| term overlap setsize score pval |
| Regulation of expression of slits and robos 39 155 7.018593644354294 6.2032314890160574e-18 |
| Signaling by robo receptors 43 197 5.856885971171685 3.6613963410436e-17 |
| Eukaryotic translation elongation 28 89 9.411789326822465 6.078852394225761e-16 |
| Selenoamino acid metabolism 29 107 7.626154939587775 1.485857254794931e-14 |
| Metabolism of amino acids and derivatives 47 281 4.214831239221483 6.174502252615192e-14 |
| Srp dependent cotranslational protein targeting to membrane 28 108 7.162340425531915 1.4500777949501825e-13 |
| Response of eif2ak4 gcn2 to amino acid deficiency 26 94 7.8009720837487535 2.085135300625772e-13 |
| Eukaryotic translation initiation 28 116 6.505802707930368 9.93731548037032e-13 |
| Nervous system development 59 443 3.259811598329537 1.0515076673430436e-12 |
| Nonsense mediated decay nmd 27 110 6.640702939145116 1.6583528152950797e-12 |
| Synthesis of dna 26 117 5.815375302663438 4.870344594458929e-11 |
| Dna replication 28 137 5.240913527230139 7.209804461848855e-11 |
| Cellular response to starvation 28 139 5.14540923902626 1.0335258215338741e-10 |
| Infectious disease 67 619 2.575666633040788 3.7695025364560665e-10 |
| Metabolism of rna 69 647 2.537808212548697 3.8186473827168726e-10 |
| Influenza infection 28 150 4.676107429368678 6.62404912690743e-10 |
| Translation 39 289 3.2110849673202613 6.309464957319068e-09 |
| Rrna processing 31 202 3.6983232528144057 1.1538508148781031e-08 |
| Regulation of runx2 expression and activity 16 61 7.120700783771323 2.1775668041885444e-08 |
| Cellular responses to stimuli 62 614 2.356119531977131 2.707583462768365e-08 |
| S phase 26 158 3.991974833076528 4.2032624566333054e-08 |
| Orc1 removal from chromatin 16 65 6.536709289524938 5.802988240811716e-08 |
| Regulation of hmox1 expression and activity 15 58 6.9731330348114975 7.409906562831398e-08 |
| Scf skp2 mediated degradation of p27 p21 14 54 6.984090909090909 1.958728795142328e-07 |
| Developmental biology 63 665 2.1882919005613477 2.196470180038712e-07 |
| Negative regulation of notch4 signaling 13 49 7.193928980526919 4.010944532638898e-07 |
| Dna replication pre initiation 18 92 4.877027027027027 3.738854751759238e-07 |
| Mitotic g1 phase and g1 s transition 23 143 3.86480701754386 3.9053480972228026e-07 |
| Switching of origins to a post replicative state 17 85 5.005197505197505 5.683452853189682e-07 |
| The role of gtse1 in g2 m progression after g2 checkpoint 15 67 5.760869565217392 5.731187040525312e-07 |
| Regulation of runx3 expression and activity 13 52 6.638487972508592 8.475999138252711e-07 |
| Degradation of gli1 by the proteasome 13 53 6.471855670103093 1.0737385531489151e-06 |
| Dectin 1 mediated noncanonical nf kb signaling 13 53 6.471855670103093 1.0737385531489151e-06 |
| Transcriptional regulation by runx2 18 100 4.397560975609756 1.3567529798580167e-06 |
| Apc c mediated degradation of cell cycle proteins 16 81 4.919502074688797 1.4564224351240163e-06 |
| Separation of sister chromatids 25 179 3.275582768183191 1.870218183583877e-06 |
| Metabolism of polyamines 12 48 6.626886145404664 2.2472626107199536e-06 |
| Regulation of ras by gaps 13 57 5.881068416119962 2.6107945430376755e-06 |
| Cross presentation of soluble exogenous antigens endosomes 11 41 7.279123887748118 2.8096846078232e-06 |
| Tnfr2 non canonical nf kb pathway 13 58 5.7497823596792665 3.217371004058704e-06 |
| Hedgehog off state 17 96 4.303350088160215 3.366782997689541e-06 |
| Degradation of dvl 12 50 6.276803118908382 3.5811219843818797e-06 |
| Degradation of beta catenin by the destruction complex 15 77 4.8266880384692445 3.721831864949173e-06 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 13 59 5.624204392649037 3.945596255592977e-06 |
| G1 s dna damage checkpoints 13 61 5.388745704467354 5.851975216805117e-06 |
| G2 m checkpoints 20 134 3.517580562284372 7.285631062332128e-06 |
| Cell cycle checkpoints 30 257 2.674517112843104 7.855606095136968e-06 |
| Lagging strand synthesis 8 23 10.539319727891156 7.832237274035295e-06 |
| Metabolism of nucleotides 15 82 4.464169834059516 8.391365531545643e-06 |
| Cdt1 association with the cdc6 orc origin complex 12 54 5.676660787771899 8.463205997617652e-06 |
| Cell cycle mitotic 47 498 2.136710242329192 9.495364525322406e-06 |
| Degradation of axin 11 48 5.89771907431045 1.4724035658487924e-05 |
| Auf1 hnrnp d0 binds and destabilizes mrna 11 48 5.89771907431045 1.4724035658487924e-05 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 13 68 4.699493908153702 2.043120370616848e-05 |
| Cellular response to hypoxia 12 59 5.070133963750985 2.2100791839153253e-05 |
| Cyclin a cdk2 associated events at s phase entry 14 79 4.2867768595041325 2.436728238140036e-05 |
| Stabilization of p53 11 51 5.453696098562628 2.716916132128684e-05 |
| Cell cycle 53 613 1.9434751203852327 3.044965364017848e-05 |
| Downstream signaling events of b cell receptor bcr 13 71 4.4550302168503375 3.309114694707672e-05 |
| Signaling by notch4 13 71 4.4550302168503375 3.309114694707672e-05 |
| Dna strand elongation 9 35 6.846625766871166 3.325402935479346e-05 |
| Mitotic metaphase and anaphase 26 225 2.629396984924623 3.773917242885339e-05 |
| Hedgehog ligand biogenesis 11 53 5.192920700107559 3.9795614260859775e-05 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 8 28 7.900408163265306 3.998190987032918e-05 |
| Regulation of pten stability and activity 12 63 4.670539820866618 4.408263244019786e-05 |
| Asymmetric localization of pcp proteins 11 54 5.0716298171052 4.781088149168462e-05 |
| Defective cftr causes cystic fibrosis 11 54 5.0716298171052 4.781088149168462e-05 |
| Innate immune system 53 624 1.9037407268934847 4.926876168284919e-05 |
| Clec7a dectin 1 signaling 14 85 3.9220696077290182 5.684534787901179e-05 |
| Polymerase switching 6 16 11.814634146341463 6.933879980949677e-05 |
| Recognition of dna damage by pcna containing replication complex 8 30 7.180705009276438 6.905548578182881e-05 |
| Antigen processing cross presentation 13 77 4.03485824742268 8.003098382958229e-05 |
| Signaling by hedgehog 17 122 3.229007029007029 8.548370027532153e-05 |
| Neddylation 22 185 2.7036397381038304 9.668366347627172e-05 |
| Fceri mediated nf kb activation 12 68 4.251322751322752 9.63103017941205e-05 |
| Apoptosis 20 159 2.877396827308028 9.141758095091533e-05 |
| Pcp ce pathway 13 78 3.9723711340206185 9.184317617705106e-05 |
| Copi mediated anterograde transport 14 89 3.711349862258954 9.544684749843776e-05 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 12 68 4.251322751322752 9.63103017941205e-05 |
| Processive synthesis on the lagging strand 6 17 10.739467849223947 0.0001027627770781 |
| Pcna dependent long patch base excision repair 7 24 8.11872529052354 0.0001063915357976 |
| Uch proteinases 13 79 3.911777569509528 0.0001051338825328 |
| Signaling by the b cell receptor bcr 14 91 3.61419984973704 0.0001221323205636 |
| Hedgehog on state 12 70 4.10387398893146 0.0001287423110454 |
| Post chaperonin tubulin folding pathway 6 18 9.84349593495935 0.000147824727769 |
| Abc transporter disorders 11 61 4.358439425051334 0.0001532274543384 |
| Interleukin 1 signaling 13 82 3.740534887195577 0.000155441905738 |
| Extension of telomeres 10 52 4.711163153786105 0.0001749584192087 |
| Signaling by interleukins 26 248 2.351275003817377 0.0001914962654325 |
| Interleukin 1 family signaling 14 95 3.434292419140904 0.0001953848189002 |
| Deubiquitination 24 221 2.4419456403007134 0.0001970192581635 |
| Tcr signaling 13 85 3.5835624284077894 0.0002252023491574 |
| Rho gtpases activate formins 17 133 2.919456591870385 0.0002497324937721 |
| Transcriptional regulation by runx3 13 86 3.5341053523513626 0.0002537455991208 |
| Mapk family signaling cascades 23 212 2.436168198273461 0.0002701860023103 |
| Cytoprotection by hmox1 15 110 3.1392611964694344 0.0002809135327474 |
| Mitotic g2 g2 m phases 21 186 2.54358681151134 0.0002870436143322 |
| C type lectin receptors clrs 14 100 3.23294253315395 0.0003377595891643 |
| Telomere c strand lagging strand synthesis 8 37 5.443490499648135 0.0003368638288124 |
| Transcriptional regulation by runx1 18 149 2.738645038167939 0.0003371722595291 |
| Selective autophagy 11 67 3.889043707832209 0.0003614243000186 |
| Programmed cell death 20 179 2.5101971000763137 0.0004560721449882 |
| Post translational protein modification 72 1003 1.5915644241388178 0.0004809106816785 |
| Host interactions of hiv factors 15 116 2.9509255273353423 0.0005026110809509 |
| Er to golgi anterograde transport 16 129 2.8157015385745234 0.0005298711432898 |
| Dna damage bypass 9 49 4.443865030674846 0.000525961744528 |
| Resolution of abasic sites ap sites 8 41 4.781694495980211 0.0007020518814063 |
| Dual incision in gg ner 8 42 4.640576230492197 0.0008308295163249 |
| Transport to the golgi and subsequent modification 17 148 2.581120756693276 0.000874884181909 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 7 33 5.303462321792261 0.0008961412475066 |
| Abc family proteins mediated transport 11 75 3.4000898357289526 0.0009688424330029 |
| Ctla4 inhibitory signaling 5 17 8.186274509803921 0.0010331595236533 |
| Mapk6 mapk4 signaling 11 77 3.29637234770705 0.0012104804569497 |
| Translocation of slc2a4 glut4 to the plasma membrane 10 66 3.528249414519906 0.0012648600893329 |
| Interconversion of nucleotide di and triphosphates 6 26 5.901219512195122 0.0013134629127741 |
| Copi independent golgi to er retrograde traffic 8 45 4.262989520132377 0.0013343316606639 |
| Tcf dependent signaling in response to wnt 16 142 2.5217677665810445 0.0015073525749888 |
| Regulation of mrna stability by proteins that bind au rich elements 11 79 3.1987558883923177 0.0014996341500027 |
| Cytokine signaling in immune system 33 392 1.8461496989846349 0.0015567910815276 |
| Adaptive immune system 40 504 1.7380665562415298 0.0015850149264305 |
| Beta catenin independent wnt signaling 14 117 2.694575944796598 0.0016472332548941 |
| Autophagy 15 130 2.5879017013232515 0.0016506235238191 |
| Hiv infection 21 213 2.1797038784067087 0.0016959390070549 |
| Signaling by wnt 21 213 2.1797038784067087 0.0016959390070549 |
| Diseases of signal transduction by growth factor receptors and second messengers 29 333 1.910742340926944 0.0017788434602531 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 8 47 4.043537414965987 0.0017870110754962 |
| Polymerase switching on the c strand of the telomere 6 28 5.363636363636363 0.0019782028444853 |
| Caspase mediated cleavage of cytoskeletal proteins 4 12 9.807692307692308 0.0020333503076747 |
| Activation of caspases through apoptosome mediated cleavage 3 6 19.585858585858585 0.0020735614034028 |
| Cellular response to chemical stress 15 133 2.521318033477208 0.0020734320957393 |
| Interleukin 12 signaling 7 38 4.445765718415347 0.0021434540231206 |
| M phase 30 355 1.8487179487179488 0.0023674413874624 |
| Dna double strand break repair 15 137 2.437633642195296 0.0027738494817058 |
| Ub specific processing proteases 16 151 2.3514369140925155 0.0028440298473024 |
| Activation of ampk downstream of nmdars 5 21 6.137170385395538 0.0028896459807526 |
| Telomere maintenance 10 74 3.084656762295082 0.0030409328309506 |
| Cytosolic sulfonation of small molecules 4 14 7.844534412955466 0.0038035060050311 |
| Transport of connexons to the plasma membrane 4 14 7.844534412955466 0.0038035060050311 |
| Phase ii conjugation of compounds 8 53 3.502222222222222 0.0038997222190096 |
| Membrane trafficking 40 532 1.634181844001846 0.0041605754726861 |
| Asparagine n linked glycosylation 22 245 1.963767569808192 0.0042596800383346 |
| Interleukin 12 family signaling 7 43 3.8263181715320207 0.0044352119943925 |
| Trna modification in the nucleus and cytosol 7 43 3.8263181715320207 0.0044352119943925 |
| Rho gtpase effectors 22 246 1.9547944177671068 0.0044713244672609 |
| Base excision repair 8 55 3.3524967433782025 0.0049203851055373 |
| Gap junction assembly 4 15 7.130658814869341 0.004988841333209 |
| Class i mhc mediated antigen processing presentation 25 295 1.845587659541148 0.0051082271293345 |
| Tp53 regulates transcription of caspase activators and caspases 3 8 11.74909090909091 0.0053942671417733 |
| Smac xiap regulated apoptotic response 3 8 11.74909090909091 0.0053942671417733 |
| Homology directed repair 12 106 2.5227213028631468 0.0054352061665167 |
| Aggrephagy 6 34 4.211672473867596 0.0055117318404591 |
| Termination of translesion dna synthesis 6 34 4.211672473867596 0.0055117318404591 |
| Resolution of sister chromatid cohesion 13 120 2.402601406686579 0.0056602740520244 |
| Fc epsilon receptor fceri signaling 12 108 2.469650205761317 0.0063090810737558 |
| Nucleotide biosynthesis 4 16 6.535762483130904 0.0063986173037271 |
| Regulation of tp53 activity through phosphorylation 10 82 2.739640255009108 0.0064027738457468 |
| Vesicle mediated transport 40 546 1.5865509087457066 0.0064420645233292 |
| Neutrophil degranulation 26 319 1.7681639382194714 0.0071792942897205 |
| Signaling by notch 15 152 2.167339166704448 0.00733823273079 |
| Polb dependent long patch base excision repair 3 9 9.78989898989899 0.0078003581692789 |
| Prolactin receptor signaling 3 9 9.78989898989899 0.0078003581692789 |
| Pecam1 interactions 3 9 9.78989898989899 0.0078003581692789 |
| Translesion synthesis by polk 4 17 6.032388663967612 0.0080495273899022 |
| Regulation of runx1 expression and activity 4 17 6.032388663967612 0.0080495273899022 |
| Nuclear events stimulated by alk signaling in cancer 4 17 6.032388663967612 0.0080495273899022 |
| Intraflagellar transport 7 48 3.357955392181213 0.0082199413511063 |
| Dna repair 24 291 1.7884606267482104 0.0083338851472339 |
| Chromosome maintenance 11 100 2.4386636827169323 0.009397750100963 |
| Activation of atr in response to replication stress 6 38 3.683689024390244 0.0095994200986085 |
| Disorders of transmembrane transporters 12 115 2.300131847057413 0.0102720944117582 |
| Gap filling dna repair synthesis and ligation in gg ner 5 28 4.266249228327013 0.0105347068278647 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 5 28 4.266249228327013 0.0105347068278647 |
| Gap junction trafficking and regulation 5 28 4.266249228327013 0.0105347068278647 |
| Regulation of bach1 activity 3 10 8.39047619047619 0.0107435842434709 |
| Antigen processing ubiquitination proteasome degradation 21 250 1.820411414133092 0.010782742841953 |
| Rrna modification in the nucleus and cytosol 8 63 2.862486085343228 0.0111520419891808 |
| Transport and synthesis of paps 2 4 19.548387096774192 0.0133763629296313 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 6 41 3.366898954703833 0.0138285747900004 |
| Purine ribonucleoside monophosphate biosynthesis 3 11 7.340909090909091 0.0142438301551866 |
| Apoptosis induced dna fragmentation 3 11 7.340909090909091 0.0142438301551866 |
| Processing of dna double strand break ends 8 66 2.713581984517945 0.0145727731801729 |
| Translesion synthesis by polh 4 20 4.899797570850202 0.0145952588649919 |
| Signaling by scf kit 5 31 3.7728194726166326 0.016158457458282 |
| Biological oxidations 10 94 2.345335675253708 0.0161360407428942 |
| Processive synthesis on the c strand of the telomere 4 21 4.611097880447725 0.0173495207202435 |
| Formation of tubulin folding intermediates by cct tric 4 21 4.611097880447725 0.0173495207202435 |
| Activation of the pre replicative complex 5 33 3.502607939727615 0.0208457080812305 |
| Nade modulates death signalling 2 5 13.030913978494624 0.0215767580713982 |
| Fcgr activation 2 5 13.030913978494624 0.0215767580713982 |
| Netrin mediated repulsion signals 2 5 13.030913978494624 0.0215767580713982 |
| Cyclin d associated events in g1 6 45 3.0203252032520327 0.0212819442655169 |
| Fbxw7 mutants and notch1 in cancer 2 5 13.030913978494624 0.0215767580713982 |
| Pten regulation 12 128 2.0395913154533845 0.0224426033326037 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 3 13 5.871515151515151 0.022960782690956 |
| Cytochrome c mediated apoptotic response 3 13 5.871515151515151 0.022960782690956 |
| Downstream signal transduction 4 23 4.124866822927765 0.0237749620613201 |
| E2f mediated regulation of dna replication 4 23 4.124866822927765 0.0237749620613201 |
| Global genome nucleotide excision repair gg ner 9 87 2.2699386503067487 0.02573018430516 |
| Apoptotic execution phase 6 47 2.8723973825104103 0.0258673791113288 |
| Cholesterol biosynthesis 4 24 3.918218623481781 0.0274602362801676 |
| Purine catabolism 3 14 5.337190082644628 0.0281854945142632 |
| Negative regulation of mapk pathway 5 36 3.162664398351109 0.0294030506330725 |
| Intra golgi and retrograde golgi to er traffic 15 181 1.783282197111427 0.0315090665936589 |
| Carboxyterminal post translational modifications of tubulin 4 25 3.731251204935416 0.0314674363117242 |
| Methionine salvage pathway 2 6 9.772177419354838 0.0313283564047791 |
| Mitotic prometaphase 16 198 1.7356253704801423 0.0329831328597672 |
| L1cam interactions 9 91 2.158312135268592 0.0331996833734174 |
| Platelet sensitization by ldl 3 15 4.891919191919192 0.0339846578092061 |
| Parasite infection 6 50 2.675720620842572 0.0339036808230292 |
| Rho gtpases activate iqgaps 4 26 3.561280824438719 0.0357999050404339 |
| Sealing of the nuclear envelope ne by escrt iii 4 26 3.561280824438719 0.0357999050404339 |
| Protein folding 8 79 2.213739580339178 0.0383933172409359 |
| Costimulation by the cd28 family 5 39 2.882710893688104 0.0398975682783081 |
| Trna processing 10 109 1.986876966385163 0.0400885046995547 |
| Hdr through homologous recombination hrr 7 66 2.3291449480479134 0.0412596073774315 |
| Oncogenic mapk signaling 7 66 2.3291449480479134 0.0412596073774315 |
| G2 m dna damage checkpoint 7 66 2.3291449480479134 0.0412596073774315 |
| Molybdenum cofactor biosynthesis 2 7 7.816935483870968 0.0424606815374328 |
| Caspase activation via dependence receptors in the absence of ligand 2 7 7.816935483870968 0.0424606815374328 |
| Ephb mediated forward signaling 5 40 2.800057954216169 0.0438404511308739 |
| Dual incision in tc ner 7 67 2.2900882552613715 0.0442221621057979 |
| Mitotic spindle checkpoint 10 111 1.947127089758156 0.0445164345500412 |
| Assembly and cell surface presentation of nmda receptors 4 28 3.263832658569501 0.0454470617698533 |
| Transcription coupled nucleotide excision repair tc ner 8 82 2.123331494760066 0.0462972106215003 |
| Mismatch repair 3 17 4.1922077922077925 0.0472723399635447 |
| Activation of nmda receptors and postsynaptic events 7 68 2.2523121097793064 0.0473183813132007 |
| Recycling pathway of l1 5 41 2.721996844714897 0.0480087672890962 |
| Homologous dna pairing and strand exchange 5 41 2.721996844714897 0.0480087672890962 |
| Signaling by ntrk2 trkb 3 18 3.912323232323232 0.0547354250806853 |
| Dna replication initiation 2 8 6.513440860215054 0.0548161530025184 |
| Rho gtpases activate rhotekin and rhophilins 2 8 6.513440860215054 0.0548161530025184 |
| Synthesis of diphthamide eef2 2 8 6.513440860215054 0.0548161530025184 |
| Dna damage reversal 2 8 6.513440860215054 0.0548161530025184 |
| Synthesis of udp n acetyl glucosamine 2 8 6.513440860215054 0.0548161530025184 |
| Regulation of tp53 activity 12 146 1.7622996130458817 0.0535155053292243 |
| Golgi to er retrograde transport 10 115 1.8721701795472288 0.0543414612497303 |
| Recycling of eif2 gdp 2 8 6.513440860215054 0.0548161530025184 |
| Mhc class ii antigen presentation 9 100 1.9430324276950044 0.0551817111107342 |
| Synthesis of substrates in n glycan biosythesis 5 44 2.5118323191345504 0.061872997913683 |
| Meiotic recombination 4 31 2.9002849002849005 0.0623633603808868 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 3 19 3.6674242424242425 0.0627230635966129 |
| Intracellular signaling by second messengers 17 233 1.5514938014938016 0.0639001689184844 |
| Metabolism of carbohydrates 15 201 1.5881920790756696 0.0673009523323509 |
| Pyrimidine salvage 2 9 5.582373271889401 0.0682492372420068 |
| Signal regulatory protein family interactions 2 9 5.582373271889401 0.0682492372420068 |
| Apoptotic factor mediated response 3 20 3.4513368983957218 0.0712162056075976 |
| Glycogen metabolism 3 20 3.4513368983957218 0.0712162056075976 |
| Runx2 regulates osteoblast differentiation 3 20 3.4513368983957218 0.0712162056075976 |
| Darpp 32 events 3 20 3.4513368983957218 0.0712162056075976 |
| Metalloprotease dubs 3 20 3.4513368983957218 0.0712162056075976 |
| Neurotransmitter receptors and postsynaptic signal transmission 9 105 1.8408742331288344 0.0707250005370495 |
| Assembly of the orc complex at the origin of replication 3 20 3.4513368983957218 0.0712162056075976 |
| Raf activation 4 33 2.699706826748569 0.0752360475117867 |
| Rho gtpases activate wasps and waves 4 33 2.699706826748569 0.0752360475117867 |
| Glutathione conjugation 3 21 3.259259259259259 0.0801939864225387 |
| Met receptor recycling 2 10 4.884072580645161 0.0826256504885364 |
| Gab1 signalosome 2 10 4.884072580645161 0.0826256504885364 |
| Synthesis of pyrophosphates in the cytosol 2 10 4.884072580645161 0.0826256504885364 |
| Receptor mediated mitophagy 2 10 4.884072580645161 0.0826256504885364 |
| Mastl facilitates mitotic progression 2 10 4.884072580645161 0.0826256504885364 |
| Ovarian tumor domain proteases 4 34 2.60944669365722 0.0821355875685036 |
| Signaling by pdgf 4 35 2.525009794958861 0.0893349628841762 |
| Hdr through single strand annealing ssa 4 35 2.525009794958861 0.0893349628841762 |
| Sulfur amino acid metabolism 3 22 3.0874003189792663 0.0896340654819229 |
| Apoptotic cleavage of cellular proteins 4 35 2.525009794958861 0.0893349628841762 |
| Nucleotide catabolism 3 22 3.0874003189792663 0.0896340654819229 |
| Dna double strand break response 5 49 2.2252443297068045 0.0894674368486772 |
| Signaling by met 6 64 2.0269133725820017 0.0913317871121833 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 2 11 4.340949820788531 0.0978216105640502 |
| Suppression of phagosomal maturation 2 11 4.340949820788531 0.0978216105640502 |
| Hdr through mmej alt nhej 2 11 4.340949820788531 0.0978216105640502 |
| Rmts methylate histone arginines 4 36 2.44585020242915 0.0968264519151924 |
| Epha mediated growth cone collapse 3 23 2.9327272727272726 0.0995129309927173 |
| Mtorc1 mediated signalling 3 23 2.9327272727272726 0.0995129309927173 |
| Glycolysis 6 66 1.9589430894308943 0.102256923222589 |
| Nucleotide excision repair 9 114 1.681507449605609 0.1049475666708193 |
| Mitophagy 3 24 2.7927849927849926 0.1098061730973064 |
| Regulation of kit signaling 2 12 3.9064516129032256 0.1137231346556503 |
| Diseases of mitotic cell cycle 4 38 2.301500357227912 0.1126513905607482 |
| Methylation 2 12 3.9064516129032256 0.1137231346556503 |
| Carnitine metabolism 2 12 3.9064516129032256 0.1137231346556503 |
| Other interleukin signaling 2 12 3.9064516129032256 0.1137231346556503 |
| Signaling by braf and raf1 fusions 5 53 2.0389621365787693 0.1154104084629905 |
| Snrnp assembly 5 53 2.0389621365787693 0.1154104084629905 |
| Factors involved in megakaryocyte development and platelet production 9 117 1.634287661895024 0.1181288240266865 |
| Gluconeogenesis 3 25 2.665564738292011 0.1204887281128287 |
| Mtor signalling 4 39 2.235511856564488 0.120966113106861 |
| Clathrin mediated endocytosis 9 119 1.604238706079197 0.1273961443273763 |
| Glycogen breakdown glycogenolysis 2 13 3.550953079178885 0.1302253804689002 |
| Pentose phosphate pathway 2 13 3.550953079178885 0.1302253804689002 |
| Telomere c strand synthesis initiation 2 13 3.550953079178885 0.1302253804689002 |
| Dcc mediated attractive signaling 2 13 3.550953079178885 0.1302253804689002 |
| Sensory processing of sound 4 40 2.1731893837156995 0.129535631100319 |
| Early phase of hiv life cycle 2 13 3.550953079178885 0.1302253804689002 |
| Inositol phosphate metabolism 4 40 2.1731893837156995 0.129535631100319 |
| Maturation of sars cov 2 nucleoprotein 2 13 3.550953079178885 0.1302253804689002 |
| Copii mediated vesicle transport 5 55 1.9569979716024344 0.1295844377433678 |
| Runx2 regulates bone development 3 26 2.549407114624506 0.1315350963393062 |
| Ret signaling 3 26 2.549407114624506 0.1315350963393062 |
| Nuclear envelope ne reassembly 6 71 1.807317073170732 0.1323780825119418 |
| Fcgamma receptor fcgr dependent phagocytosis 6 72 1.779748706577975 0.1388611993576404 |
| Runx2 regulates chondrocyte maturation 1 3 9.754527162977867 0.1395007501750084 |
| Runx1 regulates transcription of genes involved in wnt signaling 1 3 9.754527162977867 0.1395007501750084 |
| Tnfr1 mediated ceramide production 1 3 9.754527162977867 0.1395007501750084 |
| G alpha i signalling events 7 88 1.6926655100450076 0.1379525018897012 |
| Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 1 3 9.754527162977867 0.1395007501750084 |
| Activated ntrk2 signals through cdk5 1 3 9.754527162977867 0.1395007501750084 |
| Nonhomologous end joining nhej 4 41 2.114235693183061 0.1383493461091194 |
| Formyl peptide receptors bind formyl peptides and many other ligands 1 3 9.754527162977867 0.1395007501750084 |
| Transmission across chemical synapses 10 139 1.520047019951709 0.1419916911786224 |
| Formation of incision complex in gg ner 4 42 2.058384828467931 0.1473962800256471 |
| Spry regulation of fgf signaling 2 14 3.254704301075269 0.1472320281277068 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 2 14 3.254704301075269 0.1472320281277068 |
| Tgf beta receptor signaling activates smads 3 28 2.344969696969697 0.1546162324240269 |
| Neuronal system 12 177 1.4265619154508042 0.1568092989481765 |
| Tp53 regulates transcription of cell cycle genes 4 43 2.0053981106612686 0.1566651346062924 |
| Metabolism of water soluble vitamins and cofactors 7 91 1.631704005431093 0.1560546492252061 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 5 59 1.8112839005333932 0.160126065260348 |
| Raf independent mapk1 3 activation 2 15 3.004032258064516 0.1646547004840289 |
| Synthesis of pips at the golgi membrane 2 15 3.004032258064516 0.1646547004840289 |
| Signaling by ctnnb1 phospho site mutants 2 15 3.004032258064516 0.1646547004840289 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 3 29 2.2545454545454544 0.1665994534041104 |
| Hemostasis 22 361 1.275984730175256 0.1670863243369741 |
| Leishmania infection 8 110 1.5359743897559024 0.1690708050593155 |
| Beta catenin phosphorylation cascade 2 16 2.7891705069124426 0.1824124195300006 |
| Signaling by mapk mutants 1 4 6.502347417840376 0.1815422125939431 |
| Synthesis of pips at the early endosome membrane 2 16 2.7891705069124426 0.1824124195300006 |
| Abacavir metabolism 1 4 6.502347417840376 0.1815422125939431 |
| Irs activation 1 4 6.502347417840376 0.1815422125939431 |
| Vitamin b2 riboflavin metabolism 1 4 6.502347417840376 0.1815422125939431 |
| Runx3 regulates immune response and cell migration 1 4 6.502347417840376 0.1815422125939431 |
| Activated ntrk2 signals through fyn 1 4 6.502347417840376 0.1815422125939431 |
| Phenylalanine metabolism 1 4 6.502347417840376 0.1815422125939431 |
| N glycan trimming and elongation in the cis golgi 1 4 6.502347417840376 0.1815422125939431 |
| Activated ntrk3 signals through pi3k 1 4 6.502347417840376 0.1815422125939431 |
| G2 phase 1 4 6.502347417840376 0.1815422125939431 |
| Tp53 regulates transcription of dna repair genes 5 61 1.7462329759490005 0.1763957549795013 |
| Runx1 regulates transcription of genes involved in interleukin signaling 1 4 6.502347417840376 0.1815422125939431 |
| Runx1 regulates transcription of genes involved in differentiation of keratinocytes 1 4 6.502347417840376 0.1815422125939431 |
| Runx1 regulates expression of components of tight junctions 1 4 6.502347417840376 0.1815422125939431 |
| Runx1 regulates transcription of genes involved in bcr signaling 1 4 6.502347417840376 0.1815422125939431 |
| Stat5 activation 1 4 6.502347417840376 0.1815422125939431 |
| Protein methylation 2 16 2.7891705069124426 0.1824124195300006 |
| Cilium assembly 12 183 1.375640747960436 0.1841895794805187 |
| Hcmv early events 6 79 1.6079184764450385 0.1880908838571592 |
| Map2k and mapk activation 3 31 2.093073593073593 0.1913237113672655 |
| Interleukin 3 interleukin 5 and gm csf signaling 3 31 2.093073593073593 0.1913237113672655 |
| Opioid signalling 5 63 1.6856683220255997 0.1932605064645131 |
| Kinesins 4 47 1.8180962244609733 0.1957256915247766 |
| Glucose metabolism 6 80 1.5860250494396837 0.1956233162754421 |
| Negative regulation of fgfr4 signaling 2 17 2.602956989247312 0.2004310968060411 |
| Negative regulation of fgfr1 signaling 2 17 2.602956989247312 0.2004310968060411 |
| Negative regulation of fgfr3 signaling 2 17 2.602956989247312 0.2004310968060411 |
| Negative regulation of fgfr2 signaling 2 17 2.602956989247312 0.2004310968060411 |
| Transcriptional regulation by tp53 20 333 1.2545617388747043 0.198185585234977 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 2 17 2.602956989247312 0.2004310968060411 |
| Sumo is conjugated to e1 uba2 sae1 1 5 4.8762575452716295 0.2215335762210877 |
| Netrin 1 signaling 3 33 1.953131313131313 0.2168926648719501 |
| Ethanol oxidation 1 5 4.8762575452716295 0.2215335762210877 |
| Runx1 regulates estrogen receptor mediated transcription 1 5 4.8762575452716295 0.2215335762210877 |
| Copi dependent golgi to er retrograde traffic 6 83 1.5237567310738045 0.218869806801983 |
| Myoclonic epilepsy of lafora 1 5 4.8762575452716295 0.2215335762210877 |
| Vxpx cargo targeting to cilium 2 18 2.4400201612903225 0.2186430557746356 |
| Pd 1 signaling 1 5 4.8762575452716295 0.2215335762210877 |
| Runx2 regulates genes involved in cell migration 1 5 4.8762575452716295 0.2215335762210877 |
| Runx1 regulates transcription of genes involved in differentiation of myeloid cells 1 5 4.8762575452716295 0.2215335762210877 |
| Ptk6 regulates cell cycle 1 5 4.8762575452716295 0.2215335762210877 |
| Met activates ptpn11 1 5 4.8762575452716295 0.2215335762210877 |
| Rho gtpases activate cit 2 18 2.4400201612903225 0.2186430557746356 |
| Ras signaling downstream of nf1 loss of function variants 1 5 4.8762575452716295 0.2215335762210877 |
| Sema4d induced cell migration and growth cone collapse 2 18 2.4400201612903225 0.2186430557746356 |
| Fructose metabolism 1 5 4.8762575452716295 0.2215335762210877 |
| Synthesis of pips at the er membrane 1 5 4.8762575452716295 0.2215335762210877 |
| Regulation of signaling by cbl 2 18 2.4400201612903225 0.2186430557746356 |
| Synthesis of dolichyl phosphate 1 5 4.8762575452716295 0.2215335762210877 |
| Formation of xylulose 5 phosphate 1 5 4.8762575452716295 0.2215335762210877 |
| P75ntr regulates axonogenesis 1 5 4.8762575452716295 0.2215335762210877 |
| Caspase activation via extrinsic apoptotic signalling pathway 2 18 2.4400201612903225 0.2186430557746356 |
| Signaling by kit in disease 2 18 2.4400201612903225 0.2186430557746356 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 2 18 2.4400201612903225 0.2186430557746356 |
| Pre notch processing in the endoplasmic reticulum 1 5 4.8762575452716295 0.2215335762210877 |
| Ncam signaling for neurite out growth 3 34 1.8899315738025413 0.229933672353323 |
| Transcriptional regulation by e2f6 3 34 1.8899315738025413 0.229933672353323 |
| Tp53 regulates transcription of cell death genes 3 34 1.8899315738025413 0.229933672353323 |
| Hcmv infection 7 102 1.4411190910065388 0.2305964038641619 |
| Platelet homeostasis 4 51 1.6626755103798776 0.2373860395762566 |
| Rho gtpases activate rocks 2 19 2.2962523719165087 0.2369865842622187 |
| Pp2a mediated dephosphorylation of key metabolic factors 1 6 3.900603621730382 0.2595746201812825 |
| Signaling by moderate kinase activity braf mutants 3 36 1.7750229568411386 0.2564137422230053 |
| Aflatoxin activation and detoxification 1 6 3.900603621730382 0.2595746201812825 |
| Gdp fucose biosynthesis 1 6 3.900603621730382 0.2595746201812825 |
| Abacavir transport and metabolism 1 6 3.900603621730382 0.2595746201812825 |
| Erbb2 regulates cell motility 1 6 3.900603621730382 0.2595746201812825 |
| Fatty acids bound to gpr40 ffar1 regulate insulin secretion 1 6 3.900603621730382 0.2595746201812825 |
| Creatine metabolism 1 6 3.900603621730382 0.2595746201812825 |
| Signaling by alk in cancer 4 52 1.627867746288799 0.2481167977468243 |
| Alpha oxidation of phytanate 1 6 3.900603621730382 0.2595746201812825 |
| Nucleotide salvage 2 20 2.1684587813620078 0.255405515221392 |
| Intrinsic pathway for apoptosis 4 53 1.594480707262662 0.2589499723837208 |
| Response of mtb to phagocytosis 2 20 2.1684587813620078 0.255405515221392 |
| Phosphate bond hydrolysis by nudt proteins 1 6 3.900603621730382 0.2595746201812825 |
| Phenylalanine and tyrosine metabolism 1 6 3.900603621730382 0.2595746201812825 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 2 20 2.1684587813620078 0.255405515221392 |
| Signal transduction by l1 2 20 2.1684587813620078 0.255405515221392 |
| Diseases of programmed cell death 4 53 1.594480707262662 0.2589499723837208 |
| Adenylate cyclase inhibitory pathway 1 6 3.900603621730382 0.2595746201812825 |
| Cell surface interactions at the vascular wall 5 70 1.5030425963488845 0.2561486974132024 |
| Synthesis of ip3 and ip4 in the cytosol 2 20 2.1684587813620078 0.255405515221392 |
| Stat5 activation downstream of flt3 itd mutants 1 6 3.900603621730382 0.2595746201812825 |
| Vitamin c ascorbate metabolism 1 6 3.900603621730382 0.2595746201812825 |
| Rho gtpases activate nadph oxidases 0 13 0.0 1.0 |
| Diseases of metabolism 3 131 0.453125 0.958183920936633 |
| Pyruvate metabolism 1 26 0.7785110663983903 0.7284504433708964 |
| Tryptophan catabolism 0 6 0.0 1.0 |
| Phospholipase c mediated cascade fgfr4 0 3 0.0 1.0 |
| Lysine catabolism 0 11 0.0 1.0 |
| Pyroptosis 1 16 1.298859825620389 0.5514871371697274 |
| Propionyl coa catabolism 0 5 0.0 1.0 |
| Downstream signaling of activated fgfr1 1 15 1.3917792469100316 0.5284199673110125 |
| Histidine catabolism 0 3 0.0 1.0 |
| Protein repair 0 5 0.0 1.0 |
| Pi 3k cascade fgfr1 1 8 2.785570566254671 0.3301808657155594 |
| Branched chain amino acid catabolism 0 22 0.0 1.0 |
| Shc mediated cascade fgfr1 0 8 0.0 1.0 |
| Frs mediated fgfr1 signaling 1 9 2.437122736418511 0.3629223192764827 |
| Urea cycle 0 6 0.0 1.0 |
| Tnfs bind their physiological receptors 0 1 0.0 1.0 |
| Fructose catabolism 0 3 0.0 1.0 |
| Galactose catabolism 0 5 0.0 1.0 |
| Negative feedback regulation of mapk pathway 0 6 0.0 1.0 |
| Constitutive signaling by akt1 e17k in cancer 1 25 0.8110328638497653 0.714470118842069 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 0 5 0.0 1.0 |
| Pyruvate metabolism and citric acid tca cycle 1 48 0.41315980992337 0.9101252243720072 |
| Downstream signaling of activated fgfr2 1 14 1.498993963782696 0.5041689495301098 |
| Pyrimidine catabolism 0 6 0.0 1.0 |
| Rna polymerase i transcription initiation 1 49 0.4045103957075788 0.9145357129666144 |
| Signaling by fgfr4 in disease 0 11 0.0 1.0 |
| Rna polymerase i promoter escape 1 42 0.4739166707562448 0.8784624909010724 |
| Rna polymerase iii chain elongation 0 19 0.0 1.0 |
| Rna polymerase ii transcription termination 2 66 0.6069808467741935 0.8398302536975839 |
| Signaling by fgfr2 in disease 0 28 0.0 1.0 |
| Signaling by fgfr1 in disease 1 29 0.694883587237712 0.7664238447790522 |
| Signaling by fgfr4 2 26 1.6253360215053765 0.3649620055651655 |
| Signaling by fgfr3 2 27 1.5601612903225806 0.3827254031641982 |
| Rna polymerase i transcription termination 1 32 0.627442071785552 0.7990962171858123 |
| Rna polymerase i transcription 1 63 0.3127149996754721 0.957771221685996 |
| Signaling by fgfr2 2 51 0.7940256747860435 0.7192802822232048 |
| Signaling by fgfr1 2 28 1.5 0.4002722624509632 |
| Downstream signaling of activated fgfr4 1 14 1.498993963782696 0.5041689495301098 |
| Pi 3k cascade fgfr4 1 8 2.785570566254671 0.3301808657155594 |
| Rna polymerase ii transcription 47 969 0.9919436682041836 0.5441617700711243 |
| Transport of nucleotide sugars 0 4 0.0 1.0 |
| Fgfrl1 modulation of fgfr1 signaling 0 2 0.0 1.0 |
| Response to metal ions 0 5 0.0 1.0 |
| Frs mediated fgfr2 signaling 1 9 2.437122736418511 0.3629223192764827 |
| Shc mediated cascade fgfr3 0 8 0.0 1.0 |
| Frs mediated fgfr3 signaling 1 9 2.437122736418511 0.3629223192764827 |
| Downstream signaling of activated fgfr3 1 14 1.498993963782696 0.5041689495301098 |
| Citric acid cycle tca cycle 0 21 0.0 1.0 |
| Pi 3k cascade fgfr3 1 8 2.785570566254671 0.3301808657155594 |
| Lgi adam interactions 0 5 0.0 1.0 |
| Mrna capping 2 29 1.444295101553166 0.4175813594218437 |
| Mrna splicing minor pathway 2 52 0.7780645161290323 0.7292466823198303 |
| Mrna splicing 10 188 1.095966107938847 0.4373588516646142 |
| Mrna editing c to u conversion 0 2 0.0 1.0 |
| Transport of mature transcript to cytoplasm 2 81 0.490965700285831 0.9115254748304248 |
| Processing of capped intron containing pre mrna 11 239 0.938164198998523 0.6244472357289286 |
| Diseases of carbohydrate metabolism 1 23 0.8849460398756174 0.6843179386047307 |
| Metallothioneins bind metals 0 2 0.0 1.0 |
| Clec7a inflammasome pathway 0 4 0.0 1.0 |
| Frs mediated fgfr4 signaling 1 9 2.437122736418511 0.3629223192764827 |
| Pi 3k cascade fgfr2 1 8 2.785570566254671 0.3301808657155594 |
| Phospholipase c mediated cascade fgfr2 0 3 0.0 1.0 |
| Josephin domain dubs 0 9 0.0 1.0 |
| Map3k8 tpl2 dependent mapk1 3 activation 1 14 1.498993963782696 0.5041689495301098 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 1 16 1.298859825620389 0.5514871371697274 |
| Cdc6 association with the orc origin complex 1 12 1.7719041521858423 0.451869757084416 |
| Fgfr2 alternative splicing 0 26 0.0 1.0 |
| Tp53 regulates transcription of death receptors and ligands 0 10 0.0 1.0 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0 11 0.0 1.0 |
| Activation of smo 0 11 0.0 1.0 |
| Tp53 regulates transcription of genes involved in cytochrome c release 0 16 0.0 1.0 |
| Antimicrobial peptides 1 7 3.250167672702884 0.295760276625992 |
| Shc mediated cascade fgfr4 0 8 0.0 1.0 |
| Complex i biogenesis 1 56 0.3527711724894823 0.9399171137219118 |
| Rho gtpases activate ktn1 1 11 1.9492957746478876 0.4236908718837023 |
| Choline catabolism 0 4 0.0 1.0 |
| Mitotic prophase 4 93 0.8742209889460038 0.6723930166663851 |
| Protein protein interactions at synapses 2 46 0.8847140762463344 0.6647468144888726 |
| Neurexins and neuroligins 1 28 0.720694537595946 0.7543947935478624 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 1 13 1.6240778001341385 0.4786734551421467 |
| Rrna modification in the mitochondrion 0 6 0.0 1.0 |
| Glycerophospholipid catabolism 0 4 0.0 1.0 |
| Regulation of tp53 activity through association with co factors 0 12 0.0 1.0 |
| Rna polymerase ii transcribes snrna genes 0 73 0.0 1.0 |
| Ligand receptor interactions 0 2 0.0 1.0 |
| Tp53 regulates metabolic genes 1 84 0.2330852585391869 0.9853603776980232 |
| Formation of the cornified envelope 0 24 0.0 1.0 |
| Negative regulation of met activity 1 20 1.0249920576088107 0.6330296848923271 |
| Rho gtpases activate paks 0 19 0.0 1.0 |
| Met receptor activation 0 4 0.0 1.0 |
| Metabolism of fat soluble vitamins 0 29 0.0 1.0 |
| Intra golgi traffic 3 42 1.501010101010101 0.3375295111799605 |
| Retrograde transport at the trans golgi network 3 49 1.27167325428195 0.4313191825222751 |
| Regulation of tp53 expression and degradation 2 33 1.257414151925078 0.4841018564616677 |
| Keratinization 0 24 0.0 1.0 |
| Regulation of tp53 activity through methylation 1 16 1.298859825620389 0.5514871371697274 |
| Pi5p regulates tp53 acetylation 0 9 0.0 1.0 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 1 27 0.7484909456740443 0.7417475603012252 |
| Regulation of tp53 activity through acetylation 0 30 0.0 1.0 |
| Surfactant metabolism 0 8 0.0 1.0 |
| Il 6 type cytokine receptor ligand interactions 0 6 0.0 1.0 |
| Mitotic telophase cytokinesis 0 13 0.0 1.0 |
| Constitutive signaling by egfrviii 0 14 0.0 1.0 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0 7 0.0 1.0 |
| Dna damage recognition in gg ner 3 37 1.722638146167558 0.2698089294696847 |
| G1 s specific transcription 2 29 1.444295101553166 0.4175813594218437 |
| Cargo concentration in the er 2 23 1.8581029185867897 0.3106281566010752 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 1 26 0.7785110663983903 0.7284504433708964 |
| Sensing of dna double strand breaks 0 6 0.0 1.0 |
| Resolution of d loop structures 1 32 0.627442071785552 0.7990962171858123 |
| Cd22 mediated bcr regulation 0 2 0.0 1.0 |
| Cd209 dc sign signaling 0 18 0.0 1.0 |
| Cyclin a b1 b2 associated events during g2 m transition 2 24 1.7734604105571847 0.3288847005661894 |
| Dectin 2 family 0 4 0.0 1.0 |
| Diseases associated with surfactant metabolism 0 1 0.0 1.0 |
| Regulation of tlr by endogenous ligand 0 3 0.0 1.0 |
| G2 m dna replication checkpoint 0 5 0.0 1.0 |
| Trafficking of myristoylated proteins to the cilium 0 4 0.0 1.0 |
| Trna modification in the mitochondrion 0 9 0.0 1.0 |
| Deposition of new cenpa containing nucleosomes at the centromere 1 34 0.589293335772209 0.8183019856004505 |
| Inflammasomes 1 12 1.7719041521858423 0.451869757084416 |
| Interleukin 4 and interleukin 13 signaling 1 40 0.4983232729711603 0.8656048739892852 |
| Trna processing in the mitochondrion 0 5 0.0 1.0 |
| Trna processing in the nucleus 3 60 1.0250930356193515 0.5670328435948879 |
| Interleukin 10 signaling 0 6 0.0 1.0 |
| Interleukin 6 family signaling 1 10 2.1661077576570533 0.3940663935801297 |
| Fanconi anemia pathway 2 36 1.146110056925996 0.530799029376844 |
| Synthesis of wybutosine at g37 of trna phe 0 6 0.0 1.0 |
| Formation of tc ner pre incision complex 3 53 1.1694545454545455 0.4827904979970205 |
| Highly calcium permeable nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0 14 0.0 1.0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors 0 1 0.0 1.0 |
| Presynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Gli proteins bind promoters of hh responsive genes to promote transcription 0 2 0.0 1.0 |
| Rho gtpases activate pkns 2 40 1.0250424448217317 0.5884384065253555 |
| Respiratory electron transport 2 101 0.3909661127403063 0.961311310854044 |
| Interleukin 6 signaling 1 8 2.785570566254671 0.3301808657155594 |
| Met activates ptk2 signaling 1 19 1.082047842611223 0.6141484764039431 |
| Base excision repair ap site formation 0 23 0.0 1.0 |
| Irak1 recruits ikk complex 0 12 0.0 1.0 |
| Ion transport by p type atpases 1 31 0.6484238765928907 0.788746565408226 |
| Negative regulators of ddx58 ifih1 signaling 2 29 1.444295101553166 0.4175813594218437 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 1 13 1.6240778001341385 0.4786734551421467 |
| Traf6 mediated nf kb activation 1 22 0.9271821404618186 0.6680705567912797 |
| Traf6 mediated irf7 activation 1 15 1.3917792469100316 0.5284199673110125 |
| Traf3 dependent irf activation pathway 1 13 1.6240778001341385 0.4786734551421467 |
| Ikk complex recruitment mediated by rip1 1 16 1.298859825620389 0.5514871371697274 |
| Transferrin endocytosis and recycling 1 18 1.1458160729080364 0.5942978505128852 |
| Endosomal sorting complex required for transport escrt 1 30 0.6708527024214251 0.7778648721483832 |
| O linked glycosylation of mucins 1 22 0.9271821404618186 0.6680705567912797 |
| Interferon signaling 6 128 0.957217113154738 0.5998988534447532 |
| Regulation of ifna signaling 1 8 2.785570566254671 0.3301808657155594 |
| Interleukin receptor shc signaling 0 14 0.0 1.0 |
| Interferon alpha beta signaling 2 31 1.3444104560622914 0.451414074418919 |
| Rhof gtpase cycle 1 42 0.4739166707562448 0.8784624909010724 |
| Iron uptake and transport 3 38 1.6732467532467532 0.2832795756669947 |
| Irak2 mediated activation of tak1 complex 0 9 0.0 1.0 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 1 11 1.9492957746478876 0.4236908718837023 |
| Class i peroxisomal membrane protein import 1 19 1.082047842611223 0.6141484764039431 |
| Activation of rac1 downstream of nmdars 0 6 0.0 1.0 |
| Foxo mediated transcription of cell cycle genes 0 13 0.0 1.0 |
| Regulation of foxo transcriptional activity by acetylation 0 10 0.0 1.0 |
| Negative regulation of nmda receptor mediated neuronal transmission 1 14 1.498993963782696 0.5041689495301098 |
| Transcriptional regulation of granulopoiesis 2 34 1.2179939516129032 0.4999873679723159 |
| Postmitotic nuclear pore complex npc reformation 1 27 0.7484909456740443 0.7417475603012252 |
| Late endosomal microautophagy 2 29 1.444295101553166 0.4175813594218437 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0 18 0.0 1.0 |
| Foxo mediated transcription of cell death genes 0 12 0.0 1.0 |
| Regulation of localization of foxo transcription factors 0 13 0.0 1.0 |
| Foxo mediated transcription 0 47 0.0 1.0 |
| Chaperone mediated autophagy 1 16 1.298859825620389 0.5514871371697274 |
| Lipophagy 1 8 2.785570566254671 0.3301808657155594 |
| Hcmv late events 2 62 0.6477150537634409 0.8132996333441835 |
| Protein localization 6 142 0.8574246771879483 0.6990649600195342 |
| Flt3 signaling 2 27 1.5601612903225806 0.3827254031641982 |
| Diseases of base excision repair 0 4 0.0 1.0 |
| Activated ntrk3 signals through ras 0 6 0.0 1.0 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 0 20 0.0 1.0 |
| Signaling by ntrk3 trkc 1 15 1.3917792469100316 0.5284199673110125 |
| Tysnd1 cleaves peroxisomal proteins 0 7 0.0 1.0 |
| Interleukin 27 signaling 0 8 0.0 1.0 |
| Interleukin 23 signaling 0 5 0.0 1.0 |
| Interleukin 2 signaling 0 5 0.0 1.0 |
| Biosynthesis of maresins 0 1 0.0 1.0 |
| Biosynthesis of epa derived spms 0 3 0.0 1.0 |
| Biosynthesis of specialized proresolving mediators spms 0 6 0.0 1.0 |
| Estrogen dependent gene expression 2 90 0.4403409090909091 0.9387577705701072 |
| Interleukin 21 signaling 0 5 0.0 1.0 |
| Noncanonical activation of notch3 0 8 0.0 1.0 |
| Ticam1 traf6 dependent induction of tak1 complex 0 10 0.0 1.0 |
| Ticam1 dependent activation of irf3 irf7 0 10 0.0 1.0 |
| Tlr3 mediated ticam1 dependent programmed cell death 0 5 0.0 1.0 |
| Notch4 activation and transmission of signal to the nucleus 0 8 0.0 1.0 |
| Notch4 intracellular domain regulates transcription 0 15 0.0 1.0 |
| Notch3 intracellular domain regulates transcription 0 18 0.0 1.0 |
| Notch3 activation and transmission of signal to the nucleus 0 18 0.0 1.0 |
| Interleukin 36 pathway 0 1 0.0 1.0 |
| Loss of mecp2 binding ability to the ncor smrt complex 0 7 0.0 1.0 |
| Regulation of mecp2 expression and activity 0 30 0.0 1.0 |
| Mecp2 regulates neuronal receptors and channels 0 12 0.0 1.0 |
| Peroxisomal protein import 1 51 0.3882494969818914 0.9227191737187296 |
| Ntrk2 activates rac1 0 3 0.0 1.0 |
| Ngf stimulated transcription 1 22 0.9271821404618186 0.6680705567912797 |
| Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose 0 3 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake 0 3 0.0 1.0 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0 26 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0 7 0.0 1.0 |
| Activated ntrk2 signals through frs2 and frs3 1 7 3.250167672702884 0.295760276625992 |
| Activated ntrk2 signals through pi3k 0 4 0.0 1.0 |
| Erythropoietin activates ras 1 11 1.9492957746478876 0.4236908718837023 |
| Erythropoietin activates stat5 0 4 0.0 1.0 |
| Erythropoietin activates phospholipase c gamma plcg 0 5 0.0 1.0 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 8 0.0 1.0 |
| Activated ntrk2 signals through ras 0 6 0.0 1.0 |
| Nr1h2 and nr1h3 mediated signaling 0 31 0.0 1.0 |
| Mecp2 regulates transcription factors 0 4 0.0 1.0 |
| Mecp2 regulates transcription of neuronal ligands 0 4 0.0 1.0 |
| Blood group systems biosynthesis 0 5 0.0 1.0 |
| Rhot1 gtpase cycle 0 5 0.0 1.0 |
| Long term potentiation 1 11 1.9492957746478876 0.4236908718837023 |
| Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis 0 4 0.0 1.0 |
| Negative regulation of flt3 0 8 0.0 1.0 |
| Rhobtb3 atpase cycle 0 9 0.0 1.0 |
| Inactivation of csf3 g csf signaling 0 17 0.0 1.0 |
| Signaling by flt3 itd and tkd mutants 1 12 1.7719041521858423 0.451869757084416 |
| Signaling by flt3 fusion proteins 1 16 1.298859825620389 0.5514871371697274 |
| Stat3 nuclear events downstream of alk signaling 0 6 0.0 1.0 |
| Alk mutants bind tkis 0 12 0.0 1.0 |
| Flt3 signaling through src family kinases 0 2 0.0 1.0 |
| Rnd1 gtpase cycle 0 36 0.0 1.0 |
| Rnd3 gtpase cycle 1 39 0.5114899925871016 0.8586757123257109 |
| Translation of sars cov 2 structural proteins 2 41 0.9986559139784946 0.6020019880837094 |
| Attachment and entry 0 4 0.0 1.0 |
| Maturation of sars cov 2 spike protein 0 24 0.0 1.0 |
| Sars cov 2 infection 2 62 0.6477150537634409 0.8132996333441835 |
| Defective ripk1 mediated regulated necrosis 0 6 0.0 1.0 |
| Transcriptional regulation of testis differentiation 0 4 0.0 1.0 |
| Rnd2 gtpase cycle 0 40 0.0 1.0 |
| Flt3 signaling by cbl mutants 0 4 0.0 1.0 |
| Rhobtb gtpase cycle 1 33 0.607771629778672 0.8089397909574001 |
| Heme signaling 0 36 0.0 1.0 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 1 20 1.0249920576088107 0.6330296848923271 |
| Antigen presentation folding assembly and peptide loading of class i mhc 2 24 1.7734604105571847 0.3288847005661894 |
| Growth hormone receptor signaling 0 15 0.0 1.0 |
| Gaba b receptor activation 1 16 1.298859825620389 0.5514871371697274 |
| Gaba receptor activation 1 18 1.1458160729080364 0.5942978505128852 |
| Serine biosynthesis 1 7 3.250167672702884 0.295760276625992 |
| Amyloid fiber formation 0 41 0.0 1.0 |
| Termination of o glycan biosynthesis 0 4 0.0 1.0 |
| Reactions specific to the complex n glycan synthesis pathway 0 6 0.0 1.0 |
| N glycan antennae elongation 0 8 0.0 1.0 |
| N glycan antennae elongation in the medial trans golgi 0 15 0.0 1.0 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0 10 0.0 1.0 |
| Defective intrinsic pathway for apoptosis 2 24 1.7734604105571847 0.3288847005661894 |
| Sensory perception of taste 0 4 0.0 1.0 |
| Signaling by rho gtpases miro gtpases and rhobtb3 29 593 1.0013987811701373 0.5258961562156335 |
| Miro gtpase cycle 1 8 2.785570566254671 0.3301808657155594 |
| Sensory perception 5 84 1.2348833029501631 0.3917476189623123 |
| Translation of sars cov 1 structural proteins 0 22 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 0 6 0.0 1.0 |
| Maturation of sars cov 1 spike protein 0 5 0.0 1.0 |
| Maturation of sars cov 1 nucleoprotein 0 9 0.0 1.0 |
| Purinergic signaling in leishmaniasis infection 1 12 1.7719041521858423 0.451869757084416 |
| Adora2b mediated anti inflammatory cytokines production 1 30 0.6708527024214251 0.7778648721483832 |
| Signaling by mras complex mutants 1 8 2.785570566254671 0.3301808657155594 |
| Defects of contact activation system cas and kallikrein kinin system kks 0 5 0.0 1.0 |
| Response of eif2ak1 hri to heme deficiency 1 10 2.1661077576570533 0.3940663935801297 |
| Ras processing 0 19 0.0 1.0 |
| Alpha protein kinase 1 signaling pathway 0 9 0.0 1.0 |
| Defective factor viii causes hemophilia a 0 3 0.0 1.0 |
| Amino acids regulate mtorc1 2 45 0.9053825956489122 0.6528681906484021 |
| Prevention of phagosomal lysosomal fusion 1 8 2.785570566254671 0.3301808657155594 |
| Infection with mycobacterium tuberculosis 2 21 2.05411714770798 0.2738488340493723 |
| Suppression of apoptosis 0 6 0.0 1.0 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 0 15 0.0 1.0 |
| Estrogen stimulated signaling through prkcz 0 6 0.0 1.0 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 1 11 1.9492957746478876 0.4236908718837023 |
| Constitutive signaling by overexpressed erbb2 0 11 0.0 1.0 |
| Modulation by mtb of host immune system 0 4 0.0 1.0 |
| Sensory processing of sound by outer hair cells of the cochlea 2 25 1.6961781206171107 0.3470060894740981 |
| Cd163 mediating an anti inflammatory response 0 5 0.0 1.0 |
| Anti inflammatory response favouring leishmania parasite infection 3 46 1.3608174770965469 0.3915384662813004 |
| Flt3 signaling in disease 2 22 1.9512096774193548 0.2922703109028879 |
| Sars cov infections 6 128 0.957217113154738 0.5998988534447532 |
| Translation of replicase and assembly of the replication transcription complex 0 13 0.0 1.0 |
| Potential therapeutics for sars 4 68 1.2188765182186234 0.4263222365825169 |
| Sars cov 1 infection 0 42 0.0 1.0 |
| Diseases of dna repair 1 33 0.607771629778672 0.8089397909574001 |
| Signaling by csf3 g csf 1 22 0.9271821404618186 0.6680705567912797 |
| Signaling by membrane tethered fusions of pdgfra or pdgfrb 0 3 0.0 1.0 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0 11 0.0 1.0 |
| Defective f9 activation 0 1 0.0 1.0 |
| Signaling by pdgfr in disease 0 17 0.0 1.0 |
| Inhibition of dna recombination at telomere 0 28 0.0 1.0 |
| Defective factor ix causes hemophilia b 0 3 0.0 1.0 |
| Signaling by erbb2 ecd mutants 0 15 0.0 1.0 |
| Pexophagy 1 9 2.437122736418511 0.3629223192764827 |
| Killing mechanisms 0 9 0.0 1.0 |
| Fcgr3a mediated il10 synthesis 2 23 1.8581029185867897 0.3106281566010752 |
| Maturation of protein 3a 0 5 0.0 1.0 |
| Rhov gtpase cycle 2 35 1.180962854349951 0.5155554023099136 |
| Rac3 gtpase cycle 2 83 0.4787435284747112 0.918414998792566 |
| Rhobtb1 gtpase cycle 1 22 0.9271821404618186 0.6680705567912797 |
| Protein ubiquitination 3 58 1.0625895316804408 0.5438179728252587 |
| Met activates pi3k akt signaling 0 6 0.0 1.0 |
| Met activates ras signaling 1 11 1.9492957746478876 0.4236908718837023 |
| Signaling by fgfr2 iiia tm 0 18 0.0 1.0 |
| Butyrophilin btn family interactions 0 5 0.0 1.0 |
| Phosphate bond hydrolysis by ntpdase proteins 0 4 0.0 1.0 |
| Synaptic adhesion like molecules 1 11 1.9492957746478876 0.4236908718837023 |
| Signaling by mst1 0 3 0.0 1.0 |
| Ptk6 expression 0 2 0.0 1.0 |
| Ptk6 regulates rtks and their effectors akt1 and dok1 0 7 0.0 1.0 |
| Ptk6 regulates proteins involved in rna processing 0 3 0.0 1.0 |
| Wax and plasmalogen biosynthesis 0 5 0.0 1.0 |
| Signaling by ptk6 2 36 1.146110056925996 0.530799029376844 |
| Erbb2 activates ptk6 signaling 0 3 0.0 1.0 |
| Gastrin creb signalling pathway via pkc and mapk 0 14 0.0 1.0 |
| Transport of organic anions 0 3 0.0 1.0 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 1 13 1.6240778001341385 0.4786734551421467 |
| Signaling by fgfr3 fusions in cancer 0 10 0.0 1.0 |
| Transcriptional regulation by ventx 1 37 0.5400178850883076 0.8437295850039954 |
| Tbc rabgaps 3 39 1.6265993265993266 0.2968056975451645 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0 5 0.0 1.0 |
| Rrna processing in the mitochondrion 0 10 0.0 1.0 |
| Tfap2 ap 2 family regulates transcription of cell cycle factors 0 5 0.0 1.0 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0 7 0.0 1.0 |
| Activation of the tfap2 ap 2 family of transcription factors 0 8 0.0 1.0 |
| Negative regulation of activity of tfap2 ap 2 family transcription factors 0 7 0.0 1.0 |
| E3 ubiquitin ligases ubiquitinate target proteins 3 40 1.5824733824733823 0.3103681353614002 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 0 26 0.0 1.0 |
| Vldlr internalisation and degradation 0 9 0.0 1.0 |
| Vldl assembly 0 3 0.0 1.0 |
| Reelin signalling pathway 0 3 0.0 1.0 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0 27 0.0 1.0 |
| Downregulation of erbb2 signaling 0 18 0.0 1.0 |
| Ptk6 promotes hif1a stabilization 0 2 0.0 1.0 |
| Cargo recognition for clathrin mediated endocytosis 5 78 1.337214148767679 0.3328829292245179 |
| Interleukin 20 family signaling 1 11 1.9492957746478876 0.4236908718837023 |
| Aurka activation by tpx2 4 73 1.1299653816816289 0.4808642038976582 |
| Advanced glycosylation endproduct receptor signaling 1 9 2.437122736418511 0.3629223192764827 |
| Rab geranylgeranylation 4 54 1.5624291497975709 0.2698738667135572 |
| Regulation of ifng signaling 1 10 2.1661077576570533 0.3940663935801297 |
| The nlrp3 inflammasome 1 10 2.1661077576570533 0.3940663935801297 |
| Synthesis of very long chain fatty acyl coas 0 17 0.0 1.0 |
| Dissolution of fibrin clot 0 7 0.0 1.0 |
| Trail signaling 0 6 0.0 1.0 |
| Fasl cd95l signaling 0 5 0.0 1.0 |
| Triglyceride biosynthesis 0 7 0.0 1.0 |
| Fatty acyl coa biosynthesis 0 29 0.0 1.0 |
| Mrna editing 0 4 0.0 1.0 |
| Platelet adhesion to exposed collagen 0 7 0.0 1.0 |
| Processing of capped intronless pre mrna 1 29 0.694883587237712 0.7664238447790522 |
| Signaling by insulin receptor 3 45 1.3933621933621934 0.3781133452772955 |
| Insulin receptor signalling cascade 2 31 1.3444104560622914 0.451414074418919 |
| Signal attenuation 1 9 2.437122736418511 0.3629223192764827 |
| Purine salvage 0 12 0.0 1.0 |
| Ketone body metabolism 1 7 3.250167672702884 0.295760276625992 |
| Rna polymerase iii transcription 0 44 0.0 1.0 |
| Rna polymerase iii transcription termination 0 24 0.0 1.0 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 1 14 1.498993963782696 0.5041689495301098 |
| Tnf signaling 2 39 1.0528552746294682 0.5745348929819367 |
| Platelet activation signaling and aggregation 7 152 0.9392653978509726 0.61782242739709 |
| Response to elevated platelet cytosolic ca2 3 71 0.8582887700534759 0.6809989433277823 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0 8 0.0 1.0 |
| Transport of fatty acids 0 3 0.0 1.0 |
| Processing of intronless pre mrnas 1 21 0.9736418511066398 0.6509887274409705 |
| Slbp dependent processing of replication dependent histone pre mrnas 0 10 0.0 1.0 |
| Insulin receptor recycling 1 15 1.3917792469100316 0.5284199673110125 |
| Beta oxidation of butanoyl coa to acetyl coa 0 5 0.0 1.0 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0 5 0.0 1.0 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0 5 0.0 1.0 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0 6 0.0 1.0 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0 4 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation 0 33 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0 5 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0 9 0.0 1.0 |
| Synthesis of ketone bodies 0 6 0.0 1.0 |
| Rna polymerase iii transcription initiation from type 3 promoter 0 30 0.0 1.0 |
| Rna polymerase iii transcription initiation from type 1 promoter 0 31 0.0 1.0 |
| Platelet aggregation plug formation 1 20 1.0249920576088107 0.6330296848923271 |
| Interferon gamma signaling 3 51 1.2184343434343434 0.4573123863891611 |
| Creb3 factors activate genes 0 3 0.0 1.0 |
| Inlb mediated entry of listeria monocytogenes into host cell 1 15 1.3917792469100316 0.5284199673110125 |
| Met interacts with tns proteins 0 4 0.0 1.0 |
| Signaling by receptor tyrosine kinases 15 344 0.8843852064415035 0.712860532682285 |
| Signaling by nuclear receptors 4 178 0.4432034994648425 0.9770604635586934 |
| Signaling by erythropoietin 1 19 1.082047842611223 0.6141484764039431 |
| Loss of function of mecp2 in rett syndrome 0 12 0.0 1.0 |
| Transcriptional regulation by mecp2 1 45 0.4414669837205048 0.8954837048327721 |
| Interleukin 9 signaling 0 4 0.0 1.0 |
| Interleukin 35 signalling 0 9 0.0 1.0 |
| Signaling by tgfb family members 4 79 1.0389203778677465 0.5434263114578161 |
| Oas antiviral response 0 6 0.0 1.0 |
| Rhoa gtpase cycle 3 134 0.4426092990978487 0.9626407863616884 |
| Triglyceride metabolism 1 20 1.0249920576088107 0.6330296848923271 |
| Metabolism of cofactors 1 15 1.3917792469100316 0.5284199673110125 |
| Fatty acid metabolism 3 117 0.5095162147793727 0.930028751495062 |
| G beta gamma signalling through cdc42 0 14 0.0 1.0 |
| Lipid particle organization 0 1 0.0 1.0 |
| Glutamate and glutamine metabolism 0 14 0.0 1.0 |
| Interleukin 15 signaling 0 8 0.0 1.0 |
| Rab regulation of trafficking 5 107 0.9541423060096248 0.6044617178236004 |
| Interleukin 37 signaling 1 12 1.7719041521858423 0.451869757084416 |
| Extra nuclear estrogen signaling 3 47 1.3297520661157023 0.4048893372814988 |
| Rhou gtpase cycle 2 39 1.0528552746294682 0.5745348929819367 |
| Rhobtb2 gtpase cycle 1 22 0.9271821404618186 0.6680705567912797 |
| Rhoj gtpase cycle 1 55 0.3593412325806692 0.9368142124144576 |
| Rhog gtpase cycle 1 71 0.2767461914343202 0.9717865711961656 |
| Rhoh gtpase cycle 0 32 0.0 1.0 |
| Rhoq gtpase cycle 3 59 1.0435064935064935 0.5555158130103539 |
| Rhod gtpase cycle 0 50 0.0 1.0 |
| Rac2 gtpase cycle 1 81 0.2419014084507042 0.9829660504524428 |
| Rac1 gtpase cycle 2 152 0.2566666666666666 0.9958333175023044 |
| Cdc42 gtpase cycle 1 134 0.1447028032858807 0.9988354763739526 |
| Rhoc gtpase cycle 3 75 0.8102693602693603 0.7164849574682866 |
| Rhob gtpase cycle 1 69 0.2849449639010534 0.9687926182002238 |
| Rho gtpase cycle 12 387 0.6138600823045267 0.9693634090480014 |
| Signaling by notch3 0 35 0.0 1.0 |
| Robo receptors bind akap5 0 8 0.0 1.0 |
| Calnexin calreticulin cycle 0 23 0.0 1.0 |
| Er quality control compartment erqc 0 18 0.0 1.0 |
| Hdl remodeling 0 3 0.0 1.0 |
| Vldl clearance 0 4 0.0 1.0 |
| Plasma lipoprotein clearance 0 23 0.0 1.0 |
| Ldl remodeling 0 2 0.0 1.0 |
| Competing endogenous rnas cernas regulate pten translation 0 8 0.0 1.0 |
| Collagen chain trimerization 0 13 0.0 1.0 |
| Regulation of pten gene transcription 0 56 0.0 1.0 |
| Regulation of pten mrna translation 0 9 0.0 1.0 |
| Runx3 regulates notch signaling 0 11 0.0 1.0 |
| Runx3 regulates cdkn1a transcription 0 7 0.0 1.0 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 2 36 1.146110056925996 0.530799029376844 |
| Esr mediated signaling 4 136 0.5867991657465341 0.9048214189847896 |
| Aryl hydrocarbon receptor signalling 0 7 0.0 1.0 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 3 39 1.6265993265993266 0.2968056975451645 |
| Digestion 0 1 0.0 1.0 |
| Gaba synthesis release reuptake and degradation 1 12 1.7719041521858423 0.451869757084416 |
| Inla mediated entry of listeria monocytogenes into host cells 1 9 2.437122736418511 0.3629223192764827 |
| Listeria monocytogenes entry into host cells 2 21 2.05411714770798 0.2738488340493723 |
| Rab gefs exchange gtp for gdp on rabs 2 79 0.5038227901131127 0.904094104007335 |
| Met promotes cell motility 2 29 1.444295101553166 0.4175813594218437 |
| Met activates rap1 and rac1 1 11 1.9492957746478876 0.4236908718837023 |
| Regulation of pten localization 0 8 0.0 1.0 |
| Death receptor signalling 5 120 0.8451362554017109 0.7039844777501482 |
| Mitochondrial calcium ion transport 0 21 0.0 1.0 |
| Processing of smdt1 0 16 0.0 1.0 |
| Ldl clearance 0 17 0.0 1.0 |
| Chylomicron clearance 0 4 0.0 1.0 |
| Hdl clearance 0 2 0.0 1.0 |
| Chylomicron remodeling 0 4 0.0 1.0 |
| Plasma lipoprotein remodeling 0 12 0.0 1.0 |
| Plasma lipoprotein assembly 0 12 0.0 1.0 |
| Hdl assembly 0 6 0.0 1.0 |
| Assembly of active lpl and lipc lipase complexes 0 7 0.0 1.0 |
| Chylomicron assembly 0 5 0.0 1.0 |
| Digestion and absorption 0 1 0.0 1.0 |
| Aspartate and asparagine metabolism 0 7 0.0 1.0 |
| Tyrosine catabolism 0 2 0.0 1.0 |
| Metabolism of steroids 4 103 0.7850979429926799 0.7477210974081628 |
| Runx3 regulates bcl2l11 bim transcription 0 5 0.0 1.0 |
| Runx3 regulates p14 arf 1 11 1.9492957746478876 0.4236908718837023 |
| Runx3 regulates yap1 mediated transcription 0 6 0.0 1.0 |
| Runx3 regulates wnt signaling 0 8 0.0 1.0 |
| Cristae formation 1 27 0.7484909456740443 0.7417475603012252 |
| Bbsome mediated cargo targeting to cilium 0 18 0.0 1.0 |
| Activation of kainate receptors upon glutamate binding 1 16 1.298859825620389 0.5514871371697274 |
| Anchoring of the basal body to the plasma membrane 5 95 1.0827135451881902 0.4977755655278428 |
| Fgfr2b ligand binding and activation 0 2 0.0 1.0 |
| Fgfr2c ligand binding and activation 0 2 0.0 1.0 |
| Fgfr1c ligand binding and activation 0 2 0.0 1.0 |
| Fgfr3b ligand binding and activation 0 1 0.0 1.0 |
| Fgfr1b ligand binding and activation 0 2 0.0 1.0 |
| Fgfr1 ligand binding and activation 0 2 0.0 1.0 |
| Fgfr2 ligand binding and activation 0 2 0.0 1.0 |
| Fgfr3 ligand binding and activation 0 3 0.0 1.0 |
| Signaling by fgfr 2 57 0.7069648093841642 0.7746714005868853 |
| Heme degradation 0 7 0.0 1.0 |
| Heme biosynthesis 1 12 1.7719041521858423 0.451869757084416 |
| Metabolism of porphyrins 1 17 1.2175553319919517 0.5734281396877692 |
| Cellular hexose transport 0 6 0.0 1.0 |
| Signalling to p38 via rit and rin 0 3 0.0 1.0 |
| Signalling to erks 2 30 1.392569124423963 0.4346340509927128 |
| Ngf independant trka activation 0 1 0.0 1.0 |
| Activation of trka receptors 0 1 0.0 1.0 |
| Gap junction degradation 0 12 0.0 1.0 |
| Pre notch processing in golgi 1 13 1.6240778001341385 0.4786734551421467 |
| Pre notch expression and processing 2 50 0.8106518817204301 0.7090070314070043 |
| Synthesis of bile acids and bile salts 0 20 0.0 1.0 |
| Cobalamin cbl vitamin b12 transport and metabolism 0 13 0.0 1.0 |
| Pi3k events in erbb2 signaling 0 7 0.0 1.0 |
| Grb2 events in erbb2 signaling 0 7 0.0 1.0 |
| Pregnenolone biosynthesis 0 8 0.0 1.0 |
| Metabolism of steroid hormones 0 12 0.0 1.0 |
| Vegf ligand receptor interactions 0 2 0.0 1.0 |
| Signaling by vegf 4 87 0.93800302424272 0.6203455265540181 |
| Bile acid and bile salt metabolism 0 22 0.0 1.0 |
| Regulation of beta cell development 0 22 0.0 1.0 |
| Synthesis of bile acids and bile salts via 27 hydroxycholesterol 0 7 0.0 1.0 |
| P75 ntr receptor mediated signalling 3 81 0.7474747474747475 0.7638761720595773 |
| Regulated proteolysis of p75ntr 0 11 0.0 1.0 |
| P75ntr negatively regulates cell cycle via sc1 0 5 0.0 1.0 |
| Nrage signals death through jnk 0 47 0.0 1.0 |
| P75ntr signals via nf kb 0 14 0.0 1.0 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0 13 0.0 1.0 |
| Estrogen biosynthesis 0 2 0.0 1.0 |
| Androgen biosynthesis 0 2 0.0 1.0 |
| Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0 5 0.0 1.0 |
| Metabolism of folate and pterines 0 15 0.0 1.0 |
| Synthesis of ip2 ip and ins in the cytosol 1 12 1.7719041521858423 0.451869757084416 |
| Fgfr2 mutant receptor activation 0 18 0.0 1.0 |
| Interactions of vpr with host cellular proteins 2 37 1.1132488479262672 0.5457127493648501 |
| Assembly of the hiv virion 1 15 1.3917792469100316 0.5284199673110125 |
| Plasma lipoprotein assembly remodeling and clearance 0 40 0.0 1.0 |
| Activation of c3 and c5 0 1 0.0 1.0 |
| Glutathione synthesis and recycling 1 8 2.785570566254671 0.3301808657155594 |
| Apc c cdc20 mediated degradation of cyclin b 1 23 0.8849460398756174 0.6843179386047307 |
| Alternative complement activation 0 1 0.0 1.0 |
| Telomere extension by telomerase 2 21 2.05411714770798 0.2738488340493723 |
| P38mapk events 1 13 1.6240778001341385 0.4786734551421467 |
| Arms mediated activation 0 5 0.0 1.0 |
| Signaling by tgf beta receptor complex 4 67 1.23835229098387 0.4152240471893244 |
| Regulation of glucokinase by glucokinase regulatory protein 1 31 0.6484238765928907 0.788746565408226 |
| Adenylate cyclase activating pathway 0 3 0.0 1.0 |
| Prolonged erk activation events 1 12 1.7719041521858423 0.451869757084416 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 2 57 0.7069648093841642 0.7746714005868853 |
| Ticam1 rip1 mediated ikk complex recruitment 0 16 0.0 1.0 |
| Toll like receptor cascades 4 103 0.7850979429926799 0.7477210974081628 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 1 20 1.0249920576088107 0.6330296848923271 |
| Phosphorylation of the apc c 1 20 1.0249920576088107 0.6330296848923271 |
| Phosphorylation of emi1 0 6 0.0 1.0 |
| Unwinding of dna 1 12 1.7719041521858423 0.451869757084416 |
| Fgfr1 mutant receptor activation 1 22 0.9271821404618186 0.6680705567912797 |
| Signaling by cytosolic fgfr1 fusion mutants 1 18 1.1458160729080364 0.5942978505128852 |
| Cytosolic sensors of pathogen associated dna 0 56 0.0 1.0 |
| Sting mediated induction of host immune responses 0 10 0.0 1.0 |
| Egfr downregulation 1 22 0.9271821404618186 0.6680705567912797 |
| Nef mediated cd8 down regulation 0 6 0.0 1.0 |
| Acetylcholine binding and downstream events 0 2 0.0 1.0 |
| Norepinephrine neurotransmitter release cycle 1 12 1.7719041521858423 0.451869757084416 |
| Organelle biogenesis and maintenance 15 268 1.159379372989959 0.3303219257202697 |
| Serotonin neurotransmitter release cycle 1 14 1.498993963782696 0.5041689495301098 |
| Nuclear import of rev protein 1 34 0.589293335772209 0.8183019856004505 |
| Apobec3g mediated resistance to hiv 1 infection 0 4 0.0 1.0 |
| Shc1 events in egfr signaling 0 7 0.0 1.0 |
| Apc cdc20 mediated degradation of nek2a 2 25 1.6961781206171107 0.3470060894740981 |
| Chondroitin sulfate dermatan sulfate metabolism 0 32 0.0 1.0 |
| Signaling by egfr 3 40 1.5824733824733823 0.3103681353614002 |
| Retrograde neurotrophin signalling 0 12 0.0 1.0 |
| Interactions of rev with host cellular proteins 1 37 0.5400178850883076 0.8437295850039954 |
| Rip mediated nfkb activation via zbp1 0 16 0.0 1.0 |
| Neurotoxicity of clostridium toxins 0 8 0.0 1.0 |
| Biotin transport and metabolism 0 11 0.0 1.0 |
| Vitamin d calciferol metabolism 0 8 0.0 1.0 |
| Endogenous sterols 0 12 0.0 1.0 |
| Miscellaneous substrates 0 2 0.0 1.0 |
| Phase i functionalization of compounds 1 39 0.5114899925871016 0.8586757123257109 |
| Cytochrome p450 arranged by substrate type 0 15 0.0 1.0 |
| Gene silencing by rna 2 75 0.5316504639858595 0.8874544722584757 |
| Tie2 signaling 1 12 1.7719041521858423 0.451869757084416 |
| Basigin interactions 0 16 0.0 1.0 |
| Regulation of gene expression in early pancreatic precursor cells 0 3 0.0 1.0 |
| Regulation of gene expression in beta cells 0 12 0.0 1.0 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0 10 0.0 1.0 |
| Glutamate neurotransmitter release cycle 1 17 1.2175553319919517 0.5734281396877692 |
| Metabolism of amine derived hormones 0 1 0.0 1.0 |
| Nf kb is activated and signals survival 0 11 0.0 1.0 |
| P75ntr recruits signalling complexes 0 11 0.0 1.0 |
| Nrif signals cell death from the nucleus 0 14 0.0 1.0 |
| Cell death signalling via nrage nrif and nade 2 63 0.6370306716023268 0.8202778956166314 |
| Linoleic acid la metabolism 0 7 0.0 1.0 |
| Eicosanoids 0 1 0.0 1.0 |
| Xenobiotics 0 4 0.0 1.0 |
| Cyp2e1 reactions 0 1 0.0 1.0 |
| Epigenetic regulation of gene expression 1 102 0.1911867243062334 0.9941061902250166 |
| Transcriptional activation of mitochondrial biogenesis 1 51 0.3882494969818914 0.9227191737187296 |
| Hyaluronan biosynthesis and export 0 1 0.0 1.0 |
| Hyaluronan metabolism 1 9 2.437122736418511 0.3629223192764827 |
| Synthesis of 16 20 hydroxyeicosatetraenoic acids hete 0 1 0.0 1.0 |
| Ubiquinol biosynthesis 1 7 3.250167672702884 0.295760276625992 |
| Synthesis of 15 eicosatetraenoic acid derivatives 0 3 0.0 1.0 |
| Arachidonic acid metabolism 0 18 0.0 1.0 |
| Synthesis of 12 eicosatetraenoic acid derivatives 0 2 0.0 1.0 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 0 12 0.0 1.0 |
| Synthesis of lipoxins lx 0 1 0.0 1.0 |
| Synthesis of 5 eicosatetraenoic acids 0 3 0.0 1.0 |
| Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet 0 1 0.0 1.0 |
| Molecules associated with elastic fibres 0 18 0.0 1.0 |
| Egfr interacts with phospholipase c gamma 0 2 0.0 1.0 |
| Dopamine neurotransmitter release cycle 1 18 1.1458160729080364 0.5942978505128852 |
| Prc2 methylates histones and dna 0 23 0.0 1.0 |
| Activated notch1 transmits signal to the nucleus 0 21 0.0 1.0 |
| Notch1 intracellular domain regulates transcription 2 39 1.0528552746294682 0.5745348929819367 |
| Synthesis of leukotrienes lt and eoxins ex 0 4 0.0 1.0 |
| Coenzyme a biosynthesis 1 8 2.785570566254671 0.3301808657155594 |
| Regulation of pyruvate dehydrogenase pdh complex 0 16 0.0 1.0 |
| Nostrin mediated enos trafficking 0 3 0.0 1.0 |
| Trans golgi network vesicle budding 3 69 0.8844811753902663 0.6620606952846602 |
| Creb phosphorylation 0 7 0.0 1.0 |
| Negative regulation of the pi3k akt network 4 62 1.3458048303783332 0.3591951689526639 |
| Vitamin b5 pantothenate metabolism 1 13 1.6240778001341385 0.4786734551421467 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0 26 0.0 1.0 |
| Erk mapk targets 1 20 1.0249920576088107 0.6330296848923271 |
| Nuclear events kinase and transcription factor activation 2 42 0.9735887096774194 0.6152256119482173 |
| Akt phosphorylates targets in the nucleus 0 9 0.0 1.0 |
| Akt phosphorylates targets in the cytosol 1 14 1.498993963782696 0.5041689495301098 |
| Pi3k akt activation 1 7 3.250167672702884 0.295760276625992 |
| Signaling by notch2 0 22 0.0 1.0 |
| Signaling by notch1 2 56 0.720131421744325 0.7661546402852099 |
| Nicotinamide salvaging 1 11 1.9492957746478876 0.4236908718837023 |
| A tetrasaccharide linker sequence is required for gag synthesis 0 16 0.0 1.0 |
| Metabolism of vitamins and cofactors 8 134 1.2402980239714934 0.3315926653176778 |
| Vitamin b1 thiamin metabolism 0 5 0.0 1.0 |
| Nicotinate metabolism 1 18 1.1458160729080364 0.5942978505128852 |
| Signaling by bmp 0 15 0.0 1.0 |
| Signaling by alk 1 19 1.082047842611223 0.6141484764039431 |
| Wnt mediated activation of dvl 1 8 2.785570566254671 0.3301808657155594 |
| Formation of the beta catenin tcf transactivating complex 1 38 0.5253684267768775 0.8513900502920986 |
| Enos activation 0 7 0.0 1.0 |
| Yap1 and wwtr1 taz stimulated gene expression 0 10 0.0 1.0 |
| Role of phospholipids in phagocytosis 0 16 0.0 1.0 |
| Signaling by hippo 1 21 0.9736418511066398 0.6509887274409705 |
| Erks are inactivated 1 11 1.9492957746478876 0.4236908718837023 |
| Calcineurin activates nfat 1 8 2.785570566254671 0.3301808657155594 |
| Generation of second messenger molecules 1 11 1.9492957746478876 0.4236908718837023 |
| Cs ds degradation 0 7 0.0 1.0 |
| Microrna mirna biogenesis 1 24 0.8463826436882163 0.6997715576731252 |
| Hs gag degradation 0 17 0.0 1.0 |
| Dermatan sulfate biosynthesis 0 6 0.0 1.0 |
| Chondroitin sulfate biosynthesis 0 12 0.0 1.0 |
| Keratan sulfate degradation 0 6 0.0 1.0 |
| Keratan sulfate biosynthesis 0 11 0.0 1.0 |
| Metabolism of angiotensinogen to angiotensins 0 8 0.0 1.0 |
| Assembly of collagen fibrils and other multimeric structures 0 28 0.0 1.0 |
| Metabolism of nitric oxide nos3 activation and regulation 0 10 0.0 1.0 |
| G protein activation 0 13 0.0 1.0 |
| Hs gag biosynthesis 0 17 0.0 1.0 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 2 42 0.9735887096774194 0.6152256119482173 |
| Nod1 2 signaling pathway 1 30 0.6708527024214251 0.7778648721483832 |
| Viral messenger rna synthesis 1 44 0.4517804501427168 0.8900922489783374 |
| Mitochondrial iron sulfur cluster biogenesis 0 12 0.0 1.0 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0 16 0.0 1.0 |
| Transcription of e2f targets under negative control by dream complex 1 19 1.082047842611223 0.6141484764039431 |
| Downregulation of erbb2 erbb3 signaling 0 10 0.0 1.0 |
| Grb7 events in erbb2 signaling 0 2 0.0 1.0 |
| Acrosome reaction and sperm oocyte membrane binding 0 1 0.0 1.0 |
| Sperm motility and taxes 0 1 0.0 1.0 |
| Tandem pore domain potassium channels 0 2 0.0 1.0 |
| Voltage gated potassium channels 0 2 0.0 1.0 |
| Potassium channels 0 15 0.0 1.0 |
| Inwardly rectifying k channels 0 12 0.0 1.0 |
| Mitochondrial protein import 1 59 0.3344203149934087 0.948342704372086 |
| Interleukin 7 signaling 0 13 0.0 1.0 |
| Downregulation of erbb4 signaling 1 7 3.250167672702884 0.295760276625992 |
| Nuclear signaling by erbb4 1 18 1.1458160729080364 0.5942978505128852 |
| Shc1 events in erbb4 signaling 0 6 0.0 1.0 |
| Pi3k events in erbb4 signaling 0 2 0.0 1.0 |
| Rora activates gene expression 0 17 0.0 1.0 |
| Bmal1 clock npas2 activates circadian gene expression 0 20 0.0 1.0 |
| Abc transporters in lipid homeostasis 0 7 0.0 1.0 |
| Elevation of cytosolic ca2 levels 0 6 0.0 1.0 |
| Reversible hydration of carbon dioxide 0 2 0.0 1.0 |
| Collagen formation 0 44 0.0 1.0 |
| Extracellular matrix organization 3 131 0.453125 0.958183920936633 |
| Degradation of the extracellular matrix 2 56 0.720131421744325 0.7661546402852099 |
| Reproduction 4 57 1.4735314338094874 0.3030756698351194 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0 7 0.0 1.0 |
| Alpha defensins 0 1 0.0 1.0 |
| Defensins 0 1 0.0 1.0 |
| Shc1 events in erbb2 signaling 0 13 0.0 1.0 |
| Collagen degradation 0 21 0.0 1.0 |
| The citric acid tca cycle and respiratory electron transport 4 160 0.49527665317139 0.9569241160711732 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 2 21 2.05411714770798 0.2738488340493723 |
| Formation of fibrin clot clotting cascade 0 9 0.0 1.0 |
| Common pathway of fibrin clot formation 0 5 0.0 1.0 |
| Intrinsic pathway of fibrin clot formation 0 7 0.0 1.0 |
| Extrinsic pathway of fibrin clot formation 0 1 0.0 1.0 |
| Caspase activation via death receptors in the presence of ligand 0 11 0.0 1.0 |
| Activation of puma and translocation to mitochondria 0 8 0.0 1.0 |
| Regulation of signaling by nodal 0 3 0.0 1.0 |
| Acyl chain remodelling of pc 0 9 0.0 1.0 |
| Erythrocytes take up oxygen and release carbon dioxide 0 1 0.0 1.0 |
| Endosomal vacuolar pathway 0 10 0.0 1.0 |
| Formation of rna pol ii elongation complex 3 58 1.0625895316804408 0.5438179728252587 |
| Neurotransmitter clearance 0 3 0.0 1.0 |
| Neurotransmitter release cycle 1 30 0.6708527024214251 0.7778648721483832 |
| Presynaptic depolarization and calcium channel opening 0 4 0.0 1.0 |
| Electric transmission across gap junctions 0 2 0.0 1.0 |
| G protein mediated events 2 40 1.0250424448217317 0.5884384065253555 |
| Ca dependent events 0 26 0.0 1.0 |
| Camk iv mediated phosphorylation of creb 0 8 0.0 1.0 |
| Pka mediated phosphorylation of creb 0 13 0.0 1.0 |
| Formation of apoptosome 1 11 1.9492957746478876 0.4236908718837023 |
| Release of apoptotic factors from the mitochondria 0 6 0.0 1.0 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0 8 0.0 1.0 |
| Activation of noxa and translocation to mitochondria 0 5 0.0 1.0 |
| Activation of bad and translocation to mitochondria 0 16 0.0 1.0 |
| Displacement of dna glycosylase by apex1 1 8 2.785570566254671 0.3301808657155594 |
| Recognition and association of dna glycosylase with site containing an affected purine 0 16 0.0 1.0 |
| Mapk3 erk1 activation 1 8 2.785570566254671 0.3301808657155594 |
| Irs mediated signalling 1 26 0.7785110663983903 0.7284504433708964 |
| Mapk1 erk2 activation 1 7 3.250167672702884 0.295760276625992 |
| Sos mediated signalling 0 7 0.0 1.0 |
| Formation of the early elongation complex 2 33 1.257414151925078 0.4841018564616677 |
| Cross presentation of particulate exogenous antigens phagosomes 0 3 0.0 1.0 |
| Signaling by erbb4 1 36 0.5555044553032481 0.8356750759447882 |
| Constitutive signaling by ligand responsive egfr cancer variants 0 17 0.0 1.0 |
| Regulation of gene expression by hypoxia inducible factor 0 5 0.0 1.0 |
| Signaling by erbb2 in cancer 0 17 0.0 1.0 |
| Signaling by erbb2 3 37 1.722638146167558 0.2698089294696847 |
| Signaling by fgfr in disease 1 48 0.41315980992337 0.9101252243720072 |
| Ros and rns production in phagocytes 1 16 1.298859825620389 0.5514871371697274 |
| Erythrocytes take up carbon dioxide and release oxygen 0 4 0.0 1.0 |
| Meiotic synapsis 1 31 0.6484238765928907 0.788746565408226 |
| Signaling by nodal 0 12 0.0 1.0 |
| Antiviral mechanism by ifn stimulated genes 3 73 0.8335930735930736 0.6991384425989577 |
| Activation of ras in b cells 0 3 0.0 1.0 |
| Gpvi mediated activation cascade 2 21 2.05411714770798 0.2738488340493723 |
| Disinhibition of snare formation 0 4 0.0 1.0 |
| Effects of pip2 hydrolysis 0 17 0.0 1.0 |
| Activation of bh3 only proteins 1 29 0.694883587237712 0.7664238447790522 |
| E2f enabled inhibition of pre replication complex formation 1 10 2.1661077576570533 0.3940663935801297 |
| Fertilization 0 3 0.0 1.0 |
| Acyl chain remodeling of cl 0 5 0.0 1.0 |
| Acyl chain remodelling of ps 0 9 0.0 1.0 |
| Acyl chain remodelling of pe 0 8 0.0 1.0 |
| Synthesis of pips at the late endosome membrane 1 10 2.1661077576570533 0.3940663935801297 |
| Synthesis of pips at the plasma membrane 2 47 0.8649641577060931 0.6762960356823782 |
| Regulation of cholesterol biosynthesis by srebp srebf 2 55 0.7337948874010956 0.7573597618825716 |
| Collagen biosynthesis and modifying enzymes 0 30 0.0 1.0 |
| The role of nef in hiv 1 replication and disease pathogenesis 0 20 0.0 1.0 |
| Nef and signal transduction 0 4 0.0 1.0 |
| Nef mediated downregulation of mhc class i complex cell surface expression 0 9 0.0 1.0 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0 16 0.0 1.0 |
| 2 ltr circle formation 0 7 0.0 1.0 |
| Pka activation in glucagon signalling 0 12 0.0 1.0 |
| Signaling by egfr in cancer 0 17 0.0 1.0 |
| Heparan sulfate heparin hs gag metabolism 0 32 0.0 1.0 |
| Keratan sulfate keratin metabolism 0 17 0.0 1.0 |
| Chrebp activates metabolic gene expression 0 8 0.0 1.0 |
| Integration of energy metabolism 4 71 1.1639373980300924 0.4592640961404083 |
| Ampk inhibits chrebp transcriptional activation activity 1 7 3.250167672702884 0.295760276625992 |
| Triglyceride catabolism 1 13 1.6240778001341385 0.4786734551421467 |
| Sphingolipid de novo biosynthesis 0 29 0.0 1.0 |
| Glycosphingolipid metabolism 0 33 0.0 1.0 |
| Myd88 independent tlr4 cascade 4 78 1.0530692635955794 0.5332612412749236 |
| Mitochondrial uncoupling 0 1 0.0 1.0 |
| Ns1 mediated effects on host pathways 2 40 1.0250424448217317 0.5884384065253555 |
| Export of viral ribonucleoproteins from nucleus 1 32 0.627442071785552 0.7990962171858123 |
| Toll like receptor tlr1 tlr2 cascade 2 70 0.57103889943074 0.8629026159544475 |
| Toll like receptor 9 tlr9 cascade 2 75 0.5316504639858595 0.8874544722584757 |
| Trafficking and processing of endosomal tlr 0 8 0.0 1.0 |
| The fatty acid cycling model 0 1 0.0 1.0 |
| Nef mediated cd4 down regulation 0 7 0.0 1.0 |
| Hiv elongation arrest and recovery 2 32 1.299462365591398 0.4679073600042346 |
| Glucagon signaling in metabolic regulation 0 21 0.0 1.0 |
| Abortive elongation of hiv 1 transcript in the absence of tat 1 23 0.8849460398756174 0.6843179386047307 |
| Hiv transcription elongation 3 42 1.501010101010101 0.3375295111799605 |
| Hiv transcription initiation 1 45 0.4414669837205048 0.8954837048327721 |
| Signalling to ras 1 16 1.298859825620389 0.5514871371697274 |
| Terminal pathway of complement 0 1 0.0 1.0 |
| Initial triggering of complement 0 1 0.0 1.0 |
| Complement cascade 0 10 0.0 1.0 |
| Signaling by ntrks 6 102 1.2197662601626016 0.3806937467899882 |
| The activation of arylsulfatases 0 8 0.0 1.0 |
| Transcription of the hiv genome 4 67 1.23835229098387 0.4152240471893244 |
| Pka mediated phosphorylation of key metabolic factors 0 4 0.0 1.0 |
| Formation of atp by chemiosmotic coupling 1 14 1.498993963782696 0.5041689495301098 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 3 116 0.5140788415124699 0.9274627654026104 |
| Glucuronidation 0 4 0.0 1.0 |
| G0 and early g1 2 26 1.6253360215053765 0.3649620055651655 |
| Signaling by activin 0 9 0.0 1.0 |
| Cell cell communication 4 79 1.0389203778677465 0.5434263114578161 |
| Meiosis 4 54 1.5624291497975709 0.2698738667135572 |
| Dag and ip3 signaling 0 30 0.0 1.0 |
| Phospholipid metabolism 4 156 0.5085233326230556 0.9506408692496164 |
| Pi metabolism 3 71 0.8582887700534759 0.6809989433277823 |
| Elastic fibre formation 0 23 0.0 1.0 |
| Synthesis of pi 0 5 0.0 1.0 |
| Glycerophospholipid biosynthesis 1 86 0.2275535566339211 0.9867668949235924 |
| Synthesis of pc 1 22 0.9271821404618186 0.6680705567912797 |
| Synthesis of pa 0 25 0.0 1.0 |
| Synthesis of pg 0 8 0.0 1.0 |
| Hydrolysis of lpc 0 3 0.0 1.0 |
| Acyl chain remodelling of pg 0 7 0.0 1.0 |
| Acyl chain remodelling of pi 0 4 0.0 1.0 |
| Acyl chain remodeling of dag and tag 0 2 0.0 1.0 |
| Synthesis of pe 0 12 0.0 1.0 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 1 8 2.785570566254671 0.3301808657155594 |
| Fibronectin matrix formation 0 3 0.0 1.0 |
| Mitochondrial biogenesis 3 85 0.7107169253510717 0.7917535393029798 |
| Post translational modification synthesis of gpi anchored proteins 0 32 0.0 1.0 |
| Glycosaminoglycan metabolism 3 70 0.8711895070104025 0.6716298652770193 |
| Attachment of gpi anchor to upar 0 7 0.0 1.0 |
| Synthesis of glycosylphosphatidylinositol gpi 0 12 0.0 1.0 |
| Golgi cisternae pericentriolar stack reorganization 0 14 0.0 1.0 |
| Integration of provirus 1 9 2.437122736418511 0.3629223192764827 |
| Budding and maturation of hiv virion 1 27 0.7484909456740443 0.7417475603012252 |
| Hiv life cycle 8 144 1.1478991596638657 0.4063305104597019 |
| Polo like kinase mediated events 0 16 0.0 1.0 |
| Degradation of cysteine and homocysteine 1 12 1.7719041521858423 0.451869757084416 |
| Irf3 mediated activation of type 1 ifn 0 3 0.0 1.0 |
| Zbp1 dai mediated induction of type i ifns 0 18 0.0 1.0 |
| Gamma carboxylation transport and amino terminal cleavage of proteins 0 5 0.0 1.0 |
| Removal of aminoterminal propeptides from gamma carboxylated proteins 0 4 0.0 1.0 |
| Recycling of bile acids and salts 0 6 0.0 1.0 |
| Activation of matrix metalloproteinases 0 6 0.0 1.0 |
| Transport of mature mrnas derived from intronless transcripts 1 43 0.4625850340136054 0.8844232629609907 |
| Transport of the slbp dependant mature mrna 1 36 0.5555044553032481 0.8356750759447882 |
| Sulfide oxidation to sulfate 0 5 0.0 1.0 |
| Cargo trafficking to the periciliary membrane 2 43 0.949744295830055 0.6281100642676263 |
| Integrin cell surface interactions 0 37 0.0 1.0 |
| Abacavir transmembrane transport 0 2 0.0 1.0 |
| Gp1b ix v activation signalling 1 7 3.250167672702884 0.295760276625992 |
| Mrna decay by 5 to 3 exoribonuclease 0 15 0.0 1.0 |
| Mrna decay by 3 to 5 exoribonuclease 0 16 0.0 1.0 |
| Deadenylation of mrna 2 26 1.6253360215053765 0.3649620055651655 |
| Deadenylation dependent mrna decay 2 57 0.7069648093841642 0.7746714005868853 |
| Thromboxane signalling through tp receptor 0 15 0.0 1.0 |
| Role of abl in robo slit signaling 0 9 0.0 1.0 |
| Organic anion transporters 0 3 0.0 1.0 |
| Inactivation of cdc42 and rac1 0 8 0.0 1.0 |
| Regulation of commissural axon pathfinding by slit and robo 1 7 3.250167672702884 0.295760276625992 |
| Activation of rac1 1 12 1.7719041521858423 0.451869757084416 |
| Sphingolipid metabolism 0 62 0.0 1.0 |
| Sodium coupled phosphate cotransporters 0 2 0.0 1.0 |
| Multifunctional anion exchangers 0 3 0.0 1.0 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0 27 0.0 1.0 |
| Sirt1 negatively regulates rrna expression 0 18 0.0 1.0 |
| Small interfering rna sirna biogenesis 1 9 2.437122736418511 0.3629223192764827 |
| Vasopressin regulates renal water homeostasis via aquaporins 0 25 0.0 1.0 |
| Passive transport by aquaporins 0 1 0.0 1.0 |
| Lysosome vesicle biogenesis 0 32 0.0 1.0 |
| Golgi associated vesicle biogenesis 2 55 0.7337948874010956 0.7573597618825716 |
| Type i hemidesmosome assembly 0 9 0.0 1.0 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 0 25 0.0 1.0 |
| Aquaporin mediated transport 0 26 0.0 1.0 |
| Smooth muscle contraction 0 28 0.0 1.0 |
| Interaction between l1 and ankyrins 1 12 1.7719041521858423 0.451869757084416 |
| Rsk activation 0 7 0.0 1.0 |
| Ras activation upon ca2 influx through nmda receptor 0 13 0.0 1.0 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0 21 0.0 1.0 |
| Cation coupled chloride cotransporters 0 4 0.0 1.0 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0 7 0.0 1.0 |
| Na cl dependent neurotransmitter transporters 0 4 0.0 1.0 |
| Zinc influx into cells by the slc39 gene family 0 7 0.0 1.0 |
| Depolymerisation of the nuclear lamina 0 16 0.0 1.0 |
| Binding of tcf lef ctnnb1 to target gene promoters 0 7 0.0 1.0 |
| Unblocking of nmda receptors glutamate binding and activation 0 9 0.0 1.0 |
| Zinc efflux and compartmentalization by the slc30 family 0 5 0.0 1.0 |
| Zinc transporters 0 12 0.0 1.0 |
| Proton coupled monocarboxylate transport 0 4 0.0 1.0 |
| Creb1 phosphorylation through the activation of adenylate cyclase 0 9 0.0 1.0 |
| Synthesis of gdp mannose 0 5 0.0 1.0 |
| Arachidonate production from dag 0 4 0.0 1.0 |
| Sodium calcium exchangers 0 3 0.0 1.0 |
| Nucleotide like purinergic receptors 0 1 0.0 1.0 |
| P2y receptors 0 1 0.0 1.0 |
| Trafficking of glur2 containing ampa receptors 0 11 0.0 1.0 |
| Other semaphorin interactions 0 7 0.0 1.0 |
| Sema4d mediated inhibition of cell attachment and migration 1 8 2.785570566254671 0.3301808657155594 |
| G alpha 12 13 signalling events 2 57 0.7069648093841642 0.7746714005868853 |
| G alpha q signalling events 1 66 0.2981891348088531 0.9636969678977702 |
| Sumoylation of intracellular receptors 0 18 0.0 1.0 |
| Ca2 pathway 1 45 0.4414669837205048 0.8954837048327721 |
| Sumoylation of sumoylation proteins 1 35 0.5719020002367144 0.8272062968755179 |
| Sialic acid metabolism 1 16 1.298859825620389 0.5514871371697274 |
| Sema4d in semaphorin signaling 2 23 1.8581029185867897 0.3106281566010752 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0 9 0.0 1.0 |
| Incretin synthesis secretion and inactivation 0 14 0.0 1.0 |
| Free fatty acids regulate insulin secretion 1 8 2.785570566254671 0.3301808657155594 |
| Circadian clock 2 55 0.7337948874010956 0.7573597618825716 |
| Regulation of lipid metabolism by pparalpha 1 95 0.2055738687443812 0.991602595896356 |
| Reduction of cytosolic ca levels 1 7 3.250167672702884 0.295760276625992 |
| Platelet calcium homeostasis 1 13 1.6240778001341385 0.4786734551421467 |
| Cgmp effects 0 7 0.0 1.0 |
| G alpha s signalling events 2 37 1.1132488479262672 0.5457127493648501 |
| Metal ion slc transporters 0 15 0.0 1.0 |
| Slc mediated transmembrane transport 1 101 0.1931187122736418 0.9938003532891208 |
| Transport of vitamins nucleosides and related molecules 0 21 0.0 1.0 |
| Transport of inorganic cations anions and amino acids oligopeptides 1 44 0.4517804501427168 0.8900922489783374 |
| Bicarbonate transporters 0 4 0.0 1.0 |
| Transport of bile salts and organic acids metal ions and amine compounds 0 32 0.0 1.0 |
| Regulation of insulin secretion 2 48 0.8460729312762973 0.6875196253461657 |
| Synthesis secretion and deacylation of ghrelin 0 5 0.0 1.0 |
| Sodium proton exchangers 0 4 0.0 1.0 |
| Cell cell junction organization 0 31 0.0 1.0 |
| Glucagon type ligand receptors 0 13 0.0 1.0 |
| Tight junction interactions 0 11 0.0 1.0 |
| Lysosphingolipid and lpa receptors 0 3 0.0 1.0 |
| Ncam1 interactions 1 15 1.3917792469100316 0.5284199673110125 |
| Adherens junctions interactions 0 18 0.0 1.0 |
| Role of second messengers in netrin 1 signaling 0 3 0.0 1.0 |
| G alpha z signalling events 1 28 0.720694537595946 0.7543947935478624 |
| Adp signalling through p2y purinoceptor 1 1 17 1.2175553319919517 0.5734281396877692 |
| Nectin necl trans heterodimerization 0 5 0.0 1.0 |
| Adrenaline noradrenaline inhibits insulin secretion 1 16 1.298859825620389 0.5514871371697274 |
| Cell extracellular matrix interactions 1 16 1.298859825620389 0.5514871371697274 |
| Cell junction organization 1 54 0.3661592194677499 0.9335514042389416 |
| Ra biosynthesis pathway 0 9 0.0 1.0 |
| Release of hh np from the secreting cell 0 2 0.0 1.0 |
| Signaling by retinoic acid 0 26 0.0 1.0 |
| Tnfr1 induced nfkappab signaling pathway 2 28 1.5 0.4002722624509632 |
| Regulation of tnfr1 signaling 2 31 1.3444104560622914 0.451414074418919 |
| Tnfr1 induced proapoptotic signaling 1 13 1.6240778001341385 0.4786734551421467 |
| Signaling by rnf43 mutants 0 4 0.0 1.0 |
| Signaling by lrp5 mutants 0 2 0.0 1.0 |
| Uptake and actions of bacterial toxins 0 23 0.0 1.0 |
| Uptake and function of diphtheria toxin 0 5 0.0 1.0 |
| Dna methylation 0 14 0.0 1.0 |
| N glycan trimming in the er and calnexin calreticulin cycle 0 32 0.0 1.0 |
| Diseases of immune system 0 15 0.0 1.0 |
| Myogenesis 0 22 0.0 1.0 |
| Toxicity of botulinum toxin type d botd 0 3 0.0 1.0 |
| Negative epigenetic regulation of rrna expression 1 61 0.3232059020791415 0.9532938015877442 |
| B wich complex positively regulates rrna expression 0 45 0.0 1.0 |
| Mitochondrial translation 2 93 0.4256912442396313 0.9459148761129126 |
| Negative regulation of tcf dependent signaling by dvl interacting proteins 0 5 0.0 1.0 |
| Diseases of mismatch repair mmr 0 5 0.0 1.0 |
| Organic cation transport 0 3 0.0 1.0 |
| Slc transporter disorders 1 54 0.3661592194677499 0.9335514042389416 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 1 60 0.3287180711386966 0.9508804702995598 |
| Diseases associated with glycosylation precursor biosynthesis 1 16 1.298859825620389 0.5514871371697274 |
| Clec7a dectin 1 induces nfat activation 0 10 0.0 1.0 |
| Irak4 deficiency tlr2 4 0 4 0.0 1.0 |
| Ikba variant leads to eda id 0 7 0.0 1.0 |
| Piwi interacting rna pirna biogenesis 0 16 0.0 1.0 |
| Metabolic disorders of biological oxidation enzymes 0 13 0.0 1.0 |
| Positive epigenetic regulation of rrna expression 0 60 0.0 1.0 |
| Ion homeostasis 1 31 0.6484238765928907 0.788746565408226 |
| Transcriptional regulation by small rnas 1 57 0.3464357574015522 0.9428679300522907 |
| Phase 2 plateau phase 0 3 0.0 1.0 |
| Phase 0 rapid depolarisation 0 6 0.0 1.0 |
| Cardiac conduction 1 43 0.4625850340136054 0.8844232629609907 |
| Phase 3 rapid repolarisation 0 1 0.0 1.0 |
| Phase 4 resting membrane potential 0 2 0.0 1.0 |
| Metabolism of lipids 14 508 0.5389299695519791 0.9948126063064266 |
| Organic cation anion zwitterion transport 0 3 0.0 1.0 |
| Physiological factors 0 6 0.0 1.0 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 1 7 3.250167672702884 0.295760276625992 |
| Miscellaneous transport and binding events 0 17 0.0 1.0 |
| Vegfr2 mediated vascular permeability 0 22 0.0 1.0 |
| Sumoylation of chromatin organization proteins 1 58 0.3403226375798651 0.9456741013414218 |
| Transcriptional regulation of pluripotent stem cells 0 16 0.0 1.0 |
| Interleukin 2 family signaling 0 21 0.0 1.0 |
| Ionotropic activity of kainate receptors 0 3 0.0 1.0 |
| Ksrp khsrp binds and destabilizes mrna 0 17 0.0 1.0 |
| Hur elavl1 binds and stabilizes mrna 0 7 0.0 1.0 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 0 17 0.0 1.0 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 0 17 0.0 1.0 |
| Activation of the ap 1 family of transcription factors 0 8 0.0 1.0 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0 18 0.0 1.0 |
| Activated tak1 mediates p38 mapk activation 0 20 0.0 1.0 |
| Mapk targets nuclear events mediated by map kinases 1 27 0.7484909456740443 0.7417475603012252 |
| Interleukin 1 processing 0 3 0.0 1.0 |
| Interleukin 17 signaling 2 57 0.7069648093841642 0.7746714005868853 |
| Neurofascin interactions 0 6 0.0 1.0 |
| Chl1 interactions 0 7 0.0 1.0 |
| Nrcam interactions 0 7 0.0 1.0 |
| Thrombin signalling through proteinase activated receptors pars 1 21 0.9736418511066398 0.6509887274409705 |
| Sumoylation of rna binding proteins 1 47 0.4221852856268043 0.9054876076980892 |
| Sumoylation of dna replication proteins 2 46 0.8847140762463344 0.6647468144888726 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 2 24 1.7734604105571847 0.3288847005661894 |
| Regulated necrosis 1 42 0.4739166707562448 0.8784624909010724 |
| Ripk1 mediated regulated necrosis 0 26 0.0 1.0 |
| Uptake and function of anthrax toxins 0 10 0.0 1.0 |
| Pink1 prkn mediated mitophagy 1 17 1.2175553319919517 0.5734281396877692 |
| O glycosylation of tsr domain containing proteins 0 5 0.0 1.0 |
| O linked glycosylation 1 35 0.5719020002367144 0.8272062968755179 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 0 12 0.0 1.0 |
| Wnt5a dependent internalization of fzd4 0 13 0.0 1.0 |
| Vegfr2 mediated cell proliferation 1 15 1.3917792469100316 0.5284199673110125 |
| Defective c1galt1c1 causes tnps 0 2 0.0 1.0 |
| Defective galnt3 causes hftc 0 1 0.0 1.0 |
| Gpcr ligand binding 1 46 0.4316118935837246 0.9006111912877224 |
| Presynaptic function of kainate receptors 1 13 1.6240778001341385 0.4786734551421467 |
| Signaling by wnt in cancer 2 25 1.6961781206171107 0.3470060894740981 |
| Sumoylation of immune response proteins 0 10 0.0 1.0 |
| Sumoylation of dna methylation proteins 0 16 0.0 1.0 |
| Repression of wnt target genes 0 13 0.0 1.0 |
| Regulation of fzd by ubiquitination 0 9 0.0 1.0 |
| Defective lfng causes scdo3 0 3 0.0 1.0 |
| Acetylcholine regulates insulin secretion 1 8 2.785570566254671 0.3301808657155594 |
| Crmps in sema3a signaling 1 12 1.7719041521858423 0.451869757084416 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0 10 0.0 1.0 |
| Laminin interactions 0 23 0.0 1.0 |
| Initiation of nuclear envelope ne reformation 1 20 1.0249920576088107 0.6330296848923271 |
| Sumoylation 6 155 0.7815518088066786 0.7751417755034482 |
| Activation of nima kinases nek9 nek6 nek7 0 7 0.0 1.0 |
| Nuclear envelope breakdown 2 54 0.7479838709677419 0.7482807316985562 |
| Peptide hormone metabolism 2 43 0.949744295830055 0.6281100642676263 |
| Notch2 activation and transmission of signal to the nucleus 0 16 0.0 1.0 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 0 8 0.0 1.0 |
| Pou5f1 oct4 sox2 nanog repress genes related to differentiation 0 6 0.0 1.0 |
| Fceri mediated ca 2 mobilization 0 20 0.0 1.0 |
| Fceri mediated mapk activation 0 24 0.0 1.0 |
| Role of lat2 ntal lab on calcium mobilization 0 12 0.0 1.0 |
| Signaling by notch1 hd domain mutants in cancer 0 9 0.0 1.0 |
| Eph ephrin signaling 5 80 1.3012846517917511 0.352469032819341 |
| Stimuli sensing channels 0 38 0.0 1.0 |
| Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant 0 4 0.0 1.0 |
| Insulin processing 2 21 2.05411714770798 0.2738488340493723 |
| Syndecan interactions 0 20 0.0 1.0 |
| Non integrin membrane ecm interactions 0 37 0.0 1.0 |
| Ecm proteoglycans 1 37 0.5400178850883076 0.8437295850039954 |
| Scavenging by class b receptors 0 2 0.0 1.0 |
| Chromatin modifying enzymes 8 210 0.7675085875934532 0.8115927304599926 |
| Wnt ligand biogenesis and trafficking 1 9 2.437122736418511 0.3629223192764827 |
| Sumoylation of ubiquitinylation proteins 1 39 0.5114899925871016 0.8586757123257109 |
| Sumoylation of transcription factors 0 18 0.0 1.0 |
| Glycogen storage diseases 1 10 2.1661077576570533 0.3940663935801297 |
| Processing and activation of sumo 1 10 2.1661077576570533 0.3940663935801297 |
| Hats acetylate histones 2 90 0.4403409090909091 0.9387577705701072 |
| Hdms demethylate histones 1 25 0.8110328638497653 0.714470118842069 |
| Acetylcholine neurotransmitter release cycle 1 11 1.9492957746478876 0.4236908718837023 |
| Pkmts methylate histone lysines 1 46 0.4316118935837246 0.9006111912877224 |
| Regulation of innate immune responses to cytosolic dna 0 11 0.0 1.0 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0 5 0.0 1.0 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 0 7 0.0 1.0 |
| Sumoylation of dna damage response and repair proteins 2 76 0.5244115082824761 0.8918488184609167 |
| Sumo is proteolytically processed 0 6 0.0 1.0 |
| Sumo is transferred from e1 to e2 ube2i ubc9 1 7 3.250167672702884 0.295760276625992 |
| Scavenging by class f receptors 0 5 0.0 1.0 |
| Scavenging by class a receptors 0 10 0.0 1.0 |
| Hdacs deacetylate histones 0 40 0.0 1.0 |
| Irf3 mediated induction of type i ifn 0 8 0.0 1.0 |
| Signaling by notch1 pest domain mutants in cancer 2 45 0.9053825956489122 0.6528681906484021 |
| Regulation of plk1 activity at g2 m transition 5 87 1.1893335971899273 0.4211059834024279 |
| Crosslinking of collagen fibrils 0 10 0.0 1.0 |
| Constitutive signaling by aberrant pi3k in cancer 2 32 1.299462365591398 0.4679073600042346 |
| Pi3k akt signaling in cancer 3 58 1.0625895316804408 0.5438179728252587 |
| Anchoring fibril formation 0 8 0.0 1.0 |
| Mucopolysaccharidoses 0 9 0.0 1.0 |
| Notch2 intracellular domain regulates transcription 0 7 0.0 1.0 |
| Visual phototransduction 1 40 0.4983232729711603 0.8656048739892852 |
| The retinoid cycle in cones daylight vision 0 1 0.0 1.0 |
| Egfr transactivation by gastrin 0 7 0.0 1.0 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 0 29 0.0 1.0 |
| Downregulation of smad2 3 smad4 transcriptional activity 0 23 0.0 1.0 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 0 41 0.0 1.0 |
| Downregulation of tgf beta receptor signaling 2 22 1.9512096774193548 0.2922703109028879 |
| Binding and uptake of ligands by scavenger receptors 0 17 0.0 1.0 |
| Dap12 interactions 0 21 0.0 1.0 |
| Scavenging of heme from plasma 0 2 0.0 1.0 |
| Synthesis of prostaglandins pg and thromboxanes tx 0 8 0.0 1.0 |
| Condensation of prophase chromosomes 0 23 0.0 1.0 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 1 29 0.694883587237712 0.7664238447790522 |
| Metabolism of ingested semet sec mesec into h2se 0 4 0.0 1.0 |
| Dap12 signaling 0 19 0.0 1.0 |
| Cytosolic iron sulfur cluster assembly 1 13 1.6240778001341385 0.4786734551421467 |
| Trif mediated programmed cell death 0 4 0.0 1.0 |
| Dna damage telomere stress induced senescence 1 38 0.5253684267768775 0.8513900502920986 |
| Oncogene induced senescence 1 30 0.6708527024214251 0.7778648721483832 |
| Formation of senescence associated heterochromatin foci sahf 0 15 0.0 1.0 |
| Cellular senescence 3 131 0.453125 0.958183920936633 |
| Senescence associated secretory phenotype sasp 3 54 1.14640522875817 0.495315005727891 |
| Oxidative stress induced senescence 1 69 0.2849449639010534 0.9687926182002238 |
| Signaling by leptin 1 8 2.785570566254671 0.3301808657155594 |
| Interaction with cumulus cells and the zona pellucida 0 1 0.0 1.0 |
| Condensation of prometaphase chromosomes 1 11 1.9492957746478876 0.4236908718837023 |
| Activation of the phototransduction cascade 0 2 0.0 1.0 |
| Cohesin loading onto chromatin 0 10 0.0 1.0 |
| Establishment of sister chromatid cohesion 0 11 0.0 1.0 |
| The canonical retinoid cycle in rods twilight vision 0 4 0.0 1.0 |
| Retinoid cycle disease events 0 2 0.0 1.0 |
| Shc related events triggered by igf1r 0 7 0.0 1.0 |
| Activation of gene expression by srebf srebp 2 42 0.9735887096774194 0.6152256119482173 |
| The phototransduction cascade 1 12 1.7719041521858423 0.451869757084416 |
| Trp channels 0 7 0.0 1.0 |
| Defects in cobalamin b12 metabolism 0 10 0.0 1.0 |
| Defects in vitamin and cofactor metabolism 0 18 0.0 1.0 |
| Cd28 dependent pi3k akt signaling 0 15 0.0 1.0 |
| Cd28 co stimulation 2 24 1.7734604105571847 0.3288847005661894 |
| Receptor type tyrosine protein phosphatases 0 11 0.0 1.0 |
| Nuclear receptor transcription pathway 2 29 1.444295101553166 0.4175813594218437 |
| Transport of small molecules 16 377 0.858564844082252 0.7556727810766297 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0 12 0.0 1.0 |
| Olfactory signaling pathway 0 2 0.0 1.0 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 0 27 0.0 1.0 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0 56 0.0 1.0 |
| Transcriptional regulation of white adipocyte differentiation 1 68 0.2892279047418841 0.9671787785083296 |
| Atf6 atf6 alpha activates chaperone genes 0 6 0.0 1.0 |
| Unfolded protein response upr 2 75 0.5316504639858595 0.8874544722584757 |
| Ire1alpha activates chaperones 2 44 0.9270353302611368 0.6406568642020245 |
| Perk regulates gene expression 0 26 0.0 1.0 |
| Atf6 atf6 alpha activates chaperones 0 8 0.0 1.0 |
| Atf4 activates genes in response to endoplasmic reticulum stress 0 22 0.0 1.0 |
| Energy dependent regulation of mtor by lkb1 ampk 1 27 0.7484909456740443 0.7417475603012252 |
| Cd28 dependent vav1 pathway 0 7 0.0 1.0 |
| Glyoxylate metabolism and glycine degradation 0 22 0.0 1.0 |
| Beta oxidation of pristanoyl coa 0 7 0.0 1.0 |
| Sumoylation of transcription cofactors 2 41 0.9986559139784946 0.6020019880837094 |
| Sema3a pak dependent axon repulsion 0 13 0.0 1.0 |
| Trafficking of ampa receptors 0 20 0.0 1.0 |
| G protein beta gamma signalling 2 22 1.9512096774193548 0.2922703109028879 |
| Muscle contraction 1 83 0.2359522991608185 0.9846021320484792 |
| Eph ephrin mediated repulsion of cells 2 43 0.949744295830055 0.6281100642676263 |
| Ephrin signaling 1 17 1.2175553319919517 0.5734281396877692 |
| Prostacyclin signalling through prostacyclin receptor 0 12 0.0 1.0 |
| Signal amplification 2 22 1.9512096774193548 0.2922703109028879 |
| Recruitment of numa to mitotic centrosomes 6 90 1.395760743321719 0.2762651675790059 |
| Rap1 signalling 0 13 0.0 1.0 |
| Adp signalling through p2y purinoceptor 12 1 13 1.6240778001341385 0.4786734551421467 |
| Nitric oxide stimulates guanylate cyclase 0 11 0.0 1.0 |
| Peroxisomal lipid metabolism 1 24 0.8463826436882163 0.6997715576731252 |
| Diseases associated with o glycosylation of proteins 0 17 0.0 1.0 |
| Striated muscle contraction 0 16 0.0 1.0 |
| Association of tric cct with target proteins during biosynthesis 0 36 0.0 1.0 |
| Folding of actin by cct tric 0 10 0.0 1.0 |
| Beta oxidation of very long chain fatty acids 0 9 0.0 1.0 |
| G beta gamma signalling through pi3kgamma 1 15 1.3917792469100316 0.5284199673110125 |
| Recruitment of mitotic centrosome proteins and complexes 4 82 0.9986504723346828 0.5732190529411857 |
| Chemokine receptors bind chemokines 0 3 0.0 1.0 |
| Mitochondrial trna aminoacylation 1 23 0.8849460398756174 0.6843179386047307 |
| Diseases associated with glycosaminoglycan metabolism 1 26 0.7785110663983903 0.7284504433708964 |
| Grb2 sos provides linkage to mapk signaling for integrins 1 9 2.437122736418511 0.3629223192764827 |
| Integrin signaling 1 18 1.1458160729080364 0.5942978505128852 |
| Amino acid transport across the plasma membrane 1 17 1.2175553319919517 0.5734281396877692 |
| Apoptotic cleavage of cell adhesion proteins 1 9 2.437122736418511 0.3629223192764827 |
| Notch hlh transcription pathway 0 21 0.0 1.0 |
| Hsf1 dependent transactivation 1 30 0.6708527024214251 0.7778648721483832 |
| Attenuation phase 0 22 0.0 1.0 |
| Defective b4galt7 causes eds progeroid type 0 13 0.0 1.0 |
| Cellular response to heat stress 6 93 1.347210541070928 0.3018849324243823 |
| Regulation of hsf1 mediated heat shock response 5 76 1.3751678427563352 0.313402137595613 |
| Regulation by c flip 0 10 0.0 1.0 |
| Defects in biotin btn metabolism 0 8 0.0 1.0 |
| Glycogen synthesis 1 11 1.9492957746478876 0.4236908718837023 |
| Signaling by tgf beta receptor complex in cancer 1 8 2.785570566254671 0.3301808657155594 |
| Loss of function of smad2 3 in cancer 0 7 0.0 1.0 |
| Nuclear pore complex npc disassembly 1 36 0.5555044553032481 0.8356750759447882 |
| Detoxification of reactive oxygen species 0 24 0.0 1.0 |
| Hsf1 activation 1 25 0.8110328638497653 0.714470118842069 |
| Hyaluronan uptake and degradation 1 8 2.785570566254671 0.3301808657155594 |
| Defective chst3 causes sedcjd 0 4 0.0 1.0 |
| Defective chsy1 causes tpbs 0 4 0.0 1.0 |
| Trna aminoacylation 3 43 1.4633333333333334 0.3510943394250187 |
| Cytosolic trna aminoacylation 2 24 1.7734604105571847 0.3288847005661894 |
| Dopamine clearance from the synaptic cleft 0 2 0.0 1.0 |
| Diseases of glycosylation 2 76 0.5244115082824761 0.8918488184609167 |
| Diseases associated with n glycosylation of proteins 0 18 0.0 1.0 |
| Negative regulation of tcf dependent signaling by wnt ligand antagonists 0 5 0.0 1.0 |
| Deactivation of the beta catenin transactivating complex 1 36 0.5555044553032481 0.8356750759447882 |
| Dscam interactions 0 9 0.0 1.0 |
| Defective chst14 causes eds musculocontractural type 0 4 0.0 1.0 |
| Peptide ligand binding receptors 1 17 1.2175553319919517 0.5734281396877692 |
| Nephrin family interactions 1 17 1.2175553319919517 0.5734281396877692 |
| Class b 2 secretin family receptors 0 25 0.0 1.0 |
| Class a 1 rhodopsin like receptors 1 21 0.9736418511066398 0.6509887274409705 |
| Signaling by gpcr 9 204 0.8969325153374234 0.6709400563403464 |
| P130cas linkage to mapk signaling for integrins 1 9 2.437122736418511 0.3629223192764827 |
| Defective b4galt1 causes b4galt1 cdg cdg 2d 0 1 0.0 1.0 |
| Defective ext2 causes exostoses 2 0 11 0.0 1.0 |
| Defective chst6 causes mcdc1 0 1 0.0 1.0 |
| Semaphorin interactions 3 48 1.30006734006734 0.4181534738954689 |
| Ion channel transport 2 82 0.4847782258064516 0.9150357038132068 |
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