| term overlap setsize score pval |
| Neutrophil degranulation 22 319 3.1921296296296298 8.952514544510764e-06 |
| Innate immune system 34 624 2.5442916533418614 6.248947086397488e-06 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 8 56 6.934173669467787 5.349429381762548e-05 |
| Transport of small molecules 22 377 2.6545523138833 0.0001137602599923 |
| Abc transporter disorders 8 61 6.276835262406849 9.996092046331004e-05 |
| Hedgehog ligand biogenesis 7 53 6.3059850827724215 0.0002613122391266 |
| Metabolism of lipids 26 508 2.321463598642022 0.0002302016690116 |
| Cristae formation 5 27 9.36250471520181 0.0004102788019959 |
| Disorders of transmembrane transporters 10 115 3.972962066182405 0.0004506920536562 |
| Keratan sulfate keratin metabolism 4 17 12.63445645263827 0.0006143549700213 |
| Antigen processing cross presentation 8 77 4.813542808427719 0.0005127634872309 |
| Cross presentation of soluble exogenous antigens endosomes 6 41 7.082142857142857 0.0004109523281683 |
| Uch proteinases 8 79 4.677003195644455 0.0006100016710547 |
| Peptide ligand binding receptors 4 17 12.63445645263827 0.0006143549700213 |
| Sphingolipid metabolism 7 62 5.2693039178394825 0.0006936045596716 |
| Unblocking of nmda receptors glutamate binding and activation 3 9 20.46090534979424 0.0010464818333657 |
| Metabolism of polyamines 6 48 5.897619047619048 0.0009743779436676 |
| Auf1 hnrnp d0 binds and destabilizes mrna 6 48 5.897619047619048 0.0009743779436676 |
| Glycosphingolipid metabolism 5 33 7.35180794309425 0.0010720436073174 |
| Degradation of axin 6 48 5.897619047619048 0.0009743779436676 |
| Negative regulation of notch4 signaling 6 49 5.759883720930232 0.0010882828125207 |
| Degradation of dvl 6 50 5.6284090909090905 0.001212131153867 |
| Asymmetric localization of pcp proteins 6 54 5.157291666666667 0.0018183768983854 |
| Regulation of runx3 expression and activity 6 52 5.3826086956521735 0.0014919193154812 |
| Class a 1 rhodopsin like receptors 4 21 9.657754010695188 0.0014320459890063 |
| Defective cftr causes cystic fibrosis 6 54 5.157291666666667 0.0018183768983854 |
| Trans golgi network vesicle budding 7 69 4.671075718720475 0.0013192316861744 |
| Scf skp2 mediated degradation of p27 p21 6 54 5.157291666666667 0.0018183768983854 |
| Dectin 1 mediated noncanonical nf kb signaling 6 53 5.267553191489362 0.0016490180911792 |
| Cdt1 association with the cdc6 orc origin complex 6 54 5.157291666666667 0.0018183768983854 |
| Degradation of gli1 by the proteasome 6 53 5.267553191489362 0.0016490180911792 |
| Stabilization of p53 6 51 5.502777777777778 0.0013464853239791 |
| Signaling by notch4 7 71 4.524189330543933 0.0015612560180347 |
| Long term potentiation 3 11 15.342592592592592 0.001983278822638 |
| Keratan sulfate biosynthesis 3 11 15.342592592592592 0.001983278822638 |
| Abc family proteins mediated transport 7 75 4.256337681516121 0.0021480935661603 |
| Regulation of ras by gaps 6 57 4.852450980392157 0.0024061053673092 |
| Regulation of hmox1 expression and activity 6 58 4.758653846153846 0.0026306375243077 |
| Tnfr2 non canonical nf kb pathway 6 58 4.758653846153846 0.0026306375243077 |
| Cellular response to hypoxia 6 59 4.668396226415094 0.0028705350867404 |
| Regulation of mrna stability by proteins that bind au rich elements 7 79 4.018247326824732 0.0028924350901622 |
| G1 s dna damage checkpoints 6 61 4.497727272727273 0.0033989983353886 |
| Regulation of runx2 expression and activity 6 61 4.497727272727273 0.0033989983353886 |
| Ras activation upon ca2 influx through nmda receptor 3 13 12.271604938271604 0.0033170374819039 |
| Interleukin 1 signaling 7 82 3.856345885634589 0.0035695402472551 |
| Ub specific processing proteases 10 151 2.9477701646832557 0.0035640191312987 |
| Signaling by notch 10 152 2.926712819288613 0.0037362493733334 |
| Separation of sister chromatids 11 179 2.72548125633232 0.0040543858610966 |
| Formation of atp by chemiosmotic coupling 3 14 11.154882154882156 0.0041470760753771 |
| Negative regulation of nmda receptor mediated neuronal transmission 3 14 11.154882154882156 0.0041470760753771 |
| Regulation of pten stability and activity 6 63 4.3390350877192985 0.0039966852967412 |
| Clec7a dectin 1 signaling 7 85 3.706898401459071 0.0043610876134259 |
| Glycerophospholipid biosynthesis 7 86 3.659604893808591 0.004652372899716 |
| Transcriptional regulation by runx3 7 86 3.659604893808591 0.004652372899716 |
| Orc1 removal from chromatin 6 65 4.191101694915254 0.0046688430045599 |
| N glycan antennae elongation in the medial trans golgi 3 15 10.224279835390949 0.0050923434600555 |
| The role of gtse1 in g2 m progression after g2 checkpoint 6 67 4.052868852459016 0.0054207505619159 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 6 68 3.987096774193549 0.0058282629537454 |
| Fceri mediated nf kb activation 6 68 3.987096774193549 0.0058282629537454 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 6 68 3.987096774193549 0.0058282629537454 |
| Striated muscle contraction 3 16 9.43684710351377 0.0061570039439817 |
| Signaling by the b cell receptor bcr 7 91 3.4400278940027893 0.0063342661912929 |
| Hedgehog on state 6 70 3.86171875 0.0067097031977977 |
| Protein localization 9 142 2.802988483867898 0.0074043156533507 |
| Downstream signaling events of b cell receptor bcr 6 71 3.8019230769230767 0.0071849444758907 |
| Deubiquitination 12 221 2.390136179609864 0.0073038252297149 |
| Interleukin 1 family signaling 7 95 3.2823316850513504 0.007976907507528 |
| C type lectin receptors clrs 7 100 3.1042875781706933 0.0104482115740687 |
| Golgi associated vesicle biogenesis 5 55 4.1078838174273855 0.0102355224712358 |
| Degradation of beta catenin by the destruction complex 6 77 3.478521126760564 0.0105604779584046 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 3 19 7.665123456790123 0.0101015401572799 |
| Mapk6 mapk4 signaling 6 77 3.478521126760564 0.0105604779584046 |
| Pcp ce pathway 6 78 3.4298611111111112 0.0112163349420639 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 3 20 7.213507625272332 0.0116756742779249 |
| Cyclin a cdk2 associated events at s phase entry 6 79 3.3825342465753425 0.011900491094562 |
| Class i mhc mediated antigen processing presentation 14 295 2.0764204196833966 0.0122151518034908 |
| Apc c mediated degradation of cell cycle proteins 6 81 3.2916666666666665 0.0133560961650828 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 3 21 6.812071330589849 0.0133829456596615 |
| Mitochondrial calcium ion transport 3 21 6.812071330589849 0.0133829456596615 |
| Mapk family signaling cascades 11 212 2.270329205038637 0.0137442329123423 |
| Mitotic g2 g2 m phases 10 186 2.3531394453004624 0.0146804600150792 |
| Synthesis of pg 2 8 13.584699453551911 0.0147480216610697 |
| N glycan antennae elongation 2 8 13.584699453551911 0.0147480216610697 |
| Muscle contraction 6 83 3.2055194805194804 0.0149319876934548 |
| Cellular response to chemical stress 8 133 2.642016806722689 0.0151431280877408 |
| Fc epsilon receptor fceri signaling 7 108 2.856083516301421 0.0154968415322929 |
| The citric acid tca cycle and respiratory electron transport 9 160 2.464330622851873 0.0154167515498282 |
| G2 m checkpoints 8 134 2.62078164599173 0.0157806738818379 |
| Tcr signaling 6 85 3.12373417721519 0.0166326939811153 |
| Switching of origins to a post replicative state 6 85 3.12373417721519 0.0166326939811153 |
| Cytoprotection by hmox1 7 110 2.800056871267823 0.0169905591315889 |
| Mucopolysaccharidoses 2 9 11.642857142857142 0.0186627473263165 |
| Cholesterol biosynthesis 3 24 5.837154614932393 0.0193169154759243 |
| Antigen presentation folding assembly and peptide loading of class i mhc 3 24 5.837154614932393 0.0193169154759243 |
| Mitotic metaphase and anaphase 11 225 2.1295685026844304 0.0204959415593279 |
| Host interactions of hiv factors 7 116 2.644313078192776 0.0220782152653952 |
| Endosomal vacuolar pathway 2 10 10.186475409836063 0.0229613270793894 |
| Fatty acid metabolism 7 117 2.6200076074553063 0.0230184986659368 |
| Defects in cobalamin b12 metabolism 2 10 10.186475409836063 0.0229613270793894 |
| Synthesis of pa 3 25 5.5712682379349046 0.0215683584236732 |
| Sting mediated induction of host immune responses 2 10 10.186475409836063 0.0229613270793894 |
| Synthesis of dna 7 117 2.6200076074553063 0.0230184986659368 |
| Cell cycle checkpoints 12 257 2.0313971742543173 0.0219359737278278 |
| Dna replication pre initiation 6 92 2.8674418604651164 0.0236289755936298 |
| Interaction with cumulus cells and the zona pellucida 1 1 inf 0.0241271086695676 |
| Defective b4galt1 causes b4galt1 cdg cdg 2d 1 1 inf 0.0241271086695676 |
| Pyruvate metabolism 3 26 5.328502415458937 0.0239571113561098 |
| Gpcr ligand binding 4 46 3.8992522628886266 0.0244406528674846 |
| M phase 15 355 1.8353705118411 0.0250996119223265 |
| Rho gtpase cycle 16 387 1.7961326614320872 0.0252153451734668 |
| Glycosaminoglycan metabolism 5 70 3.1551228854133417 0.0266777247012389 |
| Synaptic adhesion like molecules 2 11 9.053734061930784 0.0276231155809849 |
| Regulation of innate immune responses to cytosolic dna 2 11 9.053734061930784 0.0276231155809849 |
| Signaling by hedgehog 7 122 2.5048208113516464 0.0281363706052967 |
| Hedgehog off state 6 96 2.738888888888889 0.0284012976090309 |
| Assembly and cell surface presentation of nmda receptors 3 28 4.901234567901234 0.0291459656321865 |
| Programmed cell death 9 179 2.184661206254653 0.029408255458711 |
| Retrograde transport at the trans golgi network 4 49 3.638200183654729 0.0300192966842153 |
| Carnitine metabolism 2 12 8.147540983606557 0.032628233248221 |
| Synthesis of pe 2 12 8.147540983606557 0.032628233248221 |
| Purine salvage 2 12 8.147540983606557 0.032628233248221 |
| Transcriptional regulation by runx2 6 100 2.6212765957446806 0.0337698983302116 |
| Pten regulation 7 128 2.379162488329472 0.0352346724005287 |
| Ion homeostasis 3 31 4.374779541446208 0.0379489226270714 |
| Pre notch processing in golgi 2 13 7.406110283159464 0.0379575415698398 |
| S phase 8 158 2.196078431372549 0.037498269976549 |
| Ion transport by p type atpases 3 31 4.374779541446208 0.0379489226270714 |
| Cytosolic iron sulfur cluster assembly 2 13 7.406110283159464 0.0379575415698398 |
| Cobalamin cbl vitamin b12 transport and metabolism 2 13 7.406110283159464 0.0379575415698398 |
| Apoptosis 8 159 2.181312260003339 0.0386981100045085 |
| Diseases of metabolism 7 131 2.3208935078958026 0.0391925104047672 |
| Antigen processing ubiquitination proteasome degradation 11 250 1.9019140033828896 0.0399017324455896 |
| Dna replication 7 137 2.2124235597038946 0.0479558757106163 |
| Release of hh np from the secreting cell 1 2 40.608163265306125 0.0476744094315084 |
| Scavenging by class b receptors 1 2 40.608163265306125 0.0476744094315084 |
| Hdl clearance 1 2 40.608163265306125 0.0476744094315084 |
| Ion channel transport 5 82 2.6601821415099423 0.0478393395788808 |
| Signaling by rho gtpases miro gtpases and rhobtb3 21 593 1.5302097902097902 0.0496884643595681 |
| Insulin receptor recycling 2 15 6.265447667087011 0.0495157384890535 |
| Mitotic prometaphase 9 198 1.961221619449468 0.0505373960818359 |
| Cytokine signaling in immune system 15 392 1.648868373006304 0.0524142114187797 |
| Mitochondrial biogenesis 5 85 2.559647302904564 0.0543296939149059 |
| Ros and rns production in phagocytes 2 16 5.817330210772834 0.0557098434243155 |
| Role of phospholipids in phagocytosis 2 16 5.817330210772834 0.0557098434243155 |
| Diseases associated with glycosylation precursor biosynthesis 2 16 5.817330210772834 0.0557098434243155 |
| Basigin interactions 2 16 5.817330210772834 0.0557098434243155 |
| Intracellular signaling by second messengers 10 233 1.8482556813863344 0.0558849970455404 |
| Mitochondrial protein import 4 59 2.9737039819684448 0.053649406266927 |
| Sialic acid metabolism 2 16 5.817330210772834 0.0557098434243155 |
| Metabolism of porphyrins 2 17 5.42896174863388 0.0621585272883563 |
| G alpha i signalling events 5 88 2.466380042993551 0.0613062198602933 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 6 116 2.2363636363636363 0.0615701180840998 |
| Post translational protein modification 32 1003 1.382754073746114 0.0609446220741883 |
| Miscellaneous transport and binding events 2 17 5.42896174863388 0.0621585272883563 |
| Amino acid transport across the plasma membrane 2 17 5.42896174863388 0.0621585272883563 |
| Hs gag degradation 2 17 5.42896174863388 0.0621585272883563 |
| Diseases of signal transduction by growth factor receptors and second messengers 13 333 1.6790504291845494 0.0599341973241276 |
| Iron uptake and transport 3 38 3.497354497354497 0.0630731351339203 |
| Beta catenin independent wnt signaling 6 117 2.215990990990991 0.0636539894044474 |
| Arachidonic acid metabolism 2 18 5.089139344262295 0.0688460117016781 |
| Transferrin endocytosis and recycling 2 18 5.089139344262295 0.0688460117016781 |
| Transcriptional regulation by runx1 7 149 2.022983086805351 0.0689889993381015 |
| Phase i functionalization of compounds 3 39 3.399862825788752 0.0671599559498881 |
| Formyl peptide receptors bind formyl peptides and many other ligands 1 3 20.30204081632653 0.0706557803630322 |
| Synthesis of 5 eicosatetraenoic acids 1 3 20.30204081632653 0.0706557803630322 |
| Defects in vitamin and cofactor metabolism 2 18 5.089139344262295 0.0688460117016781 |
| Fertilization 1 3 20.30204081632653 0.0706557803630322 |
| Hydrolysis of lpc 1 3 20.30204081632653 0.0706557803630322 |
| Toxicity of botulinum toxin type d botd 1 3 20.30204081632653 0.0706557803630322 |
| Clathrin mediated endocytosis 6 119 2.1763274336283187 0.0679453030938743 |
| Biological oxidations 5 94 2.2987085645018417 0.076709375362345 |
| Signaling by interleukins 10 248 1.7290984190286285 0.0777592562001356 |
| Metabolism of amino acids and derivatives 11 281 1.6781717888100869 0.0782252231710548 |
| Neddylation 8 185 1.8559559416987133 0.0792422945829929 |
| Nucleotide salvage 2 20 4.522768670309654 0.0828772873031817 |
| Phospholipid metabolism 7 156 1.9265676335963609 0.0834592789547722 |
| Cardiac conduction 3 43 3.058641975308642 0.0846608217542885 |
| Cell surface interactions at the vascular wall 4 70 2.475331830703732 0.0884683246757208 |
| Response to elevated platelet cytosolic ca2 4 71 2.4381398791168127 0.092069152986564 |
| Trafficking of myristoylated proteins to the cilium 1 4 13.533333333333331 0.0930847686914372 |
| Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant 1 4 13.533333333333331 0.0930847686914372 |
| Proton coupled monocarboxylate transport 1 4 13.533333333333331 0.0930847686914372 |
| Metabolism of ingested semet sec mesec into h2se 1 4 13.533333333333331 0.0930847686914372 |
| Fcgamma receptor fcgr dependent phagocytosis 4 72 2.402041808458921 0.0957389801741353 |
| Synthesis of pc 2 22 4.069672131147541 0.097689242801984 |
| Sulfur amino acid metabolism 2 22 4.069672131147541 0.097689242801984 |
| Protein protein interactions at synapses 3 46 2.8443870226815964 0.0989248704147511 |
| Metabolism of steroids 5 103 2.0856973494792106 0.1033455447275472 |
| Diseases of carbohydrate metabolism 2 23 3.875487900078064 0.1053546389470493 |
| Pyruvate metabolism and citric acid tca cycle 3 48 2.7174211248285323 0.1089349903226686 |
| Diseases of glycosylation 4 76 2.267676767676768 0.1110881847348581 |
| Cd163 mediating an anti inflammatory response 1 5 10.148979591836737 0.1149745986461117 |
| Organelle biogenesis and maintenance 10 268 1.5917750624096705 0.1142157172026566 |
| Runx1 regulates estrogen receptor mediated transcription 1 5 10.148979591836737 0.1149745986461117 |
| Fructose metabolism 1 5 10.148979591836737 0.1149745986461117 |
| Formation of xylulose 5 phosphate 1 5 10.148979591836737 0.1149745986461117 |
| Ethanol oxidation 1 5 10.148979591836737 0.1149745986461117 |
| Cargo recognition for clathrin mediated endocytosis 4 78 2.2059414786687515 0.1191496891129861 |
| Pre notch expression and processing 3 50 2.6012608353033886 0.1193188519501932 |
| Hdms demethylate histones 2 25 3.537776193870278 0.1211421538065826 |
| Interferon gamma signaling 3 51 2.546810699588477 0.124643595331372 |
| Leishmania infection 5 110 1.9452677336494764 0.1268300938393218 |
| Interconversion of nucleotide di and triphosphates 2 26 3.3900273224043715 0.1292409073430241 |
| Tcf dependent signaling in response to wnt 6 142 1.8040441176470587 0.128860910029792 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0 18 0.0 1.0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors 0 1 0.0 1.0 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 1 16 2.703401360544217 0.3236592382947187 |
| Negative regulation of met activity 0 20 0.0 1.0 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0 13 0.0 1.0 |
| Met receptor activation 0 4 0.0 1.0 |
| Trna modification in the nucleus and cytosol 0 43 0.0 1.0 |
| Dual incision in tc ner 1 67 0.6112554112554113 0.8063536449390534 |
| Regulation of tp53 activity through phosphorylation 1 82 0.4973041068279163 0.8661154321407631 |
| Signaling by met 1 64 0.6405571752510528 0.7915335109512663 |
| Transcription coupled nucleotide excision repair tc ner 2 82 1.0112704918032789 0.592458577023541 |
| Metabolism of fat soluble vitamins 1 29 1.4463556851311954 0.5079876539292768 |
| Regulation of tp53 expression and degradation 0 33 0.0 1.0 |
| Formation of tc ner pre incision complex 1 53 0.7769230769230769 0.726859415108312 |
| Keratinization 0 24 0.0 1.0 |
| Regulation of tp53 activity through acetylation 0 30 0.0 1.0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Highly calcium permeable nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Regulation of tp53 activity through association with co factors 0 12 0.0 1.0 |
| Regulation of tp53 activity through methylation 0 16 0.0 1.0 |
| Trna modification in the mitochondrion 0 9 0.0 1.0 |
| Tp53 regulates transcription of death receptors and ligands 0 10 0.0 1.0 |
| Gdp fucose biosynthesis 0 6 0.0 1.0 |
| Erbb2 regulates cell motility 0 6 0.0 1.0 |
| Trna processing in the mitochondrion 0 5 0.0 1.0 |
| Trna processing in the nucleus 1 60 0.6842615012106538 0.7700020901590743 |
| Il 6 type cytokine receptor ligand interactions 0 6 0.0 1.0 |
| Rrna modification in the nucleus and cytosol 1 63 0.6509545753785385 0.7863466234909413 |
| Tp53 regulates transcription of cell cycle genes 1 43 0.9628765792031098 0.6508948194595567 |
| Rrna modification in the mitochondrion 0 6 0.0 1.0 |
| Neurexins and neuroligins 1 28 1.5000755857898715 0.4957890007184933 |
| Maturation of sars cov 2 spike protein 0 24 0.0 1.0 |
| Tp53 regulates transcription of dna repair genes 0 61 0.0 1.0 |
| Choline catabolism 0 4 0.0 1.0 |
| Sars cov 2 infection 1 62 0.6616928738708598 0.7810312178815177 |
| Fgfr2 alternative splicing 0 26 0.0 1.0 |
| Interleukin 10 signaling 0 6 0.0 1.0 |
| Signaling by moderate kinase activity braf mutants 1 36 1.156268221574344 0.5855309260576435 |
| Signaling by braf and raf1 fusions 3 53 2.4444444444444446 0.135543868878084 |
| Defective ripk1 mediated regulated necrosis 0 6 0.0 1.0 |
| Interleukin 6 family signaling 0 10 0.0 1.0 |
| Ras signaling downstream of nf1 loss of function variants 0 5 0.0 1.0 |
| Oncogenic mapk signaling 3 66 1.937487752302567 0.2130027955338551 |
| Fanconi anemia pathway 0 36 0.0 1.0 |
| Interleukin 4 and interleukin 13 signaling 1 40 1.037257980115123 0.6242434222626774 |
| Transcriptional regulation of testis differentiation 0 4 0.0 1.0 |
| Tp53 regulates transcription of genes involved in cytochrome c release 0 16 0.0 1.0 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0 11 0.0 1.0 |
| Tp53 regulates transcription of caspase activators and caspases 0 8 0.0 1.0 |
| Synthesis of wybutosine at g37 of trna phe 0 6 0.0 1.0 |
| Complex i biogenesis 3 56 2.305380852550664 0.1524764865133537 |
| Antimicrobial peptides 0 7 0.0 1.0 |
| Maturation of protein 3a 0 5 0.0 1.0 |
| Copi mediated anterograde transport 0 89 0.0 1.0 |
| Propionyl coa catabolism 0 5 0.0 1.0 |
| Histidine catabolism 0 3 0.0 1.0 |
| Branched chain amino acid catabolism 0 22 0.0 1.0 |
| Urea cycle 0 6 0.0 1.0 |
| Galactose catabolism 0 5 0.0 1.0 |
| Fructose catabolism 0 3 0.0 1.0 |
| Glucose metabolism 1 80 0.5099974166881943 0.8593580344299 |
| Inhibition of dna recombination at telomere 0 28 0.0 1.0 |
| Signaling by pdgfr in disease 0 17 0.0 1.0 |
| Gluconeogenesis 0 25 0.0 1.0 |
| Glycogen breakdown glycogenolysis 0 13 0.0 1.0 |
| Glycolysis 1 66 0.6207221350078493 0.8015340371466311 |
| Mitotic spindle checkpoint 4 111 1.520506681084421 0.2797813766918144 |
| Defective f9 activation 0 1 0.0 1.0 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0 11 0.0 1.0 |
| Lysine catabolism 0 11 0.0 1.0 |
| Signaling by kit in disease 0 18 0.0 1.0 |
| Tryptophan catabolism 1 6 8.118367346938776 0.1363381791325428 |
| Creatine metabolism 0 6 0.0 1.0 |
| Translation 2 289 0.2759753241560518 0.9935125005965432 |
| Recycling of eif2 gdp 0 8 0.0 1.0 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0 59 0.0 1.0 |
| Eukaryotic translation initiation 1 116 0.3490683229813665 0.9421185818427228 |
| Rrna processing 3 202 0.6049382716049383 0.8700363401616438 |
| Trna processing 1 109 0.3719576719576719 0.9311947942836822 |
| Processing of capped intron containing pre mrna 5 239 0.861439160194347 0.6885802931240568 |
| Signaling by membrane tethered fusions of pdgfra or pdgfrb 0 3 0.0 1.0 |
| Sealing of the nuclear envelope ne by escrt iii 0 26 0.0 1.0 |
| Mrna editing c to u conversion 0 2 0.0 1.0 |
| Mrna splicing 4 188 0.8772906934962271 0.6692215422242355 |
| Mrna splicing minor pathway 0 52 0.0 1.0 |
| Mrna capping 0 29 0.0 1.0 |
| Citric acid cycle tca cycle 0 21 0.0 1.0 |
| Metabolism of carbohydrates 7 201 1.4728896173920545 0.2124819698546573 |
| Pentose phosphate pathway 0 13 0.0 1.0 |
| Transport of mature transcript to cytoplasm 2 81 1.024175140070554 0.5857485166130989 |
| G2 m dna replication checkpoint 0 5 0.0 1.0 |
| G2 m dna damage checkpoint 2 66 1.2661372950819672 0.4755559518983523 |
| Signaling by csf3 g csf 0 22 0.0 1.0 |
| Mitotic prophase 1 93 0.4373558118899733 0.8978967157475708 |
| Maturation of sars cov 1 nucleoprotein 0 9 0.0 1.0 |
| Cdc6 association with the orc origin complex 0 12 0.0 1.0 |
| Assembly of the orc complex at the origin of replication 0 20 0.0 1.0 |
| Presynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Glycerophospholipid catabolism 0 4 0.0 1.0 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0 27 0.0 1.0 |
| Mitotic telophase cytokinesis 1 13 3.380272108843537 0.2721697661507766 |
| Pi5p regulates tp53 acetylation 0 9 0.0 1.0 |
| Intra golgi and retrograde golgi to er traffic 6 181 1.3964285714285714 0.2722122757054931 |
| Translation of sars cov 1 structural proteins 0 22 0.0 1.0 |
| Intra golgi traffic 1 42 0.986460925833748 0.6422270888991375 |
| Copi independent golgi to er retrograde traffic 0 45 0.0 1.0 |
| Copi dependent golgi to er retrograde traffic 1 83 0.4911896465903435 0.8693718691208461 |
| Formation of the cornified envelope 0 24 0.0 1.0 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 0 20 0.0 1.0 |
| Maturation of sars cov 1 spike protein 0 5 0.0 1.0 |
| Rna polymerase ii transcribes snrna genes 0 73 0.0 1.0 |
| Flt3 signaling in disease 0 22 0.0 1.0 |
| Sars cov infections 3 128 0.9703703703703704 0.6006618364793616 |
| Nervous system development 11 443 1.0313041765169424 0.5052776405900101 |
| Cell cycle mitotic 16 498 1.366480245354501 0.1485234972282667 |
| Cyclin a b1 b2 associated events during g2 m transition 0 24 0.0 1.0 |
| Diseases of mitotic cell cycle 0 38 0.0 1.0 |
| Diseases of dna repair 1 33 1.2650510204081633 0.5539124029112868 |
| Cyclin d associated events in g1 0 45 0.0 1.0 |
| G1 s specific transcription 0 29 0.0 1.0 |
| G2 phase 0 4 0.0 1.0 |
| Dna strand elongation 1 35 1.190396158463385 0.5752475783862557 |
| Processive synthesis on the lagging strand 0 17 0.0 1.0 |
| Polymerase switching 1 16 2.703401360544217 0.3236592382947187 |
| Sars cov 1 infection 1 42 0.986460925833748 0.6422270888991375 |
| Potential therapeutics for sars 2 68 1.2275211127670145 0.4912505524209553 |
| Activation of the pre replicative complex 0 33 0.0 1.0 |
| Translation of replicase and assembly of the replication transcription complex 1 13 3.380272108843537 0.2721697661507766 |
| Dna replication initiation 0 8 0.0 1.0 |
| Lagging strand synthesis 1 23 1.8419294990723565 0.4301270919610729 |
| Inflammasomes 1 12 3.687940630797774 0.2541534411772372 |
| Nonhomologous end joining nhej 2 41 2.0830180748213536 0.260178364686727 |
| Attachment and entry 0 4 0.0 1.0 |
| Tnfr1 mediated ceramide production 0 3 0.0 1.0 |
| Rho gtpases activate iqgaps 1 26 1.620408163265306 0.4704807306772423 |
| Rho gtpases activate ktn1 1 11 4.057142857142857 0.2356930071839008 |
| Rho gtpases activate cit 1 18 2.384873949579832 0.3559534457378639 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0 14 0.0 1.0 |
| Rho gtpases activate pkns 1 40 1.037257980115123 0.6242434222626774 |
| Cd209 dc sign signaling 0 18 0.0 1.0 |
| Rho gtpases activate rocks 1 19 2.2521541950113377 0.3715199079432311 |
| Heme signaling 0 36 0.0 1.0 |
| Regulation of bach1 activity 0 10 0.0 1.0 |
| Pyroptosis 0 16 0.0 1.0 |
| Intraflagellar transport 0 48 0.0 1.0 |
| Sensory perception 1 84 0.4852225227440374 0.8725494148729388 |
| Bbsome mediated cargo targeting to cilium 0 18 0.0 1.0 |
| Cargo trafficking to the periciliary membrane 1 43 0.9628765792031098 0.6508948194595567 |
| Cellular response to starvation 1 139 0.2902099970422951 0.9672305971958756 |
| Dectin 2 family 0 4 0.0 1.0 |
| Rho gtpases activate paks 1 19 2.2521541950113377 0.3715199079432311 |
| Tp53 regulates metabolic genes 1 84 0.4852225227440374 0.8725494148729388 |
| Rhobtb gtpase cycle 1 33 1.2650510204081633 0.5539124029112868 |
| Negative regulation of flt3 0 8 0.0 1.0 |
| Pi 3k cascade fgfr1 0 8 0.0 1.0 |
| Flt3 signaling through src family kinases 0 2 0.0 1.0 |
| Shc mediated cascade fgfr1 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr1 0 15 0.0 1.0 |
| Phospholipase c mediated cascade fgfr4 0 3 0.0 1.0 |
| Phospholipase c mediated cascade fgfr2 0 3 0.0 1.0 |
| Vesicle mediated transport 15 546 1.1518331009856433 0.3391224277718983 |
| Pcna dependent long patch base excision repair 1 24 1.7616681455190772 0.4439075633632242 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0 7 0.0 1.0 |
| Constitutive signaling by egfrviii 0 14 0.0 1.0 |
| Gli proteins bind promoters of hh responsive genes to promote transcription 0 2 0.0 1.0 |
| Activation of smo 0 11 0.0 1.0 |
| Tp53 regulates transcription of cell death genes 0 34 0.0 1.0 |
| Regulation of tp53 activity 1 146 0.2760028149190711 0.972447592207374 |
| Flt3 signaling by cbl mutants 0 4 0.0 1.0 |
| Ligand receptor interactions 0 2 0.0 1.0 |
| Vxpx cargo targeting to cilium 0 18 0.0 1.0 |
| Anchoring of the basal body to the plasma membrane 4 95 1.790754699845609 0.1965656491382458 |
| Miro gtpase cycle 0 8 0.0 1.0 |
| Slc transporter disorders 2 54 1.5602143757881464 0.3757594500595086 |
| Phase 3 rapid repolarisation 0 1 0.0 1.0 |
| Phase 4 resting membrane potential 0 2 0.0 1.0 |
| Growth hormone receptor signaling 1 15 2.896793002915452 0.3069124011154697 |
| Organic cation anion zwitterion transport 0 3 0.0 1.0 |
| Organic cation transport 0 3 0.0 1.0 |
| Aflatoxin activation and detoxification 0 6 0.0 1.0 |
| Diseases of mismatch repair mmr 0 5 0.0 1.0 |
| Negative regulation of tcf dependent signaling by dvl interacting proteins 0 5 0.0 1.0 |
| Mitochondrial translation 1 93 0.4373558118899733 0.8978967157475708 |
| Ra biosynthesis pathway 1 9 5.072448979591837 0.1973959389561772 |
| Kinesins 0 47 0.0 1.0 |
| Signaling by retinoic acid 1 26 1.620408163265306 0.4704807306772423 |
| Mismatch repair 1 17 2.534183673469388 0.3400030327298383 |
| Synthesis of diphthamide eef2 0 8 0.0 1.0 |
| Factors involved in megakaryocyte development and platelet production 1 117 0.3460239268121041 0.9435311640733663 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 1 20 2.133404940923738 0.3867116248199588 |
| Tnfr1 induced nfkappab signaling pathway 0 28 0.0 1.0 |
| Phase 0 rapid depolarisation 1 6 8.118367346938776 0.1363381791325428 |
| Frs mediated fgfr1 signaling 0 9 0.0 1.0 |
| Phase 2 plateau phase 0 3 0.0 1.0 |
| Physiological factors 0 6 0.0 1.0 |
| Sensory perception of taste 0 4 0.0 1.0 |
| Cilium assembly 5 183 1.1389808382675184 0.4533933095675377 |
| Nuclear events stimulated by alk signaling in cancer 0 17 0.0 1.0 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 1 60 0.6842615012106538 0.7700020901590743 |
| Defective intrinsic pathway for apoptosis 1 24 1.7616681455190772 0.4439075633632242 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0 10 0.0 1.0 |
| Reactions specific to the complex n glycan synthesis pathway 1 6 8.118367346938776 0.1363381791325428 |
| Termination of o glycan biosynthesis 0 4 0.0 1.0 |
| Amyloid fiber formation 1 41 1.0112244897959184 0.6333450487016228 |
| Clec7a dectin 1 induces nfat activation 1 10 4.508390022675737 0.2167775624926856 |
| Serine biosynthesis 0 7 0.0 1.0 |
| Irak4 deficiency tlr2 4 0 4 0.0 1.0 |
| Ikba variant leads to eda id 0 7 0.0 1.0 |
| Gaba receptor activation 0 18 0.0 1.0 |
| Piwi interacting rna pirna biogenesis 1 16 2.703401360544217 0.3236592382947187 |
| Metabolic disorders of biological oxidation enzymes 0 13 0.0 1.0 |
| Gaba b receptor activation 0 16 0.0 1.0 |
| Transcriptional regulation by small rnas 1 57 0.7211370262390671 0.7524126639072135 |
| Pi 3k cascade fgfr2 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr2 0 14 0.0 1.0 |
| Frs mediated fgfr2 signaling 0 9 0.0 1.0 |
| Translation of sars cov 2 structural proteins 0 41 0.0 1.0 |
| Josephin domain dubs 0 9 0.0 1.0 |
| Rnd3 gtpase cycle 2 39 2.196056712450155 0.2421879711614701 |
| Rnd2 gtpase cycle 2 40 2.1380500431406384 0.2511786735203468 |
| Diseases associated with surfactant metabolism 0 1 0.0 1.0 |
| Rnd1 gtpase cycle 2 36 2.390549662487946 0.2153304097941032 |
| Regulation of tlr by endogenous ligand 0 3 0.0 1.0 |
| Hdr through homologous recombination hrr 2 66 1.2661372950819672 0.4755559518983523 |
| Hdr through mmej alt nhej 0 11 0.0 1.0 |
| Hdr through single strand annealing ssa 1 35 1.190396158463385 0.5752475783862557 |
| Map3k8 tpl2 dependent mapk1 3 activation 0 14 0.0 1.0 |
| Surfactant metabolism 1 8 5.797667638483965 0.1775366954381628 |
| Signaling by alk in cancer 1 52 0.7922368947579032 0.7200709140128994 |
| Lgi adam interactions 0 5 0.0 1.0 |
| Alk mutants bind tkis 0 12 0.0 1.0 |
| Protein repair 0 5 0.0 1.0 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 0 5 0.0 1.0 |
| Ovarian tumor domain proteases 0 34 0.0 1.0 |
| Negative regulation of mapk pathway 0 36 0.0 1.0 |
| Metalloprotease dubs 0 20 0.0 1.0 |
| Dna double strand break repair 4 137 1.220033554961785 0.4220997831792236 |
| Deposition of new cenpa containing nucleosomes at the centromere 2 34 2.54047131147541 0.1975866021584996 |
| Dual incision in gg ner 1 42 0.986460925833748 0.6422270888991375 |
| Global genome nucleotide excision repair gg ner 3 87 1.450029394473839 0.3505166983265811 |
| Nucleotide excision repair 3 114 1.0943165387609832 0.5218778121271003 |
| Gap filling dna repair synthesis and ligation in gg ner 1 28 1.5000755857898715 0.4957890007184933 |
| Formation of incision complex in gg ner 0 42 0.0 1.0 |
| Dna damage recognition in gg ner 2 37 2.322014051522248 0.224257489169728 |
| Cargo concentration in the er 0 23 0.0 1.0 |
| Processing of dna double strand break ends 2 66 1.2661372950819672 0.4755559518983523 |
| Dna double strand break response 1 49 0.8420068027210884 0.6986806537780095 |
| Homologous dna pairing and strand exchange 1 41 1.0112244897959184 0.6333450487016228 |
| Transport of nucleotide sugars 0 4 0.0 1.0 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 1 26 1.620408163265306 0.4704807306772423 |
| Sensing of dna double strand breaks 0 6 0.0 1.0 |
| Maturation of sars cov 2 nucleoprotein 0 13 0.0 1.0 |
| Homology directed repair 3 106 1.180270885772504 0.473282493679958 |
| Resolution of d loop structures 1 32 1.3059907834101383 0.5428479192551358 |
| Cd22 mediated bcr regulation 0 2 0.0 1.0 |
| Respiratory electron transport 3 101 1.2411186696900982 0.4418071915292876 |
| Negative feedback regulation of mapk pathway 0 6 0.0 1.0 |
| Map2k and mapk activation 0 31 0.0 1.0 |
| Signaling by fgfr3 0 27 0.0 1.0 |
| Signaling by fgfr2 0 51 0.0 1.0 |
| Signaling by fgfr1 0 28 0.0 1.0 |
| Negative regulation of fgfr4 signaling 0 17 0.0 1.0 |
| Negative regulation of fgfr3 signaling 0 17 0.0 1.0 |
| Negative regulation of fgfr2 signaling 0 17 0.0 1.0 |
| Negative regulation of fgfr1 signaling 0 17 0.0 1.0 |
| Pi 3k cascade fgfr4 0 8 0.0 1.0 |
| Shc mediated cascade fgfr4 0 8 0.0 1.0 |
| Inactivation of csf3 g csf signaling 0 17 0.0 1.0 |
| Downstream signaling of activated fgfr4 0 14 0.0 1.0 |
| Frs mediated fgfr4 signaling 0 9 0.0 1.0 |
| Pi 3k cascade fgfr3 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr3 0 14 0.0 1.0 |
| Rhobtb3 atpase cycle 0 9 0.0 1.0 |
| Frs mediated fgfr3 signaling 0 9 0.0 1.0 |
| Shc mediated cascade fgfr3 0 8 0.0 1.0 |
| Signaling by fgfr4 0 26 0.0 1.0 |
| Constitutive signaling by akt1 e17k in cancer 0 25 0.0 1.0 |
| Signaling by fgfr2 in disease 0 28 0.0 1.0 |
| Signaling by fgfr1 in disease 0 29 0.0 1.0 |
| Raf activation 1 33 1.2650510204081633 0.5539124029112868 |
| Tnfs bind their physiological receptors 0 1 0.0 1.0 |
| Stat3 nuclear events downstream of alk signaling 0 6 0.0 1.0 |
| Rho gtpases activate nadph oxidases 0 13 0.0 1.0 |
| Stat5 activation downstream of flt3 itd mutants 0 6 0.0 1.0 |
| Rho gtpases activate rhotekin and rhophilins 0 8 0.0 1.0 |
| Rho gtpases activate formins 4 133 1.2583765776154785 0.4002941846414097 |
| Rho gtpases activate wasps and waves 1 33 1.2650510204081633 0.5539124029112868 |
| Infectious disease 18 619 1.228084770995709 0.2378697562238813 |
| Metallothioneins bind metals 0 2 0.0 1.0 |
| Clec7a inflammasome pathway 0 4 0.0 1.0 |
| Response to metal ions 0 5 0.0 1.0 |
| Fgfrl1 modulation of fgfr1 signaling 0 2 0.0 1.0 |
| Signaling by flt3 fusion proteins 0 16 0.0 1.0 |
| Signaling by flt3 itd and tkd mutants 0 12 0.0 1.0 |
| Termination of translesion dna synthesis 1 34 1.2265924551638838 0.5647101544543685 |
| Translesion synthesis by polk 1 17 2.534183673469388 0.3400030327298383 |
| Signaling by fgfr4 in disease 0 11 0.0 1.0 |
| Pyrimidine salvage 0 9 0.0 1.0 |
| Transcriptional regulation of granulopoiesis 0 34 0.0 1.0 |
| Rna polymerase i transcription initiation 0 49 0.0 1.0 |
| Rhoq gtpase cycle 3 59 2.181216931216931 0.1700362094205073 |
| Rhod gtpase cycle 1 50 0.8247396917950853 0.705985725150242 |
| Rac2 gtpase cycle 3 81 1.562519784742007 0.3107114949655366 |
| Rac1 gtpase cycle 3 152 0.8120805369127517 0.714626429470328 |
| Cdc42 gtpase cycle 4 134 1.2485696122059755 0.4057604474152967 |
| Rhoc gtpase cycle 2 75 1.109027621827981 0.5437935802005475 |
| Rhob gtpase cycle 2 69 1.2090775630046489 0.4989867787620257 |
| Rhoh gtpase cycle 1 32 1.3059907834101383 0.5428479192551358 |
| Modulation by mtb of host immune system 0 4 0.0 1.0 |
| Robo receptors bind akap5 0 8 0.0 1.0 |
| Regulation of expression of slits and robos 6 155 1.644463087248322 0.1719391325579152 |
| Calnexin calreticulin cycle 1 23 1.8419294990723565 0.4301270919610729 |
| Er quality control compartment erqc 1 18 2.384873949579832 0.3559534457378639 |
| Extra nuclear estrogen signaling 0 47 0.0 1.0 |
| Interleukin 37 signaling 0 12 0.0 1.0 |
| Rab regulation of trafficking 0 107 0.0 1.0 |
| Signaling by notch3 1 35 1.190396158463385 0.5752475783862557 |
| Rhog gtpase cycle 3 71 1.7941176470588236 0.244978619195686 |
| Rhoj gtpase cycle 3 55 2.3499525166191835 0.1467586347483675 |
| Prevention of phagosomal lysosomal fusion 0 8 0.0 1.0 |
| Noncanonical activation of notch3 0 8 0.0 1.0 |
| Interleukin 36 pathway 0 1 0.0 1.0 |
| Ticam1 traf6 dependent induction of tak1 complex 0 10 0.0 1.0 |
| Ticam1 dependent activation of irf3 irf7 0 10 0.0 1.0 |
| Tlr3 mediated ticam1 dependent programmed cell death 0 5 0.0 1.0 |
| Notch4 activation and transmission of signal to the nucleus 0 8 0.0 1.0 |
| Notch4 intracellular domain regulates transcription 1 15 2.896793002915452 0.3069124011154697 |
| Suppression of apoptosis 0 6 0.0 1.0 |
| Notch3 intracellular domain regulates transcription 1 18 2.384873949579832 0.3559534457378639 |
| Notch3 activation and transmission of signal to the nucleus 0 18 0.0 1.0 |
| Rhot1 gtpase cycle 0 5 0.0 1.0 |
| Rhov gtpase cycle 1 35 1.190396158463385 0.5752475783862557 |
| Rac3 gtpase cycle 2 83 0.9986844768265534 0.5990875991193605 |
| Rhobtb1 gtpase cycle 1 22 1.9298347910592808 0.4160065505344545 |
| Rhou gtpase cycle 0 39 0.0 1.0 |
| Rhobtb2 gtpase cycle 0 22 0.0 1.0 |
| Infection with mycobacterium tuberculosis 0 21 0.0 1.0 |
| Signaling by tgfb family members 1 79 0.5165881737310308 0.8558530274917338 |
| Signaling by receptor tyrosine kinases 7 344 0.8354667693033535 0.7294622950555637 |
| Signaling by nuclear receptors 3 178 0.689594356261023 0.8080020032452987 |
| Signaling by erythropoietin 0 19 0.0 1.0 |
| Ldl clearance 0 17 0.0 1.0 |
| Amino acids regulate mtorc1 1 45 0.9189239332096476 0.6676078298658026 |
| Chylomicron clearance 0 4 0.0 1.0 |
| Stat5 activation 0 4 0.0 1.0 |
| Chylomicron remodeling 0 4 0.0 1.0 |
| Plasma lipoprotein remodeling 0 12 0.0 1.0 |
| Plasma lipoprotein assembly 0 12 0.0 1.0 |
| Hdl assembly 0 6 0.0 1.0 |
| Assembly of active lpl and lipc lipase complexes 0 7 0.0 1.0 |
| Chylomicron assembly 0 5 0.0 1.0 |
| Digestion and absorption 0 1 0.0 1.0 |
| Aspartate and asparagine metabolism 0 7 0.0 1.0 |
| Phenylalanine and tyrosine metabolism 0 6 0.0 1.0 |
| Tyrosine catabolism 0 2 0.0 1.0 |
| Nucleotide biosynthesis 0 16 0.0 1.0 |
| Nucleotide catabolism 0 22 0.0 1.0 |
| Carboxyterminal post translational modifications of tubulin 0 25 0.0 1.0 |
| Ldl remodeling 0 2 0.0 1.0 |
| Estrogen dependent gene expression 1 90 0.4522357257509745 0.8900614345422548 |
| Plasma lipoprotein clearance 1 23 1.8419294990723565 0.4301270919610729 |
| Hdl remodeling 0 3 0.0 1.0 |
| Signaling by ntrk2 trkb 0 18 0.0 1.0 |
| Loss of function of mecp2 in rett syndrome 0 12 0.0 1.0 |
| Transcriptional regulation by mecp2 1 45 0.9189239332096476 0.6676078298658026 |
| Interleukin 9 signaling 0 4 0.0 1.0 |
| Interleukin 35 signalling 0 9 0.0 1.0 |
| Oas antiviral response 0 6 0.0 1.0 |
| Interleukin 15 signaling 0 8 0.0 1.0 |
| Glycogen metabolism 0 20 0.0 1.0 |
| Rhoa gtpase cycle 5 134 1.5794975714883075 0.2226406444315481 |
| Suppression of phagosomal maturation 0 11 0.0 1.0 |
| Triglyceride metabolism 1 20 2.133404940923738 0.3867116248199588 |
| Metabolism of cofactors 0 15 0.0 1.0 |
| Response of mtb to phagocytosis 0 20 0.0 1.0 |
| G beta gamma signalling through cdc42 0 14 0.0 1.0 |
| Lipid particle organization 0 1 0.0 1.0 |
| Glutamate and glutamine metabolism 0 14 0.0 1.0 |
| Phenylalanine metabolism 0 4 0.0 1.0 |
| Vldl clearance 0 4 0.0 1.0 |
| Cellular responses to stimuli 12 614 0.7963199591106568 0.8140422654016886 |
| Biosynthesis of specialized proresolving mediators spms 0 6 0.0 1.0 |
| Biosynthesis of maresins 0 1 0.0 1.0 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 0 11 0.0 1.0 |
| Irak2 mediated activation of tak1 complex 0 9 0.0 1.0 |
| Ikk complex recruitment mediated by rip1 0 16 0.0 1.0 |
| Irak1 recruits ikk complex 0 12 0.0 1.0 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0 11 0.0 1.0 |
| Negative regulators of ddx58 ifih1 signaling 0 29 0.0 1.0 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0 13 0.0 1.0 |
| Molybdenum cofactor biosynthesis 0 7 0.0 1.0 |
| Traf6 mediated nf kb activation 1 22 1.9298347910592808 0.4160065505344545 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 0 6 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis 0 4 0.0 1.0 |
| Nonsense mediated decay nmd 0 110 0.0 1.0 |
| Response of eif2ak4 gcn2 to amino acid deficiency 0 94 0.0 1.0 |
| Traf3 dependent irf activation pathway 0 13 0.0 1.0 |
| Endosomal sorting complex required for transport escrt 0 30 0.0 1.0 |
| O linked glycosylation of mucins 1 22 1.9298347910592808 0.4160065505344545 |
| Traf6 mediated irf7 activation 0 15 0.0 1.0 |
| Transport to the golgi and subsequent modification 4 148 1.1255739210284663 0.4809185087869787 |
| Activated ntrk3 signals through pi3k 0 4 0.0 1.0 |
| Class i peroxisomal membrane protein import 1 19 2.2521541950113377 0.3715199079432311 |
| Postmitotic nuclear pore complex npc reformation 1 27 1.5579277864992152 0.4832891613764908 |
| Late endosomal microautophagy 1 29 1.4463556851311954 0.5079876539292768 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0 18 0.0 1.0 |
| Foxo mediated transcription of cell death genes 0 12 0.0 1.0 |
| Regulation of localization of foxo transcription factors 0 13 0.0 1.0 |
| Foxo mediated transcription 0 47 0.0 1.0 |
| Chaperone mediated autophagy 1 16 2.703401360544217 0.3236592382947187 |
| Lipophagy 0 8 0.0 1.0 |
| Autophagy 3 130 0.9548945270730048 0.6112014428339826 |
| Hcmv late events 1 62 0.6616928738708598 0.7810312178815177 |
| Foxo mediated transcription of cell cycle genes 0 13 0.0 1.0 |
| Hcmv early events 2 79 1.0509899936129443 0.5720855777628291 |
| Hcmv infection 2 102 0.8073770491803278 0.7098691613598352 |
| Activation of rac1 downstream of nmdars 0 6 0.0 1.0 |
| Activation of ampk downstream of nmdars 0 21 0.0 1.0 |
| Flt3 signaling 0 27 0.0 1.0 |
| Diseases of base excision repair 0 4 0.0 1.0 |
| Interferon signaling 4 128 1.309784057584644 0.3728569773131227 |
| Regulation of ifna signaling 0 8 0.0 1.0 |
| Constitutive signaling by overexpressed erbb2 0 11 0.0 1.0 |
| Regulation of signaling by cbl 0 18 0.0 1.0 |
| Erythropoietin activates stat5 0 4 0.0 1.0 |
| Erythropoietin activates phospholipase c gamma plcg 0 5 0.0 1.0 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 8 0.0 1.0 |
| Activated ntrk2 signals through ras 0 6 0.0 1.0 |
| Nr1h2 and nr1h3 mediated signaling 1 31 1.349659863945578 0.5315101420828222 |
| Mecp2 regulates transcription factors 0 4 0.0 1.0 |
| Mecp2 regulates transcription of neuronal ligands 0 4 0.0 1.0 |
| Mecp2 regulates neuronal receptors and channels 0 12 0.0 1.0 |
| Regulation of mecp2 expression and activity 1 30 1.3963406052076002 0.5198923492291299 |
| Loss of mecp2 binding ability to the ncor smrt complex 0 7 0.0 1.0 |
| Interleukin 21 signaling 0 5 0.0 1.0 |
| Interleukin 27 signaling 0 8 0.0 1.0 |
| Interleukin 23 signaling 0 5 0.0 1.0 |
| Estrogen stimulated signaling through prkcz 0 6 0.0 1.0 |
| Interleukin 12 signaling 2 38 2.2572859744990894 0.2332121755087385 |
| Interleukin 2 signaling 0 5 0.0 1.0 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 0 15 0.0 1.0 |
| Erythropoietin activates ras 0 11 0.0 1.0 |
| Biosynthesis of epa derived spms 0 3 0.0 1.0 |
| Activated ntrk2 signals through pi3k 0 4 0.0 1.0 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0 11 0.0 1.0 |
| Interleukin receptor shc signaling 0 14 0.0 1.0 |
| Meiotic recombination 0 31 0.0 1.0 |
| Interferon alpha beta signaling 1 31 1.349659863945578 0.5315101420828222 |
| Rhof gtpase cycle 0 42 0.0 1.0 |
| Activated ntrk3 signals through ras 0 6 0.0 1.0 |
| Signaling by ntrk3 trkc 0 15 0.0 1.0 |
| Blood group systems biosynthesis 0 5 0.0 1.0 |
| Tysnd1 cleaves peroxisomal proteins 0 7 0.0 1.0 |
| Peroxisomal protein import 1 51 0.8081632653061225 0.713114397687874 |
| Activated ntrk2 signals through cdk5 0 3 0.0 1.0 |
| Ntrk2 activates rac1 0 3 0.0 1.0 |
| Activated ntrk2 signals through fyn 0 4 0.0 1.0 |
| Ngf stimulated transcription 0 22 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose 0 3 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake 0 3 0.0 1.0 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 1 26 1.620408163265306 0.4704807306772423 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0 7 0.0 1.0 |
| Activated ntrk2 signals through frs2 and frs3 0 7 0.0 1.0 |
| Pyrimidine catabolism 0 6 0.0 1.0 |
| Alpha protein kinase 1 signaling pathway 0 9 0.0 1.0 |
| Metabolism of rna 15 647 0.9573812263685682 0.6024423963560293 |
| Transport of fatty acids 0 3 0.0 1.0 |
| Processing of intronless pre mrnas 1 21 2.026530612244898 0.4015375820029667 |
| Slbp dependent processing of replication dependent histone pre mrnas 0 10 0.0 1.0 |
| Beta oxidation of butanoyl coa to acetyl coa 0 5 0.0 1.0 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0 5 0.0 1.0 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0 5 0.0 1.0 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0 6 0.0 1.0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0 8 0.0 1.0 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0 4 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0 5 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0 9 0.0 1.0 |
| Synthesis of ketone bodies 0 6 0.0 1.0 |
| Rna polymerase iii transcription initiation from type 3 promoter 0 30 0.0 1.0 |
| Rna polymerase iii transcription initiation from type 1 promoter 0 31 0.0 1.0 |
| Platelet aggregation plug formation 0 20 0.0 1.0 |
| Platelet activation signaling and aggregation 5 152 1.3835492703305388 0.305155459734769 |
| Mitochondrial fatty acid beta oxidation 0 33 0.0 1.0 |
| The nlrp3 inflammasome 1 10 4.508390022675737 0.2167775624926856 |
| Regulation of ifng signaling 0 10 0.0 1.0 |
| Advanced glycosylation endproduct receptor signaling 1 9 5.072448979591837 0.1973959389561772 |
| Met activates pi3k akt signaling 0 6 0.0 1.0 |
| Met activates ras signaling 0 11 0.0 1.0 |
| Regulation of tnfr1 signaling 1 31 1.349659863945578 0.5315101420828222 |
| Signaling by fgfr2 iiia tm 0 18 0.0 1.0 |
| Butyrophilin btn family interactions 0 5 0.0 1.0 |
| Phosphate bond hydrolysis by ntpdase proteins 0 4 0.0 1.0 |
| Anti inflammatory response favouring leishmania parasite infection 2 46 1.8453800298062597 0.3051232152156647 |
| Ptk6 expression 0 2 0.0 1.0 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 1 13 3.380272108843537 0.2721697661507766 |
| Ptk6 regulates cell cycle 0 5 0.0 1.0 |
| Ptk6 regulates rtks and their effectors akt1 and dok1 0 7 0.0 1.0 |
| Ptk6 regulates proteins involved in rna processing 0 3 0.0 1.0 |
| Wax and plasmalogen biosynthesis 0 5 0.0 1.0 |
| Signaling by ptk6 1 36 1.156268221574344 0.5855309260576435 |
| Erbb2 activates ptk6 signaling 0 3 0.0 1.0 |
| Gastrin creb signalling pathway via pkc and mapk 0 14 0.0 1.0 |
| Transport of organic anions 0 3 0.0 1.0 |
| Tnf signaling 2 39 2.196056712450155 0.2421879711614701 |
| Platelet adhesion to exposed collagen 0 7 0.0 1.0 |
| Synthesis of very long chain fatty acyl coas 0 17 0.0 1.0 |
| Dissolution of fibrin clot 0 7 0.0 1.0 |
| Resolution of abasic sites ap sites 1 41 1.0112244897959184 0.6333450487016228 |
| Base excision repair ap site formation 0 23 0.0 1.0 |
| Regulation of foxo transcriptional activity by acetylation 0 10 0.0 1.0 |
| Dna damage bypass 1 49 0.8420068027210884 0.6986806537780095 |
| Death receptor signalling 2 120 0.6829674909697138 0.790120771265211 |
| Pexophagy 0 9 0.0 1.0 |
| Signaling by erbb2 ecd mutants 0 15 0.0 1.0 |
| Chromosome maintenance 3 100 1.2540409825633194 0.435424260519051 |
| Base excision repair 1 55 0.7479969765684051 0.7399484418736413 |
| Rna polymerase i transcription 0 63 0.0 1.0 |
| Rna polymerase i transcription termination 0 32 0.0 1.0 |
| Rna polymerase ii transcription 15 969 0.6123226877943859 0.9799869187026355 |
| Rna polymerase ii transcription termination 1 66 0.6207221350078493 0.8015340371466311 |
| Purine ribonucleoside monophosphate biosynthesis 0 11 0.0 1.0 |
| Defective factor ix causes hemophilia b 0 3 0.0 1.0 |
| Rna polymerase iii chain elongation 0 19 0.0 1.0 |
| Rna polymerase i promoter escape 0 42 0.0 1.0 |
| Dna damage reversal 0 8 0.0 1.0 |
| Protein ubiquitination 0 58 0.0 1.0 |
| Killing mechanisms 0 9 0.0 1.0 |
| Parasite infection 2 50 1.690915300546448 0.3407321567572847 |
| Trail signaling 0 6 0.0 1.0 |
| Fasl cd95l signaling 0 5 0.0 1.0 |
| Apoptotic execution phase 2 47 1.8041894353369765 0.3140672800286707 |
| Selective autophagy 2 67 1.246532156368222 0.4834399233654581 |
| Triglyceride biosynthesis 1 7 6.764625850340136 0.1571881112173651 |
| Fatty acyl coa biosynthesis 2 29 3.012446873102611 0.154226710893935 |
| Mrna editing 0 4 0.0 1.0 |
| Processing of capped intronless pre mrna 1 29 1.4463556851311954 0.5079876539292768 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0 14 0.0 1.0 |
| Signaling by insulin receptor 2 45 1.8884864658787648 0.2961580697833918 |
| Insulin receptor signalling cascade 0 31 0.0 1.0 |
| Signal attenuation 0 9 0.0 1.0 |
| Irs activation 0 4 0.0 1.0 |
| Purine catabolism 0 14 0.0 1.0 |
| Fcgr3a mediated il10 synthesis 1 23 1.8419294990723565 0.4301270919610729 |
| Ketone body metabolism 0 7 0.0 1.0 |
| Rna polymerase iii transcription 0 44 0.0 1.0 |
| Rna polymerase iii transcription termination 0 24 0.0 1.0 |
| Diseases of programmed cell death 2 53 1.5909675345548056 0.3670688568616856 |
| Signaling by mst1 0 3 0.0 1.0 |
| Ret signaling 0 26 0.0 1.0 |
| Runx2 regulates bone development 0 26 0.0 1.0 |
| Signaling by mapk mutants 0 4 0.0 1.0 |
| Runx2 regulates chondrocyte maturation 0 3 0.0 1.0 |
| Runx2 regulates osteoblast differentiation 0 20 0.0 1.0 |
| Runx1 regulates transcription of genes involved in wnt signaling 0 3 0.0 1.0 |
| Runx1 regulates transcription of genes involved in interleukin signaling 0 4 0.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0 5 0.0 1.0 |
| Runx2 regulates genes involved in cell migration 0 5 0.0 1.0 |
| Runx1 regulates transcription of genes involved in bcr signaling 0 4 0.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of keratinocytes 0 4 0.0 1.0 |
| Sensory processing of sound 0 40 0.0 1.0 |
| Esr mediated signaling 1 136 0.2967498110355253 0.9647038322361232 |
| Aryl hydrocarbon receptor signalling 0 7 0.0 1.0 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0 39 0.0 1.0 |
| Runx1 regulates expression of components of tight junctions 0 4 0.0 1.0 |
| Digestion 0 1 0.0 1.0 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0 36 0.0 1.0 |
| Runx3 regulates cdkn1a transcription 0 7 0.0 1.0 |
| Runx3 regulates notch signaling 1 11 4.057142857142857 0.2356930071839008 |
| Defects of contact activation system cas and kallikrein kinin system kks 0 5 0.0 1.0 |
| Transcriptional regulation by e2f6 1 34 1.2265924551638838 0.5647101544543685 |
| Runx3 regulates bcl2l11 bim transcription 0 5 0.0 1.0 |
| Runx3 regulates p14 arf 0 11 0.0 1.0 |
| Runx3 regulates yap1 mediated transcription 0 6 0.0 1.0 |
| Runx3 regulates wnt signaling 0 8 0.0 1.0 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 2 33 2.622686409307245 0.1887844423268079 |
| Processing of smdt1 1 16 2.703401360544217 0.3236592382947187 |
| Aggrephagy 1 34 1.2265924551638838 0.5647101544543685 |
| Runx3 regulates immune response and cell migration 0 4 0.0 1.0 |
| N glycan trimming and elongation in the cis golgi 0 4 0.0 1.0 |
| Ras processing 1 19 2.2521541950113377 0.3715199079432311 |
| Regulation of pten localization 0 8 0.0 1.0 |
| Competing endogenous rnas cernas regulate pten translation 0 8 0.0 1.0 |
| Collagen chain trimerization 0 13 0.0 1.0 |
| Response of eif2ak1 hri to heme deficiency 0 10 0.0 1.0 |
| Regulation of pten gene transcription 1 56 0.7343228200371058 0.7462567628712866 |
| Regulation of pten mrna translation 0 9 0.0 1.0 |
| Receptor mediated mitophagy 0 10 0.0 1.0 |
| Regulation of runx1 expression and activity 0 17 0.0 1.0 |
| Gaba synthesis release reuptake and degradation 0 12 0.0 1.0 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0 17 0.0 1.0 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0 7 0.0 1.0 |
| Activation of the tfap2 ap 2 family of transcription factors 0 8 0.0 1.0 |
| Negative regulation of activity of tfap2 ap 2 family transcription factors 0 7 0.0 1.0 |
| E3 ubiquitin ligases ubiquitinate target proteins 0 40 0.0 1.0 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 0 26 0.0 1.0 |
| Vldlr internalisation and degradation 0 9 0.0 1.0 |
| Vldl assembly 0 3 0.0 1.0 |
| Reelin signalling pathway 0 3 0.0 1.0 |
| Met activates ptpn11 0 5 0.0 1.0 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0 27 0.0 1.0 |
| Downregulation of erbb2 signaling 0 18 0.0 1.0 |
| Ptk6 promotes hif1a stabilization 0 2 0.0 1.0 |
| Golgi to er retrograde transport 1 115 0.3521661296097386 0.9406708107542278 |
| Interleukin 20 family signaling 0 11 0.0 1.0 |
| Aurka activation by tpx2 3 73 1.7425044091710755 0.2579811764447431 |
| Tbc rabgaps 0 39 0.0 1.0 |
| Transcriptional regulation by ventx 0 37 0.0 1.0 |
| Tfap2 ap 2 family regulates transcription of cell cycle factors 0 5 0.0 1.0 |
| Signaling by fgfr3 fusions in cancer 0 10 0.0 1.0 |
| Sensory processing of sound by outer hair cells of the cochlea 0 25 0.0 1.0 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0 5 0.0 1.0 |
| Signaling by mras complex mutants 0 8 0.0 1.0 |
| Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 0 3 0.0 1.0 |
| Protein methylation 0 16 0.0 1.0 |
| Inla mediated entry of listeria monocytogenes into host cells 0 9 0.0 1.0 |
| Adora2b mediated anti inflammatory cytokines production 0 30 0.0 1.0 |
| Purinergic signaling in leishmaniasis infection 1 12 3.687940630797774 0.2541534411772372 |
| Listeria monocytogenes entry into host cells 0 21 0.0 1.0 |
| Rab gefs exchange gtp for gdp on rabs 0 79 0.0 1.0 |
| Met promotes cell motility 1 29 1.4463556851311954 0.5079876539292768 |
| Met receptor recycling 0 10 0.0 1.0 |
| Met activates rap1 and rac1 0 11 0.0 1.0 |
| Met interacts with tns proteins 0 4 0.0 1.0 |
| Inlb mediated entry of listeria monocytogenes into host cell 0 15 0.0 1.0 |
| Creb3 factors activate genes 0 3 0.0 1.0 |
| Defective factor viii causes hemophilia a 0 3 0.0 1.0 |
| Met activates ptk2 signaling 1 19 2.2521541950113377 0.3715199079432311 |
| Rab geranylgeranylation 0 54 0.0 1.0 |
| Rrna processing in the mitochondrion 0 10 0.0 1.0 |
| Dna repair 6 291 0.8478070175438597 0.7088031756079225 |
| Interleukin 6 signaling 0 8 0.0 1.0 |
| Caspase activation via extrinsic apoptotic signalling pathway 0 18 0.0 1.0 |
| Nef mediated cd8 down regulation 0 6 0.0 1.0 |
| Acetylcholine binding and downstream events 0 2 0.0 1.0 |
| Norepinephrine neurotransmitter release cycle 0 12 0.0 1.0 |
| Serotonin neurotransmitter release cycle 0 14 0.0 1.0 |
| Rip mediated nfkb activation via zbp1 0 16 0.0 1.0 |
| Extension of telomeres 1 52 0.7922368947579032 0.7200709140128994 |
| Nuclear import of rev protein 1 34 1.2265924551638838 0.5647101544543685 |
| Apobec3g mediated resistance to hiv 1 infection 0 4 0.0 1.0 |
| Egfr downregulation 0 22 0.0 1.0 |
| Shc1 events in egfr signaling 0 7 0.0 1.0 |
| Darpp 32 events 0 20 0.0 1.0 |
| Srp dependent cotranslational protein targeting to membrane 0 108 0.0 1.0 |
| Apc cdc20 mediated degradation of nek2a 0 25 0.0 1.0 |
| Chondroitin sulfate dermatan sulfate metabolism 0 32 0.0 1.0 |
| Signaling by egfr 1 40 1.037257980115123 0.6242434222626774 |
| Retrograde neurotrophin signalling 0 12 0.0 1.0 |
| Interactions of rev with host cellular proteins 1 37 1.1240362811791382 0.5955662992954859 |
| Unwinding of dna 0 12 0.0 1.0 |
| Gab1 signalosome 0 10 0.0 1.0 |
| Cytosolic sensors of pathogen associated dna 3 56 2.305380852550664 0.1524764865133537 |
| Signaling by cytosolic fgfr1 fusion mutants 0 18 0.0 1.0 |
| Fgfr1 mutant receptor activation 0 22 0.0 1.0 |
| Fgfr1b ligand binding and activation 0 2 0.0 1.0 |
| Fgfr1 ligand binding and activation 0 2 0.0 1.0 |
| Fgfr2 ligand binding and activation 0 2 0.0 1.0 |
| Fgfr3 ligand binding and activation 0 3 0.0 1.0 |
| Signaling by fgfr 0 57 0.0 1.0 |
| Heme degradation 1 7 6.764625850340136 0.1571881112173651 |
| Heme biosynthesis 1 12 3.687940630797774 0.2541534411772372 |
| Cellular hexose transport 0 6 0.0 1.0 |
| Signalling to p38 via rit and rin 0 3 0.0 1.0 |
| Signalling to erks 0 30 0.0 1.0 |
| Ngf independant trka activation 0 1 0.0 1.0 |
| Activation of trka receptors 0 1 0.0 1.0 |
| Signaling by pdgf 0 35 0.0 1.0 |
| Downstream signal transduction 0 23 0.0 1.0 |
| Regulation of beta cell development 1 22 1.9298347910592808 0.4160065505344545 |
| Synthesis of ip3 and ip4 in the cytosol 0 20 0.0 1.0 |
| Synthesis of ip2 ip and ins in the cytosol 0 12 0.0 1.0 |
| Synthesis of pyrophosphates in the cytosol 0 10 0.0 1.0 |
| Fgfr2 mutant receptor activation 0 18 0.0 1.0 |
| Phosphorylation of emi1 0 6 0.0 1.0 |
| Phosphorylation of the apc c 0 20 0.0 1.0 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0 20 0.0 1.0 |
| Activation of atr in response to replication stress 0 38 0.0 1.0 |
| Neurotoxicity of clostridium toxins 1 8 5.797667638483965 0.1775366954381628 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 1 42 0.986460925833748 0.6422270888991375 |
| Nod1 2 signaling pathway 0 30 0.0 1.0 |
| Viral messenger rna synthesis 1 44 0.9403891789273848 0.6593533907576883 |
| Ns1 mediated effects on host pathways 1 40 1.037257980115123 0.6242434222626774 |
| Export of viral ribonucleoproteins from nucleus 1 32 1.3059907834101383 0.5428479192551358 |
| Influenza infection 1 150 0.2684837693466648 0.9750481923531418 |
| Toll like receptor tlr1 tlr2 cascade 1 70 0.5845016267376516 0.8201241756611954 |
| Toll like receptor 9 tlr9 cascade 1 75 0.5447324875896304 0.8409413753361634 |
| Trafficking and processing of endosomal tlr 0 8 0.0 1.0 |
| The fatty acid cycling model 0 1 0.0 1.0 |
| Nef mediated cd4 down regulation 0 7 0.0 1.0 |
| Hiv elongation arrest and recovery 0 32 0.0 1.0 |
| Abortive elongation of hiv 1 transcript in the absence of tat 0 23 0.0 1.0 |
| Transcription of the hiv genome 0 67 0.0 1.0 |
| Hiv transcription elongation 0 42 0.0 1.0 |
| Hiv transcription initiation 0 45 0.0 1.0 |
| Signalling to ras 0 16 0.0 1.0 |
| Terminal pathway of complement 0 1 0.0 1.0 |
| Toll like receptor cascades 1 103 0.394077631052421 0.9202123929453974 |
| Fgfr3b ligand binding and activation 0 1 0.0 1.0 |
| Ticam1 rip1 mediated ikk complex recruitment 0 16 0.0 1.0 |
| Prolonged erk activation events 0 12 0.0 1.0 |
| Interactions of vpr with host cellular proteins 1 37 1.1240362811791382 0.5955662992954859 |
| Assembly of the hiv virion 0 15 0.0 1.0 |
| Plasma lipoprotein assembly remodeling and clearance 1 40 1.037257980115123 0.6242434222626774 |
| Activation of c3 and c5 0 1 0.0 1.0 |
| Telomere c strand synthesis initiation 0 13 0.0 1.0 |
| Telomere c strand lagging strand synthesis 1 37 1.1240362811791382 0.5955662992954859 |
| Processive synthesis on the c strand of the telomere 0 21 0.0 1.0 |
| Polymerase switching on the c strand of the telomere 1 28 1.5000755857898715 0.4957890007184933 |
| Glutathione synthesis and recycling 0 8 0.0 1.0 |
| Transport and synthesis of paps 0 4 0.0 1.0 |
| Apc c cdc20 mediated degradation of cyclin b 0 23 0.0 1.0 |
| Alternative complement activation 0 1 0.0 1.0 |
| Telomere extension by telomerase 0 21 0.0 1.0 |
| P38mapk events 0 13 0.0 1.0 |
| Arms mediated activation 0 5 0.0 1.0 |
| Signaling by tgf beta receptor complex 1 67 0.6112554112554113 0.8063536449390534 |
| Regulation of glucokinase by glucokinase regulatory protein 1 31 1.349659863945578 0.5315101420828222 |
| Adenylate cyclase inhibitory pathway 0 6 0.0 1.0 |
| Adenylate cyclase activating pathway 0 3 0.0 1.0 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 1 57 0.7211370262390671 0.7524126639072135 |
| Fgfr1c ligand binding and activation 0 2 0.0 1.0 |
| Fgfr2c ligand binding and activation 0 2 0.0 1.0 |
| Fgfr2b ligand binding and activation 0 2 0.0 1.0 |
| Cs ds degradation 0 7 0.0 1.0 |
| Hs gag biosynthesis 0 17 0.0 1.0 |
| Dermatan sulfate biosynthesis 0 6 0.0 1.0 |
| Chondroitin sulfate biosynthesis 0 12 0.0 1.0 |
| Keratan sulfate degradation 1 6 8.118367346938776 0.1363381791325428 |
| Metabolism of angiotensinogen to angiotensins 0 8 0.0 1.0 |
| Assembly of collagen fibrils and other multimeric structures 0 28 0.0 1.0 |
| Metabolism of nitric oxide nos3 activation and regulation 0 10 0.0 1.0 |
| G protein activation 0 13 0.0 1.0 |
| Formation of the beta catenin tcf transactivating complex 0 38 0.0 1.0 |
| Wnt mediated activation of dvl 0 8 0.0 1.0 |
| Signaling by alk 0 19 0.0 1.0 |
| Signaling by bmp 0 15 0.0 1.0 |
| Membrane trafficking 14 532 1.0987884436160298 0.4080680546662839 |
| Er to golgi anterograde transport 1 129 0.3132015306122448 0.958027894079508 |
| Creb phosphorylation 0 7 0.0 1.0 |
| Negative regulation of the pi3k akt network 1 62 0.6616928738708598 0.7810312178815177 |
| Vitamin b5 pantothenate metabolism 0 13 0.0 1.0 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 1 26 1.620408163265306 0.4704807306772423 |
| Generation of second messenger molecules 0 11 0.0 1.0 |
| Erk mapk targets 0 20 0.0 1.0 |
| Calcineurin activates nfat 0 8 0.0 1.0 |
| Signaling by hippo 0 21 0.0 1.0 |
| Regulation of gene expression in early pancreatic precursor cells 0 3 0.0 1.0 |
| Regulation of gene expression in beta cells 0 12 0.0 1.0 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 1 10 4.508390022675737 0.2167775624926856 |
| Glutamate neurotransmitter release cycle 0 17 0.0 1.0 |
| Metabolism of amine derived hormones 0 1 0.0 1.0 |
| Nf kb is activated and signals survival 0 11 0.0 1.0 |
| P75ntr recruits signalling complexes 0 11 0.0 1.0 |
| Nrif signals cell death from the nucleus 0 14 0.0 1.0 |
| Nade modulates death signalling 0 5 0.0 1.0 |
| Cell death signalling via nrage nrif and nade 0 63 0.0 1.0 |
| Linoleic acid la metabolism 0 7 0.0 1.0 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 0 12 0.0 1.0 |
| Regulation of pyruvate dehydrogenase pdh complex 0 16 0.0 1.0 |
| Copii mediated vesicle transport 1 55 0.7479969765684051 0.7399484418736413 |
| Microrna mirna biogenesis 0 24 0.0 1.0 |
| Nostrin mediated enos trafficking 0 3 0.0 1.0 |
| Enos activation 0 7 0.0 1.0 |
| Yap1 and wwtr1 taz stimulated gene expression 0 10 0.0 1.0 |
| Fcgr activation 0 5 0.0 1.0 |
| Erks are inactivated 0 11 0.0 1.0 |
| Initial triggering of complement 0 1 0.0 1.0 |
| Nuclear events kinase and transcription factor activation 0 42 0.0 1.0 |
| Akt phosphorylates targets in the cytosol 0 14 0.0 1.0 |
| Signaling by vegf 3 87 1.450029394473839 0.3505166983265811 |
| Bile acid and bile salt metabolism 1 22 1.9298347910592808 0.4160065505344545 |
| Synthesis of bile acids and bile salts via 27 hydroxycholesterol 0 7 0.0 1.0 |
| Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0 5 0.0 1.0 |
| P75 ntr receptor mediated signalling 1 81 0.5035714285714286 0.8627781534140635 |
| P75ntr regulates axonogenesis 0 5 0.0 1.0 |
| Regulated proteolysis of p75ntr 1 11 4.057142857142857 0.2356930071839008 |
| P75ntr negatively regulates cell cycle via sc1 0 5 0.0 1.0 |
| Nrage signals death through jnk 0 47 0.0 1.0 |
| P75ntr signals via nf kb 0 14 0.0 1.0 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0 13 0.0 1.0 |
| Estrogen biosynthesis 0 2 0.0 1.0 |
| Androgen biosynthesis 0 2 0.0 1.0 |
| Synthesis of bile acids and bile salts 1 20 2.133404940923738 0.3867116248199588 |
| Snrnp assembly 1 53 0.7769230769230769 0.726859415108312 |
| Pre notch processing in the endoplasmic reticulum 0 5 0.0 1.0 |
| Gap junction degradation 0 12 0.0 1.0 |
| Transport of connexons to the plasma membrane 0 14 0.0 1.0 |
| Gap junction assembly 0 15 0.0 1.0 |
| Vegf ligand receptor interactions 0 2 0.0 1.0 |
| Akt phosphorylates targets in the nucleus 0 9 0.0 1.0 |
| Rho gtpase effectors 8 246 1.3716545441706094 0.2435286120595283 |
| Metabolism of steroid hormones 0 12 0.0 1.0 |
| Pi3k akt activation 0 7 0.0 1.0 |
| Signaling by notch2 0 22 0.0 1.0 |
| Signaling by notch1 2 56 1.5021250758955678 0.3929907866903629 |
| Nicotinamide salvaging 1 11 4.057142857142857 0.2356930071839008 |
| A tetrasaccharide linker sequence is required for gag synthesis 0 16 0.0 1.0 |
| Metabolism of vitamins and cofactors 5 134 1.5794975714883075 0.2226406444315481 |
| Metabolism of water soluble vitamins and cofactors 4 91 1.873848199867009 0.1770898669719441 |
| Vitamin b2 riboflavin metabolism 0 4 0.0 1.0 |
| Vitamin c ascorbate metabolism 0 6 0.0 1.0 |
| Vitamin b1 thiamin metabolism 0 5 0.0 1.0 |
| Nicotinate metabolism 1 18 2.384873949579832 0.3559534457378639 |
| Vitamin d calciferol metabolism 0 8 0.0 1.0 |
| Coenzyme a biosynthesis 0 8 0.0 1.0 |
| Biotin transport and metabolism 0 11 0.0 1.0 |
| Metabolism of folate and pterines 1 15 2.896793002915452 0.3069124011154697 |
| Pi3k events in erbb2 signaling 0 7 0.0 1.0 |
| Grb2 events in erbb2 signaling 0 7 0.0 1.0 |
| Beta catenin phosphorylation cascade 0 16 0.0 1.0 |
| Pregnenolone biosynthesis 0 8 0.0 1.0 |
| Signaling by wnt 6 213 1.1766908212560387 0.4089277710544549 |
| Complement cascade 0 10 0.0 1.0 |
| Signaling by ntrks 0 102 0.0 1.0 |
| The activation of arylsulfatases 1 8 5.797667638483965 0.1775366954381628 |
| Downregulation of erbb4 signaling 0 7 0.0 1.0 |
| Nuclear signaling by erbb4 1 18 2.384873949579832 0.3559534457378639 |
| Shc1 events in erbb4 signaling 0 6 0.0 1.0 |
| Pi3k events in erbb4 signaling 0 2 0.0 1.0 |
| Shc1 events in erbb2 signaling 0 13 0.0 1.0 |
| Erythrocytes take up oxygen and release carbon dioxide 0 1 0.0 1.0 |
| Methionine salvage pathway 1 6 8.118367346938776 0.1363381791325428 |
| Erythrocytes take up carbon dioxide and release oxygen 0 4 0.0 1.0 |
| Cross presentation of particulate exogenous antigens phagosomes 0 3 0.0 1.0 |
| Signaling by erbb4 1 36 1.156268221574344 0.5855309260576435 |
| Constitutive signaling by ligand responsive egfr cancer variants 0 17 0.0 1.0 |
| Regulation of gene expression by hypoxia inducible factor 0 5 0.0 1.0 |
| Signaling by erbb2 in cancer 0 17 0.0 1.0 |
| Signaling by erbb2 0 37 0.0 1.0 |
| Signaling by fgfr in disease 0 48 0.0 1.0 |
| Meiotic synapsis 1 31 1.349659863945578 0.5315101420828222 |
| Signaling by nodal 0 12 0.0 1.0 |
| Prolactin receptor signaling 0 9 0.0 1.0 |
| Antiviral mechanism by ifn stimulated genes 1 73 0.5599773242630386 0.8329191570462157 |
| Interleukin 7 signaling 0 13 0.0 1.0 |
| Activation of ras in b cells 0 3 0.0 1.0 |
| Developmental biology 14 665 0.8619762699295513 0.7404082427400207 |
| Spry regulation of fgf signaling 0 14 0.0 1.0 |
| Extrinsic pathway of fibrin clot formation 0 1 0.0 1.0 |
| Caspase activation via death receptors in the presence of ligand 0 11 0.0 1.0 |
| Apoptosis induced dna fragmentation 0 11 0.0 1.0 |
| Activation of puma and translocation to mitochondria 0 8 0.0 1.0 |
| Elevation of cytosolic ca2 levels 0 6 0.0 1.0 |
| Abc transporters in lipid homeostasis 0 7 0.0 1.0 |
| Bmal1 clock npas2 activates circadian gene expression 1 20 2.133404940923738 0.3867116248199588 |
| Rora activates gene expression 0 17 0.0 1.0 |
| Mitochondrial iron sulfur cluster biogenesis 0 12 0.0 1.0 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0 16 0.0 1.0 |
| Transcription of e2f targets under negative control by dream complex 0 19 0.0 1.0 |
| Downregulation of erbb2 erbb3 signaling 0 10 0.0 1.0 |
| Grb7 events in erbb2 signaling 0 2 0.0 1.0 |
| Acrosome reaction and sperm oocyte membrane binding 0 1 0.0 1.0 |
| Sperm motility and taxes 0 1 0.0 1.0 |
| Tandem pore domain potassium channels 0 2 0.0 1.0 |
| Voltage gated potassium channels 0 2 0.0 1.0 |
| Potassium channels 0 15 0.0 1.0 |
| Inwardly rectifying k channels 0 12 0.0 1.0 |
| Adaptive immune system 16 504 1.348823948681397 0.1592672753763542 |
| Intrinsic pathway of fibrin clot formation 1 7 6.764625850340136 0.1571881112173651 |
| Gpvi mediated activation cascade 1 21 2.026530612244898 0.4015375820029667 |
| Effects of pip2 hydrolysis 0 17 0.0 1.0 |
| Smac xiap regulated apoptotic response 0 8 0.0 1.0 |
| Apoptotic cleavage of cellular proteins 2 35 2.4632389468455043 0.2064377407436189 |
| Cytochrome c mediated apoptotic response 0 13 0.0 1.0 |
| Activation of caspases through apoptosome mediated cleavage 0 6 0.0 1.0 |
| Formation of apoptosome 0 11 0.0 1.0 |
| Release of apoptotic factors from the mitochondria 0 6 0.0 1.0 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0 8 0.0 1.0 |
| Activation of noxa and translocation to mitochondria 0 5 0.0 1.0 |
| Activation of bad and translocation to mitochondria 0 16 0.0 1.0 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 1 28 1.5000755857898715 0.4957890007184933 |
| Polb dependent long patch base excision repair 0 9 0.0 1.0 |
| Displacement of dna glycosylase by apex1 0 8 0.0 1.0 |
| Recognition and association of dna glycosylase with site containing an affected purine 0 16 0.0 1.0 |
| Translesion synthesis by polh 1 20 2.133404940923738 0.3867116248199588 |
| Recognition of dna damage by pcna containing replication complex 1 30 1.3963406052076002 0.5198923492291299 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 1 41 1.0112244897959184 0.6333450487016228 |
| Mapk3 erk1 activation 0 8 0.0 1.0 |
| Intrinsic pathway for apoptosis 0 53 0.0 1.0 |
| Hemostasis 12 361 1.4107707001689809 0.1634379763842546 |
| Apoptotic factor mediated response 0 20 0.0 1.0 |
| Disinhibition of snare formation 0 4 0.0 1.0 |
| Opioid signalling 2 63 1.3288094598226283 0.4514760703959606 |
| Camk iv mediated phosphorylation of creb 1 8 5.797667638483965 0.1775366954381628 |
| Activation of bh3 only proteins 0 29 0.0 1.0 |
| E2f mediated regulation of dna replication 0 23 0.0 1.0 |
| E2f enabled inhibition of pre replication complex formation 0 10 0.0 1.0 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 0 13 0.0 1.0 |
| Formation of the early elongation complex 0 33 0.0 1.0 |
| Sos mediated signalling 0 7 0.0 1.0 |
| Mapk1 erk2 activation 0 7 0.0 1.0 |
| Raf independent mapk1 3 activation 0 15 0.0 1.0 |
| Irs mediated signalling 0 26 0.0 1.0 |
| Formation of rna pol ii elongation complex 0 58 0.0 1.0 |
| Neuronal system 5 177 1.1794364566245297 0.4249089086626467 |
| Transmission across chemical synapses 3 139 0.8908859840232389 0.6563003006015532 |
| Neurotransmitter receptors and postsynaptic signal transmission 3 105 1.1919632050351006 0.4670496335734261 |
| Neurotransmitter clearance 0 3 0.0 1.0 |
| Neurotransmitter release cycle 0 30 0.0 1.0 |
| Presynaptic depolarization and calcium channel opening 0 4 0.0 1.0 |
| Electric transmission across gap junctions 0 2 0.0 1.0 |
| G protein mediated events 2 40 2.1380500431406384 0.2511786735203468 |
| Ca dependent events 1 26 1.620408163265306 0.4704807306772423 |
| Pka mediated phosphorylation of creb 0 13 0.0 1.0 |
| Pecam1 interactions 0 9 0.0 1.0 |
| Common pathway of fibrin clot formation 0 5 0.0 1.0 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0 21 0.0 1.0 |
| Integration of energy metabolism 1 71 0.5760932944606414 0.8244940603927083 |
| Ampk inhibits chrebp transcriptional activation activity 0 7 0.0 1.0 |
| Triglyceride catabolism 0 13 0.0 1.0 |
| Glucagon signaling in metabolic regulation 0 21 0.0 1.0 |
| Pka mediated phosphorylation of key metabolic factors 0 4 0.0 1.0 |
| Post translational modification synthesis of gpi anchored proteins 0 32 0.0 1.0 |
| Hiv infection 8 213 1.5978684156589464 0.1435788052605031 |
| Attachment of gpi anchor to upar 0 7 0.0 1.0 |
| Synthesis of glycosylphosphatidylinositol gpi 0 12 0.0 1.0 |
| Golgi cisternae pericentriolar stack reorganization 0 14 0.0 1.0 |
| Early phase of hiv life cycle 1 13 3.380272108843537 0.2721697661507766 |
| Integration of provirus 1 9 5.072448979591837 0.1973959389561772 |
| Budding and maturation of hiv virion 0 27 0.0 1.0 |
| Hiv life cycle 2 144 0.5661510043869776 0.8664690810483541 |
| Degradation of cysteine and homocysteine 1 12 3.687940630797774 0.2541534411772372 |
| Sulfide oxidation to sulfate 0 5 0.0 1.0 |
| Irf3 mediated activation of type 1 ifn 0 3 0.0 1.0 |
| Zbp1 dai mediated induction of type i ifns 0 18 0.0 1.0 |
| Gamma carboxylation transport and amino terminal cleavage of proteins 0 5 0.0 1.0 |
| Chrebp activates metabolic gene expression 0 8 0.0 1.0 |
| Removal of aminoterminal propeptides from gamma carboxylated proteins 0 4 0.0 1.0 |
| Pp2a mediated dephosphorylation of key metabolic factors 0 6 0.0 1.0 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 1 29 1.4463556851311954 0.5079876539292768 |
| Mtorc1 mediated signalling 0 23 0.0 1.0 |
| Mitochondrial uncoupling 0 1 0.0 1.0 |
| Myd88 independent tlr4 cascade 1 78 0.5233501192684866 0.8522610344387342 |
| Sphingolipid de novo biosynthesis 2 29 3.012446873102611 0.154226710893935 |
| Synthesis of pips at the late endosome membrane 0 10 0.0 1.0 |
| Synthesis of pips at the early endosome membrane 0 16 0.0 1.0 |
| Synthesis of pips at the golgi membrane 0 15 0.0 1.0 |
| Synthesis of pips at the plasma membrane 0 47 0.0 1.0 |
| Regulation of cholesterol biosynthesis by srebp srebf 2 55 1.5306217135787197 0.3844009902554037 |
| Mtor signalling 0 39 0.0 1.0 |
| Collagen biosynthesis and modifying enzymes 0 30 0.0 1.0 |
| The role of nef in hiv 1 replication and disease pathogenesis 0 20 0.0 1.0 |
| Nef and signal transduction 0 4 0.0 1.0 |
| Nef mediated downregulation of mhc class i complex cell surface expression 0 9 0.0 1.0 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0 16 0.0 1.0 |
| 2 ltr circle formation 1 7 6.764625850340136 0.1571881112173651 |
| Pka activation in glucagon signalling 0 12 0.0 1.0 |
| Signaling by egfr in cancer 0 17 0.0 1.0 |
| Cell cycle 19 613 1.3183523932422612 0.1565077964337919 |
| Heparan sulfate heparin hs gag metabolism 2 32 2.710382513661202 0.1800390494619342 |
| Formation of fibrin clot clotting cascade 1 9 5.072448979591837 0.1973959389561772 |
| Recycling of bile acids and salts 0 6 0.0 1.0 |
| Transport of mature mrnas derived from intronless transcripts 2 43 1.9810075969612155 0.2781824052676386 |
| Acyl chain remodelling of pi 0 4 0.0 1.0 |
| Acyl chain remodeling of dag and tag 0 2 0.0 1.0 |
| Acyl chain remodelling of pe 0 8 0.0 1.0 |
| Acyl chain remodelling of ps 0 9 0.0 1.0 |
| Acyl chain remodeling of cl 0 5 0.0 1.0 |
| Acyl chain remodelling of pc 0 9 0.0 1.0 |
| Reversible hydration of carbon dioxide 0 2 0.0 1.0 |
| Collagen formation 0 44 0.0 1.0 |
| Extracellular matrix organization 4 131 1.278453829634932 0.389337546672897 |
| Degradation of the extracellular matrix 3 56 2.305380852550664 0.1524764865133537 |
| Reproduction 2 57 1.4746646795827123 0.4015263058449369 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0 7 0.0 1.0 |
| Alpha defensins 0 1 0.0 1.0 |
| Defensins 0 1 0.0 1.0 |
| Translocation of slc2a4 glut4 to the plasma membrane 1 66 0.6207221350078493 0.8015340371466311 |
| Collagen degradation 1 21 2.026530612244898 0.4015375820029667 |
| Regulation of signaling by nodal 0 3 0.0 1.0 |
| Regulation of kit signaling 0 12 0.0 1.0 |
| Signaling by scf kit 0 31 0.0 1.0 |
| Acyl chain remodelling of pg 0 7 0.0 1.0 |
| Activation of matrix metalloproteinases 0 6 0.0 1.0 |
| Synthesis of pi 0 5 0.0 1.0 |
| Inositol phosphate metabolism 0 40 0.0 1.0 |
| Transport of the slbp dependant mature mrna 1 36 1.156268221574344 0.5855309260576435 |
| Metabolism of nucleotides 4 82 2.0919686374231827 0.1360002203186876 |
| Gap junction trafficking and regulation 0 28 0.0 1.0 |
| Telomere maintenance 1 74 0.5522504892367907 0.8369794047452616 |
| Eukaryotic translation elongation 0 89 0.0 1.0 |
| Polo like kinase mediated events 0 16 0.0 1.0 |
| Fibronectin matrix formation 0 3 0.0 1.0 |
| Elastic fibre formation 0 23 0.0 1.0 |
| Glutathione conjugation 0 21 0.0 1.0 |
| Glucuronidation 0 4 0.0 1.0 |
| Cytosolic sulfonation of small molecules 1 14 3.119937205651492 0.2897526236095206 |
| Methylation 0 12 0.0 1.0 |
| Phase ii conjugation of compounds 2 53 1.5909675345548056 0.3670688568616856 |
| G0 and early g1 0 26 0.0 1.0 |
| Signaling by activin 0 9 0.0 1.0 |
| Cell cell communication 1 79 0.5165881737310308 0.8558530274917338 |
| Meiosis 1 54 0.762187139006546 0.7334839427632852 |
| Dag and ip3 signaling 2 30 2.9045667447306798 0.1627514901813832 |
| Pi metabolism 0 71 0.0 1.0 |
| Synthesis of pips at the er membrane 0 5 0.0 1.0 |
| Tnfr1 induced proapoptotic signaling 0 13 0.0 1.0 |
| Tie2 signaling 0 12 0.0 1.0 |
| Cytochrome p450 arranged by substrate type 1 15 2.896793002915452 0.3069124011154697 |
| Synthesis secretion and deacylation of ghrelin 0 5 0.0 1.0 |
| Cell cell junction organization 1 31 1.349659863945578 0.5315101420828222 |
| Nectin necl trans heterodimerization 0 5 0.0 1.0 |
| Glucagon type ligand receptors 0 13 0.0 1.0 |
| Tight junction interactions 1 11 4.057142857142857 0.2356930071839008 |
| Lysosphingolipid and lpa receptors 0 3 0.0 1.0 |
| Ncam1 interactions 0 15 0.0 1.0 |
| Adherens junctions interactions 0 18 0.0 1.0 |
| Regulation of insulin secretion 1 48 0.8600086843247937 0.6911948368646196 |
| Role of second messengers in netrin 1 signaling 0 3 0.0 1.0 |
| Netrin mediated repulsion signals 0 5 0.0 1.0 |
| Dcc mediated attractive signaling 1 13 3.380272108843537 0.2721697661507766 |
| G alpha z signalling events 0 28 0.0 1.0 |
| Adp signalling through p2y purinoceptor 1 0 17 0.0 1.0 |
| G alpha s signalling events 0 37 0.0 1.0 |
| Cgmp effects 0 7 0.0 1.0 |
| Platelet calcium homeostasis 1 13 3.380272108843537 0.2721697661507766 |
| Reduction of cytosolic ca levels 1 7 6.764625850340136 0.1571881112173651 |
| Caspase activation via dependence receptors in the absence of ligand 0 7 0.0 1.0 |
| Transport of bile salts and organic acids metal ions and amine compounds 1 32 1.3059907834101383 0.5428479192551358 |
| Bicarbonate transporters 0 4 0.0 1.0 |
| Transport of inorganic cations anions and amino acids oligopeptides 2 44 1.9336455893832944 0.2871762535363917 |
| Deadenylation dependent mrna decay 2 57 1.4746646795827123 0.4015263058449369 |
| Thromboxane signalling through tp receptor 0 15 0.0 1.0 |
| Role of abl in robo slit signaling 0 9 0.0 1.0 |
| Organic anion transporters 0 3 0.0 1.0 |
| Inactivation of cdc42 and rac1 0 8 0.0 1.0 |
| Regulation of commissural axon pathfinding by slit and robo 0 7 0.0 1.0 |
| Activation of rac1 0 12 0.0 1.0 |
| Sodium coupled phosphate cotransporters 0 2 0.0 1.0 |
| Multifunctional anion exchangers 0 3 0.0 1.0 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0 27 0.0 1.0 |
| Sirt1 negatively regulates rrna expression 0 18 0.0 1.0 |
| Small interfering rna sirna biogenesis 0 9 0.0 1.0 |
| Cation coupled chloride cotransporters 0 4 0.0 1.0 |
| Arachidonate production from dag 0 4 0.0 1.0 |
| Sodium proton exchangers 0 4 0.0 1.0 |
| Sodium calcium exchangers 0 3 0.0 1.0 |
| Metal ion slc transporters 0 15 0.0 1.0 |
| Slc mediated transmembrane transport 3 101 1.2411186696900982 0.4418071915292876 |
| Transport of vitamins nucleosides and related molecules 0 21 0.0 1.0 |
| Platelet homeostasis 1 51 0.8081632653061225 0.713114397687874 |
| Nucleotide like purinergic receptors 0 1 0.0 1.0 |
| P2y receptors 0 1 0.0 1.0 |
| Trafficking of glur2 containing ampa receptors 0 11 0.0 1.0 |
| Epha mediated growth cone collapse 1 23 1.8419294990723565 0.4301270919610729 |
| Ephb mediated forward signaling 0 40 0.0 1.0 |
| Prostacyclin signalling through prostacyclin receptor 0 12 0.0 1.0 |
| Signal amplification 0 22 0.0 1.0 |
| Rap1 signalling 0 13 0.0 1.0 |
| G beta gamma signalling through pi3kgamma 0 15 0.0 1.0 |
| Adp signalling through p2y purinoceptor 12 0 13 0.0 1.0 |
| Nitric oxide stimulates guanylate cyclase 0 11 0.0 1.0 |
| Protein folding 0 79 0.0 1.0 |
| Signal regulatory protein family interactions 0 9 0.0 1.0 |
| Peroxisomal lipid metabolism 1 24 1.7616681455190772 0.4439075633632242 |
| Diseases associated with o glycosylation of proteins 1 17 2.534183673469388 0.3400030327298383 |
| Association of tric cct with target proteins during biosynthesis 0 36 0.0 1.0 |
| Folding of actin by cct tric 0 10 0.0 1.0 |
| Beta oxidation of very long chain fatty acids 0 9 0.0 1.0 |
| Post chaperonin tubulin folding pathway 0 18 0.0 1.0 |
| Formation of tubulin folding intermediates by cct tric 0 21 0.0 1.0 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 0 28 0.0 1.0 |
| Pd 1 signaling 0 5 0.0 1.0 |
| Ephrin signaling 0 17 0.0 1.0 |
| Deadenylation of mrna 1 26 1.620408163265306 0.4704807306772423 |
| Eph ephrin mediated repulsion of cells 0 43 0.0 1.0 |
| Trafficking of ampa receptors 1 20 2.133404940923738 0.3867116248199588 |
| Other semaphorin interactions 0 7 0.0 1.0 |
| Sema4d induced cell migration and growth cone collapse 1 18 2.384873949579832 0.3559534457378639 |
| Sema4d mediated inhibition of cell attachment and migration 0 8 0.0 1.0 |
| G alpha 12 13 signalling events 0 57 0.0 1.0 |
| G alpha q signalling events 1 66 0.6207221350078493 0.8015340371466311 |
| Sumoylation of intracellular receptors 0 18 0.0 1.0 |
| Ca2 pathway 0 45 0.0 1.0 |
| Sumoylation of sumoylation proteins 1 35 1.190396158463385 0.5752475783862557 |
| Sema4d in semaphorin signaling 1 23 1.8419294990723565 0.4301270919610729 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0 9 0.0 1.0 |
| Incretin synthesis secretion and inactivation 0 14 0.0 1.0 |
| Free fatty acids regulate insulin secretion 0 8 0.0 1.0 |
| Circadian clock 1 55 0.7479969765684051 0.7399484418736413 |
| Regulation of lipid metabolism by pparalpha 2 95 0.868764322228098 0.6723540440907236 |
| Adrenaline noradrenaline inhibits insulin secretion 0 16 0.0 1.0 |
| Acetylcholine regulates insulin secretion 0 8 0.0 1.0 |
| Crmps in sema3a signaling 0 12 0.0 1.0 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0 10 0.0 1.0 |
| Sema3a pak dependent axon repulsion 0 13 0.0 1.0 |
| G protein beta gamma signalling 0 22 0.0 1.0 |
| Mrna decay by 3 to 5 exoribonuclease 1 16 2.703401360544217 0.3236592382947187 |
| Mrna decay by 5 to 3 exoribonuclease 0 15 0.0 1.0 |
| Gp1b ix v activation signalling 0 7 0.0 1.0 |
| Defective c1galt1c1 causes tnps 0 2 0.0 1.0 |
| Defective lfng causes scdo3 0 3 0.0 1.0 |
| Defective galnt3 causes hftc 0 1 0.0 1.0 |
| Presynaptic function of kainate receptors 0 13 0.0 1.0 |
| Signaling by ctnnb1 phospho site mutants 0 15 0.0 1.0 |
| Signaling by wnt in cancer 0 25 0.0 1.0 |
| Sumoylation of immune response proteins 0 10 0.0 1.0 |
| Sumoylation of dna methylation proteins 0 16 0.0 1.0 |
| Repression of wnt target genes 0 13 0.0 1.0 |
| Regulation of fzd by ubiquitination 0 9 0.0 1.0 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 0 24 0.0 1.0 |
| Sumoylation of dna replication proteins 1 46 0.8984126984126984 0.6756630435254583 |
| Sumoylation of rna binding proteins 1 47 0.878793256433008 0.6835238209809511 |
| Thrombin signalling through proteinase activated receptors pars 0 21 0.0 1.0 |
| Sumoylation of chromatin organization proteins 1 58 0.7084138918725384 0.7584198129875613 |
| Mitotic g1 phase and g1 s transition 6 143 1.7906934306569342 0.1319695637736293 |
| Transcriptional regulation of pluripotent stem cells 0 16 0.0 1.0 |
| Interleukin 2 family signaling 0 21 0.0 1.0 |
| Ionotropic activity of kainate receptors 0 3 0.0 1.0 |
| Wnt5a dependent internalization of fzd4 0 13 0.0 1.0 |
| Ksrp khsrp binds and destabilizes mrna 1 17 2.534183673469388 0.3400030327298383 |
| Interleukin 3 interleukin 5 and gm csf signaling 0 31 0.0 1.0 |
| O linked glycosylation 1 35 1.190396158463385 0.5752475783862557 |
| Signaling by rnf43 mutants 0 4 0.0 1.0 |
| Signaling by lrp5 mutants 0 2 0.0 1.0 |
| Uptake and actions of bacterial toxins 1 23 1.8419294990723565 0.4301270919610729 |
| Uptake and function of diphtheria toxin 0 5 0.0 1.0 |
| Dna methylation 0 14 0.0 1.0 |
| N glycan trimming in the er and calnexin calreticulin cycle 1 32 1.3059907834101383 0.5428479192551358 |
| Diseases of immune system 0 15 0.0 1.0 |
| Myogenesis 0 22 0.0 1.0 |
| Negative epigenetic regulation of rrna expression 0 61 0.0 1.0 |
| B wich complex positively regulates rrna expression 0 45 0.0 1.0 |
| Positive epigenetic regulation of rrna expression 0 60 0.0 1.0 |
| Vegfr2 mediated cell proliferation 1 15 2.896793002915452 0.3069124011154697 |
| Vegfr2 mediated vascular permeability 0 22 0.0 1.0 |
| Regulated necrosis 1 42 0.986460925833748 0.6422270888991375 |
| Ripk1 mediated regulated necrosis 1 26 1.620408163265306 0.4704807306772423 |
| Uptake and function of anthrax toxins 0 10 0.0 1.0 |
| Pink1 prkn mediated mitophagy 1 17 2.534183673469388 0.3400030327298383 |
| Mitophagy 1 24 1.7616681455190772 0.4439075633632242 |
| O glycosylation of tsr domain containing proteins 0 5 0.0 1.0 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 0 12 0.0 1.0 |
| Sumoylation of transcription cofactors 0 41 0.0 1.0 |
| Hur elavl1 binds and stabilizes mrna 0 7 0.0 1.0 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 1 17 2.534183673469388 0.3400030327298383 |
| Smooth muscle contraction 2 28 3.128625472887768 0.1457934990596532 |
| Signal transduction by l1 0 20 0.0 1.0 |
| Interaction between l1 and ankyrins 0 12 0.0 1.0 |
| Rsk activation 0 7 0.0 1.0 |
| Activation of nmda receptors and postsynaptic events 3 68 1.8774928774928772 0.2256891642594976 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 1 7 6.764625850340136 0.1571881112173651 |
| Creb1 phosphorylation through the activation of adenylate cyclase 0 9 0.0 1.0 |
| Na cl dependent neurotransmitter transporters 0 4 0.0 1.0 |
| Zinc influx into cells by the slc39 gene family 0 7 0.0 1.0 |
| Depolymerisation of the nuclear lamina 0 16 0.0 1.0 |
| Binding of tcf lef ctnnb1 to target gene promoters 0 7 0.0 1.0 |
| Recycling pathway of l1 0 41 0.0 1.0 |
| Zinc efflux and compartmentalization by the slc30 family 0 5 0.0 1.0 |
| Zinc transporters 0 12 0.0 1.0 |
| Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0 6 0.0 1.0 |
| Lysosome vesicle biogenesis 2 32 2.710382513661202 0.1800390494619342 |
| Platelet sensitization by ldl 0 15 0.0 1.0 |
| Passive transport by aquaporins 0 1 0.0 1.0 |
| Vasopressin regulates renal water homeostasis via aquaporins 0 25 0.0 1.0 |
| Aquaporin mediated transport 0 26 0.0 1.0 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 1 17 2.534183673469388 0.3400030327298383 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 1 25 1.688095238095238 0.4573561220916043 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 2 59 1.422634454989934 0.4184251288308143 |
| Activation of the ap 1 family of transcription factors 0 8 0.0 1.0 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0 18 0.0 1.0 |
| Activated tak1 mediates p38 mapk activation 0 20 0.0 1.0 |
| Mapk targets nuclear events mediated by map kinases 0 27 0.0 1.0 |
| Other interleukin signaling 0 12 0.0 1.0 |
| Interleukin 1 processing 0 3 0.0 1.0 |
| Interleukin 17 signaling 0 57 0.0 1.0 |
| Interleukin 12 family signaling 2 43 1.9810075969612155 0.2781824052676386 |
| Neurofascin interactions 0 6 0.0 1.0 |
| Chl1 interactions 0 7 0.0 1.0 |
| Nrcam interactions 0 7 0.0 1.0 |
| Cell junction organization 1 54 0.762187139006546 0.7334839427632852 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0 7 0.0 1.0 |
| Cell extracellular matrix interactions 0 16 0.0 1.0 |
| Synthesis of substrates in n glycan biosythesis 2 44 1.9336455893832944 0.2871762535363917 |
| Synthesis of udp n acetyl glucosamine 0 8 0.0 1.0 |
| Synthesis of gdp mannose 0 5 0.0 1.0 |
| Asparagine n linked glycosylation 7 245 1.195175978341127 0.379011996473602 |
| Synthesis of dolichyl phosphate 0 5 0.0 1.0 |
| Type i hemidesmosome assembly 0 9 0.0 1.0 |
| Beta oxidation of pristanoyl coa 1 7 6.764625850340136 0.1571881112173651 |
| Glyoxylate metabolism and glycine degradation 1 22 1.9298347910592808 0.4160065505344545 |
| Alpha oxidation of phytanate 0 6 0.0 1.0 |
| Senescence associated secretory phenotype sasp 0 54 0.0 1.0 |
| Oxidative stress induced senescence 1 69 0.593157262905162 0.8156459393677341 |
| The phototransduction cascade 1 12 3.687940630797774 0.2541534411772372 |
| Condensation of prometaphase chromosomes 0 11 0.0 1.0 |
| Resolution of sister chromatid cohesion 5 120 1.774309940465452 0.16416111237839 |
| Activation of the phototransduction cascade 0 2 0.0 1.0 |
| Cohesin loading onto chromatin 1 10 4.508390022675737 0.2167775624926856 |
| Establishment of sister chromatid cohesion 1 11 4.057142857142857 0.2356930071839008 |
| Mastl facilitates mitotic progression 0 10 0.0 1.0 |
| The canonical retinoid cycle in rods twilight vision 0 4 0.0 1.0 |
| Retinoid cycle disease events 0 2 0.0 1.0 |
| Shc related events triggered by igf1r 0 7 0.0 1.0 |
| Activation of gene expression by srebf srebp 2 42 2.0307377049180326 0.2691814013824262 |
| Dap12 signaling 0 19 0.0 1.0 |
| Selenoamino acid metabolism 2 107 0.7685402029664324 0.7344217404793858 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 0 29 0.0 1.0 |
| Phosphate bond hydrolysis by nudt proteins 0 6 0.0 1.0 |
| Condensation of prophase chromosomes 0 23 0.0 1.0 |
| Crosslinking of collagen fibrils 0 10 0.0 1.0 |
| Cellular senescence 1 131 0.308320251177394 0.9600542146079176 |
| Constitutive signaling by aberrant pi3k in cancer 1 32 1.3059907834101383 0.5428479192551358 |
| Formation of senescence associated heterochromatin foci sahf 0 15 0.0 1.0 |
| Dna damage telomere stress induced senescence 0 38 0.0 1.0 |
| Nuclear envelope breakdown 1 54 0.762187139006546 0.7334839427632852 |
| Peptide hormone metabolism 0 43 0.0 1.0 |
| Notch2 activation and transmission of signal to the nucleus 0 16 0.0 1.0 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 0 8 0.0 1.0 |
| Pou5f1 oct4 sox2 nanog repress genes related to differentiation 0 6 0.0 1.0 |
| Fceri mediated ca 2 mobilization 1 20 2.133404940923738 0.3867116248199588 |
| Fceri mediated mapk activation 0 24 0.0 1.0 |
| Role of lat2 ntal lab on calcium mobilization 0 12 0.0 1.0 |
| Signaling by notch1 hd domain mutants in cancer 1 9 5.072448979591837 0.1973959389561772 |
| Eph ephrin signaling 1 80 0.5099974166881943 0.8593580344299 |
| Stimuli sensing channels 0 38 0.0 1.0 |
| Insulin processing 0 21 0.0 1.0 |
| Caspase mediated cleavage of cytoskeletal proteins 1 12 3.687940630797774 0.2541534411772372 |
| Acetylcholine neurotransmitter release cycle 0 11 0.0 1.0 |
| Fbxw7 mutants and notch1 in cancer 0 5 0.0 1.0 |
| Signaling by notch1 pest domain mutants in cancer 2 45 1.8884864658787648 0.2961580697833918 |
| Signaling by leptin 0 8 0.0 1.0 |
| Regulation of plk1 activity at g2 m transition 3 87 1.450029394473839 0.3505166983265811 |
| Trif mediated programmed cell death 0 4 0.0 1.0 |
| Oncogene induced senescence 0 30 0.0 1.0 |
| Activation of nima kinases nek9 nek6 nek7 0 7 0.0 1.0 |
| Pi3k akt signaling in cancer 1 58 0.7084138918725384 0.7584198129875613 |
| Notch2 intracellular domain regulates transcription 0 7 0.0 1.0 |
| Ubiquinol biosynthesis 0 7 0.0 1.0 |
| Synthesis of 15 eicosatetraenoic acid derivatives 0 3 0.0 1.0 |
| Synthesis of 12 eicosatetraenoic acid derivatives 0 2 0.0 1.0 |
| Synthesis of lipoxins lx 0 1 0.0 1.0 |
| Synthesis of leukotrienes lt and eoxins ex 0 4 0.0 1.0 |
| Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet 0 1 0.0 1.0 |
| Mhc class ii antigen presentation 2 100 0.8240214118434259 0.6995311108717109 |
| Molecules associated with elastic fibres 0 18 0.0 1.0 |
| Egfr interacts with phospholipase c gamma 0 2 0.0 1.0 |
| Dopamine neurotransmitter release cycle 0 18 0.0 1.0 |
| Prc2 methylates histones and dna 1 23 1.8419294990723565 0.4301270919610729 |
| Activated notch1 transmits signal to the nucleus 1 21 2.026530612244898 0.4015375820029667 |
| Notch1 intracellular domain regulates transcription 1 39 1.0646616541353384 0.6149168035506691 |
| Epigenetic regulation of gene expression 1 102 0.398019801980198 0.918219323141692 |
| Cyp2e1 reactions 0 1 0.0 1.0 |
| Xenobiotics 0 4 0.0 1.0 |
| Eicosanoids 0 1 0.0 1.0 |
| Endogenous sterols 1 12 3.687940630797774 0.2541534411772372 |
| Miscellaneous substrates 0 2 0.0 1.0 |
| Synthesis of 16 20 hydroxyeicosatetraenoic acids hete 0 1 0.0 1.0 |
| Anchoring fibril formation 0 8 0.0 1.0 |
| Hyaluronan metabolism 0 9 0.0 1.0 |
| Transcriptional activation of mitochondrial biogenesis 0 51 0.0 1.0 |
| Visual phototransduction 1 40 1.037257980115123 0.6242434222626774 |
| The retinoid cycle in cones daylight vision 0 1 0.0 1.0 |
| Egfr transactivation by gastrin 0 7 0.0 1.0 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 0 29 0.0 1.0 |
| Downregulation of smad2 3 smad4 transcriptional activity 1 23 1.8419294990723565 0.4301270919610729 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 1 41 1.0112244897959184 0.6333450487016228 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0 14 0.0 1.0 |
| Tgf beta receptor signaling activates smads 0 28 0.0 1.0 |
| Downregulation of tgf beta receptor signaling 0 22 0.0 1.0 |
| Binding and uptake of ligands by scavenger receptors 1 17 2.534183673469388 0.3400030327298383 |
| Dap12 interactions 0 21 0.0 1.0 |
| Scavenging of heme from plasma 0 2 0.0 1.0 |
| Synthesis of prostaglandins pg and thromboxanes tx 1 8 5.797667638483965 0.1775366954381628 |
| Abacavir metabolism 0 4 0.0 1.0 |
| Abacavir transport and metabolism 0 6 0.0 1.0 |
| Abacavir transmembrane transport 0 2 0.0 1.0 |
| Hyaluronan uptake and degradation 0 8 0.0 1.0 |
| Integrin cell surface interactions 0 37 0.0 1.0 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 0 8 0.0 1.0 |
| Hyaluronan biosynthesis and export 0 1 0.0 1.0 |
| Gene silencing by rna 2 75 1.109027621827981 0.5437935802005475 |
| Sumoylation 2 155 0.5248580306439515 0.8921604480272981 |
| Nuclear envelope ne reassembly 1 71 0.5760932944606414 0.8244940603927083 |
| Cytosolic trna aminoacylation 0 24 0.0 1.0 |
| Dopamine clearance from the synaptic cleft 0 2 0.0 1.0 |
| Myoclonic epilepsy of lafora 0 5 0.0 1.0 |
| Diseases associated with n glycosylation of proteins 1 18 2.384873949579832 0.3559534457378639 |
| Negative regulation of tcf dependent signaling by wnt ligand antagonists 0 5 0.0 1.0 |
| Deactivation of the beta catenin transactivating complex 0 36 0.0 1.0 |
| Signaling by robo receptors 6 197 1.2773560209424084 0.3397836997002576 |
| Dscam interactions 0 9 0.0 1.0 |
| Ncam signaling for neurite out growth 0 34 0.0 1.0 |
| L1cam interactions 1 91 0.4471655328798186 0.8927375563642727 |
| Semaphorin interactions 1 48 0.8600086843247937 0.6911948368646196 |
| Nephrin family interactions 0 17 0.0 1.0 |
| Netrin 1 signaling 1 33 1.2650510204081633 0.5539124029112868 |
| Class b 2 secretin family receptors 0 25 0.0 1.0 |
| Signaling by gpcr 6 204 1.2313131313131314 0.3699763259391625 |
| P130cas linkage to mapk signaling for integrins 0 9 0.0 1.0 |
| Transcriptional regulation by tp53 3 333 0.3598952487841377 0.9883396969977136 |
| Defective ext2 causes exostoses 2 0 11 0.0 1.0 |
| Defective chst6 causes mcdc1 0 1 0.0 1.0 |
| Trna aminoacylation 0 43 0.0 1.0 |
| Defective chsy1 causes tpbs 0 4 0.0 1.0 |
| Mitochondrial trna aminoacylation 0 23 0.0 1.0 |
| Recruitment of mitotic centrosome proteins and complexes 4 82 2.0919686374231827 0.1360002203186876 |
| Ctla4 inhibitory signaling 0 17 0.0 1.0 |
| Cd28 dependent vav1 pathway 0 7 0.0 1.0 |
| Cd28 dependent pi3k akt signaling 0 15 0.0 1.0 |
| Cd28 co stimulation 0 24 0.0 1.0 |
| Receptor type tyrosine protein phosphatases 1 11 4.057142857142857 0.2356930071839008 |
| Costimulation by the cd28 family 0 39 0.0 1.0 |
| Nuclear receptor transcription pathway 0 29 0.0 1.0 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0 12 0.0 1.0 |
| Olfactory signaling pathway 0 2 0.0 1.0 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 0 27 0.0 1.0 |
| Transcriptional regulation of white adipocyte differentiation 1 68 0.6020712762717028 0.8110566761636493 |
| Atf6 atf6 alpha activates chaperone genes 0 6 0.0 1.0 |
| Unfolded protein response upr 1 75 0.5447324875896304 0.8409413753361634 |
| Ire1alpha activates chaperones 0 44 0.0 1.0 |
| Perk regulates gene expression 1 26 1.620408163265306 0.4704807306772423 |
| Atf6 atf6 alpha activates chaperones 0 8 0.0 1.0 |
| Atf4 activates genes in response to endoplasmic reticulum stress 1 22 1.9298347910592808 0.4160065505344545 |
| Energy dependent regulation of mtor by lkb1 ampk 0 27 0.0 1.0 |
| Recruitment of numa to mitotic centrosomes 4 90 1.8958293292331347 0.1723284412806655 |
| Chemokine receptors bind chemokines 0 3 0.0 1.0 |
| Initiation of nuclear envelope ne reformation 0 20 0.0 1.0 |
| Defective chst14 causes eds musculocontractural type 0 4 0.0 1.0 |
| Defective b4galt7 causes eds progeroid type 0 13 0.0 1.0 |
| Sumoylation of transcription factors 0 18 0.0 1.0 |
| Glycogen storage diseases 0 10 0.0 1.0 |
| Processing and activation of sumo 0 10 0.0 1.0 |
| Rmts methylate histone arginines 0 36 0.0 1.0 |
| Hats acetylate histones 1 90 0.4522357257509745 0.8900614345422548 |
| Pkmts methylate histone lysines 2 46 1.8453800298062597 0.3051232152156647 |
| Hdacs deacetylate histones 0 40 0.0 1.0 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0 5 0.0 1.0 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 0 7 0.0 1.0 |
| Sumoylation of dna damage response and repair proteins 2 76 1.0939299955693398 0.5509866648628524 |
| Sumo is proteolytically processed 0 6 0.0 1.0 |
| Sumo is transferred from e1 to e2 ube2i ubc9 0 7 0.0 1.0 |
| Sumo is conjugated to e1 uba2 sae1 0 5 0.0 1.0 |
| Scavenging by class f receptors 0 5 0.0 1.0 |
| Scavenging by class a receptors 0 10 0.0 1.0 |
| Ecm proteoglycans 2 37 2.322014051522248 0.224257489169728 |
| Non integrin membrane ecm interactions 1 37 1.1240362811791382 0.5955662992954859 |
| Syndecan interactions 0 20 0.0 1.0 |
| Laminin interactions 1 23 1.8419294990723565 0.4301270919610729 |
| Sumoylation of ubiquitinylation proteins 1 39 1.0646616541353384 0.6149168035506691 |
| Defective chst3 causes sedcjd 0 4 0.0 1.0 |
| Wnt ligand biogenesis and trafficking 0 9 0.0 1.0 |
| Irf3 mediated induction of type i ifn 1 8 5.797667638483965 0.1775366954381628 |
| Diseases associated with glycosaminoglycan metabolism 1 26 1.620408163265306 0.4704807306772423 |
| Grb2 sos provides linkage to mapk signaling for integrins 0 9 0.0 1.0 |
| Integrin signaling 0 18 0.0 1.0 |
| Apoptotic cleavage of cell adhesion proteins 0 9 0.0 1.0 |
| Notch hlh transcription pathway 1 21 2.026530612244898 0.4015375820029667 |
| Hsf1 dependent transactivation 1 30 1.3963406052076002 0.5198923492291299 |
| Attenuation phase 0 22 0.0 1.0 |
| Cellular response to heat stress 2 93 0.8880381913168799 0.6609400372361673 |
| Hsf1 activation 0 25 0.0 1.0 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0 47 0.0 1.0 |
| Regulation of hsf1 mediated heat shock response 1 76 0.5374149659863946 0.8448074381544391 |
| Regulation by c flip 0 10 0.0 1.0 |
| Defects in biotin btn metabolism 0 8 0.0 1.0 |
| Glycogen synthesis 0 11 0.0 1.0 |
| Signaling by tgf beta receptor complex in cancer 0 8 0.0 1.0 |
| Loss of function of smad2 3 in cancer 0 7 0.0 1.0 |
| Nuclear pore complex npc disassembly 1 36 1.156268221574344 0.5855309260576435 |
| Detoxification of reactive oxygen species 1 24 1.7616681455190772 0.4439075633632242 |
| Trp channels 0 7 0.0 1.0 |
| Chromatin modifying enzymes 5 210 0.9862362109098268 0.5752902019482493 |
| Activation of kainate receptors upon glutamate binding 0 16 0.0 1.0 |
|
|
