| term overlap setsize score pval |
| Mrna splicing 40 140 -2.6997553069744025 0.0069390491512053 |
| Defects in biotin btn metabolism 4 7 -2.5284020315471607 0.0114583059931416 |
| Heme degradation 1 4 2.3137138343535173 0.0206834245243654 |
| Biotin transport and metabolism 5 9 -2.275926460504289 0.0228504114733589 |
| Thrombin signalling through proteinase activated receptors pars 2 6 -2.2507336013098413 0.0244024152258548 |
| Glyoxylate metabolism and glycine degradation 9 11 -2.161358444595088 0.0306676614959191 |
| Gaba b receptor activation 4 6 -2.157421981978674 0.0309727999897475 |
| Adp signalling through p2y purinoceptor 12 4 6 -2.157421981978674 0.0309727999897475 |
| G alpha z signalling events 4 6 -2.157421981978674 0.0309727999897475 |
| Scavenging by class b receptors 0 1 2.1378490834147867 0.032528993838633 |
| Constitutive signaling by aberrant pi3k in cancer 1 6 -2.136005122429925 0.0326789962960945 |
| Glucagon signaling in metabolic regulation 2 6 -2.128604116661338 0.033287027638909 |
| Vasopressin regulates renal water homeostasis via aquaporins 2 6 -2.128604116661338 0.033287027638909 |
| Met receptor activation 1 1 -2.1220389544596814 0.0338344669685803 |
| Hydrolysis of lpc 0 1 2.10722151500874 0.0350983828192701 |
| Signaling by tgf beta receptor complex in cancer 1 1 -2.0958589061645183 0.0360947090207766 |
| Lysine catabolism 5 6 -2.0939623239168728 0.0362633366052294 |
| Synthesis of lipoxins lx 0 1 2.0811543499885383 0.0374197804367784 |
| Sensory perception of taste 1 1 -2.074273350842035 0.0380539313211512 |
| Olfactory signaling pathway 1 1 -2.074273350842035 0.0380539313211512 |
| Activation of the phototransduction cascade 1 1 -2.074273350842035 0.0380539313211512 |
| Pyrimidine catabolism 1 1 -2.035672371925008 0.0417832651602938 |
| Runx1 regulates estrogen receptor mediated transcription 0 1 2.030469423419916 0.0423088461554965 |
| Triglyceride biosynthesis 0 1 2.030469423419916 0.0423088461554965 |
| Defects in vitamin and cofactor metabolism 4 11 -2.023368653594719 0.0430351535013118 |
| Gaba receptor activation 4 7 -2.020731225210627 0.0433075956214303 |
| Regulation of gene expression by hypoxia inducible factor 0 1 2.0073961421642528 0.0447074992782416 |
| Thromboxane signalling through tp receptor 2 5 -1.9890427765577297 0.046696481611504 |
| Acetylcholine regulates insulin secretion 1 1 -1.9877133356535448 0.0468434031919247 |
| Urea cycle 0 1 1.9873827527506296 0.0468799974928373 |
| Phosphate bond hydrolysis by nudt proteins 2 4 -1.9856175192109664 0.047075809668521 |
| G beta gamma signalling through cdc42 2 5 -1.9808482145715176 0.0476082979658731 |
| Regulation of pyruvate dehydrogenase pdh complex 4 7 -1.9711045550952049 0.048711917830913 |
| Small interfering rna sirna biogenesis 1 4 -1.965623721582808 0.0493420918637159 |
| G beta gamma signalling through pi3kgamma 3 5 -1.9505719059943156 0.0511079919030543 |
| Ldl remodeling 1 1 -1.9458633780661865 0.0516711530610118 |
| Vldl assembly 1 1 -1.9458633780661865 0.0516711530610118 |
| Tnfr1 mediated ceramide production 1 1 -1.944312037782618 0.0518578338908017 |
| Mecp2 regulates neuronal receptors and channels 3 7 -1.9338864682304584 0.0531270882259371 |
| Dermatan sulfate biosynthesis 0 1 1.9334292409736384 0.0531833419851255 |
| Defective chst14 causes eds musculocontractural type 0 1 1.9334292409736384 0.0531833419851255 |
| G protein beta gamma signalling 3 7 -1.9235455530667416 0.054411571368413 |
| G alpha s signalling events 4 8 -1.9157738360248688 0.0553938894184458 |
| Signaling by fgfr2 iiia tm 2 8 -1.905871676080704 0.0566668566600347 |
| Fgfr2 mutant receptor activation 2 8 -1.905871676080704 0.0566668566600347 |
| Passive transport by aquaporins 0 1 1.9056444230587253 0.0566963544638099 |
| Collagen degradation 0 1 1.8963776422095813 0.0579101261171022 |
| Adrenaline noradrenaline inhibits insulin secretion 3 5 -1.895457749202519 0.0580317841562147 |
| Propionyl coa catabolism 1 3 -1.8920198929903 0.0584883303662309 |
| Arachidonic acid metabolism 2 7 1.8871720744752605 0.0591371850382875 |
| Abacavir transmembrane transport 0 1 1.8871083952461245 0.0591457477587522 |
| Slbp dependent processing of replication dependent histone pre mrnas 2 3 -1.8815059270417724 0.0599031297777203 |
| Androgen biosynthesis 0 1 1.8762912566863992 0.0606152969736157 |
| Adp signalling through p2y purinoceptor 1 2 4 -1.8731544576694343 0.0610470591505336 |
| Sema4d mediated inhibition of cell attachment and migration 2 3 -1.869203568145347 0.0615944980484808 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 1 4 1.854357147258534 0.0636880812848308 |
| Signal amplification 4 9 -1.8508967406114167 0.0641844097587749 |
| Sulfide oxidation to sulfate 0 1 1.837633907362909 0.0661163688961419 |
| Metabolism of lipids 51 197 1.8289035916724117 0.0674140520974244 |
| Regulation of fzd by ubiquitination 1 1 -1.824602388177423 0.0680610527808647 |
| Metabolism of fat soluble vitamins 1 4 -1.8183780344457667 0.0690063732508994 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 1 1 -1.8168133693284256 0.0692456950083788 |
| Dna methylation 2 4 -1.8111544813064009 0.0701169420376135 |
| Transport of nucleotide sugars 0 1 1.8097791112152224 0.0703300485178073 |
| Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0 1 1.8004906347794998 0.0717832010410117 |
| Sphingolipid de novo biosynthesis 5 11 1.790930129782794 0.0733045079600667 |
| Ca2 pathway 2 6 -1.7899153249805928 0.0734675248036791 |
| Chrebp activates metabolic gene expression 2 5 -1.7852983542008392 0.0742129356847514 |
| Pi3k akt activation 1 1 -1.784081920150984 0.0744103546676364 |
| Rho gtpases activate rhotekin and rhophilins 1 1 -1.784081920150984 0.0744103546676364 |
| Met activates rap1 and rac1 2 5 -1.7755014902276844 0.0758151197109946 |
| Class b 2 secretin family receptors 2 4 -1.7734024493120206 0.0761620434411161 |
| Detoxification of reactive oxygen species 5 9 -1.7733320974608953 0.0761736933924299 |
| Nucleotide catabolism 3 10 -1.771320436547374 0.076507430905502 |
| Metabolism of porphyrins 1 8 1.767737045114641 0.0771048738350563 |
| Surfactant metabolism 0 1 1.7602229325932808 0.0783700151615578 |
| Met receptor recycling 2 5 -1.748348233043087 0.0804037459820488 |
| Activation of kainate receptors upon glutamate binding 2 5 -1.7389381161379058 0.0820456487473304 |
| Purine catabolism 2 8 -1.7383704028174565 0.0821455683541954 |
| Met promotes cell motility 2 6 -1.735404893258737 0.0826691139842732 |
| Adora2b mediated anti inflammatory cytokines production 4 10 -1.7293039290716894 0.0837547138110654 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 2 7 -1.7265327111979671 0.0842516196704323 |
| Activation of puma and translocation to mitochondria 1 1 -1.7201069512651326 0.0854130024159474 |
| Runx3 regulates cdkn1a transcription 1 1 -1.7201069512651326 0.0854130024159474 |
| Activation of noxa and translocation to mitochondria 1 1 -1.7201069512651326 0.0854130024159474 |
| Tp53 regulates transcription of genes involved in cytochrome c release 1 1 -1.7201069512651326 0.0854130024159474 |
| Glutamate and glutamine metabolism 7 8 -1.7134957140291995 0.0866213811824314 |
| Regulation of pten mrna translation 0 1 1.710631944407069 0.0871490781085024 |
| Competing endogenous rnas cernas regulate pten translation 0 1 1.710631944407069 0.0871490781085024 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 1 4 -1.705721780658494 0.0880598924201963 |
| Prolonged erk activation events 2 5 -1.7051607014108678 0.0881644571094697 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 2 4 -1.6973614803723678 0.0896283403528293 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 2 3 -1.6952262549384494 0.090032508125653 |
| O linked glycosylation of mucins 1 5 1.692794048766793 0.09049467587774 |
| O linked glycosylation 1 5 1.692794048766793 0.09049467587774 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 1 1 -1.69199672907716 0.0906465972858323 |
| Pink1 prkn mediated mitophagy 2 10 1.6883627036709057 0.0913416253135432 |
| Nicotinate metabolism 1 4 1.687919354566679 0.0914267107682338 |
| Regulation of foxo transcriptional activity by acetylation 0 1 1.6873784376449927 0.091530607243613 |
| Processing of capped intron containing pre mrna 69 180 -1.6760615662966805 0.0937261339441208 |
| Norepinephrine neurotransmitter release cycle 0 1 1.668773635235947 0.095162249602104 |
| Acetylcholine neurotransmitter release cycle 0 1 1.668773635235947 0.095162249602104 |
| Receptor type tyrosine protein phosphatases 0 1 1.668773635235947 0.095162249602104 |
| Serotonin neurotransmitter release cycle 0 1 1.668773635235947 0.095162249602104 |
| Hs gag biosynthesis 0 1 1.6579203995694392 0.0973335340890391 |
| Regulated proteolysis of p75ntr 1 1 -1.6560628925803036 0.0977090830231701 |
| Signaling by retinoic acid 4 9 -1.6526276051727675 0.0984066763255684 |
| Gaba synthesis release reuptake and degradation 2 3 -1.648738254532888 0.0992012694250354 |
| Synthesis of pips at the er membrane 1 3 -1.6446340669844193 0.1000452970941365 |
| The nlrp3 inflammasome 0 4 1.6399689094570231 0.101011631526819 |
| Inflammasomes 0 4 1.6399689094570231 0.101011631526819 |
| Purinergic signaling in leishmaniasis infection 0 4 1.6399689094570231 0.101011631526819 |
| Negative regulation of met activity 3 7 -1.6391621410970052 0.1011794961308321 |
| G2 phase 0 1 1.637764274538466 0.1014708767579251 |
| Diseases associated with n glycosylation of proteins 1 7 1.6358392366262118 0.1018732378217759 |
| Glucagon type ligand receptors 2 3 -1.6335087894547893 0.1023620336673105 |
| Presynaptic function of kainate receptors 2 3 -1.6335087894547893 0.1023620336673105 |
| Prostacyclin signalling through prostacyclin receptor 2 3 -1.6335087894547893 0.1023620336673105 |
| G protein activation 2 3 -1.6335087894547893 0.1023620336673105 |
| Potassium channels 2 3 -1.6335087894547893 0.1023620336673105 |
| Inwardly rectifying k channels 2 3 -1.6335087894547893 0.1023620336673105 |
| Glycogen breakdown glycogenolysis 5 6 1.6327220113261778 0.1025274758894765 |
| Bmal1 clock npas2 activates circadian gene expression 1 3 1.6134214512128822 0.1066529758233749 |
| Rrna modification in the mitochondrion 0 1 1.5959057321847383 0.1105098415535073 |
| Aquaporin mediated transport 2 7 -1.588989275403369 0.1120628139896542 |
| Synthesis of udp n acetyl glucosamine 2 5 -1.581204808786418 0.1138312162102184 |
| Synthesis of pg 1 4 1.5754365806819968 0.1151557063067416 |
| Signaling by fgfr2 in disease 2 10 -1.574160823972837 0.1154502737688458 |
| Attachment and entry 1 1 -1.5700989286189309 0.1163920978103218 |
| Lgi adam interactions 1 1 -1.5497800991380044 0.1211943051650785 |
| Met activates ras signaling 1 4 -1.5479450564546646 0.121635525431937 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 3 5 1.5388136154875407 0.1238498049385525 |
| Er quality control compartment erqc 1 3 1.5380845572211683 0.1240279413364595 |
| Trafficking of myristoylated proteins to the cilium 0 3 1.5279143371300334 0.1265338080404916 |
| Mitochondrial iron sulfur cluster biogenesis 2 4 -1.5258818618873922 0.127039288627403 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 1 1.5230839866184014 0.1277376946037263 |
| Erythropoietin activates stat5 0 1 1.5230839866184014 0.1277376946037263 |
| Dectin 2 family 0 1 1.5230839866184014 0.1277376946037263 |
| Cd22 mediated bcr regulation 0 1 1.5230839866184014 0.1277376946037263 |
| 2 ltr circle formation 1 4 -1.521944107627791 0.1280230860101743 |
| Met activates ptpn11 1 3 -1.519335354451432 0.1286781049163792 |
| Acyl chain remodelling of pi 0 1 1.5168905814256286 0.129294311978078 |
| Effects of pip2 hydrolysis 2 3 1.5114207326354212 0.1306812903593885 |
| Transport of small molecules 31 159 1.499095372867581 0.1338488918261238 |
| Extra nuclear estrogen signaling 4 12 -1.4915471872515549 0.1358178920923165 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 2 3 1.489141649267719 0.1364500723369479 |
| Endosomal vacuolar pathway 1 4 1.4871341639078035 0.1369793799647574 |
| Mrna editing 1 1 -1.4794744798774155 0.1390135470884272 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 2 4 -1.4775796233193366 0.1395203317198978 |
| Keratan sulfate keratin metabolism 3 6 1.4770299578610937 0.1396676070421514 |
| Notch hlh transcription pathway 2 5 -1.4735700245121128 0.1405973970910263 |
| Folding of actin by cct tric 7 8 -1.458974187531387 0.1445722123057402 |
| Binding and uptake of ligands by scavenger receptors 0 6 1.4534152353166898 0.1461084989139569 |
| Integration of provirus 1 5 -1.4507277644017278 0.1468556810738128 |
| Inlb mediated entry of listeria monocytogenes into host cell 1 5 -1.4483780107181452 0.1475113610966791 |
| Glycogen storage diseases 1 3 1.441148432242271 0.1495427532841791 |
| Downregulation of erbb4 signaling 0 1 1.4395595314595362 0.1499920559226222 |
| Rho gtpase cycle 57 154 1.435055279165562 0.1512713458304535 |
| Synthesis of prostaglandins pg and thromboxanes tx 1 4 1.432489333042258 0.1520038287134379 |
| Signaling by bmp 1 1 -1.4279709351727117 0.1533002244399952 |
| Gastrin creb signalling pathway via pkc and mapk 1 4 1.423054345727441 0.1547204016090622 |
| Creatine metabolism 1 3 -1.4221105199047457 0.1549941693087788 |
| Signaling by notch1 pest domain mutants in cancer 3 7 -1.417444149381539 0.1563531124676456 |
| Glycogen metabolism 6 9 1.4144946983641895 0.157216702920182 |
| Prc2 methylates histones and dna 1 5 -1.412581109565501 0.157778926616515 |
| Purine ribonucleoside monophosphate biosynthesis 5 10 -1.394029818181722 0.163308600471423 |
| Mrna decay by 5 to 3 exoribonuclease 6 9 -1.3930495738897513 0.1636048002223609 |
| Reduction of cytosolic ca levels 2 4 -1.3906321348332449 0.1643370066003289 |
| Platelet calcium homeostasis 2 4 -1.3906321348332449 0.1643370066003289 |
| Rsk activation 1 3 1.3889140170671324 0.1648588976292206 |
| Citric acid cycle tca cycle 15 18 -1.3865084861847994 0.1655916908124015 |
| Activation of bad and translocation to mitochondria 6 8 -1.38112993749625 0.1672390121253033 |
| Adenylate cyclase inhibitory pathway 3 3 -1.378298362832366 0.1681111884715309 |
| Synthesis of pa 2 10 1.377368958739168 0.1683982049131713 |
| Activation of bh3 only proteins 8 11 -1.375947187379127 0.1688379845638388 |
| Ethanol oxidation 3 3 -1.3711820057616553 0.1703182261184896 |
| Regulation of tp53 activity through methylation 3 6 -1.369974827282193 0.1706947596796943 |
| Negative regulators of ddx58 ifih1 signaling 3 8 -1.3688249973130402 0.1710539850604986 |
| Sumoylation of transcription cofactors 11 14 -1.368191757522954 0.1712520609501087 |
| Platelet homeostasis 3 12 -1.3663924269148355 0.171815824498001 |
| Synthesis of pips at the late endosome membrane 2 4 -1.3579711601535265 0.1744728355323626 |
| Regulation of localization of foxo transcription factors 4 6 -1.3507928500132809 0.1767617991117624 |
| Visual phototransduction 2 8 -1.3494753407828393 0.1771843356632747 |
| Activation of rac1 downstream of nmdars 1 3 1.348674141847786 0.1774416546773598 |
| Synthesis of pc 2 6 1.3338717706575265 0.1822458845521846 |
| Metabolism of cofactors 3 5 1.3316047084668488 0.1829901169056642 |
| Beta oxidation of very long chain fatty acids 2 4 1.3211493059914126 0.1864515855100246 |
| Activated tak1 mediates p38 mapk activation 3 4 1.3183298415766682 0.1873932554620352 |
| Beta oxidation of pristanoyl coa 2 4 1.317014662795731 0.1878337096803453 |
| Tgf beta receptor signaling activates smads 7 9 -1.310846295886134 0.1899096978511039 |
| Heme biosynthesis 2 4 -1.309989502007406 0.1901993870177847 |
| Insulin receptor recycling 2 9 1.3096064338461082 0.1903290107950339 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 2 3 1.3057989546954585 0.1916209356448357 |
| Peptide ligand binding receptors 2 7 1.301011680564382 0.19325445659648 |
| Class a 1 rhodopsin like receptors 2 7 1.301011680564382 0.19325445659648 |
| Biosynthesis of specialized proresolving mediators spms 0 2 1.299441779705575 0.1937923614500847 |
| Synthesis of leukotrienes lt and eoxins ex 0 2 1.299441779705575 0.1937923614500847 |
| Formation of tubulin folding intermediates by cct tric 10 11 -1.2912193043223192 0.1966276430320106 |
| Iron uptake and transport 8 17 1.283304120956921 0.1993855494949397 |
| Regulation of commissural axon pathfinding by slit and robo 0 1 1.276494285204052 0.201780845692987 |
| Keratan sulfate degradation 2 4 1.2760373802062406 0.2019423056070945 |
| Irf3 mediated induction of type i ifn 3 5 1.2753224032281636 0.2021951513045869 |
| Sting mediated induction of host immune responses 3 5 1.2753224032281636 0.2021951513045869 |
| Hdl clearance 0 2 1.2692289322633352 0.2043594248958316 |
| Dopamine neurotransmitter release cycle 0 3 1.268799904835265 0.2045124390926229 |
| Amyloid fiber formation 3 6 -1.2686218976695856 0.2045759504520674 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 4 8 -1.267432292416131 0.2050007592317881 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0 1 1.2673157132952413 0.2050424241884592 |
| Mitophagy 2 14 1.264118807447197 0.2061873870849579 |
| Metabolic disorders of biological oxidation enzymes 4 5 -1.2625900946899784 0.2067365294890351 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 1 3 1.2623991278694244 0.2068052028953197 |
| Mrna capping 2 12 -1.2589430477318675 0.2080509035960798 |
| Trna processing in the mitochondrion 4 4 -1.2581475713788657 0.2083383917443644 |
| Ptk6 expression 0 1 1.2581440449714356 0.2083396668421082 |
| Complement cascade 1 1 -1.2477124955197032 0.2121363636247126 |
| Unwinding of dna 5 10 1.2474763869812668 0.2122228731313877 |
| Cholesterol biosynthesis 6 18 1.243032340990409 0.2138559160662827 |
| Listeria monocytogenes entry into host cells 1 7 -1.229563301539899 0.2188606796110357 |
| Calcineurin activates nfat 1 2 -1.228984074687301 0.2190777769795822 |
| Negative regulation of flt3 1 1 -1.2260827414635744 0.2201675397762466 |
| Plasma lipoprotein assembly 1 3 -1.224411405791361 0.2207970687628404 |
| Signaling by interleukins 27 107 1.223743367533214 0.2210490542201924 |
| E2f enabled inhibition of pre replication complex formation 1 5 1.2225459505277043 0.2215012382619337 |
| Inhibition of dna recombination at telomere 4 10 -1.1952104974392035 0.2320047981704918 |
| Protein methylation 3 7 -1.1941936539750304 0.2324022249067936 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0 1 1.1941552305914254 0.2324172519066034 |
| Ticam1 traf6 dependent induction of tak1 complex 0 1 1.1911182544993573 0.2336071645834803 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 0 1 1.1911182544993573 0.2336071645834803 |
| Irak2 mediated activation of tak1 complex 0 1 1.1911182544993573 0.2336071645834803 |
| Alpha protein kinase 1 signaling pathway 0 1 1.1911182544993573 0.2336071645834803 |
| Triglyceride catabolism 4 5 -1.187836460703399 0.2348978466383071 |
| Enos activation 1 4 -1.184077557994882 0.2363823628779391 |
| Intrinsic pathway of fibrin clot formation 0 2 1.180304125177688 0.2378792780506922 |
| Formation of fibrin clot clotting cascade 0 2 1.180304125177688 0.2378792780506922 |
| Pyroptosis 2 3 -1.1785951324901685 0.2385594307874119 |
| Transferrin endocytosis and recycling 4 10 1.1743709878666428 0.2402464606783936 |
| Polo like kinase mediated events 2 4 -1.1685935227715398 0.242567439144985 |
| Platelet aggregation plug formation 2 4 -1.1685832068905808 0.2425715973929056 |
| Integrin signaling 2 4 -1.1685832068905808 0.2425715973929056 |
| Regulation of ifng signaling 3 4 -1.1666366221974849 0.2433571472480569 |
| Regulation of innate immune responses to cytosolic dna 0 2 1.1635640709967126 0.2446007189023413 |
| Maturation of sars cov 1 spike protein 3 4 -1.1582295382972057 0.2467703771238385 |
| Met activates pi3k akt signaling 1 2 -1.1576991964399057 0.2469868120057241 |
| Pentose phosphate pathway 5 7 -1.157185187195215 0.2471967083244548 |
| Negative regulation of the pi3k akt network 1 11 -1.1549046155568856 0.2481294891152774 |
| Miscellaneous transport and binding events 3 7 1.1543175083810735 0.2483700210066932 |
| Signaling by egfr in cancer 3 4 1.154198565549525 0.2484187705490637 |
| Constitutive signaling by ligand responsive egfr cancer variants 3 4 1.154198565549525 0.2484187705490637 |
| Constitutive signaling by egfrviii 3 4 1.154198565549525 0.2484187705490637 |
| Nucleotide biosynthesis 8 12 -1.1512181651217297 0.2496424939078751 |
| Diseases of mismatch repair mmr 2 3 1.1507814200698654 0.2498221704072347 |
| Netrin mediated repulsion signals 1 1 -1.1491503893805548 0.2504939735200935 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 1 1 -1.1491503893805548 0.2504939735200935 |
| Nostrin mediated enos trafficking 0 1 1.1471982027320151 0.2512997142150825 |
| Choline catabolism 1 1 -1.146084673268967 0.2517601186530391 |
| Fceri mediated ca 2 mobilization 1 5 1.1418550477658889 0.2535142763766322 |
| Heparan sulfate heparin hs gag metabolism 1 4 1.137756923319848 0.2552219968611449 |
| Neurotransmitter release cycle 3 8 -1.131637722569493 0.2577867739765473 |
| Miro gtpase cycle 3 5 -1.1286427294884298 0.259048577678886 |
| Sumoylation of transcription factors 3 6 -1.1265451997805769 0.2599348198324467 |
| Erythrocytes take up carbon dioxide and release oxygen 1 1 -1.1139553846134385 0.2652983273013296 |
| Cdc6 association with the orc origin complex 0 3 1.113746310447315 0.2653880358299003 |
| Carboxyterminal post translational modifications of tubulin 1 4 -1.1128459551585337 0.2657745946204397 |
| Hemostasis 37 122 -1.1102557045803334 0.2668888548448882 |
| Dap12 interactions 3 5 1.1069875161904454 0.2682993257642083 |
| Negative feedback regulation of mapk pathway 1 3 -1.1068262767889556 0.268369045081968 |
| Regulation of insulin secretion 4 14 -1.1037261187553324 0.269711962047743 |
| Class i mhc mediated antigen processing presentation 18 124 1.101206561134657 0.2708067667877558 |
| Role of phospholipids in phagocytosis 1 3 1.1001403507415253 0.271270975184001 |
| Ikk complex recruitment mediated by rip1 2 3 1.0969914929252529 0.2726451109223653 |
| Ticam1 rip1 mediated ikk complex recruitment 2 3 1.0969914929252529 0.2726451109223653 |
| Processing of capped intronless pre mrna 6 16 -1.0968166290894588 0.2727215593968664 |
| Toxicity of botulinum toxin type d botd 0 1 1.0915122927690066 0.275047525787254 |
| Neurotoxicity of clostridium toxins 0 1 1.0915122927690066 0.275047525787254 |
| Mrna splicing minor pathway 11 31 -1.0897951505185604 0.2758033906491448 |
| Fgfr2 alternative splicing 2 14 -1.0886423250305148 0.2763116445270743 |
| Trna modification in the mitochondrion 3 7 -1.0853982807070808 0.2777452935479894 |
| Nod1 2 signaling pathway 4 6 1.078967128940165 0.2806023814359013 |
| Methionine salvage pathway 0 4 1.0763074664923962 0.2817897705056198 |
| Met activates ptk2 signaling 1 2 -1.0742917083982462 0.2826919601091493 |
| Met interacts with tns proteins 1 2 -1.0742917083982462 0.2826919601091493 |
| Beta oxidation of butanoyl coa to acetyl coa 0 4 1.067774719851759 0.2856221441237467 |
| Stimuli sensing channels 0 8 1.0627426167166936 0.2878986887745736 |
| Pi5p regulates tp53 acetylation 2 2 -1.0574841652179294 0.2902906776389566 |
| Ion transport by p type atpases 2 12 -1.0509966558335768 0.2932601257554248 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 1 3 1.0496590981247111 0.2938748753091325 |
| Aryl hydrocarbon receptor signalling 2 3 -1.042913461839449 0.2969883742546901 |
| Ros and rns production in phagocytes 1 8 1.0389278144442573 0.2988383093821571 |
| Creb1 phosphorylation through the activation of adenylate cyclase 1 3 -1.0370680028945862 0.2997041659540786 |
| Pka activation in glucagon signalling 1 3 -1.0370680028945862 0.2997041659540786 |
| Pka mediated phosphorylation of creb 1 3 -1.0370680028945862 0.2997041659540786 |
| Bbsome mediated cargo targeting to cilium 5 7 -1.0367853429757743 0.2998359078480632 |
| G alpha 12 13 signalling events 3 12 -1.0350728434575294 0.3006348938307384 |
| Cellular hexose transport 0 1 1.034795689250028 0.3007643365209826 |
| Regulation of ifna signaling 3 3 -1.0346602629098838 0.3008275998304925 |
| Regulation of tp53 activity through acetylation 4 12 -1.031626627647184 0.3022470614251018 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 7 10 1.0299731482189782 0.3030226107161793 |
| Ptk6 regulates cell cycle 1 2 1.0280506593636909 0.3039259984196349 |
| Nephrin family interactions 4 7 1.0227593848241945 0.3064216257392447 |
| Pi3k akt signaling in cancer 1 11 -1.016492885293923 0.3093947338117084 |
| Diseases associated with glycosaminoglycan metabolism 2 4 1.0127616818881848 0.3111740074500106 |
| Post chaperonin tubulin folding pathway 3 9 -1.0071281758770616 0.3138731827441898 |
| Rho gtpases activate ktn1 2 8 -1.0053062068084513 0.3147494273059514 |
| Sodium proton exchangers 0 1 1.0007335602024592 0.3169556378825722 |
| Sphingolipid metabolism 11 26 1.0006558964928054 0.3169931964596155 |
| Sodium calcium exchangers 1 1 -1.0002658098618018 0.317181888549638 |
| Pyrimidine salvage 1 3 1.000177528472601 0.3172246021026739 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 1 3 -0.9983119003374912 0.3181281387986301 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 2 4 0.9932538428147284 0.3205862651047053 |
| Base excision repair ap site formation 0 4 0.990041461806904 0.3221538537065105 |
| Rna polymerase ii transcribes snrna genes 4 30 -0.9895654816445272 0.3223865488892561 |
| Erbb2 regulates cell motility 1 2 -0.98687789352675 0.323702502746398 |
| Mapk targets nuclear events mediated by map kinases 4 9 0.9847640580193106 0.3247399791375485 |
| Erk mapk targets 4 9 0.9847640580193106 0.3247399791375485 |
| Flt3 signaling 3 5 -0.9845609983609194 0.3248397552020261 |
| Apobec3g mediated resistance to hiv 1 infection 1 2 -0.9836176697860072 0.3253035338539605 |
| Ikba variant leads to eda id 0 1 0.9801082968684756 0.3270326641022532 |
| Sumoylation of immune response proteins 0 1 0.9801082968684756 0.3270326641022532 |
| Transcription of e2f targets under negative control by dream complex 2 3 -0.9777008415000276 0.3282223054645272 |
| Transport and synthesis of paps 1 3 0.9773069570900804 0.3284172098682396 |
| Prevention of phagosomal lysosomal fusion 1 4 0.9752999575362832 0.3294114915470403 |
| Ketone body metabolism 2 5 -0.9731235225443976 0.3304919145063558 |
| Synthesis of ketone bodies 2 5 -0.9731235225443976 0.3304919145063558 |
| Interleukin 23 signaling 1 2 -0.9720558750768454 0.3310227521200071 |
| Transport of connexons to the plasma membrane 1 3 -0.971277456506469 0.3314101316766606 |
| Gap junction assembly 1 3 -0.971277456506469 0.3314101316766606 |
| Processing of intronless pre mrnas 3 14 -0.9701598502627892 0.3319668200928345 |
| Peroxisomal lipid metabolism 6 12 0.9685425383521462 0.3327734851275865 |
| Irs activation 1 1 -0.9628070265010578 0.335644373901552 |
| Ras signaling downstream of nf1 loss of function variants 0 1 0.9581067002530508 0.3380089571818021 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 12 15 -0.9543520142472002 0.3399054873070306 |
| Antimicrobial peptides 2 2 -0.9530889109061956 0.3405450241438137 |
| Transport of inorganic cations anions and amino acids oligopeptides 5 11 0.9518572821717208 0.3411693665142437 |
| Glucuronidation 0 3 0.9509852256032908 0.3416118759274633 |
| Defective factor ix causes hemophilia b 0 1 0.9507960445717988 0.3417079208996902 |
| Gamma carboxylation transport and amino terminal cleavage of proteins 0 1 0.9507960445717988 0.3417079208996902 |
| Defects of contact activation system cas and kallikrein kinin system kks 0 1 0.9507960445717988 0.3417079208996902 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 0 7 0.9422413852840426 0.3460690699728048 |
| Resolution of d loop structures 0 7 0.9422413852840426 0.3460690699728048 |
| Nrif signals cell death from the nucleus 1 2 -0.9401437392422274 0.34714383567926 |
| Glycosaminoglycan metabolism 7 14 0.9379592475366828 0.348265353475031 |
| Tnfr1 induced nfkappab signaling pathway 3 6 -0.9274818696627912 0.353676400867033 |
| Diseases associated with o glycosylation of proteins 0 2 0.9261714342791983 0.3543568952247853 |
| Attachment of gpi anchor to upar 2 5 0.925197167151167 0.3548633567983468 |
| Fceri mediated mapk activation 6 7 0.9217799996636424 0.3566433418775487 |
| Assembly of active lpl and lipc lipase complexes 0 1 0.917324333151868 0.3589727101096731 |
| Abortive elongation of hiv 1 transcript in the absence of tat 2 12 -0.9159198539240232 0.3597089326663141 |
| Mitotic metaphase and anaphase 34 136 0.9151839934986996 0.3600950461951742 |
| Mucopolysaccharidoses 2 4 0.9123136152415244 0.3616036490638112 |
| Bicarbonate transporters 0 1 0.9115305471944876 0.3620158979665104 |
| Downregulation of tgf beta receptor signaling 5 7 -0.9114905838073456 0.3620369447260114 |
| Sumoylation of dna methylation proteins 2 4 -0.9109160202641822 0.3623396239607088 |
| Ra biosynthesis pathway 0 3 0.9080204178461326 0.3638674342773904 |
| Caspase activation via dependence receptors in the absence of ligand 1 1 -0.9063731440199148 0.3647383825630848 |
| Activation of caspases through apoptosome mediated cleavage 1 1 -0.9063731440199148 0.3647383825630848 |
| Phenylalanine and tyrosine metabolism 3 5 -0.9059027253063908 0.3649873417177032 |
| Transport of bile salts and organic acids metal ions and amine compounds 1 3 0.9054643968113448 0.3652194133090591 |
| Synthesis of very long chain fatty acyl coas 1 8 0.902207955118152 0.36694640975991 |
| Wnt mediated activation of dvl 2 3 0.8982600531851881 0.3690469239658185 |
| Ephrin signaling 3 5 0.896036810350303 0.3702331036806865 |
| Cyclin d associated events in g1 4 12 0.8927135086280863 0.3720106143333028 |
| Hs gag degradation 0 3 0.8906435651944388 0.373120419621993 |
| Tnfr1 induced proapoptotic signaling 2 3 -0.8834821454577904 0.3769758251077002 |
| Maturation of sars cov 2 nucleoprotein 2 5 -0.8820385768471384 0.3777559462586177 |
| Egfr downregulation 2 8 0.8764750509779379 0.3807718337294505 |
| Purine salvage 2 4 -0.8763028846409912 0.3808653972828026 |
| Cd209 dc sign signaling 2 4 0.8701804476201351 0.3842017993335593 |
| Formation of senescence associated heterochromatin foci sahf 4 9 -0.8673601770400953 0.3857446942520819 |
| Mitochondrial calcium ion transport 5 16 0.8618007847825919 0.3887971530047913 |
| Foxo mediated transcription 4 11 -0.8608386101659914 0.3893269366862826 |
| Loss of function of mecp2 in rett syndrome 1 5 -0.8562243943856477 0.3918736717433135 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 5 15 -0.8553350070110605 0.3923657127564341 |
| Trafficking and processing of endosomal tlr 0 2 0.8529289620754827 0.3936986995748031 |
| Branched chain amino acid catabolism 10 16 -0.8528592877692805 0.3937373410454494 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 2 6 0.8487870603436577 0.395999791614908 |
| Advanced glycosylation endproduct receptor signaling 1 7 -0.842238745443526 0.3996543302356168 |
| Receptor mediated mitophagy 2 4 0.840082352919364 0.400862213855504 |
| Signalling to ras 2 3 0.8370715175180029 0.4025523692588453 |
| Signaling by ntrk3 trkc 2 3 0.8370715175180029 0.4025523692588453 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 7 10 -0.8354079082388026 0.4034880786695423 |
| Vitamin b1 thiamin metabolism 0 2 0.835311684703528 0.4035422401319377 |
| Sirt1 negatively regulates rrna expression 1 4 -0.831134792330511 0.4058974867925773 |
| Diseases of dna repair 7 11 0.8292441963883043 0.4069662406980492 |
| Apoptosis induced dna fragmentation 5 10 -0.8280885089603961 0.4076203767036555 |
| Nicotinamide salvaging 0 2 0.8271282900922767 0.4081643510291004 |
| Transcriptional regulation by tp53 24 122 -0.8263209476316994 0.4086220536994152 |
| S phase 32 98 0.8261162778221245 0.4087381346786478 |
| Defective intrinsic pathway for apoptosis 6 16 -0.8217641704872538 0.4112111293159244 |
| Chylomicron clearance 1 2 -0.8205763298709438 0.4118876348769633 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0 3 0.8183631339074561 0.4131498659749408 |
| Traf6 mediated irf7 activation 1 3 -0.8177746572489916 0.4134858714809557 |
| Sumo is proteolytically processed 1 1 -0.8172648964999487 0.4137770628996438 |
| Heme signaling 2 8 0.8166638347482663 0.4141205642120971 |
| Synthesis of 5 eicosatetraenoic acids 0 1 0.8158265698871302 0.4145993345323129 |
| Neurofascin interactions 0 1 0.8116054971469875 0.4170180359804982 |
| Generation of second messenger molecules 2 4 0.8099786656293391 0.4179524375182786 |
| Suppression of apoptosis 3 4 0.8099032281992417 0.4179957963342904 |
| Sensing of dna double strand breaks 2 4 0.8085573798298485 0.4187697884057491 |
| Gab1 signalosome 2 3 -0.807735196036233 0.4192430377429224 |
| Metabolism of angiotensinogen to angiotensins 0 1 0.8073903576343615 0.4194416204618361 |
| Runx1 regulates expression of components of tight junctions 0 2 0.7993413946099298 0.4240924825185987 |
| Synthesis of pips at the early endosome membrane 2 6 -0.7958213955860703 0.4261358540005422 |
| Cation coupled chloride cotransporters 0 1 0.7919864999349827 0.428368547952326 |
| Kinesins 5 16 -0.7919550149257036 0.4283869067949204 |
| Rna polymerase ii transcription termination 18 42 -0.7873682784783812 0.4310663106208567 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 4 13 0.7872758940315886 0.4311203779038965 |
| Camk iv mediated phosphorylation of creb 2 3 0.7867026849982717 0.4314559319472697 |
| Creb phosphorylation 1 2 0.7850220924393461 0.4324406156535247 |
| Integration of energy metabolism 6 24 -0.7840831570471913 0.4329913176902165 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 1 12 0.776719537803875 0.4373242572306974 |
| Sema4d in semaphorin signaling 3 9 -0.7766345945414096 0.4373743851712293 |
| Triglyceride metabolism 0 6 0.7758826212515577 0.4378182946785549 |
| Glycerophospholipid catabolism 0 1 0.7738894944275435 0.4389961426893816 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 3 7 -0.7730800918520137 0.4394749822947492 |
| Uptake and function of anthrax toxins 3 3 -0.7716785201422327 0.4403048557734865 |
| Pp2a mediated dephosphorylation of key metabolic factors 2 3 0.768949412214126 0.4419233423611544 |
| Interleukin 4 and interleukin 13 signaling 0 12 0.7689110951766212 0.4419460903427537 |
| Opioid signalling 6 20 -0.766019317879628 0.4436648078498537 |
| Anti inflammatory response favouring leishmania parasite infection 4 16 -0.765518649506983 0.4439627655485976 |
| Arachidonate production from dag 1 2 0.7650877443523566 0.4442192972270056 |
| Rnd1 gtpase cycle 8 16 0.7648970761935854 0.4443328351019542 |
| Activated ntrk2 signals through cdk5 1 2 -0.763110887955489 0.4453972672078834 |
| Pre notch expression and processing 2 10 -0.7586985580215023 0.4480328996962719 |
| Clec7a dectin 1 induces nfat activation 0 2 0.7523023365770386 0.4518692630303924 |
| Abacavir transport and metabolism 0 2 0.7512666778085559 0.4524921790126837 |
| Acyl chain remodelling of pc 1 1 -0.7444335970893581 0.4566141997147117 |
| Notch1 intracellular domain regulates transcription 2 7 -0.7442358626721629 0.4567337953509547 |
| Post translational modification synthesis of gpi anchored proteins 1 6 0.7435373912749176 0.4571563924372359 |
| Transcriptional regulation by e2f6 5 9 -0.7405969472703531 0.4589378595322846 |
| Sars cov 1 infection 4 11 -0.740508637723927 0.458991421949098 |
| Signaling by ntrk2 trkb 2 5 -0.7396922864718267 0.4594867295602107 |
| Dopamine clearance from the synaptic cleft 0 1 0.7380628738505449 0.4604762430834688 |
| Stat3 nuclear events downstream of alk signaling 4 4 -0.7371214980671575 0.4610484667376209 |
| Carnitine metabolism 3 5 -0.7332955999831146 0.4633781580964471 |
| Activation of rac1 3 4 0.7307368807058412 0.4649398838836929 |
| Serine biosynthesis 2 2 -0.7307327220473323 0.4649424245198896 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 2 4 -0.7295451147464158 0.4656682815667834 |
| Diseases of programmed cell death 8 26 -0.7292941726156966 0.465821736126528 |
| Assembly of collagen fibrils and other multimeric structures 0 3 0.7274688402782117 0.4669387968101115 |
| Tlr3 mediated ticam1 dependent programmed cell death 0 1 0.7271424448974634 0.4671386996338706 |
| Trif mediated programmed cell death 0 1 0.7271424448974634 0.4671386996338706 |
| Trp channels 0 1 0.7271424448974634 0.4671386996338706 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 5 17 -0.7271355352640513 0.4671429319935294 |
| Runx2 regulates osteoblast differentiation 1 3 -0.7264309661786617 0.467574613507586 |
| Ras processing 1 4 0.7243499235796456 0.4688509347757033 |
| Downregulation of erbb2 erbb3 signaling 1 2 -0.7242859430489352 0.4688902051045458 |
| Trna modification in the nucleus and cytosol 3 19 -0.7222465965142877 0.4701428797059774 |
| Oncogene induced senescence 1 7 0.7204937446934778 0.4712210497473663 |
| Synaptic adhesion like molecules 0 6 0.7203297286373219 0.4713220049053683 |
| Recognition and association of dna glycosylase with site containing an affected purine 0 2 0.719494982379077 0.4718359927054327 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0 4 0.7119241738181347 0.4765117318468312 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 4 14 -0.7087615533418112 0.4784724599737409 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 2 5 0.7080190228978642 0.4789334443297628 |
| Beta catenin phosphorylation cascade 2 5 0.7080190228978642 0.4789334443297628 |
| Signaling by ctnnb1 phospho site mutants 2 5 0.7080190228978642 0.4789334443297628 |
| Rna polymerase i promoter escape 3 13 -0.7078615498856529 0.4790312392871092 |
| Separation of sister chromatids 24 106 0.7071180322750265 0.4794931308657824 |
| Organic anion transporters 0 2 0.70703252003177 0.47954626876921 |
| Proton coupled monocarboxylate transport 1 2 0.7051231029711428 0.4807336302766902 |
| Cytosolic sulfonation of small molecules 1 5 0.6940076829711216 0.4876773907498348 |
| Pd 1 signaling 2 2 -0.6937674917421409 0.4878280324314854 |
| Repression of wnt target genes 1 4 -0.6895633506822604 0.4904688214468318 |
| Gap junction trafficking and regulation 3 10 -0.6878783414707151 0.4915293966589042 |
| Aggrephagy 5 13 -0.6867980155712796 0.492210020485182 |
| Chondroitin sulfate dermatan sulfate metabolism 1 3 0.6839255122357497 0.4940222030998549 |
| Signaling by tgfb family members 12 20 -0.6752922777597967 0.4994900891563358 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 2 8 0.672169671364657 0.501475686402554 |
| Syndecan interactions 1 4 0.6688709542757628 0.5035777999395619 |
| Rho gtpases activate nadph oxidases 1 5 -0.6672092997121192 0.5046384517228693 |
| Synthesis of ip3 and ip4 in the cytosol 2 3 0.6655347214583386 0.5057085431587709 |
| Gap junction degradation 2 6 -0.6602498432651783 0.5090935112418313 |
| Calnexin calreticulin cycle 4 8 -0.6564263280533571 0.5115498550725581 |
| Interleukin 35 signalling 2 3 -0.6555213031423252 0.5121321751593535 |
| Interleukin 27 signaling 2 3 -0.6555213031423252 0.5121321751593535 |
| Tysnd1 cleaves peroxisomal proteins 1 5 0.6552204603142684 0.5123258229721632 |
| Signaling by cytosolic fgfr1 fusion mutants 7 8 -0.6549010942043856 0.512531435704334 |
| Binding of tcf lef ctnnb1 to target gene promoters 1 1 -0.654270578369085 0.5129374975998164 |
| Runx3 regulates wnt signaling 1 1 -0.654270578369085 0.5129374975998164 |
| Rora activates gene expression 1 3 -0.6513375712743043 0.5148286002477476 |
| Fructose metabolism 1 3 -0.6507444443824101 0.5152114680635043 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0 5 0.6490167428579894 0.5163275542723751 |
| Formation of the early elongation complex 1 14 -0.6488950567456718 0.5164062100940245 |
| Displacement of dna glycosylase by apex1 0 4 0.6488221622862265 0.5164533308005621 |
| Signaling by notch1 3 10 -0.6481388785914338 0.5168951299131905 |
| Glutathione conjugation 10 14 -0.648030673185556 0.5169651115611571 |
| Diseases of glycosylation 7 22 0.6471091240927556 0.517561320569403 |
| Ovarian tumor domain proteases 5 11 -0.6464229093607307 0.5180055077692871 |
| Runx2 regulates bone development 1 4 -0.6460132706464556 0.5182707610961788 |
| Signaling by tgf beta receptor complex 11 19 -0.6443177112303337 0.5193694329530589 |
| Early phase of hiv life cycle 1 7 -0.6414287323901062 0.521244170267912 |
| Atf6 atf6 alpha activates chaperone genes 1 2 -0.6368770951323666 0.5242049034025529 |
| Scavenging by class a receptors 1 2 -0.6368770951323666 0.5242049034025529 |
| Atf6 atf6 alpha activates chaperones 1 2 -0.6368770951323666 0.5242049034025529 |
| Glycogen synthesis 1 4 0.6349916474775548 0.5254338625286747 |
| Ncam signaling for neurite out growth 2 5 0.6329000109111959 0.5267989406883187 |
| G2 m dna replication checkpoint 2 3 0.6326423147689139 0.5269672477604304 |
| Laminin interactions 1 1 -0.6299039624519012 0.528757420230173 |
| Elastic fibre formation 1 1 -0.6299039624519012 0.528757420230173 |
| Fibronectin matrix formation 1 1 -0.6299039624519012 0.528757420230173 |
| Other semaphorin interactions 1 1 -0.6299039624519012 0.528757420230173 |
| Molecules associated with elastic fibres 1 1 -0.6299039624519012 0.528757420230173 |
| Metabolism of nitric oxide nos3 activation and regulation 1 6 -0.6284654590079691 0.5296990672325483 |
| Antigen processing ubiquitination proteasome degradation 15 99 0.6243071376524445 0.5324258972935454 |
| Cytosolic trna aminoacylation 16 23 -0.6235557003860798 0.5329194112568867 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0 5 0.6203026830211421 0.535058528846811 |
| Signalling to erks 2 8 -0.6181479966092389 0.5364777861570043 |
| Tight junction interactions 0 2 0.6157232466778461 0.5380771918414016 |
| Regulation of tp53 activity through association with co factors 1 2 -0.6137652036073827 0.5393704941258948 |
| Cell cycle checkpoints 32 144 0.6129557782708556 0.5399055801995041 |
| Interleukin 6 signaling 2 3 -0.6128792903228366 0.5399561577535257 |
| Interleukin 6 family signaling 2 3 -0.6128792903228366 0.5399561577535257 |
| Interleukin 20 family signaling 2 3 -0.6128792903228366 0.5399561577535257 |
| Transcriptional regulation of white adipocyte differentiation 6 17 -0.6103805756794444 0.5416097323290974 |
| Glycosphingolipid metabolism 5 15 0.6091298307586251 0.5424383861585997 |
| Intrinsic pathway for apoptosis 9 19 -0.6075572539815141 0.5434811588166077 |
| Gpcr ligand binding 2 11 -0.6052540599924655 0.5450102008963846 |
| Golgi cisternae pericentriolar stack reorganization 2 10 0.6049695791179397 0.5451992098740066 |
| Ubiquinol biosynthesis 0 1 0.6042033541399655 0.5457084512221553 |
| Defects in cobalamin b12 metabolism 0 4 0.6014104541017783 0.5475666374298873 |
| Cobalamin cbl vitamin b12 transport and metabolism 0 4 0.6014104541017783 0.5475666374298873 |
| Downregulation of smad2 3 smad4 transcriptional activity 3 6 -0.6006799687616255 0.548053163322684 |
| Sialic acid metabolism 1 4 0.600003191664516 0.548504108419902 |
| Irak1 recruits ikk complex 1 2 0.5969930763317228 0.5505120031825661 |
| Pyruvate metabolism and citric acid tca cycle 20 33 -0.5943643320290536 0.5522684592535407 |
| Constitutive signaling by akt1 e17k in cancer 1 5 0.5934619083142644 0.5528720681032433 |
| Diseases of carbohydrate metabolism 3 9 0.5892956238315109 0.5556629799852499 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 2 8 -0.5892921508347446 0.5556653093436088 |
| Activation of the tfap2 ap 2 family of transcription factors 0 1 0.5889339336146057 0.5559055932381427 |
| Erks are inactivated 2 6 0.5866177592409806 0.5574604526419162 |
| Dscam interactions 1 3 0.5850761140462034 0.5584965389198362 |
| Role of second messengers in netrin 1 signaling 0 1 0.5838770801862995 0.5593030144500384 |
| Egfr interacts with phospholipase c gamma 0 1 0.5838770801862995 0.5593030144500384 |
| Phospholipase c mediated cascade fgfr2 0 1 0.5838770801862995 0.5593030144500384 |
| Phospholipase c mediated cascade fgfr4 0 1 0.5838770801862995 0.5593030144500384 |
| Transport of fatty acids 1 1 -0.5833574380002241 0.5596527035795498 |
| Acyl chain remodeling of cl 1 3 -0.5806335252936003 0.5614874722608729 |
| Fasl cd95l signaling 0 1 0.5775795701364521 0.5635480032589433 |
| Formation of atp by chemiosmotic coupling 3 9 0.57491703794474 0.5653474063932338 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 1 3 0.57170697654009 0.5675205072122536 |
| Signaling by insulin receptor 2 15 0.5702141476816747 0.5685324615870817 |
| Signaling by fgfr 1 19 -0.5696040814576199 0.568946259595648 |
| Signaling by fgfr2 1 19 -0.5696040814576199 0.568946259595648 |
| Synthesis of pips at the golgi membrane 4 8 0.5654356514465491 0.571777481044504 |
| Interleukin 17 signaling 8 15 0.5607052093775909 0.5749985153297803 |
| Rnd3 gtpase cycle 7 20 0.5581676902479753 0.5767298814737023 |
| Signaling by met 6 17 -0.5569880162661818 0.5775356169285559 |
| Chylomicron assembly 1 2 -0.55668902918822 0.5777399138493089 |
| Translation of sars cov 1 structural proteins 3 7 -0.5518756639369826 0.5810335428435751 |
| Keratan sulfate biosynthesis 0 2 0.5504993858623267 0.5819768980000963 |
| Synthesis of pe 0 2 0.5483790889993108 0.583431631740186 |
| Hyaluronan metabolism 3 4 -0.5467788143203263 0.584530699695601 |
| Hyaluronan uptake and degradation 3 4 -0.5467788143203263 0.584530699695601 |
| Late endosomal microautophagy 1 6 -0.5464024565619858 0.5847893218563636 |
| Nuclear events kinase and transcription factor activation 6 12 0.5453046267177323 0.5855440225277493 |
| Translation of replicase and assembly of the replication transcription complex 0 1 0.5452660360540453 0.5855705598193721 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 2 3 0.5410580156709697 0.5884675952631429 |
| Signaling by fgfr in disease 3 19 -0.5386230052864653 0.5901470104086532 |
| Hdacs deacetylate histones 6 13 -0.5384492324275486 0.5902669450703586 |
| Downstream signal transduction 3 6 -0.5373775785978769 0.591006827701337 |
| Signaling by pdgf 3 6 -0.5373775785978769 0.591006827701337 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 1 5 -0.5347749625922807 0.5928054781940961 |
| Incretin synthesis secretion and inactivation 1 5 -0.5347749625922807 0.5928054781940961 |
| Molybdenum cofactor biosynthesis 0 3 0.5344331225907626 0.5930419078435756 |
| Aflatoxin activation and detoxification 2 2 -0.531826480933099 0.5948461802715843 |
| Alpha oxidation of phytanate 3 5 0.5309976721230777 0.5954203923086019 |
| Recycling of eif2 gdp 4 8 -0.5287307761842385 0.5969922244581669 |
| Endosomal sorting complex required for transport escrt 0 6 0.5276264977474019 0.5977585979795867 |
| Formation of xylulose 5 phosphate 1 3 -0.5265966173365346 0.5984737415261174 |
| Loss of mecp2 binding ability to the ncor smrt complex 1 2 -0.5260903123832488 0.5988254593017952 |
| Nrage signals death through jnk 1 8 0.5257237307427778 0.5990801731622479 |
| Wnt5a dependent internalization of fzd4 2 9 -0.5229522843505499 0.601007458764758 |
| Transport of vitamins nucleosides and related molecules 2 7 -0.5227489482741442 0.6011489704679229 |
| Mtorc1 mediated signalling 2 11 -0.5195716748957904 0.6033621445172994 |
| Map2k and mapk activation 2 11 -0.5190555633811124 0.6037219948410328 |
| Synthesis of ip2 ip and ins in the cytosol 0 5 0.5164502477318783 0.6055399789288489 |
| Metabolism of steroid hormones 1 7 0.5150071933819843 0.6065479933443703 |
| Oxidative stress induced senescence 3 14 -0.5133086980468317 0.6077354005657636 |
| Mecp2 regulates transcription factors 0 1 0.5113169009802314 0.6091291723735448 |
| G alpha i signalling events 7 26 -0.5106978412699652 0.6095626525644182 |
| Pregnenolone biosynthesis 2 5 -0.5103346375592729 0.6098170401652163 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0 6 0.5092317644318938 0.6105897805525913 |
| Metabolism of ingested semet sec mesec into h2se 1 2 -0.5090160000850928 0.6107410090479366 |
| Diseases of base excision repair 0 1 0.5077339697912409 0.6116399220889914 |
| G alpha q signalling events 2 12 -0.4977130502372295 0.6186863085044847 |
| Protein protein interactions at synapses 2 14 0.4957660010981404 0.6200595148651951 |
| Estrogen biosynthesis 0 1 0.4935108783739104 0.6216516552881473 |
| Tyrosine catabolism 1 2 -0.4906134860965928 0.6236998461649661 |
| Gluconeogenesis 7 20 -0.4889708495545669 0.6248623346773359 |
| Rna polymerase iii transcription termination 5 6 0.4874117322287823 0.625966581005474 |
| Signaling by notch2 1 2 -0.4858932679363615 0.627042841724494 |
| Notch2 activation and transmission of signal to the nucleus 1 2 -0.4858932679363615 0.627042841724494 |
| Methylation 3 7 -0.482760262435231 0.6292659690158284 |
| Cd28 dependent pi3k akt signaling 0 2 0.4798608991694426 0.6313263060742329 |
| Dap12 signaling 1 3 0.4764996912392003 0.6337184272637317 |
| Plasma lipoprotein remodeling 1 2 -0.4754096965461982 0.6344949844454053 |
| Dag and ip3 signaling 4 8 0.4739027563965102 0.6355692535325268 |
| Deubiquitination 15 99 0.4736029239529895 0.6357830900026691 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 2 12 -0.4730074910423574 0.6362078347729665 |
| Apoptotic cleavage of cell adhesion proteins 0 6 0.4715219622449594 0.6372680398849648 |
| Inactivation of cdc42 and rac1 0 3 0.4684620115208665 0.6394542312391045 |
| Diseases associated with glycosylation precursor biosynthesis 0 9 0.4628034358576118 0.6435052682350735 |
| Gpvi mediated activation cascade 2 6 -0.4596471361849031 0.6457695198469136 |
| Eph ephrin mediated repulsion of cells 5 13 -0.4572679585093961 0.6474784571432604 |
| Josephin domain dubs 1 2 -0.4555578975100035 0.648707924721561 |
| Ldl clearance 2 14 -0.4543045518353619 0.6496096403299494 |
| Telomere c strand synthesis initiation 1 3 -0.4542648928392163 0.6496381812587144 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0 3 0.4515106302300236 0.6516215652752995 |
| Synthesis secretion and deacylation of ghrelin 0 3 0.4515106302300236 0.6516215652752995 |
| Release of apoptotic factors from the mitochondria 1 1 -0.4512827453532158 0.6517857791571726 |
| Vitamin d calciferol metabolism 1 3 0.4504903222949745 0.6523569307762618 |
| Bile acid and bile salt metabolism 2 6 -0.4464861290936589 0.6552461300093062 |
| Synthesis of bile acids and bile salts 2 6 -0.4464861290936589 0.6552461300093062 |
| Transcriptional regulation by mecp2 4 15 -0.4451071369829477 0.6562423313850292 |
| Interleukin 3 interleukin 5 and gm csf signaling 3 7 -0.4442124389569365 0.6568889998325704 |
| Grb2 events in erbb2 signaling 0 1 0.4440283233984851 0.657022106495706 |
| Signaling by fgfr3 fusions in cancer 0 1 0.4440283233984851 0.657022106495706 |
| Interleukin receptor shc signaling 0 1 0.4440283233984851 0.657022106495706 |
| Egfr transactivation by gastrin 0 1 0.4440283233984851 0.657022106495706 |
| Activated ntrk3 signals through ras 0 1 0.4440283233984851 0.657022106495706 |
| Activated ntrk2 signals through pi3k 0 1 0.4440283233984851 0.657022106495706 |
| Activated ntrk2 signals through ras 0 1 0.4440283233984851 0.657022106495706 |
| Sos mediated signalling 0 1 0.4440283233984851 0.657022106495706 |
| Shc related events triggered by igf1r 0 1 0.4440283233984851 0.657022106495706 |
| Pi3k events in erbb2 signaling 0 1 0.4440283233984851 0.657022106495706 |
| Shc mediated cascade fgfr3 0 1 0.4440283233984851 0.657022106495706 |
| Shc1 events in erbb2 signaling 0 1 0.4440283233984851 0.657022106495706 |
| Shc1 events in egfr signaling 0 1 0.4440283233984851 0.657022106495706 |
| Shc mediated cascade fgfr4 0 1 0.4440283233984851 0.657022106495706 |
| Shc1 events in erbb4 signaling 0 1 0.4440283233984851 0.657022106495706 |
| Shc mediated cascade fgfr1 0 1 0.4440283233984851 0.657022106495706 |
| Ptk6 regulates proteins involved in rna processing 1 2 0.4429571797933168 0.6577967073307995 |
| Scavenging by class f receptors 1 4 -0.4426088293093796 0.6580486973195225 |
| Diseases of immune system 0 2 0.4393962242602587 0.6603744618991729 |
| Condensation of prometaphase chromosomes 6 10 0.4391871950288477 0.6605259026020529 |
| Mitochondrial trna aminoacylation 9 17 -0.4366403036254875 0.6623722286804374 |
| Rho gtpases activate pkns 11 19 -0.4357040628314937 0.6630514576136188 |
| Activation of ampk downstream of nmdars 1 5 -0.4353218166406608 0.6633288513039064 |
| Rna polymerase i transcription termination 2 10 -0.4328448509399691 0.6651274872553015 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 1 3 -0.4319794862649141 0.66575632262431 |
| Nade modulates death signalling 2 2 -0.4306540979527573 0.6667198994892487 |
| Regulation of signaling by cbl 2 4 -0.4300472081856669 0.6671613010211217 |
| Robo receptors bind akap5 1 2 -0.4269401598575419 0.6694229135907532 |
| Fatty acyl coa biosynthesis 3 17 0.4244220644851909 0.6712580320548911 |
| Regulation of runx1 expression and activity 0 3 0.4223291427678341 0.6727847893744598 |
| Signaling by alk 1 5 -0.4222671160980238 0.6728300575945463 |
| Intraflagellar transport 3 11 -0.4170955206864574 0.676608541159706 |
| Pexophagy 0 2 0.4167212084525773 0.6768823397185695 |
| Rna polymerase iii transcription initiation from type 3 promoter 4 5 0.4155972975797987 0.6777047045040161 |
| Rna polymerase iii chain elongation 4 5 0.4155972975797987 0.6777047045040161 |
| Mitochondrial translation 23 54 -0.4140116209528938 0.6788655961858756 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 2 4 -0.4136573530564353 0.6791250639698303 |
| The citric acid tca cycle and respiratory electron transport 30 92 -0.4113668896237491 0.680803528676112 |
| Metabolism of amino acids and derivatives 61 195 -0.4106091005564392 0.6813591895299429 |
| Cdt1 association with the cdc6 orc origin complex 9 41 0.4081400452527921 0.6831708617092662 |
| Galactose catabolism 2 3 -0.4077357331279762 0.6834677004844194 |
| Mapk1 erk2 activation 2 3 -0.4006118602215774 0.6887059122518229 |
| Synthesis of pips at the plasma membrane 2 10 -0.3984719078448992 0.6902823618099152 |
| Signaling by erbb4 3 7 -0.3941561593404004 0.6934657508391304 |
| Caspase activation via death receptors in the presence of ligand 1 3 -0.3940749968102228 0.6935256701472456 |
| Regulation by c flip 1 3 -0.3940749968102228 0.6935256701472456 |
| Phenylalanine metabolism 2 3 -0.3926254236638005 0.6945961591015313 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 3 9 -0.3920685174530133 0.6950075884886817 |
| Nrcam interactions 1 2 -0.3902862384296455 0.696324898201242 |
| Ionotropic activity of kainate receptors 1 2 -0.3902862384296455 0.696324898201242 |
| Toll like receptor tlr1 tlr2 cascade 8 18 0.3896167839711504 0.696819939247387 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 2 2 -0.3847086504572504 0.7004532854373042 |
| Inla mediated entry of listeria monocytogenes into host cells 2 2 -0.3847086504572504 0.7004532854373042 |
| Asparagine n linked glycosylation 34 127 0.3837663756626451 0.7011516116371761 |
| Mapk3 erk1 activation 2 3 -0.379956762638605 0.703977510844163 |
| Gp1b ix v activation signalling 2 2 -0.3798205772784686 0.7040786065697291 |
| Notch4 activation and transmission of signal to the nucleus 2 2 -0.3798205772784686 0.7040786065697291 |
| Defective lfng causes scdo3 0 1 0.3791438799403988 0.7045810230208307 |
| Notch2 intracellular domain regulates transcription 0 1 0.3791438799403988 0.7045810230208307 |
| Degradation of axin 8 38 0.3730267741365541 0.7091285169614594 |
| Regulation of tnfr1 signaling 3 7 -0.3724405948371633 0.7095648340078398 |
| Rmts methylate histone arginines 8 19 -0.3723068067271982 0.7096644312863183 |
| Parasite infection 5 20 0.3709422136907391 0.7106805726069405 |
| Regulation of runx3 expression and activity 8 38 0.3689213785079051 0.712186327882302 |
| B wich complex positively regulates rrna expression 8 18 -0.3679093357869757 0.7129408387908558 |
| Asymmetric localization of pcp proteins 8 39 0.3669626766295309 0.7136468584732898 |
| Raf independent mapk1 3 activation 2 6 -0.3668038733146344 0.7137653182423083 |
| Abacavir metabolism 0 1 0.3667869053978362 0.7137779759145457 |
| Cd163 mediating an anti inflammatory response 1 2 0.3649717396180393 0.7151325017977481 |
| P38mapk events 1 2 0.3649717396180229 0.7151325017977603 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 1 2 0.3649717396180137 0.7151325017977672 |
| Inactivation of csf3 g csf signaling 2 6 0.3638237004906715 0.7159896633500298 |
| Tp53 regulates transcription of death receptors and ligands 1 2 -0.3632200528985217 0.7164405090389177 |
| G0 and early g1 1 5 0.3624994935792263 0.716978801900177 |
| P75ntr negatively regulates cell cycle via sc1 2 2 -0.3621155477413701 0.7172656855601549 |
| Coenzyme a biosynthesis 1 3 -0.3583366600814515 0.7200913863557112 |
| Piwi interacting rna pirna biogenesis 0 9 0.3572945550601212 0.7208713057774219 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0 8 0.3570241654192249 0.7210737149536608 |
| Insulin processing 3 8 0.3566867610267928 0.7213263176592692 |
| Vegfr2 mediated cell proliferation 1 2 0.3560067526697661 0.7218355081608088 |
| Erythropoietin activates phospholipase c gamma plcg 1 2 0.3560067526697457 0.7218355081608241 |
| Signaling by notch3 0 6 0.3558890983689894 0.7219236202596426 |
| Caspase activation via extrinsic apoptotic signalling pathway 2 4 -0.3549810972448318 0.7226037524518798 |
| Cytochrome c mediated apoptotic response 3 4 -0.3538096236941786 0.7234815607600322 |
| Netrin 1 signaling 4 8 0.3531060119098461 0.7240089659825051 |
| Rac3 gtpase cycle 12 33 0.3527619806996508 0.7242668886549353 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 1 2 0.3523040467335728 0.7246102536035548 |
| Nef mediated downregulation of mhc class i complex cell surface expression 3 3 -0.3461561418631488 0.7292253732237333 |
| Dna replication 13 93 0.3460678828177088 0.7292916996280452 |
| Vitamin b5 pantothenate metabolism 1 6 -0.3431391325384384 0.7314937928000276 |
| Nuclear signaling by erbb4 2 4 -0.3424234496954065 0.7320322436573179 |
| Tp53 regulates transcription of cell cycle genes 6 15 -0.3411184397968698 0.7330144199340913 |
| Sensory perception 5 26 -0.3410716385847369 0.733049651584476 |
| Pyruvate metabolism 5 15 -0.3404963533274079 0.7334827685356833 |
| Metabolism of polyamines 8 40 0.3382046609497698 0.7352089636742474 |
| Ub specific processing proteases 14 80 0.337995343779093 0.7353666966386712 |
| Toll like receptor 9 tlr9 cascade 11 19 0.3352471737550884 0.7374386393535508 |
| Scf skp2 mediated degradation of p27 p21 10 42 0.3352062062422572 0.7374695406939968 |
| Wax and plasmalogen biosynthesis 1 4 0.3338223245879823 0.7385136362596225 |
| Fcgr3a mediated il10 synthesis 1 7 0.3316954369738911 0.7401192465707169 |
| Cellular response to hypoxia 9 42 0.3300933978532279 0.7413293916620654 |
| Association of tric cct with target proteins during biosynthesis 10 18 -0.3296680852525226 0.7416507710819191 |
| Regulation of pten gene transcription 4 20 -0.3293361229570878 0.7419016434257542 |
| Synthesis of dna 13 87 0.3279695658809167 0.7429346739362708 |
| Degradation of dvl 8 39 0.3276505825831246 0.743175871813655 |
| Sealing of the nuclear envelope ne by escrt iii 1 6 -0.3242082329122842 0.7457803894735542 |
| Signaling by flt3 fusion proteins 2 5 0.3231410677436985 0.7465884096279258 |
| Suppression of phagosomal maturation 1 7 0.323013072524333 0.7466853418666597 |
| Rnd2 gtpase cycle 6 16 0.321995421285404 0.7474561632347312 |
| Sulfur amino acid metabolism 2 10 0.3217167569406243 0.747667282025748 |
| Regulation of mecp2 expression and activity 2 11 0.3209502254414426 0.7482481112685446 |
| Signaling by erbb2 in cancer 3 5 0.3204574035442215 0.7486216161281536 |
| Signaling by erbb2 ecd mutants 3 5 0.3204574035442215 0.7486216161281536 |
| Rho gtpases activate cit 4 10 -0.3203445447692921 0.7487071589860637 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 7 16 -0.3180014241447038 0.7504838566319432 |
| Akt phosphorylates targets in the nucleus 0 1 0.3176573012826494 0.750744903416324 |
| Regulation of gene expression in beta cells 0 1 0.3176573012826494 0.750744903416324 |
| Runx2 regulates genes involved in cell migration 0 1 0.3176573012826494 0.750744903416324 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 3 6 -0.3172544839439127 0.7510505112604271 |
| Nuclear receptor transcription pathway 1 3 -0.3145459730274592 0.7531064054901091 |
| Formation of the beta catenin tcf transactivating complex 5 11 -0.3138713343101085 0.7536187628782631 |
| Maturation of protein 3a 0 1 0.3129594114836195 0.7543114991625015 |
| Mastl facilitates mitotic progression 3 5 0.3128871623820273 0.7543663911860614 |
| Hiv transcription elongation 4 22 -0.312497039217173 0.7546628128447552 |
| Retrograde transport at the trans golgi network 4 13 -0.3121468792455365 0.754928900624003 |
| Collagen formation 2 12 0.3118760515821089 0.7551347234555281 |
| Cyclin a cdk2 associated events at s phase entry 10 44 0.3111716611553608 0.7556701254509359 |
| Map3k8 tpl2 dependent mapk1 3 activation 1 4 -0.3108174254847387 0.755939421752847 |
| G protein mediated events 4 11 -0.3099603196209173 0.7565911315933322 |
| Rho gtpases activate wasps and waves 2 15 0.3097742072624156 0.7567326670630241 |
| Rap1 signalling 1 3 -0.3093968138449315 0.7570196937618932 |
| Glycerophospholipid biosynthesis 9 33 0.3080944212289613 0.7580104861162194 |
| Vxpx cargo targeting to cilium 3 8 0.3070753109784056 0.758786049417326 |
| Influenza infection 33 125 -0.3056388559407008 0.7598796325003221 |
| The phototransduction cascade 1 5 -0.3053691263954474 0.7600850330704174 |
| Trna aminoacylation 22 36 -0.3052894135227265 0.7601457381120622 |
| Notch3 activation and transmission of signal to the nucleus 0 3 0.3030069553139083 0.7618845610558931 |
| Protein repair 1 1 -0.3009100711951675 0.7634830703421991 |
| Rhoa gtpase cycle 18 47 0.2995538171344266 0.76451751580652 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 1 2 -0.2993956105111933 0.7646382109649603 |
| Caspase mediated cleavage of cytoskeletal proteins 3 7 0.2993294592627084 0.7646886791655914 |
| Signaling by mras complex mutants 0 3 0.2966782449192807 0.7667121676823978 |
| Metabolism of folate and pterines 1 10 0.2954173040494078 0.7676751161402948 |
| Nef mediated cd8 down regulation 6 6 -0.2939317893211636 0.7688100261369659 |
| Nef mediated cd4 down regulation 6 6 -0.2939317893211636 0.7688100261369659 |
| Trafficking of glur2 containing ampa receptors 6 6 -0.2939317893211636 0.7688100261369659 |
| Traf6 mediated nf kb activation 1 6 -0.2917034579523989 0.7705133650956537 |
| Darpp 32 events 3 9 -0.291282873408216 0.770834984870163 |
| Mitochondrial fatty acid beta oxidation 7 18 -0.2894213611854274 0.7722589502767097 |
| Energy dependent regulation of mtor by lkb1 ampk 1 7 -0.2886535048435354 0.7728465464705558 |
| Role of lat2 ntal lab on calcium mobilization 0 2 0.2868397464176476 0.7742350278708268 |
| Rna polymerase i transcription 4 22 -0.2865318617098809 0.7744707938397888 |
| Alk mutants bind tkis 4 7 -0.2865099069222599 0.7744876067451765 |
| Regulation of hmox1 expression and activity 9 49 0.2852927824389462 0.7754198419756166 |
| Circadian clock 5 12 -0.2832036508609986 0.7770207298911771 |
| Na cl dependent neurotransmitter transporters 1 1 -0.2781799189737635 0.780874249061156 |
| Degradation of cysteine and homocysteine 0 4 0.2781054879432747 0.7809313830903348 |
| Programmed cell death 11 99 0.2776056669194191 0.7813150815024321 |
| Hats acetylate histones 18 25 -0.2772005536184193 0.7816261145540364 |
| Signaling by fgfr4 in disease 1 2 0.2746529501906821 0.7835828817003214 |
| Cdc42 gtpase cycle 12 32 0.2720840423953363 0.7855573991747773 |
| Signaling by nuclear receptors 13 56 -0.2700579461540828 0.787115674508994 |
| Transcriptional regulation of granulopoiesis 1 7 -0.2669990432507129 0.7894698977350219 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 1 5 -0.2663215909561799 0.7899915461902207 |
| Hedgehog on state 8 42 0.2660464984116965 0.7902033984699466 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 5 12 -0.2658970906991353 0.7903184657548836 |
| Rac2 gtpase cycle 12 33 0.2653282332778878 0.7907566166746365 |
| Smac xiap regulated apoptotic response 2 2 -0.2650081669210624 0.7910031703933587 |
| Toll like receptor cascades 14 24 0.2648984984068396 0.7910876551245112 |
| Auf1 hnrnp d0 binds and destabilizes mrna 8 42 0.2633351282496114 0.7922922864369228 |
| Defective ripk1 mediated regulated necrosis 1 2 -0.2614453186321588 0.7937491127137153 |
| Wnt ligand biogenesis and trafficking 1 6 0.2601392596294447 0.7947563552953589 |
| Signaling by hippo 4 6 -0.2599836972785495 0.7948763490002022 |
| Mtor signalling 2 15 -0.2599005763219338 0.7949404667058808 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 1 4 0.2596174219790608 0.7951588962271918 |
| Glutamate neurotransmitter release cycle 1 3 -0.2590301713240948 0.7956119613875758 |
| Degradation of gli1 by the proteasome 8 42 0.2586834564317946 0.7958794850510029 |
| Formyl peptide receptors bind formyl peptides and many other ligands 0 3 0.2561604836991163 0.797826920254292 |
| Mapk6 mapk4 signaling 9 49 0.2558896446604895 0.7980360508504392 |
| Cd28 dependent vav1 pathway 4 5 0.2552701013581393 0.7985144907944515 |
| Cross presentation of soluble exogenous antigens endosomes 8 39 0.2550100685827841 0.7987153226654573 |
| Transcriptional regulation by runx3 8 42 0.2541534665968975 0.7993769987011454 |
| Apoptotic factor mediated response 6 6 -0.2533823452249117 0.7999727690855847 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 9 9 -0.2533435439798597 0.8000027501078859 |
| G2 m checkpoints 13 86 0.252157694985802 0.8009191761815082 |
| Translation 87 220 -0.2508218456491073 0.8019518509741683 |
| Regulation of ras by gaps 8 41 0.2503907938371817 0.8022851483701727 |
| N glycan trimming in the er and calnexin calreticulin cycle 5 15 -0.2484649076575027 0.8037747185239699 |
| Amino acid transport across the plasma membrane 3 4 0.2472216942943555 0.8047366566827052 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 1 2 0.2464564002713838 0.805328951178643 |
| Phase 0 rapid depolarisation 1 2 0.2464564002713838 0.805328951178643 |
| Hur elavl1 binds and stabilizes mrna 0 4 0.2461954687332118 0.8055309230584322 |
| Activated notch1 transmits signal to the nucleus 1 3 -0.2442447694466095 0.8070412557645592 |
| Fbxw7 mutants and notch1 in cancer 0 2 0.2436052115063361 0.8075365916803703 |
| Myd88 independent tlr4 cascade 11 19 0.2427791740218542 0.8081764696927409 |
| Negative regulation of notch4 signaling 8 41 0.2412040478748392 0.8093969737591005 |
| Vitamin c ascorbate metabolism 2 3 -0.2411908243620316 0.8094072221126571 |
| Insulin receptor signalling cascade 2 6 -0.2411449652002459 0.8094427636710277 |
| G1 s dna damage checkpoints 9 42 0.239755070851432 0.8105201393984216 |
| E2f mediated regulation of dna replication 3 11 0.2394653669053068 0.8107447485172232 |
| Stabilization of p53 8 41 0.235490570102979 0.8138279970553015 |
| Sema4d induced cell migration and growth cone collapse 2 7 0.2332988117099682 0.815529381269642 |
| Defective cftr causes cystic fibrosis 9 43 0.2307828247413064 0.8174835249583179 |
| The role of nef in hiv 1 replication and disease pathogenesis 11 11 -0.2300984191850018 0.8180152932482581 |
| Synthesis of gdp mannose 0 4 0.2285682704494819 0.8192044882473293 |
| Cytoprotection by hmox1 13 68 0.2283736453899112 0.8193557760639323 |
| Signaling by leptin 1 2 -0.2273206763492996 0.8201743965174921 |
| Interleukin 37 signaling 1 2 -0.2273206763492996 0.8201743965174921 |
| Translesion synthesis by polk 0 10 0.2264129250119468 0.8208802762170291 |
| Fceri mediated nf kb activation 14 44 0.2246960994148745 0.8222156992420617 |
| Hiv infection 14 129 0.2205401183796662 0.825450531460501 |
| Abc transporter disorders 9 44 0.2200234306732061 0.8258529067661673 |
| Nucleotide salvage 1 7 0.2196394894209243 0.8261519341811614 |
| Regulation of pten stability and activity 8 43 0.2176154812551924 0.8277287212595947 |
| The activation of arylsulfatases 1 2 -0.2163047103173394 0.8287502376737717 |
| Noncanonical activation of notch3 0 2 0.2151312035770582 0.8296650264867862 |
| P130cas linkage to mapk signaling for integrins 0 1 0.2148212948474884 0.8299066495889582 |
| Signaling by vegf 6 25 0.2137570510988103 0.8307365190464346 |
| Maturation of sars cov 1 nucleoprotein 0 2 0.2133945412404972 0.8310192379134294 |
| Lysosome vesicle biogenesis 4 13 -0.212798735064826 0.831483950420588 |
| Depolymerisation of the nuclear lamina 3 8 0.2127583789610524 0.831515429209279 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 6 16 0.2127171874162792 0.8315475599419575 |
| Striated muscle contraction 2 6 -0.212058053733974 0.8320617437216644 |
| Dectin 1 mediated noncanonical nf kb signaling 8 42 0.2111047490291268 0.8328055345505199 |
| Hedgehog ligand biogenesis 8 41 0.2095558374876374 0.8340143508170406 |
| Initiation of nuclear envelope ne reformation 4 17 0.2091325412761524 0.8343447720628698 |
| Rhou gtpase cycle 7 17 0.2087708338564386 0.8346271408268788 |
| Activation of the pre replicative complex 8 20 0.2065937775405733 0.8363271202361973 |
| Orc1 removal from chromatin 10 51 0.2028511190598627 0.8392514012124557 |
| Platelet sensitization by ldl 3 5 0.2015448807368135 0.8402725395895922 |
| Rrna processing in the mitochondrion 4 5 -0.2012725387812014 0.8404854740406111 |
| Regulation of runx2 expression and activity 8 44 0.2011646640392346 0.8405698206778593 |
| Myoclonic epilepsy of lafora 0 1 0.2010826859831308 0.8406339200701811 |
| Rhog gtpase cycle 15 36 0.2009401153359551 0.8407453998805361 |
| Cell extracellular matrix interactions 2 8 0.1999355351901462 0.8415309984325963 |
| Mismatch repair 4 13 0.1990735305673933 0.8422052263578503 |
| Sumoylation 39 81 -0.1973089245895712 0.8435857958158821 |
| The role of gtse1 in g2 m progression after g2 checkpoint 10 49 0.1968504111144111 0.8439446004774196 |
| Metabolism of nucleotides 22 47 -0.1967482965390912 0.8440245135238895 |
| Rhobtb3 atpase cycle 1 4 -0.196292076664977 0.8443815626643032 |
| Slc mediated transmembrane transport 10 21 0.1962725113295306 0.8443968757031644 |
| Assembly of the orc complex at the origin of replication 1 8 -0.194881841318029 0.8454854501655158 |
| Crmps in sema3a signaling 2 6 0.1930525095126494 0.8469178448483963 |
| Sensory processing of sound by outer hair cells of the cochlea 3 13 -0.192538958408215 0.847320054343693 |
| Signaling by activin 0 1 0.1920425603775518 0.8477088674787034 |
| Signaling by nodal 0 1 0.1920425603775518 0.8477088674787034 |
| Estrogen stimulated signaling through prkcz 0 1 0.1920425603775518 0.8477088674787034 |
| Constitutive signaling by overexpressed erbb2 2 4 0.1908933862426688 0.8486091219072289 |
| Pre notch processing in golgi 1 4 -0.1905043252710453 0.8489139541754915 |
| Signaling by scf kit 4 8 -0.1900021996895138 0.8493074068277968 |
| Transport of mature transcript to cytoplasm 27 61 -0.1891740959588232 0.849956369508357 |
| Negative regulation of nmda receptor mediated neuronal transmission 2 6 0.1890182607465879 0.8500785047637209 |
| Protein folding 8 37 -0.1875414762240433 0.8512361072100143 |
| Formation of rna pol ii elongation complex 5 29 -0.1824644864550282 0.8552182221868554 |
| Fc epsilon receptor fceri signaling 15 52 0.1815454888623016 0.8559394313585145 |
| Cd28 co stimulation 1 9 0.1790970815708129 0.8578614735281411 |
| Fructose catabolism 1 1 -0.1784449360574252 0.8583735616946733 |
| Assembly and cell surface presentation of nmda receptors 2 10 -0.1784254775785284 0.8583888421104502 |
| Collagen biosynthesis and modifying enzymes 1 9 0.1773779489717288 0.8592115268413869 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 2 4 0.1736008888570445 0.8621791334218087 |
| Smooth muscle contraction 2 11 -0.1730595607798237 0.8626046110949288 |
| Formation of apoptosome 3 3 -0.171991317580706 0.8634443548533213 |
| Meiotic recombination 1 12 -0.1719504634208645 0.8634764732927398 |
| Role of abl in robo slit signaling 1 3 -0.1709968584340129 0.8642262358215809 |
| Tp53 regulates metabolic genes 10 34 -0.1707473475240318 0.8644224315251485 |
| Growth hormone receptor signaling 1 5 -0.1704080053706422 0.8646892768469028 |
| Regulation of expression of slits and robos 20 123 0.1700875275587103 0.8649413021613519 |
| Acyl chain remodelling of ps 0 1 0.1697816462270531 0.8651818615466431 |
| Signaling by pdgfr in disease 5 5 -0.1695063968441676 0.8653983412146564 |
| Signaling by notch4 8 44 0.1684516641197516 0.8662279666514681 |
| Mitotic g2 g2 m phases 23 86 0.1682185630245501 0.8664113378552618 |
| Metabolism of rna 114 464 -0.1672872987405033 0.8671439974525947 |
| P75ntr regulates axonogenesis 1 3 -0.1659911845995893 0.8681638876038158 |
| Sema3a pak dependent axon repulsion 3 7 0.165861109158946 0.8682662538978236 |
| Fcgamma receptor fcgr dependent phagocytosis 7 27 0.1655580151740278 0.8685047902581238 |
| Aspartate and asparagine metabolism 1 5 -0.1607008928737907 0.872328986163613 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 1 6 -0.1605290208930771 0.8724643626879653 |
| Tcr signaling 8 47 0.1603209616507806 0.8726282474343083 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 1 1 -0.1603052338600223 0.8726406361714178 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 1 1 -0.1603052338600223 0.8726406361714178 |
| Transcriptional regulation of pluripotent stem cells 1 1 -0.1603052338600223 0.8726406361714178 |
| Interleukin 10 signaling 1 1 -0.1603052338600223 0.8726406361714178 |
| Deactivation of the beta catenin transactivating complex 5 10 -0.1583795120445195 0.8741577570311241 |
| Tnfr2 non canonical nf kb pathway 8 43 0.1581333973314908 0.8743516844253678 |
| Factors involved in megakaryocyte development and platelet production 13 42 -0.1575364355348055 0.8748220949742356 |
| Nectin necl trans heterodimerization 1 1 -0.1573807323226042 0.8749447976001863 |
| Arms mediated activation 0 1 0.1564387255708235 0.8756872143343282 |
| Activation of smo 0 1 0.1546834059853928 0.8770709126311258 |
| Platelet adhesion to exposed collagen 0 2 0.1537252387020316 0.8778263837124978 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0 1 0.1535217125609052 0.8779868691190926 |
| Runx3 regulates notch signaling 0 1 0.1535217125609052 0.8779868691190926 |
| E3 ubiquitin ligases ubiquitinate target proteins 8 17 0.151327245632496 0.8797175778579669 |
| Gdp fucose biosynthesis 2 3 -0.1508049986520107 0.8801295430120477 |
| Ntrk2 activates rac1 0 1 0.1506472438973988 0.8802539914037719 |
| Activated ntrk2 signals through fyn 0 1 0.1506472438973988 0.8802539914037719 |
| Killing mechanisms 0 1 0.1506472438973988 0.8802539914037719 |
| Rhob gtpase cycle 6 25 0.1503030194086566 0.8805255509091421 |
| Mrna decay by 3 to 5 exoribonuclease 2 15 0.1495264554205752 0.8811382356125295 |
| Hdr through single strand annealing ssa 0 15 0.1494612747216372 0.8811896643872807 |
| Homologous dna pairing and strand exchange 0 15 0.1494612747216372 0.8811896643872807 |
| Tp53 regulates transcription of caspase activators and caspases 1 2 -0.1493390002363452 0.8812861425648115 |
| Cytochrome p450 arranged by substrate type 0 3 0.1482895252314985 0.882114281621224 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 8 42 0.1481398085876688 0.8822324333126168 |
| Dna damage reversal 2 5 -0.1479999513616075 0.8823428066273529 |
| Zbp1 dai mediated induction of type i ifns 1 4 0.1465419497153429 0.8834935762515617 |
| Rip mediated nfkb activation via zbp1 1 4 0.1465419497153429 0.8834935762515617 |
| Synthesis of dolichyl phosphate 1 2 -0.1463024380036113 0.883682641319762 |
| Transmission across chemical synapses 10 45 -0.1462916916959227 0.8836911243646854 |
| Rna polymerase ii transcription 59 319 -0.1449987838746062 0.884711831970773 |
| Disinhibition of snare formation 2 2 -0.1445117741635667 0.8850963596045309 |
| Grb2 sos provides linkage to mapk signaling for integrins 1 2 0.1439311724770951 0.8855548198916745 |
| Positive epigenetic regulation of rrna expression 11 28 -0.1421642603089723 0.8869502611516851 |
| Sumo is conjugated to e1 uba2 sae1 1 3 -0.1395680350207798 0.8890012977318074 |
| Processing and activation of sumo 1 3 -0.1395680350207798 0.8890012977318074 |
| Sumo is transferred from e1 to e2 ube2i ubc9 1 3 -0.1395680350207798 0.8890012977318074 |
| Synthesis of pi 1 2 -0.1393819494701446 0.88914833535981 |
| Transcriptional regulation by runx2 9 52 0.1386359844966222 0.8897378063600163 |
| Mitochondrial protein import 5 37 0.1385370349024623 0.8898160021732724 |
| M phase 46 190 0.1379592984313448 0.8902725850301845 |
| N glycan antennae elongation in the medial trans golgi 0 2 0.1374742660699048 0.8906559323026617 |
| Reactions specific to the complex n glycan synthesis pathway 0 2 0.1374742660699048 0.8906559323026617 |
| The canonical retinoid cycle in rods twilight vision 1 1 -0.1370244025755928 0.8910115065710711 |
| Downstream signaling events of b cell receptor bcr 8 43 0.1370172087316659 0.8910171927981385 |
| Rna polymerase i transcription initiation 7 19 -0.1363309309836795 0.8915596727630222 |
| Rhobtb1 gtpase cycle 2 20 -0.1360520134741233 0.8917801623918642 |
| C type lectin receptors clrs 15 51 0.1347659272752362 0.8927969461195666 |
| Dna damage telomere stress induced senescence 4 14 -0.1338305726538919 0.8935365511737305 |
| Clec7a dectin 1 signaling 14 47 0.1334793841276722 0.8938142674508658 |
| Infectious disease 62 339 -0.1319842634946162 0.894996738764402 |
| Traf3 dependent irf activation pathway 2 2 -0.1319813547415441 0.8949990394873717 |
| Rrna processing 38 168 -0.1316862151727809 0.8952324892557548 |
| Irf3 mediated activation of type 1 ifn 0 1 0.1311947922037527 0.8956212155707095 |
| Signal regulatory protein family interactions 1 3 -0.1311418254825734 0.8956631149033212 |
| Rac1 gtpase cycle 15 43 0.1308975694107513 0.8958563374688986 |
| Signaling by mapk mutants 1 2 0.1308791405303987 0.8958709161721894 |
| Activation of the ap 1 family of transcription factors 1 2 0.1308791405303987 0.8958709161721894 |
| Phase i functionalization of compounds 2 15 0.129914191766466 0.8966343160417967 |
| Esr mediated signaling 8 42 -0.1293346264466805 0.8970928735743628 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 3 8 -0.1283196844967609 0.8978959879062933 |
| Degradation of the extracellular matrix 3 10 -0.127594803647143 0.8984696436080661 |
| Interferon alpha beta signaling 3 9 -0.1272093817143261 0.8987746801741578 |
| Nf kb is activated and signals survival 0 1 0.1271649827952795 0.8988098200124508 |
| P75ntr recruits signalling complexes 0 1 0.1271649827952795 0.8988098200124508 |
| P75ntr signals via nf kb 0 1 0.1271649827952795 0.8988098200124508 |
| Selective autophagy 13 31 0.1264615844843337 0.8993665560021502 |
| Regulation of tlr by endogenous ligand 0 1 0.1261739536719759 0.8995942285290164 |
| Irak4 deficiency tlr2 4 0 1 0.1261739536719759 0.8995942285290164 |
| Signaling by erbb2 5 12 -0.1256915153342747 0.899976118382783 |
| Interleukin 1 signaling 14 48 0.1255374996155191 0.9000980394458382 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 8 53 0.1250397990604081 0.9004920424821274 |
| Plasma lipoprotein assembly remodeling and clearance 3 20 -0.1241583380339635 0.9011899083651508 |
| Recycling pathway of l1 5 19 0.1240579526000475 0.9012693898696902 |
| Akt phosphorylates targets in the cytosol 3 4 0.1238407043453151 0.901441402457326 |
| Assembly of the hiv virion 1 2 0.123198686267999 0.9019497658511342 |
| Peroxisomal protein import 6 22 0.1231397286826666 0.901996451724112 |
| Pi metabolism 2 17 -0.1225108970380367 0.9024944164125036 |
| Rhoc gtpase cycle 8 32 0.1222402606479037 0.9027087421379428 |
| Mitotic g1 phase and g1 s transition 26 78 0.1215950759043361 0.9032197134108751 |
| Switching of origins to a post replicative state 10 61 0.1213594156320977 0.9034063608580054 |
| Signaling by ptk6 5 10 0.1205837127865071 0.9040207700108212 |
| Ion homeostasis 3 12 -0.119566422635114 0.904826619712314 |
| Cardiac conduction 3 12 -0.119566422635114 0.904826619712314 |
| Ire1alpha activates chaperones 7 25 0.1190823955674011 0.905210077794144 |
| Biosynthesis of epa derived spms 0 1 0.1189488690256854 0.9053158646799108 |
| Dna replication initiation 1 5 -0.1186764601225677 0.905531686827431 |
| Protein localization 22 78 0.1179170526596628 0.9061333814454108 |
| Transcriptional activation of mitochondrial biogenesis 3 14 -0.1177655842671497 0.9062533995173756 |
| Pka mediated phosphorylation of key metabolic factors 0 1 0.1166212872972246 0.907160168008042 |
| Hdl assembly 0 1 0.1166212872972246 0.907160168008042 |
| Budding and maturation of hiv virion 5 5 -0.1166192032350482 0.9071618195798824 |
| Regulation of lipid metabolism by pparalpha 7 25 -0.1165615498860952 0.9072075087058338 |
| Neurotransmitter receptors and postsynaptic signal transmission 6 36 -0.1155967722919036 0.9079721210958556 |
| Digestion 1 1 -0.1150506047694951 0.9084050115073824 |
| Digestion and absorption 1 1 -0.1150506047694951 0.9084050115073824 |
| Snrnp assembly 15 39 -0.1142439638375173 0.9090444019238344 |
| Activation of atr in response to replication stress 6 20 0.1138838945591207 0.9093298327772236 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 5 5 -0.1137060133255546 0.9094708454974558 |
| Hedgehog off state 8 50 0.1119676088081191 0.9108490894609542 |
| Activation of nima kinases nek9 nek6 nek7 0 4 0.1115296446666439 0.9111963591916648 |
| Uptake and actions of bacterial toxins 3 8 -0.1107791599217932 0.9117914715931844 |
| Epha mediated growth cone collapse 3 10 0.1099958269751057 0.9124126844250416 |
| Apoptotic cleavage of cellular proteins 5 18 0.1097070431362225 0.9126417145216 |
| Developmental biology 49 256 -0.108909058679131 0.9132746216001786 |
| Notch4 intracellular domain regulates transcription 1 2 0.1085826854472759 0.9135334945551744 |
| Regulation of beta cell development 1 2 0.1085826854472756 0.9135334945551749 |
| Pcp ce pathway 8 51 0.1075561439138506 0.9143477871883468 |
| Anchoring of the basal body to the plasma membrane 10 26 0.1070828385771357 0.9147232617088012 |
| Nef and signal transduction 1 2 0.1069025892922244 0.9148662590067403 |
| Negative epigenetic regulation of rrna expression 6 25 -0.1068949682134558 0.914872305103519 |
| Neutrophil degranulation 47 171 0.1068806794049844 0.914883640981635 |
| Diseases of signal transduction by growth factor receptors and second messengers 18 144 -0.1057823931064617 0.9157550066663412 |
| Tp53 regulates transcription of cell death genes 2 6 -0.1045661894908849 0.916720044461133 |
| Transcription of the hiv genome 4 28 -0.1030843879712413 0.9178959956024348 |
| Free fatty acids regulate insulin secretion 2 2 -0.1026170827078814 0.9182668843754478 |
| Negative regulation of fgfr1 signaling 4 4 -0.1014287213226355 0.919210137718344 |
| Spry regulation of fgf signaling 4 4 -0.1014287213226355 0.919210137718344 |
| Negative regulation of fgfr2 signaling 4 4 -0.1014287213226355 0.919210137718344 |
| Negative regulation of fgfr3 signaling 4 4 -0.1014287213226355 0.919210137718344 |
| Negative regulation of fgfr4 signaling 4 4 -0.1014287213226355 0.919210137718344 |
| Signaling by the b cell receptor bcr 10 46 0.1010612786631904 0.919501815773896 |
| Ripk1 mediated regulated necrosis 6 12 0.1009520769395185 0.9195885028076948 |
| Regulation of bach1 activity 2 4 -0.1007057242144376 0.9197840672125968 |
| Sensory processing of sound 3 18 -0.0996820770069651 0.920596730137905 |
| Hsf1 activation 2 13 -0.0996598114382817 0.9206144074670406 |
| Signaling by moderate kinase activity braf mutants 3 13 -0.0994428085734958 0.9207866948595268 |
| Nr1h2 and nr1h3 mediated signaling 1 7 -0.0992735216517917 0.9209211012077264 |
| Metabolism of steroids 15 49 0.0991078050450179 0.9210526750712492 |
| Fatty acid metabolism 12 59 0.0988943492513346 0.9212221555574812 |
| Interleukin 21 signaling 2 2 -0.0987996433364672 0.9212973516854528 |
| Interleukin 9 signaling 2 2 -0.0987996433364672 0.9212973516854528 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0 2 0.0973895939149314 0.9224170082984042 |
| Condensation of prophase chromosomes 1 11 -0.0969543746088688 0.9227626274663472 |
| Signaling by fgfr1 5 5 -0.0965601226301824 0.9230757259868654 |
| Signaling by fgfr3 5 5 -0.0965601226301824 0.9230757259868654 |
| Signaling by fgfr4 5 5 -0.0965601226301824 0.9230757259868654 |
| Nervous system development 45 209 -0.0958292317900106 0.923656200582043 |
| Plasma lipoprotein clearance 2 16 -0.0955177854692871 0.9239035640861888 |
| Chl1 interactions 0 3 0.0955119046246052 0.9239082349662764 |
| Rhof gtpase cycle 4 18 0.0950122279743966 0.9243051143424031 |
| Interleukin 1 family signaling 14 50 0.0949791688672949 0.9243313729446389 |
| Pecam1 interactions 2 4 -0.094942218823728 0.9243607221862682 |
| Cristae formation 5 19 -0.0943064128300738 0.9248657559194736 |
| Pkmts methylate histone lysines 5 15 -0.093781220051125 0.9252829501564463 |
| Degradation of beta catenin by the destruction complex 8 49 0.0937677245562273 0.9252936707630476 |
| Class i peroxisomal membrane protein import 3 8 0.0926504164802798 0.9261812894090028 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 1 3 0.0912487239464332 0.9272949602952704 |
| Signaling by wnt in cancer 1 7 -0.0908363747138243 0.9276226066728605 |
| Integrin cell surface interactions 3 4 0.0899918403432191 0.9282936989821456 |
| P75 ntr receptor mediated signalling 3 17 -0.089984959836912 0.9282991666486776 |
| Interconversion of nucleotide di and triphosphates 5 19 -0.0880877005949928 0.9298069718810922 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 4 5 0.0865567682595265 0.9310238308018824 |
| Telomere extension by telomerase 6 11 -0.0861057413122169 0.93138235967089 |
| Fgfr1 mutant receptor activation 6 10 -0.0851467785632921 0.9321447013946876 |
| Abc family proteins mediated transport 10 53 0.0849756685757331 0.932280734393156 |
| Metabolism of vitamins and cofactors 6 50 -0.084780758590503 0.9324356908769826 |
| Hdr through mmej alt nhej 7 8 0.0839562341408522 0.9330912289560244 |
| Runx3 regulates p14 arf 1 2 0.0834746470809869 0.9334741357205336 |
| Rhod gtpase cycle 9 27 0.0821057139850255 0.934562649365505 |
| Semaphorin interactions 5 22 -0.0816589545978321 0.93491791879103 |
| Myogenesis 5 6 0.081622467066479 0.9349469347689184 |
| Oas antiviral response 1 3 -0.0812682959688935 0.9352285867192442 |
| Neurotransmitter clearance 1 2 -0.080646763831223 0.9357228751377776 |
| Sumoylation of intracellular receptors 1 2 -0.0806125559984645 0.9357500804626676 |
| Cyclin a b1 b2 associated events during g2 m transition 5 10 0.0793083738307175 0.936787345929915 |
| Chaperone mediated autophagy 1 7 -0.0775373325740232 0.9381960935538892 |
| Negative regulation of mapk pathway 1 10 -0.0769689365196735 0.9386482567034656 |
| Adherens junctions interactions 3 7 -0.0766930246548402 0.9388677537174746 |
| Formation of the cornified envelope 2 6 0.0766235296597831 0.9389230400174526 |
| Keratinization 2 6 0.0766235296597831 0.9389230400174526 |
| Rhobtb2 gtpase cycle 6 20 -0.0765599464553602 0.9389736234880096 |
| Chromatin modifying enzymes 21 73 -0.0764982232875113 0.9390227274463308 |
| Selenoamino acid metabolism 26 91 -0.0761533567646143 0.9392970907849564 |
| Activation of nmda receptors and postsynaptic events 7 22 0.0760681988023601 0.9393648404918262 |
| Neuronal system 10 53 -0.0746367936185662 0.940503698679735 |
| Ncam1 interactions 1 1 -0.0741738011964007 0.9408720920291028 |
| Cellular response to chemical stress 13 77 0.0732662357072821 0.9415942594670464 |
| Basigin interactions 3 7 0.0731614996037664 0.9416776031151152 |
| Metalloprotease dubs 1 5 0.0728765883132537 0.9419043242142826 |
| Rho gtpase effectors 18 109 -0.0726997908811658 0.9420450149631924 |
| Tnf signaling 3 9 -0.0722758827622061 0.9423823572584672 |
| Nonsense mediated decay nmd 22 86 -0.0717460985139937 0.9428039693551584 |
| Recruitment of mitotic centrosome proteins and complexes 9 28 0.071566345850151 0.9429470234944604 |
| Vldlr internalisation and degradation 7 7 -0.0713202021460259 0.9431429171822094 |
| Rho gtpases activate paks 5 11 -0.0694325327696061 0.9446453339905032 |
| Amino acids regulate mtorc1 5 12 -0.0693597649746021 0.9447032546546944 |
| Ctla4 inhibitory signaling 2 7 0.0690486594079164 0.9449508872876378 |
| Golgi associated vesicle biogenesis 13 25 0.0687041189425301 0.9452251395116904 |
| Raf activation 2 11 -0.0684037705891508 0.945464220366864 |
| Eukaryotic translation initiation 24 102 -0.0673272500019066 0.94632118373759 |
| Ksrp khsrp binds and destabilizes mrna 9 14 -0.0665657605119676 0.9469274044165452 |
| Hdr through homologous recombination hrr 1 24 0.0664543142129403 0.947016129239768 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 0 3 0.0662748544733456 0.9471590024232236 |
| Other interleukin signaling 3 3 -0.0662395587096012 0.9471871026202544 |
| Regulation of tp53 expression and degradation 3 11 -0.065755029400656 0.9475728600451034 |
| Uptake and function of diphtheria toxin 1 4 0.0656946807131051 0.9476209074424744 |
| Peptide hormone metabolism 2 14 -0.0649213925558261 0.9482365877267084 |
| Rho gtpases activate iqgaps 1 8 -0.0649197994931936 0.9482378561310072 |
| Muscle contraction 7 26 -0.064638836778655 0.9484615620742604 |
| Apc c cdc20 mediated degradation of cyclin b 7 13 0.0645881238884265 0.948501940729906 |
| Apc c mediated degradation of cell cycle proteins 9 61 0.0642831963462761 0.9487447331519518 |
| Polb dependent long patch base excision repair 0 7 0.0637343928339329 0.949181718885578 |
| Processing of smdt1 6 11 0.0636632417238121 0.9492383742005585 |
| Sars cov 2 infection 6 22 -0.0629237582693043 0.9498272159666163 |
| Platelet activation signaling and aggregation 20 57 -0.0625853270733232 0.9500967138095816 |
| Metabolism of carbohydrates 20 97 -0.0619235299354914 0.950623729274284 |
| Regulation of plk1 activity at g2 m transition 9 30 0.0610622821289899 0.951309607571902 |
| Mitotic telophase cytokinesis 5 11 -0.0609942331663646 0.9513638017727732 |
| Ras activation upon ca2 influx through nmda receptor 0 5 0.0604067397603523 0.9518316909095588 |
| Long term potentiation 0 5 0.0604067397603523 0.9518316909095588 |
| Unblocking of nmda receptors glutamate binding and activation 0 5 0.0604067397603523 0.9518316909095588 |
| Mitochondrial biogenesis 8 34 -0.060166291853355 0.9520231922629904 |
| Rna polymerase iii transcription initiation from type 1 promoter 2 10 -0.0589475499586496 0.9529938844812552 |
| Trafficking of ampa receptors 10 10 -0.0586604187651412 0.953222586269734 |
| Trna processing 31 64 -0.0582763010826382 0.9535285444225694 |
| Vitamin b2 riboflavin metabolism 1 1 -0.0580429508619978 0.9537144163346902 |
| Cellular response to starvation 20 89 -0.0578341476318989 0.9538807378132752 |
| Ngf stimulated transcription 1 3 -0.0573603134908832 0.954258176170992 |
| Regulation of pten localization 1 1 -0.0567522161801806 0.9547425785112782 |
| Regulation of kit signaling 0 3 0.0564857931558796 0.9549548128745178 |
| Phosphorylation of emi1 0 4 0.0563406534933571 0.955070433445405 |
| Uch proteinases 8 48 0.0561894898586884 0.9551908538137212 |
| Non integrin membrane ecm interactions 1 5 0.0561755411724864 0.9552019657040368 |
| Irs mediated signalling 4 4 -0.0559648254956188 0.955369828412632 |
| Signal attenuation 1 3 -0.0550273395085902 0.9561166830073184 |
| Rhoq gtpase cycle 10 25 0.0548557390201378 0.9562533938958446 |
| Antigen processing cross presentation 9 53 0.0548101659317717 0.9562897013364572 |
| Response of eif2ak1 hri to heme deficiency 3 5 -0.0546292442514179 0.956433839996802 |
| Signaling by csf3 g csf 1 8 0.0540082543058072 0.9569285878568892 |
| Transport of the slbp dependant mature mrna 13 31 -0.0536558212553176 0.9572093815957992 |
| Activation of gene expression by srebf srebp 4 19 0.0535498022585098 0.9572938510778016 |
| Erythropoietin activates ras 1 3 -0.0531065584350685 0.957647005953452 |
| Interleukin 7 signaling 0 2 0.0528455972031044 0.9578549309189603 |
| Eukaryotic translation elongation 21 77 -0.0524732872663588 0.9581515796763383 |
| Transport of mature mrnas derived from intronless transcripts 15 36 -0.0518163626534315 0.9586750175537802 |
| Response of eif2ak4 gcn2 to amino acid deficiency 19 77 -0.0516261446902511 0.9588265866635606 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 7 12 -0.0512643592214397 0.9591148679646996 |
| Dna double strand break response 4 22 -0.0501466913323099 0.9600054922151472 |
| Hiv life cycle 11 73 -0.0499016268165352 0.960200780908445 |
| Neurexins and neuroligins 1 9 0.0490447086104443 0.9608836664690964 |
| Respiratory electron transport 14 52 -0.0487599827904211 0.9611105733249156 |
| Rna polymerase iii transcription 2 11 -0.0483469748480448 0.961439717785338 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 13 61 -0.0479567399057094 0.9617507194654112 |
| Dna replication pre initiation 10 63 0.0478380580597526 0.9618453053180616 |
| Meiotic synapsis 0 13 0.0477416426492966 0.9619221458884096 |
| Processive synthesis on the lagging strand 3 14 -0.047333013759747 0.962247816385551 |
| Metabolism of water soluble vitamins and cofactors 5 42 -0.0462558617694198 0.9631063188323404 |
| Pi 3k cascade fgfr2 1 2 -0.0456636072223608 0.9635783707642588 |
| Frs mediated fgfr4 signaling 1 2 -0.0456636072223608 0.9635783707642588 |
| Activated ntrk2 signals through frs2 and frs3 1 2 -0.0456636072223608 0.9635783707642588 |
| Pi 3k cascade fgfr3 1 2 -0.0456636072223608 0.9635783707642588 |
| Frs mediated fgfr3 signaling 1 2 -0.0456636072223608 0.9635783707642588 |
| Signaling by flt3 itd and tkd mutants 1 2 -0.0456636072223608 0.9635783707642588 |
| Frs mediated fgfr2 signaling 1 2 -0.0456636072223608 0.9635783707642588 |
| Frs mediated fgfr1 signaling 1 2 -0.0456636072223608 0.9635783707642588 |
| Tie2 signaling 1 2 -0.0456636072223608 0.9635783707642588 |
| Stat5 activation 1 2 -0.0456636072223608 0.9635783707642588 |
| Pi 3k cascade fgfr4 1 2 -0.0456636072223608 0.9635783707642588 |
| Pi 3k cascade fgfr1 1 2 -0.0456636072223608 0.9635783707642588 |
| Stat5 activation downstream of flt3 itd mutants 1 2 -0.0456636072223608 0.9635783707642588 |
| Interferon signaling 19 65 -0.0456334796297131 0.9636023840729068 |
| Ret signaling 2 6 -0.0451869331473705 0.9639583094501274 |
| Glucose metabolism 17 60 -0.0443948547480454 0.9645896629233536 |
| Sars cov infections 12 60 -0.0438231533700699 0.9650453710904608 |
| Lipophagy 2 3 0.0433159254412484 0.9654496964707632 |
| Rrna modification in the nucleus and cytosol 19 58 -0.0431421661647706 0.9655882068334568 |
| Signaling by receptor tyrosine kinases 22 111 0.0430843837043474 0.9656342677386518 |
| Interleukin 12 family signaling 8 30 -0.0426996554029816 0.965940954269244 |
| Mitotic prophase 10 59 -0.0426922048254097 0.9659468935541023 |
| Ecm proteoglycans 2 3 0.0425988238045659 0.966021333108722 |
| Signaling by fgfr1 in disease 6 11 -0.0412105372794453 0.9671280532760334 |
| Rhov gtpase cycle 8 17 0.0408977522490359 0.9673774093953248 |
| Interleukin 12 signaling 7 27 -0.0406741963386874 0.9675556329056108 |
| Apc cdc20 mediated degradation of nek2a 7 14 0.0405196508670391 0.9676788407793366 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 7 14 0.0405196508670391 0.9676788407793366 |
| Linoleic acid la metabolism 0 2 0.0403729793753216 0.9677957720146948 |
| Regulation of tp53 activity 9 54 -0.0402990559851961 0.9678547063838968 |
| Ion channel transport 5 28 0.0401109812961818 0.9680046470400314 |
| Signaling by gpcr 8 48 -0.039437745763817 0.9685413865380612 |
| Cargo recognition for clathrin mediated endocytosis 4 35 -0.0393799371642615 0.9685874753239716 |
| Mhc class ii antigen presentation 12 52 -0.0393123669030753 0.968641346876183 |
| Sumoylation of dna damage response and repair proteins 19 49 -0.0392102424780252 0.9687227676009972 |
| Signaling by egfr 2 12 0.0391280800791372 0.9687882734409616 |
| Hcmv infection 18 49 -0.0389530574253421 0.9689278149313084 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 9 51 -0.0389302872056474 0.9689459691677976 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 3 3 -0.0388770517643703 0.9689884127732162 |
| Interleukin 2 family signaling 3 3 -0.0388770517643703 0.9689884127732162 |
| Epigenetic regulation of gene expression 7 44 -0.0388376749600012 0.9690198072073806 |
| Death receptor signalling 5 27 -0.038800905258101 0.96904912308791 |
| Antiviral mechanism by ifn stimulated genes 25 51 -0.0387779982583137 0.9690673864844546 |
| Diseases of metabolism 7 47 -0.0386314754080784 0.9691842072695016 |
| Chromosome maintenance 10 49 -0.0378652772350592 0.9697950979361956 |
| Perk regulates gene expression 10 16 -0.0377148271706012 0.9699150540351622 |
| Aurka activation by tpx2 8 27 0.0374530667835243 0.9701237611490414 |
| Glycolysis 15 48 -0.0374009905200001 0.970165282904027 |
| Sumoylation of chromatin organization proteins 21 37 -0.037129358361028 0.970381863574947 |
| Gene silencing by rna 5 46 -0.0370330899600237 0.9704586218556496 |
| Interleukin 15 signaling 1 2 0.0370092018308443 0.9704776687681164 |
| Hcmv early events 17 43 -0.0366513742046471 0.9707629803310256 |
| Endogenous sterols 0 2 0.0364220667242949 0.970945819149448 |
| Atf4 activates genes in response to endoplasmic reticulum stress 8 13 -0.0361670290107679 0.9711491758185428 |
| Apoptosis 11 90 0.0360531833111957 0.9712399523416396 |
| Copi independent golgi to er retrograde traffic 5 27 -0.0360304480829957 0.971258080650932 |
| Deadenylation dependent mrna decay 12 39 -0.0359934554057518 0.9712875774041738 |
| Biological oxidations 17 44 -0.0358750720890182 0.9713819726601758 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 13 13 -0.0355574180784566 0.9716352622838084 |
| Trna processing in the nucleus 17 40 -0.0354065343477818 0.9717555743243708 |
| Abc transporters in lipid homeostasis 1 3 -0.0353773898093459 0.9717788137423184 |
| Attenuation phase 10 10 -0.035275354276131 0.9718601755352174 |
| Cytosolic sensors of pathogen associated dna 7 17 0.0351954528778856 0.9719238880643436 |
| Synthesis of substrates in n glycan biosythesis 9 20 -0.0351582699354203 0.9719535374101624 |
| Telomere maintenance 11 43 -0.035138575411045 0.9719692416634884 |
| Infection with mycobacterium tuberculosis 4 13 0.0346511863799147 0.9723578851542434 |
| Response of mtb to phagocytosis 4 13 0.0346511863799147 0.9723578851542434 |
| Fanconi anemia pathway 6 7 0.0344782806311145 0.9724957615949829 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 5 30 -0.0344280856789903 0.9725357876093812 |
| Cellular senescence 4 41 -0.0341907724514522 0.9727250247574636 |
| Establishment of sister chromatid cohesion 6 7 0.0341366763167248 0.972768162046749 |
| Sumoylation of dna replication proteins 15 36 -0.0341141596795313 0.9727861172660592 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 9 25 -0.0338363544082253 0.9730076459080684 |
| Nuclear envelope breakdown 12 40 -0.0334592535142013 0.9733083586096448 |
| Potential therapeutics for sars 6 38 -0.0328232063042515 0.9738155722265752 |
| Transcriptional regulation by small rnas 11 37 -0.0323808333954446 0.974168347207129 |
| Sumoylation of rna binding proteins 18 34 -0.0323225396146648 0.9742148345808532 |
| Processing of dna double strand break ends 3 27 0.0322511621234208 0.9742717559028078 |
| Interactions of rev with host cellular proteins 18 34 -0.0321282723989619 0.9743697569301693 |
| Interactions of vpr with host cellular proteins 11 33 -0.0319118645589444 0.9745423369097246 |
| Extracellular matrix organization 6 30 -0.0318579967394146 0.9745852953688624 |
| Cytosolic iron sulfur cluster assembly 6 7 0.0317891668245192 0.9746401858933048 |
| Hiv elongation arrest and recovery 3 19 -0.0317434007502297 0.9746766835179216 |
| Response to elevated platelet cytosolic ca2 11 33 -0.0311524070811359 0.9751479951208633 |
| Eph ephrin signaling 9 32 -0.0309755062566602 0.9752890734727516 |
| Ns1 mediated effects on host pathways 13 34 -0.0307535671695093 0.975466070917764 |
| G2 m dna damage checkpoint 13 34 -0.0306616079101643 0.9755394092054532 |
| Viral messenger rna synthesis 11 34 -0.0305411927891104 0.9756354415962832 |
| Hcmv late events 11 34 -0.0304933292600525 0.9756736133882448 |
| Nuclear import of rev protein 17 31 -0.0304610693101219 0.9756993411527092 |
| Microrna mirna biogenesis 1 11 -0.0302519938146294 0.9758660824169768 |
| Prolactin receptor signaling 0 3 0.0302509220869225 0.9758669371407772 |
| Signaling by hedgehog 8 56 0.0302260837054706 0.9758867462433868 |
| Rhobtb gtpase cycle 2 30 -0.0302020937165635 0.9759058787502076 |
| Translation of sars cov 2 structural proteins 6 18 -0.0301175618556026 0.9759732947486616 |
| Postmitotic nuclear pore complex npc reformation 10 23 -0.030104123762714 0.9759840119359648 |
| Phase ii conjugation of compounds 12 28 -0.0300613253611808 0.9760181446717217 |
| Estrogen dependent gene expression 5 29 -0.0295362480619903 0.9764369097709464 |
| Signaling by ntrks 5 31 -0.0290789061534622 0.9768016591341206 |
| Rab regulation of trafficking 3 31 -0.0290737812011684 0.9768057465262558 |
| Cohesin loading onto chromatin 7 8 0.028985255452264 0.9768763500989768 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 12 22 -0.028899420113837 0.9769448081120202 |
| Cargo trafficking to the periciliary membrane 4 19 0.0281099999956672 0.9775744183829936 |
| Export of viral ribonucleoproteins from nucleus 10 29 -0.0280827502323298 0.9775961519684376 |
| Sumoylation of sumoylation proteins 11 28 -0.0278802909631066 0.9777576278658632 |
| Fcgr activation 0 2 0.0276942185742019 0.9779060348460328 |
| Neddylation 26 81 0.0276601862244292 0.977933178334162 |
| Sumoylation of ubiquitinylation proteins 10 28 -0.0276396934327654 0.9779495229671512 |
| Pre notch processing in the endoplasmic reticulum 1 2 0.027510359457792 0.9780526773230795 |
| Regulation of glucokinase by glucokinase regulatory protein 10 27 -0.0272011247865401 0.97829931858934 |
| Dna damage bypass 6 25 -0.0268825694170312 0.9785533960838286 |
| Regulation of mrna stability by proteins that bind au rich elements 9 63 0.0266408651271658 0.9787461791575534 |
| Signaling by kit in disease 0 5 0.0261546800115342 0.9791339636153238 |
| Ephb mediated forward signaling 5 15 -0.0260557102629589 0.9792129031471792 |
| Phospholipid metabolism 10 49 0.0256105732024019 0.9795679526411858 |
| Signaling by robo receptors 18 136 0.0254100635593314 0.97972788414113 |
| Rhoh gtpase cycle 5 22 0.0253878665054428 0.9797455891159964 |
| G1 s specific transcription 1 10 0.0252508067408375 0.979854911938654 |
| Hiv transcription initiation 0 14 0.0252386767018333 0.9798645872259906 |
| Rab gefs exchange gtp for gdp on rabs 2 22 -0.0249837453363573 0.980067928905032 |
| Signaling by erythropoietin 1 4 -0.0241618015963873 0.9807235471385772 |
| Retrograde neurotrophin signalling 8 8 -0.0239804756311428 0.9808681824181836 |
| Ca dependent events 2 7 0.0236755734698004 0.981111390090943 |
| Antigen presentation folding assembly and peptide loading of class i mhc 4 16 0.0235205096750446 0.9812350786547246 |
| Transcriptional regulation by ventx 2 16 -0.0228380387122375 0.981779465425215 |
| Mecp2 regulates transcription of neuronal ligands 3 3 -0.0223812884352565 0.9821438062793368 |
| Processive synthesis on the c strand of the telomere 2 12 -0.0222440116267489 0.9822533100634548 |
| Cell death signalling via nrage nrif and nade 4 12 -0.0220145909178893 0.9824363164894244 |
| Transcriptional regulation by runx1 12 72 0.0205569113764452 0.983599112935608 |
| Cell cell junction organization 0 9 0.019938839821382 0.9840921615994838 |
| Cargo concentration in the er 8 15 0.0189010125068148 0.9849200718223344 |
| Signaling by notch 10 61 0.018626036470009 0.9851394323374908 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 10 11 0.0185883278080811 0.9851695142886036 |
| Rho gtpases activate rocks 2 10 0.0158123669617259 0.987384082261994 |
| Downregulation of erbb2 signaling 2 7 0.0150002053063812 0.9880320165905117 |
| Notch3 intracellular domain regulates transcription 3 3 -0.0150000835864087 0.988032113698073 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 11 12 0.0147621962801389 0.9882218992914948 |
| Signaling by braf and raf1 fusions 3 23 0.014145213409306 0.9887141289721716 |
| Downstream signaling of activated fgfr1 1 3 -0.0134298229217377 0.9892848737343494 |
| Downstream signaling of activated fgfr2 1 3 -0.0134298229217377 0.9892848737343494 |
| Downstream signaling of activated fgfr3 1 3 -0.0134298229217377 0.9892848737343494 |
| Downstream signaling of activated fgfr4 1 3 -0.0134298229217377 0.9892848737343494 |
| Glutathione synthesis and recycling 5 6 0.0121102036394413 0.9903376916627324 |
| Rab geranylgeranylation 4 19 0.0109377622227867 0.9912731023995982 |
| Synthesis of diphthamide eef2 1 4 -0.0106925136992486 0.991468770965861 |
| Gap filling dna repair synthesis and ligation in gg ner 4 19 0.0105546362170361 0.9915787750723876 |
| Translesion synthesis by polh 0 13 0.0095800401217562 0.9923563508139044 |
| Deposition of new cenpa containing nucleosomes at the centromere 0 8 0.0057893435028528 0.9953807980051496 |
| Dcc mediated attractive signaling 2 2 -0.0052435754456458 0.9958162512806096 |
| Inositol phosphate metabolism 2 8 0.0040882959044618 0.996738020904714 |
| Beta catenin independent wnt signaling 10 57 0.0023821594189222 0.9980993135759032 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 1 2 -0.0017614018279066 0.998594605402858 |
| Intra golgi traffic 6 14 0.0008250654954839 0.9993416930541908 |
| Rhoj gtpase cycle 5 24 0.0 1.0 |
| Vesicle mediated transport 59 236 0.0 1.0 |
| Clathrin mediated endocytosis 23 56 0.0 1.0 |
| Costimulation by the cd28 family 8 14 0.0 1.0 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 1 23 0.0 1.0 |
| Recognition of dna damage by pcna containing replication complex 3 19 0.0 1.0 |
| Maturation of sars cov 2 spike protein 5 12 0.0 1.0 |
| Deadenylation of mrna 4 15 0.0 1.0 |
| Cell junction organization 3 19 0.0 1.0 |
| Polymerase switching on the c strand of the telomere 3 15 0.0 1.0 |
| Membrane trafficking 58 230 0.0 1.0 |
| Termination of translesion dna synthesis 0 19 0.0 1.0 |
| Unfolded protein response upr 7 43 0.0 1.0 |
| Diseases of mitotic cell cycle 1 17 0.0 1.0 |
| Rho gtpases activate formins 13 58 0.0 1.0 |
| Organelle biogenesis and maintenance 23 89 0.0 1.0 |
| Innate immune system 69 278 0.0 1.0 |
| Flt3 signaling in disease 2 6 0.0 1.0 |
| Synthesis of pyrophosphates in the cytosol 1 2 0.0 1.0 |
| Pcna dependent long patch base excision repair 3 19 0.0 1.0 |
| Interferon gamma signaling 1 14 0.0 1.0 |
| Vegfr2 mediated vascular permeability 9 10 0.0 1.0 |
| Regulated necrosis 6 15 0.0 1.0 |
| Extension of telomeres 7 33 0.0 1.0 |
| Interaction between l1 and ankyrins 1 3 0.0 1.0 |
| Tbc rabgaps 5 13 0.0 1.0 |
| Signal transduction by l1 4 11 0.0 1.0 |
| Signaling by rho gtpases miro gtpases and rhobtb3 66 247 0.0 1.0 |
| Trans golgi network vesicle budding 16 33 0.0 1.0 |
| Rhot1 gtpase cycle 1 2 0.0 1.0 |
| Protein ubiquitination 8 25 0.0 1.0 |
| Cilium assembly 13 55 0.0 1.0 |
| Slc transporter disorders 13 34 0.0 1.0 |
| Disorders of transmembrane transporters 23 78 0.0 1.0 |
| Signaling by alk in cancer 14 34 0.0 1.0 |
| Type i hemidesmosome assembly 2 2 0.0 1.0 |
| Nuclear events stimulated by alk signaling in cancer 4 11 0.0 1.0 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 2 25 0.0 1.0 |
| Signaling by wnt 10 90 0.0 1.0 |
| Golgi to er retrograde transport 12 70 0.0 1.0 |
| Er to golgi anterograde transport 23 79 0.0 1.0 |
| Telomere c strand lagging strand synthesis 5 22 0.0 1.0 |
| Lagging strand synthesis 4 20 0.0 1.0 |
| Recruitment of numa to mitotic centrosomes 9 32 0.0 1.0 |
| Apoptotic execution phase 2 29 0.0 1.0 |
| Resolution of abasic sites ap sites 2 29 0.0 1.0 |
| Dna repair 29 116 0.0 1.0 |
| Oncogenic mapk signaling 5 28 0.0 1.0 |
| Hdms demethylate histones 5 9 0.0 1.0 |
| Base excision repair 2 30 0.0 1.0 |
| Translocation of slc2a4 glut4 to the plasma membrane 7 31 0.0 1.0 |
| Reproduction 2 23 0.0 1.0 |
| Regulation of tp53 activity through phosphorylation 8 33 0.0 1.0 |
| Intracellular signaling by second messengers 11 85 0.0 1.0 |
| Autophagy 17 45 0.0 1.0 |
| Resolution of sister chromatid cohesion 26 59 0.0 1.0 |
| Nuclear envelope ne reassembly 8 44 0.0 1.0 |
| Complex i biogenesis 4 30 0.0 1.0 |
| Tryptophan catabolism 1 2 0.0 1.0 |
| Pten regulation 11 65 0.0 1.0 |
| Copi mediated anterograde transport 18 56 0.0 1.0 |
| Copi dependent golgi to er retrograde traffic 2 46 0.0 1.0 |
| Mitotic spindle checkpoint 27 57 0.0 1.0 |
| Transport to the golgi and subsequent modification 24 81 0.0 1.0 |
| Acyl chain remodelling of pg 2 2 0.0 1.0 |
| Intra golgi and retrograde golgi to er traffic 20 87 0.0 1.0 |
| Phosphorylation of the apc c 6 13 0.0 1.0 |
| Cell cycle mitotic 81 251 0.0 1.0 |
| Meiosis 2 23 0.0 1.0 |
| Cell cell communication 2 28 0.0 1.0 |
| Mitotic prometaphase 42 88 0.0 1.0 |
| Polymerase switching 0 14 0.0 1.0 |
| Senescence associated secretory phenotype sasp 2 22 0.0 1.0 |
| Tcf dependent signaling in response to wnt 8 63 0.0 1.0 |
| Tp53 regulates transcription of dna repair genes 11 28 0.0 1.0 |
| Regulation of hsf1 mediated heat shock response 11 52 0.0 1.0 |
| Cellular responses to stimuli 66 328 0.0 1.0 |
| Mapk family signaling cascades 12 89 0.0 1.0 |
| Cs ds degradation 1 2 0.0 1.0 |
| Dna strand elongation 9 30 0.0 1.0 |
| L1cam interactions 13 39 0.0 1.0 |
| Dna double strand break repair 12 57 0.0 1.0 |
| Regulation of cholesterol biosynthesis by srebp srebf 6 27 0.0 1.0 |
| Homology directed repair 8 41 0.0 1.0 |
| Nonhomologous end joining nhej 17 18 0.0 1.0 |
| Cell cycle 89 298 0.0 1.0 |
| Dna damage recognition in gg ner 7 18 0.0 1.0 |
| Formation of incision complex in gg ner 3 17 0.0 1.0 |
| Nucleotide excision repair 17 56 0.0 1.0 |
| Nuclear pore complex npc disassembly 10 30 0.0 1.0 |
| Leishmania infection 8 37 0.0 1.0 |
| Dual incision in gg ner 4 24 0.0 1.0 |
| Post translational protein modification 108 418 0.0 1.0 |
| Formation of tc ner pre incision complex 12 25 0.0 1.0 |
| Transcription coupled nucleotide excision repair tc ner 15 45 0.0 1.0 |
| Dual incision in tc ner 4 33 0.0 1.0 |
| Copii mediated vesicle transport 7 32 0.0 1.0 |
| Hsf1 dependent transactivation 3 15 0.0 1.0 |
| Srp dependent cotranslational protein targeting to membrane 13 91 0.0 1.0 |
| Host interactions of hiv factors 11 94 0.0 1.0 |
| Cytokine signaling in immune system 46 178 0.0 1.0 |
| Adaptive immune system 41 191 0.0 1.0 |
| Cellular response to heat stress 18 61 0.0 1.0 |
| Dissolution of fibrin clot 2 2 0.0 1.0 |
| Global genome nucleotide excision repair gg ner 15 43 0.0 1.0 |
| Cell surface interactions at the vascular wall 3 17 0.0 1.0 |
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