| data_2FLU |
| |
| _entry.id 2FLU |
| |
| _audit_conform.dict_name mmcif_pdbx.dic |
| _audit_conform.dict_version 5.398 |
| _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic |
| |
| loop_ |
| _database_2.database_id |
| _database_2.database_code |
| _database_2.pdbx_database_accession |
| _database_2.pdbx_DOI |
| PDB 2FLU pdb_00002flu 10.2210/pdb2flu/pdb |
| RCSB RCSB036033 ? ? |
| WWPDB D_1000036033 ? ? |
| |
| loop_ |
| _pdbx_audit_revision_history.ordinal |
| _pdbx_audit_revision_history.data_content_type |
| _pdbx_audit_revision_history.major_revision |
| _pdbx_audit_revision_history.minor_revision |
| _pdbx_audit_revision_history.revision_date |
| 1 'Structure model' 1 0 2006-08-15 |
| 2 'Structure model' 1 1 2008-05-01 |
| 3 'Structure model' 1 2 2011-07-13 |
| 4 'Structure model' 1 3 2023-08-30 |
| 5 'Structure model' 1 4 2024-10-30 |
| |
| _pdbx_audit_revision_details.ordinal 1 |
| _pdbx_audit_revision_details.revision_ordinal 1 |
| _pdbx_audit_revision_details.data_content_type 'Structure model' |
| _pdbx_audit_revision_details.provider repository |
| _pdbx_audit_revision_details.type 'Initial release' |
| _pdbx_audit_revision_details.description ? |
| _pdbx_audit_revision_details.details ? |
| |
| loop_ |
| _pdbx_audit_revision_group.ordinal |
| _pdbx_audit_revision_group.revision_ordinal |
| _pdbx_audit_revision_group.data_content_type |
| _pdbx_audit_revision_group.group |
| 1 2 'Structure model' 'Version format compliance' |
| 2 3 'Structure model' Advisory |
| 3 3 'Structure model' 'Version format compliance' |
| 4 4 'Structure model' 'Data collection' |
| 5 4 'Structure model' 'Database references' |
| 6 4 'Structure model' 'Refinement description' |
| 7 5 'Structure model' 'Structure summary' |
| |
| loop_ |
| _pdbx_audit_revision_category.ordinal |
| _pdbx_audit_revision_category.revision_ordinal |
| _pdbx_audit_revision_category.data_content_type |
| _pdbx_audit_revision_category.category |
| 1 4 'Structure model' chem_comp_atom |
| 2 4 'Structure model' chem_comp_bond |
| 3 4 'Structure model' database_2 |
| 4 4 'Structure model' pdbx_initial_refinement_model |
| 5 4 'Structure model' struct_ref_seq_dif |
| 6 5 'Structure model' pdbx_entry_details |
| 7 5 'Structure model' pdbx_modification_feature |
| |
| loop_ |
| _pdbx_audit_revision_item.ordinal |
| _pdbx_audit_revision_item.revision_ordinal |
| _pdbx_audit_revision_item.data_content_type |
| _pdbx_audit_revision_item.item |
| 1 4 'Structure model' '_database_2.pdbx_DOI' |
| 2 4 'Structure model' '_database_2.pdbx_database_accession' |
| 3 4 'Structure model' '_struct_ref_seq_dif.details' |
| |
| _pdbx_database_status.status_code REL |
| _pdbx_database_status.entry_id 2FLU |
| _pdbx_database_status.recvd_initial_deposition_date 2006-01-06 |
| _pdbx_database_status.deposit_site RCSB |
| _pdbx_database_status.process_site RCSB |
| _pdbx_database_status.status_code_sf REL |
| _pdbx_database_status.status_code_mr ? |
| _pdbx_database_status.SG_entry ? |
| _pdbx_database_status.pdb_format_compatible Y |
| _pdbx_database_status.status_code_cs ? |
| _pdbx_database_status.status_code_nmr_data ? |
| _pdbx_database_status.methods_development_category ? |
| |
| loop_ |
| _pdbx_database_related.db_name |
| _pdbx_database_related.db_id |
| _pdbx_database_related.details |
| _pdbx_database_related.content_type |
| PDB 1U6D 'Crystal structure of the kelch domain of human Keap1 at 1.85 A' unspecified |
| PDB 1ZGK 'Crystal structure of the kelch domain of human Keap1 at 1.35 A' unspecified |
| |
| loop_ |
| _audit_author.name |
| _audit_author.pdbx_ordinal |
| 'Li, X.' 1 |
| 'Lo, J.' 2 |
| 'Beamer, L.' 3 |
| 'Hannink, M.' 4 |
| |
| _citation.id primary |
| _citation.title 'Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.' |
| _citation.journal_abbrev 'Embo J.' |
| _citation.journal_volume 25 |
| _citation.page_first 3605 |
| _citation.page_last 3617 |
| _citation.year 2006 |
| _citation.journal_id_ASTM EMJODG |
| _citation.country UK |
| _citation.journal_id_ISSN 0261-4189 |
| _citation.journal_id_CSD 0897 |
| _citation.book_publisher ? |
| _citation.pdbx_database_id_PubMed 16888629 |
| _citation.pdbx_database_id_DOI 10.1038/sj.emboj.7601243 |
| |
| loop_ |
| _citation_author.citation_id |
| _citation_author.name |
| _citation_author.ordinal |
| _citation_author.identifier_ORCID |
| primary 'Lo, S.C.' 1 ? |
| primary 'Li, X.' 2 ? |
| primary 'Henzl, M.T.' 3 ? |
| primary 'Beamer, L.J.' 4 ? |
| primary 'Hannink, M.' 5 ? |
| |
| loop_ |
| _entity.id |
| _entity.type |
| _entity.src_method |
| _entity.pdbx_description |
| _entity.formula_weight |
| _entity.pdbx_number_of_molecules |
| _entity.pdbx_ec |
| _entity.pdbx_mutation |
| _entity.pdbx_fragment |
| _entity.details |
| 1 polymer man 'Kelch-like ECH-associated protein 1' 33694.527 1 ? ? 'Kelch domain of human Keap1' ? |
| 2 polymer syn Nrf2 1858.008 1 ? ? '16-mer peptide from huma Neh2' ? |
| 3 water nat water 18.015 333 ? ? ? ? |
| |
| loop_ |
| _entity_poly.entity_id |
| _entity_poly.type |
| _entity_poly.nstd_linkage |
| _entity_poly.nstd_monomer |
| _entity_poly.pdbx_seq_one_letter_code |
| _entity_poly.pdbx_seq_one_letter_code_can |
| _entity_poly.pdbx_strand_id |
| _entity_poly.pdbx_target_identifier |
| 1 'polypeptide(L)' no no |
| ;GSSHHHHHHSSGLVPRGSHAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRN |
| NSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRI |
| GVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVET |
| ETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT |
| ; |
| ;GSSHHHHHHSSGLVPRGSHAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRN |
| NSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRI |
| GVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVET |
| ETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT |
| ; |
| X ? |
| 2 'polypeptide(L)' no no AFFAQLQLDEETGEFL AFFAQLQLDEETGEFL P ? |
| |
| _pdbx_entity_nonpoly.entity_id 3 |
| _pdbx_entity_nonpoly.name water |
| _pdbx_entity_nonpoly.comp_id HOH |
| |
| loop_ |
| _entity_poly_seq.entity_id |
| _entity_poly_seq.num |
| _entity_poly_seq.mon_id |
| _entity_poly_seq.hetero |
| 1 1 GLY n |
| 1 2 SER n |
| 1 3 SER n |
| 1 4 HIS n |
| 1 5 HIS n |
| 1 6 HIS n |
| 1 7 HIS n |
| 1 8 HIS n |
| 1 9 HIS n |
| 1 10 SER n |
| 1 11 SER n |
| 1 12 GLY n |
| 1 13 LEU n |
| 1 14 VAL n |
| 1 15 PRO n |
| 1 16 ARG n |
| 1 17 GLY n |
| 1 18 SER n |
| 1 19 HIS n |
| 1 20 ALA n |
| 1 21 PRO n |
| 1 22 LYS n |
| 1 23 VAL n |
| 1 24 GLY n |
| 1 25 ARG n |
| 1 26 LEU n |
| 1 27 ILE n |
| 1 28 TYR n |
| 1 29 THR n |
| 1 30 ALA n |
| 1 31 GLY n |
| 1 32 GLY n |
| 1 33 TYR n |
| 1 34 PHE n |
| 1 35 ARG n |
| 1 36 GLN n |
| 1 37 SER n |
| 1 38 LEU n |
| 1 39 SER n |
| 1 40 TYR n |
| 1 41 LEU n |
| 1 42 GLU n |
| 1 43 ALA n |
| 1 44 TYR n |
| 1 45 ASN n |
| 1 46 PRO n |
| 1 47 SER n |
| 1 48 ASP n |
| 1 49 GLY n |
| 1 50 THR n |
| 1 51 TRP n |
| 1 52 LEU n |
| 1 53 ARG n |
| 1 54 LEU n |
| 1 55 ALA n |
| 1 56 ASP n |
| 1 57 LEU n |
| 1 58 GLN n |
| 1 59 VAL n |
| 1 60 PRO n |
| 1 61 ARG n |
| 1 62 SER n |
| 1 63 GLY n |
| 1 64 LEU n |
| 1 65 ALA n |
| 1 66 GLY n |
| 1 67 CYS n |
| 1 68 VAL n |
| 1 69 VAL n |
| 1 70 GLY n |
| 1 71 GLY n |
| 1 72 LEU n |
| 1 73 LEU n |
| 1 74 TYR n |
| 1 75 ALA n |
| 1 76 VAL n |
| 1 77 GLY n |
| 1 78 GLY n |
| 1 79 ARG n |
| 1 80 ASN n |
| 1 81 ASN n |
| 1 82 SER n |
| 1 83 PRO n |
| 1 84 ASP n |
| 1 85 GLY n |
| 1 86 ASN n |
| 1 87 THR n |
| 1 88 ASP n |
| 1 89 SER n |
| 1 90 SER n |
| 1 91 ALA n |
| 1 92 LEU n |
| 1 93 ASP n |
| 1 94 CYS n |
| 1 95 TYR n |
| 1 96 ASN n |
| 1 97 PRO n |
| 1 98 MET n |
| 1 99 THR n |
| 1 100 ASN n |
| 1 101 GLN n |
| 1 102 TRP n |
| 1 103 SER n |
| 1 104 PRO n |
| 1 105 CYS n |
| 1 106 ALA n |
| 1 107 PRO n |
| 1 108 MET n |
| 1 109 SER n |
| 1 110 VAL n |
| 1 111 PRO n |
| 1 112 ARG n |
| 1 113 ASN n |
| 1 114 ARG n |
| 1 115 ILE n |
| 1 116 GLY n |
| 1 117 VAL n |
| 1 118 GLY n |
| 1 119 VAL n |
| 1 120 ILE n |
| 1 121 ASP n |
| 1 122 GLY n |
| 1 123 HIS n |
| 1 124 ILE n |
| 1 125 TYR n |
| 1 126 ALA n |
| 1 127 VAL n |
| 1 128 GLY n |
| 1 129 GLY n |
| 1 130 SER n |
| 1 131 HIS n |
| 1 132 GLY n |
| 1 133 CYS n |
| 1 134 ILE n |
| 1 135 HIS n |
| 1 136 HIS n |
| 1 137 ASN n |
| 1 138 SER n |
| 1 139 VAL n |
| 1 140 GLU n |
| 1 141 ARG n |
| 1 142 TYR n |
| 1 143 GLU n |
| 1 144 PRO n |
| 1 145 GLU n |
| 1 146 ARG n |
| 1 147 ASP n |
| 1 148 GLU n |
| 1 149 TRP n |
| 1 150 HIS n |
| 1 151 LEU n |
| 1 152 VAL n |
| 1 153 ALA n |
| 1 154 PRO n |
| 1 155 MET n |
| 1 156 LEU n |
| 1 157 THR n |
| 1 158 ARG n |
| 1 159 ARG n |
| 1 160 ILE n |
| 1 161 GLY n |
| 1 162 VAL n |
| 1 163 GLY n |
| 1 164 VAL n |
| 1 165 ALA n |
| 1 166 VAL n |
| 1 167 LEU n |
| 1 168 ASN n |
| 1 169 ARG n |
| 1 170 LEU n |
| 1 171 LEU n |
| 1 172 TYR n |
| 1 173 ALA n |
| 1 174 VAL n |
| 1 175 GLY n |
| 1 176 GLY n |
| 1 177 PHE n |
| 1 178 ASP n |
| 1 179 GLY n |
| 1 180 THR n |
| 1 181 ASN n |
| 1 182 ARG n |
| 1 183 LEU n |
| 1 184 ASN n |
| 1 185 SER n |
| 1 186 ALA n |
| 1 187 GLU n |
| 1 188 CYS n |
| 1 189 TYR n |
| 1 190 TYR n |
| 1 191 PRO n |
| 1 192 GLU n |
| 1 193 ARG n |
| 1 194 ASN n |
| 1 195 GLU n |
| 1 196 TRP n |
| 1 197 ARG n |
| 1 198 MET n |
| 1 199 ILE n |
| 1 200 THR n |
| 1 201 ALA n |
| 1 202 MET n |
| 1 203 ASN n |
| 1 204 THR n |
| 1 205 ILE n |
| 1 206 ARG n |
| 1 207 SER n |
| 1 208 GLY n |
| 1 209 ALA n |
| 1 210 GLY n |
| 1 211 VAL n |
| 1 212 CYS n |
| 1 213 VAL n |
| 1 214 LEU n |
| 1 215 HIS n |
| 1 216 ASN n |
| 1 217 CYS n |
| 1 218 ILE n |
| 1 219 TYR n |
| 1 220 ALA n |
| 1 221 ALA n |
| 1 222 GLY n |
| 1 223 GLY n |
| 1 224 TYR n |
| 1 225 ASP n |
| 1 226 GLY n |
| 1 227 GLN n |
| 1 228 ASP n |
| 1 229 GLN n |
| 1 230 LEU n |
| 1 231 ASN n |
| 1 232 SER n |
| 1 233 VAL n |
| 1 234 GLU n |
| 1 235 ARG n |
| 1 236 TYR n |
| 1 237 ASP n |
| 1 238 VAL n |
| 1 239 GLU n |
| 1 240 THR n |
| 1 241 GLU n |
| 1 242 THR n |
| 1 243 TRP n |
| 1 244 THR n |
| 1 245 PHE n |
| 1 246 VAL n |
| 1 247 ALA n |
| 1 248 PRO n |
| 1 249 MET n |
| 1 250 LYS n |
| 1 251 HIS n |
| 1 252 ARG n |
| 1 253 ARG n |
| 1 254 SER n |
| 1 255 ALA n |
| 1 256 LEU n |
| 1 257 GLY n |
| 1 258 ILE n |
| 1 259 THR n |
| 1 260 VAL n |
| 1 261 HIS n |
| 1 262 GLN n |
| 1 263 GLY n |
| 1 264 ARG n |
| 1 265 ILE n |
| 1 266 TYR n |
| 1 267 VAL n |
| 1 268 LEU n |
| 1 269 GLY n |
| 1 270 GLY n |
| 1 271 TYR n |
| 1 272 ASP n |
| 1 273 GLY n |
| 1 274 HIS n |
| 1 275 THR n |
| 1 276 PHE n |
| 1 277 LEU n |
| 1 278 ASP n |
| 1 279 SER n |
| 1 280 VAL n |
| 1 281 GLU n |
| 1 282 CYS n |
| 1 283 TYR n |
| 1 284 ASP n |
| 1 285 PRO n |
| 1 286 ASP n |
| 1 287 THR n |
| 1 288 ASP n |
| 1 289 THR n |
| 1 290 TRP n |
| 1 291 SER n |
| 1 292 GLU n |
| 1 293 VAL n |
| 1 294 THR n |
| 1 295 ARG n |
| 1 296 MET n |
| 1 297 THR n |
| 1 298 SER n |
| 1 299 GLY n |
| 1 300 ARG n |
| 1 301 SER n |
| 1 302 GLY n |
| 1 303 VAL n |
| 1 304 GLY n |
| 1 305 VAL n |
| 1 306 ALA n |
| 1 307 VAL n |
| 1 308 THR n |
| 2 1 ALA n |
| 2 2 PHE n |
| 2 3 PHE n |
| 2 4 ALA n |
| 2 5 GLN n |
| 2 6 LEU n |
| 2 7 GLN n |
| 2 8 LEU n |
| 2 9 ASP n |
| 2 10 GLU n |
| 2 11 GLU n |
| 2 12 THR n |
| 2 13 GLY n |
| 2 14 GLU n |
| 2 15 PHE n |
| 2 16 LEU n |
| |
| _entity_src_gen.entity_id 1 |
| _entity_src_gen.pdbx_src_id 1 |
| _entity_src_gen.pdbx_alt_source_flag sample |
| _entity_src_gen.pdbx_seq_type ? |
| _entity_src_gen.pdbx_beg_seq_num ? |
| _entity_src_gen.pdbx_end_seq_num ? |
| _entity_src_gen.gene_src_common_name human |
| _entity_src_gen.gene_src_genus Homo |
| _entity_src_gen.pdbx_gene_src_gene ? |
| _entity_src_gen.gene_src_species ? |
| _entity_src_gen.gene_src_strain ? |
| _entity_src_gen.gene_src_tissue ? |
| _entity_src_gen.gene_src_tissue_fraction ? |
| _entity_src_gen.gene_src_details ? |
| _entity_src_gen.pdbx_gene_src_fragment ? |
| _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' |
| _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 |
| _entity_src_gen.pdbx_gene_src_variant ? |
| _entity_src_gen.pdbx_gene_src_cell_line ? |
| _entity_src_gen.pdbx_gene_src_atcc ? |
| _entity_src_gen.pdbx_gene_src_organ ? |
| _entity_src_gen.pdbx_gene_src_organelle ? |
| _entity_src_gen.pdbx_gene_src_cell ? |
| _entity_src_gen.pdbx_gene_src_cellular_location ? |
| _entity_src_gen.host_org_common_name ? |
| _entity_src_gen.pdbx_host_org_scientific_name 'Escherichia coli' |
| _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 562 |
| _entity_src_gen.host_org_genus Escherichia |
| _entity_src_gen.pdbx_host_org_gene ? |
| _entity_src_gen.pdbx_host_org_organ ? |
| _entity_src_gen.host_org_species ? |
| _entity_src_gen.pdbx_host_org_tissue ? |
| _entity_src_gen.pdbx_host_org_tissue_fraction ? |
| _entity_src_gen.pdbx_host_org_strain ? |
| _entity_src_gen.pdbx_host_org_variant ? |
| _entity_src_gen.pdbx_host_org_cell_line ? |
| _entity_src_gen.pdbx_host_org_atcc ? |
| _entity_src_gen.pdbx_host_org_culture_collection ? |
| _entity_src_gen.pdbx_host_org_cell ? |
| _entity_src_gen.pdbx_host_org_organelle ? |
| _entity_src_gen.pdbx_host_org_cellular_location ? |
| _entity_src_gen.pdbx_host_org_vector_type ? |
| _entity_src_gen.pdbx_host_org_vector ? |
| _entity_src_gen.host_org_details ? |
| _entity_src_gen.expression_system_id ? |
| _entity_src_gen.plasmid_name ? |
| _entity_src_gen.plasmid_details ? |
| _entity_src_gen.pdbx_description ? |
| |
| _pdbx_entity_src_syn.entity_id 2 |
| _pdbx_entity_src_syn.pdbx_src_id 1 |
| _pdbx_entity_src_syn.pdbx_alt_source_flag sample |
| _pdbx_entity_src_syn.pdbx_beg_seq_num ? |
| _pdbx_entity_src_syn.pdbx_end_seq_num ? |
| _pdbx_entity_src_syn.organism_scientific ? |
| _pdbx_entity_src_syn.organism_common_name ? |
| _pdbx_entity_src_syn.ncbi_taxonomy_id ? |
| _pdbx_entity_src_syn.details 'synthesized peptide' |
| |
| loop_ |
| _chem_comp.id |
| _chem_comp.type |
| _chem_comp.mon_nstd_flag |
| _chem_comp.name |
| _chem_comp.pdbx_synonyms |
| _chem_comp.formula |
| _chem_comp.formula_weight |
| ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 |
| ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 |
| ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 |
| ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 |
| CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 |
| GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 |
| GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 |
| GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 |
| HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 |
| HOH non-polymer . WATER ? 'H2 O' 18.015 |
| ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 |
| LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 |
| LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 |
| MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 |
| PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 |
| PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 |
| SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 |
| THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 |
| TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 |
| TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 |
| VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 |
| |
| loop_ |
| _pdbx_poly_seq_scheme.asym_id |
| _pdbx_poly_seq_scheme.entity_id |
| _pdbx_poly_seq_scheme.seq_id |
| _pdbx_poly_seq_scheme.mon_id |
| _pdbx_poly_seq_scheme.ndb_seq_num |
| _pdbx_poly_seq_scheme.pdb_seq_num |
| _pdbx_poly_seq_scheme.auth_seq_num |
| _pdbx_poly_seq_scheme.pdb_mon_id |
| _pdbx_poly_seq_scheme.auth_mon_id |
| _pdbx_poly_seq_scheme.pdb_strand_id |
| _pdbx_poly_seq_scheme.pdb_ins_code |
| _pdbx_poly_seq_scheme.hetero |
| A 1 1 GLY 1 302 ? ? ? X . n |
| A 1 2 SER 2 303 ? ? ? X . n |
| A 1 3 SER 3 304 ? ? ? X . n |
| A 1 4 HIS 4 305 ? ? ? X . n |
| A 1 5 HIS 5 306 ? ? ? X . n |
| A 1 6 HIS 6 307 ? ? ? X . n |
| A 1 7 HIS 7 308 ? ? ? X . n |
| A 1 8 HIS 8 309 ? ? ? X . n |
| A 1 9 HIS 9 310 ? ? ? X . n |
| A 1 10 SER 10 311 ? ? ? X . n |
| A 1 11 SER 11 312 ? ? ? X . n |
| A 1 12 GLY 12 313 ? ? ? X . n |
| A 1 13 LEU 13 314 ? ? ? X . n |
| A 1 14 VAL 14 315 ? ? ? X . n |
| A 1 15 PRO 15 316 ? ? ? X . n |
| A 1 16 ARG 16 317 ? ? ? X . n |
| A 1 17 GLY 17 318 ? ? ? X . n |
| A 1 18 SER 18 319 ? ? ? X . n |
| A 1 19 HIS 19 320 ? ? ? X . n |
| A 1 20 ALA 20 321 ? ? ? X . n |
| A 1 21 PRO 21 322 ? ? ? X . n |
| A 1 22 LYS 22 323 ? ? ? X . n |
| A 1 23 VAL 23 324 ? ? ? X . n |
| A 1 24 GLY 24 325 325 GLY GLY X . n |
| A 1 25 ARG 25 326 326 ARG ARG X . n |
| A 1 26 LEU 26 327 327 LEU LEU X . n |
| A 1 27 ILE 27 328 328 ILE ILE X . n |
| A 1 28 TYR 28 329 329 TYR TYR X . n |
| A 1 29 THR 29 330 330 THR THR X . n |
| A 1 30 ALA 30 331 331 ALA ALA X . n |
| A 1 31 GLY 31 332 332 GLY GLY X . n |
| A 1 32 GLY 32 333 333 GLY GLY X . n |
| A 1 33 TYR 33 334 334 TYR TYR X . n |
| A 1 34 PHE 34 335 335 PHE PHE X . n |
| A 1 35 ARG 35 336 336 ARG ARG X . n |
| A 1 36 GLN 36 337 337 GLN GLN X . n |
| A 1 37 SER 37 338 338 SER SER X . n |
| A 1 38 LEU 38 339 339 LEU LEU X . n |
| A 1 39 SER 39 340 340 SER SER X . n |
| A 1 40 TYR 40 341 341 TYR TYR X . n |
| A 1 41 LEU 41 342 342 LEU LEU X . n |
| A 1 42 GLU 42 343 343 GLU GLU X . n |
| A 1 43 ALA 43 344 344 ALA ALA X . n |
| A 1 44 TYR 44 345 345 TYR TYR X . n |
| A 1 45 ASN 45 346 346 ASN ASN X . n |
| A 1 46 PRO 46 347 347 PRO PRO X . n |
| A 1 47 SER 47 348 348 SER SER X . n |
| A 1 48 ASP 48 349 349 ASP ASP X . n |
| A 1 49 GLY 49 350 350 GLY GLY X . n |
| A 1 50 THR 50 351 351 THR THR X . n |
| A 1 51 TRP 51 352 352 TRP TRP X . n |
| A 1 52 LEU 52 353 353 LEU LEU X . n |
| A 1 53 ARG 53 354 354 ARG ARG X . n |
| A 1 54 LEU 54 355 355 LEU LEU X . n |
| A 1 55 ALA 55 356 356 ALA ALA X . n |
| A 1 56 ASP 56 357 357 ASP ASP X . n |
| A 1 57 LEU 57 358 358 LEU LEU X . n |
| A 1 58 GLN 58 359 359 GLN GLN X . n |
| A 1 59 VAL 59 360 360 VAL VAL X . n |
| A 1 60 PRO 60 361 361 PRO PRO X . n |
| A 1 61 ARG 61 362 362 ARG ARG X . n |
| A 1 62 SER 62 363 363 SER SER X . n |
| A 1 63 GLY 63 364 364 GLY GLY X . n |
| A 1 64 LEU 64 365 365 LEU LEU X . n |
| A 1 65 ALA 65 366 366 ALA ALA X . n |
| A 1 66 GLY 66 367 367 GLY GLY X . n |
| A 1 67 CYS 67 368 368 CYS CYS X . n |
| A 1 68 VAL 68 369 369 VAL VAL X . n |
| A 1 69 VAL 69 370 370 VAL VAL X . n |
| A 1 70 GLY 70 371 371 GLY GLY X . n |
| A 1 71 GLY 71 372 372 GLY GLY X . n |
| A 1 72 LEU 72 373 373 LEU LEU X . n |
| A 1 73 LEU 73 374 374 LEU LEU X . n |
| A 1 74 TYR 74 375 375 TYR TYR X . n |
| A 1 75 ALA 75 376 376 ALA ALA X . n |
| A 1 76 VAL 76 377 377 VAL VAL X . n |
| A 1 77 GLY 77 378 378 GLY GLY X . n |
| A 1 78 GLY 78 379 379 GLY GLY X . n |
| A 1 79 ARG 79 380 380 ARG ARG X . n |
| A 1 80 ASN 80 381 381 ASN ASN X . n |
| A 1 81 ASN 81 382 382 ASN ASN X . n |
| A 1 82 SER 82 383 383 SER SER X . n |
| A 1 83 PRO 83 384 384 PRO PRO X . n |
| A 1 84 ASP 84 385 385 ASP ASP X . n |
| A 1 85 GLY 85 386 386 GLY GLY X . n |
| A 1 86 ASN 86 387 387 ASN ASN X . n |
| A 1 87 THR 87 388 388 THR THR X . n |
| A 1 88 ASP 88 389 389 ASP ASP X . n |
| A 1 89 SER 89 390 390 SER SER X . n |
| A 1 90 SER 90 391 391 SER SER X . n |
| A 1 91 ALA 91 392 392 ALA ALA X . n |
| A 1 92 LEU 92 393 393 LEU LEU X . n |
| A 1 93 ASP 93 394 394 ASP ASP X . n |
| A 1 94 CYS 94 395 395 CYS CYS X . n |
| A 1 95 TYR 95 396 396 TYR TYR X . n |
| A 1 96 ASN 96 397 397 ASN ASN X . n |
| A 1 97 PRO 97 398 398 PRO PRO X . n |
| A 1 98 MET 98 399 399 MET MET X . n |
| A 1 99 THR 99 400 400 THR THR X . n |
| A 1 100 ASN 100 401 401 ASN ASN X . n |
| A 1 101 GLN 101 402 402 GLN GLN X . n |
| A 1 102 TRP 102 403 403 TRP TRP X . n |
| A 1 103 SER 103 404 404 SER SER X . n |
| A 1 104 PRO 104 405 405 PRO PRO X . n |
| A 1 105 CYS 105 406 406 CYS CYS X . n |
| A 1 106 ALA 106 407 407 ALA ALA X . n |
| A 1 107 PRO 107 408 408 PRO PRO X . n |
| A 1 108 MET 108 409 409 MET MET X . n |
| A 1 109 SER 109 410 410 SER SER X . n |
| A 1 110 VAL 110 411 411 VAL VAL X . n |
| A 1 111 PRO 111 412 412 PRO PRO X . n |
| A 1 112 ARG 112 413 413 ARG ARG X . n |
| A 1 113 ASN 113 414 414 ASN ASN X . n |
| A 1 114 ARG 114 415 415 ARG ARG X . n |
| A 1 115 ILE 115 416 416 ILE ILE X . n |
| A 1 116 GLY 116 417 417 GLY GLY X . n |
| A 1 117 VAL 117 418 418 VAL VAL X . n |
| A 1 118 GLY 118 419 419 GLY GLY X . n |
| A 1 119 VAL 119 420 420 VAL VAL X . n |
| A 1 120 ILE 120 421 421 ILE ILE X . n |
| A 1 121 ASP 121 422 422 ASP ASP X . n |
| A 1 122 GLY 122 423 423 GLY GLY X . n |
| A 1 123 HIS 123 424 424 HIS HIS X . n |
| A 1 124 ILE 124 425 425 ILE ILE X . n |
| A 1 125 TYR 125 426 426 TYR TYR X . n |
| A 1 126 ALA 126 427 427 ALA ALA X . n |
| A 1 127 VAL 127 428 428 VAL VAL X . n |
| A 1 128 GLY 128 429 429 GLY GLY X . n |
| A 1 129 GLY 129 430 430 GLY GLY X . n |
| A 1 130 SER 130 431 431 SER SER X . n |
| A 1 131 HIS 131 432 432 HIS HIS X . n |
| A 1 132 GLY 132 433 433 GLY GLY X . n |
| A 1 133 CYS 133 434 434 CYS CYS X . n |
| A 1 134 ILE 134 435 435 ILE ILE X . n |
| A 1 135 HIS 135 436 436 HIS HIS X . n |
| A 1 136 HIS 136 437 437 HIS HIS X . n |
| A 1 137 ASN 137 438 438 ASN ASN X . n |
| A 1 138 SER 138 439 439 SER SER X . n |
| A 1 139 VAL 139 440 440 VAL VAL X . n |
| A 1 140 GLU 140 441 441 GLU GLU X . n |
| A 1 141 ARG 141 442 442 ARG ARG X . n |
| A 1 142 TYR 142 443 443 TYR TYR X . n |
| A 1 143 GLU 143 444 444 GLU GLU X . n |
| A 1 144 PRO 144 445 445 PRO PRO X . n |
| A 1 145 GLU 145 446 446 GLU GLU X . n |
| A 1 146 ARG 146 447 447 ARG ARG X . n |
| A 1 147 ASP 147 448 448 ASP ASP X . n |
| A 1 148 GLU 148 449 449 GLU GLU X . n |
| A 1 149 TRP 149 450 450 TRP TRP X . n |
| A 1 150 HIS 150 451 451 HIS HIS X . n |
| A 1 151 LEU 151 452 452 LEU LEU X . n |
| A 1 152 VAL 152 453 453 VAL VAL X . n |
| A 1 153 ALA 153 454 454 ALA ALA X . n |
| A 1 154 PRO 154 455 455 PRO PRO X . n |
| A 1 155 MET 155 456 456 MET MET X . n |
| A 1 156 LEU 156 457 457 LEU LEU X . n |
| A 1 157 THR 157 458 458 THR THR X . n |
| A 1 158 ARG 158 459 459 ARG ARG X . n |
| A 1 159 ARG 159 460 460 ARG ARG X . n |
| A 1 160 ILE 160 461 461 ILE ILE X . n |
| A 1 161 GLY 161 462 462 GLY GLY X . n |
| A 1 162 VAL 162 463 463 VAL VAL X . n |
| A 1 163 GLY 163 464 464 GLY GLY X . n |
| A 1 164 VAL 164 465 465 VAL VAL X . n |
| A 1 165 ALA 165 466 466 ALA ALA X . n |
| A 1 166 VAL 166 467 467 VAL VAL X . n |
| A 1 167 LEU 167 468 468 LEU LEU X . n |
| A 1 168 ASN 168 469 469 ASN ASN X . n |
| A 1 169 ARG 169 470 470 ARG ARG X . n |
| A 1 170 LEU 170 471 471 LEU LEU X . n |
| A 1 171 LEU 171 472 472 LEU LEU X . n |
| A 1 172 TYR 172 473 473 TYR TYR X . n |
| A 1 173 ALA 173 474 474 ALA ALA X . n |
| A 1 174 VAL 174 475 475 VAL VAL X . n |
| A 1 175 GLY 175 476 476 GLY GLY X . n |
| A 1 176 GLY 176 477 477 GLY GLY X . n |
| A 1 177 PHE 177 478 478 PHE PHE X . n |
| A 1 178 ASP 178 479 479 ASP ASP X . n |
| A 1 179 GLY 179 480 480 GLY GLY X . n |
| A 1 180 THR 180 481 481 THR THR X . n |
| A 1 181 ASN 181 482 482 ASN ASN X . n |
| A 1 182 ARG 182 483 483 ARG ARG X . n |
| A 1 183 LEU 183 484 484 LEU LEU X . n |
| A 1 184 ASN 184 485 485 ASN ASN X . n |
| A 1 185 SER 185 486 486 SER SER X . n |
| A 1 186 ALA 186 487 487 ALA ALA X . n |
| A 1 187 GLU 187 488 488 GLU GLU X . n |
| A 1 188 CYS 188 489 489 CYS CYS X . n |
| A 1 189 TYR 189 490 490 TYR TYR X . n |
| A 1 190 TYR 190 491 491 TYR TYR X . n |
| A 1 191 PRO 191 492 492 PRO PRO X . n |
| A 1 192 GLU 192 493 493 GLU GLU X . n |
| A 1 193 ARG 193 494 494 ARG ARG X . n |
| A 1 194 ASN 194 495 495 ASN ASN X . n |
| A 1 195 GLU 195 496 496 GLU GLU X . n |
| A 1 196 TRP 196 497 497 TRP TRP X . n |
| A 1 197 ARG 197 498 498 ARG ARG X . n |
| A 1 198 MET 198 499 499 MET MET X . n |
| A 1 199 ILE 199 500 500 ILE ILE X . n |
| A 1 200 THR 200 501 501 THR THR X . n |
| A 1 201 ALA 201 502 502 ALA ALA X . n |
| A 1 202 MET 202 503 503 MET MET X . n |
| A 1 203 ASN 203 504 504 ASN ASN X . n |
| A 1 204 THR 204 505 505 THR THR X . n |
| A 1 205 ILE 205 506 506 ILE ILE X . n |
| A 1 206 ARG 206 507 507 ARG ARG X . n |
| A 1 207 SER 207 508 508 SER SER X . n |
| A 1 208 GLY 208 509 509 GLY GLY X . n |
| A 1 209 ALA 209 510 510 ALA ALA X . n |
| A 1 210 GLY 210 511 511 GLY GLY X . n |
| A 1 211 VAL 211 512 512 VAL VAL X . n |
| A 1 212 CYS 212 513 513 CYS CYS X . n |
| A 1 213 VAL 213 514 514 VAL VAL X . n |
| A 1 214 LEU 214 515 515 LEU LEU X . n |
| A 1 215 HIS 215 516 516 HIS HIS X . n |
| A 1 216 ASN 216 517 517 ASN ASN X . n |
| A 1 217 CYS 217 518 518 CYS CYS X . n |
| A 1 218 ILE 218 519 519 ILE ILE X . n |
| A 1 219 TYR 219 520 520 TYR TYR X . n |
| A 1 220 ALA 220 521 521 ALA ALA X . n |
| A 1 221 ALA 221 522 522 ALA ALA X . n |
| A 1 222 GLY 222 523 523 GLY GLY X . n |
| A 1 223 GLY 223 524 524 GLY GLY X . n |
| A 1 224 TYR 224 525 525 TYR TYR X . n |
| A 1 225 ASP 225 526 526 ASP ASP X . n |
| A 1 226 GLY 226 527 527 GLY GLY X . n |
| A 1 227 GLN 227 528 528 GLN GLN X . n |
| A 1 228 ASP 228 529 529 ASP ASP X . n |
| A 1 229 GLN 229 530 530 GLN GLN X . n |
| A 1 230 LEU 230 531 531 LEU LEU X . n |
| A 1 231 ASN 231 532 532 ASN ASN X . n |
| A 1 232 SER 232 533 533 SER SER X . n |
| A 1 233 VAL 233 534 534 VAL VAL X . n |
| A 1 234 GLU 234 535 535 GLU GLU X . n |
| A 1 235 ARG 235 536 536 ARG ARG X . n |
| A 1 236 TYR 236 537 537 TYR TYR X . n |
| A 1 237 ASP 237 538 538 ASP ASP X . n |
| A 1 238 VAL 238 539 539 VAL VAL X . n |
| A 1 239 GLU 239 540 540 GLU GLU X . n |
| A 1 240 THR 240 541 541 THR THR X . n |
| A 1 241 GLU 241 542 542 GLU GLU X . n |
| A 1 242 THR 242 543 543 THR THR X . n |
| A 1 243 TRP 243 544 544 TRP TRP X . n |
| A 1 244 THR 244 545 545 THR THR X . n |
| A 1 245 PHE 245 546 546 PHE PHE X . n |
| A 1 246 VAL 246 547 547 VAL VAL X . n |
| A 1 247 ALA 247 548 548 ALA ALA X . n |
| A 1 248 PRO 248 549 549 PRO PRO X . n |
| A 1 249 MET 249 550 550 MET MET X . n |
| A 1 250 LYS 250 551 551 LYS LYS X . n |
| A 1 251 HIS 251 552 552 HIS HIS X . n |
| A 1 252 ARG 252 553 553 ARG ARG X . n |
| A 1 253 ARG 253 554 554 ARG ARG X . n |
| A 1 254 SER 254 555 555 SER SER X . n |
| A 1 255 ALA 255 556 556 ALA ALA X . n |
| A 1 256 LEU 256 557 557 LEU LEU X . n |
| A 1 257 GLY 257 558 558 GLY GLY X . n |
| A 1 258 ILE 258 559 559 ILE ILE X . n |
| A 1 259 THR 259 560 560 THR THR X . n |
| A 1 260 VAL 260 561 561 VAL VAL X . n |
| A 1 261 HIS 261 562 562 HIS HIS X . n |
| A 1 262 GLN 262 563 563 GLN GLN X . n |
| A 1 263 GLY 263 564 564 GLY GLY X . n |
| A 1 264 ARG 264 565 565 ARG ARG X . n |
| A 1 265 ILE 265 566 566 ILE ILE X . n |
| A 1 266 TYR 266 567 567 TYR TYR X . n |
| A 1 267 VAL 267 568 568 VAL VAL X . n |
| A 1 268 LEU 268 569 569 LEU LEU X . n |
| A 1 269 GLY 269 570 570 GLY GLY X . n |
| A 1 270 GLY 270 571 571 GLY GLY X . n |
| A 1 271 TYR 271 572 572 TYR TYR X . n |
| A 1 272 ASP 272 573 573 ASP ASP X . n |
| A 1 273 GLY 273 574 574 GLY GLY X . n |
| A 1 274 HIS 274 575 575 HIS HIS X . n |
| A 1 275 THR 275 576 576 THR THR X . n |
| A 1 276 PHE 276 577 577 PHE PHE X . n |
| A 1 277 LEU 277 578 578 LEU LEU X . n |
| A 1 278 ASP 278 579 579 ASP ASP X . n |
| A 1 279 SER 279 580 580 SER SER X . n |
| A 1 280 VAL 280 581 581 VAL VAL X . n |
| A 1 281 GLU 281 582 582 GLU GLU X . n |
| A 1 282 CYS 282 583 583 CYS CYS X . n |
| A 1 283 TYR 283 584 584 TYR TYR X . n |
| A 1 284 ASP 284 585 585 ASP ASP X . n |
| A 1 285 PRO 285 586 586 PRO PRO X . n |
| A 1 286 ASP 286 587 587 ASP ASP X . n |
| A 1 287 THR 287 588 588 THR THR X . n |
| A 1 288 ASP 288 589 589 ASP ASP X . n |
| A 1 289 THR 289 590 590 THR THR X . n |
| A 1 290 TRP 290 591 591 TRP TRP X . n |
| A 1 291 SER 291 592 592 SER SER X . n |
| A 1 292 GLU 292 593 593 GLU GLU X . n |
| A 1 293 VAL 293 594 594 VAL VAL X . n |
| A 1 294 THR 294 595 595 THR THR X . n |
| A 1 295 ARG 295 596 596 ARG ARG X . n |
| A 1 296 MET 296 597 597 MET MET X . n |
| A 1 297 THR 297 598 598 THR THR X . n |
| A 1 298 SER 298 599 599 SER SER X . n |
| A 1 299 GLY 299 600 600 GLY GLY X . n |
| A 1 300 ARG 300 601 601 ARG ARG X . n |
| A 1 301 SER 301 602 602 SER SER X . n |
| A 1 302 GLY 302 603 603 GLY GLY X . n |
| A 1 303 VAL 303 604 604 VAL VAL X . n |
| A 1 304 GLY 304 605 605 GLY GLY X . n |
| A 1 305 VAL 305 606 606 VAL VAL X . n |
| A 1 306 ALA 306 607 607 ALA ALA X . n |
| A 1 307 VAL 307 608 608 VAL VAL X . n |
| A 1 308 THR 308 609 609 THR THR X . n |
| B 2 1 ALA 1 69 69 ALA ALA P . n |
| B 2 2 PHE 2 70 70 PHE PHE P . n |
| B 2 3 PHE 3 71 71 PHE PHE P . n |
| B 2 4 ALA 4 72 72 ALA ALA P . n |
| B 2 5 GLN 5 73 73 GLN GLN P . n |
| B 2 6 LEU 6 74 74 LEU LEU P . n |
| B 2 7 GLN 7 75 75 GLN GLN P . n |
| B 2 8 LEU 8 76 76 LEU LEU P . n |
| B 2 9 ASP 9 77 77 ASP ASP P . n |
| B 2 10 GLU 10 78 78 GLU GLU P . n |
| B 2 11 GLU 11 79 79 GLU GLU P . n |
| B 2 12 THR 12 80 80 THR THR P . n |
| B 2 13 GLY 13 81 81 GLY GLY P . n |
| B 2 14 GLU 14 82 82 GLU GLU P . n |
| B 2 15 PHE 15 83 83 PHE PHE P . n |
| B 2 16 LEU 16 84 84 LEU LEU P . n |
| |
| loop_ |
| _pdbx_nonpoly_scheme.asym_id |
| _pdbx_nonpoly_scheme.entity_id |
| _pdbx_nonpoly_scheme.mon_id |
| _pdbx_nonpoly_scheme.ndb_seq_num |
| _pdbx_nonpoly_scheme.pdb_seq_num |
| _pdbx_nonpoly_scheme.auth_seq_num |
| _pdbx_nonpoly_scheme.pdb_mon_id |
| _pdbx_nonpoly_scheme.auth_mon_id |
| _pdbx_nonpoly_scheme.pdb_strand_id |
| _pdbx_nonpoly_scheme.pdb_ins_code |
| C 3 HOH 1 610 1 HOH HOH X . |
| C 3 HOH 2 611 2 HOH HOH X . |
| C 3 HOH 3 612 3 HOH HOH X . |
| C 3 HOH 4 613 5 HOH HOH X . |
| C 3 HOH 5 614 6 HOH HOH X . |
| C 3 HOH 6 615 7 HOH HOH X . |
| C 3 HOH 7 616 8 HOH HOH X . |
| C 3 HOH 8 617 9 HOH HOH X . |
| C 3 HOH 9 618 10 HOH HOH X . |
| C 3 HOH 10 619 11 HOH HOH X . |
| C 3 HOH 11 620 12 HOH HOH X . |
| C 3 HOH 12 621 13 HOH HOH X . |
| C 3 HOH 13 622 14 HOH HOH X . |
| C 3 HOH 14 623 15 HOH HOH X . |
| C 3 HOH 15 624 16 HOH HOH X . |
| C 3 HOH 16 625 17 HOH HOH X . |
| C 3 HOH 17 626 18 HOH HOH X . |
| C 3 HOH 18 627 19 HOH HOH X . |
| C 3 HOH 19 628 20 HOH HOH X . |
| C 3 HOH 20 629 21 HOH HOH X . |
| C 3 HOH 21 630 22 HOH HOH X . |
| C 3 HOH 22 631 23 HOH HOH X . |
| C 3 HOH 23 632 25 HOH HOH X . |
| C 3 HOH 24 633 26 HOH HOH X . |
| C 3 HOH 25 634 27 HOH HOH X . |
| C 3 HOH 26 635 28 HOH HOH X . |
| C 3 HOH 27 636 29 HOH HOH X . |
| C 3 HOH 28 637 30 HOH HOH X . |
| C 3 HOH 29 638 31 HOH HOH X . |
| C 3 HOH 30 639 32 HOH HOH X . |
| C 3 HOH 31 640 33 HOH HOH X . |
| C 3 HOH 32 641 34 HOH HOH X . |
| C 3 HOH 33 642 35 HOH HOH X . |
| C 3 HOH 34 643 36 HOH HOH X . |
| C 3 HOH 35 644 37 HOH HOH X . |
| C 3 HOH 36 645 38 HOH HOH X . |
| C 3 HOH 37 646 39 HOH HOH X . |
| C 3 HOH 38 647 41 HOH HOH X . |
| C 3 HOH 39 648 42 HOH HOH X . |
| C 3 HOH 40 649 43 HOH HOH X . |
| C 3 HOH 41 650 44 HOH HOH X . |
| C 3 HOH 42 651 46 HOH HOH X . |
| C 3 HOH 43 652 47 HOH HOH X . |
| C 3 HOH 44 653 48 HOH HOH X . |
| C 3 HOH 45 654 49 HOH HOH X . |
| C 3 HOH 46 655 50 HOH HOH X . |
| C 3 HOH 47 656 51 HOH HOH X . |
| C 3 HOH 48 657 52 HOH HOH X . |
| C 3 HOH 49 658 53 HOH HOH X . |
| C 3 HOH 50 659 54 HOH HOH X . |
| C 3 HOH 51 660 55 HOH HOH X . |
| C 3 HOH 52 661 56 HOH HOH X . |
| C 3 HOH 53 662 57 HOH HOH X . |
| C 3 HOH 54 663 58 HOH HOH X . |
| C 3 HOH 55 664 59 HOH HOH X . |
| C 3 HOH 56 665 60 HOH HOH X . |
| C 3 HOH 57 666 61 HOH HOH X . |
| C 3 HOH 58 667 63 HOH HOH X . |
| C 3 HOH 59 668 64 HOH HOH X . |
| C 3 HOH 60 669 65 HOH HOH X . |
| C 3 HOH 61 670 66 HOH HOH X . |
| C 3 HOH 62 671 68 HOH HOH X . |
| C 3 HOH 63 672 69 HOH HOH X . |
| C 3 HOH 64 673 70 HOH HOH X . |
| C 3 HOH 65 674 71 HOH HOH X . |
| C 3 HOH 66 675 72 HOH HOH X . |
| C 3 HOH 67 676 73 HOH HOH X . |
| C 3 HOH 68 677 74 HOH HOH X . |
| C 3 HOH 69 678 75 HOH HOH X . |
| C 3 HOH 70 679 76 HOH HOH X . |
| C 3 HOH 71 680 77 HOH HOH X . |
| C 3 HOH 72 681 78 HOH HOH X . |
| C 3 HOH 73 682 79 HOH HOH X . |
| C 3 HOH 74 683 81 HOH HOH X . |
| C 3 HOH 75 684 82 HOH HOH X . |
| C 3 HOH 76 685 83 HOH HOH X . |
| C 3 HOH 77 686 84 HOH HOH X . |
| C 3 HOH 78 687 85 HOH HOH X . |
| C 3 HOH 79 688 86 HOH HOH X . |
| C 3 HOH 80 689 87 HOH HOH X . |
| C 3 HOH 81 690 88 HOH HOH X . |
| C 3 HOH 82 691 89 HOH HOH X . |
| C 3 HOH 83 692 90 HOH HOH X . |
| C 3 HOH 84 693 91 HOH HOH X . |
| C 3 HOH 85 694 92 HOH HOH X . |
| C 3 HOH 86 695 93 HOH HOH X . |
| C 3 HOH 87 696 94 HOH HOH X . |
| C 3 HOH 88 697 95 HOH HOH X . |
| C 3 HOH 89 698 96 HOH HOH X . |
| C 3 HOH 90 699 97 HOH HOH X . |
| C 3 HOH 91 700 99 HOH HOH X . |
| C 3 HOH 92 701 100 HOH HOH X . |
| C 3 HOH 93 702 101 HOH HOH X . |
| C 3 HOH 94 703 102 HOH HOH X . |
| C 3 HOH 95 704 103 HOH HOH X . |
| C 3 HOH 96 705 104 HOH HOH X . |
| C 3 HOH 97 706 105 HOH HOH X . |
| C 3 HOH 98 707 106 HOH HOH X . |
| C 3 HOH 99 708 107 HOH HOH X . |
| C 3 HOH 100 709 108 HOH HOH X . |
| C 3 HOH 101 710 109 HOH HOH X . |
| C 3 HOH 102 711 111 HOH HOH X . |
| C 3 HOH 103 712 112 HOH HOH X . |
| C 3 HOH 104 713 113 HOH HOH X . |
| C 3 HOH 105 714 114 HOH HOH X . |
| C 3 HOH 106 715 115 HOH HOH X . |
| C 3 HOH 107 716 116 HOH HOH X . |
| C 3 HOH 108 717 117 HOH HOH X . |
| C 3 HOH 109 718 118 HOH HOH X . |
| C 3 HOH 110 719 119 HOH HOH X . |
| C 3 HOH 111 720 120 HOH HOH X . |
| C 3 HOH 112 721 121 HOH HOH X . |
| C 3 HOH 113 722 122 HOH HOH X . |
| C 3 HOH 114 723 123 HOH HOH X . |
| C 3 HOH 115 724 124 HOH HOH X . |
| C 3 HOH 116 725 126 HOH HOH X . |
| C 3 HOH 117 726 127 HOH HOH X . |
| C 3 HOH 118 727 128 HOH HOH X . |
| C 3 HOH 119 728 129 HOH HOH X . |
| C 3 HOH 120 729 130 HOH HOH X . |
| C 3 HOH 121 730 131 HOH HOH X . |
| C 3 HOH 122 731 132 HOH HOH X . |
| C 3 HOH 123 732 133 HOH HOH X . |
| C 3 HOH 124 733 134 HOH HOH X . |
| C 3 HOH 125 734 135 HOH HOH X . |
| C 3 HOH 126 735 136 HOH HOH X . |
| C 3 HOH 127 736 137 HOH HOH X . |
| C 3 HOH 128 737 138 HOH HOH X . |
| C 3 HOH 129 738 139 HOH HOH X . |
| C 3 HOH 130 739 140 HOH HOH X . |
| C 3 HOH 131 740 141 HOH HOH X . |
| C 3 HOH 132 741 142 HOH HOH X . |
| C 3 HOH 133 742 143 HOH HOH X . |
| C 3 HOH 134 743 144 HOH HOH X . |
| C 3 HOH 135 744 145 HOH HOH X . |
| C 3 HOH 136 745 146 HOH HOH X . |
| C 3 HOH 137 746 147 HOH HOH X . |
| C 3 HOH 138 747 148 HOH HOH X . |
| C 3 HOH 139 748 149 HOH HOH X . |
| C 3 HOH 140 749 150 HOH HOH X . |
| C 3 HOH 141 750 151 HOH HOH X . |
| C 3 HOH 142 751 152 HOH HOH X . |
| C 3 HOH 143 752 153 HOH HOH X . |
| C 3 HOH 144 753 154 HOH HOH X . |
| C 3 HOH 145 754 155 HOH HOH X . |
| C 3 HOH 146 755 156 HOH HOH X . |
| C 3 HOH 147 756 157 HOH HOH X . |
| C 3 HOH 148 757 158 HOH HOH X . |
| C 3 HOH 149 758 159 HOH HOH X . |
| C 3 HOH 150 759 160 HOH HOH X . |
| C 3 HOH 151 760 161 HOH HOH X . |
| C 3 HOH 152 761 162 HOH HOH X . |
| C 3 HOH 153 762 163 HOH HOH X . |
| C 3 HOH 154 763 164 HOH HOH X . |
| C 3 HOH 155 764 165 HOH HOH X . |
| C 3 HOH 156 765 166 HOH HOH X . |
| C 3 HOH 157 766 167 HOH HOH X . |
| C 3 HOH 158 767 168 HOH HOH X . |
| C 3 HOH 159 768 169 HOH HOH X . |
| C 3 HOH 160 769 170 HOH HOH X . |
| C 3 HOH 161 770 171 HOH HOH X . |
| C 3 HOH 162 771 172 HOH HOH X . |
| C 3 HOH 163 772 173 HOH HOH X . |
| C 3 HOH 164 773 174 HOH HOH X . |
| C 3 HOH 165 774 175 HOH HOH X . |
| C 3 HOH 166 775 177 HOH HOH X . |
| C 3 HOH 167 776 178 HOH HOH X . |
| C 3 HOH 168 777 179 HOH HOH X . |
| C 3 HOH 169 778 180 HOH HOH X . |
| C 3 HOH 170 779 181 HOH HOH X . |
| C 3 HOH 171 780 182 HOH HOH X . |
| C 3 HOH 172 781 183 HOH HOH X . |
| C 3 HOH 173 782 184 HOH HOH X . |
| C 3 HOH 174 783 185 HOH HOH X . |
| C 3 HOH 175 784 186 HOH HOH X . |
| C 3 HOH 176 785 187 HOH HOH X . |
| C 3 HOH 177 786 188 HOH HOH X . |
| C 3 HOH 178 787 189 HOH HOH X . |
| C 3 HOH 179 788 190 HOH HOH X . |
| C 3 HOH 180 789 191 HOH HOH X . |
| C 3 HOH 181 790 192 HOH HOH X . |
| C 3 HOH 182 791 193 HOH HOH X . |
| C 3 HOH 183 792 194 HOH HOH X . |
| C 3 HOH 184 793 195 HOH HOH X . |
| C 3 HOH 185 794 196 HOH HOH X . |
| C 3 HOH 186 795 197 HOH HOH X . |
| C 3 HOH 187 796 198 HOH HOH X . |
| C 3 HOH 188 797 199 HOH HOH X . |
| C 3 HOH 189 798 200 HOH HOH X . |
| C 3 HOH 190 799 201 HOH HOH X . |
| C 3 HOH 191 800 202 HOH HOH X . |
| C 3 HOH 192 801 203 HOH HOH X . |
| C 3 HOH 193 802 204 HOH HOH X . |
| C 3 HOH 194 803 205 HOH HOH X . |
| C 3 HOH 195 804 206 HOH HOH X . |
| C 3 HOH 196 805 207 HOH HOH X . |
| C 3 HOH 197 806 208 HOH HOH X . |
| C 3 HOH 198 807 209 HOH HOH X . |
| C 3 HOH 199 808 210 HOH HOH X . |
| C 3 HOH 200 809 211 HOH HOH X . |
| C 3 HOH 201 810 212 HOH HOH X . |
| C 3 HOH 202 811 213 HOH HOH X . |
| C 3 HOH 203 812 214 HOH HOH X . |
| C 3 HOH 204 813 215 HOH HOH X . |
| C 3 HOH 205 814 216 HOH HOH X . |
| C 3 HOH 206 815 217 HOH HOH X . |
| C 3 HOH 207 816 218 HOH HOH X . |
| C 3 HOH 208 817 219 HOH HOH X . |
| C 3 HOH 209 818 221 HOH HOH X . |
| C 3 HOH 210 819 222 HOH HOH X . |
| C 3 HOH 211 820 223 HOH HOH X . |
| C 3 HOH 212 821 224 HOH HOH X . |
| C 3 HOH 213 822 225 HOH HOH X . |
| C 3 HOH 214 823 226 HOH HOH X . |
| C 3 HOH 215 824 227 HOH HOH X . |
| C 3 HOH 216 825 228 HOH HOH X . |
| C 3 HOH 217 826 229 HOH HOH X . |
| C 3 HOH 218 827 230 HOH HOH X . |
| C 3 HOH 219 828 231 HOH HOH X . |
| C 3 HOH 220 829 232 HOH HOH X . |
| C 3 HOH 221 830 233 HOH HOH X . |
| C 3 HOH 222 831 234 HOH HOH X . |
| C 3 HOH 223 832 235 HOH HOH X . |
| C 3 HOH 224 833 236 HOH HOH X . |
| C 3 HOH 225 834 237 HOH HOH X . |
| C 3 HOH 226 835 238 HOH HOH X . |
| C 3 HOH 227 836 239 HOH HOH X . |
| C 3 HOH 228 837 240 HOH HOH X . |
| C 3 HOH 229 838 241 HOH HOH X . |
| C 3 HOH 230 839 242 HOH HOH X . |
| C 3 HOH 231 840 243 HOH HOH X . |
| C 3 HOH 232 841 244 HOH HOH X . |
| C 3 HOH 233 842 245 HOH HOH X . |
| C 3 HOH 234 843 247 HOH HOH X . |
| C 3 HOH 235 844 248 HOH HOH X . |
| C 3 HOH 236 845 249 HOH HOH X . |
| C 3 HOH 237 846 250 HOH HOH X . |
| C 3 HOH 238 847 251 HOH HOH X . |
| C 3 HOH 239 848 252 HOH HOH X . |
| C 3 HOH 240 849 253 HOH HOH X . |
| C 3 HOH 241 850 254 HOH HOH X . |
| C 3 HOH 242 851 255 HOH HOH X . |
| C 3 HOH 243 852 256 HOH HOH X . |
| C 3 HOH 244 853 257 HOH HOH X . |
| C 3 HOH 245 854 260 HOH HOH X . |
| C 3 HOH 246 855 261 HOH HOH X . |
| C 3 HOH 247 856 262 HOH HOH X . |
| C 3 HOH 248 857 263 HOH HOH X . |
| C 3 HOH 249 858 264 HOH HOH X . |
| C 3 HOH 250 859 265 HOH HOH X . |
| C 3 HOH 251 860 267 HOH HOH X . |
| C 3 HOH 252 861 268 HOH HOH X . |
| C 3 HOH 253 862 269 HOH HOH X . |
| C 3 HOH 254 863 270 HOH HOH X . |
| C 3 HOH 255 864 271 HOH HOH X . |
| C 3 HOH 256 865 272 HOH HOH X . |
| C 3 HOH 257 866 273 HOH HOH X . |
| C 3 HOH 258 867 274 HOH HOH X . |
| C 3 HOH 259 868 275 HOH HOH X . |
| C 3 HOH 260 869 276 HOH HOH X . |
| C 3 HOH 261 870 277 HOH HOH X . |
| C 3 HOH 262 871 278 HOH HOH X . |
| C 3 HOH 263 872 279 HOH HOH X . |
| C 3 HOH 264 873 280 HOH HOH X . |
| C 3 HOH 265 874 281 HOH HOH X . |
| C 3 HOH 266 875 282 HOH HOH X . |
| C 3 HOH 267 876 283 HOH HOH X . |
| C 3 HOH 268 877 284 HOH HOH X . |
| C 3 HOH 269 878 287 HOH HOH X . |
| C 3 HOH 270 879 288 HOH HOH X . |
| C 3 HOH 271 880 289 HOH HOH X . |
| C 3 HOH 272 881 290 HOH HOH X . |
| C 3 HOH 273 882 291 HOH HOH X . |
| C 3 HOH 274 883 292 HOH HOH X . |
| C 3 HOH 275 884 293 HOH HOH X . |
| C 3 HOH 276 885 294 HOH HOH X . |
| C 3 HOH 277 886 295 HOH HOH X . |
| C 3 HOH 278 887 296 HOH HOH X . |
| C 3 HOH 279 888 297 HOH HOH X . |
| C 3 HOH 280 889 298 HOH HOH X . |
| C 3 HOH 281 890 299 HOH HOH X . |
| C 3 HOH 282 891 300 HOH HOH X . |
| C 3 HOH 283 892 301 HOH HOH X . |
| C 3 HOH 284 893 302 HOH HOH X . |
| C 3 HOH 285 894 303 HOH HOH X . |
| C 3 HOH 286 895 304 HOH HOH X . |
| C 3 HOH 287 896 305 HOH HOH X . |
| C 3 HOH 288 897 306 HOH HOH X . |
| C 3 HOH 289 898 307 HOH HOH X . |
| C 3 HOH 290 899 308 HOH HOH X . |
| C 3 HOH 291 900 309 HOH HOH X . |
| C 3 HOH 292 901 311 HOH HOH X . |
| C 3 HOH 293 902 312 HOH HOH X . |
| C 3 HOH 294 903 313 HOH HOH X . |
| C 3 HOH 295 904 314 HOH HOH X . |
| C 3 HOH 296 905 315 HOH HOH X . |
| C 3 HOH 297 906 316 HOH HOH X . |
| C 3 HOH 298 907 317 HOH HOH X . |
| C 3 HOH 299 908 318 HOH HOH X . |
| C 3 HOH 300 909 319 HOH HOH X . |
| C 3 HOH 301 910 320 HOH HOH X . |
| C 3 HOH 302 911 321 HOH HOH X . |
| C 3 HOH 303 912 322 HOH HOH X . |
| C 3 HOH 304 913 323 HOH HOH X . |
| C 3 HOH 305 914 325 HOH HOH X . |
| C 3 HOH 306 915 326 HOH HOH X . |
| C 3 HOH 307 916 327 HOH HOH X . |
| C 3 HOH 308 917 328 HOH HOH X . |
| C 3 HOH 309 918 329 HOH HOH X . |
| C 3 HOH 310 919 330 HOH HOH X . |
| C 3 HOH 311 920 331 HOH HOH X . |
| C 3 HOH 312 921 332 HOH HOH X . |
| C 3 HOH 313 922 333 HOH HOH X . |
| D 3 HOH 1 85 4 HOH HOH P . |
| D 3 HOH 2 86 24 HOH HOH P . |
| D 3 HOH 3 87 40 HOH HOH P . |
| D 3 HOH 4 88 45 HOH HOH P . |
| D 3 HOH 5 89 62 HOH HOH P . |
| D 3 HOH 6 90 67 HOH HOH P . |
| D 3 HOH 7 91 80 HOH HOH P . |
| D 3 HOH 8 92 98 HOH HOH P . |
| D 3 HOH 9 93 110 HOH HOH P . |
| D 3 HOH 10 94 125 HOH HOH P . |
| D 3 HOH 11 95 176 HOH HOH P . |
| D 3 HOH 12 96 220 HOH HOH P . |
| D 3 HOH 13 97 246 HOH HOH P . |
| D 3 HOH 14 98 258 HOH HOH P . |
| D 3 HOH 15 99 259 HOH HOH P . |
| D 3 HOH 16 100 266 HOH HOH P . |
| D 3 HOH 17 101 285 HOH HOH P . |
| D 3 HOH 18 102 286 HOH HOH P . |
| D 3 HOH 19 103 310 HOH HOH P . |
| D 3 HOH 20 104 324 HOH HOH P . |
| |
| loop_ |
| _pdbx_unobs_or_zero_occ_atoms.id |
| _pdbx_unobs_or_zero_occ_atoms.PDB_model_num |
| _pdbx_unobs_or_zero_occ_atoms.polymer_flag |
| _pdbx_unobs_or_zero_occ_atoms.occupancy_flag |
| _pdbx_unobs_or_zero_occ_atoms.auth_asym_id |
| _pdbx_unobs_or_zero_occ_atoms.auth_comp_id |
| _pdbx_unobs_or_zero_occ_atoms.auth_seq_id |
| _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code |
| _pdbx_unobs_or_zero_occ_atoms.auth_atom_id |
| _pdbx_unobs_or_zero_occ_atoms.label_alt_id |
| _pdbx_unobs_or_zero_occ_atoms.label_asym_id |
| _pdbx_unobs_or_zero_occ_atoms.label_comp_id |
| _pdbx_unobs_or_zero_occ_atoms.label_seq_id |
| _pdbx_unobs_or_zero_occ_atoms.label_atom_id |
| 1 1 Y 1 X GLU 446 ? CG ? A GLU 145 CG |
| 2 1 Y 1 X GLU 446 ? CD ? A GLU 145 CD |
| 3 1 Y 1 X GLU 446 ? OE1 ? A GLU 145 OE1 |
| 4 1 Y 1 X GLU 446 ? OE2 ? A GLU 145 OE2 |
| 5 1 Y 1 X ARG 447 ? CG ? A ARG 146 CG |
| 6 1 Y 1 X ARG 447 ? CD ? A ARG 146 CD |
| 7 1 Y 1 X ARG 447 ? NE ? A ARG 146 NE |
| 8 1 Y 1 X ARG 447 ? CZ ? A ARG 146 CZ |
| 9 1 Y 1 X ARG 447 ? NH1 ? A ARG 146 NH1 |
| 10 1 Y 1 X ARG 447 ? NH2 ? A ARG 146 NH2 |
| 11 1 Y 1 X GLU 493 ? CG ? A GLU 192 CG |
| 12 1 Y 1 X GLU 493 ? CD ? A GLU 192 CD |
| 13 1 Y 1 X GLU 493 ? OE1 ? A GLU 192 OE1 |
| 14 1 Y 1 X GLU 493 ? OE2 ? A GLU 192 OE2 |
| 15 1 Y 1 X GLN 528 ? CG ? A GLN 227 CG |
| 16 1 Y 1 X GLN 528 ? CD ? A GLN 227 CD |
| 17 1 Y 1 X GLN 528 ? OE1 ? A GLN 227 OE1 |
| 18 1 Y 1 X GLN 528 ? NE2 ? A GLN 227 NE2 |
| 19 1 Y 1 X LYS 551 ? CG ? A LYS 250 CG |
| 20 1 Y 1 X LYS 551 ? CD ? A LYS 250 CD |
| 21 1 Y 1 X LYS 551 ? CE ? A LYS 250 CE |
| 22 1 Y 1 X LYS 551 ? NZ ? A LYS 250 NZ |
| 23 1 Y 1 P GLU 78 ? CG ? B GLU 10 CG |
| 24 1 Y 1 P GLU 78 ? CD ? B GLU 10 CD |
| 25 1 Y 1 P GLU 78 ? OE1 ? B GLU 10 OE1 |
| 26 1 Y 1 P GLU 78 ? OE2 ? B GLU 10 OE2 |
| |
| loop_ |
| _software.name |
| _software.classification |
| _software.version |
| _software.citation_id |
| _software.pdbx_ordinal |
| REFMAC refinement 5.2.0005 ? 1 |
| d*TREK 'data scaling' . ? 2 |
| MOLREP phasing . ? 3 |
| |
| _cell.entry_id 2FLU |
| _cell.length_a 76.757 |
| _cell.length_b 92.069 |
| _cell.length_c 46.314 |
| _cell.angle_alpha 90.00 |
| _cell.angle_beta 90.00 |
| _cell.angle_gamma 90.00 |
| _cell.Z_PDB 4 |
| _cell.pdbx_unique_axis ? |
| _cell.length_a_esd ? |
| _cell.length_b_esd ? |
| _cell.length_c_esd ? |
| _cell.angle_alpha_esd ? |
| _cell.angle_beta_esd ? |
| _cell.angle_gamma_esd ? |
| |
| _symmetry.entry_id 2FLU |
| _symmetry.space_group_name_H-M 'P 21 21 2' |
| _symmetry.pdbx_full_space_group_name_H-M ? |
| _symmetry.cell_setting ? |
| _symmetry.Int_Tables_number 18 |
| _symmetry.space_group_name_Hall ? |
| |
| _exptl.entry_id 2FLU |
| _exptl.method 'X-RAY DIFFRACTION' |
| _exptl.crystals_number 1 |
| |
| _exptl_crystal.id 1 |
| _exptl_crystal.density_meas ? |
| _exptl_crystal.density_Matthews 2.30 |
| _exptl_crystal.density_percent_sol 46.49 |
| _exptl_crystal.description ? |
| _exptl_crystal.F_000 ? |
| _exptl_crystal.preparation ? |
| |
| _exptl_crystal_grow.crystal_id 1 |
| _exptl_crystal_grow.method 'VAPOR DIFFUSION' |
| _exptl_crystal_grow.temp 277 |
| _exptl_crystal_grow.temp_details ? |
| _exptl_crystal_grow.pH 8.5 |
| _exptl_crystal_grow.pdbx_details '100 mM TrisHCl 200 mM MgCl2 30% PEG 4000, pH 8.5, VAPOR DIFFUSION, temperature 277K' |
| _exptl_crystal_grow.pdbx_pH_range . |
| |
| _diffrn.id 1 |
| _diffrn.ambient_temp 110 |
| _diffrn.ambient_temp_details ? |
| _diffrn.crystal_id 1 |
| |
| _diffrn_detector.diffrn_id 1 |
| _diffrn_detector.detector CCD |
| _diffrn_detector.type ? |
| _diffrn_detector.pdbx_collection_date ? |
| _diffrn_detector.details ? |
| |
| _diffrn_radiation.diffrn_id 1 |
| _diffrn_radiation.wavelength_id 1 |
| _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M |
| _diffrn_radiation.monochromator ? |
| _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' |
| _diffrn_radiation.pdbx_scattering_type x-ray |
| |
| _diffrn_radiation_wavelength.id 1 |
| _diffrn_radiation_wavelength.wavelength 1.23983 |
| _diffrn_radiation_wavelength.wt 1.0 |
| |
| _diffrn_source.diffrn_id 1 |
| _diffrn_source.source SYNCHROTRON |
| _diffrn_source.type 'ALS BEAMLINE 4.2.2' |
| _diffrn_source.pdbx_synchrotron_site ALS |
| _diffrn_source.pdbx_synchrotron_beamline 4.2.2 |
| _diffrn_source.pdbx_wavelength ? |
| _diffrn_source.pdbx_wavelength_list 1.23983 |
| |
| _reflns.entry_id 2FLU |
| _reflns.observed_criterion_sigma_I 0 |
| _reflns.observed_criterion_sigma_F 0 |
| _reflns.d_resolution_low 36.4 |
| _reflns.d_resolution_high 1.5 |
| _reflns.number_obs 50551 |
| _reflns.number_all ? |
| _reflns.percent_possible_obs 94.7 |
| _reflns.pdbx_Rmerge_I_obs 0.077 |
| _reflns.pdbx_Rsym_value ? |
| _reflns.pdbx_netI_over_sigmaI 11.1 |
| _reflns.B_iso_Wilson_estimate ? |
| _reflns.pdbx_redundancy 6.3 |
| _reflns.R_free_details ? |
| _reflns.limit_h_max ? |
| _reflns.limit_h_min ? |
| _reflns.limit_k_max ? |
| _reflns.limit_k_min ? |
| _reflns.limit_l_max ? |
| _reflns.limit_l_min ? |
| _reflns.observed_criterion_F_max ? |
| _reflns.observed_criterion_F_min ? |
| _reflns.pdbx_chi_squared ? |
| _reflns.pdbx_scaling_rejects ? |
| _reflns.pdbx_ordinal 1 |
| _reflns.pdbx_diffrn_id 1 |
| |
| _reflns_shell.d_res_high 1.50 |
| _reflns_shell.d_res_low 1.55 |
| _reflns_shell.percent_possible_all 64.6 |
| _reflns_shell.Rmerge_I_obs 0.456 |
| _reflns_shell.pdbx_Rsym_value ? |
| _reflns_shell.meanI_over_sigI_obs 2.1 |
| _reflns_shell.pdbx_redundancy 3.3 |
| _reflns_shell.percent_possible_obs ? |
| _reflns_shell.number_unique_all ? |
| _reflns_shell.number_measured_all ? |
| _reflns_shell.number_measured_obs ? |
| _reflns_shell.number_unique_obs ? |
| _reflns_shell.pdbx_chi_squared ? |
| _reflns_shell.pdbx_ordinal 1 |
| _reflns_shell.pdbx_diffrn_id 1 |
| |
| _refine.entry_id 2FLU |
| _refine.ls_number_reflns_obs 47967 |
| _refine.ls_number_reflns_all 50551 |
| _refine.pdbx_ls_sigma_I 0 |
| _refine.pdbx_ls_sigma_F 0 |
| _refine.pdbx_data_cutoff_high_absF ? |
| _refine.pdbx_data_cutoff_low_absF ? |
| _refine.pdbx_data_cutoff_high_rms_absF ? |
| _refine.ls_d_res_low 36.00 |
| _refine.ls_d_res_high 1.50 |
| _refine.ls_percent_reflns_obs 94.66 |
| _refine.ls_R_factor_obs 0.18048 |
| _refine.ls_R_factor_all ? |
| _refine.ls_R_factor_R_work 0.17948 |
| _refine.ls_R_factor_R_free 0.19867 |
| _refine.ls_R_factor_R_free_error ? |
| _refine.ls_R_factor_R_free_error_details ? |
| _refine.ls_percent_reflns_R_free 5.1 |
| _refine.ls_number_reflns_R_free 2576 |
| _refine.ls_number_parameters ? |
| _refine.ls_number_restraints ? |
| _refine.occupancy_min ? |
| _refine.occupancy_max ? |
| _refine.correlation_coeff_Fo_to_Fc 0.967 |
| _refine.correlation_coeff_Fo_to_Fc_free 0.958 |
| _refine.B_iso_mean 18.535 |
| _refine.aniso_B[1][1] 0.07 |
| _refine.aniso_B[2][2] -0.80 |
| _refine.aniso_B[3][3] 0.73 |
| _refine.aniso_B[1][2] 0.00 |
| _refine.aniso_B[1][3] 0.00 |
| _refine.aniso_B[2][3] 0.00 |
| _refine.solvent_model_details MASK |
| _refine.solvent_model_param_ksol ? |
| _refine.solvent_model_param_bsol ? |
| _refine.pdbx_solvent_vdw_probe_radii 1.20 |
| _refine.pdbx_solvent_ion_probe_radii 0.80 |
| _refine.pdbx_solvent_shrinkage_radii 0.80 |
| _refine.pdbx_ls_cross_valid_method THROUGHOUT |
| _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' |
| _refine.pdbx_starting_model 1U6D |
| _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' |
| _refine.pdbx_isotropic_thermal_model ? |
| _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' |
| _refine.pdbx_stereochem_target_val_spec_case ? |
| _refine.pdbx_R_Free_selection_details RANDOM |
| _refine.pdbx_overall_ESU_R 0.076 |
| _refine.pdbx_overall_ESU_R_Free 0.074 |
| _refine.overall_SU_ML 0.047 |
| _refine.overall_SU_B 2.491 |
| _refine.ls_redundancy_reflns_obs ? |
| _refine.B_iso_min ? |
| _refine.B_iso_max ? |
| _refine.overall_SU_R_Cruickshank_DPI ? |
| _refine.overall_SU_R_free ? |
| _refine.ls_wR_factor_R_free ? |
| _refine.ls_wR_factor_R_work ? |
| _refine.overall_FOM_free_R_set ? |
| _refine.overall_FOM_work_R_set ? |
| _refine.pdbx_refine_id 'X-RAY DIFFRACTION' |
| _refine.pdbx_TLS_residual_ADP_flag 'LIKELY RESIDUAL' |
| _refine.pdbx_diffrn_id 1 |
| _refine.pdbx_overall_phase_error ? |
| _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? |
| _refine.pdbx_overall_SU_R_Blow_DPI ? |
| _refine.pdbx_overall_SU_R_free_Blow_DPI ? |
| |
| _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' |
| _refine_hist.cycle_id LAST |
| _refine_hist.pdbx_number_atoms_protein 2300 |
| _refine_hist.pdbx_number_atoms_nucleic_acid 0 |
| _refine_hist.pdbx_number_atoms_ligand 0 |
| _refine_hist.number_atoms_solvent 333 |
| _refine_hist.number_atoms_total 2633 |
| _refine_hist.d_res_high 1.50 |
| _refine_hist.d_res_low 36.00 |
| |
| loop_ |
| _refine_ls_restr.type |
| _refine_ls_restr.dev_ideal |
| _refine_ls_restr.dev_ideal_target |
| _refine_ls_restr.weight |
| _refine_ls_restr.number |
| _refine_ls_restr.pdbx_refine_id |
| _refine_ls_restr.pdbx_restraint_function |
| r_bond_refined_d 0.009 0.021 ? 2468 'X-RAY DIFFRACTION' ? |
| r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_angle_refined_deg 1.211 1.937 ? 3389 'X-RAY DIFFRACTION' ? |
| r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_dihedral_angle_1_deg 6.559 5.000 ? 335 'X-RAY DIFFRACTION' ? |
| r_dihedral_angle_2_deg 33.462 22.521 ? 119 'X-RAY DIFFRACTION' ? |
| r_dihedral_angle_3_deg 10.892 15.000 ? 370 'X-RAY DIFFRACTION' ? |
| r_dihedral_angle_4_deg 20.823 15.000 ? 25 'X-RAY DIFFRACTION' ? |
| r_chiral_restr 0.088 0.200 ? 368 'X-RAY DIFFRACTION' ? |
| r_gen_planes_refined 0.005 0.020 ? 1972 'X-RAY DIFFRACTION' ? |
| r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_nbd_refined 0.194 0.200 ? 1149 'X-RAY DIFFRACTION' ? |
| r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_nbtor_refined 0.302 0.200 ? 1728 'X-RAY DIFFRACTION' ? |
| r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_xyhbond_nbd_refined 0.105 0.200 ? 294 'X-RAY DIFFRACTION' ? |
| r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_symmetry_vdw_refined 0.241 0.200 ? 45 'X-RAY DIFFRACTION' ? |
| r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_symmetry_hbond_refined 0.126 0.200 ? 26 'X-RAY DIFFRACTION' ? |
| r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_mcbond_it 0.724 1.500 ? 1578 'X-RAY DIFFRACTION' ? |
| r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_mcangle_it 1.175 2.000 ? 2481 'X-RAY DIFFRACTION' ? |
| r_scbond_it 1.869 3.000 ? 1030 'X-RAY DIFFRACTION' ? |
| r_scangle_it 2.695 4.500 ? 891 'X-RAY DIFFRACTION' ? |
| r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? |
| r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? |
| |
| _refine_ls_shell.pdbx_total_number_of_bins_used 20 |
| _refine_ls_shell.d_res_high 1.500 |
| _refine_ls_shell.d_res_low 1.539 |
| _refine_ls_shell.number_reflns_R_work 2295 |
| _refine_ls_shell.R_factor_R_work 0.307 |
| _refine_ls_shell.percent_reflns_obs 62.22 |
| _refine_ls_shell.R_factor_R_free 0.33 |
| _refine_ls_shell.R_factor_R_free_error ? |
| _refine_ls_shell.percent_reflns_R_free ? |
| _refine_ls_shell.number_reflns_R_free 131 |
| _refine_ls_shell.number_reflns_all ? |
| _refine_ls_shell.R_factor_all ? |
| _refine_ls_shell.number_reflns_obs ? |
| _refine_ls_shell.redundancy_reflns_obs ? |
| _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' |
| |
| _database_PDB_matrix.entry_id 2FLU |
| _database_PDB_matrix.origx[1][1] 1.000000 |
| _database_PDB_matrix.origx[1][2] 0.000000 |
| _database_PDB_matrix.origx[1][3] 0.000000 |
| _database_PDB_matrix.origx[2][1] 0.000000 |
| _database_PDB_matrix.origx[2][2] 1.000000 |
| _database_PDB_matrix.origx[2][3] 0.000000 |
| _database_PDB_matrix.origx[3][1] 0.000000 |
| _database_PDB_matrix.origx[3][2] 0.000000 |
| _database_PDB_matrix.origx[3][3] 1.000000 |
| _database_PDB_matrix.origx_vector[1] 0.00000 |
| _database_PDB_matrix.origx_vector[2] 0.00000 |
| _database_PDB_matrix.origx_vector[3] 0.00000 |
| |
| _struct.entry_id 2FLU |
| _struct.title 'Crystal Structure of the Kelch-Neh2 Complex' |
| _struct.pdbx_model_details ? |
| _struct.pdbx_CASP_flag ? |
| _struct.pdbx_model_type_details ? |
| |
| _struct_keywords.entry_id 2FLU |
| _struct_keywords.pdbx_keywords LIGASE |
| _struct_keywords.text 'Kelch domain, protein-peptide complex, beta-propeller, LIGASE' |
| |
| loop_ |
| _struct_asym.id |
| _struct_asym.pdbx_blank_PDB_chainid_flag |
| _struct_asym.pdbx_modified |
| _struct_asym.entity_id |
| _struct_asym.details |
| A N N 1 ? |
| B N N 2 ? |
| C N N 3 ? |
| D N N 3 ? |
| |
| loop_ |
| _struct_ref.id |
| _struct_ref.db_name |
| _struct_ref.db_code |
| _struct_ref.pdbx_db_accession |
| _struct_ref.entity_id |
| _struct_ref.pdbx_seq_one_letter_code |
| _struct_ref.pdbx_align_begin |
| _struct_ref.pdbx_db_isoform |
| 1 GB AAH15945 16198527 1 |
| ;APKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMT |
| NQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDG |
| TNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGIT |
| VHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT |
| ; |
| 321 ? |
| 2 UNP NF2L2_HUMAN Q16236 2 AFFAQLQLDEETGEFL 69 ? |
| |
| loop_ |
| _struct_ref_seq.align_id |
| _struct_ref_seq.ref_id |
| _struct_ref_seq.pdbx_PDB_id_code |
| _struct_ref_seq.pdbx_strand_id |
| _struct_ref_seq.seq_align_beg |
| _struct_ref_seq.pdbx_seq_align_beg_ins_code |
| _struct_ref_seq.seq_align_end |
| _struct_ref_seq.pdbx_seq_align_end_ins_code |
| _struct_ref_seq.pdbx_db_accession |
| _struct_ref_seq.db_align_beg |
| _struct_ref_seq.pdbx_db_align_beg_ins_code |
| _struct_ref_seq.db_align_end |
| _struct_ref_seq.pdbx_db_align_end_ins_code |
| _struct_ref_seq.pdbx_auth_seq_align_beg |
| _struct_ref_seq.pdbx_auth_seq_align_end |
| 1 1 2FLU X 20 ? 308 ? 16198527 321 ? 609 ? 321 609 |
| 2 2 2FLU P 1 ? 16 ? Q16236 69 ? 84 ? 69 84 |
| |
| loop_ |
| _struct_ref_seq_dif.align_id |
| _struct_ref_seq_dif.pdbx_pdb_id_code |
| _struct_ref_seq_dif.mon_id |
| _struct_ref_seq_dif.pdbx_pdb_strand_id |
| _struct_ref_seq_dif.seq_num |
| _struct_ref_seq_dif.pdbx_pdb_ins_code |
| _struct_ref_seq_dif.pdbx_seq_db_name |
| _struct_ref_seq_dif.pdbx_seq_db_accession_code |
| _struct_ref_seq_dif.db_mon_id |
| _struct_ref_seq_dif.pdbx_seq_db_seq_num |
| _struct_ref_seq_dif.details |
| _struct_ref_seq_dif.pdbx_auth_seq_num |
| _struct_ref_seq_dif.pdbx_ordinal |
| 1 2FLU GLY X 1 ? GB 16198527 ? ? 'expression tag' 302 1 |
| 1 2FLU SER X 2 ? GB 16198527 ? ? 'expression tag' 303 2 |
| 1 2FLU SER X 3 ? GB 16198527 ? ? 'expression tag' 304 3 |
| 1 2FLU HIS X 4 ? GB 16198527 ? ? 'expression tag' 305 4 |
| 1 2FLU HIS X 5 ? GB 16198527 ? ? 'expression tag' 306 5 |
| 1 2FLU HIS X 6 ? GB 16198527 ? ? 'expression tag' 307 6 |
| 1 2FLU HIS X 7 ? GB 16198527 ? ? 'expression tag' 308 7 |
| 1 2FLU HIS X 8 ? GB 16198527 ? ? 'expression tag' 309 8 |
| 1 2FLU HIS X 9 ? GB 16198527 ? ? 'expression tag' 310 9 |
| 1 2FLU SER X 10 ? GB 16198527 ? ? 'cloning artifact' 311 10 |
| 1 2FLU SER X 11 ? GB 16198527 ? ? 'cloning artifact' 312 11 |
| 1 2FLU GLY X 12 ? GB 16198527 ? ? 'cloning artifact' 313 12 |
| 1 2FLU LEU X 13 ? GB 16198527 ? ? 'cloning artifact' 314 13 |
| 1 2FLU VAL X 14 ? GB 16198527 ? ? 'cloning artifact' 315 14 |
| 1 2FLU PRO X 15 ? GB 16198527 ? ? 'cloning artifact' 316 15 |
| 1 2FLU ARG X 16 ? GB 16198527 ? ? 'cloning artifact' 317 16 |
| 1 2FLU GLY X 17 ? GB 16198527 ? ? 'cloning artifact' 318 17 |
| 1 2FLU SER X 18 ? GB 16198527 ? ? 'cloning artifact' 319 18 |
| 1 2FLU HIS X 19 ? GB 16198527 ? ? 'cloning artifact' 320 19 |
| |
| _pdbx_struct_assembly.id 1 |
| _pdbx_struct_assembly.details author_defined_assembly |
| _pdbx_struct_assembly.method_details ? |
| _pdbx_struct_assembly.oligomeric_details dimeric |
| _pdbx_struct_assembly.oligomeric_count 2 |
| |
| _pdbx_struct_assembly_gen.assembly_id 1 |
| _pdbx_struct_assembly_gen.oper_expression 1 |
| _pdbx_struct_assembly_gen.asym_id_list A,B,C,D |
| |
| _pdbx_struct_oper_list.id 1 |
| _pdbx_struct_oper_list.type 'identity operation' |
| _pdbx_struct_oper_list.name 1_555 |
| _pdbx_struct_oper_list.symmetry_operation x,y,z |
| _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 |
| _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 |
| _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 |
| _pdbx_struct_oper_list.vector[1] 0.0000000000 |
| _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 |
| _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 |
| _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 |
| _pdbx_struct_oper_list.vector[2] 0.0000000000 |
| _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 |
| _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 |
| _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 |
| _pdbx_struct_oper_list.vector[3] 0.0000000000 |
| |
| _struct_biol.id 1 |
| |
| _struct_conn.id disulf1 |
| _struct_conn.conn_type_id disulf |
| _struct_conn.pdbx_leaving_atom_flag ? |
| _struct_conn.pdbx_PDB_id ? |
| _struct_conn.ptnr1_label_asym_id A |
| _struct_conn.ptnr1_label_comp_id CYS |
| _struct_conn.ptnr1_label_seq_id 133 |
| _struct_conn.ptnr1_label_atom_id SG |
| _struct_conn.pdbx_ptnr1_label_alt_id A |
| _struct_conn.pdbx_ptnr1_PDB_ins_code ? |
| _struct_conn.pdbx_ptnr1_standard_comp_id ? |
| _struct_conn.ptnr1_symmetry 1_555 |
| _struct_conn.ptnr2_label_asym_id A |
| _struct_conn.ptnr2_label_comp_id CYS |
| _struct_conn.ptnr2_label_seq_id 217 |
| _struct_conn.ptnr2_label_atom_id SG |
| _struct_conn.pdbx_ptnr2_label_alt_id ? |
| _struct_conn.pdbx_ptnr2_PDB_ins_code ? |
| _struct_conn.ptnr1_auth_asym_id X |
| _struct_conn.ptnr1_auth_comp_id CYS |
| _struct_conn.ptnr1_auth_seq_id 434 |
| _struct_conn.ptnr2_auth_asym_id X |
| _struct_conn.ptnr2_auth_comp_id CYS |
| _struct_conn.ptnr2_auth_seq_id 518 |
| _struct_conn.ptnr2_symmetry 4_455 |
| _struct_conn.pdbx_ptnr3_label_atom_id ? |
| _struct_conn.pdbx_ptnr3_label_seq_id ? |
| _struct_conn.pdbx_ptnr3_label_comp_id ? |
| _struct_conn.pdbx_ptnr3_label_asym_id ? |
| _struct_conn.pdbx_ptnr3_label_alt_id ? |
| _struct_conn.pdbx_ptnr3_PDB_ins_code ? |
| _struct_conn.details ? |
| _struct_conn.pdbx_dist_value 2.901 |
| _struct_conn.pdbx_value_order ? |
| _struct_conn.pdbx_role ? |
| |
| _struct_conn_type.id disulf |
| _struct_conn_type.criteria ? |
| _struct_conn_type.reference ? |
| |
| _pdbx_modification_feature.ordinal 1 |
| _pdbx_modification_feature.label_comp_id CYS |
| _pdbx_modification_feature.label_asym_id A |
| _pdbx_modification_feature.label_seq_id 133 |
| _pdbx_modification_feature.label_alt_id A |
| _pdbx_modification_feature.modified_residue_label_comp_id CYS |
| _pdbx_modification_feature.modified_residue_label_asym_id A |
| _pdbx_modification_feature.modified_residue_label_seq_id 217 |
| _pdbx_modification_feature.modified_residue_label_alt_id ? |
| _pdbx_modification_feature.auth_comp_id CYS |
| _pdbx_modification_feature.auth_asym_id X |
| _pdbx_modification_feature.auth_seq_id 434 |
| _pdbx_modification_feature.PDB_ins_code ? |
| _pdbx_modification_feature.symmetry 1_555 |
| _pdbx_modification_feature.modified_residue_auth_comp_id CYS |
| _pdbx_modification_feature.modified_residue_auth_asym_id X |
| _pdbx_modification_feature.modified_residue_auth_seq_id 518 |
| _pdbx_modification_feature.modified_residue_PDB_ins_code ? |
| _pdbx_modification_feature.modified_residue_symmetry 4_455 |
| _pdbx_modification_feature.comp_id_linking_atom SG |
| _pdbx_modification_feature.modified_residue_id_linking_atom SG |
| _pdbx_modification_feature.modified_residue_id . |
| _pdbx_modification_feature.ref_pcm_id . |
| _pdbx_modification_feature.ref_comp_id . |
| _pdbx_modification_feature.type None |
| _pdbx_modification_feature.category 'Disulfide bridge' |
| |
| loop_ |
| _struct_sheet.id |
| _struct_sheet.type |
| _struct_sheet.number_strands |
| _struct_sheet.details |
| A ? 4 ? |
| B ? 4 ? |
| C ? 2 ? |
| D ? 4 ? |
| E ? 2 ? |
| F ? 4 ? |
| G ? 4 ? |
| H ? 4 ? |
| I ? 2 ? |
| |
| loop_ |
| _struct_sheet_order.sheet_id |
| _struct_sheet_order.range_id_1 |
| _struct_sheet_order.range_id_2 |
| _struct_sheet_order.offset |
| _struct_sheet_order.sense |
| A 1 2 ? anti-parallel |
| A 2 3 ? anti-parallel |
| A 3 4 ? anti-parallel |
| B 1 2 ? anti-parallel |
| B 2 3 ? anti-parallel |
| B 3 4 ? anti-parallel |
| C 1 2 ? anti-parallel |
| D 1 2 ? anti-parallel |
| D 2 3 ? anti-parallel |
| D 3 4 ? anti-parallel |
| E 1 2 ? anti-parallel |
| F 1 2 ? anti-parallel |
| F 2 3 ? anti-parallel |
| F 3 4 ? anti-parallel |
| G 1 2 ? anti-parallel |
| G 2 3 ? anti-parallel |
| G 3 4 ? anti-parallel |
| H 1 2 ? anti-parallel |
| H 2 3 ? anti-parallel |
| H 3 4 ? anti-parallel |
| I 1 2 ? anti-parallel |
| |
| loop_ |
| _struct_sheet_range.sheet_id |
| _struct_sheet_range.id |
| _struct_sheet_range.beg_label_comp_id |
| _struct_sheet_range.beg_label_asym_id |
| _struct_sheet_range.beg_label_seq_id |
| _struct_sheet_range.pdbx_beg_PDB_ins_code |
| _struct_sheet_range.end_label_comp_id |
| _struct_sheet_range.end_label_asym_id |
| _struct_sheet_range.end_label_seq_id |
| _struct_sheet_range.pdbx_end_PDB_ins_code |
| _struct_sheet_range.beg_auth_comp_id |
| _struct_sheet_range.beg_auth_asym_id |
| _struct_sheet_range.beg_auth_seq_id |
| _struct_sheet_range.end_auth_comp_id |
| _struct_sheet_range.end_auth_asym_id |
| _struct_sheet_range.end_auth_seq_id |
| A 1 TRP A 51 ? ARG A 53 ? TRP X 352 ARG X 354 |
| A 2 LEU A 41 ? TYR A 44 ? LEU X 342 TYR X 345 |
| A 3 LEU A 26 ? ALA A 30 ? LEU X 327 ALA X 331 |
| A 4 GLY A 304 ? THR A 308 ? GLY X 605 THR X 609 |
| B 1 ALA A 65 ? VAL A 69 ? ALA X 366 VAL X 370 |
| B 2 LEU A 72 ? VAL A 76 ? LEU X 373 VAL X 377 |
| B 3 LEU A 92 ? TYR A 95 ? LEU X 393 TYR X 396 |
| B 4 TRP A 102 ? PRO A 104 ? TRP X 403 PRO X 405 |
| C 1 ARG A 79 ? SER A 82 ? ARG X 380 SER X 383 |
| C 2 GLY A 85 ? ASP A 88 ? GLY X 386 ASP X 389 |
| D 1 GLY A 116 ? ILE A 120 ? GLY X 417 ILE X 421 |
| D 2 HIS A 123 ? VAL A 127 ? HIS X 424 VAL X 428 |
| D 3 VAL A 139 ? TYR A 142 ? VAL X 440 TYR X 443 |
| D 4 TRP A 149 ? LEU A 151 ? TRP X 450 LEU X 452 |
| E 1 SER A 130 ? HIS A 131 ? SER X 431 HIS X 432 |
| E 2 ILE A 134 ? HIS A 135 ? ILE X 435 HIS X 436 |
| F 1 GLY A 163 ? LEU A 167 ? GLY X 464 LEU X 468 |
| F 2 LEU A 170 ? VAL A 174 ? LEU X 471 VAL X 475 |
| F 3 ALA A 186 ? TYR A 189 ? ALA X 487 TYR X 490 |
| F 4 TRP A 196 ? MET A 198 ? TRP X 497 MET X 499 |
| G 1 GLY A 210 ? LEU A 214 ? GLY X 511 LEU X 515 |
| G 2 CYS A 217 ? ALA A 221 ? CYS X 518 ALA X 522 |
| G 3 VAL A 233 ? ASP A 237 ? VAL X 534 ASP X 538 |
| G 4 THR A 242 ? PHE A 245 ? THR X 543 PHE X 546 |
| H 1 GLY A 257 ? HIS A 261 ? GLY X 558 HIS X 562 |
| H 2 ARG A 264 ? LEU A 268 ? ARG X 565 LEU X 569 |
| H 3 SER A 279 ? ASP A 284 ? SER X 580 ASP X 585 |
| H 4 THR A 289 ? ARG A 295 ? THR X 590 ARG X 596 |
| I 1 GLN B 7 ? LEU B 8 ? GLN P 75 LEU P 76 |
| I 2 PHE B 15 ? LEU B 16 ? PHE P 83 LEU P 84 |
| |
| loop_ |
| _pdbx_struct_sheet_hbond.sheet_id |
| _pdbx_struct_sheet_hbond.range_id_1 |
| _pdbx_struct_sheet_hbond.range_id_2 |
| _pdbx_struct_sheet_hbond.range_1_label_atom_id |
| _pdbx_struct_sheet_hbond.range_1_label_comp_id |
| _pdbx_struct_sheet_hbond.range_1_label_asym_id |
| _pdbx_struct_sheet_hbond.range_1_label_seq_id |
| _pdbx_struct_sheet_hbond.range_1_PDB_ins_code |
| _pdbx_struct_sheet_hbond.range_1_auth_atom_id |
| _pdbx_struct_sheet_hbond.range_1_auth_comp_id |
| _pdbx_struct_sheet_hbond.range_1_auth_asym_id |
| _pdbx_struct_sheet_hbond.range_1_auth_seq_id |
| _pdbx_struct_sheet_hbond.range_2_label_atom_id |
| _pdbx_struct_sheet_hbond.range_2_label_comp_id |
| _pdbx_struct_sheet_hbond.range_2_label_asym_id |
| _pdbx_struct_sheet_hbond.range_2_label_seq_id |
| _pdbx_struct_sheet_hbond.range_2_PDB_ins_code |
| _pdbx_struct_sheet_hbond.range_2_auth_atom_id |
| _pdbx_struct_sheet_hbond.range_2_auth_comp_id |
| _pdbx_struct_sheet_hbond.range_2_auth_asym_id |
| _pdbx_struct_sheet_hbond.range_2_auth_seq_id |
| A 1 2 O LEU A 52 ? O LEU X 353 N ALA A 43 ? N ALA X 344 |
| A 2 3 O TYR A 44 ? O TYR X 345 N ILE A 27 ? N ILE X 328 |
| A 3 4 N TYR A 28 ? N TYR X 329 O ALA A 306 ? O ALA X 607 |
| B 1 2 N CYS A 67 ? N CYS X 368 O TYR A 74 ? O TYR X 375 |
| B 2 3 N LEU A 73 ? N LEU X 374 O TYR A 95 ? O TYR X 396 |
| B 3 4 N CYS A 94 ? N CYS X 395 O SER A 103 ? O SER X 404 |
| C 1 2 N ASN A 80 ? N ASN X 381 O THR A 87 ? O THR X 388 |
| D 1 2 N GLY A 118 ? N GLY X 419 O TYR A 125 ? O TYR X 426 |
| D 2 3 N ALA A 126 ? N ALA X 427 O GLU A 140 ? O GLU X 441 |
| D 3 4 N ARG A 141 ? N ARG X 442 O HIS A 150 ? O HIS X 451 |
| E 1 2 N HIS A 131 ? N HIS X 432 O ILE A 134 ? O ILE X 435 |
| F 1 2 N ALA A 165 ? N ALA X 466 O TYR A 172 ? O TYR X 473 |
| F 2 3 N LEU A 171 ? N LEU X 472 O TYR A 189 ? O TYR X 490 |
| F 3 4 N CYS A 188 ? N CYS X 489 O ARG A 197 ? O ARG X 498 |
| G 1 2 N CYS A 212 ? N CYS X 513 O TYR A 219 ? O TYR X 520 |
| G 2 3 N ILE A 218 ? N ILE X 519 O TYR A 236 ? O TYR X 537 |
| G 3 4 N ARG A 235 ? N ARG X 536 O THR A 244 ? O THR X 545 |
| H 1 2 N THR A 259 ? N THR X 560 O TYR A 266 ? O TYR X 567 |
| H 2 3 N ILE A 265 ? N ILE X 566 O TYR A 283 ? O TYR X 584 |
| H 3 4 N CYS A 282 ? N CYS X 583 O SER A 291 ? O SER X 592 |
| I 1 2 N GLN B 7 ? N GLN P 75 O LEU B 16 ? O LEU P 84 |
| |
| _pdbx_entry_details.entry_id 2FLU |
| _pdbx_entry_details.compound_details ? |
| _pdbx_entry_details.source_details ? |
| _pdbx_entry_details.nonpolymer_details ? |
| _pdbx_entry_details.sequence_details ? |
| _pdbx_entry_details.has_ligand_of_interest ? |
| _pdbx_entry_details.has_protein_modification Y |
| |
| loop_ |
| _pdbx_validate_torsion.id |
| _pdbx_validate_torsion.PDB_model_num |
| _pdbx_validate_torsion.auth_comp_id |
| _pdbx_validate_torsion.auth_asym_id |
| _pdbx_validate_torsion.auth_seq_id |
| _pdbx_validate_torsion.PDB_ins_code |
| _pdbx_validate_torsion.label_alt_id |
| _pdbx_validate_torsion.phi |
| _pdbx_validate_torsion.psi |
| 1 1 ARG X 336 ? ? 68.77 -27.83 |
| 2 1 ARG X 336 ? ? 72.40 -31.85 |
| 3 1 GLN X 528 ? ? -130.73 -38.96 |
| 4 1 VAL X 547 ? ? -113.62 -168.84 |
| |
| loop_ |
| _pdbx_refine_tls.id |
| _pdbx_refine_tls.details |
| _pdbx_refine_tls.method |
| _pdbx_refine_tls.origin_x |
| _pdbx_refine_tls.origin_y |
| _pdbx_refine_tls.origin_z |
| _pdbx_refine_tls.T[1][1] |
| _pdbx_refine_tls.T[2][2] |
| _pdbx_refine_tls.T[3][3] |
| _pdbx_refine_tls.T[1][2] |
| _pdbx_refine_tls.T[1][3] |
| _pdbx_refine_tls.T[2][3] |
| _pdbx_refine_tls.L[1][1] |
| _pdbx_refine_tls.L[2][2] |
| _pdbx_refine_tls.L[3][3] |
| _pdbx_refine_tls.L[1][2] |
| _pdbx_refine_tls.L[1][3] |
| _pdbx_refine_tls.L[2][3] |
| _pdbx_refine_tls.S[1][1] |
| _pdbx_refine_tls.S[1][2] |
| _pdbx_refine_tls.S[1][3] |
| _pdbx_refine_tls.S[2][1] |
| _pdbx_refine_tls.S[2][2] |
| _pdbx_refine_tls.S[2][3] |
| _pdbx_refine_tls.S[3][1] |
| _pdbx_refine_tls.S[3][2] |
| _pdbx_refine_tls.S[3][3] |
| _pdbx_refine_tls.pdbx_refine_id |
| 1 ? refined 17.6561 16.8055 7.1613 -0.0139 -0.0197 -0.0133 -0.0126 -0.0115 -0.0062 0.2606 0.4950 0.2986 -0.0344 -0.1369 -0.1056 |
| 0.0037 -0.0063 0.0072 0.0325 -0.0032 -0.0117 -0.0108 0.0169 -0.0005 'X-RAY DIFFRACTION' |
| 2 ? refined -2.2216 6.2002 1.7986 -0.0151 0.0017 0.0159 -0.0139 0.0009 0.0219 5.9313 0.3255 0.0761 0.9313 -0.1737 0.0856 |
| -0.0159 0.1740 0.0752 0.0172 0.0628 0.0664 -0.0909 0.0298 -0.0469 'X-RAY DIFFRACTION' |
| |
| loop_ |
| _pdbx_refine_tls_group.id |
| _pdbx_refine_tls_group.refine_tls_id |
| _pdbx_refine_tls_group.beg_auth_asym_id |
| _pdbx_refine_tls_group.beg_auth_seq_id |
| _pdbx_refine_tls_group.beg_label_asym_id |
| _pdbx_refine_tls_group.beg_label_seq_id |
| _pdbx_refine_tls_group.end_auth_asym_id |
| _pdbx_refine_tls_group.end_auth_seq_id |
| _pdbx_refine_tls_group.end_label_asym_id |
| _pdbx_refine_tls_group.end_label_seq_id |
| _pdbx_refine_tls_group.selection |
| _pdbx_refine_tls_group.pdbx_refine_id |
| _pdbx_refine_tls_group.selection_details |
| 1 1 X 325 A 24 X 609 A 308 ? 'X-RAY DIFFRACTION' ? |
| 2 2 P 69 B 1 P 84 B 16 ? 'X-RAY DIFFRACTION' ? |
| |
| loop_ |
| _pdbx_unobs_or_zero_occ_residues.id |
| _pdbx_unobs_or_zero_occ_residues.PDB_model_num |
| _pdbx_unobs_or_zero_occ_residues.polymer_flag |
| _pdbx_unobs_or_zero_occ_residues.occupancy_flag |
| _pdbx_unobs_or_zero_occ_residues.auth_asym_id |
| _pdbx_unobs_or_zero_occ_residues.auth_comp_id |
| _pdbx_unobs_or_zero_occ_residues.auth_seq_id |
| _pdbx_unobs_or_zero_occ_residues.PDB_ins_code |
| _pdbx_unobs_or_zero_occ_residues.label_asym_id |
| _pdbx_unobs_or_zero_occ_residues.label_comp_id |
| _pdbx_unobs_or_zero_occ_residues.label_seq_id |
| 1 1 Y 1 X GLY 302 ? A GLY 1 |
| 2 1 Y 1 X SER 303 ? A SER 2 |
| 3 1 Y 1 X SER 304 ? A SER 3 |
| 4 1 Y 1 X HIS 305 ? A HIS 4 |
| 5 1 Y 1 X HIS 306 ? A HIS 5 |
| 6 1 Y 1 X HIS 307 ? A HIS 6 |
| 7 1 Y 1 X HIS 308 ? A HIS 7 |
| 8 1 Y 1 X HIS 309 ? A HIS 8 |
| 9 1 Y 1 X HIS 310 ? A HIS 9 |
| 10 1 Y 1 X SER 311 ? A SER 10 |
| 11 1 Y 1 X SER 312 ? A SER 11 |
| 12 1 Y 1 X GLY 313 ? A GLY 12 |
| 13 1 Y 1 X LEU 314 ? A LEU 13 |
| 14 1 Y 1 X VAL 315 ? A VAL 14 |
| 15 1 Y 1 X PRO 316 ? A PRO 15 |
| 16 1 Y 1 X ARG 317 ? A ARG 16 |
| 17 1 Y 1 X GLY 318 ? A GLY 17 |
| 18 1 Y 1 X SER 319 ? A SER 18 |
| 19 1 Y 1 X HIS 320 ? A HIS 19 |
| 20 1 Y 1 X ALA 321 ? A ALA 20 |
| 21 1 Y 1 X PRO 322 ? A PRO 21 |
| 22 1 Y 1 X LYS 323 ? A LYS 22 |
| 23 1 Y 1 X VAL 324 ? A VAL 23 |
| |
| loop_ |
| _chem_comp_atom.comp_id |
| _chem_comp_atom.atom_id |
| _chem_comp_atom.type_symbol |
| _chem_comp_atom.pdbx_aromatic_flag |
| _chem_comp_atom.pdbx_stereo_config |
| _chem_comp_atom.pdbx_ordinal |
| ALA N N N N 1 |
| ALA CA C N S 2 |
| ALA C C N N 3 |
| ALA O O N N 4 |
| ALA CB C N N 5 |
| ALA OXT O N N 6 |
| ALA H H N N 7 |
| ALA H2 H N N 8 |
| ALA HA H N N 9 |
| ALA HB1 H N N 10 |
| ALA HB2 H N N 11 |
| ALA HB3 H N N 12 |
| ALA HXT H N N 13 |
| ARG N N N N 14 |
| ARG CA C N S 15 |
| ARG C C N N 16 |
| ARG O O N N 17 |
| ARG CB C N N 18 |
| ARG CG C N N 19 |
| ARG CD C N N 20 |
| ARG NE N N N 21 |
| ARG CZ C N N 22 |
| ARG NH1 N N N 23 |
| ARG NH2 N N N 24 |
| ARG OXT O N N 25 |
| ARG H H N N 26 |
| ARG H2 H N N 27 |
| ARG HA H N N 28 |
| ARG HB2 H N N 29 |
| ARG HB3 H N N 30 |
| ARG HG2 H N N 31 |
| ARG HG3 H N N 32 |
| ARG HD2 H N N 33 |
| ARG HD3 H N N 34 |
| ARG HE H N N 35 |
| ARG HH11 H N N 36 |
| ARG HH12 H N N 37 |
| ARG HH21 H N N 38 |
| ARG HH22 H N N 39 |
| ARG HXT H N N 40 |
| ASN N N N N 41 |
| ASN CA C N S 42 |
| ASN C C N N 43 |
| ASN O O N N 44 |
| ASN CB C N N 45 |
| ASN CG C N N 46 |
| ASN OD1 O N N 47 |
| ASN ND2 N N N 48 |
| ASN OXT O N N 49 |
| ASN H H N N 50 |
| ASN H2 H N N 51 |
| ASN HA H N N 52 |
| ASN HB2 H N N 53 |
| ASN HB3 H N N 54 |
| ASN HD21 H N N 55 |
| ASN HD22 H N N 56 |
| ASN HXT H N N 57 |
| ASP N N N N 58 |
| ASP CA C N S 59 |
| ASP C C N N 60 |
| ASP O O N N 61 |
| ASP CB C N N 62 |
| ASP CG C N N 63 |
| ASP OD1 O N N 64 |
| ASP OD2 O N N 65 |
| ASP OXT O N N 66 |
| ASP H H N N 67 |
| ASP H2 H N N 68 |
| ASP HA H N N 69 |
| ASP HB2 H N N 70 |
| ASP HB3 H N N 71 |
| ASP HD2 H N N 72 |
| ASP HXT H N N 73 |
| CYS N N N N 74 |
| CYS CA C N R 75 |
| CYS C C N N 76 |
| CYS O O N N 77 |
| CYS CB C N N 78 |
| CYS SG S N N 79 |
| CYS OXT O N N 80 |
| CYS H H N N 81 |
| CYS H2 H N N 82 |
| CYS HA H N N 83 |
| CYS HB2 H N N 84 |
| CYS HB3 H N N 85 |
| CYS HG H N N 86 |
| CYS HXT H N N 87 |
| GLN N N N N 88 |
| GLN CA C N S 89 |
| GLN C C N N 90 |
| GLN O O N N 91 |
| GLN CB C N N 92 |
| GLN CG C N N 93 |
| GLN CD C N N 94 |
| GLN OE1 O N N 95 |
| GLN NE2 N N N 96 |
| GLN OXT O N N 97 |
| GLN H H N N 98 |
| GLN H2 H N N 99 |
| GLN HA H N N 100 |
| GLN HB2 H N N 101 |
| GLN HB3 H N N 102 |
| GLN HG2 H N N 103 |
| GLN HG3 H N N 104 |
| GLN HE21 H N N 105 |
| GLN HE22 H N N 106 |
| GLN HXT H N N 107 |
| GLU N N N N 108 |
| GLU CA C N S 109 |
| GLU C C N N 110 |
| GLU O O N N 111 |
| GLU CB C N N 112 |
| GLU CG C N N 113 |
| GLU CD C N N 114 |
| GLU OE1 O N N 115 |
| GLU OE2 O N N 116 |
| GLU OXT O N N 117 |
| GLU H H N N 118 |
| GLU H2 H N N 119 |
| GLU HA H N N 120 |
| GLU HB2 H N N 121 |
| GLU HB3 H N N 122 |
| GLU HG2 H N N 123 |
| GLU HG3 H N N 124 |
| GLU HE2 H N N 125 |
| GLU HXT H N N 126 |
| GLY N N N N 127 |
| GLY CA C N N 128 |
| GLY C C N N 129 |
| GLY O O N N 130 |
| GLY OXT O N N 131 |
| GLY H H N N 132 |
| GLY H2 H N N 133 |
| GLY HA2 H N N 134 |
| GLY HA3 H N N 135 |
| GLY HXT H N N 136 |
| HIS N N N N 137 |
| HIS CA C N S 138 |
| HIS C C N N 139 |
| HIS O O N N 140 |
| HIS CB C N N 141 |
| HIS CG C Y N 142 |
| HIS ND1 N Y N 143 |
| HIS CD2 C Y N 144 |
| HIS CE1 C Y N 145 |
| HIS NE2 N Y N 146 |
| HIS OXT O N N 147 |
| HIS H H N N 148 |
| HIS H2 H N N 149 |
| HIS HA H N N 150 |
| HIS HB2 H N N 151 |
| HIS HB3 H N N 152 |
| HIS HD1 H N N 153 |
| HIS HD2 H N N 154 |
| HIS HE1 H N N 155 |
| HIS HE2 H N N 156 |
| HIS HXT H N N 157 |
| HOH O O N N 158 |
| HOH H1 H N N 159 |
| HOH H2 H N N 160 |
| ILE N N N N 161 |
| ILE CA C N S 162 |
| ILE C C N N 163 |
| ILE O O N N 164 |
| ILE CB C N S 165 |
| ILE CG1 C N N 166 |
| ILE CG2 C N N 167 |
| ILE CD1 C N N 168 |
| ILE OXT O N N 169 |
| ILE H H N N 170 |
| ILE H2 H N N 171 |
| ILE HA H N N 172 |
| ILE HB H N N 173 |
| ILE HG12 H N N 174 |
| ILE HG13 H N N 175 |
| ILE HG21 H N N 176 |
| ILE HG22 H N N 177 |
| ILE HG23 H N N 178 |
| ILE HD11 H N N 179 |
| ILE HD12 H N N 180 |
| ILE HD13 H N N 181 |
| ILE HXT H N N 182 |
| LEU N N N N 183 |
| LEU CA C N S 184 |
| LEU C C N N 185 |
| LEU O O N N 186 |
| LEU CB C N N 187 |
| LEU CG C N N 188 |
| LEU CD1 C N N 189 |
| LEU CD2 C N N 190 |
| LEU OXT O N N 191 |
| LEU H H N N 192 |
| LEU H2 H N N 193 |
| LEU HA H N N 194 |
| LEU HB2 H N N 195 |
| LEU HB3 H N N 196 |
| LEU HG H N N 197 |
| LEU HD11 H N N 198 |
| LEU HD12 H N N 199 |
| LEU HD13 H N N 200 |
| LEU HD21 H N N 201 |
| LEU HD22 H N N 202 |
| LEU HD23 H N N 203 |
| LEU HXT H N N 204 |
| LYS N N N N 205 |
| LYS CA C N S 206 |
| LYS C C N N 207 |
| LYS O O N N 208 |
| LYS CB C N N 209 |
| LYS CG C N N 210 |
| LYS CD C N N 211 |
| LYS CE C N N 212 |
| LYS NZ N N N 213 |
| LYS OXT O N N 214 |
| LYS H H N N 215 |
| LYS H2 H N N 216 |
| LYS HA H N N 217 |
| LYS HB2 H N N 218 |
| LYS HB3 H N N 219 |
| LYS HG2 H N N 220 |
| LYS HG3 H N N 221 |
| LYS HD2 H N N 222 |
| LYS HD3 H N N 223 |
| LYS HE2 H N N 224 |
| LYS HE3 H N N 225 |
| LYS HZ1 H N N 226 |
| LYS HZ2 H N N 227 |
| LYS HZ3 H N N 228 |
| LYS HXT H N N 229 |
| MET N N N N 230 |
| MET CA C N S 231 |
| MET C C N N 232 |
| MET O O N N 233 |
| MET CB C N N 234 |
| MET CG C N N 235 |
| MET SD S N N 236 |
| MET CE C N N 237 |
| MET OXT O N N 238 |
| MET H H N N 239 |
| MET H2 H N N 240 |
| MET HA H N N 241 |
| MET HB2 H N N 242 |
| MET HB3 H N N 243 |
| MET HG2 H N N 244 |
| MET HG3 H N N 245 |
| MET HE1 H N N 246 |
| MET HE2 H N N 247 |
| MET HE3 H N N 248 |
| MET HXT H N N 249 |
| PHE N N N N 250 |
| PHE CA C N S 251 |
| PHE C C N N 252 |
| PHE O O N N 253 |
| PHE CB C N N 254 |
| PHE CG C Y N 255 |
| PHE CD1 C Y N 256 |
| PHE CD2 C Y N 257 |
| PHE CE1 C Y N 258 |
| PHE CE2 C Y N 259 |
| PHE CZ C Y N 260 |
| PHE OXT O N N 261 |
| PHE H H N N 262 |
| PHE H2 H N N 263 |
| PHE HA H N N 264 |
| PHE HB2 H N N 265 |
| PHE HB3 H N N 266 |
| PHE HD1 H N N 267 |
| PHE HD2 H N N 268 |
| PHE HE1 H N N 269 |
| PHE HE2 H N N 270 |
| PHE HZ H N N 271 |
| PHE HXT H N N 272 |
| PRO N N N N 273 |
| PRO CA C N S 274 |
| PRO C C N N 275 |
| PRO O O N N 276 |
| PRO CB C N N 277 |
| PRO CG C N N 278 |
| PRO CD C N N 279 |
| PRO OXT O N N 280 |
| PRO H H N N 281 |
| PRO HA H N N 282 |
| PRO HB2 H N N 283 |
| PRO HB3 H N N 284 |
| PRO HG2 H N N 285 |
| PRO HG3 H N N 286 |
| PRO HD2 H N N 287 |
| PRO HD3 H N N 288 |
| PRO HXT H N N 289 |
| SER N N N N 290 |
| SER CA C N S 291 |
| SER C C N N 292 |
| SER O O N N 293 |
| SER CB C N N 294 |
| SER OG O N N 295 |
| SER OXT O N N 296 |
| SER H H N N 297 |
| SER H2 H N N 298 |
| SER HA H N N 299 |
| SER HB2 H N N 300 |
| SER HB3 H N N 301 |
| SER HG H N N 302 |
| SER HXT H N N 303 |
| THR N N N N 304 |
| THR CA C N S 305 |
| THR C C N N 306 |
| THR O O N N 307 |
| THR CB C N R 308 |
| THR OG1 O N N 309 |
| THR CG2 C N N 310 |
| THR OXT O N N 311 |
| THR H H N N 312 |
| THR H2 H N N 313 |
| THR HA H N N 314 |
| THR HB H N N 315 |
| THR HG1 H N N 316 |
| THR HG21 H N N 317 |
| THR HG22 H N N 318 |
| THR HG23 H N N 319 |
| THR HXT H N N 320 |
| TRP N N N N 321 |
| TRP CA C N S 322 |
| TRP C C N N 323 |
| TRP O O N N 324 |
| TRP CB C N N 325 |
| TRP CG C Y N 326 |
| TRP CD1 C Y N 327 |
| TRP CD2 C Y N 328 |
| TRP NE1 N Y N 329 |
| TRP CE2 C Y N 330 |
| TRP CE3 C Y N 331 |
| TRP CZ2 C Y N 332 |
| TRP CZ3 C Y N 333 |
| TRP CH2 C Y N 334 |
| TRP OXT O N N 335 |
| TRP H H N N 336 |
| TRP H2 H N N 337 |
| TRP HA H N N 338 |
| TRP HB2 H N N 339 |
| TRP HB3 H N N 340 |
| TRP HD1 H N N 341 |
| TRP HE1 H N N 342 |
| TRP HE3 H N N 343 |
| TRP HZ2 H N N 344 |
| TRP HZ3 H N N 345 |
| TRP HH2 H N N 346 |
| TRP HXT H N N 347 |
| TYR N N N N 348 |
| TYR CA C N S 349 |
| TYR C C N N 350 |
| TYR O O N N 351 |
| TYR CB C N N 352 |
| TYR CG C Y N 353 |
| TYR CD1 C Y N 354 |
| TYR CD2 C Y N 355 |
| TYR CE1 C Y N 356 |
| TYR CE2 C Y N 357 |
| TYR CZ C Y N 358 |
| TYR OH O N N 359 |
| TYR OXT O N N 360 |
| TYR H H N N 361 |
| TYR H2 H N N 362 |
| TYR HA H N N 363 |
| TYR HB2 H N N 364 |
| TYR HB3 H N N 365 |
| TYR HD1 H N N 366 |
| TYR HD2 H N N 367 |
| TYR HE1 H N N 368 |
| TYR HE2 H N N 369 |
| TYR HH H N N 370 |
| TYR HXT H N N 371 |
| VAL N N N N 372 |
| VAL CA C N S 373 |
| VAL C C N N 374 |
| VAL O O N N 375 |
| VAL CB C N N 376 |
| VAL CG1 C N N 377 |
| VAL CG2 C N N 378 |
| VAL OXT O N N 379 |
| VAL H H N N 380 |
| VAL H2 H N N 381 |
| VAL HA H N N 382 |
| VAL HB H N N 383 |
| VAL HG11 H N N 384 |
| VAL HG12 H N N 385 |
| VAL HG13 H N N 386 |
| VAL HG21 H N N 387 |
| VAL HG22 H N N 388 |
| VAL HG23 H N N 389 |
| VAL HXT H N N 390 |
| |
| loop_ |
| _chem_comp_bond.comp_id |
| _chem_comp_bond.atom_id_1 |
| _chem_comp_bond.atom_id_2 |
| _chem_comp_bond.value_order |
| _chem_comp_bond.pdbx_aromatic_flag |
| _chem_comp_bond.pdbx_stereo_config |
| _chem_comp_bond.pdbx_ordinal |
| ALA N CA sing N N 1 |
| ALA N H sing N N 2 |
| ALA N H2 sing N N 3 |
| ALA CA C sing N N 4 |
| ALA CA CB sing N N 5 |
| ALA CA HA sing N N 6 |
| ALA C O doub N N 7 |
| ALA C OXT sing N N 8 |
| ALA CB HB1 sing N N 9 |
| ALA CB HB2 sing N N 10 |
| ALA CB HB3 sing N N 11 |
| ALA OXT HXT sing N N 12 |
| ARG N CA sing N N 13 |
| ARG N H sing N N 14 |
| ARG N H2 sing N N 15 |
| ARG CA C sing N N 16 |
| ARG CA CB sing N N 17 |
| ARG CA HA sing N N 18 |
| ARG C O doub N N 19 |
| ARG C OXT sing N N 20 |
| ARG CB CG sing N N 21 |
| ARG CB HB2 sing N N 22 |
| ARG CB HB3 sing N N 23 |
| ARG CG CD sing N N 24 |
| ARG CG HG2 sing N N 25 |
| ARG CG HG3 sing N N 26 |
| ARG CD NE sing N N 27 |
| ARG CD HD2 sing N N 28 |
| ARG CD HD3 sing N N 29 |
| ARG NE CZ sing N N 30 |
| ARG NE HE sing N N 31 |
| ARG CZ NH1 sing N N 32 |
| ARG CZ NH2 doub N N 33 |
| ARG NH1 HH11 sing N N 34 |
| ARG NH1 HH12 sing N N 35 |
| ARG NH2 HH21 sing N N 36 |
| ARG NH2 HH22 sing N N 37 |
| ARG OXT HXT sing N N 38 |
| ASN N CA sing N N 39 |
| ASN N H sing N N 40 |
| ASN N H2 sing N N 41 |
| ASN CA C sing N N 42 |
| ASN CA CB sing N N 43 |
| ASN CA HA sing N N 44 |
| ASN C O doub N N 45 |
| ASN C OXT sing N N 46 |
| ASN CB CG sing N N 47 |
| ASN CB HB2 sing N N 48 |
| ASN CB HB3 sing N N 49 |
| ASN CG OD1 doub N N 50 |
| ASN CG ND2 sing N N 51 |
| ASN ND2 HD21 sing N N 52 |
| ASN ND2 HD22 sing N N 53 |
| ASN OXT HXT sing N N 54 |
| ASP N CA sing N N 55 |
| ASP N H sing N N 56 |
| ASP N H2 sing N N 57 |
| ASP CA C sing N N 58 |
| ASP CA CB sing N N 59 |
| ASP CA HA sing N N 60 |
| ASP C O doub N N 61 |
| ASP C OXT sing N N 62 |
| ASP CB CG sing N N 63 |
| ASP CB HB2 sing N N 64 |
| ASP CB HB3 sing N N 65 |
| ASP CG OD1 doub N N 66 |
| ASP CG OD2 sing N N 67 |
| ASP OD2 HD2 sing N N 68 |
| ASP OXT HXT sing N N 69 |
| CYS N CA sing N N 70 |
| CYS N H sing N N 71 |
| CYS N H2 sing N N 72 |
| CYS CA C sing N N 73 |
| CYS CA CB sing N N 74 |
| CYS CA HA sing N N 75 |
| CYS C O doub N N 76 |
| CYS C OXT sing N N 77 |
| CYS CB SG sing N N 78 |
| CYS CB HB2 sing N N 79 |
| CYS CB HB3 sing N N 80 |
| CYS SG HG sing N N 81 |
| CYS OXT HXT sing N N 82 |
| GLN N CA sing N N 83 |
| GLN N H sing N N 84 |
| GLN N H2 sing N N 85 |
| GLN CA C sing N N 86 |
| GLN CA CB sing N N 87 |
| GLN CA HA sing N N 88 |
| GLN C O doub N N 89 |
| GLN C OXT sing N N 90 |
| GLN CB CG sing N N 91 |
| GLN CB HB2 sing N N 92 |
| GLN CB HB3 sing N N 93 |
| GLN CG CD sing N N 94 |
| GLN CG HG2 sing N N 95 |
| GLN CG HG3 sing N N 96 |
| GLN CD OE1 doub N N 97 |
| GLN CD NE2 sing N N 98 |
| GLN NE2 HE21 sing N N 99 |
| GLN NE2 HE22 sing N N 100 |
| GLN OXT HXT sing N N 101 |
| GLU N CA sing N N 102 |
| GLU N H sing N N 103 |
| GLU N H2 sing N N 104 |
| GLU CA C sing N N 105 |
| GLU CA CB sing N N 106 |
| GLU CA HA sing N N 107 |
| GLU C O doub N N 108 |
| GLU C OXT sing N N 109 |
| GLU CB CG sing N N 110 |
| GLU CB HB2 sing N N 111 |
| GLU CB HB3 sing N N 112 |
| GLU CG CD sing N N 113 |
| GLU CG HG2 sing N N 114 |
| GLU CG HG3 sing N N 115 |
| GLU CD OE1 doub N N 116 |
| GLU CD OE2 sing N N 117 |
| GLU OE2 HE2 sing N N 118 |
| GLU OXT HXT sing N N 119 |
| GLY N CA sing N N 120 |
| GLY N H sing N N 121 |
| GLY N H2 sing N N 122 |
| GLY CA C sing N N 123 |
| GLY CA HA2 sing N N 124 |
| GLY CA HA3 sing N N 125 |
| GLY C O doub N N 126 |
| GLY C OXT sing N N 127 |
| GLY OXT HXT sing N N 128 |
| HIS N CA sing N N 129 |
| HIS N H sing N N 130 |
| HIS N H2 sing N N 131 |
| HIS CA C sing N N 132 |
| HIS CA CB sing N N 133 |
| HIS CA HA sing N N 134 |
| HIS C O doub N N 135 |
| HIS C OXT sing N N 136 |
| HIS CB CG sing N N 137 |
| HIS CB HB2 sing N N 138 |
| HIS CB HB3 sing N N 139 |
| HIS CG ND1 sing Y N 140 |
| HIS CG CD2 doub Y N 141 |
| HIS ND1 CE1 doub Y N 142 |
| HIS ND1 HD1 sing N N 143 |
| HIS CD2 NE2 sing Y N 144 |
| HIS CD2 HD2 sing N N 145 |
| HIS CE1 NE2 sing Y N 146 |
| HIS CE1 HE1 sing N N 147 |
| HIS NE2 HE2 sing N N 148 |
| HIS OXT HXT sing N N 149 |
| HOH O H1 sing N N 150 |
| HOH O H2 sing N N 151 |
| ILE N CA sing N N 152 |
| ILE N H sing N N 153 |
| ILE N H2 sing N N 154 |
| ILE CA C sing N N 155 |
| ILE CA CB sing N N 156 |
| ILE CA HA sing N N 157 |
| ILE C O doub N N 158 |
| ILE C OXT sing N N 159 |
| ILE CB CG1 sing N N 160 |
| ILE CB CG2 sing N N 161 |
| ILE CB HB sing N N 162 |
| ILE CG1 CD1 sing N N 163 |
| ILE CG1 HG12 sing N N 164 |
| ILE CG1 HG13 sing N N 165 |
| ILE CG2 HG21 sing N N 166 |
| ILE CG2 HG22 sing N N 167 |
| ILE CG2 HG23 sing N N 168 |
| ILE CD1 HD11 sing N N 169 |
| ILE CD1 HD12 sing N N 170 |
| ILE CD1 HD13 sing N N 171 |
| ILE OXT HXT sing N N 172 |
| LEU N CA sing N N 173 |
| LEU N H sing N N 174 |
| LEU N H2 sing N N 175 |
| LEU CA C sing N N 176 |
| LEU CA CB sing N N 177 |
| LEU CA HA sing N N 178 |
| LEU C O doub N N 179 |
| LEU C OXT sing N N 180 |
| LEU CB CG sing N N 181 |
| LEU CB HB2 sing N N 182 |
| LEU CB HB3 sing N N 183 |
| LEU CG CD1 sing N N 184 |
| LEU CG CD2 sing N N 185 |
| LEU CG HG sing N N 186 |
| LEU CD1 HD11 sing N N 187 |
| LEU CD1 HD12 sing N N 188 |
| LEU CD1 HD13 sing N N 189 |
| LEU CD2 HD21 sing N N 190 |
| LEU CD2 HD22 sing N N 191 |
| LEU CD2 HD23 sing N N 192 |
| LEU OXT HXT sing N N 193 |
| LYS N CA sing N N 194 |
| LYS N H sing N N 195 |
| LYS N H2 sing N N 196 |
| LYS CA C sing N N 197 |
| LYS CA CB sing N N 198 |
| LYS CA HA sing N N 199 |
| LYS C O doub N N 200 |
| LYS C OXT sing N N 201 |
| LYS CB CG sing N N 202 |
| LYS CB HB2 sing N N 203 |
| LYS CB HB3 sing N N 204 |
| LYS CG CD sing N N 205 |
| LYS CG HG2 sing N N 206 |
| LYS CG HG3 sing N N 207 |
| LYS CD CE sing N N 208 |
| LYS CD HD2 sing N N 209 |
| LYS CD HD3 sing N N 210 |
| LYS CE NZ sing N N 211 |
| LYS CE HE2 sing N N 212 |
| LYS CE HE3 sing N N 213 |
| LYS NZ HZ1 sing N N 214 |
| LYS NZ HZ2 sing N N 215 |
| LYS NZ HZ3 sing N N 216 |
| LYS OXT HXT sing N N 217 |
| MET N CA sing N N 218 |
| MET N H sing N N 219 |
| MET N H2 sing N N 220 |
| MET CA C sing N N 221 |
| MET CA CB sing N N 222 |
| MET CA HA sing N N 223 |
| MET C O doub N N 224 |
| MET C OXT sing N N 225 |
| MET CB CG sing N N 226 |
| MET CB HB2 sing N N 227 |
| MET CB HB3 sing N N 228 |
| MET CG SD sing N N 229 |
| MET CG HG2 sing N N 230 |
| MET CG HG3 sing N N 231 |
| MET SD CE sing N N 232 |
| MET CE HE1 sing N N 233 |
| MET CE HE2 sing N N 234 |
| MET CE HE3 sing N N 235 |
| MET OXT HXT sing N N 236 |
| PHE N CA sing N N 237 |
| PHE N H sing N N 238 |
| PHE N H2 sing N N 239 |
| PHE CA C sing N N 240 |
| PHE CA CB sing N N 241 |
| PHE CA HA sing N N 242 |
| PHE C O doub N N 243 |
| PHE C OXT sing N N 244 |
| PHE CB CG sing N N 245 |
| PHE CB HB2 sing N N 246 |
| PHE CB HB3 sing N N 247 |
| PHE CG CD1 doub Y N 248 |
| PHE CG CD2 sing Y N 249 |
| PHE CD1 CE1 sing Y N 250 |
| PHE CD1 HD1 sing N N 251 |
| PHE CD2 CE2 doub Y N 252 |
| PHE CD2 HD2 sing N N 253 |
| PHE CE1 CZ doub Y N 254 |
| PHE CE1 HE1 sing N N 255 |
| PHE CE2 CZ sing Y N 256 |
| PHE CE2 HE2 sing N N 257 |
| PHE CZ HZ sing N N 258 |
| PHE OXT HXT sing N N 259 |
| PRO N CA sing N N 260 |
| PRO N CD sing N N 261 |
| PRO N H sing N N 262 |
| PRO CA C sing N N 263 |
| PRO CA CB sing N N 264 |
| PRO CA HA sing N N 265 |
| PRO C O doub N N 266 |
| PRO C OXT sing N N 267 |
| PRO CB CG sing N N 268 |
| PRO CB HB2 sing N N 269 |
| PRO CB HB3 sing N N 270 |
| PRO CG CD sing N N 271 |
| PRO CG HG2 sing N N 272 |
| PRO CG HG3 sing N N 273 |
| PRO CD HD2 sing N N 274 |
| PRO CD HD3 sing N N 275 |
| PRO OXT HXT sing N N 276 |
| SER N CA sing N N 277 |
| SER N H sing N N 278 |
| SER N H2 sing N N 279 |
| SER CA C sing N N 280 |
| SER CA CB sing N N 281 |
| SER CA HA sing N N 282 |
| SER C O doub N N 283 |
| SER C OXT sing N N 284 |
| SER CB OG sing N N 285 |
| SER CB HB2 sing N N 286 |
| SER CB HB3 sing N N 287 |
| SER OG HG sing N N 288 |
| SER OXT HXT sing N N 289 |
| THR N CA sing N N 290 |
| THR N H sing N N 291 |
| THR N H2 sing N N 292 |
| THR CA C sing N N 293 |
| THR CA CB sing N N 294 |
| THR CA HA sing N N 295 |
| THR C O doub N N 296 |
| THR C OXT sing N N 297 |
| THR CB OG1 sing N N 298 |
| THR CB CG2 sing N N 299 |
| THR CB HB sing N N 300 |
| THR OG1 HG1 sing N N 301 |
| THR CG2 HG21 sing N N 302 |
| THR CG2 HG22 sing N N 303 |
| THR CG2 HG23 sing N N 304 |
| THR OXT HXT sing N N 305 |
| TRP N CA sing N N 306 |
| TRP N H sing N N 307 |
| TRP N H2 sing N N 308 |
| TRP CA C sing N N 309 |
| TRP CA CB sing N N 310 |
| TRP CA HA sing N N 311 |
| TRP C O doub N N 312 |
| TRP C OXT sing N N 313 |
| TRP CB CG sing N N 314 |
| TRP CB HB2 sing N N 315 |
| TRP CB HB3 sing N N 316 |
| TRP CG CD1 doub Y N 317 |
| TRP CG CD2 sing Y N 318 |
| TRP CD1 NE1 sing Y N 319 |
| TRP CD1 HD1 sing N N 320 |
| TRP CD2 CE2 doub Y N 321 |
| TRP CD2 CE3 sing Y N 322 |
| TRP NE1 CE2 sing Y N 323 |
| TRP NE1 HE1 sing N N 324 |
| TRP CE2 CZ2 sing Y N 325 |
| TRP CE3 CZ3 doub Y N 326 |
| TRP CE3 HE3 sing N N 327 |
| TRP CZ2 CH2 doub Y N 328 |
| TRP CZ2 HZ2 sing N N 329 |
| TRP CZ3 CH2 sing Y N 330 |
| TRP CZ3 HZ3 sing N N 331 |
| TRP CH2 HH2 sing N N 332 |
| TRP OXT HXT sing N N 333 |
| TYR N CA sing N N 334 |
| TYR N H sing N N 335 |
| TYR N H2 sing N N 336 |
| TYR CA C sing N N 337 |
| TYR CA CB sing N N 338 |
| TYR CA HA sing N N 339 |
| TYR C O doub N N 340 |
| TYR C OXT sing N N 341 |
| TYR CB CG sing N N 342 |
| TYR CB HB2 sing N N 343 |
| TYR CB HB3 sing N N 344 |
| TYR CG CD1 doub Y N 345 |
| TYR CG CD2 sing Y N 346 |
| TYR CD1 CE1 sing Y N 347 |
| TYR CD1 HD1 sing N N 348 |
| TYR CD2 CE2 doub Y N 349 |
| TYR CD2 HD2 sing N N 350 |
| TYR CE1 CZ doub Y N 351 |
| TYR CE1 HE1 sing N N 352 |
| TYR CE2 CZ sing Y N 353 |
| TYR CE2 HE2 sing N N 354 |
| TYR CZ OH sing N N 355 |
| TYR OH HH sing N N 356 |
| TYR OXT HXT sing N N 357 |
| VAL N CA sing N N 358 |
| VAL N H sing N N 359 |
| VAL N H2 sing N N 360 |
| VAL CA C sing N N 361 |
| VAL CA CB sing N N 362 |
| VAL CA HA sing N N 363 |
| VAL C O doub N N 364 |
| VAL C OXT sing N N 365 |
| VAL CB CG1 sing N N 366 |
| VAL CB CG2 sing N N 367 |
| VAL CB HB sing N N 368 |
| VAL CG1 HG11 sing N N 369 |
| VAL CG1 HG12 sing N N 370 |
| VAL CG1 HG13 sing N N 371 |
| VAL CG2 HG21 sing N N 372 |
| VAL CG2 HG22 sing N N 373 |
| VAL CG2 HG23 sing N N 374 |
| VAL OXT HXT sing N N 375 |
| |
| _pdbx_initial_refinement_model.id 1 |
| _pdbx_initial_refinement_model.entity_id_list ? |
| _pdbx_initial_refinement_model.type 'experimental model' |
| _pdbx_initial_refinement_model.source_name PDB |
| _pdbx_initial_refinement_model.accession_code 1U6D |
| _pdbx_initial_refinement_model.details ? |
| |
| _atom_sites.entry_id 2FLU |
| _atom_sites.fract_transf_matrix[1][1] 0.013028 |
| _atom_sites.fract_transf_matrix[1][2] 0.000000 |
| _atom_sites.fract_transf_matrix[1][3] 0.000000 |
| _atom_sites.fract_transf_matrix[2][1] 0.000000 |
| _atom_sites.fract_transf_matrix[2][2] 0.010861 |
| _atom_sites.fract_transf_matrix[2][3] 0.000000 |
| _atom_sites.fract_transf_matrix[3][1] 0.000000 |
| _atom_sites.fract_transf_matrix[3][2] 0.000000 |
| _atom_sites.fract_transf_matrix[3][3] 0.021592 |
| _atom_sites.fract_transf_vector[1] 0.00000 |
| _atom_sites.fract_transf_vector[2] 0.00000 |
| _atom_sites.fract_transf_vector[3] 0.00000 |
| |
| loop_ |
| _atom_type.symbol |
| C |
| N |
| O |
| S |
| |
| loop_ |
| _atom_site.group_PDB |
| _atom_site.id |
| _atom_site.type_symbol |
| _atom_site.label_atom_id |
| _atom_site.label_alt_id |
| _atom_site.label_comp_id |
| _atom_site.label_asym_id |
| _atom_site.label_entity_id |
| _atom_site.label_seq_id |
| _atom_site.pdbx_PDB_ins_code |
| _atom_site.Cartn_x |
| _atom_site.Cartn_y |
| _atom_site.Cartn_z |
| _atom_site.occupancy |
| _atom_site.B_iso_or_equiv |
| _atom_site.pdbx_formal_charge |
| _atom_site.auth_seq_id |
| _atom_site.auth_comp_id |
| _atom_site.auth_asym_id |
| _atom_site.auth_atom_id |
| _atom_site.pdbx_PDB_model_num |
| ATOM 1 N N . GLY A 1 24 ? 34.879 9.859 20.779 1.00 24.76 ? 325 GLY X N 1 |
| ATOM 2 C CA . GLY A 1 24 ? 34.589 11.247 20.302 1.00 23.21 ? 325 GLY X CA 1 |
| ATOM 3 C C . GLY A 1 24 ? 33.110 11.473 20.040 1.00 22.66 ? 325 GLY X C 1 |
| ATOM 4 O O . GLY A 1 24 ? 32.246 10.903 20.728 1.00 23.30 ? 325 GLY X O 1 |
| ATOM 5 N N A ARG A 1 25 ? 32.814 12.310 19.048 0.50 21.79 ? 326 ARG X N 1 |
| ATOM 6 N N B ARG A 1 25 ? 32.817 12.302 19.042 0.50 21.76 ? 326 ARG X N 1 |
| ATOM 7 C CA A ARG A 1 25 ? 31.427 12.623 18.694 0.50 20.66 ? 326 ARG X CA 1 |
| ATOM 8 C CA B ARG A 1 25 ? 31.434 12.622 18.678 0.50 20.62 ? 326 ARG X CA 1 |
| ATOM 9 C C A ARG A 1 25 ? 30.724 11.424 18.060 0.50 19.76 ? 326 ARG X C 1 |
| ATOM 10 C C B ARG A 1 25 ? 30.724 11.423 18.053 0.50 19.74 ? 326 ARG X C 1 |
| ATOM 11 O O A ARG A 1 25 ? 31.356 10.592 17.405 0.50 19.37 ? 326 ARG X O 1 |
| ATOM 12 O O B ARG A 1 25 ? 31.351 10.587 17.398 0.50 19.35 ? 326 ARG X O 1 |
| ATOM 13 C CB A ARG A 1 25 ? 31.345 13.848 17.775 0.50 21.03 ? 326 ARG X CB 1 |
| ATOM 14 C CB B ARG A 1 25 ? 31.379 13.835 17.744 0.50 20.96 ? 326 ARG X CB 1 |
| ATOM 15 C CG A ARG A 1 25 ? 32.017 15.098 18.350 0.50 21.84 ? 326 ARG X CG 1 |
| ATOM 16 C CG B ARG A 1 25 ? 32.087 15.066 18.308 0.50 21.67 ? 326 ARG X CG 1 |
| ATOM 17 C CD A ARG A 1 25 ? 31.259 16.380 18.014 0.50 23.79 ? 326 ARG X CD 1 |
| ATOM 18 C CD B ARG A 1 25 ? 31.598 16.367 17.680 0.50 23.20 ? 326 ARG X CD 1 |
| ATOM 19 N NE A ARG A 1 25 ? 31.299 16.720 16.593 0.50 25.03 ? 326 ARG X NE 1 |
| ATOM 20 N NE B ARG A 1 25 ? 32.191 17.540 18.328 0.50 24.71 ? 326 ARG X NE 1 |
| ATOM 21 C CZ A ARG A 1 25 ? 30.557 17.671 16.027 0.50 25.91 ? 326 ARG X CZ 1 |
| ATOM 22 C CZ B ARG A 1 25 ? 31.773 18.076 19.478 0.50 25.62 ? 326 ARG X CZ 1 |
| ATOM 23 N NH1 A ARG A 1 25 ? 29.706 18.389 16.754 0.50 26.83 ? 326 ARG X NH1 1 |
| ATOM 24 N NH1 B ARG A 1 25 ? 32.393 19.142 19.967 0.50 26.14 ? 326 ARG X NH1 1 |
| ATOM 25 N NH2 A ARG A 1 25 ? 30.658 17.905 14.727 0.50 25.08 ? 326 ARG X NH2 1 |
| ATOM 26 N NH2 B ARG A 1 25 ? 30.744 17.560 20.147 0.50 24.73 ? 326 ARG X NH2 1 |
| ATOM 27 N N . LEU A 1 26 ? 29.414 11.344 18.280 1.00 18.58 ? 327 LEU X N 1 |
| ATOM 28 C CA . LEU A 1 26 ? 28.604 10.237 17.790 1.00 17.27 ? 327 LEU X CA 1 |
| ATOM 29 C C . LEU A 1 26 ? 27.592 10.760 16.783 1.00 16.81 ? 327 LEU X C 1 |
| ATOM 30 O O . LEU A 1 26 ? 27.237 11.947 16.808 1.00 16.59 ? 327 LEU X O 1 |
| ATOM 31 C CB . LEU A 1 26 ? 27.861 9.559 18.943 1.00 17.00 ? 327 LEU X CB 1 |
| ATOM 32 C CG . LEU A 1 26 ? 28.729 9.012 20.081 1.00 17.29 ? 327 LEU X CG 1 |
| ATOM 33 C CD1 . LEU A 1 26 ? 27.846 8.518 21.201 1.00 18.49 ? 327 LEU X CD1 1 |
| ATOM 34 C CD2 . LEU A 1 26 ? 29.646 7.899 19.589 1.00 17.43 ? 327 LEU X CD2 1 |
| ATOM 35 N N . ILE A 1 27 ? 27.148 9.868 15.900 1.00 15.88 ? 328 ILE X N 1 |
| ATOM 36 C CA . ILE A 1 27 ? 26.047 10.141 14.984 1.00 16.19 ? 328 ILE X CA 1 |
| ATOM 37 C C . ILE A 1 27 ? 24.772 9.615 15.629 1.00 15.96 ? 328 ILE X C 1 |
| ATOM 38 O O . ILE A 1 27 ? 24.632 8.415 15.850 1.00 15.89 ? 328 ILE X O 1 |
| ATOM 39 C CB . ILE A 1 27 ? 26.272 9.423 13.634 1.00 15.96 ? 328 ILE X CB 1 |
| ATOM 40 C CG1 . ILE A 1 27 ? 27.504 9.996 12.922 1.00 16.51 ? 328 ILE X CG1 1 |
| ATOM 41 C CG2 . ILE A 1 27 ? 25.041 9.562 12.725 1.00 16.30 ? 328 ILE X CG2 1 |
| ATOM 42 C CD1 . ILE A 1 27 ? 27.904 9.206 11.684 1.00 17.70 ? 328 ILE X CD1 1 |
| ATOM 43 N N . TYR A 1 28 ? 23.852 10.530 15.926 1.00 15.72 ? 329 TYR X N 1 |
| ATOM 44 C CA . TYR A 1 28 ? 22.559 10.188 16.508 1.00 16.07 ? 329 TYR X CA 1 |
| ATOM 45 C C . TYR A 1 28 ? 21.501 10.136 15.439 1.00 15.81 ? 329 TYR X C 1 |
| ATOM 46 O O . TYR A 1 28 ? 21.398 11.062 14.630 1.00 16.93 ? 329 TYR X O 1 |
| ATOM 47 C CB . TYR A 1 28 ? 22.150 11.242 17.528 1.00 16.03 ? 329 TYR X CB 1 |
| ATOM 48 C CG . TYR A 1 28 ? 23.032 11.260 18.748 1.00 15.52 ? 329 TYR X CG 1 |
| ATOM 49 C CD1 . TYR A 1 28 ? 24.224 11.990 18.759 1.00 15.82 ? 329 TYR X CD1 1 |
| ATOM 50 C CD2 . TYR A 1 28 ? 22.676 10.551 19.898 1.00 16.00 ? 329 TYR X CD2 1 |
| ATOM 51 C CE1 . TYR A 1 28 ? 25.054 12.004 19.891 1.00 15.81 ? 329 TYR X CE1 1 |
| ATOM 52 C CE2 . TYR A 1 28 ? 23.488 10.564 21.026 1.00 16.46 ? 329 TYR X CE2 1 |
| ATOM 53 C CZ . TYR A 1 28 ? 24.669 11.289 21.020 1.00 16.54 ? 329 TYR X CZ 1 |
| ATOM 54 O OH . TYR A 1 28 ? 25.481 11.304 22.131 1.00 17.27 ? 329 TYR X OH 1 |
| ATOM 55 N N . THR A 1 29 ? 20.704 9.074 15.455 1.00 15.48 ? 330 THR X N 1 |
| ATOM 56 C CA . THR A 1 29 ? 19.528 9.011 14.592 1.00 15.53 ? 330 THR X CA 1 |
| ATOM 57 C C . THR A 1 29 ? 18.264 8.787 15.418 1.00 15.04 ? 330 THR X C 1 |
| ATOM 58 O O . THR A 1 29 ? 18.225 7.907 16.288 1.00 15.34 ? 330 THR X O 1 |
| ATOM 59 C CB . THR A 1 29 ? 19.674 7.939 13.501 1.00 16.89 ? 330 THR X CB 1 |
| ATOM 60 O OG1 . THR A 1 29 ? 18.490 7.935 12.691 1.00 18.86 ? 330 THR X OG1 1 |
| ATOM 61 C CG2 . THR A 1 29 ? 19.897 6.552 14.108 1.00 17.52 ? 330 THR X CG2 1 |
| ATOM 62 N N . ALA A 1 30 ? 17.251 9.608 15.143 1.00 14.33 ? 331 ALA X N 1 |
| ATOM 63 C CA . ALA A 1 30 ? 16.026 9.644 15.923 1.00 14.18 ? 331 ALA X CA 1 |
| ATOM 64 C C . ALA A 1 30 ? 14.831 9.402 15.010 1.00 14.37 ? 331 ALA X C 1 |
| ATOM 65 O O . ALA A 1 30 ? 14.764 9.970 13.934 1.00 14.42 ? 331 ALA X O 1 |
| ATOM 66 C CB . ALA A 1 30 ? 15.890 10.999 16.631 1.00 15.28 ? 331 ALA X CB 1 |
| ATOM 67 N N . GLY A 1 31 ? 13.914 8.541 15.437 1.00 13.82 ? 332 GLY X N 1 |
| ATOM 68 C CA . GLY A 1 31 ? 12.658 8.350 14.716 1.00 13.20 ? 332 GLY X CA 1 |
| ATOM 69 C C . GLY A 1 31 ? 12.828 7.632 13.393 1.00 13.46 ? 332 GLY X C 1 |
| ATOM 70 O O . GLY A 1 31 ? 13.757 6.844 13.212 1.00 14.59 ? 332 GLY X O 1 |
| ATOM 71 N N . GLY A 1 32 ? 11.909 7.916 12.476 1.00 12.83 ? 333 GLY X N 1 |
| ATOM 72 C CA . GLY A 1 32 ? 11.901 7.273 11.167 1.00 12.25 ? 333 GLY X CA 1 |
| ATOM 73 C C . GLY A 1 32 ? 10.634 6.455 11.026 1.00 12.84 ? 333 GLY X C 1 |
| ATOM 74 O O . GLY A 1 32 ? 9.755 6.489 11.910 1.00 13.54 ? 333 GLY X O 1 |
| ATOM 75 N N . TYR A 1 33 ? 10.528 5.735 9.913 1.00 12.38 ? 334 TYR X N 1 |
| ATOM 76 C CA . TYR A 1 33 ? 9.338 4.986 9.607 1.00 13.24 ? 334 TYR X CA 1 |
| ATOM 77 C C . TYR A 1 33 ? 9.659 3.626 9.037 1.00 13.28 ? 334 TYR X C 1 |
| ATOM 78 O O . TYR A 1 33 ? 10.480 3.508 8.150 1.00 12.44 ? 334 TYR X O 1 |
| ATOM 79 C CB . TYR A 1 33 ? 8.533 5.756 8.578 1.00 12.94 ? 334 TYR X CB 1 |
| ATOM 80 C CG . TYR A 1 33 ? 7.195 5.149 8.198 1.00 13.88 ? 334 TYR X CG 1 |
| ATOM 81 C CD1 . TYR A 1 33 ? 7.100 4.202 7.188 1.00 13.58 ? 334 TYR X CD1 1 |
| ATOM 82 C CD2 . TYR A 1 33 ? 6.025 5.585 8.819 1.00 13.22 ? 334 TYR X CD2 1 |
| ATOM 83 C CE1 . TYR A 1 33 ? 5.848 3.667 6.826 1.00 13.97 ? 334 TYR X CE1 1 |
| ATOM 84 C CE2 . TYR A 1 33 ? 4.788 5.079 8.455 1.00 13.83 ? 334 TYR X CE2 1 |
| ATOM 85 C CZ . TYR A 1 33 ? 4.702 4.121 7.473 1.00 14.38 ? 334 TYR X CZ 1 |
| ATOM 86 O OH . TYR A 1 33 ? 3.448 3.653 7.116 1.00 17.03 ? 334 TYR X OH 1 |
| ATOM 87 N N . PHE A 1 34 ? 8.967 2.620 9.563 1.00 14.24 ? 335 PHE X N 1 |
| ATOM 88 C CA . PHE A 1 34 ? 8.891 1.295 8.970 1.00 14.84 ? 335 PHE X CA 1 |
| ATOM 89 C C . PHE A 1 34 ? 7.587 0.716 9.547 1.00 15.41 ? 335 PHE X C 1 |
| ATOM 90 O O . PHE A 1 34 ? 7.490 0.455 10.750 1.00 16.36 ? 335 PHE X O 1 |
| ATOM 91 C CB . PHE A 1 34 ? 10.086 0.423 9.347 1.00 15.07 ? 335 PHE X CB 1 |
| ATOM 92 C CG . PHE A 1 34 ? 10.072 -0.913 8.675 1.00 16.04 ? 335 PHE X CG 1 |
| ATOM 93 C CD1 . PHE A 1 34 ? 10.253 -1.013 7.290 1.00 17.62 ? 335 PHE X CD1 1 |
| ATOM 94 C CD2 . PHE A 1 34 ? 9.851 -2.074 9.411 1.00 18.78 ? 335 PHE X CD2 1 |
| ATOM 95 C CE1 . PHE A 1 34 ? 10.231 -2.242 6.648 1.00 19.28 ? 335 PHE X CE1 1 |
| ATOM 96 C CE2 . PHE A 1 34 ? 9.828 -3.322 8.776 1.00 19.31 ? 335 PHE X CE2 1 |
| ATOM 97 C CZ . PHE A 1 34 ? 10.014 -3.402 7.396 1.00 17.81 ? 335 PHE X CZ 1 |
| ATOM 98 N N . ARG A 1 35 ? 6.594 0.606 8.672 1.00 16.34 ? 336 ARG X N 1 |
| ATOM 99 C CA A ARG A 1 35 ? 5.226 0.187 8.991 0.50 16.70 ? 336 ARG X CA 1 |
| ATOM 100 C CA B ARG A 1 35 ? 5.237 0.157 9.034 0.50 16.37 ? 336 ARG X CA 1 |
| ATOM 101 C C . ARG A 1 35 ? 4.459 1.212 9.832 1.00 16.23 ? 336 ARG X C 1 |
| ATOM 102 O O . ARG A 1 35 ? 3.240 1.289 9.731 1.00 17.28 ? 336 ARG X O 1 |
| ATOM 103 C CB A ARG A 1 35 ? 5.169 -1.218 9.616 0.50 16.74 ? 336 ARG X CB 1 |
| ATOM 104 C CB B ARG A 1 35 ? 5.231 -1.182 9.807 0.50 16.65 ? 336 ARG X CB 1 |
| ATOM 105 C CG A ARG A 1 35 ? 5.428 -2.353 8.627 0.50 17.39 ? 336 ARG X CG 1 |
| ATOM 106 C CG B ARG A 1 35 ? 6.156 -2.292 9.288 0.50 17.04 ? 336 ARG X CG 1 |
| ATOM 107 C CD A ARG A 1 35 ? 5.022 -3.706 9.204 0.50 18.24 ? 336 ARG X CD 1 |
| ATOM 108 C CD B ARG A 1 35 ? 6.082 -2.435 7.783 0.50 18.19 ? 336 ARG X CD 1 |
| ATOM 109 N NE A ARG A 1 35 ? 6.005 -4.240 10.150 0.50 22.01 ? 336 ARG X NE 1 |
| ATOM 110 N NE B ARG A 1 35 ? 6.700 -3.669 7.300 0.50 18.42 ? 336 ARG X NE 1 |
| ATOM 111 C CZ A ARG A 1 35 ? 6.667 -5.388 9.991 0.50 22.30 ? 336 ARG X CZ 1 |
| ATOM 112 C CZ B ARG A 1 35 ? 7.279 -3.797 6.109 0.50 17.58 ? 336 ARG X CZ 1 |
| ATOM 113 N NH1 A ARG A 1 35 ? 6.462 -6.149 8.920 0.50 23.92 ? 336 ARG X NH1 1 |
| ATOM 114 N NH1 B ARG A 1 35 ? 7.353 -2.757 5.277 0.50 16.55 ? 336 ARG X NH1 1 |
| ATOM 115 N NH2 A ARG A 1 35 ? 7.536 -5.782 10.911 0.50 23.03 ? 336 ARG X NH2 1 |
| ATOM 116 N NH2 B ARG A 1 35 ? 7.798 -4.966 5.755 0.50 19.30 ? 336 ARG X NH2 1 |
| ATOM 117 N N . GLN A 1 36 ? 5.173 2.008 10.631 1.00 15.52 ? 337 GLN X N 1 |
| ATOM 118 C CA . GLN A 1 36 ? 4.579 3.106 11.411 1.00 14.90 ? 337 GLN X CA 1 |
| ATOM 119 C C . GLN A 1 36 ? 5.736 4.027 11.832 1.00 13.63 ? 337 GLN X C 1 |
| ATOM 120 O O . GLN A 1 36 ? 6.894 3.615 11.742 1.00 13.40 ? 337 GLN X O 1 |
| ATOM 121 C CB . GLN A 1 36 ? 3.826 2.567 12.641 1.00 14.25 ? 337 GLN X CB 1 |
| ATOM 122 C CG . GLN A 1 36 ? 4.734 1.890 13.646 1.00 16.48 ? 337 GLN X CG 1 |
| ATOM 123 C CD . GLN A 1 36 ? 3.988 1.288 14.827 1.00 17.70 ? 337 GLN X CD 1 |
| ATOM 124 O OE1 . GLN A 1 36 ? 2.786 1.502 15.002 1.00 21.12 ? 337 GLN X OE1 1 |
| ATOM 125 N NE2 . GLN A 1 36 ? 4.705 0.530 15.637 1.00 22.72 ? 337 GLN X NE2 1 |
| ATOM 126 N N . SER A 1 37 ? 5.435 5.247 12.294 1.00 12.63 ? 338 SER X N 1 |
| ATOM 127 C CA . SER A 1 37 ? 6.484 6.138 12.794 1.00 13.20 ? 338 SER X CA 1 |
| ATOM 128 C C . SER A 1 37 ? 7.107 5.520 14.045 1.00 13.32 ? 338 SER X C 1 |
| ATOM 129 O O . SER A 1 37 ? 6.402 4.894 14.854 1.00 13.31 ? 338 SER X O 1 |
| ATOM 130 C CB . SER A 1 37 ? 5.915 7.524 13.090 1.00 12.54 ? 338 SER X CB 1 |
| ATOM 131 O OG . SER A 1 37 ? 5.336 8.085 11.927 1.00 12.93 ? 338 SER X OG 1 |
| ATOM 132 N N . LEU A 1 38 ? 8.413 5.730 14.196 1.00 13.83 ? 339 LEU X N 1 |
| ATOM 133 C CA . LEU A 1 38 ? 9.222 5.011 15.179 1.00 14.46 ? 339 LEU X CA 1 |
| ATOM 134 C C . LEU A 1 38 ? 9.651 5.944 16.295 1.00 15.39 ? 339 LEU X C 1 |
| ATOM 135 O O . LEU A 1 38 ? 9.654 7.169 16.134 1.00 15.16 ? 339 LEU X O 1 |
| ATOM 136 C CB . LEU A 1 38 ? 10.462 4.426 14.495 1.00 15.68 ? 339 LEU X CB 1 |
| ATOM 137 C CG . LEU A 1 38 ? 10.204 3.472 13.320 1.00 16.12 ? 339 LEU X CG 1 |
| ATOM 138 C CD1 . LEU A 1 38 ? 11.517 3.127 12.626 1.00 17.47 ? 339 LEU X CD1 1 |
| ATOM 139 C CD2 . LEU A 1 38 ? 9.474 2.229 13.779 1.00 17.58 ? 339 LEU X CD2 1 |
| ATOM 140 N N . SER A 1 39 ? 10.055 5.350 17.413 1.00 16.00 ? 340 SER X N 1 |
| ATOM 141 C CA . SER A 1 39 ? 10.467 6.112 18.591 1.00 17.20 ? 340 SER X CA 1 |
| ATOM 142 C C . SER A 1 39 ? 11.953 5.971 18.892 1.00 17.22 ? 340 SER X C 1 |
| ATOM 143 O O . SER A 1 39 ? 12.443 6.546 19.872 1.00 18.26 ? 340 SER X O 1 |
| ATOM 144 C CB . SER A 1 39 ? 9.650 5.675 19.818 1.00 18.31 ? 340 SER X CB 1 |
| ATOM 145 O OG . SER A 1 39 ? 8.277 5.985 19.646 1.00 19.15 ? 340 SER X OG 1 |
| ATOM 146 N N . TYR A 1 40 ? 12.674 5.219 18.060 1.00 17.13 ? 341 TYR X N 1 |
| ATOM 147 C CA . TYR A 1 40 ? 14.081 4.894 18.344 1.00 17.50 ? 341 TYR X CA 1 |
| ATOM 148 C C . TYR A 1 40 ? 14.971 6.118 18.412 1.00 17.11 ? 341 TYR X C 1 |
| ATOM 149 O O . TYR A 1 40 ? 14.817 7.048 17.617 1.00 17.21 ? 341 TYR X O 1 |
| ATOM 150 C CB . TYR A 1 40 ? 14.674 3.985 17.261 1.00 18.86 ? 341 TYR X CB 1 |
| ATOM 151 C CG . TYR A 1 40 ? 13.910 2.716 16.994 1.00 20.73 ? 341 TYR X CG 1 |
| ATOM 152 C CD1 . TYR A 1 40 ? 13.426 1.918 18.037 1.00 23.96 ? 341 TYR X CD1 1 |
| ATOM 153 C CD2 . TYR A 1 40 ? 13.702 2.296 15.685 1.00 22.15 ? 341 TYR X CD2 1 |
| ATOM 154 C CE1 . TYR A 1 40 ? 12.726 0.722 17.757 1.00 25.52 ? 341 TYR X CE1 1 |
| ATOM 155 C CE2 . TYR A 1 40 ? 13.024 1.125 15.400 1.00 25.11 ? 341 TYR X CE2 1 |
| ATOM 156 C CZ . TYR A 1 40 ? 12.533 0.352 16.427 1.00 24.00 ? 341 TYR X CZ 1 |
| ATOM 157 O OH . TYR A 1 40 ? 11.859 -0.803 16.098 1.00 26.07 ? 341 TYR X OH 1 |
| ATOM 158 N N . LEU A 1 41 ? 15.909 6.097 19.356 1.00 16.12 ? 342 LEU X N 1 |
| ATOM 159 C CA . LEU A 1 41 ? 17.068 6.974 19.319 1.00 15.78 ? 342 LEU X CA 1 |
| ATOM 160 C C . LEU A 1 41 ? 18.289 6.071 19.459 1.00 15.75 ? 342 LEU X C 1 |
| ATOM 161 O O . LEU A 1 41 ? 18.409 5.323 20.428 1.00 15.23 ? 342 LEU X O 1 |
| ATOM 162 C CB . LEU A 1 41 ? 17.033 8.017 20.443 1.00 15.36 ? 342 LEU X CB 1 |
| ATOM 163 C CG . LEU A 1 41 ? 18.314 8.850 20.576 1.00 16.76 ? 342 LEU X CG 1 |
| ATOM 164 C CD1 . LEU A 1 41 ? 18.539 9.764 19.347 1.00 16.00 ? 342 LEU X CD1 1 |
| ATOM 165 C CD2 . LEU A 1 41 ? 18.297 9.657 21.874 1.00 16.05 ? 342 LEU X CD2 1 |
| ATOM 166 N N . GLU A 1 42 ? 19.152 6.100 18.453 1.00 15.32 ? 343 GLU X N 1 |
| ATOM 167 C CA . GLU A 1 42 ? 20.348 5.252 18.426 1.00 16.67 ? 343 GLU X CA 1 |
| ATOM 168 C C . GLU A 1 42 ? 21.559 6.073 18.041 1.00 16.28 ? 343 GLU X C 1 |
| ATOM 169 O O . GLU A 1 42 ? 21.453 7.039 17.270 1.00 16.65 ? 343 GLU X O 1 |
| ATOM 170 C CB . GLU A 1 42 ? 20.165 4.084 17.457 1.00 16.90 ? 343 GLU X CB 1 |
| ATOM 171 C CG . GLU A 1 42 ? 19.027 3.153 17.863 1.00 17.84 ? 343 GLU X CG 1 |
| ATOM 172 C CD . GLU A 1 42 ? 18.755 2.062 16.840 1.00 19.74 ? 343 GLU X CD 1 |
| ATOM 173 O OE1 . GLU A 1 42 ? 18.370 2.398 15.704 1.00 22.21 ? 343 GLU X OE1 1 |
| ATOM 174 O OE2 . GLU A 1 42 ? 18.915 0.866 17.177 1.00 23.69 ? 343 GLU X OE2 1 |
| ATOM 175 N N . ALA A 1 43 ? 22.715 5.707 18.589 1.00 15.56 ? 344 ALA X N 1 |
| ATOM 176 C CA . ALA A 1 43 ? 23.940 6.454 18.307 1.00 15.67 ? 344 ALA X CA 1 |
| ATOM 177 C C . ALA A 1 43 ? 24.990 5.525 17.722 1.00 15.83 ? 344 ALA X C 1 |
| ATOM 178 O O . ALA A 1 43 ? 25.221 4.432 18.253 1.00 15.97 ? 344 ALA X O 1 |
| ATOM 179 C CB . ALA A 1 43 ? 24.473 7.146 19.580 1.00 15.88 ? 344 ALA X CB 1 |
| ATOM 180 N N . TYR A 1 44 ? 25.618 5.970 16.639 1.00 15.89 ? 345 TYR X N 1 |
| ATOM 181 C CA . TYR A 1 44 ? 26.678 5.218 15.981 1.00 16.40 ? 345 TYR X CA 1 |
| ATOM 182 C C . TYR A 1 44 ? 28.030 5.856 16.259 1.00 17.04 ? 345 TYR X C 1 |
| ATOM 183 O O . TYR A 1 44 ? 28.172 7.072 16.176 1.00 16.27 ? 345 TYR X O 1 |
| ATOM 184 C CB . TYR A 1 44 ? 26.424 5.156 14.466 1.00 16.91 ? 345 TYR X CB 1 |
| ATOM 185 C CG . TYR A 1 44 ? 27.522 4.458 13.691 1.00 17.11 ? 345 TYR X CG 1 |
| ATOM 186 C CD1 . TYR A 1 44 ? 27.792 3.108 13.898 1.00 16.84 ? 345 TYR X CD1 1 |
| ATOM 187 C CD2 . TYR A 1 44 ? 28.275 5.139 12.732 1.00 17.98 ? 345 TYR X CD2 1 |
| ATOM 188 C CE1 . TYR A 1 44 ? 28.803 2.463 13.194 1.00 17.92 ? 345 TYR X CE1 1 |
| ATOM 189 C CE2 . TYR A 1 44 ? 29.287 4.492 12.010 1.00 16.71 ? 345 TYR X CE2 1 |
| ATOM 190 C CZ . TYR A 1 44 ? 29.543 3.153 12.257 1.00 17.69 ? 345 TYR X CZ 1 |
| ATOM 191 O OH . TYR A 1 44 ? 30.534 2.490 11.561 1.00 19.70 ? 345 TYR X OH 1 |
| ATOM 192 N N . ASN A 1 45 ? 29.018 5.025 16.600 1.00 17.84 ? 346 ASN X N 1 |
| ATOM 193 C CA . ASN A 1 45 ? 30.383 5.501 16.780 1.00 19.34 ? 346 ASN X CA 1 |
| ATOM 194 C C . ASN A 1 45 ? 31.263 5.095 15.597 1.00 20.15 ? 346 ASN X C 1 |
| ATOM 195 O O . ASN A 1 45 ? 31.651 3.933 15.489 1.00 20.02 ? 346 ASN X O 1 |
| ATOM 196 C CB . ASN A 1 45 ? 30.971 4.978 18.099 1.00 19.55 ? 346 ASN X CB 1 |
| ATOM 197 C CG . ASN A 1 45 ? 32.297 5.631 18.442 1.00 21.28 ? 346 ASN X CG 1 |
| ATOM 198 O OD1 . ASN A 1 45 ? 32.950 6.234 17.590 1.00 21.96 ? 346 ASN X OD1 1 |
| ATOM 199 N ND2 . ASN A 1 45 ? 32.698 5.516 19.701 1.00 23.36 ? 346 ASN X ND2 1 |
| ATOM 200 N N . PRO A 1 46 ? 31.559 6.041 14.688 1.00 21.01 ? 347 PRO X N 1 |
| ATOM 201 C CA . PRO A 1 46 ? 32.351 5.687 13.503 1.00 22.34 ? 347 PRO X CA 1 |
| ATOM 202 C C . PRO A 1 46 ? 33.759 5.149 13.806 1.00 23.91 ? 347 PRO X C 1 |
| ATOM 203 O O . PRO A 1 46 ? 34.311 4.399 12.986 1.00 24.48 ? 347 PRO X O 1 |
| ATOM 204 C CB . PRO A 1 46 ? 32.435 7.008 12.729 1.00 22.75 ? 347 PRO X CB 1 |
| ATOM 205 C CG . PRO A 1 46 ? 31.253 7.792 13.202 1.00 21.39 ? 347 PRO X CG 1 |
| ATOM 206 C CD . PRO A 1 46 ? 31.148 7.456 14.662 1.00 21.24 ? 347 PRO X CD 1 |
| ATOM 207 N N . SER A 1 47 ? 34.317 5.526 14.961 1.00 24.52 ? 348 SER X N 1 |
| ATOM 208 C CA A SER A 1 47 ? 35.667 5.102 15.352 0.50 25.30 ? 348 SER X CA 1 |
| ATOM 209 C CA B SER A 1 47 ? 35.669 5.100 15.343 0.50 25.15 ? 348 SER X CA 1 |
| ATOM 210 C C . SER A 1 47 ? 35.761 3.598 15.600 1.00 25.46 ? 348 SER X C 1 |
| ATOM 211 O O . SER A 1 47 ? 36.760 2.967 15.243 1.00 26.36 ? 348 SER X O 1 |
| ATOM 212 C CB A SER A 1 47 ? 36.142 5.867 16.590 0.50 25.31 ? 348 SER X CB 1 |
| ATOM 213 C CB B SER A 1 47 ? 36.181 5.884 16.558 0.50 25.14 ? 348 SER X CB 1 |
| ATOM 214 O OG A SER A 1 47 ? 36.189 7.263 16.345 0.50 26.35 ? 348 SER X OG 1 |
| ATOM 215 O OG B SER A 1 47 ? 35.528 5.493 17.754 0.50 25.26 ? 348 SER X OG 1 |
| ATOM 216 N N . ASP A 1 48 ? 34.728 3.025 16.215 1.00 25.39 ? 349 ASP X N 1 |
| ATOM 217 C CA . ASP A 1 48 ? 34.738 1.591 16.532 1.00 25.50 ? 349 ASP X CA 1 |
| ATOM 218 C C . ASP A 1 48 ? 33.600 0.767 15.904 1.00 25.02 ? 349 ASP X C 1 |
| ATOM 219 O O . ASP A 1 48 ? 33.483 -0.440 16.142 1.00 24.87 ? 349 ASP X O 1 |
| ATOM 220 C CB . ASP A 1 48 ? 34.830 1.376 18.054 1.00 26.21 ? 349 ASP X CB 1 |
| ATOM 221 C CG . ASP A 1 48 ? 33.528 1.675 18.784 1.00 27.98 ? 349 ASP X CG 1 |
| ATOM 222 O OD1 . ASP A 1 48 ? 32.536 2.090 18.149 1.00 29.25 ? 349 ASP X OD1 1 |
| ATOM 223 O OD2 . ASP A 1 48 ? 33.500 1.482 20.019 1.00 31.13 ? 349 ASP X OD2 1 |
| ATOM 224 N N . GLY A 1 49 ? 32.756 1.426 15.114 1.00 24.38 ? 350 GLY X N 1 |
| ATOM 225 C CA . GLY A 1 49 ? 31.692 0.743 14.383 1.00 23.90 ? 350 GLY X CA 1 |
| ATOM 226 C C . GLY A 1 49 ? 30.523 0.238 15.213 1.00 23.52 ? 350 GLY X C 1 |
| ATOM 227 O O . GLY A 1 49 ? 29.746 -0.593 14.739 1.00 24.08 ? 350 GLY X O 1 |
| ATOM 228 N N . THR A 1 50 ? 30.375 0.747 16.436 1.00 22.72 ? 351 THR X N 1 |
| ATOM 229 C CA . THR A 1 50 ? 29.325 0.268 17.349 1.00 22.21 ? 351 THR X CA 1 |
| ATOM 230 C C . THR A 1 50 ? 28.076 1.150 17.388 1.00 21.33 ? 351 THR X C 1 |
| ATOM 231 O O . THR A 1 50 ? 28.157 2.370 17.217 1.00 20.65 ? 351 THR X O 1 |
| ATOM 232 C CB . THR A 1 50 ? 29.845 0.135 18.797 1.00 22.74 ? 351 THR X CB 1 |
| ATOM 233 O OG1 . THR A 1 50 ? 30.295 1.413 19.261 1.00 24.49 ? 351 THR X OG1 1 |
| ATOM 234 C CG2 . THR A 1 50 ? 30.979 -0.878 18.883 1.00 23.14 ? 351 THR X CG2 1 |
| ATOM 235 N N . TRP A 1 51 ? 26.936 0.511 17.646 1.00 20.27 ? 352 TRP X N 1 |
| ATOM 236 C CA . TRP A 1 51 ? 25.654 1.184 17.870 1.00 19.91 ? 352 TRP X CA 1 |
| ATOM 237 C C . TRP A 1 51 ? 25.236 1.081 19.336 1.00 20.27 ? 352 TRP X C 1 |
| ATOM 238 O O . TRP A 1 51 ? 25.462 0.055 19.984 1.00 20.48 ? 352 TRP X O 1 |
| ATOM 239 C CB . TRP A 1 51 ? 24.570 0.535 17.016 1.00 19.66 ? 352 TRP X CB 1 |
| ATOM 240 C CG . TRP A 1 51 ? 24.651 0.873 15.569 1.00 19.81 ? 352 TRP X CG 1 |
| ATOM 241 C CD1 . TRP A 1 51 ? 25.298 0.172 14.596 1.00 19.52 ? 352 TRP X CD1 1 |
| ATOM 242 C CD2 . TRP A 1 51 ? 24.061 2.006 14.926 1.00 19.23 ? 352 TRP X CD2 1 |
| ATOM 243 N NE1 . TRP A 1 51 ? 25.137 0.792 13.372 1.00 18.97 ? 352 TRP X NE1 1 |
| ATOM 244 C CE2 . TRP A 1 51 ? 24.387 1.925 13.552 1.00 18.86 ? 352 TRP X CE2 1 |
| ATOM 245 C CE3 . TRP A 1 51 ? 23.286 3.084 15.378 1.00 19.53 ? 352 TRP X CE3 1 |
| ATOM 246 C CZ2 . TRP A 1 51 ? 23.959 2.875 12.624 1.00 18.84 ? 352 TRP X CZ2 1 |
| ATOM 247 C CZ3 . TRP A 1 51 ? 22.866 4.035 14.456 1.00 19.12 ? 352 TRP X CZ3 1 |
| ATOM 248 C CH2 . TRP A 1 51 ? 23.202 3.920 13.089 1.00 18.02 ? 352 TRP X CH2 1 |
| ATOM 249 N N . LEU A 1 52 ? 24.617 2.140 19.843 1.00 20.20 ? 353 LEU X N 1 |
| ATOM 250 C CA . LEU A 1 52 ? 24.088 2.166 21.197 1.00 20.73 ? 353 LEU X CA 1 |
| ATOM 251 C C . LEU A 1 52 ? 22.628 2.588 21.110 1.00 20.23 ? 353 LEU X C 1 |
| ATOM 252 O O . LEU A 1 52 ? 22.308 3.577 20.440 1.00 20.28 ? 353 LEU X O 1 |
| ATOM 253 C CB . LEU A 1 52 ? 24.858 3.184 22.047 1.00 21.63 ? 353 LEU X CB 1 |
| ATOM 254 C CG . LEU A 1 52 ? 25.163 2.900 23.528 1.00 24.65 ? 353 LEU X CG 1 |
| ATOM 255 C CD1 . LEU A 1 52 ? 25.380 4.217 24.272 1.00 26.64 ? 353 LEU X CD1 1 |
| ATOM 256 C CD2 . LEU A 1 52 ? 24.098 2.059 24.229 1.00 26.36 ? 353 LEU X CD2 1 |
| ATOM 257 N N . ARG A 1 53 ? 21.736 1.854 21.770 1.00 19.33 ? 354 ARG X N 1 |
| ATOM 258 C CA . ARG A 1 53 ? 20.353 2.299 21.858 1.00 19.41 ? 354 ARG X CA 1 |
| ATOM 259 C C . ARG A 1 53 ? 20.179 3.195 23.071 1.00 19.15 ? 354 ARG X C 1 |
| ATOM 260 O O . ARG A 1 53 ? 20.599 2.847 24.184 1.00 19.20 ? 354 ARG X O 1 |
| ATOM 261 C CB . ARG A 1 53 ? 19.357 1.130 21.883 1.00 20.30 ? 354 ARG X CB 1 |
| ATOM 262 C CG . ARG A 1 53 ? 17.911 1.591 22.041 1.00 22.97 ? 354 ARG X CG 1 |
| ATOM 263 C CD . ARG A 1 53 ? 16.989 0.964 21.039 1.00 26.72 ? 354 ARG X CD 1 |
| ATOM 264 N NE . ARG A 1 53 ? 15.617 1.418 21.242 1.00 26.29 ? 354 ARG X NE 1 |
| ATOM 265 C CZ . ARG A 1 53 ? 14.577 0.612 21.436 1.00 27.91 ? 354 ARG X CZ 1 |
| ATOM 266 N NH1 . ARG A 1 53 ? 14.740 -0.711 21.447 1.00 28.12 ? 354 ARG X NH1 1 |
| ATOM 267 N NH2 . ARG A 1 53 ? 13.367 1.125 21.608 1.00 27.23 ? 354 ARG X NH2 1 |
| ATOM 268 N N . LEU A 1 54 ? 19.572 4.355 22.834 1.00 17.83 ? 355 LEU X N 1 |
| ATOM 269 C CA . LEU A 1 54 ? 19.363 5.366 23.867 1.00 17.43 ? 355 LEU X CA 1 |
| ATOM 270 C C . LEU A 1 54 ? 17.880 5.568 24.184 1.00 16.76 ? 355 LEU X C 1 |
| ATOM 271 O O . LEU A 1 54 ? 17.030 4.816 23.698 1.00 17.32 ? 355 LEU X O 1 |
| ATOM 272 C CB . LEU A 1 54 ? 20.038 6.674 23.455 1.00 17.38 ? 355 LEU X CB 1 |
| ATOM 273 C CG . LEU A 1 54 ? 21.554 6.532 23.233 1.00 18.04 ? 355 LEU X CG 1 |
| ATOM 274 C CD1 . LEU A 1 54 ? 22.115 7.749 22.520 1.00 18.94 ? 355 LEU X CD1 1 |
| ATOM 275 C CD2 . LEU A 1 54 ? 22.295 6.268 24.548 1.00 18.26 ? 355 LEU X CD2 1 |
| ATOM 276 N N . ALA A 1 55 ? 17.567 6.565 25.016 1.00 16.26 ? 356 ALA X N 1 |
| ATOM 277 C CA . ALA A 1 55 ? 16.181 6.828 25.409 1.00 15.97 ? 356 ALA X CA 1 |
| ATOM 278 C C . ALA A 1 55 ? 15.257 7.053 24.213 1.00 16.23 ? 356 ALA X C 1 |
| ATOM 279 O O . ALA A 1 55 ? 15.556 7.869 23.342 1.00 16.06 ? 356 ALA X O 1 |
| ATOM 280 C CB . ALA A 1 55 ? 16.102 8.036 26.349 1.00 15.87 ? 356 ALA X CB 1 |
| ATOM 281 N N . ASP A 1 56 ? 14.129 6.345 24.191 1.00 16.92 ? 357 ASP X N 1 |
| ATOM 282 C CA . ASP A 1 56 ? 13.095 6.571 23.165 1.00 17.43 ? 357 ASP X CA 1 |
| ATOM 283 C C . ASP A 1 56 ? 12.583 8.012 23.151 1.00 17.30 ? 357 ASP X C 1 |
| ATOM 284 O O . ASP A 1 56 ? 12.450 8.663 24.208 1.00 17.02 ? 357 ASP X O 1 |
| ATOM 285 C CB . ASP A 1 56 ? 11.869 5.691 23.411 1.00 17.48 ? 357 ASP X CB 1 |
| ATOM 286 C CG . ASP A 1 56 ? 12.001 4.280 22.851 1.00 21.09 ? 357 ASP X CG 1 |
| ATOM 287 O OD1 . ASP A 1 56 ? 13.052 3.894 22.291 1.00 21.79 ? 357 ASP X OD1 1 |
| ATOM 288 O OD2 . ASP A 1 56 ? 11.005 3.533 22.994 1.00 24.30 ? 357 ASP X OD2 1 |
| ATOM 289 N N . LEU A 1 57 ? 12.268 8.495 21.948 1.00 17.22 ? 358 LEU X N 1 |
| ATOM 290 C CA . LEU A 1 57 ? 11.429 9.673 21.803 1.00 17.84 ? 358 LEU X CA 1 |
| ATOM 291 C C . LEU A 1 57 ? 10.140 9.498 22.621 1.00 18.04 ? 358 LEU X C 1 |
| ATOM 292 O O . LEU A 1 57 ? 9.603 8.391 22.737 1.00 18.26 ? 358 LEU X O 1 |
| ATOM 293 C CB . LEU A 1 57 ? 11.049 9.881 20.341 1.00 17.41 ? 358 LEU X CB 1 |
| ATOM 294 C CG . LEU A 1 57 ? 12.177 10.385 19.430 1.00 17.31 ? 358 LEU X CG 1 |
| ATOM 295 C CD1 . LEU A 1 57 ? 11.851 10.052 17.996 1.00 18.11 ? 358 LEU X CD1 1 |
| ATOM 296 C CD2 . LEU A 1 57 ? 12.376 11.889 19.592 1.00 17.53 ? 358 LEU X CD2 1 |
| ATOM 297 N N . GLN A 1 58 ? 9.640 10.593 23.176 1.00 18.87 ? 359 GLN X N 1 |
| ATOM 298 C CA . GLN A 1 58 ? 8.397 10.524 23.955 1.00 19.93 ? 359 GLN X CA 1 |
| ATOM 299 C C . GLN A 1 58 ? 7.152 10.311 23.089 1.00 19.15 ? 359 GLN X C 1 |
| ATOM 300 O O . GLN A 1 58 ? 6.156 9.753 23.555 1.00 19.75 ? 359 GLN X O 1 |
| ATOM 301 C CB . GLN A 1 58 ? 8.252 11.747 24.866 1.00 20.32 ? 359 GLN X CB 1 |
| ATOM 302 C CG . GLN A 1 58 ? 9.444 11.911 25.808 1.00 22.36 ? 359 GLN X CG 1 |
| ATOM 303 C CD . GLN A 1 58 ? 9.245 12.994 26.864 1.00 22.88 ? 359 GLN X CD 1 |
| ATOM 304 O OE1 . GLN A 1 58 ? 8.738 14.091 26.583 1.00 28.04 ? 359 GLN X OE1 1 |
| ATOM 305 N NE2 . GLN A 1 58 ? 9.666 12.693 28.086 1.00 26.73 ? 359 GLN X NE2 1 |
| ATOM 306 N N . VAL A 1 59 ? 7.222 10.747 21.832 1.00 18.33 ? 360 VAL X N 1 |
| ATOM 307 C CA . VAL A 1 59 ? 6.155 10.523 20.851 1.00 17.31 ? 360 VAL X CA 1 |
| ATOM 308 C C . VAL A 1 59 ? 6.830 10.033 19.559 1.00 16.59 ? 360 VAL X C 1 |
| ATOM 309 O O . VAL A 1 59 ? 7.847 10.593 19.161 1.00 16.13 ? 360 VAL X O 1 |
| ATOM 310 C CB . VAL A 1 59 ? 5.374 11.836 20.562 1.00 17.99 ? 360 VAL X CB 1 |
| ATOM 311 C CG1 . VAL A 1 59 ? 4.227 11.625 19.574 1.00 17.59 ? 360 VAL X CG1 1 |
| ATOM 312 C CG2 . VAL A 1 59 ? 4.825 12.443 21.854 1.00 17.86 ? 360 VAL X CG2 1 |
| ATOM 313 N N . PRO A 1 60 ? 6.277 8.984 18.912 1.00 15.67 ? 361 PRO X N 1 |
| ATOM 314 C CA . PRO A 1 60 ? 6.927 8.502 17.671 1.00 15.00 ? 361 PRO X CA 1 |
| ATOM 315 C C . PRO A 1 60 ? 6.943 9.592 16.601 1.00 15.08 ? 361 PRO X C 1 |
| ATOM 316 O O . PRO A 1 60 ? 6.046 10.436 16.573 1.00 15.30 ? 361 PRO X O 1 |
| ATOM 317 C CB . PRO A 1 60 ? 6.016 7.363 17.218 1.00 15.96 ? 361 PRO X CB 1 |
| ATOM 318 C CG . PRO A 1 60 ? 5.297 6.929 18.473 1.00 15.98 ? 361 PRO X CG 1 |
| ATOM 319 C CD . PRO A 1 60 ? 5.088 8.183 19.255 1.00 15.99 ? 361 PRO X CD 1 |
| ATOM 320 N N . ARG A 1 61 ? 7.972 9.592 15.754 1.00 14.44 ? 362 ARG X N 1 |
| ATOM 321 C CA . ARG A 1 61 ? 8.147 10.662 14.777 1.00 15.54 ? 362 ARG X CA 1 |
| ATOM 322 C C . ARG A 1 61 ? 8.811 10.126 13.529 1.00 14.26 ? 362 ARG X C 1 |
| ATOM 323 O O . ARG A 1 61 ? 9.815 9.444 13.632 1.00 14.52 ? 362 ARG X O 1 |
| ATOM 324 C CB . ARG A 1 61 ? 9.104 11.772 15.294 1.00 15.93 ? 362 ARG X CB 1 |
| ATOM 325 C CG . ARG A 1 61 ? 9.141 12.126 16.757 1.00 20.03 ? 362 ARG X CG 1 |
| ATOM 326 C CD . ARG A 1 61 ? 8.245 13.285 17.055 1.00 22.16 ? 362 ARG X CD 1 |
| ATOM 327 N NE . ARG A 1 61 ? 8.721 14.576 16.533 1.00 21.33 ? 362 ARG X NE 1 |
| ATOM 328 C CZ . ARG A 1 61 ? 9.466 15.445 17.218 1.00 19.85 ? 362 ARG X CZ 1 |
| ATOM 329 N NH1 . ARG A 1 61 ? 9.886 15.165 18.449 1.00 18.73 ? 362 ARG X NH1 1 |
| ATOM 330 N NH2 . ARG A 1 61 ? 9.780 16.614 16.677 1.00 16.23 ? 362 ARG X NH2 1 |
| ATOM 331 N N . SER A 1 62 ? 8.278 10.476 12.368 1.00 13.69 ? 363 SER X N 1 |
| ATOM 332 C CA . SER A 1 62 ? 8.990 10.281 11.092 1.00 13.23 ? 363 SER X CA 1 |
| ATOM 333 C C . SER A 1 62 ? 8.884 11.575 10.316 1.00 12.88 ? 363 SER X C 1 |
| ATOM 334 O O . SER A 1 62 ? 8.004 12.379 10.581 1.00 13.31 ? 363 SER X O 1 |
| ATOM 335 C CB . SER A 1 62 ? 8.407 9.114 10.284 1.00 13.98 ? 363 SER X CB 1 |
| ATOM 336 O OG . SER A 1 62 ? 7.019 9.255 10.067 1.00 14.62 ? 363 SER X OG 1 |
| ATOM 337 N N . GLY A 1 63 ? 9.786 11.795 9.365 1.00 12.64 ? 364 GLY X N 1 |
| ATOM 338 C CA . GLY A 1 63 ? 9.739 13.036 8.595 1.00 12.87 ? 364 GLY X CA 1 |
| ATOM 339 C C . GLY A 1 63 ? 10.181 14.248 9.384 1.00 12.99 ? 364 GLY X C 1 |
| ATOM 340 O O . GLY A 1 63 ? 9.888 15.395 9.010 1.00 13.18 ? 364 GLY X O 1 |
| ATOM 341 N N . LEU A 1 64 ? 10.861 13.986 10.499 1.00 12.73 ? 365 LEU X N 1 |
| ATOM 342 C CA . LEU A 1 64 ? 11.439 15.036 11.346 1.00 13.08 ? 365 LEU X CA 1 |
| ATOM 343 C C . LEU A 1 64 ? 12.830 15.417 10.852 1.00 13.60 ? 365 LEU X C 1 |
| ATOM 344 O O . LEU A 1 64 ? 13.369 14.825 9.917 1.00 13.78 ? 365 LEU X O 1 |
| ATOM 345 C CB . LEU A 1 64 ? 11.523 14.582 12.805 1.00 13.17 ? 365 LEU X CB 1 |
| ATOM 346 C CG . LEU A 1 64 ? 12.569 13.523 13.131 1.00 12.76 ? 365 LEU X CG 1 |
| ATOM 347 C CD1 . LEU A 1 64 ? 12.839 13.513 14.647 1.00 14.18 ? 365 LEU X CD1 1 |
| ATOM 348 C CD2 . LEU A 1 64 ? 12.152 12.136 12.673 1.00 14.86 ? 365 LEU X CD2 1 |
| ATOM 349 N N . ALA A 1 65 ? 13.391 16.441 11.479 1.00 13.76 ? 366 ALA X N 1 |
| ATOM 350 C CA . ALA A 1 65 ? 14.794 16.757 11.263 1.00 14.07 ? 366 ALA X CA 1 |
| ATOM 351 C C . ALA A 1 65 ? 15.499 16.839 12.599 1.00 14.36 ? 366 ALA X C 1 |
| ATOM 352 O O . ALA A 1 65 ? 14.888 17.186 13.621 1.00 14.78 ? 366 ALA X O 1 |
| ATOM 353 C CB . ALA A 1 65 ? 14.952 18.064 10.513 1.00 14.83 ? 366 ALA X CB 1 |
| ATOM 354 N N . GLY A 1 66 ? 16.789 16.505 12.578 1.00 14.26 ? 367 GLY X N 1 |
| ATOM 355 C CA . GLY A 1 66 ? 17.645 16.663 13.756 1.00 14.28 ? 367 GLY X CA 1 |
| ATOM 356 C C . GLY A 1 66 ? 18.674 17.762 13.551 1.00 14.75 ? 367 GLY X C 1 |
| ATOM 357 O O . GLY A 1 66 ? 19.083 18.043 12.424 1.00 15.50 ? 367 GLY X O 1 |
| ATOM 358 N N . CYS A 1 67 ? 19.086 18.383 14.652 1.00 15.09 ? 368 CYS X N 1 |
| ATOM 359 C CA . CYS A 1 67 ? 20.199 19.322 14.638 1.00 15.34 ? 368 CYS X CA 1 |
| ATOM 360 C C . CYS A 1 67 ? 20.767 19.410 16.047 1.00 15.42 ? 368 CYS X C 1 |
| ATOM 361 O O . CYS A 1 67 ? 20.208 18.835 16.991 1.00 15.26 ? 368 CYS X O 1 |
| ATOM 362 C CB . CYS A 1 67 ? 19.765 20.703 14.132 1.00 16.00 ? 368 CYS X CB 1 |
| ATOM 363 S SG . CYS A 1 67 ? 18.550 21.530 15.198 1.00 18.23 ? 368 CYS X SG 1 |
| ATOM 364 N N . VAL A 1 68 ? 21.885 20.110 16.164 1.00 16.02 ? 369 VAL X N 1 |
| ATOM 365 C CA . VAL A 1 68 ? 22.562 20.262 17.447 1.00 16.22 ? 369 VAL X CA 1 |
| ATOM 366 C C . VAL A 1 68 ? 22.853 21.729 17.686 1.00 16.44 ? 369 VAL X C 1 |
| ATOM 367 O O . VAL A 1 68 ? 23.254 22.449 16.777 1.00 16.64 ? 369 VAL X O 1 |
| ATOM 368 C CB . VAL A 1 68 ? 23.882 19.442 17.490 1.00 16.64 ? 369 VAL X CB 1 |
| ATOM 369 C CG1 . VAL A 1 68 ? 24.759 19.829 18.684 1.00 17.47 ? 369 VAL X CG1 1 |
| ATOM 370 C CG2 . VAL A 1 68 ? 23.582 17.952 17.510 1.00 17.46 ? 369 VAL X CG2 1 |
| ATOM 371 N N . VAL A 1 69 ? 22.615 22.168 18.917 1.00 16.12 ? 370 VAL X N 1 |
| ATOM 372 C CA . VAL A 1 69 ? 23.027 23.510 19.362 1.00 16.87 ? 370 VAL X CA 1 |
| ATOM 373 C C . VAL A 1 69 ? 23.574 23.344 20.769 1.00 17.05 ? 370 VAL X C 1 |
| ATOM 374 O O . VAL A 1 69 ? 22.905 22.755 21.614 1.00 16.34 ? 370 VAL X O 1 |
| ATOM 375 C CB . VAL A 1 69 ? 21.854 24.518 19.420 1.00 16.92 ? 370 VAL X CB 1 |
| ATOM 376 C CG1 . VAL A 1 69 ? 22.342 25.898 19.877 1.00 18.04 ? 370 VAL X CG1 1 |
| ATOM 377 C CG2 . VAL A 1 69 ? 21.102 24.610 18.085 1.00 18.37 ? 370 VAL X CG2 1 |
| ATOM 378 N N . GLY A 1 70 ? 24.785 23.847 21.013 1.00 17.82 ? 371 GLY X N 1 |
| ATOM 379 C CA . GLY A 1 70 ? 25.393 23.797 22.353 1.00 18.39 ? 371 GLY X CA 1 |
| ATOM 380 C C . GLY A 1 70 ? 25.436 22.409 22.965 1.00 18.69 ? 371 GLY X C 1 |
| ATOM 381 O O . GLY A 1 70 ? 25.175 22.239 24.166 1.00 19.31 ? 371 GLY X O 1 |
| ATOM 382 N N . GLY A 1 71 ? 25.760 21.412 22.144 1.00 18.20 ? 372 GLY X N 1 |
| ATOM 383 C CA . GLY A 1 71 ? 25.905 20.039 22.632 1.00 17.74 ? 372 GLY X CA 1 |
| ATOM 384 C C . GLY A 1 71 ? 24.599 19.294 22.888 1.00 17.64 ? 372 GLY X C 1 |
| ATOM 385 O O . GLY A 1 71 ? 24.618 18.147 23.364 1.00 18.39 ? 372 GLY X O 1 |
| ATOM 386 N N . LEU A 1 72 ? 23.469 19.930 22.577 1.00 16.45 ? 373 LEU X N 1 |
| ATOM 387 C CA . LEU A 1 72 ? 22.158 19.300 22.759 1.00 16.27 ? 373 LEU X CA 1 |
| ATOM 388 C C . LEU A 1 72 ? 21.544 18.945 21.405 1.00 15.61 ? 373 LEU X C 1 |
| ATOM 389 O O . LEU A 1 72 ? 21.639 19.725 20.460 1.00 15.84 ? 373 LEU X O 1 |
| ATOM 390 C CB . LEU A 1 72 ? 21.206 20.215 23.528 1.00 15.88 ? 373 LEU X CB 1 |
| ATOM 391 C CG . LEU A 1 72 ? 21.671 20.653 24.925 1.00 17.09 ? 373 LEU X CG 1 |
| ATOM 392 C CD1 . LEU A 1 72 ? 20.690 21.663 25.486 1.00 17.18 ? 373 LEU X CD1 1 |
| ATOM 393 C CD2 . LEU A 1 72 ? 21.814 19.461 25.864 1.00 17.77 ? 373 LEU X CD2 1 |
| ATOM 394 N N . LEU A 1 73 ? 20.918 17.776 21.333 1.00 15.07 ? 374 LEU X N 1 |
| ATOM 395 C CA . LEU A 1 73 ? 20.283 17.298 20.101 1.00 15.21 ? 374 LEU X CA 1 |
| ATOM 396 C C . LEU A 1 73 ? 18.833 17.721 20.103 1.00 15.53 ? 374 LEU X C 1 |
| ATOM 397 O O . LEU A 1 73 ? 18.146 17.548 21.113 1.00 16.79 ? 374 LEU X O 1 |
| ATOM 398 C CB . LEU A 1 73 ? 20.370 15.763 20.063 1.00 15.26 ? 374 LEU X CB 1 |
| ATOM 399 C CG . LEU A 1 73 ? 19.559 14.990 19.017 1.00 16.10 ? 374 LEU X CG 1 |
| ATOM 400 C CD1 . LEU A 1 73 ? 20.095 15.283 17.628 1.00 18.59 ? 374 LEU X CD1 1 |
| ATOM 401 C CD2 . LEU A 1 73 ? 19.578 13.488 19.300 1.00 16.76 ? 374 LEU X CD2 1 |
| ATOM 402 N N . TYR A 1 74 ? 18.372 18.303 18.992 1.00 14.50 ? 375 TYR X N 1 |
| ATOM 403 C CA . TYR A 1 74 ? 16.971 18.673 18.864 1.00 14.57 ? 375 TYR X CA 1 |
| ATOM 404 C C . TYR A 1 74 ? 16.289 17.839 17.790 1.00 14.47 ? 375 TYR X C 1 |
| ATOM 405 O O . TYR A 1 74 ? 16.856 17.621 16.712 1.00 15.01 ? 375 TYR X O 1 |
| ATOM 406 C CB . TYR A 1 74 ? 16.819 20.148 18.513 1.00 15.12 ? 375 TYR X CB 1 |
| ATOM 407 C CG . TYR A 1 74 ? 17.239 21.062 19.637 1.00 15.24 ? 375 TYR X CG 1 |
| ATOM 408 C CD1 . TYR A 1 74 ? 18.578 21.440 19.793 1.00 15.84 ? 375 TYR X CD1 1 |
| ATOM 409 C CD2 . TYR A 1 74 ? 16.304 21.551 20.542 1.00 15.70 ? 375 TYR X CD2 1 |
| ATOM 410 C CE1 . TYR A 1 74 ? 18.977 22.275 20.839 1.00 15.82 ? 375 TYR X CE1 1 |
| ATOM 411 C CE2 . TYR A 1 74 ? 16.680 22.406 21.574 1.00 17.19 ? 375 TYR X CE2 1 |
| ATOM 412 C CZ . TYR A 1 74 ? 18.018 22.765 21.717 1.00 16.51 ? 375 TYR X CZ 1 |
| ATOM 413 O OH . TYR A 1 74 ? 18.402 23.601 22.744 1.00 17.24 ? 375 TYR X OH 1 |
| ATOM 414 N N . ALA A 1 75 ? 15.081 17.391 18.102 1.00 13.62 ? 376 ALA X N 1 |
| ATOM 415 C CA . ALA A 1 75 ? 14.203 16.715 17.148 1.00 13.80 ? 376 ALA X CA 1 |
| ATOM 416 C C . ALA A 1 75 ? 13.056 17.672 16.830 1.00 13.68 ? 376 ALA X C 1 |
| ATOM 417 O O . ALA A 1 75 ? 12.339 18.119 17.729 1.00 13.97 ? 376 ALA X O 1 |
| ATOM 418 C CB . ALA A 1 75 ? 13.671 15.417 17.747 1.00 14.22 ? 376 ALA X CB 1 |
| ATOM 419 N N . VAL A 1 76 ? 12.882 17.982 15.539 1.00 13.47 ? 377 VAL X N 1 |
| ATOM 420 C CA . VAL A 1 76 ? 11.988 19.058 15.117 1.00 13.92 ? 377 VAL X CA 1 |
| ATOM 421 C C . VAL A 1 76 ? 10.944 18.566 14.102 1.00 13.79 ? 377 VAL X C 1 |
| ATOM 422 O O . VAL A 1 76 ? 11.299 17.962 13.090 1.00 13.47 ? 377 VAL X O 1 |
| ATOM 423 C CB . VAL A 1 76 ? 12.789 20.195 14.416 1.00 14.51 ? 377 VAL X CB 1 |
| ATOM 424 C CG1 . VAL A 1 76 ? 11.974 21.464 14.392 1.00 15.29 ? 377 VAL X CG1 1 |
| ATOM 425 C CG2 . VAL A 1 76 ? 14.152 20.458 15.093 1.00 16.18 ? 377 VAL X CG2 1 |
| ATOM 426 N N . GLY A 1 77 ? 9.662 18.815 14.385 1.00 13.30 ? 378 GLY X N 1 |
| ATOM 427 C CA . GLY A 1 77 ? 8.585 18.522 13.432 1.00 12.96 ? 378 GLY X CA 1 |
| ATOM 428 C C . GLY A 1 77 ? 8.421 17.030 13.172 1.00 13.34 ? 378 GLY X C 1 |
| ATOM 429 O O . GLY A 1 77 ? 8.678 16.203 14.064 1.00 13.40 ? 378 GLY X O 1 |
| ATOM 430 N N . GLY A 1 78 ? 7.993 16.698 11.957 1.00 13.16 ? 379 GLY X N 1 |
| ATOM 431 C CA . GLY A 1 78 ? 7.697 15.325 11.575 1.00 13.19 ? 379 GLY X CA 1 |
| ATOM 432 C C . GLY A 1 78 ? 6.227 15.024 11.756 1.00 13.59 ? 379 GLY X C 1 |
| ATOM 433 O O . GLY A 1 78 ? 5.372 15.921 11.732 1.00 14.01 ? 379 GLY X O 1 |
| ATOM 434 N N . ARG A 1 79 ? 5.918 13.743 11.917 1.00 13.45 ? 380 ARG X N 1 |
| ATOM 435 C CA . ARG A 1 79 ? 4.543 13.317 12.122 1.00 14.14 ? 380 ARG X CA 1 |
| ATOM 436 C C . ARG A 1 79 ? 4.547 11.962 12.781 1.00 14.50 ? 380 ARG X C 1 |
| ATOM 437 O O . ARG A 1 79 ? 5.539 11.227 12.720 1.00 15.12 ? 380 ARG X O 1 |
| ATOM 438 C CB . ARG A 1 79 ? 3.757 13.270 10.812 1.00 14.77 ? 380 ARG X CB 1 |
| ATOM 439 C CG . ARG A 1 79 ? 4.088 12.131 9.845 1.00 16.90 ? 380 ARG X CG 1 |
| ATOM 440 C CD . ARG A 1 79 ? 3.124 12.225 8.668 1.00 18.69 ? 380 ARG X CD 1 |
| ATOM 441 N NE . ARG A 1 79 ? 3.294 11.185 7.655 1.00 20.41 ? 380 ARG X NE 1 |
| ATOM 442 C CZ . ARG A 1 79 ? 2.703 11.210 6.461 1.00 19.70 ? 380 ARG X CZ 1 |
| ATOM 443 N NH1 . ARG A 1 79 ? 2.903 10.220 5.599 1.00 22.15 ? 380 ARG X NH1 1 |
| ATOM 444 N NH2 . ARG A 1 79 ? 1.913 12.232 6.125 1.00 22.08 ? 380 ARG X NH2 1 |
| ATOM 445 N N . ASN A 1 80 ? 3.436 11.654 13.436 1.00 14.25 ? 381 ASN X N 1 |
| ATOM 446 C CA . ASN A 1 80 ? 3.232 10.334 14.000 1.00 14.68 ? 381 ASN X CA 1 |
| ATOM 447 C C . ASN A 1 80 ? 2.167 9.633 13.184 1.00 14.89 ? 381 ASN X C 1 |
| ATOM 448 O O . ASN A 1 80 ? 0.958 9.818 13.411 1.00 15.71 ? 381 ASN X O 1 |
| ATOM 449 C CB . ASN A 1 80 ? 2.852 10.403 15.482 1.00 15.22 ? 381 ASN X CB 1 |
| ATOM 450 C CG . ASN A 1 80 ? 2.594 9.025 16.073 1.00 16.09 ? 381 ASN X CG 1 |
| ATOM 451 O OD1 . ASN A 1 80 ? 2.912 8.003 15.459 1.00 16.81 ? 381 ASN X OD1 1 |
| ATOM 452 N ND2 . ASN A 1 80 ? 2.017 9.000 17.275 1.00 18.58 ? 381 ASN X ND2 1 |
| ATOM 453 N N . ASN A 1 81 ? 2.646 8.837 12.225 1.00 15.06 ? 382 ASN X N 1 |
| ATOM 454 C CA . ASN A 1 81 ? 1.808 8.087 11.311 1.00 15.64 ? 382 ASN X CA 1 |
| ATOM 455 C C . ASN A 1 81 ? 1.713 6.641 11.786 1.00 15.95 ? 382 ASN X C 1 |
| ATOM 456 O O . ASN A 1 81 ? 2.686 5.880 11.717 1.00 16.02 ? 382 ASN X O 1 |
| ATOM 457 C CB . ASN A 1 81 ? 2.388 8.170 9.890 1.00 16.35 ? 382 ASN X CB 1 |
| ATOM 458 C CG . ASN A 1 81 ? 1.496 7.518 8.855 1.00 18.09 ? 382 ASN X CG 1 |
| ATOM 459 O OD1 . ASN A 1 81 ? 0.367 7.117 9.150 1.00 19.84 ? 382 ASN X OD1 1 |
| ATOM 460 N ND2 . ASN A 1 81 ? 1.999 7.411 7.621 1.00 17.38 ? 382 ASN X ND2 1 |
| ATOM 461 N N . SER A 1 82 ? 0.538 6.276 12.291 1.00 17.08 ? 383 SER X N 1 |
| ATOM 462 C CA . SER A 1 82 ? 0.335 4.935 12.829 1.00 19.07 ? 383 SER X CA 1 |
| ATOM 463 C C . SER A 1 82 ? -1.030 4.428 12.401 1.00 19.58 ? 383 SER X C 1 |
| ATOM 464 O O . SER A 1 82 ? -1.840 5.193 11.896 1.00 18.69 ? 383 SER X O 1 |
| ATOM 465 C CB . SER A 1 82 ? 0.414 4.948 14.356 1.00 20.12 ? 383 SER X CB 1 |
| ATOM 466 O OG . SER A 1 82 ? -0.776 5.467 14.918 1.00 22.37 ? 383 SER X OG 1 |
| ATOM 467 N N . PRO A 1 83 ? -1.296 3.135 12.618 1.00 20.96 ? 384 PRO X N 1 |
| ATOM 468 C CA . PRO A 1 83 ? -2.593 2.573 12.245 1.00 21.87 ? 384 PRO X CA 1 |
| ATOM 469 C C . PRO A 1 83 ? -3.769 3.214 12.977 1.00 22.56 ? 384 PRO X C 1 |
| ATOM 470 O O . PRO A 1 83 ? -4.912 3.061 12.538 1.00 23.24 ? 384 PRO X O 1 |
| ATOM 471 C CB . PRO A 1 83 ? -2.461 1.098 12.654 1.00 21.38 ? 384 PRO X CB 1 |
| ATOM 472 C CG . PRO A 1 83 ? -1.388 1.103 13.704 1.00 22.38 ? 384 PRO X CG 1 |
| ATOM 473 C CD . PRO A 1 83 ? -0.411 2.123 13.225 1.00 21.69 ? 384 PRO X CD 1 |
| ATOM 474 N N . ASP A 1 84 ? -3.492 3.923 14.072 1.00 22.87 ? 385 ASP X N 1 |
| ATOM 475 C CA . ASP A 1 84 ? -4.527 4.658 14.800 1.00 24.23 ? 385 ASP X CA 1 |
| ATOM 476 C C . ASP A 1 84 ? -4.809 6.040 14.218 1.00 23.72 ? 385 ASP X C 1 |
| ATOM 477 O O . ASP A 1 84 ? -5.700 6.758 14.689 1.00 24.32 ? 385 ASP X O 1 |
| ATOM 478 C CB . ASP A 1 84 ? -4.181 4.742 16.286 1.00 25.06 ? 385 ASP X CB 1 |
| ATOM 479 C CG . ASP A 1 84 ? -4.312 3.390 16.981 1.00 27.87 ? 385 ASP X CG 1 |
| ATOM 480 O OD1 . ASP A 1 84 ? -5.416 2.790 16.940 1.00 31.98 ? 385 ASP X OD1 1 |
| ATOM 481 O OD2 . ASP A 1 84 ? -3.303 2.914 17.541 1.00 32.42 ? 385 ASP X OD2 1 |
| ATOM 482 N N . GLY A 1 85 ? -4.057 6.397 13.182 1.00 23.02 ? 386 GLY X N 1 |
| ATOM 483 C CA . GLY A 1 85 ? -4.240 7.667 12.496 1.00 22.24 ? 386 GLY X CA 1 |
| ATOM 484 C C . GLY A 1 85 ? -2.946 8.445 12.419 1.00 21.60 ? 386 GLY X C 1 |
| ATOM 485 O O . GLY A 1 85 ? -1.934 8.068 13.013 1.00 21.17 ? 386 GLY X O 1 |
| ATOM 486 N N . ASN A 1 86 ? -2.985 9.541 11.680 1.00 20.84 ? 387 ASN X N 1 |
| ATOM 487 C CA . ASN A 1 86 ? -1.817 10.373 11.564 1.00 20.47 ? 387 ASN X CA 1 |
| ATOM 488 C C . ASN A 1 86 ? -2.011 11.726 12.227 1.00 20.09 ? 387 ASN X C 1 |
| ATOM 489 O O . ASN A 1 86 ? -3.099 12.310 12.183 1.00 20.16 ? 387 ASN X O 1 |
| ATOM 490 C CB . ASN A 1 86 ? -1.442 10.591 10.111 1.00 21.20 ? 387 ASN X CB 1 |
| ATOM 491 C CG . ASN A 1 86 ? -0.278 11.534 9.984 1.00 22.48 ? 387 ASN X CG 1 |
| ATOM 492 O OD1 . ASN A 1 86 ? 0.833 11.200 10.403 1.00 22.90 ? 387 ASN X OD1 1 |
| ATOM 493 N ND2 . ASN A 1 86 ? -0.532 12.747 9.484 1.00 24.50 ? 387 ASN X ND2 1 |
| ATOM 494 N N . THR A 1 87 ? -0.948 12.216 12.848 1.00 18.77 ? 388 THR X N 1 |
| ATOM 495 C CA . THR A 1 87 ? -0.939 13.554 13.433 1.00 18.92 ? 388 THR X CA 1 |
| ATOM 496 C C . THR A 1 87 ? 0.396 14.216 13.104 1.00 17.64 ? 388 THR X C 1 |
| ATOM 497 O O . THR A 1 87 ? 1.452 13.770 13.570 1.00 16.74 ? 388 THR X O 1 |
| ATOM 498 C CB . THR A 1 87 ? -1.120 13.483 14.966 1.00 18.44 ? 388 THR X CB 1 |
| ATOM 499 O OG1 . THR A 1 87 ? -2.283 12.696 15.280 1.00 22.27 ? 388 THR X OG1 1 |
| ATOM 500 C CG2 . THR A 1 87 ? -1.281 14.891 15.573 1.00 21.36 ? 388 THR X CG2 1 |
| ATOM 501 N N . ASP A 1 88 ? 0.365 15.286 12.310 1.00 16.95 ? 389 ASP X N 1 |
| ATOM 502 C CA . ASP A 1 88 ? 1.593 16.052 12.036 1.00 16.29 ? 389 ASP X CA 1 |
| ATOM 503 C C . ASP A 1 88 ? 2.050 16.756 13.310 1.00 15.29 ? 389 ASP X C 1 |
| ATOM 504 O O . ASP A 1 88 ? 1.219 17.115 14.162 1.00 15.65 ? 389 ASP X O 1 |
| ATOM 505 C CB . ASP A 1 88 ? 1.388 17.066 10.922 1.00 17.30 ? 389 ASP X CB 1 |
| ATOM 506 C CG . ASP A 1 88 ? 1.004 16.420 9.617 1.00 19.81 ? 389 ASP X CG 1 |
| ATOM 507 O OD1 . ASP A 1 88 ? 1.546 15.334 9.301 1.00 20.88 ? 389 ASP X OD1 1 |
| ATOM 508 O OD2 . ASP A 1 88 ? 0.136 16.995 8.925 1.00 22.95 ? 389 ASP X OD2 1 |
| ATOM 509 N N . SER A 1 89 ? 3.359 16.968 13.415 1.00 14.00 ? 390 SER X N 1 |
| ATOM 510 C CA . SER A 1 89 ? 3.962 17.452 14.651 1.00 14.06 ? 390 SER X CA 1 |
| ATOM 511 C C . SER A 1 89 ? 4.494 18.867 14.525 1.00 13.74 ? 390 SER X C 1 |
| ATOM 512 O O . SER A 1 89 ? 5.214 19.166 13.591 1.00 13.41 ? 390 SER X O 1 |
| ATOM 513 C CB . SER A 1 89 ? 5.121 16.548 15.069 1.00 13.88 ? 390 SER X CB 1 |
| ATOM 514 O OG . SER A 1 89 ? 5.681 17.012 16.295 1.00 16.02 ? 390 SER X OG 1 |
| ATOM 515 N N . SER A 1 90 ? 4.132 19.721 15.478 1.00 13.55 ? 391 SER X N 1 |
| ATOM 516 C CA . SER A 1 90 ? 4.785 21.017 15.627 1.00 13.73 ? 391 SER X CA 1 |
| ATOM 517 C C . SER A 1 90 ? 5.801 20.986 16.773 1.00 13.98 ? 391 SER X C 1 |
| ATOM 518 O O . SER A 1 90 ? 6.291 22.027 17.207 1.00 14.62 ? 391 SER X O 1 |
| ATOM 519 C CB . SER A 1 90 ? 3.736 22.100 15.895 1.00 14.77 ? 391 SER X CB 1 |
| ATOM 520 O OG . SER A 1 90 ? 3.048 21.796 17.097 1.00 16.06 ? 391 SER X OG 1 |
| ATOM 521 N N . ALA A 1 91 ? 6.112 19.789 17.261 1.00 13.91 ? 392 ALA X N 1 |
| ATOM 522 C CA . ALA A 1 91 ? 6.931 19.632 18.467 1.00 13.94 ? 392 ALA X CA 1 |
| ATOM 523 C C . ALA A 1 91 ? 8.400 19.929 18.249 1.00 14.15 ? 392 ALA X C 1 |
| ATOM 524 O O . ALA A 1 91 ? 8.962 19.692 17.165 1.00 14.56 ? 392 ALA X O 1 |
| ATOM 525 C CB . ALA A 1 91 ? 6.759 18.226 19.066 1.00 14.63 ? 392 ALA X CB 1 |
| ATOM 526 N N . LEU A 1 92 ? 9.022 20.460 19.300 1.00 14.28 ? 393 LEU X N 1 |
| ATOM 527 C CA . LEU A 1 92 ? 10.462 20.565 19.393 1.00 14.42 ? 393 LEU X CA 1 |
| ATOM 528 C C . LEU A 1 92 ? 10.860 19.879 20.686 1.00 14.50 ? 393 LEU X C 1 |
| ATOM 529 O O . LEU A 1 92 ? 10.368 20.239 21.762 1.00 14.80 ? 393 LEU X O 1 |
| ATOM 530 C CB . LEU A 1 92 ? 10.923 22.030 19.402 1.00 14.69 ? 393 LEU X CB 1 |
| ATOM 531 C CG . LEU A 1 92 ? 12.432 22.207 19.604 1.00 14.80 ? 393 LEU X CG 1 |
| ATOM 532 C CD1 . LEU A 1 92 ? 13.225 21.710 18.395 1.00 14.30 ? 393 LEU X CD1 1 |
| ATOM 533 C CD2 . LEU A 1 92 ? 12.745 23.666 19.880 1.00 14.96 ? 393 LEU X CD2 1 |
| ATOM 534 N N . ASP A 1 93 ? 11.722 18.878 20.569 1.00 14.20 ? 394 ASP X N 1 |
| ATOM 535 C CA . ASP A 1 93 ? 12.194 18.144 21.741 1.00 15.14 ? 394 ASP X CA 1 |
| ATOM 536 C C . ASP A 1 93 ? 13.713 18.129 21.803 1.00 15.86 ? 394 ASP X C 1 |
| ATOM 537 O O . ASP A 1 93 ? 14.388 18.112 20.773 1.00 15.86 ? 394 ASP X O 1 |
| ATOM 538 C CB . ASP A 1 93 ? 11.609 16.742 21.736 1.00 15.38 ? 394 ASP X CB 1 |
| ATOM 539 C CG . ASP A 1 93 ? 10.101 16.769 21.781 1.00 17.70 ? 394 ASP X CG 1 |
| ATOM 540 O OD1 . ASP A 1 93 ? 9.544 16.994 22.880 1.00 19.29 ? 394 ASP X OD1 1 |
| ATOM 541 O OD2 . ASP A 1 93 ? 9.471 16.626 20.709 1.00 19.47 ? 394 ASP X OD2 1 |
| ATOM 542 N N . CYS A 1 94 ? 14.245 18.158 23.022 1.00 16.02 ? 395 CYS X N 1 |
| ATOM 543 C CA . CYS A 1 94 ? 15.677 18.318 23.205 1.00 16.42 ? 395 CYS X CA 1 |
| ATOM 544 C C . CYS A 1 94 ? 16.232 17.127 23.966 1.00 16.03 ? 395 CYS X C 1 |
| ATOM 545 O O . CYS A 1 94 ? 15.684 16.755 25.011 1.00 16.09 ? 395 CYS X O 1 |
| ATOM 546 C CB . CYS A 1 94 ? 15.951 19.625 23.960 1.00 17.25 ? 395 CYS X CB 1 |
| ATOM 547 S SG . CYS A 1 94 ? 17.710 20.005 24.205 1.00 21.31 ? 395 CYS X SG 1 |
| ATOM 548 N N . TYR A 1 95 ? 17.286 16.513 23.428 1.00 14.92 ? 396 TYR X N 1 |
| ATOM 549 C CA . TYR A 1 95 ? 17.943 15.388 24.083 1.00 14.57 ? 396 TYR X CA 1 |
| ATOM 550 C C . TYR A 1 95 ? 19.329 15.798 24.576 1.00 14.43 ? 396 TYR X C 1 |
| ATOM 551 O O . TYR A 1 95 ? 20.137 16.347 23.816 1.00 14.23 ? 396 TYR X O 1 |
| ATOM 552 C CB . TYR A 1 95 ? 18.073 14.212 23.120 1.00 13.84 ? 396 TYR X CB 1 |
| ATOM 553 C CG . TYR A 1 95 ? 18.842 13.033 23.674 1.00 13.76 ? 396 TYR X CG 1 |
| ATOM 554 C CD1 . TYR A 1 95 ? 18.222 12.120 24.523 1.00 12.41 ? 396 TYR X CD1 1 |
| ATOM 555 C CD2 . TYR A 1 95 ? 20.173 12.821 23.329 1.00 13.88 ? 396 TYR X CD2 1 |
| ATOM 556 C CE1 . TYR A 1 95 ? 18.918 11.017 25.036 1.00 13.71 ? 396 TYR X CE1 1 |
| ATOM 557 C CE2 . TYR A 1 95 ? 20.886 11.721 23.836 1.00 13.84 ? 396 TYR X CE2 1 |
| ATOM 558 C CZ . TYR A 1 95 ? 20.254 10.829 24.701 1.00 14.49 ? 396 TYR X CZ 1 |
| ATOM 559 O OH . TYR A 1 95 ? 20.940 9.739 25.204 1.00 14.82 ? 396 TYR X OH 1 |
| ATOM 560 N N . ASN A 1 96 ? 19.617 15.506 25.845 1.00 14.73 ? 397 ASN X N 1 |
| ATOM 561 C CA . ASN A 1 96 ? 20.937 15.783 26.379 1.00 14.76 ? 397 ASN X CA 1 |
| ATOM 562 C C . ASN A 1 96 ? 21.704 14.479 26.544 1.00 15.21 ? 397 ASN X C 1 |
| ATOM 563 O O . ASN A 1 96 ? 21.325 13.644 27.373 1.00 14.54 ? 397 ASN X O 1 |
| ATOM 564 C CB . ASN A 1 96 ? 20.840 16.522 27.718 1.00 14.89 ? 397 ASN X CB 1 |
| ATOM 565 C CG . ASN A 1 96 ? 22.204 16.970 28.243 1.00 15.79 ? 397 ASN X CG 1 |
| ATOM 566 O OD1 . ASN A 1 96 ? 23.258 16.557 27.739 1.00 17.62 ? 397 ASN X OD1 1 |
| ATOM 567 N ND2 . ASN A 1 96 ? 22.186 17.833 29.250 1.00 14.69 ? 397 ASN X ND2 1 |
| ATOM 568 N N . PRO A 1 97 ? 22.757 14.271 25.721 1.00 15.18 ? 398 PRO X N 1 |
| ATOM 569 C CA . PRO A 1 97 ? 23.504 13.023 25.818 1.00 15.91 ? 398 PRO X CA 1 |
| ATOM 570 C C . PRO A 1 97 ? 24.059 12.776 27.225 1.00 16.40 ? 398 PRO X C 1 |
| ATOM 571 O O . PRO A 1 97 ? 24.280 11.626 27.596 1.00 17.61 ? 398 PRO X O 1 |
| ATOM 572 C CB . PRO A 1 97 ? 24.668 13.224 24.845 1.00 16.43 ? 398 PRO X CB 1 |
| ATOM 573 C CG . PRO A 1 97 ? 24.182 14.243 23.884 1.00 15.86 ? 398 PRO X CG 1 |
| ATOM 574 C CD . PRO A 1 97 ? 23.292 15.155 24.672 1.00 15.65 ? 398 PRO X CD 1 |
| ATOM 575 N N . MET A 1 98 ? 24.287 13.852 27.978 1.00 16.37 ? 399 MET X N 1 |
| ATOM 576 C CA . MET A 1 98 ? 24.830 13.737 29.345 1.00 16.96 ? 399 MET X CA 1 |
| ATOM 577 C C . MET A 1 98 ? 23.838 13.200 30.377 1.00 16.62 ? 399 MET X C 1 |
| ATOM 578 O O . MET A 1 98 ? 24.253 12.711 31.434 1.00 16.46 ? 399 MET X O 1 |
| ATOM 579 C CB . MET A 1 98 ? 25.378 15.082 29.833 1.00 17.77 ? 399 MET X CB 1 |
| ATOM 580 C CG . MET A 1 98 ? 26.624 15.547 29.123 1.00 21.89 ? 399 MET X CG 1 |
| ATOM 581 S SD . MET A 1 98 ? 28.066 14.518 29.481 1.00 30.92 ? 399 MET X SD 1 |
| ATOM 582 C CE . MET A 1 98 ? 28.572 15.158 31.084 1.00 30.23 ? 399 MET X CE 1 |
| ATOM 583 N N . THR A 1 99 ? 22.544 13.318 30.081 1.00 15.77 ? 400 THR X N 1 |
| ATOM 584 C CA . THR A 1 99 ? 21.484 12.833 30.981 1.00 15.59 ? 400 THR X CA 1 |
| ATOM 585 C C . THR A 1 99 ? 20.691 11.664 30.386 1.00 15.15 ? 400 THR X C 1 |
| ATOM 586 O O . THR A 1 99 ? 19.957 10.976 31.105 1.00 14.79 ? 400 THR X O 1 |
| ATOM 587 C CB . THR A 1 99 ? 20.488 13.942 31.332 1.00 15.84 ? 400 THR X CB 1 |
| ATOM 588 O OG1 . THR A 1 99 ? 19.803 14.352 30.141 1.00 16.48 ? 400 THR X OG1 1 |
| ATOM 589 C CG2 . THR A 1 99 ? 21.201 15.149 31.970 1.00 16.05 ? 400 THR X CG2 1 |
| ATOM 590 N N . ASN A 1 100 ? 20.818 11.456 29.073 1.00 14.85 ? 401 ASN X N 1 |
| ATOM 591 C CA . ASN A 1 100 ? 20.024 10.459 28.355 1.00 15.53 ? 401 ASN X CA 1 |
| ATOM 592 C C . ASN A 1 100 ? 18.526 10.681 28.587 1.00 15.50 ? 401 ASN X C 1 |
| ATOM 593 O O . ASN A 1 100 ? 17.752 9.733 28.767 1.00 16.62 ? 401 ASN X O 1 |
| ATOM 594 C CB . ASN A 1 100 ? 20.454 9.019 28.716 1.00 15.11 ? 401 ASN X CB 1 |
| ATOM 595 C CG . ASN A 1 100 ? 19.748 7.963 27.864 1.00 16.38 ? 401 ASN X CG 1 |
| ATOM 596 O OD1 . ASN A 1 100 ? 19.495 8.173 26.676 1.00 15.66 ? 401 ASN X OD1 1 |
| ATOM 597 N ND2 . ASN A 1 100 ? 19.409 6.837 28.474 1.00 18.43 ? 401 ASN X ND2 1 |
| ATOM 598 N N . GLN A 1 101 ? 18.128 11.950 28.581 1.00 16.07 ? 402 GLN X N 1 |
| ATOM 599 C CA . GLN A 1 101 ? 16.732 12.317 28.751 1.00 17.36 ? 402 GLN X CA 1 |
| ATOM 600 C C . GLN A 1 101 ? 16.300 13.270 27.648 1.00 16.54 ? 402 GLN X C 1 |
| ATOM 601 O O . GLN A 1 101 ? 17.063 14.156 27.244 1.00 15.49 ? 402 GLN X O 1 |
| ATOM 602 C CB . GLN A 1 101 ? 16.520 13.039 30.080 1.00 17.56 ? 402 GLN X CB 1 |
| ATOM 603 C CG . GLN A 1 101 ? 16.840 12.269 31.347 1.00 20.40 ? 402 GLN X CG 1 |
| ATOM 604 C CD . GLN A 1 101 ? 16.448 13.058 32.589 1.00 20.90 ? 402 GLN X CD 1 |
| ATOM 605 O OE1 . GLN A 1 101 ? 15.528 13.887 32.557 1.00 27.50 ? 402 GLN X OE1 1 |
| ATOM 606 N NE2 . GLN A 1 101 ? 17.142 12.819 33.677 1.00 19.79 ? 402 GLN X NE2 1 |
| ATOM 607 N N . TRP A 1 102 ? 15.059 13.093 27.198 1.00 16.90 ? 403 TRP X N 1 |
| ATOM 608 C CA . TRP A 1 102 ? 14.379 14.060 26.337 1.00 17.18 ? 403 TRP X CA 1 |
| ATOM 609 C C . TRP A 1 102 ? 13.598 15.075 27.157 1.00 17.83 ? 403 TRP X C 1 |
| ATOM 610 O O . TRP A 1 102 ? 12.992 14.737 28.178 1.00 18.58 ? 403 TRP X O 1 |
| ATOM 611 C CB . TRP A 1 102 ? 13.400 13.349 25.399 1.00 16.64 ? 403 TRP X CB 1 |
| ATOM 612 C CG . TRP A 1 102 ? 14.042 12.537 24.334 1.00 15.94 ? 403 TRP X CG 1 |
| ATOM 613 C CD1 . TRP A 1 102 ? 14.314 11.196 24.374 1.00 15.42 ? 403 TRP X CD1 1 |
| ATOM 614 C CD2 . TRP A 1 102 ? 14.505 13.006 23.066 1.00 16.12 ? 403 TRP X CD2 1 |
| ATOM 615 N NE1 . TRP A 1 102 ? 14.911 10.799 23.202 1.00 15.63 ? 403 TRP X NE1 1 |
| ATOM 616 C CE2 . TRP A 1 102 ? 15.044 11.893 22.383 1.00 15.86 ? 403 TRP X CE2 1 |
| ATOM 617 C CE3 . TRP A 1 102 ? 14.507 14.258 22.436 1.00 15.34 ? 403 TRP X CE3 1 |
| ATOM 618 C CZ2 . TRP A 1 102 ? 15.581 11.991 21.085 1.00 17.48 ? 403 TRP X CZ2 1 |
| ATOM 619 C CZ3 . TRP A 1 102 ? 15.056 14.359 21.148 1.00 15.84 ? 403 TRP X CZ3 1 |
| ATOM 620 C CH2 . TRP A 1 102 ? 15.585 13.234 20.494 1.00 16.15 ? 403 TRP X CH2 1 |
| ATOM 621 N N . SER A 1 103 ? 13.596 16.316 26.692 1.00 18.10 ? 404 SER X N 1 |
| ATOM 622 C CA . SER A 1 103 ? 12.823 17.369 27.335 1.00 18.83 ? 404 SER X CA 1 |
| ATOM 623 C C . SER A 1 103 ? 12.026 18.106 26.273 1.00 19.00 ? 404 SER X C 1 |
| ATOM 624 O O . SER A 1 103 ? 12.598 18.504 25.249 1.00 18.77 ? 404 SER X O 1 |
| ATOM 625 C CB . SER A 1 103 ? 13.750 18.346 28.048 1.00 19.37 ? 404 SER X CB 1 |
| ATOM 626 O OG . SER A 1 103 ? 14.413 17.692 29.113 1.00 21.30 ? 404 SER X OG 1 |
| ATOM 627 N N . PRO A 1 104 ? 10.711 18.281 26.496 1.00 19.08 ? 405 PRO X N 1 |
| ATOM 628 C CA . PRO A 1 104 ? 9.932 19.090 25.554 1.00 19.38 ? 405 PRO X CA 1 |
| ATOM 629 C C . PRO A 1 104 ? 10.367 20.546 25.581 1.00 19.25 ? 405 PRO X C 1 |
| ATOM 630 O O . PRO A 1 104 ? 10.761 21.072 26.638 1.00 19.86 ? 405 PRO X O 1 |
| ATOM 631 C CB . PRO A 1 104 ? 8.490 18.974 26.075 1.00 19.73 ? 405 PRO X CB 1 |
| ATOM 632 C CG . PRO A 1 104 ? 8.500 17.777 27.002 1.00 21.14 ? 405 PRO X CG 1 |
| ATOM 633 C CD . PRO A 1 104 ? 9.878 17.736 27.588 1.00 19.81 ? 405 PRO X CD 1 |
| ATOM 634 N N . CYS A 1 105 ? 10.301 21.189 24.422 1.00 18.65 ? 406 CYS X N 1 |
| ATOM 635 C CA . CYS A 1 105 ? 10.532 22.627 24.305 1.00 19.02 ? 406 CYS X CA 1 |
| ATOM 636 C C . CYS A 1 105 ? 9.263 23.254 23.749 1.00 18.39 ? 406 CYS X C 1 |
| ATOM 637 O O . CYS A 1 105 ? 8.274 22.536 23.516 1.00 18.76 ? 406 CYS X O 1 |
| ATOM 638 C CB . CYS A 1 105 ? 11.701 22.892 23.361 1.00 21.07 ? 406 CYS X CB 1 |
| ATOM 639 S SG . CYS A 1 105 ? 13.265 22.169 23.834 1.00 21.38 ? 406 CYS X SG 1 |
| ATOM 640 N N . ALA A 1 106 ? 9.291 24.570 23.515 1.00 17.72 ? 407 ALA X N 1 |
| ATOM 641 C CA . ALA A 1 106 ? 8.156 25.298 22.933 1.00 17.26 ? 407 ALA X CA 1 |
| ATOM 642 C C . ALA A 1 106 ? 7.874 24.784 21.518 1.00 16.87 ? 407 ALA X C 1 |
| ATOM 643 O O . ALA A 1 106 ? 8.823 24.565 20.758 1.00 16.58 ? 407 ALA X O 1 |
| ATOM 644 C CB . ALA A 1 106 ? 8.434 26.796 22.910 1.00 17.67 ? 407 ALA X CB 1 |
| ATOM 645 N N . PRO A 1 107 ? 6.586 24.565 21.170 1.00 16.69 ? 408 PRO X N 1 |
| ATOM 646 C CA . PRO A 1 107 ? 6.247 24.099 19.821 1.00 16.59 ? 408 PRO X CA 1 |
| ATOM 647 C C . PRO A 1 107 ? 6.297 25.205 18.781 1.00 16.26 ? 408 PRO X C 1 |
| ATOM 648 O O . PRO A 1 107 ? 6.213 26.404 19.110 1.00 16.11 ? 408 PRO X O 1 |
| ATOM 649 C CB . PRO A 1 107 ? 4.814 23.589 19.973 1.00 17.08 ? 408 PRO X CB 1 |
| ATOM 650 C CG . PRO A 1 107 ? 4.238 24.452 21.035 1.00 17.72 ? 408 PRO X CG 1 |
| ATOM 651 C CD . PRO A 1 107 ? 5.380 24.725 22.005 1.00 17.89 ? 408 PRO X CD 1 |
| ATOM 652 N N . MET A 1 108 ? 6.454 24.798 17.524 1.00 15.47 ? 409 MET X N 1 |
| ATOM 653 C CA . MET A 1 108 ? 6.412 25.734 16.408 1.00 15.39 ? 409 MET X CA 1 |
| ATOM 654 C C . MET A 1 108 ? 5.010 26.292 16.192 1.00 15.09 ? 409 MET X C 1 |
| ATOM 655 O O . MET A 1 108 ? 4.031 25.783 16.746 1.00 15.35 ? 409 MET X O 1 |
| ATOM 656 C CB . MET A 1 108 ? 6.887 25.031 15.134 1.00 14.89 ? 409 MET X CB 1 |
| ATOM 657 C CG . MET A 1 108 ? 8.309 24.537 15.230 1.00 15.46 ? 409 MET X CG 1 |
| ATOM 658 S SD . MET A 1 108 ? 8.860 23.714 13.735 1.00 15.52 ? 409 MET X SD 1 |
| ATOM 659 C CE . MET A 1 108 ? 7.874 22.214 13.792 1.00 14.81 ? 409 MET X CE 1 |
| ATOM 660 N N . SER A 1 109 ? 4.912 27.325 15.356 1.00 15.40 ? 410 SER X N 1 |
| ATOM 661 C CA . SER A 1 109 ? 3.619 27.932 15.034 1.00 15.78 ? 410 SER X CA 1 |
| ATOM 662 C C . SER A 1 109 ? 2.652 26.985 14.312 1.00 15.66 ? 410 SER X C 1 |
| ATOM 663 O O . SER A 1 109 ? 1.432 27.153 14.399 1.00 16.50 ? 410 SER X O 1 |
| ATOM 664 C CB . SER A 1 109 ? 3.813 29.167 14.154 1.00 15.76 ? 410 SER X CB 1 |
| ATOM 665 O OG . SER A 1 109 ? 4.309 28.782 12.883 1.00 16.81 ? 410 SER X OG 1 |
| ATOM 666 N N . VAL A 1 110 ? 3.222 26.019 13.588 1.00 15.12 ? 411 VAL X N 1 |
| ATOM 667 C CA A VAL A 1 110 ? 2.459 25.103 12.731 0.50 14.47 ? 411 VAL X CA 1 |
| ATOM 668 C CA B VAL A 1 110 ? 2.469 25.123 12.720 0.50 14.86 ? 411 VAL X CA 1 |
| ATOM 669 C C . VAL A 1 110 ? 3.149 23.746 12.711 1.00 14.34 ? 411 VAL X C 1 |
| ATOM 670 O O . VAL A 1 110 ? 4.362 23.673 12.900 1.00 14.56 ? 411 VAL X O 1 |
| ATOM 671 C CB A VAL A 1 110 ? 2.362 25.595 11.257 0.50 14.91 ? 411 VAL X CB 1 |
| ATOM 672 C CB B VAL A 1 110 ? 2.409 25.717 11.286 0.50 15.42 ? 411 VAL X CB 1 |
| ATOM 673 C CG1 A VAL A 1 110 ? 1.404 26.771 11.124 0.50 13.75 ? 411 VAL X CG1 1 |
| ATOM 674 C CG1 B VAL A 1 110 ? 3.746 25.576 10.561 0.50 14.86 ? 411 VAL X CG1 1 |
| ATOM 675 C CG2 A VAL A 1 110 ? 3.735 25.944 10.703 0.50 13.96 ? 411 VAL X CG2 1 |
| ATOM 676 C CG2 B VAL A 1 110 ? 1.295 25.107 10.488 0.50 15.93 ? 411 VAL X CG2 1 |
| ATOM 677 N N . PRO A 1 111 ? 2.371 22.657 12.508 1.00 13.80 ? 412 PRO X N 1 |
| ATOM 678 C CA . PRO A 1 111 ? 3.041 21.364 12.294 1.00 13.68 ? 412 PRO X CA 1 |
| ATOM 679 C C . PRO A 1 111 ? 3.833 21.361 10.993 1.00 13.52 ? 412 PRO X C 1 |
| ATOM 680 O O . PRO A 1 111 ? 3.417 22.004 10.010 1.00 13.93 ? 412 PRO X O 1 |
| ATOM 681 C CB . PRO A 1 111 ? 1.875 20.365 12.198 1.00 14.04 ? 412 PRO X CB 1 |
| ATOM 682 C CG . PRO A 1 111 ? 0.733 21.038 12.931 1.00 14.10 ? 412 PRO X CG 1 |
| ATOM 683 C CD . PRO A 1 111 ? 0.898 22.500 12.559 1.00 14.38 ? 412 PRO X CD 1 |
| ATOM 684 N N . ARG A 1 112 ? 4.974 20.661 10.990 1.00 13.26 ? 413 ARG X N 1 |
| ATOM 685 C CA . ARG A 1 112 ? 5.831 20.606 9.809 1.00 13.25 ? 413 ARG X CA 1 |
| ATOM 686 C C . ARG A 1 112 ? 6.354 19.201 9.579 1.00 12.81 ? 413 ARG X C 1 |
| ATOM 687 O O . ARG A 1 112 ? 7.414 18.845 10.090 1.00 13.31 ? 413 ARG X O 1 |
| ATOM 688 C CB . ARG A 1 112 ? 7.000 21.570 9.944 1.00 13.14 ? 413 ARG X CB 1 |
| ATOM 689 C CG . ARG A 1 112 ? 6.565 23.031 10.024 1.00 13.79 ? 413 ARG X CG 1 |
| ATOM 690 C CD . ARG A 1 112 ? 7.796 23.918 10.186 1.00 13.64 ? 413 ARG X CD 1 |
| ATOM 691 N NE . ARG A 1 112 ? 7.439 25.318 10.424 1.00 14.31 ? 413 ARG X NE 1 |
| ATOM 692 C CZ . ARG A 1 112 ? 7.201 26.200 9.456 1.00 15.26 ? 413 ARG X CZ 1 |
| ATOM 693 N NH1 . ARG A 1 112 ? 7.287 25.828 8.172 1.00 14.78 ? 413 ARG X NH1 1 |
| ATOM 694 N NH2 . ARG A 1 112 ? 6.876 27.458 9.773 1.00 15.44 ? 413 ARG X NH2 1 |
| ATOM 695 N N . ASN A 1 113 ? 5.602 18.414 8.817 1.00 12.48 ? 414 ASN X N 1 |
| ATOM 696 C CA . ASN A 1 113 ? 6.070 17.096 8.388 1.00 12.42 ? 414 ASN X CA 1 |
| ATOM 697 C C . ASN A 1 113 ? 7.038 17.283 7.223 1.00 12.51 ? 414 ASN X C 1 |
| ATOM 698 O O . ASN A 1 113 ? 6.790 18.117 6.354 1.00 12.60 ? 414 ASN X O 1 |
| ATOM 699 C CB . ASN A 1 113 ? 4.870 16.248 7.938 1.00 12.87 ? 414 ASN X CB 1 |
| ATOM 700 C CG . ASN A 1 113 ? 5.274 14.915 7.367 1.00 14.58 ? 414 ASN X CG 1 |
| ATOM 701 O OD1 . ASN A 1 113 ? 6.095 14.217 7.931 1.00 17.08 ? 414 ASN X OD1 1 |
| ATOM 702 N ND2 . ASN A 1 113 ? 4.685 14.567 6.225 1.00 20.22 ? 414 ASN X ND2 1 |
| ATOM 703 N N . ARG A 1 114 ? 8.103 16.480 7.162 1.00 12.41 ? 415 ARG X N 1 |
| ATOM 704 C CA . ARG A 1 114 ? 9.091 16.584 6.067 1.00 11.96 ? 415 ARG X CA 1 |
| ATOM 705 C C . ARG A 1 114 ? 9.709 17.996 6.025 1.00 13.03 ? 415 ARG X C 1 |
| ATOM 706 O O . ARG A 1 114 ? 9.931 18.616 4.975 1.00 12.40 ? 415 ARG X O 1 |
| ATOM 707 C CB . ARG A 1 114 ? 8.498 16.130 4.731 1.00 12.04 ? 415 ARG X CB 1 |
| ATOM 708 C CG . ARG A 1 114 ? 8.033 14.680 4.744 1.00 12.83 ? 415 ARG X CG 1 |
| ATOM 709 C CD . ARG A 1 114 ? 7.681 14.208 3.345 1.00 14.16 ? 415 ARG X CD 1 |
| ATOM 710 N NE . ARG A 1 114 ? 8.921 14.045 2.573 1.00 15.53 ? 415 ARG X NE 1 |
| ATOM 711 C CZ . ARG A 1 114 ? 8.982 14.016 1.241 1.00 16.21 ? 415 ARG X CZ 1 |
| ATOM 712 N NH1 . ARG A 1 114 ? 7.881 14.139 0.507 1.00 17.01 ? 415 ARG X NH1 1 |
| ATOM 713 N NH2 . ARG A 1 114 ? 10.162 13.878 0.651 1.00 18.84 ? 415 ARG X NH2 1 |
| ATOM 714 N N . ILE A 1 115 ? 10.005 18.460 7.230 1.00 13.21 ? 416 ILE X N 1 |
| ATOM 715 C CA . ILE A 1 115 ? 10.676 19.702 7.535 1.00 13.28 ? 416 ILE X CA 1 |
| ATOM 716 C C . ILE A 1 115 ? 12.174 19.647 7.184 1.00 13.41 ? 416 ILE X C 1 |
| ATOM 717 O O . ILE A 1 115 ? 12.766 18.545 7.122 1.00 13.19 ? 416 ILE X O 1 |
| ATOM 718 C CB . ILE A 1 115 ? 10.533 19.915 9.049 1.00 13.34 ? 416 ILE X CB 1 |
| ATOM 719 C CG1 . ILE A 1 115 ? 10.931 21.331 9.454 1.00 14.70 ? 416 ILE X CG1 1 |
| ATOM 720 C CG2 . ILE A 1 115 ? 11.352 18.857 9.812 1.00 14.22 ? 416 ILE X CG2 1 |
| ATOM 721 C CD1 . ILE A 1 115 ? 10.736 21.570 10.936 1.00 15.36 ? 416 ILE X CD1 1 |
| ATOM 722 N N . GLY A 1 116 ? 12.774 20.826 6.960 1.00 13.01 ? 417 GLY X N 1 |
| ATOM 723 C CA . GLY A 1 116 ? 14.238 20.949 6.904 1.00 12.94 ? 417 GLY X CA 1 |
| ATOM 724 C C . GLY A 1 116 ? 14.671 21.944 7.968 1.00 12.83 ? 417 GLY X C 1 |
| ATOM 725 O O . GLY A 1 116 ? 13.940 22.882 8.281 1.00 12.51 ? 417 GLY X O 1 |
| ATOM 726 N N . VAL A 1 117 ? 15.827 21.709 8.576 1.00 12.55 ? 418 VAL X N 1 |
| ATOM 727 C CA . VAL A 1 117 ? 16.336 22.672 9.551 1.00 13.85 ? 418 VAL X CA 1 |
| ATOM 728 C C . VAL A 1 117 ? 17.792 23.079 9.307 1.00 13.64 ? 418 VAL X C 1 |
| ATOM 729 O O . VAL A 1 117 ? 18.555 22.357 8.675 1.00 14.15 ? 418 VAL X O 1 |
| ATOM 730 C CB . VAL A 1 117 ? 16.193 22.179 11.005 1.00 14.62 ? 418 VAL X CB 1 |
| ATOM 731 C CG1 . VAL A 1 117 ? 14.727 21.818 11.308 1.00 15.67 ? 418 VAL X CG1 1 |
| ATOM 732 C CG2 . VAL A 1 117 ? 17.131 21.005 11.293 1.00 16.38 ? 418 VAL X CG2 1 |
| ATOM 733 N N . GLY A 1 118 ? 18.149 24.258 9.820 1.00 13.46 ? 419 GLY X N 1 |
| ATOM 734 C CA . GLY A 1 118 ? 19.531 24.740 9.799 1.00 14.19 ? 419 GLY X CA 1 |
| ATOM 735 C C . GLY A 1 118 ? 19.775 25.567 11.051 1.00 14.04 ? 419 GLY X C 1 |
| ATOM 736 O O . GLY A 1 118 ? 18.825 26.097 11.650 1.00 15.54 ? 419 GLY X O 1 |
| ATOM 737 N N . VAL A 1 119 ? 21.033 25.657 11.470 1.00 14.04 ? 420 VAL X N 1 |
| ATOM 738 C CA . VAL A 1 119 ? 21.413 26.444 12.643 1.00 14.74 ? 420 VAL X CA 1 |
| ATOM 739 C C . VAL A 1 119 ? 22.301 27.630 12.229 1.00 15.09 ? 420 VAL X C 1 |
| ATOM 740 O O . VAL A 1 119 ? 23.291 27.463 11.525 1.00 15.42 ? 420 VAL X O 1 |
| ATOM 741 C CB . VAL A 1 119 ? 22.137 25.545 13.677 1.00 14.37 ? 420 VAL X CB 1 |
| ATOM 742 C CG1 . VAL A 1 119 ? 22.568 26.354 14.890 1.00 15.10 ? 420 VAL X CG1 1 |
| ATOM 743 C CG2 . VAL A 1 119 ? 21.216 24.393 14.119 1.00 15.55 ? 420 VAL X CG2 1 |
| ATOM 744 N N . ILE A 1 120 ? 21.928 28.835 12.654 1.00 15.44 ? 421 ILE X N 1 |
| ATOM 745 C CA . ILE A 1 120 ? 22.795 30.008 12.478 1.00 16.57 ? 421 ILE X CA 1 |
| ATOM 746 C C . ILE A 1 120 ? 22.843 30.768 13.800 1.00 17.10 ? 421 ILE X C 1 |
| ATOM 747 O O . ILE A 1 120 ? 21.800 31.041 14.387 1.00 17.74 ? 421 ILE X O 1 |
| ATOM 748 C CB . ILE A 1 120 ? 22.285 30.975 11.392 1.00 16.52 ? 421 ILE X CB 1 |
| ATOM 749 C CG1 . ILE A 1 120 ? 22.059 30.249 10.066 1.00 17.11 ? 421 ILE X CG1 1 |
| ATOM 750 C CG2 . ILE A 1 120 ? 23.285 32.117 11.182 1.00 16.83 ? 421 ILE X CG2 1 |
| ATOM 751 C CD1 . ILE A 1 120 ? 21.389 31.113 9.010 1.00 17.38 ? 421 ILE X CD1 1 |
| ATOM 752 N N . ASP A 1 121 ? 24.054 31.089 14.261 1.00 18.42 ? 422 ASP X N 1 |
| ATOM 753 C CA . ASP A 1 121 ? 24.261 31.879 15.485 1.00 19.15 ? 422 ASP X CA 1 |
| ATOM 754 C C . ASP A 1 121 ? 23.520 31.267 16.668 1.00 18.80 ? 422 ASP X C 1 |
| ATOM 755 O O . ASP A 1 121 ? 22.958 31.987 17.506 1.00 18.95 ? 422 ASP X O 1 |
| ATOM 756 C CB . ASP A 1 121 ? 23.825 33.344 15.312 1.00 19.95 ? 422 ASP X CB 1 |
| ATOM 757 C CG . ASP A 1 121 ? 24.610 34.082 14.235 1.00 22.41 ? 422 ASP X CG 1 |
| ATOM 758 O OD1 . ASP A 1 121 ? 25.723 33.647 13.861 1.00 26.55 ? 422 ASP X OD1 1 |
| ATOM 759 O OD2 . ASP A 1 121 ? 24.096 35.114 13.757 1.00 26.60 ? 422 ASP X OD2 1 |
| ATOM 760 N N . GLY A 1 122 ? 23.509 29.935 16.723 1.00 17.74 ? 423 GLY X N 1 |
| ATOM 761 C CA . GLY A 1 122 ? 22.869 29.217 17.828 1.00 17.46 ? 423 GLY X CA 1 |
| ATOM 762 C C . GLY A 1 122 ? 21.345 29.237 17.856 1.00 16.83 ? 423 GLY X C 1 |
| ATOM 763 O O . GLY A 1 122 ? 20.741 28.934 18.887 1.00 17.02 ? 423 GLY X O 1 |
| ATOM 764 N N . HIS A 1 123 ? 20.724 29.606 16.733 1.00 16.29 ? 424 HIS X N 1 |
| ATOM 765 C CA . HIS A 1 123 ? 19.271 29.583 16.582 1.00 16.30 ? 424 HIS X CA 1 |
| ATOM 766 C C . HIS A 1 123 ? 18.904 28.534 15.552 1.00 15.63 ? 424 HIS X C 1 |
| ATOM 767 O O . HIS A 1 123 ? 19.631 28.345 14.576 1.00 16.40 ? 424 HIS X O 1 |
| ATOM 768 C CB . HIS A 1 123 ? 18.732 30.941 16.104 1.00 16.95 ? 424 HIS X CB 1 |
| ATOM 769 C CG . HIS A 1 123 ? 19.046 32.088 17.022 1.00 19.46 ? 424 HIS X CG 1 |
| ATOM 770 N ND1 . HIS A 1 123 ? 19.519 31.915 18.306 1.00 24.14 ? 424 HIS X ND1 1 |
| ATOM 771 C CD2 . HIS A 1 123 ? 18.946 33.423 16.835 1.00 23.95 ? 424 HIS X CD2 1 |
| ATOM 772 C CE1 . HIS A 1 123 ? 19.707 33.098 18.868 1.00 24.51 ? 424 HIS X CE1 1 |
| ATOM 773 N NE2 . HIS A 1 123 ? 19.364 34.029 17.997 1.00 25.28 ? 424 HIS X NE2 1 |
| ATOM 774 N N . ILE A 1 124 ? 17.774 27.866 15.768 1.00 14.40 ? 425 ILE X N 1 |
| ATOM 775 C CA . ILE A 1 124 ? 17.323 26.821 14.843 1.00 14.24 ? 425 ILE X CA 1 |
| ATOM 776 C C . ILE A 1 124 ? 16.298 27.410 13.893 1.00 14.07 ? 425 ILE X C 1 |
| ATOM 777 O O . ILE A 1 124 ? 15.279 27.966 14.327 1.00 15.11 ? 425 ILE X O 1 |
| ATOM 778 C CB . ILE A 1 124 ? 16.649 25.663 15.603 1.00 13.67 ? 425 ILE X CB 1 |
| ATOM 779 C CG1 . ILE A 1 124 ? 17.590 25.085 16.680 1.00 14.46 ? 425 ILE X CG1 1 |
| ATOM 780 C CG2 . ILE A 1 124 ? 16.191 24.574 14.645 1.00 14.53 ? 425 ILE X CG2 1 |
| ATOM 781 C CD1 . ILE A 1 124 ? 16.935 24.021 17.550 1.00 14.79 ? 425 ILE X CD1 1 |
| ATOM 782 N N . TYR A 1 125 ? 16.558 27.287 12.598 1.00 13.71 ? 426 TYR X N 1 |
| ATOM 783 C CA . TYR A 1 125 ? 15.569 27.665 11.590 1.00 13.34 ? 426 TYR X CA 1 |
| ATOM 784 C C . TYR A 1 125 ? 14.802 26.425 11.135 1.00 13.20 ? 426 TYR X C 1 |
| ATOM 785 O O . TYR A 1 125 ? 15.421 25.432 10.723 1.00 13.85 ? 426 TYR X O 1 |
| ATOM 786 C CB . TYR A 1 125 ? 16.238 28.316 10.382 1.00 14.07 ? 426 TYR X CB 1 |
| ATOM 787 C CG . TYR A 1 125 ? 16.745 29.710 10.648 1.00 13.99 ? 426 TYR X CG 1 |
| ATOM 788 C CD1 . TYR A 1 125 ? 17.939 29.927 11.335 1.00 15.17 ? 426 TYR X CD1 1 |
| ATOM 789 C CD2 . TYR A 1 125 ? 16.013 30.822 10.217 1.00 14.31 ? 426 TYR X CD2 1 |
| ATOM 790 C CE1 . TYR A 1 125 ? 18.397 31.228 11.591 1.00 16.77 ? 426 TYR X CE1 1 |
| ATOM 791 C CE2 . TYR A 1 125 ? 16.464 32.125 10.470 1.00 15.33 ? 426 TYR X CE2 1 |
| ATOM 792 C CZ . TYR A 1 125 ? 17.657 32.311 11.149 1.00 16.42 ? 426 TYR X CZ 1 |
| ATOM 793 O OH . TYR A 1 125 ? 18.121 33.591 11.401 1.00 18.14 ? 426 TYR X OH 1 |
| ATOM 794 N N . ALA A 1 126 ? 13.473 26.485 11.234 1.00 12.40 ? 427 ALA X N 1 |
| ATOM 795 C CA . ALA A 1 126 ? 12.565 25.430 10.773 1.00 12.87 ? 427 ALA X CA 1 |
| ATOM 796 C C . ALA A 1 126 ? 11.968 25.908 9.446 1.00 13.50 ? 427 ALA X C 1 |
| ATOM 797 O O . ALA A 1 126 ? 11.374 26.985 9.399 1.00 13.69 ? 427 ALA X O 1 |
| ATOM 798 C CB . ALA A 1 126 ? 11.461 25.181 11.802 1.00 13.03 ? 427 ALA X CB 1 |
| ATOM 799 N N . VAL A 1 127 ? 12.162 25.126 8.380 1.00 12.64 ? 428 VAL X N 1 |
| ATOM 800 C CA . VAL A 1 127 ? 11.892 25.542 7.019 1.00 13.30 ? 428 VAL X CA 1 |
| ATOM 801 C C . VAL A 1 127 ? 10.887 24.594 6.366 1.00 12.97 ? 428 VAL X C 1 |
| ATOM 802 O O . VAL A 1 127 ? 11.139 23.393 6.276 1.00 13.69 ? 428 VAL X O 1 |
| ATOM 803 C CB . VAL A 1 127 ? 13.207 25.498 6.173 1.00 14.22 ? 428 VAL X CB 1 |
| ATOM 804 C CG1 . VAL A 1 127 ? 12.924 25.871 4.729 1.00 14.96 ? 428 VAL X CG1 1 |
| ATOM 805 C CG2 . VAL A 1 127 ? 14.271 26.417 6.765 1.00 14.64 ? 428 VAL X CG2 1 |
| ATOM 806 N N . GLY A 1 128 ? 9.784 25.147 5.862 1.00 12.89 ? 429 GLY X N 1 |
| ATOM 807 C CA . GLY A 1 128 ? 8.851 24.394 5.015 1.00 13.06 ? 429 GLY X CA 1 |
| ATOM 808 C C . GLY A 1 128 ? 8.172 23.249 5.737 1.00 12.96 ? 429 GLY X C 1 |
| ATOM 809 O O . GLY A 1 128 ? 7.851 23.335 6.921 1.00 13.23 ? 429 GLY X O 1 |
| ATOM 810 N N . GLY A 1 129 ? 8.017 22.144 5.026 1.00 12.88 ? 430 GLY X N 1 |
| ATOM 811 C CA . GLY A 1 129 ? 7.269 21.002 5.557 1.00 12.97 ? 430 GLY X CA 1 |
| ATOM 812 C C . GLY A 1 129 ? 5.777 21.144 5.299 1.00 14.09 ? 430 GLY X C 1 |
| ATOM 813 O O . GLY A 1 129 ? 5.326 22.140 4.721 1.00 15.12 ? 430 GLY X O 1 |
| ATOM 814 N N . SER A 1 130 ? 5.007 20.156 5.737 1.00 14.37 ? 431 SER X N 1 |
| ATOM 815 C CA . SER A 1 130 ? 3.572 20.164 5.473 1.00 14.58 ? 431 SER X CA 1 |
| ATOM 816 C C . SER A 1 130 ? 2.738 19.990 6.738 1.00 13.94 ? 431 SER X C 1 |
| ATOM 817 O O . SER A 1 130 ? 3.212 19.492 7.757 1.00 13.76 ? 431 SER X O 1 |
| ATOM 818 C CB . SER A 1 130 ? 3.206 19.061 4.475 1.00 14.97 ? 431 SER X CB 1 |
| ATOM 819 O OG . SER A 1 130 ? 3.489 17.784 5.009 1.00 16.87 ? 431 SER X OG 1 |
| ATOM 820 N N . HIS A 1 131 ? 1.487 20.423 6.643 1.00 14.01 ? 432 HIS X N 1 |
| ATOM 821 C CA . HIS A 1 131 ? 0.503 20.172 7.689 1.00 15.05 ? 432 HIS X CA 1 |
| ATOM 822 C C . HIS A 1 131 ? -0.740 19.728 6.931 1.00 15.40 ? 432 HIS X C 1 |
| ATOM 823 O O . HIS A 1 131 ? -1.408 20.556 6.285 1.00 15.23 ? 432 HIS X O 1 |
| ATOM 824 C CB . HIS A 1 131 ? 0.231 21.421 8.526 1.00 16.09 ? 432 HIS X CB 1 |
| ATOM 825 C CG . HIS A 1 131 ? -0.913 21.253 9.472 1.00 17.30 ? 432 HIS X CG 1 |
| ATOM 826 N ND1 . HIS A 1 131 ? -1.718 22.301 9.862 1.00 20.20 ? 432 HIS X ND1 1 |
| ATOM 827 C CD2 . HIS A 1 131 ? -1.405 20.148 10.084 1.00 19.16 ? 432 HIS X CD2 1 |
| ATOM 828 C CE1 . HIS A 1 131 ? -2.641 21.853 10.697 1.00 19.52 ? 432 HIS X CE1 1 |
| ATOM 829 N NE2 . HIS A 1 131 ? -2.482 20.550 10.840 1.00 19.98 ? 432 HIS X NE2 1 |
| ATOM 830 N N . GLY A 1 132 ? -1.021 18.429 6.963 1.00 15.59 ? 433 GLY X N 1 |
| ATOM 831 C CA . GLY A 1 132 ? -2.045 17.861 6.081 1.00 16.48 ? 433 GLY X CA 1 |
| ATOM 832 C C . GLY A 1 132 ? -1.676 18.123 4.633 1.00 17.76 ? 433 GLY X C 1 |
| ATOM 833 O O . GLY A 1 132 ? -0.563 17.800 4.201 1.00 18.72 ? 433 GLY X O 1 |
| ATOM 834 N N . CYS A 1 133 ? -2.578 18.771 3.900 1.00 18.57 ? 434 CYS X N 1 |
| ATOM 835 C CA A CYS A 1 133 ? -2.329 19.047 2.487 0.50 18.77 ? 434 CYS X CA 1 |
| ATOM 836 C CA B CYS A 1 133 ? -2.381 19.079 2.483 0.50 19.36 ? 434 CYS X CA 1 |
| ATOM 837 C C . CYS A 1 133 ? -1.660 20.404 2.277 1.00 19.03 ? 434 CYS X C 1 |
| ATOM 838 O O . CYS A 1 133 ? -1.320 20.759 1.145 1.00 20.00 ? 434 CYS X O 1 |
| ATOM 839 C CB A CYS A 1 133 ? -3.626 19.002 1.692 0.50 19.11 ? 434 CYS X CB 1 |
| ATOM 840 C CB B CYS A 1 133 ? -3.724 19.133 1.750 0.50 19.75 ? 434 CYS X CB 1 |
| ATOM 841 S SG A CYS A 1 133 ? -4.564 20.500 1.907 0.50 19.17 ? 434 CYS X SG 1 |
| ATOM 842 S SG B CYS A 1 133 ? -4.656 17.604 1.815 0.50 23.48 ? 434 CYS X SG 1 |
| ATOM 843 N N . ILE A 1 134 ? -1.464 21.160 3.357 1.00 17.94 ? 435 ILE X N 1 |
| ATOM 844 C CA . ILE A 1 134 ? -0.785 22.462 3.245 1.00 17.26 ? 435 ILE X CA 1 |
| ATOM 845 C C . ILE A 1 134 ? 0.722 22.236 3.150 1.00 16.78 ? 435 ILE X C 1 |
| ATOM 846 O O . ILE A 1 134 ? 1.309 21.589 4.024 1.00 16.69 ? 435 ILE X O 1 |
| ATOM 847 C CB . ILE A 1 134 ? -1.103 23.398 4.438 1.00 17.40 ? 435 ILE X CB 1 |
| ATOM 848 C CG1 . ILE A 1 134 ? -2.616 23.665 4.544 1.00 17.99 ? 435 ILE X CG1 1 |
| ATOM 849 C CG2 . ILE A 1 134 ? -0.314 24.717 4.326 1.00 17.87 ? 435 ILE X CG2 1 |
| ATOM 850 C CD1 . ILE A 1 134 ? -3.215 24.441 3.372 1.00 20.48 ? 435 ILE X CD1 1 |
| ATOM 851 N N . HIS A 1 135 ? 1.322 22.739 2.072 1.00 15.77 ? 436 HIS X N 1 |
| ATOM 852 C CA . HIS A 1 135 ? 2.779 22.709 1.866 1.00 15.44 ? 436 HIS X CA 1 |
| ATOM 853 C C . HIS A 1 135 ? 3.328 24.089 2.191 1.00 15.52 ? 436 HIS X C 1 |
| ATOM 854 O O . HIS A 1 135 ? 2.991 25.062 1.523 1.00 15.14 ? 436 HIS X O 1 |
| ATOM 855 C CB . HIS A 1 135 ? 3.114 22.297 0.423 1.00 15.45 ? 436 HIS X CB 1 |
| ATOM 856 C CG . HIS A 1 135 ? 2.699 20.895 0.090 1.00 17.78 ? 436 HIS X CG 1 |
| ATOM 857 N ND1 . HIS A 1 135 ? 1.385 20.483 0.145 1.00 18.64 ? 436 HIS X ND1 1 |
| ATOM 858 C CD2 . HIS A 1 135 ? 3.418 19.814 -0.292 1.00 19.19 ? 436 HIS X CD2 1 |
| ATOM 859 C CE1 . HIS A 1 135 ? 1.315 19.200 -0.170 1.00 20.75 ? 436 HIS X CE1 1 |
| ATOM 860 N NE2 . HIS A 1 135 ? 2.533 18.771 -0.446 1.00 20.96 ? 436 HIS X NE2 1 |
| ATOM 861 N N . HIS A 1 136 ? 4.146 24.183 3.236 1.00 14.49 ? 437 HIS X N 1 |
| ATOM 862 C CA . HIS A 1 136 ? 4.537 25.492 3.768 1.00 14.38 ? 437 HIS X CA 1 |
| ATOM 863 C C . HIS A 1 136 ? 5.613 26.180 2.957 1.00 14.23 ? 437 HIS X C 1 |
| ATOM 864 O O . HIS A 1 136 ? 6.564 25.537 2.498 1.00 14.25 ? 437 HIS X O 1 |
| ATOM 865 C CB . HIS A 1 136 ? 5.092 25.366 5.183 1.00 14.28 ? 437 HIS X CB 1 |
| ATOM 866 C CG . HIS A 1 136 ? 4.131 24.789 6.167 1.00 15.35 ? 437 HIS X CG 1 |
| ATOM 867 N ND1 . HIS A 1 136 ? 2.852 25.269 6.331 1.00 17.64 ? 437 HIS X ND1 1 |
| ATOM 868 C CD2 . HIS A 1 136 ? 4.282 23.790 7.070 1.00 16.56 ? 437 HIS X CD2 1 |
| ATOM 869 C CE1 . HIS A 1 136 ? 2.247 24.580 7.282 1.00 18.12 ? 437 HIS X CE1 1 |
| ATOM 870 N NE2 . HIS A 1 136 ? 3.093 23.674 7.743 1.00 15.41 ? 437 HIS X NE2 1 |
| ATOM 871 N N . ASN A 1 137 ? 5.466 27.499 2.808 1.00 14.02 ? 438 ASN X N 1 |
| ATOM 872 C CA . ASN A 1 137 ? 6.599 28.334 2.440 1.00 14.75 ? 438 ASN X CA 1 |
| ATOM 873 C C . ASN A 1 137 ? 7.146 29.024 3.684 1.00 13.68 ? 438 ASN X C 1 |
| ATOM 874 O O . ASN A 1 137 ? 8.201 29.634 3.647 1.00 14.24 ? 438 ASN X O 1 |
| ATOM 875 C CB . ASN A 1 137 ? 6.231 29.365 1.348 1.00 15.41 ? 438 ASN X CB 1 |
| ATOM 876 C CG . ASN A 1 137 ? 5.129 30.338 1.786 1.00 17.65 ? 438 ASN X CG 1 |
| ATOM 877 O OD1 . ASN A 1 137 ? 4.695 30.334 2.930 1.00 20.87 ? 438 ASN X OD1 1 |
| ATOM 878 N ND2 . ASN A 1 137 ? 4.688 31.186 0.863 1.00 21.75 ? 438 ASN X ND2 1 |
| ATOM 879 N N . SER A 1 138 ? 6.420 28.939 4.793 1.00 13.61 ? 439 SER X N 1 |
| ATOM 880 C CA . SER A 1 138 ? 6.815 29.674 5.991 1.00 13.68 ? 439 SER X CA 1 |
| ATOM 881 C C . SER A 1 138 ? 8.068 29.096 6.652 1.00 13.59 ? 439 SER X C 1 |
| ATOM 882 O O . SER A 1 138 ? 8.417 27.918 6.452 1.00 13.46 ? 439 SER X O 1 |
| ATOM 883 C CB . SER A 1 138 ? 5.659 29.739 6.981 1.00 14.63 ? 439 SER X CB 1 |
| ATOM 884 O OG . SER A 1 138 ? 5.400 28.450 7.498 1.00 14.07 ? 439 SER X OG 1 |
| ATOM 885 N N . VAL A 1 139 ? 8.738 29.962 7.425 1.00 13.60 ? 440 VAL X N 1 |
| ATOM 886 C CA . VAL A 1 139 ? 9.998 29.675 8.088 1.00 13.80 ? 440 VAL X CA 1 |
| ATOM 887 C C . VAL A 1 139 ? 9.952 30.326 9.463 1.00 14.17 ? 440 VAL X C 1 |
| ATOM 888 O O . VAL A 1 139 ? 9.474 31.461 9.604 1.00 14.64 ? 440 VAL X O 1 |
| ATOM 889 C CB . VAL A 1 139 ? 11.200 30.278 7.279 1.00 14.10 ? 440 VAL X CB 1 |
| ATOM 890 C CG1 . VAL A 1 139 ? 12.546 29.976 7.960 1.00 14.53 ? 440 VAL X CG1 1 |
| ATOM 891 C CG2 . VAL A 1 139 ? 11.224 29.722 5.856 1.00 13.61 ? 440 VAL X CG2 1 |
| ATOM 892 N N . GLU A 1 140 ? 10.436 29.624 10.477 1.00 13.79 ? 441 GLU X N 1 |
| ATOM 893 C CA . GLU A 1 140 ? 10.506 30.209 11.809 1.00 14.61 ? 441 GLU X CA 1 |
| ATOM 894 C C . GLU A 1 140 ? 11.817 29.880 12.503 1.00 14.69 ? 441 GLU X C 1 |
| ATOM 895 O O . GLU A 1 140 ? 12.497 28.923 12.131 1.00 14.98 ? 441 GLU X O 1 |
| ATOM 896 C CB . GLU A 1 140 ? 9.283 29.835 12.651 1.00 14.78 ? 441 GLU X CB 1 |
| ATOM 897 C CG . GLU A 1 140 ? 8.967 28.339 12.764 1.00 15.26 ? 441 GLU X CG 1 |
| ATOM 898 C CD . GLU A 1 140 ? 7.563 28.132 13.311 1.00 16.34 ? 441 GLU X CD 1 |
| ATOM 899 O OE1 . GLU A 1 140 ? 7.310 28.535 14.478 1.00 17.80 ? 441 GLU X OE1 1 |
| ATOM 900 O OE2 . GLU A 1 140 ? 6.695 27.593 12.572 1.00 17.74 ? 441 GLU X OE2 1 |
| ATOM 901 N N . ARG A 1 141 ? 12.157 30.680 13.505 1.00 14.54 ? 442 ARG X N 1 |
| ATOM 902 C CA . ARG A 1 141 ? 13.465 30.641 14.132 1.00 16.09 ? 442 ARG X CA 1 |
| ATOM 903 C C . ARG A 1 141 ? 13.314 30.460 15.639 1.00 15.70 ? 442 ARG X C 1 |
| ATOM 904 O O . ARG A 1 141 ? 12.575 31.211 16.283 1.00 15.80 ? 442 ARG X O 1 |
| ATOM 905 C CB . ARG A 1 141 ? 14.216 31.941 13.829 1.00 15.86 ? 442 ARG X CB 1 |
| ATOM 906 C CG . ARG A 1 141 ? 15.644 31.987 14.356 1.00 17.62 ? 442 ARG X CG 1 |
| ATOM 907 C CD . ARG A 1 141 ? 16.247 33.389 14.261 1.00 19.18 ? 442 ARG X CD 1 |
| ATOM 908 N NE . ARG A 1 141 ? 15.604 34.278 15.226 1.00 25.71 ? 442 ARG X NE 1 |
| ATOM 909 C CZ . ARG A 1 141 ? 14.944 35.391 14.920 1.00 29.32 ? 442 ARG X CZ 1 |
| ATOM 910 N NH1 . ARG A 1 141 ? 14.875 35.815 13.661 1.00 31.01 ? 442 ARG X NH1 1 |
| ATOM 911 N NH2 . ARG A 1 141 ? 14.380 36.105 15.890 1.00 29.76 ? 442 ARG X NH2 1 |
| ATOM 912 N N . TYR A 1 142 ? 14.040 29.490 16.196 1.00 15.24 ? 443 TYR X N 1 |
| ATOM 913 C CA . TYR A 1 142 ? 13.990 29.187 17.633 1.00 15.76 ? 443 TYR X CA 1 |
| ATOM 914 C C . TYR A 1 142 ? 15.254 29.690 18.330 1.00 16.39 ? 443 TYR X C 1 |
| ATOM 915 O O . TYR A 1 142 ? 16.369 29.447 17.859 1.00 15.70 ? 443 TYR X O 1 |
| ATOM 916 C CB . TYR A 1 142 ? 13.856 27.678 17.842 1.00 15.63 ? 443 TYR X CB 1 |
| ATOM 917 C CG . TYR A 1 142 ? 13.821 27.219 19.292 1.00 14.99 ? 443 TYR X CG 1 |
| ATOM 918 C CD1 . TYR A 1 142 ? 12.658 27.355 20.071 1.00 15.56 ? 443 TYR X CD1 1 |
| ATOM 919 C CD2 . TYR A 1 142 ? 14.933 26.606 19.870 1.00 14.63 ? 443 TYR X CD2 1 |
| ATOM 920 C CE1 . TYR A 1 142 ? 12.624 26.918 21.411 1.00 14.48 ? 443 TYR X CE1 1 |
| ATOM 921 C CE2 . TYR A 1 142 ? 14.907 26.155 21.201 1.00 14.59 ? 443 TYR X CE2 1 |
| ATOM 922 C CZ . TYR A 1 142 ? 13.752 26.317 21.957 1.00 15.43 ? 443 TYR X CZ 1 |
| ATOM 923 O OH . TYR A 1 142 ? 13.729 25.872 23.259 1.00 16.56 ? 443 TYR X OH 1 |
| ATOM 924 N N . GLU A 1 143 ? 15.059 30.372 19.457 1.00 17.34 ? 444 GLU X N 1 |
| ATOM 925 C CA . GLU A 1 143 ? 16.148 30.853 20.303 1.00 19.37 ? 444 GLU X CA 1 |
| ATOM 926 C C . GLU A 1 143 ? 16.132 30.032 21.583 1.00 18.94 ? 444 GLU X C 1 |
| ATOM 927 O O . GLU A 1 143 ? 15.240 30.213 22.412 1.00 18.57 ? 444 GLU X O 1 |
| ATOM 928 C CB . GLU A 1 143 ? 15.962 32.346 20.618 1.00 19.26 ? 444 GLU X CB 1 |
| ATOM 929 C CG . GLU A 1 143 ? 16.111 33.230 19.381 1.00 22.71 ? 444 GLU X CG 1 |
| ATOM 930 C CD . GLU A 1 143 ? 15.752 34.685 19.629 1.00 23.64 ? 444 GLU X CD 1 |
| ATOM 931 O OE1 . GLU A 1 143 ? 16.006 35.186 20.753 1.00 29.29 ? 444 GLU X OE1 1 |
| ATOM 932 O OE2 . GLU A 1 143 ? 15.219 35.323 18.688 1.00 30.80 ? 444 GLU X OE2 1 |
| ATOM 933 N N . PRO A 1 144 ? 17.078 29.077 21.712 1.00 19.25 ? 445 PRO X N 1 |
| ATOM 934 C CA . PRO A 1 144 ? 17.162 28.207 22.884 1.00 19.50 ? 445 PRO X CA 1 |
| ATOM 935 C C . PRO A 1 144 ? 17.191 28.943 24.226 1.00 20.29 ? 445 PRO X C 1 |
| ATOM 936 O O . PRO A 1 144 ? 16.520 28.511 25.153 1.00 20.58 ? 445 PRO X O 1 |
| ATOM 937 C CB . PRO A 1 144 ? 18.442 27.396 22.635 1.00 19.22 ? 445 PRO X CB 1 |
| ATOM 938 C CG . PRO A 1 144 ? 18.539 27.343 21.110 1.00 19.36 ? 445 PRO X CG 1 |
| ATOM 939 C CD . PRO A 1 144 ? 18.087 28.722 20.690 1.00 18.98 ? 445 PRO X CD 1 |
| ATOM 940 N N . GLU A 1 145 ? 17.905 30.068 24.306 1.00 20.81 ? 446 GLU X N 1 |
| ATOM 941 C CA . GLU A 1 145 ? 18.033 30.825 25.567 1.00 21.59 ? 446 GLU X CA 1 |
| ATOM 942 C C . GLU A 1 145 ? 16.707 31.400 26.082 1.00 22.08 ? 446 GLU X C 1 |
| ATOM 943 O O . GLU A 1 145 ? 16.556 31.657 27.293 1.00 23.00 ? 446 GLU X O 1 |
| ATOM 944 C CB . GLU A 1 145 ? 19.071 31.934 25.414 1.00 21.87 ? 446 GLU X CB 1 |
| ATOM 945 N N . ARG A 1 146 ? 15.756 31.604 25.170 1.00 21.78 ? 447 ARG X N 1 |
| ATOM 946 C CA . ARG A 1 146 ? 14.445 32.164 25.508 1.00 21.20 ? 447 ARG X CA 1 |
| ATOM 947 C C . ARG A 1 146 ? 13.321 31.125 25.374 1.00 21.01 ? 447 ARG X C 1 |
| ATOM 948 O O . ARG A 1 146 ? 12.185 31.363 25.801 1.00 20.86 ? 447 ARG X O 1 |
| ATOM 949 C CB . ARG A 1 146 ? 14.156 33.376 24.625 1.00 21.45 ? 447 ARG X CB 1 |
| ATOM 950 N N . ASP A 1 147 ? 13.644 29.970 24.783 1.00 20.33 ? 448 ASP X N 1 |
| ATOM 951 C CA . ASP A 1 147 ? 12.645 28.940 24.460 1.00 20.07 ? 448 ASP X CA 1 |
| ATOM 952 C C . ASP A 1 147 ? 11.457 29.547 23.704 1.00 19.91 ? 448 ASP X C 1 |
| ATOM 953 O O . ASP A 1 147 ? 10.299 29.387 24.101 1.00 20.17 ? 448 ASP X O 1 |
| ATOM 954 C CB . ASP A 1 147 ? 12.195 28.189 25.726 1.00 19.99 ? 448 ASP X CB 1 |
| ATOM 955 C CG . ASP A 1 147 ? 11.308 26.988 25.421 1.00 20.71 ? 448 ASP X CG 1 |
| ATOM 956 O OD1 . ASP A 1 147 ? 11.534 26.296 24.406 1.00 19.28 ? 448 ASP X OD1 1 |
| ATOM 957 O OD2 . ASP A 1 147 ? 10.376 26.730 26.217 1.00 22.51 ? 448 ASP X OD2 1 |
| ATOM 958 N N . GLU A 1 148 ? 11.763 30.240 22.606 1.00 19.64 ? 449 GLU X N 1 |
| ATOM 959 C CA . GLU A 1 148 ? 10.768 30.990 21.837 1.00 20.10 ? 449 GLU X CA 1 |
| ATOM 960 C C . GLU A 1 148 ? 10.987 30.826 20.347 1.00 19.12 ? 449 GLU X C 1 |
| ATOM 961 O O . GLU A 1 148 ? 12.126 30.857 19.886 1.00 18.27 ? 449 GLU X O 1 |
| ATOM 962 C CB . GLU A 1 148 ? 10.866 32.491 22.141 1.00 20.49 ? 449 GLU X CB 1 |
| ATOM 963 C CG . GLU A 1 148 ? 10.139 32.957 23.393 1.00 23.25 ? 449 GLU X CG 1 |
| ATOM 964 C CD . GLU A 1 148 ? 10.205 34.473 23.572 1.00 23.13 ? 449 GLU X CD 1 |
| ATOM 965 O OE1 . GLU A 1 148 ? 9.737 34.968 24.623 1.00 30.35 ? 449 GLU X OE1 1 |
| ATOM 966 O OE2 . GLU A 1 148 ? 10.725 35.176 22.671 1.00 27.31 ? 449 GLU X OE2 1 |
| ATOM 967 N N . TRP A 1 149 ? 9.886 30.680 19.615 1.00 18.22 ? 450 TRP X N 1 |
| ATOM 968 C CA . TRP A 1 149 ? 9.891 30.655 18.146 1.00 18.33 ? 450 TRP X CA 1 |
| ATOM 969 C C . TRP A 1 149 ? 9.377 31.977 17.600 1.00 19.08 ? 450 TRP X C 1 |
| ATOM 970 O O . TRP A 1 149 ? 8.419 32.554 18.135 1.00 20.27 ? 450 TRP X O 1 |
| ATOM 971 C CB . TRP A 1 149 ? 8.987 29.545 17.613 1.00 17.59 ? 450 TRP X CB 1 |
| ATOM 972 C CG . TRP A 1 149 ? 9.498 28.161 17.765 1.00 16.78 ? 450 TRP X CG 1 |
| ATOM 973 C CD1 . TRP A 1 149 ? 9.212 27.289 18.778 1.00 16.28 ? 450 TRP X CD1 1 |
| ATOM 974 C CD2 . TRP A 1 149 ? 10.354 27.455 16.860 1.00 16.37 ? 450 TRP X CD2 1 |
| ATOM 975 N NE1 . TRP A 1 149 ? 9.836 26.098 18.565 1.00 15.79 ? 450 TRP X NE1 1 |
| ATOM 976 C CE2 . TRP A 1 149 ? 10.545 26.161 17.392 1.00 15.44 ? 450 TRP X CE2 1 |
| ATOM 977 C CE3 . TRP A 1 149 ? 10.981 27.794 15.653 1.00 15.27 ? 450 TRP X CE3 1 |
| ATOM 978 C CZ2 . TRP A 1 149 ? 11.339 25.194 16.756 1.00 15.53 ? 450 TRP X CZ2 1 |
| ATOM 979 C CZ3 . TRP A 1 149 ? 11.773 26.833 15.016 1.00 15.27 ? 450 TRP X CZ3 1 |
| ATOM 980 C CH2 . TRP A 1 149 ? 11.945 25.553 15.570 1.00 15.63 ? 450 TRP X CH2 1 |
| ATOM 981 N N . HIS A 1 150 ? 10.004 32.446 16.527 1.00 18.96 ? 451 HIS X N 1 |
| ATOM 982 C CA . HIS A 1 150 ? 9.566 33.652 15.839 1.00 19.90 ? 451 HIS X CA 1 |
| ATOM 983 C C . HIS A 1 150 ? 9.523 33.409 14.341 1.00 18.91 ? 451 HIS X C 1 |
| ATOM 984 O O . HIS A 1 150 ? 10.458 32.853 13.782 1.00 16.86 ? 451 HIS X O 1 |
| ATOM 985 C CB . HIS A 1 150 ? 10.494 34.820 16.172 1.00 20.99 ? 451 HIS X CB 1 |
| ATOM 986 C CG . HIS A 1 150 ? 10.495 35.178 17.628 1.00 25.09 ? 451 HIS X CG 1 |
| ATOM 987 N ND1 . HIS A 1 150 ? 9.731 36.202 18.144 1.00 30.37 ? 451 HIS X ND1 1 |
| ATOM 988 C CD2 . HIS A 1 150 ? 11.141 34.623 18.683 1.00 28.48 ? 451 HIS X CD2 1 |
| ATOM 989 C CE1 . HIS A 1 150 ? 9.912 36.269 19.453 1.00 29.63 ? 451 HIS X CE1 1 |
| ATOM 990 N NE2 . HIS A 1 150 ? 10.767 35.325 19.804 1.00 30.38 ? 451 HIS X NE2 1 |
| ATOM 991 N N . LEU A 1 151 ? 8.432 33.805 13.697 1.00 18.63 ? 452 LEU X N 1 |
| ATOM 992 C CA . LEU A 1 151 ? 8.359 33.702 12.242 1.00 18.19 ? 452 LEU X CA 1 |
| ATOM 993 C C . LEU A 1 151 ? 9.310 34.693 11.589 1.00 17.91 ? 452 LEU X C 1 |
| ATOM 994 O O . LEU A 1 151 ? 9.476 35.826 12.069 1.00 18.11 ? 452 LEU X O 1 |
| ATOM 995 C CB . LEU A 1 151 ? 6.930 33.912 11.722 1.00 19.27 ? 452 LEU X CB 1 |
| ATOM 996 C CG . LEU A 1 151 ? 5.921 32.750 11.730 1.00 20.74 ? 452 LEU X CG 1 |
| ATOM 997 C CD1 . LEU A 1 151 ? 6.350 31.615 10.795 1.00 22.27 ? 452 LEU X CD1 1 |
| ATOM 998 C CD2 . LEU A 1 151 ? 5.657 32.227 13.121 1.00 25.27 ? 452 LEU X CD2 1 |
| ATOM 999 N N . VAL A 1 152 ? 9.940 34.251 10.506 1.00 16.29 ? 453 VAL X N 1 |
| ATOM 1000 C CA . VAL A 1 152 ? 10.752 35.133 9.666 1.00 16.42 ? 453 VAL X CA 1 |
| ATOM 1001 C C . VAL A 1 152 ? 10.149 35.216 8.255 1.00 16.01 ? 453 VAL X C 1 |
| ATOM 1002 O O . VAL A 1 152 ? 9.023 34.735 8.030 1.00 15.95 ? 453 VAL X O 1 |
| ATOM 1003 C CB . VAL A 1 152 ? 12.235 34.723 9.665 1.00 16.81 ? 453 VAL X CB 1 |
| ATOM 1004 C CG1 . VAL A 1 152 ? 12.807 34.763 11.101 1.00 17.80 ? 453 VAL X CG1 1 |
| ATOM 1005 C CG2 . VAL A 1 152 ? 12.406 33.330 9.034 1.00 17.14 ? 453 VAL X CG2 1 |
| ATOM 1006 N N . ALA A 1 153 ? 10.859 35.831 7.307 1.00 15.45 ? 454 ALA X N 1 |
| ATOM 1007 C CA . ALA A 1 153 ? 10.349 35.930 5.942 1.00 15.04 ? 454 ALA X CA 1 |
| ATOM 1008 C C . ALA A 1 153 ? 10.121 34.523 5.370 1.00 14.91 ? 454 ALA X C 1 |
| ATOM 1009 O O . ALA A 1 153 ? 10.962 33.648 5.564 1.00 14.74 ? 454 ALA X O 1 |
| ATOM 1010 C CB . ALA A 1 153 ? 11.319 36.713 5.061 1.00 15.07 ? 454 ALA X CB 1 |
| ATOM 1011 N N . PRO A 1 154 ? 8.983 34.296 4.690 1.00 15.02 ? 455 PRO X N 1 |
| ATOM 1012 C CA . PRO A 1 154 ? 8.764 32.976 4.064 1.00 14.53 ? 455 PRO X CA 1 |
| ATOM 1013 C C . PRO A 1 154 ? 9.622 32.792 2.814 1.00 14.72 ? 455 PRO X C 1 |
| ATOM 1014 O O . PRO A 1 154 ? 10.028 33.771 2.174 1.00 14.55 ? 455 PRO X O 1 |
| ATOM 1015 C CB . PRO A 1 154 ? 7.294 33.025 3.642 1.00 15.56 ? 455 PRO X CB 1 |
| ATOM 1016 C CG . PRO A 1 154 ? 7.034 34.487 3.400 1.00 15.70 ? 455 PRO X CG 1 |
| ATOM 1017 C CD . PRO A 1 154 ? 7.852 35.218 4.442 1.00 15.79 ? 455 PRO X CD 1 |
| ATOM 1018 N N . MET A 1 155 ? 9.862 31.532 2.452 1.00 14.31 ? 456 MET X N 1 |
| ATOM 1019 C CA . MET A 1 155 ? 10.544 31.227 1.202 1.00 14.60 ? 456 MET X CA 1 |
| ATOM 1020 C C . MET A 1 155 ? 9.732 31.723 0.028 1.00 14.34 ? 456 MET X C 1 |
| ATOM 1021 O O . MET A 1 155 ? 8.530 31.972 0.145 1.00 15.13 ? 456 MET X O 1 |
| ATOM 1022 C CB . MET A 1 155 ? 10.738 29.718 1.040 1.00 14.50 ? 456 MET X CB 1 |
| ATOM 1023 C CG . MET A 1 155 ? 11.776 29.162 1.962 1.00 15.62 ? 456 MET X CG 1 |
| ATOM 1024 S SD . MET A 1 155 ? 11.940 27.380 1.802 1.00 15.07 ? 456 MET X SD 1 |
| ATOM 1025 C CE . MET A 1 155 ? 10.297 26.804 2.254 1.00 15.99 ? 456 MET X CE 1 |
| ATOM 1026 N N . LEU A 1 156 ? 10.398 31.839 -1.113 1.00 14.38 ? 457 LEU X N 1 |
| ATOM 1027 C CA . LEU A 1 156 ? 9.730 32.174 -2.367 1.00 14.77 ? 457 LEU X CA 1 |
| ATOM 1028 C C . LEU A 1 156 ? 8.878 31.028 -2.896 1.00 15.26 ? 457 LEU X C 1 |
| ATOM 1029 O O . LEU A 1 156 ? 7.966 31.246 -3.689 1.00 16.72 ? 457 LEU X O 1 |
| ATOM 1030 C CB . LEU A 1 156 ? 10.763 32.568 -3.422 1.00 15.09 ? 457 LEU X CB 1 |
| ATOM 1031 C CG . LEU A 1 156 ? 11.662 33.722 -2.965 1.00 16.66 ? 457 LEU X CG 1 |
| ATOM 1032 C CD1 . LEU A 1 156 ? 12.730 33.972 -4.002 1.00 16.75 ? 457 LEU X CD1 1 |
| ATOM 1033 C CD2 . LEU A 1 156 ? 10.845 34.974 -2.682 1.00 17.52 ? 457 LEU X CD2 1 |
| ATOM 1034 N N . THR A 1 157 ? 9.203 29.814 -2.461 1.00 14.94 ? 458 THR X N 1 |
| ATOM 1035 C CA . THR A 1 157 ? 8.570 28.590 -2.947 1.00 14.91 ? 458 THR X CA 1 |
| ATOM 1036 C C . THR A 1 157 ? 8.102 27.758 -1.753 1.00 14.91 ? 458 THR X C 1 |
| ATOM 1037 O O . THR A 1 157 ? 8.797 27.679 -0.736 1.00 15.21 ? 458 THR X O 1 |
| ATOM 1038 C CB . THR A 1 157 ? 9.615 27.730 -3.702 1.00 15.31 ? 458 THR X CB 1 |
| ATOM 1039 O OG1 . THR A 1 157 ? 10.424 28.579 -4.532 1.00 18.55 ? 458 THR X OG1 1 |
| ATOM 1040 C CG2 . THR A 1 157 ? 8.950 26.631 -4.534 1.00 15.33 ? 458 THR X CG2 1 |
| ATOM 1041 N N . ARG A 1 158 ? 6.942 27.118 -1.889 1.00 14.65 ? 459 ARG X N 1 |
| ATOM 1042 C CA . ARG A 1 158 ? 6.501 26.119 -0.910 1.00 14.53 ? 459 ARG X CA 1 |
| ATOM 1043 C C . ARG A 1 158 ? 7.364 24.888 -1.089 1.00 14.53 ? 459 ARG X C 1 |
| ATOM 1044 O O . ARG A 1 158 ? 7.633 24.468 -2.227 1.00 13.69 ? 459 ARG X O 1 |
| ATOM 1045 C CB . ARG A 1 158 ? 5.034 25.738 -1.121 1.00 14.65 ? 459 ARG X CB 1 |
| ATOM 1046 C CG . ARG A 1 158 ? 4.080 26.917 -0.989 1.00 15.65 ? 459 ARG X CG 1 |
| ATOM 1047 C CD . ARG A 1 158 ? 2.667 26.548 -1.353 1.00 17.23 ? 459 ARG X CD 1 |
| ATOM 1048 N NE . ARG A 1 158 ? 1.802 27.717 -1.157 1.00 19.34 ? 459 ARG X NE 1 |
| ATOM 1049 C CZ . ARG A 1 158 ? 1.217 28.037 0.000 1.00 21.58 ? 459 ARG X CZ 1 |
| ATOM 1050 N NH1 . ARG A 1 158 ? 1.376 27.277 1.085 1.00 21.31 ? 459 ARG X NH1 1 |
| ATOM 1051 N NH2 . ARG A 1 158 ? 0.452 29.123 0.079 1.00 23.16 ? 459 ARG X NH2 1 |
| ATOM 1052 N N . ARG A 1 159 ? 7.815 24.325 0.029 1.00 14.31 ? 460 ARG X N 1 |
| ATOM 1053 C CA . ARG A 1 159 ? 8.762 23.215 -0.049 1.00 15.81 ? 460 ARG X CA 1 |
| ATOM 1054 C C . ARG A 1 159 ? 8.606 22.223 1.108 1.00 15.21 ? 460 ARG X C 1 |
| ATOM 1055 O O . ARG A 1 159 ? 8.822 22.586 2.273 1.00 15.97 ? 460 ARG X O 1 |
| ATOM 1056 C CB . ARG A 1 159 ? 10.213 23.733 -0.032 1.00 14.66 ? 460 ARG X CB 1 |
| ATOM 1057 C CG . ARG A 1 159 ? 10.630 24.589 -1.209 1.00 13.84 ? 460 ARG X CG 1 |
| ATOM 1058 C CD . ARG A 1 159 ? 12.095 24.988 -1.019 1.00 14.68 ? 460 ARG X CD 1 |
| ATOM 1059 N NE . ARG A 1 159 ? 12.483 26.049 -1.938 1.00 12.59 ? 460 ARG X NE 1 |
| ATOM 1060 C CZ . ARG A 1 159 ? 13.015 25.829 -3.134 1.00 14.29 ? 460 ARG X CZ 1 |
| ATOM 1061 N NH1 . ARG A 1 159 ? 13.232 24.578 -3.548 1.00 13.74 ? 460 ARG X NH1 1 |
| ATOM 1062 N NH2 . ARG A 1 159 ? 13.321 26.861 -3.922 1.00 14.43 ? 460 ARG X NH2 1 |
| ATOM 1063 N N . ILE A 1 160 ? 8.231 20.981 0.799 1.00 15.64 ? 461 ILE X N 1 |
| ATOM 1064 C CA A ILE A 1 160 ? 8.326 19.901 1.774 0.50 15.41 ? 461 ILE X CA 1 |
| ATOM 1065 C CA B ILE A 1 160 ? 8.358 19.912 1.794 0.50 15.76 ? 461 ILE X CA 1 |
| ATOM 1066 C C . ILE A 1 160 ? 9.375 18.909 1.271 1.00 15.27 ? 461 ILE X C 1 |
| ATOM 1067 O O . ILE A 1 160 ? 9.665 18.876 0.070 1.00 14.70 ? 461 ILE X O 1 |
| ATOM 1068 C CB A ILE A 1 160 ? 6.946 19.267 2.056 0.50 15.82 ? 461 ILE X CB 1 |
| ATOM 1069 C CB B ILE A 1 160 ? 6.996 19.263 2.206 0.50 16.35 ? 461 ILE X CB 1 |
| ATOM 1070 C CG1 A ILE A 1 160 ? 6.514 18.307 0.955 0.50 16.05 ? 461 ILE X CG1 1 |
| ATOM 1071 C CG1 B ILE A 1 160 ? 6.753 17.911 1.520 0.50 17.39 ? 461 ILE X CG1 1 |
| ATOM 1072 C CG2 A ILE A 1 160 ? 5.898 20.364 2.193 0.50 15.93 ? 461 ILE X CG2 1 |
| ATOM 1073 C CG2 B ILE A 1 160 ? 5.838 20.264 2.038 0.50 16.63 ? 461 ILE X CG2 1 |
| ATOM 1074 C CD1 A ILE A 1 160 ? 5.422 17.319 1.426 0.50 15.09 ? 461 ILE X CD1 1 |
| ATOM 1075 C CD1 B ILE A 1 160 ? 6.370 18.001 0.059 0.50 18.99 ? 461 ILE X CD1 1 |
| ATOM 1076 N N . GLY A 1 161 ? 9.965 18.129 2.172 1.00 14.80 ? 462 GLY X N 1 |
| ATOM 1077 C CA . GLY A 1 161 ? 11.058 17.241 1.765 1.00 14.84 ? 462 GLY X CA 1 |
| ATOM 1078 C C . GLY A 1 161 ? 12.220 18.097 1.275 1.00 14.83 ? 462 GLY X C 1 |
| ATOM 1079 O O . GLY A 1 161 ? 12.950 17.724 0.361 1.00 15.51 ? 462 GLY X O 1 |
| ATOM 1080 N N . VAL A 1 162 ? 12.362 19.265 1.893 1.00 14.10 ? 463 VAL X N 1 |
| ATOM 1081 C CA . VAL A 1 162 ? 13.348 20.271 1.516 1.00 14.17 ? 463 VAL X CA 1 |
| ATOM 1082 C C . VAL A 1 162 ? 14.680 20.020 2.224 1.00 14.97 ? 463 VAL X C 1 |
| ATOM 1083 O O . VAL A 1 162 ? 14.716 19.724 3.418 1.00 15.44 ? 463 VAL X O 1 |
| ATOM 1084 C CB . VAL A 1 162 ? 12.789 21.672 1.886 1.00 14.17 ? 463 VAL X CB 1 |
| ATOM 1085 C CG1 . VAL A 1 162 ? 12.469 21.754 3.384 1.00 14.33 ? 463 VAL X CG1 1 |
| ATOM 1086 C CG2 . VAL A 1 162 ? 13.717 22.790 1.474 1.00 14.60 ? 463 VAL X CG2 1 |
| ATOM 1087 N N . GLY A 1 163 ? 15.778 20.151 1.482 1.00 13.77 ? 464 GLY X N 1 |
| ATOM 1088 C CA . GLY A 1 163 ? 17.102 20.025 2.079 1.00 13.62 ? 464 GLY X CA 1 |
| ATOM 1089 C C . GLY A 1 163 ? 17.551 21.389 2.546 1.00 13.30 ? 464 GLY X C 1 |
| ATOM 1090 O O . GLY A 1 163 ? 17.356 22.384 1.847 1.00 14.45 ? 464 GLY X O 1 |
| ATOM 1091 N N . VAL A 1 164 ? 18.137 21.459 3.737 1.00 12.98 ? 465 VAL X N 1 |
| ATOM 1092 C CA . VAL A 1 164 ? 18.551 22.748 4.288 1.00 13.68 ? 465 VAL X CA 1 |
| ATOM 1093 C C . VAL A 1 164 ? 19.996 22.664 4.782 1.00 13.70 ? 465 VAL X C 1 |
| ATOM 1094 O O . VAL A 1 164 ? 20.414 21.683 5.406 1.00 14.72 ? 465 VAL X O 1 |
| ATOM 1095 C CB . VAL A 1 164 ? 17.612 23.195 5.449 1.00 13.61 ? 465 VAL X CB 1 |
| ATOM 1096 C CG1 . VAL A 1 164 ? 18.120 24.480 6.116 1.00 14.29 ? 465 VAL X CG1 1 |
| ATOM 1097 C CG2 . VAL A 1 164 ? 16.205 23.399 4.915 1.00 14.20 ? 465 VAL X CG2 1 |
| ATOM 1098 N N . ALA A 1 165 ? 20.771 23.692 4.482 1.00 14.08 ? 466 ALA X N 1 |
| ATOM 1099 C CA . ALA A 1 165 ? 22.094 23.785 5.056 1.00 14.58 ? 466 ALA X CA 1 |
| ATOM 1100 C C . ALA A 1 165 ? 22.476 25.231 5.225 1.00 14.77 ? 466 ALA X C 1 |
| ATOM 1101 O O . ALA A 1 165 ? 21.842 26.129 4.651 1.00 14.43 ? 466 ALA X O 1 |
| ATOM 1102 C CB . ALA A 1 165 ? 23.095 23.070 4.178 1.00 15.61 ? 466 ALA X CB 1 |
| ATOM 1103 N N . VAL A 1 166 ? 23.522 25.439 6.018 1.00 14.55 ? 467 VAL X N 1 |
| ATOM 1104 C CA . VAL A 1 166 ? 24.020 26.773 6.335 1.00 15.46 ? 467 VAL X CA 1 |
| ATOM 1105 C C . VAL A 1 166 ? 25.447 26.909 5.823 1.00 15.99 ? 467 VAL X C 1 |
| ATOM 1106 O O . VAL A 1 166 ? 26.291 26.058 6.092 1.00 16.25 ? 467 VAL X O 1 |
| ATOM 1107 C CB . VAL A 1 166 ? 23.943 27.039 7.852 1.00 15.86 ? 467 VAL X CB 1 |
| ATOM 1108 C CG1 . VAL A 1 166 ? 24.575 28.381 8.214 1.00 16.08 ? 467 VAL X CG1 1 |
| ATOM 1109 C CG2 . VAL A 1 166 ? 22.484 27.016 8.305 1.00 16.60 ? 467 VAL X CG2 1 |
| ATOM 1110 N N . LEU A 1 167 ? 25.705 27.976 5.080 1.00 17.10 ? 468 LEU X N 1 |
| ATOM 1111 C CA . LEU A 1 167 ? 27.055 28.223 4.580 1.00 18.88 ? 468 LEU X CA 1 |
| ATOM 1112 C C . LEU A 1 167 ? 27.356 29.701 4.734 1.00 18.99 ? 468 LEU X C 1 |
| ATOM 1113 O O . LEU A 1 167 ? 26.600 30.538 4.242 1.00 18.83 ? 468 LEU X O 1 |
| ATOM 1114 C CB . LEU A 1 167 ? 27.174 27.781 3.119 1.00 19.05 ? 468 LEU X CB 1 |
| ATOM 1115 C CG . LEU A 1 167 ? 28.495 28.023 2.377 1.00 21.83 ? 468 LEU X CG 1 |
| ATOM 1116 C CD1 . LEU A 1 167 ? 29.663 27.445 3.161 1.00 22.55 ? 468 LEU X CD1 1 |
| ATOM 1117 C CD2 . LEU A 1 167 ? 28.426 27.433 0.992 1.00 21.45 ? 468 LEU X CD2 1 |
| ATOM 1118 N N . ASN A 1 168 ? 28.454 30.008 5.421 1.00 19.95 ? 469 ASN X N 1 |
| ATOM 1119 C CA . ASN A 1 168 ? 28.838 31.404 5.671 1.00 20.20 ? 469 ASN X CA 1 |
| ATOM 1120 C C . ASN A 1 168 ? 27.679 32.233 6.258 1.00 19.68 ? 469 ASN X C 1 |
| ATOM 1121 O O . ASN A 1 168 ? 27.423 33.359 5.806 1.00 20.15 ? 469 ASN X O 1 |
| ATOM 1122 C CB . ASN A 1 168 ? 29.367 32.083 4.385 1.00 21.33 ? 469 ASN X CB 1 |
| ATOM 1123 C CG . ASN A 1 168 ? 30.511 31.313 3.707 1.00 24.15 ? 469 ASN X CG 1 |
| ATOM 1124 O OD1 . ASN A 1 168 ? 31.461 30.878 4.360 1.00 28.08 ? 469 ASN X OD1 1 |
| ATOM 1125 N ND2 . ASN A 1 168 ? 30.421 31.161 2.379 1.00 27.36 ? 469 ASN X ND2 1 |
| ATOM 1126 N N . ARG A 1 169 ? 26.981 31.655 7.241 1.00 18.88 ? 470 ARG X N 1 |
| ATOM 1127 C CA A ARG A 1 169 ? 25.856 32.294 7.948 0.50 18.51 ? 470 ARG X CA 1 |
| ATOM 1128 C CA B ARG A 1 169 ? 25.882 32.348 7.943 0.50 18.82 ? 470 ARG X CA 1 |
| ATOM 1129 C C . ARG A 1 169 ? 24.688 32.711 7.035 1.00 18.15 ? 470 ARG X C 1 |
| ATOM 1130 O O . ARG A 1 169 ? 23.866 33.575 7.379 1.00 18.40 ? 470 ARG X O 1 |
| ATOM 1131 C CB A ARG A 1 169 ? 26.340 33.440 8.851 0.50 19.08 ? 470 ARG X CB 1 |
| ATOM 1132 C CB B ARG A 1 169 ? 26.405 33.585 8.699 0.50 19.62 ? 470 ARG X CB 1 |
| ATOM 1133 C CG A ARG A 1 169 ? 27.126 32.957 10.077 0.50 18.88 ? 470 ARG X CG 1 |
| ATOM 1134 C CG B ARG A 1 169 ? 27.453 33.260 9.767 0.50 21.52 ? 470 ARG X CG 1 |
| ATOM 1135 C CD A ARG A 1 169 ? 27.685 34.126 10.898 0.50 18.93 ? 470 ARG X CD 1 |
| ATOM 1136 C CD B ARG A 1 169 ? 28.447 34.412 9.979 0.50 24.31 ? 470 ARG X CD 1 |
| ATOM 1137 N NE A ARG A 1 169 ? 26.616 34.876 11.546 0.50 20.20 ? 470 ARG X NE 1 |
| ATOM 1138 N NE B ARG A 1 169 ? 29.017 34.909 8.720 0.50 26.30 ? 470 ARG X NE 1 |
| ATOM 1139 C CZ A ARG A 1 169 ? 26.140 36.047 11.129 0.50 20.97 ? 470 ARG X CZ 1 |
| ATOM 1140 C CZ B ARG A 1 169 ? 29.999 34.324 8.032 0.50 26.65 ? 470 ARG X CZ 1 |
| ATOM 1141 N NH1 A ARG A 1 169 ? 26.641 36.646 10.050 0.50 22.00 ? 470 ARG X NH1 1 |
| ATOM 1142 N NH1 B ARG A 1 169 ? 30.556 33.195 8.456 0.50 26.09 ? 470 ARG X NH1 1 |
| ATOM 1143 N NH2 A ARG A 1 169 ? 25.153 36.625 11.796 0.50 21.68 ? 470 ARG X NH2 1 |
| ATOM 1144 N NH2 B ARG A 1 169 ? 30.426 34.875 6.904 0.50 27.37 ? 470 ARG X NH2 1 |
| ATOM 1145 N N . LEU A 1 170 ? 24.603 32.061 5.873 1.00 16.96 ? 471 LEU X N 1 |
| ATOM 1146 C CA . LEU A 1 170 ? 23.404 32.149 5.036 1.00 15.96 ? 471 LEU X CA 1 |
| ATOM 1147 C C . LEU A 1 170 ? 22.696 30.788 5.054 1.00 15.69 ? 471 LEU X C 1 |
| ATOM 1148 O O . LEU A 1 170 ? 23.348 29.755 5.100 1.00 15.51 ? 471 LEU X O 1 |
| ATOM 1149 C CB . LEU A 1 170 ? 23.768 32.529 3.596 1.00 16.29 ? 471 LEU X CB 1 |
| ATOM 1150 C CG . LEU A 1 170 ? 24.471 33.878 3.393 1.00 18.61 ? 471 LEU X CG 1 |
| ATOM 1151 C CD1 . LEU A 1 170 ? 24.901 34.037 1.948 1.00 21.57 ? 471 LEU X CD1 1 |
| ATOM 1152 C CD2 . LEU A 1 170 ? 23.540 34.996 3.804 1.00 20.40 ? 471 LEU X CD2 1 |
| ATOM 1153 N N . LEU A 1 171 ? 21.368 30.813 5.000 1.00 15.09 ? 472 LEU X N 1 |
| ATOM 1154 C CA . LEU A 1 171 ? 20.548 29.605 5.039 1.00 14.78 ? 472 LEU X CA 1 |
| ATOM 1155 C C . LEU A 1 171 ? 20.131 29.234 3.616 1.00 13.88 ? 472 LEU X C 1 |
| ATOM 1156 O O . LEU A 1 171 ? 19.678 30.093 2.866 1.00 14.20 ? 472 LEU X O 1 |
| ATOM 1157 C CB . LEU A 1 171 ? 19.299 29.862 5.890 1.00 15.16 ? 472 LEU X CB 1 |
| ATOM 1158 C CG . LEU A 1 171 ? 18.346 28.705 6.174 1.00 15.16 ? 472 LEU X CG 1 |
| ATOM 1159 C CD1 . LEU A 1 171 ? 18.991 27.784 7.186 1.00 17.11 ? 472 LEU X CD1 1 |
| ATOM 1160 C CD2 . LEU A 1 171 ? 17.033 29.277 6.726 1.00 15.77 ? 472 LEU X CD2 1 |
| ATOM 1161 N N . TYR A 1 172 ? 20.263 27.960 3.254 1.00 13.76 ? 473 TYR X N 1 |
| ATOM 1162 C CA . TYR A 1 172 ? 19.929 27.492 1.911 1.00 13.76 ? 473 TYR X CA 1 |
| ATOM 1163 C C . TYR A 1 172 ? 18.819 26.467 1.998 1.00 14.00 ? 473 TYR X C 1 |
| ATOM 1164 O O . TYR A 1 172 ? 18.849 25.611 2.872 1.00 14.45 ? 473 TYR X O 1 |
| ATOM 1165 C CB . TYR A 1 172 ? 21.153 26.838 1.263 1.00 14.03 ? 473 TYR X CB 1 |
| ATOM 1166 C CG . TYR A 1 172 ? 22.200 27.857 0.874 1.00 13.86 ? 473 TYR X CG 1 |
| ATOM 1167 C CD1 . TYR A 1 172 ? 23.098 28.351 1.827 1.00 14.04 ? 473 TYR X CD1 1 |
| ATOM 1168 C CD2 . TYR A 1 172 ? 22.280 28.335 -0.438 1.00 14.77 ? 473 TYR X CD2 1 |
| ATOM 1169 C CE1 . TYR A 1 172 ? 24.054 29.305 1.489 1.00 14.03 ? 473 TYR X CE1 1 |
| ATOM 1170 C CE2 . TYR A 1 172 ? 23.243 29.275 -0.794 1.00 14.88 ? 473 TYR X CE2 1 |
| ATOM 1171 C CZ . TYR A 1 172 ? 24.116 29.752 0.175 1.00 15.84 ? 473 TYR X CZ 1 |
| ATOM 1172 O OH . TYR A 1 172 ? 25.054 30.694 -0.173 1.00 17.05 ? 473 TYR X OH 1 |
| ATOM 1173 N N . ALA A 1 173 ? 17.841 26.596 1.102 1.00 13.21 ? 474 ALA X N 1 |
| ATOM 1174 C CA . ALA A 1 173 ? 16.724 25.659 0.982 1.00 12.84 ? 474 ALA X CA 1 |
| ATOM 1175 C C . ALA A 1 173 ? 16.787 25.083 -0.424 1.00 12.65 ? 474 ALA X C 1 |
| ATOM 1176 O O . ALA A 1 173 ? 16.783 25.817 -1.410 1.00 12.71 ? 474 ALA X O 1 |
| ATOM 1177 C CB . ALA A 1 173 ? 15.380 26.364 1.242 1.00 12.82 ? 474 ALA X CB 1 |
| ATOM 1178 N N . VAL A 1 174 ? 16.851 23.755 -0.510 1.00 12.22 ? 475 VAL X N 1 |
| ATOM 1179 C CA . VAL A 1 174 ? 17.241 23.098 -1.746 1.00 12.30 ? 475 VAL X CA 1 |
| ATOM 1180 C C . VAL A 1 174 ? 16.215 22.028 -2.112 1.00 12.81 ? 475 VAL X C 1 |
| ATOM 1181 O O . VAL A 1 174 ? 15.954 21.116 -1.315 1.00 13.37 ? 475 VAL X O 1 |
| ATOM 1182 C CB . VAL A 1 174 ? 18.641 22.442 -1.592 1.00 12.81 ? 475 VAL X CB 1 |
| ATOM 1183 C CG1 . VAL A 1 174 ? 19.026 21.674 -2.849 1.00 14.21 ? 475 VAL X CG1 1 |
| ATOM 1184 C CG2 . VAL A 1 174 ? 19.683 23.499 -1.246 1.00 14.65 ? 475 VAL X CG2 1 |
| ATOM 1185 N N . GLY A 1 175 ? 15.644 22.145 -3.314 1.00 12.54 ? 476 GLY X N 1 |
| ATOM 1186 C CA . GLY A 1 175 ? 14.748 21.109 -3.840 1.00 12.71 ? 476 GLY X CA 1 |
| ATOM 1187 C C . GLY A 1 175 ? 13.464 20.981 -3.038 1.00 12.57 ? 476 GLY X C 1 |
| ATOM 1188 O O . GLY A 1 175 ? 12.994 21.952 -2.449 1.00 13.22 ? 476 GLY X O 1 |
| ATOM 1189 N N . GLY A 1 176 ? 12.893 19.782 -3.023 1.00 12.61 ? 477 GLY X N 1 |
| ATOM 1190 C CA . GLY A 1 176 ? 11.631 19.542 -2.307 1.00 13.05 ? 477 GLY X CA 1 |
| ATOM 1191 C C . GLY A 1 176 ? 10.457 19.398 -3.267 1.00 13.54 ? 477 GLY X C 1 |
| ATOM 1192 O O . GLY A 1 176 ? 10.631 19.138 -4.460 1.00 13.72 ? 477 GLY X O 1 |
| ATOM 1193 N N . PHE A 1 177 ? 9.256 19.560 -2.725 1.00 13.90 ? 478 PHE X N 1 |
| ATOM 1194 C CA . PHE A 1 177 ? 8.010 19.339 -3.459 1.00 14.99 ? 478 PHE X CA 1 |
| ATOM 1195 C C . PHE A 1 177 ? 7.088 20.479 -3.033 1.00 15.40 ? 478 PHE X C 1 |
| ATOM 1196 O O . PHE A 1 177 ? 6.926 20.737 -1.840 1.00 14.88 ? 478 PHE X O 1 |
| ATOM 1197 C CB . PHE A 1 177 ? 7.422 17.987 -3.039 1.00 15.90 ? 478 PHE X CB 1 |
| ATOM 1198 C CG . PHE A 1 177 ? 6.113 17.642 -3.700 1.00 17.54 ? 478 PHE X CG 1 |
| ATOM 1199 C CD1 . PHE A 1 177 ? 6.053 17.336 -5.064 1.00 17.47 ? 478 PHE X CD1 1 |
| ATOM 1200 C CD2 . PHE A 1 177 ? 4.941 17.586 -2.941 1.00 19.17 ? 478 PHE X CD2 1 |
| ATOM 1201 C CE1 . PHE A 1 177 ? 4.827 16.992 -5.674 1.00 18.16 ? 478 PHE X CE1 1 |
| ATOM 1202 C CE2 . PHE A 1 177 ? 3.713 17.252 -3.533 1.00 20.52 ? 478 PHE X CE2 1 |
| ATOM 1203 C CZ . PHE A 1 177 ? 3.659 16.958 -4.895 1.00 19.82 ? 478 PHE X CZ 1 |
| ATOM 1204 N N . ASP A 1 178 ? 6.492 21.154 -4.014 1.00 16.37 ? 479 ASP X N 1 |
| ATOM 1205 C CA . ASP A 1 178 ? 5.719 22.367 -3.732 1.00 17.68 ? 479 ASP X CA 1 |
| ATOM 1206 C C . ASP A 1 178 ? 4.218 22.123 -3.598 1.00 19.00 ? 479 ASP X C 1 |
| ATOM 1207 O O . ASP A 1 178 ? 3.446 23.079 -3.444 1.00 18.96 ? 479 ASP X O 1 |
| ATOM 1208 C CB . ASP A 1 178 ? 6.006 23.481 -4.759 1.00 17.39 ? 479 ASP X CB 1 |
| ATOM 1209 C CG . ASP A 1 178 ? 5.515 23.146 -6.167 1.00 18.14 ? 479 ASP X CG 1 |
| ATOM 1210 O OD1 . ASP A 1 178 ? 4.803 22.131 -6.340 1.00 19.69 ? 479 ASP X OD1 1 |
| ATOM 1211 O OD2 . ASP A 1 178 ? 5.876 23.909 -7.102 1.00 20.84 ? 479 ASP X OD2 1 |
| ATOM 1212 N N . GLY A 1 179 ? 3.814 20.854 -3.660 1.00 19.67 ? 480 GLY X N 1 |
| ATOM 1213 C CA . GLY A 1 179 ? 2.397 20.472 -3.603 1.00 21.32 ? 480 GLY X CA 1 |
| ATOM 1214 C C . GLY A 1 179 ? 1.929 19.926 -4.936 1.00 21.90 ? 480 GLY X C 1 |
| ATOM 1215 O O . GLY A 1 179 ? 0.971 19.139 -4.993 1.00 22.46 ? 480 GLY X O 1 |
| ATOM 1216 N N . THR A 1 180 ? 2.622 20.324 -6.003 1.00 22.21 ? 481 THR X N 1 |
| ATOM 1217 C CA . THR A 1 180 ? 2.317 19.872 -7.361 1.00 23.22 ? 481 THR X CA 1 |
| ATOM 1218 C C . THR A 1 180 ? 3.527 19.247 -8.053 1.00 22.77 ? 481 THR X C 1 |
| ATOM 1219 O O . THR A 1 180 ? 3.430 18.163 -8.654 1.00 23.09 ? 481 THR X O 1 |
| ATOM 1220 C CB . THR A 1 180 ? 1.774 21.042 -8.214 1.00 23.64 ? 481 THR X CB 1 |
| ATOM 1221 O OG1 . THR A 1 180 ? 0.581 21.550 -7.606 1.00 26.44 ? 481 THR X OG1 1 |
| ATOM 1222 C CG2 . THR A 1 180 ? 1.448 20.586 -9.636 1.00 25.05 ? 481 THR X CG2 1 |
| ATOM 1223 N N . ASN A 1 181 ? 4.665 19.933 -7.955 1.00 21.68 ? 482 ASN X N 1 |
| ATOM 1224 C CA . ASN A 1 181 ? 5.863 19.564 -8.692 1.00 20.72 ? 482 ASN X CA 1 |
| ATOM 1225 C C . ASN A 1 181 ? 7.029 19.311 -7.748 1.00 19.17 ? 482 ASN X C 1 |
| ATOM 1226 O O . ASN A 1 181 ? 7.158 19.988 -6.730 1.00 19.15 ? 482 ASN X O 1 |
| ATOM 1227 C CB . ASN A 1 181 ? 6.235 20.687 -9.659 1.00 21.71 ? 482 ASN X CB 1 |
| ATOM 1228 C CG . ASN A 1 181 ? 5.157 20.931 -10.709 1.00 24.40 ? 482 ASN X CG 1 |
| ATOM 1229 O OD1 . ASN A 1 181 ? 4.788 20.024 -11.451 1.00 29.70 ? 482 ASN X OD1 1 |
| ATOM 1230 N ND2 . ASN A 1 181 ? 4.646 22.152 -10.762 1.00 28.70 ? 482 ASN X ND2 1 |
| ATOM 1231 N N . ARG A 1 182 ? 7.849 18.312 -8.077 1.00 17.73 ? 483 ARG X N 1 |
| ATOM 1232 C CA . ARG A 1 182 ? 9.173 18.176 -7.461 1.00 16.82 ? 483 ARG X CA 1 |
| ATOM 1233 C C . ARG A 1 182 ? 10.114 19.229 -8.051 1.00 16.12 ? 483 ARG X C 1 |
| ATOM 1234 O O . ARG A 1 182 ? 9.959 19.632 -9.212 1.00 16.46 ? 483 ARG X O 1 |
| ATOM 1235 C CB . ARG A 1 182 ? 9.742 16.777 -7.678 1.00 17.18 ? 483 ARG X CB 1 |
| ATOM 1236 C CG . ARG A 1 182 ? 9.182 15.723 -6.745 1.00 18.46 ? 483 ARG X CG 1 |
| ATOM 1237 C CD . ARG A 1 182 ? 7.962 15.054 -7.305 1.00 20.23 ? 483 ARG X CD 1 |
| ATOM 1238 N NE . ARG A 1 182 ? 7.407 14.149 -6.310 1.00 20.62 ? 483 ARG X NE 1 |
| ATOM 1239 C CZ . ARG A 1 182 ? 6.284 13.465 -6.465 1.00 23.70 ? 483 ARG X CZ 1 |
| ATOM 1240 N NH1 . ARG A 1 182 ? 5.588 13.569 -7.595 1.00 24.30 ? 483 ARG X NH1 1 |
| ATOM 1241 N NH2 . ARG A 1 182 ? 5.853 12.684 -5.482 1.00 23.94 ? 483 ARG X NH2 1 |
| ATOM 1242 N N . LEU A 1 183 ? 11.080 19.677 -7.250 1.00 15.07 ? 484 LEU X N 1 |
| ATOM 1243 C CA . LEU A 1 183 ? 11.831 20.898 -7.574 1.00 14.90 ? 484 LEU X CA 1 |
| ATOM 1244 C C . LEU A 1 183 ? 13.315 20.657 -7.778 1.00 14.81 ? 484 LEU X C 1 |
| ATOM 1245 O O . LEU A 1 183 ? 13.914 19.871 -7.041 1.00 14.24 ? 484 LEU X O 1 |
| ATOM 1246 C CB . LEU A 1 183 ? 11.652 21.919 -6.450 1.00 15.57 ? 484 LEU X CB 1 |
| ATOM 1247 C CG . LEU A 1 183 ? 10.225 22.270 -6.030 1.00 14.87 ? 484 LEU X CG 1 |
| ATOM 1248 C CD1 . LEU A 1 183 ? 10.202 23.004 -4.684 1.00 16.87 ? 484 LEU X CD1 1 |
| ATOM 1249 C CD2 . LEU A 1 183 ? 9.533 23.084 -7.133 1.00 16.95 ? 484 LEU X CD2 1 |
| ATOM 1250 N N . ASN A 1 184 ? 13.906 21.337 -8.763 1.00 14.68 ? 485 ASN X N 1 |
| ATOM 1251 C CA . ASN A 1 184 ? 15.362 21.454 -8.828 1.00 14.19 ? 485 ASN X CA 1 |
| ATOM 1252 C C . ASN A 1 184 ? 15.839 22.825 -8.322 1.00 13.91 ? 485 ASN X C 1 |
| ATOM 1253 O O . ASN A 1 184 ? 17.043 23.071 -8.215 1.00 14.19 ? 485 ASN X O 1 |
| ATOM 1254 C CB . ASN A 1 184 ? 15.932 21.152 -10.225 1.00 14.76 ? 485 ASN X CB 1 |
| ATOM 1255 C CG . ASN A 1 184 ? 15.545 22.182 -11.273 1.00 16.48 ? 485 ASN X CG 1 |
| ATOM 1256 O OD1 . ASN A 1 184 ? 16.065 22.152 -12.389 1.00 23.85 ? 485 ASN X OD1 1 |
| ATOM 1257 N ND2 . ASN A 1 184 ? 14.649 23.084 -10.936 1.00 17.63 ? 485 ASN X ND2 1 |
| ATOM 1258 N N . SER A 1 185 ? 14.891 23.689 -7.965 1.00 13.76 ? 486 SER X N 1 |
| ATOM 1259 C CA . SER A 1 185 ? 15.252 25.035 -7.561 1.00 13.13 ? 486 SER X CA 1 |
| ATOM 1260 C C . SER A 1 185 ? 15.838 25.070 -6.154 1.00 13.50 ? 486 SER X C 1 |
| ATOM 1261 O O . SER A 1 185 ? 15.644 24.145 -5.337 1.00 13.47 ? 486 SER X O 1 |
| ATOM 1262 C CB . SER A 1 185 ? 14.053 25.970 -7.645 1.00 13.87 ? 486 SER X CB 1 |
| ATOM 1263 O OG . SER A 1 185 ? 13.088 25.640 -6.668 1.00 13.07 ? 486 SER X OG 1 |
| ATOM 1264 N N . ALA A 1 186 ? 16.564 26.150 -5.888 1.00 13.18 ? 487 ALA X N 1 |
| ATOM 1265 C CA . ALA A 1 186 ? 17.130 26.376 -4.569 1.00 12.93 ? 487 ALA X CA 1 |
| ATOM 1266 C C . ALA A 1 186 ? 17.107 27.873 -4.276 1.00 12.91 ? 487 ALA X C 1 |
| ATOM 1267 O O . ALA A 1 186 ? 17.129 28.707 -5.192 1.00 13.61 ? 487 ALA X O 1 |
| ATOM 1268 C CB . ALA A 1 186 ? 18.550 25.849 -4.506 1.00 13.99 ? 487 ALA X CB 1 |
| ATOM 1269 N N . GLU A 1 187 ? 17.034 28.208 -2.995 1.00 12.93 ? 488 GLU X N 1 |
| ATOM 1270 C CA . GLU A 1 187 ? 17.023 29.613 -2.612 1.00 12.91 ? 488 GLU X CA 1 |
| ATOM 1271 C C . GLU A 1 187 ? 17.854 29.814 -1.362 1.00 13.58 ? 488 GLU X C 1 |
| ATOM 1272 O O . GLU A 1 187 ? 18.154 28.853 -0.650 1.00 13.90 ? 488 GLU X O 1 |
| ATOM 1273 C CB . GLU A 1 187 ? 15.603 30.144 -2.435 1.00 13.29 ? 488 GLU X CB 1 |
| ATOM 1274 C CG . GLU A 1 187 ? 14.681 29.315 -1.554 1.00 14.55 ? 488 GLU X CG 1 |
| ATOM 1275 C CD . GLU A 1 187 ? 13.242 29.790 -1.703 1.00 15.64 ? 488 GLU X CD 1 |
| ATOM 1276 O OE1 . GLU A 1 187 ? 12.974 30.915 -1.221 1.00 15.69 ? 488 GLU X OE1 1 |
| ATOM 1277 O OE2 . GLU A 1 187 ? 12.403 29.066 -2.314 1.00 14.51 ? 488 GLU X OE2 1 |
| ATOM 1278 N N . CYS A 1 188 ? 18.228 31.068 -1.116 1.00 13.09 ? 489 CYS X N 1 |
| ATOM 1279 C CA A CYS A 1 188 ? 18.992 31.349 0.084 0.50 14.45 ? 489 CYS X CA 1 |
| ATOM 1280 C CA B CYS A 1 188 ? 19.132 31.459 -0.038 0.50 13.13 ? 489 CYS X CA 1 |
| ATOM 1281 C C . CYS A 1 188 ? 18.503 32.579 0.807 1.00 13.55 ? 489 CYS X C 1 |
| ATOM 1282 O O . CYS A 1 188 ? 17.940 33.517 0.227 1.00 13.76 ? 489 CYS X O 1 |
| ATOM 1283 C CB A CYS A 1 188 ? 20.479 31.430 -0.199 0.50 15.12 ? 489 CYS X CB 1 |
| ATOM 1284 C CB B CYS A 1 188 ? 20.413 31.968 -0.687 0.50 12.85 ? 489 CYS X CB 1 |
| ATOM 1285 S SG A CYS A 1 188 ? 20.925 32.838 -1.131 0.50 20.43 ? 489 CYS X SG 1 |
| ATOM 1286 S SG B CYS A 1 188 ? 21.664 32.569 0.425 0.50 12.64 ? 489 CYS X SG 1 |
| ATOM 1287 N N . TYR A 1 189 ? 18.674 32.507 2.126 1.00 13.19 ? 490 TYR X N 1 |
| ATOM 1288 C CA . TYR A 1 189 ? 18.151 33.488 3.078 1.00 13.54 ? 490 TYR X CA 1 |
| ATOM 1289 C C . TYR A 1 189 ? 19.300 34.231 3.750 1.00 14.21 ? 490 TYR X C 1 |
| ATOM 1290 O O . TYR A 1 189 ? 20.206 33.614 4.294 1.00 13.63 ? 490 TYR X O 1 |
| ATOM 1291 C CB . TYR A 1 189 ? 17.311 32.752 4.126 1.00 13.52 ? 490 TYR X CB 1 |
| ATOM 1292 C CG . TYR A 1 189 ? 16.773 33.622 5.239 1.00 12.76 ? 490 TYR X CG 1 |
| ATOM 1293 C CD1 . TYR A 1 189 ? 15.714 34.500 5.011 1.00 13.77 ? 490 TYR X CD1 1 |
| ATOM 1294 C CD2 . TYR A 1 189 ? 17.318 33.563 6.522 1.00 13.89 ? 490 TYR X CD2 1 |
| ATOM 1295 C CE1 . TYR A 1 189 ? 15.211 35.302 6.028 1.00 13.16 ? 490 TYR X CE1 1 |
| ATOM 1296 C CE2 . TYR A 1 189 ? 16.820 34.355 7.550 1.00 14.87 ? 490 TYR X CE2 1 |
| ATOM 1297 C CZ . TYR A 1 189 ? 15.766 35.221 7.300 1.00 13.75 ? 490 TYR X CZ 1 |
| ATOM 1298 O OH . TYR A 1 189 ? 15.285 35.997 8.327 1.00 14.99 ? 490 TYR X OH 1 |
| ATOM 1299 N N . TYR A 1 190 ? 19.233 35.562 3.700 1.00 14.09 ? 491 TYR X N 1 |
| ATOM 1300 C CA . TYR A 1 190 ? 20.222 36.438 4.305 1.00 14.89 ? 491 TYR X CA 1 |
| ATOM 1301 C C . TYR A 1 190 ? 19.560 37.011 5.567 1.00 15.46 ? 491 TYR X C 1 |
| ATOM 1302 O O . TYR A 1 190 ? 18.679 37.871 5.466 1.00 15.27 ? 491 TYR X O 1 |
| ATOM 1303 C CB . TYR A 1 190 ? 20.589 37.530 3.286 1.00 15.86 ? 491 TYR X CB 1 |
| ATOM 1304 C CG . TYR A 1 190 ? 21.572 38.599 3.716 1.00 17.18 ? 491 TYR X CG 1 |
| ATOM 1305 C CD1 . TYR A 1 190 ? 22.532 38.359 4.701 1.00 18.90 ? 491 TYR X CD1 1 |
| ATOM 1306 C CD2 . TYR A 1 190 ? 21.565 39.843 3.089 1.00 18.91 ? 491 TYR X CD2 1 |
| ATOM 1307 C CE1 . TYR A 1 190 ? 23.438 39.345 5.073 1.00 19.44 ? 491 TYR X CE1 1 |
| ATOM 1308 C CE2 . TYR A 1 190 ? 22.462 40.837 3.465 1.00 18.44 ? 491 TYR X CE2 1 |
| ATOM 1309 C CZ . TYR A 1 190 ? 23.392 40.578 4.454 1.00 19.43 ? 491 TYR X CZ 1 |
| ATOM 1310 O OH . TYR A 1 190 ? 24.289 41.556 4.836 1.00 21.17 ? 491 TYR X OH 1 |
| ATOM 1311 N N . PRO A 1 191 ? 19.938 36.498 6.754 1.00 15.92 ? 492 PRO X N 1 |
| ATOM 1312 C CA . PRO A 1 191 ? 19.263 36.919 7.983 1.00 16.83 ? 492 PRO X CA 1 |
| ATOM 1313 C C . PRO A 1 191 ? 19.284 38.426 8.224 1.00 17.23 ? 492 PRO X C 1 |
| ATOM 1314 O O . PRO A 1 191 ? 18.278 38.969 8.654 1.00 17.83 ? 492 PRO X O 1 |
| ATOM 1315 C CB . PRO A 1 191 ? 20.013 36.158 9.086 1.00 17.01 ? 492 PRO X CB 1 |
| ATOM 1316 C CG . PRO A 1 191 ? 20.531 34.933 8.379 1.00 17.98 ? 492 PRO X CG 1 |
| ATOM 1317 C CD . PRO A 1 191 ? 20.941 35.442 7.016 1.00 16.68 ? 492 PRO X CD 1 |
| ATOM 1318 N N . GLU A 1 192 ? 20.395 39.085 7.907 1.00 17.57 ? 493 GLU X N 1 |
| ATOM 1319 C CA . GLU A 1 192 ? 20.533 40.522 8.176 1.00 18.63 ? 493 GLU X CA 1 |
| ATOM 1320 C C . GLU A 1 192 ? 19.583 41.376 7.341 1.00 18.94 ? 493 GLU X C 1 |
| ATOM 1321 O O . GLU A 1 192 ? 19.378 42.555 7.653 1.00 20.38 ? 493 GLU X O 1 |
| ATOM 1322 C CB . GLU A 1 192 ? 21.965 40.967 7.976 1.00 18.89 ? 493 GLU X CB 1 |
| ATOM 1323 N N . ARG A 1 193 ? 19.023 40.805 6.273 1.00 18.18 ? 494 ARG X N 1 |
| ATOM 1324 C CA . ARG A 1 193 ? 18.068 41.521 5.419 1.00 17.99 ? 494 ARG X CA 1 |
| ATOM 1325 C C . ARG A 1 193 ? 16.681 40.882 5.511 1.00 17.85 ? 494 ARG X C 1 |
| ATOM 1326 O O . ARG A 1 193 ? 15.688 41.430 5.016 1.00 17.72 ? 494 ARG X O 1 |
| ATOM 1327 C CB . ARG A 1 193 ? 18.551 41.517 3.966 1.00 18.40 ? 494 ARG X CB 1 |
| ATOM 1328 C CG . ARG A 1 193 ? 17.824 42.490 3.054 1.00 19.88 ? 494 ARG X CG 1 |
| ATOM 1329 C CD . ARG A 1 193 ? 18.213 42.269 1.607 1.00 19.27 ? 494 ARG X CD 1 |
| ATOM 1330 N NE . ARG A 1 193 ? 19.471 42.920 1.251 1.00 18.94 ? 494 ARG X NE 1 |
| ATOM 1331 C CZ . ARG A 1 193 ? 19.929 43.011 0.005 1.00 19.00 ? 494 ARG X CZ 1 |
| ATOM 1332 N NH1 . ARG A 1 193 ? 19.240 42.486 -0.993 1.00 17.77 ? 494 ARG X NH1 1 |
| ATOM 1333 N NH2 . ARG A 1 193 ? 21.069 43.650 -0.249 1.00 21.47 ? 494 ARG X NH2 1 |
| ATOM 1334 N N . ASN A 1 194 ? 16.627 39.707 6.136 1.00 16.66 ? 495 ASN X N 1 |
| ATOM 1335 C CA . ASN A 1 194 ? 15.396 38.948 6.261 1.00 16.11 ? 495 ASN X CA 1 |
| ATOM 1336 C C . ASN A 1 194 ? 14.745 38.757 4.885 1.00 15.35 ? 495 ASN X C 1 |
| ATOM 1337 O O . ASN A 1 194 ? 13.568 39.052 4.691 1.00 15.56 ? 495 ASN X O 1 |
| ATOM 1338 C CB . ASN A 1 194 ? 14.446 39.630 7.252 1.00 16.53 ? 495 ASN X CB 1 |
| ATOM 1339 C CG . ASN A 1 194 ? 13.218 38.800 7.556 1.00 17.23 ? 495 ASN X CG 1 |
| ATOM 1340 O OD1 . ASN A 1 194 ? 13.278 37.569 7.631 1.00 15.33 ? 495 ASN X OD1 1 |
| ATOM 1341 N ND2 . ASN A 1 194 ? 12.082 39.474 7.707 1.00 17.95 ? 495 ASN X ND2 1 |
| ATOM 1342 N N . GLU A 1 195 ? 15.540 38.250 3.943 1.00 14.41 ? 496 GLU X N 1 |
| ATOM 1343 C CA . GLU A 1 195 ? 15.129 38.158 2.550 1.00 13.94 ? 496 GLU X CA 1 |
| ATOM 1344 C C . GLU A 1 195 ? 15.628 36.861 1.918 1.00 14.01 ? 496 GLU X C 1 |
| ATOM 1345 O O . GLU A 1 195 ? 16.786 36.473 2.118 1.00 14.30 ? 496 GLU X O 1 |
| ATOM 1346 C CB . GLU A 1 195 ? 15.718 39.344 1.792 1.00 14.74 ? 496 GLU X CB 1 |
| ATOM 1347 C CG . GLU A 1 195 ? 15.401 39.394 0.323 1.00 15.36 ? 496 GLU X CG 1 |
| ATOM 1348 C CD . GLU A 1 195 ? 15.857 40.700 -0.279 1.00 16.10 ? 496 GLU X CD 1 |
| ATOM 1349 O OE1 . GLU A 1 195 ? 15.207 41.741 -0.018 1.00 16.94 ? 496 GLU X OE1 1 |
| ATOM 1350 O OE2 . GLU A 1 195 ? 16.881 40.694 -1.000 1.00 16.42 ? 496 GLU X OE2 1 |
| ATOM 1351 N N . TRP A 1 196 ? 14.751 36.216 1.149 1.00 13.46 ? 497 TRP X N 1 |
| ATOM 1352 C CA . TRP A 1 196 ? 15.105 35.044 0.339 1.00 13.52 ? 497 TRP X CA 1 |
| ATOM 1353 C C . TRP A 1 196 ? 15.342 35.443 -1.113 1.00 12.93 ? 497 TRP X C 1 |
| ATOM 1354 O O . TRP A 1 196 ? 14.636 36.311 -1.646 1.00 13.08 ? 497 TRP X O 1 |
| ATOM 1355 C CB . TRP A 1 196 ? 13.985 34.013 0.355 1.00 13.30 ? 497 TRP X CB 1 |
| ATOM 1356 C CG . TRP A 1 196 ? 13.796 33.341 1.658 1.00 12.97 ? 497 TRP X CG 1 |
| ATOM 1357 C CD1 . TRP A 1 196 ? 12.989 33.735 2.690 1.00 14.04 ? 497 TRP X CD1 1 |
| ATOM 1358 C CD2 . TRP A 1 196 ? 14.399 32.108 2.070 1.00 12.40 ? 497 TRP X CD2 1 |
| ATOM 1359 N NE1 . TRP A 1 196 ? 13.075 32.835 3.728 1.00 14.39 ? 497 TRP X NE1 1 |
| ATOM 1360 C CE2 . TRP A 1 196 ? 13.930 31.824 3.375 1.00 13.59 ? 497 TRP X CE2 1 |
| ATOM 1361 C CE3 . TRP A 1 196 ? 15.306 31.226 1.475 1.00 13.08 ? 497 TRP X CE3 1 |
| ATOM 1362 C CZ2 . TRP A 1 196 ? 14.335 30.684 4.090 1.00 14.30 ? 497 TRP X CZ2 1 |
| ATOM 1363 C CZ3 . TRP A 1 196 ? 15.717 30.096 2.197 1.00 13.26 ? 497 TRP X CZ3 1 |
| ATOM 1364 C CH2 . TRP A 1 196 ? 15.224 29.843 3.487 1.00 13.86 ? 497 TRP X CH2 1 |
| ATOM 1365 N N . ARG A 1 197 ? 16.326 34.798 -1.751 1.00 12.67 ? 498 ARG X N 1 |
| ATOM 1366 C CA . ARG A 1 197 ? 16.582 34.941 -3.193 1.00 12.86 ? 498 ARG X CA 1 |
| ATOM 1367 C C . ARG A 1 197 ? 16.896 33.596 -3.827 1.00 13.32 ? 498 ARG X C 1 |
| ATOM 1368 O O . ARG A 1 197 ? 17.585 32.772 -3.221 1.00 12.63 ? 498 ARG X O 1 |
| ATOM 1369 C CB . ARG A 1 197 ? 17.765 35.877 -3.442 1.00 12.53 ? 498 ARG X CB 1 |
| ATOM 1370 C CG . ARG A 1 197 ? 17.396 37.333 -3.228 1.00 13.55 ? 498 ARG X CG 1 |
| ATOM 1371 C CD . ARG A 1 197 ? 18.576 38.255 -3.486 1.00 14.57 ? 498 ARG X CD 1 |
| ATOM 1372 N NE . ARG A 1 197 ? 18.118 39.616 -3.233 1.00 15.59 ? 498 ARG X NE 1 |
| ATOM 1373 C CZ . ARG A 1 197 ? 18.333 40.656 -4.031 1.00 15.36 ? 498 ARG X CZ 1 |
| ATOM 1374 N NH1 . ARG A 1 197 ? 19.095 40.537 -5.129 1.00 15.40 ? 498 ARG X NH1 1 |
| ATOM 1375 N NH2 . ARG A 1 197 ? 17.794 41.823 -3.701 1.00 15.87 ? 498 ARG X NH2 1 |
| ATOM 1376 N N . MET A 1 198 ? 16.421 33.395 -5.053 1.00 13.28 ? 499 MET X N 1 |
| ATOM 1377 C CA A MET A 1 198 ? 16.743 32.171 -5.778 0.50 14.10 ? 499 MET X CA 1 |
| ATOM 1378 C CA B MET A 1 198 ? 16.749 32.192 -5.821 0.50 13.50 ? 499 MET X CA 1 |
| ATOM 1379 C C . MET A 1 198 ? 18.232 32.147 -6.130 1.00 13.74 ? 499 MET X C 1 |
| ATOM 1380 O O . MET A 1 198 ? 18.849 33.202 -6.391 1.00 14.54 ? 499 MET X O 1 |
| ATOM 1381 C CB A MET A 1 198 ? 15.871 32.033 -7.036 0.50 14.78 ? 499 MET X CB 1 |
| ATOM 1382 C CB B MET A 1 198 ? 15.970 32.158 -7.142 0.50 13.77 ? 499 MET X CB 1 |
| ATOM 1383 C CG A MET A 1 198 ? 15.484 30.589 -7.403 0.50 17.46 ? 499 MET X CG 1 |
| ATOM 1384 C CG B MET A 1 198 ? 14.454 32.218 -6.992 0.50 13.71 ? 499 MET X CG 1 |
| ATOM 1385 S SD A MET A 1 198 ? 14.304 29.757 -6.303 0.50 22.25 ? 499 MET X SD 1 |
| ATOM 1386 S SD B MET A 1 198 ? 13.745 31.032 -5.829 0.50 14.57 ? 499 MET X SD 1 |
| ATOM 1387 C CE A MET A 1 198 ? 12.858 30.801 -6.450 0.50 21.52 ? 499 MET X CE 1 |
| ATOM 1388 C CE B MET A 1 198 ? 14.141 29.471 -6.626 0.50 16.99 ? 499 MET X CE 1 |
| ATOM 1389 N N . ILE A 1 199 ? 18.807 30.953 -6.087 1.00 13.30 ? 500 ILE X N 1 |
| ATOM 1390 C CA . ILE A 1 199 ? 20.175 30.740 -6.562 1.00 14.05 ? 500 ILE X CA 1 |
| ATOM 1391 C C . ILE A 1 199 ? 20.112 29.817 -7.779 1.00 14.25 ? 500 ILE X C 1 |
| ATOM 1392 O O . ILE A 1 199 ? 19.020 29.463 -8.256 1.00 14.29 ? 500 ILE X O 1 |
| ATOM 1393 C CB . ILE A 1 199 ? 21.122 30.162 -5.459 1.00 14.19 ? 500 ILE X CB 1 |
| ATOM 1394 C CG1 . ILE A 1 199 ? 20.642 28.783 -4.999 1.00 14.64 ? 500 ILE X CG1 1 |
| ATOM 1395 C CG2 . ILE A 1 199 ? 21.177 31.111 -4.255 1.00 15.12 ? 500 ILE X CG2 1 |
| ATOM 1396 C CD1 . ILE A 1 199 ? 21.703 27.963 -4.249 1.00 15.74 ? 500 ILE X CD1 1 |
| ATOM 1397 N N . THR A 1 200 ? 21.273 29.430 -8.290 1.00 14.45 ? 501 THR X N 1 |
| ATOM 1398 C CA . THR A 1 200 ? 21.336 28.512 -9.417 1.00 14.84 ? 501 THR X CA 1 |
| ATOM 1399 C C . THR A 1 200 ? 20.590 27.222 -9.081 1.00 14.31 ? 501 THR X C 1 |
| ATOM 1400 O O . THR A 1 200 ? 20.776 26.664 -8.001 1.00 14.83 ? 501 THR X O 1 |
| ATOM 1401 C CB . THR A 1 200 ? 22.791 28.186 -9.748 1.00 15.59 ? 501 THR X CB 1 |
| ATOM 1402 O OG1 . THR A 1 200 ? 23.474 29.414 -9.992 1.00 17.52 ? 501 THR X OG1 1 |
| ATOM 1403 C CG2 . THR A 1 200 ? 22.897 27.325 -10.981 1.00 16.69 ? 501 THR X CG2 1 |
| ATOM 1404 N N . ALA A 1 201 ? 19.745 26.766 -10.004 1.00 14.77 ? 502 ALA X N 1 |
| ATOM 1405 C CA . ALA A 1 201 ? 19.031 25.509 -9.824 1.00 14.40 ? 502 ALA X CA 1 |
| ATOM 1406 C C . ALA A 1 201 ? 19.994 24.324 -9.921 1.00 14.44 ? 502 ALA X C 1 |
| ATOM 1407 O O . ALA A 1 201 ? 21.018 24.400 -10.598 1.00 14.93 ? 502 ALA X O 1 |
| ATOM 1408 C CB . ALA A 1 201 ? 17.948 25.388 -10.873 1.00 14.81 ? 502 ALA X CB 1 |
| ATOM 1409 N N . MET A 1 202 ? 19.645 23.230 -9.245 1.00 14.55 ? 503 MET X N 1 |
| ATOM 1410 C CA . MET A 1 202 ? 20.420 21.998 -9.344 1.00 14.57 ? 503 MET X CA 1 |
| ATOM 1411 C C . MET A 1 202 ? 20.300 21.401 -10.739 1.00 14.66 ? 503 MET X C 1 |
| ATOM 1412 O O . MET A 1 202 ? 19.387 21.732 -11.505 1.00 14.99 ? 503 MET X O 1 |
| ATOM 1413 C CB . MET A 1 202 ? 19.928 20.961 -8.340 1.00 14.26 ? 503 MET X CB 1 |
| ATOM 1414 C CG . MET A 1 202 ? 20.175 21.320 -6.895 1.00 15.49 ? 503 MET X CG 1 |
| ATOM 1415 S SD . MET A 1 202 ? 19.627 19.990 -5.782 1.00 15.91 ? 503 MET X SD 1 |
| ATOM 1416 C CE . MET A 1 202 ? 17.845 20.147 -6.013 1.00 17.93 ? 503 MET X CE 1 |
| ATOM 1417 N N . ASN A 1 203 ? 21.218 20.488 -11.040 1.00 15.41 ? 504 ASN X N 1 |
| ATOM 1418 C CA . ASN A 1 203 ? 21.186 19.768 -12.303 1.00 16.70 ? 504 ASN X CA 1 |
| ATOM 1419 C C . ASN A 1 203 ? 20.000 18.809 -12.343 1.00 16.55 ? 504 ASN X C 1 |
| ATOM 1420 O O . ASN A 1 203 ? 19.473 18.502 -13.421 1.00 17.31 ? 504 ASN X O 1 |
| ATOM 1421 C CB . ASN A 1 203 ? 22.485 18.973 -12.496 1.00 17.38 ? 504 ASN X CB 1 |
| ATOM 1422 C CG . ASN A 1 203 ? 23.705 19.860 -12.669 1.00 20.15 ? 504 ASN X CG 1 |
| ATOM 1423 O OD1 . ASN A 1 203 ? 23.902 20.464 -13.729 1.00 22.39 ? 504 ASN X OD1 1 |
| ATOM 1424 N ND2 . ASN A 1 203 ? 24.537 19.938 -11.631 1.00 19.80 ? 504 ASN X ND2 1 |
| ATOM 1425 N N . THR A 1 204 ? 19.601 18.338 -11.163 1.00 15.86 ? 505 THR X N 1 |
| ATOM 1426 C CA . THR A 1 204 ? 18.592 17.302 -11.022 1.00 16.34 ? 505 THR X CA 1 |
| ATOM 1427 C C . THR A 1 204 ? 17.441 17.793 -10.130 1.00 14.92 ? 505 THR X C 1 |
| ATOM 1428 O O . THR A 1 204 ? 17.682 18.448 -9.113 1.00 15.17 ? 505 THR X O 1 |
| ATOM 1429 C CB . THR A 1 204 ? 19.197 16.034 -10.343 1.00 16.90 ? 505 THR X CB 1 |
| ATOM 1430 O OG1 . THR A 1 204 ? 20.513 15.758 -10.868 1.00 21.86 ? 505 THR X OG1 1 |
| ATOM 1431 C CG2 . THR A 1 204 ? 18.284 14.856 -10.555 1.00 19.41 ? 505 THR X CG2 1 |
| ATOM 1432 N N . ILE A 1 205 ? 16.206 17.446 -10.499 1.00 14.93 ? 506 ILE X N 1 |
| ATOM 1433 C CA . ILE A 1 205 ? 15.067 17.574 -9.596 1.00 15.06 ? 506 ILE X CA 1 |
| ATOM 1434 C C . ILE A 1 205 ? 15.302 16.624 -8.428 1.00 14.80 ? 506 ILE X C 1 |
| ATOM 1435 O O . ILE A 1 205 ? 15.591 15.436 -8.642 1.00 14.73 ? 506 ILE X O 1 |
| ATOM 1436 C CB . ILE A 1 205 ? 13.744 17.212 -10.326 1.00 14.64 ? 506 ILE X CB 1 |
| ATOM 1437 C CG1 . ILE A 1 205 ? 13.425 18.300 -11.367 1.00 16.63 ? 506 ILE X CG1 1 |
| ATOM 1438 C CG2 . ILE A 1 205 ? 12.601 17.053 -9.319 1.00 15.76 ? 506 ILE X CG2 1 |
| ATOM 1439 C CD1 . ILE A 1 205 ? 12.192 18.020 -12.209 1.00 16.75 ? 506 ILE X CD1 1 |
| ATOM 1440 N N . ARG A 1 206 ? 15.198 17.143 -7.202 1.00 14.42 ? 507 ARG X N 1 |
| ATOM 1441 C CA . ARG A 1 206 ? 15.341 16.311 -5.994 1.00 13.91 ? 507 ARG X CA 1 |
| ATOM 1442 C C . ARG A 1 206 ? 14.358 16.702 -4.921 1.00 14.61 ? 507 ARG X C 1 |
| ATOM 1443 O O . ARG A 1 206 ? 14.461 17.793 -4.362 1.00 15.18 ? 507 ARG X O 1 |
| ATOM 1444 C CB . ARG A 1 206 ? 16.745 16.426 -5.375 1.00 13.97 ? 507 ARG X CB 1 |
| ATOM 1445 C CG . ARG A 1 206 ? 17.893 16.171 -6.340 1.00 14.72 ? 507 ARG X CG 1 |
| ATOM 1446 C CD . ARG A 1 206 ? 19.219 16.335 -5.617 1.00 12.59 ? 507 ARG X CD 1 |
| ATOM 1447 N NE . ARG A 1 206 ? 20.316 16.202 -6.565 1.00 13.85 ? 507 ARG X NE 1 |
| ATOM 1448 C CZ . ARG A 1 206 ? 20.937 15.056 -6.825 1.00 13.19 ? 507 ARG X CZ 1 |
| ATOM 1449 N NH1 . ARG A 1 206 ? 20.585 13.924 -6.206 1.00 12.26 ? 507 ARG X NH1 1 |
| ATOM 1450 N NH2 . ARG A 1 206 ? 21.908 15.046 -7.731 1.00 13.93 ? 507 ARG X NH2 1 |
| ATOM 1451 N N . SER A 1 207 ? 13.445 15.796 -4.614 1.00 13.98 ? 508 SER X N 1 |
| ATOM 1452 C CA . SER A 1 207 ? 12.618 15.957 -3.440 1.00 14.57 ? 508 SER X CA 1 |
| ATOM 1453 C C . SER A 1 207 ? 13.041 14.888 -2.432 1.00 14.12 ? 508 SER X C 1 |
| ATOM 1454 O O . SER A 1 207 ? 13.287 13.737 -2.800 1.00 13.96 ? 508 SER X O 1 |
| ATOM 1455 C CB . SER A 1 207 ? 11.145 15.856 -3.799 1.00 15.38 ? 508 SER X CB 1 |
| ATOM 1456 O OG . SER A 1 207 ? 10.363 16.169 -2.669 1.00 17.26 ? 508 SER X OG 1 |
| ATOM 1457 N N . GLY A 1 208 ? 13.177 15.272 -1.164 1.00 13.01 ? 509 GLY X N 1 |
| ATOM 1458 C CA . GLY A 1 208 ? 13.608 14.302 -0.153 1.00 13.96 ? 509 GLY X CA 1 |
| ATOM 1459 C C . GLY A 1 208 ? 15.066 13.875 -0.317 1.00 13.99 ? 509 GLY X C 1 |
| ATOM 1460 O O . GLY A 1 208 ? 15.425 12.729 -0.019 1.00 14.28 ? 509 GLY X O 1 |
| ATOM 1461 N N . ALA A 1 209 ? 15.901 14.805 -0.783 1.00 13.28 ? 510 ALA X N 1 |
| ATOM 1462 C CA . ALA A 1 209 ? 17.363 14.600 -0.798 1.00 13.65 ? 510 ALA X CA 1 |
| ATOM 1463 C C . ALA A 1 209 ? 17.932 14.787 0.613 1.00 13.91 ? 510 ALA X C 1 |
| ATOM 1464 O O . ALA A 1 209 ? 17.242 15.284 1.513 1.00 15.45 ? 510 ALA X O 1 |
| ATOM 1465 C CB . ALA A 1 209 ? 18.052 15.568 -1.782 1.00 13.30 ? 510 ALA X CB 1 |
| ATOM 1466 N N . GLY A 1 210 ? 19.173 14.374 0.807 1.00 13.81 ? 511 GLY X N 1 |
| ATOM 1467 C CA . GLY A 1 210 ? 19.922 14.774 2.003 1.00 13.23 ? 511 GLY X CA 1 |
| ATOM 1468 C C . GLY A 1 210 ? 20.785 15.958 1.593 1.00 13.07 ? 511 GLY X C 1 |
| ATOM 1469 O O . GLY A 1 210 ? 21.535 15.871 0.616 1.00 13.65 ? 511 GLY X O 1 |
| ATOM 1470 N N . VAL A 1 211 ? 20.684 17.062 2.329 1.00 12.03 ? 512 VAL X N 1 |
| ATOM 1471 C CA . VAL A 1 211 ? 21.464 18.259 2.012 1.00 12.72 ? 512 VAL X CA 1 |
| ATOM 1472 C C . VAL A 1 211 ? 22.254 18.661 3.254 1.00 12.78 ? 512 VAL X C 1 |
| ATOM 1473 O O . VAL A 1 211 ? 21.693 18.717 4.352 1.00 13.96 ? 512 VAL X O 1 |
| ATOM 1474 C CB . VAL A 1 211 ? 20.542 19.412 1.556 1.00 12.44 ? 512 VAL X CB 1 |
| ATOM 1475 C CG1 . VAL A 1 211 ? 21.298 20.742 1.509 1.00 13.08 ? 512 VAL X CG1 1 |
| ATOM 1476 C CG2 . VAL A 1 211 ? 19.944 19.062 0.196 1.00 13.39 ? 512 VAL X CG2 1 |
| ATOM 1477 N N . CYS A 1 212 ? 23.547 18.919 3.073 1.00 13.03 ? 513 CYS X N 1 |
| ATOM 1478 C CA . CYS A 1 212 ? 24.403 19.339 4.179 1.00 14.85 ? 513 CYS X CA 1 |
| ATOM 1479 C C . CYS A 1 212 ? 25.577 20.143 3.645 1.00 15.07 ? 513 CYS X C 1 |
| ATOM 1480 O O . CYS A 1 212 ? 25.776 20.225 2.435 1.00 15.95 ? 513 CYS X O 1 |
| ATOM 1481 C CB . CYS A 1 212 ? 24.905 18.138 4.966 1.00 15.41 ? 513 CYS X CB 1 |
| ATOM 1482 S SG . CYS A 1 212 ? 26.116 17.160 4.057 1.00 19.53 ? 513 CYS X SG 1 |
| ATOM 1483 N N . VAL A 1 213 ? 26.319 20.775 4.553 1.00 15.15 ? 514 VAL X N 1 |
| ATOM 1484 C CA A VAL A 1 213 ? 27.521 21.506 4.175 0.50 15.63 ? 514 VAL X CA 1 |
| ATOM 1485 C CA B VAL A 1 213 ? 27.534 21.497 4.175 0.50 15.88 ? 514 VAL X CA 1 |
| ATOM 1486 C C . VAL A 1 213 ? 28.753 20.685 4.554 1.00 16.21 ? 514 VAL X C 1 |
| ATOM 1487 O O . VAL A 1 213 ? 28.793 20.084 5.631 1.00 16.66 ? 514 VAL X O 1 |
| ATOM 1488 C CB A VAL A 1 213 ? 27.541 22.925 4.811 0.50 15.63 ? 514 VAL X CB 1 |
| ATOM 1489 C CB B VAL A 1 213 ? 27.608 22.878 4.845 0.50 15.91 ? 514 VAL X CB 1 |
| ATOM 1490 C CG1 A VAL A 1 213 ? 27.730 22.861 6.331 0.50 14.52 ? 514 VAL X CG1 1 |
| ATOM 1491 C CG1 B VAL A 1 213 ? 28.978 23.526 4.638 0.50 15.69 ? 514 VAL X CG1 1 |
| ATOM 1492 C CG2 A VAL A 1 213 ? 28.603 23.812 4.156 0.50 15.14 ? 514 VAL X CG2 1 |
| ATOM 1493 C CG2 B VAL A 1 213 ? 26.551 23.763 4.282 0.50 16.09 ? 514 VAL X CG2 1 |
| ATOM 1494 N N . LEU A 1 214 ? 29.726 20.644 3.645 1.00 16.77 ? 515 LEU X N 1 |
| ATOM 1495 C CA . LEU A 1 214 ? 31.001 19.968 3.886 1.00 17.98 ? 515 LEU X CA 1 |
| ATOM 1496 C C . LEU A 1 214 ? 32.088 20.765 3.186 1.00 18.36 ? 515 LEU X C 1 |
| ATOM 1497 O O . LEU A 1 214 ? 31.984 21.050 1.990 1.00 18.31 ? 515 LEU X O 1 |
| ATOM 1498 C CB . LEU A 1 214 ? 30.965 18.529 3.363 1.00 17.88 ? 515 LEU X CB 1 |
| ATOM 1499 C CG . LEU A 1 214 ? 32.290 17.755 3.418 1.00 18.38 ? 515 LEU X CG 1 |
| ATOM 1500 C CD1 . LEU A 1 214 ? 32.654 17.402 4.866 1.00 22.68 ? 515 LEU X CD1 1 |
| ATOM 1501 C CD2 . LEU A 1 214 ? 32.212 16.504 2.562 1.00 18.87 ? 515 LEU X CD2 1 |
| ATOM 1502 N N . HIS A 1 215 ? 33.123 21.123 3.942 1.00 19.76 ? 516 HIS X N 1 |
| ATOM 1503 C CA . HIS A 1 215 ? 34.208 21.982 3.430 1.00 21.26 ? 516 HIS X CA 1 |
| ATOM 1504 C C . HIS A 1 215 ? 33.674 23.169 2.618 1.00 21.17 ? 516 HIS X C 1 |
| ATOM 1505 O O . HIS A 1 215 ? 34.108 23.402 1.493 1.00 22.15 ? 516 HIS X O 1 |
| ATOM 1506 C CB . HIS A 1 215 ? 35.203 21.177 2.574 1.00 21.97 ? 516 HIS X CB 1 |
| ATOM 1507 C CG . HIS A 1 215 ? 35.872 20.053 3.305 1.00 24.63 ? 516 HIS X CG 1 |
| ATOM 1508 N ND1 . HIS A 1 215 ? 36.511 19.020 2.651 1.00 26.09 ? 516 HIS X ND1 1 |
| ATOM 1509 C CD2 . HIS A 1 215 ? 35.995 19.795 4.629 1.00 26.53 ? 516 HIS X CD2 1 |
| ATOM 1510 C CE1 . HIS A 1 215 ? 37.005 18.178 3.541 1.00 26.72 ? 516 HIS X CE1 1 |
| ATOM 1511 N NE2 . HIS A 1 215 ? 36.700 18.620 4.748 1.00 27.51 ? 516 HIS X NE2 1 |
| ATOM 1512 N N . ASN A 1 216 ? 32.723 23.903 3.184 1.00 21.35 ? 517 ASN X N 1 |
| ATOM 1513 C CA . ASN A 1 216 ? 32.198 25.120 2.538 1.00 21.11 ? 517 ASN X CA 1 |
| ATOM 1514 C C . ASN A 1 216 ? 31.526 24.928 1.176 1.00 20.38 ? 517 ASN X C 1 |
| ATOM 1515 O O . ASN A 1 216 ? 31.420 25.870 0.386 1.00 20.25 ? 517 ASN X O 1 |
| ATOM 1516 C CB . ASN A 1 216 ? 33.288 26.191 2.434 1.00 21.26 ? 517 ASN X CB 1 |
| ATOM 1517 C CG . ASN A 1 216 ? 33.810 26.604 3.783 1.00 24.39 ? 517 ASN X CG 1 |
| ATOM 1518 O OD1 . ASN A 1 216 ? 33.037 26.870 4.712 1.00 27.02 ? 517 ASN X OD1 1 |
| ATOM 1519 N ND2 . ASN A 1 216 ? 35.125 26.630 3.914 1.00 25.18 ? 517 ASN X ND2 1 |
| ATOM 1520 N N . CYS A 1 217 ? 31.070 23.709 0.913 1.00 19.15 ? 518 CYS X N 1 |
| ATOM 1521 C CA . CYS A 1 217 ? 30.220 23.432 -0.241 1.00 18.89 ? 518 CYS X CA 1 |
| ATOM 1522 C C . CYS A 1 217 ? 28.924 22.822 0.256 1.00 17.33 ? 518 CYS X C 1 |
| ATOM 1523 O O . CYS A 1 217 ? 28.939 22.114 1.261 1.00 16.85 ? 518 CYS X O 1 |
| ATOM 1524 C CB . CYS A 1 217 ? 30.895 22.443 -1.186 1.00 19.01 ? 518 CYS X CB 1 |
| ATOM 1525 S SG . CYS A 1 217 ? 32.169 23.164 -2.205 1.00 25.79 ? 518 CYS X SG 1 |
| ATOM 1526 N N . ILE A 1 218 ? 27.826 23.088 -0.446 1.00 16.06 ? 519 ILE X N 1 |
| ATOM 1527 C CA . ILE A 1 218 ? 26.527 22.500 -0.116 1.00 15.79 ? 519 ILE X CA 1 |
| ATOM 1528 C C . ILE A 1 218 ? 26.379 21.235 -0.955 1.00 15.21 ? 519 ILE X C 1 |
| ATOM 1529 O O . ILE A 1 218 ? 26.407 21.304 -2.175 1.00 16.27 ? 519 ILE X O 1 |
| ATOM 1530 C CB . ILE A 1 218 ? 25.340 23.456 -0.497 1.00 15.73 ? 519 ILE X CB 1 |
| ATOM 1531 C CG1 . ILE A 1 218 ? 25.473 24.832 0.152 1.00 20.44 ? 519 ILE X CG1 1 |
| ATOM 1532 C CG2 . ILE A 1 218 ? 23.979 22.805 -0.201 1.00 16.80 ? 519 ILE X CG2 1 |
| ATOM 1533 C CD1 . ILE A 1 218 ? 25.194 24.865 1.619 1.00 24.02 ? 519 ILE X CD1 1 |
| ATOM 1534 N N . TYR A 1 219 ? 26.219 20.088 -0.307 1.00 13.88 ? 520 TYR X N 1 |
| ATOM 1535 C CA . TYR A 1 219 ? 25.972 18.826 -1.013 1.00 13.84 ? 520 TYR X CA 1 |
| ATOM 1536 C C . TYR A 1 219 ? 24.488 18.460 -1.005 1.00 13.63 ? 520 TYR X C 1 |
| ATOM 1537 O O . TYR A 1 219 ? 23.803 18.661 0.009 1.00 13.72 ? 520 TYR X O 1 |
| ATOM 1538 C CB . TYR A 1 219 ? 26.755 17.690 -0.345 1.00 14.14 ? 520 TYR X CB 1 |
| ATOM 1539 C CG . TYR A 1 219 ? 28.234 17.698 -0.625 1.00 14.17 ? 520 TYR X CG 1 |
| ATOM 1540 C CD1 . TYR A 1 219 ? 29.079 18.623 -0.004 1.00 13.63 ? 520 TYR X CD1 1 |
| ATOM 1541 C CD2 . TYR A 1 219 ? 28.800 16.754 -1.489 1.00 13.78 ? 520 TYR X CD2 1 |
| ATOM 1542 C CE1 . TYR A 1 219 ? 30.445 18.625 -0.260 1.00 15.77 ? 520 TYR X CE1 1 |
| ATOM 1543 C CE2 . TYR A 1 219 ? 30.161 16.748 -1.743 1.00 15.65 ? 520 TYR X CE2 1 |
| ATOM 1544 C CZ . TYR A 1 219 ? 30.977 17.684 -1.119 1.00 15.81 ? 520 TYR X CZ 1 |
| ATOM 1545 O OH . TYR A 1 219 ? 32.339 17.690 -1.354 1.00 17.70 ? 520 TYR X OH 1 |
| ATOM 1546 N N . ALA A 1 220 ? 24.009 17.914 -2.125 1.00 13.22 ? 521 ALA X N 1 |
| ATOM 1547 C CA . ALA A 1 220 ? 22.660 17.359 -2.225 1.00 12.93 ? 521 ALA X CA 1 |
| ATOM 1548 C C . ALA A 1 220 ? 22.789 15.925 -2.724 1.00 12.41 ? 521 ALA X C 1 |
| ATOM 1549 O O . ALA A 1 220 ? 23.323 15.679 -3.817 1.00 13.16 ? 521 ALA X O 1 |
| ATOM 1550 C CB . ALA A 1 220 ? 21.828 18.191 -3.168 1.00 13.23 ? 521 ALA X CB 1 |
| ATOM 1551 N N . ALA A 1 221 ? 22.385 14.978 -1.878 1.00 12.33 ? 522 ALA X N 1 |
| ATOM 1552 C CA . ALA A 1 221 ? 22.574 13.552 -2.162 1.00 11.75 ? 522 ALA X CA 1 |
| ATOM 1553 C C . ALA A 1 221 ? 21.225 12.866 -2.274 1.00 12.12 ? 522 ALA X C 1 |
| ATOM 1554 O O . ALA A 1 221 ? 20.358 13.014 -1.385 1.00 12.09 ? 522 ALA X O 1 |
| ATOM 1555 C CB . ALA A 1 221 ? 23.379 12.892 -1.053 1.00 12.17 ? 522 ALA X CB 1 |
| ATOM 1556 N N . GLY A 1 222 ? 21.056 12.092 -3.343 1.00 12.36 ? 523 GLY X N 1 |
| ATOM 1557 C CA . GLY A 1 222 ? 19.825 11.329 -3.497 1.00 12.08 ? 523 GLY X CA 1 |
| ATOM 1558 C C . GLY A 1 222 ? 18.582 12.186 -3.687 1.00 12.00 ? 523 GLY X C 1 |
| ATOM 1559 O O . GLY A 1 222 ? 18.644 13.314 -4.183 1.00 12.64 ? 523 GLY X O 1 |
| ATOM 1560 N N . GLY A 1 223 ? 17.450 11.628 -3.278 1.00 12.30 ? 524 GLY X N 1 |
| ATOM 1561 C CA . GLY A 1 223 ? 16.164 12.278 -3.493 1.00 12.03 ? 524 GLY X CA 1 |
| ATOM 1562 C C . GLY A 1 223 ? 15.364 11.549 -4.548 1.00 13.12 ? 524 GLY X C 1 |
| ATOM 1563 O O . GLY A 1 223 ? 15.787 10.508 -5.060 1.00 13.09 ? 524 GLY X O 1 |
| ATOM 1564 N N . TYR A 1 224 ? 14.221 12.137 -4.882 1.00 14.01 ? 525 TYR X N 1 |
| ATOM 1565 C CA . TYR A 1 224 ? 13.289 11.577 -5.849 1.00 14.09 ? 525 TYR X CA 1 |
| ATOM 1566 C C . TYR A 1 224 ? 13.109 12.591 -6.979 1.00 14.93 ? 525 TYR X C 1 |
| ATOM 1567 O O . TYR A 1 224 ? 12.871 13.759 -6.705 1.00 15.46 ? 525 TYR X O 1 |
| ATOM 1568 C CB . TYR A 1 224 ? 11.967 11.319 -5.134 1.00 14.63 ? 525 TYR X CB 1 |
| ATOM 1569 C CG . TYR A 1 224 ? 10.923 10.609 -5.952 1.00 14.85 ? 525 TYR X CG 1 |
| ATOM 1570 C CD1 . TYR A 1 224 ? 11.082 9.277 -6.316 1.00 16.17 ? 525 TYR X CD1 1 |
| ATOM 1571 C CD2 . TYR A 1 224 ? 9.763 11.270 -6.348 1.00 16.76 ? 525 TYR X CD2 1 |
| ATOM 1572 C CE1 . TYR A 1 224 ? 10.106 8.621 -7.068 1.00 16.73 ? 525 TYR X CE1 1 |
| ATOM 1573 C CE2 . TYR A 1 224 ? 8.783 10.622 -7.085 1.00 17.60 ? 525 TYR X CE2 1 |
| ATOM 1574 C CZ . TYR A 1 224 ? 8.961 9.299 -7.434 1.00 15.68 ? 525 TYR X CZ 1 |
| ATOM 1575 O OH . TYR A 1 224 ? 7.994 8.628 -8.188 1.00 17.05 ? 525 TYR X OH 1 |
| ATOM 1576 N N . ASP A 1 225 ? 13.234 12.156 -8.232 1.00 15.51 ? 526 ASP X N 1 |
| ATOM 1577 C CA . ASP A 1 225 ? 13.197 13.121 -9.346 1.00 16.63 ? 526 ASP X CA 1 |
| ATOM 1578 C C . ASP A 1 225 ? 11.824 13.278 -9.990 1.00 17.68 ? 526 ASP X C 1 |
| ATOM 1579 O O . ASP A 1 225 ? 11.687 13.954 -11.025 1.00 18.44 ? 526 ASP X O 1 |
| ATOM 1580 C CB . ASP A 1 225 ? 14.259 12.803 -10.404 1.00 16.71 ? 526 ASP X CB 1 |
| ATOM 1581 C CG . ASP A 1 225 ? 13.993 11.495 -11.153 1.00 17.63 ? 526 ASP X CG 1 |
| ATOM 1582 O OD1 . ASP A 1 225 ? 12.924 10.885 -10.966 1.00 17.53 ? 526 ASP X OD1 1 |
| ATOM 1583 O OD2 . ASP A 1 225 ? 14.868 11.080 -11.956 1.00 19.70 ? 526 ASP X OD2 1 |
| ATOM 1584 N N . GLY A 1 226 ? 10.822 12.657 -9.375 1.00 18.16 ? 527 GLY X N 1 |
| ATOM 1585 C CA . GLY A 1 226 ? 9.471 12.619 -9.914 1.00 18.70 ? 527 GLY X CA 1 |
| ATOM 1586 C C . GLY A 1 226 ? 9.117 11.262 -10.492 1.00 19.42 ? 527 GLY X C 1 |
| ATOM 1587 O O . GLY A 1 226 ? 7.933 10.967 -10.712 1.00 20.90 ? 527 GLY X O 1 |
| ATOM 1588 N N . GLN A 1 227 ? 10.134 10.441 -10.769 1.00 18.56 ? 528 GLN X N 1 |
| ATOM 1589 C CA . GLN A 1 227 ? 9.934 9.127 -11.383 1.00 18.55 ? 528 GLN X CA 1 |
| ATOM 1590 C C . GLN A 1 227 ? 10.670 8.021 -10.641 1.00 17.59 ? 528 GLN X C 1 |
| ATOM 1591 O O . GLN A 1 227 ? 10.167 6.901 -10.521 1.00 18.47 ? 528 GLN X O 1 |
| ATOM 1592 C CB . GLN A 1 227 ? 10.383 9.150 -12.844 1.00 19.56 ? 528 GLN X CB 1 |
| ATOM 1593 N N . ASP A 1 228 ? 11.881 8.330 -10.180 1.00 16.22 ? 529 ASP X N 1 |
| ATOM 1594 C CA A ASP A 1 228 ? 12.795 7.358 -9.576 0.50 15.71 ? 529 ASP X CA 1 |
| ATOM 1595 C CA B ASP A 1 228 ? 12.651 7.343 -9.433 0.50 15.73 ? 529 ASP X CA 1 |
| ATOM 1596 C C . ASP A 1 228 ? 13.577 8.004 -8.434 1.00 14.86 ? 529 ASP X C 1 |
| ATOM 1597 O O . ASP A 1 228 ? 13.841 9.209 -8.479 1.00 15.37 ? 529 ASP X O 1 |
| ATOM 1598 C CB A ASP A 1 228 ? 13.813 6.897 -10.632 0.50 15.80 ? 529 ASP X CB 1 |
| ATOM 1599 C CB B ASP A 1 228 ? 13.443 6.409 -10.366 0.50 16.29 ? 529 ASP X CB 1 |
| ATOM 1600 C CG A ASP A 1 228 ? 13.159 6.253 -11.847 0.50 17.38 ? 529 ASP X CG 1 |
| ATOM 1601 C CG B ASP A 1 228 ? 13.794 5.068 -9.711 0.50 17.32 ? 529 ASP X CG 1 |
| ATOM 1602 O OD1 A ASP A 1 228 ? 12.518 5.196 -11.677 0.50 19.16 ? 529 ASP X OD1 1 |
| ATOM 1603 O OD1 B ASP A 1 228 ? 13.273 4.757 -8.610 0.50 18.29 ? 529 ASP X OD1 1 |
| ATOM 1604 O OD2 A ASP A 1 228 ? 13.300 6.793 -12.974 0.50 18.24 ? 529 ASP X OD2 1 |
| ATOM 1605 O OD2 B ASP A 1 228 ? 14.590 4.314 -10.308 0.50 20.96 ? 529 ASP X OD2 1 |
| ATOM 1606 N N . GLN A 1 229 ? 13.988 7.197 -7.462 1.00 13.91 ? 530 GLN X N 1 |
| ATOM 1607 C CA . GLN A 1 229 ? 14.982 7.636 -6.502 1.00 13.51 ? 530 GLN X CA 1 |
| ATOM 1608 C C . GLN A 1 229 ? 16.341 7.741 -7.174 1.00 13.16 ? 530 GLN X C 1 |
| ATOM 1609 O O . GLN A 1 229 ? 16.627 7.065 -8.191 1.00 14.06 ? 530 GLN X O 1 |
| ATOM 1610 C CB . GLN A 1 229 ? 15.094 6.649 -5.355 1.00 13.48 ? 530 GLN X CB 1 |
| ATOM 1611 C CG . GLN A 1 229 ? 14.084 6.915 -4.258 1.00 13.78 ? 530 GLN X CG 1 |
| ATOM 1612 C CD . GLN A 1 229 ? 12.682 6.442 -4.565 1.00 16.66 ? 530 GLN X CD 1 |
| ATOM 1613 O OE1 . GLN A 1 229 ? 12.456 5.585 -5.430 1.00 15.80 ? 530 GLN X OE1 1 |
| ATOM 1614 N NE2 . GLN A 1 229 ? 11.728 6.965 -3.801 1.00 16.81 ? 530 GLN X NE2 1 |
| ATOM 1615 N N . LEU A 1 230 ? 17.182 8.582 -6.574 1.00 13.10 ? 531 LEU X N 1 |
| ATOM 1616 C CA . LEU A 1 230 ? 18.472 8.930 -7.139 1.00 12.93 ? 531 LEU X CA 1 |
| ATOM 1617 C C . LEU A 1 230 ? 19.629 8.406 -6.309 1.00 13.25 ? 531 LEU X C 1 |
| ATOM 1618 O O . LEU A 1 230 ? 19.562 8.393 -5.080 1.00 13.29 ? 531 LEU X O 1 |
| ATOM 1619 C CB . LEU A 1 230 ? 18.583 10.457 -7.202 1.00 12.61 ? 531 LEU X CB 1 |
| ATOM 1620 C CG . LEU A 1 230 ? 17.511 11.175 -8.038 1.00 12.16 ? 531 LEU X CG 1 |
| ATOM 1621 C CD1 . LEU A 1 230 ? 17.469 12.659 -7.678 1.00 13.61 ? 531 LEU X CD1 1 |
| ATOM 1622 C CD2 . LEU A 1 230 ? 17.726 10.968 -9.551 1.00 17.58 ? 531 LEU X CD2 1 |
| ATOM 1623 N N . ASN A 1 231 ? 20.715 8.003 -6.973 1.00 13.40 ? 532 ASN X N 1 |
| ATOM 1624 C CA . ASN A 1 231 ? 21.965 7.851 -6.227 1.00 14.21 ? 532 ASN X CA 1 |
| ATOM 1625 C C . ASN A 1 231 ? 22.978 8.949 -6.499 1.00 13.38 ? 532 ASN X C 1 |
| ATOM 1626 O O . ASN A 1 231 ? 24.026 8.991 -5.860 1.00 14.15 ? 532 ASN X O 1 |
| ATOM 1627 C CB . ASN A 1 231 ? 22.601 6.475 -6.381 1.00 15.51 ? 532 ASN X CB 1 |
| ATOM 1628 C CG . ASN A 1 231 ? 22.775 6.066 -7.805 1.00 18.02 ? 532 ASN X CG 1 |
| ATOM 1629 O OD1 . ASN A 1 231 ? 22.785 4.869 -8.096 1.00 25.61 ? 532 ASN X OD1 1 |
| ATOM 1630 N ND2 . ASN A 1 231 ? 22.921 7.025 -8.707 1.00 19.21 ? 532 ASN X ND2 1 |
| ATOM 1631 N N . SER A 1 232 ? 22.649 9.864 -7.408 1.00 12.96 ? 533 SER X N 1 |
| ATOM 1632 C CA . SER A 1 232 ? 23.595 10.911 -7.741 1.00 12.62 ? 533 SER X CA 1 |
| ATOM 1633 C C . SER A 1 232 ? 23.720 11.912 -6.592 1.00 12.70 ? 533 SER X C 1 |
| ATOM 1634 O O . SER A 1 232 ? 22.824 12.033 -5.719 1.00 13.76 ? 533 SER X O 1 |
| ATOM 1635 C CB . SER A 1 232 ? 23.187 11.628 -9.029 1.00 12.62 ? 533 SER X CB 1 |
| ATOM 1636 O OG . SER A 1 232 ? 22.001 12.363 -8.841 1.00 13.31 ? 533 SER X OG 1 |
| ATOM 1637 N N . VAL A 1 233 ? 24.836 12.629 -6.606 1.00 12.08 ? 534 VAL X N 1 |
| ATOM 1638 C CA . VAL A 1 233 ? 25.180 13.582 -5.555 1.00 12.41 ? 534 VAL X CA 1 |
| ATOM 1639 C C . VAL A 1 233 ? 25.794 14.791 -6.265 1.00 12.82 ? 534 VAL X C 1 |
| ATOM 1640 O O . VAL A 1 233 ? 26.661 14.631 -7.126 1.00 13.15 ? 534 VAL X O 1 |
| ATOM 1641 C CB . VAL A 1 233 ? 26.216 12.990 -4.575 1.00 12.98 ? 534 VAL X CB 1 |
| ATOM 1642 C CG1 . VAL A 1 233 ? 26.548 13.996 -3.481 1.00 14.02 ? 534 VAL X CG1 1 |
| ATOM 1643 C CG2 . VAL A 1 233 ? 25.697 11.678 -3.950 1.00 13.13 ? 534 VAL X CG2 1 |
| ATOM 1644 N N . GLU A 1 234 ? 25.321 15.986 -5.936 1.00 12.37 ? 535 GLU X N 1 |
| ATOM 1645 C CA . GLU A 1 234 ? 25.935 17.178 -6.512 1.00 13.06 ? 535 GLU X CA 1 |
| ATOM 1646 C C . GLU A 1 234 ? 26.258 18.192 -5.423 1.00 13.64 ? 535 GLU X C 1 |
| ATOM 1647 O O . GLU A 1 234 ? 25.674 18.164 -4.349 1.00 13.91 ? 535 GLU X O 1 |
| ATOM 1648 C CB . GLU A 1 234 ? 25.072 17.773 -7.617 1.00 13.83 ? 535 GLU X CB 1 |
| ATOM 1649 C CG . GLU A 1 234 ? 23.655 18.129 -7.228 1.00 14.59 ? 535 GLU X CG 1 |
| ATOM 1650 C CD . GLU A 1 234 ? 22.814 18.435 -8.474 1.00 16.13 ? 535 GLU X CD 1 |
| ATOM 1651 O OE1 . GLU A 1 234 ? 23.178 19.387 -9.217 1.00 17.38 ? 535 GLU X OE1 1 |
| ATOM 1652 O OE2 . GLU A 1 234 ? 21.816 17.722 -8.716 1.00 17.25 ? 535 GLU X OE2 1 |
| ATOM 1653 N N . ARG A 1 235 ? 27.242 19.044 -5.685 1.00 13.54 ? 536 ARG X N 1 |
| ATOM 1654 C CA . ARG A 1 235 ? 27.613 20.036 -4.686 1.00 14.12 ? 536 ARG X CA 1 |
| ATOM 1655 C C . ARG A 1 235 ? 27.632 21.427 -5.282 1.00 13.77 ? 536 ARG X C 1 |
| ATOM 1656 O O . ARG A 1 235 ? 27.990 21.597 -6.440 1.00 13.75 ? 536 ARG X O 1 |
| ATOM 1657 C CB . ARG A 1 235 ? 28.944 19.710 -4.018 1.00 15.51 ? 536 ARG X CB 1 |
| ATOM 1658 C CG . ARG A 1 235 ? 30.143 19.850 -4.909 1.00 15.91 ? 536 ARG X CG 1 |
| ATOM 1659 C CD . ARG A 1 235 ? 31.403 19.467 -4.156 1.00 17.94 ? 536 ARG X CD 1 |
| ATOM 1660 N NE . ARG A 1 235 ? 32.560 19.525 -5.038 1.00 18.45 ? 536 ARG X NE 1 |
| ATOM 1661 C CZ . ARG A 1 235 ? 33.647 18.768 -4.895 1.00 18.43 ? 536 ARG X CZ 1 |
| ATOM 1662 N NH1 . ARG A 1 235 ? 33.746 17.902 -3.891 1.00 19.32 ? 536 ARG X NH1 1 |
| ATOM 1663 N NH2 . ARG A 1 235 ? 34.643 18.891 -5.756 1.00 20.53 ? 536 ARG X NH2 1 |
| ATOM 1664 N N . TYR A 1 236 ? 27.228 22.403 -4.475 1.00 13.29 ? 537 TYR X N 1 |
| ATOM 1665 C CA . TYR A 1 236 ? 27.164 23.789 -4.900 1.00 13.83 ? 537 TYR X CA 1 |
| ATOM 1666 C C . TYR A 1 236 ? 28.326 24.581 -4.314 1.00 14.27 ? 537 TYR X C 1 |
| ATOM 1667 O O . TYR A 1 236 ? 28.619 24.484 -3.120 1.00 14.23 ? 537 TYR X O 1 |
| ATOM 1668 C CB . TYR A 1 236 ? 25.851 24.411 -4.457 1.00 13.90 ? 537 TYR X CB 1 |
| ATOM 1669 C CG . TYR A 1 236 ? 25.663 25.850 -4.910 1.00 14.00 ? 537 TYR X CG 1 |
| ATOM 1670 C CD1 . TYR A 1 236 ? 25.425 26.155 -6.248 1.00 16.24 ? 537 TYR X CD1 1 |
| ATOM 1671 C CD2 . TYR A 1 236 ? 25.704 26.891 -3.986 1.00 15.28 ? 537 TYR X CD2 1 |
| ATOM 1672 C CE1 . TYR A 1 236 ? 25.232 27.488 -6.661 1.00 16.24 ? 537 TYR X CE1 1 |
| ATOM 1673 C CE2 . TYR A 1 236 ? 25.521 28.221 -4.388 1.00 15.70 ? 537 TYR X CE2 1 |
| ATOM 1674 C CZ . TYR A 1 236 ? 25.300 28.503 -5.725 1.00 15.80 ? 537 TYR X CZ 1 |
| ATOM 1675 O OH . TYR A 1 236 ? 25.136 29.830 -6.104 1.00 18.52 ? 537 TYR X OH 1 |
| ATOM 1676 N N . ASP A 1 237 ? 28.988 25.352 -5.169 1.00 15.44 ? 538 ASP X N 1 |
| ATOM 1677 C CA . ASP A 1 237 ? 30.029 26.267 -4.734 1.00 16.67 ? 538 ASP X CA 1 |
| ATOM 1678 C C . ASP A 1 237 ? 29.525 27.695 -4.931 1.00 16.87 ? 538 ASP X C 1 |
| ATOM 1679 O O . ASP A 1 237 ? 29.232 28.095 -6.068 1.00 16.81 ? 538 ASP X O 1 |
| ATOM 1680 C CB . ASP A 1 237 ? 31.296 26.044 -5.562 1.00 17.31 ? 538 ASP X CB 1 |
| ATOM 1681 C CG . ASP A 1 237 ? 32.497 26.777 -4.992 1.00 19.94 ? 538 ASP X CG 1 |
| ATOM 1682 O OD1 . ASP A 1 237 ? 33.628 26.426 -5.383 1.00 20.87 ? 538 ASP X OD1 1 |
| ATOM 1683 O OD2 . ASP A 1 237 ? 32.304 27.684 -4.142 1.00 22.51 ? 538 ASP X OD2 1 |
| ATOM 1684 N N . VAL A 1 238 ? 29.442 28.461 -3.841 1.00 17.31 ? 539 VAL X N 1 |
| ATOM 1685 C CA A VAL A 1 238 ? 28.897 29.822 -3.908 0.50 18.02 ? 539 VAL X CA 1 |
| ATOM 1686 C CA B VAL A 1 238 ? 28.900 29.827 -3.891 0.50 18.17 ? 539 VAL X CA 1 |
| ATOM 1687 C C . VAL A 1 238 ? 29.812 30.757 -4.692 1.00 18.52 ? 539 VAL X C 1 |
| ATOM 1688 O O . VAL A 1 238 ? 29.356 31.762 -5.255 1.00 19.52 ? 539 VAL X O 1 |
| ATOM 1689 C CB A VAL A 1 238 ? 28.591 30.426 -2.504 0.50 18.27 ? 539 VAL X CB 1 |
| ATOM 1690 C CB B VAL A 1 238 ? 28.678 30.410 -2.469 0.50 18.45 ? 539 VAL X CB 1 |
| ATOM 1691 C CG1 A VAL A 1 238 ? 27.473 29.669 -1.827 0.50 19.01 ? 539 VAL X CG1 1 |
| ATOM 1692 C CG1 B VAL A 1 238 ? 27.823 31.686 -2.517 0.50 18.47 ? 539 VAL X CG1 1 |
| ATOM 1693 C CG2 A VAL A 1 238 ? 29.836 30.467 -1.623 0.50 17.67 ? 539 VAL X CG2 1 |
| ATOM 1694 C CG2 B VAL A 1 238 ? 28.021 29.385 -1.585 0.50 19.38 ? 539 VAL X CG2 1 |
| ATOM 1695 N N . GLU A 1 239 ? 31.100 30.416 -4.741 1.00 18.43 ? 540 GLU X N 1 |
| ATOM 1696 C CA . GLU A 1 239 ? 32.077 31.234 -5.455 1.00 19.60 ? 540 GLU X CA 1 |
| ATOM 1697 C C . GLU A 1 239 ? 31.935 31.156 -6.967 1.00 19.44 ? 540 GLU X C 1 |
| ATOM 1698 O O . GLU A 1 239 ? 32.102 32.167 -7.660 1.00 21.15 ? 540 GLU X O 1 |
| ATOM 1699 C CB . GLU A 1 239 ? 33.502 30.882 -5.028 1.00 20.02 ? 540 GLU X CB 1 |
| ATOM 1700 C CG . GLU A 1 239 ? 33.816 31.294 -3.593 1.00 23.86 ? 540 GLU X CG 1 |
| ATOM 1701 C CD . GLU A 1 239 ? 35.300 31.221 -3.263 1.00 29.06 ? 540 GLU X CD 1 |
| ATOM 1702 O OE1 . GLU A 1 239 ? 36.132 31.491 -4.157 1.00 32.26 ? 540 GLU X OE1 1 |
| ATOM 1703 O OE2 . GLU A 1 239 ? 35.632 30.895 -2.101 1.00 32.47 ? 540 GLU X OE2 1 |
| ATOM 1704 N N . THR A 1 240 ? 31.608 29.966 -7.470 1.00 18.27 ? 541 THR X N 1 |
| ATOM 1705 C CA . THR A 1 240 ? 31.452 29.747 -8.904 1.00 17.81 ? 541 THR X CA 1 |
| ATOM 1706 C C . THR A 1 240 ? 29.975 29.717 -9.308 1.00 17.77 ? 541 THR X C 1 |
| ATOM 1707 O O . THR A 1 240 ? 29.663 29.700 -10.502 1.00 17.64 ? 541 THR X O 1 |
| ATOM 1708 C CB . THR A 1 240 ? 32.077 28.418 -9.352 1.00 18.06 ? 541 THR X CB 1 |
| ATOM 1709 O OG1 . THR A 1 240 ? 31.318 27.342 -8.783 1.00 17.05 ? 541 THR X OG1 1 |
| ATOM 1710 C CG2 . THR A 1 240 ? 33.550 28.315 -8.924 1.00 18.86 ? 541 THR X CG2 1 |
| ATOM 1711 N N . GLU A 1 241 ? 29.086 29.687 -8.310 1.00 17.59 ? 542 GLU X N 1 |
| ATOM 1712 C CA . GLU A 1 241 ? 27.632 29.596 -8.541 1.00 18.51 ? 542 GLU X CA 1 |
| ATOM 1713 C C . GLU A 1 241 ? 27.252 28.401 -9.418 1.00 17.92 ? 542 GLU X C 1 |
| ATOM 1714 O O . GLU A 1 241 ? 26.332 28.477 -10.234 1.00 18.54 ? 542 GLU X O 1 |
| ATOM 1715 C CB . GLU A 1 241 ? 27.091 30.924 -9.116 1.00 18.41 ? 542 GLU X CB 1 |
| ATOM 1716 C CG . GLU A 1 241 ? 27.405 32.133 -8.231 1.00 20.85 ? 542 GLU X CG 1 |
| ATOM 1717 C CD . GLU A 1 241 ? 26.847 33.437 -8.769 1.00 22.54 ? 542 GLU X CD 1 |
| ATOM 1718 O OE1 . GLU A 1 241 ? 26.508 33.495 -9.970 1.00 27.40 ? 542 GLU X OE1 1 |
| ATOM 1719 O OE2 . GLU A 1 241 ? 26.738 34.405 -7.980 1.00 28.34 ? 542 GLU X OE2 1 |
| ATOM 1720 N N . THR A 1 242 ? 27.964 27.291 -9.230 1.00 16.25 ? 543 THR X N 1 |
| ATOM 1721 C CA . THR A 1 242 ? 27.798 26.104 -10.049 1.00 15.89 ? 543 THR X CA 1 |
| ATOM 1722 C C . THR A 1 242 ? 27.566 24.877 -9.180 1.00 14.64 ? 543 THR X C 1 |
| ATOM 1723 O O . THR A 1 242 ? 28.186 24.735 -8.127 1.00 14.33 ? 543 THR X O 1 |
| ATOM 1724 C CB . THR A 1 242 ? 29.068 25.892 -10.913 1.00 16.22 ? 543 THR X CB 1 |
| ATOM 1725 O OG1 . THR A 1 242 ? 29.276 27.074 -11.705 1.00 17.50 ? 543 THR X OG1 1 |
| ATOM 1726 C CG2 . THR A 1 242 ? 28.950 24.663 -11.822 1.00 18.56 ? 543 THR X CG2 1 |
| ATOM 1727 N N . TRP A 1 243 ? 26.642 24.024 -9.622 1.00 13.49 ? 544 TRP X N 1 |
| ATOM 1728 C CA . TRP A 1 243 ? 26.450 22.690 -9.067 1.00 13.56 ? 544 TRP X CA 1 |
| ATOM 1729 C C . TRP A 1 243 ? 27.243 21.692 -9.900 1.00 14.44 ? 544 TRP X C 1 |
| ATOM 1730 O O . TRP A 1 243 ? 27.111 21.666 -11.124 1.00 15.72 ? 544 TRP X O 1 |
| ATOM 1731 C CB . TRP A 1 243 ? 24.980 22.292 -9.154 1.00 13.82 ? 544 TRP X CB 1 |
| ATOM 1732 C CG . TRP A 1 243 ? 24.067 23.036 -8.228 1.00 12.41 ? 544 TRP X CG 1 |
| ATOM 1733 C CD1 . TRP A 1 243 ? 23.365 24.190 -8.502 1.00 13.04 ? 544 TRP X CD1 1 |
| ATOM 1734 C CD2 . TRP A 1 243 ? 23.720 22.665 -6.890 1.00 11.91 ? 544 TRP X CD2 1 |
| ATOM 1735 N NE1 . TRP A 1 243 ? 22.605 24.551 -7.413 1.00 12.81 ? 544 TRP X NE1 1 |
| ATOM 1736 C CE2 . TRP A 1 243 ? 22.817 23.644 -6.402 1.00 12.93 ? 544 TRP X CE2 1 |
| ATOM 1737 C CE3 . TRP A 1 243 ? 24.103 21.613 -6.046 1.00 13.32 ? 544 TRP X CE3 1 |
| ATOM 1738 C CZ2 . TRP A 1 243 ? 22.274 23.594 -5.112 1.00 13.05 ? 544 TRP X CZ2 1 |
| ATOM 1739 C CZ3 . TRP A 1 243 ? 23.561 21.563 -4.753 1.00 12.76 ? 544 TRP X CZ3 1 |
| ATOM 1740 C CH2 . TRP A 1 243 ? 22.649 22.549 -4.305 1.00 12.99 ? 544 TRP X CH2 1 |
| ATOM 1741 N N . THR A 1 244 ? 28.039 20.861 -9.242 1.00 13.78 ? 545 THR X N 1 |
| ATOM 1742 C CA . THR A 1 244 ? 28.854 19.868 -9.923 1.00 14.97 ? 545 THR X CA 1 |
| ATOM 1743 C C . THR A 1 244 ? 28.569 18.483 -9.338 1.00 14.64 ? 545 THR X C 1 |
| ATOM 1744 O O . THR A 1 244 ? 28.460 18.339 -8.126 1.00 15.12 ? 545 THR X O 1 |
| ATOM 1745 C CB . THR A 1 244 ? 30.348 20.209 -9.761 1.00 15.35 ? 545 THR X CB 1 |
| ATOM 1746 O OG1 . THR A 1 244 ? 30.588 21.531 -10.281 1.00 17.96 ? 545 THR X OG1 1 |
| ATOM 1747 C CG2 . THR A 1 244 ? 31.232 19.192 -10.488 1.00 17.37 ? 545 THR X CG2 1 |
| ATOM 1748 N N . PHE A 1 245 ? 28.466 17.469 -10.196 1.00 14.33 ? 546 PHE X N 1 |
| ATOM 1749 C CA . PHE A 1 245 ? 28.358 16.095 -9.703 1.00 14.54 ? 546 PHE X CA 1 |
| ATOM 1750 C C . PHE A 1 245 ? 29.648 15.596 -9.070 1.00 14.35 ? 546 PHE X C 1 |
| ATOM 1751 O O . PHE A 1 245 ? 30.761 15.875 -9.566 1.00 14.82 ? 546 PHE X O 1 |
| ATOM 1752 C CB . PHE A 1 245 ? 27.931 15.153 -10.826 1.00 14.68 ? 546 PHE X CB 1 |
| ATOM 1753 C CG . PHE A 1 245 ? 26.498 15.324 -11.207 1.00 15.39 ? 546 PHE X CG 1 |
| ATOM 1754 C CD1 . PHE A 1 245 ? 25.491 14.832 -10.378 1.00 15.55 ? 546 PHE X CD1 1 |
| ATOM 1755 C CD2 . PHE A 1 245 ? 26.142 16.025 -12.354 1.00 16.21 ? 546 PHE X CD2 1 |
| ATOM 1756 C CE1 . PHE A 1 245 ? 24.160 14.992 -10.711 1.00 16.67 ? 546 PHE X CE1 1 |
| ATOM 1757 C CE2 . PHE A 1 245 ? 24.787 16.204 -12.681 1.00 16.75 ? 546 PHE X CE2 1 |
| ATOM 1758 C CZ . PHE A 1 245 ? 23.804 15.684 -11.852 1.00 15.96 ? 546 PHE X CZ 1 |
| ATOM 1759 N N . VAL A 1 246 ? 29.489 14.867 -7.971 1.00 14.06 ? 547 VAL X N 1 |
| ATOM 1760 C CA . VAL A 1 246 ? 30.587 14.082 -7.405 1.00 14.09 ? 547 VAL X CA 1 |
| ATOM 1761 C C . VAL A 1 246 ? 30.251 12.590 -7.528 1.00 13.57 ? 547 VAL X C 1 |
| ATOM 1762 O O . VAL A 1 246 ? 29.336 12.230 -8.251 1.00 13.85 ? 547 VAL X O 1 |
| ATOM 1763 C CB . VAL A 1 246 ? 30.947 14.509 -5.956 1.00 14.45 ? 547 VAL X CB 1 |
| ATOM 1764 C CG1 . VAL A 1 246 ? 31.361 15.986 -5.934 1.00 16.12 ? 547 VAL X CG1 1 |
| ATOM 1765 C CG2 . VAL A 1 246 ? 29.801 14.239 -4.967 1.00 15.38 ? 547 VAL X CG2 1 |
| ATOM 1766 N N . ALA A 1 247 ? 31.014 11.723 -6.872 1.00 13.65 ? 548 ALA X N 1 |
| ATOM 1767 C CA . ALA A 1 247 ? 30.761 10.283 -6.975 1.00 14.00 ? 548 ALA X CA 1 |
| ATOM 1768 C C . ALA A 1 247 ? 29.357 9.964 -6.458 1.00 14.20 ? 548 ALA X C 1 |
| ATOM 1769 O O . ALA A 1 247 ? 28.934 10.550 -5.472 1.00 14.01 ? 548 ALA X O 1 |
| ATOM 1770 C CB . ALA A 1 247 ? 31.807 9.526 -6.193 1.00 14.46 ? 548 ALA X CB 1 |
| ATOM 1771 N N . PRO A 1 248 ? 28.618 9.093 -7.169 1.00 14.71 ? 549 PRO X N 1 |
| ATOM 1772 C CA . PRO A 1 248 ? 27.290 8.708 -6.703 1.00 14.01 ? 549 PRO X CA 1 |
| ATOM 1773 C C . PRO A 1 248 ? 27.346 7.714 -5.548 1.00 14.39 ? 549 PRO X C 1 |
| ATOM 1774 O O . PRO A 1 248 ? 28.318 6.950 -5.405 1.00 14.24 ? 549 PRO X O 1 |
| ATOM 1775 C CB . PRO A 1 248 ? 26.653 8.054 -7.935 1.00 14.88 ? 549 PRO X CB 1 |
| ATOM 1776 C CG . PRO A 1 248 ? 27.818 7.470 -8.670 1.00 14.56 ? 549 PRO X CG 1 |
| ATOM 1777 C CD . PRO A 1 248 ? 28.939 8.470 -8.470 1.00 14.68 ? 549 PRO X CD 1 |
| ATOM 1778 N N . MET A 1 249 ? 26.291 7.722 -4.739 1.00 14.09 ? 550 MET X N 1 |
| ATOM 1779 C CA . MET A 1 249 ? 26.125 6.715 -3.715 1.00 13.79 ? 550 MET X CA 1 |
| ATOM 1780 C C . MET A 1 249 ? 25.920 5.359 -4.369 1.00 13.73 ? 550 MET X C 1 |
| ATOM 1781 O O . MET A 1 249 ? 25.494 5.274 -5.529 1.00 13.04 ? 550 MET X O 1 |
| ATOM 1782 C CB . MET A 1 249 ? 24.907 7.028 -2.853 1.00 13.99 ? 550 MET X CB 1 |
| ATOM 1783 C CG . MET A 1 249 ? 24.980 8.355 -2.146 1.00 13.79 ? 550 MET X CG 1 |
| ATOM 1784 S SD . MET A 1 249 ? 23.467 8.695 -1.218 1.00 15.18 ? 550 MET X SD 1 |
| ATOM 1785 C CE . MET A 1 249 ? 22.259 8.853 -2.549 1.00 15.85 ? 550 MET X CE 1 |
| ATOM 1786 N N . LYS A 1 250 ? 26.212 4.304 -3.619 1.00 13.92 ? 551 LYS X N 1 |
| ATOM 1787 C CA . LYS A 1 250 ? 25.973 2.943 -4.098 1.00 14.68 ? 551 LYS X CA 1 |
| ATOM 1788 C C . LYS A 1 250 ? 24.468 2.667 -4.209 1.00 14.82 ? 551 LYS X C 1 |
| ATOM 1789 O O . LYS A 1 250 ? 24.001 2.074 -5.182 1.00 16.31 ? 551 LYS X O 1 |
| ATOM 1790 C CB . LYS A 1 250 ? 26.641 1.947 -3.170 1.00 14.96 ? 551 LYS X CB 1 |
| ATOM 1791 N N . HIS A 1 251 ? 23.712 3.138 -3.212 1.00 13.69 ? 552 HIS X N 1 |
| ATOM 1792 C CA . HIS A 1 251 ? 22.279 2.840 -3.123 1.00 13.63 ? 552 HIS X CA 1 |
| ATOM 1793 C C . HIS A 1 251 ? 21.414 4.090 -3.281 1.00 13.23 ? 552 HIS X C 1 |
| ATOM 1794 O O . HIS A 1 251 ? 21.517 5.022 -2.472 1.00 14.23 ? 552 HIS X O 1 |
| ATOM 1795 C CB . HIS A 1 251 ? 21.973 2.169 -1.776 1.00 14.47 ? 552 HIS X CB 1 |
| ATOM 1796 C CG . HIS A 1 251 ? 22.770 0.923 -1.537 1.00 16.08 ? 552 HIS X CG 1 |
| ATOM 1797 N ND1 . HIS A 1 251 ? 22.571 -0.231 -2.267 1.00 18.48 ? 552 HIS X ND1 1 |
| ATOM 1798 C CD2 . HIS A 1 251 ? 23.798 0.664 -0.690 1.00 18.07 ? 552 HIS X CD2 1 |
| ATOM 1799 C CE1 . HIS A 1 251 ? 23.434 -1.153 -1.870 1.00 17.95 ? 552 HIS X CE1 1 |
| ATOM 1800 N NE2 . HIS A 1 251 ? 24.184 -0.639 -0.910 1.00 18.90 ? 552 HIS X NE2 1 |
| ATOM 1801 N N . ARG A 1 252 ? 20.555 4.091 -4.304 1.00 13.16 ? 553 ARG X N 1 |
| ATOM 1802 C CA A ARG A 1 252 ? 19.621 5.196 -4.519 0.50 12.67 ? 553 ARG X CA 1 |
| ATOM 1803 C CA B ARG A 1 252 ? 19.612 5.189 -4.519 0.50 13.16 ? 553 ARG X CA 1 |
| ATOM 1804 C C . ARG A 1 252 ? 18.664 5.283 -3.341 1.00 12.99 ? 553 ARG X C 1 |
| ATOM 1805 O O . ARG A 1 252 ? 18.295 4.259 -2.761 1.00 12.96 ? 553 ARG X O 1 |
| ATOM 1806 C CB A ARG A 1 252 ? 18.850 4.988 -5.817 0.50 13.18 ? 553 ARG X CB 1 |
| ATOM 1807 C CB B ARG A 1 252 ? 18.835 4.988 -5.819 0.50 13.42 ? 553 ARG X CB 1 |
| ATOM 1808 C CG A ARG A 1 252 ? 17.779 3.937 -5.719 0.50 13.98 ? 553 ARG X CG 1 |
| ATOM 1809 C CG B ARG A 1 252 ? 18.003 3.712 -5.904 0.50 14.67 ? 553 ARG X CG 1 |
| ATOM 1810 C CD A ARG A 1 252 ? 17.112 3.697 -7.048 0.50 15.74 ? 553 ARG X CD 1 |
| ATOM 1811 C CD B ARG A 1 252 ? 17.413 3.545 -7.303 0.50 15.04 ? 553 ARG X CD 1 |
| ATOM 1812 N NE A ARG A 1 252 ? 16.009 2.762 -6.869 0.50 16.41 ? 553 ARG X NE 1 |
| ATOM 1813 N NE B ARG A 1 252 ? 18.438 3.267 -8.312 0.50 18.70 ? 553 ARG X NE 1 |
| ATOM 1814 C CZ A ARG A 1 252 ? 16.154 1.450 -6.723 0.50 17.36 ? 553 ARG X CZ 1 |
| ATOM 1815 C CZ B ARG A 1 252 ? 18.947 4.166 -9.157 0.50 20.28 ? 553 ARG X CZ 1 |
| ATOM 1816 N NH1 A ARG A 1 252 ? 17.367 0.898 -6.761 0.50 16.49 ? 553 ARG X NH1 1 |
| ATOM 1817 N NH1 B ARG A 1 252 ? 18.523 5.422 -9.154 0.50 21.82 ? 553 ARG X NH1 1 |
| ATOM 1818 N NH2 A ARG A 1 252 ? 15.082 0.688 -6.544 0.50 17.32 ? 553 ARG X NH2 1 |
| ATOM 1819 N NH2 B ARG A 1 252 ? 19.882 3.803 -10.024 0.50 22.12 ? 553 ARG X NH2 1 |
| ATOM 1820 N N . ARG A 1 253 ? 18.281 6.505 -2.981 1.00 11.83 ? 554 ARG X N 1 |
| ATOM 1821 C CA . ARG A 1 253 ? 17.456 6.669 -1.780 1.00 11.92 ? 554 ARG X CA 1 |
| ATOM 1822 C C . ARG A 1 253 ? 16.865 8.066 -1.739 1.00 12.00 ? 554 ARG X C 1 |
| ATOM 1823 O O . ARG A 1 253 ? 17.508 9.038 -2.158 1.00 12.09 ? 554 ARG X O 1 |
| ATOM 1824 C CB . ARG A 1 253 ? 18.312 6.453 -0.524 1.00 11.65 ? 554 ARG X CB 1 |
| ATOM 1825 C CG . ARG A 1 253 ? 19.592 7.293 -0.466 1.00 13.13 ? 554 ARG X CG 1 |
| ATOM 1826 C CD . ARG A 1 253 ? 20.405 6.942 0.781 1.00 12.67 ? 554 ARG X CD 1 |
| ATOM 1827 N NE . ARG A 1 253 ? 21.342 5.829 0.580 1.00 13.21 ? 554 ARG X NE 1 |
| ATOM 1828 C CZ . ARG A 1 253 ? 21.722 4.999 1.552 1.00 13.48 ? 554 ARG X CZ 1 |
| ATOM 1829 N NH1 . ARG A 1 253 ? 21.171 5.070 2.774 1.00 13.31 ? 554 ARG X NH1 1 |
| ATOM 1830 N NH2 . ARG A 1 253 ? 22.633 4.079 1.292 1.00 14.83 ? 554 ARG X NH2 1 |
| ATOM 1831 N N . SER A 1 254 ? 15.644 8.144 -1.215 1.00 11.90 ? 555 SER X N 1 |
| ATOM 1832 C CA . SER A 1 254 ? 15.048 9.429 -0.827 1.00 12.62 ? 555 SER X CA 1 |
| ATOM 1833 C C . SER A 1 254 ? 14.571 9.322 0.627 1.00 12.61 ? 555 SER X C 1 |
| ATOM 1834 O O . SER A 1 254 ? 14.524 8.224 1.184 1.00 12.08 ? 555 SER X O 1 |
| ATOM 1835 C CB . SER A 1 254 ? 13.898 9.795 -1.775 1.00 13.28 ? 555 SER X CB 1 |
| ATOM 1836 O OG . SER A 1 254 ? 12.864 8.818 -1.786 1.00 12.69 ? 555 SER X OG 1 |
| ATOM 1837 N N . ALA A 1 255 ? 14.257 10.459 1.252 1.00 12.28 ? 556 ALA X N 1 |
| ATOM 1838 C CA . ALA A 1 255 ? 13.864 10.492 2.666 1.00 13.29 ? 556 ALA X CA 1 |
| ATOM 1839 C C . ALA A 1 255 ? 14.972 9.843 3.514 1.00 13.20 ? 556 ALA X C 1 |
| ATOM 1840 O O . ALA A 1 255 ? 14.731 9.066 4.432 1.00 13.28 ? 556 ALA X O 1 |
| ATOM 1841 C CB . ALA A 1 255 ? 12.481 9.808 2.877 1.00 13.43 ? 556 ALA X CB 1 |
| ATOM 1842 N N . LEU A 1 256 ? 16.210 10.154 3.137 1.00 13.64 ? 557 LEU X N 1 |
| ATOM 1843 C CA . LEU A 1 256 ? 17.398 9.772 3.911 1.00 14.24 ? 557 LEU X CA 1 |
| ATOM 1844 C C . LEU A 1 256 ? 17.719 10.825 4.977 1.00 14.79 ? 557 LEU X C 1 |
| ATOM 1845 O O . LEU A 1 256 ? 17.224 11.956 4.920 1.00 16.14 ? 557 LEU X O 1 |
| ATOM 1846 C CB . LEU A 1 256 ? 18.603 9.591 2.966 1.00 14.79 ? 557 LEU X CB 1 |
| ATOM 1847 C CG . LEU A 1 256 ? 18.993 10.834 2.152 1.00 15.34 ? 557 LEU X CG 1 |
| ATOM 1848 C CD1 . LEU A 1 256 ? 20.496 10.933 1.911 1.00 18.44 ? 557 LEU X CD1 1 |
| ATOM 1849 C CD2 . LEU A 1 256 ? 18.239 10.937 0.833 1.00 14.59 ? 557 LEU X CD2 1 |
| ATOM 1850 N N . GLY A 1 257 ? 18.525 10.434 5.960 1.00 14.06 ? 558 GLY X N 1 |
| ATOM 1851 C CA . GLY A 1 257 ? 19.125 11.391 6.885 1.00 15.07 ? 558 GLY X CA 1 |
| ATOM 1852 C C . GLY A 1 257 ? 20.567 11.604 6.465 1.00 15.26 ? 558 GLY X C 1 |
| ATOM 1853 O O . GLY A 1 257 ? 21.230 10.674 6.030 1.00 16.63 ? 558 GLY X O 1 |
| ATOM 1854 N N . ILE A 1 258 ? 21.041 12.836 6.563 1.00 15.18 ? 559 ILE X N 1 |
| ATOM 1855 C CA . ILE A 1 258 ? 22.427 13.130 6.223 1.00 15.13 ? 559 ILE X CA 1 |
| ATOM 1856 C C . ILE A 1 258 ? 23.098 13.930 7.338 1.00 15.01 ? 559 ILE X C 1 |
| ATOM 1857 O O . ILE A 1 258 ? 22.471 14.778 7.985 1.00 15.13 ? 559 ILE X O 1 |
| ATOM 1858 C CB . ILE A 1 258 ? 22.473 13.903 4.884 1.00 15.32 ? 559 ILE X CB 1 |
| ATOM 1859 C CG1 . ILE A 1 258 ? 23.888 13.913 4.310 1.00 15.39 ? 559 ILE X CG1 1 |
| ATOM 1860 C CG2 . ILE A 1 258 ? 21.891 15.330 5.046 1.00 15.82 ? 559 ILE X CG2 1 |
| ATOM 1861 C CD1 . ILE A 1 258 ? 23.970 14.363 2.852 1.00 16.18 ? 559 ILE X CD1 1 |
| ATOM 1862 N N . THR A 1 259 ? 24.375 13.654 7.566 1.00 14.18 ? 560 THR X N 1 |
| ATOM 1863 C CA . THR A 1 259 ? 25.144 14.454 8.517 1.00 15.35 ? 560 THR X CA 1 |
| ATOM 1864 C C . THR A 1 259 ? 26.630 14.399 8.204 1.00 15.51 ? 560 THR X C 1 |
| ATOM 1865 O O . THR A 1 259 ? 27.058 13.641 7.336 1.00 15.51 ? 560 THR X O 1 |
| ATOM 1866 C CB . THR A 1 259 ? 24.857 14.029 9.977 1.00 16.33 ? 560 THR X CB 1 |
| ATOM 1867 O OG1 . THR A 1 259 ? 25.304 15.049 10.871 1.00 18.95 ? 560 THR X OG1 1 |
| ATOM 1868 C CG2 . THR A 1 259 ? 25.536 12.698 10.322 1.00 16.32 ? 560 THR X CG2 1 |
| ATOM 1869 N N . VAL A 1 260 ? 27.408 15.223 8.898 1.00 14.75 ? 561 VAL X N 1 |
| ATOM 1870 C CA . VAL A 1 260 ? 28.849 15.263 8.708 1.00 14.80 ? 561 VAL X CA 1 |
| ATOM 1871 C C . VAL A 1 260 ? 29.511 14.912 10.033 1.00 14.69 ? 561 VAL X C 1 |
| ATOM 1872 O O . VAL A 1 260 ? 29.126 15.422 11.086 1.00 15.19 ? 561 VAL X O 1 |
| ATOM 1873 C CB . VAL A 1 260 ? 29.312 16.653 8.272 1.00 14.79 ? 561 VAL X CB 1 |
| ATOM 1874 C CG1 . VAL A 1 260 ? 30.837 16.760 8.309 1.00 16.43 ? 561 VAL X CG1 1 |
| ATOM 1875 C CG2 . VAL A 1 260 ? 28.770 16.976 6.891 1.00 15.81 ? 561 VAL X CG2 1 |
| ATOM 1876 N N . HIS A 1 261 ? 30.476 14.006 9.962 1.00 14.41 ? 562 HIS X N 1 |
| ATOM 1877 C CA . HIS A 1 261 ? 31.247 13.603 11.141 1.00 15.69 ? 562 HIS X CA 1 |
| ATOM 1878 C C . HIS A 1 261 ? 32.700 13.567 10.709 1.00 16.83 ? 562 HIS X C 1 |
| ATOM 1879 O O . HIS A 1 261 ? 33.046 12.856 9.759 1.00 17.21 ? 562 HIS X O 1 |
| ATOM 1880 C CB . HIS A 1 261 ? 30.782 12.234 11.614 1.00 15.67 ? 562 HIS X CB 1 |
| ATOM 1881 C CG . HIS A 1 261 ? 31.520 11.715 12.809 1.00 16.44 ? 562 HIS X CG 1 |
| ATOM 1882 N ND1 . HIS A 1 261 ? 32.760 11.125 12.717 1.00 18.19 ? 562 HIS X ND1 1 |
| ATOM 1883 C CD2 . HIS A 1 261 ? 31.172 11.665 14.118 1.00 18.34 ? 562 HIS X CD2 1 |
| ATOM 1884 C CE1 . HIS A 1 261 ? 33.161 10.761 13.924 1.00 17.85 ? 562 HIS X CE1 1 |
| ATOM 1885 N NE2 . HIS A 1 261 ? 32.215 11.073 14.789 1.00 18.50 ? 562 HIS X NE2 1 |
| ATOM 1886 N N . GLN A 1 262 ? 33.534 14.353 11.403 1.00 17.87 ? 563 GLN X N 1 |
| ATOM 1887 C CA A GLN A 1 262 ? 34.980 14.405 11.139 0.50 18.43 ? 563 GLN X CA 1 |
| ATOM 1888 C CA B GLN A 1 262 ? 34.977 14.407 11.140 0.50 18.15 ? 563 GLN X CA 1 |
| ATOM 1889 C C . GLN A 1 262 ? 35.297 14.508 9.644 1.00 17.77 ? 563 GLN X C 1 |
| ATOM 1890 O O . GLN A 1 262 ? 36.069 13.716 9.099 1.00 17.99 ? 563 GLN X O 1 |
| ATOM 1891 C CB A GLN A 1 262 ? 35.707 13.213 11.783 0.50 18.54 ? 563 GLN X CB 1 |
| ATOM 1892 C CB B GLN A 1 262 ? 35.698 13.218 11.796 0.50 18.58 ? 563 GLN X CB 1 |
| ATOM 1893 C CG A GLN A 1 262 ? 35.982 13.384 13.271 0.50 20.34 ? 563 GLN X CG 1 |
| ATOM 1894 C CG B GLN A 1 262 ? 35.633 13.220 13.319 0.50 20.89 ? 563 GLN X CG 1 |
| ATOM 1895 C CD A GLN A 1 262 ? 36.518 12.126 13.934 0.50 20.26 ? 563 GLN X CD 1 |
| ATOM 1896 C CD B GLN A 1 262 ? 36.400 14.379 13.933 0.50 22.46 ? 563 GLN X CD 1 |
| ATOM 1897 O OE1 A GLN A 1 262 ? 37.286 11.366 13.339 0.50 22.36 ? 563 GLN X OE1 1 |
| ATOM 1898 O OE1 B GLN A 1 262 ? 37.630 14.405 13.911 0.50 24.52 ? 563 GLN X OE1 1 |
| ATOM 1899 N NE2 A GLN A 1 262 ? 36.128 11.910 15.186 0.50 22.55 ? 563 GLN X NE2 1 |
| ATOM 1900 N NE2 B GLN A 1 262 ? 35.673 15.345 14.484 0.50 23.43 ? 563 GLN X NE2 1 |
| ATOM 1901 N N . GLY A 1 263 ? 34.667 15.482 8.980 1.00 17.29 ? 564 GLY X N 1 |
| ATOM 1902 C CA . GLY A 1 263 ? 34.984 15.787 7.583 1.00 16.75 ? 564 GLY X CA 1 |
| ATOM 1903 C C . GLY A 1 263 ? 34.518 14.789 6.528 1.00 16.55 ? 564 GLY X C 1 |
| ATOM 1904 O O . GLY A 1 263 ? 35.002 14.809 5.397 1.00 16.82 ? 564 GLY X O 1 |
| ATOM 1905 N N . ARG A 1 264 ? 33.603 13.902 6.909 1.00 16.05 ? 565 ARG X N 1 |
| ATOM 1906 C CA . ARG A 1 264 ? 32.992 12.959 5.981 1.00 16.46 ? 565 ARG X CA 1 |
| ATOM 1907 C C . ARG A 1 264 ? 31.474 13.035 6.097 1.00 15.60 ? 565 ARG X C 1 |
| ATOM 1908 O O . ARG A 1 264 ? 30.940 13.307 7.174 1.00 15.19 ? 565 ARG X O 1 |
| ATOM 1909 C CB . ARG A 1 264 ? 33.480 11.529 6.251 1.00 16.27 ? 565 ARG X CB 1 |
| ATOM 1910 C CG . ARG A 1 264 ? 34.959 11.346 5.954 1.00 18.18 ? 565 ARG X CG 1 |
| ATOM 1911 C CD . ARG A 1 264 ? 35.426 9.913 6.112 1.00 18.83 ? 565 ARG X CD 1 |
| ATOM 1912 N NE . ARG A 1 264 ? 36.883 9.853 5.977 1.00 25.52 ? 565 ARG X NE 1 |
| ATOM 1913 C CZ . ARG A 1 264 ? 37.669 8.970 6.585 1.00 29.13 ? 565 ARG X CZ 1 |
| ATOM 1914 N NH1 . ARG A 1 264 ? 37.156 8.046 7.393 1.00 32.03 ? 565 ARG X NH1 1 |
| ATOM 1915 N NH2 . ARG A 1 264 ? 38.981 9.018 6.386 1.00 31.36 ? 565 ARG X NH2 1 |
| ATOM 1916 N N . ILE A 1 265 ? 30.797 12.811 4.970 1.00 14.88 ? 566 ILE X N 1 |
| ATOM 1917 C CA . ILE A 1 265 ? 29.337 12.817 4.921 1.00 14.40 ? 566 ILE X CA 1 |
| ATOM 1918 C C . ILE A 1 265 ? 28.853 11.410 5.223 1.00 14.02 ? 566 ILE X C 1 |
| ATOM 1919 O O . ILE A 1 265 ? 29.422 10.444 4.721 1.00 14.62 ? 566 ILE X O 1 |
| ATOM 1920 C CB . ILE A 1 265 ? 28.831 13.275 3.526 1.00 14.53 ? 566 ILE X CB 1 |
| ATOM 1921 C CG1 . ILE A 1 265 ? 29.035 14.780 3.389 1.00 17.37 ? 566 ILE X CG1 1 |
| ATOM 1922 C CG2 . ILE A 1 265 ? 27.359 12.901 3.301 1.00 15.81 ? 566 ILE X CG2 1 |
| ATOM 1923 C CD1 . ILE A 1 265 ? 28.785 15.306 1.995 1.00 20.14 ? 566 ILE X CD1 1 |
| ATOM 1924 N N . TYR A 1 266 ? 27.822 11.293 6.058 1.00 13.13 ? 567 TYR X N 1 |
| ATOM 1925 C CA . TYR A 1 266 ? 27.148 10.008 6.271 1.00 13.43 ? 567 TYR X CA 1 |
| ATOM 1926 C C . TYR A 1 266 ? 25.700 10.137 5.849 1.00 13.03 ? 567 TYR X C 1 |
| ATOM 1927 O O . TYR A 1 266 ? 25.048 11.126 6.206 1.00 13.67 ? 567 TYR X O 1 |
| ATOM 1928 C CB . TYR A 1 266 ? 27.210 9.606 7.744 1.00 14.16 ? 567 TYR X CB 1 |
| ATOM 1929 C CG . TYR A 1 266 ? 28.599 9.228 8.195 1.00 14.50 ? 567 TYR X CG 1 |
| ATOM 1930 C CD1 . TYR A 1 266 ? 29.580 10.211 8.436 1.00 16.14 ? 567 TYR X CD1 1 |
| ATOM 1931 C CD2 . TYR A 1 266 ? 28.947 7.886 8.384 1.00 15.55 ? 567 TYR X CD2 1 |
| ATOM 1932 C CE1 . TYR A 1 266 ? 30.861 9.854 8.842 1.00 16.06 ? 567 TYR X CE1 1 |
| ATOM 1933 C CE2 . TYR A 1 266 ? 30.234 7.527 8.802 1.00 16.66 ? 567 TYR X CE2 1 |
| ATOM 1934 C CZ . TYR A 1 266 ? 31.178 8.519 9.025 1.00 16.79 ? 567 TYR X CZ 1 |
| ATOM 1935 O OH . TYR A 1 266 ? 32.459 8.177 9.425 1.00 18.07 ? 567 TYR X OH 1 |
| ATOM 1936 N N . VAL A 1 267 ? 25.217 9.174 5.068 1.00 13.05 ? 568 VAL X N 1 |
| ATOM 1937 C CA . VAL A 1 267 ? 23.788 9.106 4.716 1.00 13.35 ? 568 VAL X CA 1 |
| ATOM 1938 C C . VAL A 1 267 ? 23.182 7.870 5.359 1.00 13.62 ? 568 VAL X C 1 |
| ATOM 1939 O O . VAL A 1 267 ? 23.815 6.810 5.356 1.00 13.92 ? 568 VAL X O 1 |
| ATOM 1940 C CB . VAL A 1 267 ? 23.528 9.101 3.179 1.00 13.81 ? 568 VAL X CB 1 |
| ATOM 1941 C CG1 . VAL A 1 267 ? 24.033 10.389 2.562 1.00 14.48 ? 568 VAL X CG1 1 |
| ATOM 1942 C CG2 . VAL A 1 267 ? 24.187 7.896 2.484 1.00 14.40 ? 568 VAL X CG2 1 |
| ATOM 1943 N N . LEU A 1 268 ? 21.979 8.013 5.920 1.00 13.04 ? 569 LEU X N 1 |
| ATOM 1944 C CA . LEU A 1 268 ? 21.384 6.926 6.683 1.00 13.35 ? 569 LEU X CA 1 |
| ATOM 1945 C C . LEU A 1 268 ? 19.992 6.612 6.196 1.00 13.07 ? 569 LEU X C 1 |
| ATOM 1946 O O . LEU A 1 268 ? 19.132 7.502 6.154 1.00 13.99 ? 569 LEU X O 1 |
| ATOM 1947 C CB . LEU A 1 268 ? 21.274 7.312 8.155 1.00 13.73 ? 569 LEU X CB 1 |
| ATOM 1948 C CG . LEU A 1 268 ? 22.563 7.473 8.949 1.00 15.88 ? 569 LEU X CG 1 |
| ATOM 1949 C CD1 . LEU A 1 268 ? 23.186 8.855 8.714 1.00 17.00 ? 569 LEU X CD1 1 |
| ATOM 1950 C CD2 . LEU A 1 268 ? 22.241 7.299 10.416 1.00 18.66 ? 569 LEU X CD2 1 |
| ATOM 1951 N N . GLY A 1 269 ? 19.759 5.344 5.862 1.00 13.21 ? 570 GLY X N 1 |
| ATOM 1952 C CA . GLY A 1 269 ? 18.402 4.894 5.553 1.00 12.33 ? 570 GLY X CA 1 |
| ATOM 1953 C C . GLY A 1 269 ? 17.784 5.559 4.335 1.00 11.81 ? 570 GLY X C 1 |
| ATOM 1954 O O . GLY A 1 269 ? 18.480 6.038 3.431 1.00 12.37 ? 570 GLY X O 1 |
| ATOM 1955 N N . GLY A 1 270 ? 16.460 5.556 4.325 1.00 11.28 ? 571 GLY X N 1 |
| ATOM 1956 C CA . GLY A 1 270 ? 15.697 6.082 3.204 1.00 11.10 ? 571 GLY X CA 1 |
| ATOM 1957 C C . GLY A 1 270 ? 14.796 5.032 2.576 1.00 11.79 ? 571 GLY X C 1 |
| ATOM 1958 O O . GLY A 1 270 ? 14.639 3.919 3.103 1.00 12.95 ? 571 GLY X O 1 |
| ATOM 1959 N N . TYR A 1 271 ? 14.209 5.403 1.450 1.00 12.03 ? 572 TYR X N 1 |
| ATOM 1960 C CA . TYR A 1 271 ? 13.300 4.528 0.720 1.00 12.35 ? 572 TYR X CA 1 |
| ATOM 1961 C C . TYR A 1 271 ? 13.762 4.533 -0.731 1.00 13.12 ? 572 TYR X C 1 |
| ATOM 1962 O O . TYR A 1 271 ? 14.191 5.567 -1.225 1.00 12.40 ? 572 TYR X O 1 |
| ATOM 1963 C CB . TYR A 1 271 ? 11.906 5.143 0.807 1.00 12.26 ? 572 TYR X CB 1 |
| ATOM 1964 C CG . TYR A 1 271 ? 10.804 4.379 0.112 1.00 12.76 ? 572 TYR X CG 1 |
| ATOM 1965 C CD1 . TYR A 1 271 ? 10.458 3.087 0.528 1.00 12.40 ? 572 TYR X CD1 1 |
| ATOM 1966 C CD2 . TYR A 1 271 ? 10.078 4.961 -0.925 1.00 13.97 ? 572 TYR X CD2 1 |
| ATOM 1967 C CE1 . TYR A 1 271 ? 9.418 2.395 -0.093 1.00 13.84 ? 572 TYR X CE1 1 |
| ATOM 1968 C CE2 . TYR A 1 271 ? 9.045 4.287 -1.543 1.00 14.39 ? 572 TYR X CE2 1 |
| ATOM 1969 C CZ . TYR A 1 271 ? 8.719 3.008 -1.128 1.00 14.28 ? 572 TYR X CZ 1 |
| ATOM 1970 O OH . TYR A 1 271 ? 7.686 2.332 -1.753 1.00 15.73 ? 572 TYR X OH 1 |
| ATOM 1971 N N . ASP A 1 272 ? 13.652 3.398 -1.419 1.00 13.96 ? 573 ASP X N 1 |
| ATOM 1972 C CA . ASP A 1 272 ? 14.058 3.362 -2.820 1.00 15.64 ? 573 ASP X CA 1 |
| ATOM 1973 C C . ASP A 1 272 ? 12.957 2.879 -3.783 1.00 16.20 ? 573 ASP X C 1 |
| ATOM 1974 O O . ASP A 1 272 ? 13.251 2.456 -4.914 1.00 17.16 ? 573 ASP X O 1 |
| ATOM 1975 C CB . ASP A 1 272 ? 15.354 2.555 -2.962 1.00 15.44 ? 573 ASP X CB 1 |
| ATOM 1976 C CG . ASP A 1 272 ? 15.156 1.076 -2.669 1.00 16.80 ? 573 ASP X CG 1 |
| ATOM 1977 O OD1 . ASP A 1 272 ? 13.992 0.680 -2.452 1.00 15.63 ? 573 ASP X OD1 1 |
| ATOM 1978 O OD2 . ASP A 1 272 ? 16.152 0.314 -2.675 1.00 18.49 ? 573 ASP X OD2 1 |
| ATOM 1979 N N . GLY A 1 273 ? 11.705 2.951 -3.347 1.00 16.29 ? 574 GLY X N 1 |
| ATOM 1980 C CA . GLY A 1 273 ? 10.583 2.501 -4.164 1.00 16.93 ? 574 GLY X CA 1 |
| ATOM 1981 C C . GLY A 1 273 ? 10.243 1.040 -3.946 1.00 16.66 ? 574 GLY X C 1 |
| ATOM 1982 O O . GLY A 1 273 ? 9.160 0.592 -4.334 1.00 17.90 ? 574 GLY X O 1 |
| ATOM 1983 N N . HIS A 1 274 ? 11.161 0.287 -3.332 1.00 15.87 ? 575 HIS X N 1 |
| ATOM 1984 C CA . HIS A 1 274 ? 10.977 -1.154 -3.135 1.00 16.07 ? 575 HIS X CA 1 |
| ATOM 1985 C C . HIS A 1 274 ? 11.235 -1.625 -1.712 1.00 15.32 ? 575 HIS X C 1 |
| ATOM 1986 O O . HIS A 1 274 ? 10.644 -2.613 -1.250 1.00 15.19 ? 575 HIS X O 1 |
| ATOM 1987 C CB . HIS A 1 274 ? 11.880 -1.931 -4.107 1.00 17.07 ? 575 HIS X CB 1 |
| ATOM 1988 C CG . HIS A 1 274 ? 11.591 -1.626 -5.543 1.00 20.83 ? 575 HIS X CG 1 |
| ATOM 1989 N ND1 . HIS A 1 274 ? 10.550 -2.207 -6.231 1.00 26.27 ? 575 HIS X ND1 1 |
| ATOM 1990 C CD2 . HIS A 1 274 ? 12.166 -0.746 -6.397 1.00 25.66 ? 575 HIS X CD2 1 |
| ATOM 1991 C CE1 . HIS A 1 274 ? 10.519 -1.725 -7.463 1.00 26.51 ? 575 HIS X CE1 1 |
| ATOM 1992 N NE2 . HIS A 1 274 ? 11.488 -0.836 -7.587 1.00 26.75 ? 575 HIS X NE2 1 |
| ATOM 1993 N N . THR A 1 275 ? 12.127 -0.914 -1.030 1.00 14.38 ? 576 THR X N 1 |
| ATOM 1994 C CA . THR A 1 275 ? 12.610 -1.306 0.300 1.00 14.62 ? 576 THR X CA 1 |
| ATOM 1995 C C . THR A 1 275 ? 12.880 -0.058 1.142 1.00 14.14 ? 576 THR X C 1 |
| ATOM 1996 O O . THR A 1 275 ? 13.046 1.065 0.610 1.00 14.26 ? 576 THR X O 1 |
| ATOM 1997 C CB . THR A 1 275 ? 13.960 -2.081 0.237 1.00 15.11 ? 576 THR X CB 1 |
| ATOM 1998 O OG1 . THR A 1 275 ? 14.968 -1.215 -0.308 1.00 15.84 ? 576 THR X OG1 1 |
| ATOM 1999 C CG2 . THR A 1 275 ? 13.864 -3.357 -0.612 1.00 16.55 ? 576 THR X CG2 1 |
| ATOM 2000 N N . PHE A 1 276 ? 12.962 -0.294 2.448 1.00 13.50 ? 577 PHE X N 1 |
| ATOM 2001 C CA . PHE A 1 276 ? 13.418 0.696 3.433 1.00 13.48 ? 577 PHE X CA 1 |
| ATOM 2002 C C . PHE A 1 276 ? 14.858 0.381 3.779 1.00 14.41 ? 577 PHE X C 1 |
| ATOM 2003 O O . PHE A 1 276 ? 15.179 -0.721 4.245 1.00 15.34 ? 577 PHE X O 1 |
| ATOM 2004 C CB . PHE A 1 276 ? 12.535 0.675 4.677 1.00 13.78 ? 577 PHE X CB 1 |
| ATOM 2005 C CG . PHE A 1 276 ? 11.146 1.141 4.403 1.00 13.23 ? 577 PHE X CG 1 |
| ATOM 2006 C CD1 . PHE A 1 276 ? 10.204 0.273 3.849 1.00 14.23 ? 577 PHE X CD1 1 |
| ATOM 2007 C CD2 . PHE A 1 276 ? 10.791 2.468 4.643 1.00 14.07 ? 577 PHE X CD2 1 |
| ATOM 2008 C CE1 . PHE A 1 276 ? 8.918 0.716 3.547 1.00 15.10 ? 577 PHE X CE1 1 |
| ATOM 2009 C CE2 . PHE A 1 276 ? 9.505 2.915 4.370 1.00 15.56 ? 577 PHE X CE2 1 |
| ATOM 2010 C CZ . PHE A 1 276 ? 8.567 2.043 3.809 1.00 15.64 ? 577 PHE X CZ 1 |
| ATOM 2011 N N . LEU A 1 277 ? 15.739 1.332 3.503 1.00 13.19 ? 578 LEU X N 1 |
| ATOM 2012 C CA . LEU A 1 277 ? 17.166 1.081 3.614 1.00 13.70 ? 578 LEU X CA 1 |
| ATOM 2013 C C . LEU A 1 277 ? 17.624 1.063 5.059 1.00 13.68 ? 578 LEU X C 1 |
| ATOM 2014 O O . LEU A 1 277 ? 17.229 1.903 5.853 1.00 13.16 ? 578 LEU X O 1 |
| ATOM 2015 C CB . LEU A 1 277 ? 17.972 2.131 2.836 1.00 13.64 ? 578 LEU X CB 1 |
| ATOM 2016 C CG . LEU A 1 277 ? 17.918 2.007 1.300 1.00 15.24 ? 578 LEU X CG 1 |
| ATOM 2017 C CD1 . LEU A 1 277 ? 16.577 2.421 0.711 1.00 16.88 ? 578 LEU X CD1 1 |
| ATOM 2018 C CD2 . LEU A 1 277 ? 19.030 2.831 0.676 1.00 18.17 ? 578 LEU X CD2 1 |
| ATOM 2019 N N . ASP A 1 278 ? 18.462 0.086 5.384 1.00 14.31 ? 579 ASP X N 1 |
| ATOM 2020 C CA . ASP A 1 278 ? 19.261 0.169 6.609 1.00 14.36 ? 579 ASP X CA 1 |
| ATOM 2021 C C . ASP A 1 278 ? 20.708 0.639 6.366 1.00 14.51 ? 579 ASP X C 1 |
| ATOM 2022 O O . ASP A 1 278 ? 21.452 0.849 7.316 1.00 15.40 ? 579 ASP X O 1 |
| ATOM 2023 C CB . ASP A 1 278 ? 19.234 -1.163 7.383 1.00 14.85 ? 579 ASP X CB 1 |
| ATOM 2024 C CG . ASP A 1 278 ? 19.718 -2.343 6.549 1.00 16.53 ? 579 ASP X CG 1 |
| ATOM 2025 O OD1 . ASP A 1 278 ? 20.181 -2.132 5.394 1.00 16.21 ? 579 ASP X OD1 1 |
| ATOM 2026 O OD2 . ASP A 1 278 ? 19.656 -3.485 7.075 1.00 17.87 ? 579 ASP X OD2 1 |
| ATOM 2027 N N . SER A 1 279 ? 21.084 0.803 5.099 1.00 13.94 ? 580 SER X N 1 |
| ATOM 2028 C CA A SER A 1 279 ? 22.444 1.154 4.692 0.50 13.86 ? 580 SER X CA 1 |
| ATOM 2029 C CA B SER A 1 279 ? 22.464 1.124 4.756 0.50 14.39 ? 580 SER X CA 1 |
| ATOM 2030 C C . SER A 1 279 ? 22.859 2.507 5.229 1.00 13.88 ? 580 SER X C 1 |
| ATOM 2031 O O . SER A 1 279 ? 22.077 3.466 5.133 1.00 14.19 ? 580 SER X O 1 |
| ATOM 2032 C CB A SER A 1 279 ? 22.519 1.215 3.159 0.50 13.70 ? 580 SER X CB 1 |
| ATOM 2033 C CB B SER A 1 279 ? 22.667 1.060 3.250 0.50 14.65 ? 580 SER X CB 1 |
| ATOM 2034 O OG A SER A 1 279 ? 23.752 1.748 2.713 0.50 13.81 ? 580 SER X OG 1 |
| ATOM 2035 O OG B SER A 1 279 ? 21.712 1.867 2.611 0.50 17.50 ? 580 SER X OG 1 |
| ATOM 2036 N N . VAL A 1 280 ? 24.077 2.582 5.766 1.00 13.57 ? 581 VAL X N 1 |
| ATOM 2037 C CA . VAL A 1 280 ? 24.709 3.852 6.067 1.00 13.52 ? 581 VAL X CA 1 |
| ATOM 2038 C C . VAL A 1 280 ? 25.922 3.941 5.163 1.00 14.16 ? 581 VAL X C 1 |
| ATOM 2039 O O . VAL A 1 280 ? 26.820 3.088 5.247 1.00 14.52 ? 581 VAL X O 1 |
| ATOM 2040 C CB . VAL A 1 280 ? 25.137 3.935 7.554 1.00 12.99 ? 581 VAL X CB 1 |
| ATOM 2041 C CG1 . VAL A 1 280 ? 25.866 5.242 7.833 1.00 14.33 ? 581 VAL X CG1 1 |
| ATOM 2042 C CG2 . VAL A 1 280 ? 23.911 3.803 8.462 1.00 13.20 ? 581 VAL X CG2 1 |
| ATOM 2043 N N . GLU A 1 281 ? 25.944 4.934 4.279 1.00 14.21 ? 582 GLU X N 1 |
| ATOM 2044 C CA . GLU A 1 281 ? 27.124 5.119 3.437 1.00 14.50 ? 582 GLU X CA 1 |
| ATOM 2045 C C . GLU A 1 281 ? 27.880 6.359 3.851 1.00 14.68 ? 582 GLU X C 1 |
| ATOM 2046 O O . GLU A 1 281 ? 27.285 7.338 4.331 1.00 14.44 ? 582 GLU X O 1 |
| ATOM 2047 C CB . GLU A 1 281 ? 26.762 5.226 1.954 1.00 14.54 ? 582 GLU X CB 1 |
| ATOM 2048 C CG . GLU A 1 281 ? 26.058 4.018 1.349 1.00 15.58 ? 582 GLU X CG 1 |
| ATOM 2049 C CD . GLU A 1 281 ? 25.863 4.164 -0.160 1.00 15.79 ? 582 GLU X CD 1 |
| ATOM 2050 O OE1 . GLU A 1 281 ? 26.871 4.310 -0.909 1.00 16.65 ? 582 GLU X OE1 1 |
| ATOM 2051 O OE2 . GLU A 1 281 ? 24.694 4.128 -0.586 1.00 15.93 ? 582 GLU X OE2 1 |
| ATOM 2052 N N . CYS A 1 282 ? 29.190 6.306 3.641 1.00 15.31 ? 583 CYS X N 1 |
| ATOM 2053 C CA . CYS A 1 282 ? 30.108 7.371 4.049 1.00 15.19 ? 583 CYS X CA 1 |
| ATOM 2054 C C . CYS A 1 282 ? 30.844 7.894 2.828 1.00 15.30 ? 583 CYS X C 1 |
| ATOM 2055 O O . CYS A 1 282 ? 31.437 7.112 2.079 1.00 14.46 ? 583 CYS X O 1 |
| ATOM 2056 C CB . CYS A 1 282 ? 31.106 6.830 5.074 1.00 15.91 ? 583 CYS X CB 1 |
| ATOM 2057 S SG . CYS A 1 282 ? 32.250 8.069 5.664 1.00 19.61 ? 583 CYS X SG 1 |
| ATOM 2058 N N . TYR A 1 283 ? 30.787 9.213 2.632 1.00 14.59 ? 584 TYR X N 1 |
| ATOM 2059 C CA . TYR A 1 283 ? 31.512 9.866 1.562 1.00 14.59 ? 584 TYR X CA 1 |
| ATOM 2060 C C . TYR A 1 283 ? 32.786 10.524 2.081 1.00 14.84 ? 584 TYR X C 1 |
| ATOM 2061 O O . TYR A 1 283 ? 32.733 11.385 2.956 1.00 14.24 ? 584 TYR X O 1 |
| ATOM 2062 C CB . TYR A 1 283 ? 30.637 10.932 0.900 1.00 14.61 ? 584 TYR X CB 1 |
| ATOM 2063 C CG . TYR A 1 283 ? 31.336 11.679 -0.225 1.00 14.55 ? 584 TYR X CG 1 |
| ATOM 2064 C CD1 . TYR A 1 283 ? 31.607 11.046 -1.442 1.00 13.47 ? 584 TYR X CD1 1 |
| ATOM 2065 C CD2 . TYR A 1 283 ? 31.706 13.020 -0.084 1.00 14.24 ? 584 TYR X CD2 1 |
| ATOM 2066 C CE1 . TYR A 1 283 ? 32.246 11.715 -2.490 1.00 13.92 ? 584 TYR X CE1 1 |
| ATOM 2067 C CE2 . TYR A 1 283 ? 32.349 13.699 -1.134 1.00 14.68 ? 584 TYR X CE2 1 |
| ATOM 2068 C CZ . TYR A 1 283 ? 32.608 13.036 -2.329 1.00 14.84 ? 584 TYR X CZ 1 |
| ATOM 2069 O OH . TYR A 1 283 ? 33.230 13.708 -3.355 1.00 16.39 ? 584 TYR X OH 1 |
| ATOM 2070 N N . ASP A 1 284 ? 33.924 10.113 1.526 1.00 15.66 ? 585 ASP X N 1 |
| ATOM 2071 C CA . ASP A 1 284 ? 35.195 10.725 1.869 1.00 16.50 ? 585 ASP X CA 1 |
| ATOM 2072 C C . ASP A 1 284 ? 35.557 11.715 0.768 1.00 16.85 ? 585 ASP X C 1 |
| ATOM 2073 O O . ASP A 1 284 ? 35.869 11.297 -0.357 1.00 16.18 ? 585 ASP X O 1 |
| ATOM 2074 C CB . ASP A 1 284 ? 36.276 9.645 1.997 1.00 16.97 ? 585 ASP X CB 1 |
| ATOM 2075 C CG . ASP A 1 284 ? 37.639 10.203 2.434 1.00 19.60 ? 585 ASP X CG 1 |
| ATOM 2076 O OD1 . ASP A 1 284 ? 37.822 11.442 2.490 1.00 20.46 ? 585 ASP X OD1 1 |
| ATOM 2077 O OD2 . ASP A 1 284 ? 38.527 9.380 2.747 1.00 23.41 ? 585 ASP X OD2 1 |
| ATOM 2078 N N . PRO A 1 285 ? 35.510 13.031 1.076 1.00 17.37 ? 586 PRO X N 1 |
| ATOM 2079 C CA . PRO A 1 285 ? 35.768 14.007 0.017 1.00 17.73 ? 586 PRO X CA 1 |
| ATOM 2080 C C . PRO A 1 285 ? 37.220 13.988 -0.453 1.00 18.52 ? 586 PRO X C 1 |
| ATOM 2081 O O . PRO A 1 285 ? 37.514 14.447 -1.553 1.00 19.00 ? 586 PRO X O 1 |
| ATOM 2082 C CB . PRO A 1 285 ? 35.419 15.350 0.680 1.00 17.51 ? 586 PRO X CB 1 |
| ATOM 2083 C CG . PRO A 1 285 ? 35.653 15.115 2.138 1.00 17.91 ? 586 PRO X CG 1 |
| ATOM 2084 C CD . PRO A 1 285 ? 35.221 13.681 2.372 1.00 17.99 ? 586 PRO X CD 1 |
| ATOM 2085 N N . ASP A 1 286 ? 38.115 13.451 0.373 1.00 19.17 ? 587 ASP X N 1 |
| ATOM 2086 C CA . ASP A 1 286 ? 39.534 13.438 0.034 1.00 20.37 ? 587 ASP X CA 1 |
| ATOM 2087 C C . ASP A 1 286 ? 39.866 12.402 -1.046 1.00 20.48 ? 587 ASP X C 1 |
| ATOM 2088 O O . ASP A 1 286 ? 40.886 12.531 -1.730 1.00 21.78 ? 587 ASP X O 1 |
| ATOM 2089 C CB . ASP A 1 286 ? 40.399 13.217 1.282 1.00 20.96 ? 587 ASP X CB 1 |
| ATOM 2090 C CG . ASP A 1 286 ? 40.414 14.422 2.230 1.00 23.76 ? 587 ASP X CG 1 |
| ATOM 2091 O OD1 . ASP A 1 286 ? 39.696 15.431 2.008 1.00 25.95 ? 587 ASP X OD1 1 |
| ATOM 2092 O OD2 . ASP A 1 286 ? 41.178 14.356 3.224 1.00 28.41 ? 587 ASP X OD2 1 |
| ATOM 2093 N N . THR A 1 287 ? 39.012 11.380 -1.183 1.00 19.65 ? 588 THR X N 1 |
| ATOM 2094 C CA . THR A 1 287 ? 39.149 10.337 -2.209 1.00 19.62 ? 588 THR X CA 1 |
| ATOM 2095 C C . THR A 1 287 ? 38.004 10.342 -3.237 1.00 18.85 ? 588 THR X C 1 |
| ATOM 2096 O O . THR A 1 287 ? 38.075 9.648 -4.255 1.00 19.65 ? 588 THR X O 1 |
| ATOM 2097 C CB . THR A 1 287 ? 39.196 8.924 -1.574 1.00 19.81 ? 588 THR X CB 1 |
| ATOM 2098 O OG1 . THR A 1 287 ? 38.009 8.705 -0.799 1.00 21.46 ? 588 THR X OG1 1 |
| ATOM 2099 C CG2 . THR A 1 287 ? 40.396 8.802 -0.671 1.00 21.08 ? 588 THR X CG2 1 |
| ATOM 2100 N N . ASP A 1 288 ? 36.949 11.108 -2.952 1.00 17.91 ? 589 ASP X N 1 |
| ATOM 2101 C CA . ASP A 1 288 ? 35.726 11.152 -3.773 1.00 17.85 ? 589 ASP X CA 1 |
| ATOM 2102 C C . ASP A 1 288 ? 35.148 9.750 -3.953 1.00 17.14 ? 589 ASP X C 1 |
| ATOM 2103 O O . ASP A 1 288 ? 34.858 9.304 -5.064 1.00 17.25 ? 589 ASP X O 1 |
| ATOM 2104 C CB . ASP A 1 288 ? 35.966 11.861 -5.122 1.00 18.11 ? 589 ASP X CB 1 |
| ATOM 2105 C CG . ASP A 1 288 ? 34.691 11.994 -5.966 1.00 19.14 ? 589 ASP X CG 1 |
| ATOM 2106 O OD1 . ASP A 1 288 ? 33.602 12.253 -5.400 1.00 18.92 ? 589 ASP X OD1 1 |
| ATOM 2107 O OD2 . ASP A 1 288 ? 34.790 11.856 -7.211 1.00 19.19 ? 589 ASP X OD2 1 |
| ATOM 2108 N N . THR A 1 289 ? 35.023 9.039 -2.835 1.00 17.21 ? 590 THR X N 1 |
| ATOM 2109 C CA . THR A 1 289 ? 34.442 7.709 -2.867 1.00 17.27 ? 590 THR X CA 1 |
| ATOM 2110 C C . THR A 1 289 ? 33.445 7.526 -1.734 1.00 16.90 ? 590 THR X C 1 |
| ATOM 2111 O O . THR A 1 289 ? 33.607 8.088 -0.652 1.00 17.33 ? 590 THR X O 1 |
| ATOM 2112 C CB . THR A 1 289 ? 35.509 6.602 -2.748 1.00 17.64 ? 590 THR X CB 1 |
| ATOM 2113 O OG1 . THR A 1 289 ? 36.236 6.782 -1.531 1.00 19.92 ? 590 THR X OG1 1 |
| ATOM 2114 C CG2 . THR A 1 289 ? 36.480 6.616 -3.934 1.00 19.20 ? 590 THR X CG2 1 |
| ATOM 2115 N N . TRP A 1 290 ? 32.420 6.726 -2.005 1.00 16.75 ? 591 TRP X N 1 |
| ATOM 2116 C CA . TRP A 1 290 ? 31.466 6.291 -0.997 1.00 16.70 ? 591 TRP X CA 1 |
| ATOM 2117 C C . TRP A 1 290 ? 31.792 4.855 -0.587 1.00 17.38 ? 591 TRP X C 1 |
| ATOM 2118 O O . TRP A 1 290 ? 32.293 4.067 -1.403 1.00 17.68 ? 591 TRP X O 1 |
| ATOM 2119 C CB . TRP A 1 290 ? 30.051 6.313 -1.584 1.00 16.46 ? 591 TRP X CB 1 |
| ATOM 2120 C CG . TRP A 1 290 ? 29.497 7.676 -1.840 1.00 15.19 ? 591 TRP X CG 1 |
| ATOM 2121 C CD1 . TRP A 1 290 ? 29.612 8.424 -2.985 1.00 15.38 ? 591 TRP X CD1 1 |
| ATOM 2122 C CD2 . TRP A 1 290 ? 28.684 8.446 -0.936 1.00 14.73 ? 591 TRP X CD2 1 |
| ATOM 2123 N NE1 . TRP A 1 290 ? 28.950 9.633 -2.829 1.00 14.76 ? 591 TRP X NE1 1 |
| ATOM 2124 C CE2 . TRP A 1 290 ? 28.363 9.664 -1.588 1.00 14.41 ? 591 TRP X CE2 1 |
| ATOM 2125 C CE3 . TRP A 1 290 ? 28.208 8.232 0.367 1.00 15.44 ? 591 TRP X CE3 1 |
| ATOM 2126 C CZ2 . TRP A 1 290 ? 27.583 10.658 -0.978 1.00 14.17 ? 591 TRP X CZ2 1 |
| ATOM 2127 C CZ3 . TRP A 1 290 ? 27.443 9.225 0.974 1.00 14.06 ? 591 TRP X CZ3 1 |
| ATOM 2128 C CH2 . TRP A 1 290 ? 27.138 10.424 0.303 1.00 15.57 ? 591 TRP X CH2 1 |
| ATOM 2129 N N . SER A 1 291 ? 31.515 4.515 0.672 1.00 17.65 ? 592 SER X N 1 |
| ATOM 2130 C CA . SER A 1 291 ? 31.526 3.107 1.088 1.00 18.29 ? 592 SER X CA 1 |
| ATOM 2131 C C . SER A 1 291 ? 30.421 2.867 2.099 1.00 18.25 ? 592 SER X C 1 |
| ATOM 2132 O O . SER A 1 291 ? 29.990 3.793 2.783 1.00 17.42 ? 592 SER X O 1 |
| ATOM 2133 C CB . SER A 1 291 ? 32.873 2.722 1.694 1.00 19.40 ? 592 SER X CB 1 |
| ATOM 2134 O OG . SER A 1 291 ? 33.117 3.461 2.883 1.00 21.97 ? 592 SER X OG 1 |
| ATOM 2135 N N . GLU A 1 292 ? 29.949 1.629 2.184 1.00 17.88 ? 593 GLU X N 1 |
| ATOM 2136 C CA . GLU A 1 292 ? 28.942 1.294 3.174 1.00 18.85 ? 593 GLU X CA 1 |
| ATOM 2137 C C . GLU A 1 292 ? 29.678 0.905 4.448 1.00 18.67 ? 593 GLU X C 1 |
| ATOM 2138 O O . GLU A 1 292 ? 30.412 -0.097 4.484 1.00 19.89 ? 593 GLU X O 1 |
| ATOM 2139 C CB . GLU A 1 292 ? 28.038 0.161 2.678 1.00 18.65 ? 593 GLU X CB 1 |
| ATOM 2140 C CG . GLU A 1 292 ? 26.857 -0.112 3.593 1.00 21.59 ? 593 GLU X CG 1 |
| ATOM 2141 C CD . GLU A 1 292 ? 25.971 -1.231 3.090 1.00 24.47 ? 593 GLU X CD 1 |
| ATOM 2142 O OE1 . GLU A 1 292 ? 26.493 -2.318 2.757 1.00 26.80 ? 593 GLU X OE1 1 |
| ATOM 2143 O OE2 . GLU A 1 292 ? 24.747 -1.030 3.030 1.00 26.52 ? 593 GLU X OE2 1 |
| ATOM 2144 N N . VAL A 1 293 ? 29.506 1.705 5.492 1.00 18.37 ? 594 VAL X N 1 |
| ATOM 2145 C CA . VAL A 1 293 ? 30.331 1.529 6.684 1.00 18.24 ? 594 VAL X CA 1 |
| ATOM 2146 C C . VAL A 1 293 ? 29.635 0.748 7.771 1.00 18.00 ? 594 VAL X C 1 |
| ATOM 2147 O O . VAL A 1 293 ? 30.285 0.156 8.628 1.00 18.68 ? 594 VAL X O 1 |
| ATOM 2148 C CB . VAL A 1 293 ? 30.876 2.866 7.246 1.00 18.43 ? 594 VAL X CB 1 |
| ATOM 2149 C CG1 . VAL A 1 293 ? 31.898 3.460 6.275 1.00 18.38 ? 594 VAL X CG1 1 |
| ATOM 2150 C CG2 . VAL A 1 293 ? 29.739 3.845 7.554 1.00 18.73 ? 594 VAL X CG2 1 |
| ATOM 2151 N N . THR A 1 294 ? 28.310 0.757 7.739 1.00 17.04 ? 595 THR X N 1 |
| ATOM 2152 C CA . THR A 1 294 ? 27.522 0.057 8.743 1.00 17.02 ? 595 THR X CA 1 |
| ATOM 2153 C C . THR A 1 294 ? 26.100 -0.027 8.231 1.00 16.82 ? 595 THR X C 1 |
| ATOM 2154 O O . THR A 1 294 ? 25.788 0.476 7.144 1.00 16.62 ? 595 THR X O 1 |
| ATOM 2155 C CB . THR A 1 294 ? 27.574 0.742 10.150 1.00 17.05 ? 595 THR X CB 1 |
| ATOM 2156 O OG1 . THR A 1 294 ? 26.989 -0.120 11.136 1.00 17.50 ? 595 THR X OG1 1 |
| ATOM 2157 C CG2 . THR A 1 294 ? 26.844 2.100 10.159 1.00 17.17 ? 595 THR X CG2 1 |
| ATOM 2158 N N . ARG A 1 295 ? 25.255 -0.705 8.997 1.00 16.73 ? 596 ARG X N 1 |
| ATOM 2159 C CA . ARG A 1 295 ? 23.836 -0.718 8.744 1.00 17.07 ? 596 ARG X CA 1 |
| ATOM 2160 C C . ARG A 1 295 ? 23.132 -0.403 10.048 1.00 16.63 ? 596 ARG X C 1 |
| ATOM 2161 O O . ARG A 1 295 ? 23.601 -0.779 11.121 1.00 17.33 ? 596 ARG X O 1 |
| ATOM 2162 C CB . ARG A 1 295 ? 23.398 -2.088 8.227 1.00 17.56 ? 596 ARG X CB 1 |
| ATOM 2163 C CG . ARG A 1 295 ? 23.859 -2.305 6.808 1.00 18.80 ? 596 ARG X CG 1 |
| ATOM 2164 C CD . ARG A 1 295 ? 23.414 -3.613 6.235 1.00 19.93 ? 596 ARG X CD 1 |
| ATOM 2165 N NE . ARG A 1 295 ? 24.050 -3.777 4.933 1.00 22.45 ? 596 ARG X NE 1 |
| ATOM 2166 C CZ . ARG A 1 295 ? 24.194 -4.939 4.302 1.00 21.68 ? 596 ARG X CZ 1 |
| ATOM 2167 N NH1 . ARG A 1 295 ? 23.725 -6.055 4.842 1.00 21.96 ? 596 ARG X NH1 1 |
| ATOM 2168 N NH2 . ARG A 1 295 ? 24.806 -4.965 3.123 1.00 23.01 ? 596 ARG X NH2 1 |
| ATOM 2169 N N . MET A 1 296 ? 22.027 0.326 9.946 1.00 16.47 ? 597 MET X N 1 |
| ATOM 2170 C CA A MET A 1 296 ? 21.157 0.582 11.079 0.50 17.64 ? 597 MET X CA 1 |
| ATOM 2171 C CA B MET A 1 296 ? 21.168 0.572 11.095 0.50 15.71 ? 597 MET X CA 1 |
| ATOM 2172 C C . MET A 1 296 ? 20.574 -0.743 11.567 1.00 16.32 ? 597 MET X C 1 |
| ATOM 2173 O O . MET A 1 296 ? 20.590 -1.743 10.828 1.00 16.10 ? 597 MET X O 1 |
| ATOM 2174 C CB A MET A 1 296 ? 20.054 1.548 10.652 0.50 17.22 ? 597 MET X CB 1 |
| ATOM 2175 C CB B MET A 1 296 ? 20.054 1.553 10.742 0.50 15.65 ? 597 MET X CB 1 |
| ATOM 2176 C CG A MET A 1 296 ? 20.618 2.770 9.917 0.50 18.99 ? 597 MET X CG 1 |
| ATOM 2177 C CG B MET A 1 296 ? 20.557 2.978 10.583 0.50 15.09 ? 597 MET X CG 1 |
| ATOM 2178 S SD A MET A 1 296 ? 19.403 3.834 9.135 0.50 22.20 ? 597 MET X SD 1 |
| ATOM 2179 S SD B MET A 1 296 ? 19.265 4.187 10.255 0.50 13.93 ? 597 MET X SD 1 |
| ATOM 2180 C CE A MET A 1 296 ? 18.687 4.596 10.579 0.50 22.38 ? 597 MET X CE 1 |
| ATOM 2181 C CE B MET A 1 296 ? 18.498 3.526 8.762 0.50 16.06 ? 597 MET X CE 1 |
| ATOM 2182 N N . THR A 1 297 ? 20.058 -0.757 12.802 1.00 16.72 ? 598 THR X N 1 |
| ATOM 2183 C CA . THR A 1 297 ? 19.491 -1.985 13.377 1.00 17.37 ? 598 THR X CA 1 |
| ATOM 2184 C C . THR A 1 297 ? 18.254 -2.477 12.624 1.00 16.88 ? 598 THR X C 1 |
| ATOM 2185 O O . THR A 1 297 ? 17.886 -3.660 12.711 1.00 17.56 ? 598 THR X O 1 |
| ATOM 2186 C CB . THR A 1 297 ? 19.166 -1.825 14.884 1.00 17.93 ? 598 THR X CB 1 |
| ATOM 2187 O OG1 . THR A 1 297 ? 18.275 -0.719 15.062 1.00 19.80 ? 598 THR X OG1 1 |
| ATOM 2188 C CG2 . THR A 1 297 ? 20.437 -1.582 15.695 1.00 19.41 ? 598 THR X CG2 1 |
| ATOM 2189 N N . SER A 1 298 ? 17.617 -1.572 11.884 1.00 16.21 ? 599 SER X N 1 |
| ATOM 2190 C CA . SER A 1 298 ? 16.505 -1.926 11.009 1.00 15.92 ? 599 SER X CA 1 |
| ATOM 2191 C C . SER A 1 298 ? 16.339 -0.869 9.922 1.00 14.85 ? 599 SER X C 1 |
| ATOM 2192 O O . SER A 1 298 ? 16.770 0.276 10.090 1.00 15.53 ? 599 SER X O 1 |
| ATOM 2193 C CB . SER A 1 298 ? 15.212 -2.098 11.820 1.00 16.57 ? 599 SER X CB 1 |
| ATOM 2194 O OG . SER A 1 298 ? 14.914 -0.929 12.564 1.00 17.92 ? 599 SER X OG 1 |
| ATOM 2195 N N . GLY A 1 299 ? 15.736 -1.266 8.810 1.00 14.18 ? 600 GLY X N 1 |
| ATOM 2196 C CA . GLY A 1 299 ? 15.500 -0.347 7.702 1.00 13.69 ? 600 GLY X CA 1 |
| ATOM 2197 C C . GLY A 1 299 ? 14.442 0.662 8.084 1.00 13.16 ? 600 GLY X C 1 |
| ATOM 2198 O O . GLY A 1 299 ? 13.459 0.320 8.741 1.00 13.47 ? 600 GLY X O 1 |
| ATOM 2199 N N . ARG A 1 300 ? 14.637 1.909 7.662 1.00 12.67 ? 601 ARG X N 1 |
| ATOM 2200 C CA . ARG A 1 300 ? 13.663 2.976 7.967 1.00 12.62 ? 601 ARG X CA 1 |
| ATOM 2201 C C . ARG A 1 300 ? 13.924 4.182 7.089 1.00 12.92 ? 601 ARG X C 1 |
| ATOM 2202 O O . ARG A 1 300 ? 15.047 4.418 6.659 1.00 13.84 ? 601 ARG X O 1 |
| ATOM 2203 C CB . ARG A 1 300 ? 13.754 3.378 9.444 1.00 13.34 ? 601 ARG X CB 1 |
| ATOM 2204 C CG . ARG A 1 300 ? 15.114 3.868 9.853 1.00 14.72 ? 601 ARG X CG 1 |
| ATOM 2205 C CD . ARG A 1 300 ? 15.275 3.938 11.362 1.00 17.31 ? 601 ARG X CD 1 |
| ATOM 2206 N NE . ARG A 1 300 ? 15.681 2.645 11.919 1.00 17.49 ? 601 ARG X NE 1 |
| ATOM 2207 C CZ . ARG A 1 300 ? 16.377 2.494 13.043 1.00 18.60 ? 601 ARG X CZ 1 |
| ATOM 2208 N NH1 . ARG A 1 300 ? 16.768 3.552 13.757 1.00 18.98 ? 601 ARG X NH1 1 |
| ATOM 2209 N NH2 . ARG A 1 300 ? 16.690 1.274 13.447 1.00 18.93 ? 601 ARG X NH2 1 |
| ATOM 2210 N N . SER A 1 301 ? 12.865 4.938 6.810 1.00 12.49 ? 602 SER X N 1 |
| ATOM 2211 C CA . SER A 1 301 ? 13.018 6.232 6.125 1.00 12.19 ? 602 SER X CA 1 |
| ATOM 2212 C C . SER A 1 301 ? 12.648 7.394 7.039 1.00 12.54 ? 602 SER X C 1 |
| ATOM 2213 O O . SER A 1 301 ? 12.066 7.196 8.097 1.00 12.80 ? 602 SER X O 1 |
| ATOM 2214 C CB . SER A 1 301 ? 12.114 6.296 4.901 1.00 12.14 ? 602 SER X CB 1 |
| ATOM 2215 O OG . SER A 1 301 ? 10.756 6.296 5.315 1.00 13.29 ? 602 SER X OG 1 |
| ATOM 2216 N N . GLY A 1 302 ? 12.984 8.612 6.625 1.00 12.17 ? 603 GLY X N 1 |
| ATOM 2217 C CA . GLY A 1 302 ? 12.479 9.802 7.321 1.00 13.31 ? 603 GLY X CA 1 |
| ATOM 2218 C C . GLY A 1 302 ? 13.045 10.010 8.720 1.00 13.30 ? 603 GLY X C 1 |
| ATOM 2219 O O . GLY A 1 302 ? 12.358 10.544 9.618 1.00 13.69 ? 603 GLY X O 1 |
| ATOM 2220 N N . VAL A 1 303 ? 14.292 9.579 8.926 1.00 14.11 ? 604 VAL X N 1 |
| ATOM 2221 C CA . VAL A 1 303 ? 14.958 9.764 10.219 1.00 14.45 ? 604 VAL X CA 1 |
| ATOM 2222 C C . VAL A 1 303 ? 15.462 11.191 10.404 1.00 15.20 ? 604 VAL X C 1 |
| ATOM 2223 O O . VAL A 1 303 ? 15.733 11.905 9.419 1.00 15.44 ? 604 VAL X O 1 |
| ATOM 2224 C CB . VAL A 1 303 ? 16.161 8.806 10.392 1.00 14.71 ? 604 VAL X CB 1 |
| ATOM 2225 C CG1 . VAL A 1 303 ? 15.748 7.365 10.191 1.00 15.61 ? 604 VAL X CG1 1 |
| ATOM 2226 C CG2 . VAL A 1 303 ? 17.306 9.183 9.438 1.00 17.35 ? 604 VAL X CG2 1 |
| ATOM 2227 N N . GLY A 1 304 ? 15.583 11.595 11.662 1.00 14.17 ? 605 GLY X N 1 |
| ATOM 2228 C CA . GLY A 1 304 ? 16.316 12.822 12.010 1.00 15.04 ? 605 GLY X CA 1 |
| ATOM 2229 C C . GLY A 1 304 ? 17.698 12.409 12.466 1.00 15.81 ? 605 GLY X C 1 |
| ATOM 2230 O O . GLY A 1 304 ? 17.848 11.418 13.177 1.00 16.64 ? 605 GLY X O 1 |
| ATOM 2231 N N . VAL A 1 305 ? 18.713 13.143 12.031 1.00 15.31 ? 606 VAL X N 1 |
| ATOM 2232 C CA A VAL A 1 305 ? 20.108 12.781 12.312 0.50 15.67 ? 606 VAL X CA 1 |
| ATOM 2233 C CA B VAL A 1 305 ? 20.087 12.775 12.349 0.50 15.68 ? 606 VAL X CA 1 |
| ATOM 2234 C C . VAL A 1 305 ? 20.935 14.009 12.618 1.00 15.64 ? 606 VAL X C 1 |
| ATOM 2235 O O . VAL A 1 305 ? 20.754 15.058 11.984 1.00 16.22 ? 606 VAL X O 1 |
| ATOM 2236 C CB A VAL A 1 305 ? 20.782 12.030 11.138 0.50 16.01 ? 606 VAL X CB 1 |
| ATOM 2237 C CB B VAL A 1 305 ? 20.700 11.839 11.261 0.50 16.15 ? 606 VAL X CB 1 |
| ATOM 2238 C CG1 A VAL A 1 305 ? 20.081 10.707 10.859 0.50 15.29 ? 606 VAL X CG1 1 |
| ATOM 2239 C CG1 B VAL A 1 305 ? 20.588 12.441 9.883 0.50 16.65 ? 606 VAL X CG1 1 |
| ATOM 2240 C CG2 A VAL A 1 305 ? 20.833 12.897 9.893 0.50 16.67 ? 606 VAL X CG2 1 |
| ATOM 2241 C CG2 B VAL A 1 305 ? 22.146 11.462 11.580 0.50 15.09 ? 606 VAL X CG2 1 |
| ATOM 2242 N N . ALA A 1 306 ? 21.839 13.874 13.587 1.00 15.11 ? 607 ALA X N 1 |
| ATOM 2243 C CA . ALA A 1 306 ? 22.757 14.938 13.923 1.00 15.24 ? 607 ALA X CA 1 |
| ATOM 2244 C C . ALA A 1 306 ? 23.948 14.365 14.675 1.00 15.94 ? 607 ALA X C 1 |
| ATOM 2245 O O . ALA A 1 306 ? 23.914 13.217 15.131 1.00 15.78 ? 607 ALA X O 1 |
| ATOM 2246 C CB . ALA A 1 306 ? 22.069 16.011 14.753 1.00 15.87 ? 607 ALA X CB 1 |
| ATOM 2247 N N . VAL A 1 307 ? 24.989 15.174 14.815 1.00 15.95 ? 608 VAL X N 1 |
| ATOM 2248 C CA . VAL A 1 307 ? 26.243 14.733 15.406 1.00 16.64 ? 608 VAL X CA 1 |
| ATOM 2249 C C . VAL A 1 307 ? 26.613 15.643 16.570 1.00 16.64 ? 608 VAL X C 1 |
| ATOM 2250 O O . VAL A 1 307 ? 26.596 16.876 16.435 1.00 16.56 ? 608 VAL X O 1 |
| ATOM 2251 C CB . VAL A 1 307 ? 27.391 14.781 14.370 1.00 17.00 ? 608 VAL X CB 1 |
| ATOM 2252 C CG1 . VAL A 1 307 ? 28.743 14.582 15.046 1.00 17.06 ? 608 VAL X CG1 1 |
| ATOM 2253 C CG2 . VAL A 1 307 ? 27.192 13.718 13.312 1.00 18.70 ? 608 VAL X CG2 1 |
| ATOM 2254 N N . THR A 1 308 ? 26.964 15.030 17.699 1.00 17.00 ? 609 THR X N 1 |
| ATOM 2255 C CA . THR A 1 308 ? 27.526 15.775 18.830 1.00 18.33 ? 609 THR X CA 1 |
| ATOM 2256 C C . THR A 1 308 ? 28.341 14.863 19.743 1.00 18.31 ? 609 THR X C 1 |
| ATOM 2257 O O . THR A 1 308 ? 28.208 13.637 19.674 1.00 18.42 ? 609 THR X O 1 |
| ATOM 2258 C CB . THR A 1 308 ? 26.451 16.555 19.638 1.00 18.57 ? 609 THR X CB 1 |
| ATOM 2259 O OG1 . THR A 1 308 ? 27.100 17.453 20.556 1.00 20.66 ? 609 THR X OG1 1 |
| ATOM 2260 C CG2 . THR A 1 308 ? 25.518 15.634 20.416 1.00 19.09 ? 609 THR X CG2 1 |
| ATOM 2261 O OXT . THR A 1 308 ? 29.164 15.339 20.544 1.00 19.47 ? 609 THR X OXT 1 |
| ATOM 2262 N N . ALA B 2 1 ? -14.410 10.069 4.718 1.00 17.55 ? 69 ALA P N 1 |
| ATOM 2263 C CA . ALA B 2 1 ? -15.770 9.613 5.159 1.00 16.37 ? 69 ALA P CA 1 |
| ATOM 2264 C C . ALA B 2 1 ? -16.116 8.219 4.639 1.00 15.80 ? 69 ALA P C 1 |
| ATOM 2265 O O . ALA B 2 1 ? -17.042 7.579 5.141 1.00 15.22 ? 69 ALA P O 1 |
| ATOM 2266 C CB . ALA B 2 1 ? -16.848 10.604 4.719 1.00 17.18 ? 69 ALA P CB 1 |
| ATOM 2267 N N . PHE B 2 2 ? -15.363 7.759 3.639 1.00 15.26 ? 70 PHE P N 1 |
| ATOM 2268 C CA . PHE B 2 2 ? -15.661 6.497 2.967 1.00 15.28 ? 70 PHE P CA 1 |
| ATOM 2269 C C . PHE B 2 2 ? -14.718 5.348 3.324 1.00 15.19 ? 70 PHE P C 1 |
| ATOM 2270 O O . PHE B 2 2 ? -14.768 4.296 2.687 1.00 15.14 ? 70 PHE P O 1 |
| ATOM 2271 C CB . PHE B 2 2 ? -15.639 6.717 1.453 1.00 15.23 ? 70 PHE P CB 1 |
| ATOM 2272 C CG . PHE B 2 2 ? -16.764 7.579 0.952 1.00 14.48 ? 70 PHE P CG 1 |
| ATOM 2273 C CD1 . PHE B 2 2 ? -16.615 8.959 0.861 1.00 15.96 ? 70 PHE P CD1 1 |
| ATOM 2274 C CD2 . PHE B 2 2 ? -17.973 7.009 0.577 1.00 15.40 ? 70 PHE P CD2 1 |
| ATOM 2275 C CE1 . PHE B 2 2 ? -17.655 9.757 0.391 1.00 14.76 ? 70 PHE P CE1 1 |
| ATOM 2276 C CE2 . PHE B 2 2 ? -19.027 7.811 0.109 1.00 15.43 ? 70 PHE P CE2 1 |
| ATOM 2277 C CZ . PHE B 2 2 ? -18.861 9.185 0.019 1.00 15.29 ? 70 PHE P CZ 1 |
| ATOM 2278 N N . PHE B 2 3 ? -13.885 5.538 4.347 1.00 13.94 ? 71 PHE P N 1 |
| ATOM 2279 C CA . PHE B 2 3 ? -12.903 4.518 4.759 1.00 14.14 ? 71 PHE P CA 1 |
| ATOM 2280 C C . PHE B 2 3 ? -12.055 4.019 3.587 1.00 14.10 ? 71 PHE P C 1 |
| ATOM 2281 O O . PHE B 2 3 ? -11.873 2.819 3.385 1.00 14.63 ? 71 PHE P O 1 |
| ATOM 2282 C CB . PHE B 2 3 ? -13.584 3.370 5.518 1.00 14.14 ? 71 PHE P CB 1 |
| ATOM 2283 C CG . PHE B 2 3 ? -14.347 3.843 6.719 1.00 14.57 ? 71 PHE P CG 1 |
| ATOM 2284 C CD1 . PHE B 2 3 ? -15.703 4.155 6.618 1.00 14.31 ? 71 PHE P CD1 1 |
| ATOM 2285 C CD2 . PHE B 2 3 ? -13.698 4.020 7.956 1.00 15.46 ? 71 PHE P CD2 1 |
| ATOM 2286 C CE1 . PHE B 2 3 ? -16.417 4.634 7.742 1.00 16.29 ? 71 PHE P CE1 1 |
| ATOM 2287 C CE2 . PHE B 2 3 ? -14.407 4.496 9.068 1.00 16.07 ? 71 PHE P CE2 1 |
| ATOM 2288 C CZ . PHE B 2 3 ? -15.750 4.798 8.955 1.00 15.64 ? 71 PHE P CZ 1 |
| ATOM 2289 N N . ALA B 2 4 ? -11.518 4.968 2.832 1.00 14.69 ? 72 ALA P N 1 |
| ATOM 2290 C CA . ALA B 2 4 ? -10.722 4.673 1.662 1.00 14.99 ? 72 ALA P CA 1 |
| ATOM 2291 C C . ALA B 2 4 ? -9.447 3.912 2.004 1.00 14.94 ? 72 ALA P C 1 |
| ATOM 2292 O O . ALA B 2 4 ? -8.876 4.073 3.082 1.00 15.21 ? 72 ALA P O 1 |
| ATOM 2293 C CB . ALA B 2 4 ? -10.376 5.980 0.934 1.00 15.80 ? 72 ALA P CB 1 |
| ATOM 2294 N N . GLN B 2 5 ? -9.005 3.096 1.059 1.00 15.49 ? 73 GLN P N 1 |
| ATOM 2295 C CA . GLN B 2 5 ? -7.713 2.421 1.148 1.00 15.74 ? 73 GLN P CA 1 |
| ATOM 2296 C C . GLN B 2 5 ? -6.579 3.445 1.288 1.00 16.02 ? 73 GLN P C 1 |
| ATOM 2297 O O . GLN B 2 5 ? -6.672 4.568 0.761 1.00 16.08 ? 73 GLN P O 1 |
| ATOM 2298 C CB . GLN B 2 5 ? -7.501 1.558 -0.107 1.00 15.42 ? 73 GLN P CB 1 |
| ATOM 2299 C CG . GLN B 2 5 ? -6.222 0.742 -0.181 1.00 15.41 ? 73 GLN P CG 1 |
| ATOM 2300 C CD . GLN B 2 5 ? -6.036 -0.181 1.020 1.00 14.57 ? 73 GLN P CD 1 |
| ATOM 2301 O OE1 . GLN B 2 5 ? -5.720 0.275 2.122 1.00 13.59 ? 73 GLN P OE1 1 |
| ATOM 2302 N NE2 . GLN B 2 5 ? -6.209 -1.488 0.804 1.00 14.06 ? 73 GLN P NE2 1 |
| ATOM 2303 N N . LEU B 2 6 ? -5.525 3.051 1.999 1.00 16.51 ? 74 LEU P N 1 |
| ATOM 2304 C CA . LEU B 2 6 ? -4.339 3.903 2.140 1.00 18.01 ? 74 LEU P CA 1 |
| ATOM 2305 C C . LEU B 2 6 ? -3.588 4.049 0.818 1.00 18.44 ? 74 LEU P C 1 |
| ATOM 2306 O O . LEU B 2 6 ? -3.612 3.149 -0.029 1.00 18.96 ? 74 LEU P O 1 |
| ATOM 2307 C CB . LEU B 2 6 ? -3.377 3.313 3.164 1.00 18.29 ? 74 LEU P CB 1 |
| ATOM 2308 C CG . LEU B 2 6 ? -3.931 2.963 4.539 1.00 20.86 ? 74 LEU P CG 1 |
| ATOM 2309 C CD1 . LEU B 2 6 ? -2.971 1.998 5.234 1.00 22.44 ? 74 LEU P CD1 1 |
| ATOM 2310 C CD2 . LEU B 2 6 ? -4.125 4.214 5.356 1.00 22.88 ? 74 LEU P CD2 1 |
| ATOM 2311 N N . GLN B 2 7 ? -2.901 5.186 0.679 1.00 19.14 ? 75 GLN P N 1 |
| ATOM 2312 C CA A GLN B 2 7 ? -2.105 5.479 -0.510 0.50 20.04 ? 75 GLN P CA 1 |
| ATOM 2313 C CA B GLN B 2 7 ? -2.107 5.480 -0.510 0.50 20.04 ? 75 GLN P CA 1 |
| ATOM 2314 C C . GLN B 2 7 ? -0.632 5.564 -0.133 1.00 20.10 ? 75 GLN P C 1 |
| ATOM 2315 O O . GLN B 2 7 ? -0.289 6.104 0.924 1.00 20.72 ? 75 GLN P O 1 |
| ATOM 2316 C CB A GLN B 2 7 ? -2.550 6.799 -1.147 0.50 20.56 ? 75 GLN P CB 1 |
| ATOM 2317 C CB B GLN B 2 7 ? -2.555 6.802 -1.134 0.50 20.53 ? 75 GLN P CB 1 |
| ATOM 2318 C CG A GLN B 2 7 ? -3.855 6.710 -1.936 0.50 21.94 ? 75 GLN P CG 1 |
| ATOM 2319 C CG B GLN B 2 7 ? -3.953 6.764 -1.736 0.50 21.95 ? 75 GLN P CG 1 |
| ATOM 2320 C CD A GLN B 2 7 ? -3.688 6.037 -3.287 0.50 23.87 ? 75 GLN P CD 1 |
| ATOM 2321 C CD B GLN B 2 7 ? -4.459 8.141 -2.109 0.50 23.46 ? 75 GLN P CD 1 |
| ATOM 2322 O OE1 A GLN B 2 7 ? -2.755 6.339 -4.039 0.50 24.72 ? 75 GLN P OE1 1 |
| ATOM 2323 O OE1 B GLN B 2 7 ? -4.281 8.590 -3.240 0.50 24.10 ? 75 GLN P OE1 1 |
| ATOM 2324 N NE2 A GLN B 2 7 ? -4.594 5.119 -3.603 0.50 24.38 ? 75 GLN P NE2 1 |
| ATOM 2325 N NE2 B GLN B 2 7 ? -5.082 8.827 -1.151 0.50 24.80 ? 75 GLN P NE2 1 |
| ATOM 2326 N N . LEU B 2 8 ? 0.218 5.028 -1.006 1.00 20.35 ? 76 LEU P N 1 |
| ATOM 2327 C CA . LEU B 2 8 ? 1.668 4.997 -0.840 1.00 20.28 ? 76 LEU P CA 1 |
| ATOM 2328 C C . LEU B 2 8 ? 2.293 6.340 -1.203 1.00 19.47 ? 76 LEU P C 1 |
| ATOM 2329 O O . LEU B 2 8 ? 1.984 6.912 -2.247 1.00 20.05 ? 76 LEU P O 1 |
| ATOM 2330 C CB . LEU B 2 8 ? 2.244 3.883 -1.737 1.00 21.01 ? 76 LEU P CB 1 |
| ATOM 2331 C CG . LEU B 2 8 ? 3.714 3.726 -2.163 1.00 22.59 ? 76 LEU P CG 1 |
| ATOM 2332 C CD1 . LEU B 2 8 ? 4.121 4.669 -3.318 1.00 26.08 ? 76 LEU P CD1 1 |
| ATOM 2333 C CD2 . LEU B 2 8 ? 4.679 3.781 -0.979 1.00 25.49 ? 76 LEU P CD2 1 |
| ATOM 2334 N N . ASP B 2 9 ? 3.166 6.844 -0.328 1.00 17.83 ? 77 ASP P N 1 |
| ATOM 2335 C CA . ASP B 2 9 ? 3.960 8.028 -0.641 1.00 16.74 ? 77 ASP P CA 1 |
| ATOM 2336 C C . ASP B 2 9 ? 5.181 7.555 -1.415 1.00 16.26 ? 77 ASP P C 1 |
| ATOM 2337 O O . ASP B 2 9 ? 5.972 6.772 -0.887 1.00 15.63 ? 77 ASP P O 1 |
| ATOM 2338 C CB . ASP B 2 9 ? 4.405 8.714 0.652 1.00 16.68 ? 77 ASP P CB 1 |
| ATOM 2339 C CG . ASP B 2 9 ? 5.079 10.032 0.398 1.00 17.72 ? 77 ASP P CG 1 |
| ATOM 2340 O OD1 . ASP B 2 9 ? 6.141 10.053 -0.259 1.00 16.97 ? 77 ASP P OD1 1 |
| ATOM 2341 O OD2 . ASP B 2 9 ? 4.546 11.064 0.859 1.00 20.98 ? 77 ASP P OD2 1 |
| ATOM 2342 N N . GLU B 2 10 ? 5.340 8.025 -2.654 1.00 15.11 ? 78 GLU P N 1 |
| ATOM 2343 C CA . GLU B 2 10 ? 6.407 7.521 -3.533 1.00 15.13 ? 78 GLU P CA 1 |
| ATOM 2344 C C . GLU B 2 10 ? 7.796 7.904 -3.053 1.00 14.57 ? 78 GLU P C 1 |
| ATOM 2345 O O . GLU B 2 10 ? 8.783 7.265 -3.429 1.00 15.07 ? 78 GLU P O 1 |
| ATOM 2346 C CB . GLU B 2 10 ? 6.201 8.017 -4.963 1.00 15.75 ? 78 GLU P CB 1 |
| ATOM 2347 N N . GLU B 2 11 ? 7.874 8.948 -2.235 1.00 14.38 ? 79 GLU P N 1 |
| ATOM 2348 C CA . GLU B 2 11 ? 9.165 9.471 -1.783 1.00 13.82 ? 79 GLU P CA 1 |
| ATOM 2349 C C . GLU B 2 11 ? 9.618 8.905 -0.437 1.00 13.22 ? 79 GLU P C 1 |
| ATOM 2350 O O . GLU B 2 11 ? 10.813 8.709 -0.209 1.00 13.81 ? 79 GLU P O 1 |
| ATOM 2351 C CB . GLU B 2 11 ? 9.117 10.997 -1.675 1.00 14.65 ? 79 GLU P CB 1 |
| ATOM 2352 C CG . GLU B 2 11 ? 8.929 11.681 -3.006 1.00 15.68 ? 79 GLU P CG 1 |
| ATOM 2353 C CD . GLU B 2 11 ? 8.909 13.198 -2.914 1.00 16.52 ? 79 GLU P CD 1 |
| ATOM 2354 O OE1 . GLU B 2 11 ? 9.552 13.756 -2.001 1.00 18.22 ? 79 GLU P OE1 1 |
| ATOM 2355 O OE2 . GLU B 2 11 ? 8.260 13.827 -3.773 1.00 19.56 ? 79 GLU P OE2 1 |
| ATOM 2356 N N . THR B 2 12 ? 8.664 8.667 0.463 1.00 12.00 ? 80 THR P N 1 |
| ATOM 2357 C CA . THR B 2 12 ? 9.012 8.265 1.827 1.00 12.07 ? 80 THR P CA 1 |
| ATOM 2358 C C . THR B 2 12 ? 8.662 6.809 2.092 1.00 11.64 ? 80 THR P C 1 |
| ATOM 2359 O O . THR B 2 12 ? 9.143 6.216 3.064 1.00 12.33 ? 80 THR P O 1 |
| ATOM 2360 C CB . THR B 2 12 ? 8.276 9.111 2.892 1.00 12.74 ? 80 THR P CB 1 |
| ATOM 2361 O OG1 . THR B 2 12 ? 6.878 8.820 2.856 1.00 12.67 ? 80 THR P OG1 1 |
| ATOM 2362 C CG2 . THR B 2 12 ? 8.499 10.601 2.641 1.00 12.44 ? 80 THR P CG2 1 |
| ATOM 2363 N N . GLY B 2 13 ? 7.767 6.267 1.265 1.00 11.98 ? 81 GLY P N 1 |
| ATOM 2364 C CA . GLY B 2 13 ? 7.289 4.908 1.463 1.00 12.18 ? 81 GLY P CA 1 |
| ATOM 2365 C C . GLY B 2 13 ? 6.206 4.780 2.518 1.00 13.50 ? 81 GLY P C 1 |
| ATOM 2366 O O . GLY B 2 13 ? 5.691 3.682 2.757 1.00 13.67 ? 81 GLY P O 1 |
| ATOM 2367 N N . GLU B 2 14 ? 5.830 5.888 3.159 1.00 13.55 ? 82 GLU P N 1 |
| ATOM 2368 C CA . GLU B 2 14 ? 4.736 5.837 4.144 1.00 14.86 ? 82 GLU P CA 1 |
| ATOM 2369 C C . GLU B 2 14 ? 3.385 5.617 3.474 1.00 16.06 ? 82 GLU P C 1 |
| ATOM 2370 O O . GLU B 2 14 ? 3.155 6.078 2.353 1.00 16.15 ? 82 GLU P O 1 |
| ATOM 2371 C CB . GLU B 2 14 ? 4.683 7.128 4.966 1.00 14.44 ? 82 GLU P CB 1 |
| ATOM 2372 C CG . GLU B 2 14 ? 5.963 7.380 5.780 1.00 13.57 ? 82 GLU P CG 1 |
| ATOM 2373 C CD . GLU B 2 14 ? 5.795 8.400 6.914 1.00 14.93 ? 82 GLU P CD 1 |
| ATOM 2374 O OE1 . GLU B 2 14 ? 4.640 8.743 7.256 1.00 14.85 ? 82 GLU P OE1 1 |
| ATOM 2375 O OE2 . GLU B 2 14 ? 6.815 8.864 7.476 1.00 14.47 ? 82 GLU P OE2 1 |
| ATOM 2376 N N . PHE B 2 15 ? 2.488 4.919 4.175 1.00 19.17 ? 83 PHE P N 1 |
| ATOM 2377 C CA . PHE B 2 15 ? 1.114 4.776 3.701 1.00 21.34 ? 83 PHE P CA 1 |
| ATOM 2378 C C . PHE B 2 15 ? 0.240 5.663 4.543 1.00 23.08 ? 83 PHE P C 1 |
| ATOM 2379 O O . PHE B 2 15 ? 0.388 5.699 5.771 1.00 23.82 ? 83 PHE P O 1 |
| ATOM 2380 C CB . PHE B 2 15 ? 0.619 3.319 3.796 1.00 22.14 ? 83 PHE P CB 1 |
| ATOM 2381 C CG . PHE B 2 15 ? 0.994 2.474 2.606 1.00 23.56 ? 83 PHE P CG 1 |
| ATOM 2382 C CD1 . PHE B 2 15 ? 2.142 1.691 2.628 1.00 25.41 ? 83 PHE P CD1 1 |
| ATOM 2383 C CD2 . PHE B 2 15 ? 0.203 2.471 1.456 1.00 24.64 ? 83 PHE P CD2 1 |
| ATOM 2384 C CE1 . PHE B 2 15 ? 2.498 0.905 1.522 1.00 26.08 ? 83 PHE P CE1 1 |
| ATOM 2385 C CE2 . PHE B 2 15 ? 0.548 1.692 0.347 1.00 25.01 ? 83 PHE P CE2 1 |
| ATOM 2386 C CZ . PHE B 2 15 ? 1.699 0.911 0.379 1.00 25.24 ? 83 PHE P CZ 1 |
| ATOM 2387 N N . LEU B 2 16 ? -0.675 6.367 3.874 1.00 24.58 ? 84 LEU P N 1 |
| ATOM 2388 C CA . LEU B 2 16 ? -1.570 7.322 4.514 1.00 26.56 ? 84 LEU P CA 1 |
| ATOM 2389 C C . LEU B 2 16 ? -2.951 7.281 3.857 1.00 27.17 ? 84 LEU P C 1 |
| ATOM 2390 O O . LEU B 2 16 ? -3.073 7.123 2.637 1.00 27.78 ? 84 LEU P O 1 |
| ATOM 2391 C CB . LEU B 2 16 ? -0.974 8.733 4.412 1.00 26.66 ? 84 LEU P CB 1 |
| ATOM 2392 C CG . LEU B 2 16 ? -1.722 9.901 5.061 1.00 28.87 ? 84 LEU P CG 1 |
| ATOM 2393 C CD1 . LEU B 2 16 ? -1.472 9.961 6.555 1.00 30.03 ? 84 LEU P CD1 1 |
| ATOM 2394 C CD2 . LEU B 2 16 ? -1.301 11.202 4.413 1.00 29.51 ? 84 LEU P CD2 1 |
| ATOM 2395 O OXT . LEU B 2 16 ? -3.986 7.409 4.531 1.00 28.46 ? 84 LEU P OXT 1 |
| HETATM 2396 O O . HOH C 3 . ? 7.504 32.556 7.171 1.00 16.55 ? 610 HOH X O 1 |
| HETATM 2397 O O . HOH C 3 . ? 15.111 35.990 -6.328 1.00 13.33 ? 611 HOH X O 1 |
| HETATM 2398 O O . HOH C 3 . ? 20.391 1.873 13.995 1.00 20.61 ? 612 HOH X O 1 |
| HETATM 2399 O O . HOH C 3 . ? 15.527 4.211 21.497 1.00 17.03 ? 613 HOH X O 1 |
| HETATM 2400 O O . HOH C 3 . ? 26.996 31.263 1.541 1.00 24.57 ? 614 HOH X O 1 |
| HETATM 2401 O O . HOH C 3 . ? 26.615 11.689 -8.587 1.00 13.96 ? 615 HOH X O 1 |
| HETATM 2402 O O . HOH C 3 . ? 16.908 27.696 -8.333 1.00 15.70 ? 616 HOH X O 1 |
| HETATM 2403 O O . HOH C 3 . ? 16.277 6.395 13.965 1.00 21.08 ? 617 HOH X O 1 |
| HETATM 2404 O O . HOH C 3 . ? 3.611 5.338 15.326 1.00 19.74 ? 618 HOH X O 1 |
| HETATM 2405 O O . HOH C 3 . ? 18.667 16.938 4.471 1.00 14.31 ? 619 HOH X O 1 |
| HETATM 2406 O O . HOH C 3 . ? 24.513 23.457 8.015 1.00 18.05 ? 620 HOH X O 1 |
| HETATM 2407 O O . HOH C 3 . ? 18.583 1.507 -2.864 1.00 17.45 ? 621 HOH X O 1 |
| HETATM 2408 O O . HOH C 3 . ? 23.175 38.212 8.163 1.00 23.29 ? 622 HOH X O 1 |
| HETATM 2409 O O . HOH C 3 . ? 12.831 0.179 11.447 1.00 20.45 ? 623 HOH X O 1 |
| HETATM 2410 O O . HOH C 3 . ? 21.038 24.411 23.011 1.00 22.40 ? 624 HOH X O 1 |
| HETATM 2411 O O . HOH C 3 . ? 20.788 8.838 -9.846 1.00 21.86 ? 625 HOH X O 1 |
| HETATM 2412 O O . HOH C 3 . ? 16.051 8.089 6.756 1.00 18.36 ? 626 HOH X O 1 |
| HETATM 2413 O O . HOH C 3 . ? 15.339 17.763 -1.242 1.00 16.00 ? 627 HOH X O 1 |
| HETATM 2414 O O . HOH C 3 . ? -4.124 21.513 7.102 1.00 18.44 ? 628 HOH X O 1 |
| HETATM 2415 O O . HOH C 3 . ? 12.126 37.498 0.783 1.00 15.91 ? 629 HOH X O 1 |
| HETATM 2416 O O . HOH C 3 . ? -0.329 24.085 -0.001 1.00 18.64 ? 630 HOH X O 1 |
| HETATM 2417 O O . HOH C 3 . ? 15.819 43.699 -1.903 1.00 19.50 ? 631 HOH X O 1 |
| HETATM 2418 O O . HOH C 3 . ? 7.279 20.848 21.598 1.00 17.43 ? 632 HOH X O 1 |
| HETATM 2419 O O . HOH C 3 . ? 10.819 13.201 22.708 1.00 20.98 ? 633 HOH X O 1 |
| HETATM 2420 O O . HOH C 3 . ? 9.017 13.055 20.347 1.00 20.36 ? 634 HOH X O 1 |
| HETATM 2421 O O . HOH C 3 . ? 17.858 15.292 10.221 1.00 14.28 ? 635 HOH X O 1 |
| HETATM 2422 O O . HOH C 3 . ? 17.228 19.181 7.912 1.00 13.55 ? 636 HOH X O 1 |
| HETATM 2423 O O . HOH C 3 . ? 2.348 13.886 16.202 1.00 21.07 ? 637 HOH X O 1 |
| HETATM 2424 O O . HOH C 3 . ? 23.693 35.559 9.253 1.00 33.22 ? 638 HOH X O 1 |
| HETATM 2425 O O . HOH C 3 . ? 21.511 43.405 -3.158 1.00 22.24 ? 639 HOH X O 1 |
| HETATM 2426 O O . HOH C 3 . ? 6.844 11.755 6.820 1.00 17.61 ? 640 HOH X O 1 |
| HETATM 2427 O O . HOH C 3 . ? 11.018 27.334 -7.165 1.00 25.36 ? 641 HOH X O 1 |
| HETATM 2428 O O . HOH C 3 . ? 7.303 30.312 21.029 1.00 23.42 ? 642 HOH X O 1 |
| HETATM 2429 O O . HOH C 3 . ? 23.629 9.555 25.979 1.00 21.32 ? 643 HOH X O 1 |
| HETATM 2430 O O . HOH C 3 . ? 15.096 12.228 6.886 1.00 19.10 ? 644 HOH X O 1 |
| HETATM 2431 O O . HOH C 3 . ? 7.302 18.365 22.780 1.00 22.90 ? 645 HOH X O 1 |
| HETATM 2432 O O . HOH C 3 . ? 25.208 24.701 -12.195 1.00 18.04 ? 646 HOH X O 1 |
| HETATM 2433 O O . HOH C 3 . ? 22.256 19.609 6.954 1.00 19.88 ? 647 HOH X O 1 |
| HETATM 2434 O O . HOH C 3 . ? 25.602 28.278 15.599 1.00 26.90 ? 648 HOH X O 1 |
| HETATM 2435 O O . HOH C 3 . ? 5.069 13.160 16.439 1.00 18.37 ? 649 HOH X O 1 |
| HETATM 2436 O O . HOH C 3 . ? 22.823 23.698 10.206 1.00 20.34 ? 650 HOH X O 1 |
| HETATM 2437 O O . HOH C 3 . ? 5.270 27.599 -4.413 1.00 21.45 ? 651 HOH X O 1 |
| HETATM 2438 O O . HOH C 3 . ? 12.152 23.623 -9.671 1.00 22.38 ? 652 HOH X O 1 |
| HETATM 2439 O O . HOH C 3 . ? 23.600 11.805 33.846 1.00 19.93 ? 653 HOH X O 1 |
| HETATM 2440 O O . HOH C 3 . ? 2.558 18.510 17.642 1.00 23.62 ? 654 HOH X O 1 |
| HETATM 2441 O O . HOH C 3 . ? 33.579 9.093 17.603 1.00 33.26 ? 655 HOH X O 1 |
| HETATM 2442 O O . HOH C 3 . ? 9.726 36.263 1.342 1.00 19.87 ? 656 HOH X O 1 |
| HETATM 2443 O O . HOH C 3 . ? 22.657 16.726 10.981 1.00 25.41 ? 657 HOH X O 1 |
| HETATM 2444 O O . HOH C 3 . ? 30.864 -0.444 0.459 1.00 33.05 ? 658 HOH X O 1 |
| HETATM 2445 O O . HOH C 3 . ? 32.519 5.490 -4.697 1.00 22.46 ? 659 HOH X O 1 |
| HETATM 2446 O O . HOH C 3 . ? 33.999 10.006 10.456 1.00 23.21 ? 660 HOH X O 1 |
| HETATM 2447 O O . HOH C 3 . ? 29.067 2.654 -0.972 1.00 23.00 ? 661 HOH X O 1 |
| HETATM 2448 O O . HOH C 3 . ? 27.751 3.998 19.701 1.00 27.25 ? 662 HOH X O 1 |
| HETATM 2449 O O . HOH C 3 . ? 27.214 -2.407 17.737 1.00 32.84 ? 663 HOH X O 1 |
| HETATM 2450 O O . HOH C 3 . ? 30.444 23.175 -8.031 1.00 20.42 ? 664 HOH X O 1 |
| HETATM 2451 O O . HOH C 3 . ? 19.277 -3.948 9.712 1.00 22.27 ? 665 HOH X O 1 |
| HETATM 2452 O O . HOH C 3 . ? 7.344 7.008 21.930 1.00 28.27 ? 666 HOH X O 1 |
| HETATM 2453 O O . HOH C 3 . ? 15.875 16.143 -13.230 1.00 24.04 ? 667 HOH X O 1 |
| HETATM 2454 O O . HOH C 3 . ? 21.797 29.191 21.298 1.00 25.90 ? 668 HOH X O 1 |
| HETATM 2455 O O . HOH C 3 . ? 18.780 19.398 5.618 1.00 14.36 ? 669 HOH X O 1 |
| HETATM 2456 O O . HOH C 3 . ? 15.631 13.431 3.114 1.00 20.74 ? 670 HOH X O 1 |
| HETATM 2457 O O . HOH C 3 . ? 15.362 17.294 6.937 1.00 15.91 ? 671 HOH X O 1 |
| HETATM 2458 O O . HOH C 3 . ? 12.372 16.008 5.959 1.00 19.55 ? 672 HOH X O 1 |
| HETATM 2459 O O . HOH C 3 . ? 12.821 13.687 7.358 1.00 19.39 ? 673 HOH X O 1 |
| HETATM 2460 O O . HOH C 3 . ? 3.380 28.579 4.618 1.00 26.07 ? 674 HOH X O 1 |
| HETATM 2461 O O . HOH C 3 . ? 0.941 11.855 18.064 1.00 29.47 ? 675 HOH X O 1 |
| HETATM 2462 O O . HOH C 3 . ? -2.056 16.272 11.145 1.00 23.56 ? 676 HOH X O 1 |
| HETATM 2463 O O . HOH C 3 . ? 7.257 15.117 20.486 1.00 20.93 ? 677 HOH X O 1 |
| HETATM 2464 O O . HOH C 3 . ? 29.057 18.103 -13.062 1.00 19.79 ? 678 HOH X O 1 |
| HETATM 2465 O O . HOH C 3 . ? 24.811 20.863 7.148 1.00 20.07 ? 679 HOH X O 1 |
| HETATM 2466 O O . HOH C 3 . ? 2.919 29.807 10.771 1.00 26.30 ? 680 HOH X O 1 |
| HETATM 2467 O O . HOH C 3 . ? 23.187 20.464 13.530 1.00 24.41 ? 681 HOH X O 1 |
| HETATM 2468 O O . HOH C 3 . ? 18.842 14.991 6.500 1.00 17.99 ? 682 HOH X O 1 |
| HETATM 2469 O O . HOH C 3 . ? 13.727 37.558 -3.804 1.00 21.68 ? 683 HOH X O 1 |
| HETATM 2470 O O . HOH C 3 . ? 7.491 16.903 -10.631 1.00 23.32 ? 684 HOH X O 1 |
| HETATM 2471 O O . HOH C 3 . ? 5.723 15.138 18.204 1.00 20.20 ? 685 HOH X O 1 |
| HETATM 2472 O O . HOH C 3 . ? 20.911 2.037 -6.305 1.00 25.76 ? 686 HOH X O 1 |
| HETATM 2473 O O . HOH C 3 . ? 10.328 15.104 24.615 1.00 23.31 ? 687 HOH X O 1 |
| HETATM 2474 O O . HOH C 3 . ? 19.457 28.105 -12.616 1.00 23.00 ? 688 HOH X O 1 |
| HETATM 2475 O O . HOH C 3 . ? 25.265 23.559 15.655 1.00 28.01 ? 689 HOH X O 1 |
| HETATM 2476 O O . HOH C 3 . ? 15.824 17.275 4.169 1.00 20.67 ? 690 HOH X O 1 |
| HETATM 2477 O O . HOH C 3 . ? 33.956 6.016 2.603 1.00 23.77 ? 691 HOH X O 1 |
| HETATM 2478 O O . HOH C 3 . ? 25.483 9.199 23.996 1.00 24.18 ? 692 HOH X O 1 |
| HETATM 2479 O O . HOH C 3 . ? 24.684 17.759 13.172 1.00 27.69 ? 693 HOH X O 1 |
| HETATM 2480 O O . HOH C 3 . ? 3.116 20.405 19.492 1.00 27.25 ? 694 HOH X O 1 |
| HETATM 2481 O O . HOH C 3 . ? 33.015 20.559 6.977 1.00 31.52 ? 695 HOH X O 1 |
| HETATM 2482 O O . HOH C 3 . ? 19.770 31.085 22.335 1.00 36.31 ? 696 HOH X O 1 |
| HETATM 2483 O O . HOH C 3 . ? 35.409 15.324 -3.427 1.00 25.48 ? 697 HOH X O 1 |
| HETATM 2484 O O . HOH C 3 . ? -1.338 24.888 8.831 1.00 29.07 ? 698 HOH X O 1 |
| HETATM 2485 O O . HOH C 3 . ? 19.083 18.329 9.746 1.00 19.70 ? 699 HOH X O 1 |
| HETATM 2486 O O . HOH C 3 . ? 13.565 10.711 28.267 1.00 31.72 ? 700 HOH X O 1 |
| HETATM 2487 O O . HOH C 3 . ? 33.377 17.764 10.543 1.00 25.73 ? 701 HOH X O 1 |
| HETATM 2488 O O . HOH C 3 . ? 4.292 13.091 3.769 1.00 25.90 ? 702 HOH X O 1 |
| HETATM 2489 O O . HOH C 3 . ? 9.704 2.642 17.962 1.00 29.40 ? 703 HOH X O 1 |
| HETATM 2490 O O . HOH C 3 . ? 16.541 35.587 11.445 1.00 31.76 ? 704 HOH X O 1 |
| HETATM 2491 O O . HOH C 3 . ? 17.422 23.668 25.195 1.00 30.90 ? 705 HOH X O 1 |
| HETATM 2492 O O . HOH C 3 . ? 26.597 -1.870 -0.011 1.00 25.45 ? 706 HOH X O 1 |
| HETATM 2493 O O . HOH C 3 . ? 32.501 24.948 -9.078 1.00 20.43 ? 707 HOH X O 1 |
| HETATM 2494 O O . HOH C 3 . ? 32.591 22.032 -6.625 1.00 25.42 ? 708 HOH X O 1 |
| HETATM 2495 O O . HOH C 3 . ? 20.456 0.047 -4.288 1.00 25.17 ? 709 HOH X O 1 |
| HETATM 2496 O O . HOH C 3 . ? 3.434 31.928 4.489 1.00 29.22 ? 710 HOH X O 1 |
| HETATM 2497 O O . HOH C 3 . ? 20.309 33.759 12.801 1.00 35.00 ? 711 HOH X O 1 |
| HETATM 2498 O O . HOH C 3 . ? 32.661 3.904 10.593 1.00 28.60 ? 712 HOH X O 1 |
| HETATM 2499 O O . HOH C 3 . ? 17.062 -1.998 -3.226 1.00 26.91 ? 713 HOH X O 1 |
| HETATM 2500 O O . HOH C 3 . ? 2.786 28.674 8.213 1.00 25.71 ? 714 HOH X O 1 |
| HETATM 2501 O O . HOH C 3 . ? 22.730 23.737 -12.543 1.00 28.45 ? 715 HOH X O 1 |
| HETATM 2502 O O . HOH C 3 . ? 13.299 4.572 26.441 1.00 31.78 ? 716 HOH X O 1 |
| HETATM 2503 O O . HOH C 3 . ? 28.266 26.121 7.800 1.00 26.97 ? 717 HOH X O 1 |
| HETATM 2504 O O . HOH C 3 . ? 6.551 30.945 15.840 1.00 25.02 ? 718 HOH X O 1 |
| HETATM 2505 O O . HOH C 3 . ? 16.331 14.886 8.003 1.00 18.82 ? 719 HOH X O 1 |
| HETATM 2506 O O . HOH C 3 . ? 28.874 -1.560 12.342 1.00 28.02 ? 720 HOH X O 1 |
| HETATM 2507 O O . HOH C 3 . ? 11.924 39.643 2.598 1.00 24.92 ? 721 HOH X O 1 |
| HETATM 2508 O O . HOH C 3 . ? 11.070 -1.247 12.818 1.00 27.36 ? 722 HOH X O 1 |
| HETATM 2509 O O . HOH C 3 . ? 5.519 28.213 20.975 1.00 29.79 ? 723 HOH X O 1 |
| HETATM 2510 O O . HOH C 3 . ? 26.481 4.054 -7.788 1.00 22.93 ? 724 HOH X O 1 |
| HETATM 2511 O O . HOH C 3 . ? 11.886 13.595 2.697 1.00 26.26 ? 725 HOH X O 1 |
| HETATM 2512 O O . HOH C 3 . ? 22.444 -0.655 23.032 1.00 31.18 ? 726 HOH X O 1 |
| HETATM 2513 O O . HOH C 3 . ? 16.813 16.885 27.975 1.00 25.49 ? 727 HOH X O 1 |
| HETATM 2514 O O . HOH C 3 . ? 20.780 20.873 8.947 1.00 23.16 ? 728 HOH X O 1 |
| HETATM 2515 O O . HOH C 3 . ? 26.211 -7.214 1.688 1.00 30.99 ? 729 HOH X O 1 |
| HETATM 2516 O O . HOH C 3 . ? 1.456 6.431 18.865 1.00 28.51 ? 730 HOH X O 1 |
| HETATM 2517 O O . HOH C 3 . ? 14.110 25.667 -11.554 1.00 30.11 ? 731 HOH X O 1 |
| HETATM 2518 O O . HOH C 3 . ? 6.150 35.093 15.103 1.00 31.86 ? 732 HOH X O 1 |
| HETATM 2519 O O . HOH C 3 . ? 25.511 17.940 26.728 1.00 30.77 ? 733 HOH X O 1 |
| HETATM 2520 O O . HOH C 3 . ? 28.560 19.519 19.246 1.00 29.69 ? 734 HOH X O 1 |
| HETATM 2521 O O . HOH C 3 . ? 30.426 5.803 -6.509 1.00 30.36 ? 735 HOH X O 1 |
| HETATM 2522 O O . HOH C 3 . ? 6.719 36.276 8.418 1.00 35.78 ? 736 HOH X O 1 |
| HETATM 2523 O O . HOH C 3 . ? 26.209 25.331 19.228 1.00 36.30 ? 737 HOH X O 1 |
| HETATM 2524 O O . HOH C 3 . ? 22.394 35.549 11.818 1.00 34.85 ? 738 HOH X O 1 |
| HETATM 2525 O O . HOH C 3 . ? 23.306 17.573 8.330 1.00 27.68 ? 739 HOH X O 1 |
| HETATM 2526 O O . HOH C 3 . ? 8.273 30.453 -6.842 1.00 40.31 ? 740 HOH X O 1 |
| HETATM 2527 O O . HOH C 3 . ? 26.503 30.360 12.721 1.00 33.00 ? 741 HOH X O 1 |
| HETATM 2528 O O . HOH C 3 . ? 30.545 11.313 22.640 1.00 35.94 ? 742 HOH X O 1 |
| HETATM 2529 O O . HOH C 3 . ? 1.446 16.411 5.770 1.00 31.05 ? 743 HOH X O 1 |
| HETATM 2530 O O . HOH C 3 . ? 29.964 11.643 -10.997 1.00 28.52 ? 744 HOH X O 1 |
| HETATM 2531 O O . HOH C 3 . ? 15.692 2.450 25.109 1.00 33.99 ? 745 HOH X O 1 |
| HETATM 2532 O O . HOH C 3 . ? 3.274 1.212 6.224 1.00 26.39 ? 746 HOH X O 1 |
| HETATM 2533 O O . HOH C 3 . ? 34.029 20.307 -8.111 1.00 38.39 ? 747 HOH X O 1 |
| HETATM 2534 O O . HOH C 3 . ? 6.359 26.526 -6.837 1.00 28.48 ? 748 HOH X O 1 |
| HETATM 2535 O O . HOH C 3 . ? 23.052 43.978 5.254 1.00 35.29 ? 749 HOH X O 1 |
| HETATM 2536 O O . HOH C 3 . ? 20.156 16.124 8.596 1.00 20.38 ? 750 HOH X O 1 |
| HETATM 2537 O O . HOH C 3 . ? 18.069 35.723 -7.221 1.00 23.36 ? 751 HOH X O 1 |
| HETATM 2538 O O . HOH C 3 . ? 10.271 1.897 20.713 1.00 35.87 ? 752 HOH X O 1 |
| HETATM 2539 O O . HOH C 3 . ? 25.645 26.245 11.497 1.00 29.01 ? 753 HOH X O 1 |
| HETATM 2540 O O . HOH C 3 . ? 28.586 33.445 1.108 1.00 27.92 ? 754 HOH X O 1 |
| HETATM 2541 O O . HOH C 3 . ? 15.731 -1.754 15.512 1.00 38.86 ? 755 HOH X O 1 |
| HETATM 2542 O O . HOH C 3 . ? 23.633 33.461 -6.729 1.00 36.83 ? 756 HOH X O 1 |
| HETATM 2543 O O . HOH C 3 . ? 28.195 21.373 -13.534 1.00 30.56 ? 757 HOH X O 1 |
| HETATM 2544 O O . HOH C 3 . ? 18.059 16.444 30.564 1.00 28.73 ? 758 HOH X O 1 |
| HETATM 2545 O O . HOH C 3 . ? 24.285 32.414 -2.181 1.00 29.21 ? 759 HOH X O 1 |
| HETATM 2546 O O . HOH C 3 . ? 27.327 17.547 11.587 1.00 33.13 ? 760 HOH X O 1 |
| HETATM 2547 O O . HOH C 3 . ? 24.709 18.886 -15.831 1.00 24.86 ? 761 HOH X O 1 |
| HETATM 2548 O O . HOH C 3 . ? 33.318 5.692 8.676 1.00 33.89 ? 762 HOH X O 1 |
| HETATM 2549 O O . HOH C 3 . ? 27.206 21.926 19.733 1.00 29.79 ? 763 HOH X O 1 |
| HETATM 2550 O O . HOH C 3 . ? -3.059 18.356 12.526 1.00 27.40 ? 764 HOH X O 1 |
| HETATM 2551 O O . HOH C 3 . ? 23.762 31.149 -7.737 1.00 26.49 ? 765 HOH X O 1 |
| HETATM 2552 O O . HOH C 3 . ? 35.767 5.565 0.831 1.00 32.05 ? 766 HOH X O 1 |
| HETATM 2553 O O . HOH C 3 . ? 0.780 14.588 7.065 1.00 27.78 ? 767 HOH X O 1 |
| HETATM 2554 O O . HOH C 3 . ? 10.503 4.676 -6.995 1.00 30.75 ? 768 HOH X O 1 |
| HETATM 2555 O O . HOH C 3 . ? 5.940 14.938 -10.014 1.00 37.85 ? 769 HOH X O 1 |
| HETATM 2556 O O . HOH C 3 . ? 1.373 27.398 5.604 1.00 28.55 ? 770 HOH X O 1 |
| HETATM 2557 O O . HOH C 3 . ? 9.528 15.641 -12.071 1.00 30.05 ? 771 HOH X O 1 |
| HETATM 2558 O O . HOH C 3 . ? 9.513 -4.460 -2.915 1.00 32.15 ? 772 HOH X O 1 |
| HETATM 2559 O O . HOH C 3 . ? 30.864 14.152 22.163 1.00 37.38 ? 773 HOH X O 1 |
| HETATM 2560 O O . HOH C 3 . ? 6.874 33.871 -0.475 1.00 37.49 ? 774 HOH X O 1 |
| HETATM 2561 O O . HOH C 3 . ? 7.558 30.244 23.903 1.00 29.36 ? 775 HOH X O 1 |
| HETATM 2562 O O . HOH C 3 . ? 30.476 2.838 -3.487 1.00 27.40 ? 776 HOH X O 1 |
| HETATM 2563 O O . HOH C 3 . ? 15.605 25.795 25.216 1.00 29.02 ? 777 HOH X O 1 |
| HETATM 2564 O O . HOH C 3 . ? -0.927 10.377 15.629 1.00 34.46 ? 778 HOH X O 1 |
| HETATM 2565 O O . HOH C 3 . ? 1.817 -0.413 8.202 1.00 34.63 ? 779 HOH X O 1 |
| HETATM 2566 O O . HOH C 3 . ? 19.790 18.806 30.287 1.00 26.18 ? 780 HOH X O 1 |
| HETATM 2567 O O . HOH C 3 . ? 24.976 32.080 -4.649 1.00 37.42 ? 781 HOH X O 1 |
| HETATM 2568 O O . HOH C 3 . ? 14.544 9.112 -13.531 1.00 33.21 ? 782 HOH X O 1 |
| HETATM 2569 O O . HOH C 3 . ? 0.218 20.754 16.488 1.00 31.41 ? 783 HOH X O 1 |
| HETATM 2570 O O . HOH C 3 . ? 16.022 -5.717 12.390 1.00 38.70 ? 784 HOH X O 1 |
| HETATM 2571 O O . HOH C 3 . ? 24.278 8.188 -10.820 1.00 33.58 ? 785 HOH X O 1 |
| HETATM 2572 O O . HOH C 3 . ? 19.926 44.490 5.666 1.00 30.05 ? 786 HOH X O 1 |
| HETATM 2573 O O . HOH C 3 . ? 19.244 23.022 -14.108 1.00 31.93 ? 787 HOH X O 1 |
| HETATM 2574 O O . HOH C 3 . ? 31.735 30.961 -12.186 1.00 39.31 ? 788 HOH X O 1 |
| HETATM 2575 O O . HOH C 3 . ? 39.276 14.592 -3.663 1.00 36.71 ? 789 HOH X O 1 |
| HETATM 2576 O O . HOH C 3 . ? 18.137 4.257 27.585 1.00 33.99 ? 790 HOH X O 1 |
| HETATM 2577 O O . HOH C 3 . ? 6.218 22.106 25.238 1.00 33.69 ? 791 HOH X O 1 |
| HETATM 2578 O O . HOH C 3 . ? -4.114 14.383 10.714 1.00 34.35 ? 792 HOH X O 1 |
| HETATM 2579 O O . HOH C 3 . ? 37.683 15.103 4.960 1.00 34.70 ? 793 HOH X O 1 |
| HETATM 2580 O O . HOH C 3 . ? 24.654 36.381 6.957 1.00 32.12 ? 794 HOH X O 1 |
| HETATM 2581 O O . HOH C 3 . ? 19.299 11.266 33.643 1.00 22.57 ? 795 HOH X O 1 |
| HETATM 2582 O O . HOH C 3 . ? 6.860 3.532 -4.143 1.00 33.41 ? 796 HOH X O 1 |
| HETATM 2583 O O . HOH C 3 . ? 38.620 12.535 5.000 1.00 34.16 ? 797 HOH X O 1 |
| HETATM 2584 O O . HOH C 3 . ? 9.438 38.689 8.805 1.00 33.52 ? 798 HOH X O 1 |
| HETATM 2585 O O . HOH C 3 . ? 25.985 17.917 9.296 1.00 31.86 ? 799 HOH X O 1 |
| HETATM 2586 O O . HOH C 3 . ? 28.262 35.209 4.007 1.00 44.84 ? 800 HOH X O 1 |
| HETATM 2587 O O . HOH C 3 . ? 17.880 31.110 -10.487 1.00 37.81 ? 801 HOH X O 1 |
| HETATM 2588 O O . HOH C 3 . ? 7.224 -0.522 15.245 1.00 35.38 ? 802 HOH X O 1 |
| HETATM 2589 O O . HOH C 3 . ? -1.003 18.507 14.770 1.00 31.68 ? 803 HOH X O 1 |
| HETATM 2590 O O . HOH C 3 . ? 43.622 15.396 2.127 1.00 36.69 ? 804 HOH X O 1 |
| HETATM 2591 O O . HOH C 3 . ? 25.922 22.675 -14.136 1.00 33.28 ? 805 HOH X O 1 |
| HETATM 2592 O O . HOH C 3 . ? 8.729 4.497 24.100 1.00 39.06 ? 806 HOH X O 1 |
| HETATM 2593 O O . HOH C 3 . ? 12.035 8.245 26.757 1.00 37.20 ? 807 HOH X O 1 |
| HETATM 2594 O O . HOH C 3 . ? 12.820 42.523 8.281 1.00 36.41 ? 808 HOH X O 1 |
| HETATM 2595 O O . HOH C 3 . ? 41.038 9.900 3.186 1.00 31.87 ? 809 HOH X O 1 |
| HETATM 2596 O O . HOH C 3 . ? 15.257 8.937 29.921 1.00 30.13 ? 810 HOH X O 1 |
| HETATM 2597 O O . HOH C 3 . ? 32.183 22.015 -12.433 1.00 35.21 ? 811 HOH X O 1 |
| HETATM 2598 O O . HOH C 3 . ? 13.482 22.023 27.606 1.00 37.33 ? 812 HOH X O 1 |
| HETATM 2599 O O . HOH C 3 . ? 7.303 33.741 -4.403 1.00 35.28 ? 813 HOH X O 1 |
| HETATM 2600 O O . HOH C 3 . ? 25.094 1.625 -7.567 1.00 31.37 ? 814 HOH X O 1 |
| HETATM 2601 O O . HOH C 3 . ? 27.179 19.939 7.895 1.00 34.14 ? 815 HOH X O 1 |
| HETATM 2602 O O . HOH C 3 . ? 9.804 21.106 -11.476 1.00 32.66 ? 816 HOH X O 1 |
| HETATM 2603 O O . HOH C 3 . ? 40.016 7.922 -4.959 1.00 34.15 ? 817 HOH X O 1 |
| HETATM 2604 O O . HOH C 3 . ? 23.710 -2.667 13.106 1.00 44.53 ? 818 HOH X O 1 |
| HETATM 2605 O O . HOH C 3 . ? 27.276 33.788 -4.915 1.00 34.14 ? 819 HOH X O 1 |
| HETATM 2606 O O . HOH C 3 . ? 25.624 20.609 26.270 1.00 39.58 ? 820 HOH X O 1 |
| HETATM 2607 O O . HOH C 3 . ? 21.990 22.424 -14.735 1.00 33.11 ? 821 HOH X O 1 |
| HETATM 2608 O O . HOH C 3 . ? 34.892 1.935 4.292 1.00 38.19 ? 822 HOH X O 1 |
| HETATM 2609 O O . HOH C 3 . ? 37.184 12.085 -8.371 1.00 36.50 ? 823 HOH X O 1 |
| HETATM 2610 O O . HOH C 3 . ? 12.908 14.012 -13.512 1.00 34.71 ? 824 HOH X O 1 |
| HETATM 2611 O O . HOH C 3 . ? -7.644 3.682 12.740 1.00 31.38 ? 825 HOH X O 1 |
| HETATM 2612 O O . HOH C 3 . ? -0.210 16.179 1.595 1.00 44.56 ? 826 HOH X O 1 |
| HETATM 2613 O O . HOH C 3 . ? 28.176 29.361 8.657 1.00 25.31 ? 827 HOH X O 1 |
| HETATM 2614 O O . HOH C 3 . ? 31.951 23.665 5.893 1.00 34.24 ? 828 HOH X O 1 |
| HETATM 2615 O O . HOH C 3 . ? 8.241 -1.097 12.672 1.00 23.44 ? 829 HOH X O 1 |
| HETATM 2616 O O . HOH C 3 . ? -0.847 28.107 3.101 1.00 29.27 ? 830 HOH X O 1 |
| HETATM 2617 O O . HOH C 3 . ? 13.072 41.990 1.373 1.00 28.31 ? 831 HOH X O 1 |
| HETATM 2618 O O . HOH C 3 . ? 0.917 23.762 -2.522 1.00 31.24 ? 832 HOH X O 1 |
| HETATM 2619 O O . HOH C 3 . ? 36.437 31.687 -6.604 1.00 30.63 ? 833 HOH X O 1 |
| HETATM 2620 O O . HOH C 3 . ? 39.314 11.206 -6.981 1.00 33.97 ? 834 HOH X O 1 |
| HETATM 2621 O O . HOH C 3 . ? 12.327 15.669 30.709 1.00 32.71 ? 835 HOH X O 1 |
| HETATM 2622 O O . HOH C 3 . ? 1.183 12.866 3.291 1.00 39.72 ? 836 HOH X O 1 |
| HETATM 2623 O O . HOH C 3 . ? -0.240 17.476 -3.235 1.00 39.38 ? 837 HOH X O 1 |
| HETATM 2624 O O . HOH C 3 . ? 43.315 10.984 -0.705 1.00 33.79 ? 838 HOH X O 1 |
| HETATM 2625 O O . HOH C 3 . ? 12.166 21.915 -12.415 1.00 42.35 ? 839 HOH X O 1 |
| HETATM 2626 O O . HOH C 3 . ? 25.525 29.770 -12.728 1.00 43.15 ? 840 HOH X O 1 |
| HETATM 2627 O O . HOH C 3 . ? 29.018 -3.271 2.328 1.00 41.64 ? 841 HOH X O 1 |
| HETATM 2628 O O . HOH C 3 . ? 38.276 6.758 2.395 1.00 40.43 ? 842 HOH X O 1 |
| HETATM 2629 O O . HOH C 3 . ? 3.434 16.066 18.855 1.00 35.92 ? 843 HOH X O 1 |
| HETATM 2630 O O . HOH C 3 . ? 10.189 20.693 29.244 1.00 48.05 ? 844 HOH X O 1 |
| HETATM 2631 O O . HOH C 3 . ? 31.458 26.527 -13.269 1.00 33.01 ? 845 HOH X O 1 |
| HETATM 2632 O O . HOH C 3 . ? 6.824 0.247 5.915 1.00 25.44 ? 846 HOH X O 1 |
| HETATM 2633 O O . HOH C 3 . ? -5.505 21.235 11.757 1.00 28.18 ? 847 HOH X O 1 |
| HETATM 2634 O O . HOH C 3 . ? 36.493 19.549 -0.275 1.00 32.59 ? 848 HOH X O 1 |
| HETATM 2635 O O . HOH C 3 . ? 6.346 14.540 24.883 1.00 43.63 ? 849 HOH X O 1 |
| HETATM 2636 O O . HOH C 3 . ? 35.332 6.519 4.975 1.00 41.93 ? 850 HOH X O 1 |
| HETATM 2637 O O . HOH C 3 . ? 21.222 12.853 -11.339 1.00 16.47 ? 851 HOH X O 1 |
| HETATM 2638 O O . HOH C 3 . ? 27.875 12.522 21.980 1.00 23.90 ? 852 HOH X O 1 |
| HETATM 2639 O O . HOH C 3 . ? 36.135 10.999 9.130 1.00 40.97 ? 853 HOH X O 1 |
| HETATM 2640 O O . HOH C 3 . ? 6.417 3.153 16.998 1.00 30.89 ? 854 HOH X O 1 |
| HETATM 2641 O O . HOH C 3 . ? 18.890 6.948 31.644 1.00 34.20 ? 855 HOH X O 1 |
| HETATM 2642 O O . HOH C 3 . ? 30.062 4.672 21.547 1.00 42.34 ? 856 HOH X O 1 |
| HETATM 2643 O O . HOH C 3 . ? 1.051 2.690 10.277 1.00 33.30 ? 857 HOH X O 1 |
| HETATM 2644 O O . HOH C 3 . ? 30.406 20.790 7.939 1.00 40.10 ? 858 HOH X O 1 |
| HETATM 2645 O O . HOH C 3 . ? 12.053 1.114 -9.317 1.00 42.44 ? 859 HOH X O 1 |
| HETATM 2646 O O . HOH C 3 . ? 11.462 12.486 5.148 1.00 21.39 ? 860 HOH X O 1 |
| HETATM 2647 O O . HOH C 3 . ? 9.399 11.197 5.949 1.00 15.70 ? 861 HOH X O 1 |
| HETATM 2648 O O . HOH C 3 . ? 14.968 28.036 -10.329 1.00 23.60 ? 862 HOH X O 1 |
| HETATM 2649 O O . HOH C 3 . ? 21.637 21.643 11.245 1.00 37.53 ? 863 HOH X O 1 |
| HETATM 2650 O O . HOH C 3 . ? 26.686 24.555 9.453 1.00 28.68 ? 864 HOH X O 1 |
| HETATM 2651 O O . HOH C 3 . ? 8.145 38.050 2.591 1.00 30.93 ? 865 HOH X O 1 |
| HETATM 2652 O O . HOH C 3 . ? 5.441 37.537 2.353 1.00 28.97 ? 866 HOH X O 1 |
| HETATM 2653 O O . HOH C 3 . ? 4.176 36.951 4.568 1.00 33.10 ? 867 HOH X O 1 |
| HETATM 2654 O O . HOH C 3 . ? 22.121 27.081 23.208 1.00 25.57 ? 868 HOH X O 1 |
| HETATM 2655 O O . HOH C 3 . ? 4.469 20.464 21.759 1.00 24.87 ? 869 HOH X O 1 |
| HETATM 2656 O O . HOH C 3 . ? 2.894 22.109 23.636 1.00 36.44 ? 870 HOH X O 1 |
| HETATM 2657 O O . HOH C 3 . ? 11.901 -3.839 12.625 1.00 34.76 ? 871 HOH X O 1 |
| HETATM 2658 O O . HOH C 3 . ? 13.586 15.417 3.485 1.00 24.07 ? 872 HOH X O 1 |
| HETATM 2659 O O . HOH C 3 . ? 2.563 4.260 17.561 1.00 28.05 ? 873 HOH X O 1 |
| HETATM 2660 O O . HOH C 3 . ? 27.853 14.472 24.006 1.00 33.07 ? 874 HOH X O 1 |
| HETATM 2661 O O . HOH C 3 . ? -2.710 22.781 14.538 1.00 42.57 ? 875 HOH X O 1 |
| HETATM 2662 O O . HOH C 3 . ? 28.997 18.609 23.934 1.00 42.21 ? 876 HOH X O 1 |
| HETATM 2663 O O . HOH C 3 . ? 19.334 24.811 26.658 1.00 42.64 ? 877 HOH X O 1 |
| HETATM 2664 O O . HOH C 3 . ? 17.345 7.390 -10.781 1.00 34.54 ? 878 HOH X O 1 |
| HETATM 2665 O O . HOH C 3 . ? -1.665 5.516 8.478 1.00 42.97 ? 879 HOH X O 1 |
| HETATM 2666 O O . HOH C 3 . ? 25.763 10.496 35.253 1.00 22.43 ? 880 HOH X O 1 |
| HETATM 2667 O O . HOH C 3 . ? 3.139 32.045 9.075 1.00 28.36 ? 881 HOH X O 1 |
| HETATM 2668 O O . HOH C 3 . ? 2.070 30.758 6.868 1.00 33.62 ? 882 HOH X O 1 |
| HETATM 2669 O O . HOH C 3 . ? 35.174 0.574 12.322 1.00 54.32 ? 883 HOH X O 1 |
| HETATM 2670 O O . HOH C 3 . ? 1.668 -2.883 8.863 1.00 38.41 ? 884 HOH X O 1 |
| HETATM 2671 O O . HOH C 3 . ? 5.428 29.142 18.148 1.00 36.79 ? 885 HOH X O 1 |
| HETATM 2672 O O . HOH C 3 . ? 30.243 28.068 6.568 1.00 44.17 ? 886 HOH X O 1 |
| HETATM 2673 O O . HOH C 3 . ? 31.010 27.606 -1.596 1.00 25.98 ? 887 HOH X O 1 |
| HETATM 2674 O O . HOH C 3 . ? 33.691 19.888 -0.463 1.00 26.68 ? 888 HOH X O 1 |
| HETATM 2675 O O . HOH C 3 . ? 6.861 3.803 19.390 1.00 36.12 ? 889 HOH X O 1 |
| HETATM 2676 O O . HOH C 3 . ? 12.137 28.539 -9.532 1.00 34.28 ? 890 HOH X O 1 |
| HETATM 2677 O O . HOH C 3 . ? 4.393 3.245 19.146 1.00 41.85 ? 891 HOH X O 1 |
| HETATM 2678 O O . HOH C 3 . ? 26.074 25.803 14.236 1.00 37.62 ? 892 HOH X O 1 |
| HETATM 2679 O O . HOH C 3 . ? -0.471 27.230 8.064 1.00 33.42 ? 893 HOH X O 1 |
| HETATM 2680 O O . HOH C 3 . ? 8.208 0.811 16.982 1.00 37.83 ? 894 HOH X O 1 |
| HETATM 2681 O O . HOH C 3 . ? 25.722 27.160 -13.500 1.00 36.94 ? 895 HOH X O 1 |
| HETATM 2682 O O . HOH C 3 . ? 30.791 25.531 7.341 1.00 36.00 ? 896 HOH X O 1 |
| HETATM 2683 O O . HOH C 3 . ? 8.709 26.595 -8.334 1.00 34.37 ? 897 HOH X O 1 |
| HETATM 2684 O O . HOH C 3 . ? 29.795 27.196 11.679 1.00 42.87 ? 898 HOH X O 1 |
| HETATM 2685 O O . HOH C 3 . ? 34.230 9.343 24.063 1.00 46.70 ? 899 HOH X O 1 |
| HETATM 2686 O O . HOH C 3 . ? 31.576 9.454 -10.796 1.00 45.37 ? 900 HOH X O 1 |
| HETATM 2687 O O . HOH C 3 . ? 8.090 36.318 -0.703 1.00 36.59 ? 901 HOH X O 1 |
| HETATM 2688 O O . HOH C 3 . ? -0.514 7.914 15.177 1.00 40.39 ? 902 HOH X O 1 |
| HETATM 2689 O O . HOH C 3 . ? 22.802 4.774 28.014 1.00 45.37 ? 903 HOH X O 1 |
| HETATM 2690 O O . HOH C 3 . ? 23.991 7.236 27.663 1.00 40.94 ? 904 HOH X O 1 |
| HETATM 2691 O O . HOH C 3 . ? 21.741 5.695 30.714 1.00 43.08 ? 905 HOH X O 1 |
| HETATM 2692 O O . HOH C 3 . ? 26.710 37.096 5.678 1.00 44.87 ? 906 HOH X O 1 |
| HETATM 2693 O O . HOH C 3 . ? 8.324 38.942 5.681 1.00 41.55 ? 907 HOH X O 1 |
| HETATM 2694 O O . HOH C 3 . ? 11.672 42.183 5.951 1.00 49.42 ? 908 HOH X O 1 |
| HETATM 2695 O O . HOH C 3 . ? 18.047 18.996 27.290 1.00 42.63 ? 909 HOH X O 1 |
| HETATM 2696 O O . HOH C 3 . ? 2.486 16.036 -0.174 1.00 50.34 ? 910 HOH X O 1 |
| HETATM 2697 O O . HOH C 3 . ? 4.924 33.536 7.496 1.00 27.37 ? 911 HOH X O 1 |
| HETATM 2698 O O . HOH C 3 . ? 18.443 45.224 -2.685 1.00 21.99 ? 912 HOH X O 1 |
| HETATM 2699 O O . HOH C 3 . ? 34.602 13.522 16.590 1.00 45.64 ? 913 HOH X O 1 |
| HETATM 2700 O O . HOH C 3 . ? 26.907 16.858 23.466 1.00 38.28 ? 914 HOH X O 1 |
| HETATM 2701 O O . HOH C 3 . ? 31.669 2.876 21.432 1.00 42.73 ? 915 HOH X O 1 |
| HETATM 2702 O O . HOH C 3 . ? 13.932 30.087 28.866 1.00 52.49 ? 916 HOH X O 1 |
| HETATM 2703 O O . HOH C 3 . ? 34.295 2.283 -1.896 1.00 39.01 ? 917 HOH X O 1 |
| HETATM 2704 O O . HOH C 3 . ? 37.275 17.756 -5.664 1.00 41.60 ? 918 HOH X O 1 |
| HETATM 2705 O O . HOH C 3 . ? 16.124 24.624 -14.159 1.00 38.48 ? 919 HOH X O 1 |
| HETATM 2706 O O . HOH C 3 . ? 1.074 16.685 -8.717 1.00 42.81 ? 920 HOH X O 1 |
| HETATM 2707 O O . HOH C 3 . ? 9.227 24.418 26.943 1.00 49.35 ? 921 HOH X O 1 |
| HETATM 2708 O O . HOH C 3 . ? 32.799 15.429 14.246 1.00 23.08 ? 922 HOH X O 1 |
| HETATM 2709 O O . HOH D 3 . ? 9.372 8.601 6.496 1.00 13.21 ? 85 HOH P O 1 |
| HETATM 2710 O O . HOH D 3 . ? -13.108 7.649 6.435 1.00 20.77 ? 86 HOH P O 1 |
| HETATM 2711 O O . HOH D 3 . ? 0.401 9.043 1.078 1.00 35.81 ? 87 HOH P O 1 |
| HETATM 2712 O O . HOH D 3 . ? 5.674 10.711 4.456 1.00 17.74 ? 88 HOH P O 1 |
| HETATM 2713 O O . HOH D 3 . ? -6.710 7.160 1.463 1.00 39.18 ? 89 HOH P O 1 |
| HETATM 2714 O O . HOH D 3 . ? 8.430 5.217 -5.153 1.00 28.38 ? 90 HOH P O 1 |
| HETATM 2715 O O . HOH D 3 . ? -7.328 5.482 -1.728 1.00 33.00 ? 91 HOH P O 1 |
| HETATM 2716 O O . HOH D 3 . ? 5.683 11.945 -2.250 1.00 25.21 ? 92 HOH P O 1 |
| HETATM 2717 O O . HOH D 3 . ? 5.272 13.521 1.132 1.00 25.44 ? 93 HOH P O 1 |
| HETATM 2718 O O . HOH D 3 . ? 2.460 10.602 2.668 1.00 28.89 ? 94 HOH P O 1 |
| HETATM 2719 O O . HOH D 3 . ? 5.983 14.498 -1.971 1.00 30.99 ? 95 HOH P O 1 |
| HETATM 2720 O O . HOH D 3 . ? -3.147 2.239 -2.542 1.00 38.11 ? 96 HOH P O 1 |
| HETATM 2721 O O . HOH D 3 . ? -18.494 8.247 7.322 1.00 27.11 ? 97 HOH P O 1 |
| HETATM 2722 O O . HOH D 3 . ? -12.725 8.119 2.572 1.00 30.49 ? 98 HOH P O 1 |
| HETATM 2723 O O . HOH D 3 . ? -1.133 4.023 -3.506 1.00 35.95 ? 99 HOH P O 1 |
| HETATM 2724 O O . HOH D 3 . ? -11.070 7.745 4.124 1.00 34.04 ? 100 HOH P O 1 |
| HETATM 2725 O O . HOH D 3 . ? -12.546 9.104 0.136 1.00 32.40 ? 101 HOH P O 1 |
| HETATM 2726 O O . HOH D 3 . ? -13.330 7.388 -1.626 1.00 36.37 ? 102 HOH P O 1 |
| HETATM 2727 O O . HOH D 3 . ? 5.047 1.265 4.169 1.00 22.66 ? 103 HOH P O 1 |
| HETATM 2728 O O . HOH D 3 . ? 3.556 10.048 -3.635 1.00 30.75 ? 104 HOH P O 1 |
| |
|
|
