| term overlap setsize score pval |
| Biological oxidations 23 49 3.0143864816176382 0.0025749955357388 |
| Biotin transport and metabolism 6 8 -2.723061350006175 0.0064680045453753 |
| Defects in biotin btn metabolism 5 7 -2.648852570271089 0.0080765556081088 |
| Rhoc gtpase cycle 11 35 -2.6160141835114485 0.0088962862044854 |
| Activation of bad and translocation to mitochondria 5 6 -2.4969216812693547 0.0125276621863181 |
| Rhobtb gtpase cycle 14 31 -2.418935836881331 0.015565985630694 |
| Pink1 prkn mediated mitophagy 1 6 2.366887560919911 0.0179383816848517 |
| Notch3 activation and transmission of signal to the nucleus 1 1 -2.3649727101786344 0.0180313995528118 |
| Defects in vitamin and cofactor metabolism 5 11 -2.350788900278248 0.0187336586126234 |
| Pre notch processing in the endoplasmic reticulum 0 1 2.329181271136365 0.0198494646665294 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 1 1 -2.3250969357657163 0.0200667774702079 |
| Scavenging by class b receptors 0 1 2.3148712753208374 0.0206199777941034 |
| Passive transport by aquaporins 1 1 -2.299522052014089 0.0214753126320383 |
| Signaling by alk in cancer 18 32 -2.298481125833748 0.0215344209017307 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 2 10 2.2897484575947264 0.0220359025917462 |
| Tlr3 mediated ticam1 dependent programmed cell death 0 1 2.2607006003579837 0.0237778032805815 |
| Trp channels 0 1 2.2607006003579837 0.0237778032805815 |
| Trif mediated programmed cell death 0 1 2.2607006003579837 0.0237778032805815 |
| Metabolism of water soluble vitamins and cofactors 7 38 -2.256114405156099 0.0240634672088426 |
| Diseases associated with o glycosylation of proteins 0 1 2.2399430199908683 0.0250946222804391 |
| Keratan sulfate biosynthesis 0 1 2.2399430199908683 0.0250946222804391 |
| N glycan trimming and elongation in the cis golgi 0 1 2.207960766569514 0.0272470082130511 |
| Activated ntrk3 signals through pi3k 0 1 2.1967536231488864 0.02803804687981 |
| Androgen biosynthesis 0 1 2.1871420779526094 0.0287321537094953 |
| Phase ii conjugation of compounds 12 32 2.177082700021935 0.0294743975936671 |
| Defective intrinsic pathway for apoptosis 9 15 -2.1749899287306658 0.0296308711069626 |
| Activation of ampk downstream of nmdars 4 7 2.164426769423813 0.0304316111980889 |
| Notch4 activation and transmission of signal to the nucleus 1 1 -2.1436045046511216 0.0320645895418154 |
| Mitophagy 4 10 2.1385283545866 0.0324738853570956 |
| Regulation of foxo transcriptional activity by acetylation 1 1 -2.1339132491200474 0.0328498827284602 |
| Chrebp activates metabolic gene expression 2 5 -2.128044480533667 0.0333333958136146 |
| Dopamine clearance from the synaptic cleft 0 1 2.12294080214821 0.0337588127827328 |
| Digestion and absorption 1 1 -2.112897749312207 0.0346095205589576 |
| Digestion 1 1 -2.112897749312207 0.0346095205589576 |
| Diseases of metabolism 9 44 -2.111982922079322 0.0346879141293023 |
| Phase i functionalization of compounds 7 16 2.1114508515946806 0.0347335781435624 |
| Acyl chain remodelling of pc 0 1 2.110075411703204 0.0348518608174053 |
| Tight junction interactions 0 1 2.108466666777016 0.0349906431101176 |
| Apoptotic execution phase 11 33 -2.099702947455604 0.035754980155495 |
| Mitochondrial protein import 11 35 2.0838718811365884 0.0371718226996495 |
| Synthesis of dolichyl phosphate 0 1 2.0633715884796024 0.0390773371830563 |
| Organic anion transporters 0 1 2.061759295466854 0.0392306581542407 |
| Sulfide oxidation to sulfate 0 1 2.061759295466854 0.0392306581542407 |
| Synthesis of wybutosine at g37 of trna phe 0 1 2.056921708157568 0.039693757472758 |
| Assembly of active lpl and lipc lipase complexes 0 1 2.040788831186188 0.0412718211980267 |
| Regulation of runx1 expression and activity 0 5 2.0037509863057514 0.0450967415914778 |
| Respiratory electron transport 16 46 2.0018097259082186 0.0453051995271085 |
| Post translational modification synthesis of gpi anchored proteins 2 5 1.993955853785794 0.0461568791853563 |
| Iron uptake and transport 3 17 1.968945809699443 0.0489593142767419 |
| Pi3k events in erbb2 signaling 1 1 -1.952111253004504 0.05092499750681 |
| Activated ntrk2 signals through pi3k 1 1 -1.952111253004504 0.05092499750681 |
| Interleukin receptor shc signaling 1 1 -1.952111253004504 0.05092499750681 |
| Metabolism of vitamins and cofactors 8 46 -1.9351618601822584 0.0529704363824059 |
| Regulation of localization of foxo transcription factors 3 4 -1.9284684284286389 0.0537968875734373 |
| Metabolism of steroid hormones 1 5 1.9072495075957725 0.0564882852840105 |
| Transport of nucleotide sugars 0 1 1.904851641439929 0.0567993588407209 |
| Runx3 regulates bcl2l11 bim transcription 1 1 -1.9047866342950357 0.0568078119797839 |
| Foxo mediated transcription of cell cycle genes 1 1 -1.9047866342950357 0.0568078119797839 |
| Loss of function of smad2 3 in cancer 1 1 -1.9047866342950357 0.0568078119797839 |
| Pexophagy 1 1 -1.8966180596366375 0.0578783653021333 |
| Foxo mediated transcription 6 10 -1.8713718547189824 0.0612935572350894 |
| Bbsome mediated cargo targeting to cilium 2 8 -1.8642372680089725 0.0622883919322716 |
| Arachidonic acid metabolism 0 4 1.8552416217238192 0.0635617305066644 |
| Synthesis of very long chain fatty acyl coas 2 7 1.8477364555911533 0.0646404774358766 |
| Downregulation of smad2 3 smad4 transcriptional activity 4 7 -1.847368375869896 0.0646937692770137 |
| Fasl cd95l signaling 1 1 -1.8459170774137812 0.064904246638429 |
| Integration of energy metabolism 4 25 -1.8396943403843844 0.0658131249353854 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 1 1 -1.834455882613745 0.0665863508752633 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 1 1 -1.834455882613745 0.0665863508752633 |
| Interleukin 10 signaling 1 1 -1.834455882613745 0.0665863508752633 |
| Ncam1 interactions 0 1 1.8220097149803385 0.0684535115811844 |
| E2f enabled inhibition of pre replication complex formation 1 5 1.8201803196868096 0.0687315491348843 |
| Assembly of the orc complex at the origin of replication 2 7 1.8195685177661596 0.0688247396366861 |
| Apoptotic factor mediated response 2 6 -1.8135997137544728 0.0697393745556436 |
| Tnfr1 mediated ceramide production 0 1 1.795982811977273 0.072497250656131 |
| Synthesis of substrates in n glycan biosythesis 9 17 1.7915259423112135 0.073208935394347 |
| Amino acid transport across the plasma membrane 1 6 -1.7841425773825763 0.0744005002558432 |
| Interleukin 37 signaling 3 4 -1.773196838841051 0.076196095697542 |
| Mrna decay by 5 to 3 exoribonuclease 3 9 -1.7696684083951622 0.0767823955806272 |
| Transport of connexons to the plasma membrane 3 4 1.7692557062749683 0.0768512116132722 |
| Gap junction assembly 3 4 1.7692557062749683 0.0768512116132722 |
| Cdc42 gtpase cycle 14 33 -1.7639374247606685 0.0777425150621962 |
| Gaba b receptor activation 4 5 1.7603548896408063 0.0783476528595357 |
| Gaba receptor activation 4 5 1.7603548896408063 0.0783476528595357 |
| Adp signalling through p2y purinoceptor 12 4 5 1.7603548896408063 0.0783476528595357 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 20 54 1.754377046530872 0.0793659217332389 |
| Selective autophagy 9 31 1.754123293008798 0.0794093832221773 |
| Sulfur amino acid metabolism 2 9 1.7536750801027563 0.0794861979079337 |
| Ticam1 dependent activation of irf3 irf7 1 1 -1.752472359969494 0.0796926185599056 |
| Pre notch expression and processing 2 8 1.7284978562917477 0.0838990050268095 |
| Cation coupled chloride cotransporters 1 1 -1.716343380330852 0.0860992129225803 |
| Cholesterol biosynthesis 5 15 1.713359595104583 0.0866464048088286 |
| Ca dependent events 3 10 -1.7095216850647494 0.0873543583954683 |
| Thrombin signalling through proteinase activated receptors pars 3 6 1.7085886317748316 0.0875271759198941 |
| Synthesis of pg 2 4 1.700875747386799 0.08896632162976 |
| Norepinephrine neurotransmitter release cycle 0 1 1.6950093693986985 0.090073643407825 |
| Serotonin neurotransmitter release cycle 0 1 1.6950093693986985 0.090073643407825 |
| Acetylcholine neurotransmitter release cycle 0 1 1.6950093693986985 0.090073643407825 |
| Alk mutants bind tkis 6 7 -1.6931998284181005 0.0904174372551442 |
| Sphingolipid de novo biosynthesis 5 8 1.691825867050355 0.0906791800388353 |
| Activation of the phototransduction cascade 0 1 1.69174989513786 0.0906936706253112 |
| Sensory perception of taste 0 1 1.69174989513786 0.0906936706253112 |
| Olfactory signaling pathway 0 1 1.69174989513786 0.0906936706253112 |
| Diseases of programmed cell death 5 28 -1.6799572626623465 0.0929656311963382 |
| Hur elavl1 binds and stabilizes mrna 3 5 -1.6748649934180604 0.0939607233951476 |
| Formation of tubulin folding intermediates by cct tric 3 12 1.668362441871037 0.0952437992970511 |
| Intrinsic pathway for apoptosis 8 17 -1.6595848286368025 0.096998002477799 |
| Ion channel transport 4 22 1.6565153111847926 0.097617506976789 |
| Smooth muscle contraction 9 10 -1.6552140625636915 0.0978810836748562 |
| Ketone body metabolism 2 4 1.6461622320739662 0.0997303627187435 |
| Metabolism of folate and pterines 0 8 1.645108349745081 0.0999474690092248 |
| Activation of rac1 3 6 -1.6350671189322428 0.1020349781492457 |
| Long term potentiation 1 6 1.6345954706266308 0.1021338777868428 |
| Receptor type tyrosine protein phosphatases 1 1 -1.6127530065491664 0.1067981794515511 |
| Rhob gtpase cycle 9 25 -1.5999919454808382 0.1096003702386063 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 5 9 -1.585097130806415 0.1129442673902385 |
| Class a 1 rhodopsin like receptors 2 6 1.5841053933745035 0.1131697372557782 |
| Peptide ligand binding receptors 2 6 1.5841053933745035 0.1131697372557782 |
| Met receptor activation 1 1 -1.5831343659192811 0.1133908422085223 |
| Chaperone mediated autophagy 5 6 -1.579578765892121 0.114203365236233 |
| Cohesin loading onto chromatin 3 8 -1.5686669973825793 0.1167255523879702 |
| Mrna editing c to u conversion 0 1 1.5662363184000658 0.117293303176625 |
| Mitotic telophase cytokinesis 4 11 -1.557570451256901 0.1193351078331492 |
| Trafficking of myristoylated proteins to the cilium 1 1 -1.5568041075600851 0.1195170016931439 |
| Thromboxane signalling through tp receptor 2 4 1.55105238565876 0.120889130449552 |
| Ethanol oxidation 1 4 1.5286688639527857 0.1263465548054498 |
| Activation of ras in b cells 0 1 1.5238757701104997 0.1275397472316339 |
| Ikba variant leads to eda id 1 1 -1.5173104193945055 0.1291883287833548 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0 4 1.5137775737730894 0.1300822623563025 |
| Phosphate bond hydrolysis by nudt proteins 2 4 -1.5073106383131778 0.1317310520094734 |
| Trna modification in the mitochondrion 2 8 1.5061689734916774 0.1320238020499726 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 8 22 1.503688213867726 0.1326616653696315 |
| Adrenaline noradrenaline inhibits insulin secretion 3 4 1.5025531856717556 0.1329543031406443 |
| Pyruvate metabolism and citric acid tca cycle 10 33 1.4973490249604309 0.1343024646792172 |
| Generation of second messenger molecules 4 5 -1.4918932586610218 0.1357271302297864 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 4 9 -1.491636667385949 0.1357944202372296 |
| Tp53 regulates transcription of caspase activators and caspases 1 4 1.4869276084676382 0.137033931566409 |
| Wnt ligand biogenesis and trafficking 3 5 1.4813906972861084 0.1385024922362818 |
| Apoptotic cleavage of cellular proteins 8 21 -1.4784083946311508 0.1392984998409909 |
| Mitochondrial calcium ion transport 4 15 1.4736987478966794 0.1405627201378596 |
| Assembly of the hiv virion 0 1 1.4734115869371625 0.1406400878183582 |
| Molybdenum cofactor biosynthesis 1 4 -1.4715306530840846 0.1411476640363025 |
| A tetrasaccharide linker sequence is required for gag synthesis 1 1 -1.464670841843157 0.1430107438565346 |
| Protein localization 21 67 1.4577500186069965 0.1449094594979656 |
| Rhobtb1 gtpase cycle 9 21 -1.4565861797381523 0.1452306448785398 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 3 7 1.4565165117359888 0.1452498884849133 |
| Lysine catabolism 3 6 1.451621300530988 0.1466069327365251 |
| Visual phototransduction 3 7 1.4511781028116113 0.1467302726538197 |
| Sumoylation of dna damage response and repair proteins 13 46 -1.4498057534397983 0.1471126946638963 |
| Advanced glycosylation endproduct receptor signaling 1 6 1.438880211148058 0.150184465151713 |
| Rhobtb2 gtpase cycle 10 21 -1.4331212614639215 0.1518231863316068 |
| Elastic fibre formation 1 1 -1.4301487568818718 0.1526743290354135 |
| Fibronectin matrix formation 1 1 -1.4301487568818718 0.1526743290354135 |
| Molecules associated with elastic fibres 1 1 -1.4301487568818718 0.1526743290354135 |
| Laminin interactions 1 1 -1.4301487568818718 0.1526743290354135 |
| Other semaphorin interactions 1 1 -1.4301487568818718 0.1526743290354135 |
| Cytosolic sulfonation of small molecules 2 5 1.4286445618580332 0.1531064192977447 |
| Metabolism of porphyrins 1 9 1.4273028975793534 0.1534926057772083 |
| Activation of bh3 only proteins 5 9 -1.425877125443586 0.1539038132964958 |
| Heme degradation 1 4 1.425691621681079 0.1539573760148935 |
| Rho gtpases activate pkns 9 19 -1.4230710111305085 0.1547155709164664 |
| Citric acid cycle tca cycle 6 19 1.4110870609830797 0.1582189447247235 |
| Formation of senescence associated heterochromatin foci sahf 2 9 -1.4074455705657791 0.1592953063313438 |
| Phenylalanine and tyrosine metabolism 3 5 -1.4024045075840754 0.1607944880894507 |
| Pi3k akt activation 0 1 1.397042999383202 0.1624006409942917 |
| Ampk inhibits chrebp transcriptional activation activity 0 1 1.3954205602615286 0.1628890548378567 |
| Beta oxidation of very long chain fatty acids 2 5 1.3930416271904449 0.1636072031246302 |
| Myogenesis 4 6 -1.3923496058638378 0.1638165567689076 |
| Wax and plasmalogen biosynthesis 3 4 1.3907074811897169 0.1643141481021601 |
| Gap junction degradation 5 6 -1.3870030332217045 0.165440837917669 |
| Signaling by notch3 2 5 -1.382315972644329 0.166874703728354 |
| Met activates rap1 and rac1 2 5 -1.379077590525641 0.1678708323426161 |
| Pka activation in glucagon signalling 1 4 -1.3637357964408765 0.1726507335059781 |
| Pka mediated phosphorylation of creb 1 4 -1.3637357964408765 0.1726507335059781 |
| Creb1 phosphorylation through the activation of adenylate cyclase 1 4 -1.3637357964408765 0.1726507335059781 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 1 1 -1.3628337995278277 0.172934896232269 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 1 3 1.3594520919322732 0.1740033737793063 |
| Ion transport by p type atpases 2 10 1.3588638688112562 0.1741897299586399 |
| Tnfr1 induced nfkappab signaling pathway 2 6 1.3570738700423588 0.1747577400845932 |
| Runx1 regulates expression of components of tight junctions 2 3 -1.3516289977026106 0.1764940290990941 |
| Dag and ip3 signaling 3 11 -1.3509200139759678 0.1767210563011865 |
| Signal amplification 6 9 1.3410616411852865 0.1799004400995425 |
| Sodium calcium exchangers 1 1 -1.339882948594458 0.1802834025087687 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 4 11 1.3394900181819664 0.1804112018317343 |
| Ras processing 2 5 1.337193870584107 0.1811593621477722 |
| Intraflagellar transport 5 11 1.3348540500308004 0.18192411929892 |
| Transport of vitamins nucleosides and related molecules 3 7 1.3312644200158334 0.1831020211220921 |
| Cd28 dependent vav1 pathway 2 5 -1.3199391414627692 0.1868553378914423 |
| Rhod gtpase cycle 8 26 -1.3190781043667617 0.1871430023583746 |
| Assembly and cell surface presentation of nmda receptors 4 11 1.316026920277835 0.1881650073363889 |
| Recruitment of numa to mitotic centrosomes 9 32 -1.314979990203511 0.188516627471857 |
| Aquaporin mediated transport 2 7 -1.314043097660002 0.1888317012944025 |
| Lysosome vesicle biogenesis 8 13 -1.3113324494195877 0.1897454698900049 |
| Neurotransmitter receptors and postsynaptic signal transmission 13 39 1.3068036227165498 0.1912794145025078 |
| Rhoh gtpase cycle 7 23 -1.3017354274040926 0.1930068444091826 |
| Synthesis of prostaglandins pg and thromboxanes tx 0 3 1.300891764993132 0.1932955052846092 |
| Keratan sulfate keratin metabolism 2 5 1.3001986139925297 0.1935329055584755 |
| Ikk complex recruitment mediated by rip1 1 5 1.287825483943861 0.1978067191785204 |
| Cristae formation 12 18 1.2834006321306706 0.1993517525376233 |
| Diseases associated with glycosylation precursor biosynthesis 2 8 1.282014046772858 0.1998377187338471 |
| Nef mediated downregulation of mhc class i complex cell surface expression 4 5 -1.280281938057689 0.2004459976339239 |
| Activation of kainate receptors upon glutamate binding 2 5 1.2750857872594954 0.2022788793798122 |
| Defects in cobalamin b12 metabolism 0 4 1.2713945328482676 0.203588326623167 |
| Cobalamin cbl vitamin b12 transport and metabolism 0 4 1.2713945328482676 0.203588326623167 |
| Processing of smdt1 6 10 1.2689805854525769 0.2044479885371213 |
| Degradation of the extracellular matrix 1 9 -1.2676677337881617 0.2049166321055557 |
| Mrna decay by 3 to 5 exoribonuclease 3 16 1.2673730168965065 0.2050219433190965 |
| Reproduction 7 26 -1.2637983106249906 0.2063024277174103 |
| Meiosis 7 26 -1.2637983106249906 0.2063024277174103 |
| Regulation of fzd by ubiquitination 1 1 -1.26301167965605 0.2065849823161283 |
| Downregulation of erbb2 erbb3 signaling 1 1 -1.26301167965605 0.2065849823161283 |
| Met receptor recycling 3 5 -1.2630088756008595 0.2065859900234967 |
| Cd28 dependent pi3k akt signaling 1 1 -1.2613796337742875 0.207172102431195 |
| Recruitment of mitotic centrosome proteins and complexes 11 30 -1.2566178028406434 0.2088920650511265 |
| Collagen biosynthesis and modifying enzymes 7 11 1.2554248272621735 0.2093245812851039 |
| The canonical retinoid cycle in rods twilight vision 0 1 1.2532217573825202 0.2101250139151007 |
| Class i peroxisomal membrane protein import 2 7 1.2479246630585787 0.2120586477701276 |
| Pregnenolone biosynthesis 0 3 1.2441785098163145 0.2134338711883496 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 3 12 1.2407259889289994 0.2147069901659644 |
| Autophagy 14 48 1.230441235326351 0.2185319199236537 |
| Rac1 gtpase cycle 17 47 -1.2255620689871352 0.2203635191795379 |
| Phospholipase c mediated cascade fgfr2 1 1 -1.222262659988179 0.2216083149746324 |
| Phospholipase c mediated cascade fgfr4 1 1 -1.222262659988179 0.2216083149746324 |
| Role of second messengers in netrin 1 signaling 1 1 -1.222262659988179 0.2216083149746324 |
| Egfr interacts with phospholipase c gamma 1 1 -1.222262659988179 0.2216083149746324 |
| Receptor mediated mitophagy 2 4 1.2190789840013 0.2228142156381631 |
| Carboxyterminal post translational modifications of tubulin 3 6 1.2185703502283467 0.2230073082875878 |
| Signaling by hippo 3 6 -1.2182543436339808 0.223127334170134 |
| Carnitine metabolism 3 6 -1.2154781250050264 0.2241837869709226 |
| Complex i biogenesis 14 24 1.2111662601662958 0.2258316908917923 |
| Role of abl in robo slit signaling 2 4 -1.2101946169737654 0.2262042231952317 |
| Peroxisomal lipid metabolism 4 9 1.2084316436114284 0.2268812742319768 |
| Met activates ras signaling 3 5 -1.2080757459045426 0.227018128073164 |
| Nicotinate metabolism 2 4 1.2080614108078036 0.2270236416008413 |
| Rora activates gene expression 2 3 -1.2064325841499246 0.2276507386012485 |
| Signaling by pdgfr in disease 3 6 -1.2026816819902078 0.2290995251675824 |
| Reduction of cytosolic ca levels 0 4 1.2013779411101209 0.2296046289187781 |
| Platelet calcium homeostasis 0 4 1.2013779411101209 0.2296046289187781 |
| Glycogen storage diseases 2 3 -1.2002171991755743 0.2300549973340087 |
| Methionine salvage pathway 0 3 1.1964031244877926 0.2315392826372746 |
| Post chaperonin tubulin folding pathway 5 9 1.189678524864663 0.2341727691235533 |
| Phenylalanine metabolism 3 3 -1.189200820314851 0.2343606518041576 |
| Collagen degradation 0 1 1.1842947991300348 0.2362963868808321 |
| Gpvi mediated activation cascade 4 6 1.179528498221419 0.2381877957099454 |
| G2 phase 0 1 1.1763106010198785 0.2394707810831216 |
| Establishment of sister chromatid cohesion 5 7 -1.1676247809989653 0.2429581497924835 |
| Activated tak1 mediates p38 mapk activation 2 4 -1.165543037172725 0.2437992500822774 |
| Rna polymerase iii transcription termination 4 8 -1.1603405295279186 0.2459101893474606 |
| Lgi adam interactions 1 1 -1.1508507031669424 0.2497936613791902 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 1 11 1.150188522178481 0.2500662325831035 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 3 5 1.148623834748817 0.2507111245155358 |
| Inflammasomes 0 3 1.1447663405598083 0.2523059619824401 |
| Purinergic signaling in leishmaniasis infection 0 3 1.1447663405598083 0.2523059619824401 |
| The nlrp3 inflammasome 0 3 1.1447663405598083 0.2523059619824401 |
| Rhof gtpase cycle 6 17 -1.1390214941574257 0.2546941892964045 |
| Cdc6 association with the orc origin complex 0 3 1.1389305398549152 0.2547321265158635 |
| Metalloprotease dubs 2 6 1.1385476723108627 0.2548918644186826 |
| Glutamate neurotransmitter release cycle 3 4 -1.137292663727299 0.2554159605914778 |
| The phototransduction cascade 1 4 1.136399155145713 0.2557895492263058 |
| Heme biosynthesis 2 5 1.1344945835765003 0.256587144472679 |
| Aurka activation by tpx2 8 29 -1.1332493624534294 0.2571095500437261 |
| Scavenging by class f receptors 4 4 -1.1304934949860954 0.258268337930911 |
| Sialic acid metabolism 4 5 1.127338771787222 0.2595992755905567 |
| Trans golgi network vesicle budding 11 34 -1.1214235199156992 0.2621076292625393 |
| Meiotic synapsis 4 16 -1.120331086925448 0.2625726994264687 |
| Notch2 intracellular domain regulates transcription 1 1 -1.120157541845667 0.2626466333949613 |
| Signaling by notch2 1 1 -1.120157541845667 0.2626466333949613 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 0 7 1.117320364957621 0.2638573710584173 |
| Resolution of d loop structures 0 7 1.117320364957621 0.2638573710584173 |
| Apoptotic cleavage of cell adhesion proteins 2 7 -1.1096891845894106 0.2671329850242299 |
| Nectin necl trans heterodimerization 0 1 1.1032068495850134 0.2699373474622819 |
| Attachment of gpi anchor to upar 1 3 1.101837538188097 0.270532307555255 |
| Rna polymerase iii transcription 7 13 -1.1011472100738924 0.2708325928300641 |
| Ca2 pathway 4 7 1.1002971283842056 0.271202682918104 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 1 4 1.1001770340307 0.2712549949051741 |
| Signaling by cytosolic fgfr1 fusion mutants 4 7 -1.0954959633972332 0.2732994129971342 |
| Glycosaminoglycan metabolism 3 11 1.0950478204338523 0.2734956868095817 |
| Signaling by csf3 g csf 4 8 -1.092549918736253 0.2745914616976685 |
| Regulation of plk1 activity at g2 m transition 8 35 -1.089251931934995 0.2760428035459759 |
| Anchoring of the basal body to the plasma membrane 8 30 -1.0890462697271932 0.2761334820946604 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 4 5 -1.087549107238733 0.2767942083761223 |
| Synthesis of udp n acetyl glucosamine 1 5 1.0869034827817456 0.2770794669771965 |
| Bicarbonate transporters 0 1 1.082674221201028 0.2789530502069492 |
| Nef mediated cd4 down regulation 2 6 1.0822858598523344 0.2791255271125017 |
| Nef mediated cd8 down regulation 2 6 1.0822858598523344 0.2791255271125017 |
| Sumoylation of dna replication proteins 11 35 -1.0820130324508352 0.2792467370790239 |
| Collagen formation 8 13 1.0792915758767263 0.2804577670825088 |
| Tp53 regulates metabolic genes 13 35 -1.0778801766076551 0.2810872330538583 |
| Interleukin 3 interleukin 5 and gm csf signaling 2 8 -1.077408116158487 0.2812979798181354 |
| Regulation of tnfr1 signaling 2 6 1.074813558763006 0.2824582087793383 |
| Dscam interactions 2 3 -1.0732985964387325 0.2831371647508325 |
| O linked glycosylation 2 3 1.0700713314870096 0.28458720221748 |
| O linked glycosylation of mucins 2 3 1.0700713314870096 0.28458720221748 |
| Ctla4 inhibitory signaling 4 8 1.0635839335542394 0.2875172238504531 |
| Inla mediated entry of listeria monocytogenes into host cells 0 3 1.060586864721435 0.28887769456438 |
| Striated muscle contraction 3 4 -1.0533938457732852 0.2921605235939435 |
| Protein ubiquitination 15 26 -1.0533506200236007 0.292180326891994 |
| Mucopolysaccharidoses 1 3 1.050848202456519 0.2933283132116182 |
| Tnf signaling 2 7 1.0385387529232326 0.2990193031707273 |
| G alpha 12 13 signalling events 5 10 1.0327998636670708 0.3016975675663349 |
| Rhog gtpase cycle 9 34 -1.0293319207320877 0.3033237282797727 |
| Sphingolipid metabolism 11 24 1.0280807256994562 0.3039118563326211 |
| Regulation of cholesterol biosynthesis by srebp srebf 9 23 -1.0260478075353112 0.3048690499729711 |
| Dna damage telomere stress induced senescence 4 16 -1.0255181031368286 0.3051187879869941 |
| Uptake and actions of bacterial toxins 5 7 -1.0176958226762716 0.308822533085165 |
| Mitotic prophase 19 60 -1.0169119846198311 0.3091953015429967 |
| Cellular senescence 9 40 -1.0154331176474245 0.3098994131229644 |
| Synthesis of diphthamide eef2 1 4 1.0134651530093808 0.3108380326775706 |
| Signaling by mras complex mutants 3 5 1.0122442979591364 0.3114212605982944 |
| Aflatoxin activation and detoxification 1 3 1.0073930887801588 0.313745911223676 |
| G beta gamma signalling through pi3kgamma 2 3 1.007065712450823 0.3139031968578136 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 2 3 1.007065712450821 0.3139031968578145 |
| Rhoa gtpase cycle 13 47 -1.0030801506451088 0.3158221909484653 |
| Insulin receptor recycling 2 9 1.0025208388600302 0.3160921070846476 |
| Rho gtpases activate paks 5 12 -1.0021102000919069 0.3162903720540662 |
| Rna polymerase iii transcription initiation from type 3 promoter 4 7 -1.0011764805704215 0.3167414950640821 |
| Rna polymerase iii chain elongation 4 7 -1.0011764805704215 0.3167414950640821 |
| Neurotransmitter release cycle 2 9 -0.9983699340312872 0.3181000072936129 |
| Abacavir transport and metabolism 0 1 0.9980957868295643 0.3182329129359356 |
| Abacavir metabolism 0 1 0.9980957868295643 0.3182329129359356 |
| Mecp2 regulates transcription factors 0 1 0.993434079453586 0.3204984605669141 |
| G alpha s signalling events 4 9 0.9915576299719376 0.3214133665698617 |
| Interleukin 2 family signaling 2 3 -0.9840411897542471 0.3250952609751676 |
| Displacement of dna glycosylase by apex1 1 4 0.9816677117228332 0.3262635772218423 |
| Repression of wnt target genes 1 4 0.9792254660304172 0.3274685884232626 |
| Estrogen biosynthesis 0 1 0.9779259182419426 0.3281109652439837 |
| Regulation of hsf1 mediated heat shock response 18 55 -0.9779143812008492 0.3281166717536024 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 3 5 -0.9773158756316116 0.32841279590812 |
| Complement cascade 1 2 -0.9689246071050436 0.3325828069918564 |
| Calnexin calreticulin cycle 4 6 -0.9656873673765364 0.3342006426036616 |
| Loss of function of mecp2 in rett syndrome 1 5 -0.9649990491152256 0.3345452880549708 |
| Nuclear envelope breakdown 11 42 -0.962240797255672 0.3359286601163589 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 0 2 0.9594627785434732 0.3373256621327953 |
| Processive synthesis on the c strand of the telomere 4 13 -0.9568600420447724 0.3386379018317131 |
| Fgfr1 mutant receptor activation 4 8 -0.9556662995662324 0.3392408538412774 |
| Rna polymerase iii transcription initiation from type 1 promoter 6 12 -0.9524537099997086 0.3408669313736112 |
| Transferrin endocytosis and recycling 2 10 0.9510694211111403 0.3415691364197646 |
| Traf6 mediated irf7 activation 3 4 -0.9489365819447636 0.3426528675219424 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 3 4 0.9416410887162734 0.3463764257043347 |
| Irf3 mediated induction of type i ifn 3 6 -0.9379326044887998 0.3482790462129919 |
| Sting mediated induction of host immune responses 3 6 -0.9379326044887998 0.3482790462129919 |
| Rap1 signalling 1 3 -0.9367457285644866 0.3488893678817559 |
| Regulation of innate immune responses to cytosolic dna 2 4 -0.9345952305670796 0.349996937899319 |
| The citric acid tca cycle and respiratory electron transport 33 85 0.9296298024590868 0.352562791368602 |
| Degradation of cysteine and homocysteine 1 4 0.9291252635611276 0.3528241731977799 |
| Mitochondrial biogenesis 13 36 0.9281177425630336 0.3533464970640403 |
| Vitamin c ascorbate metabolism 1 2 0.925004129637416 0.3549637593462127 |
| Ovarian tumor domain proteases 4 9 0.9188884248962906 0.3581539349226581 |
| Constitutive signaling by akt1 e17k in cancer 3 5 -0.9177700080016936 0.3587392871954473 |
| Met promotes cell motility 4 8 -0.9174703781969604 0.3588962082694866 |
| Formation of atp by chemiosmotic coupling 5 8 0.91674701821231 0.3592752216328732 |
| Synthesis of ketone bodies 1 3 0.9130567773239032 0.361212681078924 |
| Regulation of tp53 activity through methylation 0 3 0.9080471286761708 0.3638533224243807 |
| Adp signalling through p2y purinoceptor 1 2 4 0.9030482269533896 0.366500299848675 |
| Methylation 1 9 0.9023401962374136 0.3668761790055956 |
| Antimicrobial peptides 1 2 -0.8981483088346344 0.3691064871072109 |
| Inactivation of csf3 g csf signaling 3 6 -0.8939734053734794 0.3713361205786345 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 2 5 -0.8939232731503265 0.3713629446805546 |
| Nephrin family interactions 5 9 -0.8929529567496988 0.3718823658268566 |
| Synthesis of pi 0 1 0.8890067955446989 0.3739994276676992 |
| Choline catabolism 0 1 0.8859747703614762 0.3756311227375912 |
| Attenuation phase 7 11 -0.8824009842365784 0.3775600036624182 |
| Neurotransmitter clearance 1 2 0.8801280619972545 0.3787899387001205 |
| G alpha z signalling events 4 7 0.8799737301663463 0.3788735408208812 |
| Met activates ptpn11 2 3 -0.8782390021255019 0.3798140303813255 |
| Cytosolic sensors of pathogen associated dna 10 20 -0.875724076819537 0.3811800530827414 |
| Trna processing in the mitochondrion 1 4 0.8745755580381054 0.3818048917025072 |
| Rhou gtpase cycle 10 15 -0.8696022849658863 0.3845177886446052 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 4 7 0.8694105955923992 0.3846225897309394 |
| Tnfr1 induced proapoptotic signaling 1 3 0.8666431180328695 0.386137580784351 |
| Hs gag degradation 1 2 0.8649414391988172 0.3870709315403551 |
| Suppression of apoptosis 0 3 0.8617910459755082 0.3888025130970192 |
| Circadian clock 4 13 -0.8616556175520503 0.3888770555168834 |
| Activation of gene expression by srebf srebp 2 16 -0.858549153570524 0.390589300871051 |
| Integrin signaling 3 6 -0.8568854252225407 0.3915082084021462 |
| Platelet aggregation plug formation 3 6 -0.8568854252225407 0.3915082084021462 |
| Runx3 regulates p14 arf 2 3 -0.8555726609510164 0.392234197403464 |
| Crmps in sema3a signaling 4 7 0.8547988415996878 0.3926625196206341 |
| Diseases of mismatch repair mmr 2 3 -0.8546704234388187 0.3927336286854233 |
| Copi independent golgi to er retrograde traffic 7 26 0.85106049032436 0.3947357514497951 |
| Adenylate cyclase inhibitory pathway 2 3 0.8491064643257229 0.3958220537054289 |
| Glycogen metabolism 3 10 -0.8480510952447702 0.3964095156602147 |
| Interactions of rev with host cellular proteins 9 34 -0.8452142993828684 0.3979911999539167 |
| Heme signaling 0 7 0.8402419289212929 0.4007727537528596 |
| Interleukin 4 and interleukin 13 signaling 0 12 0.834897331156967 0.4037755175689936 |
| Vitamin b2 riboflavin metabolism 0 1 0.8333272333114579 0.4046602012732416 |
| Traf6 mediated nf kb activation 4 5 -0.8292854635100808 0.4069428944878166 |
| Synthesis of pc 2 3 0.823126674608742 0.4104359611940569 |
| Condensation of prophase chromosomes 5 10 -0.8211153770409285 0.411580551969871 |
| Downregulation of tgf beta receptor signaling 2 7 0.8171338285811401 0.4138519526398374 |
| Processing of dna double strand break ends 10 27 0.8165513956080135 0.4141848408829589 |
| Signaling by erbb2 ecd mutants 3 6 -0.8161597618558524 0.4144087673055012 |
| Signaling by erbb2 in cancer 3 6 -0.8161597618558524 0.4144087673055012 |
| Constitutive signaling by egfrviii 3 6 -0.8161597618558516 0.4144087673055017 |
| Constitutive signaling by ligand responsive egfr cancer variants 3 6 -0.8161597618558516 0.4144087673055017 |
| Signaling by egfr in cancer 3 6 -0.8161597618558516 0.4144087673055017 |
| Rnd2 gtpase cycle 7 15 -0.810692365461328 0.417542358738616 |
| Glutathione conjugation 6 15 0.8105689210641289 0.4176132706524673 |
| Glycerophospholipid biosynthesis 6 25 0.8099796102672405 0.4179518945900007 |
| Synaptic adhesion like molecules 2 6 0.8066267941144863 0.4198815319462814 |
| Rab geranylgeranylation 15 21 0.804698384952531 0.4209937517967019 |
| Rhov gtpase cycle 9 17 -0.7982600541035829 0.4247195938526507 |
| Leishmania infection 5 42 0.7911562207284993 0.4288528351260758 |
| Propionyl coa catabolism 1 3 -0.7876107111609775 0.4309244474697247 |
| Prc2 methylates histones and dna 1 8 0.7869009673934358 0.4313398411821976 |
| Synthesis of pips at the early endosome membrane 0 4 0.784498580336363 0.4327476146256896 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 1 0.7844639093719957 0.4327679508920126 |
| Erythropoietin activates stat5 0 1 0.7844639093719957 0.4327679508920126 |
| Cd22 mediated bcr regulation 0 1 0.7844639093719957 0.4327679508920126 |
| Dectin 2 family 0 1 0.7844639093719957 0.4327679508920126 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 2 4 -0.7841703654005829 0.432940151376489 |
| Synthesis of pyrophosphates in the cytosol 0 3 0.7831612395271749 0.4335324330663797 |
| Vasopressin regulates renal water homeostasis via aquaporins 1 6 -0.7805018373056916 0.4350955465019415 |
| Glucagon signaling in metabolic regulation 1 6 -0.7805018373056916 0.4350955465019415 |
| Gpcr ligand binding 4 10 0.7795643017156316 0.4356473751390748 |
| Stimuli sensing channels 0 4 0.7783075812126969 0.4363877072265656 |
| Sumoylation of transcription factors 2 6 -0.7782382752470157 0.4364285563457641 |
| Effects of pip2 hydrolysis 2 3 -0.777472621565656 0.4368799812539885 |
| Hsf1 dependent transactivation 7 16 -0.7758902720144822 0.4378137769283399 |
| Purine catabolism 2 9 -0.7704798909039258 0.4410152790339641 |
| Ras activation upon ca2 influx through nmda receptor 1 6 0.7702853821332022 0.4411306255982585 |
| Signal regulatory protein family interactions 2 5 -0.7690727134553459 0.4418501456773662 |
| Type i hemidesmosome assembly 1 1 -0.7690575694233025 0.4418591354232477 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 1 1 -0.7675522716470883 0.4427532271734555 |
| Prolonged erk activation events 1 5 -0.7641485943112843 0.4447786964625746 |
| Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0 1 0.7639830179153131 0.4448773627245681 |
| Maturation of sars cov 2 spike protein 1 9 0.7637220190044318 0.44503291619684 |
| Metabolism of steroids 5 39 0.7627051082958143 0.4456392834015283 |
| Diseases of glycosylation 4 19 0.7612233397536399 0.4465236798948404 |
| Glucuronidation 1 3 0.7607183438288257 0.4468253158040529 |
| Transcriptional regulation by mecp2 5 16 -0.7598046860076081 0.4473713414654123 |
| Sema4d in semaphorin signaling 5 11 -0.7583800825713962 0.4482234779874887 |
| Detoxification of reactive oxygen species 6 10 -0.7575306472989649 0.4487320120554678 |
| Pkmts methylate histone lysines 3 13 -0.7572055647529726 0.4489267168542659 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 2 8 -0.7547045618488749 0.4504262687388625 |
| Sealing of the nuclear envelope ne by escrt iii 5 10 0.751083665997052 0.452602305244719 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 3 5 -0.747742449113326 0.4546155214695302 |
| Interleukin 15 signaling 2 2 -0.740518034656092 0.4589857222583571 |
| Transcriptional regulation of pluripotent stem cells 2 2 -0.740518034656092 0.4589857222583571 |
| Golgi associated vesicle biogenesis 14 29 -0.7389779805324649 0.4599203682931922 |
| Glycogen synthesis 1 5 -0.7372858711164555 0.4609485224860719 |
| Grb2 sos provides linkage to mapk signaling for integrins 3 4 -0.736156365834311 0.461635543330005 |
| Polo like kinase mediated events 0 5 0.7340466867991293 0.4629202844756945 |
| E3 ubiquitin ligases ubiquitinate target proteins 11 18 -0.7336073755023483 0.4631880645040833 |
| Glycogen breakdown glycogenolysis 2 6 -0.7331493111524633 0.4634673672829394 |
| Netrin mediated repulsion signals 0 2 0.726457837394225 0.467558145763344 |
| Hsf1 activation 6 14 -0.7262840114181437 0.467664678886051 |
| Sema4d induced cell migration and growth cone collapse 4 9 -0.7219910506635495 0.470299979729792 |
| Cytochrome c mediated apoptotic response 3 4 0.721882413704209 0.4703667744473874 |
| Rho gtpases activate nadph oxidases 3 7 -0.7197328566365226 0.4716894922182928 |
| Miscellaneous transport and binding events 2 4 0.712126095409121 0.4763866962828147 |
| Nucleotide catabolism 2 10 -0.7087935325372371 0.4784526118120449 |
| Sumoylation of rna binding proteins 9 32 -0.7080773672176591 0.4788972137129064 |
| Runx2 regulates osteoblast differentiation 0 5 0.7070281053782501 0.4795490121528643 |
| Akt phosphorylates targets in the cytosol 2 4 -0.7051290195672274 0.4807299485989202 |
| Cd163 mediating an anti inflammatory response 2 2 -0.703358938211228 0.4818320892112906 |
| Glycosphingolipid metabolism 3 16 0.6982949557078297 0.48499275320023 |
| Vldl assembly 1 1 -0.6976572505191674 0.4853915689013481 |
| Chylomicron assembly 1 1 -0.6976572505191674 0.4853915689013481 |
| Ldl remodeling 1 1 -0.6976572505191674 0.4853915689013481 |
| Keratan sulfate degradation 1 4 0.6938531178138789 0.4877743271101249 |
| Synthesis of pe 0 1 0.6935930259107497 0.4879374685963267 |
| Translation of sars cov 2 structural proteins 2 13 0.6935913260500894 0.4879385349231606 |
| Prostacyclin signalling through prostacyclin receptor 1 2 0.6862625824689473 0.4925475397777257 |
| Inwardly rectifying k channels 1 2 0.6862625824689473 0.4925475397777257 |
| Potassium channels 1 2 0.6862625824689473 0.4925475397777257 |
| G protein activation 1 2 0.6862625824689473 0.4925475397777257 |
| Glucagon type ligand receptors 1 2 0.6862625824689473 0.4925475397777257 |
| Acyl chain remodelling of ps 1 1 -0.6844762438006593 0.4936744854733477 |
| Ptk6 regulates rtks and their effectors akt1 and dok1 1 2 -0.6821632880755649 0.4951357056418888 |
| Ra biosynthesis pathway 1 3 0.6815077817300695 0.4955502445231565 |
| Vitamin b1 thiamin metabolism 1 1 -0.6800980226792053 0.4964423964056688 |
| Interleukin 6 family signaling 1 4 -0.6788303512530638 0.4972453603360782 |
| Interleukin 6 signaling 1 4 -0.6788303512530638 0.4972453603360782 |
| P38mapk events 2 4 0.6754560500466706 0.4993860652767263 |
| G alpha i signalling events 12 29 0.6738878493672738 0.5003826176033637 |
| Darpp 32 events 1 10 -0.6707624645640674 0.5023718628199012 |
| Unblocking of nmda receptors glutamate binding and activation 0 5 0.6696973191695315 0.5030507609974313 |
| Slc transporter disorders 9 32 -0.6694580680674299 0.5032033205668556 |
| Presynaptic function of kainate receptors 1 3 0.6685741988772992 0.503767135696064 |
| Regulation of tp53 activity through phosphorylation 12 34 0.6678067466376107 0.5042569594443074 |
| Depolymerisation of the nuclear lamina 1 10 -0.6630805286196919 0.507278980467802 |
| Formation of xylulose 5 phosphate 2 3 0.6604050931286147 0.5089939046539951 |
| Vitamin d calciferol metabolism 0 1 0.6543599343285164 0.5128799407957587 |
| Cellular response to heat stress 20 64 -0.6501138574248424 0.5156186787309438 |
| Rhoj gtpase cycle 6 21 -0.6477690543445664 0.5171343333421379 |
| Cytochrome p450 arranged by substrate type 2 3 0.6472301090627541 0.5174830273725406 |
| Synthesis of pips at the golgi membrane 0 8 0.6467331004349419 0.5178046964890259 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 2 16 -0.6449644402196519 0.5189502301109206 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 1 3 -0.6437330588934662 0.5197485487401772 |
| Pyrimidine catabolism 1 1 -0.6396229375859775 0.5224177664845859 |
| 2 ltr circle formation 4 4 -0.6362683049113503 0.5246015596303695 |
| Uptake and function of diphtheria toxin 2 4 -0.6331600178857067 0.5266291521786486 |
| Diseases of carbohydrate metabolism 3 9 -0.6317551932245989 0.5275468563306958 |
| G protein mediated events 3 15 -0.6300614859294029 0.5286543568602515 |
| Notch hlh transcription pathway 1 5 -0.6220043935314504 0.5339389790448901 |
| Rhobtb3 atpase cycle 3 3 -0.6208083402690348 0.5347257350287136 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 1 7 -0.6207191999435493 0.5347843943584314 |
| Signaling by fgfr1 in disease 5 10 -0.6181631211310706 0.5364678172805113 |
| Homology directed repair 12 42 0.6158942073994566 0.5379643449130103 |
| Regulation of mecp2 expression and activity 2 11 -0.6135319979223561 0.5395246319518412 |
| Diseases of dna repair 0 11 0.6133085749379278 0.5396723245668191 |
| Alpha oxidation of phytanate 2 3 0.6131795100439509 0.5397576514743885 |
| Listeria monocytogenes entry into host cells 1 8 0.6127502666037474 0.5400414798893967 |
| Metabolic disorders of biological oxidation enzymes 2 5 0.6116113001913981 0.5407949598571169 |
| Rnd3 gtpase cycle 6 16 -0.6076005278899589 0.5434524506259735 |
| E2f mediated regulation of dna replication 3 12 0.6071572981676877 0.5437465278107876 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 4 7 -0.6061993914850308 0.5443823568245316 |
| Attachment and entry 1 1 -0.6055203639657791 0.544833298133317 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0 4 0.6045612286883268 0.545470574594447 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 6 31 0.6032178358152958 0.5463637839585194 |
| Gdp fucose biosynthesis 1 2 0.5999412986448951 0.5485453576605659 |
| Creatine metabolism 3 3 -0.5978390063508893 0.5499473609570045 |
| Protein repair 1 1 -0.5970848397615958 0.5504507390389299 |
| Heparan sulfate heparin hs gag metabolism 1 3 0.595904716694276 0.5512388820867167 |
| Pka mediated phosphorylation of key metabolic factors 1 1 -0.5942812571851794 0.5523240124351965 |
| Hdl assembly 1 1 -0.5942812571851794 0.5523240124351965 |
| Fcgr activation 2 3 0.5914777372676044 0.5542003675512854 |
| Downregulation of erbb2 signaling 2 6 -0.5906119392937818 0.5547804633275344 |
| Met activates pi3k akt signaling 2 2 -0.5901245115508347 0.5551071767425566 |
| Rna polymerase ii transcribes snrna genes 10 28 -0.5883705421240247 0.5562836058885616 |
| Acyl chain remodelling of pg 0 2 0.5882985686406671 0.556331906182058 |
| Formation of rna pol ii elongation complex 13 33 -0.5876383497853409 0.5567750642682037 |
| Oxidative stress induced senescence 2 15 0.5859072031810422 0.5579378764732332 |
| Deposition of new cenpa containing nucleosomes at the centromere 1 7 0.582494092142168 0.5602339197631059 |
| Hdms demethylate histones 3 9 0.5807909384071742 0.5613813630404738 |
| Activation of nima kinases nek9 nek6 nek7 0 5 0.5807326098093117 0.5614206801204946 |
| Deactivation of the beta catenin transactivating complex 2 9 -0.5802812079464368 0.5617249979044443 |
| Integrin cell surface interactions 1 4 0.5800352774032425 0.5618908283748238 |
| Metabolism of cofactors 1 5 -0.5758070040871225 0.5647456387973628 |
| Regulation of tlr by endogenous ligand 1 1 -0.5747742215698487 0.5654440030963301 |
| Irak4 deficiency tlr2 4 1 1 -0.5747742215698487 0.5654440030963301 |
| Metabolism of nucleotides 4 48 -0.5742027582657714 0.5658306030307148 |
| Transport of mature mrnas derived from intronless transcripts 9 35 -0.5713632633488479 0.5677534260391854 |
| Ros and rns production in phagocytes 1 8 0.567599940523756 0.5703066475473635 |
| Hats acetylate histones 6 23 0.5663982392997775 0.5711230913974412 |
| Trna modification in the nucleus and cytosol 8 22 0.5663208081642563 0.5711757177008494 |
| Cardiac conduction 3 12 0.5651796701259271 0.5719515630954666 |
| Ion homeostasis 3 12 0.5651796701259271 0.5719515630954666 |
| Oas antiviral response 1 3 -0.564713767261138 0.5722684685286872 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0 4 0.563635000268256 0.5730025619087431 |
| Cell cell junction organization 1 8 0.5567051773184982 0.5777288790143253 |
| Activation of atr in response to replication stress 7 18 0.5523515390689238 0.5807075258791012 |
| Antigen presentation folding assembly and peptide loading of class i mhc 1 14 0.5496992415484304 0.5825256771618095 |
| Rab regulation of trafficking 5 36 -0.5488691758043223 0.583095233078573 |
| Irak1 recruits ikk complex 2 3 -0.5487586054061613 0.5831711213927604 |
| Acetylcholine regulates insulin secretion 1 2 -0.5447612832783313 0.5859177099889361 |
| Shc1 events in erbb2 signaling 2 3 -0.5418223020756548 0.5879409261400239 |
| Regulation of lipid metabolism by pparalpha 2 25 0.5403186135457477 0.5889773239640683 |
| Signaling by notch1 pest domain mutants in cancer 1 8 -0.5393083781374777 0.5896740888091028 |
| Signaling by wnt in cancer 2 8 0.538840398280035 0.5899969857804588 |
| Fceri mediated mapk activation 2 8 -0.5383773437762966 0.5903165645069803 |
| Constitutive signaling by overexpressed erbb2 2 5 -0.5375661104943641 0.5908766321112151 |
| Lipophagy 1 4 -0.5373835194322866 0.5910027249027763 |
| Antiviral mechanism by ifn stimulated genes 15 52 -0.5371373437651321 0.5911727472079062 |
| Interleukin 27 signaling 1 3 -0.5361366195400787 0.591864133177489 |
| Interleukin 35 signalling 1 3 -0.5361366195400787 0.591864133177489 |
| Notch3 intracellular domain regulates transcription 2 4 -0.5315829831883941 0.5950148531764023 |
| Telomere c strand synthesis initiation 3 6 -0.5294680261577142 0.5964808190926583 |
| Signal attenuation 1 3 -0.5278973960928498 0.597570552104346 |
| Regulation of insulin secretion 2 14 -0.5277777780910298 0.5976535824154232 |
| Rho gtpases activate rhotekin and rhophilins 1 2 0.5222176390825908 0.6015188059915784 |
| Abc transporters in lipid homeostasis 1 2 -0.5204334486946195 0.602761501897831 |
| Homologous dna pairing and strand exchange 5 16 0.5200804298162051 0.6030075178887553 |
| Dopamine neurotransmitter release cycle 1 3 0.5164404345997456 0.6055468311458818 |
| Wnt5a dependent internalization of fzd4 2 10 -0.5156700353638375 0.6060848862587049 |
| Hdr through single strand annealing ssa 5 15 0.5151338141329129 0.606459515140245 |
| Coenzyme a biosynthesis 1 3 0.5126328761498764 0.6082081515050586 |
| Notch1 intracellular domain regulates transcription 1 9 -0.51187289577839 0.6087399686543757 |
| Runx3 regulates cdkn1a transcription 1 2 -0.511071982609903 0.609300653590682 |
| Activation of rac1 downstream of nmdars 0 1 0.509785325428493 0.6102018675451246 |
| Ntrk2 activates rac1 0 1 0.509785325428493 0.6102018675451246 |
| Killing mechanisms 0 1 0.509785325428493 0.6102018675451246 |
| Activated ntrk2 signals through fyn 0 2 0.5079323899110635 0.6115007588010637 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 2 3 -0.5069017906430636 0.6122237292065398 |
| Beta oxidation of butanoyl coa to acetyl coa 1 4 -0.5062724627740035 0.6126653915900431 |
| Trna processing in the nucleus 13 42 -0.5042234981578653 0.6141043296115734 |
| Met interacts with tns proteins 2 2 -0.5036362313262922 0.6145170272717349 |
| Protein folding 3 33 -0.5005442402432342 0.6166919133684383 |
| Cargo trafficking to the periciliary membrane 3 18 -0.4999562889140596 0.6171058561038145 |
| Loss of mecp2 binding ability to the ncor smrt complex 1 2 -0.4955076267884102 0.6202418397297524 |
| Interconversion of nucleotide di and triphosphates 3 18 -0.4915334179550618 0.6230492223269786 |
| Class b 2 secretin family receptors 1 4 -0.4885607330952379 0.6251527185681895 |
| Response to elevated platelet cytosolic ca2 5 28 0.4881250665570497 0.6254612569893632 |
| Beta oxidation of hexanoyl coa to butanoyl coa 1 5 -0.4876115541611473 0.6258250099886662 |
| Regulation of pten localization 0 1 0.4860965683930251 0.6268986998458779 |
| Cell surface interactions at the vascular wall 6 18 0.4859108465374602 0.6270303777734869 |
| Pi 3k cascade fgfr3 1 2 -0.4840888331477571 0.628322825996406 |
| Pi 3k cascade fgfr1 1 2 -0.4840888331477571 0.628322825996406 |
| Pi 3k cascade fgfr2 1 2 -0.4840888331477571 0.628322825996406 |
| Stat5 activation downstream of flt3 itd mutants 1 2 -0.4840888331477571 0.628322825996406 |
| Pi 3k cascade fgfr4 1 2 -0.4840888331477571 0.628322825996406 |
| Stat5 activation 1 2 -0.4840888331477571 0.628322825996406 |
| Pecam1 interactions 2 5 0.4828642791405737 0.6291921064374999 |
| Glycerophospholipid catabolism 1 2 -0.4802108974694598 0.631077438802532 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 4 20 0.4796914243711209 0.6314468266265494 |
| G2 m dna replication checkpoint 0 4 0.4763996727814981 0.6337896677470858 |
| Phosphorylation of emi1 0 3 0.4763912525304827 0.6337956654225321 |
| Negative regulation of mapk pathway 5 14 0.4749772448202981 0.6348031924602113 |
| Cell death signalling via nrage nrif and nade 2 9 -0.4725234633979207 0.6365531981271166 |
| Rip mediated nfkb activation via zbp1 0 4 0.4721552665217048 0.6368159668303783 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 2 2 -0.4704794185223568 0.6380125352897459 |
| Folding of actin by cct tric 8 8 -0.4677948683023791 0.6399312907567223 |
| Platelet homeostasis 4 12 0.464062467854812 0.6426029908513422 |
| Tp53 regulates transcription of death receptors and ligands 1 2 -0.4640388675629695 0.6426198990091232 |
| Rna polymerase ii transcription termination 12 43 -0.4611116959490572 0.6447184708936757 |
| Integration of provirus 0 5 0.4598753293674659 0.6456057092256478 |
| Transport of the slbp dependant mature mrna 8 31 -0.4591994100216701 0.6460909742061234 |
| Interleukin 12 signaling 9 27 0.4590311152811002 0.6462118220281186 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 2 2 -0.4590145360162443 0.6462237276471909 |
| Ns1 mediated effects on host pathways 9 34 -0.4581510218485756 0.6468439449127441 |
| Netrin 1 signaling 3 12 -0.4577415255951576 0.6471381505593634 |
| Met activates ptk2 signaling 3 4 -0.4563937414915209 0.6481068654080677 |
| Rac2 gtpase cycle 9 35 -0.4556539784936395 0.6486388207864595 |
| Mitochondrial fatty acid beta oxidation 3 18 -0.4554844751509506 0.6487607340251782 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 1 8 0.4539795401932096 0.6498435528380835 |
| Raf activation 5 17 0.4536362761208825 0.6500906391893553 |
| Activation of smo 3 3 -0.4529786417173043 0.6505641212220314 |
| Nr1h2 and nr1h3 mediated signaling 0 6 0.452764693323482 0.6507181896910765 |
| Hcmv late events 10 36 -0.4525757106666978 0.65085429225365 |
| Interleukin 12 family signaling 9 30 0.4521024977376842 0.6511951443886643 |
| Semaphorin interactions 13 26 -0.450150103681496 0.6526022113828596 |
| Synthesis of leukotrienes lt and eoxins ex 1 1 -0.4471709872659474 0.6547516075735698 |
| Biosynthesis of epa derived spms 1 1 -0.4471709872659474 0.6547516075735698 |
| Biosynthesis of specialized proresolving mediators spms 1 1 -0.4471709872659474 0.6547516075735698 |
| Tp53 regulates transcription of cell death genes 2 7 0.4450806559260774 0.6562614676265945 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0 3 0.4442330105697343 0.6568741282253607 |
| Nuclear signaling by erbb4 1 4 0.443803247567593 0.6571848402416796 |
| Activation of nmda receptors and postsynaptic events 8 25 0.4434508822084781 0.6574396391772499 |
| Response of mtb to phagocytosis 1 12 0.4428490213403745 0.6578749428987671 |
| Infection with mycobacterium tuberculosis 1 12 0.4428490213403745 0.6578749428987671 |
| Aspartate and asparagine metabolism 2 5 0.4417556743720861 0.6586660171294458 |
| Nicotinamide salvaging 1 2 0.4402000076123794 0.6597922542296437 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 6 9 -0.439873102193944 0.6600290181309876 |
| Signaling by mapk mutants 0 2 0.4392199914416447 0.6605021408342875 |
| Mismatch repair 0 13 0.4384540522445652 0.66105717099237 |
| Diseases associated with n glycosylation of proteins 0 6 0.4365803405104662 0.6624157227233469 |
| G alpha q signalling events 4 13 -0.434043170334749 0.6642570922885604 |
| Signaling by alk 1 6 0.4337902698367886 0.6644407480067054 |
| Trafficking of glur2 containing ampa receptors 2 7 0.4336614198924809 0.6645343262672543 |
| Myoclonic epilepsy of lafora 0 1 0.4320268914182297 0.6657218685860247 |
| Tysnd1 cleaves peroxisomal proteins 2 5 0.4316954502033915 0.6659627746475496 |
| Negative regulation of fgfr1 signaling 0 7 0.4315391748811 0.6660763743892404 |
| Negative regulation of fgfr4 signaling 0 7 0.4315391748811 0.6660763743892404 |
| Spry regulation of fgf signaling 0 7 0.4315391748811 0.6660763743892404 |
| Negative regulation of fgfr2 signaling 0 7 0.4315391748811 0.6660763743892404 |
| Negative regulation of fgfr3 signaling 0 7 0.4315391748811 0.6660763743892404 |
| Rmts methylate histone arginines 7 19 0.4311599212787532 0.6663520934752125 |
| Hdacs deacetylate histones 5 16 -0.4284927305760508 0.6682924249420863 |
| Signaling by flt3 fusion proteins 2 6 -0.426396622153924 0.6698188623295458 |
| Interleukin 20 family signaling 1 3 -0.4260298506400192 0.6700860947738498 |
| Signaling by bmp 2 2 -0.4235198217482249 0.6719160396887107 |
| Inositol phosphate metabolism 0 9 0.423244685168219 0.6721167474663143 |
| Recycling pathway of l1 5 20 0.4226332777229521 0.6725628431785147 |
| Rab gefs exchange gtp for gdp on rabs 4 26 -0.4219343364718385 0.6730729466117475 |
| Transcriptional activation of mitochondrial biogenesis 3 16 -0.4211713295033339 0.6736299784486928 |
| Transmission across chemical synapses 17 50 0.4197657438911138 0.6746565921385628 |
| Cd209 dc sign signaling 1 5 -0.4127104919009655 0.6798187369274291 |
| Interleukin 7 signaling 2 2 -0.4116394610247314 0.6806037037098114 |
| Rac3 gtpase cycle 9 34 -0.4086434226337956 0.6828013594393347 |
| G2 m dna damage checkpoint 5 33 0.4080186462094847 0.6832599855854069 |
| Formation of the beta catenin tcf transactivating complex 2 10 0.4071343356749579 0.6839093263283376 |
| Extra nuclear estrogen signaling 6 14 0.4063209334779707 0.6845068062231834 |
| Translation of sars cov 1 structural proteins 5 5 -0.405857922343033 0.6848469966131938 |
| Tyrosine catabolism 0 2 0.4050408896748024 0.685447454850971 |
| Fcgr3a mediated il10 synthesis 1 9 -0.4010961189358971 0.688349358153677 |
| Rho gtpases activate iqgaps 3 10 0.4003310332068732 0.6889127136344677 |
| Diseases of base excision repair 0 1 0.399918146005954 0.6892168065300137 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 1 3 0.3997731517136639 0.6893236072591149 |
| Mastl facilitates mitotic progression 2 5 0.3975972678910569 0.6909270747569087 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 2 4 -0.397548677905063 0.6909628978940334 |
| Prevention of phagosomal lysosomal fusion 2 4 -0.3954674801319005 0.6924979168764336 |
| P75ntr negatively regulates cell cycle via sc1 1 2 0.3951728066354308 0.6927153600592963 |
| Mitochondrial trna aminoacylation 8 19 0.39322131672168 0.6941560267567413 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 1 10 -0.3910010228863885 0.6957964797747007 |
| Regulation of commissural axon pathfinding by slit and robo 0 2 0.390341191914014 0.6962842675256504 |
| Signaling by leptin 1 2 -0.3885880350694335 0.6975809191526305 |
| Wnt mediated activation of dvl 1 2 0.3876530005484083 0.6982728411977646 |
| Vegfr2 mediated vascular permeability 4 9 -0.3867858575199761 0.698914747990274 |
| Ticam1 rip1 mediated ikk complex recruitment 0 4 0.3844658141318002 0.7006332288871886 |
| Metabolism of fat soluble vitamins 2 3 0.3836787572550862 0.701216559072207 |
| Transcriptional regulation of white adipocyte differentiation 8 17 -0.3823877862699998 0.7021737484514274 |
| Downregulation of erbb4 signaling 1 2 0.3816903661269812 0.7026910467660725 |
| Incretin synthesis secretion and inactivation 2 5 0.3816647959790978 0.7027100155624302 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 2 5 0.3816647959790978 0.7027100155624302 |
| Regulation of glucokinase by glucokinase regulatory protein 8 27 -0.3764180975017567 0.7066060938242253 |
| Sumoylation of sumoylation proteins 8 27 -0.3764180975017567 0.7066060938242253 |
| Rrna processing in the mitochondrion 3 8 0.3741788880060356 0.7082712299684895 |
| Translocation of slc2a4 glut4 to the plasma membrane 9 34 -0.3722535731151957 0.7097040619192758 |
| Deadenylation of mrna 8 16 -0.372062606362358 0.709846236702453 |
| Uch proteinases 10 48 0.3713598376489509 0.7103695351002244 |
| Insulin processing 7 7 -0.3690031337759226 0.7121253889457804 |
| Sensory perception 8 26 0.3688379270118541 0.712248533052936 |
| Sars cov 2 infection 4 20 0.3683937861294416 0.712579630134526 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 5 11 0.3638598003888623 0.7159627045902497 |
| Plasma lipoprotein assembly remodeling and clearance 3 14 0.3631443796630341 0.7164970340109678 |
| Export of viral ribonucleoproteins from nucleus 8 29 -0.3631250250217499 0.7165114914268345 |
| Fatty acid metabolism 14 53 0.3611291271713916 0.7180029200870361 |
| Hcmv early events 12 47 -0.3592797872918798 0.719385793684792 |
| Fatty acyl coa biosynthesis 1 16 -0.3587736237728151 0.7197644459688699 |
| Transport of fatty acids 0 1 0.3583527604020313 0.7200793390340645 |
| Initiation of nuclear envelope ne reformation 1 17 -0.3566899726280483 0.7213239131039257 |
| Binding and uptake of ligands by scavenger receptors 0 6 0.3557398053661327 0.7220354321066944 |
| Pi3k akt signaling in cancer 6 12 -0.3555452749369738 0.7221811330863166 |
| Raf independent mapk1 3 activation 0 6 0.352446140029202 0.7245037042387834 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 8 25 0.3506017838217115 0.725887118094455 |
| Insulin receptor signalling cascade 2 6 -0.3504922977711308 0.7259692695187605 |
| Aggrephagy 4 16 0.349289723335314 0.726871812790689 |
| Signaling by insulin receptor 3 15 0.3479595010760786 0.7278705985913749 |
| Transport and synthesis of paps 2 3 0.3471134592834836 0.7285060823778111 |
| Atf4 activates genes in response to endoplasmic reticulum stress 2 13 0.3459893712793141 0.7293507025130836 |
| L1cam interactions 8 39 0.3455277102689391 0.7296976817816028 |
| Rho gtpases activate rocks 4 12 -0.3430187152898731 0.7315843806280902 |
| Late endosomal microautophagy 2 8 -0.3428608338180051 0.7317031578169355 |
| Apoptosis induced dna fragmentation 2 11 -0.3415021391599292 0.7327255947452085 |
| Regulation of signaling by cbl 1 5 -0.3394189108247216 0.7342941744725384 |
| Transport of inorganic cations anions and amino acids oligopeptides 2 11 0.3391929410742319 0.7344643866110505 |
| Negative epigenetic regulation of rrna expression 5 25 -0.3379737736748629 0.7353829516322534 |
| Eph ephrin signaling 7 33 -0.3362676588621913 0.736669035831377 |
| Oncogene induced senescence 1 7 -0.3348078164084889 0.7377700638473397 |
| Signaling by met 8 20 -0.3329990520223798 0.7391349987362901 |
| Telomere c strand lagging strand synthesis 5 23 -0.3285729925343454 0.7424784644447422 |
| Flt3 signaling by cbl mutants 0 1 0.3282683079901524 0.7427088042291301 |
| Synthesis of gdp mannose 0 2 0.3265209550137835 0.7440302375138752 |
| Signaling by retinoic acid 2 10 -0.3251515349638139 0.7450663868468661 |
| Gab1 signalosome 0 4 0.3246247432024656 0.7454650982346438 |
| Syndecan interactions 1 3 -0.3243095835928383 0.7457036648023629 |
| Non integrin membrane ecm interactions 1 3 -0.3243095835928383 0.7457036648023629 |
| Regulation of bach1 activity 2 4 0.32256272586839 0.7470264263705544 |
| Toll like receptor 9 tlr9 cascade 5 18 -0.3212785550338609 0.7479993062886527 |
| Cilium assembly 12 55 -0.3197030083270921 0.7491934790687287 |
| Nuclear import of rev protein 8 31 -0.3181612202355114 0.7503626472653662 |
| Irs mediated signalling 2 4 -0.3167177982521294 0.7514577424872309 |
| Maturation of sars cov 2 nucleoprotein 0 4 0.3150017141850772 0.752760352343979 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 1 6 0.3144438165333869 0.7531839817166055 |
| Beta catenin phosphorylation cascade 1 6 0.3144438165333869 0.7531839817166055 |
| Signaling by ctnnb1 phospho site mutants 1 6 0.3144438165333869 0.7531839817166055 |
| Early phase of hiv life cycle 1 7 -0.3106625381858441 0.7560571791706177 |
| Keratinization 1 7 0.3089697595368497 0.757344530489156 |
| Formation of the cornified envelope 1 7 0.3089697595368497 0.757344530489156 |
| Nod1 2 signaling pathway 3 8 -0.3075269787838554 0.7584422911810502 |
| Rhoq gtpase cycle 5 22 -0.3075218465686436 0.7584461969723342 |
| Pyroptosis 1 6 0.3058525801739383 0.7597168923143753 |
| Pentose phosphate pathway 4 10 0.3057131248468634 0.7598230792818141 |
| Signalling to ras 2 5 0.3055591599069039 0.759940319717801 |
| Flt3 signaling in disease 2 8 -0.3030691461137266 0.7618371668637278 |
| G1 s specific transcription 3 8 0.3023911815450646 0.7623538763951656 |
| Signaling by notch1 1 11 -0.2997544931124088 0.7643644291877492 |
| Flt3 signaling 1 6 -0.2997462560508411 0.7643707126879264 |
| Plasma lipoprotein remodeling 0 2 0.2994378943193725 0.7646059522680384 |
| Pre notch processing in golgi 0 2 0.2990575519391932 0.7648961335649764 |
| Sema3a pak dependent axon repulsion 4 7 -0.2985546100404768 0.7652799025440917 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 2 12 0.2973216302408701 0.766220969365216 |
| Creb phosphorylation 1 1 -0.2961612998294088 0.7671069020123411 |
| Activation of the ap 1 family of transcription factors 1 2 -0.2919168455197495 0.7703502033292455 |
| Ret signaling 2 7 -0.291567271481627 0.7706175021757318 |
| Metabolism of ingested semet sec mesec into h2se 1 2 -0.2907365547195016 0.7712528120048332 |
| Vldlr internalisation and degradation 1 7 -0.2897009039481955 0.7720450647183628 |
| Maturation of sars cov 1 nucleoprotein 0 1 0.2892100531231291 0.7724206391471933 |
| Fcgamma receptor fcgr dependent phagocytosis 3 34 0.2861322829711503 0.7747768064932878 |
| G0 and early g1 3 6 0.2839172634560227 0.7764737863440918 |
| Traf3 dependent irf activation pathway 2 3 -0.2820660817479611 0.7778928405093892 |
| Response of eif2ak1 hri to heme deficiency 5 5 -0.2813870799252975 0.778413526684059 |
| Defective ripk1 mediated regulated necrosis 0 2 0.2803180739479999 0.7792334854233087 |
| Perk regulates gene expression 2 16 0.2797375917901952 0.7796788351630926 |
| Interleukin 21 signaling 1 2 -0.2789006886043457 0.7803210400717742 |
| Interleukin 9 signaling 1 2 -0.2789006886043457 0.7803210400717742 |
| Endogenous sterols 1 2 0.2730231032543825 0.7848354561822655 |
| Ras signaling downstream of nf1 loss of function variants 1 2 0.2711883803574845 0.7862461493760211 |
| Uptake and function of anthrax toxins 2 3 -0.2701347342262675 0.7870566010375069 |
| Smac xiap regulated apoptotic response 2 3 0.2697673978194781 0.7873392059691513 |
| Activation of caspases through apoptosome mediated cleavage 2 3 0.2697673978194781 0.7873392059691513 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 1 1 -0.2690588011857516 0.7878844335901523 |
| Runx3 regulates wnt signaling 1 1 -0.2690588011857516 0.7878844335901523 |
| Binding of tcf lef ctnnb1 to target gene promoters 1 1 -0.2690588011857516 0.7878844335901523 |
| Myd88 independent tlr4 cascade 1 19 0.2664485865794451 0.7898937504752028 |
| Amyloid fiber formation 1 3 0.2635367252078304 0.7921369210232512 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 1 7 -0.2629445359160057 0.7925933290260476 |
| Sumoylation of dna methylation proteins 0 4 0.2618942221547255 0.7934029942496916 |
| Signaling by ntrk3 trkc 1 5 0.2615519964425862 0.7936668571486774 |
| Sensing of dna double strand breaks 1 4 -0.259719514139881 0.7950801389459936 |
| Maturation of sars cov 1 spike protein 4 4 -0.2591057576471031 0.7955536425068104 |
| The role of gtse1 in g2 m progression after g2 checkpoint 11 50 0.25904816299681 0.7955980797486519 |
| Vegfr2 mediated cell proliferation 2 6 0.2580242663130915 0.7963881793578871 |
| G protein beta gamma signalling 2 6 0.2577731408712366 0.7965819946022954 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 2 3 -0.2565566486463727 0.7975210443610556 |
| Gp1b ix v activation signalling 2 3 -0.2551475350894164 0.798609151097811 |
| Transport of mature transcript to cytoplasm 16 63 -0.2527160091125756 0.8004876758804393 |
| Basigin interactions 2 6 0.2526700639394285 0.8005231829052692 |
| Downstream signaling of activated fgfr3 2 4 -0.2521693720143151 0.8009101508163834 |
| Downstream signaling of activated fgfr2 2 4 -0.2521693720143151 0.8009101508163834 |
| Downstream signaling of activated fgfr1 2 4 -0.2521693720143151 0.8009101508163834 |
| Downstream signaling of activated fgfr4 2 4 -0.2521693720143151 0.8009101508163834 |
| Cell cell communication 14 30 -0.2519074798330311 0.8011125779236956 |
| Hyaluronan metabolism 1 3 0.2518286625395824 0.8011735016270887 |
| Hyaluronan uptake and degradation 1 3 0.2518286625395821 0.8011735016270889 |
| Synthesis of pa 1 7 0.2514432212115272 0.8014714550878455 |
| Purine ribonucleoside monophosphate biosynthesis 9 10 0.2508731036099195 0.8019122197475548 |
| The activation of arylsulfatases 0 3 0.2508216697137286 0.8019519870033769 |
| Fanconi anemia pathway 0 7 0.2473048145216886 0.8046723330455952 |
| Parasite infection 16 26 0.2464213696302145 0.8053560655996215 |
| Caspase activation via extrinsic apoptotic signalling pathway 0 5 0.2455583706287384 0.8060241180200429 |
| Prolactin receptor signaling 3 4 0.2448579713751511 0.8065664051597952 |
| Linoleic acid la metabolism 1 2 0.244038248665865 0.8072011971085473 |
| Interactions of vpr with host cellular proteins 8 33 -0.2425712679216162 0.8083375413836189 |
| Constitutive signaling by aberrant pi3k in cancer 3 7 -0.2423992474286848 0.8084708174562281 |
| Recycling of eif2 gdp 2 8 0.2420783844488173 0.8087194268585258 |
| Dna methylation 0 4 0.2408696892724966 0.8096561150230552 |
| Mapk targets nuclear events mediated by map kinases 1 7 -0.240569176744622 0.80988904203809 |
| Erk mapk targets 1 7 -0.240569176744622 0.80988904203809 |
| Adora2b mediated anti inflammatory cytokines production 5 10 0.2403308887791225 0.8100737508171176 |
| Interleukin 17 signaling 3 14 -0.2392488067566278 0.810912659012271 |
| Camk iv mediated phosphorylation of creb 1 3 0.2390377630222321 0.8110763007110604 |
| Zbp1 dai mediated induction of type i ifns 0 5 0.2375573316285236 0.812224447584476 |
| Plasma lipoprotein clearance 2 11 0.2364430334918629 0.8130889067481728 |
| Condensation of prometaphase chromosomes 4 10 -0.2356570474316735 0.813698802393557 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0 4 0.2353855160480963 0.8139095268177461 |
| Regulation of tp53 activity 17 53 0.2352403912331543 0.814022157787297 |
| Regulation of runx3 expression and activity 7 40 0.2352301729579104 0.8140300883075255 |
| Regulation of tp53 activity through association with co factors 0 1 0.2345111698561885 0.8145881626493092 |
| Activation of noxa and translocation to mitochondria 0 1 0.2345111698561885 0.8145881626493092 |
| Activation of puma and translocation to mitochondria 0 1 0.2345111698561885 0.8145881626493092 |
| Tp53 regulates transcription of genes involved in cytochrome c release 0 1 0.2345111698561885 0.8145881626493092 |
| Synthesis of ip2 ip and ins in the cytosol 1 3 0.2332390146988593 0.8155758117957201 |
| Cell junction organization 3 17 0.2322456405797016 0.8163472306309907 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 2 13 0.231059552001003 0.8172685377036384 |
| Tgf beta receptor signaling activates smads 3 11 0.2304811950025479 0.8177178743940019 |
| Mitochondrial translation 22 60 0.2301954173309003 0.8179399226911956 |
| Bmal1 clock npas2 activates circadian gene expression 0 3 0.2293844245506169 0.818570140866443 |
| Runx2 regulates bone development 0 7 0.2286196336884975 0.819164563204289 |
| Apoptosis 21 91 -0.2274410403333662 0.8200808107821314 |
| Signaling by pdgf 4 9 -0.2273671601684165 0.8201382539872575 |
| Downstream signal transduction 4 9 -0.2273671601684165 0.8201382539872575 |
| Regulation of hmox1 expression and activity 8 49 0.226728974929171 0.8206344950407536 |
| Pi5p regulates tp53 acetylation 1 4 0.2266662948606543 0.8206832377800564 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 1 2 0.2262535689042597 0.8210042086653919 |
| Synthesis secretion and deacylation of ghrelin 1 2 0.2262535689042597 0.8210042086653919 |
| Irf3 mediated activation of type 1 ifn 1 2 -0.2241378399821729 0.8226500493609277 |
| Intra golgi traffic 0 9 0.2234121947154949 0.8232147141601309 |
| Slc mediated transmembrane transport 7 20 0.2230122034953985 0.8235260086557004 |
| Oncogenic mapk signaling 7 32 0.2222868509637531 0.8240905874790418 |
| Negative feedback regulation of mapk pathway 1 3 -0.2219869477156396 0.8243240440712267 |
| Extracellular matrix organization 11 27 0.2219301598258454 0.8243682517694815 |
| Acyl chain remodelling of pi 1 1 -0.2194825834836709 0.8262741454943872 |
| Platelet sensitization by ldl 1 6 -0.218263819086134 0.8272235630383196 |
| Base excision repair ap site formation 1 6 -0.2178581791013359 0.8275396127037844 |
| Tp53 regulates transcription of dna repair genes 10 31 -0.2168044612194377 0.828360735100611 |
| Sumoylation of ubiquitinylation proteins 8 30 -0.2152797570249746 0.8295492111776999 |
| Map3k8 tpl2 dependent mapk1 3 activation 1 4 -0.2152167504450444 0.8295983319450715 |
| Regulation of pten gene transcription 3 22 0.2149923029789628 0.8297733195849837 |
| Regulation of pyruvate dehydrogenase pdh complex 2 7 0.21485855042123 0.8298776020978373 |
| Signaling by egfr 1 12 0.214668798125536 0.8300255509236969 |
| Signaling by activin 1 2 -0.2137402129725693 0.8307496504967817 |
| Signaling by nodal 1 2 -0.2137402129725693 0.8307496504967817 |
| Neuronal system 19 60 0.2134224673904914 0.8309974577291568 |
| Phospholipid metabolism 6 44 0.2105600039227112 0.8332306247925889 |
| Nuclear receptor transcription pathway 2 4 -0.2104430435338129 0.8333219008508896 |
| Regulation of pten stability and activity 8 42 0.210289304237553 0.8334418826394536 |
| Deadenylation dependent mrna decay 4 41 0.2093984297291297 0.8341372184889424 |
| Copi mediated anterograde transport 8 55 0.2080939310955553 0.8351556257251931 |
| Cell extracellular matrix interactions 5 8 -0.2060915850874411 0.8367193718105397 |
| N glycan trimming in the er and calnexin calreticulin cycle 7 13 -0.2059712991220084 0.8368133305855465 |
| Triglyceride metabolism 1 7 0.2051473449013796 0.8374570070874805 |
| Triglyceride catabolism 1 7 0.2051473449013796 0.8374570070874805 |
| Sumoylation of chromatin organization proteins 9 36 -0.2044185790149604 0.8380264127573258 |
| Irs activation 1 1 -0.2040484805376438 0.8383156138011645 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 5 15 0.2037513486151567 0.8385478133856719 |
| Energy dependent regulation of mtor by lkb1 ampk 3 8 -0.203653092427194 0.8386246007101152 |
| Peroxisomal protein import 8 17 0.2034296172187822 0.8387992525642296 |
| Esr mediated signaling 14 44 0.2031981655658108 0.838980146593336 |
| Ncam signaling for neurite out growth 3 9 0.2011059348317812 0.8406157414752928 |
| Scf skp2 mediated degradation of p27 p21 18 42 0.2008873828292168 0.8407866336501522 |
| Nrcam interactions 0 2 0.2000578629947034 0.8414353275810096 |
| Ionotropic activity of kainate receptors 0 2 0.2000578629947034 0.8414353275810096 |
| Signaling by erbb2 6 14 -0.1974105029282457 0.8435063111970584 |
| Aryl hydrocarbon receptor signalling 0 3 0.1966804532427462 0.8440776073660576 |
| Negative regulation of nmda receptor mediated neuronal transmission 0 6 0.1959639905398299 0.8446383508823403 |
| Irak2 mediated activation of tak1 complex 1 1 -0.1952301996184734 0.8452127380365977 |
| Alpha protein kinase 1 signaling pathway 1 1 -0.1952301996184734 0.8452127380365977 |
| Ticam1 traf6 dependent induction of tak1 complex 1 1 -0.1952301996184734 0.8452127380365977 |
| Abortive elongation of hiv 1 transcript in the absence of tat 5 15 0.1942947680086433 0.845945082101315 |
| Ptk6 regulates cell cycle 1 2 0.1939270163229228 0.8462330292829026 |
| Regulation of kit signaling 0 5 0.1937713837005198 0.8463548948021531 |
| Ksrp khsrp binds and destabilizes mrna 5 14 -0.1927002508186477 0.84719372701037 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 1 3 -0.1919981199776217 0.8477436780706173 |
| Hdr through homologous recombination hrr 6 26 0.1916943512094222 0.8479816310136217 |
| Cargo concentration in the er 5 15 0.1908193881295235 0.8486670982568199 |
| Calcineurin activates nfat 0 2 0.1898340563394936 0.849439168013929 |
| Sensory processing of sound by outer hair cells of the cochlea 0 13 0.1896142873208633 0.8496113906601006 |
| Cytosolic trna aminoacylation 16 23 -0.1887647567291196 0.8502771952591508 |
| G beta gamma signalling through cdc42 1 4 0.187239977753525 0.8514724813632468 |
| Nuclear pore complex npc disassembly 8 31 -0.1867641266850066 0.851845574721479 |
| Rna polymerase i transcription termination 6 11 -0.1863385119581329 0.8521793081255158 |
| Budding and maturation of hiv virion 2 7 0.1860034494529504 0.8524420562634418 |
| Acyl chain remodeling of cl 2 3 -0.1856227195918452 0.8527406355421889 |
| Gastrin creb signalling pathway via pkc and mapk 1 4 -0.1856166123263981 0.8527454252070208 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 1 4 0.1848883372262716 0.8533166188306873 |
| Signaling by erythropoietin 2 5 -0.1844136078936519 0.853688995339545 |
| Nrage signals death through jnk 1 6 -0.1842573537120629 0.8538115678665608 |
| Post translational protein modification 75 403 0.1828054727031842 0.8549506543785323 |
| Role of phospholipids in phagocytosis 0 4 0.1823842630325975 0.8552811749619318 |
| Beta oxidation of octanoyl coa to hexanoyl coa 4 5 0.1821507405256335 0.8554644295515443 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 4 5 0.1821507405256335 0.8554644295515443 |
| Erythrocytes take up carbon dioxide and release oxygen 0 1 0.1816038352280994 0.855893638825544 |
| Intrinsic pathway of fibrin clot formation 0 2 0.1808910963191286 0.8564530576725882 |
| Formation of fibrin clot clotting cascade 0 2 0.1808910963191286 0.8564530576725882 |
| Retrograde transport at the trans golgi network 1 10 0.1807884003845395 0.8565336682335702 |
| Piwi interacting rna pirna biogenesis 3 9 0.1806754724656954 0.8566223120572509 |
| Sensory processing of sound 1 19 0.179683312803604 0.8574011946700624 |
| Death receptor signalling 9 22 0.179658764188828 0.8574204680185527 |
| Galactose catabolism 1 2 0.178881775278503 0.8580305331876481 |
| Retrograde neurotrophin signalling 1 8 -0.1787278898092011 0.8581513688768434 |
| Epigenetic regulation of gene expression 13 46 -0.1784418131752742 0.8583760140378598 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 1 3 -0.1783925722506106 0.8584146822310137 |
| Abc family proteins mediated transport 6 50 -0.1765474238887417 0.8598638948637689 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 6 11 -0.1755655266439287 0.8606352873701242 |
| Nade modulates death signalling 1 3 -0.1744238771029195 0.8615323507195332 |
| Regulation of pten mrna translation 0 1 0.1741532723136593 0.8617450075634243 |
| Competing endogenous rnas cernas regulate pten translation 0 1 0.1741532723136593 0.8617450075634243 |
| Glutathione synthesis and recycling 1 6 0.1740932817666496 0.861792152951451 |
| Cd28 co stimulation 2 9 -0.1730848753475883 0.8625847132450024 |
| Erythropoietin activates ras 1 4 -0.17304421969274 0.8626166695952051 |
| Translesion synthesis by polk 5 9 0.1722591975216214 0.8632337604570834 |
| Branched chain amino acid catabolism 7 15 0.1721742007182028 0.8633005798265294 |
| Signaling by gpcr 8 50 -0.1712224233752795 0.8640488765433025 |
| Regulation of ifng signaling 3 4 0.1697232928692926 0.8652277547760634 |
| Gaba synthesis release reuptake and degradation 2 4 0.1696306873872894 0.8653005872442474 |
| Cdt1 association with the cdc6 orc origin complex 7 41 0.1692187687685821 0.8656245673376131 |
| Runx2 regulates chondrocyte maturation 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx1 regulates transcription of genes involved in differentiation of keratinocytes 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx1 regulates transcription of genes involved in bcr signaling 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx2 regulates genes involved in cell migration 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx1 regulates estrogen receptor mediated transcription 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx1 regulates transcription of genes involved in wnt signaling 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx3 regulates immune response and cell migration 1 1 -0.1691353815316828 0.8656901553845859 |
| Runx1 regulates transcription of genes involved in interleukin signaling 1 1 -0.1691353815316828 0.8656901553845859 |
| Scavenging by class a receptors 2 2 -0.1682334883411267 0.866399596496803 |
| Atf6 atf6 alpha activates chaperones 2 2 -0.1682334883411267 0.866399596496803 |
| Atf6 atf6 alpha activates chaperone genes 2 2 -0.1682334883411267 0.866399596496803 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 2 3 0.1673837711826977 0.8670680937511352 |
| Infectious disease 76 349 0.1669759830018263 0.8673889463936129 |
| Rrna modification in the nucleus and cytosol 18 56 0.1668868051785688 0.8674591154900457 |
| Platelet activation signaling and aggregation 12 53 0.1662790453516034 0.8679373558634784 |
| Arms mediated activation 1 1 -0.1635049613173277 0.8701208671523617 |
| Dap12 signaling 2 4 -0.1626887012605865 0.870763543553458 |
| Free fatty acids regulate insulin secretion 2 3 0.1626504571294365 0.8707936568875216 |
| Dna damage reversal 0 5 0.1621461793883671 0.8711907414334257 |
| Sumoylation of transcription cofactors 1 15 0.1615638506969223 0.8716493262037885 |
| Pi metabolism 10 20 -0.1605539407937956 0.8724447340705477 |
| Polymerase switching 7 14 0.1603984277922031 0.8725672280257111 |
| Cytoprotection by hmox1 12 68 0.1591432086523664 0.8735560464069219 |
| Unfolded protein response upr 6 39 0.1588842417266096 0.8737600762588249 |
| Interleukin 23 signaling 2 2 -0.1586446953932289 0.8739488128647677 |
| Dissolution of fibrin clot 2 2 -0.1580889518667966 0.8743867062700521 |
| Signalling to erks 3 10 -0.1542624775936248 0.8774027816679442 |
| Inlb mediated entry of listeria monocytogenes into host cell 2 5 -0.154154638082804 0.8774878081378121 |
| Tp53 regulates transcription of cell cycle genes 5 14 0.1532725752599451 0.8781833268811658 |
| Negative regulation of met activity 3 7 -0.1531246342126115 0.8782999896675621 |
| Fceri mediated ca 2 mobilization 2 5 -0.1528604998779722 0.8785082862828237 |
| Transcriptional regulation by runx2 9 56 0.1523042303049697 0.8789469885455579 |
| Viral messenger rna synthesis 8 35 -0.1515836256471368 0.8795153489939618 |
| Mecp2 regulates transcription of neuronal ligands 1 3 0.1505360752879936 0.8803416910420934 |
| Srp dependent cotranslational protein targeting to membrane 24 89 0.1501766401033461 0.8806252553669298 |
| Signaling by fgfr 5 26 0.1501000551081375 0.8806856765077911 |
| Signaling by fgfr2 5 26 0.1501000551081375 0.8806856765077911 |
| Vxpx cargo targeting to cilium 7 8 0.1500183340106092 0.8807501505029296 |
| Cyclin a cdk2 associated events at s phase entry 18 44 0.1496456819566847 0.8810441649716243 |
| Innate immune system 50 287 0.1488525946754516 0.8816699483368531 |
| Rho gtpases activate wasps and waves 12 20 0.1485708716816858 0.8818922589030058 |
| Gap junction trafficking and regulation 3 12 0.148165198500004 0.8822123962035402 |
| Regulation of runx2 expression and activity 7 47 0.148051807387729 0.882301882329471 |
| Dna double strand break repair 6 55 0.1479538430613123 0.8823791951367825 |
| Hcmv infection 15 55 -0.1468812998340342 0.8832257123918883 |
| Erks are inactivated 4 5 0.1460991973814386 0.8838430800159058 |
| Signal transduction by l1 2 10 0.1453460974567418 0.8844376206122639 |
| Activated ntrk2 signals through cdk5 1 2 0.1453058040775851 0.8844694323711537 |
| Hdl clearance 0 2 0.1442339753973519 0.8853157129479214 |
| Vitamin b5 pantothenate metabolism 1 5 0.143256984129782 0.8860872270426801 |
| Signaling by erbb4 2 8 -0.1423488492059334 0.8868044632604495 |
| Estrogen stimulated signaling through prkcz 1 2 0.1422619678838187 0.8868730861609921 |
| Formation of apoptosome 1 2 0.14226196788381 0.886873086160999 |
| Dcc mediated attractive signaling 2 6 -0.1412074024608275 0.8877060983553708 |
| Rho gtpases activate ktn1 1 8 -0.1406705161872216 0.8881302381187561 |
| B wich complex positively regulates rrna expression 10 17 -0.1405912165951452 0.8881928874565514 |
| Signaling by ptk6 2 13 -0.1401284297956855 0.8885585184719889 |
| Miro gtpase cycle 1 5 0.1395837517079319 0.8889888791863567 |
| Ephrin signaling 1 4 -0.1395226888697094 0.8890371281604528 |
| Signaling by fgfr4 1 9 0.1394845452825308 0.8890672676321991 |
| Signaling by fgfr3 1 9 0.1394845452825308 0.8890672676321991 |
| Signaling by fgfr1 1 9 0.1394845452825308 0.8890672676321991 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 17 41 0.1391158357509132 0.8893586147867545 |
| Eukaryotic translation elongation 20 77 0.1374681723877812 0.8906607486315494 |
| Ephb mediated forward signaling 10 19 0.1374362389521288 0.8906859882695011 |
| Muscle contraction 13 24 -0.1366341732216725 0.8913199634840385 |
| Role of lat2 ntal lab on calcium mobilization 1 2 -0.1362920950492382 0.8915903728103562 |
| Growth hormone receptor signaling 1 5 -0.1351698597628574 0.89247757678276 |
| Translation of replicase and assembly of the replication transcription complex 1 4 0.1337710690152315 0.8935836051221435 |
| Regulated necrosis 3 16 0.1334367139469318 0.8938480114789098 |
| Caspase activation via death receptors in the presence of ligand 0 3 0.1323347645629929 0.8947195110260895 |
| Regulation by c flip 0 3 0.1323347645629929 0.8947195110260895 |
| Translation 71 226 0.1310691426711609 0.895720611125707 |
| Serine biosynthesis 1 2 0.1306467489293949 0.8960547593418484 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0 2 0.1292960290128834 0.8971234134495409 |
| Er quality control compartment erqc 1 1 -0.1289252492407773 0.8974167973944329 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 2 2 -0.1274458816028437 0.8985875040116849 |
| Dual incision in tc ner 11 37 0.1274273498542127 0.8986021706293648 |
| Transcriptional regulation by e2f6 0 12 0.1269365952663931 0.8989905820701249 |
| Regulation of tp53 activity through acetylation 5 12 0.1269068815853019 0.8990140999661902 |
| Mtorc1 mediated signalling 4 11 0.1267593945966649 0.8991308348348197 |
| Dna double strand break response 3 21 0.1255879672499231 0.9000580882791633 |
| Josephin domain dubs 2 2 -0.124951224560335 0.9005621647719069 |
| Pten regulation 12 66 0.1246366600733971 0.9008112041378948 |
| Sars cov infections 11 60 0.1241765640695123 0.9011754777649496 |
| Metabolism of polyamines 7 41 0.1239923544836523 0.901321328586977 |
| Rho gtpases activate cit 6 11 -0.1238072506511062 0.9014678907984556 |
| Fructose metabolism 0 2 0.1235421783876604 0.9016777765637723 |
| Amino acids regulate mtorc1 3 13 0.1229693779991542 0.9021313467096892 |
| Ptk6 expression 1 1 -0.1226517754512026 0.9023828530442132 |
| Metabolism of amino acids and derivatives 46 195 0.1220478667132367 0.9028611094409178 |
| Fgfr2 alternative splicing 5 17 0.1217529793597062 0.9030946538430824 |
| Response of eif2ak4 gcn2 to amino acid deficiency 19 77 0.1217427660710027 0.903102742697057 |
| Plasma lipoprotein assembly 2 2 -0.1210084373447682 0.903684352273131 |
| Slbp dependent processing of replication dependent histone pre mrnas 4 4 -0.1181554414351872 0.9059444951506936 |
| Metabolism of lipids 42 176 0.1180507367677734 0.9060274567774697 |
| Protein methylation 1 7 -0.1173785104494923 0.906560112520216 |
| Transcriptional regulation of granulopoiesis 2 6 0.1170228165047378 0.9068419727473898 |
| Golgi to er retrograde transport 9 68 0.116936119613948 0.9069106751774396 |
| Transport of small molecules 35 139 0.1159047474545963 0.9077280331331146 |
| Rrna processing 47 173 0.1156517303059253 0.9079285630831172 |
| Mapk1 erk2 activation 1 3 -0.1151191508668659 0.9083506806220514 |
| Neutrophil degranulation 43 171 0.1150705088558809 0.9083892351218076 |
| Opioid signalling 3 23 -0.1146499109778428 0.9087226172700582 |
| Clec7a dectin 1 induces nfat activation 1 2 0.1142564316956241 0.9090345187265148 |
| Diseases of immune system 2 2 -0.114252706609743 0.9090374715785678 |
| Antigen processing cross presentation 8 49 0.1136735035421739 0.9094966174563904 |
| Apc c cdc20 mediated degradation of cyclin b 4 11 0.1130958816023584 0.9099545400501992 |
| Deubiquitination 20 93 0.1127585503628382 0.9102219807125718 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 15 52 0.1124326425973251 0.9104803743561044 |
| Mhc class ii antigen presentation 8 55 0.1122567506704308 0.9106198329494556 |
| Transcriptional regulation by ventx 3 13 -0.1115270774996344 0.9111983947951332 |
| Intra golgi and retrograde golgi to er traffic 12 79 0.1107566913069435 0.9118092893105618 |
| Tryptophan catabolism 0 2 0.1100495405084514 0.9123700858356802 |
| Mecp2 regulates neuronal receptors and channels 2 8 -0.1087507490671157 0.9134001885847298 |
| Fgfr2 mutant receptor activation 2 10 0.1086036206863918 0.9135168888514846 |
| Signaling by fgfr2 iiia tm 2 10 0.1086036206863918 0.9135168888514846 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 3 4 0.1084856317687086 0.9136104774327448 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 1 4 0.1083727045014371 0.9137000522446734 |
| Apc cdc20 mediated degradation of nek2a 3 12 -0.1078149256665328 0.914142502937106 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 3 12 -0.1078149256665328 0.914142502937106 |
| Meiotic recombination 3 12 -0.107742921741384 0.914199621041576 |
| Asparagine n linked glycosylation 22 117 0.1076554508863967 0.914269009097072 |
| Signaling by robo receptors 30 142 0.1066470154443828 0.9150690183178404 |
| Signaling by nuclear receptors 19 58 0.105598345243479 0.9159010377159396 |
| Transport to the golgi and subsequent modification 11 77 0.1054274977807282 0.916036597572086 |
| Ldl clearance 2 9 0.1052696828846259 0.9161618188362944 |
| Downstream signaling events of b cell receptor bcr 8 45 0.1051864070030004 0.9162278965247292 |
| Signaling by ntrk2 trkb 2 7 0.1046241907603864 0.9166740185985492 |
| Synthesis of pips at the plasma membrane 0 12 0.1044179743681599 0.9168376591695472 |
| Cellular response to starvation 23 90 0.1036714297439536 0.917430100215448 |
| Cross presentation of soluble exogenous antigens endosomes 6 38 0.1029988849364789 0.9179638559395564 |
| Degradation of axin 6 38 0.1029988849364789 0.9179638559395564 |
| Regulation of ras by gaps 17 42 0.1022852681602178 0.9185302482798215 |
| Transcriptional regulation by runx3 7 46 0.1022519117032303 0.9185567240658764 |
| Influenza infection 28 126 0.1020047129966743 0.9187529341694172 |
| Regulation of expression of slits and robos 26 125 0.101718620237634 0.91898002199397 |
| Egfr downregulation 0 6 0.1012713740710716 0.9193350395255916 |
| Ubiquinol biosynthesis 1 2 -0.1010735176776477 0.9194921002005902 |
| Hemostasis 27 120 0.1008247587100589 0.919689572379186 |
| Rho gtpases activate formins 9 61 0.09983531794439 0.9204750684448956 |
| Copi dependent golgi to er retrograde traffic 4 46 0.0988923388667794 0.9212237517876832 |
| Anti inflammatory response favouring leishmania parasite infection 8 17 0.0985604221779076 0.9214872954864616 |
| Nucleotide salvage 3 8 0.0985445171838308 0.921499924357 |
| Formyl peptide receptors bind formyl peptides and many other ligands 0 2 0.0982652608171505 0.9217216624934176 |
| Signaling by interleukins 16 108 0.0967940030088793 0.9228899864783306 |
| Resolution of abasic sites ap sites 7 30 0.0967215538959962 0.9229475225472932 |
| Chromatin modifying enzymes 12 71 0.0957190068547017 0.9237437449257516 |
| Recognition and association of dna glycosylase with site containing an affected purine 1 4 -0.0953565956009114 0.9240315906144444 |
| Mapk family signaling cascades 17 98 0.095295554427032 0.924080073639364 |
| Signaling by fgfr in disease 7 20 -0.0952340839872831 0.9241288979012487 |
| Nonsense mediated decay nmd 19 86 0.0952120586130722 0.924146392113411 |
| Eukaryotic translation initiation 28 101 0.0950414621774002 0.9242818939016848 |
| Degradation of beta catenin by the destruction complex 20 51 0.0950337665361361 0.924288006467807 |
| Negative regulation of flt3 1 2 0.0950072595820101 0.9243090606941587 |
| Er to golgi anterograde transport 10 76 0.094928327078846 0.9243717563589496 |
| Cellular response to chemical stress 7 78 0.0948705235406443 0.9244176696979612 |
| Trna aminoacylation 6 38 0.093963417296333 0.9251382168902392 |
| Suppression of phagosomal maturation 0 7 0.093916496461951 0.9251754894762232 |
| P75 ntr receptor mediated signalling 3 14 -0.0931298839169624 0.9258003766656258 |
| Copii mediated vesicle transport 9 32 0.0930678379681457 0.9258496680924948 |
| Selenoamino acid metabolism 20 91 0.0927330864470549 0.9261156110720714 |
| Telomere maintenance 13 43 0.092189964335622 0.9265471113893932 |
| Dna replication 34 90 0.0916459840977411 0.9269793151291652 |
| Signaling by wnt 33 90 0.0915746934517253 0.9270359586464804 |
| Pyrimidine salvage 0 2 0.0913477584090784 0.9272162708636408 |
| Hedgehog ligand biogenesis 6 40 0.091057307648458 0.9274470552208748 |
| Degradation of dvl 6 40 0.0907652293974869 0.927679138893289 |
| Cellular response to hypoxia 7 43 0.0906632653258891 0.9277601603989634 |
| Mitotic g1 phase and g1 s transition 30 79 0.0906406191772217 0.927778155320131 |
| P130cas linkage to mapk signaling for integrins 2 3 -0.0904329554374346 0.9279431693214109 |
| Synthesis of dna 31 86 0.0904136476110982 0.92795851188629 |
| G2 m checkpoints 9 83 0.0903863125829135 0.9279802331469008 |
| Mrna capping 1 15 0.0900970298955679 0.928210109422318 |
| Ub specific processing proteases 12 74 0.0898617599583053 0.9283970692976552 |
| Gluconeogenesis 1 20 -0.0898378760567709 0.9284160491271258 |
| Purine salvage 5 6 0.0891290314470664 0.9289793654465526 |
| Phosphorylation of the apc c 1 12 0.089106906335635 0.9289969487690684 |
| Orc1 removal from chromatin 19 52 0.0888402928260389 0.9292088352309018 |
| Chromosome maintenance 14 48 0.0886657039422035 0.9293475894380074 |
| Asymmetric localization of pcp proteins 6 39 0.0886457616513164 0.9293634386752364 |
| Dap12 interactions 2 5 -0.0885812492128108 0.9294147104561294 |
| Hedgehog off state 11 53 0.0885479253579396 0.9294411949733724 |
| Dectin 1 mediated noncanonical nf kb signaling 18 43 0.0884140191374346 0.9295476192711444 |
| Enos activation 2 4 0.0880735112544009 0.9298182495049272 |
| Degradation of gli1 by the proteasome 17 43 0.0879417776932618 0.9299229514170302 |
| Dna replication pre initiation 23 63 0.0876588213773034 0.9301478493623392 |
| Signaling by kit in disease 2 7 -0.0875766606711037 0.9302131529759796 |
| Arachidonate production from dag 1 2 -0.0873064898340387 0.9304278955796256 |
| Transcriptional regulation by runx1 13 69 0.0872838756825943 0.9304458704430104 |
| Trna processing 18 70 0.0864760340042909 0.9310880067862052 |
| Runx1 regulates transcription of genes involved in differentiation of myeloid cells 1 2 -0.0864691940111467 0.93109344394487 |
| Signaling by vegf 5 33 -0.0863031176359069 0.9312254602101232 |
| Stabilization of p53 6 40 0.0853828948725718 0.9319569914135086 |
| Cytosolic iron sulfur cluster assembly 1 8 -0.0850751089940208 0.9322016786951416 |
| Switching of origins to a post replicative state 22 61 0.084177008001372 0.9329156982538064 |
| Tcf dependent signaling in response to wnt 22 62 0.0838257061179442 0.9331950094192902 |
| Apc c mediated degradation of cell cycle proteins 23 59 0.0833639312648074 0.9335621673311656 |
| G1 s dna damage checkpoints 16 42 0.0833292457318501 0.9335897464246368 |
| Beta catenin independent wnt signaling 9 59 0.0832441524029302 0.9336574060043354 |
| Tnfr2 non canonical nf kb pathway 18 44 0.0823494179485097 0.934368857992626 |
| Toll like receptor cascades 1 25 0.082276072513088 0.934427181266684 |
| Clec7a dectin 1 signaling 20 50 0.0822149718469761 0.9344757679385742 |
| Signaling by the b cell receptor bcr 20 49 0.0816486891812828 0.9349260821490246 |
| Signaling by braf and raf1 fusions 5 26 0.081631171215061 0.93494001296139 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 7 51 0.0808876033715221 0.9355313387356808 |
| Caspase activation via dependence receptors in the absence of ligand 1 2 -0.0799817468700849 0.9362517733432074 |
| Unwinding of dna 8 8 -0.0799467366159256 0.9362796183177248 |
| Interleukin 1 signaling 6 47 0.0798475455104134 0.9363585091651154 |
| Fceri mediated nf kb activation 6 45 0.079621611776633 0.9365382060730176 |
| Kinesins 6 18 -0.07933415477091 0.9367668403265734 |
| Signaling by tgf beta receptor complex 4 21 -0.078478979299171 0.9374470507332529 |
| Mapk3 erk1 activation 0 3 0.0762600723961778 0.9392121909148874 |
| Glyoxylate metabolism and glycine degradation 7 12 0.076157544031938 0.9392937595031652 |
| Eph ephrin mediated repulsion of cells 2 13 -0.0750812086284963 0.9401500989603876 |
| Mtor signalling 5 15 0.075054367005959 0.9401714552186426 |
| Bile acid and bile salt metabolism 1 5 0.0740803268856539 0.9409464691130816 |
| Synthesis of bile acids and bile salts 1 5 0.0740803268856539 0.9409464691130816 |
| Cyclin d associated events in g1 5 13 0.0720971960872408 0.9425245576187034 |
| Signaling by moderate kinase activity braf mutants 3 17 0.0719973099624795 0.9426040486362416 |
| Signaling by ntrks 8 31 -0.0716406568202102 0.9428878837198836 |
| Transcription of e2f targets under negative control by dream complex 1 4 -0.0714236826782159 0.9430605616881746 |
| Polb dependent long patch base excision repair 1 7 -0.0712701922474394 0.9431827180255784 |
| Robo receptors bind akap5 0 2 0.0709904181983829 0.9434053814210336 |
| Stat3 nuclear events downstream of alk signaling 1 4 0.0709021330416757 0.9434756457285216 |
| Pyruvate metabolism 3 15 0.0704304154641703 0.943851083310412 |
| Fbxw7 mutants and notch1 in cancer 2 3 0.0697679774733535 0.9443783353223184 |
| Sumoylation 21 81 -0.0660384721442857 0.9473471959489546 |
| Frs mediated fgfr4 signaling 1 3 -0.0650858137813625 0.9481056754447674 |
| Frs mediated fgfr2 signaling 1 3 -0.0650858137813625 0.9481056754447674 |
| Activated ntrk2 signals through frs2 and frs3 1 3 -0.0650858137813625 0.9481056754447674 |
| Tie2 signaling 1 3 -0.0650858137813625 0.9481056754447674 |
| Frs mediated fgfr3 signaling 1 3 -0.0650858137813625 0.9481056754447674 |
| Frs mediated fgfr1 signaling 1 3 -0.0650858137813625 0.9481056754447674 |
| Signaling by flt3 itd and tkd mutants 1 3 -0.0650858137813625 0.9481056754447674 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 1 2 0.0648814165128116 0.9482684168883136 |
| Phase 0 rapid depolarisation 1 2 0.0648814165128116 0.9482684168883136 |
| Small interfering rna sirna biogenesis 2 4 -0.0645806536783581 0.9485078886773703 |
| Endosomal sorting complex required for transport escrt 2 8 0.0645211898738254 0.9485552351838784 |
| Map2k and mapk activation 4 15 0.0641228444326458 0.9488724120486514 |
| Cargo recognition for clathrin mediated endocytosis 5 32 -0.0626976356277754 0.950007280186992 |
| Translesion synthesis by polh 5 12 0.0626260871086053 0.9500642556785136 |
| Processing of capped intronless pre mrna 7 16 -0.0621970859878581 0.9504058830438612 |
| Adherens junctions interactions 1 7 0.061912852949914 0.9506322319615336 |
| Dna replication initiation 3 8 -0.0607022343942849 0.9515963521754156 |
| Extension of telomeres 5 33 -0.0604975530543988 0.9517593646619242 |
| Cyclin a b1 b2 associated events during g2 m transition 3 12 0.0600181409993017 0.9521411863069174 |
| Interferon alpha beta signaling 0 9 0.0586759281234397 0.9532102328704236 |
| Recognition of dna damage by pcna containing replication complex 5 25 0.0580176257590207 0.9537345888491288 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 1 4 -0.0575113458321379 0.9541378684017024 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 1 7 0.0567005455925848 0.954783739396617 |
| Ripk1 mediated regulated necrosis 1 10 0.0561638040831307 0.9552113157848794 |
| Signaling by fgfr4 in disease 2 3 -0.0559301731107555 0.9553974337775925 |
| Formation of the early elongation complex 5 18 0.0546918767630508 0.9563839410818936 |
| Tbc rabgaps 7 17 0.0538505985980076 0.9570541961205888 |
| Cs ds degradation 0 2 0.0530974027187892 0.9576543008656896 |
| Pp2a mediated dephosphorylation of key metabolic factors 0 3 0.0525067067765681 0.9581249514734024 |
| Polymerase switching on the c strand of the telomere 2 17 -0.0524452931149653 0.9581738850644428 |
| Hiv transcription initiation 4 13 -0.0523986945697836 0.958211014272384 |
| Regulation of ifna signaling 2 3 0.0520631430545659 0.9584783806986212 |
| Mitochondrial iron sulfur cluster biogenesis 4 5 0.0510227757433053 0.9593073717642002 |
| Formation of incision complex in gg ner 9 16 -0.0505269384750108 0.9597024830173772 |
| Epha mediated growth cone collapse 3 11 -0.0494015859931081 0.9605992642672996 |
| Ire1alpha activates chaperones 3 21 0.0492577648666335 0.9607138773879114 |
| Rna polymerase i transcription 4 22 0.0492483858379561 0.9607213516987518 |
| Processing of intronless pre mrnas 6 14 -0.0482072430048877 0.9615510778176533 |
| Urea cycle 0 2 0.0480260625992049 0.9616954716179358 |
| Hdr through mmej alt nhej 1 8 0.0467343204918259 0.962724976423004 |
| Signaling by tgfb family members 4 22 -0.0461511633305893 0.963189766981556 |
| P75ntr regulates axonogenesis 1 3 0.0457519553171697 0.9635079527805608 |
| Protein protein interactions at synapses 2 15 0.0455266126761044 0.9636875630378596 |
| Ecm proteoglycans 0 2 0.0453180880133 0.9638537700997224 |
| Caspase mediated cleavage of cytoskeletal proteins 4 8 -0.045044764153712 0.9640716285093304 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0 3 0.044427687799073 0.9645634917610764 |
| Sars cov 1 infection 1 12 0.0439039193142567 0.9649809911541876 |
| Activation of the pre replicative complex 3 21 0.0435487201173168 0.9652641283006808 |
| Nostrin mediated enos trafficking 0 2 0.0426839383769802 0.965953483218862 |
| Programmed cell death 22 101 -0.0411894015764231 0.9671449028205616 |
| Beta oxidation of pristanoyl coa 1 3 0.04063714262338 0.967585173069658 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 1 3 0.04063714262338 0.967585173069658 |
| Neurexins and neuroligins 5 11 -0.0401999344276138 0.9679337299084518 |
| Rsk activation 1 2 0.040131713066928 0.9679881187885392 |
| Mrna editing 0 2 0.040066738509224 0.9680399193219418 |
| Activated notch1 transmits signal to the nucleus 0 2 0.0387041654155057 0.9691262523781496 |
| Pd 1 signaling 1 2 0.0385855363632997 0.9692208340156698 |
| Sumoylation of intracellular receptors 1 2 0.0371126392242893 0.9703951943281766 |
| Assembly of collagen fibrils and other multimeric structures 0 2 0.0363314076296507 0.9710181067975804 |
| Endosomal vacuolar pathway 1 2 0.0359123752185036 0.9713522282360184 |
| Trafficking and processing of endosomal tlr 0 2 0.0357122627462405 0.9715117925326048 |
| Transcriptional regulation by small rnas 7 37 -0.0352443866410389 0.9718848687783272 |
| Nuclear events kinase and transcription factor activation 4 10 -0.0339891750658903 0.972885782760933 |
| Microrna mirna biogenesis 2 11 0.0309578612487582 0.9753031454034772 |
| Senescence associated secretory phenotype sasp 4 17 -0.0303209373164781 0.9758110986845424 |
| Trafficking of ampa receptors 10 11 0.0299760671584137 0.9760861402323158 |
| Interferon gamma signaling 6 14 0.0273320180258067 0.9781949197104084 |
| Synthesis of ip3 and ip4 in the cytosol 4 4 -0.0264863045625123 0.9788694571440476 |
| Golgi cisternae pericentriolar stack reorganization 6 11 0.0262174953166446 0.9790838614339604 |
| Processive synthesis on the lagging strand 3 14 -0.0255565812481349 0.9796110178920698 |
| Peptide hormone metabolism 11 12 0.0249925813705709 0.9800608809704924 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 7 16 -0.0232928828554376 0.98141664883377 |
| Toll like receptor tlr1 tlr2 cascade 3 16 -0.0231510119716927 0.9815298149044268 |
| Rhot1 gtpase cycle 1 2 -0.0226292656577222 0.9819459991823614 |
| Gap filling dna repair synthesis and ligation in gg ner 3 20 -0.0220733869669727 0.9823894154265074 |
| Negative regulation of notch4 signaling 4 42 -0.0220322394188024 0.9824222384375834 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 3 11 -0.0214245946715948 0.9829069543558362 |
| Transcription of the hiv genome 9 29 -0.021369346845042 0.9829510256539112 |
| Nuclear events stimulated by alk signaling in cancer 5 12 -0.0213606912556706 0.982957930239008 |
| Nonhomologous end joining nhej 7 18 -0.0201554584372673 0.9839193596776388 |
| Negative regulators of ddx58 ifih1 signaling 3 9 -0.0200558045100479 0.983998855938292 |
| Nuclear envelope ne reassembly 10 49 -0.0188955495506998 0.9849244298523812 |
| Metabolism of nitric oxide nos3 activation and regulation 2 7 0.0183705543392122 0.9853432427110538 |
| Other interleukin signaling 1 4 -0.0170458973670844 0.9864000002775476 |
| Rrna modification in the mitochondrion 4 4 -0.0170205967779871 0.9864201842987445 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 5 11 -0.0168111175022646 0.9865873006667768 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 4 9 -0.0162005047011496 0.9870744328237476 |
| Synthesis of pips at the er membrane 2 3 -0.015880101963556 0.987330044334791 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 3 5 -0.0151740858155277 0.9878932958058608 |
| Apobec3g mediated resistance to hiv 1 infection 2 2 -0.0147253778941538 0.988251272920442 |
| Regulation of mrna stability by proteins that bind au rich elements 21 65 -0.0142088229012344 0.9886633810407648 |
| Inhibition of dna recombination at telomere 5 12 -0.011903040459978 0.9905029720511428 |
| Interaction between l1 and ankyrins 2 3 -0.0105730159728897 0.9915641109672 |
| Factors involved in megakaryocyte development and platelet production 9 43 -0.0105673771375917 0.99156860985549 |
| Signaling by scf kit 2 12 -0.0105631011805064 0.9915720213852208 |
| Regulation of tp53 expression and degradation 9 9 -0.0066481861505468 0.9946955539878166 |
| Rna polymerase i promoter escape 1 13 -0.0063428411877408 0.994939178878884 |
| Interferon signaling 16 67 -0.0062444775722864 0.9950176601346256 |
| Base excision repair 4 33 -0.0057156686170677 0.99543958108641 |
| Mitotic spindle checkpoint 14 56 -0.0021883329244312 0.9982539643392694 |
| Lagging strand synthesis 3 19 -0.0009004656941919 0.9992815324221652 |
| Chl1 interactions 2 3 -0.0008586662478117 0.9993148835421788 |
| Ptk6 regulates proteins involved in rna processing 2 2 -0.000418919886507 0.9996657503001192 |
| Surfactant metabolism 1 2 0.0 1.0 |
| Erbb2 regulates cell motility 1 2 0.0 1.0 |
| Defective cftr causes cystic fibrosis 4 42 0.0 1.0 |
| Mapk6 mapk4 signaling 5 50 0.0 1.0 |
| Dual incision in gg ner 9 27 0.0 1.0 |
| Potential therapeutics for sars 8 40 0.0 1.0 |
| Negative regulation of the pi3k akt network 3 14 0.0 1.0 |
| Mitotic metaphase and anaphase 28 139 0.0 1.0 |
| Membrane trafficking 72 234 0.0 1.0 |
| Dna damage recognition in gg ner 8 19 0.0 1.0 |
| Nervous system development 45 221 0.0 1.0 |
| Transcription coupled nucleotide excision repair tc ner 13 50 0.0 1.0 |
| Nucleotide excision repair 18 59 0.0 1.0 |
| Global genome nucleotide excision repair gg ner 15 45 0.0 1.0 |
| Formation of tc ner pre incision complex 9 29 0.0 1.0 |
| Inactivation of cdc42 and rac1 3 3 0.0 1.0 |
| Diseases of mitotic cell cycle 6 16 0.0 1.0 |
| Rnd1 gtpase cycle 3 12 0.0 1.0 |
| Proton coupled monocarboxylate transport 1 2 0.0 1.0 |
| Mitotic g2 g2 m phases 27 91 0.0 1.0 |
| Snrnp assembly 10 42 0.0 1.0 |
| Class i mhc mediated antigen processing presentation 34 123 0.0 1.0 |
| Antigen processing ubiquitination proteasome degradation 31 102 0.0 1.0 |
| Positive epigenetic regulation of rrna expression 11 27 0.0 1.0 |
| Signaling by hedgehog 5 59 0.0 1.0 |
| Regulation of beta cell development 1 2 0.0 1.0 |
| Auf1 hnrnp d0 binds and destabilizes mrna 14 43 0.0 1.0 |
| Erythropoietin activates phospholipase c gamma plcg 1 2 0.0 1.0 |
| Notch4 intracellular domain regulates transcription 1 2 0.0 1.0 |
| Organelle biogenesis and maintenance 15 91 0.0 1.0 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 6 22 0.0 1.0 |
| Signaling by rho gtpases miro gtpases and rhobtb3 73 258 0.0 1.0 |
| Rho gtpase effectors 31 118 0.0 1.0 |
| Abc transporter disorders 4 42 0.0 1.0 |
| Disorders of transmembrane transporters 14 74 0.0 1.0 |
| C type lectin receptors clrs 5 55 0.0 1.0 |
| Diseases of signal transduction by growth factor receptors and second messengers 49 149 0.0 1.0 |
| Termination of translesion dna synthesis 6 19 0.0 1.0 |
| Signaling by fgfr2 in disease 4 13 0.0 1.0 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 3 24 0.0 1.0 |
| Shc mediated cascade fgfr4 1 2 0.0 1.0 |
| Grb2 events in erbb2 signaling 1 2 0.0 1.0 |
| Signaling by notch4 4 44 0.0 1.0 |
| Shc mediated cascade fgfr3 1 2 0.0 1.0 |
| Chondroitin sulfate dermatan sulfate metabolism 1 3 0.0 1.0 |
| Vesicle mediated transport 75 240 0.0 1.0 |
| Pcna dependent long patch base excision repair 3 20 0.0 1.0 |
| Interleukin 1 family signaling 14 51 0.0 1.0 |
| Hedgehog on state 15 45 0.0 1.0 |
| Shc1 events in egfr signaling 1 2 0.0 1.0 |
| Shc mediated cascade fgfr1 1 2 0.0 1.0 |
| Telomere extension by telomerase 4 12 0.0 1.0 |
| Transcriptional regulation by tp53 36 125 0.0 1.0 |
| Transport of bile salts and organic acids metal ions and amine compounds 1 2 0.0 1.0 |
| The role of nef in hiv 1 replication and disease pathogenesis 5 13 0.0 1.0 |
| Nef and signal transduction 2 2 0.0 1.0 |
| Pcp ce pathway 5 52 0.0 1.0 |
| Cell cycle 65 305 0.0 1.0 |
| Ngf stimulated transcription 2 3 0.0 1.0 |
| Host interactions of hiv factors 26 97 0.0 1.0 |
| Hiv infection 34 135 0.0 1.0 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 1 2 0.0 1.0 |
| Rho gtpase cycle 37 162 0.0 1.0 |
| Signaling by fgfr3 fusions in cancer 1 2 0.0 1.0 |
| Clathrin mediated endocytosis 7 56 0.0 1.0 |
| Signaling by receptor tyrosine kinases 27 119 0.0 1.0 |
| Signaling by tgf beta receptor complex in cancer 1 2 0.0 1.0 |
| Intracellular signaling by second messengers 23 94 0.0 1.0 |
| Hiv life cycle 21 76 0.0 1.0 |
| Egfr transactivation by gastrin 1 2 0.0 1.0 |
| Shc1 events in erbb4 signaling 1 2 0.0 1.0 |
| Activated ntrk3 signals through ras 1 2 0.0 1.0 |
| Adaptive immune system 50 199 0.0 1.0 |
| Costimulation by the cd28 family 2 15 0.0 1.0 |
| Nucleotide biosynthesis 13 13 0.0 1.0 |
| Cytokine signaling in immune system 50 181 0.0 1.0 |
| Cellular responses to stimuli 66 329 0.0 1.0 |
| Sema4d mediated inhibition of cell attachment and migration 1 3 0.0 1.0 |
| Metabolism of rna 100 478 0.0 1.0 |
| Neddylation 22 85 0.0 1.0 |
| Gene silencing by rna 12 45 0.0 1.0 |
| Association of tric cct with target proteins during biosynthesis 16 16 0.0 1.0 |
| Runx3 regulates notch signaling 1 2 0.0 1.0 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 1 2 0.0 1.0 |
| Signaling by notch 5 58 0.0 1.0 |
| Developmental biology 76 275 0.0 1.0 |
| Sirt1 negatively regulates rrna expression 1 3 0.0 1.0 |
| Platelet adhesion to exposed collagen 1 2 0.0 1.0 |
| Dna repair 37 120 0.0 1.0 |
| Mitotic prometaphase 23 88 0.0 1.0 |
| M phase 47 191 0.0 1.0 |
| Glutamate and glutamine metabolism 3 9 0.0 1.0 |
| Dna strand elongation 3 27 0.0 1.0 |
| S phase 20 97 0.0 1.0 |
| Cell cycle mitotic 55 254 0.0 1.0 |
| Resolution of sister chromatid cohesion 14 61 0.0 1.0 |
| Activated ntrk2 signals through ras 1 2 0.0 1.0 |
| Cell cycle checkpoints 28 140 0.0 1.0 |
| Sumo is conjugated to e1 uba2 sae1 2 2 0.0 1.0 |
| Glycolysis 9 49 0.0 1.0 |
| Sumo is transferred from e1 to e2 ube2i ubc9 2 2 0.0 1.0 |
| Glucose metabolism 11 60 0.0 1.0 |
| Separation of sister chromatids 20 106 0.0 1.0 |
| Tcr signaling 15 49 0.0 1.0 |
| Processing and activation of sumo 2 2 0.0 1.0 |
| Diseases associated with glycosaminoglycan metabolism 1 4 0.0 1.0 |
| Dna damage bypass 9 30 0.0 1.0 |
| Rna polymerase ii transcription 97 321 0.0 1.0 |
| Postmitotic nuclear pore complex npc reformation 5 24 0.0 1.0 |
| Rna polymerase i transcription initiation 4 20 0.0 1.0 |
| Hiv transcription elongation 8 26 0.0 1.0 |
| Disinhibition of snare formation 3 3 0.0 1.0 |
| Synthesis of pips at the late endosome membrane 2 3 0.0 1.0 |
| Processing of capped intron containing pre mrna 51 179 0.0 1.0 |
| Mrna splicing 39 138 0.0 1.0 |
| Mrna splicing minor pathway 11 33 0.0 1.0 |
| Sos mediated signalling 1 2 0.0 1.0 |
| Hiv elongation arrest and recovery 7 21 0.0 1.0 |
| Fc epsilon receptor fceri signaling 14 54 0.0 1.0 |
| Metabolism of carbohydrates 17 96 0.0 1.0 |
| Shc related events triggered by igf1r 1 2 0.0 1.0 |
| Estrogen dependent gene expression 7 29 0.0 1.0 |
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