Iris8090 commited on
Commit
d63ba67
·
verified ·
1 Parent(s): 133f4d0

Create README.md

Browse files
Files changed (1) hide show
  1. README.md +55 -0
README.md ADDED
@@ -0,0 +1,55 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ # A Single-Cell Transcriptomic Atlas of Human Skin Aging
2
+
3
+ This dataset contains structured tables extracted from the supplementary materials of the publication:
4
+
5
+ > **"A single-cell transcriptomic atlas of human skin aging"**
6
+ > *Cell Reports, 2020*
7
+ > DOI: [10.1016/j.celrep.2020.108132](https://doi.org/10.1016/j.celrep.2020.108132)
8
+
9
+ The data has been processed from the publication PDF into a `.parquet` file to facilitate downstream analysis and integration into machine learning workflows.
10
+
11
+ ---
12
+
13
+ ## 📦 Dataset Description
14
+
15
+ The dataset includes multiple tables capturing aging-related transcriptomic changes in human skin tissue at the single-cell level. Tables were extracted using PDF parsing tools and contain gene expression summaries and annotations useful for skin biology and aging research.
16
+
17
+ ---
18
+
19
+ ## 🔧 Usage Instructions
20
+
21
+ To load the Parquet file in Python:
22
+
23
+ ```python
24
+ import pandas as pd
25
+
26
+ df = pd.read_parquet("skin_aging_data.parquet")
27
+ print(df.head())
28
+ ```
29
+
30
+ ---
31
+
32
+ ## 🚀 Use Cases
33
+
34
+ - Aging biomarker discovery in dermal and epidermal compartments
35
+ - Training skin-specific biological age predictors
36
+ - Integrating skin aging profiles with other tissue atlases
37
+ - Cross-species comparison of skin aging signatures
38
+ - Evaluation of anti-aging interventions at single-cell resolution
39
+
40
+ ---
41
+
42
+ ## 📖 Citation
43
+
44
+ If you use this dataset, please cite:
45
+
46
+ **Xie, W., et al.** *A single-cell transcriptomic atlas of human skin aging*. Cell Reports, 2020.
47
+ DOI: [10.1016/j.celrep.2020.108132](https://doi.org/10.1016/j.celrep.2020.108132)
48
+
49
+ ---
50
+
51
+ ## 🙏 Acknowledgments
52
+
53
+ This dataset was curated and converted by **Iris Lee** for open access machine learning research in aging biology and skin regeneration. ### 🧑‍💻 Team: MultiModalMillenials. Iris Lee (`@iris8090`)
54
+
55
+ Source publication by Xie et al. (2020) — Cell Reports.