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1960-03-15 | The comparison of 6-mercaptopurine with the combination of 6-mercaptopurine and azaserine in the treatment of acute leukemia in children: results of a cooperative study. | 14401649 | Mercaptopurine monotherapy | Azaserine and Mercaptopurine | Acute myeloid leukemia pediatric | Induction therapy | Could not be determined | Undesignated | no difference | Mercaptopurine monotherapy no difference to Azaserine and Mercaptopurine for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,960 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1966-01-17 | Vinblastine sulfate vs cyclophosphamide in the therapy for lymphoma. | 5322863 | Cyclophosphamide monotherapy | Vinblastine monotherapy | Classical Hodgkin lymphoma | Induction therapy | ORR | Undesignated | inferior | Cyclophosphamide monotherapy inferior to Vinblastine monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,966 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1966-03-15 | A controlled trial of urethane treatment in multiple myeloma. | 5933438 | Urethane monotherapy | Placebo | Multiple myeloma | Non-curative therapy | OS | Undesignated | inferior | Urethane monotherapy inferior to Placebo for Multiple myeloma (Non-curative therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,966 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1966-09-01 | Chemotherapy of acute leukemia in childhood. Comparison of cyclophosphamide and mercaptopurine. | 5917939 | Cyclophosphamide and Prednisone | Mercaptopurine and Prednisone | B-cell acute lymphoblastic leukemia pediatric | Induction therapy | Could not be determined | Undesignated | no difference | Cyclophosphamide and Prednisone no difference to Mercaptopurine and Prednisone for B-cell acute lymphoblastic leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,966 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1968-02-05 | Mechlorethamine HCl and cyclophosphamide in the treatment of Hodgkin's disease and the lymphomas. | 4865234 | Mechlorethamine monotherapy | Cyclophosphamide monotherapy | Classical Hodgkin lymphoma | Induction therapy | ORR | Primary | no difference | Mechlorethamine monotherapy no difference to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,968 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1968-09-15 | Ten year follow-up results of patients with carcinoma of the breast in a co-operative clinical trial evaluating surgical adjuvant chemotherapy. In 1958, a co-operative clinical trial, involving 23 institutions, was begun to evaluate the efficacy of a short course of triethylenethiophosphoramide as an adjuvant to radica... | 805475;4970947 | Placebo | Thiotepa monotherapy | Breast cancer | Adjuvant therapy | RR | Primary | no difference | Placebo no difference to Thiotepa monotherapy for Breast cancer (Adjuvant therapy) [endpoint: RR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,968 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy superior to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: PFS] | false |
1969-02-15 | Combination chemotherapy in lymphosarcoma and reticulum cell sarcoma. | 4886120 | Cyclophosphamide monotherapy | CVP | Diffuse large B-cell lymphoma | Induction therapy | CR rate | Undesignated | inferior | Cyclophosphamide monotherapy inferior to CVP for Diffuse large B-cell lymphoma (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,969 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1969-02-17 | Cyclophosphamide vs melphalan in treatment of plasma cell myeloma. | 4179565 | Cyclophosphamide monotherapy | Melphalan monotherapy | Multiple myeloma | Non-curative first-line therapy | OS | Undesignated | no difference | Cyclophosphamide monotherapy no difference to Melphalan monotherapy for Multiple myeloma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,969 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1971-04-10 | Comparison of treatment policies in inoperable bronchial carcinoma. | 4101425 | Mechlorethamine and RT | Best supportive care | Non-small cell lung cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Mechlorethamine and RT no difference to Best supportive care for Non-small cell lung cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,971 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1971-04-10 | Comparison of treatment policies in inoperable bronchial carcinoma. | 4101425 | Mechlorethamine monotherapy | Best supportive care | Non-small cell lung cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Mechlorethamine monotherapy no difference to Best supportive care for Non-small cell lung cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,971 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1971-04-10 | Comparison of treatment policies in inoperable bronchial carcinoma. | 4101425 | Best supportive care | Radiation therapy | Non-small cell lung cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Best supportive care no difference to Radiation therapy for Non-small cell lung cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,971 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1972-01-15 | Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study. In 1961, a randomized study was begun at the University of Wisconsin Medical Center in which the treatment of advanced squamous cell carcinoma of the head and neck with radiation the... | 175693;4550551 | Fluorouracil and RT | Radiation therapy | Head and neck cancer | Definitive therapy | OS | Undesignated | superior | Fluorouracil and RT superior to Radiation therapy for Head and neck cancer (Definitive therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,972 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | No induction inferior to Cisplatin and Epirubicin for Nasopharyngeal carcinoma (Induction therapy) [endpoint: OS] | false |
1972-08-15 | Combination chemotherapy for multiple myeloma. | 5051662 | Melphalan and Prednisone (MP) | MPP | Multiple myeloma | Non-curative first-line therapy | OS | Undesignated | no difference | Melphalan and Prednisone (MP) no difference to MPP for Multiple myeloma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,972 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1973-06-16 | Maintenance chemotherapy for advanced Hodgkin's disease in remission. | 4122739 | Carmustine monotherapy | Observation | Classical Hodgkin lymphoma | Consolidation after upfront therapy | Could not be determined | Undesignated | no difference | Carmustine monotherapy no difference to Observation for Classical Hodgkin lymphoma (Consolidation after upfront therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,973 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1973-06-16 | Maintenance chemotherapy for advanced Hodgkin's disease in remission. | 4122739 | MOPP | Observation | Classical Hodgkin lymphoma | Consolidation after upfront therapy | Could not be determined | Undesignated | no difference | MOPP no difference to Observation for Classical Hodgkin lymphoma (Consolidation after upfront therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,973 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1973-09-03 | Multiple chemotherapeutic agents for Hodgkin disease. Comparison of three routines: a cooperative study by acute leukemia group B. | 4740983 | ALB | MOPP | Classical Hodgkin lymphoma | Induction therapy | ORR | Undesignated | inferior | ALB inferior to MOPP for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,973 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1973-09-03 | Multiple chemotherapeutic agents for Hodgkin disease. Comparison of three routines: a cooperative study by acute leukemia group B. | 4740983 | SEQ | MOPP | Classical Hodgkin lymphoma | Induction therapy | ORR | Undesignated | inferior | SEQ inferior to MOPP for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,973 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1974-02-15 | Proceedings: Daunorubicin cardiac toxicity in children with acute lymphocytic leukemia. | 4521474 | Vincristine and Prednisone | Daunorubicin, Vincristine, Prednisolone | B-cell acute lymphoblastic leukemia pediatric | Induction therapy | CR rate | Primary | no difference | Vincristine and Prednisone no difference to Daunorubicin, Vincristine, Prednisolone for B-cell acute lymphoblastic leukemia pediatric (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,974 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1974-02-15 | Proceedings: Daunorubicin cardiac toxicity in children with acute lymphocytic leukemia. | 4521474 | Vincristine and Prednisone | Daunorubicin, Vincristine, Prednisone | B-cell acute lymphoblastic leukemia pediatric | Induction therapy | CR rate | Primary | no difference | Vincristine and Prednisone no difference to Daunorubicin, Vincristine, Prednisone for B-cell acute lymphoblastic leukemia pediatric (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,974 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1974-02-15 | Proceedings: Superiority of adriamycin over oral nitrosoureas in patients with advanced breast carcinoma. A Southwest Cancer Chemotherapy study Group study. | 4812769 | Doxorubicin monotherapy | Semustine monotherapy | Breast cancer | Non-curative first-line therapy | OS | Undesignated | superior | Doxorubicin monotherapy superior to Semustine monotherapy for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,974 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1974-02-15 | Proceedings: Superiority of adriamycin over oral nitrosoureas in patients with advanced breast carcinoma. A Southwest Cancer Chemotherapy study Group study. | 4812769 | Doxorubicin monotherapy | Lomustine monotherapy | Breast cancer | Non-curative first-line therapy | OS | Undesignated | superior | Doxorubicin monotherapy superior to Lomustine monotherapy for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,974 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1974-11-15 | Combination chemotherapy of lymphomas other than Hodgkin's disease. | 4608355 | Vincristine and Prednisone (VP) | C-MOPP | Diffuse large B-cell lymphoma | Induction therapy | CR rate | Undesignated | inferior | Vincristine and Prednisone (VP) inferior to C-MOPP for Diffuse large B-cell lymphoma (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,974 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1974-12-05 | Delay in progression of malignant lymphoma after BCG vaccination. | 4609380 | BCG vaccine monotherapy | Observation | Classical Hodgkin lymphoma | Maintenance after upfront therapy | PFS | Undesignated | superior | BCG vaccine monotherapy superior to Observation for Classical Hodgkin lymphoma (Maintenance after upfront therapy) [endpoint: PFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,974 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1975-01-15 | Remission maintenance therapy for multiple myeloma. The effects of various regimens of melphalan combination chemotherapy were evaluated in 508 patients with multiple myeloma. No value was confirmed from the addition of procarbazine or vincristine sulfate to melphalan-prednisone combinations. Ninety-six patients who re... | 1111463 | Observation | Carmustine and Prednisone | Multiple myeloma | Non-curative first-line maintenance therapy | Could not be determined | Undesignated | no difference | Observation no difference to Carmustine and Prednisone for Multiple myeloma (Non-curative first-line maintenance therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1975-01-15 | Remission maintenance therapy for multiple myeloma. The effects of various regimens of melphalan combination chemotherapy were evaluated in 508 patients with multiple myeloma. No value was confirmed from the addition of procarbazine or vincristine sulfate to melphalan-prednisone combinations. Ninety-six patients who re... | 1111463 | Melphalan and Prednisone (MP) | Observation | Multiple myeloma | Non-curative first-line maintenance therapy | Could not be determined | Undesignated | no difference | Melphalan and Prednisone (MP) no difference to Observation for Multiple myeloma (Non-curative first-line maintenance therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1975-01-16 | L-phenylalanine mustard (L-PAM) in the management of primary breast cancer. An update of earlier findings and a comparison with those utilizing L-PAM plus 5-fluorouracil (5-FU).
L-Phenylalanine mustard (L-PAM) in the management of primary breast cancer. A report of early findings. Prolonged l-phenylalanine mustard (L-... | 194679;1105174;3519883 | Melphalan monotherapy | Placebo | Breast cancer | Adjuvant therapy | DFS | Undesignated | superior | Melphalan monotherapy superior to Placebo for Breast cancer (Adjuvant therapy) [endpoint: DFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1975-07-15 | Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP. This paper reports the preliminary results of a controlled study randomizing MOPP vs. a new four-drug combination (ABVD) in advanced Hodgkin's disease. ABVD consists of 6 cycles of adriamycin, b... | 54209 | MOPP | ABVD | Classical Hodgkin lymphoma | Induction therapy | Could not be determined | Undesignated | no difference | MOPP no difference to ABVD for Classical Hodgkin lymphoma (Induction therapy) [endpoint: Could not be determined] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1975-12-13 | Treatment of inoperable carcinoma of bronchus. A randomised prospective trial comparing "no immediate treatment" with single and multiple agent chemotherapy in 188 patients with inoperable carcinoma of the bronchus is reported. No immediate treatment proved a significantly better policy both for patients' survival and ... | 53654 | Procarbazine monotherapy | Best supportive care | Non-small cell lung cancer | Non-curative first-line therapy | OS | Undesignated | inferior | Procarbazine monotherapy inferior to Best supportive care for Non-small cell lung cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1975-12-13 | Treatment of inoperable carcinoma of bronchus. A randomised prospective trial comparing "no immediate treatment" with single and multiple agent chemotherapy in 188 patients with inoperable carcinoma of the bronchus is reported. No immediate treatment proved a significantly better policy both for patients' survival and ... | 53654 | MVPP | Best supportive care | Non-small cell lung cancer | Non-curative first-line therapy | OS | Undesignated | inferior | MVPP inferior to Best supportive care for Non-small cell lung cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1975-12-15 | Chemotherapy of advanced breast cancer: a controlled randomized trial of cyclophosphamide versus a four-drug combination. Ninety-nine patients with advanced breast cancer were randomized to receive either cyclophosphamide continuously or a combination of cyclophosphamide, methotrexate, 5-fluorouracil and vinblastine gi... | 766800 | CMFV | Cyclophosphamide monotherapy | Breast cancer | Non-curative therapy | ORR | Primary | no difference | CMFV no difference to Cyclophosphamide monotherapy for Breast cancer (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,975 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1976-01-29 | Adjuvant immunotherapy with BCG in treatment of regional-lymph-node metastases from malignant melanoma. Despite current surgical therapy, about 80 per cent of patients with malignant melanoma metastatic to lymph nodes succumb to systemic metastatic disease. To determine if postoperative adjuvant immunization with BCG w... | 1244548 | Observation | BCG vaccine monotherapy | Melanoma | Adjuvant therapy | MFS | Undesignated | inferior | Observation inferior to BCG vaccine monotherapy for Melanoma (Adjuvant therapy) [endpoint: MFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Ipilimumab monotherapy superior to gp100 vaccine for Melanoma (Advanced Unresectable or Metastatic, Unresectable or Metastatic) (Non-curative therapy) [endpoint: OS] | false |
1976-01-31 | Levamisole in advanced human breast cancer. A clinical trial of levamisole, an orally effective modifier of the immune response, is reported in women with primary inoperable breast cancer (stage III). After being rendered clinically disease-free by radiotherapy to the breast, supraclavicular area, and axilla, patients ... | 55529 | Observation | Levamisole monotherapy | Breast cancer | Adjuvant therapy | OS | Undesignated | inferior | Observation inferior to Levamisole monotherapy for Breast cancer (Adjuvant therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1976-02-19 | The CMF program for operable breast cancer with positive axillary nodes. Updated analysis on the disease-free interval, site of relapse and drug tolerance. In a prospective randomized study adjuvant combination chemotherapy with CMF was administered for 12 monthly cycles to 207 patients subjected to radical mastectomy ... | 326384;1246307;3839424;7877646 | Observation | CMF | Breast cancer | Adjuvant therapy | RFS | Undesignated | inferior | Observation inferior to CMF for Breast cancer (Adjuvant therapy) [endpoint: RFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1976-02-21 | Regional immunotherapy of lung cancer with intrapleural B.C.G. 60 patients have been entered into a randomised prospective study to answer the question-does a single postoperative injection of B.C.G. into the pleural space improve survival after surgery for lung cancer? 40 patients have been followed up for more than a... | 55646 | Observation | Intrapleural BCG | Non-small cell lung cancer | Adjuvant therapy | OS | Undesignated | inferior | Observation inferior to Intrapleural BCG for Non-small cell lung cancer (Adjuvant therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1976-02-21 | A 5-year controlled study of B.C.G. and radiotherapy inoperable lung cancer. Forty-eight patients with advanced squamous-cell lung cancer were treated with radical radiotherapy. Thereafter twenty-five received B.C.G. regularly and twenty-three did not. Differences in survival during the first year of observation and ab... | 55647 | BCG vaccine monotherapy | Observation | Non-small cell lung cancer | Maintenance after upfront therapy | OS | Undesignated | superior | BCG vaccine monotherapy superior to Observation for Non-small cell lung cancer (Maintenance after upfront therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1976-02-21 | A 5-year controlled study of B.C.G. and radiotherapy inoperable lung cancer. Forty-eight patients with advanced squamous-cell lung cancer were treated with radical radiotherapy. Thereafter twenty-five received B.C.G. regularly and twenty-three did not. Differences in survival during the first year of observation and ab... | 55647 | Observation | BCG vaccine monotherapy | Non-small cell lung cancer | Consolidation after upfront therapy | OS | Undesignated | inferior | Observation inferior to BCG vaccine monotherapy for Non-small cell lung cancer (Consolidation after upfront therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1976-04-03 | Response and survival in advanced breast cancer after two non-cross-resistant combinations. A prospective study with two cytotoxic combinations (cyclophosphamide, methotrexate, and fluorouracil (CMF), and adriamycin plus vincristine (AV)) was carried out in 110 patients with advanced breast cancer. There was no signifi... | 1260337 | CMF | Doxorubicin and Vincristine (AV) | Breast cancer | Non-curative first-line therapy | ORR | Primary | no difference | CMF no difference to Doxorubicin and Vincristine (AV) for Breast cancer (Non-curative first-line therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1976-06-17 | Radiation and high-dose metronidazole in supratentorial glioblastomas. We used "high-dose" metronidazole, an "in vitro" and "in vivo" specific radiosensitizer of hypoxic cells, in a controlled trial to evaluate possible enhancement of radiation effect in patients with supratentorial glioblastomas. Thirty-six patients w... | 177873 | Metronidazole and RT | Radiation therapy | Glioblastoma | Non-curative first-line therapy | OS | Undesignated | superior | Metronidazole and RT superior to Radiation therapy for Glioblastoma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | 8-in-1 inferior to VCP for Medulloblastoma (All lines of therapy) [endpoint: PFS] | false |
1976-06-28 | Chemoprophylaxis for patients with colorectal cancer. Prospective study with five-year follow-up. The effectiveness of a short-term fluorouracil chemopophylaxis regimen commencing four to six weeks after "curative" surgery was evaluated in a homogeneous group of 213 patients with colorectal cancer. In stage III disease... | 946987 | Observation | Fluorouracil monotherapy | Colon cancer | Adjuvant therapy | DFS | Undesignated | inferior | Observation inferior to Fluorouracil monotherapy for Colon cancer (Adjuvant therapy) [endpoint: DFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Fluorouracil and Semustine superior to Fluorouracil monotherapy for Colorectal cancer (Non-curative first-line therapy) [endpoint: ORR] | false |
1976-07-15 | Phase III comparison of the treatment of advanced gastrointestinal cancer with bolus weekly 5-FU vs. methyl-CCNU plus bolus weekly 5-FU. A Southwest Oncology Group study. In a randomized and stratified study, 294 patients with advanced gastrointestinal cancer were treated either with 5-fluorouracil (5-FU) 400 mg/m2 wee... | 779949 | Fluorouracil monotherapy | Fluorouracil and Semustine | Colorectal cancer | Non-curative first-line therapy | ORR | Undesignated | inferior | Fluorouracil monotherapy inferior to Fluorouracil and Semustine for Colorectal cancer (Non-curative first-line therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Fluorouracil monotherapy superior to Observation for Colon cancer (Adjuvant therapy) [endpoint: DFS] | false |
1976-07-15 | Combination chemotherapy and adriamycin in patients with advanced breast cancer. A Southwest Oncology Group study. In January, 1972, the Southwest Oncology Group initiated two randomized studies for patients with advanced breast cancer. The study for patients with prior chemotherapy showed a 33% response rate with adri... | 947510 | CMFVP | Doxorubicin monotherapy | Breast cancer | Non-curative therapy | ORR | Undesignated | superior | CMFVP superior to Doxorubicin monotherapy for Breast cancer (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1976-07-15 | Combination chemotherapy and adriamycin in patients with advanced breast cancer. A Southwest Oncology Group study. In January, 1972, the Southwest Oncology Group initiated two randomized studies for patients with advanced breast cancer. The study for patients with prior chemotherapy showed a 33% response rate with adri... | 947510 | CMFVP | Doxorubicin monotherapy | Breast cancer | Non-curative first-line therapy | ORR | Undesignated | superior | CMFVP superior to Doxorubicin monotherapy for Breast cancer (Non-curative first-line therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1976-08-15 | The treatment of Wilms' tumor: Results of the national Wilms' tumor study. The National Wilms' Tumor Study, initiated in 1969, tested competing treatment strategems for patients with tumors ranging from Group (Gp) I (tumors confined to the kidney and totally removed) to Gp IV (remote metastases present at diagnosis). T... | 184912 | Vincristine monotherapy | Dactinomycin and Vincristine | Wilms tumor | Adjuvant therapy | RFS | Undesignated | inferior | Vincristine monotherapy inferior to Dactinomycin and Vincristine for Wilms tumor (Adjuvant therapy) [endpoint: RFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Cyproterone acetate monotherapy superior to Estradiol undecylate monotherapy for Prostate cancer (Non-curative therapy) [endpoint: ORR] | false |
1976-08-15 | The treatment of Wilms' tumor: Results of the national Wilms' tumor study. The National Wilms' Tumor Study, initiated in 1969, tested competing treatment strategems for patients with tumors ranging from Group (Gp) I (tumors confined to the kidney and totally removed) to Gp IV (remote metastases present at diagnosis). T... | 184912 | Dactinomycin and Vincristine | Dactinomycin monotherapy | Wilms tumor | Adjuvant therapy | RFS | Undesignated | superior | Dactinomycin and Vincristine superior to Dactinomycin monotherapy for Wilms tumor (Adjuvant therapy) [endpoint: RFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Estradiol undecylate monotherapy inferior to Cyproterone acetate monotherapy for Prostate cancer (Non-curative therapy) [endpoint: ORR] | false |
1976-10-15 | Hydroxyldaunomycin (Adriamycin) combination chemotherapy in malignant lymphoma. Combination chemotherapy with CHOP (cyclophosphamide, Adriamycin, vincristine, and prednisone) and HOP (Adrimycin, vincristine, and prednisone, was used as treatment for patients with pathologically staged, advanced non-Hodgkin's lymphoma. ... | 791473 | CHOP | HOP | Diffuse large B-cell lymphoma | Induction therapy | OS | Undesignated | no difference | CHOP no difference to HOP for Diffuse large B-cell lymphoma (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1976-11-06 | Initial treatment of stage IIIA Hodgkin's disease. Comparison of radiotherapy with combined chemotherapy. British National Lymphoma Investigation. 117 patients with stage IIIA Hodgkin's disease were randomly allocated for treatment in a multicentre trial comparing the results of total nodal irradiation (T.N.I.) with th... | 62265 | MOPP | Radiation therapy | Classical Hodgkin lymphoma | Induction therapy | DFS | Undesignated | inferior | MOPP inferior to Radiation therapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: DFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1976-11-15 | Combination chemotherapy for metastatic breast carcinoma. Prospective comparison of multiple drug therapy with L-phenylalanine mustard. A prospective randomized clinical trial was undertaken in 184 patients with metastatic breast carcinoma to compare single drug chemotherapy with L-phenylalanine mustard (L-PAM) and int... | 991103 | CMF | Melphalan monotherapy | Breast cancer | Non-curative therapy | OS | Undesignated | superior | CMF superior to Melphalan monotherapy for Breast cancer (Non-curative therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1976-11-15 | Combination chemotherapy for metastatic breast carcinoma. Prospective comparison of multiple drug therapy with L-phenylalanine mustard. A prospective randomized clinical trial was undertaken in 184 patients with metastatic breast carcinoma to compare single drug chemotherapy with L-phenylalanine mustard (L-PAM) and int... | 991103 | Melphalan monotherapy | CMF | Breast cancer | Non-curative first-line therapy | OS | Undesignated | inferior | Melphalan monotherapy inferior to CMF for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,976 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMFT and BCG no difference to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | false |
1977-06-15 | L-phenylalanine mustard (L-PAM) in the management of primary breast cancer. An update of earlier findings and a comparison with those utilizing L-PAM plus 5-fluorouracil (5-FU). | 194679 | PF | Melphalan monotherapy | Breast cancer | Adjuvant therapy | RFS | Undesignated | superior | PF superior to Melphalan monotherapy for Breast cancer (Adjuvant therapy) [endpoint: RFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1977-07-01 | Cyclophosphamide, vincristine, and prednisone (CVP) versus adriamycin, bleomycin, and prednisone (ABP) in stage IV non-Hodgkin's lymphomas. In stage IV non-Hodgkin's lymphomas, CVP (cyclophosphamide, vincristine, and prednisone) was randomly compared to ABP (adriamycin, bleomycin, and prednisone). Of 62 patients entere... | 65728 | ABP | CVP | Diffuse large B-cell lymphoma | Induction therapy | ORR | Undesignated | no difference | ABP no difference to CVP for Diffuse large B-cell lymphoma (Induction therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1977-08-15 | A comparison of cyclophosphamide, adriamycin, 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisone (CMFVP) in patients with metastatic breast cancer: a Southeastern Cancer Study Group project. In an ongoing prospective randomized study, 113 evaluable patients have received ei... | 329975;6688538 | CMFVP | FAC | Breast cancer | Non-curative therapy | OS | Undesignated | inferior | CMFVP inferior to FAC for Breast cancer (Non-curative therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMFT and BCG no difference to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | false |
1977-08-15 | A comparison of cyclophosphamide, adriamycin, 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisone (CMFVP) in patients with metastatic breast cancer: a Southeastern Cancer Study Group project. In an ongoing prospective randomized study, 113 evaluable patients have received ei... | 329975;6688538 | FAC | CMFVP | Breast cancer | Non-curative first-line therapy | OS | Undesignated | superior | FAC superior to CMFVP for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1977-08-18 | An evaluation of early or delayed adjuvant chemotherapy in premenopausal patients with advanced breast cancer undergoing oophorectomy. We treated randomly 75 premenopausal patients with advanced breast cancer with combination chemotherapy (5-fluorouracil, cyclophosphamide and prednisone), either as an early adjunct to ... | 876327 | CFP and Bilateral oophorectomy | Bilateral oophorectomy monotherapy | Breast cancer | Adjuvant therapy | PFS | Undesignated | superior | CFP and Bilateral oophorectomy superior to Bilateral oophorectomy monotherapy for Breast cancer (Adjuvant therapy) [endpoint: PFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1977-08-18 | An evaluation of early or delayed adjuvant chemotherapy in premenopausal patients with advanced breast cancer undergoing oophorectomy. We treated randomly 75 premenopausal patients with advanced breast cancer with combination chemotherapy (5-fluorouracil, cyclophosphamide and prednisone), either as an early adjunct to ... | 876327 | Bilateral oophorectomy | CFP and Bilateral oophorectomy | Breast cancer | Adjuvant therapy | PFS | Undesignated | inferior | Bilateral oophorectomy inferior to CFP and Bilateral oophorectomy for Breast cancer (Adjuvant therapy) [endpoint: PFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1977-09-15 | Combination intrathecal therapy for meningeal leukemia: two versus three drugs. The comparative effectiveness of intrathecal (IT) combination chemotherapy using two agents, methotrexate (MTX) and hydrocortisone (HDC), and three agents, MTX, HDC, and cytosine arabinoside (CA), in treating meningeal leukemia was determin... | 577889 | IT Methotrexate and Hydrocortisone | IT MTX, Ara-C, HC | CNS leukemia | Local therapy | DOR | Primary | no difference | IT Methotrexate and Hydrocortisone no difference to IT MTX, Ara-C, HC for CNS leukemia (Local therapy) [endpoint: DOR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1977-11-15 | The intergroup rhabdomyosarcoma study: a preliminary report.
The Intergroup Rhabdomyosarcoma Study-I. A final report. The results of treatment of 686, previously untreated patients younger than 21 years with rhabdomyosarcoma or undifferentiated sarcoma, who were entered on Intergroup Rhabdomyosarcoma Study-I (IRS-I) w... | 336175;3275486 | VAC and RT | VAC | Rhabdomyosarcoma | All lines of therapy | OS | Co-primary | no difference | VAC and RT no difference to VAC for Rhabdomyosarcoma (All lines of therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Melphalan and Vincristine inferior to Doxorubicin monotherapy for Soft tissue sarcoma (Non-curative therapy) [endpoint: ORR] | false |
1977-12-15 | Combination therapy for multiple myeloma. The effect of six different chemotherapy regimens were evaluated in 462 previously untreated patients with multiple myeloma. In comparison with other treatments, drug combinations that included vincristine and were given at 3-week intervals were associated with higher response ... | 589554 | Alkylator-prednisone combinations | VMCP | Multiple myeloma | Non-curative first-line therapy | OS | Undesignated | inferior | Alkylator-prednisone combinations inferior to VMCP for Multiple myeloma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,977 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1978-04-29 | Repeated adjuvant chemotherapy with phenylalanine mustard or 5-fluorouracil, cyclophosphamide, and prednisone with or without radiation, after mastectomy for breast cancer. 172 patients who had had mastectomy for breast cancer were treated by repeated adjuvant chemotherapy, either with phenylalanine mustard (P.A.M.) or... | 76842 | Melphalan monotherapy | CFP | Breast cancer | Adjuvant therapy | OS | Undesignated | inferior | Melphalan monotherapy inferior to CFP for Breast cancer (Adjuvant therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1978-05-15 | A randomized comparative trial of adriamycin versus methotrexate in combination drug therapy. A prospective randomized trial was conducted comparing the clinical response of 78 previously untreated patients with advanced metastatic breast cancer to a combination of cyclophosphamide, methotrexate, and 5-fluorouracil (CM... | 348293 | CMF | FAC | Breast cancer | Non-curative first-line therapy | ORR | Undesignated | inferior | CMF inferior to FAC for Breast cancer (Non-curative first-line therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMFT and BCG no difference to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | false |
1978-06-15 | Adriamycin in combination for the treatment of breast cancer: a Southwest Oncology Group study. Patients with advanced breast cancer who had not previously received chemotherapy were treated on a three-arm prospective study: adriamycin day 1 plus 5-FU on day 1 and 8 (AF), adriamycin day 1, plus 5-FU day 1 and 8, and cy... | 657081 | FAC | CAMF | Breast cancer | Non-curative first-line therapy | ORR | Primary | no difference | FAC no difference to CAMF for Breast cancer (Non-curative first-line therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1978-06-15 | Adriamycin in combination for the treatment of breast cancer: a Southwest Oncology Group study. Patients with advanced breast cancer who had not previously received chemotherapy were treated on a three-arm prospective study: adriamycin day 1 plus 5-FU on day 1 and 8 (AF), adriamycin day 1, plus 5-FU day 1 and 8, and cy... | 657081 | CAMF | FAC | Breast cancer | Non-curative therapy | ORR | Primary | no difference | CAMF no difference to FAC for Breast cancer (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1978-06-15 | Adriamycin in combination for the treatment of breast cancer: a Southwest Oncology Group study. Patients with advanced breast cancer who had not previously received chemotherapy were treated on a three-arm prospective study: adriamycin day 1 plus 5-FU on day 1 and 8 (AF), adriamycin day 1, plus 5-FU day 1 and 8, and cy... | 657081 | Doxorubicin and Fluorouracil (FA) | FAC | Breast cancer | Non-curative first-line therapy | ORR | Primary | no difference | Doxorubicin and Fluorouracil (FA) no difference to FAC for Breast cancer (Non-curative first-line therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1978-06-15 | Adriamycin in combination for the treatment of breast cancer: a Southwest Oncology Group study. Patients with advanced breast cancer who had not previously received chemotherapy were treated on a three-arm prospective study: adriamycin day 1 plus 5-FU on day 1 and 8 (AF), adriamycin day 1, plus 5-FU day 1 and 8, and cy... | 657081 | Doxorubicin and Fluorouracil (FA) | CAMF | Breast cancer | Non-curative therapy | ORR | Primary | no difference | Doxorubicin and Fluorouracil (FA) no difference to CAMF for Breast cancer (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1978-09-15 | Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. A controlled, prospective, randomized study evaluated the use of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or radiotherapy in the treatment of patients who were operated on and had histological confirmatio... | 355604 | Radiation therapy | Best supportive care | Glioblastoma | Non-curative first-line therapy | OS | Undesignated | superior | Radiation therapy superior to Best supportive care for Glioblastoma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | 8-in-1 inferior to VCP for Medulloblastoma (All lines of therapy) [endpoint: PFS] | false |
1978-09-15 | Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. A controlled, prospective, randomized study evaluated the use of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or radiotherapy in the treatment of patients who were operated on and had histological confirmatio... | 355604 | Radiation therapy | Carmustine monotherapy | Glioblastoma | Non-curative first-line therapy | OS | Undesignated | superior | Radiation therapy superior to Carmustine monotherapy for Glioblastoma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | 8-in-1 inferior to VCP for Medulloblastoma (All lines of therapy) [endpoint: PFS] | false |
1978-09-15 | Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. A controlled, prospective, randomized study evaluated the use of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or radiotherapy in the treatment of patients who were operated on and had histological confirmatio... | 355604 | Carmustine and RT | Radiation therapy | Glioblastoma | Non-curative first-line therapy | OS50% | Primary | no difference | Carmustine and RT no difference to Radiation therapy for Glioblastoma (Non-curative first-line therapy) [endpoint: OS50%] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | 8-in-1 inferior to VCP for Medulloblastoma (All lines of therapy) [endpoint: PFS] | false |
1978-10-15 | Primary systemic amyloidosis: comparison of melphalan and prednisone versus placebo. Satisfactory treatment for primary amyloidosis does not exist. Because the amyloid fibrils consist of a portion of a monoclonal light chain, it appears reasonable to treat amyloidosis with alkylating agents that are effective against t... | 356916 | Placebo | Melphalan and Prednisone (MP) | Light-chain (AL) amyloidosis | Non-curative first-line therapy | time on treatment | Undesignated | inferior | Placebo inferior to Melphalan and Prednisone (MP) for Light-chain (AL) amyloidosis (Non-curative first-line therapy) [endpoint: time on treatment] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Azaserine and Mercaptopurine no difference to Mercaptopurine monotherapy for Acute myeloid leukemia pediatric (Induction therapy) [endpoint: Could not be determined] | false |
1978-11-15 | Adriamycin versus methotrexate in five-drug combination chemotherapy for advanced breast cancer: a randomized trial. Adriamycin is of noteworthy efficacy in the treatment of metastatic breast cancer. Its role in combination regimens is under investigation. One hundred seventy-five women with advanced breast cancer were... | 363253 | CMFVP | CAFVP | Breast cancer | Non-curative therapy | OS | Undesignated | inferior | CMFVP inferior to CAFVP for Breast cancer (Non-curative therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMFT and BCG no difference to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | false |
1978-12-07 | Advanced ovarian adenocarcinoma. A prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy. Eighty patients with advanced ovarian adenocarcinoma were treated in a prospective, randomized trial comparing a four-drug combination--hexamethylmelamine, cyclophosphamide, methotrexate and 5-fluorouraci... | 101843 | Hexa-CAF | Melphalan monotherapy | Ovarian cancer | Non-curative first-line therapy | OS | Undesignated | superior | Hexa-CAF superior to Melphalan monotherapy for Ovarian cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Radiation therapy inferior to Hydroxyurea and RT for Cervical cancer (Definitive therapy) [endpoint: OS] | false |
1978-12-15 | Chemotherapy of advanced measurable colon and rectal carcinoma with oral 5-fluorouracil, alone or in combination with cyclophosphamide or 6-thioguanine, with intravenous 5-fluorouracil or beta-2'-deoxythioguanosine or with oral 3(4-methyl-cyclohexyl)-1(2-chlorethyl)-1-nitrosourea: a Phase II-III study of the Eastern Co... | 365312 | Semustine monotherapy | Fluorouracil monotherapy | Colorectal cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Semustine monotherapy no difference to Fluorouracil monotherapy for Colorectal cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Observation inferior to Fluorouracil monotherapy for Colon cancer (Adjuvant therapy) [endpoint: DFS] | false |
1978-12-15 | Chemotherapy of advanced measurable colon and rectal carcinoma with oral 5-fluorouracil, alone or in combination with cyclophosphamide or 6-thioguanine, with intravenous 5-fluorouracil or beta-2'-deoxythioguanosine or with oral 3(4-methyl-cyclohexyl)-1(2-chlorethyl)-1-nitrosourea: a Phase II-III study of the Eastern Co... | 365312 | Fluorouracil monotherapy | Cyclophosphamide and Fluorouracil | Colorectal cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Fluorouracil monotherapy no difference to Cyclophosphamide and Fluorouracil for Colorectal cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Observation inferior to Fluorouracil monotherapy for Colon cancer (Adjuvant therapy) [endpoint: DFS] | false |
1978-12-15 | Chemotherapy of advanced measurable colon and rectal carcinoma with oral 5-fluorouracil, alone or in combination with cyclophosphamide or 6-thioguanine, with intravenous 5-fluorouracil or beta-2'-deoxythioguanosine or with oral 3(4-methyl-cyclohexyl)-1(2-chlorethyl)-1-nitrosourea: a Phase II-III study of the Eastern Co... | 365312 | Fluorouracil and Thioguanine | Fluorouracil monotherapy | Colorectal cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Fluorouracil and Thioguanine no difference to Fluorouracil monotherapy for Colorectal cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,978 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Observation inferior to Fluorouracil monotherapy for Colon cancer (Adjuvant therapy) [endpoint: DFS] | false |
1979-02-15 | Superiority of adriamycin-containing combination chemotherapy in the treatment of diffuse lymphoma: a Southwest Oncology Group study. As a part of an ongoing prospective controlled trial, the Southwest Oncology Group compared the results of treatment of advanced non-Hodgkin's lymphoma with two CHOP regimens (cyclophosp... | 84706;6185212 | CHOP-BCG | COP-Bleo | Diffuse large B-cell lymphoma | Induction therapy | CR rate | Undesignated | superior | CHOP-BCG superior to COP-Bleo for Diffuse large B-cell lymphoma (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Urethane monotherapy inferior to Placebo for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1979-02-15 | Superiority of adriamycin-containing combination chemotherapy in the treatment of diffuse lymphoma: a Southwest Oncology Group study. As a part of an ongoing prospective controlled trial, the Southwest Oncology Group compared the results of treatment of advanced non-Hodgkin's lymphoma with two CHOP regimens (cyclophosp... | 84706;6185212 | COP-Bleo | CHOP-B | Diffuse large B-cell lymphoma | Induction therapy | CR rate | Undesignated | inferior | COP-Bleo inferior to CHOP-B for Diffuse large B-cell lymphoma (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1979-03-15 | Hydroxyurea or placebo combined with radiation to treat stages IIIB and IV cervical cancer confined to the pelvis. | 110744 | Radiation therapy | Hydroxyurea and RT | Cervical cancer | Definitive therapy | OS | Undesignated | inferior | Radiation therapy inferior to Hydroxyurea and RT for Cervical cancer (Definitive therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Hexa-CAF superior to Melphalan monotherapy for Ovarian cancer (Non-curative first-line therapy) [endpoint: OS] | false |
1979-04-27 | Thymosin fraction V and intensive combination chemotherapy. Prolonging the survival of patients with small-cell lung cancer. Patients with small-cell bronchogenic carcinoma who received intensive remission-induction chemotherapy randomly received either thymosin fraction V, 60 mg/sq m or 20 mg/sq m twice weekly, or no ... | 219267 | Cyclophosphamide, Lomustine, Methotrexate | Chemotherapy and Thymosin fraction V | Small cell lung cancer | Induction therapy | OS | Undesignated | inferior | Cyclophosphamide, Lomustine, Methotrexate inferior to Chemotherapy and Thymosin fraction V for Small cell lung cancer (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1979-07-01 | Combination chemotherapy for soft-tissue sarcomas: a phase III study. A total of 144 patients with advanced sarcomas were entered into a randomized prospective protocol with four treatment arms utilizing different combinations of chemotherapeutic agents. Of these, 120 patients (83%) were judged acceptable. Treatment 1:... | 376950 | Melphalan and Vincristine | Doxorubicin monotherapy | Soft tissue sarcoma | Non-curative therapy | ORR | Undesignated | inferior | Melphalan and Vincristine inferior to Doxorubicin monotherapy for Soft tissue sarcoma (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | VAC no difference to VAC and RT for Rhabdomyosarcoma (All lines of therapy) [endpoint: OS] | false |
1979-07-01 | Combination chemotherapy for soft-tissue sarcomas: a phase III study. A total of 144 patients with advanced sarcomas were entered into a randomized prospective protocol with four treatment arms utilizing different combinations of chemotherapeutic agents. Of these, 120 patients (83%) were judged acceptable. Treatment 1:... | 376950 | Actinomycin and Melphalan | Doxorubicin monotherapy | Soft tissue sarcoma | Non-curative therapy | ORR | Undesignated | inferior | Actinomycin and Melphalan inferior to Doxorubicin monotherapy for Soft tissue sarcoma (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | VAC no difference to VAC and RT for Rhabdomyosarcoma (All lines of therapy) [endpoint: OS] | false |
1979-07-01 | Combination chemotherapy for soft-tissue sarcomas: a phase III study. A total of 144 patients with advanced sarcomas were entered into a randomized prospective protocol with four treatment arms utilizing different combinations of chemotherapeutic agents. Of these, 120 patients (83%) were judged acceptable. Treatment 1:... | 376950 | Melphalan and 1-aminocyclopentanecarboxylic acid | Doxorubicin monotherapy | Soft tissue sarcoma | Non-curative therapy | ORR | Undesignated | inferior | Melphalan and 1-aminocyclopentanecarboxylic acid inferior to Doxorubicin monotherapy for Soft tissue sarcoma (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | VAC no difference to VAC and RT for Rhabdomyosarcoma (All lines of therapy) [endpoint: OS] | false |
1979-08-15 | Combination chemotherapy of metastatic breast cancer: a randomized trial comparing the use of adriamycin to that of Vinblastine. Two regimens of chemotherapy for metastatic breast cancer were compared in a randomized controlled fashion. Regimen 1 consisted of cyclophosphamide, vinblastine, methotrexate and 5-fluorourac... | 383254 | CMFV | CAMF | Breast cancer | Non-curative therapy | ORR | Primary | no difference | CMFV no difference to CAMF for Breast cancer (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMF inferior to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | false |
1979-10-04 | The chemotherapy of plasma-cell myeloma and the incidence of acute leukemia. Previously untreated patients with myeloma were randomized to initial treatment with melphalan and prednisone (and to cyclophosphamide or carmustine if relapse or progression occurred)(Group A, 125 patients), melphalan, cyclophosphamide, carmu... | 481481 | Melphalan and Prednisone (MP) | B/C/M | Multiple myeloma | Non-curative first-line therapy | OS | Primary | no difference | Melphalan and Prednisone (MP) no difference to B/C/M for Multiple myeloma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1979-10-04 | The chemotherapy of plasma-cell myeloma and the incidence of acute leukemia. Previously untreated patients with myeloma were randomized to initial treatment with melphalan and prednisone (and to cyclophosphamide or carmustine if relapse or progression occurred)(Group A, 125 patients), melphalan, cyclophosphamide, carmu... | 481481 | Melphalan and Prednisone (MP) | BCM | Multiple myeloma | Non-curative first-line therapy | OS | Primary | no difference | Melphalan and Prednisone (MP) no difference to BCM for Multiple myeloma (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Vinblastine monotherapy superior to Cyclophosphamide monotherapy for Classical Hodgkin lymphoma (Induction therapy) [endpoint: ORR] | false |
1979-11-15 | Combination chemoimmunotherapy of metastatic breast cancer with 5-fluorouracil, adriamycin, cyclophosphamide, and BCG. One hundred five patients with metastatic breast cancer were treated with 5-fluorouracil, Adriamycin, cyclophosphamide and BCG (FAC-BCG). The results were compared to those observed in a group of 44 pa... | 387212 | FAC | FAC-BCG | Breast cancer | Non-curative first-line therapy | OS in responders | Undesignated | inferior | FAC inferior to FAC-BCG for Breast cancer (Non-curative first-line therapy) [endpoint: OS in responders] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,979 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | CMFT and BCG no difference to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | false |
1980-05-15 | Treatment of women with disseminated or recurrent advanced ovarian cancer with melphalan alone in combination with 5-fluorouracil and dactinomycin or with the combination of cytoxan, 5-fluorouracil and dactinomycin. The purpose of this study was to determine the efficacy of single and multiple drug chemotherapeutic reg... | 7378989 | 5-FU, Cyclophosphamide, Dactinomycin | Melphalan monotherapy | Ovarian cancer | Non-curative first-line therapy | OS | Undesignated | no difference | 5-FU, Cyclophosphamide, Dactinomycin no difference to Melphalan monotherapy for Ovarian cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Hydroxyurea and RT superior to Radiation therapy for Cervical cancer (Definitive therapy) [endpoint: OS] | false |
1980-05-15 | Treatment of women with disseminated or recurrent advanced ovarian cancer with melphalan alone in combination with 5-fluorouracil and dactinomycin or with the combination of cytoxan, 5-fluorouracil and dactinomycin. The purpose of this study was to determine the efficacy of single and multiple drug chemotherapeutic reg... | 7378989 | Melphalan monotherapy | Cyclophosphamide, Dactinomycin, Fluorouracil | Ovarian cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Melphalan monotherapy no difference to Cyclophosphamide, Dactinomycin, Fluorouracil for Ovarian cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Hydroxyurea and RT superior to Radiation therapy for Cervical cancer (Definitive therapy) [endpoint: OS] | false |
1980-05-15 | Treatment of women with disseminated or recurrent advanced ovarian cancer with melphalan alone in combination with 5-fluorouracil and dactinomycin or with the combination of cytoxan, 5-fluorouracil and dactinomycin. The purpose of this study was to determine the efficacy of single and multiple drug chemotherapeutic reg... | 7378989 | Fluorouracil and Melphalan | Melphalan monotherapy | Ovarian cancer | Non-curative first-line therapy | OS | Undesignated | no difference | Fluorouracil and Melphalan no difference to Melphalan monotherapy for Ovarian cancer (Non-curative first-line therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Hydroxyurea and RT superior to Radiation therapy for Cervical cancer (Definitive therapy) [endpoint: OS] | false |
1980-05-15 | Adjuvant chemotherapy, antiestrogen therapy and immunotherapy for stage II breast cancer: 45-month follow-up of a prospective, randomized clinical trial. The results of adjuvant chemotherapy (CMF), endocrine therapy (t), and immunotherapy (BCG) in 318 women who had undergone mastectomy for Stage II breast cancer are re... | 7004624;7368100 | CMFT | CMF | Breast cancer (Node Positive) | Adjuvant therapy | RFS | Undesignated | superior | CMFT superior to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: RFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Semustine monotherapy inferior to Doxorubicin monotherapy for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | false |
1980-05-15 | Adjuvant chemotherapy, antiestrogen therapy and immunotherapy for stage II breast cancer: 45-month follow-up of a prospective, randomized clinical trial. The results of adjuvant chemotherapy (CMF), endocrine therapy (t), and immunotherapy (BCG) in 318 women who had undergone mastectomy for Stage II breast cancer are re... | 7004624;7368100 | CMFT and BCG | CMF | Breast cancer (Node Positive) | Adjuvant therapy | OS | Undesignated | no difference | CMFT and BCG no difference to CMF for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Semustine monotherapy inferior to Doxorubicin monotherapy for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | false |
1980-05-15 | Adjuvant chemotherapy, antiestrogen therapy and immunotherapy for stage II breast cancer: 45-month follow-up of a prospective, randomized clinical trial. The results of adjuvant chemotherapy (CMF), endocrine therapy (t), and immunotherapy (BCG) in 318 women who had undergone mastectomy for Stage II breast cancer are re... | 7004624;7368100 | CMFT and BCG | CMFT | Breast cancer (Node Positive) | Adjuvant therapy | OS | Undesignated | no difference | CMFT and BCG no difference to CMFT for Breast cancer (Node Positive) (Adjuvant therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Semustine monotherapy inferior to Doxorubicin monotherapy for Breast cancer (Non-curative first-line therapy) [endpoint: OS] | false |
1980-06-15 | Treatment of advanced prostatic cancer with parenteral cyproterone acetate: a phase III randomised trial. Forty-two patients with previously untreated T3/4 N1-4 MO/1 prostatic adenocarcinoma were treated with either cyproterone acetate (n = 21; 300 mg intramuscularly per week) or oestradiol undecylate (n = 21; 100 mg i... | 7000222 | Estradiol undecylate monotherapy | Cyproterone acetate monotherapy | Prostate cancer | Non-curative therapy | ORR | Undesignated | inferior | Estradiol undecylate monotherapy inferior to Cyproterone acetate monotherapy for Prostate cancer (Non-curative therapy) [endpoint: ORR] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Dactinomycin and Vincristine superior to Vincristine monotherapy for Wilms tumor (Adjuvant therapy) [endpoint: RFS] | false |
1980-07-18 | Adjuvant chemotherapy for stage II and III breast carcinoma. Stage II or III breast carcinoma patients were assigned to one of three adjuvant chemotherapy groups after mastectomy. The efficacy of melphalan, vs cyclophosphamide, fluorouracil, and prednisone (CFP), vs CFP plus BCG vaccine was compared in 173 patients tre... | 6991733 | CFP and BCG | CFP | Breast cancer | Adjuvant therapy | DFS | Primary | no difference | CFP and BCG no difference to CFP for Breast cancer (Adjuvant therapy) [endpoint: DFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy superior to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: PFS] | false |
1980-07-18 | Adjuvant chemotherapy for stage II and III breast carcinoma. Stage II or III breast carcinoma patients were assigned to one of three adjuvant chemotherapy groups after mastectomy. The efficacy of melphalan, vs cyclophosphamide, fluorouracil, and prednisone (CFP), vs CFP plus BCG vaccine was compared in 173 patients tre... | 6991733 | CFP and BCG | Melphalan monotherapy | Breast cancer | Adjuvant therapy | DFS | Primary | superior | CFP and BCG superior to Melphalan monotherapy for Breast cancer (Adjuvant therapy) [endpoint: DFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1980-07-18 | Adjuvant chemotherapy for stage II and III breast carcinoma. Stage II or III breast carcinoma patients were assigned to one of three adjuvant chemotherapy groups after mastectomy. The efficacy of melphalan, vs cyclophosphamide, fluorouracil, and prednisone (CFP), vs CFP plus BCG vaccine was compared in 173 patients tre... | 6991733 | Melphalan monotherapy | CFP | Breast cancer | Adjuvant therapy | DFS | Primary | inferior | Melphalan monotherapy inferior to CFP for Breast cancer (Adjuvant therapy) [endpoint: DFS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1980-07-26 | Adjuvant treatment with polyadenylic-polyuridylic acid (Polya.Polyu) in operable breast cancer. Adjuvant immunotherapy with polyadenylic-polyuridylic acid (PolyA.PolyU) was tested in a randomised trial on 300 patients with operable breast cancer, all of whom were treated by surgery with or without radiotherapy. They we... | 6105336 | Polya.Polyu | Observation | Breast cancer | Adjuvant therapy | OS | Undesignated | superior | Polya.Polyu superior to Observation for Breast cancer (Adjuvant therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | inferior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Tamoxifen monotherapy no difference to Bilateral oophorectomy monotherapy for Breast cancer (Metastatic) (Non-curative therapy) [endpoint: Could not be determined] | false |
1980-08-15 | A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease. Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whe... | 7397630 | MOPP | COPP (CCNU) | Classical Hodgkin lymphoma | Induction therapy | OS | Undesignated | no difference | MOPP no difference to COPP (CCNU) for Classical Hodgkin lymphoma (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1980-08-15 | A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease. Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whe... | 7397630 | CVPP | COPP (CCNU) | Classical Hodgkin lymphoma | Induction therapy | OS | Undesignated | no difference | CVPP no difference to COPP (CCNU) for Classical Hodgkin lymphoma (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1980-08-15 | A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease. Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whe... | 7397630 | MVPP | CVPP | Classical Hodgkin lymphoma | Induction therapy | OS | Undesignated | no difference | MVPP no difference to CVPP for Classical Hodgkin lymphoma (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1980-08-15 | A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease. Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whe... | 7397630 | MVPP | MOPP | Classical Hodgkin lymphoma | Induction therapy | OS | Undesignated | no difference | MVPP no difference to MOPP for Classical Hodgkin lymphoma (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1980-08-15 | A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease. Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whe... | 7397630 | MOPP | CVPP | Classical Hodgkin lymphoma | Induction therapy | CR rate | Undesignated | inferior | MOPP inferior to CVPP for Classical Hodgkin lymphoma (Induction therapy) [endpoint: CR rate] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | superior | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
1980-08-15 | A new effective four-drug combination of CCNU (1-[2-chloroethyl]-3-cyclohexyl-1-nitrosourea) (NSC-79038), vinblastine, prednisone, and procarbazine for the treatment of advanced Hodgkin's disease. Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whe... | 7397630 | COPP (CCNU) | MVPP | Classical Hodgkin lymphoma | Induction therapy | OS | Undesignated | no difference | COPP (CCNU) no difference to MVPP for Classical Hodgkin lymphoma (Induction therapy) [endpoint: OS] | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a clinical question, compare two treatment options with respect to a specific outcome endpoint and determine their relative efficacy based on current clinical evidence.
Answer with exactly one of ... | no difference | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... |
You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition and clinical context, your task is to provide a concise overview over the relevant components of a treatment that is consistent with current clinical guidelines.
Be as spe... | superior | inferior | no difference | 1,980 | You are a knowledgeable medical assistant supporting oncologists and hematologists in evaluating treatment options.
Given a condition, context, and endpoint, compare two treatment options with respect to the specific outcome endpoint and summarize their relative efficacy based on current clinical evidence.
Task:
Cond... | Placebo superior to Urethane monotherapy for Multiple myeloma (Non-curative therapy) [endpoint: OS] | false |
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