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-1.4402973838865278], ["Q9BQ39", -1.4402973838865278], ["Q9BTC0", -1.4402973838865278], ["Q9NQS7", -1.4402973838865278], ["Q9NW13", -1.4402973838865278], ["Q9NXF1", -1.4402973838865278], ["Q9Y2B0", -1.4402973838865278], ["O15400", -1.4973219804574316], ["O43390", -1.4973219804574316], ["O75879", -1.4973219804574316], ["O75915", -1.4973219804574316], ["P05387", -1.4973219804574316], ["P14314", -1.4973219804574316], ["P14625", -1.4973219804574316], ["P30837", -1.4973219804574316], ["P31323", -1.4973219804574316], ["P84090", -1.4973219804574316], ["Q02040", -1.4973219804574316], ["Q8IXT5", -1.4973219804574316], ["Q8TDD1", -1.4973219804574316], ["Q9UHA3", -1.4973219804574316], ["Q9UIF9", -1.4973219804574316], ["Q9Y2Q9", -1.4973219804574316], ["Q9Y3A4", -1.4973219804574316], ["O94925", -1.5547521709042478], ["P07237", -1.5547521709042478], ["P12532", -1.5547521709042478], ["P22307", -1.5547521709042478], ["P22626", -1.5547521709042478], ["P28370", -1.5547521709042478], ["P30043", -1.5547521709042478], ["P45973", -1.5547521709042478], ["Q13435", -1.5547521709042478], ["Q14146", -1.5547521709042478], ["Q96CP7", -1.5547521709042478], ["Q96DE5", -1.5547521709042478], ["O15226", -1.612593706829535], ["P62312", -1.612593706829535], ["P82979", -1.612593706829535], ["Q14149", -1.612593706829535], ["Q86UP2", -1.612593706829535], ["Q96K76", -1.612593706829535], ["Q96KM6", -1.612593706829535], ["Q9NR30", -1.612593706829535], ["Q9UMX5", -1.612593706829535], ["Q9UQ35", -1.612593706829535], ["Q9Y5Q9", -1.612593706829535], ["O75376", -1.6708524626254244], ["P23246", -1.6708524626254244], ["P46977", -1.6708524626254244], ["Q00839", -1.6708524626254244], ["Q02241", -1.6708524626254244], ["Q14156", -1.6708524626254244], ["Q15269", -1.6708524626254244], ["Q6KC79", -1.6708524626254244], ["Q8WTT2", -1.6708524626254244], ["Q99590", -1.6708524626254244], ["Q9BQG0", -1.6708524626254244], ["Q9H307", -1.6708524626254244], ["Q9NPJ3", -1.6708524626254244], ["Q9Y3T9", -1.6708524626254244], ["O94804", -1.7295344389876053], ["P11387", -1.7295344389876053], ["P14866", -1.7295344389876053], ["P55084", -1.7295344389876053], ["P61803", -1.7295344389876053], ["Q8TB37", -1.7295344389876053], ["Q8TDW0", -1.7295344389876053], ["Q8WWQ0", -1.7295344389876053], ["Q99623", -1.7295344389876053], ["Q9NY61", -1.7295344389876053], ["Q9UN81", -1.7295344389876053], ["O14925", -1.7886457665558944], ["O60346", -1.7886457665558944], ["O75691", -1.7886457665558944], ["P08174", -1.7886457665558944], ["P10253", -1.7886457665558944], ["P10412", -1.7886457665558944], ["P48651", -1.7886457665558944], ["Q02880", -1.7886457665558944], ["Q14690", -1.7886457665558944], ["Q14696", -1.7886457665558944], ["Q5UIP0", -1.7886457665558944], ["Q8IY81", -1.7886457665558944], ["Q9Y4L1", -1.7886457665558944], ["O75352", -1.8481927096869457], ["P16219", -1.8481927096869457], ["P53985", -1.8481927096869457], ["Q00059", -1.8481927096869457], ["Q8IX12", -1.8481927096869457], ["Q8N653", -1.8481927096869457], ["Q8NI36", -1.8481927096869457], ["Q96L73", -1.8481927096869457], ["Q9UKM9", -1.8481927096869457], ["O43399", -1.9081816703644308], ["P06576", -1.9081816703644308], ["P09012", -1.9081816703644308], ["P11388", -1.9081816703644308], ["P13667", -1.9081816703644308], ["P46013", -1.9081816703644308], ["Q12769", -1.9081816703644308], ["Q15287", -1.9081816703644308], ["Q15293", -1.9081816703644308], ["Q15459", -1.9081816703644308], ["Q8IUH3", -1.9081816703644308], ["Q8NDT2", -1.9081816703644308], ["Q96T23", -1.9081816703644308], ["O00566", -1.9686191922532723], ["P30414", -1.9686191922532723], ["P36542", -1.9686191922532723], ["Q08211", -1.9686191922532723], ["Q13151", -1.9686191922532723], ["Q7RTV0", -1.9686191922532723], ["Q86Y39", -1.9686191922532723], ["Q8IY17", -1.9686191922532723], ["Q9H5V9", -1.9686191922532723], ["Q9NZW5", -1.9686191922532723], ["Q9P2E9", -1.9686191922532723], ["P09234", -2.029511964903985], ["Q13123", -2.029511964903985], ["Q15424", -2.029511964903985], ["Q15428", -2.029511964903985], ["Q8NB14", -2.029511964903985], ["Q96QD8", -2.029511964903985], ["P35637", -2.0908668281141427], ["P50416", -2.0908668281141427], ["P54819", -2.0908668281141427], ["Q8NI27", -2.0908668281141427], ["Q9UKG1", -2.0908668281141427], ["O94762", -2.152690776453799], ["P38159", -2.152690776453799], ["P82650", -2.2149909639620957], ["Q14978", -2.2149909639620957], ["Q16718", -2.2149909639620957], ["Q5T2R2", -2.2149909639620957], ["Q7Z5G4", -2.2149909639620957], ["Q92804", -2.2149909639620957], ["Q96GC9", -2.2149909639620957], ["Q96HP4", -2.2149909639620957], ["Q96SB8", -2.2149909639620957], ["Q9Y3B7", -2.2149909639620957], ["Q13523", -2.2777747090238187], ["Q5BKZ1", -2.2777747090238187], ["Q96FK6", -2.2777747090238187], ["Q5GLZ8", -2.3410494994330877], ["Q96MU7", -2.3410494994330877], ["Q9Y3C6", -2.40482299765352], ["Q86UT6", -2.4691030462841184], ["P06748", -2.5338976737399093], ["Q9BSY4", -2.5338976737399093], ["Q13011", -2.665063743544366], ["Q5ZPR3", -2.665063743544366], ["Q86VM9", -2.73145222615574], ["P36639", -2.7983893811587794], ["Q8IXM2", -2.7983893811587794], ["Q9Y4F1", -2.7983893811587794], ["O00763", -2.933946137358419], ["Q9C0E2", -2.933946137358419], ["Q9NRX2", -3.0025845231695865], ["P31942", -3.2120574693012034], ["Q12872", -3.2120574693012034], ["Q07021", -3.2831019048412227], ["P07910", -3.4270853312340446], ["P22392", -3.4270853312340446], ["O94842", -3.5000467778315163], ["Q96RQ3", -3.6479675527937547], ["P05165", -3.722951203678394], ["Q15006", -3.7986338038751826], ["P04179", -3.8750283713129074], ["O14657", -4.10861962731828], ["P11498", -4.349123983374581], ["Q96C90", -4.430899379576358], ["Q15041", -4.5135053043528055], ["P52815", -4.681253781219751], ["Q13085", -5.664516587193105], ["P19338", -6.244151920620782], ["P20700", -11.70723971066986]]}, "terms": {"Processing of capped intron containing pre mrna": {"direction": "dw", "overlap": {"value": 106, "mean": 61.44660194174757, "std": 22.544983363510543, "bin": {}}, "setsize": {"value": 179, "mean": 182.83009708737865, "std": 8.980305689776722, "bin": {}}, "score": {"value": -6.599736260915687, "mean": -0.6525536485470969, "std": 1.3401481761909957, "bin": {}}, "pval": {"value": 4.1188986226846255e-11, "mean": 0.5600064525169441, "std": 0.3579178268520561, "bin": {}}, "signature_idxs": {"edge": [3084, 2533, 3077, 3076, 2602, 3089, 3102, 2595, 2581, 3128, 2588, 3139, 3142, 3140, 2655, 3135, 2653, 3151, 2664, 2666, 3150, 3149, 2672, 3157, 3160, 3166, 3163, 3169, 2644, 3185, 3201, 2687, 2682, 2690, 2750, 2746, 2759, 2742, 2732, 2782, 2791, 2779, 2766, 2769, 2242, 2241, 2776, 2239, 2329, 2325, 2322, 2330, 2818, 2802, 2815, 2813, 2814, 2295, 2870, 2835, 2838, 2384, 2849, 2847, 2395, 2377, 2880, 2354, 2879, 2923, 2369, 2930, 2934, 2922, 2916, 2451, 2455, 2954, 2960, 2409, 2410, 2944, 2941, 2940, 2431, 2424, 2985, 2964, 2968, 2504, 2970, 2973, 2969, 3001, 2462, 3024, 3020, 3019, 2475, 3036, 2541, 2518, 3047, 3071, 2526, 3067], "full": [1806, 2964, 1743, 2462, 1461, 2409, 3047, 1601, 1745, 2802, 1242, 1170, 2410, 1890, 260, 1675, 2835, 2032, 2968, 2969, 2518, 1963, 239, 2838, 2766, 1248, 732, 3201, 2295, 3135, 3157, 2354, 1321, 2682, 2769, 1322, 3102, 1324, 2879, 2970, 2581, 3067, 2880, 2232, 2424, 2526, 1473, 2916, 3163, 2687, 1977, 3169, 2588, 2644, 2690, 2847, 2940, 1264, 2239, 2813, 2849, 443, 2475, 290, 2814, 2176, 2533, 2776, 2941, 3076, 115, 3036, 2973, 2241, 2052, 2815, 1839, 3077, 2369, 1626, 3089, 2242, 2944, 2732, 2653, 2922, 3149, 2431, 2818, 3139, 1989, 1414, 3150, 2779, 1126, 2595, 3071, 2923, 2655, 2186, 2541, 3019, 3140, 250, 153, 2782, 3001, 3160, 3142, 2377, 3020, 1703, 413, 2252, 2742, 2602, 2194, 3151, 2322, 1496, 1284, 2384, 1710, 3128, 2325, 2664, 1856, 1285, 2666, 1929, 1858, 3166, 2329, 1788, 1931, 958, 2330, 2007, 2746, 3024, 960, 1015, 1504, 1505, 1651, 2930, 1290, 2504, 1795, 2791, 2084, 2985, 2750, 2954, 140, 2451, 2672, 1658, 1576, 966, 2087, 1580, 569, 2395, 1228, 2960, 2455, 1732, 1025, 2023, 2214, 1668, 3084, 2934, 2759, 3185, 1381, 2870, 527]}}, "Mrna splicing": {"direction": "dw", "overlap": {"value": 86, "mean": 48.28883495145631, "std": 18.528162023337615, "bin": {}}, "setsize": {"value": 138, "mean": 142.3228155339806, "std": 7.100537640996984, "bin": {}}, "score": {"value": -6.40302818895511, "mean": -0.6040586609434766, "std": 1.2901632086040689, "bin": {}}, "pval": {"value": 1.5232505530428188e-10, "mean": 0.555878613477235, "std": 0.3655002719916655, "bin": {}}, "signature_idxs": {"edge": [3084, 3076, 2602, 3089, 3102, 2595, 2581, 3128, 2588, 3142, 3140, 3135, 2653, 3151, 3150, 3149, 3157, 3160, 3163, 3169, 2644, 3185, 3201, 2682, 2690, 2759, 2732, 2782, 2252, 2232, 2779, 2766, 2242, 2241, 2776, 2239, 2325, 2330, 2818, 2802, 2815, 2813, 2814, 2295, 2870, 2835, 2838, 2384, 2849, 2395, 2377, 2880, 2354, 2879, 2923, 2369, 2930, 2934, 2922, 2916, 2451, 2455, 2409, 2410, 2944, 2941, 2431, 2424, 2985, 2964, 2968, 2504, 2970, 2973, 2969, 3001, 2462, 3024, 3020, 3019, 3036, 2541, 3047, 3071, 2526, 3067], "full": [2964, 1743, 2462, 1461, 2409, 3047, 1601, 1745, 2802, 1242, 1170, 2410, 1890, 260, 2835, 2032, 2968, 2969, 1963, 239, 2838, 2766, 1248, 3201, 2295, 3135, 3157, 2354, 1321, 2682, 1322, 3102, 1324, 2879, 2970, 2581, 3067, 2880, 2232, 2424, 2526, 1473, 2916, 3163, 3169, 2588, 2644, 2690, 1264, 2239, 2813, 2849, 443, 2814, 2176, 2776, 2941, 3076, 115, 3036, 2973, 2241, 2052, 2815, 2369, 1626, 3089, 2242, 2944, 2732, 2653, 2922, 3149, 2431, 2818, 1989, 1414, 3150, 2779, 1126, 2595, 3071, 2923, 2541, 3019, 3140, 250, 153, 2782, 3001, 3160, 3142, 2377, 3020, 1703, 2252, 2602, 2194, 3151, 1496, 2384, 1710, 3128, 2325, 1856, 1285, 1788, 958, 2330, 2007, 3024, 960, 1015, 1504, 2930, 2504, 2084, 2985, 140, 2451, 1658, 1576, 966, 2087, 569, 2395, 1228, 2455, 1732, 1025, 2214, 1668, 3084, 2934, 2759, 3185, 2870, 527]}}, "Metabolism of rna": {"direction": "dw", "overlap": {"value": 141, "mean": 151.2597087378641, "std": 47.911457858114936, "bin": {}}, "setsize": {"value": 478, "mean": 457.9538834951457, "std": 22.758873431475507, "bin": {}}, "score": {"value": -5.102198824133186, "mean": -1.0055551942090837, "std": 1.2609348121138049, "bin": {}}, "pval": {"value": 3.357297646111225e-07, "mean": 0.4350500122971218, "std": 0.3457084215001203, "bin": {}}, "signature_idxs": {"edge": [2538, 2537, 3084, 2535, 2533, 2532, 3082, 3077, 3076, 2602, 3089, 2612, 3092, 2596, 3102, 2595, 3122, 3119, 2579, 3113, 2581, 2584, 2589, 2593, 3130, 3128, 2590, 2588, 3139, 3142, 3140, 2655, 2654, 2653, 3135, 3151, 2676, 2664, 2666, 3150, 3149, 2672, 3146, 3157, 3160, 3166, 3163, 3169, 2644, 2641, 3185, 2713, 2706, 2719, 3201, 2718, 2696, 3214, 2687, 2679, 2682, 2690, 2750, 2745, 2748, 2746, 2751, 2759, 2742, 2732, 2727, 2731, 2736, 2782, 2791, 2794, 2779, 2760, 2766, 2769, 2776, 2775, 2821, 2834, 2818, 2802, 2815, 2812, 2813, 2814, 2856, 2870, 2835, 2838, 2849, 2846, 2847, 2893, 2894, 2903, 2885, 2872, 2880, 2883, 2879, 2923, 2930, 2934, 2922, 2904, 2908, 2916, 2954, 2957, 2958, 2960, 2944, 2941, 2940, 2981, 2985, 2964, 2968, 2970, 2973, 2969, 3001, 3028, 3032, 3024, 3020, 3019, 3044, 3043, 3036, 3035, 3062, 3050, 3047, 3071, 3067], "full": [1886, 1806, 847, 1091, 393, 2872, 2157, 1671, 2904, 3146, 2760, 530, 1887, 1888, 2964, 576, 1961, 1743, 2462, 727, 1461, 1672, 2409, 3047, 1601, 1745, 1169, 2802, 579, 1242, 2679, 1170, 196, 2410, 1890, 260, 2908, 1675, 1676, 2835, 2032, 2968, 2969, 92, 3113, 2518, 535, 623, 1963, 239, 2838, 2766, 2415, 1248, 1965, 8, 3050, 399, 732, 2166, 3201, 2295, 625, 1967, 3135, 3157, 2354, 1321, 2682, 2579, 2769, 1322, 3102, 1256, 789, 1324, 2879, 1325, 147, 2727, 2168, 1258, 3214, 2970, 2581, 1819, 790, 2584, 3067, 792, 2470, 2880, 991, 1260, 22, 440, 265, 690, 2232, 793, 2424, 1043, 1471, 1530, 360, 582, 2169, 1395, 2526, 1473, 1330, 2170, 2916, 2641, 3163, 2687, 406, 2174, 1977, 3169, 2588, 2589, 1826, 2112, 2590, 2644, 2690, 13, 1617, 2812, 1536, 922, 866, 1692, 1192, 1047, 2846, 2427, 923, 2236, 246, 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{"bin_50": 1, "bin_100": 1, "bin_250": 3, "bin_500": 11}}, "setsize": {"value": 45, "mean": 43.58252427184466, "std": 2.4879291964009105, "bin": {"bin_50": 68, "bin_100": 68, "bin_250": 68, "bin_500": 68}}, "score": {"value": 3.339681612862461, "mean": 0.43538002101356, "std": 1.318650463428372, "bin": {"bin_50": 4.431079894644425, "bin_100": 1.7846481876332625, "bin_250": 1.9687002652519892, "bin_500": 3.93049078392183}}, "pval": {"value": 0.0008387448886277, "mean": 0.532490131621357, "std": 0.3690692407606546, "bin": {"bin_50": 0.2091124120315671, "bin_100": 0.435125531031766, "bin_250": 0.2065117323393839, "bin_500": 0.0003292538654226}}, "signature_idxs": {"edge": [246, 876, 144, 623, 265, 22, 268, 636, 151, 406, 973, 393, 790, 603, 685, 440, 446, 582, 898, 880, 847, 652, 360], "full": [847, 1091, 393, 1671, 1887, 1031, 1672, 623, 685, 1325, 790, 1260, 22, 440, 265, 1471, 1530, 360, 582, 406, 1617, 923, 246, 268, 1117, 636, 1480, 1765, 1909, 1986, 1547, 876, 446, 151, 1273, 1628, 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{"value": 0.00085014252254, "mean": 0.5132999135100862, "std": 0.3668156388656303, "bin": {"bin_50": 0.1698682334931245, "bin_100": 0.3644392114350391, "bin_250": 0.0354529720255955, "bin_500": 6.461532350619225e-06}}, "signature_idxs": {"edge": [246, 876, 144, 623, 265, 22, 268, 636, 151, 406, 973, 393, 790, 471, 781, 603, 440, 211, 582, 898, 847, 652, 360], "full": [847, 1091, 393, 1671, 1887, 1672, 781, 211, 623, 1325, 790, 1260, 22, 440, 265, 1471, 1530, 360, 582, 406, 1617, 923, 246, 268, 1117, 636, 1480, 1909, 1986, 1547, 876, 151, 1273, 2821, 1350, 652, 898, 603, 471, 144, 973]}}, "Acyl chain remodelling of ps": {"direction": "dw", "overlap": {"value": 1, "mean": 0.6599496221662469, "std": 0.6003634478400364, "bin": {}}, "setsize": {"value": 1, "mean": 1.3727959697732997, "std": 0.4835484822580718, "bin": {}}, "score": {"value": -3.330506944807225, "mean": -0.1904732999744472, "std": 1.778072970684161, "bin": {}}, "pval": {"value": 0.0008668800114741, "mean": 0.3190142198116437, "std": 0.3114329884235925, "bin": {}}, "signature_idxs": {"edge": [2793], "full": [2793]}}, "Synthesis of dolichyl phosphate": {"direction": "up", "overlap": {"value": 0, "mean": 0.525, "std": 0.6186342484322488, "bin": {"bin_50": 0, "bin_100": 0, "bin_250": 0, "bin_500": 1}}, "setsize": {"value": 1, "mean": 1.6694444444444445, "std": 0.6865046105066692, "bin": {"bin_50": 5, "bin_100": 5, "bin_250": 5, "bin_500": 5}}, "score": {"value": 3.32965211516172, "mean": 0.5233899375810995, "std": 1.746200203954798, "bin": {"bin_50": 0.0, "bin_100": 0.0, "bin_250": 0.0, "bin_500": 5.013946280991736}}, "pval": {"value": 0.0008695455239042, "mean": 0.3479783848098225, "std": 0.339940279844701, "bin": {"bin_50": 1.0, "bin_100": 1.0, "bin_250": 1.0, "bin_500": 0.2163008837372877}}, "signature_idxs": {"edge": [], "full": [457]}}, "Vitamin b2 riboflavin metabolism": {"direction": "up", "overlap": {"value": 0, "mean": 0.5153061224489796, "std": 0.5974182619893988, "bin": {"bin_50": 0, "bin_100": 0, "bin_250": 0, "bin_500": 1}}, "setsize": {"value": 1, "mean": 1.3596938775510203, "std": 0.5809105345457157, "bin": {"bin_50": 4, "bin_100": 4, "bin_250": 4, "bin_500": 4}}, "score": {"value": 3.3281651446764973, "mean": 0.4020995995076505, "std": 1.6081351373582091, "bin": {"bin_50": 0.0, "bin_100": 0.0, "bin_250": 0.0, "bin_500": 6.68595041322314}}, "pval": {"value": 0.0008742002791972, "mean": 0.3318117529704842, "std": 0.3172891342391689, "bin": {"bin_50": 1.0, "bin_100": 1.0, "bin_250": 1.0, "bin_500": 0.177144185336352}}, "signature_idxs": {"edge": [], "full": [458]}}, "Regulation of pten stability and activity": {"direction": "up", "overlap": {"value": 23, "mean": 12.611650485436892, "std": 7.056269001912706, "bin": {"bin_50": 1, "bin_100": 1, "bin_250": 3, "bin_500": 11}}, "setsize": {"value": 42, "mean": 41.82281553398058, "std": 2.1755846965350556, "bin": {"bin_50": 63, "bin_100": 63, "bin_250": 63, "bin_500": 63}}, "score": {"value": 3.3238453954368743, "mean": 0.6486618107800725, "std": 1.2659780846667748, "bin": {"bin_50": 4.790796963946869, "bin_100": 1.929531490015361, "bin_250": 2.1338362068965515, "bin_500": 4.310654008438819}}, "pval": {"value": 0.0008878540205496, "mean": 0.5229501310802542, "std": 0.3745012259374719, "bin": {"bin_50": 0.1953081045789589, "bin_100": 0.4108204639824847, "bin_250": 0.1771731074813362, "bin_500": 0.0001639127097563}}, "signature_idxs": {"edge": [246, 876, 144, 623, 265, 554, 22, 268, 636, 151, 406, 973, 393, 790, 603, 440, 582, 898, 524, 847, 652, 242, 360], "full": [847, 1091, 393, 1671, 1887, 1672, 623, 1254, 1325, 242, 790, 1260, 22, 440, 265, 1471, 1530, 360, 582, 406, 1617, 923, 246, 268, 1117, 636, 1480, 1909, 1986, 1547, 876, 554, 151, 1273, 2821, 1350, 652, 898, 603, 144, 524, 973]}}, "G2 phase": {"direction": "up", "overlap": {"value": 0, "mean": 0.5313351498637602, "std": 0.6028760447030124, "bin": {"bin_50": 0, "bin_100": 0, "bin_250": 0, "bin_500": 1}}, "setsize": {"value": 1, "mean": 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3.528361344537815, "bin_100": 1.4210600907029478, "bin_250": 2.112126556571001, "bin_500": 4.767219801613053}}, "pval": {"value": 0.0009507534625339, "mean": 0.5709255515574044, "std": 0.3860301174542495, "bin": {"bin_50": 0.2543476608260538, "bin_100": 0.5105834798541556, "bin_250": 0.1326204837623513, "bin_500": 2.01776670101289e-06}}, "signature_idxs": {"edge": [246, 876, 144, 623, 265, 22, 268, 636, 151, 406, 640, 973, 393, 790, 547, 471, 781, 475, 603, 440, 439, 449, 446, 211, 582, 898, 880, 847, 652, 360], "full": [847, 1091, 393, 1671, 1887, 1672, 781, 211, 623, 1325, 790, 439, 1470, 1260, 22, 440, 265, 1471, 1530, 360, 582, 2110, 1187, 1823, 1613, 406, 1617, 923, 246, 268, 547, 1117, 636, 1480, 1909, 1986, 1547, 876, 640, 446, 151, 2433, 1273, 449, 880, 1349, 2821, 1350, 652, 3074, 898, 603, 2716, 471, 1882, 1589, 1731, 475, 1590, 144, 973]}}, "C type lectin receptors clrs": {"direction": "up", "overlap": {"value": 27, "mean": 15.640776699029129, "std": 8.889127611188893, 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"full": [2692]}}, "Sumoylation of rna binding proteins": {"direction": "dw", "overlap": {"value": 17, "mean": 11.080097087378642, "std": 5.683897540659047, "bin": {}}, "setsize": {"value": 32, "mean": 31.83252427184466, "std": 2.2627439388728945, "bin": {}}, "score": {"value": -3.2476593317902225, "mean": -0.1919874870556263, "std": 0.9298229348189392, "bin": {}}, "pval": {"value": 0.0011635849533693, "mean": 0.649712190416739, "std": 0.3254358140988572, "bin": {}}, "signature_idxs": {"edge": [3201, 2750, 2533, 2769, 2746, 2776, 2664, 2940, 2666, 2687, 2475, 2791, 2518, 2847, 2742, 2954, 3139], "full": [2518, 3201, 2769, 2687, 1977, 2847, 2940, 2475, 290, 2533, 2776, 1839, 3139, 2742, 2322, 1711, 2664, 2666, 1929, 1858, 2329, 1931, 2746, 1505, 1795, 2791, 2750, 2954, 1944, 1580, 2023, 2027]}}, "Signaling by tgf beta receptor complex in cancer": {"direction": "up", "overlap": {"value": 0, "mean": 0.3025477707006369, "std": 0.4928080264186791, "bin": {"bin_50": 0, "bin_100": 0, 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{"value": 2, "mean": 2.366504854368932, "std": 0.5478505372284339, "bin": {"bin_50": 7, "bin_100": 7, "bin_250": 7, "bin_500": 7}}, "score": {"value": 3.2248731942192137, "mean": -0.530710826054965, "std": 1.085348282983829, "bin": {"bin_50": 0.0, "bin_100": 20.04960317460317, "bin_250": 7.09045584045584, "bin_500": 8.038095238095238}}, "pval": {"value": 0.0012602847736959, "mean": 0.5087576029149842, "std": 0.3240824847404142, "bin": {"bin_50": 1.0, "bin_100": 0.0569331866004399, "bin_250": 0.1506421963771433, "bin_500": 0.0404448203812275}}, "signature_idxs": {"edge": [83], "full": [259, 83]}}, "Tnfr1 mediated ceramide production": {"direction": "up", "overlap": {"value": 0, "mean": 0.720873786407767, "std": 0.4485696941144109, "bin": {"bin_50": 0, "bin_100": 0, "bin_250": 0, "bin_500": 0}}, "setsize": {"value": 1, "mean": 1.0, "std": 0.0, "bin": {"bin_50": 3, "bin_100": 3, "bin_250": 3, "bin_500": 3}}, "score": {"value": 3.2158597099264377, "mean": -1.0208892096662905, "std": 1.827171007388144, "bin": {"bin_50": 0.0, "bin_100": 0.0, "bin_250": 0.0, "bin_500": 0.0}}, "pval": {"value": 0.0013005439240156, "mean": 0.2297852023292357, "std": 0.2821514571367339, "bin": {"bin_50": 1.0, "bin_100": 1.0, "bin_250": 1.0, "bin_500": 1.0}}, "signature_idxs": {"edge": [], "full": [553]}}, "Viral messenger rna synthesis": {"direction": "dw", "overlap": {"value": 19, "mean": 11.220873786407768, "std": 6.355736741539839, "bin": {}}, "setsize": {"value": 35, "mean": 34.41747572815534, "std": 2.2908609982905, "bin": {}}, "score": {"value": -3.2117726148082366, "mean": -0.2632815055090717, "std": 0.7751584621286535, "bin": {}}, "pval": {"value": 0.0013191874272637, "mean": 0.7082888325200691, "std": 0.3017066758535532, "bin": {}}, "signature_idxs": {"edge": [2533, 2940, 2687, 2750, 2746, 2970, 2581, 2847, 2742, 3139, 2954, 2664, 2666, 2475, 2791, 2880, 2769, 2518, 2526], "full": [1743, 2518, 2769, 1322, 2970, 2581, 2880, 2526, 2687, 1977, 2847, 2940, 2475, 290, 2533, 2241, 2052, 1839, 3139, 2742, 2322, 2664, 2666, 1929, 1858, 2329, 1931, 2746, 1505, 1795, 2791, 2750, 2954, 1580, 2023]}}, "Atf6 atf6 alpha activates chaperone genes": {"direction": "dw", "overlap": {"value": 2, "mean": 1.3422330097087378, "std": 0.5968061141941203, "bin": {}}, "setsize": {"value": 2, "mean": 2.016990291262136, "std": 0.1292347525434382, "bin": {}}, "score": {"value": -3.207192437013223, "mean": -0.5825450739467622, "std": 1.0487140609744774, "bin": {}}, "pval": {"value": 0.0013403730087382, "mean": 0.548532229981257, "std": 0.3265898780558095, "bin": {}}, "signature_idxs": {"edge": [3052, 2913], "full": [3052, 2913]}}, "Scavenging by class a receptors": {"direction": "dw", "overlap": {"value": 2, "mean": 1.25, "std": 0.9100970822000948, "bin": {}}, "setsize": {"value": 2, "mean": 2.9514563106796117, "std": 0.6134201552983035, "bin": {}}, "score": {"value": -3.207192437013223, "mean": -0.3034202338319282, "std": 1.081829275337707, "bin": {}}, "pval": {"value": 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"bin": {}}, "pval": {"value": 0.0013750797675706, "mean": 0.0465602836219474, "std": 0.1224919585458108, "bin": {}}, "signature_idxs": {"edge": [2710], "full": [2710]}}, "Formation of apoptosome": {"direction": "up", "overlap": {"value": 1, "mean": 1.0097087378640777, "std": 1.0634724733504557, "bin": {"bin_50": 0, "bin_100": 0, "bin_250": 1, "bin_500": 2}}, "setsize": {"value": 2, "mean": 3.228155339805826, "std": 0.9354836219504358, "bin": {"bin_50": 11, "bin_100": 11, "bin_250": 11, "bin_500": 11}}, "score": {"value": 3.194286025134366, "mean": 0.2480528982202133, "std": 1.0523011680504897, "bin": {"bin_50": 0.0, "bin_100": 0.0, "bin_250": 4.252564102564103, "bin_500": 4.463768115942029}}, "pval": {"value": 0.0014017715765557, "mean": 0.5379221970101167, "std": 0.3235131485152152, "bin": {"bin_50": 1.0, "bin_100": 1.0, "bin_250": 0.226342145869144, "bin_500": 0.0934868087275193}}, "signature_idxs": {"edge": [145], "full": [145, 288]}}, "Signaling by mapk mutants": {"direction": 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