protein_id stringlengths 6 10 | protein_names stringlengths 2 561 | protein_function stringlengths 0 4.53k | organism stringclasses 355
values | length float64 21 16k | subcellular_location stringlengths 0 5.89k | sequence stringlengths 21 16k | go_ids listlengths 2 464 | go_bp listlengths 0 437 | go_mf listlengths 0 51 | go_cc listlengths 0 61 | structure_path stringlengths 0 29 | interpro_location stringlengths 3 529 | interpro_formatted stringlengths 0 1.79k | ppi_formatted stringlengths 0 811 | go_pred stringlengths 382 15k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P31037 | Protein A49R | Plays a role in the inhibition of host NF-kappa-B activation. Interacts with host BTRC and thereby diminishes ubiquitination of NF- kappa-B inhibitor alpha/NFKBIA. This stabilizes NFKBIA and its interaction with NF-kappaB, so retaining p65/RELA in the cytoplasm and preventing NF-kappa-B-dependent gene expression | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain | 162 | Host cytoplasm. Host nucleus | MDEAYYSGNLESVLGYVSDMHTELASISQLVIAKIETIDNDILNKDIVNFIMCRSNLDNPFISFLDTVYTIIDQENYQTELINSLDDNEIIDCIVNKFMSFYKDNLENIVDAIITLKYIMNNPDFKTTYAEVLGSRIADIDIKQVIRENILQLSNDIRERYL | [
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035556",
"GO:0035821",
"GO:0038061",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029",
"GO:0065007"... | [
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035556",
"GO:0035821",
"GO:0038061",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029",
"GO:0065007"... | [
"GO:0003674",
"GO:0140311",
"GO:0140313"
] | [
"GO:0005575",
"GO:0018995",
"GO:0030430",
"GO:0033643",
"GO:0033646",
"GO:0043656",
"GO:0044217",
"GO:0110165"
] | {"IPR009473": [1, 162]} | - IPR009473: Orthopoxvirus A49 (family) [1-162] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO... | ||
Q59RR0 | Cell wall transcription factor ACE2 | Transcription factor involved in the RAM (regulation of ACE2 transcription factor and polarized morphogenesis) signaling network that regulates polarized morphogenesis. Regulates expression of genes involved in cell separation such as CHT3, DSE1, and SCW11; or other cell wall genes such as ASH1, DSE4, PIR1, PRY2, and R... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 783 | Nucleus. Note=Localized in the nuclei of daughter cells | MHWKFSNFRKYHLSFHLNLFDLSLFFISFYCFPILYICFFNQVHSFRSTQPSLIMNKFDLFDDYSTKGSTIPLPNENFDQLFLSSEANDMEFLFNETLMGLQDLDVPSGYGIPQNTINNDFQHTPNKSKSHSRQYSGTAIFGFADHNKDLSINGVNNDLCKQSNKAINTQSVSPGELLKRSRGSQTPTPTSALPDTAQDILDFNFEEKPILLLEEDELEEEKHKQQQRMMTQSSPLKRVTTPSQSPFVQQPQTMKQRKPHKKTNEYIVANENPNSYKFPPSPSPTAKRQQYPPSSPIPYNPKSDSVGGNSYSAKYLQSLN... | [
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010564",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0016043",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010564",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0016043",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q59RR0-F1-model_v6.pdb | {"IPR036236": [647, 701], "IPR013087": [649, 706]} | - IPR013087: Zinc finger C2H2-type (domain) [649-706]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [647-701] | - Serine/threonine-protein kinase CBK1
- Cdh1p
- CBK1 kinase activator protein MOB2
- Biofilm and cell wall regulator 1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biolog... |
P83773 | Acetyl-CoA hydrolase | Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 524 | Cytoplasm | MSAILKQRVRYAPYLKKLRTGEQCIDLFKHGQYLGWSGFTGVGAPKVIPTTLVDHVEKNNLQGKLGFHLFVGASAGPEESRWAENNMILTRAPHQVGKPIAAAINDGRTQFFDKHLSMFPQDLTYGFYTKDKPNGSNLDYTIIEATAITEDGSIVPGPAVGASPEMISVSDKIIIEVNTKTPSFEGIHDIDMPVNPPFRQPYPHTSADFKIGKTAIPVDPEKVVAIVESTSGDKVPPNTPSDEQSRGIANHLIEFLEHEVKQGRLPANLHPLQSGIGNIANAVVEGLASSNFKNLTVWTEVLQDSFLDFFESGSLDYATA... | [
"GO:0006082",
"GO:0006083",
"GO:0008150",
"GO:0008152",
"GO:0009268",
"GO:0009628",
"GO:0009987",
"GO:0010446",
"GO:0019752",
"GO:0032787",
"GO:0043436",
"GO:0044281",
"GO:0050896",
"GO:0051716",
"GO:0071214",
"GO:0071467",
"GO:0071469",
"GO:0104004",
"GO:0003674",
"GO:0003824"... | [
"GO:0006082",
"GO:0006083",
"GO:0008150",
"GO:0008152",
"GO:0009268",
"GO:0009628",
"GO:0009987",
"GO:0010446",
"GO:0019752",
"GO:0032787",
"GO:0043436",
"GO:0044281",
"GO:0050896",
"GO:0051716",
"GO:0071214",
"GO:0071467",
"GO:0071469",
"GO:0104004"
] | [
"GO:0003674",
"GO:0003824",
"GO:0003986",
"GO:0016289",
"GO:0016787",
"GO:0016788",
"GO:0016790",
"GO:0160215"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0005829",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-P83773-F1-model_v6.pdb | {"IPR037171": [6, 516], "IPR038460": [350, 496], "IPR046433": [2, 520], "IPR003702": [10, 228], "IPR026888": [329, 479]} | - IPR003702: Acetyl-CoA hydrolase/transferase, N-terminal (domain) [10-228]
- IPR038460: Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily (homologous_superfamily) [350-496]
- IPR026888: Acetyl-CoA hydrolase/transferase, C-terminal domain (domain) [329-479]
- IPR037171: NagB/RpiA transferase-like (homolog... | - Acetyl-coenzyme A synthetase 2
- Malate synthase
- Acetyl-coenzyme A synthetase
- Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
- Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial
- Acetyl-CoA acetyltransferase
- Aldehyde dehydrogenase (NAD(P)(+))
- Acetyltransferase component of pyru... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0008410 (CoA-transferase ac... |
P87017 | 5'-hydroxyaverantin dehydrogenase | 5'-hydroxyaverantin dehydrogenase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide- derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatox... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 278 | Cytoplasm, cytosol | MEVLDTTVDLGTLQGKSALITGGASGIGLATARAWAAAGMYVTIADIQPLETGQNILADLAGGHVHYVCCDVTSWESQITAFKEAIQFTPSKALDIVAAFAGVSFAGGNQVDHVLAAGDPRLDVNPSPPDIRNIQVNLIGVYYTSWLGLYYLRLSPTNKAANPSPDKSLILMGSIGSYMDSPKASTYPASKFGVRGLFRSTRARTRELGVRCNLLAPWFIDTPLIAPMKKAMAARGIDMAQRLTFASVDACVEAATTCAANPQLHGTPPIRYAYCLKT | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-P87017-F1-model_v6.pdb | {"IPR036291": [12, 265], "IPR002347": [16, 229], "IPR020904": [174, 202]} | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [12-265]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [174-202]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [16-229] | - Versicolorin B synthase
- Averantin hydroxylase | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0042802 (identical protein binding), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0046983 (protein dimeriza... |
Q12120 | Sterigmatocystin 8-O-methyltransferase | Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), afl... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 418 | Cytoplasm. Vacuole | MALPSKAALVGLANTLSEQVKRYLATAGETKSPEDHKLCIESERTPSSNEHAQAWEIVRTCDRIGSLVHGPVPWLLSNALSHLDSACLAAATHLNLQDIIVDGPSPTSLDTIVAATGVSEDLLRRILRGCAQRFIFEEVAPDQYAHTDASKMLRVTGIHALVGFSCDEVMRSGASFSDFLQQTKGKPPSWNVPSPFSLAFDPTKGLFDYYSTVDEVRGRRFDLGMGGTEATKPLVEEMFDFSSLPEGSTVVDVGGGRGHLSRRVSQKHPHLRFIVQDLPAVIHGVEDTDKVTMMEHDIRRPNPVRGADVYLLRSILHDYP... | [
"GO:0003674",
"GO:0003824",
"GO:0008168",
"GO:0008171",
"GO:0016740",
"GO:0016741",
"GO:0047146",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0008168",
"GO:0008171",
"GO:0016740",
"GO:0016741",
"GO:0047146"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-Q12120-F1-model_v6.pdb | {"IPR036390": [65, 154], "IPR036388": [71, 153], "IPR029063": [158, 404], "IPR016461": [76, 415], "IPR012967": [80, 153], "IPR001077": [206, 387]} | - IPR016461: O-methyltransferase-like (family) [76-415]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [71-153]
- IPR012967: O-methyltransferase, dimerisation domain (domain) [80-153]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [65-154]
- IPR... | - O-methylsterigmatocystin oxidoreductase
- Demethylsterigmatocystin 6-O-methyltransferase
- O-methyltransferase
- O-methyltransferase
- Aflatoxin biosynthesis regulatory protein | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008171 (O-methyltransferase activity)
Biological Process (BP): GO:0008150 (biologi... |
O13345 | O-methylsterigmatocystin oxidoreductase | O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), af... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 528 | MIYSIIICAGALLGFLILQKLLAPKDTRPPLPPGPWRKPIIGNLTDFPPKGTPEWLFWAKHHERYGPMSSLEVMGQTIIMINDAHLGIEIMHKKSALSQMIPDAPFAHMAGWGMSLATERNKQAWKTIRANMKQEIGTRRAIATFHPKMEIGIRRFLLRTLDNPDDLRFHIRKEANAFMMDVAYGYTIAPHGKDELYDLTQQSVRQFSHIFSPGEWSVNFFPILRYVPSWFPGASFQIKAAEYKRTIERMTMVPYLWIKDQVARGCTRPSILLRLLQKGHYESGSHQEQVLVWTNAEFVMGGSDTTVSAVSSFFVAMALY... | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491"
] | [] | AF-O13345-F1-model_v6.pdb | {"IPR036396": [23, 496], "IPR050364": [6, 507], "IPR001128": [32, 489], "IPR002401": [62, 463], "IPR017972": [433, 442]} | - IPR017972: Cytochrome P450, conserved site (conserved_site) [433-442]
- IPR001128: Cytochrome P450 (family) [32-489]
- IPR002401: Cytochrome P450, E-class, group I (family) [62-463]
- IPR050364: Cytochrome P450 monooxygenase, fungi (family) [6-507]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [23... | - Sterigmatocystin 8-O-methyltransferase | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process),... | |
Q59Z29 | Iron-regulated transcriptional activator AFT2 | Transcription factor involved in iron metabolism, oxidative stress, surface adhesion, hyphal development and virulence. Functions as a negative regulator of MRS4 expression through the CACCC AFT-type sequence in a gene dose-dependent fashion. Acts as a repressor in flocculation, plastic adhesion, and surface hydrophobi... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 798 | Nucleus | MTDRVTHRVSLDDLNLEKQKFDSKDDIKPWLQDNLQSTKGINVVIERSDTSKIIFKCKNKEKKTKIVESKKTASKTMIRKHTSCPFKIRANYSVRNKVWTLSIVSDEHDHVVDLPRSFVGKNLISNTIPGSSLNVLDSVAPRSNKKGIKPTSEIANTPSVTSYSPSCAVKRNEDVDAPKISSKKARNLTKKPSTQSTRSSSSSDGSSIVSFGSLTSQSSSTSLPENYKGQVPTSMDSMVVEESLTGKSLKPAASHPVKRKNMKANTMKKSKKLKQNPIVVSPIEEDSNLNSFDDANIDLQRQQSLQSPLSHLVQNQDPIS... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006873",
"GO:0006879",
"GO:0006950",
"GO:0006979",
"GO:0007155",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006873",
"GO:0006879",
"GO:0006950",
"GO:0006979",
"GO:0007155",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q59Z29-F1-model_v6.pdb | {"IPR014842": [21, 111]} | - IPR014842: Iron-regulated transcriptional activator AFT (family) [21-111] | - Monothiol glutaredoxin
- Ccc1p | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biolog... |
Q8R4S7 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus caroli (Ryukyu mouse) (Ricefield mouse) | 854 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQTAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPSGCDAKGQLILGYTEVELCTRGSGY... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S7-F1-model_v6.pdb | {"IPR036638": [30, 80], "IPR035965": [120, 386], "IPR039091": [6, 811], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 384], "IPR013767": [112, 185], "IPR013655": [298, 380], "IPR001610": [346, 387]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-386]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-185]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S6 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus musculus castaneus (Southeastern Asian house mouse) | 848 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIH... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S6-F1-model_v6.pdb | {"IPR036638": [30, 80], "IPR035965": [120, 382], "IPR039091": [6, 791], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 380], "IPR013767": [112, 177], "IPR013655": [293, 376], "IPR001610": [342, 383]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-382]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-177]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S4 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus spicilegus (Steppe mouse) | 854 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGY... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S4-F1-model_v6.pdb | {"IPR036638": [30, 80], "IPR035965": [120, 386], "IPR039091": [6, 803], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 384], "IPR013767": [112, 184], "IPR013655": [297, 380], "IPR001610": [346, 387]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-386]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-184]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S2 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus spretus (Western Mediterranean mouse) (Algerian mouse) | 854 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQNLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGY... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S2-F1-model_v6.pdb | {"IPR036638": [30, 80], "IPR035965": [120, 386], "IPR039091": [6, 806], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [109, 384], "IPR013767": [112, 184], "IPR013655": [297, 380], "IPR001610": [346, 387]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-386]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-184]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8BS35 | Alkylglycerol monooxygenase | Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity) | Mus musculus (Mouse) | 447 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MRSPGAQDNVSVSQGMRAMFYMMEPSETAFQTVEEVPDYVKKATPFFIFLILLELVISWILKGKPSGRLDDALTSISAGVVSRLPSLFFRSLEVTSYIYIWENYRLLELPWDSTWTWYFTFLGVDFGYYWFHRMAHEINIFWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFIPPSVFAVHIQFNLLYQFWIHTEIIRTLGPLEVILNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFNVQFHHLLYIWTTFWTTPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEV... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486",
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491",
"GO:0016705"... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491",
"GO:0016705",
"GO:0016714",
"GO:0050479"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | AF-Q8BS35-F1-model_v6.pdb | {"IPR051689": [7, 445], "IPR006694": [118, 249], "IPR056853": [335, 422]} | - IPR056853: Alkylglycerol monooxygenase, C-terminal (domain) [335-422]
- IPR006694: Fatty acid hydroxylase (domain) [118-249]
- IPR051689: Sterol desaturase/TMEM195-like (family) [7-445] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016714 (oxidoreductase activity, a... | |
Q59L12 | Agglutinin-like protein 3 | Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent ... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,155 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Covers the surface of the germ tube | MLQQYTLLLIYLSVATAKTITGVFNSFNSLTWSNAATYNYKGPGTPTWNAVLGWSLDGTSASPGDTFTLNMPCVFKFTTSQTSVDLTAHGVKYATCQFQAGEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLFVAPQCANGYTSGTMGFANTYGDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNGIFITYKNVPAGYRPFVDAYISATDVNSYTLSYANEYTCAGGYWQRAPFTLRWTGYRNSDA... | [
"GO:0000041",
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006826",
"GO:0006873",
"GO:0006878",
"GO:0006879",
"GO:0006897",
"GO:0007155",
"GO:0008150",
"GO:0009595",
"GO:0009602",
"GO:0009603",
"GO:0009605",
"GO:0009607",
"GO:0009608",
"GO:0009610",
"GO:0009620",
"GO:0009987"... | [
"GO:0000041",
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006826",
"GO:0006873",
"GO:0006878",
"GO:0006879",
"GO:0006897",
"GO:0007155",
"GO:0008150",
"GO:0009595",
"GO:0009602",
"GO:0009603",
"GO:0009605",
"GO:0009607",
"GO:0009608",
"GO:0009610",
"GO:0009620",
"GO:0009987"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0030984",
"GO:0030985",
"GO:0050839"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030445",
"GO:0030446",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-Q59L12-F1-model_v6.pdb | {"IPR011252": [17, 177], "IPR008966": [24, 174], "IPR043063": [178, 329], "IPR033504": [1, 693], "IPR024672": [53, 298], "IPR008440": [365, 863]} | - IPR008966: Adhesion domain superfamily (homologous_superfamily) [24-174]
- IPR043063: Agglutinin-like protein, N-terminal, N2 subdomain (homologous_superfamily) [178-329]
- IPR008440: Agglutinin-like protein repeat (repeat) [365-863]
- IPR033504: Agglutinin-like protein (family) [1-693]
- IPR024672: Agglutinin-like p... | - Extent of cell elongation protein 1
- Hyphal wall protein 1
- Hyphally regulated cell wall protein 1
- Cell wall protein RBT1
- Enhanced filamentous growth protein 1
- Biofilm and cell wall regulator 1
- Transcriptional regulatory protein UME6
- Secreted aspartic protease 4
- Secreted aspartic protease 5
- Cell wall ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0050840 (extracellular matrix binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0001968 (fibronectin binding), GO:0043236 (laminin binding)
Biological Process (BP): GO:0008150 (biologica... |
Q5A8T7 | Agglutinin-like protein 5 | Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,347 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer | MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDA... | [
"GO:0007155",
"GO:0007160",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044406",
"GO:0044409",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098609"... | [
"GO:0007155",
"GO:0007160",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044406",
"GO:0044409",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098609"... | [
"GO:0001968",
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042277"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q5A8T7-F1-model_v6.pdb | {"IPR011252": [17, 177], "IPR008966": [25, 174], "IPR043063": [178, 329], "IPR033504": [1, 535], "IPR024672": [53, 298], "IPR008440": [365, 577]} | - IPR008966: Adhesion domain superfamily (homologous_superfamily) [25-174]
- IPR043063: Agglutinin-like protein, N-terminal, N2 subdomain (homologous_superfamily) [178-329]
- IPR008440: Agglutinin-like protein repeat (repeat) [365-577]
- IPR033504: Agglutinin-like protein (family) [1-535]
- IPR024672: Agglutinin-like p... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0050840 (extracellular matrix binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0001968 (fibronectin binding), GO:0043236 (laminin binding)
Biological Process (BP): GO:0008150 (biologica... | |
Q5A312 | Agglutinin-like protein 7 | Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,568 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer | MKKLYLLYLLASFTTVISKEVTGVFNQFNSLIWSYTYRARYEEISTLTAKAQLEWALDGTIASPGDTFTLVMPCVYKFMTYETSVQLTANSIAYATCDFDAGEDTKSFSSLKCTVTDELTEDTSVFGSVILPIAFNVGGSGSKSTITDSKCFSSGYNTVTFFDGNNQLSTTANFLPRRELAFGLVVSQRLSMSLDTMTNFVMSTPCFMGYQSGKLGFTSNDDDFEIDCSSIHVGITNEINDWSMPVSSVPFDHTIRCTSRALYIEFKTIPAGYRPFVDAIVQIPTTEPFFVKYTNEFACVNGIYTSIPFTSFFSQPILYD... | [
"GO:0007155",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044419",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [
"GO:0007155",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044419",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [] | [] | AF-Q5A312-F1-model_v6.pdb | {"IPR011252": [18, 176], "IPR008966": [49, 174], "IPR043063": [182, 326], "IPR033504": [3, 523], "IPR024672": [54, 299], "IPR008440": [403, 543]} | - IPR008966: Adhesion domain superfamily (homologous_superfamily) [49-174]
- IPR043063: Agglutinin-like protein, N-terminal, N2 subdomain (homologous_superfamily) [182-326]
- IPR008440: Agglutinin-like protein repeat (repeat) [403-543]
- IPR033504: Agglutinin-like protein (family) [3-523]
- IPR024672: Agglutinin-like p... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0050840 (extracellular matrix binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0001968 (fibronectin binding), GO:0043236 (laminin binding)
Biological Process (BP): GO:0008150 (biologica... | |
O74254 | Glucoamylase 1 | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 946 | Secreted, cell wall. Membrane; Peripheral membrane protein | MKLLSKVFVTALGLTSIVNAAPTSSSSAEEAQKTVPVELSIGVKQLPNIHNDSAVDANAVAKGYSLVNVSLTARGLTGILKLKEATNIYGYDFEYLNLSVEYQSDTRLNVHIEPTDLTDVFVLPEELVVKPKLEGDAKTFNFENSDLVFEYDEEDFGFEVLRSSTREVLFSTKGNPLVFSNQFIQFNTTLPKGHSITGLGESIHGSLNEPGVVKTLYANDIADPIDGNIYGVHPVYYDQRYNTNTTHAVYWRTSAIQEVVVGETSLTWRALSGVIDLYFFSGPDPKDVIQQYVSEIGLPAMQPYWALGYHQCRWGYDTVE... | [
"GO:0008150",
"GO:0009987",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743",
"GO:0005575",
"GO:0005576",
"GO:0110165"
] | [
"GO:0008150",
"GO:0009987",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0110165"
] | AF-O74254-F1-model_v6.pdb | {"IPR011013": [60, 285], "IPR017853": [286, 731], "IPR013780": [716, 946], "IPR000322": [299, 723], "IPR048395": [731, 821], "IPR030459": [655, 685], "IPR030458": [458, 465]} | - IPR030458: Glycosyl hydrolases family 31, active site (active_site) [458-465]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [286-731]
- IPR030459: Glycosyl hydrolases family 31, conserved site (conserved_site) [655-685]
- IPR000322: Glycoside hydrolase family 31, TIM barrel domain (domain) [29... | - glucan 1,4-alpha-glucosidase
- Glucan 1,3-beta-glucosidase BGL2
- Glucoamylase 1
- Glucan 1,3-beta-glucosidase
- Hexokinase-2
- Alpha-glucosidase
- beta-glucosidase
- Glycosyl hydrolase family 13 catalytic domain-containing protein
- beta-glucosidase
- Phosphotransferase | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015926 (glucosidase activity), GO:0090599 (alpha-glucosidase activ... | |
Q59KZ1 | Aminopeptidase 2 | Metalloprotease that specifically hydrolyzes peptides with N- terminal alanine, arginine and leucine residues | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 924 | Secreted, cell wall | MASNNTSQRSGFSSFFCRLKTYFCNHFLCLFVLSFFPLSFRRLCLLCHLCEKSNLWLSSDNSASVVKQEREVLPTNVKPLHYDLTIEPIFDNFTFKGEETIDFQVNEKTNFITLNSLEIEVQEAKIDGKSVTDISFDAGKQTVTFKFDDDLSTGSIAKLYIKFTGELNDKMAGFYRASYQEDGKTKYMATTQMEPTDCRRAFPSYDEPAAKSKFTISLIADKELVCLSNSSEKETVSLDGNKKKVTFQTTPLMSTYLVAFIVGDLRYISNDNYRVPIRVYSTPGTEHLGEYSANIAAQTLKFFDQQFGIDYPYDKLDMVA... | [
"GO:0003674",
"GO:0003824",
"GO:0004177",
"GO:0008233",
"GO:0008235",
"GO:0008236",
"GO:0008237",
"GO:0008238",
"GO:0016787",
"GO:0017171",
"GO:0070006",
"GO:0140096",
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004177",
"GO:0008233",
"GO:0008235",
"GO:0008236",
"GO:0008237",
"GO:0008238",
"GO:0016787",
"GO:0017171",
"GO:0070006",
"GO:0140096"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q59KZ1-F1-model_v6.pdb | {"IPR042097": [58, 264], "IPR027268": [268, 513], "IPR050344": [61, 918], "IPR034016": [80, 510], "IPR001930": [199, 391], "IPR045357": [78, 257], "IPR014782": [291, 508], "IPR024571": [582, 900]} | - IPR034016: Aminopeptidase N-type (family) [80-510]
- IPR050344: Peptidase M1 family aminopeptidases (family) [61-918]
- IPR027268: Peptidase M4/M1, CTD superfamily (homologous_superfamily) [268-513]
- IPR045357: Aminopeptidase N-like , N-terminal domain (domain) [78-257]
- IPR024571: ERAP1-like C-terminal domain (dom... | - 14-3-3 protein homolog | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity), GO:0008238 (exopeptidase activity), GO:0004177 (aminopeptidase activi... |
Q5AC48 | Actin-related protein 4 | Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 com... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 468 | Nucleus | MATASTTTVYGGDEINAIVLDPGSYTTRIGYAGDDFPKVITSSYYGQVKNDKKKIFGESINVPRANYDIKPILKESIIVDWDAAIEQYQYYFDQQLKVVGPEQPILITEPIWTETSYRQQLVETFFENFEFSGIYLAKSPTCVSFQQGRSNCLVVDLGHDSVSVTPVIDGICLLKSSMKTNYGGKFLSNEIQDYLIDTKKVVMEPSFKIKSKIPTTYPDPPKYELKNNNTIPTSSSSSLSQSFLEFQNEKIYHNFKEILEVPEKNSSSGTTTTTTTTNKDSSRLFELPTGQSIVIDRFKIAESIFDPTIYKFTNSKLSFP... | [
"GO:0003674",
"GO:0003824",
"GO:0004402",
"GO:0008080",
"GO:0010485",
"GO:0016407",
"GO:0016410",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0034212",
"GO:0061733",
"GO:0140096",
"GO:0140186",
"GO:0140993",
"GO:0000123",
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694"... | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004402",
"GO:0008080",
"GO:0010485",
"GO:0016407",
"GO:0016410",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0034212",
"GO:0061733",
"GO:0140096",
"GO:0140186",
"GO:0140993"
] | [
"GO:0000123",
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0031248",
"GO:0032991",
"GO:0035267",
"GO:0043189",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165",
"GO:0140535",
"GO:1902493",
"GO:1902494",
"GO:1902562",
"GO:1990234"
] | AF-Q5AC48-F1-model_v6.pdb | {"IPR043129": [13, 465], "IPR004000": [12, 468], "IPR004001": [448, 456]} | - IPR004001: Actin, conserved site (conserved_site) [448-456]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [13-465]
- IPR004000: Actin family (family) [12-468] | - Actin
- Arp8p
- SWR1-complex protein 4
- Histone acetyltransferase
- Helicase SWR1
- Enhancer of polycomb-like protein 1
- RuvB-like helicase 1
- RuvB-like helicase 2
- Chromatin-remodeling ATPase INO80
- Snf5p | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0004402 (histone acetyltransferase activ... |
Q708S7 | Acid-sensing ion channel 1A | Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory. Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inwar... | Danio rerio (Zebrafish) (Brachydanio rerio) | 501 | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Cell projection, dendrite | MKTSVMDLKVEPMDIDFDQPPPLQVFAHTSTLHGISHIFSYEKITAKCCLWVVFFLSSLTFLMYVCIDRIQFYLEYPHVTKLDEITTPVMVFPAVTICNLNSIRFSRITRNDLYHAGELLALLNSRHEVREAHLVEESVMEVLKSKTDFRSFKPRHFNMWEFYNRTGHDIKDMLLSCQFRGSPCRPEDFSVVFTRYGKCYTFNSGETGPPRVSVKGGMGNGLEIMLDIQQDEYLPVWGESDESSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLVYLPAPWGSCKSTPPSSDYFRAYSISACRTDCETRY... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S7-F1-model_v6.pdb | {"IPR001873": [24, 469], "IPR004724": [136, 480], "IPR020903": [307, 327]} | - IPR001873: Epithelial sodium channel (family) [24-469]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [307-327]
- IPR004724: Epithelial sodium channel, chordates (family) [136-480] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... | |
Q708S8 | Acid-sensing ion channel 1B | Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory. Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inwar... | Danio rerio (Zebrafish) (Brachydanio rerio) | 557 | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Cell projection, dendrite | MVRITCTISFSTDDEPVGRSRQGSFDDHYKRVVWSKDGEQGKYQEEGDDPDAYDGPEDEEAPDISLATFFGGCSLHGANHVFVEDKKFSIRQGLWALVFLLAISMFLLQVVDRVIYYLQYDYVTLLDERNAKNMTFPAITLCNYNTFRRSQLSYSDLLFMGPLLGYEDNMAPGIPLAPEPDRQGSRFSLAEFFNRTRHRMDDMLLECNFAGKECGAEHWREIFTRYGKCYTFNSGQDGRPLLITTKGGMGNGLEIMLDIQQDEYLPVWGETDETTFEAGIKVQIHTQDEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPP... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S8-F1-model_v6.pdb | {"IPR001873": [67, 498], "IPR004724": [191, 514], "IPR020903": [338, 358]} | - IPR001873: Epithelial sodium channel (family) [67-498]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [338-358]
- IPR004724: Epithelial sodium channel, chordates (family) [191-514] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... | |
Q708S6 | Acid-sensing ion channel 1C | Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory. Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inwar... | Danio rerio (Zebrafish) (Brachydanio rerio) | 529 | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Cell projection, dendrite | MTAMKGDSEDSIESMRPSNLQVFANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLLMYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKITKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECFPLNFTTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSEYFSTYSITACRIDCETRYLL... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S6-F1-model_v6.pdb | {"IPR001873": [20, 461], "IPR004724": [140, 475], "IPR020903": [305, 325]} | - IPR001873: Epithelial sodium channel (family) [20-461]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [305-325]
- IPR004724: Epithelial sodium channel, chordates (family) [140-475] | - Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... |
Q708S4 | Acid-sensing ion channel 4-A | Could form pH-gated trimeric sodium channels and function as a postsynaptic excitatory receptors in the nervous system | Danio rerio (Zebrafish) (Brachydanio rerio) | 539 | Cell membrane; Multi-pass membrane protein | MPIEFVCKIKFAEEDEKQKGNQDGDKESLIEESCSPPTKDLAGFASASSLHGINHIFVSGRLGVRQTLWALAFLVSLALFLYQAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRFRFSALTDADIYHLANLTGLPPKNKDGHKPTDLEYPAPDMQDIFNRTGHQLEEMLKSCNFSGQNCSAEDFTVVYTRYGKCYTFNGNKTTSRKTKQGGMGNGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSEQMIPGYDTYSISACRLRCETL... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S4-F1-model_v6.pdb | {"IPR001873": [42, 465], "IPR020903": [308, 328]} | - IPR001873: Epithelial sodium channel (family) [42-465]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [308-328] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... | |
Q708S3 | Acid-sensing ion channel 4-B | Does not exhibit measurable stand-alone pH-gated sodium channel activity but may form pH-gated heterotrimeric sodium channels | Danio rerio (Zebrafish) (Brachydanio rerio) | 558 | Cell membrane; Multi-pass membrane protein | MPIEFVCKIKFAEGEEAKGASTEGGGTGMLDEGLRRQKEGMADLASFASSSSLHGLARALGTSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNFSGQNCSSEDFSVVYTRYGKCYTFNGNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQNEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRASSEPVIPGYDTYSVSACRLH... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S3-F1-model_v6.pdb | {"IPR001873": [40, 467], "IPR020903": [312, 332]} | - IPR001873: Epithelial sodium channel (family) [40-467]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [312-332] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 ... | |
A0A8I3NQW8 | PAT complex subunit Asterix | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occ... | homolog; | 106 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MSTNNMSDPRRPNKVLRYKPPPSECNPALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMTPPW | [
"GO:0006996",
"GO:0007029",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0033036",
"GO:0033365",
"GO:0045048",
"GO:0045184",
"GO:0051179",
"GO:0051205",
"GO:0051234",
"GO:0051641",
"GO:0051668",
"GO:0061024",
"GO:0071840",
"GO:0090150",
"GO:0160063"... | [
"GO:0006996",
"GO:0007029",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0033036",
"GO:0033365",
"GO:0045048",
"GO:0045184",
"GO:0051179",
"GO:0051205",
"GO:0051234",
"GO:0051641",
"GO:0051668",
"GO:0061024",
"GO:0071840",
"GO:0090150",
"GO:0160063"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0005829",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0032991",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0072379",
"GO:0098827",
"GO:0110165",
"GO:0160064"... | AF-A0A8I3NQW8-F1-model_v6.pdb | {"IPR005351": [2, 106]} | - IPR005351: PAT complex subunit Asterix (family) [2-106] | Molecular Function (MF): GO:0003674 (molecular function), GO:0044183 (protein folding chaperone)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular compon... | |
Q5AAU5 | Cell wall acid trehalase ATC1 | Cell wall acid trehalase that catalyzes hydrolysis of the disaccharide trehalose and required for growth on trehalose as carbon source. Plays a role in dimorphic conversion and virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,078 | Secreted, cell wall | MAANSSFFLADNCAPHNQSFIQFCIHAASKKKGRIALMCLANLFLLFSFHLLYARFCSGFPYVVPSTARSTNQIFHTNLEQLVNSPENKQIFSQLKFSDQAFYDPHDNVVGTTEFPVFNQYQRQPYVANGYIGSRIPNLGQGFTYDQLTNSSTANDDDLLNGWPLFNKRYSGAFVAGFYDLQKNTTGTNFAELLENGYESVIAAVPQWTALSLSVEILGKKYTLDPSLEHEAIGDITNYVQNMSLSDGIVTTQFTWLNTFDVKYEILAHRENINLGLVNMQVYNPGNESVQVIVSDVLDFNSSQRCQLNQISHDKNGIYV... | [
"GO:0005975",
"GO:0005984",
"GO:0005991",
"GO:0005993",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009311",
"GO:0009313",
"GO:0009987",
"GO:0016052",
"GO:0044238",
"GO:0046352",
"GO:0003674",
"GO:0003824",
"GO:0004553",
"GO:0004555",
"GO:0015927",
"GO:0016787",
"GO:0016798"... | [
"GO:0005975",
"GO:0005984",
"GO:0005991",
"GO:0005993",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009311",
"GO:0009313",
"GO:0009987",
"GO:0016052",
"GO:0044238",
"GO:0046352"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004553",
"GO:0004555",
"GO:0015927",
"GO:0016787",
"GO:0016798"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-Q5AAU5-F1-model_v6.pdb | {"IPR037018": [109, 379], "IPR011013": [166, 378], "IPR008928": [388, 844], "IPR012341": [437, 771], "IPR005196": [119, 379], "IPR005195": [442, 633]} | - IPR037018: Glycoside hydrolase family 65, N-terminal domain (homologous_superfamily) [109-379]
- IPR005196: Glycoside hydrolase, family 65, N-terminal (domain) [119-379]
- IPR012341: Six-hairpin glycosidase-like superfamily (homologous_superfamily) [437-771]
- IPR008928: Six-hairpin glycosidase superfamily (homologou... | - Trehalase
- Alpha,alpha-trehalose-phosphate synthase [UDP-forming] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015927 (trehalase activity)
Biological Process (BP): GO:0008150 (b... |
Q59U10 | Biofilm and cell wall regulator 1 | Transcription factor which acts as a master regulator of biofilm formation. Biofilms play an important role in pathogenesis and produce many infections such as oropharyngeal candidiasis or vulvovaginal candidiasis. Controls the expression of genes that govern cell-surface properties such as ALS1, ALS3, HWP1 and HYR1. D... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 740 | Nucleus | MSGTSQVLQNDSHQSQHASMAYNQRQPMMYPPPPQQQPLHSQNSLPPLPPIPAPSLPPISNNISNGNTNELNNNNQQQQQHGQPPLPPPPINANQQYYAVPPLRAPPPLNTLSSVVNSLPTLTPTLTNATHSTMSSNSSAESSASSSSNSITKPKSKRSSKGRVFQCTGYPGCNMSFTRSEHLARHKRKHTGERPFTCPYCSKNFSRLDNLRQHKQTVHAYETYLTKDNRDSKLLIERSKSKKKLKQQEKKAQQQAQLQAQAQAQAQAQVHMQQHQQNGYNFQPPYPQFHNQYYANNQYQGPQPPPPPAPQQQVPGQQQP... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [
"GO:0001216",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59U10-F1-model_v6.pdb | {"IPR036236": [170, 216], "IPR051059": [141, 524], "IPR013087": [165, 224]} | - IPR013087: Zinc finger C2H2-type (domain) [165-224]
- IPR051059: Transcription factor verF-like (family) [141-524]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [170-216] | - Transcription activator TEC1
- Enhanced filamentous growth protein 1
- Biofilm regulator 1
- Agglutinin-like protein 3
- Agglutinin-like protein 1
- Hyphal wall protein 1
- Transcription factor ROB1
- Transcription factor NDT80
- Transcriptional repressor TUP1
- Transcriptional repressor TUP1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (... |
P0A6E9 | ATP-dependent dethiobiotin synthetase BioD 2 | Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring | Escherichia coli (strain K12) | 231 | Cytoplasm | MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIANDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLAMLRSVLAVDRVTV | [
"GO:0006082",
"GO:0006766",
"GO:0006768",
"GO:0006790",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009102",
"GO:0009110",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0032787",
"GO:0042364",
"GO:0043436",
"GO:0043603",
"GO:0043604",
"GO:0044272",
"GO:0044281",
"GO:0044283"... | [
"GO:0006082",
"GO:0006766",
"GO:0006768",
"GO:0006790",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009102",
"GO:0009110",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0032787",
"GO:0042364",
"GO:0043436",
"GO:0043603",
"GO:0043604",
"GO:0044272",
"GO:0044281",
"GO:0044283"... | [
"GO:0003674",
"GO:0003824",
"GO:0004141",
"GO:0005488",
"GO:0005515",
"GO:0016874",
"GO:0016879",
"GO:0016882",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | AF-P0A6E9-F1-model_v6.pdb | {"IPR027417": [1, 220], "IPR004472": [1, 220]} | - IPR004472: Dethiobiotin synthase BioD (family) [1-220]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-220] | - Biotin synthase
- Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- 8-amino-7-oxononanoate synthase
- ATP-dependent dethiobiotin synthetase BioD 1
- Malonyl-[acyl-carrier protein] O-methyltransferase
- Pimeloyl-[acyl-carrier protein] methyl ester esterase | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016874 (ligase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate... |
Q59LY1 | Biofilm regulator 1 | Transcription factor required for hyphal growth, biofilm formation, and virulence. Promotes formation of both conventional and pheromone-stimulated biofilms. Binds and recruits HDA1 to promoters of hypha-specific genes in a rapamycin-dependent manner. Involved in the switch between two heritable states, the white and o... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 422 | Nucleus | MSSSSSLSSSTTTATTTSARIRLPSISELTSRSTISGGSNNGNGSALKSQISPRLSDTSRILPSILKNTSGSSTPTSSSTPFKCPPIKSTVGGTLSSGNTQSNYVLGNTKINSLPRLSSPTLPVKVQPQQQPQLPPASSLSPVTRVINTPPQQPQSVSASTSPNTQYQYYQYQQQSSPIQQQQQQQQATPAATPTVMQMAQNQPSHPAPLQYATQQYYPQPVYYQSPAGVPPPPPSVTHQGHIIAVHQHPGHLPQVGVNGMPPNVGYTIVQPEIVNKSTNRCHRCGTTETPEWRRGPKGVRTLCNACGLFHAKLVKRKGA... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170"... | [
"GO:0001216",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59LY1-F1-model_v6.pdb | {"IPR013088": [274, 357], "IPR000679": [276, 331]} | - IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [274-357]
- IPR000679: Zinc finger, GATA-type (domain) [276-331] | - Biofilm and cell wall regulator 1
- Enhanced filamentous growth protein 1
- Transcription activator TEC1
- Transcription factor ROB1
- Transcription factor NDT80
- Transcriptional regulatory protein UME6
- Transcriptional regulator NRG1
- Transcriptional regulator of filamentous growth FLO8
- Repressor of filamentous... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biologica... |
Q2TBE0 | CWF19-like protein 2 | Homo sapiens (Human) | 894 | MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYAT... | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q2TBE0-F1-model_v6.pdb | {"IPR036265": [663, 803], "IPR040194": [76, 890], "IPR006768": [664, 786], "IPR006767": [795, 889]} | - IPR036265: HIT-like superfamily (homologous_superfamily) [663-803]
- IPR006768: Cwf19-like, C-terminal domain-1 (domain) [664-786]
- IPR040194: Cwf19-like protein (family) [76-890]
- IPR006767: Cwf19-like protein, C-terminal domain-2 (domain) [795-889] | - Pre-mRNA-processing factor 17
- Pre-mRNA-processing factor 19
- 116 kDa U5 small nuclear ribonucleoprotein component
- Cell division cycle 5-like protein
- Pre-mRNA-splicing factor SYF2
- Peptidyl-prolyl cis-trans isomerase-like 1
- U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-processing-splicing factor 8
- Pleio... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | ||
P38505 | Calcium-binding protein 1 | Calcium-binding protein which probably acts as a calcium sensor and modulator, contributing to cellular Ca(2+)-mediated signaling. Activates endogenous kinase(s) in a Ca(2+)-dependent manner. Plays a role in regulating actin cytoskeleton dynamics. Regulates the association of actin filaments in a bundle but not actin p... | Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM) | 134 | Cytoplasm. Cell projection, phagocytic cup. Cell projection, pseudopodium. Note=During host erythrocyte phagocytosis, co-localizes with F-actin to the phagocytic cup. Leaves the phagocytic cup before the formation of phagosomes. Co-localizes with FAK in the pseudopodium | MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLEFSL | [
"GO:0001932",
"GO:0008150",
"GO:0019222",
"GO:0030100",
"GO:0031399",
"GO:0032231",
"GO:0032879",
"GO:0032956",
"GO:0032970",
"GO:0033043",
"GO:0042325",
"GO:0043549",
"GO:0044087",
"GO:0045807",
"GO:0045859",
"GO:0048518",
"GO:0048522",
"GO:0048548",
"GO:0048549",
"GO:0050764"... | [
"GO:0001932",
"GO:0008150",
"GO:0019222",
"GO:0030100",
"GO:0031399",
"GO:0032231",
"GO:0032879",
"GO:0032956",
"GO:0032970",
"GO:0033043",
"GO:0042325",
"GO:0043549",
"GO:0044087",
"GO:0045807",
"GO:0045859",
"GO:0048518",
"GO:0048522",
"GO:0048548",
"GO:0048549",
"GO:0050764"... | [
"GO:0003674",
"GO:0003779",
"GO:0003785",
"GO:0005488",
"GO:0005509",
"GO:0005515",
"GO:0008092",
"GO:0036094",
"GO:0043167",
"GO:0043169",
"GO:0044877",
"GO:0046872",
"GO:0051015"
] | [
"GO:0001891",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005886",
"GO:0016020",
"GO:0031143",
"GO:0042995",
"GO:0071944",
"GO:0110165",
"GO:0120025"
] | AF-P38505-F1-model_v6.pdb | {"IPR011992": [4, 131], "IPR039647": [3, 60], "IPR002048": [1, 134], "IPR018247": [10, 129]} | - IPR002048: EF-hand domain (domain) [1-134]
- IPR039647: EF-hand domain pair protein CML-like (family) [3-60]
- IPR011992: EF-hand domain pair (homologous_superfamily) [4-131]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [10-129] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of ... | |
Q1K615 | Beta-apo-4'-carotenal oxygenase | Beta-apo-4'-carotenal oxygenase involved in the last step of synthesis of neurosporaxanthin, a carboxylic apocarotenoid acting as an essential protective pigment and leading to orange pigmentation. Converts the aldehyde beta-apo-4'-carotenal into neurosporaxanthin. Neurosporaxanthin is synthesized from geranyl-geranyl ... | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / | 533 | MAASKVEIAPFEVTPLDAIPAVCSTARATFASHKTKNLQWRLVQLRKLYWALDDFKASLMAALQQDLRKGGYESDFTEVDWVKNDCLHMINNLETFAKTEKLKDLPVTYSMMNFRVKKEPLGTVLIIGPYNFPIQLVLAPLVGAIGAGCTAVIKPSELTPACAMAMKEMIESRLDRDAFAVVNGGVPETNALMEEKWDKIMFTGSAQVGSIIARKAAETLTPVCLELGGRNPAFVTKKANLALAARRLMWGKVLNAGQVCMSHNYVLVDKDVADTFIEFLKIAYKDMFPNGAKASPDLSRIVNARHFNRIKKMLDETKGK... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148",
"GO:0003674",
"GO:0003824",
"GO:0004029",
"GO:0004030"... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004029",
"GO:0004030",
"GO:0016491",
"GO:0016620",
"GO:0016903"
] | [] | AF-Q1K615-F1-model_v6.pdb | {"IPR016161": [21, 464], "IPR016162": [27, 444], "IPR016163": [229, 426], "IPR012394": [17, 486], "IPR015590": [17, 446]} | - IPR012394: Aldehyde dehydrogenase NAD(P)-dependent (family) [17-486]
- IPR016162: Aldehyde dehydrogenase, N-terminal (homologous_superfamily) [27-444]
- IPR016161: Aldehyde/histidinol dehydrogenase (homologous_superfamily) [21-464]
- IPR016163: Aldehyde dehydrogenase, C-terminal (homologous_superfamily) [229-426]
- I... | - Carotenoid dioxygenase
- Peroxisomal membrane protein
- ATPase family AAA domain-containing protein 1
- Peroxin
- Hsc70 cochaperone
- Mitochondrial fission 1 protein
- Bifunctional lycopene cyclase/phytoene synthase | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as accepto... | |
Q59VH7 | Secreted aspartic protease 7 | Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors (By similarity). These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense (By similarity) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 588 | Secreted | MQRVLELLLLSSTALAVIGDGFIALPVHKLQAGEGSAHFPNRLPIFDVVNGVAKSVEDDVNQIIQPIFGNGIFSGGSIQGTHSGNGHSVKYEVSLPSSSSQKGSNGPSSTDNKDTDPSKTGFSLDDLMNSIPTDFWNLIGLNKAPTSSDNGSKDADFTPSAVSQVEQPTSKSVESTAPGPASSASSSSSSEAASSSQPSEDSQPSSSANKKTGAFFLSLDNTQTLYTATLKVGSPAQEVQVMIDTGSSDLWFISSGNSQCKVNGGSIDCDKYGVFDKSKSSTWHDNKTDYSISYYDGDKASGTMGQDNITFADGFSIENA... | [
"GO:0006508",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0003674",
"GO:0003824",
"GO:0004175",
"GO:0004190",
"GO:0008233",
"GO:0016787",
"GO:0070001",
"GO:0140096",
"GO:0005575",
"GO:0005576",
"GO:0031982",
"GO:0043226",
"GO:0043227"... | [
"GO:0006508",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019538",
"GO:0043170",
"GO:0044238"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004175",
"GO:0004190",
"GO:0008233",
"GO:0016787",
"GO:0070001",
"GO:0140096"
] | [
"GO:0005575",
"GO:0005576",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0110165",
"GO:1903561"
] | AF-Q59VH7-F1-model_v6.pdb | {"IPR021109": [211, 587], "IPR001461": [186, 575], "IPR033876": [224, 576], "IPR033121": [226, 576], "IPR001969": [241, 252]} | - IPR001969: Aspartic peptidase, active site (active_site) [241-252]
- IPR033876: Secreted aspartic endopeptidase (domain) [224-576]
- IPR001461: Aspartic peptidase A1 (family) [186-575]
- IPR033121: Peptidase family A1 domain (domain) [226-576]
- IPR021109: Aspartic peptidase domain superfamily (homologous_superfamily... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0070001 (aspartic-type peptidase activity), GO:0004190 (aspartic-type... | |
A0A2H1A5W4 | Cell wall integrity transcriptional regulator CAS5 | Transcription factor involved in the cell wall damage response. Required for expression of numerous cell wall biosynthesis inhibitor caspofungin-responsive genes. Plays a key role in adherence, hyphal development, and virulence (By similarity) | Candidozyma auris (Yeast) (Candida auris) | 679 | Nucleus. Cytoplasm. Note=Localizes to the cytoplasm under basal conditions and translocates to the nucleus during caspofungin treatment | MENYLMSSPSQHHHPHQQPHQQHNPYANSDTLTNLPNLENDLDFSDSEVVPPSKDYQGSPNVYDGLDFSTDMATDFVYDSTLEFDLDDHKHMPDPAEMGHSKHFSVDRPLSAPFYLSQNSRTNFNHSRNISLDDTAYKRSFHKHSASLVSNAAEPPSGTFAHSHSSNTLQSSSDSMPQLSSSVSNPSLLDSPHSAMQTATPGRRHKSSSVSSHTNLYTTPLRGGTHVSPLTHTKVGKTPIGKTHRRNRSRASLEPSSAHLLATVANMKGTSNASNLALSSAQTPSGHLTASTSQHFHGINLSEANPFHNEFVSPGVGSGH... | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0031505",
"GO:0045229",
"GO:0071554",
"GO:0071555",
"GO:0071840",
"GO:0071852",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0031505",
"GO:0045229",
"GO:0071554",
"GO:0071555",
"GO:0071840",
"GO:0071852"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-A0A2H1A5W4-F1-model_v6.pdb | {"IPR036236": [631, 677], "IPR013087": [622, 675]} | - IPR013087: Zinc finger C2H2-type (domain) [622-675]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [631-677] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interactio... | |
Q5A1E3 | Transcriptional regulator CBF1 | Transcription factor that binds ribosomal protein gene promoters and rDNA locus with TBF1. Necessary for the expression of genes involved in assimilation of inorganic sulfate. Also required for the expression of respiratory genes and glycolytic genes. Does not bind to centromeres and is not necessary for efficient chro... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 251 | Nucleus | MVKSHKRTLEKDEEHQEKKKANKISKDDMEIDAELLTQQASDSAHTDTATAAVAAVNNEQGKELEQTESSTNQTSALDKDDKETKDNLNPREETQSSHQEIDIPKDQLTNQQNLADQHQQYQYHQQLAQTNFKTEPTNSAKPPHGSEEWHRQRRENHKEVERKRRESINTGIRELARLIPTTDTNKAQILQRAVEYIKRLKENENNNIEKWTLEKLLTEQAVSELSASNEKLKHELESAYREIEQLKRGKK | [
"GO:0000070",
"GO:0000096",
"GO:0000097",
"GO:0000103",
"GO:0000278",
"GO:0000280",
"GO:0000819",
"GO:0006082",
"GO:0006139",
"GO:0006351",
"GO:0006520",
"GO:0006555",
"GO:0006790",
"GO:0006996",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058"... | [
"GO:0000070",
"GO:0000096",
"GO:0000097",
"GO:0000103",
"GO:0000278",
"GO:0000280",
"GO:0000819",
"GO:0006082",
"GO:0006139",
"GO:0006351",
"GO:0006520",
"GO:0006555",
"GO:0006790",
"GO:0006996",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058"... | [
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003690",
"GO:0003700",
"GO:0005488",
"GO:0019237",
"GO:0043565",
"GO:0140110",
"GO:1990837"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q5A1E3-F1-model_v6.pdb | {"IPR036638": [143, 210], "IPR047206": [147, 233], "IPR011598": [152, 206]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [143-210]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [152-206]
- IPR047206: Centromere-binding protein 1-like, bHLHzip domain (domain) [147-233] | - Met28p
- Met4p
- Histone H3-like centromeric protein CSE4 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (... |
P31225 | Corticosteroid-binding protein | May be a flavoprotein with enzymatic activity | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 489 | MSRTKSTKVLIIGAGVSGLKAAETILSKSFLTGDDVLVVEAQNRIGGRLKTTDTSQSKLGINYDLGASWFHDSLNNIVLNHMINDGLLDDEKDVYFDDKDLKTFSSTGEVPIVDKKLNRVLEDIEKYIQLYFNRNLGVPDLSLRDIVAQYFEKYNRLITEEQREYCGRMMRYLEFWFGISWDRISGKYAVTTHQGRNLLNKKGYGYLVESLAKRIPESSLLLEEPVNKIIRNNKDAGKRVLVETINGLQIFCDYLIVTVPQSILSLEESSPYSIKWEPKLPQRLVESINSIHFGALGKVIFEFDRIFWDNSKDRFQIIAD... | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-P31225-F1-model_v6.pdb | {"IPR036188": [4, 475], "IPR050281": [7, 477], "IPR002937": [16, 474]} | - IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [4-475]
- IPR002937: Amine oxidase (domain) [16-474]
- IPR050281: Flavin monoamine oxidase and related enzymes (family) [7-477] | - Ornithine decarboxylase
- Spermidine synthase
- Aldehyde dehydrogenase domain-containing protein
- Aldehyde dehydrogenase
- Agmatinase
- Afp99p
- Spermine synthase
- Amine oxidase
- Amine oxidase
- Polyamine oxidase | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0005496 (steroid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0071704 (org... | |
Q8WUD4 | Coiled-coil domain-containing protein 12 | Homo sapiens (Human) | 166 | MEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q8WUD4-F1-model_v6.pdb | {"IPR013169": [1, 166]} | - IPR013169: mRNA splicing factor Cwf18-like (family) [1-166] | - Pre-mRNA-processing factor 17
- Crooked neck-like protein 1
- Pre-mRNA-processing factor 19
- Cell division cycle 5-like protein
- 116 kDa U5 small nuclear ribonucleoprotein component
- Pre-mRNA-splicing factor SYF2
- Peptidyl-prolyl cis-trans isomerase-like 1
- Transcription elongation regulator 1
- Serine/arginine ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | ||
Q59NH8 | Tyrosine-protein phosphatase CDC14 | Protein phosphatase which antagonizes mitotic cyclin- dependent kinase CDC28, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytoki... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 542 | Nucleus, nucleolus. Cytoplasm. Bud neck. Cytoplasm, cytoskeleton, spindle pole. Cell septum. Note=Does not accumulate in the nucleolus in interphase cells. At the G1-S transition, starts to accumulate both in the nucleolus and the and the DAPI-staining region of the nucleus. At the S-G2 transition, starts to concentrat... | MHSSSVHVPLIEFLKNRIYLGAYDHHKRDTEDLAYFTVEDALPYNAFYMDFGPLNIGHLYRFAVLLHKKLNEDSTQGKGLVIYSSTSPKERANLACLLCCYMILLQNWAPHQVLQPIAQITPPLQAFRDAGYSSADYEITIQDVVYAMWRAKERGMIDLAKFDLDEYEQYERVDQGDFNVISKDFIAFASPQQSKRGGLNEPFQKVLEYFVENNVQLVVRLNSHLYDAKEFTKRNIKHIDMIFDDGTCPTLEYVQKFIGAAECIINKGGKIAVHCKAGLGRTGCLIGAHLIYTHGFTANECIAYMRMIRPGMVVGPQQHW... | [
"GO:0000278",
"GO:0000920",
"GO:0001403",
"GO:0006950",
"GO:0007049",
"GO:0007096",
"GO:0007346",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010564",
"GO:0030447",
"GO:0030448",
"GO:0031667",
"GO:0031669",
"GO:0032954",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0042149"... | [
"GO:0000278",
"GO:0000920",
"GO:0001403",
"GO:0006950",
"GO:0007049",
"GO:0007096",
"GO:0007346",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010564",
"GO:0030447",
"GO:0030448",
"GO:0031667",
"GO:0031669",
"GO:0032954",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0042149"... | [
"GO:0003674",
"GO:0003824",
"GO:0004721",
"GO:0008138",
"GO:0016787",
"GO:0016788",
"GO:0016791",
"GO:0042578",
"GO:0140096"
] | [
"GO:0000935",
"GO:0000936",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005730",
"GO:0005815",
"GO:0005816",
"GO:0005856",
"GO:0015630",
"GO:0030428",
"GO:0031974",
"GO:0031981",
"GO:0032153",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232"... | AF-Q59NH8-F1-model_v6.pdb | {"IPR029021": [3, 336], "IPR050561": [36, 502], "IPR029260": [10, 152], "IPR044506": [161, 331], "IPR020422": [177, 334], "IPR000340": [201, 325], "IPR003595": [234, 328], "IPR000387": [255, 320], "IPR016130": [273, 283]} | - IPR044506: Dual-specificity phosphatase CDC14, C-terminal (domain) [161-331]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [234-328]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [273-283]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [255-320]
- IPR029021:... | - Cell cycle protein kinase DBF2
- Serine/threonine protein kinase
- Serine/threonine-protein kinase
- Ras family GTPase
- Oxidant-induced cell-cycle arrest protein 5
- separase
- Mob1p
- Mitosis inhibitor protein kinase SWE1
- Cdh1p
- Serine/threonine-protein kinase CBK1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrola... |
Q5ANA3 | Pleiotropic ABC efflux transporter of multiple drugs CDR1 | Pleiotropic ABC efflux transporter that confers resistance to numerous chemicals including anisomycin, cycloheximide, fluconazole, miconazole, ketoconazole, itriconazole, nystatin, terbinafine, amorolfine, brefeldin A, amphotericin B, fluphenazine, as well as estrogen. Plays a role in farnesol-induced apoptotic process... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,501 | Cell membrane; Multi-pass membrane protein. Note=Accumulates at membrane rafts. Both ergosterol and sphingolipids are essential for targeting to membrane rafts. Mislocalizes to the vacuole in absence of FZO1 | MSDSKMSSQDESKLEKAISQDSSSENHSINEYHGFDAHTSENIQNLARTFTHDSFKDDSSAGLLKYLTHMSEVPGVNPYEHEEINNDQLNPDSENFNAKFWVKNLRKLFESDPEYYKPSKLGIGYRNLRAYGVANDSDYQPTVTNALWKLATEGFRHFQKDDDSRYFDILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERHYRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSG... | [
"GO:0006810",
"GO:0006869",
"GO:0008150",
"GO:0009636",
"GO:0009987",
"GO:0010876",
"GO:0015748",
"GO:0015850",
"GO:0015903",
"GO:0015914",
"GO:0016043",
"GO:0033036",
"GO:0034204",
"GO:0042221",
"GO:0042908",
"GO:0045117",
"GO:0045332",
"GO:0046618",
"GO:0050896",
"GO:0051179"... | [
"GO:0006810",
"GO:0006869",
"GO:0008150",
"GO:0009636",
"GO:0009987",
"GO:0010876",
"GO:0015748",
"GO:0015850",
"GO:0015903",
"GO:0015914",
"GO:0016043",
"GO:0033036",
"GO:0034204",
"GO:0042221",
"GO:0042908",
"GO:0045117",
"GO:0045332",
"GO:0046618",
"GO:0050896",
"GO:0051179"... | [
"GO:0000166",
"GO:0003674",
"GO:0003824",
"GO:0005215",
"GO:0005319",
"GO:0005488",
"GO:0005496",
"GO:0005524",
"GO:0005548",
"GO:0008289",
"GO:0008525",
"GO:0015244",
"GO:0015247",
"GO:0015665",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0016887",
"GO:0017076"... | [
"GO:0005575",
"GO:0005576",
"GO:0005886",
"GO:0009986",
"GO:0016020",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-Q5ANA3-F1-model_v6.pdb | {"IPR027417": [154, 1100], "IPR005285": [94, 1492], "IPR029481": [45, 146], "IPR003439": [150, 1103], "IPR034001": [167, 386], "IPR003593": [179, 1079], "IPR013525": [496, 1392], "IPR010929": [716, 807], "IPR034003": [858, 1085], "IPR017871": [303, 317]} | - IPR034001: ATP-binding cassette transporter, PDR-like subfamily G, domain 1 (domain) [167-386]
- IPR010929: CDR ABC transporter (domain) [716-807]
- IPR029481: Pleiotropic ABC efflux transporter, N-terminal domain (domain) [45-146]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfami... | - Multidrug resistance protein 1
- Lanosterol 14-alpha demethylase
- Major facilitator superfamily multidrug transporter FLU1
- Transcription factor TAC1
- Sterol uptake control protein 2
- Delta(7)-sterol 5(6)-desaturase ERG3
- ATP-binding cassette transporter
- Sphingoid long-chain base transporter RSB1
- MFS antipor... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0140326 (ATPase-coupled intramembrane lipid transporter activity), GO:0005319 (lipid transporter activity), GO:0140303 (intramembrane lipid transporter activity), GO:0005548 (phospholipid... |
Q9C0B2 | Cilia- and flagella-associated protein 74 | As part of the central apparatus of the cilium axoneme may play a role in cilium movement. May play an important role in sperm architecture and function | Homo sapiens (Human) | 1,584 | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme | MEDDGSLLPEDELLADALLLEDERDELEDPEFDIKCLLQEAEDDVDPGHSSSVKELDTDADKLKKKTAEDRTQAFHLRQNLSALDKMHEEQELFTEKMRGELRACRQRRDLIDKQQEAVAAEIATEEEAGNMAAVGRLQAVSRRLFAELENERDLQSRTEAVLKESENTMWHIEIQEGRLEAFRTADREEVEATGRRLQVRAAEQLCREQEALGKVERNRLLRIRKSLNTQKELGLRHQKLLEDARKNHKVAVRFLKASLGRIREQEKKEEMECHEYMRRRMDAVVALKGSISANRDTLRKFQAWDRAKAELAEQRVQAE... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0097729",
"GO:0110165",
"GO:0120025"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0097729",
"GO:0110165",
"GO:0120025"
] | AF-Q9C0B2-F1-model_v6.pdb | {"IPR013783": [611, 1477], "IPR056306": [618, 800], "IPR056307": [802, 914], "IPR056310": [920, 1014]} | - IPR013783: Immunoglobulin-like fold (homologous_superfamily) [611-1477]
- IPR056306: CFAP74, second Ig-like domain (domain) [618-800]
- IPR056307: CFAP74, third Ig-like domain (domain) [802-914]
- IPR056310: CFAP74, fourth Ig-like domain (domain) [920-1014] | - Leucine-rich repeat and guanylate kinase domain-containing protein
- Gamma-aminobutyric acid receptor subunit delta
- Cilia- and flagella-associated protein 221 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental proc... |
Q96SZ6 | Mitochondrial tRNA methylthiotransferase CDK5RAP1 | Methylthiotransferase that catalyzes the conversion of N6- (dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp). Essential for efficient and highly accurate... | Homo sapiens (Human) | 601 | Mitochondrion | MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLAAGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQVFLPPRPPKVLGLQGLKEVTLLGQNVNS... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0035596",
"GO:0035597",
"GO:0050497",
"GO:0140098",
"GO:0140101",
"GO:0140640",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005739",
"GO:0005759",
"GO:0005829",
"GO:0031974",
"GO:0031981"... | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0035596",
"GO:0035597",
"GO:0050497",
"GO:0140098",
"GO:0140101",
"GO:0140640"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005739",
"GO:0005759",
"GO:0005829",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q96SZ6-F1-model_v6.pdb | {"IPR038135": [100, 234], "IPR058240": [245, 508], "IPR023404": [246, 518], "IPR005839": [98, 594], "IPR006463": [98, 591], "IPR007197": [98, 594], "IPR013848": [100, 220], "IPR006638": [248, 501], "IPR002792": [515, 590], "IPR020612": [252, 272]} | - IPR006463: tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB (family) [98-591]
- IPR038135: Methylthiotransferase, N-terminal domain superfamily (homologous_superfamily) [100-234]
- IPR005839: Methylthiotransferase (family) [98-594]
- IPR058240: Radical SAM superfamily (homologous_superfamily) [245-508]
- I... | - Exosome complex component RRP40
- Exosome complex component RRP46
- Cyclin-dependent kinase 5
- tRNA dimethylallyltransferase
- Cyclin-dependent kinase 5 activator 1
- Pre-mRNA-processing factor 40 homolog B | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0051540 (metal cluster binding), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0051536 (iron-sulfur cluster binding), GO:0051539 (4 iron,... |
Q8GX93 | Chloride channel protein CLC-e | Voltage-gated thylakoid chloride (Cl) channel/transporter involved in chloride homeostasis after transition from light to dark. Influences chloroplast ultrastructure and subsequent photosynthetic electron transport. During photosynthetic response on transition from dark to low light, involved in a sequential mechanism ... | Arabidopsis thaliana (Mouse-ear cress) | 710 | Membrane; Multi-pass membrane protein | MAATLPLCAALRSPVSSRRFAPIHKTDVPFQFNVVLSPFFGSVAIGGRIFPRLPAAKQETDQDEVGFDQQPSQELAIASACLVGVLTGVSVVLFNNCVHLLRDFSWDGIPDRGASWLREAPIGSNWLRVILVPTIGGLVVSILNQLRESAGKSTGDSHSSLDRVKAVLRPFLKTVAACVTLGTGNSLGPEGPSVEIGASIAKGVNSLFNKSPQTGFSLLAAGSAAGISSGFNAAVAGCFFAVESVLWPSSSTDSSTSLPNTTSMVILSAVTASVVSEIGLGSEPAFKVPDYDFRSPGELPLYLLLGALCGLVSLALSRCT... | [
"GO:0006810",
"GO:0006811",
"GO:0006820",
"GO:0006821",
"GO:0006996",
"GO:0008150",
"GO:0009657",
"GO:0009668",
"GO:0009987",
"GO:0010027",
"GO:0010109",
"GO:0015698",
"GO:0016043",
"GO:0019222",
"GO:0034220",
"GO:0042548",
"GO:0043467",
"GO:0050789",
"GO:0050794",
"GO:0051179"... | [
"GO:0006810",
"GO:0006811",
"GO:0006820",
"GO:0006821",
"GO:0006996",
"GO:0008150",
"GO:0009657",
"GO:0009668",
"GO:0009987",
"GO:0010027",
"GO:0010109",
"GO:0015698",
"GO:0016043",
"GO:0019222",
"GO:0034220",
"GO:0042548",
"GO:0043467",
"GO:0050789",
"GO:0050794",
"GO:0051179"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0009507",
"GO:0009526",
"GO:0009534",
"GO:0009535",
"GO:0009536",
"GO:0009579",
"GO:0016020",
"GO:0019867",
"GO:0031090",
"GO:0031967",
"GO:0031968",
"GO:0031976",
"GO:0034357",
"GO:0042170",
"GO:0042651",
"GO:0043226",
"GO:0043227",
"GO:0043228"... | AF-Q8GX93-F1-model_v6.pdb | {"IPR014743": [76, 499], "IPR046342": [557, 702], "IPR050368": [68, 699], "IPR001807": [143, 497], "IPR000644": [561, 696]} | - IPR050368: Voltage-gated ClC-type chloride channel (family) [68-699]
- IPR046342: CBS domain superfamily (homologous_superfamily) [557-702]
- IPR014743: Chloride channel, core (homologous_superfamily) [76-499]
- IPR000644: CBS domain (domain) [561-696]
- IPR001807: Chloride channel (family) [143-497] | - Chloride channel protein CLC-d
- Chloride channel protein CLC-c
- Chloride channel protein CLC-b
- Putative chloride channel-like protein CLC-g
- Chloride channel protein CLC-a
- K(+) efflux antiporter 3, chloroplastic
- Two-pore potassium channel 3
- Voltage-dependent chloride channel 1, chloroplastic
- Putative DUF... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0003676 (nucleic acid binding), GO:0016772 (transferase activity, transferring ... |
Q20754 | Cuticle collagen 38 | Probable cuticular collagen-like protein (Probable). Nematode cuticles are composed largely of collagen-like proteins (Probable). The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable). Acts downstream of the Wnt signaling pathway, perhaps in the formation of t... | Caenorhabditis elegans | 287 | Nucleus | MSKYLVPVCASISLVAVFGALVAMHSIVVDIDTMREEIVTGVHDMKVMSDDAWNRMIGFTKPSLDSESRSAAFASVFRNKRSAYPSQCNCDANSQGCPPGPPGPPGLPGGRGDQGPSGDKGRDGASGVSLAVTHHLPGGCIQCPQGPPGETGPDGDIGEPGFPGASGSAGQCGEDGAPGEAGITGEQGPQGEPGTEGSEGPTGQDGTIGGPGLPGQPGTPGWPGSQGEPGKNGDSGVDGEQGPQGPQGPDGQPGRDADNGQPGLPGKDGSIGPDANYCPCPARAKKH | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-Q20754-F1-model_v6.pdb | {"IPR002486": [4, 56], "IPR008160": [215, 273]} | - IPR008160: Collagen triple helix repeat (repeat) [215-273]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [4-56] | - Nematode cuticle collagen N-terminal domain-containing protein
- Cuticle collagen 49
- Nematode cuticle collagen N-terminal domain-containing protein
- Protein dao-4
- Cuticle collagen 71
- Nematode Specific Peptide family
- DUF229 domain-containing protein
- COLlagen
- Venom protein
- Major sperm protein | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0042302 (structural constituent of cuticle)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structur... |
O44989 | Cuticle collagen 49 | Probable cuticular collagen-like protein (Probable). Nematode cuticles are composed largely of collagen-like proteins (Probable). The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable). Acts downstream of the Wnt signaling pathway, perhaps in the formation of t... | Caenorhabditis elegans | 283 | MWKFVIGSVSTAAFFVSVCTIYFSVSMLDELDSFRLSIRDELEDWKEVSDDTWQRLNDMTSRNVPKKTNILKEFVRGKRNVGNDQCNCAEPTKNCPAGPPGEKGSLGNPGQPGPDGVDGDNGVDGDVVIHDMPNPKECIKCPAGPPGPPGPPGPLGPRGDKGPSGPRGALGDQGETGPVGEIGDQGPPGSAGRAGPRGQAGQPGTIAIVGLAGRPGPQGPLGEPGAQGEPGVDGKDGALGAPGRKAENGRPGKRGKDGVAGVPGTRGKEGEDAGYCTCPPRTA | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-O44989-F1-model_v6.pdb | {"IPR002486": [3, 56], "IPR008160": [213, 271]} | - IPR008160: Collagen triple helix repeat (repeat) [213-271]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [3-56] | - Cuticle collagen 71
- Nematode cuticle collagen N-terminal domain-containing protein
- Cuticle collagen 38
- Protein dao-4
- CPG4 domain-containing protein
- Nematode cuticle collagen N-terminal domain-containing protein
- Nematode cuticle collagen N-terminal domain-containing protein
- COLlagen
- Venom protein
- Nem... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0042302 (structural constituent of cuticle)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structur... | |
Q9N4U2 | Cuticle collagen 71 | Probable cuticular collagen-like protein (Probable). Nematode cuticles are composed largely of collagen-like proteins (Probable). The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable). Acts downstream of the Wnt signaling pathway, perhaps in the formation of t... | Caenorhabditis elegans | 371 | Membrane; Single-pass membrane protein. Nucleus | MRNAGGDKPFSTPVLLREMGLKTHVDDDPKTKAYRLIGYAAVTFSTVSVICFCVTMPVVFTYVQSVKRQMSHEMATCNVNARQIFDDVAALRAGFPFAQAGNRTARQAGYDVHPSKPTPVGYSGGDAAAAEVKGNSPAAAYEDKPFVAVGVEEGPHTATTGSDSEGTCHDCCLPGPPGPPGPPGRPGPNGKAGANGLNGNPGRPPEAPCEPVTPPPCPPCPAGPKGAPGQAGYPGADGQPGSQGDNGEKGSDGAAGEKGRPGPLGKIGEPGATGETGENAENSEPTPGPQGPPGAIGPVGSRGTPGHPGEDGEAGAPGAP... | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-Q9N4U2-F1-model_v6.pdb | {"IPR002486": [36, 88], "IPR008160": [223, 281]} | - IPR008160: Collagen triple helix repeat (repeat) [223-281]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [36-88] | - Cuticle collagen 49
- Nematode cuticle collagen N-terminal domain-containing protein
- Protein dao-4
- Cuticle collagen 38
- Prion-like-(Q/N-rich)-domain-bearing protein
- CPG4 domain-containing protein
- Nematode cuticle collagen N-terminal domain-containing protein
- Nematode Specific Peptide family
- Venom protein... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellul... |
P21334 | Phytoene desaturase | Phytoene desaturase involved in the carotenoid biosynthesis pathway. Converts phytoene into 3,4-didehydrolycopene via the intermediates phytofluene, zeta-carotene, neurosporene and lycopene, by introducing up to five double bonds into phytoene. Is also able to desaturate 1-hydroxyneurosporene into 1-hydroxylycopene and... | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / | 595 | Membrane; Single-pass membrane protein | MAETQRPRSAIIVGAGAGGIAVAARLAKAGVDVTVLEKNDFTGGRCSLIHTKAGYRFDQGPSLLLLPGLFRETFEDLGTTLEQEDVELLQCFPNYNIWFSDGKRFSPTTDNATMKVEIEKWEGPDGFRRYLSWLAEGHQHYETSLRHVLHRNFKSILELADPRLVVTLLMALHPFESIWHRAGRYFKTDRMQRVFTFATMYMGMSPFDAPATYSLLQYSELAEGIWYPRGGFHKVLDALVKIGERMGVKYRLNTGVSQVLTDGGKNGKKPKATGVQLENGEVLNADLVVVNADLVYTYNNLLPKEIGGIKKYANKLNNRK... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148",
"GO:0003674",
"GO:0003824",
"GO:0016166",
"GO:0016491"... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148"
] | [
"GO:0003674",
"GO:0003824",
"GO:0016166",
"GO:0016491",
"GO:0016627"
] | [] | AF-P21334-F1-model_v6.pdb | {"IPR036188": [6, 511], "IPR014105": [10, 518], "IPR002937": [18, 294], "IPR008150": [481, 501]} | - IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [6-511]
- IPR008150: Phytoene dehydrogenase, bacterial-type, conserved site (conserved_site) [481-501]
- IPR014105: Carotenoid/retinoid oxidoreductase (family) [10-518]
- IPR002937: Amine oxidase (domain) [18-294] | - Bifunctional lycopene cyclase/phytoene synthase
- Probable squalene synthase
- Geranylgeranyl pyrophosphate synthase
- Squalene/phytoene synthase
- Imidazole glycerol phosphate synthase hisHF
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- Carotenoid dioxygenase
- 4-hydroxybenzoate polyprenyltransferase, mitochon... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular proces... |
I1MRZ6 | Diacylglycerol O-acyltransferase 3-2 | Involved in triacylglycerol (TAG) biosynthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. Incorporates preferentially monounsaturated fatty acids (MUFAs), especially oleic acid (C18:1) and to some extent palmitoleic acid (C16:1), into TAGs accumulating in seeds oil. Can ... | Glycine max (Soybean) (Glycine hispida) | 338 | Cytoplasm | MEISGTVLRQVSYVSGYGTHTRSRGLAPRFGVRMGMGSGFCDEGHLRYYQDTKKVLTPKKKLKLLKGFSKLGLASDPEKLAMFYDLQQNLTSDAGDVLLRELEAARAKEKEVKKKRKQEKKAKLKAAKMNCESSSSSSSESSDSDCGCDQVVDMNTFRAGVGVGVGVGVGVVAPAPVEESPLPKTAPIVEDANAHCVAMELCSKNDIYVSSASNGFKNESAVVTSAPQKRIEVCMGNKCKRSGAAALMQEFEKVVGVEGVAVVACKCMGKCKTAPNVKVQNSVDHNSLAQGLDDSVKIPANPLCIGVGLEDVDAIVARYF... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486",
"GO:0003674",
"GO:0003824",
"GO:0004144",
"GO:0008374",
"GO:0016411"... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004144",
"GO:0008374",
"GO:0016411",
"GO:0016740",
"GO:0016746",
"GO:0016747"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | AF-I1MRZ6-F1-model_v6.pdb | {"IPR036249": [226, 285]} | - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [226-285] | - Diacylglycerol O-acyltransferase 1B
- Acyltransferase
- Diacylglycerol O-acyltransferase 2D
- Acyltransferase
- Acyltransferase
- Diacylglycerol O-acyltransferase 3-1
- diacylglycerol O-acyltransferase
- Diacylglycerol O-acyltransferase 1A | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016740 (transferase activity), GO:0043169 (cation binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acy... |
Q6PAC3 | DDB1- and CUL4-associated factor 13 | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, m... | Mus musculus (Mouse) | 445 | Nucleus, nucleolus. Note=In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component | MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPKSLASVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGMCTRFCGTSFFTVGDDKTVKQWKMDGPGYGEEEEPLYTVLGKTVYTGIDHHWKDPVFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPVETFLLGSCASDRNIVLYDMRQATPLKKVILEMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVY... | [
"GO:0001555",
"GO:0001890",
"GO:0001893",
"GO:0003006",
"GO:0006139",
"GO:0006364",
"GO:0006396",
"GO:0007276",
"GO:0007281",
"GO:0007292",
"GO:0007565",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009888",
"GO:0009987",
"GO:0009994",
"GO:0010467",
"GO:0016049"... | [
"GO:0001555",
"GO:0001890",
"GO:0001893",
"GO:0003006",
"GO:0006139",
"GO:0006364",
"GO:0006396",
"GO:0007276",
"GO:0007281",
"GO:0007292",
"GO:0007565",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009888",
"GO:0009987",
"GO:0009994",
"GO:0010467",
"GO:0016049"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0030674",
"GO:0060090",
"GO:0140767",
"GO:1990756"
] | [
"GO:0000151",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005730",
"GO:0031461",
"GO:0031974",
"GO:0031981",
"GO:0032991",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0043233",
"GO:0070013",
"GO:0080008",
"GO:0110165",
"GO:0140535"... | AF-Q6PAC3-F1-model_v6.pdb | {"IPR036322": [12, 353], "IPR015943": [39, 391], "IPR051733": [1, 444], "IPR007287": [354, 440], "IPR019775": [82, 96], "IPR001680": [55, 362]} | - IPR051733: WD repeat-containing DCAF13/WDSOF1 (family) [1-444]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [12-353]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [39-391]
- IPR001680: WD40 repeat (repeat) [55-362]
- IPR019775: WD40 repeat... | - WD repeat-containing protein 46
- Nucleolar complex protein 4 homolog
- WD repeat domain 36
- U3 small nucleolar RNA-associated protein 4 homolog
- Transducin beta-like protein 3
- Bystin
- WD repeat-containing protein 43
- U3 small nucleolar RNA-interacting protein 2
- KRR1 small subunit processome component homolog... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimul... |
Q7L014 | Probable ATP-dependent RNA helicase DDX46 | Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the s... | Homo sapiens (Human) | 1,031 | Nucleus speckle. Nucleus, Cajal body. Note=Present in Cajal bodies (CBs) and nuclear speckles | MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEP... | [
"GO:0000245",
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0016070",
"GO:0016071",
"GO:0022607",
"GO:0022613",
"GO:0022618"... | [
"GO:0000245",
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0016070",
"GO:0016071",
"GO:0022607",
"GO:0022613",
"GO:0022618"... | [] | [] | AF-Q7L014-F1-model_v6.pdb | {"IPR027417": [300, 757], "IPR014014": [372, 400], "IPR014001": [391, 596], "IPR011545": [396, 568], "IPR001650": [592, 753], "IPR056149": [933, 1012], "IPR000629": [527, 535]} | - IPR011545: DEAD/DEAH-box helicase domain (domain) [396-568]
- IPR001650: Helicase, C-terminal domain-like (domain) [592-753]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [372-400]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [300-757]
- IPR014001: Helicase su... | - Splicing factor 3B subunit 1
- Splicing factor 3A subunit 3
- Splicing factor 3A subunit 2
- Splicing factor 3A subunit 1
- Splicing factor 3B subunit 5
- Splicing factor 3B subunit 2
- Splicing factor 3B subunit 3
- Small nuclear ribonucleoprotein Sm D1
- U2 small nuclear ribonucleoprotein A'
- PHD finger-like domai... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0004386 (helicase activity), GO:0008186 (ATP-dependent activit... |
F1QLP1 | 11-beta-hydroxysteroid dehydrogenase type 2 | Catalyzes the conversion of biologically active 11beta- hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortisol, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as cortisone, in the presence of NAD(+). Cortisol is the primary glucocorticoid in teleosts and is released to increase glucose bioavailability... | Danio rerio (Zebrafish) (Brachydanio rerio) | 414 | Membrane; Multi-pass membrane protein | MEDFAVSFWIYIGVMSIFVGGAVKKFLAFNIGAMPSVVVWLGATLLVERLCALCMPAVLARLVLCVCCWLYFTWATPKPSLPVEDKAVFITGCDSGFGNATAKKLDAMGFEVFATVLNLEGEGAKHLRKVCSSRLTLLQVDITQPQQVQQALLDTKAKLGIRDLWGLVNNAGWCVNIGDAELSLMSNYRGCMEVNFFGTVTVTRTFLPLLRQSKGRIVTISSPSGEHPFPCLASYGASKAALNLFINTLRHELDPWGVKVSTILPSAYKTGQSSNAEYWEKQYKSLLQGLSPNLLEEYGEEYLLETKELFQNYAKTANED... | [
"GO:0003674",
"GO:0003824",
"GO:0016229",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0033764",
"GO:0070523"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016229",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0033764",
"GO:0070523"
] | [] | AF-F1QLP1-F1-model_v6.pdb | {"IPR036291": [80, 373], "IPR002347": [86, 277], "IPR020904": [222, 250]} | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [80-373]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [222-250]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [86-277] | - Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Hydroxysteroid 11-beta-dehydrogenase 1-like protein
- Hydroxysteroid (11-beta) dehydrogenase 1-like b
- 17-beta-hydroxysteroid dehydrogenase type 3
- Mineralocorticoid receptor
- Aromatase
- Cytochrome P450, family 17, subfamily A, polypep... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016229 (steroid dehydrogenase activity), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, N... |
Q9Y2G8 | DnaJ homolog subfamily C member 16 | Plays an important role in regulating the size of autophagosomes during the formation process | Homo sapiens (Human) | 782 | Endoplasmic reticulum membrane; Single-pass type IV membrane protein | MEVRKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELEELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVGLRGTEEMTRRYNIN... | [
"GO:0006914",
"GO:0006996",
"GO:0007033",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0016043",
"GO:0016236",
"GO:0016243",
"GO:0032535",
"GO:0061919",
"GO:0065007",
"GO:0065008",
"GO:0071840",
"GO:0090066",
"GO:1905037",
"GO:0005575",
"GO:0005622",
"GO:0005737"... | [
"GO:0006914",
"GO:0006996",
"GO:0007033",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0016043",
"GO:0016236",
"GO:0016243",
"GO:0032535",
"GO:0061919",
"GO:0065007",
"GO:0065008",
"GO:0071840",
"GO:0090066",
"GO:1905037"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | AF-Q9Y2G8-F1-model_v6.pdb | {"IPR036869": [27, 137], "IPR036249": [146, 247], "IPR052448": [1, 741], "IPR001623": [28, 104], "IPR013766": [119, 247], "IPR043361": [136, 245], "IPR018253": [70, 89]} | - IPR013766: Thioredoxin domain (domain) [119-247]
- IPR043361: DnaJ homolog subfamily C member 16, TRX domain (domain) [136-245]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [146-247]
- IPR018253: DnaJ domain, conserved site (conserved_site) [70-89]
- IPR052448: DnaJ Homolog Subfamily C Member 16... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulatio... | |
Q59Z14 | Deoxyhypusine hydroxylase | Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 318 | Cytoplasm. Nucleus | MSADEVNIDTASLEELRDILINKTGNTKLANRFRALFNLKSVGSEDSDKERAHKAIKYIAECFNDDSELLKHEVAYVLGQTKDLYAAPYLREVLENDNQQCMVRHEAAEALGALGDKESLPLLEKYFKEDPLLEIRQTCELAIERIHWENSEKAKNEVLEKSLYTSIDPAPPLATNDSTSKVEKLKEILNDQDKPLFERYRAMFRLRDIGTDEACLALASGFDDPSALFKHEIAYVFGQMCNPVTVPSLIKVLKDESEAGMVRHEAAEALGSIATDECLPVLQSFLNDSEPVVRDSAIVALDMYEYENSNELEYATVK | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-Q59Z14-F1-model_v6.pdb | {"IPR011989": [9, 313], "IPR016024": [68, 302], "IPR027517": [13, 313], "IPR004155": [68, 289], "IPR021133": [245, 285]} | - IPR004155: PBS lyase HEAT-like repeat (repeat) [68-289]
- IPR016024: Armadillo-type fold (homologous_superfamily) [68-302]
- IPR011989: Armadillo-like helical (homologous_superfamily) [9-313]
- IPR021133: HEAT, type 2 (repeat) [245-285]
- IPR027517: Deoxyhypusine hydroxylase (family) [13-313] | - Eukaryotic translation initiation factor 5A
- Deoxyhypusine synthase
- Elf1p
- Ribosome biosynthesis protein
- Elongation factor 3
- malate dehydrogenase (oxaloacetate-decarboxylating) | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on p... |
P0DPQ6 | DDIT3 upstream open reading frame protein | [Isoform AltDDIT3]: Product of the upstream open reading frame (uORF) of DDIT3/CHOP that is specifically produced in absence of stress, thereby preventing translation of downstream stress effector DDIT3/CHOP | Homo sapiens (Human) | 34 | Nucleus. Cytoplasm | MLKMSGWQRQSQNQSWNLRRECSRRKCIFIHHHT | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-P0DPQ6-F1-model_v6.pdb | NaN | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (re... | ||
Q78T81 | Early estrogen-induced gene 1 protein | Key component of TNFSF11/RANKL- and TNF-induced osteoclastogenesis pathways, thereby mediates bone resorption in pathological bone loss conditions. Required for TNFSF11/RANKL-induced osteoclastogenesis via its interaction with TNFRSF11A/RANK, thereby facilitates the downsteam transcription of NFATC1 and activation of P... | Mus musculus (Mouse) | 392 | Nucleus. Cytoplasm. Membrane raft | MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVRKELKGGKAYSKLGFTDLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTPPSTAKSISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKTRPTILGSGLPEEPDQSLSSPEEVFHSGHSRNSSYASQQSKLSGYSTEHSRSSSLSDLTHRRNTSTSSSASGGLSMAVEGPEGMEREHRPSEKPPRPPEKPPRPPRPLHLSDRSFRRKKDSV... | [
"GO:0002682",
"GO:0002684",
"GO:0002761",
"GO:0002763",
"GO:0008150",
"GO:0010720",
"GO:0045595",
"GO:0045597",
"GO:0045637",
"GO:0045639",
"GO:0045670",
"GO:0045672",
"GO:0048518",
"GO:0048522",
"GO:0050789",
"GO:0050793",
"GO:0050794",
"GO:0051094",
"GO:0051239",
"GO:0051240"... | [
"GO:0002682",
"GO:0002684",
"GO:0002761",
"GO:0002763",
"GO:0008150",
"GO:0010720",
"GO:0045595",
"GO:0045597",
"GO:0045637",
"GO:0045639",
"GO:0045670",
"GO:0045672",
"GO:0048518",
"GO:0048522",
"GO:0050789",
"GO:0050793",
"GO:0050794",
"GO:0051094",
"GO:0051239",
"GO:0051240"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0016020",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0045121",
"GO:0098857",
"GO:0110165"
] | AF-Q78T81-F1-model_v6.pdb | {"IPR039931": [1, 391], "IPR019448": [2, 152]} | - IPR039931: EEIG1/2-like (family) [1-391]
- IPR019448: NT-type C2 domain (domain) [2-152] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051179 (localization), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization),... | |
P25997 | Elongation factor 3 | Ribosome-dependent ATPase that functions in cytoplasmic translation elongation (By similarity). Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (By similarity). Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has red... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,050 | Cytoplasm | MSAASESKYSTEVLSELLSKLQVADNKDEAASNISTFLNSSIVEHDVPVEFFEDLKKQIQSKDAKVSLAALDAYKHIASTNGLSPSVEPYVVDLVSEVAVKAGDKNKDVQTAASDALLAIASAITPTAVKAILPKLIDNLTNTNKWTEKVAILRAVSQLVDTAKAQIALRMPELIPVLSESMWDTKKEVKEAATATMTKSTETIDNKDIEKFIPQLISCIAKPTEVPETVHLLGATTFVSEVTMATLSIMAPLLSRGLAERDTAIKRKAAVIVDNMCKLVEDPQIVAPFMDKLLPGLKNNFANMADPEAREVTQRALNTL... | [
"GO:0006412",
"GO:0006414",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0160307",
"GO:0003674",
"GO:0003746",
"GO:0003824",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0016887"... | [
"GO:0006412",
"GO:0006414",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0160307"
] | [
"GO:0003674",
"GO:0003746",
"GO:0003824",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0016887",
"GO:0017111",
"GO:0140657",
"GO:0180051"
] | [
"GO:0005575",
"GO:0005618",
"GO:0005886",
"GO:0009277",
"GO:0009986",
"GO:0016020",
"GO:0030312",
"GO:0030445",
"GO:0071944",
"GO:0110165"
] | AF-P25997-F1-model_v6.pdb | {"IPR011989": [2, 331], "IPR016024": [29, 1041], "IPR047036": [332, 421], "IPR027417": [423, 980], "IPR047038": [767, 876], "IPR050611": [649, 980], "IPR040533": [339, 414], "IPR003439": [429, 998], "IPR003593": [458, 975], "IPR015688": [799, 866], "IPR017871": [549, 916], "IPR021133": [174, 212]} | - IPR047036: Elongation factor 3, four helical bundle domain superfamily (homologous_superfamily) [332-421]
- IPR016024: Armadillo-type fold (homologous_superfamily) [29-1041]
- IPR011989: Armadillo-like helical (homologous_superfamily) [2-331]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologou... | - Elf1p
- Large ribosomal subunit protein uL18
- Cam1-1p
- Translation elongation factor EF1B gamma
- Tef4p
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein uS3 | Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0097159 (organic cyclic compound binding), GO:0090079 (translation regulator activit... |
Q59X67 | Enhanced filamentous growth protein 1 | Transcriptional regulator of the switch between 2 heritable states, the white and opaque states. These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence. Each state is heritable for many generations, and switching between states occurs stochastically, at low frequen... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 550 | Nucleus | MSTYSIPYYNQMNGNYNNGMPQQTTAANQQAFPQQQQPTTTGNASQQQQQAAATAAAAAVQQPYNYMFYQQQGQPGQQTGQTAGQQQQQQQQQQQYDYNTYNRYQYPAATSQGNYYQQTIPNQLSQPQPQHYNGSNRNYTSAPSGAPIPSNSTSGPSQQPPLPGQQAVPIPPHVSTMQQPTPVQDTLNASSTSTVGQFQPPGIRPRVTTTMWEDEKTLCYQVDANNVSVVRRADNNMINGTKLLNVAQMTRGRRDGILKSEKVRHVVKIGSMHLKGVWIPFERALAMAQREQIVDMLYPLFVRDIKRVIQTGVTPNAAAA... | [
"GO:0000122",
"GO:0000128",
"GO:0000902",
"GO:0001410",
"GO:0001558",
"GO:0002831",
"GO:0002833",
"GO:0003006",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0007124",
"GO:0007155",
"GO:0007584",
"GO:0007618",
"GO:0008150",
"GO:0009267",
"GO:0009268",
"GO:0009605",
"GO:0009607"... | [
"GO:0000122",
"GO:0000128",
"GO:0000902",
"GO:0001410",
"GO:0001558",
"GO:0002831",
"GO:0002833",
"GO:0003006",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0007124",
"GO:0007155",
"GO:0007584",
"GO:0007618",
"GO:0008150",
"GO:0009267",
"GO:0009268",
"GO:0009605",
"GO:0009607"... | [
"GO:0001216",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005694",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0110165"
] | AF-Q59X67-F1-model_v6.pdb | {"IPR036887": [206, 333], "IPR029790": [1, 543], "IPR003163": [206, 312], "IPR018004": [225, 311]} | - IPR036887: HTH APSES-type DNA-binding domain superfamily (homologous_superfamily) [206-333]
- IPR029790: EFG1/Phd1/StuA family (family) [1-543]
- IPR018004: KilA/APSES-type HTH, DNA-binding (domain) [225-311]
- IPR003163: Transcription regulator HTH, APSES-type DNA-binding domain (domain) [206-312] | - cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- Transcriptional regulator of filamentous growth FLO8
- Transcription activator TEC1
- Zinc cluster transcription factor CZF1
- Transcriptional regulator NRG1
- Transcriptional regulator EFH1
- Transcriptional repressor TUP1
- Transcriptional repressor TU... | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789... |
Q6PC64 | Very long chain fatty acid elongase 6 | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates... | Danio rerio (Zebrafish) (Brachydanio rerio) | 266 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MSVLALQEYEFERQFNEDEAIRWMQENWKKSFLFSALYAACILGGRHVMKQREKFELRKPLVLWSLTLAAFSIFGAIRTGGYMVNILMTKGLKQSVCDQSFYNGPVSKFWAYAFVLSKAPELGDTLFIVLRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYLVHAVMYSYYALRAAGFKISRKFAMFITLTQITQMVMGCVVNYLVYLWMQQGQECPSHVQNIVWSSLMYLSYFVLFCQFFFEAYITKRKSNAAKKSQ | [
"GO:0006082",
"GO:0006629",
"GO:0006631",
"GO:0006633",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0030497",
"GO:0032787",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046394",
"GO:0072330"
] | [
"GO:0006082",
"GO:0006629",
"GO:0006631",
"GO:0006633",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0030497",
"GO:0032787",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046394",
"GO:0072330"
] | [] | [] | AF-Q6PC64-F1-model_v6.pdb | {"IPR033675": [1, 266], "IPR002076": [14, 260], "IPR030457": [135, 143]} | - IPR002076: ELO family (family) [14-260]
- IPR030457: ELO family, conserved site (conserved_site) [135-143]
- IPR033675: Elongation of very long chain fatty acids protein 6 (family) [1-266] | - Elongation of very long chain fatty acids protein 5
- 3-oxoacyl-[acyl-carrier-protein] synthase
- Fatty acid synthase
- Acyl-CoA 6-desaturase
- Very-long-chain 3-oxoacyl-CoA reductase-B
- Very-long-chain 3-oxoacyl-CoA reductase-A
- 20beta-hydroxysteroid dehydrogenase type 2
- stearoyl-CoA 9-desaturase | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0004312 (fatty acid synthase activity), GO:0009922 (fatty acid ... |
P0A6C1 | Endonuclease 4 | Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin | Escherichia coli (strain K12) | 285 | MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-P0A6C1-F1-model_v6.pdb | {"IPR036237": [1, 277], "IPR001719": [1, 282], "IPR013022": [20, 277], "IPR018246": [69, 231]} | - IPR013022: Xylose isomerase-like, TIM barrel domain (domain) [20-277]
- IPR001719: AP endonuclease 2 (family) [1-282]
- IPR018246: AP endonuclease 2, zinc binding site (binding_site) [69-231]
- IPR036237: Xylose isomerase-like superfamily (homologous_superfamily) [1-277] | - Exodeoxyribonuclease III
- Endonuclease III
- Endonuclease III
- Uncharacterized sugar kinase YeiI
- Formamidopyrimidine-DNA glycosylase
- Superoxide dismutase [Mn]
- UvrABC system protein A
- Uracil-DNA glycosylase
- Adenine DNA glycosylase
- Endonuclease V | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0043167 (ion binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0043169 (cation binding), GO:0... | |
Q6UWW8 | Carboxylesterase 3 | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]- carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics | Homo sapiens (Human) | 571 | Endoplasmic reticulum lumen | MERAVRVESGVLVGVVCLLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSRFVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKKLKNTIYPLTVDGTV... | [
"GO:0003674",
"GO:0003824",
"GO:0016787",
"GO:0016788",
"GO:0052689"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016787",
"GO:0016788",
"GO:0052689"
] | [] | AF-Q6UWW8-F1-model_v6.pdb | {"IPR029058": [30, 563], "IPR050309": [26, 554], "IPR002018": [33, 547], "IPR019826": [216, 231]} | - IPR002018: Carboxylesterase, type B (domain) [33-547]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [30-563]
- IPR050309: Type-B Carboxylesterase/Lipase (family) [26-554]
- IPR019826: Carboxylesterase type B, active site (active_site) [216-231] | - S-formylglutathione hydrolase
- Hormone-sensitive lipase
- Tumor necrosis factor receptor superfamily member 13C | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), G... |
Q70Z53 | Protein FRA10AC1 | May be involved in pre-mRNA splicing | Homo sapiens (Human) | 315 | Nucleus | MHGHGGYDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRFHLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMTWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQDLFL | [
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016070",
"GO:0016071",
"GO:0032774",
"GO:0034654",
"GO:0043170",
"GO:0044238",
"GO:0090304"... | [
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016070",
"GO:0016071",
"GO:0032774",
"GO:0034654",
"GO:0043170",
"GO:0044238",
"GO:0090304"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q70Z53-F1-model_v6.pdb | {"IPR050645": [52, 265], "IPR019129": [104, 219]} | - IPR050645: Histidine Acid Phosphatase (family) [52-265]
- IPR019129: Folate-sensitive fragile site protein Fra10Ac1 (family) [104-219] | - Zinc finger protein 32
- Spliceosome-associated protein CWC27 homolog
- Splicing factor ESS-2 homolog
- Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
- Calcium homeostasis endoplasmic reticulum protein
- Leucine-rich glioma-inactivated protein 1
- Splicing factor 3B subunit 2
- Protein Red | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
P70266 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | Synthesis and degradation of fructose 2,6-bisphosphate | Mus musculus (Mouse) | 471 | MSREMGELTQTRLQKIWIPHSSSSSLLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYRNYEFFRPDNMEAQLIRKQCALAALKDVHKYLSREEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPDIIAENIKQVKLGSPDYIDCDQEKVLEDFLKRIECYEINYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHVQSRTAYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQSISSLKVWTSHMKRTIQTAEALGVPY... | [
"GO:0006109",
"GO:0006110",
"GO:0006140",
"GO:0008150",
"GO:0009892",
"GO:0009894",
"GO:0009895",
"GO:0010563",
"GO:0019219",
"GO:0019222",
"GO:0030811",
"GO:0030812",
"GO:0033121",
"GO:0033122",
"GO:0043467",
"GO:0043470",
"GO:0045820",
"GO:0045912",
"GO:0045934",
"GO:0045936"... | [
"GO:0006109",
"GO:0006110",
"GO:0006140",
"GO:0008150",
"GO:0009892",
"GO:0009894",
"GO:0009895",
"GO:0010563",
"GO:0019219",
"GO:0019222",
"GO:0030811",
"GO:0030812",
"GO:0033121",
"GO:0033122",
"GO:0043467",
"GO:0043470",
"GO:0045820",
"GO:0045912",
"GO:0045934",
"GO:0045936"... | [
"GO:0003674",
"GO:0003824",
"GO:0004331",
"GO:0016787",
"GO:0016788",
"GO:0016791",
"GO:0019203",
"GO:0042578",
"GO:0050308"
] | [] | AF-P70266-F1-model_v6.pdb | {"IPR027417": [41, 252], "IPR029033": [250, 470], "IPR003094": [32, 453], "IPR013078": [253, 439], "IPR013079": [31, 251], "IPR001345": [256, 265]} | - IPR013078: Histidine phosphatase superfamily, clade-1 (family) [253-439]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [41-252]
- IPR029033: Histidine phosphatase superfamily (homologous_superfamily) [250-470]
- IPR001345: Phosphoglycerate/bisphosphoglycerate mutase, active... | - Fructose-1,6-bisphosphatase isozyme 2
- Fructose-1,6-bisphosphatase 1
- Fructose-2,6-bisphosphatase TIGAR
- ATP-dependent 6-phosphofructokinase, liver type
- ATP-dependent 6-phosphofructokinase, muscle type
- ATP-dependent 6-phosphofructokinase, platelet type
- cAMP-dependent protein kinase catalytic subunit beta
- c... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0019203 (carbohydrate phosphatase activity), GO:0050... | |
P0C2W1 | F-box/SPRY domain-containing protein 1 | Component of E3 ubiquitin ligase complex consisting of FBXO45, MYCBP2 and SKP1. Functions in substrate recognition but also plays an important role in assembly of the complex. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Regulates neuron migration during bra... | Homo sapiens (Human) | 286 | Secreted. Postsynaptic cell membrane. Presynaptic cell membrane. Nucleus. Note=Secreted by a non-classical mechanism | MAAPAPGAGAASGGAGCSGGGAGAGAGSGSGAAGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005829",
"GO:0005886",
"GO:0016020",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005829",
"GO:0005886",
"GO:0016020",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0071944",
"GO:0110165"
] | AF-P0C2W1-F1-model_v6.pdb | {"IPR036047": [38, 87], "IPR013320": [79, 283], "IPR043136": [110, 284], "IPR050672": [44, 278], "IPR001810": [33, 84], "IPR001870": [92, 284], "IPR035784": [112, 286], "IPR003877": [152, 284]} | - IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [79-283]
- IPR001870: B30.2/SPRY domain (domain) [92-284]
- IPR003877: SPRY domain (domain) [152-284]
- IPR001810: F-box domain (domain) [33-84]
- IPR043136: B30.2/SPRY domain superfamily (homologous_superfamily) [110-284]
- I... | - E3 ubiquitin-protein ligase MYCBP2
- S-phase kinase-associated protein 1
- S-phase kinase-associated protein 1
- Cullin-1
- Protein unc-13 homolog A
- SPRY domain-containing protein 3
- E3 ubiquitin-protein ligase SIAH1
- F-box/WD repeat-containing protein 7
- WD repeat-containing protein 53
- MAGUK p55 subfamily mem... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological p... |
P78594 | Cytosine deaminase | Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 150 | Cytoplasm. Nucleus | MTFDDKKGLQVALDQAKKSYSEGGIPIGSCIISSDDTVLGQGHNERIQKHSAILHGEMSALENAGRLPGKTYKDCTIYTTLSPCSMCTGAILLYGFKRVVMGENVNFLGNEKLLIENGVEVVNLNDQECIDLMAKFIKEKPQDWNEDIGE | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-P78594-F1-model_v6.pdb | {"IPR016193": [5, 148], "IPR002125": [3, 121], "IPR016192": [55, 91]} | - IPR002125: Cytidine and deoxycytidylate deaminase domain (domain) [3-121]
- IPR016193: Cytidine deaminase-like (homologous_superfamily) [5-148]
- IPR016192: APOBEC/CMP deaminase, zinc-binding (binding_site) [55-91] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016814 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines), GO:00192... | |
Q5A7S7 | Fork-head transcriptional regulator 2 | Transcription factor required for the morphogenesis of true hyphal as well as yeast cells. Contributes to virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 687 | Nucleus | MSAQFITPKKRPHSPLDSNELLPSFEDPQDMINAVVSTLSAPEEKTNVSIAYANEKNQATEIQAYAKIAGKDWTFYVKSLAVSIGRNIELSAPSNTNITTPLIDIDLGPAKVVSRSHAAITYNLDLRCWELKVLGRNGARIDGQKVNVDSPNVNALHSGAILDIGGTQMMFILPDAPAVVAPKMLEKCLLRYKEQQQQQNKRISSGPGIGGSTSFQMFDKAHLTHSPSSISANSLQSNLDQDLSKEEAKDIKPPYSYATMITQAILSNPQGVMSLSEIYNWIADHYAYYKYSKTGWQNSIRHNLSLNKAFEKVPRRPNEP... | [
"GO:0000902",
"GO:0001558",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0006974",
"GO:0008150",
"GO:0009653",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030308",
"GO:0030447",
"GO:0032502",
"GO:0033554",
"GO:0040007"... | [
"GO:0000902",
"GO:0001558",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0006974",
"GO:0008150",
"GO:0009653",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030308",
"GO:0030447",
"GO:0032502",
"GO:0033554",
"GO:0040007"... | [
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5A7S7-F1-model_v6.pdb | {"IPR008984": [68, 176], "IPR036388": [238, 343], "IPR036390": [251, 340], "IPR000253": [81, 165], "IPR001766": [250, 350], "IPR018122": [252, 265], "IPR030456": [296, 302]} | - IPR000253: Forkhead-associated (FHA) domain (domain) [81-165]
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [68-176]
- IPR018122: Fork head domain conserved site1 (conserved_site) [252-265]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [238-343]
- IPR036390... | - Transcription factor of morphogenesis MCM1
- Cyclin-dependent kinase 1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (... |
Q59ZC8 | Fork-head transcriptional regulator FHL1 | In complex with IFH1, acts as a transcriptional regulator of rRNA and ribosomal protein genes. The FHL1-IFH1 complex is targeted to the ribosomal protein genes by the DNA-binding factor TBF1 | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,152 | Nucleus | MSHIDGDDHMTKDLIDSLESKDNDLSLVTSNTQIPDVEVANLTHDADEINQLFDTATNNVLPESNKKDKPIDTQDLHEDDPKAVPKTTSNGESTSNSNSVSPKLLPNDGKSTPKIQKELRRKSTFVPVTSNSKSLEPSEDDNNNNNNNSRISAYARLDFENFTFFVQTLQVVLGRKSNDETLQQNVDVHLSSKKAISRRHAKIFYNFGTQRFEISILGRNGAFVDNVFVEKGLTIPLTDGNKIQIGDIPFKFVLPSNEPNEENNNQDSSEKQFNPSDAINLRSNLYSKSSSPQSSPKRKPQPSKKVKKEPVSASNTSKDI... | [
"GO:0006139",
"GO:0006351",
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009303",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010467",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0016070",
"GO:0016072"... | [
"GO:0006139",
"GO:0006351",
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009303",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010467",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0016070",
"GO:0016072"... | [
"GO:0000976",
"GO:0001067",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003690",
"GO:0005488",
"GO:0043565",
"GO:1990837"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59ZC8-F1-model_v6.pdb | {"IPR008984": [150, 263], "IPR036388": [658, 751], "IPR036390": [658, 748], "IPR053364": [13, 1049], "IPR000253": [170, 246], "IPR001766": [657, 740]} | - IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [150-263]
- IPR000253: Forkhead-associated (FHA) domain (domain) [170-246]
- IPR053364: Fork-head Transcriptional Regulator (family) [13-1049]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [658-751]
- IPR036390: W... | - Transcriptional regulator IFH1
- Transcription factor TBF1
- Proteasome subunit beta | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (... |
Q8BSM5 | GRB2-associated-binding protein 3 | Mus musculus (Mouse) | 595 | MSTGDTVCMGWLIKSPPERKLQRYAWRKRWFVLRRGRMSGNPDVLEYYRNKHSNKPIRVIDLSECTVWKHAGPGFIRKEFQKNFVFIVKTTSRTFYLVAKTEEEMQVWVHSISQVCNFSHLEDGADSMESLSHMPSSFQPSPASSLHTVHVANSALLKDDRNTNSVVTEETRRESEFLFLPDYLILSNCETGRLHHASLPTRCDSWSNSNHSLAQTSFDDVFLDGLQPFISNNLVHPLHHGKVSQDFPSIRPQASLIWNREINGPSRNLMSSSPLLESSLNPTVHVEEKQVSLPSGVKELNIMSNTPPPRPPKPSYLSEQ... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-Q8BSM5-F1-model_v6.pdb | {"IPR011993": [1, 128], "IPR046355": [1, 594], "IPR001849": [5, 119]} | - IPR001849: Pleckstrin homology domain (domain) [5-119]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1-128]
- IPR046355: GRB2-associated-binding protein 1-4-like (family) [1-594] | - Growth factor receptor-bound protein 2
- Tyrosine-protein phosphatase non-receptor type 11 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure developm... | ||
A6M9B7 | O-antigen biosynthesis glycosyltransferase WclY | Involved in the assembly of the O-repeating unit during O- antigen biosynthesis. Glucosyltransferase accountable for the alpha-D- Glc-1,4-beta-D-Gal linkage within the O-antigen. Transfers alpha-1,4-Glc to the Gal moiety of a specific Gal-beta1-3GalNAc-alpha-OPO3-PO3-phenoxyundecyl (Gal-beta1- 3GalNAc-PP-PhU) synthetic... | Escherichia coli | 353 | Membrane; Single-pass membrane protein | MKIAYVVSSKKKCGPNIVILNIVKELANKHEMEIFFLDESDDDVFECVNVKSTQIKKASDLKEHLKRFDIIHSSGIRPDALVVLCKVIYRVKCKIITTIHNYVFQDLYYSYGLVKSLIGGLLWCSIWLFFDKLVILSKNADNYYWFLPSAKKNIIYNGIDDNDCLQNKKCNYRKEFNIPDDGILAGSCANLTKRKGIDLVIQTLTKEHKIYYIVAGNGIEKHNLINLVKARKLHERVYFIDFLDEPESFMSQLDVFLMPSRSEGFGLTVLESTKLGIPVITSNIPIFMELFDQMCLTFDIKNPSTLIDVITYAKKNRLHL... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016757",
"GO:0016758",
"GO:0046527"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009274",
"GO:0009276",
"GO:0030312",
"GO:0030313",
"GO:0071944",
"GO:0110165"
] | AF-A6M9B7-F1-model_v6.pdb | {"IPR028098": [14, 161], "IPR001296": [171, 319]} | - IPR028098: Glycosyltransferase subfamily 4-like, N-terminal domain (domain) [14-161]
- IPR001296: Glycosyl transferase, family 1 (domain) [171-319] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0000030 (mannosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:000815... | |
P0AEQ3 | Glutamine-binding periplasmic protein | Involved in a glutamine-transport system GlnHPQ | Escherichia coli (strain K12) | 248 | Periplasm | MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGDKYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPNIDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYKKWFGTEPK | [
"GO:0006810",
"GO:0006865",
"GO:0006868",
"GO:0008150",
"GO:0015711",
"GO:0015804",
"GO:0015849",
"GO:0046942",
"GO:0051179",
"GO:0051234",
"GO:0071705",
"GO:0003674",
"GO:0005488",
"GO:0031406",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0043177",
"GO:0070406"
] | [
"GO:0006810",
"GO:0006865",
"GO:0006868",
"GO:0008150",
"GO:0015711",
"GO:0015804",
"GO:0015849",
"GO:0046942",
"GO:0051179",
"GO:0051234",
"GO:0071705"
] | [
"GO:0003674",
"GO:0005488",
"GO:0031406",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0043177",
"GO:0070406"
] | [] | AF-P0AEQ3-F1-model_v6.pdb | {"IPR001320": [26, 245], "IPR001638": [26, 246], "IPR044132": [26, 244], "IPR018313": [48, 61]} | - IPR044132: Glutamine-binding periplasmic protein GlnH, type 2 periplasmic binding protein fold (domain) [26-244]
- IPR001638: Solute-binding protein family 3/N-terminal domain of MltF (domain) [26-246]
- IPR018313: Solute-binding protein family 3, conserved site (conserved_site) [48-61]
- IPR001320: Ionotropic glutam... | - Glutamine transport ATP-binding protein GlnQ
- Glutamine transport system permease protein GlnP
- Glutamine transport system permease protein GlnP
- Glutamine transport system permease protein GlnP
- Glutamine transport system permease protein GlnP
- Glutamate/aspartate import permease protein GltK
- Glutamate/aspart... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0036094 (small molecule binding), GO:0022857 (transmembrane transporter activity), GO:0043167 (ion binding), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0005342 (organic acid tra... |
P0ACL0 | Glycerol-3-phosphate regulon repressor | Repressor of the glycerol-3-phosphate regulon | Escherichia coli (strain K12) | 252 | MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELAEQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFISQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0010468",
"GO:0010556",
"GO:0010558",
"GO:0010605",
"GO:0019219",
"GO:0019222",
"GO:0045892",
"GO:0045934",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0051253",
"GO:0060255"... | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0010468",
"GO:0010556",
"GO:0010558",
"GO:0010605",
"GO:0019219",
"GO:0019222",
"GO:0045892",
"GO:0045934",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0051253",
"GO:0060255"... | [] | [] | AF-P0ACL0-F1-model_v6.pdb | {"IPR036388": [1, 57], "IPR036390": [3, 76], "IPR037171": [73, 233], "IPR050313": [1, 250], "IPR001034": [3, 61], "IPR014036": [74, 231], "IPR018356": [6, 40]} | - IPR037171: NagB/RpiA transferase-like (homologous_superfamily) [73-233]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [1-57]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [3-76]
- IPR018356: Transcription regulator, HTH DeoR-type, conserved ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (re... | ||
Q61606 | Glucagon receptor | G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes... | Mus musculus (Mouse) | 485 | Cell membrane; Multi-pass membrane protein. Note=Is rapidly internalized after ligand-binding | MPLTQLHCPHLLLLLLVLSCLPEAPSAQVMDFLFEKWKLYSDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPPNTTANISCPWYLPWYHKVQHRLVFKRCGPDGQWVRGPRGQPWRNASQCQLDDEEIEVQKGVAKMYSSQQVMYTVGYSLSLGALLLALVILLGLRKLHCTRNYIHGNLFASFVLKAGSVLVIDWLLKTRYSQKIGDDLSVSVWLSDGAMAGCRVATVIMQYGIIANYCWLLVEGVYLYSLLSLATFSERSFFSLYLGIGWGAPLLFVIPWVVVKCLFENVQCWTSNDNMGFWWILRIPVFLALLINF... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q61606-F1-model_v6.pdb | {"IPR036445": [15, 150], "IPR003290": [12, 384], "IPR050332": [13, 434], "IPR003291": [18, 484], "IPR000832": [141, 404], "IPR001879": [43, 131], "IPR017981": [142, 405], "IPR017983": [59, 408]} | - IPR036445: GPCR family 2, extracellular hormone receptor domain superfamily (homologous_superfamily) [15-150]
- IPR003290: GPCR, family 2, glucagon-like peptide-1/glucagon receptor (family) [12-384]
- IPR003291: GPCR, family 2, glucagon receptor (family) [18-484]
- IPR050332: G-protein coupled receptor 2 (family) [13... | - Pro-glucagon
- Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
- Guanine nucleotide-binding protein G(q) subunit alpha
- Gastric inhibitory polypeptide
- Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
- Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
- Guanine n... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-... |
E3Q1H1 | Glucosamine 6-phosphate N-acetyltransferase | Involved in the biosynthesis of UDP-N-acetyl-alpha-D- glucosamine. Catalyzes the formation of N-acetyl-D-glucosamine 6- phosphate from acetyl-coenzyme A (acetyl-CoA) and D-glucosamine 6- phosphate | Trypanosoma brucei brucei | 147 | Glycosome. Note=Predominantly located in glycosome microbodies in the bloodstream form of T.brucei | MTDIVDLELRVLEESDLSSHLELLGHLTEAPPLSGVELANIADMRRRAGIVTKVFCHQPTGRIVGSASLMIQPKFTRGGRAVGHIEDVVVDPSYRGAGLGKALIMDLCEISRSKGCYKVILDSSEKSLPFYEKLGFRAHERQMRLDL | [
"GO:0006022",
"GO:0006023",
"GO:0006040",
"GO:0006047",
"GO:0006048",
"GO:0006139",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009225",
"GO:0009226",
"GO:0009987",
"GO:0019637",
"GO:0030309",
"GO:0030311",
"GO:0034654"... | [
"GO:0006022",
"GO:0006023",
"GO:0006040",
"GO:0006047",
"GO:0006048",
"GO:0006139",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009225",
"GO:0009226",
"GO:0009987",
"GO:0019637",
"GO:0030309",
"GO:0030311",
"GO:0034654"... | [
"GO:0003674",
"GO:0003824",
"GO:0004343",
"GO:0005488",
"GO:0005515",
"GO:0008080",
"GO:0016407",
"GO:0016410",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005777",
"GO:0020015",
"GO:0042579",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-E3Q1H1-F1-model_v6.pdb | {"IPR016181": [6, 144], "IPR039143": [5, 143], "IPR000182": [7, 147]} | - IPR000182: GNAT domain (domain) [7-147]
- IPR039143: Glucosamine 6-phosphate N-acetyltransferase-like (family) [5-143]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [6-144] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransfe... | |
B8QSK0 | O-antigen biosynthesis glycosyltransferase WclY | Involved in the assembly of the O-repeating unit during O- antigen biosynthesis. N- acetylglucosamine transferase accountable for the alpha-D-GlcNAc-1,4- beta-D-Gal linkage within the O-antigen | Escherichia coli | 353 | Membrane; Single-pass membrane protein | MKIAYVVSSKKKCGPNIVILNIVKELANKHEMEIFFLDESDDDVFECVNVKSTQIKKASDLKEHLKRFDIIHSSGIRPDALVVLCKVIYRVKCKIITTIHNYVFQDLYYSYGLVKSLIWGLLWCSIWLFFDKLVILSKNADNYYWFLPSAKKNIIYNGIDDNDCLQNKKCNYRKEFNIPDDGILAGSCANLTKCKGIDLVIQTLTKEHKIYYIVAGDGIEKHNLINLVKARKLHERVYFIDFLDEPESFMSQLDVFLMPSRSEGFGLTVLESTKLGIPVITSNIPIFMELFDQMCLTFDIKNPSTLIDVITYAKKNRLHL... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0000271",
"GO:0005975",
"GO:0005976",
"GO:0006629",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008653",
"GO:0009058",
"GO:0009059",
"GO:0009103",
"GO:0009243",
"GO:0009987",
"GO:0016043",
"GO:0016051",
"GO:0022607",
"GO:0043163",
"GO:0043165",
"GO:0043170",
"GO:0044085"... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016757"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009274",
"GO:0009276",
"GO:0030312",
"GO:0030313",
"GO:0071944",
"GO:0110165"
] | AF-B8QSK0-F1-model_v6.pdb | {"IPR028098": [14, 161], "IPR001296": [171, 319]} | - IPR028098: Glycosyltransferase subfamily 4-like, N-terminal domain (domain) [14-161]
- IPR001296: Glycosyl transferase, family 1 (domain) [171-319] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0000030 (mannosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:000815... | |
Q8SZ63 | Golgin-84 | May be involved in maintaining Golgi structure and in intra- Golgi transport | Drosophila melanogaster (Fruit fly) | 516 | Golgi apparatus membrane; Single- pass type IV membrane protein | MSSWITGLADKAENILNKLDQNAATALQTENATGSADPMRRSMTSSTQSLSTSLKSTLSPVRRSGANSSSSVKSDGGVSVVTKDMRQKMTTSASFSNSPDISANSMDTNELAAFKIALNEITAERDELRLRLEDLNNETEKFDLHQHTQVLEALVKSLSEERDKAVHDYNEAQAANMAYVHSISELETNLAKLQQEYISAAHKLQMQTKETEQQRQELQEYRIKAQRALQAKDSLIAELKAKPTEEGADPNLVSKDSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQERQRQVELSSARQREETLAKELRQARE... | [
"GO:0006810",
"GO:0006891",
"GO:0006903",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0016192",
"GO:0048193",
"GO:0051179",
"GO:0051234",
"GO:0051640",
"GO:0051641",
"GO:0051648",
"GO:0051649",
"GO:0051650",
"GO:0051656",
"GO:0071840",
"GO:0099022",
"GO:0099041",
"GO:0003674"... | [
"GO:0006810",
"GO:0006891",
"GO:0006903",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0016192",
"GO:0048193",
"GO:0051179",
"GO:0051234",
"GO:0051640",
"GO:0051641",
"GO:0051648",
"GO:0051649",
"GO:0051650",
"GO:0051656",
"GO:0071840",
"GO:0099022",
"GO:0099041"
] | [
"GO:0003674",
"GO:0038024"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005794",
"GO:0005801",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0033106",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098588",
"GO:0110165"
] | AF-Q8SZ63-F1-model_v6.pdb | {"IPR019177": [211, 515]} | - IPR019177: Golgin subfamily A member 5 (family) [211-515] | - Golgi microtubule-associated protein, isoform D
- Grasp65
- Conserved oligomeric Golgi complex subunit 7
- GH05665p
- Golgi matrix protein 130 kD
- Conserved oligomeric Golgi complex subunit 8 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0051020 (GTPase binding), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO... |
Q54WG6 | Histone H2AX | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl... | Dictyostelium discoideum (Social amoeba) | 154 | Nucleus. Chromosome | MSETKPASSKPAAAAKPKKVIPRVSRTGEPKSKPESRSARAGITFPVSRVDRLLREGRFAPRVESTAPVYLAAVLEYLVFEILELAHNTCSISKKTRITPQHINWAVGNDLELNSLFQHVTIAYGGVLPTPQQSTGEKKKKPSKKAAEGSSQIY | [
"GO:0003674",
"GO:0005198",
"GO:0030527",
"GO:0000785",
"GO:0000786",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0032991",
"GO:0032993",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0005198",
"GO:0030527"
] | [
"GO:0000785",
"GO:0000786",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0032991",
"GO:0032993",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q54WG6-F1-model_v6.pdb | {"IPR009072": [22, 148], "IPR002119": [22, 142], "IPR007125": [31, 107], "IPR032454": [112, 145]} | - IPR009072: Histone-fold (homologous_superfamily) [22-148]
- IPR002119: Histone H2A (family) [22-142]
- IPR007125: Core Histone H2A/H2B/H3 domain (domain) [31-107]
- IPR032454: Histone H2A, C-terminal domain (domain) [112-145] | - Histone H2B.v3
- Histone H4
- Histone H2A.z
- PWWP domain-containing protein
- Histone H3.3 type c
- Histone H3.3 type a
- ATP-dependent DNA helicase ku70
- Histone H3.3 type b
- Suppressor of Mek1
- Histone H1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006325 (chro... |
A0A7P0TBJ1 | HUWE1-associated protein modifying stress responses 2 | Together with HAPSTR1 plays a central regulatory role in the cellular response to molecular stressors, such as DNA damage, nutrient scarcity, and protein misfolding. Regulates these multiple stress response signaling pathways by stabilizing HAPSTR1, but also independently of HAPSTR1 | Homo sapiens (Human) | 273 | Nucleus | MEEQQKEGEAEVAEHWFSKWERQCLAEAEQEEQLPPELQEEAAAELAGLKSEKQKLWHLFQISATAVAQLYKDSGCQQQGLSMWDPFQNAAMAVTSLYKESGDAHQRSFDLGVQVGHQRRIKDVLEWVKKGRSTIRREDLISFLCGKVPPAPPPPRTPRTPPKPPTGVTSQAVATESSSSVDVDLQPFQEAIALHGLSGAMAGISMRSGDSPQDSGVASSGRRKTSFLEDDLNPFDSEELALHLDSGGIRKRTSAQCSDGITDSPIQKRNRMV | [
"GO:0008150",
"GO:0031647",
"GO:0050821",
"GO:0065007",
"GO:0065008",
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0019899",
"GO:0031625",
"GO:0044389",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [
"GO:0008150",
"GO:0031647",
"GO:0050821",
"GO:0065007",
"GO:0065008"
] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0019899",
"GO:0031625",
"GO:0044389"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-A0A7P0TBJ1-F1-model_v6.pdb | {"IPR040308": [1, 273], "IPR029196": [21, 271]} | - IPR029196: HUWE1-associated protein modifying stress responses-like (family) [21-271]
- IPR040308: HUWE1-associated protein modifying stress responses (family) [1-273] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (re... | |
P0AES9 | Acid stress chaperone HdeA | Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non- specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral p... | Escherichia coli (strain K12) | 110 | Periplasm | MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLAVDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGEWDKIKKDM | [
"GO:0005575",
"GO:0030288",
"GO:0030313",
"GO:0042597",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0030288",
"GO:0030313",
"GO:0042597",
"GO:0110165"
] | AF-P0AES9-F1-model_v6.pdb | {"IPR038303": [22, 110], "IPR036831": [30, 108], "IPR024972": [1, 107], "IPR010486": [11, 96]} | - IPR010486: HNS-dependent expression A/B (family) [11-96]
- IPR024972: HNS-dependent expression A (family) [1-107]
- IPR036831: HNS-dependent expression A superfamily (homologous_superfamily) [30-108]
- IPR038303: HNS-dependent expression A/B superfamily (homologous_superfamily) [22-110] | - Glutamate decarboxylase beta
- Glutamate decarboxylase beta
- Glutamate decarboxylase beta
- Acid stress chaperone HdeB
- Protein HdeD
- Glutamate/gamma-aminobutyrate antiporter
- Glutamate/gamma-aminobutyrate antiporter
- Glutamate decarboxylase alpha
- Transcriptional regulator GadE
- Outer membrane protein Slp | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044183 (protein folding chaperone), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0051087 (chaperone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:000... |
A0A1D8PCL1 | High-affinity glucose transporter 1 | High-affinity glucose transporter. Acts as a multifunctional complement-evasion molecule that causes down-regulation of complement activation by acquisition of human complement factors FH and C4BP. Also functions as a human immunodeficiency virus (HIV) receptor via binding the viral gp160 protein. Modulates hyphae form... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 545 | Cell membrane; Multi-pass membrane protein | MSSKIERIFSGPALKINTYLDKLPKIYNVFFIASISTIAGMMFGFDISSMSAFIGAEHYMRYFNSPGSDIQGFITSSMALGSFFGSIASSFVSEPFGRRLSLLTCAFFWMVGAAIQSSVQNRAQLIIGRIISGIGVGFGSAVAPVYGAELAPRKIRGLIGGMFQFFVTLGIMIMFYLSFGLGHINGVASFRIAWGLQIVPGLCLFLGCFFIPESPRWLAKQGQWEAAEEIVAKIQAHGDRENPDVLIEISEIKDQLLLEESSKQIGYATLFTKKYIQRTFTAIFAQIWQQLTGMNVMMYYIVYIFQMAGYSGNSNLVASS... | [
"GO:0002682",
"GO:0002683",
"GO:0002697",
"GO:0002698",
"GO:0002920",
"GO:0002921",
"GO:0006810",
"GO:0006950",
"GO:0008150",
"GO:0008643",
"GO:0008645",
"GO:0009266",
"GO:0009268",
"GO:0009408",
"GO:0009605",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0015749",
"GO:0030447"... | [
"GO:0002682",
"GO:0002683",
"GO:0002697",
"GO:0002698",
"GO:0002920",
"GO:0002921",
"GO:0006810",
"GO:0006950",
"GO:0008150",
"GO:0008643",
"GO:0008645",
"GO:0009266",
"GO:0009268",
"GO:0009408",
"GO:0009605",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0015749",
"GO:0030447"... | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005886",
"GO:0016020",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-A0A1D8PCL1-F1-model_v6.pdb | {"IPR036259": [25, 498], "IPR003663": [25, 490], "IPR050360": [27, 523], "IPR005828": [34, 494], "IPR020846": [32, 483], "IPR005829": [89, 350]} | - IPR036259: MFS transporter superfamily (homologous_superfamily) [25-498]
- IPR050360: Major Facilitator Superfamily Sugar Transporters (family) [27-523]
- IPR005828: Major facilitator, sugar transporter-like (family) [34-494]
- IPR020846: Major facilitator superfamily domain (domain) [32-483]
- IPR005829: Sugar trans... | - Hgt2p
- Bifunctional protein GAL10 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0051119 (sugar transmembrane transporter activity), GO:0015145 (monosaccharide transmembrane transporter activity... |
Q5AQ33 | Heat shock transcription factor | DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription. With HSP90, is required for the modulation of the chaperone levels in response to growth temperature, rather than the activation of acute responses to sudden thermal transitions. Activated during inf... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 760 | Nucleus | MIMNMTTDYRDPLLDLFGTESNSGNETSSPSDIPVINRSGTFNQQQFSPLLTQQSLYNTPNSGSTPNIFDPNYTQMQEEQTSPSSNKLQPEDPPRKKRNTRSQTKIHQQSEGDEYNSNDYKDSIDLDKPPVVEPSPPFFVESDTTPEFVIPTPTSEQQQQQHHELIAQDYQRSNNSNQFGNLTHYEPNLPPLPPLSESILPQTNTFHPLVLPHDPRHAITAGPANNSQQQQQQQQQDSSIPSDGISSKIQQLHAPSLSNNQSASQRKKKESSGPKTRPAFVMKIWSMVNDPANHEYIRWNDDGKTFQVFHREDFMKVILP... | [
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009266",
"GO:0009408",
"GO:0009628",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0019219",
"GO:0019222",
"GO:0033554",
"GO:0034605",
"GO:0045893"... | [
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009266",
"GO:0009408",
"GO:0009628",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0019219",
"GO:0019222",
"GO:0033554",
"GO:0034605",
"GO:0045893"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5AQ33-F1-model_v6.pdb | {"IPR036388": [273, 386], "IPR036390": [277, 384], "IPR000232": [276, 385]} | - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [277-384]
- IPR000232: Heat shock factor (HSF)-type, DNA-binding (domain) [276-385]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [273-386] | - Hsp90 cochaperone
- Heat shock protein 90 homolog
- Heat shock protein HSP70
- Chaperone ATPase
- Heat shock protein SSA2
- Flavin reductase like domain-containing protein
- Uncharacterized protein
- Mitogen-activated protein kinase HOG1
- Type II HSP40 co-chaperone
- Ssz1p | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biologica... |
Q5AG71 | Serine/threonine-protein kinase HSL1 | Protein kinase involved in determination of morphology during the cell cycle of both yeast-form and hyphal cells via regulation of SWE1 and CDC28. Regulates pseudohypha formation, but is not required for septin ring organization or septum formation. Plays an essential role in virulence in a mouse model | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,462 | Bud neck. Note=In the hyphal cells, localizes at a potent septation site before the completion of septum formation | MSTVVNRRSSHQFDSPSNHLDHSSSMNVDKVVQSVTNATKRLSQISTNTNNSNKKRKTQNKIGPWKLGRTLGRGSTGRVRLAKNTTTGQLAAVKIVPKSNFKKLENPKYKRSKEDATRLPYGIEREIIIMKLISHPNIMGLYDVWENKNDLYLILEYIEGGELFDYLIKRGKLQEYEAINYFKQIINGINYLHQFNICHRDLKPENLLLDFNKNIKIADFGMAALEVKEKLLETSCGSPHYASPEIVAGKNYHGAPSDIWSCGIILFALLTGHLPFDDENIRKLLLKVQSGKFNMPPELSFEAKDLITKMLKVNPRERIT... | [
"GO:0001403",
"GO:0001558",
"GO:0006950",
"GO:0007124",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010570",
"GO:0016049",
"GO:0030308",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0040008",
"GO:0042149",
"GO:0042594",
"GO:0044182"... | [
"GO:0001403",
"GO:0001558",
"GO:0006950",
"GO:0007124",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010570",
"GO:0016049",
"GO:0030308",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0040008",
"GO:0042149",
"GO:0042594",
"GO:0044182"... | [
"GO:0003674",
"GO:0003824",
"GO:0004672",
"GO:0016301",
"GO:0016740",
"GO:0016772",
"GO:0016773",
"GO:0140096"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005856",
"GO:0005933",
"GO:0005935",
"GO:0005938",
"GO:0005940",
"GO:0030427",
"GO:0032156",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0071944",
"GO:0110165"
] | AF-Q5AG71-F1-model_v6.pdb | {"IPR011009": [62, 331], "IPR000719": [65, 330], "IPR031850": [1326, 1455], "IPR008271": [197, 209], "IPR017441": [71, 94]} | - IPR008271: Serine/threonine-protein kinase, active site (active_site) [197-209]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [62-331]
- IPR017441: Protein kinase, ATP binding site (binding_site) [71-94]
- IPR000719: Protein kinase domain (domain) [65-330]
- IPR031850: Fungal kinase ass... | - Mitosis inhibitor protein kinase SWE1
- Mitogen-activated protein kinase HOG1
- Cdh1p
- M-phase inducer phosphatase
- Anaphase promoting complex subunit
- Serine/threonine-protein kinase GIN4
- Anaphase promoting complex subunit
- Septin | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring pho... |
Q59PF9 | Hyphal wall protein 2 | GPI-anchored cell wall protein required for mating efficiency, biofilm formation, adhesion, filamentous growth, and oxidative stress tolerance. Involved in normal disseminated infection in a mouse systemic candidiasis model | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 908 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=localizes to the cell wall of hyphae | MRFATTQLATLACFILTAEATFPLRGLFNDAPVDVDLGVYHEESGNNKEQKVDGFNMSPNIKKRTNENNAANVVSTNGGLFITSTKELKTTVVVTSCFNNVCSETSITTPKTAVTATTSKHSTSKPTYTTTSKHSTSHSSTPASTSKHSTSTSTHPATSEHSTSKSTHATSSKHSTSKSSVSVTTSKHSTHDTTSKSFVTPPASSTTSEHTKHKSHKPSKTVVTLTSCSNNACSQSEITTGAIVVTDKETVYTTYCPLTDTETETESTTATTSKHSTHTTTSKHSSVESTSVTSSSKHSVSKSTDVTTSKHSSSESSHAT... | [
"GO:0008150",
"GO:0009987",
"GO:0030447",
"GO:0040007",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0044403",
"GO:0044406",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743",
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312"... | [
"GO:0008150",
"GO:0009987",
"GO:0030447",
"GO:0040007",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0044403",
"GO:0044406",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0030446",
"GO:0071944",
"GO:0110165"
] | AF-Q59PF9-F1-model_v6.pdb | {"IPR025928": [221, 748]} | - IPR025928: Flocculin type 3 repeat (repeat) [221-748] | - Agglutinin-like protein 3
- Hyphally regulated cell wall protein 1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0044010 (sin... |
Q59RW5 | N-acetylglucosamine kinase 1 | Component of the N-acetylglucosamine catabolic cascade that phosphorylates N-acetylglucosamine (GlcNAc), and allows the unique ability to utilise GlcNAc as carbon source. Converts GlcNAc to GlcNAc- 6-P. Also able to phosphorylate glucose, glucosamine (GlcN), and mannose. Galactose, fructose, N-acetylmannosamine (ManNAc... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 493 | Cytoplasm. Nucleus. Mitochondrion. Note=Localized in cytoplasm and nucleus in a filamentation-inducing medium whereas in 2% GlcNAc, where catabolism is more prominent, a major fraction is seen to be present in cytoplasm. Localizes to mitochondria in non-fermentative carbon sources like ethanol | MTETSISGLRGPKSMYFMEIVDVSSQESSVLSSIVESFTSAVSASNLGVYSDEVLCDIKSSLKENSPITMLPNYNVSPTGDEHGQYLVIDLGGSTLRIAVVDISKPHPNLSRSERITIVVEKSWIIGNDFKRIDGEFFKYIGSKINEILMGQNVIDVKSVINTGITWSFPLETTDYNRGKIKHVSKGYTVGEDIYDKDLKMVLEDTLRQEYGLTLDVQSILNDSLAVYSAGCFIDSKMKLAMVLGTGINMCCSLKRSSDIHPSKMLADATLFNCELSLFGQNLCKDFATKYDIIIDKRFAGLSHHFKTFMEPDPITKTLF... | [
"GO:0006022",
"GO:0006023",
"GO:0006030",
"GO:0006031",
"GO:0006040",
"GO:0006041",
"GO:0006043",
"GO:0006044",
"GO:0006046",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009058",
"GO:0009059",
"GO:0009272",
"GO:0009987",
"GO:0030447",
"GO:0040007",
"GO:0042546",
"GO:0043170"... | [
"GO:0006022",
"GO:0006023",
"GO:0006030",
"GO:0006031",
"GO:0006040",
"GO:0006041",
"GO:0006043",
"GO:0006044",
"GO:0006046",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009058",
"GO:0009059",
"GO:0009272",
"GO:0009987",
"GO:0030447",
"GO:0040007",
"GO:0042546",
"GO:0043170"... | [
"GO:0003674",
"GO:0003824",
"GO:0004396",
"GO:0016301",
"GO:0016740",
"GO:0016772",
"GO:0016773",
"GO:0019158",
"GO:0019200",
"GO:0045127"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0005739",
"GO:0005829",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q59RW5-F1-model_v6.pdb | {"IPR043129": [30, 491], "IPR001312": [27, 491], "IPR022672": [41, 230], "IPR022673": [240, 490]} | - IPR022673: Hexokinase, C-terminal (domain) [240-490]
- IPR022672: Hexokinase, N-terminal (domain) [41-230]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [30-491]
- IPR001312: Hexokinase (family) [27-491] | - Glucosamine-6-phosphate isomerase
- N-acetylglucosamine-6-phosphate deacetylase
- ATP-dependent 6-phosphofructokinase
- ATP-dependent 6-phosphofructokinase
- Glucose-6-phosphate isomerase
- phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
- Phosphotransferase
- Glucosamine 6-phosphate N-acetyltransfera... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity), GO:0019200 (carbo... |
Q5AL03 | Hyphally regulated cell wall protein 1 | GPI-anchored hyphal cell wall protein required for hyphal growth and virulence. Involved in innate immune cell evasion through conferring resistance to neutrophil killing. Binds kininogen, the proteinaceous kinin precursor, and contributes to trigger the kinin- forming cascade on the cell surface. Production of kinins ... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 919 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor | MKVVSNFIFTILLTLNLSAALEVVTSRIDRGGIQGFHGDVKVHSGATWAILGTTLCSFFGGLEVEKGASLFIKSDNGPVLALNVALSTLVRPVINNGVISLNSKSSTSFSNFDIGGSSFTNNGEIYLASSGLVKSTAYLYAREWTNNGLIVAYQNQKAAGNIAFGTAYQTITNNGQICLRHQDFVPATKIKGTGCVTADEDTWIKLGNTILSVEPTHNFYLKDSKSSLIVHAVSSNQTFTVHGFGNGNKLGLTLPLTGNRDHFRFEYYPDTGILQLRAAALPQYFKIGKGYDSKLFRIVNSRGLKNAVTYDGPVPNNEIP... | [
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0009987",
"GO:0030682",
"GO:0042710",
"GO:0043207",
"GO:0044010",
"GO:0044011",
"GO:0044403",
"GO:0044406",
"GO:0044407",
"GO:0044419",
"GO:0050896",
"GO:0051701",
"GO:0051703",
"GO:0051707",
"GO:0052200",
"GO:0075136",
"GO:0090605"... | [
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0009987",
"GO:0030682",
"GO:0042710",
"GO:0043207",
"GO:0044010",
"GO:0044011",
"GO:0044403",
"GO:0044406",
"GO:0044407",
"GO:0044419",
"GO:0050896",
"GO:0051701",
"GO:0051703",
"GO:0051707",
"GO:0052200",
"GO:0075136",
"GO:0090605"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0030984",
"GO:0030985"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030446",
"GO:0071944",
"GO:0110165"
] | AF-Q5AL03-F1-model_v6.pdb | {"IPR021031": [12, 334]} | - IPR021031: Hyphally-regulated cell wall protein, N-terminal (domain) [12-334] | - Agglutinin-like protein 3
- Hyphal wall protein 1
- Extent of cell elongation protein 1
- Enhanced filamentous growth protein 1
- Cell wall protein RBT1
- Agglutinin-like protein 1
- Secreted aspartic protease 4
- Hypha-specific G1 cyclin-related protein 1
- Hyphal wall protein 2
- GPI-anchored hemophore RBT5 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098743 (cell aggregation), GO:0031589 (cell-substrate adhesion), GO:0098630 (aggregation o... |
Q5A029 | Cell wall protein IFF3 | GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 941 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor | MQLFQNILVSIALLTQVVFAIEITENKVDRGTVTLNLSDITIYPGASWSIIDNAYTSFVGKLDVRDGAGLYISSTSHLLALQVSLTALLHSITNNGVVSFDSRISRTSSSYDLRGVSFTNNGEMYFAASGEFSSSTALTSASWTNTRLLSFYQNQRTSGTVSLGMPLGSITNNGQVCLNNQVYEQTTQIKGSGCFTANGDSTIYISNVLLAVSPKQNFYLTDKGSSMIVQAVSTTQTFNVYGFGEGNKIGLTIPLMGNLWNSAYAYDTTSGILTLRNLLLEQKFNIGTGYDPSKFQVVTDSGSGIPSTILGSVAYYGRVP... | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q5A029-F1-model_v6.pdb | {"IPR021031": [12, 339], "IPR031573": [578, 693]} | - IPR031573: GPI-anchored cell wall protein repeat (repeat) [578-693]
- IPR021031: Hyphally-regulated cell wall protein, N-terminal (domain) [12-339] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0031589 (cell-substrate adhesion)
Cellular Component (CC): GO:0005575 (cellular component),... | |
Q59XL0 | Cell wall protein IFF6 | GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,085 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor | MLLKQIFLPFFVLFNAINAIDIYQNQVSRGTIDLSIGAITIHSGAYWSIIDNAISALVGTLTVQQDAGFYITGLNPLLGLQVELLGVLNSIKNDGIVSFNGLNSLVGPIYNLVGLSFQNNGEFYLSASGVAPPVFSITAADWHNNGLLVLAQAKRTSALANLGFPTGSIENQGSICLFGTAYQQLTSITGSGCISADRDSTIYIFSSLLPIATTQTLYLADRASSIVIQPVTLPATYTVRGFGNGNKVGISLPLLSVPLLGQPAYSYDPSSGVLTLRGLGVGLLSQRFQIGTGYDSSLLEIVTDDGAGLPTTLLGSVRYN... | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q59XL0-F1-model_v6.pdb | {"IPR021031": [11, 341]} | - IPR021031: Hyphally-regulated cell wall protein, N-terminal (domain) [11-341] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhe... | |
Q59XB0 | Cell wall protein IFF7 | GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 714 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor | MLFTLSILSTLLFSTSISAIEITQNRVDHGTITTSIGDITIDSGAYWSIIDNSISTFIGNLDIKSNAGLYISSTISNLPLLVLLNSGSASITNDGIVSLDARTSTQGSSQFNLVGGSFENNGEFYLAASGAIPMTMGLTGKSWNNNGLIVAYQNERSSGSVKFGVIGQTITNKGQICLTNQVYQQTSKIDGSGCVTAKKNASIYISNVLDPQSVSTEQNYFLADDKSSIITQAVGFNTQVINVFGFGNGNKIGLTLPLKSGNGGQAYSYDSDSGVLSLSSGLFGQKFNIGPGYDSKLFSIVTDNSEGIPSVNNGAVSYSG... | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q59XB0-F1-model_v6.pdb | {"IPR021031": [11, 343]} | - IPR021031: Hyphally-regulated cell wall protein, N-terminal (domain) [11-343] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0031589 (cell-substrate adhesion... | |
Q5A6U1 | Cell wall protein IFF9 | GPI-anchored cell wall protein involved in cell wall organization, hyphal growth, as well as in host-fungal interaction and virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 941 | Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor | MQLFQNILVSIALLTQIVFAIEITENKVDRGTVTLNLSDITIYPGASWSIIDNAYTSFVGKLDVRDGAGLYISSTSHLLALQVSLTALLHSITNNGVVSFDSRISRTSSSYDLRGVSFTNNGEMYFAASGEFSSPTALTSASWTNTGLLSFYQNQRTSGTVSLGMPLGSITNTGQVCLNNQVYEQTTQIKGSGCFTANGDSTIYISNVLLAVSPKQNFYLTDKGSSMIVQAVSTTQTFNVYGFGEGNKIGLTIPLMGNLWNSAYAYDTTSGILTLRNLLLEQKFNIGTGYDPSKFQVVTDSGSGIPSTILGSVAYYGRVP... | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q5A6U1-F1-model_v6.pdb | {"IPR021031": [12, 339], "IPR031573": [578, 693]} | - IPR031573: GPI-anchored cell wall protein repeat (repeat) [578-693]
- IPR021031: Hyphally-regulated cell wall protein, N-terminal (domain) [12-339] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0031589 (cell-substrate adhesion)
Cellular Component (CC): GO:0005575 (cellular component),... | |
Q9R002 | Interferon-activable protein 202 | DNA-binding protein involved in innate immune response and has anti-inflammatory activity. Inhibits caspase activation in response to cytosolic DNA by preventing activation of the AIM2 inflammasome, probably by sequestering cytoplasmic DNA and preventing its being bound by AIM2. Also inhibits activation of the AIM2 inf... | Mus musculus (Mouse) | 445 | Cytoplasm. Nucleus. Note=Accumulates first in the cytoplasm, and is translocated to the nucleus after a delay, where it is primarily chromatin-associated | MSNRNLRSSTNSEFSEGQHQTPSSDSSGHGEDQPQASPGPNKKSHTPKKNISKGAVLHEKPMTVMVLTATEPFNYKEGKENMFHATVATESQYYRVKVFNMDLKEKFTENKFITISKYFNSSGILEINETATVSEAAPNQIIEVPKNIIRSAKETLKISKIKELDSGTLIYGVFAVEKKKVNDKSITFKIKDNEDNIKVVWDKKQHNINYEKGDKLQLFSFHLRKGNGKPILHSGNHSFIKGEKLLKESFEGDGYHKGPKQVVALKATKLFTYDSIKSKKMFHATVATDTEFFRVMVFEENLEKKFIPGNTIALSDYFGM... | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q9R002-F1-model_v6.pdb | {"IPR012340": [46, 445], "IPR040205": [7, 249], "IPR004021": [46, 441]} | - IPR004021: HIN-200/IF120x (domain) [46-441]
- IPR040205: HIN-200 family (family) [7-249]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [46-445] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding)
Biological Process... | |
Q9JJY9 | Interleukin-22 | Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through ... | Mus musculus (Mouse) | 179 | Secreted | MAVLQKSMSFSLMGTLAASCLLLIALWAQEANALPVNTRCKLEVSNFQQPYIVNRTFMLAKEASLADNNTDVRLIGEKLFRGVSAKDQCYLMKQVLNFTLEDVLLPQSDRFQPYMQEVVPFLTKLSNQLSSCHISGDDQNIQKNVRRLKETVKKLGESGEIKAIGELDLLFMSLRNACV | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | AF-Q9JJY9-F1-model_v6.pdb | {"IPR009079": [29, 179], "IPR020453": [1, 179], "IPR020423": [84, 104]} | - IPR020453: Interleukin-22 (family) [1-179]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [29-179]
- IPR020423: Interleukin-10, conserved site (conserved_site) [84-104] | - Interleukin-22 receptor subunit alpha-1
- Interleukin-10 receptor subunit beta
- Interleukin-22 receptor subunit alpha-2
- Interleukin-22b
- Interleukin-17A
- Interleukin-23 receptor
- Interleukin-20 receptor subunit alpha
- Interleukin-17F
- Interleukin-10
- Interferon gamma | Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (s... |
Q5BIV4 | Mitochondrial ATP-independent inner membrane protease subunit 1b | Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space | Arabidopsis thaliana (Mouse-ear cress) | 169 | Mitochondrion inner membrane | MTSPSSSFWNTASREAMKSGMFVAKVYCFLHVTTNYLGFMAYAYGPSMIPTLHPSGNMLLAERISKRYQKPSRGDIVVIRSPENPNKTPIKRVVGVEGDCISFVIDPVKSDESQTIVVPKGHVFVQGDYTHNSRDSRNFGPVPYGLIQGRVLWRVWPFQDFGPLGPTPT | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5BIV4-F1-model_v6.pdb | {"IPR036286": [36, 164], "IPR052064": [9, 167], "IPR000223": [33, 137], "IPR019533": [27, 156]} | - IPR000223: Peptidase S26A, signal peptidase I (family) [33-137]
- IPR052064: Mitochondrial Inner Membrane Protease Subunit 1 (family) [9-167]
- IPR019533: Peptidase S26 (domain) [27-156]
- IPR036286: LexA/Signal peptidase-like superfamily (homologous_superfamily) [36-164] | - Mitochondrial inner membrane protease ATP23
- Mitochondrial ATP-independent inner membrane protease subunit 1a
- Peptidase S24/S26A/S26B/S26C family protein
- Mitochondrial metalloendopeptidase OMA1
- Pectin lyase-like superfamily protein
- Cyanate hydratase
- Pectin lyase-like superfamily protein
- endo-polygalactur... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (met... |
Q59KI4 | Chromatin-remodeling ATPase INO80 | ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,387 | Nucleus | MNISSMLSSDNNVSLKESMTTATDQQQQQQAESVDHASINGNGQTSVSAVNNVQENHLSEFHSSNQQHSSIPPVGTTVEHATTTTTTATNHQPVNSSPLKHSVDENSNPTTISSLKKDTNSIIASILPESYQFDNSYTPTIDQKYKSVFESNINVINQLDQYQQMGHHLKLMKFDEVKLNNYLINTGQFASNYIDRVVAEDISSRNNKISETNKNKELIAIDYSKPLHHNSTRGKEFKWGSTRKIHKVEHKSRRRKPAATTSTTDDSNKAVAAAANGTKDHSATAGTTASANGSDTPDRRHQRQSSKPSTPILIKPKTEP... | [
"GO:0008150",
"GO:0010570",
"GO:0040008",
"GO:0045927",
"GO:0048518",
"GO:0050789",
"GO:0065007",
"GO:0090033",
"GO:1900428",
"GO:1900430",
"GO:0000228",
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005694",
"GO:0031011",
"GO:0031974",
"GO:0031981",
"GO:0032991"... | [
"GO:0008150",
"GO:0010570",
"GO:0040008",
"GO:0045927",
"GO:0048518",
"GO:0050789",
"GO:0065007",
"GO:0090033",
"GO:1900428",
"GO:1900430"
] | [] | [
"GO:0000228",
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005694",
"GO:0031011",
"GO:0031974",
"GO:0031981",
"GO:0032991",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0043233",
"GO:0070013",
"GO:0070603",
"GO:0097346"... | AF-Q59KI4-F1-model_v6.pdb | {"IPR038718": [643, 922], "IPR027417": [647, 1387], "IPR050520": [602, 1050], "IPR020838": [432, 564], "IPR014001": [668, 867], "IPR000330": [675, 974], "IPR049730": [1235, 1360], "IPR001650": [1237, 1387]} | - IPR038718: SNF2-like, N-terminal domain superfamily (homologous_superfamily) [643-922]
- IPR020838: DBINO domain (domain) [432-564]
- IPR001650: Helicase, C-terminal domain-like (domain) [1237-1387]
- IPR050520: INO80/SWR1 chromatin remodeling helicase (family) [602-1050]
- IPR014001: Helicase superfamily 1/2, ATP-bi... | - Arp8p
- RuvB-like helicase 1
- RuvB-like helicase 2
- Actin-related protein 4
- HMG box domain-containing protein
- Actin-related protein 5
- Actin
- Vps72/YL1 C-terminal domain-containing protein
- Ino eighty subunit 1
- TATA-binding protein-associated factor | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0008094 (ATP-dependent activity, acting on DNA), GO:0016787 (hydrolase activity), GO:0016817... |
Q5AH02 | Ras GTPase-activating-like protein IQG1 | Required for the assembly and the contraction of the actomyosin ring at the bud neck during cytokinesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,647 | Bud neck. Note=Forms a ring at the bud neck in a MLC1-dependent manner, which contracts at the end of cytokinesis | MAIGNIAARYLSSLEETDTTATTTTTTTSNVLQPSNRLNSPTKFNRKSLDNNSQDLDALARALNITPSKPETPTSISKGSATSLLRTKFESPSATVSSFKSTSSSNGVSPTKKNHFVEITSDETPSWANKNYKDILNKSPTKFNTQSNVHTPLKQLNQPIGTPSSSSLSPAKNASKSSPGYEYLCRIEAIKQWLESVLQEQITQSASQLISYIRNGIHLAKLANVVLPTSKPVFLNDSKLQFKHTENINRFFQLLDFFNMPDLFRFELTDLYDAKNVPKVWFCLHALSYILHKQDPSYPAMNNLVGKVDFSADDIRTANR... | [
"GO:0000910",
"GO:0000912",
"GO:0000915",
"GO:0006996",
"GO:0007010",
"GO:0007049",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0022607",
"GO:0030029",
"GO:0030036",
"GO:0030865",
"GO:0030866",
"GO:0031032",
"GO:0032506",
"GO:0044085",
"GO:0044837",
"GO:0051301"... | [
"GO:0000910",
"GO:0000912",
"GO:0000915",
"GO:0006996",
"GO:0007010",
"GO:0007049",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0022607",
"GO:0030029",
"GO:0030036",
"GO:0030865",
"GO:0030866",
"GO:0031032",
"GO:0032506",
"GO:0044085",
"GO:0044837",
"GO:0051301"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0008092"
] | [
"GO:0000142",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005826",
"GO:0005856",
"GO:0005933",
"GO:0005935",
"GO:0005938",
"GO:0015629",
"GO:0030427",
"GO:0030863",
"GO:0030864",
"GO:0032153",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0070938",
"GO:0071944"... | AF-Q5AH02-F1-model_v6.pdb | {"IPR036872": [172, 330], "IPR008936": [902, 1298], "IPR001715": [184, 291], "IPR001936": [979, 1193], "IPR000593": [1413, 1563]} | - IPR001715: Calponin homology domain (domain) [184-291]
- IPR000593: RasGAP protein, C-terminal (domain) [1413-1563]
- IPR001936: Ras GTPase-activating domain (domain) [979-1193]
- IPR036872: CH domain superfamily (homologous_superfamily) [172-330]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [9... | - Rga2p
- Myosin 1
- Formin-binding protein
- Mlc1p
- Cell division control protein 42 homolog
- Cell division control protein 42 homolog
- Inn1p
- Actin
- Cyk3p
- Formin BNR1 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:... |
Q90Y57 | Protein jagged-1a | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling (By similarity). Seems to be involved in cell-fate decisions | Danio rerio (Zebrafish) (Brachydanio rerio) | 1,242 | Membrane; Single-pass type I membrane protein. Cell membrane | MILRPSATFAALSAHVLLRCLWMRVCEASGHFEMQVLSMQNVNGELQSGACCDGARDPAERSCAADQCDTFFRVCLKEYQSRVSSGGPCSYGSGSTPVIGGNTFSVKPLDQTNDKTRIVLPFSFAWPRSYTLIVEALDFNNDSSTGSINGQVIEKAVQSGMINPNRQWQVLKHNGPVAQFQYQIRVTCDEHYFGFGCNKFCRPRDDFFGHYTCDHNGNKTCLEGWAGPECNTAICKQGCSIEHGSCKVPGNCRCLYGWQGEYCDQCIPHPGCVHGTCIEPWQCLCDTNWGGQLCDKDLNTCGTLQPCLNGGTCSNTGPDK... | [
"GO:0003674",
"GO:0005102",
"GO:0005488",
"GO:0005515",
"GO:0030545",
"GO:0030546",
"GO:0048018",
"GO:0098772",
"GO:0140677",
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0005102",
"GO:0005488",
"GO:0005515",
"GO:0030545",
"GO:0030546",
"GO:0048018",
"GO:0098772",
"GO:0140677"
] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q90Y57-F1-model_v6.pdb | {"IPR009030": [341, 789], "IPR026219": [927, 1093], "IPR011651": [29, 186], "IPR001774": [168, 232], "IPR000742": [231, 859], "IPR001881": [297, 859], "IPR001007": [866, 934], "IPR056986": [952, 1059], "IPR018097": [488, 847], "IPR013032": [717, 852], "IPR000152": [390, 849]} | - IPR000742: EGF-like domain (domain) [231-859]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [488-847]
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [390-849]
- IPR056986: Protein jagged-1/2, predicted ferredoxin-like domain (domain) [952-1059]
- IPR001774: Delta/Serrate/... | - Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 2 precursor
- Hairy/enhancer-of-split related with YRPW motif protein 1
- Protein jagged-1b
- Hairy/enhancer-of-split related with YRPW motif protein 2
- Transcription factor HES-5
- Catenin beta-1
- Vascular endothelial growth factor r... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005112 (Notch binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multi... |
P0AB74 | D-tagatose-1,6-bisphosphate aldolase subunit KbaY | Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires KbaZ subunit for full activity and stability | Escherichia coli (strain K12) | 286 | MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0051259",
"GO:0051260",
"GO:0051262",
"GO:0051289",
"GO:0065003",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0051259",
"GO:0051260",
"GO:0051262",
"GO:0051289",
"GO:0065003",
"GO:0071840"
] | [] | [] | AF-P0AB74-F1-model_v6.pdb | {"IPR013785": [1, 286], "IPR000771": [1, 284], "IPR023788": [1, 286], "IPR011288": [3, 284], "IPR050246": [4, 282]} | - IPR050246: Class II Fructose-bisphosphate Aldolase (family) [4-282]
- IPR011288: D-tagatose-bisphosphate aldolase, class II, subunit KbaY/GatY (family) [3-284]
- IPR000771: Fructose-bisphosphate aldolase, class-II (family) [1-284]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [1-286]
- IPR023788: D-t... | - D-tagatose-1,6-bisphosphate aldolase subunit KbaZ
- D-tagatose-1,6-bisphosphate aldolase subunit KbaZ
- Putative D-galactosamine-6-phosphate deaminase AgaS
- ATP-dependent 6-phosphofructokinase isozyme 1
- D-tagatose-1,6-bisphosphate aldolase subunit GatZ
- D-tagatose-1,6-bisphosphate aldolase subunit GatZ
- ATP-depe... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0043169 (cation binding), GO:0016832 (aldehyde-lyase activity), GO:0046872 (... | |
A8MYU2 | Potassium channel subfamily U member 1 | Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. The channel underlies a pH-triggered membrane hyperpolarization during the process of sperm capacitation, as sperm encounter the alkaline environment ... | Homo sapiens (Human) | 1,149 | Cell membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein | MFQTKLRNETWEDLPKMSCTTEIQAAFILSSFVTFFSGLIILLIFRLIWRSVKKWQIIKGTGIILELFTSGTIARSHVRSLHFQGQFRDHIEMLLSAQTFVGQVLVILVFVLSIGSLIIYFINSADPVGSCSSYEDKTIPIDLVFNAFFSFYFGLRFMAADDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPQILQILRAIKTSNSVKFSKLLSIILSTWFTAAGFIHLVENSGDPWLKGRNSQNISYFESIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTLGSLILFANYIPEMVELFANKRK... | [
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006813",
"GO:0008150",
"GO:0009987",
"GO:0022414",
"GO:0030001",
"GO:0034220",
"GO:0051179",
"GO:0051234",
"GO:0055085",
"GO:0071805",
"GO:0098655",
"GO:0003674",
"GO:0005215",
"GO:0005216",
"GO:0005261",
"GO:0005267",
"GO:0008324"... | [
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006813",
"GO:0008150",
"GO:0009987",
"GO:0022414",
"GO:0030001",
"GO:0034220",
"GO:0051179",
"GO:0051234",
"GO:0055085",
"GO:0071805",
"GO:0098655"
] | [
"GO:0003674",
"GO:0005215",
"GO:0005216",
"GO:0005261",
"GO:0005267",
"GO:0008324",
"GO:0015075",
"GO:0015079",
"GO:0015267",
"GO:0022803",
"GO:0022857",
"GO:0046873"
] | [] | AF-A8MYU2-F1-model_v6.pdb | {"IPR047871": [16, 1051], "IPR005821": [106, 322], "IPR003148": [330, 884], "IPR003929": [470, 557], "IPR048735": [919, 1037]} | - IPR003929: Calcium-activated potassium channel BK, alpha subunit (domain) [470-557]
- IPR047871: Calcium-activated potassium channel slowpoke-like (family) [16-1051]
- IPR005821: Ion transport domain (domain) [106-322]
- IPR048735: Ca2+-activated K+ channel Slowpoke-like, C-terminal domain (domain) [919-1037]
- IPR00... | - Calcium-activated potassium channel subunit beta-4
- Small conductance calcium-activated potassium channel protein 1
- Intermediate conductance calcium-activated potassium channel protein 4
- Calcium-activated potassium channel subunit beta-1
- Small conductance calcium-activated potassium channel protein 2
- Small c... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:19... |
Q59RQ2 | 3-ketodihydrosphingosine reductase TSC10 | Catalyzes the reduction of 3'-oxosphinganine (3- ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 310 | Endoplasmic reticulum membrane; Single-pass membrane protein | MWFSKTNFPVEGKTALIVGASQGIGVNLAERLYEKNCSTILVARTESKLQHQIQNIKEKYPESSAKISYAVADVSNYDECTRLWRTIDPADPDILFCCAGSSIPKLFQDLTKVDIESGIDINYKTVINVVHTGFKHALSNNTDNLEPHNFKKRSVVLFSSVVSFFPFIGYSQYAPMKSAIESLSIILRQELSPYNYRVTCVFPGNFQSEGFEEEQKTKPDITKKIEGPSNPIPGDECARLIIDQLDKGYDSITTDFIGWFLGCSVLGISSPRQWGFFQILVSFIVSLIAPIANWFINRDIKNSFKKTKKE | [
"GO:0006629",
"GO:0006643",
"GO:0006665",
"GO:0006666",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0030148",
"GO:0042180",
"GO:0044238",
"GO:0046467",
"GO:0046519",
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0047560"... | [
"GO:0006629",
"GO:0006643",
"GO:0006665",
"GO:0006666",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0030148",
"GO:0042180",
"GO:0044238",
"GO:0046467",
"GO:0046519"
] | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0047560"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0012505",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q59RQ2-F1-model_v6.pdb | {"IPR036291": [6, 269], "IPR045022": [12, 258], "IPR002347": [13, 217]} | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [6-269]
- IPR045022: 3-ketodihydrosphingosine reductase KDSR-like (family) [12-258]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [13-217] | - serine C-palmitoyltransferase
- Serine C-palmitoyltransferase
- Sphingolipid delta(4)-desaturase
- Lac1p
- Alkaline dihydroceramidase
- Sphingosine hydroxylase
- Sphingosine N-acyltransferase
- Sphinganine kinase
- Sphinganine kinase
- Utp5p | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (B... |
Q55GK8 | Membrane-associated sulfotransferase kil1 | Sulfotransferase involved in intracellular killing of bacteria | Dictyostelium discoideum (Social amoeba) | 471 | Membrane; Single-pass type II membrane protein | MSTTSMILTKKNIIILSIIIITIIAYQFYITSPQSFPSSNTITNTINTSGKGLDYTELLNLQKDLKAQQTEIRKQLEQLKYSINDINQNQNENQNQINNEYNNNKLNDEQENNNNNNYNNNNNNNNNELINYKERIKKKSKEQPNTCIPVEGKLLCLPNFIVIGTMKSGTTFLDYYLQKHPQIAHHSKKEIWYFNSYYANGIEWYAKHFEQYTSLENQKLIGEATPFYINNPNTAPRLFTTLKNAKLILLLRDPVERSLSQYHFSIQWLKRNKSPPLEYSFEHLIHEEADVIETCIRGHERYKEAFKQRKEIEKNGGGGL... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005794",
"GO:0012505",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005794",
"GO:0012505",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q55GK8-F1-model_v6.pdb | {"IPR027417": [132, 470], "IPR037359": [9, 470], "IPR000863": [158, 422]} | - IPR000863: Sulfotransferase domain (domain) [158-422]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [132-470]
- IPR037359: Heparan sulfate sulfotransferase (family) [9-470] | - Intermembrane lipid transfer protein vps13F
- Putative phagocytic receptor 1a
- Integrin beta-like protein A
- Glycosyltransferase
- Large ribosomal subunit protein eL15
- Putative lysozyme-like protein
- Lysozyme A
- Putative phagocytic receptor 1b | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0008146 (sulfotransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic ... |
A2QK65 | O-methyltransferase kntB | Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin kotanin. The non-reducing polyketide synthase ktnS first catalyzes the formation of the pentaketidic 4,7- dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules. Further O- methylati... | Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) | 413 | MTYPEEIDEYSLIQNGLKSLNEAAQRCQQTKHSSQDSSIEGCSARQSARDELVLEALKFLQIAQGPIDAAATCYERTAHLASVRALLEMGVFEALPTGRVSRRTEELARELNVDESLLARLLRNSSLYGPFEETGPGQYRHTPFSEAYLRPEIRGMFRFAMDDHMPAHLKLHEFLQRNGWQEPSSTTDNPYTYAHKTNGKSMFDNLSEKPERMKAFNNGMTVQAMTPLWMIDLFPWRSLAQLKPTAGQVLAVDIGGGKGKAISRIRSFCNGLPGRYILQDQEHVVKSVEGSLDPSIERMAYNFFTEQPIRGAVTYLIRRC... | [
"GO:0003674",
"GO:0003824",
"GO:0008168",
"GO:0008171",
"GO:0016740",
"GO:0016741"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0008168",
"GO:0008171",
"GO:0016740",
"GO:0016741"
] | [] | AF-A2QK65-F1-model_v6.pdb | {"IPR036388": [69, 156], "IPR036390": [76, 148], "IPR029063": [154, 411], "IPR016461": [71, 412], "IPR012967": [83, 150], "IPR001077": [195, 392]} | - IPR016461: O-methyltransferase-like (family) [71-412]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [69-156]
- IPR012967: O-methyltransferase, dimerisation domain (domain) [83-150]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [76-148]
- IPR... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008171 (O-methyltransferase activity)
Biological Process (BP): GO:0008150 (biologi... | ||
A2QK67 | Bicoumarin synthase ktnC | Non-reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the bicoumarin kotanin. The non-reducing polyketide synthase ktnS first catalyzes the formation of the pentaketidic 4,7- dihydroxy-5-methylcoumarin from acetyl coenzyme A and 4 malonyl coenzyme A molecules. Further O- methylati... | Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) | 420 | MHKSAALSLRDAQFADMNMYCDVTDRTPIEAVHSCNNAESLNILNKLLARETDTALSQIFEQPTGKDWKELNTLQTILSLCSTVTMALLLGPDTAPDPVLHHHSTSFGEAIMSSCYRRTGYPRILRPFVWRFSSECRNLRKHFSLVRERLVPEVARRVAAARAADKTKDVRPSSLLDALIAAAFDNGSLSPDDQGRNDAAQVQLLADDLIFYHFELCKPTAFNIIFQLYAIMDHPEYKAPLREEALQALKLTNGDWTVETLKHAPKLESFTKETFRLYDISGFVSFRRVMKPLTLNSIGLSLRPGTILLSPCRNVHLDPE... | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491"
] | [] | AF-A2QK67-F1-model_v6.pdb | {"IPR036396": [27, 419], "IPR001128": [150, 391], "IPR002403": [264, 380]} | - IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [27-419]
- IPR001128: Cytochrome P450 (family) [150-391]
- IPR002403: Cytochrome P450, E-class, group IV (family) [264-380] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process),... | ||
Q96BZ8 | Leukocyte receptor cluster member 1 | Homo sapiens (Human) | 264 | MNILPKKSWHVRNKDNVARVRRDEAQAREEEKERERRVLLAQQEARTEFLRKKARHQNSLPELEAAEAGAPGSGPVDLFRELLEEGKGVIRGNKEYKEEKRQEKERQEKALGILTYLGQSAAEAQTQPPWYQLPPGRGGPPPGPAPDEKIKSRLDPLREMQKHLGKKRQHGGDEGSRSRKEKEGSEKQRPKEPPSLDQLRAERLRREAAERSRAEALLARVQGRALQEGQPEEDETDDRRRRYNSQFNPQLARRPRQQDPHLTH | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q96BZ8-F1-model_v6.pdb | {"IPR039875": [1, 259], "IPR019339": [8, 44]} | - IPR039875: Leukocyte receptor cluster member 1-like (family) [1-259]
- IPR019339: CBF1-interacting co-repressor CIR, N-terminal domain (domain) [8-44] | - Peptidyl-prolyl cis-trans isomerase-like 1
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor SYF2
- Pre-mRNA-splicing factor SLU7
- Tuftelin-interacting protein 11 | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | ||
Q9P8V9 | Lipase 8 | Secreted lipase that is able to hydrolyze both the neutral triacylglycerols and the monopalmitate ester Tween 40, allowing the use of hydrolyzed products as carbon sources. Acts as an important virulence factor in mouse infection models. Has broad lipolytic activity, which may be important for colonization and subseque... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 460 | Secreted | MLFLLFLLITPIYAGLIFLTKPSNDPFYNPPKGFEKAAVGDILQSRETPKSITGRFAPLEIQNSWQLLVRSEDSFGNPNAIVTTVIQPFNADPSKVASYQVFEDSAKGDCAPSYALQFGSDLSTLATQAETFLLAPLLEQGYYVVSPDYEGPKSTFTIGKQSGQAVLNSIRAALKSGKITNIKDDAKVVMWGYSGGSLASGWAAALQPSYAPELGGNLLGAALGGFVTNITATAQAADGTVFAGIVANALGGVANEYPEFKSILQSDTDKKSVFDEFDSHCLADGVIDYINTSFLTGDNKIFKTGWDILKSSTIAKIVKD... | [
"GO:0003674",
"GO:0003824",
"GO:0016298",
"GO:0016787",
"GO:0016788"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016298",
"GO:0016787",
"GO:0016788"
] | [] | AF-Q9P8V9-F1-model_v6.pdb | {"IPR029058": [22, 399], "IPR005152": [1, 441]} | - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [22-399]
- IPR005152: Lipase, secreted (family) [1-441] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), G... | |
Q8NHZ7 | Methyl-CpG-binding domain protein 3-like 2 | May displace the NuRD complex from chromatin | Homo sapiens (Human) | 208 | Nucleus | MGEPAFTSFPSLPVLGKLKRNMMPWALQKKREIHMAKAHRRRAARSALPMRLTSCIFRRPVTRIRSHPDNQVRRRKGDEHLEKPQQLCAYRRLQALQPCSSQGEGSSPLHLESVLSILAPGTAGESLDRAGAERVRSPLEPTPGRFPAVAGGPTPGMGCQLPPPLSGQLVTPADIRRQARRVKKARERLAKALQADRLARRAEMLTGG | [
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0050789",
"GO:0050794",
"GO:0051128",
"GO:0051252",
"GO:0060255",
"GO:0065007",
"GO:0080090",
"GO:1902275",
"GO:2001141",
"GO:0005575",
"GO:0005622",
"GO:0005634"... | [
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0050789",
"GO:0050794",
"GO:0051128",
"GO:0051252",
"GO:0060255",
"GO:0065007",
"GO:0080090",
"GO:1902275",
"GO:2001141"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8NHZ7-F1-model_v6.pdb | {"IPR032343": [28, 97], "IPR025884": [103, 193]} | - IPR025884: Methyl-CpG binding protein 2/3, C-terminal domain (domain) [103-193]
- IPR032343: Methyl-CpG-binding domain protein 2/3, p55-binding region (domain) [28-97] | - Methyl-CpG-binding domain protein 3-like 3
- Tripartite motif-containing protein 43
- Paired-like homeodomain transcription factor LEUTX
- Acrosomal protein SP-10
- Zinc finger and SCAN domain-containing protein 4
- Dolichol-phosphate mannosyltransferase subunit 1
- PRAME family member 15
- PRAME family member 9
- Me... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (po... |
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