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README.md
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# A Single-Cell Transcriptomic Atlas of Human Skin Aging
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This dataset contains structured tables extracted from the supplementary materials of the publication:
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> **"A single-cell transcriptomic atlas of human skin aging"**
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> *Cell Reports, 2020*
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> DOI: [10.1016/j.celrep.2020.108132](https://doi.org/10.1016/j.celrep.2020.108132)
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The data has been processed from the publication PDF into a `.parquet` file to facilitate downstream analysis and integration into machine learning workflows.
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---
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## 📦 Dataset Description
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The dataset includes multiple tables capturing aging-related transcriptomic changes in human skin tissue at the single-cell level. Tables were extracted using PDF parsing tools and contain gene expression summaries and annotations useful for skin biology and aging research.
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---
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## 🔧 Usage Instructions
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To load the Parquet file in Python:
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```python
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import pandas as pd
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df = pd.read_parquet("skin_aging_data.parquet")
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print(df.head())
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```
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---
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## 🚀 Use Cases
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- Aging biomarker discovery in dermal and epidermal compartments
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- Training skin-specific biological age predictors
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- Integrating skin aging profiles with other tissue atlases
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- Cross-species comparison of skin aging signatures
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- Evaluation of anti-aging interventions at single-cell resolution
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---
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## 📖 Citation
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If you use this dataset, please cite:
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**Xie, W., et al.** *A single-cell transcriptomic atlas of human skin aging*. Cell Reports, 2020.
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DOI: [10.1016/j.celrep.2020.108132](https://doi.org/10.1016/j.celrep.2020.108132)
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---
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## 🙏 Acknowledgments
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This dataset was curated and converted by **Iris Lee** for open access machine learning research in aging biology and skin regeneration. ### 🧑💻 Team: MultiModalMillenials. Iris Lee (`@iris8090`)
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Source publication by Xie et al. (2020) — Cell Reports.
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