| term overlap setsize score pval |
| Metabolism of folate and pterines 2 9 2.7202960339610778 0.0065223495907089 |
| Glycosphingolipid metabolism 7 16 -2.5188270467886738 0.0117746477716007 |
| Platelet activation signaling and aggregation 10 59 -2.446823750206224 0.0144121296368096 |
| Synthesis of 5 eicosatetraenoic acids 0 1 2.431226529009656 0.0150478031215288 |
| Chylomicron clearance 1 1 -2.412267639329883 0.0158536391209804 |
| Choline catabolism 1 1 -2.4078126293395727 0.0160484151796354 |
| Metabolism of nucleotides 18 51 -2.400389975646392 0.0163776133781088 |
| Ldl clearance 3 13 -2.398953556374325 0.0164419999720826 |
| Scavenging by class b receptors 0 1 2.360155388374763 0.0182672816387685 |
| Tyrosine catabolism 1 1 -2.351266546967484 0.0187096259384798 |
| Pten regulation 10 67 2.332258348209228 0.0196871042912429 |
| Caspase activation via dependence receptors in the absence of ligand 0 1 2.3244996643556832 0.0200987295341574 |
| Keratan sulfate biosynthesis 0 1 2.32003718792817 0.0203388656986529 |
| Keratan sulfate degradation 4 4 -2.313161469317934 0.0207137631277976 |
| Phospholipid metabolism 14 48 2.296255720150025 0.0216612642950884 |
| Ampk inhibits chrebp transcriptional activation activity 0 1 2.2962169131499324 0.021663481968607 |
| Rho gtpases activate rhotekin and rhophilins 0 1 2.290256517308653 0.0220064508814052 |
| Pi3k akt activation 0 1 2.290256517308653 0.0220064508814052 |
| Synthesis of lipoxins lx 1 1 -2.2690514552973795 0.023265196963901 |
| Hydrolysis of lpc 0 1 2.267886286855104 0.0233361383730819 |
| Nectin necl trans heterodimerization 0 1 2.257436813005093 0.0239807936065541 |
| Diseases of carbohydrate metabolism 4 9 -2.252501285791083 0.0242906115557484 |
| Formation of senescence associated heterochromatin foci sahf 6 9 -2.24617740260296 0.0246926470569044 |
| Akt phosphorylates targets in the nucleus 0 1 2.2230586543578355 0.0262118451301516 |
| Tnfr1 mediated ceramide production 0 1 2.2200660900959326 0.0264142816470249 |
| Nrif signals cell death from the nucleus 1 1 -2.2089923060904573 0.0271751760621956 |
| Molecules associated with elastic fibres 1 1 -2.1969544535488903 0.0280236992380462 |
| Fibronectin matrix formation 1 1 -2.1969544535488903 0.0280236992380462 |
| Met interacts with tns proteins 1 1 -2.1969544535488903 0.0280236992380462 |
| Elastic fibre formation 1 1 -2.1969544535488903 0.0280236992380462 |
| Mrna editing c to u conversion 0 1 2.1871152003400067 0.0287341152624831 |
| Carnitine metabolism 3 6 2.1683148455899324 0.0301347396666238 |
| Phase 0 rapid depolarisation 0 1 2.167616538879165 0.0301878743306156 |
| Terminal pathway of complement 1 1 -2.1517375046930183 0.0314180344728445 |
| G alpha q signalling events 7 15 -2.1194308237953834 0.0340540741533896 |
| Glycerophospholipid biosynthesis 6 28 2.118035933918916 0.0341720245436349 |
| Regulation of foxo transcriptional activity by acetylation 1 1 -2.106405532035576 0.0351691411741574 |
| Nucleotide catabolism 4 8 -2.1060628898759983 0.0351988898322401 |
| Abacavir transmembrane transport 0 1 2.0984629130151258 0.0358642727593263 |
| Estrogen stimulated signaling through prkcz 1 1 -2.0927842282362805 0.0363684203488194 |
| Sulfide oxidation to sulfate 0 1 2.092438298413825 0.0363993258328143 |
| Phosphorylation of the apc c 6 12 2.0902495005874626 0.0365953930219453 |
| Synthesis of pc 1 6 2.0848482206043206 0.0370830800405466 |
| Amyloid fiber formation 4 7 -2.0779393561748165 0.0377149450567604 |
| Zinc efflux and compartmentalization by the slc30 family 0 1 2.057763410244935 0.0396128500415962 |
| Zinc transporters 0 1 2.057763410244935 0.0396128500415962 |
| Metal ion slc transporters 0 1 2.057763410244935 0.0396128500415962 |
| Mitotic spindle checkpoint 20 60 2.056876940723948 0.0396980646044382 |
| Scavenging of heme from plasma 1 1 -2.04123897681036 0.0412270792750804 |
| Purine catabolism 4 7 -2.0399370476479683 0.0413565962000714 |
| Myogenesis 1 7 -2.039574694067236 0.0413927046582249 |
| Runx1 and foxp3 control the development of regulatory t lymphocytes tregs 1 1 -2.027572312044126 0.0426039172538894 |
| Runx1 regulates transcription of genes involved in differentiation of keratinocytes 1 1 -2.027572312044126 0.0426039172538894 |
| Runx1 regulates transcription of genes involved in bcr signaling 1 1 -2.027572312044126 0.0426039172538894 |
| Runx1 regulates transcription of genes involved in interleukin signaling 1 1 -2.027572312044126 0.0426039172538894 |
| Runx1 regulates transcription of genes involved in wnt signaling 1 1 -2.027572312044126 0.0426039172538894 |
| Runx2 regulates chondrocyte maturation 1 1 -2.027572312044126 0.0426039172538894 |
| Runx3 regulates immune response and cell migration 1 1 -2.027572312044126 0.0426039172538894 |
| Elevation of cytosolic ca2 levels 1 1 -2.0260532324770906 0.0427593299014423 |
| Neurotoxicity of clostridium toxins 1 1 -2.0230147392747555 0.0430716279213152 |
| Toxicity of botulinum toxin type d botd 1 1 -2.0230147392747555 0.0430716279213152 |
| Glycosaminoglycan metabolism 5 13 -2.021058207313009 0.0432737399554394 |
| Hyaluronan metabolism 2 4 -2.0111906973104534 0.0443053180079253 |
| Hyaluronan uptake and degradation 2 4 -2.0111906973104534 0.0443053180079253 |
| Sodium calcium exchangers 1 1 -2.000212017420582 0.0454773746988717 |
| Apc c cdc20 mediated degradation of cyclin b 5 11 1.998778389172542 0.0456323370383651 |
| Keratan sulfate keratin metabolism 4 5 -1.9984997918129896 0.0456625024854699 |
| Regulation of gene expression in early pancreatic precursor cells 1 1 -1.991084112411454 0.0464716408089431 |
| Effects of pip2 hydrolysis 1 5 -1.972482658622328 0.0485545340260413 |
| 2 ltr circle formation 2 5 -1.9651428803180415 0.0493977028134686 |
| Lipophagy 0 4 1.961689523702056 0.0497986422737568 |
| Conversion from apc c cdc20 to apc c cdh1 in late anaphase 4 9 1.957425118622795 0.0502975076702509 |
| P75ntr recruits signalling complexes 1 1 -1.9545348497749893 0.0506379976119502 |
| Aberrant regulation of mitotic exit in cancer due to rb1 defects 4 10 1.949879740407784 0.0511904543941414 |
| Olfactory signaling pathway 0 1 1.9458438239357203 0.0516735026068997 |
| Glucagon type ligand receptors 0 1 1.9458438239357203 0.0516735026068997 |
| Potassium channels 0 1 1.9458438239357203 0.0516735026068997 |
| Inwardly rectifying k channels 0 1 1.9458438239357203 0.0516735026068997 |
| Prostacyclin signalling through prostacyclin receptor 0 1 1.9458438239357203 0.0516735026068997 |
| Sensory perception of taste 0 1 1.9458438239357203 0.0516735026068997 |
| G protein activation 0 1 1.9458438239357203 0.0516735026068997 |
| Activation of the phototransduction cascade 0 1 1.9458438239357203 0.0516735026068997 |
| Presynaptic function of kainate receptors 0 1 1.9458438239357203 0.0516735026068997 |
| Vitamin b1 thiamin metabolism 0 1 1.9367475167706407 0.0527762142514065 |
| Plasma lipoprotein clearance 3 15 -1.9332697720559304 0.0532029735264301 |
| Pink1 prkn mediated mitophagy 4 8 1.9231103111630516 0.0544661976698679 |
| Mitotic telophase cytokinesis 8 12 1.9147797548168044 0.055520597396987 |
| Signaling by gpcr 9 51 -1.9077087153925785 0.0564288746511869 |
| Mitophagy 6 11 1.9076451476004963 0.0564370957176327 |
| G protein beta gamma signalling 2 5 1.9066831398118045 0.0565616315843524 |
| Downregulation of tgf beta receptor signaling 0 7 1.9035759754362984 0.0569654301696305 |
| Acyl chain remodelling of ps 1 1 -1.8965489119668395 0.0578874987069224 |
| Signaling by notch3 4 8 -1.893607282239902 0.0582771561960453 |
| Signal transduction by l1 4 11 -1.893277814031114 0.058320933967328 |
| N glycan trimming and elongation in the cis golgi 1 1 -1.884324362375558 0.0595211139916618 |
| Ptk6 promotes hif1a stabilization 1 1 -1.8797387114528763 0.0601436969364728 |
| Erbb2 activates ptk6 signaling 1 1 -1.8797387114528763 0.0601436969364728 |
| Condensation of prometaphase chromosomes 5 10 1.8757966521075229 0.0606832078922594 |
| Unwinding of dna 3 10 -1.8597153881845716 0.0629258037247133 |
| Ldl remodeling 0 1 1.8593155587883012 0.0629824228999231 |
| Vldl assembly 0 1 1.8593155587883012 0.0629824228999231 |
| Chylomicron assembly 0 1 1.8593155587883012 0.0629824228999231 |
| Notch3 activation and transmission of signal to the nucleus 3 5 -1.8525392671203045 0.0639484243379269 |
| Heme degradation 1 4 1.8334795724031625 0.066731283692127 |
| Heparan sulfate heparin hs gag metabolism 3 4 -1.831841040082571 0.0669751068514927 |
| A tetrasaccharide linker sequence is required for gag synthesis 1 1 -1.8139299863744809 0.069688505457667 |
| Synthesis of pe 1 3 1.8075963047120676 0.070669353786702 |
| Diseases of metabolism 22 45 -1.8038145011395803 0.0712603917811769 |
| Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 4 12 1.8007910552521065 0.0717358192500419 |
| Apc cdc20 mediated degradation of nek2a 4 12 1.8007910552521065 0.0717358192500419 |
| Dna damage telomere stress induced senescence 9 18 -1.7939137457712433 0.0728269371083656 |
| Mucopolysaccharidoses 3 3 -1.7911769017238162 0.0732649116117722 |
| Synthesis of pa 3 8 1.7857502431905197 0.0741397063047213 |
| Neurofascin interactions 1 1 -1.7817407073112714 0.0747915253081745 |
| Cohesin loading onto chromatin 5 9 1.7807123907259257 0.074959447897372 |
| Chondroitin sulfate biosynthesis 0 1 1.777142501495318 0.075544796875949 |
| Phosphate bond hydrolysis by nudt proteins 1 3 -1.7768591351144143 0.0755914193822766 |
| Egr2 and sox10 mediated initiation of schwann cell myelination 5 6 1.7709772264389854 0.0765644888537147 |
| Fatty acid metabolism 10 60 1.7686669744711492 0.0769494667276988 |
| Beta catenin independent wnt signaling 6 56 1.766123450696607 0.0773751399688893 |
| Regulation of gene expression by hypoxia inducible factor 1 1 -1.7648680633714589 0.0775859422382092 |
| Regulation of pten stability and activity 5 43 1.7614655991477173 0.0781596305550902 |
| Arachidonate production from dag 1 3 -1.7491404107910071 0.0802667514318757 |
| Lgi adam interactions 1 1 -1.7479880951089015 0.0804660888826571 |
| Synaptic adhesion like molecules 1 7 1.742313940800011 0.0814535253565886 |
| Chondroitin sulfate dermatan sulfate metabolism 2 4 -1.7421913958031945 0.0814749590630676 |
| Activated ntrk2 signals through pi3k 1 1 -1.7387779363836957 0.0820738309785347 |
| Sos mediated signalling 1 1 -1.7387779363836957 0.0820738309785347 |
| Signaling by fgfr3 fusions in cancer 1 1 -1.7387779363836957 0.0820738309785347 |
| Activated ntrk3 signals through ras 1 1 -1.7387779363836957 0.0820738309785347 |
| Shc mediated cascade fgfr3 1 1 -1.7387779363836957 0.0820738309785347 |
| Met activates pi3k akt signaling 1 1 -1.7387779363836957 0.0820738309785347 |
| Activated ntrk2 signals through ras 1 1 -1.7387779363836957 0.0820738309785347 |
| Shc related events triggered by igf1r 1 1 -1.7387779363836957 0.0820738309785347 |
| Shc mediated cascade fgfr4 1 1 -1.7387779363836957 0.0820738309785347 |
| Shc mediated cascade fgfr1 1 1 -1.7387779363836957 0.0820738309785347 |
| Shc1 events in erbb4 signaling 1 1 -1.7387779363836957 0.0820738309785347 |
| Neurotransmitter release cycle 3 7 -1.7359183859918776 0.0825782663382903 |
| Acyl chain remodelling of pi 0 1 1.731428880059719 0.0833752993804437 |
| Abacavir metabolism 1 1 -1.7311013183928714 0.0834336952737611 |
| Met receptor recycling 4 4 -1.7252546092079977 0.0844815981540323 |
| Triglyceride biosynthesis 0 1 1.7222821671299604 0.0850184165139005 |
| Tgf beta receptor signaling activates smads 0 9 1.7214189312795902 0.085174831398942 |
| Diseases of mitotic cell cycle 6 13 1.720795792054732 0.0852878862798567 |
| Energy dependent regulation of mtor by lkb1 ampk 1 7 1.7158525131182962 0.086189039979674 |
| Resolution of sister chromatid cohesion 23 66 1.7107282717608048 0.08713128612915 |
| Signaling by mst1 1 1 -1.7096000528404918 0.0873398558775384 |
| Ras processing 0 6 1.7069450038110212 0.0878322749344227 |
| Interferon signaling 15 65 1.6986917197105478 0.0893772844141582 |
| Late endosomal microautophagy 3 10 -1.6983990290339217 0.0894324752432518 |
| Sirt1 negatively regulates rrna expression 4 5 -1.689120054896614 0.0911964253160757 |
| Integration of provirus 2 6 -1.6760442605204884 0.0937295234098021 |
| Fceri mediated mapk activation 3 9 -1.6719039617219975 0.0945432614611603 |
| Plasma lipoprotein assembly remodeling and clearance 3 19 -1.66766997588376 0.0953812587199598 |
| Visual phototransduction 4 11 -1.6562039393343413 0.0976805257650859 |
| Transport of bile salts and organic acids metal ions and amine compounds 2 3 1.6497299905727985 0.0989981733576561 |
| G beta gamma signalling through pi3kgamma 2 3 1.6486640004166109 0.0992164891785598 |
| Mtor signalling 3 13 1.645755960401886 0.0998140126047548 |
| Small interfering rna sirna biogenesis 2 4 1.6447940013429552 0.100012299653764 |
| Gastrin creb signalling pathway via pkc and mapk 5 7 -1.63956043624879 0.1010965949539079 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 2 7 1.6387734861321677 0.1012604429901122 |
| Cellular hexose transport 1 1 -1.637358153186884 0.1015556565577493 |
| Rho gtpases activate formins 15 64 1.6295702563521397 0.1031923549704594 |
| Establishment of sister chromatid cohesion 3 7 1.621879438820702 0.1048291648389394 |
| Activation of nima kinases nek9 nek6 nek7 2 5 1.6192247638102732 0.1053989116596099 |
| Cation coupled chloride cotransporters 0 1 1.6185662532857723 0.1055406209695686 |
| Phase i functionalization of compounds 7 15 1.6177184475349264 0.1057232885325101 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 0 3 1.6157154974242929 0.1061558387634775 |
| Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 1 3 1.610737967036542 0.1072368467414661 |
| Dap12 signaling 2 4 -1.6094583176540136 0.1075161622901257 |
| Peptide ligand binding receptors 3 7 -1.6089538495979514 0.1076264333013532 |
| Class a 1 rhodopsin like receptors 3 7 -1.6089538495979514 0.1076264333013532 |
| Pentose phosphate pathway 6 8 -1.606014451518696 0.1082707347308842 |
| Metabolism of porphyrins 1 9 1.604553347221212 0.1085921353519818 |
| Diseases associated with glycosaminoglycan metabolism 2 3 -1.6026192734836733 0.1090187359326364 |
| O linked glycosylation 1 4 1.599327285978914 0.1097478997326333 |
| Disorders of transmembrane transporters 13 74 1.5968943349853435 0.1102892627954377 |
| Rho gtpases activate ktn1 0 7 1.5954080440984792 0.1106210183570652 |
| Transport of inorganic cations anions and amino acids oligopeptides 2 9 1.5907444000439568 0.1116671102827768 |
| Inhibition of dna recombination at telomere 4 12 -1.582729303308117 0.1134831763261603 |
| Slc mediated transmembrane transport 5 19 1.580897277309238 0.1139015269740362 |
| Regulation of fzd by ubiquitination 1 1 -1.5804462830617303 0.1140046993978431 |
| Formyl peptide receptors bind formyl peptides and many other ligands 2 3 -1.5791946273938395 0.1142914219118211 |
| Antimicrobial peptides 2 3 -1.5740764637920863 0.1154697730849525 |
| Synthesis of pg 1 3 1.5714477224717829 0.1160786883961835 |
| Ovarian tumor domain proteases 0 9 1.569311649811165 0.1165753390968302 |
| Nuclear signaling by erbb4 2 4 -1.554597420540346 0.1200419785007045 |
| Transcriptional regulation by the ap 2 tfap2 family of transcription factors 4 7 -1.5516412761699856 0.1207480810119947 |
| Mapk6 mapk4 signaling 5 51 1.5469373821111403 0.1218783457814052 |
| Ion transport by p type atpases 1 11 -1.5465696355174732 0.1219670563953658 |
| Mitochondrial protein import 5 33 1.5237757373745786 0.127564742428365 |
| Lysine catabolism 1 7 -1.5165835503014502 0.1293718611423646 |
| Regulation of commissural axon pathfinding by slit and robo 1 1 -1.5127596935967902 0.1303407105362333 |
| Branched chain amino acid catabolism 3 15 1.511787256504441 0.1305879923303647 |
| Shc1 events in erbb2 signaling 4 4 -1.5088156155993773 0.1313459090244499 |
| Eph ephrin mediated repulsion of cells 3 14 -1.5034330459524294 0.1327274103409756 |
| Josephin domain dubs 2 3 -1.5020872705447463 0.1330745719254624 |
| Cell extracellular matrix interactions 4 9 -1.4976896664573125 0.1342138978717884 |
| Trail signaling 0 1 1.496580342659933 0.1345024881665804 |
| Advanced glycosylation endproduct receptor signaling 4 9 -1.494625698907871 0.1350121553229886 |
| Negative regulation of mapk pathway 4 12 1.4908213280538087 0.1360084106265882 |
| Sialic acid metabolism 2 5 -1.488801929771527 0.1365395340211477 |
| Switching of origins to a post replicative state 7 62 1.4868680575840882 0.1370496621559858 |
| Apc c mediated degradation of cell cycle proteins 7 58 1.4862611767945089 0.1372100514366414 |
| Protein repair 0 1 1.4828713417406714 0.1381085968758275 |
| Egfr transactivation by gastrin 3 3 -1.4815262985492377 0.1384663823134477 |
| Metabolism of water soluble vitamins and cofactors 5 39 1.481369748455375 0.1385080714496755 |
| Gpcr ligand binding 3 9 -1.4703072809599878 0.1414785499939213 |
| Assembly of active lpl and lipc lipase complexes 0 1 1.463077769790939 0.1434460999561491 |
| Gaba receptor activation 1 4 1.4618345980184906 0.1437865406543763 |
| Adp signalling through p2y purinoceptor 12 1 4 1.4618345980184906 0.1437865406543763 |
| Gaba b receptor activation 1 4 1.4618345980184906 0.1437865406543763 |
| Metabolism of fat soluble vitamins 2 5 -1.4617383154703958 0.1438129333133753 |
| Fceri mediated ca 2 mobilization 3 7 -1.4523485125812043 0.1464047247708637 |
| Sphingolipid metabolism 8 26 -1.4506526534968311 0.1468766056290213 |
| Phenylalanine and tyrosine metabolism 2 4 -1.450435209307807 0.1469371945477129 |
| Signaling by pdgf 4 8 -1.4442549289115978 0.148667278884981 |
| Downstream signal transduction 4 8 -1.4442549289115978 0.148667278884981 |
| Immunoregulatory interactions between a lymphoid and a non lymphoid cell 2 5 -1.442704557250704 0.1491037149243697 |
| Nr1h2 and nr1h3 mediated signaling 2 9 1.434379726700107 0.1514639298135325 |
| Defective lfng causes scdo3 1 1 -1.4343564194649274 0.1514705774847331 |
| Notch2 intracellular domain regulates transcription 1 1 -1.4343564194649274 0.1514705774847331 |
| Maturation of sars cov 2 nucleoprotein 2 4 1.4284557872052326 0.1531607117294955 |
| Regulation of runx1 expression and activity 1 5 1.4244285665166467 0.1543224497615016 |
| Diseases of glycosylation 9 20 -1.42212662299166 0.1549894953378368 |
| Diseases associated with glycosylation precursor biosynthesis 3 9 -1.4186303477865 0.1560068134058525 |
| Defects of contact activation system cas and kallikrein kinin system kks 0 1 1.4144062592683129 0.1572426533377853 |
| Gamma carboxylation transport and amino terminal cleavage of proteins 0 1 1.4144062592683129 0.1572426533377853 |
| Defective factor ix causes hemophilia b 0 1 1.4144062592683129 0.1572426533377853 |
| Scavenging by class a receptors 1 3 -1.4109646127101176 0.1582550486058909 |
| Signaling by erbb4 0 9 1.4103636277450404 0.1584323395171649 |
| Apoptosis induced dna fragmentation 5 10 -1.4047519571747804 0.1600950497224693 |
| Signaling by mras complex mutants 0 3 1.396051211388362 0.1626990742017215 |
| Clathrin mediated endocytosis 17 59 -1.395321827198151 0.162918812841998 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 2 12 1.3909291400691333 0.1642469153519186 |
| Chaperone mediated autophagy 1 6 -1.3896585946304607 0.1646325736571552 |
| Synthesis of prostaglandins pg and thromboxanes tx 2 4 -1.3895559414147358 0.1646637625158569 |
| Fatty acyl coa biosynthesis 4 18 -1.37759937776701 0.1683270131700727 |
| Signaling by bmp 0 1 1.3764447413420282 0.1686839841931817 |
| Vegfr2 mediated vascular permeability 1 11 -1.3641311523041035 0.1725262917639862 |
| G2 m dna replication checkpoint 2 4 1.3614557149904227 0.1733697193588201 |
| Dap12 interactions 1 5 -1.3609833098480657 0.173518963925082 |
| Linoleic acid la metabolism 1 1 -1.3606904424084296 0.1736115362500805 |
| Early phase of hiv life cycle 2 8 -1.3590036778967172 0.174145423256097 |
| Caspase activation via extrinsic apoptotic signalling pathway 1 5 1.3585809994613254 0.1742793994375442 |
| Resolution of d loop structures through synthesis dependent strand annealing sdsa 4 12 1.3551257745952616 0.1753774880552556 |
| Resolution of d loop structures 4 12 1.3551257745952616 0.1753774880552556 |
| Interconversion of nucleotide di and triphosphates 7 21 -1.3550113995318314 0.1754139251115973 |
| Mecp2 regulates neuronal receptors and channels 3 6 1.3522066433096305 0.1763092190924693 |
| E2f enabled inhibition of pre replication complex formation 3 6 1.3515539354992014 0.1765180548461626 |
| Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3 2 5 -1.349798509338196 0.1770806231509831 |
| Base excision repair ap site formation 2 5 -1.3409112191078467 0.179949279214969 |
| Interleukin 2 signaling 1 1 -1.3407710170601412 0.1799948089566683 |
| Signalling to erks 5 10 -1.336434371494896 0.1814073381043066 |
| Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 4 9 -1.3306698445948182 0.1832976695821617 |
| Traf6 mediated nf kb activation 2 8 -1.3062314468322376 0.1914738617794942 |
| Androgen biosynthesis 0 1 1.3052746064449905 0.1917993576529517 |
| Protein localization 13 74 1.303115047358312 0.1925354871597728 |
| Phosphorylation of emi1 1 3 1.3030084938049526 0.1925718617829452 |
| Bbsome mediated cargo targeting to cilium 1 7 -1.300247877786919 0.1935160259242407 |
| G1 s specific transcription 1 14 1.299089085977256 0.1939133581623182 |
| Antiviral mechanism by ifn stimulated genes 11 51 1.2980323414614292 0.1942762217475779 |
| Metabolism of cofactors 1 6 1.2936370924863638 0.1957908038582039 |
| Mtorc1 mediated signalling 3 8 1.2872986508494657 0.1979902136255678 |
| Synthesis of glycosylphosphatidylinositol gpi 0 1 1.2675489351389395 0.204959077704858 |
| Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 4 15 1.2648413197423172 0.205928216057337 |
| Chl1 interactions 1 3 -1.2645939399354875 0.2060169265470015 |
| O linked glycosylation of mucins 1 3 1.2642413497611855 0.206143413487202 |
| Ephrin signaling 2 5 -1.2572039761203495 0.2086797838940544 |
| Tysnd1 cleaves peroxisomal proteins 1 6 1.2567412152767032 0.2088473585541042 |
| Wnt5a dependent internalization of fzd4 3 9 -1.2534994954020486 0.210023982600648 |
| Dopamine clearance from the synaptic cleft 0 1 1.2509835994627696 0.2109404611004772 |
| Signaling by wnt in cancer 4 9 1.2507849654847674 0.2110129415402206 |
| Orc1 removal from chromatin 4 53 1.248767906409264 0.2117499755217342 |
| Activation of ampk downstream of nmdars 1 8 1.247712822810772 0.2121362437238687 |
| Ptk6 regulates rtks and their effectors akt1 and dok1 0 1 1.2434613090357909 0.2136978900392603 |
| Flt3 signaling by cbl mutants 0 1 1.2434613090357909 0.2136978900392603 |
| Downregulation of smad2 3 smad4 transcriptional activity 0 7 1.2416416366288816 0.2143688123901148 |
| Abc family proteins mediated transport 8 54 1.241286068180684 0.214500089466064 |
| Erythropoietin activates stat5 0 1 1.2404537323696705 0.2148076172958828 |
| Cd22 mediated bcr regulation 0 1 1.2404537323696705 0.2148076172958828 |
| Dectin 2 family 0 1 1.2404537323696705 0.2148076172958828 |
| Erythropoietin activates phosphoinositide 3 kinase pi3k 0 1 1.2404537323696705 0.2148076172958828 |
| Formation of incision complex in gg ner 7 14 -1.238169536463463 0.2156532046171313 |
| Miscellaneous transport and binding events 3 8 -1.236184519587793 0.2163899835780145 |
| Glutamate neurotransmitter release cycle 2 3 -1.2356764586868954 0.2165788514895736 |
| Transcriptional regulation by ventx 7 17 1.23487238315158 0.2168780030775741 |
| Aryl hydrocarbon receptor signalling 1 3 1.2318101867889235 0.2180199971405532 |
| Metabolism of polyamines 4 40 1.228478782696238 0.2192672894166167 |
| Recognition and association of dna glycosylase with site containing an affected purine 2 4 -1.2271377229509293 0.2197708316396154 |
| Ecm proteoglycans 2 3 -1.2271108363979344 0.21978093550358 |
| Regulation of mecp2 expression and activity 5 13 1.2247194444268548 0.2206809453389908 |
| Other interleukin signaling 0 5 1.2243886081115083 0.2208056647005198 |
| Synthesis of bile acids and bile salts via 24 hydroxycholesterol 1 1 -1.2201550338629383 0.2224061092376017 |
| Sphingolipid de novo biosynthesis 5 10 1.21104455527249 0.2258783290804478 |
| Tak1 activates nfkb by phosphorylation and activation of ikks complex 2 7 -1.2110206070071723 0.2258875070370085 |
| Surfactant metabolism 0 1 1.2104221484992193 0.2261169473044182 |
| Syndecan interactions 2 5 -1.2095097805743371 0.2264670558304882 |
| Synthesis of ketone bodies 0 3 1.2086071096195656 0.2268138237016974 |
| Biosynthesis of epa derived spms 1 1 -1.2064734201113518 0.2276350017161703 |
| Map2k and mapk activation 4 13 1.205667157232995 0.2279458533479763 |
| Adherens junctions interactions 0 7 1.204491729231403 0.2283995768826385 |
| Apoptotic cleavage of cell adhesion proteins 2 6 1.202489588515842 0.2291738975480168 |
| Repression of wnt target genes 2 4 1.201239540404987 0.2296582954976542 |
| Uch proteinases 5 49 1.1979142161345768 0.2309504147484278 |
| Alpha oxidation of phytanate 1 5 1.1976603326080106 0.2310492779484141 |
| Transcriptional regulation by runx1 10 75 1.1960098339353529 0.231692721521223 |
| Intracellular signaling by second messengers 12 89 1.1954737875713235 0.2319019715968719 |
| Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 7 49 1.1930777440249722 0.2328389269015185 |
| Vitamin b2 riboflavin metabolism 0 1 1.1924441040924851 0.2330871555290552 |
| Ca2 pathway 2 7 1.185463350161342 0.235834297062071 |
| Beta oxidation of very long chain fatty acids 0 4 1.1844206946769693 0.2362465722076989 |
| Role of phospholipids in phagocytosis 0 5 1.178471329549625 0.2386087557094649 |
| Glycogen storage diseases 1 3 -1.1694387626651528 0.2422269001055992 |
| Nucleotide biosynthesis 8 13 -1.16913741512063 0.2423482715416396 |
| Ctla4 inhibitory signaling 4 8 1.1641178789366338 0.2443762440483015 |
| Mastl facilitates mitotic progression 2 5 1.1626615143667436 0.2449668620648104 |
| Formation of atp by chemiosmotic coupling 5 9 -1.1593303840464064 0.2463215412913288 |
| Stat3 nuclear events downstream of alk signaling 1 4 1.158672055086873 0.2465898857597133 |
| Deactivation of the beta catenin transactivating complex 7 10 1.1503166883023752 0.2500134598106216 |
| Cytoprotection by hmox1 7 68 1.1478095813982636 0.2510471810525878 |
| Ret signaling 5 6 -1.143692222200312 0.2527513001013419 |
| Rsk activation 2 4 -1.1416522954022648 0.2535985773385287 |
| Glutathione synthesis and recycling 4 6 -1.1415336326800782 0.2536479243201535 |
| Defective intrinsic pathway for apoptosis 13 16 -1.140123616800097 0.2542348040694948 |
| Netrin 1 signaling 1 12 -1.136274483019116 0.2558417065845075 |
| Interleukin 2 family signaling 3 4 -1.1306350361451991 0.258208734602392 |
| Mapk1 erk2 activation 2 4 -1.129579528329779 0.2586534411838912 |
| Gpvi mediated activation cascade 1 6 -1.1294109388429343 0.2587245204440278 |
| Dna methylation 2 5 -1.128568001715294 0.2590801154348616 |
| Cyclin a b1 b2 associated events during g2 m transition 6 12 1.1269682900900326 0.2597558881765986 |
| Displacement of dna glycosylase by apex1 1 3 1.1263801544224117 0.2600046432815441 |
| Cs ds degradation 2 2 -1.1259913967668145 0.2601691608896481 |
| Met promotes cell motility 4 7 -1.1258741487180923 0.2602187930048592 |
| Cytosolic iron sulfur cluster assembly 1 7 -1.1223667257548338 0.261706546071959 |
| Cargo concentration in the er 4 14 -1.1179509732618431 0.2635879329197608 |
| Adrenaline noradrenaline inhibits insulin secretion 1 3 1.1147815517201152 0.2649440438955297 |
| Sars cov infections 9 64 -1.1130924299474492 0.2656687345482653 |
| Serotonin neurotransmitter release cycle 0 1 1.1119807128913874 0.2661464431107683 |
| Norepinephrine neurotransmitter release cycle 0 1 1.1119807128913874 0.2661464431107683 |
| Acetylcholine neurotransmitter release cycle 0 1 1.1119807128913874 0.2661464431107683 |
| The role of gtse1 in g2 m progression after g2 checkpoint 6 51 1.1070042037081052 0.2682921108541602 |
| Mecp2 regulates transcription factors 0 1 1.1016089809271783 0.2706317022114164 |
| Sulfur amino acid metabolism 1 9 1.098544699281902 0.271966710327038 |
| Signaling by hedgehog 7 60 1.096068516847782 0.273048791107966 |
| Endosomal vacuolar pathway 1 3 1.0908697990598963 0.2753301778629373 |
| Tight junction interactions 1 1 -1.0886031485869432 0.2763289277205287 |
| Signal regulatory protein family interactions 2 3 -1.082339461217396 0.2791017176559678 |
| Transcriptional regulation by mecp2 5 16 1.081381564978172 0.2795274185748229 |
| Ethanol oxidation 2 3 -1.081023585486888 0.2796866223269478 |
| Raf activation 3 10 1.0796605157201404 0.2802933826169638 |
| Chrebp activates metabolic gene expression 2 5 1.0780334816041608 0.2810188146012553 |
| Regulation of hmox1 expression and activity 4 48 1.0749892125091542 0.282379558053438 |
| Amino acids regulate mtorc1 4 11 1.0736109113910717 0.2829971051244189 |
| Assembly of the hiv virion 2 3 -1.0725227244033853 0.2834853127283714 |
| Mitochondrial iron sulfur cluster biogenesis 3 4 -1.069525020384847 0.2848331608049625 |
| Cdc6 association with the orc origin complex 2 5 1.064573805670775 0.2870688387367508 |
| Metabolic disorders of biological oxidation enzymes 4 6 -1.0631441826550128 0.2877165705498468 |
| Downregulation of erbb4 signaling 0 2 1.060999415859712 0.2886901666380641 |
| Downstream signaling events of b cell receptor bcr 5 46 1.060497814879721 0.2889181835449492 |
| Ripk1 mediated regulated necrosis 0 13 1.0576754954199945 0.2902034106864053 |
| Met activates rap1 and rac1 3 5 -1.053543678559167 0.2920918866904061 |
| Defects in cobalamin b12 metabolism 1 3 1.0515837891514537 0.2929905485045929 |
| Regulation of pten localization 0 2 1.0476473248036575 0.2948011249108235 |
| Autophagy 7 51 1.0471299059628878 0.2950396679796316 |
| Selective autophagy 5 32 1.0464181441568523 0.2953680192668726 |
| Rho gtpases activate wasps and waves 2 21 1.0386731605248138 0.2989567676662794 |
| Signaling by the b cell receptor bcr 5 51 1.0363108651346449 0.3000571388868003 |
| Glutathione conjugation 7 13 -1.0317546795853507 0.3021870549908763 |
| Cdt1 association with the cdc6 orc origin complex 4 42 1.0287107862513434 0.303615599824151 |
| Signaling by type 1 insulin like growth factor 1 receptor igf1r 1 5 1.027837553128241 0.304026248202879 |
| Egfr downregulation 7 11 -1.0268665013419602 0.3044833299969802 |
| Cargo recognition for clathrin mediated endocytosis 12 35 -1.0245448898852862 0.305577979375794 |
| Signaling by pdgfr in disease 3 5 -1.0231521903251142 0.30623589389112 |
| Calcineurin activates nfat 1 1 -1.0228073085083034 0.3063989617884486 |
| Pcp ce pathway 4 50 1.0219662449522169 0.306796876829273 |
| Regulation of ifna signaling 2 5 -1.0200692340345296 0.3076956267013502 |
| Pka mediated phosphorylation of creb 4 4 -1.0191837908112886 0.3081157204397724 |
| Creb1 phosphorylation through the activation of adenylate cyclase 4 4 -1.0191837908112886 0.3081157204397724 |
| Pka activation in glucagon signalling 4 4 -1.0191837908112886 0.3081157204397724 |
| Apobec3g mediated resistance to hiv 1 infection 1 3 -1.0172975430634106 0.309011905059922 |
| Competing endogenous rnas cernas regulate pten translation 1 2 1.016538265875218 0.3093731349421422 |
| Regulation of pten mrna translation 1 2 1.016538265875218 0.3093731349421422 |
| Negative regulation of met activity 6 8 -1.0159851908997506 0.3096364386817707 |
| Slc transporter disorders 7 32 1.0123987261793126 0.3113474471737447 |
| Formation of the beta catenin tcf transactivating complex 4 12 -1.009158578985132 0.3128985879945873 |
| Diseases of dna repair 5 14 1.0065909442145893 0.3141313880334748 |
| Piwi interacting rna pirna biogenesis 3 11 1.0064564156041451 0.3141960672927006 |
| Processing of capped intronless pre mrna 5 19 -1.0034949222048937 0.3156221256876592 |
| Gluconeogenesis 13 20 -1.000168431097817 0.3172290039378493 |
| Pregnenolone biosynthesis 2 3 -1.000013241845487 0.3173040996274499 |
| Constitutive signaling by akt1 e17k in cancer 2 4 0.99935713749794 0.3176217156734593 |
| Mrna decay by 5 to 3 exoribonuclease 1 9 0.9954654366880028 0.3195099464518334 |
| Metabolism of vitamins and cofactors 9 49 0.9948720676621984 0.3197984896283017 |
| Vitamin d calciferol metabolism 1 3 0.9906708726985236 0.3218463182866113 |
| Beta oxidation of butanoyl coa to acetyl coa 2 4 -0.9905935532577836 0.3218840868831492 |
| Bmal1 clock npas2 activates circadian gene expression 1 4 0.9891676219255264 0.3225811369935076 |
| Abc transporter disorders 4 42 0.9872273459698464 0.3235311987574634 |
| Defective cftr causes cystic fibrosis 4 42 0.9872273459698464 0.3235311987574634 |
| Ptk6 regulates rho gtpases ras gtpase and map kinases 0 5 0.9845320551730838 0.3248539784468272 |
| Regulation of ifng signaling 2 4 -0.984502430609986 0.3248685369523985 |
| Transcriptional regulation of white adipocyte differentiation 7 17 0.9839376556318872 0.3251461675607714 |
| Translation of replicase and assembly of the replication transcription complex 1 5 -0.9818929270906864 0.3261526006089621 |
| Hs gag degradation 2 2 -0.9813047357560636 0.3264424880774248 |
| Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 2 3 -0.9787476613755732 0.3277046761071913 |
| Rho gtpases activate nadph oxidases 2 7 -0.9752168207645064 0.3294527201098753 |
| Caspase activation via death receptors in the presence of ligand 1 4 0.974033196121784 0.330040056916423 |
| Regulation by c flip 1 4 0.974033196121784 0.330040056916423 |
| Methionine salvage pathway 0 4 0.9710458011141124 0.3315254714222244 |
| Peroxisomal lipid metabolism 2 12 0.9698157627403904 0.3321383343722903 |
| Auf1 hnrnp d0 binds and destabilizes mrna 4 42 0.9694365350148728 0.3323274309913191 |
| Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 6 8 -0.9651078296499884 0.3344908056945719 |
| Pyruvate metabolism 3 17 0.9637185908495628 0.3351870311041314 |
| Prolonged erk activation events 3 6 -0.9619217265765766 0.3360889239011406 |
| C type lectin receptors clrs 4 58 0.9608945033259008 0.3366052148339999 |
| Protein protein interactions at synapses 2 16 0.9598736236945572 0.3371188225561337 |
| Vitamin c ascorbate metabolism 2 3 -0.957748972619954 0.3381893555699022 |
| Nrage signals death through jnk 5 10 -0.9573245215640525 0.338403482085901 |
| Signaling by ctnnb1 phospho site mutants 2 7 0.9559360196188093 0.33910455970766 |
| Beta catenin phosphorylation cascade 2 7 0.9559360196188093 0.33910455970766 |
| Disassembly of the destruction complex and recruitment of axin to the membrane 2 7 0.9559360196188093 0.33910455970766 |
| Defects in vitamin and cofactor metabolism 4 10 0.954478528811726 0.3398414726656886 |
| Runx3 regulates p14 arf 2 3 -0.9536083691179016 0.3402819178263301 |
| Transport of fatty acids 1 1 -0.9517666038689336 0.3412153624835485 |
| Purine ribonucleoside monophosphate biosynthesis 6 10 -0.9478009650755028 0.343230789143182 |
| Signaling by csf3 g csf 5 10 -0.9476733020022668 0.3432957964946679 |
| Dna damage reversal 1 4 0.9454913602833108 0.3444080795938777 |
| Sema4d mediated inhibition of cell attachment and migration 0 2 0.9453143123268838 0.3444984336601595 |
| Ra biosynthesis pathway 1 3 0.9447961399097964 0.3447629629533186 |
| The canonical retinoid cycle in rods twilight vision 0 1 0.9437641015031404 0.3452902090048155 |
| Antigen processing ubiquitination proteasome degradation 11 97 0.942477214998562 0.3459483711810482 |
| Transport of nucleotide sugars 0 1 0.942324776056086 0.3460263871056748 |
| Hedgehog ligand biogenesis 4 40 0.9415708605867484 0.3464123943166435 |
| Synthesis of pyrophosphates in the cytosol 0 1 0.940885915449841 0.3467633261328831 |
| Rhof gtpase cycle 5 22 -0.9359216997011608 0.3493135037251829 |
| Defective ripk1 mediated regulated necrosis 0 3 0.9356268803361883 0.3494653296651129 |
| Tnfr1 induced proapoptotic signaling 0 3 0.9356268803361883 0.3494653296651129 |
| Retrograde transport at the trans golgi network 2 19 0.9320535522871316 0.3513088504119017 |
| Intraflagellar transport 3 13 0.931923937697058 0.3513758356650016 |
| Maturation of sars cov 2 spike protein 3 11 -0.928671951931408 0.3530591207125373 |
| Tcr signaling 4 52 0.9279749645211388 0.3534205562734116 |
| Ubiquinol biosynthesis 1 2 -0.9234680681645656 0.3557633335846624 |
| Telomere c strand synthesis initiation 2 5 -0.9232146835995249 0.3558953382616052 |
| Runx1 regulates transcription of genes involved in differentiation of hscs 4 44 0.9195577048242238 0.3578039375936699 |
| Interleukin 3 interleukin 5 and gm csf signaling 7 11 -0.9183279734166088 0.3584471864823506 |
| Rrna processing in the mitochondrion 2 6 0.9182475280569644 0.3584892912357857 |
| Signaling by vegf 4 36 0.9160871520017224 0.3596211859398646 |
| Oncogene induced senescence 3 8 0.91540444376278 0.3599793463838556 |
| Rna polymerase iii chain elongation 2 7 -0.913345322449952 0.3610609526823505 |
| Rna polymerase iii transcription initiation from type 3 promoter 2 7 -0.913345322449952 0.3610609526823505 |
| Cytochrome p450 arranged by substrate type 1 3 0.9040225276453948 0.3659834561393462 |
| Tnfr2 non canonical nf kb pathway 4 44 0.8981819482252862 0.3690885556587344 |
| Processing of intronless pre mrnas 4 17 -0.8977764939628345 0.3693047187942195 |
| Cellular response to heat stress 17 60 0.8976816071869038 0.3693553179186124 |
| Cell cell junction organization 0 8 0.8973621173065516 0.369525720114308 |
| N glycan antennae elongation in the medial trans golgi 1 2 -0.8931696738663423 0.3717663156932884 |
| Reactions specific to the complex n glycan synthesis pathway 1 2 -0.8931696738663423 0.3717663156932884 |
| Mrna editing 0 2 0.8907946152240664 0.3730393644950842 |
| Rho gtpases activate pkns 6 20 -0.8880910546245151 0.3744917740659816 |
| Pre notch processing in golgi 1 3 -0.8872835195071359 0.3749262761864536 |
| Synthesis of dolichyl phosphate 1 2 0.8794218602755709 0.3791725836643755 |
| Tfap2 ap 2 family regulates transcription of growth factors and their receptors 2 3 -0.8793940895382832 0.3791876356859331 |
| Non integrin membrane ecm interactions 2 6 -0.8786408835465707 0.3795960211621101 |
| Complement cascade 2 2 -0.8772933658767724 0.3803273146809356 |
| Diseases of programmed cell death 11 30 -0.8762264578647514 0.3809069358310433 |
| Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 2 3 -0.8759691203993498 0.3810468212004325 |
| Gaba synthesis release reuptake and degradation 1 3 -0.8751248098282933 0.3815059991379876 |
| Gene silencing by rna 16 49 0.874748270181486 0.3817108895000274 |
| Sumoylation of sumoylation proteins 9 27 0.8746021435503877 0.381790421055769 |
| Sumoylation of ubiquitinylation proteins 9 27 0.8746021435503877 0.381790421055769 |
| Fceri mediated nf kb activation 4 47 0.8717340113203113 0.3833535012330973 |
| Dectin 1 mediated noncanonical nf kb signaling 4 44 0.8683912325342918 0.3851801928738392 |
| Regulated necrosis 1 21 0.868333058508819 0.385212029621099 |
| Interleukin 1 processing 1 1 -0.8657375034638035 0.386634128511808 |
| Rna polymerase ii transcription termination 20 48 -0.8639432923964506 0.3876190430204145 |
| Proton coupled monocarboxylate transport 1 2 0.861511526431445 0.3889563756040683 |
| Signalling to ras 2 4 -0.8606456948952697 0.389433210743292 |
| Processing of smdt1 3 11 -0.8603123344778607 0.3896168954648296 |
| Acetylcholine regulates insulin secretion 2 2 -0.8598246550697312 0.3898857063158831 |
| Acyl chain remodelling of pe 1 1 -0.8585221557304165 0.390604201803314 |
| Potential therapeutics for sars 6 41 -0.8550361495350928 0.3925311354951821 |
| Recognition of dna damage by pcna containing replication complex 4 20 0.8529437570799349 0.3936904945395802 |
| Lysosome vesicle biogenesis 3 14 -0.8527888590457443 0.393776403250702 |
| Formation of xylulose 5 phosphate 2 3 -0.85073290061409 0.3949177425880519 |
| Budding and maturation of hiv virion 0 11 0.8502282952939306 0.3951981732781044 |
| Regulation of mrna stability by proteins that bind au rich elements 5 67 0.8501593415717799 0.395236503147383 |
| Clec7a dectin 1 signaling 4 53 0.850050693991656 0.3952969025256219 |
| Signaling by moderate kinase activity braf mutants 4 13 0.8462830082906377 0.3973948845002533 |
| Trna modification in the mitochondrion 2 7 0.8459281308550335 0.3975928383272427 |
| Antigen processing cross presentation 4 51 0.8453936653969444 0.3978910801282653 |
| Synthesis of active ubiquitin roles of e1 and e2 enzymes 3 10 -0.8433188395875345 0.399050149083668 |
| Platelet sensitization by ldl 2 6 0.8412355060840916 0.4002160130726544 |
| Rhoj gtpase cycle 6 26 -0.8401312585173434 0.4008347955522362 |
| Sumoylation of dna replication proteins 10 35 0.8399232751137752 0.4009514066011217 |
| Signaling by erbb2 ecd mutants 3 6 -0.838265847959165 0.4018814121419645 |
| Signaling by erbb2 in cancer 3 6 -0.838265847959165 0.4018814121419645 |
| Amino acid transport across the plasma membrane 0 3 0.8374740042872575 0.4023261831768465 |
| Calnexin calreticulin cycle 0 7 0.8334687424348795 0.4045804193673536 |
| E2f mediated regulation of dna replication 5 12 0.8322834794284045 0.4052489533949617 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 3 11 0.8322458502402043 0.4052701885155465 |
| Noncanonical activation of notch3 1 2 -0.8294386377317282 0.4068562456227056 |
| Diseases associated with n glycosylation of proteins 3 6 -0.8258534140224564 0.4088872498828331 |
| Hur elavl1 binds and stabilizes mrna 4 7 -0.8245362126156744 0.4096349485181554 |
| Endosomal sorting complex required for transport escrt 6 12 -0.8243849089585379 0.4097208868382582 |
| Synthesis of gdp mannose 1 2 -0.8182579121656778 0.4132099330911774 |
| Interleukin 1 signaling 4 49 0.8151412278935972 0.4149914748074159 |
| Signaling by erythropoietin 2 4 -0.8142301863782457 0.4155130955110779 |
| Rhot1 gtpase cycle 1 1 -0.8140805917331057 0.4155987835647354 |
| Signaling by alk 1 5 0.8125963855993001 0.4164495045313421 |
| Mecp2 regulates transcription of neuronal ligands 1 3 0.8124207095393808 0.416550266935098 |
| Fcgr3a mediated il10 synthesis 7 9 -0.8121144172795309 0.4167259811844599 |
| Signaling by met 8 19 -0.8119669398243804 0.4168106018857598 |
| Erythropoietin activates ras 2 3 -0.8097615134324981 0.41807725622538 |
| Vegfr2 mediated cell proliferation 2 5 -0.8092770576113828 0.4183557996999734 |
| Interleukin 1 family signaling 4 52 0.8084210487172218 0.4188482389032453 |
| Rab geranylgeranylation 8 20 -0.8073989529288871 0.4194366700019032 |
| Regulation of tp53 activity 24 58 0.8049038223684768 0.4208751824870955 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 3 3 -0.8042654057289879 0.4212437122775867 |
| Hedgehog off state 6 53 0.8035419974394485 0.4216615327454407 |
| Creatine metabolism 0 3 0.802436603875933 0.4223004464754178 |
| Nuclear pore complex npc disassembly 10 30 0.7998396331803033 0.4238037169527866 |
| Mapk family signaling cascades 12 96 0.7965626045594332 0.4257051029176573 |
| Defects in biotin btn metabolism 2 7 0.7936458707309039 0.4274016203505311 |
| Glycogen breakdown glycogenolysis 1 6 -0.7913404749114095 0.4287453354422901 |
| Signaling by cytosolic fgfr1 fusion mutants 3 9 -0.7910502987231798 0.428914640448728 |
| Runx2 regulates bone development 2 5 -0.7880055149318382 0.4306934800426525 |
| L1cam interactions 10 43 -0.7873146718713826 0.4310976829941253 |
| Activated notch1 transmits signal to the nucleus 2 3 -0.7864280693618747 0.4316167443578562 |
| Beta oxidation of hexanoyl coa to butanoyl coa 3 5 -0.780422158434626 0.4351424293842942 |
| Costimulation by the cd28 family 6 15 0.7787387092044507 0.4361336487378267 |
| Prc2 methylates histones and dna 3 7 -0.7755728429155818 0.4380012402866384 |
| Biological oxidations 9 46 0.7752490076965767 0.4381925344560424 |
| Hdr through homologous recombination hrr 7 30 0.7752105000663649 0.438215284668193 |
| Runx2 regulates osteoblast differentiation 2 4 -0.7723290734369506 0.4399195501168873 |
| P75ntr regulates axonogenesis 0 3 0.7667685347250673 0.4432191474318265 |
| Robo receptors bind akap5 3 3 -0.7665480122145885 0.4433502953680772 |
| Dna replication pre initiation 7 67 0.7659878518625757 0.4436835305376774 |
| Signaling by tgfb family members 9 22 0.7651578212178765 0.4441775724581693 |
| Metabolism of carbohydrates 28 98 -0.7646454075961566 0.4444827224880088 |
| Rna polymerase iii transcription termination 2 8 -0.7632853300522223 0.4452932490131986 |
| Interleukin 37 signaling 1 3 -0.7622647374175596 0.4459020153466033 |
| The activation of arylsulfatases 1 1 -0.7617568855468095 0.4462051169931751 |
| Metalloprotease dubs 4 8 0.7576907501632361 0.4486361377350127 |
| Translesion synthesis by polk 1 10 0.7561806564564989 0.4495408887304082 |
| Signaling by braf and raf1 fusions 6 24 0.7561479274069426 0.4495605093194914 |
| Activation of anterior hox genes in hindbrain development during early embryogenesis 8 20 -0.7560312279743412 0.449630472884007 |
| Miro gtpase cycle 1 4 0.7544741289125589 0.4505645743731832 |
| Smooth muscle contraction 5 13 -0.7543497484731917 0.4506392373906354 |
| Rhog gtpase cycle 11 40 -0.7542213592084849 0.4507163141714336 |
| Constitutive signaling by aberrant pi3k in cancer 2 5 -0.7518522340861087 0.4521399258495848 |
| G beta gamma signalling through cdc42 0 3 0.7495390464925354 0.4535323734494345 |
| Inactivation of csf3 g csf signaling 4 8 -0.7487999078531615 0.4539778152910099 |
| Ngf stimulated transcription 2 3 0.746491307509897 0.4553706806030098 |
| G alpha i signalling events 6 25 -0.7443171199334984 0.4566846464204281 |
| Phospholipase c mediated cascade fgfr4 1 1 -0.7435759162871282 0.457133077876334 |
| Phospholipase c mediated cascade fgfr2 1 1 -0.7435759162871282 0.457133077876334 |
| Passive transport by aquaporins 0 1 0.7421538135023167 0.4579941483873995 |
| Asymmetric localization of pcp proteins 3 38 0.7416355176612238 0.4583081980064714 |
| Adenylate cyclase inhibitory pathway 0 3 0.7404917277892981 0.4590016787366242 |
| Cellular response to chemical stress 10 78 0.7401428068098764 0.4592133467967558 |
| Respiratory electron transport 8 53 0.7384780933646624 0.4602239745016869 |
| Acyl chain remodelling of pg 0 1 0.73809503471218 0.4604567008369151 |
| Regulation of signaling by cbl 4 6 -0.7379064565808082 0.4605712951876364 |
| Smac xiap regulated apoptotic response 0 3 0.7362448914313438 0.4615816770485272 |
| Erk mapk targets 4 10 -0.732711174869896 0.4637346067889281 |
| Mapk targets nuclear events mediated by map kinases 4 10 -0.732711174869896 0.4637346067889281 |
| Initiation of nuclear envelope ne reformation 9 18 0.7299651741626165 0.4654114723333502 |
| Activation of rac1 4 6 -0.7296671502624674 0.4655936653243637 |
| Degradation of axin 3 37 0.7293073181187801 0.4658136967736828 |
| Synthesis of leukotrienes lt and eoxins ex 1 3 -0.7289171058115432 0.4660523704634121 |
| Homology directed repair 11 50 0.7288350875948435 0.4661025456113199 |
| Arachidonic acid metabolism 0 8 0.7287708179150025 0.4661418650788491 |
| Ptk6 expression 1 2 -0.7267998843769025 0.467348553927996 |
| Fgfr1 mutant receptor activation 3 11 -0.7229085124681249 0.4697360933729029 |
| Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 1 3 -0.7225656507861253 0.4699467777787269 |
| Triglyceride catabolism 2 7 -0.7207963953704164 0.4710347935285948 |
| Wnt ligand biogenesis and trafficking 1 4 -0.7197579257734662 0.4716740542581776 |
| Regulation of ras by gaps 3 39 0.7186211657035122 0.472374368584056 |
| Serine biosynthesis 2 3 -0.7179648718281489 0.4727789467171894 |
| Irs mediated signalling 0 4 0.7147761688752884 0.4747473630277188 |
| Signaling by scf kit 3 9 -0.7143832428355147 0.4749902309987017 |
| Signal amplification 1 7 0.7139368277157776 0.4752662433583825 |
| Foxo mediated transcription 4 12 -0.7106063564680652 0.4773282030124961 |
| Biotin transport and metabolism 2 8 0.7102923182551879 0.4775228824295163 |
| Signaling by tgf beta receptor complex 8 21 0.7102320262328106 0.4775602637925913 |
| Inlb mediated entry of listeria monocytogenes into host cell 5 6 -0.7087701650215864 0.478467115016626 |
| Erbb2 regulates cell motility 0 3 0.7078890720438269 0.4790141465037028 |
| Degradation of beta catenin by the destruction complex 5 50 0.7071204730159812 0.4794916142195184 |
| Basigin interactions 1 7 0.7068162673603731 0.4796806640206874 |
| Transcriptional regulation by runx2 4 53 0.7055451012501782 0.4804710749621899 |
| Degradation of dvl 3 38 0.7052250147746016 0.4806702164967049 |
| Shc1 events in egfr signaling 2 2 -0.7049621183773671 0.4808338108985115 |
| Pi3k events in erbb2 signaling 2 2 -0.7049621183773671 0.4808338108985115 |
| Grb2 events in erbb2 signaling 2 2 -0.7049621183773671 0.4808338108985115 |
| P75ntr negatively regulates cell cycle via sc1 1 2 0.7028048048483981 0.4821774024580674 |
| Phenylalanine metabolism 2 3 -0.7027107654151798 0.4822360173381992 |
| Activation of bad and translocation to mitochondria 4 8 -0.6942778359366958 0.4875079878503512 |
| Synthesis of pips at the late endosome membrane 3 4 0.6927215870141433 0.4884842892383703 |
| Cytosolic sensors of pathogen associated dna 5 22 -0.6885263082659853 0.4911214090223663 |
| Nuclear receptor transcription pathway 1 6 -0.686005195189844 0.4927098323425891 |
| Purinergic signaling in leishmaniasis infection 0 5 0.685978188986469 0.4927268624523666 |
| Inflammasomes 0 5 0.685978188986469 0.4927268624523666 |
| The nlrp3 inflammasome 0 5 0.685978188986469 0.4927268624523666 |
| Neddylation 5 76 0.6823416607351095 0.4950229357506313 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 2 5 0.678746057231584 0.4972987780748212 |
| Incretin synthesis secretion and inactivation 2 5 0.678746057231584 0.4972987780748212 |
| Gdp fucose biosynthesis 1 3 -0.6743998617944534 0.5000571305881722 |
| Degradation of cysteine and homocysteine 0 3 0.6723303326211205 0.5013734235212484 |
| Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 5 23 -0.6712914169645199 0.5020349013770509 |
| Listeria monocytogenes entry into host cells 5 8 -0.6708947756410857 0.5022875647539482 |
| Rho gtpases activate cit 1 10 0.6699043235525589 0.5029187834195912 |
| Inactivation of cdc42 and rac1 1 3 -0.6690242333824454 0.5034800195842077 |
| Polo like kinase mediated events 5 7 0.668570161236858 0.5037697120488231 |
| Interleukin 15 signaling 3 3 -0.6676702175652306 0.5043441249680753 |
| Interleukin 9 signaling 3 3 -0.6676702175652306 0.5043441249680753 |
| Interleukin 21 signaling 3 3 -0.6676702175652306 0.5043441249680753 |
| Extra nuclear estrogen signaling 5 13 0.6673459517301842 0.5045511808631464 |
| Trafficking of glur2 containing ampa receptors 2 7 -0.6658360217774731 0.5055159177061126 |
| Signaling by hippo 0 6 0.663717415320878 0.5068711908835462 |
| Abc transporters in lipid homeostasis 1 3 0.6623880328211202 0.5077225712358064 |
| Generation of second messenger molecules 3 6 -0.6608506522834793 0.5087080955639012 |
| Coenzyme a biosynthesis 1 3 -0.6557320279638769 0.5119965576349648 |
| Stimuli sensing channels 2 9 0.6549785566126611 0.5124815602829522 |
| Propionyl coa catabolism 1 3 -0.654603947736713 0.512722781719686 |
| Sumoylation of dna methylation proteins 1 3 0.6532269167922735 0.5136099998548196 |
| Loss of function of mecp2 in rett syndrome 2 7 -0.6523542236648131 0.5141726875979533 |
| Nef mediated cd4 down regulation 4 6 0.6522200505390472 0.5142592270446962 |
| Nef mediated cd8 down regulation 4 6 0.6522200505390472 0.5142592270446962 |
| Role of abl in robo slit signaling 2 3 -0.6520447946003303 0.5143722756329443 |
| Mrna decay by 3 to 5 exoribonuclease 7 16 -0.6508983713463884 0.5151120928596482 |
| Pexophagy 1 1 -0.6504218594762201 0.5154197610760716 |
| Myoclonic epilepsy of lafora 0 1 0.6492992948991768 0.5161449414240509 |
| Nuclear envelope breakdown 18 42 0.6448221820924301 0.5190424253193795 |
| Interleukin 23 signaling 0 3 0.6443842919169908 0.5193262679917217 |
| Regulation of tp53 activity through association with co factors 0 2 0.6437821037175327 0.5197167403087972 |
| Purine salvage 6 7 -0.6436280701386335 0.51981664345221 |
| Fc epsilon receptor fceri signaling 4 58 0.6435066239641827 0.5198954180307842 |
| Mitochondrial fatty acid beta oxidation 1 17 0.6406492899133814 0.5217505678095415 |
| Cholesterol biosynthesis 5 18 0.6379416002396928 0.5235116964667688 |
| Ion channel transport 5 29 -0.637588944845526 0.5237412939568031 |
| Dna damage bypass 4 25 0.6374051795968642 0.523860955407923 |
| Activation of caspases through apoptosome mediated cleavage 0 2 0.6347570246188933 0.5255868957916641 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 4 26 0.6300499420020674 0.5286619093937741 |
| Sars cov 1 infection 2 12 -0.6293141799373645 0.5291433898637403 |
| Synthesis of pips at the golgi membrane 1 9 0.627634627398731 0.5302433192133313 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 2 5 -0.6275254291917048 0.5303148726792326 |
| Cd28 dependent vav1 pathway 1 5 -0.6240849981343782 0.5325717655592559 |
| Sensing of dna double strand breaks 1 5 0.6200177969242427 0.5352460700785857 |
| Fcgamma receptor fcgr dependent phagocytosis 3 39 0.6178714111997464 0.5366601055976004 |
| Regulation of glucokinase by glucokinase regulatory protein 8 26 0.6167751840251091 0.5373830225220657 |
| Interleukin 20 family signaling 3 5 -0.6163110947519861 0.5376892177361656 |
| Pou5f1 oct4 sox2 nanog activate genes related to proliferation 1 1 -0.6144424027237504 0.5389230228980415 |
| Transcriptional regulation of pluripotent stem cells 1 1 -0.6144424027237504 0.5389230228980415 |
| Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members 1 1 -0.6144424027237504 0.5389230228980415 |
| Ketone body metabolism 0 4 0.6121718950149156 0.5404240343027391 |
| Cobalamin cbl vitamin b12 transport and metabolism 1 4 0.6106214438230917 0.5414502229750844 |
| Hdacs deacetylate histones 7 15 -0.6058536773026313 0.5446119219901535 |
| Degradation of gli1 by the proteasome 3 42 0.6027538600007298 0.546672445426162 |
| Molybdenum cofactor biosynthesis 0 5 0.5982241685590198 0.5496903670647759 |
| Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 3 9 -0.5977779342563113 0.5499881158623208 |
| Stabilization of p53 3 40 0.5933110993911582 0.5529729719953864 |
| Flt3 signaling 2 5 0.5914640669472195 0.5542095245348646 |
| Suppression of phagosomal maturation 5 7 -0.5912687454234536 0.5543403675927638 |
| Mitotic prophase 24 62 0.5911670508811765 0.5544084972751038 |
| Negative epigenetic regulation of rrna expression 6 27 -0.5904401355203799 0.5548956093541324 |
| Akt phosphorylates targets in the cytosol 1 3 0.5896250167788497 0.5554420759634511 |
| Cellular senescence 10 48 -0.5895700951692269 0.5554789056012954 |
| Cross presentation of soluble exogenous antigens endosomes 3 38 0.586703903928858 0.5574025853984497 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 9 62 0.585700812618294 0.5580765879109728 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 1 2 0.5850707842098739 0.5585001225407125 |
| Camk iv mediated phosphorylation of creb 1 2 0.5850707842098739 0.5585001225407125 |
| Fgfr2 mutant receptor activation 2 11 -0.58192148242791 0.5606195696936309 |
| Signaling by fgfr2 iiia tm 2 11 -0.58192148242791 0.5606195696936309 |
| Tp53 regulates transcription of genes involved in g1 cell cycle arrest 3 3 -0.581712726323112 0.5607601979153258 |
| Pyroptosis 0 8 0.5790879248872359 0.5625298472973597 |
| Signaling by fgfr1 in disease 3 12 -0.5779031362780874 0.563329517757309 |
| Plasma lipoprotein remodeling 1 2 0.5775468866370065 0.5635700748068131 |
| Platelet calcium homeostasis 2 5 -0.5760833041588017 0.5645588759294164 |
| Traf6 mediated induction of tak1 complex within tlr4 complex 0 2 0.5756227150560056 0.5648702240439438 |
| Dna double strand break repair 16 63 0.5721468759354733 0.5672224741309695 |
| Apoptotic factor mediated response 3 8 -0.570498149582835 0.568339876799965 |
| Mitotic g1 phase and g1 s transition 8 83 0.5687485663862737 0.5695267837983147 |
| Ub specific processing proteases 7 76 0.5684677853666339 0.569717374097225 |
| Transcriptional regulation of granulopoiesis 0 9 0.5667813003860506 0.5708627767373993 |
| Cell death signalling via nrage nrif and nade 5 13 -0.5666053955701374 0.5709823083648515 |
| Eph ephrin signaling 10 35 -0.5662358313234711 0.5712334751215116 |
| Sumoylation of transcription cofactors 2 12 0.5621242012845343 0.5740314004118683 |
| Esr mediated signaling 17 49 0.5620315368817456 0.5740945323805235 |
| Trans golgi network vesicle budding 9 35 -0.5598652680737013 0.5755713406768832 |
| Rnd1 gtpase cycle 3 15 0.5591015698855052 0.5760924034144472 |
| Hedgehog on state 3 45 0.5571657753553616 0.5774141708320082 |
| Peroxisomal protein import 1 22 -0.5559736366646607 0.5782288772946071 |
| Cellular response to hypoxia 3 42 0.5541430415945983 0.5794809555308273 |
| Tcf dependent signaling in response to wnt 6 64 0.5536707924430968 0.5798041676793588 |
| Polymerase switching 0 14 0.5535871192234963 0.5798614433023859 |
| Diseases of mismatch repair mmr 1 3 0.5535713912579373 0.5798722096361899 |
| Glutamate and glutamine metabolism 6 8 -0.553209486053968 0.5801199720962484 |
| G1 s dna damage checkpoints 3 42 0.550863760362464 0.5817270717363439 |
| Transferrin endocytosis and recycling 4 11 -0.5492325806776672 0.58284584810619 |
| Signaling by nuclear receptors 16 67 0.5486427026281195 0.5832506744481498 |
| Sensory perception 5 31 -0.5476032056208227 0.583964387831416 |
| Runx3 regulates wnt signaling 0 1 0.5461481206981437 0.5849641242212316 |
| Lrr flii interacting protein 1 lrrfip1 activates type i ifn production 0 1 0.5461481206981437 0.5849641242212316 |
| Binding of tcf lef ctnnb1 to target gene promoters 0 1 0.5461481206981437 0.5849641242212316 |
| Nr1h2 nr1h3 regulate gene expression linked to gluconeogenesis 1 1 -0.5444550025101308 0.5861284050446127 |
| Nr1h2 nr1h3 regulate gene expression linked to triglyceride lipolysis in adipose 1 1 -0.5444550025101308 0.5861284050446127 |
| Nr1h2 nr1h3 regulate gene expression to limit cholesterol uptake 1 1 -0.5444550025101308 0.5861284050446127 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 3 4 -0.5437872950338741 0.5865878526407271 |
| Cristae formation 7 19 -0.5424220302133571 0.5875278066538183 |
| Condensation of prophase chromosomes 5 12 0.5412525559940213 0.5883335170134323 |
| Interleukin 27 signaling 3 5 -0.5366203937809275 0.59152985415444 |
| Interleukin 35 signalling 3 5 -0.5366203937809275 0.59152985415444 |
| Rnd3 gtpase cycle 6 17 0.5365746409141416 0.5915614648222083 |
| Loss of mecp2 binding ability to the ncor smrt complex 2 3 -0.5349641119089295 0.5926746738469313 |
| Interleukin 12 signaling 6 30 0.53495684768978 0.5926796971017807 |
| Oas antiviral response 2 4 -0.5324922461046673 0.5943851107428619 |
| Signaling by notch2 2 2 -0.5278039305087104 0.5976354288189303 |
| Notch2 activation and transmission of signal to the nucleus 2 2 -0.5278039305087104 0.5976354288189303 |
| Tp53 regulates metabolic genes 6 37 0.5270673752132654 0.5981468015599851 |
| Constitutive signaling by overexpressed erbb2 2 4 -0.5268721689029144 0.5982823619300932 |
| Er quality control compartment erqc 1 2 0.5251244554217639 0.5994966765205216 |
| Sumoylation of immune response proteins 0 2 0.5238759401949682 0.6003648301376328 |
| Regulation of runx2 expression and activity 3 44 0.5238658619182421 0.6003718403680842 |
| Interleukin 10 signaling 2 3 -0.5232954198624842 0.6007686877944776 |
| Nicotinate metabolism 0 3 0.5230135900066161 0.6009647960572462 |
| Transport of the slbp dependant mature mrna 12 30 0.5221932211744188 0.6015358053600779 |
| Regulation of lipid metabolism by pparalpha 9 26 0.5204253881306582 0.602767118735325 |
| Rho gtpases activate iqgaps 3 12 0.5177590821337941 0.6046263703505612 |
| Golgi to er retrograde transport 19 74 0.515563050534784 0.606159622525769 |
| Creb phosphorylation 1 2 -0.5148314902880512 0.6066707781513421 |
| Nuclear envelope ne reassembly 19 50 0.5143709826504077 0.6069926427209122 |
| Rac2 gtpase cycle 10 40 -0.5133360406632206 0.6077162773086391 |
| Adp signalling through p2y purinoceptor 1 0 2 0.5125981255709416 0.6082324646598503 |
| Signal attenuation 2 3 -0.5116662024320419 0.608884643804716 |
| Iron uptake and transport 2 18 0.5106454843034194 0.6095993204338208 |
| Caspase mediated cleavage of cytoskeletal proteins 0 8 0.5087397009314909 0.6109346904361612 |
| Binding and uptake of ligands by scavenger receptors 2 8 -0.5081788709921042 0.6113279071663291 |
| Runx3 regulates cdkn1a transcription 1 1 -0.5043474417397649 0.6140172447375434 |
| Activation of puma and translocation to mitochondria 1 1 -0.5043474417397649 0.6140172447375434 |
| Activation of noxa and translocation to mitochondria 1 1 -0.5043474417397649 0.6140172447375434 |
| Termination of translesion dna synthesis 2 18 0.5039580947890727 0.6142908248476073 |
| Cd28 dependent pi3k akt signaling 1 2 0.5036091364716947 0.6145360709383676 |
| Rnd2 gtpase cycle 7 17 0.499749259668076 0.617251642471669 |
| Cd209 dc sign signaling 4 6 -0.4994601914738329 0.617455224463165 |
| Irf3 mediated induction of type i ifn 1 5 -0.4980187089086978 0.6184708555764997 |
| Cyclin a cdk2 associated events at s phase entry 3 45 0.4960724931006297 0.6198432654683619 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 0 5 0.4952411391018522 0.6204299143487675 |
| Netrin mediated repulsion signals 0 1 0.4948938259724114 0.6206750690637062 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 1 4 0.4941808779255877 0.6211784431415757 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0 2 0.4921441615649732 0.6226174349926406 |
| Urea cycle 0 2 0.4878012817031239 0.6256906034705794 |
| Rac1 gtpase cycle 6 54 0.4865567723882936 0.6265724636374888 |
| Hdl clearance 0 2 0.4831188141555703 0.6290113759977143 |
| Translesion synthesis by polh 1 13 0.4825646938926746 0.6294048528740515 |
| Rac3 gtpase cycle 5 40 0.4812673806040946 0.6303264772727013 |
| Aspartate and asparagine metabolism 2 5 -0.4812226244971183 0.6303582827391274 |
| Interleukin receptor shc signaling 2 2 -0.4764525031858688 0.6337520376342205 |
| Activation of gene expression by srebf srebp 6 20 -0.4759100804622495 0.6341384402828172 |
| Degradation of the extracellular matrix 2 9 0.4742065383865509 0.6353526312840589 |
| Deposition of new cenpa containing nucleosomes at the centromere 2 9 -0.4699846857706537 0.6383659588656048 |
| Signaling by kit in disease 3 5 -0.4690480974111825 0.6390352570423983 |
| Nostrin mediated enos trafficking 0 2 0.4674030580635853 0.6402115351022015 |
| Enos activation 0 4 0.4659078427478205 0.6412814671504918 |
| Diseases associated with o glycosylation of proteins 0 2 0.4654645286335574 0.6415988330640068 |
| Hdr through single strand annealing ssa 7 19 0.4649717770131631 0.6419516678464867 |
| The phototransduction cascade 2 7 -0.4646458684470171 0.6421850790903991 |
| Negative regulation of flt3 1 2 0.4617304570352751 0.6442746268886235 |
| Rhoq gtpase cycle 6 26 -0.4602941534843124 0.6453050971284908 |
| Regulation of kit signaling 3 5 -0.4567700372538839 0.6478363441811656 |
| Glycogen metabolism 1 10 -0.4532211518147175 0.6503895029592948 |
| Senescence associated secretory phenotype sasp 5 25 -0.4521839775520758 0.6511364498193359 |
| Oncogenic mapk signaling 3 28 0.4511034462651619 0.6519149939830176 |
| Separation of sister chromatids 21 110 0.4498817762056019 0.6527956885742183 |
| Nade modulates death signalling 0 2 0.4494056713161072 0.6531390408923992 |
| Cilium assembly 15 65 0.4491639267884943 0.6533134077972327 |
| Copii mediated vesicle transport 11 32 -0.4490938597843703 0.6533639496748203 |
| Synthesis of diphthamide eef2 1 5 0.4486517634813278 0.6536828864795527 |
| Mitochondrial translation 13 55 -0.4485864130523128 0.6537300369086143 |
| Pp2a mediated dephosphorylation of key metabolic factors 1 3 0.4469756647816846 0.654892630619694 |
| Rap1 signalling 3 4 -0.4467232719262063 0.6550748767696266 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 2 18 0.4458008563372507 0.6557411031833169 |
| Snrnp assembly 17 40 0.4445019264162966 0.656679736385716 |
| Ticam1 rip1 mediated ikk complex recruitment 1 4 -0.4433867089626452 0.6574860477836755 |
| Vxpx cargo targeting to cilium 4 10 -0.4406929780913112 0.6594352807920729 |
| Notch4 activation and transmission of signal to the nucleus 1 2 -0.4403043902279088 0.6597166614484835 |
| Pi metabolism 5 21 0.4399684707405742 0.6599599431688921 |
| Tlr3 mediated ticam1 dependent programmed cell death 0 2 0.438868071073154 0.6607571332332247 |
| Trif mediated programmed cell death 0 2 0.438868071073154 0.6607571332332247 |
| Rrna modification in the mitochondrion 1 2 0.4384215964851015 0.6610806938520137 |
| Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 1 3 0.4380590792364518 0.6613434570928334 |
| Synthesis of substrates in n glycan biosythesis 4 18 -0.4379976305211294 0.661388001079132 |
| Negative regulators of ddx58 ifih1 signaling 0 7 0.436604478485572 0.6623982141877189 |
| Collagen biosynthesis and modifying enzymes 2 10 0.4360717232210459 0.6627846923330565 |
| Signaling by fgfr2 in disease 3 13 -0.4360713012926597 0.662784998449347 |
| Assembly and cell surface presentation of nmda receptors 3 11 0.4355849946342993 0.6631378597138544 |
| Glycerophospholipid catabolism 1 2 0.4354545451014637 0.6632325258496996 |
| Rna polymerase i promoter escape 3 17 -0.4338677923717677 0.6643844491909123 |
| Tnfr1 induced nfkappab signaling pathway 0 6 0.4323374568302928 0.665496167279104 |
| Regulation of hsf1 mediated heat shock response 14 53 0.4308139189404948 0.6666036780749514 |
| Class i peroxisomal membrane protein import 2 9 0.430564008077163 0.6667854161425086 |
| Export of viral ribonucleoproteins from nucleus 15 28 0.4291629850841503 0.667804618120857 |
| Gap filling dna repair synthesis and ligation in gg ner 3 19 0.428623987601299 0.6681968859040761 |
| Regulation of tp53 activity through phosphorylation 11 35 0.4273545891833955 0.6691210776409566 |
| Nucleotide salvage 8 10 -0.42707128267554 0.6693274088268806 |
| Traf6 mediated irf7 activation in tlr7 8 or 9 signaling 1 1 -0.4252463835411003 0.6706570745504532 |
| Sumoylation of dna damage response and repair proteins 15 44 0.4238084253188127 0.6717055330862824 |
| B wich complex positively regulates rrna expression 3 21 -0.4215823644904844 0.6733298808484969 |
| G alpha s signalling events 1 6 0.4210738438949369 0.6737011605422241 |
| Other semaphorin interactions 1 2 -0.4204755004908236 0.6741381232332391 |
| Formation of apoptosome 2 3 -0.4201734517825677 0.6743587473891082 |
| Glucagon like peptide 1 glp1 regulates insulin secretion 2 7 -0.4200296176608106 0.674463817379185 |
| Triglyceride metabolism 2 8 -0.4186142468141971 0.6754980758496703 |
| Integrin cell surface interactions 2 4 -0.4168968893984728 0.6767538288736337 |
| Rna polymerase iii transcription initiation from type 1 promoter 2 12 -0.4155309207058166 0.6777532844394845 |
| Negative regulation of notch4 signaling 2 40 0.4129352329743357 0.6796540664711237 |
| Infection with mycobacterium tuberculosis 9 13 -0.4128943486408314 0.6796840217714328 |
| Response of mtb to phagocytosis 9 13 -0.4128943486408314 0.6796840217714328 |
| Signaling by notch 4 65 0.4100573878419642 0.6817638504237635 |
| Homologous dna pairing and strand exchange 7 21 0.4088916363540904 0.6826191870652758 |
| Maturation of protein 3a 0 1 0.4087408916898334 0.6827298214261739 |
| Signaling by notch1 pest domain mutants in cancer 2 9 -0.4085985639369058 0.6828342847133335 |
| Pi5p regulates tp53 acetylation 1 2 -0.4085062806732238 0.6829020204498193 |
| Uptake and actions of bacterial toxins 2 7 -0.4080710450191956 0.6832215169892244 |
| Sting mediated induction of host immune responses 1 6 -0.4076323878280144 0.6835435826214975 |
| G alpha 12 13 signalling events 1 12 -0.4068236257507155 0.6841375331786959 |
| Activation of rac1 downstream of nmdars 1 2 -0.4056958448139935 0.6849660957229873 |
| Biosynthesis of specialized proresolving mediators spms 2 2 -0.4056578404023744 0.6849940235631116 |
| Apoptotic execution phase 6 34 -0.4051132396388248 0.6853942749837609 |
| Rhobtb3 atpase cycle 2 4 -0.405047838800751 0.6854423469218207 |
| Interleukin 12 family signaling 6 33 0.4008043883257922 0.6885641477441 |
| Regulated proteolysis of p75ntr 1 2 -0.4006982043543846 0.6886423329944455 |
| Synthesis of dna 10 89 0.4004696057054054 0.6888106657577697 |
| Mitochondrial calcium ion transport 5 16 0.4000543255730125 0.689116504241323 |
| Regulation of insulin secretion 4 14 -0.3988957124358013 0.6899700485478071 |
| Irak4 deficiency tlr2 4 1 1 -0.3978020499552575 0.6907761060692648 |
| Regulation of tlr by endogenous ligand 1 1 -0.3978020499552575 0.6907761060692648 |
| Signaling by fgfr in disease 5 23 -0.3977009820718111 0.6908506134296153 |
| Polymerase switching on the c strand of the telomere 0 16 0.3976915103846609 0.6908575961218117 |
| Dna damage recognition in gg ner 8 19 -0.3956523517953354 0.6923615107450649 |
| Thromboxane signalling through tp receptor 0 3 0.3953728588856307 0.6925677362921521 |
| Heme signaling 1 8 0.3939153642694331 0.6936435265666894 |
| Metabolism of ingested semet sec mesec into h2se 1 1 -0.3933008003157355 0.6940973272013036 |
| Sealing of the nuclear envelope ne by escrt iii 3 11 -0.3927349198984981 0.6945152764020428 |
| P38mapk events 1 3 -0.3921228657300556 0.6949674332847806 |
| Striated muscle contraction 3 6 -0.3915562771485326 0.69538609906696 |
| Flt3 signaling in disease 2 7 0.3904284732595239 0.6962197365568024 |
| Gab1 signalosome 2 5 -0.3893724112450805 0.6970006775693323 |
| Integrin signaling 2 5 -0.3887830118590372 0.6974366687131934 |
| Platelet aggregation plug formation 2 5 -0.3887830118590372 0.6974366687131934 |
| Nuclear events kinase and transcription factor activation 2 13 -0.388656732104659 0.6975300935095845 |
| Met activates ras signaling 2 3 -0.3868293958286516 0.6988825134103498 |
| Crmps in sema3a signaling 2 6 -0.3860392862137589 0.6994675735028228 |
| Collagen formation 2 11 0.3842868094572265 0.7007658833856301 |
| Release of apoptotic factors from the mitochondria 2 2 -0.384025711960523 0.7009593905460949 |
| Platelet homeostasis 6 12 0.3832918551278187 0.7015033776583683 |
| Hats acetylate histones 8 23 -0.3827934552662739 0.7018729145178166 |
| Runx1 regulates transcription of genes involved in differentiation of myeloid cells 1 2 -0.3824147139120961 0.7021537781421279 |
| Antigen presentation folding assembly and peptide loading of class i mhc 8 14 0.3795719696817801 0.7042631712092062 |
| Unblocking of nmda receptors glutamate binding and activation 1 5 0.3777412117776779 0.7056228495494345 |
| Ras activation upon ca2 influx through nmda receptor 1 5 0.3777412117776779 0.7056228495494345 |
| Negative regulation of nmda receptor mediated neuronal transmission 1 5 0.3777412117776779 0.7056228495494345 |
| Long term potentiation 1 5 0.3777412117776779 0.7056228495494345 |
| Formation of fibrin clot clotting cascade 1 3 -0.3765666801710255 0.7064956533273727 |
| Signaling by egfr 9 16 -0.3730749372407016 0.7090926714473196 |
| Rora activates gene expression 1 4 0.3729745483532654 0.7091673868627852 |
| Interleukin 4 and interleukin 13 signaling 0 14 0.3682738434428184 0.7126690540148739 |
| Attachment of gpi anchor to upar 1 3 -0.3676477688604987 0.7131358912018668 |
| Cd28 co stimulation 2 9 0.3660441224523297 0.7143321519182488 |
| Growth hormone receptor signaling 2 6 -0.3633312140068169 0.7163574788196518 |
| Transcriptional activation of mitochondrial biogenesis 3 14 0.3630673734667674 0.7165545562476501 |
| Regulation of beta cell development 0 3 0.3602648493562274 0.7186490830418832 |
| Pcna dependent long patch base excision repair 3 19 0.3576035916654596 0.7206399900743059 |
| Deubiquitination 11 100 0.357019220845101 0.7210774165613707 |
| Dscam interactions 3 3 -0.3532200195854083 0.7239235005184932 |
| Toll like receptor tlr1 tlr2 cascade 4 23 -0.3527668549979855 0.7242632341397401 |
| Cell cell communication 7 29 -0.3522944642271189 0.7246174392857088 |
| Endogenous sterols 0 2 0.3519007902382929 0.7249126665358965 |
| Toll like receptor 9 tlr9 cascade 4 24 -0.3484626151882535 0.7274927852850026 |
| Intra golgi traffic 7 15 -0.3469373705667555 0.7286383706295836 |
| Leishmania infection 4 48 0.3439074554224385 0.7309158848698825 |
| Complex i biogenesis 4 28 0.3434520568595325 0.7312584027120601 |
| Depolymerisation of the nuclear lamina 6 10 -0.343157002316723 0.7314803499916327 |
| Notch3 intracellular domain regulates transcription 2 3 -0.342348601047774 0.7320885643828996 |
| Regulation of localization of foxo transcription factors 2 6 -0.3415326912660144 0.7327025986323137 |
| Recycling pathway of l1 6 21 -0.3403002121761573 0.7336304573877719 |
| Rhoa gtpase cycle 13 54 -0.340252044036369 0.7336667281702893 |
| Parasite infection 2 30 0.3397138232564602 0.7340720507676186 |
| Pre notch expression and processing 1 11 0.3385501382031676 0.7349486503978397 |
| Sumoylation of chromatin organization proteins 11 35 0.3383101086701924 0.7351295067606962 |
| G protein mediated events 3 13 -0.3382534735014318 0.7351721821124211 |
| Scf skp2 mediated degradation of p27 p21 2 42 0.3380938178312145 0.7352924891803985 |
| Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0 2 0.3374087624259918 0.7358087800882716 |
| Ddx58 ifih1 mediated induction of interferon alpha beta 3 18 -0.3360816446240438 0.736809299663991 |
| Carboxyterminal post translational modifications of tubulin 1 6 0.3355584029093116 0.7372038965176295 |
| Negative feedback regulation of mapk pathway 1 3 -0.3351312193457351 0.7375261035773732 |
| Post translational modification synthesis of gpi anchored proteins 1 6 -0.3351180397898574 0.7375360451102377 |
| Fanconi anemia pathway 1 7 0.3347196479646426 0.7378365786412906 |
| Rhob gtpase cycle 6 30 -0.3303896581777436 0.74110555480872 |
| Ercc6 csb and ehmt2 g9a positively regulate rrna expression 3 14 -0.3303389416690645 0.7411438716620642 |
| Dcc mediated attractive signaling 4 4 -0.3289328076224291 0.7422064759781488 |
| Deadenylation of mrna 4 17 0.328822991522916 0.7422894838508087 |
| Ras signaling downstream of nf1 loss of function variants 0 1 0.3288037714194942 0.742304012264718 |
| Cell surface interactions at the vascular wall 1 18 0.3274117526787683 0.743356478545224 |
| Cytochrome c mediated apoptotic response 1 5 0.326098368625578 0.74434993127402 |
| Map3k8 tpl2 dependent mapk1 3 activation 2 6 0.3260267979572598 0.7444040800610345 |
| Microrna mirna biogenesis 2 12 -0.3258495645422862 0.7445381763866616 |
| Translesion synthesis by y family dna polymerases bypasses lesions on dna template 2 21 0.3226235202650215 0.746980378887254 |
| Assembly of collagen fibrils and other multimeric structures 0 1 0.3221685874327356 0.7473249804360518 |
| Type i hemidesmosome assembly 0 1 0.3221685874327356 0.7473249804360518 |
| Neurexins and neuroligins 2 9 -0.3221653304994328 0.7473274476731 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 5 13 -0.3203039710761966 0.7487379131296352 |
| Copi independent golgi to er retrograde traffic 8 29 0.3194409190110523 0.7493921859680759 |
| Transport and synthesis of paps 1 2 0.3193056752897957 0.7494947295080492 |
| S phase 14 100 0.3190172662971834 0.7497134197280708 |
| Cooperation of pdcl phlp1 and tric cct in g protein beta folding 6 11 0.3187432271470646 0.7499212324540974 |
| Signaling by notch4 2 43 0.3172973066673465 0.7510180208320831 |
| Hdms demethylate histones 1 9 0.3165185417179172 0.7516089537914425 |
| Keratinization 3 6 -0.3162839165271504 0.751787017800015 |
| Formation of the cornified envelope 3 6 -0.3162839165271504 0.751787017800015 |
| Rho gtpases activate paks 1 11 -0.3148431159400897 0.7528807734511385 |
| Trna processing in the mitochondrion 0 4 0.3146422969298282 0.7530332607362369 |
| Sema3a plexin repulsion signaling by inhibiting integrin adhesion 3 4 0.3144232323218127 0.7531996133834113 |
| Il 6 type cytokine receptor ligand interactions 1 2 -0.312961237697168 0.7543101116934112 |
| Signaling by mapk mutants 1 2 -0.3122030759685568 0.7548861945787653 |
| Raf independent mapk1 3 activation 2 8 -0.3100539841009994 0.7565199043436115 |
| Ion homeostasis 4 13 -0.3096021435354708 0.756863526032832 |
| Cardiac conduction 4 13 -0.3096021435354708 0.756863526032832 |
| Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells 0 1 0.3091262200858858 0.7572255145755686 |
| Runx3 regulates notch signaling 0 1 0.3091262200858858 0.7572255145755686 |
| Gap junction assembly 1 5 0.3085635952253419 0.7576535171157972 |
| Transport of connexons to the plasma membrane 1 5 0.3085635952253419 0.7576535171157972 |
| Sumoylation of rna binding proteins 9 31 0.3083511346743603 0.7578151604070051 |
| Neutrophil degranulation 56 176 -0.3078965172683276 0.75816107596487 |
| Synthesis of wybutosine at g37 of trna phe 2 2 -0.3078669752494707 0.7581835559796031 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 2 5 -0.3070153296302325 0.7588317039951518 |
| Grb2 sos provides linkage to mapk signaling for integrins 1 2 -0.3048873314068757 0.7604519647638168 |
| Mismatch repair 4 12 0.303907081180536 0.7611986828009158 |
| Estrogen dependent gene expression 9 35 0.3036095267028865 0.7614253927440275 |
| G2 phase 2 2 -0.3029923085704455 0.7618957231354564 |
| Fasl cd95l signaling 1 2 0.3019280052903137 0.7627069463080214 |
| Rna polymerase iii transcription 2 13 -0.297635532312748 0.7659813520921941 |
| Sumoylation of transcription factors 1 5 -0.2974700221960571 0.7661076915178802 |
| Activation of bh3 only proteins 5 11 -0.2955786171331386 0.7675519054006041 |
| Kinesins 6 20 0.2945536089364957 0.7683349052394108 |
| Intra golgi and retrograde golgi to er traffic 12 98 0.2922029002299279 0.7701314942926509 |
| Signaling by flt3 fusion proteins 1 5 0.2919292812248832 0.7703406949741949 |
| Ncam signaling for neurite out growth 3 6 -0.291880755955237 0.7703777976489641 |
| Transmission across chemical synapses 10 44 -0.2917057886096563 0.7705115829587246 |
| Copi dependent golgi to er retrograde traffic 12 50 0.2903194116400241 0.7715718897107742 |
| Cdc42 gtpase cycle 3 40 0.2896890116731769 0.7720541634597446 |
| Intrinsic pathway for apoptosis 11 22 -0.2873684699962142 0.7738302007913442 |
| Tbc rabgaps 5 15 -0.2866404293889874 0.7743876546169153 |
| Downstream signaling of activated fgfr1 2 3 -0.286201828995606 0.7747235429763819 |
| Downstream signaling of activated fgfr4 2 3 -0.286201828995606 0.7747235429763819 |
| Downstream signaling of activated fgfr3 2 3 -0.286201828995606 0.7747235429763819 |
| Signaling by ntrk3 trkc 2 3 -0.286201828995606 0.7747235429763819 |
| Downstream signaling of activated fgfr2 2 3 -0.286201828995606 0.7747235429763819 |
| Nonhomologous end joining nhej 7 21 0.2859968623621314 0.7748805247065627 |
| Tnf signaling 2 9 -0.2854410607409157 0.7753062534569337 |
| Sensory processing of sound by outer hair cells of the cochlea 6 15 0.2854154981600279 0.7753258353162797 |
| Sema4d in semaphorin signaling 2 8 0.2835170879042336 0.7767804845598738 |
| Common pathway of fibrin clot formation 0 1 0.2830941811933727 0.7771046419637453 |
| Cell junction organization 4 18 -0.2822604133695034 0.7777438374727474 |
| Signaling by wnt 10 89 0.2813677108881943 0.7784283811089523 |
| Regulation of runx3 expression and activity 2 38 0.2785959477331174 0.7805549228739068 |
| Platelet adhesion to exposed collagen 1 2 -0.2771852933377631 0.7816378315930255 |
| Activation of the ap 1 family of transcription factors 1 3 -0.2768894930792213 0.7818649606093064 |
| Dna double strand break response 8 22 0.2740837185456165 0.7840202856349858 |
| Mrna capping 2 16 -0.2731973908385549 0.7847014855303864 |
| Response to elevated platelet cytosolic ca2 6 33 -0.2712885801482865 0.7861690889712987 |
| Ca dependent events 2 8 -0.2708009090012842 0.7865441607100436 |
| Pkmts methylate histone lysines 3 20 0.269188329709035 0.7877847604719386 |
| Sema4d induced cell migration and growth cone collapse 2 7 0.2678867018601477 0.788786530091613 |
| Class b 2 secretin family receptors 1 2 0.2677485177470156 0.7888929010359051 |
| Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 1 3 -0.2672266003726165 0.789294696485977 |
| Cd163 mediating an anti inflammatory response 0 2 0.2653137911334398 0.7907677413056202 |
| Transcriptional regulation by runx3 2 42 0.2626689908753418 0.7928057194172493 |
| Hiv transcription initiation 2 15 -0.26218920889733 0.7931755725211906 |
| Metabolism of steroids 8 46 0.2619648440855889 0.7933485462648846 |
| Nephrin family interactions 5 9 0.2616648385609607 0.7935798509970928 |
| Sema3a pak dependent axon repulsion 7 8 0.2615628188398783 0.7936585125011497 |
| Runx1 regulates expression of components of tight junctions 1 3 -0.260249426394294 0.7946713806127335 |
| Hdl assembly 1 2 -0.2581955980653322 0.7962559550177819 |
| Pka mediated phosphorylation of key metabolic factors 1 2 -0.2581955980653322 0.7962559550177819 |
| Regulation of innate immune responses to cytosolic dna 2 4 -0.2548082391277299 0.7988712113771828 |
| Alk mutants bind tkis 3 7 0.2543639195867141 0.799214422437565 |
| Pi3k akt signaling in cancer 3 9 0.2536345437755572 0.7997779069998252 |
| Golgi cisternae pericentriolar stack reorganization 4 11 0.2520283931064316 0.8010191174817352 |
| Hs gag biosynthesis 1 1 -0.2520129170991222 0.8010310795701654 |
| Digestion 0 1 0.2518561389434158 0.8011522629492913 |
| Digestion and absorption 0 1 0.2518561389434158 0.8011522629492913 |
| Regulation of cholesterol biosynthesis by srebp srebf 6 26 -0.2510492709655841 0.8017760159446128 |
| Resolution of abasic sites ap sites 4 28 0.2508246590151493 0.8019496757447437 |
| Epigenetic regulation of gene expression 11 47 -0.2507949698854865 0.8019726307691288 |
| P75 ntr receptor mediated signalling 7 20 -0.2495662941440082 0.8029227672606021 |
| Dissolution of fibrin clot 2 2 -0.2490618983942357 0.8033129015672522 |
| Rho gtpases activate rocks 2 10 0.246828090961154 0.8050412695327362 |
| Suppression of apoptosis 1 4 -0.2450916832454882 0.8063854423850869 |
| Signaling by ntrks 9 33 -0.2441367075077665 0.8071249440207298 |
| P75ntr signals via nf kb 2 2 -0.2433600105276782 0.8077265196606955 |
| Nf kb is activated and signals survival 2 2 -0.2433600105276782 0.8077265196606955 |
| Irak1 recruits ikk complex 1 3 -0.2426881029172107 0.8082470244712701 |
| Metabolism of steroid hormones 2 5 -0.2385114636350806 0.8114844251830973 |
| Citric acid cycle tca cycle 9 19 -0.2380795078540391 0.8118194281857958 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0 13 0.2373935342290458 0.8123515053272661 |
| Ntrk2 activates rac1 1 1 -0.2366384602681049 0.8129372804928172 |
| Activated ntrk2 signals through fyn 1 1 -0.2366384602681049 0.8129372804928172 |
| Killing mechanisms 1 1 -0.2366384602681049 0.8129372804928172 |
| Anchoring of the basal body to the plasma membrane 8 34 0.2358063878136397 0.813582911164759 |
| Insulin receptor recycling 3 10 -0.2356802402342602 0.81368080403091 |
| Meiotic recombination 3 15 -0.2355147192734923 0.8138092557874053 |
| Notch hlh transcription pathway 3 6 -0.2341646929129526 0.8148571240248961 |
| Receptor mediated mitophagy 1 3 0.2333373170292329 0.8154994834253009 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 2 5 0.2324711438167388 0.8161720972347273 |
| Methylation 3 9 -0.2290020058833691 0.8188673570820573 |
| Ticam1 traf6 dependent induction of tak1 complex 1 1 -0.2278162585693373 0.8197890865165887 |
| Irak2 mediated activation of tak1 complex 1 1 -0.2278162585693373 0.8197890865165887 |
| Alpha protein kinase 1 signaling pathway 1 1 -0.2278162585693373 0.8197890865165887 |
| Tristetraprolin ttp zfp36 binds and destabilizes mrna 5 14 -0.2275982573506402 0.8199585748340548 |
| Lagging strand synthesis 3 20 0.2271206428647501 0.8203299327649347 |
| Assembly of the orc complex at the origin of replication 0 10 0.2256011788344557 0.8215116239098637 |
| Semaphorin interactions 3 21 -0.2245976322417722 0.8222923070317354 |
| Tp53 regulates transcription of genes involved in g2 cell cycle arrest 2 8 0.2244452509831441 0.8224108634995093 |
| Postmitotic nuclear pore complex npc reformation 6 23 0.2228033337704046 0.8236885732524433 |
| Foxo mediated transcription of oxidative stress metabolic and neuronal genes 1 5 -0.2204135481790267 0.8255490949328248 |
| Rab gefs exchange gtp for gdp on rabs 11 32 -0.2203968075321948 0.8255621315112367 |
| Estrogen biosynthesis 0 1 0.2198940753065731 0.8259536506121792 |
| Hsf1 dependent transactivation 3 14 0.2187021038100366 0.8268821100554473 |
| Clec7a dectin 1 induces nfat activation 2 3 -0.2182304621159565 0.827249551677592 |
| Myd88 independent tlr4 cascade 4 26 -0.2149666143886446 0.8297933479095574 |
| Cargo trafficking to the periciliary membrane 7 22 -0.214072034571755 0.830490883455943 |
| Resolution of ap sites via the multiple nucleotide patch replacement pathway 3 23 0.2137107714861298 0.8307726109689799 |
| Ksrp khsrp binds and destabilizes mrna 5 14 -0.2117765362710903 0.8322813746754494 |
| Activated tak1 mediates p38 mapk activation 3 4 0.2116516239128634 0.8323788315120146 |
| N glycan trimming in the er and calnexin calreticulin cycle 2 14 -0.2111062816571012 0.8328043386376873 |
| G2 m checkpoints 13 93 0.2106457576795196 0.833163703863699 |
| Downregulation of erbb2 erbb3 signaling 0 2 0.2083576030862365 0.8349497576543845 |
| Rhoc gtpase cycle 9 38 -0.2075876842842072 0.83555092141091 |
| Vitamin b5 pantothenate metabolism 1 5 -0.2075280883313153 0.835597458805605 |
| Bicarbonate transporters 0 1 0.2074722619264627 0.835641053150975 |
| Regulation of tnfr1 signaling 2 7 -0.2063165942173161 0.8365436170599612 |
| Phase ii conjugation of compounds 13 30 -0.2042679343448403 0.8381441263447666 |
| Insulin receptor signalling cascade 1 6 0.2026548389661808 0.839404823926563 |
| Wnt mediated activation of dvl 1 2 0.2008928588319428 0.8407823517124886 |
| Golgi associated vesicle biogenesis 7 29 -0.2008377166776418 0.8408254701068683 |
| Erythrocytes take up carbon dioxide and release oxygen 0 1 0.2003943273872764 0.8411721956027738 |
| Interleukin 6 signaling 2 6 -0.1992796118197784 0.8420440267314464 |
| Interleukin 6 family signaling 2 6 -0.1992796118197784 0.8420440267314464 |
| Processing of dna double strand break ends 11 34 0.19925428680829 0.8420638359515786 |
| Trafficking of myristoylated proteins to the cilium 0 3 0.1991442095719613 0.842149939510427 |
| Class i mhc mediated antigen processing presentation 12 119 0.1985887490276681 0.842584455296616 |
| Trna processing 16 64 0.1984623037337005 0.8426833753725496 |
| Telomere maintenance 15 45 -0.1982906223855309 0.8428176882745315 |
| Rhoh gtpase cycle 5 26 -0.1964135382180462 0.8442865006737124 |
| Ros and rns production in phagocytes 1 9 0.1932705607837873 0.8467470807299449 |
| Dual incision in gg ner 2 24 0.1932642084517805 0.8467520553773613 |
| Role of second messengers in netrin 1 signaling 2 2 -0.1919499395074089 0.8477814186310573 |
| Egfr interacts with phospholipase c gamma 2 2 -0.1919499395074089 0.8477814186310573 |
| Signaling by fgfr4 in disease 2 2 -0.1919499395074089 0.8477814186310573 |
| Mitotic prometaphase 29 98 0.1918863136421219 0.8478312583601095 |
| Uptake and function of anthrax toxins 0 2 0.1917501354532539 0.8479379321805385 |
| Signaling by erbb2 8 15 -0.1913302121476215 0.8482668924263792 |
| Oxidative stress induced senescence 4 18 0.1911857887118123 0.8483800372186812 |
| Mitochondrial trna aminoacylation 5 17 0.1910578786916294 0.8484802476129452 |
| Mitotic g2 g2 m phases 11 96 0.1886984367905293 0.8503291768391081 |
| Nicotinamide salvaging 0 2 0.1877175720764691 0.8510980546213578 |
| Gap junction trafficking and regulation 3 11 0.1875556061007951 0.8512250297446888 |
| Regulation of tp53 expression and degradation 5 12 0.1869420379193652 0.851706078662275 |
| Synthesis of pips at the er membrane 0 3 0.1854599947848055 0.8528682554431415 |
| Irf3 mediated activation of type 1 ifn 1 1 -0.1854304131068813 0.8528914558279734 |
| Ns1 mediated effects on host pathways 9 32 0.1848057437281762 0.853381402619199 |
| Detoxification of reactive oxygen species 4 10 -0.1845808606124966 0.8535577989986562 |
| Pi 3k cascade fgfr2 1 2 -0.1834755644885843 0.854424890032695 |
| Frs mediated fgfr1 signaling 1 2 -0.1834755644885843 0.854424890032695 |
| Pi 3k cascade fgfr1 1 2 -0.1834755644885843 0.854424890032695 |
| Frs mediated fgfr3 signaling 1 2 -0.1834755644885843 0.854424890032695 |
| Pi 3k cascade fgfr3 1 2 -0.1834755644885843 0.854424890032695 |
| Activated ntrk2 signals through frs2 and frs3 1 2 -0.1834755644885843 0.854424890032695 |
| Met activates ptpn11 1 2 -0.1834755644885843 0.854424890032695 |
| Pi 3k cascade fgfr4 1 2 -0.1834755644885843 0.854424890032695 |
| Frs mediated fgfr2 signaling 1 2 -0.1834755644885843 0.854424890032695 |
| Frs mediated fgfr4 signaling 1 2 -0.1834755644885843 0.854424890032695 |
| Stat5 activation downstream of flt3 itd mutants 1 2 -0.1834755644885843 0.854424890032695 |
| Stat5 activation 1 2 -0.1834755644885843 0.854424890032695 |
| Signaling by flt3 itd and tkd mutants 1 2 -0.1834755644885843 0.854424890032695 |
| Tie2 signaling 1 2 -0.1834755644885843 0.854424890032695 |
| Maturation of sars cov 1 spike protein 1 4 -0.183428603196432 0.8544617344829966 |
| Hdr through mmej alt nhej 4 8 0.1824904176864625 0.8551978736761294 |
| Dna strand elongation 11 30 -0.1819797862460097 0.8555985892562221 |
| Glycogen synthesis 3 6 -0.1814911502124701 0.8559820789138928 |
| Signaling by notch1 2 12 -0.1811837883849619 0.8562233190009576 |
| Abortive elongation of hiv 1 transcript in the absence of tat 2 17 -0.1800457285330587 0.8571166685681537 |
| Constitutive signaling by ligand responsive egfr cancer variants 2 6 -0.1795084941448943 0.857538448296554 |
| Signaling by egfr in cancer 2 6 -0.1795084941448943 0.857538448296554 |
| Constitutive signaling by egfrviii 2 6 -0.1795084941448943 0.857538448296554 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 5 7 -0.1778108575812962 0.858871520116625 |
| Prevention of phagosomal lysosomal fusion 3 4 -0.1772449173331647 0.8593160152307178 |
| Nuclear import of rev protein 8 30 0.175673672776522 0.8605503196928264 |
| Atf4 activates genes in response to endoplasmic reticulum stress 5 13 -0.1754981530427493 0.8606882219178111 |
| Vldlr internalisation and degradation 1 7 -0.1739799691530033 0.8618812044435016 |
| Wnt5a dependent internalization of fzd2 fzd5 and ror2 1 7 -0.1739799691530033 0.8618812044435016 |
| Galactose catabolism 1 4 0.1724163968724264 0.8631101823702354 |
| Notch4 intracellular domain regulates transcription 1 2 -0.1714183351544524 0.8638948387842105 |
| Muscle contraction 9 29 -0.1706097743606759 0.8645306117877332 |
| Rab regulation of trafficking 13 41 -0.1683358570622225 0.8663190664804163 |
| P130cas linkage to mapk signaling for integrins 1 2 -0.1653740699933213 0.8686495617994214 |
| Chromosome maintenance 16 51 -0.1647391652247594 0.8691492887269989 |
| Disinhibition of snare formation 1 2 -0.1645976904441361 0.8692606491809904 |
| Ptk6 regulates proteins involved in rna processing 1 2 0.1643580719528681 0.869449268386534 |
| Gp1b ix v activation signalling 1 2 0.1635558360891504 0.8700808141069729 |
| Attachment and entry 1 1 -0.1633091447256341 0.8702750341134098 |
| Protein ubiquitination 4 24 -0.1632057512301858 0.8703564380964222 |
| Spry regulation of fgf signaling 2 6 -0.1630979461014459 0.8704413169185927 |
| Negative regulation of fgfr3 signaling 2 6 -0.1630979461014459 0.8704413169185927 |
| Negative regulation of fgfr4 signaling 2 6 -0.1630979461014459 0.8704413169185927 |
| Negative regulation of fgfr1 signaling 2 6 -0.1630979461014459 0.8704413169185927 |
| Negative regulation of fgfr2 signaling 2 6 -0.1630979461014459 0.8704413169185927 |
| Signaling by insulin receptor 4 16 -0.1623063814424044 0.8710645896490898 |
| Pd 1 signaling 0 2 0.1620554958806865 0.8712621519973909 |
| Regulation of tp53 activity through methylation 5 6 0.161288982824436 0.8718658000892616 |
| Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway 1 1 -0.1611036882212157 0.87201173541147 |
| Interleukin 17 signaling 3 19 -0.1609427630520537 0.8721384812583663 |
| Ionotropic activity of kainate receptors 2 2 -0.1594892372940807 0.8732834371806373 |
| Nrcam interactions 2 2 -0.1594892372940807 0.8732834371806373 |
| Dopamine neurotransmitter release cycle 1 2 0.1584176120810098 0.8741277365805582 |
| Cooperation of prefoldin and tric cct in actin and tubulin folding 5 16 -0.1568796262162971 0.875339716946786 |
| Downregulation of erbb2 signaling 4 8 -0.1565711200883247 0.8755828646106749 |
| Factors involved in megakaryocyte development and platelet production 13 49 0.1557303616557887 0.8762455639963105 |
| Polb dependent long patch base excision repair 2 7 0.1551769403413618 0.8766818270074865 |
| Gap junction degradation 3 5 0.1544232842509879 0.8772759956786647 |
| G0 and early g1 4 9 -0.1502406261723801 0.8805747745844563 |
| Rhobtb1 gtpase cycle 5 19 -0.1490323476414759 0.8815281082585984 |
| Synthesis secretion and deacylation of ghrelin 2 3 0.1483192816102269 0.8820907991304656 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 2 3 0.1483192816102269 0.8820907991304656 |
| Laminin interactions 1 2 -0.1482196453023445 0.8821694283488233 |
| Met activates ptk2 signaling 1 2 -0.1482196453023445 0.8821694283488233 |
| Recycling of eif2 gdp 1 8 0.1477855140838523 0.8825120418842387 |
| Dag and ip3 signaling 2 10 -0.1474308414077739 0.8827919635727268 |
| Innate immune system 65 304 -0.143410349346631 0.8859661098645171 |
| Arms mediated activation 2 2 -0.1433542023063469 0.8860104505816533 |
| Death receptor signalling 8 29 -0.1424625976472387 0.8867146207452274 |
| Activation of nmda receptors and postsynaptic events 6 25 -0.1412451455783812 0.8876762825283777 |
| Nef mediated downregulation of mhc class i complex cell surface expression 1 5 -0.1377678982398807 0.8904238558802886 |
| Signaling by fgfr1 2 7 -0.137639797965608 0.8905251006271486 |
| Signaling by fgfr3 2 7 -0.137639797965608 0.8905251006271486 |
| Signaling by fgfr4 2 7 -0.137639797965608 0.8905251006271486 |
| Toll like receptor cascades 4 31 -0.1367364048885979 0.8912391528395895 |
| Regulation of pyruvate dehydrogenase pdh complex 2 8 -0.136332880574381 0.8915581316037506 |
| Neuronal system 12 55 0.1348566107262537 0.8927252457078425 |
| Circadian clock 5 13 0.1348524461552452 0.8927285384774828 |
| Dna replication 10 96 0.1346382766015586 0.8928978767788955 |
| Organic anion transporters 0 2 0.1341367992265783 0.8932944009988493 |
| Developmental biology 66 277 -0.1335027156275181 0.8937958167364881 |
| Protein methylation 1 7 0.1308119427296325 0.8959240752501767 |
| Vesicle mediated transport 59 268 -0.1302034359955405 0.8964054761924816 |
| Traf6 mediated irf7 activation 3 3 -0.1294630350632149 0.8969912724995506 |
| Metabolism of nitric oxide nos3 activation and regulation 1 7 0.1289369642486153 0.8974075275391027 |
| Membrane trafficking 57 260 -0.1272719289853713 0.8987251770311535 |
| Translation of sars cov 1 structural proteins 1 5 -0.1265447784024929 0.8993007058745637 |
| Viral messenger rna synthesis 10 35 0.1259711842041381 0.899754734510015 |
| Interferon gamma signaling 3 14 0.1257696469949732 0.8999142691361046 |
| Runx1 interacts with co factors whose precise effect on runx1 targets is not known 6 16 -0.1251582419555811 0.9003982753199367 |
| Hemostasis 22 132 -0.125101792714594 0.9004429640672225 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 3 4 0.1240092161600829 0.901307977952234 |
| Zbp1 dai mediated induction of type i ifns 1 6 -0.1231319253830317 0.9020026308332324 |
| Rip mediated nfkb activation via zbp1 1 6 -0.1231319253830317 0.9020026308332324 |
| Slbp dependent processing of replication dependent histone pre mrnas 1 4 -0.1230514089813036 0.9020663887766986 |
| Synthesis of very long chain fatty acyl coas 4 9 -0.122190573881336 0.9027480914689864 |
| Cyclin d associated events in g1 5 11 0.1219248258028926 0.902958554158388 |
| Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 1 11 -0.1216126173563892 0.9032058204587758 |
| Trp channels 1 1 -0.1215370667040721 0.9032656573121884 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 1 12 0.1208457627151832 0.90381320228547 |
| The citric acid tca cycle and respiratory electron transport 13 95 0.1196598802013467 0.9047525828957812 |
| Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 1 6 -0.1193823614073922 0.9049724349087944 |
| Regulation of bach1 activity 2 4 -0.1191540475761721 0.9051533119243308 |
| Dna replication initiation 0 7 0.1188295372639449 0.9054104071217182 |
| Aurka activation by tpx2 8 33 0.1185295030343899 0.9056481198203964 |
| Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis 2 2 -0.1166683965263982 0.907122835123252 |
| G2 m dna damage checkpoint 12 38 0.1165878766471266 0.9071866452361635 |
| Formation of the early elongation complex 2 20 -0.1164478936290062 0.9072975799155264 |
| Mapk3 erk1 activation 0 6 0.116259645821344 0.9074467666491016 |
| Heme biosynthesis 1 5 0.1156509503790242 0.9079291812269874 |
| Apoptosis 39 94 -0.1151774301520393 0.9083044877362764 |
| Ikba variant leads to eda id 1 3 -0.1145628372192256 0.90879163730999 |
| Extracellular matrix organization 4 28 -0.1140978514591542 0.909160225390037 |
| Transport of mature mrnas derived from intronless transcripts 12 36 0.1137749958679988 0.909416160267138 |
| Nervous system development 54 223 -0.1137274940725947 0.9094538168010512 |
| Ptk6 regulates cell cycle 0 2 0.1135539025556875 0.9095914313257388 |
| Interactions of rev with host cellular proteins 8 33 0.113080925158324 0.9099663975006484 |
| Reduction of cytosolic ca levels 2 4 0.1122063284497721 0.9106598114831336 |
| Insulin processing 3 10 -0.1109129891552627 0.9116853452999358 |
| Trafficking and processing of endosomal tlr 0 2 0.1104819317217658 0.9120271785391244 |
| Atf6 atf6 alpha activates chaperone genes 2 2 -0.1096523201933258 0.9126851152786204 |
| Atf6 atf6 alpha activates chaperones 2 2 -0.1096523201933258 0.9126851152786204 |
| Glyoxylate metabolism and glycine degradation 5 13 -0.1092512885242803 0.9130031813686156 |
| Estrogen dependent nuclear events downstream of esr membrane signaling 2 5 -0.1086726246026289 0.9134621556342948 |
| Regulation of tp53 activity through acetylation 3 13 -0.1082344247206832 0.913809738366062 |
| The role of nef in hiv 1 replication and disease pathogenesis 1 13 -0.1065268503613065 0.9151643531028408 |
| Telomere c strand lagging strand synthesis 3 23 0.1057651123255309 0.9157687178189275 |
| Response of eif2ak1 hri to heme deficiency 0 4 0.1036783453730763 0.9174246119165844 |
| Transcriptional regulation by e2f6 3 10 0.1036601701921624 0.9174390358946788 |
| Ikk complex recruitment mediated by rip1 1 5 0.1034457563171045 0.9176091986188476 |
| Tp53 regulates transcription of caspase activators and caspases 2 2 -0.1028441651671512 0.9180866523478683 |
| Tp53 regulates transcription of genes involved in cytochrome c release 2 2 -0.1028441651671512 0.9180866523478683 |
| Processive synthesis on the lagging strand 5 14 -0.0996555902624864 0.9206177587945286 |
| Host interactions of hiv factors 11 95 0.0986440071770912 0.921420927718452 |
| Rmts methylate histone arginines 5 21 -0.0973925499255309 0.9224146609021764 |
| Pyrimidine salvage 3 4 0.0953039720701083 0.9240733877616744 |
| Interactions of vpr with host cellular proteins 20 33 0.0950860372464202 0.9242464884857422 |
| Tp53 regulates transcription of cell cycle genes 7 17 -0.0946497433813189 0.9245930376511338 |
| Aggrephagy 1 16 -0.0941101210821615 0.9250216806055696 |
| Nuclear events stimulated by alk signaling in cancer 4 12 0.0935955303024856 0.9254304603309468 |
| Activation of kainate receptors upon glutamate binding 0 3 0.0934587402589247 0.9255391266838844 |
| Asparagine n linked glycosylation 26 127 -0.0930454749164503 0.9258674341365088 |
| Regulation of plk1 activity at g2 m transition 8 38 0.0923784058446743 0.9263973956953722 |
| Perk regulates gene expression 5 16 -0.0921757235237422 0.9265584257382145 |
| Trafficking of ampa receptors 2 11 -0.0903206207472425 0.9280324341349926 |
| Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 1 5 -0.0895023137472837 0.928682714860776 |
| Glucagon signaling in metabolic regulation 4 5 -0.0892841787921224 0.928856067344664 |
| Vasopressin regulates renal water homeostasis via aquaporins 4 5 -0.0892841787921224 0.928856067344664 |
| Plasma lipoprotein assembly 1 3 -0.0889601388563002 0.9291135890554612 |
| Regulation of gene expression in beta cells 0 2 0.0879634401568505 0.929905733994812 |
| Transcription coupled nucleotide excision repair tc ner 7 48 0.0872587364079778 0.930465852442762 |
| Mrna splicing 24 150 -0.0870728845424943 0.9306135785069334 |
| Transport to the golgi and subsequent modification 16 84 -0.0868782628896916 0.9307682778795978 |
| G alpha z signalling events 1 6 0.0862233524020978 0.9312888673021752 |
| Fgfr2 alternative splicing 4 18 0.0856861957806942 0.9317158759372924 |
| Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 7 50 -0.0833547404043035 0.9335694751425208 |
| Abacavir transport and metabolism 0 2 0.0831904423899125 0.933700112265212 |
| Negative regulation of the pi3k akt network 3 13 0.082883843790262 0.9339439006220724 |
| Pyruvate metabolism and citric acid tca cycle 3 36 0.0815876122888099 0.9349746524128716 |
| Bile acid and bile salt metabolism 1 6 0.0813868027331175 0.9351343441857812 |
| Synthesis of bile acids and bile salts 1 6 0.0813868027331175 0.9351343441857812 |
| Fructose metabolism 2 2 -0.0806445594697576 0.9357246282535884 |
| Peptide hormone metabolism 2 15 0.0804393811560937 0.935887806732584 |
| Runx2 regulates genes involved in cell migration 0 2 0.0802520023703923 0.9360368315856152 |
| Cytosolic sulfonation of small molecules 3 6 0.0793769646228394 0.936732790387059 |
| Positive epigenetic regulation of rrna expression 4 32 -0.0791190447903109 0.9369379354455863 |
| Activation of smo 0 3 0.078976096880222 0.9370516355917264 |
| Activated ntrk2 signals through cdk5 0 2 0.076009406422173 0.9394116146069992 |
| Sensory processing of sound 8 20 0.0758754322995022 0.9395182026872544 |
| Adora2b mediated anti inflammatory cytokines production 1 9 -0.0754668444524438 0.9398432765800409 |
| Rna polymerase i transcription 4 28 -0.075458414878781 0.9398499832834836 |
| Interferon alpha beta signaling 3 12 -0.0751240935604819 0.94011597809888 |
| Nod1 2 signaling pathway 1 8 -0.0745526641687442 0.940570637772464 |
| Cytosolic trna aminoacylation 23 23 -0.0735363047246688 0.941379355273504 |
| Scavenging by class f receptors 3 4 0.0716821683062019 0.942854847282083 |
| Synthesis of ip2 ip and ins in the cytosol 1 3 -0.0714420743558255 0.9430459246441428 |
| Formation of tc ner pre incision complex 3 28 -0.0708327873966008 0.9435308367837484 |
| Epha mediated growth cone collapse 3 11 0.0685888895771345 0.9453168628724892 |
| Er to golgi anterograde transport 14 81 -0.0661555686984687 0.9472539702817816 |
| Anti inflammatory response favouring leishmania parasite infection 2 16 -0.065945028676517 0.9474215908810166 |
| Aquaporin mediated transport 1 6 -0.0653687612261843 0.9478803957951676 |
| Sars cov 2 infection 4 23 -0.0645458372378016 0.9485356103398346 |
| Recruitment of mitotic centrosome proteins and complexes 7 33 0.0639406380787787 0.9490174939574628 |
| Copi mediated anterograde transport 6 58 0.062452418841614 0.950202552192888 |
| Darpp 32 events 6 10 -0.0617242855631362 0.9507823997578012 |
| Hiv elongation arrest and recovery 5 23 -0.0610506071205977 0.9513189055337964 |
| Formation of rna pol ii elongation complex 4 34 -0.0606667551437948 0.9516246084452982 |
| Integration of energy metabolism 6 25 -0.0605476641233374 0.951719454974989 |
| Signaling by ntrk2 trkb 1 5 -0.0593980985657458 0.9526350275121058 |
| Mitochondrial biogenesis 6 35 0.0588497682655584 0.9530717677766414 |
| Notch1 intracellular domain regulates transcription 3 9 0.0580052622026549 0.9537444369548688 |
| Telomere extension by telomerase 4 12 -0.0574089330733115 0.9542194471765412 |
| Acyl chain remodeling of cl 1 2 -0.0565970952302502 0.9548661485082752 |
| Nucleotide excision repair 8 58 0.0561360938648779 0.955233390513968 |
| Base excision repair 4 31 0.0553532282646279 0.9558570571087516 |
| Transport of vitamins nucleosides and related molecules 6 6 -0.0548955771105425 0.9562216555220582 |
| Thrombin signalling through proteinase activated receptors pars 3 5 -0.0542451168166696 0.9567398755544824 |
| Clec7a inflammasome pathway 0 3 0.0540094642005383 0.9569276239074882 |
| Hsf1 activation 4 14 -0.053172351643625 0.957594584634128 |
| Synthesis of pips at the early endosome membrane 3 6 0.0526293394730675 0.9580272398396108 |
| Dex h box helicases activate type i ifn and inflammatory cytokines production 2 3 0.0520995136455731 0.9584494004961446 |
| Regulation of pten gene transcription 4 21 0.0512269924856186 0.9591446431839789 |
| Inla mediated entry of listeria monocytogenes into host cells 1 2 0.050686432660818 0.959575387920962 |
| Rhobtb gtpase cycle 7 28 -0.050330784772905 0.9598587921486296 |
| Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 1 3 -0.0502587558537301 0.9599161902691224 |
| Meiotic synapsis 5 15 0.0496723896328701 0.9603834591707716 |
| Rho gtpase effectors 24 124 0.049608574719256 0.9604343134095346 |
| Hiv transcription elongation 2 28 -0.0489016161971172 0.9609977008659604 |
| Protein folding 7 35 -0.0487281686813728 0.9611359271732608 |
| Trna processing in the nucleus 7 42 0.0480344425343424 0.9616887931048616 |
| Pecam1 interactions 3 4 0.0480321570620633 0.9616906145454828 |
| Sumoylation of intracellular receptors 0 2 0.0471729158848525 0.9623754134763474 |
| Prolactin receptor signaling 2 3 0.0461343170354052 0.96320319407861 |
| Interleukin 7 signaling 0 3 0.0460584585038873 0.9632636561583224 |
| Activation of the pre replicative complex 2 24 0.0439492955324385 0.9649448210830378 |
| Interaction between l1 and ankyrins 3 4 0.0422644357557643 0.9662878960951344 |
| Reproduction 6 27 0.0411039650201414 0.9672130136478124 |
| Meiosis 6 27 0.0411039650201414 0.9672130136478124 |
| Intrinsic pathway of fibrin clot formation 1 2 -0.0404938652258364 0.9676993978724092 |
| Rhou gtpase cycle 6 20 0.0391950058870958 0.968734915303499 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 3 3 -0.0388946426593246 0.9689743878773176 |
| Recruitment of numa to mitotic centrosomes 7 37 0.0387847280212424 0.969062020946902 |
| Sumoylation 16 79 0.0371321909593487 0.9703796050459276 |
| Synthesis of pips at the plasma membrane 2 12 0.0364094656958119 0.9709558666512792 |
| Folding of actin by cct tric 2 8 -0.0358817986855187 0.9713766090659685 |
| Tp53 regulates transcription of death receptors and ligands 1 2 0.0351052525230543 0.9719958130877064 |
| Erythropoietin activates phospholipase c gamma plcg 0 2 0.0347154771180571 0.9723066194108008 |
| Dual incision in tc ner 4 36 0.0340917802729673 0.972803963068572 |
| Synthesis of ip3 and ip4 in the cytosol 1 2 0.0339165202232315 0.972943719533883 |
| Receptor type tyrosine protein phosphatases 1 2 0.0339055588839379 0.9729524603900146 |
| Processing and activation of sumo 0 2 0.0337883169442805 0.973045952355243 |
| Sumo is transferred from e1 to e2 ube2i ubc9 0 2 0.0337883169442805 0.973045952355243 |
| Sumo is conjugated to e1 uba2 sae1 0 2 0.0337883169442805 0.973045952355243 |
| Fbxw7 mutants and notch1 in cancer 0 2 0.0337470256513065 0.9730788792625022 |
| Fcgr activation 0 2 0.0336876048823852 0.9731262632345437 |
| Organelle biogenesis and maintenance 22 100 0.0327014577989231 0.9739126613589324 |
| Signaling by nodal 1 2 -0.0322111708048115 0.9743036477887748 |
| Signaling by activin 1 2 -0.0322111708048115 0.9743036477887748 |
| Erks are inactivated 1 7 -0.0280004394766079 0.9776618006337314 |
| Ire1alpha activates chaperones 11 25 0.0270527971847139 0.9784176233560776 |
| Activation of atr in response to replication stress 2 23 0.0266898256597942 0.978707128190365 |
| Diseases of immune system 1 5 -0.0249603478702065 0.9800865915620824 |
| Cellular response to starvation 22 87 0.0249057098316075 0.9801301728611158 |
| Rhobtb2 gtpase cycle 8 19 0.0242855843899601 0.980624811731347 |
| Trna modification in the nucleus and cytosol 3 17 0.0233550843162427 0.9813670327461574 |
| Processive synthesis on the c strand of the telomere 2 12 0.0228491189183022 0.9817706270062384 |
| Signaling by fgfr2 6 25 0.0227332005168471 0.9818630924909066 |
| Signaling by fgfr 6 25 0.0227332005168471 0.9818630924909066 |
| Hcmv late events 8 36 0.0206399864539006 0.9835328426745358 |
| Jnk c jun kinases phosphorylation and activation mediated by activated human tak1 2 2 -0.0204748162960009 0.983664601549243 |
| Inhibition of replication initiation of damaged dna by rb1 e2f1 2 6 -0.0199837383713975 0.9840563448759794 |
| Synthesis of udp n acetyl glucosamine 5 5 -0.0190131614637829 0.9848306059782724 |
| Glucuronidation 2 3 -0.0170506481137919 0.9863962102809064 |
| Transcription of e2f targets under negative control by dream complex 3 6 0.0161097527828138 0.9871468329298234 |
| Attenuation phase 10 11 0.0156383685763187 0.9875228957226836 |
| Translocation of slc2a4 glut4 to the plasma membrane 3 39 0.0131615519387952 0.989498904090632 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 5 5 -0.0128543015149673 0.9897440337195418 |
| Beta oxidation of octanoyl coa to hexanoyl coa 5 5 -0.0128543015149673 0.9897440337195418 |
| Beta oxidation of pristanoyl coa 3 4 -0.0119256828542043 0.9904849073165783 |
| Inositol phosphate metabolism 1 5 -0.0109964151134526 0.991226306977988 |
| Translation of sars cov 2 structural proteins 2 16 0.0106138552115437 0.9915315277975124 |
| Signaling by retinoic acid 5 13 0.0098054079481873 0.992176541751704 |
| Hcmv early events 12 47 0.0097727044905324 0.9922026340854636 |
| Tryptophan catabolism 2 2 -0.0087939754787759 0.9929835131730264 |
| Glycolysis 12 50 0.0081156811992644 0.993524694352679 |
| Deadenylation dependent mrna decay 8 42 0.0080903282880867 0.9935449223849946 |
| Runx1 regulates estrogen receptor mediated transcription 1 2 -0.0079057924901931 0.9936921559395756 |
| Signaling by interleukins 12 117 0.0070827405641447 0.994348837904362 |
| Global genome nucleotide excision repair gg ner 3 42 0.0062096067497639 0.9950454824861116 |
| Neurotransmitter receptors and postsynaptic signal transmission 9 36 0.0011313710469168 0.9990972967017024 |
| Tp53 regulates transcription of cell death genes 5 5 -0.0007015001797479 0.9994402838830848 |
| Metabolism of lipids 39 195 0.0 1.0 |
| M phase 55 203 0.0 1.0 |
| Mhc class ii antigen presentation 10 55 0.0 1.0 |
| E3 ubiquitin ligases ubiquitinate target proteins 1 15 0.0 1.0 |
| Rna polymerase ii transcribes snrna genes 10 30 0.0 1.0 |
| Rna polymerase i transcription initiation 4 23 0.0 1.0 |
| Eukaryotic translation elongation 23 76 0.0 1.0 |
| Selenoamino acid metabolism 22 87 0.0 1.0 |
| Tp53 regulates transcription of dna repair genes 10 33 0.0 1.0 |
| Free fatty acids regulate insulin secretion 2 2 0.0 1.0 |
| Rna polymerase ii transcription 79 337 0.0 1.0 |
| Apoptotic cleavage of cellular proteins 0 23 0.0 1.0 |
| Rrna modification in the nucleus and cytosol 4 58 0.0 1.0 |
| Mitotic metaphase and anaphase 39 144 0.0 1.0 |
| Post translational protein modification 52 416 0.0 1.0 |
| Rhov gtpase cycle 5 22 0.0 1.0 |
| Translation 30 220 0.0 1.0 |
| Signaling by rho gtpases miro gtpases and rhobtb3 57 277 0.0 1.0 |
| Hiv life cycle 26 84 0.0 1.0 |
| Cell cycle 93 323 0.0 1.0 |
| Mrna splicing minor pathway 7 35 0.0 1.0 |
| Signaling by receptor tyrosine kinases 23 130 0.0 1.0 |
| Srp dependent cotranslational protein targeting to membrane 28 91 0.0 1.0 |
| Metabolism of amino acids and derivatives 17 192 0.0 1.0 |
| Rrna processing 40 171 0.0 1.0 |
| Hiv infection 16 141 0.0 1.0 |
| Acyl chain remodelling of pc 2 2 0.0 1.0 |
| Regulation of expression of slits and robos 11 125 0.0 1.0 |
| Rho gtpase cycle 16 175 0.0 1.0 |
| Cell cycle checkpoints 43 155 0.0 1.0 |
| Eukaryotic translation initiation 27 100 0.0 1.0 |
| Extension of telomeres 4 34 0.0 1.0 |
| Cell cycle mitotic 76 271 0.0 1.0 |
| Rhod gtpase cycle 3 32 0.0 1.0 |
| Nef and signal transduction 2 2 0.0 1.0 |
| Glucose metabolism 14 61 0.0 1.0 |
| Retrograde neurotrophin signalling 4 8 0.0 1.0 |
| Ephb mediated forward signaling 3 17 0.0 1.0 |
| Aflatoxin activation and detoxification 3 3 0.0 1.0 |
| Cellular responses to stimuli 44 335 0.0 1.0 |
| Metabolism of rna 86 487 0.0 1.0 |
| Transport of small molecules 28 157 0.0 1.0 |
| Adaptive immune system 20 200 0.0 1.0 |
| Uptake and function of diphtheria toxin 1 4 0.0 1.0 |
| Cytokine signaling in immune system 23 185 0.0 1.0 |
| Response of eif2ak4 gcn2 to amino acid deficiency 23 76 0.0 1.0 |
| Influenza infection 40 124 0.0 1.0 |
| Unfolded protein response upr 6 43 0.0 1.0 |
| Programmed cell death 6 107 0.0 1.0 |
| Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 3 33 0.0 1.0 |
| Transcriptional regulation by tp53 33 131 0.0 1.0 |
| Signaling by robo receptors 12 143 0.0 1.0 |
| Trna aminoacylation 13 36 0.0 1.0 |
| Transcriptional regulation by small rnas 10 39 0.0 1.0 |
| Processing of capped intron containing pre mrna 20 191 0.0 1.0 |
| Signaling by ptk6 1 15 0.0 1.0 |
| Transcription of the hiv genome 11 32 0.0 1.0 |
| Wax and plasmalogen biosynthesis 1 4 0.0 1.0 |
| Rna polymerase i transcription termination 2 13 0.0 1.0 |
| Association of tric cct with target proteins during biosynthesis 18 19 0.0 1.0 |
| Signaling by leptin 2 2 0.0 1.0 |
| Opioid signalling 8 20 0.0 1.0 |
| Role of lat2 ntal lab on calcium mobilization 1 2 0.0 1.0 |
| Traf3 dependent irf activation pathway 2 2 0.0 1.0 |
| Nonsense mediated decay nmd 26 89 0.0 1.0 |
| Signaling by alk in cancer 9 35 0.0 1.0 |
| Post chaperonin tubulin folding pathway 0 10 0.0 1.0 |
| Dna repair 28 125 0.0 1.0 |
| Pre notch processing in the endoplasmic reticulum 1 2 0.0 1.0 |
| Infectious disease 44 363 0.0 1.0 |
| Diseases of signal transduction by growth factor receptors and second messengers 29 150 0.0 1.0 |
| Neurotransmitter clearance 1 2 0.0 1.0 |
| Hcmv infection 7 56 0.0 1.0 |
| Chromatin modifying enzymes 16 79 0.0 1.0 |
| Formation of tubulin folding intermediates by cct tric 5 13 0.0 1.0 |
| Transport of mature transcript to cytoplasm 15 65 0.0 1.0 |
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