Add training library: frozen homology-cold splits, audits, evaluation artifacts, and v10 release archive

.gitattributes

@@ -1 +1,3 @@
 * text=auto
+data/homology_split.parquet filter=lfs diff=lfs merge=lfs -text
+release/software-implementation-v10-redacted.zip filter=lfs diff=lfs merge=lfs -text

README.md

@@ -0,0 +1,170 @@
+---
+license: other
+license_name: mixed-mit-cc0-cc-by-4.0
+task_categories:
+- other
+tags:
+- biology
+- chemistry
+- enzymes
+- enzyme-kinetics
+- kcat
+- homology-split
+- mmseqs2
+- protein-language-model
+- enzyme-engineering
+size_category: 10K<n<100K
+pretty_name: BioCandidateRanker Training Library (frozen splits, audits, and release archive)
+---
+
+# BioCandidateRanker Training Library
+
+**中文说明见下方 [中文说明](#中文说明) 一节。**
+
+This repository is the organized, license-compliant training library of the
+[BioCandidateRanker](https://github.com/liubuing/BioCandidateRanker) project — a host-aware multimodal enzyme
+candidate scoring research system whose first trained task predicts `log10(kcat)` from
+protein sequence, substrate molecular graph, organism/EC/reaction context, and optional
+FBA features.
+
+It packages everything needed to **reproduce the exact training setup**: the frozen
+homology-cold split assignments, ingestion audit manifests, source identity hashes,
+external evaluation selections, and the official software release archive.
+
+> **What is deliberately NOT here:** the UniKP/DLKcat measurement rows themselves
+> (protein sequences + substrates + `kcat` values). The upstream compilation has no
+> redistribution grant on record (`license: unknown`, record-level provenance
+> corpus-level only), so the project's fail-closed license governance
+> (`configs/data_license_inventory.json` in the archive) marks it
+> `redistribution: not_verified` and blocks any measurement row from shipping in a
+> public archive. See [Reconstructing the full training corpus](#reconstructing-the-full-training-corpus)
+> to rebuild the corpus from the original public source and verify it bit-for-bit.
+
+## Contents
+
+```
+data/
+  homology_split.parquet          16,838 rows: source_row, sequence_id, cluster, split
+  homology_split.json             original frozen split manifest (redacted paths)
+  unikp_audit.json                ingestion audit of the development corpus (row counts,
+                                  duplicates, conflicts, source SHA256; redacted path)
+  unikp-km-training-blocker-audit.json      why governed Km training is blocked
+  absolute-activity-training-blocker-audit.json
+  full-homology-baseline/test_metrics.json  frozen baseline holdout metrics
+  enzengdb-v1/                    EnzEngDB v1 selection, homology-cold audits,
+                                  rank split, zero-shot transfer result, 3-seed summary
+  lunzer-imdh/                    Lunzer IMDH selection, homology audit, frozen
+                                  BioCandidateRanker and DLKcat evaluations
+  temporal/                       temporal absolute-kinetics pool readiness audits,
+                                  accepted-component FASTA and exact row mapping
+  uncertainty-calibration-v2/grouped-cv.json
+configs/
+  unikp_source_manifest.json      source identity and adapter statistics
+  data_license_inventory.json     the full license governance file governing this repo
+  temporal_absolute_kinetics_protocol.json
+release/
+  software-implementation-v10-redacted.zip        official release archive (408 files)
+  software-implementation-v10-redacted-manifest.json   per-file SHA256 manifest
+RECONSTRUCTION.md                 step-by-step corpus reconstruction guide
+```
+
+## The frozen homology-cold split
+
+The development corpus is split **protein-homology-cold** with MMseqs2 `linclust`
+(30% min identity, 80% coverage, coverage mode 0, seed 42), producing 2,204 clusters.
+Whole clusters are assigned to a partition, so no protein family leaks between
+train and evaluation:
+
+| split | rows |
+|---|---|
+| train | 13,470 |
+| validation | 1,684 |
+| test | 1,684 |
+
+The split is keyed by `source_row` (the 0-based row index in the original
+`Kcat_combination_0918_wildtype_mutant.json`), so it can be applied to any
+byte-identical copy of the source file:
+
+```python
+from datasets import load_dataset
+import json
+
+split = load_dataset("<repo-id>", data_files="data/homology_split.parquet")["train"]
+# row: {"source_row": 0, "sequence_id": "seq_...", "cluster": "seq_...", "split": "train"}
+```
+
+**Note:** the split manifest contains cluster/row/split assignments only — no
+sequences and no `kcat` values — which is exactly why it is redistributable while
+the corpus itself is not.
+
+## Reconstructing the full training corpus
+
+1. Obtain `Kcat_combination_0918_wildtype_mutant.json` from the original
+   [UniKP repository](https://github.com/Luo-SynBioLab/UniKP) (the file is also the
+   wildtype+mutant kcat compilation distributed with
+   [DLKcat](https://zenodo.org/records/6438262)).
+2. Verify the frozen source identity:
+
+   | field | value |
+   |---|---|
+   | SHA256 | `13643b0b36374f8d3f64d8b014882cf1b3b58946eeaae2b9dcd59e8b2c2d6719` |
+   | size | 12,132,719 bytes |
+   | rows | 17,010 |
+
+   The audit on this machine confirmed a byte-identical copy (2026-10-24).
+3. Run the project's audit and training CLI (included in `release/*.zip`) as
+   described in `RECONSTRUCTION.md`.
+
+Full step-by-step instructions: **[RECONSTRUCTION.md](RECONSTRUCTION.md)**.
+
+## External evaluation data included
+
+| component | source | license | shipped content |
+|---|---|---|---|
+| EnzEngDB v1 | Zenodo DOI `10.5281/zenodo.17310823` | CC-BY-4.0 | selection manifests, homology-cold audit, rank split, evaluation results (the 30 MB source archive is **not** bundled — fetch it from the DOI) |
+| Lunzer IMDH landscape | Dryad DOI `10.5061/dryad.7nd70` | CC0-1.0 | project-generated selection, homology audit, and frozen evaluations (source `.xls` not bundled) |
+| Temporal absolute-kinetics pool | 18+ CC0 / CC-BY-4.0 deposits | CC0 / CC-BY-4.0 per source | readiness audits, accepted-component FASTA, row mapping (curation pool below its gates — never scored, **not** a benchmark) |
+
+## Release archive
+
+`release/software-implementation-v10-redacted.zip` is the official deterministic
+release archive (`software-implementation-v10`): every Git-tracked source file plus
+38 frozen evidence artifacts, built by `scripts/build_release_archive.py` with
+license-ownership verification and absolute-path redaction. Its embedded and sidecar
+manifests carry per-file SHA256 hashes; the archive SHA256 is
+`34e42f5b211bd590b785abe3ff59ac2cfaaca801328ddef68c9b303044b394d8`.
+
+The archive includes the trained baseline checkpoint
+(`artifacts/full-homology-baseline/best.pt`), which the license inventory explicitly
+permits as a derived artifact (weights are not a redistribution of measurements).
+
+## License and attribution
+
+- **This package's own content** (splits, audits, configs, code in the archive):
+  MIT, © 2026 BioCandidateRanker authors.
+- **EnzEngDB v1**: CC-BY-4.0 — cite the Zenodo deposit DOI `10.5281/zenodo.17310823`.
+- **Lunzer IMDH landscape**: CC0-1.0 — Dryad DOI `10.5061/dryad.7nd70`.
+- **UniKP/DLKcat corpus**: **not redistributed here.** If you reconstruct it, respect
+  the upstream terms and cite the UniKP and DLKcat papers.
+
+## Citation
+
+If you use this split or the reconstruction protocol, please cite the upstream
+sources and this dataset:
+
+```bibtex
+@software{biocandidateranker2026,
+  title  = {BioCandidateRanker training library: frozen homology-cold splits and audits},
+  author = {BioCandidateRanker authors},
+  year   = {2026},
+  note   = {software-implementation-v10 release archive}
+}
+```
+
+## 中文说明
+
+本仓库是 BioCandidateRanker 项目的**训练库合规整理包**,目标是让任何人都能精确重建训练设置:
+
+- **包含**:冻结的 MMseqs2 同源冷划分(2,204 个簇,16,838 行 → train 13,470 / validation 1,684 / test 1,684,按原始文件行号索引)、摄入审计 manifest、源文件 SHA256 身份、EnzEngDB(CC-BY-4.0)与 Lunzer IMDH(CC0)的外部评估选择与结果、时间池就绪审计、以及官方 `software-implementation-v10` 全量发布档案(含基线模型权重 `best.pt`)。
+- **不包含**:UniKP/DLKcat 训练语料的测量行本体(序列、底物、kcat 值)。项目许可治理文件 `configs/data_license_inventory.json` 将其标记为 `not_verified` 并明确禁止任何测量行进入公开档案——上游(BRENDA 编译)无逐条记录的再分发授权。请通过 `RECONSTRUCTION.md` 从原始公开来源获取并按 SHA256 校验。
+- 训练语料原始出处:[UniKP (Luo-SynBioLab)](https://github.com/Luo-SynBioLab/UniKP)、[UniKP 论文 (Yu et al., Nat Commun)](https://pmc.ncbi.nlm.nih.gov/articles/PMC10713628)、[DLKcat 补充数据 (Zenodo)](https://zenodo.org/records/6438262)。

RECONSTRUCTION.md

@@ -0,0 +1,115 @@
+# Reconstructing the BioCandidateRanker training corpus
+
+This guide rebuilds the exact development corpus, frozen split, and baseline
+evaluation from the public upstream source plus the artifacts in this repository.
+It never requires the measurement rows to pass through this dataset repository.
+
+## 1. Obtain the original corpus
+
+Download `Kcat_combination_0918_wildtype_mutant.json` from the original
+[UniKP repository](https://github.com/Luo-SynBioLab/UniKP). The same wildtype+mutant
+kcat compilation was distributed with DLKcat
+([Zenodo record 6438262](https://zenodo.org/records/6438262)).
+
+## 2. Verify the frozen identity
+
+The project's frozen manifests pin the source bytes. Compute:
+
+```bash
+sha256sum Kcat_combination_0918_wildtype_mutant.json
+```
+
+Expected:
+
+```
+13643b0b36374f8d3f64d8b014882cf1b3b58946eeaae2b9dcd59e8b2c2d6719  (12,132,719 bytes, 17,010 rows)
+```
+
+If the hash differs, stop: the split assignments in `data/homology_split.parquet`
+are keyed by row index and are only valid for a byte-identical copy. Cross-check
+against `configs/unikp_source_manifest.json` and `data/unikp_audit.json` in this
+repository. A verified copy was confirmed on 2026-10-24.
+
+## 3. Audit the corpus with the project CLI
+
+Unpack `release/software-implementation-v10-redacted.zip`, then:
+
+```powershell
+python -m venv .venv
+.\.venv\Scripts\python.exe -m pip install -e ".[dev]"
+$env:PYTHONPATH="src"
+python -m biocandidate.cli audit-data `
+  --data "<path>\Kcat_combination_0918_wildtype_mutant.json" `
+  --output artifacts\unikp_audit.json
+```
+
+Expected adapter statistics (recorded in `configs/unikp_source_manifest.json`):
+
+| field | value |
+|---|---|
+| total rows | 17,010 |
+| accepted | 16,838 |
+| duplicates | 395 |
+| conflicting duplicates | 215 |
+| rejected | 172 |
+
+## 4. Apply the frozen homology-cold split
+
+The split in `data/homology_split.parquet` / `data/homology_split.json` maps each
+0-based `source_row` to an MMseqs2 cluster and a partition (MMseqs2 `linclust`,
+min identity 0.3, coverage 0.8, coverage mode 0, seed 42; 2,204 clusters;
+13,470 / 1,684 / 1,684 rows). Join it to the source file by row index:
+
+```python
+import json
+import pandas as pd
+
+source = json.load(open("Kcat_combination_0918_wildtype_mutant.json", encoding="utf-8"))
+split = pd.read_parquet("data/homology_split.parquet").set_index("source_row")
+train = [source[i] for i in split.index[split["split"] == "train"]]
+```
+
+Or let the CLI bind the identity itself (recommended — it refuses a source that
+does not match the audit manifest):
+
+```powershell
+python -m biocandidate.cli train `
+  --data "<path>\Kcat_combination_0918_wildtype_mutant.json" `
+  --manifest artifacts\unikp_audit.json `
+  --split-manifest artifacts\homology-final\homology_split.json `
+  --output-dir artifacts\training
+```
+
+(`artifacts/homology-final/homology_split.json` is included byte-identical inside
+the release archive; the copy under `data/` here is the same file with its one
+embedded local path redacted.)
+
+## 5. Reproduce the frozen baseline evaluation
+
+The baseline checkpoint `artifacts/full-homology-baseline/best.pt` ships inside
+the release archive. Evaluate the test partition:
+
+```powershell
+python -m biocandidate.cli evaluate `
+  --checkpoint artifacts\full-homology-baseline\best.pt `
+  --data "<path>\Kcat_combination_0918_wildtype_mutant.json" `
+  --manifest artifacts\unikp_audit.json `
+  --split-manifest artifacts\homology-final\homology_split.json `
+  --partition test `
+  --output artifacts\full-homology-baseline\test_metrics.json
+```
+
+Reference result: `data/full-homology-baseline/test_metrics.json`.
+
+> torch >= 2.6 note: `predict`/`evaluate` checkpoint loading with
+> `weights_only=True` rejects pre-2.6 checkpoints. Install `torch<2.6` for CLI
+> reproduction, or use the workbench server path documented in the README.
+
+## 6. License obligations
+
+- The corpus rows stay out of public archives: upstream terms are unresolved
+  (`configs/data_license_inventory.json`, corpus `unikp-kcat-development-corpus`).
+- If you redistribute anything derived from the corpus, resolve the upstream terms
+  first and cite the UniKP and DLKcat papers.
+- EnzEngDB v1 (CC-BY-4.0) and the Lunzer IMDH landscape (CC0) have their own
+  attribution requirements documented in the dataset card.

configs/data_license_inventory.json

@@ -0,0 +1,227 @@
+{
+  "schema_version": 1,
+  "updated_on": "2026-09-24",
+  "purpose": "Declare every corpus the project reads, its license basis, whether this project may redistribute it, and where that claim is evidenced. scripts/audit_development_corpus_license.py verifies this file and scripts/build_release_archive.py consults release_paths before shipping.",
+  "policy": {
+    "license_is_not_redistribution_right": "A permissive license on code does not grant redistribution rights over data compiled from third-party databases.",
+    "blocked_until_evidenced": "A corpus marked not_verified must not ship measurement data inside a public release archive.",
+    "evidence_required": "Every entry must name at least one repository path that a reader can open to check the claim.",
+    "release_paths_are_authoritative": "release_paths maps frozen artifact paths to the corpus they belong to; an unowned path is an audit failure.",
+    "allowed_redistribution_states": [
+      "permitted_with_attribution",
+      "permitted_unconditionally",
+      "not_verified",
+      "blocked_pending_permission",
+      "not_applicable_reference_only"
+    ]
+  },
+  "corpora": [
+    {
+      "id": "unikp-kcat-development-corpus",
+      "role": "development_training",
+      "description": "UniKP/DLKcat kcat development corpus used for all trained models and the frozen homology-cold split.",
+      "identity": {
+        "sha256": "13643b0b36374f8d3f64d8b014882cf1b3b58946eeaae2b9dcd59e8b2c2d6719",
+        "size_bytes": 12132719,
+        "rows": 17010,
+        "record_level_citations_available": false
+      },
+      "license_name": "unknown",
+      "license_basis": "Corpus-level provenance only. Underlying measurements derive primarily from BRENDA as compiled by the UniKP project; no record-level citation or redistribution grant is recorded.",
+      "redistribution": "not_verified",
+      "redistribute_in_release": false,
+      "blocking_reason": "Upstream compilation terms are unresolved, so no measurement row from this corpus may ship in a public archive.",
+      "release_paths": [],
+      "measurement_data_shipped": false,
+      "derived_artifacts_in_release": [
+        {
+          "path": "artifacts/unikp_audit.json",
+          "kind": "ingestion audit metadata",
+          "contains_measurements": false,
+          "note": "Row counts, duplicate counts, and the source file hash only. Carries a local absolute source path that must be redacted before a double-blind deposit.",
+          "redaction_required": ["source"]
+        },
+        {
+          "path": "artifacts/unikp-km-training-blocker-audit.json",
+          "kind": "blocker audit metadata",
+          "contains_measurements": false,
+          "note": "Records why governed Km training is blocked; no Km values or sequences."
+        },
+        {
+          "path": "artifacts/homology-final/homology_split.json",
+          "kind": "record identifier mapping",
+          "contains_measurements": false,
+          "note": "Holds cluster id, sequence id, source row, and split assignment only; no sequences and no kcat values."
+        },
+        {
+          "path": "artifacts/full-homology-baseline/best.pt",
+          "kind": "trained model weights",
+          "contains_measurements": false,
+          "note": "Derived from the corpus. Weights are not a redistribution of the measurements, but the derivation is declared so reviewers can judge fit."
+        }
+      ],
+      "evidence": [
+        "configs/unikp_source_manifest.json",
+        "configs/temporal_absolute_kinetics_protocol.json",
+        "docs/PCB_BASELINE_AND_ENDPOINT_AUDIT_CN.md"
+      ],
+      "blocks": [
+        "public release of the training corpus",
+        "manuscript data availability statement asserting open training data"
+      ]
+    },
+    {
+      "id": "enzengdb-v1",
+      "role": "external_evaluation",
+      "description": "EnzEngDB v1 engineering-fitness campaigns used for zero-shot ranking evaluation.",
+      "identity": {
+        "doi": "10.5281/zenodo.17310823",
+        "archive_bytes": 30050527,
+        "archive_sha256": "8013ad81586db2187162aada0709c1cabc7e7d69f03dd5c199776aaf000dd6ea"
+      },
+      "license_name": "CC-BY-4.0",
+      "license_basis": "Deposit record declares CC BY 4.0.",
+      "redistribution": "permitted_with_attribution",
+      "redistribute_in_release": false,
+      "release_paths": [],
+      "note": "Selection and audit artifacts ship; the 30 MB source archive does not, to keep the deposit lean.",
+      "evidence": [
+        "artifacts/external/enzengdb-v1/audit.json",
+        "artifacts/external/enzengdb-v1/selection-homology-cold.json"
+      ]
+    },
+    {
+      "id": "lunzer-imdh-landscape",
+      "role": "external_evaluation",
+      "description": "Lunzer ancient adaptive IMDH six-site landscape used for mutation-sensitivity testing.",
+      "identity": {
+        "doi": "10.5061/dryad.7nd70",
+        "genotypes": 512
+      },
+      "license_name": "CC0-1.0",
+      "license_basis": "Dryad deposit declares CC0.",
+      "redistribution": "permitted_unconditionally",
+      "redistribute_in_release": false,
+      "release_paths": [],
+      "note": "Source landscape is not bundled; only project-generated evaluation outputs would ship.",
+      "evidence": [
+        "docs/RESEARCH_PROTOCOL.md",
+        "docs/CURRENT_RESULTS.md"
+      ]
+    },
+    {
+      "id": "temporal-absolute-kinetics-pool",
+      "role": "prospective_independent_benchmark",
+      "description": "Frozen temporal and homology-cold absolute-kinetics pool. Below its record and family gates, never scored.",
+      "identity": {
+        "accepted_sources": 18,
+        "records_after_family_cap": 192,
+        "global_families": 25,
+        "unique_substrates": 54
+      },
+      "license_name": "CC0-1.0 or CC-BY-4.0 per source",
+      "license_basis": "The frozen protocol admits only CC0 or CC BY 4.0 measurement tables with explicit deposit coverage. Per-source coverage is asserted by the acquisition registry.",
+      "redistribution": "permitted_with_attribution",
+      "redistribute_in_release": true,
+      "release_paths": [
+        "artifacts/external/temporal-absolute-kinetics/",
+        "artifacts/external/temporal-global-family-audit/"
+      ],
+      "scientific_caveat": "Pool is below its record and family gates and has never been scored. Its presence in the archive is frozen input evidence, not a released benchmark, and must not be cited as validation.",
+      "evidence": [
+        "configs/temporal_absolute_kinetics_protocol.json",
+        "artifacts/external/temporal-global-family-audit/readiness-audit.json",
+        "artifacts/external/temporal-absolute-kinetics/candidate_registry.json"
+      ]
+    },
+    {
+      "id": "project-generated-outputs",
+      "role": "project_generated",
+      "description": "Artifacts this project generated itself: smoke splits, calibration cross-validation, and blocker audits.",
+      "license_name": "project-generated, released with the code",
+      "license_basis": "Produced by this repository; no third-party measurement content.",
+      "redistribution": "permitted_unconditionally",
+      "redistribute_in_release": true,
+      "release_paths": [
+        "artifacts/simulated-flux-smoke/",
+        "artifacts/uncertainty-calibration-v2/",
+        "artifacts/absolute-activity-training-blocker-audit.json"
+      ],
+      "evidence": [
+        "configs/software_implementation_release_v6.json"
+      ]
+    },
+    {
+      "id": "catapro-upstream",
+      "role": "modern_comparator",
+      "description": "CataPro source, pinned weights, and published kcat table used for the fixed-split internal comparison.",
+      "identity": {
+        "overlap_with_project_test": "1127/1646 exact sequence and canonical-SMILES pairs"
+      },
+      "license_name": "MIT (code)",
+      "license_basis": "MIT covers the code repository. It does not by itself settle redistribution of the published kcat table or of independently licensed base-model weights.",
+      "redistribution": "blocked_pending_permission",
+      "redistribute_in_release": false,
+      "blocking_reason": "Data and base-model weight terms are separate from the code license and remain unresolved.",
+      "release_paths": [
+        "artifacts/catapro-mode-b/"
+      ],
+      "evidence": [
+        "docs/PCB_BASELINE_AND_ENDPOINT_AUDIT_CN.md",
+        "docs/CATAPRO_INTERNAL_COMPARISON_CN.md",
+        "configs/catapro_internal_test_freeze.json"
+      ]
+    },
+    {
+      "id": "catpred-upstream",
+      "role": "modern_comparator",
+      "description": "CatPred source and weights used for the Mode B reproducibility attempt.",
+      "license_name": "MIT (code)",
+      "license_basis": "MIT covers the code repository; training-data and weight terms are separate.",
+      "redistribution": "blocked_pending_permission",
+      "redistribute_in_release": false,
+      "blocking_reason": "Data and weight terms unresolved; the protocol iteration is also incomplete.",
+      "release_paths": [
+        "artifacts/catpred-mode-b/"
+      ],
+      "evidence": [
+        "docs/CATPRED_MODE_B_RUNBOOK_CN.md",
+        "docs/CATPRED_RECOVERY_CN.md",
+        "configs/catpred_mode_b_protocol_v3.json"
+      ]
+    },
+    {
+      "id": "dlkcat-upstream",
+      "role": "legacy_comparator",
+      "description": "DLKcat source used as the GPL-3.0-only comparison on the IMDH landscape and as a retrained Mode B baseline.",
+      "license_name": "GPL-3.0-only (code)",
+      "license_basis": "Code is legally runnable under GPL-3.0-only. Record-level training-source overlap with the project test remains unresolved.",
+      "redistribution": "not_applicable_reference_only",
+      "redistribute_in_release": false,
+      "blocking_reason": "Reference-only comparator: the project ships no DLKcat code, weights, or derived data.",
+      "release_paths": [],
+      "evidence": [
+        "docs/SOTA_BASELINE_COMPARISON_PLAN.md",
+        "docs/CURRENT_RESULTS.md"
+      ]
+    },
+    {
+      "id": "sabio-rk-km",
+      "role": "governed_km_candidate",
+      "description": "SABIO-RK Km rows considered for governed Km training. Permission request drafted but not sent.",
+      "license_name": "not established",
+      "license_basis": "Row-level metadata exists, but assay chains and permission for training and artifact use are unresolved.",
+      "redistribution": "blocked_pending_permission",
+      "redistribute_in_release": false,
+      "blocking_reason": "No permission grant on file; the request has not been sent.",
+      "release_paths": [
+        "artifacts/external/governed-km-sabio-rk/"
+      ],
+      "evidence": [
+        "docs/external-requests/SABIO_RK_PERMISSION_REQUEST.md",
+        "artifacts/external/governed-km-sabio-rk/blocker.json",
+        "configs/external_data_blockers.json"
+      ]
+    }
+  ]
+}

configs/temporal_absolute_kinetics_protocol.json

@@ -0,0 +1,85 @@
+{
+  "protocol_version": 1,
+  "frozen_on": "2026-07-20",
+  "purpose": "Prospective temporal and homology-cold absolute enzyme kinetics benchmark",
+  "development_corpus": {
+    "name": "UniKP/DLKcat kcat development corpus",
+    "sha256": "13643b0b36374f8d3f64d8b014882cf1b3b58946eeaae2b9dcd59e8b2c2d6719",
+    "size_bytes": 12132719,
+    "rows": 17010,
+    "record_level_citations_available": false
+  },
+  "temporal_gate": {
+    "primary_measurement_article_published_on_or_after": "2023-01-01",
+    "deposit_date_alone_is_not_sufficient": true,
+    "preprints_require_a_stable_doi_and_explicit_dataset_license": true
+  },
+  "license_gate": {
+    "accepted": [
+      "CC0-1.0",
+      "CC-BY-4.0"
+    ],
+    "deposit_license_must_cover_the_measurement_table": true,
+    "third_party_database_compilations_require_source_level_redistribution_rights": true
+  },
+  "record_inclusion": {
+    "direct_experimental_measurement": true,
+    "accepted_endpoints": [
+      "kcat_s-1",
+      "km_molar",
+      "kcat_per_km_M-1_s-1"
+    ],
+    "primary_endpoint": "log10_kcat_s-1",
+    "full_protein_sequence_or_unambiguous_accession_and_variant": true,
+    "single_defined_substrate_with_structure_identifier": true,
+    "required_provenance": [
+      "measurement_article_doi",
+      "dataset_doi_or_stable_record_url",
+      "source_file",
+      "source_row_or_table_cell",
+      "organism",
+      "enzyme_identity",
+      "substrate_name",
+      "endpoint",
+      "value",
+      "unit",
+      "assay_temperature_if_reported",
+      "assay_pH_if_reported"
+    ],
+    "derived_kcat_requires_enzyme_concentration_and_documented_formula": true,
+    "model_predictions_pseudolabels_and_relative_activity_are_excluded": true,
+    "bulk_environmental_or_community_apparent_kinetics_are_excluded": true
+  },
+  "leakage_gates": {
+    "exact_sequence_substrate_overlap_with_development": 0,
+    "mmseqs_min_identity": 0.3,
+    "mmseqs_coverage": 0.8,
+    "mmseqs_coverage_mode": 0,
+    "exclude_all_sequences_with_development_hit": true,
+    "publication_overlap": "exclude_when_known; report unavailable when development citations are absent",
+    "substrate_exact_and_murcko_scaffold_overlap": "report_and_stratify"
+  },
+  "diversity_and_size_gate": {
+    "minimum_records": 300,
+    "minimum_mmseqs_families": 30,
+    "minimum_unique_substrates": 50,
+    "maximum_records_per_family": 20,
+    "minimum_records_per_reported_family_metric": 3
+  },
+  "freeze_policy": {
+    "candidate_metadata_and_homology_may_be_audited_before_freeze": true,
+    "model_predictions_are_prohibited_before_final_selection_freeze": true,
+    "labels_may_not_drive_record_caps_or_family_selection": true,
+    "primary_model_checkpoint_and_metrics_must_be_frozen_before_evaluation": true,
+    "one_final_evaluation_only": true,
+    "failed_readiness_gate_means_no_model_evaluation": true
+  },
+  "planned_comparators": [
+    "train_mean",
+    "morgan_mlp",
+    "late_concat",
+    "task_query",
+    "DLKcat_when_training_overlap_is_reported_as_unavailable"
+  ],
+  "claim_boundary": "Until every readiness gate passes, collected records are a curation pool and not an external benchmark. No model may be selected or tuned from this pool."
+}

configs/unikp_source_manifest.json

@@ -0,0 +1,18 @@
+{
+  "adapter": {
+    "accepted_rows": 16838,
+    "conflicting_duplicate_rows": 215,
+    "duplicate_rows": 395,
+    "rejected_rows": 172,
+    "total_rows": 17010
+  },
+  "identity": {
+    "row_count": 17010,
+    "sha256": "13643b0b36374f8d3f64d8b014882cf1b3b58946eeaae2b9dcd59e8b2c2d6719",
+    "size_bytes": 12132719
+  },
+  "license_status": "redistribution_not_verified",
+  "source_dataset": "UniKP/DLKcat kcat development corpus",
+  "source_path_is_external_and_read_only": true,
+  "upstream_record_provenance": "corpus_level_only"
+}

data/absolute-activity-training-blocker-audit.json

@@ -0,0 +1,265 @@
+{
+  "schema_version": "1.0.0",
+  "audit_date": "2026-07-27",
+  "task": "BioCandidateRanker governed absolute activity training from repository-local sources",
+  "target_model_field": "log10_activity",
+  "status": "blocked",
+  "decision": {
+    "training_performed": false,
+    "adapter_written": false,
+    "canonical_unit_defined": false,
+    "normalized_dataset_written": false,
+    "family_split_written": false,
+    "cpu_smoke_performed": false,
+    "checkpoint_written": false,
+    "predictions_used_as_labels": false,
+    "fitness_used_as_labels": false,
+    "reason_code": "INSUFFICIENT_COMPATIBLE_DIRECT_ABSOLUTE_ACTIVITY_ROWS_AND_FAMILIES",
+    "summary": "No repository-local source provides enough compatible, governed, direct absolute activity measurements for family-aware log10_activity training. Turnover constants remain kcat labels; EnzEngDB fitness remains campaign-relative; Lunzer values have an unresolved absolute unit; RFU/min is instrument-relative; and the only shared physical activity dimension, mass-specific rate, has at most 23 rows in three families before scientific gates and at most 10 coherent rows in one family after the locally documented assay and consistency gates.",
+    "claim_boundary": "This is a source and compatibility audit only. No labels were created, no endpoint was relabeled, no split or model was produced, and no model scoring was run."
+  },
+  "search_scope": {
+    "root": "<redacted-local-path>",
+    "repository_is_git_worktree": false,
+    "included": [
+      "source adapters and curation scripts under src/ and scripts/",
+      "repository-local tabular, JSON, archive, workbook, sequence, audit, metric, checkpoint, and prediction artifacts",
+      "all source directories under artifacts/external/absolute-kinetics-screen",
+      "all source directories under artifacts/external/temporal-absolute-kinetics",
+      "all EnzEngDB v1 campaign files and audits under artifacts/external/enzengdb-v1",
+      "existing UniKP manifests and audits under artifacts/ and configs/"
+    ],
+    "endpoint_terms": [
+      "activity",
+      "specific activity",
+      "Vmax",
+      "U mg^-1",
+      "umol min^-1 mg^-1",
+      "RFU/min",
+      "fitness_value",
+      "kcat",
+      "rate"
+    ],
+    "exclusion_policy": [
+      "Do not rename kcat, Km, kcat/Km, fitness, relative activity, inhibition, simulated flux, or predictions as activity.",
+      "Require a finite direct experimental value, an explicit physical unit and denominator, exact sequence and defined substrate inputs, row-level provenance, and permission-compatible local evidence.",
+      "Require assay semantics to be compatible before pooling values that happen to share dimensions.",
+      "Require complete protein families to stay within one train, validation, or test partition."
+    ]
+  },
+  "candidate_canonical_dimension": {
+    "dimension": "amount of product per time per mass of protein",
+    "interconvertible_source_units": [
+      "U mg^-1",
+      "umol min^-1 mg^-1"
+    ],
+    "possible_canonical_unit_if_unblocked": "log10(umol min^-1 mg^-1)",
+    "defined_for_training": false,
+    "reason_not_defined": "Dimensional convertibility is not sufficient. After directness, assay-validity, conversion-consistency, provenance, and family gates, the local pool collapses to one family with at most 10 rows. Declaring a model-wide canonical activity unit would falsely imply an adequate governed training endpoint."
+  },
+  "source_buckets": [
+    {
+      "source_id": "temporal-global-family-audit",
+      "path": "artifacts/external/temporal-global-family-audit/readiness-audit.json",
+      "endpoint": "direct steady-state kcat",
+      "unit": "s^-1 after source-specific normalization",
+      "records": 177,
+      "families": 21,
+      "substrates": 50,
+      "activity_eligible_records": 0,
+      "reason": "A molar turnover constant is a governed log10_kcat endpoint, not a mass-specific or condition-specific activity endpoint. Relabeling is prohibited."
+    },
+    {
+      "source_id": "UniKP-kcat-development",
+      "path": "artifacts/unikp_audit.json",
+      "endpoint": "kcat",
+      "total_rows": 17010,
+      "adapter_accepted_rows": 16838,
+      "activity_eligible_records": 0,
+      "reason": "The source and implemented task are log10_kcat. It also lacks row-level accessions and a bundled independent split; no kcat value was relabeled as activity."
+    },
+    {
+      "source_id": "EnzEngDB-v1",
+      "path": "artifacts/external/enzengdb-v1/audit.json",
+      "endpoint": "fitness_value",
+      "total_rows": 462092,
+      "adapter_accepted_rows": 245945,
+      "campaigns": 160,
+      "activity_eligible_records": 0,
+      "reason": "Fitness has campaign-specific meaning and units. The existing adapter intentionally leaves log10_activity unset and permits only within-campaign ranking. EnzEngDB was excluded from the activity candidate count."
+    },
+    {
+      "source_id": "Lunzer-Dryad-7nd70",
+      "path": "artifacts/external/absolute-kinetics-screen/dryad-4964723/Lunzer Curated Biochemistry.xls",
+      "source_identity": {
+        "sha256": "7bfd71d78235ade06a9e117b8229ad99b1fe7adceb0a5ed72d708c3e925c2a69",
+        "size_bytes": 38761
+      },
+      "endpoint": "derived ln(Km) + ln(kcat/Km)",
+      "records": 1024,
+      "families": 1,
+      "activity_eligible_records": 0,
+      "reason": "The absolute source-unit constant is unresolved and all 512 sequences have development-corpus homology hits. Existing use is ranking within cofactor only."
+    },
+    {
+      "source_id": "mLDHD-S-EPMC10589216",
+      "path": "artifacts/external/temporal-absolute-kinetics/biostudies-S-EPMC10589216/exclusions.csv",
+      "endpoint": "Michaelis-Menten Vmax reported as mass-specific activity",
+      "unit": "umol min^-1 mg^-1",
+      "candidate_rows": 9,
+      "families": 1,
+      "direct_dimensionally_compatible_rows": 9,
+      "scientifically_eligible_rows": 0,
+      "reason": "Every row uses a PMS-DCIP coupled assay without demonstrated saturation of either fixed electron acceptor. The local provenance audit excludes all nine apparent rates; none may become an activity label merely because Vmax has a compatible unit."
+    },
+    {
+      "source_id": "Pantoea-GDH-S-EPMC12364357",
+      "path": "artifacts/external/temporal-absolute-kinetics/biostudies-S-EPMC12364357",
+      "endpoint": "Michaelis-Menten Vmax reported as mass-specific activity",
+      "unit": "U mg^-1",
+      "candidate_rows": 10,
+      "families": 1,
+      "direct_dimensionally_compatible_rows": 10,
+      "rows_passing_local_cosubstrate_saturation_rule": 1,
+      "rows_with_development_homology": 10,
+      "training_eligible_rows": 0,
+      "reason": "Only one row passes the local >=5x fixed-cosubstrate Km rule, and the complete family is excluded by development homology. The ten values are useful provenance evidence but cannot support a family-aware activity split."
+    },
+    {
+      "source_id": "SlDefH-PMC13230308",
+      "path": "artifacts/external/temporal-absolute-kinetics/europepmc-PMC13230308/blocker-evidence.json",
+      "endpoint": "specific activity or Vmax",
+      "unit": "U mg^-1",
+      "candidate_rows": 4,
+      "families": 1,
+      "direct_dimensionally_compatible_rows": 4,
+      "training_eligible_rows": 0,
+      "reason": "The completed source audit found zero independently reconcilable rows. Each reported specific-activity/kcat pair implies approximately 599 kDa versus the stated 29.5 kDa sequence mass, while the article and complete supplement provide no kinetic enzyme molarity, conversion equation, oligomer measurement, active-site stoichiometry, or active-enzyme fraction. Reported values remain provenance evidence only; the local registry finalizes this source at zero rows."
+    },
+    {
+      "source_id": "Zenodo-4448337",
+      "path": "artifacts/external/absolute-kinetics-screen/zenodo-4448337/source.zip",
+      "source_identity": {
+        "sha256": "8ef6d1a23ba3d5a614c5670fabc28daf8644a4d1d1320f0a0850a54f1088090a",
+        "size_bytes": 4637
+      },
+      "endpoint": "kcat, Km, kcat/Km, and cofactor preference",
+      "activity_eligible_records": 0,
+      "reason": "The archive contains turnover kinetics and a dimensionless preference series, not a governed absolute activity endpoint."
+    },
+    {
+      "source_id": "Zenodo-20626217-Dataset-S1",
+      "path": "artifacts/external/absolute-kinetics-screen/zenodo-20626217/Dataset_S1.xlsx",
+      "source_identity": {
+        "sha256": "83f559a75277c87c307fadb93393b6090a628055fc4c4e8a96d8e0e6e48d5338",
+        "size_bytes": 84504
+      },
+      "endpoint": "BACE1 inhibition and instrument response rates",
+      "units": [
+        "percent inhibition",
+        "IC50 in uM",
+        "Ki in uM",
+        "RFU/min"
+      ],
+      "activity_eligible_records": 0,
+      "reason": "RFU/min lacks a physical amount calibration and protein-mass denominator; inhibition endpoints describe peptides acting on BACE1 rather than enzyme-candidate catalytic activity."
+    },
+    {
+      "source_id": "model-and-simulation-artifacts",
+      "paths": [
+        "artifacts/candidate_predictions.json",
+        "artifacts/external/absolute-kinetics-screen/dryad-4964723/dlkcat-output.tsv",
+        "artifacts/external/absolute-kinetics-screen/dryad-4964723/biocandidate-full-evaluation.json",
+        "artifacts/external/enzengdb-v1/zero-shot-kcat-proxy.json",
+        "artifacts/simulated-flux-smoke"
+      ],
+      "activity_eligible_records": 0,
+      "reason": "Predictions, model metrics, checkpoints, and simulated flux are not direct experimental activity labels."
+    }
+  ],
+  "mass_specific_activity_funnel": {
+    "dimensionally_compatible_candidate_rows": 23,
+    "candidate_sources": 3,
+    "candidate_families": 3,
+    "excluded_coupled_assay_rows": 9,
+    "excluded_internal_conversion_inconsistency_rows": 4,
+    "coherent_direct_rows_before_homology_and_saturation_gates": 10,
+    "coherent_direct_families_before_homology_and_saturation_gates": 1,
+    "rows_passing_existing_saturation_and_homology_gates": 0,
+    "families_passing_existing_saturation_and_homology_gates": 0,
+    "maximum_rows_if_homology_exclusion_were_ignored": 1,
+    "maximum_families_if_homology_exclusion_were_ignored": 1
+  },
+  "family_split_audit": {
+    "required_partitions": [
+      "train",
+      "validation",
+      "test"
+    ],
+    "assignment_unit": "complete protein homology family",
+    "label_independent_assignment_required": true,
+    "candidate_families_before_scientific_gates": 3,
+    "eligible_families_after_scientific_gates": 0,
+    "split_feasible": false,
+    "reason": "Even the permissive dimensional pool would place only one family in each partition with no within-partition family diversity. After existing scientific gates there are no eligible families, so a leakage-aware split cannot be written."
+  },
+  "incompatibility_counts": {
+    "heterogeneous_fitness_rows_explicitly_excluded": 245945,
+    "governed_kcat_rows_not_relabelled": 177,
+    "unikp_kcat_adapter_rows_not_relabelled": 16838,
+    "unit_ambiguous_lunzer_rows_not_relabelled": 1024,
+    "mass_specific_candidate_rows": 23,
+    "mass_specific_candidate_families": 3,
+    "mass_specific_rows_rejected_by_assay_or_consistency": 13,
+    "mass_specific_rows_rejected_by_existing_saturation_or_homology_gates": 10,
+    "eligible_activity_rows": 0,
+    "eligible_activity_families": 0
+  },
+  "blocking_findings": [
+    {
+      "code": "ENDPOINT_SEMANTICS_INCOMPATIBLE",
+      "severity": "fatal",
+      "detail": "kcat, kcat/Km, fitness, inhibition, instrument response, relative activity, and simulated flux are distinct endpoints and cannot be pooled as log10_activity."
+    },
+    {
+      "code": "MASS_SPECIFIC_POOL_TOO_SMALL",
+      "severity": "fatal",
+      "detail": "Only 23 dimensionally compatible candidate rows in three families exist before scientific gates; at most 10 coherent rows remain in one family before homology and saturation gates."
+    },
+    {
+      "code": "NO_ELIGIBLE_FAMILY_SPLIT",
+      "severity": "fatal",
+      "detail": "No family remains eligible after the locally documented assay-validity, conversion-consistency, saturation, and development-homology gates."
+    },
+    {
+      "code": "CANONICAL_UNIT_PREMATURE",
+      "severity": "fatal",
+      "detail": "Defining log10(umol min^-1 mg^-1) as a training endpoint would imply unsupported comparability across apparent Vmax, coupled assays, fixed-condition specific activity, and inconsistent conversions."
+    }
+  ],
+  "conditions_to_unblock": [
+    "Acquire direct purified-enzyme activity rows with a single prespecified physical denominator and auditable conversion to it; do not substitute kcat or fitness.",
+    "Preserve per-row source file/cell, DOI or stable record, exact construct sequence, defined substrate structure, assay conditions, replicate/error semantics, evidence tier, and license provenance.",
+    "Prespecify whether the endpoint is saturating mass-specific Vmax or activity at a fixed substrate protocol; do not pool those assay semantics without a validated normalization model.",
+    "Resolve coupled-assay saturation and SlDefH conversion inconsistencies before admission.",
+    "Acquire enough independent homology families to populate train, validation, and test with meaningful family diversity, then freeze a label-independent family assignment.",
+    "Only after those gates pass, define the canonical unit, implement a strict activity-specific adapter, and run a CPU training smoke."
+  ],
+  "evidence_files": [
+    "README.md",
+    "src/biocandidate/data/normalized_kinetics.py",
+    "src/biocandidate/data/enzengdb.py",
+    "src/biocandidate/data/lunzer.py",
+    "configs/temporal_absolute_kinetics_protocol.json",
+    "artifacts/unikp_audit.json",
+    "artifacts/external/enzengdb-v1/audit.json",
+    "artifacts/external/absolute-kinetics-screen/dryad-4964723/selection.json",
+    "artifacts/external/absolute-kinetics-screen/dryad-4964723/homology-audit.json",
+    "artifacts/external/temporal-absolute-kinetics/registry-readiness-audit.json",
+    "artifacts/external/temporal-global-family-audit/readiness-audit.json",
+    "artifacts/external/temporal-absolute-kinetics/biostudies-S-EPMC10589216/provenance.json",
+    "artifacts/external/temporal-absolute-kinetics/biostudies-S-EPMC12364357/provenance.json",
+    "artifacts/external/temporal-absolute-kinetics/candidate_registry.json",
+    "artifacts/external/temporal-absolute-kinetics/third_round_discovery_registry.json"
+  ]
+}

data/enzengdb-v1/audit-homology-cold.json

@@ -0,0 +1,113 @@
+{
+  "adapter": {
+    "accepted_campaigns": 160,
+    "accepted_rows": 245945,
+    "rejected_rows": 216147,
+    "rejection_reasons": {
+      "aa_sequence contains non-canonical residues: #": 99,
+      "aa_sequence contains non-canonical residues: #.": 123,
+      "aa_sequence contains non-canonical residues: *": 45890,
+      "fitness_value is missing or non-numeric": 3447,
+      "reaction SMILES must contain exactly one >> separator": 20,
+      "reaction has no concrete carbon-containing reactant": 166568
+    },
+    "source_files": 179,
+    "total_rows": 462092
+  },
+  "dataset": "EnzEngDB v1",
+  "dataset_doi": "10.5281/zenodo.17310823",
+  "exact_unikp_overlap": {
+    "sequence": 0,
+    "sequence_substrate_pair": 0,
+    "substrate": 297,
+    "unikp_publication_overlap": "unavailable_no_record_level_citations"
+  },
+  "frozen_selection": {
+    "campaign_counts": {
+      "DHFR": 2000,
+      "ParLQ-a": 492,
+      "ParLQ-b": 94,
+      "ParLQ-c": 94,
+      "ParLQ-d": 94,
+      "ParLQ-e": 94,
+      "ParLQ-f": 94,
+      "ParLQ-g": 94,
+      "ParLQ-h": 94,
+      "ParLQ-i": 94,
+      "Rma-CB": 162,
+      "Rma-CSi": 162,
+      "exp_0": 32,
+      "exp_1": 96,
+      "exp_11": 46,
+      "exp_13": 31,
+      "exp_17": 26,
+      "exp_19": 35,
+      "exp_20": 41,
+      "exp_201": 313,
+      "exp_202": 316,
+      "exp_25": 50,
+      "exp_26": 20,
+      "exp_3": 20,
+      "exp_31": 180,
+      "exp_33": 38,
+      "exp_34": 21,
+      "exp_35": 84,
+      "exp_36": 397,
+      "exp_37": 397,
+      "exp_6": 31,
+      "exp_8": 34,
+      "exp_LLM101": 29,
+      "exp_LLM12": 28,
+      "exp_LLM15": 40,
+      "exp_LLM16": 24,
+      "exp_LLM21": 30,
+      "exp_LLM23": 29,
+      "exp_LLM26": 30,
+      "exp_LLM27": 33,
+      "exp_LLM39": 29,
+      "exp_LLM43": 21,
+      "exp_LLM44": 30,
+      "exp_LLM55": 34,
+      "exp_LLM6": 57,
+      "exp_LLM62": 62,
+      "exp_LLM84": 21,
+      "exp_LLM87": 56,
+      "exp_LLM9": 53,
+      "exp_LLM93": 21,
+      "exp_LLM97": 20
+    },
+    "campaigns": 51,
+    "manifest": "<redacted-local-path>",
+    "records": 6423
+  },
+  "homology_unikp_overlap": {
+    "coverage": 0.8,
+    "coverage_mode": 0,
+    "hits_identity": {
+      "row_count": 20426,
+      "sha256": "388d060ad3293e6ad64de9a81a1960b37ddd12757678bf23b0528378b10d4fa6",
+      "size_bytes": 1838499
+    },
+    "hits_path": "<redacted-local-path>",
+    "method": "MMseqs2 easy-search",
+    "min_identity": 0.3,
+    "retained_homology_cold_campaigns": 51,
+    "retained_homology_cold_records": 6423,
+    "selected_records_with_hit": 22823,
+    "unique_external_sequences": 24205,
+    "unique_sequences_with_hit": 20426
+  },
+  "license": "CC-BY-4.0",
+  "limitations": [
+    "fitness_value has campaign-specific units and is valid only for within-campaign ranking.",
+    "Largest concrete carbon-containing reactant is selected deterministically.",
+    "Publication overlap cannot be audited because UniKP lacks row-level citations.",
+    "MMseqs2 hits were removed from the frozen selection."
+  ],
+  "source_archive": "<redacted-local-path>",
+  "source_archive_identity": {
+    "row_count": 462092,
+    "sha256": "8013ad81586db2187162aada0709c1cabc7e7d69f03dd5c199776aaf000dd6ea",
+    "size_bytes": 30050527
+  }
+}

data/enzengdb-v1/audit.json

@@ -0,0 +1,147 @@
+{
+  "adapter": {
+    "accepted_campaigns": 160,
+    "accepted_rows": 245945,
+    "rejected_rows": 216147,
+    "rejection_reasons": {
+      "aa_sequence contains non-canonical residues: #": 99,
+      "aa_sequence contains non-canonical residues: #.": 123,
+      "aa_sequence contains non-canonical residues: *": 45890,
+      "fitness_value is missing or non-numeric": 3447,
+      "reaction SMILES must contain exactly one >> separator": 20,
+      "reaction has no concrete carbon-containing reactant": 166568
+    },
+    "source_files": 179,
+    "total_rows": 462092
+  },
+  "dataset": "EnzEngDB v1",
+  "dataset_doi": "10.5281/zenodo.17310823",
+  "exact_unikp_overlap": {
+    "sequence": 2,
+    "sequence_substrate_pair": 0,
+    "substrate": 20333,
+    "unikp_publication_overlap": "unavailable_no_record_level_citations"
+  },
+  "frozen_selection": {
+    "campaign_counts": {
+      "DHFR": 2000,
+      "ParLQ-a": 492,
+      "ParLQ-b": 94,
+      "ParLQ-c": 94,
+      "ParLQ-d": 94,
+      "ParLQ-e": 94,
+      "ParLQ-f": 94,
+      "ParLQ-g": 94,
+      "ParLQ-h": 94,
+      "ParLQ-i": 94,
+      "PfTrpB_4-bromo": 241,
+      "PfTrpB_4-cyano": 241,
+      "PfTrpB_5-bromo": 241,
+      "PfTrpB_5-chloro": 241,
+      "PfTrpB_5-cyano": 241,
+      "PfTrpB_5-iodo": 241,
+      "PfTrpB_6-chloro": 241,
+      "PfTrpB_7-bromo": 68,
+      "PfTrpB_7-iodo": 241,
+      "PfTrpB_7-methyl": 241,
+      "Rma-CB": 162,
+      "Rma-CSi": 162,
+      "TrpB_3A": 2000,
+      "TrpB_3B": 2000,
+      "TrpB_3C": 2000,
+      "TrpB_3D": 2000,
+      "TrpB_3E": 2000,
+      "TrpB_3F": 2000,
+      "TrpB_3G": 2000,
+      "TrpB_3H": 2000,
+      "TrpB_3I": 2000,
+      "TrpB_B4": 2000,
+      "exp_0": 32,
+      "exp_1": 96,
+      "exp_11": 79,
+      "exp_12": 54,
+      "exp_13": 31,
+      "exp_15": 28,
+      "exp_16": 56,
+      "exp_17": 29,
+      "exp_19": 35,
+      "exp_20": 41,
+      "exp_201": 313,
+      "exp_202": 316,
+      "exp_25": 50,
+      "exp_26": 20,
+      "exp_27": 37,
+      "exp_28": 27,
+      "exp_29": 27,
+      "exp_3": 20,
+      "exp_30": 26,
+      "exp_31": 180,
+      "exp_33": 38,
+      "exp_34": 21,
+      "exp_35": 84,
+      "exp_36": 397,
+      "exp_37": 397,
+      "exp_4": 28,
+      "exp_6": 31,
+      "exp_8": 37,
+      "exp_9": 22,
+      "exp_LLM101": 29,
+      "exp_LLM12": 28,
+      "exp_LLM15": 40,
+      "exp_LLM16": 24,
+      "exp_LLM21": 30,
+      "exp_LLM23": 29,
+      "exp_LLM26": 30,
+      "exp_LLM27": 33,
+      "exp_LLM3": 53,
+      "exp_LLM39": 29,
+      "exp_LLM42": 21,
+      "exp_LLM43": 21,
+      "exp_LLM44": 30,
+      "exp_LLM47": 31,
+      "exp_LLM55": 34,
+      "exp_LLM6": 57,
+      "exp_LLM62": 62,
+      "exp_LLM83": 29,
+      "exp_LLM84": 21,
+      "exp_LLM87": 56,
+      "exp_LLM89": 22,
+      "exp_LLM9": 53,
+      "exp_LLM91": 29,
+      "exp_LLM93": 21,
+      "exp_LLM97": 20,
+      "exp_LLM98": 59
+    },
+    "campaigns": 87,
+    "manifest": "<redacted-local-path>",
+    "records": 29248
+  },
+  "homology_unikp_overlap": {
+    "coverage": 0.8,
+    "coverage_mode": 0,
+    "hits_identity": {
+      "row_count": 20426,
+      "sha256": "02f29427fc99c41b5e80f4c7d5f8dcc16a613cdb8b0c6e0a721438fbf451ed6a",
+      "size_bytes": 1838499
+    },
+    "hits_path": "<redacted-local-path>",
+    "method": "MMseqs2 easy-search",
+    "min_identity": 0.3,
+    "selected_records_with_hit": 22823,
+    "unique_external_sequences": 24205,
+    "unique_sequences_with_hit": 20426
+  },
+  "license": "CC-BY-4.0",
+  "limitations": [
+    "fitness_value has campaign-specific units and is valid only for within-campaign ranking.",
+    "Largest concrete carbon-containing reactant is selected deterministically.",
+    "Publication overlap cannot be audited because UniKP lacks row-level citations.",
+    "Homology hits are reported, not silently removed from this transfer benchmark."
+  ],
+  "source_archive": "<redacted-local-path>",
+  "source_archive_identity": {
+    "row_count": 462092,
+    "sha256": "8013ad81586db2187162aada0709c1cabc7e7d69f03dd5c199776aaf000dd6ea",
+    "size_bytes": 30050527
+  }
+}

data/enzengdb-v1/rank-split/campaign_representatives.fasta

@@ -0,0 +1,274 @@
+>seq_0128cb6f247fc8b5a1757767
+VLSEGEWQLVLHVWAKVEADVAGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKGGATALTALGGILKKKGHHEAEIKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_0132e19a653d30ad50bb0c6f
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLWAGEKCLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAVMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGVEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPIVPQFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKERLTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_0289c3fa8a75bc6d931afd06
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLFAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLSLKPKGFVVKAKSKKIPLGGIPSPSTLEHHHHHH
+>seq_02f1c523958cf820d9d508c8
+VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKVGVTALTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGY
+>seq_040f50f491b9e9274d929440
+VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKGGVTALTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGY
+>seq_05103f4e4c76aabbb52070f2
+MISLIAALAVDRVIGMENAMPWNLPAAAAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVT
+>seq_054abda09b68fc21611daeae
+MTDRLKGKVAIVTGGTLGIGLAIADKFVEEGAKVVITGRHADVGEKAAKSIGGTDVIRFVQHDASDEAGWTKLFDTTEEAFGPVTTVVNNAGIAVSKSVEDTTTEEWRKLLSVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDPTLGAYNASKGAVRIMSKSAALDCALKDYDVRVNTVHPGCIKTPLVDDLEGAEEMMSQRTKTPMGHIGEPNDIAWICVYLASDESKFATGAEFVVDGGYTAQHHHHHH
+>seq_078a683b8fe316d77df8d951
+MWFGEFGGQYVPETLVGPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTVKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKASGNV
+>seq_07cdb15503342d0915d23569
+NEQLAKQKGCMACHDLKAKKVGPAYADVAKKYAGRKDAVDYLAGKIKKGTSGVWGSVPGPERNVTDAEAKQLAQWILSIK
+>seq_09630f65f45e8dbf0281de3d
+MAVPGYDFGKVPDAPISDADFESLKKTVMWGEEDEKYRKMACEALKGQVEDILDLWDGLQGSNQHLIYYFGDKSGRPIPQYLEAIRKRFGLWIIDTLCKPLDRQWLNYMYEIGLRHHRTKKGKTDGVDTVEHIPLRYMIAFIAPIGLTFKPILEKSGHPPEAVERMWAAWVKLVALRVAIWSYPYAKTGEW
+>seq_0bd235aa1e1a12de12e792fc
+VLSEGEWQLVLHVWAKVEADVAGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKVGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_0cc052ae15d8639cb9a2aa06
+MTDLKASSLRALKLMDLSTLNGDYTDEKVIALCHQAKTPVGNTAAISIYPRSIPIARKTLKEQGTPEIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIESGELKDEALIRKASEISIKAGADFIKTSTGLVAVNATPESARIMMEVIRDMGVEKSVGFKVTGGARTAEDAQKYLAIADELFGADWADARHYRFGASGLLASLLKALGHGDGKSASSYLEHHHHHH
+>seq_0d9da8f1429d42bb372d9620
+MNTMLFSPYTIRGLTLKNRIVMSPMCMYSCDTKDGAVRTWHKIHYPARAVGQVGLIIVEATWVTPQGRISERDLGIWSDDHIAGLRELVGLVKEHGAAIGIALAHAGRKSQVPGEIIAPSAVPFDDSSPTPKEMTKADIEETVQAFQNGARRAKEAGFDVIEIHAAAGFLINEFLSPLSNRRQDEYGGSPENRYRFLGEVIDAVREVWDGPLFVAISASDYHPDGLTAKDYVPYAKRMKEQGVDLVIVSSGAIVPARMNVYPGYQVPFAELIRREADIPTGAVGLITSGWQAEEILQNGRADLVFLGAELLRNPYWPYAAARELGAKISAPVQYERGWRFSAWSHPQFEK
+>seq_1207c07be4dcbbf3400b7362
+MPRYLKGWVEDIVQLSLRRPRVHASRQRPIISLNERILEFNKRNITAIIAYYTRKSPLGLVVERDPIEYAKYMERYAVGLSIKTEEKYFNGSYEMLHNIASSVSIPVLMNDFVVKESQIDDAYNLGADTVLLIVGILTERELESLLEYARSYGMEPLILINDENDLDIALRIGARFIVIFSLDFETGEINKENQRKLISMIPSDVVKVALLDIGERNEIEELRKLGVNAFLISSSLMRNPEKIKELIEGSLEHHHHHH
+>seq_15acb6ff6c04c210118ad8d1
+GFKQDIATIRGDLRTYAQDIFLAFLNKYPDERRYFKNYVGKSDQELKSMAKFGDATEKAFNLMMEVADRATDCVPLASDANTLVQMKQHSSLTTGNFEKLFVALVEYMRASGQSFDSQSWDRFGKNLVSALSSAGMK
+>seq_1c8b667c0208e1d5e17160fa
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLTQALKFMRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISYVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLMAGHDPTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPVVPAFSLYAKEDTVLGGEYPLEKGDEVEVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGVGQRGSIGAQFALHEATLVLGMMLKHFDFEDHTNYELDIKETFVLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_1d453fb170a63fb4795dd386
+MESGFTSKDTYLSHFNPRDYLEKFYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLIDIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGNRVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLHAACPDLPTYCRALRNLGSLLKPGGFLVIMDMLKSSYYMIGEQKFSALPLGREAVEAAVKEAGYTIEWFEVISQSYSSTMANNEGLFSLVARKLSRPLLEHHHHHH
+>seq_2510a9cf7e381123f3eb6bac
+VLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGY
+>seq_274ae1c00f773c58528c6322
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACLIGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDCSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_27ab1af16f4014a9aeee7431
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAAAAAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_29619dcf34d9c6f1b6248e31
+MENSFKAALKAGRPQIGLWLGLSSSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGTQTLLVPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNRIPDYLQKANDQMCVLVQIETREAMKNLPQILDVEGVDGVFIGPADLSADMGYAGNPQHPEVQAAIEQAIVQIRESGKAPGILIANEQLAKRYLELGALFVAVGVDTTLLARAAEALAARFGAQATAVKPGVY
+>seq_2ad06bcfe987eecd5a69f20e
+GAEIPKEMLRAQTNKILLNVLKQGDNYVYGIIKQVKEASNGEMELNEATLYTIFDRLEQDGIISSYWGDESQGGRRKYYRLTEIGHENMRLAFESWSRVDKIIENLEANKKSEAIKSRGGSGGWSHPQFEK
+>seq_2af6cf53ba0c140c72a31def
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFAGDGLTTSWTFEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRAGDEVMNKLQRANPDDPAYDESKRQFQEDIKVMNDQVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLMAGHEATSGLLSFALYFLLKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLCLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRTKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKDWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQSVDSAADMPLAKMHGAFSTNVVASKELQQ
+>seq_2e06483ac3e527c39359be27
+MRTSKKEMILRTAIDYIGEYSLETLSYDSLAEATGLSKSGLIYHFPSRHALLLGMHELLADDWDKELRDITRDPEDPLERLRAVVVTLAENVSRPELLLLIDAPSHPDFLNAWRTVNHQWIPDTDDLENDAHKRAVYLVQLAADGLFVHDYIHDDVLSKSKRQAMLETILELIPSELAAWSHPQFEKYS
+>seq_3070f6dbe4eee602fb6203f6
+MAVPGYDFGKVPDAPISDADFESLKKTVMWGEEDEKYRKMACEALKGQVEDILDLWYGFQGSNQHLIYYFGDKSGRPIPQYLEAVRKRFGLWIIDTLCKPLDRQWLNYMYEIGLRHHRTKKGKTDGVDTVEHIPLRYMIAFIAPIGLTIKPILEKSGHPPEAVERMWAAWVKLVVLQVAIWSYPYAKTGEW
+>seq_31fc278f98fb907ea2cce7c0
+TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFACHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTHHHHHH
+>seq_32827649f0b48d16858251f6
+MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMMEGISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEEGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVAAYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVGLNGAIVGMTTFGESAPAELLFEEFGFTVDNVVAKAKELLHHHHHH
+>seq_3490e63e4835338054ac746a
+MHHHHHHPTLFDPIDFGPIHAKNRIVMSPLTRGRADKEAVPTPIMAEYYAQRASAGLIITEATGISREGLGWPFAPGIWSDAQVEAWKPIVAGVHAKGGKIVCQLWHMGRMVHSSVTGTQPVSSSATTAPGEVWTYEGKKPFEQARAIDAADISRILNDYENAARNAIRAGFDGVQIHAANGFLIDEFLRNGTNHRTDEYGGVPENRIRFLKEVTERVIAAIGADRTGVRLSPNGDTQGCIDSAPETVFVPAAKLLQDLGVAWLELREPGPNGTFGKTDQPKLSPQIRKVFLRPLVLNQDYTFEAAQTALAEGKADAIAFGRKFISNPDLPERFARGIALQPDDMKTWASQGPEGYTDYPSATSGPNGACTATCCATCCGCAACTTCTGGGCCGAACTGA
+>seq_3fb4b59ad582bbad9c4bc618
+MTPSDIPGYDYGRVEKSPITDLEFDLLKKTVMLGEKDVVYLKKACDVLKDQVDEILDLAGGWVASNEHLIYYFSNPDTGEPIKEYLERVRARFGAWILDTTCRDYNREWLDYQYEVGLRHHRPKRGVTDGVRTVPHIPLRYLIAFIYLNTATIKPFLAKKGGSPEDIEGMYNAWFKSVVLQVAIWSHPYTKENDW
+>seq_4065426b02ba4e8f76b34ffe
+MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKLDRFKHLKTEAEMKASEDLKKVGVTALTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFVSEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_411f76e65e4babac204e1016
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKSLSQALKFLRDFMGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRAQDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTTPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASLGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLQLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_475cac6cd0160c0e830675ce
+MGSTAPLRLPVIDLSMKNLKPGTTSWNSVRTQVREALEEYGCFEAVIDAVSPELQKAVCNKGHELLNLPLETKMLNGNKPEYDGFTSIPNLNEGMGVGRITDLEKVERFTNLMWPEGNKDFCETVYSYGKRMAEVDHILKMMVFESFGMEKHFDSFCESTNYLLHFMRYQQPGKDGRSPALSLHKDKSILTIVNQNDVKGLEFETKDGEWILPTADNHIVLLGDCFMAWSNGRLHSPLHRVTLVANQARLSTSSFSFPKDIIETPAELVDEEHPLLFNPFEITELLAYCFTKEGAKAVCDLKQYKAYTGA
+>seq_4938789dfb906569adcba74b
+METMLFSPYTIRGVTLKNRIVMSPMSMFSCDTEDGKVRNWHKIHYPTRAVGQVGLIILEATAVTAQGRISSRDLGIWSDEHVGGLRELVSLVKEHGAKIGIQLAHAGRKSEVDGEIIAPSSIPFSEKTRTPKEMTKADIEETIQAFQNGARRAKEAGFDIIEIHAAHGYLINEFLSPLSNKRQDEYGGSPENRYRFLGEVIDAVKEVWDGPLFVRISASDYHPEGLTVKDYVPYAKRMKKQGVDLIDVSSGAVVPANISVYPGYQVPFAETIRREAEIATGAVGLITSGWQAEEILRNGRADLVFLARELLRNPYWPYAAAKELGTTIPAPVQYERGWRFLEHHHHHH
+>seq_495d7aa91044c4967423c937
+MWFGEFGGQYVPETLIEPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKIYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVFHGMLSYFLQDEEGQIKPTHSIAPGLDYPGVGPEHAYLKKIQRAEYVTVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKVSGNVLEHHHHHH
+>seq_4bd61ec42e09b68e990fca32
+MAANSTRRPIIAFMSDLGTTDDSVAQCKGLMYSICPDVTVVDVCHSMTPWDVEEGARYIVDLPRFFPEGTVFATTTYPATGTTTRSVAVRIKQAAKGGARGQWAGSGAGFERAEGSYIYIAPNNGLLTTVLEEHGYLEAYEVTSPKVIPEQPEPTFYSREMVAIPSAHLAAGFPLSEVGRPLEDHEIVRFNRPAVEQDGEALVGVVSAIDHPFGNVWTNIHRTDLEKAGIGYGARLRLTLDGVLPFEAPLTPTFADAGEIGNIAIYLNSRGYLSIARNALSLAYPYHLKEGMSARVEAR
+>seq_515743f58dcee53388b402aa
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKELSQGLKFLRDFLGDGLPTSWTHEKNWKKAHNILLPSFSQQAMKGYHASMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRLNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGVEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPVVNYFALYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASLGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELLTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_528908fa127a17873a6d2a45
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQGLKFLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPPVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELQTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_52e5691cb5516155bc071eee
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGHEATSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLPTVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLSLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAGL
+>seq_541bde7fb942c730a7a2dee1
+MSFVKDFKPQALGDTNLFKPIKIGNNELLHRAVIPPLTRMRALHPGNIPNRDWAVEYYTQRAQRPGTMIITEGAFISPQAGGYDNAPGVWSEEQMVEWTKIFNAIHEKKSFVWVQLWVLGWAAFPDNLARDGLRYDSASDNVFMDAEQEAKAKKANNPQHSLTKDEIKQYIKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNTRTDEYGGSIENRARFTLEVVDALVEAIGHEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVAGELEKRAKAGKRLAFVHLVEPRVTNPFLTEGEGEYEGGSNDFVYSIWKGPVIRAGNFALHPEVVREEVKDKRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFYQMSAHGYIDYPTYEEALKLGWDKK
+>seq_59129bcf78036c2f96817f0a
+MAVPGYDFGKVPDAPISDADFESLKKTVMWGEEDEKYRKMACEALKGQVEDILDLMKGFDGSNQHLIYYFGDKSGRPIPQYLEAVRKRYGLWIIDTLCKPLDRQWLNYMYEIGLRHHRTKKGKTDGVDTVEHIPLRYMIAFIAPIGLTIKPILEKSGHPPEAVERMWAAWVKLVVLQVAIWSYPYAKTGEW
+>seq_5a5b553735be93b8626ca8c2
+MGDILIVWAKDVDEMLKQVEILRRLGAKQIAVESSDWRILQEALKKGGDILIVNGGGMTITFRGDDLEALLKAAIEMIKQALKFGATITLSLDGNDLNINITGVPEQVRKELAKEAERLAKEFGITVTRTGGGDVDEMLKQVEILRRLGAKQIAVESDDWRILQEALKKGGDILIVWAKDVDEMLKQVEILRRLGAKQIAVESSDWRILQEALKKGGDILIVNGGGMTITFRGDDLEALLKAAIEMIKQALKFGATITLSLDGNDLNINITGVPEQVRKELAKEAERLAKEFGITVTRTGGGDVDEMLKQVEILRRLGAKQIAVESDDWRILQEALKKGGSAWSHPQFEK
+>seq_5d9a3881eae9751a10b949ef
+MWFGEFGGQYVPETLVGPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKLNVFRMKLLGANVIPVNSGSRTLKDAGDEALRDWVATFEYTHYLLGSVVGPHPYPTIVRDFQSVIGREAKAQIPEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQIKPSHSIAPGLDVPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKASGNV
+>seq_5ec0dcb7db812779f103c75a
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKELSQGLKFLRDFLGDGLPTSWTHEKNWKKAHNILLPSFSQQAMKGYHASMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRLNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYSGVEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPVVPYFALYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASLGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELLTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_5ee99c51675147e8d1dda33f
+MQNFEIDYVEMYVENLEVAAFSWVDKYAFAVAGTSRSADHRSIALRQGQVTLVLTEPTSDRHPAAAYLQTHGDGVADIAMATSDVAAAYEAAVRAGAEAVRAPGQHSEAAVTTATIGGFGDVVHTLIQRDGTSAELPPGFTGSMDVTNHGKGDVDLLGIDHFAICLNAGDLGPTVEYYERALGFRQIQDDHIVVGAQAMNVTVVQSASGAVTLGLIEPDRNADPGQIDEFLKDHQGAGVQHIAFNSNDAVRAVKALSERGVEFLKTPGAYYDLLGERITLQTHSLDDLRATNVLADEDHGGQLFHILTASTHPRHTIFFEVIERQGAGTYGGSSVKAAVEAVELERTGQSEFGAARR
+>seq_5ef74c731f37bd7e5af9df71
+MTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWGRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGPEKEAI
+>seq_5f8f1dd5153a6478113bcf5a
+MAELPKEMLRAQTNVILLNVLKQGDNYVYGIIKQVKEASNGEMELNEATLYTIFKRLEKDGIISSYWGDESQGGRRKYYRLTEIGHEAMRLGFESWSRVDKIIENLEANKKSEAIKSRWSHPQFEK
+>seq_5ffdfbe09fa078233f5e8d09
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQGLKFLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPIVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETQSLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAGLEHHHHHH
+>seq_6180ebf659dbac99c59c7004
+MAVPGYDFGKVPDAPISDADFESLKKTVMWGEEDEKYRKMACEALKGQVEDILDLMKGFNGSNQHLIYYFGDKSGRPIPQYLEAVRKRYGLWIIDTLCKPLDRQWLNYMYEIGLRHHRTKKGKTDGVDTVEHIPLRYMIAFIAPIGLTIKPILEKSGHPPEAVERMWAAWVKLVVLQVAIWSYPYAKTGEW
+>seq_65a799666ca1421a0826ddc6
+TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIAGELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFVGDGLGTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDTAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPMSPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPKGF
+>seq_65c1c68265f7c15f84e25082
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVIGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRLEHHHHHH
+>seq_6af0d81b3535ddbc28b59d25
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKSLSQGLKFLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLMAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPPVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELVTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_6af272dc038c3ca7bc2327cd
+MWFGEFGGQYVPETLVGPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKLNVFRMKLLGANVIPVNSGSRTLKDAIDEALRDWVATFEYTHYLDGSVVGPHPYPTIVRDFQSVIGREAKAQIPEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQIKPSHSIAPGLDVPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKASGNV
+>seq_6f604ec77a51741581644613
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYLLLGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_6fea94791e776819b3c1006d
+MWFGEFGGQYVPETLVGPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAETGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKMNVFRMKLLGANVIPVNSGSRTLKDAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREAKAQILEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKASGNVLEHHHHHH
+>seq_7068ee572ee196e373d3371a
+MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKHGVTVLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_7112e81bfccad2bce658866c
+MTNLQTFELPTEVTGCAADISLGRALIQAWQKDGIFQIKTDSEQDRKTQEAMAASKQFCKEPLTFKSSCVSDLTYSGYVASGEEVTAGKPDFPEIFTVCKDLSVGDQRVKAGWPCHGPVPWPNNTYQKSMKTFMEELGLAGERLLKLTALGFELPINTFTDLTRDGWHHMVVLRFPPQTSTLSRGIGAHTDYGLLVIAAQDDVGGLYIRPPVEGEKRNRNWLPGESSAGMFEHDEPWTFVTPTPGVWTVFPGDILQFMTGGQLLSTPHKVKLNTRERFACAYFHEPNFEASAYPLFEPSANERIHYGEHFTNMMMRMYPDRITTQRINKENRLAHLEDLKKYSDTRATGS
+>seq_72c72fa0e7d06ffce0abcbf3
+MAEEVSNKQVILKNYVTGYPKESDMEIKNVTIKLKVPEGSNDVVVKNLYLSCDPYMRSRMRKIEGSYVESFAPGSPITGYGVAKVLESGDPKFQKGDLVWGMTGWEEYSIITPTQTLFKIHDKDVPLSYYTGILGMPGMTAYAGFHEVCSPKKGETVFVSAASGAVGQLVGQFAKMLGCYVVGSAGSKEKVDLLKSKFGFDEAFNYKEEQDLSAALKRYFPDGIDIYFENVGGKMLDAVLVNMKLYGRIAVCGMISQYNLEQTEGVHNLFCLITKRIRMEGFLVFDYYHLYPKYLEMVIPQIKAGKVVYVEDVAHGLESAPTALVGLFSGRNIGKQVVMVSRELEHHHHHH
+>seq_74c6d12048036192ff292472
+TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGHVTRYLSSQRLIKEACDESRFDKMLSQQLKSLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSKDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKATGEQSDDLLTQMLNGKDPETGEPLDDVNIRYQIITFLLAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRAALGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKEALTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKDWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAAD
+>seq_754a0b88eefcb260adcacfb0
+MAMITGGELVVRTLIKAGVEHLFGLHGAHIDTIFQACLDHDVPIIDTRHEAAAGHAAEGYARAGAKLGVALVTAGGGFTNAVTPIANAWLDRTPVLFLTGSGALRDDETNTLQAGIDQVAMAAPITKWAHRVMATEHIPRLVMQAIRAALSAPRGPVLLDLPWDILMNQIDEDSVIIPDLVLSAHGARPDPADLDQALALLRKAERPVIVLGSEASRTARKTALSAFVAATGVPVFADYEGLSMLSGLPDAMRGGLVQNLYSFAKADAAPDLVLMLGARFGLNTGHGSGQLIPHSAQVIQVDPDACELGRLQGIALGIVADVGGTIEALAQATAQDAAWPDRGDWCAKVTDLAQERYASIAAKSSSEHALHPFHASQVIAKHVDAGVTVVADGALTYLWLSEVMSRVKPGGFLCHGYLGSMGVGFGTALGAQVADLEAGRRTILVTGDGSVGYSIGEFDTLVRKQLPLIVIIMNNQSWGATLHFQQLAVGPNRVTGTRLENGSYHGVAAAFGADGYHVDSVESFSAALAQALAHNRPACINVAVALDPIPPEELILIGMDPFGSHHHHHH
+>seq_75ae3a83a97a6b8a31e6a8ed
+MTVPSPLADPSIVPDPYPVYADLAQRRPVHWVERLNAWAVLTYADCAAGLKDPRLTADRGTEVLAAKFPGQPLPPDNIFHRWTKNVVMYTDPPLHDALRRSVRAGFTRAAHQHYDQVLQKVAHDLVASIPAGATEIDAVPALAAELPVRSAVHAFGVPEEDLGFLIPRVNTIMTYFSGPKDQPVTQEIILEKLTDLHTYASELLQGMRGKVLPDTVIARLAAAQDGLTETTPEQTVHQLALVFIALFAPTTPGSLSSGTLAFARNPRQVERFLADQACVDNTANEVLRYNASNQFTWRVAAKDVEMGGVRIEAGQTLALFLGSANRDANMFERPNDFDLDRPNSARHLSFGQGVHACLAAQLISLQLKWFYVALLNRFPGIRTAGEPIWNENLEFRSLRSLPLSLR
+>seq_793b780b2796b06bfbeb2e1b
+MWFGEFGGQYVPETLVGPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAGTGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKLNVFRMKLLGANVIPVNSGSRTLKDAIDEALRDWVATFEYTHYLFGSAVGPHPYPTIVRDFQSVIGREAKAQIPEAEGQLPDVIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKASGNVLEHHHHHH
+>seq_7ca0142c542e0e9bf5dee595
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVDGDCNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_7d0e84a2b0e0469d0dd56de8
+MAPTLSEQTRQLVRASVPALQKHSVAISATMYRLLFERYPETRSLFELPERAIHKLASALLAYARSIDNPSALQAAIRRMVLSHARAGVQAVHYPLVWECLRDAIKEVLGPDATETLLQAWKEAYDFLAHLLSTKEAQVYAVLAE
+>seq_84848298911e2f2fe68f3d30
+AIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFFGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_849a15c2d4c68e19769e3cd4
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKELSQGLKFLRDFLGDGLPTSWTHEKNWKKAHNILLPSFSQQAMKGYHASMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRLNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYSGVEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPVVPYFALYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASLGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELQTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_878922a570b9863a02d7fbd5
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWIGYNDLLRDYAGRPTQLYFARRLSEKYGARVYLKREDLLHTGAHKINGAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWTTNLQTTYYVHGSVVGPHPYPIITRNFQKVIGEETKKQIPEKEGRLPDYIVACVGGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIR
+>seq_884aa2e323db59bf0ede8170
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAGTGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIR
+>seq_8a0792def4d2f8b9fa91eb32
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIR
+>seq_8e9203127d9c021519b49682
+MAVPGYDFGKVPDAPISDADFESLKKTVMWGEEDEKYRKMACEALKGQVEDILDLWYGLQGSNQHLIYYFGDKSGRPIPQYLEAVRKRFGLWIIDTLCKPLDRQWLNYMYEIGLRHHRTKKGKTDGVDTVEHIPLRYMIAFIAPIGLTIKPILEKSGHPPEAVERMWAAWVKLVVLQVAIWSYPYAKTGEWLE
+>seq_9016a176f1bbfd418a63231a
+MGSSHHHHHHSSMSNVKQQTAQIVDWLSSTLGKDHQYREDSLSLTANENYPSALVRLTSGSTAGAFYHCSFPFEVPAGEWHFPEPGHMNAIADQVRDLGKTLIGAQAFDWRPNGGSTAEQALMLAACKPGEGFVHFAHRDGGHFALESLAQKMGIEIFHLPVNPTSLLIDVAKLDEMVRRNPHIRIVILDQSFKLRWQPLAEIRSVLPDSCTLTYDMSHDGGLIMGGVFDSPLSCGADIVHGNTHKTIPGPQKGYIGFKSAQHPLLVDTSLWVCPHLQSNCHAEQLPPMWVAFKEMELFGRDYAAQIVSNAKTLARHLHELGLDVTGESFGFTQTHQVHFAVGDLQKALDLCVNSLHAGGIRSTNIEIPGKPGVHGIRLGVQAMTRRGMKEKDFEVVARFIADLYFKKTEPAKVAQQIKEFLQAFPLAPLAYSFDNYLDEELLAAVYQGAQR
+>seq_92a1f142b118683e9ec62d91
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGQVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFAGDGLVTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLMLDTIGLCGFNYRFNSFYRDQPHPFIISQVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDFLTQMLNGKDPETGETLDDGNIRYQIITFLYAGPEATSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPVAPTFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKEGFTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_948feeccc6c4d08316c46fe8
+MAHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIVNNGHTFWVEFDDSQDKAVLKGGPLDGTYRLIFFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSMTTPPLLESVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
+>seq_951332d30e2d60ca1c93f273
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFACVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_96a0e26fe3bd38769f978c5d
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYISSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAFHEAVSGWLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEAIRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRAGIGQQMSLHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSPSTLEHHHHHH
+>seq_9798b6f1bc79f77203ba843f
+TESGTAAQDPEALAAEIGPVKQVSLGEQIDAALAQQGEQLFNTYCTACHRLDERFIGPALRDVTKRRGPVYIMNMMLNPNGMIQRHPVMKQLVQEYGTALPNQALSEEQARAILEYLRQVAENQ
+>seq_98038065bfb59c69a94a7f82
+MYDWFSEMRKKDPVYYDGNIWQVFSYRYTKEVLNNFSKFSSDLTGYHERLEDLRNGKIRFDIPTRYTMLTSDPPLHDELRSMSADIFSPQKLQTLETFIRETTRSLLDSIDPREDDIVKKLAVPLPIIVISKILGLPIEDKEKFKEWSDLVAFRLGKPGEIFELGKKYLELIGYVKDHLNSGTEVVSRVVNSNLSDIEKLGYIILLLIGGNEATTNLISNSVIDFTRFNLWQRIREENLYLKAIEEALRYSPPAMRTVRKTKERVKLGDQTIEEGEYVRVWIASANRDEEVFHDGEKFIPDRNPNPHLSFGSGIHLSLGAPLARLEARIAIEEFSKRFRHIEILDTEKVPNEVLNGYKRLVVRLKSNE
+>seq_98c15bb7ea47a611564e203f
+MKYLLPTAAAGLLLLAAQPAMAHHHHHHQDPEALAAEIGPVKQVSLGEQIDAALAQQGEQLFNTYCTACHRLDERFIGPALRDVTKRRGPVYIMNTMLNPNGMIQRHPVMKQLVQEYGTMDTDEALSEEQARAILEYLRQVAENQ
+>seq_996f2f3e53a7187d0f275ee9
+MPSLFDPIRFGAFTAKNRIWMAPLTRGRATRDHVPTEIMAEYYAQRASAGLIISEATGISQEGLGWPYAPGIWSDAQVEAWLPITQAVHDAGGLIFAQLWHMGRMVPSNVSGMQPVAPSASQAPGLGHTYDGKKPYDVARALRLDEIPRLLDDYEKAARHALKAGFDGVQIHAANGYLIDEFIRDSTNHRHDEYGGAVENRIRLLKDVTERVIATIGKERTAVRLSPNGEIQGTVDSHPEQVFIPAAKMLSDLDIAFLGMREGAVDGTFGKTDQPKLSPEIRKVFKPPLVLNQWYTFETAQAALDSGVADAISFGRPFIGNPDLPRRFFEKAPLTKDVIETWWTQTPKGYTDYPLLGDLEHHHHHH
+>seq_9d0eab3fb86249757e512a79
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFVRDFAGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLTLKPEGFVVKAKSKKIPLGGIPSTHHHHHH
+>seq_9d443d6ef6c4916758e21949
+MASMTGGQQMGRDQAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWVSTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDAVQQ
+>seq_9d63f4b11571e5f41ab7523c
+MAVPGYDFGKVPDAPISDADFESLKKTVMWGEEDEKYRKMACEALKGQVEDILDLFKGFNGSNQHLIYYFGDKSGRPIPQYLEAVRKRYGLWIIDTLCKPLDRQWLNYMYEIGLRHHRTKKGKTDGVDTVEHIPLRYMIAFIAPIGLTIKPILEKSGHPPEAVERMWAAWVKLVVLQVAIWSYPYAKTGEWLE
+>seq_9dc4d8b84f4989d5a0ff8bba
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKSLSQGLKFLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLMAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPPVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELATLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_9f4dfd197c4d380e984add65
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKELSQGLKFLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHASMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRLNSFYRDQPHPFIISLVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGVEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTVPYFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASLGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELITLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_a18dcd7e1dad906a031a2aeb
+MPFVKDFKPQALGDTNLFKPIKIGNNELLHRAVIPPLTRMRAQHPGNIPNRDWAVEYYAQRAQRPGTLIITEGTFPSPQSGGYDNAPGIWSEEQIKEWTKIFKAIHENKSFAWVQLWVLGWAAFPDTLARDGLRYDSASDNVYMNAEQEEKAKKANNPQHSITKDEIKQYVKEYVQAAKNSIAAGADGVEIHSANGYLLNQFLDPHSNNRTDEYGGSIENRARFTLEVVDAVVDAIGPEKVGLRLSPYGVFNSMSGGAETGIVAQYAYVLGELERRAKAGKRLAFVHLVEPRVTNPFLTEGEGEYNGGSNKFAYSIWKGPIIRAGNFALHPEVVREEVKDPRTLIGYGRFFISNPDLVDRLEKGLPLNKYDRDTFYKMSAEGYIDYPTYEEALKLGWDKN
+>seq_a2744863b99e74d192869d7a
+MGSSHHHHHHSSGLVPRGSHMIDLRSDTVTKPTEEMRKAMAQAEVGDDVYGEDPTINELERLAAETFGKEAALFVPSGTMGNQVSIMAHTQRGDEVILEADSHIFWYEVGAMAVLSGVMPHPVPGKNGAMDPDDVRKAIRPRNIHFPRTSLIAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGVPVKEYAGYADSVMFCLSKGLCAPVGSVVVGDRDFIERARKARKMLGGGMRQAGVLAAAGIIALTKMVDRLKEDHENARFLALKLKEIGYSVNPEDVKTNMVILRTDNLKVNAHGFIEALRNSGVLANAVSDTEIRLVTHKDVSRNDIEEALNIFEKLFRKFS
+>seq_a2c96bc702a36bc584aabfb1
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYGSGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACHSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_a45082e7ad53e266be7ca1c8
+MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKVGATALTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
+>seq_a8876f102d5d27bb2318e982
+MTESGTAAQDPEALAAEIGPVKQVSLGEQIDAALAQQGEQLFNTYCTACHRLDERFIGPALRDVTKRRGPVYIMNTMLNPNGMIQRHPVMKQLVQEYGTMMDDEALSEEQARAILEYLRQVAENQLE
+>seq_aa5efdfe0b0107602ab17d21
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQILKFVRDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVPEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFITSMVRALDEAMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKASGEQSDDLLTHMLNGKDPETGEPLDDENIRYQIITFLIAGHETTSGLLSFALYFLVKNPHVLQKAAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTAPAFSLYAKEDTVLGGEYPLEKGDELMVLIPQLHRDKTIWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRACIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETVTLKPTGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAGLEHHHHHH
+>seq_aad0d4885020c72340512c0a
+MIDQKEKELIKESWKRIEPNKNEIGLLFYANLFKEEPTVSVLVQSPISSVSRKAMQVLGILVQGIDNLEGLIPTLQDLGRRHKQYGVVDSHYPLVGDCLLKSIQEYLGQGFTEEAKAAWTKVYGIAAQVMTAEHHHHHH
+>seq_abe5f7fe3c0807025992802a
+MPSLFDPIRFGAFTAKNRIWMAPLTRGRATRDHVPTEIMAEYYAQRASAGLIISEATGISQEGLGWPYAPGIWSDAQVEAWLPITQAVHDAGGLIFAQLWHMGRMVPSNVSGMQPVAPSASQAPGLGHTYDGKKPYDVARALRLDEIPRLLDDYEKAARHALKAGFDGVQIHAANGYLIDEFIRDSTNHRHDEYGGAVENRIRLLKDVTERVIATIGKERTAVRLSPNGEIQGTVDSHPEQVFIPAAKMLSDLDIAFLGMREGAVDGTFGKTDQPKLSPEIRKVFKPPLVLNQDYTFETAQAALDSGVADAISFGRPFIGNPDLPRRFFEKAPLTKDVIETWYTQTPKGYTDYPLLGDHHHHHH
+>seq_ad50006c2cec43fb155f1530
+VLSEGEWQLVLHVWAKVEADVAGHGQEVLIRLFKGHPETLEKFKDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSSATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_ae5f5afa1a429efa46b1871b
+MTSSGVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGATPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVLREVGEAWGRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLAAYHLRRKGVPALYLGPDTPLPDLRALARRLGAGTVVLSAVLSEPLRALPDGALKDLAPRVFLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGPEKEAI
+>seq_b19596b3a7cc32ea02cc78d6
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATAFFRALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_b3661f2577ef49e7685018b2
+MASMTGGQQMGRDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTAGTTEAPAWASTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDAVQQ
+>seq_b3e9664963db1b71ede96254
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAEAAAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_b7b3fc8ec7ee6561e8a9e317
+MERTANPADVPAGGKSSEGKAGTPPAAEAQCPFSKMAADFDAFAGPYQADPAEALRWSRDQLPVFYSPNLGYWVVSRYDDIKAVFRDNILFSPRNALEKITPATPEAMEVLKGYGYAMNRAMINEDEPVHMERRRALMGHFLPDNLEARQEMVRRLTREKIDAFIDSGRVDLVEAMLYEVPLNVALHFLGVPEDDIAILKKFSVAHSVSTWGKPTDEQQVAIAHDVGQFWNYAGKIIEKMRKEPDGTGWMHETIRKNAEMPDIVPDSYVHSMMMAIIVAAHETTSLASAGMFKTLLTHRQAWQDICEDPSLIPNAVEECLRYSGSVVAWRRQATAATRIGGVDIPEGAKLLIVQASGNQDERHFEDGDKFDIYRDNAVDHLTFGHGSHQCMGKNIARMEMRIFLEEMTRRLPHLQLAGQEFTYLSNTSFRGPDHVWVEWDPEKNPERADPSLANGNHRFPVGAPARRDIARKIRIKTVRREADGILGLTIEDAKGRSLPRWSAGAHIEVCVDGFDRKYSLCGRADSRDYDIAVLLEEGGRGGSRRIHEVAAEGLELRLRGPSNLFRLDEQARSYVLIAGGIGITPILAMADHLKALGRDYTIHYCGRSRRSMAFLDRLQADHGERLSVHAGDENRHAELAGIVASLPEGGQIYACGPERMISELEDLTARLPHGTLHFEHFSAQETALDPSKENAFQVELKDSGLTLEVAANVTLLDALLASGIDISCDCREGLCGSCEVEVLEGEIDHRDVVLTRTERAENRRMMSCCSRSVKGGKLKLALLEHHHHHH
+>seq_b842c993f9e9e3e80cffb546
+MPRYLKGWLEDVVQLSLRRPSVHASRQRPIISLNERILEFNKRNITAIIAYYLRKSPSGLDVERDPIEYAKYMEPYAVGLSIKTEEKYFDGSYEMLRKIASSVSIPILMNDFIVKESQIDDAYNLGADTVLLIVEILTERELESLLEYARGYGMEPLILINDENDLDIALRIGARFITIYSMNFETGEINKENQRKLISMIPSNVVKVPLLDFFEPNEIEELRKLGVNAFMISSSLMRNPEKIKELIEGSLEHHHHHH
+>seq_b909866808df15f1f1d441ac
+MTESGTAAQDPEALAAEIGPVKQVSLGEQIDAALAQQGEQLFNTYCTACHRLDERFIGPALRDVTKRRGPVYIMNRMLNPNGMIQRHPVMKQLVQEYGTMMDDTALSEEQARAILEYLRQVAENQLE
+>seq_b9e3ad6bb14ebb97a08d853c
+MASMTGGQQMGRDQAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDAVQQ
+>seq_bac6fdad1c0e60c1c9773828
+MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
+>seq_beba08b4acebe98bf4da82d9
+MGYTVGDYLLDRLHELGIEEIFGVPGDYNLQFLDQIISHKDMKWVGNANELNASYMADGYARTKKAAAFLTTFGVGELSAVNGLAGSYAENLPVVEIVGSPTSKVQNEGKFVHHTLADGDFKHFMKMHEPVTAARTLLTAENATVEIDRVLSALLKERKPVYINLPVDVAAAKAEKPSLPLKKENSTSNTSDQEILNKIQESLKNAKKPIVITGHEIISFGLEKTVTQFISKTKLPITTLNFGKSSVDEALPSFLGIYNGTLSEPNLKEFVESADFILMLGVKLTDSSTGAFTHHLNENKMISLNIDEGKIFNERIQNFDFESLISSLLDLSEIEYKGKYIDKKQEDFVPSNALLSQDRLWQAVENLTQSNETIVAEQGTSFFGASSIFLKSKSHFIGQPLWGSIGYTFPAALGSQIADKESRHLLFIGDGSLQLTVQELGLAIREKINPICFIINNDGYTVEREIHGPNQSYNDIPMWNYSKLPESFGATEDRVVSKIVRTENEFVSVMKEAQADPNRMYWIELILAKEGAPKVLKKMGKLFAEQNKSLEHHHHHH
+>seq_c1b3c7673b6fcafe333fdefa
+TIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQALKFARDFAGDGLFTSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLFAGHEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETLSLKPKGFVVKAKSKKIPLGGIPSPSTLEHHHHHH
+>seq_c212073277b54eb769de9cd8
+VLSEGEWQLVLHVWAKVEADVAGHGQEVLIRLFKGHPETLEKLDKFKHLKSEDEMKASEDLKKAGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPIKYLEFVSEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_c24ed6decd3f7462a3fc4050
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIFFFGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDAIDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDYSGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_c3725670ab00abddafe7d037
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLTQKLKFMRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLMAGSDPVSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPTVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGCGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETQGLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_c4dba1696133cb0266fe3937
+MTEQMTGAQALVRALEHVGVDTVFGIPGGAILPAYDPLYDSTKVRHVLVRHEQGAGHAAEGYAQATGRVGVCMATSGPGATNLVTPIADAYMDSVPIVAITGQKSSKLIGTDAFQEADISGITMPITKHNFLVTNADDIPRTIAEAFHIASTGRPGPVLVDIAKDALQATTTFSWPPVMQLPGYRPVTRPHSKQIREAARLMMEAKRPVFYVGGGVHKARASAELRQLVEMTGIPVVTTLMARGTFPDSHPLHMGMPGMHGSVSAVGALQRSDLLIALGTRFDDRVTGELSSFAPHAKVIHADIDPAEISKNRYADVPIVGDCREVLKELIAAVRQEQSQGRRGDYTEWLKLLNGYKKRYPLGYEQYDDGSLAPQYVMERLSAIVGSEAIYVAGVGQHQMWAAQFISHERPGSFINSGGAGTMGFAIPAAMGAKIGRPDATVWAIDGDGCFQMTNQELATCAIEGVPIKVALINNGNLGMVRQWQTLFYDERYSNTSLQRVKRIPDFVKLAEAYGCVGLRCERPEDVDAVINKAMEINDVPVVIDFIVHEDAMVWPMVPAGTSNDDIKYARDMAPKWESEE
+>seq_c57484b0a5fc64847e6d6a68
+MTPSDIPGYDYGRVEKSPITDLEFDLLKKTVMLGEEDVMYLKKAADVLKDQVDEILDLAGGWVASNEHLIYYFSNPDTGEPIKEYLERVRARFGAWVLDTTCRDYNREWLDYQYEVGLRHHRSKKGVTDGVRTVPNTPLRYLIAGIYPITATIKPLLAKKEGSPEDIEGMYNAWLKSVVLQVAIWSHPYTKENDW
+>seq_c57df8e71ab8b52f95ce8c64
+MENGNGATTNGHVNGNGMDFCMKTEDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAECAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLESLESWNGAPLPIS
+>seq_c80ca871d3107c0f7513cde1
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKTLSQGLKFLRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHASMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKATGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLYAGVEGTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPVVPVFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASPGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKELQTLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFST
+>seq_c92aeda1c0cc239e342018a5
+MTIKEMPQPKTFGELKNLPLLNTDKPVQALMKIADELGEIFKFEAPGRVTRYLSSQRLIKEACDESRFDKNLSQAVKFMRDFLGDGLATSWTHEKNWKKAHNILLPSFSQQAMKGYHAMMVDIAVQLVQKWERLNADEHIEVSEDMTRLTLDTIGLCGFNYRFNSFYRDQPHPFIISMVRALDEVMNKLQRANPDDPAYDENKRQFQEDIKVMNDLVDKIIADRKARGEQSDDLLTQMLNGKDPETGEPLDDGNIRYQIITFLMAGHDPTSGLLSFALYFLVKNPHVLQKVAEEAARVLVDPVPSYKQVKQLKYVGMVLNEALRLWPAVPAFSLYAKEDTVLGGEYPLEKGDEVMVLIPQLHRDKTVWGDDVEEFRPERFENPSAIPQHAFKPFGNGQRASIGQQFALHEATLVLGMMLKHFDFEDHTNYELDIKETFGLKPKGFVVKAKSKKIPLGGIPSPSTEQSAKKVRKKAENAHNTPLLVLYGSNMGTAEGTARDLADIAMSKGFAPQVATLDSHAGNLPREGAVLIVTASYNGHPPDNAKQFVDWLDQASADEVKGVRYSVFGCGDKNWATTYQKVPAFIDETLAAKGAENIADRGEADASDDFEGTYEEWREHMWSDVAAYFNLDIENSEDNKSTLSLQFVDSAADMPLAKMHGAFSTNVVASKELQQPGSARSTRHLEIELPKEASYQEGDHLGVIPRNYEGIVNRVTARFGLDASQQIRLEAEEEKLAHLPLAKTVSVEELLQYVELQDPVTRTQLRAMAAKTVCPPHKVELEALLEKQAYKEQVLAKRLTMLELLEKYPACEMKFSEFIALLPSIRPRYYSISSSPRVDEKQASITVSVVSGEAWSGYGEYKGIASNYLAELQEGDTITCFISTPQSEFTLPKDPETPLIMVGPGTGVAPFRGFVQARKQLKEQGQSLGEAHLYFGCRSPHEDYLYQEELENAQSEGIITLHTAFSRMPNQPKTYVQHVMEQDGKKLIELLDQGAHFYICGDGSQMAPAVEATLMKSYADVHQVSEADARLWLQQLEEKGRYAKDVWAG
+>seq_c93042a088ef46592e9eac1b
+MKGYFGPYGGQYVPEILMGALEELEAAYEGIMKDESFWKEFNDLLRDYAGRPTPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRIIAETGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKVVPVKSGSRTLKDALDEALRDWITNLQTTYYVFGSVVGPHPYPIIVRNFQKVIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEAGGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQVSHSVSAGLDASGVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAYLKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRERIRL
+>seq_cba717bef790579dc1aa43a4
+MTRSANSPFEVAIVGGGITGLALAVGLLKRNVSFTIYERAENFGELGVGITFTPNAQRAMEALDPCVLQSFTNVASAPSGGTINFVDGVREQGSEDPRTSTAALLFQLHVKGGYKACRRCDFVDQIVQHIPKDCVQYRKWLDSIETDHESGRAVLKFRDGEIAHADVVIGCDGIRSQVRASMFGTDELCPRAQYSHQLGYRGMVPLAQATAVLGPEKTSSAVLHTGPGAFVLTIPLAEVHAMHIEAFIMDKEEWPEVQTSSDSKRYVLPATRNEATKAFAEFGPTVRSAVSMFPEKLEKWAVFDMLEAPVPTFAKGRVCLAGDAAHASTPNQGGGAGFGIEDALVLAEVLAVLAEAPNVSGIVASEALAVYSEVRYERSQWLVRSSRRTGELCTWKDRDWGLAAEELSRDIISRSHQLWDHDTAGMVSDALAILGERVRGADTAF
+>seq_cd6452ef8bc6b797bc199fff
+MTTLFDPIKLGDLQLPNRIIMAPLTRCRADEGRVPNALMAEYYVQRASAGLILSEATSVSPMGVGYPDTPGIWNDEQVRGWNNVTKAVHAAGGRIFLQLWHVGRISHPSYLNGELPVAPSAIQPKGHVSLVRPLSDYPTPRALETEEINDIVEAYRSGAENAKAAGFDGVEIHGANGYLLDQFLQSSTNQRTDRYGGSLENRARLLLEVTDAAIEVWGAQRVGVHLAPRADAHDMGDADRAETFTYVARELGKRGIAFICSREREADDSIGPLIKEAFGGPYIVNERFDKASANAALASGKADAVAFGVPFIANPDLPARLAADAPLNEAHPETFYGKGPVGYIDYPRL
+>seq_d7b40929f9f603e01e0525ae
+MVLSEGEWQLVLHVWAKVEADVAGHGQDILIRLFKSHPETLEKVDRFKHLKTEAEMKASEDLKKAGVTFLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_da791aa33d942a68723aae85
+MTESGTAAQDPEALAAEIGPVKQVSLGEQIDAALAQQGEQLFNTYCTACHRLDERFIGPALRDVTKRRGPVYIMNRMLNPNGMIQRHPVMKQLVQEYGTQMYDVALSEEQARAILEYLRQVAENQLE
+>seq_dae01849303cb2e536130cde
+MILKRAYDVTPQKISTDKVRGVRKRVLIGLKDAPNFVMRLFTVEPGGLIDRGSHPWEHEIFVLKGKLTVLKEQGEETVEEGFYIFVEPNEIHGFRNDTDSEVEFLCLIPKEGGE
+>seq_db04c9b986fa2fbe69957b03
+MSTTQTPDLDAIVIGAGFGGIYMLHKLRNDLGLSVRVFEKGGGVGGTWYWNKYPGAKSDTEGFVYRYSFDKELLREYDWTTRYLDQPDVLAYLEHVVERYDLARDIQLNTEVTDAIFDEETELWRVTTAGGETLTARFLVTALGLGSRSNIPDIPGRDSFAGRLVHTNAWPEDLDITGKRVGVIGTGSTGTQFIVAAAKMAEQLTVFQRTPQYCVPSGNGPMDPDEVARIKQNFDSIWDQVRSSTVAFGFEESTVEAMSVSESERQRVFQQAWDKGNGFRFMFGTFCDIATNPEANAAAAAFIRSKIAEIVKDPETARKLTPTDLYAKRPLCNEGYYETYNRDNVSLVSLKETPIEEIVPQGVRTSDGVVHELDVLVFATGFDAVDGNYRAMNLRGRDGRHINEHWTEGPTSYLGVTKAGFPNMFMILGPNGPFTNTPPSIEAQVEWISDLIDKATREGLTTVEPTADAEREWTETCAEIANMTLFPKADSWIFGANIPGKRHAVMFYLGGLGNYRRQLADVADGGYRGFQLRGERAQAVA
+>seq_dd92f9218d455689ed2139f1
+MWFGEFGGQYVPETLVGPLKELEKAYKRFKDDEEFNRQLNYYLKTWAGRPTPLYYAKRLTEKIGGAKVYLKREDLVHGGAHKTNNAIGQALLAKLMGKTRLIAGTGAGQHGVATAMAGALLGMKVDIYMGAEDVERQKLNVYRMKLLGANVIPVNSGSRTVKDAFDEALCDRVATFEYTHYLIGTVWGPHPYPTIVRDFQTVIGREAKAQILEAEGQLPDAIVACVGGGSNAMGIFYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHGMLSYFLQDEEGQIKPSHSIAPGLDHPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAKEMSRDEIIIVNLSGRGDKDLDIVLKASGNV
+>seq_df809ac8b79c00d84a357d5a
+MTQKMDFDAIIIGAGFGGLYSLKKLRDDLNLKVRAFDRATEVGGTWFWNQYPGALSDSETHLYCYSWDKELLQEMEIKRKYISQPDVLAYLKRVADKHDLRKDIQFETGIRSAYFDEENSFWNVTTENDEKFTARFLITALGPLSAPNLPKIKGIETFKGELHHTSRWPKDVTFSGKRVGVIGTGSTGVQVITAIASQVKHLTVFQRSAQYSVPIGNVVMSETDVAKIKENYDQIWENVWNSALGYGLNESTLPTMSVSAEERDKIFEEAWQEGGGFRFMFETFGDIAVDETANIEAQNFIKKKISEIVKDPFVAKKLTPTDLYACKPLCDSGYYEIFNRDNVSLEDVKANPIVEIKEDCVVTADGVEHKLDMLICATGFDAVDGSYKRIDIRGKDGISIKDHWKDGPNSYLGMMVSNFPNMFMVFGPNTPLANSPPIIETQVEWIADLIGYAEDHQINQIEATKDAVDNWTNTCSDIANKTLFAKAKCEIFGANVPGKKNTVYLYMGGLKEYRNQISEVSNNNYKGCLLKQ
+>seq_e3b2fb50c62eeddda2f947f6
+MASMTGGQQMGRDEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTAGTTEALFWQSTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDAVQQ
+>seq_e404740193328ae5ef5cebc2
+MTPSDIPGYDYGRVEKSPITDLEFDLLKKTVMLGEKDVMYLKKAGDVLKDQVDEILDLLAVWRASNEHLIYYFSNPDTGEPIKEYLERVRARFGAWILDTTSRDYNREWLDYQYEVGLRHHRSKKGVTDGVRTVPHIPLRYLIAQIYPLTATIKPFLAKKGGSPEDIEGMYNAWLKSVVLQVAIWSHPYTKENDW
+>seq_e7b80c7861adc0143f8aead0
+MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
+>seq_e8665ea2e9d1861680877916
+MVLSEGEWQLVLHVWAKVEADVAGHGQDITIRLFKSHPETLEKFDRFKHLKTEAEMKASEDLKKVGVTFLTALGAILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGNFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_e8b6065e90d4b953c1210000
+MPGKIDKILIVGGGTAGWMAASYLGKALQGTADITLLQAPDIPTLGVGEATIPNLQTAFFDFLGIPEDEWVRECNASYKVAIKFINWRTAGEGTSEARELDGGPDHFYHSFGLLKYHEQIPLSHYWFDRSYRGKTVEPFDYACYMEPVILDANRSPRRLDGSKVTNYAWHFDAHLVADFLRRFATEKLGVRHVEDRVEHVQRDANGNIESVRTATGRVFDADLFVDCSGFRGLLINKAMEEPFLDMSDHLLNDSAVATQVPHDDDANGVEPFTSAIAMKSGWTWKIPMLGRFGTGYVYSSRFATEDEAVREFCEMWHLDPETQPLNRIRFRVGRNRRAWVGNCVSIGTSSCFVEPLESTGIYFVYAALYQLVKHFPDKSLNPVLTARFNREIETMFDDTRDFIQAHFYFSPRTDTPFWRANKELRLADGMQEKIDMYRAGMAINAPASDDAQLYYGNFEEEFRNFWTNSSYYCVLAGLGLVPDAPSPRLAHMPQATESVDEVFGAVKDRQRNLLETLPSLHEFLRQQHGR
+>seq_e97cc229f406329f1bfee259
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+>seq_e9deb960088a58945012260c
+MYDWFSEMRKKDPVYYDGNIWQVFSYRYTKEVLNNFSKFSSDLTGYHERLEDLRNGKIRFDIPTRYTMLTSDPPLHDELRSMSADIFSPQKLQTLETFIRETTRSLLDSIDPREDDIVKKLAVPLPIIVISKILGLPIEDKEKFKEWSDLVLFRLGKPGEIFELGKKYLELIGYVKDHLNSGTEVVSRVVNSNLSDIEKLGYIILLLFAGNEGTTNLISNSVIDFTRFNLWQRIREENLYLKAIEEALRYSPPAMFTVRKTKERVKLGDQTIEEGEYVRVWIASANRDEEVFHDGEKFIPDRNPNPHLSFGSGIHLGLGAPLARLEARIAIEEFSKRFRHIEILDTEKVPNEVLNGYKRLVVRLKSNE
+>seq_eaf4bc7f7dbb8dd5faf5478a
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+>seq_ebc3635504f18e21dd80bf5d
+MASMTGGQQMGRDQAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWASTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDAVQQ
+>seq_f12977468c45bda3bd195b95
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+>seq_f1ab5492799f42e46ea77e92
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+>seq_f3d8cf013b22974a4879a899
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+>seq_f5492ac1089936805bdbc95a
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+>seq_f60c67db6ce1aa44b4a6cd57
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+>seq_f6f3a46fd07322ce8b3ca6dc
+VLSEGEWQLVLHVWAKVEADVAGHGQEVSIRLFKGHPETLEKFKDKFKHLKSEDEMKASEDLKKVGATFLTALGGILKKKGHHEAEIKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQGAMNKALELFRKDIAAKYKELGYQG
+>seq_fbedff276629f842fbd40a33
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+>seq_fe026b8204820ec918b95f46
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data/enzengdb-v1/ranker-three-seed-summary.json

@@ -0,0 +1,75 @@
+{
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+  "bootstrap_seed": 42,
+  "campaign_count": 51,
+  "claim_boundary": "Seed variation and campaign-bootstrap uncertainty for within-campaign ranking. Intervals do not convert heterogeneous fitness endpoints into absolute activity.",
+  "inputs": [
+    "<redacted-local-path>",
+    "<redacted-local-path>",
+    "<redacted-local-path>"
+  ],
+  "metrics": {
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+    "row_count": 6423,
+    "sha256": "8e76932fc76b884ea8cf127934683b43b9e896b057b817488a9dc5533cf1fc4b",
+    "size_bytes": 167712
+  }
+}

data/enzengdb-v1/zero-shot-kcat-proxy.json

@@ -0,0 +1,538 @@
+{
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data/full-homology-baseline/test_metrics.json

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data/lunzer-imdh/homology-audit.json

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data/lunzer-imdh/selection.json

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+    "lunzer-DDYVYR-nad",
+    "lunzer-DDYVYR-nadp",
+    "lunzer-DDYVYS-nad",
+    "lunzer-DDYVYS-nadp",
+    "lunzer-DEFAGR-nad",
+    "lunzer-DEFAGR-nadp",
+    "lunzer-DEFAGS-nad",
+    "lunzer-DEFAGS-nadp",
+    "lunzer-DEFAYR-nad",
+    "lunzer-DEFAYR-nadp",
+    "lunzer-DEFAYS-nad",
+    "lunzer-DEFAYS-nadp",
+    "lunzer-DEFVGR-nad",
+    "lunzer-DEFVGR-nadp",
+    "lunzer-DEFVGS-nad",
+    "lunzer-DEFVGS-nadp",
+    "lunzer-DEFVYR-nad",
+    "lunzer-DEFVYR-nadp",
+    "lunzer-DEFVYS-nad",
+    "lunzer-DEFVYS-nadp",
+    "lunzer-DEHAGR-nad",
+    "lunzer-DEHAGR-nadp",
+    "lunzer-DEHAGS-nad",
+    "lunzer-DEHAGS-nadp",
+    "lunzer-DEHAYR-nad",
+    "lunzer-DEHAYR-nadp",
+    "lunzer-DEHAYS-nad",
+    "lunzer-DEHAYS-nadp",
+    "lunzer-DEHVGR-nad",
+    "lunzer-DEHVGR-nadp",
+    "lunzer-DEHVGS-nad",
+    "lunzer-DEHVGS-nadp",
+    "lunzer-DEHVYR-nad",
+    "lunzer-DEHVYR-nadp",
+    "lunzer-DEHVYS-nad",
+    "lunzer-DEHVYS-nadp",
+    "lunzer-DEIAGR-nad",
+    "lunzer-DEIAGR-nadp",
+    "lunzer-DEIAGS-nad",
+    "lunzer-DEIAGS-nadp",
+    "lunzer-DEIAYR-nad",
+    "lunzer-DEIAYR-nadp",
+    "lunzer-DEIAYS-nad",
+    "lunzer-DEIAYS-nadp",
+    "lunzer-DEIVGR-nad",
+    "lunzer-DEIVGR-nadp",
+    "lunzer-DEIVGS-nad",
+    "lunzer-DEIVGS-nadp",
+    "lunzer-DEIVYR-nad",
+    "lunzer-DEIVYR-nadp",
+    "lunzer-DEIVYS-nad",
+    "lunzer-DEIVYS-nadp",
+    "lunzer-DEKAGR-nad",
+    "lunzer-DEKAGR-nadp",
+    "lunzer-DEKAGS-nad",
+    "lunzer-DEKAGS-nadp",
+    "lunzer-DEKAYR-nad",
+    "lunzer-DEKAYR-nadp",
+    "lunzer-DEKAYS-nad",
+    "lunzer-DEKAYS-nadp",
+    "lunzer-DEKVGR-nad",
+    "lunzer-DEKVGR-nadp",
+    "lunzer-DEKVGS-nad",
+    "lunzer-DEKVGS-nadp",
+    "lunzer-DEKVYR-nad",
+    "lunzer-DEKVYR-nadp",
+    "lunzer-DEKVYS-nad",
+    "lunzer-DEKVYS-nadp",
+    "lunzer-DELAGR-nad",
+    "lunzer-DELAGR-nadp",
+    "lunzer-DELAGS-nad",
+    "lunzer-DELAGS-nadp",
+    "lunzer-DELAYR-nad",
+    "lunzer-DELAYR-nadp",
+    "lunzer-DELAYS-nad",
+    "lunzer-DELAYS-nadp",
+    "lunzer-DELVGR-nad",
+    "lunzer-DELVGR-nadp",
+    "lunzer-DELVGS-nad",
+    "lunzer-DELVGS-nadp",
+    "lunzer-DELVYR-nad",
+    "lunzer-DELVYR-nadp",
+    "lunzer-DELVYS-nad",
+    "lunzer-DELVYS-nadp",
+    "lunzer-DENAGR-nad",
+    "lunzer-DENAGR-nadp",
+    "lunzer-DENAGS-nad",
+    "lunzer-DENAGS-nadp",
+    "lunzer-DENAYR-nad",
+    "lunzer-DENAYR-nadp",
+    "lunzer-DENAYS-nad",
+    "lunzer-DENAYS-nadp",
+    "lunzer-DENVGR-nad",
+    "lunzer-DENVGR-nadp",
+    "lunzer-DENVGS-nad",
+    "lunzer-DENVGS-nadp",
+    "lunzer-DENVYR-nad",
+    "lunzer-DENVYR-nadp",
+    "lunzer-DENVYS-nad",
+    "lunzer-DENVYS-nadp",
+    "lunzer-DEQAGR-nad",
+    "lunzer-DEQAGR-nadp",
+    "lunzer-DEQAGS-nad",
+    "lunzer-DEQAGS-nadp",
+    "lunzer-DEQAYR-nad",
+    "lunzer-DEQAYR-nadp",
+    "lunzer-DEQAYS-nad",
+    "lunzer-DEQAYS-nadp",
+    "lunzer-DEQVGR-nad",
+    "lunzer-DEQVGR-nadp",
+    "lunzer-DEQVGS-nad",
+    "lunzer-DEQVGS-nadp",
+    "lunzer-DEQVYR-nad",
+    "lunzer-DEQVYR-nadp",
+    "lunzer-DEQVYS-nad",
+    "lunzer-DEQVYS-nadp",
+    "lunzer-DEYAGR-nad",
+    "lunzer-DEYAGR-nadp",
+    "lunzer-DEYAGS-nad",
+    "lunzer-DEYAGS-nadp",
+    "lunzer-DEYAYR-nad",
+    "lunzer-DEYAYR-nadp",
+    "lunzer-DEYAYS-nad",
+    "lunzer-DEYAYS-nadp",
+    "lunzer-DEYVGR-nad",
+    "lunzer-DEYVGR-nadp",
+    "lunzer-DEYVGS-nad",
+    "lunzer-DEYVGS-nadp",
+    "lunzer-DEYVYR-nad",
+    "lunzer-DEYVYR-nadp",
+    "lunzer-DEYVYS-nad",
+    "lunzer-DEYVYS-nadp",
+    "lunzer-DKFAGR-nad",
+    "lunzer-DKFAGR-nadp",
+    "lunzer-DKFAGS-nad",
+    "lunzer-DKFAGS-nadp",
+    "lunzer-DKFAYR-nad",
+    "lunzer-DKFAYR-nadp",
+    "lunzer-DKFAYS-nad",
+    "lunzer-DKFAYS-nadp",
+    "lunzer-DKFVGR-nad",
+    "lunzer-DKFVGR-nadp",
+    "lunzer-DKFVGS-nad",
+    "lunzer-DKFVGS-nadp",
+    "lunzer-DKFVYR-nad",
+    "lunzer-DKFVYR-nadp",
+    "lunzer-DKFVYS-nad",
+    "lunzer-DKFVYS-nadp",
+    "lunzer-DKHAGR-nad",
+    "lunzer-DKHAGR-nadp",
+    "lunzer-DKHAGS-nad",
+    "lunzer-DKHAGS-nadp",
+    "lunzer-DKHAYR-nad",
+    "lunzer-DKHAYR-nadp",
+    "lunzer-DKHAYS-nad",
+    "lunzer-DKHAYS-nadp",
+    "lunzer-DKHVGR-nad",
+    "lunzer-DKHVGR-nadp",
+    "lunzer-DKHVGS-nad",
+    "lunzer-DKHVGS-nadp",
+    "lunzer-DKHVYR-nad",
+    "lunzer-DKHVYR-nadp",
+    "lunzer-DKHVYS-nad",
+    "lunzer-DKHVYS-nadp",
+    "lunzer-DKIAGR-nad",
+    "lunzer-DKIAGR-nadp",
+    "lunzer-DKIAGS-nad",
+    "lunzer-DKIAGS-nadp",
+    "lunzer-DKIAYR-nad",
+    "lunzer-DKIAYR-nadp",
+    "lunzer-DKIAYS-nad",
+    "lunzer-DKIAYS-nadp",
+    "lunzer-DKIVGR-nad",
+    "lunzer-DKIVGR-nadp",
+    "lunzer-DKIVGS-nad",
+    "lunzer-DKIVGS-nadp",
+    "lunzer-DKIVYR-nad",
+    "lunzer-DKIVYR-nadp",
+    "lunzer-DKIVYS-nad",
+    "lunzer-DKIVYS-nadp",
+    "lunzer-DKKAGR-nad",
+    "lunzer-DKKAGR-nadp",
+    "lunzer-DKKAGS-nad",
+    "lunzer-DKKAGS-nadp",
+    "lunzer-DKKAYR-nad",
+    "lunzer-DKKAYR-nadp",
+    "lunzer-DKKAYS-nad",
+    "lunzer-DKKAYS-nadp",
+    "lunzer-DKKVGR-nad",
+    "lunzer-DKKVGR-nadp",
+    "lunzer-DKKVGS-nad",
+    "lunzer-DKKVGS-nadp",
+    "lunzer-DKKVYR-nad",
+    "lunzer-DKKVYR-nadp",
+    "lunzer-DKKVYS-nad",
+    "lunzer-DKKVYS-nadp",
+    "lunzer-DKLAGR-nad",
+    "lunzer-DKLAGR-nadp",
+    "lunzer-DKLAGS-nad",
+    "lunzer-DKLAGS-nadp",
+    "lunzer-DKLAYR-nad",
+    "lunzer-DKLAYR-nadp",
+    "lunzer-DKLAYS-nad",
+    "lunzer-DKLAYS-nadp",
+    "lunzer-DKLVGR-nad",
+    "lunzer-DKLVGR-nadp",
+    "lunzer-DKLVGS-nad",
+    "lunzer-DKLVGS-nadp",
+    "lunzer-DKLVYR-nad",
+    "lunzer-DKLVYR-nadp",
+    "lunzer-DKLVYS-nad",
+    "lunzer-DKLVYS-nadp",
+    "lunzer-DKNAGR-nad",
+    "lunzer-DKNAGR-nadp",
+    "lunzer-DKNAGS-nad",
+    "lunzer-DKNAGS-nadp",
+    "lunzer-DKNAYR-nad",
+    "lunzer-DKNAYR-nadp",
+    "lunzer-DKNAYS-nad",
+    "lunzer-DKNAYS-nadp",
+    "lunzer-DKNVGR-nad",
+    "lunzer-DKNVGR-nadp",
+    "lunzer-DKNVGS-nad",
+    "lunzer-DKNVGS-nadp",
+    "lunzer-DKNVYR-nad",
+    "lunzer-DKNVYR-nadp",
+    "lunzer-DKNVYS-nad",
+    "lunzer-DKNVYS-nadp",
+    "lunzer-DKQAGR-nad",
+    "lunzer-DKQAGR-nadp",
+    "lunzer-DKQAGS-nad",
+    "lunzer-DKQAGS-nadp",
+    "lunzer-DKQAYR-nad",
+    "lunzer-DKQAYR-nadp",
+    "lunzer-DKQAYS-nad",
+    "lunzer-DKQAYS-nadp",
+    "lunzer-DKQVGR-nad",
+    "lunzer-DKQVGR-nadp",
+    "lunzer-DKQVGS-nad",
+    "lunzer-DKQVGS-nadp",
+    "lunzer-DKQVYR-nad",
+    "lunzer-DKQVYR-nadp",
+    "lunzer-DKQVYS-nad",
+    "lunzer-DKQVYS-nadp",
+    "lunzer-DKYAGR-nad",
+    "lunzer-DKYAGR-nadp",
+    "lunzer-DKYAGS-nad",
+    "lunzer-DKYAGS-nadp",
+    "lunzer-DKYAYR-nad",
+    "lunzer-DKYAYR-nadp",
+    "lunzer-DKYAYS-nad",
+    "lunzer-DKYAYS-nadp",
+    "lunzer-DKYVGR-nad",
+    "lunzer-DKYVGR-nadp",
+    "lunzer-DKYVGS-nad",
+    "lunzer-DKYVGS-nadp",
+    "lunzer-DKYVYR-nad",
+    "lunzer-DKYVYR-nadp",
+    "lunzer-DKYVYS-nad",
+    "lunzer-DKYVYS-nadp",
+    "lunzer-DNFAGR-nad",
+    "lunzer-DNFAGR-nadp",
+    "lunzer-DNFAGS-nad",
+    "lunzer-DNFAGS-nadp",
+    "lunzer-DNFAYR-nad",
+    "lunzer-DNFAYR-nadp",
+    "lunzer-DNFAYS-nad",
+    "lunzer-DNFAYS-nadp",
+    "lunzer-DNFVGR-nad",
+    "lunzer-DNFVGR-nadp",
+    "lunzer-DNFVGS-nad",
+    "lunzer-DNFVGS-nadp",
+    "lunzer-DNFVYR-nad",
+    "lunzer-DNFVYR-nadp",
+    "lunzer-DNFVYS-nad",
+    "lunzer-DNFVYS-nadp",
+    "lunzer-DNHAGR-nad",
+    "lunzer-DNHAGR-nadp",
+    "lunzer-DNHAGS-nad",
+    "lunzer-DNHAGS-nadp",
+    "lunzer-DNHAYR-nad",
+    "lunzer-DNHAYR-nadp",
+    "lunzer-DNHAYS-nad",
+    "lunzer-DNHAYS-nadp",
+    "lunzer-DNHVGR-nad",
+    "lunzer-DNHVGR-nadp",
+    "lunzer-DNHVGS-nad",
+    "lunzer-DNHVGS-nadp",
+    "lunzer-DNHVYR-nad",
+    "lunzer-DNHVYR-nadp",
+    "lunzer-DNHVYS-nad",
+    "lunzer-DNHVYS-nadp",
+    "lunzer-DNIAGR-nad",
+    "lunzer-DNIAGR-nadp",
+    "lunzer-DNIAGS-nad",
+    "lunzer-DNIAGS-nadp",
+    "lunzer-DNIAYR-nad",
+    "lunzer-DNIAYR-nadp",
+    "lunzer-DNIAYS-nad",
+    "lunzer-DNIAYS-nadp",
+    "lunzer-DNIVGR-nad",
+    "lunzer-DNIVGR-nadp",
+    "lunzer-DNIVGS-nad",
+    "lunzer-DNIVGS-nadp",
+    "lunzer-DNIVYR-nad",
+    "lunzer-DNIVYR-nadp",
+    "lunzer-DNIVYS-nad",
+    "lunzer-DNIVYS-nadp",
+    "lunzer-DNKAGR-nad",
+    "lunzer-DNKAGR-nadp",
+    "lunzer-DNKAGS-nad",
+    "lunzer-DNKAGS-nadp",
+    "lunzer-DNKAYR-nad",
+    "lunzer-DNKAYR-nadp",
+    "lunzer-DNKAYS-nad",
+    "lunzer-DNKAYS-nadp",
+    "lunzer-DNKVGR-nad",
+    "lunzer-DNKVGR-nadp",
+    "lunzer-DNKVGS-nad",
+    "lunzer-DNKVGS-nadp",
+    "lunzer-DNKVYR-nad",
+    "lunzer-DNKVYR-nadp",
+    "lunzer-DNKVYS-nad",
+    "lunzer-DNKVYS-nadp",
+    "lunzer-DNLAGR-nad",
+    "lunzer-DNLAGR-nadp",
+    "lunzer-DNLAGS-nad",
+    "lunzer-DNLAGS-nadp",
+    "lunzer-DNLAYR-nad",
+    "lunzer-DNLAYR-nadp",
+    "lunzer-DNLAYS-nad",
+    "lunzer-DNLAYS-nadp",
+    "lunzer-DNLVGR-nad",
+    "lunzer-DNLVGR-nadp",
+    "lunzer-DNLVGS-nad",
+    "lunzer-DNLVGS-nadp",
+    "lunzer-DNLVYR-nad",
+    "lunzer-DNLVYR-nadp",
+    "lunzer-DNLVYS-nad",
+    "lunzer-DNLVYS-nadp",
+    "lunzer-DNNAGR-nad",
+    "lunzer-DNNAGR-nadp",
+    "lunzer-DNNAGS-nad",
+    "lunzer-DNNAGS-nadp",
+    "lunzer-DNNAYR-nad",
+    "lunzer-DNNAYR-nadp",
+    "lunzer-DNNAYS-nad",
+    "lunzer-DNNAYS-nadp",
+    "lunzer-DNNVGR-nad",
+    "lunzer-DNNVGR-nadp",
+    "lunzer-DNNVGS-nad",
+    "lunzer-DNNVGS-nadp",
+    "lunzer-DNNVYR-nad",
+    "lunzer-DNNVYR-nadp",
+    "lunzer-DNNVYS-nad",
+    "lunzer-DNNVYS-nadp",
+    "lunzer-DNQAGR-nad",
+    "lunzer-DNQAGR-nadp",
+    "lunzer-DNQAGS-nad",
+    "lunzer-DNQAGS-nadp",
+    "lunzer-DNQAYR-nad",
+    "lunzer-DNQAYR-nadp",
+    "lunzer-DNQAYS-nad",
+    "lunzer-DNQAYS-nadp",
+    "lunzer-DNQVGR-nad",
+    "lunzer-DNQVGR-nadp",
+    "lunzer-DNQVGS-nad",
+    "lunzer-DNQVGS-nadp",
+    "lunzer-DNQVYR-nad",
+    "lunzer-DNQVYR-nadp",
+    "lunzer-DNQVYS-nad",
+    "lunzer-DNQVYS-nadp",
+    "lunzer-DNYAGR-nad",
+    "lunzer-DNYAGR-nadp",
+    "lunzer-DNYAGS-nad",
+    "lunzer-DNYAGS-nadp",
+    "lunzer-DNYAYR-nad",
+    "lunzer-DNYAYR-nadp",
+    "lunzer-DNYAYS-nad",
+    "lunzer-DNYAYS-nadp",
+    "lunzer-DNYVGR-nad",
+    "lunzer-DNYVGR-nadp",
+    "lunzer-DNYVGS-nad",
+    "lunzer-DNYVGS-nadp",
+    "lunzer-DNYVYR-nad",
+    "lunzer-DNYVYR-nadp",
+    "lunzer-DNYVYS-nad",
+    "lunzer-DNYVYS-nadp",
+    "lunzer-RDFAGR-nad",
+    "lunzer-RDFAGR-nadp",
+    "lunzer-RDFAGS-nad",
+    "lunzer-RDFAGS-nadp",
+    "lunzer-RDFAYR-nad",
+    "lunzer-RDFAYR-nadp",
+    "lunzer-RDFAYS-nad",
+    "lunzer-RDFAYS-nadp",
+    "lunzer-RDFVGR-nad",
+    "lunzer-RDFVGR-nadp",
+    "lunzer-RDFVGS-nad",
+    "lunzer-RDFVGS-nadp",
+    "lunzer-RDFVYR-nad",
+    "lunzer-RDFVYR-nadp",
+    "lunzer-RDFVYS-nad",
+    "lunzer-RDFVYS-nadp",
+    "lunzer-RDHAGR-nad",
+    "lunzer-RDHAGR-nadp",
+    "lunzer-RDHAGS-nad",
+    "lunzer-RDHAGS-nadp",
+    "lunzer-RDHAYR-nad",
+    "lunzer-RDHAYR-nadp",
+    "lunzer-RDHAYS-nad",
+    "lunzer-RDHAYS-nadp",
+    "lunzer-RDHVGR-nad",
+    "lunzer-RDHVGR-nadp",
+    "lunzer-RDHVGS-nad",
+    "lunzer-RDHVGS-nadp",
+    "lunzer-RDHVYR-nad",
+    "lunzer-RDHVYR-nadp",
+    "lunzer-RDHVYS-nad",
+    "lunzer-RDHVYS-nadp",
+    "lunzer-RDIAGR-nad",
+    "lunzer-RDIAGR-nadp",
+    "lunzer-RDIAGS-nad",
+    "lunzer-RDIAGS-nadp",
+    "lunzer-RDIAYR-nad",
+    "lunzer-RDIAYR-nadp",
+    "lunzer-RDIAYS-nad",
+    "lunzer-RDIAYS-nadp",
+    "lunzer-RDIVGR-nad",
+    "lunzer-RDIVGR-nadp",
+    "lunzer-RDIVGS-nad",
+    "lunzer-RDIVGS-nadp",
+    "lunzer-RDIVYR-nad",
+    "lunzer-RDIVYR-nadp",
+    "lunzer-RDIVYS-nad",
+    "lunzer-RDIVYS-nadp",
+    "lunzer-RDKAGR-nad",
+    "lunzer-RDKAGR-nadp",
+    "lunzer-RDKAGS-nad",
+    "lunzer-RDKAGS-nadp",
+    "lunzer-RDKAYR-nad",
+    "lunzer-RDKAYR-nadp",
+    "lunzer-RDKAYS-nad",
+    "lunzer-RDKAYS-nadp",
+    "lunzer-RDKVGR-nad",
+    "lunzer-RDKVGR-nadp",
+    "lunzer-RDKVGS-nad",
+    "lunzer-RDKVGS-nadp",
+    "lunzer-RDKVYR-nad",
+    "lunzer-RDKVYR-nadp",
+    "lunzer-RDKVYS-nad",
+    "lunzer-RDKVYS-nadp",
+    "lunzer-RDLAGR-nad",
+    "lunzer-RDLAGR-nadp",
+    "lunzer-RDLAGS-nad",
+    "lunzer-RDLAGS-nadp",
+    "lunzer-RDLAYR-nad",
+    "lunzer-RDLAYR-nadp",
+    "lunzer-RDLAYS-nad",
+    "lunzer-RDLAYS-nadp",
+    "lunzer-RDLVGR-nad",
+    "lunzer-RDLVGR-nadp",
+    "lunzer-RDLVGS-nad",
+    "lunzer-RDLVGS-nadp",
+    "lunzer-RDLVYR-nad",
+    "lunzer-RDLVYR-nadp",
+    "lunzer-RDLVYS-nad",
+    "lunzer-RDLVYS-nadp",
+    "lunzer-RDNAGR-nad",
+    "lunzer-RDNAGR-nadp",
+    "lunzer-RDNAGS-nad",
+    "lunzer-RDNAGS-nadp",
+    "lunzer-RDNAYR-nad",
+    "lunzer-RDNAYR-nadp",
+    "lunzer-RDNAYS-nad",
+    "lunzer-RDNAYS-nadp",
+    "lunzer-RDNVGR-nad",
+    "lunzer-RDNVGR-nadp",
+    "lunzer-RDNVGS-nad",
+    "lunzer-RDNVGS-nadp",
+    "lunzer-RDNVYR-nad",
+    "lunzer-RDNVYR-nadp",
+    "lunzer-RDNVYS-nad",
+    "lunzer-RDNVYS-nadp",
+    "lunzer-RDQAGR-nad",
+    "lunzer-RDQAGR-nadp",
+    "lunzer-RDQAGS-nad",
+    "lunzer-RDQAGS-nadp",
+    "lunzer-RDQAYR-nad",
+    "lunzer-RDQAYR-nadp",
+    "lunzer-RDQAYS-nad",
+    "lunzer-RDQAYS-nadp",
+    "lunzer-RDQVGR-nad",
+    "lunzer-RDQVGR-nadp",
+    "lunzer-RDQVGS-nad",
+    "lunzer-RDQVGS-nadp",
+    "lunzer-RDQVYR-nad",
+    "lunzer-RDQVYR-nadp",
+    "lunzer-RDQVYS-nad",
+    "lunzer-RDQVYS-nadp",
+    "lunzer-RDYAGR-nad",
+    "lunzer-RDYAGR-nadp",
+    "lunzer-RDYAGS-nad",
+    "lunzer-RDYAGS-nadp",
+    "lunzer-RDYAYR-nad",
+    "lunzer-RDYAYR-nadp",
+    "lunzer-RDYAYS-nad",
+    "lunzer-RDYAYS-nadp",
+    "lunzer-RDYVGR-nad",
+    "lunzer-RDYVGR-nadp",
+    "lunzer-RDYVGS-nad",
+    "lunzer-RDYVGS-nadp",
+    "lunzer-RDYVYR-nad",
+    "lunzer-RDYVYR-nadp",
+    "lunzer-RDYVYS-nad",
+    "lunzer-RDYVYS-nadp",
+    "lunzer-REFAGR-nad",
+    "lunzer-REFAGR-nadp",
+    "lunzer-REFAGS-nad",
+    "lunzer-REFAGS-nadp",
+    "lunzer-REFAYR-nad",
+    "lunzer-REFAYR-nadp",
+    "lunzer-REFAYS-nad",
+    "lunzer-REFAYS-nadp",
+    "lunzer-REFVGR-nad",
+    "lunzer-REFVGR-nadp",
+    "lunzer-REFVGS-nad",
+    "lunzer-REFVGS-nadp",
+    "lunzer-REFVYR-nad",
+    "lunzer-REFVYR-nadp",
+    "lunzer-REFVYS-nad",
+    "lunzer-REFVYS-nadp",
+    "lunzer-REHAGR-nad",
+    "lunzer-REHAGR-nadp",
+    "lunzer-REHAGS-nad",
+    "lunzer-REHAGS-nadp",
+    "lunzer-REHAYR-nad",
+    "lunzer-REHAYR-nadp",
+    "lunzer-REHAYS-nad",
+    "lunzer-REHAYS-nadp",
+    "lunzer-REHVGR-nad",
+    "lunzer-REHVGR-nadp",
+    "lunzer-REHVGS-nad",
+    "lunzer-REHVGS-nadp",
+    "lunzer-REHVYR-nad",
+    "lunzer-REHVYR-nadp",
+    "lunzer-REHVYS-nad",
+    "lunzer-REHVYS-nadp",
+    "lunzer-REIAGR-nad",
+    "lunzer-REIAGR-nadp",
+    "lunzer-REIAGS-nad",
+    "lunzer-REIAGS-nadp",
+    "lunzer-REIAYR-nad",
+    "lunzer-REIAYR-nadp",
+    "lunzer-REIAYS-nad",
+    "lunzer-REIAYS-nadp",
+    "lunzer-REIVGR-nad",
+    "lunzer-REIVGR-nadp",
+    "lunzer-REIVGS-nad",
+    "lunzer-REIVGS-nadp",
+    "lunzer-REIVYR-nad",
+    "lunzer-REIVYR-nadp",
+    "lunzer-REIVYS-nad",
+    "lunzer-REIVYS-nadp",
+    "lunzer-REKAGR-nad",
+    "lunzer-REKAGR-nadp",
+    "lunzer-REKAGS-nad",
+    "lunzer-REKAGS-nadp",
+    "lunzer-REKAYR-nad",
+    "lunzer-REKAYR-nadp",
+    "lunzer-REKAYS-nad",
+    "lunzer-REKAYS-nadp",
+    "lunzer-REKVGR-nad",
+    "lunzer-REKVGR-nadp",
+    "lunzer-REKVGS-nad",
+    "lunzer-REKVGS-nadp",
+    "lunzer-REKVYR-nad",
+    "lunzer-REKVYR-nadp",
+    "lunzer-REKVYS-nad",
+    "lunzer-REKVYS-nadp",
+    "lunzer-RELAGR-nad",
+    "lunzer-RELAGR-nadp",
+    "lunzer-RELAGS-nad",
+    "lunzer-RELAGS-nadp",
+    "lunzer-RELAYR-nad",
+    "lunzer-RELAYR-nadp",
+    "lunzer-RELAYS-nad",
+    "lunzer-RELAYS-nadp",
+    "lunzer-RELVGR-nad",
+    "lunzer-RELVGR-nadp",
+    "lunzer-RELVGS-nad",
+    "lunzer-RELVGS-nadp",
+    "lunzer-RELVYR-nad",
+    "lunzer-RELVYR-nadp",
+    "lunzer-RELVYS-nad",
+    "lunzer-RELVYS-nadp",
+    "lunzer-RENAGR-nad",
+    "lunzer-RENAGR-nadp",
+    "lunzer-RENAGS-nad",
+    "lunzer-RENAGS-nadp",
+    "lunzer-RENAYR-nad",
+    "lunzer-RENAYR-nadp",
+    "lunzer-RENAYS-nad",
+    "lunzer-RENAYS-nadp",
+    "lunzer-RENVGR-nad",
+    "lunzer-RENVGR-nadp",
+    "lunzer-RENVGS-nad",
+    "lunzer-RENVGS-nadp",
+    "lunzer-RENVYR-nad",
+    "lunzer-RENVYR-nadp",
+    "lunzer-RENVYS-nad",
+    "lunzer-RENVYS-nadp",
+    "lunzer-REQAGR-nad",
+    "lunzer-REQAGR-nadp",
+    "lunzer-REQAGS-nad",
+    "lunzer-REQAGS-nadp",
+    "lunzer-REQAYR-nad",
+    "lunzer-REQAYR-nadp",
+    "lunzer-REQAYS-nad",
+    "lunzer-REQAYS-nadp",
+    "lunzer-REQVGR-nad",
+    "lunzer-REQVGR-nadp",
+    "lunzer-REQVGS-nad",
+    "lunzer-REQVGS-nadp",
+    "lunzer-REQVYR-nad",
+    "lunzer-REQVYR-nadp",
+    "lunzer-REQVYS-nad",
+    "lunzer-REQVYS-nadp",
+    "lunzer-REYAGR-nad",
+    "lunzer-REYAGR-nadp",
+    "lunzer-REYAGS-nad",
+    "lunzer-REYAGS-nadp",
+    "lunzer-REYAYR-nad",
+    "lunzer-REYAYR-nadp",
+    "lunzer-REYAYS-nad",
+    "lunzer-REYAYS-nadp",
+    "lunzer-REYVGR-nad",
+    "lunzer-REYVGR-nadp",
+    "lunzer-REYVGS-nad",
+    "lunzer-REYVGS-nadp",
+    "lunzer-REYVYR-nad",
+    "lunzer-REYVYR-nadp",
+    "lunzer-REYVYS-nad",
+    "lunzer-REYVYS-nadp",
+    "lunzer-RKFAGR-nad",
+    "lunzer-RKFAGR-nadp",
+    "lunzer-RKFAGS-nad",
+    "lunzer-RKFAGS-nadp",
+    "lunzer-RKFAYR-nad",
+    "lunzer-RKFAYR-nadp",
+    "lunzer-RKFAYS-nad",
+    "lunzer-RKFAYS-nadp",
+    "lunzer-RKFVGR-nad",
+    "lunzer-RKFVGR-nadp",
+    "lunzer-RKFVGS-nad",
+    "lunzer-RKFVGS-nadp",
+    "lunzer-RKFVYR-nad",
+    "lunzer-RKFVYR-nadp",
+    "lunzer-RKFVYS-nad",
+    "lunzer-RKFVYS-nadp",
+    "lunzer-RKHAGR-nad",
+    "lunzer-RKHAGR-nadp",
+    "lunzer-RKHAGS-nad",
+    "lunzer-RKHAGS-nadp",
+    "lunzer-RKHAYR-nad",
+    "lunzer-RKHAYR-nadp",
+    "lunzer-RKHAYS-nad",
+    "lunzer-RKHAYS-nadp",
+    "lunzer-RKHVGR-nad",
+    "lunzer-RKHVGR-nadp",
+    "lunzer-RKHVGS-nad",
+    "lunzer-RKHVGS-nadp",
+    "lunzer-RKHVYR-nad",
+    "lunzer-RKHVYR-nadp",
+    "lunzer-RKHVYS-nad",
+    "lunzer-RKHVYS-nadp",
+    "lunzer-RKIAGR-nad",
+    "lunzer-RKIAGR-nadp",
+    "lunzer-RKIAGS-nad",
+    "lunzer-RKIAGS-nadp",
+    "lunzer-RKIAYR-nad",
+    "lunzer-RKIAYR-nadp",
+    "lunzer-RKIAYS-nad",
+    "lunzer-RKIAYS-nadp",
+    "lunzer-RKIVGR-nad",
+    "lunzer-RKIVGR-nadp",
+    "lunzer-RKIVGS-nad",
+    "lunzer-RKIVGS-nadp",
+    "lunzer-RKIVYR-nad",
+    "lunzer-RKIVYR-nadp",
+    "lunzer-RKIVYS-nad",
+    "lunzer-RKIVYS-nadp",
+    "lunzer-RKKAGR-nad",
+    "lunzer-RKKAGR-nadp",
+    "lunzer-RKKAGS-nad",
+    "lunzer-RKKAGS-nadp",
+    "lunzer-RKKAYR-nad",
+    "lunzer-RKKAYR-nadp",
+    "lunzer-RKKAYS-nad",
+    "lunzer-RKKAYS-nadp",
+    "lunzer-RKKVGR-nad",
+    "lunzer-RKKVGR-nadp",
+    "lunzer-RKKVGS-nad",
+    "lunzer-RKKVGS-nadp",
+    "lunzer-RKKVYR-nad",
+    "lunzer-RKKVYR-nadp",
+    "lunzer-RKKVYS-nad",
+    "lunzer-RKKVYS-nadp",
+    "lunzer-RKLAGR-nad",
+    "lunzer-RKLAGR-nadp",
+    "lunzer-RKLAGS-nad",
+    "lunzer-RKLAGS-nadp",
+    "lunzer-RKLAYR-nad",
+    "lunzer-RKLAYR-nadp",
+    "lunzer-RKLAYS-nad",
+    "lunzer-RKLAYS-nadp",
+    "lunzer-RKLVGR-nad",
+    "lunzer-RKLVGR-nadp",
+    "lunzer-RKLVGS-nad",
+    "lunzer-RKLVGS-nadp",
+    "lunzer-RKLVYR-nad",
+    "lunzer-RKLVYR-nadp",
+    "lunzer-RKLVYS-nad",
+    "lunzer-RKLVYS-nadp",
+    "lunzer-RKNAGR-nad",
+    "lunzer-RKNAGR-nadp",
+    "lunzer-RKNAGS-nad",
+    "lunzer-RKNAGS-nadp",
+    "lunzer-RKNAYR-nad",
+    "lunzer-RKNAYR-nadp",
+    "lunzer-RKNAYS-nad",
+    "lunzer-RKNAYS-nadp",
+    "lunzer-RKNVGR-nad",
+    "lunzer-RKNVGR-nadp",
+    "lunzer-RKNVGS-nad",
+    "lunzer-RKNVGS-nadp",
+    "lunzer-RKNVYR-nad",
+    "lunzer-RKNVYR-nadp",
+    "lunzer-RKNVYS-nad",
+    "lunzer-RKNVYS-nadp",
+    "lunzer-RKQAGR-nad",
+    "lunzer-RKQAGR-nadp",
+    "lunzer-RKQAGS-nad",
+    "lunzer-RKQAGS-nadp",
+    "lunzer-RKQAYR-nad",
+    "lunzer-RKQAYR-nadp",
+    "lunzer-RKQAYS-nad",
+    "lunzer-RKQAYS-nadp",
+    "lunzer-RKQVGR-nad",
+    "lunzer-RKQVGR-nadp",
+    "lunzer-RKQVGS-nad",
+    "lunzer-RKQVGS-nadp",
+    "lunzer-RKQVYR-nad",
+    "lunzer-RKQVYR-nadp",
+    "lunzer-RKQVYS-nad",
+    "lunzer-RKQVYS-nadp",
+    "lunzer-RKYAGR-nad",
+    "lunzer-RKYAGR-nadp",
+    "lunzer-RKYAGS-nad",
+    "lunzer-RKYAGS-nadp",
+    "lunzer-RKYAYR-nad",
+    "lunzer-RKYAYR-nadp",
+    "lunzer-RKYAYS-nad",
+    "lunzer-RKYAYS-nadp",
+    "lunzer-RKYVGR-nad",
+    "lunzer-RKYVGR-nadp",
+    "lunzer-RKYVGS-nad",
+    "lunzer-RKYVGS-nadp",
+    "lunzer-RKYVYR-nad",
+    "lunzer-RKYVYR-nadp",
+    "lunzer-RKYVYS-nad",
+    "lunzer-RKYVYS-nadp",
+    "lunzer-RNFAGR-nad",
+    "lunzer-RNFAGR-nadp",
+    "lunzer-RNFAGS-nad",
+    "lunzer-RNFAGS-nadp",
+    "lunzer-RNFAYR-nad",
+    "lunzer-RNFAYR-nadp",
+    "lunzer-RNFAYS-nad",
+    "lunzer-RNFAYS-nadp",
+    "lunzer-RNFVGR-nad",
+    "lunzer-RNFVGR-nadp",
+    "lunzer-RNFVGS-nad",
+    "lunzer-RNFVGS-nadp",
+    "lunzer-RNFVYR-nad",
+    "lunzer-RNFVYR-nadp",
+    "lunzer-RNFVYS-nad",
+    "lunzer-RNFVYS-nadp",
+    "lunzer-RNHAGR-nad",
+    "lunzer-RNHAGR-nadp",
+    "lunzer-RNHAGS-nad",
+    "lunzer-RNHAGS-nadp",
+    "lunzer-RNHAYR-nad",
+    "lunzer-RNHAYR-nadp",
+    "lunzer-RNHAYS-nad",
+    "lunzer-RNHAYS-nadp",
+    "lunzer-RNHVGR-nad",
+    "lunzer-RNHVGR-nadp",
+    "lunzer-RNHVGS-nad",
+    "lunzer-RNHVGS-nadp",
+    "lunzer-RNHVYR-nad",
+    "lunzer-RNHVYR-nadp",
+    "lunzer-RNHVYS-nad",
+    "lunzer-RNHVYS-nadp",
+    "lunzer-RNIAGR-nad",
+    "lunzer-RNIAGR-nadp",
+    "lunzer-RNIAGS-nad",
+    "lunzer-RNIAGS-nadp",
+    "lunzer-RNIAYR-nad",
+    "lunzer-RNIAYR-nadp",
+    "lunzer-RNIAYS-nad",
+    "lunzer-RNIAYS-nadp",
+    "lunzer-RNIVGR-nad",
+    "lunzer-RNIVGR-nadp",
+    "lunzer-RNIVGS-nad",
+    "lunzer-RNIVGS-nadp",
+    "lunzer-RNIVYR-nad",
+    "lunzer-RNIVYR-nadp",
+    "lunzer-RNIVYS-nad",
+    "lunzer-RNIVYS-nadp",
+    "lunzer-RNKAGR-nad",
+    "lunzer-RNKAGR-nadp",
+    "lunzer-RNKAGS-nad",
+    "lunzer-RNKAGS-nadp",
+    "lunzer-RNKAYR-nad",
+    "lunzer-RNKAYR-nadp",
+    "lunzer-RNKAYS-nad",
+    "lunzer-RNKAYS-nadp",
+    "lunzer-RNKVGR-nad",
+    "lunzer-RNKVGR-nadp",
+    "lunzer-RNKVGS-nad",
+    "lunzer-RNKVGS-nadp",
+    "lunzer-RNKVYR-nad",
+    "lunzer-RNKVYR-nadp",
+    "lunzer-RNKVYS-nad",
+    "lunzer-RNKVYS-nadp",
+    "lunzer-RNLAGR-nad",
+    "lunzer-RNLAGR-nadp",
+    "lunzer-RNLAGS-nad",
+    "lunzer-RNLAGS-nadp",
+    "lunzer-RNLAYR-nad",
+    "lunzer-RNLAYR-nadp",
+    "lunzer-RNLAYS-nad",
+    "lunzer-RNLAYS-nadp",
+    "lunzer-RNLVGR-nad",
+    "lunzer-RNLVGR-nadp",
+    "lunzer-RNLVGS-nad",
+    "lunzer-RNLVGS-nadp",
+    "lunzer-RNLVYR-nad",
+    "lunzer-RNLVYR-nadp",
+    "lunzer-RNLVYS-nad",
+    "lunzer-RNLVYS-nadp",
+    "lunzer-RNNAGR-nad",
+    "lunzer-RNNAGR-nadp",
+    "lunzer-RNNAGS-nad",
+    "lunzer-RNNAGS-nadp",
+    "lunzer-RNNAYR-nad",
+    "lunzer-RNNAYR-nadp",
+    "lunzer-RNNAYS-nad",
+    "lunzer-RNNAYS-nadp",
+    "lunzer-RNNVGR-nad",
+    "lunzer-RNNVGR-nadp",
+    "lunzer-RNNVGS-nad",
+    "lunzer-RNNVGS-nadp",
+    "lunzer-RNNVYR-nad",
+    "lunzer-RNNVYR-nadp",
+    "lunzer-RNNVYS-nad",
+    "lunzer-RNNVYS-nadp",
+    "lunzer-RNQAGR-nad",
+    "lunzer-RNQAGR-nadp",
+    "lunzer-RNQAGS-nad",
+    "lunzer-RNQAGS-nadp",
+    "lunzer-RNQAYR-nad",
+    "lunzer-RNQAYR-nadp",
+    "lunzer-RNQAYS-nad",
+    "lunzer-RNQAYS-nadp",
+    "lunzer-RNQVGR-nad",
+    "lunzer-RNQVGR-nadp",
+    "lunzer-RNQVGS-nad",
+    "lunzer-RNQVGS-nadp",
+    "lunzer-RNQVYR-nad",
+    "lunzer-RNQVYR-nadp",
+    "lunzer-RNQVYS-nad",
+    "lunzer-RNQVYS-nadp",
+    "lunzer-RNYAGR-nad",
+    "lunzer-RNYAGR-nadp",
+    "lunzer-RNYAGS-nad",
+    "lunzer-RNYAGS-nadp",
+    "lunzer-RNYAYR-nad",
+    "lunzer-RNYAYR-nadp",
+    "lunzer-RNYAYS-nad",
+    "lunzer-RNYAYS-nadp",
+    "lunzer-RNYVGR-nad",
+    "lunzer-RNYVGR-nadp",
+    "lunzer-RNYVGS-nad",
+    "lunzer-RNYVGS-nadp",
+    "lunzer-RNYVYR-nad",
+    "lunzer-RNYVYR-nadp",
+    "lunzer-RNYVYS-nad",
+    "lunzer-RNYVYS-nadp"
+  ],
+  "cofactor_counts": {
+    "NAD": 512,
+    "NADP": 512
+  },
+  "dataset": "Lunzer ancient adaptive landscape",
+  "dataset_doi": "10.5061/dryad.7nd70",
+  "frozen_protocol": {
+    "endpoint": "derived_ln_kcat_equals_ln_km_plus_ln_kcat_over_km",
+    "primary_metrics": [
+      "within_cofactor_spearman",
+      "within_cofactor_pairwise_accuracy",
+      "within_cofactor_top_10pct_enrichment"
+    ],
+    "random_expectations": {
+      "pairwise_accuracy": 0.5,
+      "spearman": 0.0,
+      "top_10pct_enrichment": 1.0
+    },
+    "status": "confirmatory_no_model_selection"
+  },
+  "genotypes": 512,
+  "license": "CC0-1.0",
+  "limitations": [
+    "All variants share one E. coli IMDH scaffold; this is not homology-cold.",
+    "The deposited values are model-fit kinetics rather than independent raw replicates.",
+    "An unresolved source-unit constant prevents absolute RMSE claims; ranking is invariant.",
+    "The UniKP corpus lacks record-level citations, so publication overlap is unavailable."
+  ],
+  "records": 1024,
+  "source_identity": {
+    "row_count": 513,
+    "sha256": "7bfd71d78235ade06a9e117b8229ad99b1fe7adceb0a5ed72d708c3e925c2a69",
+    "size_bytes": 38761
+  },
+  "unikp_exact_overlap": {
+    "exact_sequence_records": 0,
+    "exact_sequence_substrate_pairs": 0,
+    "exact_substrate_records": 0,
+    "publication_overlap": "unavailable_no_record_level_unikp_citations"
+  }
+}

data/temporal/global-accepted-mapping.csv

@@ -0,0 +1,204 @@
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data/temporal/readiness-audit.json

@@ -0,0 +1,234 @@
+{
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+    "global_fasta_sha256": "0e631ed695ec3bd9fcd17fc3b91b67cc26b21a5980eb5377bfce40e53f42695b",
+    "mapping_manifest": "artifacts\\external\\temporal-global-family-audit\\global-accepted-mapping.csv",
+    "mapping_manifest_sha256": "54226ec20c18f296b789d20fa52642174317dfbd93492428ad3b9ae3aefedf48"
+  },
+  "blockers": [
+    "capped records 192 < required 300",
+    "global families 25 < required 30"
+  ],
+  "claim_boundary": "Readiness audit only; no model predictions or scores were generated.",
+  "counts": {
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+    "excluded_or_unresolved_sources": 0,
+    "global_families": 25,
+    "mapped_component_sequences": 203,
+    "mapped_records_before_cap": 192,
+    "records_after_global_family_cap": 192,
+    "substrates_after_global_family_cap": 54
+  },
+  "family_record_counts_before_cap": {
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+    "family-0025": 7
+  },
+  "generated_on": "2026-07-27",
+  "mmseqs": {
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+    "cluster_tsv_sha256": "74fff00b5c9d75022d4826cefe5ed918b81f6187bda288e4b3716ea98c1218db",
+    "executable": "wsl:Ubuntu-24.04:<redacted-local-path>",
+    "observed_version": "5d152c612b6ad2a56f657b7a02c127eceaea2a75",
+    "required_version": "5d152c612b6ad2a56f657b7a02c127eceaea2a75"
+  },
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+    "maximum_records_per_family": 20,
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+    "multicomponent_rule": "records are connected when any components share a global MMseqs cluster"
+  },
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+}

data/temporal/registry-readiness-audit.json

@@ -0,0 +1,526 @@
+{
+  "schema_version": 2,
+  "generated_on": "2026-07-27",
+  "root": "artifacts/external/temporal-absolute-kinetics",
+  "protocol": "configs/temporal_absolute_kinetics_protocol.json",
+  "protocol_sha256": "a9ebdc022d77925ebdf32abd016e4ab09fae6a1ab4421dde7bb675107742e36f",
+  "accepted_status": "accepted_homology_cold_pool",
+  "substrate_identity_policy": "PubChem CID of the varied, measured substrate",
+  "family_policy": "none",
+  "family_policy_note": "not reported; select an explicit family policy",
+  "registry_readiness_policy": {
+    "finalized_zero_candidate_sources_must_pass_evidence_checks": false
+  },
+  "source_summary": {
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+    "pending_sources": 0,
+    "finalized_zero_candidate_sources": 28,
+    "unresolved_zero_candidate_sources": 0,
+    "nonblocking_source_issues": 21
+  },
+  "counts": {
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+    "globally_unique_substrates": 54,
+    "families": null
+  },
+  "readiness_gate_passes": false,
+  "blockers": [
+    "accepted records 192 < required 300",
+    "global family readiness gate cannot be evaluated"
+  ],
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+    "seed": 42,
+    "selected_kind": "identity",
+    "tie_rule": "nll_then_crps_then_simpler_model_within_tolerances"
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+  "validation_count": 1640
+}

data/unikp-km-training-blocker-audit.json

@@ -0,0 +1,295 @@
+{
+  "schema_version": "1.0.0",
+  "audit_date": "2026-07-27",
+  "task": "BioCandidateRanker absolute Km training from local UniKP assets",
+  "status": "blocked",
+  "decision": {
+    "training_performed": false,
+    "adapter_written": false,
+    "normalized_jsonl_written": false,
+    "split_written": false,
+    "checkpoint_written": false,
+    "external_benchmark_scoring_performed": false,
+    "reason_code": "OPAQUE_TEST_PICKLE_WITH_UNRESOLVED_ROW_PROVENANCE_UNITS_LICENSE_AND_SPLIT",
+    "summary": "The only local UniKP Km labels are in an upstream test-named pandas pickle. The object has usable sequences, SMILES, and finite log10_KM values, but lacks row-level measurement provenance, source units, assay metadata, direct-measurement flags, and frozen split membership. Conflicting license signals and the inability to connect each transformed row to a governed source measurement prevent conversion to BioCandidateRanker's strict direct-kinetics schema.",
+    "claim_boundary": "No model prediction was used as a label. The pretrained UniKP Km model is an inference artifact and was excluded as a label source. No Km training or evaluation was run."
+  },
+  "search_scope": {
+    "roots": [
+      "<redacted-local-path>",
+      "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP",
+      "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment - \u526f\u672c",
+      "<redacted-local-path> model prediction\\Yeast-MetaTwin",
+      "<redacted-local-path> model prediction\\Yeast-MetaTwin\\_backup_opencode_20260707_compat_fixes",
+      "<redacted-local-path> model prediction\\Yeast-MetaTwin\\_backup_opencode_20260707_eval_fixes",
+      "<redacted-local-path>"
+    ],
+    "name_and_content_terms": [
+      "UniKP",
+      "unikp",
+      "Km_test_11722",
+      "log10_KM",
+      "UniKP for Km",
+      "Km_features_11722",
+      "kcat_km_samples"
+    ],
+    "result": "One local Km label object was found. Other references resolve to the same deployed object, missing expected source assets, code copies, pretrained models, or prediction outputs."
+  },
+  "label_asset": {
+    "path": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP\\datasets\\Km_test_11722.pkl",
+    "exists": true,
+    "format": "Python pickle containing pandas.core.frame.DataFrame",
+    "pickle_security": "opaque executable serialization; inspected only in the existing isolated UniKP environment after identity hashing",
+    "size_bytes": 3295007,
+    "sha256": "10f565a6b369e374d15c872ce732630de80a06e89dac17256e62b1dfaa75a790",
+    "git_blob_sha1": "e668ff16a59f8143ce5f9aa972fae2894280e8a4",
+    "exact_upstream_blob_match": true,
+    "upstream_blob_url": "https://github.com/Luo-SynBioLab/UniKP/blob/3ad5576aaa2c8c0dd0e0b6c283c1d365ab23c6ea/datasets/Km_test_11722.pkl",
+    "object_shape": [
+      11722,
+      4
+    ],
+    "columns": [
+      {
+        "name": "KEGG ID",
+        "semantic": "substrate KEGG compound identifier",
+        "dtype": "object",
+        "non_null": 11722,
+        "unique": 1580,
+        "minimum_string_length": 6,
+        "maximum_string_length": 6
+      },
+      {
+        "name": "Sequence",
+        "semantic": "amino-acid sequence used as a model input",
+        "dtype": "object",
+        "non_null": 11722,
+        "unique": 6990,
+        "minimum_length": 5,
+        "maximum_length": 7096,
+        "rows_with_characters_outside_ACDEFGHIKLMNPQRSTVWYBXZOUJ": 0
+      },
+      {
+        "name": "smiles",
+        "semantic": "substrate structure used as a model input",
+        "dtype": "object",
+        "non_null": 11722,
+        "unique": 1566,
+        "minimum_length": 1,
+        "maximum_length": 318,
+        "rdkit_parse_failures": 0,
+        "rdkit_canonical_unique": 1566,
+        "multi_component_rows": 1,
+        "rdkit_version": "2026.03.4"
+      },
+      {
+        "name": "log10_KM",
+        "semantic": "transformed Km label; physical source unit is not stored",
+        "dtype": "float64",
+        "non_null": 11722,
+        "finite": 11722,
+        "unique": 5224,
+        "minimum": -4.982966660701219,
+        "maximum": 3.929418925714293,
+        "mean": -0.7687990643747526
+      }
+    ],
+    "absent_fields": [
+      "BRENDA accession or source row identifier",
+      "SABIO-RK accession",
+      "publication DOI or citation per measurement",
+      "experimental versus predicted label flag",
+      "original linear Km value",
+      "original and transformed Km unit",
+      "assay pH",
+      "assay temperature",
+      "buffer and other assay conditions",
+      "organism",
+      "EC number",
+      "protein accession",
+      "replicate or geometric-aggregation membership",
+      "train, validation, or test membership"
+    ]
+  },
+  "data_quality_and_leakage_audit": {
+    "exact_duplicate_rows": 0,
+    "duplicate_sequence_smiles_rows": 24,
+    "sequence_smiles_pairs_with_conflicting_labels": 20,
+    "rows_repeating_a_sequence": 4732,
+    "sequences_with_multiple_labels": 3094,
+    "ordered_sequence_smiles_pair_sha256": "857c15b5a495a06b2ea48b3a9496c1b25c30b4324444e7b60561ba01b2752c53",
+    "split_semantics": {
+      "local_assignments_present": false,
+      "upstream_unikp_code": "Loads all 11,722 rows, chooses an unrecorded random seed with random.randint(0, 1000), then calls train_test_split(test_size=0.2).",
+      "upstream_unikp_paper": "Describes a random 80/20 training/test division of the 11,722 combinations.",
+      "source_kroll_paper": "Describes 11,675 complete BRENDA entries, geometric aggregation for repeated sequence-substrate measurements, a frozen 80/20 BRENDA split, and a separate 274-row SABIO-RK test.",
+      "conclusion": "The filename 'test' does not identify a protected local holdout. The local object is used as a full development corpus by UniKP code, and its rows cannot be mapped back to the Kroll train/test assignments. A random row split would allow repeated sequences and possibly repeated input pairs across partitions and is not leakage-aware."
+    },
+    "minimum_acceptable_future_split": "Resolve row identities and units first, aggregate or adjudicate conflicting sequence-SMILES labels without test access, reserve any original frozen tests, and assign sequence-homology clusters wholly to train, validation, or test."
+  },
+  "provenance": {
+    "immediate_source": {
+      "project": "Luo-SynBioLab/UniKP",
+      "repository": "https://github.com/Luo-SynBioLab/UniKP",
+      "audited_commit": "3ad5576aaa2c8c0dd0e0b6c283c1d365ab23c6ea",
+      "commit_date": "2025-12-30T04:43:18Z",
+      "paper_doi": "10.1038/s41467-023-44113-1",
+      "paper_statement": "The Km task uses a reported representative dataset from Kroll et al. with 11,722 natural enzyme-substrate combinations and corresponding Km values.",
+      "code_identity": {
+        "local_path": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP\\code\\UniKP_Km.py",
+        "size_bytes": 5305,
+        "sha256": "6a960f95fac50c2b194fd8dceaf50e1f7929e90fa5df84ef166607150514fc2e",
+        "git_blob_sha1": "6cf407268e03e6a8998d2d222c04d0699caae584",
+        "exact_upstream_blob_match": true
+      }
+    },
+    "reported_ultimate_source": {
+      "project": "AlexanderKroll/KM_prediction",
+      "repository": "https://github.com/AlexanderKroll/KM_prediction",
+      "paper_doi": "10.1371/journal.pbio.3001402",
+      "paper_statement": "Wild-type BRENDA measurements were joined to organism, EC, UniProt sequence, and substrate structure; repeated values for the same sequence-substrate combination were geometrically averaged and log10 transformed.",
+      "paper_row_count": 11675,
+      "local_unikp_row_count": 11722,
+      "row_count_reconciliation": "unresolved",
+      "paper_unit_evidence": "The Kroll article discusses Km values on a log10 scale and reports ranges in mM, but the local pickle itself does not bind log10_KM to a physical unit.",
+      "row_level_lineage_preserved_locally": false
+    },
+    "provenance_grade": "corpus-level attribution only; insufficient for strict direct-label conversion"
+  },
+  "license_audit": {
+    "unikp_github_commit": {
+      "license_file_present": false,
+      "readme_claim": "GNU General Public License version 3",
+      "status": "ambiguous because the commit tree has no license text and a README link alone does not resolve third-party dataset rights"
+    },
+    "unikp_zenodo_record": {
+      "doi": "10.5281/zenodo.10115498",
+      "record_type": "software",
+      "metadata_license": "CC BY 4.0",
+      "status": "conflicts with the GitHub README GPL-3.0 claim and does not provide row-level third-party source rights in the local pickle"
+    },
+    "kroll_repository": {
+      "repository": "https://github.com/AlexanderKroll/KM_prediction",
+      "detected_license": "MIT",
+      "license_file": "LICENSE.md",
+      "status": "governs the deposited software/materials but cannot by itself grant rights the authors did not hold in underlying BRENDA records"
+    },
+    "articles": {
+      "unikp_article": "CC BY 4.0",
+      "kroll_article": "CC BY 4.0",
+      "status": "article licenses do not automatically establish redistribution and derivative-training rights for database records"
+    },
+    "underlying_database": {
+      "name": "BRENDA",
+      "license_or_terms_captured_per_row": false,
+      "status": "unresolved in the local asset"
+    },
+    "legal_conclusion": "Training authorization and redistribution status are not sufficiently established for this transformed local pickle. This is an engineering governance conclusion, not legal advice."
+  },
+  "model_and_nonlabel_assets": [
+    {
+      "path": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP\\models\\UniKP for Km.pkl",
+      "type": "pretrained sklearn ExtraTreesRegressor",
+      "size_bytes": 147957236,
+      "sha256": "f0b8d597cf4e5f73431980950cb89423415a260dbbf9be0bb1d8810712bf9c07",
+      "label_eligible": false,
+      "reason": "Model outputs are predictions, not experimental labels."
+    },
+    {
+      "path": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP\\models\\trfm_12_23000.pkl",
+      "type": "SMILES representation weights",
+      "label_eligible": false
+    },
+    {
+      "path": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP\\models\\prot_t5_xl_uniref50",
+      "type": "protein representation model",
+      "label_eligible": false
+    },
+    {
+      "paths": [
+        "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\06_evaluation\\10h2da_unikp_terminal_predictions.csv",
+        "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\06_evaluation\\10h2da_external_omega_hydroxylase_unikp_predictions.csv"
+      ],
+      "type": "UniKP prediction outputs",
+      "label_eligible": false,
+      "reason": "Predictions must not be promoted to labels."
+    }
+  ],
+  "missing_or_reference_only_assets": [
+    {
+      "path": "<redacted-local-path> model prediction\\Yeast-MetaTwin\\Code\\kcatkm_prediction\\UniKP\\Km\\Km_test_11722.pkl",
+      "status": "missing; referenced by copied code and prior inventory only"
+    },
+    {
+      "path": "<redacted-local-path> model prediction\\Yeast-MetaTwin\\Code\\kcatkm_prediction\\UniKP\\Km\\Km_features_11722_PreKcat.pkl",
+      "status": "missing; would be derived model features, not raw labels"
+    },
+    {
+      "path": "<redacted-local-path> model prediction\\Yeast-MetaTwin\\Code\\kcatkm_prediction\\UniKP\\Kcat_Km\\kcat_km_samples.xlsx",
+      "status": "missing and targets kcat/Km rather than Km"
+    },
+    {
+      "path": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment - \u526f\u672c\\04_prediction_plugins\\UniKP",
+      "status": "missing; the copy contains only a Python environment and top-level documentation"
+    }
+  ],
+  "blocking_findings": [
+    {
+      "code": "ROW_PROVENANCE_MISSING",
+      "severity": "fatal",
+      "detail": "No local row can be traced to a BRENDA/SABIO record, source publication, or assay."
+    },
+    {
+      "code": "DIRECT_EVIDENCE_NOT_ROW_VERIFIABLE",
+      "severity": "fatal",
+      "detail": "The papers describe experimental source data at corpus level, but the transformed pickle has no per-row direct-measurement evidence."
+    },
+    {
+      "code": "PHYSICAL_UNIT_NOT_STORED",
+      "severity": "fatal",
+      "detail": "log10_KM cannot be converted to strict log10(M) from the object alone without assuming an upstream source unit."
+    },
+    {
+      "code": "ROW_COUNT_LINEAGE_UNRESOLVED",
+      "severity": "fatal",
+      "detail": "The local/UniKP count of 11,722 does not match the 11,675 complete BRENDA entries described by the cited Kroll paper, and no transformation manifest reconciles them."
+    },
+    {
+      "code": "LICENSE_CHAIN_UNRESOLVED",
+      "severity": "fatal",
+      "detail": "UniKP GitHub README GPL-3.0, UniKP Zenodo CC BY 4.0, Kroll MIT, article CC BY 4.0, and underlying BRENDA rights are not reconciled for the transformed rows."
+    },
+    {
+      "code": "SPLIT_MEMBERSHIP_MISSING",
+      "severity": "fatal",
+      "detail": "The test-named pickle contains no frozen split and upstream UniKP code randomly repartitions all rows."
+    },
+    {
+      "code": "INPUT_PAIR_CONFLICTS",
+      "severity": "fatal",
+      "detail": "Twenty sequence-SMILES pairs carry multiple label values, with no replicate provenance or adjudication rule."
+    },
+    {
+      "code": "HOMOLOGY_LEAKAGE_NOT_CONTROLLED",
+      "severity": "fatal",
+      "detail": "No homology-cluster assignment exists; random row splitting is not suitable for leakage-aware BioCandidateRanker training."
+    }
+  ],
+  "conditions_to_unblock": [
+    "Acquire a non-pickle governed source table with stable row identifiers and an explicit license/terms snapshot covering the records and intended training use.",
+    "Provide per-row original linear Km values, physical units, direct experimental citations/accessions, exact protein sequences, substrate structures, and aggregation lineage.",
+    "Reconcile the 11,722 versus 11,675 row counts and document all UniKP transformations.",
+    "Recover and preserve original frozen test membership; do not merge protected tests into development data.",
+    "Resolve conflicting sequence-SMILES measurements using a prespecified, provenance-preserving policy.",
+    "Build a label-independent protein-homology-cluster split and audit exact sequence-SMILES overlap across partitions.",
+    "Only after all gates pass, convert direct measurements to schema v1 log10(M), validate through read_normalized_kinetics_jsonl, and run a training-only smoke without external benchmark scoring."
+  ],
+  "sources_consulted": [
+    "https://github.com/Luo-SynBioLab/UniKP/tree/3ad5576aaa2c8c0dd0e0b6c283c1d365ab23c6ea",
+    "https://github.com/Luo-SynBioLab/UniKP/blob/3ad5576aaa2c8c0dd0e0b6c283c1d365ab23c6ea/UniKP_Km.py",
+    "https://doi.org/10.1038/s41467-023-44113-1",
+    "https://doi.org/10.5281/zenodo.10115498",
+    "https://github.com/AlexanderKroll/KM_prediction",
+    "https://doi.org/10.1371/journal.pbio.3001402"
+  ]
+}

data/unikp_audit.json

@@ -0,0 +1,20 @@
+{
+  "adapter": {
+    "accepted_rows": 16838,
+    "conflicting_duplicate_rows": 215,
+    "duplicate_rows": 395,
+    "rejected_rows": 172,
+    "total_rows": 17010
+  },
+  "identity": {
+    "row_count": 17010,
+    "sha256": "13643b0b36374f8d3f64d8b014882cf1b3b58946eeaae2b9dcd59e8b2c2d6719",
+    "size_bytes": 12132719
+  },
+  "limitations": [
+    "Source rows lack record-level accession provenance.",
+    "No frozen independent benchmark is bundled.",
+    "Exact protein-cold split is not a homology-cold split."
+  ],
+  "source": "<redacted-local-path> model prediction\\Integrated_Yeast_MetaTwin_Deployment\\04_prediction_plugins\\UniKP\\datasets\\Kcat_combination_0918_wildtype_mutant.json"
+}

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