Iris8090 commited on
Commit
82e59f1
·
verified ·
1 Parent(s): 2b85780

Create README.md

Browse files
Files changed (1) hide show
  1. README.md +58 -0
README.md ADDED
@@ -0,0 +1,58 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+
2
+ # 🧬 Smulders Longevity Extracted Dataset
3
+
4
+ This dataset was extracted from the publication:
5
+
6
+ > **Genetics of human longevity: From variants to genes to pathways**
7
+ > *Journal of Internal Medicine, 2023 — Smulders et al.*
8
+ > DOI: [10.1111/joim.13690](https://doi.org/10.1111/joim.13690)
9
+
10
+ It contains structured gene names and SNP identifiers mentioned throughout the paper.
11
+
12
+ ---
13
+
14
+ ## 📄 Dataset Description
15
+
16
+ | Column | Description |
17
+ |--------|------------------------------|
18
+ | type | Entry type: `Gene` or `SNP` |
19
+ | id | The gene name or SNP ID |
20
+
21
+ The gene names are uppercase identifiers, and SNPs follow the common `rs` format (e.g., rs429358).
22
+
23
+ ---
24
+
25
+ ## 🔧 Usage Instructions
26
+
27
+ ### Load in Python
28
+
29
+ ```python
30
+ import pandas as pd
31
+
32
+ df = pd.read_parquet("smulders_longevity_extracted.parquet")
33
+ print(df.head())
34
+ ```
35
+
36
+ ---
37
+
38
+ ## 🚀 Use Cases
39
+
40
+ - Gene prioritization for longevity research
41
+ - Mapping SNPs from literature to existing aging gene databases
42
+ - Input for polygenic risk score (PRS) modeling
43
+ - Enhancing datasets like LongevityMap with literature-derived signals
44
+
45
+ ---
46
+
47
+ ## 📚 Citation
48
+
49
+ If you use this dataset, please cite the original paper:
50
+
51
+ > Smulders, Y. M., et al. (2023). Genetics of human longevity: From variants to genes to pathways. *Journal of Internal Medicine*.
52
+ > [https://doi.org/10.1111/joim.13690](https://doi.org/10.1111/joim.13690)
53
+
54
+ ---
55
+
56
+ ## 🙏 Acknowledgments
57
+
58
+ Extracted and compiled by Iris Lee for longevity research and hackathon use. ### 🧑‍💻 Team: MultiModalMillenials. Iris Lee (`@iris8090`)