data/38895265_01/test_case.json

{
  "benchmark_id": "38895265_01",
  "sample_system": "",
  "tissue": "Breast",
  "source_type": "cell_line",
  "perturbation_type": "drug",
  "perturbation_name": "Paclitaxel",
  "default_cell_subset": "",
  "description": "HCC1143 TNBC cells treated with paclitaxel.",
  "smiles": "CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C",
  "test_cases": [
    {
      "test_id": "38895265_01_01",
      "target_genes": [
        "ATF3",
        "DDIT3",
        "IRF7",
        "IRF9",
        "JUN",
        "JUNB",
        "MAFF",
        "PLSCR1",
        "SP100"
      ],
      "perturb_var": "time",
      "control": "C",
      "dose_groups": [
        "1.0 nM"
      ],
      "time_groups": [
        "1 day",
        "3 day"
      ],
      "relation": "UP",
      "cell_type": "HCC1143 triple negative breast cancer cell line"
    },
    {
      "test_id": "38895265_01_02",
      "target_genes": [
        "HLA-B",
        "HLA-C",
        "B2M",
        "CD47",
        "CD55",
        "CD59",
        "CD63"
      ],
      "perturb_var": "time",
      "control": "C",
      "dose_groups": [
        "1.0 nM"
      ],
      "time_groups": [
        "1 day",
        "3 day"
      ],
      "relation": "UP",
      "cell_type": "HCC1143 triple negative breast cancer cell line"
    },
    {
      "test_id": "38895265_01_03",
      "target_genes": [
        "CXCL1",
        "CXCL8"
      ],
      "perturb_var": "time",
      "control": "C",
      "dose_groups": [
        "1.0 nM"
      ],
      "time_groups": [
        "1 day",
        "3 day"
      ],
      "relation": "UP",
      "cell_type": "HCC1143 triple negative breast cancer cell line"
    }
  ]
}