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smiles,score
Cc1[nH]c2ccc(C(=O)Nc3cc(C(C)(C)C)nn3-c3ncccn3)cc2c1C,0.7285714285714285
Cc1c(C(=O)N2CCOCC2)oc2c1-c1nn(CC(=O)NCc3ccco3)cc1CC2,0.7214285714285714
Cc1nn(-c2nncc(-c3ccc(Cl)cc3)n2)c2c1[C@H](c1ccccc1)CC(=O)N2,0.7214285714285714
O=C1/C(=C/c2ccccc2)Oc2c1ccc1c2CN(Cc2cccs2)CO1,0.7214285714285714
CCOC(=O)[C@@H]1CCCN(C(=O)c2nc(-c3ccc(C)cc3)n3c2CCCCC3)C1,0.7142857142857143
O=[N+]([O-])c1c(Nc2cccc3ncccc23)ncnc1N1CCN(c2cccc(Cl)c2)CC1,0.7142857142857143
O=C(CSc1nnc(-c2cccc([N+](=O)[O-])c2)o1)Nc1nncs1,0.7142857142857143
Cc1cc(NC(=O)CSc2nnc3c4ccccc4n(C)c3n2)ccc1Br,0.7142857142857143
Cc1ccc(S(=O)(=O)N2CCN(C(=O)[C@H]3CCCC[C@@H]3C(=O)[O-])CC2)cc1C,0.7142857142857143
Cc1c(/C=N/c2cc(Br)ccn2)c(O)n2c(nc3ccccc32)c1C#N,0.7071428571428572
O=C1c2ccccc2N[C@H](CSC2=NC=NC3=NC=N[C@@H]32)N1c1ccc(Cl)cc1,0.7071428571428572
CC(=O)Nc1nc2ccc(NC(=O)NCc3ccccc3)cc2s1,0.7071428571428572
Cc1ccc(-c2cc(NC(=O)C(C)C)c(=O)n(CC(=O)Nc3cccc(C)c3)n2)cc1,0.7071428571428572
Cc1cc(-n2c(C)cc(C[NH2+][C@H](C)c3ccc(F)c(F)c3)c2C)no1,0.7000000000000001
C[C@H](OC(=O)c1nc(C2CC2)n2ccccc12)c1cnc2ccccc2c1,0.7000000000000001
Cc1cccc(NC(=O)CN2CCN(c3ccc4c(c3)OCCO4)C2=O)n1,0.7000000000000001
Cc1ccc(N2CC[C@@H](NS(=O)(=O)c3ccccc3C)C2=O)cc1C,0.6928571428571428
NC(=O)CCOc1ccc(NC(=O)C[C@H]2CCc3ccccc32)cc1,0.6928571428571428
COc1ccc(NC(=O)N2CCN(C(=O)Cc3csc4ccccc34)CC2)cc1OC,0.6928571428571428
O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1cc(Cl)c(Cl)cc1Cl,0.6928571428571428
O=C(c1cc2cc([N+](=O)[O-])ccc2oc1=O)N1CCN(Cc2ccccc2)CC1,0.6857142857142857
COc1cccc(CN2CCc3nnc(CCc4ccccc4)n3CC2)c1,0.6857142857142857
CCc1c(C(=O)Nc2ccc3c(c2)NC(=O)CS3)[nH]c(C)c1C(C)=O,0.6857142857142857
CC(C)(C)c1ccc2occ(CC(=O)Nc3ccccc3F)c2c1,0.6785714285714286
Cc1nc2c(c(Nc3ncc(C)s3)n1)CCN(C(=O)CCc1ccccc1)C2,0.6785714285714286
Cc1ccc(-c2nnc(C[NH+](CCO)[C@H]3CCc4ccccc43)o2)cc1,0.6785714285714286
CC[C@@H](NC(=O)N(C)Cc1ccc(-c2ccccc2)cc1)c1ccncc1,0.6785714285714286
C=C(C)C(=O)N[C@H](C)c1nc2ccccc2n1CCC(=O)N1CCCCCC1,0.6785714285714286
O=C(N1CCc2c(F)ccc(F)c2C1)C1(O)Cc2ccccc2C1,0.6714285714285715
COc1ccc(C)cc1-n1nnnc1SCC(=O)Nc1cc(C)cc(C)c1,0.6714285714285715
O=C(Nc1nc[nH]n1)c1cccnc1Nc1cccc(F)c1,0.6642857142857144
CCn1cc(S(=O)(=O)N2CCCCC[C@@H]2c2cc(-c3ccc(F)cc3)no2)cn1,0.6642857142857144
COc1cccc(-c2cncc3ccccc23)c1C(=O)N(C(C)C)C(C)C,0.6642857142857144
CCc1ccc(NC(=O)c2nn(-c3ccc(CC)cc3)ccc2=O)cc1,0.6642857142857144
CC(C)(C)n1ncc2c1CCC[C@H]2NC(=O)CSc1nc2ccccc2o1,0.6642857142857144
Cc1cccc(C(=O)N[C@@H](C(=O)N2CCC[C@@H](C)C2)C(C)C)c1,0.6642857142857144
C[C@@H]1CC[C@@H]([NH2+]C2CCC(NS(C)(=O)=O)CC2)c2ccccc21,0.6642857142857144
Cc1ccc2nc(S[C@H](C)C(=O)NC3CCC(C)CC3)n(C)c(=O)c2c1,0.6571428571428571
O=C1C[C@H](c2nc(-c3cccnc3)no2)CN1c1cccc(Cl)c1,0.6571428571428571
Cc1ccc2ncc(C(=O)Nc3ncccc3OCc3ccncc3)n2c1,0.6571428571428571
CCc1nc2ccccc2c(C(=O)NCc2ccc(OC)c(C(=O)OC)c2)c1C,0.65
Cc1[nH]c(=O)c(C(=O)N2CCN(c3ccccc3)C(=O)C2)c(C)c1C,0.65
Cc1cc(N(C)C)ccc1NC(=O)c1c[nH]c2nccc(Cl)c12,0.65
CC(C)c1noc(-c2cc[nH+]c(N3CCN(C(=O)[C@H]4C[C@H]4C)CC3)c2)n1,0.65
O=C(NCc1nccc2ccccc12)c1ccc[nH]c1=O,0.6428571428571429
COc1ccc([C@H]2C[C@@H](C(F)(F)F)n3nc(C(=O)NC4CCCCC4)cc3N2)cc1OC,0.6428571428571429
O=C(C=C1CCSCC1)N[C@@H]1CCC[C@H]1Cc1ccccc1,0.6428571428571429
CC[C@@H](C)[C@@H](NC(=O)c1cccc(F)c1)C(=O)N=c1[nH]c2ccccc2[nH]1,0.6428571428571429
CC(C)Cc1nc(SCC(=O)NC[C@@H]2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1,0.6357142857142858
O=C(NCCNC(=O)N1C[C@H]2CC=CC[C@@H]2C1)c1cccnc1,0.6357142857142858
C=CCn1c(S[C@H](C)C(=O)N2CCC(C)CC2)nnc1-c1ccc(Cl)cc1,0.6357142857142858
Cc1cnc(C(=O)Nc2ccc(N(C)C3CC[NH+](C)CC3)cc2)cn1,0.6357142857142858
Cc1ccc([N+](=O)[O-])cc1NC(=O)C(=O)N1CC[C@H]([NH+]2CCCC2)C1,0.6357142857142858
O=C(NCCS(=O)(=O)c1ccccc1)N1CCC[C@@H]2CCC[C@@H]21,0.6357142857142858
CCOc1ccc(OCC)c([C@H]2C(C#N)=C(N)N(c3ccccc3C(F)(F)F)C3=C2C(=O)CCC3)c1,0.6285714285714287
N#Cc1ccncc1NC[C@@H]1C[C@@]12CCc1ccccc12,0.6285714285714287
CNC(=O)c1ccc(/C=C/C(=O)Nc2c(C)cc(C)nc2Cl)cc1,0.6285714285714287
COc1ccccc1NC(=O)CSc1ccc(-c2ccccc2OC)nn1,0.6285714285714287
COc1cc(S(=O)(=O)N2CCN=C2Cc2ccccc2)ccc1Cl,0.6285714285714287
Cc1ccc(Cn2ncc3c(N)ncnc32)cc1,0.6285714285714287
C[C@@H](NC(=O)NC[C@H]1CCCN(c2ncccn2)C1)C1CCOCC1,0.6285714285714287
O=C1O[C@H](C(=O)Nc2ccnc3ccnn23)Cc2ccccc21,0.6285714285714287
Cc1cccn2c(=O)c(C(=O)NC[C@H]3CCO[C@@H]3C(C)C)cnc12,0.6214285714285713
C=CCN(C(=O)C/C=C/c1ccc(C)cc1)[C@@H]1CCS(=O)(=O)C1,0.6214285714285713
CCN(CC)S(=O)(=O)c1ccc2nc(-c3ccncc3)cc(C(=O)[O-])c2c1,0.6214285714285713
C=CCN1C(=O)/C(=C/c2ccccc2F)S/C1=N\S(=O)(=O)c1cccs1,0.6214285714285713
COc1ccc([C@@H]([NH2+]Cc2ccc(Cl)nc2)c2ccc(F)cc2)cc1,0.6214285714285713
CCn1cc(/C=C/C(=O)c2ccc3ccccc3c2)cn1,0.6214285714285713
C[C@@H]1CCO[C@@H]1C(=O)N1CC[C@H](C(N)=O)c2ccccc21,0.6214285714285713
CCc1ccc(N(Cc2ccc(C)s2)C(=O)c2ccc(=O)n(C)n2)cc1,0.6142857142857142
CC[C@@H](NC(=O)[C@H](C)n1cccn1)c1ccc(C)c(F)c1,0.6142857142857142
C[C@@H](NC(=O)Nc1ccn(-c2ncccc2Cl)n1)[C@@H]1CCCO1,0.6142857142857142
c1ccc2nc(NCCCc3nc4ccccc4[nH]3)cnc2c1,0.6142857142857142
O=S(=O)(Nc1ccc(N2CCCS2(=O)=O)cc1)c1ccc(F)c(Cl)c1,0.6142857142857142
C[C@@H]1CC(Nc2cncc(-c3nncn3C)c2)C[C@@H](C)C1,0.6071428571428571
CC(C)[C@@H](Oc1cccc(Cl)c1)C(=O)N1CCC(n2cccn2)CC1,0.6071428571428571
Cc1ccc(C#N)cc1S(=O)(=O)NCc1ccnc(OC(C)(C)C)c1,0.6071428571428571
Cc1noc(C)c1C[C@H](C)C(=O)N[C@@H](C)C1CCCCC1,0.6071428571428571
CCCc1cc(C(=O)NNC(=O)c2cccc(Br)c2)[nH]n1,0.6071428571428571
CCOC(=O)[C@]1(Cc2cccc(Cl)c2)CCCN(C(=O)c2ccnn2C)C1,0.6071428571428571
O=C(Cc1cccc(F)c1F)Nc1cccc(Br)n1,0.6071428571428571
CCCc1cc(NC(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)n(C)n1,0.6
COC(=O)[C@](NC(=O)c1cccc(Cl)c1)(Nc1ccc(Br)c[nH+]1)C(F)(F)F,0.6
CN(CCc1ccc(F)cc1)c1cc(Br)cc(F)c1C(N)=O,0.6
CC(C)NC(=O)Nc1cccc(C(=O)N(C)Cc2nnc(C3CC3)n2C)c1,0.6
COc1ccc(C(=O)/C=C(\C)Nc2ccc(F)cc2F)cc1,0.6
CCOC[C@H]1CC[NH+](Cc2ccc(-c3nc4ccccc4s3)o2)C1,0.6
C[C@H]([NH2+]Cc1nc(Cc2ccccc2)no1)[C@@H](C)n1cccn1,0.6
C[C@@H](NC(=O)COC(=O)/C=C/c1ccc(Cl)cc1)c1ccccc1,0.5928571428571429
CCc1nnc(-c2cc3ccccc3n2CC(=O)NC(C)(C)C)o1,0.5928571428571429
CC[C@@H]1CCCCN1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1,0.5928571428571429
CCCCNC(=O)CCc1c(C)nc2c3ccccc3nn2c1C,0.5928571428571429
CCCCC(=O)NC(=S)Nc1ccccc1C(=O)N1CCOCC1,0.5857142857142856
Cc1occc1C(=O)/C(C#N)=C\c1cccc(C(F)(F)F)c1,0.5857142857142856
Cc1ccc(C(=O)N[C@H]2CCC[NH2+][C@H]2C)cc1F,0.5857142857142856
O=C1NC(=S)NC(=O)C1=CNc1ccc([N+](=O)[O-])cc1O,0.5857142857142856
C=CCOC(=O)C1=C(C)N=C2S[C@H](C)C(=O)N2[C@H]1c1ccc(F)cc1,0.5857142857142856
CCc1ccc(-c2nc(C(=O)N3CCO[C@H](CC)C3)cs2)cc1,0.5857142857142856
O=C(N[C@@H](CO)c1ccco1)c1cc(Cl)ccc1OC1CCCC1,0.5857142857142856
CCOc1cccc(NC(=O)CCc2ccc(N)cc2)c1,0.5785714285714285
N#Cc1ccnc(N2CCC([NH2+]C[C@@H]3CCCO3)CC2)c1,0.5785714285714285
COc1ccccc1NC(=O)[C@@H]1CCCN(C(=O)Nc2cccs2)C1,0.5785714285714285
COc1cc(NC(=O)[C@H](C)Sc2ccccc2Cl)cc(OC)c1,0.5785714285714285
CCOC(=O)c1nnc2ccccc2c1N1CC[C@@H]([NH+](CC)CC)C1,0.5714285714285714
O=C(NCCCc1ccccc1)C1CCN(C(=O)[C@@H]2CC(=O)N(c3ccccc3)C2)CC1,0.5714285714285714
CCC1(CC)[C@@H](NC(=O)Nc2ccc(C(=O)NC)cc2)[C@H](C)[C@@H]1OC,0.5642857142857143
CC[C@H]1CC(=O)N(Cc2ccccc2C#CCCO)C1,0.5642857142857143
CCOC(=O)c1cccc(NC(=O)c2cn[nH]c2C)c1,0.5642857142857143
CCN(CC)C(=O)C[C@@H](C)[NH2+][C@H](C)c1cccc(F)c1F,0.5571428571428572
COC(=O)Cc1csc(NC(=O)Cc2coc3cc(C)ccc23)n1,0.5571428571428572
O=C(O[C@H]1CCOC1)C1(c2ccc(Cl)c(Cl)c2)CCC1,0.5571428571428572
COc1cc(C)ccc1OCC(=O)Nc1nnc(C)s1,0.5571428571428572
CCOC(=O)C(C)(C)c1nc(-c2ccccc2)no1,0.5571428571428572
CC[NH2+][C@@H](CC)c1ccccc1OCc1cccc(F)c1,0.5571428571428572
CCC(CC)C(=O)Nc1cnn(-c2ccccc2F)c1,0.5571428571428572
CC[C@@H](C)NC(=O)c1ccc2c(c1)CCCN2S(C)(=O)=O,0.5571428571428572
COC(=O)C1(NC(=O)[C@H]2C[C@H]2c2c(F)cccc2F)CCSCC1,0.55
Cc1ccc([C@@H](C)NC(=O)N[C@@H](CCO)c2cccs2)cc1,0.55
Cc1nnccc1C(=O)N[C@H](C)c1ccc(Cl)s1,0.55
CC[C@H](NC(=O)NCc1c(C)noc1C)c1ccc(OC)cc1,0.55
CCN1CCC(=NNC(=O)c2ccccc2)CC1,0.55
CCC[C@@H]1CN(C(=O)C(=O)Nc2ccc(C)nc2Cl)CCO1,0.5428571428571428
CC[C@@H](CC(=O)NC1(C(=O)OC)CCSCC1)c1ccccc1,0.5428571428571428
Cc1ccc(C)c(-n2c(SCCCCCO)nc3ccccc3c2=O)c1,0.5428571428571428
CC(=O)c1c(O)cccc1COc1ccccc1,0.5357142857142857
COc1cccc(COc2ccc(OC)cc2CCl)c1,0.5357142857142857
COC(=O)[C@@H](C)Sc1nnc(Nc2cccc(Br)c2)s1,0.5357142857142857
O=C(NCc1cccs1)C1(c2cccc(Cl)c2)CCC1,0.5357142857142857
COCCN1C[C@H](C(=O)N(Cc2cccc(Cl)c2)C(C)C)CC1=O,0.5357142857142857
Cc1ccc(CNC(=O)NCc2nnc3n2CCC3)s1,0.5357142857142857
CCC[NH2+][C@H](Cc1nn(C)c2ccccc12)c1ncc[nH]1,0.5357142857142857
COc1ccc(C(=O)N(C)[C@@H](C)C/C(N)=N/O)cc1O,0.5285714285714286
N#CC1(NC(=O)COc2cccc(Cl)c2)CCCC1,0.5285714285714286
CCOC(=O)[C@H]1C=C(C#N)O[C@@H](c2ccc(C)cc2)C1,0.5285714285714286
O=C(Cn1nnn(-c2cccs2)c1=O)OC1CCCCC1,0.5285714285714286
COc1cccc([C@@H](C)[NH2+]CCOc2ncccc2Cl)c1,0.5285714285714286
CCCC(=O)N[C@@H]1CCC[NH+](Cc2ncccc2C)C1,0.5285714285714286
C[C@H](NC(=O)Cc1ccc[nH]1)C(=O)N1CCCC[C@H]1C,0.5285714285714286
CCOC(=O)[C@H]1CCCN(C(=O)c2cc(C(C)C)n(C)n2)C1,0.5285714285714286
C[C@@H]1CN(C(=O)c2cc(Br)cn2C)CC[C@H]1[NH3+],0.5214285714285715
CCn1cc(C(=O)N[C@H]2CC(=O)N(C)C2)c(C(C)C)n1,0.5214285714285715
COc1ccc([C@@H](NC(=O)Nc2cc(C)ccc2Cl)C2CCOCC2)cc1,0.5214285714285715
C[C@H]([NH3+])c1nc2cc(C(F)(F)F)ccc2n1C,0.5214285714285715
CCCOc1ccc(Br)cc1C[NH+]1CCC([C@@H](C)O)CC1,0.5214285714285715
O=C(Nc1ccccc1F)c1cc2ccccc2c2cccnc12,0.5214285714285715
CCC[NH2+][C@@H]1COC[C@H]1C(=O)NCc1cscc1C,0.5142857142857143
CCC[C@]1(C(=O)N[C@@H]2CONC2=O)CC[NH2+]C1,0.5142857142857143
Cc1cc(C)cc(OCC(C)(C)C[NH2+]C2CC2)c1,0.5142857142857143
CCc1ccc(CNC(=O)c2ccc(-c3nccnc3N3CCCCC3)cc2)cc1,0.5071428571428571
CC(C)N(C)C(=O)[C@H]1CSCN1C(=O)/C=C/SCc1ccco1,0.5071428571428571