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b8dc22f verified
Term es nes pval sidak fdr geneset_size leading_edge
Selenoamino acid metabolism -0.5832523645771811 -4.12849310763709 3.651483830835467e-05 0.050495967325216135 0.03571173373985852 87 P83731,P62424,P30050,P42766,O43324,P62280,P32969,P62277,P62910,P62906,P46779,P27635,P00390,P07814,Q16881,Q07020,P62269,P23526,P15880,P26373,P41252,P05388,P18621,Q02878,P63220,P83881,P62249,P18124,P14868,Q02543,P62857,P49591,P49207,P62917,P08708,P50914,P60866,P61247,P46781,P40429,P46782,P62753,P84098,P62701,P61313,P46777,P54136,P62241,Q15046,P36578,O43252,P47914,P47897,P08865,P46776,P61927
Protein localization 0.6502505618049765 4.054072234262439 5.033366277640283e-05 0.0689341418377876 0.03571173373985852 74 P21796,P51648,Q15388,Q9Y5J9,Q9NS69,Q9NX63,Q13505,Q9Y3D6,Q99595,O75874,P06576,O00116,O60830,Q2T9J0,P09601,O94826,Q6QHF9,Q9NR77,Q5JRX3,O43615,Q8N4H5,P50402,P46379,Q9BY49,Q10713,Q15067,O14925,O75431
Nonsense mediated decay nmd -0.537832332975987 -3.728049552028868 0.0001929674420542149 0.23955175455389877 0.06832696405772487 89 P83731,P62424,P30050,P42766,P62280,P32969,P62277,P62910,P62906,P46779,P27635,Q07020,P15170,P62269,P15880,P26373,P05388,P18621,Q02878,P63220,P83881,P62249,P18124,Q02543,P62857,P49207,P62917,P08708,Q15287,Q9NPI6,P50914,P60866,P61247,P46781,P40429,P46782,Q8ND04,P62753,P84098,P62701,P61313,P46777,P62241,Q9HAU5,P36578,P47914,P08865,P46776,P61927
Eukaryotic translation elongation -0.5746933554953464 -3.714651429110389 0.00020348398887115593 0.25081787056674837 0.06832696405772487 76 P83731,P62424,P42766,P30050,P62280,P32969,P62277,P62910,P62906,P46779,P27635,P26641,Q07020,P62269,P15880,P26373,P05388,P18621,Q02878,Q05639,P63220,P83881,P62249,P18124,Q02543,P62857,P49207,P62917,P08708,P50914,P60866,P46781,P61247,P40429,P46782,P62753,P84098,P62701,P61313,P46777,P62241,P36578,P47914,P08865,P13639,P46776,P61927
Response of eif2ak4 gcn2 to amino acid deficiency -0.5694443158736132 -3.6684462729181124 0.00024402896046948896 0.29271342277200363 0.06832696405772487 76 P83731,P62424,P42766,P30050,P62280,P32969,P62277,P62910,P62906,P46779,P27635,Q07020,P62269,P15880,P26373,P05388,P18621,Q02878,P63220,P83881,P62249,P18124,Q02543,P62857,P49207,P62917,Q92616,P08708,P50914,P60866,P41091,P46781,P61247,P40429,P46782,P62753,P84098,P62701,P61313,P46777,P62241,P36578,P47914,P08865,P46776,P61927
Cellular response to starvation -0.5298326746272108 -3.6250469691596847 0.0002889089389332966 0.33636369736716987 0.06832696405772487 87 P83731,P62424,P30050,P42766,P62280,P32969,P62277,P62910,P62906,P46779,P27635,Q07020,P62269,P15880,P26373,P05388,P18621,Q02878,P63220,P83881,P62249,P18124,Q02543,P62857,P49207,P62917,Q92616,P08708,P50914,P60866,P41091,P61247,P46781,P40429,P46782,P62753,P84098,P62701,P61313,P46777,P62241,P36578,P21283,P47914,P08865,P46776,P61927
Mitochondrial protein import 0.7296386223735165 3.4958894736525417 0.000472484364723913 0.48860538867188946 0.09577933050617628 33 Q99595,P21796,P06576,Q10713,Q15388,O94826,Q9Y5J9,Q5JRX3,O14925,Q9NS69,Q8N4H5,Q9NX63,O43615,Q13505,P08574,O60830,O75431
Eukaryotic translation initiation -0.4905638440772494 -3.188919675518635 0.0014280555262649042 0.8683829993714669 0.16427277745932103 100 P83731,P62424,P30050,P42766,P49770,P62280,P32969,P62277,P62910,Q13144,P62906,P46779,P27635,Q07020,P62269,O15371,P15880,P26373,P05388,P18621,Q14240,Q02878,P63220,P83881,P62249,P18124,Q02543,P62857,P49207,P60842,P62917,P50914,P60866,P41091,P61247,P40429,P46782,Q9UBQ5,Q14232,P62753,P84098,P62701,P61313,P46777,P62241,Q13347,P36578,P56537,P47914,P08865,P46776,P61927
Metabolism of nucleotides -0.5542853561497003 -3.0864206740974307 0.002025819920392191 0.9437277722194742 0.16427277745932103 51 P22102,P32321,Q01433,P00390,Q16881,P27708,P00492,Q9NRF8,P33316,P23921,Q9BY32,P04183,P30520,P00568,P15531,P12268,P22234,P31939,P49915,Q13232,P36639,P35754,P22392,P11172
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5669499128439417 3.056901092514746 0.002236380561831286 0.9582884749613861 0.16427277745932103 62 P13073,P03886,P56385,O75947,O43676,P09669,P06576,P20674,O75964,Q16718,Q9P0J0,Q9NPL8,Q9H845,P00403,P08574,Q86Y39,O95168,O75306,O14949,P21912,Q9Y6M9,Q9UDW1
Organelle biogenesis and maintenance 0.5058123253822018 2.9794562529617443 0.002887604595501969 0.9834842090774906 0.16427277745932103 100 P41208,O43924,Q6UXV4,Q9BUR5,Q9NX63,Q13505,P56385,O75947,Q15051,O43805,P06576,Q92845,A6NIH7,O75964,P04350,P48735,O95684,O00411,O94927,Q04837,P61163,P68371,Q5XKP0,Q9BUF5,P07437,Q13561,P78371,Q13885,P00367,Q9Y512,O75935,Q9BVA1,P36542,A0AVF1,Q10713,O75431,Q9Y496
Digestion 0.9956471271038886 2.9668344137094906 0.0030088295521266684 0.9861013725791621 0.16427277745932103 1
Digestion and absorption 0.9956471271038886 2.9668344137094906 0.0030088295521266684 0.9861013725791621 0.16427277745932103 1
Scavenging by class b receptors 0.9953569355774812 2.9653786622775127 0.0030231057381056026 0.9863809316045579 0.16427277745932103 1
Hydrolysis of lpc 0.9941961694718514 2.9595538125979117 0.0030808489043288034 0.9874554976650769 0.16427277745932103 1
Synthesis of 5 eicosatetraenoic acids 0.9930354033662218 2.953726012923827 0.0031396261387213187 0.9884623293036651 0.16427277745932103 1
Choline catabolism -0.9985490423679259 -2.943566519346424 0.003244540898835524 0.9900629856363837 0.16427277745932103 1 P49419
Chylomicron clearance -0.9959373186302591 -2.9303319647212174 0.0033860006647019603 0.9918756355057786 0.16427277745932103 1 P01130
Metal ion slc transporters 0.9822983168891468 2.8996791172911514 0.0037354485081382283 0.995060673130481 0.16427277745932103 1
Zinc transporters 0.9822983168891468 2.8996791172911514 0.0037354485081382283 0.995060673130481 0.16427277745932103 1
Zinc efflux and compartmentalization by the slc30 family 0.9822983168891468 2.8996791172911514 0.0037354485081382283 0.995060673130481 0.16427277745932103 1
Glucagon type ligand receptors -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Prostacyclin signalling through prostacyclin receptor -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
G protein activation -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Potassium channels -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Olfactory signaling pathway -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Inwardly rectifying k channels -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Activation of the phototransduction cascade -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Presynaptic function of kainate receptors -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Sensory perception of taste -0.9898432965757035 -2.8993886209975765 0.003738911563187397 0.9950849764163128 0.16427277745932103 1 P62873
Sphingolipid metabolism 0.6818132873068962 2.8984161370357473 0.0037505259552161885 0.9951656156850899 0.16427277745932103 26 O95470,P51648,P10619,Q06136,Q96G23,P04062,P27544,Q16880
Sphingolipid de novo biosynthesis 0.880982750968765 2.8814581072503236 0.003958398512041494 0.9964046502732341 0.16427277745932103 10 P51648,O95470,P27544,Q06136
The citric acid tca cycle and respiratory electron transport 0.49178682365898463 2.867177929636769 0.004141500990085367 0.9972302354845627 0.16427277745932103 95 P13073,P21796,P03886,P56385,O75947,O43676,P09669,P06576,P20674,O75964,P53985,Q16718,P48735,Q9P0J0,Q9NPL8,Q15120,Q9H845,Q13423,P00403,P35613,P08574,Q86Y39,O95168,O75306,O14949,P21912,Q9Y6M9,Q9UDW1
Biotin transport and metabolism -0.9131526725435396 -2.8472689041039376 0.004409609712541673 0.9981098004208037 0.16427277745932103 8 P05165,P11498,Q96RQ3,O00763,Q13085,P50747
Regulation of gene expression by hypoxia inducible factor 0.9712710388856645 2.8439094119692894 0.004456371588184016 0.9982316766140684 0.16427277745932103 1
Defects in vitamin and cofactor metabolism -0.8483842571562454 -2.831992693364757 0.004625890571118063 0.9986112735833631 0.16427277745932103 10 P05165,P11498,Q96RQ3,Q13085,P50747
Lgi adam interactions -0.9753337202553328 -2.8253601126343866 0.004722750474750015 0.9987903907164258 0.16427277745932103 1 Q15334
Toxicity of botulinum toxin type d botd 0.9674985490423679 2.824769495079793 0.004731464047254441 0.9988053250790013 0.16427277745932103 1
Neurotoxicity of clostridium toxins 0.9674985490423679 2.824769495079793 0.004731464047254441 0.9988053250790013 0.16427277745932103 1
Nucleotide catabolism -0.9073780129772908 -2.8229624906237336 0.004758213814708867 0.9988500307155295 0.16427277745932103 8 Q9BY32,P36639
Acyl chain remodelling of pe 0.9645966337782935 2.810025437666109 0.004953758449154133 0.9991298560383484 0.16427277745932103 1
P75ntr recruits signalling complexes -0.9706906558328142 -2.8015656210410653 0.005085529722467896 0.999278933108812 0.16427277745932103 1 O14920
Netrin mediated repulsion signals -0.969820081253592 -2.7970984642455963 0.005156381624426665 0.9993482405484424 0.16427277745932103 1 Q06124
Abacavir transmembrane transport 0.9616947185142194 2.7952631083816275 0.00518574915854586 0.9993749782731388 0.16427277745932103 1
Keratan sulfate biosynthesis 0.961404526987812 2.793785871538318 0.005209496113931955 0.9993957950730611 0.16427277745932103 1
Tnfr1 mediated ceramide production -0.9669181659895179 -2.782194965288742 0.005399259393748412 0.9995390897308174 0.16655541477671737 1 P63244
Scavenging of heme from plasma 0.955310504933256 2.762721805644919 0.0057321599812845125 0.9997133753374026 0.1712308177708784 1
Purine catabolism -0.9156123002196153 -2.7487298102707345 0.005982667956604182 0.999799541280532 0.1712308177708784 7 Q9BY32,P36639
Acyl chain remodelling of ps -0.9585026117237029 -2.7388619448948526 0.0061652256152378015 0.9998455336996184 0.1712308177708784 1 Q9BZF1
Gamma carboxylation transport and amino terminal cleavage of proteins 0.9495066744051075 2.7330624575528986 0.00627484321640992 0.9998679137642819 0.1712308177708784 1
Defects of contact activation system cas and kallikrein kinin system kks 0.9495066744051075 2.7330624575528986 0.00627484321640992 0.9998679137642819 0.1712308177708784 1
Defective factor ix causes hemophilia b 0.9495066744051075 2.7330624575528986 0.00627484321640992 0.9998679137642819 0.1712308177708784 1
Cholesterol biosynthesis 0.7201948260636742 2.721799254585016 0.00649275699227525 0.9999032385489521 0.17383438060450154 18 Q9UBM7,O76062,P37268,P48449,Q15392,Q15800,Q16850
Rnd1 gtpase cycle 0.7511580525715404 2.70292773686764 0.006873168724643053 0.9999438058496917 0.17752225748004186 15 P38159,P02786,P51648,O75976,Q15058,O43396
Sulfide oxidation to sulfate 0.9431224608241441 2.700353550928722 0.0069265824597688486 0.9999479350503464 0.17752225748004186 1
Rnd2 gtpase cycle 0.7274623648084386 2.696567893848552 0.007005811429797282 0.9999535081333113 0.17752225748004186 17 P38159,P02786,P51648,O43396,Q15058,Q07065
Defects in biotin btn metabolism -0.8960130622787794 -2.6670267838365467 0.007652557294642648 0.9999815554472891 0.17982023230353067 7 P05165,P11498,Q96RQ3,Q13085,P50747
Terminal pathway of complement 0.9361578641903658 2.664571700674391 0.00770864313020958 0.9999829769674623 0.17982023230353067 1
Transport of nucleotide sugars 0.9358676726639584 2.663078548253867 0.0077429337537013865 0.9999837915933589 0.17982023230353067 1
Cristae formation 0.6979530030408533 2.6626719218319304 0.007752295682264432 0.9999840071502449 0.17982023230353067 19 P36542,Q5XKP0,P06576,Q6UXV4,O75964,Q9BUR5,Q9NX63,Q9Y512,P56385,Q13505,O75947,O75431
Respiratory electron transport 0.5359726883774271 2.6602297376832302 0.007808736801668603 0.9999852473348283 0.17982023230353067 53 P13073,Q86Y39,P20674,O95168,O75306,O14949,P03886,Q9H845,Q16718,P21912,Q9P0J0,P00403,P08574,Q9Y6M9,Q9UDW1,O43676,P09669
Mitochondrial calcium ion transport 0.7318514019796319 2.6581608303179243 0.007856838902620789 0.9999862281312898 0.17982023230353067 16 P21796,Q10713,P45880,Q8NE86,Q9BPX6,Q9H300,Q8WWC4,Q9UJZ1,Q99623,O95202
Passive transport by aquaporins 0.9326755658734766 2.6466420737846383 0.008129534806546879 0.9999906763461813 0.18310809349984164 1
Metabolism of ingested semet sec mesec into h2se -0.9390597794544062 -2.6381066947523784 0.00833703466474267 0.9999930713295516 0.183439857704588 1 P23526
Diseases of metabolism -0.5049745919320646 -2.6354406315794483 0.008402812368427215 0.9999936937478375 0.183439857704588 45 Q14376,P23526,P05165,P11498,Q96RQ3,P48507,P37837,Q13085,P22570,Q7Z4W1,P51570,P07686,P48506,Q04446,P50747,P34949
G alpha q signalling events -0.7060068515791901 -2.5988440073081196 0.009353826907151586 0.9999983839849276 0.1910090353404148 15 P62873,Q9BV23
Slc mediated transmembrane transport 0.6869278567840275 2.597919064218387 0.009379059783485966 0.9999984413511956 0.1910090353404148 19 Q70HW3,Q9UBX3,P30825,P53985,Q8NEW0
Elastic fibre formation -0.9294834590829616 -2.588153148999835 0.009649206939060573 0.999998941557689 0.1910090353404148 1 P05556
Fibronectin matrix formation -0.9294834590829616 -2.588153148999835 0.009649206939060573 0.999998941557689 0.1910090353404148 1 P05556
Molecules associated with elastic fibres -0.9294834590829616 -2.588153148999835 0.009649206939060573 0.999998941557689 0.1910090353404148 1 P05556
Met interacts with tns proteins -0.9294834590829616 -2.588153148999835 0.009649206939060573 0.999998941557689 0.1910090353404148 1 P05556
Linoleic acid la metabolism -0.9291932675565542 -2.586636040362228 0.009691790376680665 0.9999990042087614 0.1910090353404148 1 P33121
Mitophagy 0.7812090213950884 2.5683568835874295 0.010218189609782158 0.9999995317200259 0.1982494180019126 11 P21796,Q8IWA4,Q15388,O94826,Q9NS69,Q8N4H5
Androgen biosynthesis 0.9167150319210682 2.5641375783452713 0.01034325367456912 0.9999996085894478 0.1982494180019126 1
Srp dependent cotranslational protein targeting to membrane -0.421969280296824 -2.559632211570363 0.01047829904872688 0.9999996774972608 0.1982494180019126 91 P83731,P62424,P61011,P30050,P42766,P62280,P32969,P62277,P62910,P60468,P62906,P46779,P27635,Q07020,P62269,P15880,P26373,P05388,P18621,Q02878,P63220,P83881,P62249,P18124,Q02543,P62857,P49207,P62917,P08708,P09132,P50914,P60866,P61247,P46781,P40429,P46782,P62753,P84098,P62701,P61313,P46777,P62241,P36578,P47914,O76094,P08865,P46776,P61927
Iron uptake and transport 0.6894788224512569 2.545410548916052 0.010914932495279084 0.9999998275978789 0.20379327908948713 18 P02786,P09601,Q9Y487,P30519
Estrogen stimulated signaling through prkcz -0.9201973302379244 -2.539507827107777 0.011100856137821857 0.9999998679649361 0.2045729202541457 1 P28482
Glycerophospholipid biosynthesis 0.6090910353696128 2.53091860926775 0.011376424367551818 0.9999999110929368 0.20696341253276965 28 P40939,Q9NPH0,Q8N2A8,Q9HCL2,Q96N66,Q8IV08,Q9HBU6,P35790,Q8NCC3,Q9NQZ5,Q9NP80,P43304
Selective autophagy 0.5930001158264129 2.521689521668491 0.011679274207226031 0.9999999424395405 0.20978341898802205 32 P21796,Q8IWA4,Q9BUF5,Q15388,O94826,P04350,Q13885,P08670,Q9NS69,Q8N4H5,Q9BVA1
Regulation of tnfr1 signaling -0.8586934613638959 -2.509337704585537 0.01209577843410714 0.9999999683510151 0.21454886997497544 7 O14920,P63244,Q96BN8
Rrna processing -0.4582322192691312 -2.483049182104299 0.01302631011873534 0.9999999916897921 0.22569124739535426 171 P83731,P62424,P62263,P78316,P46778,P46087,P62906,Q06265,P27635,Q8IY81,Q07020,Q14690,Q9Y5J1,Q9Y2R4,Q9UI30,Q9H6R4,P18124,P78346,Q02543,P49207,P39023,O00566,P60866,Q14692,P62266,Q9NQT4,P61513,P62753,P62701,Q9ULX3,P47914,P25398,P30050,Q8IV48,P56182,Q9NX24,P62269,Q9NPD3,Q15061,Q02878,P63220,P62857,Q9Y2P8,P62917,Q13895,Q13868,P62847,P61353,P40429,P46782,Q9H8H0,P84098,P61313,P55769,Q2NL82,O00541,P36578,P63173,Q12788,Q01780,P62851,P62244,P61247,P61927,P42766,P62280,P32969,P62910,Q9Y2L1,Q5SY16,Q9BVP2,P15880,P05388,P18621,P18077,P83881,P62249,Q9BQ52,O00567,Q99714,P50914,O95059,O75818,Q9NXF1,Q9NXG2,P62241,O60832,O75691,P62888,P62277,P46779,Q9NYH9,Q9H9L3,P26373,P08708,Q13601,P62081,P62750,Q9NV06,Q9Y2X3,P46781,P62899,P62829,Q5RKV6,P46777,Q9BV38,Q9NRX1,Q9NY93,Q14137,Q9Y3B2,P08865,P46776
Hs gag biosynthesis 0.9010446894950672 2.4826187376964373 0.013042059398463035 0.9999999918758488 0.22569124739535426 1
Synthesis of lipoxins lx 0.8978525827045853 2.4659516814241758 0.013664976629584213 0.9999999966833393 0.23362170888409642 1
Acyl chain remodelling of pi 0.8952408589669186 2.452299751760689 0.0141946361337002 0.9999999984523242 0.23751756296666507 1
Metabolism of steroids 0.519035230535302 2.451464549160276 0.014227620050857315 0.999999998524089 0.23751756296666507 46 Q9UBM7,P49327,O75845,O76062,P30536,P37268,P48449,P38435,Q15392,Q15800,P04062,Q16850
Pink1 prkn mediated mitophagy 0.8335622612483968 2.4221127619402276 0.015430561604057758 0.9999999997390412 0.24999829751224478 8 P21796,Q8IWA4,Q15388,O94826,Q9NS69,Q8N4H5
Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0.8891468369123627 2.4203923172090924 0.015503770388356264 0.9999999997651734 0.24999829751224478 1
Runx3 regulates notch signaling 0.8891468369123627 2.4203923172090924 0.015503770388356264 0.9999999997651734 0.24999829751224478 1
Akt phosphorylates targets in the nucleus 0.887986070806733 2.4143063685639463 0.015765200004195457 0.9999999998389062 0.2513575146736332 1
Mitochondrial biogenesis 0.5652474168122762 2.4078189292902445 0.016048138262775513 0.9999999998928738 0.2530256466097606 35 P36542,Q5XKP0,P06576,Q6UXV4,O75964,P48735,P00367,Q9BUR5,O00411,Q9NX63,Q9Y512,P56385,Q13505,O75947,Q04837,O75431
Nuclear envelope ne reassembly 0.5077404937910152 2.3796840380956183 0.017327488146582137 0.9999999999830917 0.2701945679120885 50 Q92621,P42167,Q9BUF5,Q13885,P04350,Q86Y07,Q8N1F7,Q8NFH5,P57740,P50402,Q9BVA1,Q8NFH4,Q86XL3,Q9BTX1,Q96FZ7
Lysine catabolism -0.8265981518415361 -2.37150480752769 0.017715816216187896 0.9999999999903502 0.2732472088127242 7 P49419
Maturation of protein 3a 0.8757980266976211 2.350245206088459 0.018761047310227763 0.9999999999978698 0.28406826540065155 1
Regulation of foxo transcriptional activity by acetylation -0.8842135809634052 -2.3491213875374966 0.018817770928584387 0.9999999999980376 0.28406826540065155 1 Q96EB6
Surfactant metabolism 0.871735345327917 2.3288280579960885 0.019868176366182322 0.9999999999995708 0.29676781330118646 1
Assembly of active lpl and lipc lipase complexes 0.8702843876958797 2.3211715187349538 0.020277588687011905 0.9999999999997627 0.2997281077798947 1
Biosynthesis of epa derived spms 0.8670922809053979 2.304313255488826 0.021205065397642775 0.9999999999999382 0.310206059786135 1
Sealing of the nuclear envelope ne by escrt iii 0.7260067262047174 2.2900704989274066 0.0220172302037287 0.9999999999999809 0.3188005067254186 11 Q9BUF5,Q13885,P04350,Q9BVA1,Q96FZ7
Cytosolic trna aminoacylation -0.5772423569162489 -2.2802423298808217 0.022593320062949562 0.9999999999999918 0.3238375875689437 23 O43324,P54136,Q15181,P23381,P56192,P41252,Q15046,P26639,P47897,P07814,P14868,O43776,P26640,Q9NSD9,P49591,P54577,P49588
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.707833477706783 2.258044760639471 0.023942868978006127 0.9999999999999989 0.33974931079790693 12 P09601,P46379
Tgf beta receptor signaling activates smads -0.7503991350882236 -2.2394463067965753 0.02512689122766787 0.9999999999999998 0.35302038269367036 9 P22681,Q9Y3F4,P62136,P61081,Q9UNE7,P62140,Q9Y5K5
Ire1alpha activates chaperones 0.5885496302056049 2.2323300670923345 0.025593156080772284 0.9999999999999999 0.35431376930037095 25 O76024,P43307,Q9NWM8,P49748,O43731
Transferrin endocytosis and recycling 0.7141393457330154 2.228994377097149 0.02581427891279997 0.9999999999999999 0.35431376930037095 11 P02786,Q9Y487
Nectin necl trans heterodimerization 0.852002321532211 2.2243670535268536 0.02612375864119243 1.0 0.35431376930037095 1
Class i peroxisomal membrane protein import 0.7686500559252878 2.2129163615929617 0.026903412461351195 1.0 0.35431376930037095 9 P51648,Q9NR77
Pi3k akt activation -0.8586767266395529 -2.2122393547959454 0.026950130933945715 1.0 0.35431376930037095 1 P61586
Rho gtpases activate rhotekin and rhophilins -0.8586767266395529 -2.2122393547959454 0.026950130933945715 1.0 0.35431376930037095 1 P61586
Triglyceride biosynthesis 0.8488102147417291 2.2074033383395744 0.02728589336324516 1.0 0.35431376930037095 1
Vitamin b1 thiamin metabolism 0.8476494486360994 2.2012303299782277 0.027719722168656924 1.0 0.35431376930037095 1
Ptk6 regulates rtks and their effectors akt1 and dok1 -0.8560650029018861 -2.1981602016747774 0.027937691671121367 1.0 0.35431376930037095 1 P22681
Flt3 signaling by cbl mutants -0.8560650029018861 -2.1981602016747774 0.027937691671121367 1.0 0.35431376930037095 1 P22681
Platelet activation signaling and aggregation -0.43699446746791515 -2.1977690391905234 0.027965568824271703 1.0 0.35431376930037095 59 Q9UNF1,P28482,P21333,P37802,Q06124,P62873,Q9BV23,P23528,O75083,P04075
Cilium assembly 0.4708769794353216 2.1933752310811085 0.028280355377779065 1.0 0.3551311883280398 65 P41208,O43924,Q9BUF5,Q92845,P07437,P78371,A6NIH7,Q10713,Q13885,P04350,O95684,O75935,O94927,Q9BVA1
Synthesis of active ubiquitin roles of e1 and e2 enzymes -0.7095872420474194 -2.185195129350529 0.028874542498784628 1.0 0.35870829030264045 10 P60604,P68036,A0AVT1,Q93008,Q96BN8,P22314
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.6283244760167017 2.1825252247480815 0.029070791673575513 1.0 0.35870829030264045 18 O43493,P07942,O43852,Q13217,O76024,Q07065,Q9BTY2,Q02818
Regulation of signaling by cbl -0.8311080725685985 -2.175467306551207 0.029595115497415003 1.0 0.36103385518428327 6 P46109,P22681,P07947
Rhog gtpase cycle 0.513174777608846 2.1703036983939152 0.029983846637338107 1.0 0.36103385518428327 40 P02786,P42167,P61604,O15173,O96013,Q8TAA9,Q16718,Q86Y07,P50402,Q13190,Q14739,O95202,Q86XL3
Phase i functionalization of compounds 0.65468086385037 2.169792780932922 0.03002254750651545 1.0 0.36103385518428327 15 Q16850,O43169,Q6QHF9,P07099
Metabolism of folate and pterines 0.7584927542601612 2.1646775697201455 0.030412385984987633 1.0 0.36133004325624857 9 Q9H2D1,P00374
Effects of pip2 hydrolysis -0.8886343851756056 -2.162801478329942 0.03055645186099354 1.0 0.36133004325624857 5 Q9BV23
Processive synthesis on the lagging strand -0.6373444325919022 -2.1593252344076963 0.030824943758712253 1.0 0.3614925222612619 14 P49005,P15927,P12004,P39748,P27694,P35244,Q14181,P09884
Recruitment of numa to mitotic centrosomes 0.5241414487732309 2.1519134037934484 0.03140417536258444 1.0 0.3635997316427222 37 P41208,O43805,Q9BUF5,P07437,Q13885,P04350,O95684,O75935,Q9BVA1,O94927,P61163,P68371
Processing of smdt1 0.699010126884267 2.150482086278124 0.0315171014743163 1.0 0.3635997316427222 11 Q10713,Q8NE86,Q9BPX6,Q9H300,Q8WWC4,Q9UJZ1,Q99623
Sodium calcium exchangers -0.844747533371997 -2.13698449845146 0.03259925246317952 1.0 0.3730511229455785 1 P30626
Tyrosine catabolism -0.8435867672663674 -2.130695023385495 0.033114275345920596 1.0 0.3748200453940495 1 P16930
Assembly and cell surface presentation of nmda receptors 0.6940803521336817 2.124741901287828 0.03360815506875614 1.0 0.3748200453940495 11 Q9BUF5,Q13885,P04350,Q12959,Q9BVA1,P07196
Complex i biogenesis 0.5516023615402463 2.1234748986127023 0.03371407674594895 1.0 0.3748200453940495 28 Q9NPL8,Q86Y39,O75438,O95168,O75306,P03886,Q9H845,Q16718,Q9P0J0,Q9Y6M9,O96000,O43676
Bicarbonate transporters 0.8328496807893199 2.1223255924320275 0.03381040578607353 1.0 0.3748200453940495 1
Phospholipid metabolism 0.4797435014650698 2.1103148556425766 0.03483124484323685 1.0 0.37768899034342507 48 Q8N2A8,Q9NPH0,Q10713,Q96N66,Q8IV08,P35790,Q8NCC3,Q9NQZ5,Q9NP80,P43304
Autophagy 0.47755861209795863 2.109804994867174 0.034875156066372925 1.0 0.37768899034342507 51 P21796,Q8IWA4,Q9BUF5,Q7Z3C6,Q15388,O94826,P04350,Q13885,P08670,Q9NS69,Q8N4H5,Q9BVA1,Q96FZ7
Interleukin 3 interleukin 5 and gm csf signaling -0.6647245403746253 -2.107312709227949 0.03509048242380697 1.0 0.37768899034342507 11 P22681,P07947,P63104,Q06124,P46109,P17612
A tetrasaccharide linker sequence is required for gag synthesis 0.8299477655252455 2.106812223001536 0.03513385956683024 1.0 0.37768899034342507 1
Nucleotide biosynthesis -0.6385796564895065 -2.0984890773062412 0.03586196378492712 1.0 0.3806930943006256 13 P30566,P31939,P22234,P22102,P27708,P49915,P30520,P12268,P11172
Carboxyterminal post translational modifications of tubulin 0.8241939489925724 2.0953140225667712 0.03614308674982669 1.0 0.3806930943006256 6 Q13885,P04350,Q9BUF5,Q9BVA1
Chondroitin sulfate biosynthesis 0.827626233313986 2.094392020977377 0.03622507296482613 1.0 0.3806930943006256 1
Rho gtpases activate iqgaps 0.6764920160049549 2.0914645421242017 0.03648644173705784 1.0 0.3806930943006256 12 Q13885,P04350,Q9BUF5,Q9BVA1
Met receptor recycling -0.930960693255604 -2.087875606544222 0.03680905713203941 1.0 0.3812558545282038 4 P62330,P46109
Regulation of expression of slits and robos -0.3962043632381232 -2.0797545187155206 0.037548054690814237 1.0 0.38609195366858984 125 P83731,P62424,P30050,P42766,P62280,P32969,P62277,P62910,P62906,P62333,P28066,O00487,P27635,P46779,P55036,Q07020,P15170,P62269,Q9UNM6,O00232,P15880,P26373,P25786,Q86U70,P05388,P18621,Q02878,P63220,P83881,Q99460,P62249,P18124,Q02543,P62857,P49207,P62917,O75832,Q15287,P50914,P60866,P61247,P40429,P46782,P62753,Q15369,P84098,P62701,P61313,P25789,P46777,P43686,Q15370,P62241,Q9HAU5,P36578,P35998,Q13200,O14818,P47914,P08865,O00233,P46776,P61927
Processive synthesis on the c strand of the telomere -0.6461159995306168 -2.073764207995019 0.03810121477181272 1.0 0.38896132202303774 12 P49005,P15927,P12004,P39748,P27694,P35244
Gap junction trafficking and regulation 0.6824493129661582 2.0637054130699877 0.03904565581445141 1.0 0.3957556114336182 11 Q13885,P04350,Q9BUF5,Q9BVA1
Activation of ampk downstream of nmdars 0.7525229009252086 2.050323937587292 0.040332830168119616 1.0 0.40335303977229564 8 Q13885,P04350,Q9BUF5,Q9BVA1
Regulation of tlr by endogenous ligand -0.8282066163667745 -2.0471029158678333 0.04064798075224685 1.0 0.40335303977229564 1 P09429
Irak4 deficiency tlr2 4 -0.8282066163667745 -2.0471029158678333 0.04064798075224685 1.0 0.40335303977229564 1 P09429
Rhoj gtpase cycle 0.5502026317738511 2.01346605574972 0.044065622492444056 1.0 0.43422998831095916 26 P02786,P42167,O96013,Q8TAA9,P27105,Q86YQ8
Synthesis of glycosylphosphatidylinositol gpi 0.8102147417295394 2.000984520554689 0.0453940580770511 1.0 0.444235644216107 1
Copi dependent golgi to er retrograde traffic 0.46598158263020467 1.9943232344389121 0.046116741691117236 1.0 0.4458534500982691 50 P24390,Q9BUF5,Q92845,Q15363,Q13885,P04350,Q9BVA1,Q9P2W9,Q9Y3B3,O43731
Tnf signaling -0.6975095511990417 -1.9936732173119902 0.04618777812857333 1.0 0.4458534500982691 9 O14920,P63244,Q96BN8
Post chaperonin tubulin folding pathway 0.6955013913296232 1.9894500127698964 0.046651554049953914 1.0 0.44728753511408514 10 Q13885,P04350,Q9BUF5,Q15813
Ldl clearance -0.6162182992577039 -1.9800269904486292 0.047700495947643695 1.0 0.45277466828566615 13 P01130,P38571
Fceri mediated ca 2 mobilization 0.7545081473322263 1.9783434280573873 0.04788997704016995 1.0 0.45277466828566615 7
Caspase activation via dependence receptors in the absence of ligand -0.8151479976784409 -1.975767677881105 0.04818109577951768 1.0 0.45277466828566615 1 P42574
Metabolic disorders of biological oxidation enzymes -0.7821358004103701 -1.9683767037891176 0.04902471031406286 1.0 0.45718482023731816 6 P51580,P23526,P48507,P22570,P48506
G alpha 12 13 signalling events -0.625385287677536 -1.9660332562115113 0.049294769201063904 1.0 0.45718482023731816 12 P62873,Q12802,Q7Z628,P61586
Downstream signal transduction -0.7081011715388894 -1.942780145209152 0.05204272784499042 1.0 0.47088200823791243 8 P46109,P16333,Q06124
Signaling by pdgf -0.7081011715388894 -1.942780145209152 0.05204272784499042 1.0 0.47088200823791243 8 P46109,P16333,Q06124
Signaling by robo receptors -0.39134943593516947 -1.9388041498285693 0.05252519063359706 1.0 0.47088200823791243 143 P83731,P62424,P30050,P42766,P62280,P32969,P62277,P62910,P61586,P62906,P62333,P28066,O00487,P27635,P46779,P17612,P55036,Q07020,P15170,P62269,Q9UNM6,O00232,Q13459,P15880,P26373,P25786,Q86U70,P05388,P18621,P07737,Q02878,P63220,P83881,Q99460,P62249,P18124,Q02543,P62857,P49207,P62917,O75832,P16333,Q15287,P50914,P60866,P61247,P40429,P46782,P61927,P62753,Q15369,P84098,P62701,P61313,P25789,P46777,P43686,Q15370,P50552,P62241,Q9HAU5,P36578,P35998,Q13200,O14818,P47914,P08865,O00233,P46776,Q01518
Downregulation of tgf beta receptor signaling -0.7285735550947773 -1.938297206788443 0.05258697299818538 1.0 0.47088200823791243 7 Q9Y3F4,P62136,Q9UNE7,P62140,Q9Y5K5
Apoptosis induced dna fragmentation -0.6578512462479145 -1.933556100422269 0.05316772917927626 1.0 0.47088200823791243 10 P09429,P10412,Q14974,P42574,P16403,O00273,P07305
Formation of atp by chemiosmotic coupling 0.7104639751628329 1.9328769525346003 0.05325135769313838 1.0 0.47088200823791243 9 O75947,O75964,P06576,P56385
Rac2 gtpase cycle 0.485160126246768 1.9325809710992339 0.053287838444860736 1.0 0.47088200823791243 40 P02786,P42167,O96013,Q86Y07,P50402,Q13505,O15173,Q86XL3
Synthesis of pa 0.7263746795238288 1.926924930792011 0.05398898602044233 1.0 0.47088200823791243 8 Q8N2A8,Q9NPH0,Q9HCL2,P43304
Signaling by gpcr -0.4131694375082357 -1.9244357184299787 0.05429999090225612 1.0 0.47088200823791243 51 P62873,Q12802,Q9BV23,P62136
Ldl remodeling 0.7948345908299452 1.9181328364523846 0.055094169785296465 1.0 0.47088200823791243 1
Chylomicron assembly 0.7948345908299452 1.9181328364523846 0.055094169785296465 1.0 0.47088200823791243 1
Vldl assembly 0.7948345908299452 1.9181328364523846 0.055094169785296465 1.0 0.47088200823791243 1
Transport of connexons to the plasma membrane 0.8346891342242869 1.915589215418638 0.055417403365561224 1.0 0.47088200823791243 5 Q13885,P04350,Q9BUF5,Q9BVA1
Gap junction assembly 0.8346891342242869 1.915589215418638 0.055417403365561224 1.0 0.47088200823791243 5 Q13885,P04350,Q9BUF5,Q9BVA1
Synthesis of pyrophosphates in the cytosol 0.7907719094602409 1.8962002206790594 0.05793357402380739 1.0 0.48933179487965883 1
Pexophagy -0.7974463145675887 -1.8785765780421837 0.06030233175232391 1.0 0.5021326418648339 1 Q13315
Cell extracellular matrix interactions -0.6729302369803036 -1.877777348624636 0.06041163022235829 1.0 0.5021326418648339 9 Q14315,P50552,P05556,P21333,Q13418,P49023,Q96AC1
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7720360218017802 1.86958332699669 0.06154170237841705 1.0 0.5021326418648339 6 Q9NR77,Q16850
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s -0.4067123978617129 -1.8641631361294055 0.06229879845832609 1.0 0.5021326418648339 50 P62280,P62277,P62269,O15371,P15880,Q14240,P63220,P62249,P62857,P60842,P08708,P60866,P41091,P46781,P46782,Q9UBQ5,P62753,P62701,P62241,Q13347,P56537,P08865,P61247
Influenza infection -0.37234305146490493 -1.8506353195428102 0.06422203494235523 1.0 0.5021326418648339 124 P83731,P62424,P30050,P42766,P62280,P32969,P62277,P62910,P62906,P62487,P46779,P27635,Q07020,P62269,P15880,P78406,Q14974,P26373,P05388,P18621,Q02878,P63220,P83881,P62249,P18124,Q02543,P62857,O00505,P49207,P62917,P08708,P35269,O15514,P50914,P60866,P61247,P46781,P40429,P46782,P62753,P84098,P62701,P61313,P46777,P62826,P62241,P36578,P47914,P08865,P46776,P61927
Signaling by tgf beta receptor complex -0.5204465758801357 -1.848923555219544 0.06446885186183726 1.0 0.5021326418648339 21 P28482,P22681,Q9Y3F4,P49336,P62136,P61586,Q13547,P61081,Q93008,O75376,Q9UNE7,P62140,Q9Y5K5
Metabolism of lipids 0.46102087839886463 1.847306075721548 0.06470279289212177 1.0 0.5021326418648339 195 Q9UBM7,Q9NPH0,P49327,P30536,P37268,P51648,P50897,P35790,Q15392,Q8NCC3,P23786,Q96G23,Q15165,P43304,Q53GQ0,O95470,Q8N2A8,O76062,P48449,Q8IV08,P38435,Q16836,O00116,Q15800,Q16850,P27544,Q13503,P10619,Q9UMR5,P49748,Q9NQZ5,P07602,Q9BY49,Q14914,P33527,O75845,Q10713,Q8IVS2,Q06136,Q15067,Q9NZ01,P04062,O43772,Q9NP80,Q16880
Binding and uptake of ligands by scavenger receptors 0.7075115652831747 1.8368891872422533 0.06622625585344166 1.0 0.5021326418648339 8 Q8WTV0
N glycan trimming and elongation in the cis golgi 0.7777132907719062 1.825586683506057 0.0679125431676173 1.0 0.5021326418648339 1
Polb dependent long patch base excision repair -0.7033578529385356 -1.8241433532274702 0.06813040282845328 1.0 0.5021326418648339 7 Q9NX46,Q86W56,Q9UGN5,P39748,P27695
Ephb mediated forward signaling -0.5454279085532849 -1.8201280384930876 0.0687395086234841 1.0 0.5021326418648339 17 Q13464,Q92747,P07947,P60953,P59998,P61586,O15145,O00401,P61158,P63000,O75116,P23528,O15143
Dopamine clearance from the synaptic cleft 0.7765525246662764 1.8193021893499373 0.06886533956682861 1.0 0.5021326418648339 1
Rhobtb1 gtpase cycle 0.5606900397658738 1.8183940837626238 0.06900392196926797 1.0 0.5021326418648339 19 P38159,P78371,P62995,P08670,P07910,O43396
Class a 1 rhodopsin like receptors 0.7192781843457221 1.8152412133949227 0.06948684870726796 1.0 0.5021326418648339 7 P07602,Q9BYT8,P42892
Peptide ligand binding receptors 0.7192781843457221 1.8152412133949227 0.06948684870726796 1.0 0.5021326418648339 7 P07602,Q9BYT8,P42892
Signaling by csf3 g csf -0.6324986212566258 -1.8085359965737469 0.07052311963101054 1.0 0.5021326418648339 10 Q15369,Q15370,Q06124
Rac3 gtpase cycle 0.47080237096783595 1.8083388322989984 0.07055378159637482 1.0 0.5021326418648339 40 P02786,P42167,O96013,Q86Y07,P50402,O15173,Q9UQB8
Transport of inorganic cations anions and amino acids oligopeptides 0.6850643541729038 1.8078541292058479 0.0706292065938916 1.0 0.5021326418648339 9 P30825,Q70HW3
Transport of small molecules 0.4399381626145714 1.799359777931437 0.07196178775741724 1.0 0.5021326418648339 157 P02786,P21796,P08183,Q13438,P45880,P30825,Q8WTV0,P30519,P49721,Q9Y487,Q70HW3,P60900,P53985,P28072,Q8NEW0,Q14997,P09601,O15118,Q9UBX3,Q93050,P28070,Q8WWC4,Q8TB61,Q10713,Q9HD20,Q99797,Q8N4V1
Class b 2 secretin family receptors -0.9720331622472523 -1.7958481552272547 0.07251866972052579 1.0 0.5021326418648339 2 P62873
Slc transporter disorders 0.49692572756737113 1.7956447815512486 0.07255102900618793 1.0 0.5021326418648339 32 Q92621,P08195,P53985,Q8N1F7,Q8NFH5,P57740,Q7Z3B4,P35613,Q8NFH4,Q9BTX1
Purine ribonucleoside monophosphate biosynthesis -0.629831992860132 -1.7953315986531646 0.07260088342301607 1.0 0.5021326418648339 10 P30566,P31939,P22102,P49915,P30520,P20839,P12268,P22234
Signaling by erythropoietin -0.8564647338301529 -1.7923605074061961 0.07307523663618865 1.0 0.5021326418648339 4 P46109
Intrinsic pathway of fibrin clot formation 0.9608899368969342 1.7849747997039065 0.07426540454827091 1.0 0.5021326418648339 2
Cellular hexose transport 0.7698781195589052 1.7831450041365762 0.0745627021350399 1.0 0.5021326418648339 1
Peroxisomal lipid metabolism 0.6184836875679907 1.7745855760369678 0.07596634060352425 1.0 0.5021326418648339 12 Q15067,Q9BY49
Activated ntrk2 signals through frs2 and frs3 -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Tie2 signaling -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Met activates ptpn11 -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Pi 3k cascade fgfr1 -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Frs mediated fgfr4 signaling -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Pi 3k cascade fgfr4 -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Stat5 activation downstream of flt3 itd mutants -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Signaling by flt3 itd and tkd mutants -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Pi 3k cascade fgfr3 -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Frs mediated fgfr3 signaling -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Stat5 activation -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Frs mediated fgfr2 signaling -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Pi 3k cascade fgfr2 -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Frs mediated fgfr1 signaling -0.9667291018582783 -1.773670733293758 0.07611763015390016 1.0 0.5021326418648339 2 Q06124
Alpha oxidation of phytanate 0.800530090426816 1.773031525825128 0.07622348308076266 1.0 0.5021326418648339 5 Q9BY49
Activation of nmda receptors and postsynaptic events 0.5224506827401051 1.7718358167590689 0.07642181517404101 1.0 0.5021326418648339 25 Q9BUF5,P51812,Q13885,P04350,P27361,Q14168,Q12959,Q9BVA1,P07196
Runx1 and foxp3 control the development of regulatory t lymphocytes tregs -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Runx1 regulates transcription of genes involved in differentiation of keratinocytes -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Runx1 regulates transcription of genes involved in bcr signaling -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Runx1 regulates transcription of genes involved in interleukin signaling -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Runx1 regulates transcription of genes involved in wnt signaling -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Runx3 regulates immune response and cell migration -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Runx2 regulates chondrocyte maturation -0.7777132907718847 -1.7696322021268884 0.07678843078553133 1.0 0.5021326418648339 1 Q13951
Hiv elongation arrest and recovery -0.4955462513551645 -1.7661244072660445 0.07737497952164984 1.0 0.5036472290881703 23 Q15370,O15514,Q08945,Q9Y5B0,P62487,Q15369,Q9H3P2
Serine biosynthesis -0.9845673788223919 -1.7451689165126965 0.0809554701783799 1.0 0.5245470875941601 3 P78330,Q9Y617
Synthesis of udp n acetyl glucosamine -0.7844276583381822 -1.7356794488229823 0.08262052926805952 1.0 0.5321013274257638 5 Q16222,Q96EK6,O95394,Q06210,Q9UJ70
Heme degradation 0.8416455138185261 1.731330315663982 0.08339286741602403 1.0 0.5321013274257638 4 P30519,P09601
Tnfr1 induced nfkappab signaling pathway -0.7269687076809463 -1.7306337641067655 0.08351710566567272 1.0 0.5321013274257638 6 O14920,P63244
Signaling by tgfb family members -0.49563006203003335 -1.7300503502130575 0.08362127978572609 1.0 0.5321013274257638 22 P28482,P22681,Q9Y3F4,P49336,P62136,P61586,Q13547,P61081,Q93008,O75376,Q9UNE7,P62140,Q9Y5K5
Kinesins 0.5400729343421753 1.7138456624672924 0.08655707467262652 1.0 0.5483236114306118 20 Q9BUF5,Q92845,Q13885,P04350,Q9BVA1,P68371
Molybdenum cofactor biosynthesis -0.7771053241894019 -1.705124940369774 0.08817112505429892 1.0 0.5554264434347895 5 O96007,Q9NQX3,Q9Y697,O95396
Pecam1 interactions -0.833851051795073 -1.7013047681532787 0.0888857730921977 1.0 0.5554264434347895 4 Q06124,P07947
Glycosphingolipid metabolism 0.566787798380353 1.699286822192208 0.08926515428855963 1.0 0.5554264434347895 16 P10619,P17900,Q9NZJ7,P04062,P07602,Q16880
Interconversion of nucleotide di and triphosphates -0.49612878521706727 -1.6985449436659976 0.08940495761453038 1.0 0.5554264434347895 21 P22392,P32321,Q9NRF8,P35754,Q13232,P00390,Q16881,P33316,P00568,P15531,P23921
Trna aminoacylation -0.42778438669788255 -1.6973240320976568 0.08963541617094206 1.0 0.5554264434347895 36 O43324,P54136,Q15181,P23381,Q9H2U2,P41252,Q15046,Q5T160,P26639,P47897,P07814,P26640,O43776,P49591,P54577,P49588
Glutathione conjugation -0.5614825135499596 -1.6864475834599297 0.09170962296027585 1.0 0.5658084999157887 13 Q8WUX2,P10768,P48507,P14550,P21266,P48506
Metabolism of porphyrins 0.6599280737579989 1.6825311438439605 0.09246589100693803 1.0 0.566603890525792 9 P09601,P30519,P33527,P22830
Ampk inhibits chrebp transcriptional activation activity 0.7510156703424217 1.6808065264968963 0.0928005005521495 1.0 0.566603890525792 1
Heparan sulfate heparin hs gag metabolism 0.828838080180506 1.679593471949678 0.09303643868393907 1.0 0.566603890525792 4 P54802,Q7LGA3
Hiv transcription elongation -0.45031117630833334 -1.6743355701950302 0.09406466754892895 1.0 0.5704177916749152 28 Q15370,O15514,Q08945,Q9Y5B0,P62487,Q15369,Q9H3P2
Tp53 regulates transcription of cell cycle genes -0.5189020175931015 -1.6658585018025036 0.09574160071937698 1.0 0.5781163039182806 17 Q99873,P20248,Q9Y3B8,P12004,Q9H9A5,O75175,O14965
Fatty acid metabolism 0.42346411551240504 1.6533955222553625 0.09825039358020526 1.0 0.5901917123870282 60 P40939,P49327,P51648,P50897,P23786,Q15165,Q53GQ0,Q9H7Z7,Q16836,P09960,Q9UMR5,P49748,Q9BY49,Q14914,P33527,Q8IVS2,Q15067,Q9NZ01,O43772
Tp53 regulates transcription of death receptors and ligands 0.928708814895528 1.6518102141029005 0.09857324583208293 1.0 0.5901917123870282 2
Phosphate bond hydrolysis by nudt proteins -0.9587868827082676 -1.646846837082954 0.09958953150153094 1.0 0.590883754653705 3 P36639
Metabolism of water soluble vitamins and cofactors -0.4092623500870691 -1.646037332087033 0.09975607322506641 1.0 0.590883754653705 39 O96007,P05165,P11498,Q96RQ3,Q8NCW5,O00763,Q13085,Q96CD2,P50747
Golgi associated vesicle biogenesis 0.4852471133095235 1.6451540058955032 0.0999380557553835 1.0 0.590883754653705 29 P02786,Q9H3P7,Q9Y5X3,P11717,O75976,O60749,Q9Y5X1,P55327
Transcription of e2f targets under negative control by dream complex -0.7030998154262611 -1.6265531232382062 0.10383204210209263 1.0 0.6091890391516455 6 Q13547,Q09028,P12004,Q99741
Sialic acid metabolism 0.7654834366858186 1.6250569318185248 0.10415042855687129 1.0 0.6091890391516455 5
The role of gtse1 in g2 m progression after g2 checkpoint 0.42695862618977715 1.624252112127498 0.10432201304711053 1.0 0.6091890391516455 51 P60900,P28070,Q13885,P04350,P28072,P49721,Q14997
Glycogen metabolism -0.5942460975623867 -1.6183457954438918 0.10558809653575207 1.0 0.6126213225206486 10 Q16851,P13807,P11216,Q6PCE3,P36871,P10253,Q04446,P35573
Cell cell communication -0.43906530140260025 -1.6162077260332062 0.10604940892662218 1.0 0.6126213225206486 29 Q14315,P50552,P16333,P05556,P21333,Q13418,Q06124,O00401,P49023,Q96AC1
Erythropoietin activates ras -0.9505890384824701 -1.6154884248876065 0.10620496500357968 1.0 0.6126213225206486 3 P46109
Traf6 mediated irf7 activation in tlr7 8 or 9 signaling -0.7486941381311434 -1.608488546776076 0.10772822261640425 1.0 0.6188920967314884 1 Q13404
Protein methylation -0.6539277199780528 -1.5978625267149646 0.11007357544277774 1.0 0.6298161433600872 7 P15880,P38117,O60678,P55072,O60870,P13639
Sumoylation of rna binding proteins 0.4742183814941292 1.5952644593149334 0.11065310967285891 1.0 0.63058940813569 31 Q92621,Q8IXK0,Q8N1F7,P07910,Q8NFH5,Q7Z3B4,P57740,Q9BTX1,Q8NFH4,P61978
Role of phospholipids in phagocytosis 0.7573414115503592 1.5904589067183361 0.11173140133685155 1.0 0.6341874339879695 5 O43865
Arachidonate production from dag -0.942498923278583 -1.584503999169913 0.11307907229893344 1.0 0.6370489353186229 3 Q9BV23
Ripk1 mediated regulated necrosis 0.5747865624796509 1.5824646381943008 0.1135435387851138 1.0 0.6370489353186229 13 P41440
Rhoh gtpase cycle 0.49071530062645974 1.58229444489717 0.1135823683126227 1.0 0.6370489353186229 26 P02786,Q9UNZ2,O96013,Q8TAA9,P27105
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.6388018812145327 1.576038355647921 0.11501696404912498 1.0 0.6425554015185367 9 Q9UJX2,Q96DE5,Q9UJX3
Hats acetylate histones -0.4648564326696607 -1.5712821719257708 0.11611712042949063 1.0 0.6461576230958713 23 Q96EB1,P51610,O96019,Q9Y4A5,Q8WYH8,Q6IA86,Q15014,Q9Y265,O75529,Q96ES7,O95163,P61964
Transcriptional activation of mitochondrial biogenesis 0.5621039034260675 1.5649078098327718 0.11760452721209336 1.0 0.6518782191951581 14 P00367,P06576,P48735
Fasl cd95l signaling 0.9068963810096747 1.5613172913613018 0.11844890574419997 1.0 0.6530333269558414 2
Abacavir transport and metabolism 0.9066061052477008 1.5601123559175911 0.11873333217378934 1.0 0.6530333269558414 2
Pyruvate metabolism 0.5362535110294244 1.556470635320209 0.1195962200716707 1.0 0.6530480588682704 17 P21796
Resolution of ap sites via the multiple nucleotide patch replacement pathway -0.4624785973572333 -1.5562172328081139 0.11965644489482052 1.0 0.6530480588682704 23 Q9NX46,P49005,Q86W56,Q9UGN5,P15927,P12004,P27694,P39748,P35251,P35244,P35250,P27695,P35249
Phenylalanine and tyrosine metabolism -0.7973849259271725 -1.553406721350841 0.12032599816619749 1.0 0.6541861739380622 4 Q7L266,P16930,P09417
Cargo trafficking to the periciliary membrane 0.5065849993800502 1.5496431345867094 0.12122719381935276 1.0 0.6565701833193189 22 A6NIH7,O43924
Intraflagellar transport 0.568663373379892 1.5469488412302543 0.12187558233666951 1.0 0.6575720583107758 13 A0AVF1,Q9BUF5,Q92845,Q13885,P04350,Q9BVA1,P68371
Hedgehog off state 0.4174726368647834 1.540860971488738 0.12335062634941729 1.0 0.663009616628118 53 P60900,P28070,Q13885,P04350,P28072,P49721,Q14997
Erythrocytes take up carbon dioxide and release oxygen 0.724608241439347 1.5373787454696286 0.12420058814196855 1.0 0.6650589983903901 1
Ras processing 0.6942008785325786 1.5236993242463934 0.12758383835663167 1.0 0.6736581182192912 6 O60725,P49356,O43924
Formation of rna pol ii elongation complex -0.41057101917021505 -1.5230393293413511 0.12774886612184666 1.0 0.6736581182192912 34 Q15370,O15514,Q08945,Q9Y5B0,P62487,Q15369,Q9H3P2
Platelet adhesion to exposed collagen -0.9070534510842466 -1.5227124015226126 0.12783067392328773 1.0 0.6736581182192912 2 P05556
Peroxisomal protein import 0.5025237898666793 1.5214080140198945 0.12815747902228147 1.0 0.6736581182192912 22 Q2T9J0,O75874,Q15067,Q6QHF9,Q9BY49
Mapk1 erk2 activation -0.7895080700982737 -1.5213174566385197 0.12818019162734928 1.0 0.6736581182192912 4 P28482,Q06124
Glutathione synthesis and recycling -0.678475602214834 -1.5186016500467097 0.12886279556399893 1.0 0.6747465199458099 6 P48506,P48507,Q8WUX2,Q96KP4
Tristetraprolin ttp zfp36 binds and destabilizes mrna -0.5195237035236143 -1.515413599686038 0.1296676955013174 1.0 0.6751854186832703 14 Q9NPI6,Q92973,Q9NPD3,Q9NQT4,Q9Y3B2,Q8IZH2,Q06265,Q9Y2L1,Q5RKV6,Q13868
Translation of sars cov 1 structural proteins 0.7395260802087514 1.5145032435467056 0.12989825179741565 1.0 0.6751854186832703 5 Q13724,Q10472
Intra golgi and retrograde golgi to er traffic 0.3790488316728018 1.5110133588645165 0.13078504732513618 1.0 0.6773138034830958 98 P11717,P49755,Q7Z6M1,Q9P2W9,Q9Y3B3,P24390,Q92845,Q10472,P04350,O00461,O95249,O43731,P61163,P68371,Q8TBA6,Q8TD16,Q9BUF5,Q13561,Q13885,Q9UJW0,O75935,O15260,Q9BVA1,Q6NUQ1,Q15363,Q13190
Attachment and entry -0.7292513058618467 -1.5000943218866587 0.13358997157811636 1.0 0.6822085459628427 1 P55072
Synthesis of pc 0.6889612909411806 1.5000845579610145 0.13359250043915916 1.0 0.6822085459628427 6 P35790
Signaling by met -0.4733605799063892 -1.4975264786953635 0.1342563210611174 1.0 0.6822085459628427 19 Q99961,P05556,P22681,Q06124,P62330,P46109,Q96P70
Negative regulation of mapk pathway -0.5358836389148757 -1.4938046328957448 0.13522669028362433 1.0 0.6822085459628427 12 Q02750,P28482,P53041,P30086
Synthesis of wybutosine at g37 of trna phe -0.9001451378809223 -1.4935372716545678 0.1352966054711977 1.0 0.6822085459628427 2 O60294,Q32P41
Recycling pathway of l1 0.5027442061468986 1.492124908123114 0.13566640323113988 1.0 0.6822085459628427 21 P51812,Q13885,P04350,Q9BUF5
Calnexin calreticulin cycle 0.6505805804798662 1.4899679488984556 0.13623266355067454 1.0 0.6822085459628427 7 Q9NYU2,Q13438
Vitamin b2 riboflavin metabolism 0.7156123041207171 1.488553085022738 0.1366050934795766 1.0 0.6822085459628427 1
Maturation of sars cov 2 spike protein 0.5761638197353381 1.4866869061330537 0.13709752255579488 1.0 0.6822085459628427 11 Q16706,Q13724,P04843,Q9H0U3,P46977,P27824
Cooperation of pdcl phlp1 and tric cct in g protein beta folding -0.5442462967063162 -1.486158647525846 0.13723716263868813 1.0 0.6822085459628427 11 P49368,P19784,P48643,P50991,P62873,P40227
Hs gag degradation 0.888478053762136 1.484854617807891 0.13758233996941271 1.0 0.6822085459628427 2
G0 and early g1 -0.5906574250440885 -1.4844793180867581 0.13768180594329582 1.0 0.6822085459628427 9 P20248,Q99741,P24941,P12004,Q13547,Q09028
Regulation by c flip 0.7801466167773164 1.4815467714892048 0.1384609311045093 1.0 0.6822085459628427 4
Caspase activation via death receptors in the presence of ligand 0.7801466167773164 1.4815467714892048 0.1384609311045093 1.0 0.6822085459628427 4
Notch2 intracellular domain regulates transcription -0.7248984329657355 -1.4757999966589221 0.1399975916577918 1.0 0.6831666599342436 1 Q04721
Defective lfng causes scdo3 -0.7248984329657355 -1.4757999966589221 0.1399975916577918 1.0 0.6831666599342436 1 Q04721
Anchoring of the basal body to the plasma membrane 0.4515091928644519 1.4731303882208615 0.1407158808641784 1.0 0.6831666599342436 34 P41208,Q15051,O43805,P07437,P04350,O95684,O75935,O94927,P61163,P68371
Extension of telomeres -0.4029456375270072 -1.4691560328683557 0.14179047259066557 1.0 0.6831666599342436 34 P27694,Q14181,P35250,P49005,P20248,P15927,P24941,P35244,P09884,P40938,P54132,P12004,P39748,P35251,Q8WVB6,O00743,Q9Y265,O60832,P40937,Q5H9R7,P35249
Acyl chain remodelling of pc 0.8844677967100649 1.4682084154129968 0.1420476190608908 1.0 0.6831666599342436 2
Metabolism of vitamins and cofactors -0.35853415025927715 -1.4678768180116717 0.14213768622652845 1.0 0.6831666599342436 49 O96007,P05165,P11498,P01130,Q96RQ3,Q8NCW5,O00763,Q13085,Q96CD2,P50747
Synthesis of dolichyl phosphate 0.8841799709724381 1.4670137716648886 0.14237230905285103 1.0 0.6831666599342436 2 Q86YN1
Mrna editing c to u conversion 0.7115496227510133 1.4665190753607615 0.14250692835837642 1.0 0.6831666599342436 1
Common pathway of fibrin clot formation 0.7109692396981985 1.4633723916842383 0.1433655089022423 1.0 0.6848465905396985 1
Rhoq gtpase cycle 0.4743010886317165 1.460034284575978 0.14428065163204695 1.0 0.6848465905396985 26 P02786,O96013,Q8TAA9,P27105,Q86YQ8
Rhoa gtpase cycle 0.40888146052354124 1.4599448321793072 0.1443052364844044 1.0 0.6848465905396985 54 Q9P0I2,P02786,P42167,Q8TAA9,P30519,P27105,Q15904,Q96HY6,P41440,O75955,O15173
Trna modification in the nucleus and cytosol -0.48246096120042625 -1.4537058910953855 0.14602786420639458 1.0 0.6879059556495846 17 Q9H974,Q9NX74,Q9UBP6,O60294,Q32P41
Inactivation of csf3 g csf signaling -0.6033137286914946 -1.453082511342528 0.14620084614735385 1.0 0.6879059556495846 8 Q15369,Q15370,Q93034,P42224
Tysnd1 cleaves peroxisomal proteins 0.6783930587883327 1.4523503024402555 0.14640422734755076 1.0 0.6879059556495846 6 Q2T9J0,Q15067
Signaling by mapk mutants -0.8891016755126064 -1.4468723158453611 0.14793268808404214 1.0 0.688772948588083 2 P28482
Regulation of pten localization 0.879052295869368 1.4457336890107018 0.14825191136660476 1.0 0.688772948588083 2
Telomere maintenance -0.3571528332714892 -1.4408535733852224 0.1496260545293726 1.0 0.688772948588083 45 P27694,P62487,Q14181,P35250,P20248,P49005,P15927,P24941,P35244,P09884,P40938,O15514,P54132,P12004,P39748,P35251,Q8WVB6,O00743,Q9Y265,O60832,P19387,Q5H9R7,P35249
Transport of bile salts and organic acids metal ions and amine compounds 0.9000577176519634 1.4387092964979074 0.1502329042734134 1.0 0.688772948588083 3 P53985
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 0.7215485087219302 1.4375505632607122 0.15056161644517996 1.0 0.688772948588083 5
Purinergic signaling in leishmaniasis infection 0.7213935534995541 1.436886132805681 0.15075035081807275 1.0 0.688772948588083 5
The nlrp3 inflammasome 0.7213935534995541 1.436886132805681 0.15075035081807275 1.0 0.688772948588083 5
Inflammasomes 0.7213935534995541 1.436886132805681 0.15075035081807275 1.0 0.688772948588083 5
Disorders of transmembrane transporters 0.38776835117742825 1.4358995523250853 0.15103092590970113 1.0 0.688772948588083 74 P08195,Q7Z3B4,P49721,Q06323,O00231,P60900,P48556,P53985,Q9BUN8,Q8NFH5,P57740,P28072,Q8NFH4,Q9BTX1,Q14997,P12270,P28070,Q8N1F7,P35613,Q92621,P20618,Q13438
Butyrate response factor 1 brf1 binds and destabilizes mrna -0.514864936244472 -1.4344542426870783 0.15144267791365884 1.0 0.688772948588083 13 Q9NPI6,Q9NQT5,Q9NPD3,Q9NQT4,Q9Y3B2,Q8IZH2,Q06265,Q9Y2L1,Q5RKV6,Q13868
Formation of fibrin clot clotting cascade 0.8961983133137257 1.4239782836036832 0.15445275856416707 1.0 0.6934164711704849 3
Metabolism of amino acids and derivatives -0.3529667952392121 -1.423776746506994 0.15451110909915378 1.0 0.6934164711704849 192 P83731,P62424,P62906,P28066,P27635,Q9BV20,Q07020,Q9UNM6,P08865,O00232,P25786,P10515,Q02543,P49591,P49207,O75832,P25325,P60866,P30038,Q53H96,Q6NVY1,P62753,P62701,P54136,P24752,Q15046,P47914,P47897,O00233,P31937,P30050,Q9UBQ7,P62333,O00487,P00505,P07814,P00390,P62269,P23526,Q02878,P63220,Q99460,P12277,P62857,P62917,P09417,P40429,P46782,P17174,P84098,P61313,P25789,P36578,P35998,O43252,P61247,P61927,P42766,P62280,P32969,P62910,P49189,P55036,P15880,P41252,P05388,P18621,P83881,P62249,Q99714,P78330,P50914,Q7L266,Q9Y617,P16930,P62241,Q96RQ3,P49419,Q14353,O43324,P62277,P46779,Q16881,P26373,P12532,P52788,Q96C36,P46777,P43686,P30084,Q13200,O14818,P18124,P19623,P46776
O linked glycosylation 0.7658854899250833 1.4232366674129493 0.1546675594302993 1.0 0.6934164711704849 4 Q10472,O43505
Glycogen synthesis -0.6566243174849037 -1.422470732469943 0.1548896420741095 1.0 0.6934164711704849 6 Q16851,P13807,Q6PCE3,P36871,Q04446
Regulation of mecp2 expression and activity -0.5122055589856694 -1.420095307654867 0.1555799361788961 1.0 0.6934164711704849 13 Q9BZK7,P42858,Q13555,Q96ST3,P17252,Q9HCE1,Q92769,Q13547,O75376,Q9UPQ9,P17612
Transcriptional regulation by mecp2 -0.4838401949712405 -1.4165518988588846 0.15661398031020823 1.0 0.6934164711704849 16 Q9BZK7,P42858,Q13555,Q96ST3,P17252,Q9HCE1,Q92769,Q13547,O75376,Q9UPQ9,P17612,Q14353
Acyl chain remodelling of pg 0.7019733023795687 1.4146387037617263 0.15717445479602743 1.0 0.6934164711704849 1
Gaba b receptor activation -0.7632397727740449 -1.4140394499645121 0.15735031974411284 1.0 0.6934164711704849 4 P62873
Gaba receptor activation -0.7632397727740449 -1.4140394499645121 0.15735031974411284 1.0 0.6934164711704849 4 P62873
Adp signalling through p2y purinoceptor 12 -0.7632397727740449 -1.4140394499645121 0.15735031974411284 1.0 0.6934164711704849 4 P62873
Resolution of abasic sites ap sites -0.4113447927498334 -1.4103752609609572 0.15842890628510187 1.0 0.6956363903589471 28 Q9NX46,P49005,Q86W56,Q9UGN5,P15927,P12004,P27694,P39748,P35251,P35244,P35250,P27695,P35249
Galactose catabolism -0.7620082251465394 -1.4090021761934362 0.15883452464855452 1.0 0.6956363903589471 4 P51570,Q14376
Fcgr activation -0.8780548855270216 -1.400175757682605 0.1614606934377909 1.0 0.7024135104688192 2 P07947
Ptk6 regulates proteins involved in rna processing 0.8679245283018915 1.3995783614982804 0.16163961746545108 1.0 0.7024135104688192 2 P23246
Cell death signalling via nrage nrif and nade -0.5081861778903358 -1.3984065706579683 0.16199101116019898 1.0 0.7024135104688192 13 P42574,Q7Z628,Q12802
Biosynthesis of specialized proresolving mediators spms 0.8673439767779382 1.3971716253117663 0.16236196718377216 1.0 0.7024135104688192 2 Q14914
Copi mediated anterograde transport 0.3998333296987847 1.3924658324416654 0.16378138124269204 1.0 0.7064005470619453 58 P24390,Q9BUF5,Q13561,Q15363,Q08379,Q13885,P04350,Q9UJW0,P49755,Q14789,O43731,O75935,Q9BVA1,O95249,Q9Y3B3,P61163,P68371
Tp53 regulates transcription of dna repair genes -0.39474473050919096 -1.3902441480652603 0.16445475154232425 1.0 0.7071554316319942 33 Q15370,O15514,P38398,Q08945,Q9Y5B0,P62487,P55199,Q15369,Q9H3P2
Cdc42 gtpase cycle 0.42353425069263917 1.3881063419405655 0.16510466570746352 1.0 0.7075971740786742 40 P02786,P42167,O96013,P27105,Q86YQ8,Q9UQB8
Metabolism of rna -0.16834363125942978 -1.386629394102982 0.16555480041868909 1.0 0.7075971740786742 487 P83731,P62424,P62906,P28066,P27635,Q99575,Q32P41,Q07020,Q96DI7,Q9UNM6,P54105,O00232,P78406,P25786,O43143,P18124,P78346,Q02543,P49207,P60842,O75832,Q16539,P60866,Q14692,Q9NQT4,Q9H9A5,P62753,P62701,Q9UQ35,Q9ULX3,P47914,O00233,P30050,Q9Y3C6,Q9UBP6,Q8IV48,P62333,O00487,O60294,P07814,P56182,P62269,Q9NX74,Q9NPD3,Q02878,P63220,Q99460,Q9Y2P8,P62857,P62917,Q9Y3I0,Q9UNP9,P40429,P46782,Q96F86,P84098,P61313,P25789,P55769,O43447,P35998,P36578,Q9Y224,P61247,P61927,P42766,Q9BQA1,P62280,P32969,Q6P2E9,P62910,O94992,P62487,Q9Y2L1,Q5SY16,P55036,P15170,P15880,P05388,P18621,Q14240,P83881,P62249,Q9BQ52,Q8TEQ6,Q99714,Q15287,Q9NPI6,O15514,P50914,Q05655,O43148,O43592,O95059,O75818,Q9UL46,P62826,Q9NXF1,Q9NXG2,P62241,Q15366,O60832,Q92499,O75691,P16383,P19387,P62888,Q13243,P63151,Q96C86,Q92973,Q92917,P62277,Q05519,P46779,Q15477,Q9Y606,Q9NYH9,Q9H9L3,P26373,O94906,P62318,P08708,P35269,Q13601,Q9NV06,P63104,P39687,Q9Y2X3,P46781,Q8ND04,Q86W42,Q5TAX3,Q5RKV6,P46777,P43686,P26196,Q9BV38,Q96J01,Q9NRX1,Q9H974,Q9HAU5,Q15365,Q14137,Q13200,O14818,O75175,P08865,P46776
Activation of gene expression by srebf srebp 0.4908224607177641 1.3824764355653707 0.1668254609901012 1.0 0.710067356685455 20 Q9UBM7,P49327,O76062,P37268,P48449,Q16850
Downregulation of erbb4 signaling 0.8630989649742069 1.3795781558538758 0.16771656700642756 1.0 0.710067356685455 2
Regulation of kit signaling -0.6997310369612816 -1.3793982547140957 0.16777199707889956 1.0 0.710067356685455 5 P22681,P07947
Synthesis of gdp mannose -0.8728592162553829 -1.37821195089214 0.16813785851244423 1.0 0.710067356685455 2 Q96IJ6,P34949
Chromosome maintenance -0.34490715463811106 -1.3712123013378792 0.17030878457442378 1.0 0.710067356685455 51 P27694,P62487,Q14181,P35250,P20248,P49005,P15927,P24941,P35244,P09884,P40938,O15514,P54132,P12004,P39748,P35251,Q09028,Q8WVB6,O00743,Q9Y265,O60832,P19387,Q5H9R7,P35249
Signaling by mst1 -0.7060359837492537 -1.3704941529572165 0.17053269936652016 1.0 0.710067356685455 1 Q13043
Signaling by fgfr4 -0.6046273603863933 -1.3701619868789459 0.17063634152906282 1.0 0.710067356685455 7 P28482,P22681,Q06124
Signaling by fgfr1 -0.6046273603863933 -1.3701619868789459 0.17063634152906282 1.0 0.710067356685455 7 P28482,P22681,Q06124
Signaling by fgfr3 -0.6046273603863933 -1.3701619868789459 0.17063634152906282 1.0 0.710067356685455 7 P28482,P22681,Q06124
Base excision repair -0.39717253853639645 -1.3674107859944586 0.17149658341947926 1.0 0.7109421271214302 31 Q9NX46,P49005,Q86W56,Q9UGN5,P15927,P12004,P27694,P39748,P35251,P35244,P35250,P27695,P35249
Transport of the slbp dependant mature mrna 0.4476814571493865 1.3662389587906545 0.17186397310692425 1.0 0.7109421271214302 30 Q92621,P12270,Q86V81,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Synthesis of pg 0.8806643182716911 1.3646928540202552 0.17234960657489218 1.0 0.7109421271214302 3 Q8N2A8
Phosphorylation of the apc c 0.5454469500545609 1.3609556185961282 0.17352771526003585 1.0 0.7137270375477996 12 Q9UJX2,Q96DE5,Q9UJX3
Trans golgi network vesicle budding 0.4352390937215438 1.3587470298271491 0.17422676369556678 1.0 0.7145311493757492 35 O43493,P02786,Q9H3P7,Q9Y5X3,O14964,P11717,O75976,Q14789,Q9BXS5,Q9Y5X1,O60749,P50570,Q10567,P55327,P05067,P09496,P51809
Signaling by hedgehog 0.3946584915406943 1.3530677103217748 0.17603400003892378 1.0 0.7169164044475747 60 Q9BUF5,P60900,P28070,Q13885,P04350,P28072,P49721,Q14997
Apc c cdc20 mediated degradation of cyclin b 0.5522693120827121 1.3526965513704914 0.17615259263217542 1.0 0.7169164044475747 11 Q9UJX2,Q96DE5,Q9UJX3
Met activates rap1 and rac1 -0.6932941404913666 -1.3521602748570716 0.17632404873305396 1.0 0.7169164044475747 5 P46109
Ion transport by p type atpases -0.5162934484255904 -1.3407795780447402 0.17999202858488195 1.0 0.7238557207488882 11 Q9NTM9
Signal amplification -0.5982540907109763 -1.3406924927151669 0.180020312988024 1.0 0.7238557207488882 7 Q16539,P62873,Q13685
Recruitment of mitotic centrosome proteins and complexes 0.43754572283397947 1.3362712150859113 0.18146064142116392 1.0 0.7238557207488882 33 P41208,O43805,P07437,P04350,O95684,O75935,O94927,P61163,P68371
Telomere c strand lagging strand synthesis -0.4267931983010025 -1.3318204624569492 0.18291919223993958 1.0 0.7238557207488882 23 P49005,P15927,P12004,P27694,P39748,P35251,P35244,Q14181,P35250,P09884,Q8WVB6,P35249
Rrna modification in the nucleus and cytosol -0.3344759138872791 -1.3311317529552533 0.1831456625622374 1.0 0.7238557207488882 58 P62263,P78316,P46087,Q9NX24,Q9NYH9,Q14690,P15880,Q9Y5J1,Q9Y6V7,Q9Y2R4,Q15061,Q9UI30,Q9H6R4,Q9H0S4,O00567,Q9Y2P8,O00566,Q9NV06,Q13601,P62081,Q14692,Q9Y2X3,Q969X6,P46781,Q9H8H0,P55769,Q9UNQ2,Q9NXG2,Q9NRX1,Q9Y3A2,O60832,O75691,Q12788,P62753,O00425
Insulin receptor recycling 0.5692965270545942 1.3277570847833526 0.18425836844392984 1.0 0.7238557207488882 10 Q93050,Q9Y5K8,Q9Y487
Insulin processing 0.5690569493675544 1.3264661667000686 0.18468533470802884 1.0 0.7238557207488882 10
Protein ubiquitination -0.4198812351430758 -1.3206276247708977 0.1866255571329849 1.0 0.7238557207488882 24 P60604,P68036,P12004,Q14527,A0AVT1,Q93008,Q96BN8,P22314
Regulation of glucokinase by glucokinase regulatory protein 0.4556700242260885 1.3197346006717108 0.18692364346644075 1.0 0.7238557207488882 26 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Signaling by scf kit -0.5560640207662383 -1.3183398740332846 0.18738989851900456 1.0 0.7238557207488882 9 P22681,P07947,P17252,Q06124,P40763,P42224,P63000
Synthesis of pips at the late endosome membrane -0.7396784509085479 -1.3176059277246681 0.1876356002333972 1.0 0.7238557207488882 4 Q13614,Q08AM6
Synthesis of leukotrienes lt and eoxins ex 0.8675958188153261 1.31484975315847 0.18856040253415962 1.0 0.7238557207488882 3 Q14914,P33527
Negative regulation of fgfr2 signaling -0.6317118083162809 -1.3127175619389782 0.18927813759644385 1.0 0.7238557207488882 6 P28482,P22681,Q06124
Negative regulation of fgfr3 signaling -0.6317118083162809 -1.3127175619389782 0.18927813759644385 1.0 0.7238557207488882 6 P28482,P22681,Q06124
Negative regulation of fgfr1 signaling -0.6317118083162809 -1.3127175619389782 0.18927813759644385 1.0 0.7238557207488882 6 P28482,P22681,Q06124
Negative regulation of fgfr4 signaling -0.6317118083162809 -1.3127175619389782 0.18927813759644385 1.0 0.7238557207488882 6 P28482,P22681,Q06124
Spry regulation of fgf signaling -0.6317118083162809 -1.3127175619389782 0.18927813759644385 1.0 0.7238557207488882 6 P28482,P22681,Q06124
Interleukin 37 signaling -0.8714809598233149 -1.3115711028773973 0.18966488845396734 1.0 0.7238557207488882 3 P43378,Q06124
Dna strand elongation -0.3914733573063761 -1.3110281005355306 0.18984827000603066 1.0 0.7238557207488882 30 P49005,Q9Y248,P15927,P12004,P27694,P39748,P35251,P35244,Q14181,P35250,P09884,Q9BRX5,O75419,P35249
Cytosolic iron sulfur cluster assembly -0.5918186198444995 -1.310948063723238 0.189875310903858 1.0 0.7238557207488882 7 Q6FI81,Q9Y5Y2,Q96T76,Q9Y3D0
Golgi to er retrograde transport 0.37678226786751845 1.3095854600016414 0.1903361098667773 1.0 0.7238557207488882 74 P49755,Q9P2W9,Q9Y3B3,P24390,Q92845,Q10472,P04350,O43731,P68371,P61163,Q8TD16,Q9BUF5,Q13561,Q13885,Q9UJW0,O75935,Q9BVA1,O15260,Q6NUQ1,Q15363
Signaling by bmp -0.6941381311665498 -1.304111688500108 0.19219550418677755 1.0 0.7238557207488882 1 Q7Z3T8
Translocation of slc2a4 glut4 to the plasma membrane 0.41742923343478583 1.303703050021759 0.1923348491052821 1.0 0.7238557207488882 39 Q9BUF5,Q92845,Q13885,P04350,Q9UIQ6,Q9BVA1
Downstream signaling of activated fgfr4 -0.8694174133604844 -1.3036358432221482 0.19235777360193285 1.0 0.7238557207488882 3 Q06124
Downstream signaling of activated fgfr1 -0.8694174133604844 -1.3036358432221482 0.19235777360193285 1.0 0.7238557207488882 3 Q06124
Downstream signaling of activated fgfr2 -0.8694174133604844 -1.3036358432221482 0.19235777360193285 1.0 0.7238557207488882 3 Q06124
Downstream signaling of activated fgfr3 -0.8694174133604844 -1.3036358432221482 0.19235777360193285 1.0 0.7238557207488882 3 Q06124
Mrna decay by 5 to 3 exoribonuclease -0.5528996236225429 -1.3031818415631706 0.1925126879235477 1.0 0.7238557207488882 9 P26196,Q6P2E9,Q96F86,Q9NPI6
Rhobtb gtpase cycle 0.4431873096202283 1.3022698764377583 0.19282414548490467 1.0 0.7238557207488882 28 P38159,P78371,P62995,P08670,P07910,O43396
Tp53 regulates transcription of genes involved in g2 cell cycle arrest -0.5700330978045426 -1.2963268616683317 0.19486289793303357 1.0 0.7263184605227626 8 Q99873,Q9Y3B8,O14965,P12004
Nrage signals death through jnk -0.5296926342775278 -1.2960956945344622 0.19494251812927388 1.0 0.7263184605227626 10 Q7Z628,Q12802
Synthesis of diphthamide eef2 -0.6798552660835301 -1.2952883419287236 0.19522077933724935 1.0 0.7263184605227626 5 P13639,Q9BQC3,Q9H2P9
Formation of xylulose 5 phosphate -0.8670150987224792 -1.2943991294364108 0.1955275912048593 1.0 0.7263184605227626 3 Q00796,Q7Z4W1,P14550
Organic anion transporters 0.8412596588217811 1.2892392284909482 0.19731493101776443 1.0 0.7303317059793399 2
Aurka activation by tpx2 0.43149678013596077 1.2859433402362719 0.19846283653850416 1.0 0.7303317059793399 33 P41208,O43805,P07437,Q13561,P04350,O95684,O75935,O94927,P61163,P68371
Proton coupled monocarboxylate transport 0.8403806543399636 1.2856109682181311 0.19857886692198257 1.0 0.7303317059793399 2
Signaling by erbb2 -0.46753659555771004 -1.2829990343401265 0.19949241439175136 1.0 0.7303317059793399 15 Q96RT1,P07947,P61586,Q05655,Q93034,Q9UNE7
Integration of energy metabolism -0.4086199196119933 -1.2826062253803918 0.1996300680412404 1.0 0.7303317059793399 25 P29401,O00763,Q13085,P37837,P62873
Lagging strand synthesis -0.43300620882992497 -1.282417995157967 0.19969605491189846 1.0 0.7303317059793399 20 P49005,P15927,P12004,P27694,P39748,P35251,P35244,Q14181,P35250,P09884,P35249
Vitamin d calciferol metabolism 0.8570341508527484 1.274611185199781 0.20244689652110281 1.0 0.7360967423558674 3 P38435
Cobalamin cbl vitamin b12 transport and metabolism 0.7292975735623066 1.2733658544735087 0.20288824807422756 1.0 0.7360967423558674 4 Q99707,P33527
Abortive elongation of hiv 1 transcript in the absence of tat -0.4512128742482531 -1.2732673567787072 0.20292318604422688 1.0 0.7360967423558674 17 P62487,Q9H3P2,O15514,Q9Y5B0
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain -0.5644369639127507 -1.2700310790881828 0.20407355975827768 1.0 0.7360967423558674 8 Q9H9A5,O75175
Regulation of cholesterol biosynthesis by srebp srebf 0.4489640627306136 1.2688776791017762 0.2044846944345624 1.0 0.7360967423558674 26 Q9UBM7,P49327,O76062,P37268,P48449,Q16850
Phase 0 rapid depolarisation -0.6877539175855867 -1.2685301013012884 0.20460870817831278 1.0 0.7360967423558674 1 Q13555
Urea cycle 0.8360398302458769 1.2677042026913377 0.20490360340420555 1.0 0.7360967423558674 2
Antigen activates b cell receptor bcr leading to generation of second messengers 0.6776342386322025 1.2487354487577866 0.21176185074889942 1.0 0.7481268982286375 5
Plasma lipoprotein clearance -0.46123870947693707 -1.2480253745200254 0.21202176489204283 1.0 0.7481268982286375 15 P01130,P38571
Synthesis of bile acids and bile salts via 24 hydroxycholesterol 0.6706326175275682 1.2457829419607584 0.21284409367409163 1.0 0.7481268982286375 1
Sumoylation of sumoylation proteins 0.4409188030586132 1.24459943559926 0.21327902795237685 1.0 0.7481268982286375 27 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Sumoylation of ubiquitinylation proteins 0.4409188030586132 1.24459943559926 0.21327902795237685 1.0 0.7481268982286375 27 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Metabolism of steroid hormones 0.6766042520049449 1.2442999465815563 0.2133891907093055 1.0 0.7481268982286375 5 P30536
Translation -0.3338750146016101 -1.2439738299939613 0.21350919473617624 1.0 0.7481268982286375 220 P83731,P62424,P61011,P49770,P62906,P26639,P27635,Q07020,P23381,Q96DV4,P18124,Q02543,P49591,P49207,P60842,P09132,P60866,Q9BYC9,Q9BZE1,P62753,P62701,P54577,P54136,Q13347,Q7Z7H8,Q15046,P56537,P47914,P47897,P30050,P60468,P07814,P26641,P62269,P43897,Q5T160,Q02878,Q05639,P63220,P26640,O43776,P62857,P62917,P41091,P40429,P46782,Q9UBQ5,Q7Z2W9,P84098,P61313,P36578,P13798,Q9H2U2,P13639,P61247,P61927,P42766,P62280,P32969,P62910,P15170,O15371,Q15181,P15880,P41252,P05388,P18621,Q14240,P83881,P62249,P50914,Q5T653,P49588,P62241,Q9H2W6,Q14232,O43324,P62277,Q13144,P46779,P26373,P46199,P46777,Q9Y399,O76094,P08865,P46776
Myd88 independent tlr4 cascade -0.3969764033248751 -1.2424645643364034 0.21406520691871855 1.0 0.7481268982286375 26 Q8IV63,P28482,P09429,Q16539,P51452,Q06124,Q15418,O14920,Q02750,Q13404
Downregulation of erbb2 erbb3 signaling 0.8298899794587428 1.242368211999464 0.21410073846949462 1.0 0.7481268982286375 2
Metabolism of polyamines 0.4075128043852223 1.2420784490643637 0.2142076190745985 1.0 0.7481268982286375 40 P60900,P28070,Q6QHF9,P28072,P49721
Creatine metabolism -0.8533681765389691 -1.2419627784768859 0.21425029553260067 1.0 0.7481268982286375 3 P12532,Q14353,P12277
Maturation of sars cov 1 spike protein 0.721260482617653 1.2404440759942488 0.2148111869555791 1.0 0.7481268982286375 4 Q13724
Myoclonic epilepsy of lafora -0.6822402785838458 -1.2378321692802512 0.21577829762150813 1.0 0.7481268982286375 1 P13807
Unfolded protein response upr 0.3965192976114545 1.2331005688274552 0.21753824528372534 1.0 0.7481268982286375 43 Q9Y5M8,O76024,P43307,Q9NWM8,P49748,O43731
Processing of dna double strand break ends -0.3683987145082781 -1.2307076125271674 0.2184322398997396 1.0 0.7481268982286375 34 P27694,P35250,Q9NY27,P20248,P15927,P24941,O60921,P35244,P60510,Q13315,P40938,O95714,P54132,Q92547,Q9H9A7,Q9HAW4,P38398,P40937,Q14676,P35249
Metabolism of nitric oxide nos3 activation and regulation -0.5740713758428705 -1.2290510132126309 0.21905268015690416 1.0 0.7481268982286375 7 O00401,O75608,Q9Y314,O95865
Dna repair -0.30119071208623804 -1.2253659071466647 0.22043738629118836 1.0 0.7481268982286375 125 P52701,P49916,Q9UGN5,Q9C0B1,Q04323,P27694,Q7L5N1,Q14258,Q5UIP0,P62487,P35250,Q16531,P20248,P49005,Q9NX46,Q9NY27,O96019,P15927,P24941,O60921,P13010,Q86WJ1,P35244,P60510,P55199,Q14676,Q13315,P40938,Q9UNP9,Q13620,O15514,O95551,O95714,Q9NUW8,P61201,P12004,P54132,Q14694,P39748,P35251,P55072,Q92547,Q9H9A7,Q9H1I8,Q9NZJ0,O43542,Q86W56,Q9HAW4,P38398,Q9Y265,P25490,Q16658,P29372,P40937,P19387,P27695,P53041,P35249
Rhobtb2 gtpase cycle 0.4712716182248188 1.2249136450460552 0.22060775871965266 1.0 0.7481268982286375 19 P38159,P78371,P07910,P62995
Neurotransmitter receptors and postsynaptic signal transmission 0.417004146318244 1.2244984691529797 0.22076424345335122 1.0 0.7481268982286375 36 Q9BUF5,P51812,Q13885,P04350,Q14168,Q12959,Q9BVA1,P07196
Zbp1 dai mediated induction of type i ifns -0.6115354335214106 -1.223919925502921 0.22098243614358792 1.0 0.7481268982286375 6 O14920
Rip mediated nfkb activation via zbp1 -0.6115354335214106 -1.223919925502921 0.22098243614358792 1.0 0.7481268982286375 6 O14920
Cell junction organization -0.4349965847774273 -1.2231340673537214 0.22127906324793623 1.0 0.7481268982286375 18 Q14315,P50552,P05556,P21333,Q13418,P49023,Q96AC1
Endosomal vacuolar pathway 0.8434959349593223 1.2231188549712608 0.22128480807155504 1.0 0.7481268982286375 3 P10321,Q9UIQ6
Ub specific processing proteases 0.36681928173065625 1.2227875591048796 0.221409945581045 1.0 0.7481268982286375 76 P21796,P60900,P45880,Q15388,P28070,P49721,P28072
G alpha s signalling events -0.6112639723341111 -1.2227267802165582 0.2214329085666158 1.0 0.7481268982286375 6 P62873
Formation of the early elongation complex -0.4222361790624624 -1.2182463193674362 0.22313038255525175 1.0 0.7520712894201953 20 P62487,Q9H3P2,O15514,Q9Y5B0
Formation of tubulin folding intermediates by cct tric 0.5125216547100905 1.2167619716821418 0.22369479270609838 1.0 0.752186992535435 13 P78371,Q13885,P04350,Q9BUF5
Transcription of the hiv genome -0.37173920547085537 -1.2150537315677663 0.22434559877484617 1.0 0.7525919731950513 32 Q15370,O15514,Q08945,Q9Y5B0,P62487,Q15369,Q9H3P2
Gpvi mediated activation cascade -0.6083201585826776 -1.2097916135512041 0.226358865081963 1.0 0.7557931003280333 6 P61586,P63000,Q06124,P60953
Pcna dependent long patch base excision repair -0.4250604616706634 -1.2095816449881576 0.2264394648359649 1.0 0.7557931003280333 19 P49005,P15927,P12004,P27694,P39748,P35251,P35244,P35250,P27695,P35249
Nuclear envelope breakdown 0.3972816979799719 1.2074881536103605 0.2272442045567653 1.0 0.7557931003280333 42 Q92621,P42167,Q86Y07,Q8N1F7,Q8NFH5,P57740,P50402,Q8NFH4,Q9BTX1
Prolonged erk activation events -0.6075553432839548 -1.2064321624719834 0.22765090110660458 1.0 0.7557931003280333 6 Q02750,P46109,P28482
Loss of function of mecp2 in rett syndrome -0.5685004586813828 -1.2034031059944679 0.2288203665342068 1.0 0.7557931003280333 7 Q9BZK7,Q96ST3,P17252,Q13547,O75376,P17612
Mitochondrial iron sulfur cluster biogenesis -0.7110078419982163 -1.2002787938213195 0.23003108281013285 1.0 0.7557931003280333 4 P22570,Q86SX6,Q86U28,Q9Y697
Nod1 2 signaling pathway -0.5495120060835146 -1.2000807623418346 0.23010797612220468 1.0 0.7557931003280333 8 Q15750,Q13685,Q16539,O14920,Q13404
Glycosaminoglycan metabolism 0.5095084081940058 1.1988524284856157 0.23058533212987253 1.0 0.7557931003280333 13 O43505,Q96L58,Q9P2E5,P54802,Q7LGA3,Q8TB61
Hsf1 activation -0.4616553478320086 -1.1983963867871457 0.23076273844459472 1.0 0.7557931003280333 14 P15927,P27694,P55072,P35244,Q92598
Regulation of runx1 expression and activity -0.6567632350347732 -1.1976683700007809 0.2310461476966208 1.0 0.7557931003280333 5 Q13951,Q06124,Q9UPQ9
Wax and plasmalogen biosynthesis 0.7107397413422736 1.1973794050964115 0.23115870721801723 1.0 0.7557931003280333 4
The canonical retinoid cycle in rods twilight vision -0.6741149158444383 -1.1926621374055506 0.23300171974426886 1.0 0.757912852354453 1 Q8TC12
Homology directed repair -0.3214159991850129 -1.1913752785536351 0.2335062934399117 1.0 0.757912852354453 50 P49916,Q9UGN5,P27694,P35250,Q9NY27,P20248,P49005,P15927,P24941,O60921,P35244,P60510,Q13315,P40938,O95714,P54132,P12004,P39748,P35251,Q92547,Q9H9A7,O43542,Q9HAW4,P38398,Q14676,P35249
Activation of anterior hox genes in hindbrain development during early embryogenesis -0.417597479556699 -1.1908073818040588 0.23372921032688887 1.0 0.757912852354453 20 O15514,O75530,P25490,P62487,P61964
Ca2 pathway -0.5648492333488389 -1.1866139928173716 0.2353799139500563 1.0 0.757912852354453 7 Q14571,Q08209,P17252,Q9HCE1,P62873,Q9UPQ9
Trna processing -0.3094503784347296 -1.1854169157246168 0.23585264681018692 1.0 0.757912852354453 64 P62826,Q99714,Q9H974,Q9NX74,Q9UBP6,O94992,Q92499,O60294,O43592,O95059,Q9Y3I0,Q9BQ52,O75818,Q9Y224,Q99575,Q32P41
Chrebp activates metabolic gene expression -0.6531639764590209 -1.1824784758286007 0.23701590111406778 1.0 0.757912852354453 5 O00763,Q13085
Formation of tc ner pre incision complex -0.3765020745285068 -1.1812156172585617 0.2375170787443488 1.0 0.757912852354453 28 Q16531,O15514,Q7L5N1,P62487,Q9UNP9
Ros and rns production in phagocytes 0.561870182081858 1.1809067103931907 0.23763978529495633 1.0 0.757912852354453 9 Q93050,Q9Y487
Pkmts methylate histone lysines 0.46142330362543 1.1805250738210937 0.23779144396662488 1.0 0.757912852354453 20 Q9H7B4,Q86TU7,Q03164
Synaptic adhesion like molecules 0.5860948100443266 1.1782097950773942 0.2387129785712161 1.0 0.757912852354453 7 O95197,P41440
Maturation of sars cov 2 nucleoprotein -0.7054061318492941 -1.1773900703620315 0.23903985130060046 1.0 0.757912852354453 4 Q99873,P78362,Q96SB4
Regulation of tp53 activity through association with co factors 0.8130925645744845 1.1734047110598411 0.2406335489128879 1.0 0.757912852354453 2
Map3k8 tpl2 dependent mapk1 3 activation -0.599545367985442 -1.1712811575790538 0.24148578268918675 1.0 0.757912852354453 6 O14920,Q02750
Regulation of tp53 activity -0.3128883044186228 -1.1701916394746585 0.2419238565725701 1.0 0.757912852354453 58 Q8TBX8,P19784,Q86YP4,Q92769,P27694,Q13547,P35250,Q9Y5B9,P20248,O95983,Q12873,P15927,P24941,O60921,P35244,O94776,P42771,Q13315,P40938,O60934,Q16539,P54132,Q8WYH8,Q00535,Q92547,Q9H9A7,Q09028,Q9ULW0,P38398,Q08945,P40937,Q13131,O14965,P35249
Trail signaling 0.656413232733605 1.1699127110510488 0.24203609807312176 1.0 0.757912852354453 1
Propionyl coa catabolism -0.8343064065112055 -1.16887520447979 0.2424539149050826 1.0 0.757912852354453 3 P05165
Transport of mature mrnas derived from intronless transcripts 0.4106039473917337 1.1687791052474241 0.24249264091699163 1.0 0.757912852354453 36 Q92621,P12270,Q86V81,P52298,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Cation coupled chloride cotransporters 0.6558328496807901 1.1668291625546499 0.2432793674598146 1.0 0.757912852354453 1
Signaling by leptin -0.8223990121034555 -1.165369093334496 0.2438696222053811 1.0 0.757912852354453 2 Q06124
Phase ii conjugation of compounds -0.36916691456932355 -1.1643488564775488 0.24428266472434101 1.0 0.757912852354453 30 O60701,P51580,Q8WUX2,P23526,P10768,O95861,P31153,P48507,P14550,Q96KP4,O43252,Q9NZL9,P21266,P48506,Q9Y2Q3,Q96IU4
Abacavir metabolism 0.6552524666279753 1.1637467469959775 0.24452665888717684 1.0 0.757912852354453 1
G alpha z signalling events -0.5977806374440588 -1.163545784896158 0.2446081332711687 1.0 0.757912852354453 6 Q05655,P62873
Aggrephagy 0.48121224797312145 1.1626563582119873 0.24496895488356918 1.0 0.757912852354453 16 P08670,Q13885,P04350,Q9BUF5
Plasma lipoprotein assembly remodeling and clearance -0.41692434942665657 -1.162064492445299 0.24520926918046682 1.0 0.757912852354453 19 P01130,P38571
Ras signaling downstream of nf1 loss of function variants 0.6543818920487531 1.1591252730597823 0.24640512555756944 1.0 0.757912852354453 1
Hdl clearance 0.8094756058142295 1.1586081491854856 0.24661594563835676 1.0 0.757912852354453 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5377353976783164 1.1569859603575436 0.24727809643487753 1.0 0.757912852354453 10 Q9UJX2,Q96DE5,Q9UJX3
Killing mechanisms -0.6674405107370678 -1.155634820021587 0.24783055919130814 1.0 0.757912852354453 1 P63000
Ntrk2 activates rac1 -0.6674405107370678 -1.155634820021587 0.24783055919130814 1.0 0.757912852354453 1 P63000
Activated ntrk2 signals through fyn -0.6674405107370678 -1.155634820021587 0.24783055919130814 1.0 0.757912852354453 1 P63000
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.8249259567889585 1.1527152706349508 0.24902727147407244 1.0 0.7599348348853953 3
Hcmv early events 0.38046605228107155 1.1487865736517398 0.2506439970073122 1.0 0.7627527463604138 47 Q9BUF5,P83916,Q13885,P04350,Q8N1F7,Q8NFH5,P57740,Q8NFH4,Q9BVA1,Q9BTX1
Gab1 signalosome -0.6449520640224606 -1.147861496813997 0.2510257452785858 1.0 0.7627527463604138 5 P41240,P00533,P49023,Q06124
Keratan sulfate degradation -0.6976095418759604 -1.1455667688292046 0.2519744538446058 1.0 0.7639994658237086 4 P07686
Dna double strand break repair -0.30451269981677787 -1.1428397331068512 0.25310513857655836 1.0 0.7642005127668613 63 P49916,Q9UGN5,Q04323,P27694,Q5UIP0,P35250,Q9NY27,P20248,P49005,P15927,P24941,O60921,P13010,P35244,P60510,Q13315,P40938,Q9NUW8,O95714,O95551,P54132,P12004,P39748,P35251,Q92547,Q9H9A7,O43542,Q9HAW4,P38398,P40937,Q14676,P53041,P35249
Cd28 dependent pi3k akt signaling 0.8049313580524565 1.1400487018242962 0.2542660117500628 1.0 0.7642005127668613 2
Metabolism of cofactors 0.6093907834328 1.1384180339128391 0.2549459672254297 1.0 0.7642005127668613 6 P00374
Pyruvate metabolism and citric acid tca cycle 0.4070494562923788 1.1377529319917756 0.25522366396772234 1.0 0.7642005127668613 36 Q13423,P21796,P53985,P48735
Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake -0.6639582124201788 -1.1363488315511314 0.2558106015252002 1.0 0.7642005127668613 1 P28702
Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis -0.6639582124201788 -1.1363488315511314 0.2558106015252002 1.0 0.7642005127668613 1 P28702
Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose -0.6639582124201788 -1.1363488315511314 0.2558106015252002 1.0 0.7642005127668613 1 P28702
Infectious disease -0.2076438031649587 -1.1347417872374808 0.2564835232697851 1.0 0.7646010914282038 363 P83731,P62424,O75530,P62906,P28066,Q13547,P27635,Q9BRG1,Q07020,Q9UNM6,P08865,O00232,Q12873,P07947,P78406,P25786,O94776,Q02543,P49207,O75832,P16333,Q16539,P60866,P62753,Q15369,P62701,Q09028,O00422,P28482,Q08945,P61158,P47914,O00233,Q99873,P30050,P05556,P62333,P06733,O00487,P17612,P61966,P62269,P78362,Q14974,Q96SB4,Q02878,Q93034,P63220,Q99460,P62857,P63167,P62917,O75351,P39748,P40429,P46782,P84098,Q8IZP0,P61313,P25789,P04150,Q99961,P35998,P36578,O15145,P13639,P61247,P61927,Q9BZK7,P42766,Q92747,P62280,P32969,P62910,P62487,Q9H3P2,P55036,O95983,P15880,P05388,P18621,Q14204,Q63HN8,Q02750,P83881,P62249,Q96FJ2,O15514,P50914,Q9NZZ3,Q9Y5B0,P18754,P62873,O43148,P12268,O15143,P62826,Q15370,P62241,P22681,P62277,P46779,Q16881,Q99816,Q13459,P26373,O75116,P55199,P46060,O00505,O00159,P08708,P35269,P46781,P55072,Q8WUX9,P46777,P43686,P30419,O00401,O14818,Q13200,O60551,O75376,P18124,P46776
Methionine salvage pathway 0.6948725290407997 1.1325439905261412 0.2574058008557847 1.0 0.7657417849357621 4 Q13126
Platelet sensitization by ldl -0.5900755477331546 -1.1298166724496885 0.25855348141377643 1.0 0.7667250452612275 6 Q16539,Q06124
Rnd3 gtpase cycle 0.46976524177138457 1.1278467449535483 0.2593846479633841 1.0 0.7667250452612275 17 P38159,Q07065,O75976,O43396
Diseases of programmed cell death -0.3633206573012501 -1.126843819268117 0.2598085200211253 1.0 0.7667250452612275 30 O15446,P26358,O75530,Q14181,P17655,P09884,P20810,P04632,P42771,Q09028,P32119
Recycling of eif2 gdp -0.5336229983944972 -1.1260195719079704 0.26015723508462263 1.0 0.7667250452612275 8 P41091,Q14232,P49770,Q13144
Vegfr2 mediated cell proliferation 0.6489693598401057 1.1253565752720993 0.2604379646341872 1.0 0.7667250452612275 5
Alpha protein kinase 1 signaling pathway -0.6607661056296973 -1.1186920531449573 0.2632715366096883 1.0 0.7702728050497889 1 Q15750
Irak2 mediated activation of tak1 complex -0.6607661056296973 -1.1186920531449573 0.2632715366096883 1.0 0.7702728050497889 1 Q15750
Ticam1 traf6 dependent induction of tak1 complex -0.6607661056296973 -1.1186920531449573 0.2632715366096883 1.0 0.7702728050497889 1 Q15750
Cytoprotection by hmox1 0.36628097680601934 1.1157064904407619 0.26454779143681306 1.0 0.772414230553164 68 P13073,P33527,P09601,P60900,P28070,P30519,P49721,P28072,P09669,P00403,Q14997
Nervous system development -0.3103320286353859 -1.1123455354442475 0.26598961249850817 1.0 0.7750292815921623 223 P83731,P62424,Q12955,Q14195,P62906,P28066,P27635,Q9BPU6,Q07020,Q9UNM6,P08865,O00232,P07947,P25786,Q16555,Q02543,P49207,O75832,P16333,P60866,Q16539,P62753,Q15369,P23528,P62701,O95239,P28482,P61158,P47914,O00233,P30050,P05556,P62333,O00487,P17612,P62269,Q86U70,Q02878,P63220,Q96P70,Q99460,P62857,P62917,P40429,P46782,P84098,P61313,P25789,P36578,P35998,O15145,P61247,P61927,P42766,Q92747,P62280,P32969,P62910,Q06124,P55036,P15170,Q15334,P15880,P05388,P18621,Q02750,P83881,P62249,Q15287,P50914,O15143,Q15370,P50552,P62241,P19784,P62277,P61586,P46779,Q13459,P26373,P07737,Q15418,P46777,P43686,Q9HAU5,O00401,Q13200,O15020,O14818,P18124,P46776,Q01518
Sulfur amino acid metabolism 0.5482588220731659 1.1101951825499288 0.26691492824957486 1.0 0.7758958877136912 9 Q9UBX3,Q13126
Transcriptional regulation by the ap 2 tfap2 family of transcription factors -0.5479358620440298 -1.109114912575613 0.26738061246793166 1.0 0.7758958877136912 7 P35659,Q6PL18,P10809,P25490,P46087,P00533
Metabolism of fat soluble vitamins 0.6441635298252246 1.1047038263817013 0.26928794486571395 1.0 0.7779655260582322 5 Q8N0U8,Q6NUM9
Developmental biology -0.3041805339401166 -1.1037203318883795 0.26971447308822016 1.0 0.7779655260582322 277 P83731,P62424,Q12955,Q93074,Q14195,O75530,P62906,P28066,P27635,Q9BPU6,Q07020,Q9UNM6,P08865,O00232,P07947,P49336,P25786,Q16555,Q02543,P49207,P61964,P35659,O75832,P16333,P60866,Q16539,P62753,Q15369,P23528,P62701,Q09028,O95239,P28482,P61158,P47914,Q13951,O00233,P30050,P05556,P62333,O00487,P17612,P62269,Q86U70,Q02878,P63220,Q96P70,Q99460,P62857,P62917,P40429,P46782,P84098,P61313,P25789,Q9ULK4,P36578,P25490,O15145,P35998,P61247,P61927,Q9BZK7,P42766,Q92747,P62280,P32969,P62910,Q06124,P62487,P55036,P15170,Q15334,Q15648,P15880,P05388,P18621,Q02750,P83881,P62249,Q15287,O15514,P50914,Q96EK7,P04632,O15143,Q15370,P50552,P62241,P19784,P62277,P61586,P46779,Q13459,P26373,P07737,Q15418,O60244,P46777,P43686,Q9HAU5,O00401,Q13200,O15020,O14818,O75376,P18124,P46776,Q01518
Mecp2 regulates transcription factors 0.6436448055716788 1.1023544750802186 0.27030759509121305 1.0 0.7779655260582322 1
Assembly of collagen fibrils and other multimeric structures 0.6433546140452714 1.1008263614458658 0.270972236246112 1.0 0.7779655260582322 1
Type i hemidesmosome assembly 0.6433546140452714 1.1008263614458658 0.270972236246112 1.0 0.7779655260582322 1
Plasma lipoprotein remodeling 0.7950653120464425 1.0998824940777518 0.2713833230435694 1.0 0.7779655260582322 2 Q9BU23
Diseases of carbohydrate metabolism -0.5091285937734105 -1.0952711788851504 0.2733978501480765 1.0 0.7808585988488702 9 Q7Z4W1,Q04446,P37837
Gamma carboxylation hypusine formation and arylsulfatase activation 0.4995910082401881 1.0950537016546493 0.27349311037906165 1.0 0.7808585988488702 12 O60725,P38435,Q9HA64,P49366
Rna polymerase ii transcription -0.16682616556162574 -1.0901017647759548 0.2756683190104219 1.0 0.7808703609429137 337 Q93074,Q6PL18,O75530,P28066,Q13547,Q9UNM6,P20248,O00232,Q12873,O96019,P07947,P49336,P25786,O94776,Q9UNE7,P61964,P35659,O75832,Q16539,Q9H9A5,Q92547,Q15369,Q09028,P32119,P28482,P11413,Q08945,Q86WQ0,Q13951,O00233,O14965,Q99873,Q9Y3B8,P27694,P62333,O00487,P00390,P35250,P17612,Q86U70,Q8N201,Q99460,Q13315,P12004,P25440,Q93008,P25789,P04150,P42858,Q9ULK4,P10809,P35998,P14635,P28702,P25490,P40937,P27348,Q9BZK7,Q8TBX8,Q86YP4,Q6P1J9,Q06124,O94992,P62487,Q9UPQ9,Q9Y5B9,Q9H3P2,P55036,Q9GZS3,Q15648,O95983,Q15291,P15927,P24941,P42771,P40938,P62195,Q13555,Q12824,Q15287,O15514,P54132,P51665,Q9Y5B0,O43148,Q9H9A7,Q68CP9,Q9UL46,Q15370,P38398,O94925,P19387,Q14353,Q14676,Q13243,P19784,P30044,Q05519,Q5TA45,Q68E01,Q16881,Q9NQ88,Q96P16,Q13309,O60921,P06744,P35244,P55199,P62318,Q04721,P35269,P63104,P42224,O60244,Q86W42,P43686,Q96J01,Q96EB6,Q13200,O14818,O75175,O75376,P35249
Met promotes cell motility -0.5437362996441044 -1.0899564331254503 0.27573233579479184 1.0 0.7808703609429137 7 P46109,P05556
Copi independent golgi to er retrograde traffic 0.4149032899361894 1.089284136911022 0.27602860588547506 1.0 0.7808703609429137 29 Q8TD16,Q9BUF5,Q10472,P04350,Q13885,Q9UJW0,O75935,Q9BVA1,P61163,P68371
Sumoylation of transcription factors -0.6308499720208259 -1.0885798342353716 0.2763392134973317 1.0 0.7808703609429137 5 P42771
Cellular responses to stimuli -0.19282566786604105 -1.0868437162550022 0.2771058839651819 1.0 0.7808703609429137 335 O75530,P62906,P28066,P27635,Q07020,P20248,O00232,P25786,Q02543,O75832,Q16539,P60866,Q9NQT4,Q15369,P62701,Q09028,P32119,P28482,P30041,P47914,O00233,Q8N163,P30050,Q06210,P27694,P62333,O00487,O14867,P00390,P16403,P07305,P62269,Q9NPD3,Q02878,P63220,Q99460,Q9HCU5,P62857,P63167,Q13315,P62917,P41091,P31689,P40429,P46782,P84098,P61313,P25789,P04150,Q96B36,P35998,P36578,P61247,P61927,Q9BZK7,P42766,Q99615,P62280,P32969,P62910,Q9UPQ9,Q9Y2L1,P55036,Q15648,P15880,P15927,P05388,P18621,Q14204,P83881,P62249,P10412,P42771,P47755,Q92598,Q92616,Q96FJ2,P50914,Q9NZ32,Q05655,Q15370,P62241,P34932,P19784,P62277,P46779,Q16881,Q13309,P26373,O95816,P35244,Q15418,P46777,P43686,Q96EB6,Q13200,P21283,P18124,P62753
Regulation of hmox1 expression and activity 0.37376752018183723 1.0827032345474503 0.27894016786989906 1.0 0.7808703609429137 48 P09601,P60900,P28070,P28072,P49721
Fructose metabolism -0.8026124818577175 -1.0824742138565957 0.27904186731302616 1.0 0.7808703609429137 2 Q00796,P15121
Activation of irf3 irf7 mediated by tbk1 ikk epsilon -0.8025400394840972 -1.082171677391644 0.2791762509919582 1.0 0.7808703609429137 2 Q06124
Nrif signals cell death from the nucleus 0.639582124201975 1.0809931610172834 0.27970015580270324 1.0 0.7808703609429137 1
Microrna mirna biogenesis -0.45691626735810614 -1.0794840699874428 0.28037199143213476 1.0 0.7808703609429137 12 P62826,P62487,Q9HAV4,O15514
Transcriptional regulation of white adipocyte differentiation -0.4168790144486976 -1.0793928648114663 0.2804126303670267 1.0 0.7808703609429137 17 Q15648,Q9BZK7,Q93074,Q9ULK4,P49336,Q96EK7,O60244,O75376
Dual incision in gg ner -0.3806156276386201 -1.0792713788330277 0.2804667679470767 1.0 0.7808703609429137 24 Q16531,P49005,Q9UGN5,P15927,P12004,P27694,P35251,P35244,Q86WJ1,P35250,P35249
Eph ephrin signaling -0.3421505904193725 -1.0775984134339887 0.28121301056509496 1.0 0.7808703609429137 35 Q92747,Q13464,P07947,P60953,O94973,P59998,P61586,O15145,O00401,P61158,P63000,O75116,P23528,O15143
Gpcr ligand binding 0.5417669760935373 1.0764380104797422 0.2817314105624922 1.0 0.7808703609429137 9 P07602,Q9BYT8,P42892
Regulation of tp53 activity through phosphorylation -0.3418252332632265 -1.0755196545610382 0.2821421374372821 1.0 0.7808703609429137 35 P19784,P27694,P35250,Q9Y5B9,P20248,P15927,P24941,O60921,P35244,Q13315,P40938,O60934,Q16539,P54132,Q00535,Q92547,Q9H9A7,Q9ULW0,P38398,Q08945,P40937,Q13131,O14965,P35249
Er quality control compartment erqc 0.788969521045017 1.0751625258713442 0.282301969812343 1.0 0.7808703609429137 2 Q13438
Interleukin 17 signaling -0.4013111120679424 -1.072154594721492 0.28365060063141945 1.0 0.7816580735878252 19 Q8IV63,P28482,Q16539,P51452,Q15418,O14920,Q02750,Q13404
Uptake and function of anthrax toxins -0.7997442966396479 -1.070502102168146 0.2843933632583897 1.0 0.7816580735878252 2 Q02750
Cargo recognition for clathrin mediated endocytosis 0.4014859310289316 1.0690726235215424 0.28503694640766075 1.0 0.7816580735878252 35 Q9UBC2,P02786,Q14108
Clec7a dectin 1 induces nfat activation 0.8025820043179097 1.068503201786184 0.28529358688757456 1.0 0.7816580735878252 3
Ctla4 inhibitory signaling -0.5209810356235575 -1.0675101905069204 0.28574151444823315 1.0 0.7816580735878252 8 Q06124,P07947
Homologous dna pairing and strand exchange -0.39149268966122425 -1.0633894400305963 0.28760537963656785 1.0 0.7816580735878252 21 O43542,P38398,P15927,P54132,O60921,P27694,P35244,Q92547,P40937,P35250,Q9H9A7,Q13315,P40938,P35249
Beta oxidation of butanoyl coa to acetyl coa 0.6777154966060848 1.0626844764673853 0.2879250629885499 1.0 0.7816580735878252 4 Q16836,P40939
Cdt1 association with the cdc6 orc origin complex 0.38107002807365536 1.053435861452808 0.2921412755375119 1.0 0.7816580735878252 42 P60900,Q9Y619,P28070,P28072,P49721
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 -0.6224307252783973 -1.0533150536487674 0.29219662182627393 1.0 0.7816580735878252 5 P20248,Q13547,Q09028
Diseases associated with o glycosylation of proteins 0.7833206154955685 1.0523277498524037 0.2926492042912492 1.0 0.7816580735878252 2
Intrinsic pathway for apoptosis -0.38505391869614713 -1.0513271977642684 0.2931083397801233 1.0 0.7816580735878252 22 P30419,P28482,Q9Y3B8,P63104,P27348,P42574,P42771,P63167,Q16611,Q96FJ2
Ptk6 expression -0.7949196528636707 -1.0503930497672944 0.29353743979727454 1.0 0.7816580735878252 2 P04150
Mitotic g2 g2 m phases 0.3416038073975053 1.0496960079985516 0.2938578997219534 1.0 0.7816580735878252 96 P41208,Q9BUF5,P60900,P07437,Q99640,P28070,Q13885,P04350,O95684,P28072,P49721,O75935,O94927,Q14997
Cellular response to hypoxia 0.3804581943607246 1.0475959025224262 0.29482482608736915 1.0 0.7816580735878252 42 Q9Y241,P60900,P28070,P28072,P49721
Hcmv infection 0.36804062672994187 1.0472648170727148 0.2949774581135225 1.0 0.7816580735878252 56 Q9BUF5,P83916,Q13885,P04350,Q8N1F7,Q8NFH5,P57740,Q9BTX1,Q8NFH4,Q9BVA1,P61978,Q96FZ7
Nuclear receptor transcription pathway -0.571013533078212 -1.0467690777036727 0.29520609537284925 1.0 0.7816580735878252 6 P04150,Q15648,Q86WQ0,P28702,O75376
Activation of puma and translocation to mitochondria 0.6329077190946045 1.046058874939129 0.29553385092331474 1.0 0.7816580735878252 1
Activation of noxa and translocation to mitochondria 0.6329077190946045 1.046058874939129 0.29553385092331474 1.0 0.7816580735878252 1
Runx3 regulates cdkn1a transcription 0.6329077190946045 1.046058874939129 0.29553385092331474 1.0 0.7816580735878252 1
Toll like receptor 9 tlr9 cascade -0.3746273334790146 -1.0437411636931178 0.2966051594351269 1.0 0.7816580735878252 24 Q8IV63,P28482,P09429,Q16539,P51452,Q15418,O14920,Q02750,Q13404
Toll like receptor tlr1 tlr2 cascade -0.37915275393226217 -1.0431106783597384 0.29689703562811376 1.0 0.7816580735878252 23 Q8IV63,P28482,P09429,Q16539,P51452,Q15418,O14920,Q02750,Q13404
Tp53 regulates transcription of cell death genes 0.6297192501319512 1.0427425338271152 0.2970675528513649 1.0 0.7816580735878252 5 P49327
Adrenaline noradrenaline inhibits insulin secretion -0.8009707696026496 -1.0418204990374371 0.2974949083542744 1.0 0.7816580735878252 3 P62873
Runx3 regulates wnt signaling 0.6314567614625675 1.0384923204104668 0.2990409087440893 1.0 0.7816580735878252 1
Binding of tcf lef ctnnb1 to target gene promoters 0.6314567614625675 1.0384923204104668 0.2990409087440893 1.0 0.7816580735878252 1
Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0.6314567614625675 1.0384923204104668 0.2990409087440893 1.0 0.7816580735878252 1
Beta oxidation of hexanoyl coa to butanoyl coa 0.6285680127010158 1.037813052601887 0.29935709884395667 1.0 0.7816580735878252 5 Q16836,P40939
Adora2b mediated anti inflammatory cytokines production -0.49675510026303404 -1.0374252215031416 0.2995377290432346 1.0 0.7816580735878252 9 P62873
Mitochondrial fatty acid beta oxidation of unsaturated fatty acids -0.6709953257179802 -1.0373740090762507 0.29956158638216035 1.0 0.7816580735878252 4 P11310
Ptk6 promotes hif1a stabilization -0.6459663377829192 -1.037156048880412 0.2996631374431127 1.0 0.7816580735878252 1 P00533
Erbb2 activates ptk6 signaling -0.6459663377829192 -1.037156048880412 0.2996631374431127 1.0 0.7816580735878252 1 P00533
Nucleotide excision repair -0.29247916397531915 -1.0311763271542687 0.30245813974860747 1.0 0.7875011014738973 58 Q16531,P49005,Q9UGN5,O15514,P15927,P12004,Q9Y265,P27694,Q7L5N1,P62487,P35251,P35244,Q86WJ1,P25490,P35250,P55199,P35249,Q9UNP9
Signaling by mras complex mutants -0.7973151079768247 -1.027970986764871 0.30396347556326164 1.0 0.7886782391990472 3 P62140
Raf independent mapk1 3 activation -0.512352948612845 -1.0278469140851823 0.30402184414508726 1.0 0.7886782391990472 8 Q02750,P28482,Q06124
Phenylalanine metabolism -0.7967298241137786 -1.0257555010520922 0.3050068459821631 1.0 0.7893345656210825 3 Q7L266,P09417
Attachment of gpi anchor to upar 0.7909495545784593 1.0249487530494348 0.30538736894008056 1.0 0.7893345656210825 3 Q92643
Collagen formation 0.49342091134518234 1.018640372808886 0.30837372997906254 1.0 0.7944935051949489 11 O60568,P07237,O75718,Q32P28
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.4586525455175436 1.018367974392987 0.3085031158297511 1.0 0.7944935051949489 16 Q9BUF5,P78371,Q13885,P04350,Q9BVA1,P68371
Foxo mediated transcription -0.4438404162029183 -1.0128845550441425 0.31111530650160013 1.0 0.7997692389959612 12 P04150,P04179,Q96ST3,Q96EB6,Q9Y3B8,P61981,P63104,Q92769,Q13547,P27348
Striated muscle contraction 0.5811303050252741 1.0096981161486613 0.3126399453080304 1.0 0.8002000436906631 6 P08670,P09493
Gluconeogenesis -0.38598897005788585 -1.0081649805017785 0.3133752666282592 1.0 0.8002000436906631 20 P11498,P40926,P53007,P60174,P06733,P09972,P04075
Inhibition of dna recombination at telomere -0.44233619164922944 -1.005285495419937 0.31475939732497427 1.0 0.8002000436906631 12 P62487,O15514
Epigenetic regulation of gene expression -0.29549774341478907 -1.0049758712165864 0.31490846853582966 1.0 0.8002000436906631 47 Q86YP4,O43159,O75530,Q92769,Q13547,Q9GZS1,Q9UIG0,O15446,O95983,Q12873,Q9BQG0,Q3B726,O94776,O95602,O00159,P35659,P17480,Q09028,O00422,Q96T88,Q96EB6,P26358
Regulation of pten stability and activity 0.37278648602872927 1.004010905038099 0.31537335732635996 1.0 0.8002000436906631 43 P60900,P28070,P28072,P49721,P46934
Caspase activation via extrinsic apoptotic signalling pathway 0.620277543800831 1.0023624993598386 0.3161685470342883 1.0 0.8002000436906631 5
Interleukin 6 signaling -0.5607508242671453 -1.0023611823072924 0.31616918290522733 1.0 0.8002000436906631 6 P22681,Q06124,P40763,P42224,P29597
Interleukin 6 family signaling -0.5607508242671453 -1.0023611823072924 0.31616918290522733 1.0 0.8002000436906631 6 P22681,Q06124,P40763,P42224,P29597
Ret signaling -0.5606601237246389 -1.0019698456772606 0.31635815680793655 1.0 0.8002000436906631 6 P17612,Q06124
Tak1 activates nfkb by phosphorylation and activation of ikks complex -0.5232312611417981 -0.9970541868755947 0.3187382087090702 1.0 0.804121320296437 7 Q15750,P09429,Q04206,O14920,Q13404
Dna damage bypass -0.36173090996774426 -0.9958710137431386 0.319312820687941 1.0 0.804121320296437 25 Q9NZJ0,Q16531,P49005,Q13620,P15927,P12004,P27694,P35251,Q14258,P55072,P35244,P40937,P35250,Q14694,P40938,P35249
Antigen processing cross presentation 0.36461624662773684 0.9947442437493649 0.31986067007881 1.0 0.804121320296437 51 P60900,P28070,Q9UIQ6,P28072,P49721
Signal transduction by l1 -0.44801283987133195 -0.9926299349001744 0.32089033105950504 1.0 0.804121320296437 11 P28482,Q02750,P05556,P19784
Synthesis of pe 0.7819997405441067 0.991602507334669 0.32139146569403976 1.0 0.804121320296437 3 P35790
Signaling by the b cell receptor bcr 0.3641854432267778 0.9902998897154677 0.3220275604752856 1.0 0.804121320296437 51 P60900,O43865,P28070,P28072,P49721
Uptake and function of diphtheria toxin -0.6588797892370275 -0.9884406541937805 0.3229368854599537 1.0 0.804121320296437 4 P13639,Q16881
Protein protein interactions at synapses 0.4537136554619785 0.9867289163452698 0.32377555034885797 1.0 0.804121320296437 16 O95197,Q14168,Q12959,P41440
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 -0.5568551975700515 -0.9855725436343934 0.3243429168186871 1.0 0.804121320296437 6 Q14258,O14920
Arachidonic acid metabolism 0.5350586330210897 0.9833775613368546 0.3254216496611577 1.0 0.804121320296437 8 Q14914,P33527,P09960,Q9H7Z7,Q15165
Mitochondrial trna aminoacylation -0.3993183310903637 -0.9832678535780908 0.32547562714348865 1.0 0.804121320296437 17 Q5T160,Q9H2U2,Q15046,P26640
Interactions of vpr with host cellular proteins 0.39550151543841267 0.9832341462152283 0.3254922127240836 1.0 0.804121320296437 33 Q92621,P12270,Q12769,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,P12236,Q9BTX1,P12235
P75ntr signals via nf kb -0.7782991827509547 -0.9814430369153562 0.32637431191930677 1.0 0.804121320296437 2 O14920
Nf kb is activated and signals survival -0.7782991827509547 -0.9814430369153562 0.32637431191930677 1.0 0.804121320296437 2 O14920
Sumoylation of intracellular receptors -0.7782823204879503 -0.981373368061068 0.32640865432751776 1.0 0.804121320296437 2 P04150
Export of viral ribonucleoproteins from nucleus 0.4022715501145643 0.9775247900161681 0.3283094111113043 1.0 0.8045224329360506 28 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Collagen biosynthesis and modifying enzymes 0.5046820553351345 0.9773039640065048 0.32841869121229017 1.0 0.8045224329360506 10 O60568,P07237,O75718,Q32P28
Darpp 32 events -0.4642630151786975 -0.9763598872590669 0.32888615215642414 1.0 0.8045224329360506 10 Q08209,P17252,P62136,Q14738,Q00535,P17612
Metabolism of carbohydrates -0.24889217143300185 -0.9755300740332129 0.3292973913356183 1.0 0.8045224329360506 98 P14618,P52789,P06733,P00505,P17612,P78406,P18669,Q00796,Q7Z4W1,P36871,P07686,P40925,P35573,P04075,O95336,P29401,P40926,Q9UHD1,P14550,P15121,P37837,P60174,A6NDG6,O00754,P17174,Q04446,P09972,Q14376,P11413,P11498,Q16851,P53007,Q01813,P52209,O43252,P08237,P51570,P19367
Neuronal system 0.3615750645700787 0.9749500688839452 0.3295850282669459 1.0 0.8045224329360506 55 Q9BUF5,P51812,Q13885,P04350,P27361,O75955,O95197,P41440,Q14168,Q12959,Q9BVA1,P07196
Oncogene induced senescence -0.5005832972354027 -0.9741677391187078 0.32997326002028293 1.0 0.8045224329360506 8 P42771,P28482,Q9UPQ9
Amino acid transport across the plasma membrane 0.7761324041811509 0.9698280927061089 0.3321321873738854 1.0 0.807033135035942 3 P30825,P08195
Semaphorin interactions -0.3748416552301076 -0.9686622358095499 0.33271374041311796 1.0 0.807033135035942 21 P05556,Q13464,Q14195,Q16555,P61586,Q00535,O75116,Q9BPU6,P23528,Q9Y490,P63000
Interleukin 4 and interleukin 13 signaling 0.46335525091751284 0.9668798110113999 0.33360412031215936 1.0 0.807033135035942 14 P09601
Folding of actin by cct tric -0.49803722150591034 -0.9626286001563316 0.3357339395389003 1.0 0.807033135035942 8 P49368,P48643,Q99832,P50990,P17987,P50991,P40227
Calcineurin activates nfat -0.631746952988956 -0.959455824152333 0.3373291640158893 1.0 0.807033135035942 1 Q08209
Glucagon signaling in metabolic regulation -0.5994800011244394 -0.9578452630665069 0.33814079120173757 1.0 0.807033135035942 5 P17612,P62873
Vasopressin regulates renal water homeostasis via aquaporins -0.5994800011244394 -0.9578452630665069 0.33814079120173757 1.0 0.807033135035942 5 P17612,P62873
Neurotransmitter release cycle -0.5141538091164395 -0.9563441157164907 0.33889840860407205 1.0 0.807033135035942 7 P80404,P51649,O94925
Runx3 regulates p14 arf -0.778164924506435 -0.9557810113227179 0.3391828837441344 1.0 0.807033135035942 3 Q13951,P42771,P25440
Hdr through single strand annealing ssa -0.3799970857938731 -0.952920882949532 0.34063015843062905 1.0 0.807033135035942 19 P38398,P15927,P54132,O60921,P27694,P35244,Q92547,P40937,P35250,Q9H9A7,Q13315,P40938,P35249
P75 ntr receptor mediated signalling -0.3757441077892482 -0.9510627280131121 0.34157253385960096 1.0 0.807033135035942 20 Q12802,P52565,P61586,O14920,Q13547,P42574,Q7Z628
Degradation of the extracellular matrix -0.4779875362779586 -0.9508882052486107 0.3416611298557941 1.0 0.807033135035942 9 O15446,P17655,P20810,P42574,P04632
Apc cdc20 mediated degradation of nek2a 0.47461948375705026 0.9494572818813083 0.34238808861170744 1.0 0.807033135035942 12 Q9UJX2,Q96DE5,Q9UJX3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.47461948375705026 0.9494572818813083 0.34238808861170744 1.0 0.807033135035942 12 Q9UJX2,Q96DE5,Q9UJX3
O linked glycosylation of mucins 0.7704543667109602 0.9488274511036074 0.3427083777696227 1.0 0.807033135035942 3 O43505
Activation of atr in response to replication stress -0.36243463159444667 -0.9472010577243255 0.3435363365031705 1.0 0.807033135035942 23 O43913,Q99741,Q9HAW4,P15927,P24941,O60921,P27694,P35244,P40937,P35250,Q9UBD5,Q7L590,O75419,Q13415,P40938,P35249
Signaling by insulin receptor 0.44753761560292254 0.9471633244381461 0.34355556078624216 1.0 0.807033135035942 16 P31751,Q93050,Q9Y5K8,P27361,Q9Y487
Cyclin d associated events in g1 -0.43868664788505884 -0.9466742576386223 0.34380479177506484 1.0 0.807033135035942 11 P63151,P42771,P24941,Q13309
Raf activation -0.45790651243955627 -0.9462339072747622 0.34402929535941107 1.0 0.807033135035942 10 P62140,Q13555,Q02750
Fcgr3a mediated il10 synthesis 0.5164787072529565 0.9449648412211743 0.34467682597162597 1.0 0.807033135035942 9
Abc transporter disorders 0.36969972160214676 0.9446610749855221 0.34483193547300073 1.0 0.807033135035942 42 P60900,P28070,P28072,P49721,Q14997
Defective cftr causes cystic fibrosis 0.36969972160214676 0.9446610749855221 0.34483193547300073 1.0 0.807033135035942 42 P60900,P28070,P28072,P49721,Q14997
Sumoylation of chromatin organization proteins 0.38711202474006856 0.9443774399052892 0.34497680576676437 1.0 0.807033135035942 35 Q92621,Q8IXK0,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,P45973,Q8NFH4,Q9BTX1
Foxo mediated transcription of oxidative stress metabolic and neuronal genes -0.5958744915746709 -0.9429550938679963 0.3457038727085282 1.0 0.807033135035942 5 P04150,P04179,Q96ST3,Q92769,Q13547
Signalling to erks -0.45675261439769915 -0.9407906568639539 0.34681214981368313 1.0 0.807033135035942 10 Q16539,Q02750,P46109,P28482
Antigen presentation folding assembly and peptide loading of class i mhc 0.4590511220938483 0.9405503582431262 0.3469353315195258 1.0 0.807033135035942 14 Q9NZ08,Q6P179,P10321,P27824,P04439
Recognition of dna damage by pcna containing replication complex -0.3736635988440928 -0.9396216039266013 0.3474116906573408 1.0 0.807033135035942 20 Q9NZJ0,Q16531,P49005,P15927,P12004,P27694,P35251,P35244,P35250,P35249
Neddylation -0.2568626641025226 -0.9393469583218064 0.3475526363766015 1.0 0.807033135035942 76 O75147,P62333,Q7L5N1,P28066,O00487,P55036,Q16531,O00232,Q13309,P25786,Q93034,Q99460,Q15345,P61962,P61964,O75832,Q9NV06,O94888,Q15369,P25789,P43686,Q9NZJ0,Q15370,P35998,Q13200,P61081,O00233
Sensory perception -0.3303353614874605 -0.9393378883444804 0.3475572916298717 1.0 0.807033135035942 31 P30419,Q14651,P01130,P62873,O60551,P47755
Transcription coupled nucleotide excision repair tc ner -0.28416679457975363 -0.938349107516195 0.34806503075545914 1.0 0.807033135035942 48 Q16531,P49005,O15514,P15927,P12004,P27694,Q7L5N1,P62487,P35251,P35244,P35250,P55199,P35249,Q9UNP9
Advanced glycosylation endproduct receptor signaling -0.4731650597484359 -0.9289319924375665 0.3529243318588877 1.0 0.8139488435750951 9 P47755,P28482,P09429
Ubiquinol biosynthesis -0.7641907797981968 -0.9233852736469711 0.3558064632946123 1.0 0.8139488435750951 2 Q9Y2Z9
Ticam1 rip1 mediated ikk complex recruitment -0.6426168936750539 -0.9231946610793644 0.3559057706252373 1.0 0.8139488435750951 4 O14920,Q13404
Adp signalling through p2y purinoceptor 1 -0.7640058055151989 -0.9226273893753315 0.3562014171743222 1.0 0.8139488435750951 2 Q16539,P62873
Transcriptional regulation by tp53 -0.24953029061799986 -0.9223672783236823 0.3563370317205756 1.0 0.8139488435750951 131 Q99873,Q8TBX8,P19784,P30044,Q86YP4,Q9Y3B8,P27694,P62487,Q13547,P00390,P35250,Q9UPQ9,Q16881,Q9Y5B9,Q9H3P2,Q9NQ88,P20248,O95983,Q12873,P15927,P24941,O60921,P06744,O94776,P35244,P55199,P42771,Q13315,P40938,P35269,O15514,Q16539,P54132,P12004,P63104,Q9Y5B0,Q9H9A5,Q92547,Q15369,Q9H9A7,Q09028,P32119,Q15370,P11413,P38398,Q08945,P14635,P40937,O94925,P27348,O75175,P19387,O14965,Q14676,P35249
Hcmv late events 0.3824773882969769 0.9220344704489537 0.3565105957871493 1.0 0.8139488435750951 36 Q8N1F7,Q8NFH5,P57740,P61978,Q8NFH4,Q9BTX1,Q96FZ7
The phototransduction cascade -0.5055035141195057 -0.9178422180780036 0.35870147603859137 1.0 0.8139488435750951 7 P30419,P62873,O60551
Signaling by alk in cancer -0.31593535149119906 -0.917456195061044 0.3589036372813237 1.0 0.8139488435750951 35 P31939,P28482,Q9HC35,Q86WB0,Q63HN8,Q9NR09,P26641,P62753
Regulation of ras by gaps 0.37488349035026325 0.9163946749279346 0.35945992729235177 1.0 0.8139488435750951 39 P28072,P28070,P49721,P60900
Cs ds degradation -0.7617084375930363 -0.913222185071752 0.36112569827738117 1.0 0.8139488435750951 2 P07686
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3603288573602905 0.9129382936745936 0.3612749960291102 1.0 0.8139488435750951 44 P60900,P28070,P28072,P49721,Q14997
Trna processing in the mitochondrion -0.6399687522770243 -0.9126264685731487 0.36143902864203836 1.0 0.8139488435750951 4 Q9BQ52,Q99714
Hemostasis -0.24689380686692397 -0.9119412665567544 0.3617996366168037 1.0 0.8139488435750951 132 Q9UNF1,P28482,P21333,P05556,P07947,P37802,Q06124,P62873,Q96HP0,Q9BV23,Q12756,P23528,O75083,P47755,P04075
Miscellaneous transport and binding events 0.5207395405253857 0.9116246355731467 0.36196634925117555 1.0 0.8139488435750951 8
Asymmetric localization of pcp proteins 0.3766613448247533 0.9103200234210284 0.36265376166054963 1.0 0.8139488435750951 38 P28072,P28070,P49721,P60900
Degradation of dvl 0.3766613448247533 0.9103200234210284 0.36265376166054963 1.0 0.8139488435750951 38 P28072,P28070,P49721,P60900
Erks are inactivated -0.5036473395515422 -0.9096215322870498 0.3630221389740256 1.0 0.8139488435750951 7 P28482,P51452
Cd209 dc sign signaling -0.5389675120205533 -0.9090599381288267 0.36331848797269783 1.0 0.8139488435750951 6 P17612,Q16512,Q04206,P17252
G2 m dna damage checkpoint -0.30514359831073445 -0.9075736214650904 0.3641035362735745 1.0 0.8139488435750951 38 Q9Y3B8,P61981,P27694,P35250,Q9NWV8,P15927,O60921,P35244,Q12888,Q13315,P40938,O60934,O95714,P54132,P63104,Q92547,Q9H9A7,P38398,P14635,P40937,P27348,Q14676,P35249
Toll like receptor cascades -0.3248060775701307 -0.9073175149283392 0.36423891462130764 1.0 0.8139488435750951 31 Q8IV63,P28482,P09429,Q16539,P51452,Q06124,Q15418,O14920,Q02750,Q13404
Regulation of beta cell development 0.7590801411385116 0.9069901402409094 0.3644120112457143 1.0 0.8139488435750951 3 Q13573
Thrombin signalling through proteinase activated receptors pars -0.5865777655335097 -0.9047242991085882 0.36561146471237826 1.0 0.8139488435750951 5 P62873,P28482
Degradation of axin 0.3774744362919427 0.8969602016092593 0.36974015409987837 1.0 0.8139488435750951 37 P28072,P28070,P49721,P60900
Activation of bh3 only proteins -0.42818572518255715 -0.8956476441817194 0.37044098106742185 1.0 0.8139488435750951 11 Q9Y3B8,P63104,P27348,P63167,Q96FJ2
Basigin interactions 0.5275748305609008 0.8943657973889094 0.3711262060613074 1.0 0.8139488435750951 7 P35613,P53985
Neurofascin interactions 0.6033081834010484 0.8940458037462543 0.37129738471482043 1.0 0.8139488435750951 1
Hedgehog ligand biogenesis 0.3698476658690349 0.8935102129150947 0.3715840053680519 1.0 0.8139488435750951 40 P60900,P28070,P28072,P49721,Q14997
Pi3k akt signaling in cancer -0.46526813035759784 -0.8932645503025345 0.371715517254787 1.0 0.8139488435750951 9 Q96B36,Q06124
Signal regulatory protein family interactions -0.7613933493106209 -0.8931549991673388 0.3717741731581863 1.0 0.8139488435750951 3 Q06124
Cd163 mediating an anti inflammatory response -0.7567359485628251 -0.892915462841807 0.3719024457679132 1.0 0.8139488435750951 2 Q16539
Condensation of prometaphase chromosomes -0.4461030786617135 -0.8909571884073771 0.3729521381009506 1.0 0.8139488435750951 10 P19784,Q15003,Q9BPX3,P14635,O95067,O95347
Mrna decay by 3 to 5 exoribonuclease 0.438664332483392 0.890348861513241 0.37327859229044424 1.0 0.8139488435750951 16 Q969T7
Other interleukin signaling -0.5829607725745115 -0.8899191381858725 0.3735093067762314 1.0 0.8139488435750951 5 P42574,P40222,P29597,Q15833
Dcc mediated attractive signaling -0.6340400813243924 -0.8890306336820509 0.3739866164878194 1.0 0.8139488435750951 4 O00401,P16333,P63000,P60953
Thromboxane signalling through tp receptor -0.7599174157778793 -0.8876749950802022 0.37471560005121307 1.0 0.8139488435750951 3 P62873,Q13685
Parasite infection -0.32361749123744216 -0.8869809438531071 0.3750891601700752 1.0 0.8139488435750951 30 Q92558,Q92747,P16333,Q13459,P28482,P07947,P60953,P59998,O15145,O00401,P61158,P63000,Q9NZQ3,Q8IZP0,O15143,O00159
Death receptor signalling -0.32569298322745793 -0.8858189856733366 0.3757150773947653 1.0 0.8139488435750951 29 O14920,Q12802,P63244,Q96BN8
Peptide hormone metabolism 0.4428708532325983 0.8856079193822357 0.3758288426029166 1.0 0.8139488435750951 15 Q8NEW0
N glycan trimming in the er and calnexin calreticulin cycle 0.4498781474305807 0.8844829340405035 0.37643557098639646 1.0 0.8139488435750951 14 Q13724,Q9BUN8,Q9NYU2,P54727,Q13438
Dectin 2 family 0.6012768427161965 0.8838203036923875 0.3767932242183567 1.0 0.8139488435750951 1
Erythropoietin activates stat5 0.6012768427161965 0.8838203036923875 0.3767932242183567 1.0 0.8139488435750951 1
Cd22 mediated bcr regulation 0.6012768427161965 0.8838203036923875 0.3767932242183567 1.0 0.8139488435750951 1
Erythropoietin activates phosphoinositide 3 kinase pi3k 0.6012768427161965 0.8838203036923875 0.3767932242183567 1.0 0.8139488435750951 1
Traf6 mediated nf kb activation -0.47960140249638206 -0.8799882427545294 0.3788656788147846 1.0 0.8139488435750951 8 Q14258,O14920,P09429
Interleukin 1 processing -0.616947185142178 -0.8794560628244702 0.3791540460407885 1.0 0.8139488435750951 1 Q04206
Global genome nucleotide excision repair gg ner -0.2866038147938815 -0.8792989605172821 0.3792391993674309 1.0 0.8139488435750951 42 Q16531,P49005,Q9UGN5,P15927,P12004,Q9Y265,P27694,Q7L5N1,P35251,P25490,P35244,Q86WJ1,P35250,P35249
Rho gtpases activate rocks -0.44357574068711136 -0.8792447692637863 0.3792685750926932 1.0 0.8139488435750951 10 P23528,P62140,P61586
Diseases associated with glycosylation precursor biosynthesis -0.4621240279556096 -0.8791700688960894 0.3793090705911557 1.0 0.8139488435750951 9 Q14376,P51570,P34949,P36871
Switching of origins to a post replicative state 0.34940111906023247 0.8785591923488588 0.379640330076779 1.0 0.8139488435750951 62 Q96DE5,Q9UJX2,P60900,Q9Y619,P28070,P28072,Q14566,P49721,Q14997
Initiation of nuclear envelope ne reformation 0.42610181123858093 0.8777278450105431 0.38009142974318655 1.0 0.8139488435750951 18 Q86Y07,Q86XL3,P50402,P42167
Regulation of innate immune responses to cytosolic dna 0.6316309553595931 0.8773405754812288 0.3803016795562284 1.0 0.8139488435750951 4
Hiv life cycle -0.23012070774231425 -0.8729865936062551 0.38267038507793383 1.0 0.8176248019879903 84 P62826,P30419,Q15370,Q99816,O15514,Q08945,Q9NZZ3,P39748,P62487,Q9Y5B0,P18754,O60551,O43148,P55199,Q15369,P46060,Q9H3P2
Diseases of mitotic cell cycle 0.4547172542210533 0.8720674263572685 0.38317159501198983 1.0 0.8176248019879903 13 Q9UJX2,Q96DE5,Q9UJX3
Dual incision in tc ner -0.30458037238965424 -0.8696004596679323 0.38451878649552795 1.0 0.8190097524481461 36 Q16531,P49005,O15514,P15927,P12004,P27694,P62487,P35251,P35244,P35250,P35249,Q9UNP9
Nuclear events stimulated by alk signaling in cancer -0.41468087542222737 -0.8684306228176277 0.3851586367693427 1.0 0.8190097524481461 12 Q86WB0,P28482,Q9HC35,P62753
Bbsome mediated cargo targeting to cilium -0.4939269625661234 -0.8668325063075674 0.38603378859708815 1.0 0.8190097524481461 7 Q9NQ48,P49368,P50991,P48643
Ikba variant leads to eda id -0.7539892897153607 -0.865720377187119 0.38664352258783374 1.0 0.8190097524481461 3 O14920
Signaling by ntrks -0.3123064179433811 -0.8656055563790966 0.38670650749841995 1.0 0.8190097524481461 33 Q8IV63,P28482,Q16539,P51452,Q06124,P61586,Q15418,P46109,Q02750
Notch3 activation and transmission of signal to the nucleus -0.5760787534668066 -0.861866618270641 0.3887609204278901 1.0 0.8210250954136721 5 P00533,Q9Y6A5,O00308
Platelet homeostasis -0.41284192115920354 -0.859552474366511 0.39003578243530357 1.0 0.8210250954136721 12 P62873,Q06124
Signaling by kit in disease -0.5754596309055235 -0.8593508679909279 0.3901469676286933 1.0 0.8210250954136721 5 P42224,P07947
Glucagon like peptide 1 glp1 regulates insulin secretion -0.4918407986282872 -0.8577100599117952 0.39105258371436635 1.0 0.8210250954136721 7 P62873
Synthesis of prostaglandins pg and thromboxanes tx -0.6261271783448735 -0.8576873221419316 0.3910651424003633 1.0 0.8210250954136721 4 P16152
Intra golgi traffic 0.4383933777088124 0.8575705480305057 0.39112964376296144 1.0 0.8210250954136721 15 O95249,O00461,Q96JB2,Q13190,Q8TBA6
Signaling by ntrk2 trkb -0.5742870942366576 -0.8545900921090972 0.3927781145688205 1.0 0.8223564243600461 5 Q06124
Signaling by fgfr2 in disease -0.4037509630506328 -0.8541114350971963 0.39304324855906225 1.0 0.8223564243600461 13 P62487,O15514
Nr1h2 and nr1h3 mediated signaling 0.49864033587957474 0.8525244737231942 0.39392306142665534 1.0 0.8223564243600461 9 O60341
Glycogen breakdown glycogenolysis -0.525383985083822 -0.8517158187102558 0.3943718386746793 1.0 0.8223564243600461 6 P10253,P11216,Q6PCE3,P35573
Ca dependent events -0.4730804295286644 -0.8511940998033164 0.3946615398091553 1.0 0.8223564243600461 8 P17612,Q13555,P28482,Q05655
Sting mediated induction of host immune responses 0.5457281950134556 0.8497720416865483 0.3954518364553552 1.0 0.8227949500442068 6 P12956,P19474
Activated tak1 mediates p38 mapk activation -0.6232936392680472 -0.846508439928943 0.3972691675764788 1.0 0.8253659572342948 4 Q16539,Q16644,Q13404,Q15750
Pre notch expression and processing 0.4627159410902201 0.8439474357101411 0.398698779307185 1.0 0.8264064404562607 11 Q15363,Q13573
Mucopolysaccharidoses 0.741532473102288 0.843135241906598 0.39915281083051823 1.0 0.8264064404562607 3
Synthesis secretion and deacylation of ghrelin 0.7409441080031757 0.8410103326031375 0.4003421459452341 1.0 0.8264064404562607 3
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.7409441080031757 0.8410103326031375 0.4003421459452341 1.0 0.8264064404562607 3
Rrna modification in the mitochondrion 0.7297532656023196 0.840403993996129 0.4006819105242476 1.0 0.8264064404562607 2 Q9HC36
Generation of second messenger molecules -0.5223678600552604 -0.8390871603583593 0.4014204006148039 1.0 0.8267279368249735 6 P50552,P16333
Mitotic prophase 0.3455057121496515 0.8357138130273986 0.4033159225777967 1.0 0.8289466764789227 62 Q92621,P42167,Q08379,Q01105,Q86Y07,Q8N1F7,Q8NFH5,P57740,P50402,P27361,Q8NFH4,Q9BTX1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3493599929410127 0.8347603788141497 0.4038526382932248 1.0 0.8289466764789227 49 Q96DE5,P60900,P28070,P28072,P49721,Q9UJX2,Q14997
Depolymerisation of the nuclear lamina 0.47826356723834607 0.8340515892671975 0.4042519133798703 1.0 0.8289466764789227 10 P06493,P42167,P20700,P50402,P02545
Signalling to ras -0.6198657226112332 -0.8330182736172257 0.4048344233966832 1.0 0.8289466764789227 4 Q16539,Q16644,P11233
Cross presentation of soluble exogenous antigens endosomes 0.3679539904734023 0.8314270622391319 0.40573241633867063 1.0 0.8291207661168097 38 P28072,P28070,P49721,P60900
Dag and ip3 signaling 0.477210507167465 0.8283638607073497 0.40746446673760883 1.0 0.8291207661168097 10
G beta gamma signalling through cdc42 -0.7431948800704584 -0.8259904294557324 0.4088095208603133 1.0 0.8291207661168097 3 P62873
Signaling by fgfr2 iiia tm -0.4133216464272137 -0.8249449024511694 0.4094028721080283 1.0 0.8291207661168097 11 P62487,O15514
Fgfr2 mutant receptor activation -0.4133216464272137 -0.8249449024511694 0.4094028721080283 1.0 0.8291207661168097 11 P62487,O15514
Adherens junctions interactions 0.513081395348857 0.8247509185156504 0.4095130170285697 1.0 0.8291207661168097 7 P35221,P14923,P19022,O60716,P35222,Q9BY67
Signaling by moderate kinase activity braf mutants -0.3976610965567547 -0.8246257290821037 0.409584109489038 1.0 0.8291207661168097 13 Q13555,P28482,P30086,P41240,Q02750,P32121,Q9Y490
Diseases of signal transduction by growth factor receptors and second messengers -0.18756023993195403 -0.8240496621558945 0.40991134043225674 1.0 0.8291207661168097 150 Q9BZK7,Q7KZF4,Q9HC35,Q8IWJ2,P22681,P30086,Q06124,P62333,P62487,P28066,Q13547,O00487,Q7Z2W4,Q9P2E9,P26641,Q9Y490,P55036,Q9UBW7,Q9UNM6,O00232,P19387,P07947,P49336,P25786,Q63HN8,Q02750,Q99460,P62140,P62195,O75832,Q13555,P35269,O15514,P51665,Q13363,P42224,P41240,P55072,O00203,O95352,P25789,Q9UL46,P43686,P31939,Q96RT1,P28482,Q96B36,P06753,P35998,Q86WB0,O43252,Q13200,O14818,Q9NR09,O75376,O00233,P32121,P63000,P62753
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.39090154280472006 0.8235801862180594 0.41017813799436253 1.0 0.8291207661168097 26 P20700,O14979,Q13126,P52597,P22626
Degradation of gli1 by the proteasome 0.35676553090648566 0.8204729800691007 0.4119465264295794 1.0 0.8315108406878707 42 P28072,P28070,P49721,P60900
Regulation of ifng signaling -0.6159304860487054 -0.8175790705590174 0.4135975824193774 1.0 0.832703259256716 4 Q06124
Hedgehog on state 0.3476131843111762 0.8173806650224134 0.41371092161803014 1.0 0.832703259256716 45 P28072,P28070,P49721,P60900
Branched chain amino acid catabolism -0.378981649074002 -0.812680321853733 0.4164013663460473 1.0 0.8343326143429847 15 P30084,Q99714,Q96RQ3,Q6NVY1,P31937
Termination of translesion dna synthesis -0.3600491313574399 -0.8121326605211907 0.41671551414712726 1.0 0.8343326143429847 18 P49005,P15927,P12004,P27694,P35251,Q14258,P35244,P35250,Q14694,P35249
Ion homeostasis 0.44453381901329436 0.8115175166218055 0.4170685377357306 1.0 0.8343326143429847 13 P20020,P23634,O43865,P16615,P05023
Cardiac conduction 0.44453381901329436 0.8115175166218055 0.4170685377357306 1.0 0.8343326143429847 13 P20020,P23634,O43865,P16615,P05023
Fanconi anemia pathway -0.4810342082501937 -0.8108352414961874 0.41746029329353007 1.0 0.8343326143429847 7 P15927,P27694,P35244,Q16658
Trafficking and processing of endosomal tlr 0.7198838896952402 0.8025336960927351 0.42224430478648367 1.0 0.840404524019055 2 Q9H1C4
N glycan antennae elongation in the medial trans golgi 0.7195936139332335 0.8014266697110276 0.4228846806472317 1.0 0.840404524019055 2 Q16706
Reactions specific to the complex n glycan synthesis pathway 0.7195936139332335 0.8014266697110276 0.4228846806472317 1.0 0.840404524019055 2 Q16706
Interleukin 20 family signaling -0.5601724441702878 -0.7976915150076153 0.4250495289786693 1.0 0.840404524019055 5 P40763,P29597,Q06124,P42224
Muscle contraction 0.3786290065146267 0.7962868968998003 0.4258652997969774 1.0 0.840404524019055 29 P20020,P60660,P23634,P16615,Q9NYL9,O43865,P08670,P18206,P05023,P09493
Rhob gtpase cycle 0.3772523516925288 0.7940271454666105 0.42717962850470625 1.0 0.840404524019055 30 P02786
Tnfr2 non canonical nf kb pathway 0.34822296801799196 0.7929462193307897 0.42780915727608315 1.0 0.840404524019055 44 P28072,P28070,P49721,P60900
The activation of arylsulfatases 0.5827045850261221 0.7918419195394472 0.42845285625186347 1.0 0.840404524019055 1
Abc family proteins mediated transport 0.34419831304649695 0.7887006170634795 0.43028700718814794 1.0 0.840404524019055 54 P08183,P60900,P28070,P28072,P49721,Q14997
Defects in cobalamin b12 metabolism 0.725723562237848 0.7864477360503225 0.4316052265698591 1.0 0.840404524019055 3 Q99707
Biological oxidations 0.3445992532196074 0.786164744612818 0.43177097754882143 1.0 0.840404524019055 46 P27338,Q6QHF9,Q9NUJ1,O43169,Q16850,Q8TB61,P07099
Rho gtpases activate paks -0.40488881068444377 -0.7857517931927822 0.43201291359117255 1.0 0.840404524019055 11 P62140,P21333
Interleukin 2 signaling 0.581253627394085 0.784781073507097 0.4325819387716314 1.0 0.840404524019055 1
Beta oxidation of lauroyl coa to decanoyl coa coa 0.6075134072272124 0.7824933106949944 0.43392471507780606 1.0 0.840404524019055 4 Q16836
Pd 1 signaling -0.7291727140783401 -0.7817906820407412 0.4343375980160582 1.0 0.840404524019055 2 P41240,Q06124
Negative regulation of flt3 -0.7291727140783401 -0.7817906820407412 0.4343375980160582 1.0 0.840404524019055 2 P41240,P22681
Pentose phosphate pathway -0.45682077695655443 -0.780585875236305 0.4350461019171501 1.0 0.840404524019055 8 P49247,O95336,P11413,P29401,P37837,P52209
Dectin 1 mediated noncanonical nf kb signaling 0.34688571457104045 0.779679923442481 0.43557929896977665 1.0 0.840404524019055 44 P28072,P28070,P49721,P60900
Clec7a dectin 1 signaling 0.3435320355758525 0.7795377445933762 0.4356630124020531 1.0 0.840404524019055 53 P60900,O43865,P28070,P28072,P49721
Flt3 signaling in disease -0.4733209300619916 -0.77780418909724 0.43668445798312616 1.0 0.840404524019055 7 Q9UBW7,P22681,Q06124
Gp1b ix v activation signalling -0.7277213352684709 -0.7760162093806835 0.4377394151839764 1.0 0.840404524019055 2 P63104,P21333
Synthesis of pips at the early endosome membrane -0.5069175080784024 -0.7750789934523591 0.43829298356854807 1.0 0.840404524019055 6 Q13614,Q08AM6
Signaling by fgfr3 fusions in cancer 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Met activates pi3k akt signaling 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Shc1 events in erbb4 signaling 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Activated ntrk2 signals through ras 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Shc related events triggered by igf1r 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Shc mediated cascade fgfr3 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Activated ntrk3 signals through ras 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Sos mediated signalling 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Shc mediated cascade fgfr1 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Shc mediated cascade fgfr4 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Activated ntrk2 signals through pi3k 0.5786419036564183 0.7721211462586147 0.44004267889087934 1.0 0.840404524019055 1
Negative epigenetic regulation of rrna expression -0.31118458869486304 -0.7700742475470853 0.4412558510782212 1.0 0.8411330620453403 27 O15446,Q3B726,Q96ST3,Q96EB6,O43159,P26358,P62805,Q92769,P17480,Q13547,O95602,Q9GZS1,P19447,O00422
Fc epsilon receptor fceri signaling 0.3412209767611774 0.7694778704857965 0.44160967669047113 1.0 0.8411330620453403 58 P60900,O43865,P28070,P28072,P49721
Repression of wnt target genes -0.602682784340598 -0.7660104107130171 0.44367010768359805 1.0 0.8439247758753695 4 Q13547,Q13363
Abc transporters in lipid homeostasis 0.7192218350754924 0.7633974600622148 0.4452263942464585 1.0 0.8439703106301035 3 P56589,P28288
Pregnenolone biosynthesis 0.7191817426463265 0.7632558334965851 0.445310836561263 1.0 0.8439703106301035 3
Regulation of ifna signaling -0.5514565812998635 -0.7629749443154312 0.44547833873287357 1.0 0.8439703106301035 5 P18031,P29597,Q06124,P42224
Pre notch processing in golgi 0.7187868553338719 0.7618612355892193 0.4461428280978499 1.0 0.844102230761132 3 Q15363
Auf1 hnrnp d0 binds and destabilizes mrna 0.35039570355014277 0.7592425721390352 0.4477074637421805 1.0 0.8459346085887539 42 P28072,P28070,P49721,P60900
Oxidative stress induced senescence -0.3490629927097568 -0.7576356460372968 0.4486691343995164 1.0 0.8466243373841937 18 P28482,Q16539,O75530,Q9UPQ9,P42771,Q09028
Cd28 dependent vav1 pathway -0.5492104946512762 -0.754085672885041 0.45079777975639646 1.0 0.8495113538835678 5 Q16512,P63000,P60953
Telomere c strand synthesis initiation -0.5487905616417266 -0.7524264350521949 0.4517946542673421 1.0 0.8496378405576497 5 Q14181,P49642,P09884,P49643
Regulation of gene expression in early pancreatic precursor cells -0.5928612884503627 -0.751800739938695 0.4521708969731595 1.0 0.8496378405576497 1 O00330
Irak1 recruits ikk complex -0.7224452720962277 -0.750645887433291 0.4528657972185739 1.0 0.8496378405576497 3 O14920,Q13404
Ion channel transport -0.2996982369112492 -0.7479339803654678 0.4544999801003171 1.0 0.8496378405576497 29 Q9NTM9
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex -0.4316252794576564 -0.7461974892687472 0.45554812459375693 1.0 0.8496378405576497 9 Q9Y3B8,P61981,P63104,P14635,P27348
Defective intrinsic pathway for apoptosis -0.3588594020396112 -0.7446558008775325 0.45647982528328956 1.0 0.8496378405576497 16 O15446,P17655,P20810,P04632,P42771,P32119
Meiotic recombination -0.36475244600616125 -0.7442030652896301 0.4567536338818883 1.0 0.8496378405576497 15 O60934,P38398,P15927,P54132,P24941,P62805,P27694,P35244,Q13315,O43502
Ovarian tumor domain proteases -0.4308976873750828 -0.7431201339652515 0.45740895093608724 1.0 0.8496378405576497 9 Q14258,P55072,Q96FW1,P61586
Mapk targets nuclear events mediated by map kinases -0.41323199673535954 -0.7427427318599567 0.4576374532413654 1.0 0.8496378405576497 10 Q8IV63,P28482,Q16539,P51452,Q15418
Erk mapk targets -0.41323199673535954 -0.7427427318599567 0.4576374532413654 1.0 0.8496378405576497 10 Q8IV63,P28482,Q16539,P51452,Q15418
Sirt1 negatively regulates rrna expression -0.5462110284235199 -0.7422533618202144 0.45793384316555663 1.0 0.8496378405576497 5 O43159,Q96EB6
Trna processing in the nucleus -0.2592141278052888 -0.7417336075485836 0.45824875339804017 1.0 0.8496378405576497 42 P62826,O94992,Q92499,O43592,O95059,Q9Y224,Q9BQ52,O75818,Q99575,Q9Y3I0
Cellular response to chemical stress 0.3244637110000918 0.7408273804567437 0.45879811131603154 1.0 0.8496378405576497 78 P13073,P33527,P09601,P60900,P28070,P30519,P28072,P49721,P09669,P00403,Q14997
Circadian clock -0.3796845413572285 -0.7400864912941405 0.4592475149455373 1.0 0.8496378405576497 13 P04150,Q15648,Q9BZK7,Q96EB6,P62136,P62140
Polymerase switching on the c strand of the telomere -0.35751827906248673 -0.738306736436756 0.46032807384282015 1.0 0.8500578209168256 16 P49005,P12004,P35251,Q14181,P09884,P35250,Q8WVB6,P35249
Regulation of tp53 expression and degradation -0.3868313131015854 -0.7377397177142981 0.460672631631458 1.0 0.8500578209168256 12 P20248,P42771,Q13315
Degradation of beta catenin by the destruction complex 0.3396762680434696 0.7356570492573083 0.4619394344924195 1.0 0.8505653292224843 50 P28072,P28070,P49721,P60900
Unwinding of dna -0.4114224403937662 -0.7348778894209512 0.46241386526708195 1.0 0.8505653292224843 10 Q9Y248,Q9BRX5,O75419
2 ltr circle formation 0.5563896967776913 0.7340738439044049 0.46290373382980965 1.0 0.8505653292224843 5
Mtorc1 mediated signalling -0.4453798424351171 -0.7320703506719289 0.4641256295152527 1.0 0.8505653292224843 8 Q96B36,P62753
Factors involved in megakaryocyte development and platelet production 0.33931521933532643 0.7315553912160844 0.4644399841549056 1.0 0.8505653292224843 49 Q8IWA4,Q92845,Q9BUF5,O95140,Q13885,P04350,O60341,P45973,Q9BVA1,P68371
Shc1 events in erbb2 signaling -0.5936493187402064 -0.7312451177891265 0.4646294463318268 1.0 0.8505653292224843 4 P00533,Q05655,P17252
Irf3 mediated activation of type 1 ifn 0.5699361578641959 0.7304035507309572 0.46514354860933604 1.0 0.8505653292224843 1
Oas antiviral response -0.5929762678913569 -0.728668998077504 0.46620416108067 1.0 0.851407599193656 4 Q6L8Q7,P21333,Q9Y6K5
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.4743271441468888 0.7275539891946801 0.4668866546467012 1.0 0.85155805005613 9 P07196,P51812,Q12959,Q14168
Ikk complex recruitment mediated by rip1 -0.5420225726133525 -0.7258072431238024 0.46795694599277926 1.0 0.851578625760568 5 O14920,Q13404
Postmitotic nuclear pore complex npc reformation 0.38772469541309285 0.7247828003323359 0.46858528906964114 1.0 0.851578625760568 23 Q8N1F7,Q8NFH5,P57740,Q8NFH4,Q9BTX1
Translesion synthesis by y family dna polymerases bypasses lesions on dna template -0.32814181430124384 -0.7245986075761169 0.4686983134031033 1.0 0.851578625760568 21 P49005,P15927,P12004,P27694,P35251,Q14258,P55072,P35244,P40937,P35250,Q14694,P40938,P35249
Signaling by egfr -0.3542158880532427 -0.7227997638928321 0.46980291241917294 1.0 0.852494031614842 16 Q99961,P22681,P60953,Q13685,Q06124,P41240,P00533,P49023,Q9Y6I3,P42566
Inhibition of replication initiation of damaged dna by rb1 e2f1 -0.4925776591626807 -0.7168426301456704 0.4734712042316289 1.0 0.8545104269035557 6 Q14181,P49642,P09884,P49643
Fatty acyl coa biosynthesis 0.4017764406116211 0.7157238396363468 0.4741618874395046 1.0 0.8545104269035557 18 Q9UMR5,P49327,Q9NZ01,P50897
Prolactin receptor signaling -0.7126329258130055 -0.715557566217878 0.4742645832550374 1.0 0.8545104269035557 3 Q06124
Telomere extension by telomerase -0.38171470891923664 -0.7147185925880142 0.47478294672323496 1.0 0.8545104269035557 12 Q9NX24,P20248,O00743,P24941,Q9Y265,O60832,Q5H9R7
Gaba synthesis release reuptake and degradation -0.7117184338166103 -0.7123069963562673 0.47627469256441946 1.0 0.8545104269035557 3 P80404,P51649
Rora activates gene expression -0.5886246721017715 -0.712062900698383 0.47642582630358365 1.0 0.8545104269035557 4 Q9BZK7,Q15648
Elevation of cytosolic ca2 levels -0.5850261172373625 -0.7111231375604369 0.4770079332452135 1.0 0.8545104269035557 1 Q14571
Long term potentiation 0.5503884554637378 0.7095517031472843 0.47798217851715386 1.0 0.8545104269035557 5 Q12959,P07196
Unblocking of nmda receptors glutamate binding and activation 0.5503884554637378 0.7095517031472843 0.47798217851715386 1.0 0.8545104269035557 5 Q12959,P07196
Ras activation upon ca2 influx through nmda receptor 0.5503884554637378 0.7095517031472843 0.47798217851715386 1.0 0.8545104269035557 5 Q12959,P07196
Negative regulation of nmda receptor mediated neuronal transmission 0.5503884554637378 0.7095517031472843 0.47798217851715386 1.0 0.8545104269035557 5 Q12959,P07196
Protein folding 0.36008445399027833 0.7092966027331362 0.47814043619550617 1.0 0.8545104269035557 35 Q9BUF5,Q15813,P78371,Q13885,P04350,P04062,Q9BVA1
Ptk6 regulates rho gtpases ras gtpase and map kinases -0.5368424743259552 -0.7055965631673172 0.4804390621690424 1.0 0.8567905772249008 5 P49023,P63000,P61586
Translesion synthesis by polk -0.40424725223039576 -0.7040445367755325 0.48140503846796223 1.0 0.8567905772249008 10 P15927,P12004,P35251,P27694,P35244,P35250,P35249
Rhot1 gtpase cycle -0.5835751596053255 -0.7036431750178932 0.48165501666859756 1.0 0.8567905772249008 1 Q8IXI2
Chromatin modifying enzymes -0.15550736075510832 -0.7033599041368273 0.4818314874034326 1.0 0.8567905772249008 79 Q99873,Q9BZK7,Q9BQA1,Q86YP4,O75530,Q13547,Q9Y2K7,Q96EB1,O95983,Q12873,O96019,Q15291,Q9Y4A5,P15880,Q6IA86,Q15014,O60678,O94776,O95163,Q96ES7,O75529,P61964,P51610,Q12824,Q09028,Q68CP9,O00422,Q6NYC1,Q7LBC6,Q9Y265,O75376
Trafficking of myristoylated proteins to the cilium 0.700928510226811 0.6994787799423446 0.48425286984602556 1.0 0.8596004014895146 3
Detoxification of reactive oxygen species -0.40303343713204465 -0.6988861233840536 0.48462320027597716 1.0 0.8596004014895146 10 P30044,P30041,P00390,Q16881,P32119
Stabilization of p53 0.3487395405567959 0.6966911865550586 0.4859960755867152 1.0 0.8609593398970649 40 P28072,P28070,P49721,P60900
Orc1 removal from chromatin 0.3351051497072602 0.6911845364254864 0.4894495803569512 1.0 0.8652412774596799 53 P60900,Q9Y619,P28070,P28072,P49721,Q14997
Hdr through mmej alt nhej -0.4354574595390635 -0.6908931982145531 0.4896326608880359 1.0 0.8652412774596799 8 O60934,P49916,Q9UGN5,P39748,P09874
Estrogen biosynthesis 0.5606500290191586 0.6867832098248822 0.4922193518692517 1.0 0.8665891451633394 1
Rhoc gtpase cycle 0.351897690323221 0.6859894820164206 0.492719741030164 1.0 0.8665891451633394 38 P02786,P27105,P41440
Tryptophan catabolism 0.6883850548134722 0.6849861995865494 0.49335262947151426 1.0 0.8665891451633394 2
Rab regulation of trafficking -0.24906729270308317 -0.684105890112916 0.49390830275764785 1.0 0.8665891451633394 41 P51153,Q9ULP9,Q9UL33,P61006,Q9UJY4,P50395,Q9Y2L5,P62330,Q7Z392,P60520
Regulation of plk1 activity at g2 m transition 0.3516734334905347 0.6839615910418115 0.4939994198671065 1.0 0.8665891451633394 38 P41208,O43805,P07437,P04350,O95684,O75935,O94927,P61163,P68371
Prc2 methylates histones and dna -0.450826225130449 -0.683866242244929 0.4940596324433697 1.0 0.8665891451633394 7 P26358,Q09028,O75530
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.36002043160439734 0.6825525794534734 0.4948896074584963 1.0 0.8669732752884027 33 Q9BUF5,Q13885,P04350,Q9UJW0,O75935,Q9BVA1,P61163,P68371
C type lectin receptors clrs 0.33288284769372456 0.6796703007021737 0.496713245225477 1.0 0.8690950616213956 58 P60900,O43865,P28070,P28072,P49721
Assembly of the hiv virion -0.7013699708967465 -0.6757718802913248 0.4991854906463311 1.0 0.8716712270174952 3 Q99816,O60551
Transmission across chemical synapses 0.33637217740912295 0.6754118005984264 0.49941417023623935 1.0 0.8716712270174952 44 Q9BUF5,P51812,Q13885,P04350,Q14168,Q12959,Q9BVA1,P07196
Runx1 regulates transcription of genes involved in differentiation of myeloid cells -0.7010135925103691 -0.6714329690447163 0.5019447479686456 1.0 0.873863759857419 2 Q13951
Miro gtpase cycle 0.5782054055362306 0.670275507527191 0.5026821774398327 1.0 0.873863759857419 4 Q8IWA4
Hdr through homologous recombination hrr -0.28045468470263507 -0.6694267660706946 0.5032232822373885 1.0 0.873863759857419 30 P49005,O43542,P38398,P15927,P12004,P27694,P35251,P35244,Q92547,P35250,Q13315,P35249
Nade modulates death signalling -0.7002621186730441 -0.6685409758145985 0.5037883349993644 1.0 0.873863759857419 2 P42574
Activation of caspases through apoptosome mediated cleavage -0.7002621186730441 -0.6685409758145985 0.5037883349993644 1.0 0.873863759857419 2 P42574
Transport to the golgi and subsequent modification 0.3117259879691302 0.6676369878705738 0.5043653413130558 1.0 0.873863759857419 84 P49755,Q9Y3B3,P24390,Q08379,P04350,Q96JB2,O95249,O43731,P61163,P68371,Q96PC5,Q9BUF5,Q13561,Q13885,Q8IUR0,Q9UJW0,O75935,Q14789,Q9BVA1,Q15363,Q92734,Q9Y296,Q13190,O15027
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.6899433680687067 0.6618333748293269 0.5080780142862993 1.0 0.8779566291291516 3
Insulin receptor signalling cascade -0.478654138405933 -0.6615717415976524 0.5082457227525221 1.0 0.8779566291291516 6 P28482,Q06124
Activation of the pre replicative complex -0.3017623610456482 -0.6602177416286467 0.5091141085692026 1.0 0.8779566291291516 24 O43913,Q99741,P15927,P27694,P35244,Q14181,P09884,Q9UBD5,Q7L590,Q13415,O75419
Signaling by notch1 -0.3692136344017789 -0.6599934141912694 0.5092580556471378 1.0 0.8779566291291516 12 Q9BZK7,P49336,Q13547,O75376,P32121
Translesion synthesis by polh -0.3615183093701074 -0.6591055419549666 0.5098279971485082 1.0 0.8779566291291516 13 P15927,P12004,P27694,Q8TAT6,P55072,P35251,P35244,P40937,P35250,P40938,P35249
Irf3 mediated induction of type i ifn 0.5375573821359927 0.6576819288981083 0.510742536748654 1.0 0.8779566291291516 5
Er to golgi anterograde transport 0.31443585042119715 0.6571902162770684 0.5110586156875823 1.0 0.8779566291291516 81 P49755,Q9Y3B3,P24390,Q08379,P04350,Q96JB2,O95249,O43731,P61163,P68371,Q96PC5,Q9BUF5,Q13561,Q13885,Q8IUR0,Q9UJW0,O75935,Q14789,Q9BVA1,Q15363,Q92734,Q9Y296,Q13190
Signaling by nuclear receptors -0.17080341415281602 -0.654543039283305 0.5127620080177624 1.0 0.8798177622457133 67 Q9BZK7,O15514,P25490,P62487,P62873
Scavenging by class a receptors 0.6871666167666408 0.6524135166849473 0.5141344469938782 1.0 0.8811072225655957 3 Q5KU26
Gap filling dna repair synthesis and ligation in gg ner -0.3198240747883585 -0.6513194226424083 0.5148403131316257 1.0 0.8811921970749887 19 P49005,P15927,P12004,P27694,P35251,P35244,P35250,P35249
Downstream signaling events of b cell receptor bcr 0.331156104080405 0.6500287678677443 0.5156736393332126 1.0 0.8811921970749887 46 P28072,P28070,P49721,P60900
Interaction between l1 and ankyrins -0.5719923547073859 -0.6494508336055752 0.5160470160460293 1.0 0.8811921970749887 4 Q12955,O15020
Methylation -0.40777286178170946 -0.648111338772311 0.5169129407751667 1.0 0.8816099314422614 9 P51580,P23526,Q9NZL9,P31153
Formation of incision complex in gg ner -0.3509498663631617 -0.6464458081408341 0.5179906821962761 1.0 0.8819101844048477 14 Q16531,Q9UGN5,P15927,P27694,Q86WJ1,P35244
Transport of fatty acids -0.5722576900754364 -0.6459187284211282 0.5183319899884729 1.0 0.8819101844048477 1 Q6P1M0
Dna damage telomere stress induced senescence -0.3236262053066187 -0.6401067392960864 0.5221032079215515 1.0 0.8872345919733065 18 P20248,P16403,P10412,P07305,Q13315
Sars cov 1 infection 0.4207950584653517 0.6386804420025005 0.5230308385050302 1.0 0.8872345919733065 12 Q13724,Q10472
Interleukin 12 signaling 0.3581318510720825 0.6382098194053378 0.5233371060476797 1.0 0.8872345919733065 30 P20700,O14979,Q13126,P52597,P22626
Nuclear pore complex npc disassembly 0.35783114294947826 0.6357706874354092 0.5249258955937992 1.0 0.8878429116527814 30 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.4729819484628596 0.6357378700375471 0.5249472888489666 1.0 0.8878429116527814 7 Q16836,P40939,P49748
Uptake and actions of bacterial toxins 0.47205452501931566 0.6314529118591643 0.5277444287234427 1.0 0.8910081929679757 7
Regulated necrosis 0.37980235845932747 0.6309478504373318 0.5280746231755233 1.0 0.8910081929679757 21 P41440
Tight junction interactions -0.5687753917585474 -0.6283933257091784 0.5297463082569465 1.0 0.8913686971870586 1 Q9Y624
Rna polymerase i transcription initiation -0.2986171046528809 -0.62793933255871 0.5300436833508746 1.0 0.8913686971870586 23 O15446,O95983,Q12873,Q86YP4,Q3B726,Q92769,P17480,Q13547,O94776,O95602,Q09028,Q9GZS1
Activation of kainate receptors upon glutamate binding -0.6871180177942086 -0.6262632054521946 0.5311423160588853 1.0 0.8913686971870586 3 Q15334,P62873
Tp53 regulates transcription of genes involved in cytochrome c release -0.6890663928285373 -0.6258259368707423 0.5314291175618404 1.0 0.8913686971870586 2 Q13315
Tp53 regulates transcription of caspase activators and caspases -0.6890663928285373 -0.6258259368707423 0.5314291175618404 1.0 0.8913686971870586 2 Q13315
Regulation of fzd by ubiquitination 0.5467208357516028 0.6232421028774716 0.5331254379819161 1.0 0.8931582012943791 1
Esr mediated signaling -0.2046295274539827 -0.6215199094291388 0.5342575990458238 1.0 0.8939994493467264 49 P28482,O15514,P25490,P62487,P62873,P53041
Loss of mecp2 binding ability to the ncor smrt complex -0.6851850872671198 -0.6196263583176232 0.535503809125454 1.0 0.895029334686713 3 Q9BZK7,O75376
Pcp ce pathway 0.32801006974164987 0.6152780016298222 0.5383711427963083 1.0 0.8979097767110077 50 P28072,P28070,P49721,P60900
Stat3 nuclear events downstream of alk signaling -0.5620098751088892 -0.6125985114015997 0.5401418427679814 1.0 0.8979097767110077 4 P40763,Q13547,Q96ST3,Q92769
Enos activation -0.5619787262527614 -0.6124844489488187 0.540217283794427 1.0 0.8979097767110077 4 O75608,O95865
Costimulation by the cd28 family -0.3349837247620925 -0.611550332377648 0.5408353077503611 1.0 0.8979097767110077 15 Q06124,P07947
Glycogen storage diseases -0.6826364692218647 -0.6109054347037418 0.5412621867213716 1.0 0.8979097767110077 3 P10253,Q04446,P13807
Rap1 signalling -0.5613067963538978 -0.6100253985942902 0.5418449829217766 1.0 0.8979097767110077 4 P17612,P63104,P17252
Fceri mediated nf kb activation 0.3272396692064095 0.6091404953623284 0.5424313178867446 1.0 0.8979097767110077 47 P28072,P28070,P49721,P60900
Diseases associated with n glycosylation of proteins 0.49059143855824383 0.6080743172323602 0.5431381850936421 1.0 0.8979097767110077 6 Q13724
Formation of the beta catenin tcf transactivating complex -0.35666915108214603 -0.6074747529033774 0.5435358926564011 1.0 0.8979097767110077 12 Q15291,Q9Y4A5,Q6P1J9,Q9Y265,Q13547
Mhc class ii antigen presentation 0.3265900347787911 0.6047981345169332 0.5453131333084065 1.0 0.8979097767110077 55 Q9BUF5,Q92845,P10619,Q13561,Q13885,P04350,Q9UJW0,O75935,Q9BVA1,P61163,P68371
Wnt mediated activation of dvl -0.6834703681101286 -0.6047503031362715 0.5453449189492723 1.0 0.8979097767110077 2 P19784
Rhod gtpase cycle 0.35180257526996955 0.6032279754779721 0.54635703947819 1.0 0.8979097767110077 32 Q9Y6M7,P42167,P20700,Q8TAA9,Q86Y07,P50402,O15173,Q86YQ8
Mrna capping -0.32680552580141975 -0.6018563491857541 0.5472697624955207 1.0 0.8979097767110077 16 P62487,O15514
Fgfr2 alternative splicing 0.38441679797630834 0.6014470409179518 0.5475422750937247 1.0 0.8979097767110077 18 P52597,P30876,P31943,P31483
Synthesis of pips at the plasma membrane -0.3551130879800371 -0.6011416779455517 0.5477456258464573 1.0 0.8979097767110077 12 Q8NCE2,Q8TBX8,Q96PE3,Q01968,Q13614,Q96T51,Q9Y217
Wnt ligand biogenesis and trafficking -0.5587243127666309 -0.6006005058179383 0.5481061009880239 1.0 0.8979097767110077 4 O60493
Smad2 smad3 smad4 heterotrimer regulates transcription -0.5090797251868279 -0.6000587208996646 0.548467101692621 1.0 0.8979097767110077 5 Q13547,P49336,P28482
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.5222075479560869 0.5967804055894779 0.5506540017421861 1.0 0.8979097767110077 5 Q5KU26,P10321
G2 phase -0.6812772133526591 -0.5965433349272641 0.5508123131773597 1.0 0.8979097767110077 2 P20248,P24941
G1 s dna damage checkpoints 0.3334300856732013 0.5964597617179257 0.5508681271701534 1.0 0.8979097767110077 42 P28072,P28070,P49721,P60900
Integrin signaling -0.5074067961627267 -0.5938672910577374 0.5526008776154601 1.0 0.8979097767110077 5 P41240,P18031,Q9Y490
Platelet aggregation plug formation -0.5074067961627267 -0.5938672910577374 0.5526008776154601 1.0 0.8979097767110077 5 P41240,P18031,Q9Y490
Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members -0.5615206035983621 -0.5922708572900677 0.5536692275719697 1.0 0.8979097767110077 1 P40763
Transcriptional regulation of pluripotent stem cells -0.5615206035983621 -0.5922708572900677 0.5536692275719697 1.0 0.8979097767110077 1 P40763
Pou5f1 oct4 sox2 nanog activate genes related to proliferation -0.5615206035983621 -0.5922708572900677 0.5536692275719697 1.0 0.8979097767110077 1 P40763
Carnitine metabolism -0.46063979550665934 -0.5922556786171475 0.5536793901494939 1.0 0.8979097767110077 6 O00763,Q13085
Sensory processing of sound -0.3006436699558119 -0.5860953074432748 0.5578114695432255 1.0 0.9024406164290175 20 P47755,Q14651
Tbc rabgaps -0.3287263920875865 -0.5858115706912225 0.5580021472888943 1.0 0.9024406164290175 15 P61006,Q9ULP9,Q9UJY4,P62330,P60520
Acyl chain remodeling of cl 0.6595171145158899 0.5826944951610556 0.5600989796566436 1.0 0.9024406164290175 2
Cellular senescence -0.1812032284319382 -0.582411535084856 0.5602895136176407 1.0 0.9024406164290175 48 P20248,P28482,Q16539,Q9UPQ9,P42771,O75530,Q15418,P16403,P10412,P07305,Q09028,Q13315
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.665906779378439 0.5817009216727262 0.5607681506097071 1.0 0.9024406164290175 3
Regulation of gene expression in beta cells 0.659226838753916 0.5816968089954915 0.5607709212988412 1.0 0.9024406164290175 2
Ethanol oxidation -0.6739547875973018 -0.5814631038572633 0.5609283781170737 1.0 0.9024406164290175 3 P11766,P30837
Integration of provirus 0.48397954493416445 0.580081750819498 0.561859489630713 1.0 0.9024406164290175 6
Synthesis of substrates in n glycan biosythesis -0.3091557327933288 -0.5795813495081957 0.5621969731664915 1.0 0.9024406164290175 18 O14772,Q16222,Q96EK6,O95394,Q8NFW8,Q06210,P34949,Q9UJ70,O60547,Q96IJ6
Rho gtpases activate ktn1 -0.42405199637365176 -0.5777861700001747 0.5634084936062151 1.0 0.9026483658178632 7 P61586,P63000,P60953
Activation of nima kinases nek9 nek6 nek7 -0.5029576638864569 -0.5775046071083834 0.5635986272830351 1.0 0.9026483658178632 5 O95067,Q8TD19,P14635
Signaling by alk -0.501743172574089 -0.5730647270982671 0.5666008689292832 1.0 0.9061059397684387 5 Q96ST3,P40763,Q92769,Q13547,P19174
Hsf1 dependent transactivation -0.33254335054064704 -0.570407922377585 0.5684010574709406 1.0 0.9061059397684387 14 Q96B36,Q92598
Interleukin 2 family signaling -0.5502016131405825 -0.5698022663176464 0.568811818248304 1.0 0.9061059397684387 4 P42224,P40763
Release of apoptotic factors from the mitochondria 0.6557001184483612 0.5696285120349316 0.568929685966928 1.0 0.9061059397684387 2
Rho gtpases activate wasps and waves -0.29250104046938624 -0.5695982122979164 0.5689502412499499 1.0 0.9061059397684387 21 Q92558,P16333,Q92747,P28482,P60953,P59998,O15145,O00401,P61158,P63000,Q9NZQ3,Q8IZP0,O15143
Pyrimidine salvage -0.5492322776273973 -0.5663302337157425 0.5711693114731564 1.0 0.9070535869373625 4 P04183
Triglyceride catabolism -0.420926308413975 -0.5658837501772467 0.5714728087416119 1.0 0.9070535869373625 7 P62140,P62136
Mapk6 mapk4 signaling 0.3231952364295325 0.5656257147952017 0.5716482433114634 1.0 0.9070535869373625 51 P28072,P28070,P49721,P60900
Nuclear signaling by erbb4 -0.5488173438691915 -0.5648459772076863 0.5721785313278729 1.0 0.9070535869373625 4 P61201,O75376
L1cam interactions 0.3276347574549249 0.5640187422972862 0.5727413769526968 1.0 0.9070535869373625 43 P07942,Q9BUF5,P51812,Q13885,P04350,Q12959,Q9BVA1
Response of eif2ak1 hri to heme deficiency -0.5483071623285529 -0.5630226480917603 0.5734194619664923 1.0 0.9071150685958221 4 P41091
Rna polymerase ii transcription termination -0.14210061782877187 -0.5606296774175836 0.575050015779198 1.0 0.9073026753030352 48 Q12996,P84103,Q10570,P33240,P62304,O00148,Q9P2I0,Q09161,Q01081,Q05519,O94992,Q96FV9,O60508,Q08170,Q8IYB3,O43809,Q5KU26,Q13242,Q86V81,Q92620,Q9UKF6,Q16629,P62318,Q86U42,P82979,Q15287,Q9BY77,Q13247,Q05048,Q13769,Q9Y5S9,P51003,Q86W42,O75152,P38919,Q92797,Q8NI27,P26368,Q9BZI7,Q96J01,Q8N684,P52298,Q07955,Q9Y3Y2,Q13838,Q9C0J8,Q6UN15,Q13243
Mitotic metaphase and anaphase 0.3365778221269841 0.5601126296903143 0.575402616357791 1.0 0.9073026753030352 144 P49721,Q86XL3,Q96EA4,Q96DE5,P60900,P04350,Q8NFH5,P57740,P28072,Q9UJX2,Q8NFH4,Q9BTX1,Q14997,Q9UJX3,P42167,Q9BUF5,P28070,Q13885,Q8N1F7,P50402,Q9BVA1,Q96FZ7,Q92621,P20618,P20700,Q86Y07
Positive epigenetic regulation of rrna expression -0.24542085456481996 -0.5599719962248945 0.5754985389869565 1.0 0.9073026753030352 32 P35659,Q9UIG0,O15446,O95983,Q12873,Q86YP4,Q9BQG0,Q3B726,Q92769,Q13547,O94776,O95602,Q09028,Q9GZS1,O00159
G1 s specific transcription 0.3958029784319588 0.5586758146130876 0.5763829881028937 1.0 0.9073026753030352 14 P00374
Polymerase switching -0.32920353017977216 -0.5573352961061112 0.5772983644229686 1.0 0.9073026753030352 14 P49005,P12004,P35251,Q14181,P09884,P35250,P35249
Diseases of glycosylation -0.2930799048901229 -0.5565062861005471 0.5778647983660383 1.0 0.9073026753030352 20 Q14376,P51570,P34949,P07686
Regulation of runx2 expression and activity 0.32432363468231956 0.5562882394287969 0.5780138255630329 1.0 0.9073026753030352 44 P28072,P28070,P49721,P60900
Rna polymerase ii transcribes snrna genes -0.2501727779571197 -0.5545646198616657 0.579192494499164 1.0 0.9081482317064239 30 Q96P16,P35269,O15514,Q5TA45,Q8N201,P62487,Q68E01,P55199,P19387
Visual phototransduction -0.3492440684018588 -0.5497340946437153 0.5825017681275417 1.0 0.9123289282262491 11 P01130,P30419,P62873,O60551
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein -0.27809081306388933 -0.5474043751291325 0.5841009501568699 1.0 0.913105039325209 23 Q96EK6,O60547,P34949
Runx2 regulates osteoblast differentiation -0.5438316703157923 -0.5471064128992562 0.5843056267511826 1.0 0.913105039325209 4 Q13951,P28482,P07947
Sema4d mediated inhibition of cell attachment and migration -0.6676342525398894 -0.5462010383654037 0.5849277524641403 1.0 0.913105039325209 2 P63000,P61586
Grb2 sos provides linkage to mapk signaling for integrins -0.6669691430318117 -0.543779573223034 0.5865931669728077 1.0 0.9146757510108782 2 Q9Y490
Rmts methylate histone arginines -0.2853966859563704 -0.5428644688218397 0.5872231213325652 1.0 0.9146757510108782 21 Q99873,Q9BQA1,Q12824,P15880,O96019,O14744,P62805,Q92925,O60678,Q96GM5,Q92922,Q68CP9,P61964
Crmps in sema3a signaling -0.44568889438208326 -0.5369138489285676 0.5913271243698033 1.0 0.9186879681129185 6 Q9BPU6,Q14195,Q16555
Regulation of bach1 activity -0.5404938138198012 -0.5353301248363961 0.5924215987987305 1.0 0.9186879681129185 4 Q13309,O14867
Hdms demethylate histones 0.43574800372657113 0.5340269449697359 0.5933228920132563 1.0 0.9186879681129185 9
Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis -0.6641509433962035 -0.5335547605583767 0.5936496147511168 1.0 0.9186879681129185 2 P28702,O75376
Intracellular signaling by second messengers 0.2971394572903626 0.5332298338726807 0.5938744919672665 1.0 0.9186879681129185 89 P60900,O43865,P28070,O60341,P28072,P49721,P46934
Apoptotic execution phase -0.22780770220697885 -0.5323569815569585 0.5944787737336521 1.0 0.9186879681129185 34 O00273,P09429,Q9UJU6,Q14974,Q05655,P42574,P16403,P10412,P07305
Signaling by notch1 pest domain mutants in cancer -0.37706726139239466 -0.5319528303581096 0.5947586655849049 1.0 0.9186879681129185 9 Q13547,Q9BZK7,P49336,O75376
Mrna splicing minor pathway -0.22303650759054058 -0.531635713410561 0.5949783246622777 1.0 0.9186879681129185 35 Q96DI7,O15514,P62487,P62318,P55769
Nuclear import of rev protein 0.3438638448795108 0.5231187049460961 0.6008916495804015 1.0 0.9258858915883948 30 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Oncogenic mapk signaling -0.24614440502221768 -0.5230420867725032 0.6009449655764001 1.0 0.9258858915883948 28 Q7KZF4,Q13555,P28482,P30086,P32121,P41240,O43252,Q7Z2W4,Q02750,O00203,O95352,P62140,Q9Y490
Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 -0.6609579100144914 -0.522040475319774 0.6016421495708504 1.0 0.9259546748818186 2 Q13404,Q15750
Notch1 intracellular domain regulates transcription -0.3724985718304309 -0.5158171306067195 0.6059821368382792 1.0 0.9316236751609082 9 Q13547,Q9BZK7,P49336,O75376
Ns1 mediated effects on host pathways 0.34097741077058064 0.5138594013581587 0.6073502938193807 1.0 0.9324703427013713 32 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Bmal1 clock npas2 activates circadian gene expression 0.5348457463428907 0.512952735811327 0.6079843828440321 1.0 0.9324703427013713 4
Nef and signal transduction -0.6572910905898723 -0.5089124145458876 0.6108136177009311 1.0 0.9324703427013713 2 P63000
Pyroptosis -0.3878404559975177 -0.5079947293200022 0.6114570395317054 1.0 0.9324703427013713 8 P42574,Q8WUX9,Q16611,P09429
Mecp2 regulates neuronal receptors and channels -0.437111267429614 -0.5061756186315907 0.6127333693209156 1.0 0.9324703427013713 6 P18031,Q13547,Q96ST3,Q92769
Cyclin a b1 b2 associated events during g2 m transition -0.33007886474715925 -0.5053902832018901 0.6132847422249144 1.0 0.9324703427013713 12 P63151,P20248,P24941,Q9Y570,P14635,O95067
Regulation of commissural axon pathfinding by slit and robo 0.5191526407428987 0.5052815440454845 0.6133611037070088 1.0 0.9324703427013713 1
Dna double strand break response -0.2702319097021315 -0.5052135797443098 0.6134088333992178 1.0 0.9324703427013713 22 Q13315,Q9UIG0,O60934,P38398,O95714,Q99728,Q04323,P62805,O96028,Q12888,Q14676,Q8N2W9,P53041,Q9NWV8
Transport and synthesis of paps 0.6362221564870479 0.5048421672518765 0.6136696963954837 1.0 0.9324703427013713 2
Gdp fucose biosynthesis -0.650696864111522 -0.5047995696135149 0.6136996181384884 1.0 0.9324703427013713 3 O14772,Q13630,O60547
Pten regulation 0.3130757663275311 0.5033813163188042 0.614696205014285 1.0 0.9324703427013713 67 P60900,P28070,O60341,P28072,P49721,P46934
Heme biosynthesis -0.48044157085235045 -0.49720639658753124 0.6190435111247536 1.0 0.9324703427013713 5 P06132,P08397
Formation of senescence associated heterochromatin foci sahf -0.3670882841214755 -0.49713386886281896 0.6190946522245555 1.0 0.9324703427013713 9 P10412,P07305,P16403
Interleukin 1 signaling 0.3164137697123405 0.4969650827153233 0.6192136746673171 1.0 0.9324703427013713 49 P28072,P28070,P49721,P60900
Perk regulates gene expression -0.29916794499752936 -0.4965190737652745 0.6195282335591867 1.0 0.9324703427013713 16 P08243,Q9NQT5,P41091,Q9NPD3,Q9NQT4,P05198,P20042,Q9Y3B2,Q06265,Q9Y2L1,Q5RKV6,Q13868
Cell surface interactions at the vascular wall 0.3681600850930448 0.496231540574722 0.6197310604216699 1.0 0.9324703427013713 18 P53985
Ksrp khsrp binds and destabilizes mrna -0.3125988363866415 -0.49596960708764 0.6199158543606522 1.0 0.9324703427013713 14 Q16539,Q9NPD3,P63104,Q9NQT4,Q9Y3B2,Q06265,Q9Y2L1,Q5RKV6,Q13868
Estrogen dependent gene expression -0.20353787618491964 -0.4949080366411975 0.6206650374830047 1.0 0.9324703427013713 35 P62487,O15514,P25490
Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway -0.5412071967498432 -0.4942677685274487 0.6211170848886693 1.0 0.9324703427013713 1 Q12933
G protein beta gamma signalling -0.4794758144191759 -0.49386368251466567 0.6214024547020327 1.0 0.9324703427013713 5 P62873,P61586
Rhov gtpase cycle -0.266501002357632 -0.49328420721112 0.6218117856785335 1.0 0.9324703427013713 22 Q7Z6J0,P16333,Q96KM6
Regulation of lipid metabolism by pparalpha 0.34748046930450766 0.4930850749174946 0.6219524761862227 1.0 0.9324703427013713 26 P37268,P23786
Sumoylation of transcription cofactors -0.3265293524613757 -0.49282087124103946 0.6221391621068082 1.0 0.9324703427013713 12 Q15424,Q9UIS9,Q96ST3,Q13263,Q13363,Q9HC52,Q8N2W9,Q99497
Tfap2 ap 2 family regulates transcription of growth factors and their receptors -0.6463414634146571 -0.49083512762530607 0.623543062830906 1.0 0.9324703427013713 3 Q6PL18,P00533,P25490
Inla mediated entry of listeria monocytogenes into host cells 0.6316400580551649 0.49008930344078383 0.6240707068933187 1.0 0.9324703427013713 2 O60716
Noncanonical activation of notch3 0.6304789550072527 0.48638202203072145 0.6266963346542069 1.0 0.9324703427013713 2 Q92542
Irs mediated signalling -0.5257701204785369 -0.4844065633571309 0.6280973613536005 1.0 0.9324703427013713 4 Q06124
Coenzyme a biosynthesis -0.6443150962788055 -0.48438331749246133 0.628113855683357 1.0 0.9324703427013713 3 Q96CD2
Acetylcholine neurotransmitter release cycle 0.5139291932675653 0.48425509388104304 0.6282048413335859 1.0 0.9324703427013713 1
Norepinephrine neurotransmitter release cycle 0.5139291932675653 0.48425509388104304 0.6282048413335859 1.0 0.9324703427013713 1
Serotonin neurotransmitter release cycle 0.5139291932675653 0.48425509388104304 0.6282048413335859 1.0 0.9324703427013713 1
Hyaluronan uptake and degradation -0.5257200115058421 -0.4842362468727264 0.6282182153787952 1.0 0.9324703427013713 4 Q9UHD1,P07686
Hyaluronan metabolism -0.525720011505842 -0.48423624687272576 0.6282182153787956 1.0 0.9324703427013713 4 Q9UHD1,P07686
Budding and maturation of hiv virion -0.33074278057405593 -0.4825171619340583 0.629438609883108 1.0 0.9333055249990911 11 Q9NZZ3,Q8WUX9,O75351,Q99816
Cell cell junction organization 0.43210235533586655 0.4815700772357363 0.6301113870164836 1.0 0.9333278269064618 8 P35221,P55196,P14923,P19022,O60716,P35222,Q9BY67
Negative regulation of notch4 signaling 0.32540032702229843 0.480576083817599 0.6308178166131897 1.0 0.9333998767196205 40 P28072,P28070,P49721
Opioid signalling -0.27062931432793036 -0.47859566182133106 0.6322263051479198 1.0 0.9343979150768138 20 P28482,P62873,P62136
Deubiquitination 0.30119224487561064 0.4777764847091613 0.6328092997807033 1.0 0.9343979150768138 100 P21796,P45880,P60900,P28070,Q15388,P28072,P49721
Separation of sister chromatids 0.3081272342787988 0.4747949358836049 0.6349331428745157 1.0 0.9363374899113767 110 Q96DE5,Q9UJX3,P20618,Q9BUF5,P60900,P28070,Q13885,P04350,P57740,P28072,P49721,Q9UJX2,Q8NFH4,Q9BVA1,Q96EA4,Q14997
Receptor mediated mitophagy -0.6403393863452328 -0.47181034718983494 0.6370621646426038 1.0 0.9363374899113767 3 P19784
Glucuronidation 0.6309316354444299 0.4716634035316009 0.6371670628097499 1.0 0.9363374899113767 3
Displacement of dna glycosylase by apex1 -0.6399880978264303 -0.4707049351360272 0.637851459664246 1.0 0.9363374899113767 3 P27695
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism -0.4726792773967442 -0.47059495345954017 0.6379300121285358 1.0 0.9363374899113767 5 P17612,Q14738,P17252
Dap12 interactions 0.48852062969124044 0.46864364088900473 0.6393243778623612 1.0 0.9363374899113767 5
Signaling by notch3 -0.3760998582266788 -0.4674726453604373 0.6401617586707102 1.0 0.9363374899113767 8 Q15398,P42224,P00533,Q9Y6A5,O00308
Mapk3 erk1 activation -0.42579225362064455 -0.4668562939248124 0.6406026968256426 1.0 0.9363374899113767 6 Q02750,Q06124
Dna damage recognition in gg ner -0.271018077326649 -0.46670964971578993 0.6407076248656014 1.0 0.9363374899113767 19 Q7L5N1,Q16531,Q9Y265,P25490
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 -0.47118847961887905 -0.4655523516740287 0.6415359558727172 1.0 0.9363374899113767 5 P62873
Incretin synthesis secretion and inactivation -0.47118847961887905 -0.4655523516740287 0.6415359558727172 1.0 0.9363374899113767 5 P62873
Transcriptional activity of smad2 smad3 smad4 heterotrimer -0.32489893154626814 -0.46270840507288585 0.6435733928101088 1.0 0.9363374899113767 11 P28482,P49336,Q13547,Q93008,O75376
Regulation of tp53 activity through acetylation -0.31019455255062 -0.46229289704407217 0.6438712925995631 1.0 0.9363374899113767 13 Q8TBX8,O95983,Q12873,Q86YP4,Q8WYH8,Q92769,Q13547,O94776,Q09028
Protein repair -0.5342426001160653 -0.46186773241777385 0.6441761749551216 1.0 0.9363374899113767 1 P22061
Signaling by type 1 insulin like growth factor 1 receptor igf1r -0.46990779376531905 -0.46123849288200014 0.644627507763043 1.0 0.9363374899113767 5 Q06124
G protein mediated events 0.38410814335432897 0.4611645276964477 0.6446805691637878 1.0 0.9363374899113767 13
Nephrin family interactions -0.3558197663137665 -0.4597700631055353 0.645681273465941 1.0 0.9368320317465952 9 O00401,P16333
Endosomal sorting complex required for transport escrt -0.3149771791337668 -0.45379773977279125 0.6499744105666798 1.0 0.942097741158446 12 O75351,Q9NZZ3,Q8WUX9,Q9BRG1,Q99816
Signaling by fgfr in disease -0.24725270363475596 -0.45220467770862943 0.6511215386574019 1.0 0.9427974115865849 23 P62487,O15514
Regulation of tp53 activity through methylation -0.4184056778184219 -0.4420144985665604 0.6584787143449777 1.0 0.9473452151767429 6 O14744,Q13315,Q9H9B1,Q96KQ7
Arms mediated activation 0.6156748911465848 0.4402617085824619 0.6597475706228315 1.0 0.9473452151767429 2 P31946
Cargo concentration in the er 0.37522483445463406 0.43934448913396246 0.6604119424617891 1.0 0.9473452151767429 14 Q15363,Q96PC5,P49755
Interleukin 12 family signaling 0.33084574791743687 0.43872159543288686 0.6608632773040881 1.0 0.9473452151767429 33 P20700,O14979,Q13126,P52597,P22626
Uch proteinases 0.3103893769457939 0.4358071213852554 0.662976676565252 1.0 0.9473452151767429 49 P28072,P28070,P49721,P60900
Extra nuclear estrogen signaling -0.30183178247960984 -0.43563248999840887 0.6631033940606905 1.0 0.9473452151767429 13 P62873,P28482
Hiv transcription initiation -0.2862935957366139 -0.4352691465537604 0.6633670772786828 1.0 0.9473452151767429 15 P62487,O15514
P75ntr negatively regulates cell cycle via sc1 -0.6359941944847426 -0.43481517390578106 0.6636965899301925 1.0 0.9473452151767429 2 Q13547,Q92769
Regulation of runx3 expression and activity 0.3237848458694402 0.4340111424731429 0.6642803497280814 1.0 0.9473452151767429 38 P28072,P28070,P49721
Gap junction degradation 0.4787914003486302 0.4333456810249389 0.6647636561454788 1.0 0.9473452151767429 5 P09496,Q96CW1,P50570,Q9UM54
Atf6 atf6 alpha activates chaperones 0.6129326685204515 0.43196061549196346 0.6657700380876235 1.0 0.9473452151767429 2
Atf6 atf6 alpha activates chaperone genes 0.6129326685204515 0.43196061549196346 0.6657700380876235 1.0 0.9473452151767429 2
Pi3k events in erbb2 signaling -0.6350290379396003 -0.4315496657180649 0.6660687481444516 1.0 0.9473452151767429 2 P00533
Grb2 events in erbb2 signaling -0.6350290379396003 -0.4315496657180649 0.6660687481444516 1.0 0.9473452151767429 2 P00533
Shc1 events in egfr signaling -0.6350290379396003 -0.4315496657180649 0.6660687481444516 1.0 0.9473452151767429 2 P00533
Downregulation of erbb2 signaling -0.3648684500425951 -0.4307171599931804 0.6666740399788138 1.0 0.9473452151767429 8 Q9UNE7,Q96RT1,Q93034
Myogenesis 0.42696711830961753 0.4303723172973301 0.6669248291463858 1.0 0.9473452151767429 7
Tp53 regulates transcription of genes involved in g1 cell cycle arrest -0.6267729925046236 -0.42979719254481324 0.6673431752822456 1.0 0.9473452151767429 3 P20248,P24941
Mrna splicing 0.33009353094380217 0.42813526915892125 0.6685526403120039 1.0 0.9473452151767429 150 P51991,P33240,P62304,P62312,Q9UBB9,P35637,Q15637,Q5KU26,P52597,O75533,P52272,P61978,O75937,O95400,Q13242,P38159,P30876,Q86V81,P62995,Q16629,P52756,P22626,Q13151,Q6P2Q9,O75494,O43290,Q9BUJ2,P31943,P55795,Q12874,Q9BZJ0,Q9Y5S9,Q15427,Q9H2H8,Q14103,Q8N684,P52298,O43390,Q07955,Q8WUA2,Q8IWX8,P07910,Q9P013,Q6UN15,Q92733,Q13573
Nuclear events kinase and transcription factor activation -0.2993084531617813 -0.42792103293315464 0.6687086134596079 1.0 0.9473452151767429 13 P28482,Q8IV63,Q16539,P51452,Q15418
Rab gefs exchange gtp for gdp on rabs -0.15494126484309978 -0.42690865576136705 0.6694458607465179 1.0 0.9473452151767429 32 P51153,P61006,Q9UL33,P50395,Q9Y2L5,Q7Z392
Triglyceride metabolism -0.3635901913969169 -0.4266649201261201 0.6696234049017713 1.0 0.9473452151767429 8 P62140,P62136
Apc c mediated degradation of cell cycle proteins 0.30925640369565743 0.42642789048128876 0.6697960819271773 1.0 0.9473452151767429 58 Q96DE5,P60900,P28070,P28072,P49721,Q9UJX2,Q14997
Constitutive signaling by aberrant pi3k in cancer -0.4591728993748214 -0.42575671908340823 0.6702851275810076 1.0 0.9473452151767429 5 Q06124
Keratan sulfate keratin metabolism 0.47595943588633616 0.4232362124405484 0.6721229285580026 1.0 0.9482975837411323 5
Vxpx cargo targeting to cilium -0.3280426629491498 -0.4221538428627348 0.6729127295732429 1.0 0.9482975837411323 10 P61006,O00471,O60645
Scf skp2 mediated degradation of p27 p21 0.3150671235644915 0.42208383785236 0.6729638244026217 1.0 0.9482975837411323 42 P28072,P28070,P49721
Transport of vitamins nucleosides and related molecules 0.4447658290181416 0.4207042154226902 0.6739710825958722 1.0 0.9487747680590701 6 Q8TB61,P12235
Association of tric cct with target proteins during biosynthesis -0.2543027400905575 -0.4196768449174707 0.6747215426918651 1.0 0.9488898603367261 19 P49368,P48643,Q99832,P50990,P17987,P50991,Q15477,P40227,O00567,P61962
P38mapk events -0.6231126596980443 -0.41870842257901436 0.6754292394365606 1.0 0.9489446443173065 3 Q16539,Q16644,P11233
Flt3 signaling -0.456248733053951 -0.4163088894100006 0.6771839885929594 1.0 0.9499036547375003 5 P41240,P22681,Q06124
Interferon gamma signaling -0.2874526053984798 -0.41559583166410446 0.677705777364563 1.0 0.9499036547375003 14 Q13555,O15344,Q06124,P42224,Q14258,Q05655,P29372
Netrin 1 signaling -0.30161702255270245 -0.41244399468508136 0.6800140224001421 1.0 0.9499036547375003 12 P16333,P60953,Q16539,Q06124,O00401,P63000
Beta oxidation of very long chain fatty acids 0.5047481420886621 0.4120875334526822 0.68027526581633 1.0 0.9499036547375003 4
Amyloid fiber formation -0.3764219149997549 -0.40993696782720196 0.6818521862323415 1.0 0.9499036547375003 7 Q9UJY4,Q93008
Signaling by braf and raf1 fusions -0.2212687543633825 -0.4088860260751888 0.6826233044329395 1.0 0.9499036547375003 24 Q7KZF4,Q13555,P28482,P30086,P41240,O43252,Q7Z2W4,Q02750,O00203,O95352,P32121,Q9Y490
Meiosis -0.19546484813731874 -0.4072353950265368 0.6838351075739075 1.0 0.9499036547375003 27 O60934,P38398,P15927,O60216,P54132,P24941,P62805,P27694,Q14683,Q9BTC0,P35244,Q13315,O43502
Reproduction -0.19546484813731874 -0.4072353950265368 0.6838351075739075 1.0 0.9499036547375003 27 O60934,P38398,P15927,O60216,P54132,P24941,P62805,P27694,Q14683,Q9BTC0,P35244,Q13315,O43502
Rrna processing in the mitochondrion -0.40728967282431805 -0.40593555596958514 0.6847899520238676 1.0 0.9499036547375003 6 Q9BQ52,Q99714
Beta catenin phosphorylation cascade 0.42093023255813095 0.4047918843543672 0.6856304947704726 1.0 0.9499036547375003 7 P30154,P30153,P48729,Q13362,P25054,P35222
Disassembly of the destruction complex and recruitment of axin to the membrane 0.42093023255813095 0.4047918843543672 0.6856304947704726 1.0 0.9499036547375003 7 P30154,P30153,P48729,Q13362,P25054,P35222
Signaling by ctnnb1 phospho site mutants 0.42093023255813095 0.4047918843543672 0.6856304947704726 1.0 0.9499036547375003 7 P30154,P30153,P48729,Q13362,P25054,P35222
Rna polymerase i transcription -0.1787535050648022 -0.4028909281455563 0.6870284653627352 1.0 0.9499036547375003 28 O15446,O95983,Q12873,Q86YP4,Q3B726,Q92769,P17480,Q13547,O94776,O95602,Q09028,Q9GZS1
Notch hlh transcription pathway -0.40623683882655287 -0.40260328537788437 0.6872400923749173 1.0 0.9499036547375003 6 Q9BZK7,Q04721,Q92769,Q13547,O75376
Synthesis of ip2 ip and ins in the cytosol -0.6175958188153488 -0.40220307336228683 0.6875345805730568 1.0 0.9499036547375003 3 Q96PE3,Q9NPH2,Q01968
Rhobtb3 atpase cycle -0.5006307488631134 -0.4017823677170452 0.6878441997177545 1.0 0.9499036547375003 4 Q15345
Rho gtpases activate nadph oxidases -0.37368329913676795 -0.40127368702386346 0.6882186341690759 1.0 0.9499036547375003 7 P28482,P17252,Q16539,Q05655,P63000
Prevention of phagosomal lysosomal fusion 0.5012803159342163 0.4010010231903968 0.6884193705908592 1.0 0.9499036547375003 4 O14964
Trp channels -0.5206035983749169 -0.4004423070375268 0.6888307686574262 1.0 0.9499036547375003 1 Q13546
Negative regulation of the pi3k akt network -0.28939653610993354 -0.3991617349751622 0.6897740361868525 1.0 0.9502809294651882 13 P28482,Q06124
G alpha i signalling events -0.20593318798176044 -0.3970379167906949 0.6913395001665417 1.0 0.9515138222466756 25 P28482,P62873,P62136
B wich complex positively regulates rrna expression -0.2334389006146811 -0.3959855054674948 0.6921157210695099 1.0 0.9516591164705761 21 P35659,O15446,Q9UIG0,Q3B726,Q9BQG0,P62805,Q9H9Y6,Q9NY93,O95602,Q9GZS1,O00159
Synthesis of ketone bodies -0.6144811927828582 -0.3929976567352034 0.6943212120928135 1.0 0.953479556786128 3 P24752,P35914
Apoptotic factor mediated response -0.35239559868447423 -0.39237175428177806 0.6947835530069459 1.0 0.953479556786128 8 P42574,P42771,P28482
Chl1 interactions -0.6133942441902258 -0.3898046848790048 0.696680979242676 1.0 0.9551597193674949 3 P05556
Ketone body metabolism -0.49617763697084216 -0.38777929828401325 0.6981793666819487 1.0 0.9559371246626497 4 P55809,P24752,P35914
Scavenging by class f receptors -0.49599755294035086 -0.38721729467591276 0.6985953476216826 1.0 0.9559371246626497 4 Q92598
Deposition of new cenpa containing nucleosomes at the centromere -0.3309580593101765 -0.3853531803017981 0.699975765765039 1.0 0.9569032867250389 9 Q09028,Q9Y265
Dissolution of fibrin clot -0.6206700747909641 -0.38399690994646035 0.700980737768248 1.0 0.9573548285785792 2 P35237
Caspase mediated cleavage of cytoskeletal proteins 0.409545412120659 0.3802581581737608 0.7037537917377359 1.0 0.9588040345313634 8
Signaling by notch4 0.3084824276376213 0.37985477309401544 0.7040532211850592 1.0 0.9588040345313634 43 P28072,P28070,P49721
Atf4 activates genes in response to endoplasmic reticulum stress -0.2821974284499835 -0.37983361951300576 0.704068924581875 1.0 0.9588040345313634 13 P08243,Q9NPD3,Q9NQT4,Q9Y3B2,Q06265,Q9Y2L1,Q5RKV6,Q13868
Reduction of cytosolic ca levels 0.4941732960761437 0.3786595604404795 0.7049406869966053 1.0 0.9590707908419778 4 P23634,P16615
Il 6 type cytokine receptor ligand interactions -0.6187357140362872 -0.37774384458326216 0.7056208935251671 1.0 0.9590766742454139 2 P29597
Nucleotide salvage -0.3121940168804786 -0.3768129131095536 0.7063126436494571 1.0 0.9590982213766313 10 P00492,P04183,Q01433
Activated ntrk2 signals through cdk5 -0.6177068214803917 -0.374433155617618 0.7080820793828295 1.0 0.9597552983148616 2 Q00535,P63000
Piwi interacting rna pirna biogenesis 0.3767692513860157 0.3743428470810226 0.7081492581646653 1.0 0.9597552983148616 11 Q8N2A8,P30876
Retrograde transport at the trans golgi network -0.23350108782836215 -0.373402869653929 0.7088486240314147 1.0 0.9597864479967342 19 P83436,Q8IWJ2,P82094,P46459,Q99747,Q5VIR6,P20645,P54920
Mtor signalling -0.27642554915795453 -0.3653003546972764 0.7148872136651696 1.0 0.9670388100534247 13 Q96B36,Q9Y376,P62753
Synthesis of very long chain fatty acyl coas 0.39988735077439136 0.36357953949548677 0.7161720077187463 1.0 0.9670388100534247 9 Q9NZ01
Pi metabolism -0.21420782198880256 -0.363476020050871 0.7162493230205422 1.0 0.9670388100534247 21 Q9UBF8,Q08AM6,Q13614,Q9Y217,P48739
Syndecan interactions -0.43878626066485743 -0.3619641190035513 0.7173788438193682 1.0 0.9670597457354432 5 P05556
Apoptotic cleavage of cellular proteins 0.33645080647496994 0.3616309338679586 0.7176278451440603 1.0 0.9670597457354432 23 Q07157,P49354,P35611,P20700,P08670,P25054,P02545,Q16625,P51572
Clec7a inflammasome pathway -0.6029415418388953 -0.3596301696254 0.7191237189679514 1.0 0.9681561263904392 3 Q9UDY8
E2f enabled inhibition of pre replication complex formation 0.42734508152963235 0.3544737843139038 0.7229838473271473 1.0 0.9714682266896951 6
Ephrin signaling -0.43614381613846864 -0.35406534526597266 0.7232899124419245 1.0 0.9714682266896951 5 Q16512,P63000
Traf3 dependent irf activation pathway -0.6110268594850532 -0.3532029452948274 0.7239362999829282 1.0 0.9714682266896951 2 Q14258
Constitutive signaling by overexpressed erbb2 -0.48454714288883843 -0.35218986246608447 0.7246958791101752 1.0 0.9714682266896951 4 Q96RT1
Constitutive signaling by akt1 e17k in cancer -0.4843463406435838 -0.3515883168926516 0.7251470282479549 1.0 0.9714682266896951 4 Q96B36
Rac1 gtpase cycle 0.30222630512137727 0.34923717687150935 0.7269112580539838 1.0 0.9714682266896951 54 P02786,P42167,O96013,Q86Y07,P50402,Q9UQB8
Neurexins and neuroligins -0.3167438184140588 -0.3481574589026402 0.727721934356776 1.0 0.9714682266896951 9 Q15334,Q96HC4,P11171,Q9UJU6
Tcr signaling 0.30200093035109904 0.34768751435932505 0.7280748744396803 1.0 0.9714682266896951 52 P28072,P28070,P49721,P60900
Beta oxidation of octanoyl coa to hexanoyl coa -0.4335846560338317 -0.34650051949052096 0.7289665938665226 1.0 0.9714682266896951 5 P30084,P11310
Beta oxidation of decanoyl coa to octanoyl coa coa -0.4335846560338317 -0.34650051949052096 0.7289665938665226 1.0 0.9714682266896951 5 P30084,P11310
Chaperone mediated autophagy -0.3876343885062201 -0.3463035100113375 0.7291146310250354 1.0 0.9714682266896951 6 Q99497
Nonhomologous end joining nhej -0.1984995098083616 -0.3446839505436176 0.7303319851712613 1.0 0.9717945771189648 21 Q13315,O60934,P38398,Q9NUW8,O95714,O95551,P62805,Q5UIP0,P13010,Q12888,Q14676,P78527,Q8N2W9,Q9NWV8
Signaling by hippo -0.3868008132179961 -0.34389933679735274 0.7309219906427162 1.0 0.9717945771189648 6 Q13043,P42574
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.45267417615671085 0.34322469463225025 0.7314294281808846 1.0 0.9717945771189648 5
Diseases of immune system -0.43196163104199814 -0.3417467714670501 0.7325414704021451 1.0 0.9717945771189648 5 O14920,P09429
Tgf beta receptor signaling in emt epithelial to mesenchymal transition -0.607255931080039 -0.34142482416969405 0.7327837896527782 1.0 0.9717945771189648 2 P61586
Hdacs deacetylate histones -0.2479923554095574 -0.34031830808994523 0.733616831253229 1.0 0.9719909276828496 15 Q9BZK7,O95983,Q12873,Q13547,O94776,O75376,Q09028,O00422
Nicotinamide salvaging 0.5795926287018354 0.3376322885655094 0.7356403068429862 1.0 0.9722980502832689 2
Aquaporin mediated transport -0.38408160229137983 -0.33613011649168023 0.7367727486602953 1.0 0.9722980502832689 6 P62873
Interleukin receptor shc signaling 0.5788098693759022 0.33557237194805284 0.7371933610235519 1.0 0.9722980502832689 2 P23458
Role of lat2 ntal lab on calcium mobilization 0.5788098693759021 0.33557237194805195 0.7371933610235526 1.0 0.9722980502832689 2 P07948
Rho gtpase cycle 0.3365139507479472 0.3354646169035077 0.7372746315044378 1.0 0.9722980502832689 175 P02786,Q9UNZ2,P51648,O75976,P30519,Q13505,O95202,Q86XL3,P38159,Q9P0I2,P62995,Q16718,P27105,O75955,Q07065,Q9Y6M7,P42167,P78371,P08670,Q15904,Q15058,P50402,Q9Y512,O43396,O15173,Q86YQ8,Q8N684,P61604,P20700,O96013,Q8TAA9,Q86Y07,P07910,Q96HY6,P41440,Q13190,Q9UIW2,Q9UQB8
Epha mediated growth cone collapse -0.27846347574460895 -0.33258492322259686 0.7394476256227742 1.0 0.9742582922550758 11 P61586,P07947
Map2k and mapk activation -0.26111526877531704 -0.3309327895333414 0.7406952536548168 1.0 0.9749968134844017 13 P28482,P30086,P41240,Q02750,P32121,Q9Y490
Heme signaling 0.39785136087812367 0.32990370669005625 0.7414727226299065 1.0 0.9751156565447983 8
Cyclin a cdk2 associated events at s phase entry 0.2986114625972493 0.3275864679262846 0.743224354884962 1.0 0.9761585258704994 45 P28072,P28070,P49721
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3593827334831425 0.32667369171115435 0.7439147004650768 1.0 0.9761585258704994 13
E3 ubiquitin ligases ubiquitinate target proteins -0.23979255476437827 -0.32525516441813 0.7449879611503674 1.0 0.9761585258704994 15 Q9GZS3,P68036,P12004,Q6P1J9,Q14527,P55072
Transcriptional regulation by runx3 0.30462720984411845 0.3246562241360152 0.7454412694329571 1.0 0.9761585258704994 42 P28072,P28070,P49721
Egfr transactivation by gastrin -0.590236973154495 -0.3243074036482745 0.7457053150413118 1.0 0.9761585258704994 3 P00533,P17252
Glyoxylate metabolism and glycine degradation 0.3583640006608611 0.32130637894075653 0.7479782228078382 1.0 0.9781682940570916 13
Inlb mediated entry of listeria monocytogenes into host cell -0.3784711210918903 -0.3204604773200741 0.7486192863608185 1.0 0.9781682940570916 6 Q99961,P22681
Phospholipase c mediated cascade fgfr4 -0.5011607661056202 -0.318082369648126 0.7504224566553457 1.0 0.9787219356561908 1 P19174
Phospholipase c mediated cascade fgfr2 -0.5011607661056202 -0.318082369648126 0.7504224566553457 1.0 0.9787219356561908 1 P19174
Trna modification in the mitochondrion -0.34374695398011323 -0.3147821938362353 0.7529270322275181 1.0 0.9810867389631296 7 Q99714,Q9Y606
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.39860022909834847 0.3137836479838324 0.7536853646228656 1.0 0.9811738829356388 7
Suppression of apoptosis -0.46991499993363584 -0.30956315496890363 0.7568931788275266 1.0 0.9825676552089945 4 Q63HN8,P28482
Hdl assembly -0.5965166908563025 -0.30873156214835457 0.7575257327685976 1.0 0.9825676552089945 2 P17612,P17252
Acetylcholine regulates insulin secretion -0.5965166908563025 -0.30873156214835457 0.7575257327685976 1.0 0.9825676552089945 2 P29966,P17252
Pka mediated phosphorylation of key metabolic factors -0.5965166908563025 -0.30873156214835457 0.7575257327685976 1.0 0.9825676552089945 2 P17612,P17252
Negative regulation of met activity -0.3199944201000288 -0.3060496053314068 0.7595668770526462 1.0 0.9843154324545251 8 Q99961,P22681
Fceri mediated mapk activation -0.2976618768678127 -0.30470553896928143 0.7605904306236915 1.0 0.9845377091996991 9 P28482
G beta gamma signalling through pi3kgamma -0.5816962959210437 -0.30144096670979925 0.7630782592492977 1.0 0.9845377091996991 3 P62873,P61586
Trafficking of ampa receptors -0.2620856137924746 -0.2989475076862658 0.7649800977193997 1.0 0.9845377091996991 11 Q15334
Chondroitin sulfate dermatan sulfate metabolism -0.465943110845606 -0.29842866006315727 0.7653760174912452 1.0 0.9845377091996991 4 P07686
Disinhibition of snare formation -0.5927431059506428 -0.29755204780588596 0.7660450778398817 1.0 0.9845377091996991 2 O00186,P17252
Pka mediated phosphorylation of creb -0.4650014522218809 -0.29581713539709464 0.7673697362027034 1.0 0.9845377091996991 4 P17612,P13861,P10644,P17252
Creb1 phosphorylation through the activation of adenylate cyclase -0.4650014522218809 -0.29581713539709464 0.7673697362027034 1.0 0.9845377091996991 4 P17612,P13861,P10644,P17252
Pka activation in glucagon signalling -0.4650014522218809 -0.29581713539709464 0.7673697362027034 1.0 0.9845377091996991 4 P17612,P13861,P10644,P17252
Gene silencing by rna 0.29641442275879526 0.2957287604676446 0.7674372313804549 1.0 0.9845377091996991 49 Q8N2A8,P30876,Q8N1F7,Q8NFH5,P57740,Q9Y2W6,Q8NFH4,Q9BTX1
Signaling by ptk6 -0.21958814066177842 -0.2955986730792157 0.7675365871036077 1.0 0.9845377091996991 15 P04150,P22681,P24941,P61586,P00533,P49023,P63000
Diseases associated with glycosaminoglycan metabolism -0.5792314510633609 -0.2949780703754275 0.768010632044972 1.0 0.9845377091996991 3 P07686
Signaling by erbb4 0.38455892989329893 0.29490781516955794 0.7680643016801034 1.0 0.9845377091996991 9
Post translational modification synthesis of gpi anchored proteins 0.4101293101501534 0.29249268258450845 0.7699099538477399 1.0 0.9857018246200319 6 Q92643,Q96S52
Ddx58 ifih1 mediated induction of interferon alpha beta -0.16314208023053894 -0.2908840884576163 0.7711399709529987 1.0 0.9857018246200319 18 O14920
Notch4 activation and transmission of signal to the nucleus -0.5903746515054412 -0.29061956675529954 0.7713422935888359 1.0 0.9857018246200319 2 P63104
Response of mtb to phagocytosis 0.3522010510497106 0.28917732052973727 0.7724456863829989 1.0 0.9857018246200319 13 P23246,P27361,O14964,P00558
Infection with mycobacterium tuberculosis 0.3522010510497106 0.28917732052973727 0.7724456863829989 1.0 0.9857018246200319 13 P23246,P27361,O14964,P00558
Competing endogenous rnas cernas regulate pten translation -0.5886792452830093 -0.28569749825273744 0.7751098209778342 1.0 0.9857695724477852 2 Q9HCE1,Q9UPQ9
Regulation of pten mrna translation -0.5886792452830093 -0.28569749825273744 0.7751098209778342 1.0 0.9857695724477852 2 Q9HCE1,Q9UPQ9
Trafficking of glur2 containing ampa receptors -0.3321633422165734 -0.2856154161082523 0.7751726947656639 1.0 0.9857695724477852 7 P53680,P17252,O94973,P46459,Q96CW1
Smac xiap regulated apoptotic response 0.5623266119603205 0.2854785317392134 0.775277549578385 1.0 0.9857695724477852 3
Signaling by notch2 -0.5877621696476768 -0.2830492194546749 0.7771391073571352 1.0 0.9858274538560113 2 Q04721
Notch2 activation and transmission of signal to the nucleus -0.5877621696476768 -0.2830492194546749 0.7771391073571352 1.0 0.9858274538560113 2 Q04721
Glutamate and glutamine metabolism 0.38650067025478263 0.28269940376626945 0.7774072733367701 1.0 0.9858274538560113 8
Ercc6 csb and ehmt2 g9a positively regulate rrna expression -0.21754097703540648 -0.2788770800475574 0.7803391584784423 1.0 0.9878774599785609 14 O95983,Q12873,Q86YP4,Q92769,O94776,Q13547,Q09028
Rna polymerase i promoter escape -0.14985422740524731 -0.27642896415249113 0.7822186128800876 1.0 0.9878774599785609 17 Q13185,O15446,P32780,Q3B726,P16104,Q9H9Y6,P62805,P17480,P62875,P19447,O95602,P18074,P52434,Q9GZS1,O15160,P19388,P84243
Eph ephrin mediated repulsion of cells -0.21409845616079362 -0.2752565260490673 0.7831191619843223 1.0 0.9878774599785609 14 Q00610,P07947,P53680,Q96CW1,O94973,P29317,P63010,P52735,Q92542,P09496,P63000,O95782,P07948,Q15375
Sensory processing of sound by outer hair cells of the cochlea -0.19842657342657502 -0.2747128077914369 0.7835368904243416 1.0 0.9878774599785609 15 P15311,Q14651,Q13813,P23634,Q12792,P35241,Q01082,P35579,Q00013,O14936,Q12965,Q9Y2J2,P26038,Q6IBS0,O00159
Interferon alpha beta signaling -0.23631429818389263 -0.27311410659733437 0.7847655033173344 1.0 0.9878774599785609 12 Q13325,P55265,Q9Y6K5,Q06124,P42224,P29597
Rna polymerase i transcription termination -0.22458900184964856 -0.2727408619357034 0.7850524217791066 1.0 0.9878774599785609 13 O15446,Q3B726,Q9H9Y6,P17480,O95602,Q9GZS1,P19447
Beta catenin independent wnt signaling 0.2947162192179906 0.27222716388012946 0.7854473565131022 1.0 0.9878774599785609 56 P28072,P28070,P49721,P60900
Dna damage reversal -0.4561529935942817 -0.27181798138651714 0.7857619784608163 1.0 0.9878774599785609 4 Q9C0B1
Sumoylation of dna replication proteins 0.30841910501584996 0.27084775073054596 0.7865081322135363 1.0 0.9878774599785609 35 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Notch4 intracellular domain regulates transcription 0.5515921350468637 0.2687048016902462 0.788156856430398 1.0 0.9878774599785609 2
Alk mutants bind tkis -0.32420692021803704 -0.2670463136984162 0.7894335022980885 1.0 0.9878774599785609 7 Q9HC35,Q9NR09
Base excision repair ap site formation -0.4044760280376613 -0.2666946006072937 0.7897043114898137 1.0 0.9878774599785609 5 P29372,P13051,P62805
Transcriptional regulation by ventx 0.3335135386658554 0.26364368915998054 0.7920544901015276 1.0 0.9878774599785609 17 Q9UJX2,Q96DE5,Q9UJX3
Regulation of insulin secretion 0.343201631780312 0.2636150151875364 0.7920765872430544 1.0 0.9878774599785609 14
Viral messenger rna synthesis 0.3075047920000015 0.26341790205193555 0.7922284938706796 1.0 0.9878774599785609 35 P30876,Q8N1F7,Q8NFH5,P57740,Q8NFH4,Q9BTX1
Constitutive signaling by ligand responsive egfr cancer variants -0.35576688600746365 -0.262221718994594 0.7931505097501204 1.0 0.9878774599785609 6 P00533,P22681
Signaling by egfr in cancer -0.35576688600746365 -0.262221718994594 0.7931505097501204 1.0 0.9878774599785609 6 P00533,P22681
Constitutive signaling by egfrviii -0.35576688600746365 -0.262221718994594 0.7931505097501204 1.0 0.9878774599785609 6 P00533,P22681
Endogenous sterols 0.5485727734329204 0.2618740104754882 0.793418577203614 1.0 0.9878774599785609 2
Transcriptional regulation by e2f6 -0.25652595008777523 -0.26125967404480716 0.7938922622951279 1.0 0.9878774599785609 10 Q09028,P38398,O75530
Other semaphorin interactions -0.5796796691770274 -0.2601458007672106 0.7947513098662826 1.0 0.9878774599785609 2 P05556
Attenuation phase -0.23690337601862702 -0.2595579790104644 0.7952047534676294 1.0 0.9878774599785609 11 P54652,P11142,Q02790,P25685,P08238,P50454,Q15185,P07900,P04792,Q92598,P0DMV9
Rna polymerase iii transcription -0.21141525917297493 -0.25921667532422477 0.7954680656692388 1.0 0.9878774599785609 13 Q12789,Q9UKN8,Q9NW08,Q8WUA4,O14802,Q9Y5Q8,P62875,P05455,Q9Y5Q9,P52434,Q9BUI4,O15160,P19388
Aryl hydrocarbon receptor signalling 0.5508130081300782 0.2588743866077082 0.7957321612089465 1.0 0.9878774599785609 3 O00170,Q15185
Lysosome vesicle biogenesis -0.1881736090882621 -0.25533222588791327 0.7984665119477292 1.0 0.9901035668739278 14 P15586,P11142,O14964,Q00610,O43747,Q9BXS5,Q8NBS9,P50570,Q10567,P20645,P09496,P51809,P61966,P05067
Cdc6 association with the orc origin complex 0.4244508347082389 0.2547440672073721 0.7989207780624716 1.0 0.9901035668739278 5
Wnt5a dependent internalization of fzd4 -0.26847004072134745 -0.25282073056747206 0.8004067473247247 1.0 0.9910795588601957 9 Q00610,P53680,P17252,Q96CW1,O94973,P63010,P32121,P09496,O95782
Platelet calcium homeostasis 0.4229663372362613 0.2503787109842853 0.8022944915786825 1.0 0.9914860598023403 5 P23634,P16615
Sema3a pak dependent axon repulsion -0.2929004124874398 -0.2496531094761868 0.8028556232725046 1.0 0.9914860598023403 8 P23528
Formation of apoptosome 0.546472732373785 0.2492289266006333 0.8031837050510353 1.0 0.9914860598023403 3 Q9NR28
Listeria monocytogenes entry into host cells -0.29241755162221256 -0.24878133644537545 0.8035299286629256 1.0 0.9914860598023403 8 Q99961,P22681
Degradation of cysteine and homocysteine 0.5457536064413993 0.24765138611771098 0.8044041484960573 1.0 0.9917024211258952 3
Rna polymerase iii transcription initiation from type 1 promoter -0.21135371179039697 -0.24612008861940493 0.8055892728226994 1.0 0.9920857610793421 12 Q12789,Q9UKN8,Q9NW08,Q8WUA4,O14802,Q9Y5Q8,P62875,Q9Y5Q9,P52434,Q9BUI4,O15160,P19388
Fgfr1 mutant receptor activation 0.3500639799677487 0.2430222808347339 0.8079881371641908 1.0 0.9920857610793421 11 O95684
Mitochondrial fatty acid beta oxidation 0.32987825350909494 0.24301985121949635 0.8079900193089096 1.0 0.9920857610793421 17 Q16836,P40939,P49748,Q8IVS2
Citric acid cycle tca cycle 0.3235026078515485 0.24205340262820346 0.8087387839547819 1.0 0.9920857610793421 19 Q13423,P48735
Dscam interactions -0.5577816492450707 -0.24143376961674926 0.8092189423489675 1.0 0.9920857610793421 3 Q16539,Q16512,P63000
Interleukin 1 family signaling 0.2910741775918649 0.2376890230085442 0.8121222980857055 1.0 0.9920857610793421 52 P28072,P28070,P49721,P60900
Interleukin 21 signaling -0.5559109518619852 -0.23700097135955778 0.8126560366884876 1.0 0.9920857610793421 3 P42224,P40763
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants -0.5559109518619852 -0.23700097135955778 0.8126560366884876 1.0 0.9920857610793421 3 P42224,P40763
Interleukin 9 signaling -0.5559109518619852 -0.23700097135955778 0.8126560366884876 1.0 0.9920857610793421 3 P42224,P40763
P130cas linkage to mapk signaling for integrins -0.5711466208414863 -0.2368384785103467 0.8127820991063601 1.0 0.9920857610793421 2 Q9Y490
Synthesis of pips at the golgi membrane 0.370993344975929 0.23681809603300658 0.8127979122331777 1.0 0.9920857610793421 9
Anti inflammatory response favouring leishmania parasite infection 0.3312623492538402 0.23565708227464308 0.8136987753542153 1.0 0.9920857610793421 16
Ncam signaling for neurite out growth -0.34403443550362045 -0.23552153717177501 0.8138039646908768 1.0 0.9920857610793421 6 P28482,O15020
Interleukin 10 signaling -0.5544680714971872 -0.23360863648794755 0.8152888223065506 1.0 0.9930427801313264 3 P29597,P40763
Egfr downregulation -0.2084371222684143 -0.23115599217684896 0.8171936173106868 1.0 0.9945092135196094 11 Q99961,P22681,P60953,P00533,Q9Y6I3,P42566
Glycerophospholipid catabolism 0.532137115357785 0.2268175183850564 0.8205656409903526 1.0 0.9965415716332238 2
Signaling by erbb2 in cancer -0.33793404689965284 -0.22258139165290877 0.8238613204633181 1.0 0.9965415716332238 6 Q96RT1,P00533
Signaling by erbb2 ecd mutants -0.33793404689965284 -0.22258139165290877 0.8238613204633181 1.0 0.9965415716332238 6 Q96RT1,P00533
Sema4d in semaphorin signaling -0.2761373636038287 -0.2220816515865853 0.8242503211390053 1.0 0.9965415716332238 8 Q13464,P63000,O75116,P61586
Apoptotic cleavage of cell adhesion proteins 0.3890528381859521 0.22205621607157558 0.8242701214524435 1.0 0.9965415716332238 6 Q07157,Q16625,P15924
Sumoylation of immune response proteins -0.5654571843251034 -0.22181119630304338 0.8244608631712154 1.0 0.9965415716332238 2 Q8N2W9,Q04206
Potential therapeutics for sars 0.2949913229417353 0.22147579846280033 0.8247219787481876 1.0 0.9965415716332238 41 P07437,P49356,O60341,Q99720
Cytochrome c mediated apoptotic response 0.4124675564126414 0.22039146902574414 0.8255662888193731 1.0 0.9965415716332238 5 Q9NR28
Activation of bad and translocation to mitochondria -0.27373406115501564 -0.21857659217637718 0.8269798886337454 1.0 0.9965415716332238 8 Q9Y3B8,P63104,P27348
Sumo is transferred from e1 to e2 ube2i ubc9 -0.5640570605737367 -0.2181772244799853 0.8272910298688778 1.0 0.9965415716332238 2 Q9UBT2
Processing and activation of sumo -0.5640570605737367 -0.2181772244799853 0.8272910298688778 1.0 0.9965415716332238 2 Q9UBT2
Sumo is conjugated to e1 uba2 sae1 -0.5640570605737367 -0.2181772244799853 0.8272910298688778 1.0 0.9965415716332238 2 Q9UBT2
Interactions of rev with host cellular proteins 0.3030943956097606 0.21650059803435895 0.828597559049975 1.0 0.9972688178896646 33 Q92621,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Downregulation of smad2 3 smad4 transcriptional activity -0.29396050982335475 -0.20758369981472985 0.8355540327926319 1.0 1.0 7 Q9UPN9,Q13547,O75376,Q93008,P09874
Mastl facilitates mitotic progression -0.3785978449562808 -0.20616106551024282 0.8366650997452729 1.0 1.0 5 Q96GX5,P14635
Nicotinate metabolism 0.5219810971249766 0.19886656368411076 0.8423671253931648 1.0 1.0 3
Condensation of prophase chromosomes 0.33740902474525847 0.19857762951688127 0.8425931541593743 1.0 1.0 12 P06493,P16104,Q01105,P62805,Q86XI2,P42695,Q9NTJ3,Q9UPP1,P53350,O95347,P84243
Cd28 co stimulation -0.21243200644810745 -0.19791053006734316 0.8431150653322583 1.0 1.0 9 P07947
Met activates ras signaling -0.5383023740015206 -0.1972225016198363 0.8436534226771504 1.0 1.0 3 Q96P70,Q96S59
Mitotic prometaphase 0.27826433072056345 0.19715919047020042 0.843702965033402 1.0 1.0 98 P41208,O43805,Q9BUF5,P07437,Q13885,P04350,O95684,P57740,O75935,Q9BVA1,O94927,Q8NFH4,P61163,P68371,Q96EA4
Dopamine neurotransmitter release cycle 0.5140783744557275 0.19250366619689357 0.8473476964089675 1.0 1.0 2 O14936
Adenylate cyclase inhibitory pathway 0.5185830429732905 0.19243566442369686 0.8474009582497719 1.0 1.0 3 P63096,P08754
Erbb2 regulates cell motility -0.5342231625202806 -0.18852012562020443 0.8504689403920938 1.0 1.0 3 P00533,P61586
Tcf dependent signaling in response to wnt 0.28540993466757913 0.1859313053591862 0.8524986321089194 1.0 1.0 64 P28072,P28070,P49721,P60900
Creb phosphorylation 0.5088452184411658 0.18338823224173753 0.8544934086018241 1.0 1.0 2
Beta oxidation of pristanoyl coa -0.41803511429193285 -0.18033595636764366 0.8568888292751597 1.0 1.0 4 O15254,P22307
Vitamin b5 pantothenate metabolism 0.3973092599676723 0.17995103203126503 0.8571910113063921 1.0 1.0 5 P49327
Cytosolic sulfonation of small molecules 0.3751633815568301 0.1793231254413143 0.8576839896792892 1.0 1.0 6 Q8TB61
Complement cascade 0.5062315273491956 0.17897465143902333 0.8579576055275178 1.0 1.0 2
Recognition and association of dna glycosylase with site containing an affected purine -0.4157413549397783 -0.17547989347746928 0.8607025683246501 1.0 1.0 4 P29372,P62805
Signaling by fgfr1 in disease 0.33226881391234075 0.17481083994741106 0.8612282704504128 1.0 1.0 12 O95684
Interleukin 15 signaling -0.5267373785233945 -0.17306315247971568 0.8626017879284249 1.0 1.0 3 P40763
Interleukin 7 signaling -0.5267373785233945 -0.17306315247971568 0.8626017879284249 1.0 1.0 3 P40763
Runx2 regulates genes involved in cell migration 0.49977341094697963 0.16846514185841902 0.8662173644796636 1.0 1.0 2
Vegfr2 mediated vascular permeability 0.3335273573923144 0.16776949615250228 0.8667646208619431 1.0 1.0 11 Q16512,P31751,P35221,P42345,P14923,O60716,P35222,P52735,P07900,Q13177
Rna polymerase iii transcription termination -0.22244838615877072 -0.16775876559898883 0.8667730629644219 1.0 1.0 8 Q9NW08,O14802,P62875,P05455,P52434,Q9BUI4,O15160,P19388
Erythropoietin activates phospholipase c gamma plcg 0.4989840348330853 0.16721909280698152 0.867197662043365 1.0 1.0 2 P07948
Signaling by fgfr4 in disease 0.49898403483308534 0.16721909280698152 0.867197662043365 1.0 1.0 2 P62993
Regulation of localization of foxo transcription factors -0.30488642671533234 -0.16381795141713068 0.8698744594065104 1.0 1.0 6 Q9Y3B8,P63104,P27348
Dap12 signaling -0.40968636540074427 -0.1630272977574526 0.870496941688673 1.0 1.0 4 P63000,P19174
Dex h box helicases activate type i ifn and inflammatory cytokines production -0.5214866434378631 -0.16262130873562974 0.8708166083863413 1.0 1.0 3 Q9H2U1,Q08211,Q04206
Runx2 regulates bone development -0.3546334339255758 -0.15946851008413088 0.8732997661243196 1.0 1.0 5 Q13951,P28482,P07947
Ngf stimulated transcription 0.4998455163587334 0.1594531798432776 0.8733118433580542 1.0 1.0 3
Signaling by ntrk3 trkc 0.499128919860631 0.15827539017117367 0.8742397994919482 1.0 1.0 3 P62993,Q8WX92
Negative feedback regulation of mapk pathway -0.5188119319364566 -0.15743006566154227 0.8749059199120564 1.0 1.0 3 Q02750,P28482
Activation of rac1 downstream of nmdars -0.5386516997605083 -0.15678525816927438 0.8754140914340904 1.0 1.0 2 P63000
P75ntr regulates axonogenesis 0.49790145134961294 0.15627225226461808 0.8758184270907028 1.0 1.0 3
Josephin domain dubs 0.4975831184874887 0.15575570792054214 0.8762255843899158 1.0 1.0 3 P54725
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway -0.5173796178853359 -0.1546857493436145 0.8770690651373108 1.0 1.0 3 P49916,Q96T60
G2 m dna replication checkpoint 0.4063807772519248 0.15307163463923543 0.8783417845119479 1.0 1.0 4
Purine salvage -0.2497220085192899 -0.1512958311392839 0.8797423576977395 1.0 1.0 7 P00492,P07741,Q01433
Rna polymerase iii chain elongation -0.24891125523504054 -0.15057324707992747 0.8803123664792658 1.0 1.0 7 Q9NW08
Rna polymerase iii transcription initiation from type 3 promoter -0.24891125523504054 -0.15057324707992747 0.8803123664792658 1.0 1.0 7 Q9NW08
Lipophagy 0.40458902120243734 0.14956688263094284 0.8811063380490671 1.0 1.0 4 P54646,O60664,P54619
Diseases of mismatch repair mmr -0.5145180023228793 -0.14927745036178608 0.8813347078990308 1.0 1.0 3 P52701,P43246,P20585
Synthesis of dna 0.2676144205152839 0.14681342103090192 0.8832792910265543 1.0 1.0 89 Q96DE5,Q9UJX2,P60900,Q9Y619,P28070,P28072,P41440,P49721,Q14566,Q14997
Estrogen dependent nuclear events downstream of esr membrane signaling 0.38128893675462205 0.14108033151792002 0.8878064814072646 1.0 1.0 5 P31751
Tlr3 mediated ticam1 dependent programmed cell death 0.47953555878083776 0.13913298044595102 0.8893450670480869 1.0 1.0 2 Q14790
Trif mediated programmed cell death 0.47953555878083776 0.13913298044595102 0.8893450670480869 1.0 1.0 2 Q14790
Robo receptors bind akap5 -0.5077717888473756 -0.1369220517922416 0.8910924081855365 1.0 1.0 3 P17612,P17252
Assembly of the orc complex at the origin of replication 0.3362120978731814 0.13624103364806986 0.8916307374123256 1.0 1.0 10
Cytochrome p450 arranged by substrate type 0.48382994055356476 0.13459673665887212 0.8929307218978972 1.0 1.0 3 Q16850
Growth hormone receptor signaling -0.2818352976037858 -0.13388278575108292 0.8934952627068196 1.0 1.0 6 P28482
Sema4d induced cell migration and growth cone collapse -0.223259215540973 -0.13252835990667097 0.8945663928968857 1.0 1.0 7 Q13464,O75116,P61586
Akt phosphorylates targets in the cytosol -0.5048785154549161 -0.13179340118032196 0.8951477061183384 1.0 1.0 3 Q96B36
Dna methylation -0.3341308322266744 -0.12678024442636868 0.8991143322151809 1.0 1.0 5 P26358,Q96T88
Non integrin membrane ecm interactions -0.27331298074158944 -0.12496302789911704 0.9005528203091933 1.0 1.0 6 P05556
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components -0.5008710801393692 -0.12485890768299136 0.9006352506372248 1.0 1.0 3 P49023,Q15404,P12814
Integrin cell surface interactions -0.38900555694136996 -0.12454228780324242 0.9008859201678427 1.0 1.0 4 P05556
Inositol phosphate metabolism -0.3324581149457179 -0.12440454861884764 0.9009949720508001 1.0 1.0 5 Q96PE3,Q9NPH2,Q01968
Inactivation of cdc42 and rac1 -0.49976036483948033 -0.12297170373973353 0.9021295050147919 1.0 1.0 3 P63000,P60953
Fbxw7 mutants and notch1 in cancer -0.5222060957910036 -0.12179481109616871 0.9030615235022672 1.0 1.0 2 Q13616,P63208
Dna replication initiation -0.1866083478858731 -0.11947590543036402 0.9048983279715872 1.0 1.0 7 Q14181,P09884
Transcriptional regulation by small rnas 0.28572004956492353 0.11909569562205145 0.9051995408698139 1.0 1.0 39 Q92621,P30876,P12270,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,P52434,Q8NFH4,Q9BTX1,P84243
Mecp2 regulates transcription of neuronal ligands -0.4971310582193516 -0.11856445275818116 0.9056204292338379 1.0 1.0 3 Q13547,Q96ST3
Activation of rac1 -0.2656687359315786 -0.11788125812691605 0.9061617435442813 1.0 1.0 6 P16333
Rsk activation 0.38666313283276266 0.11710442467774562 0.9067773034780044 1.0 1.0 4 P51812
Pi5p regulates tp53 acetylation -0.5163619244031646 -0.11028145233158688 0.9121861664291682 1.0 1.0 2 Q8TBX8
Role of abl in robo slit signaling -0.4917606445017577 -0.1098252872206794 0.9125479360475761 1.0 1.0 3 O75122,Q01518
Mapk family signaling cascades 0.26990902987764254 0.10917894710840599 0.9130605582509255 1.0 1.0 96 P07196,O60725,O43924,P60900,Q16181,P28070,P49356,P28072,P49721,P27361,Q14168,Q12959,Q14997
Establishment of sister chromatid cohesion 0.3386627906976683 0.10633675985119223 0.9153151667740052 1.0 1.0 7 Q9UQE7,Q7Z5K2,Q14683,Q8N3U4,Q9NTI5,Q29RF7
Signaling by pdgfr in disease 0.3650014332341237 0.10582039220626308 0.9157248569911518 1.0 1.0 5 O43815
Retrograde neurotrophin signalling 0.3381797034021442 0.10479949288637777 0.91653491245272 1.0 1.0 8 P53680,Q00610,Q96CW1,P63010,P50570,P09496,O95782
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.33808139534883186 0.10464337656262851 0.9166587941122573 1.0 1.0 7 P53680,Q00610,Q96CW1,P63010,P09496,O95782
Vldlr internalisation and degradation 0.33808139534883186 0.10464337656262851 0.9166587941122573 1.0 1.0 7 P53680,Q00610,Q96CW1,P63010,P09496,O95782
Rho gtpases activate cit 0.32772370309633614 0.10332614160418986 0.9177041286561818 1.0 1.0 10
Defective ripk1 mediated regulated necrosis 0.45905923344948163 0.10210992310776053 0.9186694246853135 1.0 1.0 3 Q14790,Q13546
Tnfr1 induced proapoptotic signaling 0.45905923344948163 0.10210992310776053 0.9186694246853135 1.0 1.0 3 Q14790,Q13546
Neurotransmitter clearance 0.4458635703918655 0.1018180105117432 0.9189011296242584 1.0 1.0 2 P21964
Glutamate neurotransmitter release cycle -0.4863530778164888 -0.10138140782251086 0.9192476948326838 1.0 1.0 3 Q13136,O94925,O75915
Runx1 regulates expression of components of tight junctions 0.4553567435086969 0.09785878532895959 0.922044427391302 1.0 1.0 3 Q16625
Synthesis of bile acids and bile salts 0.344667247893058 0.09701731116873584 0.922712646975155 1.0 1.0 6 P22059,O14975,P51659,Q9H4L5,P22307
Bile acid and bile salt metabolism 0.344667247893058 0.09701731116873584 0.922712646975155 1.0 1.0 6 P22059,O14975,P51659,Q9H4L5,P22307
Small interfering rna sirna biogenesis 0.37322102817310454 0.09585988064099518 0.9236318584000178 1.0 1.0 4 Q99598,Q9UPY3,O75569
Keratinization 0.3438598859007851 0.09506644835002404 0.9242620476809675 1.0 1.0 6
Formation of the cornified envelope 0.3438598859007851 0.09506644835002404 0.9242620476809675 1.0 1.0 6
Leishmania infection 0.2749945089770006 0.09230262648058189 0.9264576016508554 1.0 1.0 48 O43865,P09601
Signal attenuation -0.4802464912947225 -0.09227336300693112 0.9264808513040506 1.0 1.0 3 P28482
Senescence associated secretory phenotype sasp 0.2913121044759105 0.08966188646495414 0.9285559041005207 1.0 1.0 25 Q96DE5,Q9UJX3,P51812,P27361,Q9UJX2
Response to elevated platelet cytosolic ca2 0.28566352043080256 0.08587864570708509 0.9315628870431865 1.0 1.0 33 Q8NBX0,O43852,Q8NBM8,Q6UXV4,Q9NZJ7,Q9NUQ9,P07602,P10909
Dna replication pre initiation 0.27512472162566237 0.08507279409287596 0.9322035190471152 1.0 1.0 67 P60900,Q9Y619,P28070,P28072,P49721,Q14997
Early phase of hiv life cycle 0.3313146282709574 0.08310144353806191 0.9337708780410852 1.0 1.0 8
Synthesis of ip3 and ip4 in the cytosol -0.5013062409288883 -0.08285851954300179 0.9339640371838671 1.0 1.0 2 Q01968,P19174
Egfr interacts with phospholipase c gamma -0.5013062409288883 -0.08285851954300179 0.9339640371838671 1.0 1.0 2 P00533,P19174
Role of second messengers in netrin 1 signaling -0.5013062409288883 -0.08285851954300179 0.9339640371838671 1.0 1.0 2 Q00169,P19174
Nrcam interactions -0.5008722088790726 -0.08211569927098761 0.9345547090725641 1.0 1.0 2 Q15334
Ionotropic activity of kainate receptors -0.5008722088790726 -0.08211569927098761 0.9345547090725641 1.0 1.0 2 Q15334
Activated notch1 transmits signal to the nucleus -0.47276818586671887 -0.0817323029337823 0.9348595902588053 1.0 1.0 3 P32121,Q96J02
Nef mediated cd8 down regulation 0.3379831444347656 0.0812332682709643 0.9352564426785024 1.0 1.0 6 P53680,Q9UI12,P63010,O95782,Q96CW1
Nef mediated cd4 down regulation 0.3379831444347656 0.0812332682709643 0.9352564426785024 1.0 1.0 6 P53680,Q9UI12,P63010,O95782,Q96CW1
Interleukin 35 signalling -0.2882375905299671 -0.07646406970334073 0.9390498984808548 1.0 1.0 5 P42224,P29597,P40763
Interleukin 27 signaling -0.2882375905299671 -0.07646406970334073 0.9390498984808548 1.0 1.0 5 P42224,P29597,P40763
Polo like kinase mediated events 0.3275334819554403 0.07512035939908737 0.9401189491334732 1.0 1.0 7
Traf6 mediated irf7 activation -0.4625435540069652 -0.06839778048592278 0.9454689886101808 1.0 1.0 3 Q12933,Q14258,Q7Z434
Aspartate and asparagine metabolism -0.2742965580558494 -0.06668889188844443 0.9468293776143346 1.0 1.0 5 P08243,P17174,P00505
Mitotic telophase cytokinesis 0.3065502183406059 0.06482357385022747 0.9483144717040992 1.0 1.0 12 Q02241,Q9UQE7,O60216,Q7Z5K2,Q9Y6X3,Q14683,O95235,Q8N3U4,Q9NTI5,P53350,Q29RF7
Free fatty acids regulate insulin secretion -0.48837748191950625 -0.061869985751372626 0.9506663695918467 1.0 1.0 2 O60488
E2f mediated regulation of dna replication 0.3057023301852215 0.06147544403561568 0.9509805702300662 1.0 1.0 12
Runx1 regulates estrogen receptor mediated transcription 0.3730108062146419 0.060550320838773666 0.9517173391048979 1.0 1.0 2
Mismatch repair 0.30496828594956754 0.058592224653948935 0.9532769038718891 1.0 1.0 12
Receptor type tyrosine protein phosphatases -0.4862119013062468 -0.05858314122842859 0.953284138968914 1.0 1.0 2 P10586,Q13136
Transcriptional regulation by runx2 0.2724467783826357 0.054955409047921434 0.9561739884984148 1.0 1.0 53 P28072,P28070,P49721,P60900
Mrna editing 0.34862119013061826 0.05494269989352609 0.9561841136390257 1.0 1.0 2 Q9NRW3
Traf6 mediated induction of tak1 complex within tlr4 complex 0.33933236574745396 0.05347637475702918 0.9573523539217075 1.0 1.0 2 Q6SZW1
Signaling by activin -0.48156957838595266 -0.05175577481728277 0.9587232948744027 1.0 1.0 2 P28482
Signaling by nodal -0.48156957838595266 -0.05175577481728277 0.9587232948744027 1.0 1.0 2 P28482
Ptk6 regulates cell cycle 0.3190130624092824 0.05121721001797318 0.9591524382312222 1.0 1.0 2 P11802
Sensing of dna double strand breaks -0.23271353864032715 -0.04898311602719825 0.960932751245156 1.0 1.0 5 P49959,O60934,Q13315,Q92878,P52292
Notch3 intracellular domain regulates transcription 0.39207292725159004 0.046858892390599 0.9626256912013318 1.0 1.0 3
Formyl peptide receptors bind formyl peptides and many other ligands 0.3919860627177746 0.04681366760808268 0.9626617358009892 1.0 1.0 3 P05067,P04083
Signaling by fgfr 0.2840183675467306 0.04574472583534477 0.9635137150393889 1.0 1.0 25 P30876,P31483,P31943,P52597,Q01085
Signaling by fgfr2 0.2840183675467306 0.04574472583534477 0.9635137150393889 1.0 1.0 25 P30876,P31483,P31943,P52597,Q01085
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.3890824622531981 0.04533509388685583 0.9638402153070833 1.0 1.0 3 P51659,O14975
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.32384548358989 0.0394711077587671 0.9685147882275866 1.0 1.0 4 Q9UIW2,P63000,O14786
Activation of the ap 1 family of transcription factors -0.43420946343116884 -0.03769534065025032 0.9699305909807368 1.0 1.0 3 Q16539,P28482
Interleukin 23 signaling 0.36962833914053855 0.03697950016206072 0.970501351059943 1.0 1.0 3 P07237,P40763
Antimicrobial peptides -0.43331161602885815 -0.036865804869672315 0.9705920049638317 1.0 1.0 3 P81605
Clathrin mediated endocytosis 0.2708783598241332 0.03255843031408002 0.9740267200446999 1.0 1.0 59 Q9UBC2,P02786,Q14108
Gastrin creb signalling pathway via pkc and mapk 0.30900393160183826 0.028929166410665733 0.9769210839202569 1.0 1.0 7 P51812
Pp2a mediated dephosphorylation of key metabolic factors -0.4240369676836814 -0.02878323320087249 0.9770374733074942 1.0 1.0 3 P30153,Q14738
Vitamin c ascorbate metabolism 0.3392389607793421 0.028433573524041963 0.9773163472195132 1.0 1.0 3 P78417
Phosphorylation of emi1 0.33652729384437124 0.027886557245201078 0.9777526300393726 1.0 1.0 3 P53350,P06493
Ra biosynthesis pathway 0.3260743321718981 0.026046784875814504 0.9792200221596499 1.0 1.0 3 Q8NBN7,Q9HBH5
Diseases of dna repair 0.29230949450282934 0.025340310080939975 0.9797835214492716 1.0 1.0 14
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.3191056910569152 0.02503420649148563 0.9800276793174372 1.0 1.0 3 Q00534,P11802
Apobec3g mediated resistance to hiv 1 infection -0.4158922101891466 -0.02239301556484505 0.9821344517281678 1.0 1.0 3 O75475
Slbp dependent processing of replication dependent histone pre mrnas -0.29111293721893616 -0.022050656017107928 0.9824075476871366 1.0 1.0 4 P62318
Sumoylation of dna methylation proteins 0.2767074524474762 0.021518885132105196 0.9828317387937169 1.0 1.0 3
Activation of smo 0.25929152148664814 0.02092321452595787 0.9833069081624028 1.0 1.0 3 Q9Y496,P48729
Aflatoxin activation and detoxification -0.39882177392766627 -0.0109999876662501 0.991223456665661 1.0 1.0 3 O43488
Met activates ptk2 signaling -0.4437607249285354 -0.006780040508966715 0.9945903518022832 1.0 1.0 2 P05556
Laminin interactions -0.4437607249285354 -0.006780040508966715 0.9945903518022832 1.0 1.0 2 P05556
Transcriptional regulation by runx1 0.2648350705924484 0.00676752854604696 0.9946003346752916 1.0 1.0 75 O00231,Q8TAQ2,Q9C005,P20618,Q8IXK0,P60900,P48556,Q9HCL2,P28070,Q969G3,Q03164,Q86U86,P49721,P28072,Q16625,Q06323,O15047,Q14997
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.25907638687191115 0.006744595174714518 0.9946186324406048 1.0 1.0 4 P05141,P12236,P12235
Cohesin loading onto chromatin 0.3062827225130937 0.006139226136361517 0.9951016370205021 1.0 1.0 9 Q9UQE7,O60216,Q7Z5K2,Q9Y6X3,Q14683,Q8N3U4,Q9NTI5,Q29RF7
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation -0.38671827122368163 -0.004421971004005372 0.9964717891059278 1.0 1.0 3 P46087,P10809
Ecm proteoglycans -0.37782619287721336 -0.00030261069032357346 0.999758551605942 1.0 1.0 3 P05556
Hur elavl1 binds and stabilizes mrna 0.23938764771860332 0.0 1.0 1.0 1.0 7
Rho gtpases activate pkns 0.27582865822291 0.0 1.0 1.0 1.0 20
Nef mediated downregulation of mhc class i complex cell surface expression 0.2610164351901131 0.0 1.0 1.0 1.0 5 Q10567,P04439
Sars cov infections 0.24962982796426883 0.0 1.0 1.0 1.0 64 Q13724,P07437,Q96FZ7,P49356,Q10472,Q14839,O60341,P46977,P05023,Q99720
Pre notch processing in the endoplasmic reticulum -0.42285777976708205 0.0 1.0 1.0 1.0 2 Q04721
Signaling by interleukins 0.25700055416824835 0.0 1.0 1.0 1.0 117 P09601,P60900,P51812,P28070,O14979,Q13126,P08670,P28072,P49721,P52597,Q14997
Metalloprotease dubs 0.2168363281949024 0.0 1.0 1.0 1.0 8 Q9NXR7
Meiotic synapsis 0.2276116380051408 0.0 1.0 1.0 1.0 15 P20700,Q9UH99,P02545,Q8WXH0
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.21187427240977674 0.0 1.0 1.0 1.0 11 P04439,P53680,O94973,O43747,Q9UI12,Q9BXS5,P63010,Q10567,O95782,Q96CW1
Translation of sars cov 2 structural proteins 0.24123632980852866 0.0 1.0 1.0 1.0 16 Q16706,Q13724,Q10472,P04843,Q9H0U3,P46977,P27824
Processing of capped intronless pre mrna 0.1940182227505787 0.0 1.0 1.0 1.0 19 Q8N684,P52298,P33240,Q6UN15,Q5KU26
Tp53 regulates metabolic genes 0.17763966663566416 0.0 1.0 1.0 1.0 37 P13073,P31751,P09669,P00403
Antiviral mechanism by ifn stimulated genes 0.26464084836259255 0.0 1.0 1.0 1.0 51 Q8N1F7,Q8NFH5,P57740,P27361,Q8NFH4,Q9BTX1,P46934
Signaling by flt3 fusion proteins 0.2855897733875598 0.0 1.0 1.0 1.0 5 Q14789,Q01082,P62993,Q92614
Cytosolic sensors of pathogen associated dna 0.16024613137820795 0.0 1.0 1.0 1.0 22 P49959,P12956,P19474,O15160
Rhou gtpase cycle 0.25968583955709146 0.0 1.0 1.0 1.0 20 O14964,O96013,Q8TAA9,P46940,O43396,P29317
Sars cov 2 infection 0.20464146774011965 0.0 1.0 1.0 1.0 23 Q16706,Q13724,Q10472,P04843,Q9H0U3,P46977,P27824,P61803,Q96FZ7
G2 m checkpoints 0.2378246564969891 0.0 1.0 1.0 1.0 93 Q9UQ84,P60900,Q9Y619,P28070,P28072,P49721
Regulation of mrna stability by proteins that bind au rich elements 0.2628961920227377 0.0 1.0 1.0 1.0 67 P60900,P28070,Q01105,P28072,P49721,Q14103,Q14997
Apoptosis 0.2324734634547196 0.0 1.0 1.0 1.0 94 P31751,P49327,P20618,P60900,P28070,P08670,Q9NR28,P28072,P49721,P27361,Q16625,Q14997
Snrnp assembly 0.24584403796650217 0.0 1.0 1.0 1.0 40 Q16637,Q92621,P12270,P52298,P62304,Q12769,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Signaling by retinoic acid 0.24170064065229807 0.0 1.0 1.0 1.0 13 P50416,Q01469,Q8NBN7,P09622,Q9HBH5,Q15120,P28702,Q8TC12,P08559,P11177,Q15118,O00330
Class i mhc mediated antigen processing presentation 0.2302875273460264 0.0 1.0 1.0 1.0 119 P60900,P28070,Q9UIQ6,P28072,P49721,P55786,P46934,Q14997
Antigen processing ubiquitination proteasome degradation 0.25153503641685787 0.0 1.0 1.0 1.0 97 P60900,P28070,Q9UIQ6,P28072,P49721,P55786,P46934
Mitochondrial translation 0.19691892278786496 0.0 1.0 1.0 1.0 55 Q13405,Q9NRX2,O75616,P82663,Q9BRJ2,P52815,Q8TAE8,Q96RP9,Q15070,Q9Y3D9,Q9Y2R9,Q9Y3D3,Q9NYK5
The role of nef in hiv 1 replication and disease pathogenesis 0.2119976703552683 0.0 1.0 1.0 1.0 13 P04439,Q96CW1,P53680,O94973,O43747,Q9UI12,Q9BXS5,P63010,Q10567,P63000,O95782,Q13177
Processing of intronless pre mrnas 0.21093413991836918 0.0 1.0 1.0 1.0 17 Q5KU26,Q8N684,P52298,P33240
Programmed cell death 0.24314148524501183 0.0 1.0 1.0 1.0 107 P31751,P49327,P20618,P60900,Q96FZ7,P28070,P08670,Q9NR28,P28072,P41440,P49721,Q16625,P27361,Q14997
Post translational protein modification 0.24564438245335476 0.0 1.0 1.0 1.0 416 P21796,P45880,Q9BU89,P49721,P46977,P45973,Q02818,P04439,O60826,P24390,Q8IXK0,Q8NB78,Q969Q5,P28072,P53611,P61163,P68371,Q96S52,P10619,Q13561,P28070,Q13885,Q14789,Q9BT22,P54725,P25054,Q9BTA9,Q13190,Q86YN1,O43505,O14964,Q13217,Q15388,Q9Y2B2,Q7Z3B4,Q06323,P54727,O95630,P49366,O00231,O43852,P60900,P48556,P04350,P38435,Q96JB2,Q9BUN8,O43731,Q9BTX1,Q14997,O43493,P07237,P12270,P20339,Q9BUF5,P28074,O75935,O60725,Q15363,O76024,Q9BTY2,Q13438,P41208,Q9Y3B3,Q92905,P61978,Q08379,Q8NFH5,Q96RU2,Q8N1F7,Q9BVA1,Q13724,P07910,Q9NXR7,P07942,Q9HA64,P49755,P53602,Q15907,Q15286,Q10472,Q96K76,P57740,O95249,Q07065,Q8NFH4,Q96PC5,O94826,Q9UJW0,Q92643,Q92621,P20618,Q8NAT1
Resolution of sister chromatid cohesion 0.24983833566546282 0.0 1.0 1.0 1.0 66 Q9BUF5,Q13885,P04350,P57740,Q9BVA1,Q96EA4
Signaling by rho gtpases miro gtpases and rhobtb3 0.2761853668762231 0.0 1.0 1.0 1.0 277 P02786,Q9UNZ2,P51648,O75976,P30519,Q13505,Q86XL3,Q96EA4,P38159,Q9P0I2,P62995,P04350,P27105,P57740,Q07065,Q8NFH4,P42167,Q9BUF5,Q8IWA4,P78371,Q13885,P08670,Q15058,P50402,O60341,P27361,O43396,O15173,Q9BVA1,Q86YQ8,Q8N684,P61604,P20700,O95140,O96013,Q86Y07,P07910,P41440,Q9UQB8
Activation of ppargc1a pgc 1alpha by phosphorylation -0.35914371538984424 0.0 1.0 1.0 1.0 3 Q16539
Signaling by wnt in cancer 0.23531122745782898 0.0 1.0 1.0 1.0 9 P30154,P30153,P48729,Q14738,P25054,Q13362,P56545,P35222
Neutrophil degranulation 0.1873559612813355 0.0 1.0 1.0 1.0 176 Q9Y315,P11717,Q5T9A4,P10321,P30519,Q9Y5K8,P31949,P04439,O75874,P61916,Q969Q5,Q9NZJ7,O00264,Q9H7Z7,P27105,P42785,Q9NQX7,Q07065,P68371,Q4KMQ2,P10619,P07437,Q93050,P12956,P78371,P17900,P09960,Q9BS26,P07602,P20618,Q9BTY2
Energy dependent regulation of mtor by lkb1 ampk 0.23171614520800118 0.0 1.0 1.0 1.0 7 P54646,Q9Y2Q5
Mitotic g1 phase and g1 s transition 0.25213797222158724 0.0 1.0 1.0 1.0 83 Q9Y619,P28070,P00374,P28072,P49721
Deactivation of the beta catenin transactivating complex 0.23537969159149785 0.0 1.0 1.0 1.0 10 P31751,O14980,Q15291,Q04726,P63104,Q9UBL3,P25054,Q13547,P35222
Camk iv mediated phosphorylation of creb -0.3578823835148594 0.0 1.0 1.0 1.0 2 Q13555
Regulation of hsf1 mediated heat shock response 0.24384604972263443 0.0 1.0 1.0 1.0 53 Q92621,O95817,O95757,Q8N1F7,Q99543,Q8NFH5,Q7Z3B4,P57740,P27361,O95429,Q8NFH4,Q9BTX1
Negative regulators of ddx58 ifih1 signaling 0.25261627906976064 0.0 1.0 1.0 1.0 7 Q15366,Q9UII4,Q86UT6,Q96J02,Q7Z434,P61086
Translation of replicase and assembly of the replication transcription complex 0.2905316906993597 0.0 1.0 1.0 1.0 5
Signaling by cytosolic fgfr1 fusion mutants 0.2929423887156035 0.0 1.0 1.0 1.0 9
Signaling by wnt 0.22202732009262288 0.0 1.0 1.0 1.0 89 P28072,P28070,P49721,P60900
Amino acids regulate mtorc1 0.1696537133880769 0.0 1.0 1.0 1.0 11 Q9Y5K8,Q9Y2Q5
Regulation of pten gene transcription 0.2590071365714526 0.0 1.0 1.0 1.0 21 P27361,Q14839,O60341,Q8IXK0
Suppression of phagosomal maturation 0.20872093023254923 0.0 1.0 1.0 1.0 7 P20339,O14964,P52294,Q9UI12,P51149,Q9H267
Deadenylation of mrna 0.23731328421641884 0.0 1.0 1.0 1.0 17 P23588,O95453,Q504Q3
Transport of mature transcript to cytoplasm 0.257119923389046 0.0 1.0 1.0 1.0 65 Q13242,Q92621,P12270,Q86V81,P52298,Q07955,Q12769,Q16629,Q9Y5S9,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q6UN15,Q8NFH4,Q9BTX1,P82979
Membrane trafficking 0.24940922702650767 0.0 1.0 1.0 1.0 260 P02786,P31751,P11717,O75976,P49755,Q7Z6M1,Q9UIQ6,Q9P2W9,Q8IWF6,Q9Y3B3,Q15907,Q92905,Q15286,P24390,Q9Y5X3,Q92845,Q08379,Q10472,P04350,O00461,O60749,O95249,P55327,P61163,P68371,O43731,Q8TBA6,Q96PC5,Q9H3P7,Q8TD16,Q14108,Q9BUF5,Q13561,Q13885,Q9UJW0,O75935,Q14789,O15260,Q9BVA1,Q96FZ7,Q9UBC2,Q6NUQ1,Q15363,Q13190,Q9Y5X1,Q9Y496
Sumoylation of dna damage response and repair proteins 0.25012919480191786 0.0 1.0 1.0 1.0 44 P41208,Q92621,Q8IXK0,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q8NFH4,Q9BTX1
Deadenylation dependent mrna decay 0.23225504135873998 0.0 1.0 1.0 1.0 42 Q504Q3,Q969T7,Q6PGP7
Glucose metabolism 0.21215993514176368 0.0 1.0 1.0 1.0 61 Q92621,Q9UBX3,P00558,Q8N1F7,Q9BRR6,P57740,Q8NFH5,Q02978,Q8NFH4,Q9BTX1
Signaling by receptor tyrosine kinases 0.20721951125509383 0.0 1.0 1.0 1.0 130 P31751,P30876,P07942,P31483,P31943,O43865,Q93050,P51812,Q9Y487,Q9UBC2,P52597,Q9UQB8,P46934,Q01085
Interferon signaling 0.2059086416818806 0.0 1.0 1.0 1.0 65 Q92621,P19474,P10321,Q8N1F7,Q8NFH5,Q7Z3B4,P57740,Q9BTX1,P27361,Q8NFH4,P04439,P46934
Glycolysis 0.24059741379311647 0.0 1.0 1.0 1.0 50 P00558,Q8N1F7,Q9BRR6,P57740,Q8NFH5,Q8NFH4,Q9BTX1
Signaling by vegf 0.26514467641126616 0.0 1.0 1.0 1.0 36 O43865
Resolution of d loop structures 0.2692179950722004 0.0 1.0 1.0 1.0 12
Rho gtpase effectors 0.21018973594689275 0.0 1.0 1.0 1.0 124 Q13885,P04350,Q15058,O60341,Q9UQB8,Q96EA4
Golgi cisternae pericentriolar stack reorganization 0.2381420923789679 0.0 1.0 1.0 1.0 11 Q08379
Cell cycle checkpoints 0.20040439156300693 0.0 1.0 1.0 1.0 155 Q96DE5,Q9UJX2,Q9UJX3,Q9UQ84,P60900,Q9Y619,P28070,P28072,P49721,Q14566,Q96EA4,Q14997
Transcriptional regulation of granulopoiesis 0.26961850760818107 0.0 1.0 1.0 1.0 9
Mitotic spindle checkpoint 0.18327811031227775 0.0 1.0 1.0 1.0 60 Q96DE5,Q9UJX3,P57740,Q9UJX2,Q8NFH4,Q96EA4
Late endosomal microautophagy 0.24517624526724258 0.0 1.0 1.0 1.0 10 P08670
Hiv infection 0.19806711308109703 0.0 1.0 1.0 1.0 141 Q92621,Q8IXH7,P30876,P60900,Q96FZ7,P28070,P12956,Q8N1F7,Q8NFH5,P57740,P28072,P49721,Q8NFH4,Q92804,Q9BTX1,Q14997
Plasma lipoprotein assembly -0.25126913806874235 0.0 1.0 1.0 1.0 3 P17612,P17252
Host interactions of hiv factors 0.23293668357999595 0.0 1.0 1.0 1.0 95 Q92621,P60900,P28070,Q8N1F7,Q8NFH5,P57740,P28072,P49721,Q8NFH4,Q9BTX1,Q14997
Signaling by notch 0.2350250432077234 0.0 1.0 1.0 1.0 65 P28072,P28070,P49721,P60900
Rho gtpases activate formins 0.2373862904798832 0.0 1.0 1.0 1.0 64 Q9BUF5,Q13885,P04350,P57740,Q9BVA1,Q96EA4
Processing of capped intron containing pre mrna 0.31630972112595457 0.0 1.0 1.0 1.0 191 P51991,P33240,P62304,P62312,Q9UBB9,Q7Z3B4,P35637,Q15637,Q5KU26,P52597,O75533,P52272,P61978,O75937,O95400,Q13242,P38159,P30876,Q86V81,P62995,Q16629,Q8NFH5,P57740,P52756,Q8NFH4,Q9BTX1,Q13151,P22626,Q6P2Q9,P12270,O75494,O43290,Q9BUJ2,P31943,P55795,Q12874,Q9BZJ0,Q9Y5S9,Q8N1F7,Q9H2H8,Q15427,Q14103,Q92621,Q8N684,P52298,O43390,Q07955,Q8WUA2,Q8IWX8,P07910,Q9P013,Q6UN15,Q92733,Q13573
Cell cycle 0.23056639930379919 0.0 1.0 1.0 1.0 323 P41208,P31751,Q9UQ84,P04818,P49721,Q14566,Q86XL3,Q96EA4,Q96DE5,P30876,P60900,Q08379,P04350,O95684,P00374,Q8NFH5,P57740,P28072,Q9UJX2,O94927,Q8NFH4,Q9BTX1,Q9NY12,Q14997,Q9UJX3,P42167,Q9BUF5,Q99640,P07437,P28070,Q13885,Q01105,Q8N1F7,P50402,O75935,P27361,Q9BVA1,Q96FZ7,Q92621,P20618,Q9Y619,Q86Y07,P41440,Q9NXR7
S phase 0.24741209618747406 0.0 1.0 1.0 1.0 100 Q96DE5,Q9UJX2,P60900,Q9Y619,P28070,P28072,P41440,P49721,Q14566,Q14997
Cell cycle mitotic 0.2585655102150617 0.0 1.0 1.0 1.0 271 P41208,P31751,P04818,P49721,Q14566,Q86XL3,Q96EA4,Q96DE5,P60900,Q08379,P04350,O95684,P00374,Q8NFH5,P57740,P28072,Q9UJX2,O94927,Q8NFH4,Q9BTX1,Q14997,Q9UJX3,P42167,Q9BUF5,Q99640,P07437,P28070,Q13885,Q01105,Q8N1F7,P50402,O75935,P27361,Q9BVA1,Q96FZ7,Q92621,P20618,Q9Y619,Q86Y07,P41440
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.2692179950722004 0.0 1.0 1.0 1.0 12
Dna replication 0.25243517661212067 0.0 1.0 1.0 1.0 96 Q96DE5,Q9UJX2,P60900,Q9Y619,P28070,P28072,P41440,P49721,Q14566,Q14997
Regulation of pyruvate dehydrogenase pdh complex 0.24134922942715314 0.0 1.0 1.0 1.0 8 P09622,Q8NCN5,Q15120,P11177,P08559,Q15118,O00330
Cytokine signaling in immune system 0.21310683637406883 0.0 1.0 1.0 1.0 185 P31751,Q13126,P10321,P49721,P52597,P60900,P51812,O14979,Q8NFH5,P57740,P28072,Q8NFH4,P22626,Q9BTX1,Q14997,P09601,P28070,P08670,Q8N1F7,P27361,Q92621,P20618,P46934
Adaptive immune system 0.2311437525024829 0.0 1.0 1.0 1.0 200 Q9NZ08,Q9BUF5,P60900,P10619,O43865,P28070,Q13885,P04350,Q9UIQ6,P28072,P49721,P55786,P46934,Q14997
Stimuli sensing channels 0.30055646735720787 0.0 1.0 1.0 1.0 9 P27105,Q4KMQ2
Copii mediated vesicle transport 0.1658375066745708 0.0 1.0 1.0 1.0 32 Q15363,Q08379,Q8IUR0,Q92734,P49755,Q9Y296,Q13190
Vesicle mediated transport 0.27097567314911103 0.0 1.0 1.0 1.0 268 P02786,P31751,P11717,O75976,P49755,Q8WTV0,Q7Z6M1,Q9UIQ6,Q8IWF6,Q5KU26,Q9P2W9,Q07954,Q9Y3B3,Q92905,Q15907,Q15286,P24390,Q9Y5X3,Q92845,Q08379,Q10472,P04350,O00461,O60749,O95249,P55327,P61163,P68371,O43731,Q8TBA6,Q96PC5,Q9H3P7,Q8TD16,Q14108,Q9BUF5,Q13561,Q13885,Q9UJW0,O75935,Q14789,O15260,Q9BVA1,Q96FZ7,Q9UBC2,Q6NUQ1,Q15363,Q13190,Q9Y5X1,Q9Y496
Regulated proteolysis of p75ntr -0.41824272812937224 0.0 1.0 1.0 1.0 2 Q04206
Rab geranylgeranylation 0.2771302664953093 0.0 1.0 1.0 1.0 20 Q15286,P20339,Q969Q5,Q15907,P53611
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.20642121427755694 0.0 1.0 1.0 1.0 15 Q03164
Nostrin mediated enos trafficking -0.42399747825001244 0.0 1.0 1.0 1.0 2 O00401
Extracellular matrix organization 0.23005540252392556 0.0 1.0 1.0 1.0 28 P13674,P07942,P07237,O60568,Q32P28,P35613,O75718
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.19796321876964418 0.0 1.0 1.0 1.0 16 Q86U86,Q969G3,Q8IXK0
Fcgamma receptor fcgr dependent phagocytosis 0.26622254331608924 0.0 1.0 1.0 1.0 39 O43865,Q9UQB8
Synthesis of pips at the er membrane -0.3260740375797681 0.0 1.0 1.0 1.0 3 Q13614
Sumoylation 0.15418364882434565 0.0 1.0 1.0 1.0 79 P41208,Q92621,Q8N1F7,P07910,Q8NFH5,P57740,Q9BTX1,P45973,Q8NFH4,P61978
Smooth muscle contraction 0.2245195107746053 0.0 1.0 1.0 1.0 13 Q16512,P08133,P67936,P60660,P06753,P04083,P18206,Q05682,P07355,Q9Y490,P09493,Q13177
M phase 0.3078950364737688 0.0 1.0 1.0 1.0 203 P41208,P49721,Q86XL3,Q96EA4,Q96DE5,O43805,P60900,Q08379,P04350,O95684,Q8NFH5,P57740,P28072,Q9UJX2,O94927,Q8NFH4,P61163,Q9BTX1,P68371,Q14997,Q9UJX3,P42167,Q9BUF5,P07437,P28070,Q13885,Q01105,Q8N1F7,P50402,O75935,P27361,Q9BVA1,Q96FZ7,Q92621,P20618,P20700,Q86Y07,Q9UJX4
Cellular response to heat stress 0.2004616775867719 0.0 1.0 1.0 1.0 60 Q92621,Q8N1F7,Q99543,Q8NFH5,P57740,P27361,O95817,Q8NFH4,Q9BTX1
Rhof gtpase cycle 0.19771246498254427 0.0 1.0 1.0 1.0 22 Q9Y6M7,P20700,P42167,Q8TAA9
Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde -0.3578823835148594 0.0 1.0 1.0 1.0 2 Q13555
Asparagine n linked glycosylation 0.27714372688227734 0.0 1.0 1.0 1.0 127 P49755,P53602,P46977,Q9Y3B3,P54727,P24390,Q08379,P04350,Q96JB2,Q9BUN8,O95249,O43731,P61163,P68371,Q96PC5,Q9BUF5,P10619,Q13561,Q13885,Q8IUR0,Q9UJW0,O75935,Q14789,Q9NYU2,Q9BVA1,Q13724,Q9BT22,Q15363,Q92734,Q9Y296,Q13190,Q86YN1,O15027,Q13438
Innate immune system 0.20220218563168163 0.0 1.0 1.0 1.0 304 Q9Y315,P11717,Q5T9A4,P10321,P30519,Q9Y5K8,P49721,P31949,Q9Y487,P04439,O75874,P60900,Q969Q5,P61916,P51812,Q8IV08,Q9NZJ7,O00264,Q9H7Z7,P27105,Q86UT6,P28072,P42785,Q9NQX7,Q07065,P68371,Q14997,P09601,P10619,P07437,O43865,P28070,Q93050,P12956,P78371,P17900,P09960,O94826,P27361,P07602,P10909,P20618,Q9H1C4,Q9BTY2,Q9UQB8