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b8dc22f verified
term overlap setsize score pval
Interleukin 6 signaling 0 8 0.0 1.0
Formation of the cornified envelope 0 24 0.0 1.0
Copi mediated anterograde transport 0 89 0.0 1.0
Rna polymerase ii transcribes snrna genes 0 73 0.0 1.0
Pten regulation 0 128 0.0 1.0
Negative regulation of met activity 0 20 0.0 1.0
Met receptor activation 0 4 0.0 1.0
Signaling by met 0 64 0.0 1.0
Metabolism of fat soluble vitamins 0 29 0.0 1.0
Regulation of tp53 expression and degradation 0 33 0.0 1.0
Copi dependent golgi to er retrograde traffic 0 83 0.0 1.0
Keratinization 0 24 0.0 1.0
Regulation of tp53 activity through association with co factors 0 12 0.0 1.0
Regulation of tp53 activity through acetylation 0 30 0.0 1.0
Regulation of tp53 activity through phosphorylation 0 82 0.0 1.0
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0 13 0.0 1.0
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0 16 0.0 1.0
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0 18 0.0 1.0
Fgfr2 alternative splicing 0 26 0.0 1.0
Tp53 regulates transcription of death receptors and ligands 0 10 0.0 1.0
Tp53 regulates transcription of caspase activators and caspases 0 8 0.0 1.0
Regulation of tp53 activity through methylation 0 16 0.0 1.0
Copi independent golgi to er retrograde traffic 0 45 0.0 1.0
Intra golgi traffic 0 42 0.0 1.0
Retrograde transport at the trans golgi network 0 49 0.0 1.0
Dna strand elongation 0 35 0.0 1.0
Lagging strand synthesis 0 23 0.0 1.0
Processive synthesis on the lagging strand 0 17 0.0 1.0
Polymerase switching 0 16 0.0 1.0
Switching of origins to a post replicative state 0 85 0.0 1.0
Dna replication pre initiation 0 92 0.0 1.0
Activation of the pre replicative complex 0 33 0.0 1.0
Dna replication initiation 0 8 0.0 1.0
Orc1 removal from chromatin 0 65 0.0 1.0
G2 phase 0 4 0.0 1.0
M phase 0 355 0.0 1.0
Mitotic telophase cytokinesis 0 13 0.0 1.0
Mitotic prometaphase 0 198 0.0 1.0
Mitotic prophase 0 93 0.0 1.0
Cdt1 association with the cdc6 orc origin complex 0 54 0.0 1.0
Cdc6 association with the orc origin complex 0 12 0.0 1.0
Assembly of the orc complex at the origin of replication 0 20 0.0 1.0
Glycerophospholipid catabolism 0 4 0.0 1.0
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0 27 0.0 1.0
Pi5p regulates tp53 acetylation 0 9 0.0 1.0
Intra golgi and retrograde golgi to er traffic 0 181 0.0 1.0
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0 11 0.0 1.0
G1 s specific transcription 0 29 0.0 1.0
Tp53 regulates transcription of genes involved in cytochrome c release 0 16 0.0 1.0
Oncogenic mapk signaling 0 66 0.0 1.0
Transcription coupled nucleotide excision repair tc ner 0 82 0.0 1.0
Formation of tc ner pre incision complex 0 53 0.0 1.0
Highly calcium permeable nicotinic acetylcholine receptors 0 2 0.0 1.0
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors 0 1 0.0 1.0
Presynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0
Inflammasomes 0 12 0.0 1.0
Respiratory electron transport 0 101 0.0 1.0
Deposition of new cenpa containing nucleosomes at the centromere 0 34 0.0 1.0
Dual incision in tc ner 0 67 0.0 1.0
Post translational protein modification 0 1003 0.0 1.0
Global genome nucleotide excision repair gg ner 0 87 0.0 1.0
Nucleotide excision repair 0 114 0.0 1.0
Gap filling dna repair synthesis and ligation in gg ner 0 28 0.0 1.0
Formation of incision complex in gg ner 0 42 0.0 1.0
Dna damage recognition in gg ner 0 37 0.0 1.0
Cargo concentration in the er 0 23 0.0 1.0
Processing of dna double strand break ends 0 66 0.0 1.0
Dna double strand break response 0 49 0.0 1.0
Homologous dna pairing and strand exchange 0 41 0.0 1.0
Dual incision in gg ner 0 42 0.0 1.0
Trna modification in the nucleus and cytosol 0 43 0.0 1.0
Synthesis of wybutosine at g37 of trna phe 0 6 0.0 1.0
Fanconi anemia pathway 0 36 0.0 1.0
Ras signaling downstream of nf1 loss of function variants 0 5 0.0 1.0
Signaling by braf and raf1 fusions 0 53 0.0 1.0
Signaling by moderate kinase activity braf mutants 0 36 0.0 1.0
Complex i biogenesis 0 56 0.0 1.0
Neutrophil degranulation 1 319 3.102830188679245 0.2951904484295041
Choline catabolism 0 4 0.0 1.0
Tp53 regulates transcription of dna repair genes 0 61 0.0 1.0
Protein protein interactions at synapses 0 46 0.0 1.0
Neurexins and neuroligins 0 28 0.0 1.0
Rrna modification in the mitochondrion 0 6 0.0 1.0
Tp53 regulates transcription of cell cycle genes 0 43 0.0 1.0
Rrna modification in the nucleus and cytosol 0 63 0.0 1.0
Il 6 type cytokine receptor ligand interactions 0 6 0.0 1.0
Gdp fucose biosynthesis 0 6 0.0 1.0
Trna modification in the mitochondrion 0 9 0.0 1.0
Interleukin 4 and interleukin 13 signaling 0 40 0.0 1.0
Erbb2 regulates cell motility 0 6 0.0 1.0
Trna processing in the mitochondrion 0 5 0.0 1.0
Trna processing in the nucleus 0 60 0.0 1.0
Interleukin 10 signaling 0 6 0.0 1.0
Interleukin 6 family signaling 0 10 0.0 1.0
Antimicrobial peptides 0 7 0.0 1.0
Nonhomologous end joining nhej 0 41 0.0 1.0
Cyclin d associated events in g1 0 45 0.0 1.0
S phase 0 158 0.0 1.0
Signal attenuation 0 9 0.0 1.0
Irs activation 0 4 0.0 1.0
Purine catabolism 0 14 0.0 1.0
Purine salvage 0 12 0.0 1.0
Ketone body metabolism 0 7 0.0 1.0
Rna polymerase iii transcription 0 44 0.0 1.0
Rna polymerase iii transcription termination 0 24 0.0 1.0
Dna damage reversal 0 8 0.0 1.0
Resolution of abasic sites ap sites 0 41 0.0 1.0
Insulin receptor signalling cascade 0 31 0.0 1.0
Base excision repair ap site formation 0 23 0.0 1.0
Dna damage bypass 0 49 0.0 1.0
Death receptor signalling 0 120 0.0 1.0
Chromosome maintenance 0 100 0.0 1.0
Base excision repair 0 55 0.0 1.0
Rna polymerase i transcription 0 63 0.0 1.0
Rna polymerase i transcription termination 0 32 0.0 1.0
Rna polymerase ii transcription 1 969 0.9521694214876032 0.6668104066980932
Rna polymerase ii transcription termination 0 66 0.0 1.0
Purine ribonucleoside monophosphate biosynthesis 0 11 0.0 1.0
Dna repair 0 291 0.0 1.0
Signaling by insulin receptor 0 45 0.0 1.0
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0 14 0.0 1.0
Processing of capped intronless pre mrna 0 29 0.0 1.0
Beta oxidation of decanoyl coa to octanoyl coa coa 0 6 0.0 1.0
Beta oxidation of lauroyl coa to decanoyl coa coa 0 4 0.0 1.0
Mitochondrial fatty acid beta oxidation 0 33 0.0 1.0
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0 5 0.0 1.0
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0 9 0.0 1.0
Synthesis of ketone bodies 0 6 0.0 1.0
Rna polymerase iii transcription initiation from type 3 promoter 0 30 0.0 1.0
Rna polymerase iii transcription initiation from type 1 promoter 0 31 0.0 1.0
Platelet aggregation plug formation 0 20 0.0 1.0
Response to elevated platelet cytosolic ca2 0 71 0.0 1.0
Platelet activation signaling and aggregation 0 152 0.0 1.0
Tnf signaling 0 39 0.0 1.0
Platelet adhesion to exposed collagen 0 7 0.0 1.0
Synthesis of very long chain fatty acyl coas 0 17 0.0 1.0
Dissolution of fibrin clot 0 7 0.0 1.0
Trail signaling 0 6 0.0 1.0
Fasl cd95l signaling 0 5 0.0 1.0
Apoptotic execution phase 0 47 0.0 1.0
Triglyceride biosynthesis 1 7 169.65 0.0075297912401724
Fatty acyl coa biosynthesis 0 29 0.0 1.0
Mrna editing 0 4 0.0 1.0
Rna polymerase iii chain elongation 0 19 0.0 1.0
Synthesis of dna 0 117 0.0 1.0
Rna polymerase i promoter escape 0 42 0.0 1.0
Pyrimidine catabolism 0 6 0.0 1.0
Branched chain amino acid catabolism 0 22 0.0 1.0
Urea cycle 0 6 0.0 1.0
Galactose catabolism 0 5 0.0 1.0
Fructose catabolism 0 3 0.0 1.0
Glucose metabolism 0 80 0.0 1.0
Pyruvate metabolism 0 26 0.0 1.0
Gluconeogenesis 0 25 0.0 1.0
Glycogen breakdown glycogenolysis 0 13 0.0 1.0
Glycolysis 0 66 0.0 1.0
Histidine catabolism 0 3 0.0 1.0
Cyclin a cdk2 associated events at s phase entry 0 79 0.0 1.0
Mitotic spindle checkpoint 0 111 0.0 1.0
G1 s dna damage checkpoints 0 61 0.0 1.0
Stabilization of p53 0 51 0.0 1.0
G2 m checkpoints 0 134 0.0 1.0
G2 m dna replication checkpoint 0 5 0.0 1.0
G2 m dna damage checkpoint 0 66 0.0 1.0
Dna replication 0 137 0.0 1.0
Cell cycle mitotic 0 498 0.0 1.0
Cyclin a b1 b2 associated events during g2 m transition 0 24 0.0 1.0
Cell cycle checkpoints 0 257 0.0 1.0
Propionyl coa catabolism 0 5 0.0 1.0
Lysine catabolism 0 11 0.0 1.0
Tryptophan catabolism 0 6 0.0 1.0
Pyrimidine salvage 0 9 0.0 1.0
Transport of nucleotide sugars 0 4 0.0 1.0
Translation 0 289 0.0 1.0
Recycling of eif2 gdp 0 8 0.0 1.0
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0 59 0.0 1.0
Eukaryotic translation initiation 0 116 0.0 1.0
Rrna processing 0 202 0.0 1.0
Trna processing 0 109 0.0 1.0
Processing of capped intron containing pre mrna 0 239 0.0 1.0
Transport of mature transcript to cytoplasm 0 81 0.0 1.0
Mrna editing c to u conversion 0 2 0.0 1.0
Mrna splicing 0 188 0.0 1.0
Mrna splicing minor pathway 0 52 0.0 1.0
Mrna capping 0 29 0.0 1.0
Pyruvate metabolism and citric acid tca cycle 0 48 0.0 1.0
Citric acid cycle tca cycle 0 21 0.0 1.0
Metabolism of carbohydrates 0 201 0.0 1.0
Ethanol oxidation 1 5 254.525 0.0053836994107949
Pentose phosphate pathway 0 13 0.0 1.0
Metabolism of amino acids and derivatives 0 281 0.0 1.0
Creatine metabolism 0 6 0.0 1.0
Rna polymerase i transcription initiation 0 49 0.0 1.0
Beta oxidation of octanoyl coa to hexanoyl coa 0 5 0.0 1.0
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0 26 0.0 1.0
Homology directed repair 0 106 0.0 1.0
Cardiac conduction 0 43 0.0 1.0
Phase 3 rapid repolarisation 0 1 0.0 1.0
Phase 4 resting membrane potential 0 2 0.0 1.0
Metabolism of lipids 1 508 1.9088757396449705 0.4301974242082971
Organic cation anion zwitterion transport 0 3 0.0 1.0
Organic cation transport 0 3 0.0 1.0
Aflatoxin activation and detoxification 0 6 0.0 1.0
Diseases of mismatch repair mmr 0 5 0.0 1.0
Negative regulation of tcf dependent signaling by dvl interacting proteins 0 5 0.0 1.0
Phase 0 rapid depolarisation 0 6 0.0 1.0
Mitochondrial translation 0 93 0.0 1.0
Release of hh np from the secreting cell 0 2 0.0 1.0
Signaling by retinoic acid 1 26 40.64 0.0277087127163546
Mismatch repair 0 17 0.0 1.0
Synthesis of diphthamide eef2 0 8 0.0 1.0
Signaling by hedgehog 0 122 0.0 1.0
Hedgehog ligand biogenesis 0 53 0.0 1.0
Tnfr1 induced nfkappab signaling pathway 0 28 0.0 1.0
Regulation of tnfr1 signaling 0 31 0.0 1.0
Programmed cell death 0 179 0.0 1.0
Ra biosynthesis pathway 1 9 127.2125 0.0096716725706127
Phase 2 plateau phase 0 3 0.0 1.0
Transcriptional regulation by small rnas 0 57 0.0 1.0
Physiological factors 0 6 0.0 1.0
Intraflagellar transport 0 48 0.0 1.0
Bbsome mediated cargo targeting to cilium 0 18 0.0 1.0
Cargo trafficking to the periciliary membrane 0 43 0.0 1.0
Vxpx cargo targeting to cilium 0 18 0.0 1.0
Anchoring of the basal body to the plasma membrane 0 95 0.0 1.0
Disorders of transmembrane transporters 0 115 0.0 1.0
Slc transporter disorders 0 54 0.0 1.0
Abc transporter disorders 0 61 0.0 1.0
Cilium assembly 0 183 0.0 1.0
Activation of anterior hox genes in hindbrain development during early embryogenesis 0 60 0.0 1.0
Hedgehog off state 0 96 0.0 1.0
Degradation of gli1 by the proteasome 0 53 0.0 1.0
Diseases associated with glycosylation precursor biosynthesis 0 16 0.0 1.0
Clec7a dectin 1 signaling 0 85 0.0 1.0
Clec7a dectin 1 induces nfat activation 0 10 0.0 1.0
Dectin 1 mediated noncanonical nf kb signaling 0 53 0.0 1.0
Irak4 deficiency tlr2 4 0 4 0.0 1.0
Ikba variant leads to eda id 0 7 0.0 1.0
Piwi interacting rna pirna biogenesis 0 16 0.0 1.0
Metabolic disorders of biological oxidation enzymes 0 13 0.0 1.0
Ion homeostasis 0 31 0.0 1.0
Tnfr1 induced proapoptotic signaling 0 13 0.0 1.0
Pyroptosis 0 16 0.0 1.0
Caspase activation via extrinsic apoptotic signalling pathway 0 18 0.0 1.0
Signaling by lrp5 mutants 0 2 0.0 1.0
Defective galnt3 causes hftc 0 1 0.0 1.0
Gpcr ligand binding 0 46 0.0 1.0
Presynaptic function of kainate receptors 0 13 0.0 1.0
Interconversion of nucleotide di and triphosphates 0 26 0.0 1.0
Signaling by ctnnb1 phospho site mutants 0 15 0.0 1.0
Signaling by wnt in cancer 0 25 0.0 1.0
Sumoylation of immune response proteins 0 10 0.0 1.0
Sumoylation of dna methylation proteins 0 16 0.0 1.0
Repression of wnt target genes 0 13 0.0 1.0
Defective lfng causes scdo3 0 3 0.0 1.0
Regulation of fzd by ubiquitination 0 9 0.0 1.0
Degradation of dvl 0 50 0.0 1.0
Degradation of axin 0 48 0.0 1.0
Sumoylation of dna replication proteins 0 46 0.0 1.0
Asymmetric localization of pcp proteins 0 54 0.0 1.0
Sumoylation of rna binding proteins 0 47 0.0 1.0
Thrombin signalling through proteinase activated receptors pars 0 21 0.0 1.0
Sumoylation of chromatin organization proteins 0 58 0.0 1.0
Mitotic g1 phase and g1 s transition 0 143 0.0 1.0
Mitotic g2 g2 m phases 0 186 0.0 1.0
Disassembly of the destruction complex and recruitment of axin to the membrane 0 24 0.0 1.0
Defective c1galt1c1 causes tnps 0 2 0.0 1.0
Wnt5a dependent internalization of fzd4 0 13 0.0 1.0
Interleukin 3 interleukin 5 and gm csf signaling 0 31 0.0 1.0
Uptake and actions of bacterial toxins 0 23 0.0 1.0
Uptake and function of diphtheria toxin 0 5 0.0 1.0
Dna methylation 0 14 0.0 1.0
N glycan trimming in the er and calnexin calreticulin cycle 0 32 0.0 1.0
Diseases of immune system 0 15 0.0 1.0
Myogenesis 0 22 0.0 1.0
Toxicity of botulinum toxin type d botd 0 3 0.0 1.0
Negative epigenetic regulation of rrna expression 0 61 0.0 1.0
B wich complex positively regulates rrna expression 0 45 0.0 1.0
Positive epigenetic regulation of rrna expression 0 60 0.0 1.0
Miscellaneous transport and binding events 0 17 0.0 1.0
Vegfr2 mediated cell proliferation 0 15 0.0 1.0
Vegfr2 mediated vascular permeability 0 22 0.0 1.0
Regulated necrosis 0 42 0.0 1.0
Ripk1 mediated regulated necrosis 0 26 0.0 1.0
Uptake and function of anthrax toxins 0 10 0.0 1.0
Pink1 prkn mediated mitophagy 0 17 0.0 1.0
Mitophagy 0 24 0.0 1.0
O glycosylation of tsr domain containing proteins 0 5 0.0 1.0
O linked glycosylation 0 35 0.0 1.0
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0 12 0.0 1.0
Signaling by rnf43 mutants 0 4 0.0 1.0
Sensing of dna double strand breaks 0 6 0.0 1.0
Dectin 2 family 0 4 0.0 1.0
Cd209 dc sign signaling 0 18 0.0 1.0
Map2k and mapk activation 0 31 0.0 1.0
Raf activation 0 33 0.0 1.0
Tnfs bind their physiological receptors 0 1 0.0 1.0
Diseases of metabolism 0 131 0.0 1.0
Rho gtpases activate nadph oxidases 0 13 0.0 1.0
Tnfr2 non canonical nf kb pathway 0 58 0.0 1.0
Rho gtpases activate rhotekin and rhophilins 0 8 0.0 1.0
Rho gtpases activate formins 0 133 0.0 1.0
Rho gtpases activate wasps and waves 0 33 0.0 1.0
Constitutive signaling by akt1 e17k in cancer 0 25 0.0 1.0
Infectious disease 1 619 1.5480582524271844 0.4980681655674492
Diseases of carbohydrate metabolism 0 23 0.0 1.0
Formation of xylulose 5 phosphate 0 5 0.0 1.0
Metallothioneins bind metals 0 2 0.0 1.0
Clec7a inflammasome pathway 0 4 0.0 1.0
Response to metal ions 0 5 0.0 1.0
Fgfrl1 modulation of fgfr1 signaling 0 2 0.0 1.0
Regulation of ras by gaps 0 57 0.0 1.0
Termination of translesion dna synthesis 0 34 0.0 1.0
Translesion synthesis by polk 0 17 0.0 1.0
Diseases of signal transduction by growth factor receptors and second messengers 0 333 0.0 1.0
Negative feedback regulation of mapk pathway 0 6 0.0 1.0
Negative regulation of mapk pathway 0 36 0.0 1.0
Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 0 5 0.0 1.0
Resolution of d loop structures 0 32 0.0 1.0
Dna double strand break repair 0 137 0.0 1.0
Cd22 mediated bcr regulation 0 2 0.0 1.0
Metalloprotease dubs 0 20 0.0 1.0
Ovarian tumor domain proteases 0 34 0.0 1.0
Ub specific processing proteases 0 151 0.0 1.0
Josephin domain dubs 0 9 0.0 1.0
Uch proteinases 0 79 0.0 1.0
Deubiquitination 0 221 0.0 1.0
Diseases associated with surfactant metabolism 0 1 0.0 1.0
Mapk6 mapk4 signaling 0 77 0.0 1.0
Regulation of tlr by endogenous ligand 0 3 0.0 1.0
Hdr through homologous recombination hrr 0 66 0.0 1.0
Hdr through mmej alt nhej 0 11 0.0 1.0
Hdr through single strand annealing ssa 0 35 0.0 1.0
Map3k8 tpl2 dependent mapk1 3 activation 0 14 0.0 1.0
Surfactant metabolism 0 8 0.0 1.0
Mapk family signaling cascades 0 212 0.0 1.0
Lgi adam interactions 0 5 0.0 1.0
Defective cftr causes cystic fibrosis 0 54 0.0 1.0
Protein repair 0 5 0.0 1.0
Signaling by fgfr1 in disease 0 29 0.0 1.0
C type lectin receptors clrs 0 100 0.0 1.0
Signaling by fgfr4 in disease 0 11 0.0 1.0
Signaling by fgfr4 0 26 0.0 1.0
Fructose metabolism 0 5 0.0 1.0
Pcna dependent long patch base excision repair 0 24 0.0 1.0
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0 7 0.0 1.0
Constitutive signaling by egfrviii 0 14 0.0 1.0
Gli proteins bind promoters of hh responsive genes to promote transcription 0 2 0.0 1.0
Activation of smo 0 11 0.0 1.0
Tp53 regulates transcription of cell death genes 0 34 0.0 1.0
Regulation of tp53 activity 0 146 0.0 1.0
Hedgehog on state 0 70 0.0 1.0
Vesicle mediated transport 1 546 1.7688073394495414 0.4543179004302342
Ligand receptor interactions 0 2 0.0 1.0
Rho gtpases activate paks 0 19 0.0 1.0
Rho gtpases activate rocks 0 19 0.0 1.0
Tnfr1 mediated ceramide production 0 3 0.0 1.0
Rho gtpases activate iqgaps 0 26 0.0 1.0
Rho gtpases activate ktn1 0 11 0.0 1.0
Rho gtpases activate cit 0 18 0.0 1.0
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0 14 0.0 1.0
Rho gtpases activate pkns 0 40 0.0 1.0
Trafficking of myristoylated proteins to the cilium 0 4 0.0 1.0
Tp53 regulates metabolic genes 0 84 0.0 1.0
Phospholipase c mediated cascade fgfr2 0 3 0.0 1.0
Phospholipase c mediated cascade fgfr4 0 3 0.0 1.0
Downstream signaling of activated fgfr1 0 15 0.0 1.0
Signaling by fgfr3 0 27 0.0 1.0
Signaling by fgfr2 0 51 0.0 1.0
Signaling by fgfr1 0 28 0.0 1.0
Negative regulation of fgfr4 signaling 0 17 0.0 1.0
Negative regulation of fgfr3 signaling 0 17 0.0 1.0
Negative regulation of fgfr2 signaling 0 17 0.0 1.0
Negative regulation of fgfr1 signaling 0 17 0.0 1.0
Pi 3k cascade fgfr4 0 8 0.0 1.0
Shc mediated cascade fgfr4 0 8 0.0 1.0
Downstream signaling of activated fgfr4 0 14 0.0 1.0
Frs mediated fgfr4 signaling 0 9 0.0 1.0
Pi 3k cascade fgfr3 0 8 0.0 1.0
Downstream signaling of activated fgfr3 0 14 0.0 1.0
Frs mediated fgfr3 signaling 0 9 0.0 1.0
Shc mediated cascade fgfr3 0 8 0.0 1.0
Frs mediated fgfr2 signaling 0 9 0.0 1.0
Downstream signaling of activated fgfr2 0 14 0.0 1.0
Pi 3k cascade fgfr2 0 8 0.0 1.0
Frs mediated fgfr1 signaling 0 9 0.0 1.0
Pi 3k cascade fgfr1 0 8 0.0 1.0
Shc mediated cascade fgfr1 0 8 0.0 1.0
Signaling by fgfr2 in disease 0 28 0.0 1.0
Transcriptional regulation of pluripotent stem cells 0 16 0.0 1.0
Beta oxidation of hexanoyl coa to butanoyl coa 0 5 0.0 1.0
Insulin receptor recycling 0 15 0.0 1.0
Regulation of localization of foxo transcription factors 0 13 0.0 1.0
Foxo mediated transcription 0 47 0.0 1.0
Chaperone mediated autophagy 0 16 0.0 1.0
Lipophagy 0 8 0.0 1.0
Autophagy 0 130 0.0 1.0
Hcmv late events 0 62 0.0 1.0
Assembly and cell surface presentation of nmda receptors 0 28 0.0 1.0
Hcmv early events 0 79 0.0 1.0
Hcmv infection 0 102 0.0 1.0
Foxo mediated transcription of cell death genes 0 12 0.0 1.0
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 1 19 56.48333333333333 0.0203181815952763
Flt3 signaling 0 27 0.0 1.0
Diseases of base excision repair 0 4 0.0 1.0
Negative regulation of notch4 signaling 0 49 0.0 1.0
Class i peroxisomal membrane protein import 0 19 0.0 1.0
Activated ntrk3 signals through pi3k 0 4 0.0 1.0
Transport to the golgi and subsequent modification 0 148 0.0 1.0
Molybdenum cofactor biosynthesis 0 7 0.0 1.0
Traf6 mediated induction of tak1 complex within tlr4 complex 0 11 0.0 1.0
Irak2 mediated activation of tak1 complex 0 9 0.0 1.0
Protein localization 1 142 7.123404255319149 0.1430282918957972
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0 18 0.0 1.0
Late endosomal microautophagy 0 29 0.0 1.0
Postmitotic nuclear pore complex npc reformation 0 27 0.0 1.0
Response of mtb to phagocytosis 0 20 0.0 1.0
Suppression of phagosomal maturation 0 11 0.0 1.0
Modulation by mtb of host immune system 0 4 0.0 1.0
Prevention of phagosomal lysosomal fusion 0 8 0.0 1.0
Infection with mycobacterium tuberculosis 0 21 0.0 1.0
Suppression of apoptosis 0 6 0.0 1.0
Estrogen dependent nuclear events downstream of esr membrane signaling 0 15 0.0 1.0
Estrogen stimulated signaling through prkcz 0 6 0.0 1.0
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0 11 0.0 1.0
Constitutive signaling by overexpressed erbb2 0 11 0.0 1.0
Response of eif2ak4 gcn2 to amino acid deficiency 0 94 0.0 1.0
Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis 0 4 0.0 1.0
Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 0 6 0.0 1.0
Long term potentiation 0 11 0.0 1.0
Egr2 and sox10 mediated initiation of schwann cell myelination 0 20 0.0 1.0
Activation of ampk downstream of nmdars 0 21 0.0 1.0
Activation of rac1 downstream of nmdars 0 6 0.0 1.0
Foxo mediated transcription of cell cycle genes 0 13 0.0 1.0
Regulation of foxo transcriptional activity by acetylation 0 10 0.0 1.0
Negative regulation of nmda receptor mediated neuronal transmission 0 14 0.0 1.0
Transcriptional regulation of granulopoiesis 0 34 0.0 1.0
Ikk complex recruitment mediated by rip1 0 16 0.0 1.0
Amino acids regulate mtorc1 0 45 0.0 1.0
Irak1 recruits ikk complex 0 12 0.0 1.0
Ion transport by p type atpases 0 31 0.0 1.0
Ngf stimulated transcription 0 22 0.0 1.0
Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose 0 3 0.0 1.0
Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake 0 3 0.0 1.0
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0 26 0.0 1.0
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0 7 0.0 1.0
Activated ntrk2 signals through frs2 and frs3 0 7 0.0 1.0
Activated ntrk2 signals through pi3k 0 4 0.0 1.0
Erythropoietin activates ras 0 11 0.0 1.0
Erythropoietin activates stat5 0 4 0.0 1.0
Activated ntrk2 signals through fyn 0 4 0.0 1.0
Erythropoietin activates phospholipase c gamma plcg 0 5 0.0 1.0
Activated ntrk2 signals through ras 0 6 0.0 1.0
Nr1h2 and nr1h3 mediated signaling 0 31 0.0 1.0
Mecp2 regulates transcription factors 0 4 0.0 1.0
Mecp2 regulates transcription of neuronal ligands 0 4 0.0 1.0
Mecp2 regulates neuronal receptors and channels 0 12 0.0 1.0
Regulation of mecp2 expression and activity 0 30 0.0 1.0
Loss of mecp2 binding ability to the ncor smrt complex 0 7 0.0 1.0
Interleukin 21 signaling 0 5 0.0 1.0
Interleukin 27 signaling 0 8 0.0 1.0
Erythropoietin activates phosphoinositide 3 kinase pi3k 0 8 0.0 1.0
Ntrk2 activates rac1 0 3 0.0 1.0
Activated ntrk2 signals through cdk5 0 3 0.0 1.0
Peroxisomal protein import 0 51 0.0 1.0
Negative regulators of ddx58 ifih1 signaling 0 29 0.0 1.0
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0 13 0.0 1.0
Traf6 mediated nf kb activation 0 22 0.0 1.0
Traf6 mediated irf7 activation 0 15 0.0 1.0
Nonsense mediated decay nmd 0 110 0.0 1.0
Traf3 dependent irf activation pathway 0 13 0.0 1.0
Transferrin endocytosis and recycling 0 18 0.0 1.0
Iron uptake and transport 0 38 0.0 1.0
Endosomal sorting complex required for transport escrt 0 30 0.0 1.0
O linked glycosylation of mucins 0 22 0.0 1.0
Interferon signaling 0 128 0.0 1.0
Regulation of ifna signaling 0 8 0.0 1.0
Regulation of signaling by cbl 0 18 0.0 1.0
Interleukin receptor shc signaling 0 14 0.0 1.0
Meiotic recombination 0 31 0.0 1.0
Interferon alpha beta signaling 0 31 0.0 1.0
Rhof gtpase cycle 0 42 0.0 1.0
Activated ntrk3 signals through ras 0 6 0.0 1.0
Signaling by ntrk3 trkc 0 15 0.0 1.0
Blood group systems biosynthesis 0 5 0.0 1.0
Tysnd1 cleaves peroxisomal proteins 0 7 0.0 1.0
Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0 11 0.0 1.0
Interleukin 23 signaling 0 5 0.0 1.0
Stat5 activation 0 4 0.0 1.0
Diseases of programmed cell death 0 53 0.0 1.0
Heme signaling 0 36 0.0 1.0
Regulation of hmox1 expression and activity 0 58 0.0 1.0
Cytoprotection by hmox1 0 110 0.0 1.0
Rhobtb gtpase cycle 0 33 0.0 1.0
Flt3 signaling by cbl mutants 0 4 0.0 1.0
Flt3 signaling through src family kinases 0 2 0.0 1.0
Negative regulation of flt3 0 8 0.0 1.0
Rhobtb3 atpase cycle 0 9 0.0 1.0
Inactivation of csf3 g csf signaling 0 17 0.0 1.0
Regulation of bach1 activity 0 10 0.0 1.0
Signaling by flt3 itd and tkd mutants 0 12 0.0 1.0
Stat5 activation downstream of flt3 itd mutants 0 6 0.0 1.0
Stat3 nuclear events downstream of alk signaling 0 6 0.0 1.0
Alk mutants bind tkis 0 12 0.0 1.0
Signaling by alk in cancer 0 52 0.0 1.0
Rnd1 gtpase cycle 0 36 0.0 1.0
Rnd2 gtpase cycle 0 40 0.0 1.0
Rnd3 gtpase cycle 0 39 0.0 1.0
Translation of sars cov 2 structural proteins 0 41 0.0 1.0
Maturation of sars cov 2 nucleoprotein 0 13 0.0 1.0
Signaling by flt3 fusion proteins 0 16 0.0 1.0
Sensory perception 0 84 0.0 1.0
Cellular response to starvation 0 139 0.0 1.0
Cellular response to chemical stress 0 133 0.0 1.0
Antigen activates b cell receptor bcr leading to generation of second messengers 0 20 0.0 1.0
Factors involved in megakaryocyte development and platelet production 0 117 0.0 1.0
Kinesins 0 47 0.0 1.0
Antigen presentation folding assembly and peptide loading of class i mhc 0 24 0.0 1.0
Class i mhc mediated antigen processing presentation 0 295 0.0 1.0
Antigen processing ubiquitination proteasome degradation 0 250 0.0 1.0
Growth hormone receptor signaling 0 15 0.0 1.0
Gaba b receptor activation 0 16 0.0 1.0
Gaba receptor activation 0 18 0.0 1.0
Serine biosynthesis 0 7 0.0 1.0
Amyloid fiber formation 0 41 0.0 1.0
Termination of o glycan biosynthesis 0 4 0.0 1.0
Reactions specific to the complex n glycan synthesis pathway 0 6 0.0 1.0
N glycan antennae elongation 0 8 0.0 1.0
N glycan antennae elongation in the medial trans golgi 0 15 0.0 1.0
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0 10 0.0 1.0
Defective intrinsic pathway for apoptosis 0 24 0.0 1.0
Nuclear events stimulated by alk signaling in cancer 0 17 0.0 1.0
Sensory perception of taste 0 4 0.0 1.0
Signaling by rho gtpases miro gtpases and rhobtb3 0 593 0.0 1.0
Miro gtpase cycle 0 8 0.0 1.0
Attachment and entry 0 4 0.0 1.0
Alpha protein kinase 1 signaling pathway 0 9 0.0 1.0
Maturation of sars cov 2 spike protein 0 24 0.0 1.0
Defective ripk1 mediated regulated necrosis 0 6 0.0 1.0
Killing mechanisms 0 9 0.0 1.0
Parasite infection 0 50 0.0 1.0
Fcgr3a mediated il10 synthesis 0 23 0.0 1.0
Selective autophagy 0 67 0.0 1.0
Anti inflammatory response favouring leishmania parasite infection 0 46 0.0 1.0
Cd163 mediating an anti inflammatory response 0 5 0.0 1.0
Sensory processing of sound by outer hair cells of the cochlea 0 25 0.0 1.0
Defective factor viii causes hemophilia a 0 3 0.0 1.0
Purinergic signaling in leishmaniasis infection 0 12 0.0 1.0
Pexophagy 0 9 0.0 1.0
Adora2b mediated anti inflammatory cytokines production 0 30 0.0 1.0
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0 17 0.0 1.0
Sensory processing of sound 0 40 0.0 1.0
Leishmania infection 0 110 0.0 1.0
Signaling by mapk mutants 0 4 0.0 1.0
Defects of contact activation system cas and kallikrein kinin system kks 0 5 0.0 1.0
Response of eif2ak1 hri to heme deficiency 0 10 0.0 1.0
Ras processing 0 19 0.0 1.0
N glycan trimming and elongation in the cis golgi 0 4 0.0 1.0
Aggrephagy 0 34 0.0 1.0
Signaling by mras complex mutants 0 8 0.0 1.0
Signaling by erbb2 ecd mutants 0 15 0.0 1.0
Defective factor ix causes hemophilia b 0 3 0.0 1.0
Sealing of the nuclear envelope ne by escrt iii 0 26 0.0 1.0
Transcriptional regulation of testis differentiation 0 4 0.0 1.0
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0 20 0.0 1.0
Translation of sars cov 1 structural proteins 0 22 0.0 1.0
Maturation of sars cov 1 spike protein 0 5 0.0 1.0
Maturation of protein 3a 0 5 0.0 1.0
Maturation of sars cov 1 nucleoprotein 0 9 0.0 1.0
Flt3 signaling in disease 0 22 0.0 1.0
Sars cov infections 1 128 7.919685039370079 0.1298034117972014
Translation of replicase and assembly of the replication transcription complex 0 13 0.0 1.0
Potential therapeutics for sars 1 68 15.101492537313431 0.0709977095462976
Sars cov 1 infection 0 42 0.0 1.0
Diseases of dna repair 0 33 0.0 1.0
Diseases of mitotic cell cycle 0 38 0.0 1.0
Nervous system development 0 443 0.0 1.0
Signaling by csf3 g csf 0 22 0.0 1.0
Signaling by membrane tethered fusions of pdgfra or pdgfrb 0 3 0.0 1.0
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0 11 0.0 1.0
Defective f9 activation 0 1 0.0 1.0
Signaling by pdgfr in disease 0 17 0.0 1.0
Inhibition of dna recombination at telomere 0 28 0.0 1.0
Signaling by kit in disease 0 18 0.0 1.0
Sars cov 2 infection 0 62 0.0 1.0
Beta oxidation of butanoyl coa to acetyl coa 0 5 0.0 1.0
Interleukin 1 signaling 0 82 0.0 1.0
Interleukin 2 signaling 0 5 0.0 1.0
Runx1 regulates estrogen receptor mediated transcription 1 5 254.525 0.0053836994107949
Gaba synthesis release reuptake and degradation 0 12 0.0 1.0
Transcriptional regulation by runx1 1 149 6.7817567567567565 0.1495719758406173
Transcriptional regulation by runx2 0 100 0.0 1.0
Transcriptional regulation by runx3 0 86 0.0 1.0
Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 0 3 0.0 1.0
Protein methylation 0 16 0.0 1.0
Inla mediated entry of listeria monocytogenes into host cells 0 9 0.0 1.0
Listeria monocytogenes entry into host cells 0 21 0.0 1.0
Regulation of runx1 expression and activity 0 17 0.0 1.0
Rab gefs exchange gtp for gdp on rabs 0 79 0.0 1.0
Met receptor recycling 0 10 0.0 1.0
Met activates rap1 and rac1 0 11 0.0 1.0
Met interacts with tns proteins 0 4 0.0 1.0
Inlb mediated entry of listeria monocytogenes into host cell 0 15 0.0 1.0
Creb3 factors activate genes 0 3 0.0 1.0
Met activates ptk2 signaling 0 19 0.0 1.0
Rab geranylgeranylation 0 54 0.0 1.0
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0 5 0.0 1.0
Rrna processing in the mitochondrion 0 10 0.0 1.0
Met promotes cell motility 0 29 0.0 1.0
Receptor mediated mitophagy 0 10 0.0 1.0
Digestion 0 1 0.0 1.0
Runx1 regulates expression of components of tight junctions 0 4 0.0 1.0
Collagen chain trimerization 0 13 0.0 1.0
Regulation of pten gene transcription 0 56 0.0 1.0
Regulation of pten mrna translation 0 9 0.0 1.0
Regulation of runx3 expression and activity 0 52 0.0 1.0
Runx3 regulates notch signaling 0 11 0.0 1.0
Runx3 regulates cdkn1a transcription 0 7 0.0 1.0
Runx2 regulates genes involved in cell migration 0 5 0.0 1.0
Runx2 regulates bone development 0 26 0.0 1.0
Runx2 regulates chondrocyte maturation 0 3 0.0 1.0
Runx2 regulates osteoblast differentiation 0 20 0.0 1.0
Regulation of runx2 expression and activity 0 61 0.0 1.0
Runx1 regulates transcription of genes involved in wnt signaling 0 3 0.0 1.0
Runx1 regulates transcription of genes involved in interleukin signaling 0 4 0.0 1.0
Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0 5 0.0 1.0
Runx1 regulates transcription of genes involved in bcr signaling 0 4 0.0 1.0
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0 36 0.0 1.0
Runx1 regulates transcription of genes involved in differentiation of keratinocytes 0 4 0.0 1.0
Runx1 regulates transcription of genes involved in differentiation of hscs 0 68 0.0 1.0
Esr mediated signaling 1 136 7.444444444444445 0.1373830242880762
Aryl hydrocarbon receptor signalling 0 7 0.0 1.0
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0 39 0.0 1.0
Tfap2 ap 2 family regulates transcription of cell cycle factors 0 5 0.0 1.0
Competing endogenous rnas cernas regulate pten translation 0 8 0.0 1.0
Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0 7 0.0 1.0
Negative regulation of activity of tfap2 ap 2 family transcription factors 0 7 0.0 1.0
Phosphate bond hydrolysis by ntpdase proteins 0 4 0.0 1.0
Synaptic adhesion like molecules 0 11 0.0 1.0
Ptk6 expression 0 2 0.0 1.0
Ptk6 regulates rho gtpases ras gtpase and map kinases 0 13 0.0 1.0
Ptk6 regulates cell cycle 0 5 0.0 1.0
Ptk6 regulates rtks and their effectors akt1 and dok1 0 7 0.0 1.0
Ptk6 regulates proteins involved in rna processing 0 3 0.0 1.0
Wax and plasmalogen biosynthesis 0 5 0.0 1.0
Signaling by ptk6 0 36 0.0 1.0
Butyrophilin btn family interactions 0 5 0.0 1.0
Erbb2 activates ptk6 signaling 0 3 0.0 1.0
Transport of organic anions 0 3 0.0 1.0
Advanced glycosylation endproduct receptor signaling 0 9 0.0 1.0
Regulation of ifng signaling 0 10 0.0 1.0
Interferon gamma signaling 0 51 0.0 1.0
The nlrp3 inflammasome 0 10 0.0 1.0
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0 8 0.0 1.0
Transport of fatty acids 0 3 0.0 1.0
Processing of intronless pre mrnas 0 21 0.0 1.0
Slbp dependent processing of replication dependent histone pre mrnas 0 10 0.0 1.0
Gastrin creb signalling pathway via pkc and mapk 0 14 0.0 1.0
Signaling by fgfr2 iiia tm 0 18 0.0 1.0
Met activates ras signaling 0 11 0.0 1.0
Met activates pi3k akt signaling 0 6 0.0 1.0
E3 ubiquitin ligases ubiquitinate target proteins 0 40 0.0 1.0
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0 26 0.0 1.0
Vldlr internalisation and degradation 0 9 0.0 1.0
Vldl assembly 0 3 0.0 1.0
Reelin signalling pathway 0 3 0.0 1.0
Met activates ptpn11 0 5 0.0 1.0
Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0 27 0.0 1.0
Downregulation of erbb2 signaling 0 18 0.0 1.0
Ptk6 promotes hif1a stabilization 0 2 0.0 1.0
Clathrin mediated endocytosis 0 119 0.0 1.0
Cargo recognition for clathrin mediated endocytosis 0 78 0.0 1.0
Golgi to er retrograde transport 0 115 0.0 1.0
Interleukin 20 family signaling 0 11 0.0 1.0
Aurka activation by tpx2 0 73 0.0 1.0
Tbc rabgaps 0 39 0.0 1.0
Transcriptional regulation by ventx 0 37 0.0 1.0
Ret signaling 0 26 0.0 1.0
Signaling by fgfr3 fusions in cancer 0 10 0.0 1.0
Signaling by mst1 0 3 0.0 1.0
The role of gtse1 in g2 m progression after g2 checkpoint 0 67 0.0 1.0
Protein ubiquitination 0 58 0.0 1.0
Activation of the tfap2 ap 2 family of transcription factors 0 8 0.0 1.0
Interleukin 12 signaling 0 38 0.0 1.0
Regulation of pten localization 0 8 0.0 1.0
Mitochondrial calcium ion transport 0 21 0.0 1.0
Rac2 gtpase cycle 0 81 0.0 1.0
Rac1 gtpase cycle 0 152 0.0 1.0
Cdc42 gtpase cycle 0 134 0.0 1.0
Rhoc gtpase cycle 0 75 0.0 1.0
Rhob gtpase cycle 0 69 0.0 1.0
Rho gtpase cycle 0 387 0.0 1.0
Signaling by notch3 0 35 0.0 1.0
Robo receptors bind akap5 0 8 0.0 1.0
Regulation of expression of slits and robos 0 155 0.0 1.0
Rhod gtpase cycle 0 50 0.0 1.0
Calnexin calreticulin cycle 0 23 0.0 1.0
Extra nuclear estrogen signaling 0 47 0.0 1.0
Interleukin 37 signaling 0 12 0.0 1.0
Rab regulation of trafficking 0 107 0.0 1.0
Signaling by tgfb family members 0 79 0.0 1.0
Signaling by receptor tyrosine kinases 0 344 0.0 1.0
Signaling by nuclear receptors 2 178 12.637626262626265 0.0150294310764824
Intracellular signaling by second messengers 0 233 0.0 1.0
Signaling by erythropoietin 0 19 0.0 1.0
Signaling by ntrk2 trkb 0 18 0.0 1.0
Er quality control compartment erqc 0 18 0.0 1.0
Rhoq gtpase cycle 0 59 0.0 1.0
Rhoh gtpase cycle 0 32 0.0 1.0
Rhog gtpase cycle 0 71 0.0 1.0
Biosynthesis of maresins 0 1 0.0 1.0
Biosynthesis of epa derived spms 0 3 0.0 1.0
Biosynthesis of specialized proresolving mediators spms 0 6 0.0 1.0
Estrogen dependent gene expression 1 90 11.3438202247191 0.09296663956795
Noncanonical activation of notch3 0 8 0.0 1.0
Interleukin 36 pathway 0 1 0.0 1.0
Ticam1 traf6 dependent induction of tak1 complex 0 10 0.0 1.0
Ticam1 dependent activation of irf3 irf7 0 10 0.0 1.0
Tlr3 mediated ticam1 dependent programmed cell death 0 5 0.0 1.0
Notch4 activation and transmission of signal to the nucleus 0 8 0.0 1.0
Notch4 intracellular domain regulates transcription 0 15 0.0 1.0
Signaling by notch4 0 71 0.0 1.0
Notch3 intracellular domain regulates transcription 0 18 0.0 1.0
Notch3 activation and transmission of signal to the nucleus 0 18 0.0 1.0
Rhot1 gtpase cycle 0 5 0.0 1.0
Rhov gtpase cycle 0 35 0.0 1.0
Rac3 gtpase cycle 0 83 0.0 1.0
Rhobtb1 gtpase cycle 0 22 0.0 1.0
Rhou gtpase cycle 0 39 0.0 1.0
Rhobtb2 gtpase cycle 0 22 0.0 1.0
Rhoj gtpase cycle 0 55 0.0 1.0
Loss of function of mecp2 in rett syndrome 0 12 0.0 1.0
Regulation of pten stability and activity 0 63 0.0 1.0
Transcriptional regulation by mecp2 0 45 0.0 1.0
Interleukin 35 signalling 0 9 0.0 1.0
Aspartate and asparagine metabolism 0 7 0.0 1.0
Phenylalanine and tyrosine metabolism 0 6 0.0 1.0
Tyrosine catabolism 0 2 0.0 1.0
Metabolism of steroids 1 103 9.885294117647058 0.1057252119813504
Nucleotide salvage 0 20 0.0 1.0
Nucleotide biosynthesis 0 16 0.0 1.0
Nucleotide catabolism 0 22 0.0 1.0
Carboxyterminal post translational modifications of tubulin 0 25 0.0 1.0
Cellular responses to stimuli 0 614 0.0 1.0
Digestion and absorption 0 1 0.0 1.0
Metabolism of rna 0 647 0.0 1.0
Runx3 regulates bcl2l11 bim transcription 0 5 0.0 1.0
Runx3 regulates p14 arf 0 11 0.0 1.0
Runx3 regulates yap1 mediated transcription 0 6 0.0 1.0
Neddylation 0 185 0.0 1.0
Runx3 regulates wnt signaling 0 8 0.0 1.0
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0 33 0.0 1.0
Processing of smdt1 0 16 0.0 1.0
Cristae formation 0 27 0.0 1.0
Runx3 regulates immune response and cell migration 0 4 0.0 1.0
Transcriptional regulation by e2f6 0 34 0.0 1.0
Chylomicron assembly 0 5 0.0 1.0
Assembly of active lpl and lipc lipase complexes 0 7 0.0 1.0
Hdl assembly 0 6 0.0 1.0
Oas antiviral response 0 6 0.0 1.0
Interleukin 15 signaling 0 8 0.0 1.0
Glycogen metabolism 0 20 0.0 1.0
Rhoa gtpase cycle 0 134 0.0 1.0
Triglyceride metabolism 1 20 53.50526315789474 0.0213770889355645
Metabolism of cofactors 0 15 0.0 1.0
Fatty acid metabolism 0 117 0.0 1.0
G beta gamma signalling through cdc42 0 14 0.0 1.0
Lipid particle organization 0 1 0.0 1.0
Glutamate and glutamine metabolism 0 14 0.0 1.0
Phenylalanine metabolism 0 4 0.0 1.0
Hdl remodeling 0 3 0.0 1.0
Vldl clearance 0 4 0.0 1.0
Plasma lipoprotein clearance 1 23 46.19545454545455 0.0245475710798989
Ldl remodeling 0 2 0.0 1.0
Ldl clearance 0 17 0.0 1.0
Chylomicron clearance 0 4 0.0 1.0
Hdl clearance 1 2 1018.4 0.0021566506862345
Chylomicron remodeling 0 4 0.0 1.0
Plasma lipoprotein remodeling 0 12 0.0 1.0
Plasma lipoprotein assembly 0 12 0.0 1.0
Interleukin 9 signaling 0 4 0.0 1.0
Interleukin 2 family signaling 0 21 0.0 1.0
Activation of kainate receptors upon glutamate binding 0 16 0.0 1.0
Ionotropic activity of kainate receptors 0 3 0.0 1.0
Chondroitin sulfate dermatan sulfate metabolism 0 32 0.0 1.0
Signaling by egfr 0 40 0.0 1.0
Retrograde neurotrophin signalling 0 12 0.0 1.0
Interactions of rev with host cellular proteins 0 37 0.0 1.0
Unwinding of dna 0 12 0.0 1.0
Phosphorylation of emi1 0 6 0.0 1.0
Phosphorylation of the apc c 0 20 0.0 1.0
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0 20 0.0 1.0
Activation of atr in response to replication stress 0 38 0.0 1.0
Apc cdc20 mediated degradation of nek2a 0 25 0.0 1.0
Interactions of vpr with host cellular proteins 0 37 0.0 1.0
Plasma lipoprotein assembly remodeling and clearance 1 40 26.015384615384612 0.0423379310763625
Activation of c3 and c5 0 1 0.0 1.0
Telomere c strand synthesis initiation 0 13 0.0 1.0
Telomere c strand lagging strand synthesis 0 37 0.0 1.0
Processive synthesis on the c strand of the telomere 0 21 0.0 1.0
Polymerase switching on the c strand of the telomere 0 28 0.0 1.0
Glutathione synthesis and recycling 0 8 0.0 1.0
Transport and synthesis of paps 0 4 0.0 1.0
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0 68 0.0 1.0
Assembly of the hiv virion 0 15 0.0 1.0
Srp dependent cotranslational protein targeting to membrane 0 108 0.0 1.0
Darpp 32 events 0 20 0.0 1.0
Gab1 signalosome 0 10 0.0 1.0
Downstream signal transduction 0 23 0.0 1.0
Regulation of beta cell development 0 22 0.0 1.0
Synthesis of ip3 and ip4 in the cytosol 0 20 0.0 1.0
Synthesis of ip2 ip and ins in the cytosol 0 12 0.0 1.0
Synthesis of pyrophosphates in the cytosol 0 10 0.0 1.0
Organelle biogenesis and maintenance 0 268 0.0 1.0
Fgfr2 mutant receptor activation 0 18 0.0 1.0
Fgfr1 mutant receptor activation 0 22 0.0 1.0
Signaling by cytosolic fgfr1 fusion mutants 0 18 0.0 1.0
Cytosolic sensors of pathogen associated dna 0 56 0.0 1.0
Sting mediated induction of host immune responses 0 10 0.0 1.0
Egfr downregulation 0 22 0.0 1.0
Nef mediated cd8 down regulation 0 6 0.0 1.0
Acetylcholine binding and downstream events 0 2 0.0 1.0
Norepinephrine neurotransmitter release cycle 0 12 0.0 1.0
Serotonin neurotransmitter release cycle 0 14 0.0 1.0
Rip mediated nfkb activation via zbp1 0 16 0.0 1.0
Extension of telomeres 0 52 0.0 1.0
Nuclear import of rev protein 0 34 0.0 1.0
Apobec3g mediated resistance to hiv 1 infection 0 4 0.0 1.0
Shc1 events in egfr signaling 0 7 0.0 1.0
Apc c mediated degradation of cell cycle proteins 0 81 0.0 1.0
Signaling by pdgf 0 35 0.0 1.0
Apc c cdc20 mediated degradation of cyclin b 0 23 0.0 1.0
Telomere extension by telomerase 0 21 0.0 1.0
Transcription of the hiv genome 0 67 0.0 1.0
Hiv transcription elongation 0 42 0.0 1.0
Hiv transcription initiation 0 45 0.0 1.0
Signalling to ras 0 16 0.0 1.0
Terminal pathway of complement 0 1 0.0 1.0
Initial triggering of complement 0 1 0.0 1.0
Complement cascade 0 10 0.0 1.0
Signaling by ntrks 0 102 0.0 1.0
The activation of arylsulfatases 0 8 0.0 1.0
Abortive elongation of hiv 1 transcript in the absence of tat 0 23 0.0 1.0
Mtorc1 mediated signalling 0 23 0.0 1.0
Myd88 independent tlr4 cascade 0 78 0.0 1.0
Glycosphingolipid metabolism 0 33 0.0 1.0
Sphingolipid de novo biosynthesis 0 29 0.0 1.0
Synthesis of pips at the late endosome membrane 0 10 0.0 1.0
Synthesis of pips at the early endosome membrane 0 16 0.0 1.0
Synthesis of pips at the golgi membrane 0 15 0.0 1.0
Synthesis of pips at the plasma membrane 0 47 0.0 1.0
Regulation of cholesterol biosynthesis by srebp srebf 1 55 18.761111111111116 0.0577898017123185
Mtor signalling 0 39 0.0 1.0
Mitochondrial uncoupling 0 1 0.0 1.0
Hiv elongation arrest and recovery 0 32 0.0 1.0
Nef mediated cd4 down regulation 0 7 0.0 1.0
The fatty acid cycling model 0 1 0.0 1.0
P38mapk events 0 13 0.0 1.0
Arms mediated activation 0 5 0.0 1.0
Signaling by tgf beta receptor complex 0 67 0.0 1.0
Regulation of glucokinase by glucokinase regulatory protein 0 31 0.0 1.0
Adenylate cyclase inhibitory pathway 0 6 0.0 1.0
Adenylate cyclase activating pathway 0 3 0.0 1.0
Prolonged erk activation events 0 12 0.0 1.0
Ddx58 ifih1 mediated induction of interferon alpha beta 0 57 0.0 1.0
Ticam1 rip1 mediated ikk complex recruitment 0 16 0.0 1.0
Toll like receptor cascades 0 103 0.0 1.0
Neurotoxicity of clostridium toxins 0 8 0.0 1.0
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0 42 0.0 1.0
Nod1 2 signaling pathway 0 30 0.0 1.0
Viral messenger rna synthesis 0 44 0.0 1.0
Ns1 mediated effects on host pathways 0 40 0.0 1.0
Export of viral ribonucleoproteins from nucleus 0 32 0.0 1.0
Influenza infection 0 150 0.0 1.0
Innate immune system 1 624 1.534831460674157 0.5009447081104751
Toll like receptor tlr1 tlr2 cascade 0 70 0.0 1.0
Toll like receptor 9 tlr9 cascade 0 75 0.0 1.0
Trafficking and processing of endosomal tlr 0 8 0.0 1.0
Alternative complement activation 0 1 0.0 1.0
Collagen biosynthesis and modifying enzymes 0 30 0.0 1.0
Activation of trka receptors 0 1 0.0 1.0
Scf skp2 mediated degradation of p27 p21 0 54 0.0 1.0
Negative regulation of the pi3k akt network 0 62 0.0 1.0
Vitamin b5 pantothenate metabolism 0 13 0.0 1.0
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0 26 0.0 1.0
Erk mapk targets 0 20 0.0 1.0
Nuclear events kinase and transcription factor activation 0 42 0.0 1.0
Akt phosphorylates targets in the nucleus 0 9 0.0 1.0
Akt phosphorylates targets in the cytosol 0 14 0.0 1.0
Pi3k akt activation 0 7 0.0 1.0
Signaling by notch2 0 22 0.0 1.0
Creb phosphorylation 0 7 0.0 1.0
Signaling by notch1 0 56 0.0 1.0
A tetrasaccharide linker sequence is required for gag synthesis 0 16 0.0 1.0
Metabolism of vitamins and cofactors 0 134 0.0 1.0
Metabolism of water soluble vitamins and cofactors 0 91 0.0 1.0
Vitamin b2 riboflavin metabolism 0 4 0.0 1.0
Vitamin c ascorbate metabolism 0 6 0.0 1.0
Vitamin b1 thiamin metabolism 0 5 0.0 1.0
Nicotinate metabolism 0 18 0.0 1.0
Vitamin d calciferol metabolism 0 8 0.0 1.0
Coenzyme a biosynthesis 0 8 0.0 1.0
Nicotinamide salvaging 0 11 0.0 1.0
Er to golgi anterograde transport 0 129 0.0 1.0
Membrane trafficking 0 532 0.0 1.0
Trans golgi network vesicle budding 0 69 0.0 1.0
Erks are inactivated 0 11 0.0 1.0
Calcineurin activates nfat 0 8 0.0 1.0
Generation of second messenger molecules 0 11 0.0 1.0
Cs ds degradation 0 7 0.0 1.0
Hs gag degradation 0 17 0.0 1.0
Tcr signaling 0 85 0.0 1.0
Hs gag biosynthesis 0 17 0.0 1.0
Dermatan sulfate biosynthesis 0 6 0.0 1.0
Chondroitin sulfate biosynthesis 0 12 0.0 1.0
Keratan sulfate degradation 0 6 0.0 1.0
Keratan sulfate biosynthesis 0 11 0.0 1.0
Metabolism of angiotensinogen to angiotensins 0 8 0.0 1.0
Assembly of collagen fibrils and other multimeric structures 0 28 0.0 1.0
Metabolism of nitric oxide nos3 activation and regulation 0 10 0.0 1.0
G protein activation 0 13 0.0 1.0
Formation of the beta catenin tcf transactivating complex 0 38 0.0 1.0
Wnt mediated activation of dvl 0 8 0.0 1.0
Tcf dependent signaling in response to wnt 0 142 0.0 1.0
Signaling by alk 0 19 0.0 1.0
Signaling by bmp 0 15 0.0 1.0
Carnitine metabolism 0 12 0.0 1.0
Biotin transport and metabolism 0 11 0.0 1.0
Ngf independant trka activation 0 1 0.0 1.0
Metabolism of folate and pterines 0 15 0.0 1.0
Pi3k events in erbb2 signaling 0 7 0.0 1.0
Pre notch processing in golgi 0 13 0.0 1.0
Pre notch processing in the endoplasmic reticulum 0 5 0.0 1.0
Gap junction degradation 0 12 0.0 1.0
Transport of connexons to the plasma membrane 0 14 0.0 1.0
Gap junction assembly 0 15 0.0 1.0
Fgfr2b ligand binding and activation 0 2 0.0 1.0
Fgfr2c ligand binding and activation 0 2 0.0 1.0
Fgfr1c ligand binding and activation 0 2 0.0 1.0
Fgfr3b ligand binding and activation 0 1 0.0 1.0
Pre notch expression and processing 0 50 0.0 1.0
Fgfr1b ligand binding and activation 0 2 0.0 1.0
Fgfr2 ligand binding and activation 0 2 0.0 1.0
Fgfr3 ligand binding and activation 0 3 0.0 1.0
Signaling by fgfr 0 57 0.0 1.0
Heme degradation 0 7 0.0 1.0
Heme biosynthesis 1 12 92.49090909090908 0.0128766161439974
Metabolism of porphyrins 1 17 63.55625 0.0181972414506333
Cellular hexose transport 0 6 0.0 1.0
Signalling to p38 via rit and rin 0 3 0.0 1.0
Signalling to erks 0 30 0.0 1.0
Fgfr1 ligand binding and activation 0 2 0.0 1.0
Cholesterol biosynthesis 0 24 0.0 1.0
Snrnp assembly 0 53 0.0 1.0
Synthesis of bile acids and bile salts 0 20 0.0 1.0
Grb2 events in erbb2 signaling 0 7 0.0 1.0
Beta catenin phosphorylation cascade 0 16 0.0 1.0
Pregnenolone biosynthesis 0 8 0.0 1.0
Metabolism of steroid hormones 0 12 0.0 1.0
Signaling by wnt 0 213 0.0 1.0
Rho gtpase effectors 0 246 0.0 1.0
Degradation of beta catenin by the destruction complex 0 77 0.0 1.0
Vegf ligand receptor interactions 0 2 0.0 1.0
Signaling by vegf 0 87 0.0 1.0
Bile acid and bile salt metabolism 0 22 0.0 1.0
Synthesis of bile acids and bile salts via 27 hydroxycholesterol 0 7 0.0 1.0
Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0 5 0.0 1.0
P75 ntr receptor mediated signalling 0 81 0.0 1.0
P75ntr regulates axonogenesis 0 5 0.0 1.0
Regulated proteolysis of p75ntr 0 11 0.0 1.0
P75ntr negatively regulates cell cycle via sc1 0 5 0.0 1.0
Nrage signals death through jnk 0 47 0.0 1.0
P75ntr signals via nf kb 0 14 0.0 1.0
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0 13 0.0 1.0
Estrogen biosynthesis 0 2 0.0 1.0
Androgen biosynthesis 0 2 0.0 1.0
Cobalamin cbl vitamin b12 transport and metabolism 0 13 0.0 1.0
Cell surface interactions at the vascular wall 0 70 0.0 1.0
The role of nef in hiv 1 replication and disease pathogenesis 0 20 0.0 1.0
Nef mediated downregulation of mhc class i complex cell surface expression 0 9 0.0 1.0
Shc1 events in erbb2 signaling 0 13 0.0 1.0
Erythrocytes take up oxygen and release carbon dioxide 0 1 0.0 1.0
Methionine salvage pathway 0 6 0.0 1.0
Erythrocytes take up carbon dioxide and release oxygen 0 4 0.0 1.0
Cross presentation of soluble exogenous antigens endosomes 0 41 0.0 1.0
Endosomal vacuolar pathway 0 10 0.0 1.0
Antigen processing cross presentation 0 77 0.0 1.0
Cross presentation of particulate exogenous antigens phagosomes 0 3 0.0 1.0
Signaling by erbb4 0 36 0.0 1.0
Pi3k events in erbb4 signaling 0 2 0.0 1.0
Constitutive signaling by ligand responsive egfr cancer variants 0 17 0.0 1.0
Regulation of gene expression by hypoxia inducible factor 0 5 0.0 1.0
Signaling by erbb2 in cancer 0 17 0.0 1.0
Signaling by erbb2 0 37 0.0 1.0
Signaling by fgfr in disease 0 48 0.0 1.0
Ros and rns production in phagocytes 0 16 0.0 1.0
Meiotic synapsis 0 31 0.0 1.0
Fertilization 0 3 0.0 1.0
Signaling by nodal 0 12 0.0 1.0
Prolactin receptor signaling 0 9 0.0 1.0
Cellular response to hypoxia 0 59 0.0 1.0
Shc1 events in erbb4 signaling 0 6 0.0 1.0
Nuclear signaling by erbb4 0 18 0.0 1.0
Downregulation of erbb4 signaling 0 7 0.0 1.0
Elevation of cytosolic ca2 levels 0 6 0.0 1.0
Abc transporters in lipid homeostasis 0 7 0.0 1.0
Bmal1 clock npas2 activates circadian gene expression 0 20 0.0 1.0
Rora activates gene expression 0 17 0.0 1.0
Mitochondrial iron sulfur cluster biogenesis 0 12 0.0 1.0
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0 16 0.0 1.0
Transcription of e2f targets under negative control by dream complex 0 19 0.0 1.0
Downregulation of erbb2 erbb3 signaling 0 10 0.0 1.0
Grb7 events in erbb2 signaling 0 2 0.0 1.0
Acrosome reaction and sperm oocyte membrane binding 0 1 0.0 1.0
Sperm motility and taxes 0 1 0.0 1.0
Tandem pore domain potassium channels 0 2 0.0 1.0
Voltage gated potassium channels 0 2 0.0 1.0
Potassium channels 0 15 0.0 1.0
Inwardly rectifying k channels 0 12 0.0 1.0
Spry regulation of fgf signaling 0 14 0.0 1.0
Adaptive immune system 0 504 0.0 1.0
Cytokine signaling in immune system 0 392 0.0 1.0
Mitochondrial protein import 0 59 0.0 1.0
Developmental biology 0 665 0.0 1.0
Interleukin 7 signaling 0 13 0.0 1.0
Antiviral mechanism by ifn stimulated genes 0 73 0.0 1.0
Activation of puma and translocation to mitochondria 0 8 0.0 1.0
Activation of ras in b cells 0 3 0.0 1.0
Gpvi mediated activation cascade 0 21 0.0 1.0
Smac xiap regulated apoptotic response 0 8 0.0 1.0
Apoptotic cleavage of cellular proteins 0 35 0.0 1.0
Cytochrome c mediated apoptotic response 0 13 0.0 1.0
Activation of caspases through apoptosome mediated cleavage 0 6 0.0 1.0
Formation of apoptosome 0 11 0.0 1.0
Release of apoptotic factors from the mitochondria 0 6 0.0 1.0
Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0 8 0.0 1.0
Activation of noxa and translocation to mitochondria 0 5 0.0 1.0
Activation of bad and translocation to mitochondria 0 16 0.0 1.0
Apoptotic factor mediated response 0 20 0.0 1.0
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0 28 0.0 1.0
Displacement of dna glycosylase by apex1 0 8 0.0 1.0
Recognition and association of dna glycosylase with site containing an affected purine 0 16 0.0 1.0
Translesion synthesis by polh 0 20 0.0 1.0
Recognition of dna damage by pcna containing replication complex 0 30 0.0 1.0
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0 41 0.0 1.0
Mapk3 erk1 activation 0 8 0.0 1.0
Intrinsic pathway for apoptosis 0 53 0.0 1.0
Hemostasis 1 361 2.7291666666666665 0.3274820794247526
Apoptosis 0 159 0.0 1.0
Polb dependent long patch base excision repair 0 9 0.0 1.0
Opioid signalling 0 63 0.0 1.0
Pka mediated phosphorylation of creb 0 13 0.0 1.0
Camk iv mediated phosphorylation of creb 0 8 0.0 1.0
Disinhibition of snare formation 0 4 0.0 1.0
Effects of pip2 hydrolysis 0 17 0.0 1.0
Activation of bh3 only proteins 0 29 0.0 1.0
E2f mediated regulation of dna replication 0 23 0.0 1.0
E2f enabled inhibition of pre replication complex formation 0 10 0.0 1.0
Inhibition of replication initiation of damaged dna by rb1 e2f1 0 13 0.0 1.0
Formation of the early elongation complex 0 33 0.0 1.0
Sos mediated signalling 0 7 0.0 1.0
Mapk1 erk2 activation 0 7 0.0 1.0
Raf independent mapk1 3 activation 0 15 0.0 1.0
Irs mediated signalling 0 26 0.0 1.0
Formation of rna pol ii elongation complex 0 58 0.0 1.0
Neuronal system 0 177 0.0 1.0
Transmission across chemical synapses 0 139 0.0 1.0
Neurotransmitter receptors and postsynaptic signal transmission 0 105 0.0 1.0
Neurotransmitter clearance 0 3 0.0 1.0
Neurotransmitter release cycle 0 30 0.0 1.0
Presynaptic depolarization and calcium channel opening 0 4 0.0 1.0
Electric transmission across gap junctions 0 2 0.0 1.0
G protein mediated events 0 40 0.0 1.0
Ca dependent events 0 26 0.0 1.0
Downstream signaling events of b cell receptor bcr 0 71 0.0 1.0
Nef and signal transduction 0 4 0.0 1.0
Apoptosis induced dna fragmentation 0 11 0.0 1.0
Extrinsic pathway of fibrin clot formation 0 1 0.0 1.0
Integration of provirus 0 9 0.0 1.0
Budding and maturation of hiv virion 0 27 0.0 1.0
Hiv life cycle 0 144 0.0 1.0
Sulfur amino acid metabolism 0 22 0.0 1.0
Degradation of cysteine and homocysteine 0 12 0.0 1.0
Sulfide oxidation to sulfate 0 5 0.0 1.0
Irf3 mediated activation of type 1 ifn 0 3 0.0 1.0
Zbp1 dai mediated induction of type i ifns 0 18 0.0 1.0
Gamma carboxylation transport and amino terminal cleavage of proteins 0 5 0.0 1.0
Early phase of hiv life cycle 0 13 0.0 1.0
Removal of aminoterminal propeptides from gamma carboxylated proteins 0 4 0.0 1.0
Activation of matrix metalloproteinases 0 6 0.0 1.0
Transport of mature mrnas derived from intronless transcripts 0 43 0.0 1.0
Transport of the slbp dependant mature mrna 0 36 0.0 1.0
Mitochondrial biogenesis 0 85 0.0 1.0
Metabolism of nucleotides 0 82 0.0 1.0
Gap junction trafficking and regulation 0 28 0.0 1.0
Telomere maintenance 0 74 0.0 1.0
Signaling by notch 0 152 0.0 1.0
Eukaryotic translation elongation 0 89 0.0 1.0
Recycling of bile acids and salts 0 6 0.0 1.0
Golgi cisternae pericentriolar stack reorganization 0 14 0.0 1.0
Synthesis of glycosylphosphatidylinositol gpi 0 12 0.0 1.0
Attachment of gpi anchor to upar 0 7 0.0 1.0
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0 16 0.0 1.0
2 ltr circle formation 0 7 0.0 1.0
Pka activation in glucagon signalling 0 12 0.0 1.0
Signaling by egfr in cancer 0 17 0.0 1.0
Cell cycle 0 613 0.0 1.0
Gamma carboxylation hypusine formation and arylsulfatase activation 0 29 0.0 1.0
Heparan sulfate heparin hs gag metabolism 0 32 0.0 1.0
Keratan sulfate keratin metabolism 0 17 0.0 1.0
Pp2a mediated dephosphorylation of key metabolic factors 0 6 0.0 1.0
Chrebp activates metabolic gene expression 0 8 0.0 1.0
Integration of energy metabolism 0 71 0.0 1.0
Ampk inhibits chrebp transcriptional activation activity 0 7 0.0 1.0
Triglyceride catabolism 0 13 0.0 1.0
Glucagon signaling in metabolic regulation 0 21 0.0 1.0
Pka mediated phosphorylation of key metabolic factors 0 4 0.0 1.0
Formation of atp by chemiosmotic coupling 0 14 0.0 1.0
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0 116 0.0 1.0
Post translational modification synthesis of gpi anchored proteins 0 32 0.0 1.0
Glycosaminoglycan metabolism 0 70 0.0 1.0
Host interactions of hiv factors 0 116 0.0 1.0
Hiv infection 0 213 0.0 1.0
Polo like kinase mediated events 0 16 0.0 1.0
Caspase activation via death receptors in the presence of ligand 0 11 0.0 1.0
Fibronectin matrix formation 0 3 0.0 1.0
Glutathione conjugation 0 21 0.0 1.0
Acyl chain remodeling of cl 0 5 0.0 1.0
Acyl chain remodelling of pc 0 9 0.0 1.0
Reversible hydration of carbon dioxide 0 2 0.0 1.0
Collagen formation 0 44 0.0 1.0
Extracellular matrix organization 0 131 0.0 1.0
Degradation of the extracellular matrix 0 56 0.0 1.0
Reproduction 0 57 0.0 1.0
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0 7 0.0 1.0
Alpha defensins 0 1 0.0 1.0
Acyl chain remodelling of ps 0 9 0.0 1.0
Defensins 0 1 0.0 1.0
Collagen degradation 0 21 0.0 1.0
Regulation of signaling by nodal 0 3 0.0 1.0
Regulation of kit signaling 0 12 0.0 1.0
Signaling by scf kit 0 31 0.0 1.0
The citric acid tca cycle and respiratory electron transport 0 160 0.0 1.0
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0 21 0.0 1.0
Formation of fibrin clot clotting cascade 1 9 127.2125 0.0096716725706127
Common pathway of fibrin clot formation 0 5 0.0 1.0
Intrinsic pathway of fibrin clot formation 1 7 169.65 0.0075297912401724
Translocation of slc2a4 glut4 to the plasma membrane 0 66 0.0 1.0
Acyl chain remodelling of pe 0 8 0.0 1.0
Acyl chain remodeling of dag and tag 0 2 0.0 1.0
Acyl chain remodelling of pi 0 4 0.0 1.0
Glucuronidation 0 4 0.0 1.0
Cytosolic sulfonation of small molecules 0 14 0.0 1.0
Methylation 0 12 0.0 1.0
Phase ii conjugation of compounds 0 53 0.0 1.0
G0 and early g1 0 26 0.0 1.0
Signaling by activin 0 9 0.0 1.0
Cell cell communication 0 79 0.0 1.0
Meiosis 0 54 0.0 1.0
Dag and ip3 signaling 0 30 0.0 1.0
Phospholipid metabolism 1 156 6.470967741935484 0.1560702041933742
Pi metabolism 0 71 0.0 1.0
Inositol phosphate metabolism 0 40 0.0 1.0
Synthesis of pips at the er membrane 0 5 0.0 1.0
Synthesis of pi 0 5 0.0 1.0
Synthesis of pe 0 12 0.0 1.0
Glycerophospholipid biosynthesis 1 86 11.882352941176473 0.0890077655415831
Synthesis of pc 0 22 0.0 1.0
Synthesis of pa 1 25 42.3375 0.026656035141596
Synthesis of pg 0 8 0.0 1.0
Hydrolysis of lpc 0 3 0.0 1.0
Acyl chain remodelling of pg 0 7 0.0 1.0
Elastic fibre formation 0 23 0.0 1.0
Signaling by hippo 0 21 0.0 1.0
Fcgamma receptor fcgr dependent phagocytosis 0 72 0.0 1.0
Fcgr activation 0 5 0.0 1.0
Adrenaline noradrenaline inhibits insulin secretion 0 16 0.0 1.0
Acetylcholine regulates insulin secretion 0 8 0.0 1.0
Crmps in sema3a signaling 0 12 0.0 1.0
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0 10 0.0 1.0
Sema3a pak dependent axon repulsion 0 13 0.0 1.0
Trafficking of ampa receptors 0 20 0.0 1.0
G protein beta gamma signalling 0 22 0.0 1.0
Muscle contraction 0 83 0.0 1.0
Eph ephrin mediated repulsion of cells 0 43 0.0 1.0
Regulation of lipid metabolism by pparalpha 0 95 0.0 1.0
Ephrin signaling 0 17 0.0 1.0
Ephb mediated forward signaling 0 40 0.0 1.0
Prostacyclin signalling through prostacyclin receptor 0 12 0.0 1.0
Signal amplification 0 22 0.0 1.0
Rap1 signalling 0 13 0.0 1.0
G beta gamma signalling through pi3kgamma 0 15 0.0 1.0
Adp signalling through p2y purinoceptor 12 0 13 0.0 1.0
Nitric oxide stimulates guanylate cyclase 0 11 0.0 1.0
Protein folding 0 79 0.0 1.0
Signal regulatory protein family interactions 0 9 0.0 1.0
Epha mediated growth cone collapse 0 23 0.0 1.0
Circadian clock 0 55 0.0 1.0
Free fatty acids regulate insulin secretion 0 8 0.0 1.0
Incretin synthesis secretion and inactivation 0 14 0.0 1.0
Adp signalling through p2y purinoceptor 1 0 17 0.0 1.0
G alpha s signalling events 0 37 0.0 1.0
Cgmp effects 0 7 0.0 1.0
Platelet calcium homeostasis 0 13 0.0 1.0
Reduction of cytosolic ca levels 0 7 0.0 1.0
Platelet homeostasis 0 51 0.0 1.0
Nucleotide like purinergic receptors 0 1 0.0 1.0
P2y receptors 0 1 0.0 1.0
Trafficking of glur2 containing ampa receptors 0 11 0.0 1.0
Other semaphorin interactions 0 7 0.0 1.0
Sema4d induced cell migration and growth cone collapse 0 18 0.0 1.0
Sema4d mediated inhibition of cell attachment and migration 0 8 0.0 1.0
G alpha 12 13 signalling events 0 57 0.0 1.0
G alpha q signalling events 0 66 0.0 1.0
Sumoylation of intracellular receptors 0 18 0.0 1.0
Pcp ce pathway 0 78 0.0 1.0
Ca2 pathway 0 45 0.0 1.0
Sumoylation of sumoylation proteins 0 35 0.0 1.0
Sialic acid metabolism 0 16 0.0 1.0
Sema4d in semaphorin signaling 0 23 0.0 1.0
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0 9 0.0 1.0
Peroxisomal lipid metabolism 0 24 0.0 1.0
G alpha i signalling events 0 88 0.0 1.0
Diseases associated with o glycosylation of proteins 0 17 0.0 1.0
Association of tric cct with target proteins during biosynthesis 0 36 0.0 1.0
Atf6 atf6 alpha activates chaperone genes 0 6 0.0 1.0
Unfolded protein response upr 0 75 0.0 1.0
Ire1alpha activates chaperones 0 44 0.0 1.0
Perk regulates gene expression 0 26 0.0 1.0
Atf6 atf6 alpha activates chaperones 0 8 0.0 1.0
Atf4 activates genes in response to endoplasmic reticulum stress 0 22 0.0 1.0
Energy dependent regulation of mtor by lkb1 ampk 0 27 0.0 1.0
Recruitment of numa to mitotic centrosomes 0 90 0.0 1.0
Recruitment of mitotic centrosome proteins and complexes 0 82 0.0 1.0
Transcriptional regulation of white adipocyte differentiation 0 68 0.0 1.0
Chemokine receptors bind chemokines 0 3 0.0 1.0
Trna aminoacylation 0 43 0.0 1.0
Cytosolic trna aminoacylation 0 24 0.0 1.0
Dopamine clearance from the synaptic cleft 0 2 0.0 1.0
Myoclonic epilepsy of lafora 0 5 0.0 1.0
Diseases of glycosylation 0 76 0.0 1.0
Diseases associated with n glycosylation of proteins 0 18 0.0 1.0
Negative regulation of tcf dependent signaling by wnt ligand antagonists 0 5 0.0 1.0
Deactivation of the beta catenin transactivating complex 0 36 0.0 1.0
Signaling by robo receptors 0 197 0.0 1.0
Mitochondrial trna aminoacylation 0 23 0.0 1.0
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0 56 0.0 1.0
Glucagon like peptide 1 glp1 regulates insulin secretion 0 27 0.0 1.0
Olfactory signaling pathway 0 2 0.0 1.0
Folding of actin by cct tric 0 10 0.0 1.0
Beta oxidation of very long chain fatty acids 0 9 0.0 1.0
Post chaperonin tubulin folding pathway 0 18 0.0 1.0
Formation of tubulin folding intermediates by cct tric 0 21 0.0 1.0
Cooperation of prefoldin and tric cct in actin and tubulin folding 0 28 0.0 1.0
Pd 1 signaling 0 5 0.0 1.0
Sumoylation of transcription cofactors 0 41 0.0 1.0
Beta oxidation of pristanoyl coa 0 7 0.0 1.0
Glyoxylate metabolism and glycine degradation 0 22 0.0 1.0
Alpha oxidation of phytanate 0 6 0.0 1.0
Ctla4 inhibitory signaling 0 17 0.0 1.0
Cd28 dependent vav1 pathway 0 7 0.0 1.0
Cd28 dependent pi3k akt signaling 0 15 0.0 1.0
Cd28 co stimulation 0 24 0.0 1.0
Receptor type tyrosine protein phosphatases 0 11 0.0 1.0
Costimulation by the cd28 family 0 39 0.0 1.0
Beta catenin independent wnt signaling 0 117 0.0 1.0
Nuclear receptor transcription pathway 0 29 0.0 1.0
Abc family proteins mediated transport 0 75 0.0 1.0
Transport of small molecules 1 377 2.608776595744681 0.3394255762218339
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0 12 0.0 1.0
Striated muscle contraction 0 16 0.0 1.0
Dscam interactions 0 9 0.0 1.0
G alpha z signalling events 0 28 0.0 1.0
Netrin mediated repulsion signals 0 5 0.0 1.0
Asparagine n linked glycosylation 0 245 0.0 1.0
Synthesis of dolichyl phosphate 0 5 0.0 1.0
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0 59 0.0 1.0
Type i hemidesmosome assembly 0 9 0.0 1.0
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0 25 0.0 1.0
Aquaporin mediated transport 0 26 0.0 1.0
Smooth muscle contraction 0 28 0.0 1.0
Signal transduction by l1 0 20 0.0 1.0
Interaction between l1 and ankyrins 0 12 0.0 1.0
Synthesis of gdp mannose 0 5 0.0 1.0
Formyl peptide receptors bind formyl peptides and many other ligands 0 3 0.0 1.0
Ras activation upon ca2 influx through nmda receptor 0 13 0.0 1.0
Activation of nmda receptors and postsynaptic events 0 68 0.0 1.0
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0 21 0.0 1.0
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0 7 0.0 1.0
Creb1 phosphorylation through the activation of adenylate cyclase 0 9 0.0 1.0
Na cl dependent neurotransmitter transporters 0 4 0.0 1.0
Zinc influx into cells by the slc39 gene family 0 7 0.0 1.0
Depolymerisation of the nuclear lamina 0 16 0.0 1.0
Binding of tcf lef ctnnb1 to target gene promoters 0 7 0.0 1.0
Rsk activation 0 7 0.0 1.0
Synthesis of udp n acetyl glucosamine 0 8 0.0 1.0
Synthesis of substrates in n glycan biosythesis 0 44 0.0 1.0
Cell extracellular matrix interactions 0 16 0.0 1.0
Ksrp khsrp binds and destabilizes mrna 0 17 0.0 1.0
Regulation of mrna stability by proteins that bind au rich elements 0 79 0.0 1.0
Hur elavl1 binds and stabilizes mrna 0 7 0.0 1.0
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0 17 0.0 1.0
Auf1 hnrnp d0 binds and destabilizes mrna 0 48 0.0 1.0
Butyrate response factor 1 brf1 binds and destabilizes mrna 0 17 0.0 1.0
Activation of the ap 1 family of transcription factors 0 8 0.0 1.0
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0 18 0.0 1.0
Activated tak1 mediates p38 mapk activation 0 20 0.0 1.0
Mapk targets nuclear events mediated by map kinases 0 27 0.0 1.0
Other interleukin signaling 0 12 0.0 1.0
Signaling by interleukins 0 248 0.0 1.0
Interleukin 1 processing 0 3 0.0 1.0
Interleukin 17 signaling 0 57 0.0 1.0
Interleukin 12 family signaling 0 43 0.0 1.0
Neurofascin interactions 0 6 0.0 1.0
Chl1 interactions 0 7 0.0 1.0
Nrcam interactions 0 7 0.0 1.0
Cell junction organization 0 54 0.0 1.0
Interleukin 1 family signaling 0 95 0.0 1.0
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0 7 0.0 1.0
Unblocking of nmda receptors glutamate binding and activation 0 9 0.0 1.0
Dcc mediated attractive signaling 0 13 0.0 1.0
Recycling pathway of l1 0 41 0.0 1.0
Zinc transporters 0 12 0.0 1.0
Arachidonate production from dag 0 4 0.0 1.0
Sodium proton exchangers 0 4 0.0 1.0
Sodium calcium exchangers 0 3 0.0 1.0
Metal ion slc transporters 0 15 0.0 1.0
Slc mediated transmembrane transport 0 101 0.0 1.0
Transport of vitamins nucleosides and related molecules 0 21 0.0 1.0
Transport of inorganic cations anions and amino acids oligopeptides 0 44 0.0 1.0
Bicarbonate transporters 0 4 0.0 1.0
Transport of bile salts and organic acids metal ions and amine compounds 0 32 0.0 1.0
Cation coupled chloride cotransporters 0 4 0.0 1.0
Regulation of insulin secretion 0 48 0.0 1.0
Cell cell junction organization 0 31 0.0 1.0
Nectin necl trans heterodimerization 0 5 0.0 1.0
Glucagon type ligand receptors 0 13 0.0 1.0
Tight junction interactions 0 11 0.0 1.0
Lysosphingolipid and lpa receptors 0 3 0.0 1.0
Ncam1 interactions 0 15 0.0 1.0
Adherens junctions interactions 0 18 0.0 1.0
Role of second messengers in netrin 1 signaling 0 3 0.0 1.0
Caspase activation via dependence receptors in the absence of ligand 0 7 0.0 1.0
Synthesis secretion and deacylation of ghrelin 0 5 0.0 1.0
Small interfering rna sirna biogenesis 0 9 0.0 1.0
Sirt1 negatively regulates rrna expression 0 18 0.0 1.0
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0 27 0.0 1.0
Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0 6 0.0 1.0
Proton coupled monocarboxylate transport 0 4 0.0 1.0
Golgi associated vesicle biogenesis 0 55 0.0 1.0
Lysosome vesicle biogenesis 0 32 0.0 1.0
Platelet sensitization by ldl 0 15 0.0 1.0
Passive transport by aquaporins 0 1 0.0 1.0
Vasopressin regulates renal water homeostasis via aquaporins 0 25 0.0 1.0
Gp1b ix v activation signalling 0 7 0.0 1.0
Mrna decay by 5 to 3 exoribonuclease 0 15 0.0 1.0
Mrna decay by 3 to 5 exoribonuclease 0 16 0.0 1.0
Deadenylation of mrna 0 26 0.0 1.0
Deadenylation dependent mrna decay 0 57 0.0 1.0
Thromboxane signalling through tp receptor 0 15 0.0 1.0
Role of abl in robo slit signaling 0 9 0.0 1.0
Organic anion transporters 0 3 0.0 1.0
Inactivation of cdc42 and rac1 0 8 0.0 1.0
Regulation of commissural axon pathfinding by slit and robo 0 7 0.0 1.0
Activation of rac1 0 12 0.0 1.0
Sphingolipid metabolism 0 62 0.0 1.0
Sodium coupled phosphate cotransporters 0 2 0.0 1.0
Multifunctional anion exchangers 0 3 0.0 1.0
Zinc efflux and compartmentalization by the slc30 family 0 5 0.0 1.0
Peptide ligand binding receptors 0 17 0.0 1.0
Ncam signaling for neurite out growth 0 34 0.0 1.0
L1cam interactions 0 91 0.0 1.0
The retinoid cycle in cones daylight vision 0 1 0.0 1.0
Egfr transactivation by gastrin 0 7 0.0 1.0
Smad2 smad3 smad4 heterotrimer regulates transcription 0 29 0.0 1.0
Downregulation of smad2 3 smad4 transcriptional activity 0 23 0.0 1.0
Transcriptional activity of smad2 smad3 smad4 heterotrimer 0 41 0.0 1.0
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0 14 0.0 1.0
Tgf beta receptor signaling activates smads 0 28 0.0 1.0
Downregulation of tgf beta receptor signaling 0 22 0.0 1.0
Binding and uptake of ligands by scavenger receptors 1 17 63.55625 0.0181972414506333
Visual phototransduction 0 40 0.0 1.0
Dap12 interactions 0 21 0.0 1.0
Synthesis of prostaglandins pg and thromboxanes tx 0 8 0.0 1.0
Abacavir metabolism 0 4 0.0 1.0
Abacavir transport and metabolism 0 6 0.0 1.0
Abacavir transmembrane transport 0 2 0.0 1.0
Hyaluronan uptake and degradation 0 8 0.0 1.0
Integrin cell surface interactions 0 37 0.0 1.0
Activation of ppargc1a pgc 1alpha by phosphorylation 0 8 0.0 1.0
Transcriptional activation of mitochondrial biogenesis 0 51 0.0 1.0
Hyaluronan biosynthesis and export 0 1 0.0 1.0
Scavenging of heme from plasma 0 2 0.0 1.0
Notch2 intracellular domain regulates transcription 0 7 0.0 1.0
Mucopolysaccharidoses 0 9 0.0 1.0
Anchoring fibril formation 0 8 0.0 1.0
Condensation of prometaphase chromosomes 0 11 0.0 1.0
Resolution of sister chromatid cohesion 0 120 0.0 1.0
Activation of the phototransduction cascade 0 2 0.0 1.0
Cohesin loading onto chromatin 0 10 0.0 1.0
Establishment of sister chromatid cohesion 0 11 0.0 1.0
Separation of sister chromatids 0 179 0.0 1.0
Mastl facilitates mitotic progression 0 10 0.0 1.0
Fc epsilon receptor fceri signaling 0 108 0.0 1.0
The canonical retinoid cycle in rods twilight vision 0 4 0.0 1.0
Retinoid cycle disease events 0 2 0.0 1.0
Shc related events triggered by igf1r 0 7 0.0 1.0
Activation of gene expression by srebf srebp 1 42 24.741463414634147 0.0444114041010999
Dap12 signaling 0 19 0.0 1.0
Selenoamino acid metabolism 0 107 0.0 1.0
Metabolism of ingested semet sec mesec into h2se 0 4 0.0 1.0
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0 29 0.0 1.0
Phosphate bond hydrolysis by nudt proteins 0 6 0.0 1.0
Condensation of prophase chromosomes 0 23 0.0 1.0
Crosslinking of collagen fibrils 0 10 0.0 1.0
Constitutive signaling by aberrant pi3k in cancer 0 32 0.0 1.0
Pi3k akt signaling in cancer 0 58 0.0 1.0
Hyaluronan metabolism 0 9 0.0 1.0
The phototransduction cascade 0 12 0.0 1.0
Synthesis of 16 20 hydroxyeicosatetraenoic acids hete 0 1 0.0 1.0
Synthesis of 15 eicosatetraenoic acid derivatives 0 3 0.0 1.0
Pecam1 interactions 0 9 0.0 1.0
Regulation of gene expression in early pancreatic precursor cells 0 3 0.0 1.0
Regulation of gene expression in beta cells 0 12 0.0 1.0
Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0 10 0.0 1.0
Glutamate neurotransmitter release cycle 0 17 0.0 1.0
Metabolism of amine derived hormones 0 1 0.0 1.0
Nf kb is activated and signals survival 0 11 0.0 1.0
P75ntr recruits signalling complexes 0 11 0.0 1.0
Nrif signals cell death from the nucleus 0 14 0.0 1.0
Basigin interactions 0 16 0.0 1.0
Nade modulates death signalling 0 5 0.0 1.0
Linoleic acid la metabolism 0 7 0.0 1.0
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0 12 0.0 1.0
Regulation of pyruvate dehydrogenase pdh complex 0 16 0.0 1.0
Copii mediated vesicle transport 0 55 0.0 1.0
Microrna mirna biogenesis 0 24 0.0 1.0
Nostrin mediated enos trafficking 0 3 0.0 1.0
Enos activation 0 7 0.0 1.0
Yap1 and wwtr1 taz stimulated gene expression 0 10 0.0 1.0
Role of phospholipids in phagocytosis 0 16 0.0 1.0
Cell death signalling via nrage nrif and nade 0 63 0.0 1.0
Tie2 signaling 0 12 0.0 1.0
Gene silencing by rna 0 75 0.0 1.0
Biological oxidations 2 94 24.37922705314009 0.0043816077243596
Arachidonic acid metabolism 0 18 0.0 1.0
Synthesis of 12 eicosatetraenoic acid derivatives 0 2 0.0 1.0
Synthesis of lipoxins lx 0 1 0.0 1.0
Synthesis of leukotrienes lt and eoxins ex 0 4 0.0 1.0
Synthesis of 5 eicosatetraenoic acids 0 3 0.0 1.0
Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet 0 1 0.0 1.0
Mhc class ii antigen presentation 0 100 0.0 1.0
Molecules associated with elastic fibres 0 18 0.0 1.0
Egfr interacts with phospholipase c gamma 0 2 0.0 1.0
Dopamine neurotransmitter release cycle 0 18 0.0 1.0
Prc2 methylates histones and dna 0 23 0.0 1.0
Activated notch1 transmits signal to the nucleus 0 21 0.0 1.0
Notch1 intracellular domain regulates transcription 0 39 0.0 1.0
Epigenetic regulation of gene expression 0 102 0.0 1.0
Cyp2e1 reactions 0 1 0.0 1.0
Xenobiotics 0 4 0.0 1.0
Eicosanoids 0 1 0.0 1.0
Endogenous sterols 0 12 0.0 1.0
Miscellaneous substrates 0 2 0.0 1.0
Phase i functionalization of compounds 2 39 60.94894894894895 0.0007672435614702
Cytochrome p450 arranged by substrate type 0 15 0.0 1.0
Ubiquinol biosynthesis 0 7 0.0 1.0
Interaction with cumulus cells and the zona pellucida 0 1 0.0 1.0
Mitotic metaphase and anaphase 0 225 0.0 1.0
Oxidative stress induced senescence 0 69 0.0 1.0
Hsf1 activation 0 25 0.0 1.0
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0 47 0.0 1.0
Regulation of hsf1 mediated heat shock response 0 76 0.0 1.0
Regulation by c flip 0 10 0.0 1.0
Defects in biotin btn metabolism 0 8 0.0 1.0
Glycogen synthesis 0 11 0.0 1.0
Signaling by tgf beta receptor complex in cancer 0 8 0.0 1.0
Loss of function of smad2 3 in cancer 0 7 0.0 1.0
Nuclear pore complex npc disassembly 0 36 0.0 1.0
Cellular response to heat stress 0 93 0.0 1.0
Detoxification of reactive oxygen species 0 24 0.0 1.0
Defects in cobalamin b12 metabolism 0 10 0.0 1.0
Trp channels 0 7 0.0 1.0
Irf3 mediated induction of type i ifn 0 8 0.0 1.0
Chromatin modifying enzymes 0 210 0.0 1.0
Wnt ligand biogenesis and trafficking 0 9 0.0 1.0
Sumoylation of ubiquitinylation proteins 0 39 0.0 1.0
Sumoylation of transcription factors 0 18 0.0 1.0
Glycogen storage diseases 0 10 0.0 1.0
Processing and activation of sumo 0 10 0.0 1.0
Defects in vitamin and cofactor metabolism 0 18 0.0 1.0
Attenuation phase 0 22 0.0 1.0
Hsf1 dependent transactivation 0 30 0.0 1.0
Notch hlh transcription pathway 0 21 0.0 1.0
Semaphorin interactions 0 48 0.0 1.0
Nephrin family interactions 0 17 0.0 1.0
Netrin 1 signaling 0 33 0.0 1.0
Class b 2 secretin family receptors 0 25 0.0 1.0
Class a 1 rhodopsin like receptors 0 21 0.0 1.0
Signaling by gpcr 0 204 0.0 1.0
P130cas linkage to mapk signaling for integrins 0 9 0.0 1.0
Transcriptional regulation by tp53 0 333 0.0 1.0
Defective b4galt1 causes b4galt1 cdg cdg 2d 0 1 0.0 1.0
Defective ext2 causes exostoses 2 0 11 0.0 1.0
Defective chst6 causes mcdc1 0 1 0.0 1.0
Defective chsy1 causes tpbs 0 4 0.0 1.0
Defective chst14 causes eds musculocontractural type 0 4 0.0 1.0
Defective chst3 causes sedcjd 0 4 0.0 1.0
Defective b4galt7 causes eds progeroid type 0 13 0.0 1.0
Diseases associated with glycosaminoglycan metabolism 0 26 0.0 1.0
Grb2 sos provides linkage to mapk signaling for integrins 0 9 0.0 1.0
Integrin signaling 0 18 0.0 1.0
Amino acid transport across the plasma membrane 0 17 0.0 1.0
Apoptotic cleavage of cell adhesion proteins 0 9 0.0 1.0
Metabolism of polyamines 0 48 0.0 1.0
Rmts methylate histone arginines 0 36 0.0 1.0
Hats acetylate histones 0 90 0.0 1.0
Hdms demethylate histones 0 25 0.0 1.0
Pkmts methylate histone lysines 0 46 0.0 1.0
Fceri mediated ca 2 mobilization 0 20 0.0 1.0
Fceri mediated mapk activation 0 24 0.0 1.0
Role of lat2 ntal lab on calcium mobilization 0 12 0.0 1.0
Signaling by notch1 hd domain mutants in cancer 0 9 0.0 1.0
Eph ephrin signaling 0 80 0.0 1.0
Stimuli sensing channels 0 38 0.0 1.0
Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant 0 4 0.0 1.0
Insulin processing 0 21 0.0 1.0
Caspase mediated cleavage of cytoskeletal proteins 0 12 0.0 1.0
Acetylcholine neurotransmitter release cycle 0 11 0.0 1.0
Fbxw7 mutants and notch1 in cancer 0 5 0.0 1.0
Signaling by notch1 pest domain mutants in cancer 0 45 0.0 1.0
Signaling by leptin 0 8 0.0 1.0
Regulation of plk1 activity at g2 m transition 0 87 0.0 1.0
Cytosolic iron sulfur cluster assembly 0 13 0.0 1.0
Trif mediated programmed cell death 0 4 0.0 1.0
Dna damage telomere stress induced senescence 0 38 0.0 1.0
Oncogene induced senescence 0 30 0.0 1.0
Formation of senescence associated heterochromatin foci sahf 0 15 0.0 1.0
Cellular senescence 0 131 0.0 1.0
Senescence associated secretory phenotype sasp 0 54 0.0 1.0
Fceri mediated nf kb activation 0 68 0.0 1.0
Signaling by the b cell receptor bcr 0 91 0.0 1.0
Pou5f1 oct4 sox2 nanog repress genes related to differentiation 0 6 0.0 1.0
Notch2 activation and transmission of signal to the nucleus 0 16 0.0 1.0
Hdacs deacetylate histones 0 40 0.0 1.0
Regulation of innate immune responses to cytosolic dna 0 11 0.0 1.0
Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0 5 0.0 1.0
Dex h box helicases activate type i ifn and inflammatory cytokines production 0 7 0.0 1.0
Sumoylation of dna damage response and repair proteins 0 76 0.0 1.0
Sumo is proteolytically processed 0 6 0.0 1.0
Sumo is transferred from e1 to e2 ube2i ubc9 0 7 0.0 1.0
Sumo is conjugated to e1 uba2 sae1 0 5 0.0 1.0
Scavenging by class f receptors 0 5 0.0 1.0
Scavenging by class a receptors 0 10 0.0 1.0
Scavenging by class b receptors 1 2 1018.4 0.0021566506862345
Ecm proteoglycans 0 37 0.0 1.0
Non integrin membrane ecm interactions 0 37 0.0 1.0
Syndecan interactions 0 20 0.0 1.0
Laminin interactions 0 23 0.0 1.0
Nuclear envelope ne reassembly 0 71 0.0 1.0
Initiation of nuclear envelope ne reformation 0 20 0.0 1.0
Sumoylation 0 155 0.0 1.0
Activation of nima kinases nek9 nek6 nek7 0 7 0.0 1.0
Nuclear envelope breakdown 0 54 0.0 1.0
Peptide hormone metabolism 0 43 0.0 1.0
Pou5f1 oct4 sox2 nanog activate genes related to proliferation 0 8 0.0 1.0
Ion channel transport 0 82 0.0 1.0