| Term overlap geneset_size odds pval fdr leading_edge |
| Biological oxidations 11 94 5.4692241770429 1.7695267142433475e-05 0.02774617887933569 O00170,O43169,O43488,P00387,P05091,P07099,P21964,P30837,P78417,Q96IU4,Q9NUJ1 |
| The citric acid tca cycle and respiratory electron transport 14 160 3.9818899465985607 3.754092689594118e-05 0.029432086686417887 O00483,O43674,O43678,O43819,O75306,O75380,O75964,P13073,P21796,P47985,P48735,Q13423,Q16795,Q9UDW1 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 11 116 4.3136481370791 0.00012537050157466846 0.05888191155033067 O00483,O43674,O43678,O43819,O75306,O75380,O75964,P13073,P47985,Q16795,Q9UDW1 |
| Protein localization 12 142 3.807110536522301 0.0001877611975456973 0.05888191155033067 O43808,O60830,P09110,P09601,P21796,P46379,P60468,Q13505,Q8NBU5,Q8TB36,Q9NS69,Q9Y276 |
| Respiratory electron transport 10 101 4.512362637362638 0.0001778670943326147 0.05888191155033067 O00483,O43674,O43678,O43819,O75306,O75380,P13073,P47985,Q16795,Q9UDW1 |
| Srp dependent cotranslational protein targeting to membrane 10 108 4.187074829931973 0.0003086309224678178 0.05897834161198756 P04844,P42766,P43307,P60468,P62081,P62269,P62753,P62841,P62847,P62899 |
| Metabolism of lipids 26 508 2.279045643153527 0.00029725061287452385 0.05897834161198756 O43772,O43808,P07602,P09110,P11474,P16278,P23786,P30536,P42126,P48449,P55809,Q03426,Q15392,Q4G176,Q53GQ0,Q6IAN0,Q71SY5,Q8IV08,Q8N8N7,Q8NBJ7,Q8NF37,Q8WUK0,Q96G23,Q9BTU6,Q9BWD1,Q9NZJ7 |
| Metabolism of rna 31 647 2.1439690446539763 0.00024941306477565487 0.05897834161198756 O43148,O60294,O75648,P25787,P38159,P42766,P49720,P49721,P55735,P62081,P62269,P62314,P62753,P62841,P62847,P62875,P62899,Q15366,Q2VPK5,Q969T7,Q96BP3,Q96GA3,Q9BVI4,Q9BWJ5,Q9BZJ0,Q9NPE3,Q9NQT5,Q9NWZ8,Q9UHX1,Q9Y2Z2,Q9Y6V7 |
| Phase i functionalization of compounds 6 39 7.386736214605067 0.0003385236444565613 0.05897834161198756 O00170,O43169,P00387,P05091,P07099,P30837 |
| Infectious disease 28 619 1.996463468544687 0.0012292156401143108 0.19274101236992394 O15143,O43148,O43237,O75530,P04844,P09601,P12931,P14373,P21964,P25787,P42566,P42766,P49720,P49721,P55735,P62081,P62269,P62753,P62841,P62847,P62875,P62879,P62899,P63096,Q13546,Q8WUX9,Q96FJ2,Q9UQB8 |
| Metabolism of amino acids and derivatives 16 281 2.4979196903725205 0.0015093816889900032 0.21515549893966593 O75600,P00966,P25325,P25787,P31937,P42766,P49720,P49721,P62081,P62269,P62753,P62841,P62847,P62899,Q13126,Q9UBX3 |
| Neurotransmitter clearance 2 3 80.20161290322581 0.0017674295866334359 0.23094413265343564 P05091,P21964 |
| Cholesterol biosynthesis 4 24 8.069918699186992 0.0025472603414639686 0.2972519006604974 P48449,Q03426,Q15392,Q9BWD1 |
| Innate immune system 27 624 1.8960497555039773 0.002825550705195905 0.2972519006604974 O15143,P00387,P07602,P09110,P09601,P12931,P16278,P25787,P30519,P42575,P42785,P47755,P49720,P49721,P61916,P62875,Q13546,Q15366,Q6SZW1,Q8IV08,Q8N2G8,Q8NF37,Q93050,Q9BTY2,Q9NZJ7,Q9UQB8,Q9Y315 |
| Asparagine n linked glycosylation 14 245 2.494863893168978 0.002843608743563432 0.2972519006604974 O43237,O60547,P04844,P16278,P24390,P33908,P47755,P55735,Q12907,Q13561,Q2TAA5,Q86YN1,Q96FJ2,Q9UJ70 |
| Signaling by robo receptors 12 197 2.6602770838064957 0.0033460142205935517 0.32790939361816807 O14786,P12931,P25787,P42766,P49720,P49721,P62081,P62269,P62753,P62841,P62847,P62899 |
| Rrna processing 12 202 2.5889429455992925 0.004095739438579563 0.3777717317466326 P42766,P62081,P62269,P62753,P62841,P62847,P62899,Q96GA3,Q9BVI4,Q9NPE3,Q9NQT5,Q9Y6V7 |
| Regulation of expression of slits and robos 10 155 2.8163793103448276 0.004805798842122198 0.41863847691375594 P25787,P42766,P49720,P49721,P62081,P62269,P62753,P62841,P62847,P62899 |
| Cytoprotection by hmox1 8 110 3.1904067412088803 0.005570486733492554 0.44707132088595264 O00483,O43819,P09601,P13073,P25787,P30519,P49720,P49721 |
| Ethanol oxidation 2 5 26.728494623655912 0.005702440317422865 0.44707132088595264 P05091,P30837 |
| Eukaryotic translation elongation 7 89 3.4652213188798555 0.0061211253471970765 0.4570440259240484 P42766,P62081,P62269,P62753,P62841,P62847,P62899 |
| Fatty acid metabolism 8 117 2.9833952536204413 0.00801610773636175 0.4887375658959127 O43772,O43808,P09110,P23786,P42126,Q4G176,Q53GQ0,Q8N8N7 |
| Response of eif2ak4 gcn2 to amino acid deficiency 7 94 3.2644151175441087 0.00820638616503544 0.4887375658959127 P42766,P62081,P62269,P62753,P62841,P62847,P62899 |
| Eukaryotic translation initiation 8 116 3.011325374961739 0.007624708273756434 0.4887375658959127 P42766,P62081,P62269,P62753,P62841,P62847,P62899,Q9NR50 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 4 33 5.560414914493973 0.008258008186469901 0.4887375658959127 O00170,P78417,Q13126,Q53EL6 |
| Glycosphingolipid metabolism 4 33 5.560414914493973 0.008258008186469901 0.4887375658959127 P07602,P16278,Q8NBJ7,Q9NZJ7 |
| Vitamin c ascorbate metabolism 2 6 20.044354838709676 0.008415761657646455 0.4887375658959127 P00387,P78417 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 2 7 16.033870967741937 0.011592504436601331 0.5281388959459786 Q15404,Q9NVD7 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 3 19 7.537955465587045 0.010554648867346124 0.5281388959459786 P09601,P46379,P60468 |
| Influenza infection 9 150 2.5968923810364615 0.011506939263036194 0.5281388959459786 P42766,P55735,P62081,P62269,P62753,P62841,P62847,P62875,P62899 |
| Class i peroxisomal membrane protein import 3 19 7.537955465587045 0.010554648867346124 0.5281388959459786 O43808,Q8NBU5,Q8TB36 |
| Transport of small molecules 17 377 1.9427992370052456 0.011430757176499641 0.5281388959459786 P09601,P21796,P23634,P25787,P30519,P45880,P49720,P49721,P61916,P62879,Q13546,Q15904,Q70HW3,Q8WTV0,Q93050,Q9HD20,Q9UBX3 |
| Heme degradation 2 7 16.033870967741937 0.011592504436601331 0.5281388959459786 P09601,P30519 |
| Complex i biogenesis 5 56 3.9595838335334133 0.011761767734389283 0.5281388959459786 O43674,O43678,O75306,O75380,Q16795 |
| Translation 14 289 2.0861941448382124 0.01178881464165131 0.5281388959459786 O60783,P04844,P42766,P43307,P60468,P62081,P62269,P62753,P62841,P62847,P62899,Q5T653,Q9NR50,Q9P015 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 5 59 3.7384731670445954 0.014533780806367793 0.5697242076096175 O60547,P16278,Q2TAA5,Q86YN1,Q9UJ70 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 5 59 3.7384731670445954 0.014533780806367793 0.5697242076096175 P62081,P62269,P62753,P62841,P62847 |
| Mitochondrial protein import 5 59 3.7384731670445954 0.014533780806367793 0.5697242076096175 O60830,P21796,Q13505,Q9NS69,Q9Y276 |
| Interleukin 12 signaling 4 38 4.740315638450502 0.013545688387651104 0.5697242076096175 O00170,P78417,Q13126,Q53EL6 |
| Iron uptake and transport 4 38 4.740315638450502 0.013545688387651104 0.5697242076096175 P09601,P30519,Q15904,Q93050 |
| Selenoamino acid metabolism 7 107 2.8362962962962963 0.016025882528720732 0.5711041773871388 P42766,P62081,P62269,P62753,P62841,P62847,P62899 |
| Signal amplification 3 22 6.345834221180482 0.015894102382100754 0.5711041773871388 P12931,P62879,P63096 |
| Synthesis of pg 2 8 13.36021505376344 0.015208495533896828 0.5711041773871388 Q8IV08,Q8WUK0 |
| Sulfur amino acid metabolism 3 22 6.345834221180482 0.015894102382100754 0.5711041773871388 P25325,Q13126,Q9UBX3 |
| Cellular response to chemical stress 8 133 2.597289256198347 0.01653615084031837 0.5761929892804267 O00483,O43819,P09601,P13073,P25787,P30519,P49720,P49721 |
| Rrna modification in the nucleus and cytosol 5 63 3.4792399718508094 0.018867674889724653 0.6033808406580872 P62081,P62753,Q9BVI4,Q9NPE3,Q9Y6V7 |
| Trna modification in the mitochondrion 2 9 11.450460829493087 0.019240460480168597 0.6033808406580872 O75648,Q9Y2Z2 |
| Nonsense mediated decay nmd 7 110 2.7528466978305164 0.01839738694256127 0.6033808406580872 P42766,P62081,P62269,P62753,P62841,P62847,P62899 |
| Sphingolipid metabolism 5 62 3.5406373075546007 0.01771340454349872 0.6033808406580872 P07602,P16278,Q8NBJ7,Q96G23,Q9NZJ7 |
| Mucopolysaccharidoses 2 9 11.450460829493087 0.019240460480168597 0.6033808406580872 P16278,P54802 |
| Mitophagy 3 24 5.740312319259687 0.020154545495930827 0.6196534772082262 P12931,P21796,Q9NS69 |
| Cellular response to starvation 8 139 2.4768153428805753 0.020993879710391697 0.6211019506772486 P42766,P55735,P62081,P62269,P62753,P62841,P62847,P62899 |
| Interleukin 12 family signaling 4 43 4.130498228059204 0.02060199203737463 0.6211019506772486 O00170,P78417,Q13126,Q53EL6 |
| Synthesis of substrates in n glycan biosythesis 4 44 4.0268292682926825 0.022238476952830523 0.6457394789266345 O60547,P16278,Q86YN1,Q9UJ70 |
| Copi independent golgi to er retrograde traffic 4 45 3.9282173309537973 0.023952148320753507 0.6595554406854479 O43237,P47755,Q13561,Q96FJ2 |
| Selective autophagy 5 67 3.2534562211981566 0.023976186300427634 0.6595554406854479 O43237,P12931,P21796,Q96FJ2,Q9NS69 |
| E2f enabled inhibition of pre replication complex formation 2 10 10.018145161290322 0.023665994203587892 0.6595554406854479 O43929,P14635 |
| Interconversion of nucleotide di and triphosphates 3 26 5.240098574194684 0.0249818024442509 0.6753701074583692 Q13232,Q9H773,Q9Y3D8 |
| Neutrophil degranulation 14 319 1.8751597666018338 0.02544943407295238 0.676351061464226 P00387,P07602,P09110,P16278,P25787,P30519,P42785,P61916,Q8N2G8,Q8NF37,Q93050,Q9BTY2,Q9NZJ7,Q9Y315 |
| Cristae formation 3 27 5.021255060728745 0.027608043305530176 0.7047888479863142 O75964,Q13505,Q9BUR5 |
| Cellular responses to stimuli 23 614 1.6038298411562573 0.02786792638721396 0.7047888479863142 O00483,O43237,O43819,O75530,P09601,P13073,P25787,P30519,P42766,P43307,P47755,P49720,P49721,P55735,P62081,P62269,P62753,P62841,P62847,P62899,Q13561,Q96FJ2,Q9NQT5 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 4 47 3.744753261486103 0.027613853093999295 0.7047888479863142 O43237,P47755,Q13561,Q96FJ2 |
| Long term potentiation 2 11 8.904121863799283 0.02846353267103837 0.7084257020347328 P12931,Q92796 |
| Transport to the golgi and subsequent modification 8 148 2.315466351829988 0.029187102644984933 0.7150840148021309 O43237,P24390,P33908,P47755,P55735,Q12907,Q13561,Q96FJ2 |
| Metabolism of steroid hormones 2 12 8.012903225806452 0.033612325379231756 0.7750606793328735 P30536,Q53GQ0 |
| Methylation 2 12 8.012903225806452 0.033612325379231756 0.7750606793328735 P21964,P78417 |
| Carnitine metabolism 2 12 8.012903225806452 0.033612325379231756 0.7750606793328735 O43772,P23786 |
| Degradation of cysteine and homocysteine 2 12 8.012903225806452 0.033612325379231756 0.7750606793328735 P25325,Q9UBX3 |
| Transcriptional regulation by runx2 6 100 2.5772584583188003 0.036108549868897014 0.8205537129627611 P11474,P12931,P14635,P25787,P49720,P49721 |
| Er to golgi anterograde transport 7 129 2.3196383997841195 0.03931000530119155 0.8443573741406624 O43237,P24390,P47755,P55735,Q12907,Q13561,Q96FJ2 |
| Tnfr1 induced proapoptotic signaling 2 13 7.2837243401759535 0.039092408683795106 0.8443573741406624 Q13546,Q6GQQ9 |
| Adp signalling through p2y purinoceptor 12 2 13 7.2837243401759535 0.039092408683795106 0.8443573741406624 P62879,P63096 |
| Regulation of runx3 expression and activity 4 52 3.352981029810298 0.038158675177407377 0.8443573741406624 P12931,P25787,P49720,P49721 |
| Phase ii conjugation of compounds 4 53 3.2842210054753607 0.040508503274826094 0.8531711105573013 P21964,P78417,Q96IU4,Q9NUJ1 |
| Metabolism of steroids 6 103 2.496788913300659 0.04080856715038112 0.8531711105573013 P30536,P48449,Q03426,Q15392,Q53GQ0,Q9BWD1 |
| Cdt1 association with the cdc6 orc origin complex 4 54 3.218211382113821 0.0429389108076898 0.8858975282428633 O43929,P25787,P49720,P49721 |
| Dopamine clearance from the synaptic cleft 1 2 39.93975903614458 0.04843998290695995 0.9377023851618914 P21964 |
| Hdl clearance 1 2 39.93975903614458 0.04843998290695995 0.9377023851618914 Q8WTV0 |
| Androgen biosynthesis 1 2 39.93975903614458 0.04843998290695995 0.9377023851618914 Q53GQ0 |
| G2 m checkpoints 7 134 2.2271799358413533 0.046672430929826245 0.9377023851618914 O43929,P14635,P25787,P49720,P49721,Q9NWV8,Q9UQ84 |
| Scavenging by class b receptors 1 2 39.93975903614458 0.04843998290695995 0.9377023851618914 Q8WTV0 |
| Insulin receptor recycling 2 15 6.161910669975186 0.05097037244365778 0.9629101685741613 Q15904,Q93050 |
| Ion channel transport 5 82 2.6156904320169625 0.05063943276888548 0.9629101685741613 P23634,Q13546,Q15904,Q93050,Q9HD20 |
| Cell cycle checkpoints 11 257 1.81481103513964 0.05176798667620508 0.9663357512891615 O43237,O43929,P14635,P25787,P49720,P49721,P55735,Q92674,Q96FJ2,Q9NWV8,Q9UQ84 |
| Regulation of hmox1 expression and activity 4 58 2.9786208973200843 0.053464555112391905 0.9687629714034011 P09601,P25787,P49720,P49721 |
| Gaba b receptor activation 2 16 5.721198156682028 0.05733203109060227 0.9687629714034011 P62879,P63096 |
| Cell extracellular matrix interactions 2 16 5.721198156682028 0.05733203109060227 0.9687629714034011 Q15404,Q9NVD7 |
| Mrna decay by 3 to 5 exoribonuclease 2 16 5.721198156682028 0.05733203109060227 0.9687629714034011 Q969T7,Q9NQT5 |
| Mitochondrial biogenesis 5 85 2.5168367346938774 0.057458518074308865 0.9687629714034011 O75964,P11474,P48735,Q13505,Q9BUR5 |
| Ikk complex recruitment mediated by rip1 2 16 5.721198156682028 0.05733203109060227 0.9687629714034011 Q13546,Q6SZW1 |
| Leishmania infection 6 110 2.327080706179067 0.05322502925447979 0.9687629714034011 O15143,P09601,P12931,P62879,P63096,Q9UQB8 |
| Adrenaline noradrenaline inhibits insulin secretion 2 16 5.721198156682028 0.05733203109060227 0.9687629714034011 P62879,P63096 |
| Activation of kainate receptors upon glutamate binding 2 16 5.721198156682028 0.05733203109060227 0.9687629714034011 P62879,Q92796 |
| Synthesis of very long chain fatty acyl coas 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 Q4G176,Q53GQ0 |
| Keratan sulfate keratin metabolism 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 O43505,P16278 |
| Regulation of runx2 expression and activity 4 61 2.8209955783768366 0.06219595043146689 0.9831127696729381 P11474,P25787,P49720,P49721 |
| Pink1 prkn mediated mitophagy 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 P21796,Q9NS69 |
| Peptide ligand binding receptors 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 P07602,Q9NZJ7 |
| Metabolism of porphyrins 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 P09601,P30519 |
| Adp signalling through p2y purinoceptor 1 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 P12931,P62879 |
| G alpha s signalling events 3 37 3.5408430578709216 0.06144667137948488 0.9831127696729381 P12931,P62879,P63096 |
| Hs gag degradation 2 17 5.339247311827957 0.06395248884352021 0.9831127696729381 P16278,P54802 |
| G alpha i signalling events 5 88 2.4251290877796903 0.06477949452159071 0.986157741843245 P07602,P12931,P62879,P63096,Q9NZJ7 |
| Synthesis of dna 4 117 1.4149219368299877 0.32281193317441026 1.0 O43929,P25787,P49720,P49721 |
| Cyclin d associated events in g1 1 45 0.9037970062066447 0.6735811793023442 1.0 P12931 |
| G1 s specific transcription 0 29 0.0 1.0 1.0 |
| Dna strand elongation 0 35 0.0 1.0 1.0 |
| Lagging strand synthesis 0 23 0.0 1.0 1.0 |
| Abc transporters in lipid homeostasis 0 7 0.0 1.0 1.0 |
| Processive synthesis on the lagging strand 0 17 0.0 1.0 1.0 |
| Polymerase switching 0 16 0.0 1.0 1.0 |
| Switching of origins to a post replicative state 4 85 1.9803272106795142 0.15547122469099 1.0 O43929,P25787,P49720,P49721 |
| Dna replication pre initiation 4 92 1.8215077605321508 0.18914516221936029 1.0 O43929,P25787,P49720,P49721 |
| Activation of the pre replicative complex 1 33 1.2442269076305221 0.559801856438838 1.0 O43929 |
| Dna replication initiation 0 8 0.0 1.0 1.0 |
| Orc1 removal from chromatin 4 65 2.6349460215913636 0.07493077744503769 1.0 O43929,P25787,P49720,P49721 |
| G2 phase 0 4 0.0 1.0 1.0 |
| S phase 4 158 1.0338929363319607 0.5450876932207407 1.0 O43929,P25787,P49720,P49721 |
| Cyclin a b1 b2 associated events during g2 m transition 1 24 1.7326698096734765 0.4492542995146525 1.0 P14635 |
| G2 m dna damage checkpoint 3 66 1.9053402737613263 0.2197757549869858 1.0 P14635,Q9NWV8,Q9UQ84 |
| Dna replication 4 137 1.1997065835320007 0.4341710036528077 1.0 O43929,P25787,P49720,P49721 |
| Lysine catabolism 0 11 0.0 1.0 1.0 |
| Propionyl coa catabolism 0 5 0.0 1.0 1.0 |
| Histidine catabolism 0 3 0.0 1.0 1.0 |
| Branched chain amino acid catabolism 1 22 1.8980684643335246 0.42115518658714335 1.0 P31937 |
| Urea cycle 1 6 7.9847389558232935 0.1384198135311803 1.0 P00966 |
| Galactose catabolism 0 5 0.0 1.0 1.0 |
| Fructose catabolism 0 3 0.0 1.0 1.0 |
| Glucose metabolism 2 80 1.020264681555004 0.5878117897228861 1.0 P55735,Q9UBX3 |
| Pyruvate metabolism 1 26 1.5937349397590361 0.47599457655385613 1.0 P21796 |
| Cell cycle mitotic 13 498 1.070016094653965 0.4489315976500919 1.0 O43237,O43929,O94927,P12931,P14635,P25787,P49720,P49721,P55735,Q13561,Q8WUX9,Q92674,Q96FJ2 |
| Gluconeogenesis 1 25 1.6603078982597055 0.4627901258069825 1.0 Q9UBX3 |
| Glycolysis 1 66 0.6105035526722273 0.8067484836572784 1.0 P55735 |
| Cyclin a cdk2 associated events at s phase entry 3 79 1.5773492435542298 0.30596464988633726 1.0 P25787,P49720,P49721 |
| Raf independent mapk1 3 activation 1 15 2.849110728628801 0.31108300972667774 1.0 Q99956 |
| Mitotic spindle checkpoint 4 111 1.4951751386672745 0.2895333986535309 1.0 O43237,P55735,Q92674,Q96FJ2 |
| G1 s dna damage checkpoints 3 61 2.070640792963842 0.18807354433704168 1.0 P25787,P49720,P49721 |
| Stabilization of p53 3 51 2.5045546558704452 0.12909577846836545 1.0 P25787,P49720,P49721 |
| Mapk1 erk2 activation 0 7 0.0 1.0 1.0 |
| G2 m dna replication checkpoint 1 5 9.981927710843374 0.1167524715539159 1.0 P14635 |
| M phase 11 355 1.284689111608446 0.2550144830892676 1.0 O43237,O94927,P14635,P25787,P49720,P49721,P55735,Q13561,Q8WUX9,Q92674,Q96FJ2 |
| Glycogen breakdown glycogenolysis 0 13 0.0 1.0 1.0 |
| Mitotic telophase cytokinesis 0 13 0.0 1.0 1.0 |
| Cdc6 association with the orc origin complex 1 12 3.6272362175976633 0.25774553170225967 1.0 O43929 |
| Mitotic prophase 2 93 0.8733605104572847 0.6696366518451086 1.0 P14635,P55735 |
| Regulation of tp53 activity through acetylation 0 30 0.0 1.0 1.0 |
| Regulation of tp53 activity through phosphorylation 1 82 0.48911696167385593 0.8704753030699801 1.0 Q9UQ84 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0 13 0.0 1.0 1.0 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0 16 0.0 1.0 1.0 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 1 18 2.3456177651783605 0.3606019508791212 1.0 P14635 |
| Fgfr2 alternative splicing 1 26 1.5937349397590361 0.47599457655385613 1.0 P62875 |
| Tp53 regulates transcription of death receptors and ligands 0 10 0.0 1.0 1.0 |
| Tp53 regulates transcription of caspase activators and caspases 1 8 5.70223752151463 0.1801790130745941 1.0 P42575 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0 11 0.0 1.0 1.0 |
| Tp53 regulates transcription of genes involved in cytochrome c release 0 16 0.0 1.0 1.0 |
| Antimicrobial peptides 0 7 0.0 1.0 1.0 |
| Oncogenic mapk signaling 3 66 1.9053402737613263 0.2197757549869858 1.0 P12931,Q99956,Q9NRY5 |
| Ras signaling downstream of nf1 loss of function variants 0 5 0.0 1.0 1.0 |
| Signaling by braf and raf1 fusions 2 53 1.564674256799494 0.3745777826514135 1.0 P12931,Q9NRY5 |
| Signaling by moderate kinase activity braf mutants 1 36 1.1372346528973034 0.5914976917658876 1.0 P12931 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 0 13 0.0 1.0 1.0 |
| E2f mediated regulation of dna replication 2 23 3.8114439324116742 0.10823534446329469 1.0 O43929,P14635 |
| Choline catabolism 0 4 0.0 1.0 1.0 |
| Tp53 regulates transcription of dna repair genes 1 61 0.6617135207496653 0.7810378001033369 1.0 P62875 |
| Regulation of tp53 activity through association with co factors 0 12 0.0 1.0 1.0 |
| Mitotic prometaphase 7 198 1.4712472798569367 0.21323527442751486 1.0 O43237,O94927,P14635,P55735,Q13561,Q92674,Q96FJ2 |
| Regulation of tp53 activity through methylation 1 16 2.6589022757697456 0.3279997416386323 1.0 Q8N0Z6 |
| Regulation of tp53 expression and degradation 0 33 0.0 1.0 1.0 |
| Sos mediated signalling 0 7 0.0 1.0 1.0 |
| Tryptophan catabolism 0 6 0.0 1.0 1.0 |
| Assembly of the orc complex at the origin of replication 1 20 2.098287888395688 0.39162847837900855 1.0 O43929 |
| Glycerophospholipid catabolism 0 4 0.0 1.0 1.0 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 1 27 1.5322829780661107 0.48887573248844235 1.0 P62879 |
| Pi5p regulates tp53 acetylation 0 9 0.0 1.0 1.0 |
| Intra golgi and retrograde golgi to er traffic 6 181 1.3729742388758783 0.28441071136009544 1.0 O43237,P24390,P33908,P47755,Q13561,Q96FJ2 |
| Retrograde transport at the trans golgi network 0 49 0.0 1.0 1.0 |
| Intra golgi traffic 1 42 0.9702223528259379 0.6482306364536417 1.0 P33908 |
| Formation of the early elongation complex 1 33 1.2442269076305221 0.559801856438838 1.0 P62875 |
| Copi dependent golgi to er retrograde traffic 1 83 0.4831031442844549 0.8736769220313676 1.0 P24390 |
| Formation of the cornified envelope 0 24 0.0 1.0 1.0 |
| Copi mediated anterograde transport 5 89 2.3960155490767736 0.06733094489149716 1.0 O43237,P24390,P47755,Q13561,Q96FJ2 |
| Rna polymerase ii transcribes snrna genes 1 73 0.5507585899152164 0.8377694600101696 1.0 P62875 |
| Pten regulation 5 128 1.6298324207731874 0.20563123781824627 1.0 O75530,P14373,P25787,P49720,P49721 |
| Negative regulation of met activity 1 20 2.098287888395688 0.39162847837900855 1.0 P42566 |
| Met receptor activation 0 4 0.0 1.0 1.0 |
| Signaling by met 2 64 1.2856399583766909 0.46795241671821464 1.0 P12931,P42566 |
| Metabolism of fat soluble vitamins 0 29 0.0 1.0 1.0 |
| Keratinization 0 24 0.0 1.0 1.0 |
| Creatine metabolism 0 6 0.0 1.0 1.0 |
| Formation of rna pol ii elongation complex 1 58 0.696751919960544 0.7640044113333799 1.0 P62875 |
| Pentose phosphate pathway 1 13 3.324631860776439 0.27596662529306126 1.0 Q9Y315 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0 4 0.0 1.0 1.0 |
| Mitochondrial fatty acid beta oxidation 1 33 1.2442269076305221 0.559801856438838 1.0 P42126 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 1 5 9.981927710843374 0.1167524715539159 1.0 P42126 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0 9 0.0 1.0 1.0 |
| Synthesis of ketone bodies 0 6 0.0 1.0 1.0 |
| Rna polymerase iii transcription initiation from type 3 promoter 1 30 1.3733554909292343 0.5256573230515567 1.0 P62875 |
| Rna polymerase iii transcription initiation from type 1 promoter 1 31 1.3274431057563587 0.5373222521600443 1.0 P62875 |
| Platelet aggregation plug formation 1 20 2.098287888395688 0.39162847837900855 1.0 P12931 |
| Response to elevated platelet cytosolic ca2 3 71 1.7643486544415337 0.25246138092126835 1.0 P07602,Q9NUQ9,Q9NZJ7 |
| Platelet activation signaling and aggregation 6 152 1.6505726476532674 0.17006632207881062 1.0 P07602,P12931,P62879,P63096,Q9NUQ9,Q9NZJ7 |
| Tnf signaling 2 39 2.1597646033129902 0.24788465108468175 1.0 Q13546,Q6GQQ9 |
| Platelet adhesion to exposed collagen 0 7 0.0 1.0 1.0 |
| Dissolution of fibrin clot 0 7 0.0 1.0 1.0 |
| Trail signaling 0 6 0.0 1.0 1.0 |
| Fasl cd95l signaling 0 5 0.0 1.0 1.0 |
| Apoptotic execution phase 0 47 0.0 1.0 1.0 |
| Triglyceride biosynthesis 0 7 0.0 1.0 1.0 |
| Fatty acyl coa biosynthesis 2 29 2.9626642771804064 0.15821668919150678 1.0 Q4G176,Q53GQ0 |
| Mrna editing 0 4 0.0 1.0 1.0 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0 6 0.0 1.0 1.0 |
| Processing of capped intronless pre mrna 0 29 0.0 1.0 1.0 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0 5 0.0 1.0 1.0 |
| Beta oxidation of butanoyl coa to acetyl coa 0 5 0.0 1.0 1.0 |
| Ptk6 expression 0 2 0.0 1.0 1.0 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 0 13 0.0 1.0 1.0 |
| Ptk6 regulates cell cycle 0 5 0.0 1.0 1.0 |
| Ptk6 regulates rtks and their effectors akt1 and dok1 0 7 0.0 1.0 1.0 |
| Ptk6 regulates proteins involved in rna processing 0 3 0.0 1.0 1.0 |
| Wax and plasmalogen biosynthesis 1 5 9.981927710843374 0.1167524715539159 1.0 Q6IAN0 |
| Signaling by ptk6 0 36 0.0 1.0 1.0 |
| Erbb2 activates ptk6 signaling 0 3 0.0 1.0 1.0 |
| Gastrin creb signalling pathway via pkc and mapk 0 14 0.0 1.0 1.0 |
| Transport of organic anions 0 3 0.0 1.0 1.0 |
| Advanced glycosylation endproduct receptor signaling 1 9 4.988955823293173 0.20029633215213802 1.0 P47755 |
| Regulation of ifng signaling 0 10 0.0 1.0 1.0 |
| Interferon gamma signaling 0 51 0.0 1.0 1.0 |
| The nlrp3 inflammasome 1 10 4.4341811691209285 0.2199219252501269 1.0 P09601 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0 8 0.0 1.0 1.0 |
| Transport of fatty acids 0 3 0.0 1.0 1.0 |
| Processing of intronless pre mrnas 0 21 0.0 1.0 1.0 |
| Slbp dependent processing of replication dependent histone pre mrnas 0 10 0.0 1.0 1.0 |
| Presynaptic depolarization and calcium channel opening 0 4 0.0 1.0 1.0 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0 5 0.0 1.0 1.0 |
| Irs mediated signalling 0 26 0.0 1.0 1.0 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 1 14 3.068582020389249 0.2937421672442234 1.0 P14635 |
| Insulin receptor signalling cascade 0 31 0.0 1.0 1.0 |
| Pyrimidine catabolism 0 6 0.0 1.0 1.0 |
| Pyrimidine salvage 0 9 0.0 1.0 1.0 |
| Transport of nucleotide sugars 0 4 0.0 1.0 1.0 |
| Neurotransmitter release cycle 0 30 0.0 1.0 1.0 |
| Recycling of eif2 gdp 1 8 5.70223752151463 0.1801790130745941 1.0 Q9NR50 |
| Neurotransmitter receptors and postsynaptic signal transmission 4 105 1.584963374386219 0.256792622330016 1.0 P12931,P62879,P63096,Q92796 |
| Transmission across chemical synapses 6 139 1.8143103660791322 0.1265659867651857 1.0 P05091,P12931,P21964,P62879,P63096,Q92796 |
| Neuronal system 6 177 1.405665803853897 0.2675878681061 1.0 P05091,P12931,P21964,P62879,P63096,Q92796 |
| Trna processing 5 109 1.9313186813186813 0.12953827355179293 1.0 O60294,O75648,P55735,Q2VPK5,Q9Y2Z2 |
| Processing of capped intron containing pre mrna 9 239 1.5775572794515604 0.133509174249636 1.0 P38159,P55735,P62314,P62875,Q15366,Q96BP3,Q9BWJ5,Q9BZJ0,Q9UHX1 |
| Transport of mature transcript to cytoplasm 1 81 0.49528112449799194 0.8671928728330457 1.0 P55735 |
| Mrna editing c to u conversion 0 2 0.0 1.0 1.0 |
| Mrna splicing 8 188 1.7935720844811753 0.09134834242709161 1.0 P38159,P62314,P62875,Q15366,Q96BP3,Q9BWJ5,Q9BZJ0,Q9UHX1 |
| Mrna splicing minor pathway 3 52 2.4531934231182353 0.1346633562208347 1.0 P62314,P62875,Q9BWJ5 |
| Mrna capping 2 29 2.9626642771804064 0.15821668919150678 1.0 O43148,P62875 |
| Pyruvate metabolism and citric acid tca cycle 3 48 2.6723346828609986 0.11291463467421847 1.0 P21796,P48735,Q13423 |
| Citric acid cycle tca cycle 2 21 4.213497453310696 0.09270379205394921 1.0 P48735,Q13423 |
| Metabolism of carbohydrates 6 201 1.2296343001261034 0.3711362750259567 1.0 O43505,P16278,P54802,P55735,Q9UBX3,Q9Y315 |
| Protein protein interactions at synapses 1 46 0.8836233824185632 0.6816202597135863 1.0 Q92796 |
| Rna polymerase i transcription initiation 1 49 0.8281459170013387 0.7045733708515651 1.0 P62875 |
| Signaling by insulin receptor 2 45 1.8572768192048013 0.3027256215831923 1.0 Q15904,Q93050 |
| Rna polymerase i promoter escape 1 42 0.9702223528259379 0.6482306364536417 1.0 P62875 |
| Purine ribonucleoside monophosphate biosynthesis 0 11 0.0 1.0 1.0 |
| Signal attenuation 0 9 0.0 1.0 1.0 |
| Irs activation 0 4 0.0 1.0 1.0 |
| Purine catabolism 0 14 0.0 1.0 1.0 |
| Purine salvage 0 12 0.0 1.0 1.0 |
| Ketone body metabolism 1 7 6.653279785809906 0.15955769838061679 1.0 P55809 |
| Rna polymerase iii transcription 1 44 0.924908938077893 0.6653399447031942 1.0 P62875 |
| Rna polymerase iii transcription termination 1 24 1.7326698096734765 0.4492542995146525 1.0 P62875 |
| Dna damage reversal 1 8 5.70223752151463 0.1801790130745941 1.0 Q6P6C2 |
| Resolution of abasic sites ap sites 0 41 0.0 1.0 1.0 |
| Base excision repair ap site formation 0 23 0.0 1.0 1.0 |
| Dna repair 6 291 0.8335634167385677 0.7232563245840262 1.0 O94782,P62875,Q6P6C2,Q99504,Q9NWV8,Q9UQ84 |
| Dna damage bypass 1 49 0.8281459170013387 0.7045733708515651 1.0 O94782 |
| Death receptor signalling 3 120 1.020346724800166 0.5676950242182344 1.0 P42575,Q13546,Q6GQQ9 |
| Chromosome maintenance 3 100 1.233231770942026 0.445802949640595 1.0 P62875,Q92674,Q9NPE3 |
| Base excision repair 0 55 0.0 1.0 1.0 |
| Rna polymerase i transcription 1 63 0.6402383728462236 0.7917073692554857 1.0 P62875 |
| Rna polymerase i transcription termination 1 32 1.2844928099494752 0.548701439263177 1.0 P62875 |
| Rna polymerase ii transcription 16 969 0.6452318813284186 0.9700141097556102 1.0 O00483,O43148,O43819,O75530,P11474,P12931,P13073,P14635,P25787,P42575,P49720,P49721,P62875,Q71SY5,Q8N0Z6,Q9UQ84 |
| Rna polymerase ii transcription termination 0 66 0.0 1.0 1.0 |
| Rna polymerase iii chain elongation 1 19 2.21508255243195 0.37630734606811034 1.0 P62875 |
| Neurexins and neuroligins 1 28 1.475383013535624 0.5014414780701414 1.0 Q92796 |
| Activation of bh3 only proteins 1 29 1.4225473321858864 0.5136995062503719 1.0 Q96FJ2 |
| Tp53 regulates transcription of cell cycle genes 1 43 0.9470262000382482 0.6568914933439602 1.0 P14635 |
| Constitutive signaling by egfrviii 0 14 0.0 1.0 1.0 |
| Gli proteins bind promoters of hh responsive genes to promote transcription 0 2 0.0 1.0 1.0 |
| Activation of smo 0 11 0.0 1.0 1.0 |
| Tp53 regulates transcription of cell death genes 1 34 1.2064013630278692 0.5706303062959026 1.0 P42575 |
| Regulation of tp53 activity 2 146 0.5489471326164874 0.8773135709984251 1.0 Q8N0Z6,Q9UQ84 |
| Hedgehog on state 3 70 1.7908634962837633 0.2458623134324377 1.0 P25787,P49720,P49721 |
| Ligand receptor interactions 0 2 0.0 1.0 1.0 |
| Tp53 regulates metabolic genes 3 84 1.479232268705953 0.3396856282727292 1.0 O00483,O43819,P13073 |
| Rho gtpases activate paks 0 19 0.0 1.0 1.0 |
| Rho gtpases activate rocks 0 19 0.0 1.0 1.0 |
| Tnfr1 mediated ceramide production 0 3 0.0 1.0 1.0 |
| Rho gtpases activate iqgaps 0 26 0.0 1.0 1.0 |
| Rho gtpases activate ktn1 0 11 0.0 1.0 1.0 |
| Rho gtpases activate cit 0 18 0.0 1.0 1.0 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0 14 0.0 1.0 1.0 |
| Rho gtpases activate pkns 0 40 0.0 1.0 1.0 |
| Trafficking of myristoylated proteins to the cilium 0 4 0.0 1.0 1.0 |
| Cd209 dc sign signaling 0 18 0.0 1.0 1.0 |
| C type lectin receptors clrs 4 100 1.668360433604336 0.23013536291808717 1.0 P12931,P25787,P49720,P49721 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0 7 0.0 1.0 1.0 |
| Dectin 2 family 0 4 0.0 1.0 1.0 |
| Pcna dependent long patch base excision repair 0 24 0.0 1.0 1.0 |
| Vesicle mediated transport 14 546 1.0497323818019626 0.47110679572845804 1.0 O43237,P12931,P24390,P33908,P42566,P47755,P55735,Q12907,Q13492,Q13561,Q8WTV0,Q8WUX9,Q96FJ2,Q9NVZ3 |
| Negative regulation of fgfr2 signaling 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Negative regulation of fgfr1 signaling 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Pi 3k cascade fgfr4 0 8 0.0 1.0 1.0 |
| Shc mediated cascade fgfr4 0 8 0.0 1.0 1.0 |
| Downstream signaling of activated fgfr4 0 14 0.0 1.0 1.0 |
| Frs mediated fgfr4 signaling 0 9 0.0 1.0 1.0 |
| Pi 3k cascade fgfr3 0 8 0.0 1.0 1.0 |
| Downstream signaling of activated fgfr3 0 14 0.0 1.0 1.0 |
| Frs mediated fgfr3 signaling 0 9 0.0 1.0 1.0 |
| Shc mediated cascade fgfr3 0 8 0.0 1.0 1.0 |
| Frs mediated fgfr2 signaling 0 9 0.0 1.0 1.0 |
| Downstream signaling of activated fgfr2 0 14 0.0 1.0 1.0 |
| Pi 3k cascade fgfr2 0 8 0.0 1.0 1.0 |
| Frs mediated fgfr1 signaling 0 9 0.0 1.0 1.0 |
| Pi 3k cascade fgfr1 0 8 0.0 1.0 1.0 |
| Shc mediated cascade fgfr1 0 8 0.0 1.0 1.0 |
| Downstream signaling of activated fgfr1 0 15 0.0 1.0 1.0 |
| Phospholipase c mediated cascade fgfr4 0 3 0.0 1.0 1.0 |
| Phospholipase c mediated cascade fgfr2 0 3 0.0 1.0 1.0 |
| Fructose metabolism 0 5 0.0 1.0 1.0 |
| Negative regulation of fgfr3 signaling 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Pyroptosis 1 16 2.6589022757697456 0.3279997416386323 1.0 Q8WUX9 |
| Bbsome mediated cargo targeting to cilium 0 18 0.0 1.0 1.0 |
| Cardiac conduction 1 43 0.9470262000382482 0.6568914933439602 1.0 P23634 |
| Phase 3 rapid repolarisation 0 1 0.0 1.0 1.0 |
| Phase 4 resting membrane potential 0 2 0.0 1.0 1.0 |
| Downstream signaling events of b cell receptor bcr 3 71 1.7643486544415337 0.25246138092126835 1.0 P25787,P49720,P49721 |
| Organic cation anion zwitterion transport 0 3 0.0 1.0 1.0 |
| Organic cation transport 0 3 0.0 1.0 1.0 |
| Aflatoxin activation and detoxification 1 6 7.9847389558232935 0.1384198135311803 1.0 O43488 |
| Diseases of mismatch repair mmr 0 5 0.0 1.0 1.0 |
| Negative regulation of tcf dependent signaling by dvl interacting proteins 0 5 0.0 1.0 1.0 |
| Mitochondrial translation 3 93 1.3300944669365722 0.3999652498667451 1.0 O60783,Q5T653,Q9P015 |
| Ra biosynthesis pathway 1 9 4.988955823293173 0.20029633215213802 1.0 Q8NBN7 |
| Release of hh np from the secreting cell 0 2 0.0 1.0 1.0 |
| Signaling by retinoic acid 1 26 1.5937349397590361 0.47599457655385613 1.0 Q8NBN7 |
| Mismatch repair 1 17 2.4924698795180724 0.34450269493005076 1.0 Q9UQ84 |
| Synthesis of diphthamide eef2 0 8 0.0 1.0 1.0 |
| Signaling by hedgehog 3 122 1.0029939101146532 0.5789646053767982 1.0 P25787,P49720,P49721 |
| Hedgehog ligand biogenesis 3 53 2.4038866396761134 0.14031264739793226 1.0 P25787,P49720,P49721 |
| Tnfr1 induced nfkappab signaling pathway 2 28 3.076923076923077 0.14960060163762684 1.0 Q13546,Q6GQQ9 |
| Regulation of tnfr1 signaling 2 31 2.757786429365962 0.1757094500446031 1.0 Q13546,Q6GQQ9 |
| Phase 0 rapid depolarisation 0 6 0.0 1.0 1.0 |
| Intraflagellar transport 2 48 1.7356241234221599 0.3299370460914438 1.0 Q96FJ2,Q9Y547 |
| Phase 2 plateau phase 0 3 0.0 1.0 1.0 |
| Physiological factors 0 6 0.0 1.0 1.0 |
| Cargo trafficking to the periciliary membrane 0 43 0.0 1.0 1.0 |
| Vxpx cargo targeting to cilium 0 18 0.0 1.0 1.0 |
| Anchoring of the basal body to the plasma membrane 2 95 0.8544051335414499 0.6809932763868034 1.0 O94927,Q13561 |
| Disorders of transmembrane transporters 4 115 1.4407090016846114 0.3116771604441062 1.0 P25787,P49720,P49721,P55735 |
| Slc transporter disorders 1 54 0.7496400697128135 0.7392235469698557 1.0 P55735 |
| Abc transporter disorders 3 61 2.070640792963842 0.18807354433704168 1.0 P25787,P49720,P49721 |
| Cilium assembly 4 183 0.8872235091065994 0.6609132254167766 1.0 O94927,Q13561,Q96FJ2,Q9Y547 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 2 60 1.3748609566184649 0.4349027977407559 1.0 O75530,P62875 |
| Hedgehog off state 3 96 1.2867963954551391 0.4197584001771729 1.0 P25787,P49720,P49721 |
| Degradation of gli1 by the proteasome 3 53 2.4038866396761134 0.14031264739793226 1.0 P25787,P49720,P49721 |
| Diseases associated with glycosylation precursor biosynthesis 1 16 2.6589022757697456 0.3279997416386323 1.0 P16278 |
| Clec7a dectin 1 signaling 4 85 1.9803272106795142 0.15547122469099 1.0 P12931,P25787,P49720,P49721 |
| Clec7a dectin 1 induces nfat activation 0 10 0.0 1.0 1.0 |
| Dectin 1 mediated noncanonical nf kb signaling 3 53 2.4038866396761134 0.14031264739793226 1.0 P25787,P49720,P49721 |
| Irak4 deficiency tlr2 4 0 4 0.0 1.0 1.0 |
| Ikba variant leads to eda id 0 7 0.0 1.0 1.0 |
| Piwi interacting rna pirna biogenesis 1 16 2.6589022757697456 0.3279997416386323 1.0 P62875 |
| Metabolic disorders of biological oxidation enzymes 0 13 0.0 1.0 1.0 |
| Ion homeostasis 1 31 1.3274431057563587 0.5373222521600443 1.0 P23634 |
| Transcriptional regulation by small rnas 2 57 1.4502932551319647 0.4094079381471642 1.0 P55735,P62875 |
| Rrna modification in the mitochondrion 0 6 0.0 1.0 1.0 |
| Negative regulation of fgfr4 signaling 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Signaling by fgfr2 2 51 1.6288676761026992 0.35685011838570857 1.0 P12931,P62875 |
| Post translational protein modification 29 1003 1.2087487340537226 0.19805568016502997 1.0 O43237,O43505,O60547,O60725,P04844,P14373,P16278,P21796,P24390,P25787,P33908,P45880,P47755,P49720,P49721,P52739,P55735,Q12907,Q13546,Q13561,Q2TAA5,Q6GQQ9,Q86YN1,Q8NB78,Q8NBJ7,Q96FJ2,Q9BTY2,Q9NWV8,Q9UJ70 |
| Dual incision in gg ner 0 42 0.0 1.0 1.0 |
| Global genome nucleotide excision repair gg ner 0 87 0.0 1.0 1.0 |
| Nucleotide excision repair 1 114 0.349468671144756 0.9419268600910586 1.0 P62875 |
| Gap filling dna repair synthesis and ligation in gg ner 0 28 0.0 1.0 1.0 |
| Formation of incision complex in gg ner 0 42 0.0 1.0 1.0 |
| Dna damage recognition in gg ner 0 37 0.0 1.0 1.0 |
| Cargo concentration in the er 1 23 1.8116100766703176 0.4353788157626653 1.0 Q12907 |
| Processing of dna double strand break ends 2 66 1.245211693548387 0.484043289924479 1.0 Q9NWV8,Q9UQ84 |
| Dna double strand break response 2 49 1.6985243651338366 0.3389463545945907 1.0 Q99504,Q9NWV8 |
| Homologous dna pairing and strand exchange 1 41 0.994578313253012 0.6393520558322405 1.0 Q9UQ84 |
| Nonhomologous end joining nhej 1 41 0.994578313253012 0.6393520558322405 1.0 Q9NWV8 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 1 26 1.5937349397590361 0.47599457655385613 1.0 Q9UQ84 |
| Sensing of dna double strand breaks 0 6 0.0 1.0 1.0 |
| Homology directed repair 2 106 0.763182382133995 0.7378607050236965 1.0 Q9NWV8,Q9UQ84 |
| Resolution of d loop structures 1 32 1.2844928099494752 0.548701439263177 1.0 Q9UQ84 |
| Dna double strand break repair 3 137 0.8893588736479545 0.6574151348249575 1.0 Q99504,Q9NWV8,Q9UQ84 |
| Cd22 mediated bcr regulation 0 2 0.0 1.0 1.0 |
| Metalloprotease dubs 1 20 2.098287888395688 0.39162847837900855 1.0 Q9NWV8 |
| Deposition of new cenpa containing nucleosomes at the centromere 1 34 1.2064013630278692 0.5706303062959026 1.0 Q92674 |
| Ovarian tumor domain proteases 2 34 2.4984879032258065 0.2024630111897534 1.0 Q13546,Q6GQQ9 |
| Disinhibition of snare formation 0 4 0.0 1.0 1.0 |
| Presynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 1.0 |
| Synaptic adhesion like molecules 1 11 3.9903614457831327 0.23906776451302655 1.0 Q92796 |
| Il 6 type cytokine receptor ligand interactions 0 6 0.0 1.0 1.0 |
| Gdp fucose biosynthesis 1 6 7.9847389558232935 0.1384198135311803 1.0 O60547 |
| Effects of pip2 hydrolysis 0 17 0.0 1.0 1.0 |
| Interleukin 4 and interleukin 13 signaling 1 40 1.020183297291731 0.6302503007248048 1.0 P09601 |
| Erbb2 regulates cell motility 0 6 0.0 1.0 1.0 |
| Trna processing in the mitochondrion 0 5 0.0 1.0 1.0 |
| Trna processing in the nucleus 1 60 0.6729970730379143 0.7755006212469995 1.0 P55735 |
| Interleukin 10 signaling 0 6 0.0 1.0 1.0 |
| Interleukin 6 family signaling 0 10 0.0 1.0 1.0 |
| Fanconi anemia pathway 1 36 1.1372346528973034 0.5914976917658876 1.0 O94782 |
| Synthesis of wybutosine at g37 of trna phe 1 6 7.9847389558232935 0.1384198135311803 1.0 O60294 |
| Trna modification in the nucleus and cytosol 3 43 3.0078947368421054 0.0878701351278624 1.0 O60294,O75648,Q2VPK5 |
| Dual incision in tc ner 1 67 0.6011926493854205 0.8115177708405034 1.0 P62875 |
| Transcription coupled nucleotide excision repair tc ner 1 82 0.48911696167385593 0.8704753030699801 1.0 P62875 |
| Formation of tc ner pre incision complex 1 53 0.7641334569045413 0.7326336234518783 1.0 P62875 |
| Highly calcium permeable nicotinic acetylcholine receptors 0 2 0.0 1.0 1.0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 1.0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors 0 1 0.0 1.0 1.0 |
| Inflammasomes 1 12 3.6272362175976633 0.25774553170225967 1.0 P09601 |
| Signaling by fgfr1 1 28 1.475383013535624 0.5014414780701414 1.0 P12931 |
| Ub specific processing proteases 6 151 1.6621254946297344 0.16651679942156522 1.0 P21796,P25787,P45880,P49720,P49721,Q13546 |
| Uch proteinases 4 79 2.1400542005420053 0.12863209279328225 1.0 P25787,P49720,P49721,Q8NB78 |
| Rho gtpases activate rhotekin and rhophilins 0 8 0.0 1.0 1.0 |
| Rho gtpases activate formins 5 133 1.5653698979591837 0.227750450867556 1.0 O43237,P12931,P55735,Q92674,Q96FJ2 |
| Rho gtpases activate wasps and waves 2 33 2.579344432882414 0.19348808961618394 1.0 O15143,Q9UQB8 |
| Gpvi mediated activation cascade 0 21 0.0 1.0 1.0 |
| Diseases of signal transduction by growth factor receptors and second messengers 8 333 0.9786141131595677 0.5744209263923574 1.0 P12931,P25787,P49720,P49721,P62753,P62875,Q99956,Q9NRY5 |
| Diseases of carbohydrate metabolism 2 23 3.8114439324116742 0.10823534446329469 1.0 P16278,P54802 |
| Formation of xylulose 5 phosphate 0 5 0.0 1.0 1.0 |
| Metallothioneins bind metals 0 2 0.0 1.0 1.0 |
| Clec7a inflammasome pathway 0 4 0.0 1.0 1.0 |
| Response to metal ions 0 5 0.0 1.0 1.0 |
| Fgfrl1 modulation of fgfr1 signaling 0 2 0.0 1.0 1.0 |
| Regulation of ras by gaps 3 57 2.2249212775528564 0.16366424516487182 1.0 P25787,P49720,P49721 |
| Termination of translesion dna synthesis 0 34 0.0 1.0 1.0 |
| Translesion synthesis by polk 0 17 0.0 1.0 1.0 |
| Signaling by fgfr1 in disease 0 29 0.0 1.0 1.0 |
| Signaling by fgfr4 in disease 0 11 0.0 1.0 1.0 |
| Signaling by fgfr2 in disease 1 28 1.475383013535624 0.5014414780701414 1.0 P62875 |
| Signaling by fgfr4 1 26 1.5937349397590361 0.47599457655385613 1.0 P12931 |
| Signaling by fgfr3 1 27 1.5322829780661107 0.48887573248844235 1.0 P12931 |
| Tnfr2 non canonical nf kb pathway 3 58 2.1842473316157527 0.16967513734617123 1.0 P25787,P49720,P49721 |
| Josephin domain dubs 0 9 0.0 1.0 1.0 |
| Rho gtpases activate nadph oxidases 0 13 0.0 1.0 1.0 |
| Tnfs bind their physiological receptors 0 1 0.0 1.0 1.0 |
| Deubiquitination 9 221 1.7146715728489783 0.09394080073249866 1.0 P21796,P25787,P45880,P49720,P49721,Q13546,Q6GQQ9,Q8NB78,Q9NWV8 |
| Diseases associated with surfactant metabolism 0 1 0.0 1.0 1.0 |
| Mapk6 mapk4 signaling 3 77 1.6203085676769888 0.29250483836522556 1.0 P25787,P49720,P49721 |
| Regulation of tlr by endogenous ligand 0 3 0.0 1.0 1.0 |
| Hdr through homologous recombination hrr 1 66 0.6105035526722273 0.8067484836572784 1.0 Q9UQ84 |
| Hdr through mmej alt nhej 0 11 0.0 1.0 1.0 |
| Hdr through single strand annealing ssa 1 35 1.1708008504606662 0.5811934260914344 1.0 Q9UQ84 |
| Map3k8 tpl2 dependent mapk1 3 activation 0 14 0.0 1.0 1.0 |
| Surfactant metabolism 0 8 0.0 1.0 1.0 |
| Mapk family signaling cascades 9 212 1.79234715777855 0.07711609196924302 1.0 O60725,P12931,P18433,P25787,P49720,P49721,Q92796,Q99956,Q9Y4G8 |
| Lgi adam interactions 0 5 0.0 1.0 1.0 |
| Defective cftr causes cystic fibrosis 3 54 2.356513455584663 0.14604051425702808 1.0 P25787,P49720,P49721 |
| Protein repair 0 5 0.0 1.0 1.0 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 0 5 0.0 1.0 1.0 |
| Negative regulation of mapk pathway 1 36 1.1372346528973034 0.5914976917658876 1.0 Q99956 |
| Negative feedback regulation of mapk pathway 0 6 0.0 1.0 1.0 |
| Constitutive signaling by akt1 e17k in cancer 0 25 0.0 1.0 1.0 |
| Map2k and mapk activation 1 31 1.3274431057563587 0.5373222521600443 1.0 P12931 |
| Raf activation 1 33 1.2442269076305221 0.559801856438838 1.0 P12931 |
| Diseases of metabolism 5 131 1.5905409782960804 0.21881708148323703 1.0 O43505,P16278,P54802,Q2TAA5,Q96EY8 |
| Phosphate bond hydrolysis by ntpdase proteins 0 4 0.0 1.0 1.0 |
| Signaling by fgfr2 iiia tm 1 18 2.3456177651783605 0.3606019508791212 1.0 P62875 |
| Programmed cell death 6 179 1.3891310527811997 0.2759684145462716 1.0 P25787,P49720,P49721,Q13546,Q8WUX9,Q96FJ2 |
| Foxo mediated transcription of cell cycle genes 0 13 0.0 1.0 1.0 |
| Regulation of foxo transcriptional activity by acetylation 0 10 0.0 1.0 1.0 |
| Negative regulation of nmda receptor mediated neuronal transmission 1 14 3.068582020389249 0.2937421672442234 1.0 Q92796 |
| Transcriptional regulation of granulopoiesis 0 34 0.0 1.0 1.0 |
| Postmitotic nuclear pore complex npc reformation 1 27 1.5322829780661107 0.48887573248844235 1.0 P55735 |
| Late endosomal microautophagy 1 29 1.4225473321858864 0.5136995062503719 1.0 Q8WUX9 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0 18 0.0 1.0 1.0 |
| Foxo mediated transcription of cell death genes 0 12 0.0 1.0 1.0 |
| Regulation of localization of foxo transcription factors 0 13 0.0 1.0 1.0 |
| Foxo mediated transcription 0 47 0.0 1.0 1.0 |
| Chaperone mediated autophagy 0 16 0.0 1.0 1.0 |
| Lipophagy 0 8 0.0 1.0 1.0 |
| Autophagy 6 130 1.947778952934955 0.1001072891119571 1.0 O43237,P12931,P21796,Q8WUX9,Q96FJ2,Q9NS69 |
| Hcmv late events 2 62 1.3287634408602151 0.45156828371782387 1.0 P55735,Q8WUX9 |
| Assembly and cell surface presentation of nmda receptors 1 28 1.475383013535624 0.5014414780701414 1.0 Q92796 |
| Hcmv early events 4 79 2.1400542005420053 0.12863209279328225 1.0 O43237,O75530,P55735,Q96FJ2 |
| Hcmv infection 5 102 2.0721649484536084 0.10543075550334358 1.0 O43237,O75530,P55735,Q8WUX9,Q96FJ2 |
| Polb dependent long patch base excision repair 0 9 0.0 1.0 1.0 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 0 28 0.0 1.0 1.0 |
| Activation of rac1 downstream of nmdars 0 6 0.0 1.0 1.0 |
| Flt3 signaling 0 27 0.0 1.0 1.0 |
| Activation of ampk downstream of nmdars 0 21 0.0 1.0 1.0 |
| Displacement of dna glycosylase by apex1 0 8 0.0 1.0 1.0 |
| N glycan trimming and elongation in the cis golgi 1 4 13.310575635876841 0.09454246530551126 1.0 P33908 |
| Aggrephagy 2 34 2.4984879032258065 0.2024630111897534 1.0 O43237,Q96FJ2 |
| Diseases of programmed cell death 2 53 1.564674256799494 0.3745777826514135 1.0 O75530,Q13546 |
| Alpha protein kinase 1 signaling pathway 0 9 0.0 1.0 1.0 |
| Stat5 activation 0 4 0.0 1.0 1.0 |
| Amino acids regulate mtorc1 1 45 0.9037970062066447 0.6735811793023442 1.0 P55735 |
| Response of mtb to phagocytosis 1 20 2.098287888395688 0.39162847837900855 1.0 P14373 |
| Suppression of phagosomal maturation 0 11 0.0 1.0 1.0 |
| Modulation by mtb of host immune system 0 4 0.0 1.0 1.0 |
| Prevention of phagosomal lysosomal fusion 0 8 0.0 1.0 1.0 |
| Infection with mycobacterium tuberculosis 1 21 1.9931726907630523 0.4065747127007614 1.0 P14373 |
| Suppression of apoptosis 1 6 7.9847389558232935 0.1384198135311803 1.0 P14373 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 0 15 0.0 1.0 1.0 |
| Estrogen stimulated signaling through prkcz 0 6 0.0 1.0 1.0 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0 11 0.0 1.0 1.0 |
| Constitutive signaling by overexpressed erbb2 0 11 0.0 1.0 1.0 |
| Recognition and association of dna glycosylase with site containing an affected purine 0 16 0.0 1.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis 0 4 0.0 1.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 0 6 0.0 1.0 1.0 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 0 20 0.0 1.0 1.0 |
| Ras processing 1 19 2.21508255243195 0.37630734606811034 1.0 O60725 |
| Diseases of base excision repair 0 4 0.0 1.0 1.0 |
| Activation of bad and translocation to mitochondria 0 16 0.0 1.0 1.0 |
| Meiotic recombination 0 31 0.0 1.0 1.0 |
| Interferon alpha beta signaling 0 31 0.0 1.0 1.0 |
| Rhof gtpase cycle 1 42 0.9702223528259379 0.6482306364536417 1.0 Q5JTV8 |
| Activated ntrk3 signals through ras 0 6 0.0 1.0 1.0 |
| Signaling by ntrk3 trkc 1 15 2.849110728628801 0.31108300972667774 1.0 P12931 |
| Blood group systems biosynthesis 0 5 0.0 1.0 1.0 |
| Tysnd1 cleaves peroxisomal proteins 1 7 6.653279785809906 0.15955769838061679 1.0 P09110 |
| Peroxisomal protein import 1 51 0.794859437751004 0.7189520785728546 1.0 P09110 |
| Activated ntrk2 signals through cdk5 0 3 0.0 1.0 1.0 |
| Ntrk2 activates rac1 0 3 0.0 1.0 1.0 |
| Activated ntrk2 signals through fyn 1 4 13.310575635876841 0.09454246530551126 1.0 P12931 |
| Ngf stimulated transcription 0 22 0.0 1.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose 0 3 0.0 1.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake 0 3 0.0 1.0 1.0 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 1 26 1.5937349397590361 0.47599457655385613 1.0 Q8NB78 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0 7 0.0 1.0 1.0 |
| Activated ntrk2 signals through frs2 and frs3 0 7 0.0 1.0 1.0 |
| Activated ntrk2 signals through pi3k 0 4 0.0 1.0 1.0 |
| Erythropoietin activates ras 0 11 0.0 1.0 1.0 |
| Interleukin receptor shc signaling 0 14 0.0 1.0 1.0 |
| Negative regulation of notch4 signaling 3 49 2.613976412603415 0.11821829628593813 1.0 P25787,P49720,P49721 |
| Regulation of signaling by cbl 0 18 0.0 1.0 1.0 |
| Interferon signaling 1 128 0.31050184991936247 0.959148498859686 1.0 P55735 |
| Activated ntrk3 signals through pi3k 1 4 13.310575635876841 0.09454246530551126 1.0 P12931 |
| Activation of noxa and translocation to mitochondria 0 5 0.0 1.0 1.0 |
| Molybdenum cofactor biosynthesis 0 7 0.0 1.0 1.0 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 1 11 3.9903614457831327 0.23906776451302655 1.0 Q6SZW1 |
| Irak2 mediated activation of tak1 complex 0 9 0.0 1.0 1.0 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0 8 0.0 1.0 1.0 |
| Irak1 recruits ikk complex 0 12 0.0 1.0 1.0 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 1 11 3.9903614457831327 0.23906776451302655 1.0 Q6SZW1 |
| Ion transport by p type atpases 2 31 2.757786429365962 0.1757094500446031 1.0 P23634,Q9HD20 |
| Negative regulators of ddx58 ifih1 signaling 1 29 1.4225473321858864 0.5136995062503719 1.0 Q15366 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 1 13 3.324631860776439 0.27596662529306126 1.0 Q13546 |
| Traf6 mediated nf kb activation 0 22 0.0 1.0 1.0 |
| Traf6 mediated irf7 activation 0 15 0.0 1.0 1.0 |
| Release of apoptotic factors from the mitochondria 0 6 0.0 1.0 1.0 |
| Traf3 dependent irf activation pathway 0 13 0.0 1.0 1.0 |
| Transferrin endocytosis and recycling 2 18 5.005040322580645 0.07081534387000758 1.0 Q15904,Q93050 |
| Formation of apoptosome 0 11 0.0 1.0 1.0 |
| Endosomal sorting complex required for transport escrt 1 30 1.3733554909292343 0.5256573230515567 1.0 Q8WUX9 |
| O linked glycosylation of mucins 1 22 1.8980684643335246 0.42115518658714335 1.0 O43505 |
| Regulation of ifna signaling 0 8 0.0 1.0 1.0 |
| Erythropoietin activates stat5 0 4 0.0 1.0 1.0 |
| Response of eif2ak1 hri to heme deficiency 0 10 0.0 1.0 1.0 |
| Signaling by mapk mutants 1 4 13.310575635876841 0.09454246530551126 1.0 Q99956 |
| Sensory perception 2 84 0.970102281667978 0.6144853994637656 1.0 P23634,P47755 |
| Regulation of bach1 activity 0 10 0.0 1.0 1.0 |
| Heme signaling 1 36 1.1372346528973034 0.5914976917658876 1.0 P09601 |
| Mapk3 erk1 activation 0 8 0.0 1.0 1.0 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0 41 0.0 1.0 1.0 |
| Rhobtb gtpase cycle 1 33 1.2442269076305221 0.559801856438838 1.0 P38159 |
| Flt3 signaling by cbl mutants 0 4 0.0 1.0 1.0 |
| Flt3 signaling through src family kinases 0 2 0.0 1.0 1.0 |
| Negative regulation of flt3 0 8 0.0 1.0 1.0 |
| Rhobtb3 atpase cycle 0 9 0.0 1.0 1.0 |
| Inactivation of csf3 g csf signaling 0 17 0.0 1.0 1.0 |
| Signaling by flt3 itd and tkd mutants 0 12 0.0 1.0 1.0 |
| Signaling by flt3 fusion proteins 0 16 0.0 1.0 1.0 |
| Stat5 activation downstream of flt3 itd mutants 0 6 0.0 1.0 1.0 |
| Stat3 nuclear events downstream of alk signaling 0 6 0.0 1.0 1.0 |
| Alk mutants bind tkis 0 12 0.0 1.0 1.0 |
| Signaling by alk in cancer 1 52 0.7791952122214347 0.7258778528724746 1.0 P62753 |
| Rnd1 gtpase cycle 1 36 1.1372346528973034 0.5914976917658876 1.0 P38159 |
| Rnd2 gtpase cycle 2 40 2.102716468590832 0.25702964942480505 1.0 P38159,Q9BTT6 |
| Intrinsic pathway for apoptosis 1 53 0.7641334569045413 0.7326336234518783 1.0 Q96FJ2 |
| Rnd3 gtpase cycle 2 39 2.1597646033129902 0.24788465108468175 1.0 P38159,Q13492 |
| Hemostasis 10 361 1.1390075973409306 0.392351454079403 1.0 P07602,P12931,P23634,P42785,P47755,P62879,P63096,Q9NUQ9,Q9NZJ7,Q9Y624 |
| Signaling by rho gtpases miro gtpases and rhobtb3 16 593 1.1102519664044794 0.38276767422893593 1.0 O15143,O43237,P12931,P30519,P38159,P55735,P61604,Q13492,Q13505,Q15904,Q5JTV8,Q92674,Q96FJ2,Q96HY6,Q9BTT6,Q9UQB8 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 0 20 0.0 1.0 1.0 |
| Factors involved in megakaryocyte development and platelet production 1 117 0.34032682453953744 0.9461410909795847 1.0 P47755 |
| Kinesins 0 47 0.0 1.0 1.0 |
| Antigen presentation folding assembly and peptide loading of class i mhc 2 24 3.6378299120234603 0.11624268982638863 1.0 P55735,Q9NZ08 |
| Class i mhc mediated antigen processing presentation 8 295 1.1125637112333342 0.4368726414992229 1.0 P25787,P49720,P49721,P55735,P55786,P60468,Q8TDB6,Q9NZ08 |
| Antigen processing ubiquitination proteasome degradation 5 250 0.8080799666805498 0.7387037072812201 1.0 P25787,P49720,P49721,P55786,Q8TDB6 |
| Growth hormone receptor signaling 0 15 0.0 1.0 1.0 |
| Apoptosis 5 159 1.2976411343758283 0.3509014680054083 1.0 P25787,P49720,P49721,Q13546,Q96FJ2 |
| Gaba receptor activation 2 18 5.005040322580645 0.07081534387000758 1.0 P62879,P63096 |
| Serine biosynthesis 0 7 0.0 1.0 1.0 |
| Amyloid fiber formation 0 41 0.0 1.0 1.0 |
| Termination of o glycan biosynthesis 0 4 0.0 1.0 1.0 |
| Reactions specific to the complex n glycan synthesis pathway 0 6 0.0 1.0 1.0 |
| N glycan antennae elongation 0 8 0.0 1.0 1.0 |
| N glycan antennae elongation in the medial trans golgi 0 15 0.0 1.0 1.0 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0 10 0.0 1.0 1.0 |
| Defective intrinsic pathway for apoptosis 0 24 0.0 1.0 1.0 |
| Nuclear events stimulated by alk signaling in cancer 1 17 2.4924698795180724 0.34450269493005076 1.0 P62753 |
| Sensory perception of taste 0 4 0.0 1.0 1.0 |
| Miro gtpase cycle 0 8 0.0 1.0 1.0 |
| Defects of contact activation system cas and kallikrein kinin system kks 0 5 0.0 1.0 1.0 |
| Translation of sars cov 2 structural proteins 1 41 0.994578313253012 0.6393520558322405 1.0 P04844 |
| Attachment and entry 0 4 0.0 1.0 1.0 |
| Signaling by kit in disease 1 18 2.3456177651783605 0.3606019508791212 1.0 P12931 |
| Sealing of the nuclear envelope ne by escrt iii 1 26 1.5937349397590361 0.47599457655385613 1.0 Q8WUX9 |
| Defective factor ix causes hemophilia b 0 3 0.0 1.0 1.0 |
| Signaling by erbb2 ecd mutants 0 15 0.0 1.0 1.0 |
| Pexophagy 0 9 0.0 1.0 1.0 |
| Killing mechanisms 0 9 0.0 1.0 1.0 |
| Parasite infection 3 50 2.55810147299509 0.12361304926291004 1.0 O15143,P12931,Q9UQB8 |
| Fcgr3a mediated il10 synthesis 1 23 1.8116100766703176 0.4353788157626653 1.0 P12931 |
| Recognition of dna damage by pcna containing replication complex 1 30 1.3733554909292343 0.5256573230515567 1.0 O94782 |
| Anti inflammatory response favouring leishmania parasite infection 3 46 2.7971942378307126 0.10259295039812891 1.0 P12931,P62879,P63096 |
| Cd163 mediating an anti inflammatory response 0 5 0.0 1.0 1.0 |
| Sensory processing of sound by outer hair cells of the cochlea 1 25 1.6603078982597055 0.4627901258069825 1.0 P23634 |
| Defective factor viii causes hemophilia a 0 3 0.0 1.0 1.0 |
| Purinergic signaling in leishmaniasis infection 1 12 3.6272362175976633 0.25774553170225967 1.0 P09601 |
| Adora2b mediated anti inflammatory cytokines production 2 30 2.8565668202764978 0.16692281896733152 1.0 P62879,P63096 |
| Signaling by mras complex mutants 0 8 0.0 1.0 1.0 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0 17 0.0 1.0 1.0 |
| Sensory processing of sound 2 40 2.102716468590832 0.25702964942480505 1.0 P23634,P47755 |
| Translesion synthesis by polh 0 20 0.0 1.0 1.0 |
| Inhibition of dna recombination at telomere 1 28 1.475383013535624 0.5014414780701414 1.0 P62875 |
| Maturation of sars cov 2 nucleoprotein 0 13 0.0 1.0 1.0 |
| Signaling by pdgfr in disease 0 17 0.0 1.0 1.0 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0 11 0.0 1.0 1.0 |
| Maturation of sars cov 2 spike protein 1 24 1.7326698096734765 0.4492542995146525 1.0 P04844 |
| Sars cov 2 infection 2 62 1.3287634408602151 0.45156828371782387 1.0 P04844,Q8WUX9 |
| Defective ripk1 mediated regulated necrosis 1 6 7.9847389558232935 0.1384198135311803 1.0 Q13546 |
| Transcriptional regulation of testis differentiation 0 4 0.0 1.0 1.0 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 0 20 0.0 1.0 1.0 |
| Translation of sars cov 1 structural proteins 0 22 0.0 1.0 1.0 |
| Maturation of sars cov 1 spike protein 0 5 0.0 1.0 1.0 |
| Maturation of protein 3a 0 5 0.0 1.0 1.0 |
| Maturation of sars cov 1 nucleoprotein 0 9 0.0 1.0 1.0 |
| Flt3 signaling in disease 0 22 0.0 1.0 1.0 |
| Sars cov infections 4 128 1.2879622344610542 0.384298354139203 1.0 P04844,P21964,Q13546,Q8WUX9 |
| Translation of replicase and assembly of the replication transcription complex 1 13 3.324631860776439 0.27596662529306126 1.0 Q8WUX9 |
| Potential therapeutics for sars 2 68 1.2072336265884653 0.49983079895380533 1.0 P21964,Q13546 |
| Sars cov 1 infection 1 42 0.9702223528259379 0.6482306364536417 1.0 Q8WUX9 |
| Diseases of dna repair 1 33 1.2442269076305221 0.559801856438838 1.0 Q9UQ84 |
| Diseases of mitotic cell cycle 0 38 0.0 1.0 1.0 |
| Nervous system development 15 443 1.419467090872937 0.12845569308153484 1.0 O14786,O15143,P12931,P18433,P25787,P42766,P49720,P49721,P62081,P62269,P62753,P62841,P62847,P62899,Q92796 |
| Signaling by csf3 g csf 0 22 0.0 1.0 1.0 |
| Signaling by membrane tethered fusions of pdgfra or pdgfrb 0 3 0.0 1.0 1.0 |
| Defective f9 activation 0 1 0.0 1.0 1.0 |
| Erythropoietin activates phospholipase c gamma plcg 0 5 0.0 1.0 1.0 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 8 0.0 1.0 1.0 |
| Activated ntrk2 signals through ras 0 6 0.0 1.0 1.0 |
| Runx2 regulates genes involved in cell migration 0 5 0.0 1.0 1.0 |
| Runx2 regulates bone development 1 26 1.5937349397590361 0.47599457655385613 1.0 P12931 |
| Runx2 regulates chondrocyte maturation 0 3 0.0 1.0 1.0 |
| Runx2 regulates osteoblast differentiation 1 20 2.098287888395688 0.39162847837900855 1.0 P12931 |
| Runx1 regulates transcription of genes involved in wnt signaling 0 3 0.0 1.0 1.0 |
| Runx1 regulates transcription of genes involved in interleukin signaling 0 4 0.0 1.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0 5 0.0 1.0 1.0 |
| Runx1 regulates transcription of genes involved in bcr signaling 0 4 0.0 1.0 1.0 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0 36 0.0 1.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of keratinocytes 0 4 0.0 1.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 3 68 1.8463407038305824 0.23275165888233573 1.0 P25787,P49720,P49721 |
| Esr mediated signaling 4 136 1.2089184528208918 0.42867484277074774 1.0 P12931,P62875,P62879,P63096 |
| Aryl hydrocarbon receptor signalling 1 7 6.653279785809906 0.15955769838061679 1.0 O00170 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0 39 0.0 1.0 1.0 |
| Runx1 regulates expression of components of tight junctions 0 4 0.0 1.0 1.0 |
| Digestion 0 1 0.0 1.0 1.0 |
| Receptor mediated mitophagy 1 10 4.4341811691209285 0.2199219252501269 1.0 P12931 |
| Regulation of runx1 expression and activity 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Runx1 regulates estrogen receptor mediated transcription 0 5 0.0 1.0 1.0 |
| Runx3 regulates cdkn1a transcription 0 7 0.0 1.0 1.0 |
| Gaba synthesis release reuptake and degradation 0 12 0.0 1.0 1.0 |
| Runx3 regulates notch signaling 0 11 0.0 1.0 1.0 |
| Regulation of pten mrna translation 0 9 0.0 1.0 1.0 |
| Carboxyterminal post translational modifications of tubulin 0 25 0.0 1.0 1.0 |
| Opioid signalling 2 63 1.3068482284505554 0.45979630753353173 1.0 P62879,P63096 |
| Pka mediated phosphorylation of creb 0 13 0.0 1.0 1.0 |
| Transcriptional regulation by e2f6 1 34 1.2064013630278692 0.5706303062959026 1.0 O75530 |
| Runx3 regulates bcl2l11 bim transcription 0 5 0.0 1.0 1.0 |
| Runx3 regulates p14 arf 0 11 0.0 1.0 1.0 |
| Runx3 regulates yap1 mediated transcription 0 6 0.0 1.0 1.0 |
| Neddylation 3 185 0.651599412733016 0.836426281354077 1.0 P25787,P49720,P49721 |
| Runx3 regulates wnt signaling 0 8 0.0 1.0 1.0 |
| Camk iv mediated phosphorylation of creb 0 8 0.0 1.0 1.0 |
| Processing of smdt1 0 16 0.0 1.0 1.0 |
| Ca dependent events 0 26 0.0 1.0 1.0 |
| Runx3 regulates immune response and cell migration 0 4 0.0 1.0 1.0 |
| Mitochondrial calcium ion transport 2 21 4.213497453310696 0.09270379205394921 1.0 P21796,P45880 |
| Regulation of pten stability and activity 4 63 2.7248174176657023 0.0684092062727696 1.0 P14373,P25787,P49720,P49721 |
| Regulation of pten localization 0 8 0.0 1.0 1.0 |
| Competing endogenous rnas cernas regulate pten translation 0 8 0.0 1.0 1.0 |
| Collagen chain trimerization 0 13 0.0 1.0 1.0 |
| Regulation of pten gene transcription 1 56 0.7222343921139102 0.7519219756551887 1.0 O75530 |
| G protein mediated events 1 40 1.020183297291731 0.6302503007248048 1.0 P63096 |
| Nucleotide catabolism 0 22 0.0 1.0 1.0 |
| Transcriptional regulation by runx1 4 149 1.0990748528174936 0.49877144788080474 1.0 P12931,P25787,P49720,P49721 |
| Transcriptional regulation by runx3 4 86 1.9559785841760857 0.16013600828187272 1.0 P12931,P25787,P49720,P49721 |
| Reelin signalling pathway 0 3 0.0 1.0 1.0 |
| Met activates ptpn11 0 5 0.0 1.0 1.0 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0 27 0.0 1.0 1.0 |
| Downregulation of erbb2 signaling 0 18 0.0 1.0 1.0 |
| Ptk6 promotes hif1a stabilization 0 2 0.0 1.0 1.0 |
| Clathrin mediated endocytosis 3 119 1.029247521987994 0.5619917467058034 1.0 P42566,Q13492,Q9NVZ3 |
| Cargo recognition for clathrin mediated endocytosis 3 78 1.5985425101214574 0.29923050214098046 1.0 P42566,Q13492,Q9NVZ3 |
| Golgi to er retrograde transport 5 115 1.824860853432282 0.15201062068023052 1.0 O43237,P24390,P47755,Q13561,Q96FJ2 |
| Interleukin 20 family signaling 0 11 0.0 1.0 1.0 |
| Aurka activation by tpx2 2 73 1.1216492503407542 0.5379206292852479 1.0 O94927,Q13561 |
| Tbc rabgaps 0 39 0.0 1.0 1.0 |
| Transcriptional regulation by ventx 0 37 0.0 1.0 1.0 |
| Ret signaling 1 26 1.5937349397590361 0.47599457655385613 1.0 P12931 |
| Signaling by fgfr3 fusions in cancer 0 10 0.0 1.0 1.0 |
| Signaling by mst1 0 3 0.0 1.0 1.0 |
| The role of gtse1 in g2 m progression after g2 checkpoint 4 67 2.550780745902697 0.08175488251216179 1.0 P14635,P25787,P49720,P49721 |
| Protein ubiquitination 0 58 0.0 1.0 1.0 |
| Met activates pi3k akt signaling 0 6 0.0 1.0 1.0 |
| Met activates ras signaling 0 11 0.0 1.0 1.0 |
| Vldl assembly 0 3 0.0 1.0 1.0 |
| Electric transmission across gap junctions 0 2 0.0 1.0 1.0 |
| Vldlr internalisation and degradation 0 9 0.0 1.0 1.0 |
| E3 ubiquitin ligases ubiquitinate target proteins 0 40 0.0 1.0 1.0 |
| Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 0 3 0.0 1.0 1.0 |
| Protein methylation 0 16 0.0 1.0 1.0 |
| Inla mediated entry of listeria monocytogenes into host cells 1 9 4.988955823293173 0.20029633215213802 1.0 P12931 |
| Listeria monocytogenes entry into host cells 2 21 4.213497453310696 0.09270379205394921 1.0 P12931,P42566 |
| Rab gefs exchange gtp for gdp on rabs 0 79 0.0 1.0 1.0 |
| Met promotes cell motility 1 29 1.4225473321858864 0.5136995062503719 1.0 P12931 |
| Met receptor recycling 0 10 0.0 1.0 1.0 |
| Met activates rap1 and rac1 0 11 0.0 1.0 1.0 |
| Met interacts with tns proteins 0 4 0.0 1.0 1.0 |
| Inlb mediated entry of listeria monocytogenes into host cell 1 15 2.849110728628801 0.31108300972667774 1.0 P42566 |
| Creb3 factors activate genes 0 3 0.0 1.0 1.0 |
| Met activates ptk2 signaling 1 19 2.21508255243195 0.37630734606811034 1.0 P12931 |
| Rab geranylgeranylation 0 54 0.0 1.0 1.0 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0 5 0.0 1.0 1.0 |
| Rrna processing in the mitochondrion 0 10 0.0 1.0 1.0 |
| Tfap2 ap 2 family regulates transcription of cell cycle factors 0 5 0.0 1.0 1.0 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0 7 0.0 1.0 1.0 |
| Activation of the tfap2 ap 2 family of transcription factors 0 8 0.0 1.0 1.0 |
| Negative regulation of activity of tfap2 ap 2 family transcription factors 0 7 0.0 1.0 1.0 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 0 26 0.0 1.0 1.0 |
| Nucleotide biosynthesis 0 16 0.0 1.0 1.0 |
| Nucleotide salvage 0 20 0.0 1.0 1.0 |
| Apoptotic factor mediated response 0 20 0.0 1.0 1.0 |
| Signaling by notch4 3 71 1.7643486544415337 0.25246138092126835 1.0 P25787,P49720,P49721 |
| Notch3 intracellular domain regulates transcription 0 18 0.0 1.0 1.0 |
| Notch3 activation and transmission of signal to the nucleus 0 18 0.0 1.0 1.0 |
| Rhot1 gtpase cycle 0 5 0.0 1.0 1.0 |
| Rhov gtpase cycle 0 35 0.0 1.0 1.0 |
| Rac3 gtpase cycle 1 83 0.4831031442844549 0.8736769220313676 1.0 Q9UQB8 |
| Rhobtb1 gtpase cycle 1 22 1.8980684643335246 0.42115518658714335 1.0 P38159 |
| Rhou gtpase cycle 1 39 1.04713591206933 0.6209197844592236 1.0 P12931 |
| Rhobtb2 gtpase cycle 1 22 1.8980684643335246 0.42115518658714335 1.0 P38159 |
| Rhoj gtpase cycle 0 55 0.0 1.0 1.0 |
| Rhog gtpase cycle 1 71 0.5666092943201377 0.8294508517100334 1.0 P61604 |
| Rhoh gtpase cycle 0 32 0.0 1.0 1.0 |
| Rhoq gtpase cycle 0 59 0.0 1.0 1.0 |
| Rhod gtpase cycle 1 50 0.8111630194246373 0.7118520401392299 1.0 Q5JTV8 |
| Rac2 gtpase cycle 1 81 0.49528112449799194 0.8671928728330457 1.0 Q13505 |
| Rac1 gtpase cycle 1 152 0.2605122476661613 0.9776735288213427 1.0 Q9UQB8 |
| Cdc42 gtpase cycle 1 134 0.296313071836217 0.9648706217538829 1.0 Q9UQB8 |
| Rhoc gtpase cycle 0 75 0.0 1.0 1.0 |
| Rhob gtpase cycle 0 69 0.0 1.0 1.0 |
| Notch4 intracellular domain regulates transcription 0 15 0.0 1.0 1.0 |
| Rho gtpase cycle 11 387 1.1714368378883646 0.3511994758769184 1.0 P12931,P30519,P38159,P61604,Q13492,Q13505,Q15904,Q5JTV8,Q96HY6,Q9BTT6,Q9UQB8 |
| Notch4 activation and transmission of signal to the nucleus 0 8 0.0 1.0 1.0 |
| Ticam1 dependent activation of irf3 irf7 0 10 0.0 1.0 1.0 |
| Nr1h2 and nr1h3 mediated signaling 1 31 1.3274431057563587 0.5373222521600443 1.0 Q8NB78 |
| Mecp2 regulates transcription factors 0 4 0.0 1.0 1.0 |
| Mecp2 regulates transcription of neuronal ligands 0 4 0.0 1.0 1.0 |
| Mecp2 regulates neuronal receptors and channels 0 12 0.0 1.0 1.0 |
| Regulation of mecp2 expression and activity 0 30 0.0 1.0 1.0 |
| Loss of mecp2 binding ability to the ncor smrt complex 0 7 0.0 1.0 1.0 |
| Interleukin 21 signaling 0 5 0.0 1.0 1.0 |
| Interleukin 27 signaling 0 8 0.0 1.0 1.0 |
| Interleukin 23 signaling 0 5 0.0 1.0 1.0 |
| Interleukin 1 signaling 3 82 1.5169886742171885 0.3261957373675167 1.0 P25787,P49720,P49721 |
| Activation of caspases through apoptosome mediated cleavage 0 6 0.0 1.0 1.0 |
| Interleukin 2 signaling 0 5 0.0 1.0 1.0 |
| Biosynthesis of maresins 0 1 0.0 1.0 1.0 |
| Biosynthesis of epa derived spms 0 3 0.0 1.0 1.0 |
| Biosynthesis of specialized proresolving mediators spms 0 6 0.0 1.0 1.0 |
| Estrogen dependent gene expression 1 90 0.44479039754523714 0.8939860511714703 1.0 P62875 |
| Noncanonical activation of notch3 0 8 0.0 1.0 1.0 |
| Interleukin 36 pathway 0 1 0.0 1.0 1.0 |
| Ticam1 traf6 dependent induction of tak1 complex 0 10 0.0 1.0 1.0 |
| Tlr3 mediated ticam1 dependent programmed cell death 1 5 9.981927710843374 0.1167524715539159 1.0 Q13546 |
| Signaling by notch3 0 35 0.0 1.0 1.0 |
| Robo receptors bind akap5 0 8 0.0 1.0 1.0 |
| Cytochrome c mediated apoptotic response 0 13 0.0 1.0 1.0 |
| Glutamate and glutamine metabolism 0 14 0.0 1.0 1.0 |
| Phenylalanine metabolism 0 4 0.0 1.0 1.0 |
| Hdl remodeling 0 3 0.0 1.0 1.0 |
| Vldl clearance 0 4 0.0 1.0 1.0 |
| Plasma lipoprotein clearance 2 23 3.8114439324116742 0.10823534446329469 1.0 P61916,Q8WTV0 |
| Ldl remodeling 0 2 0.0 1.0 1.0 |
| Ldl clearance 1 17 2.4924698795180724 0.34450269493005076 1.0 P61916 |
| Chylomicron clearance 0 4 0.0 1.0 1.0 |
| Smac xiap regulated apoptotic response 0 8 0.0 1.0 1.0 |
| Chylomicron remodeling 0 4 0.0 1.0 1.0 |
| Plasma lipoprotein remodeling 0 12 0.0 1.0 1.0 |
| Plasma lipoprotein assembly 0 12 0.0 1.0 1.0 |
| Hdl assembly 0 6 0.0 1.0 1.0 |
| Assembly of active lpl and lipc lipase complexes 0 7 0.0 1.0 1.0 |
| Chylomicron assembly 0 5 0.0 1.0 1.0 |
| Digestion and absorption 0 1 0.0 1.0 1.0 |
| Aspartate and asparagine metabolism 0 7 0.0 1.0 1.0 |
| Phenylalanine and tyrosine metabolism 0 6 0.0 1.0 1.0 |
| Tyrosine catabolism 0 2 0.0 1.0 1.0 |
| Lipid particle organization 0 1 0.0 1.0 1.0 |
| G beta gamma signalling through cdc42 1 14 3.068582020389249 0.2937421672442234 1.0 P62879 |
| Apoptotic cleavage of cellular proteins 0 35 0.0 1.0 1.0 |
| Metabolism of cofactors 1 15 2.849110728628801 0.31108300972667774 1.0 Q86YH6 |
| Calnexin calreticulin cycle 0 23 0.0 1.0 1.0 |
| Er quality control compartment erqc 0 18 0.0 1.0 1.0 |
| Extra nuclear estrogen signaling 3 47 2.733345601766654 0.10770516157514859 1.0 P12931,P62879,P63096 |
| Interleukin 37 signaling 0 12 0.0 1.0 1.0 |
| Rab regulation of trafficking 0 107 0.0 1.0 1.0 |
| Signaling by tgfb family members 1 79 0.5080836165173515 0.8603774023730821 1.0 Q9Y624 |
| Signaling by receptor tyrosine kinases 8 344 0.9454939000393546 0.6114494940386941 1.0 O14786,P12931,P16949,P42566,P62875,Q15904,Q93050,Q9UQB8 |
| Signaling by nuclear receptors 6 178 1.397350362180709 0.27177010799279194 1.0 P12931,P62875,P62879,P63096,Q8NB78,Q8NBN7 |
| Intracellular signaling by second messengers 6 233 1.0528273272188922 0.5100322368593952 1.0 O75530,P12931,P14373,P25787,P49720,P49721 |
| Butyrophilin btn family interactions 0 5 0.0 1.0 1.0 |
| Signaling by erythropoietin 0 19 0.0 1.0 1.0 |
| Loss of function of mecp2 in rett syndrome 0 12 0.0 1.0 1.0 |
| Transcriptional regulation by mecp2 0 45 0.0 1.0 1.0 |
| Interleukin 9 signaling 0 4 0.0 1.0 1.0 |
| Interleukin 35 signalling 0 9 0.0 1.0 1.0 |
| Oas antiviral response 0 6 0.0 1.0 1.0 |
| Interleukin 15 signaling 0 8 0.0 1.0 1.0 |
| Glycogen metabolism 0 20 0.0 1.0 1.0 |
| Rhoa gtpase cycle 3 134 0.9100040176777823 0.6426014828581943 1.0 P30519,Q15904,Q96HY6 |
| Triglyceride metabolism 0 20 0.0 1.0 1.0 |
| Signaling by ntrk2 trkb 1 18 2.3456177651783605 0.3606019508791212 1.0 P12931 |
| Activation of ras in b cells 0 3 0.0 1.0 1.0 |
| Uptake and actions of bacterial toxins 0 23 0.0 1.0 1.0 |
| Signaling by rnf43 mutants 0 4 0.0 1.0 1.0 |
| Biotin transport and metabolism 0 11 0.0 1.0 1.0 |
| Metabolism of folate and pterines 1 15 2.849110728628801 0.31108300972667774 1.0 Q9H2D1 |
| Cobalamin cbl vitamin b12 transport and metabolism 1 13 3.324631860776439 0.27596662529306126 1.0 Q96EY8 |
| Pi3k events in erbb2 signaling 0 7 0.0 1.0 1.0 |
| Grb2 events in erbb2 signaling 0 7 0.0 1.0 1.0 |
| Beta catenin phosphorylation cascade 0 16 0.0 1.0 1.0 |
| Pregnenolone biosynthesis 1 8 5.70223752151463 0.1801790130745941 1.0 P30536 |
| Interleukin 7 signaling 0 13 0.0 1.0 1.0 |
| Coenzyme a biosynthesis 0 8 0.0 1.0 1.0 |
| Signaling by wnt 4 213 0.7575368576652274 0.7713580108650213 1.0 P25787,P49720,P49721,P62879 |
| Degradation of beta catenin by the destruction complex 3 77 1.6203085676769888 0.29250483836522556 1.0 P25787,P49720,P49721 |
| Vegf ligand receptor interactions 0 2 0.0 1.0 1.0 |
| Signaling by vegf 3 87 1.4259687680740312 0.3598837636022959 1.0 O14786,P12931,Q9UQB8 |
| Bile acid and bile salt metabolism 0 22 0.0 1.0 1.0 |
| Synthesis of bile acids and bile salts via 27 hydroxycholesterol 0 7 0.0 1.0 1.0 |
| Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0 5 0.0 1.0 1.0 |
| P75 ntr receptor mediated signalling 1 81 0.49528112449799194 0.8671928728330457 1.0 P42575 |
| P75ntr regulates axonogenesis 0 5 0.0 1.0 1.0 |
| Rho gtpase effectors 7 246 1.169981231812938 0.39886361775197404 1.0 O15143,O43237,P12931,P55735,Q92674,Q96FJ2,Q9UQB8 |
| Vitamin d calciferol metabolism 0 8 0.0 1.0 1.0 |
| Nicotinate metabolism 1 18 2.3456177651783605 0.3606019508791212 1.0 P43490 |
| Vitamin b1 thiamin metabolism 0 5 0.0 1.0 1.0 |
| Membrane trafficking 13 532 0.9963252928790355 0.546227554247808 1.0 O43237,P12931,P24390,P33908,P42566,P47755,P55735,Q12907,Q13492,Q13561,Q8WUX9,Q96FJ2,Q9NVZ3 |
| Nuclear signaling by erbb4 2 18 5.005040322580645 0.07081534387000758 1.0 P12931,P16949 |
| Creb phosphorylation 0 7 0.0 1.0 1.0 |
| Negative regulation of the pi3k akt network 1 62 0.6507999209954572 0.7864389397029559 1.0 P12931 |
| Vitamin b5 pantothenate metabolism 0 13 0.0 1.0 1.0 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0 26 0.0 1.0 1.0 |
| Erk mapk targets 0 20 0.0 1.0 1.0 |
| Nuclear events kinase and transcription factor activation 0 42 0.0 1.0 1.0 |
| Akt phosphorylates targets in the nucleus 0 9 0.0 1.0 1.0 |
| Akt phosphorylates targets in the cytosol 0 14 0.0 1.0 1.0 |
| Pi3k akt activation 0 7 0.0 1.0 1.0 |
| Signaling by notch2 0 22 0.0 1.0 1.0 |
| Signaling by notch1 0 56 0.0 1.0 1.0 |
| Nicotinamide salvaging 1 11 3.9903614457831327 0.23906776451302655 1.0 P43490 |
| A tetrasaccharide linker sequence is required for gag synthesis 0 16 0.0 1.0 1.0 |
| Metabolism of vitamins and cofactors 6 134 1.8861424180327868 0.11147427307267328 1.0 P00387,P43490,P78417,Q86YH6,Q96EY8,Q9H2D1 |
| Metabolism of water soluble vitamins and cofactors 5 91 2.3398196487897485 0.07259957313154455 1.0 P00387,P43490,P78417,Q96EY8,Q9H2D1 |
| Vitamin b2 riboflavin metabolism 0 4 0.0 1.0 1.0 |
| Downregulation of erbb4 signaling 1 7 6.653279785809906 0.15955769838061679 1.0 P12931 |
| Regulated proteolysis of p75ntr 0 11 0.0 1.0 1.0 |
| P75ntr negatively regulates cell cycle via sc1 0 5 0.0 1.0 1.0 |
| Nrage signals death through jnk 0 47 0.0 1.0 1.0 |
| P75ntr signals via nf kb 0 14 0.0 1.0 1.0 |
| Cellular hexose transport 0 6 0.0 1.0 1.0 |
| Signalling to p38 via rit and rin 0 3 0.0 1.0 1.0 |
| Signalling to erks 1 30 1.3733554909292343 0.5256573230515567 1.0 P12931 |
| Scf skp2 mediated degradation of p27 p21 3 54 2.356513455584663 0.14604051425702808 1.0 P25787,P49720,P49721 |
| Ngf independant trka activation 0 1 0.0 1.0 1.0 |
| Activation of trka receptors 0 1 0.0 1.0 1.0 |
| Signaling by pdgf 1 35 1.1708008504606662 0.5811934260914344 1.0 P12931 |
| Downstream signal transduction 1 23 1.8116100766703176 0.4353788157626653 1.0 P12931 |
| Regulation of beta cell development 0 22 0.0 1.0 1.0 |
| Synthesis of ip3 and ip4 in the cytosol 0 20 0.0 1.0 1.0 |
| Synthesis of ip2 ip and ins in the cytosol 0 12 0.0 1.0 1.0 |
| Synthesis of pyrophosphates in the cytosol 1 10 4.4341811691209285 0.2199219252501269 1.0 Q92551 |
| Organelle biogenesis and maintenance 9 268 1.3967381726717827 0.21242688664262138 1.0 O75964,O94927,P11474,P48735,Q13505,Q13561,Q96FJ2,Q9BUR5,Q9Y547 |
| Fgfr2 mutant receptor activation 1 18 2.3456177651783605 0.3606019508791212 1.0 P62875 |
| Fgfr1 mutant receptor activation 0 22 0.0 1.0 1.0 |
| Signaling by cytosolic fgfr1 fusion mutants 0 18 0.0 1.0 1.0 |
| Cytosolic sensors of pathogen associated dna 2 56 1.477299880525687 0.4007853524207055 1.0 P62875,Q13546 |
| Sting mediated induction of host immune responses 0 10 0.0 1.0 1.0 |
| Egfr downregulation 1 22 1.8980684643335246 0.42115518658714335 1.0 P42566 |
| Heme biosynthesis 0 12 0.0 1.0 1.0 |
| Trans golgi network vesicle budding 1 69 0.583392393101819 0.8207074876125077 1.0 Q13492 |
| Adaptive immune system 13 504 1.056270248438131 0.46634795898456666 1.0 O43237,P12931,P25787,P47755,P49720,P49721,P55735,P55786,P60468,Q13561,Q8TDB6,Q96FJ2,Q9NZ08 |
| Fgfr3 ligand binding and activation 0 3 0.0 1.0 1.0 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0 13 0.0 1.0 1.0 |
| Estrogen biosynthesis 0 2 0.0 1.0 1.0 |
| Developmental biology 18 665 1.1151068592442572 0.3661897766326146 1.0 O14786,O15143,O75530,P12931,P18433,P25787,P42766,P49720,P49721,P62081,P62269,P62753,P62841,P62847,P62875,P62899,Q71SY5,Q92796 |
| Synthesis of bile acids and bile salts 0 20 0.0 1.0 1.0 |
| Snrnp assembly 3 53 2.4038866396761134 0.14031264739793226 1.0 P55735,P62314,Q9NWZ8 |
| Cytokine signaling in immune system 9 392 0.9324398990282006 0.6280416394525572 1.0 O00170,P09601,P25787,P49720,P49721,P55735,P78417,Q13126,Q53EL6 |
| Pre notch expression and processing 1 50 0.8111630194246373 0.7118520401392299 1.0 Q9H488 |
| Pre notch processing in golgi 0 13 0.0 1.0 1.0 |
| Pre notch processing in the endoplasmic reticulum 1 5 9.981927710843374 0.1167524715539159 1.0 Q9H488 |
| Gap junction degradation 0 12 0.0 1.0 1.0 |
| Transport of connexons to the plasma membrane 0 14 0.0 1.0 1.0 |
| Gap junction assembly 0 15 0.0 1.0 1.0 |
| Fgfr2b ligand binding and activation 0 2 0.0 1.0 1.0 |
| Fgfr2c ligand binding and activation 0 2 0.0 1.0 1.0 |
| Fgfr1c ligand binding and activation 0 2 0.0 1.0 1.0 |
| Fgfr3b ligand binding and activation 0 1 0.0 1.0 1.0 |
| Fgfr1b ligand binding and activation 0 2 0.0 1.0 1.0 |
| Fgfr1 ligand binding and activation 0 2 0.0 1.0 1.0 |
| Fgfr2 ligand binding and activation 0 2 0.0 1.0 1.0 |
| Signaling by fgfr 2 57 1.4502932551319647 0.4094079381471642 1.0 P12931,P62875 |
| Shc1 events in erbb4 signaling 0 6 0.0 1.0 1.0 |
| Signaling by bmp 0 15 0.0 1.0 1.0 |
| Signaling by alk 1 19 2.21508255243195 0.37630734606811034 1.0 P12931 |
| Synthesis of 12 eicosatetraenoic acid derivatives 0 2 0.0 1.0 1.0 |
| Synthesis of lipoxins lx 0 1 0.0 1.0 1.0 |
| Synthesis of leukotrienes lt and eoxins ex 0 4 0.0 1.0 1.0 |
| Synthesis of 5 eicosatetraenoic acids 0 3 0.0 1.0 1.0 |
| Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet 0 1 0.0 1.0 1.0 |
| Mhc class ii antigen presentation 5 100 2.116219119226638 0.09898866976632938 1.0 O43237,P47755,P55735,Q13561,Q96FJ2 |
| Molecules associated with elastic fibres 0 18 0.0 1.0 1.0 |
| Egfr interacts with phospholipase c gamma 0 2 0.0 1.0 1.0 |
| Dopamine neurotransmitter release cycle 0 18 0.0 1.0 1.0 |
| Prc2 methylates histones and dna 1 23 1.8116100766703176 0.4353788157626653 1.0 O75530 |
| Activated notch1 transmits signal to the nucleus 0 21 0.0 1.0 1.0 |
| Notch1 intracellular domain regulates transcription 0 39 0.0 1.0 1.0 |
| Epigenetic regulation of gene expression 2 102 0.7940322580645162 0.7182524879345031 1.0 O75530,P62875 |
| Cyp2e1 reactions 0 1 0.0 1.0 1.0 |
| Xenobiotics 0 4 0.0 1.0 1.0 |
| Eicosanoids 0 1 0.0 1.0 1.0 |
| Endogenous sterols 0 12 0.0 1.0 1.0 |
| Miscellaneous substrates 0 2 0.0 1.0 1.0 |
| Shc1 events in erbb2 signaling 0 13 0.0 1.0 1.0 |
| Arachidonic acid metabolism 1 18 2.3456177651783605 0.3606019508791212 1.0 Q8N8N7 |
| Cytochrome p450 arranged by substrate type 0 15 0.0 1.0 1.0 |
| Synthesis of 15 eicosatetraenoic acid derivatives 0 3 0.0 1.0 1.0 |
| Synthesis of 16 20 hydroxyeicosatetraenoic acids hete 0 1 0.0 1.0 1.0 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 0 29 0.0 1.0 1.0 |
| Downregulation of smad2 3 smad4 transcriptional activity 0 23 0.0 1.0 1.0 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 0 41 0.0 1.0 1.0 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 1 14 3.068582020389249 0.2937421672442234 1.0 Q9Y624 |
| Tgf beta receptor signaling activates smads 0 28 0.0 1.0 1.0 |
| Downregulation of tgf beta receptor signaling 0 22 0.0 1.0 1.0 |
| Binding and uptake of ligands by scavenger receptors 1 17 2.4924698795180724 0.34450269493005076 1.0 Q8WTV0 |
| Dap12 interactions 0 21 0.0 1.0 1.0 |
| Scavenging of heme from plasma 0 2 0.0 1.0 1.0 |
| Synthesis of prostaglandins pg and thromboxanes tx 1 8 5.70223752151463 0.1801790130745941 1.0 Q8N8N7 |
| Abacavir metabolism 0 4 0.0 1.0 1.0 |
| Abacavir transport and metabolism 0 6 0.0 1.0 1.0 |
| Abacavir transmembrane transport 0 2 0.0 1.0 1.0 |
| Hyaluronan uptake and degradation 0 8 0.0 1.0 1.0 |
| Integrin cell surface interactions 1 37 1.105533244087461 0.6015494217836266 1.0 Q9Y624 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 0 8 0.0 1.0 1.0 |
| Transcriptional activation of mitochondrial biogenesis 2 51 1.6288676761026992 0.35685011838570857 1.0 P11474,P48735 |
| Hyaluronan biosynthesis and export 0 1 0.0 1.0 1.0 |
| Hyaluronan metabolism 0 9 0.0 1.0 1.0 |
| Ubiquinol biosynthesis 1 7 6.653279785809906 0.15955769838061679 1.0 Q86YH6 |
| Nef mediated cd8 down regulation 0 6 0.0 1.0 1.0 |
| Pi3k events in erbb4 signaling 0 2 0.0 1.0 1.0 |
| Tie2 signaling 0 12 0.0 1.0 1.0 |
| Signaling by hippo 0 21 0.0 1.0 1.0 |
| Cell surface interactions at the vascular wall 2 70 1.1714895635673623 0.5153064963506486 1.0 P12931,Q9Y624 |
| Erks are inactivated 0 11 0.0 1.0 1.0 |
| Calcineurin activates nfat 0 8 0.0 1.0 1.0 |
| Generation of second messenger molecules 0 11 0.0 1.0 1.0 |
| Cs ds degradation 0 7 0.0 1.0 1.0 |
| Tcr signaling 3 85 1.461044731904809 0.3464251796166452 1.0 P25787,P49720,P49721 |
| Hs gag biosynthesis 0 17 0.0 1.0 1.0 |
| Dermatan sulfate biosynthesis 0 6 0.0 1.0 1.0 |
| Chondroitin sulfate biosynthesis 0 12 0.0 1.0 1.0 |
| Keratan sulfate degradation 1 6 7.9847389558232935 0.1384198135311803 1.0 P16278 |
| Keratan sulfate biosynthesis 1 11 3.9903614457831327 0.23906776451302655 1.0 O43505 |
| Metabolism of angiotensinogen to angiotensins 0 8 0.0 1.0 1.0 |
| Assembly of collagen fibrils and other multimeric structures 0 28 0.0 1.0 1.0 |
| Metabolism of nitric oxide nos3 activation and regulation 0 10 0.0 1.0 1.0 |
| G protein activation 1 13 3.324631860776439 0.27596662529306126 1.0 P62879 |
| Formation of the beta catenin tcf transactivating complex 0 38 0.0 1.0 1.0 |
| Wnt mediated activation of dvl 0 8 0.0 1.0 1.0 |
| Tcf dependent signaling in response to wnt 3 142 0.8569306498121341 0.6811167378879559 1.0 P25787,P49720,P49721 |
| Fcgamma receptor fcgr dependent phagocytosis 4 72 2.362027737924438 0.10009342067361579 1.0 O15143,P12931,Q8IV08,Q9UQB8 |
| Gene silencing by rna 2 75 1.0906981882456916 0.5525895141700823 1.0 P55735,P62875 |
| Fcgr activation 1 5 9.981927710843374 0.1167524715539159 1.0 P12931 |
| Yap1 and wwtr1 taz stimulated gene expression 0 10 0.0 1.0 1.0 |
| Basigin interactions 0 16 0.0 1.0 1.0 |
| Pecam1 interactions 1 9 4.988955823293173 0.20029633215213802 1.0 P12931 |
| Regulation of gene expression in early pancreatic precursor cells 0 3 0.0 1.0 1.0 |
| Regulation of gene expression in beta cells 0 12 0.0 1.0 1.0 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0 10 0.0 1.0 1.0 |
| Glutamate neurotransmitter release cycle 0 17 0.0 1.0 1.0 |
| Metabolism of amine derived hormones 0 1 0.0 1.0 1.0 |
| Nf kb is activated and signals survival 0 11 0.0 1.0 1.0 |
| P75ntr recruits signalling complexes 0 11 0.0 1.0 1.0 |
| Nrif signals cell death from the nucleus 0 14 0.0 1.0 1.0 |
| Nade modulates death signalling 1 5 9.981927710843374 0.1167524715539159 1.0 P42575 |
| Cell death signalling via nrage nrif and nade 1 63 0.6402383728462236 0.7917073692554857 1.0 P42575 |
| Linoleic acid la metabolism 0 7 0.0 1.0 1.0 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 1 12 3.6272362175976633 0.25774553170225967 1.0 P09110 |
| Regulation of pyruvate dehydrogenase pdh complex 0 16 0.0 1.0 1.0 |
| Copii mediated vesicle transport 2 55 1.5053256238587949 0.39210442689642766 1.0 P55735,Q12907 |
| Microrna mirna biogenesis 1 24 1.7326698096734765 0.4492542995146525 1.0 P62875 |
| Nostrin mediated enos trafficking 0 3 0.0 1.0 1.0 |
| Enos activation 0 7 0.0 1.0 1.0 |
| Role of phospholipids in phagocytosis 1 16 2.6589022757697456 0.3279997416386323 1.0 Q8IV08 |
| Acetylcholine binding and downstream events 0 2 0.0 1.0 1.0 |
| Norepinephrine neurotransmitter release cycle 0 12 0.0 1.0 1.0 |
| Serotonin neurotransmitter release cycle 0 14 0.0 1.0 1.0 |
| Removal of aminoterminal propeptides from gamma carboxylated proteins 0 4 0.0 1.0 1.0 |
| Recycling of bile acids and salts 0 6 0.0 1.0 1.0 |
| Activation of matrix metalloproteinases 0 6 0.0 1.0 1.0 |
| Transport of mature mrnas derived from intronless transcripts 1 43 0.9470262000382482 0.6568914933439602 1.0 P55735 |
| Transport of the slbp dependant mature mrna 1 36 1.1372346528973034 0.5914976917658876 1.0 P55735 |
| Grb7 events in erbb2 signaling 0 2 0.0 1.0 1.0 |
| Metabolism of nucleotides 3 82 1.5169886742171885 0.3261957373675167 1.0 Q13232,Q9H773,Q9Y3D8 |
| Gap junction trafficking and regulation 1 28 1.475383013535624 0.5014414780701414 1.0 P12931 |
| Telomere maintenance 2 74 1.105958781362007 0.5452961463113951 1.0 P62875,Q9NPE3 |
| Signaling by notch 4 152 1.076466710613052 0.5144420239465038 1.0 P25787,P49720,P49721,Q9H488 |
| Downregulation of erbb2 erbb3 signaling 0 10 0.0 1.0 1.0 |
| Polo like kinase mediated events 1 16 2.6589022757697456 0.3279997416386323 1.0 P14635 |
| Fibronectin matrix formation 0 3 0.0 1.0 1.0 |
| Elastic fibre formation 0 23 0.0 1.0 1.0 |
| Glutathione conjugation 1 21 1.9931726907630523 0.4065747127007614 1.0 P78417 |
| Glucuronidation 1 4 13.310575635876841 0.09454246530551126 1.0 Q9NUJ1 |
| Cytosolic sulfonation of small molecules 1 14 3.068582020389249 0.2937421672442234 1.0 Q96IU4 |
| Transcription of e2f targets under negative control by dream complex 0 19 0.0 1.0 1.0 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0 16 0.0 1.0 1.0 |
| Gamma carboxylation transport and amino terminal cleavage of proteins 0 5 0.0 1.0 1.0 |
| G0 and early g1 0 26 0.0 1.0 1.0 |
| Zbp1 dai mediated induction of type i ifns 1 18 2.3456177651783605 0.3606019508791212 1.0 Q13546 |
| Sulfide oxidation to sulfate 1 5 9.981927710843374 0.1167524715539159 1.0 Q9UBX3 |
| Ampk inhibits chrebp transcriptional activation activity 0 7 0.0 1.0 1.0 |
| Triglyceride catabolism 0 13 0.0 1.0 1.0 |
| Glucagon signaling in metabolic regulation 1 21 1.9931726907630523 0.4065747127007614 1.0 P62879 |
| Pka mediated phosphorylation of key metabolic factors 0 4 0.0 1.0 1.0 |
| Formation of atp by chemiosmotic coupling 1 14 3.068582020389249 0.2937421672442234 1.0 O75964 |
| Tandem pore domain potassium channels 0 2 0.0 1.0 1.0 |
| Post translational modification synthesis of gpi anchored proteins 0 32 0.0 1.0 1.0 |
| Glycosaminoglycan metabolism 3 70 1.7908634962837633 0.2458623134324377 1.0 O43505,P16278,P54802 |
| Host interactions of hiv factors 4 116 1.4277003484320558 0.317240385521931 1.0 P25787,P49720,P49721,P55735 |
| Hiv infection 7 213 1.3620200567341882 0.26824650354955604 1.0 O43148,P25787,P49720,P49721,P55735,P62875,Q8WUX9 |
| Attachment of gpi anchor to upar 0 7 0.0 1.0 1.0 |
| Synthesis of glycosylphosphatidylinositol gpi 0 12 0.0 1.0 1.0 |
| Golgi cisternae pericentriolar stack reorganization 1 14 3.068582020389249 0.2937421672442234 1.0 P14635 |
| Early phase of hiv life cycle 0 13 0.0 1.0 1.0 |
| Integration of provirus 0 9 0.0 1.0 1.0 |
| Budding and maturation of hiv virion 1 27 1.5322829780661107 0.48887573248844235 1.0 Q8WUX9 |
| Hiv life cycle 4 144 1.1389082462253195 0.4721947697371172 1.0 O43148,P55735,P62875,Q8WUX9 |
| Sperm motility and taxes 0 1 0.0 1.0 1.0 |
| Acrosome reaction and sperm oocyte membrane binding 0 1 0.0 1.0 1.0 |
| Irf3 mediated activation of type 1 ifn 0 3 0.0 1.0 1.0 |
| Integration of energy metabolism 2 71 1.1543945769050958 0.5229251953532954 1.0 P62879,P63096 |
| Signaling by activin 0 9 0.0 1.0 1.0 |
| Meiosis 1 54 0.7496400697128135 0.7392235469698557 1.0 Q9UH99 |
| Reproduction 1 57 0.7092656339644291 0.758038297770574 1.0 Q9UH99 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0 7 0.0 1.0 1.0 |
| Alpha defensins 0 1 0.0 1.0 1.0 |
| Defensins 0 1 0.0 1.0 1.0 |
| Translocation of slc2a4 glut4 to the plasma membrane 0 66 0.0 1.0 1.0 |
| Collagen degradation 0 21 0.0 1.0 1.0 |
| Regulation of signaling by nodal 0 3 0.0 1.0 1.0 |
| Regulation of kit signaling 1 12 3.6272362175976633 0.25774553170225967 1.0 P12931 |
| Signaling by scf kit 1 31 1.3274431057563587 0.5373222521600443 1.0 P12931 |
| Rora activates gene expression 0 17 0.0 1.0 1.0 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0 21 0.0 1.0 1.0 |
| Formation of fibrin clot clotting cascade 1 9 4.988955823293173 0.20029633215213802 1.0 P42785 |
| Common pathway of fibrin clot formation 0 5 0.0 1.0 1.0 |
| Intrinsic pathway of fibrin clot formation 1 7 6.653279785809906 0.15955769838061679 1.0 P42785 |
| Extrinsic pathway of fibrin clot formation 0 1 0.0 1.0 1.0 |
| Caspase activation via death receptors in the presence of ligand 1 11 3.9903614457831327 0.23906776451302655 1.0 Q13546 |
| Apoptosis induced dna fragmentation 0 11 0.0 1.0 1.0 |
| Activation of puma and translocation to mitochondria 0 8 0.0 1.0 1.0 |
| Elevation of cytosolic ca2 levels 0 6 0.0 1.0 1.0 |
| Degradation of the extracellular matrix 0 56 0.0 1.0 1.0 |
| Cell cell communication 4 79 2.1400542005420053 0.12863209279328225 1.0 P12931,Q15404,Q9NVD7,Q9Y624 |
| Extracellular matrix organization 1 131 0.30324374420759964 0.9621170154486476 1.0 Q9Y624 |
| Reversible hydration of carbon dioxide 0 2 0.0 1.0 1.0 |
| Dag and ip3 signaling 0 30 0.0 1.0 1.0 |
| Phospholipid metabolism 4 156 1.0477107402652974 0.5349805913613837 1.0 Q8IV08,Q8NF37,Q8WUK0,Q9BTU6 |
| Pi metabolism 1 71 0.5666092943201377 0.8294508517100334 1.0 Q9BTU6 |
| Inositol phosphate metabolism 1 40 1.020183297291731 0.6302503007248048 1.0 Q92551 |
| Synthesis of pips at the er membrane 0 5 0.0 1.0 1.0 |
| Synthesis of pi 0 5 0.0 1.0 1.0 |
| Synthesis of pe 0 12 0.0 1.0 1.0 |
| Glycerophospholipid biosynthesis 3 86 1.4432954490024876 0.35315852316499907 1.0 Q8IV08,Q8NF37,Q8WUK0 |
| Synthesis of pc 1 22 1.8980684643335246 0.42115518658714335 1.0 Q8NF37 |
| Synthesis of pa 1 25 1.6603078982597055 0.4627901258069825 1.0 Q8NF37 |
| Mitochondrial iron sulfur cluster biogenesis 0 12 0.0 1.0 1.0 |
| Hydrolysis of lpc 0 3 0.0 1.0 1.0 |
| Acyl chain remodelling of pg 1 7 6.653279785809906 0.15955769838061679 1.0 Q8NF37 |
| Acyl chain remodelling of pi 0 4 0.0 1.0 1.0 |
| Acyl chain remodeling of dag and tag 0 2 0.0 1.0 1.0 |
| Acyl chain remodelling of pe 0 8 0.0 1.0 1.0 |
| Acyl chain remodelling of ps 0 9 0.0 1.0 1.0 |
| Acyl chain remodeling of cl 0 5 0.0 1.0 1.0 |
| Acyl chain remodelling of pc 1 9 4.988955823293173 0.20029633215213802 1.0 Q8NF37 |
| Collagen formation 0 44 0.0 1.0 1.0 |
| Egfr transactivation by gastrin 0 7 0.0 1.0 1.0 |
| Chrebp activates metabolic gene expression 0 8 0.0 1.0 1.0 |
| Heparan sulfate heparin hs gag metabolism 2 32 2.6655913978494623 0.18456745178931963 1.0 P16278,P54802 |
| Telomere c strand lagging strand synthesis 0 37 0.0 1.0 1.0 |
| Processive synthesis on the c strand of the telomere 0 21 0.0 1.0 1.0 |
| Polymerase switching on the c strand of the telomere 0 28 0.0 1.0 1.0 |
| Glutathione synthesis and recycling 0 8 0.0 1.0 1.0 |
| Transport and synthesis of paps 0 4 0.0 1.0 1.0 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 3 68 1.8463407038305824 0.23275165888233573 1.0 P25787,P49720,P49721 |
| Apc c mediated degradation of cell cycle proteins 4 81 2.0840460352655477 0.13735030663483583 1.0 P14635,P25787,P49720,P49721 |
| Apc c cdc20 mediated degradation of cyclin b 1 23 1.8116100766703176 0.4353788157626653 1.0 P14635 |
| Alternative complement activation 0 1 0.0 1.0 1.0 |
| Telomere extension by telomerase 1 21 1.9931726907630523 0.4065747127007614 1.0 Q9NPE3 |
| P38mapk events 1 13 3.324631860776439 0.27596662529306126 1.0 P12931 |
| Arms mediated activation 0 5 0.0 1.0 1.0 |
| Signaling by tgf beta receptor complex 1 67 0.6011926493854205 0.8115177708405034 1.0 Q9Y624 |
| Regulation of glucokinase by glucokinase regulatory protein 1 31 1.3274431057563587 0.5373222521600443 1.0 P55735 |
| Adenylate cyclase inhibitory pathway 1 6 7.9847389558232935 0.1384198135311803 1.0 P63096 |
| Adenylate cyclase activating pathway 0 3 0.0 1.0 1.0 |
| Prolonged erk activation events 0 12 0.0 1.0 1.0 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 2 57 1.4502932551319647 0.4094079381471642 1.0 Q13546,Q15366 |
| Ticam1 rip1 mediated ikk complex recruitment 1 16 2.6589022757697456 0.3279997416386323 1.0 Q13546 |
| Telomere c strand synthesis initiation 0 13 0.0 1.0 1.0 |
| Toll like receptor cascades 2 103 0.786090705844778 0.7232667650490989 1.0 Q13546,Q6SZW1 |
| Activation of c3 and c5 0 1 0.0 1.0 1.0 |
| Assembly of the hiv virion 0 15 0.0 1.0 1.0 |
| Rip mediated nfkb activation via zbp1 1 16 2.6589022757697456 0.3279997416386323 1.0 Q13546 |
| Extension of telomeres 1 52 0.7791952122214347 0.7258778528724746 1.0 Q9NPE3 |
| Nuclear import of rev protein 1 34 1.2064013630278692 0.5706303062959026 1.0 P55735 |
| Apobec3g mediated resistance to hiv 1 infection 0 4 0.0 1.0 1.0 |
| Shc1 events in egfr signaling 0 7 0.0 1.0 1.0 |
| Gab1 signalosome 1 10 4.4341811691209285 0.2199219252501269 1.0 P12931 |
| Darpp 32 events 0 20 0.0 1.0 1.0 |
| Spry regulation of fgf signaling 1 14 3.068582020389249 0.2937421672442234 1.0 P12931 |
| Apc cdc20 mediated degradation of nek2a 0 25 0.0 1.0 1.0 |
| Chondroitin sulfate dermatan sulfate metabolism 0 32 0.0 1.0 1.0 |
| Signaling by egfr 2 40 2.102716468590832 0.25702964942480505 1.0 P12931,P42566 |
| Retrograde neurotrophin signalling 0 12 0.0 1.0 1.0 |
| Interactions of rev with host cellular proteins 1 37 1.105533244087461 0.6015494217836266 1.0 P55735 |
| Unwinding of dna 0 12 0.0 1.0 1.0 |
| Phosphorylation of emi1 1 6 7.9847389558232935 0.1384198135311803 1.0 P14635 |
| Phosphorylation of the apc c 1 20 2.098287888395688 0.39162847837900855 1.0 P14635 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0 20 0.0 1.0 1.0 |
| Activation of atr in response to replication stress 1 38 1.0755454249430152 0.6113547810413322 1.0 O43929 |
| Interactions of vpr with host cellular proteins 1 37 1.105533244087461 0.6015494217836266 1.0 P55735 |
| Plasma lipoprotein assembly remodeling and clearance 2 40 2.102716468590832 0.25702964942480505 1.0 P61916,Q8WTV0 |
| Pp2a mediated dephosphorylation of key metabolic factors 0 6 0.0 1.0 1.0 |
| Neurotoxicity of clostridium toxins 0 8 0.0 1.0 1.0 |
| Nod1 2 signaling pathway 1 30 1.3733554909292343 0.5256573230515567 1.0 P42575 |
| Myd88 independent tlr4 cascade 2 78 1.0473259762308997 0.5739728683048202 1.0 Q13546,Q6SZW1 |
| Voltage gated potassium channels 0 2 0.0 1.0 1.0 |
| Sphingolipid de novo biosynthesis 1 29 1.4225473321858864 0.5136995062503719 1.0 Q96G23 |
| Synthesis of pips at the late endosome membrane 0 10 0.0 1.0 1.0 |
| Synthesis of pips at the early endosome membrane 1 16 2.6589022757697456 0.3279997416386323 1.0 Q9BTU6 |
| Synthesis of pips at the golgi membrane 1 15 2.849110728628801 0.31108300972667774 1.0 Q9BTU6 |
| Synthesis of pips at the plasma membrane 1 47 0.8643268727082242 0.6894621252275617 1.0 Q9BTU6 |
| Regulation of cholesterol biosynthesis by srebp srebf 2 55 1.5053256238587949 0.39210442689642766 1.0 P48449,Q03426 |
| Mtor signalling 1 39 1.04713591206933 0.6209197844592236 1.0 P62753 |
| Collagen biosynthesis and modifying enzymes 0 30 0.0 1.0 1.0 |
| The role of nef in hiv 1 replication and disease pathogenesis 0 20 0.0 1.0 1.0 |
| Nef and signal transduction 0 4 0.0 1.0 1.0 |
| Nef mediated downregulation of mhc class i complex cell surface expression 0 9 0.0 1.0 1.0 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0 16 0.0 1.0 1.0 |
| 2 ltr circle formation 0 7 0.0 1.0 1.0 |
| Pka activation in glucagon signalling 0 12 0.0 1.0 1.0 |
| Signaling by egfr in cancer 0 17 0.0 1.0 1.0 |
| Cell cycle 18 613 1.2193422196464794 0.24623568829098447 1.0 O43237,O43929,O94927,P12931,P14635,P25787,P49720,P49721,P55735,P62875,Q13561,Q8WUX9,Q92674,Q96FJ2,Q9NPE3,Q9NWV8,Q9UH99,Q9UQ84 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 2 29 2.9626642771804064 0.15821668919150678 1.0 O60725,Q8NBJ7 |
| Mitochondrial uncoupling 0 1 0.0 1.0 1.0 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 2 42 1.9971774193548386 0.27533025106482545 1.0 P09601,P42575 |
| Mtorc1 mediated signalling 1 23 1.8116100766703176 0.4353788157626653 1.0 P62753 |
| Signaling by ntrks 1 102 0.3914668575291264 0.9215220184812024 1.0 P12931 |
| Viral messenger rna synthesis 2 44 1.901689708141321 0.29360808483863915 1.0 P55735,P62875 |
| Ns1 mediated effects on host pathways 1 40 1.020183297291731 0.6302503007248048 1.0 P55735 |
| Export of viral ribonucleoproteins from nucleus 1 32 1.2844928099494752 0.548701439263177 1.0 P55735 |
| Inwardly rectifying k channels 1 12 3.6272362175976633 0.25774553170225967 1.0 P62879 |
| Potassium channels 1 15 2.849110728628801 0.31108300972667774 1.0 P62879 |
| Toll like receptor tlr1 tlr2 cascade 0 70 0.0 1.0 1.0 |
| Toll like receptor 9 tlr9 cascade 0 75 0.0 1.0 1.0 |
| Trafficking and processing of endosomal tlr 0 8 0.0 1.0 1.0 |
| The fatty acid cycling model 0 1 0.0 1.0 1.0 |
| Nef mediated cd4 down regulation 0 7 0.0 1.0 1.0 |
| Hiv elongation arrest and recovery 1 32 1.2844928099494752 0.548701439263177 1.0 P62875 |
| Abortive elongation of hiv 1 transcript in the absence of tat 1 23 1.8116100766703176 0.4353788157626653 1.0 P62875 |
| Transcription of the hiv genome 2 67 1.2259305210918114 0.491975530136046 1.0 O43148,P62875 |
| Hiv transcription elongation 1 42 0.9702223528259379 0.6482306364536417 1.0 P62875 |
| Hiv transcription initiation 1 45 0.9037970062066447 0.6735811793023442 1.0 P62875 |
| Signalling to ras 1 16 2.6589022757697456 0.3279997416386323 1.0 P12931 |
| Terminal pathway of complement 0 1 0.0 1.0 1.0 |
| Initial triggering of complement 0 1 0.0 1.0 1.0 |
| Complement cascade 0 10 0.0 1.0 1.0 |
| The activation of arylsulfatases 1 8 5.70223752151463 0.1801790130745941 1.0 Q8NBJ7 |
| Caspase activation via extrinsic apoptotic signalling pathway 1 18 2.3456177651783605 0.3606019508791212 1.0 Q13546 |
| The retinoid cycle in cones daylight vision 0 1 0.0 1.0 1.0 |
| Notch2 intracellular domain regulates transcription 0 7 0.0 1.0 1.0 |
| Activation of rac1 0 12 0.0 1.0 1.0 |
| Regulation of gene expression by hypoxia inducible factor 0 5 0.0 1.0 1.0 |
| Sodium coupled phosphate cotransporters 0 2 0.0 1.0 1.0 |
| Multifunctional anion exchangers 0 3 0.0 1.0 1.0 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0 27 0.0 1.0 1.0 |
| Sirt1 negatively regulates rrna expression 0 18 0.0 1.0 1.0 |
| Small interfering rna sirna biogenesis 0 9 0.0 1.0 1.0 |
| Cation coupled chloride cotransporters 0 4 0.0 1.0 1.0 |
| Regulation of commissural axon pathfinding by slit and robo 1 7 6.653279785809906 0.15955769838061679 1.0 P12931 |
| Arachidonate production from dag 0 4 0.0 1.0 1.0 |
| Sodium calcium exchangers 0 3 0.0 1.0 1.0 |
| Metal ion slc transporters 0 15 0.0 1.0 1.0 |
| Slc mediated transmembrane transport 2 101 0.8021342456826328 0.7131623095713835 1.0 Q70HW3,Q9UBX3 |
| Transport of vitamins nucleosides and related molecules 0 21 0.0 1.0 1.0 |
| Transport of inorganic cations anions and amino acids oligopeptides 2 44 1.901689708141321 0.29360808483863915 1.0 Q70HW3,Q9UBX3 |
| Bicarbonate transporters 0 4 0.0 1.0 1.0 |
| Transport of bile salts and organic acids metal ions and amine compounds 0 32 0.0 1.0 1.0 |
| Regulation of insulin secretion 2 48 1.7356241234221599 0.3299370460914438 1.0 P62879,P63096 |
| Sodium proton exchangers 0 4 0.0 1.0 1.0 |
| Inactivation of cdc42 and rac1 0 8 0.0 1.0 1.0 |
| Organic anion transporters 1 3 19.967871485943775 0.07177625956655588 1.0 Q9UBX3 |
| Role of abl in robo slit signaling 0 9 0.0 1.0 1.0 |
| Depolymerisation of the nuclear lamina 1 16 2.6589022757697456 0.3279997416386323 1.0 P14635 |
| Binding of tcf lef ctnnb1 to target gene promoters 0 7 0.0 1.0 1.0 |
| Unblocking of nmda receptors glutamate binding and activation 1 9 4.988955823293173 0.20029633215213802 1.0 Q92796 |
| Recycling pathway of l1 1 41 0.994578313253012 0.6393520558322405 1.0 P12931 |
| Zinc efflux and compartmentalization by the slc30 family 0 5 0.0 1.0 1.0 |
| Zinc transporters 0 12 0.0 1.0 1.0 |
| Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0 6 0.0 1.0 1.0 |
| Proton coupled monocarboxylate transport 0 4 0.0 1.0 1.0 |
| Golgi associated vesicle biogenesis 1 55 0.735683474639298 0.7456516788145606 1.0 Q13492 |
| Lysosome vesicle biogenesis 0 32 0.0 1.0 1.0 |
| Platelet sensitization by ldl 0 15 0.0 1.0 1.0 |
| Passive transport by aquaporins 0 1 0.0 1.0 1.0 |
| Vasopressin regulates renal water homeostasis via aquaporins 1 25 1.6603078982597055 0.4627901258069825 1.0 P62879 |
| Gp1b ix v activation signalling 1 7 6.653279785809906 0.15955769838061679 1.0 P12931 |
| Mrna decay by 5 to 3 exoribonuclease 0 15 0.0 1.0 1.0 |
| Signaling by erbb2 in cancer 0 17 0.0 1.0 1.0 |
| Deadenylation of mrna 0 26 0.0 1.0 1.0 |
| Deadenylation dependent mrna decay 2 57 1.4502932551319647 0.4094079381471642 1.0 Q969T7,Q9NQT5 |
| Thromboxane signalling through tp receptor 1 15 2.849110728628801 0.31108300972667774 1.0 P62879 |
| Synthesis secretion and deacylation of ghrelin 0 5 0.0 1.0 1.0 |
| Cell cell junction organization 1 31 1.3274431057563587 0.5373222521600443 1.0 Q9Y624 |
| Nectin necl trans heterodimerization 0 5 0.0 1.0 1.0 |
| Glucagon type ligand receptors 1 13 3.324631860776439 0.27596662529306126 1.0 P62879 |
| Ca2 pathway 1 45 0.9037970062066447 0.6735811793023442 1.0 P62879 |
| Sumoylation of sumoylation proteins 1 35 1.1708008504606662 0.5811934260914344 1.0 P55735 |
| Sialic acid metabolism 1 16 2.6589022757697456 0.3279997416386323 1.0 P16278 |
| Sema4d in semaphorin signaling 0 23 0.0 1.0 1.0 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0 9 0.0 1.0 1.0 |
| Incretin synthesis secretion and inactivation 0 14 0.0 1.0 1.0 |
| Free fatty acids regulate insulin secretion 0 8 0.0 1.0 1.0 |
| Circadian clock 1 55 0.735683474639298 0.7456516788145606 1.0 P43490 |
| Regulation of lipid metabolism by pparalpha 3 95 1.3009153318077804 0.4131831186078936 1.0 P11474,P23786,Q71SY5 |
| Cellular response to hypoxia 3 59 2.145026026604974 0.17574902591021677 1.0 P25787,P49720,P49721 |
| Acetylcholine regulates insulin secretion 0 8 0.0 1.0 1.0 |
| Crmps in sema3a signaling 1 12 3.6272362175976633 0.25774553170225967 1.0 O14786 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 1 10 4.4341811691209285 0.2199219252501269 1.0 O14786 |
| Sema3a pak dependent axon repulsion 1 13 3.324631860776439 0.27596662529306126 1.0 O14786 |
| Trafficking of ampa receptors 0 20 0.0 1.0 1.0 |
| G protein beta gamma signalling 1 22 1.8980684643335246 0.42115518658714335 1.0 P62879 |
| Muscle contraction 1 83 0.4831031442844549 0.8736769220313676 1.0 P23634 |
| Eph ephrin mediated repulsion of cells 1 43 0.9470262000382482 0.6568914933439602 1.0 P12931 |
| Ephrin signaling 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Pcp ce pathway 3 78 1.5985425101214574 0.29923050214098046 1.0 P25787,P49720,P49721 |
| Zinc influx into cells by the slc39 gene family 0 7 0.0 1.0 1.0 |
| Sumoylation of intracellular receptors 0 18 0.0 1.0 1.0 |
| G alpha 12 13 signalling events 1 57 0.7092656339644291 0.758038297770574 1.0 P62879 |
| Tight junction interactions 1 11 3.9903614457831327 0.23906776451302655 1.0 Q9Y624 |
| Lysosphingolipid and lpa receptors 0 3 0.0 1.0 1.0 |
| Ncam1 interactions 0 15 0.0 1.0 1.0 |
| Adherens junctions interactions 0 18 0.0 1.0 1.0 |
| Role of second messengers in netrin 1 signaling 0 3 0.0 1.0 1.0 |
| Caspase activation via dependence receptors in the absence of ligand 0 7 0.0 1.0 1.0 |
| Netrin mediated repulsion signals 1 5 9.981927710843374 0.1167524715539159 1.0 P12931 |
| Dcc mediated attractive signaling 1 13 3.324631860776439 0.27596662529306126 1.0 P12931 |
| G alpha z signalling events 2 28 3.076923076923077 0.14960060163762684 1.0 P62879,P63096 |
| Cgmp effects 0 7 0.0 1.0 1.0 |
| Platelet calcium homeostasis 1 13 3.324631860776439 0.27596662529306126 1.0 P23634 |
| Reduction of cytosolic ca levels 1 7 6.653279785809906 0.15955769838061679 1.0 P23634 |
| Platelet homeostasis 2 51 1.6288676761026992 0.35685011838570857 1.0 P23634,P62879 |
| Nucleotide like purinergic receptors 0 1 0.0 1.0 1.0 |
| P2y receptors 0 1 0.0 1.0 1.0 |
| Trafficking of glur2 containing ampa receptors 0 11 0.0 1.0 1.0 |
| Other semaphorin interactions 0 7 0.0 1.0 1.0 |
| Sema4d induced cell migration and growth cone collapse 0 18 0.0 1.0 1.0 |
| Sema4d mediated inhibition of cell attachment and migration 0 8 0.0 1.0 1.0 |
| G alpha q signalling events 1 66 0.6105035526722273 0.8067484836572784 1.0 P62879 |
| Na cl dependent neurotransmitter transporters 0 4 0.0 1.0 1.0 |
| Creb1 phosphorylation through the activation of adenylate cyclase 0 9 0.0 1.0 1.0 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0 7 0.0 1.0 1.0 |
| Defective c1galt1c1 causes tnps 0 2 0.0 1.0 1.0 |
| Defective lfng causes scdo3 0 3 0.0 1.0 1.0 |
| Defective galnt3 causes hftc 0 1 0.0 1.0 1.0 |
| Gpcr ligand binding 3 46 2.7971942378307126 0.10259295039812891 1.0 P07602,P62879,Q9NZJ7 |
| Presynaptic function of kainate receptors 1 13 3.324631860776439 0.27596662529306126 1.0 P62879 |
| Prolactin receptor signaling 0 9 0.0 1.0 1.0 |
| Signaling by ctnnb1 phospho site mutants 0 15 0.0 1.0 1.0 |
| Signaling by wnt in cancer 0 25 0.0 1.0 1.0 |
| Sumoylation of immune response proteins 0 10 0.0 1.0 1.0 |
| Sumoylation of dna methylation proteins 0 16 0.0 1.0 1.0 |
| Repression of wnt target genes 0 13 0.0 1.0 1.0 |
| Regulation of fzd by ubiquitination 0 9 0.0 1.0 1.0 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 0 24 0.0 1.0 1.0 |
| Degradation of dvl 3 50 2.55810147299509 0.12361304926291004 1.0 P25787,P49720,P49721 |
| Degradation of axin 3 48 2.6723346828609986 0.11291463467421847 1.0 P25787,P49720,P49721 |
| Sumoylation of dna replication proteins 1 46 0.8836233824185632 0.6816202597135863 1.0 P55735 |
| Asymmetric localization of pcp proteins 3 54 2.356513455584663 0.14604051425702808 1.0 P25787,P49720,P49721 |
| Sumoylation of rna binding proteins 1 47 0.8643268727082242 0.6894621252275617 1.0 P55735 |
| Thrombin signalling through proteinase activated receptors pars 2 21 4.213497453310696 0.09270379205394921 1.0 P12931,P62879 |
| Wnt5a dependent internalization of fzd4 0 13 0.0 1.0 1.0 |
| Sumoylation of chromatin organization proteins 1 58 0.696751919960544 0.7640044113333799 1.0 P55735 |
| Interleukin 3 interleukin 5 and gm csf signaling 0 31 0.0 1.0 1.0 |
| O linked glycosylation 1 35 1.1708008504606662 0.5811934260914344 1.0 O43505 |
| Signaling by lrp5 mutants 0 2 0.0 1.0 1.0 |
| Bmal1 clock npas2 activates circadian gene expression 1 20 2.098287888395688 0.39162847837900855 1.0 P43490 |
| Uptake and function of diphtheria toxin 0 5 0.0 1.0 1.0 |
| Dna methylation 0 14 0.0 1.0 1.0 |
| N glycan trimming in the er and calnexin calreticulin cycle 0 32 0.0 1.0 1.0 |
| Diseases of immune system 0 15 0.0 1.0 1.0 |
| Myogenesis 0 22 0.0 1.0 1.0 |
| Toxicity of botulinum toxin type d botd 0 3 0.0 1.0 1.0 |
| Negative epigenetic regulation of rrna expression 1 61 0.6617135207496653 0.7810378001033369 1.0 P62875 |
| B wich complex positively regulates rrna expression 1 45 0.9037970062066447 0.6735811793023442 1.0 P62875 |
| Positive epigenetic regulation of rrna expression 1 60 0.6729970730379143 0.7755006212469995 1.0 P62875 |
| Miscellaneous transport and binding events 0 17 0.0 1.0 1.0 |
| Vegfr2 mediated cell proliferation 1 15 2.849110728628801 0.31108300972667774 1.0 P12931 |
| Vegfr2 mediated vascular permeability 0 22 0.0 1.0 1.0 |
| Regulated necrosis 2 42 1.9971774193548386 0.27533025106482545 1.0 Q13546,Q8WUX9 |
| Ripk1 mediated regulated necrosis 1 26 1.5937349397590361 0.47599457655385613 1.0 Q13546 |
| Uptake and function of anthrax toxins 0 10 0.0 1.0 1.0 |
| Antiviral mechanism by ifn stimulated genes 1 73 0.5507585899152164 0.8377694600101696 1.0 P55735 |
| O glycosylation of tsr domain containing proteins 0 5 0.0 1.0 1.0 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 0 12 0.0 1.0 1.0 |
| Epha mediated growth cone collapse 1 23 1.8116100766703176 0.4353788157626653 1.0 P12931 |
| Mitotic g1 phase and g1 s transition 6 143 1.7606198396553787 0.13931799022110225 1.0 O43929,P12931,P14635,P25787,P49720,P49721 |
| Transcriptional regulation of pluripotent stem cells 0 16 0.0 1.0 1.0 |
| Fertilization 0 3 0.0 1.0 1.0 |
| Meiotic synapsis 1 31 1.3274431057563587 0.5373222521600443 1.0 Q9UH99 |
| Ros and rns production in phagocytes 1 16 2.6589022757697456 0.3279997416386323 1.0 Q93050 |
| Synthesis of udp n acetyl glucosamine 1 8 5.70223752151463 0.1801790130745941 1.0 Q9UJ70 |
| Synthesis of gdp mannose 0 5 0.0 1.0 1.0 |
| Signaling by fgfr in disease 1 48 0.8458514910706656 0.6971115950162535 1.0 P62875 |
| Synthesis of dolichyl phosphate 1 5 9.981927710843374 0.1167524715539159 1.0 Q86YN1 |
| Signaling by erbb2 1 37 1.105533244087461 0.6015494217836266 1.0 P12931 |
| Type i hemidesmosome assembly 0 9 0.0 1.0 1.0 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 0 25 0.0 1.0 1.0 |
| Aquaporin mediated transport 1 26 1.5937349397590361 0.47599457655385613 1.0 P62879 |
| Smooth muscle contraction 0 28 0.0 1.0 1.0 |
| Signal transduction by l1 1 20 2.098287888395688 0.39162847837900855 1.0 O14786 |
| Interaction between l1 and ankyrins 0 12 0.0 1.0 1.0 |
| Formyl peptide receptors bind formyl peptides and many other ligands 0 3 0.0 1.0 1.0 |
| Rsk activation 0 7 0.0 1.0 1.0 |
| Ras activation upon ca2 influx through nmda receptor 1 13 3.324631860776439 0.27596662529306126 1.0 Q92796 |
| Activation of nmda receptors and postsynaptic events 2 68 1.2072336265884653 0.49983079895380533 1.0 P12931,Q92796 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 1 21 1.9931726907630523 0.4065747127007614 1.0 Q92796 |
| Interleukin 1 family signaling 3 95 1.3009153318077804 0.4131831186078936 1.0 P25787,P49720,P49721 |
| Mitotic g2 g2 m phases 6 186 1.3341530054644808 0.3057536501363799 1.0 O94927,P14635,P25787,P49720,P49721,Q13561 |
| Cell junction organization 3 54 2.356513455584663 0.14604051425702808 1.0 Q15404,Q9NVD7,Q9Y624 |
| Chl1 interactions 1 7 6.653279785809906 0.15955769838061679 1.0 O14786 |
| Interleukin 2 family signaling 0 21 0.0 1.0 1.0 |
| Signaling by the b cell receptor bcr 3 91 1.3605999263894 0.3866675549018741 1.0 P25787,P49720,P49721 |
| Ionotropic activity of kainate receptors 1 3 19.967871485943775 0.07177625956655588 1.0 Q92796 |
| Ksrp khsrp binds and destabilizes mrna 1 17 2.4924698795180724 0.34450269493005076 1.0 Q9NQT5 |
| Regulation of mrna stability by proteins that bind au rich elements 4 79 2.1400542005420053 0.12863209279328225 1.0 P25787,P49720,P49721,Q9NQT5 |
| Hur elavl1 binds and stabilizes mrna 0 7 0.0 1.0 1.0 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 1 17 2.4924698795180724 0.34450269493005076 1.0 Q9NQT5 |
| Auf1 hnrnp d0 binds and destabilizes mrna 3 48 2.6723346828609986 0.11291463467421847 1.0 P25787,P49720,P49721 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 1 17 2.4924698795180724 0.34450269493005076 1.0 Q9NQT5 |
| Activation of the ap 1 family of transcription factors 0 8 0.0 1.0 1.0 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0 18 0.0 1.0 1.0 |
| Activated tak1 mediates p38 mapk activation 0 20 0.0 1.0 1.0 |
| Mapk targets nuclear events mediated by map kinases 0 27 0.0 1.0 1.0 |
| Other interleukin signaling 0 12 0.0 1.0 1.0 |
| Signaling by interleukins 8 248 1.3369146005509642 0.2639599010327692 1.0 O00170,P09601,P25787,P49720,P49721,P78417,Q13126,Q53EL6 |
| Interleukin 1 processing 0 3 0.0 1.0 1.0 |
| Interleukin 17 signaling 0 57 0.0 1.0 1.0 |
| Signaling by nodal 0 12 0.0 1.0 1.0 |
| Neurofascin interactions 0 6 0.0 1.0 1.0 |
| Nrcam interactions 1 7 6.653279785809906 0.15955769838061679 1.0 Q92796 |
| Ephb mediated forward signaling 2 40 2.102716468590832 0.25702964942480505 1.0 O15143,P12931 |
| Prostacyclin signalling through prostacyclin receptor 1 12 3.6272362175976633 0.25774553170225967 1.0 P62879 |
| Constitutive signaling by ligand responsive egfr cancer variants 0 17 0.0 1.0 1.0 |
| Scavenging by class f receptors 0 5 0.0 1.0 1.0 |
| Scavenging by class a receptors 0 10 0.0 1.0 1.0 |
| Erythrocytes take up carbon dioxide and release oxygen 0 4 0.0 1.0 1.0 |
| Ecm proteoglycans 0 37 0.0 1.0 1.0 |
| Non integrin membrane ecm interactions 0 37 0.0 1.0 1.0 |
| Syndecan interactions 0 20 0.0 1.0 1.0 |
| Laminin interactions 0 23 0.0 1.0 1.0 |
| Nuclear envelope ne reassembly 3 71 1.7643486544415337 0.25246138092126835 1.0 P14635,P55735,Q8WUX9 |
| Initiation of nuclear envelope ne reformation 1 20 2.098287888395688 0.39162847837900855 1.0 P14635 |
| Sumoylation 3 155 0.7826017472831878 0.737001569996368 1.0 P14373,P52739,P55735 |
| Activation of nima kinases nek9 nek6 nek7 1 7 6.653279785809906 0.15955769838061679 1.0 P14635 |
| Nuclear envelope breakdown 2 54 1.5344292803970223 0.3833676775949033 1.0 P14635,P55735 |
| Peptide hormone metabolism 0 43 0.0 1.0 1.0 |
| Notch2 activation and transmission of signal to the nucleus 0 16 0.0 1.0 1.0 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 0 8 0.0 1.0 1.0 |
| Pou5f1 oct4 sox2 nanog repress genes related to differentiation 0 6 0.0 1.0 1.0 |
| Fceri mediated nf kb activation 3 68 1.8463407038305824 0.23275165888233573 1.0 P25787,P49720,P49721 |
| Fceri mediated ca 2 mobilization 0 20 0.0 1.0 1.0 |
| Fceri mediated mapk activation 0 24 0.0 1.0 1.0 |
| Sumo is conjugated to e1 uba2 sae1 0 5 0.0 1.0 1.0 |
| Role of lat2 ntal lab on calcium mobilization 0 12 0.0 1.0 1.0 |
| Sumo is transferred from e1 to e2 ube2i ubc9 0 7 0.0 1.0 1.0 |
| Sumoylation of dna damage response and repair proteins 1 76 0.5285676037483267 0.8494956492245809 1.0 P55735 |
| Detoxification of reactive oxygen species 0 24 0.0 1.0 1.0 |
| Defects in vitamin and cofactor metabolism 1 18 2.3456177651783605 0.3606019508791212 1.0 Q96EY8 |
| Defects in cobalamin b12 metabolism 1 10 4.4341811691209285 0.2199219252501269 1.0 Q96EY8 |
| Trp channels 1 7 6.653279785809906 0.15955769838061679 1.0 Q13546 |
| Irf3 mediated induction of type i ifn 0 8 0.0 1.0 1.0 |
| Chromatin modifying enzymes 4 210 0.7688057463098903 0.761733842698859 1.0 O75530,Q01658,Q15906,Q8NB78 |
| Wnt ligand biogenesis and trafficking 0 9 0.0 1.0 1.0 |
| Sumoylation of ubiquitinylation proteins 2 39 2.1597646033129902 0.24788465108468175 1.0 P14373,P55735 |
| Sumoylation of transcription factors 0 18 0.0 1.0 1.0 |
| Glycogen storage diseases 0 10 0.0 1.0 1.0 |
| Processing and activation of sumo 0 10 0.0 1.0 1.0 |
| Rmts methylate histone arginines 0 36 0.0 1.0 1.0 |
| Hats acetylate histones 2 90 0.9034090909090909 0.6519941826074332 1.0 Q01658,Q15906 |
| Hdms demethylate histones 1 25 1.6603078982597055 0.4627901258069825 1.0 Q8NB78 |
| Pkmts methylate histone lysines 1 46 0.8836233824185632 0.6816202597135863 1.0 O75530 |
| Hdacs deacetylate histones 0 40 0.0 1.0 1.0 |
| Regulation of innate immune responses to cytosolic dna 0 11 0.0 1.0 1.0 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0 5 0.0 1.0 1.0 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 0 7 0.0 1.0 1.0 |
| Sumo is proteolytically processed 0 6 0.0 1.0 1.0 |
| Nuclear pore complex npc disassembly 2 36 2.351043643263757 0.22054412764311498 1.0 P14635,P55735 |
| Signaling by notch1 hd domain mutants in cancer 0 9 0.0 1.0 1.0 |
| Stimuli sensing channels 1 38 1.0755454249430152 0.6113547810413322 1.0 Q13546 |
| Establishment of sister chromatid cohesion 0 11 0.0 1.0 1.0 |
| Separation of sister chromatids 7 179 1.6369509043927648 0.15071893588943813 1.0 O43237,P25787,P49720,P49721,P55735,Q92674,Q96FJ2 |
| Mastl facilitates mitotic progression 1 10 4.4341811691209285 0.2199219252501269 1.0 P14635 |
| Fc epsilon receptor fceri signaling 3 108 1.1383458646616542 0.4964084842421358 1.0 P25787,P49720,P49721 |
| The canonical retinoid cycle in rods twilight vision 0 4 0.0 1.0 1.0 |
| Retinoid cycle disease events 0 2 0.0 1.0 1.0 |
| Shc related events triggered by igf1r 0 7 0.0 1.0 1.0 |
| Activation of gene expression by srebf srebp 2 42 1.9971774193548386 0.27533025106482545 1.0 P48449,Q03426 |
| Dap12 signaling 0 19 0.0 1.0 1.0 |
| Methionine salvage pathway 1 6 7.9847389558232935 0.1384198135311803 1.0 Q13126 |
| Metabolism of ingested semet sec mesec into h2se 0 4 0.0 1.0 1.0 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 0 29 0.0 1.0 1.0 |
| Phosphate bond hydrolysis by nudt proteins 0 6 0.0 1.0 1.0 |
| Condensation of prophase chromosomes 1 23 1.8116100766703176 0.4353788157626653 1.0 P14635 |
| Crosslinking of collagen fibrils 0 10 0.0 1.0 1.0 |
| Constitutive signaling by aberrant pi3k in cancer 1 32 1.2844928099494752 0.548701439263177 1.0 P12931 |
| Pi3k akt signaling in cancer 1 58 0.696751919960544 0.7640044113333799 1.0 P12931 |
| Anchoring fibril formation 0 8 0.0 1.0 1.0 |
| Erythrocytes take up oxygen and release carbon dioxide 0 1 0.0 1.0 1.0 |
| Cohesin loading onto chromatin 0 10 0.0 1.0 1.0 |
| Eph ephrin signaling 2 80 1.020264681555004 0.5878117897228861 1.0 O15143,P12931 |
| Activation of the phototransduction cascade 0 2 0.0 1.0 1.0 |
| Condensation of prometaphase chromosomes 1 11 3.9903614457831327 0.23906776451302655 1.0 P14635 |
| Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant 0 4 0.0 1.0 1.0 |
| Insulin processing 0 21 0.0 1.0 1.0 |
| Caspase mediated cleavage of cytoskeletal proteins 0 12 0.0 1.0 1.0 |
| Acetylcholine neurotransmitter release cycle 0 11 0.0 1.0 1.0 |
| Fbxw7 mutants and notch1 in cancer 0 5 0.0 1.0 1.0 |
| Signaling by notch1 pest domain mutants in cancer 0 45 0.0 1.0 1.0 |
| Signaling by leptin 0 8 0.0 1.0 1.0 |
| Regulation of plk1 activity at g2 m transition 3 87 1.4259687680740312 0.3598837636022959 1.0 O94927,P14635,Q13561 |
| Cytosolic iron sulfur cluster assembly 1 13 3.324631860776439 0.27596662529306126 1.0 O76071 |
| Trif mediated programmed cell death 1 4 13.310575635876841 0.09454246530551126 1.0 Q13546 |
| Dna damage telomere stress induced senescence 0 38 0.0 1.0 1.0 |
| Oncogene induced senescence 0 30 0.0 1.0 1.0 |
| Formation of senescence associated heterochromatin foci sahf 0 15 0.0 1.0 1.0 |
| Cellular senescence 1 131 0.30324374420759964 0.9621170154486476 1.0 O75530 |
| Senescence associated secretory phenotype sasp 0 54 0.0 1.0 1.0 |
| Oxidative stress induced senescence 1 69 0.583392393101819 0.8207074876125077 1.0 O75530 |
| Mitotic metaphase and anaphase 9 225 1.6822268326417704 0.10205841062243774 1.0 O43237,P14635,P25787,P49720,P49721,P55735,Q8WUX9,Q92674,Q96FJ2 |
| Interaction with cumulus cells and the zona pellucida 0 1 0.0 1.0 1.0 |
| The phototransduction cascade 0 12 0.0 1.0 1.0 |
| Resolution of sister chromatid cohesion 5 120 1.744631765749778 0.17189452758232363 1.0 O43237,P14635,P55735,Q92674,Q96FJ2 |
| Visual phototransduction 0 40 0.0 1.0 1.0 |
| Loss of function of smad2 3 in cancer 0 7 0.0 1.0 1.0 |
| Glycogen synthesis 0 11 0.0 1.0 1.0 |
| Cd28 co stimulation 1 24 1.7326698096734765 0.4492542995146525 1.0 P12931 |
| Receptor type tyrosine protein phosphatases 0 11 0.0 1.0 1.0 |
| Costimulation by the cd28 family 1 39 1.04713591206933 0.6209197844592236 1.0 P12931 |
| Beta catenin independent wnt signaling 4 117 1.4149219368299877 0.32281193317441026 1.0 P25787,P49720,P49721,P62879 |
| Nuclear receptor transcription pathway 1 29 1.4225473321858864 0.5136995062503719 1.0 P11474 |
| Abc family proteins mediated transport 3 75 1.6656545209176787 0.2790882191036065 1.0 P25787,P49720,P49721 |
| Cross presentation of particulate exogenous antigens phagosomes 0 3 0.0 1.0 1.0 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0 12 0.0 1.0 1.0 |
| Olfactory signaling pathway 0 2 0.0 1.0 1.0 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 1 27 1.5322829780661107 0.48887573248844235 1.0 P62879 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 1 56 0.7222343921139102 0.7519219756551887 1.0 Q9BTY2 |
| Transcriptional regulation of white adipocyte differentiation 1 68 0.59215968351016 0.8161698151860872 1.0 Q71SY5 |
| Atf6 atf6 alpha activates chaperone genes 0 6 0.0 1.0 1.0 |
| Unfolded protein response upr 2 75 1.0906981882456916 0.5525895141700823 1.0 P43307,Q9NQT5 |
| Ire1alpha activates chaperones 1 44 0.924908938077893 0.6653399447031942 1.0 P43307 |
| Perk regulates gene expression 1 26 1.5937349397590361 0.47599457655385613 1.0 Q9NQT5 |
| Atf6 atf6 alpha activates chaperones 0 8 0.0 1.0 1.0 |
| Atf4 activates genes in response to endoplasmic reticulum stress 1 22 1.8980684643335246 0.42115518658714335 1.0 Q9NQT5 |
| Energy dependent regulation of mtor by lkb1 ampk 0 27 0.0 1.0 1.0 |
| Cd28 dependent pi3k akt signaling 0 15 0.0 1.0 1.0 |
| Recruitment of numa to mitotic centrosomes 2 90 0.9034090909090909 0.6519941826074332 1.0 O94927,Q13561 |
| Cd28 dependent vav1 pathway 0 7 0.0 1.0 1.0 |
| Alpha oxidation of phytanate 1 6 7.9847389558232935 0.1384198135311803 1.0 O43808 |
| Rap1 signalling 0 13 0.0 1.0 1.0 |
| G beta gamma signalling through pi3kgamma 1 15 2.849110728628801 0.31108300972667774 1.0 P62879 |
| Signaling by erbb4 2 36 2.351043643263757 0.22054412764311498 1.0 P12931,P16949 |
| Nitric oxide stimulates guanylate cyclase 0 11 0.0 1.0 1.0 |
| Protein folding 1 79 0.5080836165173515 0.8603774023730821 1.0 P62879 |
| Signal regulatory protein family interactions 1 9 4.988955823293173 0.20029633215213802 1.0 P12931 |
| Peroxisomal lipid metabolism 2 24 3.6378299120234603 0.11624268982638863 1.0 O43808,P09110 |
| Diseases associated with o glycosylation of proteins 1 17 2.4924698795180724 0.34450269493005076 1.0 O43505 |
| Striated muscle contraction 0 16 0.0 1.0 1.0 |
| Association of tric cct with target proteins during biosynthesis 0 36 0.0 1.0 1.0 |
| Folding of actin by cct tric 0 10 0.0 1.0 1.0 |
| Beta oxidation of very long chain fatty acids 1 9 4.988955823293173 0.20029633215213802 1.0 P09110 |
| Post chaperonin tubulin folding pathway 0 18 0.0 1.0 1.0 |
| Formation of tubulin folding intermediates by cct tric 0 21 0.0 1.0 1.0 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 0 28 0.0 1.0 1.0 |
| Pd 1 signaling 0 5 0.0 1.0 1.0 |
| Sumoylation of transcription cofactors 1 41 0.994578313253012 0.6393520558322405 1.0 P52739 |
| Beta oxidation of pristanoyl coa 0 7 0.0 1.0 1.0 |
| Glyoxylate metabolism and glycine degradation 0 22 0.0 1.0 1.0 |
| Ctla4 inhibitory signaling 1 17 2.4924698795180724 0.34450269493005076 1.0 P12931 |
| Signaling by tgf beta receptor complex in cancer 0 8 0.0 1.0 1.0 |
| Recruitment of mitotic centrosome proteins and complexes 2 82 0.9945564516129032 0.6013160240942994 1.0 O94927,Q13561 |
| Mitochondrial trna aminoacylation 0 23 0.0 1.0 1.0 |
| Defective chsy1 causes tpbs 0 4 0.0 1.0 1.0 |
| Defective chst14 causes eds musculocontractural type 0 4 0.0 1.0 1.0 |
| Defective chst3 causes sedcjd 0 4 0.0 1.0 1.0 |
| Defective b4galt7 causes eds progeroid type 0 13 0.0 1.0 1.0 |
| Diseases associated with glycosaminoglycan metabolism 0 26 0.0 1.0 1.0 |
| Grb2 sos provides linkage to mapk signaling for integrins 1 9 4.988955823293173 0.20029633215213802 1.0 P12931 |
| Integrin signaling 1 18 2.3456177651783605 0.3606019508791212 1.0 P12931 |
| Amino acid transport across the plasma membrane 0 17 0.0 1.0 1.0 |
| Apoptotic cleavage of cell adhesion proteins 0 9 0.0 1.0 1.0 |
| Metabolism of polyamines 3 48 2.6723346828609986 0.11291463467421847 1.0 P25787,P49720,P49721 |
| Notch hlh transcription pathway 0 21 0.0 1.0 1.0 |
| Hsf1 dependent transactivation 0 30 0.0 1.0 1.0 |
| Attenuation phase 0 22 0.0 1.0 1.0 |
| Cellular response to heat stress 1 93 0.43015540422559806 0.901661417560863 1.0 P55735 |
| Hsf1 activation 0 25 0.0 1.0 1.0 |
| Cross presentation of soluble exogenous antigens endosomes 3 41 3.166844236096314 0.07859592823555898 1.0 P25787,P49720,P49721 |
| Regulation of hsf1 mediated heat shock response 1 76 0.5285676037483267 0.8494956492245809 1.0 P55735 |
| Regulation by c flip 1 10 4.4341811691209285 0.2199219252501269 1.0 Q13546 |
| Defects in biotin btn metabolism 0 8 0.0 1.0 1.0 |
| Defective chst6 causes mcdc1 0 1 0.0 1.0 1.0 |
| Chemokine receptors bind chemokines 0 3 0.0 1.0 1.0 |
| Defective ext2 causes exostoses 2 0 11 0.0 1.0 1.0 |
| Transcriptional regulation by tp53 8 333 0.9786141131595677 0.5744209263923574 1.0 O00483,O43819,P13073,P14635,P42575,P62875,Q8N0Z6,Q9UQ84 |
| Trna aminoacylation 0 43 0.0 1.0 1.0 |
| Cytosolic trna aminoacylation 0 24 0.0 1.0 1.0 |
| Antigen processing cross presentation 4 77 2.199131306381557 0.1201562976350847 1.0 P25787,P49720,P49721,P60468 |
| Myoclonic epilepsy of lafora 0 5 0.0 1.0 1.0 |
| Diseases of glycosylation 3 76 1.642670955576507 0.28578996015665553 1.0 O43505,P16278,Q2TAA5 |
| Diseases associated with n glycosylation of proteins 1 18 2.3456177651783605 0.3606019508791212 1.0 Q2TAA5 |
| Negative regulation of tcf dependent signaling by wnt ligand antagonists 0 5 0.0 1.0 1.0 |
| Deactivation of the beta catenin transactivating complex 0 36 0.0 1.0 1.0 |
| Endosomal vacuolar pathway 0 10 0.0 1.0 1.0 |
| Dscam interactions 0 9 0.0 1.0 1.0 |
| Ncam signaling for neurite out growth 2 34 2.4984879032258065 0.2024630111897534 1.0 P12931,P18433 |
| L1cam interactions 3 91 1.3605999263894 0.3866675549018741 1.0 O14786,P12931,Q92796 |
| Semaphorin interactions 1 48 0.8458514910706656 0.6971115950162535 1.0 O14786 |
| Nephrin family interactions 0 17 0.0 1.0 1.0 |
| Netrin 1 signaling 1 33 1.2442269076305221 0.559801856438838 1.0 P12931 |
| Class b 2 secretin family receptors 1 25 1.6603078982597055 0.4627901258069825 1.0 P62879 |
| Class a 1 rhodopsin like receptors 2 21 4.213497453310696 0.09270379205394921 1.0 P07602,Q9NZJ7 |
| Signaling by gpcr 5 204 0.9995897856630089 0.5637909965358673 1.0 P07602,P12931,P62879,P63096,Q9NZJ7 |
| P130cas linkage to mapk signaling for integrins 1 9 4.988955823293173 0.20029633215213802 1.0 P12931 |
| Defective b4galt1 causes b4galt1 cdg cdg 2d 0 1 0.0 1.0 1.0 |
| Interleukin 6 signaling 0 8 0.0 1.0 1.0 |
|
|
