| term overlap setsize score pval |
| Mitochondrial protein import 5 59 17.28909465020576 2.152023174479761e-05 |
| The citric acid tca cycle and respiratory electron transport 6 160 7.338642489585886 0.0003081932133939 |
| Transport of small molecules 9 377 4.778315217391304 0.0002867206501493 |
| Cholesterol biosynthesis 3 24 25.806122448979597 0.0003416818427961 |
| Protein localization 5 142 6.758583400919167 0.0013363485668772 |
| Formation of atp by chemiosmotic coupling 2 14 29.605263157894736 0.0028647290946027 |
| Metabolism of lipids 9 508 3.476633266533066 0.0023896667480834 |
| Metabolism of steroids 4 103 7.374104683195592 0.0029200061014666 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 4 116 6.509740259740259 0.0044732581954524 |
| Pink1 prkn mediated mitophagy 2 17 23.67719298245614 0.0042338984838508 |
| Digestion and absorption 1 1 inf 0.0057865829735956 |
| Digestion 1 1 inf 0.0057865829735956 |
| Mitochondrial calcium ion transport 2 21 18.685133887349952 0.0064413334274172 |
| Mitophagy 2 24 16.13237639553429 0.0083721819889458 |
| Pyruvate metabolism 2 26 14.785087719298245 0.0097858439890688 |
| Cristae formation 2 27 14.192280701754386 0.0105296929233529 |
| Hdl clearance 1 2 174.75862068965515 0.011540245710655 |
| Scavenging by class b receptors 1 2 174.75862068965515 0.011540245710655 |
| Ub specific processing proteases 4 151 4.942486085343228 0.0111998076642872 |
| Antigen processing cross presentation 3 77 7.284990347490347 0.0099428367068397 |
| Rna polymerase ii transcribes snrna genes 0 73 0.0 1.0 |
| Negative regulation of met activity 0 20 0.0 1.0 |
| Copi mediated anterograde transport 1 89 1.968847962382445 0.404735943393097 |
| Met receptor activation 0 4 0.0 1.0 |
| Formation of the cornified envelope 0 24 0.0 1.0 |
| Signaling by met 0 64 0.0 1.0 |
| Copi dependent golgi to er retrograde traffic 1 83 2.11417157275021 0.3834615031314733 |
| Copi independent golgi to er retrograde traffic 0 45 0.0 1.0 |
| Metabolism of fat soluble vitamins 0 29 0.0 1.0 |
| Regulation of tp53 expression and degradation 0 33 0.0 1.0 |
| Regulation of tp53 activity through methylation 0 16 0.0 1.0 |
| Pten regulation 2 128 2.7878028404344195 0.1691948447040127 |
| Keratinization 0 24 0.0 1.0 |
| Interleukin 6 signaling 0 8 0.0 1.0 |
| Retrograde transport at the trans golgi network 0 49 0.0 1.0 |
| Polymerase switching 0 16 0.0 1.0 |
| Switching of origins to a post replicative state 2 85 4.250264214753752 0.0866491789587889 |
| Dna replication pre initiation 2 92 3.916959064327485 0.0990713387032311 |
| Activation of the pre replicative complex 0 33 0.0 1.0 |
| Dna replication initiation 0 8 0.0 1.0 |
| Orc1 removal from chromatin 2 65 5.610693400167085 0.054278460414587 |
| G2 phase 0 4 0.0 1.0 |
| M phase 2 355 0.9725162765270116 0.6141861309745582 |
| Mitotic telophase cytokinesis 0 13 0.0 1.0 |
| Mitotic prometaphase 0 198 0.0 1.0 |
| Mitotic prophase 0 93 0.0 1.0 |
| Cdt1 association with the cdc6 orc origin complex 2 54 6.804993252361673 0.0388713165501484 |
| Cdc6 association with the orc origin complex 0 12 0.0 1.0 |
| Assembly of the orc complex at the origin of replication 0 20 0.0 1.0 |
| Glycerophospholipid catabolism 0 4 0.0 1.0 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0 27 0.0 1.0 |
| Pi5p regulates tp53 acetylation 0 9 0.0 1.0 |
| Intra golgi and retrograde golgi to er traffic 2 181 1.95197490934039 0.2818399393611144 |
| Regulation of tp53 activity through association with co factors 0 12 0.0 1.0 |
| Intra golgi traffic 1 42 4.2455845248107655 0.2166966342828614 |
| Regulation of tp53 activity through acetylation 0 30 0.0 1.0 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0 18 0.0 1.0 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0 13 0.0 1.0 |
| Trna processing in the mitochondrion 0 5 0.0 1.0 |
| Trna processing in the nucleus 0 60 0.0 1.0 |
| Interleukin 10 signaling 0 6 0.0 1.0 |
| Interleukin 6 family signaling 0 10 0.0 1.0 |
| Fanconi anemia pathway 0 36 0.0 1.0 |
| Synthesis of wybutosine at g37 of trna phe 0 6 0.0 1.0 |
| Trna modification in the nucleus and cytosol 0 43 0.0 1.0 |
| Dual incision in tc ner 0 67 0.0 1.0 |
| Transcription coupled nucleotide excision repair tc ner 0 82 0.0 1.0 |
| Formation of tc ner pre incision complex 0 53 0.0 1.0 |
| Highly calcium permeable nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Highly sodium permeable postsynaptic acetylcholine nicotinic receptors 0 1 0.0 1.0 |
| Presynaptic nicotinic acetylcholine receptors 0 2 0.0 1.0 |
| Inflammasomes 0 12 0.0 1.0 |
| Respiratory electron transport 2 101 3.5576820839978733 0.1157220533027023 |
| Deposition of new cenpa containing nucleosomes at the centromere 0 34 0.0 1.0 |
| Post translational protein modification 6 1003 1.0378304725497247 0.5296102501308463 |
| Dual incision in gg ner 0 42 0.0 1.0 |
| Global genome nucleotide excision repair gg ner 0 87 0.0 1.0 |
| Nucleotide excision repair 0 114 0.0 1.0 |
| Erbb2 regulates cell motility 0 6 0.0 1.0 |
| Regulation of tp53 activity through phosphorylation 0 82 0.0 1.0 |
| Interleukin 4 and interleukin 13 signaling 0 40 0.0 1.0 |
| Gdp fucose biosynthesis 0 6 0.0 1.0 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 0 16 0.0 1.0 |
| Fgfr2 alternative splicing 0 26 0.0 1.0 |
| Tp53 regulates transcription of death receptors and ligands 0 10 0.0 1.0 |
| Tp53 regulates transcription of caspase activators and caspases 0 8 0.0 1.0 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0 11 0.0 1.0 |
| Tp53 regulates transcription of genes involved in cytochrome c release 0 16 0.0 1.0 |
| Antimicrobial peptides 0 7 0.0 1.0 |
| Oncogenic mapk signaling 0 66 0.0 1.0 |
| Ras signaling downstream of nf1 loss of function variants 0 5 0.0 1.0 |
| Signaling by braf and raf1 fusions 0 53 0.0 1.0 |
| Signaling by moderate kinase activity braf mutants 0 36 0.0 1.0 |
| Complex i biogenesis 2 56 6.551656920077972 0.0415275120386823 |
| Neutrophil degranulation 2 319 1.0869444905639494 0.5553061196852187 |
| Choline catabolism 0 4 0.0 1.0 |
| Tp53 regulates transcription of dna repair genes 0 61 0.0 1.0 |
| Protein protein interactions at synapses 0 46 0.0 1.0 |
| Neurexins and neuroligins 0 28 0.0 1.0 |
| Rrna modification in the mitochondrion 0 6 0.0 1.0 |
| Tp53 regulates transcription of cell cycle genes 0 43 0.0 1.0 |
| Rrna modification in the nucleus and cytosol 0 63 0.0 1.0 |
| Il 6 type cytokine receptor ligand interactions 0 6 0.0 1.0 |
| Trna modification in the mitochondrion 0 9 0.0 1.0 |
| Processive synthesis on the lagging strand 0 17 0.0 1.0 |
| Cyclin d associated events in g1 0 45 0.0 1.0 |
| Dna strand elongation 0 35 0.0 1.0 |
| Purine salvage 0 12 0.0 1.0 |
| Ketone body metabolism 0 7 0.0 1.0 |
| Rna polymerase iii transcription 0 44 0.0 1.0 |
| Rna polymerase iii transcription termination 0 24 0.0 1.0 |
| Dna damage reversal 0 8 0.0 1.0 |
| Resolution of abasic sites ap sites 0 41 0.0 1.0 |
| Base excision repair ap site formation 0 23 0.0 1.0 |
| Dna repair 0 291 0.0 1.0 |
| Dna damage bypass 0 49 0.0 1.0 |
| Purine catabolism 0 14 0.0 1.0 |
| Death receptor signalling 0 120 0.0 1.0 |
| Base excision repair 0 55 0.0 1.0 |
| Rna polymerase i transcription 0 63 0.0 1.0 |
| Rna polymerase i transcription termination 0 32 0.0 1.0 |
| Rna polymerase ii transcription 2 969 0.3327346287124222 0.9803673085261492 |
| Rna polymerase ii transcription termination 0 66 0.0 1.0 |
| Purine ribonucleoside monophosphate biosynthesis 0 11 0.0 1.0 |
| Rna polymerase iii chain elongation 0 19 0.0 1.0 |
| Rna polymerase i promoter escape 0 42 0.0 1.0 |
| Rna polymerase i transcription initiation 0 49 0.0 1.0 |
| Chromosome maintenance 0 100 0.0 1.0 |
| Irs activation 0 4 0.0 1.0 |
| Signal attenuation 0 9 0.0 1.0 |
| Insulin receptor signalling cascade 0 31 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0 5 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0 9 0.0 1.0 |
| Synthesis of ketone bodies 0 6 0.0 1.0 |
| Rna polymerase iii transcription initiation from type 3 promoter 0 30 0.0 1.0 |
| Rna polymerase iii transcription initiation from type 1 promoter 0 31 0.0 1.0 |
| Platelet aggregation plug formation 0 20 0.0 1.0 |
| Response to elevated platelet cytosolic ca2 0 71 0.0 1.0 |
| Platelet activation signaling and aggregation 0 152 0.0 1.0 |
| Tnf signaling 0 39 0.0 1.0 |
| Platelet adhesion to exposed collagen 0 7 0.0 1.0 |
| Synthesis of very long chain fatty acyl coas 0 17 0.0 1.0 |
| Dissolution of fibrin clot 0 7 0.0 1.0 |
| Trail signaling 0 6 0.0 1.0 |
| Fasl cd95l signaling 0 5 0.0 1.0 |
| Apoptotic execution phase 0 47 0.0 1.0 |
| Triglyceride biosynthesis 0 7 0.0 1.0 |
| Fatty acyl coa biosynthesis 0 29 0.0 1.0 |
| Mrna editing 0 4 0.0 1.0 |
| Processing of capped intronless pre mrna 0 29 0.0 1.0 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0 14 0.0 1.0 |
| Signaling by insulin receptor 0 45 0.0 1.0 |
| Pyrimidine catabolism 0 6 0.0 1.0 |
| Lagging strand synthesis 0 23 0.0 1.0 |
| Pyrimidine salvage 0 9 0.0 1.0 |
| Translation 0 289 0.0 1.0 |
| Fructose catabolism 0 3 0.0 1.0 |
| Glucose metabolism 1 80 2.1951113051069404 0.3725457481110561 |
| Gluconeogenesis 1 25 7.265086206896552 0.135199366235551 |
| Glycogen breakdown glycogenolysis 0 13 0.0 1.0 |
| Glycolysis 1 66 2.6716180371352785 0.3190412037162214 |
| Cyclin a cdk2 associated events at s phase entry 2 79 4.584187742082479 0.0764185806768525 |
| Cell cycle checkpoints 2 257 1.359752321981424 0.4404100165029421 |
| Mitotic spindle checkpoint 0 111 0.0 1.0 |
| G1 s dna damage checkpoints 2 61 5.993458221825751 0.0484554006127248 |
| Galactose catabolism 0 5 0.0 1.0 |
| Stabilization of p53 2 51 7.2237737200143215 0.0350160011108628 |
| G2 m dna replication checkpoint 0 5 0.0 1.0 |
| G2 m dna damage checkpoint 0 66 0.0 1.0 |
| Dna replication 2 137 2.5996101364522417 0.1878644138631122 |
| Cell cycle mitotic 3 498 1.0435064935064935 0.5555158130133745 |
| Cyclin a b1 b2 associated events during g2 m transition 0 24 0.0 1.0 |
| S phase 2 158 2.2449392712550607 0.2323827916643672 |
| Synthesis of dna 2 117 3.057818459191457 0.1468759864960251 |
| Gap filling dna repair synthesis and ligation in gg ner 0 28 0.0 1.0 |
| G1 s specific transcription 1 29 6.224753694581281 0.1550945129222576 |
| G2 m checkpoints 2 134 2.659489633173844 0.1816063161692526 |
| Urea cycle 0 6 0.0 1.0 |
| Branched chain amino acid catabolism 0 22 0.0 1.0 |
| Histidine catabolism 0 3 0.0 1.0 |
| Recycling of eif2 gdp 0 8 0.0 1.0 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0 59 0.0 1.0 |
| Eukaryotic translation initiation 0 116 0.0 1.0 |
| Rrna processing 0 202 0.0 1.0 |
| Trna processing 0 109 0.0 1.0 |
| Processing of capped intron containing pre mrna 0 239 0.0 1.0 |
| Transport of mature transcript to cytoplasm 0 81 0.0 1.0 |
| Mrna editing c to u conversion 0 2 0.0 1.0 |
| Mrna splicing 0 188 0.0 1.0 |
| Mrna splicing minor pathway 0 52 0.0 1.0 |
| Mrna capping 0 29 0.0 1.0 |
| Pyruvate metabolism and citric acid tca cycle 2 48 7.697177726926011 0.0313211948292666 |
| Citric acid cycle tca cycle 0 21 0.0 1.0 |
| Metabolism of carbohydrates 1 201 0.8566379310344827 0.692139455655399 |
| Ethanol oxidation 0 5 0.0 1.0 |
| Pentose phosphate pathway 0 13 0.0 1.0 |
| Metabolism of amino acids and derivatives 3 281 1.8998586844809864 0.2216933184929663 |
| Creatine metabolism 0 6 0.0 1.0 |
| Tryptophan catabolism 0 6 0.0 1.0 |
| Lysine catabolism 0 11 0.0 1.0 |
| Propionyl coa catabolism 0 5 0.0 1.0 |
| Transport of nucleotide sugars 0 4 0.0 1.0 |
| Formation of incision complex in gg ner 0 42 0.0 1.0 |
| Nonhomologous end joining nhej 0 41 0.0 1.0 |
| Cargo concentration in the er 0 23 0.0 1.0 |
| Piwi interacting rna pirna biogenesis 0 16 0.0 1.0 |
| Metabolic disorders of biological oxidation enzymes 0 13 0.0 1.0 |
| Ion homeostasis 0 31 0.0 1.0 |
| Physiological factors 0 6 0.0 1.0 |
| Transcriptional regulation by small rnas 0 57 0.0 1.0 |
| Phase 2 plateau phase 0 3 0.0 1.0 |
| Phase 0 rapid depolarisation 0 6 0.0 1.0 |
| Cardiac conduction 0 43 0.0 1.0 |
| Phase 3 rapid repolarisation 0 1 0.0 1.0 |
| Ikba variant leads to eda id 0 7 0.0 1.0 |
| Phase 4 resting membrane potential 0 2 0.0 1.0 |
| Organic cation transport 0 3 0.0 1.0 |
| Aflatoxin activation and detoxification 0 6 0.0 1.0 |
| Diseases of mismatch repair mmr 0 5 0.0 1.0 |
| Negative regulation of tcf dependent signaling by dvl interacting proteins 0 5 0.0 1.0 |
| Mitochondrial translation 0 93 0.0 1.0 |
| Ra biosynthesis pathway 0 9 0.0 1.0 |
| Release of hh np from the secreting cell 0 2 0.0 1.0 |
| Signaling by retinoic acid 0 26 0.0 1.0 |
| Mismatch repair 0 17 0.0 1.0 |
| Organic cation anion zwitterion transport 0 3 0.0 1.0 |
| Synthesis of diphthamide eef2 0 8 0.0 1.0 |
| Irak4 deficiency tlr2 4 0 4 0.0 1.0 |
| Clec7a dectin 1 induces nfat activation 0 10 0.0 1.0 |
| Rho gtpases activate pkns 0 40 0.0 1.0 |
| Trafficking of myristoylated proteins to the cilium 1 4 58.241379310344826 0.0229495457607021 |
| Cd209 dc sign signaling 0 18 0.0 1.0 |
| C type lectin receptors clrs 2 100 3.594343000358038 0.1138374922448527 |
| Dectin 2 family 0 4 0.0 1.0 |
| Pyroptosis 0 16 0.0 1.0 |
| Intraflagellar transport 0 48 0.0 1.0 |
| Bbsome mediated cargo targeting to cilium 0 18 0.0 1.0 |
| Cargo trafficking to the periciliary membrane 2 43 8.640136927685067 0.0255379046944718 |
| Dectin 1 mediated noncanonical nf kb signaling 2 53 6.939112487100103 0.0375687779924334 |
| Vxpx cargo targeting to cilium 0 18 0.0 1.0 |
| Disorders of transmembrane transporters 3 115 4.795121173469388 0.0287763339658596 |
| Slc transporter disorders 1 54 3.280416395575797 0.2696291150014086 |
| Abc transporter disorders 2 61 5.993458221825751 0.0484554006127248 |
| Cilium assembly 2 183 1.9300184162062612 0.2861441173312673 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 0 60 0.0 1.0 |
| Hedgehog off state 2 96 3.748786860768944 0.1063833340194844 |
| Degradation of gli1 by the proteasome 2 53 6.939112487100103 0.0375687779924334 |
| Diseases associated with glycosylation precursor biosynthesis 0 16 0.0 1.0 |
| Clec7a dectin 1 signaling 2 85 4.250264214753752 0.0866491789587889 |
| Anchoring of the basal body to the plasma membrane 0 95 0.0 1.0 |
| Signaling by hedgehog 2 122 2.9289473684210527 0.1569437769977569 |
| Hedgehog ligand biogenesis 2 53 6.939112487100103 0.0375687779924334 |
| Tnfr1 induced nfkappab signaling pathway 0 28 0.0 1.0 |
| Interleukin 3 interleukin 5 and gm csf signaling 0 31 0.0 1.0 |
| Wnt5a dependent internalization of fzd4 0 13 0.0 1.0 |
| Defective c1galt1c1 causes tnps 0 2 0.0 1.0 |
| Defective lfng causes scdo3 0 3 0.0 1.0 |
| Defective galnt3 causes hftc 0 1 0.0 1.0 |
| Gpcr ligand binding 1 46 3.8666666666666663 0.2347468088648468 |
| Presynaptic function of kainate receptors 0 13 0.0 1.0 |
| Interconversion of nucleotide di and triphosphates 0 26 0.0 1.0 |
| Signaling by ctnnb1 phospho site mutants 0 15 0.0 1.0 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 0 12 0.0 1.0 |
| Signaling by wnt in cancer 0 25 0.0 1.0 |
| Sumoylation of dna methylation proteins 0 16 0.0 1.0 |
| Repression of wnt target genes 0 13 0.0 1.0 |
| Regulation of fzd by ubiquitination 0 9 0.0 1.0 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 0 24 0.0 1.0 |
| Degradation of dvl 2 50 7.375 0.0337662417981119 |
| Degradation of axin 2 48 7.697177726926011 0.0313211948292666 |
| Sumoylation of dna replication proteins 0 46 0.0 1.0 |
| Asymmetric localization of pcp proteins 2 54 6.804993252361673 0.0388713165501484 |
| Sumoylation of rna binding proteins 0 47 0.0 1.0 |
| Sumoylation of immune response proteins 0 10 0.0 1.0 |
| O linked glycosylation 0 35 0.0 1.0 |
| O glycosylation of tsr domain containing proteins 0 5 0.0 1.0 |
| Uptake and function of anthrax toxins 0 10 0.0 1.0 |
| Regulation of tnfr1 signaling 0 31 0.0 1.0 |
| Programmed cell death 2 179 1.974427594409753 0.2775343196434237 |
| Tnfr1 induced proapoptotic signaling 0 13 0.0 1.0 |
| Caspase activation via extrinsic apoptotic signalling pathway 0 18 0.0 1.0 |
| Signaling by rnf43 mutants 0 4 0.0 1.0 |
| Signaling by lrp5 mutants 0 2 0.0 1.0 |
| Uptake and actions of bacterial toxins 0 23 0.0 1.0 |
| Uptake and function of diphtheria toxin 0 5 0.0 1.0 |
| Dna methylation 0 14 0.0 1.0 |
| N glycan trimming in the er and calnexin calreticulin cycle 0 32 0.0 1.0 |
| Diseases of immune system 0 15 0.0 1.0 |
| Myogenesis 0 22 0.0 1.0 |
| Toxicity of botulinum toxin type d botd 0 3 0.0 1.0 |
| Negative epigenetic regulation of rrna expression 0 61 0.0 1.0 |
| B wich complex positively regulates rrna expression 0 45 0.0 1.0 |
| Positive epigenetic regulation of rrna expression 0 60 0.0 1.0 |
| Miscellaneous transport and binding events 0 17 0.0 1.0 |
| Vegfr2 mediated cell proliferation 0 15 0.0 1.0 |
| Vegfr2 mediated vascular permeability 0 22 0.0 1.0 |
| Regulated necrosis 0 42 0.0 1.0 |
| Ripk1 mediated regulated necrosis 0 26 0.0 1.0 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0 14 0.0 1.0 |
| Rho gtpases activate cit 0 18 0.0 1.0 |
| Rho gtpases activate ktn1 0 11 0.0 1.0 |
| Rho gtpases activate iqgaps 0 26 0.0 1.0 |
| Defective cftr causes cystic fibrosis 2 54 6.804993252361673 0.0388713165501484 |
| Protein repair 0 5 0.0 1.0 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 0 5 0.0 1.0 |
| Negative regulation of mapk pathway 0 36 0.0 1.0 |
| Negative feedback regulation of mapk pathway 0 6 0.0 1.0 |
| Constitutive signaling by akt1 e17k in cancer 0 25 0.0 1.0 |
| Map2k and mapk activation 0 31 0.0 1.0 |
| Raf activation 0 33 0.0 1.0 |
| Tnfs bind their physiological receptors 0 1 0.0 1.0 |
| Lgi adam interactions 0 5 0.0 1.0 |
| Diseases of metabolism 0 131 0.0 1.0 |
| Tnfr2 non canonical nf kb pathway 2 58 6.3164160401002505 0.0442503136637617 |
| Rho gtpases activate rhotekin and rhophilins 0 8 0.0 1.0 |
| Rho gtpases activate formins 0 133 0.0 1.0 |
| Rho gtpases activate wasps and waves 0 33 0.0 1.0 |
| Infectious disease 3 619 0.8280090445269017 0.7036702830752262 |
| Diseases of signal transduction by growth factor receptors and second messengers 2 333 1.039486934859808 0.5789146212606034 |
| Diseases of carbohydrate metabolism 0 23 0.0 1.0 |
| Formation of xylulose 5 phosphate 0 5 0.0 1.0 |
| Metallothioneins bind metals 0 2 0.0 1.0 |
| Rho gtpases activate nadph oxidases 0 13 0.0 1.0 |
| Mapk family signaling cascades 3 212 2.544771018455229 0.1240445307902484 |
| Surfactant metabolism 0 8 0.0 1.0 |
| Map3k8 tpl2 dependent mapk1 3 activation 0 14 0.0 1.0 |
| Processing of dna double strand break ends 0 66 0.0 1.0 |
| Dna double strand break response 0 49 0.0 1.0 |
| Homologous dna pairing and strand exchange 0 41 0.0 1.0 |
| Mitochondrial fatty acid beta oxidation 0 33 0.0 1.0 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 0 26 0.0 1.0 |
| Sensing of dna double strand breaks 0 6 0.0 1.0 |
| Homology directed repair 0 106 0.0 1.0 |
| Resolution of d loop structures 0 32 0.0 1.0 |
| Dna double strand break repair 0 137 0.0 1.0 |
| Cd22 mediated bcr regulation 0 2 0.0 1.0 |
| Metalloprotease dubs 0 20 0.0 1.0 |
| Ovarian tumor domain proteases 0 34 0.0 1.0 |
| Josephin domain dubs 0 9 0.0 1.0 |
| Uch proteinases 2 79 4.584187742082479 0.0764185806768525 |
| Deubiquitination 4 221 3.324675324675325 0.0387066281297414 |
| Diseases associated with surfactant metabolism 0 1 0.0 1.0 |
| Mapk6 mapk4 signaling 2 77 4.707368421052632 0.0731011513393286 |
| Regulation of tlr by endogenous ligand 0 3 0.0 1.0 |
| Hdr through homologous recombination hrr 0 66 0.0 1.0 |
| Hdr through mmej alt nhej 0 11 0.0 1.0 |
| Hdr through single strand annealing ssa 0 35 0.0 1.0 |
| Clec7a inflammasome pathway 0 4 0.0 1.0 |
| Dna damage recognition in gg ner 0 37 0.0 1.0 |
| Response to metal ions 0 5 0.0 1.0 |
| Regulation of ras by gaps 2 57 6.431897926634769 0.0428807024401959 |
| Pi 3k cascade fgfr1 0 8 0.0 1.0 |
| Shc mediated cascade fgfr1 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr1 0 15 0.0 1.0 |
| Phospholipase c mediated cascade fgfr4 0 3 0.0 1.0 |
| Phospholipase c mediated cascade fgfr2 0 3 0.0 1.0 |
| Vesicle mediated transport 5 546 1.6423632504963377 0.2075611011359293 |
| Fructose metabolism 0 5 0.0 1.0 |
| Pcna dependent long patch base excision repair 0 24 0.0 1.0 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0 7 0.0 1.0 |
| Frs mediated fgfr1 signaling 0 9 0.0 1.0 |
| Constitutive signaling by egfrviii 0 14 0.0 1.0 |
| Activation of smo 0 11 0.0 1.0 |
| Tp53 regulates transcription of cell death genes 0 34 0.0 1.0 |
| Regulation of tp53 activity 0 146 0.0 1.0 |
| Hedgehog on state 2 70 5.195562435500516 0.0618854014686512 |
| Ligand receptor interactions 0 2 0.0 1.0 |
| Tp53 regulates metabolic genes 0 84 0.0 1.0 |
| Rho gtpases activate paks 0 19 0.0 1.0 |
| Rho gtpases activate rocks 0 19 0.0 1.0 |
| Tnfr1 mediated ceramide production 0 3 0.0 1.0 |
| Gli proteins bind promoters of hh responsive genes to promote transcription 0 2 0.0 1.0 |
| Pi 3k cascade fgfr2 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr2 0 14 0.0 1.0 |
| Frs mediated fgfr2 signaling 0 9 0.0 1.0 |
| Termination of translesion dna synthesis 0 34 0.0 1.0 |
| Translesion synthesis by polk 0 17 0.0 1.0 |
| Signaling by fgfr1 in disease 0 29 0.0 1.0 |
| Signaling by fgfr4 in disease 0 11 0.0 1.0 |
| Signaling by fgfr2 in disease 0 28 0.0 1.0 |
| Signaling by fgfr4 0 26 0.0 1.0 |
| Signaling by fgfr3 0 27 0.0 1.0 |
| Signaling by fgfr2 0 51 0.0 1.0 |
| Signaling by fgfr1 0 28 0.0 1.0 |
| Negative regulation of fgfr4 signaling 0 17 0.0 1.0 |
| Negative regulation of fgfr3 signaling 0 17 0.0 1.0 |
| Negative regulation of fgfr2 signaling 0 17 0.0 1.0 |
| Negative regulation of fgfr1 signaling 0 17 0.0 1.0 |
| Pi 3k cascade fgfr4 0 8 0.0 1.0 |
| Shc mediated cascade fgfr4 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr4 0 14 0.0 1.0 |
| Frs mediated fgfr4 signaling 0 9 0.0 1.0 |
| Pi 3k cascade fgfr3 0 8 0.0 1.0 |
| Downstream signaling of activated fgfr3 0 14 0.0 1.0 |
| Frs mediated fgfr3 signaling 0 9 0.0 1.0 |
| Shc mediated cascade fgfr3 0 8 0.0 1.0 |
| Fgfrl1 modulation of fgfr1 signaling 0 2 0.0 1.0 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0 4 0.0 1.0 |
| Processing of intronless pre mrnas 0 21 0.0 1.0 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0 5 0.0 1.0 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0 18 0.0 1.0 |
| Foxo mediated transcription of cell death genes 0 12 0.0 1.0 |
| Regulation of localization of foxo transcription factors 0 13 0.0 1.0 |
| Foxo mediated transcription 0 47 0.0 1.0 |
| Chaperone mediated autophagy 0 16 0.0 1.0 |
| Lipophagy 0 8 0.0 1.0 |
| Autophagy 2 130 2.7436951754385963 0.1733154317106306 |
| Hcmv late events 0 62 0.0 1.0 |
| Assembly and cell surface presentation of nmda receptors 0 28 0.0 1.0 |
| Late endosomal microautophagy 0 29 0.0 1.0 |
| Hcmv early events 0 79 0.0 1.0 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0 19 0.0 1.0 |
| Flt3 signaling 0 27 0.0 1.0 |
| Diseases of base excision repair 0 4 0.0 1.0 |
| Negative regulation of notch4 signaling 2 49 7.532661440836133 0.0325345581009106 |
| Class i peroxisomal membrane protein import 0 19 0.0 1.0 |
| Activated ntrk3 signals through pi3k 0 4 0.0 1.0 |
| Transport to the golgi and subsequent modification 1 148 1.1717100633356792 0.5790208759572316 |
| Molybdenum cofactor biosynthesis 0 7 0.0 1.0 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 0 11 0.0 1.0 |
| Hcmv infection 0 102 0.0 1.0 |
| Irak2 mediated activation of tak1 complex 0 9 0.0 1.0 |
| Postmitotic nuclear pore complex npc reformation 0 27 0.0 1.0 |
| Negative regulation of nmda receptor mediated neuronal transmission 0 14 0.0 1.0 |
| Amino acids regulate mtorc1 0 45 0.0 1.0 |
| Response of mtb to phagocytosis 1 20 9.181488203266788 0.1096818429856673 |
| Suppression of phagosomal maturation 0 11 0.0 1.0 |
| Modulation by mtb of host immune system 0 4 0.0 1.0 |
| Prevention of phagosomal lysosomal fusion 0 8 0.0 1.0 |
| Infection with mycobacterium tuberculosis 1 21 8.721551724137932 0.1148438684626223 |
| Suppression of apoptosis 0 6 0.0 1.0 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 0 15 0.0 1.0 |
| Estrogen stimulated signaling through prkcz 0 6 0.0 1.0 |
| Transcriptional regulation of granulopoiesis 0 34 0.0 1.0 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0 11 0.0 1.0 |
| Response of eif2ak4 gcn2 to amino acid deficiency 0 94 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis 0 4 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 0 6 0.0 1.0 |
| Long term potentiation 0 11 0.0 1.0 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 0 20 0.0 1.0 |
| Activation of ampk downstream of nmdars 0 21 0.0 1.0 |
| Activation of rac1 downstream of nmdars 0 6 0.0 1.0 |
| Foxo mediated transcription of cell cycle genes 0 13 0.0 1.0 |
| Regulation of foxo transcriptional activity by acetylation 0 10 0.0 1.0 |
| Constitutive signaling by overexpressed erbb2 0 11 0.0 1.0 |
| Ikk complex recruitment mediated by rip1 0 16 0.0 1.0 |
| Irak1 recruits ikk complex 0 12 0.0 1.0 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0 11 0.0 1.0 |
| Activated ntrk2 signals through fyn 0 4 0.0 1.0 |
| Ngf stimulated transcription 0 22 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose 0 3 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake 0 3 0.0 1.0 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0 26 0.0 1.0 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0 7 0.0 1.0 |
| Activated ntrk2 signals through frs2 and frs3 0 7 0.0 1.0 |
| Activated ntrk2 signals through pi3k 0 4 0.0 1.0 |
| Erythropoietin activates ras 0 11 0.0 1.0 |
| Ntrk2 activates rac1 0 3 0.0 1.0 |
| Erythropoietin activates stat5 0 4 0.0 1.0 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 8 0.0 1.0 |
| Activated ntrk2 signals through ras 0 6 0.0 1.0 |
| Nr1h2 and nr1h3 mediated signaling 0 31 0.0 1.0 |
| Mecp2 regulates transcription factors 0 4 0.0 1.0 |
| Mecp2 regulates transcription of neuronal ligands 0 4 0.0 1.0 |
| Mecp2 regulates neuronal receptors and channels 0 12 0.0 1.0 |
| Regulation of mecp2 expression and activity 0 30 0.0 1.0 |
| Loss of mecp2 binding ability to the ncor smrt complex 0 7 0.0 1.0 |
| Interleukin 21 signaling 0 5 0.0 1.0 |
| Erythropoietin activates phospholipase c gamma plcg 0 5 0.0 1.0 |
| Activated ntrk2 signals through cdk5 0 3 0.0 1.0 |
| Peroxisomal protein import 0 51 0.0 1.0 |
| Tysnd1 cleaves peroxisomal proteins 0 7 0.0 1.0 |
| Ion transport by p type atpases 0 31 0.0 1.0 |
| Negative regulators of ddx58 ifih1 signaling 0 29 0.0 1.0 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0 13 0.0 1.0 |
| Traf6 mediated nf kb activation 0 22 0.0 1.0 |
| Traf6 mediated irf7 activation 0 15 0.0 1.0 |
| Nonsense mediated decay nmd 0 110 0.0 1.0 |
| Traf3 dependent irf activation pathway 0 13 0.0 1.0 |
| Transferrin endocytosis and recycling 1 18 10.26369168356998 0.0992688536094271 |
| Iron uptake and transport 2 38 9.84502923976608 0.0202506024603532 |
| Endosomal sorting complex required for transport escrt 0 30 0.0 1.0 |
| O linked glycosylation of mucins 0 22 0.0 1.0 |
| Interferon signaling 0 128 0.0 1.0 |
| Regulation of ifna signaling 0 8 0.0 1.0 |
| Regulation of signaling by cbl 0 18 0.0 1.0 |
| Interleukin receptor shc signaling 0 14 0.0 1.0 |
| Meiotic recombination 0 31 0.0 1.0 |
| Interferon alpha beta signaling 0 31 0.0 1.0 |
| Rhof gtpase cycle 0 42 0.0 1.0 |
| Activated ntrk3 signals through ras 0 6 0.0 1.0 |
| Signaling by ntrk3 trkc 0 15 0.0 1.0 |
| Blood group systems biosynthesis 0 5 0.0 1.0 |
| Stat5 activation 0 4 0.0 1.0 |
| Interleukin 27 signaling 0 8 0.0 1.0 |
| Alpha protein kinase 1 signaling pathway 0 9 0.0 1.0 |
| Aggrephagy 0 34 0.0 1.0 |
| Regulation of bach1 activity 0 10 0.0 1.0 |
| Heme signaling 0 36 0.0 1.0 |
| Regulation of hmox1 expression and activity 2 58 6.3164160401002505 0.0442503136637617 |
| Cytoprotection by hmox1 3 110 5.021695594125501 0.0256655799200731 |
| Rhobtb gtpase cycle 0 33 0.0 1.0 |
| Flt3 signaling by cbl mutants 0 4 0.0 1.0 |
| Flt3 signaling through src family kinases 0 2 0.0 1.0 |
| Negative regulation of flt3 0 8 0.0 1.0 |
| Rhobtb3 atpase cycle 0 9 0.0 1.0 |
| Sensory perception 0 84 0.0 1.0 |
| Inactivation of csf3 g csf signaling 0 17 0.0 1.0 |
| Signaling by flt3 fusion proteins 0 16 0.0 1.0 |
| Stat5 activation downstream of flt3 itd mutants 0 6 0.0 1.0 |
| Stat3 nuclear events downstream of alk signaling 0 6 0.0 1.0 |
| Alk mutants bind tkis 0 12 0.0 1.0 |
| Signaling by alk in cancer 0 52 0.0 1.0 |
| Rnd1 gtpase cycle 1 36 4.976354679802956 0.1888339602976967 |
| Rnd2 gtpase cycle 1 40 4.464190981432361 0.2075152487282167 |
| Rnd3 gtpase cycle 0 39 0.0 1.0 |
| Translation of sars cov 2 structural proteins 0 41 0.0 1.0 |
| Signaling by flt3 itd and tkd mutants 0 12 0.0 1.0 |
| Maturation of sars cov 2 nucleoprotein 0 13 0.0 1.0 |
| Cellular response to starvation 0 139 0.0 1.0 |
| Miro gtpase cycle 0 8 0.0 1.0 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 0 20 0.0 1.0 |
| Factors involved in megakaryocyte development and platelet production 0 117 0.0 1.0 |
| Kinesins 0 47 0.0 1.0 |
| Antigen presentation folding assembly and peptide loading of class i mhc 0 24 0.0 1.0 |
| Class i mhc mediated antigen processing presentation 3 295 1.8062010763209395 0.2432186250437519 |
| Antigen processing ubiquitination proteasome degradation 3 250 2.145026026604974 0.1757490259107454 |
| Growth hormone receptor signaling 0 15 0.0 1.0 |
| Gaba b receptor activation 0 16 0.0 1.0 |
| Gaba receptor activation 0 18 0.0 1.0 |
| Cellular response to chemical stress 3 133 4.1237637362637365 0.0415552899548786 |
| Serine biosynthesis 0 7 0.0 1.0 |
| Termination of o glycan biosynthesis 0 4 0.0 1.0 |
| Reactions specific to the complex n glycan synthesis pathway 0 6 0.0 1.0 |
| N glycan antennae elongation 0 8 0.0 1.0 |
| N glycan antennae elongation in the medial trans golgi 0 15 0.0 1.0 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 0 10 0.0 1.0 |
| Defective intrinsic pathway for apoptosis 0 24 0.0 1.0 |
| Nuclear events stimulated by alk signaling in cancer 0 17 0.0 1.0 |
| Sensory perception of taste 0 4 0.0 1.0 |
| Signaling by rho gtpases miro gtpases and rhobtb3 2 593 0.5667468162792769 0.8654055807441959 |
| Amyloid fiber formation 0 41 0.0 1.0 |
| Attachment and entry 0 4 0.0 1.0 |
| Maturation of sars cov 2 spike protein 0 24 0.0 1.0 |
| Sars cov 2 infection 0 62 0.0 1.0 |
| Pexophagy 0 9 0.0 1.0 |
| Killing mechanisms 0 9 0.0 1.0 |
| Parasite infection 0 50 0.0 1.0 |
| Fcgr3a mediated il10 synthesis 0 23 0.0 1.0 |
| Selective autophagy 2 67 5.436977058029689 0.0572787602172155 |
| Anti inflammatory response favouring leishmania parasite infection 0 46 0.0 1.0 |
| Cd163 mediating an anti inflammatory response 0 5 0.0 1.0 |
| Sensory processing of sound by outer hair cells of the cochlea 0 25 0.0 1.0 |
| Defective factor viii causes hemophilia a 0 3 0.0 1.0 |
| Signaling by erbb2 ecd mutants 0 15 0.0 1.0 |
| Purinergic signaling in leishmaniasis infection 0 12 0.0 1.0 |
| Signaling by mras complex mutants 0 8 0.0 1.0 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0 17 0.0 1.0 |
| Sensory processing of sound 0 40 0.0 1.0 |
| Leishmania infection 0 110 0.0 1.0 |
| Signaling by mapk mutants 0 4 0.0 1.0 |
| Defects of contact activation system cas and kallikrein kinin system kks 0 5 0.0 1.0 |
| Response of eif2ak1 hri to heme deficiency 0 10 0.0 1.0 |
| Ras processing 1 19 9.692528735632184 0.1044902269271495 |
| N glycan trimming and elongation in the cis golgi 0 4 0.0 1.0 |
| Adora2b mediated anti inflammatory cytokines production 0 30 0.0 1.0 |
| Defective factor ix causes hemophilia b 0 3 0.0 1.0 |
| Sealing of the nuclear envelope ne by escrt iii 0 26 0.0 1.0 |
| Signaling by kit in disease 0 18 0.0 1.0 |
| Defective ripk1 mediated regulated necrosis 0 6 0.0 1.0 |
| Transcriptional regulation of testis differentiation 0 4 0.0 1.0 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 0 20 0.0 1.0 |
| Translation of sars cov 1 structural proteins 0 22 0.0 1.0 |
| Maturation of sars cov 1 spike protein 0 5 0.0 1.0 |
| Maturation of protein 3a 0 5 0.0 1.0 |
| Maturation of sars cov 1 nucleoprotein 0 9 0.0 1.0 |
| Flt3 signaling in disease 0 22 0.0 1.0 |
| Sars cov infections 0 128 0.0 1.0 |
| Translation of replicase and assembly of the replication transcription complex 0 13 0.0 1.0 |
| Potential therapeutics for sars 0 68 0.0 1.0 |
| Sars cov 1 infection 0 42 0.0 1.0 |
| Diseases of dna repair 0 33 0.0 1.0 |
| Diseases of mitotic cell cycle 0 38 0.0 1.0 |
| Nervous system development 2 443 0.771452440625373 0.7331941444917965 |
| Signaling by csf3 g csf 0 22 0.0 1.0 |
| Signaling by membrane tethered fusions of pdgfra or pdgfrb 0 3 0.0 1.0 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0 11 0.0 1.0 |
| Defective f9 activation 0 1 0.0 1.0 |
| Signaling by pdgfr in disease 0 17 0.0 1.0 |
| Inhibition of dna recombination at telomere 0 28 0.0 1.0 |
| Diseases of programmed cell death 0 53 0.0 1.0 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0 6 0.0 1.0 |
| Interleukin 23 signaling 0 5 0.0 1.0 |
| Interleukin 12 signaling 1 38 4.706430568499534 0.1982280898426024 |
| Transcriptional regulation by runx2 2 100 3.594343000358038 0.1138374922448527 |
| Transcriptional regulation by runx3 2 86 4.199248120300752 0.0883929394465974 |
| Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 0 3 0.0 1.0 |
| Protein methylation 0 16 0.0 1.0 |
| Inla mediated entry of listeria monocytogenes into host cells 0 9 0.0 1.0 |
| Listeria monocytogenes entry into host cells 0 21 0.0 1.0 |
| Rab gefs exchange gtp for gdp on rabs 0 79 0.0 1.0 |
| Met promotes cell motility 0 29 0.0 1.0 |
| Met receptor recycling 0 10 0.0 1.0 |
| Transcriptional regulation by runx1 2 149 2.3845327604726103 0.2131779508921852 |
| Met activates rap1 and rac1 0 11 0.0 1.0 |
| Inlb mediated entry of listeria monocytogenes into host cell 0 15 0.0 1.0 |
| Creb3 factors activate genes 0 3 0.0 1.0 |
| Met activates ptk2 signaling 0 19 0.0 1.0 |
| Rab geranylgeranylation 0 54 0.0 1.0 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0 5 0.0 1.0 |
| Rrna processing in the mitochondrion 0 10 0.0 1.0 |
| Tfap2 ap 2 family regulates transcription of cell cycle factors 0 5 0.0 1.0 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 0 7 0.0 1.0 |
| Activation of the tfap2 ap 2 family of transcription factors 0 8 0.0 1.0 |
| Met interacts with tns proteins 0 4 0.0 1.0 |
| Negative regulation of activity of tfap2 ap 2 family transcription factors 0 7 0.0 1.0 |
| Gaba synthesis release reuptake and degradation 0 12 0.0 1.0 |
| Regulation of runx1 expression and activity 0 17 0.0 1.0 |
| Regulation of runx3 expression and activity 2 52 7.07859649122807 0.0362835933613397 |
| Runx3 regulates notch signaling 0 11 0.0 1.0 |
| Runx3 regulates cdkn1a transcription 0 7 0.0 1.0 |
| Runx2 regulates genes involved in cell migration 0 5 0.0 1.0 |
| Runx2 regulates bone development 0 26 0.0 1.0 |
| Runx2 regulates chondrocyte maturation 0 3 0.0 1.0 |
| Runx2 regulates osteoblast differentiation 0 20 0.0 1.0 |
| Regulation of runx2 expression and activity 2 61 5.993458221825751 0.0484554006127248 |
| Runx1 regulates transcription of genes involved in wnt signaling 0 3 0.0 1.0 |
| Runx1 regulates estrogen receptor mediated transcription 0 5 0.0 1.0 |
| Runx1 regulates transcription of genes involved in interleukin signaling 0 4 0.0 1.0 |
| Runx1 regulates transcription of genes involved in bcr signaling 0 4 0.0 1.0 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0 36 0.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of keratinocytes 0 4 0.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 2 68 5.354066985645933 0.0588003571543418 |
| Esr mediated signaling 0 136 0.0 1.0 |
| Aryl hydrocarbon receptor signalling 0 7 0.0 1.0 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0 39 0.0 1.0 |
| Runx1 regulates expression of components of tight junctions 0 4 0.0 1.0 |
| Receptor mediated mitophagy 0 10 0.0 1.0 |
| Runx1 regulates transcription of genes involved in differentiation of myeloid cells 0 5 0.0 1.0 |
| E3 ubiquitin ligases ubiquitinate target proteins 0 40 0.0 1.0 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 0 26 0.0 1.0 |
| Vldlr internalisation and degradation 0 9 0.0 1.0 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 0 13 0.0 1.0 |
| Ptk6 regulates cell cycle 0 5 0.0 1.0 |
| Ptk6 regulates rtks and their effectors akt1 and dok1 0 7 0.0 1.0 |
| Ptk6 regulates proteins involved in rna processing 0 3 0.0 1.0 |
| Wax and plasmalogen biosynthesis 0 5 0.0 1.0 |
| Signaling by ptk6 0 36 0.0 1.0 |
| Erbb2 activates ptk6 signaling 0 3 0.0 1.0 |
| Gastrin creb signalling pathway via pkc and mapk 0 14 0.0 1.0 |
| Transport of organic anions 0 3 0.0 1.0 |
| Ptk6 expression 0 2 0.0 1.0 |
| Advanced glycosylation endproduct receptor signaling 0 9 0.0 1.0 |
| Interferon gamma signaling 0 51 0.0 1.0 |
| The nlrp3 inflammasome 0 10 0.0 1.0 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0 8 0.0 1.0 |
| Transport of fatty acids 0 3 0.0 1.0 |
| Thrombin signalling through proteinase activated receptors pars 0 21 0.0 1.0 |
| Slbp dependent processing of replication dependent histone pre mrnas 0 10 0.0 1.0 |
| Insulin receptor recycling 0 15 0.0 1.0 |
| Beta oxidation of butanoyl coa to acetyl coa 0 5 0.0 1.0 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0 5 0.0 1.0 |
| Regulation of ifng signaling 0 10 0.0 1.0 |
| Synaptic adhesion like molecules 0 11 0.0 1.0 |
| Phosphate bond hydrolysis by ntpdase proteins 0 4 0.0 1.0 |
| Butyrophilin btn family interactions 0 5 0.0 1.0 |
| Vldl assembly 0 3 0.0 1.0 |
| Reelin signalling pathway 0 3 0.0 1.0 |
| Met activates ptpn11 0 5 0.0 1.0 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0 27 0.0 1.0 |
| Downregulation of erbb2 signaling 0 18 0.0 1.0 |
| Ptk6 promotes hif1a stabilization 0 2 0.0 1.0 |
| Clathrin mediated endocytosis 1 119 1.4639099941554647 0.5007471980606311 |
| Cargo recognition for clathrin mediated endocytosis 1 78 2.252575011195701 0.3651632608140126 |
| Golgi to er retrograde transport 1 115 1.515880217785844 0.4888846802698797 |
| Interleukin 20 family signaling 0 11 0.0 1.0 |
| Aurka activation by tpx2 0 73 0.0 1.0 |
| Tbc rabgaps 0 39 0.0 1.0 |
| Transcriptional regulation by ventx 0 37 0.0 1.0 |
| Ret signaling 0 26 0.0 1.0 |
| Signaling by fgfr3 fusions in cancer 0 10 0.0 1.0 |
| Signaling by mst1 0 3 0.0 1.0 |
| The role of gtse1 in g2 m progression after g2 checkpoint 2 67 5.436977058029689 0.0572787602172155 |
| Protein ubiquitination 0 58 0.0 1.0 |
| Met activates pi3k akt signaling 0 6 0.0 1.0 |
| Met activates ras signaling 0 11 0.0 1.0 |
| Signaling by fgfr2 iiia tm 0 18 0.0 1.0 |
| Regulation of pten mrna translation 0 9 0.0 1.0 |
| Interleukin 1 signaling 2 82 4.4109649122807015 0.0814830850630918 |
| Regulation of pten gene transcription 0 56 0.0 1.0 |
| Competing endogenous rnas cernas regulate pten translation 0 8 0.0 1.0 |
| Rhoq gtpase cycle 1 59 2.9961355529131986 0.2906317425239585 |
| Rhod gtpase cycle 0 50 0.0 1.0 |
| Rac2 gtpase cycle 1 81 2.167456896551724 0.3762052776550226 |
| Rac1 gtpase cycle 1 152 1.1402146608814798 0.5888232258810979 |
| Cdc42 gtpase cycle 1 134 1.2968628467721026 0.5428693236699991 |
| Rhoc gtpase cycle 1 75 2.3445945945945947 0.3539291556390659 |
| Rhob gtpase cycle 1 69 2.5529918864097363 0.3308714932126429 |
| Rho gtpase cycle 2 387 0.8887673729778993 0.6614925881036211 |
| Signaling by notch3 0 35 0.0 1.0 |
| Rhoh gtpase cycle 1 32 5.620689655172414 0.1697199333458323 |
| Robo receptors bind akap5 0 8 0.0 1.0 |
| Calnexin calreticulin cycle 0 23 0.0 1.0 |
| Er quality control compartment erqc 0 18 0.0 1.0 |
| Extra nuclear estrogen signaling 0 47 0.0 1.0 |
| Interleukin 37 signaling 0 12 0.0 1.0 |
| Rab regulation of trafficking 0 107 0.0 1.0 |
| Signaling by tgfb family members 0 79 0.0 1.0 |
| Signaling by receptor tyrosine kinases 0 344 0.0 1.0 |
| Signaling by nuclear receptors 0 178 0.0 1.0 |
| Intracellular signaling by second messengers 2 233 1.5046707678286626 0.391920617343827 |
| Regulation of expression of slits and robos 2 155 2.289645682834537 0.2259653618722221 |
| Signaling by erythropoietin 0 19 0.0 1.0 |
| Rhog gtpase cycle 1 71 2.4795566502463053 0.338645862444495 |
| Rhobtb2 gtpase cycle 0 22 0.0 1.0 |
| Interleukin 2 signaling 0 5 0.0 1.0 |
| Biosynthesis of maresins 0 1 0.0 1.0 |
| Biosynthesis of epa derived spms 0 3 0.0 1.0 |
| Biosynthesis of specialized proresolving mediators spms 0 6 0.0 1.0 |
| Estrogen dependent gene expression 0 90 0.0 1.0 |
| Noncanonical activation of notch3 0 8 0.0 1.0 |
| Interleukin 36 pathway 0 1 0.0 1.0 |
| Ticam1 traf6 dependent induction of tak1 complex 0 10 0.0 1.0 |
| Ticam1 dependent activation of irf3 irf7 0 10 0.0 1.0 |
| Rhoj gtpase cycle 1 55 3.219348659003832 0.2738779694784634 |
| Tlr3 mediated ticam1 dependent programmed cell death 0 5 0.0 1.0 |
| Notch4 intracellular domain regulates transcription 0 15 0.0 1.0 |
| Signaling by notch4 2 71 5.119755911517926 0.0634484369785551 |
| Notch3 intracellular domain regulates transcription 0 18 0.0 1.0 |
| Notch3 activation and transmission of signal to the nucleus 0 18 0.0 1.0 |
| Rhot1 gtpase cycle 0 5 0.0 1.0 |
| Rhov gtpase cycle 0 35 0.0 1.0 |
| Rac3 gtpase cycle 1 83 2.11417157275021 0.3834615031314733 |
| Rhobtb1 gtpase cycle 0 22 0.0 1.0 |
| Rhou gtpase cycle 0 39 0.0 1.0 |
| Notch4 activation and transmission of signal to the nucleus 0 8 0.0 1.0 |
| Signaling by ntrk2 trkb 0 18 0.0 1.0 |
| Loss of function of mecp2 in rett syndrome 0 12 0.0 1.0 |
| Transcriptional regulation by mecp2 0 45 0.0 1.0 |
| Aspartate and asparagine metabolism 0 7 0.0 1.0 |
| Phenylalanine and tyrosine metabolism 0 6 0.0 1.0 |
| Tyrosine catabolism 0 2 0.0 1.0 |
| Nucleotide salvage 0 20 0.0 1.0 |
| Nucleotide biosynthesis 0 16 0.0 1.0 |
| Nucleotide catabolism 0 22 0.0 1.0 |
| Carboxyterminal post translational modifications of tubulin 0 25 0.0 1.0 |
| Cellular responses to stimuli 3 614 0.835223287350947 0.6983469441568111 |
| Metabolism of rna 3 647 0.7896794587400178 0.7322017742250595 |
| Chylomicron assembly 0 5 0.0 1.0 |
| Transcriptional regulation by e2f6 0 34 0.0 1.0 |
| Runx3 regulates p14 arf 0 11 0.0 1.0 |
| Runx3 regulates yap1 mediated transcription 0 6 0.0 1.0 |
| Neddylation 2 185 1.9085418464193271 0.2904463217301052 |
| Runx3 regulates wnt signaling 0 8 0.0 1.0 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 1 33 5.444504310344827 0.1745395441217663 |
| Processing of smdt1 0 16 0.0 1.0 |
| Runx3 regulates immune response and cell migration 0 4 0.0 1.0 |
| Regulation of pten stability and activity 2 63 5.795800977854472 0.0513367662234036 |
| Regulation of pten localization 0 8 0.0 1.0 |
| Runx3 regulates bcl2l11 bim transcription 0 5 0.0 1.0 |
| Assembly of active lpl and lipc lipase complexes 0 7 0.0 1.0 |
| Hdl assembly 0 6 0.0 1.0 |
| Plasma lipoprotein assembly 0 12 0.0 1.0 |
| Interleukin 9 signaling 0 4 0.0 1.0 |
| Interleukin 35 signalling 0 9 0.0 1.0 |
| Oas antiviral response 0 6 0.0 1.0 |
| Interleukin 15 signaling 0 8 0.0 1.0 |
| Glycogen metabolism 0 20 0.0 1.0 |
| Rhoa gtpase cycle 2 134 2.659489633173844 0.1816063161692526 |
| Triglyceride metabolism 0 20 0.0 1.0 |
| Metabolism of cofactors 1 15 12.466748768472906 0.0834245093904444 |
| Fatty acid metabolism 2 117 3.057818459191457 0.1468759864960251 |
| G beta gamma signalling through cdc42 0 14 0.0 1.0 |
| Lipid particle organization 0 1 0.0 1.0 |
| Glutamate and glutamine metabolism 0 14 0.0 1.0 |
| Phenylalanine metabolism 0 4 0.0 1.0 |
| Hdl remodeling 0 3 0.0 1.0 |
| Vldl clearance 0 4 0.0 1.0 |
| Plasma lipoprotein clearance 1 23 7.927115987460815 0.1250798098274735 |
| Ldl remodeling 0 2 0.0 1.0 |
| Ldl clearance 0 17 0.0 1.0 |
| Chylomicron clearance 0 4 0.0 1.0 |
| Chylomicron remodeling 0 4 0.0 1.0 |
| Plasma lipoprotein remodeling 0 12 0.0 1.0 |
| Collagen chain trimerization 0 13 0.0 1.0 |
| Sumoylation of chromatin organization proteins 0 58 0.0 1.0 |
| Activation of kainate receptors upon glutamate binding 0 16 0.0 1.0 |
| Mitotic g2 g2 m phases 2 186 1.8979786422578184 0.2925965209489122 |
| Gab1 signalosome 0 10 0.0 1.0 |
| Darpp 32 events 0 20 0.0 1.0 |
| Srp dependent cotranslational protein targeting to membrane 0 108 0.0 1.0 |
| Apc cdc20 mediated degradation of nek2a 0 25 0.0 1.0 |
| Chondroitin sulfate dermatan sulfate metabolism 0 32 0.0 1.0 |
| Signaling by egfr 0 40 0.0 1.0 |
| Retrograde neurotrophin signalling 0 12 0.0 1.0 |
| Interactions of rev with host cellular proteins 0 37 0.0 1.0 |
| Unwinding of dna 0 12 0.0 1.0 |
| Shc1 events in egfr signaling 0 7 0.0 1.0 |
| Phosphorylation of emi1 0 6 0.0 1.0 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0 20 0.0 1.0 |
| Activation of atr in response to replication stress 0 38 0.0 1.0 |
| Interactions of vpr with host cellular proteins 0 37 0.0 1.0 |
| Assembly of the hiv virion 0 15 0.0 1.0 |
| Plasma lipoprotein assembly remodeling and clearance 1 40 4.464190981432361 0.2075152487282167 |
| Activation of c3 and c5 0 1 0.0 1.0 |
| Telomere c strand synthesis initiation 0 13 0.0 1.0 |
| Telomere c strand lagging strand synthesis 0 37 0.0 1.0 |
| Processive synthesis on the c strand of the telomere 0 21 0.0 1.0 |
| Phosphorylation of the apc c 0 20 0.0 1.0 |
| Polymerase switching on the c strand of the telomere 0 28 0.0 1.0 |
| Apobec3g mediated resistance to hiv 1 infection 0 4 0.0 1.0 |
| Extension of telomeres 0 52 0.0 1.0 |
| Ngf independant trka activation 0 1 0.0 1.0 |
| Activation of trka receptors 0 1 0.0 1.0 |
| Signaling by pdgf 0 35 0.0 1.0 |
| Downstream signal transduction 0 23 0.0 1.0 |
| Regulation of beta cell development 0 22 0.0 1.0 |
| Synthesis of ip3 and ip4 in the cytosol 0 20 0.0 1.0 |
| Synthesis of ip2 ip and ins in the cytosol 0 12 0.0 1.0 |
| Synthesis of pyrophosphates in the cytosol 0 10 0.0 1.0 |
| Organelle biogenesis and maintenance 4 268 2.7198347107438017 0.0690665526821041 |
| Nuclear import of rev protein 0 34 0.0 1.0 |
| Fgfr2 mutant receptor activation 0 18 0.0 1.0 |
| Signaling by cytosolic fgfr1 fusion mutants 0 18 0.0 1.0 |
| Cytosolic sensors of pathogen associated dna 0 56 0.0 1.0 |
| Sting mediated induction of host immune responses 0 10 0.0 1.0 |
| Egfr downregulation 0 22 0.0 1.0 |
| Nef mediated cd8 down regulation 0 6 0.0 1.0 |
| Acetylcholine binding and downstream events 0 2 0.0 1.0 |
| Norepinephrine neurotransmitter release cycle 0 12 0.0 1.0 |
| Serotonin neurotransmitter release cycle 0 14 0.0 1.0 |
| Rip mediated nfkb activation via zbp1 0 16 0.0 1.0 |
| Fgfr1 mutant receptor activation 0 22 0.0 1.0 |
| Glutathione synthesis and recycling 0 8 0.0 1.0 |
| Transport and synthesis of paps 0 4 0.0 1.0 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 2 68 5.354066985645933 0.0588003571543418 |
| The fatty acid cycling model 0 1 0.0 1.0 |
| Nef mediated cd4 down regulation 0 7 0.0 1.0 |
| Hiv elongation arrest and recovery 0 32 0.0 1.0 |
| Abortive elongation of hiv 1 transcript in the absence of tat 0 23 0.0 1.0 |
| Transcription of the hiv genome 0 67 0.0 1.0 |
| Hiv transcription elongation 0 42 0.0 1.0 |
| Hiv transcription initiation 0 45 0.0 1.0 |
| Signalling to ras 0 16 0.0 1.0 |
| Terminal pathway of complement 0 1 0.0 1.0 |
| Trafficking and processing of endosomal tlr 0 8 0.0 1.0 |
| Initial triggering of complement 0 1 0.0 1.0 |
| Signaling by ntrks 0 102 0.0 1.0 |
| The activation of arylsulfatases 0 8 0.0 1.0 |
| Mtorc1 mediated signalling 0 23 0.0 1.0 |
| Mitochondrial uncoupling 0 1 0.0 1.0 |
| Myd88 independent tlr4 cascade 0 78 0.0 1.0 |
| Glycosphingolipid metabolism 0 33 0.0 1.0 |
| Sphingolipid de novo biosynthesis 1 29 6.224753694581281 0.1550945129222576 |
| Synthesis of pips at the late endosome membrane 0 10 0.0 1.0 |
| Synthesis of pips at the early endosome membrane 0 16 0.0 1.0 |
| Complement cascade 0 10 0.0 1.0 |
| Toll like receptor 9 tlr9 cascade 0 75 0.0 1.0 |
| Toll like receptor tlr1 tlr2 cascade 0 70 0.0 1.0 |
| Innate immune system 4 624 1.1163636363636364 0.491519229906368 |
| Apc c mediated degradation of cell cycle proteins 2 81 4.467244059515878 0.0797833846389109 |
| Apc c cdc20 mediated degradation of cyclin b 0 23 0.0 1.0 |
| Alternative complement activation 0 1 0.0 1.0 |
| Telomere extension by telomerase 0 21 0.0 1.0 |
| P38mapk events 0 13 0.0 1.0 |
| Arms mediated activation 0 5 0.0 1.0 |
| Signaling by tgf beta receptor complex 0 67 0.0 1.0 |
| Regulation of glucokinase by glucokinase regulatory protein 0 31 0.0 1.0 |
| Adenylate cyclase inhibitory pathway 0 6 0.0 1.0 |
| Adenylate cyclase activating pathway 0 3 0.0 1.0 |
| Prolonged erk activation events 0 12 0.0 1.0 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 0 57 0.0 1.0 |
| Ticam1 rip1 mediated ikk complex recruitment 0 16 0.0 1.0 |
| Toll like receptor cascades 0 103 0.0 1.0 |
| Neurotoxicity of clostridium toxins 0 8 0.0 1.0 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0 42 0.0 1.0 |
| Nod1 2 signaling pathway 0 30 0.0 1.0 |
| Viral messenger rna synthesis 0 44 0.0 1.0 |
| Ns1 mediated effects on host pathways 0 40 0.0 1.0 |
| Export of viral ribonucleoproteins from nucleus 0 32 0.0 1.0 |
| Influenza infection 0 150 0.0 1.0 |
| Scf skp2 mediated degradation of p27 p21 2 54 6.804993252361673 0.0388713165501484 |
| Signalling to erks 0 30 0.0 1.0 |
| Signalling to p38 via rit and rin 0 3 0.0 1.0 |
| Cellular hexose transport 0 6 0.0 1.0 |
| Trans golgi network vesicle budding 1 69 2.5529918864097363 0.3308714932126429 |
| Membrane trafficking 4 532 1.3235537190082645 0.370782647004574 |
| Er to golgi anterograde transport 1 129 1.3481950431034482 0.5292321784755691 |
| Creb phosphorylation 0 7 0.0 1.0 |
| Negative regulation of the pi3k akt network 0 62 0.0 1.0 |
| Vitamin b5 pantothenate metabolism 0 13 0.0 1.0 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0 26 0.0 1.0 |
| Erk mapk targets 0 20 0.0 1.0 |
| Nuclear events kinase and transcription factor activation 0 42 0.0 1.0 |
| Carnitine metabolism 1 12 15.871473354231975 0.0673062601152012 |
| Akt phosphorylates targets in the nucleus 0 9 0.0 1.0 |
| Pi3k akt activation 0 7 0.0 1.0 |
| Signaling by notch2 0 22 0.0 1.0 |
| Signaling by notch1 0 56 0.0 1.0 |
| Nicotinamide salvaging 0 11 0.0 1.0 |
| A tetrasaccharide linker sequence is required for gag synthesis 0 16 0.0 1.0 |
| Metabolism of vitamins and cofactors 1 134 1.2968628467721026 0.5428693236699991 |
| Metabolism of water soluble vitamins and cofactors 1 91 1.924712643678161 0.4116657540066248 |
| Vitamin b2 riboflavin metabolism 0 4 0.0 1.0 |
| Vitamin c ascorbate metabolism 0 6 0.0 1.0 |
| Akt phosphorylates targets in the cytosol 0 14 0.0 1.0 |
| Signaling by bmp 0 15 0.0 1.0 |
| Signaling by alk 0 19 0.0 1.0 |
| Tcf dependent signaling in response to wnt 2 142 2.505513784461153 0.1983619083490726 |
| Fcgr activation 0 5 0.0 1.0 |
| Fcgamma receptor fcgr dependent phagocytosis 0 72 0.0 1.0 |
| Signaling by hippo 0 21 0.0 1.0 |
| Cell surface interactions at the vascular wall 1 70 2.5157421289355324 0.3347698423679039 |
| Erks are inactivated 0 11 0.0 1.0 |
| Calcineurin activates nfat 0 8 0.0 1.0 |
| Generation of second messenger molecules 0 11 0.0 1.0 |
| Cs ds degradation 0 7 0.0 1.0 |
| Hs gag degradation 0 17 0.0 1.0 |
| Tcr signaling 2 85 4.250264214753752 0.0866491789587889 |
| Hs gag biosynthesis 0 17 0.0 1.0 |
| Dermatan sulfate biosynthesis 0 6 0.0 1.0 |
| Chondroitin sulfate biosynthesis 0 12 0.0 1.0 |
| Keratan sulfate degradation 0 6 0.0 1.0 |
| Keratan sulfate biosynthesis 0 11 0.0 1.0 |
| Metabolism of angiotensinogen to angiotensins 0 8 0.0 1.0 |
| Assembly of collagen fibrils and other multimeric structures 0 28 0.0 1.0 |
| Metabolism of nitric oxide nos3 activation and regulation 0 10 0.0 1.0 |
| G protein activation 0 13 0.0 1.0 |
| Formation of the beta catenin tcf transactivating complex 0 38 0.0 1.0 |
| Wnt mediated activation of dvl 0 8 0.0 1.0 |
| Vitamin b1 thiamin metabolism 0 5 0.0 1.0 |
| Synthesis of pips at the golgi membrane 0 15 0.0 1.0 |
| Nicotinate metabolism 0 18 0.0 1.0 |
| Coenzyme a biosynthesis 0 8 0.0 1.0 |
| Synthesis of bile acids and bile salts 0 20 0.0 1.0 |
| Snrnp assembly 0 53 0.0 1.0 |
| Pre notch expression and processing 0 50 0.0 1.0 |
| Pre notch processing in golgi 0 13 0.0 1.0 |
| Pre notch processing in the endoplasmic reticulum 0 5 0.0 1.0 |
| Gap junction degradation 0 12 0.0 1.0 |
| Transport of connexons to the plasma membrane 0 14 0.0 1.0 |
| Gap junction assembly 0 15 0.0 1.0 |
| Fgfr2b ligand binding and activation 0 2 0.0 1.0 |
| Androgen biosynthesis 0 2 0.0 1.0 |
| Fgfr2c ligand binding and activation 0 2 0.0 1.0 |
| Fgfr3b ligand binding and activation 0 1 0.0 1.0 |
| Fgfr1b ligand binding and activation 0 2 0.0 1.0 |
| Fgfr1 ligand binding and activation 0 2 0.0 1.0 |
| Fgfr2 ligand binding and activation 0 2 0.0 1.0 |
| Fgfr3 ligand binding and activation 0 3 0.0 1.0 |
| Signaling by fgfr 0 57 0.0 1.0 |
| Heme degradation 1 7 29.11206896551724 0.0398211631657538 |
| Heme biosynthesis 0 12 0.0 1.0 |
| Metabolism of porphyrins 1 17 10.90625 0.0940175554244995 |
| Fgfr1c ligand binding and activation 0 2 0.0 1.0 |
| Estrogen biosynthesis 0 2 0.0 1.0 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0 13 0.0 1.0 |
| P75ntr signals via nf kb 0 14 0.0 1.0 |
| Biotin transport and metabolism 0 11 0.0 1.0 |
| Metabolism of folate and pterines 1 15 12.466748768472906 0.0834245093904444 |
| Cobalamin cbl vitamin b12 transport and metabolism 0 13 0.0 1.0 |
| Pi3k events in erbb2 signaling 0 7 0.0 1.0 |
| Grb2 events in erbb2 signaling 0 7 0.0 1.0 |
| Beta catenin phosphorylation cascade 0 16 0.0 1.0 |
| Pregnenolone biosynthesis 1 8 24.95073891625616 0.0453811348395634 |
| Metabolism of steroid hormones 1 12 15.871473354231975 0.0673062601152012 |
| Signaling by wnt 2 213 1.6506194395942462 0.350199617154011 |
| Rho gtpase effectors 0 246 0.0 1.0 |
| Degradation of beta catenin by the destruction complex 2 77 4.707368421052632 0.0731011513393286 |
| Vegf ligand receptor interactions 0 2 0.0 1.0 |
| Signaling by vegf 0 87 0.0 1.0 |
| Bile acid and bile salt metabolism 0 22 0.0 1.0 |
| Synthesis of bile acids and bile salts via 27 hydroxycholesterol 0 7 0.0 1.0 |
| Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0 5 0.0 1.0 |
| P75 ntr receptor mediated signalling 0 81 0.0 1.0 |
| P75ntr regulates axonogenesis 0 5 0.0 1.0 |
| Regulated proteolysis of p75ntr 0 11 0.0 1.0 |
| P75ntr negatively regulates cell cycle via sc1 0 5 0.0 1.0 |
| Nrage signals death through jnk 0 47 0.0 1.0 |
| Vitamin d calciferol metabolism 0 8 0.0 1.0 |
| Role of phospholipids in phagocytosis 0 16 0.0 1.0 |
| Synthesis of pips at the plasma membrane 0 47 0.0 1.0 |
| Mtor signalling 0 39 0.0 1.0 |
| Pi3k events in erbb4 signaling 0 2 0.0 1.0 |
| Shc1 events in erbb2 signaling 0 13 0.0 1.0 |
| Erythrocytes take up oxygen and release carbon dioxide 0 1 0.0 1.0 |
| Methionine salvage pathway 1 6 34.93793103448276 0.0342293606409812 |
| Erythrocytes take up carbon dioxide and release oxygen 0 4 0.0 1.0 |
| Cross presentation of soluble exogenous antigens endosomes 2 41 9.08502024291498 0.0233616436749451 |
| Endosomal vacuolar pathway 1 10 19.402298850574716 0.0564062970008856 |
| Cross presentation of particulate exogenous antigens phagosomes 0 3 0.0 1.0 |
| Signaling by erbb4 0 36 0.0 1.0 |
| Shc1 events in erbb4 signaling 0 6 0.0 1.0 |
| Constitutive signaling by ligand responsive egfr cancer variants 0 17 0.0 1.0 |
| Regulation of gene expression by hypoxia inducible factor 0 5 0.0 1.0 |
| Signaling by erbb2 in cancer 0 17 0.0 1.0 |
| Signaling by erbb2 0 37 0.0 1.0 |
| Signaling by fgfr in disease 0 48 0.0 1.0 |
| Ros and rns production in phagocytes 0 16 0.0 1.0 |
| Meiotic synapsis 0 31 0.0 1.0 |
| Fertilization 0 3 0.0 1.0 |
| Signaling by nodal 0 12 0.0 1.0 |
| Prolactin receptor signaling 0 9 0.0 1.0 |
| Cellular response to hypoxia 2 59 6.204986149584488 0.0456361175423009 |
| Antiviral mechanism by ifn stimulated genes 0 73 0.0 1.0 |
| Nuclear signaling by erbb4 0 18 0.0 1.0 |
| Interleukin 7 signaling 0 13 0.0 1.0 |
| Activation of puma and translocation to mitochondria 0 8 0.0 1.0 |
| Elevation of cytosolic ca2 levels 0 6 0.0 1.0 |
| Abc transporters in lipid homeostasis 0 7 0.0 1.0 |
| Bmal1 clock npas2 activates circadian gene expression 0 20 0.0 1.0 |
| Rora activates gene expression 0 17 0.0 1.0 |
| Mitochondrial iron sulfur cluster biogenesis 0 12 0.0 1.0 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0 16 0.0 1.0 |
| Transcription of e2f targets under negative control by dream complex 0 19 0.0 1.0 |
| Downregulation of erbb2 erbb3 signaling 0 10 0.0 1.0 |
| Downregulation of erbb4 signaling 0 7 0.0 1.0 |
| Grb7 events in erbb2 signaling 0 2 0.0 1.0 |
| Sperm motility and taxes 0 1 0.0 1.0 |
| Tandem pore domain potassium channels 0 2 0.0 1.0 |
| Voltage gated potassium channels 0 2 0.0 1.0 |
| Potassium channels 0 15 0.0 1.0 |
| Inwardly rectifying k channels 0 12 0.0 1.0 |
| Spry regulation of fgf signaling 0 14 0.0 1.0 |
| Adaptive immune system 3 504 1.0303678357570574 0.5637795003957968 |
| Cytokine signaling in immune system 3 392 1.342453176643408 0.3971130280707073 |
| Developmental biology 2 665 0.5013892196554736 0.9049794582816209 |
| Acrosome reaction and sperm oocyte membrane binding 0 1 0.0 1.0 |
| Activation of ras in b cells 0 3 0.0 1.0 |
| Downstream signaling events of b cell receptor bcr 2 71 5.119755911517926 0.0634484369785551 |
| Gpvi mediated activation cascade 0 21 0.0 1.0 |
| Smac xiap regulated apoptotic response 0 8 0.0 1.0 |
| Apoptotic cleavage of cellular proteins 0 35 0.0 1.0 |
| Cytochrome c mediated apoptotic response 0 13 0.0 1.0 |
| Activation of caspases through apoptosome mediated cleavage 0 6 0.0 1.0 |
| Formation of apoptosome 0 11 0.0 1.0 |
| Release of apoptotic factors from the mitochondria 0 6 0.0 1.0 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 0 8 0.0 1.0 |
| Activation of noxa and translocation to mitochondria 0 5 0.0 1.0 |
| Activation of bad and translocation to mitochondria 0 16 0.0 1.0 |
| Apoptotic factor mediated response 0 20 0.0 1.0 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 0 28 0.0 1.0 |
| Displacement of dna glycosylase by apex1 0 8 0.0 1.0 |
| Recognition and association of dna glycosylase with site containing an affected purine 0 16 0.0 1.0 |
| Translesion synthesis by polh 0 20 0.0 1.0 |
| Recognition of dna damage by pcna containing replication complex 0 30 0.0 1.0 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0 41 0.0 1.0 |
| Mapk3 erk1 activation 0 8 0.0 1.0 |
| Intrinsic pathway for apoptosis 0 53 0.0 1.0 |
| Hemostasis 2 361 0.955676098323804 0.6234161785061265 |
| Apoptosis 2 159 2.230416806347078 0.2345248549156721 |
| Polb dependent long patch base excision repair 0 9 0.0 1.0 |
| Opioid signalling 0 63 0.0 1.0 |
| Pka mediated phosphorylation of creb 0 13 0.0 1.0 |
| Camk iv mediated phosphorylation of creb 0 8 0.0 1.0 |
| Disinhibition of snare formation 0 4 0.0 1.0 |
| Effects of pip2 hydrolysis 0 17 0.0 1.0 |
| Activation of bh3 only proteins 0 29 0.0 1.0 |
| E2f mediated regulation of dna replication 0 23 0.0 1.0 |
| E2f enabled inhibition of pre replication complex formation 0 10 0.0 1.0 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 0 13 0.0 1.0 |
| Formation of the early elongation complex 0 33 0.0 1.0 |
| Sos mediated signalling 0 7 0.0 1.0 |
| Mapk1 erk2 activation 0 7 0.0 1.0 |
| Raf independent mapk1 3 activation 0 15 0.0 1.0 |
| Irs mediated signalling 0 26 0.0 1.0 |
| Formation of rna pol ii elongation complex 0 58 0.0 1.0 |
| Neuronal system 0 177 0.0 1.0 |
| Transmission across chemical synapses 0 139 0.0 1.0 |
| Neurotransmitter receptors and postsynaptic signal transmission 0 105 0.0 1.0 |
| Neurotransmitter clearance 0 3 0.0 1.0 |
| Neurotransmitter release cycle 0 30 0.0 1.0 |
| Presynaptic depolarization and calcium channel opening 0 4 0.0 1.0 |
| Electric transmission across gap junctions 0 2 0.0 1.0 |
| G protein mediated events 0 40 0.0 1.0 |
| Ca dependent events 0 26 0.0 1.0 |
| Apoptosis induced dna fragmentation 0 11 0.0 1.0 |
| Caspase activation via death receptors in the presence of ligand 0 11 0.0 1.0 |
| Extrinsic pathway of fibrin clot formation 0 1 0.0 1.0 |
| Intrinsic pathway of fibrin clot formation 1 7 29.11206896551724 0.0398211631657538 |
| Golgi cisternae pericentriolar stack reorganization 0 14 0.0 1.0 |
| Early phase of hiv life cycle 0 13 0.0 1.0 |
| Integration of provirus 0 9 0.0 1.0 |
| Budding and maturation of hiv virion 0 27 0.0 1.0 |
| Hiv life cycle 0 144 0.0 1.0 |
| Sulfur amino acid metabolism 1 22 8.305418719211822 0.1199764691278295 |
| Degradation of cysteine and homocysteine 0 12 0.0 1.0 |
| Sulfide oxidation to sulfate 0 5 0.0 1.0 |
| Irf3 mediated activation of type 1 ifn 0 3 0.0 1.0 |
| Synthesis of glycosylphosphatidylinositol gpi 0 12 0.0 1.0 |
| Zbp1 dai mediated induction of type i ifns 0 18 0.0 1.0 |
| Removal of aminoterminal propeptides from gamma carboxylated proteins 0 4 0.0 1.0 |
| Recycling of bile acids and salts 0 6 0.0 1.0 |
| Activation of matrix metalloproteinases 0 6 0.0 1.0 |
| Transport of mature mrnas derived from intronless transcripts 0 43 0.0 1.0 |
| Transport of the slbp dependant mature mrna 0 36 0.0 1.0 |
| Mitochondrial biogenesis 2 85 4.250264214753752 0.0866491789587889 |
| Metabolism of nucleotides 0 82 0.0 1.0 |
| Gap junction trafficking and regulation 0 28 0.0 1.0 |
| Telomere maintenance 0 74 0.0 1.0 |
| Gamma carboxylation transport and amino terminal cleavage of proteins 0 5 0.0 1.0 |
| Attachment of gpi anchor to upar 0 7 0.0 1.0 |
| Hiv infection 2 213 1.6506194395942462 0.350199617154011 |
| Host interactions of hiv factors 2 116 3.084949215143121 0.1448793787749411 |
| Collagen biosynthesis and modifying enzymes 0 30 0.0 1.0 |
| The role of nef in hiv 1 replication and disease pathogenesis 0 20 0.0 1.0 |
| Nef and signal transduction 0 4 0.0 1.0 |
| Nef mediated downregulation of mhc class i complex cell surface expression 0 9 0.0 1.0 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0 16 0.0 1.0 |
| 2 ltr circle formation 0 7 0.0 1.0 |
| Pka activation in glucagon signalling 0 12 0.0 1.0 |
| Signaling by egfr in cancer 0 17 0.0 1.0 |
| Cell cycle 3 613 0.8366803278688525 0.6972739253237927 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 0 29 0.0 1.0 |
| Heparan sulfate heparin hs gag metabolism 0 32 0.0 1.0 |
| Keratan sulfate keratin metabolism 0 17 0.0 1.0 |
| Pp2a mediated dephosphorylation of key metabolic factors 0 6 0.0 1.0 |
| Chrebp activates metabolic gene expression 0 8 0.0 1.0 |
| Integration of energy metabolism 0 71 0.0 1.0 |
| Ampk inhibits chrebp transcriptional activation activity 0 7 0.0 1.0 |
| Triglyceride catabolism 0 13 0.0 1.0 |
| Glucagon signaling in metabolic regulation 0 21 0.0 1.0 |
| Pka mediated phosphorylation of key metabolic factors 0 4 0.0 1.0 |
| Post translational modification synthesis of gpi anchored proteins 0 32 0.0 1.0 |
| Glycosaminoglycan metabolism 0 70 0.0 1.0 |
| Signaling by notch 2 152 2.336140350877193 0.2195629304526211 |
| Regulation of cholesterol biosynthesis by srebp srebf 2 55 6.67593512082092 0.0401909726634089 |
| Eukaryotic translation elongation 0 89 0.0 1.0 |
| Fibronectin matrix formation 0 3 0.0 1.0 |
| Acyl chain remodelling of pe 0 8 0.0 1.0 |
| Acyl chain remodelling of ps 0 9 0.0 1.0 |
| Acyl chain remodeling of cl 0 5 0.0 1.0 |
| Acyl chain remodelling of pc 0 9 0.0 1.0 |
| Reversible hydration of carbon dioxide 0 2 0.0 1.0 |
| Collagen formation 0 44 0.0 1.0 |
| Extracellular matrix organization 0 131 0.0 1.0 |
| Degradation of the extracellular matrix 0 56 0.0 1.0 |
| Reproduction 0 57 0.0 1.0 |
| Acyl chain remodeling of dag and tag 0 2 0.0 1.0 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 1 7 29.11206896551724 0.0398211631657538 |
| Defensins 0 1 0.0 1.0 |
| Translocation of slc2a4 glut4 to the plasma membrane 1 66 2.6716180371352785 0.3190412037162214 |
| Collagen degradation 0 21 0.0 1.0 |
| Regulation of signaling by nodal 0 3 0.0 1.0 |
| Regulation of kit signaling 0 12 0.0 1.0 |
| Signaling by scf kit 0 31 0.0 1.0 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0 21 0.0 1.0 |
| Formation of fibrin clot clotting cascade 1 9 21.829741379310345 0.0509094537479748 |
| Common pathway of fibrin clot formation 0 5 0.0 1.0 |
| Alpha defensins 0 1 0.0 1.0 |
| Acyl chain remodelling of pi 0 4 0.0 1.0 |
| Acyl chain remodelling of pg 0 7 0.0 1.0 |
| Hydrolysis of lpc 1 3 87.37068965517241 0.0172611722851324 |
| Elastic fibre formation 0 23 0.0 1.0 |
| Glutathione conjugation 0 21 0.0 1.0 |
| Glucuronidation 0 4 0.0 1.0 |
| Cytosolic sulfonation of small molecules 0 14 0.0 1.0 |
| Methylation 0 12 0.0 1.0 |
| Phase ii conjugation of compounds 0 53 0.0 1.0 |
| G0 and early g1 0 26 0.0 1.0 |
| Signaling by activin 0 9 0.0 1.0 |
| Cell cell communication 0 79 0.0 1.0 |
| Meiosis 0 54 0.0 1.0 |
| Dag and ip3 signaling 0 30 0.0 1.0 |
| Phospholipid metabolism 2 156 2.2745500113921167 0.2281029575891408 |
| Pi metabolism 0 71 0.0 1.0 |
| Inositol phosphate metabolism 0 40 0.0 1.0 |
| Synthesis of pips at the er membrane 0 5 0.0 1.0 |
| Synthesis of pi 0 5 0.0 1.0 |
| Synthesis of pe 0 12 0.0 1.0 |
| Glycerophospholipid biosynthesis 2 86 4.199248120300752 0.0883929394465974 |
| Synthesis of pc 0 22 0.0 1.0 |
| Synthesis of pa 1 25 7.265086206896552 0.135199366235551 |
| Synthesis of pg 0 8 0.0 1.0 |
| Polo like kinase mediated events 0 16 0.0 1.0 |
| Yap1 and wwtr1 taz stimulated gene expression 0 10 0.0 1.0 |
| Enos activation 0 7 0.0 1.0 |
| Nostrin mediated enos trafficking 0 3 0.0 1.0 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0 9 0.0 1.0 |
| Incretin synthesis secretion and inactivation 0 14 0.0 1.0 |
| Free fatty acids regulate insulin secretion 0 8 0.0 1.0 |
| Circadian clock 0 55 0.0 1.0 |
| Regulation of lipid metabolism by pparalpha 2 95 3.789473684210526 0.1045416046457611 |
| Adrenaline noradrenaline inhibits insulin secretion 0 16 0.0 1.0 |
| Acetylcholine regulates insulin secretion 0 8 0.0 1.0 |
| Crmps in sema3a signaling 0 12 0.0 1.0 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0 10 0.0 1.0 |
| Sema4d in semaphorin signaling 0 23 0.0 1.0 |
| Sema3a pak dependent axon repulsion 0 13 0.0 1.0 |
| G protein beta gamma signalling 0 22 0.0 1.0 |
| Muscle contraction 0 83 0.0 1.0 |
| Eph ephrin mediated repulsion of cells 0 43 0.0 1.0 |
| Ephrin signaling 0 17 0.0 1.0 |
| Epha mediated growth cone collapse 0 23 0.0 1.0 |
| Ephb mediated forward signaling 0 40 0.0 1.0 |
| Prostacyclin signalling through prostacyclin receptor 0 12 0.0 1.0 |
| Signal amplification 0 22 0.0 1.0 |
| Rap1 signalling 0 13 0.0 1.0 |
| Trafficking of ampa receptors 0 20 0.0 1.0 |
| G beta gamma signalling through pi3kgamma 0 15 0.0 1.0 |
| Sialic acid metabolism 0 16 0.0 1.0 |
| Ca2 pathway 0 45 0.0 1.0 |
| Netrin mediated repulsion signals 0 5 0.0 1.0 |
| Dcc mediated attractive signaling 0 13 0.0 1.0 |
| G alpha z signalling events 0 28 0.0 1.0 |
| G alpha i signalling events 0 88 0.0 1.0 |
| Adp signalling through p2y purinoceptor 1 0 17 0.0 1.0 |
| G alpha s signalling events 0 37 0.0 1.0 |
| Cgmp effects 0 7 0.0 1.0 |
| Platelet calcium homeostasis 0 13 0.0 1.0 |
| Reduction of cytosolic ca levels 0 7 0.0 1.0 |
| Sumoylation of sumoylation proteins 0 35 0.0 1.0 |
| Platelet homeostasis 0 51 0.0 1.0 |
| P2y receptors 0 1 0.0 1.0 |
| Trafficking of glur2 containing ampa receptors 0 11 0.0 1.0 |
| Other semaphorin interactions 0 7 0.0 1.0 |
| Sema4d induced cell migration and growth cone collapse 0 18 0.0 1.0 |
| Sema4d mediated inhibition of cell attachment and migration 0 8 0.0 1.0 |
| G alpha 12 13 signalling events 0 57 0.0 1.0 |
| G alpha q signalling events 0 66 0.0 1.0 |
| Sumoylation of intracellular receptors 0 18 0.0 1.0 |
| Pcp ce pathway 2 78 4.644967682363804 0.074753849913789 |
| Nucleotide like purinergic receptors 0 1 0.0 1.0 |
| Adp signalling through p2y purinoceptor 12 0 13 0.0 1.0 |
| Nitric oxide stimulates guanylate cyclase 0 11 0.0 1.0 |
| Protein folding 0 79 0.0 1.0 |
| Olfactory signaling pathway 0 2 0.0 1.0 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 0 27 0.0 1.0 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 1 56 3.160501567398119 0.2781025232559181 |
| Transcriptional regulation of white adipocyte differentiation 0 68 0.0 1.0 |
| Atf6 atf6 alpha activates chaperone genes 0 6 0.0 1.0 |
| Unfolded protein response upr 0 75 0.0 1.0 |
| Ire1alpha activates chaperones 0 44 0.0 1.0 |
| Perk regulates gene expression 0 26 0.0 1.0 |
| Atf6 atf6 alpha activates chaperones 0 8 0.0 1.0 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0 12 0.0 1.0 |
| Atf4 activates genes in response to endoplasmic reticulum stress 0 22 0.0 1.0 |
| Recruitment of numa to mitotic centrosomes 0 90 0.0 1.0 |
| Recruitment of mitotic centrosome proteins and complexes 0 82 0.0 1.0 |
| Chemokine receptors bind chemokines 0 3 0.0 1.0 |
| Mitochondrial trna aminoacylation 0 23 0.0 1.0 |
| Trna aminoacylation 0 43 0.0 1.0 |
| Cytosolic trna aminoacylation 0 24 0.0 1.0 |
| Dopamine clearance from the synaptic cleft 0 2 0.0 1.0 |
| Myoclonic epilepsy of lafora 0 5 0.0 1.0 |
| Diseases of glycosylation 0 76 0.0 1.0 |
| Energy dependent regulation of mtor by lkb1 ampk 0 27 0.0 1.0 |
| Abc family proteins mediated transport 2 75 4.837298726267724 0.0698326152305673 |
| Nuclear receptor transcription pathway 0 29 0.0 1.0 |
| Beta catenin independent wnt signaling 2 117 3.057818459191457 0.1468759864960251 |
| Signal regulatory protein family interactions 0 9 0.0 1.0 |
| Peroxisomal lipid metabolism 0 24 0.0 1.0 |
| Diseases associated with o glycosylation of proteins 0 17 0.0 1.0 |
| Striated muscle contraction 0 16 0.0 1.0 |
| Association of tric cct with target proteins during biosynthesis 0 36 0.0 1.0 |
| Folding of actin by cct tric 0 10 0.0 1.0 |
| Beta oxidation of very long chain fatty acids 0 9 0.0 1.0 |
| Post chaperonin tubulin folding pathway 0 18 0.0 1.0 |
| Formation of tubulin folding intermediates by cct tric 0 21 0.0 1.0 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 0 28 0.0 1.0 |
| Pd 1 signaling 0 5 0.0 1.0 |
| Sumoylation of transcription cofactors 0 41 0.0 1.0 |
| Beta oxidation of pristanoyl coa 0 7 0.0 1.0 |
| Glyoxylate metabolism and glycine degradation 0 22 0.0 1.0 |
| Alpha oxidation of phytanate 0 6 0.0 1.0 |
| Ctla4 inhibitory signaling 0 17 0.0 1.0 |
| Cd28 dependent vav1 pathway 0 7 0.0 1.0 |
| Cd28 dependent pi3k akt signaling 0 15 0.0 1.0 |
| Cd28 co stimulation 0 24 0.0 1.0 |
| Receptor type tyrosine protein phosphatases 0 11 0.0 1.0 |
| Costimulation by the cd28 family 0 39 0.0 1.0 |
| Caspase activation via dependence receptors in the absence of ligand 0 7 0.0 1.0 |
| Role of second messengers in netrin 1 signaling 0 3 0.0 1.0 |
| Adherens junctions interactions 0 18 0.0 1.0 |
| Ncam1 interactions 0 15 0.0 1.0 |
| Cell extracellular matrix interactions 0 16 0.0 1.0 |
| Synthesis of substrates in n glycan biosythesis 0 44 0.0 1.0 |
| Synthesis of udp n acetyl glucosamine 0 8 0.0 1.0 |
| Synthesis of gdp mannose 0 5 0.0 1.0 |
| Asparagine n linked glycosylation 1 245 0.6990531373657434 0.7628758689005497 |
| Synthesis of dolichyl phosphate 0 5 0.0 1.0 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0 59 0.0 1.0 |
| Type i hemidesmosome assembly 0 9 0.0 1.0 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 0 25 0.0 1.0 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0 7 0.0 1.0 |
| Aquaporin mediated transport 0 26 0.0 1.0 |
| Signal transduction by l1 0 20 0.0 1.0 |
| Interaction between l1 and ankyrins 0 12 0.0 1.0 |
| Formyl peptide receptors bind formyl peptides and many other ligands 0 3 0.0 1.0 |
| Rsk activation 0 7 0.0 1.0 |
| Ras activation upon ca2 influx through nmda receptor 0 13 0.0 1.0 |
| Activation of nmda receptors and postsynaptic events 0 68 0.0 1.0 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0 21 0.0 1.0 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0 7 0.0 1.0 |
| Creb1 phosphorylation through the activation of adenylate cyclase 0 9 0.0 1.0 |
| Smooth muscle contraction 0 28 0.0 1.0 |
| Interleukin 1 family signaling 2 95 3.789473684210526 0.1045416046457611 |
| Cell junction organization 0 54 0.0 1.0 |
| Nrcam interactions 0 7 0.0 1.0 |
| Transcriptional regulation of pluripotent stem cells 0 16 0.0 1.0 |
| Interleukin 2 family signaling 0 21 0.0 1.0 |
| Signaling by the b cell receptor bcr 2 91 3.961364084368224 0.0972667725560692 |
| Ionotropic activity of kainate receptors 0 3 0.0 1.0 |
| Ksrp khsrp binds and destabilizes mrna 0 17 0.0 1.0 |
| Regulation of mrna stability by proteins that bind au rich elements 2 79 4.584187742082479 0.0764185806768525 |
| Hur elavl1 binds and stabilizes mrna 0 7 0.0 1.0 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 0 17 0.0 1.0 |
| Auf1 hnrnp d0 binds and destabilizes mrna 2 48 7.697177726926011 0.0313211948292666 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 0 17 0.0 1.0 |
| Activation of the ap 1 family of transcription factors 0 8 0.0 1.0 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 0 18 0.0 1.0 |
| Activated tak1 mediates p38 mapk activation 0 20 0.0 1.0 |
| Mapk targets nuclear events mediated by map kinases 0 27 0.0 1.0 |
| Other interleukin signaling 0 12 0.0 1.0 |
| Signaling by interleukins 3 248 2.1629737609329447 0.1728856135411727 |
| Interleukin 1 processing 0 3 0.0 1.0 |
| Interleukin 17 signaling 0 57 0.0 1.0 |
| Interleukin 12 family signaling 1 43 4.144088669950739 0.221248032604325 |
| Neurofascin interactions 0 6 0.0 1.0 |
| Chl1 interactions 0 7 0.0 1.0 |
| Na cl dependent neurotransmitter transporters 0 4 0.0 1.0 |
| Diseases associated with n glycosylation of proteins 0 18 0.0 1.0 |
| Zinc influx into cells by the slc39 gene family 0 7 0.0 1.0 |
| Binding of tcf lef ctnnb1 to target gene promoters 0 7 0.0 1.0 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0 27 0.0 1.0 |
| Sirt1 negatively regulates rrna expression 0 18 0.0 1.0 |
| Small interfering rna sirna biogenesis 0 9 0.0 1.0 |
| Cation coupled chloride cotransporters 0 4 0.0 1.0 |
| Arachidonate production from dag 0 4 0.0 1.0 |
| Sodium proton exchangers 0 4 0.0 1.0 |
| Sodium calcium exchangers 0 3 0.0 1.0 |
| Metal ion slc transporters 0 15 0.0 1.0 |
| Slc mediated transmembrane transport 2 101 3.5576820839978733 0.1157220533027023 |
| Multifunctional anion exchangers 0 3 0.0 1.0 |
| Transport of vitamins nucleosides and related molecules 0 21 0.0 1.0 |
| Bicarbonate transporters 0 4 0.0 1.0 |
| Transport of bile salts and organic acids metal ions and amine compounds 1 32 5.620689655172414 0.1697199333458323 |
| Regulation of insulin secretion 0 48 0.0 1.0 |
| Synthesis secretion and deacylation of ghrelin 0 5 0.0 1.0 |
| Cell cell junction organization 0 31 0.0 1.0 |
| Nectin necl trans heterodimerization 0 5 0.0 1.0 |
| Glucagon type ligand receptors 0 13 0.0 1.0 |
| Tight junction interactions 0 11 0.0 1.0 |
| Lysosphingolipid and lpa receptors 0 3 0.0 1.0 |
| Transport of inorganic cations anions and amino acids oligopeptides 1 44 4.047313552526062 0.2257734306256001 |
| Sodium coupled phosphate cotransporters 0 2 0.0 1.0 |
| Sphingolipid metabolism 1 62 2.847936687394008 0.3029471279604719 |
| Activation of rac1 0 12 0.0 1.0 |
| Unblocking of nmda receptors glutamate binding and activation 0 9 0.0 1.0 |
| Recycling pathway of l1 0 41 0.0 1.0 |
| Zinc efflux and compartmentalization by the slc30 family 0 5 0.0 1.0 |
| Zinc transporters 0 12 0.0 1.0 |
| Fatty acids bound to gpr40 ffar1 regulate insulin secretion 0 6 0.0 1.0 |
| Proton coupled monocarboxylate transport 1 4 58.241379310344826 0.0229495457607021 |
| Golgi associated vesicle biogenesis 1 55 3.219348659003832 0.2738779694784634 |
| Lysosome vesicle biogenesis 0 32 0.0 1.0 |
| Platelet sensitization by ldl 0 15 0.0 1.0 |
| Passive transport by aquaporins 0 1 0.0 1.0 |
| Vasopressin regulates renal water homeostasis via aquaporins 0 25 0.0 1.0 |
| Gp1b ix v activation signalling 0 7 0.0 1.0 |
| Mrna decay by 5 to 3 exoribonuclease 0 15 0.0 1.0 |
| Mrna decay by 3 to 5 exoribonuclease 1 16 11.63448275862069 0.0887361638400985 |
| Deadenylation of mrna 0 26 0.0 1.0 |
| Deadenylation dependent mrna decay 1 57 3.103756157635468 0.2823029129169494 |
| Thromboxane signalling through tp receptor 0 15 0.0 1.0 |
| Role of abl in robo slit signaling 0 9 0.0 1.0 |
| Organic anion transporters 0 3 0.0 1.0 |
| Inactivation of cdc42 and rac1 0 8 0.0 1.0 |
| Regulation of commissural axon pathfinding by slit and robo 0 7 0.0 1.0 |
| Depolymerisation of the nuclear lamina 0 16 0.0 1.0 |
| Negative regulation of tcf dependent signaling by wnt ligand antagonists 0 5 0.0 1.0 |
| Deactivation of the beta catenin transactivating complex 0 36 0.0 1.0 |
| Signaling by robo receptors 2 197 1.7889338731443996 0.3161898145074803 |
| Anchoring fibril formation 0 8 0.0 1.0 |
| Mucopolysaccharidoses 0 9 0.0 1.0 |
| Notch2 intracellular domain regulates transcription 0 7 0.0 1.0 |
| Visual phototransduction 0 40 0.0 1.0 |
| The retinoid cycle in cones daylight vision 0 1 0.0 1.0 |
| Egfr transactivation by gastrin 0 7 0.0 1.0 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 0 29 0.0 1.0 |
| Downregulation of smad2 3 smad4 transcriptional activity 0 23 0.0 1.0 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 0 41 0.0 1.0 |
| Pi3k akt signaling in cancer 0 58 0.0 1.0 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0 14 0.0 1.0 |
| Downregulation of tgf beta receptor signaling 0 22 0.0 1.0 |
| Binding and uptake of ligands by scavenger receptors 1 17 10.90625 0.0940175554244995 |
| Dap12 interactions 0 21 0.0 1.0 |
| Scavenging of heme from plasma 0 2 0.0 1.0 |
| Synthesis of prostaglandins pg and thromboxanes tx 0 8 0.0 1.0 |
| Abacavir metabolism 0 4 0.0 1.0 |
| Abacavir transport and metabolism 0 6 0.0 1.0 |
| Abacavir transmembrane transport 0 2 0.0 1.0 |
| Hyaluronan uptake and degradation 0 8 0.0 1.0 |
| Tgf beta receptor signaling activates smads 0 28 0.0 1.0 |
| Constitutive signaling by aberrant pi3k in cancer 0 32 0.0 1.0 |
| Crosslinking of collagen fibrils 0 10 0.0 1.0 |
| Condensation of prophase chromosomes 0 23 0.0 1.0 |
| Oxidative stress induced senescence 0 69 0.0 1.0 |
| Mitotic metaphase and anaphase 2 225 1.559908740461018 0.3753572268618609 |
| Interaction with cumulus cells and the zona pellucida 0 1 0.0 1.0 |
| The phototransduction cascade 0 12 0.0 1.0 |
| Condensation of prometaphase chromosomes 0 11 0.0 1.0 |
| Resolution of sister chromatid cohesion 0 120 0.0 1.0 |
| Activation of the phototransduction cascade 0 2 0.0 1.0 |
| Cohesin loading onto chromatin 0 10 0.0 1.0 |
| Establishment of sister chromatid cohesion 0 11 0.0 1.0 |
| Separation of sister chromatids 2 179 1.974427594409753 0.2775343196434237 |
| Mastl facilitates mitotic progression 0 10 0.0 1.0 |
| Fc epsilon receptor fceri signaling 2 108 3.3204237007613373 0.1291322872533562 |
| The canonical retinoid cycle in rods twilight vision 0 4 0.0 1.0 |
| Retinoid cycle disease events 0 2 0.0 1.0 |
| Shc related events triggered by igf1r 0 7 0.0 1.0 |
| Activation of gene expression by srebf srebp 2 42 8.85701754385965 0.0244397265728371 |
| Dap12 signaling 0 19 0.0 1.0 |
| Selenoamino acid metabolism 0 107 0.0 1.0 |
| Metabolism of ingested semet sec mesec into h2se 0 4 0.0 1.0 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 0 29 0.0 1.0 |
| Phosphate bond hydrolysis by nudt proteins 0 6 0.0 1.0 |
| Integrin cell surface interactions 0 37 0.0 1.0 |
| Senescence associated secretory phenotype sasp 0 54 0.0 1.0 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 0 8 0.0 1.0 |
| Hyaluronan biosynthesis and export 0 1 0.0 1.0 |
| Biological oxidations 2 94 3.8310450038138826 0.102708920050235 |
| Gene silencing by rna 0 75 0.0 1.0 |
| Tie2 signaling 0 12 0.0 1.0 |
| Basigin interactions 1 16 11.63448275862069 0.0887361638400985 |
| Pecam1 interactions 0 9 0.0 1.0 |
| Regulation of gene expression in early pancreatic precursor cells 0 3 0.0 1.0 |
| Regulation of gene expression in beta cells 0 12 0.0 1.0 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0 10 0.0 1.0 |
| Glutamate neurotransmitter release cycle 0 17 0.0 1.0 |
| Cytochrome p450 arranged by substrate type 0 15 0.0 1.0 |
| Metabolism of amine derived hormones 0 1 0.0 1.0 |
| P75ntr recruits signalling complexes 0 11 0.0 1.0 |
| Nrif signals cell death from the nucleus 0 14 0.0 1.0 |
| Nade modulates death signalling 0 5 0.0 1.0 |
| Cell death signalling via nrage nrif and nade 0 63 0.0 1.0 |
| Linoleic acid la metabolism 0 7 0.0 1.0 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 0 12 0.0 1.0 |
| Regulation of pyruvate dehydrogenase pdh complex 0 16 0.0 1.0 |
| Copii mediated vesicle transport 0 55 0.0 1.0 |
| Microrna mirna biogenesis 0 24 0.0 1.0 |
| Nf kb is activated and signals survival 0 11 0.0 1.0 |
| Phase i functionalization of compounds 2 39 9.577999051683262 0.0212668157178533 |
| Miscellaneous substrates 0 2 0.0 1.0 |
| Endogenous sterols 0 12 0.0 1.0 |
| Hyaluronan metabolism 0 9 0.0 1.0 |
| Synthesis of 16 20 hydroxyeicosatetraenoic acids hete 0 1 0.0 1.0 |
| Ubiquinol biosynthesis 0 7 0.0 1.0 |
| Synthesis of 15 eicosatetraenoic acid derivatives 0 3 0.0 1.0 |
| Arachidonic acid metabolism 1 18 10.26369168356998 0.0992688536094271 |
| Synthesis of 12 eicosatetraenoic acid derivatives 0 2 0.0 1.0 |
| Synthesis of lipoxins lx 0 1 0.0 1.0 |
| Synthesis of leukotrienes lt and eoxins ex 0 4 0.0 1.0 |
| Synthesis of 5 eicosatetraenoic acids 1 3 87.37068965517241 0.0172611722851324 |
| Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet 0 1 0.0 1.0 |
| Mhc class ii antigen presentation 0 100 0.0 1.0 |
| Molecules associated with elastic fibres 0 18 0.0 1.0 |
| Egfr interacts with phospholipase c gamma 0 2 0.0 1.0 |
| Dopamine neurotransmitter release cycle 0 18 0.0 1.0 |
| Prc2 methylates histones and dna 0 23 0.0 1.0 |
| Activated notch1 transmits signal to the nucleus 0 21 0.0 1.0 |
| Notch1 intracellular domain regulates transcription 0 39 0.0 1.0 |
| Epigenetic regulation of gene expression 0 102 0.0 1.0 |
| Cyp2e1 reactions 0 1 0.0 1.0 |
| Xenobiotics 0 4 0.0 1.0 |
| Eicosanoids 0 1 0.0 1.0 |
| Transcriptional activation of mitochondrial biogenesis 1 51 3.4782758620689656 0.2567353698168294 |
| Mitotic g1 phase and g1 s transition 3 143 3.825382653061225 0.0497022196152891 |
| Cellular senescence 0 131 0.0 1.0 |
| Oncogene induced senescence 0 30 0.0 1.0 |
| Notch hlh transcription pathway 0 21 0.0 1.0 |
| Hsf1 dependent transactivation 0 30 0.0 1.0 |
| Attenuation phase 0 22 0.0 1.0 |
| Cellular response to heat stress 0 93 0.0 1.0 |
| Hsf1 activation 0 25 0.0 1.0 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0 47 0.0 1.0 |
| Regulation of hsf1 mediated heat shock response 0 76 0.0 1.0 |
| Regulation by c flip 0 10 0.0 1.0 |
| Defects in biotin btn metabolism 0 8 0.0 1.0 |
| Metabolism of polyamines 2 48 7.697177726926011 0.0313211948292666 |
| Glycogen synthesis 0 11 0.0 1.0 |
| Loss of function of smad2 3 in cancer 0 7 0.0 1.0 |
| Nuclear pore complex npc disassembly 0 36 0.0 1.0 |
| Detoxification of reactive oxygen species 0 24 0.0 1.0 |
| Defects in vitamin and cofactor metabolism 0 18 0.0 1.0 |
| Defects in cobalamin b12 metabolism 0 10 0.0 1.0 |
| Trp channels 0 7 0.0 1.0 |
| Irf3 mediated induction of type i ifn 0 8 0.0 1.0 |
| Chromatin modifying enzymes 1 210 0.8190067645603036 0.7081203622526762 |
| Wnt ligand biogenesis and trafficking 0 9 0.0 1.0 |
| Signaling by tgf beta receptor complex in cancer 0 8 0.0 1.0 |
| Apoptotic cleavage of cell adhesion proteins 0 9 0.0 1.0 |
| Amino acid transport across the plasma membrane 0 17 0.0 1.0 |
| Integrin signaling 0 18 0.0 1.0 |
| Dscam interactions 0 9 0.0 1.0 |
| Peptide ligand binding receptors 1 17 10.90625 0.0940175554244995 |
| Ncam signaling for neurite out growth 0 34 0.0 1.0 |
| L1cam interactions 0 91 0.0 1.0 |
| Semaphorin interactions 0 48 0.0 1.0 |
| Nephrin family interactions 0 17 0.0 1.0 |
| Netrin 1 signaling 0 33 0.0 1.0 |
| Class b 2 secretin family receptors 0 25 0.0 1.0 |
| Class a 1 rhodopsin like receptors 1 21 8.721551724137932 0.1148438684626223 |
| Signaling by gpcr 1 204 0.8437234584678104 0.6975597336091772 |
| P130cas linkage to mapk signaling for integrins 0 9 0.0 1.0 |
| Transcriptional regulation by tp53 0 333 0.0 1.0 |
| Defective b4galt1 causes b4galt1 cdg cdg 2d 0 1 0.0 1.0 |
| Defective ext2 causes exostoses 2 0 11 0.0 1.0 |
| Defective chst6 causes mcdc1 0 1 0.0 1.0 |
| Defective chsy1 causes tpbs 0 4 0.0 1.0 |
| Defective chst14 causes eds musculocontractural type 0 4 0.0 1.0 |
| Defective chst3 causes sedcjd 0 4 0.0 1.0 |
| Defective b4galt7 causes eds progeroid type 0 13 0.0 1.0 |
| Diseases associated with glycosaminoglycan metabolism 0 26 0.0 1.0 |
| Grb2 sos provides linkage to mapk signaling for integrins 0 9 0.0 1.0 |
| Sumoylation of ubiquitinylation proteins 0 39 0.0 1.0 |
| Formation of senescence associated heterochromatin foci sahf 0 15 0.0 1.0 |
| Sumoylation of transcription factors 0 18 0.0 1.0 |
| Processing and activation of sumo 0 10 0.0 1.0 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 0 8 0.0 1.0 |
| Pou5f1 oct4 sox2 nanog repress genes related to differentiation 0 6 0.0 1.0 |
| Fceri mediated nf kb activation 2 68 5.354066985645933 0.0588003571543418 |
| Fceri mediated ca 2 mobilization 0 20 0.0 1.0 |
| Fceri mediated mapk activation 0 24 0.0 1.0 |
| Role of lat2 ntal lab on calcium mobilization 0 12 0.0 1.0 |
| Signaling by notch1 hd domain mutants in cancer 0 9 0.0 1.0 |
| Eph ephrin signaling 0 80 0.0 1.0 |
| Stimuli sensing channels 0 38 0.0 1.0 |
| Notch2 activation and transmission of signal to the nucleus 0 16 0.0 1.0 |
| Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant 0 4 0.0 1.0 |
| Caspase mediated cleavage of cytoskeletal proteins 0 12 0.0 1.0 |
| Acetylcholine neurotransmitter release cycle 0 11 0.0 1.0 |
| Fbxw7 mutants and notch1 in cancer 0 5 0.0 1.0 |
| Signaling by notch1 pest domain mutants in cancer 0 45 0.0 1.0 |
| Signaling by leptin 0 8 0.0 1.0 |
| Regulation of plk1 activity at g2 m transition 0 87 0.0 1.0 |
| Cytosolic iron sulfur cluster assembly 0 13 0.0 1.0 |
| Trif mediated programmed cell death 0 4 0.0 1.0 |
| Dna damage telomere stress induced senescence 0 38 0.0 1.0 |
| Insulin processing 0 21 0.0 1.0 |
| Peptide hormone metabolism 0 43 0.0 1.0 |
| Nuclear envelope breakdown 0 54 0.0 1.0 |
| Activation of nima kinases nek9 nek6 nek7 0 7 0.0 1.0 |
| Rmts methylate histone arginines 0 36 0.0 1.0 |
| Hats acetylate histones 0 90 0.0 1.0 |
| Hdms demethylate histones 0 25 0.0 1.0 |
| Pkmts methylate histone lysines 1 46 3.8666666666666663 0.2347468088648468 |
| Hdacs deacetylate histones 0 40 0.0 1.0 |
| Regulation of innate immune responses to cytosolic dna 0 11 0.0 1.0 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0 5 0.0 1.0 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 0 7 0.0 1.0 |
| Sumoylation of dna damage response and repair proteins 0 76 0.0 1.0 |
| Sumo is proteolytically processed 0 6 0.0 1.0 |
| Sumo is transferred from e1 to e2 ube2i ubc9 0 7 0.0 1.0 |
| Sumo is conjugated to e1 uba2 sae1 0 5 0.0 1.0 |
| Scavenging by class f receptors 0 5 0.0 1.0 |
| Scavenging by class a receptors 0 10 0.0 1.0 |
| Ecm proteoglycans 0 37 0.0 1.0 |
| Non integrin membrane ecm interactions 0 37 0.0 1.0 |
| Syndecan interactions 0 20 0.0 1.0 |
| Laminin interactions 0 23 0.0 1.0 |
| Nuclear envelope ne reassembly 0 71 0.0 1.0 |
| Initiation of nuclear envelope ne reformation 0 20 0.0 1.0 |
| Sumoylation 0 155 0.0 1.0 |
| Glycogen storage diseases 0 10 0.0 1.0 |
| Ion channel transport 0 82 0.0 1.0 |
|
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