoglucan phosphorylase activity 2 3 2.8757835656666804 0.0040302595714516
Rna stem loop binding 6 9 2.86194578005924 0.004210489297884
Structural constituent of nuclear pore 15 22 2.8615851165255903 0.0042152830020734
Glutathione hydrolase activity 1 1 -2.851631004813968 0.0043495559138797
Hypoglycin a gamma glutamyl transpeptidase activity 1 1 -2.851631004813968 0.0043495559138797
Nucleobase transmembrane transporter activity 1 2 2.839739509338527 0.0045150386596248
Oxidative phosphorylation uncoupler activity 1 2 2.839739509338527 0.0045150386596248
Glycerophosphodiester phosphodiesterase activity 1 1 -2.838402757854521 0.0045339932171679
Water transmembrane transporter activity 0 1 2.836487204095518 0.0045612806086319
Water channel activity 0 1 2.836487204095518 0.0045612806086319
Ubiquitin like protein ligase activity 50 104 -2.833746612150293 0.0046005794926884
Molecular transducer activity 41 80 -2.830824554708616 0.0046428180541666
Dna n glycosylase activity 2 6 2.8194595737400467 0.004810458995716
Atpase coupled lipid transmembrane transporter activity 1 3 -2.812389005395031 0.004917499191257
Channel activator activity 1 1 -2.8047275586104994 0.0050359125806287
Small protein activating enzyme binding 2 3 2.7974461599825737 0.0051508351068565
Kinase activity 114 280 -2.7951074434062804 0.0051882468937298
Ribosome binding 27 52 2.792899450036584 0.0052237926865696
C3hc4 type ring finger domain binding 2 3 2.787287278310964 0.0053151337181196
Metalloaminopeptidase activity 9 13 2.787147924700737 0.0053174200125059
Type 5 metabotropic glutamate receptor binding 2 3 -2.78159997563015 0.0054091667348084
5 3 exodeoxyribonuclease activity 1 2 2.7737406261254844 0.0055415841146464
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen 0 1 2.7705492090903023 0.005596184343322
Phosphatidylserine 1 acylhydrolase activity 0 1 2.767493843957189 0.0056489112304658
Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity 4 7 -2.75916968553984 0.005794843674721
Single stranded rna binding 25 53 2.74927224663543 0.0059727754636804
Fatty acid transmembrane transporter activity 0 2 2.7393696079259064 0.0061557127130551
Transcription regulator activity 141 343 -2.734003522312897 0.0062569375084891
Co receptor binding 1 1 -2.7318055315229577 0.0062988307836895
Phosphatidylinositol bisphosphate phosphatase activity 6 13 -2.7213427601269795 0.0065017308072443
Narrow pore channel activity 1 1 -2.7194169484330963 0.0065397115468082
Atp dependent protein binding 2 3 2.708160383363008 0.0067657317946085
Phosphatidylinositol 3 5 bisphosphate phosphatase activity 5 9 -2.706755554022086 0.0067944265954396
Threonine type peptidase activity 6 10 2.702393045679205 0.0068842328894445
Tripeptide transmembrane transporter activity 1 3 -2.6987078638092656 0.0069609251644651
Glutathione transmembrane transporter activity 1 3 -2.6987078638092656 0.0069609251644651
D glucose transmembrane transporter activity 2 3 -2.6987000172409794 0.0069610892747584
Sugar transmembrane transporter activity 2 3 -2.6987000172409794 0.0069610892747584
Dehydroascorbic acid transmembrane transporter activity 1 2 -2.6921895424869287 0.0070984590104705
Ribonucleotide binding 309 910 2.692144066234372 0.0070994270502138
Death receptor binding 4 7 -2.690056601797762 0.0071439900849159
U3 snorna binding 9 10 2.689068743216125 0.0071651662183831
Complement binding 2 3 2.683342788646016 0.0072890236280425
Selenium binding 1 2 -2.677123265898855 0.0074257309805125
Peroxiredoxin activity 5 7 2.675745774182882 0.0074563180633946
Hydrolase activity acting on acid anhydrides 160 401 2.673576709169474 0.0075047110529407
Trna binding 26 54 2.6729942977331693 0.00751775283458
Translation elongation factor activity 11 15 2.6676941968310457 0.0076373737567949
Signal recognition particle binding 4 6 2.6619162759597925 0.0077697201724926
Glutathione disulfide oxidoreductase activity 1 3 2.661049697524321 0.007789745855864
Calcium dependent protein kinase activity 8 13 -2.650577055464301 0.0080354395421295
Polysome binding 0 2 2.64837861218555 0.0080878889083864
Abc type xenobiotic transporter activity 3 6 -2.6323805613440183 0.0084788829486397
Ap 1 adaptor complex binding 2 2 -2.631400502078587 0.0085033762102613
Exopeptidase activity 24 41 2.631159034325085 0.0085094205846767
Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity 2 2 -2.630467615984424 0.0085267492908611
Sodium chloride symporter activity 0 1 2.6288934829402235 0.0085663188183249
Anion sodium symporter activity 0 1 2.6288934829402235 0.0085663188183249
Cadherin binding involved in cell cell adhesion 9 12 2.628312728531697 0.0085809588482028
Apolipoprotein a i binding 1 2 2.6245705616597395 0.0086758313905739
Peptide binding 53 101 2.6238900626080865 0.008693183998778
Identical protein binding 271 770 2.620960336442211 0.0087682462679412
5s rrna binding 4 7 2.6203609092794284 0.0087836753188588
Extracellular matrix protein binding 1 1 -2.6175469765055834 0.008856429694489
Unfolded protein binding 38 80 2.6114836166002746 0.0090150307293241
Pre mrna 5 splice site binding 0 1 2.607137779898713 0.009130261364576
Ankyrin binding 2 3 2.6058870403474987 0.0091636677094846
Fructose 6 phosphate binding 2 3 2.6041583144013822 0.0092100203269369
Phosphofructokinase activity 2 3 2.6041583144013822 0.0092100203269369
Fructose binding 2 3 2.604158314401358 0.0092100203269376
Virion binding 1 2 2.597769015939096 0.0093831588895989
Oxo acid lyase activity 0 1 2.5967593633309844 0.0094107827485578
Ubiquitin like protein specific endopeptidase activity 2 2 -2.5940032013888525 0.0094865603575207
Isocitrate dehydrogenase activity 3 5 2.5928987048283134 0.0095170796774728
Single stranded dna binding 45 79 2.590474818436186 0.0095843633358634
Nucleoside triphosphatase regulator activity 61 161 -2.5889204250186424 0.0096277339882111
Oxidoreductase activity 172 337 2.586746283277966 0.0096886903543254
U2 snrna binding 4 5 2.58426008392711 0.0097588173073117
Sphingosine 1 phosphate receptor activity 1 1 -2.5819123027415585 0.0098254548947158
Bioactive lipid receptor activity 1 1 -2.5819123027415585 0.0098254548947158
Adenyl nucleotide binding 260 751 2.5813421025503533 0.0098417000825101
Chromatin insulator sequence binding 1 1 -2.5798114322225123 0.00988542779328
Potassium channel inhibitor activity 3 6 -2.576814552352152 0.0099715432401032
Calmodulin dependent protein kinase activity 6 10 -2.576132537936286 0.0099912340414005
Myosin light chain binding 1 2 -2.5758027885477826 0.010000766826391
Phosphorylation dependent protein binding 1 2 -2.5755511826274 0.0100080459957063
Gtpase activator activity 34 94 -2.573926211540943 0.0100551715255572
Receptor antagonist activity 0 1 2.57180229659712 0.0101170647556316
Igg binding 1 1 -2.566142983267257 0.0102836427695338
Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity 2 3 -2.564653948488008 0.0103278751852919
Myosin binding 11 27 -2.5644348940336013 0.0103343965584665
Receptor serine threonine kinase binding 2 2 -2.563964107441989 0.0103484245405351
Oligopeptide transmembrane transporter activity 2 4 -2.5616915884776192 0.0104163771625682
Intramolecular oxidoreductase activity 15 29 2.56025700636987 0.0104594780384785
Actin filament binding 51 99 2.559879506513912 0.0104708460582343
Phosphatidylserine floppase activity 1 1 -2.558773858320192 0.0105042047859589
Phosphatidylserine flippase activity 1 1 -2.558773858320192 0.0105042047859589
Carbohydrate transmembrane transporter activity 3 4 -2.5587610827112184 0.0105045907932455
Camp response element binding 4 4 -2.558408968863756 0.010515234667747
N acetyllactosamine synthase activity 2 2 -2.555496130150918 0.010603654016442
Icosanoid binding 1 1 -2.5545600385531024 0.0106322091841679
Inositol phosphate phosphatase activity 4 9 -2.5536972712137724 0.0106585881590097
Disulfide oxidoreductase activity 18 27 2.54981196121411 0.0107781034542586
Serine type carboxypeptidase activity 4 5 2.546659106385159 0.0108759619359979
Deoxycytidine deaminase activity 1 1 -2.5419059521919616 0.0110249834556368
Cytidine deaminase activity 1 1 -2.5419059521919616 0.0110249834556368
Abc type glutathione s conjugate transporter activity 1 3 -2.5146429196071964 0.0119152997291602
G protein coupled receptor activity 8 11 -2.5139912951995558 0.0119373380284646
7s rna binding 5 7 2.513551963674602 0.0119522168540093
Inositol 1 4 5 trisphosphate 5 phosphatase activity 3 4 -2.512140190055756 0.0120001407122269
L lysine transmembrane transporter activity 2 3 -2.5093018659439115 0.0120970058271485
Ribosomal protein s6 kinase activity 1 2 2.502871661644885 0.0123190205947234
1 phosphatidylinositol 3 kinase regulator activity 1 1 -2.497467188970362 0.0125084040119829
Ubiquitin protein transferase inhibitor activity 6 8 2.4960927314020678 0.0125569770406435
Eukaryotic initiation factor 4e binding 2 4 2.4955031132383643 0.0125778651535308
Hsp70 protein binding 13 20 2.4918214732663606 0.0127089899290275
Superoxide generating nadph oxidase activator activity 1 1 -2.4879142862587225 0.0128494697540042
Pyruvate dehydrogenase activity 3 5 2.486952601173732 0.0128842563910946
Opioid receptor binding 1 1 -2.4868521912137687 0.0128878932788025
Corticotropin releasing hormone receptor binding 1 1 -2.4868521912137687 0.0128878932788025
Histone arginine n methyltransferase activity 2 3 2.4823396254539003 0.0130522806723609
Protein arginine omega n asymmetric methyltransferase activity 2 3 2.482339625453888 0.0130522806723614
Cytochrome b5 reductase activity acting on nad p h 1 3 2.477631881468588 0.0132257520860119
Cis trans isomerase activity 24 33 2.477117342582908 0.0132448348849827
Basic amino acid transmembrane transporter activity 3 4 -2.4688956143219087 0.013553074746615
Heparan sulfate sulfotransferase activity 0 1 2.4681252456026392 0.0135822787604029
Phosphatidic acid transfer activity 2 2 -2.466539165613898 0.01364258079892
Gap junction channel activity 2 3 -2.465179402931491 0.0136944665132803
Double stranded telomeric dna binding 4 6 2.464094563319993 0.0137359866527702
Heparan sulfate proteoglycan binding 2 3 -2.4630894234861547 0.0137745556222905
Cytokine receptor activity 3 3 -2.4618797337612484 0.0138211003150747
Immune receptor activity 3 3 -2.4618797337612484 0.0138211003150747
Aminoacyl trna editing activity 7 10 2.4602647086344547 0.013883457365996
L arginine transmembrane transporter activity 1 2 -2.455834206558154 0.0140557987663454
C acyltransferase activity 10 11 2.446941266341537 0.0144074314939632
Map kinase tyrosine serine threonine phosphatase activity 0 1 2.4417587970242964 0.0146159082597074
Protein tyrosine threonine phosphatase activity 0 1 2.4417587970242964 0.0146159082597074
Zinc ion transmembrane transporter activity 4 6 -2.4375952861819346 0.0147853169599856
Acetyl coa c acyltransferase activity 5 8 2.4327863721040104 0.0149831380002429
Retinoic acid responsive element binding 2 2 -2.431265925654278 0.0150461668663726
Fibroblast growth factor receptor binding 1 1 -2.429302285671386 0.0151279134634134
Type 1 fibroblast growth factor receptor binding 1 1 -2.429302285671386 0.0151279134634134
Protein tyrosine kinase activity 18 34 -2.427514974866378 0.0152026592233209
Protein hormone receptor activity 2 2 -2.4197945050080683 0.0155292801023345
Proteoglycan binding 5 10 -2.4179606563311045 0.0156077642835688
Vitamin d binding 1 2 2.4117184571117782 0.0158775368580488
Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor 1 2 -2.411549769133205 0.0158848836947007
Racemase and epimerase activity 7 11 -2.40966875866928 0.01596700974266
Cyclohydrolase activity 2 3 2.4067215891531104 0.0160964356908797
Wnt protein binding 1 1 -2.3917946214408343 0.0167662214150445
Hsp90 protein binding 14 22 2.3903231247656422 0.0168335552671892
Peptidase regulator activity 22 40 2.386046854639434 0.0170305811098854
Porin activity 3 4 2.384730213267101 0.0170916503995286
Atpase inhibitor activity 0 1 2.384553119993896 0.0170998790932079
Erbb 3 class receptor binding 0 1 2.383490487527661 0.0171493276787788
Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels 0 1 2.383490487527661 0.0171493276787788
Tumor necrosis factor binding 1 1 -2.3778217001862725 0.0174152445323749
Neuroligin family protein binding 0 1 2.371793707334185 0.0177019711560402
Oxidoreductase activity acting on metal ions nad or nadp as acceptor 3 3 -2.3667571687987574 0.0179447023903049
Inositol trisphosphate phosphatase activity 3 6 -2.3644364719987787 0.0180575240438574
Chaperone binding 29 58 2.3636478528497267 0.0180960042736257
Crossover junction endodeoxyribonuclease activity 2 3 -2.3605851288837787 0.0182461300216358
U1 snrna binding 6 7 2.360578539542705 0.0182464541838278
Alpha glucosidase activity 2 3 2.3509505795215984 0.0187255207401539
1 phosphatidylinositol 4 phosphate 3 kinase activity 0 1 2.3504901434763754 0.0187487042105831
Phosphatidylinositol 4 5 bisphosphate 3 kinase activity 0 1 2.3504901434763754 0.0187487042105831
Phosphatidylinositol bisphosphate kinase activity 0 1 2.3504901434763754 0.0187487042105831
Tfiid class transcription factor complex binding 4 7 2.348345306799951 0.0188570303381891
Oxidoreductase activity acting on a sulfur group of donors 21 34 2.343739569561029 0.0190914969268152
Translation initiation factor binding 15 21 2.340807966322785 0.0192420614600461
Aminopeptidase activity 11 17 2.336567009082921 0.0194617095558333
Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides 9 23 -2.334503246244304 0.0195693862847758
Nfat protein binding 1 2 -2.3287156458995137 0.0198741347009039
Gap junction hemi channel activity 1 2 -2.321811318821773 0.0202430975193417
Dolichyl phosphate mannose protein mannosyltransferase activity 1 2 2.32064058706585 0.0203062497518315
Intramolecular oxidoreductase activity transposing c c bonds 3 8 2.320592185145104 0.0203088643696571
L histidine transmembrane transporter activity 1 2 -2.3204587699518644 0.0203160728302895
Proton transmembrane transporter activity 27 48 2.3189666945537217 0.0203968422793305
Glucosidase activity 4 5 2.317942409064456 0.0204524512009447
Choline transmembrane transporter activity 2 2 -2.313919867630972 0.0206721180881306
Microtubule severing atpase activity 4 4 -2.313232234596936 0.0207098741852533
C4 dicarboxylate transmembrane transporter activity 4 6 2.310589275713061 0.0208555521697122
Endopolyphosphatase activity 1 2 -2.309419129835528 0.020920334500166
Ubiquitin like modifier activating enzyme activity 5 9 2.301768783825447 0.0213482148418366
G protein beta subunit binding 0 3 2.2987449031742218 0.0215194291059348
Ligase activity forming carbon carbon bonds 6 7 2.292530158157808 0.0218750693461917
Xenobiotic transmembrane transporter activity 3 8 -2.2915701304839566 0.0219304607263941
Cell adhesion mediator activity 15 27 2.284442497543572 0.0223455383874429
Atp gated ion channel activity 1 1 -2.275028622928915 0.0229042128440539
Nad p plus protein arginine adp ribosyltransferase activity 0 1 2.273407511988085 0.0230016338792231
Rage receptor binding 1 3 2.2720578829759104 0.0230830144888982
Metalloexopeptidase activity 16 26 2.267614995334568 0.0233526829131014
Supercoiled dna binding 4 5 2.256421028740975 0.0240442758993588
Metalloendopeptidase activity 13 18 2.252938842876799 0.0242630053107646
Interleukin 1 binding 1 1 -2.249961139103131 0.0244514122806127
Snrnp binding 5 6 2.246394997707669 0.0246787184632197
Cyclase activity 1 3 -2.2457205089499634 0.0247219156778186
Nucleoside triphosphate diphosphatase activity 4 7 2.243826019969536 0.0248435975654346
Peptide transmembrane transporter activity 3 7 -2.233866980704697 0.0254918267343331
Peptidase activity 78 177 2.231985744614046 0.0256159051188871
N acetylgalactosamine 4 o sulfotransferase activity 0 1 2.2314019173915454 0.0256545179685305
Telomeric dna binding 11 24 2.228910437548126 0.0258198645086631
Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor 2 3 2.227691060896671 0.0259011235297859
Atp dependent peptidase activity 4 6 2.221681427331711 0.0263048425746876
Inositol trisphosphate kinase activity 1 1 -2.218254027038417 0.0265375168547783
U4 snrna binding 5 6 2.217956043364974 0.0265578296782793
C palmitoyltransferase activity 1 2 2.214276571543488 0.026809759258193
Catalytic activity acting on rna 140 267 2.210403322804629 0.0270771834048053
Sequence specific dna binding 112 280 -2.209983132278034 0.0271063329662402
N acyltransferase activity 14 41 -2.2075928803286757 0.0272726658991664
Cell cell adhesion mediator activity 13 24 2.2049851606336346 0.0274551358598837
Peptide receptor activity 7 8 -2.2018528036318963 0.0276757077455409
Mdm2 mdm4 family protein binding 5 6 2.199284205924172 0.0278577200372245
Arachidonate coa ligase activity 3 7 2.194455888389494 0.0282026518355287
Platelet derived growth factor receptor binding 1 1 -2.194125854608868 0.0282263630344545
2 acylglycerol o acyltransferase activity 0 1 2.191388481716399 0.0284236919144049
Translation repressor activity mrna regulatory element binding 5 7 2.190669337103536 0.0284757295571878
Ribosomal small subunit binding 8 13 2.1878665621241478 0.0286793236113391
Structural constituent of eye lens 2 3 2.1871791494776525 0.0287294483845619
Neuregulin binding 2 2 -2.1861358542830125 0.0288056675345371
Transforming growth factor beta binding 2 2 -2.1861358542830125 0.0288056675345371
Retinal binding 3 5 -2.183457201410412 0.0290021574539036
Deoxyribonuclease i activity 0 1 2.182716369382028 0.0290567036891107
Wd40 repeat domain binding 3 4 2.172574367626886 0.0298123668173877
Neurotrophin binding 0 2 2.171652108440458 0.0298819134233365
Ceramide 1 phosphate binding 2 2 -2.169418117178665 0.030050954737792
Ceramide 1 phosphate transfer activity 2 2 -2.169418117178665 0.030050954737792
Phosphatidylinositol phosphate 5 phosphatase activity 3 7 -2.1690474616321183 0.0300790807937958
Neurotransmitter binding 0 1 2.164264032708266 0.0304440914406247
Angiotensin receptor binding 3 3 -2.160361933889207 0.0307446618718092
Protein n terminus binding 33 61 2.1567836996240617 0.0310225217726074
Aminoacyltransferase activity 3 3 -2.155740372065556 0.0311039438363101
Arylesterase activity 1 2 2.1437224925028278 0.0320551288669497
Disordered domain specific binding 11 20 2.1323017695530684 0.0329820466827723
Oxidoreductase activity acting on metal ions 4 4 -2.1317949131293825 0.0330237100140415
4 iron 4 sulfur cluster binding 16 29 2.1276943764121485 0.0333624314847527
Protein arginine omega n monomethyltransferase activity 1 3 2.119659218560981 0.0340347945317138
H3 histone acetyltransferase activity 3 4 -2.1165608248983934 0.0342971378687706
Interleukin 1 receptor binding 0 2 2.113089500998039 0.0345931081309247
Single stranded dna 3 5 exodeoxyribonuclease activity 1 2 2.111674937655509 0.0347143400971203
Ap 2 adaptor complex binding 4 5 -2.1083515368681667 0.0350005931375869
Alpha tubulin binding 7 17 -2.1023689581628764 0.0355209682158967
Lbd domain binding 0 1 2.1021578328420563 0.0355394522041292
Racemase and epimerase activity acting on carbohydrates and derivatives 4 7 -2.101103617937352 0.0356318713862076
Map kinase kinase kinase activity 6 8 -2.100122482014936 0.0357180681122752
Enoyl coa hydratase activity 5 7 2.099343741705673 0.0357866101186474
Phospholipid scramblase activity 1 4 -2.092603527970962 0.0363845613789275
Pyruvate transmembrane transporter activity 0 1 2.08575430028548 0.0370008849693652
Protein arginine n methyltransferase activity 3 6 2.080925286657507 0.0374407452152074
Importin alpha family protein binding 3 7 2.0789275538562686 0.0376240097145195
Cytokine activity 4 7 2.0704586205450632 0.0384094171911206
5 3 exonuclease activity 6 11 2.06986786897931 0.0384647195924721
Catalytic activity acting on a nucleic acid 195 390 2.0664858975495664 0.03878262264839
Salt transmembrane transporter activity 1 1 -2.065847883012709 0.0388428452040985
Box h aca snorna binding 3 5 2.0653339812222065 0.0388914104374618
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen 1 2 -2.0639246314218704 0.0390248629327025
Neuropeptide receptor binding 2 2 -2.0634867559513994 0.0390664048359354
3 phosphoadenosine 5 phosphosulfate binding 4 4 -2.04758977954948 0.0406002116365973
Retinol binding 3 4 -2.0468970428294453 0.0406681945182083
Map kinase phosphatase activity 1 2 2.0463225303334487 0.0407246484382031
Inositol tetrakisphosphate phosphatase activity 2 4 -2.0455101979833565 0.0408045848451139
Hydrolase activity acting on ether bonds 5 7 2.042929473976692 0.0410594201368943
Nf kappab inducing kinase activity 1 2 -2.038376720588013 0.0415122725700225
Amino acid proton symporter activity 0 1 2.036397142150779 0.0417104921881201
Phosphatidylinositol phosphate phosphatase activity 6 16 -2.034477045702119 0.0419035206687292
Mutsalpha complex binding 4 4 -2.032596368592149 0.0420933186966099
Mannosidase activity 4 9 -2.030405796219916 0.0423153079770746
Rna cap binding 8 14 2.028202238219568 0.0425396115760818
Mhc protein complex binding 6 9 2.0234745968339496 0.0430242400664777
K63 linked polyubiquitin modification dependent protein binding 7 11 -2.021050496288688 0.0432745380959136
Cyclin dependent protein serine threonine kinase regulator activity 5 14 -2.0181978617033263 0.0435706587662392
L serine transmembrane transporter activity 1 3 2.017910314318652 0.0436006026524278
Leukotriene c4 synthase activity 1 2 2.016938796781208 0.0437019007033074
Sh3 domain binding 19 44 -2.011472899682868 0.0442755300176354
Serine hydrolase activity 13 26 2.007104786426408 0.0447385066951895
C acetyltransferase activity 6 7 1.999749430154696 0.0455273276931342
Acetyl coa c acetyltransferase activity 3 6 1.995926723039927 0.0459418994589961
Cxcr chemokine receptor binding 1 2 1.9943616153531525 0.0461125501515509
Endodeoxyribonuclease activity producing 3 phosphomonoesters 3 4 -1.9929299723263352 0.0462691157621588
Flap endonuclease activity 2 4 1.9925711100783123 0.0463084313040307
Ubiquitin like protein ligase binding 75 166 1.9890543567578352 0.0466952035451186
Protein serine threonine phosphatase inhibitor activity 1 2 -1.9888537464160791 0.0467173483731322
Acetylcholine receptor binding 1 2 1.981581823077765 0.0475260632330183
Aminophospholipid flippase activity 2 2 -1.980482397823344 0.0476493493131617
Nucleocytoplasmic carrier activity 11 26 1.976482408243302 0.0481001662336524
Gamma aminobutyric acid transmembrane transporter activity 0 1 1.975780026350036 0.0481796965810183
Vascular endothelial growth factor activated receptor activity 1 1 -1.9718621616756 0.0486253438232657
Vascular endothelial growth factor binding 1 1 -1.9718621616756 0.0486253438232657
Ionotropic glutamate receptor binding 4 6 1.969750288734812 0.048866996403805
Oxygen sensor activity 1 3 1.960078679673044 0.0499865947767139
Stat family protein binding 5 5 -1.9591694325010165 0.0500929476435851
Ubiquitin protein transferase regulator activity 8 14 1.958963085267384 0.0501171100675803
14 3 3 protein binding 8 12 -1.9578087304269869 0.0502524606081473
Copper ion transmembrane transporter activity 2 2 -1.9533262911509996 0.0507809440770783
Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters 4 6 -1.9520649020685557 0.0509304995868027
T cell receptor binding 1 2 -1.9514006673916864 0.0510094021554898
Pyrimidine nucleoside transmembrane transporter activity 0 1 1.9503385949533036 0.0511357754307169
Nucleoside transmembrane transporter activity 0 1 1.9503385949533036 0.0511357754307169
Uridine transmembrane transporter activity 0 1 1.9503385949533036 0.0511357754307169
Extracellular matrix constituent conferring elasticity 1 1 -1.9482247002057973 0.0513880825504875
Map kinase kinase kinase kinase activity 2 2 -1.947281392560406 0.0515010082703994
Structural constituent of presynaptic active zone 0 2 1.93887052716998 0.0525171055624755
Sphingomyelin phosphodiesterase activity 2 3 -1.9385431975038607 0.0525569859366259
Phosphatidylinositol monophosphate phosphatase activity 5 9 -1.937788732015874 0.0526490030518553
Dna helicase activity 22 54 1.934546616134644 0.0530459563613971
Atp transmembrane transporter activity 4 7 1.9319980753228052 0.0533597434363182
Metal cluster binding 22 44 1.9315941921394333 0.0534096132658277
G protein coupled glutamate receptor binding 2 5 -1.9278929941134104 0.0538684373471753
Endodeoxyribonuclease activity producing 5 phosphomonoesters 3 6 1.918386613243268 0.0550620072082488
Guanyl nucleotide exchange factor activity 25 71 -1.9182385008373464 0.0550807764340195
Syndecan binding 1 2 -1.91496299914911 0.0554972224953429
Telomerase activity 1 3 1.9135400005358687 0.055678957770004
Rna directed dna polymerase activity 1 3 1.9135400005358687 0.055678957770004
Phosphatidylinositol 4 5 bisphosphate phosphatase activity 2 6 -1.9123756991723089 0.0558280226173111
Benzodiazepine receptor activity 0 1 1.9048556098401277 0.0567988428476693
Neurotransmitter receptor activity 0 1 1.9048556098401277 0.0567988428476693
Intramolecular oxidoreductase activity interconverting aldoses and ketoses 3 6 1.903401706366401 0.0569881485487668
Endopeptidase activity 43 100 1.9022392860458388 0.0571398789800807
Hyaluronic acid binding 0 2 1.8991659994823784 0.0575426536272019
Translation termination factor activity 1 3 1.898543894187684 0.0576244712777578
Isoprenoid binding 4 8 -1.8886113773717312 0.0589439213610194
Channel regulator activity 19 38 -1.883487236073272 0.0596343679991
Carbon carbon lyase activity 15 26 1.8834826779824037 0.059634985147801
Sumo transferase activity 6 12 -1.882922138738488 0.0597109204948287
Carbohydrate kinase activity 5 9 1.8795195087786276 0.0601735922763611
Protein serine threonine kinase activator activity 11 20 -1.8764625630094176 0.0605917907125701
O palmitoyltransferase activity 1 2 1.8758984203978848 0.0606692296048718
Low density lipoprotein particle receptor activity 3 5 -1.8740873979496244 0.0609183799823322
Atp dependent activity acting on dna 31 78 1.8736125798841048 0.0609838428771747
Cysteine type endopeptidase inhibitor activity 8 12 1.8724054504877563 0.0611505315494074
Alditol nadpplus 1 oxidoreductase activity 2 3 1.870827779708948 0.0613689558223813
Jun kinase kinase kinase activity 0 1 1.869243724258784 0.0615889136047806
Glycine binding 1 2 -1.8662698174177608 0.0620036253499498
Nad p plus nucleosidase activity 1 1 -1.8656270213155377 0.0620935664046795
Nadplus nucleosidase activity 1 1 -1.8656270213155377 0.0620935664046795
Potassium channel activity 2 2 -1.8653164546520151 0.0621370600494581
Ligand gated cation channel activity 2 2 -1.8653164546520151 0.0621370600494581
Nerve growth factor binding 0 1 1.8636706664253704 0.0623679671625339
Neurotrophin receptor activity 0 1 1.8636706664253704 0.0623679671625339
Triglyceride lipase activity 4 5 -1.861931946751812 0.0626126832975302
Bicarbonate transmembrane transporter activity 0 1 1.861440794752232 0.0626819541523215
Solute bicarbonate symporter activity 0 1 1.861440794752232 0.0626819541523215
Beta n acetylhexosaminidase activity 3 4 1.861170918885929 0.0627200437419754
Map kinase activity 3 7 -1.8593364207534917 0.0629794676307633
Folic acid transmembrane transporter activity 1 2 1.853070993942915 0.0638721836626712
Ubiquinol cytochrome c reductase activity 2 4 1.8503277315204496 0.0642663280471342
Oxidoreductase activity acting on diphenols and related substances as donors 2 4 1.8503277315204496 0.0642663280471342
Monosaccharide binding 18 39 1.849842687536212 0.0643362262966213
Single stranded dna helicase activity 9 17 1.8485018923732544 0.0645297708762782
Ligase activity forming carbon sulfur bonds 8 24 1.844081724110632 0.0651712309418797
1 phosphatidylinositol 4 phosphate 5 kinase activity 3 4 -1.8305340718804617 0.0671701167398237
Protein dimerization activity 97 365 1.8234102963370709 0.0682412720206928
Lyase activity 44 81 1.8195910762693903 0.0688213016521575
Testosterone dehydrogenase nadplus activity 0 2 1.819032992569931 0.0689063967550167
Testosterone dehydrogenase nad p activity 0 2 1.819032992569931 0.0689063967550167
Endopeptidase activator activity 3 5 1.81501237434517 0.0695220078584304
Zinc ion binding 90 269 -1.8144650364221335 0.0696061608759197
Phosphatidylinositol 3 4 bisphosphate binding 3 4 -1.81061926850072 0.0701998074267129
Biotin binding 2 5 1.8103085775134544 0.070247947630059
Chromo shadow domain binding 3 5 1.8098159766012512 0.0703243294939568
Nuclear localization sequence binding 11 20 1.7989381431057232 0.0720284660712664
Neurotransmitter receptor regulator activity 0 2 1.7983358117987074 0.0721238079190538
Udp glycosyltransferase activity 22 38 -1.7957523855882689 0.0725339063910452
Cgmp binding 1 2 -1.7924625551514992 0.0730589021286896
Aspartic type endopeptidase inhibitor activity 1 2 1.7893601994104311 0.0735568247919378
Alcohol dehydrogenase nad p plus activity 0 2 1.7802869113607729 0.0750290180484376
Phosphodiesterase i activity 1 3 1.7798685992132433 0.0750974676803322
U6 snrna binding 7 14 1.777287800761611 0.0755208997709102
Phospholipid transfer activity 7 9 -1.775866760675038 0.0757548807320533
Adp transmembrane transporter activity 3 5 1.7750498857438817 0.0758896505914599
Histone methyltransferase activity h3 k9 specific 1 4 -1.7737145728582475 0.0761103747065727
Dicarboxylic acid transmembrane transporter activity 4 8 1.7708440307411188 0.0765866416976139
Long chain fatty acid coa ligase activity 3 8 1.7675475116209585 0.0771365794817757
Protein kinase c activity 3 9 -1.7635191097665954 0.0778129771416795
P type potassium transmembrane transporter activity 1 2 1.7624023087751246 0.0780013488429851
Polynucleotide adenylyltransferase activity 4 6 -1.760358102965295 0.0783471083733906
Phosphatase regulator activity 15 42 -1.7600957034880738 0.0783915811545514
Protein transmembrane transporter activity 10 14 1.7531284394765336 0.0795799628846398
Protein disaggregase activity 2 4 1.7526270270611377 0.0796660489402052
Dead h box rna helicase binding 1 2 -1.7518922922746571 0.0797923301616116
Rna strand annealing activity 4 5 1.7461355633291458 0.0807873984155191
Chromatin binding 104 278 1.7441424313842968 0.0811342567532751
Nucleosome binding 24 48 1.7430013576711965 0.08133337766445
Mhc class ii protein complex binding 5 8 1.73772362588224 0.0822595236737413
Nucleosomal dna binding 20 29 1.7369610291985276 0.0823940498519313
Sumo ligase activity 5 8 -1.7362838142004329 0.0825136637172232
Nucleotide sugar transmembrane transporter activity 1 2 -1.7345780970950535 0.0828155617985246
Pyrimidine nucleotide sugar transmembrane transporter activity 1 2 -1.7345780970950535 0.0828155617985246
Lysine n methyltransferase activity 7 26 -1.7331477067800904 0.0830694188122884
Trna specific adenosine deaminase activity 1 2 -1.7320814206062052 0.0832590667044161
Single stranded telomeric dna binding 5 7 1.730833648883979 0.0834814385135764
Ige binding 1 1 -1.7307539951148694 0.0834956503387518
Nuclear receptor activity 5 6 -1.7253184451313195 0.0844700996385259
Sulfotransferase activity 5 7 -1.7238583584624 0.0847334162937318
Insulin like growth factor i binding 4 4 -1.723118179395286 0.0848671559337916
Macrolide binding 6 7 1.7196528653396368 0.085495560463946
Fk506 binding 6 7 1.7196528653396368 0.085495560463946
Opsonin binding 2 4 1.716324803042398 0.0861026111266389
Potassium channel regulator activity 6 15 -1.7133184635221868 0.0866539674431701
Cysteine type endopeptidase activity involved in apoptotic signaling pathway 2 3 -1.7118179048011457 0.0869302313890629
Protein domain specific binding 98 293 1.711569937626583 0.0869759523560596
Molecular sequestering activity 1 1 -1.7111911404672864 0.0870458336391362
Protein sequestering activity 1 1 -1.7111911404672864 0.0870458336391362
Actin binding 78 172 1.708195747760478 0.0876000272770631
Gpi linked ephrin receptor activity 0 1 1.695473827094322 0.0899855711926438
Chemorepellent activity 0 1 1.695473827094322 0.0899855711926438
Coa transferase activity 0 2 1.69116973476522 0.0908043895843997
Unmethylated cpg binding 3 6 -1.6908957937358828 0.0908567068064365
Calcium dependent phospholipid binding 8 14 1.6900724343531888 0.0910140978149478
Tumor necrosis factor receptor superfamily binding 4 11 -1.688021683352256 0.0914070666605675
Protein tag 2 2 -1.6860386189213374 0.0917883612221965
Phospholipase a2 inhibitor activity 1 3 1.6859968986351928 0.0917963967139186
Rna dna hybrid ribonuclease activity 3 4 1.6832253267465924 0.0923314796963148
Adp ribose diphosphatase activity 1 2 1.6822746540550335 0.0925155936319943
Proton channel activity 9 14 1.6819712008063357 0.0925744245445785
Proton transporting atp synthase activity rotational mechanism 9 14 1.6819712008063357 0.0925744245445785
Mannosyl oligosaccharide 1 2 alpha mannosidase activity 3 3 -1.6789355574112208 0.0931646037571058
Transferase activity transferring phosphorus containing groups 100 366 -1.6786935969608403 0.0932117744951726
S adenosyl l methionine binding 6 8 -1.6782409446829687 0.0933000715458129
Adp binding 11 26 1.676308522031138 0.0936777765273022
Enzyme activator activity 56 197 -1.6700420126861288 0.0949110516479845
Protein antigen binding 0 2 1.667986959983908 0.0953183154168253
Cysteine type endopeptidase activity involved in apoptotic process 4 5 -1.6677775698472288 0.0953598901339198
Cyclase regulator activity 1 1 -1.662724186949371 0.0963676583408021
Oxidoreductase activity acting on peroxide as acceptor 8 15 1.6582925225394307 0.0972584375477105
Acid phosphatase activity 2 5 1.6526540863150625 0.0984012837094463
Acyl carnitine transmembrane transporter activity 1 2 -1.6522781830082347 0.0984778547115201
Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 2 5 -1.6491430054958724 0.0991183409881075
Potassium ion binding 3 7 1.6477814967315858 0.0993975173301948
Protein homodimerization activity 102 275 1.6464324330949471 0.0996747602610694
Tropomyosin binding 1 3 1.645636720409733 0.0998385743123648
Isopeptidase activity 7 12 1.6449365977868229 0.0999828866673435
Pattern recognition receptor activity 1 2 1.6430892448305907 0.1003644697880901
Protein tyrosine phosphatase activity 17 31 -1.6414489446913454 0.1007042569623686
Ubiquitin like protein binding 26 69 -1.6412687937955928 0.1007416309143343
Phosphatidylinositol 3 phosphate binding 9 15 -1.637687953138522 0.1014868049178283
Malate dehydrogenase activity 3 5 1.6337749593311164 0.1023061120788679
Amide transmembrane transporter activity 4 12 -1.632158691525326 0.1026460603454897
N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity 1 2 -1.6201381651506408 0.1052026006768058
Lipid transfer activity 9 17 -1.619956902145585 0.1052415351744737
Ephrin receptor activity 1 2 -1.617695389582606 0.1057282600818165
Acid thiol ligase activity 6 15 1.6160796240983053 0.1060770990217498
Keratin filament binding 1 3 1.614192913057838 0.1064855887238189
Transferase activity transferring one carbon groups 32 117 -1.6132609562854086 0.106687825228475
Minus end directed microtubule motor activity 1 2 1.61088453002752 0.1072048924171451
Transcription regulator inhibitor activity 2 4 1.608230499645105 0.1077847056735823
Cyclin dependent protein serine threonine kinase activator activity 3 5 -1.605117250249692 0.108468003688869
Calcium dependent protein binding 14 29 1.604349670496239 0.1086369982165749
Rna methyltransferase activity 15 42 -1.6042851848852944 0.108651205198889
Isomerase activity 49 101 1.6031349468361895 0.1089048639706335
Oxidoreductase activity acting on ch or ch2 groups 1 3 1.6016279849786856 0.109237898608649
Catalytic activity acting on a trna 29 87 1.5903535527752244 0.1117551336662561
Rna 2 o methyltransferase activity 2 5 -1.5894028206064006 0.1119694782174134
Kinase activator activity 14 33 -1.5881053858712937 0.1122625106420718
Nuclear import signal receptor activity 10 16 1.5878383536634624 0.1123228962382116
Acylglycerol o acyltransferase activity 6 15 -1.5830769195793517 0.1134039335126531
Extracellular matrix structural constituent 3 5 -1.5802780969567358 0.1140431935931016
Phosphatidylinositol binding 43 110 -1.579370217032603 0.1142511645922748
Connexin binding 2 3 -1.5757652091463994 0.1150799230493806
Phosphoric ester hydrolase activity 46 126 -1.5747369098519206 0.1153171844070561
Electron transfer activity 41 77 1.5722843713494858 0.1158846159085134
G rich strand telomeric dna binding 4 6 1.5690261993481696 0.1166418344188606
Promoter specific chromatin binding 16 32 1.5690260800238325 0.1166418622215412
Calcium independent phospholipase a2 activity 1 3 1.5686041521562364 0.1167402043586434
Phospholipase a2 activity 1 3 1.5686041521562364 0.1167402043586434
Hyalurononglucosaminidase activity 1 2 -1.5681317506032335 0.1168503880635323
N acetyltransferase activity 11 32 -1.566897576688096 0.1171386342012783
Oxygen binding 2 4 1.5657646354437231 0.1174037282223083
Histone h3 tri di monomethyl lysine 4 demethylase activity 3 4 -1.5612483353643467 0.1184651684615989
Axon guidance receptor activity 1 2 -1.560213273397374 0.1187094899576943
Calcium activated cation channel activity 1 3 -1.5577806392152995 0.1192852570469158
Hydrolase activity hydrolyzing n glycosyl compounds 3 12 1.5498690927997405 0.1211729392764826
Rna polymerase ii ctd heptapeptide repeat phosphatase activity 3 4 -1.5450008913986708 0.1223460477536153
Tap1 binding 2 4 -1.538746704319954 0.1238661455308993
Myosin v binding 4 10 -1.537445412088557 0.1241842729767068
Gaba receptor binding 2 3 -1.5364491738624422 0.1244282542869088
Phosphatidylethanolamine binding 3 6 1.5362832577439351 0.1244689238682097
Fatty acid derivative binding 8 14 1.5361990377614103 0.1244895719501526
Enzyme inhibitor activity 46 111 1.5353894197765736 0.124688201045009
Fatty acid ligase activity 3 9 1.528061796742575 0.1264971955589784
Carbon oxygen lyase activity 12 31 1.5222379221661273 0.1279494763058277
Spectrin binding 3 8 1.521386416262002 0.1281628956499059
Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor 6 9 1.5204496524862383 0.1283980034200094
Quaternary ammonium group binding 9 17 1.5199787026801732 0.128516328364431
Epoxide hydrolase activity 2 5 1.518552468956329 0.12887518296258
Ether hydrolase activity 2 5 1.518552468956329 0.12887518296258
Catalytic activity acting on a glycoprotein 4 6 -1.5166494247658449 0.1293552196895748
Sodium ion binding 1 2 1.5089879182841917 0.1313018703107709
Rrna adenine methyltransferase activity 2 5 -1.5076630233421284 0.1316407937788204
Organic acid sodium symporter activity 3 3 -1.5060190992659408 0.1320622707710912
Amino acid sodium symporter activity 3 3 -1.5060190992659408 0.1320622707710912
Calcium channel regulator activity 8 12 -1.502576809515991 0.1329482072528467
High density lipoprotein particle binding 2 3 1.5024369886916735 0.1329842897149897
Thyroid hormone receptor binding 5 18 -1.4923522105883953 0.1356068361990769
L aspartate transmembrane transporter activity 2 4 1.4847804464805867 0.1376019932592642
Oxidoreductase activity acting on other nitrogenous compounds as donors 3 6 1.483246518815193 0.138008925864838
Catalytic activity acting on dna 47 138 1.4817856717929443 0.1383973327511292
Type i transforming growth factor beta receptor binding 1 3 1.48096141694272 0.1386168552347921
Glutamate binding 1 2 -1.4807419996066993 0.1386753374865299
Modified amino acid binding 17 30 1.4793625308326217 0.1390434487156642
Receptor tyrosine kinase binding 11 24 1.4698386468604243 0.1416054594249844
Folic acid binding 2 4 1.4690739239203778 0.1418127396012485
Intramembrane lipid transporter activity 2 9 -1.4658551489816565 0.142687752978694
Magnesium ion binding 44 114 1.46415535430487 0.1431515056323462
Lysophospholipid acyltransferase activity 5 13 -1.4633226580109528 0.1433791106445148
Lipopolysaccharide binding 5 8 1.461496271806102 0.1438792979434158
Nucleobase containing compound transmembrane transporter activity 8 20 1.4614676174987116 0.1438871560657348
Rna 7 methylguanosine cap binding 7 10 1.4612386888934004 0.1439499489851154
Poly g binding 3 7 1.4611646394663782 0.143970264528944
Peptide n acetyltransferase activity 9 24 -1.4528798760262245 0.1462571092734508
Y form dna binding 3 4 -1.4507555539682018 0.1468479399752547
Mitogen activated protein kinase p38 binding 2 3 1.450648492490913 0.1468777648775292
Inositol polyphosphate 5 phosphatase activity 2 4 -1.4426935483608871 0.1491068174654544
Phosphotransferase activity nitrogenous group as acceptor 1 4 1.4423778320209997 0.1491958140679656
Channel inhibitor activity 7 14 -1.4409889613520863 0.1495878013726979
Guanyl nucleotide binding 79 186 1.439162773841608 0.1501044098495394
Cyclin dependent protein serine threonine kinase inhibitor activity 3 3 -1.4380166892628727 0.1504293188667238
Atpase coupled ion transmembrane transporter activity 6 9 1.4329401125365815 0.1518749526477263
Pyrophosphate hydrolysis driven proton transmembrane transporter activity 6 9 1.4329401125365815 0.1518749526477263
Acetyl coa hydrolase activity 2 3 1.4289865689366663 0.1530080938249223
Sequence specific single stranded dna binding 4 9 1.428582011551936 0.15312440742272
P type calcium transporter activity 1 4 1.425763590545858 0.1539365939024919
C x3 c chemokine binding 0 2 1.424241847709712 0.1543764747687555
Telomerase rna binding 8 18 1.4240670597527432 0.1544270607384668
Antioxidant activity 15 25 1.422972194591159 0.1547442159019112
Lysophosphatidic acid binding 1 3 1.4182675888198204 0.1561126555232386
Histone methyltransferase binding 5 7 1.4157981682901073 0.1568346060490648
S adenosylmethionine dependent methyltransferase activity 23 88 -1.4130140039246082 0.1576516065772453
D loop dna binding 3 4 -1.4117123229811317 0.158034683421383
Cyclic nucleotide dependent protein kinase activity 2 7 -1.399862152048237 0.1615546016997706
L leucine transmembrane transporter activity 1 2 -1.3960895380905405 0.1626875338557609
Structural constituent of cytoskeleton 27 46 1.3953540965026603 0.1629090864687543
Dna binding bending 4 7 1.3932107446785045 0.1635560715588306
Intronic transcription regulatory region sequence specific dna binding 2 3 -1.3889339165583028 0.1648528458766169
Rna polymerase ii intronic transcription regulatory region sequence specific dna binding 2 3 -1.3889339165583028 0.1648528458766169
Single stranded dna exodeoxyribonuclease activity 3 5 1.3871519549843283 0.1653954322132174
Macromolecule transmembrane transporter activity 11 16 1.3866258146566204 0.1655558924600266
Pyrimidine nucleotide binding 4 6 1.3824685423374878 0.1668278830023872
Dna methyltransferase activity 3 4 -1.381264131851934 0.1671977623696829
Tpr domain binding 3 5 1.3809232382304988 0.1673025639903693
Phospholipid binding 66 170 -1.3758805988606455 0.1688586027043244
Aromatic amino acid transmembrane transporter activity 2 4 -1.3740999359602846 0.169410659337402
Dipeptidyl peptidase activity 3 4 1.372821014939423 0.169807995992048
Calmodulin dependent protein phosphatase activity 2 2 -1.3716530075162936 0.1701714838920147
Signaling receptor inhibitor activity 1 2 1.371451537247984 0.1702342410504147
Structural constituent of postsynaptic actin cytoskeleton 1 2 -1.368008291396481 0.1713094807887012
Cyclosporin a binding 9 14 1.366755718351223 0.1717018868135473
Abc type transporter activity 10 19 -1.365214081968296 0.1721857736531711
Dna topoisomerase activity 2 5 1.3650508898213205 0.1722370558483112
Activin binding 1 2 -1.3611993503107775 0.1734506994458069
Amp binding 4 8 1.3552631826644368 0.1753337207222975
Er retention sequence binding 0 2 1.3529422347951303 0.1760740852775608
Beta galactosidase activity 0 2 1.352421503531855 0.1762405142516521
Guanylyltransferase activity 4 5 -1.3505111765443296 0.1768520710551884
Lrr domain binding 3 6 -1.3487478770628825 0.177417961705554
Phosphatidylcholine transfer activity 1 3 -1.348741125255126 0.1774201311325325
Alkali metal ion binding 3 8 1.3443605654105943 0.1788318192611966
Androgen receptor binding 6 15 1.3427342187337603 0.1793580503320533
Rna adenylyltransferase activity 2 3 -1.340850959575374 0.1799688470739981
Glutamate receptor binding 3 14 -1.3390131871724962 0.1805663799143495
Protein deacetylase activity 4 9 -1.3328013851931686 0.1825969910461693
Kinase regulator activity 23 86 -1.330765311333043 0.1832662452686961
Acyltransferase activity 28 98 -1.328875037482523 0.1838892006553028
Carboxy lyase activity 12 18 1.3247086522604925 0.1852678023271168
Thiamine pyrophosphate binding 3 5 1.3190053824860035 0.1871673130296143
Lysophosphatidic acid phosphatase activity 1 2 1.3158385623025046 0.1882282331989395
Lipoprotein particle receptor activity 3 6 -1.3147459019025989 0.1885953142205734
Nitrite reductase activity 2 4 1.3140321299497268 0.1888353919966412
Hydrolase activity acting on carbon nitrogen but not peptide bonds 17 48 -1.3138581574938029 0.1888939419161508
Protein tyrosine kinase activator activity 0 2 1.3111527144570914 0.1898061741228325
Phosphatidylinositol phosphate kinase activity 3 5 -1.308561174792536 0.1906830396809056
Purine nucleotide transmembrane transporter activity 5 14 1.3085576956064149 0.1906842188890425
Long chain acyl coa dehydrogenase activity 3 4 1.306922627014946 0.1912389905437543
Sterol esterase activity 0 2 1.3027814538818527 0.1926493841783148
Annealing activity 6 12 1.301452103434001 0.1931037489615765
Protein tyrosine kinase binding 9 30 1.2980041909071902 0.1942858948586407
Ubiquitin binding 21 57 -1.2979300295305023 0.1943113799294624
Class i dna apurinic or apyrimidinic site endonuclease activity 1 3 -1.2949144391418663 0.1953497468690037
Protein macromolecule adaptor activity 62 148 1.290523141255578 0.1968690823881071
Nadp binding 13 27 1.2892564333991356 0.1973089515990074
Phosphatase activator activity 4 12 -1.286449968494706 0.1982860690483496
Protein phosphatase regulator activity 11 35 -1.2856891055926931 0.1985515848678369
Ligase activity forming carbon nitrogen bonds 9 31 1.2850085280047403 0.1987893039622936
Tau protein kinase activity 5 13 -1.2820731514578043 0.1998169862664411
Lipid binding 92 260 -1.280261717410023 0.2004531066575827
Ganglioside binding 2 3 1.277518557778332 0.2014192329275066
Coa hydrolase activity 6 11 1.275513149303333 0.2021276729758576
Ubiquitin ligase substrate adaptor activity 5 9 -1.2751087875443672 0.2022707394732363
Histone lysine n methyltransferase activity 6 25 -1.274003314855132 0.2026622413898078
Toxic substance binding 1 3 -1.272770214963036 0.2030995933516388
Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor 6 12 1.272457698047741 0.2032105449555445
3 5 dna helicase activity 7 12 1.2708876600711605 0.2037686170169594
Filamin binding 4 5 -1.2705162659513534 0.2039007925358336
Hormone activity 2 3 -1.2696336550066951 0.2042151554077993
Endoribonuclease activity producing 3 phosphomonoesters 1 2 -1.2689852940773814 0.2044463091218358
Nuclear export signal receptor activity 5 10 1.268756386266424 0.2045279648028333
Nadplus adp ribosyltransferase activity 3 9 -1.2663580715199232 0.2053849149188547
Sequence specific mrna binding 6 9 1.2644738898043435 0.2060599865711121
Volume sensitive anion channel activity 2 6 -1.26072956527784 0.2074062981199826
Histone deacetylase binding 20 51 1.2565399395712926 0.2089202748035603
Transmembrane transporter binding 16 50 1.2562920169950462 0.2090101151887979
Glucose binding 4 7 1.2498734081415248 0.2113457947669197
Ribose phosphate diphosphokinase activity 1 4 1.2491650826127252 0.2116047003008401
Diphosphotransferase activity 1 4 1.2491650826127252 0.2116047003008401
Amino acid transmembrane transporter activity 5 20 -1.2481070631160909 0.2119918520342847
Active transmembrane transporter activity 52 119 1.244719494122513 0.2132348776677597
Vitamin b6 binding 13 28 1.2426391173029332 0.2140008483979474
Organic acid transmembrane transporter activity 7 36 -1.2426250644608772 0.2140060292319496
Protein transporter activity 13 21 1.2366751711489383 0.216207700018153
Translation repressor activity 7 11 1.2354069128037934 0.2166791013474904
Phospholipase a1 activity 0 2 1.2341601948085583 0.217143216754128
Transcription coactivator activity 53 139 1.233690381835355 0.2173182992958551
Chromatin dna binding 33 55 1.2334502566316308 0.2174078245945088
D threo aldose 1 dehydrogenase activity 3 4 1.2298576259400011 0.2187504244530553
Medium chain fatty acid coa ligase activity 0 2 1.229011750523357 0.2190674004093669
Phosphatidylinositol 3 kinase regulator activity 1 3 -1.2288533078933146 0.2191268104733561
Transition metal ion transmembrane transporter activity 5 12 -1.2273007521108297 0.2197095730425802
Histone deacetylase regulator activity 1 3 -1.2272177707621388 0.2197407519514382
Iron ion transmembrane transporter activity 2 2 -1.2257367834552255 0.2202977432854158
Udp xylosyltransferase activity 5 6 -1.2238475300334917 0.2210097503426298
Oxidoreduction driven active transmembrane transporter activity 23 46 1.2232010283735268 0.2212537772733329
Nucleotide transmembrane transporter activity 6 17 1.219934803891402 0.2224895908312201
Protein heterodimerization activity 31 105 1.2161214861826062 0.2239386467577599
Fucosyltransferase activity 2 3 -1.2160781833664749 0.2239551404317672
Trna methyltransferase activity 8 19 -1.2126057878898115 0.225280574960192
Acetylglucosaminyltransferase activity 9 13 -1.212194993117567 0.2254377476363964
Mhc class i protein binding 4 11 1.210095317094151 0.2262423198922383
Arp2 3 complex binding 2 8 -1.207836747852008 0.227110063358086
Gpi anchor binding 2 3 1.2053749370060924 0.2280585923996692
Oxidoreductase activity acting on the ch nh group of donors 7 14 1.2040280267425114 0.2285787461314801
Transferase activity transferring nitrogenous groups 4 12 1.2034059186680612 0.2288192786301897
Rdna binding 1 5 1.2013186907964202 0.2296276028657564
Transition metal ion binding 114 359 -1.1997173868736466 0.2302491181118553
Mitochondrion targeting sequence binding 1 3 1.197997685308161 0.2309179181050731
Laminin binding 4 9 -1.1961849303029128 0.2316244002833354
Nad dependent protein deacetylase activity 3 7 -1.1946490174877888 0.2322241893092438
Gtpase activating protein binding 3 6 1.192273255777521 0.2331541175195866
Nedd8 specific protease activity 2 4 1.1908115028301522 0.2337275921546453
Lipid transporter activity 19 44 -1.190704755588723 0.2337695103503119
Phospholipid transporter activity 10 17 -1.1871990720484804 0.2351491068329887
Mhc class ib protein binding 0 3 1.1830084034354147 0.2368058169910452
Flavin adenine dinucleotide binding 16 44 1.1790870844787102 0.2383635009546103
Protein phosphorylated amino acid binding 7 25 -1.1755016296336078 0.2397940855848483
Aldehyde lyase activity 4 6 1.171565886127779 0.2413713910055737
Protein lipid complex binding 3 8 -1.1709824371239654 0.2416058367332518
Sumo binding 4 9 -1.1670242896153054 0.2432005605567493
Myosin ii binding 1 3 -1.1665518950286573 0.2433913796931386
Nucleoside binding 3 6 1.1651062538891015 0.2439759857191465
Dynein complex binding 5 13 -1.1646695644339513 0.2441527733246749
Core promoter sequence specific dna binding 13 27 -1.162811372648845 0.2449060419426583
Active ion transmembrane transporter activity 27 65 1.1607209384694526 0.2457554039394565
Deacetylase activity 6 14 -1.1583290612419872 0.2467297761765827
Double stranded methylated dna binding 1 3 1.1583206114660909 0.2467332231285541
Pre mrna binding 14 26 1.158198866967962 0.246782890609243
Ubiquitin like protein specific protease activity 20 59 -1.1488137200961348 0.2506328007020684
Damaged dna binding 23 44 1.148289592944672 0.250849033913437
Cation cation antiporter activity 1 3 1.1444269657724573 0.2524466103549583
3 hydroxyacyl coa dehydratase activity 0 2 1.1434565909066414 0.252849067942924
Mannose binding 5 8 1.143320854212159 0.2529053996017767
Atpase coupled inorganic anion transmembrane transporter activity 2 5 -1.143016997074508 0.2530315340895832
Ubiquitin specific protease binding 5 13 1.1426026855825655 0.2532035900146563
Atpase coupled cation transmembrane transporter activity 9 20 1.1412422270120364 0.2537691364063636
O acyltransferase activity 7 23 -1.1357156678942226 0.2560755811529067
Sphingosine n acyltransferase activity 2 5 -1.1343741796980082 0.2566376251032751
G quadruplex dna binding 2 7 1.133752098396247 0.2568985492774525
Vitamin binding 37 71 1.1337207063571786 0.2569117211522629
Protein disulfide isomerase activity 5 12 1.1312176095365098 0.2579635119339378
Glycolipid mannosyltransferase activity 0 3 1.1307060200008263 0.2581788467180734
Oxidoreductase activity acting on the ch ch group of donors 25 41 1.1243279293693762 0.2608739340839316
Mitogen activated protein kinase binding 6 14 -1.1235639308922831 0.2611980649113627
Phosphorus oxygen lyase activity 1 4 -1.1229447872861782 0.2614609444019955
Dioxygenase activity 13 39 -1.1173591501309763 0.2638407939518001
Lys63 specific deubiquitinase activity 3 6 -1.1172000856566693 0.2639087840033782
Phospholipase c activity 3 5 -1.1139846823963595 0.2652857580196603
Carboxypeptidase activity 10 16 1.1138198944517943 0.2653564603799156
Phosphatidylinositol bisphosphate binding 16 36 -1.1105622335923797 0.2667568264495312
Rna polymerase ii c terminal domain phosphoserine binding 1 4 -1.1062369610543377 0.2686239688701914
Phosphoric diester hydrolase activity 9 21 -1.102291163063339 0.2703351099450926
Phosphate ion binding 3 6 1.0989173810480708 0.2718041045735297
Transforming growth factor beta receptor binding 1 5 1.0987989127729816 0.2718557865569662
Protease binding 17 45 1.0965572866144062 0.2728349679702988
G protein coupled receptor binding 16 53 -1.0960807163990378 0.2730434527504013
Protein prenyltransferase activity 7 7 -1.0960333346041349 0.2730641867786421
Titin binding 3 3 -1.0957784903778145 0.2731757237641741
Glutathione oxidoreductase activity 2 4 1.0954522239745297 0.2733185653719499
Protein phosphatase activator activity 3 10 -1.0940640495270555 0.2739268882497905
Primary active transmembrane transporter activity 38 85 1.088701549182753 0.2762855184277253
Palmitoyl coa hydrolase activity 4 8 1.088117559022626 0.276543213012778
Hydro lyase activity 13 24 1.086235285168618 0.2773749100276004
Acyl coa binding 8 15 1.0857956421404034 0.2775694148493564
Low density lipoprotein particle binding 2 5 -1.0843887766116562 0.2781924578822581
Basal transcription machinery binding 19 42 1.083503316349654 0.2785850796467461
Peroxisome targeting sequence binding 2 3 1.0808057326989706 0.2797835378737232
Exonuclease activity 26 57 1.0791863519264198 0.2805046625587661
Mhc protein binding 6 13 1.075530469207718 0.2821372983169365
Prenyltransferase activity 7 15 -1.0722031632549975 0.2836287899300997
Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication 2 5 1.0673326967626944 0.2858216283779367
Manganese ion transmembrane transporter activity 0 4 1.0629050569796346 0.2878250094875731
Sodium channel regulator activity 5 10 -1.0608506143198573 0.2887577959281486
Sodium channel inhibitor activity 4 4 -1.0603184355140465 0.2889997549584628
Peptide hormone receptor binding 1 3 1.058014418311826 0.290048869089563
Ferrous iron binding 4 8 -1.0563045970947496 0.2908290763804537
Phosphatase activity 35 103 -1.0554236949535305 0.2912315906894265
Inorganic anion exchanger activity 2 2 -1.052959343184835 0.2923596261562895
Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines 3 3 -1.0518588126562964 0.2928643310352388
Azole transmembrane transporter activity 1 3 -1.0478652873554088 0.2947006774034695
Polyubiquitin modification dependent protein binding 13 30 -1.0460728840824585 0.2955273834083649
Nuclear receptor binding 22 67 1.045038483594167 0.2960051835861663
Sumo specific protease activity 3 4 -1.043037565002129 0.2969308950707727
Dipeptidase activity 3 5 1.0408800474258388 0.2979312230021225
Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 2 6 1.0312626586625733 0.3024176642645231
Rna polymerase i general transcription initiation factor activity 1 2 -1.0218202692048883 0.3068659741686916
Phosphatase inhibitor activity 5 13 -1.019877289464772 0.307786661565097
Adenylate kinase activity 2 5 1.018361958835349 0.3085059735497331
Cysteine type exopeptidase activity 0 2 1.017649572553286 0.3088445199211671
Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2 6 -1.0147225264756623 0.3102381130063232
Thiolester hydrolase activity 9 24 1.0099102641429665 0.3125382846369071
Cytoskeleton nuclear membrane anchor activity 2 4 1.0094402873380368 0.3127635254045713
Bhlh transcription factor binding 2 6 -1.0058844317611113 0.3144711659896604
Carbohydrate binding 37 70 1.0042732089871926 0.3152469433618352
Methyl cpg binding 8 13 1.0017018712983712 0.3164876026361247
Mutlalpha complex binding 2 5 1.0011664069712765 0.316746364385426
Structural molecule activity conferring elasticity 1 3 -1.001025344442933 0.3168145555787718
Ankyrin repeat binding 3 3 -0.9990054266487126 0.3177920624833414
Phosphatidylserine binding 8 15 0.9958724711720816 0.3193121124659805
Sphingolipid binding 4 10 0.99462645959098 0.3199179736505726
Steroid hormone receptor activity 3 4 -0.9938304632360364 0.320305412542043
General transcription initiation factor binding 10 32 0.9932900852337314 0.3205686078932923
Vinculin binding 4 9 0.993014825280752 0.3207027297388969
Carboxylic ester hydrolase activity 17 51 0.992867598736116 0.3207744816896549
Nadh dehydrogenase activity 17 34 0.9919135413088124 0.3212397028894753
Protein disulfide reductase nad p activity 4 7 0.9904876226625956 0.3219358360036284
N6 methyladenosine containing rna binding 3 7 0.9897509376505104 0.3222958709000507
Ubiquitin like protein conjugating enzyme binding 5 16 0.9870049425082544 0.3236402156266202
Mrf binding 1 2 -0.9855576163611288 0.3243502450144699
Map kinase kinase activity 6 12 -0.9812873247413644 0.3264510715686419
Snare binding 23 47 0.9806296965531274 0.32677538439227
Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 19 43 0.9804566852989648 0.3268607405691686
Steroid dehydrogenase activity 4 10 0.9794406610964635 0.3273622946269658
Ferric iron binding 2 3 -0.9779443263233036 0.3281018602789918
Organophosphate ester transmembrane transporter activity 6 18 0.9774694996884412 0.328336770405651
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 17 55 -0.976417865734342 0.3288574316075849
2 oxoglutarate dependent dioxygenase activity 10 31 -0.9748439857404564 0.3296376547619164
Organic hydroxy compound transmembrane transporter activity 1 4 -0.974759247574668 0.3296796961957238
Rna polymerase ii general transcription initiation factor binding 5 15 0.9732826895913606 0.3304128233737406
Telomerase inhibitor activity 2 2 -0.9704828507605532 0.3318058689674661
Beta 2 microglobulin binding 2 4 -0.9699921413476116 0.3320504093289622
Signaling adaptor activity 9 31 -0.9689222788959247 0.332583968711875
Neurotransmitter transmembrane transporter activity 2 2 -0.9683722710979448 0.3328584827310084
Peptidase activator activity 10 14 0.9675800415575778 0.3332541489203728
Sulfur compound binding 19 72 0.9638032272011008 0.3351445884027293
Dna clamp loader activity 4 8 0.962728344307728 0.3356838685313832
Carbonyl reductase nadph activity 2 5 0.9624465289527928 0.3358253506653343
Insulin like growth factor binding 5 6 -0.9620193567187668 0.3360398807147193
Mitochondrial ribosome binding 3 5 0.9609858047036984 0.3365593053583975
Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 3 7 0.9601884832818768 0.3369603620134753
Alpha catenin binding 2 5 0.9590848885318236 0.3375159824783857
Protein demethylase activity 5 15 -0.9584758554277906 0.3378228608144304
Carbon sulfur lyase activity 5 8 0.9583226085005024 0.3379001067752785
Dttp diphosphatase activity 0 2 0.9568399864325752 0.3386480261137157
Protein adp ribosylase activity 2 5 -0.9560637410965542 0.3390400321295739
Smad binding 10 24 -0.9525755820012516 0.3408051539553016
Molecular carrier activity 26 50 0.9508787901909932 0.341665909801635
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 11 18 0.9503874239714034 0.3419154317070938
Long chain fatty acyl coa binding 1 3 0.94938317720858 0.3424257632766561
Extracellular matrix binding 4 11 -0.946931650681462 0.3436736085518799
Collagen binding involved in cell matrix adhesion 1 2 -0.9447843821890172 0.3447689668243978
Cell matrix adhesion mediator activity 1 2 -0.9447843821890172 0.3447689668243978
Phosphatidylinositol kinase activity 2 8 -0.9409171512183044 0.346747317555534
Catalytic activity acting on a rrna 6 17 -0.9333586390705266 0.3506348281594338
Glucocorticoid receptor binding 2 4 -0.9321760053685192 0.3512455736839692
Phosphatidylcholine binding 5 12 0.9318514912073692 0.3514132797782225
H4 histone acetyltransferase activity 3 7 -0.9298818429504888 0.3524322649749081
Nadph binding 3 11 -0.9265820510669528 0.3541435776319594
O acetyltransferase activity 3 5 -0.9260213709044188 0.3544348741871606
Signaling receptor complex adaptor activity 8 14 -0.924062311869964 0.3554538741253932
Nucleotidyltransferase activity 41 74 0.921296770421114 0.3568955067959605
Rna polymerase binding 18 42 0.9205968889432984 0.3572609270660143
Transcription corepressor activity 26 94 -0.9151243929465872 0.3601263306050462
Glycerophospholipid flippase activity 1 3 -0.910201308072323 0.3627163544450198
Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity 1 3 -0.9089783026468246 0.3633615789987252
Beta 1 3 galactosyltransferase activity 1 3 -0.9089783026468246 0.3633615789987252
Atp dependent dna dna annealing activity 2 5 0.9080455508511563 0.3638541560106292
Magnesium ion transmembrane transporter activity 3 6 -0.9060761402650914 0.3648955531689484
Acetyltransferase activity 15 50 -0.9050369104635846 0.3654458332964201
Cdp alcohol phosphatidyltransferase activity 3 6 -0.9036423231404526 0.3661850915963074
Nad retinol dehydrogenase activity 1 3 -0.8958012547553226 0.370358919633627
Cysteine type peptidase activity 19 84 -0.8956343626093733 0.3704480768441529
Chemokine receptor binding 4 6 0.893201237614023 0.3717494154544394
Cytoskeletal motor activity 16 42 0.8920762860576139 0.3723520445505501
Transcription coregulator binding 11 44 -0.8832745894981875 0.3770879295508678
Phosphoprotein phosphatase activity 22 63 -0.8814874921006622 0.3780540209872349
Bh3 domain binding 0 3 0.8809139137052563 0.3783644160644068
Retinoic acid receptor binding 4 9 0.8807887987184659 0.3784321435643283
Dynein intermediate chain binding 7 11 0.8786866450397568 0.3795712017369452
Clathrin light chain binding 0 3 0.87812449125245 0.3798761633557266
Microfilament motor activity 6 12 0.8776640385999566 0.3801260655223937
Semaphorin receptor activity 2 5 -0.8744708336555674 0.3818618970573477
Beta tubulin binding 14 25 0.8738845745053797 0.3821811160110111
Nucleoside monophosphate kinase activity 8 13 0.8731658327935061 0.3825726951203474
Organic cation transmembrane transporter activity 3 10 -0.8729269162796203 0.3827029141449456
Lamin binding 7 11 0.8726992575267399 0.3828270225123209
Carboxylic acid binding 28 56 0.8722595992627438 0.3830667723942662
R smad binding 5 9 -0.8721432123110359 0.3831302547135959
Exoribonuclease activity 16 35 0.8709802418850705 0.3837649413777548
Chondroitin sulfate binding 1 3 -0.8695969794114553 0.3845206890808788
Glutathione peroxidase activity 6 8 0.8678645879841977 0.3854684668843497
Chloride transmembrane transporter activity 2 2 -0.862206614667179 0.3885738303686405
Voltage gated anion channel activity 6 8 0.8584814644392985 0.3906266612218585
Organic acid binding 26 51 0.8563802714469927 0.3917874735315143
Acyl coa dehydrogenase activity 7 10 0.8507067851434075 0.3949322531153563
Regulatory rna binding 14 24 0.8488774103273723 0.395949509904431
Atpase binding 26 42 0.8456560484720448 0.397744648581849
Transcription coactivator binding 4 13 -0.8454095170055858 0.3978822326921825
Beta 2 adrenergic receptor binding 1 4 -0.8395123438509053 0.4011818652853827
1 phosphatidylinositol binding 4 7 0.8349256919671976 0.4037595481065381
Aminoacylase activity 1 2 -0.832591566386255 0.4050751169987614
Intracellular calcium activated chloride channel activity 1 3 0.832478483316627 0.4051389183290772
Chloride ion binding 2 2 -0.8277489137737245 0.4078127116242265
Glycosphingolipid binding 1 4 0.8276094827250491 0.4078916961868728
Steroid binding 14 33 0.825616354383145 0.40902175487963
Syntaxin binding 15 29 0.8255788729375925 0.4090430238445197
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 3 6 -0.8250639246917499 0.4093352994876345
Voltage gated cation channel activity 1 3 -0.8222840324886819 0.4109152622575045
Voltage gated calcium channel activity 1 3 -0.8222840324886819 0.4109152622575045
Misfolded protein binding 8 19 0.8153694979466114 0.4148608384762999
Chloride channel regulator activity 3 8 -0.8153432266761181 0.4148758719848651
Oxidoreductase activity acting on nad p h 22 48 0.8152223291288349 0.4149450587170937
Mitogen activated protein kinase kinase binding 3 3 -0.8136955062840013 0.415819409137216
Dna replication origin binding 8 17 0.8113933910043022 0.4171397932897727
Demethylase activity 7 20 -0.8081740897043747 0.4189903712366831
K48 linked polyubiquitin modification dependent protein binding 4 6 0.8054005989138012 0.4205885462570771
Tat protein binding 2 6 0.8049017889347887 0.4208763559982249
Phosphatidylinositol 4 5 bisphosphate binding 11 25 -0.8040913261683602 0.4213442335795101
Cyclic nucleotide phosphodiesterase activity 0 2 0.8024155775913028 0.4223126050924106
Retinoic acid binding 2 4 -0.7931304338626314 0.4277018330111117
Transferase activity transferring alkyl or aryl other than methyl groups 36 37 0.7899855128510498 0.4295362289801854
Pyruvate dehydrogenase acetyl transferring kinase activity 1 4 -0.7890699667267916 0.4300711142915276
Dna polymerase binding 6 16 -0.7877133482088978 0.4308643960092573
Histone methyltransferase activity 7 33 -0.7865355112870983 0.4315538232103839
Protein kinase c binding 6 24 0.7815057706178898 0.4345050840563291
Transmembrane receptor protein kinase activity 4 8 -0.7805729930356671 0.4350536810825187
3 5 exonuclease activity 19 41 0.7766504479327501 0.4373650292887598
Gdp binding 24 39 0.7765388574650822 0.4374308868766181
Ceramide binding 3 7 0.772896752645736 0.4395834867375499
Exodeoxyribonuclease activity 6 14 0.7725500533039189 0.4397887135707545
17 beta hydroxysteroid dehydrogenase nadplus activity 2 6 0.7676558836614888 0.4426916522975064
Gtpase inhibitor activity 3 7 0.7663869686520827 0.4434460843189454
Collagen binding 5 17 -0.7635622957685066 0.4451281253912071
Adenylyltransferase activity 5 14 -0.7630828292858921 0.4454139996236235
Phosphotransferase activity for other substituted phosphate groups 6 13 -0.7621071891135489 0.445996032479357
L ornithine transmembrane transporter activity 1 3 -0.7607786047550171 0.4467893156423488
Ubiquinone binding 2 4 -0.7602996594550366 0.4470754853883376
Protein binding involved in heterotypic cell cell adhesion 2 7 0.7592355136838556 0.447711685336678
Estrogen receptor binding 12 19 0.7557253795922791 0.4498138641867433
Cation channel activity 14 33 0.7543880828205177 0.4506162253241488
Phosphatidyl phospholipase b activity 1 3 0.753908195725858 0.4509043489925119
Ubiquitin like protein specific isopeptidase activity 2 3 -0.7530966819358292 0.4513918181651875
Amp activated protein kinase activity 1 5 -0.7520510848073523 0.4520203384601693
L amino acid transmembrane transporter activity 4 15 -0.750434044294908 0.4529933333379714
Pre mirna binding 2 6 0.7490293657168565 0.4538395061278732
Glycosyltransferase activity 36 88 -0.7489054068664424 0.4539142212293399
Profilin binding 3 5 0.7475827163975896 0.454711893003743
Solute anion antiporter activity 3 8 0.7456274409044681 0.4558925016481312
Protein geranylgeranyltransferase activity 5 5 -0.744510167982478 0.4565678920971163
Protein membrane adaptor activity 9 13 0.7404024248308997 0.4590558479282633
Cysteine type endopeptidase activity 16 46 -0.73918702992561 0.459793435504098
Hydroxymethyl formyl and related transferase activity 3 5 0.7391766245058443 0.4597997531115088
Glycosaminoglycan binding 7 26 0.7362399713228941 0.4615846707565527
Calcium dependent protein serine threonine phosphatase activity 2 3 0.7322706515384378 0.4640033887734327
Peptide antigen binding 4 11 -0.731402569013353 0.4645332965610742
Metallochaperone activity 2 6 -0.731313112267233 0.4645879232038441
Endodeoxyribonuclease activity 4 18 0.7310960600552503 0.4647204807028218
Trna cytosine methyltransferase activity 2 4 -0.730234773861962 0.4652466902451002
Deoxyribonuclease activity 10 30 0.7290546924485131 0.4659682077295841
Oxidized dna binding 4 8 0.7286133400105165 0.4662382160749674
Acidic amino acid transmembrane transporter activity 2 5 0.7286110744791771 0.466239602294237
Alcohol binding 6 30 -0.7284508027976716 0.4663376741436416
Dna apurinic or apyrimidinic site endonuclease activity 3 7 -0.7279162560496256 0.4666648514363167
Iron ion binding 7 42 -0.7260476534576776 0.4678095577070353
Phosphatidylethanolamine flippase activity 0 2 0.723405608412542 0.469430726587253
Aspartic type peptidase activity 2 7 0.7183052578662251 0.4725690889422735
Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor 3 8 0.717882315723587 0.4728298526574599
3 5 exodeoxyribonuclease activity 3 8 0.71595193651441 0.474021027346752
Nuclear receptor coactivator activity 14 35 0.7144437224751821 0.4749528440338926
Quaternary ammonium group transmembrane transporter activity 1 3 -0.713219659354828 0.4757098429381217
Calcium channel inhibitor activity 4 4 -0.7129723421150845 0.4758628719581708
Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 18 40 0.7120910186214567 0.4764084155323012
Phosphatidylinositol 3 5 bisphosphate binding 8 13 -0.7099255714085305 0.4777502921000003
Kinase inhibitor activity 9 34 -0.7062998739630174 0.4800016718011901
Exoribonuclease activity producing 5 phosphomonoesters 14 31 0.7056180061211876 0.4804257235444948
Fibroblast growth factor binding 3 7 0.7054602666431042 0.4805238503631113
Phosphatidylinositol phosphate 4 phosphatase activity 1 4 -0.6992186876319342 0.4844153735716188
Chitin binding 1 2 -0.6973917379132023 0.4855576706850826
Transferase activity transferring sulphur containing groups 18 19 -0.6964539576140355 0.4861445819255068
Ribosomal large subunit binding 7 11 0.6949704487897785 0.4870738211871579
Cysteine type endopeptidase inhibitor activity involved in apoptotic process 3 6 0.6944057786829464 0.4874277707877206
Omega peptidase activity 15 49 -0.6867345559078912 0.4922500168737198
5 deoxyribose 5 phosphate lyase activity 1 3 0.6861012312492109 0.4926492745668152
Atpase activator activity 9 18 0.6756382355282939 0.4992703593366221
Signaling receptor regulator activity 7 27 0.6748163377518086 0.4997924591147973
Clathrin binding 15 32 0.6727990826353847 0.5010751214583291
Phosphatidylinositol 4 phosphate binding 4 11 0.6724609626181149 0.5012902840503362
Phosphoserine residue binding 1 8 0.6681405033087799 0.5040439095335656
Diacylglycerol kinase activity 1 2 -0.6678291531595606 0.5042426549994923
Voltage gated channel activity 10 14 0.6669041979246246 0.504833329337169
Phosphotyrosine residue binding 5 16 -0.6630497387020335 0.5072986991840729
Phosphatidylinositol phosphate binding 24 61 -0.6623626128262315 0.5077388583487457
Beta catenin binding 7 29 -0.6606038601884977 0.5088663928232662
Polypeptide n acetylgalactosaminyltransferase activity 1 4 0.6568152396363296 0.5112997239572694
Tbp class protein binding 5 14 -0.6540059825542671 0.5131079512878252
Organic anion transmembrane transporter activity 9 49 -0.6517977415087319 0.5145316588121807
Thiol oxidase activity 2 4 0.6494249519225906 0.516063740289255
Protein serine threonine phosphatase activity 13 33 0.6465065500706837 0.5179513565393599
Arrestin family protein binding 2 3 -0.6446339565825709 0.5191644242487818
Proteasome binding 9 15 0.6421034363910264 0.5208060248497535
Monocarboxylic acid binding 7 26 0.6338247710924783 0.5261951853135303
Carbohydrate derivative transmembrane transporter activity 6 17 0.6312935075400512 0.5278486312570436
P type transmembrane transporter activity 2 8 0.6307038896674518 0.528234155320829
N methyltransferase activity 9 44 -0.6223872900902022 0.5336872358042004
Fatty acid binding 4 16 -0.621521941001191 0.5342562627861533
Quinone binding 5 11 -0.6214178702857671 0.5343247171190117
O methyltransferase activity 5 15 -0.6196898438355356 0.5354620034385065
Gamma tubulin binding 7 15 -0.6189927262231407 0.5359211506857042
Oxidoreductase activity acting on a heme group of donors 4 10 0.6188282449129937 0.5360295130135722
Molecular function activator activity 9 21 0.6154656154836713 0.5382472702361181
Card domain binding 1 2 0.6109597209813097 0.5412262463641819
Aldo keto reductase nadp activity 6 11 0.6044829270570403 0.5455226167259872
Cuprous ion binding 2 3 -0.6041513127256781 0.5457430470589983
Mannosyl oligosaccharide mannosidase activity 4 4 -0.5991457029906907 0.5490757269362225
Insulin receptor binding 8 14 -0.5988670938257682 0.549261516428301
Retinoid x receptor binding 1 4 -0.5986022736069667 0.5494381395507646
Histone acetyltransferase binding 3 10 -0.5980480681852409 0.5498078601375243
Lysophospholipase activity 9 10 0.5963348724834612 0.5509515390703332
Mirna binding 10 21 0.5940355383229674 0.55248834374813
Dna binding transcription factor binding 42 195 -0.5923991412651719 0.5535833412457922
Cytidylyltransferase activity 3 8 -0.592299079730547 0.5536503320430584
Nf kappab binding 3 24 0.5912972377960923 0.554321280023792
Laminin 1 binding 2 3 -0.5909052795513087 0.5545838883346954
1 phosphatidylinositol 4 kinase activity 1 4 -0.5878936104937037 0.556603705463643
Inorganic anion transmembrane transporter activity 5 32 0.5834113136060213 0.5596164434863673
Histone serine kinase activity 0 5 0.5825924943158904 0.5601676593125056
Rna polymerase core enzyme binding 8 30 -0.5807433072083351 0.5614134693126567
G protein activity 3 20 0.5807057468693403 0.5614387878502565
Amino acid binding 10 21 0.5793382984227069 0.5623609284044875
Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 8 24 0.5746846148786137 0.5655046144173539
Rna polymerase activity 14 28 0.5736987596854987 0.5661716677850073
Intraciliary transport particle b binding 1 2 -0.5734041677725316 0.566371069021169
Oligopeptide binding 4 7 0.572164880183807 0.5672102777993264
Microtubule motor activity 24 26 0.5698218669593991 0.5687985227160255
C2h2 zinc finger domain binding 1 5 0.5687006125057193 0.5695593320789569
Calcium ion transmembrane transporter activity 10 21 0.5677052714206937 0.5702351115558526
Very long chain fatty acid coa ligase activity 1 5 0.5672513809178971 0.5705434039924191
Centromeric dna binding 2 5 0.5651389425770929 0.5719792624986029
Protein self association 7 21 0.5595859061894687 0.5757619203418829
Branched chain amino acid transmembrane transporter activity 1 3 -0.5594516448524177 0.5758535235408131
Growth factor receptor binding 9 28 0.5562886670973064 0.5780135332490202
Amino acid cation symporter activity 4 4 -0.5553349975434086 0.578665544916436
Histone deacetylase activity h3 k14 specific 2 4 -0.5524245265714649 0.5806575304988479
Vascular endothelial growth factor receptor 2 binding 1 2 -0.5473743734249417 0.5841215574545671
Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines 4 11 0.5463130170767834 0.5848507899054298
C methyltransferase activity 3 5 -0.5440799660604061 0.5863864460006152
Nucleotidase activity 4 9 0.5425707646723754 0.5874253725156224
D1 dopamine receptor binding 2 4 0.5415602419724274 0.5881214869841105
Nedd8 transferase activity 1 3 -0.5394884188841488 0.5895498859082031
Estradiol 17 beta dehydrogenase activity 2 7 0.5363455582011677 0.591719749798679
Gamma catenin binding 5 6 0.5363430177720893 0.5917215052202598
Peptide lysine n acetyltransferase activity 9 18 -0.5355004413985679 0.5923038524504833
Lipase activator activity 2 5 -0.5353397638615441 0.5924149346856484
Protein serine threonine kinase inhibitor activity 4 15 -0.5350221662839609 0.5926345295699327
Phospholipase binding 2 7 -0.5339972930871304 0.5933434068792427
Bh domain binding 0 4 0.5336350106034401 0.5935940808192037
Small ribosomal subunit rrna binding 2 8 0.5292153270417558 0.5966560854495455
Glutathione transferase activity 6 10 0.5276750272952276 0.5977249088968779
Non membrane spanning protein tyrosine kinase activity 5 11 -0.5226760173556668 0.601199730392056
Retromer complex binding 2 6 0.5217537108038517 0.6018418227117124
Transcription corepressor binding 8 21 0.5153405539608198 0.6063150648984428
Lipase inhibitor activity 2 7 -0.5149827445881661 0.606565077981059
Low density lipoprotein particle receptor binding 6 14 0.5137766214409624 0.6074081748471647
Cyclin binding 10 18 0.5103046917105601 0.6098380163193475
Dna dna annealing activity 2 7 0.5098564139209613 0.6101520595527115
Actin monomer binding 3 9 -0.5084437763641887 0.6111421591284998
Peptide alpha n acetyltransferase activity 3 8 -0.508226702604111 0.6112943664413677
Sphingolipid transfer activity 0 3 0.5074059075541834 0.6118700415017766
Antiporter activity 6 17 0.5061298882141254 0.6127654699943421
Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor 1 3 0.5057602839863974 0.6130249426195222
Glucuronosyltransferase activity 3 4 -0.5045815292283756 0.6138527857266052
Phosphatidylinositol 3 kinase binding 4 8 -0.4981508681370586 0.6183777092286009
Histone h3 methyl lysine 9 demethylase activity 1 5 0.4977260476743985 0.6186771461932064
Tetrapyrrole binding 12 30 -0.4958654201987295 0.6199893648311667
Apolipoprotein binding 2 5 0.4955260234354091 0.6202288571478545
Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides 5 10 -0.4952657651963937 0.6204125333551067
Endoribonuclease activity producing 5 phosphomonoesters 9 22 0.4899079254811658 0.6241990545120188
Sterol transfer activity 2 7 -0.4842210035402335 0.6282290323051298
Sulfurtransferase activity 7 8 0.4826097120114407 0.6293728818980573
Gated channel activity 4 21 0.4816207483355377 0.6300753841953253
Protein c terminus binding 26 96 -0.4811751778720248 0.6303920009425701
Ubiquitin protein transferase activator activity 1 6 0.4799348746881712 0.6312737020897912
Ephrin receptor binding 5 14 -0.4768857784077898 0.6334434595104024
Steroid hormone binding 0 2 0.4766831961523095 0.6335877304311932
Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 4 6 0.4760007693722069 0.6340738297824613
Peroxisome proliferator activated receptor binding 1 3 -0.4755529329104774 0.6343929139639668
Rna polymerase ii core promoter sequence specific dna binding 7 12 -0.4753783096061597 0.6345173517617657
Efflux transmembrane transporter activity 1 5 -0.4741825982691045 0.6353697014798905
Oligosaccharyl transferase activity 2 6 0.473505076939169 0.6358528797509924
Atp dependent chromatin remodeler activity 5 6 0.4714599382943849 0.6373123218462287
Nadh pyrophosphatase activity 0 3 0.4713771759289568 0.637371412002701
Phosphotransferase activity phosphate group as acceptor 6 22 -0.4706979600970897 0.6378564413414938
Camp dependent protein kinase activity 1 6 -0.4700244241736908 0.6383375677984895
Guanylate kinase activity 6 6 -0.4681303783363006 0.63969135624972
Flippase activity 1 4 -0.4674688978568636 0.6401644392531276
Dna secondary structure binding 9 21 -0.4652622358613097 0.6417436750103795
Anaphase promoting complex binding 3 4 0.4632748521202758 0.6431673690762794
Mitogen activated protein kinase kinase kinase binding 2 4 -0.4628605766624337 0.6434643072350106
Ww domain binding 3 7 0.4623694551058038 0.6438163997541972
Ion gated channel activity 1 4 -0.4606782410395007 0.6450294682249855
Kinetochore binding 6 6 -0.4599279394605191 0.6455679450138967
Camp dependent protein kinase inhibitor activity 2 4 -0.4564734254130718 0.6480495762915306
Molybdopterin cofactor binding 2 3 0.4545248452217386 0.6494511137114933
Jun kinase binding 1 3 -0.4528311503375974 0.6506703310828206
Lipid kinase activity 1 3 -0.4503089691887332 0.6524876726199247
Fibronectin binding 1 4 0.4482310800570176 0.653986434365355
Phosphatidylinositol 3 4 5 trisphosphate binding 8 14 0.4481085555954475 0.6540748537518981
2 iron 2 sulfur cluster binding 7 14 0.4475249664616074 0.654496065599286
Solute cation antiporter activity 1 4 0.4463556343313716 0.6553403748359594
Cargo adaptor activity 6 13 0.44592560198244 0.6556509880183565
Floppase activity 2 3 0.4458971845067962 0.6556715161138045
Mismatch repair complex binding 5 8 -0.4445096688609243 0.6566741399303533
Adenylate cyclase binding 2 5 -0.4437170896143498 0.6572471382453058
1 phosphatidylinositol 3 kinase activity 3 3 -0.4394775359309024 0.6603155557304128
Phosphatidylinositol 3 kinase activity 3 3 -0.4394775359309024 0.6603155557304128
Metal ion proton antiporter activity 0 2 0.4378698925958317 0.6614806017478727
Small molecule sensor activity 2 7 0.4371091035359902 0.6620322255128546
Inorganic diphosphatase activity 1 3 0.434387959613822 0.6640067396420322
Aryl hydrocarbon receptor binding 2 3 -0.432389157639795 0.665458597008147
Amyloid beta binding 5 19 0.4307341829404157 0.6666616608905762
Adenyl nucleotide exchange factor activity 7 10 0.4298311190725236 0.6673184942313313
Histone h3 di monomethyl lysine 9 demethylase activity 1 3 -0.429437732645978 0.6676046991847688
Dolichyl diphosphooligosaccharide protein glycotransferase activity 2 5 0.429375890643549 0.6676496962075356
Leucine zipper domain binding 1 4 -0.4292769892622893 0.6677216605861955
Alcohol dehydrogenase nadpplus activity 5 10 0.4281677983916056 0.6685289588882808
Protein carboxyl o methyltransferase activity 2 4 0.4240401777154268 0.6715365122017201
Sirna binding 3 5 0.4235826144847468 0.6718702366591593
I smad binding 0 2 0.4225264622851075 0.6726407897989395
7sk snrna binding 2 7 0.4220847805777231 0.6729631363219626
Immunoglobulin binding 3 3 -0.4217912408554393 0.6731773996518493
Frizzled binding 3 3 -0.4217912408554393 0.6731773996518493
Uridylyltransferase activity 1 4 0.4212929533501992 0.6735411751809917
Nadplus kinase activity 2 5 -0.4212833474077268 0.6735481887640731
Ubiquitination like modification dependent protein binding 3 8 0.4197645655754825 0.6746574530128806
Microtubule plus end binding 6 16 0.4191913878995357 0.675076265585207
Wide pore channel activity 2 7 -0.4191737429968281 0.6750891600557447
Anion channel activity 3 18 0.4182039708732523 0.6757979927718987
Ribonuclease p rna binding 4 7 -0.4153109335518571 0.6779142983119884
Peptidase activator activity involved in apoptotic process 2 5 -0.4147045474949125 0.6783582029513822
Gtp dependent protein binding 5 14 -0.4111414513969417 0.680968816746351
Plus end directed microtubule motor activity 10 11 0.4095265898695667 0.6821532575460074
Metal ion transmembrane transporter activity 16 49 -0.4088321468268924 0.6826628467402935
E box binding 3 6 -0.4071171862147244 0.6839219213251231
Coreceptor activity 1 5 0.4064149190212699 0.6844377595860296
Chloride channel inhibitor activity 3 6 -0.4057490835841038 0.6849269735190799
Long chain fatty acid binding 3 3 -0.405142449554224 0.6853728050702783
Carbon nitrogen ligase activity with glutamine as amido n donor 2 11 0.4003075522853825 0.6889300060694088
Intramolecular transferase activity 9 16 0.3991559257191147 0.689778316376322
Sodium ion transmembrane transporter activity 10 11 0.398253183510631 0.6904435664277166
Dopamine receptor binding 5 8 0.3967265220876268 0.6915691400011541
Lipase activity 8 33 -0.3942732290795624 0.6933793259370553
Vascular endothelial growth factor receptor binding 1 3 0.393123618657087 0.6942281804232293
Lipoprotein particle receptor binding 4 16 0.3915935552010345 0.6953585505710687
Non membrane spanning protein tyrosine phosphatase activity 1 3 0.3874356889984648 0.6984336868742276
Map kinase scaffold activity 2 6 0.3858604043125274 0.6996000566999343
Galactosidase activity 1 4 0.383969096638877 0.7010013524137548
Histone kinase activity 13 14 0.3839414382968194 0.7010218524203526
Protein kinase a catalytic subunit binding 3 9 0.3834178592330782 0.7014099635243716
Atpase coupled intramembrane lipid transporter activity 4 5 -0.379531642414204 0.7042931115486233
Hydrolase activity hydrolyzing o glycosyl compounds 8 35 -0.3786599296550105 0.7049404127864216
Ligand gated ion channel activity 0 3 0.3776061502354293 0.7057231951752603
Hormone receptor binding 2 5 -0.377342971266892 0.7059187419117843
Insulin receptor substrate binding 1 4 -0.3759238755064258 0.7069734901354743
Minor groove of adenine thymine rich dna binding 3 5 0.371070723557341 0.7105848560367063
Interleukin 6 receptor binding 1 2 0.3678349991945958 0.7129962702344617
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 2 4 -0.3674229858807204 0.713303528536092
Oxidoreductase activity acting on the ch nh2 group of donors 1 4 -0.3650217611680038 0.7150951623165047
Glycolipid binding 9 14 0.3629178996892054 0.7166662150479908
Phosphatidylglycerol binding 1 5 0.3627076588460508 0.7168232778652226
Armadillo repeat domain binding 5 6 0.3570923070235859 0.7210227034427095
Leucine binding 2 3 -0.3540141052194875 0.723328312461446
Serine type endopeptidase inhibitor activity 3 9 0.3528951707406383 0.7241670314082709
Insulin binding 2 3 -0.3508762664530954 0.725681177510862
Phosphatidylcholine transporter activity 1 4 -0.3507289814732382 0.7257916809622336
Pre mrna intronic binding 3 8 0.3493721036940126 0.7268099734559321
Bubble dna binding 3 5 -0.3462443966228761 0.729159052066308
Cyclic nucleotide binding 3 8 -0.3448193241792838 0.7302302044784548
Histone h3 methyl lysine 36 demethylase activity 5 5 -0.3408994810590042 0.7331792554973284
Ammonium transmembrane transporter activity 2 2 -0.340768301387566 0.7332780155005618
Syntaxin 1 binding 2 6 -0.3400759607901507 0.7337993245460206
Ccr chemokine receptor binding 2 4 0.3386289640581161 0.7348892602556265
Intramolecular transferase activity phosphotransferases 3 6 0.3366069744328142 0.7364131978982575
Histone methyltransferase activity h3 k4 specific 2 9 -0.3362284599866261 0.7366985929711216
Aspartic endopeptidase activity intramembrane cleaving 1 4 0.3336270937173491 0.7386609707380343
Proline rich region binding 3 10 -0.3332032747049728 0.7389808463810448
Cardiolipin binding 1 4 0.3331323733286266 0.7390343633132441
Notch binding 5 6 0.3329705162133229 0.7391565391089159
5 3 dna helicase activity 2 7 0.3316356682062763 0.7401643830544604
Solute sodium symporter activity 6 6 -0.3315612883022756 0.7402205549004084
Dna insertion or deletion binding 3 6 0.331473590724924 0.7402867860583142
Neurexin family protein binding 3 3 -0.329342941138369 0.7418964904768908
Vitamin transmembrane transporter activity 4 10 0.3258086972613519 0.7445690980216939
Enzyme regulator activity 108 406 -0.3257292770211089 0.7446291913713812
Phosphatidylinositol 5 phosphate binding 4 5 0.3209468148911637 0.7482506958880955
Hexosaminidase activity 2 7 -0.3208419449157463 0.7483301709510441
Modification dependent protein binding 26 100 -0.3198451656055997 0.7490857073846544
Antigen binding 4 13 -0.3163571502346216 0.7517314371506991
Nitric oxide synthase regulator activity 1 6 0.3147296408435635 0.7529669369649006
Solute proton symporter activity 1 5 -0.313782253845269 0.7536864235491807
Growth factor activity 2 9 0.3136961691867908 0.7537518105656364
Diacylglycerol binding 3 3 -0.3136714511229695 0.7537705859033725
Single stranded dna endodeoxyribonuclease activity 5 6 0.3110709470687673 0.7557466870850165
Structural constituent of postsynapse 2 8 -0.310881508502539 0.7558907024970809
Cholesterol binding 4 22 -0.3077416587927608 0.7582789178759892
Dynactin binding 5 8 0.3071389006259577 0.7587376493142812
Potassium ion transmembrane transporter activity 7 8 0.304104152752999 0.7610485431430967
Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity 1 4 -0.3032756484767604 0.7616798025243057
Phosphatidylinositol trisphosphate phosphatase activity 1 4 -0.3032756484767604 0.7616798025243057
1 alkyl 2 acetylglycerophosphocholine esterase activity 1 3 -0.3003702184673071 0.763894777685086
Protein tyrosine serine threonine phosphatase activity 3 10 -0.2990294346525043 0.7649175868914506
Long chain fatty acid transporter activity 2 8 -0.2953590397426996 0.7677196197913589
Dynein light chain binding 4 4 -0.2923582968555397 0.7700126902547066
Transmembrane receptor protein tyrosine kinase activity 3 7 -0.286236649018213 0.774696875612146
Sphingolipid transporter activity 1 4 0.2838802767139848 0.7765021318619265
Fatty acid synthase activity 2 4 -0.2794654910981773 0.7798876175132539
Procollagen proline dioxygenase activity 2 6 0.2778244883129782 0.7811470919724557
Mismatched dna binding 3 8 -0.2775667202782226 0.7813449819705005
Dna translocase activity 3 3 -0.2773466743452945 0.7815139236978108
Acid amino acid ligase activity 1 8 0.2756887115797101 0.7827871666141901
Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 2 4 -0.2755201948041516 0.7829166127742166
L glutamine transmembrane transporter activity 2 3 0.2751461701627816 0.7832039412690539
Nucleoside kinase activity 2 6 0.2742672094336499 0.78387928173305
Rrna cytosine methyltransferase activity 2 4 -0.2708807566336475 0.7864827458705255
Metallocarboxypeptidase activity 3 7 -0.2701394540437231 0.7870529700968576
G protein coupled serotonin receptor binding 3 4 0.2695795944591216 0.7874837005795559
Roundabout binding 1 2 -0.2682138056085297 0.788534748863545
Ubiquitin ubiquitin ligase activity 3 9 0.2674262964680182 0.7891409548325268
Death domain binding 1 5 -0.2666629245647907 0.7897287023993833
Insulin like growth factor receptor binding 2 5 -0.2643126682714892 0.7915389994199733
Rna polymerase ii c terminal domain binding 0 7 0.263542509726146 0.7921324631706292
Protein methyltransferase activity 9 45 -0.2624020389203105 0.7930115009107765
G protein beta gamma subunit complex binding 4 8 0.2597327223661674 0.7950699498344123
Sterol transporter activity 15 15 -0.258913802987398 0.7957017479996851
Nucleotide diphosphatase activity 3 7 -0.2524943316352371 0.8006589949086103
Phosphatidylinositol transfer activity 2 4 -0.2511845916798332 0.8016713968156521
Hormone binding 7 14 -0.2499788911733011 0.8026036728977597
Clathrin heavy chain binding 0 7 0.2486532589259661 0.8036290073348662
Adenosine deaminase activity 1 4 -0.2478491159589845 0.8042511512053607
Oxidative rna demethylase activity 1 4 -0.24750884566046 0.8045144465805332
Rna polymerase iii transcription regulatory region sequence specific dna binding 1 4 -0.2474842593638966 0.80453347189843
Oxidoreductase activity acting on nad p h heme protein as acceptor 1 5 -0.2458557956176503 0.8057938636363888
Translation activator activity 3 5 0.244017763377909 0.8072170625108295
Monocarboxylic acid transmembrane transporter activity 1 8 -0.2439287175454361 0.8072860274594693
Dystroglycan binding 1 7 0.2375697322446763 0.8122148286202255
Arylsulfatase activity 0 3 0.2346852424033008 0.8144530427352117
Exogenous protein binding 8 27 -0.2309983895397576 0.8173160531610608
Hexosyltransferase activity 22 62 -0.2293280168386924 0.8186139793650369
Phosphatidic acid binding 4 8 -0.2292857350543167 0.8186468399590487
Molecular function inhibitor activity 6 19 -0.2235568640872996 0.8231021315883895
Phosphatidylinositol 3 kinase regulatory subunit binding 0 3 0.2222428361711498 0.8241248493667166
Fmn binding 1 6 -0.2221445505891152 0.8242013577998337
Potassium chloride symporter activity 3 3 -0.2209941093347562 0.8250970196641143
Cation chloride symporter activity 3 3 -0.2209941093347562 0.8250970196641143
Cytokine receptor binding 8 36 -0.2195654206737991 0.8262096245190458
Hydrolase activity acting on glycosyl bonds 10 47 -0.2182200723563188 0.8272576464476764
Pseudouridine synthase activity 3 8 -0.2179219771253247 0.8274899033648273
Solute proton antiporter activity 1 3 0.2153638424609136 0.8294836580918867
Lim domain binding 2 4 -0.2145283299737694 0.8301350770546891
Modified amino acid transmembrane transporter activity 1 7 -0.2082888820050569 0.8350034121559191
Four way junction helicase activity 3 5 -0.2080323430627032 0.8352037136495385
Lys48 specific deubiquitinase activity 3 9 -0.2046070613735075 0.8378791379450106
Voltage gated chloride channel activity 4 4 -0.204011539855023 0.8383444810582081
Protein tyrosine kinase inhibitor activity 1 4 -0.1977661697060866 0.8432280160189405
Nucleotide phosphatase activity acting on free nucleotides 0 4 0.1974371635063422 0.8434854496719
Peptide hormone binding 1 4 0.1968954703523056 0.843909338431764
Microtubule minus end binding 4 11 -0.1897875137727732 0.8494756406355812
Sulfur compound transmembrane transporter activity 4 13 -0.1888465033619867 0.8502131231288375
Chemokine binding 2 5 -0.1818921202313358 0.8556673884899917
Acyl coa oxidase activity 2 4 0.1807545920623212 0.8565602062018289
Histone methyltransferase activity h3 k36 specific 3 6 -0.1780635287179231 0.858673084120519
Adrenergic receptor binding 2 8 -0.1755804067924808 0.8606235963185469
Myristoyltransferase activity 2 6 -0.1753451322903894 0.8608084506245759
G quadruplex rna binding 3 4 0.1724213069395046 0.8631063225055766
Growth factor binding 8 25 -0.1718496768765238 0.8635557099224251
Mrna methyltransferase activity 2 10 -0.1677828835648739 0.8667540885368048
Thioredoxin disulfide reductase activity 3 3 -0.1640078114996816 0.869724994395886
Poly a specific ribonuclease activity 3 10 -0.1627373189539383 0.8707252623727224
Protein kinase a regulatory subunit binding 4 15 -0.1613017304637703 0.8718557603950627
Pre mrna 3 splice site binding 2 3 0.1608956896488519 0.8721755572376859
Thioesterase binding 1 5 -0.1492815207561921 0.881331496179846
Camp binding 2 5 -0.1488129936196821 0.8817011973821662
Nucleoside diphosphatase activity 3 5 -0.1484682581538662 0.8819732346257454
Camp dependent protein kinase regulator activity 2 5 -0.1442973152207886 0.8852656982654104
Trna specific ribonuclease activity 5 10 -0.1389822189017205 0.8894641999329644
Integrin binding 16 34 -0.1373437886919823 0.8907590599884929
Serine transmembrane transporter activity 1 5 -0.1364244349432818 0.8914857579692059
Cullin family protein binding 3 10 -0.1338756706860234 0.8935008890583931
Anion transmembrane transporter activity 12 76 -0.1280862515646485 0.8980807160871285
Lipase binding 1 3 -0.1263652114533302 0.8994428386028659
Copper ion binding 7 18 -0.1239530486972555 0.9013524499898112
Sulfate binding 1 4 -0.1208513066045475 0.9038088110844572
Protein phosphatase 1 binding 4 8 -0.1202371063899335 0.9042953243343708
Anion cation symporter activity 4 4 -0.1199452111657268 0.9045265496476518
Fad binding 7 17 -0.1156568173511618 0.9079245312632652
S acyltransferase activity 4 9 -0.1106331130886601 0.9119072882119276
Protein kinase b binding 4 5 -0.1075420320338206 0.9143589819083866
Neutral amino acid transmembrane transporter activity 2 9 -0.1069973748587253 0.9147910623596632
1 acylglycerophosphocholine o acyltransferase activity 2 5 -0.1022616163325945 0.9185490212693348
Primary mirna binding 1 5 -0.1017242935167597 0.9189755187307248
Acylglycerol lipase activity 4 4 -0.099904422257752 0.9204202054649828
Ligase activity forming phosphoric ester bonds 2 6 -0.0988398559396866 0.9212654229489454
Ubiquitin like protein conjugating enzyme activity 5 15 -0.0950144847079417 0.9243033218387848
Phospholipase inhibitor activity 1 5 -0.0897298727353557 0.9285018766775373
Mannosyltransferase activity 3 10 -0.0792252777706917 0.9368534390276948
Nadplus binding 2 10 -0.0750544843667709 0.9401713618416376
Palmitoyl protein hydrolase activity 2 10 -0.0747353330540111 0.9404252945602188
Sulfatide binding 1 5 -0.0730478726737932 0.9417680223515396
Cyclin dependent protein kinase activity 3 13 -0.068024353516001 0.9457662478808496
Structural constituent of muscle 5 11 -0.0677428164292217 0.945990364993466
Neurotrophin receptor binding 1 3 -0.0644624660074365 0.9486019927121778
Neurotrophin trk receptor binding 1 3 -0.0644624660074365 0.9486019927121778
Dna directed dna polymerase activity 3 13 -0.0644232810758966 0.9486331929113564
Polysaccharide binding 2 2 -0.0616369916773133 0.9508519178348692
Sh2 domain binding 9 18 -0.0609366346911366 0.9514096733801852
Cobalamin binding 6 6 -0.0596919085053338 0.9524010163221934
Nucleobase containing compound kinase activity 8 30 -0.0574274509228168 0.954204696405904
Histone methyltransferase activity h4 k20 specific 1 3 -0.0462220585536479 0.9631332610790888
Cytokine binding 4 12 -0.039471944091017 0.9685141214506188
Ribonuclease p activity 4 8 -0.0390140735098561 0.9688791681182968
Procollagen proline 4 dioxygenase activity 1 4 -0.0296103925278539 0.9763777769102792
Cysteine type endopeptidase regulator activity involved in apoptotic process 3 10 -0.0263049740648148 0.9790140875554312
Histone h3 methyl lysine 4 demethylase activity 2 7 -0.0245671996684246 0.980400182271742
Transferrin receptor binding 3 7 -0.0197760194087712 0.9842220478820036
Carbon nitrogen lyase activity 2 7 -0.0190045292297653 0.9848374922602764
Galactosyltransferase activity 4 8 -0.0187576535110321 0.9850344354763656
2 acylglycerol 3 phosphate o acyltransferase activity 2 6 -0.0179006906325612 0.9857180780579328
Sulfuric ester hydrolase activity 2 5 -0.0162568332134857 0.9870294950914356
Cytoskeletal anchor activity 4 11 -0.0151982480813237 0.987874019329924
Phosphoprotein binding 13 46 -0.0147848502669481 0.9882038259975984
Deoxynucleoside kinase activity 2 4 -0.0130071641983714 0.9896220771408806
Palmitoyltransferase activity 4 9 -0.0121632609674652 0.990295361157632
Calcium dependent cysteine type endopeptidase activity 2 5 -0.0076362804752164 0.9939071889217136
Deaminase activity 2 10 -0.0069815060601832 0.9944296093549296
Tau protein binding 7 29 -0.0054718401293165 0.9956341250281164
Co smad binding 1 3 0.0 1.0
Intermediate filament binding 2 6 0.0 1.0
Protein kinase a binding 7 28 0.0 1.0
Nitric oxide synthase binding 1 5 0.0 1.0
M7g 5 pppn diphosphatase activity 1 8 0.0 1.0
Cation transmembrane transporter activity 17 120 0.0 1.0
Inorganic molecular entity transmembrane transporter activity 28 127 0.0 1.0
Gdp dissociation inhibitor activity 5 10 0.0 1.0
Kinesin binding 3 19 0.0 1.0
Kinase binding 74 298 0.0 1.0
Phosphatase binding 16 82 0.0 1.0
Lysine acetylated histone binding 18 18 0.0 1.0
Protein phosphatase binding 14 68 0.0 1.0
Signaling receptor binding 62 295 0.0 1.0
Dihydropyrimidinase activity 2 5 0.0 1.0
Epidermal growth factor receptor binding 3 11 0.0 1.0
Scavenger receptor activity 1 7 0.0 1.0
Gtpase binding 37 158 0.0 1.0
Muscle alpha actinin binding 6 6 0.0 1.0
Tubulin binding 47 173 0.0 1.0
Endonuclease activity 17 61 0.0 1.0
Rna polymerase ii specific dna binding transcription factor binding 28 149 0.0 1.0
Pentosyltransferase activity 10 26 0.0 1.0
Hydrolase activity acting on ester bonds 94 298 0.0 1.0
Endoribonuclease activity 11 36 0.0 1.0
Atpase regulator activity 4 12 0.0 1.0
Molecular adaptor activity 49 189 0.0 1.0
Amidine lyase activity 5 5 0.0 1.0
Four way junction dna binding 4 11 0.0 1.0
Ribonuclease activity 12 73 0.0 1.0
Nucleoside diphosphate kinase activity 3 10 0.0 1.0
Phospholipase activity 9 26 0.0 1.0
Nadp retinol dehydrogenase activity 1 8 0.0 1.0
Trna guanine methyltransferase activity 10 11 0.0 1.0
Dynein light intermediate chain binding 8 9 0.0 1.0
Carnitine o acyltransferase activity 1 4 0.0 1.0
Protein phosphatase 2a binding 2 17 0.0 1.0
Alpha actinin binding 7 7 0.0 1.0
Copper chaperone activity 1 5 0.0 1.0
Protein carrier chaperone 15 17 0.0 1.0
Passive transmembrane transporter activity 9 57 0.0 1.0
Symporter activity 16 16 0.0 1.0
Scaffold protein binding 4 34 0.0 1.0
Chemoattractant activity 2 6 0.0 1.0
Ccr5 chemokine receptor binding 3 3 0.0 1.0
Cytoskeletal protein binding 98 418 0.0 1.0
Transcription factor binding 50 256 0.0 1.0
Cargo receptor activity 3 15 0.0 1.0
S methyltransferase activity 5 5 0.0 1.0
Heparin binding 3 19 0.0 1.0
Transcription coregulator activity 52 242 0.0 1.0
Sterol binding 4 26 0.0 1.0
Membrane insertase activity 12 13 0.0 1.0
Udp glucosyltransferase activity 9 9 0.0 1.0
Histone threonine kinase activity 6 7 0.0 1.0
Molecular function regulator 141 510 0.0 1.0
Dna polymerase activity 3 16 0.0 1.0
G protein alpha subunit binding 3 7 0.0 1.0
Methylated histone binding 11 47 0.0 1.0
Acetylgalactosaminyltransferase activity 6 6 0.0 1.0
P53 binding 6 35 0.0 1.0
Monooxygenase activity 4 13 0.0 1.0
Structural constituent of synapse 2 11 0.0 1.0
Histone binding 34 143 0.0 1.0
Gtpase activity 25 145 0.0 1.0
Microtubule binding 34 128 0.0 1.0
Ubiquitin conjugating enzyme binding 2 12 0.0 1.0
Rna polymerase ii ctd heptapeptide repeat kinase activity 1 11 0.0 1.0
Secondary active transmembrane transporter activity 10 36 0.0 1.0
Tumor necrosis factor receptor binding 1 6 0.0 1.0
Tap binding 7 7 0.0 1.0
Rna polymerase i transcription regulatory region sequence specific dna binding 1 6 0.0 1.0
Heme transmembrane transporter activity 2 4 0.0 1.0
Manganese ion binding 4 36 0.0 1.0
Pdz domain binding 20 24 0.0 1.0
Transporter activity 41 296 0.0 1.0
Glucosyltransferase activity 3 15 0.0 1.0
Solute cation symporter activity 13 14 0.0 1.0
Dynein heavy chain binding 1 5 0.0 1.0
Snap receptor activity 23 24 0.0 1.0
Calcium ion binding 36 139 0.0 1.0
Calmodulin binding 23 69 0.0 1.0
Vitamin d receptor binding 2 11 0.0 1.0
Actinin binding 10 10 0.0 1.0
Ion transmembrane transporter activity 25 170 0.0 1.0
L ascorbic acid binding 4 13 0.0 1.0
Atpase coupled transmembrane transporter activity 11 39 0.0 1.0
Peptidyl proline dioxygenase activity 3 8 0.0 1.0
Peptidyl proline 4 dioxygenase activity 2 5 0.0 1.0
17 beta hydroxysteroid dehydrogenase nadpplus activity 2 4 0.0 1.0
Nuclease activity 28 113 0.0 1.0