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Term es nes pval sidak fdr geneset_size leading_edge
Mrna splicing -0.4081509718500486 -2.6997553069744025 0.0069390491512053565 0.9999412116937006 1.0 140 O94906,Q9Y4Z0,Q96DI7,Q15029,Q15366,O43143,Q96I25,Q9UMS4,Q10570,P16383,Q9BWJ5,Q15365,P62304,Q9Y3B4,P41223,Q9Y333,P62318,P62316,P14866,Q16629,P84103,Q9UK45,Q9Y5S9,Q8IYB3,P55769,Q09161,Q15393,P62312,P38919,Q00839,P17844,Q8IWX8,Q07955,P26368,Q86U42,Q8IWZ8,O43447,Q9Y3C6,P09234,P19387
Defects in biotin btn metabolism -0.9009198962758325 -2.5284020315471607 0.011458305993141682 0.9999999004610701 1.0 7 Q96RQ3,Q13085,P05165,P11498
Heme degradation 0.9291441204357478 2.3137138343535173 0.020683424524365446 0.9999999999997998 1.0 4 P09601
Biotin transport and metabolism -0.8502489322964961 -2.275926460504289 0.022850411473358978 0.999999999999991 1.0 9 P05165,Q96RQ3,P11498,Q13085,O00763
Thrombin signalling through proteinase activated receptors pars -0.8295439134684884 -2.2507336013098413 0.024402415225854845 0.999999999999999 1.0 6 P62873,P62879
Glyoxylate metabolism and glycine degradation -0.8324137382052156 -2.161358444595088 0.030667661495919152 1.0 1.0 11 P36957,P00505,Q02218,P30038,P10515,P08559,P21953,P23378,P09622
Gaba b receptor activation -0.8077049511607615 -2.1574219819786746 0.030972799989747557 1.0 1.0 6 P62873,P62879,P08754,P04899
Adp signalling through p2y purinoceptor 12 -0.8077049511607615 -2.1574219819786746 0.030972799989747557 1.0 1.0 6 P62873,P62879,P08754,P04899
G alpha z signalling events -0.8077049511607615 -2.1574219819786746 0.030972799989747557 1.0 1.0 6 P62873,P62879,P08754,P04899
Scavenging by class b receptors 0.9975617189881134 2.1378490834147867 0.03252899383863306 1.0 1.0 1
Constitutive signaling by aberrant pi3k in cancer -0.802722918309086 -2.1360051224299252 0.0326789962960945 1.0 1.0 6 Q9NWH9
Glucagon signaling in metabolic regulation -0.8010038685851197 -2.128604116661338 0.033287027638909006 1.0 1.0 6 P62873,P62879
Vasopressin regulates renal water homeostasis via aquaporins -0.8010038685851197 -2.128604116661338 0.033287027638909006 1.0 1.0 6 P62873,P62879
Met receptor activation -0.9975617189880794 -2.1220389544596814 0.03383446696858039 1.0 1.0 1 Q9NWH9
Hydrolysis of lpc 0.9914660164583968 2.1072215150087397 0.035098382819270135 1.0 1.0 1
Signaling by tgf beta receptor complex in cancer -0.9923803718378209 -2.0958589061645183 0.036094709020776605 1.0 1.0 1 P62942
Lysine catabolism -0.7929749953918017 -2.0939623239168728 0.0362633366052294 1.0 1.0 6 P36957,Q02218,Q92947,P49419,P09622
Synthesis of lipoxins lx 0.9862846693081377 2.0811543499885383 0.037419780436778405 1.0 1.0 1
Sensory perception of taste -0.9881133800670198 -2.074273350842035 0.0380539313211512 1.0 1.0 1 P62873
Olfactory signaling pathway -0.9881133800670198 -2.074273350842035 0.0380539313211512 1.0 1.0 1 P62873
Activation of the phototransduction cascade -0.9881133800670198 -2.074273350842035 0.0380539313211512 1.0 1.0 1 P62873
Pyrimidine catabolism -0.9804937519048749 -2.035672371925008 0.04178326516029385 1.0 1.0 1 Q9H0P0
Runx1 regulates estrogen receptor mediated transcription 0.9762267601341055 2.0304694234199157 0.04230884615549657 1.0 1.0 1
Triglyceride biosynthesis 0.9762267601341055 2.0304694234199157 0.04230884615549657 1.0 1.0 1
Defects in vitamin and cofactor metabolism -0.8007397280208897 -2.023368653594719 0.04303515350131182 1.0 1.0 11 Q96RQ3,Q13085,P05165,P11498
Gaba receptor activation -0.7813090014517445 -2.020731225210627 0.043307595621430384 1.0 1.0 7 P62873,P62879,P08754,P04899
Regulation of gene expression by hypoxia inducible factor 0.9716549832368181 2.0073961421642528 0.04470749927824169 1.0 1.0 1
Thromboxane signalling through tp receptor -0.8105540887912891 -1.9890427765577299 0.04669648161150408 1.0 1.0 5 P62873,P62879
Acetylcholine regulates insulin secretion -0.9710454129838152 -1.9877133356535446 0.046843403191924704 1.0 1.0 1 P29966
Urea cycle 0.9676927765925023 1.9873827527506296 0.04687999749283733 1.0 1.0 1
Phosphate bond hydrolysis by nudt proteins -0.8524246567764417 -1.9856175192109666 0.047075809668521096 1.0 1.0 4 Q96DE0,P36639
G beta gamma signalling through cdc42 -0.8086053981576389 -1.9808482145715176 0.04760829796587318 1.0 1.0 5 P62873,P62879
Regulation of pyruvate dehydrogenase pdh complex -0.7699512393087153 -1.9711045550952047 0.048711917830913 1.0 1.0 7 P08559,P10515,P09622,Q8NCN5
Small interfering rna sirna biogenesis -0.8474945768964698 -1.9656237215828076 0.049342091863715964 1.0 1.0 4 Q99598
G beta gamma signalling through pi3kgamma -0.8014189110343685 -1.9505719059943154 0.05110799190305437 1.0 1.0 5 P62879,P62873,P61586
Ldl remodeling -0.9628162145686987 -1.9458633780661863 0.05167115306101189 1.0 1.0 1 P07237
Vldl assembly -0.9628162145686987 -1.9458633780661863 0.05167115306101189 1.0 1.0 1 P07237
Tnfr1 mediated ceramide production -0.9625114294422129 -1.944312037782618 0.051857833890801786 1.0 1.0 1 P63244
Mecp2 regulates neuronal receptors and channels -0.7614680293300488 -1.9338864682304582 0.05312708822593715 1.0 1.0 7 Q9NWH9,P18031,Q92769
Dermatan sulfate biosynthesis 0.9570252971654982 1.9334292409736382 0.05318334198512553 1.0 1.0 1
Defective chst14 causes eds musculocontractural type 0.9570252971654982 1.9334292409736382 0.05318334198512553 1.0 1.0 1
G protein beta gamma signalling -0.7591161410557266 -1.9235455530667418 0.054411571368413014 1.0 1.0 7 P62873,P62879,P61586
G alpha s signalling events -0.7623893150045313 -1.9157738360248686 0.05539388941844581 1.0 1.0 8 P62873,P62879,P08754,P04899
Signaling by fgfr2 iiia tm -0.760143378995451 -1.905871676080704 0.05666685666003479 1.0 1.0 8 Q09161,P19387
Fgfr2 mutant receptor activation -0.760143378995451 -1.905871676080704 0.05666685666003479 1.0 1.0 8 Q09161,P19387
Passive transport by aquaporins 0.9515391648887532 1.9056444230587253 0.05669635446380994 1.0 1.0 1
Collagen degradation 0.9497104541298382 1.8963776422095813 0.05791012611710222 1.0 1.0 1
Adrenaline noradrenaline inhibits insulin secretion -0.7883893514263804 -1.895457749202519 0.058031784156214794 1.0 1.0 5 P62879,P62873,P04899
Propionyl coa catabolism -0.9254614967117362 -1.8920198929902998 0.05848833036623091 1.0 1.0 3 P05165
Arachidonic acid metabolism 0.7535942472900223 1.8871720744752603 0.059137185038287576 1.0 1.0 7 Q9H7Z7,Q14914
Abacavir transmembrane transport 0.9478817433709233 1.8871083952461245 0.059145747758752254 1.0 1.0 1
Slbp dependent processing of replication dependent histone pre mrnas -0.9226765983067285 -1.8815059270417724 0.05990312977772039 1.0 1.0 3 Q09161,P62318
Androgen biosynthesis 0.9457482474855223 1.8762912566863992 0.060615296973615784 1.0 1.0 1
Adp signalling through p2y purinoceptor 1 -0.824814991519919 -1.8731544576694346 0.061047059150533656 1.0 1.0 4 P62879,P62873
Sema4d mediated inhibition of cell attachment and migration -0.9194211100404233 -1.869203568145347 0.06159449804848083 1.0 1.0 3 Q9NWH9,P61586
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.8138508229476967 1.854357147258534 0.06368808128483083 1.0 1.0 4 P11802
Signal amplification -0.7525683889376159 -1.8508967406114172 0.06418440975877493 1.0 1.0 9 P62873,P62879,P08754,P04899
Sulfide oxidation to sulfate 0.9381286193233768 1.837633907362909 0.06611636889614192 1.0 1.0 1
Metabolism of lipids 0.4061455807909056 1.8289035916724115 0.06741405209742446 1.0 1.0 197 Q16836,Q15067,Q15436,O43772,Q4G176,Q6ZMG9,Q06136,Q9NQZ5,Q8NCC3,Q96N66,O75182,P35790,P68400,O95772,Q14914,Q9H7Z7,Q53GQ0,Q9BWD1,Q8IV08,P04062,P16278,Q8N8N7,O95470,Q96G23,Q13510,Q14739,Q6UWP7,Q6IAN0,P51659,P06865,Q96PE3,P51648,Q15392,P35610,Q9UMR5,P27544,Q9HCL2,Q15800,P50897,Q15648,Q14534,Q9UKG9,Q9Y3C7,Q9NZJ7,O14975,Q9BY49,Q8N2A8,Q9NPH0,Q9UBM7,Q16850,O15254
Regulation of fzd by ubiquitination -0.9390429747028066 -1.824602388177423 0.06806105278086472 1.0 1.0 1 P40818
Metabolism of fat soluble vitamins -0.8114703937858296 -1.8183780344457667 0.06900637325089942 1.0 1.0 4 P01130
Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis -0.9375190490703776 -1.8168133693284256 0.06924569500837885 1.0 1.0 1 O75376
Dna methylation -0.809715384258382 -1.8111544813064007 0.07011694203761354 1.0 1.0 4 Q96T88,P84243
Transport of nucleotide sugars 0.9326424870466319 1.8097791112152224 0.07033004851780733 1.0 1.0 1
Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0.9308137762877169 1.8004906347794998 0.07178320104101177 1.0 1.0 1
Sphingolipid de novo biosynthesis 0.7513771124244514 1.790930129782794 0.07330450796006671 1.0 1.0 11 Q06136,P27544,Q6ZMG9,O95470,Q96G23
Ca2 pathway -0.7236509499568748 -1.7899153249805928 0.07346752480367913 1.0 1.0 6 P62879,P62873
Chrebp activates metabolic gene expression -0.7625388889806461 -1.7852983542008392 0.0742129356847514 1.0 1.0 5 Q13085,O00763
Pi3k akt activation -0.9311185614141759 -1.784081920150984 0.07441035466763646 1.0 1.0 1 P61586
Rho gtpases activate rhotekin and rhophilins -0.9311185614141759 -1.784081920150984 0.07441035466763646 1.0 1.0 1 P61586
Met activates rap1 and rac1 -0.7602516580716833 -1.7755014902276844 0.07581511971099464 1.0 1.0 5 Q9NWH9,P46109
Class b 2 secretin family receptors -0.8005608522282535 -1.7734024493120206 0.0761620434411161 1.0 1.0 4 P62873,P62879
Detoxification of reactive oxygen species -0.7351411114678815 -1.7733320974608953 0.07617369339242996 1.0 1.0 9 P04179,P32119,P07237,P30044,P30048
Nucleotide catabolism -0.7393779623817978 -1.771320436547374 0.07650743090550205 1.0 1.0 10 Q96DE0,Q9H0P0,P36639
Metabolism of porphyrins 0.731921520854088 1.767737045114641 0.07710487383505638 1.0 1.0 8 P09601
Surfactant metabolism 0.9228893629990855 1.7602229325932808 0.07837001516155784 1.0 1.0 1
Met receptor recycling -0.7539218085178618 -1.748348233043087 0.0804037459820488 1.0 1.0 5 Q9NWH9,P46109
Activation of kainate receptors upon glutamate binding -0.7517313616073037 -1.7389381161379058 0.08204564874733045 1.0 1.0 5 P62879,P62873
Purine catabolism -0.7224322365875865 -1.7383704028174563 0.0821455683541954 1.0 1.0 8 Q96DE0,P36639
Met promotes cell motility -0.711417116321366 -1.735404893258737 0.08266911398427323 1.0 1.0 6 Q9NWH9,P46109
Adora2b mediated anti inflammatory cytokines production -0.7299934850453523 -1.7293039290716894 0.08375471381106547 1.0 1.0 10 P62873,P62879,P08754,P04899
Glucagon like peptide 1 glp1 regulates insulin secretion -0.7147043801666835 -1.7265327111979671 0.08425161967043238 1.0 1.0 7 P62873,P62879
Activation of puma and translocation to mitochondria -0.9186223712282583 -1.7201069512651326 0.0854130024159474 1.0 1.0 1 P04637
Runx3 regulates cdkn1a transcription -0.9186223712282583 -1.7201069512651326 0.0854130024159474 1.0 1.0 1 P04637
Activation of noxa and translocation to mitochondria -0.9186223712282583 -1.7201069512651326 0.0854130024159474 1.0 1.0 1 P04637
Tp53 regulates transcription of genes involved in cytochrome c release -0.9186223712282583 -1.7201069512651326 0.0854130024159474 1.0 1.0 1 P04637
Glutamate and glutamine metabolism -0.7168737227089457 -1.7134957140291995 0.08662138118243146 1.0 1.0 8 P32322,P00505,P04181,P00367,O94925,P15104,P54886
Regulation of pten mrna translation 0.9131362389515392 1.710631944407069 0.08714907810850248 1.0 1.0 1
Competing endogenous rnas cernas regulate pten translation 0.9131362389515392 1.710631944407069 0.08714907810850248 1.0 1.0 1
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 -0.784219800247694 -1.705721780658494 0.0880598924201963 1.0 1.0 4 P84243
Prolonged erk activation events -0.7438819629465967 -1.7051607014108678 0.08816445710946974 1.0 1.0 5 Q02750,P46109
Foxo mediated transcription of oxidative stress metabolic and neuronal genes -0.7822073009051242 -1.6973614803723678 0.0896283403528293 1.0 1.0 4 Q92769,P04179
Tgf beta receptor signaling in emt epithelial to mesenchymal transition -0.8737179693130425 -1.6952262549384494 0.090032508125653 1.0 1.0 3 P62942,P61586
O linked glycosylation of mucins 0.739259830951785 1.692794048766793 0.09049467587774007 1.0 1.0 5 Q8N4A0
O linked glycosylation 0.739259830951785 1.692794048766793 0.09049467587774007 1.0 1.0 5 Q8N4A0
Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway -0.913136238951514 -1.69199672907716 0.09064659728583235 1.0 1.0 1 Q12933
Pink1 prkn mediated mitophagy 0.7240255657693898 1.6883627036709055 0.09134162531354328 1.0 1.0 10 P21796,Q9NS69
Nicotinate metabolism 0.7732061064075855 1.687919354566679 0.09142671076823383 1.0 1.0 4 P43490
Regulation of foxo transcriptional activity by acetylation 0.9085644620542518 1.6873784376449927 0.09153060724361306 1.0 1.0 1
Processing of capped intron containing pre mrna -0.377989831650761 -1.6760615662966805 0.09372613394412088 1.0 1.0 180 O94906,Q9BW27,Q9Y4Z0,Q96DI7,Q9UBU9,Q9NRG9,Q15029,Q15366,O43143,Q96I25,Q9UMS4,Q10570,P16383,Q9BWJ5,Q15365,P83876,P62304,Q9Y3B4,P78406,O00148,O43172,P37198,P41223,O75934,O95400,P08621,Q15007,Q9Y333,P62318,P62316,Q08211,P14866,Q16629,P55735,P84103,Q9UK45,Q9UKX7,Q9Y5S9,Q8IYB3,P55769,Q09161,Q15393,P62312,Q7RTV0,Q8WWY3,P38919,P52948,Q00839,P17844,Q9P2I0,Q9BVL2,Q8IWX8,Q07955,Q13838,P26368,Q86U42,Q05519,O75694,Q8IWZ8,Q8NFH5,O94992,P06730,P09651,Q13769,O43447,Q96J01,Q9Y3C6,P09234,P19387
Norepinephrine neurotransmitter release cycle 0.9049070405364219 1.668773635235947 0.09516224960210407 1.0 1.0 1
Acetylcholine neurotransmitter release cycle 0.9049070405364219 1.668773635235947 0.09516224960210407 1.0 1.0 1
Receptor type tyrosine protein phosphatases 0.9049070405364219 1.668773635235947 0.09516224960210407 1.0 1.0 1
Serotonin neurotransmitter release cycle 0.9049070405364219 1.668773635235947 0.09516224960210407 1.0 1.0 1
Hs gag biosynthesis 0.902773544651021 1.6579203995694392 0.09733353408903911 1.0 1.0 1
Regulated proteolysis of p75ntr -0.9061261810423407 -1.6560628925803036 0.09770908302317016 1.0 1.0 1 Q92542
Signaling by retinoic acid -0.7082183066301975 -1.6526276051727677 0.09840667632556843 1.0 1.0 9 P08559,P50416,P10515,P09622
Gaba synthesis release reuptake and degradation -0.8616018691964474 -1.6487382545328881 0.09920126942503549 1.0 1.0 3 P80404,P51649
Synthesis of pips at the er membrane -0.8605339350291394 -1.6446340669844193 0.10004529709413656 1.0 1.0 3 Q13614
The nlrp3 inflammasome 0.761582448137868 1.6399689094570231 0.10101163152681902 1.0 1.0 4
Inflammasomes 0.7615824481378681 1.6399689094570231 0.10101163152681902 1.0 1.0 4
Purinergic signaling in leishmaniasis infection 0.7615824481378681 1.6399689094570231 0.10101163152681902 1.0 1.0 4
Negative regulation of met activity -0.6952235833228604 -1.6391621410970052 0.1011794961308321 1.0 1.0 7 P40818,P18031,Q9NWH9
G2 phase 0.8988113380067053 1.637764274538466 0.1014708767579251 1.0 1.0 1
Diseases associated with n glycosylation of proteins 0.6974497990505766 1.6358392366262118 0.10187323782177593 1.0 1.0 7 Q9BV10
Glucagon type ligand receptors -0.8576404339095117 -1.6335087894547893 0.10236203366731056 1.0 1.0 3 P62879,P62873
Presynaptic function of kainate receptors -0.8576404339095117 -1.6335087894547893 0.10236203366731056 1.0 1.0 3 P62879,P62873
Prostacyclin signalling through prostacyclin receptor -0.8576404339095117 -1.6335087894547893 0.10236203366731056 1.0 1.0 3 P62879,P62873
G protein activation -0.8576404339095117 -1.6335087894547893 0.10236203366731056 1.0 1.0 3 P62879,P62873
Potassium channels -0.8576404339095117 -1.6335087894547893 0.10236203366731056 1.0 1.0 3 P62873,P62879
Inwardly rectifying k channels -0.8576404339095117 -1.6335087894547893 0.10236203366731056 1.0 1.0 3 P62879,P62873
Glycogen breakdown glycogenolysis 0.6913919413919423 1.6327220113261778 0.10252747588947653 1.0 1.0 6 P35573,P06737,Q93100,P11216,P10253
Bmal1 clock npas2 activates circadian gene expression 0.8478821302397826 1.6134214512128822 0.10665297582337496 1.0 1.0 3 P43490
Rrna modification in the mitochondrion 0.890582139591588 1.5959057321847385 0.1105098415535073 1.0 1.0 1
Aquaporin mediated transport -0.6840868996010385 -1.588989275403369 0.11206281398965423 1.0 1.0 7 P62873,P62879
Synthesis of udp n acetyl glucosamine -0.7152390581977839 -1.5812048087864181 0.11383121621021841 1.0 1.0 5 Q96EK6,Q9UJ70
Synthesis of pg 0.7459900902678032 1.5754365806819968 0.11515570630674166 1.0 1.0 4 Q8N2A8
Signaling by fgfr2 in disease -0.6955630894908527 -1.574160823972837 0.11545027376884587 1.0 1.0 10 Q09161,P19387
Attachment and entry -0.8893629990856219 -1.5700989286189309 0.11639209781032189 1.0 1.0 1 P55072
Lgi adam interactions -0.8854007924413065 -1.5497800991380044 0.12119430516507856 1.0 1.0 1 Q15334
Met activates ras signaling -0.7464409698451533 -1.5479450564546646 0.12163552543193701 1.0 1.0 4 Q9NWH9
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.703642946802677 1.5388136154875407 0.12384980493855258 1.0 1.0 5 Q9Y6K9,P61088,Q15750
Er quality control compartment erqc 0.8282279939127799 1.5380845572211683 0.12402794133645956 1.0 1.0 3 Q9UKM7
Trafficking of myristoylated proteins to the cilium 0.8255796865486529 1.5279143371300334 0.12653380804049164 1.0 1.0 3
Mitochondrial iron sulfur cluster biogenesis -0.7411887226157137 -1.5258818618873922 0.127039288627403 1.0 1.0 4 Q86SX6,P22570
Erythropoietin activates phosphoinositide 3 kinase pi3k 0.8762572386467545 1.5230839866184014 0.1277376946037263 1.0 1.0 1
Erythropoietin activates stat5 0.8762572386467545 1.5230839866184014 0.1277376946037263 1.0 1.0 1
Dectin 2 family 0.8762572386467545 1.5230839866184014 0.1277376946037263 1.0 1.0 1
Cd22 mediated bcr regulation 0.8762572386467545 1.5230839866184014 0.1277376946037263 1.0 1.0 1
2 ltr circle formation -0.740252017347752 -1.521944107627791 0.12802308601017431 1.0 1.0 4 O75531
Met activates ptpn11 -0.8280508443413007 -1.5193353544514319 0.1286781049163792 1.0 1.0 3 Q9NWH9
Acyl chain remodelling of pi 0.8750380981408112 1.5168905814256286 0.12929431197807806 1.0 1.0 1
Effects of pip2 hydrolysis 0.8212869777371005 1.5114207326354212 0.13068129035938858 1.0 1.0 3 P52429,Q8NCG7
Transport of small molecules 0.35271552984427484 1.4990953728675813 0.1338488918261238 1.0 1.0 159 P49721,P09601,Q8WTV0,Q9C0H2,P63218,P21796,P30519,Q99797,Q70HW3,O43242,P28072,P08183,Q93050,Q15904,Q9UEY8,Q9HD20,P45880,P28070,P35610,P20618,Q5SW96,Q9UBX3,Q9Y487,P51665,P98194,Q8TB61,P28074,O00231,Q9H300,P60900,Q9BUN8
Extra nuclear estrogen signaling -0.6863078844456417 -1.4915471872515547 0.13581789209231654 1.0 1.0 12 P62873,P62879,P08754,P04899
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.8154925282098178 1.489141649267719 0.13645007233694795 1.0 1.0 3 Q9NVD7,Q15404
Endosomal vacuolar pathway 0.724733632452938 1.4871341639078035 0.1369793799647574 1.0 1.0 4 Q9UIQ6
Mrna editing -0.8716854617494457 -1.4794744798774155 0.13901354708842728 1.0 1.0 1 P55265
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane -0.7297123929748501 -1.4775796233193366 0.13952033171989786 1.0 1.0 4 P12235,P36404
Keratan sulfate keratin metabolism 0.657105808207959 1.4770299578610935 0.13966760704215142 1.0 1.0 6 O43505,P16278,P06865
Notch hlh transcription pathway -0.6905437069520314 -1.4735700245121128 0.14059739709102637 1.0 1.0 5 O75376,Q92769
Folding of actin by cct tric -0.6604847231010307 -1.458974187531387 0.14457221230574024 1.0 1.0 8 P50991,P40227,P78371,P48643,P17987,P49368,Q99832
Binding and uptake of ligands by scavenger receptors 0.6519314141689488 1.4534152353166898 0.14610849891395694 1.0 1.0 6
Integration of provirus -0.6853198573890719 -1.4507277644017278 0.14685568107381286 1.0 1.0 5 O75531
Inlb mediated entry of listeria monocytogenes into host cell -0.684782777119732 -1.4483780107181452 0.14751136109667917 1.0 1.0 5 Q9NWH9
Glycogen storage diseases 0.8030237523142666 1.441148432242271 0.1495427532841791 1.0 1.0 3 O43826
Downregulation of erbb4 signaling 0.8597988418165199 1.4395595314595362 0.1499920559226222 1.0 1.0 1
Rho gtpase cycle 0.34414369486588237 1.435055279165562 0.15127134583045354 1.0 1.0 154 O15498,Q13017,P07900,Q8TAA9,P02786,Q99707,Q9UQB8,P30519,Q93008,Q86Y07,P50402,P08670,Q9UJF2,Q9Y6M7,P46940,P28288,Q15904,Q9UEY8,Q68EM7,Q13505,P08238,Q8N6H7,O15173,P52565,Q14155,Q14739,Q8NBN3,Q96N67,P51648,Q96HY6,O14578,Q13190,Q6IAA8,P51572,Q16543,Q12792,Q7L576,P41440,O75976,O43396,P12814,Q658Y4,Q92974,Q96JJ3,Q13464,P61604,Q9BXS4,Q15642,Q9H2G2,O14964,Q9NSV4,Q86XL3,Q9HD26,O95202,Q07065,P38159,Q13618
Synthesis of prostaglandins pg and thromboxanes tx 0.7116148478422357 1.4324893330422581 0.15200382871343798 1.0 1.0 4 Q9H7Z7
Signaling by bmp -0.8616275525754145 -1.4279709351727115 0.15330022443999525 1.0 1.0 1 Q7Z3T8
Gastrin creb signalling pathway via pkc and mapk 0.7093518512422874 1.423054345727441 0.1547204016090622 1.0 1.0 4 Q15418
Creatine metabolism -0.8029772080624022 -1.4221105199047457 0.15499416930877885 1.0 1.0 3 P12532
Signaling by notch1 pest domain mutants in cancer -0.6462270446777433 -1.417444149381539 0.1563531124676456 1.0 1.0 7 O75376,Q92542,Q92769
Glycogen metabolism 0.6590490225926777 1.4144946983641895 0.15721670292018208 1.0 1.0 9 P35573,P06737,Q93100,Q16851,P11216,P10253
Prc2 methylates histones and dna -0.6766068804851697 -1.412581109565501 0.15777892661651505 1.0 1.0 5 P84243
Purine ribonucleoside monophosphate biosynthesis -0.6559115959608631 -1.394029818181722 0.16330860047142304 1.0 1.0 10 O15067,P20839,P22234,P22102,P12268
Mrna decay by 5 to 3 exoribonuclease -0.6509293927468762 -1.3930495738897513 0.1636048002223609 1.0 1.0 9 Q9UK45,Q9Y4Z0,P62312,Q6P2E9,Q9Y333,Q96F86
Reduction of cytosolic ca levels -0.7091200881279529 -1.3906321348332449 0.1643370066003289 1.0 1.0 4 P23634,P30626
Platelet calcium homeostasis -0.7091200881279529 -1.3906321348332449 0.1643370066003289 1.0 1.0 4 P23634,P30626
Rsk activation 0.7894690386081303 1.3889140170671324 0.16485889762922068 1.0 1.0 3 Q15418
Citric acid cycle tca cycle -0.6861090138717524 -1.3865084861847994 0.16559169081240155 1.0 1.0 18 P21912,P36957,O43837,P40926,P07954,P50213,Q96I99,Q02218,Q6P587,Q99798,O75390,P53597,P31040,P09622,Q9P2R7
Activation of bad and translocation to mitochondria -0.6433664773609785 -1.38112993749625 0.16723901212530334 1.0 1.0 8 P61981,Q04917,P27348,Q9Y3B8,P62258,P63104
Adenylate cyclase inhibitory pathway -0.7917047880451545 -1.378298362832366 0.16811118847153095 1.0 1.0 3 P63096,P08754,P04899
Synthesis of pa 0.6558084493597276 1.377368958739168 0.16839820491317137 1.0 1.0 10 Q8N2A8,Q9HCL2
Activation of bh3 only proteins -0.6565364980191741 -1.375947187379127 0.1688379845638388 1.0 1.0 11 P04637,P61981,P63167,Q04917,P27348,Q9Y3B8,P62258,P63104
Ethanol oxidation -0.7898749618786401 -1.3711820057616553 0.17031822611848968 1.0 1.0 3 P30837,P05091,P11766
Regulation of tp53 activity through methylation -0.630493136474416 -1.369974827282193 0.17069475967969439 1.0 1.0 6 O96017,Q9H9B1,P04637
Negative regulators of ddx58 ifih1 signaling -0.6406636651884617 -1.3688249973130402 0.17105398506049863 1.0 1.0 8 Q86UT6,Q15366,Q13526
Sumoylation of transcription cofactors -0.6675738651539805 -1.368191757522954 0.1712520609501087 1.0 1.0 14 Q15424,Q9UER7,Q99496,Q92841,P06748,Q9HC52,P17844,Q13263,P61956,Q13363,Q99497
Platelet homeostasis -0.6588619789876925 -1.3663924269148355 0.17181582449800104 1.0 1.0 12 P62873,P62879,P23634
Synthesis of pips at the late endosome membrane -0.701402397421835 -1.3579711601535263 0.1744728355323626 1.0 1.0 4 Q13496,Q13614
Regulation of localization of foxo transcription factors -0.62628022175702 -1.3507928500132809 0.17676179911176249 1.0 1.0 6 P27348,Q9Y3B8,P61981,P63104
Visual phototransduction -0.6364146692987992 -1.3494753407828393 0.17718433566327474 1.0 1.0 8 P62873,P01130
Activation of rac1 downstream of nmdars 0.7790337344849247 1.348674141847786 0.17744165467735984 1.0 1.0 3 Q14012
Synthesis of pc 0.6258125692594727 1.3338717706575265 0.1822458845521846 1.0 1.0 6 Q9NQZ5,P35790
Metabolism of cofactors 0.656128766338913 1.3316047084668488 0.18299011690566425 1.0 1.0 5 O75874,P00374,P07900
Beta oxidation of very long chain fatty acids 0.684933944836768 1.3211493059914126 0.1864515855100246 1.0 1.0 4 Q15067,P51659
Activated tak1 mediates p38 mapk activation 0.6842586943258128 1.3183298415766682 0.18739325546203522 1.0 1.0 4 Q9Y6K9,P61088,Q15750
Beta oxidation of pristanoyl coa 0.6839437150071725 1.317014662795731 0.1878337096803453 1.0 1.0 4 Q9UKG9,O15254
Tgf beta receptor signaling activates smads -0.6328856852545973 -1.310846295886134 0.1899096978511039 1.0 1.0 9 Q9Y3F4,P62136,P62942,P61081,Q9UNE7,P62140,Q9Y5K5
Heme biosynthesis -0.690077208770702 -1.309989502007406 0.19019938701778472 1.0 1.0 4 P36551,P06132
Insulin receptor recycling 0.6361830840812096 1.3096064338461082 0.19032901079503395 1.0 1.0 9 Q15904,Q93050
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0.7679170478804488 1.3057989546954583 0.19162093564483573 1.0 1.0 3 P61088,Q15750
Peptide ligand binding receptors 0.6240447126571818 1.301011680564382 0.19325445659648 1.0 1.0 7 Q9NZJ7,P42892
Class a 1 rhodopsin like receptors 0.6240447126571818 1.301011680564382 0.19325445659648 1.0 1.0 7 Q9NZJ7,P42892
Biosynthesis of specialized proresolving mediators spms 0.9765678251349676 1.299441779705575 0.19379236145008472 1.0 1.0 2
Synthesis of leukotrienes lt and eoxins ex 0.9765678251349676 1.299441779705575 0.19379236145008472 1.0 1.0 2
Formation of tubulin folding intermediates by cct tric -0.6379645653142382 -1.2912193043223192 0.19662764303201063 1.0 1.0 11 P50990,P50991,Q13885,P40227,P78371,P48643,P17987,P49368,Q99832,Q9BVA1
Iron uptake and transport 0.664642626255874 1.283304120956921 0.1993855494949397 1.0 1.0 17 P09601,P63208,Q86VP6,Q9Y487,Q93050,Q15904,P02786,P30519
Regulation of commissural axon pathfinding by slit and robo 0.8274916184090227 1.276494285204052 0.20178084569298704 1.0 1.0 1
Keratan sulfate degradation 0.6741292986338815 1.2760373802062406 0.20194230560709459 1.0 1.0 4 P16278,P06865
Irf3 mediated induction of type i ifn 0.643263543162309 1.2753224032281636 0.20219515130458698 1.0 1.0 5 Q9UJV9,P12956,P78527
Sting mediated induction of host immune responses 0.643263543162309 1.2753224032281636 0.20219515130458698 1.0 1.0 5 Q9UJV9,P12956,P78527
Hdl clearance 0.9680145268418047 1.2692289322633352 0.2043594248958316 1.0 1.0 2
Dopamine neurotransmitter release cycle 0.7583219492792344 1.268799904835265 0.20451243909262296 1.0 1.0 3
Amyloid fiber formation -0.608245720364751 -1.2686218976695856 0.20457595045206745 1.0 1.0 6 Q9UJY4,Q92542,P84243
Tp53 regulates transcription of genes involved in g2 cell cycle arrest -0.6184074091673222 -1.267432292416131 0.20500075923178818 1.0 1.0 8 Q99873,Q9Y3B8,P12004,P04637
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0.8256629076501077 1.2673157132952413 0.2050424241884592 1.0 1.0 1
Mitophagy 0.6489515237987187 1.264118807447197 0.20618738708495798 1.0 1.0 14 P21796,Q9NS69
Metabolic disorders of biological oxidation enzymes -0.6424371102570704 -1.2625900946899784 0.2067365294890351 1.0 1.0 5 P48506,P48507,P23526,P22570
Antigen activates b cell receptor bcr leading to generation of second messengers 0.7566615619565393 1.2623991278694244 0.20680520289531978 1.0 1.0 3 O43865
Mrna capping -0.6353295095236295 -1.2589430477318677 0.2080509035960798 1.0 1.0 12 Q09161,P19387
Trna processing in the mitochondrion -0.6778523489932777 -1.2581475713788655 0.20833839174436442 1.0 1.0 4 Q7L0Y3,O15091,Q99714,Q9BQ52
Ptk6 expression 0.8238341968911929 1.2581440449714356 0.20833966684210825 1.0 1.0 1
Complement cascade -0.8262724779030621 -1.2477124955197032 0.21213636362471266 1.0 1.0 1 Q99829
Unwinding of dna 0.6275361776865793 1.2474763869812668 0.21222287313138777 1.0 1.0 10 P33992,P33991,Q9Y248,P25205,P49736
Cholesterol biosynthesis 0.6594874426871729 1.243032340990409 0.21385591606628274 1.0 1.0 18 Q15392,Q15800,Q9BWD1,Q16850,Q14534,Q14739
Listeria monocytogenes entry into host cells -0.6049702795756707 -1.229563301539899 0.21886067961103572 1.0 1.0 7 Q9NWH9
Calcineurin activates nfat -0.9621558565492128 -1.228984074687301 0.2190777769795822 1.0 1.0 2 P62942
Negative regulation of flt3 -0.822005486132261 -1.2260827414635744 0.2201675397762466 1.0 1.0 1 P41240
Plasma lipoprotein assembly -0.7521672145224483 -1.2244114057913613 0.22079706876284044 1.0 1.0 3 P07237
Signaling by interleukins 0.3216475328743897 1.223743367533214 0.2210490542201924 1.0 1.0 107 P25787,P49721,P09601,Q14738,P11233,P07948,Q8IV63,Q13126,P08670,O43242,P28072,P51812,P28070,P61088,Q15008,P20618,Q9H0E2,P51665,P51809,Q15418,P28074,O00231,P63208,Q15750,P60900,P26038,Q53EL6
E2f enabled inhibition of pre replication complex formation 0.6312000591606901 1.2225459505277045 0.2215012382619337 1.0 1.0 5 Q9Y619
Inhibition of dna recombination at telomere -0.6122895973871261 -1.1952104974392035 0.2320047981704918 1.0 1.0 10 P46100,Q9UER7,P84243,P19387
Protein methylation -0.5972027662250656 -1.1941936539750304 0.23240222490679363 1.0 1.0 7 P38117,P13639,P55072
Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0.8110332215787882 1.1941552305914254 0.23241725190660345 1.0 1.0 1
Ticam1 traf6 dependent induction of tak1 complex 0.8104236513258166 1.1911182544993573 0.2336071645834803 1.0 1.0 1
Traf6 mediated induction of tak1 complex within tlr4 complex 0.8104236513258166 1.1911182544993573 0.2336071645834803 1.0 1.0 1
Irak2 mediated activation of tak1 complex 0.8104236513258166 1.1911182544993573 0.2336071645834803 1.0 1.0 1
Alpha protein kinase 1 signaling pathway 0.8104236513258166 1.1911182544993573 0.2336071645834803 1.0 1.0 1
Triglyceride catabolism -0.6254238261044355 -1.1878364607033993 0.23489784663830715 1.0 1.0 5 P43304,P62140,O60664,P62136
Enos activation -0.6603918970938889 -1.184077557994882 0.23638236287793912 1.0 1.0 4 O95865
Intrinsic pathway of fibrin clot formation 0.9427608702191073 1.180304125177688 0.2378792780506922 1.0 1.0 2
Formation of fibrin clot clotting cascade 0.9427608702191073 1.180304125177688 0.2378792780506922 1.0 1.0 2
Pyroptosis -0.7403906651166001 -1.1785951324901685 0.23855943078741193 1.0 1.0 3 P42574,P04637
Transferrin endocytosis and recycling 0.6116254610002185 1.1743709878666428 0.24024646067839361 1.0 1.0 10 Q15904,P02786,Q9Y487,Q93050
Polo like kinase mediated events -0.6567407909644029 -1.1685935227715398 0.24256743914498502 1.0 1.0 4 P53350,P49454
Platelet aggregation plug formation -0.6567383582208253 -1.1685832068905808 0.24257159739290568 1.0 1.0 4 P41240,P18031
Integrin signaling -0.6567383582208253 -1.1685832068905808 0.24257159739290568 1.0 1.0 4 P41240,P18031
Regulation of ifng signaling -0.6562792973127157 -1.1666366221974847 0.2433571472480569 1.0 1.0 4 P42224,P18031,Q06124
Regulation of innate immune responses to cytosolic dna 0.9379900889305077 1.1635640709967126 0.24460071890234136 1.0 1.0 2
Maturation of sars cov 1 spike protein -0.6542964846487319 -1.1582295382972057 0.24677037712383854 1.0 1.0 4 P14314,P27824,Q14697
Met activates pi3k akt signaling -0.9420936273965265 -1.1576991964399055 0.24698681200572414 1.0 1.0 2 Q9NWH9
Pentose phosphate pathway -0.5890680824578728 -1.157185187195215 0.24719670832445484 1.0 1.0 7 O95336,P37837,P29401,P52209,P60891
Negative regulation of the pi3k akt network -0.6080503951532883 -1.1549046155568856 0.24812948911527744 1.0 1.0 11 Q9NWH9
Miscellaneous transport and binding events 0.5920839750182104 1.1543175083810737 0.24837002100669325 1.0 1.0 7 P35611,Q8N4V1,Q9UEY8
Signaling by egfr in cancer 0.6449054301403345 1.154198565549525 0.2484187705490637 1.0 1.0 4 P19174,Q16543,P07900
Constitutive signaling by ligand responsive egfr cancer variants 0.6449054301403345 1.154198565549525 0.2484187705490637 1.0 1.0 4 P19174,Q16543,P07900
Constitutive signaling by egfrviii 0.6449054301403345 1.154198565549525 0.2484187705490637 1.0 1.0 4 P19174,Q16543,P07900
Nucleotide biosynthesis -0.6116948212195148 -1.1512181651217295 0.24964249390787518 1.0 1.0 12 O15067,P30566,P20839,P31939,P22102,P22234,P11172,P12268
Diseases of mismatch repair mmr 0.7276608722171409 1.1507814200698654 0.24982217040723476 1.0 1.0 3 P20585,P43246
Netrin mediated repulsion signals -0.8067662298079712 -1.1491503893805548 0.2504939735200935 1.0 1.0 1 Q06124
Activation of irf3 irf7 mediated by tbk1 ikk epsilon -0.8067662298079712 -1.1491503893805548 0.2504939735200935 1.0 1.0 1 Q06124
Nostrin mediated enos trafficking 0.8015848826577276 1.1471982027320151 0.25129971421508257 1.0 1.0 1
Choline catabolism -0.8061566595549996 -1.1460846732689667 0.25176011865303916 1.0 1.0 1 P49419
Fceri mediated ca 2 mobilization 0.6127352507609936 1.1418550477658889 0.25351427637663226 1.0 1.0 5 O43865
Heparan sulfate heparin hs gag metabolism 0.6409518931678256 1.1377569233198481 0.2552219968611449 1.0 1.0 4 P16278
Neurotransmitter release cycle -0.5885665022529206 -1.131637722569493 0.25778677397654737 1.0 1.0 8 P80404,P51649,O94925
Miro gtpase cycle -0.6119373771978467 -1.1286427294884298 0.259048577678886 1.0 1.0 5 Q8IXI1,Q8IWA4,Q8IXI2
Sumoylation of transcription factors -0.5770387818881861 -1.1265451997805769 0.2599348198324467 1.0 1.0 6 P61956,Q12888,P04637
Erythrocytes take up carbon dioxide and release oxygen -0.7997561718987979 -1.1139553846134385 0.26529832730132963 1.0 1.0 1 Q9UHQ9
Cdc6 association with the orc origin complex 0.7180070473984244 1.113746310447315 0.26538803582990034 1.0 1.0 3
Carboxyterminal post translational modifications of tubulin -0.6435860953615781 -1.1128459551585337 0.26577459462043973 1.0 1.0 4 Q9BVA1
Hemostasis -0.28892952493149854 -1.1102557045803334 0.2668888548448882 1.0 1.0 122 P14174,P41240,P37802,Q8IWA4,Q9NRW7,P84243,Q9Y6I9,P55145,Q92769,O00186,Q9H0B6,P63096,Q01518,O95235,P62873,P08754,P04899,Q9BVA1,Q9UHQ9,P07602,P21333,P04637,P62879,O75083,P18031,P23528,P23634,Q06124,Q14807,P04075,P13861,Q00535,P61586,P30626,P27144,P07947,O60333
Dap12 interactions 0.6047405350628074 1.1069875161904454 0.26829932576420834 1.0 1.0 5 P19174,P10321,P01889
Negative feedback regulation of mapk pathway -0.7219116539053109 -1.1068262767889556 0.268369045081968 1.0 1.0 3 Q02750
Regulation of insulin secretion -0.6096706180167705 -1.1037261187553324 0.26971196204774306 1.0 1.0 14 P62873,P62879,P29966,P04899
Class i mhc mediated antigen processing presentation 0.2948332625382671 1.1012065611346573 0.27080676678775584 1.0 1.0 124 P49721,O00231,Q9UIQ6,Q93034,P55786,P20618,Q9NZ08,P51572,P28072,Q15436,O43242,Q15386,P51665,P60900,Q8NEZ5,O94952,P28070,P28074
Role of phospholipids in phagocytosis 0.7144547911742167 1.1001403507415253 0.271270975184001 1.0 1.0 3 O43865
Ikk complex recruitment mediated by rip1 0.7136322049405305 1.0969914929252529 0.2726451109223653 1.0 1.0 3 Q9Y6K9,P61088
Ticam1 rip1 mediated ikk complex recruitment 0.7136322049405305 1.0969914929252529 0.2726451109223653 1.0 1.0 3 Q9Y6K9,P61088
Processing of capped intronless pre mrna -0.6159315565755263 -1.0968166290894588 0.2727215593968664 1.0 1.0 16 P62304,Q86U42,O94992,Q09161,P62318,Q10570
Toxicity of botulinum toxin type d botd 0.7903078329777521 1.0915122927690066 0.275047525787254 1.0 1.0 1
Neurotoxicity of clostridium toxins 0.7903078329777521 1.0915122927690066 0.275047525787254 1.0 1.0 1
Mrna splicing minor pathway -0.6523279642769626 -1.0897951505185604 0.27580339064914483 1.0 1.0 31 Q9BWJ5,Q9Y3B4,P55769,Q96DI7,Q09161,Q15393,Q9Y333,P62318,P62316,Q16629,P19387
Fgfr2 alternative splicing -0.6063482880310316 -1.0886423250305148 0.27631164452707435 1.0 1.0 14 Q09161,P19387
Trna modification in the mitochondrion -0.5732539341426727 -1.0853982807070808 0.2777452935479894 1.0 1.0 7 Q7L0Y3,Q9Y2Z2,Q99714
Nod1 2 signaling pathway 0.5702442289795866 1.078967128940165 0.2806023814359013 1.0 1.0 6 Q9Y6K9,Q96J02,Q15750,P61088
Methionine salvage pathway 0.6261413229236136 1.0763074664923962 0.2817897705056198 1.0 1.0 4
Met activates ptk2 signaling -0.9184958309942802 -1.0742917083982462 0.2826919601091493 1.0 1.0 2 Q9NWH9
Met interacts with tns proteins -0.9184958309942802 -1.0742917083982462 0.2826919601091493 1.0 1.0 2 Q9NWH9
Beta oxidation of butanoyl coa to acetyl coa 0.6240796112439158 1.0677747198517593 0.28562214412374676 1.0 1.0 4
Stimuli sensing channels 0.577309589521066 1.0627426167166936 0.2878986887745736 1.0 1.0 8
Pi5p regulates tp53 acetylation -0.9137195121950473 -1.0574841652179294 0.29029067763895666 1.0 1.0 2 Q13526,P04637
Ion transport by p type atpases -0.5895933892718201 -1.0509966558335768 0.2932601257554248 1.0 1.0 12 P23634,Q9NTM9
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7012429116535134 1.0496590981247111 0.2938748753091325 1.0 1.0 3 P00374
Aryl hydrocarbon receptor signalling -0.7054004625437352 -1.042913461839449 0.29698837425469016 1.0 1.0 3 O00170,Q15185
Ros and rns production in phagocytes 0.5720932665815972 1.0389278144442573 0.29883830938215716 1.0 1.0 8 Q93050
Creb1 phosphorylation through the activation of adenylate cyclase -0.7038868442011599 -1.0370680028945862 0.29970416595407867 1.0 1.0 3 P13861
Pka activation in glucagon signalling -0.7038868442011599 -1.0370680028945862 0.29970416595407867 1.0 1.0 3 P13861
Pka mediated phosphorylation of creb -0.7038868442011599 -1.0370680028945862 0.29970416595407867 1.0 1.0 3 P13861
Bbsome mediated cargo targeting to cilium -0.5625059466389679 -1.0367853429757743 0.29983590784806324 1.0 1.0 7 P50991,P78371,P48643,P17987,P49368
G alpha 12 13 signalling events -0.5860659572459217 -1.0350728434575294 0.3006348938307384 1.0 1.0 12 P62873,P62879,P61586
Cellular hexose transport 0.778725998171291 1.034795689250028 0.30076433652098267 1.0 1.0 1
Regulation of ifna signaling -0.7032631899969589 -1.0346602629098838 0.30082759983049256 1.0 1.0 3 P42224,P18031,Q06124
Regulation of tp53 activity through acetylation -0.5853018538649275 -1.031626627647184 0.3022470614251018 1.0 1.0 12 Q92769,O95696,P04637,Q13526
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.5800889153335007 1.0299731482189782 0.3030226107161793 1.0 1.0 10 P09601,P05067,Q96J02,Q15750,P08238,Q9Y6K9,P61088
Ptk6 regulates cell cycle 0.8990853658536584 1.0280506593636907 0.30392599841963497 1.0 1.0 2 P11802
Nephrin family interactions 0.5633242528739599 1.0227593848241943 0.3064216257392447 1.0 1.0 7 Q01082,Q9Y5K6,P46940,P12814
Pi3k akt signaling in cancer -0.5774767501420234 -1.016492885293923 0.30939473381170846 1.0 1.0 11 Q9NWH9
Diseases associated with glycosaminoglycan metabolism 0.6107492205642938 1.0127616818881848 0.31117400745001067 1.0 1.0 4 Q8NCH0,P06865
Post chaperonin tubulin folding pathway -0.5659822465450323 -1.0071281758770616 0.31387318274418985 1.0 1.0 9 Q9BVA1,O75347,P36404
Rho gtpases activate ktn1 -0.5606305196429445 -1.0053062068084513 0.31474942730595146 1.0 1.0 8 Q9H0B6,P61586
Sodium proton exchangers 0.771715940262117 1.0007335602024592 0.3169556378825722 1.0 1.0 1
Sphingolipid metabolism 0.6303622940113408 1.0006558964928054 0.31699319645961554 1.0 1.0 26 P51648,Q9NZJ7,Q06136,P27544,Q6ZMG9,P04062,P16278,O95470,Q96G23,Q13510,P06865
Sodium calcium exchangers -0.7768972874123632 -1.0002658098618018 0.317181888549638 1.0 1.0 1 P30626
Pyrimidine salvage 0.6882325639036937 1.0001775284726013 0.3172246021026739 1.0 1.0 3 Q08623
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation -0.6938331411042031 -0.9983119003374913 0.3181281387986301 1.0 1.0 3 P10809
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.6060040435718758 0.9932538428147284 0.32058626510470534 1.0 1.0 4 P30154,Q14738
Base excision repair ap site formation 0.605221617849594 0.9900414618069041 0.3221538537065105 1.0 1.0 4
Rna polymerase ii transcribes snrna genes -0.6294924921381853 -0.9895654816445272 0.3223865488892561 1.0 1.0 30 P55199,Q5TA45,Q09161,Q9NVM9
Erbb2 regulates cell motility -0.8935565131416715 -0.98687789352675 0.323702502746398 1.0 1.0 2 P61586
Mapk targets nuclear events mediated by map kinases 0.5652558789629156 0.9847640580193106 0.3247399791375485 1.0 1.0 9 P51812,Q15418,Q8IV63,Q14738
Erk mapk targets 0.5652558789629156 0.9847640580193106 0.3247399791375485 1.0 1.0 9 P51812,Q15418,Q8IV63,Q14738
Flt3 signaling -0.5789535607406272 -0.9845609983609194 0.3248397552020261 1.0 1.0 5 P41240,Q13322,Q06124
Apobec3g mediated resistance to hiv 1 infection -0.8926211688609854 -0.9836176697860071 0.3253035338539605 1.0 1.0 2 O75531
Ikba variant leads to eda id 0.7674489484913154 0.9801082968684756 0.3270326641022532 1.0 1.0 1
Sumoylation of immune response proteins 0.7674489484913154 0.9801082968684756 0.3270326641022532 1.0 1.0 1
Transcription of e2f targets under negative control by dream complex -0.6884719718202259 -0.9777008415000277 0.32822230546452724 1.0 1.0 3 Q13547,P12004
Transport and synthesis of paps 0.6821946962348556 0.9773069570900804 0.32841720986823963 1.0 1.0 3 Q8TB61
Prevention of phagosomal lysosomal fusion 0.6016271312373727 0.9752999575362833 0.3294114915470403 1.0 1.0 4 O14964
Ketone body metabolism -0.5763199036159075 -0.9731235225443976 0.33049191450635584 1.0 1.0 5 P35914,P24752
Synthesis of ketone bodies -0.5763199036159075 -0.9731235225443976 0.33049191450635584 1.0 1.0 5 P35914,P24752
Interleukin 23 signaling -0.8893007118770216 -0.9720558750768454 0.3310227521200071 1.0 1.0 2 P07237
Transport of connexons to the plasma membrane -0.6867988896545202 -0.971277456506469 0.33141013167666067 1.0 1.0 3 Q9BVA1
Gap junction assembly -0.6867988896545202 -0.971277456506469 0.33141013167666067 1.0 1.0 3 Q9BVA1
Processing of intronless pre mrnas -0.5800892840793249 -0.9701598502627892 0.3319668200928345 1.0 1.0 14 Q09161,Q86U42,Q10570
Peroxisomal lipid metabolism 0.5759057839124057 0.9685425383521462 0.33277348512758653 1.0 1.0 12 O14975,Q9BY49,Q15067,Q9UKG9,O15254,P51659
Irs activation -0.7692776592502183 -0.9628070265010578 0.335644373901552 1.0 1.0 1 Q13322
Ras signaling downstream of nf1 loss of function variants 0.7628771715940281 0.9581067002530509 0.3380089571818021 1.0 1.0 1
Cooperation of prefoldin and tric cct in actin and tubulin folding -0.5805566974999632 -0.9543520142472002 0.33990548730703063 1.0 1.0 15 P50990,P50991,P40227,Q13885,P78371,Q9NQP4,P48643,P17987,P49368,Q99832,Q9BVA1,Q99471
Antimicrobial peptides -0.8838414634145649 -0.9530889109061957 0.3405450241438137 1.0 1.0 2 P81605,Q96JM3
Transport of inorganic cations anions and amino acids oligopeptides 0.56764167664649 0.9518572821717208 0.3411693665142437 1.0 1.0 11 Q70HW3,Q9Y6M7,Q9UBX3,P30825,Q92581
Glucuronidation 0.6752235748902371 0.9509852256032909 0.34161187592746334 1.0 1.0 3
Defective factor ix causes hemophilia b 0.761353245961599 0.9507960445717988 0.34170792089969027 1.0 1.0 1
Gamma carboxylation transport and amino terminal cleavage of proteins 0.761353245961599 0.9507960445717988 0.34170792089969027 1.0 1.0 1
Defects of contact activation system cas and kallikrein kinin system kks 0.761353245961599 0.9507960445717988 0.34170792089969027 1.0 1.0 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.5455968302169115 0.9422413852840426 0.34606906997280484 1.0 1.0 7
Resolution of d loop structures 0.5455968302169115 0.9422413852840426 0.34606906997280484 1.0 1.0 7
Nrif signals cell death from the nucleus -0.8801063633091512 -0.9401437392422274 0.34714383567926 1.0 1.0 2 Q92542
Glycosaminoglycan metabolism 0.577855092774051 0.9379592475366828 0.34826535347503107 1.0 1.0 14 O43505,Q7LGA3,Q8NCH0,P15586,P16278,Q8TB61,P06865
Tnfr1 induced nfkappab signaling pathway -0.5329079523523257 -0.9274818696627911 0.353676400867033 1.0 1.0 6 Q6GQQ9,Q12933,P63244
Diseases associated with o glycosylation of proteins 0.8693658571903727 0.9261714342791983 0.3543568952247853 1.0 1.0 2
Attachment of gpi anchor to upar 0.5627283604337314 0.925197167151167 0.3548633567983468 1.0 1.0 5 O43292,Q92643
Fceri mediated mapk activation 0.5410687022900621 0.9217799996636424 0.35664334187754876 1.0 1.0 7 P28482,Q13177,P62993,Q16512,P07948,P19174
Assembly of active lpl and lipc lipase complexes 0.7543431880524251 0.9173243331518681 0.35897271010967313 1.0 1.0 1
Abortive elongation of hiv 1 transcript in the absence of tat -0.5594670482410962 -0.9159198539240233 0.3597089326663141 1.0 1.0 12 Q09161,P19387
Mitotic metaphase and anaphase 0.29425641962247717 0.9151839934986996 0.3600950461951742 1.0 1.0 136 P25787,P49721,Q8NBT2,Q14738,Q96EA4,Q9Y6G9,Q92621,Q92674,O43683,Q86Y07,P50402,O43242,P28072,Q06323,Q13257,P28070,Q14739,Q9BTX1,Q8N1F7,Q29RF7,Q15008,P20618,P51665,P06493,P28074,O00231,P50748,P57740,Q15691,Q8NFH4,P60900,Q8IXJ6,Q86XL3,Q14204
Mucopolysaccharidoses 0.5861860058809459 0.9123136152415244 0.36160364906381126 1.0 1.0 4 P15586,P16278
Bicarbonate transporters 0.7531240475464818 0.9115305471944876 0.36201589796651046 1.0 1.0 1
Downregulation of tgf beta receptor signaling -0.5345699566037682 -0.9114905838073457 0.36203694472601144 1.0 1.0 7 Q9Y3F4,P62136,Q9UNE7,P62140,Q9Y5K5
Sumoylation of dna methylation proteins -0.5956144368497347 -0.9109160202641822 0.36233962396070885 1.0 1.0 4 Q99496,Q9HC52
Ra biosynthesis pathway 0.6637865487593436 0.9080204178461326 0.36386743427739043 1.0 1.0 3
Caspase activation via dependence receptors in the absence of ligand -0.757695824443758 -0.9063731440199148 0.3647383825630848 1.0 1.0 1 P42574
Activation of caspases through apoptosome mediated cleavage -0.757695824443758 -0.9063731440199148 0.3647383825630848 1.0 1.0 1 P42574
Phenylalanine and tyrosine metabolism -0.5607740155494476 -0.9059027253063909 0.3649873417177032 1.0 1.0 5 P16930,P09417,P61457
Transport of bile salts and organic acids metal ions and amine compounds 0.6631036414469683 0.9054643968113449 0.36521941330905916 1.0 1.0 3 P53985
Synthesis of very long chain fatty acyl coas 0.5419400968567556 0.9022079551181519 0.36694640975991 1.0 1.0 8 Q4G176
Wnt mediated activation of dvl 0.6611771881671238 0.8982600531851881 0.3690469239658185 1.0 1.0 3 P19784,P68400
Ephrin signaling 0.5559097012178531 0.896036810350303 0.3702331036806865 1.0 1.0 5 O00560,Q16512,Q14155
Cyclin d associated events in g1 0.5591206328749806 0.8927135086280863 0.37201061433330285 1.0 1.0 12 P63208,P11802,P07948,P24941
Hs gag degradation 0.6591378548642401 0.8906435651944388 0.37312041962199305 1.0 1.0 3
Tnfr1 induced proapoptotic signaling -0.6638003716394668 -0.8834821454577904 0.3769758251077002 1.0 1.0 3 Q6GQQ9,Q12933
Maturation of sars cov 2 nucleoprotein -0.5552225339252426 -0.8820385768471384 0.37775594625861775 1.0 1.0 5 Q99873,P78362
Egfr downregulation 0.5362108951817895 0.8764750509779379 0.38077183372945056 1.0 1.0 8 O14964,Q9Y6I3
Purine salvage -0.5873000393593115 -0.8763028846409912 0.38086539728280266 1.0 1.0 4 P00491,P00492
Cd209 dc sign signaling 0.575767920222884 0.8701804476201351 0.38420179933355936 1.0 1.0 4 Q16512,P07948
Formation of senescence associated heterochromatin foci sahf -0.5346273406595565 -0.8673601770400953 0.3857446942520819 1.0 1.0 9 P10412,P16403,P04637,Q9Y294
Mitochondrial calcium ion transport 0.5690566599407186 0.8618007847825919 0.38879715300479134 1.0 1.0 16 Q99623,Q9H300,Q96TA2,P21796,P45880
Foxo mediated transcription -0.5425419966007786 -0.8608386101659914 0.3893269366862826 1.0 1.0 11 Q9Y3B8,P61981,Q92769,P04179
Loss of function of mecp2 in rett syndrome -0.5491946292789486 -0.8562243943856477 0.39187367174331356 1.0 1.0 5 O75376
Activation of anterior hox genes in hindbrain development during early embryogenesis -0.5582466601822395 -0.8553350070110605 0.39236571275643417 1.0 1.0 15 Q15291,O75376,P61964,P84243,P19387
Trafficking and processing of endosomal tlr 0.8476377657060673 0.8529289620754827 0.3936986995748031 1.0 1.0 2
Branched chain amino acid catabolism -0.5615425477530639 -0.8528592877692805 0.39373734104544944 1.0 1.0 16 P26440,P30084,Q02252,P45954,P31937,Q96RQ3,P24752,Q6NVY1,P21953,P09622
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.5194532753919121 0.8487870603436577 0.39599979161490806 1.0 1.0 6 Q15067,P51659
Advanced glycosylation endproduct receptor signaling -0.5189161125226527 -0.842238745443526 0.3996543302356168 1.0 1.0 7 P14314
Receptor mediated mitophagy 0.5682731221529586 0.840082352919364 0.400862213855504 1.0 1.0 4 P19784,P68400
Signalling to ras 0.6447087526685081 0.8370715175180029 0.4025523692588453 1.0 1.0 3 P11233,Q16539
Signaling by ntrk3 trkc 0.6447087526685082 0.8370715175180029 0.4025523692588453 1.0 1.0 3 P19174,Q8WX92
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex -0.5321284557278443 -0.8354079082388026 0.4034880786695423 1.0 1.0 10 O96017,P61981,Q04917,P27348,Q9Y3B8,P62258,P63104
Vitamin b1 thiamin metabolism 0.8423551061040492 0.835311684703528 0.40354224013193774 1.0 1.0 2
Sirt1 negatively regulates rrna expression -0.576388177653656 -0.831134792330511 0.4058974867925773 1.0 1.0 4 P84243
Diseases of dna repair 0.5403317422723516 0.8292441963883043 0.4069662406980492 1.0 1.0 11 P49959,P43246,P20585,Q9UQ84,P78549,P51530,P52701
Apoptosis induced dna fragmentation -0.5304554652864012 -0.8280885089603961 0.4076203767036555 1.0 1.0 10 O00273,Q14974,P16403,P42574,P10412
Nicotinamide salvaging 0.8398929480093419 0.8271282900922767 0.4081643510291004 1.0 1.0 2
Transcriptional regulation by tp53 -0.2695579571640824 -0.8263209476316994 0.4086220536994152 1.0 1.0 122 O14548,O95696,Q99873,P32119,Q9Y2Q5,Q9Y3B8,Q92769,O96017,O94925,Q9H9B1,Q13526,P55199,Q9UIV1,P04637,P10606,Q9ULW0,Q15370,P30044,Q9UER7,Q00535,P61981,P14854,P12004,P19387
S phase 0.37524302699636275 0.8261162778221245 0.40873813467864784 1.0 1.0 98 P25787,P49721,Q9UJX4,P11802,O43242,P18858,P28072,Q9Y248,Q06323,P25205,P28070,Q29RF7,Q07864,Q15008,P20618,P24941,P51665,P41440,Q9UJX5,P49642,P49736,P49841,P51530,Q9UQE7,P28074,P35251,O00231,P33992,P33991,P63208,Q9Y619,P60900
Defective intrinsic pathway for apoptosis -0.554446724112307 -0.8217641704872538 0.4112111293159244 1.0 1.0 16 P02545,P04637,P04179,Q00535,P32119,O15446
Chylomicron clearance -0.8451858872138057 -0.8205763298709438 0.41188763487696334 1.0 1.0 2 P01130
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.6396308787219861 0.8183631339074561 0.41314986597494086 1.0 1.0 3
Traf6 mediated irf7 activation -0.646386200465037 -0.8177746572489916 0.4134858714809557 1.0 1.0 3 Q12933
Sumo is proteolytically processed -0.7391039317281245 -0.8172648964999487 0.4137770628996438 1.0 1.0 1 P61956
Heme signaling 0.522803027057617 0.8166638347482663 0.4141205642120971 1.0 1.0 8 P09601,Q96EB6
Synthesis of 5 eicosatetraenoic acids 0.7327034440719299 0.8158265698871302 0.4145993345323129 1.0 1.0 1
Neurofascin interactions 0.7317890886924723 0.8116054971469875 0.41701803598049825 1.0 1.0 1
Generation of second messenger molecules 0.5607267275055359 0.8099786656293391 0.4179524375182786 1.0 1.0 4 P19174,Q16512
Suppression of apoptosis 0.5607077486272184 0.8099032281992417 0.4179957963342904 1.0 1.0 4 P49840,Q63HN8,P23246
Sensing of dna double strand breaks 0.5603690945080544 0.8085573798298485 0.4187697884057491 1.0 1.0 4 P52292,P49959
Gab1 signalosome -0.643706559597581 -0.807735196036233 0.4192430377429224 1.0 1.0 3 P41240,Q06124
Metabolism of angiotensinogen to angiotensins 0.7308747333130148 0.8073903576343615 0.4194416204618361 1.0 1.0 1
Runx1 regulates expression of components of tight junctions 0.8314907714308502 0.7993413946099298 0.42409248251859877 1.0 1.0 2
Synthesis of pips at the early endosome membrane -0.5030905209166918 -0.7958213955860703 0.4261358540005422 1.0 1.0 6 Q13496,Q13614
Cation coupled chloride cotransporters 0.7275220969216705 0.7919864999349827 0.42836854795232604 1.0 1.0 1
Kinesins -0.5475941372024519 -0.7919550149257036 0.4283869067949204 1.0 1.0 16 Q14807,Q9H0B6,O95235,Q9BVA1,O60333
Rna polymerase ii transcription termination -0.5951319053629711 -0.7873682784783812 0.43106631062085676 1.0 1.0 42 P84103,Q05519,Q9Y5S9,Q07955,P62304,Q8IYB3,P26368,O00148,Q86U42,Q13838,Q09161,O94992,Q13769,P38919,Q96J01,P62318,Q16629,Q10570
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.5398914436457827 0.7872758940315886 0.43112037790389657 1.0 1.0 13 P46379,P51648,P09601,P50402
Camk iv mediated phosphorylation of creb 0.6309850564196369 0.7867026849982717 0.4314559319472697 1.0 1.0 3 P52292,Q13557
Creb phosphorylation 0.8271341463414899 0.7850220924393461 0.43244061565352476 1.0 1.0 2 Q15418
Integration of energy metabolism -0.5713727670367849 -0.7840831570471913 0.4329913176902165 1.0 1.0 24 P62879,P62873,P04899,P29966,Q13085,O00763
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5330480018886542 0.776719537803875 0.43732425723069746 1.0 1.0 12 O60725
Sema4d in semaphorin signaling -0.5138536792617435 -0.7766345945414096 0.4373743851712293 1.0 1.0 9 Q9NWH9,P60660,P61586
Triglyceride metabolism 0.5030315068254377 0.7758826212515577 0.43781829467855493 1.0 1.0 6
Glycerophospholipid catabolism 0.7235598902773545 0.7738894944275435 0.4389961426893816 1.0 1.0 1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain -0.50306457382296 -0.7730800918520137 0.43947498229474924 1.0 1.0 7 Q9UIV1,P04637,Q9C0C2
Uptake and function of anthrax toxins -0.6340347666971644 -0.7716785201422327 0.44030485577348655 1.0 1.0 3 Q02750,Q8WUM4,P36507
Pp2a mediated dephosphorylation of key metabolic factors 0.6261055199755967 0.768949412214126 0.4419233423611544 1.0 1.0 3 P30154,Q14738
Interleukin 4 and interleukin 13 signaling 0.5312703946222226 0.7689110951766212 0.4419460903427537 1.0 1.0 12
Opioid signalling -0.5555868582396937 -0.766019317879628 0.44366480784985374 1.0 1.0 20 P62136,P62879,P62873,P08754,P04899,Q00535
Anti inflammatory response favouring leishmania parasite infection -0.5414710174951242 -0.765518649506983 0.4439627655485976 1.0 1.0 16 P62873,P62879,P08754,P04899
Arachidonate production from dag 0.8210365853658766 0.7650877443523566 0.4442192972270056 1.0 1.0 2 Q8NCG7
Rnd1 gtpase cycle 0.5472486085557207 0.7648970761935854 0.4443328351019542 1.0 1.0 16 P51648,Q13017,Q9UJF2,Q8TAA9,Q9BXS4,P02786,O75976,P38159
Activated ntrk2 signals through cdk5 -0.8280632983361844 -0.763110887955489 0.4453972672078834 1.0 1.0 2 Q00535
Pre notch expression and processing -0.5144494948264965 -0.7586985580215023 0.4480328996962719 1.0 1.0 10 P84243,P04637
Clec7a dectin 1 induces nfat activation 0.817104684137299 0.7523023365770386 0.45186926303039243 1.0 1.0 2
Abacavir transport and metabolism 0.8167854377607429 0.7512666778085559 0.4524921790126837 1.0 1.0 2
Acyl chain remodelling of pc -0.7235598902773489 -0.7444335970893581 0.45661419971471173 1.0 1.0 1 Q8NF37
Notch1 intracellular domain regulates transcription -0.4963727424771181 -0.7442358626721629 0.4567337953509547 1.0 1.0 7 O75376,Q92769
Post translational modification synthesis of gpi anchored proteins 0.4956643178357814 0.7435373912749176 0.45715639243723594 1.0 1.0 6 O43292
Transcriptional regulation by e2f6 -0.5054722226748208 -0.7405969472703531 0.4589378595322846 1.0 1.0 9 Q15022,P45973,P38398,Q99496,Q9H9B1
Sars cov 1 infection -0.5148100801238265 -0.740508637723927 0.45899142194909803 1.0 1.0 11 P17844,P14314,P27824,P55072
Signaling by ntrk2 trkb -0.5216081887068137 -0.7396922864718267 0.45948672956021075 1.0 1.0 5 Q00535,Q06124
Dopamine clearance from the synaptic cleft 0.7156354769887223 0.7380628738505449 0.4604762430834688 1.0 1.0 1
Stat3 nuclear events downstream of alk signaling -0.5533862111043233 -0.7371214980671575 0.4610484667376209 1.0 1.0 4 P40763,Q13547,Q92769,Q96ST3
Carnitine metabolism -0.5200722111614074 -0.7332955999831146 0.4633781580964471 1.0 1.0 5 P50416,Q13085,O00763
Activation of rac1 0.5405735204392993 0.7307368807058412 0.4649398838836929 1.0 1.0 4 Q13177,Q16512,O94813
Serine biosynthesis -0.8182926829267719 -0.7307327220473323 0.46494242451988965 1.0 1.0 2 O43175,Q9Y617
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids -0.5515117444854498 -0.7295451147464158 0.4656682815667834 1.0 1.0 4 P11310,P55084
Diseases of programmed cell death -0.5636976597825588 -0.7292941726156966 0.465821736126528 1.0 1.0 26 P04637,P04179,Q00535,P32119,Q12933,P09884,P84243,O15446
Assembly of collagen fibrils and other multimeric structures 0.6146054801651277 0.7274688402782117 0.4669387968101115 1.0 1.0 3
Tlr3 mediated ticam1 dependent programmed cell death 0.7131971959768355 0.7271424448974634 0.46713869963387067 1.0 1.0 1
Trif mediated programmed cell death 0.7131971959768355 0.7271424448974634 0.46713869963387067 1.0 1.0 1
Trp channels 0.7131971959768355 0.7271424448974634 0.46713869963387067 1.0 1.0 1
Ddx58 ifih1 mediated induction of interferon alpha beta -0.5362205831572668 -0.7271355352640513 0.4671429319935294 1.0 1.0 17 Q12933,Q15366,Q13526,Q86UT6,O94826
Runx2 regulates osteoblast differentiation -0.6217781999524535 -0.7264309661786617 0.467574613507586 1.0 1.0 3 P07947
Ras processing 0.5389279945249945 0.7243499235796456 0.4688509347757033 1.0 1.0 4 O60725
Downregulation of erbb2 erbb3 signaling -0.8163354374262529 -0.7242859430489352 0.4688902051045458 1.0 1.0 2 P40818
Trna modification in the nucleus and cytosol -0.542086098003012 -0.7222465965142877 0.47014287970597746 1.0 1.0 19 Q9UET6,Q9Y3C4,Q2VPK5
Oncogene induced senescence 0.4957123430728097 0.7204937446934778 0.47122104974736634 1.0 1.0 7 Q9HCE1
Synaptic adhesion like molecules 0.490341803017395 0.7203297286373219 0.47132200490536835 1.0 1.0 6
Recognition and association of dna glycosylase with site containing an affected purine 0.8069340516326691 0.719494982379077 0.47183599270543275 1.0 1.0 2
Beta oxidation of lauroyl coa to decanoyl coa coa 0.5357164017360381 0.7119241738181347 0.47651173184683127 1.0 1.0 4
Cooperation of pdcl phlp1 and tric cct in g protein beta folding -0.520265388806098 -0.7087615533418112 0.4784724599737409 1.0 1.0 14 P62873,P62879,P40227,P48643
Disassembly of the destruction complex and recruitment of axin to the membrane 0.5109933085992467 0.7080190228978642 0.4789334443297628 1.0 1.0 5 P49841,Q14738
Beta catenin phosphorylation cascade 0.5109933085992467 0.7080190228978642 0.4789334443297628 1.0 1.0 5 P49841,Q14738
Signaling by ctnnb1 phospho site mutants 0.5109933085992467 0.7080190228978642 0.4789334443297628 1.0 1.0 5 P49841,Q14738
Rna polymerase i promoter escape -0.5158884832613794 -0.7078615498856529 0.4790312392871092 1.0 1.0 13 Q3B726,P84243,O15446
Separation of sister chromatids 0.29389872666803313 0.7071180322750265 0.4794931308657824 1.0 1.0 106 P25787,P49721,Q8NBT2,Q14738,Q96EA4,Q9Y6G9,Q92674,O43683,O43242,P28072,Q06323,P28070,Q29RF7,Q15008,P20618,P51665,P28074,O00231,P50748,P57740,Q15691,Q8NFH4,P60900,Q14204
Organic anion transporters 0.8030376892808508 0.70703252003177 0.47954626876921 1.0 1.0 2
Proton coupled monocarboxylate transport 0.8024390243902437 0.7051231029711428 0.48073363027669025 1.0 1.0 2 P53985
Cytosolic sulfonation of small molecules 0.5075564040193385 0.6940076829711216 0.48767739074983485 1.0 1.0 5 Q8TB61
Pd 1 signaling -0.8070121951218959 -0.6937674917421409 0.4878280324314854 1.0 1.0 2 P41240,Q06124
Repression of wnt target genes -0.5415581552244649 -0.6895633506822604 0.4904688214468318 1.0 1.0 4 Q13363
Gap junction trafficking and regulation -0.49778377616130043 -0.6878783414707151 0.49152939665890427 1.0 1.0 10 P09497,Q9BVA1,P09496
Aggrephagy -0.5108796474786093 -0.6867980155712796 0.49221002048518203 1.0 1.0 13 P55072,Q13409,P63167,Q9BVA1,Q99497
Chondroitin sulfate dermatan sulfate metabolism 0.6023634382710694 0.6839255122357497 0.4940222030998549 1.0 1.0 3 Q8NCH0
Signaling by tgfb family members -0.5342450989598283 -0.6752922777597967 0.49949008915633586 1.0 1.0 20 Q9Y3F4,O75376,P62136,Q13547,Q7Z3T8,Q9UPN9,P61586,P62942,P61081,Q9UNE7,P62140,Q9Y5K5
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.489679506874497 0.672169671364657 0.501475686402554 1.0 1.0 8 Q15418,Q14168
Syndecan interactions 0.5244752155088215 0.6688709542757628 0.5035777999395619 1.0 1.0 4 Q9Y296
Rho gtpases activate nadph oxidases -0.5040344388719181 -0.6672092997121192 0.5046384517228693 1.0 1.0 5 Q13526
Synthesis of ip3 and ip4 in the cytosol 0.5971332723391304 0.6655347214583386 0.5057085431587709 1.0 1.0 3 P19174,Q13572
Gap junction degradation -0.47138344829316026 -0.6602498432651783 0.5090935112418313 1.0 1.0 6 P09497,P09496
Calnexin calreticulin cycle -0.48064441686097903 -0.6564263280533571 0.5115498550725581 1.0 1.0 8 P27797,P14314,P27824,P30101
Interleukin 35 signalling -0.6022446584977015 -0.6555213031423252 0.5121321751593535 1.0 1.0 3 P42224,P27824
Interleukin 27 signaling -0.6022446584977015 -0.6555213031423252 0.5121321751593535 1.0 1.0 3 P42224,P27824
Tysnd1 cleaves peroxisomal proteins 0.49795440594269613 0.6552204603142684 0.5123258229721632 1.0 1.0 5 Q15067
Signaling by cytosolic fgfr1 fusion mutants -0.48027766805991123 -0.6549010942043856 0.512531435704334 1.0 1.0 8 P42224,Q16630,Q32MZ4,O15164,Q9UBW7,Q92614,P40763
Binding of tcf lef ctnnb1 to target gene promoters -0.7037488570557722 -0.654270578369085 0.5129374975998164 1.0 1.0 1 P35222
Runx3 regulates wnt signaling -0.7037488570557722 -0.654270578369085 0.5129374975998164 1.0 1.0 1 P35222
Rora activates gene expression -0.6010777051726199 -0.6513375712743043 0.5148286002477476 1.0 1.0 3 P50416
Fructose metabolism -0.6009121230635591 -0.6507444443824101 0.5152114680635043 1.0 1.0 3 P15121
Beta oxidation of hexanoyl coa to butanoyl coa 0.4964057249341556 0.6490167428579894 0.5163275542723751 1.0 1.0 5
Formation of the early elongation complex -0.5059235949187363 -0.6488950567456718 0.5164062100940245 1.0 1.0 14 Q09161
Displacement of dna glycosylase by apex1 0.5191740734584395 0.6488221622862265 0.5164533308005621 1.0 1.0 4
Signaling by notch1 -0.48824845663817257 -0.6481388785914338 0.5168951299131905 1.0 1.0 10 O75376,Q92542,Q92769
Glutathione conjugation -0.5057139700307554 -0.648030673185556 0.5169651115611571 1.0 1.0 14 O14880,P48506,P48507,Q9Y2Q3,P10768,P28161,O43708,P78417,P21266,P14550
Diseases of glycosylation 0.541102122310771 0.6471091240927556 0.517561320569403 1.0 1.0 22 O43505,Q8NCH0,Q9BV10,P10619,P16278,Q9UKM7,P06865
Ovarian tumor domain proteases -0.49241918577674104 -0.6464229093607307 0.5180055077692871 1.0 1.0 11 P04637,P55072,Q5VVQ6,P61586,Q6GQQ9
Runx2 regulates bone development -0.5305829414378195 -0.6460132706464556 0.5182707610961788 1.0 1.0 4 P07947
Signaling by tgf beta receptor complex -0.5234782297527212 -0.6443177112303337 0.5193694329530589 1.0 1.0 19 Q9Y3F4,O75376,P62136,Q13547,Q9UPN9,P61586,P62942,P61081,Q9UNE7,P62140,Q9Y5K5
Early phase of hiv life cycle -0.4720178992711594 -0.6414287323901062 0.521244170267912 1.0 1.0 7 O75531
Atf6 atf6 alpha activates chaperone genes -0.7893471471544939 -0.6368770951323666 0.5242049034025529 1.0 1.0 2 P27797
Scavenging by class a receptors -0.7893471471544939 -0.6368770951323666 0.5242049034025529 1.0 1.0 2 P27797
Atf6 atf6 alpha activates chaperones -0.7893471471544939 -0.6368770951323666 0.5242049034025529 1.0 1.0 2 P27797
Glycogen synthesis 0.5154899158284435 0.6349916474775548 0.5254338625286747 1.0 1.0 4 Q16851
Ncam signaling for neurite out growth 0.49236434674573826 0.6329000109111959 0.5267989406883187 1.0 1.0 5 Q01082,P62993
G2 m dna replication checkpoint 0.5876791704788138 0.6326423147689139 0.5269672477604304 1.0 1.0 3 P06493,Q99640
Laminin interactions -0.6982627247790278 -0.6299039624519012 0.528757420230173 1.0 1.0 1 P05556
Elastic fibre formation -0.6982627247790278 -0.6299039624519012 0.528757420230173 1.0 1.0 1 P05556
Fibronectin matrix formation -0.6982627247790278 -0.6299039624519012 0.528757420230173 1.0 1.0 1 P05556
Other semaphorin interactions -0.6982627247790278 -0.6299039624519012 0.528757420230173 1.0 1.0 1 P05556
Molecules associated with elastic fibres -0.6982627247790278 -0.6299039624519012 0.528757420230173 1.0 1.0 1 P05556
Metabolism of nitric oxide nos3 activation and regulation -0.4637335218698113 -0.6284654590079691 0.5296990672325483 1.0 1.0 6 O95865
Antigen processing ubiquitination proteasome degradation 0.34703714473717523 0.6243071376524445 0.5324258972935454 1.0 1.0 99 P49721,O00231,Q9UIQ6,Q93034,P55786,P20618,O43242,Q15386,P28072,P51665,P60900,Q8NEZ5,O94952,P28070,P28074
Cytosolic trna aminoacylation -0.5308134799171443 -0.6235557003860798 0.5329194112568867 1.0 1.0 23 P54136,P49588,P49591,Q13155,Q15046,P41252,Q9NSD9,Q15181,P26640,P26639,P23381,P14868,P07814,P41250,P56192,Q12904
Beta oxidation of octanoyl coa to hexanoyl coa 0.48918648164689105 0.6203026830211421 0.535058528846811 1.0 1.0 5
Signalling to erks -0.47136902775962986 -0.6181479966092389 0.5364777861570043 1.0 1.0 8 Q02750,P46109
Tight junction interactions 0.7738377240561104 0.6157232466778461 0.5380771918414016 1.0 1.0 2
Regulation of tp53 activity through association with co factors -0.7820495898781589 -0.6137652036073827 0.5393704941258948 1.0 1.0 2 P04637
Cell cycle checkpoints 0.2806946072800035 0.6129557782708556 0.5399055801995041 1.0 1.0 144 P25787,P49721,Q8NBT2,Q14738,Q96EA4,Q9Y6G9,Q92674,O43683,O43242,P28072,Q06323,Q13257,P28070,P61088,Q15008,P20618,P24941,O96028,P51665,Q9UQ84,P06493,P49736,P28074,Q9NYZ3,P50748,O00231,P57740,Q9Y619,Q15691,Q8NFH4,P60900,Q14204
Interleukin 6 signaling -0.5902634844179023 -0.6128792903228366 0.5399561577535257 1.0 1.0 3 P42224,Q06124
Interleukin 6 family signaling -0.5902634844179023 -0.6128792903228366 0.5399561577535257 1.0 1.0 3 P42224,Q06124
Interleukin 20 family signaling -0.5902634844179023 -0.6128792903228366 0.5399561577535257 1.0 1.0 3 P42224,Q06124
Transcriptional regulation of white adipocyte differentiation -0.5081276403694296 -0.6103805756794444 0.5416097323290974 1.0 1.0 17 O75376,Q13503,O60244,P24468,Q96EK7,Q71SY5
Glycosphingolipid metabolism 0.5069278525718287 0.6091298307586251 0.5424383861585997 1.0 1.0 15 Q9NZJ7,P04062,P16278,Q13510,P06865
Intrinsic pathway for apoptosis -0.5144785647323459 -0.6075572539815141 0.5434811588166077 1.0 1.0 19 P04637,P61981,P63167,Q04917,P42574,P27348,Q9Y3B8,P62258,P63104
Gpcr ligand binding -0.48235238160377686 -0.6052540599924655 0.5450102008963846 1.0 1.0 11 P62879,P62873
Golgi cisternae pericentriolar stack reorganization 0.4836632159234727 0.6049695791179397 0.5451992098740066 1.0 1.0 10 P06493,Q9H0U4
Ubiquinol biosynthesis 0.6848521792136513 0.6042033541399655 0.5457084512221553 1.0 1.0 1
Defects in cobalamin b12 metabolism 0.5064433597826392 0.6014104541017783 0.5475666374298873 1.0 1.0 4
Cobalamin cbl vitamin b12 transport and metabolism 0.5064433597826392 0.6014104541017783 0.5475666374298873 1.0 1.0 4
Downregulation of smad2 3 smad4 transcriptional activity -0.4569595977350368 -0.6006799687616255 0.548053163322684 1.0 1.0 6 Q13547,O75376,Q9UPN9
Sialic acid metabolism 0.506060908181823 0.600003191664516 0.548504108419902 1.0 1.0 4 P16278
Irak1 recruits ikk complex 0.7676829268292682 0.5969930763317228 0.5505120031825661 1.0 1.0 2 P61088
Pyruvate metabolism and citric acid tca cycle -0.5449260363323399 -0.5943643320290536 0.5522684592535407 1.0 1.0 33 P21912,P36957,O43837,P07954,Q8NCN5,P31040,Q9P2R7,P40926,P07195,P10515,Q6P587,Q99798,P50213,P09622,Q96I99,Q04760,O75390,P53597,Q02218,P08559
Constitutive signaling by akt1 e17k in cancer 0.4823555686063697 0.5934619083142644 0.5528720681032433 1.0 1.0 5 P42345
Diseases of carbohydrate metabolism 0.4750107327706705 0.5892956238315109 0.5556629799852499 1.0 1.0 9 P10253,O43826,P16278
Wnt5a dependent internalization of fzd2 fzd5 and ror2 -0.4642696971427241 -0.5892921508347446 0.5556653093436088 1.0 1.0 8 P09497,P09496
Activation of the tfap2 ap 2 family of transcription factors 0.681194757695821 0.5889339336146057 0.5559055932381427 1.0 1.0 1
Erks are inactivated 0.458904294534615 0.5866177592409806 0.5574604526419162 1.0 1.0 6 Q8IV63,Q14738
Dscam interactions 0.5737492898480788 0.5850761140462034 0.5584965389198362 1.0 1.0 3 Q16539
Role of second messengers in netrin 1 signaling 0.6799756171898776 0.5838770801862995 0.5593030144500384 1.0 1.0 1
Egfr interacts with phospholipase c gamma 0.6799756171898776 0.5838770801862995 0.5593030144500384 1.0 1.0 1
Phospholipase c mediated cascade fgfr2 0.6799756171898776 0.5838770801862995 0.5593030144500384 1.0 1.0 1
Phospholipase c mediated cascade fgfr4 0.6799756171898776 0.5838770801862995 0.5593030144500384 1.0 1.0 1
Transport of fatty acids -0.687595245352025 -0.5833574380002241 0.5596527035795498 1.0 1.0 1 Q6P1M0
Acyl chain remodeling of cl -0.581062454049558 -0.5806335252936003 0.5614874722608729 1.0 1.0 3 P55084
Fasl cd95l signaling 0.6784516915574484 0.5775795701364521 0.5635480032589433 1.0 1.0 1
Formation of atp by chemiosmotic coupling 0.471523486061609 0.57491703794474 0.5653474063932338 1.0 1.0 9 O75964,P56385,P06576
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.5697718583031335 0.57170697654009 0.5675205072122536 1.0 1.0 3 O14975
Signaling by insulin receptor 0.4975129942769313 0.5702141476816747 0.5685324615870817 1.0 1.0 15 Q15904,Q93050
Signaling by fgfr -0.5050053204630208 -0.5696040814576199 0.568946259595648 1.0 1.0 19 Q09161
Signaling by fgfr2 -0.5050053204630208 -0.5696040814576199 0.568946259595648 1.0 1.0 19 Q09161
Synthesis of pips at the golgi membrane 0.46420281523925133 0.5654356514465491 0.571777481044504 1.0 1.0 8 Q9BTU6,Q99570,O00443,Q01968
Interleukin 17 signaling 0.4951858538713481 0.5607052093775909 0.5749985153297803 1.0 1.0 15 Q8IV63,P63208,Q14738,Q15750,P51812,Q15418,Q9Y6K9,P61088
Rnd3 gtpase cycle 0.5133498081624035 0.5581676902479753 0.5767298814737023 1.0 1.0 20 Q13464,Q13017,Q9UJF2,Q8TAA9,O75976,P38159,Q07065
Signaling by met -0.4947541237749887 -0.5569880162661818 0.5775356169285559 1.0 1.0 17 P46109,P40818,Q9NWH9,P18031,Q06124,Q96S59
Chylomicron assembly -0.7636730821926285 -0.55668902918822 0.5777399138493089 1.0 1.0 2 P07237
Translation of sars cov 1 structural proteins -0.4499387805923849 -0.5518756639369826 0.5810335428435751 1.0 1.0 7 P14314,P27824,Q14697
Keratan sulfate biosynthesis 0.7521092554746378 0.5504993858623267 0.5819768980000963 1.0 1.0 2
Synthesis of pe 0.7513880519057851 0.5483790889993108 0.583431631740186 1.0 1.0 2
Hyaluronan metabolism -0.5049113703441392 -0.5467788143203263 0.584530699695601 1.0 1.0 4 Q9UHD1,P07686,P08236
Hyaluronan uptake and degradation -0.5049113703441392 -0.5467788143203263 0.584530699695601 1.0 1.0 4 Q9UHD1,P07686,P08236
Late endosomal microautophagy -0.443454976271589 -0.5464024565619858 0.5847893218563636 1.0 1.0 6 Q99497
Nuclear events kinase and transcription factor activation 0.4784495442244258 0.5453046267177323 0.5855440225277493 1.0 1.0 12 Q8IV63,P30154,P50570,Q14738,P51812,Q15418
Translation of replicase and assembly of the replication transcription complex 0.6705272782688163 0.5452660360540453 0.5855705598193721 1.0 1.0 1
Estrogen dependent nuclear events downstream of esr membrane signaling 0.5605367490088541 0.5410580156709697 0.5884675952631429 1.0 1.0 3 P31751,O14980
Signaling by fgfr in disease -0.4971147282478015 -0.5386230052864653 0.5901470104086532 1.0 1.0 19 Q09161,Q32MZ4,P19387
Hdacs deacetylate histones -0.47425727469816403 -0.5384492324275486 0.5902669450703586 1.0 1.0 13 O00422,O75376,Q8WXI9,Q13547,O75446,Q92769
Downstream signal transduction -0.4411699300458827 -0.5373775785978769 0.591006827701337 1.0 1.0 6 P42224,P46109,Q06124
Signaling by pdgf -0.4411699300458827 -0.5373775785978769 0.591006827701337 1.0 1.0 6 P42224,P46109,Q06124
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 -0.4706649495359656 -0.5347749625922807 0.5928054781940961 1.0 1.0 5 P62873
Incretin synthesis secretion and inactivation -0.4706649495359656 -0.5347749625922807 0.5928054781940961 1.0 1.0 5 P62873
Molybdenum cofactor biosynthesis 0.5585175999371719 0.5344331225907626 0.5930419078435756 1.0 1.0 3
Aflatoxin activation and detoxification -0.7554878048780028 -0.531826480933099 0.5948461802715843 1.0 1.0 2 O14880,O43488
Alpha oxidation of phytanate 0.4660946978219678 0.5309976721230777 0.5954203923086019 1.0 1.0 5 P51648,O14975,Q9BY49
Recycling of eif2 gdp -0.44901279937604904 -0.5287307761842385 0.5969922244581669 1.0 1.0 8 P41091,Q9NR50,P05198,Q14232
Endosomal sorting complex required for transport escrt 0.4444752010757534 0.5276264977474019 0.5977585979795867 1.0 1.0 6
Formation of xylulose 5 phosphate -0.5653206985087745 -0.5265966173365346 0.5984737415261174 1.0 1.0 3 Q7Z4W1
Loss of mecp2 binding ability to the ncor smrt complex -0.7535819490957983 -0.5260903123832488 0.5988254593017952 1.0 1.0 2 O75376
Nrage signals death through jnk 0.4544060993990289 0.5257237307427778 0.5990801731622479 1.0 1.0 8 Q92974
Wnt5a dependent internalization of fzd4 -0.45234431677940606 -0.5229522843505499 0.601007458764758 1.0 1.0 9 P09497,P09496
Transport of vitamins nucleosides and related molecules -0.4425249480452796 -0.5227489482741442 0.6011489704679229 1.0 1.0 7 P12235,P36404
Mtorc1 mediated signalling -0.46069557342480066 -0.5195716748957904 0.6033621445172994 1.0 1.0 11 P62942,Q9Y2Q5
Map2k and mapk activation -0.4605616864779513 -0.5190555633811124 0.6037219948410328 1.0 1.0 11 Q02750,Q9Y2Q5
Synthesis of ip2 ip and ins in the cytosol 0.4622232300296736 0.5164502477318783 0.6055399789288489 1.0 1.0 5
Metabolism of steroid hormones 0.4465957491761402 0.5150071933819843 0.6065479933443703 1.0 1.0 7 O95772
Oxidative stress induced senescence -0.4718854191008777 -0.5133086980468317 0.6077354005657636 1.0 1.0 14 Q99496,P84243,P04637
Mecp2 regulates transcription factors 0.6619932947272125 0.5113169009802314 0.6091291723735448 1.0 1.0 1
G alpha i signalling events -0.5103061509204677 -0.5106978412699652 0.6095626525644182 1.0 1.0 26 P07602,P62136,P62879,P62873,P08754,P04899,Q00535
Pregnenolone biosynthesis -0.4642654779978533 -0.5103346375592729 0.6098170401652163 1.0 1.0 5 P15121,P22570
Beta oxidation of decanoyl coa to octanoyl coa coa 0.43988345008405977 0.5092317644318938 0.6105897805525913 1.0 1.0 6
Metabolism of ingested semet sec mesec into h2se -0.7478678581116779 -0.5090160000850928 0.6107410090479366 1.0 1.0 2 P23526
Diseases of base excision repair 0.661078939347755 0.5077339697912409 0.6116399220889914 1.0 1.0 1
G alpha q signalling events -0.45938483653456985 -0.49771305023722956 0.6186863085044847 1.0 1.0 12 P62879,P62873
Protein protein interactions at synapses 0.4747871441676838 0.49576600109814045 0.6200595148651951 1.0 1.0 14 Q14168,P41440
Estrogen biosynthesis 0.6574215178299248 0.49351087837391044 0.6216516552881473 1.0 1.0 1
Tyrosine catabolism -0.7416363719050325 -0.4906134860965928 0.6236998461649661 1.0 1.0 2 P16930
Gluconeogenesis -0.4874481647792496 -0.4889708495545669 0.6248623346773359 1.0 1.0 20 P04075,P00505,P40926,P40925,P11498,P60174,P04406
Rna polymerase iii transcription termination 0.4343711843711863 0.4874117322287823 0.625966581005474 1.0 1.0 6 Q9BUI4,O15160,O14802,P05455,Q9NVU0
Signaling by notch2 -0.7400251264519689 -0.48589326793636156 0.627042841724494 1.0 1.0 2 Q92542
Notch2 activation and transmission of signal to the nucleus -0.7400251264519689 -0.48589326793636156 0.627042841724494 1.0 1.0 2 Q92542
Methylation -0.4321138159212941 -0.482760262435231 0.6292659690158284 1.0 1.0 7 P23526,P31153,P78417
Cd28 dependent pi3k akt signaling 0.7274752240806059 0.4798608991694426 0.6313263060742329 1.0 1.0 2
Dap12 signaling 0.5404612136226341 0.4764996912392003 0.6337184272637317 1.0 1.0 3 P19174
Plasma lipoprotein remodeling -0.7364268511493703 -0.4754096965461982 0.6344949844454053 1.0 1.0 2 P07237
Dag and ip3 signaling 0.44128318241972875 0.4739027563965102 0.6355692535325268 1.0 1.0 8 P19174,Q13557,P52292,O43865
Deubiquitination 0.3311072052874278 0.4736029239529895 0.6357830900026691 1.0 1.0 99 P49721,Q96K76,O00231,P20618,O43242,P28072,Q969V5,P51665,P60900,O14964,Q96FW1,P21796,P45880,P28070,P28074
Ercc6 csb and ehmt2 g9a positively regulate rrna expression -0.45280779762361595 -0.4730074910423574 0.6362078347729665 1.0 1.0 12 P84243,Q92769
Apoptotic cleavage of cell adhesion proteins 0.43030852846067547 0.47152196224495946 0.6372680398849648 1.0 1.0 6
Inactivation of cdc42 and rac1 0.5378929839032007 0.46846201152086653 0.6394542312391045 1.0 1.0 3
Diseases associated with glycosylation precursor biosynthesis 0.4433937841642791 0.4628034358576118 0.6435052682350735 1.0 1.0 9
Gpvi mediated activation cascade -0.4209144896064772 -0.45964713618490316 0.6457695198469136 1.0 1.0 6 Q06124,P61586
Eph ephrin mediated repulsion of cells -0.4528032453526061 -0.45726795850939617 0.6474784571432604 1.0 1.0 13 Q92542,P09497,Q15375,P07947,P09496
Josephin domain dubs -0.7295348124971289 -0.4555578975100035 0.648707924721561 1.0 1.0 2 P55072
Ldl clearance -0.45611509309389103 -0.4543045518353619 0.6496096403299494 1.0 1.0 14 P38571,P01130
Telomere c strand synthesis initiation -0.5434601768651882 -0.45426489283921634 0.6496381812587144 1.0 1.0 3 P09884
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.5324194721459217 0.4515106302300236 0.6516215652752995 1.0 1.0 3
Synthesis secretion and deacylation of ghrelin 0.5324194721459217 0.4515106302300236 0.6516215652752995 1.0 1.0 3
Release of apoptotic factors from the mitochondria -0.6555928070710164 -0.45128274535321583 0.6517857791571726 1.0 1.0 1 Q9NR28
Vitamin d calciferol metabolism 0.5320874426475536 0.45049032229497454 0.6523569307762618 1.0 1.0 3 P04062
Bile acid and bile salt metabolism -0.41736632168342647 -0.4464861290936589 0.6552461300093062 1.0 1.0 6 P22307,Q9H4L5
Synthesis of bile acids and bile salts -0.41736632168342647 -0.4464861290936589 0.6552461300093062 1.0 1.0 6 P22307,Q9H4L5
Transcriptional regulation by mecp2 -0.4575741025025921 -0.4451071369829477 0.6562423313850292 1.0 1.0 15 Q9NWH9,P18031,O75376,Q92769
Interleukin 3 interleukin 5 and gm csf signaling -0.4217780645314546 -0.4442124389569365 0.6568889998325704 1.0 1.0 7 P07947,P46109,Q06124
Grb2 events in erbb2 signaling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Signaling by fgfr3 fusions in cancer 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Interleukin receptor shc signaling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Egfr transactivation by gastrin 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Activated ntrk3 signals through ras 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Activated ntrk2 signals through pi3k 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Activated ntrk2 signals through ras 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Sos mediated signalling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc related events triggered by igf1r 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Pi3k events in erbb2 signaling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc mediated cascade fgfr3 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc1 events in erbb2 signaling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc1 events in egfr signaling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc mediated cascade fgfr4 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc1 events in erbb4 signaling 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Shc mediated cascade fgfr1 0.6443157573910331 0.44402832339848514 0.657022106495706 1.0 1.0 1
Ptk6 regulates proteins involved in rna processing 0.7140243902439023 0.4429571797933168 0.6577967073307995 1.0 1.0 2 P23246
Scavenging by class f receptors -0.4765696482123368 -0.4426088293093796 0.6580486973195225 1.0 1.0 4 P27797
Diseases of immune system 0.712701607854935 0.4393962242602587 0.6603744618991729 1.0 1.0 2
Condensation of prometaphase chromosomes 0.4420459134758297 0.43918719502884773 0.6605259026020529 1.0 1.0 10 P67870,P68400,Q15021,P19784,O95347,P06493
Mitochondrial trna aminoacylation -0.4628029064669694 -0.43664030362548756 0.6623722286804374 1.0 1.0 17 Q9H2U2,Q15046,P26640,Q5ST30,Q5JTZ9,Q6PI48,P41250,P49590,Q9NP81
Rho gtpases activate pkns -0.4695952173553194 -0.4357040628314937 0.6630514576136188 1.0 1.0 19 Q7Z406,P60660,P61981,P61586,Q04917,P27348,Q9Y3B8,P62258,P62140,P84243,P63104
Activation of ampk downstream of nmdars -0.4439759377824304 -0.4353218166406608 0.6633288513039064 1.0 1.0 5 Q9BVA1
Rna polymerase i transcription termination -0.43295016398704683 -0.4328448509399691 0.6651274872553015 1.0 1.0 10 Q3B726,O15446
Ptk6 regulates rho gtpases ras gtpase and map kinases -0.5365001824753618 -0.43197948626491417 0.66575632262431 1.0 1.0 3 P61586
Nade modulates death signalling -0.7207317073170335 -0.43065409795275733 0.6667198994892487 1.0 1.0 2 P62258,P42574
Regulation of signaling by cbl -0.47302244076117544 -0.43004720818566694 0.6671613010211217 1.0 1.0 4 P07947,P46109
Robo receptors bind akap5 -0.719402789317966 -0.4269401598575419 0.6694229135907532 1.0 1.0 2 P13861
Fatty acyl coa biosynthesis 0.4683091730052277 0.4244220644851909 0.6712580320548911 1.0 1.0 17 P50897,Q9UMR5,Q4G176
Regulation of runx1 expression and activity 0.5227986772907738 0.4223291427678341 0.6727847893744598 1.0 1.0 3
Signaling by alk -0.4403266581310087 -0.4222671160980238 0.6728300575945463 1.0 1.0 5 Q92769
Intraflagellar transport -0.43304382931061985 -0.41709552068645744 0.676608541159706 1.0 1.0 11 Q9BVA1,P63167,Q9BW83
Pexophagy 0.7041650224890813 0.4167212084525773 0.6768823397185695 1.0 1.0 2
Rna polymerase iii transcription initiation from type 3 promoter 0.43423863289592335 0.4155972975797987 0.6777047045040161 1.0 1.0 5 Q9NVU0,O15160,O14802,Q9BUI4
Rna polymerase iii chain elongation 0.43423863289592335 0.4155972975797987 0.6777047045040161 1.0 1.0 5 Q9NVU0,O15160,O14802,Q9BUI4
Mitochondrial translation -0.5019867932188484 -0.41401162095289384 0.6788655961858756 1.0 1.0 54 Q9Y2Q9,P82650,Q9Y3B7,Q8N5N7,Q9H9J2,Q8N983,Q96DV4,Q9BYD6,Q9HD33,P51398,P46199,Q7Z2W9,Q9NWU5,P49406,Q9H2W6,Q9Y3D3,P43897,Q9BYD3,P49411,Q6P1L8,Q9Y2R5,Q96EL3,Q9Y3D9
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain -0.46834340789209533 -0.41365735305643536 0.6791250639698303 1.0 1.0 4 Q92597,P04637
The citric acid tca cycle and respiratory electron transport -0.3595079533720081 -0.4113668896237491 0.680803528676112 1.0 1.0 92 O14548,P21912,P36957,P07954,Q8NCN5,O75947,Q9BU61,O75251,O95182,P13804,P31040,Q9P2R7,P40926,P10515,P19404,P25705,Q99798,P50213,P09622,P38117,Q86Y39,P10606,Q96I99,Q04760,O95299,O75390,Q02218,P08559,P14854,P49821
Metabolism of amino acids and derivatives -0.2937662436313608 -0.41060910055643923 0.6813591895299429 1.0 1.0 195 P63173,P27635,P36957,P05388,P61457,P41252,P61289,P31937,P24752,P83881,P30050,Q92947,Q99714,P23526,P25398,P04181,O75832,P56192,P00505,P25786,Q8TD30,P45954,Q96RQ3,P10515,O94925,P46776,P21953,P63220,P61247,P09622,P08865,P62263,Q15046,Q9Y617,O14818,P05386,P52758,P16930,P00390,P30038,P05387,P32969,Q6NVY1,P14868,P23378,P49419,Q9BV20,P57772,P62888,P25789,P26440,P62851,P30084,Q02252,Q02218,P18077,P08559,P12532,P49189,P62249,O43175
Cdt1 association with the cdc6 orc origin complex 0.5181700696493997 0.4081400452527921 0.6831708617092662 1.0 1.0 41 P49721,O00231,P20618,Q9Y619,P28072,P51665,P60900,P28070,P28074
Galactose catabolism -0.5287851654990581 -0.4077357331279762 0.6834677004844194 1.0 1.0 3 Q14376,P51570
Mapk1 erk2 activation -0.5264872589081315 -0.4006118602215774 0.6887059122518229 1.0 1.0 3 P36507,Q06124
Synthesis of pips at the plasma membrane -0.42325677180022775 -0.3984719078448992 0.6902823618099152 1.0 1.0 10 Q13496,Q13614
Signaling by erbb4 -0.4078170526485161 -0.39415615934040044 0.6934657508391304 1.0 1.0 7 Q15334,O75376,Q92542
Caspase activation via death receptors in the presence of ligand -0.52436558067533 -0.39407499681022284 0.6935256701472456 1.0 1.0 3 Q12933
Regulation by c flip -0.52436558067533 -0.39407499681022284 0.6935256701472456 1.0 1.0 3 Q12933
Phenylalanine metabolism -0.52389334738874 -0.3926254236638005 0.6945961591015313 1.0 1.0 3 P09417,P61457
Synthesis of active ubiquitin roles of e1 and e2 enzymes -0.41680785562481426 -0.39206851745301335 0.6950075884886817 1.0 1.0 9 A0AVT1,P45974,P60604
Nrcam interactions -0.7060393720677133 -0.39028623842964555 0.696324898201242 1.0 1.0 2 Q15334
Ionotropic activity of kainate receptors -0.7060393720677133 -0.39028623842964555 0.696324898201242 1.0 1.0 2 Q15334
Toll like receptor tlr1 tlr2 cascade 0.46262781219035626 0.38961678397115046 0.696819939247387 1.0 1.0 18 Q8IV63,P63208,Q14738,Q15750,P51812,Q15418,Q9Y6K9,P61088
Lrr flii interacting protein 1 lrrfip1 activates type i ifn production -0.7039634146341097 -0.3847086504572504 0.7004532854373042 1.0 1.0 2 Q32MZ4,P35222
Inla mediated entry of listeria monocytogenes into host cells -0.7039634146341097 -0.3847086504572504 0.7004532854373042 1.0 1.0 2 O60716,P35222
Asparagine n linked glycosylation 0.24753332536642286 0.3837663756626451 0.7011516116371761 1.0 1.0 127 O15498,Q9Y5P6,Q9NYU2,Q15436,Q9BV10,P61923,P04844,P04066,Q9Y6G9,O95249,Q9UKM7,O15027,Q96PC5,Q9Y296,P83436,O43731,P16278,Q8N6H7,Q13561,O95486,P24390,Q14789,O75935,Q13190,Q12893,P61803,Q9UP83,Q9H0U4,Q9NZ32,P10619,O60763,Q9BUN8,Q14203,Q14204
Mapk3 erk1 activation -0.5197383496699215 -0.379956762638605 0.703977510844163 1.0 1.0 3 Q02750,Q06124
Gp1b ix v activation signalling -0.7021341463414271 -0.37982057727846863 0.7040786065697291 1.0 1.0 2 P21333,P63104
Notch4 activation and transmission of signal to the nucleus -0.7021341463414271 -0.37982057727846863 0.7040786065697291 1.0 1.0 2 Q92542,P63104
Defective lfng causes scdo3 0.626028649801882 0.37914387994039883 0.7045810230208307 1.0 1.0 1
Notch2 intracellular domain regulates transcription 0.626028649801882 0.37914387994039883 0.7045810230208307 1.0 1.0 1
Degradation of axin 0.50645657925991 0.37302677413655416 0.7091285169614594 1.0 1.0 38 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Regulation of tnfr1 signaling -0.4015321597938167 -0.37244059483716335 0.7095648340078398 1.0 1.0 7 Q6GQQ9,Q12933,P63244
Rmts methylate histone arginines -0.45128013631753006 -0.37230680672719824 0.7096644312863183 1.0 1.0 19 Q92922,Q68CP9,Q99873,Q12824,O14497,O96019,Q9BQA1,P61964
Parasite infection 0.4646251433766405 0.3709422136907391 0.7106805726069405 1.0 1.0 20 Q7L576,O15143,P07948,P35579,Q9UQB8
Regulation of runx3 expression and activity 0.5053639401582608 0.36892137850790513 0.712186327882302 1.0 1.0 38 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
B wich complex positively regulates rrna expression -0.44650560979580356 -0.36790933578697577 0.7129408387908558 1.0 1.0 18 Q9NY93,Q9GZS1,Q3B726,P35659,Q9H9Y6,Q9BQG0,P84243,O15446
Asymmetric localization of pcp proteins 0.5058793285872785 0.36696267662953097 0.7136468584732898 1.0 1.0 39 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Raf independent mapk1 3 activation -0.3949167673744362 -0.3668038733146344 0.7137653182423083 1.0 1.0 6 Q02750,Q06124
Abacavir metabolism 0.6223712282840518 0.36678690539783626 0.7137779759145457 1.0 1.0 1
Cd163 mediating an anti inflammatory response 0.6838414634146446 0.3649717396180393 0.7151325017977481 1.0 1.0 2 P35579
P38mapk events 0.6838414634146377 0.36497173961802293 0.7151325017977603 1.0 1.0 2 P11233
Activation of ppargc1a pgc 1alpha by phosphorylation 0.6838414634146339 0.3649717396180137 0.7151325017977672 1.0 1.0 2 P54619
Inactivation of csf3 g csf signaling 0.4014152418966762 0.3638237004906715 0.7159896633500298 1.0 1.0 6 Q93034,P07948
Tp53 regulates transcription of death receptors and ligands -0.6958491329412148 -0.3632200528985217 0.7164405090389177 1.0 1.0 2 P04637
G0 and early g1 0.4184488078346255 0.36249949357922634 0.716978801900177 1.0 1.0 5 P24941
P75ntr negatively regulates cell cycle via sc1 -0.6954268292682576 -0.36211554774137017 0.7172656855601549 1.0 1.0 2 Q13547,Q92769
Coenzyme a biosynthesis -0.5125247018218221 -0.3583366600814515 0.7200913863557112 1.0 1.0 3 Q96CD2
Piwi interacting rna pirna biogenesis 0.4147617319179904 0.35729455506012125 0.7208713057774219 1.0 1.0 9
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.4097451637625926 0.35702416541922494 0.7210737149536608 1.0 1.0 8
Insulin processing 0.4096490512201011 0.3566867610267928 0.7213263176592692 1.0 1.0 8 Q9UPT5,Q8TAG9,Q96KP1
Vegfr2 mediated cell proliferation 0.6801829268292955 0.35600675266976617 0.7218355081608088 1.0 1.0 2 O43865
Erythropoietin activates phospholipase c gamma plcg 0.6801829268292867 0.3560067526697457 0.7218355081608241 1.0 1.0 2 P07948
Signaling by notch3 0.3991708578774684 0.35588909836898946 0.7219236202596426 1.0 1.0 6
Caspase activation via extrinsic apoptotic signalling pathway -0.45104919166950647 -0.3549810972448318 0.7226037524518798 1.0 1.0 4 Q12933,P42574
Cytochrome c mediated apoptotic response -0.45069412271168696 -0.3538096236941786 0.7234815607600322 1.0 1.0 4 Q96GX9,P42574,Q9NR28
Netrin 1 signaling 0.40862685479478134 0.35310601190984614 0.7240089659825051 1.0 1.0 8 O94813,P19174,P15311,Q16539
Rac3 gtpase cycle 0.4937408518735686 0.35276198069965087 0.7242668886549353 1.0 1.0 33 O15498,Q13017,P50402,Q6IAA8,Q8TAA9,Q68EM7,Q7L576,Q14739,Q9NSV4,P02786,O15173,Q9UQB8
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.6786585365853657 0.3523040467335728 0.7246102536035548 1.0 1.0 2 O00767
Nef mediated downregulation of mhc class i complex cell surface expression -0.5083867032631761 -0.3461561418631488 0.7292253732237333 1.0 1.0 3 O43747,Q10567,P04439
Dna replication 0.3568906207608923 0.3460678828177088 0.7292916996280452 1.0 1.0 93 P49721,O00231,P20618,O43242,Q9Y619,P28072,P18858,Q9Y248,P51665,P60900,P41440,P28070,P28074
Vitamin b5 pantothenate metabolism -0.38785649195830973 -0.3431391325384384 0.7314937928000276 1.0 1.0 6 Q96CD2
Nuclear signaling by erbb4 -0.4472205322320591 -0.3424234496954065 0.7320322436573179 1.0 1.0 4 O75376,Q92542
Tp53 regulates transcription of cell cycle genes -0.4272009210463585 -0.34111843979686984 0.7330144199340913 1.0 1.0 15 P04637,Q9C0C2,Q99873,Q9Y3B8,P12004,Q9UIV1
Sensory perception -0.46234170704856614 -0.34107163858473694 0.733049651584476 1.0 1.0 26 Q14651,P62873,P01130,Q6IBS0,P23634
Pyruvate metabolism -0.4270072776781385 -0.3404963533274079 0.7334827685356833 1.0 1.0 15 Q8NCN5,Q04760,P10515,P08559,P09622
Metabolism of polyamines 0.4990501913728878 0.3382046609497698 0.7352089636742474 1.0 1.0 40 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Ub specific processing proteases 0.42641811292802545 0.33799534377909307 0.7353666966386712 1.0 1.0 80 P49721,Q96K76,O00231,P20618,O43242,P28072,Q969V5,P51665,P60900,O14964,P21796,P45880,P28070,P28074
Toll like receptor 9 tlr9 cascade 0.45084096544254687 0.33524717375508845 0.7374386393535508 1.0 1.0 19 Q8IV63,P05067,P63208,P30154,Q14738,Q16539,Q15750,P51812,Q15418,Q9Y6K9,P61088
Scf skp2 mediated degradation of p27 p21 0.49972771272094013 0.3352062062422572 0.7374695406939968 1.0 1.0 42 P49721,O00231,P11802,P20618,O43242,P28072,P51665,P60900,P28070,P28074
Wax and plasmalogen biosynthesis 0.425818787094521 0.33382232458798233 0.7385136362596225 1.0 1.0 4 Q6IAN0
Fcgr3a mediated il10 synthesis 0.3973764983188548 0.33169543697389114 0.7401192465707169 1.0 1.0 7 O43865
Cellular response to hypoxia 0.498335228049435 0.33009339785322794 0.7413293916620654 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,Q9Y241,P28074
Association of tric cct with target proteins during biosynthesis -0.43468640100237094 -0.32966808525252267 0.7416507710819191 1.0 1.0 18 P50991,P40227,P04637,P78371,P48643,P17987,Q9H0D6,P49368,Q99832,O00567
Regulation of pten gene transcription -0.44134539309449156 -0.32933612295708786 0.7419016434257542 1.0 1.0 20 Q99496,Q9Y2Q5,P04637,Q92769
Synthesis of dna 0.3895977311932739 0.32796956588091675 0.7429346739362708 1.0 1.0 87 P49721,O00231,P20618,O43242,Q9Y619,P28072,P18858,Q9Y248,P51665,P60900,P41440,P28070,P28074
Degradation of dvl 0.4951867571613886 0.3276505825831246 0.743175871813655 1.0 1.0 39 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Sealing of the nuclear envelope ne by escrt iii -0.3820463080097825 -0.32420823291228423 0.7457803894735542 1.0 1.0 6 Q9BVA1
Signaling by flt3 fusion proteins 0.4060913118744436 0.3231410677436985 0.7465884096279258 1.0 1.0 5 Q01082,Q14789
Suppression of phagosomal maturation 0.39482170651031134 0.323013072524333 0.7466853418666597 1.0 1.0 7 O14964
Rnd2 gtpase cycle 0.4355056296423775 0.32199542128540404 0.7474561632347312 1.0 1.0 16 P51648,Q13017,Q8TAA9,P02786,P38159,Q07065
Sulfur amino acid metabolism 0.4092081569004773 0.3217167569406243 0.747667282025748 1.0 1.0 10 Q9UBX3,Q13126
Regulation of mecp2 expression and activity 0.4136581252158719 0.3209502254414426 0.7482481112685446 1.0 1.0 11 Q14739,Q9HCE1
Signaling by erbb2 in cancer 0.4052244991694611 0.3204574035442215 0.7486216161281536 1.0 1.0 5 P19174,Q16543,P07900
Signaling by erbb2 ecd mutants 0.4052244991694611 0.3204574035442215 0.7486216161281536 1.0 1.0 5 P19174,Q16543,P07900
Rho gtpases activate cit -0.39974235943612996 -0.32034454476929214 0.7487071589860637 1.0 1.0 10 O43663,Q15334,P60660,P61586
Runx1 interacts with co factors whose precise effect on runx1 targets is not known -0.4236945410309238 -0.3180014241447038 0.7504838566319432 1.0 1.0 16 Q92922,Q68CP9,Q99496,Q9HC52,Q12824,O14497,O96019
Akt phosphorylates targets in the nucleus 0.6071319719597592 0.31765730128264946 0.750744903416324 1.0 1.0 1
Regulation of gene expression in beta cells 0.6071319719597592 0.31765730128264946 0.750744903416324 1.0 1.0 1
Runx2 regulates genes involved in cell migration 0.6071319719597592 0.31765730128264946 0.750744903416324 1.0 1.0 1
Transcriptional regulation by the ap 2 tfap2 family of transcription factors -0.3798720805882734 -0.3172544839439127 0.7510505112604271 1.0 1.0 6 P10809,P06748,P35659
Nuclear receptor transcription pathway -0.4973682788192716 -0.3145459730274592 0.7531064054901091 1.0 1.0 3 O75376
Formation of the beta catenin tcf transactivating complex -0.4020955261227308 -0.31387133431010855 0.7536187628782631 1.0 1.0 11 Q15291,P35222,Q13547,Q9Y265,P84243
Maturation of protein 3a 0.6056080463273299 0.3129594114836195 0.7543114991625015 1.0 1.0 1
Mastl facilitates mitotic progression 0.40276093946965946 0.3128871623820273 0.7543663911860614 1.0 1.0 5 P06493,P30154,P30153
Hiv transcription elongation -0.44217464472362433 -0.312497039217173 0.7546628128447552 1.0 1.0 22 P55199,Q15370,Q09161,P19387
Retrograde transport at the trans golgi network -0.41000807561226527 -0.3121468792455365 0.754928900624003 1.0 1.0 13 Q99747,P20645,Q96JB2,Q96MW5
Collagen formation 0.4154877772431478 0.3118760515821089 0.7551347234555281 1.0 1.0 12 Q32P28,P07858
Cyclin a cdk2 associated events at s phase entry 0.4941461035379874 0.3111716611553608 0.7556701254509359 1.0 1.0 44 P49721,O00231,P11802,P20618,O43242,P28072,P51665,P60900,P28070,P28074
Map3k8 tpl2 dependent mapk1 3 activation -0.4373469448838308 -0.3108174254847387 0.755939421752847 1.0 1.0 4 Q02750
G protein mediated events -0.40083471543022864 -0.3099603196209173 0.7565911315933322 1.0 1.0 11 P13861,P63096,P08754,P04899
Rho gtpases activate wasps and waves 0.4277706518120529 0.30977420726241567 0.7567326670630241 1.0 1.0 15 Q7L576,Q9UQB8
Rap1 signalling -0.4955315189479095 -0.3093968138449315 0.7570196937618932 1.0 1.0 3 P63104
Glycerophospholipid biosynthesis 0.48100833305333623 0.30809442122896136 0.7580104861162194 1.0 1.0 33 P35790,P68400,Q8N2A8,Q9HCL2,Q9NPH0,Q8IV08,Q96N66,Q9NQZ5,Q8NCC3
Vxpx cargo targeting to cilium 0.3950948748649931 0.3070753109784056 0.758786049417326 1.0 1.0 8 Q9UPT5,Q8TAG9,Q96KP1
Influenza infection -0.22687950029140044 -0.30563885594070084 0.7598796325003221 1.0 1.0 125 P63173,P27635,P05388,P83881,P30050,P25398,P78406,P47914,P37198,P46776,P63220,P61247,P08865,P62263,P27797,Q9UKX7,Q14974,O00629,P05387,P32969,P27824,P52948,Q12849,Q9BVL2,P62888,P62851,Q86U42,Q8NFH5,P18077,P62249,P05386,P09496,P19387
The phototransduction cascade -0.40544597333815374 -0.30536912639544744 0.7600850330704174 1.0 1.0 5 P62873
Trna aminoacylation -0.46971066407774587 -0.3052894135227265 0.7601457381120622 1.0 1.0 36 Q13155,P41252,P56192,Q5ST30,Q6PI48,P41250,Q9NSD9,P54136,P49588,P49591,Q15046,Q15181,P23381,P14868,Q9NP81,Q9H2U2,P26640,P26639,Q5JTZ9,P07814,P49590,Q12904
Notch3 activation and transmission of signal to the nucleus 0.4799244237389919 0.3030069553139083 0.7618845610558931 1.0 1.0 3
Protein repair -0.6141420298689482 -0.30091007119516755 0.7634830703421991 1.0 1.0 1 P22061
Rhoa gtpase cycle 0.49153958670890746 0.29955381713442664 0.76451751580652 1.0 1.0 47 Q96HY6,O14578,Q13017,Q13464,P51572,P46940,Q8TAA9,P28288,Q15904,Q14739,Q9NSV4,P02786,P41440,Q8NBN3,O15173,Q14155,P30519,Q92974
Dex h box helicases activate type i ifn and inflammatory cytokines production -0.6704664499054984 -0.29939561051119334 0.7646382109649603 1.0 1.0 2 Q08211
Caspase mediated cleavage of cytoskeletal proteins 0.3877053644302856 0.29932945926270843 0.7646886791655914 1.0 1.0 7 P35611,P08670,P55212
Signaling by mras complex mutants 0.4774373527495119 0.2966782449192807 0.7667121676823978 1.0 1.0 3
Metabolism of folate and pterines 0.4012393568835685 0.29541730404940786 0.7676751161402948 1.0 1.0 10 P41440
Nef mediated cd8 down regulation -0.3724053724053712 -0.2939317893211636 0.7688100261369659 1.0 1.0 6 O94973,Q96CW1,O95782,Q9UI12,P63010,P53680
Nef mediated cd4 down regulation -0.3724053724053712 -0.2939317893211636 0.7688100261369659 1.0 1.0 6 O94973,Q96CW1,O95782,Q9UI12,P63010,P53680
Trafficking of glur2 containing ampa receptors -0.3724053724053712 -0.2939317893211636 0.7688100261369659 1.0 1.0 6 O94973,Q96CW1,O95782,P63010,P53680,P46459
Traf6 mediated nf kb activation -0.3716768685955642 -0.29170345795239894 0.7705133650956537 1.0 1.0 6 Q12933
Darpp 32 events -0.3857906225086422 -0.29128287340821607 0.770834984870163 1.0 1.0 9 P13861,Q00535,P62136
Mitochondrial fatty acid beta oxidation -0.42147271166926387 -0.2894213611854274 0.7722589502767097 1.0 1.0 18 Q9NPJ3,P05165,P30084,Q9BV79,P11310,P16219,P55084
Energy dependent regulation of mtor by lkb1 ampk -0.3755400034816596 -0.2886535048435354 0.7728465464705558 1.0 1.0 7 Q9Y2Q5
Role of lat2 ntal lab on calcium mobilization 0.6501902743363068 0.28683974641764765 0.7742350278708268 1.0 1.0 2
Rna polymerase i transcription -0.43347651699535483 -0.28653186170988093 0.7744707938397888 1.0 1.0 22 Q3B726,P84243,Q92769,O15446
Alk mutants bind tkis -0.3748298009872589 -0.28650990692225997 0.7744876067451765 1.0 1.0 7 Q9NR09,P06748,Q9HC35,O00291
Regulation of hmox1 expression and activity 0.48737923233397595 0.28529278243894624 0.7754198419756166 1.0 1.0 49 P49721,P09601,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Circadian clock -0.39625050503831755 -0.28320365086099863 0.7770207298911771 1.0 1.0 12 O75376,P62136,P50416,Q7Z5J4,Q9BWF3
Na cl dependent neurotransmitter transporters -0.6071319719597749 -0.2781799189737635 0.780874249061156 1.0 1.0 1 Q9H2J7
Degradation of cysteine and homocysteine 0.40550595160944647 0.2781054879432747 0.7809313830903348 1.0 1.0 4
Programmed cell death 0.30732694059046456 0.2776056669194191 0.7813150815024321 1.0 1.0 99 P49721,Q16625,O00231,Q13464,P20618,P51572,P28072,P51665,P41440,P28070,P28074
Hats acetylate histones -0.43870404680213365 -0.2772005536184193 0.7816261145540364 1.0 1.0 25 Q9ULM3,Q9UPT9,O95696,P51610,Q6IA86,P61964,Q01658,Q96L91,Q15393,O15294,Q96EB1,O75528,Q15014,Q96ES7,O96019,Q9H9T3,Q8WYH8,Q9Y265
Signaling by fgfr4 in disease 0.644512195121951 0.27465295019068214 0.7835828817003214 1.0 1.0 2 P19174
Cdc42 gtpase cycle 0.468225291004968 0.27208404239533635 0.7855573991747773 1.0 1.0 32 O15498,Q14155,Q13017,Q6IAA8,P46940,Q8TAA9,Q68EM7,Q14739,Q9NSV4,P02786,Q8N6H7,Q9UQB8
Signaling by nuclear receptors -0.45871861790726 -0.27005794615408285 0.787115674508994 1.0 1.0 56 O75376,P62873,P50416,P62879,P08754,P04899,P10515,Q15185,P08559,P17844,P09622,P84243,P19387
Transcriptional regulation of granulopoiesis -0.3682351629454006 -0.26699904325071294 0.7894698977350219 1.0 1.0 7 P84243
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux -0.39258335877246336 -0.26632159095617997 0.7899915461902207 1.0 1.0 5 O75376
Hedgehog on state 0.48004593503954973 0.2660464984116965 0.7902033984699466 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function -0.3902716020345642 -0.26589709069913536 0.7903184657548836 1.0 1.0 12 Q15291,Q99873,Q03164,P61964,P84243
Rac2 gtpase cycle 0.4680622597927961 0.2653282332778878 0.7907566166746365 1.0 1.0 33 P50402,Q6IAA8,P46940,Q8TAA9,Q68EM7,Q7L576,Q9NSV4,Q86XL3,P02786,Q13505,O15173,Q14739
Smac xiap regulated apoptotic response -0.6557926829268014 -0.2650081669210624 0.7910031703933587 1.0 1.0 2 P42574,Q9NR28
Toll like receptor cascades 0.44585192928548234 0.26489849840683966 0.7910876551245112 1.0 1.0 24 P05067,Q8IV63,P07858,P63208,P30154,P50570,Q14738,Q16539,Q13546,Q15750,P51812,Q15418,Q9Y6K9,P61088
Auf1 hnrnp d0 binds and destabilizes mrna 0.47923189417865203 0.2633351282496114 0.7922922864369228 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Defective ripk1 mediated regulated necrosis -0.654223476590907 -0.2614453186321588 0.7937491127137153 1.0 1.0 2 Q12933
Wnt ligand biogenesis and trafficking 0.37025551569087245 0.2601392596294447 0.7947563552953589 1.0 1.0 6 O75436
Signaling by hippo -0.36098007287254186 -0.2599836972785495 0.7948763490002022 1.0 1.0 6 Q07157,P62258,Q4VCS5,P42574
Mtor signalling -0.4001762632946144 -0.2599005763219338 0.7949404667058808 1.0 1.0 15 P62942,Q9Y2Q5
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.39826071540212615 0.2596174219790608 0.7951588962271918 1.0 1.0 4 Q9Y6K9
Glutamate neurotransmitter release cycle -0.47682767782131014 -0.25903017132409484 0.7956119613875758 1.0 1.0 3 O94925
Degradation of gli1 by the proteasome 0.47782663138466275 0.2586834564317946 0.7958794850510029 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Formyl peptide receptors bind formyl peptides and many other ligands 0.46079297419508103 0.2561604836991163 0.797826920254292 1.0 1.0 3
Mapk6 mapk4 signaling 0.47901231261646776 0.2558896446604895 0.7980360508504392 1.0 1.0 49 P49721,O00231,P20618,P28072,P51665,P60900,P28070,Q9HCE1,P28074
Cd28 dependent vav1 pathway 0.38297223069878894 0.2552701013581393 0.7985144907944515 1.0 1.0 5 Q13177,Q16512,P63000,P62993
Cross presentation of soluble exogenous antigens endosomes 0.47389279654915745 0.2550100685827841 0.7987153226654573 1.0 1.0 39 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Transcriptional regulation by runx3 0.4764473113014777 0.2541534665968975 0.7993769987011454 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Apoptotic factor mediated response -0.3586691086691075 -0.25338234522491176 0.7999727690855847 1.0 1.0 6 P28482,Q9NR28,P42771,P42574,Q07021,Q96GX9
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters -0.37274671555148453 -0.2533435439798597 0.8000027501078859 1.0 1.0 9 Q10567,O94973,Q96CW1,O95782,P04439,P63010,Q9UI12,P53680,O43747
G2 m checkpoints 0.3814752337940065 0.25215769498580204 0.8009191761815082 1.0 1.0 86 P49721,Q9NYZ3,O00231,P20618,O43242,Q9Y619,P28072,P24941,P51665,P60900,Q9UQ84,P28070,P28074
Translation -0.28885278755029564 -0.25082184564910737 0.8019518509741683 1.0 1.0 220 Q9Y3B7,P60468,O15371,Q96DV4,Q9HD33,P61619,P47914,Q5ST30,Q6PI48,P63220,Q9NSD9,P08865,Q15046,O00303,Q9H2W6,P32969,P14868,P43897,Q9BYD3,P62888,Q6P1L8,P18077,Q96EL3,P60059,Q9Y2Q9,P05388,P41252,O75822,Q8N5N7,P25398,Q9H9J2,Q8N983,P13639,P46776,P56537,P46199,Q7Z2W9,Q9NWU5,Q15181,P05387,P23381,Q9H2U2,Q9Y2R5,P63173,P27635,Q13347,P82650,P56192,P15170,P51398,P13798,P24534,Q02543,P62829,P61247,P41091,P62263,P49588,P49406,Q9NP81,P49411,P06730,Q5JTZ9,P35268,P60842,Q13084,P62249,P05386,P49591,Q7Z7H8,P83881,Q9BYD2,P30050,Q9Y399,Q9BYD6,P08708,Q05639,P41250,P61009,P54136,Q9Y3D3,Q9UBQ5,P62851,P49458,P49590,Q9Y3D9,Q9BRJ2
Regulation of ras by gaps 0.4744753486528264 0.25039079383718177 0.8022851483701727 1.0 1.0 41 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
N glycan trimming in the er and calnexin calreticulin cycle -0.39602131352725917 -0.24846490765750276 0.8037747185239699 1.0 1.0 15 P27797,P55072,P30101,P14314,P27824
Amino acid transport across the plasma membrane 0.3932275777913459 0.24722169429435553 0.8047366566827052 1.0 1.0 4 P08195,P30825,Q15758
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.6307926829268289 0.24645640027138388 0.805328951178643 1.0 1.0 2 P52292
Phase 0 rapid depolarisation 0.6307926829268291 0.24645640027138388 0.805328951178643 1.0 1.0 2 Q13557
Hur elavl1 binds and stabilizes mrna 0.39280399407865796 0.24619546873321185 0.8055309230584322 1.0 1.0 4
Activated notch1 transmits signal to the nucleus -0.4710417215514781 -0.24424476944660953 0.8070412557645592 1.0 1.0 3 Q92542
Fbxw7 mutants and notch1 in cancer 0.6293547852899197 0.2436052115063361 0.8075365916803703 1.0 1.0 2
Myd88 independent tlr4 cascade 0.4219132220400523 0.2427791740218542 0.8081764696927409 1.0 1.0 19 Q8IV63,P05067,P63208,P30154,Q14738,Q13546,Q15750,P51812,Q15418,Q9Y6K9,P61088
Negative regulation of notch4 signaling 0.4716087523295192 0.24120404787483926 0.8093969737591005 1.0 1.0 41 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Vitamin c ascorbate metabolism -0.4698272325066999 -0.24119082436203163 0.8094072221126571 1.0 1.0 3 P00387,P78417
Insulin receptor signalling cascade -0.35429724316933653 -0.2411449652002459 0.8094427636710277 1.0 1.0 6 Q13322,Q06124
G1 s dna damage checkpoints 0.4719884991633016 0.23975507085143202 0.8105201393984216 1.0 1.0 42 P49721,O00231,P20618,O43242,P28072,P51665,P60900,P28070,P28074
E2f mediated regulation of dna replication 0.3878372349333161 0.23946536690530684 0.8107447485172232 1.0 1.0 11 P49642,Q9Y619,P06493
Stabilization of p53 0.46980106469342814 0.23549057010297902 0.8138279970553015 1.0 1.0 41 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Sema4d induced cell migration and growth cone collapse 0.3664576912750476 0.23329881170996827 0.815529381269642 1.0 1.0 7 P35580,Q13464
Defective cftr causes cystic fibrosis 0.4698732965950236 0.23078282474130646 0.8174835249583179 1.0 1.0 43 P49721,O00231,P20618,P28072,P51665,P60900,Q9BUN8,P28070,P28074
The role of nef in hiv 1 replication and disease pathogenesis -0.37297462549678656 -0.2300984191850018 0.8180152932482581 1.0 1.0 11 Q10567,O94973,P63000,Q96CW1,Q13177,O95782,P04439,P63010,Q9UI12,P53680,O43747
Synthesis of gdp mannose 0.38534759951484215 0.22856827044948194 0.8192044882473293 1.0 1.0 4
Cytoprotection by hmox1 0.4452278177067186 0.2283736453899112 0.8193557760639323 1.0 1.0 68 P49721,P09601,O00231,O75182,P13073,P20618,O43242,P28072,P51665,P60900,P28070,P30519,P28074
Signaling by leptin -0.6386471816954494 -0.22732067634929964 0.8201743965174921 1.0 1.0 2 Q06124
Interleukin 37 signaling -0.6386471816954494 -0.22732067634929964 0.8201743965174921 1.0 1.0 2 Q06124
Translesion synthesis by polk 0.3787115201832967 0.22641292501194682 0.8208802762170291 1.0 1.0 10
Fceri mediated nf kb activation 0.4685376503596268 0.22469609941487456 0.8222156992420617 1.0 1.0 44 P25787,P49721,O00231,Q15008,P20618,O43242,P63208,P28072,P28070,P51665,P60900,P07948,P61088,P28074
Hiv infection 0.23417334062281817 0.22054011837966625 0.825450531460501 1.0 1.0 129 P49721,O00231,Q8IXH7,Q93034,P20618,O43242,P18858,P28072,P51665,P60900,P29083,P28070,Q9BTX1,P28074
Abc transporter disorders 0.46703807380630846 0.22002343067320615 0.8258529067661673 1.0 1.0 44 P49721,O00231,P20618,P28072,P51665,P60900,Q9BUN8,P28070,P28074
Nucleotide salvage 0.36173622441582587 0.21963948942092434 0.8261519341811614 1.0 1.0 7 Q08623
Regulation of pten stability and activity 0.4656377051315831 0.2176154812551924 0.8277287212595947 1.0 1.0 43 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
The activation of arylsulfatases -0.6333812069608966 -0.21630471031733944 0.8287502376737717 1.0 1.0 2 P15289
Noncanonical activation of notch3 0.6143927149831929 0.21513120357705828 0.8296650264867862 1.0 1.0 2
P130cas linkage to mapk signaling for integrins 0.5699481865284853 0.21482129484748846 0.8299066495889582 1.0 1.0 1
Signaling by vegf 0.43160079197776396 0.21375705109881035 0.8307365190464346 1.0 1.0 25 Q96JJ3,Q13464,P42345,O43865,Q7L576,Q9UQB8
Maturation of sars cov 1 nucleoprotein 0.6134410732953325 0.21339454124049728 0.8310192379134294 1.0 1.0 2
Lysosome vesicle biogenesis -0.374498387808597 -0.212798735064826 0.831483950420588 1.0 1.0 13 P09497,Q8NBS9,P09496,P20645
Depolymerisation of the nuclear lamina 0.36428196083194025 0.2127583789610524 0.831515429209279 1.0 1.0 8 P50402,P06493,Q8NC56
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.39999168306095595 0.21271718741627924 0.8315475599419575 1.0 1.0 16 Q9BTY2,Q02818,Q15293,Q13217,O76024,Q07065
Striated muscle contraction -0.3433812843643172 -0.212058053733974 0.8320617437216644 1.0 1.0 6 P06753,P11532
Dectin 1 mediated noncanonical nf kb signaling 0.4627383406038994 0.2111047490291268 0.8328055345505199 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Hedgehog ligand biogenesis 0.4613311550340922 0.20955583748763743 0.8340143508170406 1.0 1.0 41 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Initiation of nuclear envelope ne reformation 0.40264587175114896 0.2091325412761524 0.8343447720628698 1.0 1.0 17 P50402,Q8IXJ6,Q86XL3,Q14739
Rhou gtpase cycle 0.40251498968013627 0.20877083385643863 0.8346271408268788 1.0 1.0 17 Q93008,O43396,P46940,Q8TAA9,O14964,Q01082,Q14155
Activation of the pre replicative complex 0.4128603180734725 0.20659377754057334 0.8363271202361973 1.0 1.0 20 Q07864,P33992,P33991,Q9Y619,P24941,P49642,P25205,P49736
Orc1 removal from chromatin 0.46239551229796033 0.20285111905986275 0.8392514012124557 1.0 1.0 51 P49721,O00231,P20618,O43242,Q9Y619,P28072,P51665,P60900,P28070,P28074
Platelet sensitization by ldl 0.36228964037122374 0.20154488073681354 0.8402725395895922 1.0 1.0 5 P30154,Q14738,Q16539
Rrna processing in the mitochondrion -0.3690133028345647 -0.20127253878120144 0.8404854740406111 1.0 1.0 5 Q7L0Y3,Q99714,O15091,Q9BQ52
Regulation of runx2 expression and activity 0.46083134613469556 0.20116466403923466 0.8405698206778593 1.0 1.0 44 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Myoclonic epilepsy of lafora 0.5641572691252541 0.20108268598313087 0.8406339200701811 1.0 1.0 1
Rhog gtpase cycle 0.4519928491564457 0.20094011533595513 0.8407453998805361 1.0 1.0 36 Q96JJ3,O15498,Q86Y07,Q13017,P50402,P61604,Q6IAA8,Q8TAA9,Q7L576,Q9NSV4,Q86XL3,P02786,O95202,O15173,Q14739
Cell extracellular matrix interactions 0.3596415599555639 0.1999355351901462 0.8415309984325963 1.0 1.0 8 Q9NVD7,Q15404
Mismatch repair 0.38248369597522514 0.19907353056739335 0.8422052263578503 1.0 1.0 13 P20585,Q9UQ84,P18858,P43246
Sumoylation -0.368473280443229 -0.1973089245895712 0.8435857958158821 1.0 1.0 81 Q9BW27,P38398,P46060,Q01831,Q14676,Q9NRG9,Q99497,Q92769,P78406,Q15424,P37198,P11387,Q13263,P55735,P49790,Q9UKX7,P45973,P04637,Q99496,Q96MF7,Q9Y2X3,P52948,Q92841,Q9HC52,Q9NQS7,P17844,Q9BVL2,Q15022,Q14683,Q96MG7,O75694,Q8NFH5,Q13547,Q9UER7,P06748,P61956,Q13363,Q12888,P12004
The role of gtse1 in g2 m progression after g2 checkpoint 0.4607921695908263 0.1968504111144111 0.8439446004774196 1.0 1.0 49 P49721,O00231,Q9NYZ3,P20618,P28072,Q15691,P51665,P60900,P28070,P28074
Metabolism of nucleotides -0.43695330672829935 -0.1967482965390912 0.8440245135238895 1.0 1.0 47 Q9UKK9,Q96DE0,Q9H0P0,P33316,P00491,P00492,P23919,P54819,P22392,O15067,P20839,P00390,P36639,P22102,P22234,P00568,P04183,P15531,P23921,P27144,Q9BW91,P12268
Rhobtb3 atpase cycle -0.39761043962442866 -0.19629207666497708 0.8443815626643032 1.0 1.0 4 Q15345
Slc mediated transmembrane transport 0.41254962129532813 0.19627251132953064 0.8443968757031644 1.0 1.0 21 Q70HW3,P12236,P35613,Q9Y6M7,Q9UBX3,P30825,Q92581,P53985,P11166,Q8TB61
Assembly of the orc complex at the origin of replication -0.34581140723611703 -0.19488184131802905 0.8454854501655158 1.0 1.0 8 P84243
Crmps in sema3a signaling 0.3470595266559345 0.19305250951264943 0.8469178448483963 1.0 1.0 6 O14786,Q14195
Sensory processing of sound by outer hair cells of the cochlea -0.3661234718715543 -0.19253895840821508 0.847320054343693 1.0 1.0 13 Q14651,P23634,Q6IBS0
Signaling by activin 0.5601950624809381 0.19204256037755182 0.8477088674787034 1.0 1.0 1
Signaling by nodal 0.5601950624809381 0.19204256037755182 0.8477088674787034 1.0 1.0 1
Estrogen stimulated signaling through prkcz 0.5601950624809381 0.19204256037755182 0.8477088674787034 1.0 1.0 1
Constitutive signaling by overexpressed erbb2 0.3680302994342417 0.19089338624266888 0.8486091219072289 1.0 1.0 4 Q16543,P07900
Pre notch processing in golgi -0.39537292266705226 -0.19050432527104538 0.8489139541754915 1.0 1.0 4 Q15363
Signaling by scf kit -0.34377487140750274 -0.1900021996895138 0.8493074068277968 1.0 1.0 8 P42224,P07947,Q13322,Q06124
Transport of mature transcript to cytoplasm -0.4225702125640315 -0.18917409595882326 0.849956369508357 1.0 1.0 61 Q9BW27,Q9UBU9,Q9NRG9,Q10570,P78406,O00148,P37198,Q16629,P55735,P84103,Q9UKX7,Q9Y5S9,Q8IYB3,Q09161,P38919,P52948,Q9P2I0,Q9BVL2,Q07955,Q05519,P26368,Q13838,O75694,Q8NFH5,P06730,Q13769,Q96J01
Negative regulation of nmda receptor mediated neuronal transmission 0.34555122530478066 0.18901826074658798 0.8500785047637209 1.0 1.0 6 Q14168,Q14012
Protein folding -0.4266558509125879 -0.18754147622404332 0.8512361072100143 1.0 1.0 37 P40227,P36404,P04637,P62873,O75347,P62879,P48643,Q9BVA1
Formation of rna pol ii elongation complex -0.4108237649197362 -0.18246448645502827 0.8552182221868554 1.0 1.0 29 Q96ST2,Q09161,P55199,Q15370,P19387
Fc epsilon receptor fceri signaling 0.4551099874908288 0.18154548886230165 0.8559394313585145 1.0 1.0 52 P25787,P49721,O00231,Q15008,P20618,O43242,P63208,P28072,P28070,O43865,P51665,P60900,P07948,P61088,P28074
Cd28 co stimulation 0.3566252677258962 0.1790970815708129 0.8578614735281411 1.0 1.0 9 P42345
Fructose catabolism -0.5723864675403941 -0.17844493605742529 0.8583735616946733 1.0 1.0 1 Q3LXA3
Assembly and cell surface presentation of nmda receptors -0.34759236939518784 -0.1784254775785284 0.8583888421104502 1.0 1.0 10 Q15334,Q9BVA1
Collagen biosynthesis and modifying enzymes 0.3559562877456201 0.1773779489717288 0.8592115268413869 1.0 1.0 9 Q32P28
Egr2 and sox10 mediated initiation of schwann cell myelination 0.3592653463771359 0.17360088885704456 0.8621791334218087 1.0 1.0 4 P46939,Q16850
Smooth muscle contraction -0.3494143925455017 -0.1730595607798237 0.8626046110949288 1.0 1.0 11 P60660,P08133
Formation of apoptosome -0.4400731930466497 -0.17199131758070602 0.8634443548533213 1.0 1.0 3 Q96GX9,P28482,Q9NR28
Meiotic recombination -0.35301808988460376 -0.1719504634208645 0.8634764732927398 1.0 1.0 12 P84243
Role of abl in robo slit signaling -0.4396074581630103 -0.1709968584340129 0.8642262358215809 1.0 1.0 3 Q01518
Tp53 regulates metabolic genes -0.41466846552878694 -0.17074734752403184 0.8644224315251485 1.0 1.0 34 O14548,P04637,P10606,P61981,O94925,P32119,P14854,Q9Y2Q5,Q9Y3B8,P30044
Growth hormone receptor signaling -0.3565008252639179 -0.17040800537064224 0.8646892768469028 1.0 1.0 5 P18031
Regulation of expression of slits and robos 0.22324931894071495 0.17008752755871034 0.8649413021613519 1.0 1.0 123 P49721,P62857,P62081,P61353,P61513,P62841,O43242,P28072,P42766,P28070,P20618,P51665,P62277,P28074,O00231,P46777,P62269,P62750,P60900,P62847
Acyl chain remodelling of ps 0.5498323681804191 0.16978164622705313 0.8651818615466431 1.0 1.0 1
Signaling by pdgfr in disease -0.35611840097651337 -0.16950639684416763 0.8653983412146564 1.0 1.0 5 P42224,P62993,O43815,Q6UN15,P40763
Signaling by notch4 0.4493820207453761 0.1684516641197516 0.8662279666514681 1.0 1.0 44 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Mitotic g2 g2 m phases 0.3642646606091647 0.16821856302455016 0.8664113378552618 1.0 1.0 86 P25787,P49721,Q9H6D7,P41208,O43242,P28072,O94927,P28070,Q13561,Q15008,O75935,P20618,P24941,Q96CW5,P51665,P06493,P28074,Q9NYZ3,O00231,P63208,Q15691,P60900,Q14203
Metabolism of rna -0.2476006777042398 -0.1672872987405033 0.8671439974525947 1.0 1.0 464 Q9NPD3,Q9UBU9,Q9Y2Z2,Q15029,O00567,O43143,P16383,O95453,P62304,Q9Y3B4,P47914,Q6P2E9,Q7L0Y3,Q8TEQ6,Q9Y3C4,Q9Y221,P63220,Q96F86,P14866,P08865,Q9UK45,Q9UKX7,Q9Y5S9,P62312,P32969,P38919,Q15061,Q9BVL2,Q92499,P62888,Q07955,Q13838,Q15269,Q8IWZ8,Q8NFH5,P18077,Q9C0C2,Q9H0D6,O94906,P05388,Q96GA3,P61289,Q8NI36,Q15366,Q99714,P25398,O75832,Q9UMS4,Q9BWJ5,Q15365,P25786,P37198,P41223,P46776,Q15007,Q9Y333,P62318,P62316,Q9BQA1,Q16629,Q9Y3I0,Q2VPK5,Q8IYB3,P55769,Q09161,P05387,P52948,Q00839,Q8IWX8,Q86U42,Q9NQT4,Q9Y5J1,Q13601,P09234,P63173,P27635,Q9BV38,Q10570,P15170,P55265,P61247,P62263,O14818,Q15393,Q9NX24,P25789,P26368,Q13769,Q96J01,Q9Y3C6,P62249,P05386,P19387,Q9Y4Z0,Q96DI7,P83881,P30050,Q96I25,Q9H8H0,Q12788,P78406,O00148,Q9UIV1,P84103,Q9UET6,P17844,O00232,Q05519,P62851,O75694,O94992,O43447,P62333,Q9GZL7
P75ntr regulates axonogenesis -0.43724282540418125 -0.1659911845995893 0.8681638876038158 1.0 1.0 3 P61586
Sema3a pak dependent axon repulsion 0.34161574499881286 0.165861109158946 0.8682662538978236 1.0 1.0 7 O14786,P08238,P07900
Fcgamma receptor fcgr dependent phagocytosis 0.41921203103211413 0.16555801517402785 0.8685047902581238 1.0 1.0 27 O43865,Q7L576,Q8IV08,O15143,P07948,P35579,Q9UQB8
Aspartate and asparagine metabolism -0.3523258542061028 -0.16070089287379077 0.872328986163613 1.0 1.0 5 P00505
Inhibition of replication initiation of damaged dna by rb1 e2f1 -0.32159654769220736 -0.16052902089307713 0.8724643626879653 1.0 1.0 6 P09884
Tcr signaling 0.4478631432371598 0.16032096165078066 0.8726282474343083 1.0 1.0 47 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members -0.565071624504735 -0.1603052338600223 0.8726406361714178 1.0 1.0 1 P40763
Pou5f1 oct4 sox2 nanog activate genes related to proliferation -0.565071624504735 -0.1603052338600223 0.8726406361714178 1.0 1.0 1 P40763
Transcriptional regulation of pluripotent stem cells -0.565071624504735 -0.1603052338600223 0.8726406361714178 1.0 1.0 1 P40763
Interleukin 10 signaling -0.565071624504735 -0.1603052338600223 0.8726406361714178 1.0 1.0 1 P40763
Deactivation of the beta catenin transactivating complex -0.3383827180937534 -0.1583795120445195 0.8741577570311241 1.0 1.0 10 Q15291,P35222,Q13547,Q13363,P63104
Tnfr2 non canonical nf kb pathway 0.4448077626805216 0.15813339733149082 0.8743516844253678 1.0 1.0 43 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Factors involved in megakaryocyte development and platelet production -0.41709591735404306 -0.1575364355348055 0.8748220949742356 1.0 1.0 42 Q14807,P13861,Q9H0B6,P04637,O95235,Q8IWA4,Q00535,Q92769,P27144,Q9BVA1,Q9NRW7,O60333,P84243
Nectin necl trans heterodimerization -0.5638524839987918 -0.15738073232260422 0.8749447976001863 1.0 1.0 1 Q9BY67
Arms mediated activation 0.5431270953977304 0.15643872557082358 0.8756872143343282 1.0 1.0 1
Activation of smo 0.5422127400182728 0.15468340598539282 0.8770709126311258 1.0 1.0 1
Platelet adhesion to exposed collagen 0.5770155043601276 0.1537252387020316 0.8778263837124978 1.0 1.0 2
Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.5416031697653012 0.15352171256090527 0.8779868691190926 1.0 1.0 1
Runx3 regulates notch signaling 0.5416031697653012 0.15352171256090527 0.8779868691190926 1.0 1.0 1
E3 ubiquitin ligases ubiquitinate target proteins 0.3801064112223918 0.15132724563249608 0.8797175778579669 1.0 1.0 17 Q14527,O75150,P78527,Q9BUN8,Q6PD62,P50542,Q92541,P61088
Gdp fucose biosynthesis -0.429846313560164 -0.15080499865201077 0.8801295430120477 1.0 1.0 3 A2VDF0,O60547
Ntrk2 activates rac1 0.5400792441328719 0.15064724389739886 0.8802539914037719 1.0 1.0 1
Activated ntrk2 signals through fyn 0.5400792441328719 0.15064724389739886 0.8802539914037719 1.0 1.0 1
Killing mechanisms 0.5400792441328719 0.15064724389739886 0.8802539914037719 1.0 1.0 1
Rhob gtpase cycle 0.40725020935553946 0.15030301940865665 0.8805255509091421 1.0 1.0 25 O14578,Q13017,Q13464,Q8TAA9,P02786,P41440
Mrna decay by 3 to 5 exoribonuclease 0.3713187874222619 0.14952645542057522 0.8811382356125295 1.0 1.0 15 Q6PGP7,Q969T7
Hdr through single strand annealing ssa 0.37129098313459274 0.14946127472163723 0.8811896643872807 1.0 1.0 15
Homologous dna pairing and strand exchange 0.37129098313459274 0.14946127472163723 0.8811896643872807 1.0 1.0 15
Tp53 regulates transcription of caspase activators and caspases -0.5979655325650551 -0.1493390002363452 0.8812861425648115 1.0 1.0 2 P04637
Cytochrome p450 arranged by substrate type 0.4067413470866813 0.1482895252314985 0.882114281621224 1.0 1.0 3
Runx1 regulates transcription of genes involved in differentiation of hscs 0.4400679200965851 0.14813980858766887 0.8822324333126168 1.0 1.0 42 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Dna damage reversal -0.346655921530512 -0.1479999513616075 0.8823428066273529 1.0 1.0 5 Q9H1I8,Q9C0B1
Zbp1 dai mediated induction of type i ifns 0.34410368579045736 0.14654194971534298 0.8834935762515617 1.0 1.0 4 Q9Y6K9
Rip mediated nfkb activation via zbp1 0.34410368579045736 0.14654194971534298 0.8834935762515617 1.0 1.0 4 Q9Y6K9
Synthesis of dolichyl phosphate -0.5961824775001312 -0.14630243800361137 0.883682641319762 1.0 1.0 2 P53602
Transmission across chemical synapses -0.4126950126414405 -0.1462916916959227 0.8836911243646854 1.0 1.0 45 P05091,P62873,P62879,P80404,P08754,O94925,P04899,P51649,Q15334,Q9BVA1
Rna polymerase ii transcription -0.3012469033874692 -0.14499878387460627 0.884711831970773 1.0 1.0 319 O14548,O75376,O95696,P61289,Q99873,P32119,Q9Y2Q5,O14497,Q9Y3B8,O75832,Q71SY5,Q10570,Q92769,P84243,O96017,Q5TA45,P04179,O00148,P10809,O94925,O60244,Q9H9B1,Q13526,P62318,P55199,Q16629,Q9UIV1,P84103,Q9Y5S9,O14818,P04637,Q8IYB3,P10606,Q9NWH9,Q09161,P18031,Q68CP9,Q99496,Q9NVM9,Q9ULW0,Q03164,Q15370,P30044,P61964,Q92922,P25789,Q96ST2,P26368,Q86U42,Q9UER7,Q00535,Q13769,P61981,P14854,Q96J01,O96019,P07947,P12004,P19387
Disinhibition of snare formation -0.5951219512194953 -0.14451177416356673 0.8850963596045309 1.0 1.0 2 Q12846,O00186
Grb2 sos provides linkage to mapk signaling for integrins 0.5701219512195119 0.14393117247709517 0.8855548198916745 1.0 1.0 2 P62993
Positive epigenetic regulation of rrna expression -0.3884721795328015 -0.14216426030897236 0.8869502611516851 1.0 1.0 28 Q9NY93,Q9GZS1,Q8WXI9,Q3B726,Q13547,Q92769,P35659,Q9H9Y6,Q9BQG0,P84243,O15446
Sumo is conjugated to e1 uba2 sae1 -0.4241329026499533 -0.13956803502077986 0.8890012977318074 1.0 1.0 3 P61956
Processing and activation of sumo -0.4241329026499533 -0.13956803502077986 0.8890012977318074 1.0 1.0 3 P61956
Sumo is transferred from e1 to e2 ube2i ubc9 -0.4241329026499533 -0.13956803502077986 0.8890012977318074 1.0 1.0 3 P61956
Synthesis of pi -0.5920451993318285 -0.13938194947014462 0.88914833535981 1.0 1.0 2 O96017
Transcriptional regulation by runx2 0.43992048562415487 0.13863598449662226 0.8897378063600163 1.0 1.0 52 P49721,O00231,P11802,P20618,P28072,P51665,P60900,P28070,P28074
Mitochondrial protein import 0.42980823735110385 0.13853703490246239 0.8898160021732724 1.0 1.0 37 Q8N4H5,Q9NS69,O60830,Q99595,P21796
M phase 0.27525352648022056 0.13795929843134486 0.8902725850301845 1.0 1.0 190 P25787,P49721,Q8NBT2,Q6IBW4,Q9H6D7,Q14738,Q96EA4,P41208,Q9Y6G9,Q92621,Q92674,O43683,Q86Y07,P68400,P50402,O43242,P28072,Q06323,Q13257,O94927,P28070,Q14739,Q13561,Q9BTX1,Q8N1F7,Q29RF7,Q15008,Q15021,O75935,P20618,Q96CW5,P51665,P06493,P28074,O00231,P50748,Q9H0U4,P57740,Q15691,Q8NFH4,P60900,Q8IXJ6,O60763,Q86XL3,Q14203,Q14204
N glycan antennae elongation in the medial trans golgi 0.5653837115301784 0.13747426606990484 0.8906559323026617 1.0 1.0 2
Reactions specific to the complex n glycan synthesis pathway 0.5653837115301784 0.13747426606990484 0.8906559323026617 1.0 1.0 2
The canonical retinoid cycle in rods twilight vision -0.5550137153307038 -0.13702440257559284 0.8910115065710711 1.0 1.0 1 Q8TC12
Downstream signaling events of b cell receptor bcr 0.4365382662847342 0.13701720873166592 0.8910171927981385 1.0 1.0 43 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Rna polymerase i transcription initiation -0.36059664725942925 -0.13633093098367952 0.8915596727630222 1.0 1.0 19 Q9GZS1,Q8WXI9,Q3B726,Q13547,Q9H9Y6,Q92769,O15446
Rhobtb1 gtpase cycle -0.3636100985784876 -0.13605201347412338 0.8917801623918642 1.0 1.0 20 Q16643,Q8IYB3
C type lectin receptors clrs 0.4386306276614048 0.13476592727523626 0.8927969461195666 1.0 1.0 51 P25787,P49721,O00231,Q15008,P20618,O43242,P63208,P28072,P28070,O43865,P51665,P60900,P07948,P61088,P28074
Dna damage telomere stress induced senescence -0.34178166333561455 -0.13383057265389198 0.8935365511737305 1.0 1.0 14 P10412,P16403,P04637,Q9Y294
Clec7a dectin 1 signaling 0.43760118174715734 0.13347938412767227 0.8938142674508658 1.0 1.0 47 P25787,P49721,O00231,Q15008,P20618,O43242,P63208,P28072,P28070,O43865,P51665,P60900,P61088,P28074
Infectious disease -0.20467146516393642 -0.13198426349461626 0.894996738764402 1.0 1.0 339 P63173,P27635,Q02750,O75376,P46060,P61289,P83881,Q99873,P30050,O75531,P25398,O75832,Q92769,P25786,P78406,P62873,P13639,P08754,P37198,P04899,P46776,P63220,P55199,Q9BVA1,P62942,P61247,P18754,P62263,P27797,O00422,P08865,O14818,Q14974,P12235,Q9NWH9,P62879,Q09161,P05387,P20839,P27824,P52948,P19387,P17844,Q12849,Q15370,Q9BVL2,P25789,P62851,Q86U42,P55072,Q13409,Q9UER7,P18077,Q15185,P63167,P14314,P78362,P62249,P07947,P05386,P09496,P12268
Traf3 dependent irf activation pathway -0.5874999999999845 -0.13198135474154418 0.8949990394873717 1.0 1.0 2 Q14258,Q7Z434
Rrna processing -0.22596465451851735 -0.13168621517278098 0.8952324892557548 1.0 1.0 168 P63173,P27635,P05388,Q96GA3,Q9NPD3,P83881,P30050,Q9BV38,Q8NI36,Q99714,O00567,P25398,Q9H8H0,Q12788,P47914,P46776,Q7L0Y3,Q9Y221,P63220,P61247,P08865,P62263,P55769,P05387,P32969,Q15061,Q9NX24,P62888,P62851,Q15269,Q9NQT4,P18077,Q9H0D6,Q9Y5J1,Q13601,P62249,Q9GZL7,P05386
Irf3 mediated activation of type 1 ifn 0.5291069795793812 0.1311947922037527 0.8956212155707095 1.0 1.0 1
Signal regulatory protein family interactions -0.4196964860661353 -0.13114182548257347 0.8956631149033212 1.0 1.0 3 Q06124
Rac1 gtpase cycle 0.4340298793522052 0.13089756941075137 0.8958563374688986 1.0 1.0 43 O15498,Q14155,Q86Y07,Q13017,P50402,O14578,Q6IAA8,P46940,Q8TAA9,Q68EM7,Q7L576,Q14739,Q9NSV4,P02786,Q9UQB8
Signaling by mapk mutants 0.5603658536585363 0.13087914053039876 0.8958709161721894 1.0 1.0 2 Q99956
Activation of the ap 1 family of transcription factors 0.5603658536585363 0.13087914053039876 0.8958709161721894 1.0 1.0 2 Q16539
Phase i functionalization of compounds 0.36265703573418384 0.12991419176646607 0.8966343160417967 1.0 1.0 15 O43169,P07099
Esr mediated signaling -0.40153753567219125 -0.12933462644668056 0.8970928735743628 1.0 1.0 42 P62879,P62873,P08754,P04899,Q15185,P17844,P84243,P19387
Transcriptional activity of smad2 smad3 smad4 heterotrimer -0.31445379668906087 -0.12831968449676093 0.8978959879062933 1.0 1.0 8 Q13547,O75376,Q9UPN9
Degradation of the extracellular matrix -0.3225439554232918 -0.12759480364714304 0.8984696436080661 1.0 1.0 10 O15484,Q92542,O15446
Interferon alpha beta signaling -0.3181375615744729 -0.1272093817143261 0.8987746801741578 1.0 1.0 9 P18031,P55265,Q06124
Nf kb is activated and signals survival 0.5266686985674944 0.12716498279527952 0.8988098200124508 1.0 1.0 1
P75ntr recruits signalling complexes 0.5266686985674944 0.12716498279527952 0.8988098200124508 1.0 1.0 1
P75ntr signals via nf kb 0.5266686985674944 0.12716498279527952 0.8988098200124508 1.0 1.0 1
Selective autophagy 0.41283947769899854 0.12646158448433376 0.8993665560021502 1.0 1.0 31 Q14204,Q8N4H5,Q9NS69,P68400,P07900,P19784,P08670,P54619,Q96E29,Q9Y6G9,P21796,P61088,Q15388
Regulation of tlr by endogenous ligand 0.5260591283145227 0.12617395367197592 0.8995942285290164 1.0 1.0 1
Irak4 deficiency tlr2 4 0.5260591283145227 0.12617395367197592 0.8995942285290164 1.0 1.0 1
Signaling by erbb2 -0.32954446222531386 -0.12569151533427472 0.899976118382783 1.0 1.0 12 P40818,P61586,Q96RT1,Q9UNE7,P07947
Interleukin 1 signaling 0.43472386864330514 0.1255374996155191 0.9000980394458382 1.0 1.0 48 P25787,P49721,O00231,Q15008,P20618,O43242,P63208,P28072,P28070,Q9H0E2,P51665,P60900,P61088,P28074
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4343855720818294 0.12503979906040819 0.9004920424821274 1.0 1.0 53 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Plasma lipoprotein assembly remodeling and clearance -0.3567366554910466 -0.12415833803396353 0.9011899083651509 1.0 1.0 20 P38571,P01130,P07237
Recycling pathway of l1 0.37557547217577253 0.12405795260004754 0.9012693898696902 1.0 1.0 19 P51812,Q15418,P26038,P35241,P15311
Akt phosphorylates targets in the cytosol 0.3294691885296015 0.12384070434531512 0.9014414024573261 1.0 1.0 4 P49840,P49841,P31751
Assembly of the hiv virion 0.5542682926829265 0.12319868626799908 0.9019497658511342 1.0 1.0 2 Q99816
Peroxisomal protein import 0.3857188885470725 0.12313972868266665 0.9019964517241121 1.0 1.0 22 O14975,Q9BY49,Q15067,Q9UKG9,O15254,O75874
Pi metabolism -0.34601773870858266 -0.12251089703803672 0.9024944164125035 1.0 1.0 17 Q13496,Q13614
Rhoc gtpase cycle 0.41320349203577594 0.12224026064790379 0.9027087421379429 1.0 1.0 32 Q13017,Q13464,P46940,P28288,Q8TAA9,P02786,P41440,Q14739
Mitotic g1 phase and g1 s transition 0.3853344732226678 0.12159507590433619 0.9032197134108753 1.0 1.0 78 P25787,P49721,P00374,P30154,P07948,P11802,O43242,P28072,Q06323,P25205,P28070,Q07864,Q15008,P20618,P24941,P51665,P49642,P49736,P06493,P28074,O00231,P33992,P33991,P63208,Q9Y619,P60900
Switching of origins to a post replicative state 0.4263241231913641 0.1213594156320977 0.9034063608580054 1.0 1.0 61 P49721,O00231,P20618,O43242,Q9Y619,P28072,P51665,P60900,P28070,P28074
Signaling by ptk6 0.33636105238032277 0.12058371278650715 0.9040207700108212 1.0 1.0 10 Q96JJ3,Q8IZL8,P11802,P23246,P24941
Ion homeostasis -0.32598704582136934 -0.11956642263511405 0.904826619712314 1.0 1.0 12 P05023,P23634,P30626
Cardiac conduction -0.32598704582136934 -0.11956642263511405 0.904826619712314 1.0 1.0 12 P05023,P23634,P30626
Ire1alpha activates chaperones 0.393390078411079 0.1190823955674011 0.9052100777941439 1.0 1.0 25 P43307,Q13217,O95070,O43731,O76024,Q14203,O14773
Biosynthesis of epa derived spms 0.5214873514172349 0.11894886902568542 0.9053158646799107 1.0 1.0 1
Dna replication initiation -0.332465417731361 -0.11867646012256779 0.905531686827431 1.0 1.0 5 P09884
Protein localization 0.3842362681593561 0.11791705265966285 0.9061333814454107 1.0 1.0 78 Q7L5D6,P09601,Q9NS69,Q15067,O60830,Q15388,Q99595,P21796,Q8N4H5,P06576,P50402,P28288,Q13505,P51659,P46379,P51648,Q9Y584,Q9UKG9,O14975,Q9BY49,O15254,O75874
Transcriptional activation of mitochondrial biogenesis -0.33251354192491356 -0.11776558426714971 0.9062533995173756 1.0 1.0 14 Q00059,O75376,P04179
Pka mediated phosphorylation of key metabolic factors 0.5199634257848057 0.11662128729722468 0.9071601680080419 1.0 1.0 1
Hdl assembly 0.5199634257848057 0.11662128729722468 0.9071601680080419 1.0 1.0 1
Budding and maturation of hiv virion -0.3314006713457524 -0.11661920323504826 0.9071618195798825 1.0 1.0 5 Q99816,Q9UN37,Q8WUM4,Q9NZ09,Q9NP79
Regulation of lipid metabolism by pparalpha -0.36607699769183905 -0.1165615498860952 0.9072075087058338 1.0 1.0 25 O75376,P50416,Q13503,O60244,Q96EK7,Q71SY5,P11310
Neurotransmitter receptors and postsynaptic signal transmission -0.3867731110801918 -0.11559677229190364 0.9079721210958556 1.0 1.0 36 P62879,P62873,P08754,P04899,Q15334,Q9BVA1
Digestion -0.5446510210301867 -0.11505060476949519 0.9084050115073823 1.0 1.0 1 O00625
Digestion and absorption -0.5446510210301867 -0.11505060476949519 0.9084050115073823 1.0 1.0 1 O00625
Snrnp assembly -0.3893828141548283 -0.11424396383751731 0.9090444019238344 1.0 1.0 39 Q9UKX7,Q9BW27,P62304,P78406,O75694,Q8NFH5,Q09161,P37198,Q9BVL2,Q9NRG9,Q8TEQ6,P62318,P52948,P62316,Q9BQA1
Activation of atr in response to replication stress 0.37435998933978787 0.11388389455912076 0.9093298327772235 1.0 1.0 20 P33992,P33991,Q9Y619,P24941,P25205,P49736
Signaling by type 1 insulin like growth factor 1 receptor igf1r -0.3298748855660758 -0.1137060133255546 0.9094708454974558 1.0 1.0 5 P31751,P62993,Q06124,O14654,Q99570
Hedgehog off state 0.42943657985094874 0.11196760880811911 0.9108490894609542 1.0 1.0 50 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Activation of nima kinases nek9 nek6 nek7 0.32047925171821695 0.1115296446666439 0.9111963591916648 1.0 1.0 4
Uptake and actions of bacterial toxins -0.3043364208426772 -0.11077915992179325 0.9117914715931845 1.0 1.0 8 Q02750,P13639,Q8WUM4
Epha mediated growth cone collapse 0.33121394653494896 0.10999582697510578 0.9124126844250415 1.0 1.0 10 P35580,P07948,Q13464
Apoptotic cleavage of cellular proteins 0.36490734461249974 0.10970704313622254 0.9126417145215999 1.0 1.0 18 Q16625,Q13464,P35611,P08670,P51572
Developmental biology -0.21662976828463112 -0.10890905867913109 0.9132746216001786 1.0 1.0 256 Q02750,P63173,O75376,P27635,P61289,P83881,P30050,P25398,O75832,Q71SY5,P84243,P15170,Q92769,Q92542,P25786,Q01518,O60244,P24468,P46776,P63220,Q96S59,Q9BVA1,P61247,P08865,P62263,Q9Y5S9,O14818,Q9NWH9,P60660,Q09161,P05387,P23528,Q96EK7,Q03164,Q15334,Q15370,P61964,P25789,P62851,Q13503,Q00535,P18077,P61586,P09497,P62249,P07947,P05386,P09496,P19387
Notch4 intracellular domain regulates transcription 0.5417682926829266 0.1085826854472759 0.9135334945551745 1.0 1.0 2 Q04721
Regulation of beta cell development 0.5417682926829265 0.10858268544727562 0.9135334945551747 1.0 1.0 2 P31751
Pcp ce pathway 0.42758034902644865 0.10755614391385061 0.9143477871883468 1.0 1.0 51 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Anchoring of the basal body to the plasma membrane 0.3905709897370143 0.10708283857713571 0.9147232617088012 1.0 1.0 26 O75935,Q9H6D7,Q15691,O94927,P41208,P06493,Q14203,Q14204,Q15019,Q13561
Nef and signal transduction 0.5402439024390241 0.10690258929222447 0.9148662590067405 1.0 1.0 2 Q13177
Negative epigenetic regulation of rrna expression -0.359620905665857 -0.10689496821345583 0.914872305103519 1.0 1.0 25 O00422,Q3B726,Q15393,Q92769,P84243,O15446
Neutrophil degranulation 0.2561045648557991 0.1068806794049844 0.914883640981635 1.0 1.0 171 P25787,P06744,P42785,Q13217,P51148,P15586,P01889,P11216,Q9Y6G9,P04066,P30519,P07858,O43242,P18206,P46940,P11717,Q93050,Q9H7Z7,P16278,Q7Z6Z7,Q13510,Q8WVQ1,Q9BTY2,Q15008,P20618,Q6IAA8,Q9H0E2,P51665,O15126,Q7L576,P06280,O00584,P10253,P13473,Q9NZJ7,O00231,O14975,Q13464,Q9NZ32,Q86VP6,P10619,P42025,Q9Y376,Q14204,Q07065,O00264,O75874
Diseases of signal transduction by growth factor receptors and second messengers -0.19892820033776368 -0.10578239310646176 0.9157550066663411 1.0 1.0 144 Q02750,P25789,O75376,O14818,P55072,P61289,Q9NWH9,Q09161,Q32MZ4,Q6WCQ1,Q86WB0,P62942,P35232,Q13363,O75832,Q92542,Q92769,P19387
Tp53 regulates transcription of cell death genes -0.2917865551987594 -0.10456618949088498 0.916720044461133 1.0 1.0 6 Q92597,P04637
Transcription of the hiv genome -0.36395469713386913 -0.10308438797124131 0.9178959956024348 1.0 1.0 28 P55199,Q15370,Q09161,P19387
Free fatty acids regulate insulin secretion -0.5679878048780368 -0.10261708270788147 0.9182668843754478 1.0 1.0 2 O60488,O95573
Negative regulation of fgfr1 signaling -0.35600976205002544 -0.10142872132263556 0.9192101377183439 1.0 1.0 4 P62993,P28482,P30153,Q06124
Spry regulation of fgf signaling -0.35600976205002544 -0.10142872132263556 0.9192101377183439 1.0 1.0 4 P28482,P30153,Q06124,P62993
Negative regulation of fgfr2 signaling -0.35600976205002544 -0.10142872132263556 0.9192101377183439 1.0 1.0 4 P62993,P28482,P30153,Q06124
Negative regulation of fgfr3 signaling -0.35600976205002544 -0.10142872132263556 0.9192101377183439 1.0 1.0 4 P62993,P28482,P30153,Q06124
Negative regulation of fgfr4 signaling -0.35600976205002544 -0.10142872132263556 0.9192101377183439 1.0 1.0 4 P62993,P28482,P30153,Q06124
Signaling by the b cell receptor bcr 0.42326055519167954 0.10106127866319045 0.9195018157738959 1.0 1.0 46 P49721,O00231,P20618,O43242,P28072,O43865,P51665,P60900,P28070,P28074
Ripk1 mediated regulated necrosis 0.3356880157146126 0.1009520769395185 0.9195885028076949 1.0 1.0 12 P07900,Q13546,Q16543,O00560,P41440,O75955
Regulation of bach1 activity -0.3556378537561333 -0.10070572421443769 0.9197840672125968 1.0 1.0 4 Q13309,O14867
Sensory processing of sound -0.3344838702849565 -0.09968207700696516 0.920596730137905 1.0 1.0 18 Q14651,P23634,Q6IBS0
Hsf1 activation -0.3171206937708254 -0.09965981143828175 0.9206144074670406 1.0 1.0 13 P55072,Q15185
Signaling by moderate kinase activity braf mutants -0.31697104887574834 -0.0994428085734958 0.9207866948595267 1.0 1.0 13 P35232,P41240,Q02750
Nr1h2 and nr1h3 mediated signaling -0.29275853968486093 -0.09927352165179172 0.9209211012077265 1.0 1.0 7 O75376
Metabolism of steroids 0.42364457762589014 0.09910780504501794 0.9210526750712491 1.0 1.0 49 O14975,Q15392,Q15436,O95772,Q9HCL2,Q15800,Q53GQ0,Q9BWD1,P04062,Q15648,Q9UBM7,Q14534,Q16850,Q14739,P51659
Fatty acid metabolism 0.419870912998159 0.09889434925133463 0.9212221555574813 1.0 1.0 59 Q16836,Q15067,Q9UMR5,Q14914,Q9H7Z7,P50897,O43772,Q4G176,Q53GQ0,Q8N8N7,Q9UKG9,O15254
Interleukin 21 signaling -0.5652439024390129 -0.09879964333646729 0.9212973516854528 1.0 1.0 2 P42224,P40763
Interleukin 9 signaling -0.5652439024390129 -0.09879964333646729 0.9212973516854528 1.0 1.0 2 P42224,P40763
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.5312060115007269 0.09738959391493149 0.9224170082984042 1.0 1.0 2
Condensation of prophase chromosomes -0.30762124208410685 -0.09695437460886883 0.9227626274663472 1.0 1.0 11 P84243
Signaling by fgfr1 -0.32041501373208087 -0.09656012263018243 0.9230757259868654 1.0 1.0 5 P28482,P30153,P62993,Q06124,P19174
Signaling by fgfr3 -0.32041501373208087 -0.09656012263018243 0.9230757259868654 1.0 1.0 5 P28482,P30153,P62993,Q06124,P19174
Signaling by fgfr4 -0.32041501373208087 -0.09656012263018243 0.9230757259868654 1.0 1.0 5 P28482,P30153,P62993,Q06124,P19174
Nervous system development -0.19277799076044905 -0.09582923179001065 0.923656200582043 1.0 1.0 209 Q02750,P63173,P27635,P05388,P61289,P83881,P30050,P25398,O75832,Q92542,Q92769,P15170,P25786,Q01518,P46776,P63220,Q96S59,Q9BVA1,P61247,P08865,P62263,Q9Y5S9,O14818,Q9NWH9,P60660,Q09161,P05387,P32969,P23528,P38919,P61158,Q06124,Q15334,Q15370,P62888,P25789,P62851,Q00535,P18077,P61586,P09497,P62249,P07947,P05386,P09496
Plasma lipoprotein clearance -0.3248665117318816 -0.0955177854692871 0.9239035640861888 1.0 1.0 16 P38571,P01130
Chl1 interactions 0.36906636731122355 0.09551190462460524 0.9239082349662764 1.0 1.0 3
Rhof gtpase cycle 0.3573225260064269 0.09501222797439669 0.9243051143424033 1.0 1.0 18 Q8TAA9,Q9UEY8,P12814,Q13017
Interleukin 1 family signaling 0.42195928459824195 0.09497916886729492 0.9243313729446387 1.0 1.0 50 P25787,P49721,O00231,Q15008,P20618,O43242,P63208,P28072,P28070,Q9H0E2,P51665,P60900,P61088,P28074
Pecam1 interactions -0.35263039196591606 -0.09494221882372808 0.9243607221862682 1.0 1.0 4 P07947,Q06124
Cristae formation -0.33370164254044116 -0.09430641283007388 0.9248657559194735 1.0 1.0 19 Q5XKP0,O75947,Q9BUR5,P25705,P38646
Pkmts methylate histone lysines -0.32014857591540774 -0.09378122005112507 0.9252829501564463 1.0 1.0 15 Q15291,Q9H9B1,Q03164,Q96L73,P61964
Degradation of beta catenin by the destruction complex 0.42119887206459666 0.09376772455622738 0.9252936707630477 1.0 1.0 49 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Class i peroxisomal membrane protein import 0.31272493346934394 0.09265041648027982 0.9261812894090027 1.0 1.0 8 O43808,P51648,P28288
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.3653214852859793 0.09124872394643323 0.9272949602952705 1.0 1.0 3 P18887
Signaling by wnt in cancer -0.2870044450851596 -0.09083637471382437 0.9276226066728603 1.0 1.0 7 Q13363
Integrin cell surface interactions 0.30201342281879934 0.08999184034321916 0.9282936989821455 1.0 1.0 4 Q9Y624,P35613,Q08722
P75 ntr receptor mediated signalling -0.32404318162698653 -0.08998495983691203 0.9282991666486777 1.0 1.0 17 Q92542,Q92769,P61586
Interconversion of nucleotide di and triphosphates -0.3288751146928404 -0.08808770059499284 0.9298069718810922 1.0 1.0 19 P33316,P23919,P54819,P00568,P22392
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.30210558437594215 0.08655676825952659 0.9310238308018823 1.0 1.0 5 P10321,P78310,P04439,P01889
Telomere extension by telomerase -0.2997098439990924 -0.08610574131221695 0.9313823596708901 1.0 1.0 11 O60832,Q9NX24,Q9NY12,O15084,Q9BUR4,Q9Y265
Fgfr1 mutant receptor activation -0.2950894588431215 -0.08514677856329218 0.9321447013946875 1.0 1.0 10 P42224,Q16630,Q32MZ4,O15164,O94905,Q92614
Abc family proteins mediated transport 0.4172574772355517 0.08497566857573319 0.9322807343931561 1.0 1.0 53 P49721,O00231,P20618,P08183,P28072,P51665,P60900,Q9BUN8,P28070,P28074
Metabolism of vitamins and cofactors -0.3702497099656601 -0.08478075859050309 0.9324356908769826 1.0 1.0 50 Q96CD2,P05165,Q96RQ3,P11498,P01130,Q13085
Hdr through mmej alt nhej 0.30788026878435537 0.08395623414085225 0.9330912289560243 1.0 1.0 8 P49916,P49959,P09874,P39748,O60934,P18887,Q92878
Runx3 regulates p14 arf 0.516463414634146 0.08347464708098697 0.9334741357205336 1.0 1.0 2 P42771
Rhod gtpase cycle 0.38030540296110543 0.08210571398502554 0.934562649365505 1.0 1.0 27 Q13017,P50402,Q8TAA9,Q9UEY8,Q68EM7,Q9NSV4,O15173,Q14739,P12814
Semaphorin interactions -0.33213828599040723 -0.08165895459783215 0.9349179187910301 1.0 1.0 22 Q9NWH9,P60660,Q00535,P61586,P23528
Myogenesis 0.29670329670329904 0.08162246706647901 0.9349469347689185 1.0 1.0 6 P19022,O60271,P60953,Q16539,P35221
Oas antiviral response -0.38982325034375925 -0.08126829596889358 0.9352285867192442 1.0 1.0 3 P21333
Neurotransmitter clearance -0.5513577774623533 -0.080646763831223 0.9357228751377777 1.0 1.0 2 P05091
Sumoylation of intracellular receptors -0.551330136371362 -0.08061255599846458 0.9357500804626675 1.0 1.0 2 P61956
Cyclin a b1 b2 associated events during g2 m transition 0.3146359121820531 0.07930837383071755 0.936787345929915 1.0 1.0 10 P30154,P30153,P24941,P06493,Q99640
Chaperone mediated autophagy -0.27696828084655356 -0.07753733257402329 0.9381960935538891 1.0 1.0 7 Q99497
Negative regulation of mapk pathway -0.2885262256705217 -0.07696893651967351 0.9386482567034655 1.0 1.0 10 Q02750
Adherens junctions interactions -0.2762826101454316 -0.07669302465484024 0.9388677537174746 1.0 1.0 7 O60716,P35222,P14923
Formation of the cornified envelope 0.29376241267324177 0.07662352965978317 0.9389230400174526 1.0 1.0 6 P07384,Q02487
Keratinization 0.29376241267324177 0.07662352965978317 0.9389230400174526 1.0 1.0 6 P07384,Q02487
Rhobtb2 gtpase cycle -0.32194073501890375 -0.07655994645536021 0.9389736234880095 1.0 1.0 20 Q13838,P40227,Q8IYB3,P78371,Q16643,Q8WWQ0
Chromatin modifying enzymes -0.32742174590750117 -0.07649822328751132 0.9390227274463308 1.0 1.0 73 O75376,O95696,Q99873,Q8IUF8,O14497,Q96L73,Q92769,Q9H9B1,Q96ES7,Q9BQA1,O00422,Q15291,Q15393,Q68CP9,Q12824,Q03164,P61964,P51610,Q92922,Q6IA86,O96019
Selenoamino acid metabolism -0.260987892158156 -0.07615335676461431 0.9392970907849563 1.0 1.0 91 P63173,P27635,P05388,P41252,P83881,P30050,P25398,P23526,P56192,P47914,P46776,P63220,P61247,P08865,P62263,Q15046,P00390,P05387,P32969,P14868,P57772,P62888,P62851,P18077,P62249,P05386
Activation of nmda receptors and postsynaptic events 0.36111027062639706 0.07606819880236014 0.9393648404918262 1.0 1.0 22 Q14168,P54619,P52292,Q14012,P51812,Q15418,Q14155
Neuronal system -0.35830665855202104 -0.07463679361856623 0.940503698679735 1.0 1.0 53 P05091,P62873,P62879,P80404,P08754,P04899,O94925,P51649,Q15334,Q9BVA1
Ncam1 interactions -0.5220969216702378 -0.07417380119640075 0.9408720920291029 1.0 1.0 1 P13591
Cellular response to chemical stress 0.3727037542012903 0.07326623570728212 0.9415942594670463 1.0 1.0 77 P49721,P09601,O00231,O75182,P13073,P20618,O43242,P28072,P51665,P60900,P28070,P30519,P28074
Basigin interactions 0.29662143215834474 0.07316149960376643 0.9416776031151151 1.0 1.0 7 P53985,P35613,P05026
Metalloprotease dubs 0.2916347691587501 0.07287658831325375 0.9419043242142826 1.0 1.0 5 O95630
Rho gtpase effectors -0.15634644370460485 -0.07269979088116582 0.9420450149631925 1.0 1.0 109 O43663,Q9BVA1,Q9H0B6,P21333,P46060,Q13409,P49454,P60660,P61981,P61586,P53350,P23528,P63167,Q13526,P52948,Q15334,Q9Y3B8,P84243
Tnf signaling -0.2806012000082273 -0.0722758827622061 0.9423823572584671 1.0 1.0 9 Q6GQQ9,Q12933,P63244
Nonsense mediated decay nmd -0.2765727593767885 -0.07174609851399373 0.9428039693551584 1.0 1.0 86 P63173,P27635,P05388,P83881,P30050,P25398,P15170,P46776,P63220,P61247,P08865,P62263,Q9Y5S9,Q09161,P05387,P32969,P38919,P62888,P62851,P18077,P62249,P05386
Recruitment of mitotic centrosome proteins and complexes 0.3770117709402664 0.07156634585015108 0.9429470234944604 1.0 1.0 28 O75935,Q9H6D7,Q15691,Q96CW5,O94927,P41208,P06493,Q14203,Q13561
Vldlr internalisation and degradation -0.27175572519084634 -0.07132020214602591 0.9431429171822094 1.0 1.0 7 O94973,Q96CW1,O95782,P63010,P53680,Q00610,P09496
Rho gtpases activate paks -0.28563744919133516 -0.06943253276960615 0.9446453339905032 1.0 1.0 11 Q7Z406,P21333,P60660,Q14247,P62140
Amino acids regulate mtorc1 -0.28921952888863217 -0.06935976497460217 0.9447032546546945 1.0 1.0 12 P55735,P21283,P21281,Q9Y2Q5,P38606
Ctla4 inhibitory signaling 0.29405936666162047 0.0690486594079164 0.9449508872876378 1.0 1.0 7 Q14738,P07948
Golgi associated vesicle biogenesis 0.3664395082631912 0.06870411894253013 0.9452251395116904 1.0 1.0 25 Q14789,P50570,P11717,O00443,P51148,O95295,P51809,O60749,P02786,O75976,O00203,Q00610,Q99523
Raf activation -0.2846688245724721 -0.06840377058915081 0.945464220366864 1.0 1.0 11 P35232,Q02750
Eukaryotic translation initiation -0.1858124084750367 -0.06732725000190665 0.94632118373759 1.0 1.0 102 P63173,P27635,Q13347,P05388,O75822,P83881,P30050,P25398,O15371,P47914,P46776,P56537,P63220,P61247,P08865,P62263,O00303,P05387,P32969,P62888,P62851,P18077,P62249,P05386
Ksrp khsrp binds and destabilizes mrna -0.2934751625678101 -0.06656576051196762 0.9469274044165452 1.0 1.0 14 O95453,Q9Y3B2,Q9NPD3,Q9NQT4,Q92945,Q13868,Q15024,Q06265,P63104
Hdr through homologous recombination hrr 0.3618706431068438 0.0664543142129403 0.9470161292397681 1.0 1.0 24 Q9UQ84
Smad2 smad3 smad4 heterotrimer regulates transcription 0.33939346857370506 0.06627485447334562 0.9471590024232235 1.0 1.0 3
Other interleukin signaling -0.3790789874961811 -0.06623955870960123 0.9471871026202543 1.0 1.0 3 Q12846,P40222,P42574
Regulation of tp53 expression and degradation -0.2821078439885974 -0.06575502940065601 0.9475728600451034 1.0 1.0 11 O96017,Q9UER7,P04637
Uptake and function of diphtheria toxin 0.27332659426024697 0.0656946807131051 0.9476209074424744 1.0 1.0 4 P07900
Peptide hormone metabolism -0.29179636902019307 -0.06492139255582613 0.9482365877267083 1.0 1.0 14 P62873,O00471
Rho gtpases activate iqgaps -0.26991315172731956 -0.06491979949319365 0.9482378561310072 1.0 1.0 8 Q9BVA1
Muscle contraction -0.32470583891877086 -0.06463883677865505 0.9484615620742605 1.0 1.0 26 P11532,P06753,P60660,P08133,P30626,P05023,P23634
Apc c cdc20 mediated degradation of cyclin b 0.31895435689286544 0.06458812388842655 0.948501940729906 1.0 1.0 13 Q9UJX4,Q13042,Q9UJX2,Q9UJX6,Q12834,Q9UJX5,P06493
Apc c mediated degradation of cell cycle proteins 0.40236438168082905 0.0642831963462761 0.9487447331519518 1.0 1.0 61 P49721,O00231,P20618,O43242,P28072,P51665,P60900,P28070,P28074
Polb dependent long patch base excision repair 0.29062878900765604 0.06373439283393292 0.949181718885578 1.0 1.0 7
Processing of smdt1 0.30946549101799325 0.06366324172381217 0.9492383742005583 1.0 1.0 11 Q9BPX6,Q99623,Q9H300,Q9UJZ1,Q96TA2,Q9Y4W6
Sars cov 2 infection -0.3132616498605609 -0.06292375826930431 0.9498272159666163 1.0 1.0 22 P55072,Q99873,P14314,P78362,P27824,P17844
Platelet activation signaling and aggregation -0.33809995157912304 -0.06258532707332327 0.9500967138095815 1.0 1.0 57 P41240,P37802,Q9Y6I9,P55145,O00186,Q01518,P63096,P62873,P08754,P04899,Q9UHQ9,P07602,P21333,P62879,O75083,P18031,P23528,Q06124,P04075,P61586
Metabolism of carbohydrates -0.18311449080001355 -0.06192352993549147 0.9506237292742841 1.0 1.0 97 P19367,P52209,P00505,P40926,P07686,P08236,P78406,P14618,P11498,P37198,P15121,P60174,Q7Z4W1,P40925,Q14376,P52948,Q9BVL2,P04075,P04406,P60891
Regulation of plk1 activity at g2 m transition 0.37588466091373085 0.06106228212898996 0.9513096075719019 1.0 1.0 30 O75935,P63208,Q9H6D7,Q15691,O94927,P41208,P06493,Q14203,Q13561
Mitotic telophase cytokinesis -0.27723374311829485 -0.0609942331663646 0.9513638017727732 1.0 1.0 11 Q14683,O95235,Q7Z5K2,P53350,Q6KC79
Ras activation upon ca2 influx through nmda receptor 0.28064586944040193 0.06040673976035234 0.9518316909095588 1.0 1.0 5
Long term potentiation 0.28064586944040193 0.06040673976035234 0.9518316909095588 1.0 1.0 5
Unblocking of nmda receptors glutamate binding and activation 0.28064586944040193 0.06040673976035234 0.9518316909095588 1.0 1.0 5
Mitochondrial biogenesis -0.3327340486226686 -0.060166291853355064 0.9520231922629903 1.0 1.0 34 O75376,P04179,Q00059,Q5XKP0,O75947,Q9BUR5,P25705,P38646
Rna polymerase iii transcription initiation from type 1 promoter -0.2714012530398764 -0.05894754995864968 0.9529938844812551 1.0 1.0 10 Q9Y5Q9,Q9UKN8
Trafficking of ampa receptors -0.2710880195599033 -0.058660418765141255 0.9532225862697339 1.0 1.0 10 O94973,Q96CW1,O95782,Q9UM54,P63010,P53680,Q13557,Q15334,Q13555,P46459
Trna processing -0.31842757024814905 -0.05827630108263823 0.9535285444225694 1.0 1.0 64 Q9BW27,Q9Y2Z2,P49792,Q9NRG9,Q9BQ52,Q99714,Q10570,P78406,O95059,P37198,O15091,Q7L0Y3,Q9Y3C4,Q9Y3I0,Q2VPK5,P49790,P55735,Q9UKX7,Q99567,Q5VV42,Q9UET6,P52948,Q9BVL2,Q92499,Q9NWX6,O75694,O94992,Q8NFH5,P35658,P07814,P78346
Vitamin b2 riboflavin metabolism -0.5114294422432349 -0.05804295086199785 0.9537144163346902 1.0 1.0 1 Q8NFF5
Cellular response to starvation -0.203030812971897 -0.05783414763189899 0.9538807378132752 1.0 1.0 89 P63173,P27635,P05388,P83881,P30050,Q9Y2Q5,P25398,P46776,P63220,P61247,P08865,P62263,P05387,P21283,P32969,P62888,P62851,P18077,P62249,P05386
Ngf stimulated transcription -0.37216107139730176 -0.05736031349088321 0.9542581761709921 1.0 1.0 3 Q00535
Regulation of pten localization -0.5105150868637776 -0.05675221618018069 0.9547425785112782 1.0 1.0 1 Q93009
Regulation of kit signaling 0.3263160957043131 0.05648579315587966 0.9549548128745178 1.0 1.0 3
Phosphorylation of emi1 0.2573439003887566 0.05634065349335718 0.955070433445405 1.0 1.0 4
Uch proteinases 0.4013383442858013 0.0561894898586884 0.9551908538137213 1.0 1.0 48 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Non integrin membrane ecm interactions 0.2764918636208014 0.05617554117248646 0.9552019657040367 1.0 1.0 5 Q9Y296
Irs mediated signalling -0.32977425259303994 -0.05596482549561882 0.955369828412632 1.0 1.0 4 P62993,P31751,Q06124,Q99570
Signal attenuation -0.37025945824494283 -0.055027339508590296 0.9561166830073184 1.0 1.0 3 Q13322
Rhoq gtpase cycle 0.3574344366287925 0.05485573902013783 0.9562533938958446 1.0 1.0 25 Q13017,Q6IAA8,P46940,Q8TAA9,Q15642,Q68EM7,Q9NSV4,Q9HD26,P02786,Q14155
Antigen processing cross presentation 0.40182336066028973 0.05481016593177179 0.9562897013364573 1.0 1.0 53 P49721,O00231,Q9UIQ6,P20618,P28072,P51665,P60900,P28070,P28074
Response of eif2ak1 hri to heme deficiency -0.2921966978721496 -0.05462924425141799 0.956433839996802 1.0 1.0 5 P41091,Q13322,P05198
Signaling by csf3 g csf 0.28880044680910466 0.054008254305807274 0.9569285878568892 1.0 1.0 8 Q93034
Transport of the slbp dependant mature mrna -0.31873210058307183 -0.053655821255317614 0.9572093815957992 1.0 1.0 31 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,Q9UBU9,Q09161,P06730,P37198,Q9NRG9,P52948,Q9BVL2,P55735
Activation of gene expression by srebf srebp 0.335769333414507 0.053549802258509874 0.9572938510778017 1.0 1.0 19 Q14534,Q15648,Q9HCL2,Q16850
Erythropoietin activates ras -0.3686649073943607 -0.05310655843506855 0.9576470059534521 1.0 1.0 3 P46109
Interleukin 7 signaling 0.4727427796487143 0.05284559720310444 0.9578549309189603 1.0 1.0 2
Eukaryotic translation elongation -0.24065109817944466 -0.0524732872663588 0.9581515796763385 1.0 1.0 77 P63173,P27635,P05388,P83881,P30050,P25398,P47914,P13639,P46776,Q05639,P63220,P61247,P08865,P62263,P05387,P32969,P62888,P62851,P18077,P62249,P05386
Transport of mature mrnas derived from intronless transcripts -0.3213888363573423 -0.05181636265343155 0.9586750175537802 1.0 1.0 36 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,Q9UBU9,Q09161,P06730,P37198,Q9NRG9,P52948,Q9P2I0,Q9BVL2,Q10570,P55735
Response of eif2ak4 gcn2 to amino acid deficiency -0.2070834205731944 -0.051626144690251126 0.9588265866635606 1.0 1.0 77 P63173,P27635,P05388,P83881,P30050,P25398,P47914,P46776,P63220,P61247,P08865,P62263,P05387,P32969,P62888,P62851,P18077,P62249,P05386
Butyrate response factor 1 brf1 binds and destabilizes mrna -0.26926507776300673 -0.05126435922143975 0.9591148679646995 1.0 1.0 12 Q9Y3B2,Q9NPD3,Q9NQT4,Q8IZH2,Q13868,Q06265,Q15024
Dna double strand break response -0.2960220701978677 -0.050146691332309916 0.9600054922151473 1.0 1.0 22 Q99496,O96017,Q92560,P04637
Hiv life cycle -0.2288021397692526 -0.049901626816535295 0.960200780908445 1.0 1.0 73 P78406,P46060,Q09161,P37198,O75531,P52948,P19387,P55199,Q15370,Q9BVL2,P18754
Neurexins and neuroligins 0.28991978192693457 0.049044708610444306 0.9608836664690963 1.0 1.0 9 Q14168
Respiratory electron transport -0.3119242296110697 -0.048759982790421146 0.9611105733249157 1.0 1.0 52 O14548,P21912,P38117,Q86Y39,O95299,P10606,P19404,Q9BU61,P14854,O75251,P49821,O95182,P13804,P31040
Rna polymerase iii transcription -0.26198968431695624 -0.04834697484804489 0.961439717785338 1.0 1.0 11 Q9Y5Q9,Q9UKN8
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins -0.2891326686946889 -0.04795673990570942 0.9617507194654111 1.0 1.0 61 P38117,Q86Y39,O95299,P10606,O75947,P19404,P25705,P14854,O75251,P49821,O95182,P13804,P31040
Dna replication pre initiation 0.391752413693633 0.047838058059752664 0.9618453053180616 1.0 1.0 63 P49721,O00231,P20618,O43242,Q9Y619,P28072,P51665,P60900,P28070,P28074
Meiotic synapsis 0.30710347388091447 0.04774164264929668 0.9619221458884095 1.0 1.0 13
Processive synthesis on the lagging strand -0.27017063021086035 -0.047333013759747085 0.962247816385551 1.0 1.0 14 P49005,P09884,P12004
Metabolism of water soluble vitamins and cofactors -0.31118949566098664 -0.046255861769419856 0.9631063188323405 1.0 1.0 42 Q96CD2,P05165,Q96RQ3,P11498,Q13085
Pi 3k cascade fgfr2 -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Frs mediated fgfr4 signaling -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Activated ntrk2 signals through frs2 and frs3 -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Pi 3k cascade fgfr3 -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Frs mediated fgfr3 signaling -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Signaling by flt3 itd and tkd mutants -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Frs mediated fgfr2 signaling -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Frs mediated fgfr1 signaling -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Tie2 signaling -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Stat5 activation -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Pi 3k cascade fgfr4 -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Pi 3k cascade fgfr1 -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Stat5 activation downstream of flt3 itd mutants -0.5189930479461534 -0.04566360722236089 0.9635783707642587 1.0 1.0 2 Q06124
Interferon signaling -0.1599388704729546 -0.04563347962971312 0.9636023840729069 1.0 1.0 65 Q9BW27,Q9NRG9,P78406,P55265,P37198,Q13526,Q9UKX7,P21333,Q14974,O00629,P18031,P38919,P52948,Q06124,Q9BVL2,O75694,Q8NFH5,P06730,P60842
Ret signaling -0.23981872006515298 -0.04518693314737053 0.9639583094501274 1.0 1.0 6 Q13322,Q06124
Glucose metabolism -0.25997715308647773 -0.04439485474804545 0.9645896629233535 1.0 1.0 60 P04075,Q9UKX7,P00505,P19367,P40926,P78406,P40925,O75694,Q8NFH5,P14618,P11498,P37198,P06733,P60174,P52948,P04406,Q9BVL2
Sars cov infections -0.2469970732076174 -0.04382315337006994 0.9650453710904607 1.0 1.0 60 O00422,P55072,P20839,Q15185,Q99873,P14314,P78362,P27824,P17844,P62942,Q92769,P12268
Lipophagy 0.3034461726136008 0.04331592544124848 0.9654496964707633 1.0 1.0 3 P11142,P54619
Rrna modification in the nucleus and cytosol -0.25464832674591226 -0.04314216616477061 0.9655882068334567 1.0 1.0 58 Q8NI36,Q9NY12,O00567,O00425,Q9UNX4,Q9H8H0,Q12788,Q9Y3A4,Q9Y6V7,P62263,P55769,Q15061,Q9Y2X3,Q9BVJ6,Q9NX24,Q15269,O60832,Q9Y5J1,Q13601
Signaling by receptor tyrosine kinases 0.19430189662492742 0.043084383704347404 0.9656342677386518 1.0 1.0 111 Q93034,Q8WX92,Q14738,P11233,P07948,P16949,O14786,Q9UQB8,Q93050,Q15904,P51812,Q96J02,Q9Y487,O43865,Q16543,Q7L576,Q15418,Q96JJ3,Q13464,P42345,O14964,Q9Y6I3
Interleukin 12 family signaling -0.29555857713718103 -0.042699655402981644 0.9659409542692439 1.0 1.0 30 P05388,P04179,P14174,P23528,P27824,P07237,O00170,P38646
Mitotic prophase -0.15173146675535076 -0.04269220482540971 0.9659468935541025 1.0 1.0 59 Q9UKX7,P02545,P78406,Q8NFH5,P37198,P53350,O75531,P52948,Q9BVL2,P84243
Ecm proteoglycans 0.3019213174748402 0.042598823804565936 0.966021333108722 1.0 1.0 3 P13591,P05067
Signaling by fgfr1 in disease -0.25109426771252946 -0.0412105372794453 0.9671280532760334 1.0 1.0 11 P42224,Q16630,Q32MZ4,O15164,O94905,Q92614
Rhov gtpase cycle 0.31845056991808474 0.04089775224903597 0.9673774093953247 1.0 1.0 17 Q93008,O43396,P46940,Q8TAA9,Q16512,Q01082,Q00610,Q14155
Interleukin 12 signaling -0.2866691950723396 -0.04067419633868745 0.9675556329056108 1.0 1.0 27 P05388,P04179,P14174,P23528,P07237,O00170,P38646
Apc cdc20 mediated degradation of nek2a 0.3057335635883869 0.040519650867039174 0.9676788407793366 1.0 1.0 14 O43684,Q9UJX4,Q13042,Q13257,Q9UJX6,Q12834,Q9UJX5
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3057335635883869 0.040519650867039174 0.9676788407793366 1.0 1.0 14 O43684,Q9UJX4,Q13042,Q13257,Q9UJX6,Q12834,Q9UJX5
Linoleic acid la metabolism 0.44493075808624605 0.04037297937532164 0.9677957720146948 1.0 1.0 2
Regulation of tp53 activity -0.20381183477786027 -0.04029905598519612 0.9678547063838967 1.0 1.0 54 O96017,O95696,P04637,Q9UER7,Q00535,Q9H9B1,Q13526,Q9ULW0,Q92769
Ion channel transport 0.3557324106345028 0.04011098129618182 0.9680046470400314 1.0 1.0 28 Q9C0H2,Q9Y487,Q15904,Q93050,P98194
Signaling by gpcr -0.26837895064982864 -0.03943774576381705 0.9685413865380612 1.0 1.0 48 P07602,P62136,P62879,P62873,P08754,P04899,Q00535,P61586
Cargo recognition for clathrin mediated endocytosis -0.28874820778227034 -0.03937993716426159 0.9685874753239716 1.0 1.0 35 Q96D71,P09497,P01130,P20645
Mhc class ii antigen presentation -0.20056525127563904 -0.03931236690307533 0.968641346876183 1.0 1.0 52 Q14807,Q9H0B6,O94855,O95235,P53634,Q13409,Q9BTE1,P63167,P27824,P53992,Q9BVA1,P09496
Sumoylation of dna damage response and repair proteins -0.2595307661935388 -0.039210242478025265 0.9687227676009971 1.0 1.0 49 Q9BW27,P38398,Q01831,Q14676,Q9NRG9,P78406,P37198,P55735,Q9UKX7,Q99496,Q96MF7,Q9HC52,P52948,Q9BVL2,Q14683,Q96MG7,O75694,Q8NFH5,P61956
Signaling by egfr 0.29584067546217646 0.03912808007913728 0.9687882734409616 1.0 1.0 12 O14964,Q9Y6I3
Hcmv infection -0.25501114481121484 -0.038953057425342115 0.9689278149313083 1.0 1.0 49 Q15022,Q9UKX7,Q9BW27,O75376,P78406,O75694,Q8NFH5,Q13409,Q9UER7,P37198,P63167,Q9NRG9,Q9BRG1,P52948,Q13263,Q9BVA1,Q9BVL2,P55735
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s -0.2179131614224718 -0.03893028720564741 0.9689459691677977 1.0 1.0 51 P62263,P62851,Q13347,O75822,P63220,P25398,P62249,P61247,P08865
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants -0.355901189387003 -0.038877051764370354 0.9689884127732162 1.0 1.0 3 P42224,P40763,P62993
Interleukin 2 family signaling -0.355901189387003 -0.038877051764370354 0.9689884127732162 1.0 1.0 3 P42224,P40763,P62993
Epigenetic regulation of gene expression -0.2768908508679853 -0.03883767496000127 0.9690198072073806 1.0 1.0 44 O00422,Q3B726,Q15393,Q92769,Q96T88,P84243,O15446
Death receptor signalling -0.28156416986650745 -0.03880090525810101 0.9690491230879101 1.0 1.0 27 P61586,Q12933,P63244,Q92542,Q92769
Antiviral mechanism by ifn stimulated genes -0.17244065408020193 -0.03877799825831374 0.9690673864844546 1.0 1.0 51 P42224,Q9BW27,P49792,Q9NRG9,P19525,P78406,P37198,Q14258,Q13526,O75369,P55735,P49790,Q9UKX7,P21333,Q14974,O00629,Q99567,P38919,P52948,Q9BVL2,O75694,Q8NFH5,P35658,P06730,P60842
Diseases of metabolism -0.26357781846172423 -0.03863147540807846 0.9691842072695016 1.0 1.0 47 P05165,Q96RQ3,P11498,P22570,Q13085,Q7Z4W1,P23526
Chromosome maintenance -0.20361149929122527 -0.037865277235059204 0.9697950979361956 1.0 1.0 49 P46100,O15084,Q9UER7,P12004,P09884,Q9NX24,P49005,Q96T23,P84243,P19387
Perk regulates gene expression -0.2584627057395597 -0.037714827170601276 0.9699150540351622 1.0 1.0 16 P41091,O95453,Q9Y3B2,Q9NPD3,Q9NQT4,Q92945,P05198,Q13868,Q06265,Q15024
Aurka activation by tpx2 0.3506980990174662 0.03745306678352433 0.9701237611490414 1.0 1.0 27 O75935,Q9H6D7,Q15691,O94927,P41208,P06493,Q14203,Q13561
Glycolysis -0.20737107219793832 -0.03740099052000018 0.970165282904027 1.0 1.0 48 P04075,Q9UKX7,P19367,Q9BW27,P78406,O75694,Q8NFH5,P14618,P06733,P37198,P60174,Q9NRG9,P52948,P04406,Q9BVL2
Sumoylation of chromatin organization proteins -0.27776670589846986 -0.03712935836102805 0.970381863574947 1.0 1.0 37 Q9BW27,P49792,Q9NRG9,Q92769,P78406,P37198,P55735,P49790,Q9UKX7,P45973,Q99567,Q99496,Q9HC52,P52948,Q9BVL2,Q15022,O75694,Q8NFH5,Q13547,P35658,P61956
Gene silencing by rna -0.24150244858332273 -0.037033089960023705 0.9704586218556497 1.0 1.0 46 P78406,Q99598,Q9BVL2,P84243,P19387
Interleukin 15 signaling 0.43506097560975565 0.0370092018308443 0.9704776687681165 1.0 1.0 2 P62993
Hcmv early events -0.25875824674578024 -0.03665137420464712 0.9707629803310256 1.0 1.0 43 Q15022,Q9UKX7,Q9BW27,O75376,P78406,O75694,Q8NFH5,Q13409,Q9UER7,P37198,P63167,Q9NRG9,P52948,Q13263,Q9BVA1,Q9BVL2,P55735
Endogenous sterols 0.43317408152283693 0.036422066724294926 0.970945819149448 1.0 1.0 2
Atf4 activates genes in response to endoplasmic reticulum stress -0.24729960272607468 -0.03616702901076792 0.9711491758185427 1.0 1.0 13 O95453,Q9Y3B2,Q9NPD3,Q9NQT4,Q92945,Q13868,Q06265,Q15024
Apoptosis 0.3090317669117052 0.036053183311195794 0.9712399523416397 1.0 1.0 90 P49721,Q16625,O00231,Q13464,P20618,P51572,P28072,P51665,P60900,P28070,P28074
Copi independent golgi to er retrograde traffic -0.2726853646556984 -0.036030448082995735 0.9712580806509319 1.0 1.0 27 P68402,Q13409,Q9BTE1,P63167,Q9BVA1
Deadenylation dependent mrna decay -0.26670369661316695 -0.03599345540575187 0.9712875774041738 1.0 1.0 39 O95453,Q9UK45,Q9NPD3,Q9Y4Z0,Q9NQT4,P62312,Q6P2E9,Q9C0C2,P38919,Q9Y333,Q96F86,Q9UIV1
Biological oxidations -0.23318967213446531 -0.03587507208901825 0.9713819726601758 1.0 1.0 44 O14880,P48506,P00387,P05091,Q9Y2Q3,P10768,P30837,O43488,P22570,Q15185,P31153,P78417,P21266,O00170,P23526,P11766,Q86WA6
Tristetraprolin ttp zfp36 binds and destabilizes mrna -0.24594677271336488 -0.03555741807845663 0.9716352622838083 1.0 1.0 13 Q9Y2L1,Q9Y3B2,Q92973,Q5RKV6,Q96B26,Q9NPD3,Q9NQT4,Q9NQT5,Q8IZH2,Q13868,P31946,Q06265,Q15024
Trna processing in the nucleus -0.2573650827594609 -0.03540653434778188 0.9717555743243709 1.0 1.0 40 Q9UKX7,Q9BW27,P78406,O75694,Q92499,O95059,O94992,Q9Y3I0,Q8NFH5,P37198,Q9NRG9,Q9BQ52,P52948,P78346,Q9BVL2,Q10570,P55735
Abc transporters in lipid homeostasis -0.3524558105502822 -0.03537738980934592 0.9717788137423184 1.0 1.0 3 P56589
Attenuation phase -0.23685819070904857 -0.03527535427613105 0.9718601755352174 1.0 1.0 10 P0DMV9,P11142,P07900,P54652,Q02790,P25685,Q15185,P50454,Q92598,P08238
Cytosolic sensors of pathogen associated dna 0.3136942450436299 0.03519545287788569 0.9719238880643437 1.0 1.0 17 P12956,Q9BUI4,Q13546,Q9UJV9,P78527,O15160,Q9Y6K9
Synthesis of substrates in n glycan biosythesis -0.2605816447970537 -0.03515826993542031 0.9719535374101624 1.0 1.0 20 Q9UJ70,O15305,O60547,A2VDF0,Q96EK6,P34949,P53602,Q9NR45,Q8NFW8
Telomere maintenance -0.2198230798702454 -0.035138575411045016 0.9719692416634884 1.0 1.0 43 P46100,Q9UER7,P12004,P09884,Q9NX24,Q9NY12,P49005,O15084,Q9Y265,P84243,P19387
Infection with mycobacterium tuberculosis 0.2964282787178857 0.034651186379914746 0.9723578851542434 1.0 1.0 13 O14964,Q63HN8,P23246,Q9H267
Response of mtb to phagocytosis 0.2964282787178857 0.034651186379914746 0.9723578851542434 1.0 1.0 13 O14964,Q63HN8,P23246,Q9H267
Fanconi anemia pathway 0.268396946564878 0.034478280631114536 0.9724957615949827 1.0 1.0 7 P15927,P35244,P27694,Q9BXW9,Q9NVI1,O15360
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand -0.26720624155622746 -0.03442808567899032 0.9725357876093812 1.0 1.0 30 Q13409,Q15185,Q9BTE1,P63167,Q9BVA1
Cellular senescence -0.21894800789363889 -0.03419077245145228 0.9727250247574637 1.0 1.0 41 Q99496,P10412,P04637,P84243
Establishment of sister chromatid cohesion 0.2680916030534276 0.0341366763167248 0.972768162046749 1.0 1.0 7 Q8N3U4,Q7Z5K2,Q9NTI5,O60216,Q9UQE7,Q29RF7
Sumoylation of dna replication proteins -0.25777619770851135 -0.034114159679531374 0.9727861172660592 1.0 1.0 36 Q9UKX7,Q9BW27,P78406,P46060,O75694,Q8NFH5,P37198,P11387,Q9NRG9,P52948,Q9NQS7,P61956,Q9BVL2,P12004,P55735
Gene and protein expression by jak stat signaling after interleukin 12 stimulation -0.2627226900534052 -0.03383635440822536 0.9730076459080683 1.0 1.0 25 P05388,P04179,P14174,P37837,P17987,P23528,P78417,O00170,P38646
Nuclear envelope breakdown -0.19284306555051475 -0.03345925351420131 0.9733083586096447 1.0 1.0 40 Q9UKX7,P02545,Q9BW27,P78406,O75694,Q8NFH5,P37198,P53350,Q9NRG9,O75531,P52948,Q9BVL2
Potential therapeutics for sars -0.2194862207263989 -0.03282320630425156 0.9738155722265753 1.0 1.0 38 O00422,P20839,Q15185,P62942,Q92769,P12268
Transcriptional regulation by small rnas -0.21985524613231966 -0.03238083339544467 0.974168347207129 1.0 1.0 37 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,P52948,Q9BVL2,P84243,P19387
Sumoylation of rna binding proteins -0.24484689943546376 -0.0323225396146648 0.9742148345808532 1.0 1.0 34 P49790,Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,Q99567,P35658,P49792,P37198,Q99496,Q9NRG9,Q9HC52,Q9Y2X3,P52948,P61956,Q9BVL2,P55735
Processing of dna double strand break ends 0.34640633089171696 0.03225116212342088 0.9742717559028078 1.0 1.0 27 Q9UQ84,P24941,Q9UNS1
Interactions of rev with host cellular proteins -0.24219903910732085 -0.032128272398961905 0.9743697569301693 1.0 1.0 34 P49790,Q9UKX7,Q9BW27,P55735,P78406,P46060,Q14974,Q99567,O75694,Q8NFH5,P49792,P37198,P35658,Q9NRG9,P06748,P52948,Q9BVL2,P18754
Interactions of vpr with host cellular proteins -0.24380619116373434 -0.03191186455894442 0.9745423369097246 1.0 1.0 33 Q9UKX7,Q9BW27,P78406,P12235,O75694,Q8NFH5,P37198,Q9NRG9,O75531,P52948,Q9BVL2
Extracellular matrix organization -0.25117161398381493 -0.0318579967394146 0.9745852953688623 1.0 1.0 30 P11532,P07237,P23284,O15484,Q92542,O15446
Cytosolic iron sulfur cluster assembly 0.2659541984732794 0.031789166824519266 0.9746401858933047 1.0 1.0 7 Q9Y5Y2,P18074,P28340,Q6FI81,Q96T76,O75027
Hiv elongation arrest and recovery -0.24792888058068002 -0.03174340075022975 0.9746766835179215 1.0 1.0 19 P55199,Q15370,P19387
Response to elevated platelet cytosolic ca2 -0.23218000406910902 -0.031152407081135997 0.9751479951208633 1.0 1.0 33 P55145,Q9UHQ9,O00186,P04075,Q01518,P07602,P21333,P37802,O75083,P23528,Q9Y6I9
Eph ephrin signaling -0.23543870611929069 -0.030975506256660283 0.9752890734727517 1.0 1.0 32 P09496,P60660,P61586,Q15375,P23528,P09497,P61158,P07947,Q92542
Ns1 mediated effects on host pathways -0.20624914434823888 -0.030753567169509395 0.975466070917764 1.0 1.0 34 Q9UKX7,Q9BW27,Q86U42,P78406,Q14974,O00629,O75694,Q8NFH5,P37198,Q9NRG9,P52948,Q9BVL2,P55735
G2 m dna damage checkpoint -0.19980231572510065 -0.03066160791016437 0.9755394092054532 1.0 1.0 34 O96017,P40938,P38398,P04637,P61981,Q12888,Q14676,Q04917,P27348,Q9Y3B8,Q9NWV8,P62258,P63104
Viral messenger rna synthesis -0.1861800469206446 -0.030541192789110452 0.9756354415962831 1.0 1.0 34 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,P52948,P19387,Q9BVL2,P55735
Hcmv late events -0.1758394613862361 -0.030493329260052538 0.9756736133882449 1.0 1.0 34 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,Q9BRG1,P52948,Q9BVL2,P55735
Nuclear import of rev protein -0.23285446231802887 -0.030461069310121942 0.9756993411527091 1.0 1.0 31 P49790,Q9UKX7,Q9BW27,P55735,P78406,Q14974,O75694,Q99567,Q8NFH5,P35658,P49792,P37198,Q9NRG9,P06748,P52948,Q9BVL2,P18754
Microrna mirna biogenesis -0.22736201038614468 -0.030251993814629414 0.9758660824169767 1.0 1.0 11 P19387
Prolactin receptor signaling 0.26517574559537727 0.030250922086922583 0.9758669371407773 1.0 1.0 3
Signaling by hedgehog 0.3863539892809069 0.030226083705470662 0.9758867462433867 1.0 1.0 56 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Rhobtb gtpase cycle -0.23401288276817095 -0.03020209371656357 0.9759058787502075 1.0 1.0 30 Q16643,Q8IYB3
Translation of sars cov 2 structural proteins -0.24031747791635266 -0.030117561855602652 0.9759732947486617 1.0 1.0 18 Q99873,P14314,Q16706,P27824,Q14697,P78362
Postmitotic nuclear pore complex npc reformation -0.24407706621574154 -0.030104123762714024 0.9759840119359648 1.0 1.0 23 Q9BW27,Q14974,P46060,O75694,Q8NFH5,P37198,P18754,P52948,Q9BVL2,P55735
Phase ii conjugation of compounds -0.2390863974579524 -0.030061325361180807 0.9760181446717215 1.0 1.0 28 O14880,P48506,P48507,Q9Y2Q3,P28161,P10768,O95861,O43252,P31153,P78417,P21266,P23526
Estrogen dependent gene expression -0.22909479449414402 -0.029536248061990303 0.9764369097709464 1.0 1.0 29 Q15185,Q99873,P17844,P84243,P19387
Signaling by ntrks -0.18123117757756718 -0.029078906153462293 0.9768016591341206 1.0 1.0 31 Q02750,P46109,Q00535,P61586,P09496
Rab regulation of trafficking -0.18042812738972014 -0.029073781201168464 0.9768057465262558 1.0 1.0 31 Q9NVG8,Q9UL25,Q9Y2L5
Cohesin loading onto chromatin 0.2681734880879623 0.028985255452264047 0.9768763500989768 1.0 1.0 8 Q8N3U4,Q7Z5K2,Q9NTI5,Q6KC79,O60216,Q9UQE7,Q29RF7
Translesion synthesis by y family dna polymerases bypasses lesions on dna template -0.2368683947403326 -0.028899420113837046 0.9769448081120202 1.0 1.0 22 Q8TAT6,P40938,P15927,P55072,P35250,Q92890,P35249,Q14258,Q15004,Q14694,P49005,P12004
Cargo trafficking to the periciliary membrane 0.3151827663084177 0.028109999995667205 0.9775744183829937 1.0 1.0 19 Q9UPT5,Q96KP1,Q8TAG9,A6NIH7
Export of viral ribonucleoproteins from nucleus -0.17417295197663724 -0.028082750232329846 0.9775961519684377 1.0 1.0 29 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,P52948,Q9BVL2,P55735
Sumoylation of sumoylation proteins -0.19682620306718082 -0.027880290963106662 0.9777576278658633 1.0 1.0 28 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,P52948,P61956,Q9BVL2,P55735
Fcgr activation 0.39448296691344775 0.027694218574201974 0.9779060348460327 1.0 1.0 2
Neddylation 0.34087808669165304 0.02766018622442921 0.977933178334162 1.0 1.0 81 P25787,P49721,Q93034,Q9BTE7,Q96GG9,Q9UNS2,O43242,P28072,Q06323,P28070,Q15008,P20618,P51665,Q8NEZ5,O94952,P28074,Q7L5N1,O00231,Q99627,P63208,Q86VP6,P60900,Q15369,Q9Y5A7,Q13619,Q13618
Sumoylation of ubiquitinylation proteins -0.1787191949416195 -0.027639693432765417 0.9779495229671511 1.0 1.0 28 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,P52948,Q9BVL2,P55735
Pre notch processing in the endoplasmic reticulum 0.3932926829268289 0.027510359457792025 0.9780526773230795 1.0 1.0 2 Q04721
Regulation of glucokinase by glucokinase regulatory protein -0.18178268822466714 -0.027201124786540198 0.97829931858934 1.0 1.0 27 Q9UKX7,Q9BW27,P78406,O75694,Q8NFH5,P37198,Q9NRG9,P52948,Q9BVL2,P55735
Dna damage bypass -0.20570105912709724 -0.026882569417031262 0.9785533960838286 1.0 1.0 25 Q8TAT6,P55072,Q16531,Q15004,P49005,P12004
Regulation of mrna stability by proteins that bind au rich elements 0.379497769726261 0.026640865127165826 0.9787461791575534 1.0 1.0 63 P49721,O00231,P20618,O43242,P28072,P51665,P60900,P28070,P28074
Signaling by kit in disease 0.2339443782741534 0.026154680011534252 0.9791339636153238 1.0 1.0 5
Ephb mediated forward signaling -0.21796533147742664 -0.026055710262958987 0.9792129031471792 1.0 1.0 15 P61586,P23528,O15145,P61158,P07947
Phospholipid metabolism 0.38167230888174764 0.025610573202401933 0.9795679526411858 1.0 1.0 49 Q96PE3,P35790,P68400,Q8N2A8,Q9HCL2,Q9NPH0,Q8IV08,Q96N66,Q9NQZ5,Q8NCC3
Signaling by robo receptors 0.21310592938371226 0.025410063559331456 0.9797278841411301 1.0 1.0 136 P49721,O00231,P46777,P62269,P62841,P20618,O43242,P28072,P62857,P62081,P35080,P51665,P60900,P61353,P62277,P28070,P28074,P62847
Rhoh gtpase cycle 0.3237268375514363 0.025387866505442825 0.9797455891159963 1.0 1.0 22 Q13464,Q9BXS4,Q8TAA9,P02786,Q658Y4
G1 s specific transcription 0.27398066877706395 0.025250806740837597 0.9798549119386541 1.0 1.0 10 Q9Y619
Hiv transcription initiation 0.2919647275973573 0.025238676701833315 0.9798645872259906 1.0 1.0 14
Rab gefs exchange gtp for gdp on rabs -0.18354344036959241 -0.024983745336357353 0.980067928905032 1.0 1.0 22 Q9UL25,Q9Y2L5
Signaling by erythropoietin -0.30590953983231456 -0.02416180159638733 0.9807235471385771 1.0 1.0 4 P46109
Retrograde neurotrophin signalling -0.19883934025656821 -0.02398047563114287 0.9808681824181837 1.0 1.0 8 O94973,Q96CW1,O95782,P50570,P63010,P53680,Q00610,P09496
Ca dependent events 0.25796341001924283 0.02367557346980047 0.981111390090943 1.0 1.0 7 P52292,Q13557
Antigen presentation folding assembly and peptide loading of class i mhc 0.29870542666697214 0.02352050967504461 0.9812350786547246 1.0 1.0 16 Q9NZ08,O95486,Q15436,P51572
Transcriptional regulation by ventx -0.18723836559463286 -0.022838038712237597 0.981779465425215 1.0 1.0 16 Q9H9B1,P04637
Mecp2 regulates transcription of neuronal ligands -0.3382128697773671 -0.02238128843525657 0.9821438062793368 1.0 1.0 3 Q13547,P51608,Q96ST3
Processive synthesis on the c strand of the telomere -0.19092792740929096 -0.022244011626748935 0.9822533100634547 1.0 1.0 12 P49005,P12004
Cell death signalling via nrage nrif and nade -0.18872112594820692 -0.022014590917889366 0.9824363164894245 1.0 1.0 12 Q9NY61,P62258,Q92542,P42574
Transcriptional regulation by runx1 0.36152532226539136 0.020556911376445285 0.9835991129356079 1.0 1.0 72 P49721,Q16625,O00231,O75182,P20618,P28072,Q9HCL2,P51665,P60900,P28070,Q9HCE1,P28074
Cell cell junction organization 0.2636081821022387 0.019938839821382025 0.9840921615994838 1.0 1.0 9
Cargo concentration in the er 0.2895991290783685 0.01890101250681485 0.9849200718223345 1.0 1.0 15 O95486,Q96PC5,O95487,Q13190,Q15436,P49755,Q9Y6B6,Q12907
Signaling by notch 0.3759080930157622 0.01862603647000908 0.9851394323374907 1.0 1.0 61 P67809,P49721,O00231,P20618,P28072,P51665,P60900,P28070,Q9HCE1,P28074
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.2714766126566679 0.018588327808081184 0.9851695142886037 1.0 1.0 11 Q9UJX3,Q9UJX4,Q13042,Q16763,Q96DE5,P30260,Q9UJX2,Q9UJX6,Q12834,Q9UJX5
Rho gtpases activate rocks 0.26356294093305926 0.01581236696172597 0.9873840822619941 1.0 1.0 10 P35580,Q13464
Downregulation of erbb2 signaling 0.24805665417062447 0.015000205306381227 0.9880320165905117 1.0 1.0 7 Q93034,Q16543
Notch3 intracellular domain regulates transcription -0.32875876791704445 -0.015000083586408787 0.988032113698073 1.0 1.0 3 Q13573,P42224,Q15398
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2715596330275246 0.01476219628013895 0.9882218992914948 1.0 1.0 12 Q9UJX3,Q13309,Q9UJX4,Q13042,P06400,Q16763,Q96DE5,P30260,Q9UJX2,Q9UJX6,Q9UJX5
Signaling by braf and raf1 fusions 0.31555763530359937 0.014145213409306042 0.9887141289721715 1.0 1.0 23 P51114,Q6RW13,Q9NRY5
Downstream signaling of activated fgfr1 -0.3265762030602492 -0.013429822921737776 0.9892848737343494 1.0 1.0 3 Q06124
Downstream signaling of activated fgfr2 -0.3265762030602492 -0.013429822921737776 0.9892848737343494 1.0 1.0 3 Q06124
Downstream signaling of activated fgfr3 -0.3265762030602492 -0.013429822921737776 0.9892848737343494 1.0 1.0 3 Q06124
Downstream signaling of activated fgfr4 -0.3265762030602492 -0.013429822921737776 0.9892848737343494 1.0 1.0 3 Q06124
Glutathione synthesis and recycling 0.23931623931624132 0.012110203639441383 0.9903376916627324 1.0 1.0 6 P48507,Q8WUX2,P48637,Q96KP4,O75223
Rab geranylgeranylation 0.2966728306522203 0.010937762222786794 0.9912731023995982 1.0 1.0 19 P51148,Q9ULC3,Q9H0U4,P53611
Synthesis of diphthamide eef2 -0.2931726360243498 -0.01069251369924867 0.991468770965861 1.0 1.0 4 P13639
Gap filling dna repair synthesis and ligation in gg ner 0.29618877438800423 0.010554636217036192 0.9915787750723877 1.0 1.0 19 P35251,Q07864,P18858,P41440
Translesion synthesis by polh 0.26941788395405714 0.009580040121756233 0.9923563508139044 1.0 1.0 13
Deposition of new cenpa containing nucleosomes at the centromere 0.24013361352078766 0.0057893435028528025 0.9953807980051497 1.0 1.0 8
Dcc mediated attractive signaling -0.46006097560975645 -0.0052435754456458105 0.9958162512806097 1.0 1.0 2 P60953,P63000
Inositol phosphate metabolism 0.23736817144519198 0.004088295904461876 0.9967380209047141 1.0 1.0 8 Q96PE3,Q13572
Beta catenin independent wnt signaling 0.36427626514727685 0.002382159418922228 0.9980993135759033 1.0 1.0 57 P49721,O00231,P20618,P28072,P51665,P60900,P63218,P28070,Q9HCE1,P28074
Tp53 regulates transcription of genes involved in g1 cell cycle arrest -0.4522358220125886 -0.00176140182790662 0.998594605402858 1.0 1.0 2 P04637
Intra golgi traffic 0.260510320006631 0.0008250654954839551 0.9993416930541907 1.0 1.0 14 Q9UP83,O15498,Q13190,O00461,P83436,O95249
Rhoj gtpase cycle 0.24507989800014884 0.0 1.0 1.0 1.0 24 Q13017,Q6IAA8,Q8TAA9,P02786,Q14155
Vesicle mediated transport 0.2228357785465889 0.0 1.0 1.0 1.0 236 O60499,O15498,Q96KP1,Q8WTV0,P50570,Q15436,P51148,P15586,P11233,P61923,P02786,Q9Y6G9,O00203,O95249,Q9UNS2,Q99523,Q8TAG9,O15027,Q9UIQ6,Q96PC5,Q9Y296,O00461,P54619,P11717,P83436,O43731,O60749,Q4KMP7,Q8N6H7,Q14108,Q13561,Q8TD16,O95486,P24390,Q14789,O75935,Q5SW96,Q13190,Q9NVZ3,O95295,P51809,Q12893,O75976,P35579,P52594,Q9UP83,Q9P2W9,Q99627,Q9H0U4,Q9NZ32,Q9UPT5,Q15642,Q15907,O14964,O60763,Q96A65,Q9Y6I3,Q14203,Q14204
Clathrin mediated endocytosis 0.19015825420440907 0.0 1.0 1.0 1.0 56 Q92905,P50570,P51148,P02786,Q9UNS2,P59998,Q13492,P11717,O00443,Q14108,P61201,Q5SW96,Q13098,Q9NVZ3,P51809,O15144,P52594,Q7L5N1,Q99627,Q15642,O14964,Q9Y6I3,Q00610
Costimulation by the cd28 family 0.2303636803373809 0.0 1.0 1.0 1.0 14 P31751,P30154,P42345,P30153,Q14738,P62993,Q16512,P07948
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.23127781266648811 0.0 1.0 1.0 1.0 23 P41440
Recognition of dna damage by pcna containing replication complex 0.25191207998828913 0.0 1.0 1.0 1.0 19 Q07864,Q13619,P41440
Maturation of sars cov 2 spike protein 0.17949004178081643 0.0 1.0 1.0 1.0 12 P04843,P04844,Q9UKM7,P61803,P46977
Deadenylation of mrna 0.2110875818070652 0.0 1.0 1.0 1.0 15 A5YKK6,P23588,Q04637,Q9HBH5
Cell junction organization 0.24052724905577633 0.0 1.0 1.0 1.0 19 Q8N3R9,Q9NVD7,Q15404
Polymerase switching on the c strand of the telomere 0.2504806905954193 0.0 1.0 1.0 1.0 15 P49642,Q8WVB6,P41440
Membrane trafficking 0.21288444928670383 0.0 1.0 1.0 1.0 230 O60499,O15498,Q96KP1,P50570,Q15436,P51148,P15586,P11233,P61923,P02786,Q9Y6G9,O00203,O95249,Q9UNS2,Q99523,Q8TAG9,O15027,Q9UIQ6,Q96PC5,Q9Y296,O00461,P54619,P11717,P83436,O43731,O60749,Q4KMP7,Q8N6H7,Q14108,Q13561,Q8TD16,O95486,P24390,Q14789,O75935,Q5SW96,Q13190,Q9NVZ3,O95295,P51809,Q12893,O75976,P35579,P52594,Q9UP83,Q9P2W9,Q99627,Q9H0U4,Q9NZ32,Q9UPT5,Q15642,Q15907,O14964,O60763,Q96A65,Q9Y6I3,Q14203,Q14204
Termination of translesion dna synthesis 0.20384076797005657 0.0 1.0 1.0 1.0 19
Unfolded protein response upr 0.23434656354193367 0.0 1.0 1.0 1.0 43 P43307,Q13217,O95070,O43731,O76024,Q14203,O14773
Diseases of mitotic cell cycle 0.2065566795163411 0.0 1.0 1.0 1.0 17 P11802
Rho gtpases activate formins 0.19002912321995796 0.0 1.0 1.0 1.0 58 Q8NBT2,Q92674,P50748,O43683,P57740,P35080,Q14738,Q15691,Q8NFH4,Q9NSV4,Q96EA4,Q9Y6G9,Q14204
Organelle biogenesis and maintenance 0.24825591856816726 0.0 1.0 1.0 1.0 89 A6NIH7,Q96KP1,Q9H6D7,P41208,Q8TAG9,P06576,O75964,Q13505,O94927,Q13561,O75935,Q15648,P06493,Q8WVM0,Q14203,Q9NVH1,Q9UPT5,Q15691,P24539,Q96A65,P48735,P56385,Q14204
Innate immune system 0.26242404707678446 0.0 1.0 1.0 1.0 278 P25787,P49721,P09601,P06744,P42785,P50570,Q14738,Q13217,P51148,Q9UJV9,P15586,P01889,P11216,Q9Y6G9,P04066,P07948,Q9UQB8,P30519,Q8IV63,P07858,O43242,P18206,P28072,P46940,P11717,Q93050,Q9H7Z7,Q8IV08,P16278,P51812,P61088,P28070,Q13510,Q8WVQ1,Q9BTY2,Q15008,P20618,Q6IAA8,Q96J02,Q9Y487,Q9H0E2,P51665,O43865,Q7L576,O15143,O00584,Q15418,P10253,P35579,P28074,P13473,Q9NZJ7,O00231,O14975,Q96JJ3,Q13464,P63208,P36543,Q9NZ32,Q86VP6,Q15750,P60900,P10619,P42025,Q9Y376,Q14204,Q07065,O00264,O75874
Flt3 signaling in disease 0.2040645771012266 0.0 1.0 1.0 1.0 6 Q01082,Q14789
Synthesis of pyrophosphates in the cytosol -0.3739838669150395 0.0 1.0 1.0 1.0 2 Q9BW91
Pcna dependent long patch base excision repair 0.2762638364694092 0.0 1.0 1.0 1.0 19 Q07864,P18858,P41440
Interferon gamma signaling 0.15737927598321744 0.0 1.0 1.0 1.0 14 P29372
Vegfr2 mediated vascular permeability 0.2258557457212708 0.0 1.0 1.0 1.0 10 P63000,P35222,P07900,O60716,P31751,Q13177,P42345,P35221,Q16512
Regulated necrosis 0.21435572465824562 0.0 1.0 1.0 1.0 15 P07900,Q13546,Q16543,O00560,P41440,O75955
Extension of telomeres 0.22352989702791043 0.0 1.0 1.0 1.0 33 Q9NPE3,P18858,P24941,P41440,P49642,P51530,Q8WVB6
Interaction between l1 and ankyrins -0.28792156240531497 0.0 1.0 1.0 1.0 3 Q12955
Tbc rabgaps 0.20602151119124543 0.0 1.0 1.0 1.0 13 Q15907,P51148,Q4KMP7,P20338,P20339
Signal transduction by l1 0.21351062033582274 0.0 1.0 1.0 1.0 11 P19784,O14786,Q16512,P68400
Signaling by rho gtpases miro gtpases and rhobtb3 0.24231014333583176 0.0 1.0 1.0 1.0 247 Q8NBT2,O15498,Q13017,Q8TAA9,Q14738,Q96EA4,P02786,Q9Y6G9,Q99707,Q9UQB8,P30519,Q92674,O43683,Q86Y07,P50402,P08670,Q9UJF2,P46940,P28288,Q15904,Q9UEY8,Q68EM7,Q13257,Q13505,Q8N6H7,O15173,Q14155,Q14739,Q8NBN3,Q96N67,P51648,Q96HY6,O14578,P51572,Q6IAA8,P35080,Q16543,Q12792,Q7L576,O15143,P41440,O75976,P35580,P35579,O43396,P12814,Q658Y4,Q92974,Q96JJ3,P50748,P52306,P57740,Q13464,P61604,Q9BXS4,Q15691,Q15642,Q8NFH4,O14964,Q9NSV4,Q86XL3,O95202,P38159,Q07065,Q14204,Q13618
Trans golgi network vesicle budding 0.302118909350399 0.0 1.0 1.0 1.0 33 P05067,Q14789,P50570,P11717,O00443,P51148,O95295,P15586,O60749,P02786,P51809,O14964,O75976,O00203,Q00610,Q99523
Rhot1 gtpase cycle -0.4342412335698045 0.0 1.0 1.0 1.0 2 Q8IXI2
Protein ubiquitination 0.2385089841325942 0.0 1.0 1.0 1.0 25 O75150,Q93008,P78527,Q9BUN8,Q6PD62,P50542,Q92541,P61088
Cilium assembly 0.28296039404827755 0.0 1.0 1.0 1.0 55 O75935,Q96KP1,A6NIH7,Q9H6D7,Q9UPT5,Q15691,Q96A65,O94927,P41208,P06493,Q14203,Q13561,Q8TAG9
Slc transporter disorders 0.17832763864529805 0.0 1.0 1.0 1.0 34 Q5SRE5,P57740,Q8TEM1,P35613,P12270,Q92581,Q8NFH4,P53985,P11166,Q92621,Q7Z3B4,Q8N1F7,Q9BTX1
Disorders of transmembrane transporters 0.30506009546186025 0.0 1.0 1.0 1.0 78 P25787,P49721,P35613,Q92621,O43242,P28072,Q06323,P53985,Q7Z3B4,P28070,Q8N1F7,Q9BTX1,Q15008,P20618,P12270,P51665,P11166,P28074,O00231,P57740,Q8NFH4,P60900,Q9BUN8
Signaling by alk in cancer 0.25343356101600545 0.0 1.0 1.0 1.0 34 Q92734,Q14203,P63208,P18206,P12270,P62753,P26038,P67936,P51608,P35579,P19174,Q63HN8,P33176,Q00610
Type i hemidesmosome assembly -0.32195121951219535 0.0 1.0 1.0 1.0 2 Q15149,Q03001
Nuclear events stimulated by alk signaling in cancer 0.18990483283512385 0.0 1.0 1.0 1.0 11 P63208,Q00610,P51608,P62753
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.2724915842089364 0.0 1.0 1.0 1.0 25 P16278,Q9BV10
Signaling by wnt 0.24411900453919164 0.0 1.0 1.0 1.0 90 P49721,O00231,P20618,P28072,P51665,P60900,P63218,P28070,Q9HCE1,P28074
Golgi to er retrograde transport 0.17401802180886788 0.0 1.0 1.0 1.0 70 Q9P2W9,P24390,Q9H0U4,O75935,Q9NZ32,O43731,P61923,Q8N6H7,Q9Y6G9,Q14203,Q14204,Q13561
Er to golgi anterograde transport 0.2931336414262275 0.0 1.0 1.0 1.0 79 O15498,Q15436,P61923,Q9Y6G9,O95249,O15027,Q96PC5,Q9Y296,P83436,O43731,Q8N6H7,Q13561,O95486,P24390,Q14789,O75935,Q12893,Q9UP83,Q9H0U4,Q9NZ32,O60763,Q14203,Q14204
Telomere c strand lagging strand synthesis 0.29258769009609975 0.0 1.0 1.0 1.0 22 P18858,P41440,P49642,P51530,Q8WVB6
Lagging strand synthesis 0.270842068850687 0.0 1.0 1.0 1.0 20 P49642,P18858,P51530,P41440
Recruitment of numa to mitotic centrosomes 0.32549043898331415 0.0 1.0 1.0 1.0 32 O75935,Q9H6D7,Q15691,Q96CW5,O94927,P41208,P06493,Q14203,Q13561
Apoptotic execution phase 0.18678719866115792 0.0 1.0 1.0 1.0 29 Q16625,P51572
Resolution of abasic sites ap sites 0.2567278298473562 0.0 1.0 1.0 1.0 29 P29372,P41440
Dna repair 0.14097042964993536 0.0 1.0 1.0 1.0 116 Q9UNS1,P52292,P78527,P20585,P41208,Q9UNS2,P18858,O00213,P18887,P61201,P61088,Q07864,Q6P6C2,P24941,O96028,Q9BXW9,Q9UQ84,Q9NVI1,P41440,P51530,P35251,P29372,P19447,Q7L5N1,Q99627,P30876,P43246,Q13619,P52701
Oncogenic mapk signaling 0.2614394244243794 0.0 1.0 1.0 1.0 28 P51114,Q9UQ13,P46940,Q6RW13,Q9NRY5
Hdms demethylate histones 0.23291594253355374 0.0 1.0 1.0 1.0 9 Q7LBC6,Q9Y4C1,O75151,P41229,Q8NB78
Base excision repair 0.25178426555318856 0.0 1.0 1.0 1.0 30 P29372,P41440
Translocation of slc2a4 glut4 to the plasma membrane 0.2664397857065507 0.0 1.0 1.0 1.0 31 Q9UIQ6,Q96KP1,Q9UPT5,P11233,Q96A65,P35579,Q8TAG9
Reproduction 0.2550235541358836 0.0 1.0 1.0 1.0 23 Q9UH99,P11802
Regulation of tp53 activity through phosphorylation 0.20671235251106693 0.0 1.0 1.0 1.0 33 P68400,P24941,P54619,Q08945,Q9UQ84,Q9Y3T9,P51530,Q9Y5B9
Intracellular signaling by second messengers 0.27380616052859164 0.0 1.0 1.0 1.0 85 P49721,O00231,P20618,O43242,P28072,O43865,P51665,P60900,P28070,Q9HCE1,P28074
Autophagy 0.32463437400500933 0.0 1.0 1.0 1.0 45 P13473,Q8N4H5,Q14204,Q9NS69,P68400,P07900,P19784,P08670,Q6IAA8,P42345,P54619,Q96E29,P50542,Q9Y6G9,P21796,P61088,Q15388
Resolution of sister chromatid cohesion 0.19786437405798646 0.0 1.0 1.0 1.0 59 Q8NBT2,Q14204,Q96IY1,Q8NFH3,P30154,Q14738,Q14008,Q2NKX8,Q96EA4,Q9Y6G9,Q92674,O43683,Q12769,Q13257,Q96EE3,Q29RF7,Q9Y266,Q12834,Q9UQE7,P06493,P50748,P57740,Q15691,Q8NFH4,Q15005,Q6IPU0
Nuclear envelope ne reassembly 0.2308029700646083 0.0 1.0 1.0 1.0 44 P50402,P06493,Q8IXJ6,Q86XL3,Q92621,Q8N1F7,Q14739,Q9BTX1
Complex i biogenesis 0.29541511687414274 0.0 1.0 1.0 1.0 30 P03886,O75306,O43676,Q9P0J0
Tryptophan catabolism -0.4412151938600222 0.0 1.0 1.0 1.0 2 Q6YP21
Pten regulation 0.3434122399615168 0.0 1.0 1.0 1.0 65 P49721,O00231,P20618,O43242,P28072,P42345,P51665,P60900,P28070,Q9HCE1,P28074
Copi mediated anterograde transport 0.3136435090432942 0.0 1.0 1.0 1.0 56 Q9UP83,O15498,P24390,Q14789,O75935,Q9H0U4,Q9NZ32,P83436,P61923,O43731,O60763,Q12893,Q8N6H7,Q9Y6G9,O95249,Q14203,Q14204,Q13561
Copi dependent golgi to er retrograde traffic 0.2535037357325293 0.0 1.0 1.0 1.0 46 O43731,P24390
Mitotic spindle checkpoint 0.22858100436902706 0.0 1.0 1.0 1.0 57 Q8NBT2,Q14204,Q96IY1,Q8NFH3,P30154,Q14738,Q14008,Q2NKX8,Q96EA4,Q9Y6G9,Q92674,Q9UJX4,O43683,Q12769,Q13257,Q96EE3,Q9Y266,Q13042,Q12834,Q9UJX5,P50748,P57740,Q15691,Q8NFH4,Q9UJX6,Q15005,Q6IPU0
Transport to the golgi and subsequent modification 0.29819208399426606 0.0 1.0 1.0 1.0 81 O15498,Q15436,P61923,P04066,Q9Y6G9,O95249,O15027,Q96PC5,Q9Y296,P83436,O43731,Q8N6H7,Q13561,O95486,P24390,Q14789,O75935,Q12893,Q9UP83,Q9H0U4,Q9NZ32,O60763,Q14203,Q14204
Acyl chain remodelling of pg -0.2905487804878051 0.0 1.0 1.0 1.0 2 Q92604,Q8NF37
Intra golgi and retrograde golgi to er traffic 0.20885660258313152 0.0 1.0 1.0 1.0 87 O60499,O15498,P61923,Q9Y6G9,O95249,O00461,P11717,P83436,O43731,Q8N6H7,Q8TD16,Q13561,P24390,O75935,Q9UP83,Q9P2W9,Q9H0U4,Q9NZ32,Q14203,Q14204
Phosphorylation of the apc c 0.17684831208186463 0.0 1.0 1.0 1.0 13 Q9UJX4,Q13042,Q9UJX2,Q9UJX6,Q9UJX5,P06493
Cell cycle mitotic 0.2836795269227481 0.0 1.0 1.0 1.0 251 P25787,P49721,Q14738,P28072,P28070,Q14739,Q13561,Q07864,Q15008,Q15021,Q96CW5,P41440,P28074,Q9NYZ3,P50748,P57740,P63208,Q9Y619,Q86XL3,Q14203,Q14204,Q6IBW4,Q96EA4,P41208,Q9Y6G9,Q86Y07,Q06323,Q13257,O94927,Q7Z3B4,Q9BTX1,O75935,P20618,P12270,P51665,P49642,P49736,P49841,P51530,P35251,O00231,Q15691,P60900,Q8NBT2,P00374,P07900,P19784,P30154,Q92674,Q9UJX4,P11802,O43242,P18858,Q9Y248,P08238,P25205,Q8N1F7,Q96RT7,Q8NC56,P24941,Q9UJX5,Q9UQE7,Q5SRE5,P33992,P33991,O00487,Q8IXJ6,Q15005,Q92973,Q8TEM1,Q9H6D7,P07948,Q92621,O43683,P68400,P50402,Q29RF7,P06493,Q9H0U4,Q8NFH4,O60763
Meiosis 0.2550235541358836 0.0 1.0 1.0 1.0 23 Q9UH99,P11802
Cell cell communication 0.21876103420974072 0.0 1.0 1.0 1.0 28 Q8N3R9,Q15404
Mitotic prometaphase 0.26608761539262277 0.0 1.0 1.0 1.0 88 Q14204,Q8NBT2,Q15005,P07900,Q96IY1,P19784,Q9H6D7,P30154,Q8NFH3,Q14738,Q14008,Q2NKX8,O95347,Q96EA4,P41208,Q9Y6G9,Q92674,O43683,P68400,Q12769,Q13257,Q96EE3,O94927,Q13561,Q29RF7,Q9Y266,Q9BSJ2,Q96RT7,O75935,Q15021,Q96CW5,Q12834,P67870,Q9UQE7,P06493,P50748,P57740,Q15691,Q8NFH4,Q9NTJ3,Q14203,Q6IPU0
Polymerase switching 0.25870799983395615 0.0 1.0 1.0 1.0 14
Senescence associated secretory phenotype sasp 0.2565672736648453 0.0 1.0 1.0 1.0 22 Q15418,P11802
Tcf dependent signaling in response to wnt 0.3229336684084695 0.0 1.0 1.0 1.0 63 P49721,O00231,P20618,P28072,P51665,P60900,P28070,P28074
Tp53 regulates transcription of dna repair genes 0.2573917489016443 0.0 1.0 1.0 1.0 28 P19447,Q8IXH7,P50750,Q8WX92,P30876,Q9NYV4,Q9BXW9,Q08945,Q9NVI1,Q15369,Q9Y5B9
Regulation of hsf1 mediated heat shock response 0.15453571050644843 0.0 1.0 1.0 1.0 52 O95429,P57740,Q96EB6,P12270,Q8NFH4,Q99543,Q9UL15,Q92621,Q7Z3B4,Q8N1F7,Q9BTX1
Cellular responses to stimuli 0.2015509641946679 0.0 1.0 1.0 1.0 328 P25787,P49721,P09601,P18124,P35611,P40429,P62857,P62081,Q13217,P61353,P61513,Q92621,Q9HCE1,P30519,O75182,P11802,P62841,O95429,P68400,O43242,P28072,Q96EB6,P42766,P43307,P39023,O43731,Q99543,P51812,P28070,Q8N1F7,Q9BTX1,Q13561,O75935,Q15008,P20618,Q6IAA8,P24941,Q92616,P51665,O95070,Q15648,Q15418,P62277,Q9Y241,O14773,P28074,O00231,P13073,P46777,P62269,P57740,P61254,P63208,P62750,P42345,Q9NZ32,P36543,Q8NFH4,P60900,O75880,O76024,Q9UL15,Q14203,Q14204,Q13618,P62847
Mapk family signaling cascades 0.2898763274743572 0.0 1.0 1.0 1.0 89 P49721,O00231,Q14168,O60725,P20618,O43242,P28072,P51665,P60900,P28070,Q9HCE1,P28074
Cs ds degradation -0.38431562954067333 0.0 1.0 1.0 1.0 2 P07686
Dna strand elongation 0.3191120063919545 0.0 1.0 1.0 1.0 30 P35251,P33992,P18858,Q9Y248,P49642,P41440,P25205,P49736,P51530
L1cam interactions 0.23522209473027306 0.0 1.0 1.0 1.0 39 Q96P70,P68400,P19784,P50570,O00560,P26038,Q00610,P51812,Q15418,O14786,P35241,P15311,Q01082
Dna double strand break repair 0.18934415510814478 0.0 1.0 1.0 1.0 57 P35251,Q07864,P51530,Q9UNS1,P24941,O96028,P52292,O00213,P78527,Q9UQ84,P41440,P61088
Regulation of cholesterol biosynthesis by srebp srebf 0.3064499031017286 0.0 1.0 1.0 1.0 27 Q15436,Q9HCL2,Q15648,Q9UBM7,Q16850,Q14534
Homology directed repair 0.294321142500323 0.0 1.0 1.0 1.0 41 Q07864,P51530,Q9UNS1,P24941,O96028,Q9UQ84,P41440,P61088
Nonhomologous end joining nhej 0.27512254901960986 0.0 1.0 1.0 1.0 18 Q9NXR7,P12956,P38398,P49959,P62805,Q9NUW8,P13010,O96028,O95714,P78527,Q14676,Q9NWV8,O95551,O60934,Q12888,P61088,Q92878
Cell cycle 0.25591622316385854 0.0 1.0 1.0 1.0 298 P25787,P49721,Q14738,Q8WXH0,Q9NPE3,P28072,P61088,Q14739,P28070,Q13561,Q07864,Q15008,Q15021,Q96CW5,Q9UQ84,P41440,P28074,Q9NYZ3,P50748,P57740,P63208,Q9Y619,Q9UH99,Q86XL3,Q14203,Q14204,Q6IBW4,Q96EA4,P41208,Q9Y6G9,Q86Y07,Q06323,Q13257,O94927,Q7Z3B4,Q8WVB6,Q9BTX1,O75935,P20618,P12270,P51665,P49642,P49736,P49841,P51530,P35251,O00231,Q15691,P60900,Q8NBT2,P00374,P07900,P19784,P30154,Q92674,Q9UJX4,P11802,O43242,P18858,Q9Y248,P08238,P25205,Q8N1F7,Q96RT7,Q8NC56,P24941,O96028,Q9UJX5,Q9UQE7,Q5SRE5,P33992,P33991,P30876,O00487,Q8IXJ6,Q15005,Q92973,Q8TEM1,Q9H6D7,P07948,Q92621,O43683,P68400,P50402,Q29RF7,P06493,Q9H0U4,Q8NFH4,O60763
Dna damage recognition in gg ner 0.2102457245330956 0.0 1.0 1.0 1.0 18 Q7L5N1,Q9UNS2,Q99627,Q92905,P41208,Q13619,P61201
Formation of incision complex in gg ner 0.22206336416646508 0.0 1.0 1.0 1.0 17 P41208,Q13619,P61088
Nucleotide excision repair 0.17076802697673749 0.0 1.0 1.0 1.0 56 P35251,Q07864,Q7L5N1,P19447,Q99627,Q92905,P61201,Q9HCS7,P30876,P18858,Q13098,P41440,P18887,P41208,Q13619,Q9UNS2,P61088
Nuclear pore complex npc disassembly 0.17344364403486834 0.0 1.0 1.0 1.0 30 Q5SRE5,P57740,Q8TEM1,P06493,P12270,Q8NFH4,Q92621,Q7Z3B4,Q8N1F7,Q9BTX1
Leishmania infection 0.28691271527738843 0.0 1.0 1.0 1.0 37 P09601,O43865,Q7L576,O15143,P63218,P07948,P35579,Q9UQB8
Dual incision in gg ner 0.22740739108517588 0.0 1.0 1.0 1.0 24 Q07864,P19447,Q13619,P41440
Post translational protein modification 0.22452706990615096 0.0 1.0 1.0 1.0 418 P25787,P49721,Q9BTE7,Q9NYU2,P51148,P04844,P21796,Q92541,O60725,P28072,Q02818,Q9Y296,O43731,P16278,P45880,P28070,P61088,Q13561,P24390,Q14789,Q15008,Q92643,Q9ULC3,Q8N4A0,O43852,P28074,O43505,P57740,P63208,Q15750,Q969V5,Q15907,Q9HA64,Q96K76,Q14203,Q14204,Q13618,O15498,Q15436,Q9BV10,Q96GG9,P41208,O95249,Q9Y6G9,Q9UNS2,Q9UKM7,O15027,Q06323,Q8N6H7,Q7Z3B4,Q9BTX1,O75935,P20618,Q13190,P49366,P12270,P51665,Q12893,P61803,Q7L5N1,O00231,Q86YN1,P60900,O14964,Q9H2P9,Q9BUN8,Q15369,Q9Y5A7,Q9Y6K9,Q07065,O60826,O75150,Q93034,Q9Y5P6,P19022,Q15293,P38435,Q13630,P78527,P04066,O43292,Q96PC5,O43242,Q8N1F7,Q9BTY2,Q96FW1,Q8NEZ5,O94952,Q9UP83,O95630,Q13619,Q13217,P61923,Q92621,P83436,Q6PD62,O95486,P53611,P06493,Q99627,Q9H0U4,Q9NZ32,Q86VP6,Q8NFH4,P10619,O60763,O76024,Q15388
Formation of tc ner pre incision complex 0.2905205782277073 0.0 1.0 1.0 1.0 25 Q7L5N1,P19447,Q99627,Q92905,P18074,P61201,P23193,Q9HCS7,P30876,Q13098,Q13619,Q9UNS2
Transcription coupled nucleotide excision repair tc ner 0.23268093864631978 0.0 1.0 1.0 1.0 45 P35251,Q07864,Q7L5N1,P19447,Q99627,Q92905,P61201,Q9HCS7,P30876,P18858,Q13098,P41440,P18887,Q13619,Q9UNS2
Dual incision in tc ner 0.14564993965963624 0.0 1.0 1.0 1.0 33 Q07864,P19447,Q13619,P41440
Copii mediated vesicle transport 0.19483096338127776 0.0 1.0 1.0 1.0 32 O15027,O15498,O95486,Q9H0U4,Q9Y296,Q15436,O60763
Hsf1 dependent transactivation 0.18207996876828014 0.0 1.0 1.0 1.0 15 P42345,P08238,P07900
Srp dependent cotranslational protein targeting to membrane 0.2071691867377357 0.0 1.0 1.0 1.0 91 P67812,P46777,P62269,P62841,P62750,P62857,P62081,P43307,P61353,P61513,P62277,Q15629,P62847
Host interactions of hiv factors 0.27319861811277485 0.0 1.0 1.0 1.0 94 P49721,O00231,Q93034,P20618,O43242,P28072,P51665,P60900,P28070,Q9BTX1,P28074
Cytokine signaling in immune system 0.23035157839287262 0.0 1.0 1.0 1.0 178 P25787,P49721,P09601,Q93034,P07900,P30154,Q14738,P78344,P11233,P01889,P07948,Q92621,Q8IV63,Q13126,O00505,P08670,O43242,P28072,Q06323,P51812,Q7Z3B4,P28070,P61088,Q9BTX1,Q8N1F7,Q04637,Q15008,P20618,P12270,Q9H0E2,P51665,P51809,Q15418,P28074,P61221,P29372,O00231,P57740,P63208,Q15750,Q8NFH4,P60900,Q15369,P26038,Q9Y6K9,Q53EL6
Adaptive immune system 0.24813913602814297 0.0 1.0 1.0 1.0 191 P25787,P49721,Q93034,P50570,Q15436,Q14738,P01889,P07948,Q9UIQ6,P07858,Q9UBS8,Q9NZ08,P28072,O43242,P28070,P61088,Q13561,O95486,Q15008,O75935,P20618,P51572,Q96J02,O43865,P51665,Q8NEZ5,O94952,P28074,O00231,P55786,P63208,Q15386,P42345,Q9NZ32,P60900,P10619,Q9GZZ9,P42025,Q14203,Q14204,Q13618
Cellular response to heat stress 0.15382667267976774 0.0 1.0 1.0 1.0 61 Q5SRE5,O95429,Q8TEM1,P07900,P57740,P42345,Q96EB6,P12270,Q8NFH4,Q13557,Q99543,P08238,P49841,Q9UL15,Q92621,Q7Z3B4,Q8N1F7,Q9BTX1
Dissolution of fibrin clot -0.42195121951219544 0.0 1.0 1.0 1.0 2 P35237,P07355
Global genome nucleotide excision repair gg ner 0.23698881931119092 0.0 1.0 1.0 1.0 43 P35251,Q07864,Q7L5N1,P19447,Q99627,Q92905,P61201,P18858,Q13098,P41440,P18887,P41208,Q13619,Q9UNS2,P61088
Cell surface interactions at the vascular wall 0.2132652411824275 0.0 1.0 1.0 1.0 17 P53985,Q92896,P07948