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Datasets:
mindflow-cn
/
scDrugPerturb-Bench

Tasks:
Feature Extraction
Languages:
English
Chinese
Size:
10K<n<100K
Tags:
single-cell
transcriptomics
perturbation
drug-response
License:
Dataset card Files
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mindflow-cn commited on
Commit
7c01054
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1 Parent(s): 274910b

Add 37086265_01 test_case.json

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  1. data/37086265_01/test_case.json +132 -0
data/37086265_01/test_case.json ADDED
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+ {
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+ "benchmark_id": "37086265_01",
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+ "sample_system": "",
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+ "tissue": "Lung",
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+ "source_type": "cell_line",
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+ "perturbation_type": "drug",
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+ "perturbation_name": "etoposide",
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+ "default_cell_subset": "",
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+ "description": "WI-38 fetal lung fibroblasts treated with etoposide \u2014 late senescence program (Day 4-10).",
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+ "smiles": "CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O",
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+ "test_cases": [
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+ {
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+ "test_id": "37086265_01_01",
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+ "target_genes": [
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+ "CDKN1A",
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+ "CDKN2A",
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+ "BCL2L2",
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+ "IL6",
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+ "PINK1",
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+ "CCND1",
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+ "DPP4"
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+ ],
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+ "perturb_var": "time",
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+ "control": "C",
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+ "dose_groups": [
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+ "50 uM"
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+ ],
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+ "time_groups": [
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+ "4 day",
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+ "7 day",
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+ "10 day"
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+ ],
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+ "relation": "UP",
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+ "cell_type": "WI-38 fetal lung fibroblast cell line"
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+ },
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+ {
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+ "test_id": "37086265_01_02",
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+ "target_genes": [
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+ "LMNB1",
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+ "LBR"
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+ ],
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+ "perturb_var": "time",
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+ "control": "C",
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+ "dose_groups": [
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+ "50 uM"
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+ ],
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+ "time_groups": [
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+ "4 day",
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+ "7 day",
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+ "10 day"
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+ ],
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+ "relation": "DOWN",
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+ "cell_type": "WI-38 fetal lung fibroblast cell line"
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+ },
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+ {
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+ "test_id": "37086265_01_03",
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+ "target_genes": [],
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+ "perturb_var": "time",
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+ "control": "C",
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+ "dose_groups": [
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+ "50 uM"
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+ ],
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+ "time_groups": [
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+ "4 day",
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+ "7 day",
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+ "10 day"
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+ ],
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+ "relation": "UP",
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+ "cell_type": "WI-38 fetal lung fibroblast cell line"
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+ },
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+ {
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+ "test_id": "37086265_01_04",
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+ "target_genes": [
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+ "GADD45A",
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+ "GDF15",
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+ "MDM2"
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+ ],
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+ "perturb_var": "time",
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+ "control": "C",
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+ "dose_groups": [
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+ "50 uM"
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+ ],
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+ "time_groups": [
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+ "4 day",
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+ "7 day",
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+ "10 day"
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+ ],
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+ "relation": "UP",
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+ "cell_type": "WI-38 fetal lung fibroblast cell line"
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+ },
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+ {
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+ "test_id": "37086265_01_05",
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+ "target_genes": [
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+ "TCF12",
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+ "MAGI2",
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+ "JMJD1C"
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+ ],
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+ "perturb_var": "time",
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+ "control": "C",
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+ "dose_groups": [
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+ "50 uM"
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+ ],
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+ "time_groups": [
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+ "4 day",
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+ "7 day",
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+ "10 day"
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+ ],
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+ "relation": "DOWN",
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+ "cell_type": "WI-38 fetal lung fibroblast cell line"
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+ },
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+ {
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+ "test_id": "37086265_01_06",
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+ "target_genes": [
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+ "SRP14",
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+ "SERF2",
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+ "TSPO"
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+ ],
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+ "perturb_var": "time",
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+ "control": "C",
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+ "dose_groups": [
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+ "50 uM"
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+ ],
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+ "time_groups": [
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+ "4 day",
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+ "7 day",
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+ "10 day"
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+ ],
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+ "relation": "UP",
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+ "cell_type": "WI-38 fetal lung fibroblast cell line"
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+ }
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+ ]
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+ }